Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BmNP11_FL5_M11
(840 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
AJ306454-1|CAC34819.1| 497|Homo sapiens neuronal nicotinic acet... 68 5e-11
Y08416-1|CAA69693.1| 498|Homo sapiens nicotinic acetylcholine r... 66 2e-10
U62439-1|AAB40117.1| 498|Homo sapiens nicotinic acetylcholine r... 66 2e-10
U48861-1|AAA92123.1| 498|Homo sapiens beta 4 nicotinic acetylch... 66 2e-10
BC096082-1|AAH96082.1| 498|Homo sapiens cholinergic receptor, n... 66 2e-10
BC096080-1|AAH96080.1| 498|Homo sapiens cholinergic receptor, n... 66 2e-10
AF306329-1|AAL02062.1| 498|Homo sapiens neuronal nicotinic acet... 66 2e-10
Y08417-1|CAA69694.1| 458|Homo sapiens nicotinic acetylcholine r... 64 6e-10
X67513-1|CAA47851.1| 423|Homo sapiens nicotinic acetylcholine ... 64 6e-10
U62438-1|AAB40116.1| 458|Homo sapiens nicotinic acetylcholine r... 64 6e-10
BC069788-1|AAH69788.1| 458|Homo sapiens cholinergic receptor, n... 64 6e-10
BC069703-1|AAH69703.1| 458|Homo sapiens cholinergic receptor, n... 64 6e-10
BC069681-1|AAH69681.1| 458|Homo sapiens cholinergic receptor, n... 64 6e-10
AF140765-1|AAD33063.1| 458|Homo sapiens neuronal acetylcholine ... 64 6e-10
Y08419-1|CAA69696.1| 468|Homo sapiens nicotinic acetylcholine r... 62 2e-09
U62434-1|AAB40112.1| 468|Homo sapiens nicotinic acetylcholine r... 62 2e-09
BC033639-1|AAH33639.1| 468|Homo sapiens cholinergic receptor, n... 62 2e-09
AJ306481-1|CAC34820.1| 468|Homo sapiens neuronal nicotinic acet... 62 2e-09
Y08418-1|CAA69695.1| 503|Homo sapiens nicotinic acetylcholine r... 62 2e-09
X53559-1|CAA37625.1| 474|Homo sapiens neuronal nicotinic acetyl... 62 2e-09
U62432-1|AAB40110.1| 504|Homo sapiens nicotinic acetylcholine r... 62 2e-09
M37981-1|AAA59942.1| 503|Homo sapiens neuronal nicotinic acetyl... 62 2e-09
BT006897-1|AAP35543.1| 505|Homo sapiens cholinergic receptor, n... 62 2e-09
BT006646-1|AAP35292.1| 489|Homo sapiens cholinergic receptor, n... 62 2e-09
BC098443-1|AAH98443.1| 504|Homo sapiens cholinergic receptor, n... 62 2e-09
BC006114-1|AAH06114.1| 489|Homo sapiens CHRNA3 protein protein. 62 2e-09
BC002996-1|AAH02996.1| 505|Homo sapiens cholinergic receptor, n... 62 2e-09
BC001642-1|AAH01642.1| 505|Homo sapiens cholinergic receptor, n... 62 2e-09
BC000513-1|AAH00513.1| 505|Homo sapiens cholinergic receptor, n... 62 2e-09
AJ007783-1|CAA07682.1| 504|Homo sapiens nicotinic acetylcholine... 62 2e-09
AF385584-1|AAK68110.1| 489|Homo sapiens nicotinic cholinergic r... 62 2e-09
X68275-1|CAA48336.1| 451|Homo sapiens nicotinic receptor beta 4... 62 3e-09
M83712-1|AAA58357.1| 468|Homo sapiens nicotinic receptor alpha ... 61 4e-09
Y16281-1|CAA76154.1| 529|Homo sapiens nicotinic acetylcholine r... 60 1e-08
U62431-1|AAB40109.1| 529|Homo sapiens nicotinic acetylcholine r... 60 1e-08
Y16282-1|CAA76155.1| 494|Homo sapiens nicotinic acetylcholine r... 60 1e-08
U62435-1|AAB40113.1| 494|Homo sapiens nicotinic acetylcholine r... 60 1e-08
M86383-1|AAC84176.1| 502|Homo sapiens nicotinic acetylcholine r... 60 1e-08
BC014456-1|AAH14456.1| 494|Homo sapiens cholinergic receptor, n... 60 1e-08
AB079251-1|BAC06855.1| 494|Homo sapiens Nicotinic acetylcholine... 60 1e-08
X14830-1|CAA32939.1| 501|Homo sapiens protein ( Human mRNA for ... 59 2e-08
BC011371-1|AAH11371.1| 501|Homo sapiens cholinergic receptor, n... 59 2e-08
Y08421-1|CAA69698.1| 627|Homo sapiens nicotinic acetylcholine r... 58 3e-08
X89741-1|CAA61893.1| 627|Homo sapiens neuronal acetylcholine re... 58 3e-08
X87629-1|CAA60959.1| 602|Homo sapiens nicotinic acetylcholine r... 58 3e-08
U62433-1|AAB40111.1| 627|Homo sapiens nicotinic acetylcholine r... 58 3e-08
L35901-1|AAA64743.1| 627|Homo sapiens nicotinic acetylcholine r... 58 3e-08
DQ093071-1|AAY88737.1| 627|Homo sapiens cholinergic receptor, n... 58 3e-08
BC096290-1|AAH96290.1| 627|Homo sapiens cholinergic receptor, n... 58 3e-08
BC023553-1|AAH23553.1| 501|Homo sapiens cholinergic receptor, n... 58 4e-08
Y08415-1|CAA69692.1| 502|Homo sapiens nicotinic acetylcholine r... 56 2e-07
X53179-1|CAA37320.1| 502|Homo sapiens precursor peptide (AA -25... 56 2e-07
U62437-1|AAB40115.1| 502|Homo sapiens nicotinic acetylcholine r... 56 2e-07
BC075041-1|AAH75041.1| 502|Homo sapiens cholinergic receptor, n... 56 2e-07
BC075040-1|AAH75040.1| 502|Homo sapiens cholinergic receptor, n... 56 2e-07
AL592078-3|CAI16184.1| 502|Homo sapiens cholinergic receptor, n... 56 2e-07
AJ001935-1|CAA05108.1| 504|Homo sapiens CHRNB2 protein. 56 2e-07
AF077186-1|AAD45422.1| 502|Homo sapiens neuronal nicotinic acet... 56 2e-07
X66403-1|CAA47030.1| 493|Homo sapiens acetylcholine receptor ep... 55 3e-07
DQ644022-1|ABG35128.1| 456|Homo sapiens 5-HT3 receptor subunit ... 55 3e-07
BC131799-1|AAI31800.1| 447|Homo sapiens 5-hydroxytryptamine (se... 55 3e-07
BC101185-1|AAI01186.1| 374|Homo sapiens HTR3E protein protein. 55 3e-07
BC101183-1|AAI01184.1| 471|Homo sapiens 5-hydroxytryptamine (se... 55 3e-07
BC101182-1|AAI01183.1| 471|Homo sapiens 5-hydroxytryptamine (se... 55 3e-07
AY159813-1|AAO38167.2| 471|Homo sapiens 5-hydroxytryptamine ser... 55 3e-07
AF105999-1|AAD24503.1| 493|Homo sapiens acetylcholine receptor ... 55 3e-07
X01715-1|CAA25861.1| 520|Homo sapiens acetylcholine receptor ga... 55 4e-07
BC113575-1|AAI13576.1| 479|Homo sapiens cholinergic receptor, n... 55 4e-07
BC113549-1|AAI13550.1| 479|Homo sapiens cholinergic receptor, n... 55 4e-07
AY123244-1|AAM74523.1| 479|Homo sapiens nicotinic acetylcholine... 55 4e-07
AJ243342-1|CAB65091.1| 479|Homo sapiens nicotinic acetylcholine... 55 4e-07
AF459285-1|AAL66182.1| 447|Homo sapiens 5-hydroxytryptamine rec... 55 4e-07
AF227732-1|AAF61920.1| 470|Homo sapiens nicotinic acetylcholine... 55 4e-07
AC118275-1|AAY40986.1| 479|Homo sapiens unknown protein. 55 4e-07
AC092165-3|AAY24103.1| 520|Homo sapiens unknown protein. 55 4e-07
Y00762-1|CAA68731.1| 457|Homo sapiens protein ( Human mRNA for ... 54 5e-07
X02502-1|CAA26344.1| 457|Homo sapiens acetylcholine receptor pr... 54 5e-07
S77094-1|AAD14247.1| 457|Homo sapiens nicotinic acetylcholine r... 54 5e-07
BC006314-1|AAH06314.1| 269|Homo sapiens CHRNA1 protein protein. 54 5e-07
AC018890-1|AAY14687.1| 457|Homo sapiens unknown protein. 54 5e-07
AJ295237-1|CAC16144.1| 450|Homo sapiens neuronal nicotinic acet... 54 6e-07
AJ278118-1|CAC20435.1| 450|Homo sapiens neuronal nicotinic acet... 54 6e-07
AF327367-1|AAK14333.1| 450|Homo sapiens nicotinic acetylcholine... 54 6e-07
AF199235-1|AAG00795.2| 450|Homo sapiens nicotinic acetylcholine... 54 6e-07
AY349353-1|AAQ93477.1| 456|Homo sapiens 5-HT3c1 serotonin recep... 53 1e-06
AY349352-1|AAQ93476.1| 441|Homo sapiens 5-HT3c1 serotonin recep... 53 1e-06
X55019-1|CAA38759.1| 517|Homo sapiens acetylcholine receptor de... 51 5e-06
BC093925-1|AAH93925.1| 517|Homo sapiens cholinergic receptor, n... 51 5e-06
BC093923-1|AAH93923.1| 517|Homo sapiens cholinergic receptor, n... 51 5e-06
AC092165-2|AAY24102.1| 517|Homo sapiens unknown protein. 51 5e-06
BC111802-1|AAI11803.1| 465|Homo sapiens CHRNG protein protein. 50 1e-05
Z23141-1|CAA80672.1| 479|Homo sapiens cholinergic receptor, nic... 48 6e-05
Y08420-1|CAA69697.1| 502|Homo sapiens nicotinic acetylcholine r... 48 6e-05
X70297-1|CAA49778.1| 502|Homo sapiens neuronal nicotinic acetyl... 48 6e-05
U62436-1|AAB40114.1| 502|Homo sapiens nicotinic acetylcholine r... 48 6e-05
L08485-1|AAA58490.1| 462|Homo sapiens GABA-benzodiazepine recep... 48 6e-05
BT009830-1|AAP88832.1| 462|Homo sapiens gamma-aminobutyric acid... 48 6e-05
BC113422-1|AAI13423.1| 462|Homo sapiens gamma-aminobutyric acid... 48 6e-05
BC111979-1|AAI11980.1| 462|Homo sapiens gamma-aminobutyric acid... 48 6e-05
BC110597-1|AAI10598.1| 411|Homo sapiens ligand-gated ion channe... 48 6e-05
AK122638-1|BAC85499.1| 266|Homo sapiens yte protein of 76kDa) (... 48 6e-05
AJ586911-1|CAE52911.1| 502|Homo sapiens nicotinic acetylcholine... 48 6e-05
AF512521-1|AAO20969.1| 411|Homo sapiens ligand-gated ion channe... 48 6e-05
AB223030-1|BAE19924.1| 411|Homo sapiens ligand-gated ion-channe... 47 7e-05
AJ003080-1|CAA05853.1| 238|Homo sapiens serotonin receptor prot... 47 1e-04
U40583-1|AAA83561.1| 502|Homo sapiens alpha 7 neuronal nicotini... 46 1e-04
BC096083-1|AAH96083.1| 198|Homo sapiens CHRNB4 protein protein. 46 1e-04
BC096081-1|AAH96081.1| 198|Homo sapiens CHRNB4 protein protein. 46 1e-04
BC028629-1|AAH28629.1| 492|Homo sapiens gamma-aminobutyric acid... 46 1e-04
AF385585-1|AAK68111.1| 502|Homo sapiens nicotinic cholinergic r... 46 1e-04
S62908-1|AAB27279.1| 492|Homo sapiens gamma-aminobutyric acidA ... 46 2e-04
M59216-1|AAA35862.1| 474|Homo sapiens gamma-aminobutyric acid r... 46 2e-04
AF166361-1|AAG12455.1| 492|Homo sapiens GABA receptor subunit a... 46 2e-04
U77731-2|AAB38273.1| 360|Homo sapiens glycine receptor alpha 2B... 46 2e-04
S77554-1|AAB33983.1| 474|Homo sapiens GABAA receptor beta 2 sub... 46 2e-04
S77553-1|AAB33982.1| 512|Homo sapiens GABAA receptor beta 2 sub... 46 2e-04
S67368-1|AAB29370.1| 474|Homo sapiens gamma-aminobutyric acid A... 46 2e-04
CR450343-1|CAG29339.1| 452|Homo sapiens GLRA2 protein. 46 2e-04
BC105639-1|AAI05640.1| 474|Homo sapiens GABRB2 protein protein. 46 2e-04
BC099719-1|AAH99719.1| 474|Homo sapiens GABRB2 protein protein. 46 2e-04
BC099705-1|AAH99705.1| 474|Homo sapiens GABRB2 protein protein. 46 2e-04
AY437084-1|AAR87843.1| 452|Homo sapiens glycine receptor alpha2... 46 2e-04
X52008-1|CAA36257.1| 452|Homo sapiens inhibitory glycine recept... 45 3e-04
X14767-1|CAA32875.1| 474|Homo sapiens GABA-A receptor beta 1 su... 45 3e-04
U77731-1|AAB38272.1| 360|Homo sapiens glycine receptor alpha 2 ... 45 3e-04
BC032864-1|AAH32864.1| 452|Homo sapiens glycine receptor, alpha... 45 3e-04
AY437083-1|AAR87842.1| 452|Homo sapiens glycine receptor alpha2... 45 3e-04
AF053495-1|AAC35290.1| 452|Homo sapiens glycine receptor alpha ... 45 3e-04
S81944-1|AAB36480.1| 453|Homo sapiens gamma-aminobutyric acid t... 44 7e-04
BC099641-1|AAH99641.1| 453|Homo sapiens gamma-aminobutyric acid... 44 7e-04
BC099640-1|AAH99640.1| 453|Homo sapiens gamma-aminobutyric acid... 44 7e-04
BC096242-1|AAH96242.1| 453|Homo sapiens gamma-aminobutyric acid... 44 7e-04
BC096241-1|AAH96241.1| 453|Homo sapiens gamma-aminobutyric acid... 44 7e-04
BC109211-1|AAI09212.1| 632|Homo sapiens gamma-aminobutyric acid... 44 0.001
BC109210-1|AAI09211.1| 632|Homo sapiens gamma-aminobutyric acid... 44 0.001
AF189259-1|AAF70380.1| 632|Homo sapiens GABA-A receptor theta s... 44 0.001
AF144648-1|AAD51172.1| 627|Homo sapiens GABA-A receptor theta p... 44 0.001
U30461-1|AAB52519.1| 554|Homo sapiens GABAA receptor subunit al... 42 0.002
BC035055-1|AAH35055.1| 554|Homo sapiens gamma-aminobutyric acid... 42 0.002
BC033801-1|AAH33801.1| 452|Homo sapiens gamma-aminobutyric acid... 42 0.002
AL391845-4|CAI15436.1| 452|Homo sapiens gamma-aminobutyric acid... 42 0.002
AF016917-1|AAB70007.1| 452|Homo sapiens GABA-A receptor delta s... 42 0.002
BC022449-1|AAH22449.1| 474|Homo sapiens gamma-aminobutyric acid... 41 0.006
X52009-1|CAA36258.1| 449|Homo sapiens inhibitory glycine recept... 40 0.008
BC114947-1|AAI14948.1| 457|Homo sapiens GLRA1 protein protein. 40 0.008
BC074980-1|AAH74980.1| 449|Homo sapiens glycine receptor, alpha... 40 0.008
Z93848-1|CAI41994.1| 376|Homo sapiens glycine receptor, alpha 4... 40 0.011
U95367-1|AAC51357.1| 440|Homo sapiens GABA-A receptor pi subuni... 40 0.011
BC109106-1|AAI09107.1| 440|Homo sapiens gamma-aminobutyric acid... 40 0.011
BC109105-1|AAI09106.1| 440|Homo sapiens gamma-aminobutyric acid... 40 0.011
BC074865-1|AAH74865.1| 440|Homo sapiens gamma-aminobutyric acid... 40 0.011
BC074810-1|AAH74810.1| 440|Homo sapiens gamma-aminobutyric acid... 40 0.011
AL049610-1|CAI42158.1| 376|Homo sapiens glycine receptor, alpha... 40 0.011
AF009702-1|AAC24194.1| 440|Homo sapiens GABA-A receptor pi subu... 40 0.011
U93917-1|AAC39917.1| 449|Homo sapiens glycine receptor alpha 3 ... 39 0.020
BC036086-1|AAH36086.1| 464|Homo sapiens glycine receptor, alpha... 39 0.020
AF017724-1|AAC39919.1| 465|Homo sapiens glycine receptor alpha ... 39 0.020
BC114967-1|AAI14968.1| 366|Homo sapiens GLRA1 protein protein. 38 0.045
AB209359-1|BAD92596.1| 533|Homo sapiens cholinergic receptor, n... 33 0.97
BC096291-1|AAH96291.1| 556|Homo sapiens CHRNA4 protein protein. 33 1.7
BC146774-1|AAI46775.1| 1114|Homo sapiens GPR124 protein protein. 31 6.9
AY181242-1|AAO27354.1| 1331|Homo sapiens G protein-coupled recep... 31 6.9
AK074099-1|BAB84925.1| 1310|Homo sapiens FLJ00170 protein protein. 31 6.9
AF378755-1|AAL11992.1| 1331|Homo sapiens tumor endothelial marke... 31 6.9
AB040964-1|BAA96055.2| 1206|Homo sapiens KIAA1531 protein protein. 31 6.9
>AJ306454-1|CAC34819.1| 497|Homo sapiens neuronal nicotinic
acetylcholine receptor beta-4 subunit protein.
Length = 497
Score = 67.7 bits (158), Expect = 5e-11
Identities = 45/171 (26%), Positives = 78/171 (45%), Gaps = 8/171 (4%)
Frame = +2
Query: 92 AIASAAECENATSLSLMIDSLL--ATYDRESPP--DSKIVVNLTLHLRHA---NIRESES 250
A+ C A + ++D LL Y+ P S ++++ L L A ++ E E
Sbjct: 14 ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQ 73
Query: 251 TVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRAR 427
+ L+ W D RL+WN+ + G + + ++R+W PD+VL N T
Sbjct: 74 IMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNDGTYEVSVYTNLI 133
Query: 428 VSNNGSVSWIKRLDISTPISMQLDNWXNDMQTCTFKFGSRMHNSDXMDXVI 580
V +NGSV W+ + +++ + D Q CT KF S ++ +D V+
Sbjct: 134 VRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRSWTYDHTEIDMVL 184
>Y08416-1|CAA69693.1| 498|Homo sapiens nicotinic acetylcholine
receptor beta4 subunit precursor protein.
Length = 498
Score = 65.7 bits (153), Expect = 2e-10
Identities = 46/172 (26%), Positives = 79/172 (45%), Gaps = 9/172 (5%)
Frame = +2
Query: 92 AIASAAECENATSLSLMIDSLL--ATYDRESPP--DSKIVVNLTLHLRHA---NIRESES 250
A+ C A + ++D LL Y+ P S ++++ L L A ++ E E
Sbjct: 14 ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQ 73
Query: 251 TVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRA 424
+ L+ W D RL+WN+ + G + + ++R+W PD+VL N A T
Sbjct: 74 IMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNADGTYEVSVYTNL 133
Query: 425 RVSNNGSVSWIKRLDISTPISMQLDNWXNDMQTCTFKFGSRMHNSDXMDXVI 580
V +NGSV W+ + +++ + D Q CT KF S ++ +D V+
Sbjct: 134 IVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRSWTYDHTEIDMVL 185
>U62439-1|AAB40117.1| 498|Homo sapiens nicotinic acetylcholine
receptor beta4 subunit precursor protein.
Length = 498
Score = 65.7 bits (153), Expect = 2e-10
Identities = 46/172 (26%), Positives = 79/172 (45%), Gaps = 9/172 (5%)
Frame = +2
Query: 92 AIASAAECENATSLSLMIDSLL--ATYDRESPP--DSKIVVNLTLHLRHA---NIRESES 250
A+ C A + ++D LL Y+ P S ++++ L L A ++ E E
Sbjct: 14 ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQ 73
Query: 251 TVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRA 424
+ L+ W D RL+WN+ + G + + ++R+W PD+VL N A T
Sbjct: 74 IMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNADGTYEVSVYTNL 133
Query: 425 RVSNNGSVSWIKRLDISTPISMQLDNWXNDMQTCTFKFGSRMHNSDXMDXVI 580
V +NGSV W+ + +++ + D Q CT KF S ++ +D V+
Sbjct: 134 IVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRSWTYDHTEIDMVL 185
>U48861-1|AAA92123.1| 498|Homo sapiens beta 4 nicotinic
acetylcholine receptor subunit protein.
Length = 498
Score = 65.7 bits (153), Expect = 2e-10
Identities = 46/172 (26%), Positives = 79/172 (45%), Gaps = 9/172 (5%)
Frame = +2
Query: 92 AIASAAECENATSLSLMIDSLL--ATYDRESPP--DSKIVVNLTLHLRHA---NIRESES 250
A+ C A + ++D LL Y+ P S ++++ L L A ++ E E
Sbjct: 14 ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQ 73
Query: 251 TVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRA 424
+ L+ W D RL+WN+ + G + + ++R+W PD+VL N A T
Sbjct: 74 IMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNADGTYEVSVYTNL 133
Query: 425 RVSNNGSVSWIKRLDISTPISMQLDNWXNDMQTCTFKFGSRMHNSDXMDXVI 580
V +NGSV W+ + +++ + D Q CT KF S ++ +D V+
Sbjct: 134 IVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRSWTYDHTEIDMVL 185
>BC096082-1|AAH96082.1| 498|Homo sapiens cholinergic receptor,
nicotinic, beta 4 protein.
Length = 498
Score = 65.7 bits (153), Expect = 2e-10
Identities = 46/172 (26%), Positives = 79/172 (45%), Gaps = 9/172 (5%)
Frame = +2
Query: 92 AIASAAECENATSLSLMIDSLL--ATYDRESPP--DSKIVVNLTLHLRHA---NIRESES 250
A+ C A + ++D LL Y+ P S ++++ L L A ++ E E
Sbjct: 14 ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQ 73
Query: 251 TVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRA 424
+ L+ W D RL+WN+ + G + + ++R+W PD+VL N A T
Sbjct: 74 IMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNADGTYEVSVYTNL 133
Query: 425 RVSNNGSVSWIKRLDISTPISMQLDNWXNDMQTCTFKFGSRMHNSDXMDXVI 580
V +NGSV W+ + +++ + D Q CT KF S ++ +D V+
Sbjct: 134 IVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRSWTYDHTEIDMVL 185
>BC096080-1|AAH96080.1| 498|Homo sapiens cholinergic receptor,
nicotinic, beta 4 protein.
Length = 498
Score = 65.7 bits (153), Expect = 2e-10
Identities = 46/172 (26%), Positives = 79/172 (45%), Gaps = 9/172 (5%)
Frame = +2
Query: 92 AIASAAECENATSLSLMIDSLL--ATYDRESPP--DSKIVVNLTLHLRHA---NIRESES 250
A+ C A + ++D LL Y+ P S ++++ L L A ++ E E
Sbjct: 14 ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQ 73
Query: 251 TVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRA 424
+ L+ W D RL+WN+ + G + + ++R+W PD+VL N A T
Sbjct: 74 IMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNADGTYEVSVYTNL 133
Query: 425 RVSNNGSVSWIKRLDISTPISMQLDNWXNDMQTCTFKFGSRMHNSDXMDXVI 580
V +NGSV W+ + +++ + D Q CT KF S ++ +D V+
Sbjct: 134 IVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRSWTYDHTEIDMVL 185
>AF306329-1|AAL02062.1| 498|Homo sapiens neuronal nicotinic
acetylcholine receptor beta 4 subunit protein.
Length = 498
Score = 65.7 bits (153), Expect = 2e-10
Identities = 46/172 (26%), Positives = 79/172 (45%), Gaps = 9/172 (5%)
Frame = +2
Query: 92 AIASAAECENATSLSLMIDSLL--ATYDRESPP--DSKIVVNLTLHLRHA---NIRESES 250
A+ C A + ++D LL Y+ P S ++++ L L A ++ E E
Sbjct: 14 ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQ 73
Query: 251 TVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRA 424
+ L+ W D RL+WN+ + G + + ++R+W PD+VL N A T
Sbjct: 74 IMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNADGTYEVSVYTNL 133
Query: 425 RVSNNGSVSWIKRLDISTPISMQLDNWXNDMQTCTFKFGSRMHNSDXMDXVI 580
V +NGSV W+ + +++ + D Q CT KF S ++ +D V+
Sbjct: 134 IVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRSWTYDHTEIDMVL 185
>Y08417-1|CAA69694.1| 458|Homo sapiens nicotinic acetylcholine
receptor beta3 subunit precursor protein.
Length = 458
Score = 64.1 bits (149), Expect = 6e-10
Identities = 33/105 (31%), Positives = 52/105 (49%), Gaps = 2/105 (1%)
Frame = +2
Query: 272 LQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLL-NAAATTAGDYALRARVSNNGS 445
L+ W D +L WN ++G + V SE LW PD+VL NA G + V +NG+
Sbjct: 81 LKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFEGSLMTKVIVKSNGT 140
Query: 446 VSWIKRLDISTPISMQLDNWXNDMQTCTFKFGSRMHNSDXMDXVI 580
V W + +M + + D Q C+ KFGS ++ +D ++
Sbjct: 141 VVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGTMVDLIL 185
>X67513-1|CAA47851.1| 423|Homo sapiens nicotinic acetylcholine
receptor beta-3 subunit protein.
Length = 423
Score = 64.1 bits (149), Expect = 6e-10
Identities = 33/105 (31%), Positives = 52/105 (49%), Gaps = 2/105 (1%)
Frame = +2
Query: 272 LQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLL-NAAATTAGDYALRARVSNNGS 445
L+ W D +L WN ++G + V SE LW PD+VL NA G + V +NG+
Sbjct: 46 LKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFEGSLMTKVIVKSNGT 105
Query: 446 VSWIKRLDISTPISMQLDNWXNDMQTCTFKFGSRMHNSDXMDXVI 580
V W + +M + + D Q C+ KFGS ++ +D ++
Sbjct: 106 VVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGTMVDLIL 150
>U62438-1|AAB40116.1| 458|Homo sapiens nicotinic acetylcholine
receptor beta3 subunit precursor protein.
Length = 458
Score = 64.1 bits (149), Expect = 6e-10
Identities = 33/105 (31%), Positives = 52/105 (49%), Gaps = 2/105 (1%)
Frame = +2
Query: 272 LQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLL-NAAATTAGDYALRARVSNNGS 445
L+ W D +L WN ++G + V SE LW PD+VL NA G + V +NG+
Sbjct: 81 LKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFEGSLMTKVIVKSNGT 140
Query: 446 VSWIKRLDISTPISMQLDNWXNDMQTCTFKFGSRMHNSDXMDXVI 580
V W + +M + + D Q C+ KFGS ++ +D ++
Sbjct: 141 VVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGTMVDLIL 185
>BC069788-1|AAH69788.1| 458|Homo sapiens cholinergic receptor,
nicotinic, beta 3 protein.
Length = 458
Score = 64.1 bits (149), Expect = 6e-10
Identities = 33/105 (31%), Positives = 52/105 (49%), Gaps = 2/105 (1%)
Frame = +2
Query: 272 LQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLL-NAAATTAGDYALRARVSNNGS 445
L+ W D +L WN ++G + V SE LW PD+VL NA G + V +NG+
Sbjct: 81 LKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFEGSLMTKVIVKSNGT 140
Query: 446 VSWIKRLDISTPISMQLDNWXNDMQTCTFKFGSRMHNSDXMDXVI 580
V W + +M + + D Q C+ KFGS ++ +D ++
Sbjct: 141 VVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGTMVDLIL 185
>BC069703-1|AAH69703.1| 458|Homo sapiens cholinergic receptor,
nicotinic, beta 3 protein.
Length = 458
Score = 64.1 bits (149), Expect = 6e-10
Identities = 33/105 (31%), Positives = 52/105 (49%), Gaps = 2/105 (1%)
Frame = +2
Query: 272 LQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLL-NAAATTAGDYALRARVSNNGS 445
L+ W D +L WN ++G + V SE LW PD+VL NA G + V +NG+
Sbjct: 81 LKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFEGSLMTKVIVKSNGT 140
Query: 446 VSWIKRLDISTPISMQLDNWXNDMQTCTFKFGSRMHNSDXMDXVI 580
V W + +M + + D Q C+ KFGS ++ +D ++
Sbjct: 141 VVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGTMVDLIL 185
>BC069681-1|AAH69681.1| 458|Homo sapiens cholinergic receptor,
nicotinic, beta 3 protein.
Length = 458
Score = 64.1 bits (149), Expect = 6e-10
Identities = 33/105 (31%), Positives = 52/105 (49%), Gaps = 2/105 (1%)
Frame = +2
Query: 272 LQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLL-NAAATTAGDYALRARVSNNGS 445
L+ W D +L WN ++G + V SE LW PD+VL NA G + V +NG+
Sbjct: 81 LKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFEGSLMTKVIVKSNGT 140
Query: 446 VSWIKRLDISTPISMQLDNWXNDMQTCTFKFGSRMHNSDXMDXVI 580
V W + +M + + D Q C+ KFGS ++ +D ++
Sbjct: 141 VVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGTMVDLIL 185
>AF140765-1|AAD33063.1| 458|Homo sapiens neuronal acetylcholine
receptor beta-3 subunit precursor protein.
Length = 458
Score = 64.1 bits (149), Expect = 6e-10
Identities = 33/105 (31%), Positives = 52/105 (49%), Gaps = 2/105 (1%)
Frame = +2
Query: 272 LQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLL-NAAATTAGDYALRARVSNNGS 445
L+ W D +L WN ++G + V SE LW PD+VL NA G + V +NG+
Sbjct: 81 LKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFEGSLMTKVIVKSNGT 140
Query: 446 VSWIKRLDISTPISMQLDNWXNDMQTCTFKFGSRMHNSDXMDXVI 580
V W + +M + + D Q C+ KFGS ++ +D ++
Sbjct: 141 VVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGTMVDLIL 185
>Y08419-1|CAA69696.1| 468|Homo sapiens nicotinic acetylcholine
receptor alpha5 subunit precursor protein.
Length = 468
Score = 62.5 bits (145), Expect = 2e-09
Identities = 36/154 (23%), Positives = 72/154 (46%), Gaps = 6/154 (3%)
Frame = +2
Query: 140 MIDSLLATYDRESPP----DSKIVVNLTLHLRH-ANIRESESTVRILADLQMNWIDKRLS 304
++ L Y+R P + KI + L + ++ E + L+ WID +L
Sbjct: 50 LLKDLFQDYERWVRPVEHLNDKIKIKFGLAISQLVDVDEKNQLMTTNVWLKQEWIDVKLR 109
Query: 305 WNAGEWG-CSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVSWIKRLDISTP 481
WN ++G V S+ +W PD+VL + A + + + NG+V+W + +
Sbjct: 110 WNPDDYGGIKVIRVPSDSVWTPDIVLFDNADGRFEGTSTKTVIRYNGTVTWTPPANYKSS 169
Query: 482 ISMQLDNWXNDMQTCTFKFGSRMHNSDXMDXVID 583
++ + + D+Q C+ KFGS ++ +D +++
Sbjct: 170 CTIDVTFFPFDLQNCSMKFGSWTYDGSQVDIILE 203
>U62434-1|AAB40112.1| 468|Homo sapiens nicotinic acetylcholine
receptor alpha5 subunit precursor protein.
Length = 468
Score = 62.5 bits (145), Expect = 2e-09
Identities = 36/154 (23%), Positives = 72/154 (46%), Gaps = 6/154 (3%)
Frame = +2
Query: 140 MIDSLLATYDRESPP----DSKIVVNLTLHLRH-ANIRESESTVRILADLQMNWIDKRLS 304
++ L Y+R P + KI + L + ++ E + L+ WID +L
Sbjct: 50 LLKDLFQDYERWVRPVEHLNDKIKIKFGLAISQLVDVDEKNQLMTTNVWLKQEWIDVKLR 109
Query: 305 WNAGEWG-CSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVSWIKRLDISTP 481
WN ++G V S+ +W PD+VL + A + + + NG+V+W + +
Sbjct: 110 WNPDDYGGIKVIRVPSDSVWTPDIVLFDNADGRFEGTSTKTVIRYNGTVTWTPPANYKSS 169
Query: 482 ISMQLDNWXNDMQTCTFKFGSRMHNSDXMDXVID 583
++ + + D+Q C+ KFGS ++ +D +++
Sbjct: 170 CTIDVTFFPFDLQNCSMKFGSWTYDGSQVDIILE 203
>BC033639-1|AAH33639.1| 468|Homo sapiens cholinergic receptor,
nicotinic, alpha 5 protein.
Length = 468
Score = 62.5 bits (145), Expect = 2e-09
Identities = 36/154 (23%), Positives = 72/154 (46%), Gaps = 6/154 (3%)
Frame = +2
Query: 140 MIDSLLATYDRESPP----DSKIVVNLTLHLRH-ANIRESESTVRILADLQMNWIDKRLS 304
++ L Y+R P + KI + L + ++ E + L+ WID +L
Sbjct: 50 LLKDLFQDYERWVRPVEHLNDKIKIKFGLAISQLVDVDEKNQLMTTNVWLKQEWIDVKLR 109
Query: 305 WNAGEWG-CSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVSWIKRLDISTP 481
WN ++G V S+ +W PD+VL + A + + + NG+V+W + +
Sbjct: 110 WNPDDYGGIKVIRVPSDSVWTPDIVLFDNADGRFEGTSTKTVIRYNGTVTWTPPANYKSS 169
Query: 482 ISMQLDNWXNDMQTCTFKFGSRMHNSDXMDXVID 583
++ + + D+Q C+ KFGS ++ +D +++
Sbjct: 170 CTIDVTFFPFDLQNCSMKFGSWTYDGSQVDIILE 203
>AJ306481-1|CAC34820.1| 468|Homo sapiens neuronal nicotinic
acetylcholine receptor alpha-5subunit protein.
Length = 468
Score = 62.5 bits (145), Expect = 2e-09
Identities = 36/154 (23%), Positives = 72/154 (46%), Gaps = 6/154 (3%)
Frame = +2
Query: 140 MIDSLLATYDRESPP----DSKIVVNLTLHLRH-ANIRESESTVRILADLQMNWIDKRLS 304
++ L Y+R P + KI + L + ++ E + L+ WID +L
Sbjct: 50 LLKDLFQDYERWVRPVEHLNDKIKIKFGLAISQLVDVDEKNQLMTTNVWLKQEWIDVKLR 109
Query: 305 WNAGEWG-CSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVSWIKRLDISTP 481
WN ++G V S+ +W PD+VL + A + + + NG+V+W + +
Sbjct: 110 WNPDDYGGIKVIRVPSDSVWTPDIVLFDNADGRFEGTSTKTVIRYNGTVTWTPPANYKSS 169
Query: 482 ISMQLDNWXNDMQTCTFKFGSRMHNSDXMDXVID 583
++ + + D+Q C+ KFGS ++ +D +++
Sbjct: 170 CTIDVTFFPFDLQNCSMKFGSWTYDGSQVDIILE 203
>Y08418-1|CAA69695.1| 503|Homo sapiens nicotinic acetylcholine
receptor alpha3 subunit precursor protein.
Length = 503
Score = 62.1 bits (144), Expect = 2e-09
Identities = 31/105 (29%), Positives = 55/105 (52%), Gaps = 2/105 (1%)
Frame = +2
Query: 272 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 445
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 85 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 144
Query: 446 VSWIKRLDISTPISMQLDNWXNDMQTCTFKFGSRMHNSDXMDXVI 580
V+WI + + + + D Q CT KFGS ++ +D V+
Sbjct: 145 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVL 189
>X53559-1|CAA37625.1| 474|Homo sapiens neuronal nicotinic
acetylcholine receptor alpha-3merase protein.
Length = 474
Score = 62.1 bits (144), Expect = 2e-09
Identities = 31/105 (29%), Positives = 55/105 (52%), Gaps = 2/105 (1%)
Frame = +2
Query: 272 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 445
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 56 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 115
Query: 446 VSWIKRLDISTPISMQLDNWXNDMQTCTFKFGSRMHNSDXMDXVI 580
V+WI + + + + D Q CT KFGS ++ +D V+
Sbjct: 116 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVL 160
>U62432-1|AAB40110.1| 504|Homo sapiens nicotinic acetylcholine
receptor alpha3 subunit precursor protein.
Length = 504
Score = 62.1 bits (144), Expect = 2e-09
Identities = 31/105 (29%), Positives = 55/105 (52%), Gaps = 2/105 (1%)
Frame = +2
Query: 272 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 445
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 86 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 145
Query: 446 VSWIKRLDISTPISMQLDNWXNDMQTCTFKFGSRMHNSDXMDXVI 580
V+WI + + + + D Q CT KFGS ++ +D V+
Sbjct: 146 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVL 190
>M37981-1|AAA59942.1| 503|Homo sapiens neuronal nicotinic
acetylcholine receptor protein.
Length = 503
Score = 62.1 bits (144), Expect = 2e-09
Identities = 31/105 (29%), Positives = 55/105 (52%), Gaps = 2/105 (1%)
Frame = +2
Query: 272 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 445
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 85 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 144
Query: 446 VSWIKRLDISTPISMQLDNWXNDMQTCTFKFGSRMHNSDXMDXVI 580
V+WI + + + + D Q CT KFGS ++ +D V+
Sbjct: 145 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVL 189
>BT006897-1|AAP35543.1| 505|Homo sapiens cholinergic receptor,
nicotinic, alpha polypeptide 3 protein.
Length = 505
Score = 62.1 bits (144), Expect = 2e-09
Identities = 31/105 (29%), Positives = 55/105 (52%), Gaps = 2/105 (1%)
Frame = +2
Query: 272 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 445
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 87 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 146
Query: 446 VSWIKRLDISTPISMQLDNWXNDMQTCTFKFGSRMHNSDXMDXVI 580
V+WI + + + + D Q CT KFGS ++ +D V+
Sbjct: 147 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVL 191
>BT006646-1|AAP35292.1| 489|Homo sapiens cholinergic receptor,
nicotinic, alpha polypeptide 3 protein.
Length = 489
Score = 62.1 bits (144), Expect = 2e-09
Identities = 31/105 (29%), Positives = 55/105 (52%), Gaps = 2/105 (1%)
Frame = +2
Query: 272 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 445
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 87 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 146
Query: 446 VSWIKRLDISTPISMQLDNWXNDMQTCTFKFGSRMHNSDXMDXVI 580
V+WI + + + + D Q CT KFGS ++ +D V+
Sbjct: 147 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVL 191
>BC098443-1|AAH98443.1| 504|Homo sapiens cholinergic receptor,
nicotinic, alpha 3 protein.
Length = 504
Score = 62.1 bits (144), Expect = 2e-09
Identities = 31/105 (29%), Positives = 55/105 (52%), Gaps = 2/105 (1%)
Frame = +2
Query: 272 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 445
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 86 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 145
Query: 446 VSWIKRLDISTPISMQLDNWXNDMQTCTFKFGSRMHNSDXMDXVI 580
V+WI + + + + D Q CT KFGS ++ +D V+
Sbjct: 146 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVL 190
>BC006114-1|AAH06114.1| 489|Homo sapiens CHRNA3 protein protein.
Length = 489
Score = 62.1 bits (144), Expect = 2e-09
Identities = 31/105 (29%), Positives = 55/105 (52%), Gaps = 2/105 (1%)
Frame = +2
Query: 272 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 445
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 87 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 146
Query: 446 VSWIKRLDISTPISMQLDNWXNDMQTCTFKFGSRMHNSDXMDXVI 580
V+WI + + + + D Q CT KFGS ++ +D V+
Sbjct: 147 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVL 191
>BC002996-1|AAH02996.1| 505|Homo sapiens cholinergic receptor,
nicotinic, alpha 3 protein.
Length = 505
Score = 62.1 bits (144), Expect = 2e-09
Identities = 31/105 (29%), Positives = 55/105 (52%), Gaps = 2/105 (1%)
Frame = +2
Query: 272 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 445
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 87 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 146
Query: 446 VSWIKRLDISTPISMQLDNWXNDMQTCTFKFGSRMHNSDXMDXVI 580
V+WI + + + + D Q CT KFGS ++ +D V+
Sbjct: 147 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVL 191
>BC001642-1|AAH01642.1| 505|Homo sapiens cholinergic receptor,
nicotinic, alpha 3 protein.
Length = 505
Score = 62.1 bits (144), Expect = 2e-09
Identities = 31/105 (29%), Positives = 55/105 (52%), Gaps = 2/105 (1%)
Frame = +2
Query: 272 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 445
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 87 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 146
Query: 446 VSWIKRLDISTPISMQLDNWXNDMQTCTFKFGSRMHNSDXMDXVI 580
V+WI + + + + D Q CT KFGS ++ +D V+
Sbjct: 147 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVL 191
>BC000513-1|AAH00513.1| 505|Homo sapiens cholinergic receptor,
nicotinic, alpha 3 protein.
Length = 505
Score = 62.1 bits (144), Expect = 2e-09
Identities = 31/105 (29%), Positives = 55/105 (52%), Gaps = 2/105 (1%)
Frame = +2
Query: 272 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 445
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 87 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 146
Query: 446 VSWIKRLDISTPISMQLDNWXNDMQTCTFKFGSRMHNSDXMDXVI 580
V+WI + + + + D Q CT KFGS ++ +D V+
Sbjct: 147 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVL 191
>AJ007783-1|CAA07682.1| 504|Homo sapiens nicotinic acetylcholine
receptor alpha-3 subunit protein.
Length = 504
Score = 62.1 bits (144), Expect = 2e-09
Identities = 31/105 (29%), Positives = 55/105 (52%), Gaps = 2/105 (1%)
Frame = +2
Query: 272 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 445
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 86 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 145
Query: 446 VSWIKRLDISTPISMQLDNWXNDMQTCTFKFGSRMHNSDXMDXVI 580
V+WI + + + + D Q CT KFGS ++ +D V+
Sbjct: 146 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVL 190
>AF385584-1|AAK68110.1| 489|Homo sapiens nicotinic cholinergic
receptor alpha 3 protein.
Length = 489
Score = 62.1 bits (144), Expect = 2e-09
Identities = 31/105 (29%), Positives = 55/105 (52%), Gaps = 2/105 (1%)
Frame = +2
Query: 272 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 445
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 81 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 140
Query: 446 VSWIKRLDISTPISMQLDNWXNDMQTCTFKFGSRMHNSDXMDXVI 580
V+WI + + + + D Q CT KFGS ++ +D V+
Sbjct: 141 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVL 185
>X68275-1|CAA48336.1| 451|Homo sapiens nicotinic receptor beta 4
subunit protein.
Length = 451
Score = 61.7 bits (143), Expect = 3e-09
Identities = 37/132 (28%), Positives = 63/132 (47%), Gaps = 3/132 (2%)
Frame = +2
Query: 194 IVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 367
I + L L L ++ E + + L+ W D RL+WN+ + G + + ++R+W P
Sbjct: 7 ISIKLQLSLAQLISVNERDEIMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLP 66
Query: 368 DVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWXNDMQTCTFKFGS 544
D+VL N A T V +NGSV W+ + +++ + D Q CT KF S
Sbjct: 67 DIVLYNNADGTYEVSVYTNLIVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRS 126
Query: 545 RMHNSDXMDXVI 580
++ +D V+
Sbjct: 127 WTYDHTEIDMVL 138
>M83712-1|AAA58357.1| 468|Homo sapiens nicotinic receptor alpha 5
subunit protein.
Length = 468
Score = 61.3 bits (142), Expect = 4e-09
Identities = 36/154 (23%), Positives = 71/154 (46%), Gaps = 6/154 (3%)
Frame = +2
Query: 140 MIDSLLATYDRESPP----DSKIVVNLTLHLRH-ANIRESESTVRILADLQMNWIDKRLS 304
++ L Y+R P + KI + L + ++ E + L+ WID +L
Sbjct: 50 LLKDLFQDYERWVRPVEHLNDKIKIKFGLAISQLVDVDEKNQLMTTNVWLKQEWIDVKLR 109
Query: 305 WNAGEWG-CSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVSWIKRLDISTP 481
WN ++G V S+ W PD+VL + A + + + NG+V+W + +
Sbjct: 110 WNPDDYGGIKVIRVPSDSSWTPDIVLFDNADGRFEGTSTKTVIRYNGTVTWTPPANYKSS 169
Query: 482 ISMQLDNWXNDMQTCTFKFGSRMHNSDXMDXVID 583
++ + + D+Q C+ KFGS ++ +D +++
Sbjct: 170 CTIDVTFFPFDLQNCSMKFGSWTYDGSQVDIILE 203
>Y16281-1|CAA76154.1| 529|Homo sapiens nicotinic acetylcholine
receptor alpha2 subunit precursor protein.
Length = 529
Score = 60.1 bits (139), Expect = 1e-08
Identities = 33/102 (32%), Positives = 52/102 (50%), Gaps = 2/102 (1%)
Frame = +2
Query: 272 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAA-ATTAGDYALRARVSNNGS 445
L+ W D +L WN ++G T L V SE +W PD+VL N A A + +A + + G+
Sbjct: 111 LKQEWSDYKLRWNPADFGNITSLRVPSEMIWIPDIVLYNNADGEFAVTHMTKAHLFSTGT 170
Query: 446 VSWIKRLDISTPISMQLDNWXNDMQTCTFKFGSRMHNSDXMD 571
V W+ + S+ + + D Q C KFGS ++ +D
Sbjct: 171 VHWVPPAIYKSSCSIDVTFFPFDQQNCKMKFGSWTYDKAKID 212
>U62431-1|AAB40109.1| 529|Homo sapiens nicotinic acetylcholine
receptor alpha2 subunit precursor protein.
Length = 529
Score = 60.1 bits (139), Expect = 1e-08
Identities = 33/102 (32%), Positives = 52/102 (50%), Gaps = 2/102 (1%)
Frame = +2
Query: 272 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAA-ATTAGDYALRARVSNNGS 445
L+ W D +L WN ++G T L V SE +W PD+VL N A A + +A + + G+
Sbjct: 111 LKQEWSDYKLRWNPADFGNITSLRVPSEMIWIPDIVLYNNADGEFAVTHMTKAHLFSTGT 170
Query: 446 VSWIKRLDISTPISMQLDNWXNDMQTCTFKFGSRMHNSDXMD 571
V W+ + S+ + + D Q C KFGS ++ +D
Sbjct: 171 VHWVPPAIYKSSCSIDVTFFPFDQQNCKMKFGSWTYDKAKID 212
>Y16282-1|CAA76155.1| 494|Homo sapiens nicotinic acetylcholine
receptor alpha6 subunit precursor protein.
Length = 494
Score = 59.7 bits (138), Expect = 1e-08
Identities = 41/166 (24%), Positives = 76/166 (45%), Gaps = 10/166 (6%)
Frame = +2
Query: 113 CENATSLSLMIDSLLATYDRESPPDSKIVVNLTLHL-----RHANIRESESTVRILADLQ 277
C + + L + Y++ P + +T+H + AN+ E + L+
Sbjct: 28 CVGCATEERLFHKLFSHYNQFIRPVENVSDPVTVHFEVAITQLANVDEVNQIMETNLWLR 87
Query: 278 MNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNG 442
W D +L W+ E+ G T V ++++W+PD+VL N A GD+ + +A + NG
Sbjct: 88 HIWNDYKLRWDPMEYDGIETLRVPADKIWKPDIVLYNNAV---GDFQVEGKTKALLKYNG 144
Query: 443 SVSWIKRLDISTPISMQLDNWXNDMQTCTFKFGSRMHNSDXMDXVI 580
++W + M + + D Q C+ KFGS ++ +D +I
Sbjct: 145 MITWTPPAIFKSSCPMDITFFPFDHQNCSLKFGSWTYDKAEIDLLI 190
>U62435-1|AAB40113.1| 494|Homo sapiens nicotinic acetylcholine
receptor alpha6 subunit precursor protein.
Length = 494
Score = 59.7 bits (138), Expect = 1e-08
Identities = 41/166 (24%), Positives = 76/166 (45%), Gaps = 10/166 (6%)
Frame = +2
Query: 113 CENATSLSLMIDSLLATYDRESPPDSKIVVNLTLHL-----RHANIRESESTVRILADLQ 277
C + + L + Y++ P + +T+H + AN+ E + L+
Sbjct: 28 CVGCATEERLFHKLFSHYNQFIRPVENVSDPVTVHFEVAITQLANVDEVNQIMETNLWLR 87
Query: 278 MNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNG 442
W D +L W+ E+ G T V ++++W+PD+VL N A GD+ + +A + NG
Sbjct: 88 HIWNDYKLRWDPMEYDGIETLRVPADKIWKPDIVLYNNAV---GDFQVEGKTKALLKYNG 144
Query: 443 SVSWIKRLDISTPISMQLDNWXNDMQTCTFKFGSRMHNSDXMDXVI 580
++W + M + + D Q C+ KFGS ++ +D +I
Sbjct: 145 MITWTPPAIFKSSCPMDITFFPFDHQNCSLKFGSWTYDKAEIDLLI 190
>M86383-1|AAC84176.1| 502|Homo sapiens nicotinic acetylcholine
receptor alpha 3 subunit precursor protein.
Length = 502
Score = 59.7 bits (138), Expect = 1e-08
Identities = 32/108 (29%), Positives = 57/108 (52%), Gaps = 5/108 (4%)
Frame = +2
Query: 272 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYAL----RARVSN 436
L+ W D +L WN +G + ++ V ++++W+PD+VL N A GD+ + +A +
Sbjct: 84 LKQIWNDYKLKWNPSGYGGAEFMRVPAQKIWKPDIVLYNNAV---GDFQVTTKTKALLKY 140
Query: 437 NGSVSWIKRLDISTPISMQLDNWXNDMQTCTFKFGSRMHNSDXMDXVI 580
G V+WI + + + + D Q CT KFGS ++ +D V+
Sbjct: 141 TGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVL 188
>BC014456-1|AAH14456.1| 494|Homo sapiens cholinergic receptor,
nicotinic, alpha 6 protein.
Length = 494
Score = 59.7 bits (138), Expect = 1e-08
Identities = 41/166 (24%), Positives = 76/166 (45%), Gaps = 10/166 (6%)
Frame = +2
Query: 113 CENATSLSLMIDSLLATYDRESPPDSKIVVNLTLHL-----RHANIRESESTVRILADLQ 277
C + + L + Y++ P + +T+H + AN+ E + L+
Sbjct: 28 CVGCATEERLFHKLFSHYNQFIRPVENVSDPVTVHFEVAITQLANVDEVNQIMETNLWLR 87
Query: 278 MNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNG 442
W D +L W+ E+ G T V ++++W+PD+VL N A GD+ + +A + NG
Sbjct: 88 HIWNDYKLRWDPMEYDGIETLRVPADKIWKPDIVLYNNAV---GDFQVEGKTKALLKYNG 144
Query: 443 SVSWIKRLDISTPISMQLDNWXNDMQTCTFKFGSRMHNSDXMDXVI 580
++W + M + + D Q C+ KFGS ++ +D +I
Sbjct: 145 MITWTPPAIFKSSCPMDITFFPFDHQNCSLKFGSWTYDKAEIDLLI 190
>AB079251-1|BAC06855.1| 494|Homo sapiens Nicotinic acetylcholine
receptor alpha 6 protein.
Length = 494
Score = 59.7 bits (138), Expect = 1e-08
Identities = 41/166 (24%), Positives = 76/166 (45%), Gaps = 10/166 (6%)
Frame = +2
Query: 113 CENATSLSLMIDSLLATYDRESPPDSKIVVNLTLHL-----RHANIRESESTVRILADLQ 277
C + + L + Y++ P + +T+H + AN+ E + L+
Sbjct: 28 CVGCATEERLFHKLFSHYNQFIRPVENVSDPVTVHFEVAITQLANVDEVNQIMETNLWLR 87
Query: 278 MNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNG 442
W D +L W+ E+ G T V ++++W+PD+VL N A GD+ + +A + NG
Sbjct: 88 HIWNDYKLRWDPMEYDGIETLRVPADKIWKPDIVLYNNAV---GDFQVEGKTKALLKYNG 144
Query: 443 SVSWIKRLDISTPISMQLDNWXNDMQTCTFKFGSRMHNSDXMDXVI 580
++W + M + + D Q C+ KFGS ++ +D +I
Sbjct: 145 MITWTPPAIFKSSCPMDITFFPFDHQNCSLKFGSWTYDKAEIDLLI 190
>X14830-1|CAA32939.1| 501|Homo sapiens protein ( Human mRNA for
muscle acetylcholine receptor beta-subunit. ).
Length = 501
Score = 59.3 bits (137), Expect = 2e-08
Identities = 45/134 (33%), Positives = 67/134 (50%), Gaps = 4/134 (2%)
Frame = +2
Query: 170 RESPPDSKIVVNLTL-HLRHANIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLV 343
RE ++ V L L L N ++ E + ++ DL+ W D RLSW+ E G + +
Sbjct: 46 REVGDRVRVSVGLILAQLISLNEKDEEMSTKVYLDLE--WTDYRLSWDPAEHDGIDSLRI 103
Query: 344 SSERLWRPDVVLLNAAATTAGDYAL--RARVSNNGSVSWIKRLDISTPISMQLDNWXNDM 517
++E +W PDVVLLN D AL VS++GSV W + S+Q+ + D
Sbjct: 104 TAESVWLPDVVLLNNNDGNF-DVALDISVVVSSDGSVRWQPPGIYRSSCSIQVTYFPFDW 162
Query: 518 QTCTFKFGSRMHNS 559
Q CT F S ++S
Sbjct: 163 QNCTMVFSSYSYDS 176
>BC011371-1|AAH11371.1| 501|Homo sapiens cholinergic receptor,
nicotinic, beta 1 (muscle) protein.
Length = 501
Score = 59.3 bits (137), Expect = 2e-08
Identities = 45/134 (33%), Positives = 67/134 (50%), Gaps = 4/134 (2%)
Frame = +2
Query: 170 RESPPDSKIVVNLTL-HLRHANIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLV 343
RE ++ V L L L N ++ E + ++ DL+ W D RLSW+ E G + +
Sbjct: 46 REVGDRVRVSVGLILAQLISLNEKDEEMSTKVYLDLE--WTDYRLSWDPAEHDGIDSLRI 103
Query: 344 SSERLWRPDVVLLNAAATTAGDYAL--RARVSNNGSVSWIKRLDISTPISMQLDNWXNDM 517
++E +W PDVVLLN D AL VS++GSV W + S+Q+ + D
Sbjct: 104 TAESVWLPDVVLLNNNDGNF-DVALDISVVVSSDGSVRWQPPGIYRSSCSIQVTYFPFDW 162
Query: 518 QTCTFKFGSRMHNS 559
Q CT F S ++S
Sbjct: 163 QNCTMVFSSYSYDS 176
>Y08421-1|CAA69698.1| 627|Homo sapiens nicotinic acetylcholine
receptor alpha4 subunit precursor protein.
Length = 627
Score = 58.4 bits (135), Expect = 3e-08
Identities = 42/156 (26%), Positives = 78/156 (50%), Gaps = 10/156 (6%)
Frame = +2
Query: 140 MIDSLLATYDRESPPDSKI--VVNLTLHLRHANIRESESTVRILAD---LQMNWIDKRLS 304
++ L + Y++ S P + I VV + L A + + + +++ ++ W D +L
Sbjct: 40 LLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLR 99
Query: 305 WNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNGSVSWIKRLD 469
W+ ++ T + + SE +WRPD+VL N A GD+A+ +A + ++G V W
Sbjct: 100 WDPADYENVTSIRIPSELIWRPDIVLYNNAD---GDFAVTHLTKAHLFHDGRVQWTPPAI 156
Query: 470 ISTPISMQLDNWXNDMQTCTFKFGSRMHNSDXMDXV 577
+ S+ + + D Q CT KFGS ++ +D V
Sbjct: 157 YKSSCSIDVTFFPFDQQNCTMKFGSWTYDKAKIDLV 192
>X89741-1|CAA61893.1| 627|Homo sapiens neuronal acetylcholine
receptor alpha-4 subunit protein.
Length = 627
Score = 58.4 bits (135), Expect = 3e-08
Identities = 42/156 (26%), Positives = 78/156 (50%), Gaps = 10/156 (6%)
Frame = +2
Query: 140 MIDSLLATYDRESPPDSKI--VVNLTLHLRHANIRESESTVRILAD---LQMNWIDKRLS 304
++ L + Y++ S P + I VV + L A + + + +++ ++ W D +L
Sbjct: 40 LLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLR 99
Query: 305 WNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNGSVSWIKRLD 469
W+ ++ T + + SE +WRPD+VL N A GD+A+ +A + ++G V W
Sbjct: 100 WDPADYENVTSIRIPSELIWRPDIVLYNNAD---GDFAVTHLTKAHLFHDGRVQWTPPAI 156
Query: 470 ISTPISMQLDNWXNDMQTCTFKFGSRMHNSDXMDXV 577
+ S+ + + D Q CT KFGS ++ +D V
Sbjct: 157 YKSSCSIDVTFFPFDQQNCTMKFGSWTYDKAKIDLV 192
>X87629-1|CAA60959.1| 602|Homo sapiens nicotinic acetylcholine
receptor protein.
Length = 602
Score = 58.4 bits (135), Expect = 3e-08
Identities = 42/156 (26%), Positives = 78/156 (50%), Gaps = 10/156 (6%)
Frame = +2
Query: 140 MIDSLLATYDRESPPDSKI--VVNLTLHLRHANIRESESTVRILAD---LQMNWIDKRLS 304
++ L + Y++ S P + I VV + L A + + + +++ ++ W D +L
Sbjct: 15 LLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLR 74
Query: 305 WNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNGSVSWIKRLD 469
W+ ++ T + + SE +WRPD+VL N A GD+A+ +A + ++G V W
Sbjct: 75 WDPADYENVTSIRIPSELIWRPDIVLYNNAD---GDFAVTHLTKAHLFHDGRVQWTPPAI 131
Query: 470 ISTPISMQLDNWXNDMQTCTFKFGSRMHNSDXMDXV 577
+ S+ + + D Q CT KFGS ++ +D V
Sbjct: 132 YKSSCSIDVTFFPFDQQNCTMKFGSWTYDKAKIDLV 167
>U62433-1|AAB40111.1| 627|Homo sapiens nicotinic acetylcholine
receptor alpha4 subunit precursor protein.
Length = 627
Score = 58.4 bits (135), Expect = 3e-08
Identities = 42/156 (26%), Positives = 78/156 (50%), Gaps = 10/156 (6%)
Frame = +2
Query: 140 MIDSLLATYDRESPPDSKI--VVNLTLHLRHANIRESESTVRILAD---LQMNWIDKRLS 304
++ L + Y++ S P + I VV + L A + + + +++ ++ W D +L
Sbjct: 40 LLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLR 99
Query: 305 WNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNGSVSWIKRLD 469
W+ ++ T + + SE +WRPD+VL N A GD+A+ +A + ++G V W
Sbjct: 100 WDPADYENVTSIRIPSELIWRPDIVLYNNAD---GDFAVTHLTKAHLFHDGRVQWTPPAI 156
Query: 470 ISTPISMQLDNWXNDMQTCTFKFGSRMHNSDXMDXV 577
+ S+ + + D Q CT KFGS ++ +D V
Sbjct: 157 YKSSCSIDVTFFPFDQQNCTMKFGSWTYDKAKIDLV 192
>L35901-1|AAA64743.1| 627|Homo sapiens nicotinic acetylcholine
receptor alpha 4 subunit protein.
Length = 627
Score = 58.4 bits (135), Expect = 3e-08
Identities = 42/156 (26%), Positives = 78/156 (50%), Gaps = 10/156 (6%)
Frame = +2
Query: 140 MIDSLLATYDRESPPDSKI--VVNLTLHLRHANIRESESTVRILAD---LQMNWIDKRLS 304
++ L + Y++ S P + I VV + L A + + + +++ ++ W D +L
Sbjct: 40 LLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLR 99
Query: 305 WNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNGSVSWIKRLD 469
W+ ++ T + + SE +WRPD+VL N A GD+A+ +A + ++G V W
Sbjct: 100 WDPADYENVTSIRIPSELIWRPDIVLYNNAD---GDFAVTHLTKAHLFHDGRVQWTPPAI 156
Query: 470 ISTPISMQLDNWXNDMQTCTFKFGSRMHNSDXMDXV 577
+ S+ + + D Q CT KFGS ++ +D V
Sbjct: 157 YKSSCSIDVTFFPFDQQNCTMKFGSWTYDKAKIDLV 192
>DQ093071-1|AAY88737.1| 627|Homo sapiens cholinergic receptor,
nicotinic, alpha polypeptide 4 protein.
Length = 627
Score = 58.4 bits (135), Expect = 3e-08
Identities = 42/156 (26%), Positives = 78/156 (50%), Gaps = 10/156 (6%)
Frame = +2
Query: 140 MIDSLLATYDRESPPDSKI--VVNLTLHLRHANIRESESTVRILAD---LQMNWIDKRLS 304
++ L + Y++ S P + I VV + L A + + + +++ ++ W D +L
Sbjct: 40 LLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLR 99
Query: 305 WNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNGSVSWIKRLD 469
W+ ++ T + + SE +WRPD+VL N A GD+A+ +A + ++G V W
Sbjct: 100 WDPADYENVTSIRIPSELIWRPDIVLYNNAD---GDFAVTHLTKAHLFHDGRVQWTPPAI 156
Query: 470 ISTPISMQLDNWXNDMQTCTFKFGSRMHNSDXMDXV 577
+ S+ + + D Q CT KFGS ++ +D V
Sbjct: 157 YKSSCSIDVTFFPFDQQNCTMKFGSWTYDKAKIDLV 192
>BC096290-1|AAH96290.1| 627|Homo sapiens cholinergic receptor,
nicotinic, alpha 4 protein.
Length = 627
Score = 58.4 bits (135), Expect = 3e-08
Identities = 42/156 (26%), Positives = 78/156 (50%), Gaps = 10/156 (6%)
Frame = +2
Query: 140 MIDSLLATYDRESPPDSKI--VVNLTLHLRHANIRESESTVRILAD---LQMNWIDKRLS 304
++ L + Y++ S P + I VV + L A + + + +++ ++ W D +L
Sbjct: 40 LLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLR 99
Query: 305 WNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNGSVSWIKRLD 469
W+ ++ T + + SE +WRPD+VL N A GD+A+ +A + ++G V W
Sbjct: 100 WDPADYENVTSIRIPSELIWRPDIVLYNNAD---GDFAVTHLTKAHLFHDGRVQWTPPAI 156
Query: 470 ISTPISMQLDNWXNDMQTCTFKFGSRMHNSDXMDXV 577
+ S+ + + D Q CT KFGS ++ +D V
Sbjct: 157 YKSSCSIDVTFFPFDQQNCTMKFGSWTYDKAKIDLV 192
>BC023553-1|AAH23553.1| 501|Homo sapiens cholinergic receptor,
nicotinic, beta 1 (muscle) protein.
Length = 501
Score = 58.0 bits (134), Expect = 4e-08
Identities = 43/136 (31%), Positives = 68/136 (50%), Gaps = 6/136 (4%)
Frame = +2
Query: 170 RESPPDSKIVVNLTL-HLRHANIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLV 343
RE ++ V L L L N ++ E + ++ DL+ W D RLSW+ E G + +
Sbjct: 46 REVGDRVRVSVGLILAQLISLNEKDEEMSTKVYLDLE--WTDYRLSWDPAEHDGIDSLRI 103
Query: 344 SSERLWRPDVVLLNAAATTAGDY----ALRARVSNNGSVSWIKRLDISTPISMQLDNWXN 511
++E +W PDVVLLN G++ + VS++GSV W + S+Q+ +
Sbjct: 104 TAESVWLPDVVLLN---NNDGNFYVALDISVVVSSDGSVRWQPPGIYRSSCSIQVTYFPF 160
Query: 512 DMQTCTFKFGSRMHNS 559
D Q CT F S ++S
Sbjct: 161 DWQNCTMVFSSYSYDS 176
>Y08415-1|CAA69692.1| 502|Homo sapiens nicotinic acetylcholine
receptor beta2 subunit precursor protein.
Length = 502
Score = 55.6 bits (128), Expect = 2e-07
Identities = 38/146 (26%), Positives = 64/146 (43%), Gaps = 3/146 (2%)
Frame = +2
Query: 194 IVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 367
+ V L + L ++ E E + L W D RL+W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 368 DVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWXNDMQTCTFKFGS 544
DVVL N A + A VS +GS+ W+ + +++ ++ D Q CT KF S
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRS 175
Query: 545 RMHNSDXMDXVIDKRIYRMFRVTSVG 622
++ +D V+ + + T G
Sbjct: 176 WTYDRTEIDLVLKSEVASLDDFTPSG 201
>X53179-1|CAA37320.1| 502|Homo sapiens precursor peptide (AA -25 to
477) protein.
Length = 502
Score = 55.6 bits (128), Expect = 2e-07
Identities = 38/146 (26%), Positives = 64/146 (43%), Gaps = 3/146 (2%)
Frame = +2
Query: 194 IVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 367
+ V L + L ++ E E + L W D RL+W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 368 DVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWXNDMQTCTFKFGS 544
DVVL N A + A VS +GS+ W+ + +++ ++ D Q CT KF S
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRS 175
Query: 545 RMHNSDXMDXVIDKRIYRMFRVTSVG 622
++ +D V+ + + T G
Sbjct: 176 WTYDRTEIDLVLKSEVASLDDFTPSG 201
>U62437-1|AAB40115.1| 502|Homo sapiens nicotinic acetylcholine
receptor beta2 subunit precursor protein.
Length = 502
Score = 55.6 bits (128), Expect = 2e-07
Identities = 38/146 (26%), Positives = 64/146 (43%), Gaps = 3/146 (2%)
Frame = +2
Query: 194 IVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 367
+ V L + L ++ E E + L W D RL+W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 368 DVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWXNDMQTCTFKFGS 544
DVVL N A + A VS +GS+ W+ + +++ ++ D Q CT KF S
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRS 175
Query: 545 RMHNSDXMDXVIDKRIYRMFRVTSVG 622
++ +D V+ + + T G
Sbjct: 176 WTYDRTEIDLVLKSEVASLDDFTPSG 201
>BC075041-1|AAH75041.1| 502|Homo sapiens cholinergic receptor,
nicotinic, beta 2 (neuronal) protein.
Length = 502
Score = 55.6 bits (128), Expect = 2e-07
Identities = 38/146 (26%), Positives = 64/146 (43%), Gaps = 3/146 (2%)
Frame = +2
Query: 194 IVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 367
+ V L + L ++ E E + L W D RL+W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 368 DVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWXNDMQTCTFKFGS 544
DVVL N A + A VS +GS+ W+ + +++ ++ D Q CT KF S
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRS 175
Query: 545 RMHNSDXMDXVIDKRIYRMFRVTSVG 622
++ +D V+ + + T G
Sbjct: 176 WTYDRTEIDLVLKSEVASLDDFTPSG 201
>BC075040-1|AAH75040.1| 502|Homo sapiens cholinergic receptor,
nicotinic, beta 2 (neuronal) protein.
Length = 502
Score = 55.6 bits (128), Expect = 2e-07
Identities = 38/146 (26%), Positives = 64/146 (43%), Gaps = 3/146 (2%)
Frame = +2
Query: 194 IVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 367
+ V L + L ++ E E + L W D RL+W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 368 DVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWXNDMQTCTFKFGS 544
DVVL N A + A VS +GS+ W+ + +++ ++ D Q CT KF S
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRS 175
Query: 545 RMHNSDXMDXVIDKRIYRMFRVTSVG 622
++ +D V+ + + T G
Sbjct: 176 WTYDRTEIDLVLKSEVASLDDFTPSG 201
>AL592078-3|CAI16184.1| 502|Homo sapiens cholinergic receptor,
nicotinic, beta 2 (neuronal) protein.
Length = 502
Score = 55.6 bits (128), Expect = 2e-07
Identities = 38/146 (26%), Positives = 64/146 (43%), Gaps = 3/146 (2%)
Frame = +2
Query: 194 IVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 367
+ V L + L ++ E E + L W D RL+W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 368 DVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWXNDMQTCTFKFGS 544
DVVL N A + A VS +GS+ W+ + +++ ++ D Q CT KF S
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRS 175
Query: 545 RMHNSDXMDXVIDKRIYRMFRVTSVG 622
++ +D V+ + + T G
Sbjct: 176 WTYDRTEIDLVLKSEVASLDDFTPSG 201
>AJ001935-1|CAA05108.1| 504|Homo sapiens CHRNB2 protein.
Length = 504
Score = 55.6 bits (128), Expect = 2e-07
Identities = 38/146 (26%), Positives = 64/146 (43%), Gaps = 3/146 (2%)
Frame = +2
Query: 194 IVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 367
+ V L + L ++ E E + L W D RL+W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 368 DVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWXNDMQTCTFKFGS 544
DVVL N A + A VS +GS+ W+ + +++ ++ D Q CT KF S
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRS 175
Query: 545 RMHNSDXMDXVIDKRIYRMFRVTSVG 622
++ +D V+ + + T G
Sbjct: 176 WTYDRTEIDLVLKSEVASLDDFTPSG 201
>AF077186-1|AAD45422.1| 502|Homo sapiens neuronal nicotinic
acetylcholine receptor beta 2 protein.
Length = 502
Score = 55.6 bits (128), Expect = 2e-07
Identities = 38/146 (26%), Positives = 64/146 (43%), Gaps = 3/146 (2%)
Frame = +2
Query: 194 IVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 367
+ V L + L ++ E E + L W D RL+W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 368 DVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWXNDMQTCTFKFGS 544
DVVL N A + A VS +GS+ W+ + +++ ++ D Q CT KF S
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRS 175
Query: 545 RMHNSDXMDXVIDKRIYRMFRVTSVG 622
++ +D V+ + + T G
Sbjct: 176 WTYDRTEIDLVLKSEVASLDDFTPSG 201
>X66403-1|CAA47030.1| 493|Homo sapiens acetylcholine receptor
epsilon subunit CHRNE protein.
Length = 493
Score = 55.2 bits (127), Expect = 3e-07
Identities = 33/133 (24%), Positives = 68/133 (51%), Gaps = 3/133 (2%)
Frame = +2
Query: 182 PDSKIVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEWG-CSTWLVSSER 355
P+ + ++L + L + ++ E E T+ + ++W D RL+++ ++G T V SE
Sbjct: 45 PEDTVTISLKVTLTNLISLNEKEETLTTSVWIGIDWQDYRLNYSKDDFGGIETLRVPSEL 104
Query: 356 LWRPDVVLLNAAATTAG-DYALRARVSNNGSVSWIKRLDISTPISMQLDNWXNDMQTCTF 532
+W P++VL N G Y V GSV+W+ + ++++ + D Q C+
Sbjct: 105 VWLPEIVLENNIDGQFGVAYDANVLVYEGGSVTWLPPAIYRSVCAVEVTYFPFDWQNCSL 164
Query: 533 KFGSRMHNSDXMD 571
F S+ +N++ ++
Sbjct: 165 IFRSQTYNAEEVE 177
>DQ644022-1|ABG35128.1| 456|Homo sapiens 5-HT3 receptor subunit E
splice variant HTR3Ea protein.
Length = 456
Score = 55.2 bits (127), Expect = 3e-07
Identities = 28/111 (25%), Positives = 55/111 (49%), Gaps = 1/111 (0%)
Frame = +2
Query: 272 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 448
L+M W + +SWN E G + ++++ LW PD+ ++ L A VSN G +
Sbjct: 91 LEMVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEGRI 150
Query: 449 SWIKRLDISTPISMQLDNWXNDMQTCTFKFGSRMHNSDXMDXVIDKRIYRM 601
+ K + + + ++ + + D Q CT F S ++ D M ++K ++ +
Sbjct: 151 RYKKPMKVDSICNLDIFYFPFDQQNCTLTFSSFLYTVDSMLLDMEKEVWEI 201
>BC131799-1|AAI31800.1| 447|Homo sapiens 5-hydroxytryptamine
(serotonin) receptor 3, family member C protein.
Length = 447
Score = 55.2 bits (127), Expect = 3e-07
Identities = 27/111 (24%), Positives = 56/111 (50%), Gaps = 1/111 (0%)
Frame = +2
Query: 272 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 448
+ + W + ++WN E G + V +E LW PD+ ++ + L A +S+ G +
Sbjct: 91 MDLVWDNPFINWNPKECVGINKLTVLAENLWLPDIFIVESMDVDQTPSGLTAYISSEGRI 150
Query: 449 SWIKRLDISTPISMQLDNWXNDMQTCTFKFGSRMHNSDXMDXVIDKRIYRM 601
+ K + +++ ++ + + D Q CTF F S ++ D M +DK ++ +
Sbjct: 151 KYDKPMRVTSICNLDIFYFPFDQQNCTFTFSSFLYTVDSMLLGMDKEVWEI 201
>BC101185-1|AAI01186.1| 374|Homo sapiens HTR3E protein protein.
Length = 374
Score = 55.2 bits (127), Expect = 3e-07
Identities = 28/111 (25%), Positives = 55/111 (49%), Gaps = 1/111 (0%)
Frame = +2
Query: 272 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 448
L+M W + +SWN E G + ++++ LW PD+ ++ L A VSN G +
Sbjct: 20 LEMVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEGRI 79
Query: 449 SWIKRLDISTPISMQLDNWXNDMQTCTFKFGSRMHNSDXMDXVIDKRIYRM 601
+ K + + + ++ + + D Q CT F S ++ D M ++K ++ +
Sbjct: 80 RYKKPMKVDSICNLDIFYFPFDQQNCTLTFSSFLYTVDSMLLDMEKEVWEI 130
>BC101183-1|AAI01184.1| 471|Homo sapiens 5-hydroxytryptamine
(serotonin) receptor 3, family member E protein.
Length = 471
Score = 55.2 bits (127), Expect = 3e-07
Identities = 28/111 (25%), Positives = 55/111 (49%), Gaps = 1/111 (0%)
Frame = +2
Query: 272 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 448
L+M W + +SWN E G + ++++ LW PD+ ++ L A VSN G +
Sbjct: 106 LEMVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEGRI 165
Query: 449 SWIKRLDISTPISMQLDNWXNDMQTCTFKFGSRMHNSDXMDXVIDKRIYRM 601
+ K + + + ++ + + D Q CT F S ++ D M ++K ++ +
Sbjct: 166 RYKKPMKVDSICNLDIFYFPFDQQNCTLTFSSFLYTVDSMLLDMEKEVWEI 216
>BC101182-1|AAI01183.1| 471|Homo sapiens 5-hydroxytryptamine
(serotonin) receptor 3, family member E protein.
Length = 471
Score = 55.2 bits (127), Expect = 3e-07
Identities = 28/111 (25%), Positives = 55/111 (49%), Gaps = 1/111 (0%)
Frame = +2
Query: 272 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 448
L+M W + +SWN E G + ++++ LW PD+ ++ L A VSN G +
Sbjct: 106 LEMVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEGRI 165
Query: 449 SWIKRLDISTPISMQLDNWXNDMQTCTFKFGSRMHNSDXMDXVIDKRIYRM 601
+ K + + + ++ + + D Q CT F S ++ D M ++K ++ +
Sbjct: 166 RYKKPMKVDSICNLDIFYFPFDQQNCTLTFSSFLYTVDSMLLDMEKEVWEI 216
>AY159813-1|AAO38167.2| 471|Homo sapiens 5-hydroxytryptamine
serotonin receptor 3E protein.
Length = 471
Score = 55.2 bits (127), Expect = 3e-07
Identities = 28/111 (25%), Positives = 55/111 (49%), Gaps = 1/111 (0%)
Frame = +2
Query: 272 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 448
L+M W + +SWN E G + ++++ LW PD+ ++ L A VSN G +
Sbjct: 106 LEMVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEGRI 165
Query: 449 SWIKRLDISTPISMQLDNWXNDMQTCTFKFGSRMHNSDXMDXVIDKRIYRM 601
+ K + + + ++ + + D Q CT F S ++ D M ++K ++ +
Sbjct: 166 RYKKPMKVDSICNLDIFYFPFDQQNCTLTFSSFLYTVDSMLLDMEKEVWEI 216
>AF105999-1|AAD24503.1| 493|Homo sapiens acetylcholine receptor
epsilon subunit protein.
Length = 493
Score = 55.2 bits (127), Expect = 3e-07
Identities = 33/133 (24%), Positives = 68/133 (51%), Gaps = 3/133 (2%)
Frame = +2
Query: 182 PDSKIVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEWG-CSTWLVSSER 355
P+ + ++L + L + ++ E E T+ + ++W D RL+++ ++G T V SE
Sbjct: 45 PEDTVTISLKVTLTNLISLNEKEETLTTSVWIGIDWQDYRLNYSKDDFGGIETLRVPSEL 104
Query: 356 LWRPDVVLLNAAATTAG-DYALRARVSNNGSVSWIKRLDISTPISMQLDNWXNDMQTCTF 532
+W P++VL N G Y V GSV+W+ + ++++ + D Q C+
Sbjct: 105 VWLPEIVLENNIDGQFGVAYDANVLVYEGGSVTWLPPAIYRSVCAVEVTYFPFDWQNCSL 164
Query: 533 KFGSRMHNSDXMD 571
F S+ +N++ ++
Sbjct: 165 IFRSQTYNAEEVE 177
>X01715-1|CAA25861.1| 520|Homo sapiens acetylcholine receptor gamma
chain precursor protein.
Length = 520
Score = 54.8 bits (126), Expect = 4e-07
Identities = 41/152 (26%), Positives = 71/152 (46%), Gaps = 8/152 (5%)
Frame = +2
Query: 140 MIDSLLATYDRESPPDSKI--VVNLTLHLRHANI---RESESTVRILADLQMNWIDKRLS 304
++ L+ YD P + VVN++L L N+ E E + ++M W D RL
Sbjct: 32 LLADLMQNYDPNLRPAERDSDVVNVSLKLTLTNLISLNEREEALTTNVWIEMQWCDYRLR 91
Query: 305 WNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARV--SNNGSVSWIKRLDIS 475
W+ ++ G V S +WRPD+VL N + AL V S +G + W+
Sbjct: 92 WDPRDYEGLWVLRVPSTMVWRPDIVLENNVDGVF-EVALYCNVLVSPDGCIYWLPPAIFR 150
Query: 476 TPISMQLDNWXNDMQTCTFKFGSRMHNSDXMD 571
+ S+ + + D Q C+ F S+ ++++ +D
Sbjct: 151 SACSISVTYFPFDWQNCSLIFQSQTYSTNEID 182
>BC113575-1|AAI13576.1| 479|Homo sapiens cholinergic receptor,
nicotinic, alpha 9 protein.
Length = 479
Score = 54.8 bits (126), Expect = 4e-07
Identities = 38/163 (23%), Positives = 74/163 (45%), Gaps = 7/163 (4%)
Frame = +2
Query: 104 AAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHANIRESESTVRILAD-- 271
AAE + + + L Y P D+ V+N+TL + + I++ + +IL
Sbjct: 22 AAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQITLSQIKDMDERNQILTAYL 81
Query: 272 -LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGD-YALRARVSNNG 442
++ W D L+W+ ++ G + + S+ +WRPD+VL N A + + + +G
Sbjct: 82 WIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKADDESSEPVNTNVVLRYDG 141
Query: 443 SVSWIKRLDISTPISMQLDNWXNDMQTCTFKFGSRMHNSDXMD 571
++W + + + + D Q C FGS +N + +D
Sbjct: 142 LITWDAPAITKSSCVVDVTYFPFDNQQCNLTFGSWTYNGNQVD 184
>BC113549-1|AAI13550.1| 479|Homo sapiens cholinergic receptor,
nicotinic, alpha 9 protein.
Length = 479
Score = 54.8 bits (126), Expect = 4e-07
Identities = 38/163 (23%), Positives = 74/163 (45%), Gaps = 7/163 (4%)
Frame = +2
Query: 104 AAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHANIRESESTVRILAD-- 271
AAE + + + L Y P D+ V+N+TL + + I++ + +IL
Sbjct: 22 AAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQITLSQIKDMDERNQILTAYL 81
Query: 272 -LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGD-YALRARVSNNG 442
++ W D L+W+ ++ G + + S+ +WRPD+VL N A + + + +G
Sbjct: 82 WIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKADDESSEPVNTNVVLRYDG 141
Query: 443 SVSWIKRLDISTPISMQLDNWXNDMQTCTFKFGSRMHNSDXMD 571
++W + + + + D Q C FGS +N + +D
Sbjct: 142 LITWDAPAITKSSCVVDVTYFPFDNQQCNLTFGSWTYNGNQVD 184
>AY123244-1|AAM74523.1| 479|Homo sapiens nicotinic acetylcholine
receptor subunit alpha 9 protein.
Length = 479
Score = 54.8 bits (126), Expect = 4e-07
Identities = 38/163 (23%), Positives = 74/163 (45%), Gaps = 7/163 (4%)
Frame = +2
Query: 104 AAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHANIRESESTVRILAD-- 271
AAE + + + L Y P D+ V+N+TL + + I++ + +IL
Sbjct: 22 AAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQITLSQIKDMDERNQILTAYL 81
Query: 272 -LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGD-YALRARVSNNG 442
++ W D L+W+ ++ G + + S+ +WRPD+VL N A + + + +G
Sbjct: 82 WIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKADDESSEPVNTNVVLRYDG 141
Query: 443 SVSWIKRLDISTPISMQLDNWXNDMQTCTFKFGSRMHNSDXMD 571
++W + + + + D Q C FGS +N + +D
Sbjct: 142 LITWDAPAITKSSCVVDVTYFPFDNQQCNLTFGSWTYNGNQVD 184
>AJ243342-1|CAB65091.1| 479|Homo sapiens nicotinic acetylcholine
receptor alpha 9 subunit protein.
Length = 479
Score = 54.8 bits (126), Expect = 4e-07
Identities = 38/163 (23%), Positives = 74/163 (45%), Gaps = 7/163 (4%)
Frame = +2
Query: 104 AAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHANIRESESTVRILAD-- 271
AAE + + + L Y P D+ V+N+TL + + I++ + +IL
Sbjct: 22 AAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQITLSQIKDMDERNQILTAYL 81
Query: 272 -LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGD-YALRARVSNNG 442
++ W D L+W+ ++ G + + S+ +WRPD+VL N A + + + +G
Sbjct: 82 WIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKADDESSEPVNTNVVLRYDG 141
Query: 443 SVSWIKRLDISTPISMQLDNWXNDMQTCTFKFGSRMHNSDXMD 571
++W + + + + D Q C FGS +N + +D
Sbjct: 142 LITWDAPAITKSSCVVDVTYFPFDNQQCNLTFGSWTYNGNQVD 184
>AF459285-1|AAL66182.1| 447|Homo sapiens 5-hydroxytryptamine
receptor 3 subunit C protein.
Length = 447
Score = 54.8 bits (126), Expect = 4e-07
Identities = 27/111 (24%), Positives = 55/111 (49%), Gaps = 1/111 (0%)
Frame = +2
Query: 272 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 448
+ + W + ++WN E G + V +E LW PD+ ++ + L A +S+ G +
Sbjct: 91 MDLVWDNPFINWNPKECVGINKLTVLAENLWLPDIFIVESMDVDQTPSGLTAYISSEGRI 150
Query: 449 SWIKRLDISTPISMQLDNWXNDMQTCTFKFGSRMHNSDXMDXVIDKRIYRM 601
+ K + +++ + + + D Q CTF F S ++ D M +DK ++ +
Sbjct: 151 KYDKPMRVTSICKLDIFYFPFDQQNCTFTFSSFLYTVDSMLLGMDKEVWEI 201
>AF227732-1|AAF61920.1| 470|Homo sapiens nicotinic acetylcholine
receptor alpha 9 subunit protein.
Length = 470
Score = 54.8 bits (126), Expect = 4e-07
Identities = 38/163 (23%), Positives = 74/163 (45%), Gaps = 7/163 (4%)
Frame = +2
Query: 104 AAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHANIRESESTVRILAD-- 271
AAE + + + L Y P D+ V+N+TL + + I++ + +IL
Sbjct: 16 AAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQITLSQIKDMDERNQILTAYL 75
Query: 272 -LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGD-YALRARVSNNG 442
++ W D L+W+ ++ G + + S+ +WRPD+VL N A + + + +G
Sbjct: 76 WIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKADDESSEPVNTNVVLRYDG 135
Query: 443 SVSWIKRLDISTPISMQLDNWXNDMQTCTFKFGSRMHNSDXMD 571
++W + + + + D Q C FGS +N + +D
Sbjct: 136 LITWDAPAITKSSCVVDVTYFPFDNQQCNLTFGSWTYNGNQVD 178
>AC118275-1|AAY40986.1| 479|Homo sapiens unknown protein.
Length = 479
Score = 54.8 bits (126), Expect = 4e-07
Identities = 38/163 (23%), Positives = 74/163 (45%), Gaps = 7/163 (4%)
Frame = +2
Query: 104 AAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHANIRESESTVRILAD-- 271
AAE + + + L Y P D+ V+N+TL + + I++ + +IL
Sbjct: 22 AAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQITLSQIKDMDERNQILTAYL 81
Query: 272 -LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGD-YALRARVSNNG 442
++ W D L+W+ ++ G + + S+ +WRPD+VL N A + + + +G
Sbjct: 82 WIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKADDESSEPVNTNVVLRYDG 141
Query: 443 SVSWIKRLDISTPISMQLDNWXNDMQTCTFKFGSRMHNSDXMD 571
++W + + + + D Q C FGS +N + +D
Sbjct: 142 LITWDAPAITKSSCVVDVTYFPFDNQQCNLTFGSWTYNGNQVD 184
>AC092165-3|AAY24103.1| 520|Homo sapiens unknown protein.
Length = 520
Score = 54.8 bits (126), Expect = 4e-07
Identities = 41/152 (26%), Positives = 71/152 (46%), Gaps = 8/152 (5%)
Frame = +2
Query: 140 MIDSLLATYDRESPPDSKI--VVNLTLHLRHANI---RESESTVRILADLQMNWIDKRLS 304
++ L+ YD P + VVN++L L N+ E E + ++M W D RL
Sbjct: 32 LLADLMQNYDPNLRPAERDSDVVNVSLKLTLTNLISLNEREEALTTNVWIEMQWCDYRLR 91
Query: 305 WNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARV--SNNGSVSWIKRLDIS 475
W+ ++ G V S +WRPD+VL N + AL V S +G + W+
Sbjct: 92 WDPRDYEGLWVLRVPSTMVWRPDIVLENNVDGVF-EVALYCNVLVSPDGCIYWLPPAIFR 150
Query: 476 TPISMQLDNWXNDMQTCTFKFGSRMHNSDXMD 571
+ S+ + + D Q C+ F S+ ++++ +D
Sbjct: 151 SACSISVTYFPFDWQNCSLIFQSQTYSTNEID 182
>Y00762-1|CAA68731.1| 457|Homo sapiens protein ( Human mRNA for
muscle acetylcholine receptor alpha-subunit. ).
Length = 457
Score = 54.4 bits (125), Expect = 5e-07
Identities = 33/123 (26%), Positives = 60/123 (48%), Gaps = 5/123 (4%)
Frame = +2
Query: 191 KIVVNLTLHLRHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRP 367
++ V L L ++ N+ E V L+ W+D L WN ++G + + SE++WRP
Sbjct: 50 EVTVGLQL-IQLINVDEVNQIVTTNVRLKQQWVDYNLKWNPDDYGGVKKIHIPSEKIWRP 108
Query: 368 DVVLLNAAATTAGDYAL----RARVSNNGSVSWIKRLDISTPISMQLDNWXNDMQTCTFK 535
D+VL N A GD+A+ + + G ++W + + + ++ D Q C+ K
Sbjct: 109 DLVLYNNA---DGDFAIVKFTKVLLQYTGHITWTPPAIFKSYCEIIVTHFPFDEQNCSMK 165
Query: 536 FGS 544
G+
Sbjct: 166 LGT 168
>X02502-1|CAA26344.1| 457|Homo sapiens acetylcholine receptor
protein.
Length = 457
Score = 54.4 bits (125), Expect = 5e-07
Identities = 33/123 (26%), Positives = 60/123 (48%), Gaps = 5/123 (4%)
Frame = +2
Query: 191 KIVVNLTLHLRHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRP 367
++ V L L ++ N+ E V L+ W+D L WN ++G + + SE++WRP
Sbjct: 50 EVTVGLQL-IQLINVDEVNQIVTTNVRLKQQWVDYNLKWNPDDYGGVKKIHIPSEKIWRP 108
Query: 368 DVVLLNAAATTAGDYAL----RARVSNNGSVSWIKRLDISTPISMQLDNWXNDMQTCTFK 535
D+VL N A GD+A+ + + G ++W + + + ++ D Q C+ K
Sbjct: 109 DLVLYNNA---DGDFAIVKFTKVLLQYTGHITWTPPAIFKSYCEIIVTHFPFDEQNCSMK 165
Query: 536 FGS 544
G+
Sbjct: 166 LGT 168
>S77094-1|AAD14247.1| 457|Homo sapiens nicotinic acetylcholine
receptor alpha subunit|AChR protein.
Length = 457
Score = 54.4 bits (125), Expect = 5e-07
Identities = 33/123 (26%), Positives = 60/123 (48%), Gaps = 5/123 (4%)
Frame = +2
Query: 191 KIVVNLTLHLRHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRP 367
++ V L L ++ N+ E V L+ W+D L WN ++G + + SE++WRP
Sbjct: 50 EVTVGLQL-IQLINVDEVNQIVTTNVRLKQQWVDYNLKWNPDDYGGVKKIHIPSEKIWRP 108
Query: 368 DVVLLNAAATTAGDYAL----RARVSNNGSVSWIKRLDISTPISMQLDNWXNDMQTCTFK 535
D+VL N A GD+A+ + + G ++W + + + ++ D Q C+ K
Sbjct: 109 DLVLYNNA---DGDFAIVKFTKVLLQYTGHITWTPPAIFKSYCEIIVTHFPFDEQNCSMK 165
Query: 536 FGS 544
G+
Sbjct: 166 LGT 168
>BC006314-1|AAH06314.1| 269|Homo sapiens CHRNA1 protein protein.
Length = 269
Score = 54.4 bits (125), Expect = 5e-07
Identities = 33/123 (26%), Positives = 60/123 (48%), Gaps = 5/123 (4%)
Frame = +2
Query: 191 KIVVNLTLHLRHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRP 367
++ V L L ++ N+ E V L+ W+D L WN ++G + + SE++WRP
Sbjct: 50 EVTVGLQL-IQLINVDEVNQIVTTNVRLKQQWVDYNLKWNPDDYGGVKKIHIPSEKIWRP 108
Query: 368 DVVLLNAAATTAGDYAL----RARVSNNGSVSWIKRLDISTPISMQLDNWXNDMQTCTFK 535
D+VL N A GD+A+ + + G ++W + + + ++ D Q C+ K
Sbjct: 109 DLVLYNNA---DGDFAIVKFTKVLLQYTGHITWTPPAIFKSYCEIIVTHFPFDEQNCSMK 165
Query: 536 FGS 544
G+
Sbjct: 166 LGT 168
>AC018890-1|AAY14687.1| 457|Homo sapiens unknown protein.
Length = 457
Score = 54.4 bits (125), Expect = 5e-07
Identities = 33/123 (26%), Positives = 60/123 (48%), Gaps = 5/123 (4%)
Frame = +2
Query: 191 KIVVNLTLHLRHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRP 367
++ V L L ++ N+ E V L+ W+D L WN ++G + + SE++WRP
Sbjct: 50 EVTVGLQL-IQLINVDEVNQIVTTNVRLKQQWVDYNLKWNPDDYGGVKKIHIPSEKIWRP 108
Query: 368 DVVLLNAAATTAGDYAL----RARVSNNGSVSWIKRLDISTPISMQLDNWXNDMQTCTFK 535
D+VL N A GD+A+ + + G ++W + + + ++ D Q C+ K
Sbjct: 109 DLVLYNNA---DGDFAIVKFTKVLLQYTGHITWTPPAIFKSYCEIIVTHFPFDEQNCSMK 165
Query: 536 FGS 544
G+
Sbjct: 166 LGT 168
>AJ295237-1|CAC16144.1| 450|Homo sapiens neuronal nicotinic
acetylcholine receptor subunit4 protein.
Length = 450
Score = 54.0 bits (124), Expect = 6e-07
Identities = 44/165 (26%), Positives = 71/165 (43%), Gaps = 10/165 (6%)
Frame = +2
Query: 107 AEC---ENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHANIRESESTVRILAD 271
AEC E +L L D L A Y P D+ +N+TL + + I + + ++L
Sbjct: 20 AECLGAEGRLALKLFRD-LFANYTSALRPVADTDQTLNVTLEVTLSQIIDMDERNQVLTL 78
Query: 272 ---LQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSN 436
++ W D L W+ +G + S +WRPD+VL N A A G + + +
Sbjct: 79 YLWIRQEWTDAYLRWDPNAYGGLDAIRIPSSLVWRPDIVLYNKADAQPPGSASTNVVLRH 138
Query: 437 NGSVSWIKRLDISTPISMQLDNWXNDMQTCTFKFGSRMHNSDXMD 571
+G+V W + + + + D Q C FGS H +D
Sbjct: 139 DGAVRWDAPAITRSSCRVDVAAFPFDAQHCGLTFGSWTHGGHQLD 183
>AJ278118-1|CAC20435.1| 450|Homo sapiens neuronal nicotinic
acetylcholine alpha10 subunit protein.
Length = 450
Score = 54.0 bits (124), Expect = 6e-07
Identities = 44/165 (26%), Positives = 71/165 (43%), Gaps = 10/165 (6%)
Frame = +2
Query: 107 AEC---ENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHANIRESESTVRILAD 271
AEC E +L L D L A Y P D+ +N+TL + + I + + ++L
Sbjct: 20 AECLGAEGRLALKLFRD-LFANYTSALRPVADTDQTLNVTLEVTLSQIIDMDERNQVLTL 78
Query: 272 ---LQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSN 436
++ W D L W+ +G + S +WRPD+VL N A A G + + +
Sbjct: 79 YLWIRQEWTDAYLRWDPNAYGGLDAIRIPSSLVWRPDIVLYNKADAQPPGSASTNVVLRH 138
Query: 437 NGSVSWIKRLDISTPISMQLDNWXNDMQTCTFKFGSRMHNSDXMD 571
+G+V W + + + + D Q C FGS H +D
Sbjct: 139 DGAVRWDAPAITRSSCRVDVAAFPFDAQHCGLTFGSWTHGGHQLD 183
>AF327367-1|AAK14333.1| 450|Homo sapiens nicotinic acetylcholine
receptor subunit alpha 10 protein.
Length = 450
Score = 54.0 bits (124), Expect = 6e-07
Identities = 44/165 (26%), Positives = 71/165 (43%), Gaps = 10/165 (6%)
Frame = +2
Query: 107 AEC---ENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHANIRESESTVRILAD 271
AEC E +L L D L A Y P D+ +N+TL + + I + + ++L
Sbjct: 20 AECLGAEGRLALKLFRD-LFANYTSALRPVADTDQTLNVTLEVTLSQIIDMDERNQVLTL 78
Query: 272 ---LQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSN 436
++ W D L W+ +G + S +WRPD+VL N A A G + + +
Sbjct: 79 YLWIRQEWTDAYLRWDPNAYGGLDAIRIPSSLVWRPDIVLYNKADAQPPGSASTNVVLRH 138
Query: 437 NGSVSWIKRLDISTPISMQLDNWXNDMQTCTFKFGSRMHNSDXMD 571
+G+V W + + + + D Q C FGS H +D
Sbjct: 139 DGAVRWDAPAITRSSCRVDVAAFPFDAQHCGLTFGSWTHGGHQLD 183
>AF199235-1|AAG00795.2| 450|Homo sapiens nicotinic acetylcholine
receptor subunit alpha 10 protein.
Length = 450
Score = 54.0 bits (124), Expect = 6e-07
Identities = 44/165 (26%), Positives = 71/165 (43%), Gaps = 10/165 (6%)
Frame = +2
Query: 107 AEC---ENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHANIRESESTVRILAD 271
AEC E +L L D L A Y P D+ +N+TL + + I + + ++L
Sbjct: 20 AECLGAEGRLALKLFRD-LFANYTSALRPVADTDQTLNVTLEVTLSQIIDMDERNQVLTL 78
Query: 272 ---LQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSN 436
++ W D L W+ +G + S +WRPD+VL N A A G + + +
Sbjct: 79 YLWIRQEWTDAYLRWDPNAYGGLDAIRIPSSLVWRPDIVLYNKADAQPPGSASTNVVLRH 138
Query: 437 NGSVSWIKRLDISTPISMQLDNWXNDMQTCTFKFGSRMHNSDXMD 571
+G+V W + + + + D Q C FGS H +D
Sbjct: 139 DGAVRWDAPAITRSSCRVDVAAFPFDAQHCGLTFGSWTHGGHQLD 183
>AY349353-1|AAQ93477.1| 456|Homo sapiens 5-HT3c1 serotonin
receptor-like protein protein.
Length = 456
Score = 53.2 bits (122), Expect = 1e-06
Identities = 28/113 (24%), Positives = 55/113 (48%), Gaps = 1/113 (0%)
Frame = +2
Query: 266 ADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNG 442
A L + W + +SWN E G + ++++ LW PD+ ++ L A VSN G
Sbjct: 89 AILDVVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEG 148
Query: 443 SVSWIKRLDISTPISMQLDNWXNDMQTCTFKFGSRMHNSDXMDXVIDKRIYRM 601
+ + K + + + ++ + + D Q CT F S ++ D M ++K ++ +
Sbjct: 149 RIRYKKPMKVDSICNLDIFYFPFDQQNCTLTFSSFLYTVDSMLLDMEKEVWEI 201
>AY349352-1|AAQ93476.1| 441|Homo sapiens 5-HT3c1 serotonin
receptor-like protein protein.
Length = 441
Score = 53.2 bits (122), Expect = 1e-06
Identities = 28/113 (24%), Positives = 55/113 (48%), Gaps = 1/113 (0%)
Frame = +2
Query: 266 ADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNG 442
A L + W + +SWN E G + ++++ LW PD+ ++ L A VSN G
Sbjct: 74 AILDVVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEG 133
Query: 443 SVSWIKRLDISTPISMQLDNWXNDMQTCTFKFGSRMHNSDXMDXVIDKRIYRM 601
+ + K + + + ++ + + D Q CT F S ++ D M ++K ++ +
Sbjct: 134 RIRYKKPMKVDSICNLDIFYFPFDQQNCTLTFSSFLYTVDSMLLDMEKEVWEI 186
>X55019-1|CAA38759.1| 517|Homo sapiens acetylcholine receptor delta
subunit protein.
Length = 517
Score = 51.2 bits (117), Expect = 5e-06
Identities = 36/134 (26%), Positives = 62/134 (46%), Gaps = 7/134 (5%)
Frame = +2
Query: 164 YDRESPP----DSKIVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEWG- 325
Y++E P + + V L L L + +++E E T+ ++ W D RL WNA E+G
Sbjct: 38 YNKELRPVAHKEESVDVALALTLSNLISLKEVEETLTTNVWIEHGWTDNRLKWNAEEFGN 97
Query: 326 CSTWLVSSERLWRPDVVL-LNAAATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDN 502
S + + +W P++VL N + Y+ V + G V W+ + + +
Sbjct: 98 ISVLRLPPDMVWLPEIVLENNNDGSFQISYSCNVLVYHYGFVYWLPPAIFRSSCPISVTY 157
Query: 503 WXNDMQTCTFKFGS 544
+ D Q C+ KF S
Sbjct: 158 FPFDWQNCSLKFSS 171
>BC093925-1|AAH93925.1| 517|Homo sapiens cholinergic receptor,
nicotinic, delta protein.
Length = 517
Score = 51.2 bits (117), Expect = 5e-06
Identities = 36/134 (26%), Positives = 62/134 (46%), Gaps = 7/134 (5%)
Frame = +2
Query: 164 YDRESPP----DSKIVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEWG- 325
Y++E P + + V L L L + +++E E T+ ++ W D RL WNA E+G
Sbjct: 38 YNKELRPVAHKEESVDVALALTLSNLISLKEVEETLTTNVWIEHGWTDNRLKWNAEEFGN 97
Query: 326 CSTWLVSSERLWRPDVVL-LNAAATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDN 502
S + + +W P++VL N + Y+ V + G V W+ + + +
Sbjct: 98 ISVLRLPPDMVWLPEIVLENNNDGSFQISYSCNVLVYHYGFVYWLPPAIFRSSCPISVTY 157
Query: 503 WXNDMQTCTFKFGS 544
+ D Q C+ KF S
Sbjct: 158 FPFDWQNCSLKFSS 171
>BC093923-1|AAH93923.1| 517|Homo sapiens cholinergic receptor,
nicotinic, delta protein.
Length = 517
Score = 51.2 bits (117), Expect = 5e-06
Identities = 36/134 (26%), Positives = 62/134 (46%), Gaps = 7/134 (5%)
Frame = +2
Query: 164 YDRESPP----DSKIVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEWG- 325
Y++E P + + V L L L + +++E E T+ ++ W D RL WNA E+G
Sbjct: 38 YNKELRPVAHKEESVDVALALTLSNLISLKEVEETLTTNVWIEHGWTDNRLKWNAEEFGN 97
Query: 326 CSTWLVSSERLWRPDVVL-LNAAATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDN 502
S + + +W P++VL N + Y+ V + G V W+ + + +
Sbjct: 98 ISVLRLPPDMVWLPEIVLENNNDGSFQISYSCNVLVYHYGFVYWLPPAIFRSSCPISVTY 157
Query: 503 WXNDMQTCTFKFGS 544
+ D Q C+ KF S
Sbjct: 158 FPFDWQNCSLKFSS 171
>AC092165-2|AAY24102.1| 517|Homo sapiens unknown protein.
Length = 517
Score = 51.2 bits (117), Expect = 5e-06
Identities = 36/134 (26%), Positives = 62/134 (46%), Gaps = 7/134 (5%)
Frame = +2
Query: 164 YDRESPP----DSKIVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEWG- 325
Y++E P + + V L L L + +++E E T+ ++ W D RL WNA E+G
Sbjct: 38 YNKELRPVAHKEESVDVALALTLSNLISLKEVEETLTTNVWIEHGWTDNRLKWNAEEFGN 97
Query: 326 CSTWLVSSERLWRPDVVL-LNAAATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDN 502
S + + +W P++VL N + Y+ V + G V W+ + + +
Sbjct: 98 ISVLRLPPDMVWLPEIVLENNNDGSFQISYSCNVLVYHYGFVYWLPPAIFRSSCPISVTY 157
Query: 503 WXNDMQTCTFKFGS 544
+ D Q C+ KF S
Sbjct: 158 FPFDWQNCSLKFSS 171
>BC111802-1|AAI11803.1| 465|Homo sapiens CHRNG protein protein.
Length = 465
Score = 49.6 bits (113), Expect = 1e-05
Identities = 33/113 (29%), Positives = 54/113 (47%), Gaps = 7/113 (6%)
Frame = +2
Query: 140 MIDSLLATYDRESPPDSKI--VVNLTLHLRHANI---RESESTVRILADLQMNWIDKRLS 304
++ L+ YD P + VVN++L L N+ E E + ++M W D RL
Sbjct: 29 LLADLMQNYDPNLRPAERDSDVVNVSLKLTLTNLISLNEREEALTTNVWIEMQWCDYRLR 88
Query: 305 WNAGEW-GCSTWLVSSERLWRPDVVLLNAAAT-TAGDYALRARVSNNGSVSWI 457
W+ ++ G V S +WRPD+VL N + T + + L+ + S+ WI
Sbjct: 89 WDPRDYEGLWVLRVPSTMVWRPDIVLENKSQTYSTNEIDLQLSQEDGQSIEWI 141
>Z23141-1|CAA80672.1| 479|Homo sapiens cholinergic receptor,
nicotinic, alpha polypeptide 7 protein.
Length = 479
Score = 47.6 bits (108), Expect = 6e-05
Identities = 27/102 (26%), Positives = 48/102 (47%), Gaps = 2/102 (1%)
Frame = +2
Query: 272 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSNNGS 445
LQM+W D L WN E+ G T ++W+PD++L N+A + V+++G
Sbjct: 55 LQMSWTDHYLQWNVSEYPGVKTVRFPDGQIWKPDILLYNSADERFDATFHTNVLVNSSGH 114
Query: 446 VSWIKRLDISTPISMQLDNWXNDMQTCTFKFGSRMHNSDXMD 571
++ + + + + D+Q C KFGS + +D
Sbjct: 115 CQYLPPGIFKSSCYIDVRWFPFDVQHCKLKFGSWSYGGWSLD 156
>Y08420-1|CAA69697.1| 502|Homo sapiens nicotinic acetylcholine
receptor alpha7 subunit precursor protein.
Length = 502
Score = 47.6 bits (108), Expect = 6e-05
Identities = 27/102 (26%), Positives = 48/102 (47%), Gaps = 2/102 (1%)
Frame = +2
Query: 272 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSNNGS 445
LQM+W D L WN E+ G T ++W+PD++L N+A + V+++G
Sbjct: 78 LQMSWTDHYLQWNVSEYPGVKTVRFPDGQIWKPDILLYNSADERFDATFHTNVLVNSSGH 137
Query: 446 VSWIKRLDISTPISMQLDNWXNDMQTCTFKFGSRMHNSDXMD 571
++ + + + + D+Q C KFGS + +D
Sbjct: 138 CQYLPPGIFKSSCYIDVRWFPFDVQHCKLKFGSWSYGGWSLD 179
>X70297-1|CAA49778.1| 502|Homo sapiens neuronal nicotinic
acetylocholine receptor alpha-7 subunit protein.
Length = 502
Score = 47.6 bits (108), Expect = 6e-05
Identities = 27/102 (26%), Positives = 48/102 (47%), Gaps = 2/102 (1%)
Frame = +2
Query: 272 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSNNGS 445
LQM+W D L WN E+ G T ++W+PD++L N+A + V+++G
Sbjct: 78 LQMSWTDHYLQWNVSEYPGVKTVRFPDGQIWKPDILLYNSADERFDATFHTNVLVNSSGH 137
Query: 446 VSWIKRLDISTPISMQLDNWXNDMQTCTFKFGSRMHNSDXMD 571
++ + + + + D+Q C KFGS + +D
Sbjct: 138 CQYLPPGIFKSSCYIDVRWFPFDVQHCKLKFGSWSYGGWSLD 179
>U62436-1|AAB40114.1| 502|Homo sapiens nicotinic acetylcholine
receptor alpha7 subunit precursor protein.
Length = 502
Score = 47.6 bits (108), Expect = 6e-05
Identities = 27/102 (26%), Positives = 48/102 (47%), Gaps = 2/102 (1%)
Frame = +2
Query: 272 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSNNGS 445
LQM+W D L WN E+ G T ++W+PD++L N+A + V+++G
Sbjct: 78 LQMSWTDHYLQWNVSEYPGVKTVRFPDGQIWKPDILLYNSADERFDATFHTNVLVNSSGH 137
Query: 446 VSWIKRLDISTPISMQLDNWXNDMQTCTFKFGSRMHNSDXMD 571
++ + + + + D+Q C KFGS + +D
Sbjct: 138 CQYLPPGIFKSSCYIDVRWFPFDVQHCKLKFGSWSYGGWSLD 179
>L08485-1|AAA58490.1| 462|Homo sapiens GABA-benzodiazepine receptor
alpha-5-subunit protein.
Length = 462
Score = 47.6 bits (108), Expect = 6e-05
Identities = 36/150 (24%), Positives = 66/150 (44%), Gaps = 7/150 (4%)
Frame = +2
Query: 116 ENATSLSLMIDSLLATYDRESPPD--SKIV-VNLTLHLRHAN-IRESESTVRILADLQMN 283
+N T + ++D LL YD P +I V +++ + ++E I + +
Sbjct: 44 DNITIFTRILDGLLDGYDNRLRPGLGERITQVRTDIYVTSFGPVSDTEMEYTIDVFFRQS 103
Query: 284 WIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSW 454
W D+RL + + + ++W PD N + A + R+ ++G++ +
Sbjct: 104 WKDERLRFKGPMQRLPLNNLLASKIWTPDTFFHNGKKSIAHNMTTPNKLLRLEDDGTLLY 163
Query: 455 IKRLDISTPISMQLDNWXNDMQTCTFKFGS 544
RL IS MQL+++ D C KFGS
Sbjct: 164 TMRLTISAECPMQLEDFPMDAHACPLKFGS 193
>BT009830-1|AAP88832.1| 462|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 5 protein.
Length = 462
Score = 47.6 bits (108), Expect = 6e-05
Identities = 36/150 (24%), Positives = 66/150 (44%), Gaps = 7/150 (4%)
Frame = +2
Query: 116 ENATSLSLMIDSLLATYDRESPPD--SKIV-VNLTLHLRHAN-IRESESTVRILADLQMN 283
+N T + ++D LL YD P +I V +++ + ++E I + +
Sbjct: 44 DNITIFTRILDGLLDGYDNRLRPGLGERITQVRTDIYVTSFGPVSDTEMEYTIDVFFRQS 103
Query: 284 WIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSW 454
W D+RL + + + ++W PD N + A + R+ ++G++ +
Sbjct: 104 WKDERLRFKGPMQRLPLNNLLASKIWTPDTFFHNGKKSIAHNMTTPNKLLRLEDDGTLLY 163
Query: 455 IKRLDISTPISMQLDNWXNDMQTCTFKFGS 544
RL IS MQL+++ D C KFGS
Sbjct: 164 TMRLTISAECPMQLEDFPMDAHACPLKFGS 193
>BC113422-1|AAI13423.1| 462|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 5 protein.
Length = 462
Score = 47.6 bits (108), Expect = 6e-05
Identities = 36/150 (24%), Positives = 66/150 (44%), Gaps = 7/150 (4%)
Frame = +2
Query: 116 ENATSLSLMIDSLLATYDRESPPD--SKIV-VNLTLHLRHAN-IRESESTVRILADLQMN 283
+N T + ++D LL YD P +I V +++ + ++E I + +
Sbjct: 44 DNITIFTRILDGLLDGYDNRLRPGLGERITQVRTDIYVTSFGPVSDTEMEYTIDVFFRQS 103
Query: 284 WIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSW 454
W D+RL + + + ++W PD N + A + R+ ++G++ +
Sbjct: 104 WKDERLRFKGPMQRLPLNNLLASKIWTPDTFFHNGKKSIAHNMTTPNKLLRLEDDGTLLY 163
Query: 455 IKRLDISTPISMQLDNWXNDMQTCTFKFGS 544
RL IS MQL+++ D C KFGS
Sbjct: 164 TMRLTISAECPMQLEDFPMDAHACPLKFGS 193
>BC111979-1|AAI11980.1| 462|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 5, precursor protein.
Length = 462
Score = 47.6 bits (108), Expect = 6e-05
Identities = 36/150 (24%), Positives = 66/150 (44%), Gaps = 7/150 (4%)
Frame = +2
Query: 116 ENATSLSLMIDSLLATYDRESPPD--SKIV-VNLTLHLRHAN-IRESESTVRILADLQMN 283
+N T + ++D LL YD P +I V +++ + ++E I + +
Sbjct: 44 DNITIFTRILDGLLDGYDNRLRPGLGERITQVRTDIYVTSFGPVSDTEMEYTIDVFFRQS 103
Query: 284 WIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSW 454
W D+RL + + + ++W PD N + A + R+ ++G++ +
Sbjct: 104 WKDERLRFKGPMQRLPLNNLLASKIWTPDTFFHNGKKSIAHNMTTPNKLLRLEDDGTLLY 163
Query: 455 IKRLDISTPISMQLDNWXNDMQTCTFKFGS 544
RL IS MQL+++ D C KFGS
Sbjct: 164 TMRLTISAECPMQLEDFPMDAHACPLKFGS 193
>BC110597-1|AAI10598.1| 411|Homo sapiens ligand-gated ion channel,
zinc activated 1 protein.
Length = 411
Score = 47.6 bits (108), Expect = 6e-05
Identities = 25/89 (28%), Positives = 41/89 (46%)
Frame = +2
Query: 272 LQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVS 451
L+++W+D RL+WN + E LW P + +L A D + +ARV +G V
Sbjct: 86 LRLSWLDTRLAWNTSAHPRHAITLPWESLWTPRLTILEALWVDWRDQSPQARVDQDGHVK 145
Query: 452 WIKRLDISTPISMQLDNWXNDMQTCTFKF 538
L T + +L ++ D C+ F
Sbjct: 146 LNLALTTETNCNFELLHFPRDHSNCSLSF 174
>AK122638-1|BAC85499.1| 266|Homo sapiens yte protein of 76kDa)
(LCP2). protein.
Length = 266
Score = 47.6 bits (108), Expect = 6e-05
Identities = 25/89 (28%), Positives = 41/89 (46%)
Frame = +2
Query: 272 LQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVS 451
L+++W+D RL+WN + E LW P + +L A D + +ARV +G V
Sbjct: 87 LRLSWLDTRLAWNTSAHPRHAITLPWESLWTPRLTILEALWVDWRDQSPQARVDQDGHVK 146
Query: 452 WIKRLDISTPISMQLDNWXNDMQTCTFKF 538
L T + +L ++ D C+ F
Sbjct: 147 LNLALTTETNCNFELLHFPRDHSNCSLSF 175
>AJ586911-1|CAE52911.1| 502|Homo sapiens nicotinic acetylcholine
alpha-7 subunit protein.
Length = 502
Score = 47.6 bits (108), Expect = 6e-05
Identities = 27/102 (26%), Positives = 48/102 (47%), Gaps = 2/102 (1%)
Frame = +2
Query: 272 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSNNGS 445
LQM+W D L WN E+ G T ++W+PD++L N+A + V+++G
Sbjct: 78 LQMSWTDHYLQWNVSEYPGVKTVRFPDGQIWKPDILLYNSADERFDATFHTNVLVNSSGH 137
Query: 446 VSWIKRLDISTPISMQLDNWXNDMQTCTFKFGSRMHNSDXMD 571
++ + + + + D+Q C KFGS + +D
Sbjct: 138 CQYLPPGIFKSSCYIDVRWFPFDVQHCKLKFGSWSYGGWSLD 179
>AF512521-1|AAO20969.1| 411|Homo sapiens ligand-gated ion channel
subunit protein.
Length = 411
Score = 47.6 bits (108), Expect = 6e-05
Identities = 25/89 (28%), Positives = 41/89 (46%)
Frame = +2
Query: 272 LQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVS 451
L+++W+D RL+WN + E LW P + +L A D + +ARV +G V
Sbjct: 86 LRLSWLDTRLAWNTSAHPRHAITLPWESLWTPRLTILEALWVDWRDQSPQARVDQDGHVK 145
Query: 452 WIKRLDISTPISMQLDNWXNDMQTCTFKF 538
L T + +L ++ D C+ F
Sbjct: 146 LNLALTTETNCNFELLHFPRDHSNCSLSF 174
>AB223030-1|BAE19924.1| 411|Homo sapiens ligand-gated ion-channel
receptor L2 protein.
Length = 411
Score = 47.2 bits (107), Expect = 7e-05
Identities = 25/89 (28%), Positives = 41/89 (46%)
Frame = +2
Query: 272 LQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVS 451
L+++W+D RL+WN + E LW P + +L A D + +ARV +G V
Sbjct: 86 LRLSWLDTRLAWNTSAHPRHAITLPWESLWTPRLTILEALWVDWRDQSPQARVDQDGHVK 145
Query: 452 WIKRLDISTPISMQLDNWXNDMQTCTFKF 538
L T + +L ++ D C+ F
Sbjct: 146 LNLALATETNCNFELLHFPRDHSNCSLSF 174
>AJ003080-1|CAA05853.1| 238|Homo sapiens serotonin receptor
protein.
Length = 238
Score = 46.8 bits (106), Expect = 1e-04
Identities = 26/111 (23%), Positives = 48/111 (43%), Gaps = 1/111 (0%)
Frame = +2
Query: 230 NIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAG 406
N+ E + + W D+ L WN ++ T L + ++ +W PD+++
Sbjct: 72 NVDEKNQVLTTYIWYRQYWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKS 131
Query: 407 DYALRARVSNNGSVSWIKRLDISTPISMQLDNWXNDMQTCTFKFGSRMHNS 559
+ + G V K L + T S+ + N+ D+Q C+ F S +H S
Sbjct: 132 PNIPYVYIRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLHTS 182
>U40583-1|AAA83561.1| 502|Homo sapiens alpha 7 neuronal nicotinic
acetylcholine receptor protein.
Length = 502
Score = 46.4 bits (105), Expect = 1e-04
Identities = 27/102 (26%), Positives = 47/102 (46%), Gaps = 2/102 (1%)
Frame = +2
Query: 272 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSNNGS 445
LQM+W D L WN E+ G T ++W+PD++L N+A + V+ +G
Sbjct: 78 LQMSWTDHYLQWNVSEYPGVKTVRFPDGQIWKPDILLYNSADERFDATFHTNVLVNPSGH 137
Query: 446 VSWIKRLDISTPISMQLDNWXNDMQTCTFKFGSRMHNSDXMD 571
++ + + + + D+Q C KFGS + +D
Sbjct: 138 CQYLPPGIFKSSCYIDVRWFPFDVQHCKLKFGSWSYGGWSLD 179
>BC096083-1|AAH96083.1| 198|Homo sapiens CHRNB4 protein protein.
Length = 198
Score = 46.4 bits (105), Expect = 1e-04
Identities = 30/115 (26%), Positives = 54/115 (46%), Gaps = 8/115 (6%)
Frame = +2
Query: 92 AIASAAECENATSLSLMIDSLL--ATYDRESPP--DSKIVVNLTLHLRHA---NIRESES 250
A+ C A + ++D LL Y+ P S ++++ L L A ++ E E
Sbjct: 14 ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQ 73
Query: 251 TVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDY 412
+ L+ W D RL+WN+ + G + + ++R+W PD+VL N + T +
Sbjct: 74 IMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNKSLRTGSTW 128
>BC096081-1|AAH96081.1| 198|Homo sapiens CHRNB4 protein protein.
Length = 198
Score = 46.4 bits (105), Expect = 1e-04
Identities = 30/115 (26%), Positives = 54/115 (46%), Gaps = 8/115 (6%)
Frame = +2
Query: 92 AIASAAECENATSLSLMIDSLL--ATYDRESPP--DSKIVVNLTLHLRHA---NIRESES 250
A+ C A + ++D LL Y+ P S ++++ L L A ++ E E
Sbjct: 14 ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQ 73
Query: 251 TVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDY 412
+ L+ W D RL+WN+ + G + + ++R+W PD+VL N + T +
Sbjct: 74 IMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNKSLRTGSTW 128
>BC028629-1|AAH28629.1| 492|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 3 protein.
Length = 492
Score = 46.4 bits (105), Expect = 1e-04
Identities = 34/150 (22%), Positives = 65/150 (43%), Gaps = 7/150 (4%)
Frame = +2
Query: 116 ENATSLSLMIDSLLATYDRESPP---DSKIVVNLTLHLRHAN-IRESESTVRILADLQMN 283
+N T + ++D LL YD P D+ V +++ + +++ I +
Sbjct: 62 DNITIFTRILDRLLDGYDNRLRPGLGDAVTEVKTDIYVTSFGPVSDTDMEYTIDVFFRQT 121
Query: 284 WIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSW 454
W D+RL ++ + + ++W PD N + A + R+ +NG++ +
Sbjct: 122 WHDERLKFDGPMKILPLNNLLASKIWTPDTFFHNGKKSVAHNMTTPNKLLRLVDNGTLPY 181
Query: 455 IKRLDISTPISMQLDNWXNDMQTCTFKFGS 544
RL I M L+++ D+ C KFGS
Sbjct: 182 TMRLTIHAECPMHLEDFPMDVHACPLKFGS 211
>AF385585-1|AAK68111.1| 502|Homo sapiens nicotinic cholinergic
receptor alpha 7 protein.
Length = 502
Score = 46.4 bits (105), Expect = 1e-04
Identities = 27/102 (26%), Positives = 47/102 (46%), Gaps = 2/102 (1%)
Frame = +2
Query: 272 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSNNGS 445
LQM+W D L WN E+ G T ++W+PD++L N+A + V+ +G
Sbjct: 78 LQMSWTDHYLQWNVSEYPGVKTVRFPDGQIWKPDILLYNSADERFDATFHTNVLVNPSGH 137
Query: 446 VSWIKRLDISTPISMQLDNWXNDMQTCTFKFGSRMHNSDXMD 571
++ + + + + D+Q C KFGS + +D
Sbjct: 138 CQYLPPGIFKSSCYIDVRWFPFDVQHCKLKFGSWSYGGWSLD 179
>S62908-1|AAB27279.1| 492|Homo sapiens gamma-aminobutyric acidA
receptor alpha 3 subunit protein.
Length = 492
Score = 46.0 bits (104), Expect = 2e-04
Identities = 34/150 (22%), Positives = 65/150 (43%), Gaps = 7/150 (4%)
Frame = +2
Query: 116 ENATSLSLMIDSLLATYDRESPP---DSKIVVNLTLHLRHAN-IRESESTVRILADLQMN 283
+N T + ++D LL YD P D+ V +++ + +++ I +
Sbjct: 62 DNITIFTRILDRLLDGYDNRLRPGLGDAVTEVKTDIYVTSFGPVSDTDMEYTIDVFFRQT 121
Query: 284 WIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSW 454
W D+RL ++ + + ++W PD N + A + R+ +NG++ +
Sbjct: 122 WHDERLKFDGPMKILPLNNLLASKIWTPDTFFHNGKKSVAHNMTTPNKLLRLVDNGTLLY 181
Query: 455 IKRLDISTPISMQLDNWXNDMQTCTFKFGS 544
RL I M L+++ D+ C KFGS
Sbjct: 182 TMRLTIHAECPMHLEDFPMDVHACPLKFGS 211
>M59216-1|AAA35862.1| 474|Homo sapiens gamma-aminobutyric acid
receptor beta-1 subunit protein.
Length = 474
Score = 46.0 bits (104), Expect = 2e-04
Identities = 38/168 (22%), Positives = 70/168 (41%), Gaps = 7/168 (4%)
Frame = +2
Query: 89 CAIASAAECENATSLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESESTV 256
C S E N + + +D LL YD PD + V + + + + + E
Sbjct: 23 CCAHSTNEPSNMSYVKETVDRLLKGYDIRLRPDFGGPPVDVGMRIDVASIDMVSEVNMDY 82
Query: 257 RILADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---AR 427
+ Q +W DKRLS++ + +++LW PD LN + ++ R
Sbjct: 83 TLTMYFQQSWKDKRLSYSGIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIR 142
Query: 428 VSNNGSVSWIKRLDISTPISMQLDNWXNDMQTCTFKFGSRMHNSDXMD 571
+ +G+V + R+ + M L + D Q CT + S + +D ++
Sbjct: 143 LHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIE 190
>AF166361-1|AAG12455.1| 492|Homo sapiens GABA receptor subunit
alpha 3 protein.
Length = 492
Score = 46.0 bits (104), Expect = 2e-04
Identities = 34/150 (22%), Positives = 65/150 (43%), Gaps = 7/150 (4%)
Frame = +2
Query: 116 ENATSLSLMIDSLLATYDRESPP---DSKIVVNLTLHLRHAN-IRESESTVRILADLQMN 283
+N T + ++D LL YD P D+ V +++ + +++ I +
Sbjct: 62 DNITIFTRILDRLLDGYDNRLRPGLGDAVTEVKTDIYVTSFGPVSDTDMEYTIDVFFRQT 121
Query: 284 WIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSW 454
W D+RL ++ + + ++W PD N + A + R+ +NG++ +
Sbjct: 122 WHDERLKFDGPMKILPLNNLLASKIWTPDTFFHNGKKSVAHNMTTPNKLLRLVDNGTLLY 181
Query: 455 IKRLDISTPISMQLDNWXNDMQTCTFKFGS 544
RL I M L+++ D+ C KFGS
Sbjct: 182 TMRLTIHAECPMHLEDFPMDVHACPLKFGS 211
>U77731-2|AAB38273.1| 360|Homo sapiens glycine receptor alpha 2B
subunit protein.
Length = 360
Score = 45.6 bits (103), Expect = 2e-04
Identities = 37/135 (27%), Positives = 59/135 (43%), Gaps = 8/135 (5%)
Frame = +2
Query: 164 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 331
YD P+ K VN+T ++ +I E+ R+ L+ W D RL+++
Sbjct: 58 YDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDSRLAYSEYPDDSL 117
Query: 332 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLD 499
S + +W+PD+ N D R+S NG V + RL ++ M L
Sbjct: 118 DLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLK 177
Query: 500 NWXNDMQTCTFKFGS 544
N+ D+QTCT + S
Sbjct: 178 NFPMDVQTCTMQLES 192
>S77554-1|AAB33983.1| 474|Homo sapiens GABAA receptor beta 2
subunit protein.
Length = 474
Score = 45.6 bits (103), Expect = 2e-04
Identities = 39/168 (23%), Positives = 70/168 (41%), Gaps = 7/168 (4%)
Frame = +2
Query: 89 CAIASAAECENATSLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESESTV 256
CA S + N + + +D LL YD PD + V + + + + + E
Sbjct: 23 CA-QSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDIASIDMVSEVNMDY 81
Query: 257 RILADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---AR 427
+ Q W DKRLS+N + +++LW PD LN + ++ R
Sbjct: 82 TLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIR 141
Query: 428 VSNNGSVSWIKRLDISTPISMQLDNWXNDMQTCTFKFGSRMHNSDXMD 571
+ +G+V + R+ + M L + D Q CT + S + +D ++
Sbjct: 142 LHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIE 189
>S77553-1|AAB33982.1| 512|Homo sapiens GABAA receptor beta 2
subunit protein.
Length = 512
Score = 45.6 bits (103), Expect = 2e-04
Identities = 39/168 (23%), Positives = 70/168 (41%), Gaps = 7/168 (4%)
Frame = +2
Query: 89 CAIASAAECENATSLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESESTV 256
CA S + N + + +D LL YD PD + V + + + + + E
Sbjct: 23 CA-QSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDIASIDMVSEVNMDY 81
Query: 257 RILADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---AR 427
+ Q W DKRLS+N + +++LW PD LN + ++ R
Sbjct: 82 TLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIR 141
Query: 428 VSNNGSVSWIKRLDISTPISMQLDNWXNDMQTCTFKFGSRMHNSDXMD 571
+ +G+V + R+ + M L + D Q CT + S + +D ++
Sbjct: 142 LHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIE 189
>S67368-1|AAB29370.1| 474|Homo sapiens gamma-aminobutyric acid A
receptor beta 2 subunit protein.
Length = 474
Score = 45.6 bits (103), Expect = 2e-04
Identities = 39/168 (23%), Positives = 70/168 (41%), Gaps = 7/168 (4%)
Frame = +2
Query: 89 CAIASAAECENATSLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESESTV 256
CA S + N + + +D LL YD PD + V + + + + + E
Sbjct: 23 CA-QSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDIASIDMVSEVNMDY 81
Query: 257 RILADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---AR 427
+ Q W DKRLS+N + +++LW PD LN + ++ R
Sbjct: 82 TLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIR 141
Query: 428 VSNNGSVSWIKRLDISTPISMQLDNWXNDMQTCTFKFGSRMHNSDXMD 571
+ +G+V + R+ + M L + D Q CT + S + +D ++
Sbjct: 142 LHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIE 189
>CR450343-1|CAG29339.1| 452|Homo sapiens GLRA2 protein.
Length = 452
Score = 45.6 bits (103), Expect = 2e-04
Identities = 37/135 (27%), Positives = 59/135 (43%), Gaps = 8/135 (5%)
Frame = +2
Query: 164 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 331
YD P+ K VN+T ++ +I E+ R+ L+ W D RL+++
Sbjct: 58 YDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDSRLAYSEYPDDSL 117
Query: 332 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLD 499
S + +W+PD+ N D R+S NG V + RL ++ M L
Sbjct: 118 DLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLK 177
Query: 500 NWXNDMQTCTFKFGS 544
N+ D+QTCT + S
Sbjct: 178 NFPMDVQTCTMQLES 192
>BC105639-1|AAI05640.1| 474|Homo sapiens GABRB2 protein protein.
Length = 474
Score = 45.6 bits (103), Expect = 2e-04
Identities = 39/168 (23%), Positives = 70/168 (41%), Gaps = 7/168 (4%)
Frame = +2
Query: 89 CAIASAAECENATSLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESESTV 256
CA S + N + + +D LL YD PD + V + + + + + E
Sbjct: 23 CA-QSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDIASIDMVSEVNMDY 81
Query: 257 RILADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---AR 427
+ Q W DKRLS+N + +++LW PD LN + ++ R
Sbjct: 82 TLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIR 141
Query: 428 VSNNGSVSWIKRLDISTPISMQLDNWXNDMQTCTFKFGSRMHNSDXMD 571
+ +G+V + R+ + M L + D Q CT + S + +D ++
Sbjct: 142 LHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIE 189
>BC099719-1|AAH99719.1| 474|Homo sapiens GABRB2 protein protein.
Length = 474
Score = 45.6 bits (103), Expect = 2e-04
Identities = 39/168 (23%), Positives = 70/168 (41%), Gaps = 7/168 (4%)
Frame = +2
Query: 89 CAIASAAECENATSLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESESTV 256
CA S + N + + +D LL YD PD + V + + + + + E
Sbjct: 23 CA-QSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDIASIDMVSEVNMDY 81
Query: 257 RILADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---AR 427
+ Q W DKRLS+N + +++LW PD LN + ++ R
Sbjct: 82 TLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIR 141
Query: 428 VSNNGSVSWIKRLDISTPISMQLDNWXNDMQTCTFKFGSRMHNSDXMD 571
+ +G+V + R+ + M L + D Q CT + S + +D ++
Sbjct: 142 LHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIE 189
>BC099705-1|AAH99705.1| 474|Homo sapiens GABRB2 protein protein.
Length = 474
Score = 45.6 bits (103), Expect = 2e-04
Identities = 39/168 (23%), Positives = 70/168 (41%), Gaps = 7/168 (4%)
Frame = +2
Query: 89 CAIASAAECENATSLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESESTV 256
CA S + N + + +D LL YD PD + V + + + + + E
Sbjct: 23 CA-QSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDIASIDMVSEVNMDY 81
Query: 257 RILADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---AR 427
+ Q W DKRLS+N + +++LW PD LN + ++ R
Sbjct: 82 TLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIR 141
Query: 428 VSNNGSVSWIKRLDISTPISMQLDNWXNDMQTCTFKFGSRMHNSDXMD 571
+ +G+V + R+ + M L + D Q CT + S + +D ++
Sbjct: 142 LHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIE 189
>AY437084-1|AAR87843.1| 452|Homo sapiens glycine receptor alpha2
subunit B protein.
Length = 452
Score = 45.6 bits (103), Expect = 2e-04
Identities = 37/135 (27%), Positives = 59/135 (43%), Gaps = 8/135 (5%)
Frame = +2
Query: 164 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 331
YD P+ K VN+T ++ +I E+ R+ L+ W D RL+++
Sbjct: 58 YDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDSRLAYSEYPDDSL 117
Query: 332 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLD 499
S + +W+PD+ N D R+S NG V + RL ++ M L
Sbjct: 118 DLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLK 177
Query: 500 NWXNDMQTCTFKFGS 544
N+ D+QTCT + S
Sbjct: 178 NFPMDVQTCTMQLES 192
>X52008-1|CAA36257.1| 452|Homo sapiens inhibitory glycine receptor
protein.
Length = 452
Score = 45.2 bits (102), Expect = 3e-04
Identities = 36/135 (26%), Positives = 59/135 (43%), Gaps = 8/135 (5%)
Frame = +2
Query: 164 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 331
YD P+ K VN+T ++ ++ E+ R+ L+ W D RL+++
Sbjct: 58 YDARIRPNFKGPPVNVTCNIFINSFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPDDSL 117
Query: 332 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLD 499
S + +W+PD+ N D R+S NG V + RL ++ M L
Sbjct: 118 DLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLK 177
Query: 500 NWXNDMQTCTFKFGS 544
N+ D+QTCT + S
Sbjct: 178 NFPMDVQTCTMQLES 192
>X14767-1|CAA32875.1| 474|Homo sapiens GABA-A receptor beta 1
subunit protein.
Length = 474
Score = 45.2 bits (102), Expect = 3e-04
Identities = 38/168 (22%), Positives = 69/168 (41%), Gaps = 7/168 (4%)
Frame = +2
Query: 89 CAIASAAECENATSLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESESTV 256
C S E N + +D LL YD PD + V + + + + + E
Sbjct: 23 CCAHSTNEPSNMPYVKETVDRLLKGYDIRLRPDFGGPPVDVGMRIDVASIDMVSEVNMDY 82
Query: 257 RILADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---AR 427
+ Q +W DKRLS++ + +++LW PD LN + ++ R
Sbjct: 83 TLTMYFQQSWKDKRLSYSGIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIR 142
Query: 428 VSNNGSVSWIKRLDISTPISMQLDNWXNDMQTCTFKFGSRMHNSDXMD 571
+ +G+V + R+ + M L + D Q CT + S + +D ++
Sbjct: 143 LHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIE 190
>U77731-1|AAB38272.1| 360|Homo sapiens glycine receptor alpha 2
subunit protein.
Length = 360
Score = 45.2 bits (102), Expect = 3e-04
Identities = 36/135 (26%), Positives = 59/135 (43%), Gaps = 8/135 (5%)
Frame = +2
Query: 164 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 331
YD P+ K VN+T ++ ++ E+ R+ L+ W D RL+++
Sbjct: 58 YDARIRPNFKGPPVNVTCNIFINSFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPDDSL 117
Query: 332 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLD 499
S + +W+PD+ N D R+S NG V + RL ++ M L
Sbjct: 118 DLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLK 177
Query: 500 NWXNDMQTCTFKFGS 544
N+ D+QTCT + S
Sbjct: 178 NFPMDVQTCTMQLES 192
>BC032864-1|AAH32864.1| 452|Homo sapiens glycine receptor, alpha 2
protein.
Length = 452
Score = 45.2 bits (102), Expect = 3e-04
Identities = 36/135 (26%), Positives = 59/135 (43%), Gaps = 8/135 (5%)
Frame = +2
Query: 164 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 331
YD P+ K VN+T ++ ++ E+ R+ L+ W D RL+++
Sbjct: 58 YDARIRPNFKGPPVNVTCNIFINSFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPDDSL 117
Query: 332 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLD 499
S + +W+PD+ N D R+S NG V + RL ++ M L
Sbjct: 118 DLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLK 177
Query: 500 NWXNDMQTCTFKFGS 544
N+ D+QTCT + S
Sbjct: 178 NFPMDVQTCTMQLES 192
>AY437083-1|AAR87842.1| 452|Homo sapiens glycine receptor alpha2
subunit A protein.
Length = 452
Score = 45.2 bits (102), Expect = 3e-04
Identities = 36/135 (26%), Positives = 59/135 (43%), Gaps = 8/135 (5%)
Frame = +2
Query: 164 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 331
YD P+ K VN+T ++ ++ E+ R+ L+ W D RL+++
Sbjct: 58 YDARIRPNFKGPPVNVTCNIFINSFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPDDSL 117
Query: 332 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLD 499
S + +W+PD+ N D R+S NG V + RL ++ M L
Sbjct: 118 DLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLK 177
Query: 500 NWXNDMQTCTFKFGS 544
N+ D+QTCT + S
Sbjct: 178 NFPMDVQTCTMQLES 192
>AF053495-1|AAC35290.1| 452|Homo sapiens glycine receptor alpha 2
subunit protein.
Length = 452
Score = 45.2 bits (102), Expect = 3e-04
Identities = 36/135 (26%), Positives = 59/135 (43%), Gaps = 8/135 (5%)
Frame = +2
Query: 164 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 331
YD P+ K VN+T ++ ++ E+ R+ L+ W D RL+++
Sbjct: 58 YDARIRPNFKGPPVNVTCNIFINSFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPDDSL 117
Query: 332 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLD 499
S + +W+PD+ N D R+S NG V + RL ++ M L
Sbjct: 118 DLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLK 177
Query: 500 NWXNDMQTCTFKFGS 544
N+ D+QTCT + S
Sbjct: 178 NFPMDVQTCTMQLES 192
>S81944-1|AAB36480.1| 453|Homo sapiens gamma-aminobutyric acid type
A receptor alpha 6 subunit protein.
Length = 453
Score = 44.0 bits (99), Expect = 7e-04
Identities = 34/146 (23%), Positives = 61/146 (41%), Gaps = 7/146 (4%)
Frame = +2
Query: 128 SLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESESTVRILADLQMNWIDK 295
++S ++D+LL YD P + V +++ + + E + + W D+
Sbjct: 31 NVSRILDNLLEGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTDE 90
Query: 296 RLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRA---RVSNNGSVSWIKRL 466
RL + S + ++W PD N + A + R+ NG++ + RL
Sbjct: 91 RLKFGGPTEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTMRL 150
Query: 467 DISTPISMQLDNWXNDMQTCTFKFGS 544
I+ M+L N+ D C KFGS
Sbjct: 151 TINADCPMRLVNFPMDGHACPLKFGS 176
>BC099641-1|AAH99641.1| 453|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 6 protein.
Length = 453
Score = 44.0 bits (99), Expect = 7e-04
Identities = 34/146 (23%), Positives = 61/146 (41%), Gaps = 7/146 (4%)
Frame = +2
Query: 128 SLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESESTVRILADLQMNWIDK 295
++S ++D+LL YD P + V +++ + + E + + W D+
Sbjct: 31 NVSRILDNLLEGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTDE 90
Query: 296 RLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRA---RVSNNGSVSWIKRL 466
RL + S + ++W PD N + A + R+ NG++ + RL
Sbjct: 91 RLKFGGPTEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTMRL 150
Query: 467 DISTPISMQLDNWXNDMQTCTFKFGS 544
I+ M+L N+ D C KFGS
Sbjct: 151 TINADCPMRLVNFPMDGHACPLKFGS 176
>BC099640-1|AAH99640.1| 453|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 6 protein.
Length = 453
Score = 44.0 bits (99), Expect = 7e-04
Identities = 34/146 (23%), Positives = 61/146 (41%), Gaps = 7/146 (4%)
Frame = +2
Query: 128 SLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESESTVRILADLQMNWIDK 295
++S ++D+LL YD P + V +++ + + E + + W D+
Sbjct: 31 NVSRILDNLLEGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTDE 90
Query: 296 RLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRA---RVSNNGSVSWIKRL 466
RL + S + ++W PD N + A + R+ NG++ + RL
Sbjct: 91 RLKFGGPTEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTMRL 150
Query: 467 DISTPISMQLDNWXNDMQTCTFKFGS 544
I+ M+L N+ D C KFGS
Sbjct: 151 TINADCPMRLVNFPMDGHACPLKFGS 176
>BC096242-1|AAH96242.1| 453|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 6 protein.
Length = 453
Score = 44.0 bits (99), Expect = 7e-04
Identities = 34/146 (23%), Positives = 61/146 (41%), Gaps = 7/146 (4%)
Frame = +2
Query: 128 SLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESESTVRILADLQMNWIDK 295
++S ++D+LL YD P + V +++ + + E + + W D+
Sbjct: 31 NVSRILDNLLEGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTDE 90
Query: 296 RLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRA---RVSNNGSVSWIKRL 466
RL + S + ++W PD N + A + R+ NG++ + RL
Sbjct: 91 RLKFGGPTEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTMRL 150
Query: 467 DISTPISMQLDNWXNDMQTCTFKFGS 544
I+ M+L N+ D C KFGS
Sbjct: 151 TINADCPMRLVNFPMDGHACPLKFGS 176
>BC096241-1|AAH96241.1| 453|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 6 protein.
Length = 453
Score = 44.0 bits (99), Expect = 7e-04
Identities = 34/146 (23%), Positives = 61/146 (41%), Gaps = 7/146 (4%)
Frame = +2
Query: 128 SLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESESTVRILADLQMNWIDK 295
++S ++D+LL YD P + V +++ + + E + + W D+
Sbjct: 31 NVSRILDNLLEGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTDE 90
Query: 296 RLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRA---RVSNNGSVSWIKRL 466
RL + S + ++W PD N + A + R+ NG++ + RL
Sbjct: 91 RLKFGGPTEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTMRL 150
Query: 467 DISTPISMQLDNWXNDMQTCTFKFGS 544
I+ M+L N+ D C KFGS
Sbjct: 151 TINADCPMRLVNFPMDGHACPLKFGS 176
>BC109211-1|AAI09212.1| 632|Homo sapiens gamma-aminobutyric acid
(GABA) receptor, theta protein.
Length = 632
Score = 43.6 bits (98), Expect = 0.001
Identities = 34/145 (23%), Positives = 59/145 (40%), Gaps = 7/145 (4%)
Frame = +2
Query: 113 CENATSLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESESTVRILADLQM 280
C N + ++D +L+ YD P+ + + V +++++ I E I
Sbjct: 53 CANEAVVQKILDRVLSRYDVRLRPNFGGAPVPVRISIYVTSIEQISEMNMDYTITMFFHQ 112
Query: 281 NWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSN---NGSVS 451
W D RL++ + E+LW PD LN+ D + RV +G+V
Sbjct: 113 TWKDSRLAYYETTLNLTLDYRMHEKLWVPDCYFLNSKDAFVHDVTVENRVFQLHPDGTVR 172
Query: 452 WIKRLDISTPISMQLDNWXNDMQTC 526
+ RL + S+ L + D Q C
Sbjct: 173 YGIRLTTTAACSLDLHKFPMDKQAC 197
>BC109210-1|AAI09211.1| 632|Homo sapiens gamma-aminobutyric acid
(GABA) receptor, theta protein.
Length = 632
Score = 43.6 bits (98), Expect = 0.001
Identities = 34/145 (23%), Positives = 59/145 (40%), Gaps = 7/145 (4%)
Frame = +2
Query: 113 CENATSLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESESTVRILADLQM 280
C N + ++D +L+ YD P+ + + V +++++ I E I
Sbjct: 53 CANEAVVQKILDRVLSRYDVRLRPNFGGAPVPVRISIYVTSIEQISEMNMDYTITMFFHQ 112
Query: 281 NWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSN---NGSVS 451
W D RL++ + E+LW PD LN+ D + RV +G+V
Sbjct: 113 TWKDSRLAYYETTLNLTLDYRMHEKLWVPDCYFLNSKDAFVHDVTVENRVFQLHPDGTVR 172
Query: 452 WIKRLDISTPISMQLDNWXNDMQTC 526
+ RL + S+ L + D Q C
Sbjct: 173 YGIRLTTTAACSLDLHKFPMDKQAC 197
>AF189259-1|AAF70380.1| 632|Homo sapiens GABA-A receptor theta
subunit protein.
Length = 632
Score = 43.6 bits (98), Expect = 0.001
Identities = 34/145 (23%), Positives = 59/145 (40%), Gaps = 7/145 (4%)
Frame = +2
Query: 113 CENATSLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESESTVRILADLQM 280
C N + ++D +L+ YD P+ + + V +++++ I E I
Sbjct: 53 CANEAVVQKILDRVLSRYDVRLRPNFGGAPVPVRISIYVTSIEQISEMNMDYTITMFFHQ 112
Query: 281 NWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSN---NGSVS 451
W D RL++ + E+LW PD LN+ D + RV +G+V
Sbjct: 113 TWKDSRLAYYETTLNLTLDYRMHEKLWVPDCYFLNSKDAFVHDVTVENRVFQLHPDGTVR 172
Query: 452 WIKRLDISTPISMQLDNWXNDMQTC 526
+ RL + S+ L + D Q C
Sbjct: 173 YGIRLTTTAACSLDLHKFPMDKQAC 197
>AF144648-1|AAD51172.1| 627|Homo sapiens GABA-A receptor theta
protein.
Length = 627
Score = 43.6 bits (98), Expect = 0.001
Identities = 34/145 (23%), Positives = 59/145 (40%), Gaps = 7/145 (4%)
Frame = +2
Query: 113 CENATSLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESESTVRILADLQM 280
C N + ++D +L+ YD P+ + + V +++++ I E I
Sbjct: 48 CANEAVVQKILDRVLSRYDVRLRPNFGGAPVPVRISIYVTSIEQISEMNMDYTITMFFHQ 107
Query: 281 NWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSN---NGSVS 451
W D RL++ + E+LW PD LN+ D + RV +G+V
Sbjct: 108 TWKDSRLAYYETTLNLTLDYRMHEKLWVPDCYFLNSKDAFVHDVTVENRVFQLHPDGTVR 167
Query: 452 WIKRLDISTPISMQLDNWXNDMQTC 526
+ RL + S+ L + D Q C
Sbjct: 168 YGIRLTTTAACSLDLHKFPMDKQAC 192
>U30461-1|AAB52519.1| 554|Homo sapiens GABAA receptor subunit
alpha4 protein.
Length = 554
Score = 42.3 bits (95), Expect = 0.002
Identities = 29/113 (25%), Positives = 48/113 (42%), Gaps = 3/113 (2%)
Frame = +2
Query: 239 ESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYAL 418
E E T+ + + WIDKRL ++ + ++W PD N + + +
Sbjct: 90 EMEYTMDVF--FRQTWIDKRLKYDGPIEILRLNNMMVTKVWTPDTFFRNGKKSVSHNMTA 147
Query: 419 RA---RVSNNGSVSWIKRLDISTPISMQLDNWXNDMQTCTFKFGSRMHNSDXM 568
R+ NG++ + RL IS M+L ++ D C KFGS + M
Sbjct: 148 PNKLFRIMRNGTILYTMRLTISAECPMRLVDFPMDGHACPLKFGSYAYPKSEM 200
>BC035055-1|AAH35055.1| 554|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 4 protein.
Length = 554
Score = 42.3 bits (95), Expect = 0.002
Identities = 29/113 (25%), Positives = 48/113 (42%), Gaps = 3/113 (2%)
Frame = +2
Query: 239 ESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYAL 418
E E T+ + + WIDKRL ++ + ++W PD N + + +
Sbjct: 90 EMEYTMDVF--FRQTWIDKRLKYDGPIEILRLNNMMVTKVWTPDTFFRNGKKSVSHNMTA 147
Query: 419 RA---RVSNNGSVSWIKRLDISTPISMQLDNWXNDMQTCTFKFGSRMHNSDXM 568
R+ NG++ + RL IS M+L ++ D C KFGS + M
Sbjct: 148 PNKLFRIMRNGTILYTMRLTISAECPMRLVDFPMDGHACPLKFGSYAYPKSEM 200
>BC033801-1|AAH33801.1| 452|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, delta protein.
Length = 452
Score = 42.3 bits (95), Expect = 0.002
Identities = 37/147 (25%), Positives = 61/147 (41%), Gaps = 7/147 (4%)
Frame = +2
Query: 143 IDSLLATYDRESPPD-SKIVVNLTLHLRHANI---RESESTVRILADLQMNWIDKRLSWN 310
+D L+A Y R P VN+ L L A+I E+ + L +W D RLS+N
Sbjct: 44 LDGLIAGYARNFRPGIGGPPVNVALALEVASIDHISEANMEYTMTVFLHQSWRDSRLSYN 103
Query: 311 AGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTP 481
++LW PD ++NA + D + R+ +G + + R+ +
Sbjct: 104 HTNETLGLDSRFVDKLWLPDTFIVNAKSAWFHDVTVENKLIRLQPDGVILYSIRITSTVA 163
Query: 482 ISMQLDNWXNDMQTCTFKFGSRMHNSD 562
M L + D Q C S ++S+
Sbjct: 164 CDMDLAKYPMDEQECMLDLESYGYSSE 190
>AL391845-4|CAI15436.1| 452|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, delta protein.
Length = 452
Score = 42.3 bits (95), Expect = 0.002
Identities = 37/147 (25%), Positives = 61/147 (41%), Gaps = 7/147 (4%)
Frame = +2
Query: 143 IDSLLATYDRESPPD-SKIVVNLTLHLRHANI---RESESTVRILADLQMNWIDKRLSWN 310
+D L+A Y R P VN+ L L A+I E+ + L +W D RLS+N
Sbjct: 44 LDGLIAGYARNFRPGIGGPPVNVALALEVASIDHISEANMEYTMTVFLHQSWRDSRLSYN 103
Query: 311 AGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTP 481
++LW PD ++NA + D + R+ +G + + R+ +
Sbjct: 104 HTNETLGLDSRFVDKLWLPDTFIVNAKSAWFHDVTVENKLIRLQPDGVILYSIRITSTVA 163
Query: 482 ISMQLDNWXNDMQTCTFKFGSRMHNSD 562
M L + D Q C S ++S+
Sbjct: 164 CDMDLAKYPMDEQECMLDLESYGYSSE 190
>AF016917-1|AAB70007.1| 452|Homo sapiens GABA-A receptor delta
subunit protein.
Length = 452
Score = 42.3 bits (95), Expect = 0.002
Identities = 37/147 (25%), Positives = 61/147 (41%), Gaps = 7/147 (4%)
Frame = +2
Query: 143 IDSLLATYDRESPPD-SKIVVNLTLHLRHANI---RESESTVRILADLQMNWIDKRLSWN 310
+D L+A Y R P VN+ L L A+I E+ + L +W D RLS+N
Sbjct: 44 LDGLIAGYARNFRPGIGGPPVNVALALEVASIDHISEANMEYTMTVFLHQSWRDSRLSYN 103
Query: 311 AGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTP 481
++LW PD ++NA + D + R+ +G + + R+ +
Sbjct: 104 HTNETLGLDSRFVDKLWLPDTFIVNAKSAWFHDVTVENKLIRLQPDGVILYSIRITSTVA 163
Query: 482 ISMQLDNWXNDMQTCTFKFGSRMHNSD 562
M L + D Q C S ++S+
Sbjct: 164 CDMDLAKYPMDEQECMLDLESYGYSSE 190
>BC022449-1|AAH22449.1| 474|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, beta 1 protein.
Length = 474
Score = 40.7 bits (91), Expect = 0.006
Identities = 37/168 (22%), Positives = 69/168 (41%), Gaps = 7/168 (4%)
Frame = +2
Query: 89 CAIASAAECENATSLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESESTV 256
C S E N + + +D LL YD PD + V + + + + + E
Sbjct: 23 CCAHSTNEPSNMSYVKETVDRLLKGYDIRLRPDFGGPPVDVGMRIDVASIDMVSEVNMDY 82
Query: 257 RILADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---AR 427
+ Q +W DKRLS++ + +++L PD LN + ++ R
Sbjct: 83 TLTMYFQQSWKDKRLSYSGIPLNLTLDNRVADQLCVPDTYFLNDKKSFVHGVTVKNRMIR 142
Query: 428 VSNNGSVSWIKRLDISTPISMQLDNWXNDMQTCTFKFGSRMHNSDXMD 571
+ +G+V + R+ + M L + D Q CT + S + +D ++
Sbjct: 143 LHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIE 190
>X52009-1|CAA36258.1| 449|Homo sapiens inhibitory glycine receptor
protein.
Length = 449
Score = 40.3 bits (90), Expect = 0.008
Identities = 28/109 (25%), Positives = 48/109 (44%), Gaps = 4/109 (3%)
Frame = +2
Query: 230 NIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERLWRPDVVLLNAAATTAG 406
+I E+ R+ L+ W D RL++N S + +W+PD+ N
Sbjct: 78 SIAETTMDYRVNIFLRQQWNDPRLAYNEYPDDSLDLDPSMLDSIWKPDLFFANEKGAHFH 137
Query: 407 DYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWXNDMQTCTFKFGS 544
+ R+S NG+V + R+ ++ M L N+ D+QTC + S
Sbjct: 138 EITTDNKLLRISRNGNVLYSIRITLTLACPMDLKNFPMDVQTCIMQLES 186
>BC114947-1|AAI14948.1| 457|Homo sapiens GLRA1 protein protein.
Length = 457
Score = 40.3 bits (90), Expect = 0.008
Identities = 28/109 (25%), Positives = 48/109 (44%), Gaps = 4/109 (3%)
Frame = +2
Query: 230 NIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERLWRPDVVLLNAAATTAG 406
+I E+ R+ L+ W D RL++N S + +W+PD+ N
Sbjct: 78 SIAETTMDYRVNIFLRQQWNDPRLAYNEYPDDSLDLDPSMLDSIWKPDLFFANEKGAHFH 137
Query: 407 DYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWXNDMQTCTFKFGS 544
+ R+S NG+V + R+ ++ M L N+ D+QTC + S
Sbjct: 138 EITTDNKLLRISRNGNVLYSIRITLTLACPMDLKNFPMDVQTCIMQLES 186
>BC074980-1|AAH74980.1| 449|Homo sapiens glycine receptor, alpha 1
(startle disease/hyperekplexia) protein.
Length = 449
Score = 40.3 bits (90), Expect = 0.008
Identities = 28/109 (25%), Positives = 48/109 (44%), Gaps = 4/109 (3%)
Frame = +2
Query: 230 NIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERLWRPDVVLLNAAATTAG 406
+I E+ R+ L+ W D RL++N S + +W+PD+ N
Sbjct: 78 SIAETTMDYRVNIFLRQQWNDPRLAYNEYPDDSLDLDPSMLDSIWKPDLFFANEKGAHFH 137
Query: 407 DYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWXNDMQTCTFKFGS 544
+ R+S NG+V + R+ ++ M L N+ D+QTC + S
Sbjct: 138 EITTDNKLLRISRNGNVLYSIRITLTLACPMDLKNFPMDVQTCIMQLES 186
>Z93848-1|CAI41994.1| 376|Homo sapiens glycine receptor, alpha 4
protein.
Length = 376
Score = 39.9 bits (89), Expect = 0.011
Identities = 35/135 (25%), Positives = 58/135 (42%), Gaps = 8/135 (5%)
Frame = +2
Query: 164 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 331
YD P+ K VN+T ++ ++I ++ R+ L+ W D RLS+
Sbjct: 17 YDARIRPNFKGPPVNVTCNIFINSFSSITKTTMDYRVNVFLRQQWNDPRLSYREYPDDSL 76
Query: 332 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLD 499
S + +W+PD+ N + R+ NG+V + RL + M L
Sbjct: 77 DLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLILSCLMDLK 136
Query: 500 NWXNDMQTCTFKFGS 544
N+ D+QTCT + S
Sbjct: 137 NFPMDIQTCTMQLES 151
>U95367-1|AAC51357.1| 440|Homo sapiens GABA-A receptor pi subunit
protein.
Length = 440
Score = 39.9 bits (89), Expect = 0.011
Identities = 38/154 (24%), Positives = 70/154 (45%), Gaps = 9/154 (5%)
Frame = +2
Query: 110 ECENATSLSLM-IDSLLATYDRESPPD---SKIVVNLTLHLRH-ANIRESESTVRILADL 274
E + LSL ++L A Y++ P+ + + LTL + ++I ES L
Sbjct: 29 EVGRSDKLSLPGFENLTAGYNKFLRPNFGGEPVQIALTLDIASISSISESNMDYTATIYL 88
Query: 275 QMNWIDKRLSWNAGE-WGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNG 442
+ W+D+RL + + + LV E LW PD ++ + + + + R+ +NG
Sbjct: 89 RQRWMDQRLVFEGNKSFTLDARLV--EFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNG 146
Query: 443 SVSWIKRLDISTPISMQLDNWXNDMQTCTFKFGS 544
+V + R+ + +M L + D QTC + S
Sbjct: 147 TVLYALRITTTVACNMDLSKYPMDTQTCKLQLES 180
>BC109106-1|AAI09107.1| 440|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, pi protein.
Length = 440
Score = 39.9 bits (89), Expect = 0.011
Identities = 38/154 (24%), Positives = 70/154 (45%), Gaps = 9/154 (5%)
Frame = +2
Query: 110 ECENATSLSLM-IDSLLATYDRESPPD---SKIVVNLTLHLRH-ANIRESESTVRILADL 274
E + LSL ++L A Y++ P+ + + LTL + ++I ES L
Sbjct: 29 EVGRSDKLSLPGFENLTAGYNKFLRPNFGGEPVQIALTLDIASISSISESNMDYTATIYL 88
Query: 275 QMNWIDKRLSWNAGE-WGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNG 442
+ W+D+RL + + + LV E LW PD ++ + + + + R+ +NG
Sbjct: 89 RQRWMDQRLVFEGNKSFTLDARLV--EFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNG 146
Query: 443 SVSWIKRLDISTPISMQLDNWXNDMQTCTFKFGS 544
+V + R+ + +M L + D QTC + S
Sbjct: 147 TVLYALRITTTVACNMDLSKYPMDTQTCKLQLES 180
>BC109105-1|AAI09106.1| 440|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, pi protein.
Length = 440
Score = 39.9 bits (89), Expect = 0.011
Identities = 38/154 (24%), Positives = 70/154 (45%), Gaps = 9/154 (5%)
Frame = +2
Query: 110 ECENATSLSLM-IDSLLATYDRESPPD---SKIVVNLTLHLRH-ANIRESESTVRILADL 274
E + LSL ++L A Y++ P+ + + LTL + ++I ES L
Sbjct: 29 EVGRSDKLSLPGFENLTAGYNKFLRPNFGGEPVQIALTLDIASISSISESNMDYTATIYL 88
Query: 275 QMNWIDKRLSWNAGE-WGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNG 442
+ W+D+RL + + + LV E LW PD ++ + + + + R+ +NG
Sbjct: 89 RQRWMDQRLVFEGNKSFTLDARLV--EFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNG 146
Query: 443 SVSWIKRLDISTPISMQLDNWXNDMQTCTFKFGS 544
+V + R+ + +M L + D QTC + S
Sbjct: 147 TVLYALRITTTVACNMDLSKYPMDTQTCKLQLES 180
>BC074865-1|AAH74865.1| 440|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, pi protein.
Length = 440
Score = 39.9 bits (89), Expect = 0.011
Identities = 38/154 (24%), Positives = 70/154 (45%), Gaps = 9/154 (5%)
Frame = +2
Query: 110 ECENATSLSLM-IDSLLATYDRESPPD---SKIVVNLTLHLRH-ANIRESESTVRILADL 274
E + LSL ++L A Y++ P+ + + LTL + ++I ES L
Sbjct: 29 EVGRSDKLSLPGFENLTAGYNKFLRPNFGGEPVQIALTLDIASISSISESNMDYTATIYL 88
Query: 275 QMNWIDKRLSWNAGE-WGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNG 442
+ W+D+RL + + + LV E LW PD ++ + + + + R+ +NG
Sbjct: 89 RQRWMDQRLVFEGNKSFTLDARLV--EFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNG 146
Query: 443 SVSWIKRLDISTPISMQLDNWXNDMQTCTFKFGS 544
+V + R+ + +M L + D QTC + S
Sbjct: 147 TVLYALRITTTVACNMDLSKYPMDTQTCKLQLES 180
>BC074810-1|AAH74810.1| 440|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, pi protein.
Length = 440
Score = 39.9 bits (89), Expect = 0.011
Identities = 38/154 (24%), Positives = 70/154 (45%), Gaps = 9/154 (5%)
Frame = +2
Query: 110 ECENATSLSLM-IDSLLATYDRESPPD---SKIVVNLTLHLRH-ANIRESESTVRILADL 274
E + LSL ++L A Y++ P+ + + LTL + ++I ES L
Sbjct: 29 EVGRSDKLSLPGFENLTAGYNKFLRPNFGGEPVQIALTLDIASISSISESNMDYTATIYL 88
Query: 275 QMNWIDKRLSWNAGE-WGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNG 442
+ W+D+RL + + + LV E LW PD ++ + + + + R+ +NG
Sbjct: 89 RQRWMDQRLVFEGNKSFTLDARLV--EFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNG 146
Query: 443 SVSWIKRLDISTPISMQLDNWXNDMQTCTFKFGS 544
+V + R+ + +M L + D QTC + S
Sbjct: 147 TVLYALRITTTVACNMDLSKYPMDTQTCKLQLES 180
>AL049610-1|CAI42158.1| 376|Homo sapiens glycine receptor, alpha 4
protein.
Length = 376
Score = 39.9 bits (89), Expect = 0.011
Identities = 35/135 (25%), Positives = 58/135 (42%), Gaps = 8/135 (5%)
Frame = +2
Query: 164 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 331
YD P+ K VN+T ++ ++I ++ R+ L+ W D RLS+
Sbjct: 17 YDARIRPNFKGPPVNVTCNIFINSFSSITKTTMDYRVNVFLRQQWNDPRLSYREYPDDSL 76
Query: 332 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLD 499
S + +W+PD+ N + R+ NG+V + RL + M L
Sbjct: 77 DLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLILSCLMDLK 136
Query: 500 NWXNDMQTCTFKFGS 544
N+ D+QTCT + S
Sbjct: 137 NFPMDIQTCTMQLES 151
>AF009702-1|AAC24194.1| 440|Homo sapiens GABA-A receptor pi subunit
protein.
Length = 440
Score = 39.9 bits (89), Expect = 0.011
Identities = 38/154 (24%), Positives = 70/154 (45%), Gaps = 9/154 (5%)
Frame = +2
Query: 110 ECENATSLSLM-IDSLLATYDRESPPD---SKIVVNLTLHLRH-ANIRESESTVRILADL 274
E + LSL ++L A Y++ P+ + + LTL + ++I ES L
Sbjct: 29 EVGRSDKLSLPGFENLTAGYNKFLRPNFGGEPVQIALTLDIASISSISESNMDYTATIYL 88
Query: 275 QMNWIDKRLSWNAGE-WGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNG 442
+ W+D+RL + + + LV E LW PD ++ + + + + R+ +NG
Sbjct: 89 RQRWMDQRLVFEGNKSFTLDARLV--EFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNG 146
Query: 443 SVSWIKRLDISTPISMQLDNWXNDMQTCTFKFGS 544
+V + R+ + +M L + D QTC + S
Sbjct: 147 TVLYALRITTTVACNMDLSKYPMDTQTCKLQLES 180
>U93917-1|AAC39917.1| 449|Homo sapiens glycine receptor alpha 3
subunit protein.
Length = 449
Score = 39.1 bits (87), Expect = 0.020
Identities = 34/135 (25%), Positives = 58/135 (42%), Gaps = 8/135 (5%)
Frame = +2
Query: 164 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 331
YD P+ K VN+T ++ +I E+ R+ L+ W D RL+++
Sbjct: 57 YDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPDDSL 116
Query: 332 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLD 499
S + +W+PD+ N + R+ NG+V + RL ++ M L
Sbjct: 117 DLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLK 176
Query: 500 NWXNDMQTCTFKFGS 544
N+ D+QTC + S
Sbjct: 177 NFPMDVQTCIMQLES 191
>BC036086-1|AAH36086.1| 464|Homo sapiens glycine receptor, alpha 3
protein.
Length = 464
Score = 39.1 bits (87), Expect = 0.020
Identities = 34/135 (25%), Positives = 58/135 (42%), Gaps = 8/135 (5%)
Frame = +2
Query: 164 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 331
YD P+ K VN+T ++ +I E+ R+ L+ W D RL+++
Sbjct: 57 YDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPDDSL 116
Query: 332 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLD 499
S + +W+PD+ N + R+ NG+V + RL ++ M L
Sbjct: 117 DLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLK 176
Query: 500 NWXNDMQTCTFKFGS 544
N+ D+QTC + S
Sbjct: 177 NFPMDVQTCIMQLES 191
>AF017724-1|AAC39919.1| 465|Homo sapiens glycine receptor alpha 3
subunit protein.
Length = 465
Score = 39.1 bits (87), Expect = 0.020
Identities = 34/135 (25%), Positives = 58/135 (42%), Gaps = 8/135 (5%)
Frame = +2
Query: 164 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 331
YD P+ K VN+T ++ +I E+ R+ L+ W D RL+++
Sbjct: 57 YDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPDDSL 116
Query: 332 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLD 499
S + +W+PD+ N + R+ NG+V + RL ++ M L
Sbjct: 117 DLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLK 176
Query: 500 NWXNDMQTCTFKFGS 544
N+ D+QTC + S
Sbjct: 177 NFPMDVQTCIMQLES 191
>BC114967-1|AAI14968.1| 366|Homo sapiens GLRA1 protein protein.
Length = 366
Score = 37.9 bits (84), Expect = 0.045
Identities = 26/100 (26%), Positives = 44/100 (44%), Gaps = 4/100 (4%)
Frame = +2
Query: 257 RILADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERLWRPDVVLLNAAATTAGDYALR---A 424
R+ L+ W D RL++N S + +W+PD+ N +
Sbjct: 4 RVNIFLRQQWNDPRLAYNEYPDDSLDLDPSMLDSIWKPDLFFANEKGAHFHEITTDNKLL 63
Query: 425 RVSNNGSVSWIKRLDISTPISMQLDNWXNDMQTCTFKFGS 544
R+S NG+V + R+ ++ M L N+ D+QTC + S
Sbjct: 64 RISRNGNVLYSIRITLTLACPMDLKNFPMDVQTCIMQLES 103
>AB209359-1|BAD92596.1| 533|Homo sapiens cholinergic receptor,
nicotinic, alpha polypeptide 4 precursor variant
protein.
Length = 533
Score = 33.5 bits (73), Expect = 0.97
Identities = 19/74 (25%), Positives = 32/74 (43%)
Frame = +2
Query: 356 LWRPDVVLLNAAATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWXNDMQTCTFK 535
LW +A A + +A + ++G V W + S+ + + D Q CT K
Sbjct: 25 LWLCCCTFTSADGDFAVTHLTKAHLFHDGRVQWTPPAIYKSSCSIDVTFFPFDQQNCTMK 84
Query: 536 FGSRMHNSDXMDXV 577
FGS ++ +D V
Sbjct: 85 FGSWTYDKAKIDLV 98
>BC096291-1|AAH96291.1| 556|Homo sapiens CHRNA4 protein protein.
Length = 556
Score = 32.7 bits (71), Expect = 1.7
Identities = 18/62 (29%), Positives = 31/62 (50%), Gaps = 4/62 (6%)
Frame = +2
Query: 404 GDYAL----RARVSNNGSVSWIKRLDISTPISMQLDNWXNDMQTCTFKFGSRMHNSDXMD 571
GD+A+ +A + ++G V W + S+ + + D Q CT KFGS ++ +D
Sbjct: 60 GDFAVTHLTKAHLFHDGRVQWTPPAIYKSSCSIDVTFFPFDQQNCTMKFGSWTYDKAKID 119
Query: 572 XV 577
V
Sbjct: 120 LV 121
>BC146774-1|AAI46775.1| 1114|Homo sapiens GPR124 protein protein.
Length = 1114
Score = 30.7 bits (66), Expect = 6.9
Identities = 16/55 (29%), Positives = 26/55 (47%), Gaps = 1/55 (1%)
Frame = +2
Query: 305 WNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNN-GSVSWIKRL 466
W +GEW C+ + + ++V+L T+ Y RV+NN G W + L
Sbjct: 314 WASGEWECTVSMAQGNASKKVEIVVLE----TSASYCPAERVANNRGDFRWPRTL 364
>AY181242-1|AAO27354.1| 1331|Homo sapiens G protein-coupled receptor
124 protein.
Length = 1331
Score = 30.7 bits (66), Expect = 6.9
Identities = 16/55 (29%), Positives = 26/55 (47%), Gaps = 1/55 (1%)
Frame = +2
Query: 305 WNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNN-GSVSWIKRL 466
W +GEW C+ + + ++V+L T+ Y RV+NN G W + L
Sbjct: 314 WASGEWECTVSMAQGNASKKVEIVVLE----TSASYCPAERVANNRGDFRWPRTL 364
>AK074099-1|BAB84925.1| 1310|Homo sapiens FLJ00170 protein protein.
Length = 1310
Score = 30.7 bits (66), Expect = 6.9
Identities = 16/55 (29%), Positives = 26/55 (47%), Gaps = 1/55 (1%)
Frame = +2
Query: 305 WNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNN-GSVSWIKRL 466
W +GEW C+ + + ++V+L T+ Y RV+NN G W + L
Sbjct: 293 WASGEWECTVSMAQGNASKKVEIVVLE----TSASYCPAERVANNRGDFRWPRTL 343
>AF378755-1|AAL11992.1| 1331|Homo sapiens tumor endothelial marker 5
precursor protein.
Length = 1331
Score = 30.7 bits (66), Expect = 6.9
Identities = 16/55 (29%), Positives = 26/55 (47%), Gaps = 1/55 (1%)
Frame = +2
Query: 305 WNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNN-GSVSWIKRL 466
W +GEW C+ + + ++V+L T+ Y RV+NN G W + L
Sbjct: 314 WASGEWECTVSMAQGNASKKVEIVVLE----TSASYCPAERVANNRGDFRWPRTL 364
>AB040964-1|BAA96055.2| 1206|Homo sapiens KIAA1531 protein protein.
Length = 1206
Score = 30.7 bits (66), Expect = 6.9
Identities = 16/55 (29%), Positives = 26/55 (47%), Gaps = 1/55 (1%)
Frame = +2
Query: 305 WNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNN-GSVSWIKRL 466
W +GEW C+ + + ++V+L T+ Y RV+NN G W + L
Sbjct: 406 WASGEWECTVSMAQGNASKKVEIVVLE----TSASYCPAERVANNRGDFRWPRTL 456
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 129,357,064
Number of Sequences: 237096
Number of extensions: 3132878
Number of successful extensions: 9766
Number of sequences better than 10.0: 165
Number of HSP's better than 10.0 without gapping: 7407
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 9509
length of database: 76,859,062
effective HSP length: 89
effective length of database: 55,757,518
effective search space used: 10593928420
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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