Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BmNP10_FL5_I18
(819 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
AJ306454-1|CAC34819.1| 497|Homo sapiens neuronal nicotinic acet... 75 3e-13
Y08416-1|CAA69693.1| 498|Homo sapiens nicotinic acetylcholine r... 73 1e-12
U62439-1|AAB40117.1| 498|Homo sapiens nicotinic acetylcholine r... 73 1e-12
U48861-1|AAA92123.1| 498|Homo sapiens beta 4 nicotinic acetylch... 73 1e-12
BC096082-1|AAH96082.1| 498|Homo sapiens cholinergic receptor, n... 73 1e-12
BC096080-1|AAH96080.1| 498|Homo sapiens cholinergic receptor, n... 73 1e-12
AF306329-1|AAL02062.1| 498|Homo sapiens neuronal nicotinic acet... 73 1e-12
Y08419-1|CAA69696.1| 468|Homo sapiens nicotinic acetylcholine r... 71 4e-12
U62434-1|AAB40112.1| 468|Homo sapiens nicotinic acetylcholine r... 71 4e-12
BC033639-1|AAH33639.1| 468|Homo sapiens cholinergic receptor, n... 71 4e-12
AJ306481-1|CAC34820.1| 468|Homo sapiens neuronal nicotinic acet... 71 4e-12
Y08417-1|CAA69694.1| 458|Homo sapiens nicotinic acetylcholine r... 71 5e-12
X68275-1|CAA48336.1| 451|Homo sapiens nicotinic receptor beta 4... 71 5e-12
X67513-1|CAA47851.1| 423|Homo sapiens nicotinic acetylcholine ... 71 5e-12
U62438-1|AAB40116.1| 458|Homo sapiens nicotinic acetylcholine r... 71 5e-12
BC069788-1|AAH69788.1| 458|Homo sapiens cholinergic receptor, n... 71 5e-12
BC069703-1|AAH69703.1| 458|Homo sapiens cholinergic receptor, n... 71 5e-12
BC069681-1|AAH69681.1| 458|Homo sapiens cholinergic receptor, n... 71 5e-12
AF140765-1|AAD33063.1| 458|Homo sapiens neuronal acetylcholine ... 71 5e-12
Y16281-1|CAA76154.1| 529|Homo sapiens nicotinic acetylcholine r... 70 9e-12
Y08418-1|CAA69695.1| 503|Homo sapiens nicotinic acetylcholine r... 70 9e-12
X53559-1|CAA37625.1| 474|Homo sapiens neuronal nicotinic acetyl... 70 9e-12
U62432-1|AAB40110.1| 504|Homo sapiens nicotinic acetylcholine r... 70 9e-12
U62431-1|AAB40109.1| 529|Homo sapiens nicotinic acetylcholine r... 70 9e-12
M83712-1|AAA58357.1| 468|Homo sapiens nicotinic receptor alpha ... 70 9e-12
M37981-1|AAA59942.1| 503|Homo sapiens neuronal nicotinic acetyl... 70 9e-12
BT006897-1|AAP35543.1| 505|Homo sapiens cholinergic receptor, n... 70 9e-12
BT006646-1|AAP35292.1| 489|Homo sapiens cholinergic receptor, n... 70 9e-12
BC098443-1|AAH98443.1| 504|Homo sapiens cholinergic receptor, n... 70 9e-12
BC006114-1|AAH06114.1| 489|Homo sapiens CHRNA3 protein protein. 70 9e-12
BC002996-1|AAH02996.1| 505|Homo sapiens cholinergic receptor, n... 70 9e-12
BC001642-1|AAH01642.1| 505|Homo sapiens cholinergic receptor, n... 70 9e-12
BC000513-1|AAH00513.1| 505|Homo sapiens cholinergic receptor, n... 70 9e-12
AJ007783-1|CAA07682.1| 504|Homo sapiens nicotinic acetylcholine... 70 9e-12
AF385584-1|AAK68110.1| 489|Homo sapiens nicotinic cholinergic r... 70 9e-12
M86383-1|AAC84176.1| 502|Homo sapiens nicotinic acetylcholine r... 68 5e-11
Y16282-1|CAA76155.1| 494|Homo sapiens nicotinic acetylcholine r... 66 1e-10
Y08421-1|CAA69698.1| 627|Homo sapiens nicotinic acetylcholine r... 66 1e-10
Y08415-1|CAA69692.1| 502|Homo sapiens nicotinic acetylcholine r... 66 1e-10
X89741-1|CAA61893.1| 627|Homo sapiens neuronal acetylcholine re... 66 1e-10
X87629-1|CAA60959.1| 602|Homo sapiens nicotinic acetylcholine r... 66 1e-10
X53179-1|CAA37320.1| 502|Homo sapiens precursor peptide (AA -25... 66 1e-10
U62437-1|AAB40115.1| 502|Homo sapiens nicotinic acetylcholine r... 66 1e-10
U62435-1|AAB40113.1| 494|Homo sapiens nicotinic acetylcholine r... 66 1e-10
U62433-1|AAB40111.1| 627|Homo sapiens nicotinic acetylcholine r... 66 1e-10
L35901-1|AAA64743.1| 627|Homo sapiens nicotinic acetylcholine r... 66 1e-10
DQ093071-1|AAY88737.1| 627|Homo sapiens cholinergic receptor, n... 66 1e-10
BC096290-1|AAH96290.1| 627|Homo sapiens cholinergic receptor, n... 66 1e-10
BC075041-1|AAH75041.1| 502|Homo sapiens cholinergic receptor, n... 66 1e-10
BC075040-1|AAH75040.1| 502|Homo sapiens cholinergic receptor, n... 66 1e-10
BC014456-1|AAH14456.1| 494|Homo sapiens cholinergic receptor, n... 66 1e-10
AL592078-3|CAI16184.1| 502|Homo sapiens cholinergic receptor, n... 66 1e-10
AJ001935-1|CAA05108.1| 504|Homo sapiens CHRNB2 protein. 66 1e-10
AF077186-1|AAD45422.1| 502|Homo sapiens neuronal nicotinic acet... 66 1e-10
AB079251-1|BAC06855.1| 494|Homo sapiens Nicotinic acetylcholine... 66 1e-10
X14830-1|CAA32939.1| 501|Homo sapiens protein ( Human mRNA for ... 62 2e-09
BC011371-1|AAH11371.1| 501|Homo sapiens cholinergic receptor, n... 62 2e-09
BC023553-1|AAH23553.1| 501|Homo sapiens cholinergic receptor, n... 61 4e-09
X66403-1|CAA47030.1| 493|Homo sapiens acetylcholine receptor ep... 60 9e-09
AF105999-1|AAD24503.1| 493|Homo sapiens acetylcholine receptor ... 60 9e-09
DQ644022-1|ABG35128.1| 456|Homo sapiens 5-HT3 receptor subunit ... 60 1e-08
BC131799-1|AAI31800.1| 447|Homo sapiens 5-hydroxytryptamine (se... 60 1e-08
BC101185-1|AAI01186.1| 374|Homo sapiens HTR3E protein protein. 60 1e-08
BC101183-1|AAI01184.1| 471|Homo sapiens 5-hydroxytryptamine (se... 60 1e-08
BC101182-1|AAI01183.1| 471|Homo sapiens 5-hydroxytryptamine (se... 60 1e-08
AY159813-1|AAO38167.2| 471|Homo sapiens 5-hydroxytryptamine ser... 60 1e-08
AF459285-1|AAL66182.1| 447|Homo sapiens 5-hydroxytryptamine rec... 59 2e-08
X01715-1|CAA25861.1| 520|Homo sapiens acetylcholine receptor ga... 59 2e-08
AC092165-3|AAY24103.1| 520|Homo sapiens unknown protein. 59 2e-08
Y00762-1|CAA68731.1| 457|Homo sapiens protein ( Human mRNA for ... 58 4e-08
X02502-1|CAA26344.1| 457|Homo sapiens acetylcholine receptor pr... 58 4e-08
S77094-1|AAD14247.1| 457|Homo sapiens nicotinic acetylcholine r... 58 4e-08
BC006314-1|AAH06314.1| 269|Homo sapiens CHRNA1 protein protein. 58 4e-08
AY349353-1|AAQ93477.1| 456|Homo sapiens 5-HT3c1 serotonin recep... 58 4e-08
AY349352-1|AAQ93476.1| 441|Homo sapiens 5-HT3c1 serotonin recep... 58 4e-08
AC018890-1|AAY14687.1| 457|Homo sapiens unknown protein. 58 4e-08
X55019-1|CAA38759.1| 517|Homo sapiens acetylcholine receptor de... 56 2e-07
BC093925-1|AAH93925.1| 517|Homo sapiens cholinergic receptor, n... 56 2e-07
BC093923-1|AAH93923.1| 517|Homo sapiens cholinergic receptor, n... 56 2e-07
AC092165-2|AAY24102.1| 517|Homo sapiens unknown protein. 56 2e-07
AJ295237-1|CAC16144.1| 450|Homo sapiens neuronal nicotinic acet... 54 5e-07
AJ278118-1|CAC20435.1| 450|Homo sapiens neuronal nicotinic acet... 54 5e-07
AF327367-1|AAK14333.1| 450|Homo sapiens nicotinic acetylcholine... 54 5e-07
AF199235-1|AAG00795.2| 450|Homo sapiens nicotinic acetylcholine... 54 5e-07
Z23141-1|CAA80672.1| 479|Homo sapiens cholinergic receptor, nic... 54 6e-07
Y08420-1|CAA69697.1| 502|Homo sapiens nicotinic acetylcholine r... 54 6e-07
X70297-1|CAA49778.1| 502|Homo sapiens neuronal nicotinic acetyl... 54 6e-07
U62436-1|AAB40114.1| 502|Homo sapiens nicotinic acetylcholine r... 54 6e-07
AJ586911-1|CAE52911.1| 502|Homo sapiens nicotinic acetylcholine... 54 6e-07
BC113575-1|AAI13576.1| 479|Homo sapiens cholinergic receptor, n... 54 8e-07
BC113549-1|AAI13550.1| 479|Homo sapiens cholinergic receptor, n... 54 8e-07
AY123244-1|AAM74523.1| 479|Homo sapiens nicotinic acetylcholine... 54 8e-07
AJ243342-1|CAB65091.1| 479|Homo sapiens nicotinic acetylcholine... 54 8e-07
AF227732-1|AAF61920.1| 470|Homo sapiens nicotinic acetylcholine... 54 8e-07
AC118275-1|AAY40986.1| 479|Homo sapiens unknown protein. 54 8e-07
U40583-1|AAA83561.1| 502|Homo sapiens alpha 7 neuronal nicotini... 53 1e-06
AF385585-1|AAK68111.1| 502|Homo sapiens nicotinic cholinergic r... 53 1e-06
BC110597-1|AAI10598.1| 411|Homo sapiens ligand-gated ion channe... 52 3e-06
AF512521-1|AAO20969.1| 411|Homo sapiens ligand-gated ion channe... 52 3e-06
L08485-1|AAA58490.1| 462|Homo sapiens GABA-benzodiazepine recep... 52 3e-06
BT009830-1|AAP88832.1| 462|Homo sapiens gamma-aminobutyric acid... 52 3e-06
BC113422-1|AAI13423.1| 462|Homo sapiens gamma-aminobutyric acid... 52 3e-06
BC111979-1|AAI11980.1| 462|Homo sapiens gamma-aminobutyric acid... 52 3e-06
AK122638-1|BAC85499.1| 266|Homo sapiens yte protein of 76kDa) (... 52 3e-06
AB223030-1|BAE19924.1| 411|Homo sapiens ligand-gated ion-channe... 52 3e-06
S82612-1|AAB37533.2| 478|Homo sapiens 5-hydroxytryptamine type ... 50 8e-06
D49394-1|BAA08387.1| 478|Homo sapiens serotonin 5-HT3 receptor ... 50 1e-05
BT007204-1|AAP35868.1| 484|Homo sapiens 5-hydroxytryptamine (se... 50 1e-05
BC004453-1|AAH04453.2| 478|Homo sapiens 5-hydroxytryptamine (se... 50 1e-05
BC002354-1|AAH02354.1| 478|Homo sapiens 5-hydroxytryptamine (se... 50 1e-05
AJ005205-1|CAA06442.3| 478|Homo sapiens serotonin 3 receptor pr... 50 1e-05
AJ003079-1|CAA05852.1| 478|Homo sapiens 5-hydroxytryptamine3 re... 50 1e-05
AJ003078-1|CAA05851.1| 510|Homo sapiens serotonin receptor prot... 50 1e-05
AF498984-1|AAM21131.1| 478|Homo sapiens 5-hydroxytryptamine rec... 50 1e-05
S82769-1|AAB39369.1| 467|Homo sapiens GABAA receptor gamma 3 su... 49 2e-05
BC028629-1|AAH28629.1| 492|Homo sapiens gamma-aminobutyric acid... 49 2e-05
AF269144-1|AAF99698.1| 467|Homo sapiens GABAA receptor gamma 3 ... 49 2e-05
AF228458-1|AAF63215.1| 449|Homo sapiens GABAA receptor gamma 3 ... 49 2e-05
S81944-1|AAB36480.1| 453|Homo sapiens gamma-aminobutyric acid t... 49 2e-05
S62908-1|AAB27279.1| 492|Homo sapiens gamma-aminobutyric acidA ... 49 2e-05
BC111802-1|AAI11803.1| 465|Homo sapiens CHRNG protein protein. 49 2e-05
BC099641-1|AAH99641.1| 453|Homo sapiens gamma-aminobutyric acid... 49 2e-05
BC099640-1|AAH99640.1| 453|Homo sapiens gamma-aminobutyric acid... 49 2e-05
BC096242-1|AAH96242.1| 453|Homo sapiens gamma-aminobutyric acid... 49 2e-05
BC096241-1|AAH96241.1| 453|Homo sapiens gamma-aminobutyric acid... 49 2e-05
AJ003080-1|CAA05853.1| 238|Homo sapiens serotonin receptor prot... 49 2e-05
AF166361-1|AAG12455.1| 492|Homo sapiens GABA receptor subunit a... 49 2e-05
U77731-2|AAB38273.1| 360|Homo sapiens glycine receptor alpha 2B... 48 3e-05
CR450343-1|CAG29339.1| 452|Homo sapiens GLRA2 protein. 48 3e-05
AY437084-1|AAR87843.1| 452|Homo sapiens glycine receptor alpha2... 48 3e-05
X52008-1|CAA36257.1| 452|Homo sapiens inhibitory glycine recept... 48 4e-05
U77731-1|AAB38272.1| 360|Homo sapiens glycine receptor alpha 2 ... 48 4e-05
U30461-1|AAB52519.1| 554|Homo sapiens GABAA receptor subunit al... 48 4e-05
BC035055-1|AAH35055.1| 554|Homo sapiens gamma-aminobutyric acid... 48 4e-05
BC032864-1|AAH32864.1| 452|Homo sapiens glycine receptor, alpha... 48 4e-05
AY437083-1|AAR87842.1| 452|Homo sapiens glycine receptor alpha2... 48 4e-05
AF053495-1|AAC35290.1| 452|Homo sapiens glycine receptor alpha ... 48 4e-05
M59216-1|AAA35862.1| 474|Homo sapiens gamma-aminobutyric acid r... 47 7e-05
X14767-1|CAA32875.1| 474|Homo sapiens GABA-A receptor beta 1 su... 46 1e-04
S77554-1|AAB33983.1| 474|Homo sapiens GABAA receptor beta 2 sub... 46 1e-04
S77553-1|AAB33982.1| 512|Homo sapiens GABAA receptor beta 2 sub... 46 1e-04
S67368-1|AAB29370.1| 474|Homo sapiens gamma-aminobutyric acid A... 46 1e-04
BC105639-1|AAI05640.1| 474|Homo sapiens GABRB2 protein protein. 46 1e-04
BC099719-1|AAH99719.1| 474|Homo sapiens GABRB2 protein protein. 46 1e-04
BC099705-1|AAH99705.1| 474|Homo sapiens GABRB2 protein protein. 46 1e-04
BC096083-1|AAH96083.1| 198|Homo sapiens CHRNB4 protein protein. 46 1e-04
BC096081-1|AAH96081.1| 198|Homo sapiens CHRNB4 protein protein. 46 1e-04
X52009-1|CAA36258.1| 449|Homo sapiens inhibitory glycine recept... 45 4e-04
BC114947-1|AAI14948.1| 457|Homo sapiens GLRA1 protein protein. 45 4e-04
BC074980-1|AAH74980.1| 449|Homo sapiens glycine receptor, alpha... 45 4e-04
BC109211-1|AAI09212.1| 632|Homo sapiens gamma-aminobutyric acid... 44 7e-04
BC109210-1|AAI09211.1| 632|Homo sapiens gamma-aminobutyric acid... 44 7e-04
AF189259-1|AAF70380.1| 632|Homo sapiens GABA-A receptor theta s... 44 7e-04
AF144648-1|AAD51172.1| 627|Homo sapiens GABA-A receptor theta p... 44 7e-04
BC033801-1|AAH33801.1| 452|Homo sapiens gamma-aminobutyric acid... 44 9e-04
AL391845-4|CAI15436.1| 452|Homo sapiens gamma-aminobutyric acid... 44 9e-04
AF016917-1|AAB70007.1| 452|Homo sapiens GABA-A receptor delta s... 44 9e-04
BC074795-1|AAH74795.1| 467|Homo sapiens gamma-aminobutyric acid... 43 0.001
BC069348-1|AAH69348.1| 467|Homo sapiens gamma-aminobutyric acid... 43 0.001
BC059389-1|AAH59389.1| 475|Homo sapiens gamma-aminobutyric acid... 43 0.001
AF165124-1|AAD50273.1| 467|Homo sapiens gamma-aminobutyric acid... 43 0.001
Z93848-1|CAI41994.1| 376|Homo sapiens glycine receptor, alpha 4... 43 0.002
AL049610-1|CAI42158.1| 376|Homo sapiens glycine receptor, alpha... 43 0.002
BC114967-1|AAI14968.1| 366|Homo sapiens GLRA1 protein protein. 42 0.002
X15376-1|CAA33437.1| 467|Homo sapiens GABA-A receptor gamma 2 s... 42 0.003
U93917-1|AAC39917.1| 449|Homo sapiens glycine receptor alpha 3 ... 42 0.003
BC036086-1|AAH36086.1| 464|Homo sapiens glycine receptor, alpha... 42 0.003
BC022449-1|AAH22449.1| 474|Homo sapiens gamma-aminobutyric acid... 42 0.003
AF017724-1|AAC39919.1| 465|Homo sapiens glycine receptor alpha ... 42 0.003
BC031087-1|AAH31087.1| 465|Homo sapiens gamma-aminobutyric acid... 42 0.004
U95367-1|AAC51357.1| 440|Homo sapiens GABA-A receptor pi subuni... 41 0.005
BC109106-1|AAI09107.1| 440|Homo sapiens gamma-aminobutyric acid... 41 0.005
BC109105-1|AAI09106.1| 440|Homo sapiens gamma-aminobutyric acid... 41 0.005
BC074865-1|AAH74865.1| 440|Homo sapiens gamma-aminobutyric acid... 41 0.005
BC074810-1|AAH74810.1| 440|Homo sapiens gamma-aminobutyric acid... 41 0.005
AF009702-1|AAC24194.1| 440|Homo sapiens GABA-A receptor pi subu... 41 0.005
AB209359-1|BAD92596.1| 533|Homo sapiens cholinergic receptor, n... 41 0.006
BC096291-1|AAH96291.1| 556|Homo sapiens CHRNA4 protein protein. 40 0.011
U83981-1|AAC25631.1| 674|Homo sapiens apoptosis associated prot... 31 5.0
CR457259-1|CAG33540.1| 674|Homo sapiens PPP1R15A protein. 31 5.0
BC003067-1|AAH03067.1| 674|Homo sapiens protein phosphatase 1, ... 31 5.0
AK001361-1|BAA91649.1| 674|Homo sapiens protein ( Homo sapiens ... 31 5.0
BC146774-1|AAI46775.1| 1114|Homo sapiens GPR124 protein protein. 31 6.6
AY181242-1|AAO27354.1| 1331|Homo sapiens G protein-coupled recep... 31 6.6
AK074099-1|BAB84925.1| 1310|Homo sapiens FLJ00170 protein protein. 31 6.6
AF378755-1|AAL11992.1| 1331|Homo sapiens tumor endothelial marke... 31 6.6
AB040964-1|BAA96055.2| 1206|Homo sapiens KIAA1531 protein protein. 31 6.6
AK122582-1|BAC56923.1| 1383|Homo sapiens FLJ00269 protein protein. 30 8.8
>AJ306454-1|CAC34819.1| 497|Homo sapiens neuronal nicotinic
acetylcholine receptor beta-4 subunit protein.
Length = 497
Score = 74.9 bits (176), Expect = 3e-13
Identities = 52/187 (27%), Positives = 86/187 (45%), Gaps = 11/187 (5%)
Frame = +3
Query: 81 AIASAAECENATSLSLMIDSLL--ATYD---RDSPPDSKIV-VNLTPHLRHA-NIRESES 239
A+ C A + ++D LL Y+ R + S+++ + L L ++ E E
Sbjct: 14 ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQ 73
Query: 240 TMRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRAR 416
M L+ W D RL+WN+ + G + + ++R+W PD+VL N T
Sbjct: 74 IMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNDGTYEVSVYTNLI 133
Query: 417 VSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNXDEMDXVIDKRIYSMFE 596
V +NGSV W+ + +++ +P D Q CT KF S ++ E+D V+ SM +
Sbjct: 134 VRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRSWTYDHTEIDMVLMTPTASMDD 193
Query: 597 ---SGAW 608
SG W
Sbjct: 194 FTPSGEW 200
>Y08416-1|CAA69693.1| 498|Homo sapiens nicotinic acetylcholine
receptor beta4 subunit precursor protein.
Length = 498
Score = 72.9 bits (171), Expect = 1e-12
Identities = 53/188 (28%), Positives = 87/188 (46%), Gaps = 12/188 (6%)
Frame = +3
Query: 81 AIASAAECENATSLSLMIDSLL--ATYD---RDSPPDSKIV-VNLTPHLRHA-NIRESES 239
A+ C A + ++D LL Y+ R + S+++ + L L ++ E E
Sbjct: 14 ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQ 73
Query: 240 TMRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRA 413
M L+ W D RL+WN+ + G + + ++R+W PD+VL N A T
Sbjct: 74 IMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNADGTYEVSVYTNL 133
Query: 414 RVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNXDEMDXVIDKRIYSMF 593
V +NGSV W+ + +++ +P D Q CT KF S ++ E+D V+ SM
Sbjct: 134 IVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRSWTYDHTEIDMVLMTPTASMD 193
Query: 594 E---SGAW 608
+ SG W
Sbjct: 194 DFTPSGEW 201
>U62439-1|AAB40117.1| 498|Homo sapiens nicotinic acetylcholine
receptor beta4 subunit precursor protein.
Length = 498
Score = 72.9 bits (171), Expect = 1e-12
Identities = 53/188 (28%), Positives = 87/188 (46%), Gaps = 12/188 (6%)
Frame = +3
Query: 81 AIASAAECENATSLSLMIDSLL--ATYD---RDSPPDSKIV-VNLTPHLRHA-NIRESES 239
A+ C A + ++D LL Y+ R + S+++ + L L ++ E E
Sbjct: 14 ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQ 73
Query: 240 TMRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRA 413
M L+ W D RL+WN+ + G + + ++R+W PD+VL N A T
Sbjct: 74 IMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNADGTYEVSVYTNL 133
Query: 414 RVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNXDEMDXVIDKRIYSMF 593
V +NGSV W+ + +++ +P D Q CT KF S ++ E+D V+ SM
Sbjct: 134 IVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRSWTYDHTEIDMVLMTPTASMD 193
Query: 594 E---SGAW 608
+ SG W
Sbjct: 194 DFTPSGEW 201
>U48861-1|AAA92123.1| 498|Homo sapiens beta 4 nicotinic
acetylcholine receptor subunit protein.
Length = 498
Score = 72.9 bits (171), Expect = 1e-12
Identities = 53/188 (28%), Positives = 87/188 (46%), Gaps = 12/188 (6%)
Frame = +3
Query: 81 AIASAAECENATSLSLMIDSLL--ATYD---RDSPPDSKIV-VNLTPHLRHA-NIRESES 239
A+ C A + ++D LL Y+ R + S+++ + L L ++ E E
Sbjct: 14 ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQ 73
Query: 240 TMRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRA 413
M L+ W D RL+WN+ + G + + ++R+W PD+VL N A T
Sbjct: 74 IMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNADGTYEVSVYTNL 133
Query: 414 RVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNXDEMDXVIDKRIYSMF 593
V +NGSV W+ + +++ +P D Q CT KF S ++ E+D V+ SM
Sbjct: 134 IVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRSWTYDHTEIDMVLMTPTASMD 193
Query: 594 E---SGAW 608
+ SG W
Sbjct: 194 DFTPSGEW 201
>BC096082-1|AAH96082.1| 498|Homo sapiens cholinergic receptor,
nicotinic, beta 4 protein.
Length = 498
Score = 72.9 bits (171), Expect = 1e-12
Identities = 53/188 (28%), Positives = 87/188 (46%), Gaps = 12/188 (6%)
Frame = +3
Query: 81 AIASAAECENATSLSLMIDSLL--ATYD---RDSPPDSKIV-VNLTPHLRHA-NIRESES 239
A+ C A + ++D LL Y+ R + S+++ + L L ++ E E
Sbjct: 14 ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQ 73
Query: 240 TMRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRA 413
M L+ W D RL+WN+ + G + + ++R+W PD+VL N A T
Sbjct: 74 IMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNADGTYEVSVYTNL 133
Query: 414 RVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNXDEMDXVIDKRIYSMF 593
V +NGSV W+ + +++ +P D Q CT KF S ++ E+D V+ SM
Sbjct: 134 IVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRSWTYDHTEIDMVLMTPTASMD 193
Query: 594 E---SGAW 608
+ SG W
Sbjct: 194 DFTPSGEW 201
>BC096080-1|AAH96080.1| 498|Homo sapiens cholinergic receptor,
nicotinic, beta 4 protein.
Length = 498
Score = 72.9 bits (171), Expect = 1e-12
Identities = 53/188 (28%), Positives = 87/188 (46%), Gaps = 12/188 (6%)
Frame = +3
Query: 81 AIASAAECENATSLSLMIDSLL--ATYD---RDSPPDSKIV-VNLTPHLRHA-NIRESES 239
A+ C A + ++D LL Y+ R + S+++ + L L ++ E E
Sbjct: 14 ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQ 73
Query: 240 TMRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRA 413
M L+ W D RL+WN+ + G + + ++R+W PD+VL N A T
Sbjct: 74 IMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNADGTYEVSVYTNL 133
Query: 414 RVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNXDEMDXVIDKRIYSMF 593
V +NGSV W+ + +++ +P D Q CT KF S ++ E+D V+ SM
Sbjct: 134 IVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRSWTYDHTEIDMVLMTPTASMD 193
Query: 594 E---SGAW 608
+ SG W
Sbjct: 194 DFTPSGEW 201
>AF306329-1|AAL02062.1| 498|Homo sapiens neuronal nicotinic
acetylcholine receptor beta 4 subunit protein.
Length = 498
Score = 72.9 bits (171), Expect = 1e-12
Identities = 53/188 (28%), Positives = 87/188 (46%), Gaps = 12/188 (6%)
Frame = +3
Query: 81 AIASAAECENATSLSLMIDSLL--ATYD---RDSPPDSKIV-VNLTPHLRHA-NIRESES 239
A+ C A + ++D LL Y+ R + S+++ + L L ++ E E
Sbjct: 14 ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQ 73
Query: 240 TMRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRA 413
M L+ W D RL+WN+ + G + + ++R+W PD+VL N A T
Sbjct: 74 IMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNADGTYEVSVYTNL 133
Query: 414 RVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNXDEMDXVIDKRIYSMF 593
V +NGSV W+ + +++ +P D Q CT KF S ++ E+D V+ SM
Sbjct: 134 IVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRSWTYDHTEIDMVLMTPTASMD 193
Query: 594 E---SGAW 608
+ SG W
Sbjct: 194 DFTPSGEW 201
>Y08419-1|CAA69696.1| 468|Homo sapiens nicotinic acetylcholine
receptor alpha5 subunit precursor protein.
Length = 468
Score = 71.3 bits (167), Expect = 4e-12
Identities = 37/136 (27%), Positives = 68/136 (50%), Gaps = 6/136 (4%)
Frame = +3
Query: 219 NIRESESTMRIQADLQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLLNAAATTAG 395
++ E M L+ WID +L WN ++G V S+ +W PD+VL + A
Sbjct: 85 DVDEKNQLMTTNVWLKQEWIDVKLRWNPDDYGGIKVIRVPSDSVWTPDIVLFDNADGRFE 144
Query: 396 DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNXDEMDXV--- 566
+ + + NG+V+W + + ++ + +P D+Q C+ KFGS ++ ++D +
Sbjct: 145 GTSTKTVIRYNGTVTWTPPANYKSSCTIDVTFFPFDLQNCSMKFGSWTYDGSQVDIILED 204
Query: 567 --IDKRIYSMFESGAW 608
+DKR F++G W
Sbjct: 205 QDVDKR--DFFDNGEW 218
>U62434-1|AAB40112.1| 468|Homo sapiens nicotinic acetylcholine
receptor alpha5 subunit precursor protein.
Length = 468
Score = 71.3 bits (167), Expect = 4e-12
Identities = 37/136 (27%), Positives = 68/136 (50%), Gaps = 6/136 (4%)
Frame = +3
Query: 219 NIRESESTMRIQADLQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLLNAAATTAG 395
++ E M L+ WID +L WN ++G V S+ +W PD+VL + A
Sbjct: 85 DVDEKNQLMTTNVWLKQEWIDVKLRWNPDDYGGIKVIRVPSDSVWTPDIVLFDNADGRFE 144
Query: 396 DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNXDEMDXV--- 566
+ + + NG+V+W + + ++ + +P D+Q C+ KFGS ++ ++D +
Sbjct: 145 GTSTKTVIRYNGTVTWTPPANYKSSCTIDVTFFPFDLQNCSMKFGSWTYDGSQVDIILED 204
Query: 567 --IDKRIYSMFESGAW 608
+DKR F++G W
Sbjct: 205 QDVDKR--DFFDNGEW 218
>BC033639-1|AAH33639.1| 468|Homo sapiens cholinergic receptor,
nicotinic, alpha 5 protein.
Length = 468
Score = 71.3 bits (167), Expect = 4e-12
Identities = 37/136 (27%), Positives = 68/136 (50%), Gaps = 6/136 (4%)
Frame = +3
Query: 219 NIRESESTMRIQADLQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLLNAAATTAG 395
++ E M L+ WID +L WN ++G V S+ +W PD+VL + A
Sbjct: 85 DVDEKNQLMTTNVWLKQEWIDVKLRWNPDDYGGIKVIRVPSDSVWTPDIVLFDNADGRFE 144
Query: 396 DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNXDEMDXV--- 566
+ + + NG+V+W + + ++ + +P D+Q C+ KFGS ++ ++D +
Sbjct: 145 GTSTKTVIRYNGTVTWTPPANYKSSCTIDVTFFPFDLQNCSMKFGSWTYDGSQVDIILED 204
Query: 567 --IDKRIYSMFESGAW 608
+DKR F++G W
Sbjct: 205 QDVDKR--DFFDNGEW 218
>AJ306481-1|CAC34820.1| 468|Homo sapiens neuronal nicotinic
acetylcholine receptor alpha-5subunit protein.
Length = 468
Score = 71.3 bits (167), Expect = 4e-12
Identities = 37/136 (27%), Positives = 68/136 (50%), Gaps = 6/136 (4%)
Frame = +3
Query: 219 NIRESESTMRIQADLQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLLNAAATTAG 395
++ E M L+ WID +L WN ++G V S+ +W PD+VL + A
Sbjct: 85 DVDEKNQLMTTNVWLKQEWIDVKLRWNPDDYGGIKVIRVPSDSVWTPDIVLFDNADGRFE 144
Query: 396 DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNXDEMDXV--- 566
+ + + NG+V+W + + ++ + +P D+Q C+ KFGS ++ ++D +
Sbjct: 145 GTSTKTVIRYNGTVTWTPPANYKSSCTIDVTFFPFDLQNCSMKFGSWTYDGSQVDIILED 204
Query: 567 --IDKRIYSMFESGAW 608
+DKR F++G W
Sbjct: 205 QDVDKR--DFFDNGEW 218
>Y08417-1|CAA69694.1| 458|Homo sapiens nicotinic acetylcholine
receptor beta3 subunit precursor protein.
Length = 458
Score = 70.9 bits (166), Expect = 5e-12
Identities = 40/135 (29%), Positives = 65/135 (48%), Gaps = 5/135 (3%)
Frame = +3
Query: 219 NIRESESTMRIQADLQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLL-NAAATTA 392
++ E M L+ W D +L WN ++G + V SE LW PD+VL NA
Sbjct: 67 DVDEKNQLMTTNVWLKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFE 126
Query: 393 GDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNXDEMDXV-I 569
G + V +NG+V W + +M + +P D Q C+ KFGS ++ +D + I
Sbjct: 127 GSLMTKVIVKSNGTVVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGTMVDLILI 186
Query: 570 DKRI--YSMFESGAW 608
++ + F++G W
Sbjct: 187 NENVDRKDFFDNGEW 201
>X68275-1|CAA48336.1| 451|Homo sapiens nicotinic receptor beta 4
subunit protein.
Length = 451
Score = 70.9 bits (166), Expect = 5e-12
Identities = 41/135 (30%), Positives = 66/135 (48%), Gaps = 5/135 (3%)
Frame = +3
Query: 219 NIRESESTMRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTA 392
++ E + M L+ W D RL+WN+ + G + + ++R+W PD+VL N A T
Sbjct: 20 SVNERDEIMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNADGTYE 79
Query: 393 GDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNXDEMDXVID 572
V +NGSV W+ + +++ +P D Q CT KF S ++ E+D V+
Sbjct: 80 VSVYTNLIVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRSWTYDHTEIDMVLM 139
Query: 573 KRIYSMFE---SGAW 608
SM + SG W
Sbjct: 140 TPTASMDDFTPSGEW 154
>X67513-1|CAA47851.1| 423|Homo sapiens nicotinic acetylcholine
receptor beta-3 subunit protein.
Length = 423
Score = 70.9 bits (166), Expect = 5e-12
Identities = 40/135 (29%), Positives = 65/135 (48%), Gaps = 5/135 (3%)
Frame = +3
Query: 219 NIRESESTMRIQADLQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLL-NAAATTA 392
++ E M L+ W D +L WN ++G + V SE LW PD+VL NA
Sbjct: 32 DVDEKNQLMTTNVWLKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFE 91
Query: 393 GDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNXDEMDXV-I 569
G + V +NG+V W + +M + +P D Q C+ KFGS ++ +D + I
Sbjct: 92 GSLMTKVIVKSNGTVVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGTMVDLILI 151
Query: 570 DKRI--YSMFESGAW 608
++ + F++G W
Sbjct: 152 NENVDRKDFFDNGEW 166
>U62438-1|AAB40116.1| 458|Homo sapiens nicotinic acetylcholine
receptor beta3 subunit precursor protein.
Length = 458
Score = 70.9 bits (166), Expect = 5e-12
Identities = 40/135 (29%), Positives = 65/135 (48%), Gaps = 5/135 (3%)
Frame = +3
Query: 219 NIRESESTMRIQADLQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLL-NAAATTA 392
++ E M L+ W D +L WN ++G + V SE LW PD+VL NA
Sbjct: 67 DVDEKNQLMTTNVWLKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFE 126
Query: 393 GDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNXDEMDXV-I 569
G + V +NG+V W + +M + +P D Q C+ KFGS ++ +D + I
Sbjct: 127 GSLMTKVIVKSNGTVVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGTMVDLILI 186
Query: 570 DKRI--YSMFESGAW 608
++ + F++G W
Sbjct: 187 NENVDRKDFFDNGEW 201
>BC069788-1|AAH69788.1| 458|Homo sapiens cholinergic receptor,
nicotinic, beta 3 protein.
Length = 458
Score = 70.9 bits (166), Expect = 5e-12
Identities = 40/135 (29%), Positives = 65/135 (48%), Gaps = 5/135 (3%)
Frame = +3
Query: 219 NIRESESTMRIQADLQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLL-NAAATTA 392
++ E M L+ W D +L WN ++G + V SE LW PD+VL NA
Sbjct: 67 DVDEKNQLMTTNVWLKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFE 126
Query: 393 GDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNXDEMDXV-I 569
G + V +NG+V W + +M + +P D Q C+ KFGS ++ +D + I
Sbjct: 127 GSLMTKVIVKSNGTVVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGTMVDLILI 186
Query: 570 DKRI--YSMFESGAW 608
++ + F++G W
Sbjct: 187 NENVDRKDFFDNGEW 201
>BC069703-1|AAH69703.1| 458|Homo sapiens cholinergic receptor,
nicotinic, beta 3 protein.
Length = 458
Score = 70.9 bits (166), Expect = 5e-12
Identities = 40/135 (29%), Positives = 65/135 (48%), Gaps = 5/135 (3%)
Frame = +3
Query: 219 NIRESESTMRIQADLQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLL-NAAATTA 392
++ E M L+ W D +L WN ++G + V SE LW PD+VL NA
Sbjct: 67 DVDEKNQLMTTNVWLKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFE 126
Query: 393 GDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNXDEMDXV-I 569
G + V +NG+V W + +M + +P D Q C+ KFGS ++ +D + I
Sbjct: 127 GSLMTKVIVKSNGTVVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGTMVDLILI 186
Query: 570 DKRI--YSMFESGAW 608
++ + F++G W
Sbjct: 187 NENVDRKDFFDNGEW 201
>BC069681-1|AAH69681.1| 458|Homo sapiens cholinergic receptor,
nicotinic, beta 3 protein.
Length = 458
Score = 70.9 bits (166), Expect = 5e-12
Identities = 40/135 (29%), Positives = 65/135 (48%), Gaps = 5/135 (3%)
Frame = +3
Query: 219 NIRESESTMRIQADLQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLL-NAAATTA 392
++ E M L+ W D +L WN ++G + V SE LW PD+VL NA
Sbjct: 67 DVDEKNQLMTTNVWLKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFE 126
Query: 393 GDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNXDEMDXV-I 569
G + V +NG+V W + +M + +P D Q C+ KFGS ++ +D + I
Sbjct: 127 GSLMTKVIVKSNGTVVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGTMVDLILI 186
Query: 570 DKRI--YSMFESGAW 608
++ + F++G W
Sbjct: 187 NENVDRKDFFDNGEW 201
>AF140765-1|AAD33063.1| 458|Homo sapiens neuronal acetylcholine
receptor beta-3 subunit precursor protein.
Length = 458
Score = 70.9 bits (166), Expect = 5e-12
Identities = 40/135 (29%), Positives = 65/135 (48%), Gaps = 5/135 (3%)
Frame = +3
Query: 219 NIRESESTMRIQADLQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLL-NAAATTA 392
++ E M L+ W D +L WN ++G + V SE LW PD+VL NA
Sbjct: 67 DVDEKNQLMTTNVWLKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFE 126
Query: 393 GDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNXDEMDXV-I 569
G + V +NG+V W + +M + +P D Q C+ KFGS ++ +D + I
Sbjct: 127 GSLMTKVIVKSNGTVVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGTMVDLILI 186
Query: 570 DKRI--YSMFESGAW 608
++ + F++G W
Sbjct: 187 NENVDRKDFFDNGEW 201
>Y16281-1|CAA76154.1| 529|Homo sapiens nicotinic acetylcholine
receptor alpha2 subunit precursor protein.
Length = 529
Score = 70.1 bits (164), Expect = 9e-12
Identities = 42/137 (30%), Positives = 68/137 (49%), Gaps = 7/137 (5%)
Frame = +3
Query: 219 NIRESESTMRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAA-ATTA 392
++ E M L+ W D +L WN ++G T L V SE +W PD+VL N A A
Sbjct: 97 DVDEKNQMMTTNVWLKQEWSDYKLRWNPADFGNITSLRVPSEMIWIPDIVLYNNADGEFA 156
Query: 393 GDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMH-----NXDEM 557
+ +A + + G+V W+ + S+ + +P D Q C KFGS + + ++M
Sbjct: 157 VTHMTKAHLFSTGTVHWVPPAIYKSSCSIDVTFFPFDQQNCKMKFGSWTYDKAKIDLEQM 216
Query: 558 DXVIDKRIYSMFESGAW 608
+ +D + Y +ESG W
Sbjct: 217 EQTVDLKDY--WESGEW 231
>Y08418-1|CAA69695.1| 503|Homo sapiens nicotinic acetylcholine
receptor alpha3 subunit precursor protein.
Length = 503
Score = 70.1 bits (164), Expect = 9e-12
Identities = 38/134 (28%), Positives = 66/134 (49%), Gaps = 5/134 (3%)
Frame = +3
Query: 222 IRESESTMRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAG 395
+ E M L+ W D +L WN ++G + ++ V ++++W+PD+VL N A
Sbjct: 72 VDEVNQIMETNLWLKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQV 131
Query: 396 DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNXDEMDXVI-- 569
D +A + G V+WI + + + +P D Q CT KFGS ++ ++D V+
Sbjct: 132 DDKTKALLKYTGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVLIG 191
Query: 570 -DKRIYSMFESGAW 608
+ +ESG W
Sbjct: 192 SSMNLKDYWESGEW 205
>X53559-1|CAA37625.1| 474|Homo sapiens neuronal nicotinic
acetylcholine receptor alpha-3merase protein.
Length = 474
Score = 70.1 bits (164), Expect = 9e-12
Identities = 38/134 (28%), Positives = 66/134 (49%), Gaps = 5/134 (3%)
Frame = +3
Query: 222 IRESESTMRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAG 395
+ E M L+ W D +L WN ++G + ++ V ++++W+PD+VL N A
Sbjct: 43 VDEVNQIMETNLWLKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQV 102
Query: 396 DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNXDEMDXVI-- 569
D +A + G V+WI + + + +P D Q CT KFGS ++ ++D V+
Sbjct: 103 DDKTKALLKYTGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVLIG 162
Query: 570 -DKRIYSMFESGAW 608
+ +ESG W
Sbjct: 163 SSMNLKDYWESGEW 176
>U62432-1|AAB40110.1| 504|Homo sapiens nicotinic acetylcholine
receptor alpha3 subunit precursor protein.
Length = 504
Score = 70.1 bits (164), Expect = 9e-12
Identities = 38/134 (28%), Positives = 66/134 (49%), Gaps = 5/134 (3%)
Frame = +3
Query: 222 IRESESTMRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAG 395
+ E M L+ W D +L WN ++G + ++ V ++++W+PD+VL N A
Sbjct: 73 VDEVNQIMETNLWLKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQV 132
Query: 396 DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNXDEMDXVI-- 569
D +A + G V+WI + + + +P D Q CT KFGS ++ ++D V+
Sbjct: 133 DDKTKALLKYTGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVLIG 192
Query: 570 -DKRIYSMFESGAW 608
+ +ESG W
Sbjct: 193 SSMNLKDYWESGEW 206
>U62431-1|AAB40109.1| 529|Homo sapiens nicotinic acetylcholine
receptor alpha2 subunit precursor protein.
Length = 529
Score = 70.1 bits (164), Expect = 9e-12
Identities = 42/137 (30%), Positives = 68/137 (49%), Gaps = 7/137 (5%)
Frame = +3
Query: 219 NIRESESTMRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAA-ATTA 392
++ E M L+ W D +L WN ++G T L V SE +W PD+VL N A A
Sbjct: 97 DVDEKNQMMTTNVWLKQEWSDYKLRWNPADFGNITSLRVPSEMIWIPDIVLYNNADGEFA 156
Query: 393 GDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMH-----NXDEM 557
+ +A + + G+V W+ + S+ + +P D Q C KFGS + + ++M
Sbjct: 157 VTHMTKAHLFSTGTVHWVPPAIYKSSCSIDVTFFPFDQQNCKMKFGSWTYDKAKIDLEQM 216
Query: 558 DXVIDKRIYSMFESGAW 608
+ +D + Y +ESG W
Sbjct: 217 EQTVDLKDY--WESGEW 231
>M83712-1|AAA58357.1| 468|Homo sapiens nicotinic receptor alpha 5
subunit protein.
Length = 468
Score = 70.1 bits (164), Expect = 9e-12
Identities = 37/136 (27%), Positives = 67/136 (49%), Gaps = 6/136 (4%)
Frame = +3
Query: 219 NIRESESTMRIQADLQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLLNAAATTAG 395
++ E M L+ WID +L WN ++G V S+ W PD+VL + A
Sbjct: 85 DVDEKNQLMTTNVWLKQEWIDVKLRWNPDDYGGIKVIRVPSDSSWTPDIVLFDNADGRFE 144
Query: 396 DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNXDEMDXV--- 566
+ + + NG+V+W + + ++ + +P D+Q C+ KFGS ++ ++D +
Sbjct: 145 GTSTKTVIRYNGTVTWTPPANYKSSCTIDVTFFPFDLQNCSMKFGSWTYDGSQVDIILED 204
Query: 567 --IDKRIYSMFESGAW 608
+DKR F++G W
Sbjct: 205 QDVDKR--DFFDNGEW 218
>M37981-1|AAA59942.1| 503|Homo sapiens neuronal nicotinic
acetylcholine receptor protein.
Length = 503
Score = 70.1 bits (164), Expect = 9e-12
Identities = 38/134 (28%), Positives = 66/134 (49%), Gaps = 5/134 (3%)
Frame = +3
Query: 222 IRESESTMRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAG 395
+ E M L+ W D +L WN ++G + ++ V ++++W+PD+VL N A
Sbjct: 72 VDEVNQIMETNLWLKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQV 131
Query: 396 DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNXDEMDXVI-- 569
D +A + G V+WI + + + +P D Q CT KFGS ++ ++D V+
Sbjct: 132 DDKTKALLKYTGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVLIG 191
Query: 570 -DKRIYSMFESGAW 608
+ +ESG W
Sbjct: 192 SSMNLKDYWESGEW 205
>BT006897-1|AAP35543.1| 505|Homo sapiens cholinergic receptor,
nicotinic, alpha polypeptide 3 protein.
Length = 505
Score = 70.1 bits (164), Expect = 9e-12
Identities = 38/134 (28%), Positives = 66/134 (49%), Gaps = 5/134 (3%)
Frame = +3
Query: 222 IRESESTMRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAG 395
+ E M L+ W D +L WN ++G + ++ V ++++W+PD+VL N A
Sbjct: 74 VDEVNQIMETNLWLKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQV 133
Query: 396 DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNXDEMDXVI-- 569
D +A + G V+WI + + + +P D Q CT KFGS ++ ++D V+
Sbjct: 134 DDKTKALLKYTGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVLIG 193
Query: 570 -DKRIYSMFESGAW 608
+ +ESG W
Sbjct: 194 SSMNLKDYWESGEW 207
>BT006646-1|AAP35292.1| 489|Homo sapiens cholinergic receptor,
nicotinic, alpha polypeptide 3 protein.
Length = 489
Score = 70.1 bits (164), Expect = 9e-12
Identities = 38/134 (28%), Positives = 66/134 (49%), Gaps = 5/134 (3%)
Frame = +3
Query: 222 IRESESTMRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAG 395
+ E M L+ W D +L WN ++G + ++ V ++++W+PD+VL N A
Sbjct: 74 VDEVNQIMETNLWLKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQV 133
Query: 396 DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNXDEMDXVI-- 569
D +A + G V+WI + + + +P D Q CT KFGS ++ ++D V+
Sbjct: 134 DDKTKALLKYTGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVLIG 193
Query: 570 -DKRIYSMFESGAW 608
+ +ESG W
Sbjct: 194 SSMNLKDYWESGEW 207
>BC098443-1|AAH98443.1| 504|Homo sapiens cholinergic receptor,
nicotinic, alpha 3 protein.
Length = 504
Score = 70.1 bits (164), Expect = 9e-12
Identities = 38/134 (28%), Positives = 66/134 (49%), Gaps = 5/134 (3%)
Frame = +3
Query: 222 IRESESTMRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAG 395
+ E M L+ W D +L WN ++G + ++ V ++++W+PD+VL N A
Sbjct: 73 VDEVNQIMETNLWLKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQV 132
Query: 396 DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNXDEMDXVI-- 569
D +A + G V+WI + + + +P D Q CT KFGS ++ ++D V+
Sbjct: 133 DDKTKALLKYTGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVLIG 192
Query: 570 -DKRIYSMFESGAW 608
+ +ESG W
Sbjct: 193 SSMNLKDYWESGEW 206
>BC006114-1|AAH06114.1| 489|Homo sapiens CHRNA3 protein protein.
Length = 489
Score = 70.1 bits (164), Expect = 9e-12
Identities = 38/134 (28%), Positives = 66/134 (49%), Gaps = 5/134 (3%)
Frame = +3
Query: 222 IRESESTMRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAG 395
+ E M L+ W D +L WN ++G + ++ V ++++W+PD+VL N A
Sbjct: 74 VDEVNQIMETNLWLKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQV 133
Query: 396 DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNXDEMDXVI-- 569
D +A + G V+WI + + + +P D Q CT KFGS ++ ++D V+
Sbjct: 134 DDKTKALLKYTGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVLIG 193
Query: 570 -DKRIYSMFESGAW 608
+ +ESG W
Sbjct: 194 SSMNLKDYWESGEW 207
>BC002996-1|AAH02996.1| 505|Homo sapiens cholinergic receptor,
nicotinic, alpha 3 protein.
Length = 505
Score = 70.1 bits (164), Expect = 9e-12
Identities = 38/134 (28%), Positives = 66/134 (49%), Gaps = 5/134 (3%)
Frame = +3
Query: 222 IRESESTMRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAG 395
+ E M L+ W D +L WN ++G + ++ V ++++W+PD+VL N A
Sbjct: 74 VDEVNQIMETNLWLKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQV 133
Query: 396 DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNXDEMDXVI-- 569
D +A + G V+WI + + + +P D Q CT KFGS ++ ++D V+
Sbjct: 134 DDKTKALLKYTGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVLIG 193
Query: 570 -DKRIYSMFESGAW 608
+ +ESG W
Sbjct: 194 SSMNLKDYWESGEW 207
>BC001642-1|AAH01642.1| 505|Homo sapiens cholinergic receptor,
nicotinic, alpha 3 protein.
Length = 505
Score = 70.1 bits (164), Expect = 9e-12
Identities = 38/134 (28%), Positives = 66/134 (49%), Gaps = 5/134 (3%)
Frame = +3
Query: 222 IRESESTMRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAG 395
+ E M L+ W D +L WN ++G + ++ V ++++W+PD+VL N A
Sbjct: 74 VDEVNQIMETNLWLKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQV 133
Query: 396 DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNXDEMDXVI-- 569
D +A + G V+WI + + + +P D Q CT KFGS ++ ++D V+
Sbjct: 134 DDKTKALLKYTGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVLIG 193
Query: 570 -DKRIYSMFESGAW 608
+ +ESG W
Sbjct: 194 SSMNLKDYWESGEW 207
>BC000513-1|AAH00513.1| 505|Homo sapiens cholinergic receptor,
nicotinic, alpha 3 protein.
Length = 505
Score = 70.1 bits (164), Expect = 9e-12
Identities = 38/134 (28%), Positives = 66/134 (49%), Gaps = 5/134 (3%)
Frame = +3
Query: 222 IRESESTMRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAG 395
+ E M L+ W D +L WN ++G + ++ V ++++W+PD+VL N A
Sbjct: 74 VDEVNQIMETNLWLKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQV 133
Query: 396 DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNXDEMDXVI-- 569
D +A + G V+WI + + + +P D Q CT KFGS ++ ++D V+
Sbjct: 134 DDKTKALLKYTGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVLIG 193
Query: 570 -DKRIYSMFESGAW 608
+ +ESG W
Sbjct: 194 SSMNLKDYWESGEW 207
>AJ007783-1|CAA07682.1| 504|Homo sapiens nicotinic acetylcholine
receptor alpha-3 subunit protein.
Length = 504
Score = 70.1 bits (164), Expect = 9e-12
Identities = 38/134 (28%), Positives = 66/134 (49%), Gaps = 5/134 (3%)
Frame = +3
Query: 222 IRESESTMRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAG 395
+ E M L+ W D +L WN ++G + ++ V ++++W+PD+VL N A
Sbjct: 73 VDEVNQIMETNLWLKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQV 132
Query: 396 DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNXDEMDXVI-- 569
D +A + G V+WI + + + +P D Q CT KFGS ++ ++D V+
Sbjct: 133 DDKTKALLKYTGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVLIG 192
Query: 570 -DKRIYSMFESGAW 608
+ +ESG W
Sbjct: 193 SSMNLKDYWESGEW 206
>AF385584-1|AAK68110.1| 489|Homo sapiens nicotinic cholinergic
receptor alpha 3 protein.
Length = 489
Score = 70.1 bits (164), Expect = 9e-12
Identities = 38/134 (28%), Positives = 66/134 (49%), Gaps = 5/134 (3%)
Frame = +3
Query: 222 IRESESTMRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAG 395
+ E M L+ W D +L WN ++G + ++ V ++++W+PD+VL N A
Sbjct: 68 VDEVNQIMETNLWLKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQV 127
Query: 396 DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNXDEMDXVI-- 569
D +A + G V+WI + + + +P D Q CT KFGS ++ ++D V+
Sbjct: 128 DDKTKALLKYTGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVLIG 187
Query: 570 -DKRIYSMFESGAW 608
+ +ESG W
Sbjct: 188 SSMNLKDYWESGEW 201
>M86383-1|AAC84176.1| 502|Homo sapiens nicotinic acetylcholine
receptor alpha 3 subunit precursor protein.
Length = 502
Score = 67.7 bits (158), Expect = 5e-11
Identities = 39/137 (28%), Positives = 68/137 (49%), Gaps = 8/137 (5%)
Frame = +3
Query: 222 IRESESTMRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGD 398
+ E M L+ W D +L WN +G + ++ V ++++W+PD+VL N A GD
Sbjct: 71 VDEVNQIMETNLWLKQIWNDYKLKWNPSGYGGAEFMRVPAQKIWKPDIVLYNNAV---GD 127
Query: 399 YAL----RARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNXDEMDXV 566
+ + +A + G V+WI + + + +P D Q CT KFGS ++ ++D V
Sbjct: 128 FQVTTKTKALLKYTGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLV 187
Query: 567 I---DKRIYSMFESGAW 608
+ + +ESG W
Sbjct: 188 LIGSSMNLKDYWESGEW 204
>Y16282-1|CAA76155.1| 494|Homo sapiens nicotinic acetylcholine
receptor alpha6 subunit precursor protein.
Length = 494
Score = 66.5 bits (155), Expect = 1e-10
Identities = 38/123 (30%), Positives = 63/123 (51%), Gaps = 5/123 (4%)
Frame = +3
Query: 216 ANIRESESTMRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTA 392
AN+ E M L+ W D +L W+ E+ G T V ++++W+PD+VL N A
Sbjct: 71 ANVDEVNQIMETNLWLRHIWNDYKLRWDPMEYDGIETLRVPADKIWKPDIVLYNNAV--- 127
Query: 393 GDYAL----RARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNXDEMD 560
GD+ + +A + NG ++W + M + +P D Q C+ KFGS ++ E+D
Sbjct: 128 GDFQVEGKTKALLKYNGMITWTPPAIFKSSCPMDITFFPFDHQNCSLKFGSWTYDKAEID 187
Query: 561 XVI 569
+I
Sbjct: 188 LLI 190
>Y08421-1|CAA69698.1| 627|Homo sapiens nicotinic acetylcholine
receptor alpha4 subunit precursor protein.
Length = 627
Score = 66.5 bits (155), Expect = 1e-10
Identities = 41/138 (29%), Positives = 70/138 (50%), Gaps = 8/138 (5%)
Frame = +3
Query: 219 NIRESESTMRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAG 395
++ E M ++ W D +L W+ ++ T + + SE +WRPD+VL N A G
Sbjct: 75 DVDEKNQMMTTNVWVKQEWHDYKLRWDPADYENVTSIRIPSELIWRPDIVLYNNAD---G 131
Query: 396 DYAL----RARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNXDEMDX 563
D+A+ +A + ++G V W + S+ + +P D Q CT KFGS ++ ++D
Sbjct: 132 DFAVTHLTKAHLFHDGRVQWTPPAIYKSSCSIDVTFFPFDQQNCTMKFGSWTYDKAKIDL 191
Query: 564 V-IDKRI--YSMFESGAW 608
V + R+ +ESG W
Sbjct: 192 VNMHSRVDQLDFWESGEW 209
>Y08415-1|CAA69692.1| 502|Homo sapiens nicotinic acetylcholine
receptor beta2 subunit precursor protein.
Length = 502
Score = 66.5 bits (155), Expect = 1e-10
Identities = 40/135 (29%), Positives = 64/135 (47%), Gaps = 5/135 (3%)
Frame = +3
Query: 219 NIRESESTMRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTA 392
++ E E M L W D RL+W E+ + S+ +W PDVVL N A
Sbjct: 69 SVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLPDVVLYNNADGMYE 128
Query: 393 GDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNXDEMDXVID 572
+ A VS +GS+ W+ + +++ ++P D Q CT KF S ++ E+D V+
Sbjct: 129 VSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRSWTYDRTEIDLVLK 188
Query: 573 KRIYSMFE---SGAW 608
+ S+ + SG W
Sbjct: 189 SEVASLDDFTPSGEW 203
>X89741-1|CAA61893.1| 627|Homo sapiens neuronal acetylcholine
receptor alpha-4 subunit protein.
Length = 627
Score = 66.5 bits (155), Expect = 1e-10
Identities = 41/138 (29%), Positives = 70/138 (50%), Gaps = 8/138 (5%)
Frame = +3
Query: 219 NIRESESTMRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAG 395
++ E M ++ W D +L W+ ++ T + + SE +WRPD+VL N A G
Sbjct: 75 DVDEKNQMMTTNVWVKQEWHDYKLRWDPADYENVTSIRIPSELIWRPDIVLYNNAD---G 131
Query: 396 DYAL----RARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNXDEMDX 563
D+A+ +A + ++G V W + S+ + +P D Q CT KFGS ++ ++D
Sbjct: 132 DFAVTHLTKAHLFHDGRVQWTPPAIYKSSCSIDVTFFPFDQQNCTMKFGSWTYDKAKIDL 191
Query: 564 V-IDKRI--YSMFESGAW 608
V + R+ +ESG W
Sbjct: 192 VNMHSRVDQLDFWESGEW 209
>X87629-1|CAA60959.1| 602|Homo sapiens nicotinic acetylcholine
receptor protein.
Length = 602
Score = 66.5 bits (155), Expect = 1e-10
Identities = 41/138 (29%), Positives = 70/138 (50%), Gaps = 8/138 (5%)
Frame = +3
Query: 219 NIRESESTMRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAG 395
++ E M ++ W D +L W+ ++ T + + SE +WRPD+VL N A G
Sbjct: 50 DVDEKNQMMTTNVWVKQEWHDYKLRWDPADYENVTSIRIPSELIWRPDIVLYNNAD---G 106
Query: 396 DYAL----RARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNXDEMDX 563
D+A+ +A + ++G V W + S+ + +P D Q CT KFGS ++ ++D
Sbjct: 107 DFAVTHLTKAHLFHDGRVQWTPPAIYKSSCSIDVTFFPFDQQNCTMKFGSWTYDKAKIDL 166
Query: 564 V-IDKRI--YSMFESGAW 608
V + R+ +ESG W
Sbjct: 167 VNMHSRVDQLDFWESGEW 184
>X53179-1|CAA37320.1| 502|Homo sapiens precursor peptide (AA -25 to
477) protein.
Length = 502
Score = 66.5 bits (155), Expect = 1e-10
Identities = 40/135 (29%), Positives = 64/135 (47%), Gaps = 5/135 (3%)
Frame = +3
Query: 219 NIRESESTMRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTA 392
++ E E M L W D RL+W E+ + S+ +W PDVVL N A
Sbjct: 69 SVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLPDVVLYNNADGMYE 128
Query: 393 GDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNXDEMDXVID 572
+ A VS +GS+ W+ + +++ ++P D Q CT KF S ++ E+D V+
Sbjct: 129 VSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRSWTYDRTEIDLVLK 188
Query: 573 KRIYSMFE---SGAW 608
+ S+ + SG W
Sbjct: 189 SEVASLDDFTPSGEW 203
>U62437-1|AAB40115.1| 502|Homo sapiens nicotinic acetylcholine
receptor beta2 subunit precursor protein.
Length = 502
Score = 66.5 bits (155), Expect = 1e-10
Identities = 40/135 (29%), Positives = 64/135 (47%), Gaps = 5/135 (3%)
Frame = +3
Query: 219 NIRESESTMRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTA 392
++ E E M L W D RL+W E+ + S+ +W PDVVL N A
Sbjct: 69 SVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLPDVVLYNNADGMYE 128
Query: 393 GDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNXDEMDXVID 572
+ A VS +GS+ W+ + +++ ++P D Q CT KF S ++ E+D V+
Sbjct: 129 VSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRSWTYDRTEIDLVLK 188
Query: 573 KRIYSMFE---SGAW 608
+ S+ + SG W
Sbjct: 189 SEVASLDDFTPSGEW 203
>U62435-1|AAB40113.1| 494|Homo sapiens nicotinic acetylcholine
receptor alpha6 subunit precursor protein.
Length = 494
Score = 66.5 bits (155), Expect = 1e-10
Identities = 38/123 (30%), Positives = 63/123 (51%), Gaps = 5/123 (4%)
Frame = +3
Query: 216 ANIRESESTMRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTA 392
AN+ E M L+ W D +L W+ E+ G T V ++++W+PD+VL N A
Sbjct: 71 ANVDEVNQIMETNLWLRHIWNDYKLRWDPMEYDGIETLRVPADKIWKPDIVLYNNAV--- 127
Query: 393 GDYAL----RARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNXDEMD 560
GD+ + +A + NG ++W + M + +P D Q C+ KFGS ++ E+D
Sbjct: 128 GDFQVEGKTKALLKYNGMITWTPPAIFKSSCPMDITFFPFDHQNCSLKFGSWTYDKAEID 187
Query: 561 XVI 569
+I
Sbjct: 188 LLI 190
>U62433-1|AAB40111.1| 627|Homo sapiens nicotinic acetylcholine
receptor alpha4 subunit precursor protein.
Length = 627
Score = 66.5 bits (155), Expect = 1e-10
Identities = 41/138 (29%), Positives = 70/138 (50%), Gaps = 8/138 (5%)
Frame = +3
Query: 219 NIRESESTMRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAG 395
++ E M ++ W D +L W+ ++ T + + SE +WRPD+VL N A G
Sbjct: 75 DVDEKNQMMTTNVWVKQEWHDYKLRWDPADYENVTSIRIPSELIWRPDIVLYNNAD---G 131
Query: 396 DYAL----RARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNXDEMDX 563
D+A+ +A + ++G V W + S+ + +P D Q CT KFGS ++ ++D
Sbjct: 132 DFAVTHLTKAHLFHDGRVQWTPPAIYKSSCSIDVTFFPFDQQNCTMKFGSWTYDKAKIDL 191
Query: 564 V-IDKRI--YSMFESGAW 608
V + R+ +ESG W
Sbjct: 192 VNMHSRVDQLDFWESGEW 209
>L35901-1|AAA64743.1| 627|Homo sapiens nicotinic acetylcholine
receptor alpha 4 subunit protein.
Length = 627
Score = 66.5 bits (155), Expect = 1e-10
Identities = 41/138 (29%), Positives = 70/138 (50%), Gaps = 8/138 (5%)
Frame = +3
Query: 219 NIRESESTMRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAG 395
++ E M ++ W D +L W+ ++ T + + SE +WRPD+VL N A G
Sbjct: 75 DVDEKNQMMTTNVWVKQEWHDYKLRWDPADYENVTSIRIPSELIWRPDIVLYNNAD---G 131
Query: 396 DYAL----RARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNXDEMDX 563
D+A+ +A + ++G V W + S+ + +P D Q CT KFGS ++ ++D
Sbjct: 132 DFAVTHLTKAHLFHDGRVQWTPPAIYKSSCSIDVTFFPFDQQNCTMKFGSWTYDKAKIDL 191
Query: 564 V-IDKRI--YSMFESGAW 608
V + R+ +ESG W
Sbjct: 192 VNMHSRVDQLDFWESGEW 209
>DQ093071-1|AAY88737.1| 627|Homo sapiens cholinergic receptor,
nicotinic, alpha polypeptide 4 protein.
Length = 627
Score = 66.5 bits (155), Expect = 1e-10
Identities = 41/138 (29%), Positives = 70/138 (50%), Gaps = 8/138 (5%)
Frame = +3
Query: 219 NIRESESTMRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAG 395
++ E M ++ W D +L W+ ++ T + + SE +WRPD+VL N A G
Sbjct: 75 DVDEKNQMMTTNVWVKQEWHDYKLRWDPADYENVTSIRIPSELIWRPDIVLYNNAD---G 131
Query: 396 DYAL----RARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNXDEMDX 563
D+A+ +A + ++G V W + S+ + +P D Q CT KFGS ++ ++D
Sbjct: 132 DFAVTHLTKAHLFHDGRVQWTPPAIYKSSCSIDVTFFPFDQQNCTMKFGSWTYDKAKIDL 191
Query: 564 V-IDKRI--YSMFESGAW 608
V + R+ +ESG W
Sbjct: 192 VNMHSRVDQLDFWESGEW 209
>BC096290-1|AAH96290.1| 627|Homo sapiens cholinergic receptor,
nicotinic, alpha 4 protein.
Length = 627
Score = 66.5 bits (155), Expect = 1e-10
Identities = 41/138 (29%), Positives = 70/138 (50%), Gaps = 8/138 (5%)
Frame = +3
Query: 219 NIRESESTMRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAG 395
++ E M ++ W D +L W+ ++ T + + SE +WRPD+VL N A G
Sbjct: 75 DVDEKNQMMTTNVWVKQEWHDYKLRWDPADYENVTSIRIPSELIWRPDIVLYNNAD---G 131
Query: 396 DYAL----RARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNXDEMDX 563
D+A+ +A + ++G V W + S+ + +P D Q CT KFGS ++ ++D
Sbjct: 132 DFAVTHLTKAHLFHDGRVQWTPPAIYKSSCSIDVTFFPFDQQNCTMKFGSWTYDKAKIDL 191
Query: 564 V-IDKRI--YSMFESGAW 608
V + R+ +ESG W
Sbjct: 192 VNMHSRVDQLDFWESGEW 209
>BC075041-1|AAH75041.1| 502|Homo sapiens cholinergic receptor,
nicotinic, beta 2 (neuronal) protein.
Length = 502
Score = 66.5 bits (155), Expect = 1e-10
Identities = 40/135 (29%), Positives = 64/135 (47%), Gaps = 5/135 (3%)
Frame = +3
Query: 219 NIRESESTMRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTA 392
++ E E M L W D RL+W E+ + S+ +W PDVVL N A
Sbjct: 69 SVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLPDVVLYNNADGMYE 128
Query: 393 GDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNXDEMDXVID 572
+ A VS +GS+ W+ + +++ ++P D Q CT KF S ++ E+D V+
Sbjct: 129 VSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRSWTYDRTEIDLVLK 188
Query: 573 KRIYSMFE---SGAW 608
+ S+ + SG W
Sbjct: 189 SEVASLDDFTPSGEW 203
>BC075040-1|AAH75040.1| 502|Homo sapiens cholinergic receptor,
nicotinic, beta 2 (neuronal) protein.
Length = 502
Score = 66.5 bits (155), Expect = 1e-10
Identities = 40/135 (29%), Positives = 64/135 (47%), Gaps = 5/135 (3%)
Frame = +3
Query: 219 NIRESESTMRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTA 392
++ E E M L W D RL+W E+ + S+ +W PDVVL N A
Sbjct: 69 SVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLPDVVLYNNADGMYE 128
Query: 393 GDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNXDEMDXVID 572
+ A VS +GS+ W+ + +++ ++P D Q CT KF S ++ E+D V+
Sbjct: 129 VSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRSWTYDRTEIDLVLK 188
Query: 573 KRIYSMFE---SGAW 608
+ S+ + SG W
Sbjct: 189 SEVASLDDFTPSGEW 203
>BC014456-1|AAH14456.1| 494|Homo sapiens cholinergic receptor,
nicotinic, alpha 6 protein.
Length = 494
Score = 66.5 bits (155), Expect = 1e-10
Identities = 38/123 (30%), Positives = 63/123 (51%), Gaps = 5/123 (4%)
Frame = +3
Query: 216 ANIRESESTMRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTA 392
AN+ E M L+ W D +L W+ E+ G T V ++++W+PD+VL N A
Sbjct: 71 ANVDEVNQIMETNLWLRHIWNDYKLRWDPMEYDGIETLRVPADKIWKPDIVLYNNAV--- 127
Query: 393 GDYAL----RARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNXDEMD 560
GD+ + +A + NG ++W + M + +P D Q C+ KFGS ++ E+D
Sbjct: 128 GDFQVEGKTKALLKYNGMITWTPPAIFKSSCPMDITFFPFDHQNCSLKFGSWTYDKAEID 187
Query: 561 XVI 569
+I
Sbjct: 188 LLI 190
>AL592078-3|CAI16184.1| 502|Homo sapiens cholinergic receptor,
nicotinic, beta 2 (neuronal) protein.
Length = 502
Score = 66.5 bits (155), Expect = 1e-10
Identities = 40/135 (29%), Positives = 64/135 (47%), Gaps = 5/135 (3%)
Frame = +3
Query: 219 NIRESESTMRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTA 392
++ E E M L W D RL+W E+ + S+ +W PDVVL N A
Sbjct: 69 SVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLPDVVLYNNADGMYE 128
Query: 393 GDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNXDEMDXVID 572
+ A VS +GS+ W+ + +++ ++P D Q CT KF S ++ E+D V+
Sbjct: 129 VSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRSWTYDRTEIDLVLK 188
Query: 573 KRIYSMFE---SGAW 608
+ S+ + SG W
Sbjct: 189 SEVASLDDFTPSGEW 203
>AJ001935-1|CAA05108.1| 504|Homo sapiens CHRNB2 protein.
Length = 504
Score = 66.5 bits (155), Expect = 1e-10
Identities = 40/135 (29%), Positives = 64/135 (47%), Gaps = 5/135 (3%)
Frame = +3
Query: 219 NIRESESTMRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTA 392
++ E E M L W D RL+W E+ + S+ +W PDVVL N A
Sbjct: 69 SVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLPDVVLYNNADGMYE 128
Query: 393 GDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNXDEMDXVID 572
+ A VS +GS+ W+ + +++ ++P D Q CT KF S ++ E+D V+
Sbjct: 129 VSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRSWTYDRTEIDLVLK 188
Query: 573 KRIYSMFE---SGAW 608
+ S+ + SG W
Sbjct: 189 SEVASLDDFTPSGEW 203
>AF077186-1|AAD45422.1| 502|Homo sapiens neuronal nicotinic
acetylcholine receptor beta 2 protein.
Length = 502
Score = 66.5 bits (155), Expect = 1e-10
Identities = 40/135 (29%), Positives = 64/135 (47%), Gaps = 5/135 (3%)
Frame = +3
Query: 219 NIRESESTMRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTA 392
++ E E M L W D RL+W E+ + S+ +W PDVVL N A
Sbjct: 69 SVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLPDVVLYNNADGMYE 128
Query: 393 GDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNXDEMDXVID 572
+ A VS +GS+ W+ + +++ ++P D Q CT KF S ++ E+D V+
Sbjct: 129 VSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRSWTYDRTEIDLVLK 188
Query: 573 KRIYSMFE---SGAW 608
+ S+ + SG W
Sbjct: 189 SEVASLDDFTPSGEW 203
>AB079251-1|BAC06855.1| 494|Homo sapiens Nicotinic acetylcholine
receptor alpha 6 protein.
Length = 494
Score = 66.5 bits (155), Expect = 1e-10
Identities = 38/123 (30%), Positives = 63/123 (51%), Gaps = 5/123 (4%)
Frame = +3
Query: 216 ANIRESESTMRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTA 392
AN+ E M L+ W D +L W+ E+ G T V ++++W+PD+VL N A
Sbjct: 71 ANVDEVNQIMETNLWLRHIWNDYKLRWDPMEYDGIETLRVPADKIWKPDIVLYNNAV--- 127
Query: 393 GDYAL----RARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNXDEMD 560
GD+ + +A + NG ++W + M + +P D Q C+ KFGS ++ E+D
Sbjct: 128 GDFQVEGKTKALLKYNGMITWTPPAIFKSSCPMDITFFPFDHQNCSLKFGSWTYDKAEID 187
Query: 561 XVI 569
+I
Sbjct: 188 LLI 190
>X14830-1|CAA32939.1| 501|Homo sapiens protein ( Human mRNA for
muscle acetylcholine receptor beta-subunit. ).
Length = 501
Score = 62.5 bits (145), Expect = 2e-09
Identities = 39/116 (33%), Positives = 59/116 (50%), Gaps = 3/116 (2%)
Frame = +3
Query: 219 NIRESESTMRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAG 395
++ E + M + L + W D RLSW+ E G + +++E +W PDVVLLN
Sbjct: 65 SLNEKDEEMSTKVYLDLEWTDYRLSWDPAEHDGIDSLRITAESVWLPDVVLLNNNDGNF- 123
Query: 396 DYAL--RARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNXDEM 557
D AL VS++GSV W + S+Q+ +P D Q CT F S ++ E+
Sbjct: 124 DVALDISVVVSSDGSVRWQPPGIYRSSCSIQVTYFPFDWQNCTMVFSSYSYDSSEV 179
>BC011371-1|AAH11371.1| 501|Homo sapiens cholinergic receptor,
nicotinic, beta 1 (muscle) protein.
Length = 501
Score = 62.5 bits (145), Expect = 2e-09
Identities = 39/116 (33%), Positives = 59/116 (50%), Gaps = 3/116 (2%)
Frame = +3
Query: 219 NIRESESTMRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAG 395
++ E + M + L + W D RLSW+ E G + +++E +W PDVVLLN
Sbjct: 65 SLNEKDEEMSTKVYLDLEWTDYRLSWDPAEHDGIDSLRITAESVWLPDVVLLNNNDGNF- 123
Query: 396 DYAL--RARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNXDEM 557
D AL VS++GSV W + S+Q+ +P D Q CT F S ++ E+
Sbjct: 124 DVALDISVVVSSDGSVRWQPPGIYRSSCSIQVTYFPFDWQNCTMVFSSYSYDSSEV 179
>BC023553-1|AAH23553.1| 501|Homo sapiens cholinergic receptor,
nicotinic, beta 1 (muscle) protein.
Length = 501
Score = 61.3 bits (142), Expect = 4e-09
Identities = 37/118 (31%), Positives = 60/118 (50%), Gaps = 5/118 (4%)
Frame = +3
Query: 219 NIRESESTMRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAG 395
++ E + M + L + W D RLSW+ E G + +++E +W PDVVLLN G
Sbjct: 65 SLNEKDEEMSTKVYLDLEWTDYRLSWDPAEHDGIDSLRITAESVWLPDVVLLN---NNDG 121
Query: 396 DY----ALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNXDEM 557
++ + VS++GSV W + S+Q+ +P D Q CT F S ++ E+
Sbjct: 122 NFYVALDISVVVSSDGSVRWQPPGIYRSSCSIQVTYFPFDWQNCTMVFSSYSYDSSEV 179
>X66403-1|CAA47030.1| 493|Homo sapiens acetylcholine receptor
epsilon subunit CHRNE protein.
Length = 493
Score = 60.1 bits (139), Expect = 9e-09
Identities = 35/133 (26%), Positives = 68/133 (51%), Gaps = 3/133 (2%)
Frame = +3
Query: 171 PDSKIVVNLTPHLRHA-NIRESESTMRIQADLQMNWIDKRLSWNAGEWG-CSTWLVSSER 344
P+ + ++L L + ++ E E T+ + ++W D RL+++ ++G T V SE
Sbjct: 45 PEDTVTISLKVTLTNLISLNEKEETLTTSVWIGIDWQDYRLNYSKDDFGGIETLRVPSEL 104
Query: 345 LWRPDVVLLNAAATTAG-DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTF 521
+W P++VL N G Y V GSV+W+ + ++++ +P D Q C+
Sbjct: 105 VWLPEIVLENNIDGQFGVAYDANVLVYEGGSVTWLPPAIYRSVCAVEVTYFPFDWQNCSL 164
Query: 522 KFGSRMHNXDEMD 560
F S+ +N +E++
Sbjct: 165 IFRSQTYNAEEVE 177
>AF105999-1|AAD24503.1| 493|Homo sapiens acetylcholine receptor
epsilon subunit protein.
Length = 493
Score = 60.1 bits (139), Expect = 9e-09
Identities = 35/133 (26%), Positives = 68/133 (51%), Gaps = 3/133 (2%)
Frame = +3
Query: 171 PDSKIVVNLTPHLRHA-NIRESESTMRIQADLQMNWIDKRLSWNAGEWG-CSTWLVSSER 344
P+ + ++L L + ++ E E T+ + ++W D RL+++ ++G T V SE
Sbjct: 45 PEDTVTISLKVTLTNLISLNEKEETLTTSVWIGIDWQDYRLNYSKDDFGGIETLRVPSEL 104
Query: 345 LWRPDVVLLNAAATTAG-DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTF 521
+W P++VL N G Y V GSV+W+ + ++++ +P D Q C+
Sbjct: 105 VWLPEIVLENNIDGQFGVAYDANVLVYEGGSVTWLPPAIYRSVCAVEVTYFPFDWQNCSL 164
Query: 522 KFGSRMHNXDEMD 560
F S+ +N +E++
Sbjct: 165 IFRSQTYNAEEVE 177
>DQ644022-1|ABG35128.1| 456|Homo sapiens 5-HT3 receptor subunit E
splice variant HTR3Ea protein.
Length = 456
Score = 59.7 bits (138), Expect = 1e-08
Identities = 29/114 (25%), Positives = 58/114 (50%), Gaps = 1/114 (0%)
Frame = +3
Query: 261 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 437
L+M W + +SWN E G + ++++ LW PD+ ++ L A VSN G +
Sbjct: 91 LEMVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEGRI 150
Query: 438 SWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNXDEMDXVIDKRIYSMFES 599
+ K + + + ++ + +P D Q CT F S ++ D M ++K ++ + ++
Sbjct: 151 RYKKPMKVDSICNLDIFYFPFDQQNCTLTFSSFLYTVDSMLLDMEKEVWEITDA 204
>BC131799-1|AAI31800.1| 447|Homo sapiens 5-hydroxytryptamine
(serotonin) receptor 3, family member C protein.
Length = 447
Score = 59.7 bits (138), Expect = 1e-08
Identities = 28/114 (24%), Positives = 59/114 (51%), Gaps = 1/114 (0%)
Frame = +3
Query: 261 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 437
+ + W + ++WN E G + V +E LW PD+ ++ + L A +S+ G +
Sbjct: 91 MDLVWDNPFINWNPKECVGINKLTVLAENLWLPDIFIVESMDVDQTPSGLTAYISSEGRI 150
Query: 438 SWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNXDEMDXVIDKRIYSMFES 599
+ K + +++ ++ + +P D Q CTF F S ++ D M +DK ++ + ++
Sbjct: 151 KYDKPMRVTSICNLDIFYFPFDQQNCTFTFSSFLYTVDSMLLGMDKEVWEITDT 204
>BC101185-1|AAI01186.1| 374|Homo sapiens HTR3E protein protein.
Length = 374
Score = 59.7 bits (138), Expect = 1e-08
Identities = 29/114 (25%), Positives = 58/114 (50%), Gaps = 1/114 (0%)
Frame = +3
Query: 261 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 437
L+M W + +SWN E G + ++++ LW PD+ ++ L A VSN G +
Sbjct: 20 LEMVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEGRI 79
Query: 438 SWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNXDEMDXVIDKRIYSMFES 599
+ K + + + ++ + +P D Q CT F S ++ D M ++K ++ + ++
Sbjct: 80 RYKKPMKVDSICNLDIFYFPFDQQNCTLTFSSFLYTVDSMLLDMEKEVWEITDA 133
>BC101183-1|AAI01184.1| 471|Homo sapiens 5-hydroxytryptamine
(serotonin) receptor 3, family member E protein.
Length = 471
Score = 59.7 bits (138), Expect = 1e-08
Identities = 29/114 (25%), Positives = 58/114 (50%), Gaps = 1/114 (0%)
Frame = +3
Query: 261 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 437
L+M W + +SWN E G + ++++ LW PD+ ++ L A VSN G +
Sbjct: 106 LEMVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEGRI 165
Query: 438 SWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNXDEMDXVIDKRIYSMFES 599
+ K + + + ++ + +P D Q CT F S ++ D M ++K ++ + ++
Sbjct: 166 RYKKPMKVDSICNLDIFYFPFDQQNCTLTFSSFLYTVDSMLLDMEKEVWEITDA 219
>BC101182-1|AAI01183.1| 471|Homo sapiens 5-hydroxytryptamine
(serotonin) receptor 3, family member E protein.
Length = 471
Score = 59.7 bits (138), Expect = 1e-08
Identities = 29/114 (25%), Positives = 58/114 (50%), Gaps = 1/114 (0%)
Frame = +3
Query: 261 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 437
L+M W + +SWN E G + ++++ LW PD+ ++ L A VSN G +
Sbjct: 106 LEMVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEGRI 165
Query: 438 SWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNXDEMDXVIDKRIYSMFES 599
+ K + + + ++ + +P D Q CT F S ++ D M ++K ++ + ++
Sbjct: 166 RYKKPMKVDSICNLDIFYFPFDQQNCTLTFSSFLYTVDSMLLDMEKEVWEITDA 219
>AY159813-1|AAO38167.2| 471|Homo sapiens 5-hydroxytryptamine
serotonin receptor 3E protein.
Length = 471
Score = 59.7 bits (138), Expect = 1e-08
Identities = 29/114 (25%), Positives = 58/114 (50%), Gaps = 1/114 (0%)
Frame = +3
Query: 261 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 437
L+M W + +SWN E G + ++++ LW PD+ ++ L A VSN G +
Sbjct: 106 LEMVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEGRI 165
Query: 438 SWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNXDEMDXVIDKRIYSMFES 599
+ K + + + ++ + +P D Q CT F S ++ D M ++K ++ + ++
Sbjct: 166 RYKKPMKVDSICNLDIFYFPFDQQNCTLTFSSFLYTVDSMLLDMEKEVWEITDA 219
>AF459285-1|AAL66182.1| 447|Homo sapiens 5-hydroxytryptamine
receptor 3 subunit C protein.
Length = 447
Score = 59.3 bits (137), Expect = 2e-08
Identities = 28/114 (24%), Positives = 58/114 (50%), Gaps = 1/114 (0%)
Frame = +3
Query: 261 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 437
+ + W + ++WN E G + V +E LW PD+ ++ + L A +S+ G +
Sbjct: 91 MDLVWDNPFINWNPKECVGINKLTVLAENLWLPDIFIVESMDVDQTPSGLTAYISSEGRI 150
Query: 438 SWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNXDEMDXVIDKRIYSMFES 599
+ K + +++ + + +P D Q CTF F S ++ D M +DK ++ + ++
Sbjct: 151 KYDKPMRVTSICKLDIFYFPFDQQNCTFTFSSFLYTVDSMLLGMDKEVWEITDT 204
>X01715-1|CAA25861.1| 520|Homo sapiens acetylcholine receptor gamma
chain precursor protein.
Length = 520
Score = 58.8 bits (136), Expect = 2e-08
Identities = 42/152 (27%), Positives = 72/152 (47%), Gaps = 8/152 (5%)
Frame = +3
Query: 129 MIDSLLATYDRDSPPDSKI--VVNLTPHLRHANI---RESESTMRIQADLQMNWIDKRLS 293
++ L+ YD + P + VVN++ L N+ E E + ++M W D RL
Sbjct: 32 LLADLMQNYDPNLRPAERDSDVVNVSLKLTLTNLISLNEREEALTTNVWIEMQWCDYRLR 91
Query: 294 WNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARV--SNNGSVSWIKRLDIS 464
W+ ++ G V S +WRPD+VL N + AL V S +G + W+
Sbjct: 92 WDPRDYEGLWVLRVPSTMVWRPDIVLENNVDGVF-EVALYCNVLVSPDGCIYWLPPAIFR 150
Query: 465 TPISMQLDNWPNDMQTCTFKFGSRMHNXDEMD 560
+ S+ + +P D Q C+ F S+ ++ +E+D
Sbjct: 151 SACSISVTYFPFDWQNCSLIFQSQTYSTNEID 182
>AC092165-3|AAY24103.1| 520|Homo sapiens unknown protein.
Length = 520
Score = 58.8 bits (136), Expect = 2e-08
Identities = 42/152 (27%), Positives = 72/152 (47%), Gaps = 8/152 (5%)
Frame = +3
Query: 129 MIDSLLATYDRDSPPDSKI--VVNLTPHLRHANI---RESESTMRIQADLQMNWIDKRLS 293
++ L+ YD + P + VVN++ L N+ E E + ++M W D RL
Sbjct: 32 LLADLMQNYDPNLRPAERDSDVVNVSLKLTLTNLISLNEREEALTTNVWIEMQWCDYRLR 91
Query: 294 WNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARV--SNNGSVSWIKRLDIS 464
W+ ++ G V S +WRPD+VL N + AL V S +G + W+
Sbjct: 92 WDPRDYEGLWVLRVPSTMVWRPDIVLENNVDGVF-EVALYCNVLVSPDGCIYWLPPAIFR 150
Query: 465 TPISMQLDNWPNDMQTCTFKFGSRMHNXDEMD 560
+ S+ + +P D Q C+ F S+ ++ +E+D
Sbjct: 151 SACSISVTYFPFDWQNCSLIFQSQTYSTNEID 182
>Y00762-1|CAA68731.1| 457|Homo sapiens protein ( Human mRNA for
muscle acetylcholine receptor alpha-subunit. ).
Length = 457
Score = 58.0 bits (134), Expect = 4e-08
Identities = 37/138 (26%), Positives = 66/138 (47%), Gaps = 8/138 (5%)
Frame = +3
Query: 219 NIRESESTMRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAG 395
N+ E + L+ W+D L WN ++G + + SE++WRPD+VL N A G
Sbjct: 62 NVDEVNQIVTTNVRLKQQWVDYNLKWNPDDYGGVKKIHIPSEKIWRPDLVLYNNA---DG 118
Query: 396 DYAL----RARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNXD--EM 557
D+A+ + + G ++W + + + ++P D Q C+ K G+ ++ +
Sbjct: 119 DFAIVKFTKVLLQYTGHITWTPPAIFKSYCEIIVTHFPFDEQNCSMKLGTWTYDGSVVAI 178
Query: 558 DXVIDKRIYSMF-ESGAW 608
+ D+ S F ESG W
Sbjct: 179 NPESDQPDLSNFMESGEW 196
>X02502-1|CAA26344.1| 457|Homo sapiens acetylcholine receptor
protein.
Length = 457
Score = 58.0 bits (134), Expect = 4e-08
Identities = 37/138 (26%), Positives = 66/138 (47%), Gaps = 8/138 (5%)
Frame = +3
Query: 219 NIRESESTMRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAG 395
N+ E + L+ W+D L WN ++G + + SE++WRPD+VL N A G
Sbjct: 62 NVDEVNQIVTTNVRLKQQWVDYNLKWNPDDYGGVKKIHIPSEKIWRPDLVLYNNA---DG 118
Query: 396 DYAL----RARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNXD--EM 557
D+A+ + + G ++W + + + ++P D Q C+ K G+ ++ +
Sbjct: 119 DFAIVKFTKVLLQYTGHITWTPPAIFKSYCEIIVTHFPFDEQNCSMKLGTWTYDGSVVAI 178
Query: 558 DXVIDKRIYSMF-ESGAW 608
+ D+ S F ESG W
Sbjct: 179 NPESDQPDLSNFMESGEW 196
>S77094-1|AAD14247.1| 457|Homo sapiens nicotinic acetylcholine
receptor alpha subunit|AChR protein.
Length = 457
Score = 58.0 bits (134), Expect = 4e-08
Identities = 37/138 (26%), Positives = 66/138 (47%), Gaps = 8/138 (5%)
Frame = +3
Query: 219 NIRESESTMRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAG 395
N+ E + L+ W+D L WN ++G + + SE++WRPD+VL N A G
Sbjct: 62 NVDEVNQIVTTNVRLKQQWVDYNLKWNPDDYGGVKKIHIPSEKIWRPDLVLYNNA---DG 118
Query: 396 DYAL----RARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNXD--EM 557
D+A+ + + G ++W + + + ++P D Q C+ K G+ ++ +
Sbjct: 119 DFAIVKFTKVLLQYTGHITWTPPAIFKSYCEIIVTHFPFDEQNCSMKLGTWTYDGSVVAI 178
Query: 558 DXVIDKRIYSMF-ESGAW 608
+ D+ S F ESG W
Sbjct: 179 NPESDQPDLSNFMESGEW 196
>BC006314-1|AAH06314.1| 269|Homo sapiens CHRNA1 protein protein.
Length = 269
Score = 58.0 bits (134), Expect = 4e-08
Identities = 37/138 (26%), Positives = 66/138 (47%), Gaps = 8/138 (5%)
Frame = +3
Query: 219 NIRESESTMRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAG 395
N+ E + L+ W+D L WN ++G + + SE++WRPD+VL N A G
Sbjct: 62 NVDEVNQIVTTNVRLKQQWVDYNLKWNPDDYGGVKKIHIPSEKIWRPDLVLYNNA---DG 118
Query: 396 DYAL----RARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNXD--EM 557
D+A+ + + G ++W + + + ++P D Q C+ K G+ ++ +
Sbjct: 119 DFAIVKFTKVLLQYTGHITWTPPAIFKSYCEIIVTHFPFDEQNCSMKLGTWTYDGSVVAI 178
Query: 558 DXVIDKRIYSMF-ESGAW 608
+ D+ S F ESG W
Sbjct: 179 NPESDQPDLSNFMESGEW 196
>AY349353-1|AAQ93477.1| 456|Homo sapiens 5-HT3c1 serotonin
receptor-like protein protein.
Length = 456
Score = 58.0 bits (134), Expect = 4e-08
Identities = 29/118 (24%), Positives = 59/118 (50%), Gaps = 1/118 (0%)
Frame = +3
Query: 249 IQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSN 425
+ A L + W + +SWN E G + ++++ LW PD+ ++ L A VSN
Sbjct: 87 MSAILDVVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSN 146
Query: 426 NGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNXDEMDXVIDKRIYSMFES 599
G + + K + + + ++ + +P D Q CT F S ++ D M ++K ++ + ++
Sbjct: 147 EGRIRYKKPMKVDSICNLDIFYFPFDQQNCTLTFSSFLYTVDSMLLDMEKEVWEITDA 204
>AY349352-1|AAQ93476.1| 441|Homo sapiens 5-HT3c1 serotonin
receptor-like protein protein.
Length = 441
Score = 58.0 bits (134), Expect = 4e-08
Identities = 29/118 (24%), Positives = 59/118 (50%), Gaps = 1/118 (0%)
Frame = +3
Query: 249 IQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSN 425
+ A L + W + +SWN E G + ++++ LW PD+ ++ L A VSN
Sbjct: 72 MSAILDVVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSN 131
Query: 426 NGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNXDEMDXVIDKRIYSMFES 599
G + + K + + + ++ + +P D Q CT F S ++ D M ++K ++ + ++
Sbjct: 132 EGRIRYKKPMKVDSICNLDIFYFPFDQQNCTLTFSSFLYTVDSMLLDMEKEVWEITDA 189
>AC018890-1|AAY14687.1| 457|Homo sapiens unknown protein.
Length = 457
Score = 58.0 bits (134), Expect = 4e-08
Identities = 37/138 (26%), Positives = 66/138 (47%), Gaps = 8/138 (5%)
Frame = +3
Query: 219 NIRESESTMRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAG 395
N+ E + L+ W+D L WN ++G + + SE++WRPD+VL N A G
Sbjct: 62 NVDEVNQIVTTNVRLKQQWVDYNLKWNPDDYGGVKKIHIPSEKIWRPDLVLYNNA---DG 118
Query: 396 DYAL----RARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNXD--EM 557
D+A+ + + G ++W + + + ++P D Q C+ K G+ ++ +
Sbjct: 119 DFAIVKFTKVLLQYTGHITWTPPAIFKSYCEIIVTHFPFDEQNCSMKLGTWTYDGSVVAI 178
Query: 558 DXVIDKRIYSMF-ESGAW 608
+ D+ S F ESG W
Sbjct: 179 NPESDQPDLSNFMESGEW 196
>X55019-1|CAA38759.1| 517|Homo sapiens acetylcholine receptor delta
subunit protein.
Length = 517
Score = 56.0 bits (129), Expect = 2e-07
Identities = 31/115 (26%), Positives = 54/115 (46%), Gaps = 2/115 (1%)
Frame = +3
Query: 219 NIRESESTMRIQADLQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVL-LNAAATTA 392
+++E E T+ ++ W D RL WNA E+G S + + +W P++VL N +
Sbjct: 65 SLKEVEETLTTNVWIEHGWTDNRLKWNAEEFGNISVLRLPPDMVWLPEIVLENNNDGSFQ 124
Query: 393 GDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNXDEM 557
Y+ V + G V W+ + + + +P D Q C+ KF S + E+
Sbjct: 125 ISYSCNVLVYHYGFVYWLPPAIFRSSCPISVTYFPFDWQNCSLKFSSLKYTAKEI 179
>BC093925-1|AAH93925.1| 517|Homo sapiens cholinergic receptor,
nicotinic, delta protein.
Length = 517
Score = 56.0 bits (129), Expect = 2e-07
Identities = 31/115 (26%), Positives = 54/115 (46%), Gaps = 2/115 (1%)
Frame = +3
Query: 219 NIRESESTMRIQADLQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVL-LNAAATTA 392
+++E E T+ ++ W D RL WNA E+G S + + +W P++VL N +
Sbjct: 65 SLKEVEETLTTNVWIEHGWTDNRLKWNAEEFGNISVLRLPPDMVWLPEIVLENNNDGSFQ 124
Query: 393 GDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNXDEM 557
Y+ V + G V W+ + + + +P D Q C+ KF S + E+
Sbjct: 125 ISYSCNVLVYHYGFVYWLPPAIFRSSCPISVTYFPFDWQNCSLKFSSLKYTAKEI 179
>BC093923-1|AAH93923.1| 517|Homo sapiens cholinergic receptor,
nicotinic, delta protein.
Length = 517
Score = 56.0 bits (129), Expect = 2e-07
Identities = 31/115 (26%), Positives = 54/115 (46%), Gaps = 2/115 (1%)
Frame = +3
Query: 219 NIRESESTMRIQADLQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVL-LNAAATTA 392
+++E E T+ ++ W D RL WNA E+G S + + +W P++VL N +
Sbjct: 65 SLKEVEETLTTNVWIEHGWTDNRLKWNAEEFGNISVLRLPPDMVWLPEIVLENNNDGSFQ 124
Query: 393 GDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNXDEM 557
Y+ V + G V W+ + + + +P D Q C+ KF S + E+
Sbjct: 125 ISYSCNVLVYHYGFVYWLPPAIFRSSCPISVTYFPFDWQNCSLKFSSLKYTAKEI 179
>AC092165-2|AAY24102.1| 517|Homo sapiens unknown protein.
Length = 517
Score = 56.0 bits (129), Expect = 2e-07
Identities = 31/115 (26%), Positives = 54/115 (46%), Gaps = 2/115 (1%)
Frame = +3
Query: 219 NIRESESTMRIQADLQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVL-LNAAATTA 392
+++E E T+ ++ W D RL WNA E+G S + + +W P++VL N +
Sbjct: 65 SLKEVEETLTTNVWIEHGWTDNRLKWNAEEFGNISVLRLPPDMVWLPEIVLENNNDGSFQ 124
Query: 393 GDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNXDEM 557
Y+ V + G V W+ + + + +P D Q C+ KF S + E+
Sbjct: 125 ISYSCNVLVYHYGFVYWLPPAIFRSSCPISVTYFPFDWQNCSLKFSSLKYTAKEI 179
>AJ295237-1|CAC16144.1| 450|Homo sapiens neuronal nicotinic
acetylcholine receptor subunit4 protein.
Length = 450
Score = 54.4 bits (125), Expect = 5e-07
Identities = 44/165 (26%), Positives = 70/165 (42%), Gaps = 10/165 (6%)
Frame = +3
Query: 96 AEC---ENATSLSLMIDSLLATYDRDSPP--DSKIVVNLTPHLRHANI---RESESTMRI 251
AEC E +L L D L A Y P D+ +N+T + + I E + +
Sbjct: 20 AECLGAEGRLALKLFRD-LFANYTSALRPVADTDQTLNVTLEVTLSQIIDMDERNQVLTL 78
Query: 252 QADLQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSN 425
++ W D L W+ +G + S +WRPD+VL N A A G + + +
Sbjct: 79 YLWIRQEWTDAYLRWDPNAYGGLDAIRIPSSLVWRPDIVLYNKADAQPPGSASTNVVLRH 138
Query: 426 NGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNXDEMD 560
+G+V W + + + +P D Q C FGS H ++D
Sbjct: 139 DGAVRWDAPAITRSSCRVDVAAFPFDAQHCGLTFGSWTHGGHQLD 183
>AJ278118-1|CAC20435.1| 450|Homo sapiens neuronal nicotinic
acetylcholine alpha10 subunit protein.
Length = 450
Score = 54.4 bits (125), Expect = 5e-07
Identities = 44/165 (26%), Positives = 70/165 (42%), Gaps = 10/165 (6%)
Frame = +3
Query: 96 AEC---ENATSLSLMIDSLLATYDRDSPP--DSKIVVNLTPHLRHANI---RESESTMRI 251
AEC E +L L D L A Y P D+ +N+T + + I E + +
Sbjct: 20 AECLGAEGRLALKLFRD-LFANYTSALRPVADTDQTLNVTLEVTLSQIIDMDERNQVLTL 78
Query: 252 QADLQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSN 425
++ W D L W+ +G + S +WRPD+VL N A A G + + +
Sbjct: 79 YLWIRQEWTDAYLRWDPNAYGGLDAIRIPSSLVWRPDIVLYNKADAQPPGSASTNVVLRH 138
Query: 426 NGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNXDEMD 560
+G+V W + + + +P D Q C FGS H ++D
Sbjct: 139 DGAVRWDAPAITRSSCRVDVAAFPFDAQHCGLTFGSWTHGGHQLD 183
>AF327367-1|AAK14333.1| 450|Homo sapiens nicotinic acetylcholine
receptor subunit alpha 10 protein.
Length = 450
Score = 54.4 bits (125), Expect = 5e-07
Identities = 44/165 (26%), Positives = 70/165 (42%), Gaps = 10/165 (6%)
Frame = +3
Query: 96 AEC---ENATSLSLMIDSLLATYDRDSPP--DSKIVVNLTPHLRHANI---RESESTMRI 251
AEC E +L L D L A Y P D+ +N+T + + I E + +
Sbjct: 20 AECLGAEGRLALKLFRD-LFANYTSALRPVADTDQTLNVTLEVTLSQIIDMDERNQVLTL 78
Query: 252 QADLQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSN 425
++ W D L W+ +G + S +WRPD+VL N A A G + + +
Sbjct: 79 YLWIRQEWTDAYLRWDPNAYGGLDAIRIPSSLVWRPDIVLYNKADAQPPGSASTNVVLRH 138
Query: 426 NGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNXDEMD 560
+G+V W + + + +P D Q C FGS H ++D
Sbjct: 139 DGAVRWDAPAITRSSCRVDVAAFPFDAQHCGLTFGSWTHGGHQLD 183
>AF199235-1|AAG00795.2| 450|Homo sapiens nicotinic acetylcholine
receptor subunit alpha 10 protein.
Length = 450
Score = 54.4 bits (125), Expect = 5e-07
Identities = 44/165 (26%), Positives = 70/165 (42%), Gaps = 10/165 (6%)
Frame = +3
Query: 96 AEC---ENATSLSLMIDSLLATYDRDSPP--DSKIVVNLTPHLRHANI---RESESTMRI 251
AEC E +L L D L A Y P D+ +N+T + + I E + +
Sbjct: 20 AECLGAEGRLALKLFRD-LFANYTSALRPVADTDQTLNVTLEVTLSQIIDMDERNQVLTL 78
Query: 252 QADLQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSN 425
++ W D L W+ +G + S +WRPD+VL N A A G + + +
Sbjct: 79 YLWIRQEWTDAYLRWDPNAYGGLDAIRIPSSLVWRPDIVLYNKADAQPPGSASTNVVLRH 138
Query: 426 NGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNXDEMD 560
+G+V W + + + +P D Q C FGS H ++D
Sbjct: 139 DGAVRWDAPAITRSSCRVDVAAFPFDAQHCGLTFGSWTHGGHQLD 183
>Z23141-1|CAA80672.1| 479|Homo sapiens cholinergic receptor,
nicotinic, alpha polypeptide 7 protein.
Length = 479
Score = 54.0 bits (124), Expect = 6e-07
Identities = 34/141 (24%), Positives = 62/141 (43%), Gaps = 3/141 (2%)
Frame = +3
Query: 207 LRHANIRESESTMRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA- 380
L+ ++ E + LQM+W D L WN E+ G T ++W+PD++L N+A
Sbjct: 37 LQIMDVDEKNQVLTTNIWLQMSWTDHYLQWNVSEYPGVKTVRFPDGQIWKPDILLYNSAD 96
Query: 381 ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNXDEMD 560
+ V+++G ++ + + + +P D+Q C KFGS + +D
Sbjct: 97 ERFDATFHTNVLVNSSGHCQYLPPGIFKSSCYIDVRWFPFDVQHCKLKFGSWSYGGWSLD 156
Query: 561 XVIDKR-IYSMFESGAWGCDG 620
+ + I +G W G
Sbjct: 157 LQMQEADISGYIPNGEWDLVG 177
>Y08420-1|CAA69697.1| 502|Homo sapiens nicotinic acetylcholine
receptor alpha7 subunit precursor protein.
Length = 502
Score = 54.0 bits (124), Expect = 6e-07
Identities = 34/141 (24%), Positives = 62/141 (43%), Gaps = 3/141 (2%)
Frame = +3
Query: 207 LRHANIRESESTMRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA- 380
L+ ++ E + LQM+W D L WN E+ G T ++W+PD++L N+A
Sbjct: 60 LQIMDVDEKNQVLTTNIWLQMSWTDHYLQWNVSEYPGVKTVRFPDGQIWKPDILLYNSAD 119
Query: 381 ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNXDEMD 560
+ V+++G ++ + + + +P D+Q C KFGS + +D
Sbjct: 120 ERFDATFHTNVLVNSSGHCQYLPPGIFKSSCYIDVRWFPFDVQHCKLKFGSWSYGGWSLD 179
Query: 561 XVIDKR-IYSMFESGAWGCDG 620
+ + I +G W G
Sbjct: 180 LQMQEADISGYIPNGEWDLVG 200
>X70297-1|CAA49778.1| 502|Homo sapiens neuronal nicotinic
acetylocholine receptor alpha-7 subunit protein.
Length = 502
Score = 54.0 bits (124), Expect = 6e-07
Identities = 34/141 (24%), Positives = 62/141 (43%), Gaps = 3/141 (2%)
Frame = +3
Query: 207 LRHANIRESESTMRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA- 380
L+ ++ E + LQM+W D L WN E+ G T ++W+PD++L N+A
Sbjct: 60 LQIMDVDEKNQVLTTNIWLQMSWTDHYLQWNVSEYPGVKTVRFPDGQIWKPDILLYNSAD 119
Query: 381 ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNXDEMD 560
+ V+++G ++ + + + +P D+Q C KFGS + +D
Sbjct: 120 ERFDATFHTNVLVNSSGHCQYLPPGIFKSSCYIDVRWFPFDVQHCKLKFGSWSYGGWSLD 179
Query: 561 XVIDKR-IYSMFESGAWGCDG 620
+ + I +G W G
Sbjct: 180 LQMQEADISGYIPNGEWDLVG 200
>U62436-1|AAB40114.1| 502|Homo sapiens nicotinic acetylcholine
receptor alpha7 subunit precursor protein.
Length = 502
Score = 54.0 bits (124), Expect = 6e-07
Identities = 34/141 (24%), Positives = 62/141 (43%), Gaps = 3/141 (2%)
Frame = +3
Query: 207 LRHANIRESESTMRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA- 380
L+ ++ E + LQM+W D L WN E+ G T ++W+PD++L N+A
Sbjct: 60 LQIMDVDEKNQVLTTNIWLQMSWTDHYLQWNVSEYPGVKTVRFPDGQIWKPDILLYNSAD 119
Query: 381 ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNXDEMD 560
+ V+++G ++ + + + +P D+Q C KFGS + +D
Sbjct: 120 ERFDATFHTNVLVNSSGHCQYLPPGIFKSSCYIDVRWFPFDVQHCKLKFGSWSYGGWSLD 179
Query: 561 XVIDKR-IYSMFESGAWGCDG 620
+ + I +G W G
Sbjct: 180 LQMQEADISGYIPNGEWDLVG 200
>AJ586911-1|CAE52911.1| 502|Homo sapiens nicotinic acetylcholine
alpha-7 subunit protein.
Length = 502
Score = 54.0 bits (124), Expect = 6e-07
Identities = 34/141 (24%), Positives = 62/141 (43%), Gaps = 3/141 (2%)
Frame = +3
Query: 207 LRHANIRESESTMRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA- 380
L+ ++ E + LQM+W D L WN E+ G T ++W+PD++L N+A
Sbjct: 60 LQIMDVDEKNQVLTTNIWLQMSWTDHYLQWNVSEYPGVKTVRFPDGQIWKPDILLYNSAD 119
Query: 381 ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNXDEMD 560
+ V+++G ++ + + + +P D+Q C KFGS + +D
Sbjct: 120 ERFDATFHTNVLVNSSGHCQYLPPGIFKSSCYIDVRWFPFDVQHCKLKFGSWSYGGWSLD 179
Query: 561 XVIDKR-IYSMFESGAWGCDG 620
+ + I +G W G
Sbjct: 180 LQMQEADISGYIPNGEWDLVG 200
>BC113575-1|AAI13576.1| 479|Homo sapiens cholinergic receptor,
nicotinic, alpha 9 protein.
Length = 479
Score = 53.6 bits (123), Expect = 8e-07
Identities = 37/163 (22%), Positives = 74/163 (45%), Gaps = 7/163 (4%)
Frame = +3
Query: 93 AAECENATSLSLMIDSLLATYDRDSPP--DSKIVVNLTPHLRHANIRESESTMRIQAD-- 260
AAE + + + L Y P D+ V+N+T + + I++ + +I
Sbjct: 22 AAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQITLSQIKDMDERNQILTAYL 81
Query: 261 -LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGD-YALRARVSNNG 431
++ W D L+W+ ++ G + + S+ +WRPD+VL N A + + + +G
Sbjct: 82 WIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKADDESSEPVNTNVVLRYDG 141
Query: 432 SVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNXDEMD 560
++W + + + +P D Q C FGS +N +++D
Sbjct: 142 LITWDAPAITKSSCVVDVTYFPFDNQQCNLTFGSWTYNGNQVD 184
>BC113549-1|AAI13550.1| 479|Homo sapiens cholinergic receptor,
nicotinic, alpha 9 protein.
Length = 479
Score = 53.6 bits (123), Expect = 8e-07
Identities = 37/163 (22%), Positives = 74/163 (45%), Gaps = 7/163 (4%)
Frame = +3
Query: 93 AAECENATSLSLMIDSLLATYDRDSPP--DSKIVVNLTPHLRHANIRESESTMRIQAD-- 260
AAE + + + L Y P D+ V+N+T + + I++ + +I
Sbjct: 22 AAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQITLSQIKDMDERNQILTAYL 81
Query: 261 -LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGD-YALRARVSNNG 431
++ W D L+W+ ++ G + + S+ +WRPD+VL N A + + + +G
Sbjct: 82 WIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKADDESSEPVNTNVVLRYDG 141
Query: 432 SVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNXDEMD 560
++W + + + +P D Q C FGS +N +++D
Sbjct: 142 LITWDAPAITKSSCVVDVTYFPFDNQQCNLTFGSWTYNGNQVD 184
>AY123244-1|AAM74523.1| 479|Homo sapiens nicotinic acetylcholine
receptor subunit alpha 9 protein.
Length = 479
Score = 53.6 bits (123), Expect = 8e-07
Identities = 37/163 (22%), Positives = 74/163 (45%), Gaps = 7/163 (4%)
Frame = +3
Query: 93 AAECENATSLSLMIDSLLATYDRDSPP--DSKIVVNLTPHLRHANIRESESTMRIQAD-- 260
AAE + + + L Y P D+ V+N+T + + I++ + +I
Sbjct: 22 AAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQITLSQIKDMDERNQILTAYL 81
Query: 261 -LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGD-YALRARVSNNG 431
++ W D L+W+ ++ G + + S+ +WRPD+VL N A + + + +G
Sbjct: 82 WIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKADDESSEPVNTNVVLRYDG 141
Query: 432 SVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNXDEMD 560
++W + + + +P D Q C FGS +N +++D
Sbjct: 142 LITWDAPAITKSSCVVDVTYFPFDNQQCNLTFGSWTYNGNQVD 184
>AJ243342-1|CAB65091.1| 479|Homo sapiens nicotinic acetylcholine
receptor alpha 9 subunit protein.
Length = 479
Score = 53.6 bits (123), Expect = 8e-07
Identities = 37/163 (22%), Positives = 74/163 (45%), Gaps = 7/163 (4%)
Frame = +3
Query: 93 AAECENATSLSLMIDSLLATYDRDSPP--DSKIVVNLTPHLRHANIRESESTMRIQAD-- 260
AAE + + + L Y P D+ V+N+T + + I++ + +I
Sbjct: 22 AAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQITLSQIKDMDERNQILTAYL 81
Query: 261 -LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGD-YALRARVSNNG 431
++ W D L+W+ ++ G + + S+ +WRPD+VL N A + + + +G
Sbjct: 82 WIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKADDESSEPVNTNVVLRYDG 141
Query: 432 SVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNXDEMD 560
++W + + + +P D Q C FGS +N +++D
Sbjct: 142 LITWDAPAITKSSCVVDVTYFPFDNQQCNLTFGSWTYNGNQVD 184
>AF227732-1|AAF61920.1| 470|Homo sapiens nicotinic acetylcholine
receptor alpha 9 subunit protein.
Length = 470
Score = 53.6 bits (123), Expect = 8e-07
Identities = 37/163 (22%), Positives = 74/163 (45%), Gaps = 7/163 (4%)
Frame = +3
Query: 93 AAECENATSLSLMIDSLLATYDRDSPP--DSKIVVNLTPHLRHANIRESESTMRIQAD-- 260
AAE + + + L Y P D+ V+N+T + + I++ + +I
Sbjct: 16 AAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQITLSQIKDMDERNQILTAYL 75
Query: 261 -LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGD-YALRARVSNNG 431
++ W D L+W+ ++ G + + S+ +WRPD+VL N A + + + +G
Sbjct: 76 WIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKADDESSEPVNTNVVLRYDG 135
Query: 432 SVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNXDEMD 560
++W + + + +P D Q C FGS +N +++D
Sbjct: 136 LITWDAPAITKSSCVVDVTYFPFDNQQCNLTFGSWTYNGNQVD 178
>AC118275-1|AAY40986.1| 479|Homo sapiens unknown protein.
Length = 479
Score = 53.6 bits (123), Expect = 8e-07
Identities = 37/163 (22%), Positives = 74/163 (45%), Gaps = 7/163 (4%)
Frame = +3
Query: 93 AAECENATSLSLMIDSLLATYDRDSPP--DSKIVVNLTPHLRHANIRESESTMRIQAD-- 260
AAE + + + L Y P D+ V+N+T + + I++ + +I
Sbjct: 22 AAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQITLSQIKDMDERNQILTAYL 81
Query: 261 -LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGD-YALRARVSNNG 431
++ W D L+W+ ++ G + + S+ +WRPD+VL N A + + + +G
Sbjct: 82 WIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKADDESSEPVNTNVVLRYDG 141
Query: 432 SVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNXDEMD 560
++W + + + +P D Q C FGS +N +++D
Sbjct: 142 LITWDAPAITKSSCVVDVTYFPFDNQQCNLTFGSWTYNGNQVD 184
>U40583-1|AAA83561.1| 502|Homo sapiens alpha 7 neuronal nicotinic
acetylcholine receptor protein.
Length = 502
Score = 52.8 bits (121), Expect = 1e-06
Identities = 34/141 (24%), Positives = 61/141 (43%), Gaps = 3/141 (2%)
Frame = +3
Query: 207 LRHANIRESESTMRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA- 380
L+ ++ E + LQM+W D L WN E+ G T ++W+PD++L N+A
Sbjct: 60 LQIMDVDEKNQVLTTNIWLQMSWTDHYLQWNVSEYPGVKTVRFPDGQIWKPDILLYNSAD 119
Query: 381 ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNXDEMD 560
+ V+ +G ++ + + + +P D+Q C KFGS + +D
Sbjct: 120 ERFDATFHTNVLVNPSGHCQYLPPGIFKSSCYIDVRWFPFDVQHCKLKFGSWSYGGWSLD 179
Query: 561 XVIDKR-IYSMFESGAWGCDG 620
+ + I +G W G
Sbjct: 180 LQMQEADISGYIPNGEWDLVG 200
>AF385585-1|AAK68111.1| 502|Homo sapiens nicotinic cholinergic
receptor alpha 7 protein.
Length = 502
Score = 52.8 bits (121), Expect = 1e-06
Identities = 34/141 (24%), Positives = 61/141 (43%), Gaps = 3/141 (2%)
Frame = +3
Query: 207 LRHANIRESESTMRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA- 380
L+ ++ E + LQM+W D L WN E+ G T ++W+PD++L N+A
Sbjct: 60 LQIMDVDEKNQVLTTNIWLQMSWTDHYLQWNVSEYPGVKTVRFPDGQIWKPDILLYNSAD 119
Query: 381 ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNXDEMD 560
+ V+ +G ++ + + + +P D+Q C KFGS + +D
Sbjct: 120 ERFDATFHTNVLVNPSGHCQYLPPGIFKSSCYIDVRWFPFDVQHCKLKFGSWSYGGWSLD 179
Query: 561 XVIDKR-IYSMFESGAWGCDG 620
+ + I +G W G
Sbjct: 180 LQMQEADISGYIPNGEWDLVG 200
>BC110597-1|AAI10598.1| 411|Homo sapiens ligand-gated ion channel,
zinc activated 1 protein.
Length = 411
Score = 52.0 bits (119), Expect = 3e-06
Identities = 29/107 (27%), Positives = 49/107 (45%)
Frame = +3
Query: 240 TMRIQADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARV 419
TM L+++W+D RL+WN + E LW P + +L A D + +ARV
Sbjct: 79 TMSSMLLLRLSWLDTRLAWNTSAHPRHAITLPWESLWTPRLTILEALWVDWRDQSPQARV 138
Query: 420 SNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNXDEMD 560
+G V L T + +L ++P D C+ F + + E++
Sbjct: 139 DQDGHVKLNLALTTETNCNFELLHFPRDHSNCSLSFYALSNTAMELE 185
>AF512521-1|AAO20969.1| 411|Homo sapiens ligand-gated ion channel
subunit protein.
Length = 411
Score = 52.0 bits (119), Expect = 3e-06
Identities = 29/107 (27%), Positives = 49/107 (45%)
Frame = +3
Query: 240 TMRIQADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARV 419
TM L+++W+D RL+WN + E LW P + +L A D + +ARV
Sbjct: 79 TMSSMLLLRLSWLDTRLAWNTSAHPRHAITLPWESLWTPRLTILEALWVDWRDQSPQARV 138
Query: 420 SNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNXDEMD 560
+G V L T + +L ++P D C+ F + + E++
Sbjct: 139 DQDGHVKLNLALTTETNCNFELLHFPRDHSNCSLSFYALSNTAMELE 185
>L08485-1|AAA58490.1| 462|Homo sapiens GABA-benzodiazepine receptor
alpha-5-subunit protein.
Length = 462
Score = 51.6 bits (118), Expect = 3e-06
Identities = 37/158 (23%), Positives = 70/158 (44%), Gaps = 7/158 (4%)
Frame = +3
Query: 105 ENATSLSLMIDSLLATYD-RDSPPDSKIVVNLTPHLRHAN---IRESESTMRIQADLQMN 272
+N T + ++D LL YD R P + + + + + + ++E I + +
Sbjct: 44 DNITIFTRILDGLLDGYDNRLRPGLGERITQVRTDIYVTSFGPVSDTEMEYTIDVFFRQS 103
Query: 273 WIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSW 443
W D+RL + + + ++W PD N + A + R+ ++G++ +
Sbjct: 104 WKDERLRFKGPMQRLPLNNLLASKIWTPDTFFHNGKKSIAHNMTTPNKLLRLEDDGTLLY 163
Query: 444 IKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNXDEM 557
RL IS MQL+++P D C KFGS + E+
Sbjct: 164 TMRLTISAECPMQLEDFPMDAHACPLKFGSYAYPNSEV 201
>BT009830-1|AAP88832.1| 462|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 5 protein.
Length = 462
Score = 51.6 bits (118), Expect = 3e-06
Identities = 37/158 (23%), Positives = 70/158 (44%), Gaps = 7/158 (4%)
Frame = +3
Query: 105 ENATSLSLMIDSLLATYD-RDSPPDSKIVVNLTPHLRHAN---IRESESTMRIQADLQMN 272
+N T + ++D LL YD R P + + + + + + ++E I + +
Sbjct: 44 DNITIFTRILDGLLDGYDNRLRPGLGERITQVRTDIYVTSFGPVSDTEMEYTIDVFFRQS 103
Query: 273 WIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSW 443
W D+RL + + + ++W PD N + A + R+ ++G++ +
Sbjct: 104 WKDERLRFKGPMQRLPLNNLLASKIWTPDTFFHNGKKSIAHNMTTPNKLLRLEDDGTLLY 163
Query: 444 IKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNXDEM 557
RL IS MQL+++P D C KFGS + E+
Sbjct: 164 TMRLTISAECPMQLEDFPMDAHACPLKFGSYAYPNSEV 201
>BC113422-1|AAI13423.1| 462|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 5 protein.
Length = 462
Score = 51.6 bits (118), Expect = 3e-06
Identities = 37/158 (23%), Positives = 70/158 (44%), Gaps = 7/158 (4%)
Frame = +3
Query: 105 ENATSLSLMIDSLLATYD-RDSPPDSKIVVNLTPHLRHAN---IRESESTMRIQADLQMN 272
+N T + ++D LL YD R P + + + + + + ++E I + +
Sbjct: 44 DNITIFTRILDGLLDGYDNRLRPGLGERITQVRTDIYVTSFGPVSDTEMEYTIDVFFRQS 103
Query: 273 WIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSW 443
W D+RL + + + ++W PD N + A + R+ ++G++ +
Sbjct: 104 WKDERLRFKGPMQRLPLNNLLASKIWTPDTFFHNGKKSIAHNMTTPNKLLRLEDDGTLLY 163
Query: 444 IKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNXDEM 557
RL IS MQL+++P D C KFGS + E+
Sbjct: 164 TMRLTISAECPMQLEDFPMDAHACPLKFGSYAYPNSEV 201
>BC111979-1|AAI11980.1| 462|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 5, precursor protein.
Length = 462
Score = 51.6 bits (118), Expect = 3e-06
Identities = 37/158 (23%), Positives = 70/158 (44%), Gaps = 7/158 (4%)
Frame = +3
Query: 105 ENATSLSLMIDSLLATYD-RDSPPDSKIVVNLTPHLRHAN---IRESESTMRIQADLQMN 272
+N T + ++D LL YD R P + + + + + + ++E I + +
Sbjct: 44 DNITIFTRILDGLLDGYDNRLRPGLGERITQVRTDIYVTSFGPVSDTEMEYTIDVFFRQS 103
Query: 273 WIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSW 443
W D+RL + + + ++W PD N + A + R+ ++G++ +
Sbjct: 104 WKDERLRFKGPMQRLPLNNLLASKIWTPDTFFHNGKKSIAHNMTTPNKLLRLEDDGTLLY 163
Query: 444 IKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNXDEM 557
RL IS MQL+++P D C KFGS + E+
Sbjct: 164 TMRLTISAECPMQLEDFPMDAHACPLKFGSYAYPNSEV 201
>AK122638-1|BAC85499.1| 266|Homo sapiens yte protein of 76kDa)
(LCP2). protein.
Length = 266
Score = 51.6 bits (118), Expect = 3e-06
Identities = 28/96 (29%), Positives = 44/96 (45%)
Frame = +3
Query: 240 TMRIQADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARV 419
TM L+++W+D RL+WN + E LW P + +L A D + +ARV
Sbjct: 80 TMSSMLLLRLSWLDTRLAWNTSAHPRHAITLPWESLWTPRLTILEALWVDWRDQSPQARV 139
Query: 420 SNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKF 527
+G V L T + +L ++P D C+ F
Sbjct: 140 DQDGHVKLNLALTTETNCNFELLHFPRDHSNCSLSF 175
>AB223030-1|BAE19924.1| 411|Homo sapiens ligand-gated ion-channel
receptor L2 protein.
Length = 411
Score = 51.6 bits (118), Expect = 3e-06
Identities = 29/107 (27%), Positives = 49/107 (45%)
Frame = +3
Query: 240 TMRIQADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARV 419
TM L+++W+D RL+WN + E LW P + +L A D + +ARV
Sbjct: 79 TMSSMLLLRLSWLDTRLAWNTSAHPRHAITLPWESLWTPRLTILEALWVDWRDQSPQARV 138
Query: 420 SNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNXDEMD 560
+G V L T + +L ++P D C+ F + + E++
Sbjct: 139 DQDGHVKLNLALATETNCNFELLHFPRDHSNCSLSFYALSNTAMELE 185
>S82612-1|AAB37533.2| 478|Homo sapiens 5-hydroxytryptamine type 3AS
receptor subunit protein.
Length = 478
Score = 50.4 bits (115), Expect = 8e-06
Identities = 26/115 (22%), Positives = 51/115 (44%), Gaps = 1/115 (0%)
Frame = +3
Query: 219 NIRESESTMRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAG 395
N+ E + + W D+ L WN ++ T L + ++ +W PD+++
Sbjct: 72 NVDEKNQVLTTYIWYRQYWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINELVDVGKS 131
Query: 396 DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNXDEMD 560
+ + G V K L + T S+ + N+P D+Q C+ F S +H +++
Sbjct: 132 PNIPYVYIRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLHTIQDIN 186
>D49394-1|BAA08387.1| 478|Homo sapiens serotonin 5-HT3 receptor
protein.
Length = 478
Score = 50.0 bits (114), Expect = 1e-05
Identities = 26/115 (22%), Positives = 51/115 (44%), Gaps = 1/115 (0%)
Frame = +3
Query: 219 NIRESESTMRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAG 395
N+ E + + W D+ L WN ++ T L + ++ +W PD+++
Sbjct: 72 NVDEKNQVLTTYIWYRQYWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKS 131
Query: 396 DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNXDEMD 560
+ + G V K L + T S+ + N+P D+Q C+ F S +H +++
Sbjct: 132 PNIPYVYIRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLHTIQDIN 186
>BT007204-1|AAP35868.1| 484|Homo sapiens 5-hydroxytryptamine
(serotonin) receptor 3A protein.
Length = 484
Score = 50.0 bits (114), Expect = 1e-05
Identities = 26/115 (22%), Positives = 51/115 (44%), Gaps = 1/115 (0%)
Frame = +3
Query: 219 NIRESESTMRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAG 395
N+ E + + W D+ L WN ++ T L + ++ +W PD+++
Sbjct: 78 NVDEKNQVLTTYIWYRQYWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKS 137
Query: 396 DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNXDEMD 560
+ + G V K L + T S+ + N+P D+Q C+ F S +H +++
Sbjct: 138 PNIPYVYIRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLHTIQDIN 192
>BC004453-1|AAH04453.2| 478|Homo sapiens 5-hydroxytryptamine
(serotonin) receptor 3A protein.
Length = 478
Score = 50.0 bits (114), Expect = 1e-05
Identities = 26/115 (22%), Positives = 51/115 (44%), Gaps = 1/115 (0%)
Frame = +3
Query: 219 NIRESESTMRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAG 395
N+ E + + W D+ L WN ++ T L + ++ +W PD+++
Sbjct: 72 NVDEKNQVLTTYIWYRQYWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKS 131
Query: 396 DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNXDEMD 560
+ + G V K L + T S+ + N+P D+Q C+ F S +H +++
Sbjct: 132 PNIPYVYIRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLHTIQDIN 186
>BC002354-1|AAH02354.1| 478|Homo sapiens 5-hydroxytryptamine
(serotonin) receptor 3A protein.
Length = 478
Score = 50.0 bits (114), Expect = 1e-05
Identities = 26/115 (22%), Positives = 51/115 (44%), Gaps = 1/115 (0%)
Frame = +3
Query: 219 NIRESESTMRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAG 395
N+ E + + W D+ L WN ++ T L + ++ +W PD+++
Sbjct: 72 NVDEKNQVLTTYIWYRQYWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKS 131
Query: 396 DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNXDEMD 560
+ + G V K L + T S+ + N+P D+Q C+ F S +H +++
Sbjct: 132 PNIPYVYIRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLHTIQDIN 186
>AJ005205-1|CAA06442.3| 478|Homo sapiens serotonin 3 receptor
protein.
Length = 478
Score = 50.0 bits (114), Expect = 1e-05
Identities = 26/115 (22%), Positives = 51/115 (44%), Gaps = 1/115 (0%)
Frame = +3
Query: 219 NIRESESTMRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAG 395
N+ E + + W D+ L WN ++ T L + ++ +W PD+++
Sbjct: 72 NVDEKNQVLTTYIWYRQYWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKS 131
Query: 396 DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNXDEMD 560
+ + G V K L + T S+ + N+P D+Q C+ F S +H +++
Sbjct: 132 PNIPYVYIRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLHTIQDIN 186
>AJ003079-1|CAA05852.1| 478|Homo sapiens 5-hydroxytryptamine3
receptor protein.
Length = 478
Score = 50.0 bits (114), Expect = 1e-05
Identities = 26/115 (22%), Positives = 51/115 (44%), Gaps = 1/115 (0%)
Frame = +3
Query: 219 NIRESESTMRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAG 395
N+ E + + W D+ L WN ++ T L + ++ +W PD+++
Sbjct: 72 NVDEKNQVLTTYIWYRQYWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKS 131
Query: 396 DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNXDEMD 560
+ + G V K L + T S+ + N+P D+Q C+ F S +H +++
Sbjct: 132 PNIPYVYIRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLHTIQDIN 186
>AJ003078-1|CAA05851.1| 510|Homo sapiens serotonin receptor
protein.
Length = 510
Score = 50.0 bits (114), Expect = 1e-05
Identities = 26/115 (22%), Positives = 51/115 (44%), Gaps = 1/115 (0%)
Frame = +3
Query: 219 NIRESESTMRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAG 395
N+ E + + W D+ L WN ++ T L + ++ +W PD+++
Sbjct: 72 NVDEKNQVLTTYIWYRQYWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKS 131
Query: 396 DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNXDEMD 560
+ + G V K L + T S+ + N+P D+Q C+ F S +H +++
Sbjct: 132 PNIPYVYIRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLHTIQDIN 186
>AF498984-1|AAM21131.1| 478|Homo sapiens 5-hydroxytryptamine
receptor 3A protein.
Length = 478
Score = 50.0 bits (114), Expect = 1e-05
Identities = 26/115 (22%), Positives = 51/115 (44%), Gaps = 1/115 (0%)
Frame = +3
Query: 219 NIRESESTMRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAG 395
N+ E + + W D+ L WN ++ T L + ++ +W PD+++
Sbjct: 72 NVDEKNQVLTTYIWYRQYWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKS 131
Query: 396 DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNXDEMD 560
+ + G V K L + T S+ + N+P D+Q C+ F S +H +++
Sbjct: 132 PNIPYVYIRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLHTIQDIN 186
>S82769-1|AAB39369.1| 467|Homo sapiens GABAA receptor gamma 3
subunit protein.
Length = 467
Score = 49.2 bits (112), Expect = 2e-05
Identities = 40/156 (25%), Positives = 68/156 (43%), Gaps = 8/156 (5%)
Frame = +3
Query: 114 TSLSLMIDSLLATYDRDSPPDSKI---VVNLTPHLRHANIRESESTMRIQADL--QMNWI 278
T ++L+++ LL YD+ PD I V+++ ++ S M Q D+ W
Sbjct: 45 TDVTLILNKLLREYDKKLRPDIGIKPTVIDVDIYVNSIG-PVSSINMEYQIDIFFAQTWT 103
Query: 279 DKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIK 449
D RL +N+ + +W PD + N+ A R+ N+G + +
Sbjct: 104 DSRLRFNSTMKILTLNSNMVGLIWIPDTIFRNSKTAEAHWITTPNQLLRIWNDGKILYTL 163
Query: 450 RLDISTPISMQLDNWPNDMQTCTFKFGSRMHNXDEM 557
RL I+ +QL N+P D +C F S + +EM
Sbjct: 164 RLTINAECQLQLHNFPMDEHSCPLIFSSYGYPKEEM 199
>BC028629-1|AAH28629.1| 492|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 3 protein.
Length = 492
Score = 49.2 bits (112), Expect = 2e-05
Identities = 36/158 (22%), Positives = 68/158 (43%), Gaps = 7/158 (4%)
Frame = +3
Query: 105 ENATSLSLMIDSLLATYDRDSPP---DSKIVVNLTPHLRHAN-IRESESTMRIQADLQMN 272
+N T + ++D LL YD P D+ V ++ + +++ I +
Sbjct: 62 DNITIFTRILDRLLDGYDNRLRPGLGDAVTEVKTDIYVTSFGPVSDTDMEYTIDVFFRQT 121
Query: 273 WIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSW 443
W D+RL ++ + + ++W PD N + A + R+ +NG++ +
Sbjct: 122 WHDERLKFDGPMKILPLNNLLASKIWTPDTFFHNGKKSVAHNMTTPNKLLRLVDNGTLPY 181
Query: 444 IKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNXDEM 557
RL I M L+++P D+ C KFGS + E+
Sbjct: 182 TMRLTIHAECPMHLEDFPMDVHACPLKFGSYAYTTAEV 219
>AF269144-1|AAF99698.1| 467|Homo sapiens GABAA receptor gamma 3
subunit protein.
Length = 467
Score = 49.2 bits (112), Expect = 2e-05
Identities = 40/156 (25%), Positives = 68/156 (43%), Gaps = 8/156 (5%)
Frame = +3
Query: 114 TSLSLMIDSLLATYDRDSPPDSKI---VVNLTPHLRHANIRESESTMRIQADL--QMNWI 278
T ++L+++ LL YD+ PD I V+++ ++ S M Q D+ W
Sbjct: 45 TDVTLILNKLLREYDKKLRPDIGIKPTVIDVDIYVNSIG-PVSSINMEYQIDIFFAQTWT 103
Query: 279 DKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIK 449
D RL +N+ + +W PD + N+ A R+ N+G + +
Sbjct: 104 DSRLRFNSTMKILTLNSNMVGLIWIPDTIFRNSKTAEAHWITTPNQLLRIWNDGKILYTL 163
Query: 450 RLDISTPISMQLDNWPNDMQTCTFKFGSRMHNXDEM 557
RL I+ +QL N+P D +C F S + +EM
Sbjct: 164 RLTINAECQLQLHNFPMDEHSCPLIFSSYGYPKEEM 199
>AF228458-1|AAF63215.1| 449|Homo sapiens GABAA receptor gamma 3
subunit protein.
Length = 449
Score = 49.2 bits (112), Expect = 2e-05
Identities = 40/156 (25%), Positives = 68/156 (43%), Gaps = 8/156 (5%)
Frame = +3
Query: 114 TSLSLMIDSLLATYDRDSPPDSKI---VVNLTPHLRHANIRESESTMRIQADL--QMNWI 278
T ++L+++ LL YD+ PD I V+++ ++ S M Q D+ W
Sbjct: 27 TDVTLILNKLLREYDKKLRPDIGIKPTVIDVDIYVNSIG-PVSSINMEYQIDIFFAQTWT 85
Query: 279 DKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIK 449
D RL +N+ + +W PD + N+ A R+ N+G + +
Sbjct: 86 DSRLRFNSTMKILTLNSNMVGLIWIPDTIFRNSKTAEAHWITTPNQLLRIWNDGKILYTL 145
Query: 450 RLDISTPISMQLDNWPNDMQTCTFKFGSRMHNXDEM 557
RL I+ +QL N+P D +C F S + +EM
Sbjct: 146 RLTINAECQLQLHNFPMDEHSCPLIFSSYGYPKEEM 181
>S81944-1|AAB36480.1| 453|Homo sapiens gamma-aminobutyric acid type
A receptor alpha 6 subunit protein.
Length = 453
Score = 48.8 bits (111), Expect = 2e-05
Identities = 37/154 (24%), Positives = 65/154 (42%), Gaps = 7/154 (4%)
Frame = +3
Query: 117 SLSLMIDSLLATYD-RDSPPDSKIVVNLTPHLRHAN---IRESESTMRIQADLQMNWIDK 284
++S ++D+LL YD R P V + + + + + E + + W D+
Sbjct: 31 NVSRILDNLLEGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTDE 90
Query: 285 RLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRA---RVSNNGSVSWIKRL 455
RL + S + ++W PD N + A + R+ NG++ + RL
Sbjct: 91 RLKFGGPTEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTMRL 150
Query: 456 DISTPISMQLDNWPNDMQTCTFKFGSRMHNXDEM 557
I+ M+L N+P D C KFGS + E+
Sbjct: 151 TINADCPMRLVNFPMDGHACPLKFGSYAYPKSEI 184
>S62908-1|AAB27279.1| 492|Homo sapiens gamma-aminobutyric acidA
receptor alpha 3 subunit protein.
Length = 492
Score = 48.8 bits (111), Expect = 2e-05
Identities = 36/158 (22%), Positives = 68/158 (43%), Gaps = 7/158 (4%)
Frame = +3
Query: 105 ENATSLSLMIDSLLATYDRDSPP---DSKIVVNLTPHLRHAN-IRESESTMRIQADLQMN 272
+N T + ++D LL YD P D+ V ++ + +++ I +
Sbjct: 62 DNITIFTRILDRLLDGYDNRLRPGLGDAVTEVKTDIYVTSFGPVSDTDMEYTIDVFFRQT 121
Query: 273 WIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSW 443
W D+RL ++ + + ++W PD N + A + R+ +NG++ +
Sbjct: 122 WHDERLKFDGPMKILPLNNLLASKIWTPDTFFHNGKKSVAHNMTTPNKLLRLVDNGTLLY 181
Query: 444 IKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNXDEM 557
RL I M L+++P D+ C KFGS + E+
Sbjct: 182 TMRLTIHAECPMHLEDFPMDVHACPLKFGSYAYTTAEV 219
>BC111802-1|AAI11803.1| 465|Homo sapiens CHRNG protein protein.
Length = 465
Score = 48.8 bits (111), Expect = 2e-05
Identities = 32/113 (28%), Positives = 54/113 (47%), Gaps = 7/113 (6%)
Frame = +3
Query: 129 MIDSLLATYDRDSPPDSKI--VVNLTPHLRHANI---RESESTMRIQADLQMNWIDKRLS 293
++ L+ YD + P + VVN++ L N+ E E + ++M W D RL
Sbjct: 29 LLADLMQNYDPNLRPAERDSDVVNVSLKLTLTNLISLNEREEALTTNVWIEMQWCDYRLR 88
Query: 294 WNAGEW-GCSTWLVSSERLWRPDVVLLNAAAT-TAGDYALRARVSNNGSVSWI 446
W+ ++ G V S +WRPD+VL N + T + + L+ + S+ WI
Sbjct: 89 WDPRDYEGLWVLRVPSTMVWRPDIVLENKSQTYSTNEIDLQLSQEDGQSIEWI 141
>BC099641-1|AAH99641.1| 453|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 6 protein.
Length = 453
Score = 48.8 bits (111), Expect = 2e-05
Identities = 37/154 (24%), Positives = 65/154 (42%), Gaps = 7/154 (4%)
Frame = +3
Query: 117 SLSLMIDSLLATYD-RDSPPDSKIVVNLTPHLRHAN---IRESESTMRIQADLQMNWIDK 284
++S ++D+LL YD R P V + + + + + E + + W D+
Sbjct: 31 NVSRILDNLLEGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTDE 90
Query: 285 RLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRA---RVSNNGSVSWIKRL 455
RL + S + ++W PD N + A + R+ NG++ + RL
Sbjct: 91 RLKFGGPTEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTMRL 150
Query: 456 DISTPISMQLDNWPNDMQTCTFKFGSRMHNXDEM 557
I+ M+L N+P D C KFGS + E+
Sbjct: 151 TINADCPMRLVNFPMDGHACPLKFGSYAYPKSEI 184
>BC099640-1|AAH99640.1| 453|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 6 protein.
Length = 453
Score = 48.8 bits (111), Expect = 2e-05
Identities = 37/154 (24%), Positives = 65/154 (42%), Gaps = 7/154 (4%)
Frame = +3
Query: 117 SLSLMIDSLLATYD-RDSPPDSKIVVNLTPHLRHAN---IRESESTMRIQADLQMNWIDK 284
++S ++D+LL YD R P V + + + + + E + + W D+
Sbjct: 31 NVSRILDNLLEGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTDE 90
Query: 285 RLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRA---RVSNNGSVSWIKRL 455
RL + S + ++W PD N + A + R+ NG++ + RL
Sbjct: 91 RLKFGGPTEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTMRL 150
Query: 456 DISTPISMQLDNWPNDMQTCTFKFGSRMHNXDEM 557
I+ M+L N+P D C KFGS + E+
Sbjct: 151 TINADCPMRLVNFPMDGHACPLKFGSYAYPKSEI 184
>BC096242-1|AAH96242.1| 453|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 6 protein.
Length = 453
Score = 48.8 bits (111), Expect = 2e-05
Identities = 37/154 (24%), Positives = 65/154 (42%), Gaps = 7/154 (4%)
Frame = +3
Query: 117 SLSLMIDSLLATYD-RDSPPDSKIVVNLTPHLRHAN---IRESESTMRIQADLQMNWIDK 284
++S ++D+LL YD R P V + + + + + E + + W D+
Sbjct: 31 NVSRILDNLLEGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTDE 90
Query: 285 RLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRA---RVSNNGSVSWIKRL 455
RL + S + ++W PD N + A + R+ NG++ + RL
Sbjct: 91 RLKFGGPTEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTMRL 150
Query: 456 DISTPISMQLDNWPNDMQTCTFKFGSRMHNXDEM 557
I+ M+L N+P D C KFGS + E+
Sbjct: 151 TINADCPMRLVNFPMDGHACPLKFGSYAYPKSEI 184
>BC096241-1|AAH96241.1| 453|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 6 protein.
Length = 453
Score = 48.8 bits (111), Expect = 2e-05
Identities = 37/154 (24%), Positives = 65/154 (42%), Gaps = 7/154 (4%)
Frame = +3
Query: 117 SLSLMIDSLLATYD-RDSPPDSKIVVNLTPHLRHAN---IRESESTMRIQADLQMNWIDK 284
++S ++D+LL YD R P V + + + + + E + + W D+
Sbjct: 31 NVSRILDNLLEGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTDE 90
Query: 285 RLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRA---RVSNNGSVSWIKRL 455
RL + S + ++W PD N + A + R+ NG++ + RL
Sbjct: 91 RLKFGGPTEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTMRL 150
Query: 456 DISTPISMQLDNWPNDMQTCTFKFGSRMHNXDEM 557
I+ M+L N+P D C KFGS + E+
Sbjct: 151 TINADCPMRLVNFPMDGHACPLKFGSYAYPKSEI 184
>AJ003080-1|CAA05853.1| 238|Homo sapiens serotonin receptor
protein.
Length = 238
Score = 48.8 bits (111), Expect = 2e-05
Identities = 26/109 (23%), Positives = 48/109 (44%), Gaps = 1/109 (0%)
Frame = +3
Query: 219 NIRESESTMRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAG 395
N+ E + + W D+ L WN ++ T L + ++ +W PD+++
Sbjct: 72 NVDEKNQVLTTYIWYRQYWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKS 131
Query: 396 DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMH 542
+ + G V K L + T S+ + N+P D+Q C+ F S +H
Sbjct: 132 PNIPYVYIRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLH 180
>AF166361-1|AAG12455.1| 492|Homo sapiens GABA receptor subunit
alpha 3 protein.
Length = 492
Score = 48.8 bits (111), Expect = 2e-05
Identities = 36/158 (22%), Positives = 68/158 (43%), Gaps = 7/158 (4%)
Frame = +3
Query: 105 ENATSLSLMIDSLLATYDRDSPP---DSKIVVNLTPHLRHAN-IRESESTMRIQADLQMN 272
+N T + ++D LL YD P D+ V ++ + +++ I +
Sbjct: 62 DNITIFTRILDRLLDGYDNRLRPGLGDAVTEVKTDIYVTSFGPVSDTDMEYTIDVFFRQT 121
Query: 273 WIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSW 443
W D+RL ++ + + ++W PD N + A + R+ +NG++ +
Sbjct: 122 WHDERLKFDGPMKILPLNNLLASKIWTPDTFFHNGKKSVAHNMTTPNKLLRLVDNGTLLY 181
Query: 444 IKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNXDEM 557
RL I M L+++P D+ C KFGS + E+
Sbjct: 182 TMRLTIHAECPMHLEDFPMDVHACPLKFGSYAYTTAEV 219
>U77731-2|AAB38273.1| 360|Homo sapiens glycine receptor alpha 2B
subunit protein.
Length = 360
Score = 48.4 bits (110), Expect = 3e-05
Identities = 31/109 (28%), Positives = 49/109 (44%), Gaps = 4/109 (3%)
Frame = +3
Query: 219 NIRESESTMRIQADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERLWRPDVVLLNAAATTAG 395
+I E+ R+ L+ W D RL+++ S + +W+PD+ N
Sbjct: 84 SIAETTMDYRVNIFLRQQWNDSRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFH 143
Query: 396 DYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 533
D R+S NG V + RL ++ M L N+P D+QTCT + S
Sbjct: 144 DVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNFPMDVQTCTMQLES 192
>CR450343-1|CAG29339.1| 452|Homo sapiens GLRA2 protein.
Length = 452
Score = 48.4 bits (110), Expect = 3e-05
Identities = 31/109 (28%), Positives = 49/109 (44%), Gaps = 4/109 (3%)
Frame = +3
Query: 219 NIRESESTMRIQADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERLWRPDVVLLNAAATTAG 395
+I E+ R+ L+ W D RL+++ S + +W+PD+ N
Sbjct: 84 SIAETTMDYRVNIFLRQQWNDSRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFH 143
Query: 396 DYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 533
D R+S NG V + RL ++ M L N+P D+QTCT + S
Sbjct: 144 DVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNFPMDVQTCTMQLES 192
>AY437084-1|AAR87843.1| 452|Homo sapiens glycine receptor alpha2
subunit B protein.
Length = 452
Score = 48.4 bits (110), Expect = 3e-05
Identities = 31/109 (28%), Positives = 49/109 (44%), Gaps = 4/109 (3%)
Frame = +3
Query: 219 NIRESESTMRIQADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERLWRPDVVLLNAAATTAG 395
+I E+ R+ L+ W D RL+++ S + +W+PD+ N
Sbjct: 84 SIAETTMDYRVNIFLRQQWNDSRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFH 143
Query: 396 DYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 533
D R+S NG V + RL ++ M L N+P D+QTCT + S
Sbjct: 144 DVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNFPMDVQTCTMQLES 192
>X52008-1|CAA36257.1| 452|Homo sapiens inhibitory glycine receptor
protein.
Length = 452
Score = 48.0 bits (109), Expect = 4e-05
Identities = 30/109 (27%), Positives = 49/109 (44%), Gaps = 4/109 (3%)
Frame = +3
Query: 219 NIRESESTMRIQADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERLWRPDVVLLNAAATTAG 395
++ E+ R+ L+ W D RL+++ S + +W+PD+ N
Sbjct: 84 SVTETTMDYRVNIFLRQQWNDSRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFH 143
Query: 396 DYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 533
D R+S NG V + RL ++ M L N+P D+QTCT + S
Sbjct: 144 DVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNFPMDVQTCTMQLES 192
>U77731-1|AAB38272.1| 360|Homo sapiens glycine receptor alpha 2
subunit protein.
Length = 360
Score = 48.0 bits (109), Expect = 4e-05
Identities = 30/109 (27%), Positives = 49/109 (44%), Gaps = 4/109 (3%)
Frame = +3
Query: 219 NIRESESTMRIQADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERLWRPDVVLLNAAATTAG 395
++ E+ R+ L+ W D RL+++ S + +W+PD+ N
Sbjct: 84 SVTETTMDYRVNIFLRQQWNDSRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFH 143
Query: 396 DYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 533
D R+S NG V + RL ++ M L N+P D+QTCT + S
Sbjct: 144 DVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNFPMDVQTCTMQLES 192
>U30461-1|AAB52519.1| 554|Homo sapiens GABAA receptor subunit
alpha4 protein.
Length = 554
Score = 48.0 bits (109), Expect = 4e-05
Identities = 32/113 (28%), Positives = 50/113 (44%), Gaps = 3/113 (2%)
Frame = +3
Query: 228 ESESTMRIQADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYAL 407
E E TM + + WIDKRL ++ + ++W PD N + + +
Sbjct: 90 EMEYTMDVF--FRQTWIDKRLKYDGPIEILRLNNMMVTKVWTPDTFFRNGKKSVSHNMTA 147
Query: 408 RA---RVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNXDEM 557
R+ NG++ + RL IS M+L ++P D C KFGS + EM
Sbjct: 148 PNKLFRIMRNGTILYTMRLTISAECPMRLVDFPMDGHACPLKFGSYAYPKSEM 200
>BC035055-1|AAH35055.1| 554|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 4 protein.
Length = 554
Score = 48.0 bits (109), Expect = 4e-05
Identities = 32/113 (28%), Positives = 50/113 (44%), Gaps = 3/113 (2%)
Frame = +3
Query: 228 ESESTMRIQADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYAL 407
E E TM + + WIDKRL ++ + ++W PD N + + +
Sbjct: 90 EMEYTMDVF--FRQTWIDKRLKYDGPIEILRLNNMMVTKVWTPDTFFRNGKKSVSHNMTA 147
Query: 408 RA---RVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNXDEM 557
R+ NG++ + RL IS M+L ++P D C KFGS + EM
Sbjct: 148 PNKLFRIMRNGTILYTMRLTISAECPMRLVDFPMDGHACPLKFGSYAYPKSEM 200
>BC032864-1|AAH32864.1| 452|Homo sapiens glycine receptor, alpha 2
protein.
Length = 452
Score = 48.0 bits (109), Expect = 4e-05
Identities = 30/109 (27%), Positives = 49/109 (44%), Gaps = 4/109 (3%)
Frame = +3
Query: 219 NIRESESTMRIQADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERLWRPDVVLLNAAATTAG 395
++ E+ R+ L+ W D RL+++ S + +W+PD+ N
Sbjct: 84 SVTETTMDYRVNIFLRQQWNDSRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFH 143
Query: 396 DYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 533
D R+S NG V + RL ++ M L N+P D+QTCT + S
Sbjct: 144 DVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNFPMDVQTCTMQLES 192
>AY437083-1|AAR87842.1| 452|Homo sapiens glycine receptor alpha2
subunit A protein.
Length = 452
Score = 48.0 bits (109), Expect = 4e-05
Identities = 30/109 (27%), Positives = 49/109 (44%), Gaps = 4/109 (3%)
Frame = +3
Query: 219 NIRESESTMRIQADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERLWRPDVVLLNAAATTAG 395
++ E+ R+ L+ W D RL+++ S + +W+PD+ N
Sbjct: 84 SVTETTMDYRVNIFLRQQWNDSRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFH 143
Query: 396 DYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 533
D R+S NG V + RL ++ M L N+P D+QTCT + S
Sbjct: 144 DVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNFPMDVQTCTMQLES 192
>AF053495-1|AAC35290.1| 452|Homo sapiens glycine receptor alpha 2
subunit protein.
Length = 452
Score = 48.0 bits (109), Expect = 4e-05
Identities = 30/109 (27%), Positives = 49/109 (44%), Gaps = 4/109 (3%)
Frame = +3
Query: 219 NIRESESTMRIQADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERLWRPDVVLLNAAATTAG 395
++ E+ R+ L+ W D RL+++ S + +W+PD+ N
Sbjct: 84 SVTETTMDYRVNIFLRQQWNDSRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFH 143
Query: 396 DYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 533
D R+S NG V + RL ++ M L N+P D+QTCT + S
Sbjct: 144 DVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNFPMDVQTCTMQLES 192
>M59216-1|AAA35862.1| 474|Homo sapiens gamma-aminobutyric acid
receptor beta-1 subunit protein.
Length = 474
Score = 47.2 bits (107), Expect = 7e-05
Identities = 43/168 (25%), Positives = 73/168 (43%), Gaps = 7/168 (4%)
Frame = +3
Query: 78 CAIASAAECENATSLSLMIDSLLATYDRDSPPD-SKIVVNLTPHLRHANI-RESESTMRI 251
C S E N + + +D LL YD PD V++ + A+I SE M
Sbjct: 23 CCAHSTNEPSNMSYVKETVDRLLKGYDIRLRPDFGGPPVDVGMRIDVASIDMVSEVNMDY 82
Query: 252 QADL--QMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---AR 416
+ Q +W DKRLS++ + +++LW PD LN + ++ R
Sbjct: 83 TLTMYFQQSWKDKRLSYSGIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIR 142
Query: 417 VSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNXDEMD 560
+ +G+V + R+ + M L +P D Q CT + S + D+++
Sbjct: 143 LHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIE 190
>X14767-1|CAA32875.1| 474|Homo sapiens GABA-A receptor beta 1
subunit protein.
Length = 474
Score = 46.4 bits (105), Expect = 1e-04
Identities = 43/168 (25%), Positives = 72/168 (42%), Gaps = 7/168 (4%)
Frame = +3
Query: 78 CAIASAAECENATSLSLMIDSLLATYDRDSPPD-SKIVVNLTPHLRHANI-RESESTMRI 251
C S E N + +D LL YD PD V++ + A+I SE M
Sbjct: 23 CCAHSTNEPSNMPYVKETVDRLLKGYDIRLRPDFGGPPVDVGMRIDVASIDMVSEVNMDY 82
Query: 252 QADL--QMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---AR 416
+ Q +W DKRLS++ + +++LW PD LN + ++ R
Sbjct: 83 TLTMYFQQSWKDKRLSYSGIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIR 142
Query: 417 VSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNXDEMD 560
+ +G+V + R+ + M L +P D Q CT + S + D+++
Sbjct: 143 LHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIE 190
>S77554-1|AAB33983.1| 474|Homo sapiens GABAA receptor beta 2
subunit protein.
Length = 474
Score = 46.4 bits (105), Expect = 1e-04
Identities = 40/168 (23%), Positives = 70/168 (41%), Gaps = 7/168 (4%)
Frame = +3
Query: 78 CAIASAAECENATSLSLMIDSLLATYDRDSPPD---SKIVVNLTPHLRHAN-IRESESTM 245
CA S + N + + +D LL YD PD + V + + + + E
Sbjct: 23 CA-QSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDIASIDMVSEVNMDY 81
Query: 246 RIQADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---AR 416
+ Q W DKRLS+N + +++LW PD LN + ++ R
Sbjct: 82 TLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIR 141
Query: 417 VSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNXDEMD 560
+ +G+V + R+ + M L +P D Q CT + S + D+++
Sbjct: 142 LHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIE 189
>S77553-1|AAB33982.1| 512|Homo sapiens GABAA receptor beta 2
subunit protein.
Length = 512
Score = 46.4 bits (105), Expect = 1e-04
Identities = 40/168 (23%), Positives = 70/168 (41%), Gaps = 7/168 (4%)
Frame = +3
Query: 78 CAIASAAECENATSLSLMIDSLLATYDRDSPPD---SKIVVNLTPHLRHAN-IRESESTM 245
CA S + N + + +D LL YD PD + V + + + + E
Sbjct: 23 CA-QSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDIASIDMVSEVNMDY 81
Query: 246 RIQADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---AR 416
+ Q W DKRLS+N + +++LW PD LN + ++ R
Sbjct: 82 TLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIR 141
Query: 417 VSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNXDEMD 560
+ +G+V + R+ + M L +P D Q CT + S + D+++
Sbjct: 142 LHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIE 189
>S67368-1|AAB29370.1| 474|Homo sapiens gamma-aminobutyric acid A
receptor beta 2 subunit protein.
Length = 474
Score = 46.4 bits (105), Expect = 1e-04
Identities = 40/168 (23%), Positives = 70/168 (41%), Gaps = 7/168 (4%)
Frame = +3
Query: 78 CAIASAAECENATSLSLMIDSLLATYDRDSPPD---SKIVVNLTPHLRHAN-IRESESTM 245
CA S + N + + +D LL YD PD + V + + + + E
Sbjct: 23 CA-QSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDIASIDMVSEVNMDY 81
Query: 246 RIQADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---AR 416
+ Q W DKRLS+N + +++LW PD LN + ++ R
Sbjct: 82 TLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIR 141
Query: 417 VSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNXDEMD 560
+ +G+V + R+ + M L +P D Q CT + S + D+++
Sbjct: 142 LHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIE 189
>BC105639-1|AAI05640.1| 474|Homo sapiens GABRB2 protein protein.
Length = 474
Score = 46.4 bits (105), Expect = 1e-04
Identities = 40/168 (23%), Positives = 70/168 (41%), Gaps = 7/168 (4%)
Frame = +3
Query: 78 CAIASAAECENATSLSLMIDSLLATYDRDSPPD---SKIVVNLTPHLRHAN-IRESESTM 245
CA S + N + + +D LL YD PD + V + + + + E
Sbjct: 23 CA-QSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDIASIDMVSEVNMDY 81
Query: 246 RIQADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---AR 416
+ Q W DKRLS+N + +++LW PD LN + ++ R
Sbjct: 82 TLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIR 141
Query: 417 VSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNXDEMD 560
+ +G+V + R+ + M L +P D Q CT + S + D+++
Sbjct: 142 LHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIE 189
>BC099719-1|AAH99719.1| 474|Homo sapiens GABRB2 protein protein.
Length = 474
Score = 46.4 bits (105), Expect = 1e-04
Identities = 40/168 (23%), Positives = 70/168 (41%), Gaps = 7/168 (4%)
Frame = +3
Query: 78 CAIASAAECENATSLSLMIDSLLATYDRDSPPD---SKIVVNLTPHLRHAN-IRESESTM 245
CA S + N + + +D LL YD PD + V + + + + E
Sbjct: 23 CA-QSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDIASIDMVSEVNMDY 81
Query: 246 RIQADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---AR 416
+ Q W DKRLS+N + +++LW PD LN + ++ R
Sbjct: 82 TLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIR 141
Query: 417 VSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNXDEMD 560
+ +G+V + R+ + M L +P D Q CT + S + D+++
Sbjct: 142 LHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIE 189
>BC099705-1|AAH99705.1| 474|Homo sapiens GABRB2 protein protein.
Length = 474
Score = 46.4 bits (105), Expect = 1e-04
Identities = 40/168 (23%), Positives = 70/168 (41%), Gaps = 7/168 (4%)
Frame = +3
Query: 78 CAIASAAECENATSLSLMIDSLLATYDRDSPPD---SKIVVNLTPHLRHAN-IRESESTM 245
CA S + N + + +D LL YD PD + V + + + + E
Sbjct: 23 CA-QSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDIASIDMVSEVNMDY 81
Query: 246 RIQADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---AR 416
+ Q W DKRLS+N + +++LW PD LN + ++ R
Sbjct: 82 TLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIR 141
Query: 417 VSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNXDEMD 560
+ +G+V + R+ + M L +P D Q CT + S + D+++
Sbjct: 142 LHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIE 189
>BC096083-1|AAH96083.1| 198|Homo sapiens CHRNB4 protein protein.
Length = 198
Score = 46.4 bits (105), Expect = 1e-04
Identities = 30/115 (26%), Positives = 54/115 (46%), Gaps = 8/115 (6%)
Frame = +3
Query: 81 AIASAAECENATSLSLMIDSLL--ATYD---RDSPPDSKIV-VNLTPHLRHA-NIRESES 239
A+ C A + ++D LL Y+ R + S+++ + L L ++ E E
Sbjct: 14 ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQ 73
Query: 240 TMRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDY 401
M L+ W D RL+WN+ + G + + ++R+W PD+VL N + T +
Sbjct: 74 IMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNKSLRTGSTW 128
>BC096081-1|AAH96081.1| 198|Homo sapiens CHRNB4 protein protein.
Length = 198
Score = 46.4 bits (105), Expect = 1e-04
Identities = 30/115 (26%), Positives = 54/115 (46%), Gaps = 8/115 (6%)
Frame = +3
Query: 81 AIASAAECENATSLSLMIDSLL--ATYD---RDSPPDSKIV-VNLTPHLRHA-NIRESES 239
A+ C A + ++D LL Y+ R + S+++ + L L ++ E E
Sbjct: 14 ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQ 73
Query: 240 TMRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDY 401
M L+ W D RL+WN+ + G + + ++R+W PD+VL N + T +
Sbjct: 74 IMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNKSLRTGSTW 128
>X52009-1|CAA36258.1| 449|Homo sapiens inhibitory glycine receptor
protein.
Length = 449
Score = 44.8 bits (101), Expect = 4e-04
Identities = 29/109 (26%), Positives = 49/109 (44%), Gaps = 4/109 (3%)
Frame = +3
Query: 219 NIRESESTMRIQADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERLWRPDVVLLNAAATTAG 395
+I E+ R+ L+ W D RL++N S + +W+PD+ N
Sbjct: 78 SIAETTMDYRVNIFLRQQWNDPRLAYNEYPDDSLDLDPSMLDSIWKPDLFFANEKGAHFH 137
Query: 396 DYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 533
+ R+S NG+V + R+ ++ M L N+P D+QTC + S
Sbjct: 138 EITTDNKLLRISRNGNVLYSIRITLTLACPMDLKNFPMDVQTCIMQLES 186
>BC114947-1|AAI14948.1| 457|Homo sapiens GLRA1 protein protein.
Length = 457
Score = 44.8 bits (101), Expect = 4e-04
Identities = 29/109 (26%), Positives = 49/109 (44%), Gaps = 4/109 (3%)
Frame = +3
Query: 219 NIRESESTMRIQADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERLWRPDVVLLNAAATTAG 395
+I E+ R+ L+ W D RL++N S + +W+PD+ N
Sbjct: 78 SIAETTMDYRVNIFLRQQWNDPRLAYNEYPDDSLDLDPSMLDSIWKPDLFFANEKGAHFH 137
Query: 396 DYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 533
+ R+S NG+V + R+ ++ M L N+P D+QTC + S
Sbjct: 138 EITTDNKLLRISRNGNVLYSIRITLTLACPMDLKNFPMDVQTCIMQLES 186
>BC074980-1|AAH74980.1| 449|Homo sapiens glycine receptor, alpha 1
(startle disease/hyperekplexia) protein.
Length = 449
Score = 44.8 bits (101), Expect = 4e-04
Identities = 29/109 (26%), Positives = 49/109 (44%), Gaps = 4/109 (3%)
Frame = +3
Query: 219 NIRESESTMRIQADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERLWRPDVVLLNAAATTAG 395
+I E+ R+ L+ W D RL++N S + +W+PD+ N
Sbjct: 78 SIAETTMDYRVNIFLRQQWNDPRLAYNEYPDDSLDLDPSMLDSIWKPDLFFANEKGAHFH 137
Query: 396 DYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 533
+ R+S NG+V + R+ ++ M L N+P D+QTC + S
Sbjct: 138 EITTDNKLLRISRNGNVLYSIRITLTLACPMDLKNFPMDVQTCIMQLES 186
>BC109211-1|AAI09212.1| 632|Homo sapiens gamma-aminobutyric acid
(GABA) receptor, theta protein.
Length = 632
Score = 44.0 bits (99), Expect = 7e-04
Identities = 35/145 (24%), Positives = 59/145 (40%), Gaps = 7/145 (4%)
Frame = +3
Query: 102 CENATSLSLMIDSLLATYDRDSPPD---SKIVVNLTPHLRHAN-IRESESTMRIQADLQM 269
C N + ++D +L+ YD P+ + + V ++ ++ I E I
Sbjct: 53 CANEAVVQKILDRVLSRYDVRLRPNFGGAPVPVRISIYVTSIEQISEMNMDYTITMFFHQ 112
Query: 270 NWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSN---NGSVS 440
W D RL++ + E+LW PD LN+ D + RV +G+V
Sbjct: 113 TWKDSRLAYYETTLNLTLDYRMHEKLWVPDCYFLNSKDAFVHDVTVENRVFQLHPDGTVR 172
Query: 441 WIKRLDISTPISMQLDNWPNDMQTC 515
+ RL + S+ L +P D Q C
Sbjct: 173 YGIRLTTTAACSLDLHKFPMDKQAC 197
>BC109210-1|AAI09211.1| 632|Homo sapiens gamma-aminobutyric acid
(GABA) receptor, theta protein.
Length = 632
Score = 44.0 bits (99), Expect = 7e-04
Identities = 35/145 (24%), Positives = 59/145 (40%), Gaps = 7/145 (4%)
Frame = +3
Query: 102 CENATSLSLMIDSLLATYDRDSPPD---SKIVVNLTPHLRHAN-IRESESTMRIQADLQM 269
C N + ++D +L+ YD P+ + + V ++ ++ I E I
Sbjct: 53 CANEAVVQKILDRVLSRYDVRLRPNFGGAPVPVRISIYVTSIEQISEMNMDYTITMFFHQ 112
Query: 270 NWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSN---NGSVS 440
W D RL++ + E+LW PD LN+ D + RV +G+V
Sbjct: 113 TWKDSRLAYYETTLNLTLDYRMHEKLWVPDCYFLNSKDAFVHDVTVENRVFQLHPDGTVR 172
Query: 441 WIKRLDISTPISMQLDNWPNDMQTC 515
+ RL + S+ L +P D Q C
Sbjct: 173 YGIRLTTTAACSLDLHKFPMDKQAC 197
>AF189259-1|AAF70380.1| 632|Homo sapiens GABA-A receptor theta
subunit protein.
Length = 632
Score = 44.0 bits (99), Expect = 7e-04
Identities = 35/145 (24%), Positives = 59/145 (40%), Gaps = 7/145 (4%)
Frame = +3
Query: 102 CENATSLSLMIDSLLATYDRDSPPD---SKIVVNLTPHLRHAN-IRESESTMRIQADLQM 269
C N + ++D +L+ YD P+ + + V ++ ++ I E I
Sbjct: 53 CANEAVVQKILDRVLSRYDVRLRPNFGGAPVPVRISIYVTSIEQISEMNMDYTITMFFHQ 112
Query: 270 NWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSN---NGSVS 440
W D RL++ + E+LW PD LN+ D + RV +G+V
Sbjct: 113 TWKDSRLAYYETTLNLTLDYRMHEKLWVPDCYFLNSKDAFVHDVTVENRVFQLHPDGTVR 172
Query: 441 WIKRLDISTPISMQLDNWPNDMQTC 515
+ RL + S+ L +P D Q C
Sbjct: 173 YGIRLTTTAACSLDLHKFPMDKQAC 197
>AF144648-1|AAD51172.1| 627|Homo sapiens GABA-A receptor theta
protein.
Length = 627
Score = 44.0 bits (99), Expect = 7e-04
Identities = 35/145 (24%), Positives = 59/145 (40%), Gaps = 7/145 (4%)
Frame = +3
Query: 102 CENATSLSLMIDSLLATYDRDSPPD---SKIVVNLTPHLRHAN-IRESESTMRIQADLQM 269
C N + ++D +L+ YD P+ + + V ++ ++ I E I
Sbjct: 48 CANEAVVQKILDRVLSRYDVRLRPNFGGAPVPVRISIYVTSIEQISEMNMDYTITMFFHQ 107
Query: 270 NWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSN---NGSVS 440
W D RL++ + E+LW PD LN+ D + RV +G+V
Sbjct: 108 TWKDSRLAYYETTLNLTLDYRMHEKLWVPDCYFLNSKDAFVHDVTVENRVFQLHPDGTVR 167
Query: 441 WIKRLDISTPISMQLDNWPNDMQTC 515
+ RL + S+ L +P D Q C
Sbjct: 168 YGIRLTTTAACSLDLHKFPMDKQAC 192
>BC033801-1|AAH33801.1| 452|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, delta protein.
Length = 452
Score = 43.6 bits (98), Expect = 9e-04
Identities = 38/149 (25%), Positives = 65/149 (43%), Gaps = 7/149 (4%)
Frame = +3
Query: 132 IDSLLATYDRDSPPD-SKIVVNLTPHLRHANIRE-SESTMR--IQADLQMNWIDKRLSWN 299
+D L+A Y R+ P VN+ L A+I SE+ M + L +W D RLS+N
Sbjct: 44 LDGLIAGYARNFRPGIGGPPVNVALALEVASIDHISEANMEYTMTVFLHQSWRDSRLSYN 103
Query: 300 AGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTP 470
++LW PD ++NA + D + R+ +G + + R+ +
Sbjct: 104 HTNETLGLDSRFVDKLWLPDTFIVNAKSAWFHDVTVENKLIRLQPDGVILYSIRITSTVA 163
Query: 471 ISMQLDNWPNDMQTCTFKFGSRMHNXDEM 557
M L +P D Q C S ++ +++
Sbjct: 164 CDMDLAKYPMDEQECMLDLESYGYSSEDI 192
>AL391845-4|CAI15436.1| 452|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, delta protein.
Length = 452
Score = 43.6 bits (98), Expect = 9e-04
Identities = 38/149 (25%), Positives = 65/149 (43%), Gaps = 7/149 (4%)
Frame = +3
Query: 132 IDSLLATYDRDSPPD-SKIVVNLTPHLRHANIRE-SESTMR--IQADLQMNWIDKRLSWN 299
+D L+A Y R+ P VN+ L A+I SE+ M + L +W D RLS+N
Sbjct: 44 LDGLIAGYARNFRPGIGGPPVNVALALEVASIDHISEANMEYTMTVFLHQSWRDSRLSYN 103
Query: 300 AGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTP 470
++LW PD ++NA + D + R+ +G + + R+ +
Sbjct: 104 HTNETLGLDSRFVDKLWLPDTFIVNAKSAWFHDVTVENKLIRLQPDGVILYSIRITSTVA 163
Query: 471 ISMQLDNWPNDMQTCTFKFGSRMHNXDEM 557
M L +P D Q C S ++ +++
Sbjct: 164 CDMDLAKYPMDEQECMLDLESYGYSSEDI 192
>AF016917-1|AAB70007.1| 452|Homo sapiens GABA-A receptor delta
subunit protein.
Length = 452
Score = 43.6 bits (98), Expect = 9e-04
Identities = 38/149 (25%), Positives = 65/149 (43%), Gaps = 7/149 (4%)
Frame = +3
Query: 132 IDSLLATYDRDSPPD-SKIVVNLTPHLRHANIRE-SESTMR--IQADLQMNWIDKRLSWN 299
+D L+A Y R+ P VN+ L A+I SE+ M + L +W D RLS+N
Sbjct: 44 LDGLIAGYARNFRPGIGGPPVNVALALEVASIDHISEANMEYTMTVFLHQSWRDSRLSYN 103
Query: 300 AGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTP 470
++LW PD ++NA + D + R+ +G + + R+ +
Sbjct: 104 HTNETLGLDSRFVDKLWLPDTFIVNAKSAWFHDVTVENKLIRLQPDGVILYSIRITSTVA 163
Query: 471 ISMQLDNWPNDMQTCTFKFGSRMHNXDEM 557
M L +P D Q C S ++ +++
Sbjct: 164 CDMDLAKYPMDEQECMLDLESYGYSSEDI 192
>BC074795-1|AAH74795.1| 467|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, gamma 2 protein.
Length = 467
Score = 43.2 bits (97), Expect = 0.001
Identities = 34/153 (22%), Positives = 65/153 (42%), Gaps = 7/153 (4%)
Frame = +3
Query: 120 LSLMIDSLLATYDRDSPPDSKIVVNLTPHLRHANIRESESTMRIQADLQM----NWIDKR 287
+++++++LL YD PD + L + N + + ++ + + W D+R
Sbjct: 66 VTVILNNLLEGYDNKLRPDIGVKPTLIHTDMYVNSIGPVNAINMEYTIDIFFAQTWYDRR 125
Query: 288 LSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYAL---RARVSNNGSVSWIKRLD 458
L +N+ ++W PD N+ A R+ N+G V + RL
Sbjct: 126 LKFNSTIKVLRLNSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYTLRLT 185
Query: 459 ISTPISMQLDNWPNDMQTCTFKFGSRMHNXDEM 557
I +QL N+P D +C +F S + +E+
Sbjct: 186 IDAECQLQLHNFPMDEHSCPLEFSSYGYPREEI 218
>BC069348-1|AAH69348.1| 467|Homo sapiens gamma-aminobutyric acid A
receptor, gamma 2, isoform 2 precursor protein.
Length = 467
Score = 43.2 bits (97), Expect = 0.001
Identities = 34/153 (22%), Positives = 65/153 (42%), Gaps = 7/153 (4%)
Frame = +3
Query: 120 LSLMIDSLLATYDRDSPPDSKIVVNLTPHLRHANIRESESTMRIQADLQM----NWIDKR 287
+++++++LL YD PD + L + N + + ++ + + W D+R
Sbjct: 66 VTVILNNLLEGYDNKLRPDIGVKPTLIHTDMYVNSIGPVNAINMEYTIDIFFAQTWYDRR 125
Query: 288 LSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYAL---RARVSNNGSVSWIKRLD 458
L +N+ ++W PD N+ A R+ N+G V + RL
Sbjct: 126 LKFNSTIKVLRLNSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYTLRLT 185
Query: 459 ISTPISMQLDNWPNDMQTCTFKFGSRMHNXDEM 557
I +QL N+P D +C +F S + +E+
Sbjct: 186 IDAECQLQLHNFPMDEHSCPLEFSSYGYPREEI 218
>BC059389-1|AAH59389.1| 475|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, gamma 2 protein.
Length = 475
Score = 43.2 bits (97), Expect = 0.001
Identities = 34/153 (22%), Positives = 65/153 (42%), Gaps = 7/153 (4%)
Frame = +3
Query: 120 LSLMIDSLLATYDRDSPPDSKIVVNLTPHLRHANIRESESTMRIQADLQM----NWIDKR 287
+++++++LL YD PD + L + N + + ++ + + W D+R
Sbjct: 66 VTVILNNLLEGYDNKLRPDIGVKPTLIHTDMYVNSIGPVNAINMEYTIDIFFAQTWYDRR 125
Query: 288 LSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYAL---RARVSNNGSVSWIKRLD 458
L +N+ ++W PD N+ A R+ N+G V + RL
Sbjct: 126 LKFNSTIKVLRLNSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYTLRLT 185
Query: 459 ISTPISMQLDNWPNDMQTCTFKFGSRMHNXDEM 557
I +QL N+P D +C +F S + +E+
Sbjct: 186 IDAECQLQLHNFPMDEHSCPLEFSSYGYPREEI 218
>AF165124-1|AAD50273.1| 467|Homo sapiens gamma-aminobutyric acid A
receptor gamma 2 protein.
Length = 467
Score = 43.2 bits (97), Expect = 0.001
Identities = 34/153 (22%), Positives = 65/153 (42%), Gaps = 7/153 (4%)
Frame = +3
Query: 120 LSLMIDSLLATYDRDSPPDSKIVVNLTPHLRHANIRESESTMRIQADLQM----NWIDKR 287
+++++++LL YD PD + L + N + + ++ + + W D+R
Sbjct: 66 VTVILNNLLEGYDNKLRPDIGVKPTLIHTDMYVNSIGPVNAINMEYTIDIFFAQTWYDRR 125
Query: 288 LSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYAL---RARVSNNGSVSWIKRLD 458
L +N+ ++W PD N+ A R+ N+G V + RL
Sbjct: 126 LKFNSTIKVLRLNSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYTLRLT 185
Query: 459 ISTPISMQLDNWPNDMQTCTFKFGSRMHNXDEM 557
I +QL N+P D +C +F S + +E+
Sbjct: 186 IDAECQLQLHNFPMDEHSCPLEFSSYGYPREEI 218
>Z93848-1|CAI41994.1| 376|Homo sapiens glycine receptor, alpha 4
protein.
Length = 376
Score = 42.7 bits (96), Expect = 0.002
Identities = 29/110 (26%), Positives = 48/110 (43%), Gaps = 4/110 (3%)
Frame = +3
Query: 216 ANIRESESTMRIQADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERLWRPDVVLLNAAATTA 392
++I ++ R+ L+ W D RLS+ S + +W+PD+ N
Sbjct: 42 SSITKTTMDYRVNVFLRQQWNDPRLSYREYPDDSLDLDPSMLDSIWKPDLFFANEKGANF 101
Query: 393 GDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 533
+ R+ NG+V + RL + M L N+P D+QTCT + S
Sbjct: 102 HEVTTDNKLLRIFKNGNVLYSIRLTLILSCLMDLKNFPMDIQTCTMQLES 151
>AL049610-1|CAI42158.1| 376|Homo sapiens glycine receptor, alpha 4
protein.
Length = 376
Score = 42.7 bits (96), Expect = 0.002
Identities = 29/110 (26%), Positives = 48/110 (43%), Gaps = 4/110 (3%)
Frame = +3
Query: 216 ANIRESESTMRIQADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERLWRPDVVLLNAAATTA 392
++I ++ R+ L+ W D RLS+ S + +W+PD+ N
Sbjct: 42 SSITKTTMDYRVNVFLRQQWNDPRLSYREYPDDSLDLDPSMLDSIWKPDLFFANEKGANF 101
Query: 393 GDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 533
+ R+ NG+V + RL + M L N+P D+QTCT + S
Sbjct: 102 HEVTTDNKLLRIFKNGNVLYSIRLTLILSCLMDLKNFPMDIQTCTMQLES 151
>BC114967-1|AAI14968.1| 366|Homo sapiens GLRA1 protein protein.
Length = 366
Score = 42.3 bits (95), Expect = 0.002
Identities = 27/100 (27%), Positives = 45/100 (45%), Gaps = 4/100 (4%)
Frame = +3
Query: 246 RIQADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERLWRPDVVLLNAAATTAGDYALR---A 413
R+ L+ W D RL++N S + +W+PD+ N +
Sbjct: 4 RVNIFLRQQWNDPRLAYNEYPDDSLDLDPSMLDSIWKPDLFFANEKGAHFHEITTDNKLL 63
Query: 414 RVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 533
R+S NG+V + R+ ++ M L N+P D+QTC + S
Sbjct: 64 RISRNGNVLYSIRITLTLACPMDLKNFPMDVQTCIMQLES 103
>X15376-1|CAA33437.1| 467|Homo sapiens GABA-A receptor gamma 2
subunit protein.
Length = 467
Score = 41.9 bits (94), Expect = 0.003
Identities = 34/153 (22%), Positives = 65/153 (42%), Gaps = 7/153 (4%)
Frame = +3
Query: 120 LSLMIDSLLATYDRDSPPDSKIVVNLTPHLRHANIRESESTMRIQADLQM----NWIDKR 287
+++++++LL YD PD + L + N + + ++ + + W D+R
Sbjct: 66 VTVILNNLLEGYDNKLRPDIGVKPTLIHTDMYVNSIGPVNAINMEYTIDIFFAQMWYDRR 125
Query: 288 LSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYAL---RARVSNNGSVSWIKRLD 458
L +N+ ++W PD N+ A R+ N+G V + RL
Sbjct: 126 LKFNSTIKVLRLNSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYSLRLT 185
Query: 459 ISTPISMQLDNWPNDMQTCTFKFGSRMHNXDEM 557
I +QL N+P D +C +F S + +E+
Sbjct: 186 IDAECQLQLHNFPMDEHSCPLEFSSYGYPREEI 218
>U93917-1|AAC39917.1| 449|Homo sapiens glycine receptor alpha 3
subunit protein.
Length = 449
Score = 41.9 bits (94), Expect = 0.003
Identities = 28/109 (25%), Positives = 48/109 (44%), Gaps = 4/109 (3%)
Frame = +3
Query: 219 NIRESESTMRIQADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERLWRPDVVLLNAAATTAG 395
+I E+ R+ L+ W D RL+++ S + +W+PD+ N
Sbjct: 83 SIAETTMDYRVNIFLRQKWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFH 142
Query: 396 DYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 533
+ R+ NG+V + RL ++ M L N+P D+QTC + S
Sbjct: 143 EVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFPMDVQTCIMQLES 191
>BC036086-1|AAH36086.1| 464|Homo sapiens glycine receptor, alpha 3
protein.
Length = 464
Score = 41.9 bits (94), Expect = 0.003
Identities = 28/109 (25%), Positives = 48/109 (44%), Gaps = 4/109 (3%)
Frame = +3
Query: 219 NIRESESTMRIQADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERLWRPDVVLLNAAATTAG 395
+I E+ R+ L+ W D RL+++ S + +W+PD+ N
Sbjct: 83 SIAETTMDYRVNIFLRQKWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFH 142
Query: 396 DYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 533
+ R+ NG+V + RL ++ M L N+P D+QTC + S
Sbjct: 143 EVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFPMDVQTCIMQLES 191
>BC022449-1|AAH22449.1| 474|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, beta 1 protein.
Length = 474
Score = 41.9 bits (94), Expect = 0.003
Identities = 42/168 (25%), Positives = 72/168 (42%), Gaps = 7/168 (4%)
Frame = +3
Query: 78 CAIASAAECENATSLSLMIDSLLATYDRDSPPD-SKIVVNLTPHLRHANI-RESESTMRI 251
C S E N + + +D LL YD PD V++ + A+I SE M
Sbjct: 23 CCAHSTNEPSNMSYVKETVDRLLKGYDIRLRPDFGGPPVDVGMRIDVASIDMVSEVNMDY 82
Query: 252 QADL--QMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---AR 416
+ Q +W DKRLS++ + +++L PD LN + ++ R
Sbjct: 83 TLTMYFQQSWKDKRLSYSGIPLNLTLDNRVADQLCVPDTYFLNDKKSFVHGVTVKNRMIR 142
Query: 417 VSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNXDEMD 560
+ +G+V + R+ + M L +P D Q CT + S + D+++
Sbjct: 143 LHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIE 190
>AF017724-1|AAC39919.1| 465|Homo sapiens glycine receptor alpha 3
subunit protein.
Length = 465
Score = 41.9 bits (94), Expect = 0.003
Identities = 28/109 (25%), Positives = 48/109 (44%), Gaps = 4/109 (3%)
Frame = +3
Query: 219 NIRESESTMRIQADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERLWRPDVVLLNAAATTAG 395
+I E+ R+ L+ W D RL+++ S + +W+PD+ N
Sbjct: 83 SIAETTMDYRVNIFLRQKWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFH 142
Query: 396 DYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 533
+ R+ NG+V + RL ++ M L N+P D+QTC + S
Sbjct: 143 EVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFPMDVQTCIMQLES 191
>BC031087-1|AAH31087.1| 465|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, gamma 1 protein.
Length = 465
Score = 41.5 bits (93), Expect = 0.004
Identities = 35/154 (22%), Positives = 63/154 (40%), Gaps = 7/154 (4%)
Frame = +3
Query: 120 LSLMIDSLLATYDRDSPPDSKI---VVNLTPHLRHAN-IRESESTMRIQADLQMNWIDKR 287
++ +++SLL YD PD + V+ ++ + I W D R
Sbjct: 64 ITQILNSLLQGYDNKLRPDIGVRPTVIETDVYVNSIGPVDPINMEYTIDIIFAQTWFDSR 123
Query: 288 LSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLD 458
L +N+ ++W PD N+ + A R+ N+G V + RL
Sbjct: 124 LKFNSTMKVLMLNSNMVGKIWIPDTFFRNSRKSDAHWITTPNRLLRIWNDGRVLYTLRLT 183
Query: 459 ISTPISMQLDNWPNDMQTCTFKFGSRMHNXDEMD 560
I+ +QL N+P D +C +F S + +E++
Sbjct: 184 INAECYLQLHNFPMDEHSCPLEFSSYGYPKNEIE 217
>U95367-1|AAC51357.1| 440|Homo sapiens GABA-A receptor pi subunit
protein.
Length = 440
Score = 41.1 bits (92), Expect = 0.005
Identities = 30/116 (25%), Positives = 57/116 (49%), Gaps = 6/116 (5%)
Frame = +3
Query: 231 SESTMRIQAD--LQMNWIDKRLSWNAGE-WGCSTWLVSSERLWRPDVVLLNAAATTAGDY 401
SES M A L+ W+D+RL + + + LV E LW PD ++ + + +
Sbjct: 76 SESNMDYTATIYLRQRWMDQRLVFEGNKSFTLDARLV--EFLWVPDTYIVESKKSFLHEV 133
Query: 402 ALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNXDEMD 560
+ R+ +NG+V + R+ + +M L +P D QTC + S ++ ++++
Sbjct: 134 TVGNRLIRLFSNGTVLYALRITTTVACNMDLSKYPMDTQTCKLQLESWGYDGNDVE 189
>BC109106-1|AAI09107.1| 440|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, pi protein.
Length = 440
Score = 41.1 bits (92), Expect = 0.005
Identities = 30/116 (25%), Positives = 57/116 (49%), Gaps = 6/116 (5%)
Frame = +3
Query: 231 SESTMRIQAD--LQMNWIDKRLSWNAGE-WGCSTWLVSSERLWRPDVVLLNAAATTAGDY 401
SES M A L+ W+D+RL + + + LV E LW PD ++ + + +
Sbjct: 76 SESNMDYTATIYLRQRWMDQRLVFEGNKSFTLDARLV--EFLWVPDTYIVESKKSFLHEV 133
Query: 402 ALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNXDEMD 560
+ R+ +NG+V + R+ + +M L +P D QTC + S ++ ++++
Sbjct: 134 TVGNRLIRLFSNGTVLYALRITTTVACNMDLSKYPMDTQTCKLQLESWGYDGNDVE 189
>BC109105-1|AAI09106.1| 440|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, pi protein.
Length = 440
Score = 41.1 bits (92), Expect = 0.005
Identities = 30/116 (25%), Positives = 57/116 (49%), Gaps = 6/116 (5%)
Frame = +3
Query: 231 SESTMRIQAD--LQMNWIDKRLSWNAGE-WGCSTWLVSSERLWRPDVVLLNAAATTAGDY 401
SES M A L+ W+D+RL + + + LV E LW PD ++ + + +
Sbjct: 76 SESNMDYTATIYLRQRWMDQRLVFEGNKSFTLDARLV--EFLWVPDTYIVESKKSFLHEV 133
Query: 402 ALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNXDEMD 560
+ R+ +NG+V + R+ + +M L +P D QTC + S ++ ++++
Sbjct: 134 TVGNRLIRLFSNGTVLYALRITTTVACNMDLSKYPMDTQTCKLQLESWGYDGNDVE 189
>BC074865-1|AAH74865.1| 440|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, pi protein.
Length = 440
Score = 41.1 bits (92), Expect = 0.005
Identities = 30/116 (25%), Positives = 57/116 (49%), Gaps = 6/116 (5%)
Frame = +3
Query: 231 SESTMRIQAD--LQMNWIDKRLSWNAGE-WGCSTWLVSSERLWRPDVVLLNAAATTAGDY 401
SES M A L+ W+D+RL + + + LV E LW PD ++ + + +
Sbjct: 76 SESNMDYTATIYLRQRWMDQRLVFEGNKSFTLDARLV--EFLWVPDTYIVESKKSFLHEV 133
Query: 402 ALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNXDEMD 560
+ R+ +NG+V + R+ + +M L +P D QTC + S ++ ++++
Sbjct: 134 TVGNRLIRLFSNGTVLYALRITTTVACNMDLSKYPMDTQTCKLQLESWGYDGNDVE 189
>BC074810-1|AAH74810.1| 440|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, pi protein.
Length = 440
Score = 41.1 bits (92), Expect = 0.005
Identities = 30/116 (25%), Positives = 57/116 (49%), Gaps = 6/116 (5%)
Frame = +3
Query: 231 SESTMRIQAD--LQMNWIDKRLSWNAGE-WGCSTWLVSSERLWRPDVVLLNAAATTAGDY 401
SES M A L+ W+D+RL + + + LV E LW PD ++ + + +
Sbjct: 76 SESNMDYTATIYLRQRWMDQRLVFEGNKSFTLDARLV--EFLWVPDTYIVESKKSFLHEV 133
Query: 402 ALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNXDEMD 560
+ R+ +NG+V + R+ + +M L +P D QTC + S ++ ++++
Sbjct: 134 TVGNRLIRLFSNGTVLYALRITTTVACNMDLSKYPMDTQTCKLQLESWGYDGNDVE 189
>AF009702-1|AAC24194.1| 440|Homo sapiens GABA-A receptor pi subunit
protein.
Length = 440
Score = 41.1 bits (92), Expect = 0.005
Identities = 30/116 (25%), Positives = 57/116 (49%), Gaps = 6/116 (5%)
Frame = +3
Query: 231 SESTMRIQAD--LQMNWIDKRLSWNAGE-WGCSTWLVSSERLWRPDVVLLNAAATTAGDY 401
SES M A L+ W+D+RL + + + LV E LW PD ++ + + +
Sbjct: 76 SESNMDYTATIYLRQRWMDQRLVFEGNKSFTLDARLV--EFLWVPDTYIVESKKSFLHEV 133
Query: 402 ALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNXDEMD 560
+ R+ +NG+V + R+ + +M L +P D QTC + S ++ ++++
Sbjct: 134 TVGNRLIRLFSNGTVLYALRITTTVACNMDLSKYPMDTQTCKLQLESWGYDGNDVE 189
>AB209359-1|BAD92596.1| 533|Homo sapiens cholinergic receptor,
nicotinic, alpha polypeptide 4 precursor variant
protein.
Length = 533
Score = 40.7 bits (91), Expect = 0.006
Identities = 25/91 (27%), Positives = 42/91 (46%), Gaps = 3/91 (3%)
Frame = +3
Query: 345 LWRPDVVLLNAAATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFK 524
LW +A A + +A + ++G V W + S+ + +P D Q CT K
Sbjct: 25 LWLCCCTFTSADGDFAVTHLTKAHLFHDGRVQWTPPAIYKSSCSIDVTFFPFDQQNCTMK 84
Query: 525 FGSRMHNXDEMDXV-IDKRI--YSMFESGAW 608
FGS ++ ++D V + R+ +ESG W
Sbjct: 85 FGSWTYDKAKIDLVNMHSRVDQLDFWESGEW 115
>BC096291-1|AAH96291.1| 556|Homo sapiens CHRNA4 protein protein.
Length = 556
Score = 39.9 bits (89), Expect = 0.011
Identities = 24/79 (30%), Positives = 41/79 (51%), Gaps = 7/79 (8%)
Frame = +3
Query: 393 GDYAL----RARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNXDEMD 560
GD+A+ +A + ++G V W + S+ + +P D Q CT KFGS ++ ++D
Sbjct: 60 GDFAVTHLTKAHLFHDGRVQWTPPAIYKSSCSIDVTFFPFDQQNCTMKFGSWTYDKAKID 119
Query: 561 XV-IDKRI--YSMFESGAW 608
V + R+ +ESG W
Sbjct: 120 LVNMHSRVDQLDFWESGEW 138
>U83981-1|AAC25631.1| 674|Homo sapiens apoptosis associated protein
protein.
Length = 674
Score = 31.1 bits (67), Expect = 5.0
Identities = 17/46 (36%), Positives = 22/46 (47%), Gaps = 1/46 (2%)
Frame = -1
Query: 420 IHGRGERSPRRWLQPRLAVPRQASTSVPRTPAKCCSP-TPLRSNSV 286
I+ GE+ P W PRL + Q P TP P TPL++ V
Sbjct: 511 IYVPGEKPPPPWAPPRLPLRLQRRLKRPETPTHDPDPETPLKARKV 556
>CR457259-1|CAG33540.1| 674|Homo sapiens PPP1R15A protein.
Length = 674
Score = 31.1 bits (67), Expect = 5.0
Identities = 17/46 (36%), Positives = 22/46 (47%), Gaps = 1/46 (2%)
Frame = -1
Query: 420 IHGRGERSPRRWLQPRLAVPRQASTSVPRTPAKCCSP-TPLRSNSV 286
I+ GE+ P W PRL + Q P TP P TPL++ V
Sbjct: 511 IYVPGEKPPPPWAPPRLPLRLQRRLKRPETPTHDPDPETPLKARKV 556
>BC003067-1|AAH03067.1| 674|Homo sapiens protein phosphatase 1,
regulatory (inhibitor) subunit 15A protein.
Length = 674
Score = 31.1 bits (67), Expect = 5.0
Identities = 17/46 (36%), Positives = 22/46 (47%), Gaps = 1/46 (2%)
Frame = -1
Query: 420 IHGRGERSPRRWLQPRLAVPRQASTSVPRTPAKCCSP-TPLRSNSV 286
I+ GE+ P W PRL + Q P TP P TPL++ V
Sbjct: 511 IYVPGEKPPPPWAPPRLPLRLQRRLKRPETPTHDPDPETPLKARKV 556
>AK001361-1|BAA91649.1| 674|Homo sapiens protein ( Homo sapiens
cDNA FLJ10499 fis, clone NT2RP2000346, weakly similar to
MYELOID DIFFERENTIATION PRIMARY RESPONSE PROTEIN MYD116.
).
Length = 674
Score = 31.1 bits (67), Expect = 5.0
Identities = 17/46 (36%), Positives = 22/46 (47%), Gaps = 1/46 (2%)
Frame = -1
Query: 420 IHGRGERSPRRWLQPRLAVPRQASTSVPRTPAKCCSP-TPLRSNSV 286
I+ GE+ P W PRL + Q P TP P TPL++ V
Sbjct: 511 IYVPGEKPPPPWAPPRLPLRLQRRLKRPETPTHDPDPETPLKARKV 556
>BC146774-1|AAI46775.1| 1114|Homo sapiens GPR124 protein protein.
Length = 1114
Score = 30.7 bits (66), Expect = 6.6
Identities = 16/55 (29%), Positives = 26/55 (47%), Gaps = 1/55 (1%)
Frame = +3
Query: 294 WNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNN-GSVSWIKRL 455
W +GEW C+ + + ++V+L T+ Y RV+NN G W + L
Sbjct: 314 WASGEWECTVSMAQGNASKKVEIVVLE----TSASYCPAERVANNRGDFRWPRTL 364
>AY181242-1|AAO27354.1| 1331|Homo sapiens G protein-coupled receptor
124 protein.
Length = 1331
Score = 30.7 bits (66), Expect = 6.6
Identities = 16/55 (29%), Positives = 26/55 (47%), Gaps = 1/55 (1%)
Frame = +3
Query: 294 WNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNN-GSVSWIKRL 455
W +GEW C+ + + ++V+L T+ Y RV+NN G W + L
Sbjct: 314 WASGEWECTVSMAQGNASKKVEIVVLE----TSASYCPAERVANNRGDFRWPRTL 364
>AK074099-1|BAB84925.1| 1310|Homo sapiens FLJ00170 protein protein.
Length = 1310
Score = 30.7 bits (66), Expect = 6.6
Identities = 16/55 (29%), Positives = 26/55 (47%), Gaps = 1/55 (1%)
Frame = +3
Query: 294 WNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNN-GSVSWIKRL 455
W +GEW C+ + + ++V+L T+ Y RV+NN G W + L
Sbjct: 293 WASGEWECTVSMAQGNASKKVEIVVLE----TSASYCPAERVANNRGDFRWPRTL 343
>AF378755-1|AAL11992.1| 1331|Homo sapiens tumor endothelial marker 5
precursor protein.
Length = 1331
Score = 30.7 bits (66), Expect = 6.6
Identities = 16/55 (29%), Positives = 26/55 (47%), Gaps = 1/55 (1%)
Frame = +3
Query: 294 WNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNN-GSVSWIKRL 455
W +GEW C+ + + ++V+L T+ Y RV+NN G W + L
Sbjct: 314 WASGEWECTVSMAQGNASKKVEIVVLE----TSASYCPAERVANNRGDFRWPRTL 364
>AB040964-1|BAA96055.2| 1206|Homo sapiens KIAA1531 protein protein.
Length = 1206
Score = 30.7 bits (66), Expect = 6.6
Identities = 16/55 (29%), Positives = 26/55 (47%), Gaps = 1/55 (1%)
Frame = +3
Query: 294 WNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNN-GSVSWIKRL 455
W +GEW C+ + + ++V+L T+ Y RV+NN G W + L
Sbjct: 406 WASGEWECTVSMAQGNASKKVEIVVLE----TSASYCPAERVANNRGDFRWPRTL 456
>AK122582-1|BAC56923.1| 1383|Homo sapiens FLJ00269 protein protein.
Length = 1383
Score = 30.3 bits (65), Expect = 8.8
Identities = 13/38 (34%), Positives = 18/38 (47%)
Frame = -1
Query: 417 HGRGERSPRRWLQPRLAVPRQASTSVPRTPAKCCSPTP 304
HG + SP W Q + + P + P P +CCS P
Sbjct: 256 HGGRDCSPTCWEQGKCSGPAEQEKRGPSFPKECCSQGP 293
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 114,642,527
Number of Sequences: 237096
Number of extensions: 2712975
Number of successful extensions: 7526
Number of sequences better than 10.0: 188
Number of HSP's better than 10.0 without gapping: 6530
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 7346
length of database: 76,859,062
effective HSP length: 89
effective length of database: 55,757,518
effective search space used: 10203625794
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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