Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BmNP10_FL5_I02
(824 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
AJ306454-1|CAC34819.1| 497|Homo sapiens neuronal nicotinic acet... 70 1e-11
Y08416-1|CAA69693.1| 498|Homo sapiens nicotinic acetylcholine r... 68 5e-11
U62439-1|AAB40117.1| 498|Homo sapiens nicotinic acetylcholine r... 68 5e-11
U48861-1|AAA92123.1| 498|Homo sapiens beta 4 nicotinic acetylch... 68 5e-11
BC096082-1|AAH96082.1| 498|Homo sapiens cholinergic receptor, n... 68 5e-11
BC096080-1|AAH96080.1| 498|Homo sapiens cholinergic receptor, n... 68 5e-11
AF306329-1|AAL02062.1| 498|Homo sapiens neuronal nicotinic acet... 68 5e-11
Y08417-1|CAA69694.1| 458|Homo sapiens nicotinic acetylcholine r... 65 3e-10
X67513-1|CAA47851.1| 423|Homo sapiens nicotinic acetylcholine ... 65 3e-10
U62438-1|AAB40116.1| 458|Homo sapiens nicotinic acetylcholine r... 65 3e-10
BC069788-1|AAH69788.1| 458|Homo sapiens cholinergic receptor, n... 65 3e-10
BC069703-1|AAH69703.1| 458|Homo sapiens cholinergic receptor, n... 65 3e-10
BC069681-1|AAH69681.1| 458|Homo sapiens cholinergic receptor, n... 65 3e-10
AF140765-1|AAD33063.1| 458|Homo sapiens neuronal acetylcholine ... 65 3e-10
X68275-1|CAA48336.1| 451|Homo sapiens nicotinic receptor beta 4... 64 8e-10
Y08419-1|CAA69696.1| 468|Homo sapiens nicotinic acetylcholine r... 63 1e-09
U62434-1|AAB40112.1| 468|Homo sapiens nicotinic acetylcholine r... 63 1e-09
BC033639-1|AAH33639.1| 468|Homo sapiens cholinergic receptor, n... 63 1e-09
AJ306481-1|CAC34820.1| 468|Homo sapiens neuronal nicotinic acet... 63 1e-09
Y08418-1|CAA69695.1| 503|Homo sapiens nicotinic acetylcholine r... 63 1e-09
X53559-1|CAA37625.1| 474|Homo sapiens neuronal nicotinic acetyl... 63 1e-09
U62432-1|AAB40110.1| 504|Homo sapiens nicotinic acetylcholine r... 63 1e-09
M37981-1|AAA59942.1| 503|Homo sapiens neuronal nicotinic acetyl... 63 1e-09
BT006897-1|AAP35543.1| 505|Homo sapiens cholinergic receptor, n... 63 1e-09
BT006646-1|AAP35292.1| 489|Homo sapiens cholinergic receptor, n... 63 1e-09
BC098443-1|AAH98443.1| 504|Homo sapiens cholinergic receptor, n... 63 1e-09
BC006114-1|AAH06114.1| 489|Homo sapiens CHRNA3 protein protein. 63 1e-09
BC002996-1|AAH02996.1| 505|Homo sapiens cholinergic receptor, n... 63 1e-09
BC001642-1|AAH01642.1| 505|Homo sapiens cholinergic receptor, n... 63 1e-09
BC000513-1|AAH00513.1| 505|Homo sapiens cholinergic receptor, n... 63 1e-09
AJ007783-1|CAA07682.1| 504|Homo sapiens nicotinic acetylcholine... 63 1e-09
AF385584-1|AAK68110.1| 489|Homo sapiens nicotinic cholinergic r... 63 1e-09
Y16282-1|CAA76155.1| 494|Homo sapiens nicotinic acetylcholine r... 62 2e-09
Y16281-1|CAA76154.1| 529|Homo sapiens nicotinic acetylcholine r... 62 2e-09
U62435-1|AAB40113.1| 494|Homo sapiens nicotinic acetylcholine r... 62 2e-09
U62431-1|AAB40109.1| 529|Homo sapiens nicotinic acetylcholine r... 62 2e-09
M83712-1|AAA58357.1| 468|Homo sapiens nicotinic receptor alpha ... 62 2e-09
BC014456-1|AAH14456.1| 494|Homo sapiens cholinergic receptor, n... 62 2e-09
AB079251-1|BAC06855.1| 494|Homo sapiens Nicotinic acetylcholine... 62 2e-09
X14830-1|CAA32939.1| 501|Homo sapiens protein ( Human mRNA for ... 62 3e-09
BC011371-1|AAH11371.1| 501|Homo sapiens cholinergic receptor, n... 62 3e-09
Y08421-1|CAA69698.1| 627|Homo sapiens nicotinic acetylcholine r... 60 7e-09
X89741-1|CAA61893.1| 627|Homo sapiens neuronal acetylcholine re... 60 7e-09
X87629-1|CAA60959.1| 602|Homo sapiens nicotinic acetylcholine r... 60 7e-09
U62433-1|AAB40111.1| 627|Homo sapiens nicotinic acetylcholine r... 60 7e-09
M86383-1|AAC84176.1| 502|Homo sapiens nicotinic acetylcholine r... 60 7e-09
L35901-1|AAA64743.1| 627|Homo sapiens nicotinic acetylcholine r... 60 7e-09
DQ093071-1|AAY88737.1| 627|Homo sapiens cholinergic receptor, n... 60 7e-09
BC096290-1|AAH96290.1| 627|Homo sapiens cholinergic receptor, n... 60 7e-09
BC023553-1|AAH23553.1| 501|Homo sapiens cholinergic receptor, n... 60 7e-09
Y00762-1|CAA68731.1| 457|Homo sapiens protein ( Human mRNA for ... 60 1e-08
X02502-1|CAA26344.1| 457|Homo sapiens acetylcholine receptor pr... 60 1e-08
S77094-1|AAD14247.1| 457|Homo sapiens nicotinic acetylcholine r... 60 1e-08
BC006314-1|AAH06314.1| 269|Homo sapiens CHRNA1 protein protein. 60 1e-08
AC018890-1|AAY14687.1| 457|Homo sapiens unknown protein. 60 1e-08
Y08415-1|CAA69692.1| 502|Homo sapiens nicotinic acetylcholine r... 56 1e-07
X53179-1|CAA37320.1| 502|Homo sapiens precursor peptide (AA -25... 56 1e-07
X01715-1|CAA25861.1| 520|Homo sapiens acetylcholine receptor ga... 56 1e-07
U62437-1|AAB40115.1| 502|Homo sapiens nicotinic acetylcholine r... 56 1e-07
BC075041-1|AAH75041.1| 502|Homo sapiens cholinergic receptor, n... 56 1e-07
BC075040-1|AAH75040.1| 502|Homo sapiens cholinergic receptor, n... 56 1e-07
AL592078-3|CAI16184.1| 502|Homo sapiens cholinergic receptor, n... 56 1e-07
AJ001935-1|CAA05108.1| 504|Homo sapiens CHRNB2 protein. 56 1e-07
AF077186-1|AAD45422.1| 502|Homo sapiens neuronal nicotinic acet... 56 1e-07
AC092165-3|AAY24103.1| 520|Homo sapiens unknown protein. 56 1e-07
X55019-1|CAA38759.1| 517|Homo sapiens acetylcholine receptor de... 56 2e-07
BC093925-1|AAH93925.1| 517|Homo sapiens cholinergic receptor, n... 56 2e-07
BC093923-1|AAH93923.1| 517|Homo sapiens cholinergic receptor, n... 56 2e-07
AC092165-2|AAY24102.1| 517|Homo sapiens unknown protein. 56 2e-07
X66403-1|CAA47030.1| 493|Homo sapiens acetylcholine receptor ep... 55 3e-07
AF105999-1|AAD24503.1| 493|Homo sapiens acetylcholine receptor ... 55 3e-07
Z23141-1|CAA80672.1| 479|Homo sapiens cholinergic receptor, nic... 53 1e-06
Y08420-1|CAA69697.1| 502|Homo sapiens nicotinic acetylcholine r... 53 1e-06
X70297-1|CAA49778.1| 502|Homo sapiens neuronal nicotinic acetyl... 53 1e-06
U62436-1|AAB40114.1| 502|Homo sapiens nicotinic acetylcholine r... 53 1e-06
DQ644022-1|ABG35128.1| 456|Homo sapiens 5-HT3 receptor subunit ... 53 1e-06
BC101185-1|AAI01186.1| 374|Homo sapiens HTR3E protein protein. 53 1e-06
BC101183-1|AAI01184.1| 471|Homo sapiens 5-hydroxytryptamine (se... 53 1e-06
BC101182-1|AAI01183.1| 471|Homo sapiens 5-hydroxytryptamine (se... 53 1e-06
AY159813-1|AAO38167.2| 471|Homo sapiens 5-hydroxytryptamine ser... 53 1e-06
AJ586911-1|CAE52911.1| 502|Homo sapiens nicotinic acetylcholine... 53 1e-06
AJ295237-1|CAC16144.1| 450|Homo sapiens neuronal nicotinic acet... 53 1e-06
AJ278118-1|CAC20435.1| 450|Homo sapiens neuronal nicotinic acet... 53 1e-06
AF327367-1|AAK14333.1| 450|Homo sapiens nicotinic acetylcholine... 53 1e-06
AF199235-1|AAG00795.2| 450|Homo sapiens nicotinic acetylcholine... 53 1e-06
AK122638-1|BAC85499.1| 266|Homo sapiens yte protein of 76kDa) (... 52 3e-06
U40583-1|AAA83561.1| 502|Homo sapiens alpha 7 neuronal nicotini... 52 3e-06
BC131799-1|AAI31800.1| 447|Homo sapiens 5-hydroxytryptamine (se... 52 3e-06
AY349353-1|AAQ93477.1| 456|Homo sapiens 5-HT3c1 serotonin recep... 52 3e-06
AY349352-1|AAQ93476.1| 441|Homo sapiens 5-HT3c1 serotonin recep... 52 3e-06
AF385585-1|AAK68111.1| 502|Homo sapiens nicotinic cholinergic r... 52 3e-06
BC110597-1|AAI10598.1| 411|Homo sapiens ligand-gated ion channe... 51 4e-06
AF512521-1|AAO20969.1| 411|Homo sapiens ligand-gated ion channe... 51 4e-06
AF459285-1|AAL66182.1| 447|Homo sapiens 5-hydroxytryptamine rec... 51 4e-06
BC113575-1|AAI13576.1| 479|Homo sapiens cholinergic receptor, n... 51 6e-06
BC113549-1|AAI13550.1| 479|Homo sapiens cholinergic receptor, n... 51 6e-06
BC111802-1|AAI11803.1| 465|Homo sapiens CHRNG protein protein. 51 6e-06
AY123244-1|AAM74523.1| 479|Homo sapiens nicotinic acetylcholine... 51 6e-06
AJ243342-1|CAB65091.1| 479|Homo sapiens nicotinic acetylcholine... 51 6e-06
AF227732-1|AAF61920.1| 470|Homo sapiens nicotinic acetylcholine... 51 6e-06
AC118275-1|AAY40986.1| 479|Homo sapiens unknown protein. 51 6e-06
AB223030-1|BAE19924.1| 411|Homo sapiens ligand-gated ion-channe... 51 6e-06
U77731-2|AAB38273.1| 360|Homo sapiens glycine receptor alpha 2B... 50 1e-05
L08485-1|AAA58490.1| 462|Homo sapiens GABA-benzodiazepine recep... 50 1e-05
CR450343-1|CAG29339.1| 452|Homo sapiens GLRA2 protein. 50 1e-05
BT009830-1|AAP88832.1| 462|Homo sapiens gamma-aminobutyric acid... 50 1e-05
BC113422-1|AAI13423.1| 462|Homo sapiens gamma-aminobutyric acid... 50 1e-05
BC111979-1|AAI11980.1| 462|Homo sapiens gamma-aminobutyric acid... 50 1e-05
AY437084-1|AAR87843.1| 452|Homo sapiens glycine receptor alpha2... 50 1e-05
X52008-1|CAA36257.1| 452|Homo sapiens inhibitory glycine recept... 50 1e-05
U77731-1|AAB38272.1| 360|Homo sapiens glycine receptor alpha 2 ... 50 1e-05
BC032864-1|AAH32864.1| 452|Homo sapiens glycine receptor, alpha... 50 1e-05
AY437083-1|AAR87842.1| 452|Homo sapiens glycine receptor alpha2... 50 1e-05
AF053495-1|AAC35290.1| 452|Homo sapiens glycine receptor alpha ... 50 1e-05
BC028629-1|AAH28629.1| 492|Homo sapiens gamma-aminobutyric acid... 49 2e-05
S62908-1|AAB27279.1| 492|Homo sapiens gamma-aminobutyric acidA ... 48 3e-05
AF166361-1|AAG12455.1| 492|Homo sapiens GABA receptor subunit a... 48 3e-05
M59216-1|AAA35862.1| 474|Homo sapiens gamma-aminobutyric acid r... 48 4e-05
S77554-1|AAB33983.1| 474|Homo sapiens GABAA receptor beta 2 sub... 48 5e-05
S77553-1|AAB33982.1| 512|Homo sapiens GABAA receptor beta 2 sub... 48 5e-05
S67368-1|AAB29370.1| 474|Homo sapiens gamma-aminobutyric acid A... 48 5e-05
S62907-1|AAB27278.1| 451|Homo sapiens gamma-aminobutyric acidA ... 48 5e-05
BC105639-1|AAI05640.1| 474|Homo sapiens GABRB2 protein protein. 48 5e-05
BC099719-1|AAH99719.1| 474|Homo sapiens GABRB2 protein protein. 48 5e-05
BC099705-1|AAH99705.1| 474|Homo sapiens GABRB2 protein protein. 48 5e-05
BC022488-1|AAH22488.1| 367|Homo sapiens GABRA2 protein protein. 48 5e-05
AB209295-1|BAD92532.1| 461|Homo sapiens gamma-aminobutyric acid... 48 5e-05
X14767-1|CAA32875.1| 474|Homo sapiens GABA-A receptor beta 1 su... 47 7e-05
BC096083-1|AAH96083.1| 198|Homo sapiens CHRNB4 protein protein. 47 7e-05
BC096081-1|AAH96081.1| 198|Homo sapiens CHRNB4 protein protein. 47 7e-05
S82769-1|AAB39369.1| 467|Homo sapiens GABAA receptor gamma 3 su... 47 1e-04
S82612-1|AAB37533.2| 478|Homo sapiens 5-hydroxytryptamine type ... 47 1e-04
AF269144-1|AAF99698.1| 467|Homo sapiens GABAA receptor gamma 3 ... 47 1e-04
AF228458-1|AAF63215.1| 449|Homo sapiens GABAA receptor gamma 3 ... 47 1e-04
U33267-1|AAB37750.1| 497|Homo sapiens glycine receptor beta sub... 46 1e-04
S81944-1|AAB36480.1| 453|Homo sapiens gamma-aminobutyric acid t... 46 1e-04
D49394-1|BAA08387.1| 478|Homo sapiens serotonin 5-HT3 receptor ... 46 1e-04
BT007204-1|AAP35868.1| 484|Homo sapiens 5-hydroxytryptamine (se... 46 1e-04
BC099641-1|AAH99641.1| 453|Homo sapiens gamma-aminobutyric acid... 46 1e-04
BC099640-1|AAH99640.1| 453|Homo sapiens gamma-aminobutyric acid... 46 1e-04
BC096242-1|AAH96242.1| 453|Homo sapiens gamma-aminobutyric acid... 46 1e-04
BC096241-1|AAH96241.1| 453|Homo sapiens gamma-aminobutyric acid... 46 1e-04
BC032635-1|AAH32635.1| 497|Homo sapiens glycine receptor, beta ... 46 1e-04
BC004453-1|AAH04453.2| 478|Homo sapiens 5-hydroxytryptamine (se... 46 1e-04
BC002354-1|AAH02354.1| 478|Homo sapiens 5-hydroxytryptamine (se... 46 1e-04
AJ005205-1|CAA06442.3| 478|Homo sapiens serotonin 3 receptor pr... 46 1e-04
AJ003080-1|CAA05853.1| 238|Homo sapiens serotonin receptor prot... 46 1e-04
AJ003079-1|CAA05852.1| 478|Homo sapiens 5-hydroxytryptamine3 re... 46 1e-04
AJ003078-1|CAA05851.1| 510|Homo sapiens serotonin receptor prot... 46 1e-04
AF498984-1|AAM21131.1| 478|Homo sapiens 5-hydroxytryptamine rec... 46 1e-04
AF094755-1|AAC71034.1| 497|Homo sapiens glycine receptor beta s... 46 1e-04
AF094754-1|AAC71033.1| 497|Homo sapiens glycine receptor beta s... 46 1e-04
M82919-1|AAA52511.1| 473|Homo sapiens GABA-alpha receptor beta-... 46 2e-04
BC109211-1|AAI09212.1| 632|Homo sapiens gamma-aminobutyric acid... 46 2e-04
BC109210-1|AAI09211.1| 632|Homo sapiens gamma-aminobutyric acid... 46 2e-04
BC030696-1|AAH30696.1| 456|Homo sapiens GABRA1 protein protein. 46 2e-04
AK223447-1|BAD97167.1| 456|Homo sapiens gamma-aminobutyric acid... 46 2e-04
AF189259-1|AAF70380.1| 632|Homo sapiens GABA-A receptor theta s... 46 2e-04
AF144648-1|AAD51172.1| 627|Homo sapiens GABA-A receptor theta p... 46 2e-04
X52009-1|CAA36258.1| 449|Homo sapiens inhibitory glycine recept... 46 2e-04
U30461-1|AAB52519.1| 554|Homo sapiens GABAA receptor subunit al... 46 2e-04
BC114947-1|AAI14948.1| 457|Homo sapiens GLRA1 protein protein. 46 2e-04
BC074980-1|AAH74980.1| 449|Homo sapiens glycine receptor, alpha... 46 2e-04
BC035055-1|AAH35055.1| 554|Homo sapiens gamma-aminobutyric acid... 46 2e-04
BC033801-1|AAH33801.1| 452|Homo sapiens gamma-aminobutyric acid... 46 2e-04
AL391845-4|CAI15436.1| 452|Homo sapiens gamma-aminobutyric acid... 46 2e-04
AF016917-1|AAB70007.1| 452|Homo sapiens GABA-A receptor delta s... 46 2e-04
Z93848-1|CAI41994.1| 376|Homo sapiens glycine receptor, alpha 4... 44 5e-04
AL049610-1|CAI42158.1| 376|Homo sapiens glycine receptor, alpha... 44 5e-04
U93917-1|AAC39917.1| 449|Homo sapiens glycine receptor alpha 3 ... 44 7e-04
BC036086-1|AAH36086.1| 464|Homo sapiens glycine receptor, alpha... 44 7e-04
AF017724-1|AAC39919.1| 465|Homo sapiens glycine receptor alpha ... 44 7e-04
U95367-1|AAC51357.1| 440|Homo sapiens GABA-A receptor pi subuni... 44 9e-04
BC109106-1|AAI09107.1| 440|Homo sapiens gamma-aminobutyric acid... 44 9e-04
BC109105-1|AAI09106.1| 440|Homo sapiens gamma-aminobutyric acid... 44 9e-04
BC074865-1|AAH74865.1| 440|Homo sapiens gamma-aminobutyric acid... 44 9e-04
BC074810-1|AAH74810.1| 440|Homo sapiens gamma-aminobutyric acid... 44 9e-04
AF009702-1|AAC24194.1| 440|Homo sapiens GABA-A receptor pi subu... 44 9e-04
BC114967-1|AAI14968.1| 366|Homo sapiens GLRA1 protein protein. 43 0.001
BC010641-1|AAH10641.1| 473|Homo sapiens gamma-aminobutyric acid... 43 0.001
BC022449-1|AAH22449.1| 474|Homo sapiens gamma-aminobutyric acid... 43 0.002
AC093745-1|AAY40994.1| 222|Homo sapiens unknown protein. 43 0.002
X13584-1|CAA31925.1| 354|Homo sapiens protein ( Human mRNA for ... 42 0.003
BC074795-1|AAH74795.1| 467|Homo sapiens gamma-aminobutyric acid... 42 0.003
BC069348-1|AAH69348.1| 467|Homo sapiens gamma-aminobutyric acid... 42 0.003
BC059389-1|AAH59389.1| 475|Homo sapiens gamma-aminobutyric acid... 42 0.003
AF165124-1|AAD50273.1| 467|Homo sapiens gamma-aminobutyric acid... 42 0.003
X15376-1|CAA33437.1| 467|Homo sapiens GABA-A receptor gamma 2 s... 41 0.006
X14766-1|CAA32874.1| 456|Homo sapiens GABA-A receptor alpha 1 s... 40 0.008
BC031087-1|AAH31087.1| 465|Homo sapiens gamma-aminobutyric acid... 40 0.008
M86868-1|AAA52510.1| 465|Homo sapiens gamma-amino butyric acid ... 38 0.044
BC130354-1|AAI30355.1| 465|Homo sapiens gamma-aminobutyric acid... 38 0.044
BC130352-1|AAI30353.1| 465|Homo sapiens gamma-aminobutyric acid... 38 0.044
AL121833-2|CAC07339.1| 465|Homo sapiens gamma-aminobutyric acid... 38 0.044
AM293589-1|CAL25321.1| 430|Homo sapiens 5-hydroxytryptamine rec... 36 0.13
AF169255-1|AAF03691.1| 441|Homo sapiens 5-hydroxytryptamine 3 r... 35 0.31
AF080582-1|AAD12242.1| 441|Homo sapiens 5-hydroxytryptamine 3 r... 35 0.31
M62400-1|AAA52509.1| 473|Homo sapiens gamma-aminobutyric acid r... 35 0.41
BC130344-1|AAI30345.1| 474|Homo sapiens gamma-aminobutyric acid... 35 0.41
AL353659-1|CAC36328.2| 473|Homo sapiens gamma-aminobutyric acid... 35 0.41
AL353135-3|CAI16246.1| 473|Homo sapiens gamma-aminobutyric acid... 35 0.41
BC096291-1|AAH96291.1| 556|Homo sapiens CHRNA4 protein protein. 34 0.54
AB209359-1|BAD92596.1| 533|Homo sapiens cholinergic receptor, n... 34 0.54
U83981-1|AAC25631.1| 674|Homo sapiens apoptosis associated prot... 31 5.1
CR457259-1|CAG33540.1| 674|Homo sapiens PPP1R15A protein. 31 5.1
BC003067-1|AAH03067.1| 674|Homo sapiens protein phosphatase 1, ... 31 5.1
AK001361-1|BAA91649.1| 674|Homo sapiens protein ( Homo sapiens ... 31 5.1
BC146774-1|AAI46775.1| 1114|Homo sapiens GPR124 protein protein. 31 6.7
AY181242-1|AAO27354.1| 1331|Homo sapiens G protein-coupled recep... 31 6.7
AK074099-1|BAB84925.1| 1310|Homo sapiens FLJ00170 protein protein. 31 6.7
AF378755-1|AAL11992.1| 1331|Homo sapiens tumor endothelial marke... 31 6.7
AB040964-1|BAA96055.2| 1206|Homo sapiens KIAA1531 protein protein. 31 6.7
AK122582-1|BAC56923.1| 1383|Homo sapiens FLJ00269 protein protein. 30 8.8
>AJ306454-1|CAC34819.1| 497|Homo sapiens neuronal nicotinic
acetylcholine receptor beta-4 subunit protein.
Length = 497
Score = 69.7 bits (163), Expect = 1e-11
Identities = 44/159 (27%), Positives = 74/159 (46%), Gaps = 8/159 (5%)
Frame = +2
Query: 95 AIASAAECENATSLSLMIDSLL--ATYD---RDSPPDSKIV-VNLTLHLRHA-NIRESES 253
A+ C A + ++D LL Y+ R + S+++ + L L L ++ E E
Sbjct: 14 ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQ 73
Query: 254 TVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTXGDYALRAR 430
+ L+ W D RL+WN+ + G + + ++R+W PD+VL N T
Sbjct: 74 IMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNDGTYEVSVYTNLI 133
Query: 431 VSNNGSVSWIKRLDISTPISMQLDNWPXDMQTCTFKFGS 547
V +NGSV W+ + +++ +P D Q CT KF S
Sbjct: 134 VRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRS 172
>Y08416-1|CAA69693.1| 498|Homo sapiens nicotinic acetylcholine
receptor beta4 subunit precursor protein.
Length = 498
Score = 67.7 bits (158), Expect = 5e-11
Identities = 45/160 (28%), Positives = 75/160 (46%), Gaps = 9/160 (5%)
Frame = +2
Query: 95 AIASAAECENATSLSLMIDSLL--ATYD---RDSPPDSKIV-VNLTLHLRHA-NIRESES 253
A+ C A + ++D LL Y+ R + S+++ + L L L ++ E E
Sbjct: 14 ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQ 73
Query: 254 TVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTXGDYALRA 427
+ L+ W D RL+WN+ + G + + ++R+W PD+VL N A T
Sbjct: 74 IMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNADGTYEVSVYTNL 133
Query: 428 RVSNNGSVSWIKRLDISTPISMQLDNWPXDMQTCTFKFGS 547
V +NGSV W+ + +++ +P D Q CT KF S
Sbjct: 134 IVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRS 173
>U62439-1|AAB40117.1| 498|Homo sapiens nicotinic acetylcholine
receptor beta4 subunit precursor protein.
Length = 498
Score = 67.7 bits (158), Expect = 5e-11
Identities = 45/160 (28%), Positives = 75/160 (46%), Gaps = 9/160 (5%)
Frame = +2
Query: 95 AIASAAECENATSLSLMIDSLL--ATYD---RDSPPDSKIV-VNLTLHLRHA-NIRESES 253
A+ C A + ++D LL Y+ R + S+++ + L L L ++ E E
Sbjct: 14 ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQ 73
Query: 254 TVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTXGDYALRA 427
+ L+ W D RL+WN+ + G + + ++R+W PD+VL N A T
Sbjct: 74 IMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNADGTYEVSVYTNL 133
Query: 428 RVSNNGSVSWIKRLDISTPISMQLDNWPXDMQTCTFKFGS 547
V +NGSV W+ + +++ +P D Q CT KF S
Sbjct: 134 IVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRS 173
>U48861-1|AAA92123.1| 498|Homo sapiens beta 4 nicotinic
acetylcholine receptor subunit protein.
Length = 498
Score = 67.7 bits (158), Expect = 5e-11
Identities = 45/160 (28%), Positives = 75/160 (46%), Gaps = 9/160 (5%)
Frame = +2
Query: 95 AIASAAECENATSLSLMIDSLL--ATYD---RDSPPDSKIV-VNLTLHLRHA-NIRESES 253
A+ C A + ++D LL Y+ R + S+++ + L L L ++ E E
Sbjct: 14 ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQ 73
Query: 254 TVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTXGDYALRA 427
+ L+ W D RL+WN+ + G + + ++R+W PD+VL N A T
Sbjct: 74 IMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNADGTYEVSVYTNL 133
Query: 428 RVSNNGSVSWIKRLDISTPISMQLDNWPXDMQTCTFKFGS 547
V +NGSV W+ + +++ +P D Q CT KF S
Sbjct: 134 IVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRS 173
>BC096082-1|AAH96082.1| 498|Homo sapiens cholinergic receptor,
nicotinic, beta 4 protein.
Length = 498
Score = 67.7 bits (158), Expect = 5e-11
Identities = 45/160 (28%), Positives = 75/160 (46%), Gaps = 9/160 (5%)
Frame = +2
Query: 95 AIASAAECENATSLSLMIDSLL--ATYD---RDSPPDSKIV-VNLTLHLRHA-NIRESES 253
A+ C A + ++D LL Y+ R + S+++ + L L L ++ E E
Sbjct: 14 ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQ 73
Query: 254 TVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTXGDYALRA 427
+ L+ W D RL+WN+ + G + + ++R+W PD+VL N A T
Sbjct: 74 IMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNADGTYEVSVYTNL 133
Query: 428 RVSNNGSVSWIKRLDISTPISMQLDNWPXDMQTCTFKFGS 547
V +NGSV W+ + +++ +P D Q CT KF S
Sbjct: 134 IVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRS 173
>BC096080-1|AAH96080.1| 498|Homo sapiens cholinergic receptor,
nicotinic, beta 4 protein.
Length = 498
Score = 67.7 bits (158), Expect = 5e-11
Identities = 45/160 (28%), Positives = 75/160 (46%), Gaps = 9/160 (5%)
Frame = +2
Query: 95 AIASAAECENATSLSLMIDSLL--ATYD---RDSPPDSKIV-VNLTLHLRHA-NIRESES 253
A+ C A + ++D LL Y+ R + S+++ + L L L ++ E E
Sbjct: 14 ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQ 73
Query: 254 TVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTXGDYALRA 427
+ L+ W D RL+WN+ + G + + ++R+W PD+VL N A T
Sbjct: 74 IMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNADGTYEVSVYTNL 133
Query: 428 RVSNNGSVSWIKRLDISTPISMQLDNWPXDMQTCTFKFGS 547
V +NGSV W+ + +++ +P D Q CT KF S
Sbjct: 134 IVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRS 173
>AF306329-1|AAL02062.1| 498|Homo sapiens neuronal nicotinic
acetylcholine receptor beta 4 subunit protein.
Length = 498
Score = 67.7 bits (158), Expect = 5e-11
Identities = 45/160 (28%), Positives = 75/160 (46%), Gaps = 9/160 (5%)
Frame = +2
Query: 95 AIASAAECENATSLSLMIDSLL--ATYD---RDSPPDSKIV-VNLTLHLRHA-NIRESES 253
A+ C A + ++D LL Y+ R + S+++ + L L L ++ E E
Sbjct: 14 ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQ 73
Query: 254 TVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTXGDYALRA 427
+ L+ W D RL+WN+ + G + + ++R+W PD+VL N A T
Sbjct: 74 IMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNADGTYEVSVYTNL 133
Query: 428 RVSNNGSVSWIKRLDISTPISMQLDNWPXDMQTCTFKFGS 547
V +NGSV W+ + +++ +P D Q CT KF S
Sbjct: 134 IVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRS 173
>Y08417-1|CAA69694.1| 458|Homo sapiens nicotinic acetylcholine
receptor beta3 subunit precursor protein.
Length = 458
Score = 65.3 bits (152), Expect = 3e-10
Identities = 34/107 (31%), Positives = 51/107 (47%), Gaps = 2/107 (1%)
Frame = +2
Query: 233 NIRESESTVRIQADLQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLL-NAAATTX 406
++ E + L+ W D +L WN ++G + V SE LW PD+VL NA
Sbjct: 67 DVDEKNQLMTTNVWLKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFE 126
Query: 407 GDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPXDMQTCTFKFGS 547
G + V +NG+V W + +M + +P D Q C+ KFGS
Sbjct: 127 GSLMTKVIVKSNGTVVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGS 173
>X67513-1|CAA47851.1| 423|Homo sapiens nicotinic acetylcholine
receptor beta-3 subunit protein.
Length = 423
Score = 65.3 bits (152), Expect = 3e-10
Identities = 34/107 (31%), Positives = 51/107 (47%), Gaps = 2/107 (1%)
Frame = +2
Query: 233 NIRESESTVRIQADLQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLL-NAAATTX 406
++ E + L+ W D +L WN ++G + V SE LW PD+VL NA
Sbjct: 32 DVDEKNQLMTTNVWLKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFE 91
Query: 407 GDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPXDMQTCTFKFGS 547
G + V +NG+V W + +M + +P D Q C+ KFGS
Sbjct: 92 GSLMTKVIVKSNGTVVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGS 138
>U62438-1|AAB40116.1| 458|Homo sapiens nicotinic acetylcholine
receptor beta3 subunit precursor protein.
Length = 458
Score = 65.3 bits (152), Expect = 3e-10
Identities = 34/107 (31%), Positives = 51/107 (47%), Gaps = 2/107 (1%)
Frame = +2
Query: 233 NIRESESTVRIQADLQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLL-NAAATTX 406
++ E + L+ W D +L WN ++G + V SE LW PD+VL NA
Sbjct: 67 DVDEKNQLMTTNVWLKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFE 126
Query: 407 GDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPXDMQTCTFKFGS 547
G + V +NG+V W + +M + +P D Q C+ KFGS
Sbjct: 127 GSLMTKVIVKSNGTVVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGS 173
>BC069788-1|AAH69788.1| 458|Homo sapiens cholinergic receptor,
nicotinic, beta 3 protein.
Length = 458
Score = 65.3 bits (152), Expect = 3e-10
Identities = 34/107 (31%), Positives = 51/107 (47%), Gaps = 2/107 (1%)
Frame = +2
Query: 233 NIRESESTVRIQADLQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLL-NAAATTX 406
++ E + L+ W D +L WN ++G + V SE LW PD+VL NA
Sbjct: 67 DVDEKNQLMTTNVWLKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFE 126
Query: 407 GDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPXDMQTCTFKFGS 547
G + V +NG+V W + +M + +P D Q C+ KFGS
Sbjct: 127 GSLMTKVIVKSNGTVVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGS 173
>BC069703-1|AAH69703.1| 458|Homo sapiens cholinergic receptor,
nicotinic, beta 3 protein.
Length = 458
Score = 65.3 bits (152), Expect = 3e-10
Identities = 34/107 (31%), Positives = 51/107 (47%), Gaps = 2/107 (1%)
Frame = +2
Query: 233 NIRESESTVRIQADLQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLL-NAAATTX 406
++ E + L+ W D +L WN ++G + V SE LW PD+VL NA
Sbjct: 67 DVDEKNQLMTTNVWLKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFE 126
Query: 407 GDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPXDMQTCTFKFGS 547
G + V +NG+V W + +M + +P D Q C+ KFGS
Sbjct: 127 GSLMTKVIVKSNGTVVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGS 173
>BC069681-1|AAH69681.1| 458|Homo sapiens cholinergic receptor,
nicotinic, beta 3 protein.
Length = 458
Score = 65.3 bits (152), Expect = 3e-10
Identities = 34/107 (31%), Positives = 51/107 (47%), Gaps = 2/107 (1%)
Frame = +2
Query: 233 NIRESESTVRIQADLQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLL-NAAATTX 406
++ E + L+ W D +L WN ++G + V SE LW PD+VL NA
Sbjct: 67 DVDEKNQLMTTNVWLKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFE 126
Query: 407 GDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPXDMQTCTFKFGS 547
G + V +NG+V W + +M + +P D Q C+ KFGS
Sbjct: 127 GSLMTKVIVKSNGTVVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGS 173
>AF140765-1|AAD33063.1| 458|Homo sapiens neuronal acetylcholine
receptor beta-3 subunit precursor protein.
Length = 458
Score = 65.3 bits (152), Expect = 3e-10
Identities = 34/107 (31%), Positives = 51/107 (47%), Gaps = 2/107 (1%)
Frame = +2
Query: 233 NIRESESTVRIQADLQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLL-NAAATTX 406
++ E + L+ W D +L WN ++G + V SE LW PD+VL NA
Sbjct: 67 DVDEKNQLMTTNVWLKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFE 126
Query: 407 GDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPXDMQTCTFKFGS 547
G + V +NG+V W + +M + +P D Q C+ KFGS
Sbjct: 127 GSLMTKVIVKSNGTVVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGS 173
>X68275-1|CAA48336.1| 451|Homo sapiens nicotinic receptor beta 4
subunit protein.
Length = 451
Score = 63.7 bits (148), Expect = 8e-10
Identities = 36/120 (30%), Positives = 58/120 (48%), Gaps = 3/120 (2%)
Frame = +2
Query: 197 IVVNLTLHLRHA-NIRESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 370
I + L L L ++ E + + L+ W D RL+WN+ + G + + ++R+W P
Sbjct: 7 ISIKLQLSLAQLISVNERDEIMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLP 66
Query: 371 DVVLLNAA-ATTXGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPXDMQTCTFKFGS 547
D+VL N A T V +NGSV W+ + +++ +P D Q CT KF S
Sbjct: 67 DIVLYNNADGTYEVSVYTNLIVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRS 126
>Y08419-1|CAA69696.1| 468|Homo sapiens nicotinic acetylcholine
receptor alpha5 subunit precursor protein.
Length = 468
Score = 63.3 bits (147), Expect = 1e-09
Identities = 36/141 (25%), Positives = 66/141 (46%), Gaps = 6/141 (4%)
Frame = +2
Query: 143 MIDSLLATYDRDSPP----DSKIVVNLTLHLRH-ANIRESESTVRIQADLQMNWIDKRLS 307
++ L Y+R P + KI + L + ++ E + L+ WID +L
Sbjct: 50 LLKDLFQDYERWVRPVEHLNDKIKIKFGLAISQLVDVDEKNQLMTTNVWLKQEWIDVKLR 109
Query: 308 WNAGEWG-CSTWLVSSERLWRPDVVLLNAAATTXGDYALRARVSNNGSVSWIKRLDISTP 484
WN ++G V S+ +W PD+VL + A + + + NG+V+W + +
Sbjct: 110 WNPDDYGGIKVIRVPSDSVWTPDIVLFDNADGRFEGTSTKTVIRYNGTVTWTPPANYKSS 169
Query: 485 ISMQLDNWPXDMQTCTFKFGS 547
++ + +P D+Q C+ KFGS
Sbjct: 170 CTIDVTFFPFDLQNCSMKFGS 190
>U62434-1|AAB40112.1| 468|Homo sapiens nicotinic acetylcholine
receptor alpha5 subunit precursor protein.
Length = 468
Score = 63.3 bits (147), Expect = 1e-09
Identities = 36/141 (25%), Positives = 66/141 (46%), Gaps = 6/141 (4%)
Frame = +2
Query: 143 MIDSLLATYDRDSPP----DSKIVVNLTLHLRH-ANIRESESTVRIQADLQMNWIDKRLS 307
++ L Y+R P + KI + L + ++ E + L+ WID +L
Sbjct: 50 LLKDLFQDYERWVRPVEHLNDKIKIKFGLAISQLVDVDEKNQLMTTNVWLKQEWIDVKLR 109
Query: 308 WNAGEWG-CSTWLVSSERLWRPDVVLLNAAATTXGDYALRARVSNNGSVSWIKRLDISTP 484
WN ++G V S+ +W PD+VL + A + + + NG+V+W + +
Sbjct: 110 WNPDDYGGIKVIRVPSDSVWTPDIVLFDNADGRFEGTSTKTVIRYNGTVTWTPPANYKSS 169
Query: 485 ISMQLDNWPXDMQTCTFKFGS 547
++ + +P D+Q C+ KFGS
Sbjct: 170 CTIDVTFFPFDLQNCSMKFGS 190
>BC033639-1|AAH33639.1| 468|Homo sapiens cholinergic receptor,
nicotinic, alpha 5 protein.
Length = 468
Score = 63.3 bits (147), Expect = 1e-09
Identities = 36/141 (25%), Positives = 66/141 (46%), Gaps = 6/141 (4%)
Frame = +2
Query: 143 MIDSLLATYDRDSPP----DSKIVVNLTLHLRH-ANIRESESTVRIQADLQMNWIDKRLS 307
++ L Y+R P + KI + L + ++ E + L+ WID +L
Sbjct: 50 LLKDLFQDYERWVRPVEHLNDKIKIKFGLAISQLVDVDEKNQLMTTNVWLKQEWIDVKLR 109
Query: 308 WNAGEWG-CSTWLVSSERLWRPDVVLLNAAATTXGDYALRARVSNNGSVSWIKRLDISTP 484
WN ++G V S+ +W PD+VL + A + + + NG+V+W + +
Sbjct: 110 WNPDDYGGIKVIRVPSDSVWTPDIVLFDNADGRFEGTSTKTVIRYNGTVTWTPPANYKSS 169
Query: 485 ISMQLDNWPXDMQTCTFKFGS 547
++ + +P D+Q C+ KFGS
Sbjct: 170 CTIDVTFFPFDLQNCSMKFGS 190
>AJ306481-1|CAC34820.1| 468|Homo sapiens neuronal nicotinic
acetylcholine receptor alpha-5subunit protein.
Length = 468
Score = 63.3 bits (147), Expect = 1e-09
Identities = 36/141 (25%), Positives = 66/141 (46%), Gaps = 6/141 (4%)
Frame = +2
Query: 143 MIDSLLATYDRDSPP----DSKIVVNLTLHLRH-ANIRESESTVRIQADLQMNWIDKRLS 307
++ L Y+R P + KI + L + ++ E + L+ WID +L
Sbjct: 50 LLKDLFQDYERWVRPVEHLNDKIKIKFGLAISQLVDVDEKNQLMTTNVWLKQEWIDVKLR 109
Query: 308 WNAGEWG-CSTWLVSSERLWRPDVVLLNAAATTXGDYALRARVSNNGSVSWIKRLDISTP 484
WN ++G V S+ +W PD+VL + A + + + NG+V+W + +
Sbjct: 110 WNPDDYGGIKVIRVPSDSVWTPDIVLFDNADGRFEGTSTKTVIRYNGTVTWTPPANYKSS 169
Query: 485 ISMQLDNWPXDMQTCTFKFGS 547
++ + +P D+Q C+ KFGS
Sbjct: 170 CTIDVTFFPFDLQNCSMKFGS 190
>Y08418-1|CAA69695.1| 503|Homo sapiens nicotinic acetylcholine
receptor alpha3 subunit precursor protein.
Length = 503
Score = 62.9 bits (146), Expect = 1e-09
Identities = 30/93 (32%), Positives = 50/93 (53%), Gaps = 2/93 (2%)
Frame = +2
Query: 275 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTXGDYALRARVSNNGS 448
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 85 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 144
Query: 449 VSWIKRLDISTPISMQLDNWPXDMQTCTFKFGS 547
V+WI + + + +P D Q CT KFGS
Sbjct: 145 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGS 177
>X53559-1|CAA37625.1| 474|Homo sapiens neuronal nicotinic
acetylcholine receptor alpha-3merase protein.
Length = 474
Score = 62.9 bits (146), Expect = 1e-09
Identities = 30/93 (32%), Positives = 50/93 (53%), Gaps = 2/93 (2%)
Frame = +2
Query: 275 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTXGDYALRARVSNNGS 448
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 56 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 115
Query: 449 VSWIKRLDISTPISMQLDNWPXDMQTCTFKFGS 547
V+WI + + + +P D Q CT KFGS
Sbjct: 116 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGS 148
>U62432-1|AAB40110.1| 504|Homo sapiens nicotinic acetylcholine
receptor alpha3 subunit precursor protein.
Length = 504
Score = 62.9 bits (146), Expect = 1e-09
Identities = 30/93 (32%), Positives = 50/93 (53%), Gaps = 2/93 (2%)
Frame = +2
Query: 275 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTXGDYALRARVSNNGS 448
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 86 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 145
Query: 449 VSWIKRLDISTPISMQLDNWPXDMQTCTFKFGS 547
V+WI + + + +P D Q CT KFGS
Sbjct: 146 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGS 178
>M37981-1|AAA59942.1| 503|Homo sapiens neuronal nicotinic
acetylcholine receptor protein.
Length = 503
Score = 62.9 bits (146), Expect = 1e-09
Identities = 30/93 (32%), Positives = 50/93 (53%), Gaps = 2/93 (2%)
Frame = +2
Query: 275 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTXGDYALRARVSNNGS 448
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 85 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 144
Query: 449 VSWIKRLDISTPISMQLDNWPXDMQTCTFKFGS 547
V+WI + + + +P D Q CT KFGS
Sbjct: 145 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGS 177
>BT006897-1|AAP35543.1| 505|Homo sapiens cholinergic receptor,
nicotinic, alpha polypeptide 3 protein.
Length = 505
Score = 62.9 bits (146), Expect = 1e-09
Identities = 30/93 (32%), Positives = 50/93 (53%), Gaps = 2/93 (2%)
Frame = +2
Query: 275 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTXGDYALRARVSNNGS 448
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 87 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 146
Query: 449 VSWIKRLDISTPISMQLDNWPXDMQTCTFKFGS 547
V+WI + + + +P D Q CT KFGS
Sbjct: 147 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGS 179
>BT006646-1|AAP35292.1| 489|Homo sapiens cholinergic receptor,
nicotinic, alpha polypeptide 3 protein.
Length = 489
Score = 62.9 bits (146), Expect = 1e-09
Identities = 30/93 (32%), Positives = 50/93 (53%), Gaps = 2/93 (2%)
Frame = +2
Query: 275 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTXGDYALRARVSNNGS 448
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 87 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 146
Query: 449 VSWIKRLDISTPISMQLDNWPXDMQTCTFKFGS 547
V+WI + + + +P D Q CT KFGS
Sbjct: 147 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGS 179
>BC098443-1|AAH98443.1| 504|Homo sapiens cholinergic receptor,
nicotinic, alpha 3 protein.
Length = 504
Score = 62.9 bits (146), Expect = 1e-09
Identities = 30/93 (32%), Positives = 50/93 (53%), Gaps = 2/93 (2%)
Frame = +2
Query: 275 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTXGDYALRARVSNNGS 448
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 86 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 145
Query: 449 VSWIKRLDISTPISMQLDNWPXDMQTCTFKFGS 547
V+WI + + + +P D Q CT KFGS
Sbjct: 146 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGS 178
>BC006114-1|AAH06114.1| 489|Homo sapiens CHRNA3 protein protein.
Length = 489
Score = 62.9 bits (146), Expect = 1e-09
Identities = 30/93 (32%), Positives = 50/93 (53%), Gaps = 2/93 (2%)
Frame = +2
Query: 275 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTXGDYALRARVSNNGS 448
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 87 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 146
Query: 449 VSWIKRLDISTPISMQLDNWPXDMQTCTFKFGS 547
V+WI + + + +P D Q CT KFGS
Sbjct: 147 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGS 179
>BC002996-1|AAH02996.1| 505|Homo sapiens cholinergic receptor,
nicotinic, alpha 3 protein.
Length = 505
Score = 62.9 bits (146), Expect = 1e-09
Identities = 30/93 (32%), Positives = 50/93 (53%), Gaps = 2/93 (2%)
Frame = +2
Query: 275 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTXGDYALRARVSNNGS 448
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 87 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 146
Query: 449 VSWIKRLDISTPISMQLDNWPXDMQTCTFKFGS 547
V+WI + + + +P D Q CT KFGS
Sbjct: 147 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGS 179
>BC001642-1|AAH01642.1| 505|Homo sapiens cholinergic receptor,
nicotinic, alpha 3 protein.
Length = 505
Score = 62.9 bits (146), Expect = 1e-09
Identities = 30/93 (32%), Positives = 50/93 (53%), Gaps = 2/93 (2%)
Frame = +2
Query: 275 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTXGDYALRARVSNNGS 448
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 87 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 146
Query: 449 VSWIKRLDISTPISMQLDNWPXDMQTCTFKFGS 547
V+WI + + + +P D Q CT KFGS
Sbjct: 147 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGS 179
>BC000513-1|AAH00513.1| 505|Homo sapiens cholinergic receptor,
nicotinic, alpha 3 protein.
Length = 505
Score = 62.9 bits (146), Expect = 1e-09
Identities = 30/93 (32%), Positives = 50/93 (53%), Gaps = 2/93 (2%)
Frame = +2
Query: 275 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTXGDYALRARVSNNGS 448
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 87 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 146
Query: 449 VSWIKRLDISTPISMQLDNWPXDMQTCTFKFGS 547
V+WI + + + +P D Q CT KFGS
Sbjct: 147 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGS 179
>AJ007783-1|CAA07682.1| 504|Homo sapiens nicotinic acetylcholine
receptor alpha-3 subunit protein.
Length = 504
Score = 62.9 bits (146), Expect = 1e-09
Identities = 30/93 (32%), Positives = 50/93 (53%), Gaps = 2/93 (2%)
Frame = +2
Query: 275 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTXGDYALRARVSNNGS 448
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 86 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 145
Query: 449 VSWIKRLDISTPISMQLDNWPXDMQTCTFKFGS 547
V+WI + + + +P D Q CT KFGS
Sbjct: 146 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGS 178
>AF385584-1|AAK68110.1| 489|Homo sapiens nicotinic cholinergic
receptor alpha 3 protein.
Length = 489
Score = 62.9 bits (146), Expect = 1e-09
Identities = 30/93 (32%), Positives = 50/93 (53%), Gaps = 2/93 (2%)
Frame = +2
Query: 275 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTXGDYALRARVSNNGS 448
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 81 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 140
Query: 449 VSWIKRLDISTPISMQLDNWPXDMQTCTFKFGS 547
V+WI + + + +P D Q CT KFGS
Sbjct: 141 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGS 173
>Y16282-1|CAA76155.1| 494|Homo sapiens nicotinic acetylcholine
receptor alpha6 subunit precursor protein.
Length = 494
Score = 62.1 bits (144), Expect = 2e-09
Identities = 40/154 (25%), Positives = 71/154 (46%), Gaps = 10/154 (6%)
Frame = +2
Query: 116 CENATSLSLMIDSLLATYDRDSPPDSKIVVNLTLHL-----RHANIRESESTVRIQADLQ 280
C + + L + Y++ P + +T+H + AN+ E + L+
Sbjct: 28 CVGCATEERLFHKLFSHYNQFIRPVENVSDPVTVHFEVAITQLANVDEVNQIMETNLWLR 87
Query: 281 MNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTXGDYAL----RARVSNNG 445
W D +L W+ E+ G T V ++++W+PD+VL N A GD+ + +A + NG
Sbjct: 88 HIWNDYKLRWDPMEYDGIETLRVPADKIWKPDIVLYNNAV---GDFQVEGKTKALLKYNG 144
Query: 446 SVSWIKRLDISTPISMQLDNWPXDMQTCTFKFGS 547
++W + M + +P D Q C+ KFGS
Sbjct: 145 MITWTPPAIFKSSCPMDITFFPFDHQNCSLKFGS 178
>Y16281-1|CAA76154.1| 529|Homo sapiens nicotinic acetylcholine
receptor alpha2 subunit precursor protein.
Length = 529
Score = 62.1 bits (144), Expect = 2e-09
Identities = 35/110 (31%), Positives = 56/110 (50%), Gaps = 5/110 (4%)
Frame = +2
Query: 233 NIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTXG 409
++ E + L+ W D +L WN ++G T L V SE +W PD+VL N A G
Sbjct: 97 DVDEKNQMMTTNVWLKQEWSDYKLRWNPADFGNITSLRVPSEMIWIPDIVLYNNA---DG 153
Query: 410 DYAL----RARVSNNGSVSWIKRLDISTPISMQLDNWPXDMQTCTFKFGS 547
++A+ +A + + G+V W+ + S+ + +P D Q C KFGS
Sbjct: 154 EFAVTHMTKAHLFSTGTVHWVPPAIYKSSCSIDVTFFPFDQQNCKMKFGS 203
>U62435-1|AAB40113.1| 494|Homo sapiens nicotinic acetylcholine
receptor alpha6 subunit precursor protein.
Length = 494
Score = 62.1 bits (144), Expect = 2e-09
Identities = 40/154 (25%), Positives = 71/154 (46%), Gaps = 10/154 (6%)
Frame = +2
Query: 116 CENATSLSLMIDSLLATYDRDSPPDSKIVVNLTLHL-----RHANIRESESTVRIQADLQ 280
C + + L + Y++ P + +T+H + AN+ E + L+
Sbjct: 28 CVGCATEERLFHKLFSHYNQFIRPVENVSDPVTVHFEVAITQLANVDEVNQIMETNLWLR 87
Query: 281 MNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTXGDYAL----RARVSNNG 445
W D +L W+ E+ G T V ++++W+PD+VL N A GD+ + +A + NG
Sbjct: 88 HIWNDYKLRWDPMEYDGIETLRVPADKIWKPDIVLYNNAV---GDFQVEGKTKALLKYNG 144
Query: 446 SVSWIKRLDISTPISMQLDNWPXDMQTCTFKFGS 547
++W + M + +P D Q C+ KFGS
Sbjct: 145 MITWTPPAIFKSSCPMDITFFPFDHQNCSLKFGS 178
>U62431-1|AAB40109.1| 529|Homo sapiens nicotinic acetylcholine
receptor alpha2 subunit precursor protein.
Length = 529
Score = 62.1 bits (144), Expect = 2e-09
Identities = 35/110 (31%), Positives = 56/110 (50%), Gaps = 5/110 (4%)
Frame = +2
Query: 233 NIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTXG 409
++ E + L+ W D +L WN ++G T L V SE +W PD+VL N A G
Sbjct: 97 DVDEKNQMMTTNVWLKQEWSDYKLRWNPADFGNITSLRVPSEMIWIPDIVLYNNA---DG 153
Query: 410 DYAL----RARVSNNGSVSWIKRLDISTPISMQLDNWPXDMQTCTFKFGS 547
++A+ +A + + G+V W+ + S+ + +P D Q C KFGS
Sbjct: 154 EFAVTHMTKAHLFSTGTVHWVPPAIYKSSCSIDVTFFPFDQQNCKMKFGS 203
>M83712-1|AAA58357.1| 468|Homo sapiens nicotinic receptor alpha 5
subunit protein.
Length = 468
Score = 62.1 bits (144), Expect = 2e-09
Identities = 36/141 (25%), Positives = 65/141 (46%), Gaps = 6/141 (4%)
Frame = +2
Query: 143 MIDSLLATYDRDSPP----DSKIVVNLTLHLRH-ANIRESESTVRIQADLQMNWIDKRLS 307
++ L Y+R P + KI + L + ++ E + L+ WID +L
Sbjct: 50 LLKDLFQDYERWVRPVEHLNDKIKIKFGLAISQLVDVDEKNQLMTTNVWLKQEWIDVKLR 109
Query: 308 WNAGEWG-CSTWLVSSERLWRPDVVLLNAAATTXGDYALRARVSNNGSVSWIKRLDISTP 484
WN ++G V S+ W PD+VL + A + + + NG+V+W + +
Sbjct: 110 WNPDDYGGIKVIRVPSDSSWTPDIVLFDNADGRFEGTSTKTVIRYNGTVTWTPPANYKSS 169
Query: 485 ISMQLDNWPXDMQTCTFKFGS 547
++ + +P D+Q C+ KFGS
Sbjct: 170 CTIDVTFFPFDLQNCSMKFGS 190
>BC014456-1|AAH14456.1| 494|Homo sapiens cholinergic receptor,
nicotinic, alpha 6 protein.
Length = 494
Score = 62.1 bits (144), Expect = 2e-09
Identities = 40/154 (25%), Positives = 71/154 (46%), Gaps = 10/154 (6%)
Frame = +2
Query: 116 CENATSLSLMIDSLLATYDRDSPPDSKIVVNLTLHL-----RHANIRESESTVRIQADLQ 280
C + + L + Y++ P + +T+H + AN+ E + L+
Sbjct: 28 CVGCATEERLFHKLFSHYNQFIRPVENVSDPVTVHFEVAITQLANVDEVNQIMETNLWLR 87
Query: 281 MNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTXGDYAL----RARVSNNG 445
W D +L W+ E+ G T V ++++W+PD+VL N A GD+ + +A + NG
Sbjct: 88 HIWNDYKLRWDPMEYDGIETLRVPADKIWKPDIVLYNNAV---GDFQVEGKTKALLKYNG 144
Query: 446 SVSWIKRLDISTPISMQLDNWPXDMQTCTFKFGS 547
++W + M + +P D Q C+ KFGS
Sbjct: 145 MITWTPPAIFKSSCPMDITFFPFDHQNCSLKFGS 178
>AB079251-1|BAC06855.1| 494|Homo sapiens Nicotinic acetylcholine
receptor alpha 6 protein.
Length = 494
Score = 62.1 bits (144), Expect = 2e-09
Identities = 40/154 (25%), Positives = 71/154 (46%), Gaps = 10/154 (6%)
Frame = +2
Query: 116 CENATSLSLMIDSLLATYDRDSPPDSKIVVNLTLHL-----RHANIRESESTVRIQADLQ 280
C + + L + Y++ P + +T+H + AN+ E + L+
Sbjct: 28 CVGCATEERLFHKLFSHYNQFIRPVENVSDPVTVHFEVAITQLANVDEVNQIMETNLWLR 87
Query: 281 MNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTXGDYAL----RARVSNNG 445
W D +L W+ E+ G T V ++++W+PD+VL N A GD+ + +A + NG
Sbjct: 88 HIWNDYKLRWDPMEYDGIETLRVPADKIWKPDIVLYNNAV---GDFQVEGKTKALLKYNG 144
Query: 446 SVSWIKRLDISTPISMQLDNWPXDMQTCTFKFGS 547
++W + M + +P D Q C+ KFGS
Sbjct: 145 MITWTPPAIFKSSCPMDITFFPFDHQNCSLKFGS 178
>X14830-1|CAA32939.1| 501|Homo sapiens protein ( Human mRNA for
muscle acetylcholine receptor beta-subunit. ).
Length = 501
Score = 61.7 bits (143), Expect = 3e-09
Identities = 43/122 (35%), Positives = 63/122 (51%), Gaps = 4/122 (3%)
Frame = +2
Query: 194 KIVVNLTL-HLRHANIRESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWR 367
++ V L L L N ++ E + ++ DL+ W D RLSW+ E G + +++E +W
Sbjct: 53 RVSVGLILAQLISLNEKDEEMSTKVYLDLE--WTDYRLSWDPAEHDGIDSLRITAESVWL 110
Query: 368 PDVVLLNAAATTXGDYAL--RARVSNNGSVSWIKRLDISTPISMQLDNWPXDMQTCTFKF 541
PDVVLLN D AL VS++GSV W + S+Q+ +P D Q CT F
Sbjct: 111 PDVVLLNNNDGNF-DVALDISVVVSSDGSVRWQPPGIYRSSCSIQVTYFPFDWQNCTMVF 169
Query: 542 GS 547
S
Sbjct: 170 SS 171
>BC011371-1|AAH11371.1| 501|Homo sapiens cholinergic receptor,
nicotinic, beta 1 (muscle) protein.
Length = 501
Score = 61.7 bits (143), Expect = 3e-09
Identities = 43/122 (35%), Positives = 63/122 (51%), Gaps = 4/122 (3%)
Frame = +2
Query: 194 KIVVNLTL-HLRHANIRESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWR 367
++ V L L L N ++ E + ++ DL+ W D RLSW+ E G + +++E +W
Sbjct: 53 RVSVGLILAQLISLNEKDEEMSTKVYLDLE--WTDYRLSWDPAEHDGIDSLRITAESVWL 110
Query: 368 PDVVLLNAAATTXGDYAL--RARVSNNGSVSWIKRLDISTPISMQLDNWPXDMQTCTFKF 541
PDVVLLN D AL VS++GSV W + S+Q+ +P D Q CT F
Sbjct: 111 PDVVLLNNNDGNF-DVALDISVVVSSDGSVRWQPPGIYRSSCSIQVTYFPFDWQNCTMVF 169
Query: 542 GS 547
S
Sbjct: 170 SS 171
>Y08421-1|CAA69698.1| 627|Homo sapiens nicotinic acetylcholine
receptor alpha4 subunit precursor protein.
Length = 627
Score = 60.5 bits (140), Expect = 7e-09
Identities = 42/145 (28%), Positives = 72/145 (49%), Gaps = 10/145 (6%)
Frame = +2
Query: 143 MIDSLLATYDRDSPPDSKI--VVNLTLHLRHA---NIRESESTVRIQADLQMNWIDKRLS 307
++ L + Y++ S P + I VV + L A ++ E + ++ W D +L
Sbjct: 40 LLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLR 99
Query: 308 WNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTXGDYAL----RARVSNNGSVSWIKRLD 472
W+ ++ T + + SE +WRPD+VL N A GD+A+ +A + ++G V W
Sbjct: 100 WDPADYENVTSIRIPSELIWRPDIVLYNNA---DGDFAVTHLTKAHLFHDGRVQWTPPAI 156
Query: 473 ISTPISMQLDNWPXDMQTCTFKFGS 547
+ S+ + +P D Q CT KFGS
Sbjct: 157 YKSSCSIDVTFFPFDQQNCTMKFGS 181
>X89741-1|CAA61893.1| 627|Homo sapiens neuronal acetylcholine
receptor alpha-4 subunit protein.
Length = 627
Score = 60.5 bits (140), Expect = 7e-09
Identities = 42/145 (28%), Positives = 72/145 (49%), Gaps = 10/145 (6%)
Frame = +2
Query: 143 MIDSLLATYDRDSPPDSKI--VVNLTLHLRHA---NIRESESTVRIQADLQMNWIDKRLS 307
++ L + Y++ S P + I VV + L A ++ E + ++ W D +L
Sbjct: 40 LLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLR 99
Query: 308 WNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTXGDYAL----RARVSNNGSVSWIKRLD 472
W+ ++ T + + SE +WRPD+VL N A GD+A+ +A + ++G V W
Sbjct: 100 WDPADYENVTSIRIPSELIWRPDIVLYNNA---DGDFAVTHLTKAHLFHDGRVQWTPPAI 156
Query: 473 ISTPISMQLDNWPXDMQTCTFKFGS 547
+ S+ + +P D Q CT KFGS
Sbjct: 157 YKSSCSIDVTFFPFDQQNCTMKFGS 181
>X87629-1|CAA60959.1| 602|Homo sapiens nicotinic acetylcholine
receptor protein.
Length = 602
Score = 60.5 bits (140), Expect = 7e-09
Identities = 42/145 (28%), Positives = 72/145 (49%), Gaps = 10/145 (6%)
Frame = +2
Query: 143 MIDSLLATYDRDSPPDSKI--VVNLTLHLRHA---NIRESESTVRIQADLQMNWIDKRLS 307
++ L + Y++ S P + I VV + L A ++ E + ++ W D +L
Sbjct: 15 LLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLR 74
Query: 308 WNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTXGDYAL----RARVSNNGSVSWIKRLD 472
W+ ++ T + + SE +WRPD+VL N A GD+A+ +A + ++G V W
Sbjct: 75 WDPADYENVTSIRIPSELIWRPDIVLYNNA---DGDFAVTHLTKAHLFHDGRVQWTPPAI 131
Query: 473 ISTPISMQLDNWPXDMQTCTFKFGS 547
+ S+ + +P D Q CT KFGS
Sbjct: 132 YKSSCSIDVTFFPFDQQNCTMKFGS 156
>U62433-1|AAB40111.1| 627|Homo sapiens nicotinic acetylcholine
receptor alpha4 subunit precursor protein.
Length = 627
Score = 60.5 bits (140), Expect = 7e-09
Identities = 42/145 (28%), Positives = 72/145 (49%), Gaps = 10/145 (6%)
Frame = +2
Query: 143 MIDSLLATYDRDSPPDSKI--VVNLTLHLRHA---NIRESESTVRIQADLQMNWIDKRLS 307
++ L + Y++ S P + I VV + L A ++ E + ++ W D +L
Sbjct: 40 LLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLR 99
Query: 308 WNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTXGDYAL----RARVSNNGSVSWIKRLD 472
W+ ++ T + + SE +WRPD+VL N A GD+A+ +A + ++G V W
Sbjct: 100 WDPADYENVTSIRIPSELIWRPDIVLYNNA---DGDFAVTHLTKAHLFHDGRVQWTPPAI 156
Query: 473 ISTPISMQLDNWPXDMQTCTFKFGS 547
+ S+ + +P D Q CT KFGS
Sbjct: 157 YKSSCSIDVTFFPFDQQNCTMKFGS 181
>M86383-1|AAC84176.1| 502|Homo sapiens nicotinic acetylcholine
receptor alpha 3 subunit precursor protein.
Length = 502
Score = 60.5 bits (140), Expect = 7e-09
Identities = 31/96 (32%), Positives = 52/96 (54%), Gaps = 5/96 (5%)
Frame = +2
Query: 275 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTXGDYAL----RARVSN 439
L+ W D +L WN +G + ++ V ++++W+PD+VL N A GD+ + +A +
Sbjct: 84 LKQIWNDYKLKWNPSGYGGAEFMRVPAQKIWKPDIVLYNNAV---GDFQVTTKTKALLKY 140
Query: 440 NGSVSWIKRLDISTPISMQLDNWPXDMQTCTFKFGS 547
G V+WI + + + +P D Q CT KFGS
Sbjct: 141 TGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGS 176
>L35901-1|AAA64743.1| 627|Homo sapiens nicotinic acetylcholine
receptor alpha 4 subunit protein.
Length = 627
Score = 60.5 bits (140), Expect = 7e-09
Identities = 42/145 (28%), Positives = 72/145 (49%), Gaps = 10/145 (6%)
Frame = +2
Query: 143 MIDSLLATYDRDSPPDSKI--VVNLTLHLRHA---NIRESESTVRIQADLQMNWIDKRLS 307
++ L + Y++ S P + I VV + L A ++ E + ++ W D +L
Sbjct: 40 LLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLR 99
Query: 308 WNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTXGDYAL----RARVSNNGSVSWIKRLD 472
W+ ++ T + + SE +WRPD+VL N A GD+A+ +A + ++G V W
Sbjct: 100 WDPADYENVTSIRIPSELIWRPDIVLYNNA---DGDFAVTHLTKAHLFHDGRVQWTPPAI 156
Query: 473 ISTPISMQLDNWPXDMQTCTFKFGS 547
+ S+ + +P D Q CT KFGS
Sbjct: 157 YKSSCSIDVTFFPFDQQNCTMKFGS 181
>DQ093071-1|AAY88737.1| 627|Homo sapiens cholinergic receptor,
nicotinic, alpha polypeptide 4 protein.
Length = 627
Score = 60.5 bits (140), Expect = 7e-09
Identities = 42/145 (28%), Positives = 72/145 (49%), Gaps = 10/145 (6%)
Frame = +2
Query: 143 MIDSLLATYDRDSPPDSKI--VVNLTLHLRHA---NIRESESTVRIQADLQMNWIDKRLS 307
++ L + Y++ S P + I VV + L A ++ E + ++ W D +L
Sbjct: 40 LLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLR 99
Query: 308 WNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTXGDYAL----RARVSNNGSVSWIKRLD 472
W+ ++ T + + SE +WRPD+VL N A GD+A+ +A + ++G V W
Sbjct: 100 WDPADYENVTSIRIPSELIWRPDIVLYNNA---DGDFAVTHLTKAHLFHDGRVQWTPPAI 156
Query: 473 ISTPISMQLDNWPXDMQTCTFKFGS 547
+ S+ + +P D Q CT KFGS
Sbjct: 157 YKSSCSIDVTFFPFDQQNCTMKFGS 181
>BC096290-1|AAH96290.1| 627|Homo sapiens cholinergic receptor,
nicotinic, alpha 4 protein.
Length = 627
Score = 60.5 bits (140), Expect = 7e-09
Identities = 42/145 (28%), Positives = 72/145 (49%), Gaps = 10/145 (6%)
Frame = +2
Query: 143 MIDSLLATYDRDSPPDSKI--VVNLTLHLRHA---NIRESESTVRIQADLQMNWIDKRLS 307
++ L + Y++ S P + I VV + L A ++ E + ++ W D +L
Sbjct: 40 LLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLR 99
Query: 308 WNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTXGDYAL----RARVSNNGSVSWIKRLD 472
W+ ++ T + + SE +WRPD+VL N A GD+A+ +A + ++G V W
Sbjct: 100 WDPADYENVTSIRIPSELIWRPDIVLYNNA---DGDFAVTHLTKAHLFHDGRVQWTPPAI 156
Query: 473 ISTPISMQLDNWPXDMQTCTFKFGS 547
+ S+ + +P D Q CT KFGS
Sbjct: 157 YKSSCSIDVTFFPFDQQNCTMKFGS 181
>BC023553-1|AAH23553.1| 501|Homo sapiens cholinergic receptor,
nicotinic, beta 1 (muscle) protein.
Length = 501
Score = 60.5 bits (140), Expect = 7e-09
Identities = 41/124 (33%), Positives = 64/124 (51%), Gaps = 6/124 (4%)
Frame = +2
Query: 194 KIVVNLTL-HLRHANIRESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWR 367
++ V L L L N ++ E + ++ DL+ W D RLSW+ E G + +++E +W
Sbjct: 53 RVSVGLILAQLISLNEKDEEMSTKVYLDLE--WTDYRLSWDPAEHDGIDSLRITAESVWL 110
Query: 368 PDVVLLNAAATTXGDY----ALRARVSNNGSVSWIKRLDISTPISMQLDNWPXDMQTCTF 535
PDVVLLN G++ + VS++GSV W + S+Q+ +P D Q CT
Sbjct: 111 PDVVLLN---NNDGNFYVALDISVVVSSDGSVRWQPPGIYRSSCSIQVTYFPFDWQNCTM 167
Query: 536 KFGS 547
F S
Sbjct: 168 VFSS 171
>Y00762-1|CAA68731.1| 457|Homo sapiens protein ( Human mRNA for
muscle acetylcholine receptor alpha-subunit. ).
Length = 457
Score = 60.1 bits (139), Expect = 1e-08
Identities = 34/123 (27%), Positives = 61/123 (49%), Gaps = 5/123 (4%)
Frame = +2
Query: 194 KIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRP 370
++ V L L ++ N+ E V L+ W+D L WN ++G + + SE++WRP
Sbjct: 50 EVTVGLQL-IQLINVDEVNQIVTTNVRLKQQWVDYNLKWNPDDYGGVKKIHIPSEKIWRP 108
Query: 371 DVVLLNAAATTXGDYAL----RARVSNNGSVSWIKRLDISTPISMQLDNWPXDMQTCTFK 538
D+VL N A GD+A+ + + G ++W + + + ++P D Q C+ K
Sbjct: 109 DLVLYNNA---DGDFAIVKFTKVLLQYTGHITWTPPAIFKSYCEIIVTHFPFDEQNCSMK 165
Query: 539 FGS 547
G+
Sbjct: 166 LGT 168
>X02502-1|CAA26344.1| 457|Homo sapiens acetylcholine receptor
protein.
Length = 457
Score = 60.1 bits (139), Expect = 1e-08
Identities = 34/123 (27%), Positives = 61/123 (49%), Gaps = 5/123 (4%)
Frame = +2
Query: 194 KIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRP 370
++ V L L ++ N+ E V L+ W+D L WN ++G + + SE++WRP
Sbjct: 50 EVTVGLQL-IQLINVDEVNQIVTTNVRLKQQWVDYNLKWNPDDYGGVKKIHIPSEKIWRP 108
Query: 371 DVVLLNAAATTXGDYAL----RARVSNNGSVSWIKRLDISTPISMQLDNWPXDMQTCTFK 538
D+VL N A GD+A+ + + G ++W + + + ++P D Q C+ K
Sbjct: 109 DLVLYNNA---DGDFAIVKFTKVLLQYTGHITWTPPAIFKSYCEIIVTHFPFDEQNCSMK 165
Query: 539 FGS 547
G+
Sbjct: 166 LGT 168
>S77094-1|AAD14247.1| 457|Homo sapiens nicotinic acetylcholine
receptor alpha subunit|AChR protein.
Length = 457
Score = 60.1 bits (139), Expect = 1e-08
Identities = 34/123 (27%), Positives = 61/123 (49%), Gaps = 5/123 (4%)
Frame = +2
Query: 194 KIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRP 370
++ V L L ++ N+ E V L+ W+D L WN ++G + + SE++WRP
Sbjct: 50 EVTVGLQL-IQLINVDEVNQIVTTNVRLKQQWVDYNLKWNPDDYGGVKKIHIPSEKIWRP 108
Query: 371 DVVLLNAAATTXGDYAL----RARVSNNGSVSWIKRLDISTPISMQLDNWPXDMQTCTFK 538
D+VL N A GD+A+ + + G ++W + + + ++P D Q C+ K
Sbjct: 109 DLVLYNNA---DGDFAIVKFTKVLLQYTGHITWTPPAIFKSYCEIIVTHFPFDEQNCSMK 165
Query: 539 FGS 547
G+
Sbjct: 166 LGT 168
>BC006314-1|AAH06314.1| 269|Homo sapiens CHRNA1 protein protein.
Length = 269
Score = 60.1 bits (139), Expect = 1e-08
Identities = 34/123 (27%), Positives = 61/123 (49%), Gaps = 5/123 (4%)
Frame = +2
Query: 194 KIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRP 370
++ V L L ++ N+ E V L+ W+D L WN ++G + + SE++WRP
Sbjct: 50 EVTVGLQL-IQLINVDEVNQIVTTNVRLKQQWVDYNLKWNPDDYGGVKKIHIPSEKIWRP 108
Query: 371 DVVLLNAAATTXGDYAL----RARVSNNGSVSWIKRLDISTPISMQLDNWPXDMQTCTFK 538
D+VL N A GD+A+ + + G ++W + + + ++P D Q C+ K
Sbjct: 109 DLVLYNNA---DGDFAIVKFTKVLLQYTGHITWTPPAIFKSYCEIIVTHFPFDEQNCSMK 165
Query: 539 FGS 547
G+
Sbjct: 166 LGT 168
>AC018890-1|AAY14687.1| 457|Homo sapiens unknown protein.
Length = 457
Score = 60.1 bits (139), Expect = 1e-08
Identities = 34/123 (27%), Positives = 61/123 (49%), Gaps = 5/123 (4%)
Frame = +2
Query: 194 KIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRP 370
++ V L L ++ N+ E V L+ W+D L WN ++G + + SE++WRP
Sbjct: 50 EVTVGLQL-IQLINVDEVNQIVTTNVRLKQQWVDYNLKWNPDDYGGVKKIHIPSEKIWRP 108
Query: 371 DVVLLNAAATTXGDYAL----RARVSNNGSVSWIKRLDISTPISMQLDNWPXDMQTCTFK 538
D+VL N A GD+A+ + + G ++W + + + ++P D Q C+ K
Sbjct: 109 DLVLYNNA---DGDFAIVKFTKVLLQYTGHITWTPPAIFKSYCEIIVTHFPFDEQNCSMK 165
Query: 539 FGS 547
G+
Sbjct: 166 LGT 168
>Y08415-1|CAA69692.1| 502|Homo sapiens nicotinic acetylcholine
receptor beta2 subunit precursor protein.
Length = 502
Score = 56.4 bits (130), Expect = 1e-07
Identities = 35/120 (29%), Positives = 55/120 (45%), Gaps = 3/120 (2%)
Frame = +2
Query: 197 IVVNLTLHLRHA-NIRESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 370
+ V L + L ++ E E + L W D RL+W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 371 DVVLLNAA-ATTXGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPXDMQTCTFKFGS 547
DVVL N A + A VS +GS+ W+ + +++ ++P D Q CT KF S
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRS 175
>X53179-1|CAA37320.1| 502|Homo sapiens precursor peptide (AA -25 to
477) protein.
Length = 502
Score = 56.4 bits (130), Expect = 1e-07
Identities = 35/120 (29%), Positives = 55/120 (45%), Gaps = 3/120 (2%)
Frame = +2
Query: 197 IVVNLTLHLRHA-NIRESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 370
+ V L + L ++ E E + L W D RL+W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 371 DVVLLNAA-ATTXGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPXDMQTCTFKFGS 547
DVVL N A + A VS +GS+ W+ + +++ ++P D Q CT KF S
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRS 175
>X01715-1|CAA25861.1| 520|Homo sapiens acetylcholine receptor gamma
chain precursor protein.
Length = 520
Score = 56.4 bits (130), Expect = 1e-07
Identities = 41/143 (28%), Positives = 66/143 (46%), Gaps = 8/143 (5%)
Frame = +2
Query: 143 MIDSLLATYDRDSPPDSKI--VVNLTLHLRHANI---RESESTVRIQADLQMNWIDKRLS 307
++ L+ YD + P + VVN++L L N+ E E + ++M W D RL
Sbjct: 32 LLADLMQNYDPNLRPAERDSDVVNVSLKLTLTNLISLNEREEALTTNVWIEMQWCDYRLR 91
Query: 308 WNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTXGDYALRARV--SNNGSVSWIKRLDIS 478
W+ ++ G V S +WRPD+VL N + AL V S +G + W+
Sbjct: 92 WDPRDYEGLWVLRVPSTMVWRPDIVLENNVDGVF-EVALYCNVLVSPDGCIYWLPPAIFR 150
Query: 479 TPISMQLDNWPXDMQTCTFKFGS 547
+ S+ + +P D Q C+ F S
Sbjct: 151 SACSISVTYFPFDWQNCSLIFQS 173
>U62437-1|AAB40115.1| 502|Homo sapiens nicotinic acetylcholine
receptor beta2 subunit precursor protein.
Length = 502
Score = 56.4 bits (130), Expect = 1e-07
Identities = 35/120 (29%), Positives = 55/120 (45%), Gaps = 3/120 (2%)
Frame = +2
Query: 197 IVVNLTLHLRHA-NIRESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 370
+ V L + L ++ E E + L W D RL+W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 371 DVVLLNAA-ATTXGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPXDMQTCTFKFGS 547
DVVL N A + A VS +GS+ W+ + +++ ++P D Q CT KF S
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRS 175
>BC075041-1|AAH75041.1| 502|Homo sapiens cholinergic receptor,
nicotinic, beta 2 (neuronal) protein.
Length = 502
Score = 56.4 bits (130), Expect = 1e-07
Identities = 35/120 (29%), Positives = 55/120 (45%), Gaps = 3/120 (2%)
Frame = +2
Query: 197 IVVNLTLHLRHA-NIRESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 370
+ V L + L ++ E E + L W D RL+W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 371 DVVLLNAA-ATTXGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPXDMQTCTFKFGS 547
DVVL N A + A VS +GS+ W+ + +++ ++P D Q CT KF S
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRS 175
>BC075040-1|AAH75040.1| 502|Homo sapiens cholinergic receptor,
nicotinic, beta 2 (neuronal) protein.
Length = 502
Score = 56.4 bits (130), Expect = 1e-07
Identities = 35/120 (29%), Positives = 55/120 (45%), Gaps = 3/120 (2%)
Frame = +2
Query: 197 IVVNLTLHLRHA-NIRESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 370
+ V L + L ++ E E + L W D RL+W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 371 DVVLLNAA-ATTXGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPXDMQTCTFKFGS 547
DVVL N A + A VS +GS+ W+ + +++ ++P D Q CT KF S
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRS 175
>AL592078-3|CAI16184.1| 502|Homo sapiens cholinergic receptor,
nicotinic, beta 2 (neuronal) protein.
Length = 502
Score = 56.4 bits (130), Expect = 1e-07
Identities = 35/120 (29%), Positives = 55/120 (45%), Gaps = 3/120 (2%)
Frame = +2
Query: 197 IVVNLTLHLRHA-NIRESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 370
+ V L + L ++ E E + L W D RL+W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 371 DVVLLNAA-ATTXGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPXDMQTCTFKFGS 547
DVVL N A + A VS +GS+ W+ + +++ ++P D Q CT KF S
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRS 175
>AJ001935-1|CAA05108.1| 504|Homo sapiens CHRNB2 protein.
Length = 504
Score = 56.4 bits (130), Expect = 1e-07
Identities = 35/120 (29%), Positives = 55/120 (45%), Gaps = 3/120 (2%)
Frame = +2
Query: 197 IVVNLTLHLRHA-NIRESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 370
+ V L + L ++ E E + L W D RL+W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 371 DVVLLNAA-ATTXGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPXDMQTCTFKFGS 547
DVVL N A + A VS +GS+ W+ + +++ ++P D Q CT KF S
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRS 175
>AF077186-1|AAD45422.1| 502|Homo sapiens neuronal nicotinic
acetylcholine receptor beta 2 protein.
Length = 502
Score = 56.4 bits (130), Expect = 1e-07
Identities = 35/120 (29%), Positives = 55/120 (45%), Gaps = 3/120 (2%)
Frame = +2
Query: 197 IVVNLTLHLRHA-NIRESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 370
+ V L + L ++ E E + L W D RL+W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 371 DVVLLNAA-ATTXGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPXDMQTCTFKFGS 547
DVVL N A + A VS +GS+ W+ + +++ ++P D Q CT KF S
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRS 175
>AC092165-3|AAY24103.1| 520|Homo sapiens unknown protein.
Length = 520
Score = 56.4 bits (130), Expect = 1e-07
Identities = 41/143 (28%), Positives = 66/143 (46%), Gaps = 8/143 (5%)
Frame = +2
Query: 143 MIDSLLATYDRDSPPDSKI--VVNLTLHLRHANI---RESESTVRIQADLQMNWIDKRLS 307
++ L+ YD + P + VVN++L L N+ E E + ++M W D RL
Sbjct: 32 LLADLMQNYDPNLRPAERDSDVVNVSLKLTLTNLISLNEREEALTTNVWIEMQWCDYRLR 91
Query: 308 WNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTXGDYALRARV--SNNGSVSWIKRLDIS 478
W+ ++ G V S +WRPD+VL N + AL V S +G + W+
Sbjct: 92 WDPRDYEGLWVLRVPSTMVWRPDIVLENNVDGVF-EVALYCNVLVSPDGCIYWLPPAIFR 150
Query: 479 TPISMQLDNWPXDMQTCTFKFGS 547
+ S+ + +P D Q C+ F S
Sbjct: 151 SACSISVTYFPFDWQNCSLIFQS 173
>X55019-1|CAA38759.1| 517|Homo sapiens acetylcholine receptor delta
subunit protein.
Length = 517
Score = 56.0 bits (129), Expect = 2e-07
Identities = 34/123 (27%), Positives = 58/123 (47%), Gaps = 3/123 (2%)
Frame = +2
Query: 188 DSKIVVNLTLHLRHA-NIRESESTVRIQADLQMNWIDKRLSWNAGEWG-CSTWLVSSERL 361
+ + V L L L + +++E E T+ ++ W D RL WNA E+G S + + +
Sbjct: 49 EESVDVALALTLSNLISLKEVEETLTTNVWIEHGWTDNRLKWNAEEFGNISVLRLPPDMV 108
Query: 362 WRPDVVL-LNAAATTXGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPXDMQTCTFK 538
W P++VL N + Y+ V + G V W+ + + + +P D Q C+ K
Sbjct: 109 WLPEIVLENNNDGSFQISYSCNVLVYHYGFVYWLPPAIFRSSCPISVTYFPFDWQNCSLK 168
Query: 539 FGS 547
F S
Sbjct: 169 FSS 171
>BC093925-1|AAH93925.1| 517|Homo sapiens cholinergic receptor,
nicotinic, delta protein.
Length = 517
Score = 56.0 bits (129), Expect = 2e-07
Identities = 34/123 (27%), Positives = 58/123 (47%), Gaps = 3/123 (2%)
Frame = +2
Query: 188 DSKIVVNLTLHLRHA-NIRESESTVRIQADLQMNWIDKRLSWNAGEWG-CSTWLVSSERL 361
+ + V L L L + +++E E T+ ++ W D RL WNA E+G S + + +
Sbjct: 49 EESVDVALALTLSNLISLKEVEETLTTNVWIEHGWTDNRLKWNAEEFGNISVLRLPPDMV 108
Query: 362 WRPDVVL-LNAAATTXGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPXDMQTCTFK 538
W P++VL N + Y+ V + G V W+ + + + +P D Q C+ K
Sbjct: 109 WLPEIVLENNNDGSFQISYSCNVLVYHYGFVYWLPPAIFRSSCPISVTYFPFDWQNCSLK 168
Query: 539 FGS 547
F S
Sbjct: 169 FSS 171
>BC093923-1|AAH93923.1| 517|Homo sapiens cholinergic receptor,
nicotinic, delta protein.
Length = 517
Score = 56.0 bits (129), Expect = 2e-07
Identities = 34/123 (27%), Positives = 58/123 (47%), Gaps = 3/123 (2%)
Frame = +2
Query: 188 DSKIVVNLTLHLRHA-NIRESESTVRIQADLQMNWIDKRLSWNAGEWG-CSTWLVSSERL 361
+ + V L L L + +++E E T+ ++ W D RL WNA E+G S + + +
Sbjct: 49 EESVDVALALTLSNLISLKEVEETLTTNVWIEHGWTDNRLKWNAEEFGNISVLRLPPDMV 108
Query: 362 WRPDVVL-LNAAATTXGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPXDMQTCTFK 538
W P++VL N + Y+ V + G V W+ + + + +P D Q C+ K
Sbjct: 109 WLPEIVLENNNDGSFQISYSCNVLVYHYGFVYWLPPAIFRSSCPISVTYFPFDWQNCSLK 168
Query: 539 FGS 547
F S
Sbjct: 169 FSS 171
>AC092165-2|AAY24102.1| 517|Homo sapiens unknown protein.
Length = 517
Score = 56.0 bits (129), Expect = 2e-07
Identities = 34/123 (27%), Positives = 58/123 (47%), Gaps = 3/123 (2%)
Frame = +2
Query: 188 DSKIVVNLTLHLRHA-NIRESESTVRIQADLQMNWIDKRLSWNAGEWG-CSTWLVSSERL 361
+ + V L L L + +++E E T+ ++ W D RL WNA E+G S + + +
Sbjct: 49 EESVDVALALTLSNLISLKEVEETLTTNVWIEHGWTDNRLKWNAEEFGNISVLRLPPDMV 108
Query: 362 WRPDVVL-LNAAATTXGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPXDMQTCTFK 538
W P++VL N + Y+ V + G V W+ + + + +P D Q C+ K
Sbjct: 109 WLPEIVLENNNDGSFQISYSCNVLVYHYGFVYWLPPAIFRSSCPISVTYFPFDWQNCSLK 168
Query: 539 FGS 547
F S
Sbjct: 169 FSS 171
>X66403-1|CAA47030.1| 493|Homo sapiens acetylcholine receptor
epsilon subunit CHRNE protein.
Length = 493
Score = 55.2 bits (127), Expect = 3e-07
Identities = 33/124 (26%), Positives = 62/124 (50%), Gaps = 3/124 (2%)
Frame = +2
Query: 185 PDSKIVVNLTLHLRHA-NIRESESTVRIQADLQMNWIDKRLSWNAGEWG-CSTWLVSSER 358
P+ + ++L + L + ++ E E T+ + ++W D RL+++ ++G T V SE
Sbjct: 45 PEDTVTISLKVTLTNLISLNEKEETLTTSVWIGIDWQDYRLNYSKDDFGGIETLRVPSEL 104
Query: 359 LWRPDVVLLNAAATTXG-DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPXDMQTCTF 535
+W P++VL N G Y V GSV+W+ + ++++ +P D Q C+
Sbjct: 105 VWLPEIVLENNIDGQFGVAYDANVLVYEGGSVTWLPPAIYRSVCAVEVTYFPFDWQNCSL 164
Query: 536 KFGS 547
F S
Sbjct: 165 IFRS 168
>AF105999-1|AAD24503.1| 493|Homo sapiens acetylcholine receptor
epsilon subunit protein.
Length = 493
Score = 55.2 bits (127), Expect = 3e-07
Identities = 33/124 (26%), Positives = 62/124 (50%), Gaps = 3/124 (2%)
Frame = +2
Query: 185 PDSKIVVNLTLHLRHA-NIRESESTVRIQADLQMNWIDKRLSWNAGEWG-CSTWLVSSER 358
P+ + ++L + L + ++ E E T+ + ++W D RL+++ ++G T V SE
Sbjct: 45 PEDTVTISLKVTLTNLISLNEKEETLTTSVWIGIDWQDYRLNYSKDDFGGIETLRVPSEL 104
Query: 359 LWRPDVVLLNAAATTXG-DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPXDMQTCTF 535
+W P++VL N G Y V GSV+W+ + ++++ +P D Q C+
Sbjct: 105 VWLPEIVLENNIDGQFGVAYDANVLVYEGGSVTWLPPAIYRSVCAVEVTYFPFDWQNCSL 164
Query: 536 KFGS 547
F S
Sbjct: 165 IFRS 168
>Z23141-1|CAA80672.1| 479|Homo sapiens cholinergic receptor,
nicotinic, alpha polypeptide 7 protein.
Length = 479
Score = 53.2 bits (122), Expect = 1e-06
Identities = 34/126 (26%), Positives = 61/126 (48%), Gaps = 2/126 (1%)
Frame = +2
Query: 176 DSPPDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSS 352
DS P + + +L+L L+ ++ E + LQM+W D L WN E+ G T
Sbjct: 24 DSQPLT-VYFSLSL-LQIMDVDEKNQVLTTNIWLQMSWTDHYLQWNVSEYPGVKTVRFPD 81
Query: 353 ERLWRPDVVLLNAA-ATTXGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPXDMQTC 529
++W+PD++L N+A + V+++G ++ + + + +P D+Q C
Sbjct: 82 GQIWKPDILLYNSADERFDATFHTNVLVNSSGHCQYLPPGIFKSSCYIDVRWFPFDVQHC 141
Query: 530 TFKFGS 547
KFGS
Sbjct: 142 KLKFGS 147
>Y08420-1|CAA69697.1| 502|Homo sapiens nicotinic acetylcholine
receptor alpha7 subunit precursor protein.
Length = 502
Score = 53.2 bits (122), Expect = 1e-06
Identities = 34/126 (26%), Positives = 61/126 (48%), Gaps = 2/126 (1%)
Frame = +2
Query: 176 DSPPDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSS 352
DS P + + +L+L L+ ++ E + LQM+W D L WN E+ G T
Sbjct: 47 DSQPLT-VYFSLSL-LQIMDVDEKNQVLTTNIWLQMSWTDHYLQWNVSEYPGVKTVRFPD 104
Query: 353 ERLWRPDVVLLNAA-ATTXGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPXDMQTC 529
++W+PD++L N+A + V+++G ++ + + + +P D+Q C
Sbjct: 105 GQIWKPDILLYNSADERFDATFHTNVLVNSSGHCQYLPPGIFKSSCYIDVRWFPFDVQHC 164
Query: 530 TFKFGS 547
KFGS
Sbjct: 165 KLKFGS 170
>X70297-1|CAA49778.1| 502|Homo sapiens neuronal nicotinic
acetylocholine receptor alpha-7 subunit protein.
Length = 502
Score = 53.2 bits (122), Expect = 1e-06
Identities = 34/126 (26%), Positives = 61/126 (48%), Gaps = 2/126 (1%)
Frame = +2
Query: 176 DSPPDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSS 352
DS P + + +L+L L+ ++ E + LQM+W D L WN E+ G T
Sbjct: 47 DSQPLT-VYFSLSL-LQIMDVDEKNQVLTTNIWLQMSWTDHYLQWNVSEYPGVKTVRFPD 104
Query: 353 ERLWRPDVVLLNAA-ATTXGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPXDMQTC 529
++W+PD++L N+A + V+++G ++ + + + +P D+Q C
Sbjct: 105 GQIWKPDILLYNSADERFDATFHTNVLVNSSGHCQYLPPGIFKSSCYIDVRWFPFDVQHC 164
Query: 530 TFKFGS 547
KFGS
Sbjct: 165 KLKFGS 170
>U62436-1|AAB40114.1| 502|Homo sapiens nicotinic acetylcholine
receptor alpha7 subunit precursor protein.
Length = 502
Score = 53.2 bits (122), Expect = 1e-06
Identities = 34/126 (26%), Positives = 61/126 (48%), Gaps = 2/126 (1%)
Frame = +2
Query: 176 DSPPDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSS 352
DS P + + +L+L L+ ++ E + LQM+W D L WN E+ G T
Sbjct: 47 DSQPLT-VYFSLSL-LQIMDVDEKNQVLTTNIWLQMSWTDHYLQWNVSEYPGVKTVRFPD 104
Query: 353 ERLWRPDVVLLNAA-ATTXGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPXDMQTC 529
++W+PD++L N+A + V+++G ++ + + + +P D+Q C
Sbjct: 105 GQIWKPDILLYNSADERFDATFHTNVLVNSSGHCQYLPPGIFKSSCYIDVRWFPFDVQHC 164
Query: 530 TFKFGS 547
KFGS
Sbjct: 165 KLKFGS 170
>DQ644022-1|ABG35128.1| 456|Homo sapiens 5-HT3 receptor subunit E
splice variant HTR3Ea protein.
Length = 456
Score = 53.2 bits (122), Expect = 1e-06
Identities = 26/92 (28%), Positives = 46/92 (50%), Gaps = 1/92 (1%)
Frame = +2
Query: 275 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTXGDYALRARVSNNGSV 451
L+M W + +SWN E G + ++++ LW PD+ ++ L A VSN G +
Sbjct: 91 LEMVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEGRI 150
Query: 452 SWIKRLDISTPISMQLDNWPXDMQTCTFKFGS 547
+ K + + + ++ + +P D Q CT F S
Sbjct: 151 RYKKPMKVDSICNLDIFYFPFDQQNCTLTFSS 182
>BC101185-1|AAI01186.1| 374|Homo sapiens HTR3E protein protein.
Length = 374
Score = 53.2 bits (122), Expect = 1e-06
Identities = 26/92 (28%), Positives = 46/92 (50%), Gaps = 1/92 (1%)
Frame = +2
Query: 275 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTXGDYALRARVSNNGSV 451
L+M W + +SWN E G + ++++ LW PD+ ++ L A VSN G +
Sbjct: 20 LEMVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEGRI 79
Query: 452 SWIKRLDISTPISMQLDNWPXDMQTCTFKFGS 547
+ K + + + ++ + +P D Q CT F S
Sbjct: 80 RYKKPMKVDSICNLDIFYFPFDQQNCTLTFSS 111
>BC101183-1|AAI01184.1| 471|Homo sapiens 5-hydroxytryptamine
(serotonin) receptor 3, family member E protein.
Length = 471
Score = 53.2 bits (122), Expect = 1e-06
Identities = 26/92 (28%), Positives = 46/92 (50%), Gaps = 1/92 (1%)
Frame = +2
Query: 275 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTXGDYALRARVSNNGSV 451
L+M W + +SWN E G + ++++ LW PD+ ++ L A VSN G +
Sbjct: 106 LEMVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEGRI 165
Query: 452 SWIKRLDISTPISMQLDNWPXDMQTCTFKFGS 547
+ K + + + ++ + +P D Q CT F S
Sbjct: 166 RYKKPMKVDSICNLDIFYFPFDQQNCTLTFSS 197
>BC101182-1|AAI01183.1| 471|Homo sapiens 5-hydroxytryptamine
(serotonin) receptor 3, family member E protein.
Length = 471
Score = 53.2 bits (122), Expect = 1e-06
Identities = 26/92 (28%), Positives = 46/92 (50%), Gaps = 1/92 (1%)
Frame = +2
Query: 275 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTXGDYALRARVSNNGSV 451
L+M W + +SWN E G + ++++ LW PD+ ++ L A VSN G +
Sbjct: 106 LEMVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEGRI 165
Query: 452 SWIKRLDISTPISMQLDNWPXDMQTCTFKFGS 547
+ K + + + ++ + +P D Q CT F S
Sbjct: 166 RYKKPMKVDSICNLDIFYFPFDQQNCTLTFSS 197
>AY159813-1|AAO38167.2| 471|Homo sapiens 5-hydroxytryptamine
serotonin receptor 3E protein.
Length = 471
Score = 53.2 bits (122), Expect = 1e-06
Identities = 26/92 (28%), Positives = 46/92 (50%), Gaps = 1/92 (1%)
Frame = +2
Query: 275 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTXGDYALRARVSNNGSV 451
L+M W + +SWN E G + ++++ LW PD+ ++ L A VSN G +
Sbjct: 106 LEMVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEGRI 165
Query: 452 SWIKRLDISTPISMQLDNWPXDMQTCTFKFGS 547
+ K + + + ++ + +P D Q CT F S
Sbjct: 166 RYKKPMKVDSICNLDIFYFPFDQQNCTLTFSS 197
>AJ586911-1|CAE52911.1| 502|Homo sapiens nicotinic acetylcholine
alpha-7 subunit protein.
Length = 502
Score = 53.2 bits (122), Expect = 1e-06
Identities = 34/126 (26%), Positives = 61/126 (48%), Gaps = 2/126 (1%)
Frame = +2
Query: 176 DSPPDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSS 352
DS P + + +L+L L+ ++ E + LQM+W D L WN E+ G T
Sbjct: 47 DSQPLT-VYFSLSL-LQIMDVDEKNQVLTTNIWLQMSWTDHYLQWNVSEYPGVKTVRFPD 104
Query: 353 ERLWRPDVVLLNAA-ATTXGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPXDMQTC 529
++W+PD++L N+A + V+++G ++ + + + +P D+Q C
Sbjct: 105 GQIWKPDILLYNSADERFDATFHTNVLVNSSGHCQYLPPGIFKSSCYIDVRWFPFDVQHC 164
Query: 530 TFKFGS 547
KFGS
Sbjct: 165 KLKFGS 170
>AJ295237-1|CAC16144.1| 450|Homo sapiens neuronal nicotinic
acetylcholine receptor subunit4 protein.
Length = 450
Score = 52.8 bits (121), Expect = 1e-06
Identities = 43/156 (27%), Positives = 67/156 (42%), Gaps = 10/156 (6%)
Frame = +2
Query: 110 AEC---ENATSLSLMIDSLLATYDRDSPP--DSKIVVNLTLHLRHANI---RESESTVRI 265
AEC E +L L D L A Y P D+ +N+TL + + I E + +
Sbjct: 20 AECLGAEGRLALKLFRD-LFANYTSALRPVADTDQTLNVTLEVTLSQIIDMDERNQVLTL 78
Query: 266 QADLQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLLNAA-ATTXGDYALRARVSN 439
++ W D L W+ +G + S +WRPD+VL N A A G + + +
Sbjct: 79 YLWIRQEWTDAYLRWDPNAYGGLDAIRIPSSLVWRPDIVLYNKADAQPPGSASTNVVLRH 138
Query: 440 NGSVSWIKRLDISTPISMQLDNWPXDMQTCTFKFGS 547
+G+V W + + + +P D Q C FGS
Sbjct: 139 DGAVRWDAPAITRSSCRVDVAAFPFDAQHCGLTFGS 174
>AJ278118-1|CAC20435.1| 450|Homo sapiens neuronal nicotinic
acetylcholine alpha10 subunit protein.
Length = 450
Score = 52.8 bits (121), Expect = 1e-06
Identities = 43/156 (27%), Positives = 67/156 (42%), Gaps = 10/156 (6%)
Frame = +2
Query: 110 AEC---ENATSLSLMIDSLLATYDRDSPP--DSKIVVNLTLHLRHANI---RESESTVRI 265
AEC E +L L D L A Y P D+ +N+TL + + I E + +
Sbjct: 20 AECLGAEGRLALKLFRD-LFANYTSALRPVADTDQTLNVTLEVTLSQIIDMDERNQVLTL 78
Query: 266 QADLQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLLNAA-ATTXGDYALRARVSN 439
++ W D L W+ +G + S +WRPD+VL N A A G + + +
Sbjct: 79 YLWIRQEWTDAYLRWDPNAYGGLDAIRIPSSLVWRPDIVLYNKADAQPPGSASTNVVLRH 138
Query: 440 NGSVSWIKRLDISTPISMQLDNWPXDMQTCTFKFGS 547
+G+V W + + + +P D Q C FGS
Sbjct: 139 DGAVRWDAPAITRSSCRVDVAAFPFDAQHCGLTFGS 174
>AF327367-1|AAK14333.1| 450|Homo sapiens nicotinic acetylcholine
receptor subunit alpha 10 protein.
Length = 450
Score = 52.8 bits (121), Expect = 1e-06
Identities = 43/156 (27%), Positives = 67/156 (42%), Gaps = 10/156 (6%)
Frame = +2
Query: 110 AEC---ENATSLSLMIDSLLATYDRDSPP--DSKIVVNLTLHLRHANI---RESESTVRI 265
AEC E +L L D L A Y P D+ +N+TL + + I E + +
Sbjct: 20 AECLGAEGRLALKLFRD-LFANYTSALRPVADTDQTLNVTLEVTLSQIIDMDERNQVLTL 78
Query: 266 QADLQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLLNAA-ATTXGDYALRARVSN 439
++ W D L W+ +G + S +WRPD+VL N A A G + + +
Sbjct: 79 YLWIRQEWTDAYLRWDPNAYGGLDAIRIPSSLVWRPDIVLYNKADAQPPGSASTNVVLRH 138
Query: 440 NGSVSWIKRLDISTPISMQLDNWPXDMQTCTFKFGS 547
+G+V W + + + +P D Q C FGS
Sbjct: 139 DGAVRWDAPAITRSSCRVDVAAFPFDAQHCGLTFGS 174
>AF199235-1|AAG00795.2| 450|Homo sapiens nicotinic acetylcholine
receptor subunit alpha 10 protein.
Length = 450
Score = 52.8 bits (121), Expect = 1e-06
Identities = 43/156 (27%), Positives = 67/156 (42%), Gaps = 10/156 (6%)
Frame = +2
Query: 110 AEC---ENATSLSLMIDSLLATYDRDSPP--DSKIVVNLTLHLRHANI---RESESTVRI 265
AEC E +L L D L A Y P D+ +N+TL + + I E + +
Sbjct: 20 AECLGAEGRLALKLFRD-LFANYTSALRPVADTDQTLNVTLEVTLSQIIDMDERNQVLTL 78
Query: 266 QADLQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLLNAA-ATTXGDYALRARVSN 439
++ W D L W+ +G + S +WRPD+VL N A A G + + +
Sbjct: 79 YLWIRQEWTDAYLRWDPNAYGGLDAIRIPSSLVWRPDIVLYNKADAQPPGSASTNVVLRH 138
Query: 440 NGSVSWIKRLDISTPISMQLDNWPXDMQTCTFKFGS 547
+G+V W + + + +P D Q C FGS
Sbjct: 139 DGAVRWDAPAITRSSCRVDVAAFPFDAQHCGLTFGS 174
>AK122638-1|BAC85499.1| 266|Homo sapiens yte protein of 76kDa)
(LCP2). protein.
Length = 266
Score = 52.0 bits (119), Expect = 3e-06
Identities = 27/98 (27%), Positives = 45/98 (45%)
Frame = +2
Query: 275 LQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTXGDYALRARVSNNGSVS 454
L+++W+D RL+WN + E LW P + +L A D + +ARV +G V
Sbjct: 87 LRLSWLDTRLAWNTSAHPRHAITLPWESLWTPRLTILEALWVDWRDQSPQARVDQDGHVK 146
Query: 455 WIKRLDISTPISMQLDNWPXDMQTCTFKFGSTDGXXSD 568
L T + +L ++P D C+ F + +D
Sbjct: 147 LNLALTTETNCNFELLHFPRDHSNCSLSFYALSNTGAD 184
>U40583-1|AAA83561.1| 502|Homo sapiens alpha 7 neuronal nicotinic
acetylcholine receptor protein.
Length = 502
Score = 51.6 bits (118), Expect = 3e-06
Identities = 34/126 (26%), Positives = 59/126 (46%), Gaps = 2/126 (1%)
Frame = +2
Query: 176 DSPPDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSS 352
DS P + + +L L L+ ++ E + LQM+W D L WN E+ G T
Sbjct: 47 DSQPLT-VYFSLNL-LQIMDVDEKNQVLTTNIWLQMSWTDHYLQWNVSEYPGVKTVRFPD 104
Query: 353 ERLWRPDVVLLNAA-ATTXGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPXDMQTC 529
++W+PD++L N+A + V+ +G ++ + + + +P D+Q C
Sbjct: 105 GQIWKPDILLYNSADERFDATFHTNVLVNPSGHCQYLPPGIFKSSCYIDVRWFPFDVQHC 164
Query: 530 TFKFGS 547
KFGS
Sbjct: 165 KLKFGS 170
>BC131799-1|AAI31800.1| 447|Homo sapiens 5-hydroxytryptamine
(serotonin) receptor 3, family member C protein.
Length = 447
Score = 51.6 bits (118), Expect = 3e-06
Identities = 24/92 (26%), Positives = 47/92 (51%), Gaps = 1/92 (1%)
Frame = +2
Query: 275 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTXGDYALRARVSNNGSV 451
+ + W + ++WN E G + V +E LW PD+ ++ + L A +S+ G +
Sbjct: 91 MDLVWDNPFINWNPKECVGINKLTVLAENLWLPDIFIVESMDVDQTPSGLTAYISSEGRI 150
Query: 452 SWIKRLDISTPISMQLDNWPXDMQTCTFKFGS 547
+ K + +++ ++ + +P D Q CTF F S
Sbjct: 151 KYDKPMRVTSICNLDIFYFPFDQQNCTFTFSS 182
>AY349353-1|AAQ93477.1| 456|Homo sapiens 5-HT3c1 serotonin
receptor-like protein protein.
Length = 456
Score = 51.6 bits (118), Expect = 3e-06
Identities = 26/96 (27%), Positives = 47/96 (48%), Gaps = 1/96 (1%)
Frame = +2
Query: 263 IQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTXGDYALRARVSN 439
+ A L + W + +SWN E G + ++++ LW PD+ ++ L A VSN
Sbjct: 87 MSAILDVVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSN 146
Query: 440 NGSVSWIKRLDISTPISMQLDNWPXDMQTCTFKFGS 547
G + + K + + + ++ + +P D Q CT F S
Sbjct: 147 EGRIRYKKPMKVDSICNLDIFYFPFDQQNCTLTFSS 182
>AY349352-1|AAQ93476.1| 441|Homo sapiens 5-HT3c1 serotonin
receptor-like protein protein.
Length = 441
Score = 51.6 bits (118), Expect = 3e-06
Identities = 26/96 (27%), Positives = 47/96 (48%), Gaps = 1/96 (1%)
Frame = +2
Query: 263 IQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTXGDYALRARVSN 439
+ A L + W + +SWN E G + ++++ LW PD+ ++ L A VSN
Sbjct: 72 MSAILDVVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSN 131
Query: 440 NGSVSWIKRLDISTPISMQLDNWPXDMQTCTFKFGS 547
G + + K + + + ++ + +P D Q CT F S
Sbjct: 132 EGRIRYKKPMKVDSICNLDIFYFPFDQQNCTLTFSS 167
>AF385585-1|AAK68111.1| 502|Homo sapiens nicotinic cholinergic
receptor alpha 7 protein.
Length = 502
Score = 51.6 bits (118), Expect = 3e-06
Identities = 34/126 (26%), Positives = 59/126 (46%), Gaps = 2/126 (1%)
Frame = +2
Query: 176 DSPPDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSS 352
DS P + + +L L L+ ++ E + LQM+W D L WN E+ G T
Sbjct: 47 DSQPLT-VYFSLNL-LQIMDVDEKNQVLTTNIWLQMSWTDHYLQWNVSEYPGVKTVRFPD 104
Query: 353 ERLWRPDVVLLNAA-ATTXGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPXDMQTC 529
++W+PD++L N+A + V+ +G ++ + + + +P D+Q C
Sbjct: 105 GQIWKPDILLYNSADERFDATFHTNVLVNPSGHCQYLPPGIFKSSCYIDVRWFPFDVQHC 164
Query: 530 TFKFGS 547
KFGS
Sbjct: 165 KLKFGS 170
>BC110597-1|AAI10598.1| 411|Homo sapiens ligand-gated ion channel,
zinc activated 1 protein.
Length = 411
Score = 51.2 bits (117), Expect = 4e-06
Identities = 26/89 (29%), Positives = 42/89 (47%)
Frame = +2
Query: 275 LQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTXGDYALRARVSNNGSVS 454
L+++W+D RL+WN + E LW P + +L A D + +ARV +G V
Sbjct: 86 LRLSWLDTRLAWNTSAHPRHAITLPWESLWTPRLTILEALWVDWRDQSPQARVDQDGHVK 145
Query: 455 WIKRLDISTPISMQLDNWPXDMQTCTFKF 541
L T + +L ++P D C+ F
Sbjct: 146 LNLALTTETNCNFELLHFPRDHSNCSLSF 174
>AF512521-1|AAO20969.1| 411|Homo sapiens ligand-gated ion channel
subunit protein.
Length = 411
Score = 51.2 bits (117), Expect = 4e-06
Identities = 26/89 (29%), Positives = 42/89 (47%)
Frame = +2
Query: 275 LQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTXGDYALRARVSNNGSVS 454
L+++W+D RL+WN + E LW P + +L A D + +ARV +G V
Sbjct: 86 LRLSWLDTRLAWNTSAHPRHAITLPWESLWTPRLTILEALWVDWRDQSPQARVDQDGHVK 145
Query: 455 WIKRLDISTPISMQLDNWPXDMQTCTFKF 541
L T + +L ++P D C+ F
Sbjct: 146 LNLALTTETNCNFELLHFPRDHSNCSLSF 174
>AF459285-1|AAL66182.1| 447|Homo sapiens 5-hydroxytryptamine
receptor 3 subunit C protein.
Length = 447
Score = 51.2 bits (117), Expect = 4e-06
Identities = 24/92 (26%), Positives = 46/92 (50%), Gaps = 1/92 (1%)
Frame = +2
Query: 275 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTXGDYALRARVSNNGSV 451
+ + W + ++WN E G + V +E LW PD+ ++ + L A +S+ G +
Sbjct: 91 MDLVWDNPFINWNPKECVGINKLTVLAENLWLPDIFIVESMDVDQTPSGLTAYISSEGRI 150
Query: 452 SWIKRLDISTPISMQLDNWPXDMQTCTFKFGS 547
+ K + +++ + + +P D Q CTF F S
Sbjct: 151 KYDKPMRVTSICKLDIFYFPFDQQNCTFTFSS 182
>BC113575-1|AAI13576.1| 479|Homo sapiens cholinergic receptor,
nicotinic, alpha 9 protein.
Length = 479
Score = 50.8 bits (116), Expect = 6e-06
Identities = 36/154 (23%), Positives = 68/154 (44%), Gaps = 7/154 (4%)
Frame = +2
Query: 107 AAECENATSLSLMIDSLLATYDRDSPP--DSKIVVNLTLHLRHANIRESESTVRIQAD-- 274
AAE + + + L Y P D+ V+N+TL + + I++ + +I
Sbjct: 22 AAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQITLSQIKDMDERNQILTAYL 81
Query: 275 -LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTXGD-YALRARVSNNG 445
++ W D L+W+ ++ G + + S+ +WRPD+VL N A + + +G
Sbjct: 82 WIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKADDESSEPVNTNVVLRYDG 141
Query: 446 SVSWIKRLDISTPISMQLDNWPXDMQTCTFKFGS 547
++W + + + +P D Q C FGS
Sbjct: 142 LITWDAPAITKSSCVVDVTYFPFDNQQCNLTFGS 175
>BC113549-1|AAI13550.1| 479|Homo sapiens cholinergic receptor,
nicotinic, alpha 9 protein.
Length = 479
Score = 50.8 bits (116), Expect = 6e-06
Identities = 36/154 (23%), Positives = 68/154 (44%), Gaps = 7/154 (4%)
Frame = +2
Query: 107 AAECENATSLSLMIDSLLATYDRDSPP--DSKIVVNLTLHLRHANIRESESTVRIQAD-- 274
AAE + + + L Y P D+ V+N+TL + + I++ + +I
Sbjct: 22 AAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQITLSQIKDMDERNQILTAYL 81
Query: 275 -LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTXGD-YALRARVSNNG 445
++ W D L+W+ ++ G + + S+ +WRPD+VL N A + + +G
Sbjct: 82 WIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKADDESSEPVNTNVVLRYDG 141
Query: 446 SVSWIKRLDISTPISMQLDNWPXDMQTCTFKFGS 547
++W + + + +P D Q C FGS
Sbjct: 142 LITWDAPAITKSSCVVDVTYFPFDNQQCNLTFGS 175
>BC111802-1|AAI11803.1| 465|Homo sapiens CHRNG protein protein.
Length = 465
Score = 50.8 bits (116), Expect = 6e-06
Identities = 33/113 (29%), Positives = 55/113 (48%), Gaps = 7/113 (6%)
Frame = +2
Query: 143 MIDSLLATYDRDSPPDSKI--VVNLTLHLRHANI---RESESTVRIQADLQMNWIDKRLS 307
++ L+ YD + P + VVN++L L N+ E E + ++M W D RL
Sbjct: 29 LLADLMQNYDPNLRPAERDSDVVNVSLKLTLTNLISLNEREEALTTNVWIEMQWCDYRLR 88
Query: 308 WNAGEW-GCSTWLVSSERLWRPDVVLLNAAAT-TXGDYALRARVSNNGSVSWI 460
W+ ++ G V S +WRPD+VL N + T + + L+ + S+ WI
Sbjct: 89 WDPRDYEGLWVLRVPSTMVWRPDIVLENKSQTYSTNEIDLQLSQEDGQSIEWI 141
>AY123244-1|AAM74523.1| 479|Homo sapiens nicotinic acetylcholine
receptor subunit alpha 9 protein.
Length = 479
Score = 50.8 bits (116), Expect = 6e-06
Identities = 36/154 (23%), Positives = 68/154 (44%), Gaps = 7/154 (4%)
Frame = +2
Query: 107 AAECENATSLSLMIDSLLATYDRDSPP--DSKIVVNLTLHLRHANIRESESTVRIQAD-- 274
AAE + + + L Y P D+ V+N+TL + + I++ + +I
Sbjct: 22 AAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQITLSQIKDMDERNQILTAYL 81
Query: 275 -LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTXGD-YALRARVSNNG 445
++ W D L+W+ ++ G + + S+ +WRPD+VL N A + + +G
Sbjct: 82 WIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKADDESSEPVNTNVVLRYDG 141
Query: 446 SVSWIKRLDISTPISMQLDNWPXDMQTCTFKFGS 547
++W + + + +P D Q C FGS
Sbjct: 142 LITWDAPAITKSSCVVDVTYFPFDNQQCNLTFGS 175
>AJ243342-1|CAB65091.1| 479|Homo sapiens nicotinic acetylcholine
receptor alpha 9 subunit protein.
Length = 479
Score = 50.8 bits (116), Expect = 6e-06
Identities = 36/154 (23%), Positives = 68/154 (44%), Gaps = 7/154 (4%)
Frame = +2
Query: 107 AAECENATSLSLMIDSLLATYDRDSPP--DSKIVVNLTLHLRHANIRESESTVRIQAD-- 274
AAE + + + L Y P D+ V+N+TL + + I++ + +I
Sbjct: 22 AAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQITLSQIKDMDERNQILTAYL 81
Query: 275 -LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTXGD-YALRARVSNNG 445
++ W D L+W+ ++ G + + S+ +WRPD+VL N A + + +G
Sbjct: 82 WIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKADDESSEPVNTNVVLRYDG 141
Query: 446 SVSWIKRLDISTPISMQLDNWPXDMQTCTFKFGS 547
++W + + + +P D Q C FGS
Sbjct: 142 LITWDAPAITKSSCVVDVTYFPFDNQQCNLTFGS 175
>AF227732-1|AAF61920.1| 470|Homo sapiens nicotinic acetylcholine
receptor alpha 9 subunit protein.
Length = 470
Score = 50.8 bits (116), Expect = 6e-06
Identities = 36/154 (23%), Positives = 68/154 (44%), Gaps = 7/154 (4%)
Frame = +2
Query: 107 AAECENATSLSLMIDSLLATYDRDSPP--DSKIVVNLTLHLRHANIRESESTVRIQAD-- 274
AAE + + + L Y P D+ V+N+TL + + I++ + +I
Sbjct: 16 AAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQITLSQIKDMDERNQILTAYL 75
Query: 275 -LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTXGD-YALRARVSNNG 445
++ W D L+W+ ++ G + + S+ +WRPD+VL N A + + +G
Sbjct: 76 WIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKADDESSEPVNTNVVLRYDG 135
Query: 446 SVSWIKRLDISTPISMQLDNWPXDMQTCTFKFGS 547
++W + + + +P D Q C FGS
Sbjct: 136 LITWDAPAITKSSCVVDVTYFPFDNQQCNLTFGS 169
>AC118275-1|AAY40986.1| 479|Homo sapiens unknown protein.
Length = 479
Score = 50.8 bits (116), Expect = 6e-06
Identities = 36/154 (23%), Positives = 68/154 (44%), Gaps = 7/154 (4%)
Frame = +2
Query: 107 AAECENATSLSLMIDSLLATYDRDSPP--DSKIVVNLTLHLRHANIRESESTVRIQAD-- 274
AAE + + + L Y P D+ V+N+TL + + I++ + +I
Sbjct: 22 AAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQITLSQIKDMDERNQILTAYL 81
Query: 275 -LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTXGD-YALRARVSNNG 445
++ W D L+W+ ++ G + + S+ +WRPD+VL N A + + +G
Sbjct: 82 WIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKADDESSEPVNTNVVLRYDG 141
Query: 446 SVSWIKRLDISTPISMQLDNWPXDMQTCTFKFGS 547
++W + + + +P D Q C FGS
Sbjct: 142 LITWDAPAITKSSCVVDVTYFPFDNQQCNLTFGS 175
>AB223030-1|BAE19924.1| 411|Homo sapiens ligand-gated ion-channel
receptor L2 protein.
Length = 411
Score = 50.8 bits (116), Expect = 6e-06
Identities = 26/89 (29%), Positives = 42/89 (47%)
Frame = +2
Query: 275 LQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTXGDYALRARVSNNGSVS 454
L+++W+D RL+WN + E LW P + +L A D + +ARV +G V
Sbjct: 86 LRLSWLDTRLAWNTSAHPRHAITLPWESLWTPRLTILEALWVDWRDQSPQARVDQDGHVK 145
Query: 455 WIKRLDISTPISMQLDNWPXDMQTCTFKF 541
L T + +L ++P D C+ F
Sbjct: 146 LNLALATETNCNFELLHFPRDHSNCSLSF 174
>U77731-2|AAB38273.1| 360|Homo sapiens glycine receptor alpha 2B
subunit protein.
Length = 360
Score = 50.0 bits (114), Expect = 1e-05
Identities = 33/125 (26%), Positives = 55/125 (44%), Gaps = 4/125 (3%)
Frame = +2
Query: 185 PDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERL 361
P + N+ ++ +I E+ R+ L+ W D RL+++ S + +
Sbjct: 69 PPVNVTCNIFIN-SFGSIAETTMDYRVNIFLRQQWNDSRLAYSEYPDDSLDLDPSMLDSI 127
Query: 362 WRPDVVLLNAAATTXGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPXDMQTCT 532
W+PD+ N D R+S NG V + RL ++ M L N+P D+QTCT
Sbjct: 128 WKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNFPMDVQTCT 187
Query: 533 FKFGS 547
+ S
Sbjct: 188 MQLES 192
>L08485-1|AAA58490.1| 462|Homo sapiens GABA-benzodiazepine receptor
alpha-5-subunit protein.
Length = 462
Score = 50.0 bits (114), Expect = 1e-05
Identities = 36/150 (24%), Positives = 66/150 (44%), Gaps = 7/150 (4%)
Frame = +2
Query: 119 ENATSLSLMIDSLLATYDRDSPPD--SKIV-VNLTLHLRHAN-IRESESTVRIQADLQMN 286
+N T + ++D LL YD P +I V +++ + ++E I + +
Sbjct: 44 DNITIFTRILDGLLDGYDNRLRPGLGERITQVRTDIYVTSFGPVSDTEMEYTIDVFFRQS 103
Query: 287 WIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTXGDYALR---ARVSNNGSVSW 457
W D+RL + + + ++W PD N + + R+ ++G++ +
Sbjct: 104 WKDERLRFKGPMQRLPLNNLLASKIWTPDTFFHNGKKSIAHNMTTPNKLLRLEDDGTLLY 163
Query: 458 IKRLDISTPISMQLDNWPXDMQTCTFKFGS 547
RL IS MQL+++P D C KFGS
Sbjct: 164 TMRLTISAECPMQLEDFPMDAHACPLKFGS 193
>CR450343-1|CAG29339.1| 452|Homo sapiens GLRA2 protein.
Length = 452
Score = 50.0 bits (114), Expect = 1e-05
Identities = 33/125 (26%), Positives = 55/125 (44%), Gaps = 4/125 (3%)
Frame = +2
Query: 185 PDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERL 361
P + N+ ++ +I E+ R+ L+ W D RL+++ S + +
Sbjct: 69 PPVNVTCNIFIN-SFGSIAETTMDYRVNIFLRQQWNDSRLAYSEYPDDSLDLDPSMLDSI 127
Query: 362 WRPDVVLLNAAATTXGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPXDMQTCT 532
W+PD+ N D R+S NG V + RL ++ M L N+P D+QTCT
Sbjct: 128 WKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNFPMDVQTCT 187
Query: 533 FKFGS 547
+ S
Sbjct: 188 MQLES 192
>BT009830-1|AAP88832.1| 462|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 5 protein.
Length = 462
Score = 50.0 bits (114), Expect = 1e-05
Identities = 36/150 (24%), Positives = 66/150 (44%), Gaps = 7/150 (4%)
Frame = +2
Query: 119 ENATSLSLMIDSLLATYDRDSPPD--SKIV-VNLTLHLRHAN-IRESESTVRIQADLQMN 286
+N T + ++D LL YD P +I V +++ + ++E I + +
Sbjct: 44 DNITIFTRILDGLLDGYDNRLRPGLGERITQVRTDIYVTSFGPVSDTEMEYTIDVFFRQS 103
Query: 287 WIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTXGDYALR---ARVSNNGSVSW 457
W D+RL + + + ++W PD N + + R+ ++G++ +
Sbjct: 104 WKDERLRFKGPMQRLPLNNLLASKIWTPDTFFHNGKKSIAHNMTTPNKLLRLEDDGTLLY 163
Query: 458 IKRLDISTPISMQLDNWPXDMQTCTFKFGS 547
RL IS MQL+++P D C KFGS
Sbjct: 164 TMRLTISAECPMQLEDFPMDAHACPLKFGS 193
>BC113422-1|AAI13423.1| 462|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 5 protein.
Length = 462
Score = 50.0 bits (114), Expect = 1e-05
Identities = 36/150 (24%), Positives = 66/150 (44%), Gaps = 7/150 (4%)
Frame = +2
Query: 119 ENATSLSLMIDSLLATYDRDSPPD--SKIV-VNLTLHLRHAN-IRESESTVRIQADLQMN 286
+N T + ++D LL YD P +I V +++ + ++E I + +
Sbjct: 44 DNITIFTRILDGLLDGYDNRLRPGLGERITQVRTDIYVTSFGPVSDTEMEYTIDVFFRQS 103
Query: 287 WIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTXGDYALR---ARVSNNGSVSW 457
W D+RL + + + ++W PD N + + R+ ++G++ +
Sbjct: 104 WKDERLRFKGPMQRLPLNNLLASKIWTPDTFFHNGKKSIAHNMTTPNKLLRLEDDGTLLY 163
Query: 458 IKRLDISTPISMQLDNWPXDMQTCTFKFGS 547
RL IS MQL+++P D C KFGS
Sbjct: 164 TMRLTISAECPMQLEDFPMDAHACPLKFGS 193
>BC111979-1|AAI11980.1| 462|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 5, precursor protein.
Length = 462
Score = 50.0 bits (114), Expect = 1e-05
Identities = 36/150 (24%), Positives = 66/150 (44%), Gaps = 7/150 (4%)
Frame = +2
Query: 119 ENATSLSLMIDSLLATYDRDSPPD--SKIV-VNLTLHLRHAN-IRESESTVRIQADLQMN 286
+N T + ++D LL YD P +I V +++ + ++E I + +
Sbjct: 44 DNITIFTRILDGLLDGYDNRLRPGLGERITQVRTDIYVTSFGPVSDTEMEYTIDVFFRQS 103
Query: 287 WIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTXGDYALR---ARVSNNGSVSW 457
W D+RL + + + ++W PD N + + R+ ++G++ +
Sbjct: 104 WKDERLRFKGPMQRLPLNNLLASKIWTPDTFFHNGKKSIAHNMTTPNKLLRLEDDGTLLY 163
Query: 458 IKRLDISTPISMQLDNWPXDMQTCTFKFGS 547
RL IS MQL+++P D C KFGS
Sbjct: 164 TMRLTISAECPMQLEDFPMDAHACPLKFGS 193
>AY437084-1|AAR87843.1| 452|Homo sapiens glycine receptor alpha2
subunit B protein.
Length = 452
Score = 50.0 bits (114), Expect = 1e-05
Identities = 33/125 (26%), Positives = 55/125 (44%), Gaps = 4/125 (3%)
Frame = +2
Query: 185 PDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERL 361
P + N+ ++ +I E+ R+ L+ W D RL+++ S + +
Sbjct: 69 PPVNVTCNIFIN-SFGSIAETTMDYRVNIFLRQQWNDSRLAYSEYPDDSLDLDPSMLDSI 127
Query: 362 WRPDVVLLNAAATTXGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPXDMQTCT 532
W+PD+ N D R+S NG V + RL ++ M L N+P D+QTCT
Sbjct: 128 WKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNFPMDVQTCT 187
Query: 533 FKFGS 547
+ S
Sbjct: 188 MQLES 192
>X52008-1|CAA36257.1| 452|Homo sapiens inhibitory glycine receptor
protein.
Length = 452
Score = 49.6 bits (113), Expect = 1e-05
Identities = 32/125 (25%), Positives = 55/125 (44%), Gaps = 4/125 (3%)
Frame = +2
Query: 185 PDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERL 361
P + N+ ++ ++ E+ R+ L+ W D RL+++ S + +
Sbjct: 69 PPVNVTCNIFIN-SFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPDDSLDLDPSMLDSI 127
Query: 362 WRPDVVLLNAAATTXGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPXDMQTCT 532
W+PD+ N D R+S NG V + RL ++ M L N+P D+QTCT
Sbjct: 128 WKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNFPMDVQTCT 187
Query: 533 FKFGS 547
+ S
Sbjct: 188 MQLES 192
>U77731-1|AAB38272.1| 360|Homo sapiens glycine receptor alpha 2
subunit protein.
Length = 360
Score = 49.6 bits (113), Expect = 1e-05
Identities = 32/125 (25%), Positives = 55/125 (44%), Gaps = 4/125 (3%)
Frame = +2
Query: 185 PDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERL 361
P + N+ ++ ++ E+ R+ L+ W D RL+++ S + +
Sbjct: 69 PPVNVTCNIFIN-SFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPDDSLDLDPSMLDSI 127
Query: 362 WRPDVVLLNAAATTXGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPXDMQTCT 532
W+PD+ N D R+S NG V + RL ++ M L N+P D+QTCT
Sbjct: 128 WKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNFPMDVQTCT 187
Query: 533 FKFGS 547
+ S
Sbjct: 188 MQLES 192
>BC032864-1|AAH32864.1| 452|Homo sapiens glycine receptor, alpha 2
protein.
Length = 452
Score = 49.6 bits (113), Expect = 1e-05
Identities = 32/125 (25%), Positives = 55/125 (44%), Gaps = 4/125 (3%)
Frame = +2
Query: 185 PDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERL 361
P + N+ ++ ++ E+ R+ L+ W D RL+++ S + +
Sbjct: 69 PPVNVTCNIFIN-SFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPDDSLDLDPSMLDSI 127
Query: 362 WRPDVVLLNAAATTXGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPXDMQTCT 532
W+PD+ N D R+S NG V + RL ++ M L N+P D+QTCT
Sbjct: 128 WKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNFPMDVQTCT 187
Query: 533 FKFGS 547
+ S
Sbjct: 188 MQLES 192
>AY437083-1|AAR87842.1| 452|Homo sapiens glycine receptor alpha2
subunit A protein.
Length = 452
Score = 49.6 bits (113), Expect = 1e-05
Identities = 32/125 (25%), Positives = 55/125 (44%), Gaps = 4/125 (3%)
Frame = +2
Query: 185 PDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERL 361
P + N+ ++ ++ E+ R+ L+ W D RL+++ S + +
Sbjct: 69 PPVNVTCNIFIN-SFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPDDSLDLDPSMLDSI 127
Query: 362 WRPDVVLLNAAATTXGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPXDMQTCT 532
W+PD+ N D R+S NG V + RL ++ M L N+P D+QTCT
Sbjct: 128 WKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNFPMDVQTCT 187
Query: 533 FKFGS 547
+ S
Sbjct: 188 MQLES 192
>AF053495-1|AAC35290.1| 452|Homo sapiens glycine receptor alpha 2
subunit protein.
Length = 452
Score = 49.6 bits (113), Expect = 1e-05
Identities = 32/125 (25%), Positives = 55/125 (44%), Gaps = 4/125 (3%)
Frame = +2
Query: 185 PDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERL 361
P + N+ ++ ++ E+ R+ L+ W D RL+++ S + +
Sbjct: 69 PPVNVTCNIFIN-SFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPDDSLDLDPSMLDSI 127
Query: 362 WRPDVVLLNAAATTXGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPXDMQTCT 532
W+PD+ N D R+S NG V + RL ++ M L N+P D+QTCT
Sbjct: 128 WKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNFPMDVQTCT 187
Query: 533 FKFGS 547
+ S
Sbjct: 188 MQLES 192
>BC028629-1|AAH28629.1| 492|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 3 protein.
Length = 492
Score = 48.8 bits (111), Expect = 2e-05
Identities = 34/150 (22%), Positives = 65/150 (43%), Gaps = 7/150 (4%)
Frame = +2
Query: 119 ENATSLSLMIDSLLATYDRDSPP---DSKIVVNLTLHLRHAN-IRESESTVRIQADLQMN 286
+N T + ++D LL YD P D+ V +++ + +++ I +
Sbjct: 62 DNITIFTRILDRLLDGYDNRLRPGLGDAVTEVKTDIYVTSFGPVSDTDMEYTIDVFFRQT 121
Query: 287 WIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTXGDYALR---ARVSNNGSVSW 457
W D+RL ++ + + ++W PD N + + R+ +NG++ +
Sbjct: 122 WHDERLKFDGPMKILPLNNLLASKIWTPDTFFHNGKKSVAHNMTTPNKLLRLVDNGTLPY 181
Query: 458 IKRLDISTPISMQLDNWPXDMQTCTFKFGS 547
RL I M L+++P D+ C KFGS
Sbjct: 182 TMRLTIHAECPMHLEDFPMDVHACPLKFGS 211
>S62908-1|AAB27279.1| 492|Homo sapiens gamma-aminobutyric acidA
receptor alpha 3 subunit protein.
Length = 492
Score = 48.4 bits (110), Expect = 3e-05
Identities = 34/150 (22%), Positives = 65/150 (43%), Gaps = 7/150 (4%)
Frame = +2
Query: 119 ENATSLSLMIDSLLATYDRDSPP---DSKIVVNLTLHLRHAN-IRESESTVRIQADLQMN 286
+N T + ++D LL YD P D+ V +++ + +++ I +
Sbjct: 62 DNITIFTRILDRLLDGYDNRLRPGLGDAVTEVKTDIYVTSFGPVSDTDMEYTIDVFFRQT 121
Query: 287 WIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTXGDYALR---ARVSNNGSVSW 457
W D+RL ++ + + ++W PD N + + R+ +NG++ +
Sbjct: 122 WHDERLKFDGPMKILPLNNLLASKIWTPDTFFHNGKKSVAHNMTTPNKLLRLVDNGTLLY 181
Query: 458 IKRLDISTPISMQLDNWPXDMQTCTFKFGS 547
RL I M L+++P D+ C KFGS
Sbjct: 182 TMRLTIHAECPMHLEDFPMDVHACPLKFGS 211
>AF166361-1|AAG12455.1| 492|Homo sapiens GABA receptor subunit
alpha 3 protein.
Length = 492
Score = 48.4 bits (110), Expect = 3e-05
Identities = 34/150 (22%), Positives = 65/150 (43%), Gaps = 7/150 (4%)
Frame = +2
Query: 119 ENATSLSLMIDSLLATYDRDSPP---DSKIVVNLTLHLRHAN-IRESESTVRIQADLQMN 286
+N T + ++D LL YD P D+ V +++ + +++ I +
Sbjct: 62 DNITIFTRILDRLLDGYDNRLRPGLGDAVTEVKTDIYVTSFGPVSDTDMEYTIDVFFRQT 121
Query: 287 WIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTXGDYALR---ARVSNNGSVSW 457
W D+RL ++ + + ++W PD N + + R+ +NG++ +
Sbjct: 122 WHDERLKFDGPMKILPLNNLLASKIWTPDTFFHNGKKSVAHNMTTPNKLLRLVDNGTLLY 181
Query: 458 IKRLDISTPISMQLDNWPXDMQTCTFKFGS 547
RL I M L+++P D+ C KFGS
Sbjct: 182 TMRLTIHAECPMHLEDFPMDVHACPLKFGS 211
>M59216-1|AAA35862.1| 474|Homo sapiens gamma-aminobutyric acid
receptor beta-1 subunit protein.
Length = 474
Score = 48.0 bits (109), Expect = 4e-05
Identities = 40/169 (23%), Positives = 72/169 (42%), Gaps = 7/169 (4%)
Frame = +2
Query: 92 CAIASAAECENATSLSLMIDSLLATYDRDSPPD---SKIVVNLTLHLRHAN-IRESESTV 259
C S E N + + +D LL YD PD + V + + + + + E
Sbjct: 23 CCAHSTNEPSNMSYVKETVDRLLKGYDIRLRPDFGGPPVDVGMRIDVASIDMVSEVNMDY 82
Query: 260 RIQADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTXGDYALRARVSN 439
+ Q +W DKRLS++ + +++LW PD LN + ++ R+
Sbjct: 83 TLTMYFQQSWKDKRLSYSGIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIR 142
Query: 440 ---NGSVSWIKRLDISTPISMQLDNWPXDMQTCTFKFGSTDGXXSDELD 577
+G+V + R+ + M L +P D Q CT + S G +D+++
Sbjct: 143 LHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESY-GYTTDDIE 190
>S77554-1|AAB33983.1| 474|Homo sapiens GABAA receptor beta 2
subunit protein.
Length = 474
Score = 47.6 bits (108), Expect = 5e-05
Identities = 41/169 (24%), Positives = 72/169 (42%), Gaps = 7/169 (4%)
Frame = +2
Query: 92 CAIASAAECENATSLSLMIDSLLATYDRDSPPD---SKIVVNLTLHLRHAN-IRESESTV 259
CA S + N + + +D LL YD PD + V + + + + + E
Sbjct: 23 CA-QSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDIASIDMVSEVNMDY 81
Query: 260 RIQADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTXGDYALRARVSN 439
+ Q W DKRLS+N + +++LW PD LN + ++ R+
Sbjct: 82 TLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIR 141
Query: 440 ---NGSVSWIKRLDISTPISMQLDNWPXDMQTCTFKFGSTDGXXSDELD 577
+G+V + R+ + M L +P D Q CT + S G +D+++
Sbjct: 142 LHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESY-GYTTDDIE 189
>S77553-1|AAB33982.1| 512|Homo sapiens GABAA receptor beta 2
subunit protein.
Length = 512
Score = 47.6 bits (108), Expect = 5e-05
Identities = 41/169 (24%), Positives = 72/169 (42%), Gaps = 7/169 (4%)
Frame = +2
Query: 92 CAIASAAECENATSLSLMIDSLLATYDRDSPPD---SKIVVNLTLHLRHAN-IRESESTV 259
CA S + N + + +D LL YD PD + V + + + + + E
Sbjct: 23 CA-QSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDIASIDMVSEVNMDY 81
Query: 260 RIQADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTXGDYALRARVSN 439
+ Q W DKRLS+N + +++LW PD LN + ++ R+
Sbjct: 82 TLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIR 141
Query: 440 ---NGSVSWIKRLDISTPISMQLDNWPXDMQTCTFKFGSTDGXXSDELD 577
+G+V + R+ + M L +P D Q CT + S G +D+++
Sbjct: 142 LHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESY-GYTTDDIE 189
>S67368-1|AAB29370.1| 474|Homo sapiens gamma-aminobutyric acid A
receptor beta 2 subunit protein.
Length = 474
Score = 47.6 bits (108), Expect = 5e-05
Identities = 41/169 (24%), Positives = 72/169 (42%), Gaps = 7/169 (4%)
Frame = +2
Query: 92 CAIASAAECENATSLSLMIDSLLATYDRDSPPD---SKIVVNLTLHLRHAN-IRESESTV 259
CA S + N + + +D LL YD PD + V + + + + + E
Sbjct: 23 CA-QSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDIASIDMVSEVNMDY 81
Query: 260 RIQADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTXGDYALRARVSN 439
+ Q W DKRLS+N + +++LW PD LN + ++ R+
Sbjct: 82 TLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIR 141
Query: 440 ---NGSVSWIKRLDISTPISMQLDNWPXDMQTCTFKFGSTDGXXSDELD 577
+G+V + R+ + M L +P D Q CT + S G +D+++
Sbjct: 142 LHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESY-GYTTDDIE 189
>S62907-1|AAB27278.1| 451|Homo sapiens gamma-aminobutyric acidA
receptor alpha 2 subunit protein.
Length = 451
Score = 47.6 bits (108), Expect = 5e-05
Identities = 33/149 (22%), Positives = 64/149 (42%), Gaps = 7/149 (4%)
Frame = +2
Query: 122 NATSLSLMIDSLLATYDRDSPP---DSKIVVNLTLHLRHAN-IRESESTVRIQADLQMNW 289
N T + ++D LL YD P DS V +++ + +++ I + W
Sbjct: 38 NITIFTRILDRLLDGYDNRLRPGLGDSITEVFTNIYVTSFGPVSDTDMEYTIDVFFRQKW 97
Query: 290 IDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTXGDYALR---ARVSNNGSVSWI 460
D+RL + + + ++W PD N + + + R+ ++G++ +
Sbjct: 98 KDERLKFKGPMNILRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRIQDDGTLLYT 157
Query: 461 KRLDISTPISMQLDNWPXDMQTCTFKFGS 547
RL + M L+++P D +C KFGS
Sbjct: 158 MRLTVQAECPMHLEDFPMDAHSCPLKFGS 186
>BC105639-1|AAI05640.1| 474|Homo sapiens GABRB2 protein protein.
Length = 474
Score = 47.6 bits (108), Expect = 5e-05
Identities = 41/169 (24%), Positives = 72/169 (42%), Gaps = 7/169 (4%)
Frame = +2
Query: 92 CAIASAAECENATSLSLMIDSLLATYDRDSPPD---SKIVVNLTLHLRHAN-IRESESTV 259
CA S + N + + +D LL YD PD + V + + + + + E
Sbjct: 23 CA-QSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDIASIDMVSEVNMDY 81
Query: 260 RIQADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTXGDYALRARVSN 439
+ Q W DKRLS+N + +++LW PD LN + ++ R+
Sbjct: 82 TLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIR 141
Query: 440 ---NGSVSWIKRLDISTPISMQLDNWPXDMQTCTFKFGSTDGXXSDELD 577
+G+V + R+ + M L +P D Q CT + S G +D+++
Sbjct: 142 LHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESY-GYTTDDIE 189
>BC099719-1|AAH99719.1| 474|Homo sapiens GABRB2 protein protein.
Length = 474
Score = 47.6 bits (108), Expect = 5e-05
Identities = 41/169 (24%), Positives = 72/169 (42%), Gaps = 7/169 (4%)
Frame = +2
Query: 92 CAIASAAECENATSLSLMIDSLLATYDRDSPPD---SKIVVNLTLHLRHAN-IRESESTV 259
CA S + N + + +D LL YD PD + V + + + + + E
Sbjct: 23 CA-QSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDIASIDMVSEVNMDY 81
Query: 260 RIQADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTXGDYALRARVSN 439
+ Q W DKRLS+N + +++LW PD LN + ++ R+
Sbjct: 82 TLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIR 141
Query: 440 ---NGSVSWIKRLDISTPISMQLDNWPXDMQTCTFKFGSTDGXXSDELD 577
+G+V + R+ + M L +P D Q CT + S G +D+++
Sbjct: 142 LHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESY-GYTTDDIE 189
>BC099705-1|AAH99705.1| 474|Homo sapiens GABRB2 protein protein.
Length = 474
Score = 47.6 bits (108), Expect = 5e-05
Identities = 41/169 (24%), Positives = 72/169 (42%), Gaps = 7/169 (4%)
Frame = +2
Query: 92 CAIASAAECENATSLSLMIDSLLATYDRDSPPD---SKIVVNLTLHLRHAN-IRESESTV 259
CA S + N + + +D LL YD PD + V + + + + + E
Sbjct: 23 CA-QSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDIASIDMVSEVNMDY 81
Query: 260 RIQADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTXGDYALRARVSN 439
+ Q W DKRLS+N + +++LW PD LN + ++ R+
Sbjct: 82 TLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIR 141
Query: 440 ---NGSVSWIKRLDISTPISMQLDNWPXDMQTCTFKFGSTDGXXSDELD 577
+G+V + R+ + M L +P D Q CT + S G +D+++
Sbjct: 142 LHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESY-GYTTDDIE 189
>BC022488-1|AAH22488.1| 367|Homo sapiens GABRA2 protein protein.
Length = 367
Score = 47.6 bits (108), Expect = 5e-05
Identities = 33/149 (22%), Positives = 64/149 (42%), Gaps = 7/149 (4%)
Frame = +2
Query: 122 NATSLSLMIDSLLATYDRDSPP---DSKIVVNLTLHLRHAN-IRESESTVRIQADLQMNW 289
N T + ++D LL YD P DS V +++ + +++ I + W
Sbjct: 38 NITIFTRILDRLLDGYDNRLRPGLGDSITEVFTNIYVTSFGPVSDTDMEYTIDVFFRQKW 97
Query: 290 IDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTXGDYALR---ARVSNNGSVSWI 460
D+RL + + + ++W PD N + + + R+ ++G++ +
Sbjct: 98 KDERLKFKGPMNILRLNNLMASKIWTPDTFFHNGKKSAAHNMTMPNKLLRIQDDGTLLYT 157
Query: 461 KRLDISTPISMQLDNWPXDMQTCTFKFGS 547
RL + M L+++P D +C KFGS
Sbjct: 158 MRLTVQAECPMHLEDFPMDAHSCPLKFGS 186
>AB209295-1|BAD92532.1| 461|Homo sapiens gamma-aminobutyric acid A
receptor, alpha 2 precursor variant protein.
Length = 461
Score = 47.6 bits (108), Expect = 5e-05
Identities = 33/149 (22%), Positives = 64/149 (42%), Gaps = 7/149 (4%)
Frame = +2
Query: 122 NATSLSLMIDSLLATYDRDSPP---DSKIVVNLTLHLRHAN-IRESESTVRIQADLQMNW 289
N T + ++D LL YD P DS V +++ + +++ I + W
Sbjct: 48 NITIFTRILDRLLDGYDNRLRPGLGDSITEVFTNIYVTSFGPVSDTDMEYTIDVFFRQKW 107
Query: 290 IDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTXGDYALR---ARVSNNGSVSWI 460
D+RL + + + ++W PD N + + + R+ ++G++ +
Sbjct: 108 KDERLKFKGPMNILRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRIQDDGTLLYT 167
Query: 461 KRLDISTPISMQLDNWPXDMQTCTFKFGS 547
RL + M L+++P D +C KFGS
Sbjct: 168 MRLTVQAECPMHLEDFPMDAHSCPLKFGS 196
>X14767-1|CAA32875.1| 474|Homo sapiens GABA-A receptor beta 1
subunit protein.
Length = 474
Score = 47.2 bits (107), Expect = 7e-05
Identities = 40/169 (23%), Positives = 71/169 (42%), Gaps = 7/169 (4%)
Frame = +2
Query: 92 CAIASAAECENATSLSLMIDSLLATYDRDSPPD---SKIVVNLTLHLRHAN-IRESESTV 259
C S E N + +D LL YD PD + V + + + + + E
Sbjct: 23 CCAHSTNEPSNMPYVKETVDRLLKGYDIRLRPDFGGPPVDVGMRIDVASIDMVSEVNMDY 82
Query: 260 RIQADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTXGDYALRARVSN 439
+ Q +W DKRLS++ + +++LW PD LN + ++ R+
Sbjct: 83 TLTMYFQQSWKDKRLSYSGIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIR 142
Query: 440 ---NGSVSWIKRLDISTPISMQLDNWPXDMQTCTFKFGSTDGXXSDELD 577
+G+V + R+ + M L +P D Q CT + S G +D+++
Sbjct: 143 LHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESY-GYTTDDIE 190
>BC096083-1|AAH96083.1| 198|Homo sapiens CHRNB4 protein protein.
Length = 198
Score = 47.2 bits (107), Expect = 7e-05
Identities = 30/111 (27%), Positives = 54/111 (48%), Gaps = 8/111 (7%)
Frame = +2
Query: 95 AIASAAECENATSLSLMIDSLL--ATYD---RDSPPDSKIV-VNLTLHLRHA-NIRESES 253
A+ C A + ++D LL Y+ R + S+++ + L L L ++ E E
Sbjct: 14 ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQ 73
Query: 254 TVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATT 403
+ L+ W D RL+WN+ + G + + ++R+W PD+VL N + T
Sbjct: 74 IMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNKSLRT 124
>BC096081-1|AAH96081.1| 198|Homo sapiens CHRNB4 protein protein.
Length = 198
Score = 47.2 bits (107), Expect = 7e-05
Identities = 30/111 (27%), Positives = 54/111 (48%), Gaps = 8/111 (7%)
Frame = +2
Query: 95 AIASAAECENATSLSLMIDSLL--ATYD---RDSPPDSKIV-VNLTLHLRHA-NIRESES 253
A+ C A + ++D LL Y+ R + S+++ + L L L ++ E E
Sbjct: 14 ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQ 73
Query: 254 TVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATT 403
+ L+ W D RL+WN+ + G + + ++R+W PD+VL N + T
Sbjct: 74 IMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNKSLRT 124
>S82769-1|AAB39369.1| 467|Homo sapiens GABAA receptor gamma 3
subunit protein.
Length = 467
Score = 46.8 bits (106), Expect = 1e-04
Identities = 36/147 (24%), Positives = 63/147 (42%), Gaps = 7/147 (4%)
Frame = +2
Query: 128 TSLSLMIDSLLATYDRDSPPDSKI---VVNLTLHLRHAN-IRESESTVRIQADLQMNWID 295
T ++L+++ LL YD+ PD I V+++ +++ + +I W D
Sbjct: 45 TDVTLILNKLLREYDKKLRPDIGIKPTVIDVDIYVNSIGPVSSINMEYQIDIFFAQTWTD 104
Query: 296 KRLSWNAGEWGCSTWLVSSERLWRPDVVLLN---AAATTXGDYALRARVSNNGSVSWIKR 466
RL +N+ + +W PD + N A A R+ N+G + + R
Sbjct: 105 SRLRFNSTMKILTLNSNMVGLIWIPDTIFRNSKTAEAHWITTPNQLLRIWNDGKILYTLR 164
Query: 467 LDISTPISMQLDNWPXDMQTCTFKFGS 547
L I+ +QL N+P D +C F S
Sbjct: 165 LTINAECQLQLHNFPMDEHSCPLIFSS 191
>S82612-1|AAB37533.2| 478|Homo sapiens 5-hydroxytryptamine type 3AS
receptor subunit protein.
Length = 478
Score = 46.8 bits (106), Expect = 1e-04
Identities = 25/106 (23%), Positives = 46/106 (43%), Gaps = 1/106 (0%)
Frame = +2
Query: 233 NIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTXG 409
N+ E + + W D+ L WN ++ T L + ++ +W PD+++
Sbjct: 72 NVDEKNQVLTTYIWYRQYWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINELVDVGKS 131
Query: 410 DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPXDMQTCTFKFGS 547
+ + G V K L + T S+ + N+P D+Q C+ F S
Sbjct: 132 PNIPYVYIRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTS 177
>AF269144-1|AAF99698.1| 467|Homo sapiens GABAA receptor gamma 3
subunit protein.
Length = 467
Score = 46.8 bits (106), Expect = 1e-04
Identities = 36/147 (24%), Positives = 63/147 (42%), Gaps = 7/147 (4%)
Frame = +2
Query: 128 TSLSLMIDSLLATYDRDSPPDSKI---VVNLTLHLRHAN-IRESESTVRIQADLQMNWID 295
T ++L+++ LL YD+ PD I V+++ +++ + +I W D
Sbjct: 45 TDVTLILNKLLREYDKKLRPDIGIKPTVIDVDIYVNSIGPVSSINMEYQIDIFFAQTWTD 104
Query: 296 KRLSWNAGEWGCSTWLVSSERLWRPDVVLLN---AAATTXGDYALRARVSNNGSVSWIKR 466
RL +N+ + +W PD + N A A R+ N+G + + R
Sbjct: 105 SRLRFNSTMKILTLNSNMVGLIWIPDTIFRNSKTAEAHWITTPNQLLRIWNDGKILYTLR 164
Query: 467 LDISTPISMQLDNWPXDMQTCTFKFGS 547
L I+ +QL N+P D +C F S
Sbjct: 165 LTINAECQLQLHNFPMDEHSCPLIFSS 191
>AF228458-1|AAF63215.1| 449|Homo sapiens GABAA receptor gamma 3
subunit protein.
Length = 449
Score = 46.8 bits (106), Expect = 1e-04
Identities = 36/147 (24%), Positives = 63/147 (42%), Gaps = 7/147 (4%)
Frame = +2
Query: 128 TSLSLMIDSLLATYDRDSPPDSKI---VVNLTLHLRHAN-IRESESTVRIQADLQMNWID 295
T ++L+++ LL YD+ PD I V+++ +++ + +I W D
Sbjct: 27 TDVTLILNKLLREYDKKLRPDIGIKPTVIDVDIYVNSIGPVSSINMEYQIDIFFAQTWTD 86
Query: 296 KRLSWNAGEWGCSTWLVSSERLWRPDVVLLN---AAATTXGDYALRARVSNNGSVSWIKR 466
RL +N+ + +W PD + N A A R+ N+G + + R
Sbjct: 87 SRLRFNSTMKILTLNSNMVGLIWIPDTIFRNSKTAEAHWITTPNQLLRIWNDGKILYTLR 146
Query: 467 LDISTPISMQLDNWPXDMQTCTFKFGS 547
L I+ +QL N+P D +C F S
Sbjct: 147 LTINAECQLQLHNFPMDEHSCPLIFSS 173
>U33267-1|AAB37750.1| 497|Homo sapiens glycine receptor beta
subunit protein.
Length = 497
Score = 46.4 bits (105), Expect = 1e-04
Identities = 42/161 (26%), Positives = 69/161 (42%), Gaps = 11/161 (6%)
Frame = +2
Query: 125 ATSLSLMIDSLLATYDRDSPPDSK-----IVVNLTLHLRHANIRESESTVRIQADLQMNW 289
A S S +++ LL +YD P+ K +VVN+ ++ +I+E+ R+ L+ W
Sbjct: 53 ANSTSNILNRLLVSYDPRIRPNFKGIPVDVVVNIFIN-SFGSIQETTMDYRVNIFLRQKW 111
Query: 290 IDKRLSWNAGEWGCSTWLVSSER---LWRPDVVLLNAAATTXGDYA---LRARVSNNGSV 451
D RL + G V LW+PD+ N + D + + +G V
Sbjct: 112 NDPRLKLPSDFRGSDALTVDPTMYKCLWKPDLFFANEKSANFHDVTQENILLFIFRDGDV 171
Query: 452 SWIKRLDISTPISMQLDNWPXDMQTCTFKFGSTDGXXSDEL 574
RL I+ + L +P D Q C + S G +D+L
Sbjct: 172 LVSMRLSITLSCPLDLTLFPMDTQRCKMQLESF-GYTTDDL 211
>S81944-1|AAB36480.1| 453|Homo sapiens gamma-aminobutyric acid type
A receptor alpha 6 subunit protein.
Length = 453
Score = 46.4 bits (105), Expect = 1e-04
Identities = 34/146 (23%), Positives = 61/146 (41%), Gaps = 7/146 (4%)
Frame = +2
Query: 131 SLSLMIDSLLATYDRDSPPD---SKIVVNLTLHLRHAN-IRESESTVRIQADLQMNWIDK 298
++S ++D+LL YD P + V +++ + + E + + W D+
Sbjct: 31 NVSRILDNLLEGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTDE 90
Query: 299 RLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTXGDYALRA---RVSNNGSVSWIKRL 469
RL + S + ++W PD N + + R+ NG++ + RL
Sbjct: 91 RLKFGGPTEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTMRL 150
Query: 470 DISTPISMQLDNWPXDMQTCTFKFGS 547
I+ M+L N+P D C KFGS
Sbjct: 151 TINADCPMRLVNFPMDGHACPLKFGS 176
>D49394-1|BAA08387.1| 478|Homo sapiens serotonin 5-HT3 receptor
protein.
Length = 478
Score = 46.4 bits (105), Expect = 1e-04
Identities = 25/106 (23%), Positives = 46/106 (43%), Gaps = 1/106 (0%)
Frame = +2
Query: 233 NIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTXG 409
N+ E + + W D+ L WN ++ T L + ++ +W PD+++
Sbjct: 72 NVDEKNQVLTTYIWYRQYWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKS 131
Query: 410 DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPXDMQTCTFKFGS 547
+ + G V K L + T S+ + N+P D+Q C+ F S
Sbjct: 132 PNIPYVYIRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTS 177
>BT007204-1|AAP35868.1| 484|Homo sapiens 5-hydroxytryptamine
(serotonin) receptor 3A protein.
Length = 484
Score = 46.4 bits (105), Expect = 1e-04
Identities = 25/106 (23%), Positives = 46/106 (43%), Gaps = 1/106 (0%)
Frame = +2
Query: 233 NIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTXG 409
N+ E + + W D+ L WN ++ T L + ++ +W PD+++
Sbjct: 78 NVDEKNQVLTTYIWYRQYWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKS 137
Query: 410 DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPXDMQTCTFKFGS 547
+ + G V K L + T S+ + N+P D+Q C+ F S
Sbjct: 138 PNIPYVYIRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTS 183
>BC099641-1|AAH99641.1| 453|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 6 protein.
Length = 453
Score = 46.4 bits (105), Expect = 1e-04
Identities = 34/146 (23%), Positives = 61/146 (41%), Gaps = 7/146 (4%)
Frame = +2
Query: 131 SLSLMIDSLLATYDRDSPPD---SKIVVNLTLHLRHAN-IRESESTVRIQADLQMNWIDK 298
++S ++D+LL YD P + V +++ + + E + + W D+
Sbjct: 31 NVSRILDNLLEGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTDE 90
Query: 299 RLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTXGDYALRA---RVSNNGSVSWIKRL 469
RL + S + ++W PD N + + R+ NG++ + RL
Sbjct: 91 RLKFGGPTEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTMRL 150
Query: 470 DISTPISMQLDNWPXDMQTCTFKFGS 547
I+ M+L N+P D C KFGS
Sbjct: 151 TINADCPMRLVNFPMDGHACPLKFGS 176
>BC099640-1|AAH99640.1| 453|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 6 protein.
Length = 453
Score = 46.4 bits (105), Expect = 1e-04
Identities = 34/146 (23%), Positives = 61/146 (41%), Gaps = 7/146 (4%)
Frame = +2
Query: 131 SLSLMIDSLLATYDRDSPPD---SKIVVNLTLHLRHAN-IRESESTVRIQADLQMNWIDK 298
++S ++D+LL YD P + V +++ + + E + + W D+
Sbjct: 31 NVSRILDNLLEGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTDE 90
Query: 299 RLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTXGDYALRA---RVSNNGSVSWIKRL 469
RL + S + ++W PD N + + R+ NG++ + RL
Sbjct: 91 RLKFGGPTEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTMRL 150
Query: 470 DISTPISMQLDNWPXDMQTCTFKFGS 547
I+ M+L N+P D C KFGS
Sbjct: 151 TINADCPMRLVNFPMDGHACPLKFGS 176
>BC096242-1|AAH96242.1| 453|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 6 protein.
Length = 453
Score = 46.4 bits (105), Expect = 1e-04
Identities = 34/146 (23%), Positives = 61/146 (41%), Gaps = 7/146 (4%)
Frame = +2
Query: 131 SLSLMIDSLLATYDRDSPPD---SKIVVNLTLHLRHAN-IRESESTVRIQADLQMNWIDK 298
++S ++D+LL YD P + V +++ + + E + + W D+
Sbjct: 31 NVSRILDNLLEGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTDE 90
Query: 299 RLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTXGDYALRA---RVSNNGSVSWIKRL 469
RL + S + ++W PD N + + R+ NG++ + RL
Sbjct: 91 RLKFGGPTEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTMRL 150
Query: 470 DISTPISMQLDNWPXDMQTCTFKFGS 547
I+ M+L N+P D C KFGS
Sbjct: 151 TINADCPMRLVNFPMDGHACPLKFGS 176
>BC096241-1|AAH96241.1| 453|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 6 protein.
Length = 453
Score = 46.4 bits (105), Expect = 1e-04
Identities = 34/146 (23%), Positives = 61/146 (41%), Gaps = 7/146 (4%)
Frame = +2
Query: 131 SLSLMIDSLLATYDRDSPPD---SKIVVNLTLHLRHAN-IRESESTVRIQADLQMNWIDK 298
++S ++D+LL YD P + V +++ + + E + + W D+
Sbjct: 31 NVSRILDNLLEGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTDE 90
Query: 299 RLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTXGDYALRA---RVSNNGSVSWIKRL 469
RL + S + ++W PD N + + R+ NG++ + RL
Sbjct: 91 RLKFGGPTEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTMRL 150
Query: 470 DISTPISMQLDNWPXDMQTCTFKFGS 547
I+ M+L N+P D C KFGS
Sbjct: 151 TINADCPMRLVNFPMDGHACPLKFGS 176
>BC032635-1|AAH32635.1| 497|Homo sapiens glycine receptor, beta
protein.
Length = 497
Score = 46.4 bits (105), Expect = 1e-04
Identities = 42/161 (26%), Positives = 69/161 (42%), Gaps = 11/161 (6%)
Frame = +2
Query: 125 ATSLSLMIDSLLATYDRDSPPDSK-----IVVNLTLHLRHANIRESESTVRIQADLQMNW 289
A S S +++ LL +YD P+ K +VVN+ ++ +I+E+ R+ L+ W
Sbjct: 53 ANSTSNILNRLLVSYDPRIRPNFKGIPVDVVVNIFIN-SFGSIQETTMDYRVNIFLRQKW 111
Query: 290 IDKRLSWNAGEWGCSTWLVSSER---LWRPDVVLLNAAATTXGDYA---LRARVSNNGSV 451
D RL + G V LW+PD+ N + D + + +G V
Sbjct: 112 NDPRLKLPSDFRGSDALTVDPTMYKCLWKPDLFFANEKSANFHDVTQENILLFIFRDGDV 171
Query: 452 SWIKRLDISTPISMQLDNWPXDMQTCTFKFGSTDGXXSDEL 574
RL I+ + L +P D Q C + S G +D+L
Sbjct: 172 LVSMRLSITLSCPLDLTLFPMDTQRCKMQLESF-GYTTDDL 211
>BC004453-1|AAH04453.2| 478|Homo sapiens 5-hydroxytryptamine
(serotonin) receptor 3A protein.
Length = 478
Score = 46.4 bits (105), Expect = 1e-04
Identities = 25/106 (23%), Positives = 46/106 (43%), Gaps = 1/106 (0%)
Frame = +2
Query: 233 NIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTXG 409
N+ E + + W D+ L WN ++ T L + ++ +W PD+++
Sbjct: 72 NVDEKNQVLTTYIWYRQYWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKS 131
Query: 410 DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPXDMQTCTFKFGS 547
+ + G V K L + T S+ + N+P D+Q C+ F S
Sbjct: 132 PNIPYVYIRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTS 177
>BC002354-1|AAH02354.1| 478|Homo sapiens 5-hydroxytryptamine
(serotonin) receptor 3A protein.
Length = 478
Score = 46.4 bits (105), Expect = 1e-04
Identities = 25/106 (23%), Positives = 46/106 (43%), Gaps = 1/106 (0%)
Frame = +2
Query: 233 NIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTXG 409
N+ E + + W D+ L WN ++ T L + ++ +W PD+++
Sbjct: 72 NVDEKNQVLTTYIWYRQYWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKS 131
Query: 410 DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPXDMQTCTFKFGS 547
+ + G V K L + T S+ + N+P D+Q C+ F S
Sbjct: 132 PNIPYVYIRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTS 177
>AJ005205-1|CAA06442.3| 478|Homo sapiens serotonin 3 receptor
protein.
Length = 478
Score = 46.4 bits (105), Expect = 1e-04
Identities = 25/106 (23%), Positives = 46/106 (43%), Gaps = 1/106 (0%)
Frame = +2
Query: 233 NIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTXG 409
N+ E + + W D+ L WN ++ T L + ++ +W PD+++
Sbjct: 72 NVDEKNQVLTTYIWYRQYWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKS 131
Query: 410 DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPXDMQTCTFKFGS 547
+ + G V K L + T S+ + N+P D+Q C+ F S
Sbjct: 132 PNIPYVYIRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTS 177
>AJ003080-1|CAA05853.1| 238|Homo sapiens serotonin receptor
protein.
Length = 238
Score = 46.4 bits (105), Expect = 1e-04
Identities = 25/106 (23%), Positives = 46/106 (43%), Gaps = 1/106 (0%)
Frame = +2
Query: 233 NIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTXG 409
N+ E + + W D+ L WN ++ T L + ++ +W PD+++
Sbjct: 72 NVDEKNQVLTTYIWYRQYWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKS 131
Query: 410 DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPXDMQTCTFKFGS 547
+ + G V K L + T S+ + N+P D+Q C+ F S
Sbjct: 132 PNIPYVYIRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTS 177
>AJ003079-1|CAA05852.1| 478|Homo sapiens 5-hydroxytryptamine3
receptor protein.
Length = 478
Score = 46.4 bits (105), Expect = 1e-04
Identities = 25/106 (23%), Positives = 46/106 (43%), Gaps = 1/106 (0%)
Frame = +2
Query: 233 NIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTXG 409
N+ E + + W D+ L WN ++ T L + ++ +W PD+++
Sbjct: 72 NVDEKNQVLTTYIWYRQYWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKS 131
Query: 410 DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPXDMQTCTFKFGS 547
+ + G V K L + T S+ + N+P D+Q C+ F S
Sbjct: 132 PNIPYVYIRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTS 177
>AJ003078-1|CAA05851.1| 510|Homo sapiens serotonin receptor
protein.
Length = 510
Score = 46.4 bits (105), Expect = 1e-04
Identities = 25/106 (23%), Positives = 46/106 (43%), Gaps = 1/106 (0%)
Frame = +2
Query: 233 NIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTXG 409
N+ E + + W D+ L WN ++ T L + ++ +W PD+++
Sbjct: 72 NVDEKNQVLTTYIWYRQYWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKS 131
Query: 410 DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPXDMQTCTFKFGS 547
+ + G V K L + T S+ + N+P D+Q C+ F S
Sbjct: 132 PNIPYVYIRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTS 177
>AF498984-1|AAM21131.1| 478|Homo sapiens 5-hydroxytryptamine
receptor 3A protein.
Length = 478
Score = 46.4 bits (105), Expect = 1e-04
Identities = 25/106 (23%), Positives = 46/106 (43%), Gaps = 1/106 (0%)
Frame = +2
Query: 233 NIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTXG 409
N+ E + + W D+ L WN ++ T L + ++ +W PD+++
Sbjct: 72 NVDEKNQVLTTYIWYRQYWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKS 131
Query: 410 DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPXDMQTCTFKFGS 547
+ + G V K L + T S+ + N+P D+Q C+ F S
Sbjct: 132 PNIPYVYIRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTS 177
>AF094755-1|AAC71034.1| 497|Homo sapiens glycine receptor beta
subunit precursor protein.
Length = 497
Score = 46.4 bits (105), Expect = 1e-04
Identities = 42/161 (26%), Positives = 69/161 (42%), Gaps = 11/161 (6%)
Frame = +2
Query: 125 ATSLSLMIDSLLATYDRDSPPDSK-----IVVNLTLHLRHANIRESESTVRIQADLQMNW 289
A S S +++ LL +YD P+ K +VVN+ ++ +I+E+ R+ L+ W
Sbjct: 53 ANSTSNILNRLLVSYDPRIRPNFKGIPVDVVVNIFIN-SFGSIQETTMDYRVNIFLRQKW 111
Query: 290 IDKRLSWNAGEWGCSTWLVSSER---LWRPDVVLLNAAATTXGDYA---LRARVSNNGSV 451
D RL + G V LW+PD+ N + D + + +G V
Sbjct: 112 NDPRLKLPSDFRGSDALTVDPTMYKCLWKPDLFFANEKSANFHDVTQENILLFIFRDGDV 171
Query: 452 SWIKRLDISTPISMQLDNWPXDMQTCTFKFGSTDGXXSDEL 574
RL I+ + L +P D Q C + S G +D+L
Sbjct: 172 LVSMRLSITLSCPLDLTLFPMDTQRCKMQLESF-GYTTDDL 211
>AF094754-1|AAC71033.1| 497|Homo sapiens glycine receptor beta
subunit precursor protein.
Length = 497
Score = 46.4 bits (105), Expect = 1e-04
Identities = 42/161 (26%), Positives = 69/161 (42%), Gaps = 11/161 (6%)
Frame = +2
Query: 125 ATSLSLMIDSLLATYDRDSPPDSK-----IVVNLTLHLRHANIRESESTVRIQADLQMNW 289
A S S +++ LL +YD P+ K +VVN+ ++ +I+E+ R+ L+ W
Sbjct: 53 ANSTSNILNRLLVSYDPRIRPNFKGIPVDVVVNIFIN-SFGSIQETTMDYRVNIFLRQKW 111
Query: 290 IDKRLSWNAGEWGCSTWLVSSER---LWRPDVVLLNAAATTXGDYA---LRARVSNNGSV 451
D RL + G V LW+PD+ N + D + + +G V
Sbjct: 112 NDPRLKLPSDFRGSDALTVDPTMYKCLWKPDLFFANEKSANFHDVTQENILLFIFRDGDV 171
Query: 452 SWIKRLDISTPISMQLDNWPXDMQTCTFKFGSTDGXXSDEL 574
RL I+ + L +P D Q C + S G +D+L
Sbjct: 172 LVSMRLSITLSCPLDLTLFPMDTQRCKMQLESF-GYTTDDL 211
>M82919-1|AAA52511.1| 473|Homo sapiens GABA-alpha receptor beta-3
subunit protein.
Length = 473
Score = 46.0 bits (104), Expect = 2e-04
Identities = 38/169 (22%), Positives = 71/169 (42%), Gaps = 7/169 (4%)
Frame = +2
Query: 92 CAIASAAECENATSLSLMIDSLLATYDRDSPPD---SKIVVNLTLHLRHAN-IRESESTV 259
C S + N + + +D LL YD PD + V + + + + + E
Sbjct: 23 CCAQSVNDPGNMSFVKETVDKLLKGYDIRLRPDFGGPPVCVGMNIDIASIDMVSEVNMDY 82
Query: 260 RIQADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTXGDYALRARVSN 439
+ Q W DKRL+++ + +++LW PD LN + ++ R+
Sbjct: 83 TLTMYFQQYWRDKRLAYSGIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIR 142
Query: 440 ---NGSVSWIKRLDISTPISMQLDNWPXDMQTCTFKFGSTDGXXSDELD 577
+G+V + R+ + M L +P D Q CT + S G +D+++
Sbjct: 143 LHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESY-GYTTDDIE 190
>BC109211-1|AAI09212.1| 632|Homo sapiens gamma-aminobutyric acid
(GABA) receptor, theta protein.
Length = 632
Score = 46.0 bits (104), Expect = 2e-04
Identities = 35/145 (24%), Positives = 60/145 (41%), Gaps = 7/145 (4%)
Frame = +2
Query: 116 CENATSLSLMIDSLLATYDRDSPPD---SKIVVNLTLHLRHAN-IRESESTVRIQADLQM 283
C N + ++D +L+ YD P+ + + V +++++ I E I
Sbjct: 53 CANEAVVQKILDRVLSRYDVRLRPNFGGAPVPVRISIYVTSIEQISEMNMDYTITMFFHQ 112
Query: 284 NWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTXGDYALRARVSN---NGSVS 454
W D RL++ + E+LW PD LN+ D + RV +G+V
Sbjct: 113 TWKDSRLAYYETTLNLTLDYRMHEKLWVPDCYFLNSKDAFVHDVTVENRVFQLHPDGTVR 172
Query: 455 WIKRLDISTPISMQLDNWPXDMQTC 529
+ RL + S+ L +P D Q C
Sbjct: 173 YGIRLTTTAACSLDLHKFPMDKQAC 197
>BC109210-1|AAI09211.1| 632|Homo sapiens gamma-aminobutyric acid
(GABA) receptor, theta protein.
Length = 632
Score = 46.0 bits (104), Expect = 2e-04
Identities = 35/145 (24%), Positives = 60/145 (41%), Gaps = 7/145 (4%)
Frame = +2
Query: 116 CENATSLSLMIDSLLATYDRDSPPD---SKIVVNLTLHLRHAN-IRESESTVRIQADLQM 283
C N + ++D +L+ YD P+ + + V +++++ I E I
Sbjct: 53 CANEAVVQKILDRVLSRYDVRLRPNFGGAPVPVRISIYVTSIEQISEMNMDYTITMFFHQ 112
Query: 284 NWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTXGDYALRARVSN---NGSVS 454
W D RL++ + E+LW PD LN+ D + RV +G+V
Sbjct: 113 TWKDSRLAYYETTLNLTLDYRMHEKLWVPDCYFLNSKDAFVHDVTVENRVFQLHPDGTVR 172
Query: 455 WIKRLDISTPISMQLDNWPXDMQTC 529
+ RL + S+ L +P D Q C
Sbjct: 173 YGIRLTTTAACSLDLHKFPMDKQAC 197
>BC030696-1|AAH30696.1| 456|Homo sapiens GABRA1 protein protein.
Length = 456
Score = 46.0 bits (104), Expect = 2e-04
Identities = 32/150 (21%), Positives = 63/150 (42%), Gaps = 7/150 (4%)
Frame = +2
Query: 119 ENATSLSLMIDSLLATYD-RDSPPDSKIVVNLTLHL---RHANIRESESTVRIQADLQMN 286
+N T + ++D LL YD R P + V + + + + + I + +
Sbjct: 37 DNTTVFTRILDRLLDGYDNRLRPGLGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQS 96
Query: 287 WIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTXGDYALR---ARVSNNGSVSW 457
W D+RL + + + ++W PD N + + + R++ +G++ +
Sbjct: 97 WKDERLKFKGPMTVLRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLY 156
Query: 458 IKRLDISTPISMQLDNWPXDMQTCTFKFGS 547
RL + M L+++P D C KFGS
Sbjct: 157 TMRLTVRAECPMHLEDFPMDAHACPLKFGS 186
>AK223447-1|BAD97167.1| 456|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 1 precursor variant protein.
Length = 456
Score = 46.0 bits (104), Expect = 2e-04
Identities = 32/150 (21%), Positives = 63/150 (42%), Gaps = 7/150 (4%)
Frame = +2
Query: 119 ENATSLSLMIDSLLATYD-RDSPPDSKIVVNLTLHL---RHANIRESESTVRIQADLQMN 286
+N T + ++D LL YD R P + V + + + + + I + +
Sbjct: 37 DNTTVFTRILDRLLDGYDNRLRPGLGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQS 96
Query: 287 WIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTXGDYALR---ARVSNNGSVSW 457
W D+RL + + + ++W PD N + + + R++ +G++ +
Sbjct: 97 WKDERLKFKGPMTVLRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLY 156
Query: 458 IKRLDISTPISMQLDNWPXDMQTCTFKFGS 547
RL + M L+++P D C KFGS
Sbjct: 157 TMRLTVRAECPMHLEDFPMDAHACPLKFGS 186
>AF189259-1|AAF70380.1| 632|Homo sapiens GABA-A receptor theta
subunit protein.
Length = 632
Score = 46.0 bits (104), Expect = 2e-04
Identities = 35/145 (24%), Positives = 60/145 (41%), Gaps = 7/145 (4%)
Frame = +2
Query: 116 CENATSLSLMIDSLLATYDRDSPPD---SKIVVNLTLHLRHAN-IRESESTVRIQADLQM 283
C N + ++D +L+ YD P+ + + V +++++ I E I
Sbjct: 53 CANEAVVQKILDRVLSRYDVRLRPNFGGAPVPVRISIYVTSIEQISEMNMDYTITMFFHQ 112
Query: 284 NWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTXGDYALRARVSN---NGSVS 454
W D RL++ + E+LW PD LN+ D + RV +G+V
Sbjct: 113 TWKDSRLAYYETTLNLTLDYRMHEKLWVPDCYFLNSKDAFVHDVTVENRVFQLHPDGTVR 172
Query: 455 WIKRLDISTPISMQLDNWPXDMQTC 529
+ RL + S+ L +P D Q C
Sbjct: 173 YGIRLTTTAACSLDLHKFPMDKQAC 197
>AF144648-1|AAD51172.1| 627|Homo sapiens GABA-A receptor theta
protein.
Length = 627
Score = 46.0 bits (104), Expect = 2e-04
Identities = 35/145 (24%), Positives = 60/145 (41%), Gaps = 7/145 (4%)
Frame = +2
Query: 116 CENATSLSLMIDSLLATYDRDSPPD---SKIVVNLTLHLRHAN-IRESESTVRIQADLQM 283
C N + ++D +L+ YD P+ + + V +++++ I E I
Sbjct: 48 CANEAVVQKILDRVLSRYDVRLRPNFGGAPVPVRISIYVTSIEQISEMNMDYTITMFFHQ 107
Query: 284 NWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTXGDYALRARVSN---NGSVS 454
W D RL++ + E+LW PD LN+ D + RV +G+V
Sbjct: 108 TWKDSRLAYYETTLNLTLDYRMHEKLWVPDCYFLNSKDAFVHDVTVENRVFQLHPDGTVR 167
Query: 455 WIKRLDISTPISMQLDNWPXDMQTC 529
+ RL + S+ L +P D Q C
Sbjct: 168 YGIRLTTTAACSLDLHKFPMDKQAC 192
>X52009-1|CAA36258.1| 449|Homo sapiens inhibitory glycine receptor
protein.
Length = 449
Score = 45.6 bits (103), Expect = 2e-04
Identities = 29/109 (26%), Positives = 49/109 (44%), Gaps = 4/109 (3%)
Frame = +2
Query: 233 NIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERLWRPDVVLLNAAATTXG 409
+I E+ R+ L+ W D RL++N S + +W+PD+ N
Sbjct: 78 SIAETTMDYRVNIFLRQQWNDPRLAYNEYPDDSLDLDPSMLDSIWKPDLFFANEKGAHFH 137
Query: 410 DYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPXDMQTCTFKFGS 547
+ R+S NG+V + R+ ++ M L N+P D+QTC + S
Sbjct: 138 EITTDNKLLRISRNGNVLYSIRITLTLACPMDLKNFPMDVQTCIMQLES 186
>U30461-1|AAB52519.1| 554|Homo sapiens GABAA receptor subunit
alpha4 protein.
Length = 554
Score = 45.6 bits (103), Expect = 2e-04
Identities = 36/143 (25%), Positives = 62/143 (43%), Gaps = 8/143 (5%)
Frame = +2
Query: 143 MIDSLLATYD-RDSP----PDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLS 307
++DSLL YD R P P +++ ++ + + + E + + WIDKRL
Sbjct: 51 ILDSLLDGYDNRLRPGFGGPVTEVKTDIYV-TSFGPVSDVEMEYTMDVFFRQTWIDKRLK 109
Query: 308 WNAGEWGCSTWLVSSERLWRPDVVLLNAAATTXGDYALRA---RVSNNGSVSWIKRLDIS 478
++ + ++W PD N + + R+ NG++ + RL IS
Sbjct: 110 YDGPIEILRLNNMMVTKVWTPDTFFRNGKKSVSHNMTAPNKLFRIMRNGTILYTMRLTIS 169
Query: 479 TPISMQLDNWPXDMQTCTFKFGS 547
M+L ++P D C KFGS
Sbjct: 170 AECPMRLVDFPMDGHACPLKFGS 192
>BC114947-1|AAI14948.1| 457|Homo sapiens GLRA1 protein protein.
Length = 457
Score = 45.6 bits (103), Expect = 2e-04
Identities = 29/109 (26%), Positives = 49/109 (44%), Gaps = 4/109 (3%)
Frame = +2
Query: 233 NIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERLWRPDVVLLNAAATTXG 409
+I E+ R+ L+ W D RL++N S + +W+PD+ N
Sbjct: 78 SIAETTMDYRVNIFLRQQWNDPRLAYNEYPDDSLDLDPSMLDSIWKPDLFFANEKGAHFH 137
Query: 410 DYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPXDMQTCTFKFGS 547
+ R+S NG+V + R+ ++ M L N+P D+QTC + S
Sbjct: 138 EITTDNKLLRISRNGNVLYSIRITLTLACPMDLKNFPMDVQTCIMQLES 186
>BC074980-1|AAH74980.1| 449|Homo sapiens glycine receptor, alpha 1
(startle disease/hyperekplexia) protein.
Length = 449
Score = 45.6 bits (103), Expect = 2e-04
Identities = 29/109 (26%), Positives = 49/109 (44%), Gaps = 4/109 (3%)
Frame = +2
Query: 233 NIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERLWRPDVVLLNAAATTXG 409
+I E+ R+ L+ W D RL++N S + +W+PD+ N
Sbjct: 78 SIAETTMDYRVNIFLRQQWNDPRLAYNEYPDDSLDLDPSMLDSIWKPDLFFANEKGAHFH 137
Query: 410 DYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPXDMQTCTFKFGS 547
+ R+S NG+V + R+ ++ M L N+P D+QTC + S
Sbjct: 138 EITTDNKLLRISRNGNVLYSIRITLTLACPMDLKNFPMDVQTCIMQLES 186
>BC035055-1|AAH35055.1| 554|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 4 protein.
Length = 554
Score = 45.6 bits (103), Expect = 2e-04
Identities = 36/143 (25%), Positives = 62/143 (43%), Gaps = 8/143 (5%)
Frame = +2
Query: 143 MIDSLLATYD-RDSP----PDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLS 307
++DSLL YD R P P +++ ++ + + + E + + WIDKRL
Sbjct: 51 ILDSLLDGYDNRLRPGFGGPVTEVKTDIYV-TSFGPVSDVEMEYTMDVFFRQTWIDKRLK 109
Query: 308 WNAGEWGCSTWLVSSERLWRPDVVLLNAAATTXGDYALRA---RVSNNGSVSWIKRLDIS 478
++ + ++W PD N + + R+ NG++ + RL IS
Sbjct: 110 YDGPIEILRLNNMMVTKVWTPDTFFRNGKKSVSHNMTAPNKLFRIMRNGTILYTMRLTIS 169
Query: 479 TPISMQLDNWPXDMQTCTFKFGS 547
M+L ++P D C KFGS
Sbjct: 170 AECPMRLVDFPMDGHACPLKFGS 192
>BC033801-1|AAH33801.1| 452|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, delta protein.
Length = 452
Score = 45.6 bits (103), Expect = 2e-04
Identities = 39/150 (26%), Positives = 64/150 (42%), Gaps = 7/150 (4%)
Frame = +2
Query: 146 IDSLLATYDRDSPPD-SKIVVNLTLHLRHANI---RESESTVRIQADLQMNWIDKRLSWN 313
+D L+A Y R+ P VN+ L L A+I E+ + L +W D RLS+N
Sbjct: 44 LDGLIAGYARNFRPGIGGPPVNVALALEVASIDHISEANMEYTMTVFLHQSWRDSRLSYN 103
Query: 314 AGEWGCSTWLVSSERLWRPDVVLLNAAATTXGDYALR---ARVSNNGSVSWIKRLDISTP 484
++LW PD ++NA + D + R+ +G + + R+ +
Sbjct: 104 HTNETLGLDSRFVDKLWLPDTFIVNAKSAWFHDVTVENKLIRLQPDGVILYSIRITSTVA 163
Query: 485 ISMQLDNWPXDMQTCTFKFGSTDGXXSDEL 574
M L +P D Q C S G S+++
Sbjct: 164 CDMDLAKYPMDEQECMLDLESY-GYSSEDI 192
>AL391845-4|CAI15436.1| 452|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, delta protein.
Length = 452
Score = 45.6 bits (103), Expect = 2e-04
Identities = 39/150 (26%), Positives = 64/150 (42%), Gaps = 7/150 (4%)
Frame = +2
Query: 146 IDSLLATYDRDSPPD-SKIVVNLTLHLRHANI---RESESTVRIQADLQMNWIDKRLSWN 313
+D L+A Y R+ P VN+ L L A+I E+ + L +W D RLS+N
Sbjct: 44 LDGLIAGYARNFRPGIGGPPVNVALALEVASIDHISEANMEYTMTVFLHQSWRDSRLSYN 103
Query: 314 AGEWGCSTWLVSSERLWRPDVVLLNAAATTXGDYALR---ARVSNNGSVSWIKRLDISTP 484
++LW PD ++NA + D + R+ +G + + R+ +
Sbjct: 104 HTNETLGLDSRFVDKLWLPDTFIVNAKSAWFHDVTVENKLIRLQPDGVILYSIRITSTVA 163
Query: 485 ISMQLDNWPXDMQTCTFKFGSTDGXXSDEL 574
M L +P D Q C S G S+++
Sbjct: 164 CDMDLAKYPMDEQECMLDLESY-GYSSEDI 192
>AF016917-1|AAB70007.1| 452|Homo sapiens GABA-A receptor delta
subunit protein.
Length = 452
Score = 45.6 bits (103), Expect = 2e-04
Identities = 39/150 (26%), Positives = 64/150 (42%), Gaps = 7/150 (4%)
Frame = +2
Query: 146 IDSLLATYDRDSPPD-SKIVVNLTLHLRHANI---RESESTVRIQADLQMNWIDKRLSWN 313
+D L+A Y R+ P VN+ L L A+I E+ + L +W D RLS+N
Sbjct: 44 LDGLIAGYARNFRPGIGGPPVNVALALEVASIDHISEANMEYTMTVFLHQSWRDSRLSYN 103
Query: 314 AGEWGCSTWLVSSERLWRPDVVLLNAAATTXGDYALR---ARVSNNGSVSWIKRLDISTP 484
++LW PD ++NA + D + R+ +G + + R+ +
Sbjct: 104 HTNETLGLDSRFVDKLWLPDTFIVNAKSAWFHDVTVENKLIRLQPDGVILYSIRITSTVA 163
Query: 485 ISMQLDNWPXDMQTCTFKFGSTDGXXSDEL 574
M L +P D Q C S G S+++
Sbjct: 164 CDMDLAKYPMDEQECMLDLESY-GYSSEDI 192
>Z93848-1|CAI41994.1| 376|Homo sapiens glycine receptor, alpha 4
protein.
Length = 376
Score = 44.4 bits (100), Expect = 5e-04
Identities = 31/125 (24%), Positives = 54/125 (43%), Gaps = 4/125 (3%)
Frame = +2
Query: 185 PDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERL 361
P + N+ ++ ++I ++ R+ L+ W D RLS+ S + +
Sbjct: 28 PPVNVTCNIFIN-SFSSITKTTMDYRVNVFLRQQWNDPRLSYREYPDDSLDLDPSMLDSI 86
Query: 362 WRPDVVLLNAAATTXGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPXDMQTCT 532
W+PD+ N + R+ NG+V + RL + M L N+P D+QTCT
Sbjct: 87 WKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLILSCLMDLKNFPMDIQTCT 146
Query: 533 FKFGS 547
+ S
Sbjct: 147 MQLES 151
>AL049610-1|CAI42158.1| 376|Homo sapiens glycine receptor, alpha 4
protein.
Length = 376
Score = 44.4 bits (100), Expect = 5e-04
Identities = 31/125 (24%), Positives = 54/125 (43%), Gaps = 4/125 (3%)
Frame = +2
Query: 185 PDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERL 361
P + N+ ++ ++I ++ R+ L+ W D RLS+ S + +
Sbjct: 28 PPVNVTCNIFIN-SFSSITKTTMDYRVNVFLRQQWNDPRLSYREYPDDSLDLDPSMLDSI 86
Query: 362 WRPDVVLLNAAATTXGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPXDMQTCT 532
W+PD+ N + R+ NG+V + RL + M L N+P D+QTCT
Sbjct: 87 WKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLILSCLMDLKNFPMDIQTCT 146
Query: 533 FKFGS 547
+ S
Sbjct: 147 MQLES 151
>U93917-1|AAC39917.1| 449|Homo sapiens glycine receptor alpha 3
subunit protein.
Length = 449
Score = 44.0 bits (99), Expect = 7e-04
Identities = 33/144 (22%), Positives = 60/144 (41%), Gaps = 4/144 (2%)
Frame = +2
Query: 185 PDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERL 361
P + N+ ++ +I E+ R+ L+ W D RL+++ S + +
Sbjct: 68 PPVNVTCNIFIN-SFGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPDDSLDLDPSMLDSI 126
Query: 362 WRPDVVLLNAAATTXGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPXDMQTCT 532
W+PD+ N + R+ NG+V + RL ++ M L N+P D+QTC
Sbjct: 127 WKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFPMDVQTCI 186
Query: 533 FKFGSTDGXXSDELDXXIDXXTIQ 604
+ S +D + D +Q
Sbjct: 187 MQLESFGYTMNDLIFEWQDEAPVQ 210
>BC036086-1|AAH36086.1| 464|Homo sapiens glycine receptor, alpha 3
protein.
Length = 464
Score = 44.0 bits (99), Expect = 7e-04
Identities = 33/144 (22%), Positives = 60/144 (41%), Gaps = 4/144 (2%)
Frame = +2
Query: 185 PDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERL 361
P + N+ ++ +I E+ R+ L+ W D RL+++ S + +
Sbjct: 68 PPVNVTCNIFIN-SFGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPDDSLDLDPSMLDSI 126
Query: 362 WRPDVVLLNAAATTXGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPXDMQTCT 532
W+PD+ N + R+ NG+V + RL ++ M L N+P D+QTC
Sbjct: 127 WKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFPMDVQTCI 186
Query: 533 FKFGSTDGXXSDELDXXIDXXTIQ 604
+ S +D + D +Q
Sbjct: 187 MQLESFGYTMNDLIFEWQDEAPVQ 210
>AF017724-1|AAC39919.1| 465|Homo sapiens glycine receptor alpha 3
subunit protein.
Length = 465
Score = 44.0 bits (99), Expect = 7e-04
Identities = 33/144 (22%), Positives = 60/144 (41%), Gaps = 4/144 (2%)
Frame = +2
Query: 185 PDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERL 361
P + N+ ++ +I E+ R+ L+ W D RL+++ S + +
Sbjct: 68 PPVNVTCNIFIN-SFGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPDDSLDLDPSMLDSI 126
Query: 362 WRPDVVLLNAAATTXGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPXDMQTCT 532
W+PD+ N + R+ NG+V + RL ++ M L N+P D+QTC
Sbjct: 127 WKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFPMDVQTCI 186
Query: 533 FKFGSTDGXXSDELDXXIDXXTIQ 604
+ S +D + D +Q
Sbjct: 187 MQLESFGYTMNDLIFEWQDEAPVQ 210
>U95367-1|AAC51357.1| 440|Homo sapiens GABA-A receptor pi subunit
protein.
Length = 440
Score = 43.6 bits (98), Expect = 9e-04
Identities = 39/154 (25%), Positives = 71/154 (46%), Gaps = 9/154 (5%)
Frame = +2
Query: 113 ECENATSLSLM-IDSLLATYDRDSPPD---SKIVVNLTLHLRH-ANIRESESTVRIQADL 277
E + LSL ++L A Y++ P+ + + LTL + ++I ES L
Sbjct: 29 EVGRSDKLSLPGFENLTAGYNKFLRPNFGGEPVQIALTLDIASISSISESNMDYTATIYL 88
Query: 278 QMNWIDKRLSWNAGE-WGCSTWLVSSERLWRPDVVLLNAAATTXGDYALR---ARVSNNG 445
+ W+D+RL + + + LV E LW PD ++ + + + + R+ +NG
Sbjct: 89 RQRWMDQRLVFEGNKSFTLDARLV--EFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNG 146
Query: 446 SVSWIKRLDISTPISMQLDNWPXDMQTCTFKFGS 547
+V + R+ + +M L +P D QTC + S
Sbjct: 147 TVLYALRITTTVACNMDLSKYPMDTQTCKLQLES 180
>BC109106-1|AAI09107.1| 440|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, pi protein.
Length = 440
Score = 43.6 bits (98), Expect = 9e-04
Identities = 39/154 (25%), Positives = 71/154 (46%), Gaps = 9/154 (5%)
Frame = +2
Query: 113 ECENATSLSLM-IDSLLATYDRDSPPD---SKIVVNLTLHLRH-ANIRESESTVRIQADL 277
E + LSL ++L A Y++ P+ + + LTL + ++I ES L
Sbjct: 29 EVGRSDKLSLPGFENLTAGYNKFLRPNFGGEPVQIALTLDIASISSISESNMDYTATIYL 88
Query: 278 QMNWIDKRLSWNAGE-WGCSTWLVSSERLWRPDVVLLNAAATTXGDYALR---ARVSNNG 445
+ W+D+RL + + + LV E LW PD ++ + + + + R+ +NG
Sbjct: 89 RQRWMDQRLVFEGNKSFTLDARLV--EFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNG 146
Query: 446 SVSWIKRLDISTPISMQLDNWPXDMQTCTFKFGS 547
+V + R+ + +M L +P D QTC + S
Sbjct: 147 TVLYALRITTTVACNMDLSKYPMDTQTCKLQLES 180
>BC109105-1|AAI09106.1| 440|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, pi protein.
Length = 440
Score = 43.6 bits (98), Expect = 9e-04
Identities = 39/154 (25%), Positives = 71/154 (46%), Gaps = 9/154 (5%)
Frame = +2
Query: 113 ECENATSLSLM-IDSLLATYDRDSPPD---SKIVVNLTLHLRH-ANIRESESTVRIQADL 277
E + LSL ++L A Y++ P+ + + LTL + ++I ES L
Sbjct: 29 EVGRSDKLSLPGFENLTAGYNKFLRPNFGGEPVQIALTLDIASISSISESNMDYTATIYL 88
Query: 278 QMNWIDKRLSWNAGE-WGCSTWLVSSERLWRPDVVLLNAAATTXGDYALR---ARVSNNG 445
+ W+D+RL + + + LV E LW PD ++ + + + + R+ +NG
Sbjct: 89 RQRWMDQRLVFEGNKSFTLDARLV--EFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNG 146
Query: 446 SVSWIKRLDISTPISMQLDNWPXDMQTCTFKFGS 547
+V + R+ + +M L +P D QTC + S
Sbjct: 147 TVLYALRITTTVACNMDLSKYPMDTQTCKLQLES 180
>BC074865-1|AAH74865.1| 440|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, pi protein.
Length = 440
Score = 43.6 bits (98), Expect = 9e-04
Identities = 39/154 (25%), Positives = 71/154 (46%), Gaps = 9/154 (5%)
Frame = +2
Query: 113 ECENATSLSLM-IDSLLATYDRDSPPD---SKIVVNLTLHLRH-ANIRESESTVRIQADL 277
E + LSL ++L A Y++ P+ + + LTL + ++I ES L
Sbjct: 29 EVGRSDKLSLPGFENLTAGYNKFLRPNFGGEPVQIALTLDIASISSISESNMDYTATIYL 88
Query: 278 QMNWIDKRLSWNAGE-WGCSTWLVSSERLWRPDVVLLNAAATTXGDYALR---ARVSNNG 445
+ W+D+RL + + + LV E LW PD ++ + + + + R+ +NG
Sbjct: 89 RQRWMDQRLVFEGNKSFTLDARLV--EFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNG 146
Query: 446 SVSWIKRLDISTPISMQLDNWPXDMQTCTFKFGS 547
+V + R+ + +M L +P D QTC + S
Sbjct: 147 TVLYALRITTTVACNMDLSKYPMDTQTCKLQLES 180
>BC074810-1|AAH74810.1| 440|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, pi protein.
Length = 440
Score = 43.6 bits (98), Expect = 9e-04
Identities = 39/154 (25%), Positives = 71/154 (46%), Gaps = 9/154 (5%)
Frame = +2
Query: 113 ECENATSLSLM-IDSLLATYDRDSPPD---SKIVVNLTLHLRH-ANIRESESTVRIQADL 277
E + LSL ++L A Y++ P+ + + LTL + ++I ES L
Sbjct: 29 EVGRSDKLSLPGFENLTAGYNKFLRPNFGGEPVQIALTLDIASISSISESNMDYTATIYL 88
Query: 278 QMNWIDKRLSWNAGE-WGCSTWLVSSERLWRPDVVLLNAAATTXGDYALR---ARVSNNG 445
+ W+D+RL + + + LV E LW PD ++ + + + + R+ +NG
Sbjct: 89 RQRWMDQRLVFEGNKSFTLDARLV--EFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNG 146
Query: 446 SVSWIKRLDISTPISMQLDNWPXDMQTCTFKFGS 547
+V + R+ + +M L +P D QTC + S
Sbjct: 147 TVLYALRITTTVACNMDLSKYPMDTQTCKLQLES 180
>AF009702-1|AAC24194.1| 440|Homo sapiens GABA-A receptor pi subunit
protein.
Length = 440
Score = 43.6 bits (98), Expect = 9e-04
Identities = 39/154 (25%), Positives = 71/154 (46%), Gaps = 9/154 (5%)
Frame = +2
Query: 113 ECENATSLSLM-IDSLLATYDRDSPPD---SKIVVNLTLHLRH-ANIRESESTVRIQADL 277
E + LSL ++L A Y++ P+ + + LTL + ++I ES L
Sbjct: 29 EVGRSDKLSLPGFENLTAGYNKFLRPNFGGEPVQIALTLDIASISSISESNMDYTATIYL 88
Query: 278 QMNWIDKRLSWNAGE-WGCSTWLVSSERLWRPDVVLLNAAATTXGDYALR---ARVSNNG 445
+ W+D+RL + + + LV E LW PD ++ + + + + R+ +NG
Sbjct: 89 RQRWMDQRLVFEGNKSFTLDARLV--EFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNG 146
Query: 446 SVSWIKRLDISTPISMQLDNWPXDMQTCTFKFGS 547
+V + R+ + +M L +P D QTC + S
Sbjct: 147 TVLYALRITTTVACNMDLSKYPMDTQTCKLQLES 180
>BC114967-1|AAI14968.1| 366|Homo sapiens GLRA1 protein protein.
Length = 366
Score = 43.2 bits (97), Expect = 0.001
Identities = 27/100 (27%), Positives = 45/100 (45%), Gaps = 4/100 (4%)
Frame = +2
Query: 260 RIQADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERLWRPDVVLLNAAATTXGDYALR---A 427
R+ L+ W D RL++N S + +W+PD+ N +
Sbjct: 4 RVNIFLRQQWNDPRLAYNEYPDDSLDLDPSMLDSIWKPDLFFANEKGAHFHEITTDNKLL 63
Query: 428 RVSNNGSVSWIKRLDISTPISMQLDNWPXDMQTCTFKFGS 547
R+S NG+V + R+ ++ M L N+P D+QTC + S
Sbjct: 64 RISRNGNVLYSIRITLTLACPMDLKNFPMDVQTCIMQLES 103
>BC010641-1|AAH10641.1| 473|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, beta 3 protein.
Length = 473
Score = 43.2 bits (97), Expect = 0.001
Identities = 37/169 (21%), Positives = 70/169 (41%), Gaps = 7/169 (4%)
Frame = +2
Query: 92 CAIASAAECENATSLSLMIDSLLATYDRDSPPD---SKIVVNLTLHLRHAN-IRESESTV 259
C S + N + + +D LL YD PD + V + + + + + E
Sbjct: 23 CCAQSVNDPGNMSFVKETVDKLLKGYDIRLRPDFGGPPVCVGMNIDIASIDMVSEVNMDY 82
Query: 260 RIQADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTXGDYALRARVSN 439
+ Q W DKRL+++ + +++LW PD LN + ++ R+
Sbjct: 83 TLTMYFQQYWRDKRLAYSGIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIR 142
Query: 440 ---NGSVSWIKRLDISTPISMQLDNWPXDMQTCTFKFGSTDGXXSDELD 577
+G+V + R+ + M L +P D CT + S G +D+++
Sbjct: 143 LHPDGTVLYGLRITTTAACMMDLRRYPLDELNCTLEIESY-GYTTDDIE 190
>BC022449-1|AAH22449.1| 474|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, beta 1 protein.
Length = 474
Score = 42.7 bits (96), Expect = 0.002
Identities = 39/169 (23%), Positives = 71/169 (42%), Gaps = 7/169 (4%)
Frame = +2
Query: 92 CAIASAAECENATSLSLMIDSLLATYDRDSPPD---SKIVVNLTLHLRHAN-IRESESTV 259
C S E N + + +D LL YD PD + V + + + + + E
Sbjct: 23 CCAHSTNEPSNMSYVKETVDRLLKGYDIRLRPDFGGPPVDVGMRIDVASIDMVSEVNMDY 82
Query: 260 RIQADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTXGDYALRARVSN 439
+ Q +W DKRLS++ + +++L PD LN + ++ R+
Sbjct: 83 TLTMYFQQSWKDKRLSYSGIPLNLTLDNRVADQLCVPDTYFLNDKKSFVHGVTVKNRMIR 142
Query: 440 ---NGSVSWIKRLDISTPISMQLDNWPXDMQTCTFKFGSTDGXXSDELD 577
+G+V + R+ + M L +P D Q CT + S G +D+++
Sbjct: 143 LHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESY-GYTTDDIE 190
>AC093745-1|AAY40994.1| 222|Homo sapiens unknown protein.
Length = 222
Score = 42.7 bits (96), Expect = 0.002
Identities = 22/107 (20%), Positives = 47/107 (43%), Gaps = 3/107 (2%)
Frame = +2
Query: 236 IRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTXGDY 415
+ +++ I + W D+RL + + + ++W PD N + +
Sbjct: 17 VSDTDMEYTIDVFFRQKWKDERLKFKGPMNILRLNNLMASKIWTPDTFFHNGKKSVAHNM 76
Query: 416 ALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPXDMQTCTFKFGS 547
+ R+ ++G++ + RL + M L+++P D +C KFGS
Sbjct: 77 TMPNKLLRIQDDGTLLYTMRLTVQAECPMHLEDFPMDAHSCPLKFGS 123
>X13584-1|CAA31925.1| 354|Homo sapiens protein ( Human mRNA for
gamma-aminobutyric-acid receptor alpha-subunit (GABA-A
receptor alpha-subunit). ).
Length = 354
Score = 41.9 bits (94), Expect = 0.003
Identities = 32/147 (21%), Positives = 61/147 (41%), Gaps = 4/147 (2%)
Frame = +2
Query: 119 ENATSLSLMIDSLLATYD-RDSPPDSKIVVNLTLHL---RHANIRESESTVRIQADLQMN 286
+N T + ++D LL YD R P + V + + + + + I + +
Sbjct: 37 DNTTVFTRILDRLLDGYDNRLRPGLGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQS 96
Query: 287 WIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTXGDYALRARVSNNGSVSWIKR 466
W D+RL + + + ++W PD + N R++ +G++ + R
Sbjct: 97 WKDERLKFKGPMTVLRLNNLMASKIWTPDTFMPNKLL----------RITEDGTLLYTMR 146
Query: 467 LDISTPISMQLDNWPXDMQTCTFKFGS 547
L + M L+++P D C KFGS
Sbjct: 147 LTVRAECPMHLEDFPMDAHACPLKFGS 173
>BC074795-1|AAH74795.1| 467|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, gamma 2 protein.
Length = 467
Score = 41.9 bits (94), Expect = 0.003
Identities = 34/145 (23%), Positives = 61/145 (42%), Gaps = 7/145 (4%)
Frame = +2
Query: 134 LSLMIDSLLATYDRDSPPDSKIVVNLTLHLRHANIRESESTVRIQADLQM----NWIDKR 301
+++++++LL YD PD + L + N + + ++ + + W D+R
Sbjct: 66 VTVILNNLLEGYDNKLRPDIGVKPTLIHTDMYVNSIGPVNAINMEYTIDIFFAQTWYDRR 125
Query: 302 LSWNAGEWGCSTWLVSSERLWRPDVVLLN---AAATTXGDYALRARVSNNGSVSWIKRLD 472
L +N+ ++W PD N A A R+ N+G V + RL
Sbjct: 126 LKFNSTIKVLRLNSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYTLRLT 185
Query: 473 ISTPISMQLDNWPXDMQTCTFKFGS 547
I +QL N+P D +C +F S
Sbjct: 186 IDAECQLQLHNFPMDEHSCPLEFSS 210
>BC069348-1|AAH69348.1| 467|Homo sapiens gamma-aminobutyric acid A
receptor, gamma 2, isoform 2 precursor protein.
Length = 467
Score = 41.9 bits (94), Expect = 0.003
Identities = 34/145 (23%), Positives = 61/145 (42%), Gaps = 7/145 (4%)
Frame = +2
Query: 134 LSLMIDSLLATYDRDSPPDSKIVVNLTLHLRHANIRESESTVRIQADLQM----NWIDKR 301
+++++++LL YD PD + L + N + + ++ + + W D+R
Sbjct: 66 VTVILNNLLEGYDNKLRPDIGVKPTLIHTDMYVNSIGPVNAINMEYTIDIFFAQTWYDRR 125
Query: 302 LSWNAGEWGCSTWLVSSERLWRPDVVLLN---AAATTXGDYALRARVSNNGSVSWIKRLD 472
L +N+ ++W PD N A A R+ N+G V + RL
Sbjct: 126 LKFNSTIKVLRLNSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYTLRLT 185
Query: 473 ISTPISMQLDNWPXDMQTCTFKFGS 547
I +QL N+P D +C +F S
Sbjct: 186 IDAECQLQLHNFPMDEHSCPLEFSS 210
>BC059389-1|AAH59389.1| 475|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, gamma 2 protein.
Length = 475
Score = 41.9 bits (94), Expect = 0.003
Identities = 34/145 (23%), Positives = 61/145 (42%), Gaps = 7/145 (4%)
Frame = +2
Query: 134 LSLMIDSLLATYDRDSPPDSKIVVNLTLHLRHANIRESESTVRIQADLQM----NWIDKR 301
+++++++LL YD PD + L + N + + ++ + + W D+R
Sbjct: 66 VTVILNNLLEGYDNKLRPDIGVKPTLIHTDMYVNSIGPVNAINMEYTIDIFFAQTWYDRR 125
Query: 302 LSWNAGEWGCSTWLVSSERLWRPDVVLLN---AAATTXGDYALRARVSNNGSVSWIKRLD 472
L +N+ ++W PD N A A R+ N+G V + RL
Sbjct: 126 LKFNSTIKVLRLNSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYTLRLT 185
Query: 473 ISTPISMQLDNWPXDMQTCTFKFGS 547
I +QL N+P D +C +F S
Sbjct: 186 IDAECQLQLHNFPMDEHSCPLEFSS 210
>AF165124-1|AAD50273.1| 467|Homo sapiens gamma-aminobutyric acid A
receptor gamma 2 protein.
Length = 467
Score = 41.9 bits (94), Expect = 0.003
Identities = 34/145 (23%), Positives = 61/145 (42%), Gaps = 7/145 (4%)
Frame = +2
Query: 134 LSLMIDSLLATYDRDSPPDSKIVVNLTLHLRHANIRESESTVRIQADLQM----NWIDKR 301
+++++++LL YD PD + L + N + + ++ + + W D+R
Sbjct: 66 VTVILNNLLEGYDNKLRPDIGVKPTLIHTDMYVNSIGPVNAINMEYTIDIFFAQTWYDRR 125
Query: 302 LSWNAGEWGCSTWLVSSERLWRPDVVLLN---AAATTXGDYALRARVSNNGSVSWIKRLD 472
L +N+ ++W PD N A A R+ N+G V + RL
Sbjct: 126 LKFNSTIKVLRLNSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYTLRLT 185
Query: 473 ISTPISMQLDNWPXDMQTCTFKFGS 547
I +QL N+P D +C +F S
Sbjct: 186 IDAECQLQLHNFPMDEHSCPLEFSS 210
>X15376-1|CAA33437.1| 467|Homo sapiens GABA-A receptor gamma 2
subunit protein.
Length = 467
Score = 40.7 bits (91), Expect = 0.006
Identities = 34/145 (23%), Positives = 61/145 (42%), Gaps = 7/145 (4%)
Frame = +2
Query: 134 LSLMIDSLLATYDRDSPPDSKIVVNLTLHLRHANIRESESTVRIQADLQM----NWIDKR 301
+++++++LL YD PD + L + N + + ++ + + W D+R
Sbjct: 66 VTVILNNLLEGYDNKLRPDIGVKPTLIHTDMYVNSIGPVNAINMEYTIDIFFAQMWYDRR 125
Query: 302 LSWNAGEWGCSTWLVSSERLWRPDVVLLN---AAATTXGDYALRARVSNNGSVSWIKRLD 472
L +N+ ++W PD N A A R+ N+G V + RL
Sbjct: 126 LKFNSTIKVLRLNSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYSLRLT 185
Query: 473 ISTPISMQLDNWPXDMQTCTFKFGS 547
I +QL N+P D +C +F S
Sbjct: 186 IDAECQLQLHNFPMDEHSCPLEFSS 210
>X14766-1|CAA32874.1| 456|Homo sapiens GABA-A receptor alpha 1
subunit protein.
Length = 456
Score = 40.3 bits (90), Expect = 0.008
Identities = 31/150 (20%), Positives = 62/150 (41%), Gaps = 7/150 (4%)
Frame = +2
Query: 119 ENATSLSLMIDSLLATYD-RDSPPDSKIVVNLTLHL---RHANIRESESTVRIQADLQMN 286
+N T + ++D LL YD R P + V + + + + + I + +
Sbjct: 37 DNTTVFTRILDRLLDGYDNRLRPGLGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQS 96
Query: 287 WIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTXGDYALR---ARVSNNGSVSW 457
W D+RL + + + ++ PD N + + + R++ +G++ +
Sbjct: 97 WKDERLKFKGPMTVLRLNNLMASKIRTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLY 156
Query: 458 IKRLDISTPISMQLDNWPXDMQTCTFKFGS 547
RL + M L+++P D C KFGS
Sbjct: 157 TMRLTVRAECPMHLEDFPMDAHACPLKFGS 186
>BC031087-1|AAH31087.1| 465|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, gamma 1 protein.
Length = 465
Score = 40.3 bits (90), Expect = 0.008
Identities = 35/155 (22%), Positives = 64/155 (41%), Gaps = 7/155 (4%)
Frame = +2
Query: 134 LSLMIDSLLATYDRDSPPDSKI---VVNLTLHLRHAN-IRESESTVRIQADLQMNWIDKR 301
++ +++SLL YD PD + V+ +++ + I W D R
Sbjct: 64 ITQILNSLLQGYDNKLRPDIGVRPTVIETDVYVNSIGPVDPINMEYTIDIIFAQTWFDSR 123
Query: 302 LSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTXGDYALR---ARVSNNGSVSWIKRLD 472
L +N+ ++W PD N+ + R+ N+G V + RL
Sbjct: 124 LKFNSTMKVLMLNSNMVGKIWIPDTFFRNSRKSDAHWITTPNRLLRIWNDGRVLYTLRLT 183
Query: 473 ISTPISMQLDNWPXDMQTCTFKFGSTDGXXSDELD 577
I+ +QL N+P D +C +F S+ G +E++
Sbjct: 184 INAECYLQLHNFPMDEHSCPLEF-SSYGYPKNEIE 217
>M86868-1|AAA52510.1| 465|Homo sapiens gamma-amino butyric acid
protein.
Length = 465
Score = 37.9 bits (84), Expect = 0.044
Identities = 27/111 (24%), Positives = 55/111 (49%), Gaps = 6/111 (5%)
Frame = +2
Query: 233 NIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTW---LVSSERLWRPDVVLLNAAATT 403
+I E + + L+ W D+RL++++ T+ LV +++W PDV +++ +
Sbjct: 90 SISEVDMDFTMTLYLRHYWKDERLAFSSASNKSMTFDGRLV--KKIWVPDVFFVHSKRSF 147
Query: 404 XGDYA---LRARVSNNGSVSWIKRLDISTPISMQLDNWPXDMQTCTFKFGS 547
D + RV +G V + R+ ++ +M ++P D QTC+ + S
Sbjct: 148 THDTTTDNIMLRVFPDGHVLYSMRITVTAMCNMDFSHFPLDSQTCSLELES 198
>BC130354-1|AAI30355.1| 465|Homo sapiens gamma-aminobutyric acid
(GABA) receptor, rho 2 protein.
Length = 465
Score = 37.9 bits (84), Expect = 0.044
Identities = 27/111 (24%), Positives = 55/111 (49%), Gaps = 6/111 (5%)
Frame = +2
Query: 233 NIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTW---LVSSERLWRPDVVLLNAAATT 403
+I E + + L+ W D+RL++++ T+ LV +++W PDV +++ +
Sbjct: 90 SISEVDMDFTMTLYLRHYWKDERLAFSSASNKSMTFDGRLV--KKIWVPDVFFVHSKRSF 147
Query: 404 XGDYA---LRARVSNNGSVSWIKRLDISTPISMQLDNWPXDMQTCTFKFGS 547
D + RV +G V + R+ ++ +M ++P D QTC+ + S
Sbjct: 148 THDTTTDNIMLRVFPDGHVLYSMRITVTAMCNMDFSHFPLDSQTCSLELES 198
>BC130352-1|AAI30353.1| 465|Homo sapiens gamma-aminobutyric acid
(GABA) receptor, rho 2 protein.
Length = 465
Score = 37.9 bits (84), Expect = 0.044
Identities = 27/111 (24%), Positives = 55/111 (49%), Gaps = 6/111 (5%)
Frame = +2
Query: 233 NIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTW---LVSSERLWRPDVVLLNAAATT 403
+I E + + L+ W D+RL++++ T+ LV +++W PDV +++ +
Sbjct: 90 SISEVDMDFTMTLYLRHYWKDERLAFSSASNKSMTFDGRLV--KKIWVPDVFFVHSKRSF 147
Query: 404 XGDYA---LRARVSNNGSVSWIKRLDISTPISMQLDNWPXDMQTCTFKFGS 547
D + RV +G V + R+ ++ +M ++P D QTC+ + S
Sbjct: 148 THDTTTDNIMLRVFPDGHVLYSMRITVTAMCNMDFSHFPLDSQTCSLELES 198
>AL121833-2|CAC07339.1| 465|Homo sapiens gamma-aminobutyric acid
(GABA) receptor, rho 2 protein.
Length = 465
Score = 37.9 bits (84), Expect = 0.044
Identities = 27/111 (24%), Positives = 55/111 (49%), Gaps = 6/111 (5%)
Frame = +2
Query: 233 NIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTW---LVSSERLWRPDVVLLNAAATT 403
+I E + + L+ W D+RL++++ T+ LV +++W PDV +++ +
Sbjct: 90 SISEVDMDFTMTLYLRHYWKDERLAFSSASNKSMTFDGRLV--KKIWVPDVFFVHSKRSF 147
Query: 404 XGDYA---LRARVSNNGSVSWIKRLDISTPISMQLDNWPXDMQTCTFKFGS 547
D + RV +G V + R+ ++ +M ++P D QTC+ + S
Sbjct: 148 THDTTTDNIMLRVFPDGHVLYSMRITVTAMCNMDFSHFPLDSQTCSLELES 198
>AM293589-1|CAL25321.1| 430|Homo sapiens 5-hydroxytryptamine
receptor 3 subunit B protein.
Length = 430
Score = 36.3 bits (80), Expect = 0.13
Identities = 19/88 (21%), Positives = 41/88 (46%), Gaps = 1/88 (1%)
Frame = +2
Query: 287 WIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTXGDYALRARVSNNGSVSWIK 463
W D+ LSWN+ + + + +W PD+++ V+++G++ K
Sbjct: 77 WNDEFLSWNSSMFDEIREISLPLSAIWAPDIIINEFVDIERSPDLPYVYVNSSGTIENYK 136
Query: 464 RLDISTPISMQLDNWPXDMQTCTFKFGS 547
+ + + S++ +P D+Q C+ F S
Sbjct: 137 PIQVVSACSLETYAFPFDVQNCSLTFKS 164
>AF169255-1|AAF03691.1| 441|Homo sapiens 5-hydroxytryptamine 3
receptor B subunit protein.
Length = 441
Score = 35.1 bits (77), Expect = 0.31
Identities = 19/88 (21%), Positives = 41/88 (46%), Gaps = 1/88 (1%)
Frame = +2
Query: 287 WIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTXGDYALRARVSNNGSVSWIK 463
W D+ LSWN+ + + + +W PD+++ V+++G++ K
Sbjct: 88 WNDEFLSWNSSMFDEIREISLPLSAIWAPDIIINEFVDIERYPDLPYVYVNSSGTIENYK 147
Query: 464 RLDISTPISMQLDNWPXDMQTCTFKFGS 547
+ + + S++ +P D+Q C+ F S
Sbjct: 148 PIQVVSACSLETYAFPFDVQNCSLTFKS 175
>AF080582-1|AAD12242.1| 441|Homo sapiens 5-hydroxytryptamine 3
receptor B subunit precursor protein.
Length = 441
Score = 35.1 bits (77), Expect = 0.31
Identities = 19/88 (21%), Positives = 41/88 (46%), Gaps = 1/88 (1%)
Frame = +2
Query: 287 WIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTXGDYALRARVSNNGSVSWIK 463
W D+ LSWN+ + + + +W PD+++ V+++G++ K
Sbjct: 88 WNDEFLSWNSSMFDEIREISLPLSAIWAPDIIINEFVDIERYPDLPYVYVNSSGTIENYK 147
Query: 464 RLDISTPISMQLDNWPXDMQTCTFKFGS 547
+ + + S++ +P D+Q C+ F S
Sbjct: 148 PIQVVSACSLETYAFPFDVQNCSLTFKS 175
>M62400-1|AAA52509.1| 473|Homo sapiens gamma-aminobutyric acid
receptor type A rho-1 subunit protein.
Length = 473
Score = 34.7 bits (76), Expect = 0.41
Identities = 27/111 (24%), Positives = 53/111 (47%), Gaps = 6/111 (5%)
Frame = +2
Query: 233 NIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTW---LVSSERLWRPDVVLLNAAATT 403
+I E + + L+ W D+RLS+ + T+ LV +++W PD+ +++ +
Sbjct: 104 SISEVDMDFTMTLYLRHYWKDERLSFPSTNNLSMTFDGRLV--KKIWVPDMFFVHSKRSF 161
Query: 404 XGDYA---LRARVSNNGSVSWIKRLDISTPISMQLDNWPXDMQTCTFKFGS 547
D + RV +G V + R+ ++ +M +P D QTC+ + S
Sbjct: 162 IHDTTTDNVMLRVQPDGKVLYSLRVTVTAMCNMDFSRFPLDTQTCSLEIES 212
>BC130344-1|AAI30345.1| 474|Homo sapiens gamma-aminobutyric acid
(GABA) receptor, rho 1 protein.
Length = 474
Score = 34.7 bits (76), Expect = 0.41
Identities = 27/111 (24%), Positives = 53/111 (47%), Gaps = 6/111 (5%)
Frame = +2
Query: 233 NIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTW---LVSSERLWRPDVVLLNAAATT 403
+I E + + L+ W D+RLS+ + T+ LV +++W PD+ +++ +
Sbjct: 105 SISEVDMDFTMTLYLRHYWKDERLSFPSTNNLSMTFDGRLV--KKIWVPDMFFVHSKRSF 162
Query: 404 XGDYA---LRARVSNNGSVSWIKRLDISTPISMQLDNWPXDMQTCTFKFGS 547
D + RV +G V + R+ ++ +M +P D QTC+ + S
Sbjct: 163 IHDTTTDNVMLRVQPDGKVLYSLRVTVTAMCNMDFSRFPLDTQTCSLEIES 213
>AL353659-1|CAC36328.2| 473|Homo sapiens gamma-aminobutyric acid
(GABA) receptor, rho 1 protein.
Length = 473
Score = 34.7 bits (76), Expect = 0.41
Identities = 27/111 (24%), Positives = 53/111 (47%), Gaps = 6/111 (5%)
Frame = +2
Query: 233 NIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTW---LVSSERLWRPDVVLLNAAATT 403
+I E + + L+ W D+RLS+ + T+ LV +++W PD+ +++ +
Sbjct: 104 SISEVDMDFTMTLYLRHYWKDERLSFPSTNNLSMTFDGRLV--KKIWVPDMFFVHSKRSF 161
Query: 404 XGDYA---LRARVSNNGSVSWIKRLDISTPISMQLDNWPXDMQTCTFKFGS 547
D + RV +G V + R+ ++ +M +P D QTC+ + S
Sbjct: 162 IHDTTTDNVMLRVQPDGKVLYSLRVTVTAMCNMDFSRFPLDTQTCSLEIES 212
>AL353135-3|CAI16246.1| 473|Homo sapiens gamma-aminobutyric acid
(GABA) receptor, rho 1 protein.
Length = 473
Score = 34.7 bits (76), Expect = 0.41
Identities = 27/111 (24%), Positives = 53/111 (47%), Gaps = 6/111 (5%)
Frame = +2
Query: 233 NIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTW---LVSSERLWRPDVVLLNAAATT 403
+I E + + L+ W D+RLS+ + T+ LV +++W PD+ +++ +
Sbjct: 104 SISEVDMDFTMTLYLRHYWKDERLSFPSTNNLSMTFDGRLV--KKIWVPDMFFVHSKRSF 161
Query: 404 XGDYA---LRARVSNNGSVSWIKRLDISTPISMQLDNWPXDMQTCTFKFGS 547
D + RV +G V + R+ ++ +M +P D QTC+ + S
Sbjct: 162 IHDTTTDNVMLRVQPDGKVLYSLRVTVTAMCNMDFSRFPLDTQTCSLEIES 212
>BC096291-1|AAH96291.1| 556|Homo sapiens CHRNA4 protein protein.
Length = 556
Score = 34.3 bits (75), Expect = 0.54
Identities = 17/51 (33%), Positives = 27/51 (52%), Gaps = 4/51 (7%)
Frame = +2
Query: 407 GDYAL----RARVSNNGSVSWIKRLDISTPISMQLDNWPXDMQTCTFKFGS 547
GD+A+ +A + ++G V W + S+ + +P D Q CT KFGS
Sbjct: 60 GDFAVTHLTKAHLFHDGRVQWTPPAIYKSSCSIDVTFFPFDQQNCTMKFGS 110
>AB209359-1|BAD92596.1| 533|Homo sapiens cholinergic receptor,
nicotinic, alpha polypeptide 4 precursor variant
protein.
Length = 533
Score = 34.3 bits (75), Expect = 0.54
Identities = 17/51 (33%), Positives = 27/51 (52%), Gaps = 4/51 (7%)
Frame = +2
Query: 407 GDYAL----RARVSNNGSVSWIKRLDISTPISMQLDNWPXDMQTCTFKFGS 547
GD+A+ +A + ++G V W + S+ + +P D Q CT KFGS
Sbjct: 37 GDFAVTHLTKAHLFHDGRVQWTPPAIYKSSCSIDVTFFPFDQQNCTMKFGS 87
>U83981-1|AAC25631.1| 674|Homo sapiens apoptosis associated protein
protein.
Length = 674
Score = 31.1 bits (67), Expect = 5.1
Identities = 17/46 (36%), Positives = 22/46 (47%), Gaps = 1/46 (2%)
Frame = -1
Query: 434 IHGRGERSPRRWLQPRLAVPRQASTSVPRTPAKCCSP-TPLRSNSV 300
I+ GE+ P W PRL + Q P TP P TPL++ V
Sbjct: 511 IYVPGEKPPPPWAPPRLPLRLQRRLKRPETPTHDPDPETPLKARKV 556
>CR457259-1|CAG33540.1| 674|Homo sapiens PPP1R15A protein.
Length = 674
Score = 31.1 bits (67), Expect = 5.1
Identities = 17/46 (36%), Positives = 22/46 (47%), Gaps = 1/46 (2%)
Frame = -1
Query: 434 IHGRGERSPRRWLQPRLAVPRQASTSVPRTPAKCCSP-TPLRSNSV 300
I+ GE+ P W PRL + Q P TP P TPL++ V
Sbjct: 511 IYVPGEKPPPPWAPPRLPLRLQRRLKRPETPTHDPDPETPLKARKV 556
>BC003067-1|AAH03067.1| 674|Homo sapiens protein phosphatase 1,
regulatory (inhibitor) subunit 15A protein.
Length = 674
Score = 31.1 bits (67), Expect = 5.1
Identities = 17/46 (36%), Positives = 22/46 (47%), Gaps = 1/46 (2%)
Frame = -1
Query: 434 IHGRGERSPRRWLQPRLAVPRQASTSVPRTPAKCCSP-TPLRSNSV 300
I+ GE+ P W PRL + Q P TP P TPL++ V
Sbjct: 511 IYVPGEKPPPPWAPPRLPLRLQRRLKRPETPTHDPDPETPLKARKV 556
>AK001361-1|BAA91649.1| 674|Homo sapiens protein ( Homo sapiens
cDNA FLJ10499 fis, clone NT2RP2000346, weakly similar to
MYELOID DIFFERENTIATION PRIMARY RESPONSE PROTEIN MYD116.
).
Length = 674
Score = 31.1 bits (67), Expect = 5.1
Identities = 17/46 (36%), Positives = 22/46 (47%), Gaps = 1/46 (2%)
Frame = -1
Query: 434 IHGRGERSPRRWLQPRLAVPRQASTSVPRTPAKCCSP-TPLRSNSV 300
I+ GE+ P W PRL + Q P TP P TPL++ V
Sbjct: 511 IYVPGEKPPPPWAPPRLPLRLQRRLKRPETPTHDPDPETPLKARKV 556
>BC146774-1|AAI46775.1| 1114|Homo sapiens GPR124 protein protein.
Length = 1114
Score = 30.7 bits (66), Expect = 6.7
Identities = 16/55 (29%), Positives = 27/55 (49%), Gaps = 1/55 (1%)
Frame = +2
Query: 308 WNAGEWGCSTWLVSSERLWRPDVVLLNAAATTXGDYALRARVSNN-GSVSWIKRL 469
W +GEW C+ + + ++V+L +A+ Y RV+NN G W + L
Sbjct: 314 WASGEWECTVSMAQGNASKKVEIVVLETSAS----YCPAERVANNRGDFRWPRTL 364
>AY181242-1|AAO27354.1| 1331|Homo sapiens G protein-coupled receptor
124 protein.
Length = 1331
Score = 30.7 bits (66), Expect = 6.7
Identities = 16/55 (29%), Positives = 27/55 (49%), Gaps = 1/55 (1%)
Frame = +2
Query: 308 WNAGEWGCSTWLVSSERLWRPDVVLLNAAATTXGDYALRARVSNN-GSVSWIKRL 469
W +GEW C+ + + ++V+L +A+ Y RV+NN G W + L
Sbjct: 314 WASGEWECTVSMAQGNASKKVEIVVLETSAS----YCPAERVANNRGDFRWPRTL 364
>AK074099-1|BAB84925.1| 1310|Homo sapiens FLJ00170 protein protein.
Length = 1310
Score = 30.7 bits (66), Expect = 6.7
Identities = 16/55 (29%), Positives = 27/55 (49%), Gaps = 1/55 (1%)
Frame = +2
Query: 308 WNAGEWGCSTWLVSSERLWRPDVVLLNAAATTXGDYALRARVSNN-GSVSWIKRL 469
W +GEW C+ + + ++V+L +A+ Y RV+NN G W + L
Sbjct: 293 WASGEWECTVSMAQGNASKKVEIVVLETSAS----YCPAERVANNRGDFRWPRTL 343
>AF378755-1|AAL11992.1| 1331|Homo sapiens tumor endothelial marker 5
precursor protein.
Length = 1331
Score = 30.7 bits (66), Expect = 6.7
Identities = 16/55 (29%), Positives = 27/55 (49%), Gaps = 1/55 (1%)
Frame = +2
Query: 308 WNAGEWGCSTWLVSSERLWRPDVVLLNAAATTXGDYALRARVSNN-GSVSWIKRL 469
W +GEW C+ + + ++V+L +A+ Y RV+NN G W + L
Sbjct: 314 WASGEWECTVSMAQGNASKKVEIVVLETSAS----YCPAERVANNRGDFRWPRTL 364
>AB040964-1|BAA96055.2| 1206|Homo sapiens KIAA1531 protein protein.
Length = 1206
Score = 30.7 bits (66), Expect = 6.7
Identities = 16/55 (29%), Positives = 27/55 (49%), Gaps = 1/55 (1%)
Frame = +2
Query: 308 WNAGEWGCSTWLVSSERLWRPDVVLLNAAATTXGDYALRARVSNN-GSVSWIKRL 469
W +GEW C+ + + ++V+L +A+ Y RV+NN G W + L
Sbjct: 406 WASGEWECTVSMAQGNASKKVEIVVLETSAS----YCPAERVANNRGDFRWPRTL 456
>AK122582-1|BAC56923.1| 1383|Homo sapiens FLJ00269 protein protein.
Length = 1383
Score = 30.3 bits (65), Expect = 8.8
Identities = 13/38 (34%), Positives = 18/38 (47%)
Frame = -1
Query: 431 HGRGERSPRRWLQPRLAVPRQASTSVPRTPAKCCSPTP 318
HG + SP W Q + + P + P P +CCS P
Sbjct: 256 HGGRDCSPTCWEQGKCSGPAEQEKRGPSFPKECCSQGP 293
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 107,482,784
Number of Sequences: 237096
Number of extensions: 2352933
Number of successful extensions: 7104
Number of sequences better than 10.0: 213
Number of HSP's better than 10.0 without gapping: 5736
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 6935
length of database: 76,859,062
effective HSP length: 89
effective length of database: 55,757,518
effective search space used: 10315140830
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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