Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BmNP10_FL5_A04
(844 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
AJ306454-1|CAC34819.1| 497|Homo sapiens neuronal nicotinic acet... 65 3e-10
Y08416-1|CAA69693.1| 498|Homo sapiens nicotinic acetylcholine r... 63 1e-09
U62439-1|AAB40117.1| 498|Homo sapiens nicotinic acetylcholine r... 63 1e-09
U48861-1|AAA92123.1| 498|Homo sapiens beta 4 nicotinic acetylch... 63 1e-09
BC096082-1|AAH96082.1| 498|Homo sapiens cholinergic receptor, n... 63 1e-09
BC096080-1|AAH96080.1| 498|Homo sapiens cholinergic receptor, n... 63 1e-09
AF306329-1|AAL02062.1| 498|Homo sapiens neuronal nicotinic acet... 63 1e-09
Y08417-1|CAA69694.1| 458|Homo sapiens nicotinic acetylcholine r... 59 2e-08
X68275-1|CAA48336.1| 451|Homo sapiens nicotinic receptor beta 4... 59 2e-08
X67513-1|CAA47851.1| 423|Homo sapiens nicotinic acetylcholine ... 59 2e-08
X14830-1|CAA32939.1| 501|Homo sapiens protein ( Human mRNA for ... 59 2e-08
U62438-1|AAB40116.1| 458|Homo sapiens nicotinic acetylcholine r... 59 2e-08
BC069788-1|AAH69788.1| 458|Homo sapiens cholinergic receptor, n... 59 2e-08
BC069703-1|AAH69703.1| 458|Homo sapiens cholinergic receptor, n... 59 2e-08
BC069681-1|AAH69681.1| 458|Homo sapiens cholinergic receptor, n... 59 2e-08
BC011371-1|AAH11371.1| 501|Homo sapiens cholinergic receptor, n... 59 2e-08
AF140765-1|AAD33063.1| 458|Homo sapiens neuronal acetylcholine ... 59 2e-08
Y08419-1|CAA69696.1| 468|Homo sapiens nicotinic acetylcholine r... 58 3e-08
U62434-1|AAB40112.1| 468|Homo sapiens nicotinic acetylcholine r... 58 3e-08
BC033639-1|AAH33639.1| 468|Homo sapiens cholinergic receptor, n... 58 3e-08
AJ306481-1|CAC34820.1| 468|Homo sapiens neuronal nicotinic acet... 58 3e-08
Y16281-1|CAA76154.1| 529|Homo sapiens nicotinic acetylcholine r... 58 4e-08
Y08418-1|CAA69695.1| 503|Homo sapiens nicotinic acetylcholine r... 58 4e-08
X53559-1|CAA37625.1| 474|Homo sapiens neuronal nicotinic acetyl... 58 4e-08
U62432-1|AAB40110.1| 504|Homo sapiens nicotinic acetylcholine r... 58 4e-08
U62431-1|AAB40109.1| 529|Homo sapiens nicotinic acetylcholine r... 58 4e-08
M37981-1|AAA59942.1| 503|Homo sapiens neuronal nicotinic acetyl... 58 4e-08
BT006897-1|AAP35543.1| 505|Homo sapiens cholinergic receptor, n... 58 4e-08
BT006646-1|AAP35292.1| 489|Homo sapiens cholinergic receptor, n... 58 4e-08
BC098443-1|AAH98443.1| 504|Homo sapiens cholinergic receptor, n... 58 4e-08
BC023553-1|AAH23553.1| 501|Homo sapiens cholinergic receptor, n... 58 4e-08
BC006114-1|AAH06114.1| 489|Homo sapiens CHRNA3 protein protein. 58 4e-08
BC002996-1|AAH02996.1| 505|Homo sapiens cholinergic receptor, n... 58 4e-08
BC001642-1|AAH01642.1| 505|Homo sapiens cholinergic receptor, n... 58 4e-08
BC000513-1|AAH00513.1| 505|Homo sapiens cholinergic receptor, n... 58 4e-08
AJ007783-1|CAA07682.1| 504|Homo sapiens nicotinic acetylcholine... 58 4e-08
AF385584-1|AAK68110.1| 489|Homo sapiens nicotinic cholinergic r... 58 4e-08
Y16282-1|CAA76155.1| 494|Homo sapiens nicotinic acetylcholine r... 58 5e-08
U62435-1|AAB40113.1| 494|Homo sapiens nicotinic acetylcholine r... 58 5e-08
BC014456-1|AAH14456.1| 494|Homo sapiens cholinergic receptor, n... 58 5e-08
AB079251-1|BAC06855.1| 494|Homo sapiens Nicotinic acetylcholine... 58 5e-08
X66403-1|CAA47030.1| 493|Homo sapiens acetylcholine receptor ep... 57 7e-08
M83712-1|AAA58357.1| 468|Homo sapiens nicotinic receptor alpha ... 57 7e-08
AF105999-1|AAD24503.1| 493|Homo sapiens acetylcholine receptor ... 57 7e-08
M86383-1|AAC84176.1| 502|Homo sapiens nicotinic acetylcholine r... 56 2e-07
Y08421-1|CAA69698.1| 627|Homo sapiens nicotinic acetylcholine r... 55 3e-07
X89741-1|CAA61893.1| 627|Homo sapiens neuronal acetylcholine re... 55 3e-07
X87629-1|CAA60959.1| 602|Homo sapiens nicotinic acetylcholine r... 55 3e-07
U62433-1|AAB40111.1| 627|Homo sapiens nicotinic acetylcholine r... 55 3e-07
L35901-1|AAA64743.1| 627|Homo sapiens nicotinic acetylcholine r... 55 3e-07
DQ093071-1|AAY88737.1| 627|Homo sapiens cholinergic receptor, n... 55 3e-07
BC096290-1|AAH96290.1| 627|Homo sapiens cholinergic receptor, n... 55 3e-07
X01715-1|CAA25861.1| 520|Homo sapiens acetylcholine receptor ga... 55 4e-07
AC092165-3|AAY24103.1| 520|Homo sapiens unknown protein. 55 4e-07
Y00762-1|CAA68731.1| 457|Homo sapiens protein ( Human mRNA for ... 54 6e-07
X02502-1|CAA26344.1| 457|Homo sapiens acetylcholine receptor pr... 54 6e-07
S77094-1|AAD14247.1| 457|Homo sapiens nicotinic acetylcholine r... 54 6e-07
BC006314-1|AAH06314.1| 269|Homo sapiens CHRNA1 protein protein. 54 6e-07
AJ295237-1|CAC16144.1| 450|Homo sapiens neuronal nicotinic acet... 54 6e-07
AJ278118-1|CAC20435.1| 450|Homo sapiens neuronal nicotinic acet... 54 6e-07
AF327367-1|AAK14333.1| 450|Homo sapiens nicotinic acetylcholine... 54 6e-07
AF199235-1|AAG00795.2| 450|Homo sapiens nicotinic acetylcholine... 54 6e-07
AC018890-1|AAY14687.1| 457|Homo sapiens unknown protein. 54 6e-07
BC113575-1|AAI13576.1| 479|Homo sapiens cholinergic receptor, n... 53 1e-06
BC113549-1|AAI13550.1| 479|Homo sapiens cholinergic receptor, n... 53 1e-06
AY123244-1|AAM74523.1| 479|Homo sapiens nicotinic acetylcholine... 53 1e-06
AJ243342-1|CAB65091.1| 479|Homo sapiens nicotinic acetylcholine... 53 1e-06
AF227732-1|AAF61920.1| 470|Homo sapiens nicotinic acetylcholine... 53 1e-06
AC118275-1|AAY40986.1| 479|Homo sapiens unknown protein. 53 1e-06
Y08415-1|CAA69692.1| 502|Homo sapiens nicotinic acetylcholine r... 52 3e-06
X53179-1|CAA37320.1| 502|Homo sapiens precursor peptide (AA -25... 52 3e-06
U62437-1|AAB40115.1| 502|Homo sapiens nicotinic acetylcholine r... 52 3e-06
BC075041-1|AAH75041.1| 502|Homo sapiens cholinergic receptor, n... 52 3e-06
BC075040-1|AAH75040.1| 502|Homo sapiens cholinergic receptor, n... 52 3e-06
AL592078-3|CAI16184.1| 502|Homo sapiens cholinergic receptor, n... 52 3e-06
AJ001935-1|CAA05108.1| 504|Homo sapiens CHRNB2 protein. 52 3e-06
AF077186-1|AAD45422.1| 502|Homo sapiens neuronal nicotinic acet... 52 3e-06
X55019-1|CAA38759.1| 517|Homo sapiens acetylcholine receptor de... 50 8e-06
DQ644022-1|ABG35128.1| 456|Homo sapiens 5-HT3 receptor subunit ... 50 8e-06
BC101185-1|AAI01186.1| 374|Homo sapiens HTR3E protein protein. 50 8e-06
BC101183-1|AAI01184.1| 471|Homo sapiens 5-hydroxytryptamine (se... 50 8e-06
BC101182-1|AAI01183.1| 471|Homo sapiens 5-hydroxytryptamine (se... 50 8e-06
BC093925-1|AAH93925.1| 517|Homo sapiens cholinergic receptor, n... 50 8e-06
BC093923-1|AAH93923.1| 517|Homo sapiens cholinergic receptor, n... 50 8e-06
AY159813-1|AAO38167.2| 471|Homo sapiens 5-hydroxytryptamine ser... 50 8e-06
AC092165-2|AAY24102.1| 517|Homo sapiens unknown protein. 50 8e-06
BC111802-1|AAI11803.1| 465|Homo sapiens CHRNG protein protein. 50 1e-05
M59216-1|AAA35862.1| 474|Homo sapiens gamma-aminobutyric acid r... 49 2e-05
S77554-1|AAB33983.1| 474|Homo sapiens GABAA receptor beta 2 sub... 49 2e-05
S77553-1|AAB33982.1| 512|Homo sapiens GABAA receptor beta 2 sub... 49 2e-05
S67368-1|AAB29370.1| 474|Homo sapiens gamma-aminobutyric acid A... 49 2e-05
BC131799-1|AAI31800.1| 447|Homo sapiens 5-hydroxytryptamine (se... 49 2e-05
BC110597-1|AAI10598.1| 411|Homo sapiens ligand-gated ion channe... 49 2e-05
BC105639-1|AAI05640.1| 474|Homo sapiens GABRB2 protein protein. 49 2e-05
BC099719-1|AAH99719.1| 474|Homo sapiens GABRB2 protein protein. 49 2e-05
BC099705-1|AAH99705.1| 474|Homo sapiens GABRB2 protein protein. 49 2e-05
AF512521-1|AAO20969.1| 411|Homo sapiens ligand-gated ion channe... 49 2e-05
X14767-1|CAA32875.1| 474|Homo sapiens GABA-A receptor beta 1 su... 48 3e-05
AY349353-1|AAQ93477.1| 456|Homo sapiens 5-HT3c1 serotonin recep... 48 3e-05
AY349352-1|AAQ93476.1| 441|Homo sapiens 5-HT3c1 serotonin recep... 48 3e-05
AF459285-1|AAL66182.1| 447|Homo sapiens 5-hydroxytryptamine rec... 48 3e-05
AB223030-1|BAE19924.1| 411|Homo sapiens ligand-gated ion-channe... 48 3e-05
U77731-2|AAB38273.1| 360|Homo sapiens glycine receptor alpha 2B... 46 1e-04
CR450343-1|CAG29339.1| 452|Homo sapiens GLRA2 protein. 46 1e-04
BC096083-1|AAH96083.1| 198|Homo sapiens CHRNB4 protein protein. 46 1e-04
BC096081-1|AAH96081.1| 198|Homo sapiens CHRNB4 protein protein. 46 1e-04
AY437084-1|AAR87843.1| 452|Homo sapiens glycine receptor alpha2... 46 1e-04
X52008-1|CAA36257.1| 452|Homo sapiens inhibitory glycine recept... 46 2e-04
U77731-1|AAB38272.1| 360|Homo sapiens glycine receptor alpha 2 ... 46 2e-04
BC032864-1|AAH32864.1| 452|Homo sapiens glycine receptor, alpha... 46 2e-04
AY437083-1|AAR87842.1| 452|Homo sapiens glycine receptor alpha2... 46 2e-04
AF053495-1|AAC35290.1| 452|Homo sapiens glycine receptor alpha ... 46 2e-04
Z23141-1|CAA80672.1| 479|Homo sapiens cholinergic receptor, nic... 46 2e-04
Y08420-1|CAA69697.1| 502|Homo sapiens nicotinic acetylcholine r... 46 2e-04
X70297-1|CAA49778.1| 502|Homo sapiens neuronal nicotinic acetyl... 46 2e-04
U62436-1|AAB40114.1| 502|Homo sapiens nicotinic acetylcholine r... 46 2e-04
AJ586911-1|CAE52911.1| 502|Homo sapiens nicotinic acetylcholine... 46 2e-04
AK122638-1|BAC85499.1| 266|Homo sapiens yte protein of 76kDa) (... 45 3e-04
U40583-1|AAA83561.1| 502|Homo sapiens alpha 7 neuronal nicotini... 44 5e-04
AF385585-1|AAK68111.1| 502|Homo sapiens nicotinic cholinergic r... 44 5e-04
BC022449-1|AAH22449.1| 474|Homo sapiens gamma-aminobutyric acid... 44 7e-04
AJ003080-1|CAA05853.1| 238|Homo sapiens serotonin receptor prot... 44 7e-04
BC109211-1|AAI09212.1| 632|Homo sapiens gamma-aminobutyric acid... 44 0.001
BC109210-1|AAI09211.1| 632|Homo sapiens gamma-aminobutyric acid... 44 0.001
AF189259-1|AAF70380.1| 632|Homo sapiens GABA-A receptor theta s... 44 0.001
AF144648-1|AAD51172.1| 627|Homo sapiens GABA-A receptor theta p... 44 0.001
U95367-1|AAC51357.1| 440|Homo sapiens GABA-A receptor pi subuni... 43 0.001
BC109106-1|AAI09107.1| 440|Homo sapiens gamma-aminobutyric acid... 43 0.001
BC109105-1|AAI09106.1| 440|Homo sapiens gamma-aminobutyric acid... 43 0.001
BC074865-1|AAH74865.1| 440|Homo sapiens gamma-aminobutyric acid... 43 0.001
BC074810-1|AAH74810.1| 440|Homo sapiens gamma-aminobutyric acid... 43 0.001
BC033801-1|AAH33801.1| 452|Homo sapiens gamma-aminobutyric acid... 43 0.001
AL391845-4|CAI15436.1| 452|Homo sapiens gamma-aminobutyric acid... 43 0.001
AF016917-1|AAB70007.1| 452|Homo sapiens GABA-A receptor delta s... 43 0.001
AF009702-1|AAC24194.1| 440|Homo sapiens GABA-A receptor pi subu... 43 0.001
X52009-1|CAA36258.1| 449|Homo sapiens inhibitory glycine recept... 41 0.005
BC114947-1|AAI14948.1| 457|Homo sapiens GLRA1 protein protein. 41 0.005
BC074980-1|AAH74980.1| 449|Homo sapiens glycine receptor, alpha... 41 0.005
U93917-1|AAC39917.1| 449|Homo sapiens glycine receptor alpha 3 ... 40 0.009
BC036086-1|AAH36086.1| 464|Homo sapiens glycine receptor, alpha... 40 0.009
AF017724-1|AAC39919.1| 465|Homo sapiens glycine receptor alpha ... 40 0.009
Z93848-1|CAI41994.1| 376|Homo sapiens glycine receptor, alpha 4... 40 0.011
AL049610-1|CAI42158.1| 376|Homo sapiens glycine receptor, alpha... 40 0.011
BC114967-1|AAI14968.1| 366|Homo sapiens GLRA1 protein protein. 39 0.026
BC146774-1|AAI46775.1| 1114|Homo sapiens GPR124 protein protein. 31 6.9
AY181242-1|AAO27354.1| 1331|Homo sapiens G protein-coupled recep... 31 6.9
AK074099-1|BAB84925.1| 1310|Homo sapiens FLJ00170 protein protein. 31 6.9
AF378755-1|AAL11992.1| 1331|Homo sapiens tumor endothelial marke... 31 6.9
AB040964-1|BAA96055.2| 1206|Homo sapiens KIAA1531 protein protein. 31 6.9
AB209359-1|BAD92596.1| 533|Homo sapiens cholinergic receptor, n... 30 9.1
>AJ306454-1|CAC34819.1| 497|Homo sapiens neuronal nicotinic
acetylcholine receptor beta-4 subunit protein.
Length = 497
Score = 65.3 bits (152), Expect = 3e-10
Identities = 44/168 (26%), Positives = 76/168 (45%), Gaps = 8/168 (4%)
Frame = +1
Query: 61 AIASAAECENATSLSLMIDSLL--ATYDRESPP--DSKIVVNLTLHLRHA---NIRESES 219
A+ C A + ++D LL Y+ P S ++++ L L A ++ E E
Sbjct: 14 ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQ 73
Query: 220 TVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRAR 396
+ L+ W D RL+WN+ + G + + ++R+W PD+VL N T
Sbjct: 74 IMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNDGTYEVSVYTNLI 133
Query: 397 VSNNGSVSWIKRLDISTPISMQLDNWXNDMQTCTFKXGSRMHNSDEMD 540
V +NGSV W+ + +++ + D Q CT K S ++ E+D
Sbjct: 134 VRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRSWTYDHTEID 181
>Y08416-1|CAA69693.1| 498|Homo sapiens nicotinic acetylcholine
receptor beta4 subunit precursor protein.
Length = 498
Score = 63.3 bits (147), Expect = 1e-09
Identities = 45/169 (26%), Positives = 77/169 (45%), Gaps = 9/169 (5%)
Frame = +1
Query: 61 AIASAAECENATSLSLMIDSLL--ATYDRESPP--DSKIVVNLTLHLRHA---NIRESES 219
A+ C A + ++D LL Y+ P S ++++ L L A ++ E E
Sbjct: 14 ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQ 73
Query: 220 TVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRA 393
+ L+ W D RL+WN+ + G + + ++R+W PD+VL N A T
Sbjct: 74 IMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNADGTYEVSVYTNL 133
Query: 394 RVSNNGSVSWIKRLDISTPISMQLDNWXNDMQTCTFKXGSRMHNSDEMD 540
V +NGSV W+ + +++ + D Q CT K S ++ E+D
Sbjct: 134 IVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRSWTYDHTEID 182
>U62439-1|AAB40117.1| 498|Homo sapiens nicotinic acetylcholine
receptor beta4 subunit precursor protein.
Length = 498
Score = 63.3 bits (147), Expect = 1e-09
Identities = 45/169 (26%), Positives = 77/169 (45%), Gaps = 9/169 (5%)
Frame = +1
Query: 61 AIASAAECENATSLSLMIDSLL--ATYDRESPP--DSKIVVNLTLHLRHA---NIRESES 219
A+ C A + ++D LL Y+ P S ++++ L L A ++ E E
Sbjct: 14 ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQ 73
Query: 220 TVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRA 393
+ L+ W D RL+WN+ + G + + ++R+W PD+VL N A T
Sbjct: 74 IMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNADGTYEVSVYTNL 133
Query: 394 RVSNNGSVSWIKRLDISTPISMQLDNWXNDMQTCTFKXGSRMHNSDEMD 540
V +NGSV W+ + +++ + D Q CT K S ++ E+D
Sbjct: 134 IVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRSWTYDHTEID 182
>U48861-1|AAA92123.1| 498|Homo sapiens beta 4 nicotinic
acetylcholine receptor subunit protein.
Length = 498
Score = 63.3 bits (147), Expect = 1e-09
Identities = 45/169 (26%), Positives = 77/169 (45%), Gaps = 9/169 (5%)
Frame = +1
Query: 61 AIASAAECENATSLSLMIDSLL--ATYDRESPP--DSKIVVNLTLHLRHA---NIRESES 219
A+ C A + ++D LL Y+ P S ++++ L L A ++ E E
Sbjct: 14 ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQ 73
Query: 220 TVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRA 393
+ L+ W D RL+WN+ + G + + ++R+W PD+VL N A T
Sbjct: 74 IMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNADGTYEVSVYTNL 133
Query: 394 RVSNNGSVSWIKRLDISTPISMQLDNWXNDMQTCTFKXGSRMHNSDEMD 540
V +NGSV W+ + +++ + D Q CT K S ++ E+D
Sbjct: 134 IVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRSWTYDHTEID 182
>BC096082-1|AAH96082.1| 498|Homo sapiens cholinergic receptor,
nicotinic, beta 4 protein.
Length = 498
Score = 63.3 bits (147), Expect = 1e-09
Identities = 45/169 (26%), Positives = 77/169 (45%), Gaps = 9/169 (5%)
Frame = +1
Query: 61 AIASAAECENATSLSLMIDSLL--ATYDRESPP--DSKIVVNLTLHLRHA---NIRESES 219
A+ C A + ++D LL Y+ P S ++++ L L A ++ E E
Sbjct: 14 ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQ 73
Query: 220 TVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRA 393
+ L+ W D RL+WN+ + G + + ++R+W PD+VL N A T
Sbjct: 74 IMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNADGTYEVSVYTNL 133
Query: 394 RVSNNGSVSWIKRLDISTPISMQLDNWXNDMQTCTFKXGSRMHNSDEMD 540
V +NGSV W+ + +++ + D Q CT K S ++ E+D
Sbjct: 134 IVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRSWTYDHTEID 182
>BC096080-1|AAH96080.1| 498|Homo sapiens cholinergic receptor,
nicotinic, beta 4 protein.
Length = 498
Score = 63.3 bits (147), Expect = 1e-09
Identities = 45/169 (26%), Positives = 77/169 (45%), Gaps = 9/169 (5%)
Frame = +1
Query: 61 AIASAAECENATSLSLMIDSLL--ATYDRESPP--DSKIVVNLTLHLRHA---NIRESES 219
A+ C A + ++D LL Y+ P S ++++ L L A ++ E E
Sbjct: 14 ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQ 73
Query: 220 TVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRA 393
+ L+ W D RL+WN+ + G + + ++R+W PD+VL N A T
Sbjct: 74 IMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNADGTYEVSVYTNL 133
Query: 394 RVSNNGSVSWIKRLDISTPISMQLDNWXNDMQTCTFKXGSRMHNSDEMD 540
V +NGSV W+ + +++ + D Q CT K S ++ E+D
Sbjct: 134 IVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRSWTYDHTEID 182
>AF306329-1|AAL02062.1| 498|Homo sapiens neuronal nicotinic
acetylcholine receptor beta 4 subunit protein.
Length = 498
Score = 63.3 bits (147), Expect = 1e-09
Identities = 45/169 (26%), Positives = 77/169 (45%), Gaps = 9/169 (5%)
Frame = +1
Query: 61 AIASAAECENATSLSLMIDSLL--ATYDRESPP--DSKIVVNLTLHLRHA---NIRESES 219
A+ C A + ++D LL Y+ P S ++++ L L A ++ E E
Sbjct: 14 ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQ 73
Query: 220 TVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRA 393
+ L+ W D RL+WN+ + G + + ++R+W PD+VL N A T
Sbjct: 74 IMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNADGTYEVSVYTNL 133
Query: 394 RVSNNGSVSWIKRLDISTPISMQLDNWXNDMQTCTFKXGSRMHNSDEMD 540
V +NGSV W+ + +++ + D Q CT K S ++ E+D
Sbjct: 134 IVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRSWTYDHTEID 182
>Y08417-1|CAA69694.1| 458|Homo sapiens nicotinic acetylcholine
receptor beta3 subunit precursor protein.
Length = 458
Score = 59.3 bits (137), Expect = 2e-08
Identities = 32/102 (31%), Positives = 49/102 (48%), Gaps = 2/102 (1%)
Frame = +1
Query: 241 LQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLL-NAAATTAGDYALRARVSNNGS 414
L+ W D +L WN ++G + V SE LW PD+VL NA G + V +NG+
Sbjct: 81 LKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFEGSLMTKVIVKSNGT 140
Query: 415 VSWIKRLDISTPISMQLDNWXNDMQTCTFKXGSRMHNSDEMD 540
V W + +M + + D Q C+ K GS ++ +D
Sbjct: 141 VVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGTMVD 182
>X68275-1|CAA48336.1| 451|Homo sapiens nicotinic receptor beta 4
subunit protein.
Length = 451
Score = 59.3 bits (137), Expect = 2e-08
Identities = 36/129 (27%), Positives = 61/129 (47%), Gaps = 3/129 (2%)
Frame = +1
Query: 163 IVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 336
I + L L L ++ E + + L+ W D RL+WN+ + G + + ++R+W P
Sbjct: 7 ISIKLQLSLAQLISVNERDEIMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLP 66
Query: 337 DVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWXNDMQTCTFKXGS 513
D+VL N A T V +NGSV W+ + +++ + D Q CT K S
Sbjct: 67 DIVLYNNADGTYEVSVYTNLIVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRS 126
Query: 514 RMHNSDEMD 540
++ E+D
Sbjct: 127 WTYDHTEID 135
>X67513-1|CAA47851.1| 423|Homo sapiens nicotinic acetylcholine
receptor beta-3 subunit protein.
Length = 423
Score = 59.3 bits (137), Expect = 2e-08
Identities = 32/102 (31%), Positives = 49/102 (48%), Gaps = 2/102 (1%)
Frame = +1
Query: 241 LQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLL-NAAATTAGDYALRARVSNNGS 414
L+ W D +L WN ++G + V SE LW PD+VL NA G + V +NG+
Sbjct: 46 LKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFEGSLMTKVIVKSNGT 105
Query: 415 VSWIKRLDISTPISMQLDNWXNDMQTCTFKXGSRMHNSDEMD 540
V W + +M + + D Q C+ K GS ++ +D
Sbjct: 106 VVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGTMVD 147
>X14830-1|CAA32939.1| 501|Homo sapiens protein ( Human mRNA for
muscle acetylcholine receptor beta-subunit. ).
Length = 501
Score = 59.3 bits (137), Expect = 2e-08
Identities = 45/140 (32%), Positives = 69/140 (49%), Gaps = 4/140 (2%)
Frame = +1
Query: 139 RESPPDSKIVVNLTL-HLRHANIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLV 312
RE ++ V L L L N ++ E + ++ DL+ W D RLSW+ E G + +
Sbjct: 46 REVGDRVRVSVGLILAQLISLNEKDEEMSTKVYLDLE--WTDYRLSWDPAEHDGIDSLRI 103
Query: 313 SSERLWRPDVVLLNAAATTAGDYAL--RARVSNNGSVSWIKRLDISTPISMQLDNWXNDM 486
++E +W PDVVLLN D AL VS++GSV W + S+Q+ + D
Sbjct: 104 TAESVWLPDVVLLNNNDGNF-DVALDISVVVSSDGSVRWQPPGIYRSSCSIQVTYFPFDW 162
Query: 487 QTCTFKXGSRMHNSDEMDFR 546
Q CT S ++S E+ +
Sbjct: 163 QNCTMVFSSYSYDSSEVSLQ 182
>U62438-1|AAB40116.1| 458|Homo sapiens nicotinic acetylcholine
receptor beta3 subunit precursor protein.
Length = 458
Score = 59.3 bits (137), Expect = 2e-08
Identities = 32/102 (31%), Positives = 49/102 (48%), Gaps = 2/102 (1%)
Frame = +1
Query: 241 LQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLL-NAAATTAGDYALRARVSNNGS 414
L+ W D +L WN ++G + V SE LW PD+VL NA G + V +NG+
Sbjct: 81 LKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFEGSLMTKVIVKSNGT 140
Query: 415 VSWIKRLDISTPISMQLDNWXNDMQTCTFKXGSRMHNSDEMD 540
V W + +M + + D Q C+ K GS ++ +D
Sbjct: 141 VVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGTMVD 182
>BC069788-1|AAH69788.1| 458|Homo sapiens cholinergic receptor,
nicotinic, beta 3 protein.
Length = 458
Score = 59.3 bits (137), Expect = 2e-08
Identities = 32/102 (31%), Positives = 49/102 (48%), Gaps = 2/102 (1%)
Frame = +1
Query: 241 LQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLL-NAAATTAGDYALRARVSNNGS 414
L+ W D +L WN ++G + V SE LW PD+VL NA G + V +NG+
Sbjct: 81 LKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFEGSLMTKVIVKSNGT 140
Query: 415 VSWIKRLDISTPISMQLDNWXNDMQTCTFKXGSRMHNSDEMD 540
V W + +M + + D Q C+ K GS ++ +D
Sbjct: 141 VVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGTMVD 182
>BC069703-1|AAH69703.1| 458|Homo sapiens cholinergic receptor,
nicotinic, beta 3 protein.
Length = 458
Score = 59.3 bits (137), Expect = 2e-08
Identities = 32/102 (31%), Positives = 49/102 (48%), Gaps = 2/102 (1%)
Frame = +1
Query: 241 LQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLL-NAAATTAGDYALRARVSNNGS 414
L+ W D +L WN ++G + V SE LW PD+VL NA G + V +NG+
Sbjct: 81 LKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFEGSLMTKVIVKSNGT 140
Query: 415 VSWIKRLDISTPISMQLDNWXNDMQTCTFKXGSRMHNSDEMD 540
V W + +M + + D Q C+ K GS ++ +D
Sbjct: 141 VVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGTMVD 182
>BC069681-1|AAH69681.1| 458|Homo sapiens cholinergic receptor,
nicotinic, beta 3 protein.
Length = 458
Score = 59.3 bits (137), Expect = 2e-08
Identities = 32/102 (31%), Positives = 49/102 (48%), Gaps = 2/102 (1%)
Frame = +1
Query: 241 LQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLL-NAAATTAGDYALRARVSNNGS 414
L+ W D +L WN ++G + V SE LW PD+VL NA G + V +NG+
Sbjct: 81 LKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFEGSLMTKVIVKSNGT 140
Query: 415 VSWIKRLDISTPISMQLDNWXNDMQTCTFKXGSRMHNSDEMD 540
V W + +M + + D Q C+ K GS ++ +D
Sbjct: 141 VVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGTMVD 182
>BC011371-1|AAH11371.1| 501|Homo sapiens cholinergic receptor,
nicotinic, beta 1 (muscle) protein.
Length = 501
Score = 59.3 bits (137), Expect = 2e-08
Identities = 45/140 (32%), Positives = 69/140 (49%), Gaps = 4/140 (2%)
Frame = +1
Query: 139 RESPPDSKIVVNLTL-HLRHANIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLV 312
RE ++ V L L L N ++ E + ++ DL+ W D RLSW+ E G + +
Sbjct: 46 REVGDRVRVSVGLILAQLISLNEKDEEMSTKVYLDLE--WTDYRLSWDPAEHDGIDSLRI 103
Query: 313 SSERLWRPDVVLLNAAATTAGDYAL--RARVSNNGSVSWIKRLDISTPISMQLDNWXNDM 486
++E +W PDVVLLN D AL VS++GSV W + S+Q+ + D
Sbjct: 104 TAESVWLPDVVLLNNNDGNF-DVALDISVVVSSDGSVRWQPPGIYRSSCSIQVTYFPFDW 162
Query: 487 QTCTFKXGSRMHNSDEMDFR 546
Q CT S ++S E+ +
Sbjct: 163 QNCTMVFSSYSYDSSEVSLQ 182
>AF140765-1|AAD33063.1| 458|Homo sapiens neuronal acetylcholine
receptor beta-3 subunit precursor protein.
Length = 458
Score = 59.3 bits (137), Expect = 2e-08
Identities = 32/102 (31%), Positives = 49/102 (48%), Gaps = 2/102 (1%)
Frame = +1
Query: 241 LQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLL-NAAATTAGDYALRARVSNNGS 414
L+ W D +L WN ++G + V SE LW PD+VL NA G + V +NG+
Sbjct: 81 LKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFEGSLMTKVIVKSNGT 140
Query: 415 VSWIKRLDISTPISMQLDNWXNDMQTCTFKXGSRMHNSDEMD 540
V W + +M + + D Q C+ K GS ++ +D
Sbjct: 141 VVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGTMVD 182
>Y08419-1|CAA69696.1| 468|Homo sapiens nicotinic acetylcholine
receptor alpha5 subunit precursor protein.
Length = 468
Score = 58.4 bits (135), Expect = 3e-08
Identities = 35/150 (23%), Positives = 69/150 (46%), Gaps = 6/150 (4%)
Frame = +1
Query: 109 MIDSLLATYDRESPP----DSKIVVNLTLHLRH-ANIRESESTVRILADLQMNWIDKRLS 273
++ L Y+R P + KI + L + ++ E + L+ WID +L
Sbjct: 50 LLKDLFQDYERWVRPVEHLNDKIKIKFGLAISQLVDVDEKNQLMTTNVWLKQEWIDVKLR 109
Query: 274 WNAGEWG-CSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVSWIKRLDISTP 450
WN ++G V S+ +W PD+VL + A + + + NG+V+W + +
Sbjct: 110 WNPDDYGGIKVIRVPSDSVWTPDIVLFDNADGRFEGTSTKTVIRYNGTVTWTPPANYKSS 169
Query: 451 ISMQLDNWXNDMQTCTFKXGSRMHNSDEMD 540
++ + + D+Q C+ K GS ++ ++D
Sbjct: 170 CTIDVTFFPFDLQNCSMKFGSWTYDGSQVD 199
>U62434-1|AAB40112.1| 468|Homo sapiens nicotinic acetylcholine
receptor alpha5 subunit precursor protein.
Length = 468
Score = 58.4 bits (135), Expect = 3e-08
Identities = 35/150 (23%), Positives = 69/150 (46%), Gaps = 6/150 (4%)
Frame = +1
Query: 109 MIDSLLATYDRESPP----DSKIVVNLTLHLRH-ANIRESESTVRILADLQMNWIDKRLS 273
++ L Y+R P + KI + L + ++ E + L+ WID +L
Sbjct: 50 LLKDLFQDYERWVRPVEHLNDKIKIKFGLAISQLVDVDEKNQLMTTNVWLKQEWIDVKLR 109
Query: 274 WNAGEWG-CSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVSWIKRLDISTP 450
WN ++G V S+ +W PD+VL + A + + + NG+V+W + +
Sbjct: 110 WNPDDYGGIKVIRVPSDSVWTPDIVLFDNADGRFEGTSTKTVIRYNGTVTWTPPANYKSS 169
Query: 451 ISMQLDNWXNDMQTCTFKXGSRMHNSDEMD 540
++ + + D+Q C+ K GS ++ ++D
Sbjct: 170 CTIDVTFFPFDLQNCSMKFGSWTYDGSQVD 199
>BC033639-1|AAH33639.1| 468|Homo sapiens cholinergic receptor,
nicotinic, alpha 5 protein.
Length = 468
Score = 58.4 bits (135), Expect = 3e-08
Identities = 35/150 (23%), Positives = 69/150 (46%), Gaps = 6/150 (4%)
Frame = +1
Query: 109 MIDSLLATYDRESPP----DSKIVVNLTLHLRH-ANIRESESTVRILADLQMNWIDKRLS 273
++ L Y+R P + KI + L + ++ E + L+ WID +L
Sbjct: 50 LLKDLFQDYERWVRPVEHLNDKIKIKFGLAISQLVDVDEKNQLMTTNVWLKQEWIDVKLR 109
Query: 274 WNAGEWG-CSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVSWIKRLDISTP 450
WN ++G V S+ +W PD+VL + A + + + NG+V+W + +
Sbjct: 110 WNPDDYGGIKVIRVPSDSVWTPDIVLFDNADGRFEGTSTKTVIRYNGTVTWTPPANYKSS 169
Query: 451 ISMQLDNWXNDMQTCTFKXGSRMHNSDEMD 540
++ + + D+Q C+ K GS ++ ++D
Sbjct: 170 CTIDVTFFPFDLQNCSMKFGSWTYDGSQVD 199
>AJ306481-1|CAC34820.1| 468|Homo sapiens neuronal nicotinic
acetylcholine receptor alpha-5subunit protein.
Length = 468
Score = 58.4 bits (135), Expect = 3e-08
Identities = 35/150 (23%), Positives = 69/150 (46%), Gaps = 6/150 (4%)
Frame = +1
Query: 109 MIDSLLATYDRESPP----DSKIVVNLTLHLRH-ANIRESESTVRILADLQMNWIDKRLS 273
++ L Y+R P + KI + L + ++ E + L+ WID +L
Sbjct: 50 LLKDLFQDYERWVRPVEHLNDKIKIKFGLAISQLVDVDEKNQLMTTNVWLKQEWIDVKLR 109
Query: 274 WNAGEWG-CSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVSWIKRLDISTP 450
WN ++G V S+ +W PD+VL + A + + + NG+V+W + +
Sbjct: 110 WNPDDYGGIKVIRVPSDSVWTPDIVLFDNADGRFEGTSTKTVIRYNGTVTWTPPANYKSS 169
Query: 451 ISMQLDNWXNDMQTCTFKXGSRMHNSDEMD 540
++ + + D+Q C+ K GS ++ ++D
Sbjct: 170 CTIDVTFFPFDLQNCSMKFGSWTYDGSQVD 199
>Y16281-1|CAA76154.1| 529|Homo sapiens nicotinic acetylcholine
receptor alpha2 subunit precursor protein.
Length = 529
Score = 58.0 bits (134), Expect = 4e-08
Identities = 32/102 (31%), Positives = 52/102 (50%), Gaps = 2/102 (1%)
Frame = +1
Query: 241 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAA-ATTAGDYALRARVSNNGS 414
L+ W D +L WN ++G T L V SE +W PD+VL N A A + +A + + G+
Sbjct: 111 LKQEWSDYKLRWNPADFGNITSLRVPSEMIWIPDIVLYNNADGEFAVTHMTKAHLFSTGT 170
Query: 415 VSWIKRLDISTPISMQLDNWXNDMQTCTFKXGSRMHNSDEMD 540
V W+ + S+ + + D Q C K GS ++ ++D
Sbjct: 171 VHWVPPAIYKSSCSIDVTFFPFDQQNCKMKFGSWTYDKAKID 212
>Y08418-1|CAA69695.1| 503|Homo sapiens nicotinic acetylcholine
receptor alpha3 subunit precursor protein.
Length = 503
Score = 58.0 bits (134), Expect = 4e-08
Identities = 29/102 (28%), Positives = 53/102 (51%), Gaps = 2/102 (1%)
Frame = +1
Query: 241 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 414
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 85 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 144
Query: 415 VSWIKRLDISTPISMQLDNWXNDMQTCTFKXGSRMHNSDEMD 540
V+WI + + + + D Q CT K GS ++ ++D
Sbjct: 145 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKID 186
>X53559-1|CAA37625.1| 474|Homo sapiens neuronal nicotinic
acetylcholine receptor alpha-3merase protein.
Length = 474
Score = 58.0 bits (134), Expect = 4e-08
Identities = 29/102 (28%), Positives = 53/102 (51%), Gaps = 2/102 (1%)
Frame = +1
Query: 241 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 414
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 56 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 115
Query: 415 VSWIKRLDISTPISMQLDNWXNDMQTCTFKXGSRMHNSDEMD 540
V+WI + + + + D Q CT K GS ++ ++D
Sbjct: 116 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKID 157
>U62432-1|AAB40110.1| 504|Homo sapiens nicotinic acetylcholine
receptor alpha3 subunit precursor protein.
Length = 504
Score = 58.0 bits (134), Expect = 4e-08
Identities = 29/102 (28%), Positives = 53/102 (51%), Gaps = 2/102 (1%)
Frame = +1
Query: 241 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 414
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 86 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 145
Query: 415 VSWIKRLDISTPISMQLDNWXNDMQTCTFKXGSRMHNSDEMD 540
V+WI + + + + D Q CT K GS ++ ++D
Sbjct: 146 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKID 187
>U62431-1|AAB40109.1| 529|Homo sapiens nicotinic acetylcholine
receptor alpha2 subunit precursor protein.
Length = 529
Score = 58.0 bits (134), Expect = 4e-08
Identities = 32/102 (31%), Positives = 52/102 (50%), Gaps = 2/102 (1%)
Frame = +1
Query: 241 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAA-ATTAGDYALRARVSNNGS 414
L+ W D +L WN ++G T L V SE +W PD+VL N A A + +A + + G+
Sbjct: 111 LKQEWSDYKLRWNPADFGNITSLRVPSEMIWIPDIVLYNNADGEFAVTHMTKAHLFSTGT 170
Query: 415 VSWIKRLDISTPISMQLDNWXNDMQTCTFKXGSRMHNSDEMD 540
V W+ + S+ + + D Q C K GS ++ ++D
Sbjct: 171 VHWVPPAIYKSSCSIDVTFFPFDQQNCKMKFGSWTYDKAKID 212
>M37981-1|AAA59942.1| 503|Homo sapiens neuronal nicotinic
acetylcholine receptor protein.
Length = 503
Score = 58.0 bits (134), Expect = 4e-08
Identities = 29/102 (28%), Positives = 53/102 (51%), Gaps = 2/102 (1%)
Frame = +1
Query: 241 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 414
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 85 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 144
Query: 415 VSWIKRLDISTPISMQLDNWXNDMQTCTFKXGSRMHNSDEMD 540
V+WI + + + + D Q CT K GS ++ ++D
Sbjct: 145 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKID 186
>BT006897-1|AAP35543.1| 505|Homo sapiens cholinergic receptor,
nicotinic, alpha polypeptide 3 protein.
Length = 505
Score = 58.0 bits (134), Expect = 4e-08
Identities = 29/102 (28%), Positives = 53/102 (51%), Gaps = 2/102 (1%)
Frame = +1
Query: 241 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 414
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 87 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 146
Query: 415 VSWIKRLDISTPISMQLDNWXNDMQTCTFKXGSRMHNSDEMD 540
V+WI + + + + D Q CT K GS ++ ++D
Sbjct: 147 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKID 188
>BT006646-1|AAP35292.1| 489|Homo sapiens cholinergic receptor,
nicotinic, alpha polypeptide 3 protein.
Length = 489
Score = 58.0 bits (134), Expect = 4e-08
Identities = 29/102 (28%), Positives = 53/102 (51%), Gaps = 2/102 (1%)
Frame = +1
Query: 241 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 414
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 87 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 146
Query: 415 VSWIKRLDISTPISMQLDNWXNDMQTCTFKXGSRMHNSDEMD 540
V+WI + + + + D Q CT K GS ++ ++D
Sbjct: 147 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKID 188
>BC098443-1|AAH98443.1| 504|Homo sapiens cholinergic receptor,
nicotinic, alpha 3 protein.
Length = 504
Score = 58.0 bits (134), Expect = 4e-08
Identities = 29/102 (28%), Positives = 53/102 (51%), Gaps = 2/102 (1%)
Frame = +1
Query: 241 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 414
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 86 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 145
Query: 415 VSWIKRLDISTPISMQLDNWXNDMQTCTFKXGSRMHNSDEMD 540
V+WI + + + + D Q CT K GS ++ ++D
Sbjct: 146 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKID 187
>BC023553-1|AAH23553.1| 501|Homo sapiens cholinergic receptor,
nicotinic, beta 1 (muscle) protein.
Length = 501
Score = 58.0 bits (134), Expect = 4e-08
Identities = 43/142 (30%), Positives = 70/142 (49%), Gaps = 6/142 (4%)
Frame = +1
Query: 139 RESPPDSKIVVNLTL-HLRHANIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLV 312
RE ++ V L L L N ++ E + ++ DL+ W D RLSW+ E G + +
Sbjct: 46 REVGDRVRVSVGLILAQLISLNEKDEEMSTKVYLDLE--WTDYRLSWDPAEHDGIDSLRI 103
Query: 313 SSERLWRPDVVLLNAAATTAGDY----ALRARVSNNGSVSWIKRLDISTPISMQLDNWXN 480
++E +W PDVVLLN G++ + VS++GSV W + S+Q+ +
Sbjct: 104 TAESVWLPDVVLLN---NNDGNFYVALDISVVVSSDGSVRWQPPGIYRSSCSIQVTYFPF 160
Query: 481 DMQTCTFKXGSRMHNSDEMDFR 546
D Q CT S ++S E+ +
Sbjct: 161 DWQNCTMVFSSYSYDSSEVSLQ 182
>BC006114-1|AAH06114.1| 489|Homo sapiens CHRNA3 protein protein.
Length = 489
Score = 58.0 bits (134), Expect = 4e-08
Identities = 29/102 (28%), Positives = 53/102 (51%), Gaps = 2/102 (1%)
Frame = +1
Query: 241 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 414
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 87 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 146
Query: 415 VSWIKRLDISTPISMQLDNWXNDMQTCTFKXGSRMHNSDEMD 540
V+WI + + + + D Q CT K GS ++ ++D
Sbjct: 147 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKID 188
>BC002996-1|AAH02996.1| 505|Homo sapiens cholinergic receptor,
nicotinic, alpha 3 protein.
Length = 505
Score = 58.0 bits (134), Expect = 4e-08
Identities = 29/102 (28%), Positives = 53/102 (51%), Gaps = 2/102 (1%)
Frame = +1
Query: 241 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 414
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 87 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 146
Query: 415 VSWIKRLDISTPISMQLDNWXNDMQTCTFKXGSRMHNSDEMD 540
V+WI + + + + D Q CT K GS ++ ++D
Sbjct: 147 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKID 188
>BC001642-1|AAH01642.1| 505|Homo sapiens cholinergic receptor,
nicotinic, alpha 3 protein.
Length = 505
Score = 58.0 bits (134), Expect = 4e-08
Identities = 29/102 (28%), Positives = 53/102 (51%), Gaps = 2/102 (1%)
Frame = +1
Query: 241 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 414
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 87 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 146
Query: 415 VSWIKRLDISTPISMQLDNWXNDMQTCTFKXGSRMHNSDEMD 540
V+WI + + + + D Q CT K GS ++ ++D
Sbjct: 147 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKID 188
>BC000513-1|AAH00513.1| 505|Homo sapiens cholinergic receptor,
nicotinic, alpha 3 protein.
Length = 505
Score = 58.0 bits (134), Expect = 4e-08
Identities = 29/102 (28%), Positives = 53/102 (51%), Gaps = 2/102 (1%)
Frame = +1
Query: 241 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 414
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 87 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 146
Query: 415 VSWIKRLDISTPISMQLDNWXNDMQTCTFKXGSRMHNSDEMD 540
V+WI + + + + D Q CT K GS ++ ++D
Sbjct: 147 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKID 188
>AJ007783-1|CAA07682.1| 504|Homo sapiens nicotinic acetylcholine
receptor alpha-3 subunit protein.
Length = 504
Score = 58.0 bits (134), Expect = 4e-08
Identities = 29/102 (28%), Positives = 53/102 (51%), Gaps = 2/102 (1%)
Frame = +1
Query: 241 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 414
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 86 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 145
Query: 415 VSWIKRLDISTPISMQLDNWXNDMQTCTFKXGSRMHNSDEMD 540
V+WI + + + + D Q CT K GS ++ ++D
Sbjct: 146 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKID 187
>AF385584-1|AAK68110.1| 489|Homo sapiens nicotinic cholinergic
receptor alpha 3 protein.
Length = 489
Score = 58.0 bits (134), Expect = 4e-08
Identities = 29/102 (28%), Positives = 53/102 (51%), Gaps = 2/102 (1%)
Frame = +1
Query: 241 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 414
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 81 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 140
Query: 415 VSWIKRLDISTPISMQLDNWXNDMQTCTFKXGSRMHNSDEMD 540
V+WI + + + + D Q CT K GS ++ ++D
Sbjct: 141 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKID 182
>Y16282-1|CAA76155.1| 494|Homo sapiens nicotinic acetylcholine
receptor alpha6 subunit precursor protein.
Length = 494
Score = 57.6 bits (133), Expect = 5e-08
Identities = 40/163 (24%), Positives = 74/163 (45%), Gaps = 10/163 (6%)
Frame = +1
Query: 82 CENATSLSLMIDSLLATYDRESPPDSKIVVNLTLHL-----RHANIRESESTVRILADLQ 246
C + + L + Y++ P + +T+H + AN+ E + L+
Sbjct: 28 CVGCATEERLFHKLFSHYNQFIRPVENVSDPVTVHFEVAITQLANVDEVNQIMETNLWLR 87
Query: 247 MNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNG 411
W D +L W+ E+ G T V ++++W+PD+VL N A GD+ + +A + NG
Sbjct: 88 HIWNDYKLRWDPMEYDGIETLRVPADKIWKPDIVLYNNAV---GDFQVEGKTKALLKYNG 144
Query: 412 SVSWIKRLDISTPISMQLDNWXNDMQTCTFKXGSRMHNSDEMD 540
++W + M + + D Q C+ K GS ++ E+D
Sbjct: 145 MITWTPPAIFKSSCPMDITFFPFDHQNCSLKFGSWTYDKAEID 187
>U62435-1|AAB40113.1| 494|Homo sapiens nicotinic acetylcholine
receptor alpha6 subunit precursor protein.
Length = 494
Score = 57.6 bits (133), Expect = 5e-08
Identities = 40/163 (24%), Positives = 74/163 (45%), Gaps = 10/163 (6%)
Frame = +1
Query: 82 CENATSLSLMIDSLLATYDRESPPDSKIVVNLTLHL-----RHANIRESESTVRILADLQ 246
C + + L + Y++ P + +T+H + AN+ E + L+
Sbjct: 28 CVGCATEERLFHKLFSHYNQFIRPVENVSDPVTVHFEVAITQLANVDEVNQIMETNLWLR 87
Query: 247 MNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNG 411
W D +L W+ E+ G T V ++++W+PD+VL N A GD+ + +A + NG
Sbjct: 88 HIWNDYKLRWDPMEYDGIETLRVPADKIWKPDIVLYNNAV---GDFQVEGKTKALLKYNG 144
Query: 412 SVSWIKRLDISTPISMQLDNWXNDMQTCTFKXGSRMHNSDEMD 540
++W + M + + D Q C+ K GS ++ E+D
Sbjct: 145 MITWTPPAIFKSSCPMDITFFPFDHQNCSLKFGSWTYDKAEID 187
>BC014456-1|AAH14456.1| 494|Homo sapiens cholinergic receptor,
nicotinic, alpha 6 protein.
Length = 494
Score = 57.6 bits (133), Expect = 5e-08
Identities = 40/163 (24%), Positives = 74/163 (45%), Gaps = 10/163 (6%)
Frame = +1
Query: 82 CENATSLSLMIDSLLATYDRESPPDSKIVVNLTLHL-----RHANIRESESTVRILADLQ 246
C + + L + Y++ P + +T+H + AN+ E + L+
Sbjct: 28 CVGCATEERLFHKLFSHYNQFIRPVENVSDPVTVHFEVAITQLANVDEVNQIMETNLWLR 87
Query: 247 MNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNG 411
W D +L W+ E+ G T V ++++W+PD+VL N A GD+ + +A + NG
Sbjct: 88 HIWNDYKLRWDPMEYDGIETLRVPADKIWKPDIVLYNNAV---GDFQVEGKTKALLKYNG 144
Query: 412 SVSWIKRLDISTPISMQLDNWXNDMQTCTFKXGSRMHNSDEMD 540
++W + M + + D Q C+ K GS ++ E+D
Sbjct: 145 MITWTPPAIFKSSCPMDITFFPFDHQNCSLKFGSWTYDKAEID 187
>AB079251-1|BAC06855.1| 494|Homo sapiens Nicotinic acetylcholine
receptor alpha 6 protein.
Length = 494
Score = 57.6 bits (133), Expect = 5e-08
Identities = 40/163 (24%), Positives = 74/163 (45%), Gaps = 10/163 (6%)
Frame = +1
Query: 82 CENATSLSLMIDSLLATYDRESPPDSKIVVNLTLHL-----RHANIRESESTVRILADLQ 246
C + + L + Y++ P + +T+H + AN+ E + L+
Sbjct: 28 CVGCATEERLFHKLFSHYNQFIRPVENVSDPVTVHFEVAITQLANVDEVNQIMETNLWLR 87
Query: 247 MNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNG 411
W D +L W+ E+ G T V ++++W+PD+VL N A GD+ + +A + NG
Sbjct: 88 HIWNDYKLRWDPMEYDGIETLRVPADKIWKPDIVLYNNAV---GDFQVEGKTKALLKYNG 144
Query: 412 SVSWIKRLDISTPISMQLDNWXNDMQTCTFKXGSRMHNSDEMD 540
++W + M + + D Q C+ K GS ++ E+D
Sbjct: 145 MITWTPPAIFKSSCPMDITFFPFDHQNCSLKFGSWTYDKAEID 187
>X66403-1|CAA47030.1| 493|Homo sapiens acetylcholine receptor
epsilon subunit CHRNE protein.
Length = 493
Score = 57.2 bits (132), Expect = 7e-08
Identities = 34/134 (25%), Positives = 69/134 (51%), Gaps = 3/134 (2%)
Frame = +1
Query: 151 PDSKIVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEWG-CSTWLVSSER 324
P+ + ++L + L + ++ E E T+ + ++W D RL+++ ++G T V SE
Sbjct: 45 PEDTVTISLKVTLTNLISLNEKEETLTTSVWIGIDWQDYRLNYSKDDFGGIETLRVPSEL 104
Query: 325 LWRPDVVLLNAAATTAG-DYALRARVSNNGSVSWIKRLDISTPISMQLDNWXNDMQTCTF 501
+W P++VL N G Y V GSV+W+ + ++++ + D Q C+
Sbjct: 105 VWLPEIVLENNIDGQFGVAYDANVLVYEGGSVTWLPPAIYRSVCAVEVTYFPFDWQNCSL 164
Query: 502 KXGSRMHNSDEMDF 543
S+ +N++E++F
Sbjct: 165 IFRSQTYNAEEVEF 178
>M83712-1|AAA58357.1| 468|Homo sapiens nicotinic receptor alpha 5
subunit protein.
Length = 468
Score = 57.2 bits (132), Expect = 7e-08
Identities = 35/150 (23%), Positives = 68/150 (45%), Gaps = 6/150 (4%)
Frame = +1
Query: 109 MIDSLLATYDRESPP----DSKIVVNLTLHLRH-ANIRESESTVRILADLQMNWIDKRLS 273
++ L Y+R P + KI + L + ++ E + L+ WID +L
Sbjct: 50 LLKDLFQDYERWVRPVEHLNDKIKIKFGLAISQLVDVDEKNQLMTTNVWLKQEWIDVKLR 109
Query: 274 WNAGEWG-CSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVSWIKRLDISTP 450
WN ++G V S+ W PD+VL + A + + + NG+V+W + +
Sbjct: 110 WNPDDYGGIKVIRVPSDSSWTPDIVLFDNADGRFEGTSTKTVIRYNGTVTWTPPANYKSS 169
Query: 451 ISMQLDNWXNDMQTCTFKXGSRMHNSDEMD 540
++ + + D+Q C+ K GS ++ ++D
Sbjct: 170 CTIDVTFFPFDLQNCSMKFGSWTYDGSQVD 199
>AF105999-1|AAD24503.1| 493|Homo sapiens acetylcholine receptor
epsilon subunit protein.
Length = 493
Score = 57.2 bits (132), Expect = 7e-08
Identities = 34/134 (25%), Positives = 69/134 (51%), Gaps = 3/134 (2%)
Frame = +1
Query: 151 PDSKIVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEWG-CSTWLVSSER 324
P+ + ++L + L + ++ E E T+ + ++W D RL+++ ++G T V SE
Sbjct: 45 PEDTVTISLKVTLTNLISLNEKEETLTTSVWIGIDWQDYRLNYSKDDFGGIETLRVPSEL 104
Query: 325 LWRPDVVLLNAAATTAG-DYALRARVSNNGSVSWIKRLDISTPISMQLDNWXNDMQTCTF 501
+W P++VL N G Y V GSV+W+ + ++++ + D Q C+
Sbjct: 105 VWLPEIVLENNIDGQFGVAYDANVLVYEGGSVTWLPPAIYRSVCAVEVTYFPFDWQNCSL 164
Query: 502 KXGSRMHNSDEMDF 543
S+ +N++E++F
Sbjct: 165 IFRSQTYNAEEVEF 178
>M86383-1|AAC84176.1| 502|Homo sapiens nicotinic acetylcholine
receptor alpha 3 subunit precursor protein.
Length = 502
Score = 55.6 bits (128), Expect = 2e-07
Identities = 30/105 (28%), Positives = 55/105 (52%), Gaps = 5/105 (4%)
Frame = +1
Query: 241 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYAL----RARVSN 405
L+ W D +L WN +G + ++ V ++++W+PD+VL N A GD+ + +A +
Sbjct: 84 LKQIWNDYKLKWNPSGYGGAEFMRVPAQKIWKPDIVLYNNAV---GDFQVTTKTKALLKY 140
Query: 406 NGSVSWIKRLDISTPISMQLDNWXNDMQTCTFKXGSRMHNSDEMD 540
G V+WI + + + + D Q CT K GS ++ ++D
Sbjct: 141 TGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKID 185
>Y08421-1|CAA69698.1| 627|Homo sapiens nicotinic acetylcholine
receptor alpha4 subunit precursor protein.
Length = 627
Score = 55.2 bits (127), Expect = 3e-07
Identities = 40/154 (25%), Positives = 77/154 (50%), Gaps = 10/154 (6%)
Frame = +1
Query: 109 MIDSLLATYDRESPPDSKI--VVNLTLHLRHANIRESESTVRILAD---LQMNWIDKRLS 273
++ L + Y++ S P + I VV + L A + + + +++ ++ W D +L
Sbjct: 40 LLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLR 99
Query: 274 WNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNGSVSWIKRLD 438
W+ ++ T + + SE +WRPD+VL N A GD+A+ +A + ++G V W
Sbjct: 100 WDPADYENVTSIRIPSELIWRPDIVLYNNAD---GDFAVTHLTKAHLFHDGRVQWTPPAI 156
Query: 439 ISTPISMQLDNWXNDMQTCTFKXGSRMHNSDEMD 540
+ S+ + + D Q CT K GS ++ ++D
Sbjct: 157 YKSSCSIDVTFFPFDQQNCTMKFGSWTYDKAKID 190
>X89741-1|CAA61893.1| 627|Homo sapiens neuronal acetylcholine
receptor alpha-4 subunit protein.
Length = 627
Score = 55.2 bits (127), Expect = 3e-07
Identities = 40/154 (25%), Positives = 77/154 (50%), Gaps = 10/154 (6%)
Frame = +1
Query: 109 MIDSLLATYDRESPPDSKI--VVNLTLHLRHANIRESESTVRILAD---LQMNWIDKRLS 273
++ L + Y++ S P + I VV + L A + + + +++ ++ W D +L
Sbjct: 40 LLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLR 99
Query: 274 WNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNGSVSWIKRLD 438
W+ ++ T + + SE +WRPD+VL N A GD+A+ +A + ++G V W
Sbjct: 100 WDPADYENVTSIRIPSELIWRPDIVLYNNAD---GDFAVTHLTKAHLFHDGRVQWTPPAI 156
Query: 439 ISTPISMQLDNWXNDMQTCTFKXGSRMHNSDEMD 540
+ S+ + + D Q CT K GS ++ ++D
Sbjct: 157 YKSSCSIDVTFFPFDQQNCTMKFGSWTYDKAKID 190
>X87629-1|CAA60959.1| 602|Homo sapiens nicotinic acetylcholine
receptor protein.
Length = 602
Score = 55.2 bits (127), Expect = 3e-07
Identities = 40/154 (25%), Positives = 77/154 (50%), Gaps = 10/154 (6%)
Frame = +1
Query: 109 MIDSLLATYDRESPPDSKI--VVNLTLHLRHANIRESESTVRILAD---LQMNWIDKRLS 273
++ L + Y++ S P + I VV + L A + + + +++ ++ W D +L
Sbjct: 15 LLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLR 74
Query: 274 WNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNGSVSWIKRLD 438
W+ ++ T + + SE +WRPD+VL N A GD+A+ +A + ++G V W
Sbjct: 75 WDPADYENVTSIRIPSELIWRPDIVLYNNAD---GDFAVTHLTKAHLFHDGRVQWTPPAI 131
Query: 439 ISTPISMQLDNWXNDMQTCTFKXGSRMHNSDEMD 540
+ S+ + + D Q CT K GS ++ ++D
Sbjct: 132 YKSSCSIDVTFFPFDQQNCTMKFGSWTYDKAKID 165
>U62433-1|AAB40111.1| 627|Homo sapiens nicotinic acetylcholine
receptor alpha4 subunit precursor protein.
Length = 627
Score = 55.2 bits (127), Expect = 3e-07
Identities = 40/154 (25%), Positives = 77/154 (50%), Gaps = 10/154 (6%)
Frame = +1
Query: 109 MIDSLLATYDRESPPDSKI--VVNLTLHLRHANIRESESTVRILAD---LQMNWIDKRLS 273
++ L + Y++ S P + I VV + L A + + + +++ ++ W D +L
Sbjct: 40 LLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLR 99
Query: 274 WNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNGSVSWIKRLD 438
W+ ++ T + + SE +WRPD+VL N A GD+A+ +A + ++G V W
Sbjct: 100 WDPADYENVTSIRIPSELIWRPDIVLYNNAD---GDFAVTHLTKAHLFHDGRVQWTPPAI 156
Query: 439 ISTPISMQLDNWXNDMQTCTFKXGSRMHNSDEMD 540
+ S+ + + D Q CT K GS ++ ++D
Sbjct: 157 YKSSCSIDVTFFPFDQQNCTMKFGSWTYDKAKID 190
>L35901-1|AAA64743.1| 627|Homo sapiens nicotinic acetylcholine
receptor alpha 4 subunit protein.
Length = 627
Score = 55.2 bits (127), Expect = 3e-07
Identities = 40/154 (25%), Positives = 77/154 (50%), Gaps = 10/154 (6%)
Frame = +1
Query: 109 MIDSLLATYDRESPPDSKI--VVNLTLHLRHANIRESESTVRILAD---LQMNWIDKRLS 273
++ L + Y++ S P + I VV + L A + + + +++ ++ W D +L
Sbjct: 40 LLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLR 99
Query: 274 WNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNGSVSWIKRLD 438
W+ ++ T + + SE +WRPD+VL N A GD+A+ +A + ++G V W
Sbjct: 100 WDPADYENVTSIRIPSELIWRPDIVLYNNAD---GDFAVTHLTKAHLFHDGRVQWTPPAI 156
Query: 439 ISTPISMQLDNWXNDMQTCTFKXGSRMHNSDEMD 540
+ S+ + + D Q CT K GS ++ ++D
Sbjct: 157 YKSSCSIDVTFFPFDQQNCTMKFGSWTYDKAKID 190
>DQ093071-1|AAY88737.1| 627|Homo sapiens cholinergic receptor,
nicotinic, alpha polypeptide 4 protein.
Length = 627
Score = 55.2 bits (127), Expect = 3e-07
Identities = 40/154 (25%), Positives = 77/154 (50%), Gaps = 10/154 (6%)
Frame = +1
Query: 109 MIDSLLATYDRESPPDSKI--VVNLTLHLRHANIRESESTVRILAD---LQMNWIDKRLS 273
++ L + Y++ S P + I VV + L A + + + +++ ++ W D +L
Sbjct: 40 LLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLR 99
Query: 274 WNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNGSVSWIKRLD 438
W+ ++ T + + SE +WRPD+VL N A GD+A+ +A + ++G V W
Sbjct: 100 WDPADYENVTSIRIPSELIWRPDIVLYNNAD---GDFAVTHLTKAHLFHDGRVQWTPPAI 156
Query: 439 ISTPISMQLDNWXNDMQTCTFKXGSRMHNSDEMD 540
+ S+ + + D Q CT K GS ++ ++D
Sbjct: 157 YKSSCSIDVTFFPFDQQNCTMKFGSWTYDKAKID 190
>BC096290-1|AAH96290.1| 627|Homo sapiens cholinergic receptor,
nicotinic, alpha 4 protein.
Length = 627
Score = 55.2 bits (127), Expect = 3e-07
Identities = 40/154 (25%), Positives = 77/154 (50%), Gaps = 10/154 (6%)
Frame = +1
Query: 109 MIDSLLATYDRESPPDSKI--VVNLTLHLRHANIRESESTVRILAD---LQMNWIDKRLS 273
++ L + Y++ S P + I VV + L A + + + +++ ++ W D +L
Sbjct: 40 LLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLR 99
Query: 274 WNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNGSVSWIKRLD 438
W+ ++ T + + SE +WRPD+VL N A GD+A+ +A + ++G V W
Sbjct: 100 WDPADYENVTSIRIPSELIWRPDIVLYNNAD---GDFAVTHLTKAHLFHDGRVQWTPPAI 156
Query: 439 ISTPISMQLDNWXNDMQTCTFKXGSRMHNSDEMD 540
+ S+ + + D Q CT K GS ++ ++D
Sbjct: 157 YKSSCSIDVTFFPFDQQNCTMKFGSWTYDKAKID 190
>X01715-1|CAA25861.1| 520|Homo sapiens acetylcholine receptor gamma
chain precursor protein.
Length = 520
Score = 54.8 bits (126), Expect = 4e-07
Identities = 41/154 (26%), Positives = 72/154 (46%), Gaps = 8/154 (5%)
Frame = +1
Query: 109 MIDSLLATYDRESPPDSKI--VVNLTLHLRHANI---RESESTVRILADLQMNWIDKRLS 273
++ L+ YD P + VVN++L L N+ E E + ++M W D RL
Sbjct: 32 LLADLMQNYDPNLRPAERDSDVVNVSLKLTLTNLISLNEREEALTTNVWIEMQWCDYRLR 91
Query: 274 WNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARV--SNNGSVSWIKRLDIS 444
W+ ++ G V S +WRPD+VL N + AL V S +G + W+
Sbjct: 92 WDPRDYEGLWVLRVPSTMVWRPDIVLENNVDGVF-EVALYCNVLVSPDGCIYWLPPAIFR 150
Query: 445 TPISMQLDNWXNDMQTCTFKXGSRMHNSDEMDFR 546
+ S+ + + D Q C+ S+ ++++E+D +
Sbjct: 151 SACSISVTYFPFDWQNCSLIFQSQTYSTNEIDLQ 184
>AC092165-3|AAY24103.1| 520|Homo sapiens unknown protein.
Length = 520
Score = 54.8 bits (126), Expect = 4e-07
Identities = 41/154 (26%), Positives = 72/154 (46%), Gaps = 8/154 (5%)
Frame = +1
Query: 109 MIDSLLATYDRESPPDSKI--VVNLTLHLRHANI---RESESTVRILADLQMNWIDKRLS 273
++ L+ YD P + VVN++L L N+ E E + ++M W D RL
Sbjct: 32 LLADLMQNYDPNLRPAERDSDVVNVSLKLTLTNLISLNEREEALTTNVWIEMQWCDYRLR 91
Query: 274 WNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARV--SNNGSVSWIKRLDIS 444
W+ ++ G V S +WRPD+VL N + AL V S +G + W+
Sbjct: 92 WDPRDYEGLWVLRVPSTMVWRPDIVLENNVDGVF-EVALYCNVLVSPDGCIYWLPPAIFR 150
Query: 445 TPISMQLDNWXNDMQTCTFKXGSRMHNSDEMDFR 546
+ S+ + + D Q C+ S+ ++++E+D +
Sbjct: 151 SACSISVTYFPFDWQNCSLIFQSQTYSTNEIDLQ 184
>Y00762-1|CAA68731.1| 457|Homo sapiens protein ( Human mRNA for
muscle acetylcholine receptor alpha-subunit. ).
Length = 457
Score = 54.0 bits (124), Expect = 6e-07
Identities = 33/123 (26%), Positives = 60/123 (48%), Gaps = 5/123 (4%)
Frame = +1
Query: 160 KIVVNLTLHLRHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRP 336
++ V L L ++ N+ E V L+ W+D L WN ++G + + SE++WRP
Sbjct: 50 EVTVGLQL-IQLINVDEVNQIVTTNVRLKQQWVDYNLKWNPDDYGGVKKIHIPSEKIWRP 108
Query: 337 DVVLLNAAATTAGDYAL----RARVSNNGSVSWIKRLDISTPISMQLDNWXNDMQTCTFK 504
D+VL N A GD+A+ + + G ++W + + + ++ D Q C+ K
Sbjct: 109 DLVLYNNA---DGDFAIVKFTKVLLQYTGHITWTPPAIFKSYCEIIVTHFPFDEQNCSMK 165
Query: 505 XGS 513
G+
Sbjct: 166 LGT 168
>X02502-1|CAA26344.1| 457|Homo sapiens acetylcholine receptor
protein.
Length = 457
Score = 54.0 bits (124), Expect = 6e-07
Identities = 33/123 (26%), Positives = 60/123 (48%), Gaps = 5/123 (4%)
Frame = +1
Query: 160 KIVVNLTLHLRHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRP 336
++ V L L ++ N+ E V L+ W+D L WN ++G + + SE++WRP
Sbjct: 50 EVTVGLQL-IQLINVDEVNQIVTTNVRLKQQWVDYNLKWNPDDYGGVKKIHIPSEKIWRP 108
Query: 337 DVVLLNAAATTAGDYAL----RARVSNNGSVSWIKRLDISTPISMQLDNWXNDMQTCTFK 504
D+VL N A GD+A+ + + G ++W + + + ++ D Q C+ K
Sbjct: 109 DLVLYNNA---DGDFAIVKFTKVLLQYTGHITWTPPAIFKSYCEIIVTHFPFDEQNCSMK 165
Query: 505 XGS 513
G+
Sbjct: 166 LGT 168
>S77094-1|AAD14247.1| 457|Homo sapiens nicotinic acetylcholine
receptor alpha subunit|AChR protein.
Length = 457
Score = 54.0 bits (124), Expect = 6e-07
Identities = 33/123 (26%), Positives = 60/123 (48%), Gaps = 5/123 (4%)
Frame = +1
Query: 160 KIVVNLTLHLRHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRP 336
++ V L L ++ N+ E V L+ W+D L WN ++G + + SE++WRP
Sbjct: 50 EVTVGLQL-IQLINVDEVNQIVTTNVRLKQQWVDYNLKWNPDDYGGVKKIHIPSEKIWRP 108
Query: 337 DVVLLNAAATTAGDYAL----RARVSNNGSVSWIKRLDISTPISMQLDNWXNDMQTCTFK 504
D+VL N A GD+A+ + + G ++W + + + ++ D Q C+ K
Sbjct: 109 DLVLYNNA---DGDFAIVKFTKVLLQYTGHITWTPPAIFKSYCEIIVTHFPFDEQNCSMK 165
Query: 505 XGS 513
G+
Sbjct: 166 LGT 168
>BC006314-1|AAH06314.1| 269|Homo sapiens CHRNA1 protein protein.
Length = 269
Score = 54.0 bits (124), Expect = 6e-07
Identities = 33/123 (26%), Positives = 60/123 (48%), Gaps = 5/123 (4%)
Frame = +1
Query: 160 KIVVNLTLHLRHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRP 336
++ V L L ++ N+ E V L+ W+D L WN ++G + + SE++WRP
Sbjct: 50 EVTVGLQL-IQLINVDEVNQIVTTNVRLKQQWVDYNLKWNPDDYGGVKKIHIPSEKIWRP 108
Query: 337 DVVLLNAAATTAGDYAL----RARVSNNGSVSWIKRLDISTPISMQLDNWXNDMQTCTFK 504
D+VL N A GD+A+ + + G ++W + + + ++ D Q C+ K
Sbjct: 109 DLVLYNNA---DGDFAIVKFTKVLLQYTGHITWTPPAIFKSYCEIIVTHFPFDEQNCSMK 165
Query: 505 XGS 513
G+
Sbjct: 166 LGT 168
>AJ295237-1|CAC16144.1| 450|Homo sapiens neuronal nicotinic
acetylcholine receptor subunit4 protein.
Length = 450
Score = 54.0 bits (124), Expect = 6e-07
Identities = 44/167 (26%), Positives = 72/167 (43%), Gaps = 10/167 (5%)
Frame = +1
Query: 76 AEC---ENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHANIRESESTVRILAD 240
AEC E +L L D L A Y P D+ +N+TL + + I + + ++L
Sbjct: 20 AECLGAEGRLALKLFRD-LFANYTSALRPVADTDQTLNVTLEVTLSQIIDMDERNQVLTL 78
Query: 241 ---LQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSN 405
++ W D L W+ +G + S +WRPD+VL N A A G + + +
Sbjct: 79 YLWIRQEWTDAYLRWDPNAYGGLDAIRIPSSLVWRPDIVLYNKADAQPPGSASTNVVLRH 138
Query: 406 NGSVSWIKRLDISTPISMQLDNWXNDMQTCTFKXGSRMHNSDEMDFR 546
+G+V W + + + + D Q C GS H ++D R
Sbjct: 139 DGAVRWDAPAITRSSCRVDVAAFPFDAQHCGLTFGSWTHGGHQLDVR 185
>AJ278118-1|CAC20435.1| 450|Homo sapiens neuronal nicotinic
acetylcholine alpha10 subunit protein.
Length = 450
Score = 54.0 bits (124), Expect = 6e-07
Identities = 44/167 (26%), Positives = 72/167 (43%), Gaps = 10/167 (5%)
Frame = +1
Query: 76 AEC---ENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHANIRESESTVRILAD 240
AEC E +L L D L A Y P D+ +N+TL + + I + + ++L
Sbjct: 20 AECLGAEGRLALKLFRD-LFANYTSALRPVADTDQTLNVTLEVTLSQIIDMDERNQVLTL 78
Query: 241 ---LQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSN 405
++ W D L W+ +G + S +WRPD+VL N A A G + + +
Sbjct: 79 YLWIRQEWTDAYLRWDPNAYGGLDAIRIPSSLVWRPDIVLYNKADAQPPGSASTNVVLRH 138
Query: 406 NGSVSWIKRLDISTPISMQLDNWXNDMQTCTFKXGSRMHNSDEMDFR 546
+G+V W + + + + D Q C GS H ++D R
Sbjct: 139 DGAVRWDAPAITRSSCRVDVAAFPFDAQHCGLTFGSWTHGGHQLDVR 185
>AF327367-1|AAK14333.1| 450|Homo sapiens nicotinic acetylcholine
receptor subunit alpha 10 protein.
Length = 450
Score = 54.0 bits (124), Expect = 6e-07
Identities = 44/167 (26%), Positives = 72/167 (43%), Gaps = 10/167 (5%)
Frame = +1
Query: 76 AEC---ENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHANIRESESTVRILAD 240
AEC E +L L D L A Y P D+ +N+TL + + I + + ++L
Sbjct: 20 AECLGAEGRLALKLFRD-LFANYTSALRPVADTDQTLNVTLEVTLSQIIDMDERNQVLTL 78
Query: 241 ---LQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSN 405
++ W D L W+ +G + S +WRPD+VL N A A G + + +
Sbjct: 79 YLWIRQEWTDAYLRWDPNAYGGLDAIRIPSSLVWRPDIVLYNKADAQPPGSASTNVVLRH 138
Query: 406 NGSVSWIKRLDISTPISMQLDNWXNDMQTCTFKXGSRMHNSDEMDFR 546
+G+V W + + + + D Q C GS H ++D R
Sbjct: 139 DGAVRWDAPAITRSSCRVDVAAFPFDAQHCGLTFGSWTHGGHQLDVR 185
>AF199235-1|AAG00795.2| 450|Homo sapiens nicotinic acetylcholine
receptor subunit alpha 10 protein.
Length = 450
Score = 54.0 bits (124), Expect = 6e-07
Identities = 44/167 (26%), Positives = 72/167 (43%), Gaps = 10/167 (5%)
Frame = +1
Query: 76 AEC---ENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHANIRESESTVRILAD 240
AEC E +L L D L A Y P D+ +N+TL + + I + + ++L
Sbjct: 20 AECLGAEGRLALKLFRD-LFANYTSALRPVADTDQTLNVTLEVTLSQIIDMDERNQVLTL 78
Query: 241 ---LQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSN 405
++ W D L W+ +G + S +WRPD+VL N A A G + + +
Sbjct: 79 YLWIRQEWTDAYLRWDPNAYGGLDAIRIPSSLVWRPDIVLYNKADAQPPGSASTNVVLRH 138
Query: 406 NGSVSWIKRLDISTPISMQLDNWXNDMQTCTFKXGSRMHNSDEMDFR 546
+G+V W + + + + D Q C GS H ++D R
Sbjct: 139 DGAVRWDAPAITRSSCRVDVAAFPFDAQHCGLTFGSWTHGGHQLDVR 185
>AC018890-1|AAY14687.1| 457|Homo sapiens unknown protein.
Length = 457
Score = 54.0 bits (124), Expect = 6e-07
Identities = 33/123 (26%), Positives = 60/123 (48%), Gaps = 5/123 (4%)
Frame = +1
Query: 160 KIVVNLTLHLRHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRP 336
++ V L L ++ N+ E V L+ W+D L WN ++G + + SE++WRP
Sbjct: 50 EVTVGLQL-IQLINVDEVNQIVTTNVRLKQQWVDYNLKWNPDDYGGVKKIHIPSEKIWRP 108
Query: 337 DVVLLNAAATTAGDYAL----RARVSNNGSVSWIKRLDISTPISMQLDNWXNDMQTCTFK 504
D+VL N A GD+A+ + + G ++W + + + ++ D Q C+ K
Sbjct: 109 DLVLYNNA---DGDFAIVKFTKVLLQYTGHITWTPPAIFKSYCEIIVTHFPFDEQNCSMK 165
Query: 505 XGS 513
G+
Sbjct: 166 LGT 168
>BC113575-1|AAI13576.1| 479|Homo sapiens cholinergic receptor,
nicotinic, alpha 9 protein.
Length = 479
Score = 53.2 bits (122), Expect = 1e-06
Identities = 37/163 (22%), Positives = 74/163 (45%), Gaps = 7/163 (4%)
Frame = +1
Query: 73 AAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHANIRESESTVRILAD-- 240
AAE + + + L Y P D+ V+N+TL + + I++ + +IL
Sbjct: 22 AAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQITLSQIKDMDERNQILTAYL 81
Query: 241 -LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGD-YALRARVSNNG 411
++ W D L+W+ ++ G + + S+ +WRPD+VL N A + + + +G
Sbjct: 82 WIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKADDESSEPVNTNVVLRYDG 141
Query: 412 SVSWIKRLDISTPISMQLDNWXNDMQTCTFKXGSRMHNSDEMD 540
++W + + + + D Q C GS +N +++D
Sbjct: 142 LITWDAPAITKSSCVVDVTYFPFDNQQCNLTFGSWTYNGNQVD 184
>BC113549-1|AAI13550.1| 479|Homo sapiens cholinergic receptor,
nicotinic, alpha 9 protein.
Length = 479
Score = 53.2 bits (122), Expect = 1e-06
Identities = 37/163 (22%), Positives = 74/163 (45%), Gaps = 7/163 (4%)
Frame = +1
Query: 73 AAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHANIRESESTVRILAD-- 240
AAE + + + L Y P D+ V+N+TL + + I++ + +IL
Sbjct: 22 AAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQITLSQIKDMDERNQILTAYL 81
Query: 241 -LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGD-YALRARVSNNG 411
++ W D L+W+ ++ G + + S+ +WRPD+VL N A + + + +G
Sbjct: 82 WIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKADDESSEPVNTNVVLRYDG 141
Query: 412 SVSWIKRLDISTPISMQLDNWXNDMQTCTFKXGSRMHNSDEMD 540
++W + + + + D Q C GS +N +++D
Sbjct: 142 LITWDAPAITKSSCVVDVTYFPFDNQQCNLTFGSWTYNGNQVD 184
>AY123244-1|AAM74523.1| 479|Homo sapiens nicotinic acetylcholine
receptor subunit alpha 9 protein.
Length = 479
Score = 53.2 bits (122), Expect = 1e-06
Identities = 37/163 (22%), Positives = 74/163 (45%), Gaps = 7/163 (4%)
Frame = +1
Query: 73 AAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHANIRESESTVRILAD-- 240
AAE + + + L Y P D+ V+N+TL + + I++ + +IL
Sbjct: 22 AAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQITLSQIKDMDERNQILTAYL 81
Query: 241 -LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGD-YALRARVSNNG 411
++ W D L+W+ ++ G + + S+ +WRPD+VL N A + + + +G
Sbjct: 82 WIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKADDESSEPVNTNVVLRYDG 141
Query: 412 SVSWIKRLDISTPISMQLDNWXNDMQTCTFKXGSRMHNSDEMD 540
++W + + + + D Q C GS +N +++D
Sbjct: 142 LITWDAPAITKSSCVVDVTYFPFDNQQCNLTFGSWTYNGNQVD 184
>AJ243342-1|CAB65091.1| 479|Homo sapiens nicotinic acetylcholine
receptor alpha 9 subunit protein.
Length = 479
Score = 53.2 bits (122), Expect = 1e-06
Identities = 37/163 (22%), Positives = 74/163 (45%), Gaps = 7/163 (4%)
Frame = +1
Query: 73 AAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHANIRESESTVRILAD-- 240
AAE + + + L Y P D+ V+N+TL + + I++ + +IL
Sbjct: 22 AAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQITLSQIKDMDERNQILTAYL 81
Query: 241 -LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGD-YALRARVSNNG 411
++ W D L+W+ ++ G + + S+ +WRPD+VL N A + + + +G
Sbjct: 82 WIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKADDESSEPVNTNVVLRYDG 141
Query: 412 SVSWIKRLDISTPISMQLDNWXNDMQTCTFKXGSRMHNSDEMD 540
++W + + + + D Q C GS +N +++D
Sbjct: 142 LITWDAPAITKSSCVVDVTYFPFDNQQCNLTFGSWTYNGNQVD 184
>AF227732-1|AAF61920.1| 470|Homo sapiens nicotinic acetylcholine
receptor alpha 9 subunit protein.
Length = 470
Score = 53.2 bits (122), Expect = 1e-06
Identities = 37/163 (22%), Positives = 74/163 (45%), Gaps = 7/163 (4%)
Frame = +1
Query: 73 AAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHANIRESESTVRILAD-- 240
AAE + + + L Y P D+ V+N+TL + + I++ + +IL
Sbjct: 16 AAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQITLSQIKDMDERNQILTAYL 75
Query: 241 -LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGD-YALRARVSNNG 411
++ W D L+W+ ++ G + + S+ +WRPD+VL N A + + + +G
Sbjct: 76 WIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKADDESSEPVNTNVVLRYDG 135
Query: 412 SVSWIKRLDISTPISMQLDNWXNDMQTCTFKXGSRMHNSDEMD 540
++W + + + + D Q C GS +N +++D
Sbjct: 136 LITWDAPAITKSSCVVDVTYFPFDNQQCNLTFGSWTYNGNQVD 178
>AC118275-1|AAY40986.1| 479|Homo sapiens unknown protein.
Length = 479
Score = 53.2 bits (122), Expect = 1e-06
Identities = 37/163 (22%), Positives = 74/163 (45%), Gaps = 7/163 (4%)
Frame = +1
Query: 73 AAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHANIRESESTVRILAD-- 240
AAE + + + L Y P D+ V+N+TL + + I++ + +IL
Sbjct: 22 AAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQITLSQIKDMDERNQILTAYL 81
Query: 241 -LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGD-YALRARVSNNG 411
++ W D L+W+ ++ G + + S+ +WRPD+VL N A + + + +G
Sbjct: 82 WIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKADDESSEPVNTNVVLRYDG 141
Query: 412 SVSWIKRLDISTPISMQLDNWXNDMQTCTFKXGSRMHNSDEMD 540
++W + + + + D Q C GS +N +++D
Sbjct: 142 LITWDAPAITKSSCVVDVTYFPFDNQQCNLTFGSWTYNGNQVD 184
>Y08415-1|CAA69692.1| 502|Homo sapiens nicotinic acetylcholine
receptor beta2 subunit precursor protein.
Length = 502
Score = 52.0 bits (119), Expect = 3e-06
Identities = 35/129 (27%), Positives = 58/129 (44%), Gaps = 3/129 (2%)
Frame = +1
Query: 163 IVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 336
+ V L + L ++ E E + L W D RL+W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 337 DVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWXNDMQTCTFKXGS 513
DVVL N A + A VS +GS+ W+ + +++ ++ D Q CT K S
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRS 175
Query: 514 RMHNSDEMD 540
++ E+D
Sbjct: 176 WTYDRTEID 184
>X53179-1|CAA37320.1| 502|Homo sapiens precursor peptide (AA -25 to
477) protein.
Length = 502
Score = 52.0 bits (119), Expect = 3e-06
Identities = 35/129 (27%), Positives = 58/129 (44%), Gaps = 3/129 (2%)
Frame = +1
Query: 163 IVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 336
+ V L + L ++ E E + L W D RL+W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 337 DVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWXNDMQTCTFKXGS 513
DVVL N A + A VS +GS+ W+ + +++ ++ D Q CT K S
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRS 175
Query: 514 RMHNSDEMD 540
++ E+D
Sbjct: 176 WTYDRTEID 184
>U62437-1|AAB40115.1| 502|Homo sapiens nicotinic acetylcholine
receptor beta2 subunit precursor protein.
Length = 502
Score = 52.0 bits (119), Expect = 3e-06
Identities = 35/129 (27%), Positives = 58/129 (44%), Gaps = 3/129 (2%)
Frame = +1
Query: 163 IVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 336
+ V L + L ++ E E + L W D RL+W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 337 DVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWXNDMQTCTFKXGS 513
DVVL N A + A VS +GS+ W+ + +++ ++ D Q CT K S
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRS 175
Query: 514 RMHNSDEMD 540
++ E+D
Sbjct: 176 WTYDRTEID 184
>BC075041-1|AAH75041.1| 502|Homo sapiens cholinergic receptor,
nicotinic, beta 2 (neuronal) protein.
Length = 502
Score = 52.0 bits (119), Expect = 3e-06
Identities = 35/129 (27%), Positives = 58/129 (44%), Gaps = 3/129 (2%)
Frame = +1
Query: 163 IVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 336
+ V L + L ++ E E + L W D RL+W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 337 DVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWXNDMQTCTFKXGS 513
DVVL N A + A VS +GS+ W+ + +++ ++ D Q CT K S
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRS 175
Query: 514 RMHNSDEMD 540
++ E+D
Sbjct: 176 WTYDRTEID 184
>BC075040-1|AAH75040.1| 502|Homo sapiens cholinergic receptor,
nicotinic, beta 2 (neuronal) protein.
Length = 502
Score = 52.0 bits (119), Expect = 3e-06
Identities = 35/129 (27%), Positives = 58/129 (44%), Gaps = 3/129 (2%)
Frame = +1
Query: 163 IVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 336
+ V L + L ++ E E + L W D RL+W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 337 DVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWXNDMQTCTFKXGS 513
DVVL N A + A VS +GS+ W+ + +++ ++ D Q CT K S
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRS 175
Query: 514 RMHNSDEMD 540
++ E+D
Sbjct: 176 WTYDRTEID 184
>AL592078-3|CAI16184.1| 502|Homo sapiens cholinergic receptor,
nicotinic, beta 2 (neuronal) protein.
Length = 502
Score = 52.0 bits (119), Expect = 3e-06
Identities = 35/129 (27%), Positives = 58/129 (44%), Gaps = 3/129 (2%)
Frame = +1
Query: 163 IVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 336
+ V L + L ++ E E + L W D RL+W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 337 DVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWXNDMQTCTFKXGS 513
DVVL N A + A VS +GS+ W+ + +++ ++ D Q CT K S
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRS 175
Query: 514 RMHNSDEMD 540
++ E+D
Sbjct: 176 WTYDRTEID 184
>AJ001935-1|CAA05108.1| 504|Homo sapiens CHRNB2 protein.
Length = 504
Score = 52.0 bits (119), Expect = 3e-06
Identities = 35/129 (27%), Positives = 58/129 (44%), Gaps = 3/129 (2%)
Frame = +1
Query: 163 IVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 336
+ V L + L ++ E E + L W D RL+W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 337 DVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWXNDMQTCTFKXGS 513
DVVL N A + A VS +GS+ W+ + +++ ++ D Q CT K S
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRS 175
Query: 514 RMHNSDEMD 540
++ E+D
Sbjct: 176 WTYDRTEID 184
>AF077186-1|AAD45422.1| 502|Homo sapiens neuronal nicotinic
acetylcholine receptor beta 2 protein.
Length = 502
Score = 52.0 bits (119), Expect = 3e-06
Identities = 35/129 (27%), Positives = 58/129 (44%), Gaps = 3/129 (2%)
Frame = +1
Query: 163 IVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 336
+ V L + L ++ E E + L W D RL+W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 337 DVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWXNDMQTCTFKXGS 513
DVVL N A + A VS +GS+ W+ + +++ ++ D Q CT K S
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRS 175
Query: 514 RMHNSDEMD 540
++ E+D
Sbjct: 176 WTYDRTEID 184
>X55019-1|CAA38759.1| 517|Homo sapiens acetylcholine receptor delta
subunit protein.
Length = 517
Score = 50.4 bits (115), Expect = 8e-06
Identities = 36/142 (25%), Positives = 65/142 (45%), Gaps = 7/142 (4%)
Frame = +1
Query: 133 YDRESPP----DSKIVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEWG- 294
Y++E P + + V L L L + +++E E T+ ++ W D RL WNA E+G
Sbjct: 38 YNKELRPVAHKEESVDVALALTLSNLISLKEVEETLTTNVWIEHGWTDNRLKWNAEEFGN 97
Query: 295 CSTWLVSSERLWRPDVVL-LNAAATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDN 471
S + + +W P++VL N + Y+ V + G V W+ + + +
Sbjct: 98 ISVLRLPPDMVWLPEIVLENNNDGSFQISYSCNVLVYHYGFVYWLPPAIFRSSCPISVTY 157
Query: 472 WXNDMQTCTFKXGSRMHNSDEM 537
+ D Q C+ K S + + E+
Sbjct: 158 FPFDWQNCSLKFSSLKYTAKEI 179
>DQ644022-1|ABG35128.1| 456|Homo sapiens 5-HT3 receptor subunit E
splice variant HTR3Ea protein.
Length = 456
Score = 50.4 bits (115), Expect = 8e-06
Identities = 26/100 (26%), Positives = 48/100 (48%), Gaps = 1/100 (1%)
Frame = +1
Query: 241 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 417
L+M W + +SWN E G + ++++ LW PD+ ++ L A VSN G +
Sbjct: 91 LEMVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEGRI 150
Query: 418 SWIKRLDISTPISMQLDNWXNDMQTCTFKXGSRMHNSDEM 537
+ K + + + ++ + + D Q CT S ++ D M
Sbjct: 151 RYKKPMKVDSICNLDIFYFPFDQQNCTLTFSSFLYTVDSM 190
>BC101185-1|AAI01186.1| 374|Homo sapiens HTR3E protein protein.
Length = 374
Score = 50.4 bits (115), Expect = 8e-06
Identities = 26/100 (26%), Positives = 48/100 (48%), Gaps = 1/100 (1%)
Frame = +1
Query: 241 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 417
L+M W + +SWN E G + ++++ LW PD+ ++ L A VSN G +
Sbjct: 20 LEMVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEGRI 79
Query: 418 SWIKRLDISTPISMQLDNWXNDMQTCTFKXGSRMHNSDEM 537
+ K + + + ++ + + D Q CT S ++ D M
Sbjct: 80 RYKKPMKVDSICNLDIFYFPFDQQNCTLTFSSFLYTVDSM 119
>BC101183-1|AAI01184.1| 471|Homo sapiens 5-hydroxytryptamine
(serotonin) receptor 3, family member E protein.
Length = 471
Score = 50.4 bits (115), Expect = 8e-06
Identities = 26/100 (26%), Positives = 48/100 (48%), Gaps = 1/100 (1%)
Frame = +1
Query: 241 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 417
L+M W + +SWN E G + ++++ LW PD+ ++ L A VSN G +
Sbjct: 106 LEMVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEGRI 165
Query: 418 SWIKRLDISTPISMQLDNWXNDMQTCTFKXGSRMHNSDEM 537
+ K + + + ++ + + D Q CT S ++ D M
Sbjct: 166 RYKKPMKVDSICNLDIFYFPFDQQNCTLTFSSFLYTVDSM 205
>BC101182-1|AAI01183.1| 471|Homo sapiens 5-hydroxytryptamine
(serotonin) receptor 3, family member E protein.
Length = 471
Score = 50.4 bits (115), Expect = 8e-06
Identities = 26/100 (26%), Positives = 48/100 (48%), Gaps = 1/100 (1%)
Frame = +1
Query: 241 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 417
L+M W + +SWN E G + ++++ LW PD+ ++ L A VSN G +
Sbjct: 106 LEMVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEGRI 165
Query: 418 SWIKRLDISTPISMQLDNWXNDMQTCTFKXGSRMHNSDEM 537
+ K + + + ++ + + D Q CT S ++ D M
Sbjct: 166 RYKKPMKVDSICNLDIFYFPFDQQNCTLTFSSFLYTVDSM 205
>BC093925-1|AAH93925.1| 517|Homo sapiens cholinergic receptor,
nicotinic, delta protein.
Length = 517
Score = 50.4 bits (115), Expect = 8e-06
Identities = 36/142 (25%), Positives = 65/142 (45%), Gaps = 7/142 (4%)
Frame = +1
Query: 133 YDRESPP----DSKIVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEWG- 294
Y++E P + + V L L L + +++E E T+ ++ W D RL WNA E+G
Sbjct: 38 YNKELRPVAHKEESVDVALALTLSNLISLKEVEETLTTNVWIEHGWTDNRLKWNAEEFGN 97
Query: 295 CSTWLVSSERLWRPDVVL-LNAAATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDN 471
S + + +W P++VL N + Y+ V + G V W+ + + +
Sbjct: 98 ISVLRLPPDMVWLPEIVLENNNDGSFQISYSCNVLVYHYGFVYWLPPAIFRSSCPISVTY 157
Query: 472 WXNDMQTCTFKXGSRMHNSDEM 537
+ D Q C+ K S + + E+
Sbjct: 158 FPFDWQNCSLKFSSLKYTAKEI 179
>BC093923-1|AAH93923.1| 517|Homo sapiens cholinergic receptor,
nicotinic, delta protein.
Length = 517
Score = 50.4 bits (115), Expect = 8e-06
Identities = 36/142 (25%), Positives = 65/142 (45%), Gaps = 7/142 (4%)
Frame = +1
Query: 133 YDRESPP----DSKIVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEWG- 294
Y++E P + + V L L L + +++E E T+ ++ W D RL WNA E+G
Sbjct: 38 YNKELRPVAHKEESVDVALALTLSNLISLKEVEETLTTNVWIEHGWTDNRLKWNAEEFGN 97
Query: 295 CSTWLVSSERLWRPDVVL-LNAAATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDN 471
S + + +W P++VL N + Y+ V + G V W+ + + +
Sbjct: 98 ISVLRLPPDMVWLPEIVLENNNDGSFQISYSCNVLVYHYGFVYWLPPAIFRSSCPISVTY 157
Query: 472 WXNDMQTCTFKXGSRMHNSDEM 537
+ D Q C+ K S + + E+
Sbjct: 158 FPFDWQNCSLKFSSLKYTAKEI 179
>AY159813-1|AAO38167.2| 471|Homo sapiens 5-hydroxytryptamine
serotonin receptor 3E protein.
Length = 471
Score = 50.4 bits (115), Expect = 8e-06
Identities = 26/100 (26%), Positives = 48/100 (48%), Gaps = 1/100 (1%)
Frame = +1
Query: 241 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 417
L+M W + +SWN E G + ++++ LW PD+ ++ L A VSN G +
Sbjct: 106 LEMVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEGRI 165
Query: 418 SWIKRLDISTPISMQLDNWXNDMQTCTFKXGSRMHNSDEM 537
+ K + + + ++ + + D Q CT S ++ D M
Sbjct: 166 RYKKPMKVDSICNLDIFYFPFDQQNCTLTFSSFLYTVDSM 205
>AC092165-2|AAY24102.1| 517|Homo sapiens unknown protein.
Length = 517
Score = 50.4 bits (115), Expect = 8e-06
Identities = 36/142 (25%), Positives = 65/142 (45%), Gaps = 7/142 (4%)
Frame = +1
Query: 133 YDRESPP----DSKIVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEWG- 294
Y++E P + + V L L L + +++E E T+ ++ W D RL WNA E+G
Sbjct: 38 YNKELRPVAHKEESVDVALALTLSNLISLKEVEETLTTNVWIEHGWTDNRLKWNAEEFGN 97
Query: 295 CSTWLVSSERLWRPDVVL-LNAAATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDN 471
S + + +W P++VL N + Y+ V + G V W+ + + +
Sbjct: 98 ISVLRLPPDMVWLPEIVLENNNDGSFQISYSCNVLVYHYGFVYWLPPAIFRSSCPISVTY 157
Query: 472 WXNDMQTCTFKXGSRMHNSDEM 537
+ D Q C+ K S + + E+
Sbjct: 158 FPFDWQNCSLKFSSLKYTAKEI 179
>BC111802-1|AAI11803.1| 465|Homo sapiens CHRNG protein protein.
Length = 465
Score = 49.6 bits (113), Expect = 1e-05
Identities = 33/113 (29%), Positives = 54/113 (47%), Gaps = 7/113 (6%)
Frame = +1
Query: 109 MIDSLLATYDRESPPDSKI--VVNLTLHLRHANI---RESESTVRILADLQMNWIDKRLS 273
++ L+ YD P + VVN++L L N+ E E + ++M W D RL
Sbjct: 29 LLADLMQNYDPNLRPAERDSDVVNVSLKLTLTNLISLNEREEALTTNVWIEMQWCDYRLR 88
Query: 274 WNAGEW-GCSTWLVSSERLWRPDVVLLNAAAT-TAGDYALRARVSNNGSVSWI 426
W+ ++ G V S +WRPD+VL N + T + + L+ + S+ WI
Sbjct: 89 WDPRDYEGLWVLRVPSTMVWRPDIVLENKSQTYSTNEIDLQLSQEDGQSIEWI 141
>M59216-1|AAA35862.1| 474|Homo sapiens gamma-aminobutyric acid
receptor beta-1 subunit protein.
Length = 474
Score = 49.2 bits (112), Expect = 2e-05
Identities = 39/169 (23%), Positives = 72/169 (42%), Gaps = 7/169 (4%)
Frame = +1
Query: 58 CAIASAAECENATSLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESESTV 225
C S E N + + +D LL YD PD + V + + + + + E
Sbjct: 23 CCAHSTNEPSNMSYVKETVDRLLKGYDIRLRPDFGGPPVDVGMRIDVASIDMVSEVNMDY 82
Query: 226 RILADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---AR 396
+ Q +W DKRLS++ + +++LW PD LN + ++ R
Sbjct: 83 TLTMYFQQSWKDKRLSYSGIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIR 142
Query: 397 VSNNGSVSWIKRLDISTPISMQLDNWXNDMQTCTFKXGSRMHNSDEMDF 543
+ +G+V + R+ + M L + D Q CT + S + +D+++F
Sbjct: 143 LHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEF 191
>S77554-1|AAB33983.1| 474|Homo sapiens GABAA receptor beta 2
subunit protein.
Length = 474
Score = 48.8 bits (111), Expect = 2e-05
Identities = 40/169 (23%), Positives = 72/169 (42%), Gaps = 7/169 (4%)
Frame = +1
Query: 58 CAIASAAECENATSLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESESTV 225
CA S + N + + +D LL YD PD + V + + + + + E
Sbjct: 23 CA-QSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDIASIDMVSEVNMDY 81
Query: 226 RILADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---AR 396
+ Q W DKRLS+N + +++LW PD LN + ++ R
Sbjct: 82 TLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIR 141
Query: 397 VSNNGSVSWIKRLDISTPISMQLDNWXNDMQTCTFKXGSRMHNSDEMDF 543
+ +G+V + R+ + M L + D Q CT + S + +D+++F
Sbjct: 142 LHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEF 190
>S77553-1|AAB33982.1| 512|Homo sapiens GABAA receptor beta 2
subunit protein.
Length = 512
Score = 48.8 bits (111), Expect = 2e-05
Identities = 40/169 (23%), Positives = 72/169 (42%), Gaps = 7/169 (4%)
Frame = +1
Query: 58 CAIASAAECENATSLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESESTV 225
CA S + N + + +D LL YD PD + V + + + + + E
Sbjct: 23 CA-QSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDIASIDMVSEVNMDY 81
Query: 226 RILADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---AR 396
+ Q W DKRLS+N + +++LW PD LN + ++ R
Sbjct: 82 TLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIR 141
Query: 397 VSNNGSVSWIKRLDISTPISMQLDNWXNDMQTCTFKXGSRMHNSDEMDF 543
+ +G+V + R+ + M L + D Q CT + S + +D+++F
Sbjct: 142 LHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEF 190
>S67368-1|AAB29370.1| 474|Homo sapiens gamma-aminobutyric acid A
receptor beta 2 subunit protein.
Length = 474
Score = 48.8 bits (111), Expect = 2e-05
Identities = 40/169 (23%), Positives = 72/169 (42%), Gaps = 7/169 (4%)
Frame = +1
Query: 58 CAIASAAECENATSLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESESTV 225
CA S + N + + +D LL YD PD + V + + + + + E
Sbjct: 23 CA-QSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDIASIDMVSEVNMDY 81
Query: 226 RILADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---AR 396
+ Q W DKRLS+N + +++LW PD LN + ++ R
Sbjct: 82 TLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIR 141
Query: 397 VSNNGSVSWIKRLDISTPISMQLDNWXNDMQTCTFKXGSRMHNSDEMDF 543
+ +G+V + R+ + M L + D Q CT + S + +D+++F
Sbjct: 142 LHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEF 190
>BC131799-1|AAI31800.1| 447|Homo sapiens 5-hydroxytryptamine
(serotonin) receptor 3, family member C protein.
Length = 447
Score = 48.8 bits (111), Expect = 2e-05
Identities = 24/100 (24%), Positives = 49/100 (49%), Gaps = 1/100 (1%)
Frame = +1
Query: 241 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 417
+ + W + ++WN E G + V +E LW PD+ ++ + L A +S+ G +
Sbjct: 91 MDLVWDNPFINWNPKECVGINKLTVLAENLWLPDIFIVESMDVDQTPSGLTAYISSEGRI 150
Query: 418 SWIKRLDISTPISMQLDNWXNDMQTCTFKXGSRMHNSDEM 537
+ K + +++ ++ + + D Q CTF S ++ D M
Sbjct: 151 KYDKPMRVTSICNLDIFYFPFDQQNCTFTFSSFLYTVDSM 190
>BC110597-1|AAI10598.1| 411|Homo sapiens ligand-gated ion channel,
zinc activated 1 protein.
Length = 411
Score = 48.8 bits (111), Expect = 2e-05
Identities = 26/102 (25%), Positives = 48/102 (47%)
Frame = +1
Query: 241 LQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVS 420
L+++W+D RL+WN + E LW P + +L A D + +ARV +G V
Sbjct: 86 LRLSWLDTRLAWNTSAHPRHAITLPWESLWTPRLTILEALWVDWRDQSPQARVDQDGHVK 145
Query: 421 WIKRLDISTPISMQLDNWXNDMQTCTFKXGSRMHNSDEMDFR 546
L T + +L ++ D C+ + + + E++F+
Sbjct: 146 LNLALTTETNCNFELLHFPRDHSNCSLSFYALSNTAMELEFQ 187
>BC105639-1|AAI05640.1| 474|Homo sapiens GABRB2 protein protein.
Length = 474
Score = 48.8 bits (111), Expect = 2e-05
Identities = 40/169 (23%), Positives = 72/169 (42%), Gaps = 7/169 (4%)
Frame = +1
Query: 58 CAIASAAECENATSLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESESTV 225
CA S + N + + +D LL YD PD + V + + + + + E
Sbjct: 23 CA-QSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDIASIDMVSEVNMDY 81
Query: 226 RILADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---AR 396
+ Q W DKRLS+N + +++LW PD LN + ++ R
Sbjct: 82 TLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIR 141
Query: 397 VSNNGSVSWIKRLDISTPISMQLDNWXNDMQTCTFKXGSRMHNSDEMDF 543
+ +G+V + R+ + M L + D Q CT + S + +D+++F
Sbjct: 142 LHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEF 190
>BC099719-1|AAH99719.1| 474|Homo sapiens GABRB2 protein protein.
Length = 474
Score = 48.8 bits (111), Expect = 2e-05
Identities = 40/169 (23%), Positives = 72/169 (42%), Gaps = 7/169 (4%)
Frame = +1
Query: 58 CAIASAAECENATSLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESESTV 225
CA S + N + + +D LL YD PD + V + + + + + E
Sbjct: 23 CA-QSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDIASIDMVSEVNMDY 81
Query: 226 RILADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---AR 396
+ Q W DKRLS+N + +++LW PD LN + ++ R
Sbjct: 82 TLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIR 141
Query: 397 VSNNGSVSWIKRLDISTPISMQLDNWXNDMQTCTFKXGSRMHNSDEMDF 543
+ +G+V + R+ + M L + D Q CT + S + +D+++F
Sbjct: 142 LHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEF 190
>BC099705-1|AAH99705.1| 474|Homo sapiens GABRB2 protein protein.
Length = 474
Score = 48.8 bits (111), Expect = 2e-05
Identities = 40/169 (23%), Positives = 72/169 (42%), Gaps = 7/169 (4%)
Frame = +1
Query: 58 CAIASAAECENATSLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESESTV 225
CA S + N + + +D LL YD PD + V + + + + + E
Sbjct: 23 CA-QSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDIASIDMVSEVNMDY 81
Query: 226 RILADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---AR 396
+ Q W DKRLS+N + +++LW PD LN + ++ R
Sbjct: 82 TLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIR 141
Query: 397 VSNNGSVSWIKRLDISTPISMQLDNWXNDMQTCTFKXGSRMHNSDEMDF 543
+ +G+V + R+ + M L + D Q CT + S + +D+++F
Sbjct: 142 LHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEF 190
>AF512521-1|AAO20969.1| 411|Homo sapiens ligand-gated ion channel
subunit protein.
Length = 411
Score = 48.8 bits (111), Expect = 2e-05
Identities = 26/102 (25%), Positives = 48/102 (47%)
Frame = +1
Query: 241 LQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVS 420
L+++W+D RL+WN + E LW P + +L A D + +ARV +G V
Sbjct: 86 LRLSWLDTRLAWNTSAHPRHAITLPWESLWTPRLTILEALWVDWRDQSPQARVDQDGHVK 145
Query: 421 WIKRLDISTPISMQLDNWXNDMQTCTFKXGSRMHNSDEMDFR 546
L T + +L ++ D C+ + + + E++F+
Sbjct: 146 LNLALTTETNCNFELLHFPRDHSNCSLSFYALSNTAMELEFQ 187
>X14767-1|CAA32875.1| 474|Homo sapiens GABA-A receptor beta 1
subunit protein.
Length = 474
Score = 48.4 bits (110), Expect = 3e-05
Identities = 39/169 (23%), Positives = 71/169 (42%), Gaps = 7/169 (4%)
Frame = +1
Query: 58 CAIASAAECENATSLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESESTV 225
C S E N + +D LL YD PD + V + + + + + E
Sbjct: 23 CCAHSTNEPSNMPYVKETVDRLLKGYDIRLRPDFGGPPVDVGMRIDVASIDMVSEVNMDY 82
Query: 226 RILADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---AR 396
+ Q +W DKRLS++ + +++LW PD LN + ++ R
Sbjct: 83 TLTMYFQQSWKDKRLSYSGIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIR 142
Query: 397 VSNNGSVSWIKRLDISTPISMQLDNWXNDMQTCTFKXGSRMHNSDEMDF 543
+ +G+V + R+ + M L + D Q CT + S + +D+++F
Sbjct: 143 LHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEF 191
>AY349353-1|AAQ93477.1| 456|Homo sapiens 5-HT3c1 serotonin
receptor-like protein protein.
Length = 456
Score = 48.4 bits (110), Expect = 3e-05
Identities = 26/102 (25%), Positives = 48/102 (47%), Gaps = 1/102 (0%)
Frame = +1
Query: 235 ADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNG 411
A L + W + +SWN E G + ++++ LW PD+ ++ L A VSN G
Sbjct: 89 AILDVVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEG 148
Query: 412 SVSWIKRLDISTPISMQLDNWXNDMQTCTFKXGSRMHNSDEM 537
+ + K + + + ++ + + D Q CT S ++ D M
Sbjct: 149 RIRYKKPMKVDSICNLDIFYFPFDQQNCTLTFSSFLYTVDSM 190
>AY349352-1|AAQ93476.1| 441|Homo sapiens 5-HT3c1 serotonin
receptor-like protein protein.
Length = 441
Score = 48.4 bits (110), Expect = 3e-05
Identities = 26/102 (25%), Positives = 48/102 (47%), Gaps = 1/102 (0%)
Frame = +1
Query: 235 ADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNG 411
A L + W + +SWN E G + ++++ LW PD+ ++ L A VSN G
Sbjct: 74 AILDVVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEG 133
Query: 412 SVSWIKRLDISTPISMQLDNWXNDMQTCTFKXGSRMHNSDEM 537
+ + K + + + ++ + + D Q CT S ++ D M
Sbjct: 134 RIRYKKPMKVDSICNLDIFYFPFDQQNCTLTFSSFLYTVDSM 175
>AF459285-1|AAL66182.1| 447|Homo sapiens 5-hydroxytryptamine
receptor 3 subunit C protein.
Length = 447
Score = 48.4 bits (110), Expect = 3e-05
Identities = 24/100 (24%), Positives = 48/100 (48%), Gaps = 1/100 (1%)
Frame = +1
Query: 241 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 417
+ + W + ++WN E G + V +E LW PD+ ++ + L A +S+ G +
Sbjct: 91 MDLVWDNPFINWNPKECVGINKLTVLAENLWLPDIFIVESMDVDQTPSGLTAYISSEGRI 150
Query: 418 SWIKRLDISTPISMQLDNWXNDMQTCTFKXGSRMHNSDEM 537
+ K + +++ + + + D Q CTF S ++ D M
Sbjct: 151 KYDKPMRVTSICKLDIFYFPFDQQNCTFTFSSFLYTVDSM 190
>AB223030-1|BAE19924.1| 411|Homo sapiens ligand-gated ion-channel
receptor L2 protein.
Length = 411
Score = 48.4 bits (110), Expect = 3e-05
Identities = 26/102 (25%), Positives = 48/102 (47%)
Frame = +1
Query: 241 LQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVS 420
L+++W+D RL+WN + E LW P + +L A D + +ARV +G V
Sbjct: 86 LRLSWLDTRLAWNTSAHPRHAITLPWESLWTPRLTILEALWVDWRDQSPQARVDQDGHVK 145
Query: 421 WIKRLDISTPISMQLDNWXNDMQTCTFKXGSRMHNSDEMDFR 546
L T + +L ++ D C+ + + + E++F+
Sbjct: 146 LNLALATETNCNFELLHFPRDHSNCSLSFYALSNTAMELEFQ 187
>U77731-2|AAB38273.1| 360|Homo sapiens glycine receptor alpha 2B
subunit protein.
Length = 360
Score = 46.4 bits (105), Expect = 1e-04
Identities = 38/145 (26%), Positives = 64/145 (44%), Gaps = 8/145 (5%)
Frame = +1
Query: 133 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 300
YD P+ K VN+T ++ +I E+ R+ L+ W D RL+++
Sbjct: 58 YDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDSRLAYSEYPDDSL 117
Query: 301 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLD 468
S + +W+PD+ N D R+S NG V + RL ++ M L
Sbjct: 118 DLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLK 177
Query: 469 NWXNDMQTCTFKXGSRMHNSDEMDF 543
N+ D+QTCT + S + +++ F
Sbjct: 178 NFPMDVQTCTMQLESFGYTMNDLIF 202
>CR450343-1|CAG29339.1| 452|Homo sapiens GLRA2 protein.
Length = 452
Score = 46.4 bits (105), Expect = 1e-04
Identities = 38/145 (26%), Positives = 64/145 (44%), Gaps = 8/145 (5%)
Frame = +1
Query: 133 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 300
YD P+ K VN+T ++ +I E+ R+ L+ W D RL+++
Sbjct: 58 YDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDSRLAYSEYPDDSL 117
Query: 301 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLD 468
S + +W+PD+ N D R+S NG V + RL ++ M L
Sbjct: 118 DLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLK 177
Query: 469 NWXNDMQTCTFKXGSRMHNSDEMDF 543
N+ D+QTCT + S + +++ F
Sbjct: 178 NFPMDVQTCTMQLESFGYTMNDLIF 202
>BC096083-1|AAH96083.1| 198|Homo sapiens CHRNB4 protein protein.
Length = 198
Score = 46.4 bits (105), Expect = 1e-04
Identities = 30/115 (26%), Positives = 54/115 (46%), Gaps = 8/115 (6%)
Frame = +1
Query: 61 AIASAAECENATSLSLMIDSLL--ATYDRESPP--DSKIVVNLTLHLRHA---NIRESES 219
A+ C A + ++D LL Y+ P S ++++ L L A ++ E E
Sbjct: 14 ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQ 73
Query: 220 TVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDY 381
+ L+ W D RL+WN+ + G + + ++R+W PD+VL N + T +
Sbjct: 74 IMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNKSLRTGSTW 128
>BC096081-1|AAH96081.1| 198|Homo sapiens CHRNB4 protein protein.
Length = 198
Score = 46.4 bits (105), Expect = 1e-04
Identities = 30/115 (26%), Positives = 54/115 (46%), Gaps = 8/115 (6%)
Frame = +1
Query: 61 AIASAAECENATSLSLMIDSLL--ATYDRESPP--DSKIVVNLTLHLRHA---NIRESES 219
A+ C A + ++D LL Y+ P S ++++ L L A ++ E E
Sbjct: 14 ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQ 73
Query: 220 TVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDY 381
+ L+ W D RL+WN+ + G + + ++R+W PD+VL N + T +
Sbjct: 74 IMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNKSLRTGSTW 128
>AY437084-1|AAR87843.1| 452|Homo sapiens glycine receptor alpha2
subunit B protein.
Length = 452
Score = 46.4 bits (105), Expect = 1e-04
Identities = 38/145 (26%), Positives = 64/145 (44%), Gaps = 8/145 (5%)
Frame = +1
Query: 133 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 300
YD P+ K VN+T ++ +I E+ R+ L+ W D RL+++
Sbjct: 58 YDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDSRLAYSEYPDDSL 117
Query: 301 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLD 468
S + +W+PD+ N D R+S NG V + RL ++ M L
Sbjct: 118 DLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLK 177
Query: 469 NWXNDMQTCTFKXGSRMHNSDEMDF 543
N+ D+QTCT + S + +++ F
Sbjct: 178 NFPMDVQTCTMQLESFGYTMNDLIF 202
>X52008-1|CAA36257.1| 452|Homo sapiens inhibitory glycine receptor
protein.
Length = 452
Score = 46.0 bits (104), Expect = 2e-04
Identities = 37/145 (25%), Positives = 64/145 (44%), Gaps = 8/145 (5%)
Frame = +1
Query: 133 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 300
YD P+ K VN+T ++ ++ E+ R+ L+ W D RL+++
Sbjct: 58 YDARIRPNFKGPPVNVTCNIFINSFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPDDSL 117
Query: 301 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLD 468
S + +W+PD+ N D R+S NG V + RL ++ M L
Sbjct: 118 DLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLK 177
Query: 469 NWXNDMQTCTFKXGSRMHNSDEMDF 543
N+ D+QTCT + S + +++ F
Sbjct: 178 NFPMDVQTCTMQLESFGYTMNDLIF 202
>U77731-1|AAB38272.1| 360|Homo sapiens glycine receptor alpha 2
subunit protein.
Length = 360
Score = 46.0 bits (104), Expect = 2e-04
Identities = 37/145 (25%), Positives = 64/145 (44%), Gaps = 8/145 (5%)
Frame = +1
Query: 133 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 300
YD P+ K VN+T ++ ++ E+ R+ L+ W D RL+++
Sbjct: 58 YDARIRPNFKGPPVNVTCNIFINSFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPDDSL 117
Query: 301 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLD 468
S + +W+PD+ N D R+S NG V + RL ++ M L
Sbjct: 118 DLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLK 177
Query: 469 NWXNDMQTCTFKXGSRMHNSDEMDF 543
N+ D+QTCT + S + +++ F
Sbjct: 178 NFPMDVQTCTMQLESFGYTMNDLIF 202
>BC032864-1|AAH32864.1| 452|Homo sapiens glycine receptor, alpha 2
protein.
Length = 452
Score = 46.0 bits (104), Expect = 2e-04
Identities = 37/145 (25%), Positives = 64/145 (44%), Gaps = 8/145 (5%)
Frame = +1
Query: 133 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 300
YD P+ K VN+T ++ ++ E+ R+ L+ W D RL+++
Sbjct: 58 YDARIRPNFKGPPVNVTCNIFINSFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPDDSL 117
Query: 301 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLD 468
S + +W+PD+ N D R+S NG V + RL ++ M L
Sbjct: 118 DLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLK 177
Query: 469 NWXNDMQTCTFKXGSRMHNSDEMDF 543
N+ D+QTCT + S + +++ F
Sbjct: 178 NFPMDVQTCTMQLESFGYTMNDLIF 202
>AY437083-1|AAR87842.1| 452|Homo sapiens glycine receptor alpha2
subunit A protein.
Length = 452
Score = 46.0 bits (104), Expect = 2e-04
Identities = 37/145 (25%), Positives = 64/145 (44%), Gaps = 8/145 (5%)
Frame = +1
Query: 133 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 300
YD P+ K VN+T ++ ++ E+ R+ L+ W D RL+++
Sbjct: 58 YDARIRPNFKGPPVNVTCNIFINSFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPDDSL 117
Query: 301 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLD 468
S + +W+PD+ N D R+S NG V + RL ++ M L
Sbjct: 118 DLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLK 177
Query: 469 NWXNDMQTCTFKXGSRMHNSDEMDF 543
N+ D+QTCT + S + +++ F
Sbjct: 178 NFPMDVQTCTMQLESFGYTMNDLIF 202
>AF053495-1|AAC35290.1| 452|Homo sapiens glycine receptor alpha 2
subunit protein.
Length = 452
Score = 46.0 bits (104), Expect = 2e-04
Identities = 37/145 (25%), Positives = 64/145 (44%), Gaps = 8/145 (5%)
Frame = +1
Query: 133 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 300
YD P+ K VN+T ++ ++ E+ R+ L+ W D RL+++
Sbjct: 58 YDARIRPNFKGPPVNVTCNIFINSFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPDDSL 117
Query: 301 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLD 468
S + +W+PD+ N D R+S NG V + RL ++ M L
Sbjct: 118 DLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLK 177
Query: 469 NWXNDMQTCTFKXGSRMHNSDEMDF 543
N+ D+QTCT + S + +++ F
Sbjct: 178 NFPMDVQTCTMQLESFGYTMNDLIF 202
>Z23141-1|CAA80672.1| 479|Homo sapiens cholinergic receptor,
nicotinic, alpha polypeptide 7 protein.
Length = 479
Score = 45.6 bits (103), Expect = 2e-04
Identities = 26/104 (25%), Positives = 48/104 (46%), Gaps = 2/104 (1%)
Frame = +1
Query: 241 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSNNGS 414
LQM+W D L WN E+ G T ++W+PD++L N+A + V+++G
Sbjct: 55 LQMSWTDHYLQWNVSEYPGVKTVRFPDGQIWKPDILLYNSADERFDATFHTNVLVNSSGH 114
Query: 415 VSWIKRLDISTPISMQLDNWXNDMQTCTFKXGSRMHNSDEMDFR 546
++ + + + + D+Q C K GS + +D +
Sbjct: 115 CQYLPPGIFKSSCYIDVRWFPFDVQHCKLKFGSWSYGGWSLDLQ 158
>Y08420-1|CAA69697.1| 502|Homo sapiens nicotinic acetylcholine
receptor alpha7 subunit precursor protein.
Length = 502
Score = 45.6 bits (103), Expect = 2e-04
Identities = 26/104 (25%), Positives = 48/104 (46%), Gaps = 2/104 (1%)
Frame = +1
Query: 241 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSNNGS 414
LQM+W D L WN E+ G T ++W+PD++L N+A + V+++G
Sbjct: 78 LQMSWTDHYLQWNVSEYPGVKTVRFPDGQIWKPDILLYNSADERFDATFHTNVLVNSSGH 137
Query: 415 VSWIKRLDISTPISMQLDNWXNDMQTCTFKXGSRMHNSDEMDFR 546
++ + + + + D+Q C K GS + +D +
Sbjct: 138 CQYLPPGIFKSSCYIDVRWFPFDVQHCKLKFGSWSYGGWSLDLQ 181
>X70297-1|CAA49778.1| 502|Homo sapiens neuronal nicotinic
acetylocholine receptor alpha-7 subunit protein.
Length = 502
Score = 45.6 bits (103), Expect = 2e-04
Identities = 26/104 (25%), Positives = 48/104 (46%), Gaps = 2/104 (1%)
Frame = +1
Query: 241 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSNNGS 414
LQM+W D L WN E+ G T ++W+PD++L N+A + V+++G
Sbjct: 78 LQMSWTDHYLQWNVSEYPGVKTVRFPDGQIWKPDILLYNSADERFDATFHTNVLVNSSGH 137
Query: 415 VSWIKRLDISTPISMQLDNWXNDMQTCTFKXGSRMHNSDEMDFR 546
++ + + + + D+Q C K GS + +D +
Sbjct: 138 CQYLPPGIFKSSCYIDVRWFPFDVQHCKLKFGSWSYGGWSLDLQ 181
>U62436-1|AAB40114.1| 502|Homo sapiens nicotinic acetylcholine
receptor alpha7 subunit precursor protein.
Length = 502
Score = 45.6 bits (103), Expect = 2e-04
Identities = 26/104 (25%), Positives = 48/104 (46%), Gaps = 2/104 (1%)
Frame = +1
Query: 241 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSNNGS 414
LQM+W D L WN E+ G T ++W+PD++L N+A + V+++G
Sbjct: 78 LQMSWTDHYLQWNVSEYPGVKTVRFPDGQIWKPDILLYNSADERFDATFHTNVLVNSSGH 137
Query: 415 VSWIKRLDISTPISMQLDNWXNDMQTCTFKXGSRMHNSDEMDFR 546
++ + + + + D+Q C K GS + +D +
Sbjct: 138 CQYLPPGIFKSSCYIDVRWFPFDVQHCKLKFGSWSYGGWSLDLQ 181
>AJ586911-1|CAE52911.1| 502|Homo sapiens nicotinic acetylcholine
alpha-7 subunit protein.
Length = 502
Score = 45.6 bits (103), Expect = 2e-04
Identities = 26/104 (25%), Positives = 48/104 (46%), Gaps = 2/104 (1%)
Frame = +1
Query: 241 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSNNGS 414
LQM+W D L WN E+ G T ++W+PD++L N+A + V+++G
Sbjct: 78 LQMSWTDHYLQWNVSEYPGVKTVRFPDGQIWKPDILLYNSADERFDATFHTNVLVNSSGH 137
Query: 415 VSWIKRLDISTPISMQLDNWXNDMQTCTFKXGSRMHNSDEMDFR 546
++ + + + + D+Q C K GS + +D +
Sbjct: 138 CQYLPPGIFKSSCYIDVRWFPFDVQHCKLKFGSWSYGGWSLDLQ 181
>AK122638-1|BAC85499.1| 266|Homo sapiens yte protein of 76kDa)
(LCP2). protein.
Length = 266
Score = 45.2 bits (102), Expect = 3e-04
Identities = 24/86 (27%), Positives = 40/86 (46%)
Frame = +1
Query: 241 LQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVS 420
L+++W+D RL+WN + E LW P + +L A D + +ARV +G V
Sbjct: 87 LRLSWLDTRLAWNTSAHPRHAITLPWESLWTPRLTILEALWVDWRDQSPQARVDQDGHVK 146
Query: 421 WIKRLDISTPISMQLDNWXNDMQTCT 498
L T + +L ++ D C+
Sbjct: 147 LNLALTTETNCNFELLHFPRDHSNCS 172
>U40583-1|AAA83561.1| 502|Homo sapiens alpha 7 neuronal nicotinic
acetylcholine receptor protein.
Length = 502
Score = 44.4 bits (100), Expect = 5e-04
Identities = 26/104 (25%), Positives = 47/104 (45%), Gaps = 2/104 (1%)
Frame = +1
Query: 241 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSNNGS 414
LQM+W D L WN E+ G T ++W+PD++L N+A + V+ +G
Sbjct: 78 LQMSWTDHYLQWNVSEYPGVKTVRFPDGQIWKPDILLYNSADERFDATFHTNVLVNPSGH 137
Query: 415 VSWIKRLDISTPISMQLDNWXNDMQTCTFKXGSRMHNSDEMDFR 546
++ + + + + D+Q C K GS + +D +
Sbjct: 138 CQYLPPGIFKSSCYIDVRWFPFDVQHCKLKFGSWSYGGWSLDLQ 181
>AF385585-1|AAK68111.1| 502|Homo sapiens nicotinic cholinergic
receptor alpha 7 protein.
Length = 502
Score = 44.4 bits (100), Expect = 5e-04
Identities = 26/104 (25%), Positives = 47/104 (45%), Gaps = 2/104 (1%)
Frame = +1
Query: 241 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSNNGS 414
LQM+W D L WN E+ G T ++W+PD++L N+A + V+ +G
Sbjct: 78 LQMSWTDHYLQWNVSEYPGVKTVRFPDGQIWKPDILLYNSADERFDATFHTNVLVNPSGH 137
Query: 415 VSWIKRLDISTPISMQLDNWXNDMQTCTFKXGSRMHNSDEMDFR 546
++ + + + + D+Q C K GS + +D +
Sbjct: 138 CQYLPPGIFKSSCYIDVRWFPFDVQHCKLKFGSWSYGGWSLDLQ 181
>BC022449-1|AAH22449.1| 474|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, beta 1 protein.
Length = 474
Score = 44.0 bits (99), Expect = 7e-04
Identities = 38/169 (22%), Positives = 71/169 (42%), Gaps = 7/169 (4%)
Frame = +1
Query: 58 CAIASAAECENATSLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESESTV 225
C S E N + + +D LL YD PD + V + + + + + E
Sbjct: 23 CCAHSTNEPSNMSYVKETVDRLLKGYDIRLRPDFGGPPVDVGMRIDVASIDMVSEVNMDY 82
Query: 226 RILADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---AR 396
+ Q +W DKRLS++ + +++L PD LN + ++ R
Sbjct: 83 TLTMYFQQSWKDKRLSYSGIPLNLTLDNRVADQLCVPDTYFLNDKKSFVHGVTVKNRMIR 142
Query: 397 VSNNGSVSWIKRLDISTPISMQLDNWXNDMQTCTFKXGSRMHNSDEMDF 543
+ +G+V + R+ + M L + D Q CT + S + +D+++F
Sbjct: 143 LHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEF 191
>AJ003080-1|CAA05853.1| 238|Homo sapiens serotonin receptor
protein.
Length = 238
Score = 44.0 bits (99), Expect = 7e-04
Identities = 25/111 (22%), Positives = 47/111 (42%), Gaps = 1/111 (0%)
Frame = +1
Query: 199 NIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAG 375
N+ E + + W D+ L WN ++ T L + ++ +W PD+++
Sbjct: 72 NVDEKNQVLTTYIWYRQYWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKS 131
Query: 376 DYALRARVSNNGSVSWIKRLDISTPISMQLDNWXNDMQTCTFKXGSRMHNS 528
+ + G V K L + T S+ + N+ D+Q C+ S +H S
Sbjct: 132 PNIPYVYIRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLHTS 182
>BC109211-1|AAI09212.1| 632|Homo sapiens gamma-aminobutyric acid
(GABA) receptor, theta protein.
Length = 632
Score = 43.6 bits (98), Expect = 0.001
Identities = 34/145 (23%), Positives = 59/145 (40%), Gaps = 7/145 (4%)
Frame = +1
Query: 82 CENATSLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESESTVRILADLQM 249
C N + ++D +L+ YD P+ + + V +++++ I E I
Sbjct: 53 CANEAVVQKILDRVLSRYDVRLRPNFGGAPVPVRISIYVTSIEQISEMNMDYTITMFFHQ 112
Query: 250 NWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSN---NGSVS 420
W D RL++ + E+LW PD LN+ D + RV +G+V
Sbjct: 113 TWKDSRLAYYETTLNLTLDYRMHEKLWVPDCYFLNSKDAFVHDVTVENRVFQLHPDGTVR 172
Query: 421 WIKRLDISTPISMQLDNWXNDMQTC 495
+ RL + S+ L + D Q C
Sbjct: 173 YGIRLTTTAACSLDLHKFPMDKQAC 197
>BC109210-1|AAI09211.1| 632|Homo sapiens gamma-aminobutyric acid
(GABA) receptor, theta protein.
Length = 632
Score = 43.6 bits (98), Expect = 0.001
Identities = 34/145 (23%), Positives = 59/145 (40%), Gaps = 7/145 (4%)
Frame = +1
Query: 82 CENATSLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESESTVRILADLQM 249
C N + ++D +L+ YD P+ + + V +++++ I E I
Sbjct: 53 CANEAVVQKILDRVLSRYDVRLRPNFGGAPVPVRISIYVTSIEQISEMNMDYTITMFFHQ 112
Query: 250 NWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSN---NGSVS 420
W D RL++ + E+LW PD LN+ D + RV +G+V
Sbjct: 113 TWKDSRLAYYETTLNLTLDYRMHEKLWVPDCYFLNSKDAFVHDVTVENRVFQLHPDGTVR 172
Query: 421 WIKRLDISTPISMQLDNWXNDMQTC 495
+ RL + S+ L + D Q C
Sbjct: 173 YGIRLTTTAACSLDLHKFPMDKQAC 197
>AF189259-1|AAF70380.1| 632|Homo sapiens GABA-A receptor theta
subunit protein.
Length = 632
Score = 43.6 bits (98), Expect = 0.001
Identities = 34/145 (23%), Positives = 59/145 (40%), Gaps = 7/145 (4%)
Frame = +1
Query: 82 CENATSLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESESTVRILADLQM 249
C N + ++D +L+ YD P+ + + V +++++ I E I
Sbjct: 53 CANEAVVQKILDRVLSRYDVRLRPNFGGAPVPVRISIYVTSIEQISEMNMDYTITMFFHQ 112
Query: 250 NWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSN---NGSVS 420
W D RL++ + E+LW PD LN+ D + RV +G+V
Sbjct: 113 TWKDSRLAYYETTLNLTLDYRMHEKLWVPDCYFLNSKDAFVHDVTVENRVFQLHPDGTVR 172
Query: 421 WIKRLDISTPISMQLDNWXNDMQTC 495
+ RL + S+ L + D Q C
Sbjct: 173 YGIRLTTTAACSLDLHKFPMDKQAC 197
>AF144648-1|AAD51172.1| 627|Homo sapiens GABA-A receptor theta
protein.
Length = 627
Score = 43.6 bits (98), Expect = 0.001
Identities = 34/145 (23%), Positives = 59/145 (40%), Gaps = 7/145 (4%)
Frame = +1
Query: 82 CENATSLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESESTVRILADLQM 249
C N + ++D +L+ YD P+ + + V +++++ I E I
Sbjct: 48 CANEAVVQKILDRVLSRYDVRLRPNFGGAPVPVRISIYVTSIEQISEMNMDYTITMFFHQ 107
Query: 250 NWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSN---NGSVS 420
W D RL++ + E+LW PD LN+ D + RV +G+V
Sbjct: 108 TWKDSRLAYYETTLNLTLDYRMHEKLWVPDCYFLNSKDAFVHDVTVENRVFQLHPDGTVR 167
Query: 421 WIKRLDISTPISMQLDNWXNDMQTC 495
+ RL + S+ L + D Q C
Sbjct: 168 YGIRLTTTAACSLDLHKFPMDKQAC 192
>U95367-1|AAC51357.1| 440|Homo sapiens GABA-A receptor pi subunit
protein.
Length = 440
Score = 43.2 bits (97), Expect = 0.001
Identities = 39/164 (23%), Positives = 77/164 (46%), Gaps = 9/164 (5%)
Frame = +1
Query: 79 ECENATSLSLM-IDSLLATYDRESPPD---SKIVVNLTLHLRH-ANIRESESTVRILADL 243
E + LSL ++L A Y++ P+ + + LTL + ++I ES L
Sbjct: 29 EVGRSDKLSLPGFENLTAGYNKFLRPNFGGEPVQIALTLDIASISSISESNMDYTATIYL 88
Query: 244 QMNWIDKRLSWNAGE-WGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNG 411
+ W+D+RL + + + LV E LW PD ++ + + + + R+ +NG
Sbjct: 89 RQRWMDQRLVFEGNKSFTLDARLV--EFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNG 146
Query: 412 SVSWIKRLDISTPISMQLDNWXNDMQTCTFKXGSRMHNSDEMDF 543
+V + R+ + +M L + D QTC + S ++ ++++F
Sbjct: 147 TVLYALRITTTVACNMDLSKYPMDTQTCKLQLESWGYDGNDVEF 190
>BC109106-1|AAI09107.1| 440|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, pi protein.
Length = 440
Score = 43.2 bits (97), Expect = 0.001
Identities = 39/164 (23%), Positives = 77/164 (46%), Gaps = 9/164 (5%)
Frame = +1
Query: 79 ECENATSLSLM-IDSLLATYDRESPPD---SKIVVNLTLHLRH-ANIRESESTVRILADL 243
E + LSL ++L A Y++ P+ + + LTL + ++I ES L
Sbjct: 29 EVGRSDKLSLPGFENLTAGYNKFLRPNFGGEPVQIALTLDIASISSISESNMDYTATIYL 88
Query: 244 QMNWIDKRLSWNAGE-WGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNG 411
+ W+D+RL + + + LV E LW PD ++ + + + + R+ +NG
Sbjct: 89 RQRWMDQRLVFEGNKSFTLDARLV--EFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNG 146
Query: 412 SVSWIKRLDISTPISMQLDNWXNDMQTCTFKXGSRMHNSDEMDF 543
+V + R+ + +M L + D QTC + S ++ ++++F
Sbjct: 147 TVLYALRITTTVACNMDLSKYPMDTQTCKLQLESWGYDGNDVEF 190
>BC109105-1|AAI09106.1| 440|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, pi protein.
Length = 440
Score = 43.2 bits (97), Expect = 0.001
Identities = 39/164 (23%), Positives = 77/164 (46%), Gaps = 9/164 (5%)
Frame = +1
Query: 79 ECENATSLSLM-IDSLLATYDRESPPD---SKIVVNLTLHLRH-ANIRESESTVRILADL 243
E + LSL ++L A Y++ P+ + + LTL + ++I ES L
Sbjct: 29 EVGRSDKLSLPGFENLTAGYNKFLRPNFGGEPVQIALTLDIASISSISESNMDYTATIYL 88
Query: 244 QMNWIDKRLSWNAGE-WGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNG 411
+ W+D+RL + + + LV E LW PD ++ + + + + R+ +NG
Sbjct: 89 RQRWMDQRLVFEGNKSFTLDARLV--EFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNG 146
Query: 412 SVSWIKRLDISTPISMQLDNWXNDMQTCTFKXGSRMHNSDEMDF 543
+V + R+ + +M L + D QTC + S ++ ++++F
Sbjct: 147 TVLYALRITTTVACNMDLSKYPMDTQTCKLQLESWGYDGNDVEF 190
>BC074865-1|AAH74865.1| 440|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, pi protein.
Length = 440
Score = 43.2 bits (97), Expect = 0.001
Identities = 39/164 (23%), Positives = 77/164 (46%), Gaps = 9/164 (5%)
Frame = +1
Query: 79 ECENATSLSLM-IDSLLATYDRESPPD---SKIVVNLTLHLRH-ANIRESESTVRILADL 243
E + LSL ++L A Y++ P+ + + LTL + ++I ES L
Sbjct: 29 EVGRSDKLSLPGFENLTAGYNKFLRPNFGGEPVQIALTLDIASISSISESNMDYTATIYL 88
Query: 244 QMNWIDKRLSWNAGE-WGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNG 411
+ W+D+RL + + + LV E LW PD ++ + + + + R+ +NG
Sbjct: 89 RQRWMDQRLVFEGNKSFTLDARLV--EFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNG 146
Query: 412 SVSWIKRLDISTPISMQLDNWXNDMQTCTFKXGSRMHNSDEMDF 543
+V + R+ + +M L + D QTC + S ++ ++++F
Sbjct: 147 TVLYALRITTTVACNMDLSKYPMDTQTCKLQLESWGYDGNDVEF 190
>BC074810-1|AAH74810.1| 440|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, pi protein.
Length = 440
Score = 43.2 bits (97), Expect = 0.001
Identities = 39/164 (23%), Positives = 77/164 (46%), Gaps = 9/164 (5%)
Frame = +1
Query: 79 ECENATSLSLM-IDSLLATYDRESPPD---SKIVVNLTLHLRH-ANIRESESTVRILADL 243
E + LSL ++L A Y++ P+ + + LTL + ++I ES L
Sbjct: 29 EVGRSDKLSLPGFENLTAGYNKFLRPNFGGEPVQIALTLDIASISSISESNMDYTATIYL 88
Query: 244 QMNWIDKRLSWNAGE-WGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNG 411
+ W+D+RL + + + LV E LW PD ++ + + + + R+ +NG
Sbjct: 89 RQRWMDQRLVFEGNKSFTLDARLV--EFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNG 146
Query: 412 SVSWIKRLDISTPISMQLDNWXNDMQTCTFKXGSRMHNSDEMDF 543
+V + R+ + +M L + D QTC + S ++ ++++F
Sbjct: 147 TVLYALRITTTVACNMDLSKYPMDTQTCKLQLESWGYDGNDVEF 190
>BC033801-1|AAH33801.1| 452|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, delta protein.
Length = 452
Score = 43.2 bits (97), Expect = 0.001
Identities = 37/149 (24%), Positives = 63/149 (42%), Gaps = 7/149 (4%)
Frame = +1
Query: 112 IDSLLATYDRESPPD-SKIVVNLTLHLRHANI---RESESTVRILADLQMNWIDKRLSWN 279
+D L+A Y R P VN+ L L A+I E+ + L +W D RLS+N
Sbjct: 44 LDGLIAGYARNFRPGIGGPPVNVALALEVASIDHISEANMEYTMTVFLHQSWRDSRLSYN 103
Query: 280 AGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTP 450
++LW PD ++NA + D + R+ +G + + R+ +
Sbjct: 104 HTNETLGLDSRFVDKLWLPDTFIVNAKSAWFHDVTVENKLIRLQPDGVILYSIRITSTVA 163
Query: 451 ISMQLDNWXNDMQTCTFKXGSRMHNSDEM 537
M L + D Q C S ++S+++
Sbjct: 164 CDMDLAKYPMDEQECMLDLESYGYSSEDI 192
>AL391845-4|CAI15436.1| 452|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, delta protein.
Length = 452
Score = 43.2 bits (97), Expect = 0.001
Identities = 37/149 (24%), Positives = 63/149 (42%), Gaps = 7/149 (4%)
Frame = +1
Query: 112 IDSLLATYDRESPPD-SKIVVNLTLHLRHANI---RESESTVRILADLQMNWIDKRLSWN 279
+D L+A Y R P VN+ L L A+I E+ + L +W D RLS+N
Sbjct: 44 LDGLIAGYARNFRPGIGGPPVNVALALEVASIDHISEANMEYTMTVFLHQSWRDSRLSYN 103
Query: 280 AGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTP 450
++LW PD ++NA + D + R+ +G + + R+ +
Sbjct: 104 HTNETLGLDSRFVDKLWLPDTFIVNAKSAWFHDVTVENKLIRLQPDGVILYSIRITSTVA 163
Query: 451 ISMQLDNWXNDMQTCTFKXGSRMHNSDEM 537
M L + D Q C S ++S+++
Sbjct: 164 CDMDLAKYPMDEQECMLDLESYGYSSEDI 192
>AF016917-1|AAB70007.1| 452|Homo sapiens GABA-A receptor delta
subunit protein.
Length = 452
Score = 43.2 bits (97), Expect = 0.001
Identities = 37/149 (24%), Positives = 63/149 (42%), Gaps = 7/149 (4%)
Frame = +1
Query: 112 IDSLLATYDRESPPD-SKIVVNLTLHLRHANI---RESESTVRILADLQMNWIDKRLSWN 279
+D L+A Y R P VN+ L L A+I E+ + L +W D RLS+N
Sbjct: 44 LDGLIAGYARNFRPGIGGPPVNVALALEVASIDHISEANMEYTMTVFLHQSWRDSRLSYN 103
Query: 280 AGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTP 450
++LW PD ++NA + D + R+ +G + + R+ +
Sbjct: 104 HTNETLGLDSRFVDKLWLPDTFIVNAKSAWFHDVTVENKLIRLQPDGVILYSIRITSTVA 163
Query: 451 ISMQLDNWXNDMQTCTFKXGSRMHNSDEM 537
M L + D Q C S ++S+++
Sbjct: 164 CDMDLAKYPMDEQECMLDLESYGYSSEDI 192
>AF009702-1|AAC24194.1| 440|Homo sapiens GABA-A receptor pi subunit
protein.
Length = 440
Score = 43.2 bits (97), Expect = 0.001
Identities = 39/164 (23%), Positives = 77/164 (46%), Gaps = 9/164 (5%)
Frame = +1
Query: 79 ECENATSLSLM-IDSLLATYDRESPPD---SKIVVNLTLHLRH-ANIRESESTVRILADL 243
E + LSL ++L A Y++ P+ + + LTL + ++I ES L
Sbjct: 29 EVGRSDKLSLPGFENLTAGYNKFLRPNFGGEPVQIALTLDIASISSISESNMDYTATIYL 88
Query: 244 QMNWIDKRLSWNAGE-WGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNG 411
+ W+D+RL + + + LV E LW PD ++ + + + + R+ +NG
Sbjct: 89 RQRWMDQRLVFEGNKSFTLDARLV--EFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNG 146
Query: 412 SVSWIKRLDISTPISMQLDNWXNDMQTCTFKXGSRMHNSDEMDF 543
+V + R+ + +M L + D QTC + S ++ ++++F
Sbjct: 147 TVLYALRITTTVACNMDLSKYPMDTQTCKLQLESWGYDGNDVEF 190
>X52009-1|CAA36258.1| 449|Homo sapiens inhibitory glycine receptor
protein.
Length = 449
Score = 41.1 bits (92), Expect = 0.005
Identities = 29/119 (24%), Positives = 53/119 (44%), Gaps = 4/119 (3%)
Frame = +1
Query: 199 NIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERLWRPDVVLLNAAATTAG 375
+I E+ R+ L+ W D RL++N S + +W+PD+ N
Sbjct: 78 SIAETTMDYRVNIFLRQQWNDPRLAYNEYPDDSLDLDPSMLDSIWKPDLFFANEKGAHFH 137
Query: 376 DYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWXNDMQTCTFKXGSRMHNSDEMDF 543
+ R+S NG+V + R+ ++ M L N+ D+QTC + S + +++ F
Sbjct: 138 EITTDNKLLRISRNGNVLYSIRITLTLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIF 196
>BC114947-1|AAI14948.1| 457|Homo sapiens GLRA1 protein protein.
Length = 457
Score = 41.1 bits (92), Expect = 0.005
Identities = 29/119 (24%), Positives = 53/119 (44%), Gaps = 4/119 (3%)
Frame = +1
Query: 199 NIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERLWRPDVVLLNAAATTAG 375
+I E+ R+ L+ W D RL++N S + +W+PD+ N
Sbjct: 78 SIAETTMDYRVNIFLRQQWNDPRLAYNEYPDDSLDLDPSMLDSIWKPDLFFANEKGAHFH 137
Query: 376 DYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWXNDMQTCTFKXGSRMHNSDEMDF 543
+ R+S NG+V + R+ ++ M L N+ D+QTC + S + +++ F
Sbjct: 138 EITTDNKLLRISRNGNVLYSIRITLTLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIF 196
>BC074980-1|AAH74980.1| 449|Homo sapiens glycine receptor, alpha 1
(startle disease/hyperekplexia) protein.
Length = 449
Score = 41.1 bits (92), Expect = 0.005
Identities = 29/119 (24%), Positives = 53/119 (44%), Gaps = 4/119 (3%)
Frame = +1
Query: 199 NIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERLWRPDVVLLNAAATTAG 375
+I E+ R+ L+ W D RL++N S + +W+PD+ N
Sbjct: 78 SIAETTMDYRVNIFLRQQWNDPRLAYNEYPDDSLDLDPSMLDSIWKPDLFFANEKGAHFH 137
Query: 376 DYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWXNDMQTCTFKXGSRMHNSDEMDF 543
+ R+S NG+V + R+ ++ M L N+ D+QTC + S + +++ F
Sbjct: 138 EITTDNKLLRISRNGNVLYSIRITLTLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIF 196
>U93917-1|AAC39917.1| 449|Homo sapiens glycine receptor alpha 3
subunit protein.
Length = 449
Score = 40.3 bits (90), Expect = 0.009
Identities = 38/154 (24%), Positives = 67/154 (43%), Gaps = 8/154 (5%)
Frame = +1
Query: 133 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 300
YD P+ K VN+T ++ +I E+ R+ L+ W D RL+++
Sbjct: 57 YDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPDDSL 116
Query: 301 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLD 468
S + +W+PD+ N + R+ NG+V + RL ++ M L
Sbjct: 117 DLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLK 176
Query: 469 NWXNDMQTCTFKXGSRMHNSDEMDFRD*QXNIPV 570
N+ D+QTC + S + +++ F + Q PV
Sbjct: 177 NFPMDVQTCIMQLESFGYTMNDLIF-EWQDEAPV 209
>BC036086-1|AAH36086.1| 464|Homo sapiens glycine receptor, alpha 3
protein.
Length = 464
Score = 40.3 bits (90), Expect = 0.009
Identities = 38/154 (24%), Positives = 67/154 (43%), Gaps = 8/154 (5%)
Frame = +1
Query: 133 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 300
YD P+ K VN+T ++ +I E+ R+ L+ W D RL+++
Sbjct: 57 YDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPDDSL 116
Query: 301 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLD 468
S + +W+PD+ N + R+ NG+V + RL ++ M L
Sbjct: 117 DLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLK 176
Query: 469 NWXNDMQTCTFKXGSRMHNSDEMDFRD*QXNIPV 570
N+ D+QTC + S + +++ F + Q PV
Sbjct: 177 NFPMDVQTCIMQLESFGYTMNDLIF-EWQDEAPV 209
>AF017724-1|AAC39919.1| 465|Homo sapiens glycine receptor alpha 3
subunit protein.
Length = 465
Score = 40.3 bits (90), Expect = 0.009
Identities = 38/154 (24%), Positives = 67/154 (43%), Gaps = 8/154 (5%)
Frame = +1
Query: 133 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 300
YD P+ K VN+T ++ +I E+ R+ L+ W D RL+++
Sbjct: 57 YDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPDDSL 116
Query: 301 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLD 468
S + +W+PD+ N + R+ NG+V + RL ++ M L
Sbjct: 117 DLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLK 176
Query: 469 NWXNDMQTCTFKXGSRMHNSDEMDFRD*QXNIPV 570
N+ D+QTC + S + +++ F + Q PV
Sbjct: 177 NFPMDVQTCIMQLESFGYTMNDLIF-EWQDEAPV 209
>Z93848-1|CAI41994.1| 376|Homo sapiens glycine receptor, alpha 4
protein.
Length = 376
Score = 39.9 bits (89), Expect = 0.011
Identities = 36/145 (24%), Positives = 62/145 (42%), Gaps = 8/145 (5%)
Frame = +1
Query: 133 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 300
YD P+ K VN+T ++ ++I ++ R+ L+ W D RLS+
Sbjct: 17 YDARIRPNFKGPPVNVTCNIFINSFSSITKTTMDYRVNVFLRQQWNDPRLSYREYPDDSL 76
Query: 301 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLD 468
S + +W+PD+ N + R+ NG+V + RL + M L
Sbjct: 77 DLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLILSCLMDLK 136
Query: 469 NWXNDMQTCTFKXGSRMHNSDEMDF 543
N+ D+QTCT + S + ++ F
Sbjct: 137 NFPMDIQTCTMQLESFGYTMKDLVF 161
>AL049610-1|CAI42158.1| 376|Homo sapiens glycine receptor, alpha 4
protein.
Length = 376
Score = 39.9 bits (89), Expect = 0.011
Identities = 36/145 (24%), Positives = 62/145 (42%), Gaps = 8/145 (5%)
Frame = +1
Query: 133 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 300
YD P+ K VN+T ++ ++I ++ R+ L+ W D RLS+
Sbjct: 17 YDARIRPNFKGPPVNVTCNIFINSFSSITKTTMDYRVNVFLRQQWNDPRLSYREYPDDSL 76
Query: 301 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLD 468
S + +W+PD+ N + R+ NG+V + RL + M L
Sbjct: 77 DLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLILSCLMDLK 136
Query: 469 NWXNDMQTCTFKXGSRMHNSDEMDF 543
N+ D+QTCT + S + ++ F
Sbjct: 137 NFPMDIQTCTMQLESFGYTMKDLVF 161
>BC114967-1|AAI14968.1| 366|Homo sapiens GLRA1 protein protein.
Length = 366
Score = 38.7 bits (86), Expect = 0.026
Identities = 27/110 (24%), Positives = 49/110 (44%), Gaps = 4/110 (3%)
Frame = +1
Query: 226 RILADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERLWRPDVVLLNAAATTAGDYALR---A 393
R+ L+ W D RL++N S + +W+PD+ N +
Sbjct: 4 RVNIFLRQQWNDPRLAYNEYPDDSLDLDPSMLDSIWKPDLFFANEKGAHFHEITTDNKLL 63
Query: 394 RVSNNGSVSWIKRLDISTPISMQLDNWXNDMQTCTFKXGSRMHNSDEMDF 543
R+S NG+V + R+ ++ M L N+ D+QTC + S + +++ F
Sbjct: 64 RISRNGNVLYSIRITLTLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIF 113
>BC146774-1|AAI46775.1| 1114|Homo sapiens GPR124 protein protein.
Length = 1114
Score = 30.7 bits (66), Expect = 6.9
Identities = 16/55 (29%), Positives = 26/55 (47%), Gaps = 1/55 (1%)
Frame = +1
Query: 274 WNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNN-GSVSWIKRL 435
W +GEW C+ + + ++V+L T+ Y RV+NN G W + L
Sbjct: 314 WASGEWECTVSMAQGNASKKVEIVVLE----TSASYCPAERVANNRGDFRWPRTL 364
>AY181242-1|AAO27354.1| 1331|Homo sapiens G protein-coupled receptor
124 protein.
Length = 1331
Score = 30.7 bits (66), Expect = 6.9
Identities = 16/55 (29%), Positives = 26/55 (47%), Gaps = 1/55 (1%)
Frame = +1
Query: 274 WNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNN-GSVSWIKRL 435
W +GEW C+ + + ++V+L T+ Y RV+NN G W + L
Sbjct: 314 WASGEWECTVSMAQGNASKKVEIVVLE----TSASYCPAERVANNRGDFRWPRTL 364
>AK074099-1|BAB84925.1| 1310|Homo sapiens FLJ00170 protein protein.
Length = 1310
Score = 30.7 bits (66), Expect = 6.9
Identities = 16/55 (29%), Positives = 26/55 (47%), Gaps = 1/55 (1%)
Frame = +1
Query: 274 WNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNN-GSVSWIKRL 435
W +GEW C+ + + ++V+L T+ Y RV+NN G W + L
Sbjct: 293 WASGEWECTVSMAQGNASKKVEIVVLE----TSASYCPAERVANNRGDFRWPRTL 343
>AF378755-1|AAL11992.1| 1331|Homo sapiens tumor endothelial marker 5
precursor protein.
Length = 1331
Score = 30.7 bits (66), Expect = 6.9
Identities = 16/55 (29%), Positives = 26/55 (47%), Gaps = 1/55 (1%)
Frame = +1
Query: 274 WNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNN-GSVSWIKRL 435
W +GEW C+ + + ++V+L T+ Y RV+NN G W + L
Sbjct: 314 WASGEWECTVSMAQGNASKKVEIVVLE----TSASYCPAERVANNRGDFRWPRTL 364
>AB040964-1|BAA96055.2| 1206|Homo sapiens KIAA1531 protein protein.
Length = 1206
Score = 30.7 bits (66), Expect = 6.9
Identities = 16/55 (29%), Positives = 26/55 (47%), Gaps = 1/55 (1%)
Frame = +1
Query: 274 WNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNN-GSVSWIKRL 435
W +GEW C+ + + ++V+L T+ Y RV+NN G W + L
Sbjct: 406 WASGEWECTVSMAQGNASKKVEIVVLE----TSASYCPAERVANNRGDFRWPRTL 456
>AB209359-1|BAD92596.1| 533|Homo sapiens cholinergic receptor,
nicotinic, alpha polypeptide 4 precursor variant
protein.
Length = 533
Score = 30.3 bits (65), Expect = 9.1
Identities = 17/72 (23%), Positives = 31/72 (43%)
Frame = +1
Query: 325 LWRPDVVLLNAAATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWXNDMQTCTFK 504
LW +A A + +A + ++G V W + S+ + + D Q CT K
Sbjct: 25 LWLCCCTFTSADGDFAVTHLTKAHLFHDGRVQWTPPAIYKSSCSIDVTFFPFDQQNCTMK 84
Query: 505 XGSRMHNSDEMD 540
GS ++ ++D
Sbjct: 85 FGSWTYDKAKID 96
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 116,872,580
Number of Sequences: 237096
Number of extensions: 2560782
Number of successful extensions: 6594
Number of sequences better than 10.0: 150
Number of HSP's better than 10.0 without gapping: 5990
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 6467
length of database: 76,859,062
effective HSP length: 89
effective length of database: 55,757,518
effective search space used: 10649685938
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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