Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BmNP09_FL5_P06
(821 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
AJ306454-1|CAC34819.1| 497|Homo sapiens neuronal nicotinic acet... 73 1e-12
Y08416-1|CAA69693.1| 498|Homo sapiens nicotinic acetylcholine r... 71 4e-12
U62439-1|AAB40117.1| 498|Homo sapiens nicotinic acetylcholine r... 71 4e-12
U48861-1|AAA92123.1| 498|Homo sapiens beta 4 nicotinic acetylch... 71 4e-12
BC096082-1|AAH96082.1| 498|Homo sapiens cholinergic receptor, n... 71 4e-12
BC096080-1|AAH96080.1| 498|Homo sapiens cholinergic receptor, n... 71 4e-12
AF306329-1|AAL02062.1| 498|Homo sapiens neuronal nicotinic acet... 71 4e-12
X68275-1|CAA48336.1| 451|Homo sapiens nicotinic receptor beta 4... 67 8e-11
Y08417-1|CAA69694.1| 458|Homo sapiens nicotinic acetylcholine r... 64 4e-10
X67513-1|CAA47851.1| 423|Homo sapiens nicotinic acetylcholine ... 64 4e-10
U62438-1|AAB40116.1| 458|Homo sapiens nicotinic acetylcholine r... 64 4e-10
BT006897-1|AAP35543.1| 505|Homo sapiens cholinergic receptor, n... 64 4e-10
BT006646-1|AAP35292.1| 489|Homo sapiens cholinergic receptor, n... 64 4e-10
BC069788-1|AAH69788.1| 458|Homo sapiens cholinergic receptor, n... 64 4e-10
BC069703-1|AAH69703.1| 458|Homo sapiens cholinergic receptor, n... 64 4e-10
BC069681-1|AAH69681.1| 458|Homo sapiens cholinergic receptor, n... 64 4e-10
BC006114-1|AAH06114.1| 489|Homo sapiens CHRNA3 protein protein. 64 4e-10
BC002996-1|AAH02996.1| 505|Homo sapiens cholinergic receptor, n... 64 4e-10
BC001642-1|AAH01642.1| 505|Homo sapiens cholinergic receptor, n... 64 4e-10
BC000513-1|AAH00513.1| 505|Homo sapiens cholinergic receptor, n... 64 4e-10
AF385584-1|AAK68110.1| 489|Homo sapiens nicotinic cholinergic r... 64 4e-10
AF140765-1|AAD33063.1| 458|Homo sapiens neuronal acetylcholine ... 64 4e-10
Y08418-1|CAA69695.1| 503|Homo sapiens nicotinic acetylcholine r... 64 8e-10
X14830-1|CAA32939.1| 501|Homo sapiens protein ( Human mRNA for ... 64 8e-10
U62432-1|AAB40110.1| 504|Homo sapiens nicotinic acetylcholine r... 64 8e-10
M37981-1|AAA59942.1| 503|Homo sapiens neuronal nicotinic acetyl... 64 8e-10
BC098443-1|AAH98443.1| 504|Homo sapiens cholinergic receptor, n... 64 8e-10
BC011371-1|AAH11371.1| 501|Homo sapiens cholinergic receptor, n... 64 8e-10
AJ007783-1|CAA07682.1| 504|Homo sapiens nicotinic acetylcholine... 64 8e-10
Y16281-1|CAA76154.1| 529|Homo sapiens nicotinic acetylcholine r... 62 2e-09
Y00762-1|CAA68731.1| 457|Homo sapiens protein ( Human mRNA for ... 62 2e-09
X02502-1|CAA26344.1| 457|Homo sapiens acetylcholine receptor pr... 62 2e-09
U62431-1|AAB40109.1| 529|Homo sapiens nicotinic acetylcholine r... 62 2e-09
S77094-1|AAD14247.1| 457|Homo sapiens nicotinic acetylcholine r... 62 2e-09
BC023553-1|AAH23553.1| 501|Homo sapiens cholinergic receptor, n... 62 2e-09
BC006314-1|AAH06314.1| 269|Homo sapiens CHRNA1 protein protein. 62 2e-09
AC018890-1|AAY14687.1| 457|Homo sapiens unknown protein. 62 2e-09
Y08419-1|CAA69696.1| 468|Homo sapiens nicotinic acetylcholine r... 62 2e-09
X53559-1|CAA37625.1| 474|Homo sapiens neuronal nicotinic acetyl... 62 2e-09
U62434-1|AAB40112.1| 468|Homo sapiens nicotinic acetylcholine r... 62 2e-09
BC033639-1|AAH33639.1| 468|Homo sapiens cholinergic receptor, n... 62 2e-09
AJ306481-1|CAC34820.1| 468|Homo sapiens neuronal nicotinic acet... 62 2e-09
Y16282-1|CAA76155.1| 494|Homo sapiens nicotinic acetylcholine r... 62 3e-09
U62435-1|AAB40113.1| 494|Homo sapiens nicotinic acetylcholine r... 62 3e-09
BC014456-1|AAH14456.1| 494|Homo sapiens cholinergic receptor, n... 62 3e-09
AB079251-1|BAC06855.1| 494|Homo sapiens Nicotinic acetylcholine... 62 3e-09
M86383-1|AAC84176.1| 502|Homo sapiens nicotinic acetylcholine r... 61 4e-09
M83712-1|AAA58357.1| 468|Homo sapiens nicotinic receptor alpha ... 61 5e-09
X01715-1|CAA25861.1| 520|Homo sapiens acetylcholine receptor ga... 60 7e-09
AC092165-3|AAY24103.1| 520|Homo sapiens unknown protein. 60 7e-09
X66403-1|CAA47030.1| 493|Homo sapiens acetylcholine receptor ep... 60 1e-08
AF105999-1|AAD24503.1| 493|Homo sapiens acetylcholine receptor ... 60 1e-08
Y08421-1|CAA69698.1| 627|Homo sapiens nicotinic acetylcholine r... 60 1e-08
X89741-1|CAA61893.1| 627|Homo sapiens neuronal acetylcholine re... 60 1e-08
U62433-1|AAB40111.1| 627|Homo sapiens nicotinic acetylcholine r... 60 1e-08
L35901-1|AAA64743.1| 627|Homo sapiens nicotinic acetylcholine r... 60 1e-08
DQ093071-1|AAY88737.1| 627|Homo sapiens cholinergic receptor, n... 60 1e-08
BC096290-1|AAH96290.1| 627|Homo sapiens cholinergic receptor, n... 60 1e-08
AJ001935-1|CAA05108.1| 504|Homo sapiens CHRNB2 protein. 60 1e-08
Y08415-1|CAA69692.1| 502|Homo sapiens nicotinic acetylcholine r... 59 2e-08
X87629-1|CAA60959.1| 602|Homo sapiens nicotinic acetylcholine r... 59 2e-08
X53179-1|CAA37320.1| 502|Homo sapiens precursor peptide (AA -25... 59 2e-08
U62437-1|AAB40115.1| 502|Homo sapiens nicotinic acetylcholine r... 59 2e-08
BC075041-1|AAH75041.1| 502|Homo sapiens cholinergic receptor, n... 59 2e-08
BC075040-1|AAH75040.1| 502|Homo sapiens cholinergic receptor, n... 59 2e-08
AL592078-3|CAI16184.1| 502|Homo sapiens cholinergic receptor, n... 59 2e-08
AF077186-1|AAD45422.1| 502|Homo sapiens neuronal nicotinic acet... 59 2e-08
X55019-1|CAA38759.1| 517|Homo sapiens acetylcholine receptor de... 57 9e-08
BC093925-1|AAH93925.1| 517|Homo sapiens cholinergic receptor, n... 57 9e-08
BC093923-1|AAH93923.1| 517|Homo sapiens cholinergic receptor, n... 57 9e-08
AJ295237-1|CAC16144.1| 450|Homo sapiens neuronal nicotinic acet... 57 9e-08
AJ278118-1|CAC20435.1| 450|Homo sapiens neuronal nicotinic acet... 57 9e-08
AF327367-1|AAK14333.1| 450|Homo sapiens nicotinic acetylcholine... 57 9e-08
AF199235-1|AAG00795.2| 450|Homo sapiens nicotinic acetylcholine... 57 9e-08
AC092165-2|AAY24102.1| 517|Homo sapiens unknown protein. 57 9e-08
DQ644022-1|ABG35128.1| 456|Homo sapiens 5-HT3 receptor subunit ... 56 2e-07
BC101185-1|AAI01186.1| 374|Homo sapiens HTR3E protein protein. 56 2e-07
BC101183-1|AAI01184.1| 471|Homo sapiens 5-hydroxytryptamine (se... 56 2e-07
BC101182-1|AAI01183.1| 471|Homo sapiens 5-hydroxytryptamine (se... 56 2e-07
AY159813-1|AAO38167.2| 471|Homo sapiens 5-hydroxytryptamine ser... 56 2e-07
BC111802-1|AAI11803.1| 465|Homo sapiens CHRNG protein protein. 55 4e-07
L08485-1|AAA58490.1| 462|Homo sapiens GABA-benzodiazepine recep... 54 5e-07
BT009830-1|AAP88832.1| 462|Homo sapiens gamma-aminobutyric acid... 54 5e-07
BC131799-1|AAI31800.1| 447|Homo sapiens 5-hydroxytryptamine (se... 54 5e-07
BC113422-1|AAI13423.1| 462|Homo sapiens gamma-aminobutyric acid... 54 5e-07
BC111979-1|AAI11980.1| 462|Homo sapiens gamma-aminobutyric acid... 54 5e-07
AY349353-1|AAQ93477.1| 456|Homo sapiens 5-HT3c1 serotonin recep... 54 5e-07
AY349352-1|AAQ93476.1| 441|Homo sapiens 5-HT3c1 serotonin recep... 54 5e-07
AF459285-1|AAL66182.1| 447|Homo sapiens 5-hydroxytryptamine rec... 54 6e-07
Z23141-1|CAA80672.1| 479|Homo sapiens cholinergic receptor, nic... 54 8e-07
Y08420-1|CAA69697.1| 502|Homo sapiens nicotinic acetylcholine r... 54 8e-07
X70297-1|CAA49778.1| 502|Homo sapiens neuronal nicotinic acetyl... 54 8e-07
U62436-1|AAB40114.1| 502|Homo sapiens nicotinic acetylcholine r... 54 8e-07
S82769-1|AAB39369.1| 467|Homo sapiens GABAA receptor gamma 3 su... 54 8e-07
AJ586911-1|CAE52911.1| 502|Homo sapiens nicotinic acetylcholine... 54 8e-07
AF269144-1|AAF99698.1| 467|Homo sapiens GABAA receptor gamma 3 ... 54 8e-07
AF228458-1|AAF63215.1| 449|Homo sapiens GABAA receptor gamma 3 ... 54 8e-07
BC110597-1|AAI10598.1| 411|Homo sapiens ligand-gated ion channe... 53 1e-06
AF512521-1|AAO20969.1| 411|Homo sapiens ligand-gated ion channe... 53 1e-06
AB223030-1|BAE19924.1| 411|Homo sapiens ligand-gated ion-channe... 53 1e-06
S77554-1|AAB33983.1| 474|Homo sapiens GABAA receptor beta 2 sub... 52 2e-06
S77553-1|AAB33982.1| 512|Homo sapiens GABAA receptor beta 2 sub... 52 2e-06
S67368-1|AAB29370.1| 474|Homo sapiens gamma-aminobutyric acid A... 52 2e-06
BC105639-1|AAI05640.1| 474|Homo sapiens GABRB2 protein protein. 52 2e-06
BC099719-1|AAH99719.1| 474|Homo sapiens GABRB2 protein protein. 52 2e-06
BC099705-1|AAH99705.1| 474|Homo sapiens GABRB2 protein protein. 52 2e-06
BC028629-1|AAH28629.1| 492|Homo sapiens gamma-aminobutyric acid... 52 2e-06
AJ003080-1|CAA05853.1| 238|Homo sapiens serotonin receptor prot... 52 2e-06
U40583-1|AAA83561.1| 502|Homo sapiens alpha 7 neuronal nicotini... 52 3e-06
S82612-1|AAB37533.2| 478|Homo sapiens 5-hydroxytryptamine type ... 52 3e-06
S62908-1|AAB27279.1| 492|Homo sapiens gamma-aminobutyric acidA ... 52 3e-06
M59216-1|AAA35862.1| 474|Homo sapiens gamma-aminobutyric acid r... 52 3e-06
AF385585-1|AAK68111.1| 502|Homo sapiens nicotinic cholinergic r... 52 3e-06
AF166361-1|AAG12455.1| 492|Homo sapiens GABA receptor subunit a... 52 3e-06
X14767-1|CAA32875.1| 474|Homo sapiens GABA-A receptor beta 1 su... 51 4e-06
D49394-1|BAA08387.1| 478|Homo sapiens serotonin 5-HT3 receptor ... 51 4e-06
BT007204-1|AAP35868.1| 484|Homo sapiens 5-hydroxytryptamine (se... 51 4e-06
BC113575-1|AAI13576.1| 479|Homo sapiens cholinergic receptor, n... 51 4e-06
BC113549-1|AAI13550.1| 479|Homo sapiens cholinergic receptor, n... 51 4e-06
BC004453-1|AAH04453.2| 478|Homo sapiens 5-hydroxytryptamine (se... 51 4e-06
BC002354-1|AAH02354.1| 478|Homo sapiens 5-hydroxytryptamine (se... 51 4e-06
AY123244-1|AAM74523.1| 479|Homo sapiens nicotinic acetylcholine... 51 4e-06
AJ243342-1|CAB65091.1| 479|Homo sapiens nicotinic acetylcholine... 51 4e-06
AJ005205-1|CAA06442.3| 478|Homo sapiens serotonin 3 receptor pr... 51 4e-06
AJ003079-1|CAA05852.1| 478|Homo sapiens 5-hydroxytryptamine3 re... 51 4e-06
AJ003078-1|CAA05851.1| 510|Homo sapiens serotonin receptor prot... 51 4e-06
AF498984-1|AAM21131.1| 478|Homo sapiens 5-hydroxytryptamine rec... 51 4e-06
AF227732-1|AAF61920.1| 470|Homo sapiens nicotinic acetylcholine... 51 4e-06
AC118275-1|AAY40986.1| 479|Homo sapiens unknown protein. 51 4e-06
U77731-2|AAB38273.1| 360|Homo sapiens glycine receptor alpha 2B... 51 6e-06
CR450343-1|CAG29339.1| 452|Homo sapiens GLRA2 protein. 51 6e-06
AY437084-1|AAR87843.1| 452|Homo sapiens glycine receptor alpha2... 51 6e-06
AK122638-1|BAC85499.1| 266|Homo sapiens yte protein of 76kDa) (... 51 6e-06
X52008-1|CAA36257.1| 452|Homo sapiens inhibitory glycine recept... 50 8e-06
U77731-1|AAB38272.1| 360|Homo sapiens glycine receptor alpha 2 ... 50 8e-06
S81944-1|AAB36480.1| 453|Homo sapiens gamma-aminobutyric acid t... 50 8e-06
BC099641-1|AAH99641.1| 453|Homo sapiens gamma-aminobutyric acid... 50 8e-06
BC099640-1|AAH99640.1| 453|Homo sapiens gamma-aminobutyric acid... 50 8e-06
BC096242-1|AAH96242.1| 453|Homo sapiens gamma-aminobutyric acid... 50 8e-06
BC096241-1|AAH96241.1| 453|Homo sapiens gamma-aminobutyric acid... 50 8e-06
BC032864-1|AAH32864.1| 452|Homo sapiens glycine receptor, alpha... 50 8e-06
AY437083-1|AAR87842.1| 452|Homo sapiens glycine receptor alpha2... 50 8e-06
AF053495-1|AAC35290.1| 452|Homo sapiens glycine receptor alpha ... 50 8e-06
U30461-1|AAB52519.1| 554|Homo sapiens GABAA receptor subunit al... 50 1e-05
BC035055-1|AAH35055.1| 554|Homo sapiens gamma-aminobutyric acid... 50 1e-05
BC096083-1|AAH96083.1| 198|Homo sapiens CHRNB4 protein protein. 48 4e-05
BC096081-1|AAH96081.1| 198|Homo sapiens CHRNB4 protein protein. 48 4e-05
BC033801-1|AAH33801.1| 452|Homo sapiens gamma-aminobutyric acid... 47 7e-05
AL391845-4|CAI15436.1| 452|Homo sapiens gamma-aminobutyric acid... 47 7e-05
AF016917-1|AAB70007.1| 452|Homo sapiens GABA-A receptor delta s... 47 7e-05
U93917-1|AAC39917.1| 449|Homo sapiens glycine receptor alpha 3 ... 47 9e-05
BC114947-1|AAI14948.1| 457|Homo sapiens GLRA1 protein protein. 47 9e-05
BC074980-1|AAH74980.1| 449|Homo sapiens glycine receptor, alpha... 47 9e-05
BC036086-1|AAH36086.1| 464|Homo sapiens glycine receptor, alpha... 47 9e-05
BC022449-1|AAH22449.1| 474|Homo sapiens gamma-aminobutyric acid... 47 9e-05
AF017724-1|AAC39919.1| 465|Homo sapiens glycine receptor alpha ... 47 9e-05
X52009-1|CAA36258.1| 449|Homo sapiens inhibitory glycine recept... 46 1e-04
BC109211-1|AAI09212.1| 632|Homo sapiens gamma-aminobutyric acid... 46 2e-04
BC109210-1|AAI09211.1| 632|Homo sapiens gamma-aminobutyric acid... 46 2e-04
AF189259-1|AAF70380.1| 632|Homo sapiens GABA-A receptor theta s... 46 2e-04
AF144648-1|AAD51172.1| 627|Homo sapiens GABA-A receptor theta p... 46 2e-04
BC074795-1|AAH74795.1| 467|Homo sapiens gamma-aminobutyric acid... 45 3e-04
BC069348-1|AAH69348.1| 467|Homo sapiens gamma-aminobutyric acid... 45 3e-04
BC059389-1|AAH59389.1| 475|Homo sapiens gamma-aminobutyric acid... 45 3e-04
AF165124-1|AAD50273.1| 467|Homo sapiens gamma-aminobutyric acid... 45 3e-04
U95367-1|AAC51357.1| 440|Homo sapiens GABA-A receptor pi subuni... 45 4e-04
BC109106-1|AAI09107.1| 440|Homo sapiens gamma-aminobutyric acid... 45 4e-04
BC109105-1|AAI09106.1| 440|Homo sapiens gamma-aminobutyric acid... 45 4e-04
BC074865-1|AAH74865.1| 440|Homo sapiens gamma-aminobutyric acid... 45 4e-04
BC074810-1|AAH74810.1| 440|Homo sapiens gamma-aminobutyric acid... 45 4e-04
AF009702-1|AAC24194.1| 440|Homo sapiens GABA-A receptor pi subu... 45 4e-04
Z93848-1|CAI41994.1| 376|Homo sapiens glycine receptor, alpha 4... 44 5e-04
BC031087-1|AAH31087.1| 465|Homo sapiens gamma-aminobutyric acid... 44 5e-04
AL049610-1|CAI42158.1| 376|Homo sapiens glycine receptor, alpha... 44 5e-04
X15376-1|CAA33437.1| 467|Homo sapiens GABA-A receptor gamma 2 s... 44 7e-04
BC114967-1|AAI14968.1| 366|Homo sapiens GLRA1 protein protein. 44 7e-04
AB209359-1|BAD92596.1| 533|Homo sapiens cholinergic receptor, n... 34 0.54
BC096291-1|AAH96291.1| 556|Homo sapiens CHRNA4 protein protein. 33 0.94
U83981-1|AAC25631.1| 674|Homo sapiens apoptosis associated prot... 31 5.0
CR457259-1|CAG33540.1| 674|Homo sapiens PPP1R15A protein. 31 5.0
BC003067-1|AAH03067.1| 674|Homo sapiens protein phosphatase 1, ... 31 5.0
AK001361-1|BAA91649.1| 674|Homo sapiens protein ( Homo sapiens ... 31 5.0
BC146774-1|AAI46775.1| 1114|Homo sapiens GPR124 protein protein. 31 6.7
AY181242-1|AAO27354.1| 1331|Homo sapiens G protein-coupled recep... 31 6.7
AK074099-1|BAB84925.1| 1310|Homo sapiens FLJ00170 protein protein. 31 6.7
AF378755-1|AAL11992.1| 1331|Homo sapiens tumor endothelial marke... 31 6.7
AB040964-1|BAA96055.2| 1206|Homo sapiens KIAA1531 protein protein. 31 6.7
AK122582-1|BAC56923.1| 1383|Homo sapiens FLJ00269 protein protein. 30 8.8
>AJ306454-1|CAC34819.1| 497|Homo sapiens neuronal nicotinic
acetylcholine receptor beta-4 subunit protein.
Length = 497
Score = 73.3 bits (172), Expect = 1e-12
Identities = 54/200 (27%), Positives = 87/200 (43%), Gaps = 10/200 (5%)
Frame = +2
Query: 41 LLPFLLTCAIASAAECENATSLSLMIDSLL--ATYD---RDSPPDSKIV-VNLTLHLRHA 202
L+ F L A+ C A + ++D LL Y+ R + S+++ + L L L
Sbjct: 7 LVLFFLV-ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQL 65
Query: 203 -NIRESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTA 376
++ E E + L+ W D RL+WN+ + G + + ++R+W PD+VL N T
Sbjct: 66 ISVNEREQIMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNDGTYE 125
Query: 377 GDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRM--HXSDEMXFR 550
V +NGSV W+ + +++ +P D Q CT KF S H +M
Sbjct: 126 VSVYTNLIVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRSWTYDHTEIDMVLM 185
Query: 551 D*XKEYTXCPXPGXWDVTAL 610
G WD+ AL
Sbjct: 186 TPTASMDDFTPSGEWDIVAL 205
>Y08416-1|CAA69693.1| 498|Homo sapiens nicotinic acetylcholine
receptor beta4 subunit precursor protein.
Length = 498
Score = 71.3 bits (167), Expect = 4e-12
Identities = 55/201 (27%), Positives = 88/201 (43%), Gaps = 11/201 (5%)
Frame = +2
Query: 41 LLPFLLTCAIASAAECENATSLSLMIDSLL--ATYD---RDSPPDSKIV-VNLTLHLRHA 202
L+ F L A+ C A + ++D LL Y+ R + S+++ + L L L
Sbjct: 7 LVLFFLV-ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQL 65
Query: 203 -NIRESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATT 373
++ E E + L+ W D RL+WN+ + G + + ++R+W PD+VL N A T
Sbjct: 66 ISVNEREQIMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNADGTY 125
Query: 374 AGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRM--HXSDEMXF 547
V +NGSV W+ + +++ +P D Q CT KF S H +M
Sbjct: 126 EVSVYTNLIVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRSWTYDHTEIDMVL 185
Query: 548 RD*XKEYTXCPXPGXWDVTAL 610
G WD+ AL
Sbjct: 186 MTPTASMDDFTPSGEWDIVAL 206
>U62439-1|AAB40117.1| 498|Homo sapiens nicotinic acetylcholine
receptor beta4 subunit precursor protein.
Length = 498
Score = 71.3 bits (167), Expect = 4e-12
Identities = 55/201 (27%), Positives = 88/201 (43%), Gaps = 11/201 (5%)
Frame = +2
Query: 41 LLPFLLTCAIASAAECENATSLSLMIDSLL--ATYD---RDSPPDSKIV-VNLTLHLRHA 202
L+ F L A+ C A + ++D LL Y+ R + S+++ + L L L
Sbjct: 7 LVLFFLV-ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQL 65
Query: 203 -NIRESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATT 373
++ E E + L+ W D RL+WN+ + G + + ++R+W PD+VL N A T
Sbjct: 66 ISVNEREQIMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNADGTY 125
Query: 374 AGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRM--HXSDEMXF 547
V +NGSV W+ + +++ +P D Q CT KF S H +M
Sbjct: 126 EVSVYTNLIVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRSWTYDHTEIDMVL 185
Query: 548 RD*XKEYTXCPXPGXWDVTAL 610
G WD+ AL
Sbjct: 186 MTPTASMDDFTPSGEWDIVAL 206
>U48861-1|AAA92123.1| 498|Homo sapiens beta 4 nicotinic
acetylcholine receptor subunit protein.
Length = 498
Score = 71.3 bits (167), Expect = 4e-12
Identities = 55/201 (27%), Positives = 88/201 (43%), Gaps = 11/201 (5%)
Frame = +2
Query: 41 LLPFLLTCAIASAAECENATSLSLMIDSLL--ATYD---RDSPPDSKIV-VNLTLHLRHA 202
L+ F L A+ C A + ++D LL Y+ R + S+++ + L L L
Sbjct: 7 LVLFFLV-ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQL 65
Query: 203 -NIRESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATT 373
++ E E + L+ W D RL+WN+ + G + + ++R+W PD+VL N A T
Sbjct: 66 ISVNEREQIMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNADGTY 125
Query: 374 AGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRM--HXSDEMXF 547
V +NGSV W+ + +++ +P D Q CT KF S H +M
Sbjct: 126 EVSVYTNLIVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRSWTYDHTEIDMVL 185
Query: 548 RD*XKEYTXCPXPGXWDVTAL 610
G WD+ AL
Sbjct: 186 MTPTASMDDFTPSGEWDIVAL 206
>BC096082-1|AAH96082.1| 498|Homo sapiens cholinergic receptor,
nicotinic, beta 4 protein.
Length = 498
Score = 71.3 bits (167), Expect = 4e-12
Identities = 55/201 (27%), Positives = 88/201 (43%), Gaps = 11/201 (5%)
Frame = +2
Query: 41 LLPFLLTCAIASAAECENATSLSLMIDSLL--ATYD---RDSPPDSKIV-VNLTLHLRHA 202
L+ F L A+ C A + ++D LL Y+ R + S+++ + L L L
Sbjct: 7 LVLFFLV-ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQL 65
Query: 203 -NIRESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATT 373
++ E E + L+ W D RL+WN+ + G + + ++R+W PD+VL N A T
Sbjct: 66 ISVNEREQIMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNADGTY 125
Query: 374 AGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRM--HXSDEMXF 547
V +NGSV W+ + +++ +P D Q CT KF S H +M
Sbjct: 126 EVSVYTNLIVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRSWTYDHTEIDMVL 185
Query: 548 RD*XKEYTXCPXPGXWDVTAL 610
G WD+ AL
Sbjct: 186 MTPTASMDDFTPSGEWDIVAL 206
>BC096080-1|AAH96080.1| 498|Homo sapiens cholinergic receptor,
nicotinic, beta 4 protein.
Length = 498
Score = 71.3 bits (167), Expect = 4e-12
Identities = 55/201 (27%), Positives = 88/201 (43%), Gaps = 11/201 (5%)
Frame = +2
Query: 41 LLPFLLTCAIASAAECENATSLSLMIDSLL--ATYD---RDSPPDSKIV-VNLTLHLRHA 202
L+ F L A+ C A + ++D LL Y+ R + S+++ + L L L
Sbjct: 7 LVLFFLV-ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQL 65
Query: 203 -NIRESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATT 373
++ E E + L+ W D RL+WN+ + G + + ++R+W PD+VL N A T
Sbjct: 66 ISVNEREQIMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNADGTY 125
Query: 374 AGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRM--HXSDEMXF 547
V +NGSV W+ + +++ +P D Q CT KF S H +M
Sbjct: 126 EVSVYTNLIVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRSWTYDHTEIDMVL 185
Query: 548 RD*XKEYTXCPXPGXWDVTAL 610
G WD+ AL
Sbjct: 186 MTPTASMDDFTPSGEWDIVAL 206
>AF306329-1|AAL02062.1| 498|Homo sapiens neuronal nicotinic
acetylcholine receptor beta 4 subunit protein.
Length = 498
Score = 71.3 bits (167), Expect = 4e-12
Identities = 55/201 (27%), Positives = 88/201 (43%), Gaps = 11/201 (5%)
Frame = +2
Query: 41 LLPFLLTCAIASAAECENATSLSLMIDSLL--ATYD---RDSPPDSKIV-VNLTLHLRHA 202
L+ F L A+ C A + ++D LL Y+ R + S+++ + L L L
Sbjct: 7 LVLFFLV-ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQL 65
Query: 203 -NIRESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATT 373
++ E E + L+ W D RL+WN+ + G + + ++R+W PD+VL N A T
Sbjct: 66 ISVNEREQIMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNADGTY 125
Query: 374 AGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRM--HXSDEMXF 547
V +NGSV W+ + +++ +P D Q CT KF S H +M
Sbjct: 126 EVSVYTNLIVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRSWTYDHTEIDMVL 185
Query: 548 RD*XKEYTXCPXPGXWDVTAL 610
G WD+ AL
Sbjct: 186 MTPTASMDDFTPSGEWDIVAL 206
>X68275-1|CAA48336.1| 451|Homo sapiens nicotinic receptor beta 4
subunit protein.
Length = 451
Score = 66.9 bits (156), Expect = 8e-11
Identities = 43/153 (28%), Positives = 67/153 (43%), Gaps = 5/153 (3%)
Frame = +2
Query: 167 IVVNLTLHLRHA-NIRESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 340
I + L L L ++ E + + L+ W D RL+WN+ + G + + ++R+W P
Sbjct: 7 ISIKLQLSLAQLISVNERDEIMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLP 66
Query: 341 DVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 517
D+VL N A T V +NGSV W+ + +++ +P D Q CT KF S
Sbjct: 67 DIVLYNNADGTYEVSVYTNLIVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRS 126
Query: 518 RM--HXSDEMXFRD*XKEYTXCPXPGXWDVTAL 610
H +M G WD+ AL
Sbjct: 127 WTYDHTEIDMVLMTPTASMDDFTPSGEWDIVAL 159
>Y08417-1|CAA69694.1| 458|Homo sapiens nicotinic acetylcholine
receptor beta3 subunit precursor protein.
Length = 458
Score = 64.5 bits (150), Expect = 4e-10
Identities = 34/107 (31%), Positives = 51/107 (47%), Gaps = 2/107 (1%)
Frame = +2
Query: 203 NIRESESTVRIQADLQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLL-NAAATTA 376
++ E + L+ W D +L WN ++G + V SE LW PD+VL NA
Sbjct: 67 DVDEKNQLMTTNVWLKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFE 126
Query: 377 GDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 517
G + V +NG+V W + +M + +P D Q C+ KFGS
Sbjct: 127 GSLMTKVIVKSNGTVVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGS 173
>X67513-1|CAA47851.1| 423|Homo sapiens nicotinic acetylcholine
receptor beta-3 subunit protein.
Length = 423
Score = 64.5 bits (150), Expect = 4e-10
Identities = 34/107 (31%), Positives = 51/107 (47%), Gaps = 2/107 (1%)
Frame = +2
Query: 203 NIRESESTVRIQADLQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLL-NAAATTA 376
++ E + L+ W D +L WN ++G + V SE LW PD+VL NA
Sbjct: 32 DVDEKNQLMTTNVWLKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFE 91
Query: 377 GDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 517
G + V +NG+V W + +M + +P D Q C+ KFGS
Sbjct: 92 GSLMTKVIVKSNGTVVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGS 138
>U62438-1|AAB40116.1| 458|Homo sapiens nicotinic acetylcholine
receptor beta3 subunit precursor protein.
Length = 458
Score = 64.5 bits (150), Expect = 4e-10
Identities = 34/107 (31%), Positives = 51/107 (47%), Gaps = 2/107 (1%)
Frame = +2
Query: 203 NIRESESTVRIQADLQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLL-NAAATTA 376
++ E + L+ W D +L WN ++G + V SE LW PD+VL NA
Sbjct: 67 DVDEKNQLMTTNVWLKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFE 126
Query: 377 GDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 517
G + V +NG+V W + +M + +P D Q C+ KFGS
Sbjct: 127 GSLMTKVIVKSNGTVVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGS 173
>BT006897-1|AAP35543.1| 505|Homo sapiens cholinergic receptor,
nicotinic, alpha polypeptide 3 protein.
Length = 505
Score = 64.5 bits (150), Expect = 4e-10
Identities = 43/171 (25%), Positives = 79/171 (46%), Gaps = 5/171 (2%)
Frame = +2
Query: 20 MSTTYIILLPFLLTCAIASAAECENATSLSLMID--SLLATYDRDSPPDSKIVVNLTLHL 193
+S ++LL L +A A+E E+ L D ++ S P ++++ + +
Sbjct: 12 LSPPRLLLLLLLSLLPVARASEAEHRLFERLFEDYNEIIRPVANVSDP---VIIHFEVSM 68
Query: 194 RH-ANIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AA 364
+ E + L+ W D +L WN ++G + ++ V ++++W+PD+VL N A
Sbjct: 69 SQLVKVDEVNQIMETNLWLKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAV 128
Query: 365 ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 517
D +A + G V+WI + + + +P D Q CT KFGS
Sbjct: 129 GDFQVDDKTKALLKYTGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGS 179
>BT006646-1|AAP35292.1| 489|Homo sapiens cholinergic receptor,
nicotinic, alpha polypeptide 3 protein.
Length = 489
Score = 64.5 bits (150), Expect = 4e-10
Identities = 43/171 (25%), Positives = 79/171 (46%), Gaps = 5/171 (2%)
Frame = +2
Query: 20 MSTTYIILLPFLLTCAIASAAECENATSLSLMID--SLLATYDRDSPPDSKIVVNLTLHL 193
+S ++LL L +A A+E E+ L D ++ S P ++++ + +
Sbjct: 12 LSPPRLLLLLLLSLLPVARASEAEHRLFERLFEDYNEIIRPVANVSDP---VIIHFEVSM 68
Query: 194 RH-ANIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AA 364
+ E + L+ W D +L WN ++G + ++ V ++++W+PD+VL N A
Sbjct: 69 SQLVKVDEVNQIMETNLWLKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAV 128
Query: 365 ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 517
D +A + G V+WI + + + +P D Q CT KFGS
Sbjct: 129 GDFQVDDKTKALLKYTGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGS 179
>BC069788-1|AAH69788.1| 458|Homo sapiens cholinergic receptor,
nicotinic, beta 3 protein.
Length = 458
Score = 64.5 bits (150), Expect = 4e-10
Identities = 34/107 (31%), Positives = 51/107 (47%), Gaps = 2/107 (1%)
Frame = +2
Query: 203 NIRESESTVRIQADLQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLL-NAAATTA 376
++ E + L+ W D +L WN ++G + V SE LW PD+VL NA
Sbjct: 67 DVDEKNQLMTTNVWLKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFE 126
Query: 377 GDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 517
G + V +NG+V W + +M + +P D Q C+ KFGS
Sbjct: 127 GSLMTKVIVKSNGTVVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGS 173
>BC069703-1|AAH69703.1| 458|Homo sapiens cholinergic receptor,
nicotinic, beta 3 protein.
Length = 458
Score = 64.5 bits (150), Expect = 4e-10
Identities = 34/107 (31%), Positives = 51/107 (47%), Gaps = 2/107 (1%)
Frame = +2
Query: 203 NIRESESTVRIQADLQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLL-NAAATTA 376
++ E + L+ W D +L WN ++G + V SE LW PD+VL NA
Sbjct: 67 DVDEKNQLMTTNVWLKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFE 126
Query: 377 GDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 517
G + V +NG+V W + +M + +P D Q C+ KFGS
Sbjct: 127 GSLMTKVIVKSNGTVVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGS 173
>BC069681-1|AAH69681.1| 458|Homo sapiens cholinergic receptor,
nicotinic, beta 3 protein.
Length = 458
Score = 64.5 bits (150), Expect = 4e-10
Identities = 34/107 (31%), Positives = 51/107 (47%), Gaps = 2/107 (1%)
Frame = +2
Query: 203 NIRESESTVRIQADLQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLL-NAAATTA 376
++ E + L+ W D +L WN ++G + V SE LW PD+VL NA
Sbjct: 67 DVDEKNQLMTTNVWLKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFE 126
Query: 377 GDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 517
G + V +NG+V W + +M + +P D Q C+ KFGS
Sbjct: 127 GSLMTKVIVKSNGTVVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGS 173
>BC006114-1|AAH06114.1| 489|Homo sapiens CHRNA3 protein protein.
Length = 489
Score = 64.5 bits (150), Expect = 4e-10
Identities = 43/171 (25%), Positives = 79/171 (46%), Gaps = 5/171 (2%)
Frame = +2
Query: 20 MSTTYIILLPFLLTCAIASAAECENATSLSLMID--SLLATYDRDSPPDSKIVVNLTLHL 193
+S ++LL L +A A+E E+ L D ++ S P ++++ + +
Sbjct: 12 LSPPRLLLLLLLSLLPVARASEAEHRLFERLFEDYNEIIRPVANVSDP---VIIHFEVSM 68
Query: 194 RH-ANIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AA 364
+ E + L+ W D +L WN ++G + ++ V ++++W+PD+VL N A
Sbjct: 69 SQLVKVDEVNQIMETNLWLKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAV 128
Query: 365 ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 517
D +A + G V+WI + + + +P D Q CT KFGS
Sbjct: 129 GDFQVDDKTKALLKYTGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGS 179
>BC002996-1|AAH02996.1| 505|Homo sapiens cholinergic receptor,
nicotinic, alpha 3 protein.
Length = 505
Score = 64.5 bits (150), Expect = 4e-10
Identities = 43/171 (25%), Positives = 79/171 (46%), Gaps = 5/171 (2%)
Frame = +2
Query: 20 MSTTYIILLPFLLTCAIASAAECENATSLSLMID--SLLATYDRDSPPDSKIVVNLTLHL 193
+S ++LL L +A A+E E+ L D ++ S P ++++ + +
Sbjct: 12 LSPPRLLLLLLLSLLPVARASEAEHRLFERLFEDYNEIIRPVANVSDP---VIIHFEVSM 68
Query: 194 RH-ANIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AA 364
+ E + L+ W D +L WN ++G + ++ V ++++W+PD+VL N A
Sbjct: 69 SQLVKVDEVNQIMETNLWLKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAV 128
Query: 365 ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 517
D +A + G V+WI + + + +P D Q CT KFGS
Sbjct: 129 GDFQVDDKTKALLKYTGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGS 179
>BC001642-1|AAH01642.1| 505|Homo sapiens cholinergic receptor,
nicotinic, alpha 3 protein.
Length = 505
Score = 64.5 bits (150), Expect = 4e-10
Identities = 43/171 (25%), Positives = 79/171 (46%), Gaps = 5/171 (2%)
Frame = +2
Query: 20 MSTTYIILLPFLLTCAIASAAECENATSLSLMID--SLLATYDRDSPPDSKIVVNLTLHL 193
+S ++LL L +A A+E E+ L D ++ S P ++++ + +
Sbjct: 12 LSPPRLLLLLLLSLLPVARASEAEHRLFERLFEDYNEIIRPVANVSDP---VIIHFEVSM 68
Query: 194 RH-ANIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AA 364
+ E + L+ W D +L WN ++G + ++ V ++++W+PD+VL N A
Sbjct: 69 SQLVKVDEVNQIMETNLWLKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAV 128
Query: 365 ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 517
D +A + G V+WI + + + +P D Q CT KFGS
Sbjct: 129 GDFQVDDKTKALLKYTGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGS 179
>BC000513-1|AAH00513.1| 505|Homo sapiens cholinergic receptor,
nicotinic, alpha 3 protein.
Length = 505
Score = 64.5 bits (150), Expect = 4e-10
Identities = 43/171 (25%), Positives = 79/171 (46%), Gaps = 5/171 (2%)
Frame = +2
Query: 20 MSTTYIILLPFLLTCAIASAAECENATSLSLMID--SLLATYDRDSPPDSKIVVNLTLHL 193
+S ++LL L +A A+E E+ L D ++ S P ++++ + +
Sbjct: 12 LSPPRLLLLLLLSLLPVARASEAEHRLFERLFEDYNEIIRPVANVSDP---VIIHFEVSM 68
Query: 194 RH-ANIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AA 364
+ E + L+ W D +L WN ++G + ++ V ++++W+PD+VL N A
Sbjct: 69 SQLVKVDEVNQIMETNLWLKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAV 128
Query: 365 ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 517
D +A + G V+WI + + + +P D Q CT KFGS
Sbjct: 129 GDFQVDDKTKALLKYTGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGS 179
>AF385584-1|AAK68110.1| 489|Homo sapiens nicotinic cholinergic
receptor alpha 3 protein.
Length = 489
Score = 64.5 bits (150), Expect = 4e-10
Identities = 43/171 (25%), Positives = 79/171 (46%), Gaps = 5/171 (2%)
Frame = +2
Query: 20 MSTTYIILLPFLLTCAIASAAECENATSLSLMID--SLLATYDRDSPPDSKIVVNLTLHL 193
+S ++LL L +A A+E E+ L D ++ S P ++++ + +
Sbjct: 6 LSPPRLLLLLLLSLLPVARASEAEHRLFERLFEDYNEIIRPVANVSDP---VIIHFEVSM 62
Query: 194 RH-ANIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AA 364
+ E + L+ W D +L WN ++G + ++ V ++++W+PD+VL N A
Sbjct: 63 SQLVKVDEVNQIMETNLWLKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAV 122
Query: 365 ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 517
D +A + G V+WI + + + +P D Q CT KFGS
Sbjct: 123 GDFQVDDKTKALLKYTGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGS 173
>AF140765-1|AAD33063.1| 458|Homo sapiens neuronal acetylcholine
receptor beta-3 subunit precursor protein.
Length = 458
Score = 64.5 bits (150), Expect = 4e-10
Identities = 34/107 (31%), Positives = 51/107 (47%), Gaps = 2/107 (1%)
Frame = +2
Query: 203 NIRESESTVRIQADLQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLL-NAAATTA 376
++ E + L+ W D +L WN ++G + V SE LW PD+VL NA
Sbjct: 67 DVDEKNQLMTTNVWLKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFE 126
Query: 377 GDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 517
G + V +NG+V W + +M + +P D Q C+ KFGS
Sbjct: 127 GSLMTKVIVKSNGTVVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGS 173
>Y08418-1|CAA69695.1| 503|Homo sapiens nicotinic acetylcholine
receptor alpha3 subunit precursor protein.
Length = 503
Score = 63.7 bits (148), Expect = 8e-10
Identities = 43/164 (26%), Positives = 76/164 (46%), Gaps = 3/164 (1%)
Frame = +2
Query: 35 IILLPFLLTCAIASAAECENATSLSLMIDSLLATYDRDSPPDSKIVVNLTLHLRH-ANIR 211
++LL LL A AS AE L + ++ S P ++++ + + +
Sbjct: 17 LLLLLSLLPVARASEAEHRLFERLFEDYNEIIRPVANVSDP---VIIHFEVSMSQLVKVD 73
Query: 212 ESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDY 385
E + L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D
Sbjct: 74 EVNQIMETNLWLKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDD 133
Query: 386 ALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 517
+A + G V+WI + + + +P D Q CT KFGS
Sbjct: 134 KTKALLKYTGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGS 177
>X14830-1|CAA32939.1| 501|Homo sapiens protein ( Human mRNA for
muscle acetylcholine receptor beta-subunit. ).
Length = 501
Score = 63.7 bits (148), Expect = 8e-10
Identities = 45/130 (34%), Positives = 67/130 (51%), Gaps = 4/130 (3%)
Frame = +2
Query: 164 KIVVNLTL-HLRHANIRESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWR 337
++ V L L L N ++ E + ++ DL+ W D RLSW+ E G + +++E +W
Sbjct: 53 RVSVGLILAQLISLNEKDEEMSTKVYLDLE--WTDYRLSWDPAEHDGIDSLRITAESVWL 110
Query: 338 PDVVLLNAAATTAGDYAL--RARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKF 511
PDVVLLN D AL VS++GSV W + S+Q+ +P D Q CT F
Sbjct: 111 PDVVLLNNNDGNF-DVALDISVVVSSDGSVRWQPPGIYRSSCSIQVTYFPFDWQNCTMVF 169
Query: 512 GSRMHXSDEM 541
S + S E+
Sbjct: 170 SSYSYDSSEV 179
>U62432-1|AAB40110.1| 504|Homo sapiens nicotinic acetylcholine
receptor alpha3 subunit precursor protein.
Length = 504
Score = 63.7 bits (148), Expect = 8e-10
Identities = 43/164 (26%), Positives = 76/164 (46%), Gaps = 3/164 (1%)
Frame = +2
Query: 35 IILLPFLLTCAIASAAECENATSLSLMIDSLLATYDRDSPPDSKIVVNLTLHLRH-ANIR 211
++LL LL A AS AE L + ++ S P ++++ + + +
Sbjct: 18 LLLLLSLLPVARASEAEHRLFERLFEDYNEIIRPVANVSDP---VIIHFEVSMSQLVKVD 74
Query: 212 ESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDY 385
E + L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D
Sbjct: 75 EVNQIMETNLWLKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDD 134
Query: 386 ALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 517
+A + G V+WI + + + +P D Q CT KFGS
Sbjct: 135 KTKALLKYTGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGS 178
>M37981-1|AAA59942.1| 503|Homo sapiens neuronal nicotinic
acetylcholine receptor protein.
Length = 503
Score = 63.7 bits (148), Expect = 8e-10
Identities = 43/164 (26%), Positives = 76/164 (46%), Gaps = 3/164 (1%)
Frame = +2
Query: 35 IILLPFLLTCAIASAAECENATSLSLMIDSLLATYDRDSPPDSKIVVNLTLHLRH-ANIR 211
++LL LL A AS AE L + ++ S P ++++ + + +
Sbjct: 17 LLLLLSLLPVARASEAEHRLFERLFEDYNEIIRPVANVSDP---VIIHFEVSMSQLVKVD 73
Query: 212 ESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDY 385
E + L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D
Sbjct: 74 EVNQIMETNLWLKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDD 133
Query: 386 ALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 517
+A + G V+WI + + + +P D Q CT KFGS
Sbjct: 134 KTKALLKYTGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGS 177
>BC098443-1|AAH98443.1| 504|Homo sapiens cholinergic receptor,
nicotinic, alpha 3 protein.
Length = 504
Score = 63.7 bits (148), Expect = 8e-10
Identities = 43/164 (26%), Positives = 76/164 (46%), Gaps = 3/164 (1%)
Frame = +2
Query: 35 IILLPFLLTCAIASAAECENATSLSLMIDSLLATYDRDSPPDSKIVVNLTLHLRH-ANIR 211
++LL LL A AS AE L + ++ S P ++++ + + +
Sbjct: 18 LLLLLSLLPVARASEAEHRLFERLFEDYNEIIRPVANVSDP---VIIHFEVSMSQLVKVD 74
Query: 212 ESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDY 385
E + L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D
Sbjct: 75 EVNQIMETNLWLKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDD 134
Query: 386 ALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 517
+A + G V+WI + + + +P D Q CT KFGS
Sbjct: 135 KTKALLKYTGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGS 178
>BC011371-1|AAH11371.1| 501|Homo sapiens cholinergic receptor,
nicotinic, beta 1 (muscle) protein.
Length = 501
Score = 63.7 bits (148), Expect = 8e-10
Identities = 45/130 (34%), Positives = 67/130 (51%), Gaps = 4/130 (3%)
Frame = +2
Query: 164 KIVVNLTL-HLRHANIRESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWR 337
++ V L L L N ++ E + ++ DL+ W D RLSW+ E G + +++E +W
Sbjct: 53 RVSVGLILAQLISLNEKDEEMSTKVYLDLE--WTDYRLSWDPAEHDGIDSLRITAESVWL 110
Query: 338 PDVVLLNAAATTAGDYAL--RARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKF 511
PDVVLLN D AL VS++GSV W + S+Q+ +P D Q CT F
Sbjct: 111 PDVVLLNNNDGNF-DVALDISVVVSSDGSVRWQPPGIYRSSCSIQVTYFPFDWQNCTMVF 169
Query: 512 GSRMHXSDEM 541
S + S E+
Sbjct: 170 SSYSYDSSEV 179
>AJ007783-1|CAA07682.1| 504|Homo sapiens nicotinic acetylcholine
receptor alpha-3 subunit protein.
Length = 504
Score = 63.7 bits (148), Expect = 8e-10
Identities = 43/164 (26%), Positives = 76/164 (46%), Gaps = 3/164 (1%)
Frame = +2
Query: 35 IILLPFLLTCAIASAAECENATSLSLMIDSLLATYDRDSPPDSKIVVNLTLHLRH-ANIR 211
++LL LL A AS AE L + ++ S P ++++ + + +
Sbjct: 18 LLLLLSLLPVARASEAEHRLFERLFEDYNEIIRPVANVSDP---VIIHFEVSMSQLVKVD 74
Query: 212 ESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDY 385
E + L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D
Sbjct: 75 EVNQIMETNLWLKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDD 134
Query: 386 ALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 517
+A + G V+WI + + + +P D Q CT KFGS
Sbjct: 135 KTKALLKYTGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGS 178
>Y16281-1|CAA76154.1| 529|Homo sapiens nicotinic acetylcholine
receptor alpha2 subunit precursor protein.
Length = 529
Score = 62.5 bits (145), Expect = 2e-09
Identities = 34/107 (31%), Positives = 53/107 (49%), Gaps = 2/107 (1%)
Frame = +2
Query: 203 NIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAA-ATTA 376
++ E + L+ W D +L WN ++G T L V SE +W PD+VL N A A
Sbjct: 97 DVDEKNQMMTTNVWLKQEWSDYKLRWNPADFGNITSLRVPSEMIWIPDIVLYNNADGEFA 156
Query: 377 GDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 517
+ +A + + G+V W+ + S+ + +P D Q C KFGS
Sbjct: 157 VTHMTKAHLFSTGTVHWVPPAIYKSSCSIDVTFFPFDQQNCKMKFGS 203
>Y00762-1|CAA68731.1| 457|Homo sapiens protein ( Human mRNA for
muscle acetylcholine receptor alpha-subunit. ).
Length = 457
Score = 62.5 bits (145), Expect = 2e-09
Identities = 44/167 (26%), Positives = 77/167 (46%), Gaps = 10/167 (5%)
Frame = +2
Query: 47 PFLLTCAIASAAECENATSLSLMIDSLLATYDRDSPP--DSKIVVNLTLHLRHA---NIR 211
P LL ++ SA + + ++ L Y P D + VV +T+ L+ N+
Sbjct: 5 PLLLLFSLCSAGLVLGSEHETRLVAKLFKDYSSVVRPVEDHRQVVEVTVGLQLIQLINVD 64
Query: 212 ESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYA 388
E V L+ W+D L WN ++G + + SE++WRPD+VL N A GD+A
Sbjct: 65 EVNQIVTTNVRLKQQWVDYNLKWNPDDYGGVKKIHIPSEKIWRPDLVLYNNA---DGDFA 121
Query: 389 L----RARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 517
+ + + G ++W + + + ++P D Q C+ K G+
Sbjct: 122 IVKFTKVLLQYTGHITWTPPAIFKSYCEIIVTHFPFDEQNCSMKLGT 168
>X02502-1|CAA26344.1| 457|Homo sapiens acetylcholine receptor
protein.
Length = 457
Score = 62.5 bits (145), Expect = 2e-09
Identities = 44/167 (26%), Positives = 77/167 (46%), Gaps = 10/167 (5%)
Frame = +2
Query: 47 PFLLTCAIASAAECENATSLSLMIDSLLATYDRDSPP--DSKIVVNLTLHLRHA---NIR 211
P LL ++ SA + + ++ L Y P D + VV +T+ L+ N+
Sbjct: 5 PLLLLFSLCSAGLVLGSEHETRLVAKLFKDYSSVVRPVEDHRQVVEVTVGLQLIQLINVD 64
Query: 212 ESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYA 388
E V L+ W+D L WN ++G + + SE++WRPD+VL N A GD+A
Sbjct: 65 EVNQIVTTNVRLKQQWVDYNLKWNPDDYGGVKKIHIPSEKIWRPDLVLYNNA---DGDFA 121
Query: 389 L----RARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 517
+ + + G ++W + + + ++P D Q C+ K G+
Sbjct: 122 IVKFTKVLLQYTGHITWTPPAIFKSYCEIIVTHFPFDEQNCSMKLGT 168
>U62431-1|AAB40109.1| 529|Homo sapiens nicotinic acetylcholine
receptor alpha2 subunit precursor protein.
Length = 529
Score = 62.5 bits (145), Expect = 2e-09
Identities = 34/107 (31%), Positives = 53/107 (49%), Gaps = 2/107 (1%)
Frame = +2
Query: 203 NIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAA-ATTA 376
++ E + L+ W D +L WN ++G T L V SE +W PD+VL N A A
Sbjct: 97 DVDEKNQMMTTNVWLKQEWSDYKLRWNPADFGNITSLRVPSEMIWIPDIVLYNNADGEFA 156
Query: 377 GDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 517
+ +A + + G+V W+ + S+ + +P D Q C KFGS
Sbjct: 157 VTHMTKAHLFSTGTVHWVPPAIYKSSCSIDVTFFPFDQQNCKMKFGS 203
>S77094-1|AAD14247.1| 457|Homo sapiens nicotinic acetylcholine
receptor alpha subunit|AChR protein.
Length = 457
Score = 62.5 bits (145), Expect = 2e-09
Identities = 44/167 (26%), Positives = 77/167 (46%), Gaps = 10/167 (5%)
Frame = +2
Query: 47 PFLLTCAIASAAECENATSLSLMIDSLLATYDRDSPP--DSKIVVNLTLHLRHA---NIR 211
P LL ++ SA + + ++ L Y P D + VV +T+ L+ N+
Sbjct: 5 PLLLLFSLCSAGLVLGSEHETRLVAKLFKDYSSVVRPVEDHRQVVEVTVGLQLIQLINVD 64
Query: 212 ESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYA 388
E V L+ W+D L WN ++G + + SE++WRPD+VL N A GD+A
Sbjct: 65 EVNQIVTTNVRLKQQWVDYNLKWNPDDYGGVKKIHIPSEKIWRPDLVLYNNA---DGDFA 121
Query: 389 L----RARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 517
+ + + G ++W + + + ++P D Q C+ K G+
Sbjct: 122 IVKFTKVLLQYTGHITWTPPAIFKSYCEIIVTHFPFDEQNCSMKLGT 168
>BC023553-1|AAH23553.1| 501|Homo sapiens cholinergic receptor,
nicotinic, beta 1 (muscle) protein.
Length = 501
Score = 62.5 bits (145), Expect = 2e-09
Identities = 43/132 (32%), Positives = 68/132 (51%), Gaps = 6/132 (4%)
Frame = +2
Query: 164 KIVVNLTL-HLRHANIRESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWR 337
++ V L L L N ++ E + ++ DL+ W D RLSW+ E G + +++E +W
Sbjct: 53 RVSVGLILAQLISLNEKDEEMSTKVYLDLE--WTDYRLSWDPAEHDGIDSLRITAESVWL 110
Query: 338 PDVVLLNAAATTAGDY----ALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTF 505
PDVVLLN G++ + VS++GSV W + S+Q+ +P D Q CT
Sbjct: 111 PDVVLLN---NNDGNFYVALDISVVVSSDGSVRWQPPGIYRSSCSIQVTYFPFDWQNCTM 167
Query: 506 KFGSRMHXSDEM 541
F S + S E+
Sbjct: 168 VFSSYSYDSSEV 179
>BC006314-1|AAH06314.1| 269|Homo sapiens CHRNA1 protein protein.
Length = 269
Score = 62.5 bits (145), Expect = 2e-09
Identities = 44/167 (26%), Positives = 77/167 (46%), Gaps = 10/167 (5%)
Frame = +2
Query: 47 PFLLTCAIASAAECENATSLSLMIDSLLATYDRDSPP--DSKIVVNLTLHLRHA---NIR 211
P LL ++ SA + + ++ L Y P D + VV +T+ L+ N+
Sbjct: 5 PLLLLFSLCSAGLVLGSEHETRLVAKLFKDYSSVVRPVEDHRQVVEVTVGLQLIQLINVD 64
Query: 212 ESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYA 388
E V L+ W+D L WN ++G + + SE++WRPD+VL N A GD+A
Sbjct: 65 EVNQIVTTNVRLKQQWVDYNLKWNPDDYGGVKKIHIPSEKIWRPDLVLYNNA---DGDFA 121
Query: 389 L----RARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 517
+ + + G ++W + + + ++P D Q C+ K G+
Sbjct: 122 IVKFTKVLLQYTGHITWTPPAIFKSYCEIIVTHFPFDEQNCSMKLGT 168
>AC018890-1|AAY14687.1| 457|Homo sapiens unknown protein.
Length = 457
Score = 62.5 bits (145), Expect = 2e-09
Identities = 44/167 (26%), Positives = 77/167 (46%), Gaps = 10/167 (5%)
Frame = +2
Query: 47 PFLLTCAIASAAECENATSLSLMIDSLLATYDRDSPP--DSKIVVNLTLHLRHA---NIR 211
P LL ++ SA + + ++ L Y P D + VV +T+ L+ N+
Sbjct: 5 PLLLLFSLCSAGLVLGSEHETRLVAKLFKDYSSVVRPVEDHRQVVEVTVGLQLIQLINVD 64
Query: 212 ESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYA 388
E V L+ W+D L WN ++G + + SE++WRPD+VL N A GD+A
Sbjct: 65 EVNQIVTTNVRLKQQWVDYNLKWNPDDYGGVKKIHIPSEKIWRPDLVLYNNA---DGDFA 121
Query: 389 L----RARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 517
+ + + G ++W + + + ++P D Q C+ K G+
Sbjct: 122 IVKFTKVLLQYTGHITWTPPAIFKSYCEIIVTHFPFDEQNCSMKLGT 168
>Y08419-1|CAA69696.1| 468|Homo sapiens nicotinic acetylcholine
receptor alpha5 subunit precursor protein.
Length = 468
Score = 62.1 bits (144), Expect = 2e-09
Identities = 36/141 (25%), Positives = 66/141 (46%), Gaps = 6/141 (4%)
Frame = +2
Query: 113 MIDSLLATYDRDSPP----DSKIVVNLTLHLRH-ANIRESESTVRIQADLQMNWIDKRLS 277
++ L Y+R P + KI + L + ++ E + L+ WID +L
Sbjct: 50 LLKDLFQDYERWVRPVEHLNDKIKIKFGLAISQLVDVDEKNQLMTTNVWLKQEWIDVKLR 109
Query: 278 WNAGEWG-CSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVSWIKRLDISTP 454
WN ++G V S+ +W PD+VL + A + + + NG+V+W + +
Sbjct: 110 WNPDDYGGIKVIRVPSDSVWTPDIVLFDNADGRFEGTSTKTVIRYNGTVTWTPPANYKSS 169
Query: 455 ISMQLDNWPNDMQTCTFKFGS 517
++ + +P D+Q C+ KFGS
Sbjct: 170 CTIDVTFFPFDLQNCSMKFGS 190
>X53559-1|CAA37625.1| 474|Homo sapiens neuronal nicotinic
acetylcholine receptor alpha-3merase protein.
Length = 474
Score = 62.1 bits (144), Expect = 2e-09
Identities = 30/93 (32%), Positives = 50/93 (53%), Gaps = 2/93 (2%)
Frame = +2
Query: 245 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 418
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 56 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 115
Query: 419 VSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 517
V+WI + + + +P D Q CT KFGS
Sbjct: 116 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGS 148
>U62434-1|AAB40112.1| 468|Homo sapiens nicotinic acetylcholine
receptor alpha5 subunit precursor protein.
Length = 468
Score = 62.1 bits (144), Expect = 2e-09
Identities = 36/141 (25%), Positives = 66/141 (46%), Gaps = 6/141 (4%)
Frame = +2
Query: 113 MIDSLLATYDRDSPP----DSKIVVNLTLHLRH-ANIRESESTVRIQADLQMNWIDKRLS 277
++ L Y+R P + KI + L + ++ E + L+ WID +L
Sbjct: 50 LLKDLFQDYERWVRPVEHLNDKIKIKFGLAISQLVDVDEKNQLMTTNVWLKQEWIDVKLR 109
Query: 278 WNAGEWG-CSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVSWIKRLDISTP 454
WN ++G V S+ +W PD+VL + A + + + NG+V+W + +
Sbjct: 110 WNPDDYGGIKVIRVPSDSVWTPDIVLFDNADGRFEGTSTKTVIRYNGTVTWTPPANYKSS 169
Query: 455 ISMQLDNWPNDMQTCTFKFGS 517
++ + +P D+Q C+ KFGS
Sbjct: 170 CTIDVTFFPFDLQNCSMKFGS 190
>BC033639-1|AAH33639.1| 468|Homo sapiens cholinergic receptor,
nicotinic, alpha 5 protein.
Length = 468
Score = 62.1 bits (144), Expect = 2e-09
Identities = 36/141 (25%), Positives = 66/141 (46%), Gaps = 6/141 (4%)
Frame = +2
Query: 113 MIDSLLATYDRDSPP----DSKIVVNLTLHLRH-ANIRESESTVRIQADLQMNWIDKRLS 277
++ L Y+R P + KI + L + ++ E + L+ WID +L
Sbjct: 50 LLKDLFQDYERWVRPVEHLNDKIKIKFGLAISQLVDVDEKNQLMTTNVWLKQEWIDVKLR 109
Query: 278 WNAGEWG-CSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVSWIKRLDISTP 454
WN ++G V S+ +W PD+VL + A + + + NG+V+W + +
Sbjct: 110 WNPDDYGGIKVIRVPSDSVWTPDIVLFDNADGRFEGTSTKTVIRYNGTVTWTPPANYKSS 169
Query: 455 ISMQLDNWPNDMQTCTFKFGS 517
++ + +P D+Q C+ KFGS
Sbjct: 170 CTIDVTFFPFDLQNCSMKFGS 190
>AJ306481-1|CAC34820.1| 468|Homo sapiens neuronal nicotinic
acetylcholine receptor alpha-5subunit protein.
Length = 468
Score = 62.1 bits (144), Expect = 2e-09
Identities = 36/141 (25%), Positives = 66/141 (46%), Gaps = 6/141 (4%)
Frame = +2
Query: 113 MIDSLLATYDRDSPP----DSKIVVNLTLHLRH-ANIRESESTVRIQADLQMNWIDKRLS 277
++ L Y+R P + KI + L + ++ E + L+ WID +L
Sbjct: 50 LLKDLFQDYERWVRPVEHLNDKIKIKFGLAISQLVDVDEKNQLMTTNVWLKQEWIDVKLR 109
Query: 278 WNAGEWG-CSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVSWIKRLDISTP 454
WN ++G V S+ +W PD+VL + A + + + NG+V+W + +
Sbjct: 110 WNPDDYGGIKVIRVPSDSVWTPDIVLFDNADGRFEGTSTKTVIRYNGTVTWTPPANYKSS 169
Query: 455 ISMQLDNWPNDMQTCTFKFGS 517
++ + +P D+Q C+ KFGS
Sbjct: 170 CTIDVTFFPFDLQNCSMKFGS 190
>Y16282-1|CAA76155.1| 494|Homo sapiens nicotinic acetylcholine
receptor alpha6 subunit precursor protein.
Length = 494
Score = 61.7 bits (143), Expect = 3e-09
Identities = 41/162 (25%), Positives = 74/162 (45%), Gaps = 10/162 (6%)
Frame = +2
Query: 86 CENATSLSLMIDSLLATYDRDSPPDSKIVVNLTLHL-----RHANIRESESTVRIQADLQ 250
C + + L + Y++ P + +T+H + AN+ E + L+
Sbjct: 28 CVGCATEERLFHKLFSHYNQFIRPVENVSDPVTVHFEVAITQLANVDEVNQIMETNLWLR 87
Query: 251 MNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNG 415
W D +L W+ E+ G T V ++++W+PD+VL N A GD+ + +A + NG
Sbjct: 88 HIWNDYKLRWDPMEYDGIETLRVPADKIWKPDIVLYNNAV---GDFQVEGKTKALLKYNG 144
Query: 416 SVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXSDEM 541
++W + M + +P D Q C+ KFGS + E+
Sbjct: 145 MITWTPPAIFKSSCPMDITFFPFDHQNCSLKFGSWTYDKAEI 186
>U62435-1|AAB40113.1| 494|Homo sapiens nicotinic acetylcholine
receptor alpha6 subunit precursor protein.
Length = 494
Score = 61.7 bits (143), Expect = 3e-09
Identities = 41/162 (25%), Positives = 74/162 (45%), Gaps = 10/162 (6%)
Frame = +2
Query: 86 CENATSLSLMIDSLLATYDRDSPPDSKIVVNLTLHL-----RHANIRESESTVRIQADLQ 250
C + + L + Y++ P + +T+H + AN+ E + L+
Sbjct: 28 CVGCATEERLFHKLFSHYNQFIRPVENVSDPVTVHFEVAITQLANVDEVNQIMETNLWLR 87
Query: 251 MNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNG 415
W D +L W+ E+ G T V ++++W+PD+VL N A GD+ + +A + NG
Sbjct: 88 HIWNDYKLRWDPMEYDGIETLRVPADKIWKPDIVLYNNAV---GDFQVEGKTKALLKYNG 144
Query: 416 SVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXSDEM 541
++W + M + +P D Q C+ KFGS + E+
Sbjct: 145 MITWTPPAIFKSSCPMDITFFPFDHQNCSLKFGSWTYDKAEI 186
>BC014456-1|AAH14456.1| 494|Homo sapiens cholinergic receptor,
nicotinic, alpha 6 protein.
Length = 494
Score = 61.7 bits (143), Expect = 3e-09
Identities = 41/162 (25%), Positives = 74/162 (45%), Gaps = 10/162 (6%)
Frame = +2
Query: 86 CENATSLSLMIDSLLATYDRDSPPDSKIVVNLTLHL-----RHANIRESESTVRIQADLQ 250
C + + L + Y++ P + +T+H + AN+ E + L+
Sbjct: 28 CVGCATEERLFHKLFSHYNQFIRPVENVSDPVTVHFEVAITQLANVDEVNQIMETNLWLR 87
Query: 251 MNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNG 415
W D +L W+ E+ G T V ++++W+PD+VL N A GD+ + +A + NG
Sbjct: 88 HIWNDYKLRWDPMEYDGIETLRVPADKIWKPDIVLYNNAV---GDFQVEGKTKALLKYNG 144
Query: 416 SVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXSDEM 541
++W + M + +P D Q C+ KFGS + E+
Sbjct: 145 MITWTPPAIFKSSCPMDITFFPFDHQNCSLKFGSWTYDKAEI 186
>AB079251-1|BAC06855.1| 494|Homo sapiens Nicotinic acetylcholine
receptor alpha 6 protein.
Length = 494
Score = 61.7 bits (143), Expect = 3e-09
Identities = 41/162 (25%), Positives = 74/162 (45%), Gaps = 10/162 (6%)
Frame = +2
Query: 86 CENATSLSLMIDSLLATYDRDSPPDSKIVVNLTLHL-----RHANIRESESTVRIQADLQ 250
C + + L + Y++ P + +T+H + AN+ E + L+
Sbjct: 28 CVGCATEERLFHKLFSHYNQFIRPVENVSDPVTVHFEVAITQLANVDEVNQIMETNLWLR 87
Query: 251 MNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNG 415
W D +L W+ E+ G T V ++++W+PD+VL N A GD+ + +A + NG
Sbjct: 88 HIWNDYKLRWDPMEYDGIETLRVPADKIWKPDIVLYNNAV---GDFQVEGKTKALLKYNG 144
Query: 416 SVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXSDEM 541
++W + M + +P D Q C+ KFGS + E+
Sbjct: 145 MITWTPPAIFKSSCPMDITFFPFDHQNCSLKFGSWTYDKAEI 186
>M86383-1|AAC84176.1| 502|Homo sapiens nicotinic acetylcholine
receptor alpha 3 subunit precursor protein.
Length = 502
Score = 61.3 bits (142), Expect = 4e-09
Identities = 44/167 (26%), Positives = 78/167 (46%), Gaps = 6/167 (3%)
Frame = +2
Query: 35 IILLPFLLTCAIASAAECENATSLSLMIDSLLATYDRDSPPDSKIVVNLTLHLRH-ANIR 211
++LL LL A AS AE L + ++ S P ++++ + + +
Sbjct: 16 LLLLLSLLPVARASEAEHRLFERLFEDYNEIIRPVANVSDP---VIIHFEVSMSQLVKVD 72
Query: 212 ESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYA 388
E + L+ W D +L WN +G + ++ V ++++W+PD+VL N A GD+
Sbjct: 73 EVNQIMETNLWLKQIWNDYKLKWNPSGYGGAEFMRVPAQKIWKPDIVLYNNAV---GDFQ 129
Query: 389 L----RARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 517
+ +A + G V+WI + + + +P D Q CT KFGS
Sbjct: 130 VTTKTKALLKYTGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGS 176
>M83712-1|AAA58357.1| 468|Homo sapiens nicotinic receptor alpha 5
subunit protein.
Length = 468
Score = 60.9 bits (141), Expect = 5e-09
Identities = 36/141 (25%), Positives = 65/141 (46%), Gaps = 6/141 (4%)
Frame = +2
Query: 113 MIDSLLATYDRDSPP----DSKIVVNLTLHLRH-ANIRESESTVRIQADLQMNWIDKRLS 277
++ L Y+R P + KI + L + ++ E + L+ WID +L
Sbjct: 50 LLKDLFQDYERWVRPVEHLNDKIKIKFGLAISQLVDVDEKNQLMTTNVWLKQEWIDVKLR 109
Query: 278 WNAGEWG-CSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVSWIKRLDISTP 454
WN ++G V S+ W PD+VL + A + + + NG+V+W + +
Sbjct: 110 WNPDDYGGIKVIRVPSDSSWTPDIVLFDNADGRFEGTSTKTVIRYNGTVTWTPPANYKSS 169
Query: 455 ISMQLDNWPNDMQTCTFKFGS 517
++ + +P D+Q C+ KFGS
Sbjct: 170 CTIDVTFFPFDLQNCSMKFGS 190
>X01715-1|CAA25861.1| 520|Homo sapiens acetylcholine receptor gamma
chain precursor protein.
Length = 520
Score = 60.5 bits (140), Expect = 7e-09
Identities = 49/177 (27%), Positives = 81/177 (45%), Gaps = 8/177 (4%)
Frame = +2
Query: 35 IILLPFLLTCAIASAAECENATSLSLMIDSLLATYDRDSPPDSKI--VVNLTLHLRHANI 208
++LL L C + N L+ D L+ YD + P + VVN++L L N+
Sbjct: 8 LLLLLLLAVCLGGTQRNLRNQEE-RLLAD-LMQNYDPNLRPAERDSDVVNVSLKLTLTNL 65
Query: 209 ---RESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTA 376
E E + ++M W D RL W+ ++ G V S +WRPD+VL N
Sbjct: 66 ISLNEREEALTTNVWIEMQWCDYRLRWDPRDYEGLWVLRVPSTMVWRPDIVLENNVDGVF 125
Query: 377 GDYALRARV--SNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXSDEM 541
+ AL V S +G + W+ + S+ + +P D Q C+ F S+ + ++E+
Sbjct: 126 -EVALYCNVLVSPDGCIYWLPPAIFRSACSISVTYFPFDWQNCSLIFQSQTYSTNEI 181
>AC092165-3|AAY24103.1| 520|Homo sapiens unknown protein.
Length = 520
Score = 60.5 bits (140), Expect = 7e-09
Identities = 49/177 (27%), Positives = 81/177 (45%), Gaps = 8/177 (4%)
Frame = +2
Query: 35 IILLPFLLTCAIASAAECENATSLSLMIDSLLATYDRDSPPDSKI--VVNLTLHLRHANI 208
++LL L C + N L+ D L+ YD + P + VVN++L L N+
Sbjct: 8 LLLLLLLAVCLGGTQRNLRNQEE-RLLAD-LMQNYDPNLRPAERDSDVVNVSLKLTLTNL 65
Query: 209 ---RESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTA 376
E E + ++M W D RL W+ ++ G V S +WRPD+VL N
Sbjct: 66 ISLNEREEALTTNVWIEMQWCDYRLRWDPRDYEGLWVLRVPSTMVWRPDIVLENNVDGVF 125
Query: 377 GDYALRARV--SNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXSDEM 541
+ AL V S +G + W+ + S+ + +P D Q C+ F S+ + ++E+
Sbjct: 126 -EVALYCNVLVSPDGCIYWLPPAIFRSACSISVTYFPFDWQNCSLIFQSQTYSTNEI 181
>X66403-1|CAA47030.1| 493|Homo sapiens acetylcholine receptor
epsilon subunit CHRNE protein.
Length = 493
Score = 60.1 bits (139), Expect = 1e-08
Identities = 35/134 (26%), Positives = 69/134 (51%), Gaps = 3/134 (2%)
Frame = +2
Query: 155 PDSKIVVNLTLHLRHA-NIRESESTVRIQADLQMNWIDKRLSWNAGEWG-CSTWLVSSER 328
P+ + ++L + L + ++ E E T+ + ++W D RL+++ ++G T V SE
Sbjct: 45 PEDTVTISLKVTLTNLISLNEKEETLTTSVWIGIDWQDYRLNYSKDDFGGIETLRVPSEL 104
Query: 329 LWRPDVVLLNAAATTAG-DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTF 505
+W P++VL N G Y V GSV+W+ + ++++ +P D Q C+
Sbjct: 105 VWLPEIVLENNIDGQFGVAYDANVLVYEGGSVTWLPPAIYRSVCAVEVTYFPFDWQNCSL 164
Query: 506 KFGSRMHXSDEMXF 547
F S+ + ++E+ F
Sbjct: 165 IFRSQTYNAEEVEF 178
>AF105999-1|AAD24503.1| 493|Homo sapiens acetylcholine receptor
epsilon subunit protein.
Length = 493
Score = 60.1 bits (139), Expect = 1e-08
Identities = 35/134 (26%), Positives = 69/134 (51%), Gaps = 3/134 (2%)
Frame = +2
Query: 155 PDSKIVVNLTLHLRHA-NIRESESTVRIQADLQMNWIDKRLSWNAGEWG-CSTWLVSSER 328
P+ + ++L + L + ++ E E T+ + ++W D RL+++ ++G T V SE
Sbjct: 45 PEDTVTISLKVTLTNLISLNEKEETLTTSVWIGIDWQDYRLNYSKDDFGGIETLRVPSEL 104
Query: 329 LWRPDVVLLNAAATTAG-DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTF 505
+W P++VL N G Y V GSV+W+ + ++++ +P D Q C+
Sbjct: 105 VWLPEIVLENNIDGQFGVAYDANVLVYEGGSVTWLPPAIYRSVCAVEVTYFPFDWQNCSL 164
Query: 506 KFGSRMHXSDEMXF 547
F S+ + ++E+ F
Sbjct: 165 IFRSQTYNAEEVEF 178
>Y08421-1|CAA69698.1| 627|Homo sapiens nicotinic acetylcholine
receptor alpha4 subunit precursor protein.
Length = 627
Score = 59.7 bits (138), Expect = 1e-08
Identities = 48/170 (28%), Positives = 83/170 (48%), Gaps = 11/170 (6%)
Frame = +2
Query: 41 LLPFLLTCAIASAAECEN-ATSLSLMIDSLLATYDRDSPPDSKI--VVNLTLHLRHA--- 202
LL L T + +++ E A + ++ L + Y++ S P + I VV + L A
Sbjct: 15 LLLLLGTGLLRASSHVETRAHAEERLLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLI 74
Query: 203 NIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAG 379
++ E + ++ W D +L W+ ++ T + + SE +WRPD+VL N A G
Sbjct: 75 DVDEKNQMMTTNVWVKQEWHDYKLRWDPADYENVTSIRIPSELIWRPDIVLYNNAD---G 131
Query: 380 DYAL----RARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 517
D+A+ +A + ++G V W + S+ + +P D Q CT KFGS
Sbjct: 132 DFAVTHLTKAHLFHDGRVQWTPPAIYKSSCSIDVTFFPFDQQNCTMKFGS 181
>X89741-1|CAA61893.1| 627|Homo sapiens neuronal acetylcholine
receptor alpha-4 subunit protein.
Length = 627
Score = 59.7 bits (138), Expect = 1e-08
Identities = 48/170 (28%), Positives = 83/170 (48%), Gaps = 11/170 (6%)
Frame = +2
Query: 41 LLPFLLTCAIASAAECEN-ATSLSLMIDSLLATYDRDSPPDSKI--VVNLTLHLRHA--- 202
LL L T + +++ E A + ++ L + Y++ S P + I VV + L A
Sbjct: 15 LLLLLGTGLLRASSHVETRAHAEERLLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLI 74
Query: 203 NIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAG 379
++ E + ++ W D +L W+ ++ T + + SE +WRPD+VL N A G
Sbjct: 75 DVDEKNQMMTTNVWVKQEWHDYKLRWDPADYENVTSIRIPSELIWRPDIVLYNNAD---G 131
Query: 380 DYAL----RARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 517
D+A+ +A + ++G V W + S+ + +P D Q CT KFGS
Sbjct: 132 DFAVTHLTKAHLFHDGRVQWTPPAIYKSSCSIDVTFFPFDQQNCTMKFGS 181
>U62433-1|AAB40111.1| 627|Homo sapiens nicotinic acetylcholine
receptor alpha4 subunit precursor protein.
Length = 627
Score = 59.7 bits (138), Expect = 1e-08
Identities = 48/170 (28%), Positives = 83/170 (48%), Gaps = 11/170 (6%)
Frame = +2
Query: 41 LLPFLLTCAIASAAECEN-ATSLSLMIDSLLATYDRDSPPDSKI--VVNLTLHLRHA--- 202
LL L T + +++ E A + ++ L + Y++ S P + I VV + L A
Sbjct: 15 LLLLLGTGLLRASSHVETRAHAEERLLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLI 74
Query: 203 NIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAG 379
++ E + ++ W D +L W+ ++ T + + SE +WRPD+VL N A G
Sbjct: 75 DVDEKNQMMTTNVWVKQEWHDYKLRWDPADYENVTSIRIPSELIWRPDIVLYNNAD---G 131
Query: 380 DYAL----RARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 517
D+A+ +A + ++G V W + S+ + +P D Q CT KFGS
Sbjct: 132 DFAVTHLTKAHLFHDGRVQWTPPAIYKSSCSIDVTFFPFDQQNCTMKFGS 181
>L35901-1|AAA64743.1| 627|Homo sapiens nicotinic acetylcholine
receptor alpha 4 subunit protein.
Length = 627
Score = 59.7 bits (138), Expect = 1e-08
Identities = 48/170 (28%), Positives = 83/170 (48%), Gaps = 11/170 (6%)
Frame = +2
Query: 41 LLPFLLTCAIASAAECEN-ATSLSLMIDSLLATYDRDSPPDSKI--VVNLTLHLRHA--- 202
LL L T + +++ E A + ++ L + Y++ S P + I VV + L A
Sbjct: 15 LLLLLGTGLLRASSHVETRAHAEERLLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLI 74
Query: 203 NIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAG 379
++ E + ++ W D +L W+ ++ T + + SE +WRPD+VL N A G
Sbjct: 75 DVDEKNQMMTTNVWVKQEWHDYKLRWDPADYENVTSIRIPSELIWRPDIVLYNNAD---G 131
Query: 380 DYAL----RARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 517
D+A+ +A + ++G V W + S+ + +P D Q CT KFGS
Sbjct: 132 DFAVTHLTKAHLFHDGRVQWTPPAIYKSSCSIDVTFFPFDQQNCTMKFGS 181
>DQ093071-1|AAY88737.1| 627|Homo sapiens cholinergic receptor,
nicotinic, alpha polypeptide 4 protein.
Length = 627
Score = 59.7 bits (138), Expect = 1e-08
Identities = 48/170 (28%), Positives = 83/170 (48%), Gaps = 11/170 (6%)
Frame = +2
Query: 41 LLPFLLTCAIASAAECEN-ATSLSLMIDSLLATYDRDSPPDSKI--VVNLTLHLRHA--- 202
LL L T + +++ E A + ++ L + Y++ S P + I VV + L A
Sbjct: 15 LLLLLGTGLLRASSHVETRAHAEERLLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLI 74
Query: 203 NIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAG 379
++ E + ++ W D +L W+ ++ T + + SE +WRPD+VL N A G
Sbjct: 75 DVDEKNQMMTTNVWVKQEWHDYKLRWDPADYENVTSIRIPSELIWRPDIVLYNNAD---G 131
Query: 380 DYAL----RARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 517
D+A+ +A + ++G V W + S+ + +P D Q CT KFGS
Sbjct: 132 DFAVTHLTKAHLFHDGRVQWTPPAIYKSSCSIDVTFFPFDQQNCTMKFGS 181
>BC096290-1|AAH96290.1| 627|Homo sapiens cholinergic receptor,
nicotinic, alpha 4 protein.
Length = 627
Score = 59.7 bits (138), Expect = 1e-08
Identities = 48/170 (28%), Positives = 83/170 (48%), Gaps = 11/170 (6%)
Frame = +2
Query: 41 LLPFLLTCAIASAAECEN-ATSLSLMIDSLLATYDRDSPPDSKI--VVNLTLHLRHA--- 202
LL L T + +++ E A + ++ L + Y++ S P + I VV + L A
Sbjct: 15 LLLLLGTGLLRASSHVETRAHAEERLLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLI 74
Query: 203 NIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAG 379
++ E + ++ W D +L W+ ++ T + + SE +WRPD+VL N A G
Sbjct: 75 DVDEKNQMMTTNVWVKQEWHDYKLRWDPADYENVTSIRIPSELIWRPDIVLYNNAD---G 131
Query: 380 DYAL----RARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 517
D+A+ +A + ++G V W + S+ + +P D Q CT KFGS
Sbjct: 132 DFAVTHLTKAHLFHDGRVQWTPPAIYKSSCSIDVTFFPFDQQNCTMKFGS 181
>AJ001935-1|CAA05108.1| 504|Homo sapiens CHRNB2 protein.
Length = 504
Score = 59.7 bits (138), Expect = 1e-08
Identities = 53/199 (26%), Positives = 83/199 (41%), Gaps = 8/199 (4%)
Frame = +2
Query: 38 ILLPF--LLTCAIASAAECENATSLSLMIDSLLATYDRDSPPDSKIV-VNLTLHLRHA-N 205
+LL F L C+ A+ E L+ S R + S++V V L + L +
Sbjct: 10 LLLGFGLLRLCSGVWGADTEERLVEHLLDPSRYNKLIRPATNGSELVTVQLMVSLAQLIS 69
Query: 206 IRESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAG 379
+ E E + L W D RL+W E+ + S+ +W PDVVL N A
Sbjct: 70 VHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLPDVVLYNNADGMYEV 129
Query: 380 DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXSDE--MXFRD 553
+ A VS +GS+ W+ + +++ ++P D Q CT KF S + E + +
Sbjct: 130 SFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRSWTYDRTEIDLVLKS 189
Query: 554 *XKEYTXCPXPGXWDVTAL 610
G WD+ AL
Sbjct: 190 EVASLDDFTPSGEWDIVAL 208
>Y08415-1|CAA69692.1| 502|Homo sapiens nicotinic acetylcholine
receptor beta2 subunit precursor protein.
Length = 502
Score = 59.3 bits (137), Expect = 2e-08
Identities = 41/153 (26%), Positives = 65/153 (42%), Gaps = 5/153 (3%)
Frame = +2
Query: 167 IVVNLTLHLRHA-NIRESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 340
+ V L + L ++ E E + L W D RL+W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 341 DVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 517
DVVL N A + A VS +GS+ W+ + +++ ++P D Q CT KF S
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRS 175
Query: 518 RMHXSDE--MXFRD*XKEYTXCPXPGXWDVTAL 610
+ E + + G WD+ AL
Sbjct: 176 WTYDRTEIDLVLKSEVASLDDFTPSGEWDIVAL 208
>X87629-1|CAA60959.1| 602|Homo sapiens nicotinic acetylcholine
receptor protein.
Length = 602
Score = 59.3 bits (137), Expect = 2e-08
Identities = 42/145 (28%), Positives = 72/145 (49%), Gaps = 10/145 (6%)
Frame = +2
Query: 113 MIDSLLATYDRDSPPDSKI--VVNLTLHLRHA---NIRESESTVRIQADLQMNWIDKRLS 277
++ L + Y++ S P + I VV + L A ++ E + ++ W D +L
Sbjct: 15 LLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLR 74
Query: 278 WNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNGSVSWIKRLD 442
W+ ++ T + + SE +WRPD+VL N A GD+A+ +A + ++G V W
Sbjct: 75 WDPADYENVTSIRIPSELIWRPDIVLYNNAD---GDFAVTHLTKAHLFHDGRVQWTPPAI 131
Query: 443 ISTPISMQLDNWPNDMQTCTFKFGS 517
+ S+ + +P D Q CT KFGS
Sbjct: 132 YKSSCSIDVTFFPFDQQNCTMKFGS 156
>X53179-1|CAA37320.1| 502|Homo sapiens precursor peptide (AA -25 to
477) protein.
Length = 502
Score = 59.3 bits (137), Expect = 2e-08
Identities = 41/153 (26%), Positives = 65/153 (42%), Gaps = 5/153 (3%)
Frame = +2
Query: 167 IVVNLTLHLRHA-NIRESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 340
+ V L + L ++ E E + L W D RL+W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 341 DVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 517
DVVL N A + A VS +GS+ W+ + +++ ++P D Q CT KF S
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRS 175
Query: 518 RMHXSDE--MXFRD*XKEYTXCPXPGXWDVTAL 610
+ E + + G WD+ AL
Sbjct: 176 WTYDRTEIDLVLKSEVASLDDFTPSGEWDIVAL 208
>U62437-1|AAB40115.1| 502|Homo sapiens nicotinic acetylcholine
receptor beta2 subunit precursor protein.
Length = 502
Score = 59.3 bits (137), Expect = 2e-08
Identities = 41/153 (26%), Positives = 65/153 (42%), Gaps = 5/153 (3%)
Frame = +2
Query: 167 IVVNLTLHLRHA-NIRESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 340
+ V L + L ++ E E + L W D RL+W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 341 DVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 517
DVVL N A + A VS +GS+ W+ + +++ ++P D Q CT KF S
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRS 175
Query: 518 RMHXSDE--MXFRD*XKEYTXCPXPGXWDVTAL 610
+ E + + G WD+ AL
Sbjct: 176 WTYDRTEIDLVLKSEVASLDDFTPSGEWDIVAL 208
>BC075041-1|AAH75041.1| 502|Homo sapiens cholinergic receptor,
nicotinic, beta 2 (neuronal) protein.
Length = 502
Score = 59.3 bits (137), Expect = 2e-08
Identities = 41/153 (26%), Positives = 65/153 (42%), Gaps = 5/153 (3%)
Frame = +2
Query: 167 IVVNLTLHLRHA-NIRESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 340
+ V L + L ++ E E + L W D RL+W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 341 DVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 517
DVVL N A + A VS +GS+ W+ + +++ ++P D Q CT KF S
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRS 175
Query: 518 RMHXSDE--MXFRD*XKEYTXCPXPGXWDVTAL 610
+ E + + G WD+ AL
Sbjct: 176 WTYDRTEIDLVLKSEVASLDDFTPSGEWDIVAL 208
>BC075040-1|AAH75040.1| 502|Homo sapiens cholinergic receptor,
nicotinic, beta 2 (neuronal) protein.
Length = 502
Score = 59.3 bits (137), Expect = 2e-08
Identities = 41/153 (26%), Positives = 65/153 (42%), Gaps = 5/153 (3%)
Frame = +2
Query: 167 IVVNLTLHLRHA-NIRESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 340
+ V L + L ++ E E + L W D RL+W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 341 DVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 517
DVVL N A + A VS +GS+ W+ + +++ ++P D Q CT KF S
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRS 175
Query: 518 RMHXSDE--MXFRD*XKEYTXCPXPGXWDVTAL 610
+ E + + G WD+ AL
Sbjct: 176 WTYDRTEIDLVLKSEVASLDDFTPSGEWDIVAL 208
>AL592078-3|CAI16184.1| 502|Homo sapiens cholinergic receptor,
nicotinic, beta 2 (neuronal) protein.
Length = 502
Score = 59.3 bits (137), Expect = 2e-08
Identities = 41/153 (26%), Positives = 65/153 (42%), Gaps = 5/153 (3%)
Frame = +2
Query: 167 IVVNLTLHLRHA-NIRESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 340
+ V L + L ++ E E + L W D RL+W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 341 DVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 517
DVVL N A + A VS +GS+ W+ + +++ ++P D Q CT KF S
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRS 175
Query: 518 RMHXSDE--MXFRD*XKEYTXCPXPGXWDVTAL 610
+ E + + G WD+ AL
Sbjct: 176 WTYDRTEIDLVLKSEVASLDDFTPSGEWDIVAL 208
>AF077186-1|AAD45422.1| 502|Homo sapiens neuronal nicotinic
acetylcholine receptor beta 2 protein.
Length = 502
Score = 59.3 bits (137), Expect = 2e-08
Identities = 41/153 (26%), Positives = 65/153 (42%), Gaps = 5/153 (3%)
Frame = +2
Query: 167 IVVNLTLHLRHA-NIRESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 340
+ V L + L ++ E E + L W D RL+W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 341 DVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 517
DVVL N A + A VS +GS+ W+ + +++ ++P D Q CT KF S
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRS 175
Query: 518 RMHXSDE--MXFRD*XKEYTXCPXPGXWDVTAL 610
+ E + + G WD+ AL
Sbjct: 176 WTYDRTEIDLVLKSEVASLDDFTPSGEWDIVAL 208
>X55019-1|CAA38759.1| 517|Homo sapiens acetylcholine receptor delta
subunit protein.
Length = 517
Score = 56.8 bits (131), Expect = 9e-08
Identities = 35/131 (26%), Positives = 62/131 (47%), Gaps = 3/131 (2%)
Frame = +2
Query: 158 DSKIVVNLTLHLRHA-NIRESESTVRIQADLQMNWIDKRLSWNAGEWG-CSTWLVSSERL 331
+ + V L L L + +++E E T+ ++ W D RL WNA E+G S + + +
Sbjct: 49 EESVDVALALTLSNLISLKEVEETLTTNVWIEHGWTDNRLKWNAEEFGNISVLRLPPDMV 108
Query: 332 WRPDVVL-LNAAATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFK 508
W P++VL N + Y+ V + G V W+ + + + +P D Q C+ K
Sbjct: 109 WLPEIVLENNNDGSFQISYSCNVLVYHYGFVYWLPPAIFRSSCPISVTYFPFDWQNCSLK 168
Query: 509 FGSRMHXSDEM 541
F S + + E+
Sbjct: 169 FSSLKYTAKEI 179
>BC093925-1|AAH93925.1| 517|Homo sapiens cholinergic receptor,
nicotinic, delta protein.
Length = 517
Score = 56.8 bits (131), Expect = 9e-08
Identities = 35/131 (26%), Positives = 62/131 (47%), Gaps = 3/131 (2%)
Frame = +2
Query: 158 DSKIVVNLTLHLRHA-NIRESESTVRIQADLQMNWIDKRLSWNAGEWG-CSTWLVSSERL 331
+ + V L L L + +++E E T+ ++ W D RL WNA E+G S + + +
Sbjct: 49 EESVDVALALTLSNLISLKEVEETLTTNVWIEHGWTDNRLKWNAEEFGNISVLRLPPDMV 108
Query: 332 WRPDVVL-LNAAATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFK 508
W P++VL N + Y+ V + G V W+ + + + +P D Q C+ K
Sbjct: 109 WLPEIVLENNNDGSFQISYSCNVLVYHYGFVYWLPPAIFRSSCPISVTYFPFDWQNCSLK 168
Query: 509 FGSRMHXSDEM 541
F S + + E+
Sbjct: 169 FSSLKYTAKEI 179
>BC093923-1|AAH93923.1| 517|Homo sapiens cholinergic receptor,
nicotinic, delta protein.
Length = 517
Score = 56.8 bits (131), Expect = 9e-08
Identities = 35/131 (26%), Positives = 62/131 (47%), Gaps = 3/131 (2%)
Frame = +2
Query: 158 DSKIVVNLTLHLRHA-NIRESESTVRIQADLQMNWIDKRLSWNAGEWG-CSTWLVSSERL 331
+ + V L L L + +++E E T+ ++ W D RL WNA E+G S + + +
Sbjct: 49 EESVDVALALTLSNLISLKEVEETLTTNVWIEHGWTDNRLKWNAEEFGNISVLRLPPDMV 108
Query: 332 WRPDVVL-LNAAATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFK 508
W P++VL N + Y+ V + G V W+ + + + +P D Q C+ K
Sbjct: 109 WLPEIVLENNNDGSFQISYSCNVLVYHYGFVYWLPPAIFRSSCPISVTYFPFDWQNCSLK 168
Query: 509 FGSRMHXSDEM 541
F S + + E+
Sbjct: 169 FSSLKYTAKEI 179
>AJ295237-1|CAC16144.1| 450|Homo sapiens neuronal nicotinic
acetylcholine receptor subunit4 protein.
Length = 450
Score = 56.8 bits (131), Expect = 9e-08
Identities = 48/178 (26%), Positives = 75/178 (42%), Gaps = 7/178 (3%)
Frame = +2
Query: 38 ILLPFLLTCAIASAAECENATSLSLMIDSLLATYDRDSPP--DSKIVVNLTLHLRHANI- 208
+LL FLL A E +L L D L A Y P D+ +N+TL + + I
Sbjct: 12 LLLLFLLPAECLGA---EGRLALKLFRD-LFANYTSALRPVADTDQTLNVTLEVTLSQII 67
Query: 209 --RESESTVRIQADLQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLLNAA-ATTA 376
E + + ++ W D L W+ +G + S +WRPD+VL N A A
Sbjct: 68 DMDERNQVLTLYLWIRQEWTDAYLRWDPNAYGGLDAIRIPSSLVWRPDIVLYNKADAQPP 127
Query: 377 GDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXSDEMXFR 550
G + + ++G+V W + + + +P D Q C FGS H ++ R
Sbjct: 128 GSASTNVVLRHDGAVRWDAPAITRSSCRVDVAAFPFDAQHCGLTFGSWTHGGHQLDVR 185
>AJ278118-1|CAC20435.1| 450|Homo sapiens neuronal nicotinic
acetylcholine alpha10 subunit protein.
Length = 450
Score = 56.8 bits (131), Expect = 9e-08
Identities = 48/178 (26%), Positives = 75/178 (42%), Gaps = 7/178 (3%)
Frame = +2
Query: 38 ILLPFLLTCAIASAAECENATSLSLMIDSLLATYDRDSPP--DSKIVVNLTLHLRHANI- 208
+LL FLL A E +L L D L A Y P D+ +N+TL + + I
Sbjct: 12 LLLLFLLPAECLGA---EGRLALKLFRD-LFANYTSALRPVADTDQTLNVTLEVTLSQII 67
Query: 209 --RESESTVRIQADLQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLLNAA-ATTA 376
E + + ++ W D L W+ +G + S +WRPD+VL N A A
Sbjct: 68 DMDERNQVLTLYLWIRQEWTDAYLRWDPNAYGGLDAIRIPSSLVWRPDIVLYNKADAQPP 127
Query: 377 GDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXSDEMXFR 550
G + + ++G+V W + + + +P D Q C FGS H ++ R
Sbjct: 128 GSASTNVVLRHDGAVRWDAPAITRSSCRVDVAAFPFDAQHCGLTFGSWTHGGHQLDVR 185
>AF327367-1|AAK14333.1| 450|Homo sapiens nicotinic acetylcholine
receptor subunit alpha 10 protein.
Length = 450
Score = 56.8 bits (131), Expect = 9e-08
Identities = 48/178 (26%), Positives = 75/178 (42%), Gaps = 7/178 (3%)
Frame = +2
Query: 38 ILLPFLLTCAIASAAECENATSLSLMIDSLLATYDRDSPP--DSKIVVNLTLHLRHANI- 208
+LL FLL A E +L L D L A Y P D+ +N+TL + + I
Sbjct: 12 LLLLFLLPAECLGA---EGRLALKLFRD-LFANYTSALRPVADTDQTLNVTLEVTLSQII 67
Query: 209 --RESESTVRIQADLQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLLNAA-ATTA 376
E + + ++ W D L W+ +G + S +WRPD+VL N A A
Sbjct: 68 DMDERNQVLTLYLWIRQEWTDAYLRWDPNAYGGLDAIRIPSSLVWRPDIVLYNKADAQPP 127
Query: 377 GDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXSDEMXFR 550
G + + ++G+V W + + + +P D Q C FGS H ++ R
Sbjct: 128 GSASTNVVLRHDGAVRWDAPAITRSSCRVDVAAFPFDAQHCGLTFGSWTHGGHQLDVR 185
>AF199235-1|AAG00795.2| 450|Homo sapiens nicotinic acetylcholine
receptor subunit alpha 10 protein.
Length = 450
Score = 56.8 bits (131), Expect = 9e-08
Identities = 48/178 (26%), Positives = 75/178 (42%), Gaps = 7/178 (3%)
Frame = +2
Query: 38 ILLPFLLTCAIASAAECENATSLSLMIDSLLATYDRDSPP--DSKIVVNLTLHLRHANI- 208
+LL FLL A E +L L D L A Y P D+ +N+TL + + I
Sbjct: 12 LLLLFLLPAECLGA---EGRLALKLFRD-LFANYTSALRPVADTDQTLNVTLEVTLSQII 67
Query: 209 --RESESTVRIQADLQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLLNAA-ATTA 376
E + + ++ W D L W+ +G + S +WRPD+VL N A A
Sbjct: 68 DMDERNQVLTLYLWIRQEWTDAYLRWDPNAYGGLDAIRIPSSLVWRPDIVLYNKADAQPP 127
Query: 377 GDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXSDEMXFR 550
G + + ++G+V W + + + +P D Q C FGS H ++ R
Sbjct: 128 GSASTNVVLRHDGAVRWDAPAITRSSCRVDVAAFPFDAQHCGLTFGSWTHGGHQLDVR 185
>AC092165-2|AAY24102.1| 517|Homo sapiens unknown protein.
Length = 517
Score = 56.8 bits (131), Expect = 9e-08
Identities = 35/131 (26%), Positives = 62/131 (47%), Gaps = 3/131 (2%)
Frame = +2
Query: 158 DSKIVVNLTLHLRHA-NIRESESTVRIQADLQMNWIDKRLSWNAGEWG-CSTWLVSSERL 331
+ + V L L L + +++E E T+ ++ W D RL WNA E+G S + + +
Sbjct: 49 EESVDVALALTLSNLISLKEVEETLTTNVWIEHGWTDNRLKWNAEEFGNISVLRLPPDMV 108
Query: 332 WRPDVVL-LNAAATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFK 508
W P++VL N + Y+ V + G V W+ + + + +P D Q C+ K
Sbjct: 109 WLPEIVLENNNDGSFQISYSCNVLVYHYGFVYWLPPAIFRSSCPISVTYFPFDWQNCSLK 168
Query: 509 FGSRMHXSDEM 541
F S + + E+
Sbjct: 169 FSSLKYTAKEI 179
>DQ644022-1|ABG35128.1| 456|Homo sapiens 5-HT3 receptor subunit E
splice variant HTR3Ea protein.
Length = 456
Score = 56.0 bits (129), Expect = 2e-07
Identities = 28/100 (28%), Positives = 50/100 (50%), Gaps = 1/100 (1%)
Frame = +2
Query: 245 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 421
L+M W + +SWN E G + ++++ LW PD+ ++ L A VSN G +
Sbjct: 91 LEMVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEGRI 150
Query: 422 SWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXSDEM 541
+ K + + + ++ + +P D Q CT F S ++ D M
Sbjct: 151 RYKKPMKVDSICNLDIFYFPFDQQNCTLTFSSFLYTVDSM 190
>BC101185-1|AAI01186.1| 374|Homo sapiens HTR3E protein protein.
Length = 374
Score = 56.0 bits (129), Expect = 2e-07
Identities = 28/100 (28%), Positives = 50/100 (50%), Gaps = 1/100 (1%)
Frame = +2
Query: 245 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 421
L+M W + +SWN E G + ++++ LW PD+ ++ L A VSN G +
Sbjct: 20 LEMVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEGRI 79
Query: 422 SWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXSDEM 541
+ K + + + ++ + +P D Q CT F S ++ D M
Sbjct: 80 RYKKPMKVDSICNLDIFYFPFDQQNCTLTFSSFLYTVDSM 119
>BC101183-1|AAI01184.1| 471|Homo sapiens 5-hydroxytryptamine
(serotonin) receptor 3, family member E protein.
Length = 471
Score = 56.0 bits (129), Expect = 2e-07
Identities = 28/100 (28%), Positives = 50/100 (50%), Gaps = 1/100 (1%)
Frame = +2
Query: 245 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 421
L+M W + +SWN E G + ++++ LW PD+ ++ L A VSN G +
Sbjct: 106 LEMVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEGRI 165
Query: 422 SWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXSDEM 541
+ K + + + ++ + +P D Q CT F S ++ D M
Sbjct: 166 RYKKPMKVDSICNLDIFYFPFDQQNCTLTFSSFLYTVDSM 205
>BC101182-1|AAI01183.1| 471|Homo sapiens 5-hydroxytryptamine
(serotonin) receptor 3, family member E protein.
Length = 471
Score = 56.0 bits (129), Expect = 2e-07
Identities = 28/100 (28%), Positives = 50/100 (50%), Gaps = 1/100 (1%)
Frame = +2
Query: 245 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 421
L+M W + +SWN E G + ++++ LW PD+ ++ L A VSN G +
Sbjct: 106 LEMVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEGRI 165
Query: 422 SWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXSDEM 541
+ K + + + ++ + +P D Q CT F S ++ D M
Sbjct: 166 RYKKPMKVDSICNLDIFYFPFDQQNCTLTFSSFLYTVDSM 205
>AY159813-1|AAO38167.2| 471|Homo sapiens 5-hydroxytryptamine
serotonin receptor 3E protein.
Length = 471
Score = 56.0 bits (129), Expect = 2e-07
Identities = 28/100 (28%), Positives = 50/100 (50%), Gaps = 1/100 (1%)
Frame = +2
Query: 245 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 421
L+M W + +SWN E G + ++++ LW PD+ ++ L A VSN G +
Sbjct: 106 LEMVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEGRI 165
Query: 422 SWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXSDEM 541
+ K + + + ++ + +P D Q CT F S ++ D M
Sbjct: 166 RYKKPMKVDSICNLDIFYFPFDQQNCTLTFSSFLYTVDSM 205
>BC111802-1|AAI11803.1| 465|Homo sapiens CHRNG protein protein.
Length = 465
Score = 54.8 bits (126), Expect = 4e-07
Identities = 37/135 (27%), Positives = 61/135 (45%), Gaps = 7/135 (5%)
Frame = +2
Query: 47 PFLLTCAIASAAECENATSLSLMIDSLLATYDRDSPPDSKI--VVNLTLHLRHANI---R 211
P LL +A + ++ L+ YD + P + VVN++L L N+
Sbjct: 7 PLLLLLLLAVCLGAQGRNQEERLLADLMQNYDPNLRPAERDSDVVNVSLKLTLTNLISLN 66
Query: 212 ESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAAT-TAGDY 385
E E + ++M W D RL W+ ++ G V S +WRPD+VL N + T + +
Sbjct: 67 EREEALTTNVWIEMQWCDYRLRWDPRDYEGLWVLRVPSTMVWRPDIVLENKSQTYSTNEI 126
Query: 386 ALRARVSNNGSVSWI 430
L+ + S+ WI
Sbjct: 127 DLQLSQEDGQSIEWI 141
>L08485-1|AAA58490.1| 462|Homo sapiens GABA-benzodiazepine receptor
alpha-5-subunit protein.
Length = 462
Score = 54.4 bits (125), Expect = 5e-07
Identities = 38/160 (23%), Positives = 72/160 (45%), Gaps = 7/160 (4%)
Frame = +2
Query: 89 ENATSLSLMIDSLLATYDRDSPPD--SKIV-VNLTLHLRHAN-IRESESTVRIQADLQMN 256
+N T + ++D LL YD P +I V +++ + ++E I + +
Sbjct: 44 DNITIFTRILDGLLDGYDNRLRPGLGERITQVRTDIYVTSFGPVSDTEMEYTIDVFFRQS 103
Query: 257 WIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSW 427
W D+RL + + + ++W PD N + A + R+ ++G++ +
Sbjct: 104 WKDERLRFKGPMQRLPLNNLLASKIWTPDTFFHNGKKSIAHNMTTPNKLLRLEDDGTLLY 163
Query: 428 IKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXSDEMXF 547
RL IS MQL+++P D C KFGS + + E+ +
Sbjct: 164 TMRLTISAECPMQLEDFPMDAHACPLKFGSYAYPNSEVVY 203
>BT009830-1|AAP88832.1| 462|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 5 protein.
Length = 462
Score = 54.4 bits (125), Expect = 5e-07
Identities = 38/160 (23%), Positives = 72/160 (45%), Gaps = 7/160 (4%)
Frame = +2
Query: 89 ENATSLSLMIDSLLATYDRDSPPD--SKIV-VNLTLHLRHAN-IRESESTVRIQADLQMN 256
+N T + ++D LL YD P +I V +++ + ++E I + +
Sbjct: 44 DNITIFTRILDGLLDGYDNRLRPGLGERITQVRTDIYVTSFGPVSDTEMEYTIDVFFRQS 103
Query: 257 WIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSW 427
W D+RL + + + ++W PD N + A + R+ ++G++ +
Sbjct: 104 WKDERLRFKGPMQRLPLNNLLASKIWTPDTFFHNGKKSIAHNMTTPNKLLRLEDDGTLLY 163
Query: 428 IKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXSDEMXF 547
RL IS MQL+++P D C KFGS + + E+ +
Sbjct: 164 TMRLTISAECPMQLEDFPMDAHACPLKFGSYAYPNSEVVY 203
>BC131799-1|AAI31800.1| 447|Homo sapiens 5-hydroxytryptamine
(serotonin) receptor 3, family member C protein.
Length = 447
Score = 54.4 bits (125), Expect = 5e-07
Identities = 26/100 (26%), Positives = 51/100 (51%), Gaps = 1/100 (1%)
Frame = +2
Query: 245 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 421
+ + W + ++WN E G + V +E LW PD+ ++ + L A +S+ G +
Sbjct: 91 MDLVWDNPFINWNPKECVGINKLTVLAENLWLPDIFIVESMDVDQTPSGLTAYISSEGRI 150
Query: 422 SWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXSDEM 541
+ K + +++ ++ + +P D Q CTF F S ++ D M
Sbjct: 151 KYDKPMRVTSICNLDIFYFPFDQQNCTFTFSSFLYTVDSM 190
>BC113422-1|AAI13423.1| 462|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 5 protein.
Length = 462
Score = 54.4 bits (125), Expect = 5e-07
Identities = 38/160 (23%), Positives = 72/160 (45%), Gaps = 7/160 (4%)
Frame = +2
Query: 89 ENATSLSLMIDSLLATYDRDSPPD--SKIV-VNLTLHLRHAN-IRESESTVRIQADLQMN 256
+N T + ++D LL YD P +I V +++ + ++E I + +
Sbjct: 44 DNITIFTRILDGLLDGYDNRLRPGLGERITQVRTDIYVTSFGPVSDTEMEYTIDVFFRQS 103
Query: 257 WIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSW 427
W D+RL + + + ++W PD N + A + R+ ++G++ +
Sbjct: 104 WKDERLRFKGPMQRLPLNNLLASKIWTPDTFFHNGKKSIAHNMTTPNKLLRLEDDGTLLY 163
Query: 428 IKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXSDEMXF 547
RL IS MQL+++P D C KFGS + + E+ +
Sbjct: 164 TMRLTISAECPMQLEDFPMDAHACPLKFGSYAYPNSEVVY 203
>BC111979-1|AAI11980.1| 462|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 5, precursor protein.
Length = 462
Score = 54.4 bits (125), Expect = 5e-07
Identities = 38/160 (23%), Positives = 72/160 (45%), Gaps = 7/160 (4%)
Frame = +2
Query: 89 ENATSLSLMIDSLLATYDRDSPPD--SKIV-VNLTLHLRHAN-IRESESTVRIQADLQMN 256
+N T + ++D LL YD P +I V +++ + ++E I + +
Sbjct: 44 DNITIFTRILDGLLDGYDNRLRPGLGERITQVRTDIYVTSFGPVSDTEMEYTIDVFFRQS 103
Query: 257 WIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSW 427
W D+RL + + + ++W PD N + A + R+ ++G++ +
Sbjct: 104 WKDERLRFKGPMQRLPLNNLLASKIWTPDTFFHNGKKSIAHNMTTPNKLLRLEDDGTLLY 163
Query: 428 IKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXSDEMXF 547
RL IS MQL+++P D C KFGS + + E+ +
Sbjct: 164 TMRLTISAECPMQLEDFPMDAHACPLKFGSYAYPNSEVVY 203
>AY349353-1|AAQ93477.1| 456|Homo sapiens 5-HT3c1 serotonin
receptor-like protein protein.
Length = 456
Score = 54.4 bits (125), Expect = 5e-07
Identities = 28/104 (26%), Positives = 51/104 (49%), Gaps = 1/104 (0%)
Frame = +2
Query: 233 IQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSN 409
+ A L + W + +SWN E G + ++++ LW PD+ ++ L A VSN
Sbjct: 87 MSAILDVVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSN 146
Query: 410 NGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXSDEM 541
G + + K + + + ++ + +P D Q CT F S ++ D M
Sbjct: 147 EGRIRYKKPMKVDSICNLDIFYFPFDQQNCTLTFSSFLYTVDSM 190
>AY349352-1|AAQ93476.1| 441|Homo sapiens 5-HT3c1 serotonin
receptor-like protein protein.
Length = 441
Score = 54.4 bits (125), Expect = 5e-07
Identities = 28/104 (26%), Positives = 51/104 (49%), Gaps = 1/104 (0%)
Frame = +2
Query: 233 IQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSN 409
+ A L + W + +SWN E G + ++++ LW PD+ ++ L A VSN
Sbjct: 72 MSAILDVVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSN 131
Query: 410 NGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXSDEM 541
G + + K + + + ++ + +P D Q CT F S ++ D M
Sbjct: 132 EGRIRYKKPMKVDSICNLDIFYFPFDQQNCTLTFSSFLYTVDSM 175
>AF459285-1|AAL66182.1| 447|Homo sapiens 5-hydroxytryptamine
receptor 3 subunit C protein.
Length = 447
Score = 54.0 bits (124), Expect = 6e-07
Identities = 26/100 (26%), Positives = 50/100 (50%), Gaps = 1/100 (1%)
Frame = +2
Query: 245 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 421
+ + W + ++WN E G + V +E LW PD+ ++ + L A +S+ G +
Sbjct: 91 MDLVWDNPFINWNPKECVGINKLTVLAENLWLPDIFIVESMDVDQTPSGLTAYISSEGRI 150
Query: 422 SWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXSDEM 541
+ K + +++ + + +P D Q CTF F S ++ D M
Sbjct: 151 KYDKPMRVTSICKLDIFYFPFDQQNCTFTFSSFLYTVDSM 190
>Z23141-1|CAA80672.1| 479|Homo sapiens cholinergic receptor,
nicotinic, alpha polypeptide 7 protein.
Length = 479
Score = 53.6 bits (123), Expect = 8e-07
Identities = 37/157 (23%), Positives = 71/157 (45%), Gaps = 2/157 (1%)
Frame = +2
Query: 146 DSPPDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSS 322
DS P + + +L+L L+ ++ E + LQM+W D L WN E+ G T
Sbjct: 24 DSQPLT-VYFSLSL-LQIMDVDEKNQVLTTNIWLQMSWTDHYLQWNVSEYPGVKTVRFPD 81
Query: 323 ERLWRPDVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTC 499
++W+PD++L N+A + V+++G ++ + + + +P D+Q C
Sbjct: 82 GQIWKPDILLYNSADERFDATFHTNVLVNSSGHCQYLPPGIFKSSCYIDVRWFPFDVQHC 141
Query: 500 TFKFGSRMHXSDEMXFRD*XKEYTXCPXPGXWDVTAL 610
KFGS + + + + + G WD+ +
Sbjct: 142 KLKFGSWSYGGWSLDLQMQEADISGYIPNGEWDLVGI 178
>Y08420-1|CAA69697.1| 502|Homo sapiens nicotinic acetylcholine
receptor alpha7 subunit precursor protein.
Length = 502
Score = 53.6 bits (123), Expect = 8e-07
Identities = 37/157 (23%), Positives = 71/157 (45%), Gaps = 2/157 (1%)
Frame = +2
Query: 146 DSPPDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSS 322
DS P + + +L+L L+ ++ E + LQM+W D L WN E+ G T
Sbjct: 47 DSQPLT-VYFSLSL-LQIMDVDEKNQVLTTNIWLQMSWTDHYLQWNVSEYPGVKTVRFPD 104
Query: 323 ERLWRPDVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTC 499
++W+PD++L N+A + V+++G ++ + + + +P D+Q C
Sbjct: 105 GQIWKPDILLYNSADERFDATFHTNVLVNSSGHCQYLPPGIFKSSCYIDVRWFPFDVQHC 164
Query: 500 TFKFGSRMHXSDEMXFRD*XKEYTXCPXPGXWDVTAL 610
KFGS + + + + + G WD+ +
Sbjct: 165 KLKFGSWSYGGWSLDLQMQEADISGYIPNGEWDLVGI 201
>X70297-1|CAA49778.1| 502|Homo sapiens neuronal nicotinic
acetylocholine receptor alpha-7 subunit protein.
Length = 502
Score = 53.6 bits (123), Expect = 8e-07
Identities = 37/157 (23%), Positives = 71/157 (45%), Gaps = 2/157 (1%)
Frame = +2
Query: 146 DSPPDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSS 322
DS P + + +L+L L+ ++ E + LQM+W D L WN E+ G T
Sbjct: 47 DSQPLT-VYFSLSL-LQIMDVDEKNQVLTTNIWLQMSWTDHYLQWNVSEYPGVKTVRFPD 104
Query: 323 ERLWRPDVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTC 499
++W+PD++L N+A + V+++G ++ + + + +P D+Q C
Sbjct: 105 GQIWKPDILLYNSADERFDATFHTNVLVNSSGHCQYLPPGIFKSSCYIDVRWFPFDVQHC 164
Query: 500 TFKFGSRMHXSDEMXFRD*XKEYTXCPXPGXWDVTAL 610
KFGS + + + + + G WD+ +
Sbjct: 165 KLKFGSWSYGGWSLDLQMQEADISGYIPNGEWDLVGI 201
>U62436-1|AAB40114.1| 502|Homo sapiens nicotinic acetylcholine
receptor alpha7 subunit precursor protein.
Length = 502
Score = 53.6 bits (123), Expect = 8e-07
Identities = 37/157 (23%), Positives = 71/157 (45%), Gaps = 2/157 (1%)
Frame = +2
Query: 146 DSPPDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSS 322
DS P + + +L+L L+ ++ E + LQM+W D L WN E+ G T
Sbjct: 47 DSQPLT-VYFSLSL-LQIMDVDEKNQVLTTNIWLQMSWTDHYLQWNVSEYPGVKTVRFPD 104
Query: 323 ERLWRPDVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTC 499
++W+PD++L N+A + V+++G ++ + + + +P D+Q C
Sbjct: 105 GQIWKPDILLYNSADERFDATFHTNVLVNSSGHCQYLPPGIFKSSCYIDVRWFPFDVQHC 164
Query: 500 TFKFGSRMHXSDEMXFRD*XKEYTXCPXPGXWDVTAL 610
KFGS + + + + + G WD+ +
Sbjct: 165 KLKFGSWSYGGWSLDLQMQEADISGYIPNGEWDLVGI 201
>S82769-1|AAB39369.1| 467|Homo sapiens GABAA receptor gamma 3
subunit protein.
Length = 467
Score = 53.6 bits (123), Expect = 8e-07
Identities = 38/158 (24%), Positives = 69/158 (43%), Gaps = 7/158 (4%)
Frame = +2
Query: 98 TSLSLMIDSLLATYDRDSPPDSKI---VVNLTLHLRHAN-IRESESTVRIQADLQMNWID 265
T ++L+++ LL YD+ PD I V+++ +++ + +I W D
Sbjct: 45 TDVTLILNKLLREYDKKLRPDIGIKPTVIDVDIYVNSIGPVSSINMEYQIDIFFAQTWTD 104
Query: 266 KRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKR 436
RL +N+ + +W PD + N+ A R+ N+G + + R
Sbjct: 105 SRLRFNSTMKILTLNSNMVGLIWIPDTIFRNSKTAEAHWITTPNQLLRIWNDGKILYTLR 164
Query: 437 LDISTPISMQLDNWPNDMQTCTFKFGSRMHXSDEMXFR 550
L I+ +QL N+P D +C F S + +EM +R
Sbjct: 165 LTINAECQLQLHNFPMDEHSCPLIFSSYGYPKEEMIYR 202
>AJ586911-1|CAE52911.1| 502|Homo sapiens nicotinic acetylcholine
alpha-7 subunit protein.
Length = 502
Score = 53.6 bits (123), Expect = 8e-07
Identities = 37/157 (23%), Positives = 71/157 (45%), Gaps = 2/157 (1%)
Frame = +2
Query: 146 DSPPDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSS 322
DS P + + +L+L L+ ++ E + LQM+W D L WN E+ G T
Sbjct: 47 DSQPLT-VYFSLSL-LQIMDVDEKNQVLTTNIWLQMSWTDHYLQWNVSEYPGVKTVRFPD 104
Query: 323 ERLWRPDVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTC 499
++W+PD++L N+A + V+++G ++ + + + +P D+Q C
Sbjct: 105 GQIWKPDILLYNSADERFDATFHTNVLVNSSGHCQYLPPGIFKSSCYIDVRWFPFDVQHC 164
Query: 500 TFKFGSRMHXSDEMXFRD*XKEYTXCPXPGXWDVTAL 610
KFGS + + + + + G WD+ +
Sbjct: 165 KLKFGSWSYGGWSLDLQMQEADISGYIPNGEWDLVGI 201
>AF269144-1|AAF99698.1| 467|Homo sapiens GABAA receptor gamma 3
subunit protein.
Length = 467
Score = 53.6 bits (123), Expect = 8e-07
Identities = 38/158 (24%), Positives = 69/158 (43%), Gaps = 7/158 (4%)
Frame = +2
Query: 98 TSLSLMIDSLLATYDRDSPPDSKI---VVNLTLHLRHAN-IRESESTVRIQADLQMNWID 265
T ++L+++ LL YD+ PD I V+++ +++ + +I W D
Sbjct: 45 TDVTLILNKLLREYDKKLRPDIGIKPTVIDVDIYVNSIGPVSSINMEYQIDIFFAQTWTD 104
Query: 266 KRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKR 436
RL +N+ + +W PD + N+ A R+ N+G + + R
Sbjct: 105 SRLRFNSTMKILTLNSNMVGLIWIPDTIFRNSKTAEAHWITTPNQLLRIWNDGKILYTLR 164
Query: 437 LDISTPISMQLDNWPNDMQTCTFKFGSRMHXSDEMXFR 550
L I+ +QL N+P D +C F S + +EM +R
Sbjct: 165 LTINAECQLQLHNFPMDEHSCPLIFSSYGYPKEEMIYR 202
>AF228458-1|AAF63215.1| 449|Homo sapiens GABAA receptor gamma 3
subunit protein.
Length = 449
Score = 53.6 bits (123), Expect = 8e-07
Identities = 38/158 (24%), Positives = 69/158 (43%), Gaps = 7/158 (4%)
Frame = +2
Query: 98 TSLSLMIDSLLATYDRDSPPDSKI---VVNLTLHLRHAN-IRESESTVRIQADLQMNWID 265
T ++L+++ LL YD+ PD I V+++ +++ + +I W D
Sbjct: 27 TDVTLILNKLLREYDKKLRPDIGIKPTVIDVDIYVNSIGPVSSINMEYQIDIFFAQTWTD 86
Query: 266 KRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKR 436
RL +N+ + +W PD + N+ A R+ N+G + + R
Sbjct: 87 SRLRFNSTMKILTLNSNMVGLIWIPDTIFRNSKTAEAHWITTPNQLLRIWNDGKILYTLR 146
Query: 437 LDISTPISMQLDNWPNDMQTCTFKFGSRMHXSDEMXFR 550
L I+ +QL N+P D +C F S + +EM +R
Sbjct: 147 LTINAECQLQLHNFPMDEHSCPLIFSSYGYPKEEMIYR 184
>BC110597-1|AAI10598.1| 411|Homo sapiens ligand-gated ion channel,
zinc activated 1 protein.
Length = 411
Score = 53.2 bits (122), Expect = 1e-06
Identities = 28/102 (27%), Positives = 49/102 (48%)
Frame = +2
Query: 245 LQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVS 424
L+++W+D RL+WN + E LW P + +L A D + +ARV +G V
Sbjct: 86 LRLSWLDTRLAWNTSAHPRHAITLPWESLWTPRLTILEALWVDWRDQSPQARVDQDGHVK 145
Query: 425 WIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXSDEMXFR 550
L T + +L ++P D C+ F + + + E+ F+
Sbjct: 146 LNLALTTETNCNFELLHFPRDHSNCSLSFYALSNTAMELEFQ 187
>AF512521-1|AAO20969.1| 411|Homo sapiens ligand-gated ion channel
subunit protein.
Length = 411
Score = 53.2 bits (122), Expect = 1e-06
Identities = 28/102 (27%), Positives = 49/102 (48%)
Frame = +2
Query: 245 LQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVS 424
L+++W+D RL+WN + E LW P + +L A D + +ARV +G V
Sbjct: 86 LRLSWLDTRLAWNTSAHPRHAITLPWESLWTPRLTILEALWVDWRDQSPQARVDQDGHVK 145
Query: 425 WIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXSDEMXFR 550
L T + +L ++P D C+ F + + + E+ F+
Sbjct: 146 LNLALTTETNCNFELLHFPRDHSNCSLSFYALSNTAMELEFQ 187
>AB223030-1|BAE19924.1| 411|Homo sapiens ligand-gated ion-channel
receptor L2 protein.
Length = 411
Score = 52.8 bits (121), Expect = 1e-06
Identities = 28/102 (27%), Positives = 49/102 (48%)
Frame = +2
Query: 245 LQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVS 424
L+++W+D RL+WN + E LW P + +L A D + +ARV +G V
Sbjct: 86 LRLSWLDTRLAWNTSAHPRHAITLPWESLWTPRLTILEALWVDWRDQSPQARVDQDGHVK 145
Query: 425 WIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXSDEMXFR 550
L T + +L ++P D C+ F + + + E+ F+
Sbjct: 146 LNLALATETNCNFELLHFPRDHSNCSLSFYALSNTAMELEFQ 187
>S77554-1|AAB33983.1| 474|Homo sapiens GABAA receptor beta 2
subunit protein.
Length = 474
Score = 52.4 bits (120), Expect = 2e-06
Identities = 44/182 (24%), Positives = 78/182 (42%), Gaps = 10/182 (5%)
Frame = +2
Query: 32 YIILLPFLLTCAIASAAECENATSLSLM---IDSLLATYDRDSPPD---SKIVVNLTLHL 193
Y + F L A A + +++SL+ +D LL YD PD + V + + +
Sbjct: 9 YFGIWSFPLIIAAVCAQSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDI 68
Query: 194 RHAN-IRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAAT 370
+ + E + Q W DKRLS+N + +++LW PD LN +
Sbjct: 69 ASIDMVSEVNMDYTLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLNDKKS 128
Query: 371 TAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXSDEM 541
++ R+ +G+V + R+ + M L +P D Q CT + S + +D++
Sbjct: 129 FVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDI 188
Query: 542 XF 547
F
Sbjct: 189 EF 190
>S77553-1|AAB33982.1| 512|Homo sapiens GABAA receptor beta 2
subunit protein.
Length = 512
Score = 52.4 bits (120), Expect = 2e-06
Identities = 44/182 (24%), Positives = 78/182 (42%), Gaps = 10/182 (5%)
Frame = +2
Query: 32 YIILLPFLLTCAIASAAECENATSLSLM---IDSLLATYDRDSPPD---SKIVVNLTLHL 193
Y + F L A A + +++SL+ +D LL YD PD + V + + +
Sbjct: 9 YFGIWSFPLIIAAVCAQSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDI 68
Query: 194 RHAN-IRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAAT 370
+ + E + Q W DKRLS+N + +++LW PD LN +
Sbjct: 69 ASIDMVSEVNMDYTLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLNDKKS 128
Query: 371 TAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXSDEM 541
++ R+ +G+V + R+ + M L +P D Q CT + S + +D++
Sbjct: 129 FVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDI 188
Query: 542 XF 547
F
Sbjct: 189 EF 190
>S67368-1|AAB29370.1| 474|Homo sapiens gamma-aminobutyric acid A
receptor beta 2 subunit protein.
Length = 474
Score = 52.4 bits (120), Expect = 2e-06
Identities = 44/182 (24%), Positives = 78/182 (42%), Gaps = 10/182 (5%)
Frame = +2
Query: 32 YIILLPFLLTCAIASAAECENATSLSLM---IDSLLATYDRDSPPD---SKIVVNLTLHL 193
Y + F L A A + +++SL+ +D LL YD PD + V + + +
Sbjct: 9 YFGIWSFPLIIAAVCAQSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDI 68
Query: 194 RHAN-IRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAAT 370
+ + E + Q W DKRLS+N + +++LW PD LN +
Sbjct: 69 ASIDMVSEVNMDYTLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLNDKKS 128
Query: 371 TAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXSDEM 541
++ R+ +G+V + R+ + M L +P D Q CT + S + +D++
Sbjct: 129 FVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDI 188
Query: 542 XF 547
F
Sbjct: 189 EF 190
>BC105639-1|AAI05640.1| 474|Homo sapiens GABRB2 protein protein.
Length = 474
Score = 52.4 bits (120), Expect = 2e-06
Identities = 44/182 (24%), Positives = 78/182 (42%), Gaps = 10/182 (5%)
Frame = +2
Query: 32 YIILLPFLLTCAIASAAECENATSLSLM---IDSLLATYDRDSPPD---SKIVVNLTLHL 193
Y + F L A A + +++SL+ +D LL YD PD + V + + +
Sbjct: 9 YFGIWSFPLIIAAVCAQSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDI 68
Query: 194 RHAN-IRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAAT 370
+ + E + Q W DKRLS+N + +++LW PD LN +
Sbjct: 69 ASIDMVSEVNMDYTLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLNDKKS 128
Query: 371 TAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXSDEM 541
++ R+ +G+V + R+ + M L +P D Q CT + S + +D++
Sbjct: 129 FVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDI 188
Query: 542 XF 547
F
Sbjct: 189 EF 190
>BC099719-1|AAH99719.1| 474|Homo sapiens GABRB2 protein protein.
Length = 474
Score = 52.4 bits (120), Expect = 2e-06
Identities = 44/182 (24%), Positives = 78/182 (42%), Gaps = 10/182 (5%)
Frame = +2
Query: 32 YIILLPFLLTCAIASAAECENATSLSLM---IDSLLATYDRDSPPD---SKIVVNLTLHL 193
Y + F L A A + +++SL+ +D LL YD PD + V + + +
Sbjct: 9 YFGIWSFPLIIAAVCAQSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDI 68
Query: 194 RHAN-IRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAAT 370
+ + E + Q W DKRLS+N + +++LW PD LN +
Sbjct: 69 ASIDMVSEVNMDYTLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLNDKKS 128
Query: 371 TAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXSDEM 541
++ R+ +G+V + R+ + M L +P D Q CT + S + +D++
Sbjct: 129 FVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDI 188
Query: 542 XF 547
F
Sbjct: 189 EF 190
>BC099705-1|AAH99705.1| 474|Homo sapiens GABRB2 protein protein.
Length = 474
Score = 52.4 bits (120), Expect = 2e-06
Identities = 44/182 (24%), Positives = 78/182 (42%), Gaps = 10/182 (5%)
Frame = +2
Query: 32 YIILLPFLLTCAIASAAECENATSLSLM---IDSLLATYDRDSPPD---SKIVVNLTLHL 193
Y + F L A A + +++SL+ +D LL YD PD + V + + +
Sbjct: 9 YFGIWSFPLIIAAVCAQSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDI 68
Query: 194 RHAN-IRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAAT 370
+ + E + Q W DKRLS+N + +++LW PD LN +
Sbjct: 69 ASIDMVSEVNMDYTLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLNDKKS 128
Query: 371 TAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXSDEM 541
++ R+ +G+V + R+ + M L +P D Q CT + S + +D++
Sbjct: 129 FVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDI 188
Query: 542 XF 547
F
Sbjct: 189 EF 190
>BC028629-1|AAH28629.1| 492|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 3 protein.
Length = 492
Score = 52.4 bits (120), Expect = 2e-06
Identities = 36/160 (22%), Positives = 71/160 (44%), Gaps = 7/160 (4%)
Frame = +2
Query: 89 ENATSLSLMIDSLLATYDRDSPP---DSKIVVNLTLHLRHAN-IRESESTVRIQADLQMN 256
+N T + ++D LL YD P D+ V +++ + +++ I +
Sbjct: 62 DNITIFTRILDRLLDGYDNRLRPGLGDAVTEVKTDIYVTSFGPVSDTDMEYTIDVFFRQT 121
Query: 257 WIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSW 427
W D+RL ++ + + ++W PD N + A + R+ +NG++ +
Sbjct: 122 WHDERLKFDGPMKILPLNNLLASKIWTPDTFFHNGKKSVAHNMTTPNKLLRLVDNGTLPY 181
Query: 428 IKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXSDEMXF 547
RL I M L+++P D+ C KFGS + + E+ +
Sbjct: 182 TMRLTIHAECPMHLEDFPMDVHACPLKFGSYAYTTAEVVY 221
>AJ003080-1|CAA05853.1| 238|Homo sapiens serotonin receptor
protein.
Length = 238
Score = 52.4 bits (120), Expect = 2e-06
Identities = 40/171 (23%), Positives = 72/171 (42%), Gaps = 6/171 (3%)
Frame = +2
Query: 38 ILLPFLLTCAIASAAECENATSLSLMIDSLLATYDRDSPP--DSKIVVNLTLHL---RHA 202
+LLP LL A + +L + D LL Y + P D + +++ +
Sbjct: 12 LLLPTLLAQGEARRSRNTTRPALLRLSDYLLTNYRKGVRPVRDWRKPTTVSIDVIVYAIL 71
Query: 203 NIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAG 379
N+ E + + W D+ L WN ++ T L + ++ +W PD+++
Sbjct: 72 NVDEKNQVLTTYIWYRQYWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKS 131
Query: 380 DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXS 532
+ + G V K L + T S+ + N+P D+Q C+ F S +H S
Sbjct: 132 PNIPYVYIRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLHTS 182
>U40583-1|AAA83561.1| 502|Homo sapiens alpha 7 neuronal nicotinic
acetylcholine receptor protein.
Length = 502
Score = 52.0 bits (119), Expect = 3e-06
Identities = 37/157 (23%), Positives = 69/157 (43%), Gaps = 2/157 (1%)
Frame = +2
Query: 146 DSPPDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSS 322
DS P + + +L L L+ ++ E + LQM+W D L WN E+ G T
Sbjct: 47 DSQPLT-VYFSLNL-LQIMDVDEKNQVLTTNIWLQMSWTDHYLQWNVSEYPGVKTVRFPD 104
Query: 323 ERLWRPDVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTC 499
++W+PD++L N+A + V+ +G ++ + + + +P D+Q C
Sbjct: 105 GQIWKPDILLYNSADERFDATFHTNVLVNPSGHCQYLPPGIFKSSCYIDVRWFPFDVQHC 164
Query: 500 TFKFGSRMHXSDEMXFRD*XKEYTXCPXPGXWDVTAL 610
KFGS + + + + + G WD+ +
Sbjct: 165 KLKFGSWSYGGWSLDLQMQEADISGYIPNGEWDLVGI 201
>S82612-1|AAB37533.2| 478|Homo sapiens 5-hydroxytryptamine type 3AS
receptor subunit protein.
Length = 478
Score = 52.0 bits (119), Expect = 3e-06
Identities = 39/169 (23%), Positives = 71/169 (42%), Gaps = 6/169 (3%)
Frame = +2
Query: 38 ILLPFLLTCAIASAAECENATSLSLMIDSLLATYDRDSPP--DSKIVVNLTLHL---RHA 202
+LLP LL A + +L + D LL Y + P D + +++ +
Sbjct: 12 LLLPTLLAQGEARRSRNTTRPALLRLSDYLLTNYTKGVRPVRDWRKPTTVSIDVIVYAIL 71
Query: 203 NIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAG 379
N+ E + + W D+ L WN ++ T L + ++ +W PD+++
Sbjct: 72 NVDEKNQVLTTYIWYRQYWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINELVDVGKS 131
Query: 380 DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMH 526
+ + G V K L + T S+ + N+P D+Q C+ F S +H
Sbjct: 132 PNIPYVYIRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLH 180
>S62908-1|AAB27279.1| 492|Homo sapiens gamma-aminobutyric acidA
receptor alpha 3 subunit protein.
Length = 492
Score = 52.0 bits (119), Expect = 3e-06
Identities = 36/160 (22%), Positives = 71/160 (44%), Gaps = 7/160 (4%)
Frame = +2
Query: 89 ENATSLSLMIDSLLATYDRDSPP---DSKIVVNLTLHLRHAN-IRESESTVRIQADLQMN 256
+N T + ++D LL YD P D+ V +++ + +++ I +
Sbjct: 62 DNITIFTRILDRLLDGYDNRLRPGLGDAVTEVKTDIYVTSFGPVSDTDMEYTIDVFFRQT 121
Query: 257 WIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSW 427
W D+RL ++ + + ++W PD N + A + R+ +NG++ +
Sbjct: 122 WHDERLKFDGPMKILPLNNLLASKIWTPDTFFHNGKKSVAHNMTTPNKLLRLVDNGTLLY 181
Query: 428 IKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXSDEMXF 547
RL I M L+++P D+ C KFGS + + E+ +
Sbjct: 182 TMRLTIHAECPMHLEDFPMDVHACPLKFGSYAYTTAEVVY 221
>M59216-1|AAA35862.1| 474|Homo sapiens gamma-aminobutyric acid
receptor beta-1 subunit protein.
Length = 474
Score = 52.0 bits (119), Expect = 3e-06
Identities = 42/180 (23%), Positives = 78/180 (43%), Gaps = 9/180 (5%)
Frame = +2
Query: 35 IILLPFLLT--CAIASAAECENATSLSLMIDSLLATYDRDSPPD---SKIVVNLTLHLRH 199
++ P ++T C S E N + + +D LL YD PD + V + + +
Sbjct: 12 LLSFPVMITMVCCAHSTNEPSNMSYVKETVDRLLKGYDIRLRPDFGGPPVDVGMRIDVAS 71
Query: 200 AN-IRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTA 376
+ + E + Q +W DKRLS++ + +++LW PD LN +
Sbjct: 72 IDMVSEVNMDYTLTMYFQQSWKDKRLSYSGIPLNLTLDNRVADQLWVPDTYFLNDKKSFV 131
Query: 377 GDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXSDEMXF 547
++ R+ +G+V + R+ + M L +P D Q CT + S + +D++ F
Sbjct: 132 HGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEF 191
>AF385585-1|AAK68111.1| 502|Homo sapiens nicotinic cholinergic
receptor alpha 7 protein.
Length = 502
Score = 52.0 bits (119), Expect = 3e-06
Identities = 37/157 (23%), Positives = 69/157 (43%), Gaps = 2/157 (1%)
Frame = +2
Query: 146 DSPPDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSS 322
DS P + + +L L L+ ++ E + LQM+W D L WN E+ G T
Sbjct: 47 DSQPLT-VYFSLNL-LQIMDVDEKNQVLTTNIWLQMSWTDHYLQWNVSEYPGVKTVRFPD 104
Query: 323 ERLWRPDVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTC 499
++W+PD++L N+A + V+ +G ++ + + + +P D+Q C
Sbjct: 105 GQIWKPDILLYNSADERFDATFHTNVLVNPSGHCQYLPPGIFKSSCYIDVRWFPFDVQHC 164
Query: 500 TFKFGSRMHXSDEMXFRD*XKEYTXCPXPGXWDVTAL 610
KFGS + + + + + G WD+ +
Sbjct: 165 KLKFGSWSYGGWSLDLQMQEADISGYIPNGEWDLVGI 201
>AF166361-1|AAG12455.1| 492|Homo sapiens GABA receptor subunit
alpha 3 protein.
Length = 492
Score = 52.0 bits (119), Expect = 3e-06
Identities = 36/160 (22%), Positives = 71/160 (44%), Gaps = 7/160 (4%)
Frame = +2
Query: 89 ENATSLSLMIDSLLATYDRDSPP---DSKIVVNLTLHLRHAN-IRESESTVRIQADLQMN 256
+N T + ++D LL YD P D+ V +++ + +++ I +
Sbjct: 62 DNITIFTRILDRLLDGYDNRLRPGLGDAVTEVKTDIYVTSFGPVSDTDMEYTIDVFFRQT 121
Query: 257 WIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSW 427
W D+RL ++ + + ++W PD N + A + R+ +NG++ +
Sbjct: 122 WHDERLKFDGPMKILPLNNLLASKIWTPDTFFHNGKKSVAHNMTTPNKLLRLVDNGTLLY 181
Query: 428 IKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXSDEMXF 547
RL I M L+++P D+ C KFGS + + E+ +
Sbjct: 182 TMRLTIHAECPMHLEDFPMDVHACPLKFGSYAYTTAEVVY 221
>X14767-1|CAA32875.1| 474|Homo sapiens GABA-A receptor beta 1
subunit protein.
Length = 474
Score = 51.2 bits (117), Expect = 4e-06
Identities = 42/180 (23%), Positives = 77/180 (42%), Gaps = 9/180 (5%)
Frame = +2
Query: 35 IILLPFLLT--CAIASAAECENATSLSLMIDSLLATYDRDSPPD---SKIVVNLTLHLRH 199
++ P ++T C S E N + +D LL YD PD + V + + +
Sbjct: 12 LLSFPVMITMVCCAHSTNEPSNMPYVKETVDRLLKGYDIRLRPDFGGPPVDVGMRIDVAS 71
Query: 200 AN-IRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTA 376
+ + E + Q +W DKRLS++ + +++LW PD LN +
Sbjct: 72 IDMVSEVNMDYTLTMYFQQSWKDKRLSYSGIPLNLTLDNRVADQLWVPDTYFLNDKKSFV 131
Query: 377 GDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXSDEMXF 547
++ R+ +G+V + R+ + M L +P D Q CT + S + +D++ F
Sbjct: 132 HGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEF 191
>D49394-1|BAA08387.1| 478|Homo sapiens serotonin 5-HT3 receptor
protein.
Length = 478
Score = 51.2 bits (117), Expect = 4e-06
Identities = 39/169 (23%), Positives = 71/169 (42%), Gaps = 6/169 (3%)
Frame = +2
Query: 38 ILLPFLLTCAIASAAECENATSLSLMIDSLLATYDRDSPP--DSKIVVNLTLHL---RHA 202
+LLP LL A + +L + D LL Y + P D + +++ +
Sbjct: 12 LLLPTLLAQGEARRSRNTTRPALLRLSDYLLTNYRKGVRPVRDWRKPTTVSIDVIVYAIL 71
Query: 203 NIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAG 379
N+ E + + W D+ L WN ++ T L + ++ +W PD+++
Sbjct: 72 NVDEKNQVLTTYIWYRQYWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKS 131
Query: 380 DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMH 526
+ + G V K L + T S+ + N+P D+Q C+ F S +H
Sbjct: 132 PNIPYVYIRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLH 180
>BT007204-1|AAP35868.1| 484|Homo sapiens 5-hydroxytryptamine
(serotonin) receptor 3A protein.
Length = 484
Score = 51.2 bits (117), Expect = 4e-06
Identities = 39/169 (23%), Positives = 71/169 (42%), Gaps = 6/169 (3%)
Frame = +2
Query: 38 ILLPFLLTCAIASAAECENATSLSLMIDSLLATYDRDSPP--DSKIVVNLTLHL---RHA 202
+LLP LL A + +L + D LL Y + P D + +++ +
Sbjct: 18 LLLPTLLAQGEARRSRNTTRPALLRLSDYLLTNYRKGVRPVRDWRKPTTVSIDVIVYAIL 77
Query: 203 NIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAG 379
N+ E + + W D+ L WN ++ T L + ++ +W PD+++
Sbjct: 78 NVDEKNQVLTTYIWYRQYWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKS 137
Query: 380 DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMH 526
+ + G V K L + T S+ + N+P D+Q C+ F S +H
Sbjct: 138 PNIPYVYIRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLH 186
>BC113575-1|AAI13576.1| 479|Homo sapiens cholinergic receptor,
nicotinic, alpha 9 protein.
Length = 479
Score = 51.2 bits (117), Expect = 4e-06
Identities = 36/162 (22%), Positives = 73/162 (45%), Gaps = 7/162 (4%)
Frame = +2
Query: 77 AAECENATSLSLMIDSLLATYDRDSPP--DSKIVVNLTLHLRHANIRESESTVRIQAD-- 244
AAE + + + L Y P D+ V+N+TL + + I++ + +I
Sbjct: 22 AAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQITLSQIKDMDERNQILTAYL 81
Query: 245 -LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGD-YALRARVSNNG 415
++ W D L+W+ ++ G + + S+ +WRPD+VL N A + + + +G
Sbjct: 82 WIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKADDESSEPVNTNVVLRYDG 141
Query: 416 SVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXSDEM 541
++W + + + +P D Q C FGS + +++
Sbjct: 142 LITWDAPAITKSSCVVDVTYFPFDNQQCNLTFGSWTYNGNQV 183
>BC113549-1|AAI13550.1| 479|Homo sapiens cholinergic receptor,
nicotinic, alpha 9 protein.
Length = 479
Score = 51.2 bits (117), Expect = 4e-06
Identities = 36/162 (22%), Positives = 73/162 (45%), Gaps = 7/162 (4%)
Frame = +2
Query: 77 AAECENATSLSLMIDSLLATYDRDSPP--DSKIVVNLTLHLRHANIRESESTVRIQAD-- 244
AAE + + + L Y P D+ V+N+TL + + I++ + +I
Sbjct: 22 AAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQITLSQIKDMDERNQILTAYL 81
Query: 245 -LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGD-YALRARVSNNG 415
++ W D L+W+ ++ G + + S+ +WRPD+VL N A + + + +G
Sbjct: 82 WIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKADDESSEPVNTNVVLRYDG 141
Query: 416 SVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXSDEM 541
++W + + + +P D Q C FGS + +++
Sbjct: 142 LITWDAPAITKSSCVVDVTYFPFDNQQCNLTFGSWTYNGNQV 183
>BC004453-1|AAH04453.2| 478|Homo sapiens 5-hydroxytryptamine
(serotonin) receptor 3A protein.
Length = 478
Score = 51.2 bits (117), Expect = 4e-06
Identities = 39/169 (23%), Positives = 71/169 (42%), Gaps = 6/169 (3%)
Frame = +2
Query: 38 ILLPFLLTCAIASAAECENATSLSLMIDSLLATYDRDSPP--DSKIVVNLTLHL---RHA 202
+LLP LL A + +L + D LL Y + P D + +++ +
Sbjct: 12 LLLPTLLAQGEARRSRNTTRPALLRLSDYLLTNYRKGVRPVRDWRKPTTVSIDVIVYAIL 71
Query: 203 NIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAG 379
N+ E + + W D+ L WN ++ T L + ++ +W PD+++
Sbjct: 72 NVDEKNQVLTTYIWYRQYWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKS 131
Query: 380 DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMH 526
+ + G V K L + T S+ + N+P D+Q C+ F S +H
Sbjct: 132 PNIPYVYIRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLH 180
>BC002354-1|AAH02354.1| 478|Homo sapiens 5-hydroxytryptamine
(serotonin) receptor 3A protein.
Length = 478
Score = 51.2 bits (117), Expect = 4e-06
Identities = 39/169 (23%), Positives = 71/169 (42%), Gaps = 6/169 (3%)
Frame = +2
Query: 38 ILLPFLLTCAIASAAECENATSLSLMIDSLLATYDRDSPP--DSKIVVNLTLHL---RHA 202
+LLP LL A + +L + D LL Y + P D + +++ +
Sbjct: 12 LLLPTLLAQGEARRSRNTTRPALLRLSDYLLTNYRKGVRPVRDWRKPTTVSIDVIVYAIL 71
Query: 203 NIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAG 379
N+ E + + W D+ L WN ++ T L + ++ +W PD+++
Sbjct: 72 NVDEKNQVLTTYIWYRQYWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKS 131
Query: 380 DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMH 526
+ + G V K L + T S+ + N+P D+Q C+ F S +H
Sbjct: 132 PNIPYVYIRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLH 180
>AY123244-1|AAM74523.1| 479|Homo sapiens nicotinic acetylcholine
receptor subunit alpha 9 protein.
Length = 479
Score = 51.2 bits (117), Expect = 4e-06
Identities = 36/162 (22%), Positives = 73/162 (45%), Gaps = 7/162 (4%)
Frame = +2
Query: 77 AAECENATSLSLMIDSLLATYDRDSPP--DSKIVVNLTLHLRHANIRESESTVRIQAD-- 244
AAE + + + L Y P D+ V+N+TL + + I++ + +I
Sbjct: 22 AAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQITLSQIKDMDERNQILTAYL 81
Query: 245 -LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGD-YALRARVSNNG 415
++ W D L+W+ ++ G + + S+ +WRPD+VL N A + + + +G
Sbjct: 82 WIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKADDESSEPVNTNVVLRYDG 141
Query: 416 SVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXSDEM 541
++W + + + +P D Q C FGS + +++
Sbjct: 142 LITWDAPAITKSSCVVDVTYFPFDNQQCNLTFGSWTYNGNQV 183
>AJ243342-1|CAB65091.1| 479|Homo sapiens nicotinic acetylcholine
receptor alpha 9 subunit protein.
Length = 479
Score = 51.2 bits (117), Expect = 4e-06
Identities = 36/162 (22%), Positives = 73/162 (45%), Gaps = 7/162 (4%)
Frame = +2
Query: 77 AAECENATSLSLMIDSLLATYDRDSPP--DSKIVVNLTLHLRHANIRESESTVRIQAD-- 244
AAE + + + L Y P D+ V+N+TL + + I++ + +I
Sbjct: 22 AAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQITLSQIKDMDERNQILTAYL 81
Query: 245 -LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGD-YALRARVSNNG 415
++ W D L+W+ ++ G + + S+ +WRPD+VL N A + + + +G
Sbjct: 82 WIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKADDESSEPVNTNVVLRYDG 141
Query: 416 SVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXSDEM 541
++W + + + +P D Q C FGS + +++
Sbjct: 142 LITWDAPAITKSSCVVDVTYFPFDNQQCNLTFGSWTYNGNQV 183
>AJ005205-1|CAA06442.3| 478|Homo sapiens serotonin 3 receptor
protein.
Length = 478
Score = 51.2 bits (117), Expect = 4e-06
Identities = 39/169 (23%), Positives = 71/169 (42%), Gaps = 6/169 (3%)
Frame = +2
Query: 38 ILLPFLLTCAIASAAECENATSLSLMIDSLLATYDRDSPP--DSKIVVNLTLHL---RHA 202
+LLP LL A + +L + D LL Y + P D + +++ +
Sbjct: 12 LLLPTLLAQGEARRSRNTTRPALLRLSDYLLTNYRKGVRPVRDWRKPTTVSIDVIVYAIL 71
Query: 203 NIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAG 379
N+ E + + W D+ L WN ++ T L + ++ +W PD+++
Sbjct: 72 NVDEKNQVLTTYIWYRQYWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKS 131
Query: 380 DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMH 526
+ + G V K L + T S+ + N+P D+Q C+ F S +H
Sbjct: 132 PNIPYVYIRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLH 180
>AJ003079-1|CAA05852.1| 478|Homo sapiens 5-hydroxytryptamine3
receptor protein.
Length = 478
Score = 51.2 bits (117), Expect = 4e-06
Identities = 39/169 (23%), Positives = 71/169 (42%), Gaps = 6/169 (3%)
Frame = +2
Query: 38 ILLPFLLTCAIASAAECENATSLSLMIDSLLATYDRDSPP--DSKIVVNLTLHL---RHA 202
+LLP LL A + +L + D LL Y + P D + +++ +
Sbjct: 12 LLLPTLLAQGEARRSRNTTRPALLRLSDYLLTNYRKGVRPVRDWRKPTTVSIDVIVYAIL 71
Query: 203 NIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAG 379
N+ E + + W D+ L WN ++ T L + ++ +W PD+++
Sbjct: 72 NVDEKNQVLTTYIWYRQYWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKS 131
Query: 380 DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMH 526
+ + G V K L + T S+ + N+P D+Q C+ F S +H
Sbjct: 132 PNIPYVYIRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLH 180
>AJ003078-1|CAA05851.1| 510|Homo sapiens serotonin receptor
protein.
Length = 510
Score = 51.2 bits (117), Expect = 4e-06
Identities = 39/169 (23%), Positives = 71/169 (42%), Gaps = 6/169 (3%)
Frame = +2
Query: 38 ILLPFLLTCAIASAAECENATSLSLMIDSLLATYDRDSPP--DSKIVVNLTLHL---RHA 202
+LLP LL A + +L + D LL Y + P D + +++ +
Sbjct: 12 LLLPTLLAQGEARRSRNTTRPALLRLSDYLLTNYRKGVRPVRDWRKPTTVSIDVIVYAIL 71
Query: 203 NIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAG 379
N+ E + + W D+ L WN ++ T L + ++ +W PD+++
Sbjct: 72 NVDEKNQVLTTYIWYRQYWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKS 131
Query: 380 DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMH 526
+ + G V K L + T S+ + N+P D+Q C+ F S +H
Sbjct: 132 PNIPYVYIRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLH 180
>AF498984-1|AAM21131.1| 478|Homo sapiens 5-hydroxytryptamine
receptor 3A protein.
Length = 478
Score = 51.2 bits (117), Expect = 4e-06
Identities = 39/169 (23%), Positives = 71/169 (42%), Gaps = 6/169 (3%)
Frame = +2
Query: 38 ILLPFLLTCAIASAAECENATSLSLMIDSLLATYDRDSPP--DSKIVVNLTLHL---RHA 202
+LLP LL A + +L + D LL Y + P D + +++ +
Sbjct: 12 LLLPTLLAQGEARRSRNTTRPALLRLSDYLLTNYRKGVRPVRDWRKPTTVSIDVIVYAIL 71
Query: 203 NIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAG 379
N+ E + + W D+ L WN ++ T L + ++ +W PD+++
Sbjct: 72 NVDEKNQVLTTYIWYRQYWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKS 131
Query: 380 DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMH 526
+ + G V K L + T S+ + N+P D+Q C+ F S +H
Sbjct: 132 PNIPYVYIRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLH 180
>AF227732-1|AAF61920.1| 470|Homo sapiens nicotinic acetylcholine
receptor alpha 9 subunit protein.
Length = 470
Score = 51.2 bits (117), Expect = 4e-06
Identities = 36/162 (22%), Positives = 73/162 (45%), Gaps = 7/162 (4%)
Frame = +2
Query: 77 AAECENATSLSLMIDSLLATYDRDSPP--DSKIVVNLTLHLRHANIRESESTVRIQAD-- 244
AAE + + + L Y P D+ V+N+TL + + I++ + +I
Sbjct: 16 AAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQITLSQIKDMDERNQILTAYL 75
Query: 245 -LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGD-YALRARVSNNG 415
++ W D L+W+ ++ G + + S+ +WRPD+VL N A + + + +G
Sbjct: 76 WIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKADDESSEPVNTNVVLRYDG 135
Query: 416 SVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXSDEM 541
++W + + + +P D Q C FGS + +++
Sbjct: 136 LITWDAPAITKSSCVVDVTYFPFDNQQCNLTFGSWTYNGNQV 177
>AC118275-1|AAY40986.1| 479|Homo sapiens unknown protein.
Length = 479
Score = 51.2 bits (117), Expect = 4e-06
Identities = 36/162 (22%), Positives = 73/162 (45%), Gaps = 7/162 (4%)
Frame = +2
Query: 77 AAECENATSLSLMIDSLLATYDRDSPP--DSKIVVNLTLHLRHANIRESESTVRIQAD-- 244
AAE + + + L Y P D+ V+N+TL + + I++ + +I
Sbjct: 22 AAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQITLSQIKDMDERNQILTAYL 81
Query: 245 -LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGD-YALRARVSNNG 415
++ W D L+W+ ++ G + + S+ +WRPD+VL N A + + + +G
Sbjct: 82 WIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKADDESSEPVNTNVVLRYDG 141
Query: 416 SVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXSDEM 541
++W + + + +P D Q C FGS + +++
Sbjct: 142 LITWDAPAITKSSCVVDVTYFPFDNQQCNLTFGSWTYNGNQV 183
>U77731-2|AAB38273.1| 360|Homo sapiens glycine receptor alpha 2B
subunit protein.
Length = 360
Score = 50.8 bits (116), Expect = 6e-06
Identities = 34/135 (25%), Positives = 60/135 (44%), Gaps = 4/135 (2%)
Frame = +2
Query: 155 PDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERL 331
P + N+ ++ +I E+ R+ L+ W D RL+++ S + +
Sbjct: 69 PPVNVTCNIFIN-SFGSIAETTMDYRVNIFLRQQWNDSRLAYSEYPDDSLDLDPSMLDSI 127
Query: 332 WRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCT 502
W+PD+ N D R+S NG V + RL ++ M L N+P D+QTCT
Sbjct: 128 WKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNFPMDVQTCT 187
Query: 503 FKFGSRMHXSDEMXF 547
+ S + +++ F
Sbjct: 188 MQLESFGYTMNDLIF 202
>CR450343-1|CAG29339.1| 452|Homo sapiens GLRA2 protein.
Length = 452
Score = 50.8 bits (116), Expect = 6e-06
Identities = 34/135 (25%), Positives = 60/135 (44%), Gaps = 4/135 (2%)
Frame = +2
Query: 155 PDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERL 331
P + N+ ++ +I E+ R+ L+ W D RL+++ S + +
Sbjct: 69 PPVNVTCNIFIN-SFGSIAETTMDYRVNIFLRQQWNDSRLAYSEYPDDSLDLDPSMLDSI 127
Query: 332 WRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCT 502
W+PD+ N D R+S NG V + RL ++ M L N+P D+QTCT
Sbjct: 128 WKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNFPMDVQTCT 187
Query: 503 FKFGSRMHXSDEMXF 547
+ S + +++ F
Sbjct: 188 MQLESFGYTMNDLIF 202
>AY437084-1|AAR87843.1| 452|Homo sapiens glycine receptor alpha2
subunit B protein.
Length = 452
Score = 50.8 bits (116), Expect = 6e-06
Identities = 34/135 (25%), Positives = 60/135 (44%), Gaps = 4/135 (2%)
Frame = +2
Query: 155 PDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERL 331
P + N+ ++ +I E+ R+ L+ W D RL+++ S + +
Sbjct: 69 PPVNVTCNIFIN-SFGSIAETTMDYRVNIFLRQQWNDSRLAYSEYPDDSLDLDPSMLDSI 127
Query: 332 WRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCT 502
W+PD+ N D R+S NG V + RL ++ M L N+P D+QTCT
Sbjct: 128 WKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNFPMDVQTCT 187
Query: 503 FKFGSRMHXSDEMXF 547
+ S + +++ F
Sbjct: 188 MQLESFGYTMNDLIF 202
>AK122638-1|BAC85499.1| 266|Homo sapiens yte protein of 76kDa)
(LCP2). protein.
Length = 266
Score = 50.8 bits (116), Expect = 6e-06
Identities = 26/89 (29%), Positives = 42/89 (47%)
Frame = +2
Query: 245 LQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVS 424
L+++W+D RL+WN + E LW P + +L A D + +ARV +G V
Sbjct: 87 LRLSWLDTRLAWNTSAHPRHAITLPWESLWTPRLTILEALWVDWRDQSPQARVDQDGHVK 146
Query: 425 WIKRLDISTPISMQLDNWPNDMQTCTFKF 511
L T + +L ++P D C+ F
Sbjct: 147 LNLALTTETNCNFELLHFPRDHSNCSLSF 175
>X52008-1|CAA36257.1| 452|Homo sapiens inhibitory glycine receptor
protein.
Length = 452
Score = 50.4 bits (115), Expect = 8e-06
Identities = 33/135 (24%), Positives = 60/135 (44%), Gaps = 4/135 (2%)
Frame = +2
Query: 155 PDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERL 331
P + N+ ++ ++ E+ R+ L+ W D RL+++ S + +
Sbjct: 69 PPVNVTCNIFIN-SFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPDDSLDLDPSMLDSI 127
Query: 332 WRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCT 502
W+PD+ N D R+S NG V + RL ++ M L N+P D+QTCT
Sbjct: 128 WKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNFPMDVQTCT 187
Query: 503 FKFGSRMHXSDEMXF 547
+ S + +++ F
Sbjct: 188 MQLESFGYTMNDLIF 202
>U77731-1|AAB38272.1| 360|Homo sapiens glycine receptor alpha 2
subunit protein.
Length = 360
Score = 50.4 bits (115), Expect = 8e-06
Identities = 33/135 (24%), Positives = 60/135 (44%), Gaps = 4/135 (2%)
Frame = +2
Query: 155 PDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERL 331
P + N+ ++ ++ E+ R+ L+ W D RL+++ S + +
Sbjct: 69 PPVNVTCNIFIN-SFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPDDSLDLDPSMLDSI 127
Query: 332 WRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCT 502
W+PD+ N D R+S NG V + RL ++ M L N+P D+QTCT
Sbjct: 128 WKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNFPMDVQTCT 187
Query: 503 FKFGSRMHXSDEMXF 547
+ S + +++ F
Sbjct: 188 MQLESFGYTMNDLIF 202
>S81944-1|AAB36480.1| 453|Homo sapiens gamma-aminobutyric acid type
A receptor alpha 6 subunit protein.
Length = 453
Score = 50.4 bits (115), Expect = 8e-06
Identities = 36/156 (23%), Positives = 66/156 (42%), Gaps = 7/156 (4%)
Frame = +2
Query: 101 SLSLMIDSLLATYDRDSPPD---SKIVVNLTLHLRHAN-IRESESTVRIQADLQMNWIDK 268
++S ++D+LL YD P + V +++ + + E + + W D+
Sbjct: 31 NVSRILDNLLEGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTDE 90
Query: 269 RLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRA---RVSNNGSVSWIKRL 439
RL + S + ++W PD N + A + R+ NG++ + RL
Sbjct: 91 RLKFGGPTEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTMRL 150
Query: 440 DISTPISMQLDNWPNDMQTCTFKFGSRMHXSDEMXF 547
I+ M+L N+P D C KFGS + E+ +
Sbjct: 151 TINADCPMRLVNFPMDGHACPLKFGSYAYPKSEIIY 186
>BC099641-1|AAH99641.1| 453|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 6 protein.
Length = 453
Score = 50.4 bits (115), Expect = 8e-06
Identities = 36/156 (23%), Positives = 66/156 (42%), Gaps = 7/156 (4%)
Frame = +2
Query: 101 SLSLMIDSLLATYDRDSPPD---SKIVVNLTLHLRHAN-IRESESTVRIQADLQMNWIDK 268
++S ++D+LL YD P + V +++ + + E + + W D+
Sbjct: 31 NVSRILDNLLEGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTDE 90
Query: 269 RLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRA---RVSNNGSVSWIKRL 439
RL + S + ++W PD N + A + R+ NG++ + RL
Sbjct: 91 RLKFGGPTEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTMRL 150
Query: 440 DISTPISMQLDNWPNDMQTCTFKFGSRMHXSDEMXF 547
I+ M+L N+P D C KFGS + E+ +
Sbjct: 151 TINADCPMRLVNFPMDGHACPLKFGSYAYPKSEIIY 186
>BC099640-1|AAH99640.1| 453|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 6 protein.
Length = 453
Score = 50.4 bits (115), Expect = 8e-06
Identities = 36/156 (23%), Positives = 66/156 (42%), Gaps = 7/156 (4%)
Frame = +2
Query: 101 SLSLMIDSLLATYDRDSPPD---SKIVVNLTLHLRHAN-IRESESTVRIQADLQMNWIDK 268
++S ++D+LL YD P + V +++ + + E + + W D+
Sbjct: 31 NVSRILDNLLEGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTDE 90
Query: 269 RLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRA---RVSNNGSVSWIKRL 439
RL + S + ++W PD N + A + R+ NG++ + RL
Sbjct: 91 RLKFGGPTEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTMRL 150
Query: 440 DISTPISMQLDNWPNDMQTCTFKFGSRMHXSDEMXF 547
I+ M+L N+P D C KFGS + E+ +
Sbjct: 151 TINADCPMRLVNFPMDGHACPLKFGSYAYPKSEIIY 186
>BC096242-1|AAH96242.1| 453|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 6 protein.
Length = 453
Score = 50.4 bits (115), Expect = 8e-06
Identities = 36/156 (23%), Positives = 66/156 (42%), Gaps = 7/156 (4%)
Frame = +2
Query: 101 SLSLMIDSLLATYDRDSPPD---SKIVVNLTLHLRHAN-IRESESTVRIQADLQMNWIDK 268
++S ++D+LL YD P + V +++ + + E + + W D+
Sbjct: 31 NVSRILDNLLEGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTDE 90
Query: 269 RLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRA---RVSNNGSVSWIKRL 439
RL + S + ++W PD N + A + R+ NG++ + RL
Sbjct: 91 RLKFGGPTEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTMRL 150
Query: 440 DISTPISMQLDNWPNDMQTCTFKFGSRMHXSDEMXF 547
I+ M+L N+P D C KFGS + E+ +
Sbjct: 151 TINADCPMRLVNFPMDGHACPLKFGSYAYPKSEIIY 186
>BC096241-1|AAH96241.1| 453|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 6 protein.
Length = 453
Score = 50.4 bits (115), Expect = 8e-06
Identities = 36/156 (23%), Positives = 66/156 (42%), Gaps = 7/156 (4%)
Frame = +2
Query: 101 SLSLMIDSLLATYDRDSPPD---SKIVVNLTLHLRHAN-IRESESTVRIQADLQMNWIDK 268
++S ++D+LL YD P + V +++ + + E + + W D+
Sbjct: 31 NVSRILDNLLEGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTDE 90
Query: 269 RLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRA---RVSNNGSVSWIKRL 439
RL + S + ++W PD N + A + R+ NG++ + RL
Sbjct: 91 RLKFGGPTEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTMRL 150
Query: 440 DISTPISMQLDNWPNDMQTCTFKFGSRMHXSDEMXF 547
I+ M+L N+P D C KFGS + E+ +
Sbjct: 151 TINADCPMRLVNFPMDGHACPLKFGSYAYPKSEIIY 186
>BC032864-1|AAH32864.1| 452|Homo sapiens glycine receptor, alpha 2
protein.
Length = 452
Score = 50.4 bits (115), Expect = 8e-06
Identities = 33/135 (24%), Positives = 60/135 (44%), Gaps = 4/135 (2%)
Frame = +2
Query: 155 PDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERL 331
P + N+ ++ ++ E+ R+ L+ W D RL+++ S + +
Sbjct: 69 PPVNVTCNIFIN-SFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPDDSLDLDPSMLDSI 127
Query: 332 WRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCT 502
W+PD+ N D R+S NG V + RL ++ M L N+P D+QTCT
Sbjct: 128 WKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNFPMDVQTCT 187
Query: 503 FKFGSRMHXSDEMXF 547
+ S + +++ F
Sbjct: 188 MQLESFGYTMNDLIF 202
>AY437083-1|AAR87842.1| 452|Homo sapiens glycine receptor alpha2
subunit A protein.
Length = 452
Score = 50.4 bits (115), Expect = 8e-06
Identities = 33/135 (24%), Positives = 60/135 (44%), Gaps = 4/135 (2%)
Frame = +2
Query: 155 PDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERL 331
P + N+ ++ ++ E+ R+ L+ W D RL+++ S + +
Sbjct: 69 PPVNVTCNIFIN-SFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPDDSLDLDPSMLDSI 127
Query: 332 WRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCT 502
W+PD+ N D R+S NG V + RL ++ M L N+P D+QTCT
Sbjct: 128 WKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNFPMDVQTCT 187
Query: 503 FKFGSRMHXSDEMXF 547
+ S + +++ F
Sbjct: 188 MQLESFGYTMNDLIF 202
>AF053495-1|AAC35290.1| 452|Homo sapiens glycine receptor alpha 2
subunit protein.
Length = 452
Score = 50.4 bits (115), Expect = 8e-06
Identities = 33/135 (24%), Positives = 60/135 (44%), Gaps = 4/135 (2%)
Frame = +2
Query: 155 PDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERL 331
P + N+ ++ ++ E+ R+ L+ W D RL+++ S + +
Sbjct: 69 PPVNVTCNIFIN-SFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPDDSLDLDPSMLDSI 127
Query: 332 WRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCT 502
W+PD+ N D R+S NG V + RL ++ M L N+P D+QTCT
Sbjct: 128 WKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNFPMDVQTCT 187
Query: 503 FKFGSRMHXSDEMXF 547
+ S + +++ F
Sbjct: 188 MQLESFGYTMNDLIF 202
>U30461-1|AAB52519.1| 554|Homo sapiens GABAA receptor subunit
alpha4 protein.
Length = 554
Score = 50.0 bits (114), Expect = 1e-05
Identities = 38/153 (24%), Positives = 67/153 (43%), Gaps = 8/153 (5%)
Frame = +2
Query: 113 MIDSLLATYD-RDSP----PDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLS 277
++DSLL YD R P P +++ ++ + + + E + + WIDKRL
Sbjct: 51 ILDSLLDGYDNRLRPGFGGPVTEVKTDIYV-TSFGPVSDVEMEYTMDVFFRQTWIDKRLK 109
Query: 278 WNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRA---RVSNNGSVSWIKRLDIS 448
++ + ++W PD N + + + R+ NG++ + RL IS
Sbjct: 110 YDGPIEILRLNNMMVTKVWTPDTFFRNGKKSVSHNMTAPNKLFRIMRNGTILYTMRLTIS 169
Query: 449 TPISMQLDNWPNDMQTCTFKFGSRMHXSDEMXF 547
M+L ++P D C KFGS + EM +
Sbjct: 170 AECPMRLVDFPMDGHACPLKFGSYAYPKSEMIY 202
>BC035055-1|AAH35055.1| 554|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 4 protein.
Length = 554
Score = 50.0 bits (114), Expect = 1e-05
Identities = 38/153 (24%), Positives = 67/153 (43%), Gaps = 8/153 (5%)
Frame = +2
Query: 113 MIDSLLATYD-RDSP----PDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLS 277
++DSLL YD R P P +++ ++ + + + E + + WIDKRL
Sbjct: 51 ILDSLLDGYDNRLRPGFGGPVTEVKTDIYV-TSFGPVSDVEMEYTMDVFFRQTWIDKRLK 109
Query: 278 WNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRA---RVSNNGSVSWIKRLDIS 448
++ + ++W PD N + + + R+ NG++ + RL IS
Sbjct: 110 YDGPIEILRLNNMMVTKVWTPDTFFRNGKKSVSHNMTAPNKLFRIMRNGTILYTMRLTIS 169
Query: 449 TPISMQLDNWPNDMQTCTFKFGSRMHXSDEMXF 547
M+L ++P D C KFGS + EM +
Sbjct: 170 AECPMRLVDFPMDGHACPLKFGSYAYPKSEMIY 202
>BC096083-1|AAH96083.1| 198|Homo sapiens CHRNB4 protein protein.
Length = 198
Score = 48.0 bits (109), Expect = 4e-05
Identities = 33/123 (26%), Positives = 59/123 (47%), Gaps = 8/123 (6%)
Frame = +2
Query: 41 LLPFLLTCAIASAAECENATSLSLMIDSLL--ATYD---RDSPPDSKIV-VNLTLHLRHA 202
L+ F L A+ C A + ++D LL Y+ R + S+++ + L L L
Sbjct: 7 LVLFFLV-ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQL 65
Query: 203 -NIRESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTA 376
++ E E + L+ W D RL+WN+ + G + + ++R+W PD+VL N + T
Sbjct: 66 ISVNEREQIMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNKSLRTG 125
Query: 377 GDY 385
+
Sbjct: 126 STW 128
>BC096081-1|AAH96081.1| 198|Homo sapiens CHRNB4 protein protein.
Length = 198
Score = 48.0 bits (109), Expect = 4e-05
Identities = 33/123 (26%), Positives = 59/123 (47%), Gaps = 8/123 (6%)
Frame = +2
Query: 41 LLPFLLTCAIASAAECENATSLSLMIDSLL--ATYD---RDSPPDSKIV-VNLTLHLRHA 202
L+ F L A+ C A + ++D LL Y+ R + S+++ + L L L
Sbjct: 7 LVLFFLV-ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQL 65
Query: 203 -NIRESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTA 376
++ E E + L+ W D RL+WN+ + G + + ++R+W PD+VL N + T
Sbjct: 66 ISVNEREQIMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNKSLRTG 125
Query: 377 GDY 385
+
Sbjct: 126 STW 128
>BC033801-1|AAH33801.1| 452|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, delta protein.
Length = 452
Score = 47.2 bits (107), Expect = 7e-05
Identities = 38/151 (25%), Positives = 65/151 (43%), Gaps = 7/151 (4%)
Frame = +2
Query: 116 IDSLLATYDRDSPPD-SKIVVNLTLHLRHANI---RESESTVRIQADLQMNWIDKRLSWN 283
+D L+A Y R+ P VN+ L L A+I E+ + L +W D RLS+N
Sbjct: 44 LDGLIAGYARNFRPGIGGPPVNVALALEVASIDHISEANMEYTMTVFLHQSWRDSRLSYN 103
Query: 284 AGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTP 454
++LW PD ++NA + D + R+ +G + + R+ +
Sbjct: 104 HTNETLGLDSRFVDKLWLPDTFIVNAKSAWFHDVTVENKLIRLQPDGVILYSIRITSTVA 163
Query: 455 ISMQLDNWPNDMQTCTFKFGSRMHXSDEMXF 547
M L +P D Q C S + S+++ +
Sbjct: 164 CDMDLAKYPMDEQECMLDLESYGYSSEDIVY 194
>AL391845-4|CAI15436.1| 452|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, delta protein.
Length = 452
Score = 47.2 bits (107), Expect = 7e-05
Identities = 38/151 (25%), Positives = 65/151 (43%), Gaps = 7/151 (4%)
Frame = +2
Query: 116 IDSLLATYDRDSPPD-SKIVVNLTLHLRHANI---RESESTVRIQADLQMNWIDKRLSWN 283
+D L+A Y R+ P VN+ L L A+I E+ + L +W D RLS+N
Sbjct: 44 LDGLIAGYARNFRPGIGGPPVNVALALEVASIDHISEANMEYTMTVFLHQSWRDSRLSYN 103
Query: 284 AGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTP 454
++LW PD ++NA + D + R+ +G + + R+ +
Sbjct: 104 HTNETLGLDSRFVDKLWLPDTFIVNAKSAWFHDVTVENKLIRLQPDGVILYSIRITSTVA 163
Query: 455 ISMQLDNWPNDMQTCTFKFGSRMHXSDEMXF 547
M L +P D Q C S + S+++ +
Sbjct: 164 CDMDLAKYPMDEQECMLDLESYGYSSEDIVY 194
>AF016917-1|AAB70007.1| 452|Homo sapiens GABA-A receptor delta
subunit protein.
Length = 452
Score = 47.2 bits (107), Expect = 7e-05
Identities = 38/151 (25%), Positives = 65/151 (43%), Gaps = 7/151 (4%)
Frame = +2
Query: 116 IDSLLATYDRDSPPD-SKIVVNLTLHLRHANI---RESESTVRIQADLQMNWIDKRLSWN 283
+D L+A Y R+ P VN+ L L A+I E+ + L +W D RLS+N
Sbjct: 44 LDGLIAGYARNFRPGIGGPPVNVALALEVASIDHISEANMEYTMTVFLHQSWRDSRLSYN 103
Query: 284 AGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTP 454
++LW PD ++NA + D + R+ +G + + R+ +
Sbjct: 104 HTNETLGLDSRFVDKLWLPDTFIVNAKSAWFHDVTVENKLIRLQPDGVILYSIRITSTVA 163
Query: 455 ISMQLDNWPNDMQTCTFKFGSRMHXSDEMXF 547
M L +P D Q C S + S+++ +
Sbjct: 164 CDMDLAKYPMDEQECMLDLESYGYSSEDIVY 194
>U93917-1|AAC39917.1| 449|Homo sapiens glycine receptor alpha 3
subunit protein.
Length = 449
Score = 46.8 bits (106), Expect = 9e-05
Identities = 45/181 (24%), Positives = 77/181 (42%), Gaps = 11/181 (6%)
Frame = +2
Query: 38 ILLPFLLTCAIASAAECENATSLSLMIDSLLAT---YDRDSPPDSK-IVVNLTLHL---R 196
+LL + T SA S S +D L+ YD P+ K VN+T ++
Sbjct: 21 LLLSLVATKETDSARSRSAPMSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINS 80
Query: 197 HANIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERLWRPDVVLLNAAATT 373
+I E+ R+ L+ W D RL+++ S + +W+PD+ N
Sbjct: 81 FGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGAN 140
Query: 374 AGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXSDEMX 544
+ R+ NG+V + RL ++ M L N+P D+QTC + S + +++
Sbjct: 141 FHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFPMDVQTCIMQLESFGYTMNDLI 200
Query: 545 F 547
F
Sbjct: 201 F 201
>BC114947-1|AAI14948.1| 457|Homo sapiens GLRA1 protein protein.
Length = 457
Score = 46.8 bits (106), Expect = 9e-05
Identities = 46/195 (23%), Positives = 86/195 (44%), Gaps = 17/195 (8%)
Frame = +2
Query: 14 HKMSTTYIILLPFLLTCAIASAAECENATSL------SLMIDSLLAT---YDRDSPPDSK 166
+ +T + L ++ ++A++ E E A S S +D L+ YD P+ K
Sbjct: 2 YSFNTLRLYLWETIVFFSLAASKEAEAARSAPKPMSPSDFLDKLMGRTSGYDARIRPNFK 61
Query: 167 -IVVNLTLHL---RHANIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERL 331
VN++ ++ +I E+ R+ L+ W D RL++N S + +
Sbjct: 62 GPPVNVSCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYNEYPDDSLDLDPSMLDSI 121
Query: 332 WRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCT 502
W+PD+ N + R+S NG+V + R+ ++ M L N+P D+QTC
Sbjct: 122 WKPDLFFANEKGAHFHEITTDNKLLRISRNGNVLYSIRITLTLACPMDLKNFPMDVQTCI 181
Query: 503 FKFGSRMHXSDEMXF 547
+ S + +++ F
Sbjct: 182 MQLESFGYTMNDLIF 196
>BC074980-1|AAH74980.1| 449|Homo sapiens glycine receptor, alpha 1
(startle disease/hyperekplexia) protein.
Length = 449
Score = 46.8 bits (106), Expect = 9e-05
Identities = 46/195 (23%), Positives = 86/195 (44%), Gaps = 17/195 (8%)
Frame = +2
Query: 14 HKMSTTYIILLPFLLTCAIASAAECENATSL------SLMIDSLLAT---YDRDSPPDSK 166
+ +T + L ++ ++A++ E E A S S +D L+ YD P+ K
Sbjct: 2 YSFNTLRLYLWETIVFFSLAASKEAEAARSAPKPMSPSDFLDKLMGRTSGYDARIRPNFK 61
Query: 167 -IVVNLTLHL---RHANIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERL 331
VN++ ++ +I E+ R+ L+ W D RL++N S + +
Sbjct: 62 GPPVNVSCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYNEYPDDSLDLDPSMLDSI 121
Query: 332 WRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCT 502
W+PD+ N + R+S NG+V + R+ ++ M L N+P D+QTC
Sbjct: 122 WKPDLFFANEKGAHFHEITTDNKLLRISRNGNVLYSIRITLTLACPMDLKNFPMDVQTCI 181
Query: 503 FKFGSRMHXSDEMXF 547
+ S + +++ F
Sbjct: 182 MQLESFGYTMNDLIF 196
>BC036086-1|AAH36086.1| 464|Homo sapiens glycine receptor, alpha 3
protein.
Length = 464
Score = 46.8 bits (106), Expect = 9e-05
Identities = 45/181 (24%), Positives = 77/181 (42%), Gaps = 11/181 (6%)
Frame = +2
Query: 38 ILLPFLLTCAIASAAECENATSLSLMIDSLLAT---YDRDSPPDSK-IVVNLTLHL---R 196
+LL + T SA S S +D L+ YD P+ K VN+T ++
Sbjct: 21 LLLSLVATKETDSARSRSAPMSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINS 80
Query: 197 HANIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERLWRPDVVLLNAAATT 373
+I E+ R+ L+ W D RL+++ S + +W+PD+ N
Sbjct: 81 FGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGAN 140
Query: 374 AGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXSDEMX 544
+ R+ NG+V + RL ++ M L N+P D+QTC + S + +++
Sbjct: 141 FHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFPMDVQTCIMQLESFGYTMNDLI 200
Query: 545 F 547
F
Sbjct: 201 F 201
>BC022449-1|AAH22449.1| 474|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, beta 1 protein.
Length = 474
Score = 46.8 bits (106), Expect = 9e-05
Identities = 41/180 (22%), Positives = 77/180 (42%), Gaps = 9/180 (5%)
Frame = +2
Query: 35 IILLPFLLT--CAIASAAECENATSLSLMIDSLLATYDRDSPPD---SKIVVNLTLHLRH 199
++ P ++T C S E N + + +D LL YD PD + V + + +
Sbjct: 12 LLSFPVMITMVCCAHSTNEPSNMSYVKETVDRLLKGYDIRLRPDFGGPPVDVGMRIDVAS 71
Query: 200 AN-IRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTA 376
+ + E + Q +W DKRLS++ + +++L PD LN +
Sbjct: 72 IDMVSEVNMDYTLTMYFQQSWKDKRLSYSGIPLNLTLDNRVADQLCVPDTYFLNDKKSFV 131
Query: 377 GDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXSDEMXF 547
++ R+ +G+V + R+ + M L +P D Q CT + S + +D++ F
Sbjct: 132 HGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEF 191
>AF017724-1|AAC39919.1| 465|Homo sapiens glycine receptor alpha 3
subunit protein.
Length = 465
Score = 46.8 bits (106), Expect = 9e-05
Identities = 45/181 (24%), Positives = 77/181 (42%), Gaps = 11/181 (6%)
Frame = +2
Query: 38 ILLPFLLTCAIASAAECENATSLSLMIDSLLAT---YDRDSPPDSK-IVVNLTLHL---R 196
+LL + T SA S S +D L+ YD P+ K VN+T ++
Sbjct: 21 LLLSLVATKETDSARSRSAPMSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINS 80
Query: 197 HANIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERLWRPDVVLLNAAATT 373
+I E+ R+ L+ W D RL+++ S + +W+PD+ N
Sbjct: 81 FGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGAN 140
Query: 374 AGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXSDEMX 544
+ R+ NG+V + RL ++ M L N+P D+QTC + S + +++
Sbjct: 141 FHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFPMDVQTCIMQLESFGYTMNDLI 200
Query: 545 F 547
F
Sbjct: 201 F 201
>X52009-1|CAA36258.1| 449|Homo sapiens inhibitory glycine receptor
protein.
Length = 449
Score = 46.4 bits (105), Expect = 1e-04
Identities = 30/119 (25%), Positives = 54/119 (45%), Gaps = 4/119 (3%)
Frame = +2
Query: 203 NIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERLWRPDVVLLNAAATTAG 379
+I E+ R+ L+ W D RL++N S + +W+PD+ N
Sbjct: 78 SIAETTMDYRVNIFLRQQWNDPRLAYNEYPDDSLDLDPSMLDSIWKPDLFFANEKGAHFH 137
Query: 380 DYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXSDEMXF 547
+ R+S NG+V + R+ ++ M L N+P D+QTC + S + +++ F
Sbjct: 138 EITTDNKLLRISRNGNVLYSIRITLTLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIF 196
>BC109211-1|AAI09212.1| 632|Homo sapiens gamma-aminobutyric acid
(GABA) receptor, theta protein.
Length = 632
Score = 46.0 bits (104), Expect = 2e-04
Identities = 35/145 (24%), Positives = 60/145 (41%), Gaps = 7/145 (4%)
Frame = +2
Query: 86 CENATSLSLMIDSLLATYDRDSPPD---SKIVVNLTLHLRHAN-IRESESTVRIQADLQM 253
C N + ++D +L+ YD P+ + + V +++++ I E I
Sbjct: 53 CANEAVVQKILDRVLSRYDVRLRPNFGGAPVPVRISIYVTSIEQISEMNMDYTITMFFHQ 112
Query: 254 NWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSN---NGSVS 424
W D RL++ + E+LW PD LN+ D + RV +G+V
Sbjct: 113 TWKDSRLAYYETTLNLTLDYRMHEKLWVPDCYFLNSKDAFVHDVTVENRVFQLHPDGTVR 172
Query: 425 WIKRLDISTPISMQLDNWPNDMQTC 499
+ RL + S+ L +P D Q C
Sbjct: 173 YGIRLTTTAACSLDLHKFPMDKQAC 197
>BC109210-1|AAI09211.1| 632|Homo sapiens gamma-aminobutyric acid
(GABA) receptor, theta protein.
Length = 632
Score = 46.0 bits (104), Expect = 2e-04
Identities = 35/145 (24%), Positives = 60/145 (41%), Gaps = 7/145 (4%)
Frame = +2
Query: 86 CENATSLSLMIDSLLATYDRDSPPD---SKIVVNLTLHLRHAN-IRESESTVRIQADLQM 253
C N + ++D +L+ YD P+ + + V +++++ I E I
Sbjct: 53 CANEAVVQKILDRVLSRYDVRLRPNFGGAPVPVRISIYVTSIEQISEMNMDYTITMFFHQ 112
Query: 254 NWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSN---NGSVS 424
W D RL++ + E+LW PD LN+ D + RV +G+V
Sbjct: 113 TWKDSRLAYYETTLNLTLDYRMHEKLWVPDCYFLNSKDAFVHDVTVENRVFQLHPDGTVR 172
Query: 425 WIKRLDISTPISMQLDNWPNDMQTC 499
+ RL + S+ L +P D Q C
Sbjct: 173 YGIRLTTTAACSLDLHKFPMDKQAC 197
>AF189259-1|AAF70380.1| 632|Homo sapiens GABA-A receptor theta
subunit protein.
Length = 632
Score = 46.0 bits (104), Expect = 2e-04
Identities = 35/145 (24%), Positives = 60/145 (41%), Gaps = 7/145 (4%)
Frame = +2
Query: 86 CENATSLSLMIDSLLATYDRDSPPD---SKIVVNLTLHLRHAN-IRESESTVRIQADLQM 253
C N + ++D +L+ YD P+ + + V +++++ I E I
Sbjct: 53 CANEAVVQKILDRVLSRYDVRLRPNFGGAPVPVRISIYVTSIEQISEMNMDYTITMFFHQ 112
Query: 254 NWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSN---NGSVS 424
W D RL++ + E+LW PD LN+ D + RV +G+V
Sbjct: 113 TWKDSRLAYYETTLNLTLDYRMHEKLWVPDCYFLNSKDAFVHDVTVENRVFQLHPDGTVR 172
Query: 425 WIKRLDISTPISMQLDNWPNDMQTC 499
+ RL + S+ L +P D Q C
Sbjct: 173 YGIRLTTTAACSLDLHKFPMDKQAC 197
>AF144648-1|AAD51172.1| 627|Homo sapiens GABA-A receptor theta
protein.
Length = 627
Score = 46.0 bits (104), Expect = 2e-04
Identities = 35/145 (24%), Positives = 60/145 (41%), Gaps = 7/145 (4%)
Frame = +2
Query: 86 CENATSLSLMIDSLLATYDRDSPPD---SKIVVNLTLHLRHAN-IRESESTVRIQADLQM 253
C N + ++D +L+ YD P+ + + V +++++ I E I
Sbjct: 48 CANEAVVQKILDRVLSRYDVRLRPNFGGAPVPVRISIYVTSIEQISEMNMDYTITMFFHQ 107
Query: 254 NWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSN---NGSVS 424
W D RL++ + E+LW PD LN+ D + RV +G+V
Sbjct: 108 TWKDSRLAYYETTLNLTLDYRMHEKLWVPDCYFLNSKDAFVHDVTVENRVFQLHPDGTVR 167
Query: 425 WIKRLDISTPISMQLDNWPNDMQTC 499
+ RL + S+ L +P D Q C
Sbjct: 168 YGIRLTTTAACSLDLHKFPMDKQAC 192
>BC074795-1|AAH74795.1| 467|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, gamma 2 protein.
Length = 467
Score = 45.2 bits (102), Expect = 3e-04
Identities = 34/156 (21%), Positives = 67/156 (42%), Gaps = 7/156 (4%)
Frame = +2
Query: 104 LSLMIDSLLATYDRDSPPDSKIVVNLTLHLRHANIRESESTVRIQADLQM----NWIDKR 271
+++++++LL YD PD + L + N + + ++ + + W D+R
Sbjct: 66 VTVILNNLLEGYDNKLRPDIGVKPTLIHTDMYVNSIGPVNAINMEYTIDIFFAQTWYDRR 125
Query: 272 LSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYAL---RARVSNNGSVSWIKRLD 442
L +N+ ++W PD N+ A R+ N+G V + RL
Sbjct: 126 LKFNSTIKVLRLNSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYTLRLT 185
Query: 443 ISTPISMQLDNWPNDMQTCTFKFGSRMHXSDEMXFR 550
I +QL N+P D +C +F S + +E+ ++
Sbjct: 186 IDAECQLQLHNFPMDEHSCPLEFSSYGYPREEIVYQ 221
>BC069348-1|AAH69348.1| 467|Homo sapiens gamma-aminobutyric acid A
receptor, gamma 2, isoform 2 precursor protein.
Length = 467
Score = 45.2 bits (102), Expect = 3e-04
Identities = 34/156 (21%), Positives = 67/156 (42%), Gaps = 7/156 (4%)
Frame = +2
Query: 104 LSLMIDSLLATYDRDSPPDSKIVVNLTLHLRHANIRESESTVRIQADLQM----NWIDKR 271
+++++++LL YD PD + L + N + + ++ + + W D+R
Sbjct: 66 VTVILNNLLEGYDNKLRPDIGVKPTLIHTDMYVNSIGPVNAINMEYTIDIFFAQTWYDRR 125
Query: 272 LSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYAL---RARVSNNGSVSWIKRLD 442
L +N+ ++W PD N+ A R+ N+G V + RL
Sbjct: 126 LKFNSTIKVLRLNSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYTLRLT 185
Query: 443 ISTPISMQLDNWPNDMQTCTFKFGSRMHXSDEMXFR 550
I +QL N+P D +C +F S + +E+ ++
Sbjct: 186 IDAECQLQLHNFPMDEHSCPLEFSSYGYPREEIVYQ 221
>BC059389-1|AAH59389.1| 475|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, gamma 2 protein.
Length = 475
Score = 45.2 bits (102), Expect = 3e-04
Identities = 34/156 (21%), Positives = 67/156 (42%), Gaps = 7/156 (4%)
Frame = +2
Query: 104 LSLMIDSLLATYDRDSPPDSKIVVNLTLHLRHANIRESESTVRIQADLQM----NWIDKR 271
+++++++LL YD PD + L + N + + ++ + + W D+R
Sbjct: 66 VTVILNNLLEGYDNKLRPDIGVKPTLIHTDMYVNSIGPVNAINMEYTIDIFFAQTWYDRR 125
Query: 272 LSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYAL---RARVSNNGSVSWIKRLD 442
L +N+ ++W PD N+ A R+ N+G V + RL
Sbjct: 126 LKFNSTIKVLRLNSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYTLRLT 185
Query: 443 ISTPISMQLDNWPNDMQTCTFKFGSRMHXSDEMXFR 550
I +QL N+P D +C +F S + +E+ ++
Sbjct: 186 IDAECQLQLHNFPMDEHSCPLEFSSYGYPREEIVYQ 221
>AF165124-1|AAD50273.1| 467|Homo sapiens gamma-aminobutyric acid A
receptor gamma 2 protein.
Length = 467
Score = 45.2 bits (102), Expect = 3e-04
Identities = 34/156 (21%), Positives = 67/156 (42%), Gaps = 7/156 (4%)
Frame = +2
Query: 104 LSLMIDSLLATYDRDSPPDSKIVVNLTLHLRHANIRESESTVRIQADLQM----NWIDKR 271
+++++++LL YD PD + L + N + + ++ + + W D+R
Sbjct: 66 VTVILNNLLEGYDNKLRPDIGVKPTLIHTDMYVNSIGPVNAINMEYTIDIFFAQTWYDRR 125
Query: 272 LSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYAL---RARVSNNGSVSWIKRLD 442
L +N+ ++W PD N+ A R+ N+G V + RL
Sbjct: 126 LKFNSTIKVLRLNSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYTLRLT 185
Query: 443 ISTPISMQLDNWPNDMQTCTFKFGSRMHXSDEMXFR 550
I +QL N+P D +C +F S + +E+ ++
Sbjct: 186 IDAECQLQLHNFPMDEHSCPLEFSSYGYPREEIVYQ 221
>U95367-1|AAC51357.1| 440|Homo sapiens GABA-A receptor pi subunit
protein.
Length = 440
Score = 44.8 bits (101), Expect = 4e-04
Identities = 40/164 (24%), Positives = 76/164 (46%), Gaps = 9/164 (5%)
Frame = +2
Query: 83 ECENATSLSLM-IDSLLATYDRDSPPD---SKIVVNLTLHLRH-ANIRESESTVRIQADL 247
E + LSL ++L A Y++ P+ + + LTL + ++I ES L
Sbjct: 29 EVGRSDKLSLPGFENLTAGYNKFLRPNFGGEPVQIALTLDIASISSISESNMDYTATIYL 88
Query: 248 QMNWIDKRLSWNAGE-WGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNG 415
+ W+D+RL + + + LV E LW PD ++ + + + + R+ +NG
Sbjct: 89 RQRWMDQRLVFEGNKSFTLDARLV--EFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNG 146
Query: 416 SVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXSDEMXF 547
+V + R+ + +M L +P D QTC + S + +++ F
Sbjct: 147 TVLYALRITTTVACNMDLSKYPMDTQTCKLQLESWGYDGNDVEF 190
>BC109106-1|AAI09107.1| 440|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, pi protein.
Length = 440
Score = 44.8 bits (101), Expect = 4e-04
Identities = 40/164 (24%), Positives = 76/164 (46%), Gaps = 9/164 (5%)
Frame = +2
Query: 83 ECENATSLSLM-IDSLLATYDRDSPPD---SKIVVNLTLHLRH-ANIRESESTVRIQADL 247
E + LSL ++L A Y++ P+ + + LTL + ++I ES L
Sbjct: 29 EVGRSDKLSLPGFENLTAGYNKFLRPNFGGEPVQIALTLDIASISSISESNMDYTATIYL 88
Query: 248 QMNWIDKRLSWNAGE-WGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNG 415
+ W+D+RL + + + LV E LW PD ++ + + + + R+ +NG
Sbjct: 89 RQRWMDQRLVFEGNKSFTLDARLV--EFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNG 146
Query: 416 SVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXSDEMXF 547
+V + R+ + +M L +P D QTC + S + +++ F
Sbjct: 147 TVLYALRITTTVACNMDLSKYPMDTQTCKLQLESWGYDGNDVEF 190
>BC109105-1|AAI09106.1| 440|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, pi protein.
Length = 440
Score = 44.8 bits (101), Expect = 4e-04
Identities = 40/164 (24%), Positives = 76/164 (46%), Gaps = 9/164 (5%)
Frame = +2
Query: 83 ECENATSLSLM-IDSLLATYDRDSPPD---SKIVVNLTLHLRH-ANIRESESTVRIQADL 247
E + LSL ++L A Y++ P+ + + LTL + ++I ES L
Sbjct: 29 EVGRSDKLSLPGFENLTAGYNKFLRPNFGGEPVQIALTLDIASISSISESNMDYTATIYL 88
Query: 248 QMNWIDKRLSWNAGE-WGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNG 415
+ W+D+RL + + + LV E LW PD ++ + + + + R+ +NG
Sbjct: 89 RQRWMDQRLVFEGNKSFTLDARLV--EFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNG 146
Query: 416 SVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXSDEMXF 547
+V + R+ + +M L +P D QTC + S + +++ F
Sbjct: 147 TVLYALRITTTVACNMDLSKYPMDTQTCKLQLESWGYDGNDVEF 190
>BC074865-1|AAH74865.1| 440|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, pi protein.
Length = 440
Score = 44.8 bits (101), Expect = 4e-04
Identities = 40/164 (24%), Positives = 76/164 (46%), Gaps = 9/164 (5%)
Frame = +2
Query: 83 ECENATSLSLM-IDSLLATYDRDSPPD---SKIVVNLTLHLRH-ANIRESESTVRIQADL 247
E + LSL ++L A Y++ P+ + + LTL + ++I ES L
Sbjct: 29 EVGRSDKLSLPGFENLTAGYNKFLRPNFGGEPVQIALTLDIASISSISESNMDYTATIYL 88
Query: 248 QMNWIDKRLSWNAGE-WGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNG 415
+ W+D+RL + + + LV E LW PD ++ + + + + R+ +NG
Sbjct: 89 RQRWMDQRLVFEGNKSFTLDARLV--EFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNG 146
Query: 416 SVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXSDEMXF 547
+V + R+ + +M L +P D QTC + S + +++ F
Sbjct: 147 TVLYALRITTTVACNMDLSKYPMDTQTCKLQLESWGYDGNDVEF 190
>BC074810-1|AAH74810.1| 440|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, pi protein.
Length = 440
Score = 44.8 bits (101), Expect = 4e-04
Identities = 40/164 (24%), Positives = 76/164 (46%), Gaps = 9/164 (5%)
Frame = +2
Query: 83 ECENATSLSLM-IDSLLATYDRDSPPD---SKIVVNLTLHLRH-ANIRESESTVRIQADL 247
E + LSL ++L A Y++ P+ + + LTL + ++I ES L
Sbjct: 29 EVGRSDKLSLPGFENLTAGYNKFLRPNFGGEPVQIALTLDIASISSISESNMDYTATIYL 88
Query: 248 QMNWIDKRLSWNAGE-WGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNG 415
+ W+D+RL + + + LV E LW PD ++ + + + + R+ +NG
Sbjct: 89 RQRWMDQRLVFEGNKSFTLDARLV--EFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNG 146
Query: 416 SVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXSDEMXF 547
+V + R+ + +M L +P D QTC + S + +++ F
Sbjct: 147 TVLYALRITTTVACNMDLSKYPMDTQTCKLQLESWGYDGNDVEF 190
>AF009702-1|AAC24194.1| 440|Homo sapiens GABA-A receptor pi subunit
protein.
Length = 440
Score = 44.8 bits (101), Expect = 4e-04
Identities = 40/164 (24%), Positives = 76/164 (46%), Gaps = 9/164 (5%)
Frame = +2
Query: 83 ECENATSLSLM-IDSLLATYDRDSPPD---SKIVVNLTLHLRH-ANIRESESTVRIQADL 247
E + LSL ++L A Y++ P+ + + LTL + ++I ES L
Sbjct: 29 EVGRSDKLSLPGFENLTAGYNKFLRPNFGGEPVQIALTLDIASISSISESNMDYTATIYL 88
Query: 248 QMNWIDKRLSWNAGE-WGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNG 415
+ W+D+RL + + + LV E LW PD ++ + + + + R+ +NG
Sbjct: 89 RQRWMDQRLVFEGNKSFTLDARLV--EFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNG 146
Query: 416 SVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXSDEMXF 547
+V + R+ + +M L +P D QTC + S + +++ F
Sbjct: 147 TVLYALRITTTVACNMDLSKYPMDTQTCKLQLESWGYDGNDVEF 190
>Z93848-1|CAI41994.1| 376|Homo sapiens glycine receptor, alpha 4
protein.
Length = 376
Score = 44.4 bits (100), Expect = 5e-04
Identities = 32/135 (23%), Positives = 58/135 (42%), Gaps = 4/135 (2%)
Frame = +2
Query: 155 PDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERL 331
P + N+ ++ ++I ++ R+ L+ W D RLS+ S + +
Sbjct: 28 PPVNVTCNIFIN-SFSSITKTTMDYRVNVFLRQQWNDPRLSYREYPDDSLDLDPSMLDSI 86
Query: 332 WRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCT 502
W+PD+ N + R+ NG+V + RL + M L N+P D+QTCT
Sbjct: 87 WKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLILSCLMDLKNFPMDIQTCT 146
Query: 503 FKFGSRMHXSDEMXF 547
+ S + ++ F
Sbjct: 147 MQLESFGYTMKDLVF 161
>BC031087-1|AAH31087.1| 465|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, gamma 1 protein.
Length = 465
Score = 44.4 bits (100), Expect = 5e-04
Identities = 35/156 (22%), Positives = 65/156 (41%), Gaps = 7/156 (4%)
Frame = +2
Query: 104 LSLMIDSLLATYDRDSPPDSKI---VVNLTLHLRHAN-IRESESTVRIQADLQMNWIDKR 271
++ +++SLL YD PD + V+ +++ + I W D R
Sbjct: 64 ITQILNSLLQGYDNKLRPDIGVRPTVIETDVYVNSIGPVDPINMEYTIDIIFAQTWFDSR 123
Query: 272 LSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLD 442
L +N+ ++W PD N+ + A R+ N+G V + RL
Sbjct: 124 LKFNSTMKVLMLNSNMVGKIWIPDTFFRNSRKSDAHWITTPNRLLRIWNDGRVLYTLRLT 183
Query: 443 ISTPISMQLDNWPNDMQTCTFKFGSRMHXSDEMXFR 550
I+ +QL N+P D +C +F S + +E+ ++
Sbjct: 184 INAECYLQLHNFPMDEHSCPLEFSSYGYPKNEIEYK 219
>AL049610-1|CAI42158.1| 376|Homo sapiens glycine receptor, alpha 4
protein.
Length = 376
Score = 44.4 bits (100), Expect = 5e-04
Identities = 32/135 (23%), Positives = 58/135 (42%), Gaps = 4/135 (2%)
Frame = +2
Query: 155 PDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERL 331
P + N+ ++ ++I ++ R+ L+ W D RLS+ S + +
Sbjct: 28 PPVNVTCNIFIN-SFSSITKTTMDYRVNVFLRQQWNDPRLSYREYPDDSLDLDPSMLDSI 86
Query: 332 WRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCT 502
W+PD+ N + R+ NG+V + RL + M L N+P D+QTCT
Sbjct: 87 WKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLILSCLMDLKNFPMDIQTCT 146
Query: 503 FKFGSRMHXSDEMXF 547
+ S + ++ F
Sbjct: 147 MQLESFGYTMKDLVF 161
>X15376-1|CAA33437.1| 467|Homo sapiens GABA-A receptor gamma 2
subunit protein.
Length = 467
Score = 44.0 bits (99), Expect = 7e-04
Identities = 34/156 (21%), Positives = 67/156 (42%), Gaps = 7/156 (4%)
Frame = +2
Query: 104 LSLMIDSLLATYDRDSPPDSKIVVNLTLHLRHANIRESESTVRIQADLQM----NWIDKR 271
+++++++LL YD PD + L + N + + ++ + + W D+R
Sbjct: 66 VTVILNNLLEGYDNKLRPDIGVKPTLIHTDMYVNSIGPVNAINMEYTIDIFFAQMWYDRR 125
Query: 272 LSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYAL---RARVSNNGSVSWIKRLD 442
L +N+ ++W PD N+ A R+ N+G V + RL
Sbjct: 126 LKFNSTIKVLRLNSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYSLRLT 185
Query: 443 ISTPISMQLDNWPNDMQTCTFKFGSRMHXSDEMXFR 550
I +QL N+P D +C +F S + +E+ ++
Sbjct: 186 IDAECQLQLHNFPMDEHSCPLEFSSYGYPREEIVYQ 221
>BC114967-1|AAI14968.1| 366|Homo sapiens GLRA1 protein protein.
Length = 366
Score = 44.0 bits (99), Expect = 7e-04
Identities = 28/110 (25%), Positives = 50/110 (45%), Gaps = 4/110 (3%)
Frame = +2
Query: 230 RIQADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERLWRPDVVLLNAAATTAGDYALR---A 397
R+ L+ W D RL++N S + +W+PD+ N +
Sbjct: 4 RVNIFLRQQWNDPRLAYNEYPDDSLDLDPSMLDSIWKPDLFFANEKGAHFHEITTDNKLL 63
Query: 398 RVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXSDEMXF 547
R+S NG+V + R+ ++ M L N+P D+QTC + S + +++ F
Sbjct: 64 RISRNGNVLYSIRITLTLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIF 113
>AB209359-1|BAD92596.1| 533|Homo sapiens cholinergic receptor,
nicotinic, alpha polypeptide 4 precursor variant
protein.
Length = 533
Score = 34.3 bits (75), Expect = 0.54
Identities = 18/63 (28%), Positives = 28/63 (44%)
Frame = +2
Query: 329 LWRPDVVLLNAAATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFK 508
LW +A A + +A + ++G V W + S+ + +P D Q CT K
Sbjct: 25 LWLCCCTFTSADGDFAVTHLTKAHLFHDGRVQWTPPAIYKSSCSIDVTFFPFDQQNCTMK 84
Query: 509 FGS 517
FGS
Sbjct: 85 FGS 87
>BC096291-1|AAH96291.1| 556|Homo sapiens CHRNA4 protein protein.
Length = 556
Score = 33.5 bits (73), Expect = 0.94
Identities = 17/51 (33%), Positives = 27/51 (52%), Gaps = 4/51 (7%)
Frame = +2
Query: 377 GDYAL----RARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 517
GD+A+ +A + ++G V W + S+ + +P D Q CT KFGS
Sbjct: 60 GDFAVTHLTKAHLFHDGRVQWTPPAIYKSSCSIDVTFFPFDQQNCTMKFGS 110
>U83981-1|AAC25631.1| 674|Homo sapiens apoptosis associated protein
protein.
Length = 674
Score = 31.1 bits (67), Expect = 5.0
Identities = 17/46 (36%), Positives = 22/46 (47%), Gaps = 1/46 (2%)
Frame = -1
Query: 404 IHGRGERSPRRWLQPRLAVPRQASTSVPRTPAKCCSP-TPLRSNSV 270
I+ GE+ P W PRL + Q P TP P TPL++ V
Sbjct: 511 IYVPGEKPPPPWAPPRLPLRLQRRLKRPETPTHDPDPETPLKARKV 556
>CR457259-1|CAG33540.1| 674|Homo sapiens PPP1R15A protein.
Length = 674
Score = 31.1 bits (67), Expect = 5.0
Identities = 17/46 (36%), Positives = 22/46 (47%), Gaps = 1/46 (2%)
Frame = -1
Query: 404 IHGRGERSPRRWLQPRLAVPRQASTSVPRTPAKCCSP-TPLRSNSV 270
I+ GE+ P W PRL + Q P TP P TPL++ V
Sbjct: 511 IYVPGEKPPPPWAPPRLPLRLQRRLKRPETPTHDPDPETPLKARKV 556
>BC003067-1|AAH03067.1| 674|Homo sapiens protein phosphatase 1,
regulatory (inhibitor) subunit 15A protein.
Length = 674
Score = 31.1 bits (67), Expect = 5.0
Identities = 17/46 (36%), Positives = 22/46 (47%), Gaps = 1/46 (2%)
Frame = -1
Query: 404 IHGRGERSPRRWLQPRLAVPRQASTSVPRTPAKCCSP-TPLRSNSV 270
I+ GE+ P W PRL + Q P TP P TPL++ V
Sbjct: 511 IYVPGEKPPPPWAPPRLPLRLQRRLKRPETPTHDPDPETPLKARKV 556
>AK001361-1|BAA91649.1| 674|Homo sapiens protein ( Homo sapiens
cDNA FLJ10499 fis, clone NT2RP2000346, weakly similar to
MYELOID DIFFERENTIATION PRIMARY RESPONSE PROTEIN MYD116.
).
Length = 674
Score = 31.1 bits (67), Expect = 5.0
Identities = 17/46 (36%), Positives = 22/46 (47%), Gaps = 1/46 (2%)
Frame = -1
Query: 404 IHGRGERSPRRWLQPRLAVPRQASTSVPRTPAKCCSP-TPLRSNSV 270
I+ GE+ P W PRL + Q P TP P TPL++ V
Sbjct: 511 IYVPGEKPPPPWAPPRLPLRLQRRLKRPETPTHDPDPETPLKARKV 556
>BC146774-1|AAI46775.1| 1114|Homo sapiens GPR124 protein protein.
Length = 1114
Score = 30.7 bits (66), Expect = 6.7
Identities = 16/55 (29%), Positives = 26/55 (47%), Gaps = 1/55 (1%)
Frame = +2
Query: 278 WNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNN-GSVSWIKRL 439
W +GEW C+ + + ++V+L T+ Y RV+NN G W + L
Sbjct: 314 WASGEWECTVSMAQGNASKKVEIVVLE----TSASYCPAERVANNRGDFRWPRTL 364
>AY181242-1|AAO27354.1| 1331|Homo sapiens G protein-coupled receptor
124 protein.
Length = 1331
Score = 30.7 bits (66), Expect = 6.7
Identities = 16/55 (29%), Positives = 26/55 (47%), Gaps = 1/55 (1%)
Frame = +2
Query: 278 WNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNN-GSVSWIKRL 439
W +GEW C+ + + ++V+L T+ Y RV+NN G W + L
Sbjct: 314 WASGEWECTVSMAQGNASKKVEIVVLE----TSASYCPAERVANNRGDFRWPRTL 364
>AK074099-1|BAB84925.1| 1310|Homo sapiens FLJ00170 protein protein.
Length = 1310
Score = 30.7 bits (66), Expect = 6.7
Identities = 16/55 (29%), Positives = 26/55 (47%), Gaps = 1/55 (1%)
Frame = +2
Query: 278 WNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNN-GSVSWIKRL 439
W +GEW C+ + + ++V+L T+ Y RV+NN G W + L
Sbjct: 293 WASGEWECTVSMAQGNASKKVEIVVLE----TSASYCPAERVANNRGDFRWPRTL 343
>AF378755-1|AAL11992.1| 1331|Homo sapiens tumor endothelial marker 5
precursor protein.
Length = 1331
Score = 30.7 bits (66), Expect = 6.7
Identities = 16/55 (29%), Positives = 26/55 (47%), Gaps = 1/55 (1%)
Frame = +2
Query: 278 WNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNN-GSVSWIKRL 439
W +GEW C+ + + ++V+L T+ Y RV+NN G W + L
Sbjct: 314 WASGEWECTVSMAQGNASKKVEIVVLE----TSASYCPAERVANNRGDFRWPRTL 364
>AB040964-1|BAA96055.2| 1206|Homo sapiens KIAA1531 protein protein.
Length = 1206
Score = 30.7 bits (66), Expect = 6.7
Identities = 16/55 (29%), Positives = 26/55 (47%), Gaps = 1/55 (1%)
Frame = +2
Query: 278 WNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNN-GSVSWIKRL 439
W +GEW C+ + + ++V+L T+ Y RV+NN G W + L
Sbjct: 406 WASGEWECTVSMAQGNASKKVEIVVLE----TSASYCPAERVANNRGDFRWPRTL 456
>AK122582-1|BAC56923.1| 1383|Homo sapiens FLJ00269 protein protein.
Length = 1383
Score = 30.3 bits (65), Expect = 8.8
Identities = 13/38 (34%), Positives = 18/38 (47%)
Frame = -1
Query: 401 HGRGERSPRRWLQPRLAVPRQASTSVPRTPAKCCSPTP 288
HG + SP W Q + + P + P P +CCS P
Sbjct: 256 HGGRDCSPTCWEQGKCSGPAEQEKRGPSFPKECCSQGP 293
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 115,936,691
Number of Sequences: 237096
Number of extensions: 2754052
Number of successful extensions: 8609
Number of sequences better than 10.0: 188
Number of HSP's better than 10.0 without gapping: 6631
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 8356
length of database: 76,859,062
effective HSP length: 89
effective length of database: 55,757,518
effective search space used: 10259383312
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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