Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BmNP08_FL5_H11
(873 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
AJ306454-1|CAC34819.1| 497|Homo sapiens neuronal nicotinic acet... 62 3e-09
Y08416-1|CAA69693.1| 498|Homo sapiens nicotinic acetylcholine r... 60 1e-08
U62439-1|AAB40117.1| 498|Homo sapiens nicotinic acetylcholine r... 60 1e-08
U48861-1|AAA92123.1| 498|Homo sapiens beta 4 nicotinic acetylch... 60 1e-08
BC096082-1|AAH96082.1| 498|Homo sapiens cholinergic receptor, n... 60 1e-08
BC096080-1|AAH96080.1| 498|Homo sapiens cholinergic receptor, n... 60 1e-08
AF306329-1|AAL02062.1| 498|Homo sapiens neuronal nicotinic acet... 60 1e-08
X68275-1|CAA48336.1| 451|Homo sapiens nicotinic receptor beta 4... 56 2e-07
X14830-1|CAA32939.1| 501|Homo sapiens protein ( Human mRNA for ... 56 2e-07
BC011371-1|AAH11371.1| 501|Homo sapiens cholinergic receptor, n... 56 2e-07
BC023553-1|AAH23553.1| 501|Homo sapiens cholinergic receptor, n... 54 5e-07
Y08417-1|CAA69694.1| 458|Homo sapiens nicotinic acetylcholine r... 54 9e-07
X67513-1|CAA47851.1| 423|Homo sapiens nicotinic acetylcholine ... 54 9e-07
U62438-1|AAB40116.1| 458|Homo sapiens nicotinic acetylcholine r... 54 9e-07
BC069788-1|AAH69788.1| 458|Homo sapiens cholinergic receptor, n... 54 9e-07
BC069703-1|AAH69703.1| 458|Homo sapiens cholinergic receptor, n... 54 9e-07
BC069681-1|AAH69681.1| 458|Homo sapiens cholinergic receptor, n... 54 9e-07
AF140765-1|AAD33063.1| 458|Homo sapiens neuronal acetylcholine ... 54 9e-07
M86383-1|AAC84176.1| 502|Homo sapiens nicotinic acetylcholine r... 53 1e-06
BT006897-1|AAP35543.1| 505|Homo sapiens cholinergic receptor, n... 53 1e-06
BT006646-1|AAP35292.1| 489|Homo sapiens cholinergic receptor, n... 53 1e-06
BC006114-1|AAH06114.1| 489|Homo sapiens CHRNA3 protein protein. 53 1e-06
BC002996-1|AAH02996.1| 505|Homo sapiens cholinergic receptor, n... 53 1e-06
BC001642-1|AAH01642.1| 505|Homo sapiens cholinergic receptor, n... 53 1e-06
BC000513-1|AAH00513.1| 505|Homo sapiens cholinergic receptor, n... 53 1e-06
AF385584-1|AAK68110.1| 489|Homo sapiens nicotinic cholinergic r... 53 1e-06
Y16281-1|CAA76154.1| 529|Homo sapiens nicotinic acetylcholine r... 52 3e-06
Y00762-1|CAA68731.1| 457|Homo sapiens protein ( Human mRNA for ... 52 3e-06
X02502-1|CAA26344.1| 457|Homo sapiens acetylcholine receptor pr... 52 3e-06
U62431-1|AAB40109.1| 529|Homo sapiens nicotinic acetylcholine r... 52 3e-06
S77094-1|AAD14247.1| 457|Homo sapiens nicotinic acetylcholine r... 52 3e-06
BC006314-1|AAH06314.1| 269|Homo sapiens CHRNA1 protein protein. 52 3e-06
AC018890-1|AAY14687.1| 457|Homo sapiens unknown protein. 52 3e-06
Y08418-1|CAA69695.1| 503|Homo sapiens nicotinic acetylcholine r... 52 4e-06
X66403-1|CAA47030.1| 493|Homo sapiens acetylcholine receptor ep... 52 4e-06
X53559-1|CAA37625.1| 474|Homo sapiens neuronal nicotinic acetyl... 52 4e-06
U62432-1|AAB40110.1| 504|Homo sapiens nicotinic acetylcholine r... 52 4e-06
M37981-1|AAA59942.1| 503|Homo sapiens neuronal nicotinic acetyl... 52 4e-06
BC098443-1|AAH98443.1| 504|Homo sapiens cholinergic receptor, n... 52 4e-06
AJ007783-1|CAA07682.1| 504|Homo sapiens nicotinic acetylcholine... 52 4e-06
AF105999-1|AAD24503.1| 493|Homo sapiens acetylcholine receptor ... 52 4e-06
Y08419-1|CAA69696.1| 468|Homo sapiens nicotinic acetylcholine r... 51 6e-06
U62434-1|AAB40112.1| 468|Homo sapiens nicotinic acetylcholine r... 51 6e-06
BC033639-1|AAH33639.1| 468|Homo sapiens cholinergic receptor, n... 51 6e-06
AJ306481-1|CAC34820.1| 468|Homo sapiens neuronal nicotinic acet... 51 6e-06
AJ001935-1|CAA05108.1| 504|Homo sapiens CHRNB2 protein. 50 1e-05
Y16282-1|CAA76155.1| 494|Homo sapiens nicotinic acetylcholine r... 50 1e-05
X01715-1|CAA25861.1| 520|Homo sapiens acetylcholine receptor ga... 50 1e-05
U62435-1|AAB40113.1| 494|Homo sapiens nicotinic acetylcholine r... 50 1e-05
M83712-1|AAA58357.1| 468|Homo sapiens nicotinic receptor alpha ... 50 1e-05
BC014456-1|AAH14456.1| 494|Homo sapiens cholinergic receptor, n... 50 1e-05
AC092165-3|AAY24103.1| 520|Homo sapiens unknown protein. 50 1e-05
AB079251-1|BAC06855.1| 494|Homo sapiens Nicotinic acetylcholine... 50 1e-05
BC111802-1|AAI11803.1| 465|Homo sapiens CHRNG protein protein. 49 2e-05
BC110597-1|AAI10598.1| 411|Homo sapiens ligand-gated ion channe... 49 2e-05
AK122638-1|BAC85499.1| 266|Homo sapiens yte protein of 76kDa) (... 49 2e-05
AF512521-1|AAO20969.1| 411|Homo sapiens ligand-gated ion channe... 49 2e-05
Y08421-1|CAA69698.1| 627|Homo sapiens nicotinic acetylcholine r... 49 3e-05
X89741-1|CAA61893.1| 627|Homo sapiens neuronal acetylcholine re... 49 3e-05
X87629-1|CAA60959.1| 602|Homo sapiens nicotinic acetylcholine r... 49 3e-05
U62433-1|AAB40111.1| 627|Homo sapiens nicotinic acetylcholine r... 49 3e-05
L35901-1|AAA64743.1| 627|Homo sapiens nicotinic acetylcholine r... 49 3e-05
DQ093071-1|AAY88737.1| 627|Homo sapiens cholinergic receptor, n... 49 3e-05
BC096290-1|AAH96290.1| 627|Homo sapiens cholinergic receptor, n... 49 3e-05
AB223030-1|BAE19924.1| 411|Homo sapiens ligand-gated ion-channe... 49 3e-05
Y08415-1|CAA69692.1| 502|Homo sapiens nicotinic acetylcholine r... 48 3e-05
X53179-1|CAA37320.1| 502|Homo sapiens precursor peptide (AA -25... 48 3e-05
U62437-1|AAB40115.1| 502|Homo sapiens nicotinic acetylcholine r... 48 3e-05
BC075041-1|AAH75041.1| 502|Homo sapiens cholinergic receptor, n... 48 3e-05
BC075040-1|AAH75040.1| 502|Homo sapiens cholinergic receptor, n... 48 3e-05
AL592078-3|CAI16184.1| 502|Homo sapiens cholinergic receptor, n... 48 3e-05
AF077186-1|AAD45422.1| 502|Homo sapiens neuronal nicotinic acet... 48 3e-05
X55019-1|CAA38759.1| 517|Homo sapiens acetylcholine receptor de... 48 6e-05
BC093925-1|AAH93925.1| 517|Homo sapiens cholinergic receptor, n... 48 6e-05
BC093923-1|AAH93923.1| 517|Homo sapiens cholinergic receptor, n... 48 6e-05
AC092165-2|AAY24102.1| 517|Homo sapiens unknown protein. 48 6e-05
M59216-1|AAA35862.1| 474|Homo sapiens gamma-aminobutyric acid r... 47 1e-04
DQ644022-1|ABG35128.1| 456|Homo sapiens 5-HT3 receptor subunit ... 47 1e-04
BC101185-1|AAI01186.1| 374|Homo sapiens HTR3E protein protein. 47 1e-04
BC101183-1|AAI01184.1| 471|Homo sapiens 5-hydroxytryptamine (se... 47 1e-04
BC101182-1|AAI01183.1| 471|Homo sapiens 5-hydroxytryptamine (se... 47 1e-04
AY159813-1|AAO38167.2| 471|Homo sapiens 5-hydroxytryptamine ser... 47 1e-04
X14767-1|CAA32875.1| 474|Homo sapiens GABA-A receptor beta 1 su... 46 2e-04
S77554-1|AAB33983.1| 474|Homo sapiens GABAA receptor beta 2 sub... 46 2e-04
S77553-1|AAB33982.1| 512|Homo sapiens GABAA receptor beta 2 sub... 46 2e-04
S67368-1|AAB29370.1| 474|Homo sapiens gamma-aminobutyric acid A... 46 2e-04
BC105639-1|AAI05640.1| 474|Homo sapiens GABRB2 protein protein. 46 2e-04
BC099719-1|AAH99719.1| 474|Homo sapiens GABRB2 protein protein. 46 2e-04
BC099705-1|AAH99705.1| 474|Homo sapiens GABRB2 protein protein. 46 2e-04
U77731-2|AAB38273.1| 360|Homo sapiens glycine receptor alpha 2B... 46 2e-04
CR450343-1|CAG29339.1| 452|Homo sapiens GLRA2 protein. 46 2e-04
AY437084-1|AAR87843.1| 452|Homo sapiens glycine receptor alpha2... 46 2e-04
X52008-1|CAA36257.1| 452|Homo sapiens inhibitory glycine recept... 45 3e-04
U77731-1|AAB38272.1| 360|Homo sapiens glycine receptor alpha 2 ... 45 3e-04
BC032864-1|AAH32864.1| 452|Homo sapiens glycine receptor, alpha... 45 3e-04
AY437083-1|AAR87842.1| 452|Homo sapiens glycine receptor alpha2... 45 3e-04
AF053495-1|AAC35290.1| 452|Homo sapiens glycine receptor alpha ... 45 3e-04
AY349353-1|AAQ93477.1| 456|Homo sapiens 5-HT3c1 serotonin recep... 45 4e-04
AY349352-1|AAQ93476.1| 441|Homo sapiens 5-HT3c1 serotonin recep... 45 4e-04
BC096083-1|AAH96083.1| 198|Homo sapiens CHRNB4 protein protein. 44 5e-04
BC096081-1|AAH96081.1| 198|Homo sapiens CHRNB4 protein protein. 44 5e-04
BC114947-1|AAI14948.1| 457|Homo sapiens GLRA1 protein protein. 43 0.002
BC074980-1|AAH74980.1| 449|Homo sapiens glycine receptor, alpha... 43 0.002
S82769-1|AAB39369.1| 467|Homo sapiens GABAA receptor gamma 3 su... 42 0.002
AF269144-1|AAF99698.1| 467|Homo sapiens GABAA receptor gamma 3 ... 42 0.002
AF228458-1|AAF63215.1| 449|Homo sapiens GABAA receptor gamma 3 ... 42 0.002
BC033801-1|AAH33801.1| 452|Homo sapiens gamma-aminobutyric acid... 42 0.003
AL391845-4|CAI15436.1| 452|Homo sapiens gamma-aminobutyric acid... 42 0.003
AF016917-1|AAB70007.1| 452|Homo sapiens GABA-A receptor delta s... 42 0.003
BC022449-1|AAH22449.1| 474|Homo sapiens gamma-aminobutyric acid... 42 0.004
S82612-1|AAB37533.2| 478|Homo sapiens 5-hydroxytryptamine type ... 41 0.005
X52009-1|CAA36258.1| 449|Homo sapiens inhibitory glycine recept... 41 0.007
D49394-1|BAA08387.1| 478|Homo sapiens serotonin 5-HT3 receptor ... 41 0.007
BT007204-1|AAP35868.1| 484|Homo sapiens 5-hydroxytryptamine (se... 41 0.007
BC004453-1|AAH04453.2| 478|Homo sapiens 5-hydroxytryptamine (se... 41 0.007
BC002354-1|AAH02354.1| 478|Homo sapiens 5-hydroxytryptamine (se... 41 0.007
AJ005205-1|CAA06442.3| 478|Homo sapiens serotonin 3 receptor pr... 41 0.007
AJ003080-1|CAA05853.1| 238|Homo sapiens serotonin receptor prot... 41 0.007
AJ003079-1|CAA05852.1| 478|Homo sapiens 5-hydroxytryptamine3 re... 41 0.007
AJ003078-1|CAA05851.1| 510|Homo sapiens serotonin receptor prot... 41 0.007
AF498984-1|AAM21131.1| 478|Homo sapiens 5-hydroxytryptamine rec... 41 0.007
Z23141-1|CAA80672.1| 479|Homo sapiens cholinergic receptor, nic... 40 0.009
Y08420-1|CAA69697.1| 502|Homo sapiens nicotinic acetylcholine r... 40 0.009
X70297-1|CAA49778.1| 502|Homo sapiens neuronal nicotinic acetyl... 40 0.009
U95367-1|AAC51357.1| 440|Homo sapiens GABA-A receptor pi subuni... 40 0.009
U62436-1|AAB40114.1| 502|Homo sapiens nicotinic acetylcholine r... 40 0.009
BC109106-1|AAI09107.1| 440|Homo sapiens gamma-aminobutyric acid... 40 0.009
BC109105-1|AAI09106.1| 440|Homo sapiens gamma-aminobutyric acid... 40 0.009
BC074865-1|AAH74865.1| 440|Homo sapiens gamma-aminobutyric acid... 40 0.009
BC074810-1|AAH74810.1| 440|Homo sapiens gamma-aminobutyric acid... 40 0.009
AJ586911-1|CAE52911.1| 502|Homo sapiens nicotinic acetylcholine... 40 0.009
AF009702-1|AAC24194.1| 440|Homo sapiens GABA-A receptor pi subu... 40 0.009
Z93848-1|CAI41994.1| 376|Homo sapiens glycine receptor, alpha 4... 40 0.012
AL049610-1|CAI42158.1| 376|Homo sapiens glycine receptor, alpha... 40 0.012
U93917-1|AAC39917.1| 449|Homo sapiens glycine receptor alpha 3 ... 40 0.016
U40583-1|AAA83561.1| 502|Homo sapiens alpha 7 neuronal nicotini... 40 0.016
BC036086-1|AAH36086.1| 464|Homo sapiens glycine receptor, alpha... 40 0.016
AF385585-1|AAK68111.1| 502|Homo sapiens nicotinic cholinergic r... 40 0.016
AF017724-1|AAC39919.1| 465|Homo sapiens glycine receptor alpha ... 40 0.016
BC114967-1|AAI14968.1| 366|Homo sapiens GLRA1 protein protein. 38 0.036
BC074795-1|AAH74795.1| 467|Homo sapiens gamma-aminobutyric acid... 38 0.063
BC069348-1|AAH69348.1| 467|Homo sapiens gamma-aminobutyric acid... 38 0.063
BC059389-1|AAH59389.1| 475|Homo sapiens gamma-aminobutyric acid... 38 0.063
AF165124-1|AAD50273.1| 467|Homo sapiens gamma-aminobutyric acid... 38 0.063
S81944-1|AAB36480.1| 453|Homo sapiens gamma-aminobutyric acid t... 37 0.083
BC099641-1|AAH99641.1| 453|Homo sapiens gamma-aminobutyric acid... 37 0.083
BC099640-1|AAH99640.1| 453|Homo sapiens gamma-aminobutyric acid... 37 0.083
BC096242-1|AAH96242.1| 453|Homo sapiens gamma-aminobutyric acid... 37 0.083
BC096241-1|AAH96241.1| 453|Homo sapiens gamma-aminobutyric acid... 37 0.083
X15376-1|CAA33437.1| 467|Homo sapiens GABA-A receptor gamma 2 s... 37 0.11
BC031087-1|AAH31087.1| 465|Homo sapiens gamma-aminobutyric acid... 36 0.19
>AJ306454-1|CAC34819.1| 497|Homo sapiens neuronal nicotinic
acetylcholine receptor beta-4 subunit protein.
Length = 497
Score = 61.7 bits (143), Expect = 3e-09
Identities = 41/158 (25%), Positives = 71/158 (44%), Gaps = 8/158 (5%)
Frame = +2
Query: 92 AIASAAECENATSLSLMIDSLL--ATYDRESPP--DSKIVVNLTLHLRHA---NIRESES 250
A+ C A + ++D LL Y+ P S ++++ L L A ++ E E
Sbjct: 14 ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQ 73
Query: 251 TVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPNVVLLNAAATTAGDYALRAR 427
+ L+ W D RL+WN+ + G + + ++R+W P++VL N T
Sbjct: 74 IMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNDGTYEVSVYTNLI 133
Query: 428 VSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFXVR 541
V +NGSV W+ + +++ +P D Q CT R
Sbjct: 134 VRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFR 171
>Y08416-1|CAA69693.1| 498|Homo sapiens nicotinic acetylcholine
receptor beta4 subunit precursor protein.
Length = 498
Score = 59.7 bits (138), Expect = 1e-08
Identities = 42/159 (26%), Positives = 72/159 (45%), Gaps = 9/159 (5%)
Frame = +2
Query: 92 AIASAAECENATSLSLMIDSLL--ATYDRESPP--DSKIVVNLTLHLRHA---NIRESES 250
A+ C A + ++D LL Y+ P S ++++ L L A ++ E E
Sbjct: 14 ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQ 73
Query: 251 TVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPNVVLLNAA-ATTAGDYALRA 424
+ L+ W D RL+WN+ + G + + ++R+W P++VL N A T
Sbjct: 74 IMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNADGTYEVSVYTNL 133
Query: 425 RVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFXVR 541
V +NGSV W+ + +++ +P D Q CT R
Sbjct: 134 IVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFR 172
>U62439-1|AAB40117.1| 498|Homo sapiens nicotinic acetylcholine
receptor beta4 subunit precursor protein.
Length = 498
Score = 59.7 bits (138), Expect = 1e-08
Identities = 42/159 (26%), Positives = 72/159 (45%), Gaps = 9/159 (5%)
Frame = +2
Query: 92 AIASAAECENATSLSLMIDSLL--ATYDRESPP--DSKIVVNLTLHLRHA---NIRESES 250
A+ C A + ++D LL Y+ P S ++++ L L A ++ E E
Sbjct: 14 ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQ 73
Query: 251 TVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPNVVLLNAA-ATTAGDYALRA 424
+ L+ W D RL+WN+ + G + + ++R+W P++VL N A T
Sbjct: 74 IMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNADGTYEVSVYTNL 133
Query: 425 RVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFXVR 541
V +NGSV W+ + +++ +P D Q CT R
Sbjct: 134 IVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFR 172
>U48861-1|AAA92123.1| 498|Homo sapiens beta 4 nicotinic
acetylcholine receptor subunit protein.
Length = 498
Score = 59.7 bits (138), Expect = 1e-08
Identities = 42/159 (26%), Positives = 72/159 (45%), Gaps = 9/159 (5%)
Frame = +2
Query: 92 AIASAAECENATSLSLMIDSLL--ATYDRESPP--DSKIVVNLTLHLRHA---NIRESES 250
A+ C A + ++D LL Y+ P S ++++ L L A ++ E E
Sbjct: 14 ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQ 73
Query: 251 TVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPNVVLLNAA-ATTAGDYALRA 424
+ L+ W D RL+WN+ + G + + ++R+W P++VL N A T
Sbjct: 74 IMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNADGTYEVSVYTNL 133
Query: 425 RVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFXVR 541
V +NGSV W+ + +++ +P D Q CT R
Sbjct: 134 IVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFR 172
>BC096082-1|AAH96082.1| 498|Homo sapiens cholinergic receptor,
nicotinic, beta 4 protein.
Length = 498
Score = 59.7 bits (138), Expect = 1e-08
Identities = 42/159 (26%), Positives = 72/159 (45%), Gaps = 9/159 (5%)
Frame = +2
Query: 92 AIASAAECENATSLSLMIDSLL--ATYDRESPP--DSKIVVNLTLHLRHA---NIRESES 250
A+ C A + ++D LL Y+ P S ++++ L L A ++ E E
Sbjct: 14 ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQ 73
Query: 251 TVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPNVVLLNAA-ATTAGDYALRA 424
+ L+ W D RL+WN+ + G + + ++R+W P++VL N A T
Sbjct: 74 IMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNADGTYEVSVYTNL 133
Query: 425 RVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFXVR 541
V +NGSV W+ + +++ +P D Q CT R
Sbjct: 134 IVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFR 172
>BC096080-1|AAH96080.1| 498|Homo sapiens cholinergic receptor,
nicotinic, beta 4 protein.
Length = 498
Score = 59.7 bits (138), Expect = 1e-08
Identities = 42/159 (26%), Positives = 72/159 (45%), Gaps = 9/159 (5%)
Frame = +2
Query: 92 AIASAAECENATSLSLMIDSLL--ATYDRESPP--DSKIVVNLTLHLRHA---NIRESES 250
A+ C A + ++D LL Y+ P S ++++ L L A ++ E E
Sbjct: 14 ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQ 73
Query: 251 TVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPNVVLLNAA-ATTAGDYALRA 424
+ L+ W D RL+WN+ + G + + ++R+W P++VL N A T
Sbjct: 74 IMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNADGTYEVSVYTNL 133
Query: 425 RVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFXVR 541
V +NGSV W+ + +++ +P D Q CT R
Sbjct: 134 IVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFR 172
>AF306329-1|AAL02062.1| 498|Homo sapiens neuronal nicotinic
acetylcholine receptor beta 4 subunit protein.
Length = 498
Score = 59.7 bits (138), Expect = 1e-08
Identities = 42/159 (26%), Positives = 72/159 (45%), Gaps = 9/159 (5%)
Frame = +2
Query: 92 AIASAAECENATSLSLMIDSLL--ATYDRESPP--DSKIVVNLTLHLRHA---NIRESES 250
A+ C A + ++D LL Y+ P S ++++ L L A ++ E E
Sbjct: 14 ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQ 73
Query: 251 TVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPNVVLLNAA-ATTAGDYALRA 424
+ L+ W D RL+WN+ + G + + ++R+W P++VL N A T
Sbjct: 74 IMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNADGTYEVSVYTNL 133
Query: 425 RVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFXVR 541
V +NGSV W+ + +++ +P D Q CT R
Sbjct: 134 IVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFR 172
>X68275-1|CAA48336.1| 451|Homo sapiens nicotinic receptor beta 4
subunit protein.
Length = 451
Score = 55.6 bits (128), Expect = 2e-07
Identities = 33/119 (27%), Positives = 56/119 (47%), Gaps = 3/119 (2%)
Frame = +2
Query: 194 IVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 367
I + L L L ++ E + + L+ W D RL+WN+ + G + + ++R+W P
Sbjct: 7 ISIKLQLSLAQLISVNERDEIMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLP 66
Query: 368 NVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFXVR 541
++VL N A T V +NGSV W+ + +++ +P D Q CT R
Sbjct: 67 DIVLYNNADGTYEVSVYTNLIVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFR 125
>X14830-1|CAA32939.1| 501|Homo sapiens protein ( Human mRNA for
muscle acetylcholine receptor beta-subunit. ).
Length = 501
Score = 55.6 bits (128), Expect = 2e-07
Identities = 42/124 (33%), Positives = 63/124 (50%), Gaps = 4/124 (3%)
Frame = +2
Query: 170 RESPPDSKIVVNLTL-HLRHANIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLV 343
RE ++ V L L L N ++ E + ++ DL+ W D RLSW+ E G + +
Sbjct: 46 REVGDRVRVSVGLILAQLISLNEKDEEMSTKVYLDLE--WTDYRLSWDPAEHDGIDSLRI 103
Query: 344 SSERLWRPNVVLLNAAATTAGDYAL--RARVSNNGSVSWIKRLDISTPISMQLDNWPNDM 517
++E +W P+VVLLN D AL VS++GSV W + S+Q+ +P D
Sbjct: 104 TAESVWLPDVVLLNNNDGNF-DVALDISVVVSSDGSVRWQPPGIYRSSCSIQVTYFPFDW 162
Query: 518 QTCT 529
Q CT
Sbjct: 163 QNCT 166
>BC011371-1|AAH11371.1| 501|Homo sapiens cholinergic receptor,
nicotinic, beta 1 (muscle) protein.
Length = 501
Score = 55.6 bits (128), Expect = 2e-07
Identities = 42/124 (33%), Positives = 63/124 (50%), Gaps = 4/124 (3%)
Frame = +2
Query: 170 RESPPDSKIVVNLTL-HLRHANIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLV 343
RE ++ V L L L N ++ E + ++ DL+ W D RLSW+ E G + +
Sbjct: 46 REVGDRVRVSVGLILAQLISLNEKDEEMSTKVYLDLE--WTDYRLSWDPAEHDGIDSLRI 103
Query: 344 SSERLWRPNVVLLNAAATTAGDYAL--RARVSNNGSVSWIKRLDISTPISMQLDNWPNDM 517
++E +W P+VVLLN D AL VS++GSV W + S+Q+ +P D
Sbjct: 104 TAESVWLPDVVLLNNNDGNF-DVALDISVVVSSDGSVRWQPPGIYRSSCSIQVTYFPFDW 162
Query: 518 QTCT 529
Q CT
Sbjct: 163 QNCT 166
>BC023553-1|AAH23553.1| 501|Homo sapiens cholinergic receptor,
nicotinic, beta 1 (muscle) protein.
Length = 501
Score = 54.4 bits (125), Expect = 5e-07
Identities = 40/126 (31%), Positives = 64/126 (50%), Gaps = 6/126 (4%)
Frame = +2
Query: 170 RESPPDSKIVVNLTL-HLRHANIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLV 343
RE ++ V L L L N ++ E + ++ DL+ W D RLSW+ E G + +
Sbjct: 46 REVGDRVRVSVGLILAQLISLNEKDEEMSTKVYLDLE--WTDYRLSWDPAEHDGIDSLRI 103
Query: 344 SSERLWRPNVVLLNAAATTAGDY----ALRARVSNNGSVSWIKRLDISTPISMQLDNWPN 511
++E +W P+VVLLN G++ + VS++GSV W + S+Q+ +P
Sbjct: 104 TAESVWLPDVVLLN---NNDGNFYVALDISVVVSSDGSVRWQPPGIYRSSCSIQVTYFPF 160
Query: 512 DMQTCT 529
D Q CT
Sbjct: 161 DWQNCT 166
>Y08417-1|CAA69694.1| 458|Homo sapiens nicotinic acetylcholine
receptor beta3 subunit precursor protein.
Length = 458
Score = 53.6 bits (123), Expect = 9e-07
Identities = 28/88 (31%), Positives = 43/88 (48%), Gaps = 2/88 (2%)
Frame = +2
Query: 272 LQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPNVVLL-NAAATTAGDYALRARVSNNGS 445
L+ W D +L WN ++G + V SE LW P++VL NA G + V +NG+
Sbjct: 81 LKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFEGSLMTKVIVKSNGT 140
Query: 446 VSWIKRLDISTPISMQLDNWPNDMQTCT 529
V W + +M + +P D Q C+
Sbjct: 141 VVWTPPASYKSSCTMDVTFFPFDRQNCS 168
>X67513-1|CAA47851.1| 423|Homo sapiens nicotinic acetylcholine
receptor beta-3 subunit protein.
Length = 423
Score = 53.6 bits (123), Expect = 9e-07
Identities = 28/88 (31%), Positives = 43/88 (48%), Gaps = 2/88 (2%)
Frame = +2
Query: 272 LQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPNVVLL-NAAATTAGDYALRARVSNNGS 445
L+ W D +L WN ++G + V SE LW P++VL NA G + V +NG+
Sbjct: 46 LKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFEGSLMTKVIVKSNGT 105
Query: 446 VSWIKRLDISTPISMQLDNWPNDMQTCT 529
V W + +M + +P D Q C+
Sbjct: 106 VVWTPPASYKSSCTMDVTFFPFDRQNCS 133
>U62438-1|AAB40116.1| 458|Homo sapiens nicotinic acetylcholine
receptor beta3 subunit precursor protein.
Length = 458
Score = 53.6 bits (123), Expect = 9e-07
Identities = 28/88 (31%), Positives = 43/88 (48%), Gaps = 2/88 (2%)
Frame = +2
Query: 272 LQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPNVVLL-NAAATTAGDYALRARVSNNGS 445
L+ W D +L WN ++G + V SE LW P++VL NA G + V +NG+
Sbjct: 81 LKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFEGSLMTKVIVKSNGT 140
Query: 446 VSWIKRLDISTPISMQLDNWPNDMQTCT 529
V W + +M + +P D Q C+
Sbjct: 141 VVWTPPASYKSSCTMDVTFFPFDRQNCS 168
>BC069788-1|AAH69788.1| 458|Homo sapiens cholinergic receptor,
nicotinic, beta 3 protein.
Length = 458
Score = 53.6 bits (123), Expect = 9e-07
Identities = 28/88 (31%), Positives = 43/88 (48%), Gaps = 2/88 (2%)
Frame = +2
Query: 272 LQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPNVVLL-NAAATTAGDYALRARVSNNGS 445
L+ W D +L WN ++G + V SE LW P++VL NA G + V +NG+
Sbjct: 81 LKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFEGSLMTKVIVKSNGT 140
Query: 446 VSWIKRLDISTPISMQLDNWPNDMQTCT 529
V W + +M + +P D Q C+
Sbjct: 141 VVWTPPASYKSSCTMDVTFFPFDRQNCS 168
>BC069703-1|AAH69703.1| 458|Homo sapiens cholinergic receptor,
nicotinic, beta 3 protein.
Length = 458
Score = 53.6 bits (123), Expect = 9e-07
Identities = 28/88 (31%), Positives = 43/88 (48%), Gaps = 2/88 (2%)
Frame = +2
Query: 272 LQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPNVVLL-NAAATTAGDYALRARVSNNGS 445
L+ W D +L WN ++G + V SE LW P++VL NA G + V +NG+
Sbjct: 81 LKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFEGSLMTKVIVKSNGT 140
Query: 446 VSWIKRLDISTPISMQLDNWPNDMQTCT 529
V W + +M + +P D Q C+
Sbjct: 141 VVWTPPASYKSSCTMDVTFFPFDRQNCS 168
>BC069681-1|AAH69681.1| 458|Homo sapiens cholinergic receptor,
nicotinic, beta 3 protein.
Length = 458
Score = 53.6 bits (123), Expect = 9e-07
Identities = 28/88 (31%), Positives = 43/88 (48%), Gaps = 2/88 (2%)
Frame = +2
Query: 272 LQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPNVVLL-NAAATTAGDYALRARVSNNGS 445
L+ W D +L WN ++G + V SE LW P++VL NA G + V +NG+
Sbjct: 81 LKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFEGSLMTKVIVKSNGT 140
Query: 446 VSWIKRLDISTPISMQLDNWPNDMQTCT 529
V W + +M + +P D Q C+
Sbjct: 141 VVWTPPASYKSSCTMDVTFFPFDRQNCS 168
>AF140765-1|AAD33063.1| 458|Homo sapiens neuronal acetylcholine
receptor beta-3 subunit precursor protein.
Length = 458
Score = 53.6 bits (123), Expect = 9e-07
Identities = 28/88 (31%), Positives = 43/88 (48%), Gaps = 2/88 (2%)
Frame = +2
Query: 272 LQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPNVVLL-NAAATTAGDYALRARVSNNGS 445
L+ W D +L WN ++G + V SE LW P++VL NA G + V +NG+
Sbjct: 81 LKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFEGSLMTKVIVKSNGT 140
Query: 446 VSWIKRLDISTPISMQLDNWPNDMQTCT 529
V W + +M + +P D Q C+
Sbjct: 141 VVWTPPASYKSSCTMDVTFFPFDRQNCS 168
>M86383-1|AAC84176.1| 502|Homo sapiens nicotinic acetylcholine
receptor alpha 3 subunit precursor protein.
Length = 502
Score = 53.2 bits (122), Expect = 1e-06
Identities = 41/172 (23%), Positives = 77/172 (44%), Gaps = 6/172 (3%)
Frame = +2
Query: 32 SVVIKCRRLILFCYRFLLTCAIASAAECENATSLSLMIDSLLATYDRESPPDSKIVVNLT 211
S+ + CR +L LL A AS AE L + ++ S P ++++
Sbjct: 6 SLPLACRARLLLLLLSLLPVARASEAEHRLFERLFEDYNEIIRPVANVSDP---VIIHFE 62
Query: 212 LHLRH-ANIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPNVVLLN 385
+ + + E + L+ W D +L WN +G + ++ V ++++W+P++VL N
Sbjct: 63 VSMSQLVKVDEVNQIMETNLWLKQIWNDYKLKWNPSGYGGAEFMRVPAQKIWKPDIVLYN 122
Query: 386 AAATTAGDYAL----RARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCT 529
A GD+ + +A + G V+WI + + + +P D Q CT
Sbjct: 123 NAV---GDFQVTTKTKALLKYTGEVTWIPPAIFKSSCKIDVTYFPFDYQNCT 171
>BT006897-1|AAP35543.1| 505|Homo sapiens cholinergic receptor,
nicotinic, alpha polypeptide 3 protein.
Length = 505
Score = 53.2 bits (122), Expect = 1e-06
Identities = 39/162 (24%), Positives = 72/162 (44%), Gaps = 3/162 (1%)
Frame = +2
Query: 53 RLILFCYRFLLTCAIASAAECENATSLSLMIDSLLATYDRESPPDSKIVVNLTLHLRH-A 229
RL+L LL A AS AE L + ++ S P ++++ + +
Sbjct: 16 RLLLLLLLSLLPVARASEAEHRLFERLFEDYNEIIRPVANVSDP---VIIHFEVSMSQLV 72
Query: 230 NIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPNVVLLN-AAATTA 403
+ E + L+ W D +L WN ++G + ++ V ++++W+P++VL N A
Sbjct: 73 KVDEVNQIMETNLWLKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQ 132
Query: 404 GDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCT 529
D +A + G V+WI + + + +P D Q CT
Sbjct: 133 VDDKTKALLKYTGEVTWIPPAIFKSSCKIDVTYFPFDYQNCT 174
>BT006646-1|AAP35292.1| 489|Homo sapiens cholinergic receptor,
nicotinic, alpha polypeptide 3 protein.
Length = 489
Score = 53.2 bits (122), Expect = 1e-06
Identities = 39/162 (24%), Positives = 72/162 (44%), Gaps = 3/162 (1%)
Frame = +2
Query: 53 RLILFCYRFLLTCAIASAAECENATSLSLMIDSLLATYDRESPPDSKIVVNLTLHLRH-A 229
RL+L LL A AS AE L + ++ S P ++++ + +
Sbjct: 16 RLLLLLLLSLLPVARASEAEHRLFERLFEDYNEIIRPVANVSDP---VIIHFEVSMSQLV 72
Query: 230 NIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPNVVLLN-AAATTA 403
+ E + L+ W D +L WN ++G + ++ V ++++W+P++VL N A
Sbjct: 73 KVDEVNQIMETNLWLKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQ 132
Query: 404 GDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCT 529
D +A + G V+WI + + + +P D Q CT
Sbjct: 133 VDDKTKALLKYTGEVTWIPPAIFKSSCKIDVTYFPFDYQNCT 174
>BC006114-1|AAH06114.1| 489|Homo sapiens CHRNA3 protein protein.
Length = 489
Score = 53.2 bits (122), Expect = 1e-06
Identities = 39/162 (24%), Positives = 72/162 (44%), Gaps = 3/162 (1%)
Frame = +2
Query: 53 RLILFCYRFLLTCAIASAAECENATSLSLMIDSLLATYDRESPPDSKIVVNLTLHLRH-A 229
RL+L LL A AS AE L + ++ S P ++++ + +
Sbjct: 16 RLLLLLLLSLLPVARASEAEHRLFERLFEDYNEIIRPVANVSDP---VIIHFEVSMSQLV 72
Query: 230 NIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPNVVLLN-AAATTA 403
+ E + L+ W D +L WN ++G + ++ V ++++W+P++VL N A
Sbjct: 73 KVDEVNQIMETNLWLKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQ 132
Query: 404 GDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCT 529
D +A + G V+WI + + + +P D Q CT
Sbjct: 133 VDDKTKALLKYTGEVTWIPPAIFKSSCKIDVTYFPFDYQNCT 174
>BC002996-1|AAH02996.1| 505|Homo sapiens cholinergic receptor,
nicotinic, alpha 3 protein.
Length = 505
Score = 53.2 bits (122), Expect = 1e-06
Identities = 39/162 (24%), Positives = 72/162 (44%), Gaps = 3/162 (1%)
Frame = +2
Query: 53 RLILFCYRFLLTCAIASAAECENATSLSLMIDSLLATYDRESPPDSKIVVNLTLHLRH-A 229
RL+L LL A AS AE L + ++ S P ++++ + +
Sbjct: 16 RLLLLLLLSLLPVARASEAEHRLFERLFEDYNEIIRPVANVSDP---VIIHFEVSMSQLV 72
Query: 230 NIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPNVVLLN-AAATTA 403
+ E + L+ W D +L WN ++G + ++ V ++++W+P++VL N A
Sbjct: 73 KVDEVNQIMETNLWLKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQ 132
Query: 404 GDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCT 529
D +A + G V+WI + + + +P D Q CT
Sbjct: 133 VDDKTKALLKYTGEVTWIPPAIFKSSCKIDVTYFPFDYQNCT 174
>BC001642-1|AAH01642.1| 505|Homo sapiens cholinergic receptor,
nicotinic, alpha 3 protein.
Length = 505
Score = 53.2 bits (122), Expect = 1e-06
Identities = 39/162 (24%), Positives = 72/162 (44%), Gaps = 3/162 (1%)
Frame = +2
Query: 53 RLILFCYRFLLTCAIASAAECENATSLSLMIDSLLATYDRESPPDSKIVVNLTLHLRH-A 229
RL+L LL A AS AE L + ++ S P ++++ + +
Sbjct: 16 RLLLLLLLSLLPVARASEAEHRLFERLFEDYNEIIRPVANVSDP---VIIHFEVSMSQLV 72
Query: 230 NIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPNVVLLN-AAATTA 403
+ E + L+ W D +L WN ++G + ++ V ++++W+P++VL N A
Sbjct: 73 KVDEVNQIMETNLWLKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQ 132
Query: 404 GDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCT 529
D +A + G V+WI + + + +P D Q CT
Sbjct: 133 VDDKTKALLKYTGEVTWIPPAIFKSSCKIDVTYFPFDYQNCT 174
>BC000513-1|AAH00513.1| 505|Homo sapiens cholinergic receptor,
nicotinic, alpha 3 protein.
Length = 505
Score = 53.2 bits (122), Expect = 1e-06
Identities = 39/162 (24%), Positives = 72/162 (44%), Gaps = 3/162 (1%)
Frame = +2
Query: 53 RLILFCYRFLLTCAIASAAECENATSLSLMIDSLLATYDRESPPDSKIVVNLTLHLRH-A 229
RL+L LL A AS AE L + ++ S P ++++ + +
Sbjct: 16 RLLLLLLLSLLPVARASEAEHRLFERLFEDYNEIIRPVANVSDP---VIIHFEVSMSQLV 72
Query: 230 NIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPNVVLLN-AAATTA 403
+ E + L+ W D +L WN ++G + ++ V ++++W+P++VL N A
Sbjct: 73 KVDEVNQIMETNLWLKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQ 132
Query: 404 GDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCT 529
D +A + G V+WI + + + +P D Q CT
Sbjct: 133 VDDKTKALLKYTGEVTWIPPAIFKSSCKIDVTYFPFDYQNCT 174
>AF385584-1|AAK68110.1| 489|Homo sapiens nicotinic cholinergic
receptor alpha 3 protein.
Length = 489
Score = 53.2 bits (122), Expect = 1e-06
Identities = 39/162 (24%), Positives = 72/162 (44%), Gaps = 3/162 (1%)
Frame = +2
Query: 53 RLILFCYRFLLTCAIASAAECENATSLSLMIDSLLATYDRESPPDSKIVVNLTLHLRH-A 229
RL+L LL A AS AE L + ++ S P ++++ + +
Sbjct: 10 RLLLLLLLSLLPVARASEAEHRLFERLFEDYNEIIRPVANVSDP---VIIHFEVSMSQLV 66
Query: 230 NIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPNVVLLN-AAATTA 403
+ E + L+ W D +L WN ++G + ++ V ++++W+P++VL N A
Sbjct: 67 KVDEVNQIMETNLWLKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQ 126
Query: 404 GDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCT 529
D +A + G V+WI + + + +P D Q CT
Sbjct: 127 VDDKTKALLKYTGEVTWIPPAIFKSSCKIDVTYFPFDYQNCT 168
>Y16281-1|CAA76154.1| 529|Homo sapiens nicotinic acetylcholine
receptor alpha2 subunit precursor protein.
Length = 529
Score = 52.0 bits (119), Expect = 3e-06
Identities = 28/87 (32%), Positives = 45/87 (51%), Gaps = 2/87 (2%)
Frame = +2
Query: 272 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPNVVLLNAA-ATTAGDYALRARVSNNGS 445
L+ W D +L WN ++G T L V SE +W P++VL N A A + +A + + G+
Sbjct: 111 LKQEWSDYKLRWNPADFGNITSLRVPSEMIWIPDIVLYNNADGEFAVTHMTKAHLFSTGT 170
Query: 446 VSWIKRLDISTPISMQLDNWPNDMQTC 526
V W+ + S+ + +P D Q C
Sbjct: 171 VHWVPPAIYKSSCSIDVTFFPFDQQNC 197
>Y00762-1|CAA68731.1| 457|Homo sapiens protein ( Human mRNA for
muscle acetylcholine receptor alpha-subunit. ).
Length = 457
Score = 52.0 bits (119), Expect = 3e-06
Identities = 40/160 (25%), Positives = 73/160 (45%), Gaps = 10/160 (6%)
Frame = +2
Query: 80 LLTCAIASAAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHA---NIRES 244
LL ++ SA + + ++ L Y P D + VV +T+ L+ N+ E
Sbjct: 7 LLLFSLCSAGLVLGSEHETRLVAKLFKDYSSVVRPVEDHRQVVEVTVGLQLIQLINVDEV 66
Query: 245 ESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPNVVLLNAAATTAGDYAL- 418
V L+ W+D L WN ++G + + SE++WRP++VL N A GD+A+
Sbjct: 67 NQIVTTNVRLKQQWVDYNLKWNPDDYGGVKKIHIPSEKIWRPDLVLYNNA---DGDFAIV 123
Query: 419 ---RARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCT 529
+ + G ++W + + + ++P D Q C+
Sbjct: 124 KFTKVLLQYTGHITWTPPAIFKSYCEIIVTHFPFDEQNCS 163
>X02502-1|CAA26344.1| 457|Homo sapiens acetylcholine receptor
protein.
Length = 457
Score = 52.0 bits (119), Expect = 3e-06
Identities = 40/160 (25%), Positives = 73/160 (45%), Gaps = 10/160 (6%)
Frame = +2
Query: 80 LLTCAIASAAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHA---NIRES 244
LL ++ SA + + ++ L Y P D + VV +T+ L+ N+ E
Sbjct: 7 LLLFSLCSAGLVLGSEHETRLVAKLFKDYSSVVRPVEDHRQVVEVTVGLQLIQLINVDEV 66
Query: 245 ESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPNVVLLNAAATTAGDYAL- 418
V L+ W+D L WN ++G + + SE++WRP++VL N A GD+A+
Sbjct: 67 NQIVTTNVRLKQQWVDYNLKWNPDDYGGVKKIHIPSEKIWRPDLVLYNNA---DGDFAIV 123
Query: 419 ---RARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCT 529
+ + G ++W + + + ++P D Q C+
Sbjct: 124 KFTKVLLQYTGHITWTPPAIFKSYCEIIVTHFPFDEQNCS 163
>U62431-1|AAB40109.1| 529|Homo sapiens nicotinic acetylcholine
receptor alpha2 subunit precursor protein.
Length = 529
Score = 52.0 bits (119), Expect = 3e-06
Identities = 28/87 (32%), Positives = 45/87 (51%), Gaps = 2/87 (2%)
Frame = +2
Query: 272 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPNVVLLNAA-ATTAGDYALRARVSNNGS 445
L+ W D +L WN ++G T L V SE +W P++VL N A A + +A + + G+
Sbjct: 111 LKQEWSDYKLRWNPADFGNITSLRVPSEMIWIPDIVLYNNADGEFAVTHMTKAHLFSTGT 170
Query: 446 VSWIKRLDISTPISMQLDNWPNDMQTC 526
V W+ + S+ + +P D Q C
Sbjct: 171 VHWVPPAIYKSSCSIDVTFFPFDQQNC 197
>S77094-1|AAD14247.1| 457|Homo sapiens nicotinic acetylcholine
receptor alpha subunit|AChR protein.
Length = 457
Score = 52.0 bits (119), Expect = 3e-06
Identities = 40/160 (25%), Positives = 73/160 (45%), Gaps = 10/160 (6%)
Frame = +2
Query: 80 LLTCAIASAAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHA---NIRES 244
LL ++ SA + + ++ L Y P D + VV +T+ L+ N+ E
Sbjct: 7 LLLFSLCSAGLVLGSEHETRLVAKLFKDYSSVVRPVEDHRQVVEVTVGLQLIQLINVDEV 66
Query: 245 ESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPNVVLLNAAATTAGDYAL- 418
V L+ W+D L WN ++G + + SE++WRP++VL N A GD+A+
Sbjct: 67 NQIVTTNVRLKQQWVDYNLKWNPDDYGGVKKIHIPSEKIWRPDLVLYNNA---DGDFAIV 123
Query: 419 ---RARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCT 529
+ + G ++W + + + ++P D Q C+
Sbjct: 124 KFTKVLLQYTGHITWTPPAIFKSYCEIIVTHFPFDEQNCS 163
>BC006314-1|AAH06314.1| 269|Homo sapiens CHRNA1 protein protein.
Length = 269
Score = 52.0 bits (119), Expect = 3e-06
Identities = 40/160 (25%), Positives = 73/160 (45%), Gaps = 10/160 (6%)
Frame = +2
Query: 80 LLTCAIASAAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHA---NIRES 244
LL ++ SA + + ++ L Y P D + VV +T+ L+ N+ E
Sbjct: 7 LLLFSLCSAGLVLGSEHETRLVAKLFKDYSSVVRPVEDHRQVVEVTVGLQLIQLINVDEV 66
Query: 245 ESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPNVVLLNAAATTAGDYAL- 418
V L+ W+D L WN ++G + + SE++WRP++VL N A GD+A+
Sbjct: 67 NQIVTTNVRLKQQWVDYNLKWNPDDYGGVKKIHIPSEKIWRPDLVLYNNA---DGDFAIV 123
Query: 419 ---RARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCT 529
+ + G ++W + + + ++P D Q C+
Sbjct: 124 KFTKVLLQYTGHITWTPPAIFKSYCEIIVTHFPFDEQNCS 163
>AC018890-1|AAY14687.1| 457|Homo sapiens unknown protein.
Length = 457
Score = 52.0 bits (119), Expect = 3e-06
Identities = 40/160 (25%), Positives = 73/160 (45%), Gaps = 10/160 (6%)
Frame = +2
Query: 80 LLTCAIASAAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHA---NIRES 244
LL ++ SA + + ++ L Y P D + VV +T+ L+ N+ E
Sbjct: 7 LLLFSLCSAGLVLGSEHETRLVAKLFKDYSSVVRPVEDHRQVVEVTVGLQLIQLINVDEV 66
Query: 245 ESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPNVVLLNAAATTAGDYAL- 418
V L+ W+D L WN ++G + + SE++WRP++VL N A GD+A+
Sbjct: 67 NQIVTTNVRLKQQWVDYNLKWNPDDYGGVKKIHIPSEKIWRPDLVLYNNA---DGDFAIV 123
Query: 419 ---RARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCT 529
+ + G ++W + + + ++P D Q C+
Sbjct: 124 KFTKVLLQYTGHITWTPPAIFKSYCEIIVTHFPFDEQNCS 163
>Y08418-1|CAA69695.1| 503|Homo sapiens nicotinic acetylcholine
receptor alpha3 subunit precursor protein.
Length = 503
Score = 51.6 bits (118), Expect = 4e-06
Identities = 25/88 (28%), Positives = 46/88 (52%), Gaps = 2/88 (2%)
Frame = +2
Query: 272 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPNVVLLN-AAATTAGDYALRARVSNNGS 445
L+ W D +L WN ++G + ++ V ++++W+P++VL N A D +A + G
Sbjct: 85 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 144
Query: 446 VSWIKRLDISTPISMQLDNWPNDMQTCT 529
V+WI + + + +P D Q CT
Sbjct: 145 VTWIPPAIFKSSCKIDVTYFPFDYQNCT 172
>X66403-1|CAA47030.1| 493|Homo sapiens acetylcholine receptor
epsilon subunit CHRNE protein.
Length = 493
Score = 51.6 bits (118), Expect = 4e-06
Identities = 32/123 (26%), Positives = 60/123 (48%), Gaps = 3/123 (2%)
Frame = +2
Query: 182 PDSKIVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEWG-CSTWLVSSER 355
P+ + ++L + L + ++ E E T+ + ++W D RL+++ ++G T V SE
Sbjct: 45 PEDTVTISLKVTLTNLISLNEKEETLTTSVWIGIDWQDYRLNYSKDDFGGIETLRVPSEL 104
Query: 356 LWRPNVVLLNAAATTAG-DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTF 532
+W P +VL N G Y V GSV+W+ + ++++ +P D Q C+
Sbjct: 105 VWLPEIVLENNIDGQFGVAYDANVLVYEGGSVTWLPPAIYRSVCAVEVTYFPFDWQNCSL 164
Query: 533 XVR 541
R
Sbjct: 165 IFR 167
>X53559-1|CAA37625.1| 474|Homo sapiens neuronal nicotinic
acetylcholine receptor alpha-3merase protein.
Length = 474
Score = 51.6 bits (118), Expect = 4e-06
Identities = 25/88 (28%), Positives = 46/88 (52%), Gaps = 2/88 (2%)
Frame = +2
Query: 272 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPNVVLLN-AAATTAGDYALRARVSNNGS 445
L+ W D +L WN ++G + ++ V ++++W+P++VL N A D +A + G
Sbjct: 56 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 115
Query: 446 VSWIKRLDISTPISMQLDNWPNDMQTCT 529
V+WI + + + +P D Q CT
Sbjct: 116 VTWIPPAIFKSSCKIDVTYFPFDYQNCT 143
>U62432-1|AAB40110.1| 504|Homo sapiens nicotinic acetylcholine
receptor alpha3 subunit precursor protein.
Length = 504
Score = 51.6 bits (118), Expect = 4e-06
Identities = 25/88 (28%), Positives = 46/88 (52%), Gaps = 2/88 (2%)
Frame = +2
Query: 272 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPNVVLLN-AAATTAGDYALRARVSNNGS 445
L+ W D +L WN ++G + ++ V ++++W+P++VL N A D +A + G
Sbjct: 86 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 145
Query: 446 VSWIKRLDISTPISMQLDNWPNDMQTCT 529
V+WI + + + +P D Q CT
Sbjct: 146 VTWIPPAIFKSSCKIDVTYFPFDYQNCT 173
>M37981-1|AAA59942.1| 503|Homo sapiens neuronal nicotinic
acetylcholine receptor protein.
Length = 503
Score = 51.6 bits (118), Expect = 4e-06
Identities = 25/88 (28%), Positives = 46/88 (52%), Gaps = 2/88 (2%)
Frame = +2
Query: 272 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPNVVLLN-AAATTAGDYALRARVSNNGS 445
L+ W D +L WN ++G + ++ V ++++W+P++VL N A D +A + G
Sbjct: 85 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 144
Query: 446 VSWIKRLDISTPISMQLDNWPNDMQTCT 529
V+WI + + + +P D Q CT
Sbjct: 145 VTWIPPAIFKSSCKIDVTYFPFDYQNCT 172
>BC098443-1|AAH98443.1| 504|Homo sapiens cholinergic receptor,
nicotinic, alpha 3 protein.
Length = 504
Score = 51.6 bits (118), Expect = 4e-06
Identities = 25/88 (28%), Positives = 46/88 (52%), Gaps = 2/88 (2%)
Frame = +2
Query: 272 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPNVVLLN-AAATTAGDYALRARVSNNGS 445
L+ W D +L WN ++G + ++ V ++++W+P++VL N A D +A + G
Sbjct: 86 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 145
Query: 446 VSWIKRLDISTPISMQLDNWPNDMQTCT 529
V+WI + + + +P D Q CT
Sbjct: 146 VTWIPPAIFKSSCKIDVTYFPFDYQNCT 173
>AJ007783-1|CAA07682.1| 504|Homo sapiens nicotinic acetylcholine
receptor alpha-3 subunit protein.
Length = 504
Score = 51.6 bits (118), Expect = 4e-06
Identities = 25/88 (28%), Positives = 46/88 (52%), Gaps = 2/88 (2%)
Frame = +2
Query: 272 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPNVVLLN-AAATTAGDYALRARVSNNGS 445
L+ W D +L WN ++G + ++ V ++++W+P++VL N A D +A + G
Sbjct: 86 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 145
Query: 446 VSWIKRLDISTPISMQLDNWPNDMQTCT 529
V+WI + + + +P D Q CT
Sbjct: 146 VTWIPPAIFKSSCKIDVTYFPFDYQNCT 173
>AF105999-1|AAD24503.1| 493|Homo sapiens acetylcholine receptor
epsilon subunit protein.
Length = 493
Score = 51.6 bits (118), Expect = 4e-06
Identities = 32/123 (26%), Positives = 60/123 (48%), Gaps = 3/123 (2%)
Frame = +2
Query: 182 PDSKIVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEWG-CSTWLVSSER 355
P+ + ++L + L + ++ E E T+ + ++W D RL+++ ++G T V SE
Sbjct: 45 PEDTVTISLKVTLTNLISLNEKEETLTTSVWIGIDWQDYRLNYSKDDFGGIETLRVPSEL 104
Query: 356 LWRPNVVLLNAAATTAG-DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTF 532
+W P +VL N G Y V GSV+W+ + ++++ +P D Q C+
Sbjct: 105 VWLPEIVLENNIDGQFGVAYDANVLVYEGGSVTWLPPAIYRSVCAVEVTYFPFDWQNCSL 164
Query: 533 XVR 541
R
Sbjct: 165 IFR 167
>Y08419-1|CAA69696.1| 468|Homo sapiens nicotinic acetylcholine
receptor alpha5 subunit precursor protein.
Length = 468
Score = 50.8 bits (116), Expect = 6e-06
Identities = 31/136 (22%), Positives = 62/136 (45%), Gaps = 6/136 (4%)
Frame = +2
Query: 140 MIDSLLATYDRESPP----DSKIVVNLTLHLRH-ANIRESESTVRILADLQMNWIDKRLS 304
++ L Y+R P + KI + L + ++ E + L+ WID +L
Sbjct: 50 LLKDLFQDYERWVRPVEHLNDKIKIKFGLAISQLVDVDEKNQLMTTNVWLKQEWIDVKLR 109
Query: 305 WNAGEWG-CSTWLVSSERLWRPNVVLLNAAATTAGDYALRARVSNNGSVSWIKRLDISTP 481
WN ++G V S+ +W P++VL + A + + + NG+V+W + +
Sbjct: 110 WNPDDYGGIKVIRVPSDSVWTPDIVLFDNADGRFEGTSTKTVIRYNGTVTWTPPANYKSS 169
Query: 482 ISMQLDNWPNDMQTCT 529
++ + +P D+Q C+
Sbjct: 170 CTIDVTFFPFDLQNCS 185
>U62434-1|AAB40112.1| 468|Homo sapiens nicotinic acetylcholine
receptor alpha5 subunit precursor protein.
Length = 468
Score = 50.8 bits (116), Expect = 6e-06
Identities = 31/136 (22%), Positives = 62/136 (45%), Gaps = 6/136 (4%)
Frame = +2
Query: 140 MIDSLLATYDRESPP----DSKIVVNLTLHLRH-ANIRESESTVRILADLQMNWIDKRLS 304
++ L Y+R P + KI + L + ++ E + L+ WID +L
Sbjct: 50 LLKDLFQDYERWVRPVEHLNDKIKIKFGLAISQLVDVDEKNQLMTTNVWLKQEWIDVKLR 109
Query: 305 WNAGEWG-CSTWLVSSERLWRPNVVLLNAAATTAGDYALRARVSNNGSVSWIKRLDISTP 481
WN ++G V S+ +W P++VL + A + + + NG+V+W + +
Sbjct: 110 WNPDDYGGIKVIRVPSDSVWTPDIVLFDNADGRFEGTSTKTVIRYNGTVTWTPPANYKSS 169
Query: 482 ISMQLDNWPNDMQTCT 529
++ + +P D+Q C+
Sbjct: 170 CTIDVTFFPFDLQNCS 185
>BC033639-1|AAH33639.1| 468|Homo sapiens cholinergic receptor,
nicotinic, alpha 5 protein.
Length = 468
Score = 50.8 bits (116), Expect = 6e-06
Identities = 31/136 (22%), Positives = 62/136 (45%), Gaps = 6/136 (4%)
Frame = +2
Query: 140 MIDSLLATYDRESPP----DSKIVVNLTLHLRH-ANIRESESTVRILADLQMNWIDKRLS 304
++ L Y+R P + KI + L + ++ E + L+ WID +L
Sbjct: 50 LLKDLFQDYERWVRPVEHLNDKIKIKFGLAISQLVDVDEKNQLMTTNVWLKQEWIDVKLR 109
Query: 305 WNAGEWG-CSTWLVSSERLWRPNVVLLNAAATTAGDYALRARVSNNGSVSWIKRLDISTP 481
WN ++G V S+ +W P++VL + A + + + NG+V+W + +
Sbjct: 110 WNPDDYGGIKVIRVPSDSVWTPDIVLFDNADGRFEGTSTKTVIRYNGTVTWTPPANYKSS 169
Query: 482 ISMQLDNWPNDMQTCT 529
++ + +P D+Q C+
Sbjct: 170 CTIDVTFFPFDLQNCS 185
>AJ306481-1|CAC34820.1| 468|Homo sapiens neuronal nicotinic
acetylcholine receptor alpha-5subunit protein.
Length = 468
Score = 50.8 bits (116), Expect = 6e-06
Identities = 31/136 (22%), Positives = 62/136 (45%), Gaps = 6/136 (4%)
Frame = +2
Query: 140 MIDSLLATYDRESPP----DSKIVVNLTLHLRH-ANIRESESTVRILADLQMNWIDKRLS 304
++ L Y+R P + KI + L + ++ E + L+ WID +L
Sbjct: 50 LLKDLFQDYERWVRPVEHLNDKIKIKFGLAISQLVDVDEKNQLMTTNVWLKQEWIDVKLR 109
Query: 305 WNAGEWG-CSTWLVSSERLWRPNVVLLNAAATTAGDYALRARVSNNGSVSWIKRLDISTP 481
WN ++G V S+ +W P++VL + A + + + NG+V+W + +
Sbjct: 110 WNPDDYGGIKVIRVPSDSVWTPDIVLFDNADGRFEGTSTKTVIRYNGTVTWTPPANYKSS 169
Query: 482 ISMQLDNWPNDMQTCT 529
++ + +P D+Q C+
Sbjct: 170 CTIDVTFFPFDLQNCS 185
>AJ001935-1|CAA05108.1| 504|Homo sapiens CHRNB2 protein.
Length = 504
Score = 50.0 bits (114), Expect = 1e-05
Identities = 42/165 (25%), Positives = 70/165 (42%), Gaps = 4/165 (2%)
Frame = +2
Query: 59 ILFCYRFLLTCAIASAAECENATSLSLMIDSLLATYDRESPPDSKIV-VNLTLHLRHA-N 232
+L + L C+ A+ E L+ S R + S++V V L + L +
Sbjct: 10 LLLGFGLLRLCSGVWGADTEERLVEHLLDPSRYNKLIRPATNGSELVTVQLMVSLAQLIS 69
Query: 233 IRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPNVVLLNAA-ATTAG 406
+ E E + L W D RL+W E+ + S+ +W P+VVL N A
Sbjct: 70 VHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLPDVVLYNNADGMYEV 129
Query: 407 DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFXVR 541
+ A VS +GS+ W+ + +++ ++P D Q CT R
Sbjct: 130 SFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFR 174
>Y16282-1|CAA76155.1| 494|Homo sapiens nicotinic acetylcholine
receptor alpha6 subunit precursor protein.
Length = 494
Score = 49.6 bits (113), Expect = 1e-05
Identities = 35/149 (23%), Positives = 67/149 (44%), Gaps = 10/149 (6%)
Frame = +2
Query: 113 CENATSLSLMIDSLLATYDRESPPDSKIVVNLTLHL-----RHANIRESESTVRILADLQ 277
C + + L + Y++ P + +T+H + AN+ E + L+
Sbjct: 28 CVGCATEERLFHKLFSHYNQFIRPVENVSDPVTVHFEVAITQLANVDEVNQIMETNLWLR 87
Query: 278 MNWIDKRLSWNAGEW-GCSTWLVSSERLWRPNVVLLNAAATTAGDYAL----RARVSNNG 442
W D +L W+ E+ G T V ++++W+P++VL N A GD+ + +A + NG
Sbjct: 88 HIWNDYKLRWDPMEYDGIETLRVPADKIWKPDIVLYNNAV---GDFQVEGKTKALLKYNG 144
Query: 443 SVSWIKRLDISTPISMQLDNWPNDMQTCT 529
++W + M + +P D Q C+
Sbjct: 145 MITWTPPAIFKSSCPMDITFFPFDHQNCS 173
>X01715-1|CAA25861.1| 520|Homo sapiens acetylcholine receptor gamma
chain precursor protein.
Length = 520
Score = 49.6 bits (113), Expect = 1e-05
Identities = 38/138 (27%), Positives = 63/138 (45%), Gaps = 8/138 (5%)
Frame = +2
Query: 140 MIDSLLATYDRESPPDSKI--VVNLTLHLRHANI---RESESTVRILADLQMNWIDKRLS 304
++ L+ YD P + VVN++L L N+ E E + ++M W D RL
Sbjct: 32 LLADLMQNYDPNLRPAERDSDVVNVSLKLTLTNLISLNEREEALTTNVWIEMQWCDYRLR 91
Query: 305 WNAGEW-GCSTWLVSSERLWRPNVVLLNAAATTAGDYAL--RARVSNNGSVSWIKRLDIS 475
W+ ++ G V S +WRP++VL N + AL VS +G + W+
Sbjct: 92 WDPRDYEGLWVLRVPSTMVWRPDIVLEN-NVDGVFEVALYCNVLVSPDGCIYWLPPAIFR 150
Query: 476 TPISMQLDNWPNDMQTCT 529
+ S+ + +P D Q C+
Sbjct: 151 SACSISVTYFPFDWQNCS 168
>U62435-1|AAB40113.1| 494|Homo sapiens nicotinic acetylcholine
receptor alpha6 subunit precursor protein.
Length = 494
Score = 49.6 bits (113), Expect = 1e-05
Identities = 35/149 (23%), Positives = 67/149 (44%), Gaps = 10/149 (6%)
Frame = +2
Query: 113 CENATSLSLMIDSLLATYDRESPPDSKIVVNLTLHL-----RHANIRESESTVRILADLQ 277
C + + L + Y++ P + +T+H + AN+ E + L+
Sbjct: 28 CVGCATEERLFHKLFSHYNQFIRPVENVSDPVTVHFEVAITQLANVDEVNQIMETNLWLR 87
Query: 278 MNWIDKRLSWNAGEW-GCSTWLVSSERLWRPNVVLLNAAATTAGDYAL----RARVSNNG 442
W D +L W+ E+ G T V ++++W+P++VL N A GD+ + +A + NG
Sbjct: 88 HIWNDYKLRWDPMEYDGIETLRVPADKIWKPDIVLYNNAV---GDFQVEGKTKALLKYNG 144
Query: 443 SVSWIKRLDISTPISMQLDNWPNDMQTCT 529
++W + M + +P D Q C+
Sbjct: 145 MITWTPPAIFKSSCPMDITFFPFDHQNCS 173
>M83712-1|AAA58357.1| 468|Homo sapiens nicotinic receptor alpha 5
subunit protein.
Length = 468
Score = 49.6 bits (113), Expect = 1e-05
Identities = 31/136 (22%), Positives = 61/136 (44%), Gaps = 6/136 (4%)
Frame = +2
Query: 140 MIDSLLATYDRESPP----DSKIVVNLTLHLRH-ANIRESESTVRILADLQMNWIDKRLS 304
++ L Y+R P + KI + L + ++ E + L+ WID +L
Sbjct: 50 LLKDLFQDYERWVRPVEHLNDKIKIKFGLAISQLVDVDEKNQLMTTNVWLKQEWIDVKLR 109
Query: 305 WNAGEWG-CSTWLVSSERLWRPNVVLLNAAATTAGDYALRARVSNNGSVSWIKRLDISTP 481
WN ++G V S+ W P++VL + A + + + NG+V+W + +
Sbjct: 110 WNPDDYGGIKVIRVPSDSSWTPDIVLFDNADGRFEGTSTKTVIRYNGTVTWTPPANYKSS 169
Query: 482 ISMQLDNWPNDMQTCT 529
++ + +P D+Q C+
Sbjct: 170 CTIDVTFFPFDLQNCS 185
>BC014456-1|AAH14456.1| 494|Homo sapiens cholinergic receptor,
nicotinic, alpha 6 protein.
Length = 494
Score = 49.6 bits (113), Expect = 1e-05
Identities = 35/149 (23%), Positives = 67/149 (44%), Gaps = 10/149 (6%)
Frame = +2
Query: 113 CENATSLSLMIDSLLATYDRESPPDSKIVVNLTLHL-----RHANIRESESTVRILADLQ 277
C + + L + Y++ P + +T+H + AN+ E + L+
Sbjct: 28 CVGCATEERLFHKLFSHYNQFIRPVENVSDPVTVHFEVAITQLANVDEVNQIMETNLWLR 87
Query: 278 MNWIDKRLSWNAGEW-GCSTWLVSSERLWRPNVVLLNAAATTAGDYAL----RARVSNNG 442
W D +L W+ E+ G T V ++++W+P++VL N A GD+ + +A + NG
Sbjct: 88 HIWNDYKLRWDPMEYDGIETLRVPADKIWKPDIVLYNNAV---GDFQVEGKTKALLKYNG 144
Query: 443 SVSWIKRLDISTPISMQLDNWPNDMQTCT 529
++W + M + +P D Q C+
Sbjct: 145 MITWTPPAIFKSSCPMDITFFPFDHQNCS 173
>AC092165-3|AAY24103.1| 520|Homo sapiens unknown protein.
Length = 520
Score = 49.6 bits (113), Expect = 1e-05
Identities = 38/138 (27%), Positives = 63/138 (45%), Gaps = 8/138 (5%)
Frame = +2
Query: 140 MIDSLLATYDRESPPDSKI--VVNLTLHLRHANI---RESESTVRILADLQMNWIDKRLS 304
++ L+ YD P + VVN++L L N+ E E + ++M W D RL
Sbjct: 32 LLADLMQNYDPNLRPAERDSDVVNVSLKLTLTNLISLNEREEALTTNVWIEMQWCDYRLR 91
Query: 305 WNAGEW-GCSTWLVSSERLWRPNVVLLNAAATTAGDYAL--RARVSNNGSVSWIKRLDIS 475
W+ ++ G V S +WRP++VL N + AL VS +G + W+
Sbjct: 92 WDPRDYEGLWVLRVPSTMVWRPDIVLEN-NVDGVFEVALYCNVLVSPDGCIYWLPPAIFR 150
Query: 476 TPISMQLDNWPNDMQTCT 529
+ S+ + +P D Q C+
Sbjct: 151 SACSISVTYFPFDWQNCS 168
>AB079251-1|BAC06855.1| 494|Homo sapiens Nicotinic acetylcholine
receptor alpha 6 protein.
Length = 494
Score = 49.6 bits (113), Expect = 1e-05
Identities = 35/149 (23%), Positives = 67/149 (44%), Gaps = 10/149 (6%)
Frame = +2
Query: 113 CENATSLSLMIDSLLATYDRESPPDSKIVVNLTLHL-----RHANIRESESTVRILADLQ 277
C + + L + Y++ P + +T+H + AN+ E + L+
Sbjct: 28 CVGCATEERLFHKLFSHYNQFIRPVENVSDPVTVHFEVAITQLANVDEVNQIMETNLWLR 87
Query: 278 MNWIDKRLSWNAGEW-GCSTWLVSSERLWRPNVVLLNAAATTAGDYAL----RARVSNNG 442
W D +L W+ E+ G T V ++++W+P++VL N A GD+ + +A + NG
Sbjct: 88 HIWNDYKLRWDPMEYDGIETLRVPADKIWKPDIVLYNNAV---GDFQVEGKTKALLKYNG 144
Query: 443 SVSWIKRLDISTPISMQLDNWPNDMQTCT 529
++W + M + +P D Q C+
Sbjct: 145 MITWTPPAIFKSSCPMDITFFPFDHQNCS 173
>BC111802-1|AAI11803.1| 465|Homo sapiens CHRNG protein protein.
Length = 465
Score = 49.2 bits (112), Expect = 2e-05
Identities = 39/133 (29%), Positives = 62/133 (46%), Gaps = 7/133 (5%)
Frame = +2
Query: 80 LLTCAIASAAECENATSLSLMIDSLLATYDRESPPDSKI--VVNLTLHLRHANI---RES 244
LL A+ A+ N L+ D L+ YD P + VVN++L L N+ E
Sbjct: 11 LLLLAVCLGAQGRNQEE-RLLAD-LMQNYDPNLRPAERDSDVVNVSLKLTLTNLISLNER 68
Query: 245 ESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPNVVLLNAAAT-TAGDYAL 418
E + ++M W D RL W+ ++ G V S +WRP++VL N + T + + L
Sbjct: 69 EEALTTNVWIEMQWCDYRLRWDPRDYEGLWVLRVPSTMVWRPDIVLENKSQTYSTNEIDL 128
Query: 419 RARVSNNGSVSWI 457
+ + S+ WI
Sbjct: 129 QLSQEDGQSIEWI 141
>BC110597-1|AAI10598.1| 411|Homo sapiens ligand-gated ion channel,
zinc activated 1 protein.
Length = 411
Score = 49.2 bits (112), Expect = 2e-05
Identities = 25/86 (29%), Positives = 41/86 (47%)
Frame = +2
Query: 272 LQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPNVVLLNAAATTAGDYALRARVSNNGSVS 451
L+++W+D RL+WN + E LW P + +L A D + +ARV +G V
Sbjct: 86 LRLSWLDTRLAWNTSAHPRHAITLPWESLWTPRLTILEALWVDWRDQSPQARVDQDGHVK 145
Query: 452 WIKRLDISTPISMQLDNWPNDMQTCT 529
L T + +L ++P D C+
Sbjct: 146 LNLALTTETNCNFELLHFPRDHSNCS 171
>AK122638-1|BAC85499.1| 266|Homo sapiens yte protein of 76kDa)
(LCP2). protein.
Length = 266
Score = 49.2 bits (112), Expect = 2e-05
Identities = 25/86 (29%), Positives = 41/86 (47%)
Frame = +2
Query: 272 LQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPNVVLLNAAATTAGDYALRARVSNNGSVS 451
L+++W+D RL+WN + E LW P + +L A D + +ARV +G V
Sbjct: 87 LRLSWLDTRLAWNTSAHPRHAITLPWESLWTPRLTILEALWVDWRDQSPQARVDQDGHVK 146
Query: 452 WIKRLDISTPISMQLDNWPNDMQTCT 529
L T + +L ++P D C+
Sbjct: 147 LNLALTTETNCNFELLHFPRDHSNCS 172
>AF512521-1|AAO20969.1| 411|Homo sapiens ligand-gated ion channel
subunit protein.
Length = 411
Score = 49.2 bits (112), Expect = 2e-05
Identities = 25/86 (29%), Positives = 41/86 (47%)
Frame = +2
Query: 272 LQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPNVVLLNAAATTAGDYALRARVSNNGSVS 451
L+++W+D RL+WN + E LW P + +L A D + +ARV +G V
Sbjct: 86 LRLSWLDTRLAWNTSAHPRHAITLPWESLWTPRLTILEALWVDWRDQSPQARVDQDGHVK 145
Query: 452 WIKRLDISTPISMQLDNWPNDMQTCT 529
L T + +L ++P D C+
Sbjct: 146 LNLALTTETNCNFELLHFPRDHSNCS 171
>Y08421-1|CAA69698.1| 627|Homo sapiens nicotinic acetylcholine
receptor alpha4 subunit precursor protein.
Length = 627
Score = 48.8 bits (111), Expect = 3e-05
Identities = 36/140 (25%), Positives = 70/140 (50%), Gaps = 10/140 (7%)
Frame = +2
Query: 140 MIDSLLATYDRESPPDSKI--VVNLTLHLRHANIRESESTVRILAD---LQMNWIDKRLS 304
++ L + Y++ S P + I VV + L A + + + +++ ++ W D +L
Sbjct: 40 LLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLR 99
Query: 305 WNAGEWGCSTWL-VSSERLWRPNVVLLNAAATTAGDYAL----RARVSNNGSVSWIKRLD 469
W+ ++ T + + SE +WRP++VL N A GD+A+ +A + ++G V W
Sbjct: 100 WDPADYENVTSIRIPSELIWRPDIVLYNNAD---GDFAVTHLTKAHLFHDGRVQWTPPAI 156
Query: 470 ISTPISMQLDNWPNDMQTCT 529
+ S+ + +P D Q CT
Sbjct: 157 YKSSCSIDVTFFPFDQQNCT 176
>X89741-1|CAA61893.1| 627|Homo sapiens neuronal acetylcholine
receptor alpha-4 subunit protein.
Length = 627
Score = 48.8 bits (111), Expect = 3e-05
Identities = 36/140 (25%), Positives = 70/140 (50%), Gaps = 10/140 (7%)
Frame = +2
Query: 140 MIDSLLATYDRESPPDSKI--VVNLTLHLRHANIRESESTVRILAD---LQMNWIDKRLS 304
++ L + Y++ S P + I VV + L A + + + +++ ++ W D +L
Sbjct: 40 LLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLR 99
Query: 305 WNAGEWGCSTWL-VSSERLWRPNVVLLNAAATTAGDYAL----RARVSNNGSVSWIKRLD 469
W+ ++ T + + SE +WRP++VL N A GD+A+ +A + ++G V W
Sbjct: 100 WDPADYENVTSIRIPSELIWRPDIVLYNNAD---GDFAVTHLTKAHLFHDGRVQWTPPAI 156
Query: 470 ISTPISMQLDNWPNDMQTCT 529
+ S+ + +P D Q CT
Sbjct: 157 YKSSCSIDVTFFPFDQQNCT 176
>X87629-1|CAA60959.1| 602|Homo sapiens nicotinic acetylcholine
receptor protein.
Length = 602
Score = 48.8 bits (111), Expect = 3e-05
Identities = 36/140 (25%), Positives = 70/140 (50%), Gaps = 10/140 (7%)
Frame = +2
Query: 140 MIDSLLATYDRESPPDSKI--VVNLTLHLRHANIRESESTVRILAD---LQMNWIDKRLS 304
++ L + Y++ S P + I VV + L A + + + +++ ++ W D +L
Sbjct: 15 LLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLR 74
Query: 305 WNAGEWGCSTWL-VSSERLWRPNVVLLNAAATTAGDYAL----RARVSNNGSVSWIKRLD 469
W+ ++ T + + SE +WRP++VL N A GD+A+ +A + ++G V W
Sbjct: 75 WDPADYENVTSIRIPSELIWRPDIVLYNNAD---GDFAVTHLTKAHLFHDGRVQWTPPAI 131
Query: 470 ISTPISMQLDNWPNDMQTCT 529
+ S+ + +P D Q CT
Sbjct: 132 YKSSCSIDVTFFPFDQQNCT 151
>U62433-1|AAB40111.1| 627|Homo sapiens nicotinic acetylcholine
receptor alpha4 subunit precursor protein.
Length = 627
Score = 48.8 bits (111), Expect = 3e-05
Identities = 36/140 (25%), Positives = 70/140 (50%), Gaps = 10/140 (7%)
Frame = +2
Query: 140 MIDSLLATYDRESPPDSKI--VVNLTLHLRHANIRESESTVRILAD---LQMNWIDKRLS 304
++ L + Y++ S P + I VV + L A + + + +++ ++ W D +L
Sbjct: 40 LLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLR 99
Query: 305 WNAGEWGCSTWL-VSSERLWRPNVVLLNAAATTAGDYAL----RARVSNNGSVSWIKRLD 469
W+ ++ T + + SE +WRP++VL N A GD+A+ +A + ++G V W
Sbjct: 100 WDPADYENVTSIRIPSELIWRPDIVLYNNAD---GDFAVTHLTKAHLFHDGRVQWTPPAI 156
Query: 470 ISTPISMQLDNWPNDMQTCT 529
+ S+ + +P D Q CT
Sbjct: 157 YKSSCSIDVTFFPFDQQNCT 176
>L35901-1|AAA64743.1| 627|Homo sapiens nicotinic acetylcholine
receptor alpha 4 subunit protein.
Length = 627
Score = 48.8 bits (111), Expect = 3e-05
Identities = 36/140 (25%), Positives = 70/140 (50%), Gaps = 10/140 (7%)
Frame = +2
Query: 140 MIDSLLATYDRESPPDSKI--VVNLTLHLRHANIRESESTVRILAD---LQMNWIDKRLS 304
++ L + Y++ S P + I VV + L A + + + +++ ++ W D +L
Sbjct: 40 LLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLR 99
Query: 305 WNAGEWGCSTWL-VSSERLWRPNVVLLNAAATTAGDYAL----RARVSNNGSVSWIKRLD 469
W+ ++ T + + SE +WRP++VL N A GD+A+ +A + ++G V W
Sbjct: 100 WDPADYENVTSIRIPSELIWRPDIVLYNNAD---GDFAVTHLTKAHLFHDGRVQWTPPAI 156
Query: 470 ISTPISMQLDNWPNDMQTCT 529
+ S+ + +P D Q CT
Sbjct: 157 YKSSCSIDVTFFPFDQQNCT 176
>DQ093071-1|AAY88737.1| 627|Homo sapiens cholinergic receptor,
nicotinic, alpha polypeptide 4 protein.
Length = 627
Score = 48.8 bits (111), Expect = 3e-05
Identities = 36/140 (25%), Positives = 70/140 (50%), Gaps = 10/140 (7%)
Frame = +2
Query: 140 MIDSLLATYDRESPPDSKI--VVNLTLHLRHANIRESESTVRILAD---LQMNWIDKRLS 304
++ L + Y++ S P + I VV + L A + + + +++ ++ W D +L
Sbjct: 40 LLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLR 99
Query: 305 WNAGEWGCSTWL-VSSERLWRPNVVLLNAAATTAGDYAL----RARVSNNGSVSWIKRLD 469
W+ ++ T + + SE +WRP++VL N A GD+A+ +A + ++G V W
Sbjct: 100 WDPADYENVTSIRIPSELIWRPDIVLYNNAD---GDFAVTHLTKAHLFHDGRVQWTPPAI 156
Query: 470 ISTPISMQLDNWPNDMQTCT 529
+ S+ + +P D Q CT
Sbjct: 157 YKSSCSIDVTFFPFDQQNCT 176
>BC096290-1|AAH96290.1| 627|Homo sapiens cholinergic receptor,
nicotinic, alpha 4 protein.
Length = 627
Score = 48.8 bits (111), Expect = 3e-05
Identities = 36/140 (25%), Positives = 70/140 (50%), Gaps = 10/140 (7%)
Frame = +2
Query: 140 MIDSLLATYDRESPPDSKI--VVNLTLHLRHANIRESESTVRILAD---LQMNWIDKRLS 304
++ L + Y++ S P + I VV + L A + + + +++ ++ W D +L
Sbjct: 40 LLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLR 99
Query: 305 WNAGEWGCSTWL-VSSERLWRPNVVLLNAAATTAGDYAL----RARVSNNGSVSWIKRLD 469
W+ ++ T + + SE +WRP++VL N A GD+A+ +A + ++G V W
Sbjct: 100 WDPADYENVTSIRIPSELIWRPDIVLYNNAD---GDFAVTHLTKAHLFHDGRVQWTPPAI 156
Query: 470 ISTPISMQLDNWPNDMQTCT 529
+ S+ + +P D Q CT
Sbjct: 157 YKSSCSIDVTFFPFDQQNCT 176
>AB223030-1|BAE19924.1| 411|Homo sapiens ligand-gated ion-channel
receptor L2 protein.
Length = 411
Score = 48.8 bits (111), Expect = 3e-05
Identities = 25/86 (29%), Positives = 41/86 (47%)
Frame = +2
Query: 272 LQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPNVVLLNAAATTAGDYALRARVSNNGSVS 451
L+++W+D RL+WN + E LW P + +L A D + +ARV +G V
Sbjct: 86 LRLSWLDTRLAWNTSAHPRHAITLPWESLWTPRLTILEALWVDWRDQSPQARVDQDGHVK 145
Query: 452 WIKRLDISTPISMQLDNWPNDMQTCT 529
L T + +L ++P D C+
Sbjct: 146 LNLALATETNCNFELLHFPRDHSNCS 171
>Y08415-1|CAA69692.1| 502|Homo sapiens nicotinic acetylcholine
receptor beta2 subunit precursor protein.
Length = 502
Score = 48.4 bits (110), Expect = 3e-05
Identities = 32/119 (26%), Positives = 53/119 (44%), Gaps = 3/119 (2%)
Frame = +2
Query: 194 IVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 367
+ V L + L ++ E E + L W D RL+W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 368 NVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFXVR 541
+VVL N A + A VS +GS+ W+ + +++ ++P D Q CT R
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFR 174
>X53179-1|CAA37320.1| 502|Homo sapiens precursor peptide (AA -25 to
477) protein.
Length = 502
Score = 48.4 bits (110), Expect = 3e-05
Identities = 32/119 (26%), Positives = 53/119 (44%), Gaps = 3/119 (2%)
Frame = +2
Query: 194 IVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 367
+ V L + L ++ E E + L W D RL+W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 368 NVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFXVR 541
+VVL N A + A VS +GS+ W+ + +++ ++P D Q CT R
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFR 174
>U62437-1|AAB40115.1| 502|Homo sapiens nicotinic acetylcholine
receptor beta2 subunit precursor protein.
Length = 502
Score = 48.4 bits (110), Expect = 3e-05
Identities = 32/119 (26%), Positives = 53/119 (44%), Gaps = 3/119 (2%)
Frame = +2
Query: 194 IVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 367
+ V L + L ++ E E + L W D RL+W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 368 NVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFXVR 541
+VVL N A + A VS +GS+ W+ + +++ ++P D Q CT R
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFR 174
>BC075041-1|AAH75041.1| 502|Homo sapiens cholinergic receptor,
nicotinic, beta 2 (neuronal) protein.
Length = 502
Score = 48.4 bits (110), Expect = 3e-05
Identities = 32/119 (26%), Positives = 53/119 (44%), Gaps = 3/119 (2%)
Frame = +2
Query: 194 IVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 367
+ V L + L ++ E E + L W D RL+W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 368 NVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFXVR 541
+VVL N A + A VS +GS+ W+ + +++ ++P D Q CT R
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFR 174
>BC075040-1|AAH75040.1| 502|Homo sapiens cholinergic receptor,
nicotinic, beta 2 (neuronal) protein.
Length = 502
Score = 48.4 bits (110), Expect = 3e-05
Identities = 32/119 (26%), Positives = 53/119 (44%), Gaps = 3/119 (2%)
Frame = +2
Query: 194 IVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 367
+ V L + L ++ E E + L W D RL+W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 368 NVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFXVR 541
+VVL N A + A VS +GS+ W+ + +++ ++P D Q CT R
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFR 174
>AL592078-3|CAI16184.1| 502|Homo sapiens cholinergic receptor,
nicotinic, beta 2 (neuronal) protein.
Length = 502
Score = 48.4 bits (110), Expect = 3e-05
Identities = 32/119 (26%), Positives = 53/119 (44%), Gaps = 3/119 (2%)
Frame = +2
Query: 194 IVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 367
+ V L + L ++ E E + L W D RL+W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 368 NVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFXVR 541
+VVL N A + A VS +GS+ W+ + +++ ++P D Q CT R
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFR 174
>AF077186-1|AAD45422.1| 502|Homo sapiens neuronal nicotinic
acetylcholine receptor beta 2 protein.
Length = 502
Score = 48.4 bits (110), Expect = 3e-05
Identities = 32/119 (26%), Positives = 53/119 (44%), Gaps = 3/119 (2%)
Frame = +2
Query: 194 IVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 367
+ V L + L ++ E E + L W D RL+W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 368 NVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFXVR 541
+VVL N A + A VS +GS+ W+ + +++ ++P D Q CT R
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFR 174
>X55019-1|CAA38759.1| 517|Homo sapiens acetylcholine receptor delta
subunit protein.
Length = 517
Score = 47.6 bits (108), Expect = 6e-05
Identities = 34/129 (26%), Positives = 59/129 (45%), Gaps = 7/129 (5%)
Frame = +2
Query: 164 YDRESPP----DSKIVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEWG- 325
Y++E P + + V L L L + +++E E T+ ++ W D RL WNA E+G
Sbjct: 38 YNKELRPVAHKEESVDVALALTLSNLISLKEVEETLTTNVWIEHGWTDNRLKWNAEEFGN 97
Query: 326 CSTWLVSSERLWRPNVVL-LNAAATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDN 502
S + + +W P +VL N + Y+ V + G V W+ + + +
Sbjct: 98 ISVLRLPPDMVWLPEIVLENNNDGSFQISYSCNVLVYHYGFVYWLPPAIFRSSCPISVTY 157
Query: 503 WPNDMQTCT 529
+P D Q C+
Sbjct: 158 FPFDWQNCS 166
>BC093925-1|AAH93925.1| 517|Homo sapiens cholinergic receptor,
nicotinic, delta protein.
Length = 517
Score = 47.6 bits (108), Expect = 6e-05
Identities = 34/129 (26%), Positives = 59/129 (45%), Gaps = 7/129 (5%)
Frame = +2
Query: 164 YDRESPP----DSKIVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEWG- 325
Y++E P + + V L L L + +++E E T+ ++ W D RL WNA E+G
Sbjct: 38 YNKELRPVAHKEESVDVALALTLSNLISLKEVEETLTTNVWIEHGWTDNRLKWNAEEFGN 97
Query: 326 CSTWLVSSERLWRPNVVL-LNAAATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDN 502
S + + +W P +VL N + Y+ V + G V W+ + + +
Sbjct: 98 ISVLRLPPDMVWLPEIVLENNNDGSFQISYSCNVLVYHYGFVYWLPPAIFRSSCPISVTY 157
Query: 503 WPNDMQTCT 529
+P D Q C+
Sbjct: 158 FPFDWQNCS 166
>BC093923-1|AAH93923.1| 517|Homo sapiens cholinergic receptor,
nicotinic, delta protein.
Length = 517
Score = 47.6 bits (108), Expect = 6e-05
Identities = 34/129 (26%), Positives = 59/129 (45%), Gaps = 7/129 (5%)
Frame = +2
Query: 164 YDRESPP----DSKIVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEWG- 325
Y++E P + + V L L L + +++E E T+ ++ W D RL WNA E+G
Sbjct: 38 YNKELRPVAHKEESVDVALALTLSNLISLKEVEETLTTNVWIEHGWTDNRLKWNAEEFGN 97
Query: 326 CSTWLVSSERLWRPNVVL-LNAAATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDN 502
S + + +W P +VL N + Y+ V + G V W+ + + +
Sbjct: 98 ISVLRLPPDMVWLPEIVLENNNDGSFQISYSCNVLVYHYGFVYWLPPAIFRSSCPISVTY 157
Query: 503 WPNDMQTCT 529
+P D Q C+
Sbjct: 158 FPFDWQNCS 166
>AC092165-2|AAY24102.1| 517|Homo sapiens unknown protein.
Length = 517
Score = 47.6 bits (108), Expect = 6e-05
Identities = 34/129 (26%), Positives = 59/129 (45%), Gaps = 7/129 (5%)
Frame = +2
Query: 164 YDRESPP----DSKIVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEWG- 325
Y++E P + + V L L L + +++E E T+ ++ W D RL WNA E+G
Sbjct: 38 YNKELRPVAHKEESVDVALALTLSNLISLKEVEETLTTNVWIEHGWTDNRLKWNAEEFGN 97
Query: 326 CSTWLVSSERLWRPNVVL-LNAAATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDN 502
S + + +W P +VL N + Y+ V + G V W+ + + +
Sbjct: 98 ISVLRLPPDMVWLPEIVLENNNDGSFQISYSCNVLVYHYGFVYWLPPAIFRSSCPISVTY 157
Query: 503 WPNDMQTCT 529
+P D Q C+
Sbjct: 158 FPFDWQNCS 166
>M59216-1|AAA35862.1| 474|Homo sapiens gamma-aminobutyric acid
receptor beta-1 subunit protein.
Length = 474
Score = 46.8 bits (106), Expect = 1e-04
Identities = 38/168 (22%), Positives = 69/168 (41%), Gaps = 7/168 (4%)
Frame = +2
Query: 56 LILFCYRFLLTCAIASAAECENATSLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRH 226
L+ F + C S E N + + +D LL YD PD + V + + +
Sbjct: 12 LLSFPVMITMVCCAHSTNEPSNMSYVKETVDRLLKGYDIRLRPDFGGPPVDVGMRIDVAS 71
Query: 227 AN-IRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPNVVLLNAAATTA 403
+ + E + Q +W DKRLS++ + +++LW P+ LN +
Sbjct: 72 IDMVSEVNMDYTLTMYFQQSWKDKRLSYSGIPLNLTLDNRVADQLWVPDTYFLNDKKSFV 131
Query: 404 GDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFXV 538
++ R+ +G+V + R+ + M L +P D Q CT +
Sbjct: 132 HGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEI 179
>DQ644022-1|ABG35128.1| 456|Homo sapiens 5-HT3 receptor subunit E
splice variant HTR3Ea protein.
Length = 456
Score = 46.8 bits (106), Expect = 1e-04
Identities = 23/87 (26%), Positives = 44/87 (50%), Gaps = 1/87 (1%)
Frame = +2
Query: 272 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPNVVLLNAAATTAGDYALRARVSNNGSV 448
L+M W + +SWN E G + ++++ LW P++ ++ L A VSN G +
Sbjct: 91 LEMVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEGRI 150
Query: 449 SWIKRLDISTPISMQLDNWPNDMQTCT 529
+ K + + + ++ + +P D Q CT
Sbjct: 151 RYKKPMKVDSICNLDIFYFPFDQQNCT 177
>BC101185-1|AAI01186.1| 374|Homo sapiens HTR3E protein protein.
Length = 374
Score = 46.8 bits (106), Expect = 1e-04
Identities = 23/87 (26%), Positives = 44/87 (50%), Gaps = 1/87 (1%)
Frame = +2
Query: 272 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPNVVLLNAAATTAGDYALRARVSNNGSV 448
L+M W + +SWN E G + ++++ LW P++ ++ L A VSN G +
Sbjct: 20 LEMVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEGRI 79
Query: 449 SWIKRLDISTPISMQLDNWPNDMQTCT 529
+ K + + + ++ + +P D Q CT
Sbjct: 80 RYKKPMKVDSICNLDIFYFPFDQQNCT 106
>BC101183-1|AAI01184.1| 471|Homo sapiens 5-hydroxytryptamine
(serotonin) receptor 3, family member E protein.
Length = 471
Score = 46.8 bits (106), Expect = 1e-04
Identities = 23/87 (26%), Positives = 44/87 (50%), Gaps = 1/87 (1%)
Frame = +2
Query: 272 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPNVVLLNAAATTAGDYALRARVSNNGSV 448
L+M W + +SWN E G + ++++ LW P++ ++ L A VSN G +
Sbjct: 106 LEMVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEGRI 165
Query: 449 SWIKRLDISTPISMQLDNWPNDMQTCT 529
+ K + + + ++ + +P D Q CT
Sbjct: 166 RYKKPMKVDSICNLDIFYFPFDQQNCT 192
>BC101182-1|AAI01183.1| 471|Homo sapiens 5-hydroxytryptamine
(serotonin) receptor 3, family member E protein.
Length = 471
Score = 46.8 bits (106), Expect = 1e-04
Identities = 23/87 (26%), Positives = 44/87 (50%), Gaps = 1/87 (1%)
Frame = +2
Query: 272 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPNVVLLNAAATTAGDYALRARVSNNGSV 448
L+M W + +SWN E G + ++++ LW P++ ++ L A VSN G +
Sbjct: 106 LEMVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEGRI 165
Query: 449 SWIKRLDISTPISMQLDNWPNDMQTCT 529
+ K + + + ++ + +P D Q CT
Sbjct: 166 RYKKPMKVDSICNLDIFYFPFDQQNCT 192
>AY159813-1|AAO38167.2| 471|Homo sapiens 5-hydroxytryptamine
serotonin receptor 3E protein.
Length = 471
Score = 46.8 bits (106), Expect = 1e-04
Identities = 23/87 (26%), Positives = 44/87 (50%), Gaps = 1/87 (1%)
Frame = +2
Query: 272 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPNVVLLNAAATTAGDYALRARVSNNGSV 448
L+M W + +SWN E G + ++++ LW P++ ++ L A VSN G +
Sbjct: 106 LEMVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEGRI 165
Query: 449 SWIKRLDISTPISMQLDNWPNDMQTCT 529
+ K + + + ++ + +P D Q CT
Sbjct: 166 RYKKPMKVDSICNLDIFYFPFDQQNCT 192
>X14767-1|CAA32875.1| 474|Homo sapiens GABA-A receptor beta 1
subunit protein.
Length = 474
Score = 46.0 bits (104), Expect = 2e-04
Identities = 38/168 (22%), Positives = 68/168 (40%), Gaps = 7/168 (4%)
Frame = +2
Query: 56 LILFCYRFLLTCAIASAAECENATSLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRH 226
L+ F + C S E N + +D LL YD PD + V + + +
Sbjct: 12 LLSFPVMITMVCCAHSTNEPSNMPYVKETVDRLLKGYDIRLRPDFGGPPVDVGMRIDVAS 71
Query: 227 AN-IRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPNVVLLNAAATTA 403
+ + E + Q +W DKRLS++ + +++LW P+ LN +
Sbjct: 72 IDMVSEVNMDYTLTMYFQQSWKDKRLSYSGIPLNLTLDNRVADQLWVPDTYFLNDKKSFV 131
Query: 404 GDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFXV 538
++ R+ +G+V + R+ + M L +P D Q CT +
Sbjct: 132 HGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEI 179
>S77554-1|AAB33983.1| 474|Homo sapiens GABAA receptor beta 2
subunit protein.
Length = 474
Score = 46.0 bits (104), Expect = 2e-04
Identities = 39/166 (23%), Positives = 70/166 (42%), Gaps = 10/166 (6%)
Frame = +2
Query: 71 YRFLLTCAIASAAECENATSLSLM---IDSLLATYDRESPPD---SKIVVNLTLHLRHAN 232
+ F L A A + +++SL+ +D LL YD PD + V + + + +
Sbjct: 13 WSFPLIIAAVCAQSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDIASID 72
Query: 233 -IRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPNVVLLNAAATTAGD 409
+ E + Q W DKRLS+N + +++LW P+ LN +
Sbjct: 73 MVSEVNMDYTLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHG 132
Query: 410 YALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFXV 538
++ R+ +G+V + R+ + M L +P D Q CT +
Sbjct: 133 VTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEI 178
>S77553-1|AAB33982.1| 512|Homo sapiens GABAA receptor beta 2
subunit protein.
Length = 512
Score = 46.0 bits (104), Expect = 2e-04
Identities = 39/166 (23%), Positives = 70/166 (42%), Gaps = 10/166 (6%)
Frame = +2
Query: 71 YRFLLTCAIASAAECENATSLSLM---IDSLLATYDRESPPD---SKIVVNLTLHLRHAN 232
+ F L A A + +++SL+ +D LL YD PD + V + + + +
Sbjct: 13 WSFPLIIAAVCAQSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDIASID 72
Query: 233 -IRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPNVVLLNAAATTAGD 409
+ E + Q W DKRLS+N + +++LW P+ LN +
Sbjct: 73 MVSEVNMDYTLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHG 132
Query: 410 YALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFXV 538
++ R+ +G+V + R+ + M L +P D Q CT +
Sbjct: 133 VTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEI 178
>S67368-1|AAB29370.1| 474|Homo sapiens gamma-aminobutyric acid A
receptor beta 2 subunit protein.
Length = 474
Score = 46.0 bits (104), Expect = 2e-04
Identities = 39/166 (23%), Positives = 70/166 (42%), Gaps = 10/166 (6%)
Frame = +2
Query: 71 YRFLLTCAIASAAECENATSLSLM---IDSLLATYDRESPPD---SKIVVNLTLHLRHAN 232
+ F L A A + +++SL+ +D LL YD PD + V + + + +
Sbjct: 13 WSFPLIIAAVCAQSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDIASID 72
Query: 233 -IRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPNVVLLNAAATTAGD 409
+ E + Q W DKRLS+N + +++LW P+ LN +
Sbjct: 73 MVSEVNMDYTLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHG 132
Query: 410 YALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFXV 538
++ R+ +G+V + R+ + M L +P D Q CT +
Sbjct: 133 VTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEI 178
>BC105639-1|AAI05640.1| 474|Homo sapiens GABRB2 protein protein.
Length = 474
Score = 46.0 bits (104), Expect = 2e-04
Identities = 39/166 (23%), Positives = 70/166 (42%), Gaps = 10/166 (6%)
Frame = +2
Query: 71 YRFLLTCAIASAAECENATSLSLM---IDSLLATYDRESPPD---SKIVVNLTLHLRHAN 232
+ F L A A + +++SL+ +D LL YD PD + V + + + +
Sbjct: 13 WSFPLIIAAVCAQSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDIASID 72
Query: 233 -IRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPNVVLLNAAATTAGD 409
+ E + Q W DKRLS+N + +++LW P+ LN +
Sbjct: 73 MVSEVNMDYTLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHG 132
Query: 410 YALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFXV 538
++ R+ +G+V + R+ + M L +P D Q CT +
Sbjct: 133 VTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEI 178
>BC099719-1|AAH99719.1| 474|Homo sapiens GABRB2 protein protein.
Length = 474
Score = 46.0 bits (104), Expect = 2e-04
Identities = 39/166 (23%), Positives = 70/166 (42%), Gaps = 10/166 (6%)
Frame = +2
Query: 71 YRFLLTCAIASAAECENATSLSLM---IDSLLATYDRESPPD---SKIVVNLTLHLRHAN 232
+ F L A A + +++SL+ +D LL YD PD + V + + + +
Sbjct: 13 WSFPLIIAAVCAQSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDIASID 72
Query: 233 -IRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPNVVLLNAAATTAGD 409
+ E + Q W DKRLS+N + +++LW P+ LN +
Sbjct: 73 MVSEVNMDYTLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHG 132
Query: 410 YALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFXV 538
++ R+ +G+V + R+ + M L +P D Q CT +
Sbjct: 133 VTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEI 178
>BC099705-1|AAH99705.1| 474|Homo sapiens GABRB2 protein protein.
Length = 474
Score = 46.0 bits (104), Expect = 2e-04
Identities = 39/166 (23%), Positives = 70/166 (42%), Gaps = 10/166 (6%)
Frame = +2
Query: 71 YRFLLTCAIASAAECENATSLSLM---IDSLLATYDRESPPD---SKIVVNLTLHLRHAN 232
+ F L A A + +++SL+ +D LL YD PD + V + + + +
Sbjct: 13 WSFPLIIAAVCAQSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDIASID 72
Query: 233 -IRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPNVVLLNAAATTAGD 409
+ E + Q W DKRLS+N + +++LW P+ LN +
Sbjct: 73 MVSEVNMDYTLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHG 132
Query: 410 YALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFXV 538
++ R+ +G+V + R+ + M L +P D Q CT +
Sbjct: 133 VTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEI 178
>U77731-2|AAB38273.1| 360|Homo sapiens glycine receptor alpha 2B
subunit protein.
Length = 360
Score = 45.6 bits (103), Expect = 2e-04
Identities = 36/130 (27%), Positives = 58/130 (44%), Gaps = 8/130 (6%)
Frame = +2
Query: 164 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 331
YD P+ K VN+T ++ +I E+ R+ L+ W D RL+++
Sbjct: 58 YDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDSRLAYSEYPDDSL 117
Query: 332 TWLVSS-ERLWRPNVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLD 499
S + +W+P++ N D R+S NG V + RL ++ M L
Sbjct: 118 DLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLK 177
Query: 500 NWPNDMQTCT 529
N+P D+QTCT
Sbjct: 178 NFPMDVQTCT 187
>CR450343-1|CAG29339.1| 452|Homo sapiens GLRA2 protein.
Length = 452
Score = 45.6 bits (103), Expect = 2e-04
Identities = 36/130 (27%), Positives = 58/130 (44%), Gaps = 8/130 (6%)
Frame = +2
Query: 164 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 331
YD P+ K VN+T ++ +I E+ R+ L+ W D RL+++
Sbjct: 58 YDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDSRLAYSEYPDDSL 117
Query: 332 TWLVSS-ERLWRPNVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLD 499
S + +W+P++ N D R+S NG V + RL ++ M L
Sbjct: 118 DLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLK 177
Query: 500 NWPNDMQTCT 529
N+P D+QTCT
Sbjct: 178 NFPMDVQTCT 187
>AY437084-1|AAR87843.1| 452|Homo sapiens glycine receptor alpha2
subunit B protein.
Length = 452
Score = 45.6 bits (103), Expect = 2e-04
Identities = 36/130 (27%), Positives = 58/130 (44%), Gaps = 8/130 (6%)
Frame = +2
Query: 164 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 331
YD P+ K VN+T ++ +I E+ R+ L+ W D RL+++
Sbjct: 58 YDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDSRLAYSEYPDDSL 117
Query: 332 TWLVSS-ERLWRPNVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLD 499
S + +W+P++ N D R+S NG V + RL ++ M L
Sbjct: 118 DLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLK 177
Query: 500 NWPNDMQTCT 529
N+P D+QTCT
Sbjct: 178 NFPMDVQTCT 187
>X52008-1|CAA36257.1| 452|Homo sapiens inhibitory glycine receptor
protein.
Length = 452
Score = 45.2 bits (102), Expect = 3e-04
Identities = 35/130 (26%), Positives = 58/130 (44%), Gaps = 8/130 (6%)
Frame = +2
Query: 164 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 331
YD P+ K VN+T ++ ++ E+ R+ L+ W D RL+++
Sbjct: 58 YDARIRPNFKGPPVNVTCNIFINSFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPDDSL 117
Query: 332 TWLVSS-ERLWRPNVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLD 499
S + +W+P++ N D R+S NG V + RL ++ M L
Sbjct: 118 DLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLK 177
Query: 500 NWPNDMQTCT 529
N+P D+QTCT
Sbjct: 178 NFPMDVQTCT 187
>U77731-1|AAB38272.1| 360|Homo sapiens glycine receptor alpha 2
subunit protein.
Length = 360
Score = 45.2 bits (102), Expect = 3e-04
Identities = 35/130 (26%), Positives = 58/130 (44%), Gaps = 8/130 (6%)
Frame = +2
Query: 164 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 331
YD P+ K VN+T ++ ++ E+ R+ L+ W D RL+++
Sbjct: 58 YDARIRPNFKGPPVNVTCNIFINSFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPDDSL 117
Query: 332 TWLVSS-ERLWRPNVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLD 499
S + +W+P++ N D R+S NG V + RL ++ M L
Sbjct: 118 DLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLK 177
Query: 500 NWPNDMQTCT 529
N+P D+QTCT
Sbjct: 178 NFPMDVQTCT 187
>BC032864-1|AAH32864.1| 452|Homo sapiens glycine receptor, alpha 2
protein.
Length = 452
Score = 45.2 bits (102), Expect = 3e-04
Identities = 35/130 (26%), Positives = 58/130 (44%), Gaps = 8/130 (6%)
Frame = +2
Query: 164 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 331
YD P+ K VN+T ++ ++ E+ R+ L+ W D RL+++
Sbjct: 58 YDARIRPNFKGPPVNVTCNIFINSFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPDDSL 117
Query: 332 TWLVSS-ERLWRPNVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLD 499
S + +W+P++ N D R+S NG V + RL ++ M L
Sbjct: 118 DLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLK 177
Query: 500 NWPNDMQTCT 529
N+P D+QTCT
Sbjct: 178 NFPMDVQTCT 187
>AY437083-1|AAR87842.1| 452|Homo sapiens glycine receptor alpha2
subunit A protein.
Length = 452
Score = 45.2 bits (102), Expect = 3e-04
Identities = 35/130 (26%), Positives = 58/130 (44%), Gaps = 8/130 (6%)
Frame = +2
Query: 164 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 331
YD P+ K VN+T ++ ++ E+ R+ L+ W D RL+++
Sbjct: 58 YDARIRPNFKGPPVNVTCNIFINSFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPDDSL 117
Query: 332 TWLVSS-ERLWRPNVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLD 499
S + +W+P++ N D R+S NG V + RL ++ M L
Sbjct: 118 DLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLK 177
Query: 500 NWPNDMQTCT 529
N+P D+QTCT
Sbjct: 178 NFPMDVQTCT 187
>AF053495-1|AAC35290.1| 452|Homo sapiens glycine receptor alpha 2
subunit protein.
Length = 452
Score = 45.2 bits (102), Expect = 3e-04
Identities = 35/130 (26%), Positives = 58/130 (44%), Gaps = 8/130 (6%)
Frame = +2
Query: 164 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 331
YD P+ K VN+T ++ ++ E+ R+ L+ W D RL+++
Sbjct: 58 YDARIRPNFKGPPVNVTCNIFINSFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPDDSL 117
Query: 332 TWLVSS-ERLWRPNVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLD 499
S + +W+P++ N D R+S NG V + RL ++ M L
Sbjct: 118 DLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLK 177
Query: 500 NWPNDMQTCT 529
N+P D+QTCT
Sbjct: 178 NFPMDVQTCT 187
>AY349353-1|AAQ93477.1| 456|Homo sapiens 5-HT3c1 serotonin
receptor-like protein protein.
Length = 456
Score = 44.8 bits (101), Expect = 4e-04
Identities = 23/89 (25%), Positives = 44/89 (49%), Gaps = 1/89 (1%)
Frame = +2
Query: 266 ADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPNVVLLNAAATTAGDYALRARVSNNG 442
A L + W + +SWN E G + ++++ LW P++ ++ L A VSN G
Sbjct: 89 AILDVVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEG 148
Query: 443 SVSWIKRLDISTPISMQLDNWPNDMQTCT 529
+ + K + + + ++ + +P D Q CT
Sbjct: 149 RIRYKKPMKVDSICNLDIFYFPFDQQNCT 177
>AY349352-1|AAQ93476.1| 441|Homo sapiens 5-HT3c1 serotonin
receptor-like protein protein.
Length = 441
Score = 44.8 bits (101), Expect = 4e-04
Identities = 23/89 (25%), Positives = 44/89 (49%), Gaps = 1/89 (1%)
Frame = +2
Query: 266 ADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPNVVLLNAAATTAGDYALRARVSNNG 442
A L + W + +SWN E G + ++++ LW P++ ++ L A VSN G
Sbjct: 74 AILDVVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEG 133
Query: 443 SVSWIKRLDISTPISMQLDNWPNDMQTCT 529
+ + K + + + ++ + +P D Q CT
Sbjct: 134 RIRYKKPMKVDSICNLDIFYFPFDQQNCT 162
>BC096083-1|AAH96083.1| 198|Homo sapiens CHRNB4 protein protein.
Length = 198
Score = 44.4 bits (100), Expect = 5e-04
Identities = 29/115 (25%), Positives = 54/115 (46%), Gaps = 8/115 (6%)
Frame = +2
Query: 92 AIASAAECENATSLSLMIDSLL--ATYDRESPP--DSKIVVNLTLHLRHA---NIRESES 250
A+ C A + ++D LL Y+ P S ++++ L L A ++ E E
Sbjct: 14 ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQ 73
Query: 251 TVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPNVVLLNAAATTAGDY 412
+ L+ W D RL+WN+ + G + + ++R+W P++VL N + T +
Sbjct: 74 IMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNKSLRTGSTW 128
>BC096081-1|AAH96081.1| 198|Homo sapiens CHRNB4 protein protein.
Length = 198
Score = 44.4 bits (100), Expect = 5e-04
Identities = 29/115 (25%), Positives = 54/115 (46%), Gaps = 8/115 (6%)
Frame = +2
Query: 92 AIASAAECENATSLSLMIDSLL--ATYDRESPP--DSKIVVNLTLHLRHA---NIRESES 250
A+ C A + ++D LL Y+ P S ++++ L L A ++ E E
Sbjct: 14 ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQ 73
Query: 251 TVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPNVVLLNAAATTAGDY 412
+ L+ W D RL+WN+ + G + + ++R+W P++VL N + T +
Sbjct: 74 IMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNKSLRTGSTW 128
>BC114947-1|AAI14948.1| 457|Homo sapiens GLRA1 protein protein.
Length = 457
Score = 42.7 bits (96), Expect = 0.002
Identities = 43/174 (24%), Positives = 78/174 (44%), Gaps = 17/174 (9%)
Frame = +2
Query: 56 LILFCYRFLLTCAIASAAECENATSL------SLMIDSLLAT---YDRESPPDSK-IVVN 205
L L+ + ++ ++A++ E E A S S +D L+ YD P+ K VN
Sbjct: 7 LRLYLWETIVFFSLAASKEAEAARSAPKPMSPSDFLDKLMGRTSGYDARIRPNFKGPPVN 66
Query: 206 LTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERLWRPNV 373
++ ++ +I E+ R+ L+ W D RL++N S + +W+P++
Sbjct: 67 VSCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYNEYPDDSLDLDPSMLDSIWKPDL 126
Query: 374 VLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTC 526
N + R+S NG+V + R+ ++ M L N+P D+QTC
Sbjct: 127 FFANEKGAHFHEITTDNKLLRISRNGNVLYSIRITLTLACPMDLKNFPMDVQTC 180
>BC074980-1|AAH74980.1| 449|Homo sapiens glycine receptor, alpha 1
(startle disease/hyperekplexia) protein.
Length = 449
Score = 42.7 bits (96), Expect = 0.002
Identities = 43/174 (24%), Positives = 78/174 (44%), Gaps = 17/174 (9%)
Frame = +2
Query: 56 LILFCYRFLLTCAIASAAECENATSL------SLMIDSLLAT---YDRESPPDSK-IVVN 205
L L+ + ++ ++A++ E E A S S +D L+ YD P+ K VN
Sbjct: 7 LRLYLWETIVFFSLAASKEAEAARSAPKPMSPSDFLDKLMGRTSGYDARIRPNFKGPPVN 66
Query: 206 LTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERLWRPNV 373
++ ++ +I E+ R+ L+ W D RL++N S + +W+P++
Sbjct: 67 VSCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYNEYPDDSLDLDPSMLDSIWKPDL 126
Query: 374 VLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTC 526
N + R+S NG+V + R+ ++ M L N+P D+QTC
Sbjct: 127 FFANEKGAHFHEITTDNKLLRISRNGNVLYSIRITLTLACPMDLKNFPMDVQTC 180
>S82769-1|AAB39369.1| 467|Homo sapiens GABAA receptor gamma 3
subunit protein.
Length = 467
Score = 42.3 bits (95), Expect = 0.002
Identities = 32/141 (22%), Positives = 62/141 (43%), Gaps = 7/141 (4%)
Frame = +2
Query: 125 TSLSLMIDSLLATYDRESPPDSKI---VVNLTLHLRHAN-IRESESTVRILADLQMNWID 292
T ++L+++ LL YD++ PD I V+++ +++ + +I W D
Sbjct: 45 TDVTLILNKLLREYDKKLRPDIGIKPTVIDVDIYVNSIGPVSSINMEYQIDIFFAQTWTD 104
Query: 293 KRLSWNAGEWGCSTWLVSSERLWRPNVVLLNAAATTAGDYALR---ARVSNNGSVSWIKR 463
RL +N+ + +W P+ + N+ A R+ N+G + + R
Sbjct: 105 SRLRFNSTMKILTLNSNMVGLIWIPDTIFRNSKTAEAHWITTPNQLLRIWNDGKILYTLR 164
Query: 464 LDISTPISMQLDNWPNDMQTC 526
L I+ +QL N+P D +C
Sbjct: 165 LTINAECQLQLHNFPMDEHSC 185
>AF269144-1|AAF99698.1| 467|Homo sapiens GABAA receptor gamma 3
subunit protein.
Length = 467
Score = 42.3 bits (95), Expect = 0.002
Identities = 32/141 (22%), Positives = 62/141 (43%), Gaps = 7/141 (4%)
Frame = +2
Query: 125 TSLSLMIDSLLATYDRESPPDSKI---VVNLTLHLRHAN-IRESESTVRILADLQMNWID 292
T ++L+++ LL YD++ PD I V+++ +++ + +I W D
Sbjct: 45 TDVTLILNKLLREYDKKLRPDIGIKPTVIDVDIYVNSIGPVSSINMEYQIDIFFAQTWTD 104
Query: 293 KRLSWNAGEWGCSTWLVSSERLWRPNVVLLNAAATTAGDYALR---ARVSNNGSVSWIKR 463
RL +N+ + +W P+ + N+ A R+ N+G + + R
Sbjct: 105 SRLRFNSTMKILTLNSNMVGLIWIPDTIFRNSKTAEAHWITTPNQLLRIWNDGKILYTLR 164
Query: 464 LDISTPISMQLDNWPNDMQTC 526
L I+ +QL N+P D +C
Sbjct: 165 LTINAECQLQLHNFPMDEHSC 185
>AF228458-1|AAF63215.1| 449|Homo sapiens GABAA receptor gamma 3
subunit protein.
Length = 449
Score = 42.3 bits (95), Expect = 0.002
Identities = 32/141 (22%), Positives = 62/141 (43%), Gaps = 7/141 (4%)
Frame = +2
Query: 125 TSLSLMIDSLLATYDRESPPDSKI---VVNLTLHLRHAN-IRESESTVRILADLQMNWID 292
T ++L+++ LL YD++ PD I V+++ +++ + +I W D
Sbjct: 27 TDVTLILNKLLREYDKKLRPDIGIKPTVIDVDIYVNSIGPVSSINMEYQIDIFFAQTWTD 86
Query: 293 KRLSWNAGEWGCSTWLVSSERLWRPNVVLLNAAATTAGDYALR---ARVSNNGSVSWIKR 463
RL +N+ + +W P+ + N+ A R+ N+G + + R
Sbjct: 87 SRLRFNSTMKILTLNSNMVGLIWIPDTIFRNSKTAEAHWITTPNQLLRIWNDGKILYTLR 146
Query: 464 LDISTPISMQLDNWPNDMQTC 526
L I+ +QL N+P D +C
Sbjct: 147 LTINAECQLQLHNFPMDEHSC 167
>BC033801-1|AAH33801.1| 452|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, delta protein.
Length = 452
Score = 41.9 bits (94), Expect = 0.003
Identities = 35/135 (25%), Positives = 57/135 (42%), Gaps = 7/135 (5%)
Frame = +2
Query: 143 IDSLLATYDRESPPD-SKIVVNLTLHLRHANI---RESESTVRILADLQMNWIDKRLSWN 310
+D L+A Y R P VN+ L L A+I E+ + L +W D RLS+N
Sbjct: 44 LDGLIAGYARNFRPGIGGPPVNVALALEVASIDHISEANMEYTMTVFLHQSWRDSRLSYN 103
Query: 311 AGEWGCSTWLVSSERLWRPNVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTP 481
++LW P+ ++NA + D + R+ +G + + R+ +
Sbjct: 104 HTNETLGLDSRFVDKLWLPDTFIVNAKSAWFHDVTVENKLIRLQPDGVILYSIRITSTVA 163
Query: 482 ISMQLDNWPNDMQTC 526
M L +P D Q C
Sbjct: 164 CDMDLAKYPMDEQEC 178
>AL391845-4|CAI15436.1| 452|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, delta protein.
Length = 452
Score = 41.9 bits (94), Expect = 0.003
Identities = 35/135 (25%), Positives = 57/135 (42%), Gaps = 7/135 (5%)
Frame = +2
Query: 143 IDSLLATYDRESPPD-SKIVVNLTLHLRHANI---RESESTVRILADLQMNWIDKRLSWN 310
+D L+A Y R P VN+ L L A+I E+ + L +W D RLS+N
Sbjct: 44 LDGLIAGYARNFRPGIGGPPVNVALALEVASIDHISEANMEYTMTVFLHQSWRDSRLSYN 103
Query: 311 AGEWGCSTWLVSSERLWRPNVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTP 481
++LW P+ ++NA + D + R+ +G + + R+ +
Sbjct: 104 HTNETLGLDSRFVDKLWLPDTFIVNAKSAWFHDVTVENKLIRLQPDGVILYSIRITSTVA 163
Query: 482 ISMQLDNWPNDMQTC 526
M L +P D Q C
Sbjct: 164 CDMDLAKYPMDEQEC 178
>AF016917-1|AAB70007.1| 452|Homo sapiens GABA-A receptor delta
subunit protein.
Length = 452
Score = 41.9 bits (94), Expect = 0.003
Identities = 35/135 (25%), Positives = 57/135 (42%), Gaps = 7/135 (5%)
Frame = +2
Query: 143 IDSLLATYDRESPPD-SKIVVNLTLHLRHANI---RESESTVRILADLQMNWIDKRLSWN 310
+D L+A Y R P VN+ L L A+I E+ + L +W D RLS+N
Sbjct: 44 LDGLIAGYARNFRPGIGGPPVNVALALEVASIDHISEANMEYTMTVFLHQSWRDSRLSYN 103
Query: 311 AGEWGCSTWLVSSERLWRPNVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTP 481
++LW P+ ++NA + D + R+ +G + + R+ +
Sbjct: 104 HTNETLGLDSRFVDKLWLPDTFIVNAKSAWFHDVTVENKLIRLQPDGVILYSIRITSTVA 163
Query: 482 ISMQLDNWPNDMQTC 526
M L +P D Q C
Sbjct: 164 CDMDLAKYPMDEQEC 178
>BC022449-1|AAH22449.1| 474|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, beta 1 protein.
Length = 474
Score = 41.5 bits (93), Expect = 0.004
Identities = 37/168 (22%), Positives = 68/168 (40%), Gaps = 7/168 (4%)
Frame = +2
Query: 56 LILFCYRFLLTCAIASAAECENATSLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRH 226
L+ F + C S E N + + +D LL YD PD + V + + +
Sbjct: 12 LLSFPVMITMVCCAHSTNEPSNMSYVKETVDRLLKGYDIRLRPDFGGPPVDVGMRIDVAS 71
Query: 227 AN-IRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPNVVLLNAAATTA 403
+ + E + Q +W DKRLS++ + +++L P+ LN +
Sbjct: 72 IDMVSEVNMDYTLTMYFQQSWKDKRLSYSGIPLNLTLDNRVADQLCVPDTYFLNDKKSFV 131
Query: 404 GDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFXV 538
++ R+ +G+V + R+ + M L +P D Q CT +
Sbjct: 132 HGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEI 179
>S82612-1|AAB37533.2| 478|Homo sapiens 5-hydroxytryptamine type 3AS
receptor subunit protein.
Length = 478
Score = 41.1 bits (92), Expect = 0.005
Identities = 22/101 (21%), Positives = 44/101 (43%), Gaps = 1/101 (0%)
Frame = +2
Query: 230 NIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPNVVLLNAAATTAG 406
N+ E + + W D+ L WN ++ T L + ++ +W P++++
Sbjct: 72 NVDEKNQVLTTYIWYRQYWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINELVDVGKS 131
Query: 407 DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCT 529
+ + G V K L + T S+ + N+P D+Q C+
Sbjct: 132 PNIPYVYIRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCS 172
>X52009-1|CAA36258.1| 449|Homo sapiens inhibitory glycine receptor
protein.
Length = 449
Score = 40.7 bits (91), Expect = 0.007
Identities = 27/103 (26%), Positives = 47/103 (45%), Gaps = 4/103 (3%)
Frame = +2
Query: 230 NIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERLWRPNVVLLNAAATTAG 406
+I E+ R+ L+ W D RL++N S + +W+P++ N
Sbjct: 78 SIAETTMDYRVNIFLRQQWNDPRLAYNEYPDDSLDLDPSMLDSIWKPDLFFANEKGAHFH 137
Query: 407 DYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTC 526
+ R+S NG+V + R+ ++ M L N+P D+QTC
Sbjct: 138 EITTDNKLLRISRNGNVLYSIRITLTLACPMDLKNFPMDVQTC 180
>D49394-1|BAA08387.1| 478|Homo sapiens serotonin 5-HT3 receptor
protein.
Length = 478
Score = 40.7 bits (91), Expect = 0.007
Identities = 22/101 (21%), Positives = 44/101 (43%), Gaps = 1/101 (0%)
Frame = +2
Query: 230 NIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPNVVLLNAAATTAG 406
N+ E + + W D+ L WN ++ T L + ++ +W P++++
Sbjct: 72 NVDEKNQVLTTYIWYRQYWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKS 131
Query: 407 DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCT 529
+ + G V K L + T S+ + N+P D+Q C+
Sbjct: 132 PNIPYVYIRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCS 172
>BT007204-1|AAP35868.1| 484|Homo sapiens 5-hydroxytryptamine
(serotonin) receptor 3A protein.
Length = 484
Score = 40.7 bits (91), Expect = 0.007
Identities = 22/101 (21%), Positives = 44/101 (43%), Gaps = 1/101 (0%)
Frame = +2
Query: 230 NIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPNVVLLNAAATTAG 406
N+ E + + W D+ L WN ++ T L + ++ +W P++++
Sbjct: 78 NVDEKNQVLTTYIWYRQYWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKS 137
Query: 407 DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCT 529
+ + G V K L + T S+ + N+P D+Q C+
Sbjct: 138 PNIPYVYIRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCS 178
>BC004453-1|AAH04453.2| 478|Homo sapiens 5-hydroxytryptamine
(serotonin) receptor 3A protein.
Length = 478
Score = 40.7 bits (91), Expect = 0.007
Identities = 22/101 (21%), Positives = 44/101 (43%), Gaps = 1/101 (0%)
Frame = +2
Query: 230 NIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPNVVLLNAAATTAG 406
N+ E + + W D+ L WN ++ T L + ++ +W P++++
Sbjct: 72 NVDEKNQVLTTYIWYRQYWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKS 131
Query: 407 DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCT 529
+ + G V K L + T S+ + N+P D+Q C+
Sbjct: 132 PNIPYVYIRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCS 172
>BC002354-1|AAH02354.1| 478|Homo sapiens 5-hydroxytryptamine
(serotonin) receptor 3A protein.
Length = 478
Score = 40.7 bits (91), Expect = 0.007
Identities = 22/101 (21%), Positives = 44/101 (43%), Gaps = 1/101 (0%)
Frame = +2
Query: 230 NIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPNVVLLNAAATTAG 406
N+ E + + W D+ L WN ++ T L + ++ +W P++++
Sbjct: 72 NVDEKNQVLTTYIWYRQYWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKS 131
Query: 407 DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCT 529
+ + G V K L + T S+ + N+P D+Q C+
Sbjct: 132 PNIPYVYIRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCS 172
>AJ005205-1|CAA06442.3| 478|Homo sapiens serotonin 3 receptor
protein.
Length = 478
Score = 40.7 bits (91), Expect = 0.007
Identities = 22/101 (21%), Positives = 44/101 (43%), Gaps = 1/101 (0%)
Frame = +2
Query: 230 NIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPNVVLLNAAATTAG 406
N+ E + + W D+ L WN ++ T L + ++ +W P++++
Sbjct: 72 NVDEKNQVLTTYIWYRQYWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKS 131
Query: 407 DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCT 529
+ + G V K L + T S+ + N+P D+Q C+
Sbjct: 132 PNIPYVYIRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCS 172
>AJ003080-1|CAA05853.1| 238|Homo sapiens serotonin receptor
protein.
Length = 238
Score = 40.7 bits (91), Expect = 0.007
Identities = 22/101 (21%), Positives = 44/101 (43%), Gaps = 1/101 (0%)
Frame = +2
Query: 230 NIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPNVVLLNAAATTAG 406
N+ E + + W D+ L WN ++ T L + ++ +W P++++
Sbjct: 72 NVDEKNQVLTTYIWYRQYWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKS 131
Query: 407 DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCT 529
+ + G V K L + T S+ + N+P D+Q C+
Sbjct: 132 PNIPYVYIRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCS 172
>AJ003079-1|CAA05852.1| 478|Homo sapiens 5-hydroxytryptamine3
receptor protein.
Length = 478
Score = 40.7 bits (91), Expect = 0.007
Identities = 22/101 (21%), Positives = 44/101 (43%), Gaps = 1/101 (0%)
Frame = +2
Query: 230 NIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPNVVLLNAAATTAG 406
N+ E + + W D+ L WN ++ T L + ++ +W P++++
Sbjct: 72 NVDEKNQVLTTYIWYRQYWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKS 131
Query: 407 DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCT 529
+ + G V K L + T S+ + N+P D+Q C+
Sbjct: 132 PNIPYVYIRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCS 172
>AJ003078-1|CAA05851.1| 510|Homo sapiens serotonin receptor
protein.
Length = 510
Score = 40.7 bits (91), Expect = 0.007
Identities = 22/101 (21%), Positives = 44/101 (43%), Gaps = 1/101 (0%)
Frame = +2
Query: 230 NIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPNVVLLNAAATTAG 406
N+ E + + W D+ L WN ++ T L + ++ +W P++++
Sbjct: 72 NVDEKNQVLTTYIWYRQYWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKS 131
Query: 407 DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCT 529
+ + G V K L + T S+ + N+P D+Q C+
Sbjct: 132 PNIPYVYIRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCS 172
>AF498984-1|AAM21131.1| 478|Homo sapiens 5-hydroxytryptamine
receptor 3A protein.
Length = 478
Score = 40.7 bits (91), Expect = 0.007
Identities = 22/101 (21%), Positives = 44/101 (43%), Gaps = 1/101 (0%)
Frame = +2
Query: 230 NIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPNVVLLNAAATTAG 406
N+ E + + W D+ L WN ++ T L + ++ +W P++++
Sbjct: 72 NVDEKNQVLTTYIWYRQYWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKS 131
Query: 407 DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCT 529
+ + G V K L + T S+ + N+P D+Q C+
Sbjct: 132 PNIPYVYIRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCS 172
>Z23141-1|CAA80672.1| 479|Homo sapiens cholinergic receptor,
nicotinic, alpha polypeptide 7 protein.
Length = 479
Score = 40.3 bits (90), Expect = 0.009
Identities = 22/87 (25%), Positives = 42/87 (48%), Gaps = 2/87 (2%)
Frame = +2
Query: 272 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPNVVLLNAA-ATTAGDYALRARVSNNGS 445
LQM+W D L WN E+ G T ++W+P+++L N+A + V+++G
Sbjct: 55 LQMSWTDHYLQWNVSEYPGVKTVRFPDGQIWKPDILLYNSADERFDATFHTNVLVNSSGH 114
Query: 446 VSWIKRLDISTPISMQLDNWPNDMQTC 526
++ + + + +P D+Q C
Sbjct: 115 CQYLPPGIFKSSCYIDVRWFPFDVQHC 141
>Y08420-1|CAA69697.1| 502|Homo sapiens nicotinic acetylcholine
receptor alpha7 subunit precursor protein.
Length = 502
Score = 40.3 bits (90), Expect = 0.009
Identities = 22/87 (25%), Positives = 42/87 (48%), Gaps = 2/87 (2%)
Frame = +2
Query: 272 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPNVVLLNAA-ATTAGDYALRARVSNNGS 445
LQM+W D L WN E+ G T ++W+P+++L N+A + V+++G
Sbjct: 78 LQMSWTDHYLQWNVSEYPGVKTVRFPDGQIWKPDILLYNSADERFDATFHTNVLVNSSGH 137
Query: 446 VSWIKRLDISTPISMQLDNWPNDMQTC 526
++ + + + +P D+Q C
Sbjct: 138 CQYLPPGIFKSSCYIDVRWFPFDVQHC 164
>X70297-1|CAA49778.1| 502|Homo sapiens neuronal nicotinic
acetylocholine receptor alpha-7 subunit protein.
Length = 502
Score = 40.3 bits (90), Expect = 0.009
Identities = 22/87 (25%), Positives = 42/87 (48%), Gaps = 2/87 (2%)
Frame = +2
Query: 272 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPNVVLLNAA-ATTAGDYALRARVSNNGS 445
LQM+W D L WN E+ G T ++W+P+++L N+A + V+++G
Sbjct: 78 LQMSWTDHYLQWNVSEYPGVKTVRFPDGQIWKPDILLYNSADERFDATFHTNVLVNSSGH 137
Query: 446 VSWIKRLDISTPISMQLDNWPNDMQTC 526
++ + + + +P D+Q C
Sbjct: 138 CQYLPPGIFKSSCYIDVRWFPFDVQHC 164
>U95367-1|AAC51357.1| 440|Homo sapiens GABA-A receptor pi subunit
protein.
Length = 440
Score = 40.3 bits (90), Expect = 0.009
Identities = 37/148 (25%), Positives = 69/148 (46%), Gaps = 9/148 (6%)
Frame = +2
Query: 110 ECENATSLSLM-IDSLLATYDRESPPD---SKIVVNLTLHLRH-ANIRESESTVRILADL 274
E + LSL ++L A Y++ P+ + + LTL + ++I ES L
Sbjct: 29 EVGRSDKLSLPGFENLTAGYNKFLRPNFGGEPVQIALTLDIASISSISESNMDYTATIYL 88
Query: 275 QMNWIDKRLSWNAGE-WGCSTWLVSSERLWRPNVVLLNAAATTAGDYALR---ARVSNNG 442
+ W+D+RL + + + LV E LW P+ ++ + + + + R+ +NG
Sbjct: 89 RQRWMDQRLVFEGNKSFTLDARLV--EFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNG 146
Query: 443 SVSWIKRLDISTPISMQLDNWPNDMQTC 526
+V + R+ + +M L +P D QTC
Sbjct: 147 TVLYALRITTTVACNMDLSKYPMDTQTC 174
>U62436-1|AAB40114.1| 502|Homo sapiens nicotinic acetylcholine
receptor alpha7 subunit precursor protein.
Length = 502
Score = 40.3 bits (90), Expect = 0.009
Identities = 22/87 (25%), Positives = 42/87 (48%), Gaps = 2/87 (2%)
Frame = +2
Query: 272 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPNVVLLNAA-ATTAGDYALRARVSNNGS 445
LQM+W D L WN E+ G T ++W+P+++L N+A + V+++G
Sbjct: 78 LQMSWTDHYLQWNVSEYPGVKTVRFPDGQIWKPDILLYNSADERFDATFHTNVLVNSSGH 137
Query: 446 VSWIKRLDISTPISMQLDNWPNDMQTC 526
++ + + + +P D+Q C
Sbjct: 138 CQYLPPGIFKSSCYIDVRWFPFDVQHC 164
>BC109106-1|AAI09107.1| 440|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, pi protein.
Length = 440
Score = 40.3 bits (90), Expect = 0.009
Identities = 37/148 (25%), Positives = 69/148 (46%), Gaps = 9/148 (6%)
Frame = +2
Query: 110 ECENATSLSLM-IDSLLATYDRESPPD---SKIVVNLTLHLRH-ANIRESESTVRILADL 274
E + LSL ++L A Y++ P+ + + LTL + ++I ES L
Sbjct: 29 EVGRSDKLSLPGFENLTAGYNKFLRPNFGGEPVQIALTLDIASISSISESNMDYTATIYL 88
Query: 275 QMNWIDKRLSWNAGE-WGCSTWLVSSERLWRPNVVLLNAAATTAGDYALR---ARVSNNG 442
+ W+D+RL + + + LV E LW P+ ++ + + + + R+ +NG
Sbjct: 89 RQRWMDQRLVFEGNKSFTLDARLV--EFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNG 146
Query: 443 SVSWIKRLDISTPISMQLDNWPNDMQTC 526
+V + R+ + +M L +P D QTC
Sbjct: 147 TVLYALRITTTVACNMDLSKYPMDTQTC 174
>BC109105-1|AAI09106.1| 440|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, pi protein.
Length = 440
Score = 40.3 bits (90), Expect = 0.009
Identities = 37/148 (25%), Positives = 69/148 (46%), Gaps = 9/148 (6%)
Frame = +2
Query: 110 ECENATSLSLM-IDSLLATYDRESPPD---SKIVVNLTLHLRH-ANIRESESTVRILADL 274
E + LSL ++L A Y++ P+ + + LTL + ++I ES L
Sbjct: 29 EVGRSDKLSLPGFENLTAGYNKFLRPNFGGEPVQIALTLDIASISSISESNMDYTATIYL 88
Query: 275 QMNWIDKRLSWNAGE-WGCSTWLVSSERLWRPNVVLLNAAATTAGDYALR---ARVSNNG 442
+ W+D+RL + + + LV E LW P+ ++ + + + + R+ +NG
Sbjct: 89 RQRWMDQRLVFEGNKSFTLDARLV--EFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNG 146
Query: 443 SVSWIKRLDISTPISMQLDNWPNDMQTC 526
+V + R+ + +M L +P D QTC
Sbjct: 147 TVLYALRITTTVACNMDLSKYPMDTQTC 174
>BC074865-1|AAH74865.1| 440|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, pi protein.
Length = 440
Score = 40.3 bits (90), Expect = 0.009
Identities = 37/148 (25%), Positives = 69/148 (46%), Gaps = 9/148 (6%)
Frame = +2
Query: 110 ECENATSLSLM-IDSLLATYDRESPPD---SKIVVNLTLHLRH-ANIRESESTVRILADL 274
E + LSL ++L A Y++ P+ + + LTL + ++I ES L
Sbjct: 29 EVGRSDKLSLPGFENLTAGYNKFLRPNFGGEPVQIALTLDIASISSISESNMDYTATIYL 88
Query: 275 QMNWIDKRLSWNAGE-WGCSTWLVSSERLWRPNVVLLNAAATTAGDYALR---ARVSNNG 442
+ W+D+RL + + + LV E LW P+ ++ + + + + R+ +NG
Sbjct: 89 RQRWMDQRLVFEGNKSFTLDARLV--EFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNG 146
Query: 443 SVSWIKRLDISTPISMQLDNWPNDMQTC 526
+V + R+ + +M L +P D QTC
Sbjct: 147 TVLYALRITTTVACNMDLSKYPMDTQTC 174
>BC074810-1|AAH74810.1| 440|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, pi protein.
Length = 440
Score = 40.3 bits (90), Expect = 0.009
Identities = 37/148 (25%), Positives = 69/148 (46%), Gaps = 9/148 (6%)
Frame = +2
Query: 110 ECENATSLSLM-IDSLLATYDRESPPD---SKIVVNLTLHLRH-ANIRESESTVRILADL 274
E + LSL ++L A Y++ P+ + + LTL + ++I ES L
Sbjct: 29 EVGRSDKLSLPGFENLTAGYNKFLRPNFGGEPVQIALTLDIASISSISESNMDYTATIYL 88
Query: 275 QMNWIDKRLSWNAGE-WGCSTWLVSSERLWRPNVVLLNAAATTAGDYALR---ARVSNNG 442
+ W+D+RL + + + LV E LW P+ ++ + + + + R+ +NG
Sbjct: 89 RQRWMDQRLVFEGNKSFTLDARLV--EFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNG 146
Query: 443 SVSWIKRLDISTPISMQLDNWPNDMQTC 526
+V + R+ + +M L +P D QTC
Sbjct: 147 TVLYALRITTTVACNMDLSKYPMDTQTC 174
>AJ586911-1|CAE52911.1| 502|Homo sapiens nicotinic acetylcholine
alpha-7 subunit protein.
Length = 502
Score = 40.3 bits (90), Expect = 0.009
Identities = 22/87 (25%), Positives = 42/87 (48%), Gaps = 2/87 (2%)
Frame = +2
Query: 272 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPNVVLLNAA-ATTAGDYALRARVSNNGS 445
LQM+W D L WN E+ G T ++W+P+++L N+A + V+++G
Sbjct: 78 LQMSWTDHYLQWNVSEYPGVKTVRFPDGQIWKPDILLYNSADERFDATFHTNVLVNSSGH 137
Query: 446 VSWIKRLDISTPISMQLDNWPNDMQTC 526
++ + + + +P D+Q C
Sbjct: 138 CQYLPPGIFKSSCYIDVRWFPFDVQHC 164
>AF009702-1|AAC24194.1| 440|Homo sapiens GABA-A receptor pi subunit
protein.
Length = 440
Score = 40.3 bits (90), Expect = 0.009
Identities = 37/148 (25%), Positives = 69/148 (46%), Gaps = 9/148 (6%)
Frame = +2
Query: 110 ECENATSLSLM-IDSLLATYDRESPPD---SKIVVNLTLHLRH-ANIRESESTVRILADL 274
E + LSL ++L A Y++ P+ + + LTL + ++I ES L
Sbjct: 29 EVGRSDKLSLPGFENLTAGYNKFLRPNFGGEPVQIALTLDIASISSISESNMDYTATIYL 88
Query: 275 QMNWIDKRLSWNAGE-WGCSTWLVSSERLWRPNVVLLNAAATTAGDYALR---ARVSNNG 442
+ W+D+RL + + + LV E LW P+ ++ + + + + R+ +NG
Sbjct: 89 RQRWMDQRLVFEGNKSFTLDARLV--EFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNG 146
Query: 443 SVSWIKRLDISTPISMQLDNWPNDMQTC 526
+V + R+ + +M L +P D QTC
Sbjct: 147 TVLYALRITTTVACNMDLSKYPMDTQTC 174
>Z93848-1|CAI41994.1| 376|Homo sapiens glycine receptor, alpha 4
protein.
Length = 376
Score = 39.9 bits (89), Expect = 0.012
Identities = 34/130 (26%), Positives = 57/130 (43%), Gaps = 8/130 (6%)
Frame = +2
Query: 164 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 331
YD P+ K VN+T ++ ++I ++ R+ L+ W D RLS+
Sbjct: 17 YDARIRPNFKGPPVNVTCNIFINSFSSITKTTMDYRVNVFLRQQWNDPRLSYREYPDDSL 76
Query: 332 TWLVSS-ERLWRPNVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLD 499
S + +W+P++ N + R+ NG+V + RL + M L
Sbjct: 77 DLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLILSCLMDLK 136
Query: 500 NWPNDMQTCT 529
N+P D+QTCT
Sbjct: 137 NFPMDIQTCT 146
>AL049610-1|CAI42158.1| 376|Homo sapiens glycine receptor, alpha 4
protein.
Length = 376
Score = 39.9 bits (89), Expect = 0.012
Identities = 34/130 (26%), Positives = 57/130 (43%), Gaps = 8/130 (6%)
Frame = +2
Query: 164 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 331
YD P+ K VN+T ++ ++I ++ R+ L+ W D RLS+
Sbjct: 17 YDARIRPNFKGPPVNVTCNIFINSFSSITKTTMDYRVNVFLRQQWNDPRLSYREYPDDSL 76
Query: 332 TWLVSS-ERLWRPNVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLD 499
S + +W+P++ N + R+ NG+V + RL + M L
Sbjct: 77 DLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLILSCLMDLK 136
Query: 500 NWPNDMQTCT 529
N+P D+QTCT
Sbjct: 137 NFPMDIQTCT 146
>U93917-1|AAC39917.1| 449|Homo sapiens glycine receptor alpha 3
subunit protein.
Length = 449
Score = 39.5 bits (88), Expect = 0.016
Identities = 33/129 (25%), Positives = 57/129 (44%), Gaps = 8/129 (6%)
Frame = +2
Query: 164 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 331
YD P+ K VN+T ++ +I E+ R+ L+ W D RL+++
Sbjct: 57 YDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPDDSL 116
Query: 332 TWLVSS-ERLWRPNVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLD 499
S + +W+P++ N + R+ NG+V + RL ++ M L
Sbjct: 117 DLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLK 176
Query: 500 NWPNDMQTC 526
N+P D+QTC
Sbjct: 177 NFPMDVQTC 185
>U40583-1|AAA83561.1| 502|Homo sapiens alpha 7 neuronal nicotinic
acetylcholine receptor protein.
Length = 502
Score = 39.5 bits (88), Expect = 0.016
Identities = 16/41 (39%), Positives = 25/41 (60%), Gaps = 1/41 (2%)
Frame = +2
Query: 272 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPNVVLLNAA 391
LQM+W D L WN E+ G T ++W+P+++L N+A
Sbjct: 78 LQMSWTDHYLQWNVSEYPGVKTVRFPDGQIWKPDILLYNSA 118
>BC036086-1|AAH36086.1| 464|Homo sapiens glycine receptor, alpha 3
protein.
Length = 464
Score = 39.5 bits (88), Expect = 0.016
Identities = 33/129 (25%), Positives = 57/129 (44%), Gaps = 8/129 (6%)
Frame = +2
Query: 164 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 331
YD P+ K VN+T ++ +I E+ R+ L+ W D RL+++
Sbjct: 57 YDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPDDSL 116
Query: 332 TWLVSS-ERLWRPNVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLD 499
S + +W+P++ N + R+ NG+V + RL ++ M L
Sbjct: 117 DLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLK 176
Query: 500 NWPNDMQTC 526
N+P D+QTC
Sbjct: 177 NFPMDVQTC 185
>AF385585-1|AAK68111.1| 502|Homo sapiens nicotinic cholinergic
receptor alpha 7 protein.
Length = 502
Score = 39.5 bits (88), Expect = 0.016
Identities = 16/41 (39%), Positives = 25/41 (60%), Gaps = 1/41 (2%)
Frame = +2
Query: 272 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPNVVLLNAA 391
LQM+W D L WN E+ G T ++W+P+++L N+A
Sbjct: 78 LQMSWTDHYLQWNVSEYPGVKTVRFPDGQIWKPDILLYNSA 118
>AF017724-1|AAC39919.1| 465|Homo sapiens glycine receptor alpha 3
subunit protein.
Length = 465
Score = 39.5 bits (88), Expect = 0.016
Identities = 33/129 (25%), Positives = 57/129 (44%), Gaps = 8/129 (6%)
Frame = +2
Query: 164 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 331
YD P+ K VN+T ++ +I E+ R+ L+ W D RL+++
Sbjct: 57 YDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPDDSL 116
Query: 332 TWLVSS-ERLWRPNVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLD 499
S + +W+P++ N + R+ NG+V + RL ++ M L
Sbjct: 117 DLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLK 176
Query: 500 NWPNDMQTC 526
N+P D+QTC
Sbjct: 177 NFPMDVQTC 185
>BC114967-1|AAI14968.1| 366|Homo sapiens GLRA1 protein protein.
Length = 366
Score = 38.3 bits (85), Expect = 0.036
Identities = 25/94 (26%), Positives = 43/94 (45%), Gaps = 4/94 (4%)
Frame = +2
Query: 257 RILADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERLWRPNVVLLNAAATTAGDYALR---A 424
R+ L+ W D RL++N S + +W+P++ N +
Sbjct: 4 RVNIFLRQQWNDPRLAYNEYPDDSLDLDPSMLDSIWKPDLFFANEKGAHFHEITTDNKLL 63
Query: 425 RVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTC 526
R+S NG+V + R+ ++ M L N+P D+QTC
Sbjct: 64 RISRNGNVLYSIRITLTLACPMDLKNFPMDVQTC 97
>BC074795-1|AAH74795.1| 467|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, gamma 2 protein.
Length = 467
Score = 37.5 bits (83), Expect = 0.063
Identities = 32/141 (22%), Positives = 61/141 (43%), Gaps = 9/141 (6%)
Frame = +2
Query: 131 LSLMIDSLLATYDRESPPDSKI---VVNLTLHLRH---ANIRESESTVRILADLQMNWID 292
+++++++LL YD + PD + +++ +++ N E T+ I W D
Sbjct: 66 VTVILNNLLEGYDNKLRPDIGVKPTLIHTDMYVNSIGPVNAINMEYTIDIF--FAQTWYD 123
Query: 293 KRLSWNAGEWGCSTWLVSSERLWRPNVVLLNAAATTAGDYAL---RARVSNNGSVSWIKR 463
+RL +N+ ++W P+ N+ A R+ N+G V + R
Sbjct: 124 RRLKFNSTIKVLRLNSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYTLR 183
Query: 464 LDISTPISMQLDNWPNDMQTC 526
L I +QL N+P D +C
Sbjct: 184 LTIDAECQLQLHNFPMDEHSC 204
>BC069348-1|AAH69348.1| 467|Homo sapiens gamma-aminobutyric acid A
receptor, gamma 2, isoform 2 precursor protein.
Length = 467
Score = 37.5 bits (83), Expect = 0.063
Identities = 32/141 (22%), Positives = 61/141 (43%), Gaps = 9/141 (6%)
Frame = +2
Query: 131 LSLMIDSLLATYDRESPPDSKI---VVNLTLHLRH---ANIRESESTVRILADLQMNWID 292
+++++++LL YD + PD + +++ +++ N E T+ I W D
Sbjct: 66 VTVILNNLLEGYDNKLRPDIGVKPTLIHTDMYVNSIGPVNAINMEYTIDIF--FAQTWYD 123
Query: 293 KRLSWNAGEWGCSTWLVSSERLWRPNVVLLNAAATTAGDYAL---RARVSNNGSVSWIKR 463
+RL +N+ ++W P+ N+ A R+ N+G V + R
Sbjct: 124 RRLKFNSTIKVLRLNSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYTLR 183
Query: 464 LDISTPISMQLDNWPNDMQTC 526
L I +QL N+P D +C
Sbjct: 184 LTIDAECQLQLHNFPMDEHSC 204
>BC059389-1|AAH59389.1| 475|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, gamma 2 protein.
Length = 475
Score = 37.5 bits (83), Expect = 0.063
Identities = 32/141 (22%), Positives = 61/141 (43%), Gaps = 9/141 (6%)
Frame = +2
Query: 131 LSLMIDSLLATYDRESPPDSKI---VVNLTLHLRH---ANIRESESTVRILADLQMNWID 292
+++++++LL YD + PD + +++ +++ N E T+ I W D
Sbjct: 66 VTVILNNLLEGYDNKLRPDIGVKPTLIHTDMYVNSIGPVNAINMEYTIDIF--FAQTWYD 123
Query: 293 KRLSWNAGEWGCSTWLVSSERLWRPNVVLLNAAATTAGDYAL---RARVSNNGSVSWIKR 463
+RL +N+ ++W P+ N+ A R+ N+G V + R
Sbjct: 124 RRLKFNSTIKVLRLNSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYTLR 183
Query: 464 LDISTPISMQLDNWPNDMQTC 526
L I +QL N+P D +C
Sbjct: 184 LTIDAECQLQLHNFPMDEHSC 204
>AF165124-1|AAD50273.1| 467|Homo sapiens gamma-aminobutyric acid A
receptor gamma 2 protein.
Length = 467
Score = 37.5 bits (83), Expect = 0.063
Identities = 32/141 (22%), Positives = 61/141 (43%), Gaps = 9/141 (6%)
Frame = +2
Query: 131 LSLMIDSLLATYDRESPPDSKI---VVNLTLHLRH---ANIRESESTVRILADLQMNWID 292
+++++++LL YD + PD + +++ +++ N E T+ I W D
Sbjct: 66 VTVILNNLLEGYDNKLRPDIGVKPTLIHTDMYVNSIGPVNAINMEYTIDIF--FAQTWYD 123
Query: 293 KRLSWNAGEWGCSTWLVSSERLWRPNVVLLNAAATTAGDYAL---RARVSNNGSVSWIKR 463
+RL +N+ ++W P+ N+ A R+ N+G V + R
Sbjct: 124 RRLKFNSTIKVLRLNSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYTLR 183
Query: 464 LDISTPISMQLDNWPNDMQTC 526
L I +QL N+P D +C
Sbjct: 184 LTIDAECQLQLHNFPMDEHSC 204
>S81944-1|AAB36480.1| 453|Homo sapiens gamma-aminobutyric acid type
A receptor alpha 6 subunit protein.
Length = 453
Score = 37.1 bits (82), Expect = 0.083
Identities = 30/140 (21%), Positives = 58/140 (41%), Gaps = 7/140 (5%)
Frame = +2
Query: 128 SLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESESTVRILADLQMNWIDK 295
++S ++D+LL YD P + V +++ + + E + + W D+
Sbjct: 31 NVSRILDNLLEGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTDE 90
Query: 296 RLSWNAGEWGCSTWLVSSERLWRPNVVLLNAAATTAGDYALRA---RVSNNGSVSWIKRL 466
RL + S + ++W P+ N + A + R+ NG++ + RL
Sbjct: 91 RLKFGGPTEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTMRL 150
Query: 467 DISTPISMQLDNWPNDMQTC 526
I+ M+L N+P D C
Sbjct: 151 TINADCPMRLVNFPMDGHAC 170
>BC099641-1|AAH99641.1| 453|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 6 protein.
Length = 453
Score = 37.1 bits (82), Expect = 0.083
Identities = 30/140 (21%), Positives = 58/140 (41%), Gaps = 7/140 (5%)
Frame = +2
Query: 128 SLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESESTVRILADLQMNWIDK 295
++S ++D+LL YD P + V +++ + + E + + W D+
Sbjct: 31 NVSRILDNLLEGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTDE 90
Query: 296 RLSWNAGEWGCSTWLVSSERLWRPNVVLLNAAATTAGDYALRA---RVSNNGSVSWIKRL 466
RL + S + ++W P+ N + A + R+ NG++ + RL
Sbjct: 91 RLKFGGPTEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTMRL 150
Query: 467 DISTPISMQLDNWPNDMQTC 526
I+ M+L N+P D C
Sbjct: 151 TINADCPMRLVNFPMDGHAC 170
>BC099640-1|AAH99640.1| 453|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 6 protein.
Length = 453
Score = 37.1 bits (82), Expect = 0.083
Identities = 30/140 (21%), Positives = 58/140 (41%), Gaps = 7/140 (5%)
Frame = +2
Query: 128 SLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESESTVRILADLQMNWIDK 295
++S ++D+LL YD P + V +++ + + E + + W D+
Sbjct: 31 NVSRILDNLLEGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTDE 90
Query: 296 RLSWNAGEWGCSTWLVSSERLWRPNVVLLNAAATTAGDYALRA---RVSNNGSVSWIKRL 466
RL + S + ++W P+ N + A + R+ NG++ + RL
Sbjct: 91 RLKFGGPTEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTMRL 150
Query: 467 DISTPISMQLDNWPNDMQTC 526
I+ M+L N+P D C
Sbjct: 151 TINADCPMRLVNFPMDGHAC 170
>BC096242-1|AAH96242.1| 453|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 6 protein.
Length = 453
Score = 37.1 bits (82), Expect = 0.083
Identities = 30/140 (21%), Positives = 58/140 (41%), Gaps = 7/140 (5%)
Frame = +2
Query: 128 SLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESESTVRILADLQMNWIDK 295
++S ++D+LL YD P + V +++ + + E + + W D+
Sbjct: 31 NVSRILDNLLEGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTDE 90
Query: 296 RLSWNAGEWGCSTWLVSSERLWRPNVVLLNAAATTAGDYALRA---RVSNNGSVSWIKRL 466
RL + S + ++W P+ N + A + R+ NG++ + RL
Sbjct: 91 RLKFGGPTEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTMRL 150
Query: 467 DISTPISMQLDNWPNDMQTC 526
I+ M+L N+P D C
Sbjct: 151 TINADCPMRLVNFPMDGHAC 170
>BC096241-1|AAH96241.1| 453|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 6 protein.
Length = 453
Score = 37.1 bits (82), Expect = 0.083
Identities = 30/140 (21%), Positives = 58/140 (41%), Gaps = 7/140 (5%)
Frame = +2
Query: 128 SLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESESTVRILADLQMNWIDK 295
++S ++D+LL YD P + V +++ + + E + + W D+
Sbjct: 31 NVSRILDNLLEGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTDE 90
Query: 296 RLSWNAGEWGCSTWLVSSERLWRPNVVLLNAAATTAGDYALRA---RVSNNGSVSWIKRL 466
RL + S + ++W P+ N + A + R+ NG++ + RL
Sbjct: 91 RLKFGGPTEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTMRL 150
Query: 467 DISTPISMQLDNWPNDMQTC 526
I+ M+L N+P D C
Sbjct: 151 TINADCPMRLVNFPMDGHAC 170
>X15376-1|CAA33437.1| 467|Homo sapiens GABA-A receptor gamma 2
subunit protein.
Length = 467
Score = 36.7 bits (81), Expect = 0.11
Identities = 34/141 (24%), Positives = 63/141 (44%), Gaps = 9/141 (6%)
Frame = +2
Query: 131 LSLMIDSLLATYDRESPPDSKI---VVNLTLHLRH---ANIRESESTVRILADLQMNWID 292
+++++++LL YD + PD + +++ +++ N E T+ I QM W D
Sbjct: 66 VTVILNNLLEGYDNKLRPDIGVKPTLIHTDMYVNSIGPVNAINMEYTIDIFF-AQM-WYD 123
Query: 293 KRLSWNAGEWGCSTWLVSSERLWRPNVVLLNAAATTAGDYAL---RARVSNNGSVSWIKR 463
+RL +N+ ++W P+ N+ A R+ N+G V + R
Sbjct: 124 RRLKFNSTIKVLRLNSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYSLR 183
Query: 464 LDISTPISMQLDNWPNDMQTC 526
L I +QL N+P D +C
Sbjct: 184 LTIDAECQLQLHNFPMDEHSC 204
>BC031087-1|AAH31087.1| 465|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, gamma 1 protein.
Length = 465
Score = 35.9 bits (79), Expect = 0.19
Identities = 33/141 (23%), Positives = 61/141 (43%), Gaps = 9/141 (6%)
Frame = +2
Query: 131 LSLMIDSLLATYDRESPPDSKI---VVNLTLHLRHANIRES---ESTVRILADLQMNWID 292
++ +++SLL YD + PD + V+ +++ + E T+ I+ W D
Sbjct: 64 ITQILNSLLQGYDNKLRPDIGVRPTVIETDVYVNSIGPVDPINMEYTIDII--FAQTWFD 121
Query: 293 KRLSWNAGEWGCSTWLVSSERLWRPNVVLLNAAATTAGDYALR---ARVSNNGSVSWIKR 463
RL +N+ ++W P+ N+ + A R+ N+G V + R
Sbjct: 122 SRLKFNSTMKVLMLNSNMVGKIWIPDTFFRNSRKSDAHWITTPNRLLRIWNDGRVLYTLR 181
Query: 464 LDISTPISMQLDNWPNDMQTC 526
L I+ +QL N+P D +C
Sbjct: 182 LTINAECYLQLHNFPMDEHSC 202
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 124,103,389
Number of Sequences: 237096
Number of extensions: 2784838
Number of successful extensions: 6557
Number of sequences better than 10.0: 151
Number of HSP's better than 10.0 without gapping: 6076
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 6486
length of database: 76,859,062
effective HSP length: 90
effective length of database: 55,520,422
effective search space used: 11104084400
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
- SilkBase 1999-2023 -