Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BmNP08_FL5_B03
(871 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
AJ306454-1|CAC34819.1| 497|Homo sapiens neuronal nicotinic acet... 69 2e-11
Y08416-1|CAA69693.1| 498|Homo sapiens nicotinic acetylcholine r... 67 9e-11
U62439-1|AAB40117.1| 498|Homo sapiens nicotinic acetylcholine r... 67 9e-11
U48861-1|AAA92123.1| 498|Homo sapiens beta 4 nicotinic acetylch... 67 9e-11
BC096082-1|AAH96082.1| 498|Homo sapiens cholinergic receptor, n... 67 9e-11
BC096080-1|AAH96080.1| 498|Homo sapiens cholinergic receptor, n... 67 9e-11
AF306329-1|AAL02062.1| 498|Homo sapiens neuronal nicotinic acet... 67 9e-11
X68275-1|CAA48336.1| 451|Homo sapiens nicotinic receptor beta 4... 63 1e-09
Y08417-1|CAA69694.1| 458|Homo sapiens nicotinic acetylcholine r... 62 3e-09
X67513-1|CAA47851.1| 423|Homo sapiens nicotinic acetylcholine ... 62 3e-09
U62438-1|AAB40116.1| 458|Homo sapiens nicotinic acetylcholine r... 62 3e-09
BC069788-1|AAH69788.1| 458|Homo sapiens cholinergic receptor, n... 62 3e-09
BC069703-1|AAH69703.1| 458|Homo sapiens cholinergic receptor, n... 62 3e-09
BC069681-1|AAH69681.1| 458|Homo sapiens cholinergic receptor, n... 62 3e-09
AF140765-1|AAD33063.1| 458|Homo sapiens neuronal acetylcholine ... 62 3e-09
Y16281-1|CAA76154.1| 529|Homo sapiens nicotinic acetylcholine r... 62 3e-09
Y08419-1|CAA69696.1| 468|Homo sapiens nicotinic acetylcholine r... 62 3e-09
U62434-1|AAB40112.1| 468|Homo sapiens nicotinic acetylcholine r... 62 3e-09
U62431-1|AAB40109.1| 529|Homo sapiens nicotinic acetylcholine r... 62 3e-09
BC033639-1|AAH33639.1| 468|Homo sapiens cholinergic receptor, n... 62 3e-09
AJ306481-1|CAC34820.1| 468|Homo sapiens neuronal nicotinic acet... 62 3e-09
Y16282-1|CAA76155.1| 494|Homo sapiens nicotinic acetylcholine r... 61 4e-09
X14830-1|CAA32939.1| 501|Homo sapiens protein ( Human mRNA for ... 61 4e-09
U62435-1|AAB40113.1| 494|Homo sapiens nicotinic acetylcholine r... 61 4e-09
BC014456-1|AAH14456.1| 494|Homo sapiens cholinergic receptor, n... 61 4e-09
BC011371-1|AAH11371.1| 501|Homo sapiens cholinergic receptor, n... 61 4e-09
AB079251-1|BAC06855.1| 494|Homo sapiens Nicotinic acetylcholine... 61 4e-09
Y08418-1|CAA69695.1| 503|Homo sapiens nicotinic acetylcholine r... 60 8e-09
X53559-1|CAA37625.1| 474|Homo sapiens neuronal nicotinic acetyl... 60 8e-09
U62432-1|AAB40110.1| 504|Homo sapiens nicotinic acetylcholine r... 60 8e-09
M83712-1|AAA58357.1| 468|Homo sapiens nicotinic receptor alpha ... 60 8e-09
M37981-1|AAA59942.1| 503|Homo sapiens neuronal nicotinic acetyl... 60 8e-09
BT006897-1|AAP35543.1| 505|Homo sapiens cholinergic receptor, n... 60 8e-09
BT006646-1|AAP35292.1| 489|Homo sapiens cholinergic receptor, n... 60 8e-09
BC098443-1|AAH98443.1| 504|Homo sapiens cholinergic receptor, n... 60 8e-09
BC006114-1|AAH06114.1| 489|Homo sapiens CHRNA3 protein protein. 60 8e-09
BC002996-1|AAH02996.1| 505|Homo sapiens cholinergic receptor, n... 60 8e-09
BC001642-1|AAH01642.1| 505|Homo sapiens cholinergic receptor, n... 60 8e-09
BC000513-1|AAH00513.1| 505|Homo sapiens cholinergic receptor, n... 60 8e-09
AJ007783-1|CAA07682.1| 504|Homo sapiens nicotinic acetylcholine... 60 8e-09
AF385584-1|AAK68110.1| 489|Homo sapiens nicotinic cholinergic r... 60 8e-09
BC023553-1|AAH23553.1| 501|Homo sapiens cholinergic receptor, n... 60 1e-08
X01715-1|CAA25861.1| 520|Homo sapiens acetylcholine receptor ga... 59 2e-08
AC092165-3|AAY24103.1| 520|Homo sapiens unknown protein. 59 2e-08
X66403-1|CAA47030.1| 493|Homo sapiens acetylcholine receptor ep... 58 3e-08
AF105999-1|AAD24503.1| 493|Homo sapiens acetylcholine receptor ... 58 3e-08
M86383-1|AAC84176.1| 502|Homo sapiens nicotinic acetylcholine r... 58 4e-08
Y08421-1|CAA69698.1| 627|Homo sapiens nicotinic acetylcholine r... 58 5e-08
X89741-1|CAA61893.1| 627|Homo sapiens neuronal acetylcholine re... 58 5e-08
X87629-1|CAA60959.1| 602|Homo sapiens nicotinic acetylcholine r... 58 5e-08
U62433-1|AAB40111.1| 627|Homo sapiens nicotinic acetylcholine r... 58 5e-08
L35901-1|AAA64743.1| 627|Homo sapiens nicotinic acetylcholine r... 58 5e-08
DQ093071-1|AAY88737.1| 627|Homo sapiens cholinergic receptor, n... 58 5e-08
BC096290-1|AAH96290.1| 627|Homo sapiens cholinergic receptor, n... 58 5e-08
Y00762-1|CAA68731.1| 457|Homo sapiens protein ( Human mRNA for ... 56 2e-07
X02502-1|CAA26344.1| 457|Homo sapiens acetylcholine receptor pr... 56 2e-07
S77094-1|AAD14247.1| 457|Homo sapiens nicotinic acetylcholine r... 56 2e-07
BC006314-1|AAH06314.1| 269|Homo sapiens CHRNA1 protein protein. 56 2e-07
AC018890-1|AAY14687.1| 457|Homo sapiens unknown protein. 56 2e-07
Y08415-1|CAA69692.1| 502|Homo sapiens nicotinic acetylcholine r... 56 2e-07
X53179-1|CAA37320.1| 502|Homo sapiens precursor peptide (AA -25... 56 2e-07
U62437-1|AAB40115.1| 502|Homo sapiens nicotinic acetylcholine r... 56 2e-07
DQ644022-1|ABG35128.1| 456|Homo sapiens 5-HT3 receptor subunit ... 56 2e-07
BC101185-1|AAI01186.1| 374|Homo sapiens HTR3E protein protein. 56 2e-07
BC101183-1|AAI01184.1| 471|Homo sapiens 5-hydroxytryptamine (se... 56 2e-07
BC101182-1|AAI01183.1| 471|Homo sapiens 5-hydroxytryptamine (se... 56 2e-07
BC075041-1|AAH75041.1| 502|Homo sapiens cholinergic receptor, n... 56 2e-07
BC075040-1|AAH75040.1| 502|Homo sapiens cholinergic receptor, n... 56 2e-07
AY159813-1|AAO38167.2| 471|Homo sapiens 5-hydroxytryptamine ser... 56 2e-07
AL592078-3|CAI16184.1| 502|Homo sapiens cholinergic receptor, n... 56 2e-07
AJ295237-1|CAC16144.1| 450|Homo sapiens neuronal nicotinic acet... 56 2e-07
AJ278118-1|CAC20435.1| 450|Homo sapiens neuronal nicotinic acet... 56 2e-07
AJ001935-1|CAA05108.1| 504|Homo sapiens CHRNB2 protein. 56 2e-07
AF327367-1|AAK14333.1| 450|Homo sapiens nicotinic acetylcholine... 56 2e-07
AF199235-1|AAG00795.2| 450|Homo sapiens nicotinic acetylcholine... 56 2e-07
AF077186-1|AAD45422.1| 502|Homo sapiens neuronal nicotinic acet... 56 2e-07
X55019-1|CAA38759.1| 517|Homo sapiens acetylcholine receptor de... 54 7e-07
BC131799-1|AAI31800.1| 447|Homo sapiens 5-hydroxytryptamine (se... 54 7e-07
BC093925-1|AAH93925.1| 517|Homo sapiens cholinergic receptor, n... 54 7e-07
BC093923-1|AAH93923.1| 517|Homo sapiens cholinergic receptor, n... 54 7e-07
AY349353-1|AAQ93477.1| 456|Homo sapiens 5-HT3c1 serotonin recep... 54 7e-07
AY349352-1|AAQ93476.1| 441|Homo sapiens 5-HT3c1 serotonin recep... 54 7e-07
AC092165-2|AAY24102.1| 517|Homo sapiens unknown protein. 54 7e-07
AF459285-1|AAL66182.1| 447|Homo sapiens 5-hydroxytryptamine rec... 54 9e-07
BC110597-1|AAI10598.1| 411|Homo sapiens ligand-gated ion channe... 52 4e-06
AF512521-1|AAO20969.1| 411|Homo sapiens ligand-gated ion channe... 52 4e-06
AB223030-1|BAE19924.1| 411|Homo sapiens ligand-gated ion-channe... 51 5e-06
L08485-1|AAA58490.1| 462|Homo sapiens GABA-benzodiazepine recep... 51 6e-06
BT009830-1|AAP88832.1| 462|Homo sapiens gamma-aminobutyric acid... 51 6e-06
BC113575-1|AAI13576.1| 479|Homo sapiens cholinergic receptor, n... 51 6e-06
BC113549-1|AAI13550.1| 479|Homo sapiens cholinergic receptor, n... 51 6e-06
BC113422-1|AAI13423.1| 462|Homo sapiens gamma-aminobutyric acid... 51 6e-06
BC111979-1|AAI11980.1| 462|Homo sapiens gamma-aminobutyric acid... 51 6e-06
AY123244-1|AAM74523.1| 479|Homo sapiens nicotinic acetylcholine... 51 6e-06
AJ243342-1|CAB65091.1| 479|Homo sapiens nicotinic acetylcholine... 51 6e-06
AF227732-1|AAF61920.1| 470|Homo sapiens nicotinic acetylcholine... 51 6e-06
AC118275-1|AAY40986.1| 479|Homo sapiens unknown protein. 51 6e-06
Z23141-1|CAA80672.1| 479|Homo sapiens cholinergic receptor, nic... 50 1e-05
Y08420-1|CAA69697.1| 502|Homo sapiens nicotinic acetylcholine r... 50 1e-05
X70297-1|CAA49778.1| 502|Homo sapiens neuronal nicotinic acetyl... 50 1e-05
U62436-1|AAB40114.1| 502|Homo sapiens nicotinic acetylcholine r... 50 1e-05
S82769-1|AAB39369.1| 467|Homo sapiens GABAA receptor gamma 3 su... 50 1e-05
AJ586911-1|CAE52911.1| 502|Homo sapiens nicotinic acetylcholine... 50 1e-05
AF269144-1|AAF99698.1| 467|Homo sapiens GABAA receptor gamma 3 ... 50 1e-05
AF228458-1|AAF63215.1| 449|Homo sapiens GABAA receptor gamma 3 ... 50 1e-05
BC028629-1|AAH28629.1| 492|Homo sapiens gamma-aminobutyric acid... 49 3e-05
U40583-1|AAA83561.1| 502|Homo sapiens alpha 7 neuronal nicotini... 48 3e-05
S62908-1|AAB27279.1| 492|Homo sapiens gamma-aminobutyric acidA ... 48 3e-05
BC111802-1|AAI11803.1| 465|Homo sapiens CHRNG protein protein. 48 3e-05
AF385585-1|AAK68111.1| 502|Homo sapiens nicotinic cholinergic r... 48 3e-05
AF166361-1|AAG12455.1| 492|Homo sapiens GABA receptor subunit a... 48 3e-05
AK122638-1|BAC85499.1| 266|Homo sapiens yte protein of 76kDa) (... 48 4e-05
U77731-2|AAB38273.1| 360|Homo sapiens glycine receptor alpha 2B... 47 8e-05
CR450343-1|CAG29339.1| 452|Homo sapiens GLRA2 protein. 47 8e-05
AY437084-1|AAR87843.1| 452|Homo sapiens glycine receptor alpha2... 47 8e-05
X52008-1|CAA36257.1| 452|Homo sapiens inhibitory glycine recept... 47 1e-04
U77731-1|AAB38272.1| 360|Homo sapiens glycine receptor alpha 2 ... 47 1e-04
S81944-1|AAB36480.1| 453|Homo sapiens gamma-aminobutyric acid t... 47 1e-04
BC099641-1|AAH99641.1| 453|Homo sapiens gamma-aminobutyric acid... 47 1e-04
BC099640-1|AAH99640.1| 453|Homo sapiens gamma-aminobutyric acid... 47 1e-04
BC096242-1|AAH96242.1| 453|Homo sapiens gamma-aminobutyric acid... 47 1e-04
BC096241-1|AAH96241.1| 453|Homo sapiens gamma-aminobutyric acid... 47 1e-04
BC032864-1|AAH32864.1| 452|Homo sapiens glycine receptor, alpha... 47 1e-04
AY437083-1|AAR87842.1| 452|Homo sapiens glycine receptor alpha2... 47 1e-04
AJ003080-1|CAA05853.1| 238|Homo sapiens serotonin receptor prot... 47 1e-04
AF053495-1|AAC35290.1| 452|Homo sapiens glycine receptor alpha ... 47 1e-04
U30461-1|AAB52519.1| 554|Homo sapiens GABAA receptor subunit al... 46 1e-04
S82612-1|AAB37533.2| 478|Homo sapiens 5-hydroxytryptamine type ... 46 1e-04
BC035055-1|AAH35055.1| 554|Homo sapiens gamma-aminobutyric acid... 46 1e-04
D49394-1|BAA08387.1| 478|Homo sapiens serotonin 5-HT3 receptor ... 46 2e-04
BT007204-1|AAP35868.1| 484|Homo sapiens 5-hydroxytryptamine (se... 46 2e-04
BC004453-1|AAH04453.2| 478|Homo sapiens 5-hydroxytryptamine (se... 46 2e-04
BC002354-1|AAH02354.1| 478|Homo sapiens 5-hydroxytryptamine (se... 46 2e-04
AJ005205-1|CAA06442.3| 478|Homo sapiens serotonin 3 receptor pr... 46 2e-04
AJ003079-1|CAA05852.1| 478|Homo sapiens 5-hydroxytryptamine3 re... 46 2e-04
AJ003078-1|CAA05851.1| 510|Homo sapiens serotonin receptor prot... 46 2e-04
AF498984-1|AAM21131.1| 478|Homo sapiens 5-hydroxytryptamine rec... 46 2e-04
BC096083-1|AAH96083.1| 198|Homo sapiens CHRNB4 protein protein. 45 4e-04
BC096081-1|AAH96081.1| 198|Homo sapiens CHRNB4 protein protein. 45 4e-04
BC033801-1|AAH33801.1| 452|Homo sapiens gamma-aminobutyric acid... 44 0.001
AL391845-4|CAI15436.1| 452|Homo sapiens gamma-aminobutyric acid... 44 0.001
AF016917-1|AAB70007.1| 452|Homo sapiens GABA-A receptor delta s... 44 0.001
U95367-1|AAC51357.1| 440|Homo sapiens GABA-A receptor pi subuni... 43 0.001
BC109211-1|AAI09212.1| 632|Homo sapiens gamma-aminobutyric acid... 43 0.001
BC109210-1|AAI09211.1| 632|Homo sapiens gamma-aminobutyric acid... 43 0.001
BC109106-1|AAI09107.1| 440|Homo sapiens gamma-aminobutyric acid... 43 0.001
BC109105-1|AAI09106.1| 440|Homo sapiens gamma-aminobutyric acid... 43 0.001
BC074865-1|AAH74865.1| 440|Homo sapiens gamma-aminobutyric acid... 43 0.001
BC074810-1|AAH74810.1| 440|Homo sapiens gamma-aminobutyric acid... 43 0.001
AF189259-1|AAF70380.1| 632|Homo sapiens GABA-A receptor theta s... 43 0.001
AF144648-1|AAD51172.1| 627|Homo sapiens GABA-A receptor theta p... 43 0.001
AF009702-1|AAC24194.1| 440|Homo sapiens GABA-A receptor pi subu... 43 0.001
X52009-1|CAA36258.1| 449|Homo sapiens inhibitory glycine recept... 43 0.002
BC114947-1|AAI14948.1| 457|Homo sapiens GLRA1 protein protein. 43 0.002
BC074980-1|AAH74980.1| 449|Homo sapiens glycine receptor, alpha... 43 0.002
BC031087-1|AAH31087.1| 465|Homo sapiens gamma-aminobutyric acid... 43 0.002
BC074795-1|AAH74795.1| 467|Homo sapiens gamma-aminobutyric acid... 42 0.004
BC069348-1|AAH69348.1| 467|Homo sapiens gamma-aminobutyric acid... 42 0.004
BC059389-1|AAH59389.1| 475|Homo sapiens gamma-aminobutyric acid... 42 0.004
AF165124-1|AAD50273.1| 467|Homo sapiens gamma-aminobutyric acid... 42 0.004
Z93848-1|CAI41994.1| 376|Homo sapiens glycine receptor, alpha 4... 41 0.007
U93917-1|AAC39917.1| 449|Homo sapiens glycine receptor alpha 3 ... 41 0.007
BC036086-1|AAH36086.1| 464|Homo sapiens glycine receptor, alpha... 41 0.007
AL049610-1|CAI42158.1| 376|Homo sapiens glycine receptor, alpha... 41 0.007
AF017724-1|AAC39919.1| 465|Homo sapiens glycine receptor alpha ... 41 0.007
X15376-1|CAA33437.1| 467|Homo sapiens GABA-A receptor gamma 2 s... 40 0.009
BC114967-1|AAI14968.1| 366|Homo sapiens GLRA1 protein protein. 40 0.009
AB209359-1|BAD92596.1| 533|Homo sapiens cholinergic receptor, n... 36 0.25
BC096291-1|AAH96291.1| 556|Homo sapiens CHRNA4 protein protein. 35 0.44
S80905-1|AAB50686.1| 382|Homo sapiens Con1 protein. 33 1.0
K03208-1|AAA60189.1| 251|Homo sapiens PRB2 protein. 33 1.0
K02575-1|AAA36502.1| 173|Homo sapiens protein ( Human salivary ... 33 1.0
S62941-1|AAB27289.1| 358|Homo sapiens Ps 2 protein. 32 3.1
BC146774-1|AAI46775.1| 1114|Homo sapiens GPR124 protein protein. 32 3.1
AY181242-1|AAO27354.1| 1331|Homo sapiens G protein-coupled recep... 32 3.1
AK074099-1|BAB84925.1| 1310|Homo sapiens FLJ00170 protein protein. 32 3.1
AF378755-1|AAL11992.1| 1331|Homo sapiens tumor endothelial marke... 32 3.1
AB040964-1|BAA96055.2| 1206|Homo sapiens KIAA1531 protein protein. 32 3.1
U83981-1|AAC25631.1| 674|Homo sapiens apoptosis associated prot... 31 5.4
CR457259-1|CAG33540.1| 674|Homo sapiens PPP1R15A protein. 31 5.4
BC003067-1|AAH03067.1| 674|Homo sapiens protein phosphatase 1, ... 31 5.4
AK001361-1|BAA91649.1| 674|Homo sapiens protein ( Homo sapiens ... 31 5.4
K03206-1|AAA60187.1| 178|Homo sapiens PRB1 protein. 30 9.5
K03205-1|AAA60186.1| 198|Homo sapiens PRB1 protein. 30 9.5
BC141917-1|AAI41918.1| 198|Homo sapiens PRB1 protein protein. 30 9.5
AK122582-1|BAC56923.1| 1383|Homo sapiens FLJ00269 protein protein. 30 9.5
>AJ306454-1|CAC34819.1| 497|Homo sapiens neuronal nicotinic
acetylcholine receptor beta-4 subunit protein.
Length = 497
Score = 68.9 bits (161), Expect = 2e-11
Identities = 45/168 (26%), Positives = 77/168 (45%), Gaps = 8/168 (4%)
Frame = +2
Query: 92 AIASAAECENATSLSLMIDSLL--ATYD---RDSPPDSKIV-VNLTLHLRHA-NIRESES 250
A+ C A + ++D LL Y+ R + S+++ + L L L ++ E E
Sbjct: 14 ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQ 73
Query: 251 TVRIQADLQMNWIGKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRAR 427
+ L+ W RL+WN+ + G + + ++R+W PD+VL N T
Sbjct: 74 IMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNDGTYEVSVYTNLI 133
Query: 428 VSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXSDEMD 571
V +NGSV W+ + +++ +P D Q CT KF S + E+D
Sbjct: 134 VRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRSWTYDHTEID 181
>Y08416-1|CAA69693.1| 498|Homo sapiens nicotinic acetylcholine
receptor beta4 subunit precursor protein.
Length = 498
Score = 66.9 bits (156), Expect = 9e-11
Identities = 46/169 (27%), Positives = 78/169 (46%), Gaps = 9/169 (5%)
Frame = +2
Query: 92 AIASAAECENATSLSLMIDSLL--ATYD---RDSPPDSKIV-VNLTLHLRHA-NIRESES 250
A+ C A + ++D LL Y+ R + S+++ + L L L ++ E E
Sbjct: 14 ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQ 73
Query: 251 TVRIQADLQMNWIGKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRA 424
+ L+ W RL+WN+ + G + + ++R+W PD+VL N A T
Sbjct: 74 IMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNADGTYEVSVYTNL 133
Query: 425 RVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXSDEMD 571
V +NGSV W+ + +++ +P D Q CT KF S + E+D
Sbjct: 134 IVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRSWTYDHTEID 182
>U62439-1|AAB40117.1| 498|Homo sapiens nicotinic acetylcholine
receptor beta4 subunit precursor protein.
Length = 498
Score = 66.9 bits (156), Expect = 9e-11
Identities = 46/169 (27%), Positives = 78/169 (46%), Gaps = 9/169 (5%)
Frame = +2
Query: 92 AIASAAECENATSLSLMIDSLL--ATYD---RDSPPDSKIV-VNLTLHLRHA-NIRESES 250
A+ C A + ++D LL Y+ R + S+++ + L L L ++ E E
Sbjct: 14 ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQ 73
Query: 251 TVRIQADLQMNWIGKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRA 424
+ L+ W RL+WN+ + G + + ++R+W PD+VL N A T
Sbjct: 74 IMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNADGTYEVSVYTNL 133
Query: 425 RVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXSDEMD 571
V +NGSV W+ + +++ +P D Q CT KF S + E+D
Sbjct: 134 IVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRSWTYDHTEID 182
>U48861-1|AAA92123.1| 498|Homo sapiens beta 4 nicotinic
acetylcholine receptor subunit protein.
Length = 498
Score = 66.9 bits (156), Expect = 9e-11
Identities = 46/169 (27%), Positives = 78/169 (46%), Gaps = 9/169 (5%)
Frame = +2
Query: 92 AIASAAECENATSLSLMIDSLL--ATYD---RDSPPDSKIV-VNLTLHLRHA-NIRESES 250
A+ C A + ++D LL Y+ R + S+++ + L L L ++ E E
Sbjct: 14 ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQ 73
Query: 251 TVRIQADLQMNWIGKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRA 424
+ L+ W RL+WN+ + G + + ++R+W PD+VL N A T
Sbjct: 74 IMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNADGTYEVSVYTNL 133
Query: 425 RVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXSDEMD 571
V +NGSV W+ + +++ +P D Q CT KF S + E+D
Sbjct: 134 IVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRSWTYDHTEID 182
>BC096082-1|AAH96082.1| 498|Homo sapiens cholinergic receptor,
nicotinic, beta 4 protein.
Length = 498
Score = 66.9 bits (156), Expect = 9e-11
Identities = 46/169 (27%), Positives = 78/169 (46%), Gaps = 9/169 (5%)
Frame = +2
Query: 92 AIASAAECENATSLSLMIDSLL--ATYD---RDSPPDSKIV-VNLTLHLRHA-NIRESES 250
A+ C A + ++D LL Y+ R + S+++ + L L L ++ E E
Sbjct: 14 ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQ 73
Query: 251 TVRIQADLQMNWIGKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRA 424
+ L+ W RL+WN+ + G + + ++R+W PD+VL N A T
Sbjct: 74 IMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNADGTYEVSVYTNL 133
Query: 425 RVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXSDEMD 571
V +NGSV W+ + +++ +P D Q CT KF S + E+D
Sbjct: 134 IVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRSWTYDHTEID 182
>BC096080-1|AAH96080.1| 498|Homo sapiens cholinergic receptor,
nicotinic, beta 4 protein.
Length = 498
Score = 66.9 bits (156), Expect = 9e-11
Identities = 46/169 (27%), Positives = 78/169 (46%), Gaps = 9/169 (5%)
Frame = +2
Query: 92 AIASAAECENATSLSLMIDSLL--ATYD---RDSPPDSKIV-VNLTLHLRHA-NIRESES 250
A+ C A + ++D LL Y+ R + S+++ + L L L ++ E E
Sbjct: 14 ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQ 73
Query: 251 TVRIQADLQMNWIGKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRA 424
+ L+ W RL+WN+ + G + + ++R+W PD+VL N A T
Sbjct: 74 IMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNADGTYEVSVYTNL 133
Query: 425 RVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXSDEMD 571
V +NGSV W+ + +++ +P D Q CT KF S + E+D
Sbjct: 134 IVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRSWTYDHTEID 182
>AF306329-1|AAL02062.1| 498|Homo sapiens neuronal nicotinic
acetylcholine receptor beta 4 subunit protein.
Length = 498
Score = 66.9 bits (156), Expect = 9e-11
Identities = 46/169 (27%), Positives = 78/169 (46%), Gaps = 9/169 (5%)
Frame = +2
Query: 92 AIASAAECENATSLSLMIDSLL--ATYD---RDSPPDSKIV-VNLTLHLRHA-NIRESES 250
A+ C A + ++D LL Y+ R + S+++ + L L L ++ E E
Sbjct: 14 ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQ 73
Query: 251 TVRIQADLQMNWIGKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRA 424
+ L+ W RL+WN+ + G + + ++R+W PD+VL N A T
Sbjct: 74 IMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNADGTYEVSVYTNL 133
Query: 425 RVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXSDEMD 571
V +NGSV W+ + +++ +P D Q CT KF S + E+D
Sbjct: 134 IVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRSWTYDHTEID 182
>X68275-1|CAA48336.1| 451|Homo sapiens nicotinic receptor beta 4
subunit protein.
Length = 451
Score = 62.9 bits (146), Expect = 1e-09
Identities = 37/129 (28%), Positives = 61/129 (47%), Gaps = 3/129 (2%)
Frame = +2
Query: 194 IVVNLTLHLRHA-NIRESESTVRIQADLQMNWIGKRLSWNAGEW-GCSTWLVSSERLWRP 367
I + L L L ++ E + + L+ W RL+WN+ + G + + ++R+W P
Sbjct: 7 ISIKLQLSLAQLISVNERDEIMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLP 66
Query: 368 DVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 544
D+VL N A T V +NGSV W+ + +++ +P D Q CT KF S
Sbjct: 67 DIVLYNNADGTYEVSVYTNLIVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRS 126
Query: 545 RMHXSDEMD 571
+ E+D
Sbjct: 127 WTYDHTEID 135
>Y08417-1|CAA69694.1| 458|Homo sapiens nicotinic acetylcholine
receptor beta3 subunit precursor protein.
Length = 458
Score = 62.1 bits (144), Expect = 3e-09
Identities = 34/116 (29%), Positives = 53/116 (45%), Gaps = 2/116 (1%)
Frame = +2
Query: 230 NIRESESTVRIQADLQMNWIGKRLSWNAGEWG-CSTWLVSSERLWRPDVVLL-NAAATTA 403
++ E + L+ W +L WN ++G + V SE LW PD+VL NA
Sbjct: 67 DVDEKNQLMTTNVWLKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFE 126
Query: 404 GDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXSDEMD 571
G + V +NG+V W + +M + +P D Q C+ KFGS + +D
Sbjct: 127 GSLMTKVIVKSNGTVVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGTMVD 182
>X67513-1|CAA47851.1| 423|Homo sapiens nicotinic acetylcholine
receptor beta-3 subunit protein.
Length = 423
Score = 62.1 bits (144), Expect = 3e-09
Identities = 34/116 (29%), Positives = 53/116 (45%), Gaps = 2/116 (1%)
Frame = +2
Query: 230 NIRESESTVRIQADLQMNWIGKRLSWNAGEWG-CSTWLVSSERLWRPDVVLL-NAAATTA 403
++ E + L+ W +L WN ++G + V SE LW PD+VL NA
Sbjct: 32 DVDEKNQLMTTNVWLKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFE 91
Query: 404 GDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXSDEMD 571
G + V +NG+V W + +M + +P D Q C+ KFGS + +D
Sbjct: 92 GSLMTKVIVKSNGTVVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGTMVD 147
>U62438-1|AAB40116.1| 458|Homo sapiens nicotinic acetylcholine
receptor beta3 subunit precursor protein.
Length = 458
Score = 62.1 bits (144), Expect = 3e-09
Identities = 34/116 (29%), Positives = 53/116 (45%), Gaps = 2/116 (1%)
Frame = +2
Query: 230 NIRESESTVRIQADLQMNWIGKRLSWNAGEWG-CSTWLVSSERLWRPDVVLL-NAAATTA 403
++ E + L+ W +L WN ++G + V SE LW PD+VL NA
Sbjct: 67 DVDEKNQLMTTNVWLKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFE 126
Query: 404 GDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXSDEMD 571
G + V +NG+V W + +M + +P D Q C+ KFGS + +D
Sbjct: 127 GSLMTKVIVKSNGTVVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGTMVD 182
>BC069788-1|AAH69788.1| 458|Homo sapiens cholinergic receptor,
nicotinic, beta 3 protein.
Length = 458
Score = 62.1 bits (144), Expect = 3e-09
Identities = 34/116 (29%), Positives = 53/116 (45%), Gaps = 2/116 (1%)
Frame = +2
Query: 230 NIRESESTVRIQADLQMNWIGKRLSWNAGEWG-CSTWLVSSERLWRPDVVLL-NAAATTA 403
++ E + L+ W +L WN ++G + V SE LW PD+VL NA
Sbjct: 67 DVDEKNQLMTTNVWLKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFE 126
Query: 404 GDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXSDEMD 571
G + V +NG+V W + +M + +P D Q C+ KFGS + +D
Sbjct: 127 GSLMTKVIVKSNGTVVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGTMVD 182
>BC069703-1|AAH69703.1| 458|Homo sapiens cholinergic receptor,
nicotinic, beta 3 protein.
Length = 458
Score = 62.1 bits (144), Expect = 3e-09
Identities = 34/116 (29%), Positives = 53/116 (45%), Gaps = 2/116 (1%)
Frame = +2
Query: 230 NIRESESTVRIQADLQMNWIGKRLSWNAGEWG-CSTWLVSSERLWRPDVVLL-NAAATTA 403
++ E + L+ W +L WN ++G + V SE LW PD+VL NA
Sbjct: 67 DVDEKNQLMTTNVWLKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFE 126
Query: 404 GDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXSDEMD 571
G + V +NG+V W + +M + +P D Q C+ KFGS + +D
Sbjct: 127 GSLMTKVIVKSNGTVVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGTMVD 182
>BC069681-1|AAH69681.1| 458|Homo sapiens cholinergic receptor,
nicotinic, beta 3 protein.
Length = 458
Score = 62.1 bits (144), Expect = 3e-09
Identities = 34/116 (29%), Positives = 53/116 (45%), Gaps = 2/116 (1%)
Frame = +2
Query: 230 NIRESESTVRIQADLQMNWIGKRLSWNAGEWG-CSTWLVSSERLWRPDVVLL-NAAATTA 403
++ E + L+ W +L WN ++G + V SE LW PD+VL NA
Sbjct: 67 DVDEKNQLMTTNVWLKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFE 126
Query: 404 GDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXSDEMD 571
G + V +NG+V W + +M + +P D Q C+ KFGS + +D
Sbjct: 127 GSLMTKVIVKSNGTVVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGTMVD 182
>AF140765-1|AAD33063.1| 458|Homo sapiens neuronal acetylcholine
receptor beta-3 subunit precursor protein.
Length = 458
Score = 62.1 bits (144), Expect = 3e-09
Identities = 34/116 (29%), Positives = 53/116 (45%), Gaps = 2/116 (1%)
Frame = +2
Query: 230 NIRESESTVRIQADLQMNWIGKRLSWNAGEWG-CSTWLVSSERLWRPDVVLL-NAAATTA 403
++ E + L+ W +L WN ++G + V SE LW PD+VL NA
Sbjct: 67 DVDEKNQLMTTNVWLKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFE 126
Query: 404 GDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXSDEMD 571
G + V +NG+V W + +M + +P D Q C+ KFGS + +D
Sbjct: 127 GSLMTKVIVKSNGTVVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGTMVD 182
>Y16281-1|CAA76154.1| 529|Homo sapiens nicotinic acetylcholine
receptor alpha2 subunit precursor protein.
Length = 529
Score = 61.7 bits (143), Expect = 3e-09
Identities = 34/124 (27%), Positives = 59/124 (47%), Gaps = 2/124 (1%)
Frame = +2
Query: 230 NIRESESTVRIQADLQMNWIGKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAA-ATTA 403
++ E + L+ W +L WN ++G T L V SE +W PD+VL N A A
Sbjct: 97 DVDEKNQMMTTNVWLKQEWSDYKLRWNPADFGNITSLRVPSEMIWIPDIVLYNNADGEFA 156
Query: 404 GDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXSDEMDFRD* 583
+ +A + + G+V W+ + S+ + +P D Q C KFGS + ++D
Sbjct: 157 VTHMTKAHLFSTGTVHWVPPAIYKSSCSIDVTFFPFDQQNCKMKFGSWTYDKAKIDLEQM 216
Query: 584 QKNI 595
++ +
Sbjct: 217 EQTV 220
>Y08419-1|CAA69696.1| 468|Homo sapiens nicotinic acetylcholine
receptor alpha5 subunit precursor protein.
Length = 468
Score = 61.7 bits (143), Expect = 3e-09
Identities = 36/150 (24%), Positives = 69/150 (46%), Gaps = 6/150 (4%)
Frame = +2
Query: 140 MIDSLLATYDRDSPP----DSKIVVNLTLHLRH-ANIRESESTVRIQADLQMNWIGKRLS 304
++ L Y+R P + KI + L + ++ E + L+ WI +L
Sbjct: 50 LLKDLFQDYERWVRPVEHLNDKIKIKFGLAISQLVDVDEKNQLMTTNVWLKQEWIDVKLR 109
Query: 305 WNAGEWG-CSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVSWIKRLDISTP 481
WN ++G V S+ +W PD+VL + A + + + NG+V+W + +
Sbjct: 110 WNPDDYGGIKVIRVPSDSVWTPDIVLFDNADGRFEGTSTKTVIRYNGTVTWTPPANYKSS 169
Query: 482 ISMQLDNWPNDMQTCTFKFGSRMHXSDEMD 571
++ + +P D+Q C+ KFGS + ++D
Sbjct: 170 CTIDVTFFPFDLQNCSMKFGSWTYDGSQVD 199
>U62434-1|AAB40112.1| 468|Homo sapiens nicotinic acetylcholine
receptor alpha5 subunit precursor protein.
Length = 468
Score = 61.7 bits (143), Expect = 3e-09
Identities = 36/150 (24%), Positives = 69/150 (46%), Gaps = 6/150 (4%)
Frame = +2
Query: 140 MIDSLLATYDRDSPP----DSKIVVNLTLHLRH-ANIRESESTVRIQADLQMNWIGKRLS 304
++ L Y+R P + KI + L + ++ E + L+ WI +L
Sbjct: 50 LLKDLFQDYERWVRPVEHLNDKIKIKFGLAISQLVDVDEKNQLMTTNVWLKQEWIDVKLR 109
Query: 305 WNAGEWG-CSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVSWIKRLDISTP 481
WN ++G V S+ +W PD+VL + A + + + NG+V+W + +
Sbjct: 110 WNPDDYGGIKVIRVPSDSVWTPDIVLFDNADGRFEGTSTKTVIRYNGTVTWTPPANYKSS 169
Query: 482 ISMQLDNWPNDMQTCTFKFGSRMHXSDEMD 571
++ + +P D+Q C+ KFGS + ++D
Sbjct: 170 CTIDVTFFPFDLQNCSMKFGSWTYDGSQVD 199
>U62431-1|AAB40109.1| 529|Homo sapiens nicotinic acetylcholine
receptor alpha2 subunit precursor protein.
Length = 529
Score = 61.7 bits (143), Expect = 3e-09
Identities = 34/124 (27%), Positives = 59/124 (47%), Gaps = 2/124 (1%)
Frame = +2
Query: 230 NIRESESTVRIQADLQMNWIGKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAA-ATTA 403
++ E + L+ W +L WN ++G T L V SE +W PD+VL N A A
Sbjct: 97 DVDEKNQMMTTNVWLKQEWSDYKLRWNPADFGNITSLRVPSEMIWIPDIVLYNNADGEFA 156
Query: 404 GDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXSDEMDFRD* 583
+ +A + + G+V W+ + S+ + +P D Q C KFGS + ++D
Sbjct: 157 VTHMTKAHLFSTGTVHWVPPAIYKSSCSIDVTFFPFDQQNCKMKFGSWTYDKAKIDLEQM 216
Query: 584 QKNI 595
++ +
Sbjct: 217 EQTV 220
>BC033639-1|AAH33639.1| 468|Homo sapiens cholinergic receptor,
nicotinic, alpha 5 protein.
Length = 468
Score = 61.7 bits (143), Expect = 3e-09
Identities = 36/150 (24%), Positives = 69/150 (46%), Gaps = 6/150 (4%)
Frame = +2
Query: 140 MIDSLLATYDRDSPP----DSKIVVNLTLHLRH-ANIRESESTVRIQADLQMNWIGKRLS 304
++ L Y+R P + KI + L + ++ E + L+ WI +L
Sbjct: 50 LLKDLFQDYERWVRPVEHLNDKIKIKFGLAISQLVDVDEKNQLMTTNVWLKQEWIDVKLR 109
Query: 305 WNAGEWG-CSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVSWIKRLDISTP 481
WN ++G V S+ +W PD+VL + A + + + NG+V+W + +
Sbjct: 110 WNPDDYGGIKVIRVPSDSVWTPDIVLFDNADGRFEGTSTKTVIRYNGTVTWTPPANYKSS 169
Query: 482 ISMQLDNWPNDMQTCTFKFGSRMHXSDEMD 571
++ + +P D+Q C+ KFGS + ++D
Sbjct: 170 CTIDVTFFPFDLQNCSMKFGSWTYDGSQVD 199
>AJ306481-1|CAC34820.1| 468|Homo sapiens neuronal nicotinic
acetylcholine receptor alpha-5subunit protein.
Length = 468
Score = 61.7 bits (143), Expect = 3e-09
Identities = 36/150 (24%), Positives = 69/150 (46%), Gaps = 6/150 (4%)
Frame = +2
Query: 140 MIDSLLATYDRDSPP----DSKIVVNLTLHLRH-ANIRESESTVRIQADLQMNWIGKRLS 304
++ L Y+R P + KI + L + ++ E + L+ WI +L
Sbjct: 50 LLKDLFQDYERWVRPVEHLNDKIKIKFGLAISQLVDVDEKNQLMTTNVWLKQEWIDVKLR 109
Query: 305 WNAGEWG-CSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVSWIKRLDISTP 481
WN ++G V S+ +W PD+VL + A + + + NG+V+W + +
Sbjct: 110 WNPDDYGGIKVIRVPSDSVWTPDIVLFDNADGRFEGTSTKTVIRYNGTVTWTPPANYKSS 169
Query: 482 ISMQLDNWPNDMQTCTFKFGSRMHXSDEMD 571
++ + +P D+Q C+ KFGS + ++D
Sbjct: 170 CTIDVTFFPFDLQNCSMKFGSWTYDGSQVD 199
>Y16282-1|CAA76155.1| 494|Homo sapiens nicotinic acetylcholine
receptor alpha6 subunit precursor protein.
Length = 494
Score = 61.3 bits (142), Expect = 4e-09
Identities = 41/163 (25%), Positives = 74/163 (45%), Gaps = 10/163 (6%)
Frame = +2
Query: 113 CENATSLSLMIDSLLATYDRDSPPDSKIVVNLTLHL-----RHANIRESESTVRIQADLQ 277
C + + L + Y++ P + +T+H + AN+ E + L+
Sbjct: 28 CVGCATEERLFHKLFSHYNQFIRPVENVSDPVTVHFEVAITQLANVDEVNQIMETNLWLR 87
Query: 278 MNWIGKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNG 442
W +L W+ E+ G T V ++++W+PD+VL N A GD+ + +A + NG
Sbjct: 88 HIWNDYKLRWDPMEYDGIETLRVPADKIWKPDIVLYNNAV---GDFQVEGKTKALLKYNG 144
Query: 443 SVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXSDEMD 571
++W + M + +P D Q C+ KFGS + E+D
Sbjct: 145 MITWTPPAIFKSSCPMDITFFPFDHQNCSLKFGSWTYDKAEID 187
>X14830-1|CAA32939.1| 501|Homo sapiens protein ( Human mRNA for
muscle acetylcholine receptor beta-subunit. ).
Length = 501
Score = 61.3 bits (142), Expect = 4e-09
Identities = 44/133 (33%), Positives = 67/133 (50%), Gaps = 4/133 (3%)
Frame = +2
Query: 191 KIVVNLTL-HLRHANIRESESTVRIQADLQMNWIGKRLSWNAGEW-GCSTWLVSSERLWR 364
++ V L L L N ++ E + ++ DL+ W RLSW+ E G + +++E +W
Sbjct: 53 RVSVGLILAQLISLNEKDEEMSTKVYLDLE--WTDYRLSWDPAEHDGIDSLRITAESVWL 110
Query: 365 PDVVLLNAAATTAGDYAL--RARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKF 538
PDVVLLN D AL VS++GSV W + S+Q+ +P D Q CT F
Sbjct: 111 PDVVLLNNNDGNF-DVALDISVVVSSDGSVRWQPPGIYRSSCSIQVTYFPFDWQNCTMVF 169
Query: 539 GSRMHXSDEMDFR 577
S + S E+ +
Sbjct: 170 SSYSYDSSEVSLQ 182
>U62435-1|AAB40113.1| 494|Homo sapiens nicotinic acetylcholine
receptor alpha6 subunit precursor protein.
Length = 494
Score = 61.3 bits (142), Expect = 4e-09
Identities = 41/163 (25%), Positives = 74/163 (45%), Gaps = 10/163 (6%)
Frame = +2
Query: 113 CENATSLSLMIDSLLATYDRDSPPDSKIVVNLTLHL-----RHANIRESESTVRIQADLQ 277
C + + L + Y++ P + +T+H + AN+ E + L+
Sbjct: 28 CVGCATEERLFHKLFSHYNQFIRPVENVSDPVTVHFEVAITQLANVDEVNQIMETNLWLR 87
Query: 278 MNWIGKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNG 442
W +L W+ E+ G T V ++++W+PD+VL N A GD+ + +A + NG
Sbjct: 88 HIWNDYKLRWDPMEYDGIETLRVPADKIWKPDIVLYNNAV---GDFQVEGKTKALLKYNG 144
Query: 443 SVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXSDEMD 571
++W + M + +P D Q C+ KFGS + E+D
Sbjct: 145 MITWTPPAIFKSSCPMDITFFPFDHQNCSLKFGSWTYDKAEID 187
>BC014456-1|AAH14456.1| 494|Homo sapiens cholinergic receptor,
nicotinic, alpha 6 protein.
Length = 494
Score = 61.3 bits (142), Expect = 4e-09
Identities = 41/163 (25%), Positives = 74/163 (45%), Gaps = 10/163 (6%)
Frame = +2
Query: 113 CENATSLSLMIDSLLATYDRDSPPDSKIVVNLTLHL-----RHANIRESESTVRIQADLQ 277
C + + L + Y++ P + +T+H + AN+ E + L+
Sbjct: 28 CVGCATEERLFHKLFSHYNQFIRPVENVSDPVTVHFEVAITQLANVDEVNQIMETNLWLR 87
Query: 278 MNWIGKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNG 442
W +L W+ E+ G T V ++++W+PD+VL N A GD+ + +A + NG
Sbjct: 88 HIWNDYKLRWDPMEYDGIETLRVPADKIWKPDIVLYNNAV---GDFQVEGKTKALLKYNG 144
Query: 443 SVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXSDEMD 571
++W + M + +P D Q C+ KFGS + E+D
Sbjct: 145 MITWTPPAIFKSSCPMDITFFPFDHQNCSLKFGSWTYDKAEID 187
>BC011371-1|AAH11371.1| 501|Homo sapiens cholinergic receptor,
nicotinic, beta 1 (muscle) protein.
Length = 501
Score = 61.3 bits (142), Expect = 4e-09
Identities = 44/133 (33%), Positives = 67/133 (50%), Gaps = 4/133 (3%)
Frame = +2
Query: 191 KIVVNLTL-HLRHANIRESESTVRIQADLQMNWIGKRLSWNAGEW-GCSTWLVSSERLWR 364
++ V L L L N ++ E + ++ DL+ W RLSW+ E G + +++E +W
Sbjct: 53 RVSVGLILAQLISLNEKDEEMSTKVYLDLE--WTDYRLSWDPAEHDGIDSLRITAESVWL 110
Query: 365 PDVVLLNAAATTAGDYAL--RARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKF 538
PDVVLLN D AL VS++GSV W + S+Q+ +P D Q CT F
Sbjct: 111 PDVVLLNNNDGNF-DVALDISVVVSSDGSVRWQPPGIYRSSCSIQVTYFPFDWQNCTMVF 169
Query: 539 GSRMHXSDEMDFR 577
S + S E+ +
Sbjct: 170 SSYSYDSSEVSLQ 182
>AB079251-1|BAC06855.1| 494|Homo sapiens Nicotinic acetylcholine
receptor alpha 6 protein.
Length = 494
Score = 61.3 bits (142), Expect = 4e-09
Identities = 41/163 (25%), Positives = 74/163 (45%), Gaps = 10/163 (6%)
Frame = +2
Query: 113 CENATSLSLMIDSLLATYDRDSPPDSKIVVNLTLHL-----RHANIRESESTVRIQADLQ 277
C + + L + Y++ P + +T+H + AN+ E + L+
Sbjct: 28 CVGCATEERLFHKLFSHYNQFIRPVENVSDPVTVHFEVAITQLANVDEVNQIMETNLWLR 87
Query: 278 MNWIGKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNG 442
W +L W+ E+ G T V ++++W+PD+VL N A GD+ + +A + NG
Sbjct: 88 HIWNDYKLRWDPMEYDGIETLRVPADKIWKPDIVLYNNAV---GDFQVEGKTKALLKYNG 144
Query: 443 SVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXSDEMD 571
++W + M + +P D Q C+ KFGS + E+D
Sbjct: 145 MITWTPPAIFKSSCPMDITFFPFDHQNCSLKFGSWTYDKAEID 187
>Y08418-1|CAA69695.1| 503|Homo sapiens nicotinic acetylcholine
receptor alpha3 subunit precursor protein.
Length = 503
Score = 60.5 bits (140), Expect = 8e-09
Identities = 30/102 (29%), Positives = 53/102 (51%), Gaps = 2/102 (1%)
Frame = +2
Query: 272 LQMNWIGKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 445
L+ W +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 85 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 144
Query: 446 VSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXSDEMD 571
V+WI + + + +P D Q CT KFGS + ++D
Sbjct: 145 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKID 186
>X53559-1|CAA37625.1| 474|Homo sapiens neuronal nicotinic
acetylcholine receptor alpha-3merase protein.
Length = 474
Score = 60.5 bits (140), Expect = 8e-09
Identities = 30/102 (29%), Positives = 53/102 (51%), Gaps = 2/102 (1%)
Frame = +2
Query: 272 LQMNWIGKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 445
L+ W +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 56 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 115
Query: 446 VSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXSDEMD 571
V+WI + + + +P D Q CT KFGS + ++D
Sbjct: 116 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKID 157
>U62432-1|AAB40110.1| 504|Homo sapiens nicotinic acetylcholine
receptor alpha3 subunit precursor protein.
Length = 504
Score = 60.5 bits (140), Expect = 8e-09
Identities = 30/102 (29%), Positives = 53/102 (51%), Gaps = 2/102 (1%)
Frame = +2
Query: 272 LQMNWIGKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 445
L+ W +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 86 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 145
Query: 446 VSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXSDEMD 571
V+WI + + + +P D Q CT KFGS + ++D
Sbjct: 146 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKID 187
>M83712-1|AAA58357.1| 468|Homo sapiens nicotinic receptor alpha 5
subunit protein.
Length = 468
Score = 60.5 bits (140), Expect = 8e-09
Identities = 36/150 (24%), Positives = 68/150 (45%), Gaps = 6/150 (4%)
Frame = +2
Query: 140 MIDSLLATYDRDSPP----DSKIVVNLTLHLRH-ANIRESESTVRIQADLQMNWIGKRLS 304
++ L Y+R P + KI + L + ++ E + L+ WI +L
Sbjct: 50 LLKDLFQDYERWVRPVEHLNDKIKIKFGLAISQLVDVDEKNQLMTTNVWLKQEWIDVKLR 109
Query: 305 WNAGEWG-CSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVSWIKRLDISTP 481
WN ++G V S+ W PD+VL + A + + + NG+V+W + +
Sbjct: 110 WNPDDYGGIKVIRVPSDSSWTPDIVLFDNADGRFEGTSTKTVIRYNGTVTWTPPANYKSS 169
Query: 482 ISMQLDNWPNDMQTCTFKFGSRMHXSDEMD 571
++ + +P D+Q C+ KFGS + ++D
Sbjct: 170 CTIDVTFFPFDLQNCSMKFGSWTYDGSQVD 199
>M37981-1|AAA59942.1| 503|Homo sapiens neuronal nicotinic
acetylcholine receptor protein.
Length = 503
Score = 60.5 bits (140), Expect = 8e-09
Identities = 30/102 (29%), Positives = 53/102 (51%), Gaps = 2/102 (1%)
Frame = +2
Query: 272 LQMNWIGKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 445
L+ W +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 85 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 144
Query: 446 VSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXSDEMD 571
V+WI + + + +P D Q CT KFGS + ++D
Sbjct: 145 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKID 186
>BT006897-1|AAP35543.1| 505|Homo sapiens cholinergic receptor,
nicotinic, alpha polypeptide 3 protein.
Length = 505
Score = 60.5 bits (140), Expect = 8e-09
Identities = 30/102 (29%), Positives = 53/102 (51%), Gaps = 2/102 (1%)
Frame = +2
Query: 272 LQMNWIGKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 445
L+ W +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 87 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 146
Query: 446 VSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXSDEMD 571
V+WI + + + +P D Q CT KFGS + ++D
Sbjct: 147 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKID 188
>BT006646-1|AAP35292.1| 489|Homo sapiens cholinergic receptor,
nicotinic, alpha polypeptide 3 protein.
Length = 489
Score = 60.5 bits (140), Expect = 8e-09
Identities = 30/102 (29%), Positives = 53/102 (51%), Gaps = 2/102 (1%)
Frame = +2
Query: 272 LQMNWIGKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 445
L+ W +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 87 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 146
Query: 446 VSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXSDEMD 571
V+WI + + + +P D Q CT KFGS + ++D
Sbjct: 147 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKID 188
>BC098443-1|AAH98443.1| 504|Homo sapiens cholinergic receptor,
nicotinic, alpha 3 protein.
Length = 504
Score = 60.5 bits (140), Expect = 8e-09
Identities = 30/102 (29%), Positives = 53/102 (51%), Gaps = 2/102 (1%)
Frame = +2
Query: 272 LQMNWIGKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 445
L+ W +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 86 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 145
Query: 446 VSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXSDEMD 571
V+WI + + + +P D Q CT KFGS + ++D
Sbjct: 146 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKID 187
>BC006114-1|AAH06114.1| 489|Homo sapiens CHRNA3 protein protein.
Length = 489
Score = 60.5 bits (140), Expect = 8e-09
Identities = 30/102 (29%), Positives = 53/102 (51%), Gaps = 2/102 (1%)
Frame = +2
Query: 272 LQMNWIGKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 445
L+ W +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 87 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 146
Query: 446 VSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXSDEMD 571
V+WI + + + +P D Q CT KFGS + ++D
Sbjct: 147 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKID 188
>BC002996-1|AAH02996.1| 505|Homo sapiens cholinergic receptor,
nicotinic, alpha 3 protein.
Length = 505
Score = 60.5 bits (140), Expect = 8e-09
Identities = 30/102 (29%), Positives = 53/102 (51%), Gaps = 2/102 (1%)
Frame = +2
Query: 272 LQMNWIGKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 445
L+ W +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 87 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 146
Query: 446 VSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXSDEMD 571
V+WI + + + +P D Q CT KFGS + ++D
Sbjct: 147 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKID 188
>BC001642-1|AAH01642.1| 505|Homo sapiens cholinergic receptor,
nicotinic, alpha 3 protein.
Length = 505
Score = 60.5 bits (140), Expect = 8e-09
Identities = 30/102 (29%), Positives = 53/102 (51%), Gaps = 2/102 (1%)
Frame = +2
Query: 272 LQMNWIGKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 445
L+ W +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 87 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 146
Query: 446 VSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXSDEMD 571
V+WI + + + +P D Q CT KFGS + ++D
Sbjct: 147 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKID 188
>BC000513-1|AAH00513.1| 505|Homo sapiens cholinergic receptor,
nicotinic, alpha 3 protein.
Length = 505
Score = 60.5 bits (140), Expect = 8e-09
Identities = 30/102 (29%), Positives = 53/102 (51%), Gaps = 2/102 (1%)
Frame = +2
Query: 272 LQMNWIGKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 445
L+ W +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 87 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 146
Query: 446 VSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXSDEMD 571
V+WI + + + +P D Q CT KFGS + ++D
Sbjct: 147 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKID 188
>AJ007783-1|CAA07682.1| 504|Homo sapiens nicotinic acetylcholine
receptor alpha-3 subunit protein.
Length = 504
Score = 60.5 bits (140), Expect = 8e-09
Identities = 30/102 (29%), Positives = 53/102 (51%), Gaps = 2/102 (1%)
Frame = +2
Query: 272 LQMNWIGKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 445
L+ W +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 86 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 145
Query: 446 VSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXSDEMD 571
V+WI + + + +P D Q CT KFGS + ++D
Sbjct: 146 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKID 187
>AF385584-1|AAK68110.1| 489|Homo sapiens nicotinic cholinergic
receptor alpha 3 protein.
Length = 489
Score = 60.5 bits (140), Expect = 8e-09
Identities = 30/102 (29%), Positives = 53/102 (51%), Gaps = 2/102 (1%)
Frame = +2
Query: 272 LQMNWIGKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 445
L+ W +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 81 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 140
Query: 446 VSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXSDEMD 571
V+WI + + + +P D Q CT KFGS + ++D
Sbjct: 141 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKID 182
>BC023553-1|AAH23553.1| 501|Homo sapiens cholinergic receptor,
nicotinic, beta 1 (muscle) protein.
Length = 501
Score = 60.1 bits (139), Expect = 1e-08
Identities = 42/135 (31%), Positives = 68/135 (50%), Gaps = 6/135 (4%)
Frame = +2
Query: 191 KIVVNLTL-HLRHANIRESESTVRIQADLQMNWIGKRLSWNAGEW-GCSTWLVSSERLWR 364
++ V L L L N ++ E + ++ DL+ W RLSW+ E G + +++E +W
Sbjct: 53 RVSVGLILAQLISLNEKDEEMSTKVYLDLE--WTDYRLSWDPAEHDGIDSLRITAESVWL 110
Query: 365 PDVVLLNAAATTAGDY----ALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTF 532
PDVVLLN G++ + VS++GSV W + S+Q+ +P D Q CT
Sbjct: 111 PDVVLLN---NNDGNFYVALDISVVVSSDGSVRWQPPGIYRSSCSIQVTYFPFDWQNCTM 167
Query: 533 KFGSRMHXSDEMDFR 577
F S + S E+ +
Sbjct: 168 VFSSYSYDSSEVSLQ 182
>X01715-1|CAA25861.1| 520|Homo sapiens acetylcholine receptor gamma
chain precursor protein.
Length = 520
Score = 58.8 bits (136), Expect = 2e-08
Identities = 42/154 (27%), Positives = 73/154 (47%), Gaps = 8/154 (5%)
Frame = +2
Query: 140 MIDSLLATYDRDSPPDSKI--VVNLTLHLRHANI---RESESTVRIQADLQMNWIGKRLS 304
++ L+ YD + P + VVN++L L N+ E E + ++M W RL
Sbjct: 32 LLADLMQNYDPNLRPAERDSDVVNVSLKLTLTNLISLNEREEALTTNVWIEMQWCDYRLR 91
Query: 305 WNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARV--SNNGSVSWIKRLDIS 475
W+ ++ G V S +WRPD+VL N + AL V S +G + W+
Sbjct: 92 WDPRDYEGLWVLRVPSTMVWRPDIVLENNVDGVF-EVALYCNVLVSPDGCIYWLPPAIFR 150
Query: 476 TPISMQLDNWPNDMQTCTFKFGSRMHXSDEMDFR 577
+ S+ + +P D Q C+ F S+ + ++E+D +
Sbjct: 151 SACSISVTYFPFDWQNCSLIFQSQTYSTNEIDLQ 184
>AC092165-3|AAY24103.1| 520|Homo sapiens unknown protein.
Length = 520
Score = 58.8 bits (136), Expect = 2e-08
Identities = 42/154 (27%), Positives = 73/154 (47%), Gaps = 8/154 (5%)
Frame = +2
Query: 140 MIDSLLATYDRDSPPDSKI--VVNLTLHLRHANI---RESESTVRIQADLQMNWIGKRLS 304
++ L+ YD + P + VVN++L L N+ E E + ++M W RL
Sbjct: 32 LLADLMQNYDPNLRPAERDSDVVNVSLKLTLTNLISLNEREEALTTNVWIEMQWCDYRLR 91
Query: 305 WNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARV--SNNGSVSWIKRLDIS 475
W+ ++ G V S +WRPD+VL N + AL V S +G + W+
Sbjct: 92 WDPRDYEGLWVLRVPSTMVWRPDIVLENNVDGVF-EVALYCNVLVSPDGCIYWLPPAIFR 150
Query: 476 TPISMQLDNWPNDMQTCTFKFGSRMHXSDEMDFR 577
+ S+ + +P D Q C+ F S+ + ++E+D +
Sbjct: 151 SACSISVTYFPFDWQNCSLIFQSQTYSTNEIDLQ 184
>X66403-1|CAA47030.1| 493|Homo sapiens acetylcholine receptor
epsilon subunit CHRNE protein.
Length = 493
Score = 58.4 bits (135), Expect = 3e-08
Identities = 34/134 (25%), Positives = 69/134 (51%), Gaps = 3/134 (2%)
Frame = +2
Query: 182 PDSKIVVNLTLHLRHA-NIRESESTVRIQADLQMNWIGKRLSWNAGEWG-CSTWLVSSER 355
P+ + ++L + L + ++ E E T+ + ++W RL+++ ++G T V SE
Sbjct: 45 PEDTVTISLKVTLTNLISLNEKEETLTTSVWIGIDWQDYRLNYSKDDFGGIETLRVPSEL 104
Query: 356 LWRPDVVLLNAAATTAG-DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTF 532
+W P++VL N G Y V GSV+W+ + ++++ +P D Q C+
Sbjct: 105 VWLPEIVLENNIDGQFGVAYDANVLVYEGGSVTWLPPAIYRSVCAVEVTYFPFDWQNCSL 164
Query: 533 KFGSRMHXSDEMDF 574
F S+ + ++E++F
Sbjct: 165 IFRSQTYNAEEVEF 178
>AF105999-1|AAD24503.1| 493|Homo sapiens acetylcholine receptor
epsilon subunit protein.
Length = 493
Score = 58.4 bits (135), Expect = 3e-08
Identities = 34/134 (25%), Positives = 69/134 (51%), Gaps = 3/134 (2%)
Frame = +2
Query: 182 PDSKIVVNLTLHLRHA-NIRESESTVRIQADLQMNWIGKRLSWNAGEWG-CSTWLVSSER 355
P+ + ++L + L + ++ E E T+ + ++W RL+++ ++G T V SE
Sbjct: 45 PEDTVTISLKVTLTNLISLNEKEETLTTSVWIGIDWQDYRLNYSKDDFGGIETLRVPSEL 104
Query: 356 LWRPDVVLLNAAATTAG-DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTF 532
+W P++VL N G Y V GSV+W+ + ++++ +P D Q C+
Sbjct: 105 VWLPEIVLENNIDGQFGVAYDANVLVYEGGSVTWLPPAIYRSVCAVEVTYFPFDWQNCSL 164
Query: 533 KFGSRMHXSDEMDF 574
F S+ + ++E++F
Sbjct: 165 IFRSQTYNAEEVEF 178
>M86383-1|AAC84176.1| 502|Homo sapiens nicotinic acetylcholine
receptor alpha 3 subunit precursor protein.
Length = 502
Score = 58.0 bits (134), Expect = 4e-08
Identities = 31/105 (29%), Positives = 55/105 (52%), Gaps = 5/105 (4%)
Frame = +2
Query: 272 LQMNWIGKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYAL----RARVSN 436
L+ W +L WN +G + ++ V ++++W+PD+VL N A GD+ + +A +
Sbjct: 84 LKQIWNDYKLKWNPSGYGGAEFMRVPAQKIWKPDIVLYNNAV---GDFQVTTKTKALLKY 140
Query: 437 NGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXSDEMD 571
G V+WI + + + +P D Q CT KFGS + ++D
Sbjct: 141 TGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKID 185
>Y08421-1|CAA69698.1| 627|Homo sapiens nicotinic acetylcholine
receptor alpha4 subunit precursor protein.
Length = 627
Score = 57.6 bits (133), Expect = 5e-08
Identities = 42/154 (27%), Positives = 75/154 (48%), Gaps = 10/154 (6%)
Frame = +2
Query: 140 MIDSLLATYDRDSPPDSKI--VVNLTLHLRHA---NIRESESTVRIQADLQMNWIGKRLS 304
++ L + Y++ S P + I VV + L A ++ E + ++ W +L
Sbjct: 40 LLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLR 99
Query: 305 WNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNGSVSWIKRLD 469
W+ ++ T + + SE +WRPD+VL N A GD+A+ +A + ++G V W
Sbjct: 100 WDPADYENVTSIRIPSELIWRPDIVLYNNAD---GDFAVTHLTKAHLFHDGRVQWTPPAI 156
Query: 470 ISTPISMQLDNWPNDMQTCTFKFGSRMHXSDEMD 571
+ S+ + +P D Q CT KFGS + ++D
Sbjct: 157 YKSSCSIDVTFFPFDQQNCTMKFGSWTYDKAKID 190
>X89741-1|CAA61893.1| 627|Homo sapiens neuronal acetylcholine
receptor alpha-4 subunit protein.
Length = 627
Score = 57.6 bits (133), Expect = 5e-08
Identities = 42/154 (27%), Positives = 75/154 (48%), Gaps = 10/154 (6%)
Frame = +2
Query: 140 MIDSLLATYDRDSPPDSKI--VVNLTLHLRHA---NIRESESTVRIQADLQMNWIGKRLS 304
++ L + Y++ S P + I VV + L A ++ E + ++ W +L
Sbjct: 40 LLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLR 99
Query: 305 WNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNGSVSWIKRLD 469
W+ ++ T + + SE +WRPD+VL N A GD+A+ +A + ++G V W
Sbjct: 100 WDPADYENVTSIRIPSELIWRPDIVLYNNAD---GDFAVTHLTKAHLFHDGRVQWTPPAI 156
Query: 470 ISTPISMQLDNWPNDMQTCTFKFGSRMHXSDEMD 571
+ S+ + +P D Q CT KFGS + ++D
Sbjct: 157 YKSSCSIDVTFFPFDQQNCTMKFGSWTYDKAKID 190
>X87629-1|CAA60959.1| 602|Homo sapiens nicotinic acetylcholine
receptor protein.
Length = 602
Score = 57.6 bits (133), Expect = 5e-08
Identities = 42/154 (27%), Positives = 75/154 (48%), Gaps = 10/154 (6%)
Frame = +2
Query: 140 MIDSLLATYDRDSPPDSKI--VVNLTLHLRHA---NIRESESTVRIQADLQMNWIGKRLS 304
++ L + Y++ S P + I VV + L A ++ E + ++ W +L
Sbjct: 15 LLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLR 74
Query: 305 WNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNGSVSWIKRLD 469
W+ ++ T + + SE +WRPD+VL N A GD+A+ +A + ++G V W
Sbjct: 75 WDPADYENVTSIRIPSELIWRPDIVLYNNAD---GDFAVTHLTKAHLFHDGRVQWTPPAI 131
Query: 470 ISTPISMQLDNWPNDMQTCTFKFGSRMHXSDEMD 571
+ S+ + +P D Q CT KFGS + ++D
Sbjct: 132 YKSSCSIDVTFFPFDQQNCTMKFGSWTYDKAKID 165
>U62433-1|AAB40111.1| 627|Homo sapiens nicotinic acetylcholine
receptor alpha4 subunit precursor protein.
Length = 627
Score = 57.6 bits (133), Expect = 5e-08
Identities = 42/154 (27%), Positives = 75/154 (48%), Gaps = 10/154 (6%)
Frame = +2
Query: 140 MIDSLLATYDRDSPPDSKI--VVNLTLHLRHA---NIRESESTVRIQADLQMNWIGKRLS 304
++ L + Y++ S P + I VV + L A ++ E + ++ W +L
Sbjct: 40 LLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLR 99
Query: 305 WNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNGSVSWIKRLD 469
W+ ++ T + + SE +WRPD+VL N A GD+A+ +A + ++G V W
Sbjct: 100 WDPADYENVTSIRIPSELIWRPDIVLYNNAD---GDFAVTHLTKAHLFHDGRVQWTPPAI 156
Query: 470 ISTPISMQLDNWPNDMQTCTFKFGSRMHXSDEMD 571
+ S+ + +P D Q CT KFGS + ++D
Sbjct: 157 YKSSCSIDVTFFPFDQQNCTMKFGSWTYDKAKID 190
>L35901-1|AAA64743.1| 627|Homo sapiens nicotinic acetylcholine
receptor alpha 4 subunit protein.
Length = 627
Score = 57.6 bits (133), Expect = 5e-08
Identities = 42/154 (27%), Positives = 75/154 (48%), Gaps = 10/154 (6%)
Frame = +2
Query: 140 MIDSLLATYDRDSPPDSKI--VVNLTLHLRHA---NIRESESTVRIQADLQMNWIGKRLS 304
++ L + Y++ S P + I VV + L A ++ E + ++ W +L
Sbjct: 40 LLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLR 99
Query: 305 WNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNGSVSWIKRLD 469
W+ ++ T + + SE +WRPD+VL N A GD+A+ +A + ++G V W
Sbjct: 100 WDPADYENVTSIRIPSELIWRPDIVLYNNAD---GDFAVTHLTKAHLFHDGRVQWTPPAI 156
Query: 470 ISTPISMQLDNWPNDMQTCTFKFGSRMHXSDEMD 571
+ S+ + +P D Q CT KFGS + ++D
Sbjct: 157 YKSSCSIDVTFFPFDQQNCTMKFGSWTYDKAKID 190
>DQ093071-1|AAY88737.1| 627|Homo sapiens cholinergic receptor,
nicotinic, alpha polypeptide 4 protein.
Length = 627
Score = 57.6 bits (133), Expect = 5e-08
Identities = 42/154 (27%), Positives = 75/154 (48%), Gaps = 10/154 (6%)
Frame = +2
Query: 140 MIDSLLATYDRDSPPDSKI--VVNLTLHLRHA---NIRESESTVRIQADLQMNWIGKRLS 304
++ L + Y++ S P + I VV + L A ++ E + ++ W +L
Sbjct: 40 LLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLR 99
Query: 305 WNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNGSVSWIKRLD 469
W+ ++ T + + SE +WRPD+VL N A GD+A+ +A + ++G V W
Sbjct: 100 WDPADYENVTSIRIPSELIWRPDIVLYNNAD---GDFAVTHLTKAHLFHDGRVQWTPPAI 156
Query: 470 ISTPISMQLDNWPNDMQTCTFKFGSRMHXSDEMD 571
+ S+ + +P D Q CT KFGS + ++D
Sbjct: 157 YKSSCSIDVTFFPFDQQNCTMKFGSWTYDKAKID 190
>BC096290-1|AAH96290.1| 627|Homo sapiens cholinergic receptor,
nicotinic, alpha 4 protein.
Length = 627
Score = 57.6 bits (133), Expect = 5e-08
Identities = 42/154 (27%), Positives = 75/154 (48%), Gaps = 10/154 (6%)
Frame = +2
Query: 140 MIDSLLATYDRDSPPDSKI--VVNLTLHLRHA---NIRESESTVRIQADLQMNWIGKRLS 304
++ L + Y++ S P + I VV + L A ++ E + ++ W +L
Sbjct: 40 LLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLR 99
Query: 305 WNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNGSVSWIKRLD 469
W+ ++ T + + SE +WRPD+VL N A GD+A+ +A + ++G V W
Sbjct: 100 WDPADYENVTSIRIPSELIWRPDIVLYNNAD---GDFAVTHLTKAHLFHDGRVQWTPPAI 156
Query: 470 ISTPISMQLDNWPNDMQTCTFKFGSRMHXSDEMD 571
+ S+ + +P D Q CT KFGS + ++D
Sbjct: 157 YKSSCSIDVTFFPFDQQNCTMKFGSWTYDKAKID 190
>Y00762-1|CAA68731.1| 457|Homo sapiens protein ( Human mRNA for
muscle acetylcholine receptor alpha-subunit. ).
Length = 457
Score = 56.0 bits (129), Expect = 2e-07
Identities = 33/123 (26%), Positives = 60/123 (48%), Gaps = 5/123 (4%)
Frame = +2
Query: 191 KIVVNLTLHLRHANIRESESTVRIQADLQMNWIGKRLSWNAGEWGCSTWL-VSSERLWRP 367
++ V L L ++ N+ E V L+ W+ L WN ++G + + SE++WRP
Sbjct: 50 EVTVGLQL-IQLINVDEVNQIVTTNVRLKQQWVDYNLKWNPDDYGGVKKIHIPSEKIWRP 108
Query: 368 DVVLLNAAATTAGDYAL----RARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFK 535
D+VL N A GD+A+ + + G ++W + + + ++P D Q C+ K
Sbjct: 109 DLVLYNNA---DGDFAIVKFTKVLLQYTGHITWTPPAIFKSYCEIIVTHFPFDEQNCSMK 165
Query: 536 FGS 544
G+
Sbjct: 166 LGT 168
>X02502-1|CAA26344.1| 457|Homo sapiens acetylcholine receptor
protein.
Length = 457
Score = 56.0 bits (129), Expect = 2e-07
Identities = 33/123 (26%), Positives = 60/123 (48%), Gaps = 5/123 (4%)
Frame = +2
Query: 191 KIVVNLTLHLRHANIRESESTVRIQADLQMNWIGKRLSWNAGEWGCSTWL-VSSERLWRP 367
++ V L L ++ N+ E V L+ W+ L WN ++G + + SE++WRP
Sbjct: 50 EVTVGLQL-IQLINVDEVNQIVTTNVRLKQQWVDYNLKWNPDDYGGVKKIHIPSEKIWRP 108
Query: 368 DVVLLNAAATTAGDYAL----RARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFK 535
D+VL N A GD+A+ + + G ++W + + + ++P D Q C+ K
Sbjct: 109 DLVLYNNA---DGDFAIVKFTKVLLQYTGHITWTPPAIFKSYCEIIVTHFPFDEQNCSMK 165
Query: 536 FGS 544
G+
Sbjct: 166 LGT 168
>S77094-1|AAD14247.1| 457|Homo sapiens nicotinic acetylcholine
receptor alpha subunit|AChR protein.
Length = 457
Score = 56.0 bits (129), Expect = 2e-07
Identities = 33/123 (26%), Positives = 60/123 (48%), Gaps = 5/123 (4%)
Frame = +2
Query: 191 KIVVNLTLHLRHANIRESESTVRIQADLQMNWIGKRLSWNAGEWGCSTWL-VSSERLWRP 367
++ V L L ++ N+ E V L+ W+ L WN ++G + + SE++WRP
Sbjct: 50 EVTVGLQL-IQLINVDEVNQIVTTNVRLKQQWVDYNLKWNPDDYGGVKKIHIPSEKIWRP 108
Query: 368 DVVLLNAAATTAGDYAL----RARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFK 535
D+VL N A GD+A+ + + G ++W + + + ++P D Q C+ K
Sbjct: 109 DLVLYNNA---DGDFAIVKFTKVLLQYTGHITWTPPAIFKSYCEIIVTHFPFDEQNCSMK 165
Query: 536 FGS 544
G+
Sbjct: 166 LGT 168
>BC006314-1|AAH06314.1| 269|Homo sapiens CHRNA1 protein protein.
Length = 269
Score = 56.0 bits (129), Expect = 2e-07
Identities = 33/123 (26%), Positives = 60/123 (48%), Gaps = 5/123 (4%)
Frame = +2
Query: 191 KIVVNLTLHLRHANIRESESTVRIQADLQMNWIGKRLSWNAGEWGCSTWL-VSSERLWRP 367
++ V L L ++ N+ E V L+ W+ L WN ++G + + SE++WRP
Sbjct: 50 EVTVGLQL-IQLINVDEVNQIVTTNVRLKQQWVDYNLKWNPDDYGGVKKIHIPSEKIWRP 108
Query: 368 DVVLLNAAATTAGDYAL----RARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFK 535
D+VL N A GD+A+ + + G ++W + + + ++P D Q C+ K
Sbjct: 109 DLVLYNNA---DGDFAIVKFTKVLLQYTGHITWTPPAIFKSYCEIIVTHFPFDEQNCSMK 165
Query: 536 FGS 544
G+
Sbjct: 166 LGT 168
>AC018890-1|AAY14687.1| 457|Homo sapiens unknown protein.
Length = 457
Score = 56.0 bits (129), Expect = 2e-07
Identities = 33/123 (26%), Positives = 60/123 (48%), Gaps = 5/123 (4%)
Frame = +2
Query: 191 KIVVNLTLHLRHANIRESESTVRIQADLQMNWIGKRLSWNAGEWGCSTWL-VSSERLWRP 367
++ V L L ++ N+ E V L+ W+ L WN ++G + + SE++WRP
Sbjct: 50 EVTVGLQL-IQLINVDEVNQIVTTNVRLKQQWVDYNLKWNPDDYGGVKKIHIPSEKIWRP 108
Query: 368 DVVLLNAAATTAGDYAL----RARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFK 535
D+VL N A GD+A+ + + G ++W + + + ++P D Q C+ K
Sbjct: 109 DLVLYNNA---DGDFAIVKFTKVLLQYTGHITWTPPAIFKSYCEIIVTHFPFDEQNCSMK 165
Query: 536 FGS 544
G+
Sbjct: 166 LGT 168
>Y08415-1|CAA69692.1| 502|Homo sapiens nicotinic acetylcholine
receptor beta2 subunit precursor protein.
Length = 502
Score = 55.6 bits (128), Expect = 2e-07
Identities = 36/129 (27%), Positives = 58/129 (44%), Gaps = 3/129 (2%)
Frame = +2
Query: 194 IVVNLTLHLRHA-NIRESESTVRIQADLQMNWIGKRLSWNAGEW-GCSTWLVSSERLWRP 367
+ V L + L ++ E E + L W RL+W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 368 DVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 544
DVVL N A + A VS +GS+ W+ + +++ ++P D Q CT KF S
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRS 175
Query: 545 RMHXSDEMD 571
+ E+D
Sbjct: 176 WTYDRTEID 184
>X53179-1|CAA37320.1| 502|Homo sapiens precursor peptide (AA -25 to
477) protein.
Length = 502
Score = 55.6 bits (128), Expect = 2e-07
Identities = 36/129 (27%), Positives = 58/129 (44%), Gaps = 3/129 (2%)
Frame = +2
Query: 194 IVVNLTLHLRHA-NIRESESTVRIQADLQMNWIGKRLSWNAGEW-GCSTWLVSSERLWRP 367
+ V L + L ++ E E + L W RL+W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 368 DVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 544
DVVL N A + A VS +GS+ W+ + +++ ++P D Q CT KF S
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRS 175
Query: 545 RMHXSDEMD 571
+ E+D
Sbjct: 176 WTYDRTEID 184
>U62437-1|AAB40115.1| 502|Homo sapiens nicotinic acetylcholine
receptor beta2 subunit precursor protein.
Length = 502
Score = 55.6 bits (128), Expect = 2e-07
Identities = 36/129 (27%), Positives = 58/129 (44%), Gaps = 3/129 (2%)
Frame = +2
Query: 194 IVVNLTLHLRHA-NIRESESTVRIQADLQMNWIGKRLSWNAGEW-GCSTWLVSSERLWRP 367
+ V L + L ++ E E + L W RL+W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 368 DVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 544
DVVL N A + A VS +GS+ W+ + +++ ++P D Q CT KF S
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRS 175
Query: 545 RMHXSDEMD 571
+ E+D
Sbjct: 176 WTYDRTEID 184
>DQ644022-1|ABG35128.1| 456|Homo sapiens 5-HT3 receptor subunit E
splice variant HTR3Ea protein.
Length = 456
Score = 55.6 bits (128), Expect = 2e-07
Identities = 28/100 (28%), Positives = 49/100 (49%), Gaps = 1/100 (1%)
Frame = +2
Query: 272 LQMNWIGKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 448
L+M W +SWN E G + ++++ LW PD+ ++ L A VSN G +
Sbjct: 91 LEMVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEGRI 150
Query: 449 SWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXSDEM 568
+ K + + + ++ + +P D Q CT F S ++ D M
Sbjct: 151 RYKKPMKVDSICNLDIFYFPFDQQNCTLTFSSFLYTVDSM 190
>BC101185-1|AAI01186.1| 374|Homo sapiens HTR3E protein protein.
Length = 374
Score = 55.6 bits (128), Expect = 2e-07
Identities = 28/100 (28%), Positives = 49/100 (49%), Gaps = 1/100 (1%)
Frame = +2
Query: 272 LQMNWIGKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 448
L+M W +SWN E G + ++++ LW PD+ ++ L A VSN G +
Sbjct: 20 LEMVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEGRI 79
Query: 449 SWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXSDEM 568
+ K + + + ++ + +P D Q CT F S ++ D M
Sbjct: 80 RYKKPMKVDSICNLDIFYFPFDQQNCTLTFSSFLYTVDSM 119
>BC101183-1|AAI01184.1| 471|Homo sapiens 5-hydroxytryptamine
(serotonin) receptor 3, family member E protein.
Length = 471
Score = 55.6 bits (128), Expect = 2e-07
Identities = 28/100 (28%), Positives = 49/100 (49%), Gaps = 1/100 (1%)
Frame = +2
Query: 272 LQMNWIGKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 448
L+M W +SWN E G + ++++ LW PD+ ++ L A VSN G +
Sbjct: 106 LEMVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEGRI 165
Query: 449 SWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXSDEM 568
+ K + + + ++ + +P D Q CT F S ++ D M
Sbjct: 166 RYKKPMKVDSICNLDIFYFPFDQQNCTLTFSSFLYTVDSM 205
>BC101182-1|AAI01183.1| 471|Homo sapiens 5-hydroxytryptamine
(serotonin) receptor 3, family member E protein.
Length = 471
Score = 55.6 bits (128), Expect = 2e-07
Identities = 28/100 (28%), Positives = 49/100 (49%), Gaps = 1/100 (1%)
Frame = +2
Query: 272 LQMNWIGKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 448
L+M W +SWN E G + ++++ LW PD+ ++ L A VSN G +
Sbjct: 106 LEMVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEGRI 165
Query: 449 SWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXSDEM 568
+ K + + + ++ + +P D Q CT F S ++ D M
Sbjct: 166 RYKKPMKVDSICNLDIFYFPFDQQNCTLTFSSFLYTVDSM 205
>BC075041-1|AAH75041.1| 502|Homo sapiens cholinergic receptor,
nicotinic, beta 2 (neuronal) protein.
Length = 502
Score = 55.6 bits (128), Expect = 2e-07
Identities = 36/129 (27%), Positives = 58/129 (44%), Gaps = 3/129 (2%)
Frame = +2
Query: 194 IVVNLTLHLRHA-NIRESESTVRIQADLQMNWIGKRLSWNAGEW-GCSTWLVSSERLWRP 367
+ V L + L ++ E E + L W RL+W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 368 DVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 544
DVVL N A + A VS +GS+ W+ + +++ ++P D Q CT KF S
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRS 175
Query: 545 RMHXSDEMD 571
+ E+D
Sbjct: 176 WTYDRTEID 184
>BC075040-1|AAH75040.1| 502|Homo sapiens cholinergic receptor,
nicotinic, beta 2 (neuronal) protein.
Length = 502
Score = 55.6 bits (128), Expect = 2e-07
Identities = 36/129 (27%), Positives = 58/129 (44%), Gaps = 3/129 (2%)
Frame = +2
Query: 194 IVVNLTLHLRHA-NIRESESTVRIQADLQMNWIGKRLSWNAGEW-GCSTWLVSSERLWRP 367
+ V L + L ++ E E + L W RL+W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 368 DVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 544
DVVL N A + A VS +GS+ W+ + +++ ++P D Q CT KF S
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRS 175
Query: 545 RMHXSDEMD 571
+ E+D
Sbjct: 176 WTYDRTEID 184
>AY159813-1|AAO38167.2| 471|Homo sapiens 5-hydroxytryptamine
serotonin receptor 3E protein.
Length = 471
Score = 55.6 bits (128), Expect = 2e-07
Identities = 28/100 (28%), Positives = 49/100 (49%), Gaps = 1/100 (1%)
Frame = +2
Query: 272 LQMNWIGKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 448
L+M W +SWN E G + ++++ LW PD+ ++ L A VSN G +
Sbjct: 106 LEMVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEGRI 165
Query: 449 SWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXSDEM 568
+ K + + + ++ + +P D Q CT F S ++ D M
Sbjct: 166 RYKKPMKVDSICNLDIFYFPFDQQNCTLTFSSFLYTVDSM 205
>AL592078-3|CAI16184.1| 502|Homo sapiens cholinergic receptor,
nicotinic, beta 2 (neuronal) protein.
Length = 502
Score = 55.6 bits (128), Expect = 2e-07
Identities = 36/129 (27%), Positives = 58/129 (44%), Gaps = 3/129 (2%)
Frame = +2
Query: 194 IVVNLTLHLRHA-NIRESESTVRIQADLQMNWIGKRLSWNAGEW-GCSTWLVSSERLWRP 367
+ V L + L ++ E E + L W RL+W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 368 DVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 544
DVVL N A + A VS +GS+ W+ + +++ ++P D Q CT KF S
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRS 175
Query: 545 RMHXSDEMD 571
+ E+D
Sbjct: 176 WTYDRTEID 184
>AJ295237-1|CAC16144.1| 450|Homo sapiens neuronal nicotinic
acetylcholine receptor subunit4 protein.
Length = 450
Score = 55.6 bits (128), Expect = 2e-07
Identities = 45/167 (26%), Positives = 71/167 (42%), Gaps = 10/167 (5%)
Frame = +2
Query: 107 AEC---ENATSLSLMIDSLLATYDRDSPP--DSKIVVNLTLHLRHANI---RESESTVRI 262
AEC E +L L D L A Y P D+ +N+TL + + I E + +
Sbjct: 20 AECLGAEGRLALKLFRD-LFANYTSALRPVADTDQTLNVTLEVTLSQIIDMDERNQVLTL 78
Query: 263 QADLQMNWIGKRLSWNAGEWG-CSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSN 436
++ W L W+ +G + S +WRPD+VL N A A G + + +
Sbjct: 79 YLWIRQEWTDAYLRWDPNAYGGLDAIRIPSSLVWRPDIVLYNKADAQPPGSASTNVVLRH 138
Query: 437 NGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXSDEMDFR 577
+G+V W + + + +P D Q C FGS H ++D R
Sbjct: 139 DGAVRWDAPAITRSSCRVDVAAFPFDAQHCGLTFGSWTHGGHQLDVR 185
>AJ278118-1|CAC20435.1| 450|Homo sapiens neuronal nicotinic
acetylcholine alpha10 subunit protein.
Length = 450
Score = 55.6 bits (128), Expect = 2e-07
Identities = 45/167 (26%), Positives = 71/167 (42%), Gaps = 10/167 (5%)
Frame = +2
Query: 107 AEC---ENATSLSLMIDSLLATYDRDSPP--DSKIVVNLTLHLRHANI---RESESTVRI 262
AEC E +L L D L A Y P D+ +N+TL + + I E + +
Sbjct: 20 AECLGAEGRLALKLFRD-LFANYTSALRPVADTDQTLNVTLEVTLSQIIDMDERNQVLTL 78
Query: 263 QADLQMNWIGKRLSWNAGEWG-CSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSN 436
++ W L W+ +G + S +WRPD+VL N A A G + + +
Sbjct: 79 YLWIRQEWTDAYLRWDPNAYGGLDAIRIPSSLVWRPDIVLYNKADAQPPGSASTNVVLRH 138
Query: 437 NGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXSDEMDFR 577
+G+V W + + + +P D Q C FGS H ++D R
Sbjct: 139 DGAVRWDAPAITRSSCRVDVAAFPFDAQHCGLTFGSWTHGGHQLDVR 185
>AJ001935-1|CAA05108.1| 504|Homo sapiens CHRNB2 protein.
Length = 504
Score = 55.6 bits (128), Expect = 2e-07
Identities = 36/129 (27%), Positives = 58/129 (44%), Gaps = 3/129 (2%)
Frame = +2
Query: 194 IVVNLTLHLRHA-NIRESESTVRIQADLQMNWIGKRLSWNAGEW-GCSTWLVSSERLWRP 367
+ V L + L ++ E E + L W RL+W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 368 DVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 544
DVVL N A + A VS +GS+ W+ + +++ ++P D Q CT KF S
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRS 175
Query: 545 RMHXSDEMD 571
+ E+D
Sbjct: 176 WTYDRTEID 184
>AF327367-1|AAK14333.1| 450|Homo sapiens nicotinic acetylcholine
receptor subunit alpha 10 protein.
Length = 450
Score = 55.6 bits (128), Expect = 2e-07
Identities = 45/167 (26%), Positives = 71/167 (42%), Gaps = 10/167 (5%)
Frame = +2
Query: 107 AEC---ENATSLSLMIDSLLATYDRDSPP--DSKIVVNLTLHLRHANI---RESESTVRI 262
AEC E +L L D L A Y P D+ +N+TL + + I E + +
Sbjct: 20 AECLGAEGRLALKLFRD-LFANYTSALRPVADTDQTLNVTLEVTLSQIIDMDERNQVLTL 78
Query: 263 QADLQMNWIGKRLSWNAGEWG-CSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSN 436
++ W L W+ +G + S +WRPD+VL N A A G + + +
Sbjct: 79 YLWIRQEWTDAYLRWDPNAYGGLDAIRIPSSLVWRPDIVLYNKADAQPPGSASTNVVLRH 138
Query: 437 NGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXSDEMDFR 577
+G+V W + + + +P D Q C FGS H ++D R
Sbjct: 139 DGAVRWDAPAITRSSCRVDVAAFPFDAQHCGLTFGSWTHGGHQLDVR 185
>AF199235-1|AAG00795.2| 450|Homo sapiens nicotinic acetylcholine
receptor subunit alpha 10 protein.
Length = 450
Score = 55.6 bits (128), Expect = 2e-07
Identities = 45/167 (26%), Positives = 71/167 (42%), Gaps = 10/167 (5%)
Frame = +2
Query: 107 AEC---ENATSLSLMIDSLLATYDRDSPP--DSKIVVNLTLHLRHANI---RESESTVRI 262
AEC E +L L D L A Y P D+ +N+TL + + I E + +
Sbjct: 20 AECLGAEGRLALKLFRD-LFANYTSALRPVADTDQTLNVTLEVTLSQIIDMDERNQVLTL 78
Query: 263 QADLQMNWIGKRLSWNAGEWG-CSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSN 436
++ W L W+ +G + S +WRPD+VL N A A G + + +
Sbjct: 79 YLWIRQEWTDAYLRWDPNAYGGLDAIRIPSSLVWRPDIVLYNKADAQPPGSASTNVVLRH 138
Query: 437 NGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXSDEMDFR 577
+G+V W + + + +P D Q C FGS H ++D R
Sbjct: 139 DGAVRWDAPAITRSSCRVDVAAFPFDAQHCGLTFGSWTHGGHQLDVR 185
>AF077186-1|AAD45422.1| 502|Homo sapiens neuronal nicotinic
acetylcholine receptor beta 2 protein.
Length = 502
Score = 55.6 bits (128), Expect = 2e-07
Identities = 36/129 (27%), Positives = 58/129 (44%), Gaps = 3/129 (2%)
Frame = +2
Query: 194 IVVNLTLHLRHA-NIRESESTVRIQADLQMNWIGKRLSWNAGEW-GCSTWLVSSERLWRP 367
+ V L + L ++ E E + L W RL+W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 368 DVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 544
DVVL N A + A VS +GS+ W+ + +++ ++P D Q CT KF S
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRS 175
Query: 545 RMHXSDEMD 571
+ E+D
Sbjct: 176 WTYDRTEID 184
>X55019-1|CAA38759.1| 517|Homo sapiens acetylcholine receptor delta
subunit protein.
Length = 517
Score = 54.0 bits (124), Expect = 7e-07
Identities = 34/131 (25%), Positives = 61/131 (46%), Gaps = 3/131 (2%)
Frame = +2
Query: 185 DSKIVVNLTLHLRHA-NIRESESTVRIQADLQMNWIGKRLSWNAGEWG-CSTWLVSSERL 358
+ + V L L L + +++E E T+ ++ W RL WNA E+G S + + +
Sbjct: 49 EESVDVALALTLSNLISLKEVEETLTTNVWIEHGWTDNRLKWNAEEFGNISVLRLPPDMV 108
Query: 359 WRPDVVL-LNAAATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFK 535
W P++VL N + Y+ V + G V W+ + + + +P D Q C+ K
Sbjct: 109 WLPEIVLENNNDGSFQISYSCNVLVYHYGFVYWLPPAIFRSSCPISVTYFPFDWQNCSLK 168
Query: 536 FGSRMHXSDEM 568
F S + + E+
Sbjct: 169 FSSLKYTAKEI 179
>BC131799-1|AAI31800.1| 447|Homo sapiens 5-hydroxytryptamine
(serotonin) receptor 3, family member C protein.
Length = 447
Score = 54.0 bits (124), Expect = 7e-07
Identities = 26/100 (26%), Positives = 50/100 (50%), Gaps = 1/100 (1%)
Frame = +2
Query: 272 LQMNWIGKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 448
+ + W ++WN E G + V +E LW PD+ ++ + L A +S+ G +
Sbjct: 91 MDLVWDNPFINWNPKECVGINKLTVLAENLWLPDIFIVESMDVDQTPSGLTAYISSEGRI 150
Query: 449 SWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXSDEM 568
+ K + +++ ++ + +P D Q CTF F S ++ D M
Sbjct: 151 KYDKPMRVTSICNLDIFYFPFDQQNCTFTFSSFLYTVDSM 190
>BC093925-1|AAH93925.1| 517|Homo sapiens cholinergic receptor,
nicotinic, delta protein.
Length = 517
Score = 54.0 bits (124), Expect = 7e-07
Identities = 34/131 (25%), Positives = 61/131 (46%), Gaps = 3/131 (2%)
Frame = +2
Query: 185 DSKIVVNLTLHLRHA-NIRESESTVRIQADLQMNWIGKRLSWNAGEWG-CSTWLVSSERL 358
+ + V L L L + +++E E T+ ++ W RL WNA E+G S + + +
Sbjct: 49 EESVDVALALTLSNLISLKEVEETLTTNVWIEHGWTDNRLKWNAEEFGNISVLRLPPDMV 108
Query: 359 WRPDVVL-LNAAATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFK 535
W P++VL N + Y+ V + G V W+ + + + +P D Q C+ K
Sbjct: 109 WLPEIVLENNNDGSFQISYSCNVLVYHYGFVYWLPPAIFRSSCPISVTYFPFDWQNCSLK 168
Query: 536 FGSRMHXSDEM 568
F S + + E+
Sbjct: 169 FSSLKYTAKEI 179
>BC093923-1|AAH93923.1| 517|Homo sapiens cholinergic receptor,
nicotinic, delta protein.
Length = 517
Score = 54.0 bits (124), Expect = 7e-07
Identities = 34/131 (25%), Positives = 61/131 (46%), Gaps = 3/131 (2%)
Frame = +2
Query: 185 DSKIVVNLTLHLRHA-NIRESESTVRIQADLQMNWIGKRLSWNAGEWG-CSTWLVSSERL 358
+ + V L L L + +++E E T+ ++ W RL WNA E+G S + + +
Sbjct: 49 EESVDVALALTLSNLISLKEVEETLTTNVWIEHGWTDNRLKWNAEEFGNISVLRLPPDMV 108
Query: 359 WRPDVVL-LNAAATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFK 535
W P++VL N + Y+ V + G V W+ + + + +P D Q C+ K
Sbjct: 109 WLPEIVLENNNDGSFQISYSCNVLVYHYGFVYWLPPAIFRSSCPISVTYFPFDWQNCSLK 168
Query: 536 FGSRMHXSDEM 568
F S + + E+
Sbjct: 169 FSSLKYTAKEI 179
>AY349353-1|AAQ93477.1| 456|Homo sapiens 5-HT3c1 serotonin
receptor-like protein protein.
Length = 456
Score = 54.0 bits (124), Expect = 7e-07
Identities = 28/104 (26%), Positives = 50/104 (48%), Gaps = 1/104 (0%)
Frame = +2
Query: 260 IQADLQMNWIGKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSN 436
+ A L + W +SWN E G + ++++ LW PD+ ++ L A VSN
Sbjct: 87 MSAILDVVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSN 146
Query: 437 NGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXSDEM 568
G + + K + + + ++ + +P D Q CT F S ++ D M
Sbjct: 147 EGRIRYKKPMKVDSICNLDIFYFPFDQQNCTLTFSSFLYTVDSM 190
>AY349352-1|AAQ93476.1| 441|Homo sapiens 5-HT3c1 serotonin
receptor-like protein protein.
Length = 441
Score = 54.0 bits (124), Expect = 7e-07
Identities = 28/104 (26%), Positives = 50/104 (48%), Gaps = 1/104 (0%)
Frame = +2
Query: 260 IQADLQMNWIGKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSN 436
+ A L + W +SWN E G + ++++ LW PD+ ++ L A VSN
Sbjct: 72 MSAILDVVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSN 131
Query: 437 NGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXSDEM 568
G + + K + + + ++ + +P D Q CT F S ++ D M
Sbjct: 132 EGRIRYKKPMKVDSICNLDIFYFPFDQQNCTLTFSSFLYTVDSM 175
>AC092165-2|AAY24102.1| 517|Homo sapiens unknown protein.
Length = 517
Score = 54.0 bits (124), Expect = 7e-07
Identities = 34/131 (25%), Positives = 61/131 (46%), Gaps = 3/131 (2%)
Frame = +2
Query: 185 DSKIVVNLTLHLRHA-NIRESESTVRIQADLQMNWIGKRLSWNAGEWG-CSTWLVSSERL 358
+ + V L L L + +++E E T+ ++ W RL WNA E+G S + + +
Sbjct: 49 EESVDVALALTLSNLISLKEVEETLTTNVWIEHGWTDNRLKWNAEEFGNISVLRLPPDMV 108
Query: 359 WRPDVVL-LNAAATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFK 535
W P++VL N + Y+ V + G V W+ + + + +P D Q C+ K
Sbjct: 109 WLPEIVLENNNDGSFQISYSCNVLVYHYGFVYWLPPAIFRSSCPISVTYFPFDWQNCSLK 168
Query: 536 FGSRMHXSDEM 568
F S + + E+
Sbjct: 169 FSSLKYTAKEI 179
>AF459285-1|AAL66182.1| 447|Homo sapiens 5-hydroxytryptamine
receptor 3 subunit C protein.
Length = 447
Score = 53.6 bits (123), Expect = 9e-07
Identities = 26/100 (26%), Positives = 49/100 (49%), Gaps = 1/100 (1%)
Frame = +2
Query: 272 LQMNWIGKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 448
+ + W ++WN E G + V +E LW PD+ ++ + L A +S+ G +
Sbjct: 91 MDLVWDNPFINWNPKECVGINKLTVLAENLWLPDIFIVESMDVDQTPSGLTAYISSEGRI 150
Query: 449 SWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXSDEM 568
+ K + +++ + + +P D Q CTF F S ++ D M
Sbjct: 151 KYDKPMRVTSICKLDIFYFPFDQQNCTFTFSSFLYTVDSM 190
>BC110597-1|AAI10598.1| 411|Homo sapiens ligand-gated ion channel,
zinc activated 1 protein.
Length = 411
Score = 51.6 bits (118), Expect = 4e-06
Identities = 27/102 (26%), Positives = 49/102 (48%)
Frame = +2
Query: 272 LQMNWIGKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVS 451
L+++W+ RL+WN + E LW P + +L A D + +ARV +G V
Sbjct: 86 LRLSWLDTRLAWNTSAHPRHAITLPWESLWTPRLTILEALWVDWRDQSPQARVDQDGHVK 145
Query: 452 WIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXSDEMDFR 577
L T + +L ++P D C+ F + + + E++F+
Sbjct: 146 LNLALTTETNCNFELLHFPRDHSNCSLSFYALSNTAMELEFQ 187
>AF512521-1|AAO20969.1| 411|Homo sapiens ligand-gated ion channel
subunit protein.
Length = 411
Score = 51.6 bits (118), Expect = 4e-06
Identities = 27/102 (26%), Positives = 49/102 (48%)
Frame = +2
Query: 272 LQMNWIGKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVS 451
L+++W+ RL+WN + E LW P + +L A D + +ARV +G V
Sbjct: 86 LRLSWLDTRLAWNTSAHPRHAITLPWESLWTPRLTILEALWVDWRDQSPQARVDQDGHVK 145
Query: 452 WIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXSDEMDFR 577
L T + +L ++P D C+ F + + + E++F+
Sbjct: 146 LNLALTTETNCNFELLHFPRDHSNCSLSFYALSNTAMELEFQ 187
>AB223030-1|BAE19924.1| 411|Homo sapiens ligand-gated ion-channel
receptor L2 protein.
Length = 411
Score = 51.2 bits (117), Expect = 5e-06
Identities = 27/102 (26%), Positives = 49/102 (48%)
Frame = +2
Query: 272 LQMNWIGKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVS 451
L+++W+ RL+WN + E LW P + +L A D + +ARV +G V
Sbjct: 86 LRLSWLDTRLAWNTSAHPRHAITLPWESLWTPRLTILEALWVDWRDQSPQARVDQDGHVK 145
Query: 452 WIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXSDEMDFR 577
L T + +L ++P D C+ F + + + E++F+
Sbjct: 146 LNLALATETNCNFELLHFPRDHSNCSLSFYALSNTAMELEFQ 187
>L08485-1|AAA58490.1| 462|Homo sapiens GABA-benzodiazepine receptor
alpha-5-subunit protein.
Length = 462
Score = 50.8 bits (116), Expect = 6e-06
Identities = 37/158 (23%), Positives = 70/158 (44%), Gaps = 7/158 (4%)
Frame = +2
Query: 116 ENATSLSLMIDSLLATYDRDSPPD--SKIV-VNLTLHLRHAN-IRESESTVRIQADLQMN 283
+N T + ++D LL YD P +I V +++ + ++E I + +
Sbjct: 44 DNITIFTRILDGLLDGYDNRLRPGLGERITQVRTDIYVTSFGPVSDTEMEYTIDVFFRQS 103
Query: 284 WIGKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSW 454
W +RL + + + ++W PD N + A + R+ ++G++ +
Sbjct: 104 WKDERLRFKGPMQRLPLNNLLASKIWTPDTFFHNGKKSIAHNMTTPNKLLRLEDDGTLLY 163
Query: 455 IKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXSDEM 568
RL IS MQL+++P D C KFGS + + E+
Sbjct: 164 TMRLTISAECPMQLEDFPMDAHACPLKFGSYAYPNSEV 201
>BT009830-1|AAP88832.1| 462|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 5 protein.
Length = 462
Score = 50.8 bits (116), Expect = 6e-06
Identities = 37/158 (23%), Positives = 70/158 (44%), Gaps = 7/158 (4%)
Frame = +2
Query: 116 ENATSLSLMIDSLLATYDRDSPPD--SKIV-VNLTLHLRHAN-IRESESTVRIQADLQMN 283
+N T + ++D LL YD P +I V +++ + ++E I + +
Sbjct: 44 DNITIFTRILDGLLDGYDNRLRPGLGERITQVRTDIYVTSFGPVSDTEMEYTIDVFFRQS 103
Query: 284 WIGKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSW 454
W +RL + + + ++W PD N + A + R+ ++G++ +
Sbjct: 104 WKDERLRFKGPMQRLPLNNLLASKIWTPDTFFHNGKKSIAHNMTTPNKLLRLEDDGTLLY 163
Query: 455 IKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXSDEM 568
RL IS MQL+++P D C KFGS + + E+
Sbjct: 164 TMRLTISAECPMQLEDFPMDAHACPLKFGSYAYPNSEV 201
>BC113575-1|AAI13576.1| 479|Homo sapiens cholinergic receptor,
nicotinic, alpha 9 protein.
Length = 479
Score = 50.8 bits (116), Expect = 6e-06
Identities = 36/163 (22%), Positives = 73/163 (44%), Gaps = 7/163 (4%)
Frame = +2
Query: 104 AAECENATSLSLMIDSLLATYDRDSPP--DSKIVVNLTLHLRHANIRESESTVRIQAD-- 271
AAE + + + L Y P D+ V+N+TL + + I++ + +I
Sbjct: 22 AAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQITLSQIKDMDERNQILTAYL 81
Query: 272 -LQMNWIGKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGD-YALRARVSNNG 442
++ W L+W+ ++ G + + S+ +WRPD+VL N A + + + +G
Sbjct: 82 WIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKADDESSEPVNTNVVLRYDG 141
Query: 443 SVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXSDEMD 571
++W + + + +P D Q C FGS + +++D
Sbjct: 142 LITWDAPAITKSSCVVDVTYFPFDNQQCNLTFGSWTYNGNQVD 184
>BC113549-1|AAI13550.1| 479|Homo sapiens cholinergic receptor,
nicotinic, alpha 9 protein.
Length = 479
Score = 50.8 bits (116), Expect = 6e-06
Identities = 36/163 (22%), Positives = 73/163 (44%), Gaps = 7/163 (4%)
Frame = +2
Query: 104 AAECENATSLSLMIDSLLATYDRDSPP--DSKIVVNLTLHLRHANIRESESTVRIQAD-- 271
AAE + + + L Y P D+ V+N+TL + + I++ + +I
Sbjct: 22 AAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQITLSQIKDMDERNQILTAYL 81
Query: 272 -LQMNWIGKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGD-YALRARVSNNG 442
++ W L+W+ ++ G + + S+ +WRPD+VL N A + + + +G
Sbjct: 82 WIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKADDESSEPVNTNVVLRYDG 141
Query: 443 SVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXSDEMD 571
++W + + + +P D Q C FGS + +++D
Sbjct: 142 LITWDAPAITKSSCVVDVTYFPFDNQQCNLTFGSWTYNGNQVD 184
>BC113422-1|AAI13423.1| 462|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 5 protein.
Length = 462
Score = 50.8 bits (116), Expect = 6e-06
Identities = 37/158 (23%), Positives = 70/158 (44%), Gaps = 7/158 (4%)
Frame = +2
Query: 116 ENATSLSLMIDSLLATYDRDSPPD--SKIV-VNLTLHLRHAN-IRESESTVRIQADLQMN 283
+N T + ++D LL YD P +I V +++ + ++E I + +
Sbjct: 44 DNITIFTRILDGLLDGYDNRLRPGLGERITQVRTDIYVTSFGPVSDTEMEYTIDVFFRQS 103
Query: 284 WIGKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSW 454
W +RL + + + ++W PD N + A + R+ ++G++ +
Sbjct: 104 WKDERLRFKGPMQRLPLNNLLASKIWTPDTFFHNGKKSIAHNMTTPNKLLRLEDDGTLLY 163
Query: 455 IKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXSDEM 568
RL IS MQL+++P D C KFGS + + E+
Sbjct: 164 TMRLTISAECPMQLEDFPMDAHACPLKFGSYAYPNSEV 201
>BC111979-1|AAI11980.1| 462|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 5, precursor protein.
Length = 462
Score = 50.8 bits (116), Expect = 6e-06
Identities = 37/158 (23%), Positives = 70/158 (44%), Gaps = 7/158 (4%)
Frame = +2
Query: 116 ENATSLSLMIDSLLATYDRDSPPD--SKIV-VNLTLHLRHAN-IRESESTVRIQADLQMN 283
+N T + ++D LL YD P +I V +++ + ++E I + +
Sbjct: 44 DNITIFTRILDGLLDGYDNRLRPGLGERITQVRTDIYVTSFGPVSDTEMEYTIDVFFRQS 103
Query: 284 WIGKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSW 454
W +RL + + + ++W PD N + A + R+ ++G++ +
Sbjct: 104 WKDERLRFKGPMQRLPLNNLLASKIWTPDTFFHNGKKSIAHNMTTPNKLLRLEDDGTLLY 163
Query: 455 IKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXSDEM 568
RL IS MQL+++P D C KFGS + + E+
Sbjct: 164 TMRLTISAECPMQLEDFPMDAHACPLKFGSYAYPNSEV 201
>AY123244-1|AAM74523.1| 479|Homo sapiens nicotinic acetylcholine
receptor subunit alpha 9 protein.
Length = 479
Score = 50.8 bits (116), Expect = 6e-06
Identities = 36/163 (22%), Positives = 73/163 (44%), Gaps = 7/163 (4%)
Frame = +2
Query: 104 AAECENATSLSLMIDSLLATYDRDSPP--DSKIVVNLTLHLRHANIRESESTVRIQAD-- 271
AAE + + + L Y P D+ V+N+TL + + I++ + +I
Sbjct: 22 AAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQITLSQIKDMDERNQILTAYL 81
Query: 272 -LQMNWIGKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGD-YALRARVSNNG 442
++ W L+W+ ++ G + + S+ +WRPD+VL N A + + + +G
Sbjct: 82 WIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKADDESSEPVNTNVVLRYDG 141
Query: 443 SVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXSDEMD 571
++W + + + +P D Q C FGS + +++D
Sbjct: 142 LITWDAPAITKSSCVVDVTYFPFDNQQCNLTFGSWTYNGNQVD 184
>AJ243342-1|CAB65091.1| 479|Homo sapiens nicotinic acetylcholine
receptor alpha 9 subunit protein.
Length = 479
Score = 50.8 bits (116), Expect = 6e-06
Identities = 36/163 (22%), Positives = 73/163 (44%), Gaps = 7/163 (4%)
Frame = +2
Query: 104 AAECENATSLSLMIDSLLATYDRDSPP--DSKIVVNLTLHLRHANIRESESTVRIQAD-- 271
AAE + + + L Y P D+ V+N+TL + + I++ + +I
Sbjct: 22 AAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQITLSQIKDMDERNQILTAYL 81
Query: 272 -LQMNWIGKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGD-YALRARVSNNG 442
++ W L+W+ ++ G + + S+ +WRPD+VL N A + + + +G
Sbjct: 82 WIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKADDESSEPVNTNVVLRYDG 141
Query: 443 SVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXSDEMD 571
++W + + + +P D Q C FGS + +++D
Sbjct: 142 LITWDAPAITKSSCVVDVTYFPFDNQQCNLTFGSWTYNGNQVD 184
>AF227732-1|AAF61920.1| 470|Homo sapiens nicotinic acetylcholine
receptor alpha 9 subunit protein.
Length = 470
Score = 50.8 bits (116), Expect = 6e-06
Identities = 36/163 (22%), Positives = 73/163 (44%), Gaps = 7/163 (4%)
Frame = +2
Query: 104 AAECENATSLSLMIDSLLATYDRDSPP--DSKIVVNLTLHLRHANIRESESTVRIQAD-- 271
AAE + + + L Y P D+ V+N+TL + + I++ + +I
Sbjct: 16 AAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQITLSQIKDMDERNQILTAYL 75
Query: 272 -LQMNWIGKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGD-YALRARVSNNG 442
++ W L+W+ ++ G + + S+ +WRPD+VL N A + + + +G
Sbjct: 76 WIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKADDESSEPVNTNVVLRYDG 135
Query: 443 SVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXSDEMD 571
++W + + + +P D Q C FGS + +++D
Sbjct: 136 LITWDAPAITKSSCVVDVTYFPFDNQQCNLTFGSWTYNGNQVD 178
>AC118275-1|AAY40986.1| 479|Homo sapiens unknown protein.
Length = 479
Score = 50.8 bits (116), Expect = 6e-06
Identities = 36/163 (22%), Positives = 73/163 (44%), Gaps = 7/163 (4%)
Frame = +2
Query: 104 AAECENATSLSLMIDSLLATYDRDSPP--DSKIVVNLTLHLRHANIRESESTVRIQAD-- 271
AAE + + + L Y P D+ V+N+TL + + I++ + +I
Sbjct: 22 AAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQITLSQIKDMDERNQILTAYL 81
Query: 272 -LQMNWIGKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGD-YALRARVSNNG 442
++ W L+W+ ++ G + + S+ +WRPD+VL N A + + + +G
Sbjct: 82 WIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKADDESSEPVNTNVVLRYDG 141
Query: 443 SVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXSDEMD 571
++W + + + +P D Q C FGS + +++D
Sbjct: 142 LITWDAPAITKSSCVVDVTYFPFDNQQCNLTFGSWTYNGNQVD 184
>Z23141-1|CAA80672.1| 479|Homo sapiens cholinergic receptor,
nicotinic, alpha polypeptide 7 protein.
Length = 479
Score = 50.0 bits (114), Expect = 1e-05
Identities = 34/137 (24%), Positives = 64/137 (46%), Gaps = 2/137 (1%)
Frame = +2
Query: 173 DSPPDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIGKRLSWNAGEW-GCSTWLVSS 349
DS P + + +L+L L+ ++ E + LQM+W L WN E+ G T
Sbjct: 24 DSQPLT-VYFSLSL-LQIMDVDEKNQVLTTNIWLQMSWTDHYLQWNVSEYPGVKTVRFPD 81
Query: 350 ERLWRPDVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTC 526
++W+PD++L N+A + V+++G ++ + + + +P D+Q C
Sbjct: 82 GQIWKPDILLYNSADERFDATFHTNVLVNSSGHCQYLPPGIFKSSCYIDVRWFPFDVQHC 141
Query: 527 TFKFGSRMHXSDEMDFR 577
KFGS + +D +
Sbjct: 142 KLKFGSWSYGGWSLDLQ 158
>Y08420-1|CAA69697.1| 502|Homo sapiens nicotinic acetylcholine
receptor alpha7 subunit precursor protein.
Length = 502
Score = 50.0 bits (114), Expect = 1e-05
Identities = 34/137 (24%), Positives = 64/137 (46%), Gaps = 2/137 (1%)
Frame = +2
Query: 173 DSPPDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIGKRLSWNAGEW-GCSTWLVSS 349
DS P + + +L+L L+ ++ E + LQM+W L WN E+ G T
Sbjct: 47 DSQPLT-VYFSLSL-LQIMDVDEKNQVLTTNIWLQMSWTDHYLQWNVSEYPGVKTVRFPD 104
Query: 350 ERLWRPDVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTC 526
++W+PD++L N+A + V+++G ++ + + + +P D+Q C
Sbjct: 105 GQIWKPDILLYNSADERFDATFHTNVLVNSSGHCQYLPPGIFKSSCYIDVRWFPFDVQHC 164
Query: 527 TFKFGSRMHXSDEMDFR 577
KFGS + +D +
Sbjct: 165 KLKFGSWSYGGWSLDLQ 181
>X70297-1|CAA49778.1| 502|Homo sapiens neuronal nicotinic
acetylocholine receptor alpha-7 subunit protein.
Length = 502
Score = 50.0 bits (114), Expect = 1e-05
Identities = 34/137 (24%), Positives = 64/137 (46%), Gaps = 2/137 (1%)
Frame = +2
Query: 173 DSPPDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIGKRLSWNAGEW-GCSTWLVSS 349
DS P + + +L+L L+ ++ E + LQM+W L WN E+ G T
Sbjct: 47 DSQPLT-VYFSLSL-LQIMDVDEKNQVLTTNIWLQMSWTDHYLQWNVSEYPGVKTVRFPD 104
Query: 350 ERLWRPDVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTC 526
++W+PD++L N+A + V+++G ++ + + + +P D+Q C
Sbjct: 105 GQIWKPDILLYNSADERFDATFHTNVLVNSSGHCQYLPPGIFKSSCYIDVRWFPFDVQHC 164
Query: 527 TFKFGSRMHXSDEMDFR 577
KFGS + +D +
Sbjct: 165 KLKFGSWSYGGWSLDLQ 181
>U62436-1|AAB40114.1| 502|Homo sapiens nicotinic acetylcholine
receptor alpha7 subunit precursor protein.
Length = 502
Score = 50.0 bits (114), Expect = 1e-05
Identities = 34/137 (24%), Positives = 64/137 (46%), Gaps = 2/137 (1%)
Frame = +2
Query: 173 DSPPDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIGKRLSWNAGEW-GCSTWLVSS 349
DS P + + +L+L L+ ++ E + LQM+W L WN E+ G T
Sbjct: 47 DSQPLT-VYFSLSL-LQIMDVDEKNQVLTTNIWLQMSWTDHYLQWNVSEYPGVKTVRFPD 104
Query: 350 ERLWRPDVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTC 526
++W+PD++L N+A + V+++G ++ + + + +P D+Q C
Sbjct: 105 GQIWKPDILLYNSADERFDATFHTNVLVNSSGHCQYLPPGIFKSSCYIDVRWFPFDVQHC 164
Query: 527 TFKFGSRMHXSDEMDFR 577
KFGS + +D +
Sbjct: 165 KLKFGSWSYGGWSLDLQ 181
>S82769-1|AAB39369.1| 467|Homo sapiens GABAA receptor gamma 3
subunit protein.
Length = 467
Score = 50.0 bits (114), Expect = 1e-05
Identities = 37/158 (23%), Positives = 68/158 (43%), Gaps = 7/158 (4%)
Frame = +2
Query: 125 TSLSLMIDSLLATYDRDSPPDSKI---VVNLTLHLRHAN-IRESESTVRIQADLQMNWIG 292
T ++L+++ LL YD+ PD I V+++ +++ + +I W
Sbjct: 45 TDVTLILNKLLREYDKKLRPDIGIKPTVIDVDIYVNSIGPVSSINMEYQIDIFFAQTWTD 104
Query: 293 KRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKR 463
RL +N+ + +W PD + N+ A R+ N+G + + R
Sbjct: 105 SRLRFNSTMKILTLNSNMVGLIWIPDTIFRNSKTAEAHWITTPNQLLRIWNDGKILYTLR 164
Query: 464 LDISTPISMQLDNWPNDMQTCTFKFGSRMHXSDEMDFR 577
L I+ +QL N+P D +C F S + +EM +R
Sbjct: 165 LTINAECQLQLHNFPMDEHSCPLIFSSYGYPKEEMIYR 202
>AJ586911-1|CAE52911.1| 502|Homo sapiens nicotinic acetylcholine
alpha-7 subunit protein.
Length = 502
Score = 50.0 bits (114), Expect = 1e-05
Identities = 34/137 (24%), Positives = 64/137 (46%), Gaps = 2/137 (1%)
Frame = +2
Query: 173 DSPPDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIGKRLSWNAGEW-GCSTWLVSS 349
DS P + + +L+L L+ ++ E + LQM+W L WN E+ G T
Sbjct: 47 DSQPLT-VYFSLSL-LQIMDVDEKNQVLTTNIWLQMSWTDHYLQWNVSEYPGVKTVRFPD 104
Query: 350 ERLWRPDVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTC 526
++W+PD++L N+A + V+++G ++ + + + +P D+Q C
Sbjct: 105 GQIWKPDILLYNSADERFDATFHTNVLVNSSGHCQYLPPGIFKSSCYIDVRWFPFDVQHC 164
Query: 527 TFKFGSRMHXSDEMDFR 577
KFGS + +D +
Sbjct: 165 KLKFGSWSYGGWSLDLQ 181
>AF269144-1|AAF99698.1| 467|Homo sapiens GABAA receptor gamma 3
subunit protein.
Length = 467
Score = 50.0 bits (114), Expect = 1e-05
Identities = 37/158 (23%), Positives = 68/158 (43%), Gaps = 7/158 (4%)
Frame = +2
Query: 125 TSLSLMIDSLLATYDRDSPPDSKI---VVNLTLHLRHAN-IRESESTVRIQADLQMNWIG 292
T ++L+++ LL YD+ PD I V+++ +++ + +I W
Sbjct: 45 TDVTLILNKLLREYDKKLRPDIGIKPTVIDVDIYVNSIGPVSSINMEYQIDIFFAQTWTD 104
Query: 293 KRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKR 463
RL +N+ + +W PD + N+ A R+ N+G + + R
Sbjct: 105 SRLRFNSTMKILTLNSNMVGLIWIPDTIFRNSKTAEAHWITTPNQLLRIWNDGKILYTLR 164
Query: 464 LDISTPISMQLDNWPNDMQTCTFKFGSRMHXSDEMDFR 577
L I+ +QL N+P D +C F S + +EM +R
Sbjct: 165 LTINAECQLQLHNFPMDEHSCPLIFSSYGYPKEEMIYR 202
>AF228458-1|AAF63215.1| 449|Homo sapiens GABAA receptor gamma 3
subunit protein.
Length = 449
Score = 50.0 bits (114), Expect = 1e-05
Identities = 37/158 (23%), Positives = 68/158 (43%), Gaps = 7/158 (4%)
Frame = +2
Query: 125 TSLSLMIDSLLATYDRDSPPDSKI---VVNLTLHLRHAN-IRESESTVRIQADLQMNWIG 292
T ++L+++ LL YD+ PD I V+++ +++ + +I W
Sbjct: 27 TDVTLILNKLLREYDKKLRPDIGIKPTVIDVDIYVNSIGPVSSINMEYQIDIFFAQTWTD 86
Query: 293 KRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKR 463
RL +N+ + +W PD + N+ A R+ N+G + + R
Sbjct: 87 SRLRFNSTMKILTLNSNMVGLIWIPDTIFRNSKTAEAHWITTPNQLLRIWNDGKILYTLR 146
Query: 464 LDISTPISMQLDNWPNDMQTCTFKFGSRMHXSDEMDFR 577
L I+ +QL N+P D +C F S + +EM +R
Sbjct: 147 LTINAECQLQLHNFPMDEHSCPLIFSSYGYPKEEMIYR 184
>BC028629-1|AAH28629.1| 492|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 3 protein.
Length = 492
Score = 48.8 bits (111), Expect = 3e-05
Identities = 35/158 (22%), Positives = 69/158 (43%), Gaps = 7/158 (4%)
Frame = +2
Query: 116 ENATSLSLMIDSLLATYDRDSPP---DSKIVVNLTLHLRHAN-IRESESTVRIQADLQMN 283
+N T + ++D LL YD P D+ V +++ + +++ I +
Sbjct: 62 DNITIFTRILDRLLDGYDNRLRPGLGDAVTEVKTDIYVTSFGPVSDTDMEYTIDVFFRQT 121
Query: 284 WIGKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSW 454
W +RL ++ + + ++W PD N + A + R+ +NG++ +
Sbjct: 122 WHDERLKFDGPMKILPLNNLLASKIWTPDTFFHNGKKSVAHNMTTPNKLLRLVDNGTLPY 181
Query: 455 IKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXSDEM 568
RL I M L+++P D+ C KFGS + + E+
Sbjct: 182 TMRLTIHAECPMHLEDFPMDVHACPLKFGSYAYTTAEV 219
>U40583-1|AAA83561.1| 502|Homo sapiens alpha 7 neuronal nicotinic
acetylcholine receptor protein.
Length = 502
Score = 48.4 bits (110), Expect = 3e-05
Identities = 34/137 (24%), Positives = 62/137 (45%), Gaps = 2/137 (1%)
Frame = +2
Query: 173 DSPPDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIGKRLSWNAGEW-GCSTWLVSS 349
DS P + + +L L L+ ++ E + LQM+W L WN E+ G T
Sbjct: 47 DSQPLT-VYFSLNL-LQIMDVDEKNQVLTTNIWLQMSWTDHYLQWNVSEYPGVKTVRFPD 104
Query: 350 ERLWRPDVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTC 526
++W+PD++L N+A + V+ +G ++ + + + +P D+Q C
Sbjct: 105 GQIWKPDILLYNSADERFDATFHTNVLVNPSGHCQYLPPGIFKSSCYIDVRWFPFDVQHC 164
Query: 527 TFKFGSRMHXSDEMDFR 577
KFGS + +D +
Sbjct: 165 KLKFGSWSYGGWSLDLQ 181
>S62908-1|AAB27279.1| 492|Homo sapiens gamma-aminobutyric acidA
receptor alpha 3 subunit protein.
Length = 492
Score = 48.4 bits (110), Expect = 3e-05
Identities = 35/158 (22%), Positives = 69/158 (43%), Gaps = 7/158 (4%)
Frame = +2
Query: 116 ENATSLSLMIDSLLATYDRDSPP---DSKIVVNLTLHLRHAN-IRESESTVRIQADLQMN 283
+N T + ++D LL YD P D+ V +++ + +++ I +
Sbjct: 62 DNITIFTRILDRLLDGYDNRLRPGLGDAVTEVKTDIYVTSFGPVSDTDMEYTIDVFFRQT 121
Query: 284 WIGKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSW 454
W +RL ++ + + ++W PD N + A + R+ +NG++ +
Sbjct: 122 WHDERLKFDGPMKILPLNNLLASKIWTPDTFFHNGKKSVAHNMTTPNKLLRLVDNGTLLY 181
Query: 455 IKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXSDEM 568
RL I M L+++P D+ C KFGS + + E+
Sbjct: 182 TMRLTIHAECPMHLEDFPMDVHACPLKFGSYAYTTAEV 219
>BC111802-1|AAI11803.1| 465|Homo sapiens CHRNG protein protein.
Length = 465
Score = 48.4 bits (110), Expect = 3e-05
Identities = 32/113 (28%), Positives = 54/113 (47%), Gaps = 7/113 (6%)
Frame = +2
Query: 140 MIDSLLATYDRDSPPDSKI--VVNLTLHLRHANI---RESESTVRIQADLQMNWIGKRLS 304
++ L+ YD + P + VVN++L L N+ E E + ++M W RL
Sbjct: 29 LLADLMQNYDPNLRPAERDSDVVNVSLKLTLTNLISLNEREEALTTNVWIEMQWCDYRLR 88
Query: 305 WNAGEW-GCSTWLVSSERLWRPDVVLLNAAAT-TAGDYALRARVSNNGSVSWI 457
W+ ++ G V S +WRPD+VL N + T + + L+ + S+ WI
Sbjct: 89 WDPRDYEGLWVLRVPSTMVWRPDIVLENKSQTYSTNEIDLQLSQEDGQSIEWI 141
>AF385585-1|AAK68111.1| 502|Homo sapiens nicotinic cholinergic
receptor alpha 7 protein.
Length = 502
Score = 48.4 bits (110), Expect = 3e-05
Identities = 34/137 (24%), Positives = 62/137 (45%), Gaps = 2/137 (1%)
Frame = +2
Query: 173 DSPPDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIGKRLSWNAGEW-GCSTWLVSS 349
DS P + + +L L L+ ++ E + LQM+W L WN E+ G T
Sbjct: 47 DSQPLT-VYFSLNL-LQIMDVDEKNQVLTTNIWLQMSWTDHYLQWNVSEYPGVKTVRFPD 104
Query: 350 ERLWRPDVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTC 526
++W+PD++L N+A + V+ +G ++ + + + +P D+Q C
Sbjct: 105 GQIWKPDILLYNSADERFDATFHTNVLVNPSGHCQYLPPGIFKSSCYIDVRWFPFDVQHC 164
Query: 527 TFKFGSRMHXSDEMDFR 577
KFGS + +D +
Sbjct: 165 KLKFGSWSYGGWSLDLQ 181
>AF166361-1|AAG12455.1| 492|Homo sapiens GABA receptor subunit
alpha 3 protein.
Length = 492
Score = 48.4 bits (110), Expect = 3e-05
Identities = 35/158 (22%), Positives = 69/158 (43%), Gaps = 7/158 (4%)
Frame = +2
Query: 116 ENATSLSLMIDSLLATYDRDSPP---DSKIVVNLTLHLRHAN-IRESESTVRIQADLQMN 283
+N T + ++D LL YD P D+ V +++ + +++ I +
Sbjct: 62 DNITIFTRILDRLLDGYDNRLRPGLGDAVTEVKTDIYVTSFGPVSDTDMEYTIDVFFRQT 121
Query: 284 WIGKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSW 454
W +RL ++ + + ++W PD N + A + R+ +NG++ +
Sbjct: 122 WHDERLKFDGPMKILPLNNLLASKIWTPDTFFHNGKKSVAHNMTTPNKLLRLVDNGTLLY 181
Query: 455 IKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXSDEM 568
RL I M L+++P D+ C KFGS + + E+
Sbjct: 182 TMRLTIHAECPMHLEDFPMDVHACPLKFGSYAYTTAEV 219
>AK122638-1|BAC85499.1| 266|Homo sapiens yte protein of 76kDa)
(LCP2). protein.
Length = 266
Score = 48.0 bits (109), Expect = 4e-05
Identities = 25/89 (28%), Positives = 41/89 (46%)
Frame = +2
Query: 272 LQMNWIGKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVS 451
L+++W+ RL+WN + E LW P + +L A D + +ARV +G V
Sbjct: 87 LRLSWLDTRLAWNTSAHPRHAITLPWESLWTPRLTILEALWVDWRDQSPQARVDQDGHVK 146
Query: 452 WIKRLDISTPISMQLDNWPNDMQTCTFKF 538
L T + +L ++P D C+ F
Sbjct: 147 LNLALTTETNCNFELLHFPRDHSNCSLSF 175
>U77731-2|AAB38273.1| 360|Homo sapiens glycine receptor alpha 2B
subunit protein.
Length = 360
Score = 47.2 bits (107), Expect = 8e-05
Identities = 33/135 (24%), Positives = 59/135 (43%), Gaps = 4/135 (2%)
Frame = +2
Query: 182 PDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIGKRLSWNAGEWGCSTWLVSS-ERL 358
P + N+ ++ +I E+ R+ L+ W RL+++ S + +
Sbjct: 69 PPVNVTCNIFIN-SFGSIAETTMDYRVNIFLRQQWNDSRLAYSEYPDDSLDLDPSMLDSI 127
Query: 359 WRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCT 529
W+PD+ N D R+S NG V + RL ++ M L N+P D+QTCT
Sbjct: 128 WKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNFPMDVQTCT 187
Query: 530 FKFGSRMHXSDEMDF 574
+ S + +++ F
Sbjct: 188 MQLESFGYTMNDLIF 202
>CR450343-1|CAG29339.1| 452|Homo sapiens GLRA2 protein.
Length = 452
Score = 47.2 bits (107), Expect = 8e-05
Identities = 33/135 (24%), Positives = 59/135 (43%), Gaps = 4/135 (2%)
Frame = +2
Query: 182 PDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIGKRLSWNAGEWGCSTWLVSS-ERL 358
P + N+ ++ +I E+ R+ L+ W RL+++ S + +
Sbjct: 69 PPVNVTCNIFIN-SFGSIAETTMDYRVNIFLRQQWNDSRLAYSEYPDDSLDLDPSMLDSI 127
Query: 359 WRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCT 529
W+PD+ N D R+S NG V + RL ++ M L N+P D+QTCT
Sbjct: 128 WKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNFPMDVQTCT 187
Query: 530 FKFGSRMHXSDEMDF 574
+ S + +++ F
Sbjct: 188 MQLESFGYTMNDLIF 202
>AY437084-1|AAR87843.1| 452|Homo sapiens glycine receptor alpha2
subunit B protein.
Length = 452
Score = 47.2 bits (107), Expect = 8e-05
Identities = 33/135 (24%), Positives = 59/135 (43%), Gaps = 4/135 (2%)
Frame = +2
Query: 182 PDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIGKRLSWNAGEWGCSTWLVSS-ERL 358
P + N+ ++ +I E+ R+ L+ W RL+++ S + +
Sbjct: 69 PPVNVTCNIFIN-SFGSIAETTMDYRVNIFLRQQWNDSRLAYSEYPDDSLDLDPSMLDSI 127
Query: 359 WRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCT 529
W+PD+ N D R+S NG V + RL ++ M L N+P D+QTCT
Sbjct: 128 WKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNFPMDVQTCT 187
Query: 530 FKFGSRMHXSDEMDF 574
+ S + +++ F
Sbjct: 188 MQLESFGYTMNDLIF 202
>X52008-1|CAA36257.1| 452|Homo sapiens inhibitory glycine receptor
protein.
Length = 452
Score = 46.8 bits (106), Expect = 1e-04
Identities = 32/135 (23%), Positives = 59/135 (43%), Gaps = 4/135 (2%)
Frame = +2
Query: 182 PDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIGKRLSWNAGEWGCSTWLVSS-ERL 358
P + N+ ++ ++ E+ R+ L+ W RL+++ S + +
Sbjct: 69 PPVNVTCNIFIN-SFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPDDSLDLDPSMLDSI 127
Query: 359 WRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCT 529
W+PD+ N D R+S NG V + RL ++ M L N+P D+QTCT
Sbjct: 128 WKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNFPMDVQTCT 187
Query: 530 FKFGSRMHXSDEMDF 574
+ S + +++ F
Sbjct: 188 MQLESFGYTMNDLIF 202
>U77731-1|AAB38272.1| 360|Homo sapiens glycine receptor alpha 2
subunit protein.
Length = 360
Score = 46.8 bits (106), Expect = 1e-04
Identities = 32/135 (23%), Positives = 59/135 (43%), Gaps = 4/135 (2%)
Frame = +2
Query: 182 PDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIGKRLSWNAGEWGCSTWLVSS-ERL 358
P + N+ ++ ++ E+ R+ L+ W RL+++ S + +
Sbjct: 69 PPVNVTCNIFIN-SFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPDDSLDLDPSMLDSI 127
Query: 359 WRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCT 529
W+PD+ N D R+S NG V + RL ++ M L N+P D+QTCT
Sbjct: 128 WKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNFPMDVQTCT 187
Query: 530 FKFGSRMHXSDEMDF 574
+ S + +++ F
Sbjct: 188 MQLESFGYTMNDLIF 202
>S81944-1|AAB36480.1| 453|Homo sapiens gamma-aminobutyric acid type
A receptor alpha 6 subunit protein.
Length = 453
Score = 46.8 bits (106), Expect = 1e-04
Identities = 35/154 (22%), Positives = 64/154 (41%), Gaps = 7/154 (4%)
Frame = +2
Query: 128 SLSLMIDSLLATYDRDSPPD---SKIVVNLTLHLRHAN-IRESESTVRIQADLQMNWIGK 295
++S ++D+LL YD P + V +++ + + E + + W +
Sbjct: 31 NVSRILDNLLEGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTDE 90
Query: 296 RLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRA---RVSNNGSVSWIKRL 466
RL + S + ++W PD N + A + R+ NG++ + RL
Sbjct: 91 RLKFGGPTEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTMRL 150
Query: 467 DISTPISMQLDNWPNDMQTCTFKFGSRMHXSDEM 568
I+ M+L N+P D C KFGS + E+
Sbjct: 151 TINADCPMRLVNFPMDGHACPLKFGSYAYPKSEI 184
>BC099641-1|AAH99641.1| 453|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 6 protein.
Length = 453
Score = 46.8 bits (106), Expect = 1e-04
Identities = 35/154 (22%), Positives = 64/154 (41%), Gaps = 7/154 (4%)
Frame = +2
Query: 128 SLSLMIDSLLATYDRDSPPD---SKIVVNLTLHLRHAN-IRESESTVRIQADLQMNWIGK 295
++S ++D+LL YD P + V +++ + + E + + W +
Sbjct: 31 NVSRILDNLLEGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTDE 90
Query: 296 RLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRA---RVSNNGSVSWIKRL 466
RL + S + ++W PD N + A + R+ NG++ + RL
Sbjct: 91 RLKFGGPTEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTMRL 150
Query: 467 DISTPISMQLDNWPNDMQTCTFKFGSRMHXSDEM 568
I+ M+L N+P D C KFGS + E+
Sbjct: 151 TINADCPMRLVNFPMDGHACPLKFGSYAYPKSEI 184
>BC099640-1|AAH99640.1| 453|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 6 protein.
Length = 453
Score = 46.8 bits (106), Expect = 1e-04
Identities = 35/154 (22%), Positives = 64/154 (41%), Gaps = 7/154 (4%)
Frame = +2
Query: 128 SLSLMIDSLLATYDRDSPPD---SKIVVNLTLHLRHAN-IRESESTVRIQADLQMNWIGK 295
++S ++D+LL YD P + V +++ + + E + + W +
Sbjct: 31 NVSRILDNLLEGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTDE 90
Query: 296 RLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRA---RVSNNGSVSWIKRL 466
RL + S + ++W PD N + A + R+ NG++ + RL
Sbjct: 91 RLKFGGPTEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTMRL 150
Query: 467 DISTPISMQLDNWPNDMQTCTFKFGSRMHXSDEM 568
I+ M+L N+P D C KFGS + E+
Sbjct: 151 TINADCPMRLVNFPMDGHACPLKFGSYAYPKSEI 184
>BC096242-1|AAH96242.1| 453|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 6 protein.
Length = 453
Score = 46.8 bits (106), Expect = 1e-04
Identities = 35/154 (22%), Positives = 64/154 (41%), Gaps = 7/154 (4%)
Frame = +2
Query: 128 SLSLMIDSLLATYDRDSPPD---SKIVVNLTLHLRHAN-IRESESTVRIQADLQMNWIGK 295
++S ++D+LL YD P + V +++ + + E + + W +
Sbjct: 31 NVSRILDNLLEGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTDE 90
Query: 296 RLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRA---RVSNNGSVSWIKRL 466
RL + S + ++W PD N + A + R+ NG++ + RL
Sbjct: 91 RLKFGGPTEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTMRL 150
Query: 467 DISTPISMQLDNWPNDMQTCTFKFGSRMHXSDEM 568
I+ M+L N+P D C KFGS + E+
Sbjct: 151 TINADCPMRLVNFPMDGHACPLKFGSYAYPKSEI 184
>BC096241-1|AAH96241.1| 453|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 6 protein.
Length = 453
Score = 46.8 bits (106), Expect = 1e-04
Identities = 35/154 (22%), Positives = 64/154 (41%), Gaps = 7/154 (4%)
Frame = +2
Query: 128 SLSLMIDSLLATYDRDSPPD---SKIVVNLTLHLRHAN-IRESESTVRIQADLQMNWIGK 295
++S ++D+LL YD P + V +++ + + E + + W +
Sbjct: 31 NVSRILDNLLEGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTDE 90
Query: 296 RLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRA---RVSNNGSVSWIKRL 466
RL + S + ++W PD N + A + R+ NG++ + RL
Sbjct: 91 RLKFGGPTEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTMRL 150
Query: 467 DISTPISMQLDNWPNDMQTCTFKFGSRMHXSDEM 568
I+ M+L N+P D C KFGS + E+
Sbjct: 151 TINADCPMRLVNFPMDGHACPLKFGSYAYPKSEI 184
>BC032864-1|AAH32864.1| 452|Homo sapiens glycine receptor, alpha 2
protein.
Length = 452
Score = 46.8 bits (106), Expect = 1e-04
Identities = 32/135 (23%), Positives = 59/135 (43%), Gaps = 4/135 (2%)
Frame = +2
Query: 182 PDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIGKRLSWNAGEWGCSTWLVSS-ERL 358
P + N+ ++ ++ E+ R+ L+ W RL+++ S + +
Sbjct: 69 PPVNVTCNIFIN-SFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPDDSLDLDPSMLDSI 127
Query: 359 WRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCT 529
W+PD+ N D R+S NG V + RL ++ M L N+P D+QTCT
Sbjct: 128 WKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNFPMDVQTCT 187
Query: 530 FKFGSRMHXSDEMDF 574
+ S + +++ F
Sbjct: 188 MQLESFGYTMNDLIF 202
>AY437083-1|AAR87842.1| 452|Homo sapiens glycine receptor alpha2
subunit A protein.
Length = 452
Score = 46.8 bits (106), Expect = 1e-04
Identities = 32/135 (23%), Positives = 59/135 (43%), Gaps = 4/135 (2%)
Frame = +2
Query: 182 PDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIGKRLSWNAGEWGCSTWLVSS-ERL 358
P + N+ ++ ++ E+ R+ L+ W RL+++ S + +
Sbjct: 69 PPVNVTCNIFIN-SFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPDDSLDLDPSMLDSI 127
Query: 359 WRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCT 529
W+PD+ N D R+S NG V + RL ++ M L N+P D+QTCT
Sbjct: 128 WKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNFPMDVQTCT 187
Query: 530 FKFGSRMHXSDEMDF 574
+ S + +++ F
Sbjct: 188 MQLESFGYTMNDLIF 202
>AJ003080-1|CAA05853.1| 238|Homo sapiens serotonin receptor
protein.
Length = 238
Score = 46.8 bits (106), Expect = 1e-04
Identities = 26/111 (23%), Positives = 48/111 (43%), Gaps = 1/111 (0%)
Frame = +2
Query: 230 NIRESESTVRIQADLQMNWIGKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAG 406
N+ E + + W + L WN ++ T L + ++ +W PD+++
Sbjct: 72 NVDEKNQVLTTYIWYRQYWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKS 131
Query: 407 DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXS 559
+ + G V K L + T S+ + N+P D+Q C+ F S +H S
Sbjct: 132 PNIPYVYIRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLHTS 182
>AF053495-1|AAC35290.1| 452|Homo sapiens glycine receptor alpha 2
subunit protein.
Length = 452
Score = 46.8 bits (106), Expect = 1e-04
Identities = 32/135 (23%), Positives = 59/135 (43%), Gaps = 4/135 (2%)
Frame = +2
Query: 182 PDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIGKRLSWNAGEWGCSTWLVSS-ERL 358
P + N+ ++ ++ E+ R+ L+ W RL+++ S + +
Sbjct: 69 PPVNVTCNIFIN-SFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPDDSLDLDPSMLDSI 127
Query: 359 WRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCT 529
W+PD+ N D R+S NG V + RL ++ M L N+P D+QTCT
Sbjct: 128 WKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNFPMDVQTCT 187
Query: 530 FKFGSRMHXSDEMDF 574
+ S + +++ F
Sbjct: 188 MQLESFGYTMNDLIF 202
>U30461-1|AAB52519.1| 554|Homo sapiens GABAA receptor subunit
alpha4 protein.
Length = 554
Score = 46.4 bits (105), Expect = 1e-04
Identities = 37/151 (24%), Positives = 65/151 (43%), Gaps = 8/151 (5%)
Frame = +2
Query: 140 MIDSLLATYD-RDSP----PDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIGKRLS 304
++DSLL YD R P P +++ ++ + + + E + + WI KRL
Sbjct: 51 ILDSLLDGYDNRLRPGFGGPVTEVKTDIYV-TSFGPVSDVEMEYTMDVFFRQTWIDKRLK 109
Query: 305 WNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRA---RVSNNGSVSWIKRLDIS 475
++ + ++W PD N + + + R+ NG++ + RL IS
Sbjct: 110 YDGPIEILRLNNMMVTKVWTPDTFFRNGKKSVSHNMTAPNKLFRIMRNGTILYTMRLTIS 169
Query: 476 TPISMQLDNWPNDMQTCTFKFGSRMHXSDEM 568
M+L ++P D C KFGS + EM
Sbjct: 170 AECPMRLVDFPMDGHACPLKFGSYAYPKSEM 200
>S82612-1|AAB37533.2| 478|Homo sapiens 5-hydroxytryptamine type 3AS
receptor subunit protein.
Length = 478
Score = 46.4 bits (105), Expect = 1e-04
Identities = 25/115 (21%), Positives = 50/115 (43%), Gaps = 1/115 (0%)
Frame = +2
Query: 230 NIRESESTVRIQADLQMNWIGKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAG 406
N+ E + + W + L WN ++ T L + ++ +W PD+++
Sbjct: 72 NVDEKNQVLTTYIWYRQYWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINELVDVGKS 131
Query: 407 DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXSDEMD 571
+ + G V K L + T S+ + N+P D+Q C+ F S +H +++
Sbjct: 132 PNIPYVYIRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLHTIQDIN 186
>BC035055-1|AAH35055.1| 554|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 4 protein.
Length = 554
Score = 46.4 bits (105), Expect = 1e-04
Identities = 37/151 (24%), Positives = 65/151 (43%), Gaps = 8/151 (5%)
Frame = +2
Query: 140 MIDSLLATYD-RDSP----PDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIGKRLS 304
++DSLL YD R P P +++ ++ + + + E + + WI KRL
Sbjct: 51 ILDSLLDGYDNRLRPGFGGPVTEVKTDIYV-TSFGPVSDVEMEYTMDVFFRQTWIDKRLK 109
Query: 305 WNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRA---RVSNNGSVSWIKRLDIS 475
++ + ++W PD N + + + R+ NG++ + RL IS
Sbjct: 110 YDGPIEILRLNNMMVTKVWTPDTFFRNGKKSVSHNMTAPNKLFRIMRNGTILYTMRLTIS 169
Query: 476 TPISMQLDNWPNDMQTCTFKFGSRMHXSDEM 568
M+L ++P D C KFGS + EM
Sbjct: 170 AECPMRLVDFPMDGHACPLKFGSYAYPKSEM 200
>D49394-1|BAA08387.1| 478|Homo sapiens serotonin 5-HT3 receptor
protein.
Length = 478
Score = 46.0 bits (104), Expect = 2e-04
Identities = 25/115 (21%), Positives = 50/115 (43%), Gaps = 1/115 (0%)
Frame = +2
Query: 230 NIRESESTVRIQADLQMNWIGKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAG 406
N+ E + + W + L WN ++ T L + ++ +W PD+++
Sbjct: 72 NVDEKNQVLTTYIWYRQYWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKS 131
Query: 407 DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXSDEMD 571
+ + G V K L + T S+ + N+P D+Q C+ F S +H +++
Sbjct: 132 PNIPYVYIRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLHTIQDIN 186
>BT007204-1|AAP35868.1| 484|Homo sapiens 5-hydroxytryptamine
(serotonin) receptor 3A protein.
Length = 484
Score = 46.0 bits (104), Expect = 2e-04
Identities = 25/115 (21%), Positives = 50/115 (43%), Gaps = 1/115 (0%)
Frame = +2
Query: 230 NIRESESTVRIQADLQMNWIGKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAG 406
N+ E + + W + L WN ++ T L + ++ +W PD+++
Sbjct: 78 NVDEKNQVLTTYIWYRQYWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKS 137
Query: 407 DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXSDEMD 571
+ + G V K L + T S+ + N+P D+Q C+ F S +H +++
Sbjct: 138 PNIPYVYIRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLHTIQDIN 192
>BC004453-1|AAH04453.2| 478|Homo sapiens 5-hydroxytryptamine
(serotonin) receptor 3A protein.
Length = 478
Score = 46.0 bits (104), Expect = 2e-04
Identities = 25/115 (21%), Positives = 50/115 (43%), Gaps = 1/115 (0%)
Frame = +2
Query: 230 NIRESESTVRIQADLQMNWIGKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAG 406
N+ E + + W + L WN ++ T L + ++ +W PD+++
Sbjct: 72 NVDEKNQVLTTYIWYRQYWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKS 131
Query: 407 DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXSDEMD 571
+ + G V K L + T S+ + N+P D+Q C+ F S +H +++
Sbjct: 132 PNIPYVYIRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLHTIQDIN 186
>BC002354-1|AAH02354.1| 478|Homo sapiens 5-hydroxytryptamine
(serotonin) receptor 3A protein.
Length = 478
Score = 46.0 bits (104), Expect = 2e-04
Identities = 25/115 (21%), Positives = 50/115 (43%), Gaps = 1/115 (0%)
Frame = +2
Query: 230 NIRESESTVRIQADLQMNWIGKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAG 406
N+ E + + W + L WN ++ T L + ++ +W PD+++
Sbjct: 72 NVDEKNQVLTTYIWYRQYWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKS 131
Query: 407 DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXSDEMD 571
+ + G V K L + T S+ + N+P D+Q C+ F S +H +++
Sbjct: 132 PNIPYVYIRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLHTIQDIN 186
>AJ005205-1|CAA06442.3| 478|Homo sapiens serotonin 3 receptor
protein.
Length = 478
Score = 46.0 bits (104), Expect = 2e-04
Identities = 25/115 (21%), Positives = 50/115 (43%), Gaps = 1/115 (0%)
Frame = +2
Query: 230 NIRESESTVRIQADLQMNWIGKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAG 406
N+ E + + W + L WN ++ T L + ++ +W PD+++
Sbjct: 72 NVDEKNQVLTTYIWYRQYWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKS 131
Query: 407 DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXSDEMD 571
+ + G V K L + T S+ + N+P D+Q C+ F S +H +++
Sbjct: 132 PNIPYVYIRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLHTIQDIN 186
>AJ003079-1|CAA05852.1| 478|Homo sapiens 5-hydroxytryptamine3
receptor protein.
Length = 478
Score = 46.0 bits (104), Expect = 2e-04
Identities = 25/115 (21%), Positives = 50/115 (43%), Gaps = 1/115 (0%)
Frame = +2
Query: 230 NIRESESTVRIQADLQMNWIGKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAG 406
N+ E + + W + L WN ++ T L + ++ +W PD+++
Sbjct: 72 NVDEKNQVLTTYIWYRQYWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKS 131
Query: 407 DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXSDEMD 571
+ + G V K L + T S+ + N+P D+Q C+ F S +H +++
Sbjct: 132 PNIPYVYIRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLHTIQDIN 186
>AJ003078-1|CAA05851.1| 510|Homo sapiens serotonin receptor
protein.
Length = 510
Score = 46.0 bits (104), Expect = 2e-04
Identities = 25/115 (21%), Positives = 50/115 (43%), Gaps = 1/115 (0%)
Frame = +2
Query: 230 NIRESESTVRIQADLQMNWIGKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAG 406
N+ E + + W + L WN ++ T L + ++ +W PD+++
Sbjct: 72 NVDEKNQVLTTYIWYRQYWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKS 131
Query: 407 DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXSDEMD 571
+ + G V K L + T S+ + N+P D+Q C+ F S +H +++
Sbjct: 132 PNIPYVYIRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLHTIQDIN 186
>AF498984-1|AAM21131.1| 478|Homo sapiens 5-hydroxytryptamine
receptor 3A protein.
Length = 478
Score = 46.0 bits (104), Expect = 2e-04
Identities = 25/115 (21%), Positives = 50/115 (43%), Gaps = 1/115 (0%)
Frame = +2
Query: 230 NIRESESTVRIQADLQMNWIGKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAG 406
N+ E + + W + L WN ++ T L + ++ +W PD+++
Sbjct: 72 NVDEKNQVLTTYIWYRQYWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKS 131
Query: 407 DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXSDEMD 571
+ + G V K L + T S+ + N+P D+Q C+ F S +H +++
Sbjct: 132 PNIPYVYIRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLHTIQDIN 186
>BC096083-1|AAH96083.1| 198|Homo sapiens CHRNB4 protein protein.
Length = 198
Score = 44.8 bits (101), Expect = 4e-04
Identities = 29/115 (25%), Positives = 54/115 (46%), Gaps = 8/115 (6%)
Frame = +2
Query: 92 AIASAAECENATSLSLMIDSLL--ATYD---RDSPPDSKIV-VNLTLHLRHA-NIRESES 250
A+ C A + ++D LL Y+ R + S+++ + L L L ++ E E
Sbjct: 14 ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQ 73
Query: 251 TVRIQADLQMNWIGKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDY 412
+ L+ W RL+WN+ + G + + ++R+W PD+VL N + T +
Sbjct: 74 IMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNKSLRTGSTW 128
>BC096081-1|AAH96081.1| 198|Homo sapiens CHRNB4 protein protein.
Length = 198
Score = 44.8 bits (101), Expect = 4e-04
Identities = 29/115 (25%), Positives = 54/115 (46%), Gaps = 8/115 (6%)
Frame = +2
Query: 92 AIASAAECENATSLSLMIDSLL--ATYD---RDSPPDSKIV-VNLTLHLRHA-NIRESES 250
A+ C A + ++D LL Y+ R + S+++ + L L L ++ E E
Sbjct: 14 ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQ 73
Query: 251 TVRIQADLQMNWIGKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDY 412
+ L+ W RL+WN+ + G + + ++R+W PD+VL N + T +
Sbjct: 74 IMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNKSLRTGSTW 128
>BC033801-1|AAH33801.1| 452|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, delta protein.
Length = 452
Score = 43.6 bits (98), Expect = 0.001
Identities = 37/149 (24%), Positives = 63/149 (42%), Gaps = 7/149 (4%)
Frame = +2
Query: 143 IDSLLATYDRDSPPD-SKIVVNLTLHLRHANI---RESESTVRIQADLQMNWIGKRLSWN 310
+D L+A Y R+ P VN+ L L A+I E+ + L +W RLS+N
Sbjct: 44 LDGLIAGYARNFRPGIGGPPVNVALALEVASIDHISEANMEYTMTVFLHQSWRDSRLSYN 103
Query: 311 AGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTP 481
++LW PD ++NA + D + R+ +G + + R+ +
Sbjct: 104 HTNETLGLDSRFVDKLWLPDTFIVNAKSAWFHDVTVENKLIRLQPDGVILYSIRITSTVA 163
Query: 482 ISMQLDNWPNDMQTCTFKFGSRMHXSDEM 568
M L +P D Q C S + S+++
Sbjct: 164 CDMDLAKYPMDEQECMLDLESYGYSSEDI 192
>AL391845-4|CAI15436.1| 452|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, delta protein.
Length = 452
Score = 43.6 bits (98), Expect = 0.001
Identities = 37/149 (24%), Positives = 63/149 (42%), Gaps = 7/149 (4%)
Frame = +2
Query: 143 IDSLLATYDRDSPPD-SKIVVNLTLHLRHANI---RESESTVRIQADLQMNWIGKRLSWN 310
+D L+A Y R+ P VN+ L L A+I E+ + L +W RLS+N
Sbjct: 44 LDGLIAGYARNFRPGIGGPPVNVALALEVASIDHISEANMEYTMTVFLHQSWRDSRLSYN 103
Query: 311 AGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTP 481
++LW PD ++NA + D + R+ +G + + R+ +
Sbjct: 104 HTNETLGLDSRFVDKLWLPDTFIVNAKSAWFHDVTVENKLIRLQPDGVILYSIRITSTVA 163
Query: 482 ISMQLDNWPNDMQTCTFKFGSRMHXSDEM 568
M L +P D Q C S + S+++
Sbjct: 164 CDMDLAKYPMDEQECMLDLESYGYSSEDI 192
>AF016917-1|AAB70007.1| 452|Homo sapiens GABA-A receptor delta
subunit protein.
Length = 452
Score = 43.6 bits (98), Expect = 0.001
Identities = 37/149 (24%), Positives = 63/149 (42%), Gaps = 7/149 (4%)
Frame = +2
Query: 143 IDSLLATYDRDSPPD-SKIVVNLTLHLRHANI---RESESTVRIQADLQMNWIGKRLSWN 310
+D L+A Y R+ P VN+ L L A+I E+ + L +W RLS+N
Sbjct: 44 LDGLIAGYARNFRPGIGGPPVNVALALEVASIDHISEANMEYTMTVFLHQSWRDSRLSYN 103
Query: 311 AGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTP 481
++LW PD ++NA + D + R+ +G + + R+ +
Sbjct: 104 HTNETLGLDSRFVDKLWLPDTFIVNAKSAWFHDVTVENKLIRLQPDGVILYSIRITSTVA 163
Query: 482 ISMQLDNWPNDMQTCTFKFGSRMHXSDEM 568
M L +P D Q C S + S+++
Sbjct: 164 CDMDLAKYPMDEQECMLDLESYGYSSEDI 192
>U95367-1|AAC51357.1| 440|Homo sapiens GABA-A receptor pi subunit
protein.
Length = 440
Score = 43.2 bits (97), Expect = 0.001
Identities = 39/164 (23%), Positives = 76/164 (46%), Gaps = 9/164 (5%)
Frame = +2
Query: 110 ECENATSLSLM-IDSLLATYDRDSPPD---SKIVVNLTLHLRH-ANIRESESTVRIQADL 274
E + LSL ++L A Y++ P+ + + LTL + ++I ES L
Sbjct: 29 EVGRSDKLSLPGFENLTAGYNKFLRPNFGGEPVQIALTLDIASISSISESNMDYTATIYL 88
Query: 275 QMNWIGKRLSWNAGE-WGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNG 442
+ W+ +RL + + + LV E LW PD ++ + + + + R+ +NG
Sbjct: 89 RQRWMDQRLVFEGNKSFTLDARLV--EFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNG 146
Query: 443 SVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXSDEMDF 574
+V + R+ + +M L +P D QTC + S + ++++F
Sbjct: 147 TVLYALRITTTVACNMDLSKYPMDTQTCKLQLESWGYDGNDVEF 190
>BC109211-1|AAI09212.1| 632|Homo sapiens gamma-aminobutyric acid
(GABA) receptor, theta protein.
Length = 632
Score = 43.2 bits (97), Expect = 0.001
Identities = 34/145 (23%), Positives = 59/145 (40%), Gaps = 7/145 (4%)
Frame = +2
Query: 113 CENATSLSLMIDSLLATYDRDSPPD---SKIVVNLTLHLRHAN-IRESESTVRIQADLQM 280
C N + ++D +L+ YD P+ + + V +++++ I E I
Sbjct: 53 CANEAVVQKILDRVLSRYDVRLRPNFGGAPVPVRISIYVTSIEQISEMNMDYTITMFFHQ 112
Query: 281 NWIGKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSN---NGSVS 451
W RL++ + E+LW PD LN+ D + RV +G+V
Sbjct: 113 TWKDSRLAYYETTLNLTLDYRMHEKLWVPDCYFLNSKDAFVHDVTVENRVFQLHPDGTVR 172
Query: 452 WIKRLDISTPISMQLDNWPNDMQTC 526
+ RL + S+ L +P D Q C
Sbjct: 173 YGIRLTTTAACSLDLHKFPMDKQAC 197
>BC109210-1|AAI09211.1| 632|Homo sapiens gamma-aminobutyric acid
(GABA) receptor, theta protein.
Length = 632
Score = 43.2 bits (97), Expect = 0.001
Identities = 34/145 (23%), Positives = 59/145 (40%), Gaps = 7/145 (4%)
Frame = +2
Query: 113 CENATSLSLMIDSLLATYDRDSPPD---SKIVVNLTLHLRHAN-IRESESTVRIQADLQM 280
C N + ++D +L+ YD P+ + + V +++++ I E I
Sbjct: 53 CANEAVVQKILDRVLSRYDVRLRPNFGGAPVPVRISIYVTSIEQISEMNMDYTITMFFHQ 112
Query: 281 NWIGKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSN---NGSVS 451
W RL++ + E+LW PD LN+ D + RV +G+V
Sbjct: 113 TWKDSRLAYYETTLNLTLDYRMHEKLWVPDCYFLNSKDAFVHDVTVENRVFQLHPDGTVR 172
Query: 452 WIKRLDISTPISMQLDNWPNDMQTC 526
+ RL + S+ L +P D Q C
Sbjct: 173 YGIRLTTTAACSLDLHKFPMDKQAC 197
>BC109106-1|AAI09107.1| 440|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, pi protein.
Length = 440
Score = 43.2 bits (97), Expect = 0.001
Identities = 39/164 (23%), Positives = 76/164 (46%), Gaps = 9/164 (5%)
Frame = +2
Query: 110 ECENATSLSLM-IDSLLATYDRDSPPD---SKIVVNLTLHLRH-ANIRESESTVRIQADL 274
E + LSL ++L A Y++ P+ + + LTL + ++I ES L
Sbjct: 29 EVGRSDKLSLPGFENLTAGYNKFLRPNFGGEPVQIALTLDIASISSISESNMDYTATIYL 88
Query: 275 QMNWIGKRLSWNAGE-WGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNG 442
+ W+ +RL + + + LV E LW PD ++ + + + + R+ +NG
Sbjct: 89 RQRWMDQRLVFEGNKSFTLDARLV--EFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNG 146
Query: 443 SVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXSDEMDF 574
+V + R+ + +M L +P D QTC + S + ++++F
Sbjct: 147 TVLYALRITTTVACNMDLSKYPMDTQTCKLQLESWGYDGNDVEF 190
>BC109105-1|AAI09106.1| 440|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, pi protein.
Length = 440
Score = 43.2 bits (97), Expect = 0.001
Identities = 39/164 (23%), Positives = 76/164 (46%), Gaps = 9/164 (5%)
Frame = +2
Query: 110 ECENATSLSLM-IDSLLATYDRDSPPD---SKIVVNLTLHLRH-ANIRESESTVRIQADL 274
E + LSL ++L A Y++ P+ + + LTL + ++I ES L
Sbjct: 29 EVGRSDKLSLPGFENLTAGYNKFLRPNFGGEPVQIALTLDIASISSISESNMDYTATIYL 88
Query: 275 QMNWIGKRLSWNAGE-WGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNG 442
+ W+ +RL + + + LV E LW PD ++ + + + + R+ +NG
Sbjct: 89 RQRWMDQRLVFEGNKSFTLDARLV--EFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNG 146
Query: 443 SVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXSDEMDF 574
+V + R+ + +M L +P D QTC + S + ++++F
Sbjct: 147 TVLYALRITTTVACNMDLSKYPMDTQTCKLQLESWGYDGNDVEF 190
>BC074865-1|AAH74865.1| 440|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, pi protein.
Length = 440
Score = 43.2 bits (97), Expect = 0.001
Identities = 39/164 (23%), Positives = 76/164 (46%), Gaps = 9/164 (5%)
Frame = +2
Query: 110 ECENATSLSLM-IDSLLATYDRDSPPD---SKIVVNLTLHLRH-ANIRESESTVRIQADL 274
E + LSL ++L A Y++ P+ + + LTL + ++I ES L
Sbjct: 29 EVGRSDKLSLPGFENLTAGYNKFLRPNFGGEPVQIALTLDIASISSISESNMDYTATIYL 88
Query: 275 QMNWIGKRLSWNAGE-WGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNG 442
+ W+ +RL + + + LV E LW PD ++ + + + + R+ +NG
Sbjct: 89 RQRWMDQRLVFEGNKSFTLDARLV--EFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNG 146
Query: 443 SVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXSDEMDF 574
+V + R+ + +M L +P D QTC + S + ++++F
Sbjct: 147 TVLYALRITTTVACNMDLSKYPMDTQTCKLQLESWGYDGNDVEF 190
>BC074810-1|AAH74810.1| 440|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, pi protein.
Length = 440
Score = 43.2 bits (97), Expect = 0.001
Identities = 39/164 (23%), Positives = 76/164 (46%), Gaps = 9/164 (5%)
Frame = +2
Query: 110 ECENATSLSLM-IDSLLATYDRDSPPD---SKIVVNLTLHLRH-ANIRESESTVRIQADL 274
E + LSL ++L A Y++ P+ + + LTL + ++I ES L
Sbjct: 29 EVGRSDKLSLPGFENLTAGYNKFLRPNFGGEPVQIALTLDIASISSISESNMDYTATIYL 88
Query: 275 QMNWIGKRLSWNAGE-WGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNG 442
+ W+ +RL + + + LV E LW PD ++ + + + + R+ +NG
Sbjct: 89 RQRWMDQRLVFEGNKSFTLDARLV--EFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNG 146
Query: 443 SVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXSDEMDF 574
+V + R+ + +M L +P D QTC + S + ++++F
Sbjct: 147 TVLYALRITTTVACNMDLSKYPMDTQTCKLQLESWGYDGNDVEF 190
>AF189259-1|AAF70380.1| 632|Homo sapiens GABA-A receptor theta
subunit protein.
Length = 632
Score = 43.2 bits (97), Expect = 0.001
Identities = 34/145 (23%), Positives = 59/145 (40%), Gaps = 7/145 (4%)
Frame = +2
Query: 113 CENATSLSLMIDSLLATYDRDSPPD---SKIVVNLTLHLRHAN-IRESESTVRIQADLQM 280
C N + ++D +L+ YD P+ + + V +++++ I E I
Sbjct: 53 CANEAVVQKILDRVLSRYDVRLRPNFGGAPVPVRISIYVTSIEQISEMNMDYTITMFFHQ 112
Query: 281 NWIGKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSN---NGSVS 451
W RL++ + E+LW PD LN+ D + RV +G+V
Sbjct: 113 TWKDSRLAYYETTLNLTLDYRMHEKLWVPDCYFLNSKDAFVHDVTVENRVFQLHPDGTVR 172
Query: 452 WIKRLDISTPISMQLDNWPNDMQTC 526
+ RL + S+ L +P D Q C
Sbjct: 173 YGIRLTTTAACSLDLHKFPMDKQAC 197
>AF144648-1|AAD51172.1| 627|Homo sapiens GABA-A receptor theta
protein.
Length = 627
Score = 43.2 bits (97), Expect = 0.001
Identities = 34/145 (23%), Positives = 59/145 (40%), Gaps = 7/145 (4%)
Frame = +2
Query: 113 CENATSLSLMIDSLLATYDRDSPPD---SKIVVNLTLHLRHAN-IRESESTVRIQADLQM 280
C N + ++D +L+ YD P+ + + V +++++ I E I
Sbjct: 48 CANEAVVQKILDRVLSRYDVRLRPNFGGAPVPVRISIYVTSIEQISEMNMDYTITMFFHQ 107
Query: 281 NWIGKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSN---NGSVS 451
W RL++ + E+LW PD LN+ D + RV +G+V
Sbjct: 108 TWKDSRLAYYETTLNLTLDYRMHEKLWVPDCYFLNSKDAFVHDVTVENRVFQLHPDGTVR 167
Query: 452 WIKRLDISTPISMQLDNWPNDMQTC 526
+ RL + S+ L +P D Q C
Sbjct: 168 YGIRLTTTAACSLDLHKFPMDKQAC 192
>AF009702-1|AAC24194.1| 440|Homo sapiens GABA-A receptor pi subunit
protein.
Length = 440
Score = 43.2 bits (97), Expect = 0.001
Identities = 39/164 (23%), Positives = 76/164 (46%), Gaps = 9/164 (5%)
Frame = +2
Query: 110 ECENATSLSLM-IDSLLATYDRDSPPD---SKIVVNLTLHLRH-ANIRESESTVRIQADL 274
E + LSL ++L A Y++ P+ + + LTL + ++I ES L
Sbjct: 29 EVGRSDKLSLPGFENLTAGYNKFLRPNFGGEPVQIALTLDIASISSISESNMDYTATIYL 88
Query: 275 QMNWIGKRLSWNAGE-WGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNG 442
+ W+ +RL + + + LV E LW PD ++ + + + + R+ +NG
Sbjct: 89 RQRWMDQRLVFEGNKSFTLDARLV--EFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNG 146
Query: 443 SVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXSDEMDF 574
+V + R+ + +M L +P D QTC + S + ++++F
Sbjct: 147 TVLYALRITTTVACNMDLSKYPMDTQTCKLQLESWGYDGNDVEF 190
>X52009-1|CAA36258.1| 449|Homo sapiens inhibitory glycine receptor
protein.
Length = 449
Score = 42.7 bits (96), Expect = 0.002
Identities = 29/119 (24%), Positives = 53/119 (44%), Gaps = 4/119 (3%)
Frame = +2
Query: 230 NIRESESTVRIQADLQMNWIGKRLSWNAGEWGCSTWLVSS-ERLWRPDVVLLNAAATTAG 406
+I E+ R+ L+ W RL++N S + +W+PD+ N
Sbjct: 78 SIAETTMDYRVNIFLRQQWNDPRLAYNEYPDDSLDLDPSMLDSIWKPDLFFANEKGAHFH 137
Query: 407 DYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXSDEMDF 574
+ R+S NG+V + R+ ++ M L N+P D+QTC + S + +++ F
Sbjct: 138 EITTDNKLLRISRNGNVLYSIRITLTLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIF 196
>BC114947-1|AAI14948.1| 457|Homo sapiens GLRA1 protein protein.
Length = 457
Score = 42.7 bits (96), Expect = 0.002
Identities = 29/119 (24%), Positives = 53/119 (44%), Gaps = 4/119 (3%)
Frame = +2
Query: 230 NIRESESTVRIQADLQMNWIGKRLSWNAGEWGCSTWLVSS-ERLWRPDVVLLNAAATTAG 406
+I E+ R+ L+ W RL++N S + +W+PD+ N
Sbjct: 78 SIAETTMDYRVNIFLRQQWNDPRLAYNEYPDDSLDLDPSMLDSIWKPDLFFANEKGAHFH 137
Query: 407 DYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXSDEMDF 574
+ R+S NG+V + R+ ++ M L N+P D+QTC + S + +++ F
Sbjct: 138 EITTDNKLLRISRNGNVLYSIRITLTLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIF 196
>BC074980-1|AAH74980.1| 449|Homo sapiens glycine receptor, alpha 1
(startle disease/hyperekplexia) protein.
Length = 449
Score = 42.7 bits (96), Expect = 0.002
Identities = 29/119 (24%), Positives = 53/119 (44%), Gaps = 4/119 (3%)
Frame = +2
Query: 230 NIRESESTVRIQADLQMNWIGKRLSWNAGEWGCSTWLVSS-ERLWRPDVVLLNAAATTAG 406
+I E+ R+ L+ W RL++N S + +W+PD+ N
Sbjct: 78 SIAETTMDYRVNIFLRQQWNDPRLAYNEYPDDSLDLDPSMLDSIWKPDLFFANEKGAHFH 137
Query: 407 DYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXSDEMDF 574
+ R+S NG+V + R+ ++ M L N+P D+QTC + S + +++ F
Sbjct: 138 EITTDNKLLRISRNGNVLYSIRITLTLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIF 196
>BC031087-1|AAH31087.1| 465|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, gamma 1 protein.
Length = 465
Score = 42.7 bits (96), Expect = 0.002
Identities = 34/156 (21%), Positives = 65/156 (41%), Gaps = 7/156 (4%)
Frame = +2
Query: 131 LSLMIDSLLATYDRDSPPDSKI---VVNLTLHLRHAN-IRESESTVRIQADLQMNWIGKR 298
++ +++SLL YD PD + V+ +++ + I W R
Sbjct: 64 ITQILNSLLQGYDNKLRPDIGVRPTVIETDVYVNSIGPVDPINMEYTIDIIFAQTWFDSR 123
Query: 299 LSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLD 469
L +N+ ++W PD N+ + A R+ N+G V + RL
Sbjct: 124 LKFNSTMKVLMLNSNMVGKIWIPDTFFRNSRKSDAHWITTPNRLLRIWNDGRVLYTLRLT 183
Query: 470 ISTPISMQLDNWPNDMQTCTFKFGSRMHXSDEMDFR 577
I+ +QL N+P D +C +F S + +E++++
Sbjct: 184 INAECYLQLHNFPMDEHSCPLEFSSYGYPKNEIEYK 219
>BC074795-1|AAH74795.1| 467|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, gamma 2 protein.
Length = 467
Score = 41.5 bits (93), Expect = 0.004
Identities = 33/156 (21%), Positives = 66/156 (42%), Gaps = 7/156 (4%)
Frame = +2
Query: 131 LSLMIDSLLATYDRDSPPDSKIVVNLTLHLRHANIRESESTVRIQADLQM----NWIGKR 298
+++++++LL YD PD + L + N + + ++ + + W +R
Sbjct: 66 VTVILNNLLEGYDNKLRPDIGVKPTLIHTDMYVNSIGPVNAINMEYTIDIFFAQTWYDRR 125
Query: 299 LSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYAL---RARVSNNGSVSWIKRLD 469
L +N+ ++W PD N+ A R+ N+G V + RL
Sbjct: 126 LKFNSTIKVLRLNSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYTLRLT 185
Query: 470 ISTPISMQLDNWPNDMQTCTFKFGSRMHXSDEMDFR 577
I +QL N+P D +C +F S + +E+ ++
Sbjct: 186 IDAECQLQLHNFPMDEHSCPLEFSSYGYPREEIVYQ 221
>BC069348-1|AAH69348.1| 467|Homo sapiens gamma-aminobutyric acid A
receptor, gamma 2, isoform 2 precursor protein.
Length = 467
Score = 41.5 bits (93), Expect = 0.004
Identities = 33/156 (21%), Positives = 66/156 (42%), Gaps = 7/156 (4%)
Frame = +2
Query: 131 LSLMIDSLLATYDRDSPPDSKIVVNLTLHLRHANIRESESTVRIQADLQM----NWIGKR 298
+++++++LL YD PD + L + N + + ++ + + W +R
Sbjct: 66 VTVILNNLLEGYDNKLRPDIGVKPTLIHTDMYVNSIGPVNAINMEYTIDIFFAQTWYDRR 125
Query: 299 LSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYAL---RARVSNNGSVSWIKRLD 469
L +N+ ++W PD N+ A R+ N+G V + RL
Sbjct: 126 LKFNSTIKVLRLNSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYTLRLT 185
Query: 470 ISTPISMQLDNWPNDMQTCTFKFGSRMHXSDEMDFR 577
I +QL N+P D +C +F S + +E+ ++
Sbjct: 186 IDAECQLQLHNFPMDEHSCPLEFSSYGYPREEIVYQ 221
>BC059389-1|AAH59389.1| 475|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, gamma 2 protein.
Length = 475
Score = 41.5 bits (93), Expect = 0.004
Identities = 33/156 (21%), Positives = 66/156 (42%), Gaps = 7/156 (4%)
Frame = +2
Query: 131 LSLMIDSLLATYDRDSPPDSKIVVNLTLHLRHANIRESESTVRIQADLQM----NWIGKR 298
+++++++LL YD PD + L + N + + ++ + + W +R
Sbjct: 66 VTVILNNLLEGYDNKLRPDIGVKPTLIHTDMYVNSIGPVNAINMEYTIDIFFAQTWYDRR 125
Query: 299 LSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYAL---RARVSNNGSVSWIKRLD 469
L +N+ ++W PD N+ A R+ N+G V + RL
Sbjct: 126 LKFNSTIKVLRLNSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYTLRLT 185
Query: 470 ISTPISMQLDNWPNDMQTCTFKFGSRMHXSDEMDFR 577
I +QL N+P D +C +F S + +E+ ++
Sbjct: 186 IDAECQLQLHNFPMDEHSCPLEFSSYGYPREEIVYQ 221
>AF165124-1|AAD50273.1| 467|Homo sapiens gamma-aminobutyric acid A
receptor gamma 2 protein.
Length = 467
Score = 41.5 bits (93), Expect = 0.004
Identities = 33/156 (21%), Positives = 66/156 (42%), Gaps = 7/156 (4%)
Frame = +2
Query: 131 LSLMIDSLLATYDRDSPPDSKIVVNLTLHLRHANIRESESTVRIQADLQM----NWIGKR 298
+++++++LL YD PD + L + N + + ++ + + W +R
Sbjct: 66 VTVILNNLLEGYDNKLRPDIGVKPTLIHTDMYVNSIGPVNAINMEYTIDIFFAQTWYDRR 125
Query: 299 LSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYAL---RARVSNNGSVSWIKRLD 469
L +N+ ++W PD N+ A R+ N+G V + RL
Sbjct: 126 LKFNSTIKVLRLNSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYTLRLT 185
Query: 470 ISTPISMQLDNWPNDMQTCTFKFGSRMHXSDEMDFR 577
I +QL N+P D +C +F S + +E+ ++
Sbjct: 186 IDAECQLQLHNFPMDEHSCPLEFSSYGYPREEIVYQ 221
>Z93848-1|CAI41994.1| 376|Homo sapiens glycine receptor, alpha 4
protein.
Length = 376
Score = 40.7 bits (91), Expect = 0.007
Identities = 30/125 (24%), Positives = 53/125 (42%), Gaps = 4/125 (3%)
Frame = +2
Query: 182 PDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIGKRLSWNAGEWGCSTWLVSS-ERL 358
P + N+ ++ ++I ++ R+ L+ W RLS+ S + +
Sbjct: 28 PPVNVTCNIFIN-SFSSITKTTMDYRVNVFLRQQWNDPRLSYREYPDDSLDLDPSMLDSI 86
Query: 359 WRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCT 529
W+PD+ N + R+ NG+V + RL + M L N+P D+QTCT
Sbjct: 87 WKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLILSCLMDLKNFPMDIQTCT 146
Query: 530 FKFGS 544
+ S
Sbjct: 147 MQLES 151
>U93917-1|AAC39917.1| 449|Homo sapiens glycine receptor alpha 3
subunit protein.
Length = 449
Score = 40.7 bits (91), Expect = 0.007
Identities = 30/135 (22%), Positives = 58/135 (42%), Gaps = 4/135 (2%)
Frame = +2
Query: 182 PDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIGKRLSWNAGEWGCSTWLVSS-ERL 358
P + N+ ++ +I E+ R+ L+ W RL+++ S + +
Sbjct: 68 PPVNVTCNIFIN-SFGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPDDSLDLDPSMLDSI 126
Query: 359 WRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCT 529
W+PD+ N + R+ NG+V + RL ++ M L N+P D+QTC
Sbjct: 127 WKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFPMDVQTCI 186
Query: 530 FKFGSRMHXSDEMDF 574
+ S + +++ F
Sbjct: 187 MQLESFGYTMNDLIF 201
>BC036086-1|AAH36086.1| 464|Homo sapiens glycine receptor, alpha 3
protein.
Length = 464
Score = 40.7 bits (91), Expect = 0.007
Identities = 30/135 (22%), Positives = 58/135 (42%), Gaps = 4/135 (2%)
Frame = +2
Query: 182 PDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIGKRLSWNAGEWGCSTWLVSS-ERL 358
P + N+ ++ +I E+ R+ L+ W RL+++ S + +
Sbjct: 68 PPVNVTCNIFIN-SFGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPDDSLDLDPSMLDSI 126
Query: 359 WRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCT 529
W+PD+ N + R+ NG+V + RL ++ M L N+P D+QTC
Sbjct: 127 WKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFPMDVQTCI 186
Query: 530 FKFGSRMHXSDEMDF 574
+ S + +++ F
Sbjct: 187 MQLESFGYTMNDLIF 201
>AL049610-1|CAI42158.1| 376|Homo sapiens glycine receptor, alpha 4
protein.
Length = 376
Score = 40.7 bits (91), Expect = 0.007
Identities = 30/125 (24%), Positives = 53/125 (42%), Gaps = 4/125 (3%)
Frame = +2
Query: 182 PDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIGKRLSWNAGEWGCSTWLVSS-ERL 358
P + N+ ++ ++I ++ R+ L+ W RLS+ S + +
Sbjct: 28 PPVNVTCNIFIN-SFSSITKTTMDYRVNVFLRQQWNDPRLSYREYPDDSLDLDPSMLDSI 86
Query: 359 WRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCT 529
W+PD+ N + R+ NG+V + RL + M L N+P D+QTCT
Sbjct: 87 WKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLILSCLMDLKNFPMDIQTCT 146
Query: 530 FKFGS 544
+ S
Sbjct: 147 MQLES 151
>AF017724-1|AAC39919.1| 465|Homo sapiens glycine receptor alpha 3
subunit protein.
Length = 465
Score = 40.7 bits (91), Expect = 0.007
Identities = 30/135 (22%), Positives = 58/135 (42%), Gaps = 4/135 (2%)
Frame = +2
Query: 182 PDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIGKRLSWNAGEWGCSTWLVSS-ERL 358
P + N+ ++ +I E+ R+ L+ W RL+++ S + +
Sbjct: 68 PPVNVTCNIFIN-SFGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPDDSLDLDPSMLDSI 126
Query: 359 WRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCT 529
W+PD+ N + R+ NG+V + RL ++ M L N+P D+QTC
Sbjct: 127 WKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFPMDVQTCI 186
Query: 530 FKFGSRMHXSDEMDF 574
+ S + +++ F
Sbjct: 187 MQLESFGYTMNDLIF 201
>X15376-1|CAA33437.1| 467|Homo sapiens GABA-A receptor gamma 2
subunit protein.
Length = 467
Score = 40.3 bits (90), Expect = 0.009
Identities = 33/156 (21%), Positives = 66/156 (42%), Gaps = 7/156 (4%)
Frame = +2
Query: 131 LSLMIDSLLATYDRDSPPDSKIVVNLTLHLRHANIRESESTVRIQADLQM----NWIGKR 298
+++++++LL YD PD + L + N + + ++ + + W +R
Sbjct: 66 VTVILNNLLEGYDNKLRPDIGVKPTLIHTDMYVNSIGPVNAINMEYTIDIFFAQMWYDRR 125
Query: 299 LSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYAL---RARVSNNGSVSWIKRLD 469
L +N+ ++W PD N+ A R+ N+G V + RL
Sbjct: 126 LKFNSTIKVLRLNSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYSLRLT 185
Query: 470 ISTPISMQLDNWPNDMQTCTFKFGSRMHXSDEMDFR 577
I +QL N+P D +C +F S + +E+ ++
Sbjct: 186 IDAECQLQLHNFPMDEHSCPLEFSSYGYPREEIVYQ 221
>BC114967-1|AAI14968.1| 366|Homo sapiens GLRA1 protein protein.
Length = 366
Score = 40.3 bits (90), Expect = 0.009
Identities = 27/110 (24%), Positives = 49/110 (44%), Gaps = 4/110 (3%)
Frame = +2
Query: 257 RIQADLQMNWIGKRLSWNAGEWGCSTWLVSS-ERLWRPDVVLLNAAATTAGDYALR---A 424
R+ L+ W RL++N S + +W+PD+ N +
Sbjct: 4 RVNIFLRQQWNDPRLAYNEYPDDSLDLDPSMLDSIWKPDLFFANEKGAHFHEITTDNKLL 63
Query: 425 RVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXSDEMDF 574
R+S NG+V + R+ ++ M L N+P D+QTC + S + +++ F
Sbjct: 64 RISRNGNVLYSIRITLTLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIF 113
>AB209359-1|BAD92596.1| 533|Homo sapiens cholinergic receptor,
nicotinic, alpha polypeptide 4 precursor variant
protein.
Length = 533
Score = 35.5 bits (78), Expect = 0.25
Identities = 19/72 (26%), Positives = 32/72 (44%)
Frame = +2
Query: 356 LWRPDVVLLNAAATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFK 535
LW +A A + +A + ++G V W + S+ + +P D Q CT K
Sbjct: 25 LWLCCCTFTSADGDFAVTHLTKAHLFHDGRVQWTPPAIYKSSCSIDVTFFPFDQQNCTMK 84
Query: 536 FGSRMHXSDEMD 571
FGS + ++D
Sbjct: 85 FGSWTYDKAKID 96
>BC096291-1|AAH96291.1| 556|Homo sapiens CHRNA4 protein protein.
Length = 556
Score = 34.7 bits (76), Expect = 0.44
Identities = 18/60 (30%), Positives = 31/60 (51%), Gaps = 4/60 (6%)
Frame = +2
Query: 404 GDYAL----RARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXSDEMD 571
GD+A+ +A + ++G V W + S+ + +P D Q CT KFGS + ++D
Sbjct: 60 GDFAVTHLTKAHLFHDGRVQWTPPAIYKSSCSIDVTFFPFDQQNCTMKFGSWTYDKAKID 119
>S80905-1|AAB50686.1| 382|Homo sapiens Con1 protein.
Length = 382
Score = 33.5 bits (73), Expect = 1.0
Identities = 16/39 (41%), Positives = 18/39 (46%), Gaps = 1/39 (2%)
Frame = -3
Query: 851 GEPRXPPPXGGXXGRXXRXPXGXQXG-GTXXGEXXXGPP 738
G+P+ PPP GG R R P G G G GPP
Sbjct: 247 GKPQGPPPQGGSKSRSSRSPPGKPQGPPPQGGNQPQGPP 285
Score = 33.5 bits (73), Expect = 1.0
Identities = 16/39 (41%), Positives = 18/39 (46%), Gaps = 1/39 (2%)
Frame = -3
Query: 851 GEPRXPPPXGGXXGRXXRXPXGXQXG-GTXXGEXXXGPP 738
G+P+ PPP GG R R P G G G GPP
Sbjct: 309 GKPQGPPPQGGSKSRSARSPPGKPQGPPQQEGNNPQGPP 347
Score = 30.7 bits (66), Expect = 7.2
Identities = 15/39 (38%), Positives = 17/39 (43%), Gaps = 1/39 (2%)
Frame = -3
Query: 851 GEPRXPPPXGGXXGRXXRXPXGXQXG-GTXXGEXXXGPP 738
G+P+ PPP G R R P G G G GPP
Sbjct: 123 GKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQGPP 161
>K03208-1|AAA60189.1| 251|Homo sapiens PRB2 protein.
Length = 251
Score = 33.5 bits (73), Expect = 1.0
Identities = 16/39 (41%), Positives = 18/39 (46%), Gaps = 1/39 (2%)
Frame = -3
Query: 851 GEPRXPPPXGGXXGRXXRXPXGXQXG-GTXXGEXXXGPP 738
G+P+ PPP GG R R P G G G GPP
Sbjct: 116 GKPQGPPPQGGSKSRSSRSPPGKPQGPPPQGGNQPQGPP 154
Score = 33.5 bits (73), Expect = 1.0
Identities = 16/39 (41%), Positives = 18/39 (46%), Gaps = 1/39 (2%)
Frame = -3
Query: 851 GEPRXPPPXGGXXGRXXRXPXGXQXG-GTXXGEXXXGPP 738
G+P+ PPP GG R R P G G G GPP
Sbjct: 178 GKPQGPPPQGGSKSRSARSPPGKPQGPPQQEGNNPQGPP 216
>K02575-1|AAA36502.1| 173|Homo sapiens protein ( Human salivary
proline-rich protein 1 gene, segment 1. ).
Length = 173
Score = 33.5 bits (73), Expect = 1.0
Identities = 16/39 (41%), Positives = 18/39 (46%), Gaps = 1/39 (2%)
Frame = -3
Query: 851 GEPRXPPPXGGXXGRXXRXPXGXQXG-GTXXGEXXXGPP 738
G+P+ PPP GG R R P G G G GPP
Sbjct: 58 GKPQGPPPQGGKRSRSPRSPPGKPQGPPPQGGNQPQGPP 96
>S62941-1|AAB27289.1| 358|Homo sapiens Ps 2 protein.
Length = 358
Score = 31.9 bits (69), Expect = 3.1
Identities = 15/39 (38%), Positives = 18/39 (46%), Gaps = 1/39 (2%)
Frame = -3
Query: 851 GEPRXPPPXGGXXGRXXRXPXGXQXG-GTXXGEXXXGPP 738
G+P+ PPP GG + R P G G G GPP
Sbjct: 285 GKPQGPPPQGGSKSQSARAPPGKPQGPPQQEGNNPQGPP 323
>BC146774-1|AAI46775.1| 1114|Homo sapiens GPR124 protein protein.
Length = 1114
Score = 31.9 bits (69), Expect = 3.1
Identities = 20/70 (28%), Positives = 34/70 (48%), Gaps = 1/70 (1%)
Frame = +2
Query: 260 IQADLQMNWIGKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNN 439
I ++L ++ IG W +GEW C+ + + ++V+L T+ Y RV+NN
Sbjct: 302 ITSELTLSHIGV---WASGEWECTVSMAQGNASKKVEIVVLE----TSASYCPAERVANN 354
Query: 440 -GSVSWIKRL 466
G W + L
Sbjct: 355 RGDFRWPRTL 364
>AY181242-1|AAO27354.1| 1331|Homo sapiens G protein-coupled receptor
124 protein.
Length = 1331
Score = 31.9 bits (69), Expect = 3.1
Identities = 20/70 (28%), Positives = 34/70 (48%), Gaps = 1/70 (1%)
Frame = +2
Query: 260 IQADLQMNWIGKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNN 439
I ++L ++ IG W +GEW C+ + + ++V+L T+ Y RV+NN
Sbjct: 302 ITSELTLSHIGV---WASGEWECTVSMAQGNASKKVEIVVLE----TSASYCPAERVANN 354
Query: 440 -GSVSWIKRL 466
G W + L
Sbjct: 355 RGDFRWPRTL 364
>AK074099-1|BAB84925.1| 1310|Homo sapiens FLJ00170 protein protein.
Length = 1310
Score = 31.9 bits (69), Expect = 3.1
Identities = 20/70 (28%), Positives = 34/70 (48%), Gaps = 1/70 (1%)
Frame = +2
Query: 260 IQADLQMNWIGKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNN 439
I ++L ++ IG W +GEW C+ + + ++V+L T+ Y RV+NN
Sbjct: 281 ITSELTLSHIGV---WASGEWECTVSMAQGNASKKVEIVVLE----TSASYCPAERVANN 333
Query: 440 -GSVSWIKRL 466
G W + L
Sbjct: 334 RGDFRWPRTL 343
>AF378755-1|AAL11992.1| 1331|Homo sapiens tumor endothelial marker 5
precursor protein.
Length = 1331
Score = 31.9 bits (69), Expect = 3.1
Identities = 20/70 (28%), Positives = 34/70 (48%), Gaps = 1/70 (1%)
Frame = +2
Query: 260 IQADLQMNWIGKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNN 439
I ++L ++ IG W +GEW C+ + + ++V+L T+ Y RV+NN
Sbjct: 302 ITSELTLSHIGV---WASGEWECTVSMAQGNASKKVEIVVLE----TSASYCPAERVANN 354
Query: 440 -GSVSWIKRL 466
G W + L
Sbjct: 355 RGDFRWPRTL 364
>AB040964-1|BAA96055.2| 1206|Homo sapiens KIAA1531 protein protein.
Length = 1206
Score = 31.9 bits (69), Expect = 3.1
Identities = 20/70 (28%), Positives = 34/70 (48%), Gaps = 1/70 (1%)
Frame = +2
Query: 260 IQADLQMNWIGKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNN 439
I ++L ++ IG W +GEW C+ + + ++V+L T+ Y RV+NN
Sbjct: 394 ITSELTLSHIGV---WASGEWECTVSMAQGNASKKVEIVVLE----TSASYCPAERVANN 446
Query: 440 -GSVSWIKRL 466
G W + L
Sbjct: 447 RGDFRWPRTL 456
>U83981-1|AAC25631.1| 674|Homo sapiens apoptosis associated protein
protein.
Length = 674
Score = 31.1 bits (67), Expect = 5.4
Identities = 17/46 (36%), Positives = 22/46 (47%), Gaps = 1/46 (2%)
Frame = -3
Query: 431 IHGRGERSPRRWLQPRLAVPRQASTSVPRTPAKCCSP-TPLRSNSV 297
I+ GE+ P W PRL + Q P TP P TPL++ V
Sbjct: 511 IYVPGEKPPPPWAPPRLPLRLQRRLKRPETPTHDPDPETPLKARKV 556
>CR457259-1|CAG33540.1| 674|Homo sapiens PPP1R15A protein.
Length = 674
Score = 31.1 bits (67), Expect = 5.4
Identities = 17/46 (36%), Positives = 22/46 (47%), Gaps = 1/46 (2%)
Frame = -3
Query: 431 IHGRGERSPRRWLQPRLAVPRQASTSVPRTPAKCCSP-TPLRSNSV 297
I+ GE+ P W PRL + Q P TP P TPL++ V
Sbjct: 511 IYVPGEKPPPPWAPPRLPLRLQRRLKRPETPTHDPDPETPLKARKV 556
>BC003067-1|AAH03067.1| 674|Homo sapiens protein phosphatase 1,
regulatory (inhibitor) subunit 15A protein.
Length = 674
Score = 31.1 bits (67), Expect = 5.4
Identities = 17/46 (36%), Positives = 22/46 (47%), Gaps = 1/46 (2%)
Frame = -3
Query: 431 IHGRGERSPRRWLQPRLAVPRQASTSVPRTPAKCCSP-TPLRSNSV 297
I+ GE+ P W PRL + Q P TP P TPL++ V
Sbjct: 511 IYVPGEKPPPPWAPPRLPLRLQRRLKRPETPTHDPDPETPLKARKV 556
>AK001361-1|BAA91649.1| 674|Homo sapiens protein ( Homo sapiens
cDNA FLJ10499 fis, clone NT2RP2000346, weakly similar to
MYELOID DIFFERENTIATION PRIMARY RESPONSE PROTEIN MYD116.
).
Length = 674
Score = 31.1 bits (67), Expect = 5.4
Identities = 17/46 (36%), Positives = 22/46 (47%), Gaps = 1/46 (2%)
Frame = -3
Query: 431 IHGRGERSPRRWLQPRLAVPRQASTSVPRTPAKCCSP-TPLRSNSV 297
I+ GE+ P W PRL + Q P TP P TPL++ V
Sbjct: 511 IYVPGEKPPPPWAPPRLPLRLQRRLKRPETPTHDPDPETPLKARKV 556
>K03206-1|AAA60187.1| 178|Homo sapiens PRB1 protein.
Length = 178
Score = 30.3 bits (65), Expect = 9.5
Identities = 15/38 (39%), Positives = 17/38 (44%)
Frame = -3
Query: 851 GEPRXPPPXGGXXGRXXRXPXGXQXGGTXXGEXXXGPP 738
G+P+ PPP G R R P G G G GPP
Sbjct: 75 GKPQGPPPQGD-KSRSPRSPPGKPQGPPPQGGKPQGPP 111
>K03205-1|AAA60186.1| 198|Homo sapiens PRB1 protein.
Length = 198
Score = 30.3 bits (65), Expect = 9.5
Identities = 15/38 (39%), Positives = 17/38 (44%)
Frame = -3
Query: 851 GEPRXPPPXGGXXGRXXRXPXGXQXGGTXXGEXXXGPP 738
G+P+ PPP G R R P G G G GPP
Sbjct: 75 GKPQGPPPQGD-KSRSPRSPPGKPQGPPPQGGKPQGPP 111
>BC141917-1|AAI41918.1| 198|Homo sapiens PRB1 protein protein.
Length = 198
Score = 30.3 bits (65), Expect = 9.5
Identities = 15/38 (39%), Positives = 17/38 (44%)
Frame = -3
Query: 851 GEPRXPPPXGGXXGRXXRXPXGXQXGGTXXGEXXXGPP 738
G+P+ PPP G R R P G G G GPP
Sbjct: 75 GKPQGPPPQGD-KSRSPRSPPGKPQGPPPQGGKPQGPP 111
>AK122582-1|BAC56923.1| 1383|Homo sapiens FLJ00269 protein protein.
Length = 1383
Score = 30.3 bits (65), Expect = 9.5
Identities = 13/38 (34%), Positives = 18/38 (47%)
Frame = -3
Query: 428 HGRGERSPRRWLQPRLAVPRQASTSVPRTPAKCCSPTP 315
HG + SP W Q + + P + P P +CCS P
Sbjct: 256 HGGRDCSPTCWEQGKCSGPAEQEKRGPSFPKECCSQGP 293
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 129,249,543
Number of Sequences: 237096
Number of extensions: 3097460
Number of successful extensions: 8104
Number of sequences better than 10.0: 186
Number of HSP's better than 10.0 without gapping: 7034
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 7947
length of database: 76,859,062
effective HSP length: 90
effective length of database: 55,520,422
effective search space used: 11048563978
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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