Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BmNP07_T7_O14
(780 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
U59151-1|AAB94299.1| 514|Homo sapiens Cbf5p homolog protein. 218 2e-56
BC010015-1|AAH10015.1| 514|Homo sapiens dyskeratosis congenita ... 218 2e-56
BC009928-1|AAH09928.1| 514|Homo sapiens dyskeratosis congenita ... 218 2e-56
AJ224481-1|CAA11970.1| 514|Homo sapiens dyskerin protein. 218 2e-56
AF067023-1|AAD20232.1| 514|Homo sapiens dyskerin protein. 218 2e-56
AF067008-1|AAD11815.1| 514|Homo sapiens dyskerin protein. 218 2e-56
AJ010395-1|CAB51168.1| 524|Homo sapiens dyskerin protein. 214 3e-55
>U59151-1|AAB94299.1| 514|Homo sapiens Cbf5p homolog protein.
Length = 514
Score = 218 bits (533), Expect = 2e-56
Identities = 103/206 (50%), Positives = 147/206 (71%), Gaps = 12/206 (5%)
Frame = -3
Query: 628 AHKRIFIKDSAVNAVCYGAKVLLPGILRYEDGIEVDQEIVIVTTKGEAVALAVALMTTST 449
+HKR+ +KDSAVNA+CYGAK++LPG+LRYEDGIEV+QEIV++TTKGEA+ +A+ALMTT+
Sbjct: 295 SHKRLVMKDSAVNAICYGAKIMLPGVLRYEDGIEVNQEIVVITTKGEAICMAIALMTTAV 354
Query: 448 MASCDHGVAAKLKRVIMERDTYPRKWGLGPKASQKKILIQQGKLDKYGKPNENTPKEWLN 269
+++CDHG+ AK+KRVIMERDTYPRKWGLGPKASQKK++I+QG LDK+GKP ++TP W
Sbjct: 355 ISTCDHGIVAKIKRVIMERDTYPRKWGLGPKASQKKLMIKQGLLDKHGKPTDSTPATWKQ 414
Query: 268 SYVNYN----------VKKEPE-NGDGVEEGSRKRTASTANAEDPDVSIE-VKQEXXXXX 125
YV+Y+ V K P+ + + RKR + + + E P + + +K+E
Sbjct: 415 EYVDYSESAKKEVVAEVVKAPQVVAEAAKTAKRKRESESESDETPPAAPQLIKKEKKKSK 474
Query: 124 XKRDSEAPAEADATMDTSESPETAEQ 47
+ ++A E+ A +S T ++
Sbjct: 475 KDKKAKAGLESGAEPGDGDSDTTKKK 500
Score = 67.7 bits (158), Expect = 4e-11
Identities = 30/47 (63%), Positives = 36/47 (76%)
Frame = -1
Query: 744 EKEGMVXMHDILDAQWSYENHKDETYLRRVIKPLEGLLMLTKGYLSK 604
EK+ MV MHD+LDAQW Y+NHKDE+YLRRV+ PLE LL K + K
Sbjct: 256 EKDHMVTMHDVLDAQWLYDNHKDESYLRRVVYPLEKLLTSHKRLVMK 302
>BC010015-1|AAH10015.1| 514|Homo sapiens dyskeratosis congenita 1,
dyskerin protein.
Length = 514
Score = 218 bits (533), Expect = 2e-56
Identities = 103/206 (50%), Positives = 147/206 (71%), Gaps = 12/206 (5%)
Frame = -3
Query: 628 AHKRIFIKDSAVNAVCYGAKVLLPGILRYEDGIEVDQEIVIVTTKGEAVALAVALMTTST 449
+HKR+ +KDSAVNA+CYGAK++LPG+LRYEDGIEV+QEIV++TTKGEA+ +A+ALMTT+
Sbjct: 295 SHKRLVMKDSAVNAICYGAKIMLPGVLRYEDGIEVNQEIVVITTKGEAICMAIALMTTAV 354
Query: 448 MASCDHGVAAKLKRVIMERDTYPRKWGLGPKASQKKILIQQGKLDKYGKPNENTPKEWLN 269
+++CDHG+ AK+KRVIMERDTYPRKWGLGPKASQKK++I+QG LDK+GKP ++TP W
Sbjct: 355 ISTCDHGIVAKIKRVIMERDTYPRKWGLGPKASQKKLMIKQGLLDKHGKPTDSTPATWKQ 414
Query: 268 SYVNYN----------VKKEPE-NGDGVEEGSRKRTASTANAEDPDVSIE-VKQEXXXXX 125
YV+Y+ V K P+ + + RKR + + + E P + + +K+E
Sbjct: 415 EYVDYSESAKKEVVAEVVKAPQVVAEAAKTAKRKRESESESDETPPAAPQLIKKEKKKSK 474
Query: 124 XKRDSEAPAEADATMDTSESPETAEQ 47
+ ++A E+ A +S T ++
Sbjct: 475 KDKKAKAGLESGAEPGDGDSDTTKKK 500
Score = 67.7 bits (158), Expect = 4e-11
Identities = 30/47 (63%), Positives = 36/47 (76%)
Frame = -1
Query: 744 EKEGMVXMHDILDAQWSYENHKDETYLRRVIKPLEGLLMLTKGYLSK 604
EK+ MV MHD+LDAQW Y+NHKDE+YLRRV+ PLE LL K + K
Sbjct: 256 EKDHMVTMHDVLDAQWLYDNHKDESYLRRVVYPLEKLLTSHKRLVMK 302
>BC009928-1|AAH09928.1| 514|Homo sapiens dyskeratosis congenita 1,
dyskerin protein.
Length = 514
Score = 218 bits (533), Expect = 2e-56
Identities = 103/206 (50%), Positives = 147/206 (71%), Gaps = 12/206 (5%)
Frame = -3
Query: 628 AHKRIFIKDSAVNAVCYGAKVLLPGILRYEDGIEVDQEIVIVTTKGEAVALAVALMTTST 449
+HKR+ +KDSAVNA+CYGAK++LPG+LRYEDGIEV+QEIV++TTKGEA+ +A+ALMTT+
Sbjct: 295 SHKRLVMKDSAVNAICYGAKIMLPGVLRYEDGIEVNQEIVVITTKGEAICMAIALMTTAV 354
Query: 448 MASCDHGVAAKLKRVIMERDTYPRKWGLGPKASQKKILIQQGKLDKYGKPNENTPKEWLN 269
+++CDHG+ AK+KRVIMERDTYPRKWGLGPKASQKK++I+QG LDK+GKP ++TP W
Sbjct: 355 ISTCDHGIVAKIKRVIMERDTYPRKWGLGPKASQKKLMIKQGLLDKHGKPTDSTPATWKQ 414
Query: 268 SYVNYN----------VKKEPE-NGDGVEEGSRKRTASTANAEDPDVSIE-VKQEXXXXX 125
YV+Y+ V K P+ + + RKR + + + E P + + +K+E
Sbjct: 415 EYVDYSESAKKEVVAEVVKAPQVVAEAAKTAKRKRESESESDETPPAAPQLIKKEKKKSK 474
Query: 124 XKRDSEAPAEADATMDTSESPETAEQ 47
+ ++A E+ A +S T ++
Sbjct: 475 KDKKAKAGLESGAEPGDGDSDTTKKK 500
Score = 65.7 bits (153), Expect = 2e-10
Identities = 29/47 (61%), Positives = 35/47 (74%)
Frame = -1
Query: 744 EKEGMVXMHDILDAQWSYENHKDETYLRRVIKPLEGLLMLTKGYLSK 604
EK+ MV MHD+LDAQW Y+NHKDE+YLRR + PLE LL K + K
Sbjct: 256 EKDHMVTMHDVLDAQWLYDNHKDESYLRRFVYPLEKLLTSHKRLVMK 302
>AJ224481-1|CAA11970.1| 514|Homo sapiens dyskerin protein.
Length = 514
Score = 218 bits (533), Expect = 2e-56
Identities = 103/206 (50%), Positives = 147/206 (71%), Gaps = 12/206 (5%)
Frame = -3
Query: 628 AHKRIFIKDSAVNAVCYGAKVLLPGILRYEDGIEVDQEIVIVTTKGEAVALAVALMTTST 449
+HKR+ +KDSAVNA+CYGAK++LPG+LRYEDGIEV+QEIV++TTKGEA+ +A+ALMTT+
Sbjct: 295 SHKRLVMKDSAVNAICYGAKIMLPGVLRYEDGIEVNQEIVVITTKGEAICMAIALMTTAV 354
Query: 448 MASCDHGVAAKLKRVIMERDTYPRKWGLGPKASQKKILIQQGKLDKYGKPNENTPKEWLN 269
+++CDHG+ AK+KRVIMERDTYPRKWGLGPKASQKK++I+QG LDK+GKP ++TP W
Sbjct: 355 ISTCDHGIVAKIKRVIMERDTYPRKWGLGPKASQKKLMIKQGLLDKHGKPTDSTPATWKQ 414
Query: 268 SYVNYN----------VKKEPE-NGDGVEEGSRKRTASTANAEDPDVSIE-VKQEXXXXX 125
YV+Y+ V K P+ + + RKR + + + E P + + +K+E
Sbjct: 415 EYVDYSESAKKEVVAEVVKAPQVVAEAAKTAKRKRESESESDETPPAAPQLIKKEKKKSK 474
Query: 124 XKRDSEAPAEADATMDTSESPETAEQ 47
+ ++A E+ A +S T ++
Sbjct: 475 KDKKAKAGLESGAEPGDGDSDTTKKK 500
Score = 67.7 bits (158), Expect = 4e-11
Identities = 30/47 (63%), Positives = 36/47 (76%)
Frame = -1
Query: 744 EKEGMVXMHDILDAQWSYENHKDETYLRRVIKPLEGLLMLTKGYLSK 604
EK+ MV MHD+LDAQW Y+NHKDE+YLRRV+ PLE LL K + K
Sbjct: 256 EKDHMVTMHDVLDAQWLYDNHKDESYLRRVVYPLEKLLTSHKRLVMK 302
>AF067023-1|AAD20232.1| 514|Homo sapiens dyskerin protein.
Length = 514
Score = 218 bits (533), Expect = 2e-56
Identities = 103/206 (50%), Positives = 147/206 (71%), Gaps = 12/206 (5%)
Frame = -3
Query: 628 AHKRIFIKDSAVNAVCYGAKVLLPGILRYEDGIEVDQEIVIVTTKGEAVALAVALMTTST 449
+HKR+ +KDSAVNA+CYGAK++LPG+LRYEDGIEV+QEIV++TTKGEA+ +A+ALMTT+
Sbjct: 295 SHKRLVMKDSAVNAICYGAKIMLPGVLRYEDGIEVNQEIVVITTKGEAICMAIALMTTAV 354
Query: 448 MASCDHGVAAKLKRVIMERDTYPRKWGLGPKASQKKILIQQGKLDKYGKPNENTPKEWLN 269
+++CDHG+ AK+KRVIMERDTYPRKWGLGPKASQKK++I+QG LDK+GKP ++TP W
Sbjct: 355 ISTCDHGIVAKIKRVIMERDTYPRKWGLGPKASQKKLMIKQGLLDKHGKPTDSTPATWKQ 414
Query: 268 SYVNYN----------VKKEPE-NGDGVEEGSRKRTASTANAEDPDVSIE-VKQEXXXXX 125
YV+Y+ V K P+ + + RKR + + + E P + + +K+E
Sbjct: 415 EYVDYSESAKKEVVAEVVKAPQVVAEAAKTAKRKRESESESDETPPAAPQLIKKEKKKSK 474
Query: 124 XKRDSEAPAEADATMDTSESPETAEQ 47
+ ++A E+ A +S T ++
Sbjct: 475 KDKKAKAGLESGAEPGDGDSDTTKKK 500
Score = 67.7 bits (158), Expect = 4e-11
Identities = 30/47 (63%), Positives = 36/47 (76%)
Frame = -1
Query: 744 EKEGMVXMHDILDAQWSYENHKDETYLRRVIKPLEGLLMLTKGYLSK 604
EK+ MV MHD+LDAQW Y+NHKDE+YLRRV+ PLE LL K + K
Sbjct: 256 EKDHMVTMHDVLDAQWLYDNHKDESYLRRVVYPLEKLLTSHKRLVMK 302
>AF067008-1|AAD11815.1| 514|Homo sapiens dyskerin protein.
Length = 514
Score = 218 bits (533), Expect = 2e-56
Identities = 103/206 (50%), Positives = 147/206 (71%), Gaps = 12/206 (5%)
Frame = -3
Query: 628 AHKRIFIKDSAVNAVCYGAKVLLPGILRYEDGIEVDQEIVIVTTKGEAVALAVALMTTST 449
+HKR+ +KDSAVNA+CYGAK++LPG+LRYEDGIEV+QEIV++TTKGEA+ +A+ALMTT+
Sbjct: 295 SHKRLVMKDSAVNAICYGAKIMLPGVLRYEDGIEVNQEIVVITTKGEAICMAIALMTTAV 354
Query: 448 MASCDHGVAAKLKRVIMERDTYPRKWGLGPKASQKKILIQQGKLDKYGKPNENTPKEWLN 269
+++CDHG+ AK+KRVIMERDTYPRKWGLGPKASQKK++I+QG LDK+GKP ++TP W
Sbjct: 355 ISTCDHGIVAKIKRVIMERDTYPRKWGLGPKASQKKLMIKQGLLDKHGKPTDSTPATWKQ 414
Query: 268 SYVNYN----------VKKEPE-NGDGVEEGSRKRTASTANAEDPDVSIE-VKQEXXXXX 125
YV+Y+ V K P+ + + RKR + + + E P + + +K+E
Sbjct: 415 EYVDYSESAKKEVVAEVVKAPQVVAEAAKTAKRKRESESESDETPPAAPQLIKKEKKKSK 474
Query: 124 XKRDSEAPAEADATMDTSESPETAEQ 47
+ ++A E+ A +S T ++
Sbjct: 475 KDKKAKAGLESGAEPGDGDSDTTKKK 500
Score = 67.7 bits (158), Expect = 4e-11
Identities = 30/47 (63%), Positives = 36/47 (76%)
Frame = -1
Query: 744 EKEGMVXMHDILDAQWSYENHKDETYLRRVIKPLEGLLMLTKGYLSK 604
EK+ MV MHD+LDAQW Y+NHKDE+YLRRV+ PLE LL K + K
Sbjct: 256 EKDHMVTMHDVLDAQWLYDNHKDESYLRRVVYPLEKLLTSHKRLVMK 302
>AJ010395-1|CAB51168.1| 524|Homo sapiens dyskerin protein.
Length = 524
Score = 214 bits (523), Expect = 3e-55
Identities = 91/132 (68%), Positives = 118/132 (89%), Gaps = 2/132 (1%)
Frame = -3
Query: 628 AHKRIFIKDSAVNAVCYGAKVLLPGILRYEDGIEVDQEIVIVTTKGEAVALAVALMTTST 449
+HKR+ +KDSAVNA+CYGAK++LPG+LRYEDGIEV+QEIV++TTKGEA+ +A+ALMTT+
Sbjct: 295 SHKRLVMKDSAVNAICYGAKIMLPGVLRYEDGIEVNQEIVVITTKGEAICMAIALMTTAV 354
Query: 448 MASCDHGVAAKLKRVIMERDTYPRKWGLGPKASQKKILIQQGKLDKYGKPNENTPKEWLN 269
+++CDHG+ AK+KRVIMERDTYPRKWGLGPKASQKK++I+QG LDK+GKP ++TP W
Sbjct: 355 ISTCDHGIVAKIKRVIMERDTYPRKWGLGPKASQKKLMIKQGLLDKHGKPTDSTPATWKQ 414
Query: 268 SYVNY--NVKKE 239
YV+Y + KKE
Sbjct: 415 EYVDYSESAKKE 426
Score = 67.7 bits (158), Expect = 4e-11
Identities = 30/47 (63%), Positives = 36/47 (76%)
Frame = -1
Query: 744 EKEGMVXMHDILDAQWSYENHKDETYLRRVIKPLEGLLMLTKGYLSK 604
EK+ MV MHD+LDAQW Y+NHKDE+YLRRV+ PLE LL K + K
Sbjct: 256 EKDHMVTMHDVLDAQWLYDNHKDESYLRRVVYPLEKLLTSHKRLVMK 302
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 102,084,014
Number of Sequences: 237096
Number of extensions: 2037139
Number of successful extensions: 5064
Number of sequences better than 10.0: 7
Number of HSP's better than 10.0 without gapping: 4766
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5062
length of database: 76,859,062
effective HSP length: 89
effective length of database: 55,757,518
effective search space used: 9478778060
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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