Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BmNP07_FL5_N13
(862 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
AJ306454-1|CAC34819.1| 497|Homo sapiens neuronal nicotinic acet... 63 1e-09
Y08416-1|CAA69693.1| 498|Homo sapiens nicotinic acetylcholine r... 61 6e-09
U62439-1|AAB40117.1| 498|Homo sapiens nicotinic acetylcholine r... 61 6e-09
U48861-1|AAA92123.1| 498|Homo sapiens beta 4 nicotinic acetylch... 61 6e-09
BC096082-1|AAH96082.1| 498|Homo sapiens cholinergic receptor, n... 61 6e-09
BC096080-1|AAH96080.1| 498|Homo sapiens cholinergic receptor, n... 61 6e-09
AF306329-1|AAL02062.1| 498|Homo sapiens neuronal nicotinic acet... 61 6e-09
Y08417-1|CAA69694.1| 458|Homo sapiens nicotinic acetylcholine r... 59 2e-08
X67513-1|CAA47851.1| 423|Homo sapiens nicotinic acetylcholine ... 59 2e-08
U62438-1|AAB40116.1| 458|Homo sapiens nicotinic acetylcholine r... 59 2e-08
BC069788-1|AAH69788.1| 458|Homo sapiens cholinergic receptor, n... 59 2e-08
BC069703-1|AAH69703.1| 458|Homo sapiens cholinergic receptor, n... 59 2e-08
BC069681-1|AAH69681.1| 458|Homo sapiens cholinergic receptor, n... 59 2e-08
AF140765-1|AAD33063.1| 458|Homo sapiens neuronal acetylcholine ... 59 2e-08
Y08419-1|CAA69696.1| 468|Homo sapiens nicotinic acetylcholine r... 58 4e-08
U62434-1|AAB40112.1| 468|Homo sapiens nicotinic acetylcholine r... 58 4e-08
BC033639-1|AAH33639.1| 468|Homo sapiens cholinergic receptor, n... 58 4e-08
AJ306481-1|CAC34820.1| 468|Homo sapiens neuronal nicotinic acet... 58 4e-08
X14830-1|CAA32939.1| 501|Homo sapiens protein ( Human mRNA for ... 57 7e-08
BC011371-1|AAH11371.1| 501|Homo sapiens cholinergic receptor, n... 57 7e-08
Y08418-1|CAA69695.1| 503|Homo sapiens nicotinic acetylcholine r... 57 9e-08
X53559-1|CAA37625.1| 474|Homo sapiens neuronal nicotinic acetyl... 57 9e-08
U62432-1|AAB40110.1| 504|Homo sapiens nicotinic acetylcholine r... 57 9e-08
M83712-1|AAA58357.1| 468|Homo sapiens nicotinic receptor alpha ... 57 9e-08
M37981-1|AAA59942.1| 503|Homo sapiens neuronal nicotinic acetyl... 57 9e-08
BT006897-1|AAP35543.1| 505|Homo sapiens cholinergic receptor, n... 57 9e-08
BT006646-1|AAP35292.1| 489|Homo sapiens cholinergic receptor, n... 57 9e-08
BC098443-1|AAH98443.1| 504|Homo sapiens cholinergic receptor, n... 57 9e-08
BC006114-1|AAH06114.1| 489|Homo sapiens CHRNA3 protein protein. 57 9e-08
BC002996-1|AAH02996.1| 505|Homo sapiens cholinergic receptor, n... 57 9e-08
BC001642-1|AAH01642.1| 505|Homo sapiens cholinergic receptor, n... 57 9e-08
BC000513-1|AAH00513.1| 505|Homo sapiens cholinergic receptor, n... 57 9e-08
AJ007783-1|CAA07682.1| 504|Homo sapiens nicotinic acetylcholine... 57 9e-08
AF385584-1|AAK68110.1| 489|Homo sapiens nicotinic cholinergic r... 57 9e-08
X68275-1|CAA48336.1| 451|Homo sapiens nicotinic receptor beta 4... 56 1e-07
BC023553-1|AAH23553.1| 501|Homo sapiens cholinergic receptor, n... 56 2e-07
X66403-1|CAA47030.1| 493|Homo sapiens acetylcholine receptor ep... 55 3e-07
AF105999-1|AAD24503.1| 493|Homo sapiens acetylcholine receptor ... 55 3e-07
Y16282-1|CAA76155.1| 494|Homo sapiens nicotinic acetylcholine r... 54 5e-07
Y16281-1|CAA76154.1| 529|Homo sapiens nicotinic acetylcholine r... 54 5e-07
U62435-1|AAB40113.1| 494|Homo sapiens nicotinic acetylcholine r... 54 5e-07
U62431-1|AAB40109.1| 529|Homo sapiens nicotinic acetylcholine r... 54 5e-07
M86383-1|AAC84176.1| 502|Homo sapiens nicotinic acetylcholine r... 54 5e-07
BC014456-1|AAH14456.1| 494|Homo sapiens cholinergic receptor, n... 54 5e-07
AB079251-1|BAC06855.1| 494|Homo sapiens Nicotinic acetylcholine... 54 5e-07
Y08421-1|CAA69698.1| 627|Homo sapiens nicotinic acetylcholine r... 53 1e-06
X89741-1|CAA61893.1| 627|Homo sapiens neuronal acetylcholine re... 53 1e-06
X87629-1|CAA60959.1| 602|Homo sapiens nicotinic acetylcholine r... 53 1e-06
U62433-1|AAB40111.1| 627|Homo sapiens nicotinic acetylcholine r... 53 1e-06
L35901-1|AAA64743.1| 627|Homo sapiens nicotinic acetylcholine r... 53 1e-06
DQ093071-1|AAY88737.1| 627|Homo sapiens cholinergic receptor, n... 53 1e-06
BC096290-1|AAH96290.1| 627|Homo sapiens cholinergic receptor, n... 53 1e-06
X01715-1|CAA25861.1| 520|Homo sapiens acetylcholine receptor ga... 52 2e-06
AC092165-3|AAY24103.1| 520|Homo sapiens unknown protein. 52 2e-06
BC113575-1|AAI13576.1| 479|Homo sapiens cholinergic receptor, n... 52 4e-06
BC113549-1|AAI13550.1| 479|Homo sapiens cholinergic receptor, n... 52 4e-06
AY123244-1|AAM74523.1| 479|Homo sapiens nicotinic acetylcholine... 52 4e-06
AJ243342-1|CAB65091.1| 479|Homo sapiens nicotinic acetylcholine... 52 4e-06
AF227732-1|AAF61920.1| 470|Homo sapiens nicotinic acetylcholine... 52 4e-06
AC118275-1|AAY40986.1| 479|Homo sapiens unknown protein. 52 4e-06
Y08415-1|CAA69692.1| 502|Homo sapiens nicotinic acetylcholine r... 50 8e-06
X53179-1|CAA37320.1| 502|Homo sapiens precursor peptide (AA -25... 50 8e-06
U62437-1|AAB40115.1| 502|Homo sapiens nicotinic acetylcholine r... 50 8e-06
BC075041-1|AAH75041.1| 502|Homo sapiens cholinergic receptor, n... 50 8e-06
BC075040-1|AAH75040.1| 502|Homo sapiens cholinergic receptor, n... 50 8e-06
AL592078-3|CAI16184.1| 502|Homo sapiens cholinergic receptor, n... 50 8e-06
AJ295237-1|CAC16144.1| 450|Homo sapiens neuronal nicotinic acet... 50 8e-06
AJ278118-1|CAC20435.1| 450|Homo sapiens neuronal nicotinic acet... 50 8e-06
AJ001935-1|CAA05108.1| 504|Homo sapiens CHRNB2 protein. 50 8e-06
AF327367-1|AAK14333.1| 450|Homo sapiens nicotinic acetylcholine... 50 8e-06
AF199235-1|AAG00795.2| 450|Homo sapiens nicotinic acetylcholine... 50 8e-06
AF077186-1|AAD45422.1| 502|Homo sapiens neuronal nicotinic acet... 50 8e-06
Y00762-1|CAA68731.1| 457|Homo sapiens protein ( Human mRNA for ... 50 1e-05
X02502-1|CAA26344.1| 457|Homo sapiens acetylcholine receptor pr... 50 1e-05
S77094-1|AAD14247.1| 457|Homo sapiens nicotinic acetylcholine r... 50 1e-05
BC111802-1|AAI11803.1| 465|Homo sapiens CHRNG protein protein. 50 1e-05
BC006314-1|AAH06314.1| 269|Homo sapiens CHRNA1 protein protein. 50 1e-05
AC018890-1|AAY14687.1| 457|Homo sapiens unknown protein. 50 1e-05
DQ644022-1|ABG35128.1| 456|Homo sapiens 5-HT3 receptor subunit ... 49 3e-05
BC101185-1|AAI01186.1| 374|Homo sapiens HTR3E protein protein. 49 3e-05
BC101183-1|AAI01184.1| 471|Homo sapiens 5-hydroxytryptamine (se... 49 3e-05
BC101182-1|AAI01183.1| 471|Homo sapiens 5-hydroxytryptamine (se... 49 3e-05
AY159813-1|AAO38167.2| 471|Homo sapiens 5-hydroxytryptamine ser... 49 3e-05
S77554-1|AAB33983.1| 474|Homo sapiens GABAA receptor beta 2 sub... 48 3e-05
S77553-1|AAB33982.1| 512|Homo sapiens GABAA receptor beta 2 sub... 48 3e-05
S67368-1|AAB29370.1| 474|Homo sapiens gamma-aminobutyric acid A... 48 3e-05
BC105639-1|AAI05640.1| 474|Homo sapiens GABRB2 protein protein. 48 3e-05
BC099719-1|AAH99719.1| 474|Homo sapiens GABRB2 protein protein. 48 3e-05
BC099705-1|AAH99705.1| 474|Homo sapiens GABRB2 protein protein. 48 3e-05
BC131799-1|AAI31800.1| 447|Homo sapiens 5-hydroxytryptamine (se... 48 6e-05
AF459285-1|AAL66182.1| 447|Homo sapiens 5-hydroxytryptamine rec... 47 8e-05
BC110597-1|AAI10598.1| 411|Homo sapiens ligand-gated ion channe... 47 1e-04
BC096083-1|AAH96083.1| 198|Homo sapiens CHRNB4 protein protein. 47 1e-04
BC096081-1|AAH96081.1| 198|Homo sapiens CHRNB4 protein protein. 47 1e-04
AY349353-1|AAQ93477.1| 456|Homo sapiens 5-HT3c1 serotonin recep... 47 1e-04
AY349352-1|AAQ93476.1| 441|Homo sapiens 5-HT3c1 serotonin recep... 47 1e-04
AK122638-1|BAC85499.1| 266|Homo sapiens yte protein of 76kDa) (... 47 1e-04
AF512521-1|AAO20969.1| 411|Homo sapiens ligand-gated ion channe... 47 1e-04
X55019-1|CAA38759.1| 517|Homo sapiens acetylcholine receptor de... 46 1e-04
BC093925-1|AAH93925.1| 517|Homo sapiens cholinergic receptor, n... 46 1e-04
BC093923-1|AAH93923.1| 517|Homo sapiens cholinergic receptor, n... 46 1e-04
AC092165-2|AAY24102.1| 517|Homo sapiens unknown protein. 46 1e-04
AB223030-1|BAE19924.1| 411|Homo sapiens ligand-gated ion-channe... 46 1e-04
Z23141-1|CAA80672.1| 479|Homo sapiens cholinergic receptor, nic... 46 2e-04
Y08420-1|CAA69697.1| 502|Homo sapiens nicotinic acetylcholine r... 46 2e-04
X70297-1|CAA49778.1| 502|Homo sapiens neuronal nicotinic acetyl... 46 2e-04
U62436-1|AAB40114.1| 502|Homo sapiens nicotinic acetylcholine r... 46 2e-04
L08485-1|AAA58490.1| 462|Homo sapiens GABA-benzodiazepine recep... 46 2e-04
BT009830-1|AAP88832.1| 462|Homo sapiens gamma-aminobutyric acid... 46 2e-04
BC113422-1|AAI13423.1| 462|Homo sapiens gamma-aminobutyric acid... 46 2e-04
BC111979-1|AAI11980.1| 462|Homo sapiens gamma-aminobutyric acid... 46 2e-04
AJ586911-1|CAE52911.1| 502|Homo sapiens nicotinic acetylcholine... 46 2e-04
U40583-1|AAA83561.1| 502|Homo sapiens alpha 7 neuronal nicotini... 44 5e-04
AF385585-1|AAK68111.1| 502|Homo sapiens nicotinic cholinergic r... 44 5e-04
BC028629-1|AAH28629.1| 492|Homo sapiens gamma-aminobutyric acid... 44 0.001
S62908-1|AAB27279.1| 492|Homo sapiens gamma-aminobutyric acidA ... 43 0.001
AF166361-1|AAG12455.1| 492|Homo sapiens GABA receptor subunit a... 43 0.001
U77731-2|AAB38273.1| 360|Homo sapiens glycine receptor alpha 2B... 42 0.002
CR450343-1|CAG29339.1| 452|Homo sapiens GLRA2 protein. 42 0.002
AY437084-1|AAR87843.1| 452|Homo sapiens glycine receptor alpha2... 42 0.002
X52008-1|CAA36257.1| 452|Homo sapiens inhibitory glycine recept... 42 0.003
U77731-1|AAB38272.1| 360|Homo sapiens glycine receptor alpha 2 ... 42 0.003
M59216-1|AAA35862.1| 474|Homo sapiens gamma-aminobutyric acid r... 42 0.003
BC032864-1|AAH32864.1| 452|Homo sapiens glycine receptor, alpha... 42 0.003
AY437083-1|AAR87842.1| 452|Homo sapiens glycine receptor alpha2... 42 0.003
AF053495-1|AAC35290.1| 452|Homo sapiens glycine receptor alpha ... 42 0.003
X14767-1|CAA32875.1| 474|Homo sapiens GABA-A receptor beta 1 su... 41 0.005
S81944-1|AAB36480.1| 453|Homo sapiens gamma-aminobutyric acid t... 41 0.005
BC109211-1|AAI09212.1| 632|Homo sapiens gamma-aminobutyric acid... 41 0.005
BC109210-1|AAI09211.1| 632|Homo sapiens gamma-aminobutyric acid... 41 0.005
BC099641-1|AAH99641.1| 453|Homo sapiens gamma-aminobutyric acid... 41 0.005
BC099640-1|AAH99640.1| 453|Homo sapiens gamma-aminobutyric acid... 41 0.005
BC096242-1|AAH96242.1| 453|Homo sapiens gamma-aminobutyric acid... 41 0.005
BC096241-1|AAH96241.1| 453|Homo sapiens gamma-aminobutyric acid... 41 0.005
AF189259-1|AAF70380.1| 632|Homo sapiens GABA-A receptor theta s... 41 0.005
AF144648-1|AAD51172.1| 627|Homo sapiens GABA-A receptor theta p... 41 0.005
X52009-1|CAA36258.1| 449|Homo sapiens inhibitory glycine recept... 40 0.012
BC033801-1|AAH33801.1| 452|Homo sapiens gamma-aminobutyric acid... 40 0.012
AL391845-4|CAI15436.1| 452|Homo sapiens gamma-aminobutyric acid... 40 0.012
AF016917-1|AAB70007.1| 452|Homo sapiens GABA-A receptor delta s... 40 0.012
U30461-1|AAB52519.1| 554|Homo sapiens GABAA receptor subunit al... 39 0.020
BC035055-1|AAH35055.1| 554|Homo sapiens gamma-aminobutyric acid... 39 0.020
U95367-1|AAC51357.1| 440|Homo sapiens GABA-A receptor pi subuni... 38 0.036
BC109106-1|AAI09107.1| 440|Homo sapiens gamma-aminobutyric acid... 38 0.036
BC109105-1|AAI09106.1| 440|Homo sapiens gamma-aminobutyric acid... 38 0.036
BC074865-1|AAH74865.1| 440|Homo sapiens gamma-aminobutyric acid... 38 0.036
BC074810-1|AAH74810.1| 440|Homo sapiens gamma-aminobutyric acid... 38 0.036
AF009702-1|AAC24194.1| 440|Homo sapiens GABA-A receptor pi subu... 38 0.036
BC114947-1|AAI14948.1| 457|Homo sapiens GLRA1 protein protein. 38 0.062
BC074980-1|AAH74980.1| 449|Homo sapiens glycine receptor, alpha... 38 0.062
Z93848-1|CAI41994.1| 376|Homo sapiens glycine receptor, alpha 4... 37 0.11
BC022449-1|AAH22449.1| 474|Homo sapiens gamma-aminobutyric acid... 37 0.11
AL049610-1|CAI42158.1| 376|Homo sapiens glycine receptor, alpha... 37 0.11
U93917-1|AAC39917.1| 449|Homo sapiens glycine receptor alpha 3 ... 36 0.19
BC036086-1|AAH36086.1| 464|Homo sapiens glycine receptor, alpha... 36 0.19
AF017724-1|AAC39919.1| 465|Homo sapiens glycine receptor alpha ... 36 0.19
BC114967-1|AAI14968.1| 366|Homo sapiens GLRA1 protein protein. 35 0.44
BC146774-1|AAI46775.1| 1114|Homo sapiens GPR124 protein protein. 31 7.1
AY181242-1|AAO27354.1| 1331|Homo sapiens G protein-coupled recep... 31 7.1
AK074099-1|BAB84925.1| 1310|Homo sapiens FLJ00170 protein protein. 31 7.1
AF378755-1|AAL11992.1| 1331|Homo sapiens tumor endothelial marke... 31 7.1
AB040964-1|BAA96055.2| 1206|Homo sapiens KIAA1531 protein protein. 31 7.1
>AJ306454-1|CAC34819.1| 497|Homo sapiens neuronal nicotinic
acetylcholine receptor beta-4 subunit protein.
Length = 497
Score = 62.9 bits (146), Expect = 1e-09
Identities = 44/173 (25%), Positives = 76/173 (43%), Gaps = 8/173 (4%)
Frame = +1
Query: 88 LDAIASAAECENATSLSLMIDSLL--ATYDRESPP--DSKIVVNLTLHLRHA---NIRES 246
L A+ C A + ++D LL Y+ P S ++++ L L A ++ E
Sbjct: 12 LVALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNER 71
Query: 247 ESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALR 423
E + L+ W D RL+WN+ + G + + ++R+W PD+VL N T
Sbjct: 72 EQIMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNDGTYEVSVYTN 131
Query: 424 ARVSNNGSVSWIKRLDISTPISMQLDNWXNDMXTCTFXFGSRMHNSDXXDFVI 582
V +NGSV W+ + +++ + D CT F S ++ D V+
Sbjct: 132 LIVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRSWTYDHTEIDMVL 184
>Y08416-1|CAA69693.1| 498|Homo sapiens nicotinic acetylcholine
receptor beta4 subunit precursor protein.
Length = 498
Score = 60.9 bits (141), Expect = 6e-09
Identities = 45/174 (25%), Positives = 77/174 (44%), Gaps = 9/174 (5%)
Frame = +1
Query: 88 LDAIASAAECENATSLSLMIDSLL--ATYDRESPP--DSKIVVNLTLHLRHA---NIRES 246
L A+ C A + ++D LL Y+ P S ++++ L L A ++ E
Sbjct: 12 LVALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNER 71
Query: 247 ESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYAL 420
E + L+ W D RL+WN+ + G + + ++R+W PD+VL N A T
Sbjct: 72 EQIMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNADGTYEVSVYT 131
Query: 421 RARVSNNGSVSWIKRLDISTPISMQLDNWXNDMXTCTFXFGSRMHNSDXXDFVI 582
V +NGSV W+ + +++ + D CT F S ++ D V+
Sbjct: 132 NLIVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRSWTYDHTEIDMVL 185
>U62439-1|AAB40117.1| 498|Homo sapiens nicotinic acetylcholine
receptor beta4 subunit precursor protein.
Length = 498
Score = 60.9 bits (141), Expect = 6e-09
Identities = 45/174 (25%), Positives = 77/174 (44%), Gaps = 9/174 (5%)
Frame = +1
Query: 88 LDAIASAAECENATSLSLMIDSLL--ATYDRESPP--DSKIVVNLTLHLRHA---NIRES 246
L A+ C A + ++D LL Y+ P S ++++ L L A ++ E
Sbjct: 12 LVALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNER 71
Query: 247 ESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYAL 420
E + L+ W D RL+WN+ + G + + ++R+W PD+VL N A T
Sbjct: 72 EQIMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNADGTYEVSVYT 131
Query: 421 RARVSNNGSVSWIKRLDISTPISMQLDNWXNDMXTCTFXFGSRMHNSDXXDFVI 582
V +NGSV W+ + +++ + D CT F S ++ D V+
Sbjct: 132 NLIVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRSWTYDHTEIDMVL 185
>U48861-1|AAA92123.1| 498|Homo sapiens beta 4 nicotinic
acetylcholine receptor subunit protein.
Length = 498
Score = 60.9 bits (141), Expect = 6e-09
Identities = 45/174 (25%), Positives = 77/174 (44%), Gaps = 9/174 (5%)
Frame = +1
Query: 88 LDAIASAAECENATSLSLMIDSLL--ATYDRESPP--DSKIVVNLTLHLRHA---NIRES 246
L A+ C A + ++D LL Y+ P S ++++ L L A ++ E
Sbjct: 12 LVALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNER 71
Query: 247 ESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYAL 420
E + L+ W D RL+WN+ + G + + ++R+W PD+VL N A T
Sbjct: 72 EQIMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNADGTYEVSVYT 131
Query: 421 RARVSNNGSVSWIKRLDISTPISMQLDNWXNDMXTCTFXFGSRMHNSDXXDFVI 582
V +NGSV W+ + +++ + D CT F S ++ D V+
Sbjct: 132 NLIVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRSWTYDHTEIDMVL 185
>BC096082-1|AAH96082.1| 498|Homo sapiens cholinergic receptor,
nicotinic, beta 4 protein.
Length = 498
Score = 60.9 bits (141), Expect = 6e-09
Identities = 45/174 (25%), Positives = 77/174 (44%), Gaps = 9/174 (5%)
Frame = +1
Query: 88 LDAIASAAECENATSLSLMIDSLL--ATYDRESPP--DSKIVVNLTLHLRHA---NIRES 246
L A+ C A + ++D LL Y+ P S ++++ L L A ++ E
Sbjct: 12 LVALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNER 71
Query: 247 ESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYAL 420
E + L+ W D RL+WN+ + G + + ++R+W PD+VL N A T
Sbjct: 72 EQIMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNADGTYEVSVYT 131
Query: 421 RARVSNNGSVSWIKRLDISTPISMQLDNWXNDMXTCTFXFGSRMHNSDXXDFVI 582
V +NGSV W+ + +++ + D CT F S ++ D V+
Sbjct: 132 NLIVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRSWTYDHTEIDMVL 185
>BC096080-1|AAH96080.1| 498|Homo sapiens cholinergic receptor,
nicotinic, beta 4 protein.
Length = 498
Score = 60.9 bits (141), Expect = 6e-09
Identities = 45/174 (25%), Positives = 77/174 (44%), Gaps = 9/174 (5%)
Frame = +1
Query: 88 LDAIASAAECENATSLSLMIDSLL--ATYDRESPP--DSKIVVNLTLHLRHA---NIRES 246
L A+ C A + ++D LL Y+ P S ++++ L L A ++ E
Sbjct: 12 LVALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNER 71
Query: 247 ESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYAL 420
E + L+ W D RL+WN+ + G + + ++R+W PD+VL N A T
Sbjct: 72 EQIMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNADGTYEVSVYT 131
Query: 421 RARVSNNGSVSWIKRLDISTPISMQLDNWXNDMXTCTFXFGSRMHNSDXXDFVI 582
V +NGSV W+ + +++ + D CT F S ++ D V+
Sbjct: 132 NLIVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRSWTYDHTEIDMVL 185
>AF306329-1|AAL02062.1| 498|Homo sapiens neuronal nicotinic
acetylcholine receptor beta 4 subunit protein.
Length = 498
Score = 60.9 bits (141), Expect = 6e-09
Identities = 45/174 (25%), Positives = 77/174 (44%), Gaps = 9/174 (5%)
Frame = +1
Query: 88 LDAIASAAECENATSLSLMIDSLL--ATYDRESPP--DSKIVVNLTLHLRHA---NIRES 246
L A+ C A + ++D LL Y+ P S ++++ L L A ++ E
Sbjct: 12 LVALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNER 71
Query: 247 ESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYAL 420
E + L+ W D RL+WN+ + G + + ++R+W PD+VL N A T
Sbjct: 72 EQIMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNADGTYEVSVYT 131
Query: 421 RARVSNNGSVSWIKRLDISTPISMQLDNWXNDMXTCTFXFGSRMHNSDXXDFVI 582
V +NGSV W+ + +++ + D CT F S ++ D V+
Sbjct: 132 NLIVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRSWTYDHTEIDMVL 185
>Y08417-1|CAA69694.1| 458|Homo sapiens nicotinic acetylcholine
receptor beta3 subunit precursor protein.
Length = 458
Score = 58.8 bits (136), Expect = 2e-08
Identities = 31/105 (29%), Positives = 49/105 (46%), Gaps = 2/105 (1%)
Frame = +1
Query: 274 LQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLL-NAAATTAGDYALRARVSNNGS 447
L+ W D +L WN ++G + V SE LW PD+VL NA G + V +NG+
Sbjct: 81 LKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFEGSLMTKVIVKSNGT 140
Query: 448 VSWIKRLDISTPISMQLDNWXNDMXTCTFXFGSRMHNSDXXDFVI 582
V W + +M + + D C+ FGS ++ D ++
Sbjct: 141 VVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGTMVDLIL 185
>X67513-1|CAA47851.1| 423|Homo sapiens nicotinic acetylcholine
receptor beta-3 subunit protein.
Length = 423
Score = 58.8 bits (136), Expect = 2e-08
Identities = 31/105 (29%), Positives = 49/105 (46%), Gaps = 2/105 (1%)
Frame = +1
Query: 274 LQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLL-NAAATTAGDYALRARVSNNGS 447
L+ W D +L WN ++G + V SE LW PD+VL NA G + V +NG+
Sbjct: 46 LKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFEGSLMTKVIVKSNGT 105
Query: 448 VSWIKRLDISTPISMQLDNWXNDMXTCTFXFGSRMHNSDXXDFVI 582
V W + +M + + D C+ FGS ++ D ++
Sbjct: 106 VVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGTMVDLIL 150
>U62438-1|AAB40116.1| 458|Homo sapiens nicotinic acetylcholine
receptor beta3 subunit precursor protein.
Length = 458
Score = 58.8 bits (136), Expect = 2e-08
Identities = 31/105 (29%), Positives = 49/105 (46%), Gaps = 2/105 (1%)
Frame = +1
Query: 274 LQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLL-NAAATTAGDYALRARVSNNGS 447
L+ W D +L WN ++G + V SE LW PD+VL NA G + V +NG+
Sbjct: 81 LKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFEGSLMTKVIVKSNGT 140
Query: 448 VSWIKRLDISTPISMQLDNWXNDMXTCTFXFGSRMHNSDXXDFVI 582
V W + +M + + D C+ FGS ++ D ++
Sbjct: 141 VVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGTMVDLIL 185
>BC069788-1|AAH69788.1| 458|Homo sapiens cholinergic receptor,
nicotinic, beta 3 protein.
Length = 458
Score = 58.8 bits (136), Expect = 2e-08
Identities = 31/105 (29%), Positives = 49/105 (46%), Gaps = 2/105 (1%)
Frame = +1
Query: 274 LQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLL-NAAATTAGDYALRARVSNNGS 447
L+ W D +L WN ++G + V SE LW PD+VL NA G + V +NG+
Sbjct: 81 LKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFEGSLMTKVIVKSNGT 140
Query: 448 VSWIKRLDISTPISMQLDNWXNDMXTCTFXFGSRMHNSDXXDFVI 582
V W + +M + + D C+ FGS ++ D ++
Sbjct: 141 VVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGTMVDLIL 185
>BC069703-1|AAH69703.1| 458|Homo sapiens cholinergic receptor,
nicotinic, beta 3 protein.
Length = 458
Score = 58.8 bits (136), Expect = 2e-08
Identities = 31/105 (29%), Positives = 49/105 (46%), Gaps = 2/105 (1%)
Frame = +1
Query: 274 LQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLL-NAAATTAGDYALRARVSNNGS 447
L+ W D +L WN ++G + V SE LW PD+VL NA G + V +NG+
Sbjct: 81 LKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFEGSLMTKVIVKSNGT 140
Query: 448 VSWIKRLDISTPISMQLDNWXNDMXTCTFXFGSRMHNSDXXDFVI 582
V W + +M + + D C+ FGS ++ D ++
Sbjct: 141 VVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGTMVDLIL 185
>BC069681-1|AAH69681.1| 458|Homo sapiens cholinergic receptor,
nicotinic, beta 3 protein.
Length = 458
Score = 58.8 bits (136), Expect = 2e-08
Identities = 31/105 (29%), Positives = 49/105 (46%), Gaps = 2/105 (1%)
Frame = +1
Query: 274 LQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLL-NAAATTAGDYALRARVSNNGS 447
L+ W D +L WN ++G + V SE LW PD+VL NA G + V +NG+
Sbjct: 81 LKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFEGSLMTKVIVKSNGT 140
Query: 448 VSWIKRLDISTPISMQLDNWXNDMXTCTFXFGSRMHNSDXXDFVI 582
V W + +M + + D C+ FGS ++ D ++
Sbjct: 141 VVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGTMVDLIL 185
>AF140765-1|AAD33063.1| 458|Homo sapiens neuronal acetylcholine
receptor beta-3 subunit precursor protein.
Length = 458
Score = 58.8 bits (136), Expect = 2e-08
Identities = 31/105 (29%), Positives = 49/105 (46%), Gaps = 2/105 (1%)
Frame = +1
Query: 274 LQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLL-NAAATTAGDYALRARVSNNGS 447
L+ W D +L WN ++G + V SE LW PD+VL NA G + V +NG+
Sbjct: 81 LKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFEGSLMTKVIVKSNGT 140
Query: 448 VSWIKRLDISTPISMQLDNWXNDMXTCTFXFGSRMHNSDXXDFVI 582
V W + +M + + D C+ FGS ++ D ++
Sbjct: 141 VVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGTMVDLIL 185
>Y08419-1|CAA69696.1| 468|Homo sapiens nicotinic acetylcholine
receptor alpha5 subunit precursor protein.
Length = 468
Score = 58.0 bits (134), Expect = 4e-08
Identities = 37/174 (21%), Positives = 75/174 (43%), Gaps = 9/174 (5%)
Frame = +1
Query: 142 MIDSLLATYDRESPP----DSKIVVNLTLHLRH-ANIRESESTVRILADLQMNWIDKRLS 306
++ L Y+R P + KI + L + ++ E + L+ WID +L
Sbjct: 50 LLKDLFQDYERWVRPVEHLNDKIKIKFGLAISQLVDVDEKNQLMTTNVWLKQEWIDVKLR 109
Query: 307 WNAGEWG-CSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVSWIKRLDISTP 483
WN ++G V S+ +W PD+VL + A + + + NG+V+W + +
Sbjct: 110 WNPDDYGGIKVIRVPSDSVWTPDIVLFDNADGRFEGTSTKTVIRYNGTVTWTPPANYKSS 169
Query: 484 ISMQLDNWXNDMXTCTFXFGSRMHNSDXXDFVI---DXXIYXMFXSXAWDVTGS 636
++ + + D+ C+ FGS ++ D ++ D F + W++ +
Sbjct: 170 CTIDVTFFPFDLQNCSMKFGSWTYDGSQVDIILEDQDVDKRDFFDNGEWEIVSA 223
>U62434-1|AAB40112.1| 468|Homo sapiens nicotinic acetylcholine
receptor alpha5 subunit precursor protein.
Length = 468
Score = 58.0 bits (134), Expect = 4e-08
Identities = 37/174 (21%), Positives = 75/174 (43%), Gaps = 9/174 (5%)
Frame = +1
Query: 142 MIDSLLATYDRESPP----DSKIVVNLTLHLRH-ANIRESESTVRILADLQMNWIDKRLS 306
++ L Y+R P + KI + L + ++ E + L+ WID +L
Sbjct: 50 LLKDLFQDYERWVRPVEHLNDKIKIKFGLAISQLVDVDEKNQLMTTNVWLKQEWIDVKLR 109
Query: 307 WNAGEWG-CSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVSWIKRLDISTP 483
WN ++G V S+ +W PD+VL + A + + + NG+V+W + +
Sbjct: 110 WNPDDYGGIKVIRVPSDSVWTPDIVLFDNADGRFEGTSTKTVIRYNGTVTWTPPANYKSS 169
Query: 484 ISMQLDNWXNDMXTCTFXFGSRMHNSDXXDFVI---DXXIYXMFXSXAWDVTGS 636
++ + + D+ C+ FGS ++ D ++ D F + W++ +
Sbjct: 170 CTIDVTFFPFDLQNCSMKFGSWTYDGSQVDIILEDQDVDKRDFFDNGEWEIVSA 223
>BC033639-1|AAH33639.1| 468|Homo sapiens cholinergic receptor,
nicotinic, alpha 5 protein.
Length = 468
Score = 58.0 bits (134), Expect = 4e-08
Identities = 37/174 (21%), Positives = 75/174 (43%), Gaps = 9/174 (5%)
Frame = +1
Query: 142 MIDSLLATYDRESPP----DSKIVVNLTLHLRH-ANIRESESTVRILADLQMNWIDKRLS 306
++ L Y+R P + KI + L + ++ E + L+ WID +L
Sbjct: 50 LLKDLFQDYERWVRPVEHLNDKIKIKFGLAISQLVDVDEKNQLMTTNVWLKQEWIDVKLR 109
Query: 307 WNAGEWG-CSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVSWIKRLDISTP 483
WN ++G V S+ +W PD+VL + A + + + NG+V+W + +
Sbjct: 110 WNPDDYGGIKVIRVPSDSVWTPDIVLFDNADGRFEGTSTKTVIRYNGTVTWTPPANYKSS 169
Query: 484 ISMQLDNWXNDMXTCTFXFGSRMHNSDXXDFVI---DXXIYXMFXSXAWDVTGS 636
++ + + D+ C+ FGS ++ D ++ D F + W++ +
Sbjct: 170 CTIDVTFFPFDLQNCSMKFGSWTYDGSQVDIILEDQDVDKRDFFDNGEWEIVSA 223
>AJ306481-1|CAC34820.1| 468|Homo sapiens neuronal nicotinic
acetylcholine receptor alpha-5subunit protein.
Length = 468
Score = 58.0 bits (134), Expect = 4e-08
Identities = 37/174 (21%), Positives = 75/174 (43%), Gaps = 9/174 (5%)
Frame = +1
Query: 142 MIDSLLATYDRESPP----DSKIVVNLTLHLRH-ANIRESESTVRILADLQMNWIDKRLS 306
++ L Y+R P + KI + L + ++ E + L+ WID +L
Sbjct: 50 LLKDLFQDYERWVRPVEHLNDKIKIKFGLAISQLVDVDEKNQLMTTNVWLKQEWIDVKLR 109
Query: 307 WNAGEWG-CSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVSWIKRLDISTP 483
WN ++G V S+ +W PD+VL + A + + + NG+V+W + +
Sbjct: 110 WNPDDYGGIKVIRVPSDSVWTPDIVLFDNADGRFEGTSTKTVIRYNGTVTWTPPANYKSS 169
Query: 484 ISMQLDNWXNDMXTCTFXFGSRMHNSDXXDFVI---DXXIYXMFXSXAWDVTGS 636
++ + + D+ C+ FGS ++ D ++ D F + W++ +
Sbjct: 170 CTIDVTFFPFDLQNCSMKFGSWTYDGSQVDIILEDQDVDKRDFFDNGEWEIVSA 223
>X14830-1|CAA32939.1| 501|Homo sapiens protein ( Human mRNA for
muscle acetylcholine receptor beta-subunit. ).
Length = 501
Score = 57.2 bits (132), Expect = 7e-08
Identities = 44/134 (32%), Positives = 66/134 (49%), Gaps = 4/134 (2%)
Frame = +1
Query: 172 RESPPDSKIVVNLTL-HLRHANIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLV 345
RE ++ V L L L N ++ E + ++ DL+ W D RLSW+ E G + +
Sbjct: 46 REVGDRVRVSVGLILAQLISLNEKDEEMSTKVYLDLE--WTDYRLSWDPAEHDGIDSLRI 103
Query: 346 SSERLWRPDVVLLNAAATTAGDYAL--RARVSNNGSVSWIKRLDISTPISMQLDNWXNDM 519
++E +W PDVVLLN D AL VS++GSV W + S+Q+ + D
Sbjct: 104 TAESVWLPDVVLLNNNDGNF-DVALDISVVVSSDGSVRWQPPGIYRSSCSIQVTYFPFDW 162
Query: 520 XTCTFXFGSRMHNS 561
CT F S ++S
Sbjct: 163 QNCTMVFSSYSYDS 176
>BC011371-1|AAH11371.1| 501|Homo sapiens cholinergic receptor,
nicotinic, beta 1 (muscle) protein.
Length = 501
Score = 57.2 bits (132), Expect = 7e-08
Identities = 44/134 (32%), Positives = 66/134 (49%), Gaps = 4/134 (2%)
Frame = +1
Query: 172 RESPPDSKIVVNLTL-HLRHANIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLV 345
RE ++ V L L L N ++ E + ++ DL+ W D RLSW+ E G + +
Sbjct: 46 REVGDRVRVSVGLILAQLISLNEKDEEMSTKVYLDLE--WTDYRLSWDPAEHDGIDSLRI 103
Query: 346 SSERLWRPDVVLLNAAATTAGDYAL--RARVSNNGSVSWIKRLDISTPISMQLDNWXNDM 519
++E +W PDVVLLN D AL VS++GSV W + S+Q+ + D
Sbjct: 104 TAESVWLPDVVLLNNNDGNF-DVALDISVVVSSDGSVRWQPPGIYRSSCSIQVTYFPFDW 162
Query: 520 XTCTFXFGSRMHNS 561
CT F S ++S
Sbjct: 163 QNCTMVFSSYSYDS 176
>Y08418-1|CAA69695.1| 503|Homo sapiens nicotinic acetylcholine
receptor alpha3 subunit precursor protein.
Length = 503
Score = 56.8 bits (131), Expect = 9e-08
Identities = 29/105 (27%), Positives = 52/105 (49%), Gaps = 2/105 (1%)
Frame = +1
Query: 274 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 447
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 85 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 144
Query: 448 VSWIKRLDISTPISMQLDNWXNDMXTCTFXFGSRMHNSDXXDFVI 582
V+WI + + + + D CT FGS ++ D V+
Sbjct: 145 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVL 189
>X53559-1|CAA37625.1| 474|Homo sapiens neuronal nicotinic
acetylcholine receptor alpha-3merase protein.
Length = 474
Score = 56.8 bits (131), Expect = 9e-08
Identities = 29/105 (27%), Positives = 52/105 (49%), Gaps = 2/105 (1%)
Frame = +1
Query: 274 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 447
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 56 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 115
Query: 448 VSWIKRLDISTPISMQLDNWXNDMXTCTFXFGSRMHNSDXXDFVI 582
V+WI + + + + D CT FGS ++ D V+
Sbjct: 116 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVL 160
>U62432-1|AAB40110.1| 504|Homo sapiens nicotinic acetylcholine
receptor alpha3 subunit precursor protein.
Length = 504
Score = 56.8 bits (131), Expect = 9e-08
Identities = 29/105 (27%), Positives = 52/105 (49%), Gaps = 2/105 (1%)
Frame = +1
Query: 274 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 447
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 86 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 145
Query: 448 VSWIKRLDISTPISMQLDNWXNDMXTCTFXFGSRMHNSDXXDFVI 582
V+WI + + + + D CT FGS ++ D V+
Sbjct: 146 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVL 190
>M83712-1|AAA58357.1| 468|Homo sapiens nicotinic receptor alpha 5
subunit protein.
Length = 468
Score = 56.8 bits (131), Expect = 9e-08
Identities = 37/174 (21%), Positives = 74/174 (42%), Gaps = 9/174 (5%)
Frame = +1
Query: 142 MIDSLLATYDRESPP----DSKIVVNLTLHLRH-ANIRESESTVRILADLQMNWIDKRLS 306
++ L Y+R P + KI + L + ++ E + L+ WID +L
Sbjct: 50 LLKDLFQDYERWVRPVEHLNDKIKIKFGLAISQLVDVDEKNQLMTTNVWLKQEWIDVKLR 109
Query: 307 WNAGEWG-CSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVSWIKRLDISTP 483
WN ++G V S+ W PD+VL + A + + + NG+V+W + +
Sbjct: 110 WNPDDYGGIKVIRVPSDSSWTPDIVLFDNADGRFEGTSTKTVIRYNGTVTWTPPANYKSS 169
Query: 484 ISMQLDNWXNDMXTCTFXFGSRMHNSDXXDFVI---DXXIYXMFXSXAWDVTGS 636
++ + + D+ C+ FGS ++ D ++ D F + W++ +
Sbjct: 170 CTIDVTFFPFDLQNCSMKFGSWTYDGSQVDIILEDQDVDKRDFFDNGEWEIVSA 223
>M37981-1|AAA59942.1| 503|Homo sapiens neuronal nicotinic
acetylcholine receptor protein.
Length = 503
Score = 56.8 bits (131), Expect = 9e-08
Identities = 29/105 (27%), Positives = 52/105 (49%), Gaps = 2/105 (1%)
Frame = +1
Query: 274 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 447
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 85 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 144
Query: 448 VSWIKRLDISTPISMQLDNWXNDMXTCTFXFGSRMHNSDXXDFVI 582
V+WI + + + + D CT FGS ++ D V+
Sbjct: 145 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVL 189
>BT006897-1|AAP35543.1| 505|Homo sapiens cholinergic receptor,
nicotinic, alpha polypeptide 3 protein.
Length = 505
Score = 56.8 bits (131), Expect = 9e-08
Identities = 29/105 (27%), Positives = 52/105 (49%), Gaps = 2/105 (1%)
Frame = +1
Query: 274 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 447
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 87 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 146
Query: 448 VSWIKRLDISTPISMQLDNWXNDMXTCTFXFGSRMHNSDXXDFVI 582
V+WI + + + + D CT FGS ++ D V+
Sbjct: 147 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVL 191
>BT006646-1|AAP35292.1| 489|Homo sapiens cholinergic receptor,
nicotinic, alpha polypeptide 3 protein.
Length = 489
Score = 56.8 bits (131), Expect = 9e-08
Identities = 29/105 (27%), Positives = 52/105 (49%), Gaps = 2/105 (1%)
Frame = +1
Query: 274 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 447
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 87 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 146
Query: 448 VSWIKRLDISTPISMQLDNWXNDMXTCTFXFGSRMHNSDXXDFVI 582
V+WI + + + + D CT FGS ++ D V+
Sbjct: 147 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVL 191
>BC098443-1|AAH98443.1| 504|Homo sapiens cholinergic receptor,
nicotinic, alpha 3 protein.
Length = 504
Score = 56.8 bits (131), Expect = 9e-08
Identities = 29/105 (27%), Positives = 52/105 (49%), Gaps = 2/105 (1%)
Frame = +1
Query: 274 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 447
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 86 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 145
Query: 448 VSWIKRLDISTPISMQLDNWXNDMXTCTFXFGSRMHNSDXXDFVI 582
V+WI + + + + D CT FGS ++ D V+
Sbjct: 146 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVL 190
>BC006114-1|AAH06114.1| 489|Homo sapiens CHRNA3 protein protein.
Length = 489
Score = 56.8 bits (131), Expect = 9e-08
Identities = 29/105 (27%), Positives = 52/105 (49%), Gaps = 2/105 (1%)
Frame = +1
Query: 274 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 447
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 87 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 146
Query: 448 VSWIKRLDISTPISMQLDNWXNDMXTCTFXFGSRMHNSDXXDFVI 582
V+WI + + + + D CT FGS ++ D V+
Sbjct: 147 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVL 191
>BC002996-1|AAH02996.1| 505|Homo sapiens cholinergic receptor,
nicotinic, alpha 3 protein.
Length = 505
Score = 56.8 bits (131), Expect = 9e-08
Identities = 29/105 (27%), Positives = 52/105 (49%), Gaps = 2/105 (1%)
Frame = +1
Query: 274 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 447
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 87 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 146
Query: 448 VSWIKRLDISTPISMQLDNWXNDMXTCTFXFGSRMHNSDXXDFVI 582
V+WI + + + + D CT FGS ++ D V+
Sbjct: 147 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVL 191
>BC001642-1|AAH01642.1| 505|Homo sapiens cholinergic receptor,
nicotinic, alpha 3 protein.
Length = 505
Score = 56.8 bits (131), Expect = 9e-08
Identities = 29/105 (27%), Positives = 52/105 (49%), Gaps = 2/105 (1%)
Frame = +1
Query: 274 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 447
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 87 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 146
Query: 448 VSWIKRLDISTPISMQLDNWXNDMXTCTFXFGSRMHNSDXXDFVI 582
V+WI + + + + D CT FGS ++ D V+
Sbjct: 147 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVL 191
>BC000513-1|AAH00513.1| 505|Homo sapiens cholinergic receptor,
nicotinic, alpha 3 protein.
Length = 505
Score = 56.8 bits (131), Expect = 9e-08
Identities = 29/105 (27%), Positives = 52/105 (49%), Gaps = 2/105 (1%)
Frame = +1
Query: 274 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 447
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 87 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 146
Query: 448 VSWIKRLDISTPISMQLDNWXNDMXTCTFXFGSRMHNSDXXDFVI 582
V+WI + + + + D CT FGS ++ D V+
Sbjct: 147 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVL 191
>AJ007783-1|CAA07682.1| 504|Homo sapiens nicotinic acetylcholine
receptor alpha-3 subunit protein.
Length = 504
Score = 56.8 bits (131), Expect = 9e-08
Identities = 29/105 (27%), Positives = 52/105 (49%), Gaps = 2/105 (1%)
Frame = +1
Query: 274 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 447
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 86 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 145
Query: 448 VSWIKRLDISTPISMQLDNWXNDMXTCTFXFGSRMHNSDXXDFVI 582
V+WI + + + + D CT FGS ++ D V+
Sbjct: 146 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVL 190
>AF385584-1|AAK68110.1| 489|Homo sapiens nicotinic cholinergic
receptor alpha 3 protein.
Length = 489
Score = 56.8 bits (131), Expect = 9e-08
Identities = 29/105 (27%), Positives = 52/105 (49%), Gaps = 2/105 (1%)
Frame = +1
Query: 274 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 447
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 81 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 140
Query: 448 VSWIKRLDISTPISMQLDNWXNDMXTCTFXFGSRMHNSDXXDFVI 582
V+WI + + + + D CT FGS ++ D V+
Sbjct: 141 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVL 185
>X68275-1|CAA48336.1| 451|Homo sapiens nicotinic receptor beta 4
subunit protein.
Length = 451
Score = 56.4 bits (130), Expect = 1e-07
Identities = 35/132 (26%), Positives = 60/132 (45%), Gaps = 3/132 (2%)
Frame = +1
Query: 196 IVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 369
I + L L L ++ E + + L+ W D RL+WN+ + G + + ++R+W P
Sbjct: 7 ISIKLQLSLAQLISVNERDEIMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLP 66
Query: 370 DVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWXNDMXTCTFXFGS 546
D+VL N A T V +NGSV W+ + +++ + D CT F S
Sbjct: 67 DIVLYNNADGTYEVSVYTNLIVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRS 126
Query: 547 RMHNSDXXDFVI 582
++ D V+
Sbjct: 127 WTYDHTEIDMVL 138
>BC023553-1|AAH23553.1| 501|Homo sapiens cholinergic receptor,
nicotinic, beta 1 (muscle) protein.
Length = 501
Score = 56.0 bits (129), Expect = 2e-07
Identities = 42/136 (30%), Positives = 67/136 (49%), Gaps = 6/136 (4%)
Frame = +1
Query: 172 RESPPDSKIVVNLTL-HLRHANIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLV 345
RE ++ V L L L N ++ E + ++ DL+ W D RLSW+ E G + +
Sbjct: 46 REVGDRVRVSVGLILAQLISLNEKDEEMSTKVYLDLE--WTDYRLSWDPAEHDGIDSLRI 103
Query: 346 SSERLWRPDVVLLNAAATTAGDY----ALRARVSNNGSVSWIKRLDISTPISMQLDNWXN 513
++E +W PDVVLLN G++ + VS++GSV W + S+Q+ +
Sbjct: 104 TAESVWLPDVVLLN---NNDGNFYVALDISVVVSSDGSVRWQPPGIYRSSCSIQVTYFPF 160
Query: 514 DMXTCTFXFGSRMHNS 561
D CT F S ++S
Sbjct: 161 DWQNCTMVFSSYSYDS 176
>X66403-1|CAA47030.1| 493|Homo sapiens acetylcholine receptor
epsilon subunit CHRNE protein.
Length = 493
Score = 55.2 bits (127), Expect = 3e-07
Identities = 33/134 (24%), Positives = 67/134 (50%), Gaps = 3/134 (2%)
Frame = +1
Query: 184 PDSKIVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEWG-CSTWLVSSER 357
P+ + ++L + L + ++ E E T+ + ++W D RL+++ ++G T V SE
Sbjct: 45 PEDTVTISLKVTLTNLISLNEKEETLTTSVWIGIDWQDYRLNYSKDDFGGIETLRVPSEL 104
Query: 358 LWRPDVVLLNAAATTAG-DYALRARVSNNGSVSWIKRLDISTPISMQLDNWXNDMXTCTF 534
+W P++VL N G Y V GSV+W+ + ++++ + D C+
Sbjct: 105 VWLPEIVLENNIDGQFGVAYDANVLVYEGGSVTWLPPAIYRSVCAVEVTYFPFDWQNCSL 164
Query: 535 XFGSRMHNSDXXDF 576
F S+ +N++ +F
Sbjct: 165 IFRSQTYNAEEVEF 178
>AF105999-1|AAD24503.1| 493|Homo sapiens acetylcholine receptor
epsilon subunit protein.
Length = 493
Score = 55.2 bits (127), Expect = 3e-07
Identities = 33/134 (24%), Positives = 67/134 (50%), Gaps = 3/134 (2%)
Frame = +1
Query: 184 PDSKIVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEWG-CSTWLVSSER 357
P+ + ++L + L + ++ E E T+ + ++W D RL+++ ++G T V SE
Sbjct: 45 PEDTVTISLKVTLTNLISLNEKEETLTTSVWIGIDWQDYRLNYSKDDFGGIETLRVPSEL 104
Query: 358 LWRPDVVLLNAAATTAG-DYALRARVSNNGSVSWIKRLDISTPISMQLDNWXNDMXTCTF 534
+W P++VL N G Y V GSV+W+ + ++++ + D C+
Sbjct: 105 VWLPEIVLENNIDGQFGVAYDANVLVYEGGSVTWLPPAIYRSVCAVEVTYFPFDWQNCSL 164
Query: 535 XFGSRMHNSDXXDF 576
F S+ +N++ +F
Sbjct: 165 IFRSQTYNAEEVEF 178
>Y16282-1|CAA76155.1| 494|Homo sapiens nicotinic acetylcholine
receptor alpha6 subunit precursor protein.
Length = 494
Score = 54.4 bits (125), Expect = 5e-07
Identities = 39/166 (23%), Positives = 73/166 (43%), Gaps = 10/166 (6%)
Frame = +1
Query: 115 CENATSLSLMIDSLLATYDRESPPDSKIVVNLTLHL-----RHANIRESESTVRILADLQ 279
C + + L + Y++ P + +T+H + AN+ E + L+
Sbjct: 28 CVGCATEERLFHKLFSHYNQFIRPVENVSDPVTVHFEVAITQLANVDEVNQIMETNLWLR 87
Query: 280 MNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNG 444
W D +L W+ E+ G T V ++++W+PD+VL N A GD+ + +A + NG
Sbjct: 88 HIWNDYKLRWDPMEYDGIETLRVPADKIWKPDIVLYNNA---VGDFQVEGKTKALLKYNG 144
Query: 445 SVSWIKRLDISTPISMQLDNWXNDMXTCTFXFGSRMHNSDXXDFVI 582
++W + M + + D C+ FGS ++ D +I
Sbjct: 145 MITWTPPAIFKSSCPMDITFFPFDHQNCSLKFGSWTYDKAEIDLLI 190
>Y16281-1|CAA76154.1| 529|Homo sapiens nicotinic acetylcholine
receptor alpha2 subunit precursor protein.
Length = 529
Score = 54.4 bits (125), Expect = 5e-07
Identities = 31/102 (30%), Positives = 49/102 (48%), Gaps = 2/102 (1%)
Frame = +1
Query: 274 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAA-ATTAGDYALRARVSNNGS 447
L+ W D +L WN ++G T L V SE +W PD+VL N A A + +A + + G+
Sbjct: 111 LKQEWSDYKLRWNPADFGNITSLRVPSEMIWIPDIVLYNNADGEFAVTHMTKAHLFSTGT 170
Query: 448 VSWIKRLDISTPISMQLDNWXNDMXTCTFXFGSRMHNSDXXD 573
V W+ + S+ + + D C FGS ++ D
Sbjct: 171 VHWVPPAIYKSSCSIDVTFFPFDQQNCKMKFGSWTYDKAKID 212
>U62435-1|AAB40113.1| 494|Homo sapiens nicotinic acetylcholine
receptor alpha6 subunit precursor protein.
Length = 494
Score = 54.4 bits (125), Expect = 5e-07
Identities = 39/166 (23%), Positives = 73/166 (43%), Gaps = 10/166 (6%)
Frame = +1
Query: 115 CENATSLSLMIDSLLATYDRESPPDSKIVVNLTLHL-----RHANIRESESTVRILADLQ 279
C + + L + Y++ P + +T+H + AN+ E + L+
Sbjct: 28 CVGCATEERLFHKLFSHYNQFIRPVENVSDPVTVHFEVAITQLANVDEVNQIMETNLWLR 87
Query: 280 MNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNG 444
W D +L W+ E+ G T V ++++W+PD+VL N A GD+ + +A + NG
Sbjct: 88 HIWNDYKLRWDPMEYDGIETLRVPADKIWKPDIVLYNNA---VGDFQVEGKTKALLKYNG 144
Query: 445 SVSWIKRLDISTPISMQLDNWXNDMXTCTFXFGSRMHNSDXXDFVI 582
++W + M + + D C+ FGS ++ D +I
Sbjct: 145 MITWTPPAIFKSSCPMDITFFPFDHQNCSLKFGSWTYDKAEIDLLI 190
>U62431-1|AAB40109.1| 529|Homo sapiens nicotinic acetylcholine
receptor alpha2 subunit precursor protein.
Length = 529
Score = 54.4 bits (125), Expect = 5e-07
Identities = 31/102 (30%), Positives = 49/102 (48%), Gaps = 2/102 (1%)
Frame = +1
Query: 274 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAA-ATTAGDYALRARVSNNGS 447
L+ W D +L WN ++G T L V SE +W PD+VL N A A + +A + + G+
Sbjct: 111 LKQEWSDYKLRWNPADFGNITSLRVPSEMIWIPDIVLYNNADGEFAVTHMTKAHLFSTGT 170
Query: 448 VSWIKRLDISTPISMQLDNWXNDMXTCTFXFGSRMHNSDXXD 573
V W+ + S+ + + D C FGS ++ D
Sbjct: 171 VHWVPPAIYKSSCSIDVTFFPFDQQNCKMKFGSWTYDKAKID 212
>M86383-1|AAC84176.1| 502|Homo sapiens nicotinic acetylcholine
receptor alpha 3 subunit precursor protein.
Length = 502
Score = 54.4 bits (125), Expect = 5e-07
Identities = 30/108 (27%), Positives = 54/108 (50%), Gaps = 5/108 (4%)
Frame = +1
Query: 274 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYAL----RARVSN 438
L+ W D +L WN +G + ++ V ++++W+PD+VL N A GD+ + +A +
Sbjct: 84 LKQIWNDYKLKWNPSGYGGAEFMRVPAQKIWKPDIVLYNNA---VGDFQVTTKTKALLKY 140
Query: 439 NGSVSWIKRLDISTPISMQLDNWXNDMXTCTFXFGSRMHNSDXXDFVI 582
G V+WI + + + + D CT FGS ++ D V+
Sbjct: 141 TGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVL 188
>BC014456-1|AAH14456.1| 494|Homo sapiens cholinergic receptor,
nicotinic, alpha 6 protein.
Length = 494
Score = 54.4 bits (125), Expect = 5e-07
Identities = 39/166 (23%), Positives = 73/166 (43%), Gaps = 10/166 (6%)
Frame = +1
Query: 115 CENATSLSLMIDSLLATYDRESPPDSKIVVNLTLHL-----RHANIRESESTVRILADLQ 279
C + + L + Y++ P + +T+H + AN+ E + L+
Sbjct: 28 CVGCATEERLFHKLFSHYNQFIRPVENVSDPVTVHFEVAITQLANVDEVNQIMETNLWLR 87
Query: 280 MNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNG 444
W D +L W+ E+ G T V ++++W+PD+VL N A GD+ + +A + NG
Sbjct: 88 HIWNDYKLRWDPMEYDGIETLRVPADKIWKPDIVLYNNA---VGDFQVEGKTKALLKYNG 144
Query: 445 SVSWIKRLDISTPISMQLDNWXNDMXTCTFXFGSRMHNSDXXDFVI 582
++W + M + + D C+ FGS ++ D +I
Sbjct: 145 MITWTPPAIFKSSCPMDITFFPFDHQNCSLKFGSWTYDKAEIDLLI 190
>AB079251-1|BAC06855.1| 494|Homo sapiens Nicotinic acetylcholine
receptor alpha 6 protein.
Length = 494
Score = 54.4 bits (125), Expect = 5e-07
Identities = 39/166 (23%), Positives = 73/166 (43%), Gaps = 10/166 (6%)
Frame = +1
Query: 115 CENATSLSLMIDSLLATYDRESPPDSKIVVNLTLHL-----RHANIRESESTVRILADLQ 279
C + + L + Y++ P + +T+H + AN+ E + L+
Sbjct: 28 CVGCATEERLFHKLFSHYNQFIRPVENVSDPVTVHFEVAITQLANVDEVNQIMETNLWLR 87
Query: 280 MNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNG 444
W D +L W+ E+ G T V ++++W+PD+VL N A GD+ + +A + NG
Sbjct: 88 HIWNDYKLRWDPMEYDGIETLRVPADKIWKPDIVLYNNA---VGDFQVEGKTKALLKYNG 144
Query: 445 SVSWIKRLDISTPISMQLDNWXNDMXTCTFXFGSRMHNSDXXDFVI 582
++W + M + + D C+ FGS ++ D +I
Sbjct: 145 MITWTPPAIFKSSCPMDITFFPFDHQNCSLKFGSWTYDKAEIDLLI 190
>Y08421-1|CAA69698.1| 627|Homo sapiens nicotinic acetylcholine
receptor alpha4 subunit precursor protein.
Length = 627
Score = 53.2 bits (122), Expect = 1e-06
Identities = 40/156 (25%), Positives = 75/156 (48%), Gaps = 10/156 (6%)
Frame = +1
Query: 142 MIDSLLATYDRESPPDSKI--VVNLTLHLRHANIRESESTVRILAD---LQMNWIDKRLS 306
++ L + Y++ S P + I VV + L A + + + +++ ++ W D +L
Sbjct: 40 LLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLR 99
Query: 307 WNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNGSVSWIKRLD 471
W+ ++ T + + SE +WRPD+VL N A GD+A+ +A + ++G V W
Sbjct: 100 WDPADYENVTSIRIPSELIWRPDIVLYNNAD---GDFAVTHLTKAHLFHDGRVQWTPPAI 156
Query: 472 ISTPISMQLDNWXNDMXTCTFXFGSRMHNSDXXDFV 579
+ S+ + + D CT FGS ++ D V
Sbjct: 157 YKSSCSIDVTFFPFDQQNCTMKFGSWTYDKAKIDLV 192
>X89741-1|CAA61893.1| 627|Homo sapiens neuronal acetylcholine
receptor alpha-4 subunit protein.
Length = 627
Score = 53.2 bits (122), Expect = 1e-06
Identities = 40/156 (25%), Positives = 75/156 (48%), Gaps = 10/156 (6%)
Frame = +1
Query: 142 MIDSLLATYDRESPPDSKI--VVNLTLHLRHANIRESESTVRILAD---LQMNWIDKRLS 306
++ L + Y++ S P + I VV + L A + + + +++ ++ W D +L
Sbjct: 40 LLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLR 99
Query: 307 WNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNGSVSWIKRLD 471
W+ ++ T + + SE +WRPD+VL N A GD+A+ +A + ++G V W
Sbjct: 100 WDPADYENVTSIRIPSELIWRPDIVLYNNAD---GDFAVTHLTKAHLFHDGRVQWTPPAI 156
Query: 472 ISTPISMQLDNWXNDMXTCTFXFGSRMHNSDXXDFV 579
+ S+ + + D CT FGS ++ D V
Sbjct: 157 YKSSCSIDVTFFPFDQQNCTMKFGSWTYDKAKIDLV 192
>X87629-1|CAA60959.1| 602|Homo sapiens nicotinic acetylcholine
receptor protein.
Length = 602
Score = 53.2 bits (122), Expect = 1e-06
Identities = 40/156 (25%), Positives = 75/156 (48%), Gaps = 10/156 (6%)
Frame = +1
Query: 142 MIDSLLATYDRESPPDSKI--VVNLTLHLRHANIRESESTVRILAD---LQMNWIDKRLS 306
++ L + Y++ S P + I VV + L A + + + +++ ++ W D +L
Sbjct: 15 LLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLR 74
Query: 307 WNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNGSVSWIKRLD 471
W+ ++ T + + SE +WRPD+VL N A GD+A+ +A + ++G V W
Sbjct: 75 WDPADYENVTSIRIPSELIWRPDIVLYNNAD---GDFAVTHLTKAHLFHDGRVQWTPPAI 131
Query: 472 ISTPISMQLDNWXNDMXTCTFXFGSRMHNSDXXDFV 579
+ S+ + + D CT FGS ++ D V
Sbjct: 132 YKSSCSIDVTFFPFDQQNCTMKFGSWTYDKAKIDLV 167
>U62433-1|AAB40111.1| 627|Homo sapiens nicotinic acetylcholine
receptor alpha4 subunit precursor protein.
Length = 627
Score = 53.2 bits (122), Expect = 1e-06
Identities = 40/156 (25%), Positives = 75/156 (48%), Gaps = 10/156 (6%)
Frame = +1
Query: 142 MIDSLLATYDRESPPDSKI--VVNLTLHLRHANIRESESTVRILAD---LQMNWIDKRLS 306
++ L + Y++ S P + I VV + L A + + + +++ ++ W D +L
Sbjct: 40 LLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLR 99
Query: 307 WNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNGSVSWIKRLD 471
W+ ++ T + + SE +WRPD+VL N A GD+A+ +A + ++G V W
Sbjct: 100 WDPADYENVTSIRIPSELIWRPDIVLYNNAD---GDFAVTHLTKAHLFHDGRVQWTPPAI 156
Query: 472 ISTPISMQLDNWXNDMXTCTFXFGSRMHNSDXXDFV 579
+ S+ + + D CT FGS ++ D V
Sbjct: 157 YKSSCSIDVTFFPFDQQNCTMKFGSWTYDKAKIDLV 192
>L35901-1|AAA64743.1| 627|Homo sapiens nicotinic acetylcholine
receptor alpha 4 subunit protein.
Length = 627
Score = 53.2 bits (122), Expect = 1e-06
Identities = 40/156 (25%), Positives = 75/156 (48%), Gaps = 10/156 (6%)
Frame = +1
Query: 142 MIDSLLATYDRESPPDSKI--VVNLTLHLRHANIRESESTVRILAD---LQMNWIDKRLS 306
++ L + Y++ S P + I VV + L A + + + +++ ++ W D +L
Sbjct: 40 LLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLR 99
Query: 307 WNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNGSVSWIKRLD 471
W+ ++ T + + SE +WRPD+VL N A GD+A+ +A + ++G V W
Sbjct: 100 WDPADYENVTSIRIPSELIWRPDIVLYNNAD---GDFAVTHLTKAHLFHDGRVQWTPPAI 156
Query: 472 ISTPISMQLDNWXNDMXTCTFXFGSRMHNSDXXDFV 579
+ S+ + + D CT FGS ++ D V
Sbjct: 157 YKSSCSIDVTFFPFDQQNCTMKFGSWTYDKAKIDLV 192
>DQ093071-1|AAY88737.1| 627|Homo sapiens cholinergic receptor,
nicotinic, alpha polypeptide 4 protein.
Length = 627
Score = 53.2 bits (122), Expect = 1e-06
Identities = 40/156 (25%), Positives = 75/156 (48%), Gaps = 10/156 (6%)
Frame = +1
Query: 142 MIDSLLATYDRESPPDSKI--VVNLTLHLRHANIRESESTVRILAD---LQMNWIDKRLS 306
++ L + Y++ S P + I VV + L A + + + +++ ++ W D +L
Sbjct: 40 LLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLR 99
Query: 307 WNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNGSVSWIKRLD 471
W+ ++ T + + SE +WRPD+VL N A GD+A+ +A + ++G V W
Sbjct: 100 WDPADYENVTSIRIPSELIWRPDIVLYNNAD---GDFAVTHLTKAHLFHDGRVQWTPPAI 156
Query: 472 ISTPISMQLDNWXNDMXTCTFXFGSRMHNSDXXDFV 579
+ S+ + + D CT FGS ++ D V
Sbjct: 157 YKSSCSIDVTFFPFDQQNCTMKFGSWTYDKAKIDLV 192
>BC096290-1|AAH96290.1| 627|Homo sapiens cholinergic receptor,
nicotinic, alpha 4 protein.
Length = 627
Score = 53.2 bits (122), Expect = 1e-06
Identities = 40/156 (25%), Positives = 75/156 (48%), Gaps = 10/156 (6%)
Frame = +1
Query: 142 MIDSLLATYDRESPPDSKI--VVNLTLHLRHANIRESESTVRILAD---LQMNWIDKRLS 306
++ L + Y++ S P + I VV + L A + + + +++ ++ W D +L
Sbjct: 40 LLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLR 99
Query: 307 WNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNGSVSWIKRLD 471
W+ ++ T + + SE +WRPD+VL N A GD+A+ +A + ++G V W
Sbjct: 100 WDPADYENVTSIRIPSELIWRPDIVLYNNAD---GDFAVTHLTKAHLFHDGRVQWTPPAI 156
Query: 472 ISTPISMQLDNWXNDMXTCTFXFGSRMHNSDXXDFV 579
+ S+ + + D CT FGS ++ D V
Sbjct: 157 YKSSCSIDVTFFPFDQQNCTMKFGSWTYDKAKIDLV 192
>X01715-1|CAA25861.1| 520|Homo sapiens acetylcholine receptor gamma
chain precursor protein.
Length = 520
Score = 52.4 bits (120), Expect = 2e-06
Identities = 40/152 (26%), Positives = 69/152 (45%), Gaps = 8/152 (5%)
Frame = +1
Query: 142 MIDSLLATYDRESPPDSKI--VVNLTLHLRHANI---RESESTVRILADLQMNWIDKRLS 306
++ L+ YD P + VVN++L L N+ E E + ++M W D RL
Sbjct: 32 LLADLMQNYDPNLRPAERDSDVVNVSLKLTLTNLISLNEREEALTTNVWIEMQWCDYRLR 91
Query: 307 WNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYAL--RARVSNNGSVSWIKRLDIS 477
W+ ++ G V S +WRPD+VL N + AL VS +G + W+
Sbjct: 92 WDPRDYEGLWVLRVPSTMVWRPDIVLEN-NVDGVFEVALYCNVLVSPDGCIYWLPPAIFR 150
Query: 478 TPISMQLDNWXNDMXTCTFXFGSRMHNSDXXD 573
+ S+ + + D C+ F S+ ++++ D
Sbjct: 151 SACSISVTYFPFDWQNCSLIFQSQTYSTNEID 182
>AC092165-3|AAY24103.1| 520|Homo sapiens unknown protein.
Length = 520
Score = 52.4 bits (120), Expect = 2e-06
Identities = 40/152 (26%), Positives = 69/152 (45%), Gaps = 8/152 (5%)
Frame = +1
Query: 142 MIDSLLATYDRESPPDSKI--VVNLTLHLRHANI---RESESTVRILADLQMNWIDKRLS 306
++ L+ YD P + VVN++L L N+ E E + ++M W D RL
Sbjct: 32 LLADLMQNYDPNLRPAERDSDVVNVSLKLTLTNLISLNEREEALTTNVWIEMQWCDYRLR 91
Query: 307 WNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYAL--RARVSNNGSVSWIKRLDIS 477
W+ ++ G V S +WRPD+VL N + AL VS +G + W+
Sbjct: 92 WDPRDYEGLWVLRVPSTMVWRPDIVLEN-NVDGVFEVALYCNVLVSPDGCIYWLPPAIFR 150
Query: 478 TPISMQLDNWXNDMXTCTFXFGSRMHNSDXXD 573
+ S+ + + D C+ F S+ ++++ D
Sbjct: 151 SACSISVTYFPFDWQNCSLIFQSQTYSTNEID 182
>BC113575-1|AAI13576.1| 479|Homo sapiens cholinergic receptor,
nicotinic, alpha 9 protein.
Length = 479
Score = 51.6 bits (118), Expect = 4e-06
Identities = 37/163 (22%), Positives = 72/163 (44%), Gaps = 7/163 (4%)
Frame = +1
Query: 106 AAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHANIRESESTVRILAD-- 273
AAE + + + L Y P D+ V+N+TL + + I++ + +IL
Sbjct: 22 AAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQITLSQIKDMDERNQILTAYL 81
Query: 274 -LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGD-YALRARVSNNG 444
++ W D L+W+ ++ G + + S+ +WRPD+VL N A + + + +G
Sbjct: 82 WIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKADDESSEPVNTNVVLRYDG 141
Query: 445 SVSWIKRLDISTPISMQLDNWXNDMXTCTFXFGSRMHNSDXXD 573
++W + + + + D C FGS +N + D
Sbjct: 142 LITWDAPAITKSSCVVDVTYFPFDNQQCNLTFGSWTYNGNQVD 184
>BC113549-1|AAI13550.1| 479|Homo sapiens cholinergic receptor,
nicotinic, alpha 9 protein.
Length = 479
Score = 51.6 bits (118), Expect = 4e-06
Identities = 37/163 (22%), Positives = 72/163 (44%), Gaps = 7/163 (4%)
Frame = +1
Query: 106 AAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHANIRESESTVRILAD-- 273
AAE + + + L Y P D+ V+N+TL + + I++ + +IL
Sbjct: 22 AAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQITLSQIKDMDERNQILTAYL 81
Query: 274 -LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGD-YALRARVSNNG 444
++ W D L+W+ ++ G + + S+ +WRPD+VL N A + + + +G
Sbjct: 82 WIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKADDESSEPVNTNVVLRYDG 141
Query: 445 SVSWIKRLDISTPISMQLDNWXNDMXTCTFXFGSRMHNSDXXD 573
++W + + + + D C FGS +N + D
Sbjct: 142 LITWDAPAITKSSCVVDVTYFPFDNQQCNLTFGSWTYNGNQVD 184
>AY123244-1|AAM74523.1| 479|Homo sapiens nicotinic acetylcholine
receptor subunit alpha 9 protein.
Length = 479
Score = 51.6 bits (118), Expect = 4e-06
Identities = 37/163 (22%), Positives = 72/163 (44%), Gaps = 7/163 (4%)
Frame = +1
Query: 106 AAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHANIRESESTVRILAD-- 273
AAE + + + L Y P D+ V+N+TL + + I++ + +IL
Sbjct: 22 AAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQITLSQIKDMDERNQILTAYL 81
Query: 274 -LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGD-YALRARVSNNG 444
++ W D L+W+ ++ G + + S+ +WRPD+VL N A + + + +G
Sbjct: 82 WIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKADDESSEPVNTNVVLRYDG 141
Query: 445 SVSWIKRLDISTPISMQLDNWXNDMXTCTFXFGSRMHNSDXXD 573
++W + + + + D C FGS +N + D
Sbjct: 142 LITWDAPAITKSSCVVDVTYFPFDNQQCNLTFGSWTYNGNQVD 184
>AJ243342-1|CAB65091.1| 479|Homo sapiens nicotinic acetylcholine
receptor alpha 9 subunit protein.
Length = 479
Score = 51.6 bits (118), Expect = 4e-06
Identities = 37/163 (22%), Positives = 72/163 (44%), Gaps = 7/163 (4%)
Frame = +1
Query: 106 AAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHANIRESESTVRILAD-- 273
AAE + + + L Y P D+ V+N+TL + + I++ + +IL
Sbjct: 22 AAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQITLSQIKDMDERNQILTAYL 81
Query: 274 -LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGD-YALRARVSNNG 444
++ W D L+W+ ++ G + + S+ +WRPD+VL N A + + + +G
Sbjct: 82 WIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKADDESSEPVNTNVVLRYDG 141
Query: 445 SVSWIKRLDISTPISMQLDNWXNDMXTCTFXFGSRMHNSDXXD 573
++W + + + + D C FGS +N + D
Sbjct: 142 LITWDAPAITKSSCVVDVTYFPFDNQQCNLTFGSWTYNGNQVD 184
>AF227732-1|AAF61920.1| 470|Homo sapiens nicotinic acetylcholine
receptor alpha 9 subunit protein.
Length = 470
Score = 51.6 bits (118), Expect = 4e-06
Identities = 37/163 (22%), Positives = 72/163 (44%), Gaps = 7/163 (4%)
Frame = +1
Query: 106 AAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHANIRESESTVRILAD-- 273
AAE + + + L Y P D+ V+N+TL + + I++ + +IL
Sbjct: 16 AAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQITLSQIKDMDERNQILTAYL 75
Query: 274 -LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGD-YALRARVSNNG 444
++ W D L+W+ ++ G + + S+ +WRPD+VL N A + + + +G
Sbjct: 76 WIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKADDESSEPVNTNVVLRYDG 135
Query: 445 SVSWIKRLDISTPISMQLDNWXNDMXTCTFXFGSRMHNSDXXD 573
++W + + + + D C FGS +N + D
Sbjct: 136 LITWDAPAITKSSCVVDVTYFPFDNQQCNLTFGSWTYNGNQVD 178
>AC118275-1|AAY40986.1| 479|Homo sapiens unknown protein.
Length = 479
Score = 51.6 bits (118), Expect = 4e-06
Identities = 37/163 (22%), Positives = 72/163 (44%), Gaps = 7/163 (4%)
Frame = +1
Query: 106 AAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHANIRESESTVRILAD-- 273
AAE + + + L Y P D+ V+N+TL + + I++ + +IL
Sbjct: 22 AAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQITLSQIKDMDERNQILTAYL 81
Query: 274 -LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGD-YALRARVSNNG 444
++ W D L+W+ ++ G + + S+ +WRPD+VL N A + + + +G
Sbjct: 82 WIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKADDESSEPVNTNVVLRYDG 141
Query: 445 SVSWIKRLDISTPISMQLDNWXNDMXTCTFXFGSRMHNSDXXD 573
++W + + + + D C FGS +N + D
Sbjct: 142 LITWDAPAITKSSCVVDVTYFPFDNQQCNLTFGSWTYNGNQVD 184
>Y08415-1|CAA69692.1| 502|Homo sapiens nicotinic acetylcholine
receptor beta2 subunit precursor protein.
Length = 502
Score = 50.4 bits (115), Expect = 8e-06
Identities = 37/150 (24%), Positives = 63/150 (42%), Gaps = 6/150 (4%)
Frame = +1
Query: 196 IVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 369
+ V L + L ++ E E + L W D RL+W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 370 DVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWXNDMXTCTFXFGS 546
DVVL N A + A VS +GS+ W+ + +++ ++ D CT F S
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRS 175
Query: 547 RMHNSDXXDFVIDXXIYXM---FXSXAWDV 627
++ D V+ + + S WD+
Sbjct: 176 WTYDRTEIDLVLKSEVASLDDFTPSGEWDI 205
>X53179-1|CAA37320.1| 502|Homo sapiens precursor peptide (AA -25 to
477) protein.
Length = 502
Score = 50.4 bits (115), Expect = 8e-06
Identities = 37/150 (24%), Positives = 63/150 (42%), Gaps = 6/150 (4%)
Frame = +1
Query: 196 IVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 369
+ V L + L ++ E E + L W D RL+W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 370 DVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWXNDMXTCTFXFGS 546
DVVL N A + A VS +GS+ W+ + +++ ++ D CT F S
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRS 175
Query: 547 RMHNSDXXDFVIDXXIYXM---FXSXAWDV 627
++ D V+ + + S WD+
Sbjct: 176 WTYDRTEIDLVLKSEVASLDDFTPSGEWDI 205
>U62437-1|AAB40115.1| 502|Homo sapiens nicotinic acetylcholine
receptor beta2 subunit precursor protein.
Length = 502
Score = 50.4 bits (115), Expect = 8e-06
Identities = 37/150 (24%), Positives = 63/150 (42%), Gaps = 6/150 (4%)
Frame = +1
Query: 196 IVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 369
+ V L + L ++ E E + L W D RL+W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 370 DVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWXNDMXTCTFXFGS 546
DVVL N A + A VS +GS+ W+ + +++ ++ D CT F S
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRS 175
Query: 547 RMHNSDXXDFVIDXXIYXM---FXSXAWDV 627
++ D V+ + + S WD+
Sbjct: 176 WTYDRTEIDLVLKSEVASLDDFTPSGEWDI 205
>BC075041-1|AAH75041.1| 502|Homo sapiens cholinergic receptor,
nicotinic, beta 2 (neuronal) protein.
Length = 502
Score = 50.4 bits (115), Expect = 8e-06
Identities = 37/150 (24%), Positives = 63/150 (42%), Gaps = 6/150 (4%)
Frame = +1
Query: 196 IVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 369
+ V L + L ++ E E + L W D RL+W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 370 DVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWXNDMXTCTFXFGS 546
DVVL N A + A VS +GS+ W+ + +++ ++ D CT F S
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRS 175
Query: 547 RMHNSDXXDFVIDXXIYXM---FXSXAWDV 627
++ D V+ + + S WD+
Sbjct: 176 WTYDRTEIDLVLKSEVASLDDFTPSGEWDI 205
>BC075040-1|AAH75040.1| 502|Homo sapiens cholinergic receptor,
nicotinic, beta 2 (neuronal) protein.
Length = 502
Score = 50.4 bits (115), Expect = 8e-06
Identities = 37/150 (24%), Positives = 63/150 (42%), Gaps = 6/150 (4%)
Frame = +1
Query: 196 IVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 369
+ V L + L ++ E E + L W D RL+W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 370 DVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWXNDMXTCTFXFGS 546
DVVL N A + A VS +GS+ W+ + +++ ++ D CT F S
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRS 175
Query: 547 RMHNSDXXDFVIDXXIYXM---FXSXAWDV 627
++ D V+ + + S WD+
Sbjct: 176 WTYDRTEIDLVLKSEVASLDDFTPSGEWDI 205
>AL592078-3|CAI16184.1| 502|Homo sapiens cholinergic receptor,
nicotinic, beta 2 (neuronal) protein.
Length = 502
Score = 50.4 bits (115), Expect = 8e-06
Identities = 37/150 (24%), Positives = 63/150 (42%), Gaps = 6/150 (4%)
Frame = +1
Query: 196 IVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 369
+ V L + L ++ E E + L W D RL+W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 370 DVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWXNDMXTCTFXFGS 546
DVVL N A + A VS +GS+ W+ + +++ ++ D CT F S
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRS 175
Query: 547 RMHNSDXXDFVIDXXIYXM---FXSXAWDV 627
++ D V+ + + S WD+
Sbjct: 176 WTYDRTEIDLVLKSEVASLDDFTPSGEWDI 205
>AJ295237-1|CAC16144.1| 450|Homo sapiens neuronal nicotinic
acetylcholine receptor subunit4 protein.
Length = 450
Score = 50.4 bits (115), Expect = 8e-06
Identities = 43/165 (26%), Positives = 69/165 (41%), Gaps = 10/165 (6%)
Frame = +1
Query: 109 AEC---ENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHANIRESESTVRILAD 273
AEC E +L L D L A Y P D+ +N+TL + + I + + ++L
Sbjct: 20 AECLGAEGRLALKLFRD-LFANYTSALRPVADTDQTLNVTLEVTLSQIIDMDERNQVLTL 78
Query: 274 ---LQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSN 438
++ W D L W+ +G + S +WRPD+VL N A A G + + +
Sbjct: 79 YLWIRQEWTDAYLRWDPNAYGGLDAIRIPSSLVWRPDIVLYNKADAQPPGSASTNVVLRH 138
Query: 439 NGSVSWIKRLDISTPISMQLDNWXNDMXTCTFXFGSRMHNSDXXD 573
+G+V W + + + + D C FGS H D
Sbjct: 139 DGAVRWDAPAITRSSCRVDVAAFPFDAQHCGLTFGSWTHGGHQLD 183
>AJ278118-1|CAC20435.1| 450|Homo sapiens neuronal nicotinic
acetylcholine alpha10 subunit protein.
Length = 450
Score = 50.4 bits (115), Expect = 8e-06
Identities = 43/165 (26%), Positives = 69/165 (41%), Gaps = 10/165 (6%)
Frame = +1
Query: 109 AEC---ENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHANIRESESTVRILAD 273
AEC E +L L D L A Y P D+ +N+TL + + I + + ++L
Sbjct: 20 AECLGAEGRLALKLFRD-LFANYTSALRPVADTDQTLNVTLEVTLSQIIDMDERNQVLTL 78
Query: 274 ---LQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSN 438
++ W D L W+ +G + S +WRPD+VL N A A G + + +
Sbjct: 79 YLWIRQEWTDAYLRWDPNAYGGLDAIRIPSSLVWRPDIVLYNKADAQPPGSASTNVVLRH 138
Query: 439 NGSVSWIKRLDISTPISMQLDNWXNDMXTCTFXFGSRMHNSDXXD 573
+G+V W + + + + D C FGS H D
Sbjct: 139 DGAVRWDAPAITRSSCRVDVAAFPFDAQHCGLTFGSWTHGGHQLD 183
>AJ001935-1|CAA05108.1| 504|Homo sapiens CHRNB2 protein.
Length = 504
Score = 50.4 bits (115), Expect = 8e-06
Identities = 37/150 (24%), Positives = 63/150 (42%), Gaps = 6/150 (4%)
Frame = +1
Query: 196 IVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 369
+ V L + L ++ E E + L W D RL+W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 370 DVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWXNDMXTCTFXFGS 546
DVVL N A + A VS +GS+ W+ + +++ ++ D CT F S
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRS 175
Query: 547 RMHNSDXXDFVIDXXIYXM---FXSXAWDV 627
++ D V+ + + S WD+
Sbjct: 176 WTYDRTEIDLVLKSEVASLDDFTPSGEWDI 205
>AF327367-1|AAK14333.1| 450|Homo sapiens nicotinic acetylcholine
receptor subunit alpha 10 protein.
Length = 450
Score = 50.4 bits (115), Expect = 8e-06
Identities = 43/165 (26%), Positives = 69/165 (41%), Gaps = 10/165 (6%)
Frame = +1
Query: 109 AEC---ENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHANIRESESTVRILAD 273
AEC E +L L D L A Y P D+ +N+TL + + I + + ++L
Sbjct: 20 AECLGAEGRLALKLFRD-LFANYTSALRPVADTDQTLNVTLEVTLSQIIDMDERNQVLTL 78
Query: 274 ---LQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSN 438
++ W D L W+ +G + S +WRPD+VL N A A G + + +
Sbjct: 79 YLWIRQEWTDAYLRWDPNAYGGLDAIRIPSSLVWRPDIVLYNKADAQPPGSASTNVVLRH 138
Query: 439 NGSVSWIKRLDISTPISMQLDNWXNDMXTCTFXFGSRMHNSDXXD 573
+G+V W + + + + D C FGS H D
Sbjct: 139 DGAVRWDAPAITRSSCRVDVAAFPFDAQHCGLTFGSWTHGGHQLD 183
>AF199235-1|AAG00795.2| 450|Homo sapiens nicotinic acetylcholine
receptor subunit alpha 10 protein.
Length = 450
Score = 50.4 bits (115), Expect = 8e-06
Identities = 43/165 (26%), Positives = 69/165 (41%), Gaps = 10/165 (6%)
Frame = +1
Query: 109 AEC---ENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHANIRESESTVRILAD 273
AEC E +L L D L A Y P D+ +N+TL + + I + + ++L
Sbjct: 20 AECLGAEGRLALKLFRD-LFANYTSALRPVADTDQTLNVTLEVTLSQIIDMDERNQVLTL 78
Query: 274 ---LQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSN 438
++ W D L W+ +G + S +WRPD+VL N A A G + + +
Sbjct: 79 YLWIRQEWTDAYLRWDPNAYGGLDAIRIPSSLVWRPDIVLYNKADAQPPGSASTNVVLRH 138
Query: 439 NGSVSWIKRLDISTPISMQLDNWXNDMXTCTFXFGSRMHNSDXXD 573
+G+V W + + + + D C FGS H D
Sbjct: 139 DGAVRWDAPAITRSSCRVDVAAFPFDAQHCGLTFGSWTHGGHQLD 183
>AF077186-1|AAD45422.1| 502|Homo sapiens neuronal nicotinic
acetylcholine receptor beta 2 protein.
Length = 502
Score = 50.4 bits (115), Expect = 8e-06
Identities = 37/150 (24%), Positives = 63/150 (42%), Gaps = 6/150 (4%)
Frame = +1
Query: 196 IVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 369
+ V L + L ++ E E + L W D RL+W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 370 DVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWXNDMXTCTFXFGS 546
DVVL N A + A VS +GS+ W+ + +++ ++ D CT F S
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRS 175
Query: 547 RMHNSDXXDFVIDXXIYXM---FXSXAWDV 627
++ D V+ + + S WD+
Sbjct: 176 WTYDRTEIDLVLKSEVASLDDFTPSGEWDI 205
>Y00762-1|CAA68731.1| 457|Homo sapiens protein ( Human mRNA for
muscle acetylcholine receptor alpha-subunit. ).
Length = 457
Score = 49.6 bits (113), Expect = 1e-05
Identities = 31/123 (25%), Positives = 58/123 (47%), Gaps = 5/123 (4%)
Frame = +1
Query: 193 KIVVNLTLHLRHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRP 369
++ V L L ++ N+ E V L+ W+D L WN ++G + + SE++WRP
Sbjct: 50 EVTVGLQL-IQLINVDEVNQIVTTNVRLKQQWVDYNLKWNPDDYGGVKKIHIPSEKIWRP 108
Query: 370 DVVLLNAAATTAGDYAL----RARVSNNGSVSWIKRLDISTPISMQLDNWXNDMXTCTFX 537
D+VL N A GD+A+ + + G ++W + + + ++ D C+
Sbjct: 109 DLVLYNNA---DGDFAIVKFTKVLLQYTGHITWTPPAIFKSYCEIIVTHFPFDEQNCSMK 165
Query: 538 FGS 546
G+
Sbjct: 166 LGT 168
>X02502-1|CAA26344.1| 457|Homo sapiens acetylcholine receptor
protein.
Length = 457
Score = 49.6 bits (113), Expect = 1e-05
Identities = 31/123 (25%), Positives = 58/123 (47%), Gaps = 5/123 (4%)
Frame = +1
Query: 193 KIVVNLTLHLRHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRP 369
++ V L L ++ N+ E V L+ W+D L WN ++G + + SE++WRP
Sbjct: 50 EVTVGLQL-IQLINVDEVNQIVTTNVRLKQQWVDYNLKWNPDDYGGVKKIHIPSEKIWRP 108
Query: 370 DVVLLNAAATTAGDYAL----RARVSNNGSVSWIKRLDISTPISMQLDNWXNDMXTCTFX 537
D+VL N A GD+A+ + + G ++W + + + ++ D C+
Sbjct: 109 DLVLYNNA---DGDFAIVKFTKVLLQYTGHITWTPPAIFKSYCEIIVTHFPFDEQNCSMK 165
Query: 538 FGS 546
G+
Sbjct: 166 LGT 168
>S77094-1|AAD14247.1| 457|Homo sapiens nicotinic acetylcholine
receptor alpha subunit|AChR protein.
Length = 457
Score = 49.6 bits (113), Expect = 1e-05
Identities = 31/123 (25%), Positives = 58/123 (47%), Gaps = 5/123 (4%)
Frame = +1
Query: 193 KIVVNLTLHLRHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRP 369
++ V L L ++ N+ E V L+ W+D L WN ++G + + SE++WRP
Sbjct: 50 EVTVGLQL-IQLINVDEVNQIVTTNVRLKQQWVDYNLKWNPDDYGGVKKIHIPSEKIWRP 108
Query: 370 DVVLLNAAATTAGDYAL----RARVSNNGSVSWIKRLDISTPISMQLDNWXNDMXTCTFX 537
D+VL N A GD+A+ + + G ++W + + + ++ D C+
Sbjct: 109 DLVLYNNA---DGDFAIVKFTKVLLQYTGHITWTPPAIFKSYCEIIVTHFPFDEQNCSMK 165
Query: 538 FGS 546
G+
Sbjct: 166 LGT 168
>BC111802-1|AAI11803.1| 465|Homo sapiens CHRNG protein protein.
Length = 465
Score = 49.6 bits (113), Expect = 1e-05
Identities = 33/113 (29%), Positives = 54/113 (47%), Gaps = 7/113 (6%)
Frame = +1
Query: 142 MIDSLLATYDRESPPDSKI--VVNLTLHLRHANI---RESESTVRILADLQMNWIDKRLS 306
++ L+ YD P + VVN++L L N+ E E + ++M W D RL
Sbjct: 29 LLADLMQNYDPNLRPAERDSDVVNVSLKLTLTNLISLNEREEALTTNVWIEMQWCDYRLR 88
Query: 307 WNAGEW-GCSTWLVSSERLWRPDVVLLNAAAT-TAGDYALRARVSNNGSVSWI 459
W+ ++ G V S +WRPD+VL N + T + + L+ + S+ WI
Sbjct: 89 WDPRDYEGLWVLRVPSTMVWRPDIVLENKSQTYSTNEIDLQLSQEDGQSIEWI 141
>BC006314-1|AAH06314.1| 269|Homo sapiens CHRNA1 protein protein.
Length = 269
Score = 49.6 bits (113), Expect = 1e-05
Identities = 31/123 (25%), Positives = 58/123 (47%), Gaps = 5/123 (4%)
Frame = +1
Query: 193 KIVVNLTLHLRHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRP 369
++ V L L ++ N+ E V L+ W+D L WN ++G + + SE++WRP
Sbjct: 50 EVTVGLQL-IQLINVDEVNQIVTTNVRLKQQWVDYNLKWNPDDYGGVKKIHIPSEKIWRP 108
Query: 370 DVVLLNAAATTAGDYAL----RARVSNNGSVSWIKRLDISTPISMQLDNWXNDMXTCTFX 537
D+VL N A GD+A+ + + G ++W + + + ++ D C+
Sbjct: 109 DLVLYNNA---DGDFAIVKFTKVLLQYTGHITWTPPAIFKSYCEIIVTHFPFDEQNCSMK 165
Query: 538 FGS 546
G+
Sbjct: 166 LGT 168
>AC018890-1|AAY14687.1| 457|Homo sapiens unknown protein.
Length = 457
Score = 49.6 bits (113), Expect = 1e-05
Identities = 31/123 (25%), Positives = 58/123 (47%), Gaps = 5/123 (4%)
Frame = +1
Query: 193 KIVVNLTLHLRHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRP 369
++ V L L ++ N+ E V L+ W+D L WN ++G + + SE++WRP
Sbjct: 50 EVTVGLQL-IQLINVDEVNQIVTTNVRLKQQWVDYNLKWNPDDYGGVKKIHIPSEKIWRP 108
Query: 370 DVVLLNAAATTAGDYAL----RARVSNNGSVSWIKRLDISTPISMQLDNWXNDMXTCTFX 537
D+VL N A GD+A+ + + G ++W + + + ++ D C+
Sbjct: 109 DLVLYNNA---DGDFAIVKFTKVLLQYTGHITWTPPAIFKSYCEIIVTHFPFDEQNCSMK 165
Query: 538 FGS 546
G+
Sbjct: 166 LGT 168
>DQ644022-1|ABG35128.1| 456|Homo sapiens 5-HT3 receptor subunit E
splice variant HTR3Ea protein.
Length = 456
Score = 48.8 bits (111), Expect = 3e-05
Identities = 25/98 (25%), Positives = 47/98 (47%), Gaps = 1/98 (1%)
Frame = +1
Query: 274 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 450
L+M W + +SWN E G + ++++ LW PD+ ++ L A VSN G +
Sbjct: 91 LEMVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEGRI 150
Query: 451 SWIKRLDISTPISMQLDNWXNDMXTCTFXFGSRMHNSD 564
+ K + + + ++ + + D CT F S ++ D
Sbjct: 151 RYKKPMKVDSICNLDIFYFPFDQQNCTLTFSSFLYTVD 188
>BC101185-1|AAI01186.1| 374|Homo sapiens HTR3E protein protein.
Length = 374
Score = 48.8 bits (111), Expect = 3e-05
Identities = 25/98 (25%), Positives = 47/98 (47%), Gaps = 1/98 (1%)
Frame = +1
Query: 274 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 450
L+M W + +SWN E G + ++++ LW PD+ ++ L A VSN G +
Sbjct: 20 LEMVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEGRI 79
Query: 451 SWIKRLDISTPISMQLDNWXNDMXTCTFXFGSRMHNSD 564
+ K + + + ++ + + D CT F S ++ D
Sbjct: 80 RYKKPMKVDSICNLDIFYFPFDQQNCTLTFSSFLYTVD 117
>BC101183-1|AAI01184.1| 471|Homo sapiens 5-hydroxytryptamine
(serotonin) receptor 3, family member E protein.
Length = 471
Score = 48.8 bits (111), Expect = 3e-05
Identities = 25/98 (25%), Positives = 47/98 (47%), Gaps = 1/98 (1%)
Frame = +1
Query: 274 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 450
L+M W + +SWN E G + ++++ LW PD+ ++ L A VSN G +
Sbjct: 106 LEMVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEGRI 165
Query: 451 SWIKRLDISTPISMQLDNWXNDMXTCTFXFGSRMHNSD 564
+ K + + + ++ + + D CT F S ++ D
Sbjct: 166 RYKKPMKVDSICNLDIFYFPFDQQNCTLTFSSFLYTVD 203
>BC101182-1|AAI01183.1| 471|Homo sapiens 5-hydroxytryptamine
(serotonin) receptor 3, family member E protein.
Length = 471
Score = 48.8 bits (111), Expect = 3e-05
Identities = 25/98 (25%), Positives = 47/98 (47%), Gaps = 1/98 (1%)
Frame = +1
Query: 274 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 450
L+M W + +SWN E G + ++++ LW PD+ ++ L A VSN G +
Sbjct: 106 LEMVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEGRI 165
Query: 451 SWIKRLDISTPISMQLDNWXNDMXTCTFXFGSRMHNSD 564
+ K + + + ++ + + D CT F S ++ D
Sbjct: 166 RYKKPMKVDSICNLDIFYFPFDQQNCTLTFSSFLYTVD 203
>AY159813-1|AAO38167.2| 471|Homo sapiens 5-hydroxytryptamine
serotonin receptor 3E protein.
Length = 471
Score = 48.8 bits (111), Expect = 3e-05
Identities = 25/98 (25%), Positives = 47/98 (47%), Gaps = 1/98 (1%)
Frame = +1
Query: 274 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 450
L+M W + +SWN E G + ++++ LW PD+ ++ L A VSN G +
Sbjct: 106 LEMVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEGRI 165
Query: 451 SWIKRLDISTPISMQLDNWXNDMXTCTFXFGSRMHNSD 564
+ K + + + ++ + + D CT F S ++ D
Sbjct: 166 RYKKPMKVDSICNLDIFYFPFDQQNCTLTFSSFLYTVD 203
>S77554-1|AAB33983.1| 474|Homo sapiens GABAA receptor beta 2
subunit protein.
Length = 474
Score = 48.4 bits (110), Expect = 3e-05
Identities = 41/182 (22%), Positives = 75/182 (41%), Gaps = 10/182 (5%)
Frame = +1
Query: 61 YYSXYRFSSLDAIASAAECENATSLSLM---IDSLLATYDRESPPD---SKIVVNLTLHL 222
Y+ + F + A A + +++SL+ +D LL YD PD + V + + +
Sbjct: 9 YFGIWSFPLIIAAVCAQSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDI 68
Query: 223 RHAN-IRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAAT 399
+ + E + Q W DKRLS+N + +++LW PD LN +
Sbjct: 69 ASIDMVSEVNMDYTLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLNDKKS 128
Query: 400 TAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWXNDMXTCTFXFGSRMHNSDXX 570
++ R+ +G+V + R+ + M L + D CT S + +D
Sbjct: 129 FVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDI 188
Query: 571 DF 576
+F
Sbjct: 189 EF 190
>S77553-1|AAB33982.1| 512|Homo sapiens GABAA receptor beta 2
subunit protein.
Length = 512
Score = 48.4 bits (110), Expect = 3e-05
Identities = 41/182 (22%), Positives = 75/182 (41%), Gaps = 10/182 (5%)
Frame = +1
Query: 61 YYSXYRFSSLDAIASAAECENATSLSLM---IDSLLATYDRESPPD---SKIVVNLTLHL 222
Y+ + F + A A + +++SL+ +D LL YD PD + V + + +
Sbjct: 9 YFGIWSFPLIIAAVCAQSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDI 68
Query: 223 RHAN-IRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAAT 399
+ + E + Q W DKRLS+N + +++LW PD LN +
Sbjct: 69 ASIDMVSEVNMDYTLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLNDKKS 128
Query: 400 TAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWXNDMXTCTFXFGSRMHNSDXX 570
++ R+ +G+V + R+ + M L + D CT S + +D
Sbjct: 129 FVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDI 188
Query: 571 DF 576
+F
Sbjct: 189 EF 190
>S67368-1|AAB29370.1| 474|Homo sapiens gamma-aminobutyric acid A
receptor beta 2 subunit protein.
Length = 474
Score = 48.4 bits (110), Expect = 3e-05
Identities = 41/182 (22%), Positives = 75/182 (41%), Gaps = 10/182 (5%)
Frame = +1
Query: 61 YYSXYRFSSLDAIASAAECENATSLSLM---IDSLLATYDRESPPD---SKIVVNLTLHL 222
Y+ + F + A A + +++SL+ +D LL YD PD + V + + +
Sbjct: 9 YFGIWSFPLIIAAVCAQSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDI 68
Query: 223 RHAN-IRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAAT 399
+ + E + Q W DKRLS+N + +++LW PD LN +
Sbjct: 69 ASIDMVSEVNMDYTLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLNDKKS 128
Query: 400 TAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWXNDMXTCTFXFGSRMHNSDXX 570
++ R+ +G+V + R+ + M L + D CT S + +D
Sbjct: 129 FVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDI 188
Query: 571 DF 576
+F
Sbjct: 189 EF 190
>BC105639-1|AAI05640.1| 474|Homo sapiens GABRB2 protein protein.
Length = 474
Score = 48.4 bits (110), Expect = 3e-05
Identities = 41/182 (22%), Positives = 75/182 (41%), Gaps = 10/182 (5%)
Frame = +1
Query: 61 YYSXYRFSSLDAIASAAECENATSLSLM---IDSLLATYDRESPPD---SKIVVNLTLHL 222
Y+ + F + A A + +++SL+ +D LL YD PD + V + + +
Sbjct: 9 YFGIWSFPLIIAAVCAQSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDI 68
Query: 223 RHAN-IRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAAT 399
+ + E + Q W DKRLS+N + +++LW PD LN +
Sbjct: 69 ASIDMVSEVNMDYTLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLNDKKS 128
Query: 400 TAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWXNDMXTCTFXFGSRMHNSDXX 570
++ R+ +G+V + R+ + M L + D CT S + +D
Sbjct: 129 FVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDI 188
Query: 571 DF 576
+F
Sbjct: 189 EF 190
>BC099719-1|AAH99719.1| 474|Homo sapiens GABRB2 protein protein.
Length = 474
Score = 48.4 bits (110), Expect = 3e-05
Identities = 41/182 (22%), Positives = 75/182 (41%), Gaps = 10/182 (5%)
Frame = +1
Query: 61 YYSXYRFSSLDAIASAAECENATSLSLM---IDSLLATYDRESPPD---SKIVVNLTLHL 222
Y+ + F + A A + +++SL+ +D LL YD PD + V + + +
Sbjct: 9 YFGIWSFPLIIAAVCAQSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDI 68
Query: 223 RHAN-IRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAAT 399
+ + E + Q W DKRLS+N + +++LW PD LN +
Sbjct: 69 ASIDMVSEVNMDYTLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLNDKKS 128
Query: 400 TAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWXNDMXTCTFXFGSRMHNSDXX 570
++ R+ +G+V + R+ + M L + D CT S + +D
Sbjct: 129 FVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDI 188
Query: 571 DF 576
+F
Sbjct: 189 EF 190
>BC099705-1|AAH99705.1| 474|Homo sapiens GABRB2 protein protein.
Length = 474
Score = 48.4 bits (110), Expect = 3e-05
Identities = 41/182 (22%), Positives = 75/182 (41%), Gaps = 10/182 (5%)
Frame = +1
Query: 61 YYSXYRFSSLDAIASAAECENATSLSLM---IDSLLATYDRESPPD---SKIVVNLTLHL 222
Y+ + F + A A + +++SL+ +D LL YD PD + V + + +
Sbjct: 9 YFGIWSFPLIIAAVCAQSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDI 68
Query: 223 RHAN-IRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAAT 399
+ + E + Q W DKRLS+N + +++LW PD LN +
Sbjct: 69 ASIDMVSEVNMDYTLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLNDKKS 128
Query: 400 TAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWXNDMXTCTFXFGSRMHNSDXX 570
++ R+ +G+V + R+ + M L + D CT S + +D
Sbjct: 129 FVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDI 188
Query: 571 DF 576
+F
Sbjct: 189 EF 190
>BC131799-1|AAI31800.1| 447|Homo sapiens 5-hydroxytryptamine
(serotonin) receptor 3, family member C protein.
Length = 447
Score = 47.6 bits (108), Expect = 6e-05
Identities = 24/109 (22%), Positives = 52/109 (47%), Gaps = 1/109 (0%)
Frame = +1
Query: 274 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 450
+ + W + ++WN E G + V +E LW PD+ ++ + L A +S+ G +
Sbjct: 91 MDLVWDNPFINWNPKECVGINKLTVLAENLWLPDIFIVESMDVDQTPSGLTAYISSEGRI 150
Query: 451 SWIKRLDISTPISMQLDNWXNDMXTCTFXFGSRMHNSDXXDFVIDXXIY 597
+ K + +++ ++ + + D CTF F S ++ D +D ++
Sbjct: 151 KYDKPMRVTSICNLDIFYFPFDQQNCTFTFSSFLYTVDSMLLGMDKEVW 199
>AF459285-1|AAL66182.1| 447|Homo sapiens 5-hydroxytryptamine
receptor 3 subunit C protein.
Length = 447
Score = 47.2 bits (107), Expect = 8e-05
Identities = 24/109 (22%), Positives = 51/109 (46%), Gaps = 1/109 (0%)
Frame = +1
Query: 274 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 450
+ + W + ++WN E G + V +E LW PD+ ++ + L A +S+ G +
Sbjct: 91 MDLVWDNPFINWNPKECVGINKLTVLAENLWLPDIFIVESMDVDQTPSGLTAYISSEGRI 150
Query: 451 SWIKRLDISTPISMQLDNWXNDMXTCTFXFGSRMHNSDXXDFVIDXXIY 597
+ K + +++ + + + D CTF F S ++ D +D ++
Sbjct: 151 KYDKPMRVTSICKLDIFYFPFDQQNCTFTFSSFLYTVDSMLLGMDKEVW 199
>BC110597-1|AAI10598.1| 411|Homo sapiens ligand-gated ion channel,
zinc activated 1 protein.
Length = 411
Score = 46.8 bits (106), Expect = 1e-04
Identities = 25/89 (28%), Positives = 41/89 (46%)
Frame = +1
Query: 274 LQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVS 453
L+++W+D RL+WN + E LW P + +L A D + +ARV +G V
Sbjct: 86 LRLSWLDTRLAWNTSAHPRHAITLPWESLWTPRLTILEALWVDWRDQSPQARVDQDGHVK 145
Query: 454 WIKRLDISTPISMQLDNWXNDMXTCTFXF 540
L T + +L ++ D C+ F
Sbjct: 146 LNLALTTETNCNFELLHFPRDHSNCSLSF 174
>BC096083-1|AAH96083.1| 198|Homo sapiens CHRNB4 protein protein.
Length = 198
Score = 46.8 bits (106), Expect = 1e-04
Identities = 31/117 (26%), Positives = 55/117 (47%), Gaps = 8/117 (6%)
Frame = +1
Query: 88 LDAIASAAECENATSLSLMIDSLL--ATYDRESPP--DSKIVVNLTLHLRHA---NIRES 246
L A+ C A + ++D LL Y+ P S ++++ L L A ++ E
Sbjct: 12 LVALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNER 71
Query: 247 ESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDY 414
E + L+ W D RL+WN+ + G + + ++R+W PD+VL N + T +
Sbjct: 72 EQIMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNKSLRTGSTW 128
>BC096081-1|AAH96081.1| 198|Homo sapiens CHRNB4 protein protein.
Length = 198
Score = 46.8 bits (106), Expect = 1e-04
Identities = 31/117 (26%), Positives = 55/117 (47%), Gaps = 8/117 (6%)
Frame = +1
Query: 88 LDAIASAAECENATSLSLMIDSLL--ATYDRESPP--DSKIVVNLTLHLRHA---NIRES 246
L A+ C A + ++D LL Y+ P S ++++ L L A ++ E
Sbjct: 12 LVALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNER 71
Query: 247 ESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDY 414
E + L+ W D RL+WN+ + G + + ++R+W PD+VL N + T +
Sbjct: 72 EQIMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNKSLRTGSTW 128
>AY349353-1|AAQ93477.1| 456|Homo sapiens 5-HT3c1 serotonin
receptor-like protein protein.
Length = 456
Score = 46.8 bits (106), Expect = 1e-04
Identities = 25/100 (25%), Positives = 47/100 (47%), Gaps = 1/100 (1%)
Frame = +1
Query: 268 ADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNG 444
A L + W + +SWN E G + ++++ LW PD+ ++ L A VSN G
Sbjct: 89 AILDVVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEG 148
Query: 445 SVSWIKRLDISTPISMQLDNWXNDMXTCTFXFGSRMHNSD 564
+ + K + + + ++ + + D CT F S ++ D
Sbjct: 149 RIRYKKPMKVDSICNLDIFYFPFDQQNCTLTFSSFLYTVD 188
>AY349352-1|AAQ93476.1| 441|Homo sapiens 5-HT3c1 serotonin
receptor-like protein protein.
Length = 441
Score = 46.8 bits (106), Expect = 1e-04
Identities = 25/100 (25%), Positives = 47/100 (47%), Gaps = 1/100 (1%)
Frame = +1
Query: 268 ADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNG 444
A L + W + +SWN E G + ++++ LW PD+ ++ L A VSN G
Sbjct: 74 AILDVVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEG 133
Query: 445 SVSWIKRLDISTPISMQLDNWXNDMXTCTFXFGSRMHNSD 564
+ + K + + + ++ + + D CT F S ++ D
Sbjct: 134 RIRYKKPMKVDSICNLDIFYFPFDQQNCTLTFSSFLYTVD 173
>AK122638-1|BAC85499.1| 266|Homo sapiens yte protein of 76kDa)
(LCP2). protein.
Length = 266
Score = 46.8 bits (106), Expect = 1e-04
Identities = 25/89 (28%), Positives = 41/89 (46%)
Frame = +1
Query: 274 LQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVS 453
L+++W+D RL+WN + E LW P + +L A D + +ARV +G V
Sbjct: 87 LRLSWLDTRLAWNTSAHPRHAITLPWESLWTPRLTILEALWVDWRDQSPQARVDQDGHVK 146
Query: 454 WIKRLDISTPISMQLDNWXNDMXTCTFXF 540
L T + +L ++ D C+ F
Sbjct: 147 LNLALTTETNCNFELLHFPRDHSNCSLSF 175
>AF512521-1|AAO20969.1| 411|Homo sapiens ligand-gated ion channel
subunit protein.
Length = 411
Score = 46.8 bits (106), Expect = 1e-04
Identities = 25/89 (28%), Positives = 41/89 (46%)
Frame = +1
Query: 274 LQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVS 453
L+++W+D RL+WN + E LW P + +L A D + +ARV +G V
Sbjct: 86 LRLSWLDTRLAWNTSAHPRHAITLPWESLWTPRLTILEALWVDWRDQSPQARVDQDGHVK 145
Query: 454 WIKRLDISTPISMQLDNWXNDMXTCTFXF 540
L T + +L ++ D C+ F
Sbjct: 146 LNLALTTETNCNFELLHFPRDHSNCSLSF 174
>X55019-1|CAA38759.1| 517|Homo sapiens acetylcholine receptor delta
subunit protein.
Length = 517
Score = 46.4 bits (105), Expect = 1e-04
Identities = 34/134 (25%), Positives = 60/134 (44%), Gaps = 7/134 (5%)
Frame = +1
Query: 166 YDRESPP----DSKIVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEWG- 327
Y++E P + + V L L L + +++E E T+ ++ W D RL WNA E+G
Sbjct: 38 YNKELRPVAHKEESVDVALALTLSNLISLKEVEETLTTNVWIEHGWTDNRLKWNAEEFGN 97
Query: 328 CSTWLVSSERLWRPDVVL-LNAAATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDN 504
S + + +W P++VL N + Y+ V + G V W+ + + +
Sbjct: 98 ISVLRLPPDMVWLPEIVLENNNDGSFQISYSCNVLVYHYGFVYWLPPAIFRSSCPISVTY 157
Query: 505 WXNDMXTCTFXFGS 546
+ D C+ F S
Sbjct: 158 FPFDWQNCSLKFSS 171
>BC093925-1|AAH93925.1| 517|Homo sapiens cholinergic receptor,
nicotinic, delta protein.
Length = 517
Score = 46.4 bits (105), Expect = 1e-04
Identities = 34/134 (25%), Positives = 60/134 (44%), Gaps = 7/134 (5%)
Frame = +1
Query: 166 YDRESPP----DSKIVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEWG- 327
Y++E P + + V L L L + +++E E T+ ++ W D RL WNA E+G
Sbjct: 38 YNKELRPVAHKEESVDVALALTLSNLISLKEVEETLTTNVWIEHGWTDNRLKWNAEEFGN 97
Query: 328 CSTWLVSSERLWRPDVVL-LNAAATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDN 504
S + + +W P++VL N + Y+ V + G V W+ + + +
Sbjct: 98 ISVLRLPPDMVWLPEIVLENNNDGSFQISYSCNVLVYHYGFVYWLPPAIFRSSCPISVTY 157
Query: 505 WXNDMXTCTFXFGS 546
+ D C+ F S
Sbjct: 158 FPFDWQNCSLKFSS 171
>BC093923-1|AAH93923.1| 517|Homo sapiens cholinergic receptor,
nicotinic, delta protein.
Length = 517
Score = 46.4 bits (105), Expect = 1e-04
Identities = 34/134 (25%), Positives = 60/134 (44%), Gaps = 7/134 (5%)
Frame = +1
Query: 166 YDRESPP----DSKIVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEWG- 327
Y++E P + + V L L L + +++E E T+ ++ W D RL WNA E+G
Sbjct: 38 YNKELRPVAHKEESVDVALALTLSNLISLKEVEETLTTNVWIEHGWTDNRLKWNAEEFGN 97
Query: 328 CSTWLVSSERLWRPDVVL-LNAAATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDN 504
S + + +W P++VL N + Y+ V + G V W+ + + +
Sbjct: 98 ISVLRLPPDMVWLPEIVLENNNDGSFQISYSCNVLVYHYGFVYWLPPAIFRSSCPISVTY 157
Query: 505 WXNDMXTCTFXFGS 546
+ D C+ F S
Sbjct: 158 FPFDWQNCSLKFSS 171
>AC092165-2|AAY24102.1| 517|Homo sapiens unknown protein.
Length = 517
Score = 46.4 bits (105), Expect = 1e-04
Identities = 34/134 (25%), Positives = 60/134 (44%), Gaps = 7/134 (5%)
Frame = +1
Query: 166 YDRESPP----DSKIVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEWG- 327
Y++E P + + V L L L + +++E E T+ ++ W D RL WNA E+G
Sbjct: 38 YNKELRPVAHKEESVDVALALTLSNLISLKEVEETLTTNVWIEHGWTDNRLKWNAEEFGN 97
Query: 328 CSTWLVSSERLWRPDVVL-LNAAATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDN 504
S + + +W P++VL N + Y+ V + G V W+ + + +
Sbjct: 98 ISVLRLPPDMVWLPEIVLENNNDGSFQISYSCNVLVYHYGFVYWLPPAIFRSSCPISVTY 157
Query: 505 WXNDMXTCTFXFGS 546
+ D C+ F S
Sbjct: 158 FPFDWQNCSLKFSS 171
>AB223030-1|BAE19924.1| 411|Homo sapiens ligand-gated ion-channel
receptor L2 protein.
Length = 411
Score = 46.4 bits (105), Expect = 1e-04
Identities = 25/89 (28%), Positives = 41/89 (46%)
Frame = +1
Query: 274 LQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVS 453
L+++W+D RL+WN + E LW P + +L A D + +ARV +G V
Sbjct: 86 LRLSWLDTRLAWNTSAHPRHAITLPWESLWTPRLTILEALWVDWRDQSPQARVDQDGHVK 145
Query: 454 WIKRLDISTPISMQLDNWXNDMXTCTFXF 540
L T + +L ++ D C+ F
Sbjct: 146 LNLALATETNCNFELLHFPRDHSNCSLSF 174
>Z23141-1|CAA80672.1| 479|Homo sapiens cholinergic receptor,
nicotinic, alpha polypeptide 7 protein.
Length = 479
Score = 45.6 bits (103), Expect = 2e-04
Identities = 29/123 (23%), Positives = 53/123 (43%), Gaps = 3/123 (2%)
Frame = +1
Query: 274 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSNNGS 447
LQM+W D L WN E+ G T ++W+PD++L N+A + V+++G
Sbjct: 55 LQMSWTDHYLQWNVSEYPGVKTVRFPDGQIWKPDILLYNSADERFDATFHTNVLVNSSGH 114
Query: 448 VSWIKRLDISTPISMQLDNWXNDMXTCTFXFGSRMHNSDXXDFVI-DXXIYXMFXSXAWD 624
++ + + + + D+ C FGS + D + + I + WD
Sbjct: 115 CQYLPPGIFKSSCYIDVRWFPFDVQHCKLKFGSWSYGGWSLDLQMQEADISGYIPNGEWD 174
Query: 625 VTG 633
+ G
Sbjct: 175 LVG 177
>Y08420-1|CAA69697.1| 502|Homo sapiens nicotinic acetylcholine
receptor alpha7 subunit precursor protein.
Length = 502
Score = 45.6 bits (103), Expect = 2e-04
Identities = 29/123 (23%), Positives = 53/123 (43%), Gaps = 3/123 (2%)
Frame = +1
Query: 274 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSNNGS 447
LQM+W D L WN E+ G T ++W+PD++L N+A + V+++G
Sbjct: 78 LQMSWTDHYLQWNVSEYPGVKTVRFPDGQIWKPDILLYNSADERFDATFHTNVLVNSSGH 137
Query: 448 VSWIKRLDISTPISMQLDNWXNDMXTCTFXFGSRMHNSDXXDFVI-DXXIYXMFXSXAWD 624
++ + + + + D+ C FGS + D + + I + WD
Sbjct: 138 CQYLPPGIFKSSCYIDVRWFPFDVQHCKLKFGSWSYGGWSLDLQMQEADISGYIPNGEWD 197
Query: 625 VTG 633
+ G
Sbjct: 198 LVG 200
>X70297-1|CAA49778.1| 502|Homo sapiens neuronal nicotinic
acetylocholine receptor alpha-7 subunit protein.
Length = 502
Score = 45.6 bits (103), Expect = 2e-04
Identities = 29/123 (23%), Positives = 53/123 (43%), Gaps = 3/123 (2%)
Frame = +1
Query: 274 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSNNGS 447
LQM+W D L WN E+ G T ++W+PD++L N+A + V+++G
Sbjct: 78 LQMSWTDHYLQWNVSEYPGVKTVRFPDGQIWKPDILLYNSADERFDATFHTNVLVNSSGH 137
Query: 448 VSWIKRLDISTPISMQLDNWXNDMXTCTFXFGSRMHNSDXXDFVI-DXXIYXMFXSXAWD 624
++ + + + + D+ C FGS + D + + I + WD
Sbjct: 138 CQYLPPGIFKSSCYIDVRWFPFDVQHCKLKFGSWSYGGWSLDLQMQEADISGYIPNGEWD 197
Query: 625 VTG 633
+ G
Sbjct: 198 LVG 200
>U62436-1|AAB40114.1| 502|Homo sapiens nicotinic acetylcholine
receptor alpha7 subunit precursor protein.
Length = 502
Score = 45.6 bits (103), Expect = 2e-04
Identities = 29/123 (23%), Positives = 53/123 (43%), Gaps = 3/123 (2%)
Frame = +1
Query: 274 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSNNGS 447
LQM+W D L WN E+ G T ++W+PD++L N+A + V+++G
Sbjct: 78 LQMSWTDHYLQWNVSEYPGVKTVRFPDGQIWKPDILLYNSADERFDATFHTNVLVNSSGH 137
Query: 448 VSWIKRLDISTPISMQLDNWXNDMXTCTFXFGSRMHNSDXXDFVI-DXXIYXMFXSXAWD 624
++ + + + + D+ C FGS + D + + I + WD
Sbjct: 138 CQYLPPGIFKSSCYIDVRWFPFDVQHCKLKFGSWSYGGWSLDLQMQEADISGYIPNGEWD 197
Query: 625 VTG 633
+ G
Sbjct: 198 LVG 200
>L08485-1|AAA58490.1| 462|Homo sapiens GABA-benzodiazepine receptor
alpha-5-subunit protein.
Length = 462
Score = 45.6 bits (103), Expect = 2e-04
Identities = 39/168 (23%), Positives = 72/168 (42%), Gaps = 8/168 (4%)
Frame = +1
Query: 67 SXYRFSSLDAIASAAEC-ENATSLSLMIDSLLATYDRESPPD--SKIV-VNLTLHLRHAN 234
S + FS + + E +N T + ++D LL YD P +I V +++
Sbjct: 26 SHFGFSQMPTSSVKDETNDNITIFTRILDGLLDGYDNRLRPGLGERITQVRTDIYVTSFG 85
Query: 235 -IRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGD 411
+ ++E I + +W D+RL + + + ++W PD N + A +
Sbjct: 86 PVSDTEMEYTIDVFFRQSWKDERLRFKGPMQRLPLNNLLASKIWTPDTFFHNGKKSIAHN 145
Query: 412 YALR---ARVSNNGSVSWIKRLDISTPISMQLDNWXNDMXTCTFXFGS 546
R+ ++G++ + RL IS MQL+++ D C FGS
Sbjct: 146 MTTPNKLLRLEDDGTLLYTMRLTISAECPMQLEDFPMDAHACPLKFGS 193
>BT009830-1|AAP88832.1| 462|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 5 protein.
Length = 462
Score = 45.6 bits (103), Expect = 2e-04
Identities = 39/168 (23%), Positives = 72/168 (42%), Gaps = 8/168 (4%)
Frame = +1
Query: 67 SXYRFSSLDAIASAAEC-ENATSLSLMIDSLLATYDRESPPD--SKIV-VNLTLHLRHAN 234
S + FS + + E +N T + ++D LL YD P +I V +++
Sbjct: 26 SHFGFSQMPTSSVKDETNDNITIFTRILDGLLDGYDNRLRPGLGERITQVRTDIYVTSFG 85
Query: 235 -IRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGD 411
+ ++E I + +W D+RL + + + ++W PD N + A +
Sbjct: 86 PVSDTEMEYTIDVFFRQSWKDERLRFKGPMQRLPLNNLLASKIWTPDTFFHNGKKSIAHN 145
Query: 412 YALR---ARVSNNGSVSWIKRLDISTPISMQLDNWXNDMXTCTFXFGS 546
R+ ++G++ + RL IS MQL+++ D C FGS
Sbjct: 146 MTTPNKLLRLEDDGTLLYTMRLTISAECPMQLEDFPMDAHACPLKFGS 193
>BC113422-1|AAI13423.1| 462|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 5 protein.
Length = 462
Score = 45.6 bits (103), Expect = 2e-04
Identities = 39/168 (23%), Positives = 72/168 (42%), Gaps = 8/168 (4%)
Frame = +1
Query: 67 SXYRFSSLDAIASAAEC-ENATSLSLMIDSLLATYDRESPPD--SKIV-VNLTLHLRHAN 234
S + FS + + E +N T + ++D LL YD P +I V +++
Sbjct: 26 SHFGFSQMPTSSVKDETNDNITIFTRILDGLLDGYDNRLRPGLGERITQVRTDIYVTSFG 85
Query: 235 -IRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGD 411
+ ++E I + +W D+RL + + + ++W PD N + A +
Sbjct: 86 PVSDTEMEYTIDVFFRQSWKDERLRFKGPMQRLPLNNLLASKIWTPDTFFHNGKKSIAHN 145
Query: 412 YALR---ARVSNNGSVSWIKRLDISTPISMQLDNWXNDMXTCTFXFGS 546
R+ ++G++ + RL IS MQL+++ D C FGS
Sbjct: 146 MTTPNKLLRLEDDGTLLYTMRLTISAECPMQLEDFPMDAHACPLKFGS 193
>BC111979-1|AAI11980.1| 462|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 5, precursor protein.
Length = 462
Score = 45.6 bits (103), Expect = 2e-04
Identities = 39/168 (23%), Positives = 72/168 (42%), Gaps = 8/168 (4%)
Frame = +1
Query: 67 SXYRFSSLDAIASAAEC-ENATSLSLMIDSLLATYDRESPPD--SKIV-VNLTLHLRHAN 234
S + FS + + E +N T + ++D LL YD P +I V +++
Sbjct: 26 SHFGFSQMPTSSVKDETNDNITIFTRILDGLLDGYDNRLRPGLGERITQVRTDIYVTSFG 85
Query: 235 -IRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGD 411
+ ++E I + +W D+RL + + + ++W PD N + A +
Sbjct: 86 PVSDTEMEYTIDVFFRQSWKDERLRFKGPMQRLPLNNLLASKIWTPDTFFHNGKKSIAHN 145
Query: 412 YALR---ARVSNNGSVSWIKRLDISTPISMQLDNWXNDMXTCTFXFGS 546
R+ ++G++ + RL IS MQL+++ D C FGS
Sbjct: 146 MTTPNKLLRLEDDGTLLYTMRLTISAECPMQLEDFPMDAHACPLKFGS 193
>AJ586911-1|CAE52911.1| 502|Homo sapiens nicotinic acetylcholine
alpha-7 subunit protein.
Length = 502
Score = 45.6 bits (103), Expect = 2e-04
Identities = 29/123 (23%), Positives = 53/123 (43%), Gaps = 3/123 (2%)
Frame = +1
Query: 274 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSNNGS 447
LQM+W D L WN E+ G T ++W+PD++L N+A + V+++G
Sbjct: 78 LQMSWTDHYLQWNVSEYPGVKTVRFPDGQIWKPDILLYNSADERFDATFHTNVLVNSSGH 137
Query: 448 VSWIKRLDISTPISMQLDNWXNDMXTCTFXFGSRMHNSDXXDFVI-DXXIYXMFXSXAWD 624
++ + + + + D+ C FGS + D + + I + WD
Sbjct: 138 CQYLPPGIFKSSCYIDVRWFPFDVQHCKLKFGSWSYGGWSLDLQMQEADISGYIPNGEWD 197
Query: 625 VTG 633
+ G
Sbjct: 198 LVG 200
>U40583-1|AAA83561.1| 502|Homo sapiens alpha 7 neuronal nicotinic
acetylcholine receptor protein.
Length = 502
Score = 44.4 bits (100), Expect = 5e-04
Identities = 29/123 (23%), Positives = 52/123 (42%), Gaps = 3/123 (2%)
Frame = +1
Query: 274 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSNNGS 447
LQM+W D L WN E+ G T ++W+PD++L N+A + V+ +G
Sbjct: 78 LQMSWTDHYLQWNVSEYPGVKTVRFPDGQIWKPDILLYNSADERFDATFHTNVLVNPSGH 137
Query: 448 VSWIKRLDISTPISMQLDNWXNDMXTCTFXFGSRMHNSDXXDFVI-DXXIYXMFXSXAWD 624
++ + + + + D+ C FGS + D + + I + WD
Sbjct: 138 CQYLPPGIFKSSCYIDVRWFPFDVQHCKLKFGSWSYGGWSLDLQMQEADISGYIPNGEWD 197
Query: 625 VTG 633
+ G
Sbjct: 198 LVG 200
>AF385585-1|AAK68111.1| 502|Homo sapiens nicotinic cholinergic
receptor alpha 7 protein.
Length = 502
Score = 44.4 bits (100), Expect = 5e-04
Identities = 29/123 (23%), Positives = 52/123 (42%), Gaps = 3/123 (2%)
Frame = +1
Query: 274 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSNNGS 447
LQM+W D L WN E+ G T ++W+PD++L N+A + V+ +G
Sbjct: 78 LQMSWTDHYLQWNVSEYPGVKTVRFPDGQIWKPDILLYNSADERFDATFHTNVLVNPSGH 137
Query: 448 VSWIKRLDISTPISMQLDNWXNDMXTCTFXFGSRMHNSDXXDFVI-DXXIYXMFXSXAWD 624
++ + + + + D+ C FGS + D + + I + WD
Sbjct: 138 CQYLPPGIFKSSCYIDVRWFPFDVQHCKLKFGSWSYGGWSLDLQMQEADISGYIPNGEWD 197
Query: 625 VTG 633
+ G
Sbjct: 198 LVG 200
>BC028629-1|AAH28629.1| 492|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 3 protein.
Length = 492
Score = 43.6 bits (98), Expect = 0.001
Identities = 33/150 (22%), Positives = 64/150 (42%), Gaps = 7/150 (4%)
Frame = +1
Query: 118 ENATSLSLMIDSLLATYDRESPP---DSKIVVNLTLHLRHAN-IRESESTVRILADLQMN 285
+N T + ++D LL YD P D+ V +++ + +++ I +
Sbjct: 62 DNITIFTRILDRLLDGYDNRLRPGLGDAVTEVKTDIYVTSFGPVSDTDMEYTIDVFFRQT 121
Query: 286 WIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSW 456
W D+RL ++ + + ++W PD N + A + R+ +NG++ +
Sbjct: 122 WHDERLKFDGPMKILPLNNLLASKIWTPDTFFHNGKKSVAHNMTTPNKLLRLVDNGTLPY 181
Query: 457 IKRLDISTPISMQLDNWXNDMXTCTFXFGS 546
RL I M L+++ D+ C FGS
Sbjct: 182 TMRLTIHAECPMHLEDFPMDVHACPLKFGS 211
>S62908-1|AAB27279.1| 492|Homo sapiens gamma-aminobutyric acidA
receptor alpha 3 subunit protein.
Length = 492
Score = 43.2 bits (97), Expect = 0.001
Identities = 33/150 (22%), Positives = 64/150 (42%), Gaps = 7/150 (4%)
Frame = +1
Query: 118 ENATSLSLMIDSLLATYDRESPP---DSKIVVNLTLHLRHAN-IRESESTVRILADLQMN 285
+N T + ++D LL YD P D+ V +++ + +++ I +
Sbjct: 62 DNITIFTRILDRLLDGYDNRLRPGLGDAVTEVKTDIYVTSFGPVSDTDMEYTIDVFFRQT 121
Query: 286 WIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSW 456
W D+RL ++ + + ++W PD N + A + R+ +NG++ +
Sbjct: 122 WHDERLKFDGPMKILPLNNLLASKIWTPDTFFHNGKKSVAHNMTTPNKLLRLVDNGTLLY 181
Query: 457 IKRLDISTPISMQLDNWXNDMXTCTFXFGS 546
RL I M L+++ D+ C FGS
Sbjct: 182 TMRLTIHAECPMHLEDFPMDVHACPLKFGS 211
>AF166361-1|AAG12455.1| 492|Homo sapiens GABA receptor subunit
alpha 3 protein.
Length = 492
Score = 43.2 bits (97), Expect = 0.001
Identities = 33/150 (22%), Positives = 64/150 (42%), Gaps = 7/150 (4%)
Frame = +1
Query: 118 ENATSLSLMIDSLLATYDRESPP---DSKIVVNLTLHLRHAN-IRESESTVRILADLQMN 285
+N T + ++D LL YD P D+ V +++ + +++ I +
Sbjct: 62 DNITIFTRILDRLLDGYDNRLRPGLGDAVTEVKTDIYVTSFGPVSDTDMEYTIDVFFRQT 121
Query: 286 WIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSW 456
W D+RL ++ + + ++W PD N + A + R+ +NG++ +
Sbjct: 122 WHDERLKFDGPMKILPLNNLLASKIWTPDTFFHNGKKSVAHNMTTPNKLLRLVDNGTLLY 181
Query: 457 IKRLDISTPISMQLDNWXNDMXTCTFXFGS 546
RL I M L+++ D+ C FGS
Sbjct: 182 TMRLTIHAECPMHLEDFPMDVHACPLKFGS 211
>U77731-2|AAB38273.1| 360|Homo sapiens glycine receptor alpha 2B
subunit protein.
Length = 360
Score = 42.3 bits (95), Expect = 0.002
Identities = 36/135 (26%), Positives = 57/135 (42%), Gaps = 8/135 (5%)
Frame = +1
Query: 166 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 333
YD P+ K VN+T ++ +I E+ R+ L+ W D RL+++
Sbjct: 58 YDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDSRLAYSEYPDDSL 117
Query: 334 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLD 501
S + +W+PD+ N D R+S NG V + RL ++ M L
Sbjct: 118 DLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLK 177
Query: 502 NWXNDMXTCTFXFGS 546
N+ D+ TCT S
Sbjct: 178 NFPMDVQTCTMQLES 192
>CR450343-1|CAG29339.1| 452|Homo sapiens GLRA2 protein.
Length = 452
Score = 42.3 bits (95), Expect = 0.002
Identities = 36/135 (26%), Positives = 57/135 (42%), Gaps = 8/135 (5%)
Frame = +1
Query: 166 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 333
YD P+ K VN+T ++ +I E+ R+ L+ W D RL+++
Sbjct: 58 YDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDSRLAYSEYPDDSL 117
Query: 334 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLD 501
S + +W+PD+ N D R+S NG V + RL ++ M L
Sbjct: 118 DLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLK 177
Query: 502 NWXNDMXTCTFXFGS 546
N+ D+ TCT S
Sbjct: 178 NFPMDVQTCTMQLES 192
>AY437084-1|AAR87843.1| 452|Homo sapiens glycine receptor alpha2
subunit B protein.
Length = 452
Score = 42.3 bits (95), Expect = 0.002
Identities = 36/135 (26%), Positives = 57/135 (42%), Gaps = 8/135 (5%)
Frame = +1
Query: 166 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 333
YD P+ K VN+T ++ +I E+ R+ L+ W D RL+++
Sbjct: 58 YDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDSRLAYSEYPDDSL 117
Query: 334 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLD 501
S + +W+PD+ N D R+S NG V + RL ++ M L
Sbjct: 118 DLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLK 177
Query: 502 NWXNDMXTCTFXFGS 546
N+ D+ TCT S
Sbjct: 178 NFPMDVQTCTMQLES 192
>X52008-1|CAA36257.1| 452|Homo sapiens inhibitory glycine receptor
protein.
Length = 452
Score = 41.9 bits (94), Expect = 0.003
Identities = 35/135 (25%), Positives = 57/135 (42%), Gaps = 8/135 (5%)
Frame = +1
Query: 166 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 333
YD P+ K VN+T ++ ++ E+ R+ L+ W D RL+++
Sbjct: 58 YDARIRPNFKGPPVNVTCNIFINSFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPDDSL 117
Query: 334 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLD 501
S + +W+PD+ N D R+S NG V + RL ++ M L
Sbjct: 118 DLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLK 177
Query: 502 NWXNDMXTCTFXFGS 546
N+ D+ TCT S
Sbjct: 178 NFPMDVQTCTMQLES 192
>U77731-1|AAB38272.1| 360|Homo sapiens glycine receptor alpha 2
subunit protein.
Length = 360
Score = 41.9 bits (94), Expect = 0.003
Identities = 35/135 (25%), Positives = 57/135 (42%), Gaps = 8/135 (5%)
Frame = +1
Query: 166 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 333
YD P+ K VN+T ++ ++ E+ R+ L+ W D RL+++
Sbjct: 58 YDARIRPNFKGPPVNVTCNIFINSFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPDDSL 117
Query: 334 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLD 501
S + +W+PD+ N D R+S NG V + RL ++ M L
Sbjct: 118 DLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLK 177
Query: 502 NWXNDMXTCTFXFGS 546
N+ D+ TCT S
Sbjct: 178 NFPMDVQTCTMQLES 192
>M59216-1|AAA35862.1| 474|Homo sapiens gamma-aminobutyric acid
receptor beta-1 subunit protein.
Length = 474
Score = 41.9 bits (94), Expect = 0.003
Identities = 37/165 (22%), Positives = 67/165 (40%), Gaps = 7/165 (4%)
Frame = +1
Query: 103 SAAECENATSLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESESTVRILA 270
S E N + + +D LL YD PD + V + + + + + E +
Sbjct: 27 STNEPSNMSYVKETVDRLLKGYDIRLRPDFGGPPVDVGMRIDVASIDMVSEVNMDYTLTM 86
Query: 271 DLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNN 441
Q +W DKRLS++ + +++LW PD LN + ++ R+ +
Sbjct: 87 YFQQSWKDKRLSYSGIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPD 146
Query: 442 GSVSWIKRLDISTPISMQLDNWXNDMXTCTFXFGSRMHNSDXXDF 576
G+V + R+ + M L + D CT S + +D +F
Sbjct: 147 GTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEF 191
>BC032864-1|AAH32864.1| 452|Homo sapiens glycine receptor, alpha 2
protein.
Length = 452
Score = 41.9 bits (94), Expect = 0.003
Identities = 35/135 (25%), Positives = 57/135 (42%), Gaps = 8/135 (5%)
Frame = +1
Query: 166 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 333
YD P+ K VN+T ++ ++ E+ R+ L+ W D RL+++
Sbjct: 58 YDARIRPNFKGPPVNVTCNIFINSFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPDDSL 117
Query: 334 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLD 501
S + +W+PD+ N D R+S NG V + RL ++ M L
Sbjct: 118 DLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLK 177
Query: 502 NWXNDMXTCTFXFGS 546
N+ D+ TCT S
Sbjct: 178 NFPMDVQTCTMQLES 192
>AY437083-1|AAR87842.1| 452|Homo sapiens glycine receptor alpha2
subunit A protein.
Length = 452
Score = 41.9 bits (94), Expect = 0.003
Identities = 35/135 (25%), Positives = 57/135 (42%), Gaps = 8/135 (5%)
Frame = +1
Query: 166 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 333
YD P+ K VN+T ++ ++ E+ R+ L+ W D RL+++
Sbjct: 58 YDARIRPNFKGPPVNVTCNIFINSFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPDDSL 117
Query: 334 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLD 501
S + +W+PD+ N D R+S NG V + RL ++ M L
Sbjct: 118 DLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLK 177
Query: 502 NWXNDMXTCTFXFGS 546
N+ D+ TCT S
Sbjct: 178 NFPMDVQTCTMQLES 192
>AF053495-1|AAC35290.1| 452|Homo sapiens glycine receptor alpha 2
subunit protein.
Length = 452
Score = 41.9 bits (94), Expect = 0.003
Identities = 35/135 (25%), Positives = 57/135 (42%), Gaps = 8/135 (5%)
Frame = +1
Query: 166 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 333
YD P+ K VN+T ++ ++ E+ R+ L+ W D RL+++
Sbjct: 58 YDARIRPNFKGPPVNVTCNIFINSFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPDDSL 117
Query: 334 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLD 501
S + +W+PD+ N D R+S NG V + RL ++ M L
Sbjct: 118 DLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLK 177
Query: 502 NWXNDMXTCTFXFGS 546
N+ D+ TCT S
Sbjct: 178 NFPMDVQTCTMQLES 192
>X14767-1|CAA32875.1| 474|Homo sapiens GABA-A receptor beta 1
subunit protein.
Length = 474
Score = 41.1 bits (92), Expect = 0.005
Identities = 37/165 (22%), Positives = 66/165 (40%), Gaps = 7/165 (4%)
Frame = +1
Query: 103 SAAECENATSLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESESTVRILA 270
S E N + +D LL YD PD + V + + + + + E +
Sbjct: 27 STNEPSNMPYVKETVDRLLKGYDIRLRPDFGGPPVDVGMRIDVASIDMVSEVNMDYTLTM 86
Query: 271 DLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNN 441
Q +W DKRLS++ + +++LW PD LN + ++ R+ +
Sbjct: 87 YFQQSWKDKRLSYSGIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPD 146
Query: 442 GSVSWIKRLDISTPISMQLDNWXNDMXTCTFXFGSRMHNSDXXDF 576
G+V + R+ + M L + D CT S + +D +F
Sbjct: 147 GTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEF 191
>S81944-1|AAB36480.1| 453|Homo sapiens gamma-aminobutyric acid type
A receptor alpha 6 subunit protein.
Length = 453
Score = 41.1 bits (92), Expect = 0.005
Identities = 33/146 (22%), Positives = 60/146 (41%), Gaps = 7/146 (4%)
Frame = +1
Query: 130 SLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESESTVRILADLQMNWIDK 297
++S ++D+LL YD P + V +++ + + E + + W D+
Sbjct: 31 NVSRILDNLLEGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTDE 90
Query: 298 RLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRA---RVSNNGSVSWIKRL 468
RL + S + ++W PD N + A + R+ NG++ + RL
Sbjct: 91 RLKFGGPTEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTMRL 150
Query: 469 DISTPISMQLDNWXNDMXTCTFXFGS 546
I+ M+L N+ D C FGS
Sbjct: 151 TINADCPMRLVNFPMDGHACPLKFGS 176
>BC109211-1|AAI09212.1| 632|Homo sapiens gamma-aminobutyric acid
(GABA) receptor, theta protein.
Length = 632
Score = 41.1 bits (92), Expect = 0.005
Identities = 33/145 (22%), Positives = 58/145 (40%), Gaps = 7/145 (4%)
Frame = +1
Query: 115 CENATSLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESESTVRILADLQM 282
C N + ++D +L+ YD P+ + + V +++++ I E I
Sbjct: 53 CANEAVVQKILDRVLSRYDVRLRPNFGGAPVPVRISIYVTSIEQISEMNMDYTITMFFHQ 112
Query: 283 NWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSN---NGSVS 453
W D RL++ + E+LW PD LN+ D + RV +G+V
Sbjct: 113 TWKDSRLAYYETTLNLTLDYRMHEKLWVPDCYFLNSKDAFVHDVTVENRVFQLHPDGTVR 172
Query: 454 WIKRLDISTPISMQLDNWXNDMXTC 528
+ RL + S+ L + D C
Sbjct: 173 YGIRLTTTAACSLDLHKFPMDKQAC 197
>BC109210-1|AAI09211.1| 632|Homo sapiens gamma-aminobutyric acid
(GABA) receptor, theta protein.
Length = 632
Score = 41.1 bits (92), Expect = 0.005
Identities = 33/145 (22%), Positives = 58/145 (40%), Gaps = 7/145 (4%)
Frame = +1
Query: 115 CENATSLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESESTVRILADLQM 282
C N + ++D +L+ YD P+ + + V +++++ I E I
Sbjct: 53 CANEAVVQKILDRVLSRYDVRLRPNFGGAPVPVRISIYVTSIEQISEMNMDYTITMFFHQ 112
Query: 283 NWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSN---NGSVS 453
W D RL++ + E+LW PD LN+ D + RV +G+V
Sbjct: 113 TWKDSRLAYYETTLNLTLDYRMHEKLWVPDCYFLNSKDAFVHDVTVENRVFQLHPDGTVR 172
Query: 454 WIKRLDISTPISMQLDNWXNDMXTC 528
+ RL + S+ L + D C
Sbjct: 173 YGIRLTTTAACSLDLHKFPMDKQAC 197
>BC099641-1|AAH99641.1| 453|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 6 protein.
Length = 453
Score = 41.1 bits (92), Expect = 0.005
Identities = 33/146 (22%), Positives = 60/146 (41%), Gaps = 7/146 (4%)
Frame = +1
Query: 130 SLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESESTVRILADLQMNWIDK 297
++S ++D+LL YD P + V +++ + + E + + W D+
Sbjct: 31 NVSRILDNLLEGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTDE 90
Query: 298 RLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRA---RVSNNGSVSWIKRL 468
RL + S + ++W PD N + A + R+ NG++ + RL
Sbjct: 91 RLKFGGPTEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTMRL 150
Query: 469 DISTPISMQLDNWXNDMXTCTFXFGS 546
I+ M+L N+ D C FGS
Sbjct: 151 TINADCPMRLVNFPMDGHACPLKFGS 176
>BC099640-1|AAH99640.1| 453|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 6 protein.
Length = 453
Score = 41.1 bits (92), Expect = 0.005
Identities = 33/146 (22%), Positives = 60/146 (41%), Gaps = 7/146 (4%)
Frame = +1
Query: 130 SLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESESTVRILADLQMNWIDK 297
++S ++D+LL YD P + V +++ + + E + + W D+
Sbjct: 31 NVSRILDNLLEGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTDE 90
Query: 298 RLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRA---RVSNNGSVSWIKRL 468
RL + S + ++W PD N + A + R+ NG++ + RL
Sbjct: 91 RLKFGGPTEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTMRL 150
Query: 469 DISTPISMQLDNWXNDMXTCTFXFGS 546
I+ M+L N+ D C FGS
Sbjct: 151 TINADCPMRLVNFPMDGHACPLKFGS 176
>BC096242-1|AAH96242.1| 453|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 6 protein.
Length = 453
Score = 41.1 bits (92), Expect = 0.005
Identities = 33/146 (22%), Positives = 60/146 (41%), Gaps = 7/146 (4%)
Frame = +1
Query: 130 SLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESESTVRILADLQMNWIDK 297
++S ++D+LL YD P + V +++ + + E + + W D+
Sbjct: 31 NVSRILDNLLEGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTDE 90
Query: 298 RLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRA---RVSNNGSVSWIKRL 468
RL + S + ++W PD N + A + R+ NG++ + RL
Sbjct: 91 RLKFGGPTEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTMRL 150
Query: 469 DISTPISMQLDNWXNDMXTCTFXFGS 546
I+ M+L N+ D C FGS
Sbjct: 151 TINADCPMRLVNFPMDGHACPLKFGS 176
>BC096241-1|AAH96241.1| 453|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 6 protein.
Length = 453
Score = 41.1 bits (92), Expect = 0.005
Identities = 33/146 (22%), Positives = 60/146 (41%), Gaps = 7/146 (4%)
Frame = +1
Query: 130 SLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESESTVRILADLQMNWIDK 297
++S ++D+LL YD P + V +++ + + E + + W D+
Sbjct: 31 NVSRILDNLLEGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTDE 90
Query: 298 RLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRA---RVSNNGSVSWIKRL 468
RL + S + ++W PD N + A + R+ NG++ + RL
Sbjct: 91 RLKFGGPTEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTMRL 150
Query: 469 DISTPISMQLDNWXNDMXTCTFXFGS 546
I+ M+L N+ D C FGS
Sbjct: 151 TINADCPMRLVNFPMDGHACPLKFGS 176
>AF189259-1|AAF70380.1| 632|Homo sapiens GABA-A receptor theta
subunit protein.
Length = 632
Score = 41.1 bits (92), Expect = 0.005
Identities = 33/145 (22%), Positives = 58/145 (40%), Gaps = 7/145 (4%)
Frame = +1
Query: 115 CENATSLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESESTVRILADLQM 282
C N + ++D +L+ YD P+ + + V +++++ I E I
Sbjct: 53 CANEAVVQKILDRVLSRYDVRLRPNFGGAPVPVRISIYVTSIEQISEMNMDYTITMFFHQ 112
Query: 283 NWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSN---NGSVS 453
W D RL++ + E+LW PD LN+ D + RV +G+V
Sbjct: 113 TWKDSRLAYYETTLNLTLDYRMHEKLWVPDCYFLNSKDAFVHDVTVENRVFQLHPDGTVR 172
Query: 454 WIKRLDISTPISMQLDNWXNDMXTC 528
+ RL + S+ L + D C
Sbjct: 173 YGIRLTTTAACSLDLHKFPMDKQAC 197
>AF144648-1|AAD51172.1| 627|Homo sapiens GABA-A receptor theta
protein.
Length = 627
Score = 41.1 bits (92), Expect = 0.005
Identities = 33/145 (22%), Positives = 58/145 (40%), Gaps = 7/145 (4%)
Frame = +1
Query: 115 CENATSLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESESTVRILADLQM 282
C N + ++D +L+ YD P+ + + V +++++ I E I
Sbjct: 48 CANEAVVQKILDRVLSRYDVRLRPNFGGAPVPVRISIYVTSIEQISEMNMDYTITMFFHQ 107
Query: 283 NWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSN---NGSVS 453
W D RL++ + E+LW PD LN+ D + RV +G+V
Sbjct: 108 TWKDSRLAYYETTLNLTLDYRMHEKLWVPDCYFLNSKDAFVHDVTVENRVFQLHPDGTVR 167
Query: 454 WIKRLDISTPISMQLDNWXNDMXTC 528
+ RL + S+ L + D C
Sbjct: 168 YGIRLTTTAACSLDLHKFPMDKQAC 192
>X52009-1|CAA36258.1| 449|Homo sapiens inhibitory glycine receptor
protein.
Length = 449
Score = 39.9 bits (89), Expect = 0.012
Identities = 43/164 (26%), Positives = 70/164 (42%), Gaps = 14/164 (8%)
Frame = +1
Query: 79 FSSLDAIASAAECENAT---SLSLMIDSLLAT---YDRESPPDSK-IVVNLTLHL---RH 228
F SL A A +AT S S +D L+ YD P+ K VN++ ++
Sbjct: 17 FFSLAASKEAEAARSATKPMSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVSCNIFINSF 76
Query: 229 ANIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERLWRPDVVLLNAAATTA 405
+I E+ R+ L+ W D RL++N S + +W+PD+ N
Sbjct: 77 GSIAETTMDYRVNIFLRQQWNDPRLAYNEYPDDSLDLDPSMLDSIWKPDLFFANEKGAHF 136
Query: 406 GDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWXNDMXTC 528
+ R+S NG+V + R+ ++ M L N+ D+ TC
Sbjct: 137 HEITTDNKLLRISRNGNVLYSIRITLTLACPMDLKNFPMDVQTC 180
>BC033801-1|AAH33801.1| 452|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, delta protein.
Length = 452
Score = 39.9 bits (89), Expect = 0.012
Identities = 36/147 (24%), Positives = 60/147 (40%), Gaps = 7/147 (4%)
Frame = +1
Query: 145 IDSLLATYDRESPPD-SKIVVNLTLHLRHANI---RESESTVRILADLQMNWIDKRLSWN 312
+D L+A Y R P VN+ L L A+I E+ + L +W D RLS+N
Sbjct: 44 LDGLIAGYARNFRPGIGGPPVNVALALEVASIDHISEANMEYTMTVFLHQSWRDSRLSYN 103
Query: 313 AGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTP 483
++LW PD ++NA + D + R+ +G + + R+ +
Sbjct: 104 HTNETLGLDSRFVDKLWLPDTFIVNAKSAWFHDVTVENKLIRLQPDGVILYSIRITSTVA 163
Query: 484 ISMQLDNWXNDMXTCTFXFGSRMHNSD 564
M L + D C S ++S+
Sbjct: 164 CDMDLAKYPMDEQECMLDLESYGYSSE 190
>AL391845-4|CAI15436.1| 452|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, delta protein.
Length = 452
Score = 39.9 bits (89), Expect = 0.012
Identities = 36/147 (24%), Positives = 60/147 (40%), Gaps = 7/147 (4%)
Frame = +1
Query: 145 IDSLLATYDRESPPD-SKIVVNLTLHLRHANI---RESESTVRILADLQMNWIDKRLSWN 312
+D L+A Y R P VN+ L L A+I E+ + L +W D RLS+N
Sbjct: 44 LDGLIAGYARNFRPGIGGPPVNVALALEVASIDHISEANMEYTMTVFLHQSWRDSRLSYN 103
Query: 313 AGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTP 483
++LW PD ++NA + D + R+ +G + + R+ +
Sbjct: 104 HTNETLGLDSRFVDKLWLPDTFIVNAKSAWFHDVTVENKLIRLQPDGVILYSIRITSTVA 163
Query: 484 ISMQLDNWXNDMXTCTFXFGSRMHNSD 564
M L + D C S ++S+
Sbjct: 164 CDMDLAKYPMDEQECMLDLESYGYSSE 190
>AF016917-1|AAB70007.1| 452|Homo sapiens GABA-A receptor delta
subunit protein.
Length = 452
Score = 39.9 bits (89), Expect = 0.012
Identities = 36/147 (24%), Positives = 60/147 (40%), Gaps = 7/147 (4%)
Frame = +1
Query: 145 IDSLLATYDRESPPD-SKIVVNLTLHLRHANI---RESESTVRILADLQMNWIDKRLSWN 312
+D L+A Y R P VN+ L L A+I E+ + L +W D RLS+N
Sbjct: 44 LDGLIAGYARNFRPGIGGPPVNVALALEVASIDHISEANMEYTMTVFLHQSWRDSRLSYN 103
Query: 313 AGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTP 483
++LW PD ++NA + D + R+ +G + + R+ +
Sbjct: 104 HTNETLGLDSRFVDKLWLPDTFIVNAKSAWFHDVTVENKLIRLQPDGVILYSIRITSTVA 163
Query: 484 ISMQLDNWXNDMXTCTFXFGSRMHNSD 564
M L + D C S ++S+
Sbjct: 164 CDMDLAKYPMDEQECMLDLESYGYSSE 190
>U30461-1|AAB52519.1| 554|Homo sapiens GABAA receptor subunit
alpha4 protein.
Length = 554
Score = 39.1 bits (87), Expect = 0.020
Identities = 27/105 (25%), Positives = 45/105 (42%), Gaps = 3/105 (2%)
Frame = +1
Query: 241 ESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYAL 420
E E T+ + + WIDKRL ++ + ++W PD N + + +
Sbjct: 90 EMEYTMDVF--FRQTWIDKRLKYDGPIEILRLNNMMVTKVWTPDTFFRNGKKSVSHNMTA 147
Query: 421 RA---RVSNNGSVSWIKRLDISTPISMQLDNWXNDMXTCTFXFGS 546
R+ NG++ + RL IS M+L ++ D C FGS
Sbjct: 148 PNKLFRIMRNGTILYTMRLTISAECPMRLVDFPMDGHACPLKFGS 192
>BC035055-1|AAH35055.1| 554|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 4 protein.
Length = 554
Score = 39.1 bits (87), Expect = 0.020
Identities = 27/105 (25%), Positives = 45/105 (42%), Gaps = 3/105 (2%)
Frame = +1
Query: 241 ESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYAL 420
E E T+ + + WIDKRL ++ + ++W PD N + + +
Sbjct: 90 EMEYTMDVF--FRQTWIDKRLKYDGPIEILRLNNMMVTKVWTPDTFFRNGKKSVSHNMTA 147
Query: 421 RA---RVSNNGSVSWIKRLDISTPISMQLDNWXNDMXTCTFXFGS 546
R+ NG++ + RL IS M+L ++ D C FGS
Sbjct: 148 PNKLFRIMRNGTILYTMRLTISAECPMRLVDFPMDGHACPLKFGS 192
>U95367-1|AAC51357.1| 440|Homo sapiens GABA-A receptor pi subunit
protein.
Length = 440
Score = 38.3 bits (85), Expect = 0.036
Identities = 38/164 (23%), Positives = 73/164 (44%), Gaps = 9/164 (5%)
Frame = +1
Query: 112 ECENATSLSLM-IDSLLATYDRESPPD---SKIVVNLTLHLRH-ANIRESESTVRILADL 276
E + LSL ++L A Y++ P+ + + LTL + ++I ES L
Sbjct: 29 EVGRSDKLSLPGFENLTAGYNKFLRPNFGGEPVQIALTLDIASISSISESNMDYTATIYL 88
Query: 277 QMNWIDKRLSWNAGE-WGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNG 444
+ W+D+RL + + + LV E LW PD ++ + + + + R+ +NG
Sbjct: 89 RQRWMDQRLVFEGNKSFTLDARLV--EFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNG 146
Query: 445 SVSWIKRLDISTPISMQLDNWXNDMXTCTFXFGSRMHNSDXXDF 576
+V + R+ + +M L + D TC S ++ + +F
Sbjct: 147 TVLYALRITTTVACNMDLSKYPMDTQTCKLQLESWGYDGNDVEF 190
>BC109106-1|AAI09107.1| 440|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, pi protein.
Length = 440
Score = 38.3 bits (85), Expect = 0.036
Identities = 38/164 (23%), Positives = 73/164 (44%), Gaps = 9/164 (5%)
Frame = +1
Query: 112 ECENATSLSLM-IDSLLATYDRESPPD---SKIVVNLTLHLRH-ANIRESESTVRILADL 276
E + LSL ++L A Y++ P+ + + LTL + ++I ES L
Sbjct: 29 EVGRSDKLSLPGFENLTAGYNKFLRPNFGGEPVQIALTLDIASISSISESNMDYTATIYL 88
Query: 277 QMNWIDKRLSWNAGE-WGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNG 444
+ W+D+RL + + + LV E LW PD ++ + + + + R+ +NG
Sbjct: 89 RQRWMDQRLVFEGNKSFTLDARLV--EFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNG 146
Query: 445 SVSWIKRLDISTPISMQLDNWXNDMXTCTFXFGSRMHNSDXXDF 576
+V + R+ + +M L + D TC S ++ + +F
Sbjct: 147 TVLYALRITTTVACNMDLSKYPMDTQTCKLQLESWGYDGNDVEF 190
>BC109105-1|AAI09106.1| 440|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, pi protein.
Length = 440
Score = 38.3 bits (85), Expect = 0.036
Identities = 38/164 (23%), Positives = 73/164 (44%), Gaps = 9/164 (5%)
Frame = +1
Query: 112 ECENATSLSLM-IDSLLATYDRESPPD---SKIVVNLTLHLRH-ANIRESESTVRILADL 276
E + LSL ++L A Y++ P+ + + LTL + ++I ES L
Sbjct: 29 EVGRSDKLSLPGFENLTAGYNKFLRPNFGGEPVQIALTLDIASISSISESNMDYTATIYL 88
Query: 277 QMNWIDKRLSWNAGE-WGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNG 444
+ W+D+RL + + + LV E LW PD ++ + + + + R+ +NG
Sbjct: 89 RQRWMDQRLVFEGNKSFTLDARLV--EFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNG 146
Query: 445 SVSWIKRLDISTPISMQLDNWXNDMXTCTFXFGSRMHNSDXXDF 576
+V + R+ + +M L + D TC S ++ + +F
Sbjct: 147 TVLYALRITTTVACNMDLSKYPMDTQTCKLQLESWGYDGNDVEF 190
>BC074865-1|AAH74865.1| 440|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, pi protein.
Length = 440
Score = 38.3 bits (85), Expect = 0.036
Identities = 38/164 (23%), Positives = 73/164 (44%), Gaps = 9/164 (5%)
Frame = +1
Query: 112 ECENATSLSLM-IDSLLATYDRESPPD---SKIVVNLTLHLRH-ANIRESESTVRILADL 276
E + LSL ++L A Y++ P+ + + LTL + ++I ES L
Sbjct: 29 EVGRSDKLSLPGFENLTAGYNKFLRPNFGGEPVQIALTLDIASISSISESNMDYTATIYL 88
Query: 277 QMNWIDKRLSWNAGE-WGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNG 444
+ W+D+RL + + + LV E LW PD ++ + + + + R+ +NG
Sbjct: 89 RQRWMDQRLVFEGNKSFTLDARLV--EFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNG 146
Query: 445 SVSWIKRLDISTPISMQLDNWXNDMXTCTFXFGSRMHNSDXXDF 576
+V + R+ + +M L + D TC S ++ + +F
Sbjct: 147 TVLYALRITTTVACNMDLSKYPMDTQTCKLQLESWGYDGNDVEF 190
>BC074810-1|AAH74810.1| 440|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, pi protein.
Length = 440
Score = 38.3 bits (85), Expect = 0.036
Identities = 38/164 (23%), Positives = 73/164 (44%), Gaps = 9/164 (5%)
Frame = +1
Query: 112 ECENATSLSLM-IDSLLATYDRESPPD---SKIVVNLTLHLRH-ANIRESESTVRILADL 276
E + LSL ++L A Y++ P+ + + LTL + ++I ES L
Sbjct: 29 EVGRSDKLSLPGFENLTAGYNKFLRPNFGGEPVQIALTLDIASISSISESNMDYTATIYL 88
Query: 277 QMNWIDKRLSWNAGE-WGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNG 444
+ W+D+RL + + + LV E LW PD ++ + + + + R+ +NG
Sbjct: 89 RQRWMDQRLVFEGNKSFTLDARLV--EFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNG 146
Query: 445 SVSWIKRLDISTPISMQLDNWXNDMXTCTFXFGSRMHNSDXXDF 576
+V + R+ + +M L + D TC S ++ + +F
Sbjct: 147 TVLYALRITTTVACNMDLSKYPMDTQTCKLQLESWGYDGNDVEF 190
>AF009702-1|AAC24194.1| 440|Homo sapiens GABA-A receptor pi subunit
protein.
Length = 440
Score = 38.3 bits (85), Expect = 0.036
Identities = 38/164 (23%), Positives = 73/164 (44%), Gaps = 9/164 (5%)
Frame = +1
Query: 112 ECENATSLSLM-IDSLLATYDRESPPD---SKIVVNLTLHLRH-ANIRESESTVRILADL 276
E + LSL ++L A Y++ P+ + + LTL + ++I ES L
Sbjct: 29 EVGRSDKLSLPGFENLTAGYNKFLRPNFGGEPVQIALTLDIASISSISESNMDYTATIYL 88
Query: 277 QMNWIDKRLSWNAGE-WGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNG 444
+ W+D+RL + + + LV E LW PD ++ + + + + R+ +NG
Sbjct: 89 RQRWMDQRLVFEGNKSFTLDARLV--EFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNG 146
Query: 445 SVSWIKRLDISTPISMQLDNWXNDMXTCTFXFGSRMHNSDXXDF 576
+V + R+ + +M L + D TC S ++ + +F
Sbjct: 147 TVLYALRITTTVACNMDLSKYPMDTQTCKLQLESWGYDGNDVEF 190
>BC114947-1|AAI14948.1| 457|Homo sapiens GLRA1 protein protein.
Length = 457
Score = 37.5 bits (83), Expect = 0.062
Identities = 42/164 (25%), Positives = 69/164 (42%), Gaps = 14/164 (8%)
Frame = +1
Query: 79 FSSLDAIASAAECENAT---SLSLMIDSLLAT---YDRESPPDSK-IVVNLTLHL---RH 228
F SL A A +A S S +D L+ YD P+ K VN++ ++
Sbjct: 17 FFSLAASKEAEAARSAPKPMSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVSCNIFINSF 76
Query: 229 ANIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERLWRPDVVLLNAAATTA 405
+I E+ R+ L+ W D RL++N S + +W+PD+ N
Sbjct: 77 GSIAETTMDYRVNIFLRQQWNDPRLAYNEYPDDSLDLDPSMLDSIWKPDLFFANEKGAHF 136
Query: 406 GDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWXNDMXTC 528
+ R+S NG+V + R+ ++ M L N+ D+ TC
Sbjct: 137 HEITTDNKLLRISRNGNVLYSIRITLTLACPMDLKNFPMDVQTC 180
>BC074980-1|AAH74980.1| 449|Homo sapiens glycine receptor, alpha 1
(startle disease/hyperekplexia) protein.
Length = 449
Score = 37.5 bits (83), Expect = 0.062
Identities = 42/164 (25%), Positives = 69/164 (42%), Gaps = 14/164 (8%)
Frame = +1
Query: 79 FSSLDAIASAAECENAT---SLSLMIDSLLAT---YDRESPPDSK-IVVNLTLHL---RH 228
F SL A A +A S S +D L+ YD P+ K VN++ ++
Sbjct: 17 FFSLAASKEAEAARSAPKPMSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVSCNIFINSF 76
Query: 229 ANIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERLWRPDVVLLNAAATTA 405
+I E+ R+ L+ W D RL++N S + +W+PD+ N
Sbjct: 77 GSIAETTMDYRVNIFLRQQWNDPRLAYNEYPDDSLDLDPSMLDSIWKPDLFFANEKGAHF 136
Query: 406 GDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWXNDMXTC 528
+ R+S NG+V + R+ ++ M L N+ D+ TC
Sbjct: 137 HEITTDNKLLRISRNGNVLYSIRITLTLACPMDLKNFPMDVQTC 180
>Z93848-1|CAI41994.1| 376|Homo sapiens glycine receptor, alpha 4
protein.
Length = 376
Score = 36.7 bits (81), Expect = 0.11
Identities = 34/135 (25%), Positives = 56/135 (41%), Gaps = 8/135 (5%)
Frame = +1
Query: 166 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 333
YD P+ K VN+T ++ ++I ++ R+ L+ W D RLS+
Sbjct: 17 YDARIRPNFKGPPVNVTCNIFINSFSSITKTTMDYRVNVFLRQQWNDPRLSYREYPDDSL 76
Query: 334 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLD 501
S + +W+PD+ N + R+ NG+V + RL + M L
Sbjct: 77 DLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLILSCLMDLK 136
Query: 502 NWXNDMXTCTFXFGS 546
N+ D+ TCT S
Sbjct: 137 NFPMDIQTCTMQLES 151
>BC022449-1|AAH22449.1| 474|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, beta 1 protein.
Length = 474
Score = 36.7 bits (81), Expect = 0.11
Identities = 36/165 (21%), Positives = 66/165 (40%), Gaps = 7/165 (4%)
Frame = +1
Query: 103 SAAECENATSLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESESTVRILA 270
S E N + + +D LL YD PD + V + + + + + E +
Sbjct: 27 STNEPSNMSYVKETVDRLLKGYDIRLRPDFGGPPVDVGMRIDVASIDMVSEVNMDYTLTM 86
Query: 271 DLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNN 441
Q +W DKRLS++ + +++L PD LN + ++ R+ +
Sbjct: 87 YFQQSWKDKRLSYSGIPLNLTLDNRVADQLCVPDTYFLNDKKSFVHGVTVKNRMIRLHPD 146
Query: 442 GSVSWIKRLDISTPISMQLDNWXNDMXTCTFXFGSRMHNSDXXDF 576
G+V + R+ + M L + D CT S + +D +F
Sbjct: 147 GTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEF 191
>AL049610-1|CAI42158.1| 376|Homo sapiens glycine receptor, alpha 4
protein.
Length = 376
Score = 36.7 bits (81), Expect = 0.11
Identities = 34/135 (25%), Positives = 56/135 (41%), Gaps = 8/135 (5%)
Frame = +1
Query: 166 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 333
YD P+ K VN+T ++ ++I ++ R+ L+ W D RLS+
Sbjct: 17 YDARIRPNFKGPPVNVTCNIFINSFSSITKTTMDYRVNVFLRQQWNDPRLSYREYPDDSL 76
Query: 334 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLD 501
S + +W+PD+ N + R+ NG+V + RL + M L
Sbjct: 77 DLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLILSCLMDLK 136
Query: 502 NWXNDMXTCTFXFGS 546
N+ D+ TCT S
Sbjct: 137 NFPMDIQTCTMQLES 151
>U93917-1|AAC39917.1| 449|Homo sapiens glycine receptor alpha 3
subunit protein.
Length = 449
Score = 35.9 bits (79), Expect = 0.19
Identities = 32/129 (24%), Positives = 55/129 (42%), Gaps = 8/129 (6%)
Frame = +1
Query: 166 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 333
YD P+ K VN+T ++ +I E+ R+ L+ W D RL+++
Sbjct: 57 YDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPDDSL 116
Query: 334 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLD 501
S + +W+PD+ N + R+ NG+V + RL ++ M L
Sbjct: 117 DLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLK 176
Query: 502 NWXNDMXTC 528
N+ D+ TC
Sbjct: 177 NFPMDVQTC 185
>BC036086-1|AAH36086.1| 464|Homo sapiens glycine receptor, alpha 3
protein.
Length = 464
Score = 35.9 bits (79), Expect = 0.19
Identities = 32/129 (24%), Positives = 55/129 (42%), Gaps = 8/129 (6%)
Frame = +1
Query: 166 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 333
YD P+ K VN+T ++ +I E+ R+ L+ W D RL+++
Sbjct: 57 YDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPDDSL 116
Query: 334 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLD 501
S + +W+PD+ N + R+ NG+V + RL ++ M L
Sbjct: 117 DLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLK 176
Query: 502 NWXNDMXTC 528
N+ D+ TC
Sbjct: 177 NFPMDVQTC 185
>AF017724-1|AAC39919.1| 465|Homo sapiens glycine receptor alpha 3
subunit protein.
Length = 465
Score = 35.9 bits (79), Expect = 0.19
Identities = 32/129 (24%), Positives = 55/129 (42%), Gaps = 8/129 (6%)
Frame = +1
Query: 166 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 333
YD P+ K VN+T ++ +I E+ R+ L+ W D RL+++
Sbjct: 57 YDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPDDSL 116
Query: 334 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLD 501
S + +W+PD+ N + R+ NG+V + RL ++ M L
Sbjct: 117 DLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLK 176
Query: 502 NWXNDMXTC 528
N+ D+ TC
Sbjct: 177 NFPMDVQTC 185
>BC114967-1|AAI14968.1| 366|Homo sapiens GLRA1 protein protein.
Length = 366
Score = 34.7 bits (76), Expect = 0.44
Identities = 24/94 (25%), Positives = 41/94 (43%), Gaps = 4/94 (4%)
Frame = +1
Query: 259 RILADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERLWRPDVVLLNAAATTAGDYALR---A 426
R+ L+ W D RL++N S + +W+PD+ N +
Sbjct: 4 RVNIFLRQQWNDPRLAYNEYPDDSLDLDPSMLDSIWKPDLFFANEKGAHFHEITTDNKLL 63
Query: 427 RVSNNGSVSWIKRLDISTPISMQLDNWXNDMXTC 528
R+S NG+V + R+ ++ M L N+ D+ TC
Sbjct: 64 RISRNGNVLYSIRITLTLACPMDLKNFPMDVQTC 97
>BC146774-1|AAI46775.1| 1114|Homo sapiens GPR124 protein protein.
Length = 1114
Score = 30.7 bits (66), Expect = 7.1
Identities = 16/55 (29%), Positives = 26/55 (47%), Gaps = 1/55 (1%)
Frame = +1
Query: 307 WNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNN-GSVSWIKRL 468
W +GEW C+ + + ++V+L T+ Y RV+NN G W + L
Sbjct: 314 WASGEWECTVSMAQGNASKKVEIVVLE----TSASYCPAERVANNRGDFRWPRTL 364
>AY181242-1|AAO27354.1| 1331|Homo sapiens G protein-coupled receptor
124 protein.
Length = 1331
Score = 30.7 bits (66), Expect = 7.1
Identities = 16/55 (29%), Positives = 26/55 (47%), Gaps = 1/55 (1%)
Frame = +1
Query: 307 WNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNN-GSVSWIKRL 468
W +GEW C+ + + ++V+L T+ Y RV+NN G W + L
Sbjct: 314 WASGEWECTVSMAQGNASKKVEIVVLE----TSASYCPAERVANNRGDFRWPRTL 364
>AK074099-1|BAB84925.1| 1310|Homo sapiens FLJ00170 protein protein.
Length = 1310
Score = 30.7 bits (66), Expect = 7.1
Identities = 16/55 (29%), Positives = 26/55 (47%), Gaps = 1/55 (1%)
Frame = +1
Query: 307 WNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNN-GSVSWIKRL 468
W +GEW C+ + + ++V+L T+ Y RV+NN G W + L
Sbjct: 293 WASGEWECTVSMAQGNASKKVEIVVLE----TSASYCPAERVANNRGDFRWPRTL 343
>AF378755-1|AAL11992.1| 1331|Homo sapiens tumor endothelial marker 5
precursor protein.
Length = 1331
Score = 30.7 bits (66), Expect = 7.1
Identities = 16/55 (29%), Positives = 26/55 (47%), Gaps = 1/55 (1%)
Frame = +1
Query: 307 WNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNN-GSVSWIKRL 468
W +GEW C+ + + ++V+L T+ Y RV+NN G W + L
Sbjct: 314 WASGEWECTVSMAQGNASKKVEIVVLE----TSASYCPAERVANNRGDFRWPRTL 364
>AB040964-1|BAA96055.2| 1206|Homo sapiens KIAA1531 protein protein.
Length = 1206
Score = 30.7 bits (66), Expect = 7.1
Identities = 16/55 (29%), Positives = 26/55 (47%), Gaps = 1/55 (1%)
Frame = +1
Query: 307 WNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNN-GSVSWIKRL 468
W +GEW C+ + + ++V+L T+ Y RV+NN G W + L
Sbjct: 406 WASGEWECTVSMAQGNASKKVEIVVLE----TSASYCPAERVANNRGDFRWPRTL 456
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 106,455,098
Number of Sequences: 237096
Number of extensions: 2247971
Number of successful extensions: 5333
Number of sequences better than 10.0: 162
Number of HSP's better than 10.0 without gapping: 4956
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5212
length of database: 76,859,062
effective HSP length: 89
effective length of database: 55,757,518
effective search space used: 10984231046
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
- SilkBase 1999-2023 -