Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BmNP07_FL5_I05
(907 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
CR542203-1|CAG47000.1| 316|Homo sapiens AKR1B1 protein. 179 1e-44
CR450351-1|CAG29347.1| 316|Homo sapiens AKR1B1 protein. 178 2e-44
J04794-1|AAA51711.1| 325|Homo sapiens ALDR1 protein. 178 3e-44
CR457010-1|CAG33291.1| 325|Homo sapiens AKR1A1 protein. 178 3e-44
BT007003-1|AAP35649.1| 325|Homo sapiens aldo-keto reductase fam... 178 3e-44
BC005394-1|AAH05394.1| 325|Homo sapiens aldo-keto reductase fam... 178 3e-44
BC000670-1|AAH00670.1| 325|Homo sapiens aldo-keto reductase fam... 178 3e-44
AL355480-3|CAI22459.1| 325|Homo sapiens aldo-keto reductase fam... 178 3e-44
AF112485-1|AAF01260.1| 325|Homo sapiens aldehyde reductase prot... 178 3e-44
AF036683-1|AAB92369.1| 325|Homo sapiens aldehyde reductase prot... 178 3e-44
X15414-1|CAA33460.1| 316|Homo sapiens protein ( Human mRNA for ... 177 5e-44
M59783-1|AAA51712.1| 316|Homo sapiens aldose reductase protein. 177 5e-44
M34720-1|AAA35560.1| 316|Homo sapiens protein ( Human aldose re... 177 5e-44
J05474-1|AAA51715.1| 316|Homo sapiens aldose reductase protein. 177 5e-44
J04795-1|AAA51713.1| 316|Homo sapiens ALDR1 protein. 177 5e-44
BT019859-1|AAV38662.1| 316|Homo sapiens aldo-keto reductase fam... 177 5e-44
BC010391-1|AAH10391.1| 316|Homo sapiens aldo-keto reductase fam... 177 5e-44
BC000260-1|AAH00260.1| 316|Homo sapiens aldo-keto reductase fam... 177 5e-44
AF328729-1|AAN09721.1| 316|Homo sapiens CTCL tumor antigen HD-C... 177 5e-44
AF032455-1|AAB88851.1| 316|Homo sapiens aldose reductase protein. 177 5e-44
J05017-1|AAA51714.1| 316|Homo sapiens ALDR1 protein. 176 8e-44
AB209796-1|BAD93033.1| 260|Homo sapiens aldo-keto reductase fam... 176 8e-44
AF149416-1|AAF07272.2| 323|Homo sapiens 3-alpha hydroxysteroid ... 175 1e-43
U05598-1|AAA20937.1| 323|Homo sapiens dihydrodiol dehydrogenase... 174 4e-43
S68330-1|AAD14013.1| 323|Homo sapiens chlordecone reductase hom... 174 4e-43
L32592-1|AAB38486.1| 323|Homo sapiens dihydrodiol dehydrogenase... 174 4e-43
BT006653-1|AAP35299.1| 323|Homo sapiens aldo-keto reductase fam... 174 4e-43
BC063574-1|AAH63574.1| 323|Homo sapiens aldo-keto reductase fam... 174 4e-43
BC007024-1|AAH07024.1| 323|Homo sapiens aldo-keto reductase fam... 174 4e-43
AL713867-1|CAI16408.1| 323|Homo sapiens aldo-keto reductase fam... 174 4e-43
AL391427-1|CAI14726.1| 323|Homo sapiens aldo-keto reductase fam... 174 4e-43
AB209017-1|BAD92254.1| 286|Homo sapiens aldo-keto reductase fam... 174 4e-43
AB032153-1|BAA92891.1| 323|Homo sapiens bile acid-binding prote... 174 4e-43
AB031084-1|BAA92884.1| 323|Homo sapiens bile acid-binding prote... 174 4e-43
AB021654-1|BAA36169.1| 323|Homo sapiens DD2/bile acid-binding p... 174 4e-43
U05861-1|AAA18115.1| 323|Homo sapiens hepatic dihydrodiol dehyd... 173 6e-43
U05684-1|AAA16227.1| 323|Homo sapiens dihydrodiol dehydrogenase... 173 6e-43
M86609-1|AAB02880.1| 323|Homo sapiens dihydrodiol dehydrogenase... 173 6e-43
D17793-1|BAA04619.2| 325|Homo sapiens KIAA0119 protein. 173 6e-43
BT007286-1|AAP35950.1| 323|Homo sapiens aldo-keto reductase fam... 173 6e-43
BT007197-1|AAP35861.1| 323|Homo sapiens aldo-keto reductase fam... 173 6e-43
BC040210-1|AAH40210.1| 323|Homo sapiens aldo-keto reductase fam... 173 6e-43
BC020216-1|AAH20216.1| 323|Homo sapiens aldo-keto reductase fam... 173 6e-43
BC019230-1|AAH19230.1| 323|Homo sapiens aldo-keto reductase fam... 173 6e-43
BC015490-1|AAH15490.1| 323|Homo sapiens aldo-keto reductase fam... 173 6e-43
BC001479-1|AAH01479.1| 323|Homo sapiens aldo-keto reductase fam... 173 6e-43
AL713867-2|CAI16409.1| 323|Homo sapiens aldo-keto reductase fam... 173 6e-43
AL391427-4|CAI14729.1| 323|Homo sapiens aldo-keto reductase fam... 173 6e-43
AB032157-1|BAA92892.1| 323|Homo sapiens prostaglandin F synthas... 173 6e-43
AB032150-1|BAA92886.1| 323|Homo sapiens 20 alph-hydroxysteroid ... 173 6e-43
AB031083-1|BAA92883.1| 323|Homo sapiens 20 alpha-hydroxysteroid... 173 6e-43
AB018580-1|BAA88488.1| 323|Homo sapiens hluPGFS protein. 173 6e-43
DQ269985-1|ABB76132.1| 323|Homo sapiens type II 3a-hydroxystero... 173 7e-43
S68288-1|AAD14011.1| 323|Homo sapiens chlordecone reductase hom... 172 2e-42
BC005387-1|AAH05387.1| 316|Homo sapiens aldo-keto reductase fam... 171 2e-42
L43839-1|AAB41916.1| 323|Homo sapiens 3-alpha-hydroxysteroid de... 171 3e-42
S68290-1|AAD14012.1| 320|Homo sapiens chlordecone reductase hom... 165 1e-40
D26124-1|BAA05121.1| 306|Homo sapiens dihydrodiol dehydrogenase... 164 3e-40
AB045829-1|BAA99542.1| 323|Homo sapiens 3alpha-hydroxysteroid d... 164 3e-40
S68287-1|AAD14010.1| 323|Homo sapiens chlordecone reductase pro... 164 4e-40
D26125-1|BAA05122.1| 321|Homo sapiens 3 alpha-hydroxysteroid/di... 164 4e-40
BC020744-1|AAH20744.1| 323|Homo sapiens aldo-keto reductase fam... 164 4e-40
AL355303-2|CAI14202.1| 323|Homo sapiens aldo-keto reductase fam... 164 4e-40
AB032163-1|BAA92893.1| 323|Homo sapiens dihydrodiol dehydrogena... 164 4e-40
AB031085-1|BAA92885.1| 323|Homo sapiens dihydrodiol dehydrogena... 164 4e-40
U37100-1|AAC17469.1| 316|Homo sapiens aldose reductase-like pep... 158 2e-38
CR541801-1|CAG46600.1| 316|Homo sapiens AKR1B10 protein. 158 2e-38
BT006794-1|AAP35440.1| 316|Homo sapiens aldo-keto reductase fam... 158 2e-38
BC008837-1|AAH08837.1| 316|Homo sapiens aldo-keto reductase fam... 158 2e-38
AF052577-1|AAC36465.1| 316|Homo sapiens aldo-keto reductase pro... 158 2e-38
M33375-1|AAA35658.1| 308|Homo sapiens protein ( Human chlordeco... 158 3e-38
Z28339-1|CAA82193.1| 326|Homo sapiens delta 4-3-oxosteroid 5 be... 156 1e-37
BC130627-1|AAI30628.1| 326|Homo sapiens aldo-keto reductase fam... 156 1e-37
BC130625-1|AAI30626.1| 326|Homo sapiens aldo-keto reductase fam... 156 1e-37
AF283659-1|AAG39381.1| 326|Homo sapiens 5-beta steroid reductas... 156 1e-37
AF524864-1|AAO13380.1| 316|Homo sapiens aldo-ketoreductase prot... 155 2e-37
AL713867-3|CAI16410.1| 247|Homo sapiens aldo-keto reductase fam... 136 8e-32
BC002862-1|AAH02862.1| 307|Homo sapiens AKR1CL2 protein protein. 124 4e-28
AF263242-1|AAK58523.1| 320|Homo sapiens aldo-keto reductase loo... 124 4e-28
AB055603-1|BAC54568.1| 307|Homo sapiens aldo-keto reductase rel... 124 4e-28
AL355480-2|CAI22458.1| 147|Homo sapiens aldo-keto reductase fam... 122 2e-27
AL391427-2|CAI14727.1| 302|Homo sapiens aldo-keto reductase fam... 116 2e-25
AL355303-1|CAI14201.1| 302|Homo sapiens aldo-keto reductase fam... 116 2e-25
AB040822-1|BAC54567.1| 222|Homo sapiens aldo-keto reductase rel... 113 1e-24
AB040821-1|BAC54566.1| 263|Homo sapiens aldo-keto reductase rel... 113 1e-24
AB040820-1|BAC54565.1| 250|Homo sapiens aldo-keto reductase rel... 113 1e-24
AB037902-1|BAA92887.1| 130|Homo sapiens truncated aldo-keto red... 112 2e-24
BC101205-1|AAI01206.1| 129|Homo sapiens aldo-keto reductase fam... 109 2e-23
BC101204-1|AAI01205.1| 129|Homo sapiens aldo-keto reductase fam... 109 2e-23
AK131335-1|BAD18494.1| 129|Homo sapiens protein ( Homo sapiens ... 109 2e-23
AK058142-1|BAB71682.1| 146|Homo sapiens protein ( Homo sapiens ... 58 3e-08
U33429-1|AAC50955.1| 367|Homo sapiens K+ channel beta 2 subunit... 54 5e-07
CR542287-1|CAG47082.1| 353|Homo sapiens KCNAB2 protein. 54 5e-07
BC130413-1|AAI30414.1| 367|Homo sapiens potassium voltage-gated... 54 5e-07
BC126424-1|AAI26425.1| 367|Homo sapiens potassium voltage-gated... 54 5e-07
BC110351-1|AAI10352.1| 395|Homo sapiens KCNAB2 protein protein. 54 5e-07
AL035406-6|CAI19886.1| 253|Homo sapiens potassium voltage-gated... 54 5e-07
AL035406-5|CAI19887.1| 254|Homo sapiens potassium voltage-gated... 54 5e-07
AL035406-4|CAC08512.1| 367|Homo sapiens potassium voltage-gated... 54 5e-07
AL035406-3|CAI19885.1| 353|Homo sapiens potassium voltage-gated... 54 5e-07
AF044253-1|AAB99859.1| 353|Homo sapiens potassium channel beta ... 54 5e-07
AF029749-1|AAB84170.1| 367|Homo sapiens potassium channel beta ... 54 5e-07
X83127-1|CAA58208.1| 401|Homo sapiens voltage gated potassium c... 54 7e-07
U33428-1|AAC50953.1| 401|Homo sapiens K+ channel beta 1a subuni... 54 7e-07
U16953-1|AAC50122.1| 408|Homo sapiens potassium channel beta3 s... 54 7e-07
L47665-1|AAC41926.1| 419|Homo sapiens K+ channel beta-subunit p... 54 7e-07
L39833-1|AAC37573.1| 408|Homo sapiens K+ channel beta-subunit p... 54 7e-07
BC043166-1|AAH43166.1| 401|Homo sapiens potassium voltage-gated... 54 7e-07
AK131252-1|BAD18431.1| 415|Homo sapiens protein ( Homo sapiens ... 54 9e-07
CR542264-1|CAG47060.1| 353|Homo sapiens KCNAB2 protein. 52 2e-06
BC099634-1|AAH99634.1| 404|Homo sapiens potassium voltage-gated... 45 4e-04
BC096234-1|AAH96234.1| 404|Homo sapiens potassium voltage-gated... 45 4e-04
BC096232-1|AAH96232.1| 404|Homo sapiens potassium voltage-gated... 45 4e-04
AF016411-1|AAB92499.1| 404|Homo sapiens KCNA3.1B protein. 44 6e-04
AB028065-1|BAA88489.1| 67|Homo sapiens prostaglandin F synthas... 43 0.002
AB037905-2|BAA92890.1| 45|Homo sapiens truncated aldo-keto red... 40 0.009
AJ278012-1|CAC79668.1| 259|Homo sapiens aflatoxin B1 aldehyde r... 36 0.20
AF026947-1|AAC52104.1| 330|Homo sapiens aflatoxin aldehyde redu... 36 0.27
Y16675-1|CAA76347.1| 330|Homo sapiens aflatoxin B1-aldehyde red... 35 0.35
BT007347-1|AAP36011.1| 330|Homo sapiens aldo-keto reductase fam... 35 0.35
BC013996-1|AAH13996.1| 330|Homo sapiens AKR7A2 protein protein. 35 0.35
BC012171-1|AAH12171.1| 330|Homo sapiens AKR7A2 protein protein. 35 0.35
BC011586-1|AAH11586.1| 330|Homo sapiens AKR7A2 protein protein. 35 0.35
BC010852-1|AAH10852.1| 330|Homo sapiens AKR7A2 protein protein. 35 0.35
BC007352-1|AAH07352.2| 358|Homo sapiens AKR7A2 protein protein. 35 0.35
BC004111-1|AAH04111.3| 330|Homo sapiens AKR7A2 protein protein. 35 0.35
AL035413-8|CAB72321.1| 330|Homo sapiens aldo-keto reductase fam... 35 0.35
BC042420-1|AAH42420.2| 331|Homo sapiens aldo-keto reductase fam... 34 0.62
BC031562-1|AAH31562.1| 331|Homo sapiens aldo-keto reductase fam... 34 0.62
AJ271799-1|CAC81076.1| 331|Homo sapiens aflatoxin B1 aldehyde r... 34 0.62
AF040639-1|AAD02195.1| 331|Homo sapiens aflatoxin B1-aldehyde r... 34 0.62
BC025709-1|AAH25709.1| 331|Homo sapiens aldo-keto reductase fam... 34 0.82
AL035413-11|CAI22232.1| 331|Homo sapiens aldo-keto reductase fa... 34 0.82
>CR542203-1|CAG47000.1| 316|Homo sapiens AKR1B1 protein.
Length = 316
Score = 179 bits (436), Expect = 1e-44
Identities = 96/225 (42%), Positives = 145/225 (64%), Gaps = 13/225 (5%)
Frame = +1
Query: 118 LAPVLKLNNGKEIPGFGIGTWLGTNSNELKGD*VQKSVEWAIDAGYRHIDTAAIYSTEDQ 297
+A L LNNG ++P G+GTW V ++V+ AID GYRHID A +Y E++
Sbjct: 1 MASRLLLNNGAKMPILGLGTWKSPPGQ------VTEAVKVAIDVGYRHIDCAHVYQNENE 54
Query: 298 VGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLIHWPI 477
VG AI++K+ E VVKRE+LF+ +KLW T H+K V A +K+L +L LDY++LYLIHWPI
Sbjct: 55 VGVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPI 114
Query: 478 A---------LHENASI--SQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLEXLKSXG 624
L E+ ++ S T+ ++TW AM +++++GL K+IG+SNFN Q+E + +
Sbjct: 115 GFKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKP 174
Query: 625 GV--TPSVLQVEINLNLQRSALLDYCKAQGIXVVAYTPLRXSVQP 753
G+ P+V Q+E + L + L+ YC+++GI V AY+PL +P
Sbjct: 175 GLKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRP 219
>CR450351-1|CAG29347.1| 316|Homo sapiens AKR1B1 protein.
Length = 316
Score = 178 bits (434), Expect = 2e-44
Identities = 96/225 (42%), Positives = 144/225 (64%), Gaps = 13/225 (5%)
Frame = +1
Query: 118 LAPVLKLNNGKEIPGFGIGTWLGTNSNELKGD*VQKSVEWAIDAGYRHIDTAAIYSTEDQ 297
+A L LNNG ++P G+GTW V ++V+ AID GYRHID A +Y E++
Sbjct: 1 MASRLLLNNGAKMPILGLGTWKSPPGQ------VTEAVKVAIDVGYRHIDCAHVYQNENE 54
Query: 298 VGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLIHWP- 474
VG AI++K+ E VVKRE+LF+ +KLW T H+K V A +K+L +L LDY++LYLIHWP
Sbjct: 55 VGVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPT 114
Query: 475 --------IALHENASI--SQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLEXLKSXG 624
L E+ ++ S T+ ++TW AM +++++GL K+IG+SNFN Q+E + S
Sbjct: 115 GFRPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILSKP 174
Query: 625 GV--TPSVLQVEINLNLQRSALLDYCKAQGIXVVAYTPLRXSVQP 753
G+ P+V Q+E + L + L+ YC+++GI V AY+PL +P
Sbjct: 175 GLKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRP 219
>J04794-1|AAA51711.1| 325|Homo sapiens ALDR1 protein.
Length = 325
Score = 178 bits (433), Expect = 3e-44
Identities = 92/220 (41%), Positives = 140/220 (63%), Gaps = 12/220 (5%)
Frame = +1
Query: 121 APVLKLNNGKEIPGFGIGTWLGTNSNELKGD*VQKSVEWAIDAGYRHIDTAAIYSTEDQV 300
A + L+ G+++P G+GTW V+ +V++A+ GYRHID AAIY E ++
Sbjct: 3 ASCVLLHTGQKMPLIGLGTWKSEPGQ------VKAAVKYALSVGYRHIDCAAIYGNEPEI 56
Query: 301 GRAIKKKIAEG-VVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLIHWPI 477
G A+K+ + G V RE+LFVT+KLWNT H E V PALRK+L +L L+Y++LYL+HWP
Sbjct: 57 GEALKEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPY 116
Query: 478 ALH-------ENAS----ISQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLEXLKSXG 624
A +NA T Y ETW+A+ ++ +GL +++G+SNFN +Q++ + S
Sbjct: 117 AFERGDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVA 176
Query: 625 GVTPSVLQVEINLNLQRSALLDYCKAQGIXVVAYTPLRXS 744
V P+VLQVE + L ++ L+ +C+A+G+ V AY+PL S
Sbjct: 177 SVRPAVLQVECHPYLAQNELIAHCQARGLEVTAYSPLGSS 216
>CR457010-1|CAG33291.1| 325|Homo sapiens AKR1A1 protein.
Length = 325
Score = 178 bits (433), Expect = 3e-44
Identities = 92/220 (41%), Positives = 140/220 (63%), Gaps = 12/220 (5%)
Frame = +1
Query: 121 APVLKLNNGKEIPGFGIGTWLGTNSNELKGD*VQKSVEWAIDAGYRHIDTAAIYSTEDQV 300
A + L+ G+++P G+GTW V+ +V++A+ GYRHID AAIY E ++
Sbjct: 3 ASCVLLHTGQKMPLIGLGTWKSEPGQ------VKAAVKYALSVGYRHIDCAAIYGNEPEI 56
Query: 301 GRAIKKKIAEG-VVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLIHWPI 477
G A+K+ + G V RE+LFVT+KLWNT H E V PALRK+L +L L+Y++LYL+HWP
Sbjct: 57 GEALKEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPY 116
Query: 478 ALH-------ENAS----ISQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLEXLKSXG 624
A +NA T Y ETW+A+ ++ +GL +++G+SNFN +Q++ + S
Sbjct: 117 AFERGDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVA 176
Query: 625 GVTPSVLQVEINLNLQRSALLDYCKAQGIXVVAYTPLRXS 744
V P+VLQVE + L ++ L+ +C+A+G+ V AY+PL S
Sbjct: 177 SVRPAVLQVECHPYLAQNELIAHCQARGLEVTAYSPLGSS 216
>BT007003-1|AAP35649.1| 325|Homo sapiens aldo-keto reductase family
1, member A1 (aldehyde reductase) protein.
Length = 325
Score = 178 bits (433), Expect = 3e-44
Identities = 92/220 (41%), Positives = 140/220 (63%), Gaps = 12/220 (5%)
Frame = +1
Query: 121 APVLKLNNGKEIPGFGIGTWLGTNSNELKGD*VQKSVEWAIDAGYRHIDTAAIYSTEDQV 300
A + L+ G+++P G+GTW V+ +V++A+ GYRHID AAIY E ++
Sbjct: 3 ASCVLLHTGQKMPLIGLGTWKSEPGQ------VKAAVKYALSVGYRHIDCAAIYGNEPEI 56
Query: 301 GRAIKKKIAEG-VVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLIHWPI 477
G A+K+ + G V RE+LFVT+KLWNT H E V PALRK+L +L L+Y++LYL+HWP
Sbjct: 57 GEALKEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPY 116
Query: 478 ALH-------ENAS----ISQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLEXLKSXG 624
A +NA T Y ETW+A+ ++ +GL +++G+SNFN +Q++ + S
Sbjct: 117 AFERGDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVA 176
Query: 625 GVTPSVLQVEINLNLQRSALLDYCKAQGIXVVAYTPLRXS 744
V P+VLQVE + L ++ L+ +C+A+G+ V AY+PL S
Sbjct: 177 SVRPAVLQVECHPYLAQNELIAHCQARGLEVTAYSPLGSS 216
>BC005394-1|AAH05394.1| 325|Homo sapiens aldo-keto reductase family
1, member A1 (aldehyde reductase) protein.
Length = 325
Score = 178 bits (433), Expect = 3e-44
Identities = 92/220 (41%), Positives = 140/220 (63%), Gaps = 12/220 (5%)
Frame = +1
Query: 121 APVLKLNNGKEIPGFGIGTWLGTNSNELKGD*VQKSVEWAIDAGYRHIDTAAIYSTEDQV 300
A + L+ G+++P G+GTW V+ +V++A+ GYRHID AAIY E ++
Sbjct: 3 ASCVLLHTGQKMPLIGLGTWKSEPGQ------VKAAVKYALSVGYRHIDCAAIYGNEPEI 56
Query: 301 GRAIKKKIAEG-VVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLIHWPI 477
G A+K+ + G V RE+LFVT+KLWNT H E V PALRK+L +L L+Y++LYL+HWP
Sbjct: 57 GEALKEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPY 116
Query: 478 ALH-------ENAS----ISQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLEXLKSXG 624
A +NA T Y ETW+A+ ++ +GL +++G+SNFN +Q++ + S
Sbjct: 117 AFERGDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVA 176
Query: 625 GVTPSVLQVEINLNLQRSALLDYCKAQGIXVVAYTPLRXS 744
V P+VLQVE + L ++ L+ +C+A+G+ V AY+PL S
Sbjct: 177 SVRPAVLQVECHPYLAQNELIAHCQARGLEVTAYSPLGSS 216
>BC000670-1|AAH00670.1| 325|Homo sapiens aldo-keto reductase family
1, member A1 (aldehyde reductase) protein.
Length = 325
Score = 178 bits (433), Expect = 3e-44
Identities = 92/220 (41%), Positives = 140/220 (63%), Gaps = 12/220 (5%)
Frame = +1
Query: 121 APVLKLNNGKEIPGFGIGTWLGTNSNELKGD*VQKSVEWAIDAGYRHIDTAAIYSTEDQV 300
A + L+ G+++P G+GTW V+ +V++A+ GYRHID AAIY E ++
Sbjct: 3 ASCVLLHTGQKMPLIGLGTWKSEPGQ------VKAAVKYALSVGYRHIDCAAIYGNEPEI 56
Query: 301 GRAIKKKIAEG-VVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLIHWPI 477
G A+K+ + G V RE+LFVT+KLWNT H E V PALRK+L +L L+Y++LYL+HWP
Sbjct: 57 GEALKEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPY 116
Query: 478 ALH-------ENAS----ISQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLEXLKSXG 624
A +NA T Y ETW+A+ ++ +GL +++G+SNFN +Q++ + S
Sbjct: 117 AFERGDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVA 176
Query: 625 GVTPSVLQVEINLNLQRSALLDYCKAQGIXVVAYTPLRXS 744
V P+VLQVE + L ++ L+ +C+A+G+ V AY+PL S
Sbjct: 177 SVRPAVLQVECHPYLAQNELIAHCQARGLEVTAYSPLGSS 216
>AL355480-3|CAI22459.1| 325|Homo sapiens aldo-keto reductase family
1, member A1 (aldehydetase, 1 protein.
Length = 325
Score = 178 bits (433), Expect = 3e-44
Identities = 92/220 (41%), Positives = 140/220 (63%), Gaps = 12/220 (5%)
Frame = +1
Query: 121 APVLKLNNGKEIPGFGIGTWLGTNSNELKGD*VQKSVEWAIDAGYRHIDTAAIYSTEDQV 300
A + L+ G+++P G+GTW V+ +V++A+ GYRHID AAIY E ++
Sbjct: 3 ASCVLLHTGQKMPLIGLGTWKSEPGQ------VKAAVKYALSVGYRHIDCAAIYGNEPEI 56
Query: 301 GRAIKKKIAEG-VVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLIHWPI 477
G A+K+ + G V RE+LFVT+KLWNT H E V PALRK+L +L L+Y++LYL+HWP
Sbjct: 57 GEALKEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPY 116
Query: 478 ALH-------ENAS----ISQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLEXLKSXG 624
A +NA T Y ETW+A+ ++ +GL +++G+SNFN +Q++ + S
Sbjct: 117 AFERGDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVA 176
Query: 625 GVTPSVLQVEINLNLQRSALLDYCKAQGIXVVAYTPLRXS 744
V P+VLQVE + L ++ L+ +C+A+G+ V AY+PL S
Sbjct: 177 SVRPAVLQVECHPYLAQNELIAHCQARGLEVTAYSPLGSS 216
>AF112485-1|AAF01260.1| 325|Homo sapiens aldehyde reductase
protein.
Length = 325
Score = 178 bits (433), Expect = 3e-44
Identities = 92/220 (41%), Positives = 140/220 (63%), Gaps = 12/220 (5%)
Frame = +1
Query: 121 APVLKLNNGKEIPGFGIGTWLGTNSNELKGD*VQKSVEWAIDAGYRHIDTAAIYSTEDQV 300
A + L+ G+++P G+GTW V+ +V++A+ GYRHID AAIY E ++
Sbjct: 3 ASCVLLHTGQKMPLIGLGTWKSEPGQ------VKAAVKYALSVGYRHIDCAAIYGNEPEI 56
Query: 301 GRAIKKKIAEG-VVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLIHWPI 477
G A+K+ + G V RE+LFVT+KLWNT H E V PALRK+L +L L+Y++LYL+HWP
Sbjct: 57 GEALKEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPY 116
Query: 478 ALH-------ENAS----ISQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLEXLKSXG 624
A +NA T Y ETW+A+ ++ +GL +++G+SNFN +Q++ + S
Sbjct: 117 AFERGDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVA 176
Query: 625 GVTPSVLQVEINLNLQRSALLDYCKAQGIXVVAYTPLRXS 744
V P+VLQVE + L ++ L+ +C+A+G+ V AY+PL S
Sbjct: 177 SVRPAVLQVECHPYLAQNELIAHCQARGLEVTAYSPLGSS 216
>AF036683-1|AAB92369.1| 325|Homo sapiens aldehyde reductase
protein.
Length = 325
Score = 178 bits (433), Expect = 3e-44
Identities = 92/220 (41%), Positives = 140/220 (63%), Gaps = 12/220 (5%)
Frame = +1
Query: 121 APVLKLNNGKEIPGFGIGTWLGTNSNELKGD*VQKSVEWAIDAGYRHIDTAAIYSTEDQV 300
A + L+ G+++P G+GTW V+ +V++A+ GYRHID AAIY E ++
Sbjct: 3 ASCVLLHTGQKMPLIGLGTWKSEPGQ------VKAAVKYALSVGYRHIDCAAIYGNEPEI 56
Query: 301 GRAIKKKIAEG-VVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLIHWPI 477
G A+K+ + G V RE+LFVT+KLWNT H E V PALRK+L +L L+Y++LYL+HWP
Sbjct: 57 GEALKEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPY 116
Query: 478 ALH-------ENAS----ISQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLEXLKSXG 624
A +NA T Y ETW+A+ ++ +GL +++G+SNFN +Q++ + S
Sbjct: 117 AFERGDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVA 176
Query: 625 GVTPSVLQVEINLNLQRSALLDYCKAQGIXVVAYTPLRXS 744
V P+VLQVE + L ++ L+ +C+A+G+ V AY+PL S
Sbjct: 177 SVRPAVLQVECHPYLAQNELIAHCQARGLEVTAYSPLGSS 216
>X15414-1|CAA33460.1| 316|Homo sapiens protein ( Human mRNA for
aldose reductase (EC 1.1.1.2). ).
Length = 316
Score = 177 bits (431), Expect = 5e-44
Identities = 95/225 (42%), Positives = 144/225 (64%), Gaps = 13/225 (5%)
Frame = +1
Query: 118 LAPVLKLNNGKEIPGFGIGTWLGTNSNELKGD*VQKSVEWAIDAGYRHIDTAAIYSTEDQ 297
+A L LNNG ++P G+GTW V ++V+ AID GYRHID A +Y E++
Sbjct: 1 MASRLLLNNGAKMPILGLGTWKSPPGQ------VTEAVKVAIDVGYRHIDCAHVYQNENE 54
Query: 298 VGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLIHWP- 474
VG AI++K+ E VVKRE+LF+ +KLW T H+K V A +K+L +L LDY++LYLIHWP
Sbjct: 55 VGVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPT 114
Query: 475 --------IALHENASI--SQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLEXLKSXG 624
L E+ ++ S T+ ++TW AM +++++GL K+IG+SNFN Q+E + +
Sbjct: 115 GFKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKP 174
Query: 625 GV--TPSVLQVEINLNLQRSALLDYCKAQGIXVVAYTPLRXSVQP 753
G+ P+V Q+E + L + L+ YC+++GI V AY+PL +P
Sbjct: 175 GLKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRP 219
>M59783-1|AAA51712.1| 316|Homo sapiens aldose reductase protein.
Length = 316
Score = 177 bits (431), Expect = 5e-44
Identities = 95/225 (42%), Positives = 144/225 (64%), Gaps = 13/225 (5%)
Frame = +1
Query: 118 LAPVLKLNNGKEIPGFGIGTWLGTNSNELKGD*VQKSVEWAIDAGYRHIDTAAIYSTEDQ 297
+A L LNNG ++P G+GTW V ++V+ AID GYRHID A +Y E++
Sbjct: 1 MASRLLLNNGAKMPILGLGTWKSPPGQ------VTEAVKVAIDVGYRHIDCAHVYQNENE 54
Query: 298 VGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLIHWP- 474
VG AI++K+ E VVKRE+LF+ +KLW T H+K V A +K+L +L LDY++LYLIHWP
Sbjct: 55 VGVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPT 114
Query: 475 --------IALHENASI--SQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLEXLKSXG 624
L E+ ++ S T+ ++TW AM +++++GL K+IG+SNFN Q+E + +
Sbjct: 115 GFKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKP 174
Query: 625 GV--TPSVLQVEINLNLQRSALLDYCKAQGIXVVAYTPLRXSVQP 753
G+ P+V Q+E + L + L+ YC+++GI V AY+PL +P
Sbjct: 175 GLKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRP 219
>M34720-1|AAA35560.1| 316|Homo sapiens protein ( Human aldose
reductase mRNA, complete cds. ).
Length = 316
Score = 177 bits (431), Expect = 5e-44
Identities = 95/225 (42%), Positives = 144/225 (64%), Gaps = 13/225 (5%)
Frame = +1
Query: 118 LAPVLKLNNGKEIPGFGIGTWLGTNSNELKGD*VQKSVEWAIDAGYRHIDTAAIYSTEDQ 297
+A L LNNG ++P G+GTW V ++V+ AID GYRHID A +Y E++
Sbjct: 1 MASRLLLNNGAKMPILGLGTWKSPPGQ------VTEAVKVAIDVGYRHIDCAHVYQNENE 54
Query: 298 VGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLIHWP- 474
VG AI++K+ E VVKRE+LF+ +KLW T H+K V A +K+L +L LDY++LYLIHWP
Sbjct: 55 VGVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPT 114
Query: 475 --------IALHENASI--SQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLEXLKSXG 624
L E+ ++ S T+ ++TW AM +++++GL K+IG+SNFN Q+E + +
Sbjct: 115 GFKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKP 174
Query: 625 GV--TPSVLQVEINLNLQRSALLDYCKAQGIXVVAYTPLRXSVQP 753
G+ P+V Q+E + L + L+ YC+++GI V AY+PL +P
Sbjct: 175 GLKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRP 219
>J05474-1|AAA51715.1| 316|Homo sapiens aldose reductase protein.
Length = 316
Score = 177 bits (431), Expect = 5e-44
Identities = 95/225 (42%), Positives = 144/225 (64%), Gaps = 13/225 (5%)
Frame = +1
Query: 118 LAPVLKLNNGKEIPGFGIGTWLGTNSNELKGD*VQKSVEWAIDAGYRHIDTAAIYSTEDQ 297
+A L LNNG ++P G+GTW V ++V+ AID GYRHID A +Y E++
Sbjct: 1 MASRLLLNNGAKMPILGLGTWKSPPGQ------VTEAVKVAIDVGYRHIDCAHVYQNENE 54
Query: 298 VGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLIHWP- 474
VG AI++K+ E VVKRE+LF+ +KLW T H+K V A +K+L +L LDY++LYLIHWP
Sbjct: 55 VGVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPT 114
Query: 475 --------IALHENASI--SQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLEXLKSXG 624
L E+ ++ S T+ ++TW AM +++++GL K+IG+SNFN Q+E + +
Sbjct: 115 GFKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKP 174
Query: 625 GV--TPSVLQVEINLNLQRSALLDYCKAQGIXVVAYTPLRXSVQP 753
G+ P+V Q+E + L + L+ YC+++GI V AY+PL +P
Sbjct: 175 GLKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRP 219
>J04795-1|AAA51713.1| 316|Homo sapiens ALDR1 protein.
Length = 316
Score = 177 bits (431), Expect = 5e-44
Identities = 95/225 (42%), Positives = 144/225 (64%), Gaps = 13/225 (5%)
Frame = +1
Query: 118 LAPVLKLNNGKEIPGFGIGTWLGTNSNELKGD*VQKSVEWAIDAGYRHIDTAAIYSTEDQ 297
+A L LNNG ++P G+GTW V ++V+ AID GYRHID A +Y E++
Sbjct: 1 MASRLLLNNGAKMPILGLGTWKSPPGQ------VTEAVKVAIDVGYRHIDCAHVYQNENE 54
Query: 298 VGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLIHWP- 474
VG AI++K+ E VVKRE+LF+ +KLW T H+K V A +K+L +L LDY++LYLIHWP
Sbjct: 55 VGVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPT 114
Query: 475 --------IALHENASI--SQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLEXLKSXG 624
L E+ ++ S T+ ++TW AM +++++GL K+IG+SNFN Q+E + +
Sbjct: 115 GFKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKP 174
Query: 625 GV--TPSVLQVEINLNLQRSALLDYCKAQGIXVVAYTPLRXSVQP 753
G+ P+V Q+E + L + L+ YC+++GI V AY+PL +P
Sbjct: 175 GLKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRP 219
>BT019859-1|AAV38662.1| 316|Homo sapiens aldo-keto reductase family
1, member B1 (aldose reductase) protein.
Length = 316
Score = 177 bits (431), Expect = 5e-44
Identities = 95/225 (42%), Positives = 144/225 (64%), Gaps = 13/225 (5%)
Frame = +1
Query: 118 LAPVLKLNNGKEIPGFGIGTWLGTNSNELKGD*VQKSVEWAIDAGYRHIDTAAIYSTEDQ 297
+A L LNNG ++P G+GTW V ++V+ AID GYRHID A +Y E++
Sbjct: 1 MASRLLLNNGAKMPILGLGTWKSPPGQ------VTEAVKVAIDVGYRHIDCAHVYQNENE 54
Query: 298 VGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLIHWP- 474
VG AI++K+ E VVKRE+LF+ +KLW T H+K V A +K+L +L LDY++LYLIHWP
Sbjct: 55 VGVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPT 114
Query: 475 --------IALHENASI--SQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLEXLKSXG 624
L E+ ++ S T+ ++TW AM +++++GL K+IG+SNFN Q+E + +
Sbjct: 115 GFKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKP 174
Query: 625 GV--TPSVLQVEINLNLQRSALLDYCKAQGIXVVAYTPLRXSVQP 753
G+ P+V Q+E + L + L+ YC+++GI V AY+PL +P
Sbjct: 175 GLKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRP 219
>BC010391-1|AAH10391.1| 316|Homo sapiens aldo-keto reductase family
1, member B1 (aldose reductase) protein.
Length = 316
Score = 177 bits (431), Expect = 5e-44
Identities = 95/225 (42%), Positives = 144/225 (64%), Gaps = 13/225 (5%)
Frame = +1
Query: 118 LAPVLKLNNGKEIPGFGIGTWLGTNSNELKGD*VQKSVEWAIDAGYRHIDTAAIYSTEDQ 297
+A L LNNG ++P G+GTW V ++V+ AID GYRHID A +Y E++
Sbjct: 1 MASRLLLNNGAKMPILGLGTWKSPPGQ------VTEAVKVAIDVGYRHIDCAHVYQNENE 54
Query: 298 VGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLIHWP- 474
VG AI++K+ E VVKRE+LF+ +KLW T H+K V A +K+L +L LDY++LYLIHWP
Sbjct: 55 VGVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPT 114
Query: 475 --------IALHENASI--SQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLEXLKSXG 624
L E+ ++ S T+ ++TW AM +++++GL K+IG+SNFN Q+E + +
Sbjct: 115 GFKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKP 174
Query: 625 GV--TPSVLQVEINLNLQRSALLDYCKAQGIXVVAYTPLRXSVQP 753
G+ P+V Q+E + L + L+ YC+++GI V AY+PL +P
Sbjct: 175 GLKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRP 219
>BC000260-1|AAH00260.1| 316|Homo sapiens aldo-keto reductase family
1, member B1 (aldose reductase) protein.
Length = 316
Score = 177 bits (431), Expect = 5e-44
Identities = 95/225 (42%), Positives = 144/225 (64%), Gaps = 13/225 (5%)
Frame = +1
Query: 118 LAPVLKLNNGKEIPGFGIGTWLGTNSNELKGD*VQKSVEWAIDAGYRHIDTAAIYSTEDQ 297
+A L LNNG ++P G+GTW V ++V+ AID GYRHID A +Y E++
Sbjct: 1 MASRLLLNNGAKMPILGLGTWKSPPGQ------VTEAVKVAIDVGYRHIDCAHVYQNENE 54
Query: 298 VGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLIHWP- 474
VG AI++K+ E VVKRE+LF+ +KLW T H+K V A +K+L +L LDY++LYLIHWP
Sbjct: 55 VGVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPT 114
Query: 475 --------IALHENASI--SQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLEXLKSXG 624
L E+ ++ S T+ ++TW AM +++++GL K+IG+SNFN Q+E + +
Sbjct: 115 GFKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKP 174
Query: 625 GV--TPSVLQVEINLNLQRSALLDYCKAQGIXVVAYTPLRXSVQP 753
G+ P+V Q+E + L + L+ YC+++GI V AY+PL +P
Sbjct: 175 GLKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRP 219
>AF328729-1|AAN09721.1| 316|Homo sapiens CTCL tumor antigen
HD-CL-07 protein.
Length = 316
Score = 177 bits (431), Expect = 5e-44
Identities = 95/225 (42%), Positives = 144/225 (64%), Gaps = 13/225 (5%)
Frame = +1
Query: 118 LAPVLKLNNGKEIPGFGIGTWLGTNSNELKGD*VQKSVEWAIDAGYRHIDTAAIYSTEDQ 297
+A L LNNG ++P G+GTW V ++V+ AID GYRHID A +Y E++
Sbjct: 1 MASRLLLNNGAKMPILGLGTWKSPPGQ------VTEAVKVAIDVGYRHIDCAHVYQNENE 54
Query: 298 VGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLIHWP- 474
VG AI++K+ E VVKRE+LF+ +KLW T H+K V A +K+L +L LDY++LYLIHWP
Sbjct: 55 VGVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPT 114
Query: 475 --------IALHENASI--SQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLEXLKSXG 624
L E+ ++ S T+ ++TW AM +++++GL K+IG+SNFN Q+E + +
Sbjct: 115 GFKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKP 174
Query: 625 GV--TPSVLQVEINLNLQRSALLDYCKAQGIXVVAYTPLRXSVQP 753
G+ P+V Q+E + L + L+ YC+++GI V AY+PL +P
Sbjct: 175 GLKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRP 219
>AF032455-1|AAB88851.1| 316|Homo sapiens aldose reductase protein.
Length = 316
Score = 177 bits (431), Expect = 5e-44
Identities = 95/225 (42%), Positives = 144/225 (64%), Gaps = 13/225 (5%)
Frame = +1
Query: 118 LAPVLKLNNGKEIPGFGIGTWLGTNSNELKGD*VQKSVEWAIDAGYRHIDTAAIYSTEDQ 297
+A L LNNG ++P G+GTW V ++V+ AID GYRHID A +Y E++
Sbjct: 1 MASRLLLNNGAKMPILGLGTWKSPPGQ------VTEAVKVAIDVGYRHIDCAHVYQNENE 54
Query: 298 VGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLIHWP- 474
VG AI++K+ E VVKRE+LF+ +KLW T H+K V A +K+L +L LDY++LYLIHWP
Sbjct: 55 VGVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPT 114
Query: 475 --------IALHENASI--SQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLEXLKSXG 624
L E+ ++ S T+ ++TW AM +++++GL K+IG+SNFN Q+E + +
Sbjct: 115 GFKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKP 174
Query: 625 GV--TPSVLQVEINLNLQRSALLDYCKAQGIXVVAYTPLRXSVQP 753
G+ P+V Q+E + L + L+ YC+++GI V AY+PL +P
Sbjct: 175 GLKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRP 219
>J05017-1|AAA51714.1| 316|Homo sapiens ALDR1 protein.
Length = 316
Score = 176 bits (429), Expect = 8e-44
Identities = 94/225 (41%), Positives = 144/225 (64%), Gaps = 13/225 (5%)
Frame = +1
Query: 118 LAPVLKLNNGKEIPGFGIGTWLGTNSNELKGD*VQKSVEWAIDAGYRHIDTAAIYSTEDQ 297
+A + LNNG ++P G+GTW V ++V+ AID GYRHID A +Y E++
Sbjct: 1 MASRILLNNGAKMPILGLGTWKSPPGQ------VTEAVKVAIDVGYRHIDCAHVYQNENE 54
Query: 298 VGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLIHWP- 474
VG AI++K+ E VVKRE+LF+ +KLW T H+K V A +K+L +L LDY++LYLIHWP
Sbjct: 55 VGVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPT 114
Query: 475 --------IALHENASI--SQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLEXLKSXG 624
L E+ ++ S T+ ++TW AM +++++GL K+IG+SNFN Q+E + +
Sbjct: 115 GFKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKP 174
Query: 625 GV--TPSVLQVEINLNLQRSALLDYCKAQGIXVVAYTPLRXSVQP 753
G+ P+V Q+E + L + L+ YC+++GI V AY+PL +P
Sbjct: 175 GLKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRP 219
>AB209796-1|BAD93033.1| 260|Homo sapiens aldo-keto reductase family
1, member B1 variant protein.
Length = 260
Score = 176 bits (429), Expect = 8e-44
Identities = 94/221 (42%), Positives = 142/221 (64%), Gaps = 13/221 (5%)
Frame = +1
Query: 130 LKLNNGKEIPGFGIGTWLGTNSNELKGD*VQKSVEWAIDAGYRHIDTAAIYSTEDQVGRA 309
L LNNG ++P G+GTW V ++V+ AID GYRHID A +Y E++VG A
Sbjct: 2 LLLNNGAKMPILGLGTWKSPPGQ------VTEAVKVAIDVGYRHIDCAHVYQNENEVGVA 55
Query: 310 IKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLIHWP----- 474
I++K+ E VVKRE+LF+ +KLW T H+K V A +K+L +L LDY++LYLIHWP
Sbjct: 56 IQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKP 115
Query: 475 ----IALHENASI--SQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLEXLKSXGGV-- 630
L E+ ++ S T+ ++TW AM +++++GL K+IG+SNFN Q+E + + G+
Sbjct: 116 GKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKY 175
Query: 631 TPSVLQVEINLNLQRSALLDYCKAQGIXVVAYTPLRXSVQP 753
P+V Q+E + L + L+ YC+++GI V AY+PL +P
Sbjct: 176 KPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRP 216
>AF149416-1|AAF07272.2| 323|Homo sapiens 3-alpha hydroxysteroid
dehydrogenase type IIb protein.
Length = 323
Score = 175 bits (427), Expect = 1e-43
Identities = 100/215 (46%), Positives = 133/215 (61%), Gaps = 13/215 (6%)
Frame = +1
Query: 130 LKLNNGKEIPGFGIGTWLGTNSNELKGD*VQKSVEWAIDAGYRHIDTAAIYSTEDQVGRA 309
+KLN+G +P G GT+ K V K AI+AG+RHID+A +Y+ E+QVG A
Sbjct: 8 VKLNDGHFMPVLGFGTYAPPEVPRSKALEVSKL---AIEAGFRHIDSAHLYNNEEQVGLA 64
Query: 310 IKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLIHWPIALHE 489
I+ KIA+G VKRED+F T+KLW+T+H+ E V PAL SLK LDYV+LYLIH P++L
Sbjct: 65 IRSKIADGSVKREDIFYTSKLWSTSHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLKP 124
Query: 490 NASISQT-----------DYVETWQAMTDVLNQGLTKSIGVSNFNIQQLEXLKSXGGV-- 630
+S T D TW+AM + GL KSIGVSNFN +QLE + + G+
Sbjct: 125 GEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKY 184
Query: 631 TPSVLQVEINLNLQRSALLDYCKAQGIXVVAYTPL 735
P QVE + RS LLD+CK++ I +VAY+ L
Sbjct: 185 KPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSAL 219
>U05598-1|AAA20937.1| 323|Homo sapiens dihydrodiol dehydrogenase
protein.
Length = 323
Score = 174 bits (423), Expect = 4e-43
Identities = 98/224 (43%), Positives = 139/224 (62%), Gaps = 13/224 (5%)
Frame = +1
Query: 130 LKLNNGKEIPGFGIGTWLGTNSNELKGD*VQKSVEWAIDAGYRHIDTAAIYSTEDQVGRA 309
+KLN+G +P G GT+ + K ++V+ AI+AG+ HID+A +Y+ E+QVG A
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKA---LEAVKLAIEAGFHHIDSAHVYNNEEQVGLA 64
Query: 310 IKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLIHWPIAL-- 483
I+ KIA+G VKRED+F T+KLW+ +H+ E V PAL +SLKNL LDYV+LYLIH+P+++
Sbjct: 65 IRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKP 124
Query: 484 -------HENASI--SQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLEXLKSXGGV-- 630
EN I D TW+AM + GL KSIGVSNFN + LE + + G+
Sbjct: 125 GEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKY 184
Query: 631 TPSVLQVEINLNLQRSALLDYCKAQGIXVVAYTPLRXSVQPPAV 762
P QVE + + LLD+CK++ I +VAY+ L + P V
Sbjct: 185 KPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWV 228
>S68330-1|AAD14013.1| 323|Homo sapiens chlordecone reductase
homolog protein.
Length = 323
Score = 174 bits (423), Expect = 4e-43
Identities = 98/224 (43%), Positives = 139/224 (62%), Gaps = 13/224 (5%)
Frame = +1
Query: 130 LKLNNGKEIPGFGIGTWLGTNSNELKGD*VQKSVEWAIDAGYRHIDTAAIYSTEDQVGRA 309
+KLN+G +P G GT+ + K ++V+ AI+AG+ HID+A +Y+ E+QVG A
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKA---LEAVKLAIEAGFHHIDSAHVYNNEEQVGLA 64
Query: 310 IKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLIHWPIAL-- 483
I+ KIA+G VKRED+F T+KLW+ +H+ E V PAL +SLKNL LDYV+LYLIH+P+++
Sbjct: 65 IRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKP 124
Query: 484 -------HENASI--SQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLEXLKSXGGV-- 630
EN I D TW+AM + GL KSIGVSNFN + LE + + G+
Sbjct: 125 GEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNEPGLKY 184
Query: 631 TPSVLQVEINLNLQRSALLDYCKAQGIXVVAYTPLRXSVQPPAV 762
P QVE + + LLD+CK++ I +VAY+ L + P V
Sbjct: 185 EPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWV 228
>L32592-1|AAB38486.1| 323|Homo sapiens dihydrodiol
dehydrogenase/bile acid-binding protein protein.
Length = 323
Score = 174 bits (423), Expect = 4e-43
Identities = 98/224 (43%), Positives = 138/224 (61%), Gaps = 13/224 (5%)
Frame = +1
Query: 130 LKLNNGKEIPGFGIGTWLGTNSNELKGD*VQKSVEWAIDAGYRHIDTAAIYSTEDQVGRA 309
+KLN+G +P G GT+ + K ++V+ AI+AGY HID+A +Y+ E+QVG A
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKA---LEAVKLAIEAGYHHIDSAHVYNNEEQVGLA 64
Query: 310 IKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLIHWPIAL-- 483
I+ KIA+G VKRED+F T+KLW+ +H+ E V PAL +SLKNL LDY +LYLIH+P+++
Sbjct: 65 IRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYADLYLIHFPVSVKP 124
Query: 484 -------HENASI--SQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLEXLKSXGGV-- 630
EN I D TW+AM + GL KSIGVSNFN + LE + + G+
Sbjct: 125 GEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNEPGLKY 184
Query: 631 TPSVLQVEINLNLQRSALLDYCKAQGIXVVAYTPLRXSVQPPAV 762
P QVE + + LLD+CK++ I +VAY+ L + P V
Sbjct: 185 EPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWV 228
>BT006653-1|AAP35299.1| 323|Homo sapiens aldo-keto reductase family
1, member C2 (dihydrodiol dehydrogenase 2; bile acid
protein.
Length = 323
Score = 174 bits (423), Expect = 4e-43
Identities = 98/224 (43%), Positives = 139/224 (62%), Gaps = 13/224 (5%)
Frame = +1
Query: 130 LKLNNGKEIPGFGIGTWLGTNSNELKGD*VQKSVEWAIDAGYRHIDTAAIYSTEDQVGRA 309
+KLN+G +P G GT+ + K ++V+ AI+AG+ HID+A +Y+ E+QVG A
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKA---LEAVKLAIEAGFHHIDSAHVYNNEEQVGLA 64
Query: 310 IKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLIHWPIAL-- 483
I+ KIA+G VKRED+F T+KLW+ +H+ E V PAL +SLKNL LDYV+LYLIH+P+++
Sbjct: 65 IRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKP 124
Query: 484 -------HENASI--SQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLEXLKSXGGV-- 630
EN I D TW+AM + GL KSIGVSNFN + LE + + G+
Sbjct: 125 GEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKY 184
Query: 631 TPSVLQVEINLNLQRSALLDYCKAQGIXVVAYTPLRXSVQPPAV 762
P QVE + + LLD+CK++ I +VAY+ L + P V
Sbjct: 185 KPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWV 228
>BC063574-1|AAH63574.1| 323|Homo sapiens aldo-keto reductase family
1, member C2 (dihydrodiol dehydrogenase 2; bile acid
protein.
Length = 323
Score = 174 bits (423), Expect = 4e-43
Identities = 98/224 (43%), Positives = 139/224 (62%), Gaps = 13/224 (5%)
Frame = +1
Query: 130 LKLNNGKEIPGFGIGTWLGTNSNELKGD*VQKSVEWAIDAGYRHIDTAAIYSTEDQVGRA 309
+KLN+G +P G GT+ + K ++V+ AI+AG+ HID+A +Y+ E+QVG A
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKA---LEAVKLAIEAGFHHIDSAHVYNNEEQVGLA 64
Query: 310 IKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLIHWPIAL-- 483
I+ KIA+G VKRED+F T+KLW+ +H+ E V PAL +SLKNL LDYV+LYLIH+P+++
Sbjct: 65 IRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKP 124
Query: 484 -------HENASI--SQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLEXLKSXGGV-- 630
EN I D TW+AM + GL KSIGVSNFN + LE + + G+
Sbjct: 125 GEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKY 184
Query: 631 TPSVLQVEINLNLQRSALLDYCKAQGIXVVAYTPLRXSVQPPAV 762
P QVE + + LLD+CK++ I +VAY+ L + P V
Sbjct: 185 KPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWV 228
>BC007024-1|AAH07024.1| 323|Homo sapiens aldo-keto reductase family
1, member C2 (dihydrodiol dehydrogenase 2; bile acid
protein.
Length = 323
Score = 174 bits (423), Expect = 4e-43
Identities = 98/224 (43%), Positives = 139/224 (62%), Gaps = 13/224 (5%)
Frame = +1
Query: 130 LKLNNGKEIPGFGIGTWLGTNSNELKGD*VQKSVEWAIDAGYRHIDTAAIYSTEDQVGRA 309
+KLN+G +P G GT+ + K ++V+ AI+AG+ HID+A +Y+ E+QVG A
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKA---LEAVKLAIEAGFHHIDSAHVYNNEEQVGLA 64
Query: 310 IKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLIHWPIAL-- 483
I+ KIA+G VKRED+F T+KLW+ +H+ E V PAL +SLKNL LDYV+LYLIH+P+++
Sbjct: 65 IRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKP 124
Query: 484 -------HENASI--SQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLEXLKSXGGV-- 630
EN I D TW+AM + GL KSIGVSNFN + LE + + G+
Sbjct: 125 GEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKY 184
Query: 631 TPSVLQVEINLNLQRSALLDYCKAQGIXVVAYTPLRXSVQPPAV 762
P QVE + + LLD+CK++ I +VAY+ L + P V
Sbjct: 185 KPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWV 228
>AL713867-1|CAI16408.1| 323|Homo sapiens aldo-keto reductase family
1, member C2 (dihydrodiol dehydrogenase 2; bile acid
protein.
Length = 323
Score = 174 bits (423), Expect = 4e-43
Identities = 98/224 (43%), Positives = 139/224 (62%), Gaps = 13/224 (5%)
Frame = +1
Query: 130 LKLNNGKEIPGFGIGTWLGTNSNELKGD*VQKSVEWAIDAGYRHIDTAAIYSTEDQVGRA 309
+KLN+G +P G GT+ + K ++V+ AI+AG+ HID+A +Y+ E+QVG A
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKA---LEAVKLAIEAGFHHIDSAHVYNNEEQVGLA 64
Query: 310 IKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLIHWPIAL-- 483
I+ KIA+G VKRED+F T+KLW+ +H+ E V PAL +SLKNL LDYV+LYLIH+P+++
Sbjct: 65 IRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKP 124
Query: 484 -------HENASI--SQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLEXLKSXGGV-- 630
EN I D TW+AM + GL KSIGVSNFN + LE + + G+
Sbjct: 125 GEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKY 184
Query: 631 TPSVLQVEINLNLQRSALLDYCKAQGIXVVAYTPLRXSVQPPAV 762
P QVE + + LLD+CK++ I +VAY+ L + P V
Sbjct: 185 KPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWV 228
>AL391427-1|CAI14726.1| 323|Homo sapiens aldo-keto reductase family
1, member C2 (dihydrodiol dehydrogenase 2; bile acid
protein.
Length = 323
Score = 174 bits (423), Expect = 4e-43
Identities = 98/224 (43%), Positives = 139/224 (62%), Gaps = 13/224 (5%)
Frame = +1
Query: 130 LKLNNGKEIPGFGIGTWLGTNSNELKGD*VQKSVEWAIDAGYRHIDTAAIYSTEDQVGRA 309
+KLN+G +P G GT+ + K ++V+ AI+AG+ HID+A +Y+ E+QVG A
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKA---LEAVKLAIEAGFHHIDSAHVYNNEEQVGLA 64
Query: 310 IKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLIHWPIAL-- 483
I+ KIA+G VKRED+F T+KLW+ +H+ E V PAL +SLKNL LDYV+LYLIH+P+++
Sbjct: 65 IRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKP 124
Query: 484 -------HENASI--SQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLEXLKSXGGV-- 630
EN I D TW+AM + GL KSIGVSNFN + LE + + G+
Sbjct: 125 GEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKY 184
Query: 631 TPSVLQVEINLNLQRSALLDYCKAQGIXVVAYTPLRXSVQPPAV 762
P QVE + + LLD+CK++ I +VAY+ L + P V
Sbjct: 185 KPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWV 228
>AB209017-1|BAD92254.1| 286|Homo sapiens aldo-keto reductase family
1, member C2 variant protein.
Length = 286
Score = 174 bits (423), Expect = 4e-43
Identities = 98/224 (43%), Positives = 139/224 (62%), Gaps = 13/224 (5%)
Frame = +1
Query: 130 LKLNNGKEIPGFGIGTWLGTNSNELKGD*VQKSVEWAIDAGYRHIDTAAIYSTEDQVGRA 309
+KLN+G +P G GT+ + K ++V+ AI+AG+ HID+A +Y+ E+QVG A
Sbjct: 21 VKLNDGHFMPVLGFGTYAPAEVPKSKA---LEAVKLAIEAGFHHIDSAHVYNNEEQVGLA 77
Query: 310 IKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLIHWPIAL-- 483
I+ KIA+G VKRED+F T+KLW+ +H+ E V PAL +SLKNL LDYV+LYLIH+P+++
Sbjct: 78 IRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKP 137
Query: 484 -------HENASI--SQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLEXLKSXGGV-- 630
EN I D TW+AM + GL KSIGVSNFN + LE + + G+
Sbjct: 138 GEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKY 197
Query: 631 TPSVLQVEINLNLQRSALLDYCKAQGIXVVAYTPLRXSVQPPAV 762
P QVE + + LLD+CK++ I +VAY+ L + P V
Sbjct: 198 KPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWV 241
>AB032153-1|BAA92891.1| 323|Homo sapiens bile acid-binding protein
protein.
Length = 323
Score = 174 bits (423), Expect = 4e-43
Identities = 98/224 (43%), Positives = 139/224 (62%), Gaps = 13/224 (5%)
Frame = +1
Query: 130 LKLNNGKEIPGFGIGTWLGTNSNELKGD*VQKSVEWAIDAGYRHIDTAAIYSTEDQVGRA 309
+KLN+G +P G GT+ + K ++V+ AI+AG+ HID+A +Y+ E+QVG A
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKA---LEAVKLAIEAGFHHIDSAHVYNNEEQVGLA 64
Query: 310 IKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLIHWPIAL-- 483
I+ KIA+G VKRED+F T+KLW+ +H+ E V PAL +SLKNL LDYV+LYLIH+P+++
Sbjct: 65 IRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKP 124
Query: 484 -------HENASI--SQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLEXLKSXGGV-- 630
EN I D TW+AM + GL KSIGVSNFN + LE + + G+
Sbjct: 125 GEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKY 184
Query: 631 TPSVLQVEINLNLQRSALLDYCKAQGIXVVAYTPLRXSVQPPAV 762
P QVE + + LLD+CK++ I +VAY+ L + P V
Sbjct: 185 KPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWV 228
>AB031084-1|BAA92884.1| 323|Homo sapiens bile acid-binding protein
protein.
Length = 323
Score = 174 bits (423), Expect = 4e-43
Identities = 98/224 (43%), Positives = 139/224 (62%), Gaps = 13/224 (5%)
Frame = +1
Query: 130 LKLNNGKEIPGFGIGTWLGTNSNELKGD*VQKSVEWAIDAGYRHIDTAAIYSTEDQVGRA 309
+KLN+G +P G GT+ + K ++V+ AI+AG+ HID+A +Y+ E+QVG A
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKA---LEAVKLAIEAGFHHIDSAHVYNNEEQVGLA 64
Query: 310 IKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLIHWPIAL-- 483
I+ KIA+G VKRED+F T+KLW+ +H+ E V PAL +SLKNL LDYV+LYLIH+P+++
Sbjct: 65 IRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKP 124
Query: 484 -------HENASI--SQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLEXLKSXGGV-- 630
EN I D TW+AM + GL KSIGVSNFN + LE + + G+
Sbjct: 125 GEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKY 184
Query: 631 TPSVLQVEINLNLQRSALLDYCKAQGIXVVAYTPLRXSVQPPAV 762
P QVE + + LLD+CK++ I +VAY+ L + P V
Sbjct: 185 KPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWV 228
>AB021654-1|BAA36169.1| 323|Homo sapiens DD2/bile acid-binding
protein/AKR1C2/3alpha-hydroxysteroid dehydrogenase type
3 protein.
Length = 323
Score = 174 bits (423), Expect = 4e-43
Identities = 98/224 (43%), Positives = 139/224 (62%), Gaps = 13/224 (5%)
Frame = +1
Query: 130 LKLNNGKEIPGFGIGTWLGTNSNELKGD*VQKSVEWAIDAGYRHIDTAAIYSTEDQVGRA 309
+KLN+G +P G GT+ + K ++V+ AI+AG+ HID+A +Y+ E+QVG A
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKA---LEAVKLAIEAGFHHIDSAHVYNNEEQVGLA 64
Query: 310 IKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLIHWPIAL-- 483
I+ KIA+G VKRED+F T+KLW+ +H+ E V PAL +SLKNL LDYV+LYLIH+P+++
Sbjct: 65 IRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKP 124
Query: 484 -------HENASI--SQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLEXLKSXGGV-- 630
EN I D TW+AM + GL KSIGVSNFN + LE + + G+
Sbjct: 125 GEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKY 184
Query: 631 TPSVLQVEINLNLQRSALLDYCKAQGIXVVAYTPLRXSVQPPAV 762
P QVE + + LLD+CK++ I +VAY+ L + P V
Sbjct: 185 KPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWV 228
>U05861-1|AAA18115.1| 323|Homo sapiens hepatic dihydrodiol
dehydrogenase protein.
Length = 323
Score = 173 bits (422), Expect = 6e-43
Identities = 98/224 (43%), Positives = 139/224 (62%), Gaps = 13/224 (5%)
Frame = +1
Query: 130 LKLNNGKEIPGFGIGTWLGTNSNELKGD*VQKSVEWAIDAGYRHIDTAAIYSTEDQVGRA 309
+KLN+G +P G GT+ + K ++ + AI+AG+RHID+A +Y+ E+QVG A
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKA---LEATKLAIEAGFRHIDSAHLYNNEEQVGLA 64
Query: 310 IKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLIHWPIAL-- 483
I+ KIA+G VKRED+F T+KLW +H+ E V PAL +SLKNL LDYV+LYLIH+P+++
Sbjct: 65 IRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKP 124
Query: 484 -------HENASI--SQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLEXLKSXGGV-- 630
EN I D TW+A+ + GL KSIGVSNFN +QLE + + G+
Sbjct: 125 GEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKY 184
Query: 631 TPSVLQVEINLNLQRSALLDYCKAQGIXVVAYTPLRXSVQPPAV 762
P QVE + + LLD+CK++ I +VAY+ L + P V
Sbjct: 185 KPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWV 228
>U05684-1|AAA16227.1| 323|Homo sapiens dihydrodiol dehydrogenase
protein.
Length = 323
Score = 173 bits (422), Expect = 6e-43
Identities = 98/224 (43%), Positives = 139/224 (62%), Gaps = 13/224 (5%)
Frame = +1
Query: 130 LKLNNGKEIPGFGIGTWLGTNSNELKGD*VQKSVEWAIDAGYRHIDTAAIYSTEDQVGRA 309
+KLN+G +P G GT+ + K ++ + AI+AG+RHID+A +Y+ E+QVG A
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKA---LEATKLAIEAGFRHIDSAHLYNNEEQVGLA 64
Query: 310 IKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLIHWPIAL-- 483
I+ KIA+G VKRED+F T+KLW +H+ E V PAL +SLKNL LDYV+LYLIH+P+++
Sbjct: 65 IRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKP 124
Query: 484 -------HENASI--SQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLEXLKSXGGV-- 630
EN I D TW+A+ + GL KSIGVSNFN +QLE + + G+
Sbjct: 125 GEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKY 184
Query: 631 TPSVLQVEINLNLQRSALLDYCKAQGIXVVAYTPLRXSVQPPAV 762
P QVE + + LLD+CK++ I +VAY+ L + P V
Sbjct: 185 KPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWV 228
>M86609-1|AAB02880.1| 323|Homo sapiens dihydrodiol dehydrogenase
protein.
Length = 323
Score = 173 bits (422), Expect = 6e-43
Identities = 98/224 (43%), Positives = 139/224 (62%), Gaps = 13/224 (5%)
Frame = +1
Query: 130 LKLNNGKEIPGFGIGTWLGTNSNELKGD*VQKSVEWAIDAGYRHIDTAAIYSTEDQVGRA 309
+KLN+G +P G GT+ + K ++ + AI+AG+RHID+A +Y+ E+QVG A
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKA---LEATKLAIEAGFRHIDSAHLYNNEEQVGLA 64
Query: 310 IKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLIHWPIAL-- 483
I+ KIA+G VKRED+F T+KLW +H+ E V PAL +SLKNL LDYV+LYLIH+P+++
Sbjct: 65 IRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKP 124
Query: 484 -------HENASI--SQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLEXLKSXGGV-- 630
EN I D TW+A+ + GL KSIGVSNFN +QLE + + G+
Sbjct: 125 GEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKY 184
Query: 631 TPSVLQVEINLNLQRSALLDYCKAQGIXVVAYTPLRXSVQPPAV 762
P QVE + + LLD+CK++ I +VAY+ L + P V
Sbjct: 185 KPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWV 228
>D17793-1|BAA04619.2| 325|Homo sapiens KIAA0119 protein.
Length = 325
Score = 173 bits (422), Expect = 6e-43
Identities = 100/215 (46%), Positives = 132/215 (61%), Gaps = 13/215 (6%)
Frame = +1
Query: 130 LKLNNGKEIPGFGIGTWLGTNSNELKGD*VQKSVEWAIDAGYRHIDTAAIYSTEDQVGRA 309
+KLN+G +P G GT+ K V K AI+AG+RHID+A +Y+ E+QVG A
Sbjct: 10 VKLNDGHFMPVLGFGTYAPPEVPRSKALEVTKL---AIEAGFRHIDSAHLYNNEEQVGLA 66
Query: 310 IKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLIHWPIALHE 489
I+ KIA+G VKRED+F T+KLW+T H+ E V PAL SLK LDYV+LYLIH P++L
Sbjct: 67 IRSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLKP 126
Query: 490 NASISQT-----------DYVETWQAMTDVLNQGLTKSIGVSNFNIQQLEXLKSXGGV-- 630
+S T D TW+AM + GL KSIGVSNFN +QLE + + G+
Sbjct: 127 GEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKY 186
Query: 631 TPSVLQVEINLNLQRSALLDYCKAQGIXVVAYTPL 735
P QVE + RS LLD+CK++ I +VAY+ L
Sbjct: 187 KPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSAL 221
>BT007286-1|AAP35950.1| 323|Homo sapiens aldo-keto reductase family
1, member C3 (3-alpha hydroxysteroid dehydrogenase,
protein.
Length = 323
Score = 173 bits (422), Expect = 6e-43
Identities = 100/215 (46%), Positives = 132/215 (61%), Gaps = 13/215 (6%)
Frame = +1
Query: 130 LKLNNGKEIPGFGIGTWLGTNSNELKGD*VQKSVEWAIDAGYRHIDTAAIYSTEDQVGRA 309
+KLN+G +P G GT+ K V K AI+AG+RHID+A +Y+ E+QVG A
Sbjct: 8 VKLNDGHFMPVLGFGTYAPPEVPRSKALEVTKL---AIEAGFRHIDSAHLYNNEEQVGLA 64
Query: 310 IKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLIHWPIALHE 489
I+ KIA+G VKRED+F T+KLW+T H+ E V PAL SLK LDYV+LYLIH P++L
Sbjct: 65 IRSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLKP 124
Query: 490 NASISQT-----------DYVETWQAMTDVLNQGLTKSIGVSNFNIQQLEXLKSXGGV-- 630
+S T D TW+AM + GL KSIGVSNFN +QLE + + G+
Sbjct: 125 GEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKY 184
Query: 631 TPSVLQVEINLNLQRSALLDYCKAQGIXVVAYTPL 735
P QVE + RS LLD+CK++ I +VAY+ L
Sbjct: 185 KPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSAL 219
>BT007197-1|AAP35861.1| 323|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 323
Score = 173 bits (422), Expect = 6e-43
Identities = 98/224 (43%), Positives = 139/224 (62%), Gaps = 13/224 (5%)
Frame = +1
Query: 130 LKLNNGKEIPGFGIGTWLGTNSNELKGD*VQKSVEWAIDAGYRHIDTAAIYSTEDQVGRA 309
+KLN+G +P G GT+ + K ++ + AI+AG+RHID+A +Y+ E+QVG A
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKA---LEATKLAIEAGFRHIDSAHLYNNEEQVGLA 64
Query: 310 IKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLIHWPIAL-- 483
I+ KIA+G VKRED+F T+KLW +H+ E V PAL +SLKNL LDYV+LYLIH+P+++
Sbjct: 65 IRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKP 124
Query: 484 -------HENASI--SQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLEXLKSXGGV-- 630
EN I D TW+A+ + GL KSIGVSNFN +QLE + + G+
Sbjct: 125 GEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKY 184
Query: 631 TPSVLQVEINLNLQRSALLDYCKAQGIXVVAYTPLRXSVQPPAV 762
P QVE + + LLD+CK++ I +VAY+ L + P V
Sbjct: 185 KPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWV 228
>BC040210-1|AAH40210.1| 323|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 323
Score = 173 bits (422), Expect = 6e-43
Identities = 98/224 (43%), Positives = 139/224 (62%), Gaps = 13/224 (5%)
Frame = +1
Query: 130 LKLNNGKEIPGFGIGTWLGTNSNELKGD*VQKSVEWAIDAGYRHIDTAAIYSTEDQVGRA 309
+KLN+G +P G GT+ + K ++ + AI+AG+RHID+A +Y+ E+QVG A
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKA---LEATKLAIEAGFRHIDSAHLYNNEEQVGLA 64
Query: 310 IKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLIHWPIAL-- 483
I+ KIA+G VKRED+F T+KLW +H+ E V PAL +SLKNL LDYV+LYLIH+P+++
Sbjct: 65 IRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKP 124
Query: 484 -------HENASI--SQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLEXLKSXGGV-- 630
EN I D TW+A+ + GL KSIGVSNFN +QLE + + G+
Sbjct: 125 GEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKY 184
Query: 631 TPSVLQVEINLNLQRSALLDYCKAQGIXVVAYTPLRXSVQPPAV 762
P QVE + + LLD+CK++ I +VAY+ L + P V
Sbjct: 185 KPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWV 228
>BC020216-1|AAH20216.1| 323|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 323
Score = 173 bits (422), Expect = 6e-43
Identities = 98/224 (43%), Positives = 139/224 (62%), Gaps = 13/224 (5%)
Frame = +1
Query: 130 LKLNNGKEIPGFGIGTWLGTNSNELKGD*VQKSVEWAIDAGYRHIDTAAIYSTEDQVGRA 309
+KLN+G +P G GT+ + K ++ + AI+AG+RHID+A +Y+ E+QVG A
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKA---LEATKLAIEAGFRHIDSAHLYNNEEQVGLA 64
Query: 310 IKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLIHWPIAL-- 483
I+ KIA+G VKRED+F T+KLW +H+ E V PAL +SLKNL LDYV+LYLIH+P+++
Sbjct: 65 IRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKP 124
Query: 484 -------HENASI--SQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLEXLKSXGGV-- 630
EN I D TW+A+ + GL KSIGVSNFN +QLE + + G+
Sbjct: 125 GEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKY 184
Query: 631 TPSVLQVEINLNLQRSALLDYCKAQGIXVVAYTPLRXSVQPPAV 762
P QVE + + LLD+CK++ I +VAY+ L + P V
Sbjct: 185 KPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWV 228
>BC019230-1|AAH19230.1| 323|Homo sapiens aldo-keto reductase family
1, member C3 (3-alpha hydroxysteroid dehydrogenase,
protein.
Length = 323
Score = 173 bits (422), Expect = 6e-43
Identities = 100/215 (46%), Positives = 132/215 (61%), Gaps = 13/215 (6%)
Frame = +1
Query: 130 LKLNNGKEIPGFGIGTWLGTNSNELKGD*VQKSVEWAIDAGYRHIDTAAIYSTEDQVGRA 309
+KLN+G +P G GT+ K V K AI+AG+RHID+A +Y+ E+QVG A
Sbjct: 8 VKLNDGHFMPVLGFGTYAPPEVPRSKALEVTKL---AIEAGFRHIDSAHLYNNEEQVGLA 64
Query: 310 IKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLIHWPIALHE 489
I+ KIA+G VKRED+F T+KLW+T H+ E V PAL SLK LDYV+LYLIH P++L
Sbjct: 65 IRSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLKP 124
Query: 490 NASISQT-----------DYVETWQAMTDVLNQGLTKSIGVSNFNIQQLEXLKSXGGV-- 630
+S T D TW+AM + GL KSIGVSNFN +QLE + + G+
Sbjct: 125 GEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKY 184
Query: 631 TPSVLQVEINLNLQRSALLDYCKAQGIXVVAYTPL 735
P QVE + RS LLD+CK++ I +VAY+ L
Sbjct: 185 KPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSAL 219
>BC015490-1|AAH15490.1| 323|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 323
Score = 173 bits (422), Expect = 6e-43
Identities = 98/224 (43%), Positives = 139/224 (62%), Gaps = 13/224 (5%)
Frame = +1
Query: 130 LKLNNGKEIPGFGIGTWLGTNSNELKGD*VQKSVEWAIDAGYRHIDTAAIYSTEDQVGRA 309
+KLN+G +P G GT+ + K ++ + AI+AG+RHID+A +Y+ E+QVG A
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKA---LEATKLAIEAGFRHIDSAHLYNNEEQVGLA 64
Query: 310 IKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLIHWPIAL-- 483
I+ KIA+G VKRED+F T+KLW +H+ E V PAL +SLKNL LDYV+LYLIH+P+++
Sbjct: 65 IRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKP 124
Query: 484 -------HENASI--SQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLEXLKSXGGV-- 630
EN I D TW+A+ + GL KSIGVSNFN +QLE + + G+
Sbjct: 125 GEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKY 184
Query: 631 TPSVLQVEINLNLQRSALLDYCKAQGIXVVAYTPLRXSVQPPAV 762
P QVE + + LLD+CK++ I +VAY+ L + P V
Sbjct: 185 KPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWV 228
>BC001479-1|AAH01479.1| 323|Homo sapiens aldo-keto reductase family
1, member C3 (3-alpha hydroxysteroid dehydrogenase,
protein.
Length = 323
Score = 173 bits (422), Expect = 6e-43
Identities = 100/215 (46%), Positives = 132/215 (61%), Gaps = 13/215 (6%)
Frame = +1
Query: 130 LKLNNGKEIPGFGIGTWLGTNSNELKGD*VQKSVEWAIDAGYRHIDTAAIYSTEDQVGRA 309
+KLN+G +P G GT+ K V K AI+AG+RHID+A +Y+ E+QVG A
Sbjct: 8 VKLNDGHFMPVLGFGTYAPPEVPRSKALEVTKL---AIEAGFRHIDSAHLYNNEEQVGLA 64
Query: 310 IKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLIHWPIALHE 489
I+ KIA+G VKRED+F T+KLW+T H+ E V PAL SLK LDYV+LYLIH P++L
Sbjct: 65 IRSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLKP 124
Query: 490 NASISQT-----------DYVETWQAMTDVLNQGLTKSIGVSNFNIQQLEXLKSXGGV-- 630
+S T D TW+AM + GL KSIGVSNFN +QLE + + G+
Sbjct: 125 GEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKY 184
Query: 631 TPSVLQVEINLNLQRSALLDYCKAQGIXVVAYTPL 735
P QVE + RS LLD+CK++ I +VAY+ L
Sbjct: 185 KPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSAL 219
>AL713867-2|CAI16409.1| 323|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 323
Score = 173 bits (422), Expect = 6e-43
Identities = 98/224 (43%), Positives = 139/224 (62%), Gaps = 13/224 (5%)
Frame = +1
Query: 130 LKLNNGKEIPGFGIGTWLGTNSNELKGD*VQKSVEWAIDAGYRHIDTAAIYSTEDQVGRA 309
+KLN+G +P G GT+ + K ++ + AI+AG+RHID+A +Y+ E+QVG A
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKA---LEATKLAIEAGFRHIDSAHLYNNEEQVGLA 64
Query: 310 IKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLIHWPIAL-- 483
I+ KIA+G VKRED+F T+KLW +H+ E V PAL +SLKNL LDYV+LYLIH+P+++
Sbjct: 65 IRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKP 124
Query: 484 -------HENASI--SQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLEXLKSXGGV-- 630
EN I D TW+A+ + GL KSIGVSNFN +QLE + + G+
Sbjct: 125 GEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKY 184
Query: 631 TPSVLQVEINLNLQRSALLDYCKAQGIXVVAYTPLRXSVQPPAV 762
P QVE + + LLD+CK++ I +VAY+ L + P V
Sbjct: 185 KPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWV 228
>AL391427-4|CAI14729.1| 323|Homo sapiens aldo-keto reductase family
1, member C3 (3-alpha hydroxysteroid dehydrogenase,
protein.
Length = 323
Score = 173 bits (422), Expect = 6e-43
Identities = 100/215 (46%), Positives = 132/215 (61%), Gaps = 13/215 (6%)
Frame = +1
Query: 130 LKLNNGKEIPGFGIGTWLGTNSNELKGD*VQKSVEWAIDAGYRHIDTAAIYSTEDQVGRA 309
+KLN+G +P G GT+ K V K AI+AG+RHID+A +Y+ E+QVG A
Sbjct: 8 VKLNDGHFMPVLGFGTYAPPEVPRSKALEVTKL---AIEAGFRHIDSAHLYNNEEQVGLA 64
Query: 310 IKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLIHWPIALHE 489
I+ KIA+G VKRED+F T+KLW+T H+ E V PAL SLK LDYV+LYLIH P++L
Sbjct: 65 IRSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLKP 124
Query: 490 NASISQT-----------DYVETWQAMTDVLNQGLTKSIGVSNFNIQQLEXLKSXGGV-- 630
+S T D TW+AM + GL KSIGVSNFN +QLE + + G+
Sbjct: 125 GEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKY 184
Query: 631 TPSVLQVEINLNLQRSALLDYCKAQGIXVVAYTPL 735
P QVE + RS LLD+CK++ I +VAY+ L
Sbjct: 185 KPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSAL 219
>AB032157-1|BAA92892.1| 323|Homo sapiens prostaglandin F synthase
protein.
Length = 323
Score = 173 bits (422), Expect = 6e-43
Identities = 100/215 (46%), Positives = 132/215 (61%), Gaps = 13/215 (6%)
Frame = +1
Query: 130 LKLNNGKEIPGFGIGTWLGTNSNELKGD*VQKSVEWAIDAGYRHIDTAAIYSTEDQVGRA 309
+KLN+G +P G GT+ K V K AI+AG+RHID+A +Y+ E+QVG A
Sbjct: 8 VKLNDGHFMPVLGFGTYAPPEVPRSKALEVTKL---AIEAGFRHIDSAHLYNNEEQVGLA 64
Query: 310 IKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLIHWPIALHE 489
I+ KIA+G VKRED+F T+KLW+T H+ E V PAL SLK LDYV+LYLIH P++L
Sbjct: 65 IRSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLKP 124
Query: 490 NASISQT-----------DYVETWQAMTDVLNQGLTKSIGVSNFNIQQLEXLKSXGGV-- 630
+S T D TW+AM + GL KSIGVSNFN +QLE + + G+
Sbjct: 125 GEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKY 184
Query: 631 TPSVLQVEINLNLQRSALLDYCKAQGIXVVAYTPL 735
P QVE + RS LLD+CK++ I +VAY+ L
Sbjct: 185 KPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSAL 219
>AB032150-1|BAA92886.1| 323|Homo sapiens 20 alph-hydroxysteroid
dehydrogenase protein.
Length = 323
Score = 173 bits (422), Expect = 6e-43
Identities = 98/224 (43%), Positives = 139/224 (62%), Gaps = 13/224 (5%)
Frame = +1
Query: 130 LKLNNGKEIPGFGIGTWLGTNSNELKGD*VQKSVEWAIDAGYRHIDTAAIYSTEDQVGRA 309
+KLN+G +P G GT+ + K ++ + AI+AG+RHID+A +Y+ E+QVG A
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKA---LEATKLAIEAGFRHIDSAHLYNNEEQVGLA 64
Query: 310 IKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLIHWPIAL-- 483
I+ KIA+G VKRED+F T+KLW +H+ E V PAL +SLKNL LDYV+LYLIH+P+++
Sbjct: 65 IRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKP 124
Query: 484 -------HENASI--SQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLEXLKSXGGV-- 630
EN I D TW+A+ + GL KSIGVSNFN +QLE + + G+
Sbjct: 125 GEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKY 184
Query: 631 TPSVLQVEINLNLQRSALLDYCKAQGIXVVAYTPLRXSVQPPAV 762
P QVE + + LLD+CK++ I +VAY+ L + P V
Sbjct: 185 KPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWV 228
>AB031083-1|BAA92883.1| 323|Homo sapiens 20 alpha-hydroxysteroid
dehydrogenase protein.
Length = 323
Score = 173 bits (422), Expect = 6e-43
Identities = 98/224 (43%), Positives = 139/224 (62%), Gaps = 13/224 (5%)
Frame = +1
Query: 130 LKLNNGKEIPGFGIGTWLGTNSNELKGD*VQKSVEWAIDAGYRHIDTAAIYSTEDQVGRA 309
+KLN+G +P G GT+ + K ++ + AI+AG+RHID+A +Y+ E+QVG A
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKA---LEATKLAIEAGFRHIDSAHLYNNEEQVGLA 64
Query: 310 IKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLIHWPIAL-- 483
I+ KIA+G VKRED+F T+KLW +H+ E V PAL +SLKNL LDYV+LYLIH+P+++
Sbjct: 65 IRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKP 124
Query: 484 -------HENASI--SQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLEXLKSXGGV-- 630
EN I D TW+A+ + GL KSIGVSNFN +QLE + + G+
Sbjct: 125 GEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKY 184
Query: 631 TPSVLQVEINLNLQRSALLDYCKAQGIXVVAYTPLRXSVQPPAV 762
P QVE + + LLD+CK++ I +VAY+ L + P V
Sbjct: 185 KPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWV 228
>AB018580-1|BAA88488.1| 323|Homo sapiens hluPGFS protein.
Length = 323
Score = 173 bits (422), Expect = 6e-43
Identities = 100/215 (46%), Positives = 132/215 (61%), Gaps = 13/215 (6%)
Frame = +1
Query: 130 LKLNNGKEIPGFGIGTWLGTNSNELKGD*VQKSVEWAIDAGYRHIDTAAIYSTEDQVGRA 309
+KLN+G +P G GT+ K V K AI+AG+RHID+A +Y+ E+QVG A
Sbjct: 8 VKLNDGHFMPVLGFGTYAPPEVPRSKALEVTKL---AIEAGFRHIDSAHLYNNEEQVGLA 64
Query: 310 IKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLIHWPIALHE 489
I+ KIA+G VKRED+F T+KLW+T H+ E V PAL SLK LDYV+LYLIH P++L
Sbjct: 65 IRSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLKP 124
Query: 490 NASISQT-----------DYVETWQAMTDVLNQGLTKSIGVSNFNIQQLEXLKSXGGV-- 630
+S T D TW+AM + GL KSIGVSNFN +QLE + + G+
Sbjct: 125 GEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKY 184
Query: 631 TPSVLQVEINLNLQRSALLDYCKAQGIXVVAYTPL 735
P QVE + RS LLD+CK++ I +VAY+ L
Sbjct: 185 KPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSAL 219
>DQ269985-1|ABB76132.1| 323|Homo sapiens type II 3a-hydroxysteroid
dehydrogenase variant protein.
Length = 323
Score = 173 bits (421), Expect = 7e-43
Identities = 96/215 (44%), Positives = 134/215 (62%), Gaps = 13/215 (6%)
Frame = +1
Query: 130 LKLNNGKEIPGFGIGTWLGTNSNELKGD*VQKSVEWAIDAGYRHIDTAAIYSTEDQVGRA 309
+KLN+G +P G GT+ + K ++ + AI+AG+RHID+A +Y+ E+QVG A
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKA---LEATKLAIEAGFRHIDSAHLYNNEEQVGLA 64
Query: 310 IKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLIHWPIALHE 489
++ KIA+G VKRED+F T+KLW +H+ E V PAL +SLK LDYV+LYLIH P++L
Sbjct: 65 VRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKKAQLDYVDLYLIHSPMSLKP 124
Query: 490 NASISQT-----------DYVETWQAMTDVLNQGLTKSIGVSNFNIQQLEXLKSXGGV-- 630
+S T D TW+AM + GL KSIGVSNFN +QLE + + G+
Sbjct: 125 GEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKY 184
Query: 631 TPSVLQVEINLNLQRSALLDYCKAQGIXVVAYTPL 735
P QVE + RS LLD+CK++ I +VAY+ L
Sbjct: 185 KPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSAL 219
>S68288-1|AAD14011.1| 323|Homo sapiens chlordecone reductase
homolog protein.
Length = 323
Score = 172 bits (418), Expect = 2e-42
Identities = 99/215 (46%), Positives = 132/215 (61%), Gaps = 13/215 (6%)
Frame = +1
Query: 130 LKLNNGKEIPGFGIGTWLGTNSNELKGD*VQKSVEWAIDAGYRHIDTAAIYSTEDQVGRA 309
+KLN+G +P G GT+ K V K AI+AG+RHID+A +Y+ E+QVG A
Sbjct: 8 VKLNDGHFMPVLGFGTYAPPEVPRSKALEVTKL---AIEAGFRHIDSAHLYNNEEQVGLA 64
Query: 310 IKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLIHWPIALHE 489
I+ KIA+G V+RED+F T+KLW+T H+ E V PAL SLK LDYV+LYLIH P++L
Sbjct: 65 IRSKIADGSVEREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLKP 124
Query: 490 NASISQT-----------DYVETWQAMTDVLNQGLTKSIGVSNFNIQQLEXLKSXGGV-- 630
+S T D TW+AM + GL KSIGVSNFN +QLE + + G+
Sbjct: 125 GEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEIILNKPGLKY 184
Query: 631 TPSVLQVEINLNLQRSALLDYCKAQGIXVVAYTPL 735
P QVE + RS LLD+CK++ I +VAY+ L
Sbjct: 185 KPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSAL 219
>BC005387-1|AAH05387.1| 316|Homo sapiens aldo-keto reductase family
1, member B1 (aldose reductase) protein.
Length = 316
Score = 171 bits (417), Expect = 2e-42
Identities = 94/225 (41%), Positives = 143/225 (63%), Gaps = 13/225 (5%)
Frame = +1
Query: 118 LAPVLKLNNGKEIPGFGIGTWLGTNSNELKGD*VQKSVEWAIDAGYRHIDTAAIYSTEDQ 297
+A L LNNG ++P G+GTW V ++V+ AID GYRHID A +Y E++
Sbjct: 1 MASRLLLNNGAKMPILGLGTWKSPPGQ------VTEAVKVAIDVGYRHIDCAHVYQNENE 54
Query: 298 VGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLIHWP- 474
VG AI++K+ E VVKRE+LF+ +KLW T H+K V A +K+L +L LDY++LYLIHWP
Sbjct: 55 VGVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPT 114
Query: 475 --------IALHENASI--SQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLEXLKSXG 624
L E+ ++ S T+ ++T AM +++++GL K+IG+SNFN Q+E + +
Sbjct: 115 GFKPGKEFFPLDESGNVVPSDTNILDTRAAMEELVDEGLVKAIGISNFNHLQVEMILNKP 174
Query: 625 GV--TPSVLQVEINLNLQRSALLDYCKAQGIXVVAYTPLRXSVQP 753
G+ P+V Q+E + L + L+ YC+++GI V AY+PL +P
Sbjct: 175 GLKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRP 219
>L43839-1|AAB41916.1| 323|Homo sapiens 3-alpha-hydroxysteroid
dehydrogenase protein.
Length = 323
Score = 171 bits (416), Expect = 3e-42
Identities = 99/215 (46%), Positives = 131/215 (60%), Gaps = 13/215 (6%)
Frame = +1
Query: 130 LKLNNGKEIPGFGIGTWLGTNSNELKGD*VQKSVEWAIDAGYRHIDTAAIYSTEDQVGRA 309
+KLN+G +P G GT+ K V K AI+AG+RHID+A +Y+ E+QVG A
Sbjct: 8 VKLNDGHFMPVLGFGTYAPPEVPRSKALEVTKL---AIEAGFRHIDSAHLYNNEEQVGLA 64
Query: 310 IKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLIHWPIALHE 489
I+ KIA+G V RED+F T+KLW+T H+ E V PAL SLK LDYV+LYLIH P++L
Sbjct: 65 IRSKIADGSVMREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLKP 124
Query: 490 NASISQT-----------DYVETWQAMTDVLNQGLTKSIGVSNFNIQQLEXLKSXGGV-- 630
+S T D TW+AM + GL KSIGVSNFN +QLE + + G+
Sbjct: 125 GEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEIILNKPGLKY 184
Query: 631 TPSVLQVEINLNLQRSALLDYCKAQGIXVVAYTPL 735
P QVE + RS LLD+CK++ I +VAY+ L
Sbjct: 185 KPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSAL 219
>S68290-1|AAD14012.1| 320|Homo sapiens chlordecone reductase
homolog protein.
Length = 320
Score = 165 bits (402), Expect = 1e-40
Identities = 96/224 (42%), Positives = 135/224 (60%), Gaps = 13/224 (5%)
Frame = +1
Query: 130 LKLNNGKEIPGFGIGTWLGTNSNELKGD*VQKSVEWAIDAGYRHIDTAAIYSTEDQVGRA 309
+KLN+G +P G GT+ + K ++ + AI+AG+RHID+A +Y+ E+QVG A
Sbjct: 5 VKLNDGHFMPVLGFGTYAPAEVPKSKA---LEATKLAIEAGFRHIDSAHLYNNEEQVGLA 61
Query: 310 IKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLIHWPIAL-- 483
I+ KIA+G VKRED+F T+KLW +H+ E PAL +SLKNL LDYV+LYLIH+P+++
Sbjct: 62 IRSKIADGSVKREDIFYTSKLWCNSHRPELDRPALERSLKNLQLDYVDLYLIHFPVSVKP 121
Query: 484 -------HENASI--SQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLEXLKSXGG--V 630
EN I D TW+A+ + L KSIGVSNFN LE + + G V
Sbjct: 122 GEEVIPKDENGKILFDTVDLCATWEAVEKCKDAELAKSIGVSNFNRSTLEMILNKPGLQV 181
Query: 631 TPSVLQVEINLNLQRSALLDYCKAQGIXVVAYTPLRXSVQPPAV 762
P QVE + + LLD+CK++ I +VAY+ L + P V
Sbjct: 182 KPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSLREEPWV 225
>D26124-1|BAA05121.1| 306|Homo sapiens dihydrodiol dehydrogenase
isoform DD1 protein.
Length = 306
Score = 164 bits (399), Expect = 3e-40
Identities = 89/193 (46%), Positives = 125/193 (64%), Gaps = 13/193 (6%)
Frame = +1
Query: 223 KSVEWAIDAGYRHIDTAAIYSTEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAV 402
++ + AI+AG+RHID+A +Y+ E+QVG AI+ KIA+G VKRED+F T+KLW +H+ E V
Sbjct: 19 EATKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELV 78
Query: 403 LPALRKSLKNLDLDYVNLYLIHWPIAL---------HENASI--SQTDYVETWQAMTDVL 549
PAL +SLKNL LDYV+LYLIH+P+++ EN I D TW+A+
Sbjct: 79 RPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCK 138
Query: 550 NQGLTKSIGVSNFNIQQLEXLKSXGGV--TPSVLQVEINLNLQRSALLDYCKAQGIXVVA 723
+ GL KSIGVSNFN +QLE + + G+ P QVE + + LLD+CK++ I +VA
Sbjct: 139 DAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVA 198
Query: 724 YTPLRXSVQPPAV 762
Y+ L + P V
Sbjct: 199 YSALGSHREEPWV 211
>AB045829-1|BAA99542.1| 323|Homo sapiens 3alpha-hydroxysteroid
dehydrogenase variant protein.
Length = 323
Score = 164 bits (399), Expect = 3e-40
Identities = 94/215 (43%), Positives = 134/215 (62%), Gaps = 13/215 (6%)
Frame = +1
Query: 130 LKLNNGKEIPGFGIGTWLGTNSNELKGD*VQKSVEWAIDAGYRHIDTAAIYSTEDQVGRA 309
++LN+G +P G GT+ E+ + + + AI+AG+RHID+A +Y+ E+QVG A
Sbjct: 8 VELNDGHFMPVLGFGTYAPP---EVPRNRAVEVTKLAIEAGFRHIDSAYLYNNEEQVGLA 64
Query: 310 IKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLIHWPIAL-- 483
I+ KIA+G VKRED+F T+KLW T + + V PAL SLK L LDYV+LYL+H+P+AL
Sbjct: 65 IRSKIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALKP 124
Query: 484 -------HENASI--SQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLEXLKSXGGV-- 630
EN + D TW+ M + GL KSIGVSNFN +QLE + + G+
Sbjct: 125 GETPLPKDENGKVIFDTVDLCATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILNKPGLKY 184
Query: 631 TPSVLQVEINLNLQRSALLDYCKAQGIXVVAYTPL 735
P QVE + L +S LLD+CK++ I +VA++ L
Sbjct: 185 KPVCNQVECHPYLNQSKLLDFCKSKDIVLVAHSAL 219
>S68287-1|AAD14010.1| 323|Homo sapiens chlordecone reductase
protein.
Length = 323
Score = 164 bits (398), Expect = 4e-40
Identities = 94/215 (43%), Positives = 134/215 (62%), Gaps = 13/215 (6%)
Frame = +1
Query: 130 LKLNNGKEIPGFGIGTWLGTNSNELKGD*VQKSVEWAIDAGYRHIDTAAIYSTEDQVGRA 309
++LN+G +P G GT+ E+ + + + AI+AG+RHID+A +Y+ E+QVG A
Sbjct: 8 VELNDGHFMPVLGFGTYAPP---EVPRNRAVEVTKLAIEAGFRHIDSAYLYNNEEQVGLA 64
Query: 310 IKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLIHWPIAL-- 483
I+ KIA+G VKRED+F T+KLW T + + V PAL SLK L LDYV+LYL+H+P+AL
Sbjct: 65 IRSKIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALKP 124
Query: 484 -------HENASI--SQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLEXLKSXGGV-- 630
EN + D TW+ M + GL KSIGVSNFN +QLE + + G+
Sbjct: 125 GETPLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILNKPGLKY 184
Query: 631 TPSVLQVEINLNLQRSALLDYCKAQGIXVVAYTPL 735
P QVE + L +S LLD+CK++ I +VA++ L
Sbjct: 185 KPVCNQVECHPYLNQSKLLDFCKSKDIVLVAHSAL 219
>D26125-1|BAA05122.1| 321|Homo sapiens 3
alpha-hydroxysteroid/dihydrodiol dehydrogenase DD4
protein.
Length = 321
Score = 164 bits (398), Expect = 4e-40
Identities = 94/215 (43%), Positives = 134/215 (62%), Gaps = 13/215 (6%)
Frame = +1
Query: 130 LKLNNGKEIPGFGIGTWLGTNSNELKGD*VQKSVEWAIDAGYRHIDTAAIYSTEDQVGRA 309
++LN+G +P G GT+ E+ + + + AI+AG+RHID+A +Y+ E+QVG A
Sbjct: 6 VELNDGHFMPVLGFGTYAPP---EVPRNRAVEVTKLAIEAGFRHIDSAYLYNNEEQVGLA 62
Query: 310 IKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLIHWPIAL-- 483
I+ KIA+G VKRED+F T+KLW T + + V PAL SLK L LDYV+LYL+H+P+AL
Sbjct: 63 IRSKIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALKP 122
Query: 484 -------HENASI--SQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLEXLKSXGGV-- 630
EN + D TW+ M + GL KSIGVSNFN +QLE + + G+
Sbjct: 123 GETPLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILNKPGLKY 182
Query: 631 TPSVLQVEINLNLQRSALLDYCKAQGIXVVAYTPL 735
P QVE + L +S LLD+CK++ I +VA++ L
Sbjct: 183 KPVCNQVECHPYLNQSKLLDFCKSKDIVLVAHSAL 217
>BC020744-1|AAH20744.1| 323|Homo sapiens aldo-keto reductase family
1, member C4 (chlordecone reductase; 3-alpha hydroxy
protein.
Length = 323
Score = 164 bits (398), Expect = 4e-40
Identities = 94/215 (43%), Positives = 134/215 (62%), Gaps = 13/215 (6%)
Frame = +1
Query: 130 LKLNNGKEIPGFGIGTWLGTNSNELKGD*VQKSVEWAIDAGYRHIDTAAIYSTEDQVGRA 309
++LN+G +P G GT+ E+ + + + AI+AG+RHID+A +Y+ E+QVG A
Sbjct: 8 VELNDGHFMPVLGFGTYAPP---EVPRNRAVEVTKLAIEAGFRHIDSAYLYNNEEQVGLA 64
Query: 310 IKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLIHWPIAL-- 483
I+ KIA+G VKRED+F T+KLW T + + V PAL SLK L LDYV+LYL+H+P+AL
Sbjct: 65 IRSKIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALKP 124
Query: 484 -------HENASI--SQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLEXLKSXGGV-- 630
EN + D TW+ M + GL KSIGVSNFN +QLE + + G+
Sbjct: 125 GETPLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNYRQLEMILNKPGLKY 184
Query: 631 TPSVLQVEINLNLQRSALLDYCKAQGIXVVAYTPL 735
P QVE + L +S LLD+CK++ I +VA++ L
Sbjct: 185 KPVCNQVECHPYLNQSKLLDFCKSKDIVLVAHSAL 219
>AL355303-2|CAI14202.1| 323|Homo sapiens aldo-keto reductase family
1, member C4 (chlordecone reductase; 3-alpha hydroxy
protein.
Length = 323
Score = 164 bits (398), Expect = 4e-40
Identities = 94/215 (43%), Positives = 134/215 (62%), Gaps = 13/215 (6%)
Frame = +1
Query: 130 LKLNNGKEIPGFGIGTWLGTNSNELKGD*VQKSVEWAIDAGYRHIDTAAIYSTEDQVGRA 309
++LN+G +P G GT+ E+ + + + AI+AG+RHID+A +Y+ E+QVG A
Sbjct: 8 VELNDGHFMPVLGFGTYAPP---EVPRNRAVEVTKLAIEAGFRHIDSAYLYNNEEQVGLA 64
Query: 310 IKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLIHWPIAL-- 483
I+ KIA+G VKRED+F T+KLW T + + V PAL SLK L LDYV+LYL+H+P+AL
Sbjct: 65 IRSKIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALKP 124
Query: 484 -------HENASI--SQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLEXLKSXGGV-- 630
EN + D TW+ M + GL KSIGVSNFN +QLE + + G+
Sbjct: 125 GETPLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILNKPGLKY 184
Query: 631 TPSVLQVEINLNLQRSALLDYCKAQGIXVVAYTPL 735
P QVE + L +S LLD+CK++ I +VA++ L
Sbjct: 185 KPVCNQVECHPYLNQSKLLDFCKSKDIVLVAHSAL 219
>AB032163-1|BAA92893.1| 323|Homo sapiens dihydrodiol dehydrogenase
4 protein.
Length = 323
Score = 164 bits (398), Expect = 4e-40
Identities = 94/215 (43%), Positives = 134/215 (62%), Gaps = 13/215 (6%)
Frame = +1
Query: 130 LKLNNGKEIPGFGIGTWLGTNSNELKGD*VQKSVEWAIDAGYRHIDTAAIYSTEDQVGRA 309
++LN+G +P G GT+ E+ + + + AI+AG+RHID+A +Y+ E+QVG A
Sbjct: 8 VELNDGHFMPVLGFGTYAPP---EVPRNRAVEVTKLAIEAGFRHIDSAYLYNNEEQVGLA 64
Query: 310 IKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLIHWPIAL-- 483
I+ KIA+G VKRED+F T+KLW T + + V PAL SLK L LDYV+LYL+H+P+AL
Sbjct: 65 IRSKIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALKP 124
Query: 484 -------HENASI--SQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLEXLKSXGGV-- 630
EN + D TW+ M + GL KSIGVSNFN +QLE + + G+
Sbjct: 125 GETPLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILNKPGLKY 184
Query: 631 TPSVLQVEINLNLQRSALLDYCKAQGIXVVAYTPL 735
P QVE + L +S LLD+CK++ I +VA++ L
Sbjct: 185 KPVCNQVECHPYLNQSKLLDFCKSKDIVLVAHSAL 219
>AB031085-1|BAA92885.1| 323|Homo sapiens dihydrodiol dehydrogenase
4 protein.
Length = 323
Score = 164 bits (398), Expect = 4e-40
Identities = 94/215 (43%), Positives = 134/215 (62%), Gaps = 13/215 (6%)
Frame = +1
Query: 130 LKLNNGKEIPGFGIGTWLGTNSNELKGD*VQKSVEWAIDAGYRHIDTAAIYSTEDQVGRA 309
++LN+G +P G GT+ E+ + + + AI+AG+RHID+A +Y+ E+QVG A
Sbjct: 8 VELNDGHFMPVLGFGTYAPP---EVPRNRAVEVTKLAIEAGFRHIDSAYLYNNEEQVGLA 64
Query: 310 IKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLIHWPIAL-- 483
I+ KIA+G VKRED+F T+KLW T + + V PAL SLK L LDYV+LYL+H+P+AL
Sbjct: 65 IRSKIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALKP 124
Query: 484 -------HENASI--SQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLEXLKSXGGV-- 630
EN + D TW+ M + GL KSIGVSNFN +QLE + + G+
Sbjct: 125 GETPLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILNKPGLKY 184
Query: 631 TPSVLQVEINLNLQRSALLDYCKAQGIXVVAYTPL 735
P QVE + L +S LLD+CK++ I +VA++ L
Sbjct: 185 KPVCNQVECHPYLNQSKLLDFCKSKDIVLVAHSAL 219
>U37100-1|AAC17469.1| 316|Homo sapiens aldose reductase-like
peptide protein.
Length = 316
Score = 158 bits (384), Expect = 2e-38
Identities = 87/225 (38%), Positives = 134/225 (59%), Gaps = 13/225 (5%)
Frame = +1
Query: 118 LAPVLKLNNGKEIPGFGIGTWLGTNSNELKGD*VQKSVEWAIDAGYRHIDTAAIYSTEDQ 297
+A ++L+ ++P G+GTW V+++V+ AIDAGYRHID A +Y E +
Sbjct: 1 MATFVELSTKAKMPIVGLGTWKSPLGK------VKEAVKVAIDAGYRHIDCAYVYQNEHE 54
Query: 298 VGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLIHWPI 477
VG AI++KI E VKREDLF+ +KLW T ++ V A K+LK+L L Y+++YLIHWP
Sbjct: 55 VGEAIQEKIQEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQ 114
Query: 478 ALHE-----------NASISQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLEXLKSXG 624
NA + +++ W+AM +++++GL K++GVSNF+ Q+E L +
Sbjct: 115 GFKSGDDLFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKP 174
Query: 625 GV--TPSVLQVEINLNLQRSALLDYCKAQGIXVVAYTPLRXSVQP 753
G+ P QVE + L + L+ YC ++GI V AY+PL +P
Sbjct: 175 GLKYKPVTNQVECHPYLTQEKLIQYCHSKGITVTAYSPLGSPDRP 219
>CR541801-1|CAG46600.1| 316|Homo sapiens AKR1B10 protein.
Length = 316
Score = 158 bits (384), Expect = 2e-38
Identities = 87/225 (38%), Positives = 134/225 (59%), Gaps = 13/225 (5%)
Frame = +1
Query: 118 LAPVLKLNNGKEIPGFGIGTWLGTNSNELKGD*VQKSVEWAIDAGYRHIDTAAIYSTEDQ 297
+A ++L+ ++P G+GTW V+++V+ AIDAGYRHID A +Y E +
Sbjct: 1 MATFVELSTKAKMPIVGLGTWKSPLGK------VKEAVKVAIDAGYRHIDCAYVYQNEHE 54
Query: 298 VGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLIHWPI 477
VG AI++KI E VKREDLF+ +KLW T ++ V A K+LK+L L Y+++YLIHWP
Sbjct: 55 VGEAIQEKIQEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQ 114
Query: 478 ALHE-----------NASISQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLEXLKSXG 624
NA + +++ W+AM +++++GL K++GVSNF+ Q+E L +
Sbjct: 115 GFKSGDDLFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKP 174
Query: 625 GV--TPSVLQVEINLNLQRSALLDYCKAQGIXVVAYTPLRXSVQP 753
G+ P QVE + L + L+ YC ++GI V AY+PL +P
Sbjct: 175 GLKYKPVTNQVECHPYLTQEKLIQYCHSKGITVTAYSPLGSPDRP 219
>BT006794-1|AAP35440.1| 316|Homo sapiens aldo-keto reductase family
1, member B10 (aldose reductase) protein.
Length = 316
Score = 158 bits (384), Expect = 2e-38
Identities = 87/225 (38%), Positives = 134/225 (59%), Gaps = 13/225 (5%)
Frame = +1
Query: 118 LAPVLKLNNGKEIPGFGIGTWLGTNSNELKGD*VQKSVEWAIDAGYRHIDTAAIYSTEDQ 297
+A ++L+ ++P G+GTW V+++V+ AIDAGYRHID A +Y E +
Sbjct: 1 MATFVELSTKAKMPIVGLGTWKSPLGK------VKEAVKVAIDAGYRHIDCAYVYQNEHE 54
Query: 298 VGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLIHWPI 477
VG AI++KI E VKREDLF+ +KLW T ++ V A K+LK+L L Y+++YLIHWP
Sbjct: 55 VGEAIQEKIQEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQ 114
Query: 478 ALHE-----------NASISQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLEXLKSXG 624
NA + +++ W+AM +++++GL K++GVSNF+ Q+E L +
Sbjct: 115 GFKSGDDLFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKP 174
Query: 625 GV--TPSVLQVEINLNLQRSALLDYCKAQGIXVVAYTPLRXSVQP 753
G+ P QVE + L + L+ YC ++GI V AY+PL +P
Sbjct: 175 GLKYKPVTNQVECHPYLTQEKLIQYCHSKGITVTAYSPLGSPDRP 219
>BC008837-1|AAH08837.1| 316|Homo sapiens aldo-keto reductase family
1, member B10 (aldose reductase) protein.
Length = 316
Score = 158 bits (384), Expect = 2e-38
Identities = 87/225 (38%), Positives = 134/225 (59%), Gaps = 13/225 (5%)
Frame = +1
Query: 118 LAPVLKLNNGKEIPGFGIGTWLGTNSNELKGD*VQKSVEWAIDAGYRHIDTAAIYSTEDQ 297
+A ++L+ ++P G+GTW V+++V+ AIDAGYRHID A +Y E +
Sbjct: 1 MATFVELSTKAKMPIVGLGTWKSPLGK------VKEAVKVAIDAGYRHIDCAYVYQNEHE 54
Query: 298 VGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLIHWPI 477
VG AI++KI E VKREDLF+ +KLW T ++ V A K+LK+L L Y+++YLIHWP
Sbjct: 55 VGEAIQEKIQEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQ 114
Query: 478 ALHE-----------NASISQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLEXLKSXG 624
NA + +++ W+AM +++++GL K++GVSNF+ Q+E L +
Sbjct: 115 GFKSGDDLFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKP 174
Query: 625 GV--TPSVLQVEINLNLQRSALLDYCKAQGIXVVAYTPLRXSVQP 753
G+ P QVE + L + L+ YC ++GI V AY+PL +P
Sbjct: 175 GLKYKPVTNQVECHPYLTQEKLIQYCHSKGITVTAYSPLGSPDRP 219
>AF052577-1|AAC36465.1| 316|Homo sapiens aldo-keto reductase
protein.
Length = 316
Score = 158 bits (384), Expect = 2e-38
Identities = 87/225 (38%), Positives = 134/225 (59%), Gaps = 13/225 (5%)
Frame = +1
Query: 118 LAPVLKLNNGKEIPGFGIGTWLGTNSNELKGD*VQKSVEWAIDAGYRHIDTAAIYSTEDQ 297
+A ++L+ ++P G+GTW V+++V+ AIDAGYRHID A +Y E +
Sbjct: 1 MATFVELSTKAKMPIVGLGTWKSPLGK------VKEAVKVAIDAGYRHIDCAYVYQNEHE 54
Query: 298 VGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLIHWPI 477
VG AI++KI E VKREDLF+ +KLW T ++ V A K+LK+L L Y+++YLIHWP
Sbjct: 55 VGEAIQEKIQEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQ 114
Query: 478 ALHE-----------NASISQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLEXLKSXG 624
NA + +++ W+AM +++++GL K++GVSNF+ Q+E L +
Sbjct: 115 GFKSGDDLFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKP 174
Query: 625 GV--TPSVLQVEINLNLQRSALLDYCKAQGIXVVAYTPLRXSVQP 753
G+ P QVE + L + L+ YC ++GI V AY+PL +P
Sbjct: 175 GLKYKPVTNQVECHPYLTQEKLIQYCHSKGITVTAYSPLGSPDRP 219
>M33375-1|AAA35658.1| 308|Homo sapiens protein ( Human chlordecone
reductase mRNA, complete cds. ).
Length = 308
Score = 158 bits (383), Expect = 3e-38
Identities = 91/207 (43%), Positives = 128/207 (61%), Gaps = 13/207 (6%)
Frame = +1
Query: 154 IPGFGIGTWLGTNSNELKGD*VQKSVEWAIDAGYRHIDTAAIYSTEDQVGRAIKKKIAEG 333
+P G GT+ E+ + + + AI+AG+RHID+A +Y+ E+QVG AI+ KIA+G
Sbjct: 1 MPVLGFGTYAPP---EVPRNRAVEVTKLAIEAGFRHIDSAYLYNNEEQVGLAIRSKIADG 57
Query: 334 VVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLIHWPIAL---------H 486
VKRED+F T+KLW T + + V PAL SLK L LDYV+LYL+H+P+AL
Sbjct: 58 SVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALKPGETPLPKD 117
Query: 487 ENASI--SQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLEXLKSXGGV--TPSVLQVE 654
EN + D TW+ M + GL KSIGVSNFN +QLE + + G+ P QVE
Sbjct: 118 ENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILNKPGLKYKPVCNQVE 177
Query: 655 INLNLQRSALLDYCKAQGIXVVAYTPL 735
+ L +S LLD+CK++ I +VA++ L
Sbjct: 178 CHPYLNQSKLLDFCKSKDIVLVAHSAL 204
>Z28339-1|CAA82193.1| 326|Homo sapiens delta 4-3-oxosteroid 5
beta-reductase protein.
Length = 326
Score = 156 bits (378), Expect = 1e-37
Identities = 96/228 (42%), Positives = 130/228 (57%), Gaps = 13/228 (5%)
Frame = +1
Query: 130 LKLNNGKEIPGFGIGTWLGTNSNELKGD*VQKSVEWAIDAGYRHIDTAAIYSTEDQVGRA 309
+ L++G IP G+GT+ S KG SV+ AID GYRHID A IY E +VG A
Sbjct: 10 IPLSDGNSIPIIGLGTYSEPKSTP-KGA-CATSVKVAIDTGYRHIDGAYIYQNEHEVGEA 67
Query: 310 IKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLIHWPIAL-- 483
I++KIAEG V+RED+F KLW TNH E V P L ++L+ L LDYV+LY+I P+A
Sbjct: 68 IREKIAEGKVRREDIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLYIIEVPMAFKP 127
Query: 484 -------HENAS--ISQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLEXLKSXGGV-- 630
EN +++ TW+AM + GL KS+GVSNFN +QLE + + G+
Sbjct: 128 GDEIYPRDENGKWLYHKSNLCATWEAMEACKDAGLVKSLGVSNFNRRQLELILNKPGLKH 187
Query: 631 TPSVLQVEINLNLQRSALLDYCKAQGIXVVAYTPLRXSVQPPAVGSSA 774
P QVE + + LL +C+ I + AY+PL S P V S+
Sbjct: 188 KPVSNQVECHPYFTQPKLLKFCQQHDIVITAYSPLGTSRNPIWVNVSS 235
>BC130627-1|AAI30628.1| 326|Homo sapiens aldo-keto reductase family
1, member D1 (delta 4-3-ketosteroid-5-beta-reductase
protein.
Length = 326
Score = 156 bits (378), Expect = 1e-37
Identities = 96/228 (42%), Positives = 130/228 (57%), Gaps = 13/228 (5%)
Frame = +1
Query: 130 LKLNNGKEIPGFGIGTWLGTNSNELKGD*VQKSVEWAIDAGYRHIDTAAIYSTEDQVGRA 309
+ L++G IP G+GT+ S KG SV+ AID GYRHID A IY E +VG A
Sbjct: 10 IPLSDGNSIPIIGLGTYSEPKSTP-KGA-CATSVKVAIDTGYRHIDGAYIYQNEHEVGEA 67
Query: 310 IKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLIHWPIAL-- 483
I++KIAEG V+RED+F KLW TNH E V P L ++L+ L LDYV+LY+I P+A
Sbjct: 68 IREKIAEGKVRREDIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLYIIEVPMAFKP 127
Query: 484 -------HENAS--ISQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLEXLKSXGGV-- 630
EN +++ TW+AM + GL KS+GVSNFN +QLE + + G+
Sbjct: 128 GDEIYPRDENGKWLYHKSNLCATWEAMEACKDAGLVKSLGVSNFNRRQLELILNKPGLKH 187
Query: 631 TPSVLQVEINLNLQRSALLDYCKAQGIXVVAYTPLRXSVQPPAVGSSA 774
P QVE + + LL +C+ I + AY+PL S P V S+
Sbjct: 188 KPVSNQVECHPYFTQPKLLKFCQQHDIVITAYSPLGTSRNPIWVNVSS 235
>BC130625-1|AAI30626.1| 326|Homo sapiens aldo-keto reductase family
1, member D1 (delta 4-3-ketosteroid-5-beta-reductase
protein.
Length = 326
Score = 156 bits (378), Expect = 1e-37
Identities = 96/228 (42%), Positives = 130/228 (57%), Gaps = 13/228 (5%)
Frame = +1
Query: 130 LKLNNGKEIPGFGIGTWLGTNSNELKGD*VQKSVEWAIDAGYRHIDTAAIYSTEDQVGRA 309
+ L++G IP G+GT+ S KG SV+ AID GYRHID A IY E +VG A
Sbjct: 10 IPLSDGNSIPIIGLGTYSEPKSTP-KGA-CATSVKVAIDTGYRHIDGAYIYQNEHEVGEA 67
Query: 310 IKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLIHWPIAL-- 483
I++KIAEG V+RED+F KLW TNH E V P L ++L+ L LDYV+LY+I P+A
Sbjct: 68 IREKIAEGKVRREDIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLYIIEVPMAFKP 127
Query: 484 -------HENAS--ISQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLEXLKSXGGV-- 630
EN +++ TW+AM + GL KS+GVSNFN +QLE + + G+
Sbjct: 128 GDEIYPRDENGKWLYHKSNLCATWEAMEACKDAGLVKSLGVSNFNRRQLELILNKPGLKH 187
Query: 631 TPSVLQVEINLNLQRSALLDYCKAQGIXVVAYTPLRXSVQPPAVGSSA 774
P QVE + + LL +C+ I + AY+PL S P V S+
Sbjct: 188 KPVSNQVECHPYFTQPKLLKFCQQHDIVITAYSPLGTSRNPIWVNVSS 235
>AF283659-1|AAG39381.1| 326|Homo sapiens 5-beta steroid reductase
protein.
Length = 326
Score = 156 bits (378), Expect = 1e-37
Identities = 96/228 (42%), Positives = 130/228 (57%), Gaps = 13/228 (5%)
Frame = +1
Query: 130 LKLNNGKEIPGFGIGTWLGTNSNELKGD*VQKSVEWAIDAGYRHIDTAAIYSTEDQVGRA 309
+ L++G IP G+GT+ S KG SV+ AID GYRHID A IY E +VG A
Sbjct: 10 IPLSDGNSIPIIGLGTYSEPKSTP-KGA-CATSVKVAIDTGYRHIDGAYIYQNEHEVGEA 67
Query: 310 IKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLIHWPIAL-- 483
I++KIAEG V+RED+F KLW TNH E V P L ++L+ L LDYV+LY+I P+A
Sbjct: 68 IREKIAEGKVRREDIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLYIIEVPMAFKP 127
Query: 484 -------HENAS--ISQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLEXLKSXGGV-- 630
EN +++ TW+AM + GL KS+GVSNFN +QLE + + G+
Sbjct: 128 GDEIYPRDENGKWLYHKSNLCATWEAMEACKDAGLVKSLGVSNFNRRQLELILNKPGLKH 187
Query: 631 TPSVLQVEINLNLQRSALLDYCKAQGIXVVAYTPLRXSVQPPAVGSSA 774
P QVE + + LL +C+ I + AY+PL S P V S+
Sbjct: 188 KPVSNQVECHPYFTQPKLLKFCQQHDIVITAYSPLGTSRNPIWVNVSS 235
>AF524864-1|AAO13380.1| 316|Homo sapiens aldo-ketoreductase
protein.
Length = 316
Score = 155 bits (377), Expect = 2e-37
Identities = 86/225 (38%), Positives = 133/225 (59%), Gaps = 13/225 (5%)
Frame = +1
Query: 118 LAPVLKLNNGKEIPGFGIGTWLGTNSNELKGD*VQKSVEWAIDAGYRHIDTAAIYSTEDQ 297
+A ++L+ ++P G+GTW V+++V+ AIDAGYRHID A +Y E +
Sbjct: 1 MATFVELSTKAKMPIVGLGTWKSPLGK------VKEAVKVAIDAGYRHIDCAYVYQNEHE 54
Query: 298 VGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLIHWPI 477
VG AI++KI E VKREDLF+ +KLW T ++ V A K+LK+ L Y+++YLIHWP
Sbjct: 55 VGEAIQEKIQEKAVKREDLFIASKLWPTFFERPLVRKAFEKTLKDPKLSYLDVYLIHWPQ 114
Query: 478 ALHE-----------NASISQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLEXLKSXG 624
NA + +++ W+AM +++++GL K++GVSNF+ Q+E L +
Sbjct: 115 GFKSGDDLFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKP 174
Query: 625 GV--TPSVLQVEINLNLQRSALLDYCKAQGIXVVAYTPLRXSVQP 753
G+ P QVE + L + L+ YC ++GI V AY+PL +P
Sbjct: 175 GLKYKPVTNQVECHPYLTQEKLIQYCHSKGITVTAYSPLGSPDRP 219
>AL713867-3|CAI16410.1| 247|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 247
Score = 136 bits (329), Expect(2) = 8e-32
Identities = 77/169 (45%), Positives = 105/169 (62%), Gaps = 13/169 (7%)
Frame = +1
Query: 295 QVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLIHWP 474
+VG AI+ KIA+G VKRED+F T+KLW +H+ E V PAL +SLKNL LDYV+LYLIH+P
Sbjct: 26 EVGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFP 85
Query: 475 IAL---------HENASI--SQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLEXLKSX 621
+++ EN I D TW+A+ + GL KSIGVSNFN +QLE + +
Sbjct: 86 VSVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNK 145
Query: 622 GGV--TPSVLQVEINLNLQRSALLDYCKAQGIXVVAYTPLRXSVQPPAV 762
G+ P QVE + + LLD+CK++ I +VAY+ L + P V
Sbjct: 146 PGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWV 194
Score = 21.4 bits (43), Expect(2) = 8e-32
Identities = 8/17 (47%), Positives = 12/17 (70%)
Frame = +1
Query: 130 LKLNNGKEIPGFGIGTW 180
+KLN+G +P G GT+
Sbjct: 6 VKLNDGHFMPVLGFGTY 22
>BC002862-1|AAH02862.1| 307|Homo sapiens AKR1CL2 protein protein.
Length = 307
Score = 124 bits (299), Expect = 4e-28
Identities = 86/232 (37%), Positives = 125/232 (53%), Gaps = 32/232 (13%)
Frame = +1
Query: 151 EIPGFGIGTWLGTNSNELKGD*VQKSVEWAIDAGYRHIDTAAIYSTEDQVGRAIKKKIAE 330
+IP G+ +W + V ++V+ AIDAGYRH D A Y E +VG I+ KI E
Sbjct: 3 DIPAVGLSSWKASPGK------VTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKE 56
Query: 331 GVVKREDLFVTTKLWNTNHKKEAVLPALR---KSLK--NLDLDYVNL------------- 456
G V+REDLF+ TKLW T HKK V A R K+LK LDL ++
Sbjct: 57 GAVRREDLFIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPMGFKPPHPEWIM 116
Query: 457 ------YLIHWP----IALHENASI--SQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQ 600
+ + P + L E+ + S TD+++TW+AM D++ GL K+IGVSNFN +Q
Sbjct: 117 SCSELSFCLSHPRVQDLPLDESNMVIPSDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQ 176
Query: 601 LEXLKSXGGV--TPSVLQVEINLNLQRSALLDYCKAQGIXVVAYTPLRXSVQ 750
LE L + G+ P Q+E + L + L+ +C+++ + V AY PL S +
Sbjct: 177 LERLLNKPGLRFKPLTNQIECHPYLTQKNLISFCQSRDVSVTAYRPLGGSCE 228
>AF263242-1|AAK58523.1| 320|Homo sapiens aldo-keto reductase
loopADR protein.
Length = 320
Score = 124 bits (299), Expect = 4e-28
Identities = 86/232 (37%), Positives = 125/232 (53%), Gaps = 32/232 (13%)
Frame = +1
Query: 151 EIPGFGIGTWLGTNSNELKGD*VQKSVEWAIDAGYRHIDTAAIYSTEDQVGRAIKKKIAE 330
+IP G+ +W + V ++V+ AIDAGYRH D A Y E +VG I+ KI E
Sbjct: 3 DIPAVGLSSWKASPGK------VTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKE 56
Query: 331 GVVKREDLFVTTKLWNTNHKKEAVLPALR---KSLK--NLDLDYVNL------------- 456
G V+REDLF+ TKLW T HKK V A R K+LK LDL ++
Sbjct: 57 GAVRREDLFIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPMGFKPPHPEWIM 116
Query: 457 ------YLIHWP----IALHENASI--SQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQ 600
+ + P + L E+ + S TD+++TW+AM D++ GL K+IGVSNFN +Q
Sbjct: 117 SCSELSFCLSHPRVQDLPLDESNMVIPSDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQ 176
Query: 601 LEXLKSXGGV--TPSVLQVEINLNLQRSALLDYCKAQGIXVVAYTPLRXSVQ 750
LE L + G+ P Q+E + L + L+ +C+++ + V AY PL S +
Sbjct: 177 LERLLNKPGLRFKPLTNQIECHPYLTQKNLISFCQSRDVSVTAYRPLGGSCE 228
>AB055603-1|BAC54568.1| 307|Homo sapiens aldo-keto reductase
related protein 4 protein.
Length = 307
Score = 124 bits (299), Expect = 4e-28
Identities = 86/232 (37%), Positives = 125/232 (53%), Gaps = 32/232 (13%)
Frame = +1
Query: 151 EIPGFGIGTWLGTNSNELKGD*VQKSVEWAIDAGYRHIDTAAIYSTEDQVGRAIKKKIAE 330
+IP G+ +W + V ++V+ AIDAGYRH D A Y E +VG I+ KI E
Sbjct: 3 DIPAVGLSSWKASPGK------VTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKE 56
Query: 331 GVVKREDLFVTTKLWNTNHKKEAVLPALR---KSLK--NLDLDYVNL------------- 456
G V+REDLF+ TKLW T HKK V A R K+LK LDL ++
Sbjct: 57 GAVRREDLFIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPMGFKPPHPEWIM 116
Query: 457 ------YLIHWP----IALHENASI--SQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQ 600
+ + P + L E+ + S TD+++TW+AM D++ GL K+IGVSNFN +Q
Sbjct: 117 SCSELSFCLSHPRVQDLPLDESNMVIPSDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQ 176
Query: 601 LEXLKSXGGV--TPSVLQVEINLNLQRSALLDYCKAQGIXVVAYTPLRXSVQ 750
LE L + G+ P Q+E + L + L+ +C+++ + V AY PL S +
Sbjct: 177 LERLLNKPGLRFKPLTNQIECHPYLTQKNLISFCQSRDVSVTAYRPLGGSCE 228
>AL355480-2|CAI22458.1| 147|Homo sapiens aldo-keto reductase family
1, member A1 (aldehydela) protein.
Length = 147
Score = 122 bits (294), Expect = 2e-27
Identities = 65/151 (43%), Positives = 92/151 (60%), Gaps = 12/151 (7%)
Frame = +1
Query: 121 APVLKLNNGKEIPGFGIGTWLGTNSNELKGD*VQKSVEWAIDAGYRHIDTAAIYSTEDQV 300
A + L+ G+++P G+GTW V+ +V++A+ GYRHID AAIY E ++
Sbjct: 3 ASCVLLHTGQKMPLIGLGTWKSEPGQ------VKAAVKYALSVGYRHIDCAAIYGNEPEI 56
Query: 301 GRAIKKKIAEG-VVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLIHWPI 477
G A+K+ + G V RE+LFVT+KLWNT H E V PALRK+L +L L+Y++LYL+HWP
Sbjct: 57 GEALKEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPY 116
Query: 478 ALH-------ENAS----ISQTDYVETWQAM 537
A +NA T Y ETW+A+
Sbjct: 117 AFERGDNPFPKNADGTICYDSTHYKETWKAL 147
>AL391427-2|CAI14727.1| 302|Homo sapiens aldo-keto reductase family
1, member C-like 1 protein.
Length = 302
Score = 116 bits (278), Expect = 2e-25
Identities = 73/211 (34%), Positives = 122/211 (57%), Gaps = 3/211 (1%)
Frame = +1
Query: 130 LKLNNGKEIPGFGIGTWLGTNSNELKGD*VQKSVEWAIDAGYRHIDTAAIYSTEDQVGRA 309
++LN+G +P G GT+ ++ + + ++ + AID G+RHID+A +Y E++VG+A
Sbjct: 11 VRLNDGPFMPVLGFGTYAPDHTPKSQA---AEATKVAIDVGFRHIDSAYLYQNEEEVGQA 67
Query: 310 IKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLIHWPIALHE 489
I +KIA+G VKRE++F T KLW T + E V PAL +SLK L DYV+L++IH P A+ +
Sbjct: 68 IWEKIADGTVKREEIFYTIKLWATFFRAELVHPALERSLKKLGPDYVDLFIIHVPFAMKQ 127
Query: 490 NASISQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLEXLKSXGGV--TPSVLQ-VEIN 660
D + + +++ + + +LE + + G+ P+ Q VE +
Sbjct: 128 PGK---------ELLPKDASGEIILETVELC--DTWELELILNKPGLRYKPTCNQVVECH 176
Query: 661 LNLQRSALLDYCKAQGIXVVAYTPLRXSVQP 753
L +S LL++CK++ I +VAY+ L P
Sbjct: 177 PYLNQSKLLEFCKSKDIVLVAYSALGSQRDP 207
>AL355303-1|CAI14201.1| 302|Homo sapiens aldo-keto reductase family
1, member C-like 1 protein.
Length = 302
Score = 116 bits (278), Expect = 2e-25
Identities = 73/211 (34%), Positives = 122/211 (57%), Gaps = 3/211 (1%)
Frame = +1
Query: 130 LKLNNGKEIPGFGIGTWLGTNSNELKGD*VQKSVEWAIDAGYRHIDTAAIYSTEDQVGRA 309
++LN+G +P G GT+ ++ + + ++ + AID G+RHID+A +Y E++VG+A
Sbjct: 11 VRLNDGPFMPVLGFGTYAPDHTPKSQA---AEATKVAIDVGFRHIDSAYLYQNEEEVGQA 67
Query: 310 IKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLIHWPIALHE 489
I +KIA+G VKRE++F T KLW T + E V PAL +SLK L DYV+L++IH P A+ +
Sbjct: 68 IWEKIADGTVKREEIFYTIKLWATFFRAELVHPALERSLKKLGPDYVDLFIIHVPFAMKQ 127
Query: 490 NASISQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLEXLKSXGGV--TPSVLQ-VEIN 660
D + + +++ + + +LE + + G+ P+ Q VE +
Sbjct: 128 PGK---------ELLPKDASGEIILETVELC--DTWELELILNKPGLRYKPTCNQVVECH 176
Query: 661 LNLQRSALLDYCKAQGIXVVAYTPLRXSVQP 753
L +S LL++CK++ I +VAY+ L P
Sbjct: 177 PYLNQSKLLEFCKSKDIVLVAYSALGSQRDP 207
>AB040822-1|BAC54567.1| 222|Homo sapiens aldo-keto reductase
related protein 3 protein.
Length = 222
Score = 113 bits (271), Expect = 1e-24
Identities = 56/109 (51%), Positives = 71/109 (65%)
Frame = +1
Query: 151 EIPGFGIGTWLGTNSNELKGD*VQKSVEWAIDAGYRHIDTAAIYSTEDQVGRAIKKKIAE 330
+IP G+ +W + V ++V+ AIDAGYRH D A Y E +VG I+ KI E
Sbjct: 3 DIPAVGLSSWKASPGK------VTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKE 56
Query: 331 GVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLIHWPI 477
G V+REDLF+ TKLW T HKK V A RKSLK L L+Y++LYLIHWP+
Sbjct: 57 GAVRREDLFIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPM 105
>AB040821-1|BAC54566.1| 263|Homo sapiens aldo-keto reductase
related protein 2 protein.
Length = 263
Score = 113 bits (271), Expect = 1e-24
Identities = 56/109 (51%), Positives = 71/109 (65%)
Frame = +1
Query: 151 EIPGFGIGTWLGTNSNELKGD*VQKSVEWAIDAGYRHIDTAAIYSTEDQVGRAIKKKIAE 330
+IP G+ +W + V ++V+ AIDAGYRH D A Y E +VG I+ KI E
Sbjct: 3 DIPAVGLSSWKASPGK------VTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKE 56
Query: 331 GVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLIHWPI 477
G V+REDLF+ TKLW T HKK V A RKSLK L L+Y++LYLIHWP+
Sbjct: 57 GAVRREDLFIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPM 105
>AB040820-1|BAC54565.1| 250|Homo sapiens aldo-keto reductase
related protein 1 protein.
Length = 250
Score = 113 bits (271), Expect = 1e-24
Identities = 56/109 (51%), Positives = 71/109 (65%)
Frame = +1
Query: 151 EIPGFGIGTWLGTNSNELKGD*VQKSVEWAIDAGYRHIDTAAIYSTEDQVGRAIKKKIAE 330
+IP G+ +W + V ++V+ AIDAGYRH D A Y E +VG I+ KI E
Sbjct: 3 DIPAVGLSSWKASPGK------VTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKE 56
Query: 331 GVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLIHWPI 477
G V+REDLF+ TKLW T HKK V A RKSLK L L+Y++LYLIHWP+
Sbjct: 57 GAVRREDLFIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPM 105
>AB037902-1|BAA92887.1| 130|Homo sapiens truncated aldo-keto
reductase protein.
Length = 130
Score = 112 bits (269), Expect = 2e-24
Identities = 56/123 (45%), Positives = 81/123 (65%)
Frame = +1
Query: 130 LKLNNGKEIPGFGIGTWLGTNSNELKGD*VQKSVEWAIDAGYRHIDTAAIYSTEDQVGRA 309
+KLN+GK +P G GT + + ++ V+++V+ AID GYRHID+A + E+ +G+A
Sbjct: 9 VKLNDGKFMPILGFGTSV---ARKVAMSNVEEAVQVAIDVGYRHIDSAYTHLNEEGIGQA 65
Query: 310 IKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLIHWPIALHE 489
I+KKIA G VKR+D+F TTK+W T + E V L SLK L L Y++LYL H+P+ L
Sbjct: 66 IRKKIANGTVKRKDIFYTTKVWGTFSRPELVQRGLEMSLKKLQLSYMDLYLFHFPVPLQP 125
Query: 490 NAS 498
S
Sbjct: 126 GRS 128
>BC101205-1|AAI01206.1| 129|Homo sapiens aldo-keto reductase family
1, member C-like 1 protein.
Length = 129
Score = 109 bits (261), Expect = 2e-23
Identities = 53/118 (44%), Positives = 81/118 (68%)
Frame = +1
Query: 130 LKLNNGKEIPGFGIGTWLGTNSNELKGD*VQKSVEWAIDAGYRHIDTAAIYSTEDQVGRA 309
++LN+G +P G GT+ ++ + + ++ + AID G+RHID+A +Y E++VG+A
Sbjct: 11 VRLNDGPFMPVLGFGTYAPDHTPKSQA---AEATKVAIDVGFRHIDSAYLYQNEEEVGQA 67
Query: 310 IKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLIHWPIAL 483
I +KIA+G VKRE++F T KLW T + E V PAL +SLK L DYV+L++IH P A+
Sbjct: 68 IWEKIADGTVKREEIFYTIKLWATFFRAELVHPALERSLKKLGPDYVDLFIIHVPFAM 125
>BC101204-1|AAI01205.1| 129|Homo sapiens aldo-keto reductase family
1, member C-like 1 protein.
Length = 129
Score = 109 bits (261), Expect = 2e-23
Identities = 53/118 (44%), Positives = 81/118 (68%)
Frame = +1
Query: 130 LKLNNGKEIPGFGIGTWLGTNSNELKGD*VQKSVEWAIDAGYRHIDTAAIYSTEDQVGRA 309
++LN+G +P G GT+ ++ + + ++ + AID G+RHID+A +Y E++VG+A
Sbjct: 11 VRLNDGPFMPVLGFGTYAPDHTPKSQA---AEATKVAIDVGFRHIDSAYLYQNEEEVGQA 67
Query: 310 IKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLIHWPIAL 483
I +KIA+G VKRE++F T KLW T + E V PAL +SLK L DYV+L++IH P A+
Sbjct: 68 IWEKIADGTVKREEIFYTIKLWATFFRAELVHPALERSLKKLGPDYVDLFIIHVPFAM 125
>AK131335-1|BAD18494.1| 129|Homo sapiens protein ( Homo sapiens
cDNA FLJ16347 fis, clone TESTI2036288, moderately
similar to PROSTAGLANDIN-F SYNTHASE 1 (EC 1.1.1.188). ).
Length = 129
Score = 109 bits (261), Expect = 2e-23
Identities = 53/118 (44%), Positives = 81/118 (68%)
Frame = +1
Query: 130 LKLNNGKEIPGFGIGTWLGTNSNELKGD*VQKSVEWAIDAGYRHIDTAAIYSTEDQVGRA 309
++LN+G +P G GT+ ++ + + ++ + AID G+RHID+A +Y E++VG+A
Sbjct: 11 VRLNDGPFMPVLGFGTYAPDHTPKSQA---AEATKVAIDVGFRHIDSAYLYQNEEEVGQA 67
Query: 310 IKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLIHWPIAL 483
I +KIA+G VKRE++F T KLW T + E V PAL +SLK L DYV+L++IH P A+
Sbjct: 68 IWEKIADGTVKREEIFYTIKLWATFFRAELVHPALERSLKKLGPDYVDLFIIHVPFAM 125
>AK058142-1|BAB71682.1| 146|Homo sapiens protein ( Homo sapiens
cDNA FLJ25413 fis, clone TST03402, highly similar to
3-OXO-5-BETA-STEROID 4-DEHYDROGENASE (EC 1.3.99.6). ).
Length = 146
Score = 58.4 bits (135), Expect = 3e-08
Identities = 32/79 (40%), Positives = 45/79 (56%), Gaps = 2/79 (2%)
Frame = +1
Query: 523 TWQAMTDVLNQGLTKSIGVSNFNIQQLEXLKSXGGV--TPSVLQVEINLNLQRSALLDYC 696
TW+AM + GL KS+GVSNFN +QLE + + G+ P QVE + + LL +C
Sbjct: 28 TWEAMEACKDAGLVKSLGVSNFNRRQLELILNKPGLKHKPVSNQVECHPYFTQPKLLKFC 87
Query: 697 KAQGIXVVAYTPLRXSVQP 753
+ I + AY+PL S P
Sbjct: 88 QQHDIVITAYSPLGTSRNP 106
>U33429-1|AAC50955.1| 367|Homo sapiens K+ channel beta 2 subunit
protein.
Length = 367
Score = 54.4 bits (125), Expect = 5e-07
Identities = 46/164 (28%), Positives = 78/164 (47%), Gaps = 10/164 (6%)
Frame = +1
Query: 142 NGKEIPGFGIGTWLGTNSNELKGD*VQKSVEWAIDAGYRHIDTAAIYST---EDQVGRAI 312
+G + G+GTW+ T ++ + ++ + A D G DTA +Y+ E +G I
Sbjct: 45 SGLRVSCLGLGTWV-TFGGQITDEMAEQLMTLAYDNGINLFDTAEVYAAGKAEVVLGNII 103
Query: 313 KKKIAEGVVKREDLFVTTKL-WNTNHKKEA------VLPALRKSLKNLDLDYVNLYLIHW 471
KKK +R L +TTK+ W + E ++ L+ SL+ L L+YV++ +
Sbjct: 104 KKK----GWRRSSLVITTKIFWGGKAETERGLSRKHIIEGLKASLERLQLEYVDVVFANR 159
Query: 472 PIALHENASISQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQL 603
P T ET +AMT V+NQG+ G S ++ ++
Sbjct: 160 PDP--------NTPMEETVRAMTHVINQGMAMYWGTSRWSSMEI 195
>CR542287-1|CAG47082.1| 353|Homo sapiens KCNAB2 protein.
Length = 353
Score = 54.4 bits (125), Expect = 5e-07
Identities = 46/164 (28%), Positives = 78/164 (47%), Gaps = 10/164 (6%)
Frame = +1
Query: 142 NGKEIPGFGIGTWLGTNSNELKGD*VQKSVEWAIDAGYRHIDTAAIYST---EDQVGRAI 312
+G + G+GTW+ T ++ + ++ + A D G DTA +Y+ E +G I
Sbjct: 31 SGLRVSCLGLGTWV-TFGGQITDEMAEQLMTLAYDNGINLFDTAEVYAAGKAEVVLGNII 89
Query: 313 KKKIAEGVVKREDLFVTTKL-WNTNHKKEA------VLPALRKSLKNLDLDYVNLYLIHW 471
KKK +R L +TTK+ W + E ++ L+ SL+ L L+YV++ +
Sbjct: 90 KKK----GWRRSSLVITTKIFWGGKAETERGLSRKHIIEGLKASLERLQLEYVDVVFANR 145
Query: 472 PIALHENASISQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQL 603
P T ET +AMT V+NQG+ G S ++ ++
Sbjct: 146 PDP--------NTPMEETVRAMTHVINQGMAMYWGTSRWSSMEI 181
>BC130413-1|AAI30414.1| 367|Homo sapiens potassium voltage-gated
channel, shaker-related subfamily, beta member 2
protein.
Length = 367
Score = 54.4 bits (125), Expect = 5e-07
Identities = 46/164 (28%), Positives = 78/164 (47%), Gaps = 10/164 (6%)
Frame = +1
Query: 142 NGKEIPGFGIGTWLGTNSNELKGD*VQKSVEWAIDAGYRHIDTAAIYST---EDQVGRAI 312
+G + G+GTW+ T ++ + ++ + A D G DTA +Y+ E +G I
Sbjct: 45 SGLRVSCLGLGTWV-TFGGQITDEMAEQLMTLAYDNGINLFDTAEVYAAGKAEVVLGNII 103
Query: 313 KKKIAEGVVKREDLFVTTKL-WNTNHKKEA------VLPALRKSLKNLDLDYVNLYLIHW 471
KKK +R L +TTK+ W + E ++ L+ SL+ L L+YV++ +
Sbjct: 104 KKK----GWRRSSLVITTKIFWGGKAETERGLSRKHIIEGLKASLERLQLEYVDVVFANR 159
Query: 472 PIALHENASISQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQL 603
P T ET +AMT V+NQG+ G S ++ ++
Sbjct: 160 PDP--------NTPMEETVRAMTHVINQGMAMYWGTSRWSSMEI 195
>BC126424-1|AAI26425.1| 367|Homo sapiens potassium voltage-gated
channel, shaker-related subfamily, beta member 2
protein.
Length = 367
Score = 54.4 bits (125), Expect = 5e-07
Identities = 46/164 (28%), Positives = 78/164 (47%), Gaps = 10/164 (6%)
Frame = +1
Query: 142 NGKEIPGFGIGTWLGTNSNELKGD*VQKSVEWAIDAGYRHIDTAAIYST---EDQVGRAI 312
+G + G+GTW+ T ++ + ++ + A D G DTA +Y+ E +G I
Sbjct: 45 SGLRVSCLGLGTWV-TFGGQITDEMAEQLMTLAYDNGINLFDTAEVYAAGKAEVVLGNII 103
Query: 313 KKKIAEGVVKREDLFVTTKL-WNTNHKKEA------VLPALRKSLKNLDLDYVNLYLIHW 471
KKK +R L +TTK+ W + E ++ L+ SL+ L L+YV++ +
Sbjct: 104 KKK----GWRRSSLVITTKIFWGGKAETERGLSRKHIIEGLKASLERLQLEYVDVVFANR 159
Query: 472 PIALHENASISQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQL 603
P T ET +AMT V+NQG+ G S ++ ++
Sbjct: 160 PDP--------NTPMEETVRAMTHVINQGMAMYWGTSRWSSMEI 195
>BC110351-1|AAI10352.1| 395|Homo sapiens KCNAB2 protein protein.
Length = 395
Score = 54.4 bits (125), Expect = 5e-07
Identities = 46/164 (28%), Positives = 78/164 (47%), Gaps = 10/164 (6%)
Frame = +1
Query: 142 NGKEIPGFGIGTWLGTNSNELKGD*VQKSVEWAIDAGYRHIDTAAIYST---EDQVGRAI 312
+G + G+GTW+ T ++ + ++ + A D G DTA +Y+ E +G I
Sbjct: 45 SGLRVSCLGLGTWV-TFGGQITDEMAEQLMTLAYDNGINLFDTAEVYAAGKAEVVLGNII 103
Query: 313 KKKIAEGVVKREDLFVTTKL-WNTNHKKEA------VLPALRKSLKNLDLDYVNLYLIHW 471
KKK +R L +TTK+ W + E ++ L+ SL+ L L+YV++ +
Sbjct: 104 KKK----GWRRSSLVITTKIFWGGKAETERGLSRKHIIEGLKASLERLQLEYVDVVFANR 159
Query: 472 PIALHENASISQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQL 603
P T ET +AMT V+NQG+ G S ++ ++
Sbjct: 160 PDP--------NTPMEETVRAMTHVINQGMAMYWGTSRWSSMEI 195
>AL035406-6|CAI19886.1| 253|Homo sapiens potassium voltage-gated
channel, shaker-related subfamily, beta member 2
protein.
Length = 253
Score = 54.4 bits (125), Expect = 5e-07
Identities = 46/164 (28%), Positives = 78/164 (47%), Gaps = 10/164 (6%)
Frame = +1
Query: 142 NGKEIPGFGIGTWLGTNSNELKGD*VQKSVEWAIDAGYRHIDTAAIYST---EDQVGRAI 312
+G + G+GTW+ T ++ + ++ + A D G DTA +Y+ E +G I
Sbjct: 45 SGLRVSCLGLGTWV-TFGGQITDEMAEQLMTLAYDNGINLFDTAEVYAAGKAEVVLGNII 103
Query: 313 KKKIAEGVVKREDLFVTTKL-WNTNHKKEA------VLPALRKSLKNLDLDYVNLYLIHW 471
KKK +R L +TTK+ W + E ++ L+ SL+ L L+YV++ +
Sbjct: 104 KKK----GWRRSSLVITTKIFWGGKAETERGLSRKHIIEGLKASLERLQLEYVDVVFANR 159
Query: 472 PIALHENASISQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQL 603
P T ET +AMT V+NQG+ G S ++ ++
Sbjct: 160 PDP--------NTPMEETVRAMTHVINQGMAMYWGTSRWSSMEI 195
>AL035406-5|CAI19887.1| 254|Homo sapiens potassium voltage-gated
channel, shaker-related subfamily, beta member 2
protein.
Length = 254
Score = 54.4 bits (125), Expect = 5e-07
Identities = 46/164 (28%), Positives = 78/164 (47%), Gaps = 10/164 (6%)
Frame = +1
Query: 142 NGKEIPGFGIGTWLGTNSNELKGD*VQKSVEWAIDAGYRHIDTAAIYST---EDQVGRAI 312
+G + G+GTW+ T ++ + ++ + A D G DTA +Y+ E +G I
Sbjct: 31 SGLRVSCLGLGTWV-TFGGQITDEMAEQLMTLAYDNGINLFDTAEVYAAGKAEVVLGNII 89
Query: 313 KKKIAEGVVKREDLFVTTKL-WNTNHKKEA------VLPALRKSLKNLDLDYVNLYLIHW 471
KKK +R L +TTK+ W + E ++ L+ SL+ L L+YV++ +
Sbjct: 90 KKK----GWRRSSLVITTKIFWGGKAETERGLSRKHIIEGLKASLERLQLEYVDVVFANR 145
Query: 472 PIALHENASISQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQL 603
P T ET +AMT V+NQG+ G S ++ ++
Sbjct: 146 PDP--------NTPMEETVRAMTHVINQGMAMYWGTSRWSSMEI 181
>AL035406-4|CAC08512.1| 367|Homo sapiens potassium voltage-gated
channel, shaker-related subfamily, beta member 2
protein.
Length = 367
Score = 54.4 bits (125), Expect = 5e-07
Identities = 46/164 (28%), Positives = 78/164 (47%), Gaps = 10/164 (6%)
Frame = +1
Query: 142 NGKEIPGFGIGTWLGTNSNELKGD*VQKSVEWAIDAGYRHIDTAAIYST---EDQVGRAI 312
+G + G+GTW+ T ++ + ++ + A D G DTA +Y+ E +G I
Sbjct: 45 SGLRVSCLGLGTWV-TFGGQITDEMAEQLMTLAYDNGINLFDTAEVYAAGKAEVVLGNII 103
Query: 313 KKKIAEGVVKREDLFVTTKL-WNTNHKKEA------VLPALRKSLKNLDLDYVNLYLIHW 471
KKK +R L +TTK+ W + E ++ L+ SL+ L L+YV++ +
Sbjct: 104 KKK----GWRRSSLVITTKIFWGGKAETERGLSRKHIIEGLKASLERLQLEYVDVVFANR 159
Query: 472 PIALHENASISQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQL 603
P T ET +AMT V+NQG+ G S ++ ++
Sbjct: 160 PDP--------NTPMEETVRAMTHVINQGMAMYWGTSRWSSMEI 195
>AL035406-3|CAI19885.1| 353|Homo sapiens potassium voltage-gated
channel, shaker-related subfamily, beta member 2
protein.
Length = 353
Score = 54.4 bits (125), Expect = 5e-07
Identities = 46/164 (28%), Positives = 78/164 (47%), Gaps = 10/164 (6%)
Frame = +1
Query: 142 NGKEIPGFGIGTWLGTNSNELKGD*VQKSVEWAIDAGYRHIDTAAIYST---EDQVGRAI 312
+G + G+GTW+ T ++ + ++ + A D G DTA +Y+ E +G I
Sbjct: 31 SGLRVSCLGLGTWV-TFGGQITDEMAEQLMTLAYDNGINLFDTAEVYAAGKAEVVLGNII 89
Query: 313 KKKIAEGVVKREDLFVTTKL-WNTNHKKEA------VLPALRKSLKNLDLDYVNLYLIHW 471
KKK +R L +TTK+ W + E ++ L+ SL+ L L+YV++ +
Sbjct: 90 KKK----GWRRSSLVITTKIFWGGKAETERGLSRKHIIEGLKASLERLQLEYVDVVFANR 145
Query: 472 PIALHENASISQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQL 603
P T ET +AMT V+NQG+ G S ++ ++
Sbjct: 146 PDP--------NTPMEETVRAMTHVINQGMAMYWGTSRWSSMEI 181
>AF044253-1|AAB99859.1| 353|Homo sapiens potassium channel beta 2
subunit protein.
Length = 353
Score = 54.4 bits (125), Expect = 5e-07
Identities = 46/164 (28%), Positives = 78/164 (47%), Gaps = 10/164 (6%)
Frame = +1
Query: 142 NGKEIPGFGIGTWLGTNSNELKGD*VQKSVEWAIDAGYRHIDTAAIYST---EDQVGRAI 312
+G + G+GTW+ T ++ + ++ + A D G DTA +Y+ E +G I
Sbjct: 31 SGLRVSCLGLGTWV-TFGGQITDEMAEQLMTLAYDNGINLFDTAEVYAAGKAEVVLGNII 89
Query: 313 KKKIAEGVVKREDLFVTTKL-WNTNHKKEA------VLPALRKSLKNLDLDYVNLYLIHW 471
KKK +R L +TTK+ W + E ++ L+ SL+ L L+YV++ +
Sbjct: 90 KKK----GWRRSSLVITTKIFWGGKAETERGLSRKHIIEGLKASLERLQLEYVDVVFANR 145
Query: 472 PIALHENASISQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQL 603
P T ET +AMT V+NQG+ G S ++ ++
Sbjct: 146 PDP--------NTPMEETVRAMTHVINQGMAMYWGTSRWSSMEI 181
>AF029749-1|AAB84170.1| 367|Homo sapiens potassium channel beta 2
subunit protein.
Length = 367
Score = 54.4 bits (125), Expect = 5e-07
Identities = 46/164 (28%), Positives = 78/164 (47%), Gaps = 10/164 (6%)
Frame = +1
Query: 142 NGKEIPGFGIGTWLGTNSNELKGD*VQKSVEWAIDAGYRHIDTAAIYST---EDQVGRAI 312
+G + G+GTW+ T ++ + ++ + A D G DTA +Y+ E +G I
Sbjct: 45 SGLRVSCLGLGTWV-TFGGQITDEMAEQLMTLAYDNGINLFDTAEVYAAGKAEVVLGNII 103
Query: 313 KKKIAEGVVKREDLFVTTKL-WNTNHKKEA------VLPALRKSLKNLDLDYVNLYLIHW 471
KKK +R L +TTK+ W + E ++ L+ SL+ L L+YV++ +
Sbjct: 104 KKK----GWRRSSLVITTKIFWGGKAETERGLSRKHIIEGLKASLERLQLEYVDVVFANR 159
Query: 472 PIALHENASISQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQL 603
P T ET +AMT V+NQG+ G S ++ ++
Sbjct: 160 PDP--------NTPMEETVRAMTHVINQGMAMYWGTSRWSSMEI 195
>X83127-1|CAA58208.1| 401|Homo sapiens voltage gated potassium
channels, beta subunit protein.
Length = 401
Score = 54.0 bits (124), Expect = 7e-07
Identities = 46/164 (28%), Positives = 79/164 (48%), Gaps = 10/164 (6%)
Frame = +1
Query: 142 NGKEIPGFGIGTWLGTNSNELKGD*VQKSVEWAIDAGYRHIDTAAIYST---EDQVGRAI 312
+G + G+GTW+ T ++ + ++ + A ++G DTA +Y+ E +G I
Sbjct: 79 SGLRVSCLGLGTWV-TFGGQISDEVAERLMTIAYESGVNLFDTAEVYAAGKAEVILGSII 137
Query: 313 KKKIAEGVVKREDLFVTTKL-WNTNHKKEA------VLPALRKSLKNLDLDYVNLYLIHW 471
KKK +R L +TTKL W + E ++ L+ SL+ L L+YV++ +
Sbjct: 138 KKK----GWRRSSLVITTKLYWGGKAETERGLSRKHIIEGLKGSLQRLQLEYVDVVFANR 193
Query: 472 PIALHENASISQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQL 603
P S T E +AMT V+NQG+ G S ++ ++
Sbjct: 194 PD--------SNTPMEEIVRAMTHVINQGMAMYWGTSRWSAMEI 229
>U33428-1|AAC50953.1| 401|Homo sapiens K+ channel beta 1a subunit
protein.
Length = 401
Score = 54.0 bits (124), Expect = 7e-07
Identities = 46/164 (28%), Positives = 79/164 (48%), Gaps = 10/164 (6%)
Frame = +1
Query: 142 NGKEIPGFGIGTWLGTNSNELKGD*VQKSVEWAIDAGYRHIDTAAIYST---EDQVGRAI 312
+G + G+GTW+ T ++ + ++ + A ++G DTA +Y+ E +G I
Sbjct: 79 SGLRVSCLGLGTWV-TFGGQISDEVAERLMTIAYESGVNLFDTAEVYAAGKAEVILGSII 137
Query: 313 KKKIAEGVVKREDLFVTTKL-WNTNHKKEA------VLPALRKSLKNLDLDYVNLYLIHW 471
KKK +R L +TTKL W + E ++ L+ SL+ L L+YV++ +
Sbjct: 138 KKK----GWRRSSLVITTKLYWGGKAETERGLSRKHIIEGLKGSLQRLQLEYVDVVFANR 193
Query: 472 PIALHENASISQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQL 603
P S T E +AMT V+NQG+ G S ++ ++
Sbjct: 194 PD--------SNTPMEEIVRAMTHVINQGMAMYWGTSRWSAMEI 229
>U16953-1|AAC50122.1| 408|Homo sapiens potassium channel beta3
subunit protein.
Length = 408
Score = 54.0 bits (124), Expect = 7e-07
Identities = 46/164 (28%), Positives = 79/164 (48%), Gaps = 10/164 (6%)
Frame = +1
Query: 142 NGKEIPGFGIGTWLGTNSNELKGD*VQKSVEWAIDAGYRHIDTAAIYST---EDQVGRAI 312
+G + G+GTW+ T ++ + ++ + A ++G DTA +Y+ E +G I
Sbjct: 86 SGLRVSCLGLGTWV-TFGGQISDEVAERLMTIAYESGVNLFDTAEVYAAGKAEVILGSII 144
Query: 313 KKKIAEGVVKREDLFVTTKL-WNTNHKKEA------VLPALRKSLKNLDLDYVNLYLIHW 471
KKK +R L +TTKL W + E ++ L+ SL+ L L+YV++ +
Sbjct: 145 KKK----GWRRSSLVITTKLYWGGKAETERGLSRKHIIEGLKGSLQRLQLEYVDVVFANR 200
Query: 472 PIALHENASISQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQL 603
P S T E +AMT V+NQG+ G S ++ ++
Sbjct: 201 PD--------SNTPMEEIVRAMTHVINQGMAMYWGTSRWSAMEI 236
>L47665-1|AAC41926.1| 419|Homo sapiens K+ channel beta-subunit
protein.
Length = 419
Score = 54.0 bits (124), Expect = 7e-07
Identities = 46/164 (28%), Positives = 79/164 (48%), Gaps = 10/164 (6%)
Frame = +1
Query: 142 NGKEIPGFGIGTWLGTNSNELKGD*VQKSVEWAIDAGYRHIDTAAIYST---EDQVGRAI 312
+G + G+GTW+ T ++ + ++ + A ++G DTA +Y+ E +G I
Sbjct: 97 SGLRVSCLGLGTWV-TFGGQISDEVAERLMTIAYESGVNLFDTAEVYAAGKAEVILGSII 155
Query: 313 KKKIAEGVVKREDLFVTTKL-WNTNHKKEA------VLPALRKSLKNLDLDYVNLYLIHW 471
KKK +R L +TTKL W + E ++ L+ SL+ L L+YV++ +
Sbjct: 156 KKK----GWRRSSLVITTKLYWGGKAETERGLSRKHIIEGLKGSLQRLQLEYVDVVFANR 211
Query: 472 PIALHENASISQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQL 603
P S T E +AMT V+NQG+ G S ++ ++
Sbjct: 212 PD--------SNTPMEEIVRAMTHVINQGMAMYWGTSRWSAMEI 247
>L39833-1|AAC37573.1| 408|Homo sapiens K+ channel beta-subunit
protein.
Length = 408
Score = 54.0 bits (124), Expect = 7e-07
Identities = 46/164 (28%), Positives = 79/164 (48%), Gaps = 10/164 (6%)
Frame = +1
Query: 142 NGKEIPGFGIGTWLGTNSNELKGD*VQKSVEWAIDAGYRHIDTAAIYST---EDQVGRAI 312
+G + G+GTW+ T ++ + ++ + A ++G DTA +Y+ E +G I
Sbjct: 86 SGLRVSCLGLGTWV-TFGGQISDEVAERLMTIAYESGVNLFDTAEVYAAGKAEVILGSII 144
Query: 313 KKKIAEGVVKREDLFVTTKL-WNTNHKKEA------VLPALRKSLKNLDLDYVNLYLIHW 471
KKK +R L +TTKL W + E ++ L+ SL+ L L+YV++ +
Sbjct: 145 KKK----GWRRSSLVITTKLYWGGKAETERGLSRKHIIEGLKGSLQRLQLEYVDVVFANR 200
Query: 472 PIALHENASISQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQL 603
P S T E +AMT V+NQG+ G S ++ ++
Sbjct: 201 PD--------SNTPMEEIVRAMTHVINQGMAMYWGTSRWSAMEI 236
>BC043166-1|AAH43166.1| 401|Homo sapiens potassium voltage-gated
channel, shaker-related subfamily, beta member 1
protein.
Length = 401
Score = 54.0 bits (124), Expect = 7e-07
Identities = 46/164 (28%), Positives = 79/164 (48%), Gaps = 10/164 (6%)
Frame = +1
Query: 142 NGKEIPGFGIGTWLGTNSNELKGD*VQKSVEWAIDAGYRHIDTAAIYST---EDQVGRAI 312
+G + G+GTW+ T ++ + ++ + A ++G DTA +Y+ E +G I
Sbjct: 79 SGLRVSCLGLGTWV-TFGGQISDEVAERLMTIAYESGVNLFDTAEVYAAGKAEVILGSII 137
Query: 313 KKKIAEGVVKREDLFVTTKL-WNTNHKKEA------VLPALRKSLKNLDLDYVNLYLIHW 471
KKK +R L +TTKL W + E ++ L+ SL+ L L+YV++ +
Sbjct: 138 KKK----GWRRSSLVITTKLYWGGKAETERGLSRKHIIEGLKGSLQRLQLEYVDVVFANR 193
Query: 472 PIALHENASISQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQL 603
P S T E +AMT V+NQG+ G S ++ ++
Sbjct: 194 PD--------SNTPMEEIVRAMTHVINQGMAMYWGTSRWSAMEI 229
>AK131252-1|BAD18431.1| 415|Homo sapiens protein ( Homo sapiens
cDNA FLJ16180 fis, clone BRHIP3000240, highly similar
to Homo sapiens potassium channel beta 2 subunit
(HKvbeta2.2) mRNA. ).
Length = 415
Score = 53.6 bits (123), Expect = 9e-07
Identities = 48/171 (28%), Positives = 84/171 (49%), Gaps = 17/171 (9%)
Frame = +1
Query: 142 NGKEIPGFGIGTWLGTNSNELKGD*VQKSVEWAIDAGYRHIDTAAIYST---EDQVGRAI 312
+G + G+GTW+ T ++ + ++ + A D G DTA +Y+ E +G I
Sbjct: 78 SGLRVSCLGLGTWV-TFGGQITDEMAEQLMTLAYDNGINLFDTAEVYAAGKAEVVLGNII 136
Query: 313 KKKIAEGVVKREDLFVTTKL-WNTNHKKEA------VLPALRKSLKNLDLDYVNLYLIHW 471
KKK +R L +TTK+ W + E ++ L+ SL+ L L+YV++ +
Sbjct: 137 KKK----GWRRSSLVITTKIFWGGKAETERGLSRKHIIEGLKASLERLQLEYVDVVFANR 192
Query: 472 PIALHE------NASISQTDYVE-TWQAMTDVLNQGLTKSIGVSNFNIQQL 603
P ++S S+T +E T +AMT V+NQG+ G S ++ ++
Sbjct: 193 PDPNTPMEGDPFSSSKSRTFIIEETVRAMTHVINQGMAMYWGTSRWSSMEI 243
>CR542264-1|CAG47060.1| 353|Homo sapiens KCNAB2 protein.
Length = 353
Score = 52.4 bits (120), Expect = 2e-06
Identities = 54/219 (24%), Positives = 98/219 (44%), Gaps = 17/219 (7%)
Frame = +1
Query: 142 NGKEIPGFGIGTWLGTNSNELKGD*VQKSVEWAIDAGYRHIDTAAIYST---EDQVGRAI 312
+G + G+GTW+ T ++ + ++ + A D G DTA +Y+ E +G I
Sbjct: 31 SGLRVSCLGLGTWV-TFGGQITDEMAEQLMTLAYDNGINLFDTAEVYAAGKAEVVLGNII 89
Query: 313 KKKIAEGVVKREDLFVTTKL-WNTNHKKEA------VLPALRKSLKNLDLDYVNLYLIHW 471
KKK +R L +TTK+ W + E ++ L+ SL+ L+YV++ +
Sbjct: 90 KKK----GWRRSSLVITTKIFWGGKAETERGLSRKHIIEGLKASLERRQLEYVDVVFANR 145
Query: 472 PIALHENASISQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLEXLKSXG---GVTPSV 642
P T ET +AMT V+NQG+ G S ++ ++ S +TP +
Sbjct: 146 PDP--------NTPMEETVRAMTHVINQGMAMYWGTSRWSSMEIMEAYSVARQFNLTPPI 197
Query: 643 L-QVEINLNLQRSA---LLDYCKAQGIXVVAYTPLRXSV 747
Q E +++ + L + G+ + ++PL +
Sbjct: 198 CEQAEYHMSQREKVEVQLPELFHKIGVGAMTWSPLACGI 236
>BC099634-1|AAH99634.1| 404|Homo sapiens potassium voltage-gated
channel, shaker-related subfamily, beta member 3
protein.
Length = 404
Score = 44.8 bits (101), Expect = 4e-04
Identities = 40/161 (24%), Positives = 71/161 (44%), Gaps = 7/161 (4%)
Frame = +1
Query: 142 NGKEIPGFGIGTWLGTNSNELKGD*VQKSVEWAIDAGYRHIDTAAIYSTEDQVGRAIKKK 321
+G + G+GTW+ T +++ + + + A + G DTA +Y+ + R +
Sbjct: 86 SGLRVSCLGLGTWV-TFGSQISDETAEDVLTVAYEHGVNLFDTAEVYAA-GKAERTLGNI 143
Query: 322 IAEGVVKREDLFVTTKL-WNTNHKKEA------VLPALRKSLKNLDLDYVNLYLIHWPIA 480
+ +R +TTK+ W + E ++ LR SL+ L L YV++
Sbjct: 144 LKSKGWRRSSYVITTKIFWGGQAETERGLSRKHIIEGLRGSLERLQLGYVDI-------- 195
Query: 481 LHENASISQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQL 603
+ N S E +AMT V+NQGL G S + ++
Sbjct: 196 VFANRSDPNCPMEEIVRAMTYVINQGLALYWGTSRWGAAEI 236
>BC096234-1|AAH96234.1| 404|Homo sapiens potassium voltage-gated
channel, shaker-related subfamily, beta member 3
protein.
Length = 404
Score = 44.8 bits (101), Expect = 4e-04
Identities = 40/161 (24%), Positives = 71/161 (44%), Gaps = 7/161 (4%)
Frame = +1
Query: 142 NGKEIPGFGIGTWLGTNSNELKGD*VQKSVEWAIDAGYRHIDTAAIYSTEDQVGRAIKKK 321
+G + G+GTW+ T +++ + + + A + G DTA +Y+ + R +
Sbjct: 86 SGLRVSCLGLGTWV-TFGSQISDETAEDVLTVAYEHGVNLFDTAEVYAA-GKAERTLGNI 143
Query: 322 IAEGVVKREDLFVTTKL-WNTNHKKEA------VLPALRKSLKNLDLDYVNLYLIHWPIA 480
+ +R +TTK+ W + E ++ LR SL+ L L YV++
Sbjct: 144 LKSKGWRRSSYVITTKIFWGGQAETERGLSRKHIIEGLRGSLERLQLGYVDI-------- 195
Query: 481 LHENASISQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQL 603
+ N S E +AMT V+NQGL G S + ++
Sbjct: 196 VFANRSDPNCPMEEIVRAMTYVINQGLALYWGTSRWGAAEI 236
>BC096232-1|AAH96232.1| 404|Homo sapiens potassium voltage-gated
channel, shaker-related subfamily, beta member 3
protein.
Length = 404
Score = 44.8 bits (101), Expect = 4e-04
Identities = 40/161 (24%), Positives = 71/161 (44%), Gaps = 7/161 (4%)
Frame = +1
Query: 142 NGKEIPGFGIGTWLGTNSNELKGD*VQKSVEWAIDAGYRHIDTAAIYSTEDQVGRAIKKK 321
+G + G+GTW+ T +++ + + + A + G DTA +Y+ + R +
Sbjct: 86 SGLRVSCLGLGTWV-TFGSQISDETAEDVLTVAYEHGVNLFDTAEVYAA-GKAERTLGNI 143
Query: 322 IAEGVVKREDLFVTTKL-WNTNHKKEA------VLPALRKSLKNLDLDYVNLYLIHWPIA 480
+ +R +TTK+ W + E ++ LR SL+ L L YV++
Sbjct: 144 LKSKGWRRSSYVITTKIFWGGQAETERGLSRKHIIEGLRGSLERLQLGYVDI-------- 195
Query: 481 LHENASISQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQL 603
+ N S E +AMT V+NQGL G S + ++
Sbjct: 196 VFANRSDPNCPMEEIVRAMTYVINQGLALYWGTSRWGAAEI 236
>AF016411-1|AAB92499.1| 404|Homo sapiens KCNA3.1B protein.
Length = 404
Score = 44.4 bits (100), Expect = 6e-04
Identities = 40/160 (25%), Positives = 70/160 (43%), Gaps = 7/160 (4%)
Frame = +1
Query: 145 GKEIPGFGIGTWLGTNSNELKGD*VQKSVEWAIDAGYRHIDTAAIYSTEDQVGRAIKKKI 324
G + G+GTW+ T +++ + + + A + G DTA +Y+ + R + +
Sbjct: 87 GVRVSCLGLGTWV-TFGSQISDETAEDVLTVAYEHGVNLFDTAEVYAA-GKAERTLGNIL 144
Query: 325 AEGVVKREDLFVTTKL-WNTNHKKEA------VLPALRKSLKNLDLDYVNLYLIHWPIAL 483
+R +TTK+ W + E ++ LR SL+ L L YV++ +
Sbjct: 145 KSKGWRRSSYVITTKIFWGGQAETERGLSRKHIIEGLRGSLERLQLGYVDI--------V 196
Query: 484 HENASISQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQL 603
N S E +AMT V+NQGL G S + ++
Sbjct: 197 FANRSDPNCPMEEIVRAMTYVINQGLALYWGTSRWGAAEI 236
>AB028065-1|BAA88489.1| 67|Homo sapiens prostaglandin F synthase
protein.
Length = 67
Score = 42.7 bits (96), Expect = 0.002
Identities = 20/40 (50%), Positives = 26/40 (65%)
Frame = +1
Query: 511 DYVETWQAMTDVLNQGLTKSIGVSNFNIQQLEXLKSXGGV 630
D TW+AM + GL KSIGVSNFN +QLE + + G+
Sbjct: 20 DLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGL 59
>AB037905-2|BAA92890.1| 45|Homo sapiens truncated aldo-keto
reductase protein.
Length = 45
Score = 40.3 bits (90), Expect = 0.009
Identities = 18/43 (41%), Positives = 24/43 (55%)
Frame = +1
Query: 370 LWNTNHKKEAVLPALRKSLKNLDLDYVNLYLIHWPIALHENAS 498
+W T + E V L SLK L L Y++LYL H+P+ L S
Sbjct: 1 VWGTFSRPELVQRGLEMSLKKLQLSYMDLYLFHFPVPLQPGRS 43
>AJ278012-1|CAC79668.1| 259|Homo sapiens aflatoxin B1 aldehyde
reductase 3 protein.
Length = 259
Score = 35.9 bits (79), Expect = 0.20
Identities = 32/122 (26%), Positives = 56/122 (45%), Gaps = 6/122 (4%)
Frame = +1
Query: 388 KKEAVLPALRKSLKNLDLDYVNLYLIHWPIALHENASISQTDYVETWQAMTDVLNQGLTK 567
K ++V L SLK L V+L+ +H P +A + ET +A + +G
Sbjct: 15 KPDSVRSQLETSLKRLQCPUVDLFYLHAP---DHSAPVE-----ETLRACHQLHQEGKFV 66
Query: 568 SIGVSNFNIQQLEXL----KSXGGVTPSVLQVEINLNLQR--SALLDYCKAQGIXVVAYT 729
+G+SN+ ++ + KS G + P+V Q + ++ + L Y + G+ AY
Sbjct: 67 ELGLSNYAAWEVAEICTLCKSNGWILPTVYQGMYSATTRQVETELFPYLRHFGLRFYAYN 126
Query: 730 PL 735
PL
Sbjct: 127 PL 128
>AF026947-1|AAC52104.1| 330|Homo sapiens aflatoxin aldehyde
reductase AFAR protein.
Length = 330
Score = 35.5 bits (78), Expect = 0.27
Identities = 44/175 (25%), Positives = 75/175 (42%), Gaps = 10/175 (5%)
Frame = +1
Query: 241 IDAGYRHIDTAAIYSTEDQVGRAIKKKIAEGVVKRE-DLFVTTKL--WNTNH-KKEAVLP 408
++ G+ +DTA +YS D I + G+ + + + TK W+ K ++V
Sbjct: 35 LERGHTELDTAFMYS--DGQSETILGGLGLGLGGGDCRVKIATKANPWDGKSLKPDSVRS 92
Query: 409 ALRKSLKNLDLDYVNLYLIHWPIALHENASISQTDYVETWQAMTDVLNQGLTKSIGVSNF 588
L SLK L V+L+ +H P T ET A + +G +G+SN+
Sbjct: 93 QLETSLKRLQCPQVDLFYLHTP--------DHGTPVEETLHACQRLHQEGKFVELGLSNY 144
Query: 589 NIQQLEXL----KSXGGVTPSVLQVEINLNLQR--SALLDYCKAQGIXVVAYTPL 735
++ + KS G + P+V Q N ++ + L + G+ AY PL
Sbjct: 145 ASWEVAEICTLCKSNGWILPTVYQGMYNATTRQVETELFPCLRHFGLRFYAYNPL 199
>Y16675-1|CAA76347.1| 330|Homo sapiens aflatoxin B1-aldehyde
reductase protein.
Length = 330
Score = 35.1 bits (77), Expect = 0.35
Identities = 44/175 (25%), Positives = 75/175 (42%), Gaps = 10/175 (5%)
Frame = +1
Query: 241 IDAGYRHIDTAAIYSTEDQVGRAIKKKIAEGVVKRE-DLFVTTKL--WNTNH-KKEAVLP 408
++ G+ +DTA +YS D I + G+ + + + TK W+ K ++V
Sbjct: 35 LERGHTELDTAFMYS--DGQSETILGGLGLGLGGGDCRVKIATKANPWDGKSLKPDSVRS 92
Query: 409 ALRKSLKNLDLDYVNLYLIHWPIALHENASISQTDYVETWQAMTDVLNQGLTKSIGVSNF 588
L SLK L V+L+ +H P T ET A + +G +G+SN+
Sbjct: 93 QLETSLKRLQCPQVDLFYLHAP--------DHGTPVEETLHACQRLHQEGKFVELGLSNY 144
Query: 589 NIQQLEXL----KSXGGVTPSVLQVEINLNLQR--SALLDYCKAQGIXVVAYTPL 735
++ + KS G + P+V Q N ++ + L + G+ AY PL
Sbjct: 145 ASWEVAEICTLCKSNGWILPTVYQGMYNATTRQVETELFPCLRHFGLRFYAYNPL 199
>BT007347-1|AAP36011.1| 330|Homo sapiens aldo-keto reductase family
7, member A2 (aflatoxin aldehyde reductase) protein.
Length = 330
Score = 35.1 bits (77), Expect = 0.35
Identities = 44/175 (25%), Positives = 75/175 (42%), Gaps = 10/175 (5%)
Frame = +1
Query: 241 IDAGYRHIDTAAIYSTEDQVGRAIKKKIAEGVVKRE-DLFVTTKL--WNTNH-KKEAVLP 408
++ G+ +DTA +YS D I + G+ + + + TK W+ K ++V
Sbjct: 35 LERGHTELDTAFMYS--DGQSETILGGLGLGLGGGDCRVKIATKANPWDGKSLKPDSVRS 92
Query: 409 ALRKSLKNLDLDYVNLYLIHWPIALHENASISQTDYVETWQAMTDVLNQGLTKSIGVSNF 588
L SLK L V+L+ +H P T ET A + +G +G+SN+
Sbjct: 93 QLETSLKRLQCPQVDLFYLHAP--------DHGTPVEETLHACQRLHQEGKFVELGLSNY 144
Query: 589 NIQQLEXL----KSXGGVTPSVLQVEINLNLQR--SALLDYCKAQGIXVVAYTPL 735
++ + KS G + P+V Q N ++ + L + G+ AY PL
Sbjct: 145 ASWEVAEICTLCKSNGWILPTVYQGMYNATTRQVETELFPCLRHFGLRFYAYNPL 199
>BC013996-1|AAH13996.1| 330|Homo sapiens AKR7A2 protein protein.
Length = 330
Score = 35.1 bits (77), Expect = 0.35
Identities = 44/175 (25%), Positives = 75/175 (42%), Gaps = 10/175 (5%)
Frame = +1
Query: 241 IDAGYRHIDTAAIYSTEDQVGRAIKKKIAEGVVKRE-DLFVTTKL--WNTNH-KKEAVLP 408
++ G+ +DTA +YS D I + G+ + + + TK W+ K ++V
Sbjct: 35 LERGHTELDTAFMYS--DGQSETILGGLGLGLGGGDCRVKIATKANPWDGKSLKPDSVRS 92
Query: 409 ALRKSLKNLDLDYVNLYLIHWPIALHENASISQTDYVETWQAMTDVLNQGLTKSIGVSNF 588
L SLK L V+L+ +H P T ET A + +G +G+SN+
Sbjct: 93 QLETSLKRLQCPQVDLFYLHAP--------DHGTPVEETLHACQRLHQEGKFVELGLSNY 144
Query: 589 NIQQLEXL----KSXGGVTPSVLQVEINLNLQR--SALLDYCKAQGIXVVAYTPL 735
++ + KS G + P+V Q N ++ + L + G+ AY PL
Sbjct: 145 ASWEVAEICTLCKSNGWILPTVYQGMYNATTRQVETELFPCLRHFGLRFYAYNPL 199
>BC012171-1|AAH12171.1| 330|Homo sapiens AKR7A2 protein protein.
Length = 330
Score = 35.1 bits (77), Expect = 0.35
Identities = 44/175 (25%), Positives = 75/175 (42%), Gaps = 10/175 (5%)
Frame = +1
Query: 241 IDAGYRHIDTAAIYSTEDQVGRAIKKKIAEGVVKRE-DLFVTTKL--WNTNH-KKEAVLP 408
++ G+ +DTA +YS D I + G+ + + + TK W+ K ++V
Sbjct: 35 LERGHTELDTAFMYS--DGQSETILGGLGLGLGGGDCRVKIATKANPWDGKSLKPDSVRS 92
Query: 409 ALRKSLKNLDLDYVNLYLIHWPIALHENASISQTDYVETWQAMTDVLNQGLTKSIGVSNF 588
L SLK L V+L+ +H P T ET A + +G +G+SN+
Sbjct: 93 QLETSLKRLQCPQVDLFYLHAP--------DHGTPVEETLHACQRLHQEGKFVELGLSNY 144
Query: 589 NIQQLEXL----KSXGGVTPSVLQVEINLNLQR--SALLDYCKAQGIXVVAYTPL 735
++ + KS G + P+V Q N ++ + L + G+ AY PL
Sbjct: 145 ASWEVAEICTLCKSNGWILPTVYQGMYNATTRQVETELFPCLRHFGLRFYAYNPL 199
>BC011586-1|AAH11586.1| 330|Homo sapiens AKR7A2 protein protein.
Length = 330
Score = 35.1 bits (77), Expect = 0.35
Identities = 44/175 (25%), Positives = 75/175 (42%), Gaps = 10/175 (5%)
Frame = +1
Query: 241 IDAGYRHIDTAAIYSTEDQVGRAIKKKIAEGVVKRE-DLFVTTKL--WNTNH-KKEAVLP 408
++ G+ +DTA +YS D I + G+ + + + TK W+ K ++V
Sbjct: 35 LERGHTELDTAFMYS--DGQSETILGGLGLGLGGGDCRVKIATKANPWDGKSLKPDSVRS 92
Query: 409 ALRKSLKNLDLDYVNLYLIHWPIALHENASISQTDYVETWQAMTDVLNQGLTKSIGVSNF 588
L SLK L V+L+ +H P T ET A + +G +G+SN+
Sbjct: 93 QLETSLKRLQCPQVDLFYLHAP--------DHGTPVEETLHACQRLHQEGKFVELGLSNY 144
Query: 589 NIQQLEXL----KSXGGVTPSVLQVEINLNLQR--SALLDYCKAQGIXVVAYTPL 735
++ + KS G + P+V Q N ++ + L + G+ AY PL
Sbjct: 145 ASWEVAEICTLCKSNGWILPTVYQGMYNATTRQVETELFPCLRHFGLRFYAYNPL 199
>BC010852-1|AAH10852.1| 330|Homo sapiens AKR7A2 protein protein.
Length = 330
Score = 35.1 bits (77), Expect = 0.35
Identities = 44/175 (25%), Positives = 75/175 (42%), Gaps = 10/175 (5%)
Frame = +1
Query: 241 IDAGYRHIDTAAIYSTEDQVGRAIKKKIAEGVVKRE-DLFVTTKL--WNTNH-KKEAVLP 408
++ G+ +DTA +YS D I + G+ + + + TK W+ K ++V
Sbjct: 35 LERGHTELDTAFMYS--DGQSETILGGLGLGLGGGDCRVKIATKANPWDGKSLKPDSVRS 92
Query: 409 ALRKSLKNLDLDYVNLYLIHWPIALHENASISQTDYVETWQAMTDVLNQGLTKSIGVSNF 588
L SLK L V+L+ +H P T ET A + +G +G+SN+
Sbjct: 93 QLETSLKRLQCPQVDLFYLHAP--------DHGTPVEETLHACQRLHQEGKFVELGLSNY 144
Query: 589 NIQQLEXL----KSXGGVTPSVLQVEINLNLQR--SALLDYCKAQGIXVVAYTPL 735
++ + KS G + P+V Q N ++ + L + G+ AY PL
Sbjct: 145 ASWEVAEICTLCKSNGWILPTVYQGMYNATTRQVETELFPCLRHFGLRFYAYNPL 199
>BC007352-1|AAH07352.2| 358|Homo sapiens AKR7A2 protein protein.
Length = 358
Score = 35.1 bits (77), Expect = 0.35
Identities = 44/175 (25%), Positives = 75/175 (42%), Gaps = 10/175 (5%)
Frame = +1
Query: 241 IDAGYRHIDTAAIYSTEDQVGRAIKKKIAEGVVKRE-DLFVTTKL--WNTNH-KKEAVLP 408
++ G+ +DTA +YS D I + G+ + + + TK W+ K ++V
Sbjct: 63 LERGHTELDTAFMYS--DGQSETILGGLGLGLGGGDCRVKIATKANPWDGKSLKPDSVRS 120
Query: 409 ALRKSLKNLDLDYVNLYLIHWPIALHENASISQTDYVETWQAMTDVLNQGLTKSIGVSNF 588
L SLK L V+L+ +H P T ET A + +G +G+SN+
Sbjct: 121 QLETSLKRLQCPQVDLFYLHAP--------DHGTPVEETLHACQRLHQEGKFVELGLSNY 172
Query: 589 NIQQLEXL----KSXGGVTPSVLQVEINLNLQR--SALLDYCKAQGIXVVAYTPL 735
++ + KS G + P+V Q N ++ + L + G+ AY PL
Sbjct: 173 ASWEVAEICTLCKSNGWILPTVYQGMYNATTRQVETELFPCLRHFGLRFYAYNPL 227
>BC004111-1|AAH04111.3| 330|Homo sapiens AKR7A2 protein protein.
Length = 330
Score = 35.1 bits (77), Expect = 0.35
Identities = 44/175 (25%), Positives = 75/175 (42%), Gaps = 10/175 (5%)
Frame = +1
Query: 241 IDAGYRHIDTAAIYSTEDQVGRAIKKKIAEGVVKRE-DLFVTTKL--WNTNH-KKEAVLP 408
++ G+ +DTA +YS D I + G+ + + + TK W+ K ++V
Sbjct: 35 LERGHTELDTAFMYS--DGQSETILGGLGLGLGGGDCRVKIATKANPWDGKSLKPDSVRS 92
Query: 409 ALRKSLKNLDLDYVNLYLIHWPIALHENASISQTDYVETWQAMTDVLNQGLTKSIGVSNF 588
L SLK L V+L+ +H P T ET A + +G +G+SN+
Sbjct: 93 QLETSLKRLQCPQVDLFYLHAP--------DHGTPVEETLHACQRLHQEGKFVELGLSNY 144
Query: 589 NIQQLEXL----KSXGGVTPSVLQVEINLNLQR--SALLDYCKAQGIXVVAYTPL 735
++ + KS G + P+V Q N ++ + L + G+ AY PL
Sbjct: 145 ASWEVAEICTLCKSNGWILPTVYQGMYNATTRQVETELFPCLRHFGLRFYAYNPL 199
>AL035413-8|CAB72321.1| 330|Homo sapiens aldo-keto reductase family
7, member A2 (aflatoxin aldehyde reductase) protein.
Length = 330
Score = 35.1 bits (77), Expect = 0.35
Identities = 44/175 (25%), Positives = 75/175 (42%), Gaps = 10/175 (5%)
Frame = +1
Query: 241 IDAGYRHIDTAAIYSTEDQVGRAIKKKIAEGVVKRE-DLFVTTKL--WNTNH-KKEAVLP 408
++ G+ +DTA +YS D I + G+ + + + TK W+ K ++V
Sbjct: 35 LERGHTELDTAFMYS--DGQSETILGGLGLGLGGGDCRVKIATKANPWDGKSLKPDSVRS 92
Query: 409 ALRKSLKNLDLDYVNLYLIHWPIALHENASISQTDYVETWQAMTDVLNQGLTKSIGVSNF 588
L SLK L V+L+ +H P T ET A + +G +G+SN+
Sbjct: 93 QLETSLKRLQCPQVDLFYLHAP--------DHGTPVEETLHACQRLHQEGKFVELGLSNY 144
Query: 589 NIQQLEXL----KSXGGVTPSVLQVEINLNLQR--SALLDYCKAQGIXVVAYTPL 735
++ + KS G + P+V Q N ++ + L + G+ AY PL
Sbjct: 145 ASWEVAEICTLCKSNGWILPTVYQGMYNATTRQVETELFPCLRHFGLRFYAYNPL 199
>BC042420-1|AAH42420.2| 331|Homo sapiens aldo-keto reductase family
7, member A3 (aflatoxin aldehyde reductase) protein.
Length = 331
Score = 34.3 bits (75), Expect = 0.62
Identities = 41/175 (23%), Positives = 76/175 (43%), Gaps = 10/175 (5%)
Frame = +1
Query: 241 IDAGYRHIDTAAIYSTEDQV----GRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLP 408
++ G+ IDTA +YS G ++ ++ VK + + L+ + K +++
Sbjct: 36 LERGHTEIDTAFVYSEGQSETILGGLGLRLGGSDCRVKIDTKAIP--LFGNSLKPDSLRF 93
Query: 409 ALRKSLKNLDLDYVNLYLIHWPIALHENASISQTDYVETWQAMTDVLNQGLTKSIGVSNF 588
L SLK L V+L+ +H P T ET +A + +G +G+SN+
Sbjct: 94 QLETSLKRLQCPRVDLFYLHMP--------DHSTPVEETLRACHQLHQEGKFMELGLSNY 145
Query: 589 NIQQLEXL----KSXGGVTPSVLQVEINLNLQR--SALLDYCKAQGIXVVAYTPL 735
++ + KS G + P+V Q N ++ + L + G+ A+ PL
Sbjct: 146 AAWEVAEICTLCKSNGWILPTVYQGMYNAITRQVETELFPCLRHFGLRFYAFNPL 200
>BC031562-1|AAH31562.1| 331|Homo sapiens aldo-keto reductase family
7, member A3 (aflatoxin aldehyde reductase) protein.
Length = 331
Score = 34.3 bits (75), Expect = 0.62
Identities = 41/175 (23%), Positives = 76/175 (43%), Gaps = 10/175 (5%)
Frame = +1
Query: 241 IDAGYRHIDTAAIYSTEDQV----GRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLP 408
++ G+ IDTA +YS G ++ ++ VK + + L+ + K +++
Sbjct: 36 LERGHTEIDTAFVYSEGQSETILGGLGLRLGGSDCRVKIDTKAIP--LFGNSLKPDSLRF 93
Query: 409 ALRKSLKNLDLDYVNLYLIHWPIALHENASISQTDYVETWQAMTDVLNQGLTKSIGVSNF 588
L SLK L V+L+ +H P T ET +A + +G +G+SN+
Sbjct: 94 QLETSLKRLQCPRVDLFYLHMP--------DHSTPVEETLRACHQLHQEGKFMELGLSNY 145
Query: 589 NIQQLEXL----KSXGGVTPSVLQVEINLNLQR--SALLDYCKAQGIXVVAYTPL 735
++ + KS G + P+V Q N ++ + L + G+ A+ PL
Sbjct: 146 AAWEVAEICTLCKSNGWILPTVYQGMYNAITRQVETELFPCLRHFGLRFYAFNPL 200
>AJ271799-1|CAC81076.1| 331|Homo sapiens aflatoxin B1 aldehyde
reductase 2 protein.
Length = 331
Score = 34.3 bits (75), Expect = 0.62
Identities = 41/175 (23%), Positives = 76/175 (43%), Gaps = 10/175 (5%)
Frame = +1
Query: 241 IDAGYRHIDTAAIYSTEDQV----GRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLP 408
++ G+ IDTA +YS G ++ ++ VK + + L+ + K +++
Sbjct: 36 LERGHTEIDTAFVYSEGQSETILGGLGLRLGGSDCRVKIDTKAIP--LFGNSLKPDSLRF 93
Query: 409 ALRKSLKNLDLDYVNLYLIHWPIALHENASISQTDYVETWQAMTDVLNQGLTKSIGVSNF 588
L SLK L V+L+ +H P T ET +A + +G +G+SN+
Sbjct: 94 QLETSLKRLQCPRVDLFYLHMP--------DHSTPVEETLRACHQLHQEGKFMELGLSNY 145
Query: 589 NIQQLEXL----KSXGGVTPSVLQVEINLNLQR--SALLDYCKAQGIXVVAYTPL 735
++ + KS G + P+V Q N ++ + L + G+ A+ PL
Sbjct: 146 AAWEVAEICTLCKSNGWILPTVYQGMYNAITRQVETELFPCLRHFGLRFYAFNPL 200
>AF040639-1|AAD02195.1| 331|Homo sapiens aflatoxin B1-aldehyde
reductase protein.
Length = 331
Score = 34.3 bits (75), Expect = 0.62
Identities = 41/175 (23%), Positives = 76/175 (43%), Gaps = 10/175 (5%)
Frame = +1
Query: 241 IDAGYRHIDTAAIYSTEDQV----GRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLP 408
++ G+ IDTA +YS G ++ ++ VK + + L+ + K +++
Sbjct: 36 LERGHTEIDTAFVYSDGQSETILGGLGLRLGGSDCRVKIDTKAIP--LFGNSLKPDSLRF 93
Query: 409 ALRKSLKNLDLDYVNLYLIHWPIALHENASISQTDYVETWQAMTDVLNQGLTKSIGVSNF 588
L SLK L V+L+ +H P T ET +A + +G +G+SN+
Sbjct: 94 QLETSLKRLQCPRVDLFYLHMP--------DHSTPVEETLRACHQLHQEGKFMELGLSNY 145
Query: 589 NIQQLEXL----KSXGGVTPSVLQVEINLNLQR--SALLDYCKAQGIXVVAYTPL 735
++ + KS G + P+V Q N ++ + L + G+ A+ PL
Sbjct: 146 AAWEVAEICTLCKSNGWILPTVYQGMYNAITRQVETELFPCLRHFGLRFYAFNPL 200
>BC025709-1|AAH25709.1| 331|Homo sapiens aldo-keto reductase family
7, member A3 (aflatoxin aldehyde reductase) protein.
Length = 331
Score = 33.9 bits (74), Expect = 0.82
Identities = 41/175 (23%), Positives = 76/175 (43%), Gaps = 10/175 (5%)
Frame = +1
Query: 241 IDAGYRHIDTAAIYSTEDQV----GRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLP 408
++ G+ IDTA +YS G ++ ++ VK + + L+ + K +++
Sbjct: 36 LERGHTEIDTAFVYSEGQSETILGGLGLRLGGSDCRVKIDTKAIP--LFGNSLKPDSLRF 93
Query: 409 ALRKSLKNLDLDYVNLYLIHWPIALHENASISQTDYVETWQAMTDVLNQGLTKSIGVSNF 588
L SLK L V+L+ +H P T ET +A + +G +G+SN+
Sbjct: 94 QLETSLKRLQCPRVDLFYLHMP--------DHSTPVEETLRACHQLHQEGKFVELGLSNY 145
Query: 589 NIQQLEXL----KSXGGVTPSVLQVEINLNLQR--SALLDYCKAQGIXVVAYTPL 735
++ + KS G + P+V Q N ++ + L + G+ A+ PL
Sbjct: 146 AAWEVAEICTLCKSNGWILPTVYQGMYNAITRQVETELFPCLRHFGLRFYAFNPL 200
>AL035413-11|CAI22232.1| 331|Homo sapiens aldo-keto reductase
family 7, member A3 (aflatoxin aldehyde reductase)
protein.
Length = 331
Score = 33.9 bits (74), Expect = 0.82
Identities = 41/175 (23%), Positives = 76/175 (43%), Gaps = 10/175 (5%)
Frame = +1
Query: 241 IDAGYRHIDTAAIYSTEDQV----GRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLP 408
++ G+ IDTA +YS G ++ ++ VK + + L+ + K +++
Sbjct: 36 LERGHTEIDTAFVYSEGQSETILGGLGLRLGGSDCRVKIDTKAIP--LFGNSLKPDSLRF 93
Query: 409 ALRKSLKNLDLDYVNLYLIHWPIALHENASISQTDYVETWQAMTDVLNQGLTKSIGVSNF 588
L SLK L V+L+ +H P T ET +A + +G +G+SN+
Sbjct: 94 QLETSLKRLQCPRVDLFYLHMP--------DHSTPVEETLRACHQLHQEGKFVELGLSNY 145
Query: 589 NIQQLEXL----KSXGGVTPSVLQVEINLNLQR--SALLDYCKAQGIXVVAYTPL 735
++ + KS G + P+V Q N ++ + L + G+ A+ PL
Sbjct: 146 AAWEVAEICTLCKSNGWILPTVYQGMYNAITRQVETELFPCLRHFGLRFYAFNPL 200
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 129,776,733
Number of Sequences: 237096
Number of extensions: 2704002
Number of successful extensions: 6900
Number of sequences better than 10.0: 133
Number of HSP's better than 10.0 without gapping: 6226
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 6669
length of database: 76,859,062
effective HSP length: 90
effective length of database: 55,520,422
effective search space used: 11714809042
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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