Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BmNP07_FL5_E22
(877 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
AJ306454-1|CAC34819.1| 497|Homo sapiens neuronal nicotinic acet... 65 3e-10
Y08416-1|CAA69693.1| 498|Homo sapiens nicotinic acetylcholine r... 63 1e-09
U62439-1|AAB40117.1| 498|Homo sapiens nicotinic acetylcholine r... 63 1e-09
U48861-1|AAA92123.1| 498|Homo sapiens beta 4 nicotinic acetylch... 63 1e-09
BC096082-1|AAH96082.1| 498|Homo sapiens cholinergic receptor, n... 63 1e-09
BC096080-1|AAH96080.1| 498|Homo sapiens cholinergic receptor, n... 63 1e-09
AF306329-1|AAL02062.1| 498|Homo sapiens neuronal nicotinic acet... 63 1e-09
Y08417-1|CAA69694.1| 458|Homo sapiens nicotinic acetylcholine r... 60 1e-08
X67513-1|CAA47851.1| 423|Homo sapiens nicotinic acetylcholine ... 60 1e-08
U62438-1|AAB40116.1| 458|Homo sapiens nicotinic acetylcholine r... 60 1e-08
BC069788-1|AAH69788.1| 458|Homo sapiens cholinergic receptor, n... 60 1e-08
BC069703-1|AAH69703.1| 458|Homo sapiens cholinergic receptor, n... 60 1e-08
BC069681-1|AAH69681.1| 458|Homo sapiens cholinergic receptor, n... 60 1e-08
AF140765-1|AAD33063.1| 458|Homo sapiens neuronal acetylcholine ... 60 1e-08
X68275-1|CAA48336.1| 451|Homo sapiens nicotinic receptor beta 4... 59 2e-08
BT006897-1|AAP35543.1| 505|Homo sapiens cholinergic receptor, n... 59 2e-08
BT006646-1|AAP35292.1| 489|Homo sapiens cholinergic receptor, n... 59 2e-08
BC006114-1|AAH06114.1| 489|Homo sapiens CHRNA3 protein protein. 59 2e-08
BC002996-1|AAH02996.1| 505|Homo sapiens cholinergic receptor, n... 59 2e-08
BC001642-1|AAH01642.1| 505|Homo sapiens cholinergic receptor, n... 59 2e-08
BC000513-1|AAH00513.1| 505|Homo sapiens cholinergic receptor, n... 59 2e-08
AF385584-1|AAK68110.1| 489|Homo sapiens nicotinic cholinergic r... 59 2e-08
Y08418-1|CAA69695.1| 503|Homo sapiens nicotinic acetylcholine r... 58 4e-08
U62432-1|AAB40110.1| 504|Homo sapiens nicotinic acetylcholine r... 58 4e-08
M37981-1|AAA59942.1| 503|Homo sapiens neuronal nicotinic acetyl... 58 4e-08
BC098443-1|AAH98443.1| 504|Homo sapiens cholinergic receptor, n... 58 4e-08
AJ007783-1|CAA07682.1| 504|Homo sapiens nicotinic acetylcholine... 58 4e-08
Y00762-1|CAA68731.1| 457|Homo sapiens protein ( Human mRNA for ... 57 1e-07
X02502-1|CAA26344.1| 457|Homo sapiens acetylcholine receptor pr... 57 1e-07
S77094-1|AAD14247.1| 457|Homo sapiens nicotinic acetylcholine r... 57 1e-07
BC006314-1|AAH06314.1| 269|Homo sapiens CHRNA1 protein protein. 57 1e-07
AC018890-1|AAY14687.1| 457|Homo sapiens unknown protein. 57 1e-07
X53559-1|CAA37625.1| 474|Homo sapiens neuronal nicotinic acetyl... 56 1e-07
Y16281-1|CAA76154.1| 529|Homo sapiens nicotinic acetylcholine r... 56 2e-07
Y08419-1|CAA69696.1| 468|Homo sapiens nicotinic acetylcholine r... 56 2e-07
X14830-1|CAA32939.1| 501|Homo sapiens protein ( Human mRNA for ... 56 2e-07
U62434-1|AAB40112.1| 468|Homo sapiens nicotinic acetylcholine r... 56 2e-07
U62431-1|AAB40109.1| 529|Homo sapiens nicotinic acetylcholine r... 56 2e-07
BC033639-1|AAH33639.1| 468|Homo sapiens cholinergic receptor, n... 56 2e-07
BC011371-1|AAH11371.1| 501|Homo sapiens cholinergic receptor, n... 56 2e-07
AJ306481-1|CAC34820.1| 468|Homo sapiens neuronal nicotinic acet... 56 2e-07
Y16282-1|CAA76155.1| 494|Homo sapiens nicotinic acetylcholine r... 55 3e-07
U62435-1|AAB40113.1| 494|Homo sapiens nicotinic acetylcholine r... 55 3e-07
BC014456-1|AAH14456.1| 494|Homo sapiens cholinergic receptor, n... 55 3e-07
AB079251-1|BAC06855.1| 494|Homo sapiens Nicotinic acetylcholine... 55 3e-07
M86383-1|AAC84176.1| 502|Homo sapiens nicotinic acetylcholine r... 55 4e-07
M83712-1|AAA58357.1| 468|Homo sapiens nicotinic receptor alpha ... 55 4e-07
Y08421-1|CAA69698.1| 627|Homo sapiens nicotinic acetylcholine r... 54 5e-07
X89741-1|CAA61893.1| 627|Homo sapiens neuronal acetylcholine re... 54 5e-07
U62433-1|AAB40111.1| 627|Homo sapiens nicotinic acetylcholine r... 54 5e-07
L35901-1|AAA64743.1| 627|Homo sapiens nicotinic acetylcholine r... 54 5e-07
DQ093071-1|AAY88737.1| 627|Homo sapiens cholinergic receptor, n... 54 5e-07
BC096290-1|AAH96290.1| 627|Homo sapiens cholinergic receptor, n... 54 5e-07
BC023553-1|AAH23553.1| 501|Homo sapiens cholinergic receptor, n... 54 5e-07
X87629-1|CAA60959.1| 602|Homo sapiens nicotinic acetylcholine r... 54 7e-07
BC111802-1|AAI11803.1| 465|Homo sapiens CHRNG protein protein. 54 9e-07
X01715-1|CAA25861.1| 520|Homo sapiens acetylcholine receptor ga... 52 2e-06
AC092165-3|AAY24103.1| 520|Homo sapiens unknown protein. 52 2e-06
AJ001935-1|CAA05108.1| 504|Homo sapiens CHRNB2 protein. 51 6e-06
Y08415-1|CAA69692.1| 502|Homo sapiens nicotinic acetylcholine r... 50 8e-06
X55019-1|CAA38759.1| 517|Homo sapiens acetylcholine receptor de... 50 8e-06
X53179-1|CAA37320.1| 502|Homo sapiens precursor peptide (AA -25... 50 8e-06
U62437-1|AAB40115.1| 502|Homo sapiens nicotinic acetylcholine r... 50 8e-06
BC093925-1|AAH93925.1| 517|Homo sapiens cholinergic receptor, n... 50 8e-06
BC093923-1|AAH93923.1| 517|Homo sapiens cholinergic receptor, n... 50 8e-06
BC075041-1|AAH75041.1| 502|Homo sapiens cholinergic receptor, n... 50 8e-06
BC075040-1|AAH75040.1| 502|Homo sapiens cholinergic receptor, n... 50 8e-06
AL592078-3|CAI16184.1| 502|Homo sapiens cholinergic receptor, n... 50 8e-06
AF077186-1|AAD45422.1| 502|Homo sapiens neuronal nicotinic acet... 50 8e-06
AC092165-2|AAY24102.1| 517|Homo sapiens unknown protein. 50 8e-06
X66403-1|CAA47030.1| 493|Homo sapiens acetylcholine receptor ep... 50 1e-05
AF105999-1|AAD24503.1| 493|Homo sapiens acetylcholine receptor ... 50 1e-05
AJ295237-1|CAC16144.1| 450|Homo sapiens neuronal nicotinic acet... 48 4e-05
AJ278118-1|CAC20435.1| 450|Homo sapiens neuronal nicotinic acet... 48 4e-05
AF327367-1|AAK14333.1| 450|Homo sapiens nicotinic acetylcholine... 48 4e-05
AF199235-1|AAG00795.2| 450|Homo sapiens nicotinic acetylcholine... 48 4e-05
Z23141-1|CAA80672.1| 479|Homo sapiens cholinergic receptor, nic... 47 8e-05
Y08420-1|CAA69697.1| 502|Homo sapiens nicotinic acetylcholine r... 47 8e-05
X70297-1|CAA49778.1| 502|Homo sapiens neuronal nicotinic acetyl... 47 8e-05
U62436-1|AAB40114.1| 502|Homo sapiens nicotinic acetylcholine r... 47 8e-05
DQ644022-1|ABG35128.1| 456|Homo sapiens 5-HT3 receptor subunit ... 47 8e-05
BC101185-1|AAI01186.1| 374|Homo sapiens HTR3E protein protein. 47 8e-05
BC101183-1|AAI01184.1| 471|Homo sapiens 5-hydroxytryptamine (se... 47 8e-05
BC101182-1|AAI01183.1| 471|Homo sapiens 5-hydroxytryptamine (se... 47 8e-05
AY159813-1|AAO38167.2| 471|Homo sapiens 5-hydroxytryptamine ser... 47 8e-05
AJ586911-1|CAE52911.1| 502|Homo sapiens nicotinic acetylcholine... 47 8e-05
BC096083-1|AAH96083.1| 198|Homo sapiens CHRNB4 protein protein. 47 1e-04
BC096081-1|AAH96081.1| 198|Homo sapiens CHRNB4 protein protein. 47 1e-04
U40583-1|AAA83561.1| 502|Homo sapiens alpha 7 neuronal nicotini... 46 2e-04
BC131799-1|AAI31800.1| 447|Homo sapiens 5-hydroxytryptamine (se... 46 2e-04
AY349353-1|AAQ93477.1| 456|Homo sapiens 5-HT3c1 serotonin recep... 46 2e-04
AY349352-1|AAQ93476.1| 441|Homo sapiens 5-HT3c1 serotonin recep... 46 2e-04
AF385585-1|AAK68111.1| 502|Homo sapiens nicotinic cholinergic r... 46 2e-04
BC110597-1|AAI10598.1| 411|Homo sapiens ligand-gated ion channe... 45 3e-04
AK122638-1|BAC85499.1| 266|Homo sapiens yte protein of 76kDa) (... 45 3e-04
AF512521-1|AAO20969.1| 411|Homo sapiens ligand-gated ion channe... 45 3e-04
AF459285-1|AAL66182.1| 447|Homo sapiens 5-hydroxytryptamine rec... 45 3e-04
AB223030-1|BAE19924.1| 411|Homo sapiens ligand-gated ion-channe... 45 4e-04
L08485-1|AAA58490.1| 462|Homo sapiens GABA-benzodiazepine recep... 44 0.001
BT009830-1|AAP88832.1| 462|Homo sapiens gamma-aminobutyric acid... 44 0.001
BC113575-1|AAI13576.1| 479|Homo sapiens cholinergic receptor, n... 44 0.001
BC113549-1|AAI13550.1| 479|Homo sapiens cholinergic receptor, n... 44 0.001
BC113422-1|AAI13423.1| 462|Homo sapiens gamma-aminobutyric acid... 44 0.001
BC111979-1|AAI11980.1| 462|Homo sapiens gamma-aminobutyric acid... 44 0.001
AY123244-1|AAM74523.1| 479|Homo sapiens nicotinic acetylcholine... 44 0.001
AJ243342-1|CAB65091.1| 479|Homo sapiens nicotinic acetylcholine... 44 0.001
AF227732-1|AAF61920.1| 470|Homo sapiens nicotinic acetylcholine... 44 0.001
AC118275-1|AAY40986.1| 479|Homo sapiens unknown protein. 44 0.001
U77731-2|AAB38273.1| 360|Homo sapiens glycine receptor alpha 2B... 43 0.002
S77554-1|AAB33983.1| 474|Homo sapiens GABAA receptor beta 2 sub... 43 0.002
S77553-1|AAB33982.1| 512|Homo sapiens GABAA receptor beta 2 sub... 43 0.002
S67368-1|AAB29370.1| 474|Homo sapiens gamma-aminobutyric acid A... 43 0.002
CR450343-1|CAG29339.1| 452|Homo sapiens GLRA2 protein. 43 0.002
BC105639-1|AAI05640.1| 474|Homo sapiens GABRB2 protein protein. 43 0.002
BC099719-1|AAH99719.1| 474|Homo sapiens GABRB2 protein protein. 43 0.002
BC099705-1|AAH99705.1| 474|Homo sapiens GABRB2 protein protein. 43 0.002
AY437084-1|AAR87843.1| 452|Homo sapiens glycine receptor alpha2... 43 0.002
X52008-1|CAA36257.1| 452|Homo sapiens inhibitory glycine recept... 42 0.002
U77731-1|AAB38272.1| 360|Homo sapiens glycine receptor alpha 2 ... 42 0.002
M59216-1|AAA35862.1| 474|Homo sapiens gamma-aminobutyric acid r... 42 0.002
BC032864-1|AAH32864.1| 452|Homo sapiens glycine receptor, alpha... 42 0.002
BC028629-1|AAH28629.1| 492|Homo sapiens gamma-aminobutyric acid... 42 0.002
AY437083-1|AAR87842.1| 452|Homo sapiens glycine receptor alpha2... 42 0.002
AF053495-1|AAC35290.1| 452|Homo sapiens glycine receptor alpha ... 42 0.002
S62908-1|AAB27279.1| 492|Homo sapiens gamma-aminobutyric acidA ... 42 0.003
AF166361-1|AAG12455.1| 492|Homo sapiens GABA receptor subunit a... 42 0.003
X14767-1|CAA32875.1| 474|Homo sapiens GABA-A receptor beta 1 su... 42 0.004
BC109211-1|AAI09212.1| 632|Homo sapiens gamma-aminobutyric acid... 42 0.004
BC109210-1|AAI09211.1| 632|Homo sapiens gamma-aminobutyric acid... 42 0.004
AF189259-1|AAF70380.1| 632|Homo sapiens GABA-A receptor theta s... 42 0.004
AF144648-1|AAD51172.1| 627|Homo sapiens GABA-A receptor theta p... 42 0.004
BC033801-1|AAH33801.1| 452|Homo sapiens gamma-aminobutyric acid... 41 0.007
AL391845-4|CAI15436.1| 452|Homo sapiens gamma-aminobutyric acid... 41 0.007
AF016917-1|AAB70007.1| 452|Homo sapiens GABA-A receptor delta s... 41 0.007
U30461-1|AAB52519.1| 554|Homo sapiens GABAA receptor subunit al... 39 0.021
BC035055-1|AAH35055.1| 554|Homo sapiens gamma-aminobutyric acid... 39 0.021
U93917-1|AAC39917.1| 449|Homo sapiens glycine receptor alpha 3 ... 39 0.027
BC114947-1|AAI14948.1| 457|Homo sapiens GLRA1 protein protein. 39 0.027
BC074980-1|AAH74980.1| 449|Homo sapiens glycine receptor, alpha... 39 0.027
BC036086-1|AAH36086.1| 464|Homo sapiens glycine receptor, alpha... 39 0.027
AF017724-1|AAC39919.1| 465|Homo sapiens glycine receptor alpha ... 39 0.027
X52009-1|CAA36258.1| 449|Homo sapiens inhibitory glycine recept... 38 0.036
U95367-1|AAC51357.1| 440|Homo sapiens GABA-A receptor pi subuni... 38 0.036
BC109106-1|AAI09107.1| 440|Homo sapiens gamma-aminobutyric acid... 38 0.036
BC109105-1|AAI09106.1| 440|Homo sapiens gamma-aminobutyric acid... 38 0.036
BC074865-1|AAH74865.1| 440|Homo sapiens gamma-aminobutyric acid... 38 0.036
BC074810-1|AAH74810.1| 440|Homo sapiens gamma-aminobutyric acid... 38 0.036
AF009702-1|AAC24194.1| 440|Homo sapiens GABA-A receptor pi subu... 38 0.036
S81944-1|AAB36480.1| 453|Homo sapiens gamma-aminobutyric acid t... 38 0.048
BC099641-1|AAH99641.1| 453|Homo sapiens gamma-aminobutyric acid... 38 0.048
BC099640-1|AAH99640.1| 453|Homo sapiens gamma-aminobutyric acid... 38 0.048
BC096242-1|AAH96242.1| 453|Homo sapiens gamma-aminobutyric acid... 38 0.048
BC096241-1|AAH96241.1| 453|Homo sapiens gamma-aminobutyric acid... 38 0.048
Z93848-1|CAI41994.1| 376|Homo sapiens glycine receptor, alpha 4... 37 0.083
BC022449-1|AAH22449.1| 474|Homo sapiens gamma-aminobutyric acid... 37 0.083
AL049610-1|CAI42158.1| 376|Homo sapiens glycine receptor, alpha... 37 0.083
BC114967-1|AAI14968.1| 366|Homo sapiens GLRA1 protein protein. 36 0.19
U83981-1|AAC25631.1| 674|Homo sapiens apoptosis associated prot... 31 4.1
CR457259-1|CAG33540.1| 674|Homo sapiens PPP1R15A protein. 31 4.1
BC003067-1|AAH03067.1| 674|Homo sapiens protein phosphatase 1, ... 31 4.1
AK001361-1|BAA91649.1| 674|Homo sapiens protein ( Homo sapiens ... 31 4.1
>AJ306454-1|CAC34819.1| 497|Homo sapiens neuronal nicotinic
acetylcholine receptor beta-4 subunit protein.
Length = 497
Score = 65.3 bits (152), Expect = 3e-10
Identities = 45/165 (27%), Positives = 75/165 (45%), Gaps = 8/165 (4%)
Frame = +1
Query: 64 LLPFLLTCAIASAAECENATSLSLMIDSLL--ATYD---RDSPPDSKIV-VNLTLHLRHA 225
L+ F L A+ C A + ++D LL Y+ R + S+++ + L L L
Sbjct: 7 LVLFFLV-ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQL 65
Query: 226 -NIRESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAXATTX 399
++ E E + L+ W D RL+WN+ + G + + ++R+W PD+VL N T
Sbjct: 66 ISVNEREQIMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNDGTYE 125
Query: 400 GDYALRARVSNNGSVSWIKRLDISXPISMQLDXWXNDMQTCTFKF 534
V +NGSV W+ +++ + D Q CT KF
Sbjct: 126 VSVYTNLIVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKF 170
>Y08416-1|CAA69693.1| 498|Homo sapiens nicotinic acetylcholine
receptor beta4 subunit precursor protein.
Length = 498
Score = 63.3 bits (147), Expect = 1e-09
Identities = 46/166 (27%), Positives = 76/166 (45%), Gaps = 9/166 (5%)
Frame = +1
Query: 64 LLPFLLTCAIASAAECENATSLSLMIDSLL--ATYD---RDSPPDSKIV-VNLTLHLRHA 225
L+ F L A+ C A + ++D LL Y+ R + S+++ + L L L
Sbjct: 7 LVLFFLV-ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQL 65
Query: 226 -NIRESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLN-AXATT 396
++ E E + L+ W D RL+WN+ + G + + ++R+W PD+VL N A T
Sbjct: 66 ISVNEREQIMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNADGTY 125
Query: 397 XGDYALRARVSNNGSVSWIKRLDISXPISMQLDXWXNDMQTCTFKF 534
V +NGSV W+ +++ + D Q CT KF
Sbjct: 126 EVSVYTNLIVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKF 171
>U62439-1|AAB40117.1| 498|Homo sapiens nicotinic acetylcholine
receptor beta4 subunit precursor protein.
Length = 498
Score = 63.3 bits (147), Expect = 1e-09
Identities = 46/166 (27%), Positives = 76/166 (45%), Gaps = 9/166 (5%)
Frame = +1
Query: 64 LLPFLLTCAIASAAECENATSLSLMIDSLL--ATYD---RDSPPDSKIV-VNLTLHLRHA 225
L+ F L A+ C A + ++D LL Y+ R + S+++ + L L L
Sbjct: 7 LVLFFLV-ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQL 65
Query: 226 -NIRESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLN-AXATT 396
++ E E + L+ W D RL+WN+ + G + + ++R+W PD+VL N A T
Sbjct: 66 ISVNEREQIMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNADGTY 125
Query: 397 XGDYALRARVSNNGSVSWIKRLDISXPISMQLDXWXNDMQTCTFKF 534
V +NGSV W+ +++ + D Q CT KF
Sbjct: 126 EVSVYTNLIVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKF 171
>U48861-1|AAA92123.1| 498|Homo sapiens beta 4 nicotinic
acetylcholine receptor subunit protein.
Length = 498
Score = 63.3 bits (147), Expect = 1e-09
Identities = 46/166 (27%), Positives = 76/166 (45%), Gaps = 9/166 (5%)
Frame = +1
Query: 64 LLPFLLTCAIASAAECENATSLSLMIDSLL--ATYD---RDSPPDSKIV-VNLTLHLRHA 225
L+ F L A+ C A + ++D LL Y+ R + S+++ + L L L
Sbjct: 7 LVLFFLV-ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQL 65
Query: 226 -NIRESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLN-AXATT 396
++ E E + L+ W D RL+WN+ + G + + ++R+W PD+VL N A T
Sbjct: 66 ISVNEREQIMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNADGTY 125
Query: 397 XGDYALRARVSNNGSVSWIKRLDISXPISMQLDXWXNDMQTCTFKF 534
V +NGSV W+ +++ + D Q CT KF
Sbjct: 126 EVSVYTNLIVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKF 171
>BC096082-1|AAH96082.1| 498|Homo sapiens cholinergic receptor,
nicotinic, beta 4 protein.
Length = 498
Score = 63.3 bits (147), Expect = 1e-09
Identities = 46/166 (27%), Positives = 76/166 (45%), Gaps = 9/166 (5%)
Frame = +1
Query: 64 LLPFLLTCAIASAAECENATSLSLMIDSLL--ATYD---RDSPPDSKIV-VNLTLHLRHA 225
L+ F L A+ C A + ++D LL Y+ R + S+++ + L L L
Sbjct: 7 LVLFFLV-ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQL 65
Query: 226 -NIRESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLN-AXATT 396
++ E E + L+ W D RL+WN+ + G + + ++R+W PD+VL N A T
Sbjct: 66 ISVNEREQIMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNADGTY 125
Query: 397 XGDYALRARVSNNGSVSWIKRLDISXPISMQLDXWXNDMQTCTFKF 534
V +NGSV W+ +++ + D Q CT KF
Sbjct: 126 EVSVYTNLIVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKF 171
>BC096080-1|AAH96080.1| 498|Homo sapiens cholinergic receptor,
nicotinic, beta 4 protein.
Length = 498
Score = 63.3 bits (147), Expect = 1e-09
Identities = 46/166 (27%), Positives = 76/166 (45%), Gaps = 9/166 (5%)
Frame = +1
Query: 64 LLPFLLTCAIASAAECENATSLSLMIDSLL--ATYD---RDSPPDSKIV-VNLTLHLRHA 225
L+ F L A+ C A + ++D LL Y+ R + S+++ + L L L
Sbjct: 7 LVLFFLV-ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQL 65
Query: 226 -NIRESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLN-AXATT 396
++ E E + L+ W D RL+WN+ + G + + ++R+W PD+VL N A T
Sbjct: 66 ISVNEREQIMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNADGTY 125
Query: 397 XGDYALRARVSNNGSVSWIKRLDISXPISMQLDXWXNDMQTCTFKF 534
V +NGSV W+ +++ + D Q CT KF
Sbjct: 126 EVSVYTNLIVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKF 171
>AF306329-1|AAL02062.1| 498|Homo sapiens neuronal nicotinic
acetylcholine receptor beta 4 subunit protein.
Length = 498
Score = 63.3 bits (147), Expect = 1e-09
Identities = 46/166 (27%), Positives = 76/166 (45%), Gaps = 9/166 (5%)
Frame = +1
Query: 64 LLPFLLTCAIASAAECENATSLSLMIDSLL--ATYD---RDSPPDSKIV-VNLTLHLRHA 225
L+ F L A+ C A + ++D LL Y+ R + S+++ + L L L
Sbjct: 7 LVLFFLV-ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQL 65
Query: 226 -NIRESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLN-AXATT 396
++ E E + L+ W D RL+WN+ + G + + ++R+W PD+VL N A T
Sbjct: 66 ISVNEREQIMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNADGTY 125
Query: 397 XGDYALRARVSNNGSVSWIKRLDISXPISMQLDXWXNDMQTCTFKF 534
V +NGSV W+ +++ + D Q CT KF
Sbjct: 126 EVSVYTNLIVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKF 171
>Y08417-1|CAA69694.1| 458|Homo sapiens nicotinic acetylcholine
receptor beta3 subunit precursor protein.
Length = 458
Score = 60.1 bits (139), Expect = 1e-08
Identities = 32/106 (30%), Positives = 48/106 (45%), Gaps = 2/106 (1%)
Frame = +1
Query: 226 NIRESESTVRIQADLQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLL-NAXATTX 399
++ E + L+ W D +L WN ++G + V SE LW PD+VL NA
Sbjct: 67 DVDEKNQLMTTNVWLKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFE 126
Query: 400 GDYALRARVSNNGSVSWIKRLDISXPISMQLDXWXNDMQTCTFKFG 537
G + V +NG+V W +M + + D Q C+ KFG
Sbjct: 127 GSLMTKVIVKSNGTVVWTPPASYKSSCTMDVTFFPFDRQNCSMKFG 172
>X67513-1|CAA47851.1| 423|Homo sapiens nicotinic acetylcholine
receptor beta-3 subunit protein.
Length = 423
Score = 60.1 bits (139), Expect = 1e-08
Identities = 32/106 (30%), Positives = 48/106 (45%), Gaps = 2/106 (1%)
Frame = +1
Query: 226 NIRESESTVRIQADLQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLL-NAXATTX 399
++ E + L+ W D +L WN ++G + V SE LW PD+VL NA
Sbjct: 32 DVDEKNQLMTTNVWLKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFE 91
Query: 400 GDYALRARVSNNGSVSWIKRLDISXPISMQLDXWXNDMQTCTFKFG 537
G + V +NG+V W +M + + D Q C+ KFG
Sbjct: 92 GSLMTKVIVKSNGTVVWTPPASYKSSCTMDVTFFPFDRQNCSMKFG 137
>U62438-1|AAB40116.1| 458|Homo sapiens nicotinic acetylcholine
receptor beta3 subunit precursor protein.
Length = 458
Score = 60.1 bits (139), Expect = 1e-08
Identities = 32/106 (30%), Positives = 48/106 (45%), Gaps = 2/106 (1%)
Frame = +1
Query: 226 NIRESESTVRIQADLQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLL-NAXATTX 399
++ E + L+ W D +L WN ++G + V SE LW PD+VL NA
Sbjct: 67 DVDEKNQLMTTNVWLKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFE 126
Query: 400 GDYALRARVSNNGSVSWIKRLDISXPISMQLDXWXNDMQTCTFKFG 537
G + V +NG+V W +M + + D Q C+ KFG
Sbjct: 127 GSLMTKVIVKSNGTVVWTPPASYKSSCTMDVTFFPFDRQNCSMKFG 172
>BC069788-1|AAH69788.1| 458|Homo sapiens cholinergic receptor,
nicotinic, beta 3 protein.
Length = 458
Score = 60.1 bits (139), Expect = 1e-08
Identities = 32/106 (30%), Positives = 48/106 (45%), Gaps = 2/106 (1%)
Frame = +1
Query: 226 NIRESESTVRIQADLQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLL-NAXATTX 399
++ E + L+ W D +L WN ++G + V SE LW PD+VL NA
Sbjct: 67 DVDEKNQLMTTNVWLKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFE 126
Query: 400 GDYALRARVSNNGSVSWIKRLDISXPISMQLDXWXNDMQTCTFKFG 537
G + V +NG+V W +M + + D Q C+ KFG
Sbjct: 127 GSLMTKVIVKSNGTVVWTPPASYKSSCTMDVTFFPFDRQNCSMKFG 172
>BC069703-1|AAH69703.1| 458|Homo sapiens cholinergic receptor,
nicotinic, beta 3 protein.
Length = 458
Score = 60.1 bits (139), Expect = 1e-08
Identities = 32/106 (30%), Positives = 48/106 (45%), Gaps = 2/106 (1%)
Frame = +1
Query: 226 NIRESESTVRIQADLQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLL-NAXATTX 399
++ E + L+ W D +L WN ++G + V SE LW PD+VL NA
Sbjct: 67 DVDEKNQLMTTNVWLKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFE 126
Query: 400 GDYALRARVSNNGSVSWIKRLDISXPISMQLDXWXNDMQTCTFKFG 537
G + V +NG+V W +M + + D Q C+ KFG
Sbjct: 127 GSLMTKVIVKSNGTVVWTPPASYKSSCTMDVTFFPFDRQNCSMKFG 172
>BC069681-1|AAH69681.1| 458|Homo sapiens cholinergic receptor,
nicotinic, beta 3 protein.
Length = 458
Score = 60.1 bits (139), Expect = 1e-08
Identities = 32/106 (30%), Positives = 48/106 (45%), Gaps = 2/106 (1%)
Frame = +1
Query: 226 NIRESESTVRIQADLQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLL-NAXATTX 399
++ E + L+ W D +L WN ++G + V SE LW PD+VL NA
Sbjct: 67 DVDEKNQLMTTNVWLKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFE 126
Query: 400 GDYALRARVSNNGSVSWIKRLDISXPISMQLDXWXNDMQTCTFKFG 537
G + V +NG+V W +M + + D Q C+ KFG
Sbjct: 127 GSLMTKVIVKSNGTVVWTPPASYKSSCTMDVTFFPFDRQNCSMKFG 172
>AF140765-1|AAD33063.1| 458|Homo sapiens neuronal acetylcholine
receptor beta-3 subunit precursor protein.
Length = 458
Score = 60.1 bits (139), Expect = 1e-08
Identities = 32/106 (30%), Positives = 48/106 (45%), Gaps = 2/106 (1%)
Frame = +1
Query: 226 NIRESESTVRIQADLQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLL-NAXATTX 399
++ E + L+ W D +L WN ++G + V SE LW PD+VL NA
Sbjct: 67 DVDEKNQLMTTNVWLKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFE 126
Query: 400 GDYALRARVSNNGSVSWIKRLDISXPISMQLDXWXNDMQTCTFKFG 537
G + V +NG+V W +M + + D Q C+ KFG
Sbjct: 127 GSLMTKVIVKSNGTVVWTPPASYKSSCTMDVTFFPFDRQNCSMKFG 172
>X68275-1|CAA48336.1| 451|Homo sapiens nicotinic receptor beta 4
subunit protein.
Length = 451
Score = 58.8 bits (136), Expect = 2e-08
Identities = 34/118 (28%), Positives = 55/118 (46%), Gaps = 3/118 (2%)
Frame = +1
Query: 190 IVVNLTLHLRHA-NIRESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 363
I + L L L ++ E + + L+ W D RL+WN+ + G + + ++R+W P
Sbjct: 7 ISIKLQLSLAQLISVNERDEIMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLP 66
Query: 364 DVVLLN-AXATTXGDYALRARVSNNGSVSWIKRLDISXPISMQLDXWXNDMQTCTFKF 534
D+VL N A T V +NGSV W+ +++ + D Q CT KF
Sbjct: 67 DIVLYNNADGTYEVSVYTNLIVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKF 124
>BT006897-1|AAP35543.1| 505|Homo sapiens cholinergic receptor,
nicotinic, alpha polypeptide 3 protein.
Length = 505
Score = 58.8 bits (136), Expect = 2e-08
Identities = 41/170 (24%), Positives = 76/170 (44%), Gaps = 5/170 (2%)
Frame = +1
Query: 43 MSTTYIILLPFLLTCAIASAAECENATSLSLMID--SLLATYDRDSPPDSKIVVNLTLHL 216
+S ++LL L +A A+E E+ L D ++ S P ++++ + +
Sbjct: 12 LSPPRLLLLLLLSLLPVARASEAEHRLFERLFEDYNEIIRPVANVSDP---VIIHFEVSM 68
Query: 217 RH-ANIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AX 387
+ E + L+ W D +L WN ++G + ++ V ++++W+PD+VL N A
Sbjct: 69 SQLVKVDEVNQIMETNLWLKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAV 128
Query: 388 ATTXGDYALRARVSNNGSVSWIKRLDISXPISMQLDXWXNDMQTCTFKFG 537
D +A + G V+WI + + + D Q CT KFG
Sbjct: 129 GDFQVDDKTKALLKYTGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFG 178
>BT006646-1|AAP35292.1| 489|Homo sapiens cholinergic receptor,
nicotinic, alpha polypeptide 3 protein.
Length = 489
Score = 58.8 bits (136), Expect = 2e-08
Identities = 41/170 (24%), Positives = 76/170 (44%), Gaps = 5/170 (2%)
Frame = +1
Query: 43 MSTTYIILLPFLLTCAIASAAECENATSLSLMID--SLLATYDRDSPPDSKIVVNLTLHL 216
+S ++LL L +A A+E E+ L D ++ S P ++++ + +
Sbjct: 12 LSPPRLLLLLLLSLLPVARASEAEHRLFERLFEDYNEIIRPVANVSDP---VIIHFEVSM 68
Query: 217 RH-ANIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AX 387
+ E + L+ W D +L WN ++G + ++ V ++++W+PD+VL N A
Sbjct: 69 SQLVKVDEVNQIMETNLWLKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAV 128
Query: 388 ATTXGDYALRARVSNNGSVSWIKRLDISXPISMQLDXWXNDMQTCTFKFG 537
D +A + G V+WI + + + D Q CT KFG
Sbjct: 129 GDFQVDDKTKALLKYTGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFG 178
>BC006114-1|AAH06114.1| 489|Homo sapiens CHRNA3 protein protein.
Length = 489
Score = 58.8 bits (136), Expect = 2e-08
Identities = 41/170 (24%), Positives = 76/170 (44%), Gaps = 5/170 (2%)
Frame = +1
Query: 43 MSTTYIILLPFLLTCAIASAAECENATSLSLMID--SLLATYDRDSPPDSKIVVNLTLHL 216
+S ++LL L +A A+E E+ L D ++ S P ++++ + +
Sbjct: 12 LSPPRLLLLLLLSLLPVARASEAEHRLFERLFEDYNEIIRPVANVSDP---VIIHFEVSM 68
Query: 217 RH-ANIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AX 387
+ E + L+ W D +L WN ++G + ++ V ++++W+PD+VL N A
Sbjct: 69 SQLVKVDEVNQIMETNLWLKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAV 128
Query: 388 ATTXGDYALRARVSNNGSVSWIKRLDISXPISMQLDXWXNDMQTCTFKFG 537
D +A + G V+WI + + + D Q CT KFG
Sbjct: 129 GDFQVDDKTKALLKYTGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFG 178
>BC002996-1|AAH02996.1| 505|Homo sapiens cholinergic receptor,
nicotinic, alpha 3 protein.
Length = 505
Score = 58.8 bits (136), Expect = 2e-08
Identities = 41/170 (24%), Positives = 76/170 (44%), Gaps = 5/170 (2%)
Frame = +1
Query: 43 MSTTYIILLPFLLTCAIASAAECENATSLSLMID--SLLATYDRDSPPDSKIVVNLTLHL 216
+S ++LL L +A A+E E+ L D ++ S P ++++ + +
Sbjct: 12 LSPPRLLLLLLLSLLPVARASEAEHRLFERLFEDYNEIIRPVANVSDP---VIIHFEVSM 68
Query: 217 RH-ANIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AX 387
+ E + L+ W D +L WN ++G + ++ V ++++W+PD+VL N A
Sbjct: 69 SQLVKVDEVNQIMETNLWLKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAV 128
Query: 388 ATTXGDYALRARVSNNGSVSWIKRLDISXPISMQLDXWXNDMQTCTFKFG 537
D +A + G V+WI + + + D Q CT KFG
Sbjct: 129 GDFQVDDKTKALLKYTGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFG 178
>BC001642-1|AAH01642.1| 505|Homo sapiens cholinergic receptor,
nicotinic, alpha 3 protein.
Length = 505
Score = 58.8 bits (136), Expect = 2e-08
Identities = 41/170 (24%), Positives = 76/170 (44%), Gaps = 5/170 (2%)
Frame = +1
Query: 43 MSTTYIILLPFLLTCAIASAAECENATSLSLMID--SLLATYDRDSPPDSKIVVNLTLHL 216
+S ++LL L +A A+E E+ L D ++ S P ++++ + +
Sbjct: 12 LSPPRLLLLLLLSLLPVARASEAEHRLFERLFEDYNEIIRPVANVSDP---VIIHFEVSM 68
Query: 217 RH-ANIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AX 387
+ E + L+ W D +L WN ++G + ++ V ++++W+PD+VL N A
Sbjct: 69 SQLVKVDEVNQIMETNLWLKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAV 128
Query: 388 ATTXGDYALRARVSNNGSVSWIKRLDISXPISMQLDXWXNDMQTCTFKFG 537
D +A + G V+WI + + + D Q CT KFG
Sbjct: 129 GDFQVDDKTKALLKYTGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFG 178
>BC000513-1|AAH00513.1| 505|Homo sapiens cholinergic receptor,
nicotinic, alpha 3 protein.
Length = 505
Score = 58.8 bits (136), Expect = 2e-08
Identities = 41/170 (24%), Positives = 76/170 (44%), Gaps = 5/170 (2%)
Frame = +1
Query: 43 MSTTYIILLPFLLTCAIASAAECENATSLSLMID--SLLATYDRDSPPDSKIVVNLTLHL 216
+S ++LL L +A A+E E+ L D ++ S P ++++ + +
Sbjct: 12 LSPPRLLLLLLLSLLPVARASEAEHRLFERLFEDYNEIIRPVANVSDP---VIIHFEVSM 68
Query: 217 RH-ANIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AX 387
+ E + L+ W D +L WN ++G + ++ V ++++W+PD+VL N A
Sbjct: 69 SQLVKVDEVNQIMETNLWLKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAV 128
Query: 388 ATTXGDYALRARVSNNGSVSWIKRLDISXPISMQLDXWXNDMQTCTFKFG 537
D +A + G V+WI + + + D Q CT KFG
Sbjct: 129 GDFQVDDKTKALLKYTGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFG 178
>AF385584-1|AAK68110.1| 489|Homo sapiens nicotinic cholinergic
receptor alpha 3 protein.
Length = 489
Score = 58.8 bits (136), Expect = 2e-08
Identities = 41/170 (24%), Positives = 76/170 (44%), Gaps = 5/170 (2%)
Frame = +1
Query: 43 MSTTYIILLPFLLTCAIASAAECENATSLSLMID--SLLATYDRDSPPDSKIVVNLTLHL 216
+S ++LL L +A A+E E+ L D ++ S P ++++ + +
Sbjct: 6 LSPPRLLLLLLLSLLPVARASEAEHRLFERLFEDYNEIIRPVANVSDP---VIIHFEVSM 62
Query: 217 RH-ANIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AX 387
+ E + L+ W D +L WN ++G + ++ V ++++W+PD+VL N A
Sbjct: 63 SQLVKVDEVNQIMETNLWLKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAV 122
Query: 388 ATTXGDYALRARVSNNGSVSWIKRLDISXPISMQLDXWXNDMQTCTFKFG 537
D +A + G V+WI + + + D Q CT KFG
Sbjct: 123 GDFQVDDKTKALLKYTGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFG 172
>Y08418-1|CAA69695.1| 503|Homo sapiens nicotinic acetylcholine
receptor alpha3 subunit precursor protein.
Length = 503
Score = 58.0 bits (134), Expect = 4e-08
Identities = 41/163 (25%), Positives = 73/163 (44%), Gaps = 3/163 (1%)
Frame = +1
Query: 58 IILLPFLLTCAIASAAECENATSLSLMIDSLLATYDRDSPPDSKIVVNLTLHLRH-ANIR 234
++LL LL A AS AE L + ++ S P ++++ + + +
Sbjct: 17 LLLLLSLLPVARASEAEHRLFERLFEDYNEIIRPVANVSDP---VIIHFEVSMSQLVKVD 73
Query: 235 ESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AXATTXGDY 408
E + L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D
Sbjct: 74 EVNQIMETNLWLKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDD 133
Query: 409 ALRARVSNNGSVSWIKRLDISXPISMQLDXWXNDMQTCTFKFG 537
+A + G V+WI + + + D Q CT KFG
Sbjct: 134 KTKALLKYTGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFG 176
>U62432-1|AAB40110.1| 504|Homo sapiens nicotinic acetylcholine
receptor alpha3 subunit precursor protein.
Length = 504
Score = 58.0 bits (134), Expect = 4e-08
Identities = 41/163 (25%), Positives = 73/163 (44%), Gaps = 3/163 (1%)
Frame = +1
Query: 58 IILLPFLLTCAIASAAECENATSLSLMIDSLLATYDRDSPPDSKIVVNLTLHLRH-ANIR 234
++LL LL A AS AE L + ++ S P ++++ + + +
Sbjct: 18 LLLLLSLLPVARASEAEHRLFERLFEDYNEIIRPVANVSDP---VIIHFEVSMSQLVKVD 74
Query: 235 ESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AXATTXGDY 408
E + L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D
Sbjct: 75 EVNQIMETNLWLKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDD 134
Query: 409 ALRARVSNNGSVSWIKRLDISXPISMQLDXWXNDMQTCTFKFG 537
+A + G V+WI + + + D Q CT KFG
Sbjct: 135 KTKALLKYTGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFG 177
>M37981-1|AAA59942.1| 503|Homo sapiens neuronal nicotinic
acetylcholine receptor protein.
Length = 503
Score = 58.0 bits (134), Expect = 4e-08
Identities = 41/163 (25%), Positives = 73/163 (44%), Gaps = 3/163 (1%)
Frame = +1
Query: 58 IILLPFLLTCAIASAAECENATSLSLMIDSLLATYDRDSPPDSKIVVNLTLHLRH-ANIR 234
++LL LL A AS AE L + ++ S P ++++ + + +
Sbjct: 17 LLLLLSLLPVARASEAEHRLFERLFEDYNEIIRPVANVSDP---VIIHFEVSMSQLVKVD 73
Query: 235 ESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AXATTXGDY 408
E + L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D
Sbjct: 74 EVNQIMETNLWLKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDD 133
Query: 409 ALRARVSNNGSVSWIKRLDISXPISMQLDXWXNDMQTCTFKFG 537
+A + G V+WI + + + D Q CT KFG
Sbjct: 134 KTKALLKYTGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFG 176
>BC098443-1|AAH98443.1| 504|Homo sapiens cholinergic receptor,
nicotinic, alpha 3 protein.
Length = 504
Score = 58.0 bits (134), Expect = 4e-08
Identities = 41/163 (25%), Positives = 73/163 (44%), Gaps = 3/163 (1%)
Frame = +1
Query: 58 IILLPFLLTCAIASAAECENATSLSLMIDSLLATYDRDSPPDSKIVVNLTLHLRH-ANIR 234
++LL LL A AS AE L + ++ S P ++++ + + +
Sbjct: 18 LLLLLSLLPVARASEAEHRLFERLFEDYNEIIRPVANVSDP---VIIHFEVSMSQLVKVD 74
Query: 235 ESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AXATTXGDY 408
E + L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D
Sbjct: 75 EVNQIMETNLWLKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDD 134
Query: 409 ALRARVSNNGSVSWIKRLDISXPISMQLDXWXNDMQTCTFKFG 537
+A + G V+WI + + + D Q CT KFG
Sbjct: 135 KTKALLKYTGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFG 177
>AJ007783-1|CAA07682.1| 504|Homo sapiens nicotinic acetylcholine
receptor alpha-3 subunit protein.
Length = 504
Score = 58.0 bits (134), Expect = 4e-08
Identities = 41/163 (25%), Positives = 73/163 (44%), Gaps = 3/163 (1%)
Frame = +1
Query: 58 IILLPFLLTCAIASAAECENATSLSLMIDSLLATYDRDSPPDSKIVVNLTLHLRH-ANIR 234
++LL LL A AS AE L + ++ S P ++++ + + +
Sbjct: 18 LLLLLSLLPVARASEAEHRLFERLFEDYNEIIRPVANVSDP---VIIHFEVSMSQLVKVD 74
Query: 235 ESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AXATTXGDY 408
E + L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D
Sbjct: 75 EVNQIMETNLWLKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDD 134
Query: 409 ALRARVSNNGSVSWIKRLDISXPISMQLDXWXNDMQTCTFKFG 537
+A + G V+WI + + + D Q CT KFG
Sbjct: 135 KTKALLKYTGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFG 177
>Y00762-1|CAA68731.1| 457|Homo sapiens protein ( Human mRNA for
muscle acetylcholine receptor alpha-subunit. ).
Length = 457
Score = 56.8 bits (131), Expect = 1e-07
Identities = 42/166 (25%), Positives = 72/166 (43%), Gaps = 10/166 (6%)
Frame = +1
Query: 70 PFLLTCAIASAAECENATSLSLMIDSLLATYDRDSPP--DSKIVVNLTLHLRHA---NIR 234
P LL ++ SA + + ++ L Y P D + VV +T+ L+ N+
Sbjct: 5 PLLLLFSLCSAGLVLGSEHETRLVAKLFKDYSSVVRPVEDHRQVVEVTVGLQLIQLINVD 64
Query: 235 ESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAXATTXGDYA 411
E V L+ W+D L WN ++G + + SE++WRPD+VL N GD+A
Sbjct: 65 EVNQIVTTNVRLKQQWVDYNLKWNPDDYGGVKKIHIPSEKIWRPDLVLYN---NADGDFA 121
Query: 412 L----RARVSNNGSVSWIKRLDISXPISMQLDXWXNDMQTCTFKFG 537
+ + + G ++W + + + D Q C+ K G
Sbjct: 122 IVKFTKVLLQYTGHITWTPPAIFKSYCEIIVTHFPFDEQNCSMKLG 167
>X02502-1|CAA26344.1| 457|Homo sapiens acetylcholine receptor
protein.
Length = 457
Score = 56.8 bits (131), Expect = 1e-07
Identities = 42/166 (25%), Positives = 72/166 (43%), Gaps = 10/166 (6%)
Frame = +1
Query: 70 PFLLTCAIASAAECENATSLSLMIDSLLATYDRDSPP--DSKIVVNLTLHLRHA---NIR 234
P LL ++ SA + + ++ L Y P D + VV +T+ L+ N+
Sbjct: 5 PLLLLFSLCSAGLVLGSEHETRLVAKLFKDYSSVVRPVEDHRQVVEVTVGLQLIQLINVD 64
Query: 235 ESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAXATTXGDYA 411
E V L+ W+D L WN ++G + + SE++WRPD+VL N GD+A
Sbjct: 65 EVNQIVTTNVRLKQQWVDYNLKWNPDDYGGVKKIHIPSEKIWRPDLVLYN---NADGDFA 121
Query: 412 L----RARVSNNGSVSWIKRLDISXPISMQLDXWXNDMQTCTFKFG 537
+ + + G ++W + + + D Q C+ K G
Sbjct: 122 IVKFTKVLLQYTGHITWTPPAIFKSYCEIIVTHFPFDEQNCSMKLG 167
>S77094-1|AAD14247.1| 457|Homo sapiens nicotinic acetylcholine
receptor alpha subunit|AChR protein.
Length = 457
Score = 56.8 bits (131), Expect = 1e-07
Identities = 42/166 (25%), Positives = 72/166 (43%), Gaps = 10/166 (6%)
Frame = +1
Query: 70 PFLLTCAIASAAECENATSLSLMIDSLLATYDRDSPP--DSKIVVNLTLHLRHA---NIR 234
P LL ++ SA + + ++ L Y P D + VV +T+ L+ N+
Sbjct: 5 PLLLLFSLCSAGLVLGSEHETRLVAKLFKDYSSVVRPVEDHRQVVEVTVGLQLIQLINVD 64
Query: 235 ESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAXATTXGDYA 411
E V L+ W+D L WN ++G + + SE++WRPD+VL N GD+A
Sbjct: 65 EVNQIVTTNVRLKQQWVDYNLKWNPDDYGGVKKIHIPSEKIWRPDLVLYN---NADGDFA 121
Query: 412 L----RARVSNNGSVSWIKRLDISXPISMQLDXWXNDMQTCTFKFG 537
+ + + G ++W + + + D Q C+ K G
Sbjct: 122 IVKFTKVLLQYTGHITWTPPAIFKSYCEIIVTHFPFDEQNCSMKLG 167
>BC006314-1|AAH06314.1| 269|Homo sapiens CHRNA1 protein protein.
Length = 269
Score = 56.8 bits (131), Expect = 1e-07
Identities = 42/166 (25%), Positives = 72/166 (43%), Gaps = 10/166 (6%)
Frame = +1
Query: 70 PFLLTCAIASAAECENATSLSLMIDSLLATYDRDSPP--DSKIVVNLTLHLRHA---NIR 234
P LL ++ SA + + ++ L Y P D + VV +T+ L+ N+
Sbjct: 5 PLLLLFSLCSAGLVLGSEHETRLVAKLFKDYSSVVRPVEDHRQVVEVTVGLQLIQLINVD 64
Query: 235 ESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAXATTXGDYA 411
E V L+ W+D L WN ++G + + SE++WRPD+VL N GD+A
Sbjct: 65 EVNQIVTTNVRLKQQWVDYNLKWNPDDYGGVKKIHIPSEKIWRPDLVLYN---NADGDFA 121
Query: 412 L----RARVSNNGSVSWIKRLDISXPISMQLDXWXNDMQTCTFKFG 537
+ + + G ++W + + + D Q C+ K G
Sbjct: 122 IVKFTKVLLQYTGHITWTPPAIFKSYCEIIVTHFPFDEQNCSMKLG 167
>AC018890-1|AAY14687.1| 457|Homo sapiens unknown protein.
Length = 457
Score = 56.8 bits (131), Expect = 1e-07
Identities = 42/166 (25%), Positives = 72/166 (43%), Gaps = 10/166 (6%)
Frame = +1
Query: 70 PFLLTCAIASAAECENATSLSLMIDSLLATYDRDSPP--DSKIVVNLTLHLRHA---NIR 234
P LL ++ SA + + ++ L Y P D + VV +T+ L+ N+
Sbjct: 5 PLLLLFSLCSAGLVLGSEHETRLVAKLFKDYSSVVRPVEDHRQVVEVTVGLQLIQLINVD 64
Query: 235 ESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAXATTXGDYA 411
E V L+ W+D L WN ++G + + SE++WRPD+VL N GD+A
Sbjct: 65 EVNQIVTTNVRLKQQWVDYNLKWNPDDYGGVKKIHIPSEKIWRPDLVLYN---NADGDFA 121
Query: 412 L----RARVSNNGSVSWIKRLDISXPISMQLDXWXNDMQTCTFKFG 537
+ + + G ++W + + + D Q C+ K G
Sbjct: 122 IVKFTKVLLQYTGHITWTPPAIFKSYCEIIVTHFPFDEQNCSMKLG 167
>X53559-1|CAA37625.1| 474|Homo sapiens neuronal nicotinic
acetylcholine receptor alpha-3merase protein.
Length = 474
Score = 56.4 bits (130), Expect = 1e-07
Identities = 28/92 (30%), Positives = 47/92 (51%), Gaps = 2/92 (2%)
Frame = +1
Query: 268 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AXATTXGDYALRARVSNNGS 441
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 56 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 115
Query: 442 VSWIKRLDISXPISMQLDXWXNDMQTCTFKFG 537
V+WI + + + D Q CT KFG
Sbjct: 116 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFG 147
>Y16281-1|CAA76154.1| 529|Homo sapiens nicotinic acetylcholine
receptor alpha2 subunit precursor protein.
Length = 529
Score = 56.0 bits (129), Expect = 2e-07
Identities = 31/106 (29%), Positives = 49/106 (46%), Gaps = 2/106 (1%)
Frame = +1
Query: 226 NIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AXATTX 399
++ E + L+ W D +L WN ++G T L V SE +W PD+VL N A
Sbjct: 97 DVDEKNQMMTTNVWLKQEWSDYKLRWNPADFGNITSLRVPSEMIWIPDIVLYNNADGEFA 156
Query: 400 GDYALRARVSNNGSVSWIKRLDISXPISMQLDXWXNDMQTCTFKFG 537
+ +A + + G+V W+ S+ + + D Q C KFG
Sbjct: 157 VTHMTKAHLFSTGTVHWVPPAIYKSSCSIDVTFFPFDQQNCKMKFG 202
>Y08419-1|CAA69696.1| 468|Homo sapiens nicotinic acetylcholine
receptor alpha5 subunit precursor protein.
Length = 468
Score = 56.0 bits (129), Expect = 2e-07
Identities = 36/141 (25%), Positives = 64/141 (45%), Gaps = 7/141 (4%)
Frame = +1
Query: 136 MIDSLLATYDRDSPP----DSKIVVNLTLHLRH-ANIRESESTVRIQADLQMNWIDKRLS 300
++ L Y+R P + KI + L + ++ E + L+ WID +L
Sbjct: 50 LLKDLFQDYERWVRPVEHLNDKIKIKFGLAISQLVDVDEKNQLMTTNVWLKQEWIDVKLR 109
Query: 301 WNAGEWG-CSTWLVSSERLWRPDVVLL-NAXATTXGDYALRARVSNNGSVSWIKRLDISX 474
WN ++G V S+ +W PD+VL NA G + + + NG+V+W +
Sbjct: 110 WNPDDYGGIKVIRVPSDSVWTPDIVLFDNADGRFEGT-STKTVIRYNGTVTWTPPANYKS 168
Query: 475 PISMQLDXWXNDMQTCTFKFG 537
++ + + D+Q C+ KFG
Sbjct: 169 SCTIDVTFFPFDLQNCSMKFG 189
>X14830-1|CAA32939.1| 501|Homo sapiens protein ( Human mRNA for
muscle acetylcholine receptor beta-subunit. ).
Length = 501
Score = 56.0 bits (129), Expect = 2e-07
Identities = 41/120 (34%), Positives = 60/120 (50%), Gaps = 4/120 (3%)
Frame = +1
Query: 187 KIVVNLTL-HLRHANIRESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWR 360
++ V L L L N ++ E + ++ DL+ W D RLSW+ E G + +++E +W
Sbjct: 53 RVSVGLILAQLISLNEKDEEMSTKVYLDLE--WTDYRLSWDPAEHDGIDSLRITAESVWL 110
Query: 361 PDVVLLNAXATTXGDYAL--RARVSNNGSVSWIKRLDISXPISMQLDXWXNDMQTCTFKF 534
PDVVLLN D AL VS++GSV W S+Q+ + D Q CT F
Sbjct: 111 PDVVLLNNNDGNF-DVALDISVVVSSDGSVRWQPPGIYRSSCSIQVTYFPFDWQNCTMVF 169
>U62434-1|AAB40112.1| 468|Homo sapiens nicotinic acetylcholine
receptor alpha5 subunit precursor protein.
Length = 468
Score = 56.0 bits (129), Expect = 2e-07
Identities = 36/141 (25%), Positives = 64/141 (45%), Gaps = 7/141 (4%)
Frame = +1
Query: 136 MIDSLLATYDRDSPP----DSKIVVNLTLHLRH-ANIRESESTVRIQADLQMNWIDKRLS 300
++ L Y+R P + KI + L + ++ E + L+ WID +L
Sbjct: 50 LLKDLFQDYERWVRPVEHLNDKIKIKFGLAISQLVDVDEKNQLMTTNVWLKQEWIDVKLR 109
Query: 301 WNAGEWG-CSTWLVSSERLWRPDVVLL-NAXATTXGDYALRARVSNNGSVSWIKRLDISX 474
WN ++G V S+ +W PD+VL NA G + + + NG+V+W +
Sbjct: 110 WNPDDYGGIKVIRVPSDSVWTPDIVLFDNADGRFEGT-STKTVIRYNGTVTWTPPANYKS 168
Query: 475 PISMQLDXWXNDMQTCTFKFG 537
++ + + D+Q C+ KFG
Sbjct: 169 SCTIDVTFFPFDLQNCSMKFG 189
>U62431-1|AAB40109.1| 529|Homo sapiens nicotinic acetylcholine
receptor alpha2 subunit precursor protein.
Length = 529
Score = 56.0 bits (129), Expect = 2e-07
Identities = 31/106 (29%), Positives = 49/106 (46%), Gaps = 2/106 (1%)
Frame = +1
Query: 226 NIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AXATTX 399
++ E + L+ W D +L WN ++G T L V SE +W PD+VL N A
Sbjct: 97 DVDEKNQMMTTNVWLKQEWSDYKLRWNPADFGNITSLRVPSEMIWIPDIVLYNNADGEFA 156
Query: 400 GDYALRARVSNNGSVSWIKRLDISXPISMQLDXWXNDMQTCTFKFG 537
+ +A + + G+V W+ S+ + + D Q C KFG
Sbjct: 157 VTHMTKAHLFSTGTVHWVPPAIYKSSCSIDVTFFPFDQQNCKMKFG 202
>BC033639-1|AAH33639.1| 468|Homo sapiens cholinergic receptor,
nicotinic, alpha 5 protein.
Length = 468
Score = 56.0 bits (129), Expect = 2e-07
Identities = 36/141 (25%), Positives = 64/141 (45%), Gaps = 7/141 (4%)
Frame = +1
Query: 136 MIDSLLATYDRDSPP----DSKIVVNLTLHLRH-ANIRESESTVRIQADLQMNWIDKRLS 300
++ L Y+R P + KI + L + ++ E + L+ WID +L
Sbjct: 50 LLKDLFQDYERWVRPVEHLNDKIKIKFGLAISQLVDVDEKNQLMTTNVWLKQEWIDVKLR 109
Query: 301 WNAGEWG-CSTWLVSSERLWRPDVVLL-NAXATTXGDYALRARVSNNGSVSWIKRLDISX 474
WN ++G V S+ +W PD+VL NA G + + + NG+V+W +
Sbjct: 110 WNPDDYGGIKVIRVPSDSVWTPDIVLFDNADGRFEGT-STKTVIRYNGTVTWTPPANYKS 168
Query: 475 PISMQLDXWXNDMQTCTFKFG 537
++ + + D+Q C+ KFG
Sbjct: 169 SCTIDVTFFPFDLQNCSMKFG 189
>BC011371-1|AAH11371.1| 501|Homo sapiens cholinergic receptor,
nicotinic, beta 1 (muscle) protein.
Length = 501
Score = 56.0 bits (129), Expect = 2e-07
Identities = 41/120 (34%), Positives = 60/120 (50%), Gaps = 4/120 (3%)
Frame = +1
Query: 187 KIVVNLTL-HLRHANIRESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWR 360
++ V L L L N ++ E + ++ DL+ W D RLSW+ E G + +++E +W
Sbjct: 53 RVSVGLILAQLISLNEKDEEMSTKVYLDLE--WTDYRLSWDPAEHDGIDSLRITAESVWL 110
Query: 361 PDVVLLNAXATTXGDYAL--RARVSNNGSVSWIKRLDISXPISMQLDXWXNDMQTCTFKF 534
PDVVLLN D AL VS++GSV W S+Q+ + D Q CT F
Sbjct: 111 PDVVLLNNNDGNF-DVALDISVVVSSDGSVRWQPPGIYRSSCSIQVTYFPFDWQNCTMVF 169
>AJ306481-1|CAC34820.1| 468|Homo sapiens neuronal nicotinic
acetylcholine receptor alpha-5subunit protein.
Length = 468
Score = 56.0 bits (129), Expect = 2e-07
Identities = 36/141 (25%), Positives = 64/141 (45%), Gaps = 7/141 (4%)
Frame = +1
Query: 136 MIDSLLATYDRDSPP----DSKIVVNLTLHLRH-ANIRESESTVRIQADLQMNWIDKRLS 300
++ L Y+R P + KI + L + ++ E + L+ WID +L
Sbjct: 50 LLKDLFQDYERWVRPVEHLNDKIKIKFGLAISQLVDVDEKNQLMTTNVWLKQEWIDVKLR 109
Query: 301 WNAGEWG-CSTWLVSSERLWRPDVVLL-NAXATTXGDYALRARVSNNGSVSWIKRLDISX 474
WN ++G V S+ +W PD+VL NA G + + + NG+V+W +
Sbjct: 110 WNPDDYGGIKVIRVPSDSVWTPDIVLFDNADGRFEGT-STKTVIRYNGTVTWTPPANYKS 168
Query: 475 PISMQLDXWXNDMQTCTFKFG 537
++ + + D+Q C+ KFG
Sbjct: 169 SCTIDVTFFPFDLQNCSMKFG 189
>Y16282-1|CAA76155.1| 494|Homo sapiens nicotinic acetylcholine
receptor alpha6 subunit precursor protein.
Length = 494
Score = 55.2 bits (127), Expect = 3e-07
Identities = 36/150 (24%), Positives = 65/150 (43%), Gaps = 7/150 (4%)
Frame = +1
Query: 109 CENATSLSLMIDSLLATYDRDSPPDSKIVVNLTLHL-----RHANIRESESTVRIQADLQ 273
C + + L + Y++ P + +T+H + AN+ E + L+
Sbjct: 28 CVGCATEERLFHKLFSHYNQFIRPVENVSDPVTVHFEVAITQLANVDEVNQIMETNLWLR 87
Query: 274 MNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLL-NAXATTXGDYALRARVSNNGSVS 447
W D +L W+ E+ G T V ++++W+PD+VL NA + +A + NG ++
Sbjct: 88 HIWNDYKLRWDPMEYDGIETLRVPADKIWKPDIVLYNNAVGDFQVEGKTKALLKYNGMIT 147
Query: 448 WIKRLDISXPISMQLDXWXNDMQTCTFKFG 537
W M + + D Q C+ KFG
Sbjct: 148 WTPPAIFKSSCPMDITFFPFDHQNCSLKFG 177
>U62435-1|AAB40113.1| 494|Homo sapiens nicotinic acetylcholine
receptor alpha6 subunit precursor protein.
Length = 494
Score = 55.2 bits (127), Expect = 3e-07
Identities = 36/150 (24%), Positives = 65/150 (43%), Gaps = 7/150 (4%)
Frame = +1
Query: 109 CENATSLSLMIDSLLATYDRDSPPDSKIVVNLTLHL-----RHANIRESESTVRIQADLQ 273
C + + L + Y++ P + +T+H + AN+ E + L+
Sbjct: 28 CVGCATEERLFHKLFSHYNQFIRPVENVSDPVTVHFEVAITQLANVDEVNQIMETNLWLR 87
Query: 274 MNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLL-NAXATTXGDYALRARVSNNGSVS 447
W D +L W+ E+ G T V ++++W+PD+VL NA + +A + NG ++
Sbjct: 88 HIWNDYKLRWDPMEYDGIETLRVPADKIWKPDIVLYNNAVGDFQVEGKTKALLKYNGMIT 147
Query: 448 WIKRLDISXPISMQLDXWXNDMQTCTFKFG 537
W M + + D Q C+ KFG
Sbjct: 148 WTPPAIFKSSCPMDITFFPFDHQNCSLKFG 177
>BC014456-1|AAH14456.1| 494|Homo sapiens cholinergic receptor,
nicotinic, alpha 6 protein.
Length = 494
Score = 55.2 bits (127), Expect = 3e-07
Identities = 36/150 (24%), Positives = 65/150 (43%), Gaps = 7/150 (4%)
Frame = +1
Query: 109 CENATSLSLMIDSLLATYDRDSPPDSKIVVNLTLHL-----RHANIRESESTVRIQADLQ 273
C + + L + Y++ P + +T+H + AN+ E + L+
Sbjct: 28 CVGCATEERLFHKLFSHYNQFIRPVENVSDPVTVHFEVAITQLANVDEVNQIMETNLWLR 87
Query: 274 MNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLL-NAXATTXGDYALRARVSNNGSVS 447
W D +L W+ E+ G T V ++++W+PD+VL NA + +A + NG ++
Sbjct: 88 HIWNDYKLRWDPMEYDGIETLRVPADKIWKPDIVLYNNAVGDFQVEGKTKALLKYNGMIT 147
Query: 448 WIKRLDISXPISMQLDXWXNDMQTCTFKFG 537
W M + + D Q C+ KFG
Sbjct: 148 WTPPAIFKSSCPMDITFFPFDHQNCSLKFG 177
>AB079251-1|BAC06855.1| 494|Homo sapiens Nicotinic acetylcholine
receptor alpha 6 protein.
Length = 494
Score = 55.2 bits (127), Expect = 3e-07
Identities = 36/150 (24%), Positives = 65/150 (43%), Gaps = 7/150 (4%)
Frame = +1
Query: 109 CENATSLSLMIDSLLATYDRDSPPDSKIVVNLTLHL-----RHANIRESESTVRIQADLQ 273
C + + L + Y++ P + +T+H + AN+ E + L+
Sbjct: 28 CVGCATEERLFHKLFSHYNQFIRPVENVSDPVTVHFEVAITQLANVDEVNQIMETNLWLR 87
Query: 274 MNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLL-NAXATTXGDYALRARVSNNGSVS 447
W D +L W+ E+ G T V ++++W+PD+VL NA + +A + NG ++
Sbjct: 88 HIWNDYKLRWDPMEYDGIETLRVPADKIWKPDIVLYNNAVGDFQVEGKTKALLKYNGMIT 147
Query: 448 WIKRLDISXPISMQLDXWXNDMQTCTFKFG 537
W M + + D Q C+ KFG
Sbjct: 148 WTPPAIFKSSCPMDITFFPFDHQNCSLKFG 177
>M86383-1|AAC84176.1| 502|Homo sapiens nicotinic acetylcholine
receptor alpha 3 subunit precursor protein.
Length = 502
Score = 54.8 bits (126), Expect = 4e-07
Identities = 41/166 (24%), Positives = 74/166 (44%), Gaps = 6/166 (3%)
Frame = +1
Query: 58 IILLPFLLTCAIASAAECENATSLSLMIDSLLATYDRDSPPDSKIVVNLTLHLRH-ANIR 234
++LL LL A AS AE L + ++ S P ++++ + + +
Sbjct: 16 LLLLLSLLPVARASEAEHRLFERLFEDYNEIIRPVANVSDP---VIIHFEVSMSQLVKVD 72
Query: 235 ESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAXATTXGDYA 411
E + L+ W D +L WN +G + ++ V ++++W+PD+VL N GD+
Sbjct: 73 EVNQIMETNLWLKQIWNDYKLKWNPSGYGGAEFMRVPAQKIWKPDIVLYN---NAVGDFQ 129
Query: 412 L----RARVSNNGSVSWIKRLDISXPISMQLDXWXNDMQTCTFKFG 537
+ +A + G V+WI + + + D Q CT KFG
Sbjct: 130 VTTKTKALLKYTGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFG 175
>M83712-1|AAA58357.1| 468|Homo sapiens nicotinic receptor alpha 5
subunit protein.
Length = 468
Score = 54.8 bits (126), Expect = 4e-07
Identities = 36/141 (25%), Positives = 63/141 (44%), Gaps = 7/141 (4%)
Frame = +1
Query: 136 MIDSLLATYDRDSPP----DSKIVVNLTLHLRH-ANIRESESTVRIQADLQMNWIDKRLS 300
++ L Y+R P + KI + L + ++ E + L+ WID +L
Sbjct: 50 LLKDLFQDYERWVRPVEHLNDKIKIKFGLAISQLVDVDEKNQLMTTNVWLKQEWIDVKLR 109
Query: 301 WNAGEWG-CSTWLVSSERLWRPDVVLL-NAXATTXGDYALRARVSNNGSVSWIKRLDISX 474
WN ++G V S+ W PD+VL NA G + + + NG+V+W +
Sbjct: 110 WNPDDYGGIKVIRVPSDSSWTPDIVLFDNADGRFEGT-STKTVIRYNGTVTWTPPANYKS 168
Query: 475 PISMQLDXWXNDMQTCTFKFG 537
++ + + D+Q C+ KFG
Sbjct: 169 SCTIDVTFFPFDLQNCSMKFG 189
>Y08421-1|CAA69698.1| 627|Homo sapiens nicotinic acetylcholine
receptor alpha4 subunit precursor protein.
Length = 627
Score = 54.4 bits (125), Expect = 5e-07
Identities = 45/169 (26%), Positives = 79/169 (46%), Gaps = 11/169 (6%)
Frame = +1
Query: 64 LLPFLLTCAIASAAECEN-ATSLSLMIDSLLATYDRDSPPDSKI--VVNLTLHLRHA--- 225
LL L T + +++ E A + ++ L + Y++ S P + I VV + L A
Sbjct: 15 LLLLLGTGLLRASSHVETRAHAEERLLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLI 74
Query: 226 NIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAXATTXG 402
++ E + ++ W D +L W+ ++ T + + SE +WRPD+VL N G
Sbjct: 75 DVDEKNQMMTTNVWVKQEWHDYKLRWDPADYENVTSIRIPSELIWRPDIVLYN---NADG 131
Query: 403 DYAL----RARVSNNGSVSWIKRLDISXPISMQLDXWXNDMQTCTFKFG 537
D+A+ +A + ++G V W S+ + + D Q CT KFG
Sbjct: 132 DFAVTHLTKAHLFHDGRVQWTPPAIYKSSCSIDVTFFPFDQQNCTMKFG 180
>X89741-1|CAA61893.1| 627|Homo sapiens neuronal acetylcholine
receptor alpha-4 subunit protein.
Length = 627
Score = 54.4 bits (125), Expect = 5e-07
Identities = 45/169 (26%), Positives = 79/169 (46%), Gaps = 11/169 (6%)
Frame = +1
Query: 64 LLPFLLTCAIASAAECEN-ATSLSLMIDSLLATYDRDSPPDSKI--VVNLTLHLRHA--- 225
LL L T + +++ E A + ++ L + Y++ S P + I VV + L A
Sbjct: 15 LLLLLGTGLLRASSHVETRAHAEERLLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLI 74
Query: 226 NIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAXATTXG 402
++ E + ++ W D +L W+ ++ T + + SE +WRPD+VL N G
Sbjct: 75 DVDEKNQMMTTNVWVKQEWHDYKLRWDPADYENVTSIRIPSELIWRPDIVLYN---NADG 131
Query: 403 DYAL----RARVSNNGSVSWIKRLDISXPISMQLDXWXNDMQTCTFKFG 537
D+A+ +A + ++G V W S+ + + D Q CT KFG
Sbjct: 132 DFAVTHLTKAHLFHDGRVQWTPPAIYKSSCSIDVTFFPFDQQNCTMKFG 180
>U62433-1|AAB40111.1| 627|Homo sapiens nicotinic acetylcholine
receptor alpha4 subunit precursor protein.
Length = 627
Score = 54.4 bits (125), Expect = 5e-07
Identities = 45/169 (26%), Positives = 79/169 (46%), Gaps = 11/169 (6%)
Frame = +1
Query: 64 LLPFLLTCAIASAAECEN-ATSLSLMIDSLLATYDRDSPPDSKI--VVNLTLHLRHA--- 225
LL L T + +++ E A + ++ L + Y++ S P + I VV + L A
Sbjct: 15 LLLLLGTGLLRASSHVETRAHAEERLLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLI 74
Query: 226 NIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAXATTXG 402
++ E + ++ W D +L W+ ++ T + + SE +WRPD+VL N G
Sbjct: 75 DVDEKNQMMTTNVWVKQEWHDYKLRWDPADYENVTSIRIPSELIWRPDIVLYN---NADG 131
Query: 403 DYAL----RARVSNNGSVSWIKRLDISXPISMQLDXWXNDMQTCTFKFG 537
D+A+ +A + ++G V W S+ + + D Q CT KFG
Sbjct: 132 DFAVTHLTKAHLFHDGRVQWTPPAIYKSSCSIDVTFFPFDQQNCTMKFG 180
>L35901-1|AAA64743.1| 627|Homo sapiens nicotinic acetylcholine
receptor alpha 4 subunit protein.
Length = 627
Score = 54.4 bits (125), Expect = 5e-07
Identities = 45/169 (26%), Positives = 79/169 (46%), Gaps = 11/169 (6%)
Frame = +1
Query: 64 LLPFLLTCAIASAAECEN-ATSLSLMIDSLLATYDRDSPPDSKI--VVNLTLHLRHA--- 225
LL L T + +++ E A + ++ L + Y++ S P + I VV + L A
Sbjct: 15 LLLLLGTGLLRASSHVETRAHAEERLLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLI 74
Query: 226 NIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAXATTXG 402
++ E + ++ W D +L W+ ++ T + + SE +WRPD+VL N G
Sbjct: 75 DVDEKNQMMTTNVWVKQEWHDYKLRWDPADYENVTSIRIPSELIWRPDIVLYN---NADG 131
Query: 403 DYAL----RARVSNNGSVSWIKRLDISXPISMQLDXWXNDMQTCTFKFG 537
D+A+ +A + ++G V W S+ + + D Q CT KFG
Sbjct: 132 DFAVTHLTKAHLFHDGRVQWTPPAIYKSSCSIDVTFFPFDQQNCTMKFG 180
>DQ093071-1|AAY88737.1| 627|Homo sapiens cholinergic receptor,
nicotinic, alpha polypeptide 4 protein.
Length = 627
Score = 54.4 bits (125), Expect = 5e-07
Identities = 45/169 (26%), Positives = 79/169 (46%), Gaps = 11/169 (6%)
Frame = +1
Query: 64 LLPFLLTCAIASAAECEN-ATSLSLMIDSLLATYDRDSPPDSKI--VVNLTLHLRHA--- 225
LL L T + +++ E A + ++ L + Y++ S P + I VV + L A
Sbjct: 15 LLLLLGTGLLRASSHVETRAHAEERLLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLI 74
Query: 226 NIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAXATTXG 402
++ E + ++ W D +L W+ ++ T + + SE +WRPD+VL N G
Sbjct: 75 DVDEKNQMMTTNVWVKQEWHDYKLRWDPADYENVTSIRIPSELIWRPDIVLYN---NADG 131
Query: 403 DYAL----RARVSNNGSVSWIKRLDISXPISMQLDXWXNDMQTCTFKFG 537
D+A+ +A + ++G V W S+ + + D Q CT KFG
Sbjct: 132 DFAVTHLTKAHLFHDGRVQWTPPAIYKSSCSIDVTFFPFDQQNCTMKFG 180
>BC096290-1|AAH96290.1| 627|Homo sapiens cholinergic receptor,
nicotinic, alpha 4 protein.
Length = 627
Score = 54.4 bits (125), Expect = 5e-07
Identities = 45/169 (26%), Positives = 79/169 (46%), Gaps = 11/169 (6%)
Frame = +1
Query: 64 LLPFLLTCAIASAAECEN-ATSLSLMIDSLLATYDRDSPPDSKI--VVNLTLHLRHA--- 225
LL L T + +++ E A + ++ L + Y++ S P + I VV + L A
Sbjct: 15 LLLLLGTGLLRASSHVETRAHAEERLLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLI 74
Query: 226 NIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAXATTXG 402
++ E + ++ W D +L W+ ++ T + + SE +WRPD+VL N G
Sbjct: 75 DVDEKNQMMTTNVWVKQEWHDYKLRWDPADYENVTSIRIPSELIWRPDIVLYN---NADG 131
Query: 403 DYAL----RARVSNNGSVSWIKRLDISXPISMQLDXWXNDMQTCTFKFG 537
D+A+ +A + ++G V W S+ + + D Q CT KFG
Sbjct: 132 DFAVTHLTKAHLFHDGRVQWTPPAIYKSSCSIDVTFFPFDQQNCTMKFG 180
>BC023553-1|AAH23553.1| 501|Homo sapiens cholinergic receptor,
nicotinic, beta 1 (muscle) protein.
Length = 501
Score = 54.4 bits (125), Expect = 5e-07
Identities = 38/119 (31%), Positives = 58/119 (48%), Gaps = 3/119 (2%)
Frame = +1
Query: 187 KIVVNLTL-HLRHANIRESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWR 360
++ V L L L N ++ E + ++ DL+ W D RLSW+ E G + +++E +W
Sbjct: 53 RVSVGLILAQLISLNEKDEEMSTKVYLDLE--WTDYRLSWDPAEHDGIDSLRITAESVWL 110
Query: 361 PDVVLL-NAXATTXGDYALRARVSNNGSVSWIKRLDISXPISMQLDXWXNDMQTCTFKF 534
PDVVLL N + VS++GSV W S+Q+ + D Q CT F
Sbjct: 111 PDVVLLNNNDGNFYVALDISVVVSSDGSVRWQPPGIYRSSCSIQVTYFPFDWQNCTMVF 169
>X87629-1|CAA60959.1| 602|Homo sapiens nicotinic acetylcholine
receptor protein.
Length = 602
Score = 54.0 bits (124), Expect = 7e-07
Identities = 39/144 (27%), Positives = 68/144 (47%), Gaps = 10/144 (6%)
Frame = +1
Query: 136 MIDSLLATYDRDSPPDSKI--VVNLTLHLRHA---NIRESESTVRIQADLQMNWIDKRLS 300
++ L + Y++ S P + I VV + L A ++ E + ++ W D +L
Sbjct: 15 LLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLR 74
Query: 301 WNAGEWGCSTWL-VSSERLWRPDVVLLNAXATTXGDYAL----RARVSNNGSVSWIKRLD 465
W+ ++ T + + SE +WRPD+VL N GD+A+ +A + ++G V W
Sbjct: 75 WDPADYENVTSIRIPSELIWRPDIVLYN---NADGDFAVTHLTKAHLFHDGRVQWTPPAI 131
Query: 466 ISXPISMQLDXWXNDMQTCTFKFG 537
S+ + + D Q CT KFG
Sbjct: 132 YKSSCSIDVTFFPFDQQNCTMKFG 155
>BC111802-1|AAI11803.1| 465|Homo sapiens CHRNG protein protein.
Length = 465
Score = 53.6 bits (123), Expect = 9e-07
Identities = 37/135 (27%), Positives = 60/135 (44%), Gaps = 7/135 (5%)
Frame = +1
Query: 70 PFLLTCAIASAAECENATSLSLMIDSLLATYDRDSPPDSKI--VVNLTLHLRHANI---R 234
P LL +A + ++ L+ YD + P + VVN++L L N+
Sbjct: 7 PLLLLLLLAVCLGAQGRNQEERLLADLMQNYDPNLRPAERDSDVVNVSLKLTLTNLISLN 66
Query: 235 ESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAXAT-TXGDY 408
E E + ++M W D RL W+ ++ G V S +WRPD+VL N T + +
Sbjct: 67 EREEALTTNVWIEMQWCDYRLRWDPRDYEGLWVLRVPSTMVWRPDIVLENKSQTYSTNEI 126
Query: 409 ALRARVSNNGSVSWI 453
L+ + S+ WI
Sbjct: 127 DLQLSQEDGQSIEWI 141
>X01715-1|CAA25861.1| 520|Homo sapiens acetylcholine receptor gamma
chain precursor protein.
Length = 520
Score = 52.4 bits (120), Expect = 2e-06
Identities = 46/167 (27%), Positives = 72/167 (43%), Gaps = 8/167 (4%)
Frame = +1
Query: 58 IILLPFLLTCAIASAAECENATSLSLMIDSLLATYDRDSPPDSKI--VVNLTLHLRHANI 231
++LL L C + N L+ D L+ YD + P + VVN++L L N+
Sbjct: 8 LLLLLLLAVCLGGTQRNLRNQEE-RLLAD-LMQNYDPNLRPAERDSDVVNVSLKLTLTNL 65
Query: 232 ---RESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAXATTX 399
E E + ++M W D RL W+ ++ G V S +WRPD+VL N
Sbjct: 66 ISLNEREEALTTNVWIEMQWCDYRLRWDPRDYEGLWVLRVPSTMVWRPDIVLEN-NVDGV 124
Query: 400 GDYAL--RARVSNNGSVSWIKRLDISXPISMQLDXWXNDMQTCTFKF 534
+ AL VS +G + W+ S+ + + D Q C+ F
Sbjct: 125 FEVALYCNVLVSPDGCIYWLPPAIFRSACSISVTYFPFDWQNCSLIF 171
>AC092165-3|AAY24103.1| 520|Homo sapiens unknown protein.
Length = 520
Score = 52.4 bits (120), Expect = 2e-06
Identities = 46/167 (27%), Positives = 72/167 (43%), Gaps = 8/167 (4%)
Frame = +1
Query: 58 IILLPFLLTCAIASAAECENATSLSLMIDSLLATYDRDSPPDSKI--VVNLTLHLRHANI 231
++LL L C + N L+ D L+ YD + P + VVN++L L N+
Sbjct: 8 LLLLLLLAVCLGGTQRNLRNQEE-RLLAD-LMQNYDPNLRPAERDSDVVNVSLKLTLTNL 65
Query: 232 ---RESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAXATTX 399
E E + ++M W D RL W+ ++ G V S +WRPD+VL N
Sbjct: 66 ISLNEREEALTTNVWIEMQWCDYRLRWDPRDYEGLWVLRVPSTMVWRPDIVLEN-NVDGV 124
Query: 400 GDYAL--RARVSNNGSVSWIKRLDISXPISMQLDXWXNDMQTCTFKF 534
+ AL VS +G + W+ S+ + + D Q C+ F
Sbjct: 125 FEVALYCNVLVSPDGCIYWLPPAIFRSACSISVTYFPFDWQNCSLIF 171
>AJ001935-1|CAA05108.1| 504|Homo sapiens CHRNB2 protein.
Length = 504
Score = 50.8 bits (116), Expect = 6e-06
Identities = 45/164 (27%), Positives = 69/164 (42%), Gaps = 6/164 (3%)
Frame = +1
Query: 61 ILLPF--LLTCAIASAAECENATSLSLMIDSLLATYDRDSPPDSKIV-VNLTLHLRHA-N 228
+LL F L C+ A+ E L+ S R + S++V V L + L +
Sbjct: 10 LLLGFGLLRLCSGVWGADTEERLVEHLLDPSRYNKLIRPATNGSELVTVQLMVSLAQLIS 69
Query: 229 IRESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLN-AXATTXG 402
+ E E + L W D RL+W E+ + S+ +W PDVVL N A
Sbjct: 70 VHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLPDVVLYNNADGMYEV 129
Query: 403 DYALRARVSNNGSVSWIKRLDISXPISMQLDXWXNDMQTCTFKF 534
+ A VS +GS+ W+ +++ + D Q CT KF
Sbjct: 130 SFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKF 173
>Y08415-1|CAA69692.1| 502|Homo sapiens nicotinic acetylcholine
receptor beta2 subunit precursor protein.
Length = 502
Score = 50.4 bits (115), Expect = 8e-06
Identities = 33/118 (27%), Positives = 51/118 (43%), Gaps = 3/118 (2%)
Frame = +1
Query: 190 IVVNLTLHLRHA-NIRESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 363
+ V L + L ++ E E + L W D RL+W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 364 DVVLLN-AXATTXGDYALRARVSNNGSVSWIKRLDISXPISMQLDXWXNDMQTCTFKF 534
DVVL N A + A VS +GS+ W+ +++ + D Q CT KF
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKF 173
>X55019-1|CAA38759.1| 517|Homo sapiens acetylcholine receptor delta
subunit protein.
Length = 517
Score = 50.4 bits (115), Expect = 8e-06
Identities = 32/121 (26%), Positives = 55/121 (45%), Gaps = 3/121 (2%)
Frame = +1
Query: 181 DSKIVVNLTLHLRHA-NIRESESTVRIQADLQMNWIDKRLSWNAGEWG-CSTWLVSSERL 354
+ + V L L L + +++E E T+ ++ W D RL WNA E+G S + + +
Sbjct: 49 EESVDVALALTLSNLISLKEVEETLTTNVWIEHGWTDNRLKWNAEEFGNISVLRLPPDMV 108
Query: 355 WRPDVVL-LNAXATTXGDYALRARVSNNGSVSWIKRLDISXPISMQLDXWXNDMQTCTFK 531
W P++VL N + Y+ V + G V W+ + + + D Q C+ K
Sbjct: 109 WLPEIVLENNNDGSFQISYSCNVLVYHYGFVYWLPPAIFRSSCPISVTYFPFDWQNCSLK 168
Query: 532 F 534
F
Sbjct: 169 F 169
>X53179-1|CAA37320.1| 502|Homo sapiens precursor peptide (AA -25 to
477) protein.
Length = 502
Score = 50.4 bits (115), Expect = 8e-06
Identities = 33/118 (27%), Positives = 51/118 (43%), Gaps = 3/118 (2%)
Frame = +1
Query: 190 IVVNLTLHLRHA-NIRESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 363
+ V L + L ++ E E + L W D RL+W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 364 DVVLLN-AXATTXGDYALRARVSNNGSVSWIKRLDISXPISMQLDXWXNDMQTCTFKF 534
DVVL N A + A VS +GS+ W+ +++ + D Q CT KF
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKF 173
>U62437-1|AAB40115.1| 502|Homo sapiens nicotinic acetylcholine
receptor beta2 subunit precursor protein.
Length = 502
Score = 50.4 bits (115), Expect = 8e-06
Identities = 33/118 (27%), Positives = 51/118 (43%), Gaps = 3/118 (2%)
Frame = +1
Query: 190 IVVNLTLHLRHA-NIRESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 363
+ V L + L ++ E E + L W D RL+W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 364 DVVLLN-AXATTXGDYALRARVSNNGSVSWIKRLDISXPISMQLDXWXNDMQTCTFKF 534
DVVL N A + A VS +GS+ W+ +++ + D Q CT KF
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKF 173
>BC093925-1|AAH93925.1| 517|Homo sapiens cholinergic receptor,
nicotinic, delta protein.
Length = 517
Score = 50.4 bits (115), Expect = 8e-06
Identities = 32/121 (26%), Positives = 55/121 (45%), Gaps = 3/121 (2%)
Frame = +1
Query: 181 DSKIVVNLTLHLRHA-NIRESESTVRIQADLQMNWIDKRLSWNAGEWG-CSTWLVSSERL 354
+ + V L L L + +++E E T+ ++ W D RL WNA E+G S + + +
Sbjct: 49 EESVDVALALTLSNLISLKEVEETLTTNVWIEHGWTDNRLKWNAEEFGNISVLRLPPDMV 108
Query: 355 WRPDVVL-LNAXATTXGDYALRARVSNNGSVSWIKRLDISXPISMQLDXWXNDMQTCTFK 531
W P++VL N + Y+ V + G V W+ + + + D Q C+ K
Sbjct: 109 WLPEIVLENNNDGSFQISYSCNVLVYHYGFVYWLPPAIFRSSCPISVTYFPFDWQNCSLK 168
Query: 532 F 534
F
Sbjct: 169 F 169
>BC093923-1|AAH93923.1| 517|Homo sapiens cholinergic receptor,
nicotinic, delta protein.
Length = 517
Score = 50.4 bits (115), Expect = 8e-06
Identities = 32/121 (26%), Positives = 55/121 (45%), Gaps = 3/121 (2%)
Frame = +1
Query: 181 DSKIVVNLTLHLRHA-NIRESESTVRIQADLQMNWIDKRLSWNAGEWG-CSTWLVSSERL 354
+ + V L L L + +++E E T+ ++ W D RL WNA E+G S + + +
Sbjct: 49 EESVDVALALTLSNLISLKEVEETLTTNVWIEHGWTDNRLKWNAEEFGNISVLRLPPDMV 108
Query: 355 WRPDVVL-LNAXATTXGDYALRARVSNNGSVSWIKRLDISXPISMQLDXWXNDMQTCTFK 531
W P++VL N + Y+ V + G V W+ + + + D Q C+ K
Sbjct: 109 WLPEIVLENNNDGSFQISYSCNVLVYHYGFVYWLPPAIFRSSCPISVTYFPFDWQNCSLK 168
Query: 532 F 534
F
Sbjct: 169 F 169
>BC075041-1|AAH75041.1| 502|Homo sapiens cholinergic receptor,
nicotinic, beta 2 (neuronal) protein.
Length = 502
Score = 50.4 bits (115), Expect = 8e-06
Identities = 33/118 (27%), Positives = 51/118 (43%), Gaps = 3/118 (2%)
Frame = +1
Query: 190 IVVNLTLHLRHA-NIRESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 363
+ V L + L ++ E E + L W D RL+W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 364 DVVLLN-AXATTXGDYALRARVSNNGSVSWIKRLDISXPISMQLDXWXNDMQTCTFKF 534
DVVL N A + A VS +GS+ W+ +++ + D Q CT KF
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKF 173
>BC075040-1|AAH75040.1| 502|Homo sapiens cholinergic receptor,
nicotinic, beta 2 (neuronal) protein.
Length = 502
Score = 50.4 bits (115), Expect = 8e-06
Identities = 33/118 (27%), Positives = 51/118 (43%), Gaps = 3/118 (2%)
Frame = +1
Query: 190 IVVNLTLHLRHA-NIRESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 363
+ V L + L ++ E E + L W D RL+W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 364 DVVLLN-AXATTXGDYALRARVSNNGSVSWIKRLDISXPISMQLDXWXNDMQTCTFKF 534
DVVL N A + A VS +GS+ W+ +++ + D Q CT KF
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKF 173
>AL592078-3|CAI16184.1| 502|Homo sapiens cholinergic receptor,
nicotinic, beta 2 (neuronal) protein.
Length = 502
Score = 50.4 bits (115), Expect = 8e-06
Identities = 33/118 (27%), Positives = 51/118 (43%), Gaps = 3/118 (2%)
Frame = +1
Query: 190 IVVNLTLHLRHA-NIRESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 363
+ V L + L ++ E E + L W D RL+W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 364 DVVLLN-AXATTXGDYALRARVSNNGSVSWIKRLDISXPISMQLDXWXNDMQTCTFKF 534
DVVL N A + A VS +GS+ W+ +++ + D Q CT KF
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKF 173
>AF077186-1|AAD45422.1| 502|Homo sapiens neuronal nicotinic
acetylcholine receptor beta 2 protein.
Length = 502
Score = 50.4 bits (115), Expect = 8e-06
Identities = 33/118 (27%), Positives = 51/118 (43%), Gaps = 3/118 (2%)
Frame = +1
Query: 190 IVVNLTLHLRHA-NIRESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 363
+ V L + L ++ E E + L W D RL+W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 364 DVVLLN-AXATTXGDYALRARVSNNGSVSWIKRLDISXPISMQLDXWXNDMQTCTFKF 534
DVVL N A + A VS +GS+ W+ +++ + D Q CT KF
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKF 173
>AC092165-2|AAY24102.1| 517|Homo sapiens unknown protein.
Length = 517
Score = 50.4 bits (115), Expect = 8e-06
Identities = 32/121 (26%), Positives = 55/121 (45%), Gaps = 3/121 (2%)
Frame = +1
Query: 181 DSKIVVNLTLHLRHA-NIRESESTVRIQADLQMNWIDKRLSWNAGEWG-CSTWLVSSERL 354
+ + V L L L + +++E E T+ ++ W D RL WNA E+G S + + +
Sbjct: 49 EESVDVALALTLSNLISLKEVEETLTTNVWIEHGWTDNRLKWNAEEFGNISVLRLPPDMV 108
Query: 355 WRPDVVL-LNAXATTXGDYALRARVSNNGSVSWIKRLDISXPISMQLDXWXNDMQTCTFK 531
W P++VL N + Y+ V + G V W+ + + + D Q C+ K
Sbjct: 109 WLPEIVLENNNDGSFQISYSCNVLVYHYGFVYWLPPAIFRSSCPISVTYFPFDWQNCSLK 168
Query: 532 F 534
F
Sbjct: 169 F 169
>X66403-1|CAA47030.1| 493|Homo sapiens acetylcholine receptor
epsilon subunit CHRNE protein.
Length = 493
Score = 50.0 bits (114), Expect = 1e-05
Identities = 31/122 (25%), Positives = 59/122 (48%), Gaps = 3/122 (2%)
Frame = +1
Query: 178 PDSKIVVNLTLHLRHA-NIRESESTVRIQADLQMNWIDKRLSWNAGEWG-CSTWLVSSER 351
P+ + ++L + L + ++ E E T+ + ++W D RL+++ ++G T V SE
Sbjct: 45 PEDTVTISLKVTLTNLISLNEKEETLTTSVWIGIDWQDYRLNYSKDDFGGIETLRVPSEL 104
Query: 352 LWRPDVVLLNAXATTXG-DYALRARVSNNGSVSWIKRLDISXPISMQLDXWXNDMQTCTF 528
+W P++VL N G Y V GSV+W+ ++++ + D Q C+
Sbjct: 105 VWLPEIVLENNIDGQFGVAYDANVLVYEGGSVTWLPPAIYRSVCAVEVTYFPFDWQNCSL 164
Query: 529 KF 534
F
Sbjct: 165 IF 166
>AF105999-1|AAD24503.1| 493|Homo sapiens acetylcholine receptor
epsilon subunit protein.
Length = 493
Score = 50.0 bits (114), Expect = 1e-05
Identities = 31/122 (25%), Positives = 59/122 (48%), Gaps = 3/122 (2%)
Frame = +1
Query: 178 PDSKIVVNLTLHLRHA-NIRESESTVRIQADLQMNWIDKRLSWNAGEWG-CSTWLVSSER 351
P+ + ++L + L + ++ E E T+ + ++W D RL+++ ++G T V SE
Sbjct: 45 PEDTVTISLKVTLTNLISLNEKEETLTTSVWIGIDWQDYRLNYSKDDFGGIETLRVPSEL 104
Query: 352 LWRPDVVLLNAXATTXG-DYALRARVSNNGSVSWIKRLDISXPISMQLDXWXNDMQTCTF 528
+W P++VL N G Y V GSV+W+ ++++ + D Q C+
Sbjct: 105 VWLPEIVLENNIDGQFGVAYDANVLVYEGGSVTWLPPAIYRSVCAVEVTYFPFDWQNCSL 164
Query: 529 KF 534
F
Sbjct: 165 IF 166
>AJ295237-1|CAC16144.1| 450|Homo sapiens neuronal nicotinic
acetylcholine receptor subunit4 protein.
Length = 450
Score = 48.0 bits (109), Expect = 4e-05
Identities = 44/166 (26%), Positives = 68/166 (40%), Gaps = 7/166 (4%)
Frame = +1
Query: 61 ILLPFLLTCAIASAAECENATSLSLMIDSLLATYDRDSPP--DSKIVVNLTLHLRHANI- 231
+LL FLL A E +L L D L A Y P D+ +N+TL + + I
Sbjct: 12 LLLLFLLPAECLGA---EGRLALKLFRD-LFANYTSALRPVADTDQTLNVTLEVTLSQII 67
Query: 232 --RESESTVRIQADLQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLLN-AXATTX 399
E + + ++ W D L W+ +G + S +WRPD+VL N A A
Sbjct: 68 DMDERNQVLTLYLWIRQEWTDAYLRWDPNAYGGLDAIRIPSSLVWRPDIVLYNKADAQPP 127
Query: 400 GDYALRARVSNNGSVSWIKRLDISXPISMQLDXWXNDMQTCTFKFG 537
G + + ++G+V W + + + D Q C FG
Sbjct: 128 GSASTNVVLRHDGAVRWDAPAITRSSCRVDVAAFPFDAQHCGLTFG 173
>AJ278118-1|CAC20435.1| 450|Homo sapiens neuronal nicotinic
acetylcholine alpha10 subunit protein.
Length = 450
Score = 48.0 bits (109), Expect = 4e-05
Identities = 44/166 (26%), Positives = 68/166 (40%), Gaps = 7/166 (4%)
Frame = +1
Query: 61 ILLPFLLTCAIASAAECENATSLSLMIDSLLATYDRDSPP--DSKIVVNLTLHLRHANI- 231
+LL FLL A E +L L D L A Y P D+ +N+TL + + I
Sbjct: 12 LLLLFLLPAECLGA---EGRLALKLFRD-LFANYTSALRPVADTDQTLNVTLEVTLSQII 67
Query: 232 --RESESTVRIQADLQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLLN-AXATTX 399
E + + ++ W D L W+ +G + S +WRPD+VL N A A
Sbjct: 68 DMDERNQVLTLYLWIRQEWTDAYLRWDPNAYGGLDAIRIPSSLVWRPDIVLYNKADAQPP 127
Query: 400 GDYALRARVSNNGSVSWIKRLDISXPISMQLDXWXNDMQTCTFKFG 537
G + + ++G+V W + + + D Q C FG
Sbjct: 128 GSASTNVVLRHDGAVRWDAPAITRSSCRVDVAAFPFDAQHCGLTFG 173
>AF327367-1|AAK14333.1| 450|Homo sapiens nicotinic acetylcholine
receptor subunit alpha 10 protein.
Length = 450
Score = 48.0 bits (109), Expect = 4e-05
Identities = 44/166 (26%), Positives = 68/166 (40%), Gaps = 7/166 (4%)
Frame = +1
Query: 61 ILLPFLLTCAIASAAECENATSLSLMIDSLLATYDRDSPP--DSKIVVNLTLHLRHANI- 231
+LL FLL A E +L L D L A Y P D+ +N+TL + + I
Sbjct: 12 LLLLFLLPAECLGA---EGRLALKLFRD-LFANYTSALRPVADTDQTLNVTLEVTLSQII 67
Query: 232 --RESESTVRIQADLQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLLN-AXATTX 399
E + + ++ W D L W+ +G + S +WRPD+VL N A A
Sbjct: 68 DMDERNQVLTLYLWIRQEWTDAYLRWDPNAYGGLDAIRIPSSLVWRPDIVLYNKADAQPP 127
Query: 400 GDYALRARVSNNGSVSWIKRLDISXPISMQLDXWXNDMQTCTFKFG 537
G + + ++G+V W + + + D Q C FG
Sbjct: 128 GSASTNVVLRHDGAVRWDAPAITRSSCRVDVAAFPFDAQHCGLTFG 173
>AF199235-1|AAG00795.2| 450|Homo sapiens nicotinic acetylcholine
receptor subunit alpha 10 protein.
Length = 450
Score = 48.0 bits (109), Expect = 4e-05
Identities = 44/166 (26%), Positives = 68/166 (40%), Gaps = 7/166 (4%)
Frame = +1
Query: 61 ILLPFLLTCAIASAAECENATSLSLMIDSLLATYDRDSPP--DSKIVVNLTLHLRHANI- 231
+LL FLL A E +L L D L A Y P D+ +N+TL + + I
Sbjct: 12 LLLLFLLPAECLGA---EGRLALKLFRD-LFANYTSALRPVADTDQTLNVTLEVTLSQII 67
Query: 232 --RESESTVRIQADLQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLLN-AXATTX 399
E + + ++ W D L W+ +G + S +WRPD+VL N A A
Sbjct: 68 DMDERNQVLTLYLWIRQEWTDAYLRWDPNAYGGLDAIRIPSSLVWRPDIVLYNKADAQPP 127
Query: 400 GDYALRARVSNNGSVSWIKRLDISXPISMQLDXWXNDMQTCTFKFG 537
G + + ++G+V W + + + D Q C FG
Sbjct: 128 GSASTNVVLRHDGAVRWDAPAITRSSCRVDVAAFPFDAQHCGLTFG 173
>Z23141-1|CAA80672.1| 479|Homo sapiens cholinergic receptor,
nicotinic, alpha polypeptide 7 protein.
Length = 479
Score = 47.2 bits (107), Expect = 8e-05
Identities = 32/125 (25%), Positives = 57/125 (45%), Gaps = 2/125 (1%)
Frame = +1
Query: 169 DSPPDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSS 345
DS P + + +L+L L+ ++ E + LQM+W D L WN E+ G T
Sbjct: 24 DSQPLT-VYFSLSL-LQIMDVDEKNQVLTTNIWLQMSWTDHYLQWNVSEYPGVKTVRFPD 81
Query: 346 ERLWRPDVVLLN-AXATTXGDYALRARVSNNGSVSWIKRLDISXPISMQLDXWXNDMQTC 522
++W+PD++L N A + V+++G ++ + + + D+Q C
Sbjct: 82 GQIWKPDILLYNSADERFDATFHTNVLVNSSGHCQYLPPGIFKSSCYIDVRWFPFDVQHC 141
Query: 523 TFKFG 537
KFG
Sbjct: 142 KLKFG 146
>Y08420-1|CAA69697.1| 502|Homo sapiens nicotinic acetylcholine
receptor alpha7 subunit precursor protein.
Length = 502
Score = 47.2 bits (107), Expect = 8e-05
Identities = 32/125 (25%), Positives = 57/125 (45%), Gaps = 2/125 (1%)
Frame = +1
Query: 169 DSPPDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSS 345
DS P + + +L+L L+ ++ E + LQM+W D L WN E+ G T
Sbjct: 47 DSQPLT-VYFSLSL-LQIMDVDEKNQVLTTNIWLQMSWTDHYLQWNVSEYPGVKTVRFPD 104
Query: 346 ERLWRPDVVLLN-AXATTXGDYALRARVSNNGSVSWIKRLDISXPISMQLDXWXNDMQTC 522
++W+PD++L N A + V+++G ++ + + + D+Q C
Sbjct: 105 GQIWKPDILLYNSADERFDATFHTNVLVNSSGHCQYLPPGIFKSSCYIDVRWFPFDVQHC 164
Query: 523 TFKFG 537
KFG
Sbjct: 165 KLKFG 169
>X70297-1|CAA49778.1| 502|Homo sapiens neuronal nicotinic
acetylocholine receptor alpha-7 subunit protein.
Length = 502
Score = 47.2 bits (107), Expect = 8e-05
Identities = 32/125 (25%), Positives = 57/125 (45%), Gaps = 2/125 (1%)
Frame = +1
Query: 169 DSPPDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSS 345
DS P + + +L+L L+ ++ E + LQM+W D L WN E+ G T
Sbjct: 47 DSQPLT-VYFSLSL-LQIMDVDEKNQVLTTNIWLQMSWTDHYLQWNVSEYPGVKTVRFPD 104
Query: 346 ERLWRPDVVLLN-AXATTXGDYALRARVSNNGSVSWIKRLDISXPISMQLDXWXNDMQTC 522
++W+PD++L N A + V+++G ++ + + + D+Q C
Sbjct: 105 GQIWKPDILLYNSADERFDATFHTNVLVNSSGHCQYLPPGIFKSSCYIDVRWFPFDVQHC 164
Query: 523 TFKFG 537
KFG
Sbjct: 165 KLKFG 169
>U62436-1|AAB40114.1| 502|Homo sapiens nicotinic acetylcholine
receptor alpha7 subunit precursor protein.
Length = 502
Score = 47.2 bits (107), Expect = 8e-05
Identities = 32/125 (25%), Positives = 57/125 (45%), Gaps = 2/125 (1%)
Frame = +1
Query: 169 DSPPDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSS 345
DS P + + +L+L L+ ++ E + LQM+W D L WN E+ G T
Sbjct: 47 DSQPLT-VYFSLSL-LQIMDVDEKNQVLTTNIWLQMSWTDHYLQWNVSEYPGVKTVRFPD 104
Query: 346 ERLWRPDVVLLN-AXATTXGDYALRARVSNNGSVSWIKRLDISXPISMQLDXWXNDMQTC 522
++W+PD++L N A + V+++G ++ + + + D+Q C
Sbjct: 105 GQIWKPDILLYNSADERFDATFHTNVLVNSSGHCQYLPPGIFKSSCYIDVRWFPFDVQHC 164
Query: 523 TFKFG 537
KFG
Sbjct: 165 KLKFG 169
>DQ644022-1|ABG35128.1| 456|Homo sapiens 5-HT3 receptor subunit E
splice variant HTR3Ea protein.
Length = 456
Score = 47.2 bits (107), Expect = 8e-05
Identities = 24/90 (26%), Positives = 43/90 (47%), Gaps = 1/90 (1%)
Frame = +1
Query: 268 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAXATTXGDYALRARVSNNGSV 444
L+M W + +SWN E G + ++++ LW PD+ ++ L A VSN G +
Sbjct: 91 LEMVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEGRI 150
Query: 445 SWIKRLDISXPISMQLDXWXNDMQTCTFKF 534
+ K + + ++ + + D Q CT F
Sbjct: 151 RYKKPMKVDSICNLDIFYFPFDQQNCTLTF 180
>BC101185-1|AAI01186.1| 374|Homo sapiens HTR3E protein protein.
Length = 374
Score = 47.2 bits (107), Expect = 8e-05
Identities = 24/90 (26%), Positives = 43/90 (47%), Gaps = 1/90 (1%)
Frame = +1
Query: 268 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAXATTXGDYALRARVSNNGSV 444
L+M W + +SWN E G + ++++ LW PD+ ++ L A VSN G +
Sbjct: 20 LEMVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEGRI 79
Query: 445 SWIKRLDISXPISMQLDXWXNDMQTCTFKF 534
+ K + + ++ + + D Q CT F
Sbjct: 80 RYKKPMKVDSICNLDIFYFPFDQQNCTLTF 109
>BC101183-1|AAI01184.1| 471|Homo sapiens 5-hydroxytryptamine
(serotonin) receptor 3, family member E protein.
Length = 471
Score = 47.2 bits (107), Expect = 8e-05
Identities = 24/90 (26%), Positives = 43/90 (47%), Gaps = 1/90 (1%)
Frame = +1
Query: 268 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAXATTXGDYALRARVSNNGSV 444
L+M W + +SWN E G + ++++ LW PD+ ++ L A VSN G +
Sbjct: 106 LEMVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEGRI 165
Query: 445 SWIKRLDISXPISMQLDXWXNDMQTCTFKF 534
+ K + + ++ + + D Q CT F
Sbjct: 166 RYKKPMKVDSICNLDIFYFPFDQQNCTLTF 195
>BC101182-1|AAI01183.1| 471|Homo sapiens 5-hydroxytryptamine
(serotonin) receptor 3, family member E protein.
Length = 471
Score = 47.2 bits (107), Expect = 8e-05
Identities = 24/90 (26%), Positives = 43/90 (47%), Gaps = 1/90 (1%)
Frame = +1
Query: 268 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAXATTXGDYALRARVSNNGSV 444
L+M W + +SWN E G + ++++ LW PD+ ++ L A VSN G +
Sbjct: 106 LEMVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEGRI 165
Query: 445 SWIKRLDISXPISMQLDXWXNDMQTCTFKF 534
+ K + + ++ + + D Q CT F
Sbjct: 166 RYKKPMKVDSICNLDIFYFPFDQQNCTLTF 195
>AY159813-1|AAO38167.2| 471|Homo sapiens 5-hydroxytryptamine
serotonin receptor 3E protein.
Length = 471
Score = 47.2 bits (107), Expect = 8e-05
Identities = 24/90 (26%), Positives = 43/90 (47%), Gaps = 1/90 (1%)
Frame = +1
Query: 268 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAXATTXGDYALRARVSNNGSV 444
L+M W + +SWN E G + ++++ LW PD+ ++ L A VSN G +
Sbjct: 106 LEMVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEGRI 165
Query: 445 SWIKRLDISXPISMQLDXWXNDMQTCTFKF 534
+ K + + ++ + + D Q CT F
Sbjct: 166 RYKKPMKVDSICNLDIFYFPFDQQNCTLTF 195
>AJ586911-1|CAE52911.1| 502|Homo sapiens nicotinic acetylcholine
alpha-7 subunit protein.
Length = 502
Score = 47.2 bits (107), Expect = 8e-05
Identities = 32/125 (25%), Positives = 57/125 (45%), Gaps = 2/125 (1%)
Frame = +1
Query: 169 DSPPDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSS 345
DS P + + +L+L L+ ++ E + LQM+W D L WN E+ G T
Sbjct: 47 DSQPLT-VYFSLSL-LQIMDVDEKNQVLTTNIWLQMSWTDHYLQWNVSEYPGVKTVRFPD 104
Query: 346 ERLWRPDVVLLN-AXATTXGDYALRARVSNNGSVSWIKRLDISXPISMQLDXWXNDMQTC 522
++W+PD++L N A + V+++G ++ + + + D+Q C
Sbjct: 105 GQIWKPDILLYNSADERFDATFHTNVLVNSSGHCQYLPPGIFKSSCYIDVRWFPFDVQHC 164
Query: 523 TFKFG 537
KFG
Sbjct: 165 KLKFG 169
>BC096083-1|AAH96083.1| 198|Homo sapiens CHRNB4 protein protein.
Length = 198
Score = 46.8 bits (106), Expect = 1e-04
Identities = 33/119 (27%), Positives = 57/119 (47%), Gaps = 8/119 (6%)
Frame = +1
Query: 64 LLPFLLTCAIASAAECENATSLSLMIDSLL--ATYD---RDSPPDSKIV-VNLTLHLRHA 225
L+ F L A+ C A + ++D LL Y+ R + S+++ + L L L
Sbjct: 7 LVLFFLV-ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQL 65
Query: 226 -NIRESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAXATT 396
++ E E + L+ W D RL+WN+ + G + + ++R+W PD+VL N T
Sbjct: 66 ISVNEREQIMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNKSLRT 124
>BC096081-1|AAH96081.1| 198|Homo sapiens CHRNB4 protein protein.
Length = 198
Score = 46.8 bits (106), Expect = 1e-04
Identities = 33/119 (27%), Positives = 57/119 (47%), Gaps = 8/119 (6%)
Frame = +1
Query: 64 LLPFLLTCAIASAAECENATSLSLMIDSLL--ATYD---RDSPPDSKIV-VNLTLHLRHA 225
L+ F L A+ C A + ++D LL Y+ R + S+++ + L L L
Sbjct: 7 LVLFFLV-ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQL 65
Query: 226 -NIRESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAXATT 396
++ E E + L+ W D RL+WN+ + G + + ++R+W PD+VL N T
Sbjct: 66 ISVNEREQIMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNKSLRT 124
>U40583-1|AAA83561.1| 502|Homo sapiens alpha 7 neuronal nicotinic
acetylcholine receptor protein.
Length = 502
Score = 45.6 bits (103), Expect = 2e-04
Identities = 32/125 (25%), Positives = 55/125 (44%), Gaps = 2/125 (1%)
Frame = +1
Query: 169 DSPPDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSS 345
DS P + + +L L L+ ++ E + LQM+W D L WN E+ G T
Sbjct: 47 DSQPLT-VYFSLNL-LQIMDVDEKNQVLTTNIWLQMSWTDHYLQWNVSEYPGVKTVRFPD 104
Query: 346 ERLWRPDVVLLN-AXATTXGDYALRARVSNNGSVSWIKRLDISXPISMQLDXWXNDMQTC 522
++W+PD++L N A + V+ +G ++ + + + D+Q C
Sbjct: 105 GQIWKPDILLYNSADERFDATFHTNVLVNPSGHCQYLPPGIFKSSCYIDVRWFPFDVQHC 164
Query: 523 TFKFG 537
KFG
Sbjct: 165 KLKFG 169
>BC131799-1|AAI31800.1| 447|Homo sapiens 5-hydroxytryptamine
(serotonin) receptor 3, family member C protein.
Length = 447
Score = 45.6 bits (103), Expect = 2e-04
Identities = 22/90 (24%), Positives = 44/90 (48%), Gaps = 1/90 (1%)
Frame = +1
Query: 268 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAXATTXGDYALRARVSNNGSV 444
+ + W + ++WN E G + V +E LW PD+ ++ + L A +S+ G +
Sbjct: 91 MDLVWDNPFINWNPKECVGINKLTVLAENLWLPDIFIVESMDVDQTPSGLTAYISSEGRI 150
Query: 445 SWIKRLDISXPISMQLDXWXNDMQTCTFKF 534
+ K + ++ ++ + + D Q CTF F
Sbjct: 151 KYDKPMRVTSICNLDIFYFPFDQQNCTFTF 180
>AY349353-1|AAQ93477.1| 456|Homo sapiens 5-HT3c1 serotonin
receptor-like protein protein.
Length = 456
Score = 45.6 bits (103), Expect = 2e-04
Identities = 24/94 (25%), Positives = 44/94 (46%), Gaps = 1/94 (1%)
Frame = +1
Query: 256 IQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAXATTXGDYALRARVSN 432
+ A L + W + +SWN E G + ++++ LW PD+ ++ L A VSN
Sbjct: 87 MSAILDVVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSN 146
Query: 433 NGSVSWIKRLDISXPISMQLDXWXNDMQTCTFKF 534
G + + K + + ++ + + D Q CT F
Sbjct: 147 EGRIRYKKPMKVDSICNLDIFYFPFDQQNCTLTF 180
>AY349352-1|AAQ93476.1| 441|Homo sapiens 5-HT3c1 serotonin
receptor-like protein protein.
Length = 441
Score = 45.6 bits (103), Expect = 2e-04
Identities = 24/94 (25%), Positives = 44/94 (46%), Gaps = 1/94 (1%)
Frame = +1
Query: 256 IQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAXATTXGDYALRARVSN 432
+ A L + W + +SWN E G + ++++ LW PD+ ++ L A VSN
Sbjct: 72 MSAILDVVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSN 131
Query: 433 NGSVSWIKRLDISXPISMQLDXWXNDMQTCTFKF 534
G + + K + + ++ + + D Q CT F
Sbjct: 132 EGRIRYKKPMKVDSICNLDIFYFPFDQQNCTLTF 165
>AF385585-1|AAK68111.1| 502|Homo sapiens nicotinic cholinergic
receptor alpha 7 protein.
Length = 502
Score = 45.6 bits (103), Expect = 2e-04
Identities = 32/125 (25%), Positives = 55/125 (44%), Gaps = 2/125 (1%)
Frame = +1
Query: 169 DSPPDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSS 345
DS P + + +L L L+ ++ E + LQM+W D L WN E+ G T
Sbjct: 47 DSQPLT-VYFSLNL-LQIMDVDEKNQVLTTNIWLQMSWTDHYLQWNVSEYPGVKTVRFPD 104
Query: 346 ERLWRPDVVLLN-AXATTXGDYALRARVSNNGSVSWIKRLDISXPISMQLDXWXNDMQTC 522
++W+PD++L N A + V+ +G ++ + + + D+Q C
Sbjct: 105 GQIWKPDILLYNSADERFDATFHTNVLVNPSGHCQYLPPGIFKSSCYIDVRWFPFDVQHC 164
Query: 523 TFKFG 537
KFG
Sbjct: 165 KLKFG 169
>BC110597-1|AAI10598.1| 411|Homo sapiens ligand-gated ion channel,
zinc activated 1 protein.
Length = 411
Score = 45.2 bits (102), Expect = 3e-04
Identities = 24/89 (26%), Positives = 39/89 (43%)
Frame = +1
Query: 268 LQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAXATTXGDYALRARVSNNGSVS 447
L+++W+D RL+WN + E LW P + +L A D + +ARV +G V
Sbjct: 86 LRLSWLDTRLAWNTSAHPRHAITLPWESLWTPRLTILEALWVDWRDQSPQARVDQDGHVK 145
Query: 448 WIKRLDISXPISMQLDXWXNDMQTCTFKF 534
L + +L + D C+ F
Sbjct: 146 LNLALTTETNCNFELLHFPRDHSNCSLSF 174
>AK122638-1|BAC85499.1| 266|Homo sapiens yte protein of 76kDa)
(LCP2). protein.
Length = 266
Score = 45.2 bits (102), Expect = 3e-04
Identities = 24/89 (26%), Positives = 39/89 (43%)
Frame = +1
Query: 268 LQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAXATTXGDYALRARVSNNGSVS 447
L+++W+D RL+WN + E LW P + +L A D + +ARV +G V
Sbjct: 87 LRLSWLDTRLAWNTSAHPRHAITLPWESLWTPRLTILEALWVDWRDQSPQARVDQDGHVK 146
Query: 448 WIKRLDISXPISMQLDXWXNDMQTCTFKF 534
L + +L + D C+ F
Sbjct: 147 LNLALTTETNCNFELLHFPRDHSNCSLSF 175
>AF512521-1|AAO20969.1| 411|Homo sapiens ligand-gated ion channel
subunit protein.
Length = 411
Score = 45.2 bits (102), Expect = 3e-04
Identities = 24/89 (26%), Positives = 39/89 (43%)
Frame = +1
Query: 268 LQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAXATTXGDYALRARVSNNGSVS 447
L+++W+D RL+WN + E LW P + +L A D + +ARV +G V
Sbjct: 86 LRLSWLDTRLAWNTSAHPRHAITLPWESLWTPRLTILEALWVDWRDQSPQARVDQDGHVK 145
Query: 448 WIKRLDISXPISMQLDXWXNDMQTCTFKF 534
L + +L + D C+ F
Sbjct: 146 LNLALTTETNCNFELLHFPRDHSNCSLSF 174
>AF459285-1|AAL66182.1| 447|Homo sapiens 5-hydroxytryptamine
receptor 3 subunit C protein.
Length = 447
Score = 45.2 bits (102), Expect = 3e-04
Identities = 22/90 (24%), Positives = 43/90 (47%), Gaps = 1/90 (1%)
Frame = +1
Query: 268 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAXATTXGDYALRARVSNNGSV 444
+ + W + ++WN E G + V +E LW PD+ ++ + L A +S+ G +
Sbjct: 91 MDLVWDNPFINWNPKECVGINKLTVLAENLWLPDIFIVESMDVDQTPSGLTAYISSEGRI 150
Query: 445 SWIKRLDISXPISMQLDXWXNDMQTCTFKF 534
+ K + ++ + + + D Q CTF F
Sbjct: 151 KYDKPMRVTSICKLDIFYFPFDQQNCTFTF 180
>AB223030-1|BAE19924.1| 411|Homo sapiens ligand-gated ion-channel
receptor L2 protein.
Length = 411
Score = 44.8 bits (101), Expect = 4e-04
Identities = 24/89 (26%), Positives = 39/89 (43%)
Frame = +1
Query: 268 LQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAXATTXGDYALRARVSNNGSVS 447
L+++W+D RL+WN + E LW P + +L A D + +ARV +G V
Sbjct: 86 LRLSWLDTRLAWNTSAHPRHAITLPWESLWTPRLTILEALWVDWRDQSPQARVDQDGHVK 145
Query: 448 WIKRLDISXPISMQLDXWXNDMQTCTFKF 534
L + +L + D C+ F
Sbjct: 146 LNLALATETNCNFELLHFPRDHSNCSLSF 174
>L08485-1|AAA58490.1| 462|Homo sapiens GABA-benzodiazepine receptor
alpha-5-subunit protein.
Length = 462
Score = 43.6 bits (98), Expect = 0.001
Identities = 34/149 (22%), Positives = 63/149 (42%), Gaps = 7/149 (4%)
Frame = +1
Query: 112 ENATSLSLMIDSLLATYDRDSPPD--SKIV-VNLTLHLRHAN-IRESESTVRIQADLQMN 279
+N T + ++D LL YD P +I V +++ + ++E I + +
Sbjct: 44 DNITIFTRILDGLLDGYDNRLRPGLGERITQVRTDIYVTSFGPVSDTEMEYTIDVFFRQS 103
Query: 280 WIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAXATTXGDYALR---ARVSNNGSVSW 450
W D+RL + + + ++W PD N + + R+ ++G++ +
Sbjct: 104 WKDERLRFKGPMQRLPLNNLLASKIWTPDTFFHNGKKSIAHNMTTPNKLLRLEDDGTLLY 163
Query: 451 IKRLDISXPISMQLDXWXNDMQTCTFKFG 537
RL IS MQL+ + D C KFG
Sbjct: 164 TMRLTISAECPMQLEDFPMDAHACPLKFG 192
>BT009830-1|AAP88832.1| 462|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 5 protein.
Length = 462
Score = 43.6 bits (98), Expect = 0.001
Identities = 34/149 (22%), Positives = 63/149 (42%), Gaps = 7/149 (4%)
Frame = +1
Query: 112 ENATSLSLMIDSLLATYDRDSPPD--SKIV-VNLTLHLRHAN-IRESESTVRIQADLQMN 279
+N T + ++D LL YD P +I V +++ + ++E I + +
Sbjct: 44 DNITIFTRILDGLLDGYDNRLRPGLGERITQVRTDIYVTSFGPVSDTEMEYTIDVFFRQS 103
Query: 280 WIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAXATTXGDYALR---ARVSNNGSVSW 450
W D+RL + + + ++W PD N + + R+ ++G++ +
Sbjct: 104 WKDERLRFKGPMQRLPLNNLLASKIWTPDTFFHNGKKSIAHNMTTPNKLLRLEDDGTLLY 163
Query: 451 IKRLDISXPISMQLDXWXNDMQTCTFKFG 537
RL IS MQL+ + D C KFG
Sbjct: 164 TMRLTISAECPMQLEDFPMDAHACPLKFG 192
>BC113575-1|AAI13576.1| 479|Homo sapiens cholinergic receptor,
nicotinic, alpha 9 protein.
Length = 479
Score = 43.6 bits (98), Expect = 0.001
Identities = 34/153 (22%), Positives = 65/153 (42%), Gaps = 7/153 (4%)
Frame = +1
Query: 100 AAECENATSLSLMIDSLLATYDRDSPP--DSKIVVNLTLHLRHANIRESESTVRIQAD-- 267
AAE + + + L Y P D+ V+N+TL + + I++ + +I
Sbjct: 22 AAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQITLSQIKDMDERNQILTAYL 81
Query: 268 -LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLN-AXATTXGDYALRARVSNNG 438
++ W D L+W+ ++ G + + S+ +WRPD+VL N A + + +G
Sbjct: 82 WIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKADDESSEPVNTNVVLRYDG 141
Query: 439 SVSWIKRLDISXPISMQLDXWXNDMQTCTFKFG 537
++W + + + D Q C FG
Sbjct: 142 LITWDAPAITKSSCVVDVTYFPFDNQQCNLTFG 174
>BC113549-1|AAI13550.1| 479|Homo sapiens cholinergic receptor,
nicotinic, alpha 9 protein.
Length = 479
Score = 43.6 bits (98), Expect = 0.001
Identities = 34/153 (22%), Positives = 65/153 (42%), Gaps = 7/153 (4%)
Frame = +1
Query: 100 AAECENATSLSLMIDSLLATYDRDSPP--DSKIVVNLTLHLRHANIRESESTVRIQAD-- 267
AAE + + + L Y P D+ V+N+TL + + I++ + +I
Sbjct: 22 AAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQITLSQIKDMDERNQILTAYL 81
Query: 268 -LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLN-AXATTXGDYALRARVSNNG 438
++ W D L+W+ ++ G + + S+ +WRPD+VL N A + + +G
Sbjct: 82 WIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKADDESSEPVNTNVVLRYDG 141
Query: 439 SVSWIKRLDISXPISMQLDXWXNDMQTCTFKFG 537
++W + + + D Q C FG
Sbjct: 142 LITWDAPAITKSSCVVDVTYFPFDNQQCNLTFG 174
>BC113422-1|AAI13423.1| 462|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 5 protein.
Length = 462
Score = 43.6 bits (98), Expect = 0.001
Identities = 34/149 (22%), Positives = 63/149 (42%), Gaps = 7/149 (4%)
Frame = +1
Query: 112 ENATSLSLMIDSLLATYDRDSPPD--SKIV-VNLTLHLRHAN-IRESESTVRIQADLQMN 279
+N T + ++D LL YD P +I V +++ + ++E I + +
Sbjct: 44 DNITIFTRILDGLLDGYDNRLRPGLGERITQVRTDIYVTSFGPVSDTEMEYTIDVFFRQS 103
Query: 280 WIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAXATTXGDYALR---ARVSNNGSVSW 450
W D+RL + + + ++W PD N + + R+ ++G++ +
Sbjct: 104 WKDERLRFKGPMQRLPLNNLLASKIWTPDTFFHNGKKSIAHNMTTPNKLLRLEDDGTLLY 163
Query: 451 IKRLDISXPISMQLDXWXNDMQTCTFKFG 537
RL IS MQL+ + D C KFG
Sbjct: 164 TMRLTISAECPMQLEDFPMDAHACPLKFG 192
>BC111979-1|AAI11980.1| 462|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 5, precursor protein.
Length = 462
Score = 43.6 bits (98), Expect = 0.001
Identities = 34/149 (22%), Positives = 63/149 (42%), Gaps = 7/149 (4%)
Frame = +1
Query: 112 ENATSLSLMIDSLLATYDRDSPPD--SKIV-VNLTLHLRHAN-IRESESTVRIQADLQMN 279
+N T + ++D LL YD P +I V +++ + ++E I + +
Sbjct: 44 DNITIFTRILDGLLDGYDNRLRPGLGERITQVRTDIYVTSFGPVSDTEMEYTIDVFFRQS 103
Query: 280 WIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAXATTXGDYALR---ARVSNNGSVSW 450
W D+RL + + + ++W PD N + + R+ ++G++ +
Sbjct: 104 WKDERLRFKGPMQRLPLNNLLASKIWTPDTFFHNGKKSIAHNMTTPNKLLRLEDDGTLLY 163
Query: 451 IKRLDISXPISMQLDXWXNDMQTCTFKFG 537
RL IS MQL+ + D C KFG
Sbjct: 164 TMRLTISAECPMQLEDFPMDAHACPLKFG 192
>AY123244-1|AAM74523.1| 479|Homo sapiens nicotinic acetylcholine
receptor subunit alpha 9 protein.
Length = 479
Score = 43.6 bits (98), Expect = 0.001
Identities = 34/153 (22%), Positives = 65/153 (42%), Gaps = 7/153 (4%)
Frame = +1
Query: 100 AAECENATSLSLMIDSLLATYDRDSPP--DSKIVVNLTLHLRHANIRESESTVRIQAD-- 267
AAE + + + L Y P D+ V+N+TL + + I++ + +I
Sbjct: 22 AAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQITLSQIKDMDERNQILTAYL 81
Query: 268 -LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLN-AXATTXGDYALRARVSNNG 438
++ W D L+W+ ++ G + + S+ +WRPD+VL N A + + +G
Sbjct: 82 WIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKADDESSEPVNTNVVLRYDG 141
Query: 439 SVSWIKRLDISXPISMQLDXWXNDMQTCTFKFG 537
++W + + + D Q C FG
Sbjct: 142 LITWDAPAITKSSCVVDVTYFPFDNQQCNLTFG 174
>AJ243342-1|CAB65091.1| 479|Homo sapiens nicotinic acetylcholine
receptor alpha 9 subunit protein.
Length = 479
Score = 43.6 bits (98), Expect = 0.001
Identities = 34/153 (22%), Positives = 65/153 (42%), Gaps = 7/153 (4%)
Frame = +1
Query: 100 AAECENATSLSLMIDSLLATYDRDSPP--DSKIVVNLTLHLRHANIRESESTVRIQAD-- 267
AAE + + + L Y P D+ V+N+TL + + I++ + +I
Sbjct: 22 AAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQITLSQIKDMDERNQILTAYL 81
Query: 268 -LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLN-AXATTXGDYALRARVSNNG 438
++ W D L+W+ ++ G + + S+ +WRPD+VL N A + + +G
Sbjct: 82 WIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKADDESSEPVNTNVVLRYDG 141
Query: 439 SVSWIKRLDISXPISMQLDXWXNDMQTCTFKFG 537
++W + + + D Q C FG
Sbjct: 142 LITWDAPAITKSSCVVDVTYFPFDNQQCNLTFG 174
>AF227732-1|AAF61920.1| 470|Homo sapiens nicotinic acetylcholine
receptor alpha 9 subunit protein.
Length = 470
Score = 43.6 bits (98), Expect = 0.001
Identities = 34/153 (22%), Positives = 65/153 (42%), Gaps = 7/153 (4%)
Frame = +1
Query: 100 AAECENATSLSLMIDSLLATYDRDSPP--DSKIVVNLTLHLRHANIRESESTVRIQAD-- 267
AAE + + + L Y P D+ V+N+TL + + I++ + +I
Sbjct: 16 AAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQITLSQIKDMDERNQILTAYL 75
Query: 268 -LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLN-AXATTXGDYALRARVSNNG 438
++ W D L+W+ ++ G + + S+ +WRPD+VL N A + + +G
Sbjct: 76 WIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKADDESSEPVNTNVVLRYDG 135
Query: 439 SVSWIKRLDISXPISMQLDXWXNDMQTCTFKFG 537
++W + + + D Q C FG
Sbjct: 136 LITWDAPAITKSSCVVDVTYFPFDNQQCNLTFG 168
>AC118275-1|AAY40986.1| 479|Homo sapiens unknown protein.
Length = 479
Score = 43.6 bits (98), Expect = 0.001
Identities = 34/153 (22%), Positives = 65/153 (42%), Gaps = 7/153 (4%)
Frame = +1
Query: 100 AAECENATSLSLMIDSLLATYDRDSPP--DSKIVVNLTLHLRHANIRESESTVRIQAD-- 267
AAE + + + L Y P D+ V+N+TL + + I++ + +I
Sbjct: 22 AAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQITLSQIKDMDERNQILTAYL 81
Query: 268 -LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLN-AXATTXGDYALRARVSNNG 438
++ W D L+W+ ++ G + + S+ +WRPD+VL N A + + +G
Sbjct: 82 WIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKADDESSEPVNTNVVLRYDG 141
Query: 439 SVSWIKRLDISXPISMQLDXWXNDMQTCTFKFG 537
++W + + + D Q C FG
Sbjct: 142 LITWDAPAITKSSCVVDVTYFPFDNQQCNLTFG 174
>U77731-2|AAB38273.1| 360|Homo sapiens glycine receptor alpha 2B
subunit protein.
Length = 360
Score = 42.7 bits (96), Expect = 0.002
Identities = 30/122 (24%), Positives = 52/122 (42%), Gaps = 4/122 (3%)
Frame = +1
Query: 178 PDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERL 354
P + N+ ++ +I E+ R+ L+ W D RL+++ S + +
Sbjct: 69 PPVNVTCNIFIN-SFGSIAETTMDYRVNIFLRQQWNDSRLAYSEYPDDSLDLDPSMLDSI 127
Query: 355 WRPDVVLLNAXATTXGDYALR---ARVSNNGSVSWIKRLDISXPISMQLDXWXNDMQTCT 525
W+PD+ N D R+S NG V + RL ++ M L + D+QTCT
Sbjct: 128 WKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNFPMDVQTCT 187
Query: 526 FK 531
+
Sbjct: 188 MQ 189
>S77554-1|AAB33983.1| 474|Homo sapiens GABAA receptor beta 2
subunit protein.
Length = 474
Score = 42.7 bits (96), Expect = 0.002
Identities = 40/169 (23%), Positives = 70/169 (41%), Gaps = 10/169 (5%)
Frame = +1
Query: 55 YIILLPFLLTCAIASAAECENATSLSLM---IDSLLATYDRDSPPD---SKIVVNLTLHL 216
Y + F L A A + +++SL+ +D LL YD PD + V + + +
Sbjct: 9 YFGIWSFPLIIAAVCAQSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDI 68
Query: 217 RHAN-IRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAXAT 393
+ + E + Q W DKRLS+N + +++LW PD LN +
Sbjct: 69 ASIDMVSEVNMDYTLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLNDKKS 128
Query: 394 TXGDYALR---ARVSNNGSVSWIKRLDISXPISMQLDXWXNDMQTCTFK 531
++ R+ +G+V + R+ + M L + D Q CT +
Sbjct: 129 FVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLE 177
>S77553-1|AAB33982.1| 512|Homo sapiens GABAA receptor beta 2
subunit protein.
Length = 512
Score = 42.7 bits (96), Expect = 0.002
Identities = 40/169 (23%), Positives = 70/169 (41%), Gaps = 10/169 (5%)
Frame = +1
Query: 55 YIILLPFLLTCAIASAAECENATSLSLM---IDSLLATYDRDSPPD---SKIVVNLTLHL 216
Y + F L A A + +++SL+ +D LL YD PD + V + + +
Sbjct: 9 YFGIWSFPLIIAAVCAQSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDI 68
Query: 217 RHAN-IRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAXAT 393
+ + E + Q W DKRLS+N + +++LW PD LN +
Sbjct: 69 ASIDMVSEVNMDYTLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLNDKKS 128
Query: 394 TXGDYALR---ARVSNNGSVSWIKRLDISXPISMQLDXWXNDMQTCTFK 531
++ R+ +G+V + R+ + M L + D Q CT +
Sbjct: 129 FVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLE 177
>S67368-1|AAB29370.1| 474|Homo sapiens gamma-aminobutyric acid A
receptor beta 2 subunit protein.
Length = 474
Score = 42.7 bits (96), Expect = 0.002
Identities = 40/169 (23%), Positives = 70/169 (41%), Gaps = 10/169 (5%)
Frame = +1
Query: 55 YIILLPFLLTCAIASAAECENATSLSLM---IDSLLATYDRDSPPD---SKIVVNLTLHL 216
Y + F L A A + +++SL+ +D LL YD PD + V + + +
Sbjct: 9 YFGIWSFPLIIAAVCAQSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDI 68
Query: 217 RHAN-IRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAXAT 393
+ + E + Q W DKRLS+N + +++LW PD LN +
Sbjct: 69 ASIDMVSEVNMDYTLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLNDKKS 128
Query: 394 TXGDYALR---ARVSNNGSVSWIKRLDISXPISMQLDXWXNDMQTCTFK 531
++ R+ +G+V + R+ + M L + D Q CT +
Sbjct: 129 FVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLE 177
>CR450343-1|CAG29339.1| 452|Homo sapiens GLRA2 protein.
Length = 452
Score = 42.7 bits (96), Expect = 0.002
Identities = 30/122 (24%), Positives = 52/122 (42%), Gaps = 4/122 (3%)
Frame = +1
Query: 178 PDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERL 354
P + N+ ++ +I E+ R+ L+ W D RL+++ S + +
Sbjct: 69 PPVNVTCNIFIN-SFGSIAETTMDYRVNIFLRQQWNDSRLAYSEYPDDSLDLDPSMLDSI 127
Query: 355 WRPDVVLLNAXATTXGDYALR---ARVSNNGSVSWIKRLDISXPISMQLDXWXNDMQTCT 525
W+PD+ N D R+S NG V + RL ++ M L + D+QTCT
Sbjct: 128 WKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNFPMDVQTCT 187
Query: 526 FK 531
+
Sbjct: 188 MQ 189
>BC105639-1|AAI05640.1| 474|Homo sapiens GABRB2 protein protein.
Length = 474
Score = 42.7 bits (96), Expect = 0.002
Identities = 40/169 (23%), Positives = 70/169 (41%), Gaps = 10/169 (5%)
Frame = +1
Query: 55 YIILLPFLLTCAIASAAECENATSLSLM---IDSLLATYDRDSPPD---SKIVVNLTLHL 216
Y + F L A A + +++SL+ +D LL YD PD + V + + +
Sbjct: 9 YFGIWSFPLIIAAVCAQSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDI 68
Query: 217 RHAN-IRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAXAT 393
+ + E + Q W DKRLS+N + +++LW PD LN +
Sbjct: 69 ASIDMVSEVNMDYTLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLNDKKS 128
Query: 394 TXGDYALR---ARVSNNGSVSWIKRLDISXPISMQLDXWXNDMQTCTFK 531
++ R+ +G+V + R+ + M L + D Q CT +
Sbjct: 129 FVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLE 177
>BC099719-1|AAH99719.1| 474|Homo sapiens GABRB2 protein protein.
Length = 474
Score = 42.7 bits (96), Expect = 0.002
Identities = 40/169 (23%), Positives = 70/169 (41%), Gaps = 10/169 (5%)
Frame = +1
Query: 55 YIILLPFLLTCAIASAAECENATSLSLM---IDSLLATYDRDSPPD---SKIVVNLTLHL 216
Y + F L A A + +++SL+ +D LL YD PD + V + + +
Sbjct: 9 YFGIWSFPLIIAAVCAQSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDI 68
Query: 217 RHAN-IRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAXAT 393
+ + E + Q W DKRLS+N + +++LW PD LN +
Sbjct: 69 ASIDMVSEVNMDYTLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLNDKKS 128
Query: 394 TXGDYALR---ARVSNNGSVSWIKRLDISXPISMQLDXWXNDMQTCTFK 531
++ R+ +G+V + R+ + M L + D Q CT +
Sbjct: 129 FVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLE 177
>BC099705-1|AAH99705.1| 474|Homo sapiens GABRB2 protein protein.
Length = 474
Score = 42.7 bits (96), Expect = 0.002
Identities = 40/169 (23%), Positives = 70/169 (41%), Gaps = 10/169 (5%)
Frame = +1
Query: 55 YIILLPFLLTCAIASAAECENATSLSLM---IDSLLATYDRDSPPD---SKIVVNLTLHL 216
Y + F L A A + +++SL+ +D LL YD PD + V + + +
Sbjct: 9 YFGIWSFPLIIAAVCAQSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDI 68
Query: 217 RHAN-IRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAXAT 393
+ + E + Q W DKRLS+N + +++LW PD LN +
Sbjct: 69 ASIDMVSEVNMDYTLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLNDKKS 128
Query: 394 TXGDYALR---ARVSNNGSVSWIKRLDISXPISMQLDXWXNDMQTCTFK 531
++ R+ +G+V + R+ + M L + D Q CT +
Sbjct: 129 FVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLE 177
>AY437084-1|AAR87843.1| 452|Homo sapiens glycine receptor alpha2
subunit B protein.
Length = 452
Score = 42.7 bits (96), Expect = 0.002
Identities = 30/122 (24%), Positives = 52/122 (42%), Gaps = 4/122 (3%)
Frame = +1
Query: 178 PDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERL 354
P + N+ ++ +I E+ R+ L+ W D RL+++ S + +
Sbjct: 69 PPVNVTCNIFIN-SFGSIAETTMDYRVNIFLRQQWNDSRLAYSEYPDDSLDLDPSMLDSI 127
Query: 355 WRPDVVLLNAXATTXGDYALR---ARVSNNGSVSWIKRLDISXPISMQLDXWXNDMQTCT 525
W+PD+ N D R+S NG V + RL ++ M L + D+QTCT
Sbjct: 128 WKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNFPMDVQTCT 187
Query: 526 FK 531
+
Sbjct: 188 MQ 189
>X52008-1|CAA36257.1| 452|Homo sapiens inhibitory glycine receptor
protein.
Length = 452
Score = 42.3 bits (95), Expect = 0.002
Identities = 29/122 (23%), Positives = 52/122 (42%), Gaps = 4/122 (3%)
Frame = +1
Query: 178 PDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERL 354
P + N+ ++ ++ E+ R+ L+ W D RL+++ S + +
Sbjct: 69 PPVNVTCNIFIN-SFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPDDSLDLDPSMLDSI 127
Query: 355 WRPDVVLLNAXATTXGDYALR---ARVSNNGSVSWIKRLDISXPISMQLDXWXNDMQTCT 525
W+PD+ N D R+S NG V + RL ++ M L + D+QTCT
Sbjct: 128 WKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNFPMDVQTCT 187
Query: 526 FK 531
+
Sbjct: 188 MQ 189
>U77731-1|AAB38272.1| 360|Homo sapiens glycine receptor alpha 2
subunit protein.
Length = 360
Score = 42.3 bits (95), Expect = 0.002
Identities = 29/122 (23%), Positives = 52/122 (42%), Gaps = 4/122 (3%)
Frame = +1
Query: 178 PDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERL 354
P + N+ ++ ++ E+ R+ L+ W D RL+++ S + +
Sbjct: 69 PPVNVTCNIFIN-SFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPDDSLDLDPSMLDSI 127
Query: 355 WRPDVVLLNAXATTXGDYALR---ARVSNNGSVSWIKRLDISXPISMQLDXWXNDMQTCT 525
W+PD+ N D R+S NG V + RL ++ M L + D+QTCT
Sbjct: 128 WKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNFPMDVQTCT 187
Query: 526 FK 531
+
Sbjct: 188 MQ 189
>M59216-1|AAA35862.1| 474|Homo sapiens gamma-aminobutyric acid
receptor beta-1 subunit protein.
Length = 474
Score = 42.3 bits (95), Expect = 0.002
Identities = 38/167 (22%), Positives = 70/167 (41%), Gaps = 9/167 (5%)
Frame = +1
Query: 58 IILLPFLLT--CAIASAAECENATSLSLMIDSLLATYDRDSPPD---SKIVVNLTLHLRH 222
++ P ++T C S E N + + +D LL YD PD + V + + +
Sbjct: 12 LLSFPVMITMVCCAHSTNEPSNMSYVKETVDRLLKGYDIRLRPDFGGPPVDVGMRIDVAS 71
Query: 223 AN-IRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAXATTX 399
+ + E + Q +W DKRLS++ + +++LW PD LN +
Sbjct: 72 IDMVSEVNMDYTLTMYFQQSWKDKRLSYSGIPLNLTLDNRVADQLWVPDTYFLNDKKSFV 131
Query: 400 GDYALR---ARVSNNGSVSWIKRLDISXPISMQLDXWXNDMQTCTFK 531
++ R+ +G+V + R+ + M L + D Q CT +
Sbjct: 132 HGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLE 178
>BC032864-1|AAH32864.1| 452|Homo sapiens glycine receptor, alpha 2
protein.
Length = 452
Score = 42.3 bits (95), Expect = 0.002
Identities = 29/122 (23%), Positives = 52/122 (42%), Gaps = 4/122 (3%)
Frame = +1
Query: 178 PDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERL 354
P + N+ ++ ++ E+ R+ L+ W D RL+++ S + +
Sbjct: 69 PPVNVTCNIFIN-SFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPDDSLDLDPSMLDSI 127
Query: 355 WRPDVVLLNAXATTXGDYALR---ARVSNNGSVSWIKRLDISXPISMQLDXWXNDMQTCT 525
W+PD+ N D R+S NG V + RL ++ M L + D+QTCT
Sbjct: 128 WKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNFPMDVQTCT 187
Query: 526 FK 531
+
Sbjct: 188 MQ 189
>BC028629-1|AAH28629.1| 492|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 3 protein.
Length = 492
Score = 42.3 bits (95), Expect = 0.002
Identities = 32/149 (21%), Positives = 62/149 (41%), Gaps = 7/149 (4%)
Frame = +1
Query: 112 ENATSLSLMIDSLLATYDRDSPP---DSKIVVNLTLHLRHAN-IRESESTVRIQADLQMN 279
+N T + ++D LL YD P D+ V +++ + +++ I +
Sbjct: 62 DNITIFTRILDRLLDGYDNRLRPGLGDAVTEVKTDIYVTSFGPVSDTDMEYTIDVFFRQT 121
Query: 280 WIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAXATTXGDYALR---ARVSNNGSVSW 450
W D+RL ++ + + ++W PD N + + R+ +NG++ +
Sbjct: 122 WHDERLKFDGPMKILPLNNLLASKIWTPDTFFHNGKKSVAHNMTTPNKLLRLVDNGTLPY 181
Query: 451 IKRLDISXPISMQLDXWXNDMQTCTFKFG 537
RL I M L+ + D+ C KFG
Sbjct: 182 TMRLTIHAECPMHLEDFPMDVHACPLKFG 210
>AY437083-1|AAR87842.1| 452|Homo sapiens glycine receptor alpha2
subunit A protein.
Length = 452
Score = 42.3 bits (95), Expect = 0.002
Identities = 29/122 (23%), Positives = 52/122 (42%), Gaps = 4/122 (3%)
Frame = +1
Query: 178 PDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERL 354
P + N+ ++ ++ E+ R+ L+ W D RL+++ S + +
Sbjct: 69 PPVNVTCNIFIN-SFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPDDSLDLDPSMLDSI 127
Query: 355 WRPDVVLLNAXATTXGDYALR---ARVSNNGSVSWIKRLDISXPISMQLDXWXNDMQTCT 525
W+PD+ N D R+S NG V + RL ++ M L + D+QTCT
Sbjct: 128 WKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNFPMDVQTCT 187
Query: 526 FK 531
+
Sbjct: 188 MQ 189
>AF053495-1|AAC35290.1| 452|Homo sapiens glycine receptor alpha 2
subunit protein.
Length = 452
Score = 42.3 bits (95), Expect = 0.002
Identities = 29/122 (23%), Positives = 52/122 (42%), Gaps = 4/122 (3%)
Frame = +1
Query: 178 PDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERL 354
P + N+ ++ ++ E+ R+ L+ W D RL+++ S + +
Sbjct: 69 PPVNVTCNIFIN-SFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPDDSLDLDPSMLDSI 127
Query: 355 WRPDVVLLNAXATTXGDYALR---ARVSNNGSVSWIKRLDISXPISMQLDXWXNDMQTCT 525
W+PD+ N D R+S NG V + RL ++ M L + D+QTCT
Sbjct: 128 WKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNFPMDVQTCT 187
Query: 526 FK 531
+
Sbjct: 188 MQ 189
>S62908-1|AAB27279.1| 492|Homo sapiens gamma-aminobutyric acidA
receptor alpha 3 subunit protein.
Length = 492
Score = 41.9 bits (94), Expect = 0.003
Identities = 32/149 (21%), Positives = 62/149 (41%), Gaps = 7/149 (4%)
Frame = +1
Query: 112 ENATSLSLMIDSLLATYDRDSPP---DSKIVVNLTLHLRHAN-IRESESTVRIQADLQMN 279
+N T + ++D LL YD P D+ V +++ + +++ I +
Sbjct: 62 DNITIFTRILDRLLDGYDNRLRPGLGDAVTEVKTDIYVTSFGPVSDTDMEYTIDVFFRQT 121
Query: 280 WIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAXATTXGDYALR---ARVSNNGSVSW 450
W D+RL ++ + + ++W PD N + + R+ +NG++ +
Sbjct: 122 WHDERLKFDGPMKILPLNNLLASKIWTPDTFFHNGKKSVAHNMTTPNKLLRLVDNGTLLY 181
Query: 451 IKRLDISXPISMQLDXWXNDMQTCTFKFG 537
RL I M L+ + D+ C KFG
Sbjct: 182 TMRLTIHAECPMHLEDFPMDVHACPLKFG 210
>AF166361-1|AAG12455.1| 492|Homo sapiens GABA receptor subunit
alpha 3 protein.
Length = 492
Score = 41.9 bits (94), Expect = 0.003
Identities = 32/149 (21%), Positives = 62/149 (41%), Gaps = 7/149 (4%)
Frame = +1
Query: 112 ENATSLSLMIDSLLATYDRDSPP---DSKIVVNLTLHLRHAN-IRESESTVRIQADLQMN 279
+N T + ++D LL YD P D+ V +++ + +++ I +
Sbjct: 62 DNITIFTRILDRLLDGYDNRLRPGLGDAVTEVKTDIYVTSFGPVSDTDMEYTIDVFFRQT 121
Query: 280 WIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAXATTXGDYALR---ARVSNNGSVSW 450
W D+RL ++ + + ++W PD N + + R+ +NG++ +
Sbjct: 122 WHDERLKFDGPMKILPLNNLLASKIWTPDTFFHNGKKSVAHNMTTPNKLLRLVDNGTLLY 181
Query: 451 IKRLDISXPISMQLDXWXNDMQTCTFKFG 537
RL I M L+ + D+ C KFG
Sbjct: 182 TMRLTIHAECPMHLEDFPMDVHACPLKFG 210
>X14767-1|CAA32875.1| 474|Homo sapiens GABA-A receptor beta 1
subunit protein.
Length = 474
Score = 41.5 bits (93), Expect = 0.004
Identities = 38/167 (22%), Positives = 69/167 (41%), Gaps = 9/167 (5%)
Frame = +1
Query: 58 IILLPFLLT--CAIASAAECENATSLSLMIDSLLATYDRDSPPD---SKIVVNLTLHLRH 222
++ P ++T C S E N + +D LL YD PD + V + + +
Sbjct: 12 LLSFPVMITMVCCAHSTNEPSNMPYVKETVDRLLKGYDIRLRPDFGGPPVDVGMRIDVAS 71
Query: 223 AN-IRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAXATTX 399
+ + E + Q +W DKRLS++ + +++LW PD LN +
Sbjct: 72 IDMVSEVNMDYTLTMYFQQSWKDKRLSYSGIPLNLTLDNRVADQLWVPDTYFLNDKKSFV 131
Query: 400 GDYALR---ARVSNNGSVSWIKRLDISXPISMQLDXWXNDMQTCTFK 531
++ R+ +G+V + R+ + M L + D Q CT +
Sbjct: 132 HGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLE 178
>BC109211-1|AAI09212.1| 632|Homo sapiens gamma-aminobutyric acid
(GABA) receptor, theta protein.
Length = 632
Score = 41.5 bits (93), Expect = 0.004
Identities = 34/145 (23%), Positives = 59/145 (40%), Gaps = 7/145 (4%)
Frame = +1
Query: 109 CENATSLSLMIDSLLATYDRDSPPD---SKIVVNLTLHLRHAN-IRESESTVRIQADLQM 276
C N + ++D +L+ YD P+ + + V +++++ I E I
Sbjct: 53 CANEAVVQKILDRVLSRYDVRLRPNFGGAPVPVRISIYVTSIEQISEMNMDYTITMFFHQ 112
Query: 277 NWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAXATTXGDYALRARVSN---NGSVS 447
W D RL++ + E+LW PD LN+ D + RV +G+V
Sbjct: 113 TWKDSRLAYYETTLNLTLDYRMHEKLWVPDCYFLNSKDAFVHDVTVENRVFQLHPDGTVR 172
Query: 448 WIKRLDISXPISMQLDXWXNDMQTC 522
+ RL + S+ L + D Q C
Sbjct: 173 YGIRLTTTAACSLDLHKFPMDKQAC 197
>BC109210-1|AAI09211.1| 632|Homo sapiens gamma-aminobutyric acid
(GABA) receptor, theta protein.
Length = 632
Score = 41.5 bits (93), Expect = 0.004
Identities = 34/145 (23%), Positives = 59/145 (40%), Gaps = 7/145 (4%)
Frame = +1
Query: 109 CENATSLSLMIDSLLATYDRDSPPD---SKIVVNLTLHLRHAN-IRESESTVRIQADLQM 276
C N + ++D +L+ YD P+ + + V +++++ I E I
Sbjct: 53 CANEAVVQKILDRVLSRYDVRLRPNFGGAPVPVRISIYVTSIEQISEMNMDYTITMFFHQ 112
Query: 277 NWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAXATTXGDYALRARVSN---NGSVS 447
W D RL++ + E+LW PD LN+ D + RV +G+V
Sbjct: 113 TWKDSRLAYYETTLNLTLDYRMHEKLWVPDCYFLNSKDAFVHDVTVENRVFQLHPDGTVR 172
Query: 448 WIKRLDISXPISMQLDXWXNDMQTC 522
+ RL + S+ L + D Q C
Sbjct: 173 YGIRLTTTAACSLDLHKFPMDKQAC 197
>AF189259-1|AAF70380.1| 632|Homo sapiens GABA-A receptor theta
subunit protein.
Length = 632
Score = 41.5 bits (93), Expect = 0.004
Identities = 34/145 (23%), Positives = 59/145 (40%), Gaps = 7/145 (4%)
Frame = +1
Query: 109 CENATSLSLMIDSLLATYDRDSPPD---SKIVVNLTLHLRHAN-IRESESTVRIQADLQM 276
C N + ++D +L+ YD P+ + + V +++++ I E I
Sbjct: 53 CANEAVVQKILDRVLSRYDVRLRPNFGGAPVPVRISIYVTSIEQISEMNMDYTITMFFHQ 112
Query: 277 NWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAXATTXGDYALRARVSN---NGSVS 447
W D RL++ + E+LW PD LN+ D + RV +G+V
Sbjct: 113 TWKDSRLAYYETTLNLTLDYRMHEKLWVPDCYFLNSKDAFVHDVTVENRVFQLHPDGTVR 172
Query: 448 WIKRLDISXPISMQLDXWXNDMQTC 522
+ RL + S+ L + D Q C
Sbjct: 173 YGIRLTTTAACSLDLHKFPMDKQAC 197
>AF144648-1|AAD51172.1| 627|Homo sapiens GABA-A receptor theta
protein.
Length = 627
Score = 41.5 bits (93), Expect = 0.004
Identities = 34/145 (23%), Positives = 59/145 (40%), Gaps = 7/145 (4%)
Frame = +1
Query: 109 CENATSLSLMIDSLLATYDRDSPPD---SKIVVNLTLHLRHAN-IRESESTVRIQADLQM 276
C N + ++D +L+ YD P+ + + V +++++ I E I
Sbjct: 48 CANEAVVQKILDRVLSRYDVRLRPNFGGAPVPVRISIYVTSIEQISEMNMDYTITMFFHQ 107
Query: 277 NWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAXATTXGDYALRARVSN---NGSVS 447
W D RL++ + E+LW PD LN+ D + RV +G+V
Sbjct: 108 TWKDSRLAYYETTLNLTLDYRMHEKLWVPDCYFLNSKDAFVHDVTVENRVFQLHPDGTVR 167
Query: 448 WIKRLDISXPISMQLDXWXNDMQTC 522
+ RL + S+ L + D Q C
Sbjct: 168 YGIRLTTTAACSLDLHKFPMDKQAC 192
>BC033801-1|AAH33801.1| 452|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, delta protein.
Length = 452
Score = 40.7 bits (91), Expect = 0.007
Identities = 35/135 (25%), Positives = 57/135 (42%), Gaps = 7/135 (5%)
Frame = +1
Query: 139 IDSLLATYDRDSPPD-SKIVVNLTLHLRHANI---RESESTVRIQADLQMNWIDKRLSWN 306
+D L+A Y R+ P VN+ L L A+I E+ + L +W D RLS+N
Sbjct: 44 LDGLIAGYARNFRPGIGGPPVNVALALEVASIDHISEANMEYTMTVFLHQSWRDSRLSYN 103
Query: 307 AGEWGCSTWLVSSERLWRPDVVLLNAXATTXGDYALR---ARVSNNGSVSWIKRLDISXP 477
++LW PD ++NA + D + R+ +G + + R+ +
Sbjct: 104 HTNETLGLDSRFVDKLWLPDTFIVNAKSAWFHDVTVENKLIRLQPDGVILYSIRITSTVA 163
Query: 478 ISMQLDXWXNDMQTC 522
M L + D Q C
Sbjct: 164 CDMDLAKYPMDEQEC 178
>AL391845-4|CAI15436.1| 452|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, delta protein.
Length = 452
Score = 40.7 bits (91), Expect = 0.007
Identities = 35/135 (25%), Positives = 57/135 (42%), Gaps = 7/135 (5%)
Frame = +1
Query: 139 IDSLLATYDRDSPPD-SKIVVNLTLHLRHANI---RESESTVRIQADLQMNWIDKRLSWN 306
+D L+A Y R+ P VN+ L L A+I E+ + L +W D RLS+N
Sbjct: 44 LDGLIAGYARNFRPGIGGPPVNVALALEVASIDHISEANMEYTMTVFLHQSWRDSRLSYN 103
Query: 307 AGEWGCSTWLVSSERLWRPDVVLLNAXATTXGDYALR---ARVSNNGSVSWIKRLDISXP 477
++LW PD ++NA + D + R+ +G + + R+ +
Sbjct: 104 HTNETLGLDSRFVDKLWLPDTFIVNAKSAWFHDVTVENKLIRLQPDGVILYSIRITSTVA 163
Query: 478 ISMQLDXWXNDMQTC 522
M L + D Q C
Sbjct: 164 CDMDLAKYPMDEQEC 178
>AF016917-1|AAB70007.1| 452|Homo sapiens GABA-A receptor delta
subunit protein.
Length = 452
Score = 40.7 bits (91), Expect = 0.007
Identities = 35/135 (25%), Positives = 57/135 (42%), Gaps = 7/135 (5%)
Frame = +1
Query: 139 IDSLLATYDRDSPPD-SKIVVNLTLHLRHANI---RESESTVRIQADLQMNWIDKRLSWN 306
+D L+A Y R+ P VN+ L L A+I E+ + L +W D RLS+N
Sbjct: 44 LDGLIAGYARNFRPGIGGPPVNVALALEVASIDHISEANMEYTMTVFLHQSWRDSRLSYN 103
Query: 307 AGEWGCSTWLVSSERLWRPDVVLLNAXATTXGDYALR---ARVSNNGSVSWIKRLDISXP 477
++LW PD ++NA + D + R+ +G + + R+ +
Sbjct: 104 HTNETLGLDSRFVDKLWLPDTFIVNAKSAWFHDVTVENKLIRLQPDGVILYSIRITSTVA 163
Query: 478 ISMQLDXWXNDMQTC 522
M L + D Q C
Sbjct: 164 CDMDLAKYPMDEQEC 178
>U30461-1|AAB52519.1| 554|Homo sapiens GABAA receptor subunit
alpha4 protein.
Length = 554
Score = 39.1 bits (87), Expect = 0.021
Identities = 34/142 (23%), Positives = 59/142 (41%), Gaps = 8/142 (5%)
Frame = +1
Query: 136 MIDSLLATYD-RDSP----PDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLS 300
++DSLL YD R P P +++ ++ + + + E + + WIDKRL
Sbjct: 51 ILDSLLDGYDNRLRPGFGGPVTEVKTDIYV-TSFGPVSDVEMEYTMDVFFRQTWIDKRLK 109
Query: 301 WNAGEWGCSTWLVSSERLWRPDVVLLNAXATTXGDYALRA---RVSNNGSVSWIKRLDIS 471
++ + ++W PD N + + R+ NG++ + RL IS
Sbjct: 110 YDGPIEILRLNNMMVTKVWTPDTFFRNGKKSVSHNMTAPNKLFRIMRNGTILYTMRLTIS 169
Query: 472 XPISMQLDXWXNDMQTCTFKFG 537
M+L + D C KFG
Sbjct: 170 AECPMRLVDFPMDGHACPLKFG 191
>BC035055-1|AAH35055.1| 554|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 4 protein.
Length = 554
Score = 39.1 bits (87), Expect = 0.021
Identities = 34/142 (23%), Positives = 59/142 (41%), Gaps = 8/142 (5%)
Frame = +1
Query: 136 MIDSLLATYD-RDSP----PDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLS 300
++DSLL YD R P P +++ ++ + + + E + + WIDKRL
Sbjct: 51 ILDSLLDGYDNRLRPGFGGPVTEVKTDIYV-TSFGPVSDVEMEYTMDVFFRQTWIDKRLK 109
Query: 301 WNAGEWGCSTWLVSSERLWRPDVVLLNAXATTXGDYALRA---RVSNNGSVSWIKRLDIS 471
++ + ++W PD N + + R+ NG++ + RL IS
Sbjct: 110 YDGPIEILRLNNMMVTKVWTPDTFFRNGKKSVSHNMTAPNKLFRIMRNGTILYTMRLTIS 169
Query: 472 XPISMQLDXWXNDMQTCTFKFG 537
M+L + D C KFG
Sbjct: 170 AECPMRLVDFPMDGHACPLKFG 191
>U93917-1|AAC39917.1| 449|Homo sapiens glycine receptor alpha 3
subunit protein.
Length = 449
Score = 38.7 bits (86), Expect = 0.027
Identities = 41/165 (24%), Positives = 68/165 (41%), Gaps = 11/165 (6%)
Frame = +1
Query: 61 ILLPFLLTCAIASAAECENATSLSLMIDSLLAT---YDRDSPPDSK-IVVNLTLHL---R 219
+LL + T SA S S +D L+ YD P+ K VN+T ++
Sbjct: 21 LLLSLVATKETDSARSRSAPMSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINS 80
Query: 220 HANIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERLWRPDVVLLNAXATT 396
+I E+ R+ L+ W D RL+++ S + +W+PD+ N
Sbjct: 81 FGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGAN 140
Query: 397 XGDYALR---ARVSNNGSVSWIKRLDISXPISMQLDXWXNDMQTC 522
+ R+ NG+V + RL ++ M L + D+QTC
Sbjct: 141 FHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFPMDVQTC 185
>BC114947-1|AAI14948.1| 457|Homo sapiens GLRA1 protein protein.
Length = 457
Score = 38.7 bits (86), Expect = 0.027
Identities = 42/179 (23%), Positives = 77/179 (43%), Gaps = 17/179 (9%)
Frame = +1
Query: 37 HKMSTTYIILLPFLLTCAIASAAECENATSL------SLMIDSLLAT---YDRDSPPDSK 189
+ +T + L ++ ++A++ E E A S S +D L+ YD P+ K
Sbjct: 2 YSFNTLRLYLWETIVFFSLAASKEAEAARSAPKPMSPSDFLDKLMGRTSGYDARIRPNFK 61
Query: 190 -IVVNLTLHL---RHANIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERL 354
VN++ ++ +I E+ R+ L+ W D RL++N S + +
Sbjct: 62 GPPVNVSCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYNEYPDDSLDLDPSMLDSI 121
Query: 355 WRPDVVLLNAXATTXGDYALR---ARVSNNGSVSWIKRLDISXPISMQLDXWXNDMQTC 522
W+PD+ N + R+S NG+V + R+ ++ M L + D+QTC
Sbjct: 122 WKPDLFFANEKGAHFHEITTDNKLLRISRNGNVLYSIRITLTLACPMDLKNFPMDVQTC 180
>BC074980-1|AAH74980.1| 449|Homo sapiens glycine receptor, alpha 1
(startle disease/hyperekplexia) protein.
Length = 449
Score = 38.7 bits (86), Expect = 0.027
Identities = 42/179 (23%), Positives = 77/179 (43%), Gaps = 17/179 (9%)
Frame = +1
Query: 37 HKMSTTYIILLPFLLTCAIASAAECENATSL------SLMIDSLLAT---YDRDSPPDSK 189
+ +T + L ++ ++A++ E E A S S +D L+ YD P+ K
Sbjct: 2 YSFNTLRLYLWETIVFFSLAASKEAEAARSAPKPMSPSDFLDKLMGRTSGYDARIRPNFK 61
Query: 190 -IVVNLTLHL---RHANIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERL 354
VN++ ++ +I E+ R+ L+ W D RL++N S + +
Sbjct: 62 GPPVNVSCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYNEYPDDSLDLDPSMLDSI 121
Query: 355 WRPDVVLLNAXATTXGDYALR---ARVSNNGSVSWIKRLDISXPISMQLDXWXNDMQTC 522
W+PD+ N + R+S NG+V + R+ ++ M L + D+QTC
Sbjct: 122 WKPDLFFANEKGAHFHEITTDNKLLRISRNGNVLYSIRITLTLACPMDLKNFPMDVQTC 180
>BC036086-1|AAH36086.1| 464|Homo sapiens glycine receptor, alpha 3
protein.
Length = 464
Score = 38.7 bits (86), Expect = 0.027
Identities = 41/165 (24%), Positives = 68/165 (41%), Gaps = 11/165 (6%)
Frame = +1
Query: 61 ILLPFLLTCAIASAAECENATSLSLMIDSLLAT---YDRDSPPDSK-IVVNLTLHL---R 219
+LL + T SA S S +D L+ YD P+ K VN+T ++
Sbjct: 21 LLLSLVATKETDSARSRSAPMSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINS 80
Query: 220 HANIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERLWRPDVVLLNAXATT 396
+I E+ R+ L+ W D RL+++ S + +W+PD+ N
Sbjct: 81 FGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGAN 140
Query: 397 XGDYALR---ARVSNNGSVSWIKRLDISXPISMQLDXWXNDMQTC 522
+ R+ NG+V + RL ++ M L + D+QTC
Sbjct: 141 FHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFPMDVQTC 185
>AF017724-1|AAC39919.1| 465|Homo sapiens glycine receptor alpha 3
subunit protein.
Length = 465
Score = 38.7 bits (86), Expect = 0.027
Identities = 41/165 (24%), Positives = 68/165 (41%), Gaps = 11/165 (6%)
Frame = +1
Query: 61 ILLPFLLTCAIASAAECENATSLSLMIDSLLAT---YDRDSPPDSK-IVVNLTLHL---R 219
+LL + T SA S S +D L+ YD P+ K VN+T ++
Sbjct: 21 LLLSLVATKETDSARSRSAPMSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINS 80
Query: 220 HANIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERLWRPDVVLLNAXATT 396
+I E+ R+ L+ W D RL+++ S + +W+PD+ N
Sbjct: 81 FGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGAN 140
Query: 397 XGDYALR---ARVSNNGSVSWIKRLDISXPISMQLDXWXNDMQTC 522
+ R+ NG+V + RL ++ M L + D+QTC
Sbjct: 141 FHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFPMDVQTC 185
>X52009-1|CAA36258.1| 449|Homo sapiens inhibitory glycine receptor
protein.
Length = 449
Score = 38.3 bits (85), Expect = 0.036
Identities = 26/103 (25%), Positives = 45/103 (43%), Gaps = 4/103 (3%)
Frame = +1
Query: 226 NIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERLWRPDVVLLNAXATTXG 402
+I E+ R+ L+ W D RL++N S + +W+PD+ N
Sbjct: 78 SIAETTMDYRVNIFLRQQWNDPRLAYNEYPDDSLDLDPSMLDSIWKPDLFFANEKGAHFH 137
Query: 403 DYALR---ARVSNNGSVSWIKRLDISXPISMQLDXWXNDMQTC 522
+ R+S NG+V + R+ ++ M L + D+QTC
Sbjct: 138 EITTDNKLLRISRNGNVLYSIRITLTLACPMDLKNFPMDVQTC 180
>U95367-1|AAC51357.1| 440|Homo sapiens GABA-A receptor pi subunit
protein.
Length = 440
Score = 38.3 bits (85), Expect = 0.036
Identities = 37/148 (25%), Positives = 68/148 (45%), Gaps = 9/148 (6%)
Frame = +1
Query: 106 ECENATSLSLM-IDSLLATYDRDSPPD---SKIVVNLTLHLRH-ANIRESESTVRIQADL 270
E + LSL ++L A Y++ P+ + + LTL + ++I ES L
Sbjct: 29 EVGRSDKLSLPGFENLTAGYNKFLRPNFGGEPVQIALTLDIASISSISESNMDYTATIYL 88
Query: 271 QMNWIDKRLSWNAGE-WGCSTWLVSSERLWRPDVVLLNAXATTXGDYALR---ARVSNNG 438
+ W+D+RL + + + LV E LW PD ++ + + + + R+ +NG
Sbjct: 89 RQRWMDQRLVFEGNKSFTLDARLV--EFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNG 146
Query: 439 SVSWIKRLDISXPISMQLDXWXNDMQTC 522
+V + R+ + +M L + D QTC
Sbjct: 147 TVLYALRITTTVACNMDLSKYPMDTQTC 174
>BC109106-1|AAI09107.1| 440|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, pi protein.
Length = 440
Score = 38.3 bits (85), Expect = 0.036
Identities = 37/148 (25%), Positives = 68/148 (45%), Gaps = 9/148 (6%)
Frame = +1
Query: 106 ECENATSLSLM-IDSLLATYDRDSPPD---SKIVVNLTLHLRH-ANIRESESTVRIQADL 270
E + LSL ++L A Y++ P+ + + LTL + ++I ES L
Sbjct: 29 EVGRSDKLSLPGFENLTAGYNKFLRPNFGGEPVQIALTLDIASISSISESNMDYTATIYL 88
Query: 271 QMNWIDKRLSWNAGE-WGCSTWLVSSERLWRPDVVLLNAXATTXGDYALR---ARVSNNG 438
+ W+D+RL + + + LV E LW PD ++ + + + + R+ +NG
Sbjct: 89 RQRWMDQRLVFEGNKSFTLDARLV--EFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNG 146
Query: 439 SVSWIKRLDISXPISMQLDXWXNDMQTC 522
+V + R+ + +M L + D QTC
Sbjct: 147 TVLYALRITTTVACNMDLSKYPMDTQTC 174
>BC109105-1|AAI09106.1| 440|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, pi protein.
Length = 440
Score = 38.3 bits (85), Expect = 0.036
Identities = 37/148 (25%), Positives = 68/148 (45%), Gaps = 9/148 (6%)
Frame = +1
Query: 106 ECENATSLSLM-IDSLLATYDRDSPPD---SKIVVNLTLHLRH-ANIRESESTVRIQADL 270
E + LSL ++L A Y++ P+ + + LTL + ++I ES L
Sbjct: 29 EVGRSDKLSLPGFENLTAGYNKFLRPNFGGEPVQIALTLDIASISSISESNMDYTATIYL 88
Query: 271 QMNWIDKRLSWNAGE-WGCSTWLVSSERLWRPDVVLLNAXATTXGDYALR---ARVSNNG 438
+ W+D+RL + + + LV E LW PD ++ + + + + R+ +NG
Sbjct: 89 RQRWMDQRLVFEGNKSFTLDARLV--EFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNG 146
Query: 439 SVSWIKRLDISXPISMQLDXWXNDMQTC 522
+V + R+ + +M L + D QTC
Sbjct: 147 TVLYALRITTTVACNMDLSKYPMDTQTC 174
>BC074865-1|AAH74865.1| 440|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, pi protein.
Length = 440
Score = 38.3 bits (85), Expect = 0.036
Identities = 37/148 (25%), Positives = 68/148 (45%), Gaps = 9/148 (6%)
Frame = +1
Query: 106 ECENATSLSLM-IDSLLATYDRDSPPD---SKIVVNLTLHLRH-ANIRESESTVRIQADL 270
E + LSL ++L A Y++ P+ + + LTL + ++I ES L
Sbjct: 29 EVGRSDKLSLPGFENLTAGYNKFLRPNFGGEPVQIALTLDIASISSISESNMDYTATIYL 88
Query: 271 QMNWIDKRLSWNAGE-WGCSTWLVSSERLWRPDVVLLNAXATTXGDYALR---ARVSNNG 438
+ W+D+RL + + + LV E LW PD ++ + + + + R+ +NG
Sbjct: 89 RQRWMDQRLVFEGNKSFTLDARLV--EFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNG 146
Query: 439 SVSWIKRLDISXPISMQLDXWXNDMQTC 522
+V + R+ + +M L + D QTC
Sbjct: 147 TVLYALRITTTVACNMDLSKYPMDTQTC 174
>BC074810-1|AAH74810.1| 440|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, pi protein.
Length = 440
Score = 38.3 bits (85), Expect = 0.036
Identities = 37/148 (25%), Positives = 68/148 (45%), Gaps = 9/148 (6%)
Frame = +1
Query: 106 ECENATSLSLM-IDSLLATYDRDSPPD---SKIVVNLTLHLRH-ANIRESESTVRIQADL 270
E + LSL ++L A Y++ P+ + + LTL + ++I ES L
Sbjct: 29 EVGRSDKLSLPGFENLTAGYNKFLRPNFGGEPVQIALTLDIASISSISESNMDYTATIYL 88
Query: 271 QMNWIDKRLSWNAGE-WGCSTWLVSSERLWRPDVVLLNAXATTXGDYALR---ARVSNNG 438
+ W+D+RL + + + LV E LW PD ++ + + + + R+ +NG
Sbjct: 89 RQRWMDQRLVFEGNKSFTLDARLV--EFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNG 146
Query: 439 SVSWIKRLDISXPISMQLDXWXNDMQTC 522
+V + R+ + +M L + D QTC
Sbjct: 147 TVLYALRITTTVACNMDLSKYPMDTQTC 174
>AF009702-1|AAC24194.1| 440|Homo sapiens GABA-A receptor pi subunit
protein.
Length = 440
Score = 38.3 bits (85), Expect = 0.036
Identities = 37/148 (25%), Positives = 68/148 (45%), Gaps = 9/148 (6%)
Frame = +1
Query: 106 ECENATSLSLM-IDSLLATYDRDSPPD---SKIVVNLTLHLRH-ANIRESESTVRIQADL 270
E + LSL ++L A Y++ P+ + + LTL + ++I ES L
Sbjct: 29 EVGRSDKLSLPGFENLTAGYNKFLRPNFGGEPVQIALTLDIASISSISESNMDYTATIYL 88
Query: 271 QMNWIDKRLSWNAGE-WGCSTWLVSSERLWRPDVVLLNAXATTXGDYALR---ARVSNNG 438
+ W+D+RL + + + LV E LW PD ++ + + + + R+ +NG
Sbjct: 89 RQRWMDQRLVFEGNKSFTLDARLV--EFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNG 146
Query: 439 SVSWIKRLDISXPISMQLDXWXNDMQTC 522
+V + R+ + +M L + D QTC
Sbjct: 147 TVLYALRITTTVACNMDLSKYPMDTQTC 174
>S81944-1|AAB36480.1| 453|Homo sapiens gamma-aminobutyric acid type
A receptor alpha 6 subunit protein.
Length = 453
Score = 37.9 bits (84), Expect = 0.048
Identities = 31/145 (21%), Positives = 58/145 (40%), Gaps = 7/145 (4%)
Frame = +1
Query: 124 SLSLMIDSLLATYDRDSPPD---SKIVVNLTLHLRHAN-IRESESTVRIQADLQMNWIDK 291
++S ++D+LL YD P + V +++ + + E + + W D+
Sbjct: 31 NVSRILDNLLEGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTDE 90
Query: 292 RLSWNAGEWGCSTWLVSSERLWRPDVVLLNAXATTXGDYALRA---RVSNNGSVSWIKRL 462
RL + S + ++W PD N + + R+ NG++ + RL
Sbjct: 91 RLKFGGPTEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTMRL 150
Query: 463 DISXPISMQLDXWXNDMQTCTFKFG 537
I+ M+L + D C KFG
Sbjct: 151 TINADCPMRLVNFPMDGHACPLKFG 175
>BC099641-1|AAH99641.1| 453|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 6 protein.
Length = 453
Score = 37.9 bits (84), Expect = 0.048
Identities = 31/145 (21%), Positives = 58/145 (40%), Gaps = 7/145 (4%)
Frame = +1
Query: 124 SLSLMIDSLLATYDRDSPPD---SKIVVNLTLHLRHAN-IRESESTVRIQADLQMNWIDK 291
++S ++D+LL YD P + V +++ + + E + + W D+
Sbjct: 31 NVSRILDNLLEGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTDE 90
Query: 292 RLSWNAGEWGCSTWLVSSERLWRPDVVLLNAXATTXGDYALRA---RVSNNGSVSWIKRL 462
RL + S + ++W PD N + + R+ NG++ + RL
Sbjct: 91 RLKFGGPTEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTMRL 150
Query: 463 DISXPISMQLDXWXNDMQTCTFKFG 537
I+ M+L + D C KFG
Sbjct: 151 TINADCPMRLVNFPMDGHACPLKFG 175
>BC099640-1|AAH99640.1| 453|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 6 protein.
Length = 453
Score = 37.9 bits (84), Expect = 0.048
Identities = 31/145 (21%), Positives = 58/145 (40%), Gaps = 7/145 (4%)
Frame = +1
Query: 124 SLSLMIDSLLATYDRDSPPD---SKIVVNLTLHLRHAN-IRESESTVRIQADLQMNWIDK 291
++S ++D+LL YD P + V +++ + + E + + W D+
Sbjct: 31 NVSRILDNLLEGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTDE 90
Query: 292 RLSWNAGEWGCSTWLVSSERLWRPDVVLLNAXATTXGDYALRA---RVSNNGSVSWIKRL 462
RL + S + ++W PD N + + R+ NG++ + RL
Sbjct: 91 RLKFGGPTEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTMRL 150
Query: 463 DISXPISMQLDXWXNDMQTCTFKFG 537
I+ M+L + D C KFG
Sbjct: 151 TINADCPMRLVNFPMDGHACPLKFG 175
>BC096242-1|AAH96242.1| 453|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 6 protein.
Length = 453
Score = 37.9 bits (84), Expect = 0.048
Identities = 31/145 (21%), Positives = 58/145 (40%), Gaps = 7/145 (4%)
Frame = +1
Query: 124 SLSLMIDSLLATYDRDSPPD---SKIVVNLTLHLRHAN-IRESESTVRIQADLQMNWIDK 291
++S ++D+LL YD P + V +++ + + E + + W D+
Sbjct: 31 NVSRILDNLLEGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTDE 90
Query: 292 RLSWNAGEWGCSTWLVSSERLWRPDVVLLNAXATTXGDYALRA---RVSNNGSVSWIKRL 462
RL + S + ++W PD N + + R+ NG++ + RL
Sbjct: 91 RLKFGGPTEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTMRL 150
Query: 463 DISXPISMQLDXWXNDMQTCTFKFG 537
I+ M+L + D C KFG
Sbjct: 151 TINADCPMRLVNFPMDGHACPLKFG 175
>BC096241-1|AAH96241.1| 453|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 6 protein.
Length = 453
Score = 37.9 bits (84), Expect = 0.048
Identities = 31/145 (21%), Positives = 58/145 (40%), Gaps = 7/145 (4%)
Frame = +1
Query: 124 SLSLMIDSLLATYDRDSPPD---SKIVVNLTLHLRHAN-IRESESTVRIQADLQMNWIDK 291
++S ++D+LL YD P + V +++ + + E + + W D+
Sbjct: 31 NVSRILDNLLEGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTDE 90
Query: 292 RLSWNAGEWGCSTWLVSSERLWRPDVVLLNAXATTXGDYALRA---RVSNNGSVSWIKRL 462
RL + S + ++W PD N + + R+ NG++ + RL
Sbjct: 91 RLKFGGPTEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTMRL 150
Query: 463 DISXPISMQLDXWXNDMQTCTFKFG 537
I+ M+L + D C KFG
Sbjct: 151 TINADCPMRLVNFPMDGHACPLKFG 175
>Z93848-1|CAI41994.1| 376|Homo sapiens glycine receptor, alpha 4
protein.
Length = 376
Score = 37.1 bits (82), Expect = 0.083
Identities = 28/122 (22%), Positives = 51/122 (41%), Gaps = 4/122 (3%)
Frame = +1
Query: 178 PDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERL 354
P + N+ ++ ++I ++ R+ L+ W D RLS+ S + +
Sbjct: 28 PPVNVTCNIFIN-SFSSITKTTMDYRVNVFLRQQWNDPRLSYREYPDDSLDLDPSMLDSI 86
Query: 355 WRPDVVLLNAXATTXGDYALR---ARVSNNGSVSWIKRLDISXPISMQLDXWXNDMQTCT 525
W+PD+ N + R+ NG+V + RL + M L + D+QTCT
Sbjct: 87 WKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLILSCLMDLKNFPMDIQTCT 146
Query: 526 FK 531
+
Sbjct: 147 MQ 148
>BC022449-1|AAH22449.1| 474|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, beta 1 protein.
Length = 474
Score = 37.1 bits (82), Expect = 0.083
Identities = 37/167 (22%), Positives = 69/167 (41%), Gaps = 9/167 (5%)
Frame = +1
Query: 58 IILLPFLLT--CAIASAAECENATSLSLMIDSLLATYDRDSPPD---SKIVVNLTLHLRH 222
++ P ++T C S E N + + +D LL YD PD + V + + +
Sbjct: 12 LLSFPVMITMVCCAHSTNEPSNMSYVKETVDRLLKGYDIRLRPDFGGPPVDVGMRIDVAS 71
Query: 223 AN-IRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAXATTX 399
+ + E + Q +W DKRLS++ + +++L PD LN +
Sbjct: 72 IDMVSEVNMDYTLTMYFQQSWKDKRLSYSGIPLNLTLDNRVADQLCVPDTYFLNDKKSFV 131
Query: 400 GDYALR---ARVSNNGSVSWIKRLDISXPISMQLDXWXNDMQTCTFK 531
++ R+ +G+V + R+ + M L + D Q CT +
Sbjct: 132 HGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLE 178
>AL049610-1|CAI42158.1| 376|Homo sapiens glycine receptor, alpha 4
protein.
Length = 376
Score = 37.1 bits (82), Expect = 0.083
Identities = 28/122 (22%), Positives = 51/122 (41%), Gaps = 4/122 (3%)
Frame = +1
Query: 178 PDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERL 354
P + N+ ++ ++I ++ R+ L+ W D RLS+ S + +
Sbjct: 28 PPVNVTCNIFIN-SFSSITKTTMDYRVNVFLRQQWNDPRLSYREYPDDSLDLDPSMLDSI 86
Query: 355 WRPDVVLLNAXATTXGDYALR---ARVSNNGSVSWIKRLDISXPISMQLDXWXNDMQTCT 525
W+PD+ N + R+ NG+V + RL + M L + D+QTCT
Sbjct: 87 WKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLILSCLMDLKNFPMDIQTCT 146
Query: 526 FK 531
+
Sbjct: 147 MQ 148
>BC114967-1|AAI14968.1| 366|Homo sapiens GLRA1 protein protein.
Length = 366
Score = 35.9 bits (79), Expect = 0.19
Identities = 24/94 (25%), Positives = 41/94 (43%), Gaps = 4/94 (4%)
Frame = +1
Query: 253 RIQADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERLWRPDVVLLNAXATTXGDYALR---A 420
R+ L+ W D RL++N S + +W+PD+ N +
Sbjct: 4 RVNIFLRQQWNDPRLAYNEYPDDSLDLDPSMLDSIWKPDLFFANEKGAHFHEITTDNKLL 63
Query: 421 RVSNNGSVSWIKRLDISXPISMQLDXWXNDMQTC 522
R+S NG+V + R+ ++ M L + D+QTC
Sbjct: 64 RISRNGNVLYSIRITLTLACPMDLKNFPMDVQTC 97
>U83981-1|AAC25631.1| 674|Homo sapiens apoptosis associated protein
protein.
Length = 674
Score = 31.5 bits (68), Expect = 4.1
Identities = 17/46 (36%), Positives = 22/46 (47%), Gaps = 1/46 (2%)
Frame = -1
Query: 427 IHGXGERSPRRWLXPRLAVPRQASTSVPRTPAKCCSP-TPLRSNSV 293
I+ GE+ P W PRL + Q P TP P TPL++ V
Sbjct: 511 IYVPGEKPPPPWAPPRLPLRLQRRLKRPETPTHDPDPETPLKARKV 556
>CR457259-1|CAG33540.1| 674|Homo sapiens PPP1R15A protein.
Length = 674
Score = 31.5 bits (68), Expect = 4.1
Identities = 17/46 (36%), Positives = 22/46 (47%), Gaps = 1/46 (2%)
Frame = -1
Query: 427 IHGXGERSPRRWLXPRLAVPRQASTSVPRTPAKCCSP-TPLRSNSV 293
I+ GE+ P W PRL + Q P TP P TPL++ V
Sbjct: 511 IYVPGEKPPPPWAPPRLPLRLQRRLKRPETPTHDPDPETPLKARKV 556
>BC003067-1|AAH03067.1| 674|Homo sapiens protein phosphatase 1,
regulatory (inhibitor) subunit 15A protein.
Length = 674
Score = 31.5 bits (68), Expect = 4.1
Identities = 17/46 (36%), Positives = 22/46 (47%), Gaps = 1/46 (2%)
Frame = -1
Query: 427 IHGXGERSPRRWLXPRLAVPRQASTSVPRTPAKCCSP-TPLRSNSV 293
I+ GE+ P W PRL + Q P TP P TPL++ V
Sbjct: 511 IYVPGEKPPPPWAPPRLPLRLQRRLKRPETPTHDPDPETPLKARKV 556
>AK001361-1|BAA91649.1| 674|Homo sapiens protein ( Homo sapiens
cDNA FLJ10499 fis, clone NT2RP2000346, weakly similar to
MYELOID DIFFERENTIATION PRIMARY RESPONSE PROTEIN MYD116.
).
Length = 674
Score = 31.5 bits (68), Expect = 4.1
Identities = 17/46 (36%), Positives = 22/46 (47%), Gaps = 1/46 (2%)
Frame = -1
Query: 427 IHGXGERSPRRWLXPRLAVPRQASTSVPRTPAKCCSP-TPLRSNSV 293
I+ GE+ P W PRL + Q P TP P TPL++ V
Sbjct: 511 IYVPGEKPPPPWAPPRLPLRLQRRLKRPETPTHDPDPETPLKARKV 556
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 111,364,443
Number of Sequences: 237096
Number of extensions: 2393674
Number of successful extensions: 5280
Number of sequences better than 10.0: 161
Number of HSP's better than 10.0 without gapping: 4907
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5154
length of database: 76,859,062
effective HSP length: 90
effective length of database: 55,520,422
effective search space used: 11159604822
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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