Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BmNP07_FL5_D22
(851 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
AJ306454-1|CAC34819.1| 497|Homo sapiens neuronal nicotinic acet... 71 7e-12
Y08416-1|CAA69693.1| 498|Homo sapiens nicotinic acetylcholine r... 69 3e-11
U62439-1|AAB40117.1| 498|Homo sapiens nicotinic acetylcholine r... 69 3e-11
U48861-1|AAA92123.1| 498|Homo sapiens beta 4 nicotinic acetylch... 69 3e-11
BC096082-1|AAH96082.1| 498|Homo sapiens cholinergic receptor, n... 69 3e-11
BC096080-1|AAH96080.1| 498|Homo sapiens cholinergic receptor, n... 69 3e-11
AF306329-1|AAL02062.1| 498|Homo sapiens neuronal nicotinic acet... 69 3e-11
Y08417-1|CAA69694.1| 458|Homo sapiens nicotinic acetylcholine r... 65 4e-10
X67513-1|CAA47851.1| 423|Homo sapiens nicotinic acetylcholine ... 65 4e-10
U62438-1|AAB40116.1| 458|Homo sapiens nicotinic acetylcholine r... 65 4e-10
BC069788-1|AAH69788.1| 458|Homo sapiens cholinergic receptor, n... 65 4e-10
BC069703-1|AAH69703.1| 458|Homo sapiens cholinergic receptor, n... 65 4e-10
BC069681-1|AAH69681.1| 458|Homo sapiens cholinergic receptor, n... 65 4e-10
AF140765-1|AAD33063.1| 458|Homo sapiens neuronal acetylcholine ... 65 4e-10
X68275-1|CAA48336.1| 451|Homo sapiens nicotinic receptor beta 4... 64 5e-10
Y08419-1|CAA69696.1| 468|Homo sapiens nicotinic acetylcholine r... 64 6e-10
X14830-1|CAA32939.1| 501|Homo sapiens protein ( Human mRNA for ... 64 6e-10
U62434-1|AAB40112.1| 468|Homo sapiens nicotinic acetylcholine r... 64 6e-10
BC033639-1|AAH33639.1| 468|Homo sapiens cholinergic receptor, n... 64 6e-10
BC011371-1|AAH11371.1| 501|Homo sapiens cholinergic receptor, n... 64 6e-10
AJ306481-1|CAC34820.1| 468|Homo sapiens neuronal nicotinic acet... 64 6e-10
Y16281-1|CAA76154.1| 529|Homo sapiens nicotinic acetylcholine r... 64 8e-10
U62431-1|AAB40109.1| 529|Homo sapiens nicotinic acetylcholine r... 64 8e-10
Y16282-1|CAA76155.1| 494|Homo sapiens nicotinic acetylcholine r... 63 1e-09
Y08418-1|CAA69695.1| 503|Homo sapiens nicotinic acetylcholine r... 63 1e-09
X53559-1|CAA37625.1| 474|Homo sapiens neuronal nicotinic acetyl... 63 1e-09
U62435-1|AAB40113.1| 494|Homo sapiens nicotinic acetylcholine r... 63 1e-09
U62432-1|AAB40110.1| 504|Homo sapiens nicotinic acetylcholine r... 63 1e-09
M37981-1|AAA59942.1| 503|Homo sapiens neuronal nicotinic acetyl... 63 1e-09
BT006897-1|AAP35543.1| 505|Homo sapiens cholinergic receptor, n... 63 1e-09
BT006646-1|AAP35292.1| 489|Homo sapiens cholinergic receptor, n... 63 1e-09
BC098443-1|AAH98443.1| 504|Homo sapiens cholinergic receptor, n... 63 1e-09
BC014456-1|AAH14456.1| 494|Homo sapiens cholinergic receptor, n... 63 1e-09
BC006114-1|AAH06114.1| 489|Homo sapiens CHRNA3 protein protein. 63 1e-09
BC002996-1|AAH02996.1| 505|Homo sapiens cholinergic receptor, n... 63 1e-09
BC001642-1|AAH01642.1| 505|Homo sapiens cholinergic receptor, n... 63 1e-09
BC000513-1|AAH00513.1| 505|Homo sapiens cholinergic receptor, n... 63 1e-09
AJ007783-1|CAA07682.1| 504|Homo sapiens nicotinic acetylcholine... 63 1e-09
AF385584-1|AAK68110.1| 489|Homo sapiens nicotinic cholinergic r... 63 1e-09
AB079251-1|BAC06855.1| 494|Homo sapiens Nicotinic acetylcholine... 63 1e-09
M83712-1|AAA58357.1| 468|Homo sapiens nicotinic receptor alpha ... 63 1e-09
BC023553-1|AAH23553.1| 501|Homo sapiens cholinergic receptor, n... 63 1e-09
X66403-1|CAA47030.1| 493|Homo sapiens acetylcholine receptor ep... 62 2e-09
AF105999-1|AAD24503.1| 493|Homo sapiens acetylcholine receptor ... 62 2e-09
Y08421-1|CAA69698.1| 627|Homo sapiens nicotinic acetylcholine r... 61 6e-09
X89741-1|CAA61893.1| 627|Homo sapiens neuronal acetylcholine re... 61 6e-09
X87629-1|CAA60959.1| 602|Homo sapiens nicotinic acetylcholine r... 61 6e-09
U62433-1|AAB40111.1| 627|Homo sapiens nicotinic acetylcholine r... 61 6e-09
M86383-1|AAC84176.1| 502|Homo sapiens nicotinic acetylcholine r... 61 6e-09
L35901-1|AAA64743.1| 627|Homo sapiens nicotinic acetylcholine r... 61 6e-09
DQ093071-1|AAY88737.1| 627|Homo sapiens cholinergic receptor, n... 61 6e-09
BC096290-1|AAH96290.1| 627|Homo sapiens cholinergic receptor, n... 61 6e-09
BC113575-1|AAI13576.1| 479|Homo sapiens cholinergic receptor, n... 60 1e-08
BC113549-1|AAI13550.1| 479|Homo sapiens cholinergic receptor, n... 60 1e-08
AY123244-1|AAM74523.1| 479|Homo sapiens nicotinic acetylcholine... 60 1e-08
AJ243342-1|CAB65091.1| 479|Homo sapiens nicotinic acetylcholine... 60 1e-08
AC118275-1|AAY40986.1| 479|Homo sapiens unknown protein. 60 1e-08
X01715-1|CAA25861.1| 520|Homo sapiens acetylcholine receptor ga... 60 1e-08
AC092165-3|AAY24103.1| 520|Homo sapiens unknown protein. 60 1e-08
Y00762-1|CAA68731.1| 457|Homo sapiens protein ( Human mRNA for ... 58 3e-08
X02502-1|CAA26344.1| 457|Homo sapiens acetylcholine receptor pr... 58 3e-08
S77094-1|AAD14247.1| 457|Homo sapiens nicotinic acetylcholine r... 58 3e-08
BC006314-1|AAH06314.1| 269|Homo sapiens CHRNA1 protein protein. 58 3e-08
AF227732-1|AAF61920.1| 470|Homo sapiens nicotinic acetylcholine... 58 3e-08
AC018890-1|AAY14687.1| 457|Homo sapiens unknown protein. 58 3e-08
S77554-1|AAB33983.1| 474|Homo sapiens GABAA receptor beta 2 sub... 57 9e-08
S77553-1|AAB33982.1| 512|Homo sapiens GABAA receptor beta 2 sub... 57 9e-08
S67368-1|AAB29370.1| 474|Homo sapiens gamma-aminobutyric acid A... 57 9e-08
BC105639-1|AAI05640.1| 474|Homo sapiens GABRB2 protein protein. 57 9e-08
BC099719-1|AAH99719.1| 474|Homo sapiens GABRB2 protein protein. 57 9e-08
BC099705-1|AAH99705.1| 474|Homo sapiens GABRB2 protein protein. 57 9e-08
AJ001935-1|CAA05108.1| 504|Homo sapiens CHRNB2 protein. 56 1e-07
Y08415-1|CAA69692.1| 502|Homo sapiens nicotinic acetylcholine r... 56 2e-07
X53179-1|CAA37320.1| 502|Homo sapiens precursor peptide (AA -25... 56 2e-07
U62437-1|AAB40115.1| 502|Homo sapiens nicotinic acetylcholine r... 56 2e-07
BC075041-1|AAH75041.1| 502|Homo sapiens cholinergic receptor, n... 56 2e-07
BC075040-1|AAH75040.1| 502|Homo sapiens cholinergic receptor, n... 56 2e-07
AL592078-3|CAI16184.1| 502|Homo sapiens cholinergic receptor, n... 56 2e-07
AF077186-1|AAD45422.1| 502|Homo sapiens neuronal nicotinic acet... 56 2e-07
X55019-1|CAA38759.1| 517|Homo sapiens acetylcholine receptor de... 56 2e-07
DQ644022-1|ABG35128.1| 456|Homo sapiens 5-HT3 receptor subunit ... 56 2e-07
BC101185-1|AAI01186.1| 374|Homo sapiens HTR3E protein protein. 56 2e-07
BC101183-1|AAI01184.1| 471|Homo sapiens 5-hydroxytryptamine (se... 56 2e-07
BC101182-1|AAI01183.1| 471|Homo sapiens 5-hydroxytryptamine (se... 56 2e-07
BC093925-1|AAH93925.1| 517|Homo sapiens cholinergic receptor, n... 56 2e-07
BC093923-1|AAH93923.1| 517|Homo sapiens cholinergic receptor, n... 56 2e-07
AY159813-1|AAO38167.2| 471|Homo sapiens 5-hydroxytryptamine ser... 56 2e-07
AC092165-2|AAY24102.1| 517|Homo sapiens unknown protein. 56 2e-07
AJ295237-1|CAC16144.1| 450|Homo sapiens neuronal nicotinic acet... 55 3e-07
AJ278118-1|CAC20435.1| 450|Homo sapiens neuronal nicotinic acet... 55 3e-07
AF327367-1|AAK14333.1| 450|Homo sapiens nicotinic acetylcholine... 55 3e-07
AF199235-1|AAG00795.2| 450|Homo sapiens nicotinic acetylcholine... 55 3e-07
BC131799-1|AAI31800.1| 447|Homo sapiens 5-hydroxytryptamine (se... 55 4e-07
AF459285-1|AAL66182.1| 447|Homo sapiens 5-hydroxytryptamine rec... 54 5e-07
AY349353-1|AAQ93477.1| 456|Homo sapiens 5-HT3c1 serotonin recep... 54 9e-07
AY349352-1|AAQ93476.1| 441|Homo sapiens 5-HT3c1 serotonin recep... 54 9e-07
BC110597-1|AAI10598.1| 411|Homo sapiens ligand-gated ion channe... 53 2e-06
AF512521-1|AAO20969.1| 411|Homo sapiens ligand-gated ion channe... 53 2e-06
AB223030-1|BAE19924.1| 411|Homo sapiens ligand-gated ion-channe... 52 2e-06
M59216-1|AAA35862.1| 474|Homo sapiens gamma-aminobutyric acid r... 52 3e-06
Z23141-1|CAA80672.1| 479|Homo sapiens cholinergic receptor, nic... 52 4e-06
Y08420-1|CAA69697.1| 502|Homo sapiens nicotinic acetylcholine r... 52 4e-06
X70297-1|CAA49778.1| 502|Homo sapiens neuronal nicotinic acetyl... 52 4e-06
U62436-1|AAB40114.1| 502|Homo sapiens nicotinic acetylcholine r... 52 4e-06
AJ586911-1|CAE52911.1| 502|Homo sapiens nicotinic acetylcholine... 52 4e-06
X14767-1|CAA32875.1| 474|Homo sapiens GABA-A receptor beta 1 su... 51 5e-06
BC111802-1|AAI11803.1| 465|Homo sapiens CHRNG protein protein. 51 5e-06
U40583-1|AAA83561.1| 502|Homo sapiens alpha 7 neuronal nicotini... 50 8e-06
L08485-1|AAA58490.1| 462|Homo sapiens GABA-benzodiazepine recep... 50 8e-06
BT009830-1|AAP88832.1| 462|Homo sapiens gamma-aminobutyric acid... 50 8e-06
BC113422-1|AAI13423.1| 462|Homo sapiens gamma-aminobutyric acid... 50 8e-06
BC111979-1|AAI11980.1| 462|Homo sapiens gamma-aminobutyric acid... 50 8e-06
AF385585-1|AAK68111.1| 502|Homo sapiens nicotinic cholinergic r... 50 8e-06
AK122638-1|BAC85499.1| 266|Homo sapiens yte protein of 76kDa) (... 50 1e-05
BC028629-1|AAH28629.1| 492|Homo sapiens gamma-aminobutyric acid... 49 2e-05
S62908-1|AAB27279.1| 492|Homo sapiens gamma-aminobutyric acidA ... 49 2e-05
AF166361-1|AAG12455.1| 492|Homo sapiens GABA receptor subunit a... 49 2e-05
BC022449-1|AAH22449.1| 474|Homo sapiens gamma-aminobutyric acid... 47 1e-04
BC109211-1|AAI09212.1| 632|Homo sapiens gamma-aminobutyric acid... 46 1e-04
BC109210-1|AAI09211.1| 632|Homo sapiens gamma-aminobutyric acid... 46 1e-04
BC096083-1|AAH96083.1| 198|Homo sapiens CHRNB4 protein protein. 46 1e-04
BC096081-1|AAH96081.1| 198|Homo sapiens CHRNB4 protein protein. 46 1e-04
AF189259-1|AAF70380.1| 632|Homo sapiens GABA-A receptor theta s... 46 1e-04
AF144648-1|AAD51172.1| 627|Homo sapiens GABA-A receptor theta p... 46 1e-04
U77731-2|AAB38273.1| 360|Homo sapiens glycine receptor alpha 2B... 46 2e-04
U30461-1|AAB52519.1| 554|Homo sapiens GABAA receptor subunit al... 46 2e-04
CR450343-1|CAG29339.1| 452|Homo sapiens GLRA2 protein. 46 2e-04
BC035055-1|AAH35055.1| 554|Homo sapiens gamma-aminobutyric acid... 46 2e-04
AY437084-1|AAR87843.1| 452|Homo sapiens glycine receptor alpha2... 46 2e-04
X52008-1|CAA36257.1| 452|Homo sapiens inhibitory glycine recept... 46 2e-04
U77731-1|AAB38272.1| 360|Homo sapiens glycine receptor alpha 2 ... 46 2e-04
BC032864-1|AAH32864.1| 452|Homo sapiens glycine receptor, alpha... 46 2e-04
AY437083-1|AAR87842.1| 452|Homo sapiens glycine receptor alpha2... 46 2e-04
AF053495-1|AAC35290.1| 452|Homo sapiens glycine receptor alpha ... 46 2e-04
U95367-1|AAC51357.1| 440|Homo sapiens GABA-A receptor pi subuni... 45 3e-04
BC109106-1|AAI09107.1| 440|Homo sapiens gamma-aminobutyric acid... 45 3e-04
BC109105-1|AAI09106.1| 440|Homo sapiens gamma-aminobutyric acid... 45 3e-04
BC074865-1|AAH74865.1| 440|Homo sapiens gamma-aminobutyric acid... 45 3e-04
BC074810-1|AAH74810.1| 440|Homo sapiens gamma-aminobutyric acid... 45 3e-04
BC033801-1|AAH33801.1| 452|Homo sapiens gamma-aminobutyric acid... 45 3e-04
AL391845-4|CAI15436.1| 452|Homo sapiens gamma-aminobutyric acid... 45 3e-04
AF016917-1|AAB70007.1| 452|Homo sapiens GABA-A receptor delta s... 45 3e-04
AF009702-1|AAC24194.1| 440|Homo sapiens GABA-A receptor pi subu... 45 3e-04
S81944-1|AAB36480.1| 453|Homo sapiens gamma-aminobutyric acid t... 44 5e-04
BC099641-1|AAH99641.1| 453|Homo sapiens gamma-aminobutyric acid... 44 5e-04
BC099640-1|AAH99640.1| 453|Homo sapiens gamma-aminobutyric acid... 44 5e-04
BC096242-1|AAH96242.1| 453|Homo sapiens gamma-aminobutyric acid... 44 5e-04
BC096241-1|AAH96241.1| 453|Homo sapiens gamma-aminobutyric acid... 44 5e-04
X52009-1|CAA36258.1| 449|Homo sapiens inhibitory glycine recept... 41 0.007
BC114947-1|AAI14948.1| 457|Homo sapiens GLRA1 protein protein. 41 0.007
BC074980-1|AAH74980.1| 449|Homo sapiens glycine receptor, alpha... 41 0.007
Z93848-1|CAI41994.1| 376|Homo sapiens glycine receptor, alpha 4... 40 0.009
AL049610-1|CAI42158.1| 376|Homo sapiens glycine receptor, alpha... 40 0.009
U93917-1|AAC39917.1| 449|Homo sapiens glycine receptor alpha 3 ... 40 0.015
BC036086-1|AAH36086.1| 464|Homo sapiens glycine receptor, alpha... 40 0.015
AF017724-1|AAC39919.1| 465|Homo sapiens glycine receptor alpha ... 40 0.015
BC114967-1|AAI14968.1| 366|Homo sapiens GLRA1 protein protein. 38 0.035
AB209359-1|BAD92596.1| 533|Homo sapiens cholinergic receptor, n... 36 0.19
BC096291-1|AAH96291.1| 556|Homo sapiens CHRNA4 protein protein. 35 0.33
BC146774-1|AAI46775.1| 1114|Homo sapiens GPR124 protein protein. 31 7.0
AY181242-1|AAO27354.1| 1331|Homo sapiens G protein-coupled recep... 31 7.0
AK074099-1|BAB84925.1| 1310|Homo sapiens FLJ00170 protein protein. 31 7.0
AK024365-1|BAB14899.1| 1148|Homo sapiens protein ( Homo sapiens ... 31 7.0
AF414442-1|AAL65133.2|22152|Homo sapiens ovarian cancer related ... 31 7.0
AF378755-1|AAL11992.1| 1331|Homo sapiens tumor endothelial marke... 31 7.0
AB040964-1|BAA96055.2| 1206|Homo sapiens KIAA1531 protein protein. 31 7.0
>AJ306454-1|CAC34819.1| 497|Homo sapiens neuronal nicotinic
acetylcholine receptor beta-4 subunit protein.
Length = 497
Score = 70.5 bits (165), Expect = 7e-12
Identities = 46/168 (27%), Positives = 77/168 (45%), Gaps = 8/168 (4%)
Frame = +2
Query: 89 AIASAAECENATSLSLMIDSLL--ATYDRESPP--DSKIVVNLTLHLRHA---NIRESES 247
A+ C A + ++D LL Y+ P S ++++ L L A ++ E E
Sbjct: 14 ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQ 73
Query: 248 TVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRAR 424
+ L+ W D RL+WN+ + G + + ++R+W PD+VL N T
Sbjct: 74 IMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNDGTYEVSVYTNLI 133
Query: 425 VSNNGSVSWIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMXNSDEMD 568
V +NGSV W+ + +++ +P D Q CT KF S + E+D
Sbjct: 134 VRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRSWTYDHTEID 181
>Y08416-1|CAA69693.1| 498|Homo sapiens nicotinic acetylcholine
receptor beta4 subunit precursor protein.
Length = 498
Score = 68.5 bits (160), Expect = 3e-11
Identities = 47/169 (27%), Positives = 78/169 (46%), Gaps = 9/169 (5%)
Frame = +2
Query: 89 AIASAAECENATSLSLMIDSLL--ATYDRESPP--DSKIVVNLTLHLRHA---NIRESES 247
A+ C A + ++D LL Y+ P S ++++ L L A ++ E E
Sbjct: 14 ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQ 73
Query: 248 TVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRA 421
+ L+ W D RL+WN+ + G + + ++R+W PD+VL N A T
Sbjct: 74 IMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNADGTYEVSVYTNL 133
Query: 422 RVSNNGSVSWIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMXNSDEMD 568
V +NGSV W+ + +++ +P D Q CT KF S + E+D
Sbjct: 134 IVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRSWTYDHTEID 182
>U62439-1|AAB40117.1| 498|Homo sapiens nicotinic acetylcholine
receptor beta4 subunit precursor protein.
Length = 498
Score = 68.5 bits (160), Expect = 3e-11
Identities = 47/169 (27%), Positives = 78/169 (46%), Gaps = 9/169 (5%)
Frame = +2
Query: 89 AIASAAECENATSLSLMIDSLL--ATYDRESPP--DSKIVVNLTLHLRHA---NIRESES 247
A+ C A + ++D LL Y+ P S ++++ L L A ++ E E
Sbjct: 14 ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQ 73
Query: 248 TVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRA 421
+ L+ W D RL+WN+ + G + + ++R+W PD+VL N A T
Sbjct: 74 IMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNADGTYEVSVYTNL 133
Query: 422 RVSNNGSVSWIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMXNSDEMD 568
V +NGSV W+ + +++ +P D Q CT KF S + E+D
Sbjct: 134 IVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRSWTYDHTEID 182
>U48861-1|AAA92123.1| 498|Homo sapiens beta 4 nicotinic
acetylcholine receptor subunit protein.
Length = 498
Score = 68.5 bits (160), Expect = 3e-11
Identities = 47/169 (27%), Positives = 78/169 (46%), Gaps = 9/169 (5%)
Frame = +2
Query: 89 AIASAAECENATSLSLMIDSLL--ATYDRESPP--DSKIVVNLTLHLRHA---NIRESES 247
A+ C A + ++D LL Y+ P S ++++ L L A ++ E E
Sbjct: 14 ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQ 73
Query: 248 TVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRA 421
+ L+ W D RL+WN+ + G + + ++R+W PD+VL N A T
Sbjct: 74 IMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNADGTYEVSVYTNL 133
Query: 422 RVSNNGSVSWIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMXNSDEMD 568
V +NGSV W+ + +++ +P D Q CT KF S + E+D
Sbjct: 134 IVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRSWTYDHTEID 182
>BC096082-1|AAH96082.1| 498|Homo sapiens cholinergic receptor,
nicotinic, beta 4 protein.
Length = 498
Score = 68.5 bits (160), Expect = 3e-11
Identities = 47/169 (27%), Positives = 78/169 (46%), Gaps = 9/169 (5%)
Frame = +2
Query: 89 AIASAAECENATSLSLMIDSLL--ATYDRESPP--DSKIVVNLTLHLRHA---NIRESES 247
A+ C A + ++D LL Y+ P S ++++ L L A ++ E E
Sbjct: 14 ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQ 73
Query: 248 TVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRA 421
+ L+ W D RL+WN+ + G + + ++R+W PD+VL N A T
Sbjct: 74 IMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNADGTYEVSVYTNL 133
Query: 422 RVSNNGSVSWIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMXNSDEMD 568
V +NGSV W+ + +++ +P D Q CT KF S + E+D
Sbjct: 134 IVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRSWTYDHTEID 182
>BC096080-1|AAH96080.1| 498|Homo sapiens cholinergic receptor,
nicotinic, beta 4 protein.
Length = 498
Score = 68.5 bits (160), Expect = 3e-11
Identities = 47/169 (27%), Positives = 78/169 (46%), Gaps = 9/169 (5%)
Frame = +2
Query: 89 AIASAAECENATSLSLMIDSLL--ATYDRESPP--DSKIVVNLTLHLRHA---NIRESES 247
A+ C A + ++D LL Y+ P S ++++ L L A ++ E E
Sbjct: 14 ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQ 73
Query: 248 TVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRA 421
+ L+ W D RL+WN+ + G + + ++R+W PD+VL N A T
Sbjct: 74 IMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNADGTYEVSVYTNL 133
Query: 422 RVSNNGSVSWIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMXNSDEMD 568
V +NGSV W+ + +++ +P D Q CT KF S + E+D
Sbjct: 134 IVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRSWTYDHTEID 182
>AF306329-1|AAL02062.1| 498|Homo sapiens neuronal nicotinic
acetylcholine receptor beta 4 subunit protein.
Length = 498
Score = 68.5 bits (160), Expect = 3e-11
Identities = 47/169 (27%), Positives = 78/169 (46%), Gaps = 9/169 (5%)
Frame = +2
Query: 89 AIASAAECENATSLSLMIDSLL--ATYDRESPP--DSKIVVNLTLHLRHA---NIRESES 247
A+ C A + ++D LL Y+ P S ++++ L L A ++ E E
Sbjct: 14 ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQ 73
Query: 248 TVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRA 421
+ L+ W D RL+WN+ + G + + ++R+W PD+VL N A T
Sbjct: 74 IMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNADGTYEVSVYTNL 133
Query: 422 RVSNNGSVSWIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMXNSDEMD 568
V +NGSV W+ + +++ +P D Q CT KF S + E+D
Sbjct: 134 IVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRSWTYDHTEID 182
>Y08417-1|CAA69694.1| 458|Homo sapiens nicotinic acetylcholine
receptor beta3 subunit precursor protein.
Length = 458
Score = 64.9 bits (151), Expect = 4e-10
Identities = 33/93 (35%), Positives = 47/93 (50%), Gaps = 2/93 (2%)
Frame = +2
Query: 269 LQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLL-NAAATTAGDYALRARVSNNGS 442
L+ W D +L WN ++G + V SE LW PD+VL NA G + V +NG+
Sbjct: 81 LKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFEGSLMTKVIVKSNGT 140
Query: 443 VSWIKRLDISTPISMQLDXWPNDMQTCTFKFGS 541
V W + +M + +P D Q C+ KFGS
Sbjct: 141 VVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGS 173
>X67513-1|CAA47851.1| 423|Homo sapiens nicotinic acetylcholine
receptor beta-3 subunit protein.
Length = 423
Score = 64.9 bits (151), Expect = 4e-10
Identities = 33/93 (35%), Positives = 47/93 (50%), Gaps = 2/93 (2%)
Frame = +2
Query: 269 LQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLL-NAAATTAGDYALRARVSNNGS 442
L+ W D +L WN ++G + V SE LW PD+VL NA G + V +NG+
Sbjct: 46 LKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFEGSLMTKVIVKSNGT 105
Query: 443 VSWIKRLDISTPISMQLDXWPNDMQTCTFKFGS 541
V W + +M + +P D Q C+ KFGS
Sbjct: 106 VVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGS 138
>U62438-1|AAB40116.1| 458|Homo sapiens nicotinic acetylcholine
receptor beta3 subunit precursor protein.
Length = 458
Score = 64.9 bits (151), Expect = 4e-10
Identities = 33/93 (35%), Positives = 47/93 (50%), Gaps = 2/93 (2%)
Frame = +2
Query: 269 LQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLL-NAAATTAGDYALRARVSNNGS 442
L+ W D +L WN ++G + V SE LW PD+VL NA G + V +NG+
Sbjct: 81 LKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFEGSLMTKVIVKSNGT 140
Query: 443 VSWIKRLDISTPISMQLDXWPNDMQTCTFKFGS 541
V W + +M + +P D Q C+ KFGS
Sbjct: 141 VVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGS 173
>BC069788-1|AAH69788.1| 458|Homo sapiens cholinergic receptor,
nicotinic, beta 3 protein.
Length = 458
Score = 64.9 bits (151), Expect = 4e-10
Identities = 33/93 (35%), Positives = 47/93 (50%), Gaps = 2/93 (2%)
Frame = +2
Query: 269 LQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLL-NAAATTAGDYALRARVSNNGS 442
L+ W D +L WN ++G + V SE LW PD+VL NA G + V +NG+
Sbjct: 81 LKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFEGSLMTKVIVKSNGT 140
Query: 443 VSWIKRLDISTPISMQLDXWPNDMQTCTFKFGS 541
V W + +M + +P D Q C+ KFGS
Sbjct: 141 VVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGS 173
>BC069703-1|AAH69703.1| 458|Homo sapiens cholinergic receptor,
nicotinic, beta 3 protein.
Length = 458
Score = 64.9 bits (151), Expect = 4e-10
Identities = 33/93 (35%), Positives = 47/93 (50%), Gaps = 2/93 (2%)
Frame = +2
Query: 269 LQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLL-NAAATTAGDYALRARVSNNGS 442
L+ W D +L WN ++G + V SE LW PD+VL NA G + V +NG+
Sbjct: 81 LKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFEGSLMTKVIVKSNGT 140
Query: 443 VSWIKRLDISTPISMQLDXWPNDMQTCTFKFGS 541
V W + +M + +P D Q C+ KFGS
Sbjct: 141 VVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGS 173
>BC069681-1|AAH69681.1| 458|Homo sapiens cholinergic receptor,
nicotinic, beta 3 protein.
Length = 458
Score = 64.9 bits (151), Expect = 4e-10
Identities = 33/93 (35%), Positives = 47/93 (50%), Gaps = 2/93 (2%)
Frame = +2
Query: 269 LQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLL-NAAATTAGDYALRARVSNNGS 442
L+ W D +L WN ++G + V SE LW PD+VL NA G + V +NG+
Sbjct: 81 LKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFEGSLMTKVIVKSNGT 140
Query: 443 VSWIKRLDISTPISMQLDXWPNDMQTCTFKFGS 541
V W + +M + +P D Q C+ KFGS
Sbjct: 141 VVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGS 173
>AF140765-1|AAD33063.1| 458|Homo sapiens neuronal acetylcholine
receptor beta-3 subunit precursor protein.
Length = 458
Score = 64.9 bits (151), Expect = 4e-10
Identities = 33/93 (35%), Positives = 47/93 (50%), Gaps = 2/93 (2%)
Frame = +2
Query: 269 LQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLL-NAAATTAGDYALRARVSNNGS 442
L+ W D +L WN ++G + V SE LW PD+VL NA G + V +NG+
Sbjct: 81 LKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFEGSLMTKVIVKSNGT 140
Query: 443 VSWIKRLDISTPISMQLDXWPNDMQTCTFKFGS 541
V W + +M + +P D Q C+ KFGS
Sbjct: 141 VVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGS 173
>X68275-1|CAA48336.1| 451|Homo sapiens nicotinic receptor beta 4
subunit protein.
Length = 451
Score = 64.5 bits (150), Expect = 5e-10
Identities = 38/129 (29%), Positives = 62/129 (48%), Gaps = 3/129 (2%)
Frame = +2
Query: 191 IVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 364
I + L L L ++ E + + L+ W D RL+WN+ + G + + ++R+W P
Sbjct: 7 ISIKLQLSLAQLISVNERDEIMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLP 66
Query: 365 DVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDXWPNDMQTCTFKFGS 541
D+VL N A T V +NGSV W+ + +++ +P D Q CT KF S
Sbjct: 67 DIVLYNNADGTYEVSVYTNLIVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRS 126
Query: 542 RMXNSDEMD 568
+ E+D
Sbjct: 127 WTYDHTEID 135
>Y08419-1|CAA69696.1| 468|Homo sapiens nicotinic acetylcholine
receptor alpha5 subunit precursor protein.
Length = 468
Score = 64.1 bits (149), Expect = 6e-10
Identities = 37/150 (24%), Positives = 70/150 (46%), Gaps = 6/150 (4%)
Frame = +2
Query: 137 MIDSLLATYDRESPP----DSKIVVNLTLHLRH-ANIRESESTVRILADLQMNWIDKRLS 301
++ L Y+R P + KI + L + ++ E + L+ WID +L
Sbjct: 50 LLKDLFQDYERWVRPVEHLNDKIKIKFGLAISQLVDVDEKNQLMTTNVWLKQEWIDVKLR 109
Query: 302 WNAGEWG-CSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVSWIKRLDISTP 478
WN ++G V S+ +W PD+VL + A + + + NG+V+W + +
Sbjct: 110 WNPDDYGGIKVIRVPSDSVWTPDIVLFDNADGRFEGTSTKTVIRYNGTVTWTPPANYKSS 169
Query: 479 ISMQLDXWPNDMQTCTFKFGSRMXNSDEMD 568
++ + +P D+Q C+ KFGS + ++D
Sbjct: 170 CTIDVTFFPFDLQNCSMKFGSWTYDGSQVD 199
>X14830-1|CAA32939.1| 501|Homo sapiens protein ( Human mRNA for
muscle acetylcholine receptor beta-subunit. ).
Length = 501
Score = 64.1 bits (149), Expect = 6e-10
Identities = 47/137 (34%), Positives = 69/137 (50%), Gaps = 4/137 (2%)
Frame = +2
Query: 167 RESPPDSKIVVNLTL-HLRHANIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLV 340
RE ++ V L L L N ++ E + ++ DL+ W D RLSW+ E G + +
Sbjct: 46 REVGDRVRVSVGLILAQLISLNEKDEEMSTKVYLDLE--WTDYRLSWDPAEHDGIDSLRI 103
Query: 341 SSERLWRPDVVLLNAAATTAGDYAL--RARVSNNGSVSWIKRLDISTPISMQLDXWPNDM 514
++E +W PDVVLLN D AL VS++GSV W + S+Q+ +P D
Sbjct: 104 TAESVWLPDVVLLNNNDGNF-DVALDISVVVSSDGSVRWQPPGIYRSSCSIQVTYFPFDW 162
Query: 515 QTCTFKFGSRMXNSDEM 565
Q CT F S +S E+
Sbjct: 163 QNCTMVFSSYSYDSSEV 179
>U62434-1|AAB40112.1| 468|Homo sapiens nicotinic acetylcholine
receptor alpha5 subunit precursor protein.
Length = 468
Score = 64.1 bits (149), Expect = 6e-10
Identities = 37/150 (24%), Positives = 70/150 (46%), Gaps = 6/150 (4%)
Frame = +2
Query: 137 MIDSLLATYDRESPP----DSKIVVNLTLHLRH-ANIRESESTVRILADLQMNWIDKRLS 301
++ L Y+R P + KI + L + ++ E + L+ WID +L
Sbjct: 50 LLKDLFQDYERWVRPVEHLNDKIKIKFGLAISQLVDVDEKNQLMTTNVWLKQEWIDVKLR 109
Query: 302 WNAGEWG-CSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVSWIKRLDISTP 478
WN ++G V S+ +W PD+VL + A + + + NG+V+W + +
Sbjct: 110 WNPDDYGGIKVIRVPSDSVWTPDIVLFDNADGRFEGTSTKTVIRYNGTVTWTPPANYKSS 169
Query: 479 ISMQLDXWPNDMQTCTFKFGSRMXNSDEMD 568
++ + +P D+Q C+ KFGS + ++D
Sbjct: 170 CTIDVTFFPFDLQNCSMKFGSWTYDGSQVD 199
>BC033639-1|AAH33639.1| 468|Homo sapiens cholinergic receptor,
nicotinic, alpha 5 protein.
Length = 468
Score = 64.1 bits (149), Expect = 6e-10
Identities = 37/150 (24%), Positives = 70/150 (46%), Gaps = 6/150 (4%)
Frame = +2
Query: 137 MIDSLLATYDRESPP----DSKIVVNLTLHLRH-ANIRESESTVRILADLQMNWIDKRLS 301
++ L Y+R P + KI + L + ++ E + L+ WID +L
Sbjct: 50 LLKDLFQDYERWVRPVEHLNDKIKIKFGLAISQLVDVDEKNQLMTTNVWLKQEWIDVKLR 109
Query: 302 WNAGEWG-CSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVSWIKRLDISTP 478
WN ++G V S+ +W PD+VL + A + + + NG+V+W + +
Sbjct: 110 WNPDDYGGIKVIRVPSDSVWTPDIVLFDNADGRFEGTSTKTVIRYNGTVTWTPPANYKSS 169
Query: 479 ISMQLDXWPNDMQTCTFKFGSRMXNSDEMD 568
++ + +P D+Q C+ KFGS + ++D
Sbjct: 170 CTIDVTFFPFDLQNCSMKFGSWTYDGSQVD 199
>BC011371-1|AAH11371.1| 501|Homo sapiens cholinergic receptor,
nicotinic, beta 1 (muscle) protein.
Length = 501
Score = 64.1 bits (149), Expect = 6e-10
Identities = 47/137 (34%), Positives = 69/137 (50%), Gaps = 4/137 (2%)
Frame = +2
Query: 167 RESPPDSKIVVNLTL-HLRHANIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLV 340
RE ++ V L L L N ++ E + ++ DL+ W D RLSW+ E G + +
Sbjct: 46 REVGDRVRVSVGLILAQLISLNEKDEEMSTKVYLDLE--WTDYRLSWDPAEHDGIDSLRI 103
Query: 341 SSERLWRPDVVLLNAAATTAGDYAL--RARVSNNGSVSWIKRLDISTPISMQLDXWPNDM 514
++E +W PDVVLLN D AL VS++GSV W + S+Q+ +P D
Sbjct: 104 TAESVWLPDVVLLNNNDGNF-DVALDISVVVSSDGSVRWQPPGIYRSSCSIQVTYFPFDW 162
Query: 515 QTCTFKFGSRMXNSDEM 565
Q CT F S +S E+
Sbjct: 163 QNCTMVFSSYSYDSSEV 179
>AJ306481-1|CAC34820.1| 468|Homo sapiens neuronal nicotinic
acetylcholine receptor alpha-5subunit protein.
Length = 468
Score = 64.1 bits (149), Expect = 6e-10
Identities = 37/150 (24%), Positives = 70/150 (46%), Gaps = 6/150 (4%)
Frame = +2
Query: 137 MIDSLLATYDRESPP----DSKIVVNLTLHLRH-ANIRESESTVRILADLQMNWIDKRLS 301
++ L Y+R P + KI + L + ++ E + L+ WID +L
Sbjct: 50 LLKDLFQDYERWVRPVEHLNDKIKIKFGLAISQLVDVDEKNQLMTTNVWLKQEWIDVKLR 109
Query: 302 WNAGEWG-CSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVSWIKRLDISTP 478
WN ++G V S+ +W PD+VL + A + + + NG+V+W + +
Sbjct: 110 WNPDDYGGIKVIRVPSDSVWTPDIVLFDNADGRFEGTSTKTVIRYNGTVTWTPPANYKSS 169
Query: 479 ISMQLDXWPNDMQTCTFKFGSRMXNSDEMD 568
++ + +P D+Q C+ KFGS + ++D
Sbjct: 170 CTIDVTFFPFDLQNCSMKFGSWTYDGSQVD 199
>Y16281-1|CAA76154.1| 529|Homo sapiens nicotinic acetylcholine
receptor alpha2 subunit precursor protein.
Length = 529
Score = 63.7 bits (148), Expect = 8e-10
Identities = 34/102 (33%), Positives = 53/102 (51%), Gaps = 2/102 (1%)
Frame = +2
Query: 269 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAA-ATTAGDYALRARVSNNGS 442
L+ W D +L WN ++G T L V SE +W PD+VL N A A + +A + + G+
Sbjct: 111 LKQEWSDYKLRWNPADFGNITSLRVPSEMIWIPDIVLYNNADGEFAVTHMTKAHLFSTGT 170
Query: 443 VSWIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMXNSDEMD 568
V W+ + S+ + +P D Q C KFGS + ++D
Sbjct: 171 VHWVPPAIYKSSCSIDVTFFPFDQQNCKMKFGSWTYDKAKID 212
>U62431-1|AAB40109.1| 529|Homo sapiens nicotinic acetylcholine
receptor alpha2 subunit precursor protein.
Length = 529
Score = 63.7 bits (148), Expect = 8e-10
Identities = 34/102 (33%), Positives = 53/102 (51%), Gaps = 2/102 (1%)
Frame = +2
Query: 269 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAA-ATTAGDYALRARVSNNGS 442
L+ W D +L WN ++G T L V SE +W PD+VL N A A + +A + + G+
Sbjct: 111 LKQEWSDYKLRWNPADFGNITSLRVPSEMIWIPDIVLYNNADGEFAVTHMTKAHLFSTGT 170
Query: 443 VSWIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMXNSDEMD 568
V W+ + S+ + +P D Q C KFGS + ++D
Sbjct: 171 VHWVPPAIYKSSCSIDVTFFPFDQQNCKMKFGSWTYDKAKID 212
>Y16282-1|CAA76155.1| 494|Homo sapiens nicotinic acetylcholine
receptor alpha6 subunit precursor protein.
Length = 494
Score = 63.3 bits (147), Expect = 1e-09
Identities = 42/163 (25%), Positives = 75/163 (46%), Gaps = 10/163 (6%)
Frame = +2
Query: 110 CENATSLSLMIDSLLATYDRESPPDSKIVVNLTLHL-----RHANIRESESTVRILADLQ 274
C + + L + Y++ P + +T+H + AN+ E + L+
Sbjct: 28 CVGCATEERLFHKLFSHYNQFIRPVENVSDPVTVHFEVAITQLANVDEVNQIMETNLWLR 87
Query: 275 MNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNG 439
W D +L W+ E+ G T V ++++W+PD+VL N A GD+ + +A + NG
Sbjct: 88 HIWNDYKLRWDPMEYDGIETLRVPADKIWKPDIVLYNNAV---GDFQVEGKTKALLKYNG 144
Query: 440 SVSWIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMXNSDEMD 568
++W + M + +P D Q C+ KFGS + E+D
Sbjct: 145 MITWTPPAIFKSSCPMDITFFPFDHQNCSLKFGSWTYDKAEID 187
>Y08418-1|CAA69695.1| 503|Homo sapiens nicotinic acetylcholine
receptor alpha3 subunit precursor protein.
Length = 503
Score = 63.3 bits (147), Expect = 1e-09
Identities = 31/102 (30%), Positives = 54/102 (52%), Gaps = 2/102 (1%)
Frame = +2
Query: 269 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 442
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 85 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 144
Query: 443 VSWIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMXNSDEMD 568
V+WI + + + +P D Q CT KFGS + ++D
Sbjct: 145 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKID 186
>X53559-1|CAA37625.1| 474|Homo sapiens neuronal nicotinic
acetylcholine receptor alpha-3merase protein.
Length = 474
Score = 63.3 bits (147), Expect = 1e-09
Identities = 31/102 (30%), Positives = 54/102 (52%), Gaps = 2/102 (1%)
Frame = +2
Query: 269 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 442
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 56 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 115
Query: 443 VSWIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMXNSDEMD 568
V+WI + + + +P D Q CT KFGS + ++D
Sbjct: 116 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKID 157
>U62435-1|AAB40113.1| 494|Homo sapiens nicotinic acetylcholine
receptor alpha6 subunit precursor protein.
Length = 494
Score = 63.3 bits (147), Expect = 1e-09
Identities = 42/163 (25%), Positives = 75/163 (46%), Gaps = 10/163 (6%)
Frame = +2
Query: 110 CENATSLSLMIDSLLATYDRESPPDSKIVVNLTLHL-----RHANIRESESTVRILADLQ 274
C + + L + Y++ P + +T+H + AN+ E + L+
Sbjct: 28 CVGCATEERLFHKLFSHYNQFIRPVENVSDPVTVHFEVAITQLANVDEVNQIMETNLWLR 87
Query: 275 MNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNG 439
W D +L W+ E+ G T V ++++W+PD+VL N A GD+ + +A + NG
Sbjct: 88 HIWNDYKLRWDPMEYDGIETLRVPADKIWKPDIVLYNNAV---GDFQVEGKTKALLKYNG 144
Query: 440 SVSWIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMXNSDEMD 568
++W + M + +P D Q C+ KFGS + E+D
Sbjct: 145 MITWTPPAIFKSSCPMDITFFPFDHQNCSLKFGSWTYDKAEID 187
>U62432-1|AAB40110.1| 504|Homo sapiens nicotinic acetylcholine
receptor alpha3 subunit precursor protein.
Length = 504
Score = 63.3 bits (147), Expect = 1e-09
Identities = 31/102 (30%), Positives = 54/102 (52%), Gaps = 2/102 (1%)
Frame = +2
Query: 269 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 442
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 86 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 145
Query: 443 VSWIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMXNSDEMD 568
V+WI + + + +P D Q CT KFGS + ++D
Sbjct: 146 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKID 187
>M37981-1|AAA59942.1| 503|Homo sapiens neuronal nicotinic
acetylcholine receptor protein.
Length = 503
Score = 63.3 bits (147), Expect = 1e-09
Identities = 31/102 (30%), Positives = 54/102 (52%), Gaps = 2/102 (1%)
Frame = +2
Query: 269 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 442
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 85 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 144
Query: 443 VSWIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMXNSDEMD 568
V+WI + + + +P D Q CT KFGS + ++D
Sbjct: 145 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKID 186
>BT006897-1|AAP35543.1| 505|Homo sapiens cholinergic receptor,
nicotinic, alpha polypeptide 3 protein.
Length = 505
Score = 63.3 bits (147), Expect = 1e-09
Identities = 31/102 (30%), Positives = 54/102 (52%), Gaps = 2/102 (1%)
Frame = +2
Query: 269 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 442
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 87 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 146
Query: 443 VSWIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMXNSDEMD 568
V+WI + + + +P D Q CT KFGS + ++D
Sbjct: 147 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKID 188
>BT006646-1|AAP35292.1| 489|Homo sapiens cholinergic receptor,
nicotinic, alpha polypeptide 3 protein.
Length = 489
Score = 63.3 bits (147), Expect = 1e-09
Identities = 31/102 (30%), Positives = 54/102 (52%), Gaps = 2/102 (1%)
Frame = +2
Query: 269 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 442
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 87 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 146
Query: 443 VSWIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMXNSDEMD 568
V+WI + + + +P D Q CT KFGS + ++D
Sbjct: 147 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKID 188
>BC098443-1|AAH98443.1| 504|Homo sapiens cholinergic receptor,
nicotinic, alpha 3 protein.
Length = 504
Score = 63.3 bits (147), Expect = 1e-09
Identities = 31/102 (30%), Positives = 54/102 (52%), Gaps = 2/102 (1%)
Frame = +2
Query: 269 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 442
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 86 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 145
Query: 443 VSWIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMXNSDEMD 568
V+WI + + + +P D Q CT KFGS + ++D
Sbjct: 146 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKID 187
>BC014456-1|AAH14456.1| 494|Homo sapiens cholinergic receptor,
nicotinic, alpha 6 protein.
Length = 494
Score = 63.3 bits (147), Expect = 1e-09
Identities = 42/163 (25%), Positives = 75/163 (46%), Gaps = 10/163 (6%)
Frame = +2
Query: 110 CENATSLSLMIDSLLATYDRESPPDSKIVVNLTLHL-----RHANIRESESTVRILADLQ 274
C + + L + Y++ P + +T+H + AN+ E + L+
Sbjct: 28 CVGCATEERLFHKLFSHYNQFIRPVENVSDPVTVHFEVAITQLANVDEVNQIMETNLWLR 87
Query: 275 MNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNG 439
W D +L W+ E+ G T V ++++W+PD+VL N A GD+ + +A + NG
Sbjct: 88 HIWNDYKLRWDPMEYDGIETLRVPADKIWKPDIVLYNNAV---GDFQVEGKTKALLKYNG 144
Query: 440 SVSWIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMXNSDEMD 568
++W + M + +P D Q C+ KFGS + E+D
Sbjct: 145 MITWTPPAIFKSSCPMDITFFPFDHQNCSLKFGSWTYDKAEID 187
>BC006114-1|AAH06114.1| 489|Homo sapiens CHRNA3 protein protein.
Length = 489
Score = 63.3 bits (147), Expect = 1e-09
Identities = 31/102 (30%), Positives = 54/102 (52%), Gaps = 2/102 (1%)
Frame = +2
Query: 269 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 442
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 87 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 146
Query: 443 VSWIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMXNSDEMD 568
V+WI + + + +P D Q CT KFGS + ++D
Sbjct: 147 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKID 188
>BC002996-1|AAH02996.1| 505|Homo sapiens cholinergic receptor,
nicotinic, alpha 3 protein.
Length = 505
Score = 63.3 bits (147), Expect = 1e-09
Identities = 31/102 (30%), Positives = 54/102 (52%), Gaps = 2/102 (1%)
Frame = +2
Query: 269 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 442
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 87 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 146
Query: 443 VSWIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMXNSDEMD 568
V+WI + + + +P D Q CT KFGS + ++D
Sbjct: 147 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKID 188
>BC001642-1|AAH01642.1| 505|Homo sapiens cholinergic receptor,
nicotinic, alpha 3 protein.
Length = 505
Score = 63.3 bits (147), Expect = 1e-09
Identities = 31/102 (30%), Positives = 54/102 (52%), Gaps = 2/102 (1%)
Frame = +2
Query: 269 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 442
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 87 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 146
Query: 443 VSWIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMXNSDEMD 568
V+WI + + + +P D Q CT KFGS + ++D
Sbjct: 147 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKID 188
>BC000513-1|AAH00513.1| 505|Homo sapiens cholinergic receptor,
nicotinic, alpha 3 protein.
Length = 505
Score = 63.3 bits (147), Expect = 1e-09
Identities = 31/102 (30%), Positives = 54/102 (52%), Gaps = 2/102 (1%)
Frame = +2
Query: 269 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 442
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 87 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 146
Query: 443 VSWIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMXNSDEMD 568
V+WI + + + +P D Q CT KFGS + ++D
Sbjct: 147 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKID 188
>AJ007783-1|CAA07682.1| 504|Homo sapiens nicotinic acetylcholine
receptor alpha-3 subunit protein.
Length = 504
Score = 63.3 bits (147), Expect = 1e-09
Identities = 31/102 (30%), Positives = 54/102 (52%), Gaps = 2/102 (1%)
Frame = +2
Query: 269 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 442
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 86 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 145
Query: 443 VSWIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMXNSDEMD 568
V+WI + + + +P D Q CT KFGS + ++D
Sbjct: 146 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKID 187
>AF385584-1|AAK68110.1| 489|Homo sapiens nicotinic cholinergic
receptor alpha 3 protein.
Length = 489
Score = 63.3 bits (147), Expect = 1e-09
Identities = 31/102 (30%), Positives = 54/102 (52%), Gaps = 2/102 (1%)
Frame = +2
Query: 269 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 442
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 81 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 140
Query: 443 VSWIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMXNSDEMD 568
V+WI + + + +P D Q CT KFGS + ++D
Sbjct: 141 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKID 182
>AB079251-1|BAC06855.1| 494|Homo sapiens Nicotinic acetylcholine
receptor alpha 6 protein.
Length = 494
Score = 63.3 bits (147), Expect = 1e-09
Identities = 42/163 (25%), Positives = 75/163 (46%), Gaps = 10/163 (6%)
Frame = +2
Query: 110 CENATSLSLMIDSLLATYDRESPPDSKIVVNLTLHL-----RHANIRESESTVRILADLQ 274
C + + L + Y++ P + +T+H + AN+ E + L+
Sbjct: 28 CVGCATEERLFHKLFSHYNQFIRPVENVSDPVTVHFEVAITQLANVDEVNQIMETNLWLR 87
Query: 275 MNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNG 439
W D +L W+ E+ G T V ++++W+PD+VL N A GD+ + +A + NG
Sbjct: 88 HIWNDYKLRWDPMEYDGIETLRVPADKIWKPDIVLYNNAV---GDFQVEGKTKALLKYNG 144
Query: 440 SVSWIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMXNSDEMD 568
++W + M + +P D Q C+ KFGS + E+D
Sbjct: 145 MITWTPPAIFKSSCPMDITFFPFDHQNCSLKFGSWTYDKAEID 187
>M83712-1|AAA58357.1| 468|Homo sapiens nicotinic receptor alpha 5
subunit protein.
Length = 468
Score = 62.9 bits (146), Expect = 1e-09
Identities = 37/150 (24%), Positives = 69/150 (46%), Gaps = 6/150 (4%)
Frame = +2
Query: 137 MIDSLLATYDRESPP----DSKIVVNLTLHLRH-ANIRESESTVRILADLQMNWIDKRLS 301
++ L Y+R P + KI + L + ++ E + L+ WID +L
Sbjct: 50 LLKDLFQDYERWVRPVEHLNDKIKIKFGLAISQLVDVDEKNQLMTTNVWLKQEWIDVKLR 109
Query: 302 WNAGEWG-CSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVSWIKRLDISTP 478
WN ++G V S+ W PD+VL + A + + + NG+V+W + +
Sbjct: 110 WNPDDYGGIKVIRVPSDSSWTPDIVLFDNADGRFEGTSTKTVIRYNGTVTWTPPANYKSS 169
Query: 479 ISMQLDXWPNDMQTCTFKFGSRMXNSDEMD 568
++ + +P D+Q C+ KFGS + ++D
Sbjct: 170 CTIDVTFFPFDLQNCSMKFGSWTYDGSQVD 199
>BC023553-1|AAH23553.1| 501|Homo sapiens cholinergic receptor,
nicotinic, beta 1 (muscle) protein.
Length = 501
Score = 62.9 bits (146), Expect = 1e-09
Identities = 45/139 (32%), Positives = 70/139 (50%), Gaps = 6/139 (4%)
Frame = +2
Query: 167 RESPPDSKIVVNLTL-HLRHANIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLV 340
RE ++ V L L L N ++ E + ++ DL+ W D RLSW+ E G + +
Sbjct: 46 REVGDRVRVSVGLILAQLISLNEKDEEMSTKVYLDLE--WTDYRLSWDPAEHDGIDSLRI 103
Query: 341 SSERLWRPDVVLLNAAATTAGDY----ALRARVSNNGSVSWIKRLDISTPISMQLDXWPN 508
++E +W PDVVLLN G++ + VS++GSV W + S+Q+ +P
Sbjct: 104 TAESVWLPDVVLLN---NNDGNFYVALDISVVVSSDGSVRWQPPGIYRSSCSIQVTYFPF 160
Query: 509 DMQTCTFKFGSRMXNSDEM 565
D Q CT F S +S E+
Sbjct: 161 DWQNCTMVFSSYSYDSSEV 179
>X66403-1|CAA47030.1| 493|Homo sapiens acetylcholine receptor
epsilon subunit CHRNE protein.
Length = 493
Score = 62.5 bits (145), Expect = 2e-09
Identities = 36/134 (26%), Positives = 70/134 (52%), Gaps = 3/134 (2%)
Frame = +2
Query: 179 PDSKIVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEWG-CSTWLVSSER 352
P+ + ++L + L + ++ E E T+ + ++W D RL+++ ++G T V SE
Sbjct: 45 PEDTVTISLKVTLTNLISLNEKEETLTTSVWIGIDWQDYRLNYSKDDFGGIETLRVPSEL 104
Query: 353 LWRPDVVLLNAAATTAG-DYALRARVSNNGSVSWIKRLDISTPISMQLDXWPNDMQTCTF 529
+W P++VL N G Y V GSV+W+ + ++++ +P D Q C+
Sbjct: 105 VWLPEIVLENNIDGQFGVAYDANVLVYEGGSVTWLPPAIYRSVCAVEVTYFPFDWQNCSL 164
Query: 530 KFGSRMXNSDEMDF 571
F S+ N++E++F
Sbjct: 165 IFRSQTYNAEEVEF 178
>AF105999-1|AAD24503.1| 493|Homo sapiens acetylcholine receptor
epsilon subunit protein.
Length = 493
Score = 62.5 bits (145), Expect = 2e-09
Identities = 36/134 (26%), Positives = 70/134 (52%), Gaps = 3/134 (2%)
Frame = +2
Query: 179 PDSKIVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEWG-CSTWLVSSER 352
P+ + ++L + L + ++ E E T+ + ++W D RL+++ ++G T V SE
Sbjct: 45 PEDTVTISLKVTLTNLISLNEKEETLTTSVWIGIDWQDYRLNYSKDDFGGIETLRVPSEL 104
Query: 353 LWRPDVVLLNAAATTAG-DYALRARVSNNGSVSWIKRLDISTPISMQLDXWPNDMQTCTF 529
+W P++VL N G Y V GSV+W+ + ++++ +P D Q C+
Sbjct: 105 VWLPEIVLENNIDGQFGVAYDANVLVYEGGSVTWLPPAIYRSVCAVEVTYFPFDWQNCSL 164
Query: 530 KFGSRMXNSDEMDF 571
F S+ N++E++F
Sbjct: 165 IFRSQTYNAEEVEF 178
>Y08421-1|CAA69698.1| 627|Homo sapiens nicotinic acetylcholine
receptor alpha4 subunit precursor protein.
Length = 627
Score = 60.9 bits (141), Expect = 6e-09
Identities = 42/154 (27%), Positives = 78/154 (50%), Gaps = 10/154 (6%)
Frame = +2
Query: 137 MIDSLLATYDRESPPDSKI--VVNLTLHLRHANIRESESTVRILAD---LQMNWIDKRLS 301
++ L + Y++ S P + I VV + L A + + + +++ ++ W D +L
Sbjct: 40 LLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLR 99
Query: 302 WNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNGSVSWIKRLD 466
W+ ++ T + + SE +WRPD+VL N A GD+A+ +A + ++G V W
Sbjct: 100 WDPADYENVTSIRIPSELIWRPDIVLYNNAD---GDFAVTHLTKAHLFHDGRVQWTPPAI 156
Query: 467 ISTPISMQLDXWPNDMQTCTFKFGSRMXNSDEMD 568
+ S+ + +P D Q CT KFGS + ++D
Sbjct: 157 YKSSCSIDVTFFPFDQQNCTMKFGSWTYDKAKID 190
>X89741-1|CAA61893.1| 627|Homo sapiens neuronal acetylcholine
receptor alpha-4 subunit protein.
Length = 627
Score = 60.9 bits (141), Expect = 6e-09
Identities = 42/154 (27%), Positives = 78/154 (50%), Gaps = 10/154 (6%)
Frame = +2
Query: 137 MIDSLLATYDRESPPDSKI--VVNLTLHLRHANIRESESTVRILAD---LQMNWIDKRLS 301
++ L + Y++ S P + I VV + L A + + + +++ ++ W D +L
Sbjct: 40 LLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLR 99
Query: 302 WNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNGSVSWIKRLD 466
W+ ++ T + + SE +WRPD+VL N A GD+A+ +A + ++G V W
Sbjct: 100 WDPADYENVTSIRIPSELIWRPDIVLYNNAD---GDFAVTHLTKAHLFHDGRVQWTPPAI 156
Query: 467 ISTPISMQLDXWPNDMQTCTFKFGSRMXNSDEMD 568
+ S+ + +P D Q CT KFGS + ++D
Sbjct: 157 YKSSCSIDVTFFPFDQQNCTMKFGSWTYDKAKID 190
>X87629-1|CAA60959.1| 602|Homo sapiens nicotinic acetylcholine
receptor protein.
Length = 602
Score = 60.9 bits (141), Expect = 6e-09
Identities = 42/154 (27%), Positives = 78/154 (50%), Gaps = 10/154 (6%)
Frame = +2
Query: 137 MIDSLLATYDRESPPDSKI--VVNLTLHLRHANIRESESTVRILAD---LQMNWIDKRLS 301
++ L + Y++ S P + I VV + L A + + + +++ ++ W D +L
Sbjct: 15 LLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLR 74
Query: 302 WNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNGSVSWIKRLD 466
W+ ++ T + + SE +WRPD+VL N A GD+A+ +A + ++G V W
Sbjct: 75 WDPADYENVTSIRIPSELIWRPDIVLYNNAD---GDFAVTHLTKAHLFHDGRVQWTPPAI 131
Query: 467 ISTPISMQLDXWPNDMQTCTFKFGSRMXNSDEMD 568
+ S+ + +P D Q CT KFGS + ++D
Sbjct: 132 YKSSCSIDVTFFPFDQQNCTMKFGSWTYDKAKID 165
>U62433-1|AAB40111.1| 627|Homo sapiens nicotinic acetylcholine
receptor alpha4 subunit precursor protein.
Length = 627
Score = 60.9 bits (141), Expect = 6e-09
Identities = 42/154 (27%), Positives = 78/154 (50%), Gaps = 10/154 (6%)
Frame = +2
Query: 137 MIDSLLATYDRESPPDSKI--VVNLTLHLRHANIRESESTVRILAD---LQMNWIDKRLS 301
++ L + Y++ S P + I VV + L A + + + +++ ++ W D +L
Sbjct: 40 LLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLR 99
Query: 302 WNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNGSVSWIKRLD 466
W+ ++ T + + SE +WRPD+VL N A GD+A+ +A + ++G V W
Sbjct: 100 WDPADYENVTSIRIPSELIWRPDIVLYNNAD---GDFAVTHLTKAHLFHDGRVQWTPPAI 156
Query: 467 ISTPISMQLDXWPNDMQTCTFKFGSRMXNSDEMD 568
+ S+ + +P D Q CT KFGS + ++D
Sbjct: 157 YKSSCSIDVTFFPFDQQNCTMKFGSWTYDKAKID 190
>M86383-1|AAC84176.1| 502|Homo sapiens nicotinic acetylcholine
receptor alpha 3 subunit precursor protein.
Length = 502
Score = 60.9 bits (141), Expect = 6e-09
Identities = 32/105 (30%), Positives = 56/105 (53%), Gaps = 5/105 (4%)
Frame = +2
Query: 269 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYAL----RARVSN 433
L+ W D +L WN +G + ++ V ++++W+PD+VL N A GD+ + +A +
Sbjct: 84 LKQIWNDYKLKWNPSGYGGAEFMRVPAQKIWKPDIVLYNNAV---GDFQVTTKTKALLKY 140
Query: 434 NGSVSWIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMXNSDEMD 568
G V+WI + + + +P D Q CT KFGS + ++D
Sbjct: 141 TGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKID 185
>L35901-1|AAA64743.1| 627|Homo sapiens nicotinic acetylcholine
receptor alpha 4 subunit protein.
Length = 627
Score = 60.9 bits (141), Expect = 6e-09
Identities = 42/154 (27%), Positives = 78/154 (50%), Gaps = 10/154 (6%)
Frame = +2
Query: 137 MIDSLLATYDRESPPDSKI--VVNLTLHLRHANIRESESTVRILAD---LQMNWIDKRLS 301
++ L + Y++ S P + I VV + L A + + + +++ ++ W D +L
Sbjct: 40 LLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLR 99
Query: 302 WNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNGSVSWIKRLD 466
W+ ++ T + + SE +WRPD+VL N A GD+A+ +A + ++G V W
Sbjct: 100 WDPADYENVTSIRIPSELIWRPDIVLYNNAD---GDFAVTHLTKAHLFHDGRVQWTPPAI 156
Query: 467 ISTPISMQLDXWPNDMQTCTFKFGSRMXNSDEMD 568
+ S+ + +P D Q CT KFGS + ++D
Sbjct: 157 YKSSCSIDVTFFPFDQQNCTMKFGSWTYDKAKID 190
>DQ093071-1|AAY88737.1| 627|Homo sapiens cholinergic receptor,
nicotinic, alpha polypeptide 4 protein.
Length = 627
Score = 60.9 bits (141), Expect = 6e-09
Identities = 42/154 (27%), Positives = 78/154 (50%), Gaps = 10/154 (6%)
Frame = +2
Query: 137 MIDSLLATYDRESPPDSKI--VVNLTLHLRHANIRESESTVRILAD---LQMNWIDKRLS 301
++ L + Y++ S P + I VV + L A + + + +++ ++ W D +L
Sbjct: 40 LLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLR 99
Query: 302 WNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNGSVSWIKRLD 466
W+ ++ T + + SE +WRPD+VL N A GD+A+ +A + ++G V W
Sbjct: 100 WDPADYENVTSIRIPSELIWRPDIVLYNNAD---GDFAVTHLTKAHLFHDGRVQWTPPAI 156
Query: 467 ISTPISMQLDXWPNDMQTCTFKFGSRMXNSDEMD 568
+ S+ + +P D Q CT KFGS + ++D
Sbjct: 157 YKSSCSIDVTFFPFDQQNCTMKFGSWTYDKAKID 190
>BC096290-1|AAH96290.1| 627|Homo sapiens cholinergic receptor,
nicotinic, alpha 4 protein.
Length = 627
Score = 60.9 bits (141), Expect = 6e-09
Identities = 42/154 (27%), Positives = 78/154 (50%), Gaps = 10/154 (6%)
Frame = +2
Query: 137 MIDSLLATYDRESPPDSKI--VVNLTLHLRHANIRESESTVRILAD---LQMNWIDKRLS 301
++ L + Y++ S P + I VV + L A + + + +++ ++ W D +L
Sbjct: 40 LLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLR 99
Query: 302 WNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNGSVSWIKRLD 466
W+ ++ T + + SE +WRPD+VL N A GD+A+ +A + ++G V W
Sbjct: 100 WDPADYENVTSIRIPSELIWRPDIVLYNNAD---GDFAVTHLTKAHLFHDGRVQWTPPAI 156
Query: 467 ISTPISMQLDXWPNDMQTCTFKFGSRMXNSDEMD 568
+ S+ + +P D Q CT KFGS + ++D
Sbjct: 157 YKSSCSIDVTFFPFDQQNCTMKFGSWTYDKAKID 190
>BC113575-1|AAI13576.1| 479|Homo sapiens cholinergic receptor,
nicotinic, alpha 9 protein.
Length = 479
Score = 60.1 bits (139), Expect = 1e-08
Identities = 44/180 (24%), Positives = 81/180 (45%), Gaps = 10/180 (5%)
Frame = +2
Query: 59 YSCYQFLLTCAIAS---AAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRH 223
+SC F AS AAE + + + L Y P D+ V+N+TL +
Sbjct: 5 HSCISFCWIYFAASRLRAAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQITL 64
Query: 224 ANIRESESTVRILAD---LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAA 391
+ I++ + +IL ++ W D L+W+ ++ G + + S+ +WRPD+VL N A
Sbjct: 65 SQIKDMDERNQILTAYLWIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKAD 124
Query: 392 TTAGD-YALRARVSNNGSVSWIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMXNSDEMD 568
+ + + +G ++W + + + +P D Q C FGS N +++D
Sbjct: 125 DESSEPVNTNVVLRYDGLITWDAPAITKSSCVVDVTYFPFDNQQCNLTFGSWTYNGNQVD 184
>BC113549-1|AAI13550.1| 479|Homo sapiens cholinergic receptor,
nicotinic, alpha 9 protein.
Length = 479
Score = 60.1 bits (139), Expect = 1e-08
Identities = 44/180 (24%), Positives = 81/180 (45%), Gaps = 10/180 (5%)
Frame = +2
Query: 59 YSCYQFLLTCAIAS---AAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRH 223
+SC F AS AAE + + + L Y P D+ V+N+TL +
Sbjct: 5 HSCISFCWIYFAASRLRAAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQITL 64
Query: 224 ANIRESESTVRILAD---LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAA 391
+ I++ + +IL ++ W D L+W+ ++ G + + S+ +WRPD+VL N A
Sbjct: 65 SQIKDMDERNQILTAYLWIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKAD 124
Query: 392 TTAGD-YALRARVSNNGSVSWIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMXNSDEMD 568
+ + + +G ++W + + + +P D Q C FGS N +++D
Sbjct: 125 DESSEPVNTNVVLRYDGLITWDAPAITKSSCVVDVTYFPFDNQQCNLTFGSWTYNGNQVD 184
>AY123244-1|AAM74523.1| 479|Homo sapiens nicotinic acetylcholine
receptor subunit alpha 9 protein.
Length = 479
Score = 60.1 bits (139), Expect = 1e-08
Identities = 44/180 (24%), Positives = 81/180 (45%), Gaps = 10/180 (5%)
Frame = +2
Query: 59 YSCYQFLLTCAIAS---AAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRH 223
+SC F AS AAE + + + L Y P D+ V+N+TL +
Sbjct: 5 HSCISFCWIYFAASRLRAAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQITL 64
Query: 224 ANIRESESTVRILAD---LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAA 391
+ I++ + +IL ++ W D L+W+ ++ G + + S+ +WRPD+VL N A
Sbjct: 65 SQIKDMDERNQILTAYLWIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKAD 124
Query: 392 TTAGD-YALRARVSNNGSVSWIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMXNSDEMD 568
+ + + +G ++W + + + +P D Q C FGS N +++D
Sbjct: 125 DESSEPVNTNVVLRYDGLITWDAPAITKSSCVVDVTYFPFDNQQCNLTFGSWTYNGNQVD 184
>AJ243342-1|CAB65091.1| 479|Homo sapiens nicotinic acetylcholine
receptor alpha 9 subunit protein.
Length = 479
Score = 60.1 bits (139), Expect = 1e-08
Identities = 44/180 (24%), Positives = 81/180 (45%), Gaps = 10/180 (5%)
Frame = +2
Query: 59 YSCYQFLLTCAIAS---AAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRH 223
+SC F AS AAE + + + L Y P D+ V+N+TL +
Sbjct: 5 HSCISFCWIYFAASRLRAAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQITL 64
Query: 224 ANIRESESTVRILAD---LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAA 391
+ I++ + +IL ++ W D L+W+ ++ G + + S+ +WRPD+VL N A
Sbjct: 65 SQIKDMDERNQILTAYLWIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKAD 124
Query: 392 TTAGD-YALRARVSNNGSVSWIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMXNSDEMD 568
+ + + +G ++W + + + +P D Q C FGS N +++D
Sbjct: 125 DESSEPVNTNVVLRYDGLITWDAPAITKSSCVVDVTYFPFDNQQCNLTFGSWTYNGNQVD 184
>AC118275-1|AAY40986.1| 479|Homo sapiens unknown protein.
Length = 479
Score = 60.1 bits (139), Expect = 1e-08
Identities = 44/180 (24%), Positives = 81/180 (45%), Gaps = 10/180 (5%)
Frame = +2
Query: 59 YSCYQFLLTCAIAS---AAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRH 223
+SC F AS AAE + + + L Y P D+ V+N+TL +
Sbjct: 5 HSCISFCWIYFAASRLRAAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQITL 64
Query: 224 ANIRESESTVRILAD---LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAA 391
+ I++ + +IL ++ W D L+W+ ++ G + + S+ +WRPD+VL N A
Sbjct: 65 SQIKDMDERNQILTAYLWIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKAD 124
Query: 392 TTAGD-YALRARVSNNGSVSWIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMXNSDEMD 568
+ + + +G ++W + + + +P D Q C FGS N +++D
Sbjct: 125 DESSEPVNTNVVLRYDGLITWDAPAITKSSCVVDVTYFPFDNQQCNLTFGSWTYNGNQVD 184
>X01715-1|CAA25861.1| 520|Homo sapiens acetylcholine receptor gamma
chain precursor protein.
Length = 520
Score = 59.7 bits (138), Expect = 1e-08
Identities = 43/152 (28%), Positives = 72/152 (47%), Gaps = 8/152 (5%)
Frame = +2
Query: 137 MIDSLLATYDRESPPDSKI--VVNLTLHLRHANI---RESESTVRILADLQMNWIDKRLS 301
++ L+ YD P + VVN++L L N+ E E + ++M W D RL
Sbjct: 32 LLADLMQNYDPNLRPAERDSDVVNVSLKLTLTNLISLNEREEALTTNVWIEMQWCDYRLR 91
Query: 302 WNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARV--SNNGSVSWIKRLDIS 472
W+ ++ G V S +WRPD+VL N + AL V S +G + W+
Sbjct: 92 WDPRDYEGLWVLRVPSTMVWRPDIVLENNVDGVF-EVALYCNVLVSPDGCIYWLPPAIFR 150
Query: 473 TPISMQLDXWPNDMQTCTFKFGSRMXNSDEMD 568
+ S+ + +P D Q C+ F S+ +++E+D
Sbjct: 151 SACSISVTYFPFDWQNCSLIFQSQTYSTNEID 182
>AC092165-3|AAY24103.1| 520|Homo sapiens unknown protein.
Length = 520
Score = 59.7 bits (138), Expect = 1e-08
Identities = 43/152 (28%), Positives = 72/152 (47%), Gaps = 8/152 (5%)
Frame = +2
Query: 137 MIDSLLATYDRESPPDSKI--VVNLTLHLRHANI---RESESTVRILADLQMNWIDKRLS 301
++ L+ YD P + VVN++L L N+ E E + ++M W D RL
Sbjct: 32 LLADLMQNYDPNLRPAERDSDVVNVSLKLTLTNLISLNEREEALTTNVWIEMQWCDYRLR 91
Query: 302 WNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARV--SNNGSVSWIKRLDIS 472
W+ ++ G V S +WRPD+VL N + AL V S +G + W+
Sbjct: 92 WDPRDYEGLWVLRVPSTMVWRPDIVLENNVDGVF-EVALYCNVLVSPDGCIYWLPPAIFR 150
Query: 473 TPISMQLDXWPNDMQTCTFKFGSRMXNSDEMD 568
+ S+ + +P D Q C+ F S+ +++E+D
Sbjct: 151 SACSISVTYFPFDWQNCSLIFQSQTYSTNEID 182
>Y00762-1|CAA68731.1| 457|Homo sapiens protein ( Human mRNA for
muscle acetylcholine receptor alpha-subunit. ).
Length = 457
Score = 58.4 bits (135), Expect = 3e-08
Identities = 43/168 (25%), Positives = 76/168 (45%), Gaps = 10/168 (5%)
Frame = +2
Query: 68 YQFLLTCAIASAAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHA---NI 232
+ LL ++ SA + + ++ L Y P D + VV +T+ L+ N+
Sbjct: 4 WPLLLLFSLCSAGLVLGSEHETRLVAKLFKDYSSVVRPVEDHRQVVEVTVGLQLIQLINV 63
Query: 233 RESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDY 409
E V L+ W+D L WN ++G + + SE++WRPD+VL N A GD+
Sbjct: 64 DEVNQIVTTNVRLKQQWVDYNLKWNPDDYGGVKKIHIPSEKIWRPDLVLYNNA---DGDF 120
Query: 410 AL----RARVSNNGSVSWIKRLDISTPISMQLDXWPNDMQTCTFKFGS 541
A+ + + G ++W + + + +P D Q C+ K G+
Sbjct: 121 AIVKFTKVLLQYTGHITWTPPAIFKSYCEIIVTHFPFDEQNCSMKLGT 168
>X02502-1|CAA26344.1| 457|Homo sapiens acetylcholine receptor
protein.
Length = 457
Score = 58.4 bits (135), Expect = 3e-08
Identities = 43/168 (25%), Positives = 76/168 (45%), Gaps = 10/168 (5%)
Frame = +2
Query: 68 YQFLLTCAIASAAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHA---NI 232
+ LL ++ SA + + ++ L Y P D + VV +T+ L+ N+
Sbjct: 4 WPLLLLFSLCSAGLVLGSEHETRLVAKLFKDYSSVVRPVEDHRQVVEVTVGLQLIQLINV 63
Query: 233 RESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDY 409
E V L+ W+D L WN ++G + + SE++WRPD+VL N A GD+
Sbjct: 64 DEVNQIVTTNVRLKQQWVDYNLKWNPDDYGGVKKIHIPSEKIWRPDLVLYNNA---DGDF 120
Query: 410 AL----RARVSNNGSVSWIKRLDISTPISMQLDXWPNDMQTCTFKFGS 541
A+ + + G ++W + + + +P D Q C+ K G+
Sbjct: 121 AIVKFTKVLLQYTGHITWTPPAIFKSYCEIIVTHFPFDEQNCSMKLGT 168
>S77094-1|AAD14247.1| 457|Homo sapiens nicotinic acetylcholine
receptor alpha subunit|AChR protein.
Length = 457
Score = 58.4 bits (135), Expect = 3e-08
Identities = 43/168 (25%), Positives = 76/168 (45%), Gaps = 10/168 (5%)
Frame = +2
Query: 68 YQFLLTCAIASAAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHA---NI 232
+ LL ++ SA + + ++ L Y P D + VV +T+ L+ N+
Sbjct: 4 WPLLLLFSLCSAGLVLGSEHETRLVAKLFKDYSSVVRPVEDHRQVVEVTVGLQLIQLINV 63
Query: 233 RESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDY 409
E V L+ W+D L WN ++G + + SE++WRPD+VL N A GD+
Sbjct: 64 DEVNQIVTTNVRLKQQWVDYNLKWNPDDYGGVKKIHIPSEKIWRPDLVLYNNA---DGDF 120
Query: 410 AL----RARVSNNGSVSWIKRLDISTPISMQLDXWPNDMQTCTFKFGS 541
A+ + + G ++W + + + +P D Q C+ K G+
Sbjct: 121 AIVKFTKVLLQYTGHITWTPPAIFKSYCEIIVTHFPFDEQNCSMKLGT 168
>BC006314-1|AAH06314.1| 269|Homo sapiens CHRNA1 protein protein.
Length = 269
Score = 58.4 bits (135), Expect = 3e-08
Identities = 43/168 (25%), Positives = 76/168 (45%), Gaps = 10/168 (5%)
Frame = +2
Query: 68 YQFLLTCAIASAAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHA---NI 232
+ LL ++ SA + + ++ L Y P D + VV +T+ L+ N+
Sbjct: 4 WPLLLLFSLCSAGLVLGSEHETRLVAKLFKDYSSVVRPVEDHRQVVEVTVGLQLIQLINV 63
Query: 233 RESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDY 409
E V L+ W+D L WN ++G + + SE++WRPD+VL N A GD+
Sbjct: 64 DEVNQIVTTNVRLKQQWVDYNLKWNPDDYGGVKKIHIPSEKIWRPDLVLYNNA---DGDF 120
Query: 410 AL----RARVSNNGSVSWIKRLDISTPISMQLDXWPNDMQTCTFKFGS 541
A+ + + G ++W + + + +P D Q C+ K G+
Sbjct: 121 AIVKFTKVLLQYTGHITWTPPAIFKSYCEIIVTHFPFDEQNCSMKLGT 168
>AF227732-1|AAF61920.1| 470|Homo sapiens nicotinic acetylcholine
receptor alpha 9 subunit protein.
Length = 470
Score = 58.4 bits (135), Expect = 3e-08
Identities = 39/163 (23%), Positives = 75/163 (46%), Gaps = 7/163 (4%)
Frame = +2
Query: 101 AAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHANIRESESTVRILAD-- 268
AAE + + + L Y P D+ V+N+TL + + I++ + +IL
Sbjct: 16 AAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQITLSQIKDMDERNQILTAYL 75
Query: 269 -LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGD-YALRARVSNNG 439
++ W D L+W+ ++ G + + S+ +WRPD+VL N A + + + +G
Sbjct: 76 WIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKADDESSEPVNTNVVLRYDG 135
Query: 440 SVSWIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMXNSDEMD 568
++W + + + +P D Q C FGS N +++D
Sbjct: 136 LITWDAPAITKSSCVVDVTYFPFDNQQCNLTFGSWTYNGNQVD 178
>AC018890-1|AAY14687.1| 457|Homo sapiens unknown protein.
Length = 457
Score = 58.4 bits (135), Expect = 3e-08
Identities = 43/168 (25%), Positives = 76/168 (45%), Gaps = 10/168 (5%)
Frame = +2
Query: 68 YQFLLTCAIASAAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHA---NI 232
+ LL ++ SA + + ++ L Y P D + VV +T+ L+ N+
Sbjct: 4 WPLLLLFSLCSAGLVLGSEHETRLVAKLFKDYSSVVRPVEDHRQVVEVTVGLQLIQLINV 63
Query: 233 RESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDY 409
E V L+ W+D L WN ++G + + SE++WRPD+VL N A GD+
Sbjct: 64 DEVNQIVTTNVRLKQQWVDYNLKWNPDDYGGVKKIHIPSEKIWRPDLVLYNNA---DGDF 120
Query: 410 AL----RARVSNNGSVSWIKRLDISTPISMQLDXWPNDMQTCTFKFGS 541
A+ + + G ++W + + + +P D Q C+ K G+
Sbjct: 121 AIVKFTKVLLQYTGHITWTPPAIFKSYCEIIVTHFPFDEQNCSMKLGT 168
>S77554-1|AAB33983.1| 474|Homo sapiens GABAA receptor beta 2
subunit protein.
Length = 474
Score = 56.8 bits (131), Expect = 9e-08
Identities = 44/182 (24%), Positives = 79/182 (43%), Gaps = 10/182 (5%)
Frame = +2
Query: 56 YYSCYQFLLTCAIASAAECENATSLSLM---IDSLLATYDRESPPD---SKIVVNLTLHL 217
Y+ + F L A A + +++SL+ +D LL YD PD + V + + +
Sbjct: 9 YFGIWSFPLIIAAVCAQSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDI 68
Query: 218 RHAN-IRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAAT 394
+ + E + Q W DKRLS+N + +++LW PD LN +
Sbjct: 69 ASIDMVSEVNMDYTLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLNDKKS 128
Query: 395 TAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMXNSDEM 565
++ R+ +G+V + R+ + M L +P D Q CT + S +D++
Sbjct: 129 FVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDI 188
Query: 566 DF 571
+F
Sbjct: 189 EF 190
>S77553-1|AAB33982.1| 512|Homo sapiens GABAA receptor beta 2
subunit protein.
Length = 512
Score = 56.8 bits (131), Expect = 9e-08
Identities = 44/182 (24%), Positives = 79/182 (43%), Gaps = 10/182 (5%)
Frame = +2
Query: 56 YYSCYQFLLTCAIASAAECENATSLSLM---IDSLLATYDRESPPD---SKIVVNLTLHL 217
Y+ + F L A A + +++SL+ +D LL YD PD + V + + +
Sbjct: 9 YFGIWSFPLIIAAVCAQSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDI 68
Query: 218 RHAN-IRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAAT 394
+ + E + Q W DKRLS+N + +++LW PD LN +
Sbjct: 69 ASIDMVSEVNMDYTLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLNDKKS 128
Query: 395 TAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMXNSDEM 565
++ R+ +G+V + R+ + M L +P D Q CT + S +D++
Sbjct: 129 FVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDI 188
Query: 566 DF 571
+F
Sbjct: 189 EF 190
>S67368-1|AAB29370.1| 474|Homo sapiens gamma-aminobutyric acid A
receptor beta 2 subunit protein.
Length = 474
Score = 56.8 bits (131), Expect = 9e-08
Identities = 44/182 (24%), Positives = 79/182 (43%), Gaps = 10/182 (5%)
Frame = +2
Query: 56 YYSCYQFLLTCAIASAAECENATSLSLM---IDSLLATYDRESPPD---SKIVVNLTLHL 217
Y+ + F L A A + +++SL+ +D LL YD PD + V + + +
Sbjct: 9 YFGIWSFPLIIAAVCAQSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDI 68
Query: 218 RHAN-IRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAAT 394
+ + E + Q W DKRLS+N + +++LW PD LN +
Sbjct: 69 ASIDMVSEVNMDYTLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLNDKKS 128
Query: 395 TAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMXNSDEM 565
++ R+ +G+V + R+ + M L +P D Q CT + S +D++
Sbjct: 129 FVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDI 188
Query: 566 DF 571
+F
Sbjct: 189 EF 190
>BC105639-1|AAI05640.1| 474|Homo sapiens GABRB2 protein protein.
Length = 474
Score = 56.8 bits (131), Expect = 9e-08
Identities = 44/182 (24%), Positives = 79/182 (43%), Gaps = 10/182 (5%)
Frame = +2
Query: 56 YYSCYQFLLTCAIASAAECENATSLSLM---IDSLLATYDRESPPD---SKIVVNLTLHL 217
Y+ + F L A A + +++SL+ +D LL YD PD + V + + +
Sbjct: 9 YFGIWSFPLIIAAVCAQSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDI 68
Query: 218 RHAN-IRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAAT 394
+ + E + Q W DKRLS+N + +++LW PD LN +
Sbjct: 69 ASIDMVSEVNMDYTLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLNDKKS 128
Query: 395 TAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMXNSDEM 565
++ R+ +G+V + R+ + M L +P D Q CT + S +D++
Sbjct: 129 FVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDI 188
Query: 566 DF 571
+F
Sbjct: 189 EF 190
>BC099719-1|AAH99719.1| 474|Homo sapiens GABRB2 protein protein.
Length = 474
Score = 56.8 bits (131), Expect = 9e-08
Identities = 44/182 (24%), Positives = 79/182 (43%), Gaps = 10/182 (5%)
Frame = +2
Query: 56 YYSCYQFLLTCAIASAAECENATSLSLM---IDSLLATYDRESPPD---SKIVVNLTLHL 217
Y+ + F L A A + +++SL+ +D LL YD PD + V + + +
Sbjct: 9 YFGIWSFPLIIAAVCAQSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDI 68
Query: 218 RHAN-IRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAAT 394
+ + E + Q W DKRLS+N + +++LW PD LN +
Sbjct: 69 ASIDMVSEVNMDYTLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLNDKKS 128
Query: 395 TAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMXNSDEM 565
++ R+ +G+V + R+ + M L +P D Q CT + S +D++
Sbjct: 129 FVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDI 188
Query: 566 DF 571
+F
Sbjct: 189 EF 190
>BC099705-1|AAH99705.1| 474|Homo sapiens GABRB2 protein protein.
Length = 474
Score = 56.8 bits (131), Expect = 9e-08
Identities = 44/182 (24%), Positives = 79/182 (43%), Gaps = 10/182 (5%)
Frame = +2
Query: 56 YYSCYQFLLTCAIASAAECENATSLSLM---IDSLLATYDRESPPD---SKIVVNLTLHL 217
Y+ + F L A A + +++SL+ +D LL YD PD + V + + +
Sbjct: 9 YFGIWSFPLIIAAVCAQSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDI 68
Query: 218 RHAN-IRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAAT 394
+ + E + Q W DKRLS+N + +++LW PD LN +
Sbjct: 69 ASIDMVSEVNMDYTLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLNDKKS 128
Query: 395 TAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMXNSDEM 565
++ R+ +G+V + R+ + M L +P D Q CT + S +D++
Sbjct: 129 FVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDI 188
Query: 566 DF 571
+F
Sbjct: 189 EF 190
>AJ001935-1|CAA05108.1| 504|Homo sapiens CHRNB2 protein.
Length = 504
Score = 56.4 bits (130), Expect = 1e-07
Identities = 46/171 (26%), Positives = 73/171 (42%), Gaps = 4/171 (2%)
Frame = +2
Query: 68 YQFLLTCAIASAAECENATSLSLMIDSLLATYDRESPPDSKIV-VNLTLHLRHA-NIRES 241
+ L C+ A+ E L+ S R + S++V V L + L ++ E
Sbjct: 14 FGLLRLCSGVWGADTEERLVEHLLDPSRYNKLIRPATNGSELVTVQLMVSLAQLISVHER 73
Query: 242 ESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYAL 415
E + L W D RL+W E+ + S+ +W PDVVL N A +
Sbjct: 74 EQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLPDVVLYNNADGMYEVSFYS 133
Query: 416 RARVSNNGSVSWIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMXNSDEMD 568
A VS +GS+ W+ + +++ +P D Q CT KF S + E+D
Sbjct: 134 NAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRSWTYDRTEID 184
>Y08415-1|CAA69692.1| 502|Homo sapiens nicotinic acetylcholine
receptor beta2 subunit precursor protein.
Length = 502
Score = 56.0 bits (129), Expect = 2e-07
Identities = 37/129 (28%), Positives = 58/129 (44%), Gaps = 3/129 (2%)
Frame = +2
Query: 191 IVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 364
+ V L + L ++ E E + L W D RL+W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 365 DVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDXWPNDMQTCTFKFGS 541
DVVL N A + A VS +GS+ W+ + +++ +P D Q CT KF S
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRS 175
Query: 542 RMXNSDEMD 568
+ E+D
Sbjct: 176 WTYDRTEID 184
>X53179-1|CAA37320.1| 502|Homo sapiens precursor peptide (AA -25 to
477) protein.
Length = 502
Score = 56.0 bits (129), Expect = 2e-07
Identities = 37/129 (28%), Positives = 58/129 (44%), Gaps = 3/129 (2%)
Frame = +2
Query: 191 IVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 364
+ V L + L ++ E E + L W D RL+W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 365 DVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDXWPNDMQTCTFKFGS 541
DVVL N A + A VS +GS+ W+ + +++ +P D Q CT KF S
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRS 175
Query: 542 RMXNSDEMD 568
+ E+D
Sbjct: 176 WTYDRTEID 184
>U62437-1|AAB40115.1| 502|Homo sapiens nicotinic acetylcholine
receptor beta2 subunit precursor protein.
Length = 502
Score = 56.0 bits (129), Expect = 2e-07
Identities = 37/129 (28%), Positives = 58/129 (44%), Gaps = 3/129 (2%)
Frame = +2
Query: 191 IVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 364
+ V L + L ++ E E + L W D RL+W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 365 DVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDXWPNDMQTCTFKFGS 541
DVVL N A + A VS +GS+ W+ + +++ +P D Q CT KF S
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRS 175
Query: 542 RMXNSDEMD 568
+ E+D
Sbjct: 176 WTYDRTEID 184
>BC075041-1|AAH75041.1| 502|Homo sapiens cholinergic receptor,
nicotinic, beta 2 (neuronal) protein.
Length = 502
Score = 56.0 bits (129), Expect = 2e-07
Identities = 37/129 (28%), Positives = 58/129 (44%), Gaps = 3/129 (2%)
Frame = +2
Query: 191 IVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 364
+ V L + L ++ E E + L W D RL+W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 365 DVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDXWPNDMQTCTFKFGS 541
DVVL N A + A VS +GS+ W+ + +++ +P D Q CT KF S
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRS 175
Query: 542 RMXNSDEMD 568
+ E+D
Sbjct: 176 WTYDRTEID 184
>BC075040-1|AAH75040.1| 502|Homo sapiens cholinergic receptor,
nicotinic, beta 2 (neuronal) protein.
Length = 502
Score = 56.0 bits (129), Expect = 2e-07
Identities = 37/129 (28%), Positives = 58/129 (44%), Gaps = 3/129 (2%)
Frame = +2
Query: 191 IVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 364
+ V L + L ++ E E + L W D RL+W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 365 DVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDXWPNDMQTCTFKFGS 541
DVVL N A + A VS +GS+ W+ + +++ +P D Q CT KF S
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRS 175
Query: 542 RMXNSDEMD 568
+ E+D
Sbjct: 176 WTYDRTEID 184
>AL592078-3|CAI16184.1| 502|Homo sapiens cholinergic receptor,
nicotinic, beta 2 (neuronal) protein.
Length = 502
Score = 56.0 bits (129), Expect = 2e-07
Identities = 37/129 (28%), Positives = 58/129 (44%), Gaps = 3/129 (2%)
Frame = +2
Query: 191 IVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 364
+ V L + L ++ E E + L W D RL+W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 365 DVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDXWPNDMQTCTFKFGS 541
DVVL N A + A VS +GS+ W+ + +++ +P D Q CT KF S
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRS 175
Query: 542 RMXNSDEMD 568
+ E+D
Sbjct: 176 WTYDRTEID 184
>AF077186-1|AAD45422.1| 502|Homo sapiens neuronal nicotinic
acetylcholine receptor beta 2 protein.
Length = 502
Score = 56.0 bits (129), Expect = 2e-07
Identities = 37/129 (28%), Positives = 58/129 (44%), Gaps = 3/129 (2%)
Frame = +2
Query: 191 IVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 364
+ V L + L ++ E E + L W D RL+W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 365 DVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDXWPNDMQTCTFKFGS 541
DVVL N A + A VS +GS+ W+ + +++ +P D Q CT KF S
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRS 175
Query: 542 RMXNSDEMD 568
+ E+D
Sbjct: 176 WTYDRTEID 184
>X55019-1|CAA38759.1| 517|Homo sapiens acetylcholine receptor delta
subunit protein.
Length = 517
Score = 55.6 bits (128), Expect = 2e-07
Identities = 38/142 (26%), Positives = 66/142 (46%), Gaps = 7/142 (4%)
Frame = +2
Query: 161 YDRESPP----DSKIVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEWG- 322
Y++E P + + V L L L + +++E E T+ ++ W D RL WNA E+G
Sbjct: 38 YNKELRPVAHKEESVDVALALTLSNLISLKEVEETLTTNVWIEHGWTDNRLKWNAEEFGN 97
Query: 323 CSTWLVSSERLWRPDVVL-LNAAATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDX 499
S + + +W P++VL N + Y+ V + G V W+ + + +
Sbjct: 98 ISVLRLPPDMVWLPEIVLENNNDGSFQISYSCNVLVYHYGFVYWLPPAIFRSSCPISVTY 157
Query: 500 WPNDMQTCTFKFGSRMXNSDEM 565
+P D Q C+ KF S + E+
Sbjct: 158 FPFDWQNCSLKFSSLKYTAKEI 179
>DQ644022-1|ABG35128.1| 456|Homo sapiens 5-HT3 receptor subunit E
splice variant HTR3Ea protein.
Length = 456
Score = 55.6 bits (128), Expect = 2e-07
Identities = 28/100 (28%), Positives = 49/100 (49%), Gaps = 1/100 (1%)
Frame = +2
Query: 269 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 445
L+M W + +SWN E G + ++++ LW PD+ ++ L A VSN G +
Sbjct: 91 LEMVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEGRI 150
Query: 446 SWIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMXNSDEM 565
+ K + + + ++ + +P D Q CT F S + D M
Sbjct: 151 RYKKPMKVDSICNLDIFYFPFDQQNCTLTFSSFLYTVDSM 190
>BC101185-1|AAI01186.1| 374|Homo sapiens HTR3E protein protein.
Length = 374
Score = 55.6 bits (128), Expect = 2e-07
Identities = 28/100 (28%), Positives = 49/100 (49%), Gaps = 1/100 (1%)
Frame = +2
Query: 269 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 445
L+M W + +SWN E G + ++++ LW PD+ ++ L A VSN G +
Sbjct: 20 LEMVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEGRI 79
Query: 446 SWIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMXNSDEM 565
+ K + + + ++ + +P D Q CT F S + D M
Sbjct: 80 RYKKPMKVDSICNLDIFYFPFDQQNCTLTFSSFLYTVDSM 119
>BC101183-1|AAI01184.1| 471|Homo sapiens 5-hydroxytryptamine
(serotonin) receptor 3, family member E protein.
Length = 471
Score = 55.6 bits (128), Expect = 2e-07
Identities = 28/100 (28%), Positives = 49/100 (49%), Gaps = 1/100 (1%)
Frame = +2
Query: 269 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 445
L+M W + +SWN E G + ++++ LW PD+ ++ L A VSN G +
Sbjct: 106 LEMVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEGRI 165
Query: 446 SWIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMXNSDEM 565
+ K + + + ++ + +P D Q CT F S + D M
Sbjct: 166 RYKKPMKVDSICNLDIFYFPFDQQNCTLTFSSFLYTVDSM 205
>BC101182-1|AAI01183.1| 471|Homo sapiens 5-hydroxytryptamine
(serotonin) receptor 3, family member E protein.
Length = 471
Score = 55.6 bits (128), Expect = 2e-07
Identities = 28/100 (28%), Positives = 49/100 (49%), Gaps = 1/100 (1%)
Frame = +2
Query: 269 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 445
L+M W + +SWN E G + ++++ LW PD+ ++ L A VSN G +
Sbjct: 106 LEMVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEGRI 165
Query: 446 SWIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMXNSDEM 565
+ K + + + ++ + +P D Q CT F S + D M
Sbjct: 166 RYKKPMKVDSICNLDIFYFPFDQQNCTLTFSSFLYTVDSM 205
>BC093925-1|AAH93925.1| 517|Homo sapiens cholinergic receptor,
nicotinic, delta protein.
Length = 517
Score = 55.6 bits (128), Expect = 2e-07
Identities = 38/142 (26%), Positives = 66/142 (46%), Gaps = 7/142 (4%)
Frame = +2
Query: 161 YDRESPP----DSKIVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEWG- 322
Y++E P + + V L L L + +++E E T+ ++ W D RL WNA E+G
Sbjct: 38 YNKELRPVAHKEESVDVALALTLSNLISLKEVEETLTTNVWIEHGWTDNRLKWNAEEFGN 97
Query: 323 CSTWLVSSERLWRPDVVL-LNAAATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDX 499
S + + +W P++VL N + Y+ V + G V W+ + + +
Sbjct: 98 ISVLRLPPDMVWLPEIVLENNNDGSFQISYSCNVLVYHYGFVYWLPPAIFRSSCPISVTY 157
Query: 500 WPNDMQTCTFKFGSRMXNSDEM 565
+P D Q C+ KF S + E+
Sbjct: 158 FPFDWQNCSLKFSSLKYTAKEI 179
>BC093923-1|AAH93923.1| 517|Homo sapiens cholinergic receptor,
nicotinic, delta protein.
Length = 517
Score = 55.6 bits (128), Expect = 2e-07
Identities = 38/142 (26%), Positives = 66/142 (46%), Gaps = 7/142 (4%)
Frame = +2
Query: 161 YDRESPP----DSKIVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEWG- 322
Y++E P + + V L L L + +++E E T+ ++ W D RL WNA E+G
Sbjct: 38 YNKELRPVAHKEESVDVALALTLSNLISLKEVEETLTTNVWIEHGWTDNRLKWNAEEFGN 97
Query: 323 CSTWLVSSERLWRPDVVL-LNAAATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDX 499
S + + +W P++VL N + Y+ V + G V W+ + + +
Sbjct: 98 ISVLRLPPDMVWLPEIVLENNNDGSFQISYSCNVLVYHYGFVYWLPPAIFRSSCPISVTY 157
Query: 500 WPNDMQTCTFKFGSRMXNSDEM 565
+P D Q C+ KF S + E+
Sbjct: 158 FPFDWQNCSLKFSSLKYTAKEI 179
>AY159813-1|AAO38167.2| 471|Homo sapiens 5-hydroxytryptamine
serotonin receptor 3E protein.
Length = 471
Score = 55.6 bits (128), Expect = 2e-07
Identities = 28/100 (28%), Positives = 49/100 (49%), Gaps = 1/100 (1%)
Frame = +2
Query: 269 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 445
L+M W + +SWN E G + ++++ LW PD+ ++ L A VSN G +
Sbjct: 106 LEMVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEGRI 165
Query: 446 SWIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMXNSDEM 565
+ K + + + ++ + +P D Q CT F S + D M
Sbjct: 166 RYKKPMKVDSICNLDIFYFPFDQQNCTLTFSSFLYTVDSM 205
>AC092165-2|AAY24102.1| 517|Homo sapiens unknown protein.
Length = 517
Score = 55.6 bits (128), Expect = 2e-07
Identities = 38/142 (26%), Positives = 66/142 (46%), Gaps = 7/142 (4%)
Frame = +2
Query: 161 YDRESPP----DSKIVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEWG- 322
Y++E P + + V L L L + +++E E T+ ++ W D RL WNA E+G
Sbjct: 38 YNKELRPVAHKEESVDVALALTLSNLISLKEVEETLTTNVWIEHGWTDNRLKWNAEEFGN 97
Query: 323 CSTWLVSSERLWRPDVVL-LNAAATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDX 499
S + + +W P++VL N + Y+ V + G V W+ + + +
Sbjct: 98 ISVLRLPPDMVWLPEIVLENNNDGSFQISYSCNVLVYHYGFVYWLPPAIFRSSCPISVTY 157
Query: 500 WPNDMQTCTFKFGSRMXNSDEM 565
+P D Q C+ KF S + E+
Sbjct: 158 FPFDWQNCSLKFSSLKYTAKEI 179
>AJ295237-1|CAC16144.1| 450|Homo sapiens neuronal nicotinic
acetylcholine receptor subunit4 protein.
Length = 450
Score = 55.2 bits (127), Expect = 3e-07
Identities = 44/165 (26%), Positives = 72/165 (43%), Gaps = 10/165 (6%)
Frame = +2
Query: 104 AEC---ENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHANIRESESTVRILAD 268
AEC E +L L D L A Y P D+ +N+TL + + I + + ++L
Sbjct: 20 AECLGAEGRLALKLFRD-LFANYTSALRPVADTDQTLNVTLEVTLSQIIDMDERNQVLTL 78
Query: 269 ---LQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSN 433
++ W D L W+ +G + S +WRPD+VL N A A G + + +
Sbjct: 79 YLWIRQEWTDAYLRWDPNAYGGLDAIRIPSSLVWRPDIVLYNKADAQPPGSASTNVVLRH 138
Query: 434 NGSVSWIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMXNSDEMD 568
+G+V W + + + +P D Q C FGS ++D
Sbjct: 139 DGAVRWDAPAITRSSCRVDVAAFPFDAQHCGLTFGSWTHGGHQLD 183
>AJ278118-1|CAC20435.1| 450|Homo sapiens neuronal nicotinic
acetylcholine alpha10 subunit protein.
Length = 450
Score = 55.2 bits (127), Expect = 3e-07
Identities = 44/165 (26%), Positives = 72/165 (43%), Gaps = 10/165 (6%)
Frame = +2
Query: 104 AEC---ENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHANIRESESTVRILAD 268
AEC E +L L D L A Y P D+ +N+TL + + I + + ++L
Sbjct: 20 AECLGAEGRLALKLFRD-LFANYTSALRPVADTDQTLNVTLEVTLSQIIDMDERNQVLTL 78
Query: 269 ---LQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSN 433
++ W D L W+ +G + S +WRPD+VL N A A G + + +
Sbjct: 79 YLWIRQEWTDAYLRWDPNAYGGLDAIRIPSSLVWRPDIVLYNKADAQPPGSASTNVVLRH 138
Query: 434 NGSVSWIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMXNSDEMD 568
+G+V W + + + +P D Q C FGS ++D
Sbjct: 139 DGAVRWDAPAITRSSCRVDVAAFPFDAQHCGLTFGSWTHGGHQLD 183
>AF327367-1|AAK14333.1| 450|Homo sapiens nicotinic acetylcholine
receptor subunit alpha 10 protein.
Length = 450
Score = 55.2 bits (127), Expect = 3e-07
Identities = 44/165 (26%), Positives = 72/165 (43%), Gaps = 10/165 (6%)
Frame = +2
Query: 104 AEC---ENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHANIRESESTVRILAD 268
AEC E +L L D L A Y P D+ +N+TL + + I + + ++L
Sbjct: 20 AECLGAEGRLALKLFRD-LFANYTSALRPVADTDQTLNVTLEVTLSQIIDMDERNQVLTL 78
Query: 269 ---LQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSN 433
++ W D L W+ +G + S +WRPD+VL N A A G + + +
Sbjct: 79 YLWIRQEWTDAYLRWDPNAYGGLDAIRIPSSLVWRPDIVLYNKADAQPPGSASTNVVLRH 138
Query: 434 NGSVSWIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMXNSDEMD 568
+G+V W + + + +P D Q C FGS ++D
Sbjct: 139 DGAVRWDAPAITRSSCRVDVAAFPFDAQHCGLTFGSWTHGGHQLD 183
>AF199235-1|AAG00795.2| 450|Homo sapiens nicotinic acetylcholine
receptor subunit alpha 10 protein.
Length = 450
Score = 55.2 bits (127), Expect = 3e-07
Identities = 44/165 (26%), Positives = 72/165 (43%), Gaps = 10/165 (6%)
Frame = +2
Query: 104 AEC---ENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHANIRESESTVRILAD 268
AEC E +L L D L A Y P D+ +N+TL + + I + + ++L
Sbjct: 20 AECLGAEGRLALKLFRD-LFANYTSALRPVADTDQTLNVTLEVTLSQIIDMDERNQVLTL 78
Query: 269 ---LQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSN 433
++ W D L W+ +G + S +WRPD+VL N A A G + + +
Sbjct: 79 YLWIRQEWTDAYLRWDPNAYGGLDAIRIPSSLVWRPDIVLYNKADAQPPGSASTNVVLRH 138
Query: 434 NGSVSWIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMXNSDEMD 568
+G+V W + + + +P D Q C FGS ++D
Sbjct: 139 DGAVRWDAPAITRSSCRVDVAAFPFDAQHCGLTFGSWTHGGHQLD 183
>BC131799-1|AAI31800.1| 447|Homo sapiens 5-hydroxytryptamine
(serotonin) receptor 3, family member C protein.
Length = 447
Score = 54.8 bits (126), Expect = 4e-07
Identities = 27/103 (26%), Positives = 51/103 (49%), Gaps = 1/103 (0%)
Frame = +2
Query: 269 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 445
+ + W + ++WN E G + V +E LW PD+ ++ + L A +S+ G +
Sbjct: 91 MDLVWDNPFINWNPKECVGINKLTVLAENLWLPDIFIVESMDVDQTPSGLTAYISSEGRI 150
Query: 446 SWIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMXNSDEMDFG 574
+ K + +++ ++ + +P D Q CTF F S + D M G
Sbjct: 151 KYDKPMRVTSICNLDIFYFPFDQQNCTFTFSSFLYTVDSMLLG 193
>AF459285-1|AAL66182.1| 447|Homo sapiens 5-hydroxytryptamine
receptor 3 subunit C protein.
Length = 447
Score = 54.4 bits (125), Expect = 5e-07
Identities = 27/103 (26%), Positives = 50/103 (48%), Gaps = 1/103 (0%)
Frame = +2
Query: 269 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 445
+ + W + ++WN E G + V +E LW PD+ ++ + L A +S+ G +
Sbjct: 91 MDLVWDNPFINWNPKECVGINKLTVLAENLWLPDIFIVESMDVDQTPSGLTAYISSEGRI 150
Query: 446 SWIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMXNSDEMDFG 574
+ K + +++ + + +P D Q CTF F S + D M G
Sbjct: 151 KYDKPMRVTSICKLDIFYFPFDQQNCTFTFSSFLYTVDSMLLG 193
>AY349353-1|AAQ93477.1| 456|Homo sapiens 5-HT3c1 serotonin
receptor-like protein protein.
Length = 456
Score = 53.6 bits (123), Expect = 9e-07
Identities = 28/102 (27%), Positives = 49/102 (48%), Gaps = 1/102 (0%)
Frame = +2
Query: 263 ADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNG 439
A L + W + +SWN E G + ++++ LW PD+ ++ L A VSN G
Sbjct: 89 AILDVVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEG 148
Query: 440 SVSWIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMXNSDEM 565
+ + K + + + ++ + +P D Q CT F S + D M
Sbjct: 149 RIRYKKPMKVDSICNLDIFYFPFDQQNCTLTFSSFLYTVDSM 190
>AY349352-1|AAQ93476.1| 441|Homo sapiens 5-HT3c1 serotonin
receptor-like protein protein.
Length = 441
Score = 53.6 bits (123), Expect = 9e-07
Identities = 28/102 (27%), Positives = 49/102 (48%), Gaps = 1/102 (0%)
Frame = +2
Query: 263 ADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNG 439
A L + W + +SWN E G + ++++ LW PD+ ++ L A VSN G
Sbjct: 74 AILDVVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEG 133
Query: 440 SVSWIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMXNSDEM 565
+ + K + + + ++ + +P D Q CT F S + D M
Sbjct: 134 RIRYKKPMKVDSICNLDIFYFPFDQQNCTLTFSSFLYTVDSM 175
>BC110597-1|AAI10598.1| 411|Homo sapiens ligand-gated ion channel,
zinc activated 1 protein.
Length = 411
Score = 52.8 bits (121), Expect = 2e-06
Identities = 28/101 (27%), Positives = 47/101 (46%)
Frame = +2
Query: 269 LQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVS 448
L+++W+D RL+WN + E LW P + +L A D + +ARV +G V
Sbjct: 86 LRLSWLDTRLAWNTSAHPRHAITLPWESLWTPRLTILEALWVDWRDQSPQARVDQDGHVK 145
Query: 449 WIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMXNSDEMDF 571
L T + +L +P D C+ F + + E++F
Sbjct: 146 LNLALTTETNCNFELLHFPRDHSNCSLSFYALSNTAMELEF 186
>AF512521-1|AAO20969.1| 411|Homo sapiens ligand-gated ion channel
subunit protein.
Length = 411
Score = 52.8 bits (121), Expect = 2e-06
Identities = 28/101 (27%), Positives = 47/101 (46%)
Frame = +2
Query: 269 LQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVS 448
L+++W+D RL+WN + E LW P + +L A D + +ARV +G V
Sbjct: 86 LRLSWLDTRLAWNTSAHPRHAITLPWESLWTPRLTILEALWVDWRDQSPQARVDQDGHVK 145
Query: 449 WIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMXNSDEMDF 571
L T + +L +P D C+ F + + E++F
Sbjct: 146 LNLALTTETNCNFELLHFPRDHSNCSLSFYALSNTAMELEF 186
>AB223030-1|BAE19924.1| 411|Homo sapiens ligand-gated ion-channel
receptor L2 protein.
Length = 411
Score = 52.4 bits (120), Expect = 2e-06
Identities = 28/101 (27%), Positives = 47/101 (46%)
Frame = +2
Query: 269 LQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVS 448
L+++W+D RL+WN + E LW P + +L A D + +ARV +G V
Sbjct: 86 LRLSWLDTRLAWNTSAHPRHAITLPWESLWTPRLTILEALWVDWRDQSPQARVDQDGHVK 145
Query: 449 WIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMXNSDEMDF 571
L T + +L +P D C+ F + + E++F
Sbjct: 146 LNLALATETNCNFELLHFPRDHSNCSLSFYALSNTAMELEF 186
>M59216-1|AAA35862.1| 474|Homo sapiens gamma-aminobutyric acid
receptor beta-1 subunit protein.
Length = 474
Score = 52.0 bits (119), Expect = 3e-06
Identities = 40/171 (23%), Positives = 73/171 (42%), Gaps = 7/171 (4%)
Frame = +2
Query: 80 LTCAIASAAECENATSLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESES 247
+ C S E N + + +D LL YD PD + V + + + + + E
Sbjct: 21 MVCCAHSTNEPSNMSYVKETVDRLLKGYDIRLRPDFGGPPVDVGMRIDVASIDMVSEVNM 80
Query: 248 TVRILADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR--- 418
+ Q +W DKRLS++ + +++LW PD LN + ++
Sbjct: 81 DYTLTMYFQQSWKDKRLSYSGIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRM 140
Query: 419 ARVSNNGSVSWIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMXNSDEMDF 571
R+ +G+V + R+ + M L +P D Q CT + S +D+++F
Sbjct: 141 IRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEF 191
>Z23141-1|CAA80672.1| 479|Homo sapiens cholinergic receptor,
nicotinic, alpha polypeptide 7 protein.
Length = 479
Score = 51.6 bits (118), Expect = 4e-06
Identities = 27/93 (29%), Positives = 46/93 (49%), Gaps = 2/93 (2%)
Frame = +2
Query: 269 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSNNGS 442
LQM+W D L WN E+ G T ++W+PD++L N+A + V+++G
Sbjct: 55 LQMSWTDHYLQWNVSEYPGVKTVRFPDGQIWKPDILLYNSADERFDATFHTNVLVNSSGH 114
Query: 443 VSWIKRLDISTPISMQLDXWPNDMQTCTFKFGS 541
++ + + + +P D+Q C KFGS
Sbjct: 115 CQYLPPGIFKSSCYIDVRWFPFDVQHCKLKFGS 147
>Y08420-1|CAA69697.1| 502|Homo sapiens nicotinic acetylcholine
receptor alpha7 subunit precursor protein.
Length = 502
Score = 51.6 bits (118), Expect = 4e-06
Identities = 27/93 (29%), Positives = 46/93 (49%), Gaps = 2/93 (2%)
Frame = +2
Query: 269 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSNNGS 442
LQM+W D L WN E+ G T ++W+PD++L N+A + V+++G
Sbjct: 78 LQMSWTDHYLQWNVSEYPGVKTVRFPDGQIWKPDILLYNSADERFDATFHTNVLVNSSGH 137
Query: 443 VSWIKRLDISTPISMQLDXWPNDMQTCTFKFGS 541
++ + + + +P D+Q C KFGS
Sbjct: 138 CQYLPPGIFKSSCYIDVRWFPFDVQHCKLKFGS 170
>X70297-1|CAA49778.1| 502|Homo sapiens neuronal nicotinic
acetylocholine receptor alpha-7 subunit protein.
Length = 502
Score = 51.6 bits (118), Expect = 4e-06
Identities = 27/93 (29%), Positives = 46/93 (49%), Gaps = 2/93 (2%)
Frame = +2
Query: 269 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSNNGS 442
LQM+W D L WN E+ G T ++W+PD++L N+A + V+++G
Sbjct: 78 LQMSWTDHYLQWNVSEYPGVKTVRFPDGQIWKPDILLYNSADERFDATFHTNVLVNSSGH 137
Query: 443 VSWIKRLDISTPISMQLDXWPNDMQTCTFKFGS 541
++ + + + +P D+Q C KFGS
Sbjct: 138 CQYLPPGIFKSSCYIDVRWFPFDVQHCKLKFGS 170
>U62436-1|AAB40114.1| 502|Homo sapiens nicotinic acetylcholine
receptor alpha7 subunit precursor protein.
Length = 502
Score = 51.6 bits (118), Expect = 4e-06
Identities = 27/93 (29%), Positives = 46/93 (49%), Gaps = 2/93 (2%)
Frame = +2
Query: 269 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSNNGS 442
LQM+W D L WN E+ G T ++W+PD++L N+A + V+++G
Sbjct: 78 LQMSWTDHYLQWNVSEYPGVKTVRFPDGQIWKPDILLYNSADERFDATFHTNVLVNSSGH 137
Query: 443 VSWIKRLDISTPISMQLDXWPNDMQTCTFKFGS 541
++ + + + +P D+Q C KFGS
Sbjct: 138 CQYLPPGIFKSSCYIDVRWFPFDVQHCKLKFGS 170
>AJ586911-1|CAE52911.1| 502|Homo sapiens nicotinic acetylcholine
alpha-7 subunit protein.
Length = 502
Score = 51.6 bits (118), Expect = 4e-06
Identities = 27/93 (29%), Positives = 46/93 (49%), Gaps = 2/93 (2%)
Frame = +2
Query: 269 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSNNGS 442
LQM+W D L WN E+ G T ++W+PD++L N+A + V+++G
Sbjct: 78 LQMSWTDHYLQWNVSEYPGVKTVRFPDGQIWKPDILLYNSADERFDATFHTNVLVNSSGH 137
Query: 443 VSWIKRLDISTPISMQLDXWPNDMQTCTFKFGS 541
++ + + + +P D+Q C KFGS
Sbjct: 138 CQYLPPGIFKSSCYIDVRWFPFDVQHCKLKFGS 170
>X14767-1|CAA32875.1| 474|Homo sapiens GABA-A receptor beta 1
subunit protein.
Length = 474
Score = 51.2 bits (117), Expect = 5e-06
Identities = 40/171 (23%), Positives = 72/171 (42%), Gaps = 7/171 (4%)
Frame = +2
Query: 80 LTCAIASAAECENATSLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESES 247
+ C S E N + +D LL YD PD + V + + + + + E
Sbjct: 21 MVCCAHSTNEPSNMPYVKETVDRLLKGYDIRLRPDFGGPPVDVGMRIDVASIDMVSEVNM 80
Query: 248 TVRILADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR--- 418
+ Q +W DKRLS++ + +++LW PD LN + ++
Sbjct: 81 DYTLTMYFQQSWKDKRLSYSGIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRM 140
Query: 419 ARVSNNGSVSWIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMXNSDEMDF 571
R+ +G+V + R+ + M L +P D Q CT + S +D+++F
Sbjct: 141 IRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEF 191
>BC111802-1|AAI11803.1| 465|Homo sapiens CHRNG protein protein.
Length = 465
Score = 51.2 bits (117), Expect = 5e-06
Identities = 40/133 (30%), Positives = 62/133 (46%), Gaps = 7/133 (5%)
Frame = +2
Query: 77 LLTCAIASAAECENATSLSLMIDSLLATYDRESPPDSKI--VVNLTLHLRHANI---RES 241
LL A+ A+ N L+ D L+ YD P + VVN++L L N+ E
Sbjct: 11 LLLLAVCLGAQGRNQEE-RLLAD-LMQNYDPNLRPAERDSDVVNVSLKLTLTNLISLNER 68
Query: 242 ESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAAT-TAGDYAL 415
E + ++M W D RL W+ ++ G V S +WRPD+VL N + T + + L
Sbjct: 69 EEALTTNVWIEMQWCDYRLRWDPRDYEGLWVLRVPSTMVWRPDIVLENKSQTYSTNEIDL 128
Query: 416 RARVSNNGSVSWI 454
+ + S+ WI
Sbjct: 129 QLSQEDGQSIEWI 141
>U40583-1|AAA83561.1| 502|Homo sapiens alpha 7 neuronal nicotinic
acetylcholine receptor protein.
Length = 502
Score = 50.4 bits (115), Expect = 8e-06
Identities = 27/93 (29%), Positives = 45/93 (48%), Gaps = 2/93 (2%)
Frame = +2
Query: 269 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSNNGS 442
LQM+W D L WN E+ G T ++W+PD++L N+A + V+ +G
Sbjct: 78 LQMSWTDHYLQWNVSEYPGVKTVRFPDGQIWKPDILLYNSADERFDATFHTNVLVNPSGH 137
Query: 443 VSWIKRLDISTPISMQLDXWPNDMQTCTFKFGS 541
++ + + + +P D+Q C KFGS
Sbjct: 138 CQYLPPGIFKSSCYIDVRWFPFDVQHCKLKFGS 170
>L08485-1|AAA58490.1| 462|Homo sapiens GABA-benzodiazepine receptor
alpha-5-subunit protein.
Length = 462
Score = 50.4 bits (115), Expect = 8e-06
Identities = 38/158 (24%), Positives = 69/158 (43%), Gaps = 7/158 (4%)
Frame = +2
Query: 113 ENATSLSLMIDSLLATYDRESPPD--SKIV-VNLTLHLRHAN-IRESESTVRILADLQMN 280
+N T + ++D LL YD P +I V +++ + ++E I + +
Sbjct: 44 DNITIFTRILDGLLDGYDNRLRPGLGERITQVRTDIYVTSFGPVSDTEMEYTIDVFFRQS 103
Query: 281 WIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSW 451
W D+RL + + + ++W PD N + A + R+ ++G++ +
Sbjct: 104 WKDERLRFKGPMQRLPLNNLLASKIWTPDTFFHNGKKSIAHNMTTPNKLLRLEDDGTLLY 163
Query: 452 IKRLDISTPISMQLDXWPNDMQTCTFKFGSRMXNSDEM 565
RL IS MQL+ +P D C KFGS + E+
Sbjct: 164 TMRLTISAECPMQLEDFPMDAHACPLKFGSYAYPNSEV 201
>BT009830-1|AAP88832.1| 462|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 5 protein.
Length = 462
Score = 50.4 bits (115), Expect = 8e-06
Identities = 38/158 (24%), Positives = 69/158 (43%), Gaps = 7/158 (4%)
Frame = +2
Query: 113 ENATSLSLMIDSLLATYDRESPPD--SKIV-VNLTLHLRHAN-IRESESTVRILADLQMN 280
+N T + ++D LL YD P +I V +++ + ++E I + +
Sbjct: 44 DNITIFTRILDGLLDGYDNRLRPGLGERITQVRTDIYVTSFGPVSDTEMEYTIDVFFRQS 103
Query: 281 WIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSW 451
W D+RL + + + ++W PD N + A + R+ ++G++ +
Sbjct: 104 WKDERLRFKGPMQRLPLNNLLASKIWTPDTFFHNGKKSIAHNMTTPNKLLRLEDDGTLLY 163
Query: 452 IKRLDISTPISMQLDXWPNDMQTCTFKFGSRMXNSDEM 565
RL IS MQL+ +P D C KFGS + E+
Sbjct: 164 TMRLTISAECPMQLEDFPMDAHACPLKFGSYAYPNSEV 201
>BC113422-1|AAI13423.1| 462|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 5 protein.
Length = 462
Score = 50.4 bits (115), Expect = 8e-06
Identities = 38/158 (24%), Positives = 69/158 (43%), Gaps = 7/158 (4%)
Frame = +2
Query: 113 ENATSLSLMIDSLLATYDRESPPD--SKIV-VNLTLHLRHAN-IRESESTVRILADLQMN 280
+N T + ++D LL YD P +I V +++ + ++E I + +
Sbjct: 44 DNITIFTRILDGLLDGYDNRLRPGLGERITQVRTDIYVTSFGPVSDTEMEYTIDVFFRQS 103
Query: 281 WIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSW 451
W D+RL + + + ++W PD N + A + R+ ++G++ +
Sbjct: 104 WKDERLRFKGPMQRLPLNNLLASKIWTPDTFFHNGKKSIAHNMTTPNKLLRLEDDGTLLY 163
Query: 452 IKRLDISTPISMQLDXWPNDMQTCTFKFGSRMXNSDEM 565
RL IS MQL+ +P D C KFGS + E+
Sbjct: 164 TMRLTISAECPMQLEDFPMDAHACPLKFGSYAYPNSEV 201
>BC111979-1|AAI11980.1| 462|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 5, precursor protein.
Length = 462
Score = 50.4 bits (115), Expect = 8e-06
Identities = 38/158 (24%), Positives = 69/158 (43%), Gaps = 7/158 (4%)
Frame = +2
Query: 113 ENATSLSLMIDSLLATYDRESPPD--SKIV-VNLTLHLRHAN-IRESESTVRILADLQMN 280
+N T + ++D LL YD P +I V +++ + ++E I + +
Sbjct: 44 DNITIFTRILDGLLDGYDNRLRPGLGERITQVRTDIYVTSFGPVSDTEMEYTIDVFFRQS 103
Query: 281 WIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSW 451
W D+RL + + + ++W PD N + A + R+ ++G++ +
Sbjct: 104 WKDERLRFKGPMQRLPLNNLLASKIWTPDTFFHNGKKSIAHNMTTPNKLLRLEDDGTLLY 163
Query: 452 IKRLDISTPISMQLDXWPNDMQTCTFKFGSRMXNSDEM 565
RL IS MQL+ +P D C KFGS + E+
Sbjct: 164 TMRLTISAECPMQLEDFPMDAHACPLKFGSYAYPNSEV 201
>AF385585-1|AAK68111.1| 502|Homo sapiens nicotinic cholinergic
receptor alpha 7 protein.
Length = 502
Score = 50.4 bits (115), Expect = 8e-06
Identities = 27/93 (29%), Positives = 45/93 (48%), Gaps = 2/93 (2%)
Frame = +2
Query: 269 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSNNGS 442
LQM+W D L WN E+ G T ++W+PD++L N+A + V+ +G
Sbjct: 78 LQMSWTDHYLQWNVSEYPGVKTVRFPDGQIWKPDILLYNSADERFDATFHTNVLVNPSGH 137
Query: 443 VSWIKRLDISTPISMQLDXWPNDMQTCTFKFGS 541
++ + + + +P D+Q C KFGS
Sbjct: 138 CQYLPPGIFKSSCYIDVRWFPFDVQHCKLKFGS 170
>AK122638-1|BAC85499.1| 266|Homo sapiens yte protein of 76kDa)
(LCP2). protein.
Length = 266
Score = 50.0 bits (114), Expect = 1e-05
Identities = 26/89 (29%), Positives = 41/89 (46%)
Frame = +2
Query: 269 LQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVS 448
L+++W+D RL+WN + E LW P + +L A D + +ARV +G V
Sbjct: 87 LRLSWLDTRLAWNTSAHPRHAITLPWESLWTPRLTILEALWVDWRDQSPQARVDQDGHVK 146
Query: 449 WIKRLDISTPISMQLDXWPNDMQTCTFKF 535
L T + +L +P D C+ F
Sbjct: 147 LNLALTTETNCNFELLHFPRDHSNCSLSF 175
>BC028629-1|AAH28629.1| 492|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 3 protein.
Length = 492
Score = 49.2 bits (112), Expect = 2e-05
Identities = 36/158 (22%), Positives = 68/158 (43%), Gaps = 7/158 (4%)
Frame = +2
Query: 113 ENATSLSLMIDSLLATYDRESPP---DSKIVVNLTLHLRHAN-IRESESTVRILADLQMN 280
+N T + ++D LL YD P D+ V +++ + +++ I +
Sbjct: 62 DNITIFTRILDRLLDGYDNRLRPGLGDAVTEVKTDIYVTSFGPVSDTDMEYTIDVFFRQT 121
Query: 281 WIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSW 451
W D+RL ++ + + ++W PD N + A + R+ +NG++ +
Sbjct: 122 WHDERLKFDGPMKILPLNNLLASKIWTPDTFFHNGKKSVAHNMTTPNKLLRLVDNGTLPY 181
Query: 452 IKRLDISTPISMQLDXWPNDMQTCTFKFGSRMXNSDEM 565
RL I M L+ +P D+ C KFGS + E+
Sbjct: 182 TMRLTIHAECPMHLEDFPMDVHACPLKFGSYAYTTAEV 219
>S62908-1|AAB27279.1| 492|Homo sapiens gamma-aminobutyric acidA
receptor alpha 3 subunit protein.
Length = 492
Score = 48.8 bits (111), Expect = 2e-05
Identities = 36/158 (22%), Positives = 68/158 (43%), Gaps = 7/158 (4%)
Frame = +2
Query: 113 ENATSLSLMIDSLLATYDRESPP---DSKIVVNLTLHLRHAN-IRESESTVRILADLQMN 280
+N T + ++D LL YD P D+ V +++ + +++ I +
Sbjct: 62 DNITIFTRILDRLLDGYDNRLRPGLGDAVTEVKTDIYVTSFGPVSDTDMEYTIDVFFRQT 121
Query: 281 WIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSW 451
W D+RL ++ + + ++W PD N + A + R+ +NG++ +
Sbjct: 122 WHDERLKFDGPMKILPLNNLLASKIWTPDTFFHNGKKSVAHNMTTPNKLLRLVDNGTLLY 181
Query: 452 IKRLDISTPISMQLDXWPNDMQTCTFKFGSRMXNSDEM 565
RL I M L+ +P D+ C KFGS + E+
Sbjct: 182 TMRLTIHAECPMHLEDFPMDVHACPLKFGSYAYTTAEV 219
>AF166361-1|AAG12455.1| 492|Homo sapiens GABA receptor subunit
alpha 3 protein.
Length = 492
Score = 48.8 bits (111), Expect = 2e-05
Identities = 36/158 (22%), Positives = 68/158 (43%), Gaps = 7/158 (4%)
Frame = +2
Query: 113 ENATSLSLMIDSLLATYDRESPP---DSKIVVNLTLHLRHAN-IRESESTVRILADLQMN 280
+N T + ++D LL YD P D+ V +++ + +++ I +
Sbjct: 62 DNITIFTRILDRLLDGYDNRLRPGLGDAVTEVKTDIYVTSFGPVSDTDMEYTIDVFFRQT 121
Query: 281 WIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSW 451
W D+RL ++ + + ++W PD N + A + R+ +NG++ +
Sbjct: 122 WHDERLKFDGPMKILPLNNLLASKIWTPDTFFHNGKKSVAHNMTTPNKLLRLVDNGTLLY 181
Query: 452 IKRLDISTPISMQLDXWPNDMQTCTFKFGSRMXNSDEM 565
RL I M L+ +P D+ C KFGS + E+
Sbjct: 182 TMRLTIHAECPMHLEDFPMDVHACPLKFGSYAYTTAEV 219
>BC022449-1|AAH22449.1| 474|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, beta 1 protein.
Length = 474
Score = 46.8 bits (106), Expect = 1e-04
Identities = 39/171 (22%), Positives = 72/171 (42%), Gaps = 7/171 (4%)
Frame = +2
Query: 80 LTCAIASAAECENATSLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESES 247
+ C S E N + + +D LL YD PD + V + + + + + E
Sbjct: 21 MVCCAHSTNEPSNMSYVKETVDRLLKGYDIRLRPDFGGPPVDVGMRIDVASIDMVSEVNM 80
Query: 248 TVRILADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR--- 418
+ Q +W DKRLS++ + +++L PD LN + ++
Sbjct: 81 DYTLTMYFQQSWKDKRLSYSGIPLNLTLDNRVADQLCVPDTYFLNDKKSFVHGVTVKNRM 140
Query: 419 ARVSNNGSVSWIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMXNSDEMDF 571
R+ +G+V + R+ + M L +P D Q CT + S +D+++F
Sbjct: 141 IRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEF 191
>BC109211-1|AAI09212.1| 632|Homo sapiens gamma-aminobutyric acid
(GABA) receptor, theta protein.
Length = 632
Score = 46.4 bits (105), Expect = 1e-04
Identities = 35/145 (24%), Positives = 60/145 (41%), Gaps = 7/145 (4%)
Frame = +2
Query: 110 CENATSLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESESTVRILADLQM 277
C N + ++D +L+ YD P+ + + V +++++ I E I
Sbjct: 53 CANEAVVQKILDRVLSRYDVRLRPNFGGAPVPVRISIYVTSIEQISEMNMDYTITMFFHQ 112
Query: 278 NWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSN---NGSVS 448
W D RL++ + E+LW PD LN+ D + RV +G+V
Sbjct: 113 TWKDSRLAYYETTLNLTLDYRMHEKLWVPDCYFLNSKDAFVHDVTVENRVFQLHPDGTVR 172
Query: 449 WIKRLDISTPISMQLDXWPNDMQTC 523
+ RL + S+ L +P D Q C
Sbjct: 173 YGIRLTTTAACSLDLHKFPMDKQAC 197
>BC109210-1|AAI09211.1| 632|Homo sapiens gamma-aminobutyric acid
(GABA) receptor, theta protein.
Length = 632
Score = 46.4 bits (105), Expect = 1e-04
Identities = 35/145 (24%), Positives = 60/145 (41%), Gaps = 7/145 (4%)
Frame = +2
Query: 110 CENATSLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESESTVRILADLQM 277
C N + ++D +L+ YD P+ + + V +++++ I E I
Sbjct: 53 CANEAVVQKILDRVLSRYDVRLRPNFGGAPVPVRISIYVTSIEQISEMNMDYTITMFFHQ 112
Query: 278 NWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSN---NGSVS 448
W D RL++ + E+LW PD LN+ D + RV +G+V
Sbjct: 113 TWKDSRLAYYETTLNLTLDYRMHEKLWVPDCYFLNSKDAFVHDVTVENRVFQLHPDGTVR 172
Query: 449 WIKRLDISTPISMQLDXWPNDMQTC 523
+ RL + S+ L +P D Q C
Sbjct: 173 YGIRLTTTAACSLDLHKFPMDKQAC 197
>BC096083-1|AAH96083.1| 198|Homo sapiens CHRNB4 protein protein.
Length = 198
Score = 46.4 bits (105), Expect = 1e-04
Identities = 30/115 (26%), Positives = 54/115 (46%), Gaps = 8/115 (6%)
Frame = +2
Query: 89 AIASAAECENATSLSLMIDSLL--ATYDRESPP--DSKIVVNLTLHLRHA---NIRESES 247
A+ C A + ++D LL Y+ P S ++++ L L A ++ E E
Sbjct: 14 ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQ 73
Query: 248 TVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDY 409
+ L+ W D RL+WN+ + G + + ++R+W PD+VL N + T +
Sbjct: 74 IMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNKSLRTGSTW 128
>BC096081-1|AAH96081.1| 198|Homo sapiens CHRNB4 protein protein.
Length = 198
Score = 46.4 bits (105), Expect = 1e-04
Identities = 30/115 (26%), Positives = 54/115 (46%), Gaps = 8/115 (6%)
Frame = +2
Query: 89 AIASAAECENATSLSLMIDSLL--ATYDRESPP--DSKIVVNLTLHLRHA---NIRESES 247
A+ C A + ++D LL Y+ P S ++++ L L A ++ E E
Sbjct: 14 ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQ 73
Query: 248 TVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDY 409
+ L+ W D RL+WN+ + G + + ++R+W PD+VL N + T +
Sbjct: 74 IMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNKSLRTGSTW 128
>AF189259-1|AAF70380.1| 632|Homo sapiens GABA-A receptor theta
subunit protein.
Length = 632
Score = 46.4 bits (105), Expect = 1e-04
Identities = 35/145 (24%), Positives = 60/145 (41%), Gaps = 7/145 (4%)
Frame = +2
Query: 110 CENATSLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESESTVRILADLQM 277
C N + ++D +L+ YD P+ + + V +++++ I E I
Sbjct: 53 CANEAVVQKILDRVLSRYDVRLRPNFGGAPVPVRISIYVTSIEQISEMNMDYTITMFFHQ 112
Query: 278 NWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSN---NGSVS 448
W D RL++ + E+LW PD LN+ D + RV +G+V
Sbjct: 113 TWKDSRLAYYETTLNLTLDYRMHEKLWVPDCYFLNSKDAFVHDVTVENRVFQLHPDGTVR 172
Query: 449 WIKRLDISTPISMQLDXWPNDMQTC 523
+ RL + S+ L +P D Q C
Sbjct: 173 YGIRLTTTAACSLDLHKFPMDKQAC 197
>AF144648-1|AAD51172.1| 627|Homo sapiens GABA-A receptor theta
protein.
Length = 627
Score = 46.4 bits (105), Expect = 1e-04
Identities = 35/145 (24%), Positives = 60/145 (41%), Gaps = 7/145 (4%)
Frame = +2
Query: 110 CENATSLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESESTVRILADLQM 277
C N + ++D +L+ YD P+ + + V +++++ I E I
Sbjct: 48 CANEAVVQKILDRVLSRYDVRLRPNFGGAPVPVRISIYVTSIEQISEMNMDYTITMFFHQ 107
Query: 278 NWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSN---NGSVS 448
W D RL++ + E+LW PD LN+ D + RV +G+V
Sbjct: 108 TWKDSRLAYYETTLNLTLDYRMHEKLWVPDCYFLNSKDAFVHDVTVENRVFQLHPDGTVR 167
Query: 449 WIKRLDISTPISMQLDXWPNDMQTC 523
+ RL + S+ L +P D Q C
Sbjct: 168 YGIRLTTTAACSLDLHKFPMDKQAC 192
>U77731-2|AAB38273.1| 360|Homo sapiens glycine receptor alpha 2B
subunit protein.
Length = 360
Score = 46.0 bits (104), Expect = 2e-04
Identities = 37/135 (27%), Positives = 59/135 (43%), Gaps = 8/135 (5%)
Frame = +2
Query: 161 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 328
YD P+ K VN+T ++ +I E+ R+ L+ W D RL+++
Sbjct: 58 YDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDSRLAYSEYPDDSL 117
Query: 329 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLD 496
S + +W+PD+ N D R+S NG V + RL ++ M L
Sbjct: 118 DLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLK 177
Query: 497 XWPNDMQTCTFKFGS 541
+P D+QTCT + S
Sbjct: 178 NFPMDVQTCTMQLES 192
>U30461-1|AAB52519.1| 554|Homo sapiens GABAA receptor subunit
alpha4 protein.
Length = 554
Score = 46.0 bits (104), Expect = 2e-04
Identities = 31/113 (27%), Positives = 48/113 (42%), Gaps = 3/113 (2%)
Frame = +2
Query: 236 ESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYAL 415
E E T+ + + WIDKRL ++ + ++W PD N + + +
Sbjct: 90 EMEYTMDVF--FRQTWIDKRLKYDGPIEILRLNNMMVTKVWTPDTFFRNGKKSVSHNMTA 147
Query: 416 RA---RVSNNGSVSWIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMXNSDEM 565
R+ NG++ + RL IS M+L +P D C KFGS EM
Sbjct: 148 PNKLFRIMRNGTILYTMRLTISAECPMRLVDFPMDGHACPLKFGSYAYPKSEM 200
>CR450343-1|CAG29339.1| 452|Homo sapiens GLRA2 protein.
Length = 452
Score = 46.0 bits (104), Expect = 2e-04
Identities = 37/135 (27%), Positives = 59/135 (43%), Gaps = 8/135 (5%)
Frame = +2
Query: 161 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 328
YD P+ K VN+T ++ +I E+ R+ L+ W D RL+++
Sbjct: 58 YDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDSRLAYSEYPDDSL 117
Query: 329 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLD 496
S + +W+PD+ N D R+S NG V + RL ++ M L
Sbjct: 118 DLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLK 177
Query: 497 XWPNDMQTCTFKFGS 541
+P D+QTCT + S
Sbjct: 178 NFPMDVQTCTMQLES 192
>BC035055-1|AAH35055.1| 554|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 4 protein.
Length = 554
Score = 46.0 bits (104), Expect = 2e-04
Identities = 31/113 (27%), Positives = 48/113 (42%), Gaps = 3/113 (2%)
Frame = +2
Query: 236 ESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYAL 415
E E T+ + + WIDKRL ++ + ++W PD N + + +
Sbjct: 90 EMEYTMDVF--FRQTWIDKRLKYDGPIEILRLNNMMVTKVWTPDTFFRNGKKSVSHNMTA 147
Query: 416 RA---RVSNNGSVSWIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMXNSDEM 565
R+ NG++ + RL IS M+L +P D C KFGS EM
Sbjct: 148 PNKLFRIMRNGTILYTMRLTISAECPMRLVDFPMDGHACPLKFGSYAYPKSEM 200
>AY437084-1|AAR87843.1| 452|Homo sapiens glycine receptor alpha2
subunit B protein.
Length = 452
Score = 46.0 bits (104), Expect = 2e-04
Identities = 37/135 (27%), Positives = 59/135 (43%), Gaps = 8/135 (5%)
Frame = +2
Query: 161 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 328
YD P+ K VN+T ++ +I E+ R+ L+ W D RL+++
Sbjct: 58 YDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDSRLAYSEYPDDSL 117
Query: 329 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLD 496
S + +W+PD+ N D R+S NG V + RL ++ M L
Sbjct: 118 DLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLK 177
Query: 497 XWPNDMQTCTFKFGS 541
+P D+QTCT + S
Sbjct: 178 NFPMDVQTCTMQLES 192
>X52008-1|CAA36257.1| 452|Homo sapiens inhibitory glycine receptor
protein.
Length = 452
Score = 45.6 bits (103), Expect = 2e-04
Identities = 36/135 (26%), Positives = 59/135 (43%), Gaps = 8/135 (5%)
Frame = +2
Query: 161 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 328
YD P+ K VN+T ++ ++ E+ R+ L+ W D RL+++
Sbjct: 58 YDARIRPNFKGPPVNVTCNIFINSFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPDDSL 117
Query: 329 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLD 496
S + +W+PD+ N D R+S NG V + RL ++ M L
Sbjct: 118 DLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLK 177
Query: 497 XWPNDMQTCTFKFGS 541
+P D+QTCT + S
Sbjct: 178 NFPMDVQTCTMQLES 192
>U77731-1|AAB38272.1| 360|Homo sapiens glycine receptor alpha 2
subunit protein.
Length = 360
Score = 45.6 bits (103), Expect = 2e-04
Identities = 36/135 (26%), Positives = 59/135 (43%), Gaps = 8/135 (5%)
Frame = +2
Query: 161 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 328
YD P+ K VN+T ++ ++ E+ R+ L+ W D RL+++
Sbjct: 58 YDARIRPNFKGPPVNVTCNIFINSFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPDDSL 117
Query: 329 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLD 496
S + +W+PD+ N D R+S NG V + RL ++ M L
Sbjct: 118 DLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLK 177
Query: 497 XWPNDMQTCTFKFGS 541
+P D+QTCT + S
Sbjct: 178 NFPMDVQTCTMQLES 192
>BC032864-1|AAH32864.1| 452|Homo sapiens glycine receptor, alpha 2
protein.
Length = 452
Score = 45.6 bits (103), Expect = 2e-04
Identities = 36/135 (26%), Positives = 59/135 (43%), Gaps = 8/135 (5%)
Frame = +2
Query: 161 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 328
YD P+ K VN+T ++ ++ E+ R+ L+ W D RL+++
Sbjct: 58 YDARIRPNFKGPPVNVTCNIFINSFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPDDSL 117
Query: 329 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLD 496
S + +W+PD+ N D R+S NG V + RL ++ M L
Sbjct: 118 DLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLK 177
Query: 497 XWPNDMQTCTFKFGS 541
+P D+QTCT + S
Sbjct: 178 NFPMDVQTCTMQLES 192
>AY437083-1|AAR87842.1| 452|Homo sapiens glycine receptor alpha2
subunit A protein.
Length = 452
Score = 45.6 bits (103), Expect = 2e-04
Identities = 36/135 (26%), Positives = 59/135 (43%), Gaps = 8/135 (5%)
Frame = +2
Query: 161 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 328
YD P+ K VN+T ++ ++ E+ R+ L+ W D RL+++
Sbjct: 58 YDARIRPNFKGPPVNVTCNIFINSFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPDDSL 117
Query: 329 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLD 496
S + +W+PD+ N D R+S NG V + RL ++ M L
Sbjct: 118 DLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLK 177
Query: 497 XWPNDMQTCTFKFGS 541
+P D+QTCT + S
Sbjct: 178 NFPMDVQTCTMQLES 192
>AF053495-1|AAC35290.1| 452|Homo sapiens glycine receptor alpha 2
subunit protein.
Length = 452
Score = 45.6 bits (103), Expect = 2e-04
Identities = 36/135 (26%), Positives = 59/135 (43%), Gaps = 8/135 (5%)
Frame = +2
Query: 161 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 328
YD P+ K VN+T ++ ++ E+ R+ L+ W D RL+++
Sbjct: 58 YDARIRPNFKGPPVNVTCNIFINSFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPDDSL 117
Query: 329 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLD 496
S + +W+PD+ N D R+S NG V + RL ++ M L
Sbjct: 118 DLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLK 177
Query: 497 XWPNDMQTCTFKFGS 541
+P D+QTCT + S
Sbjct: 178 NFPMDVQTCTMQLES 192
>U95367-1|AAC51357.1| 440|Homo sapiens GABA-A receptor pi subunit
protein.
Length = 440
Score = 45.2 bits (102), Expect = 3e-04
Identities = 40/164 (24%), Positives = 77/164 (46%), Gaps = 9/164 (5%)
Frame = +2
Query: 107 ECENATSLSLM-IDSLLATYDRESPPD---SKIVVNLTLHLRH-ANIRESESTVRILADL 271
E + LSL ++L A Y++ P+ + + LTL + ++I ES L
Sbjct: 29 EVGRSDKLSLPGFENLTAGYNKFLRPNFGGEPVQIALTLDIASISSISESNMDYTATIYL 88
Query: 272 QMNWIDKRLSWNAGE-WGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNG 439
+ W+D+RL + + + LV E LW PD ++ + + + + R+ +NG
Sbjct: 89 RQRWMDQRLVFEGNKSFTLDARLV--EFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNG 146
Query: 440 SVSWIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMXNSDEMDF 571
+V + R+ + +M L +P D QTC + S + ++++F
Sbjct: 147 TVLYALRITTTVACNMDLSKYPMDTQTCKLQLESWGYDGNDVEF 190
>BC109106-1|AAI09107.1| 440|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, pi protein.
Length = 440
Score = 45.2 bits (102), Expect = 3e-04
Identities = 40/164 (24%), Positives = 77/164 (46%), Gaps = 9/164 (5%)
Frame = +2
Query: 107 ECENATSLSLM-IDSLLATYDRESPPD---SKIVVNLTLHLRH-ANIRESESTVRILADL 271
E + LSL ++L A Y++ P+ + + LTL + ++I ES L
Sbjct: 29 EVGRSDKLSLPGFENLTAGYNKFLRPNFGGEPVQIALTLDIASISSISESNMDYTATIYL 88
Query: 272 QMNWIDKRLSWNAGE-WGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNG 439
+ W+D+RL + + + LV E LW PD ++ + + + + R+ +NG
Sbjct: 89 RQRWMDQRLVFEGNKSFTLDARLV--EFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNG 146
Query: 440 SVSWIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMXNSDEMDF 571
+V + R+ + +M L +P D QTC + S + ++++F
Sbjct: 147 TVLYALRITTTVACNMDLSKYPMDTQTCKLQLESWGYDGNDVEF 190
>BC109105-1|AAI09106.1| 440|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, pi protein.
Length = 440
Score = 45.2 bits (102), Expect = 3e-04
Identities = 40/164 (24%), Positives = 77/164 (46%), Gaps = 9/164 (5%)
Frame = +2
Query: 107 ECENATSLSLM-IDSLLATYDRESPPD---SKIVVNLTLHLRH-ANIRESESTVRILADL 271
E + LSL ++L A Y++ P+ + + LTL + ++I ES L
Sbjct: 29 EVGRSDKLSLPGFENLTAGYNKFLRPNFGGEPVQIALTLDIASISSISESNMDYTATIYL 88
Query: 272 QMNWIDKRLSWNAGE-WGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNG 439
+ W+D+RL + + + LV E LW PD ++ + + + + R+ +NG
Sbjct: 89 RQRWMDQRLVFEGNKSFTLDARLV--EFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNG 146
Query: 440 SVSWIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMXNSDEMDF 571
+V + R+ + +M L +P D QTC + S + ++++F
Sbjct: 147 TVLYALRITTTVACNMDLSKYPMDTQTCKLQLESWGYDGNDVEF 190
>BC074865-1|AAH74865.1| 440|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, pi protein.
Length = 440
Score = 45.2 bits (102), Expect = 3e-04
Identities = 40/164 (24%), Positives = 77/164 (46%), Gaps = 9/164 (5%)
Frame = +2
Query: 107 ECENATSLSLM-IDSLLATYDRESPPD---SKIVVNLTLHLRH-ANIRESESTVRILADL 271
E + LSL ++L A Y++ P+ + + LTL + ++I ES L
Sbjct: 29 EVGRSDKLSLPGFENLTAGYNKFLRPNFGGEPVQIALTLDIASISSISESNMDYTATIYL 88
Query: 272 QMNWIDKRLSWNAGE-WGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNG 439
+ W+D+RL + + + LV E LW PD ++ + + + + R+ +NG
Sbjct: 89 RQRWMDQRLVFEGNKSFTLDARLV--EFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNG 146
Query: 440 SVSWIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMXNSDEMDF 571
+V + R+ + +M L +P D QTC + S + ++++F
Sbjct: 147 TVLYALRITTTVACNMDLSKYPMDTQTCKLQLESWGYDGNDVEF 190
>BC074810-1|AAH74810.1| 440|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, pi protein.
Length = 440
Score = 45.2 bits (102), Expect = 3e-04
Identities = 40/164 (24%), Positives = 77/164 (46%), Gaps = 9/164 (5%)
Frame = +2
Query: 107 ECENATSLSLM-IDSLLATYDRESPPD---SKIVVNLTLHLRH-ANIRESESTVRILADL 271
E + LSL ++L A Y++ P+ + + LTL + ++I ES L
Sbjct: 29 EVGRSDKLSLPGFENLTAGYNKFLRPNFGGEPVQIALTLDIASISSISESNMDYTATIYL 88
Query: 272 QMNWIDKRLSWNAGE-WGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNG 439
+ W+D+RL + + + LV E LW PD ++ + + + + R+ +NG
Sbjct: 89 RQRWMDQRLVFEGNKSFTLDARLV--EFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNG 146
Query: 440 SVSWIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMXNSDEMDF 571
+V + R+ + +M L +P D QTC + S + ++++F
Sbjct: 147 TVLYALRITTTVACNMDLSKYPMDTQTCKLQLESWGYDGNDVEF 190
>BC033801-1|AAH33801.1| 452|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, delta protein.
Length = 452
Score = 45.2 bits (102), Expect = 3e-04
Identities = 38/149 (25%), Positives = 63/149 (42%), Gaps = 7/149 (4%)
Frame = +2
Query: 140 IDSLLATYDRESPPD-SKIVVNLTLHLRHANI---RESESTVRILADLQMNWIDKRLSWN 307
+D L+A Y R P VN+ L L A+I E+ + L +W D RLS+N
Sbjct: 44 LDGLIAGYARNFRPGIGGPPVNVALALEVASIDHISEANMEYTMTVFLHQSWRDSRLSYN 103
Query: 308 AGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTP 478
++LW PD ++NA + D + R+ +G + + R+ +
Sbjct: 104 HTNETLGLDSRFVDKLWLPDTFIVNAKSAWFHDVTVENKLIRLQPDGVILYSIRITSTVA 163
Query: 479 ISMQLDXWPNDMQTCTFKFGSRMXNSDEM 565
M L +P D Q C S +S+++
Sbjct: 164 CDMDLAKYPMDEQECMLDLESYGYSSEDI 192
>AL391845-4|CAI15436.1| 452|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, delta protein.
Length = 452
Score = 45.2 bits (102), Expect = 3e-04
Identities = 38/149 (25%), Positives = 63/149 (42%), Gaps = 7/149 (4%)
Frame = +2
Query: 140 IDSLLATYDRESPPD-SKIVVNLTLHLRHANI---RESESTVRILADLQMNWIDKRLSWN 307
+D L+A Y R P VN+ L L A+I E+ + L +W D RLS+N
Sbjct: 44 LDGLIAGYARNFRPGIGGPPVNVALALEVASIDHISEANMEYTMTVFLHQSWRDSRLSYN 103
Query: 308 AGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTP 478
++LW PD ++NA + D + R+ +G + + R+ +
Sbjct: 104 HTNETLGLDSRFVDKLWLPDTFIVNAKSAWFHDVTVENKLIRLQPDGVILYSIRITSTVA 163
Query: 479 ISMQLDXWPNDMQTCTFKFGSRMXNSDEM 565
M L +P D Q C S +S+++
Sbjct: 164 CDMDLAKYPMDEQECMLDLESYGYSSEDI 192
>AF016917-1|AAB70007.1| 452|Homo sapiens GABA-A receptor delta
subunit protein.
Length = 452
Score = 45.2 bits (102), Expect = 3e-04
Identities = 38/149 (25%), Positives = 63/149 (42%), Gaps = 7/149 (4%)
Frame = +2
Query: 140 IDSLLATYDRESPPD-SKIVVNLTLHLRHANI---RESESTVRILADLQMNWIDKRLSWN 307
+D L+A Y R P VN+ L L A+I E+ + L +W D RLS+N
Sbjct: 44 LDGLIAGYARNFRPGIGGPPVNVALALEVASIDHISEANMEYTMTVFLHQSWRDSRLSYN 103
Query: 308 AGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTP 478
++LW PD ++NA + D + R+ +G + + R+ +
Sbjct: 104 HTNETLGLDSRFVDKLWLPDTFIVNAKSAWFHDVTVENKLIRLQPDGVILYSIRITSTVA 163
Query: 479 ISMQLDXWPNDMQTCTFKFGSRMXNSDEM 565
M L +P D Q C S +S+++
Sbjct: 164 CDMDLAKYPMDEQECMLDLESYGYSSEDI 192
>AF009702-1|AAC24194.1| 440|Homo sapiens GABA-A receptor pi subunit
protein.
Length = 440
Score = 45.2 bits (102), Expect = 3e-04
Identities = 40/164 (24%), Positives = 77/164 (46%), Gaps = 9/164 (5%)
Frame = +2
Query: 107 ECENATSLSLM-IDSLLATYDRESPPD---SKIVVNLTLHLRH-ANIRESESTVRILADL 271
E + LSL ++L A Y++ P+ + + LTL + ++I ES L
Sbjct: 29 EVGRSDKLSLPGFENLTAGYNKFLRPNFGGEPVQIALTLDIASISSISESNMDYTATIYL 88
Query: 272 QMNWIDKRLSWNAGE-WGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNG 439
+ W+D+RL + + + LV E LW PD ++ + + + + R+ +NG
Sbjct: 89 RQRWMDQRLVFEGNKSFTLDARLV--EFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNG 146
Query: 440 SVSWIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMXNSDEMDF 571
+V + R+ + +M L +P D QTC + S + ++++F
Sbjct: 147 TVLYALRITTTVACNMDLSKYPMDTQTCKLQLESWGYDGNDVEF 190
>S81944-1|AAB36480.1| 453|Homo sapiens gamma-aminobutyric acid type
A receptor alpha 6 subunit protein.
Length = 453
Score = 44.4 bits (100), Expect = 5e-04
Identities = 34/146 (23%), Positives = 61/146 (41%), Gaps = 7/146 (4%)
Frame = +2
Query: 125 SLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESESTVRILADLQMNWIDK 292
++S ++D+LL YD P + V +++ + + E + + W D+
Sbjct: 31 NVSRILDNLLEGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTDE 90
Query: 293 RLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRA---RVSNNGSVSWIKRL 463
RL + S + ++W PD N + A + R+ NG++ + RL
Sbjct: 91 RLKFGGPTEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTMRL 150
Query: 464 DISTPISMQLDXWPNDMQTCTFKFGS 541
I+ M+L +P D C KFGS
Sbjct: 151 TINADCPMRLVNFPMDGHACPLKFGS 176
>BC099641-1|AAH99641.1| 453|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 6 protein.
Length = 453
Score = 44.4 bits (100), Expect = 5e-04
Identities = 34/146 (23%), Positives = 61/146 (41%), Gaps = 7/146 (4%)
Frame = +2
Query: 125 SLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESESTVRILADLQMNWIDK 292
++S ++D+LL YD P + V +++ + + E + + W D+
Sbjct: 31 NVSRILDNLLEGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTDE 90
Query: 293 RLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRA---RVSNNGSVSWIKRL 463
RL + S + ++W PD N + A + R+ NG++ + RL
Sbjct: 91 RLKFGGPTEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTMRL 150
Query: 464 DISTPISMQLDXWPNDMQTCTFKFGS 541
I+ M+L +P D C KFGS
Sbjct: 151 TINADCPMRLVNFPMDGHACPLKFGS 176
>BC099640-1|AAH99640.1| 453|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 6 protein.
Length = 453
Score = 44.4 bits (100), Expect = 5e-04
Identities = 34/146 (23%), Positives = 61/146 (41%), Gaps = 7/146 (4%)
Frame = +2
Query: 125 SLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESESTVRILADLQMNWIDK 292
++S ++D+LL YD P + V +++ + + E + + W D+
Sbjct: 31 NVSRILDNLLEGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTDE 90
Query: 293 RLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRA---RVSNNGSVSWIKRL 463
RL + S + ++W PD N + A + R+ NG++ + RL
Sbjct: 91 RLKFGGPTEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTMRL 150
Query: 464 DISTPISMQLDXWPNDMQTCTFKFGS 541
I+ M+L +P D C KFGS
Sbjct: 151 TINADCPMRLVNFPMDGHACPLKFGS 176
>BC096242-1|AAH96242.1| 453|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 6 protein.
Length = 453
Score = 44.4 bits (100), Expect = 5e-04
Identities = 34/146 (23%), Positives = 61/146 (41%), Gaps = 7/146 (4%)
Frame = +2
Query: 125 SLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESESTVRILADLQMNWIDK 292
++S ++D+LL YD P + V +++ + + E + + W D+
Sbjct: 31 NVSRILDNLLEGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTDE 90
Query: 293 RLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRA---RVSNNGSVSWIKRL 463
RL + S + ++W PD N + A + R+ NG++ + RL
Sbjct: 91 RLKFGGPTEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTMRL 150
Query: 464 DISTPISMQLDXWPNDMQTCTFKFGS 541
I+ M+L +P D C KFGS
Sbjct: 151 TINADCPMRLVNFPMDGHACPLKFGS 176
>BC096241-1|AAH96241.1| 453|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 6 protein.
Length = 453
Score = 44.4 bits (100), Expect = 5e-04
Identities = 34/146 (23%), Positives = 61/146 (41%), Gaps = 7/146 (4%)
Frame = +2
Query: 125 SLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESESTVRILADLQMNWIDK 292
++S ++D+LL YD P + V +++ + + E + + W D+
Sbjct: 31 NVSRILDNLLEGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTDE 90
Query: 293 RLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRA---RVSNNGSVSWIKRL 463
RL + S + ++W PD N + A + R+ NG++ + RL
Sbjct: 91 RLKFGGPTEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTMRL 150
Query: 464 DISTPISMQLDXWPNDMQTCTFKFGS 541
I+ M+L +P D C KFGS
Sbjct: 151 TINADCPMRLVNFPMDGHACPLKFGS 176
>X52009-1|CAA36258.1| 449|Homo sapiens inhibitory glycine receptor
protein.
Length = 449
Score = 40.7 bits (91), Expect = 0.007
Identities = 28/109 (25%), Positives = 48/109 (44%), Gaps = 4/109 (3%)
Frame = +2
Query: 227 NIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERLWRPDVVLLNAAATTAG 403
+I E+ R+ L+ W D RL++N S + +W+PD+ N
Sbjct: 78 SIAETTMDYRVNIFLRQQWNDPRLAYNEYPDDSLDLDPSMLDSIWKPDLFFANEKGAHFH 137
Query: 404 DYALR---ARVSNNGSVSWIKRLDISTPISMQLDXWPNDMQTCTFKFGS 541
+ R+S NG+V + R+ ++ M L +P D+QTC + S
Sbjct: 138 EITTDNKLLRISRNGNVLYSIRITLTLACPMDLKNFPMDVQTCIMQLES 186
>BC114947-1|AAI14948.1| 457|Homo sapiens GLRA1 protein protein.
Length = 457
Score = 40.7 bits (91), Expect = 0.007
Identities = 28/109 (25%), Positives = 48/109 (44%), Gaps = 4/109 (3%)
Frame = +2
Query: 227 NIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERLWRPDVVLLNAAATTAG 403
+I E+ R+ L+ W D RL++N S + +W+PD+ N
Sbjct: 78 SIAETTMDYRVNIFLRQQWNDPRLAYNEYPDDSLDLDPSMLDSIWKPDLFFANEKGAHFH 137
Query: 404 DYALR---ARVSNNGSVSWIKRLDISTPISMQLDXWPNDMQTCTFKFGS 541
+ R+S NG+V + R+ ++ M L +P D+QTC + S
Sbjct: 138 EITTDNKLLRISRNGNVLYSIRITLTLACPMDLKNFPMDVQTCIMQLES 186
>BC074980-1|AAH74980.1| 449|Homo sapiens glycine receptor, alpha 1
(startle disease/hyperekplexia) protein.
Length = 449
Score = 40.7 bits (91), Expect = 0.007
Identities = 28/109 (25%), Positives = 48/109 (44%), Gaps = 4/109 (3%)
Frame = +2
Query: 227 NIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERLWRPDVVLLNAAATTAG 403
+I E+ R+ L+ W D RL++N S + +W+PD+ N
Sbjct: 78 SIAETTMDYRVNIFLRQQWNDPRLAYNEYPDDSLDLDPSMLDSIWKPDLFFANEKGAHFH 137
Query: 404 DYALR---ARVSNNGSVSWIKRLDISTPISMQLDXWPNDMQTCTFKFGS 541
+ R+S NG+V + R+ ++ M L +P D+QTC + S
Sbjct: 138 EITTDNKLLRISRNGNVLYSIRITLTLACPMDLKNFPMDVQTCIMQLES 186
>Z93848-1|CAI41994.1| 376|Homo sapiens glycine receptor, alpha 4
protein.
Length = 376
Score = 40.3 bits (90), Expect = 0.009
Identities = 35/135 (25%), Positives = 58/135 (42%), Gaps = 8/135 (5%)
Frame = +2
Query: 161 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 328
YD P+ K VN+T ++ ++I ++ R+ L+ W D RLS+
Sbjct: 17 YDARIRPNFKGPPVNVTCNIFINSFSSITKTTMDYRVNVFLRQQWNDPRLSYREYPDDSL 76
Query: 329 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLD 496
S + +W+PD+ N + R+ NG+V + RL + M L
Sbjct: 77 DLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLILSCLMDLK 136
Query: 497 XWPNDMQTCTFKFGS 541
+P D+QTCT + S
Sbjct: 137 NFPMDIQTCTMQLES 151
>AL049610-1|CAI42158.1| 376|Homo sapiens glycine receptor, alpha 4
protein.
Length = 376
Score = 40.3 bits (90), Expect = 0.009
Identities = 35/135 (25%), Positives = 58/135 (42%), Gaps = 8/135 (5%)
Frame = +2
Query: 161 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 328
YD P+ K VN+T ++ ++I ++ R+ L+ W D RLS+
Sbjct: 17 YDARIRPNFKGPPVNVTCNIFINSFSSITKTTMDYRVNVFLRQQWNDPRLSYREYPDDSL 76
Query: 329 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLD 496
S + +W+PD+ N + R+ NG+V + RL + M L
Sbjct: 77 DLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLILSCLMDLK 136
Query: 497 XWPNDMQTCTFKFGS 541
+P D+QTCT + S
Sbjct: 137 NFPMDIQTCTMQLES 151
>U93917-1|AAC39917.1| 449|Homo sapiens glycine receptor alpha 3
subunit protein.
Length = 449
Score = 39.5 bits (88), Expect = 0.015
Identities = 34/135 (25%), Positives = 58/135 (42%), Gaps = 8/135 (5%)
Frame = +2
Query: 161 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 328
YD P+ K VN+T ++ +I E+ R+ L+ W D RL+++
Sbjct: 57 YDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPDDSL 116
Query: 329 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLD 496
S + +W+PD+ N + R+ NG+V + RL ++ M L
Sbjct: 117 DLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLK 176
Query: 497 XWPNDMQTCTFKFGS 541
+P D+QTC + S
Sbjct: 177 NFPMDVQTCIMQLES 191
>BC036086-1|AAH36086.1| 464|Homo sapiens glycine receptor, alpha 3
protein.
Length = 464
Score = 39.5 bits (88), Expect = 0.015
Identities = 34/135 (25%), Positives = 58/135 (42%), Gaps = 8/135 (5%)
Frame = +2
Query: 161 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 328
YD P+ K VN+T ++ +I E+ R+ L+ W D RL+++
Sbjct: 57 YDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPDDSL 116
Query: 329 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLD 496
S + +W+PD+ N + R+ NG+V + RL ++ M L
Sbjct: 117 DLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLK 176
Query: 497 XWPNDMQTCTFKFGS 541
+P D+QTC + S
Sbjct: 177 NFPMDVQTCIMQLES 191
>AF017724-1|AAC39919.1| 465|Homo sapiens glycine receptor alpha 3
subunit protein.
Length = 465
Score = 39.5 bits (88), Expect = 0.015
Identities = 34/135 (25%), Positives = 58/135 (42%), Gaps = 8/135 (5%)
Frame = +2
Query: 161 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 328
YD P+ K VN+T ++ +I E+ R+ L+ W D RL+++
Sbjct: 57 YDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPDDSL 116
Query: 329 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLD 496
S + +W+PD+ N + R+ NG+V + RL ++ M L
Sbjct: 117 DLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLK 176
Query: 497 XWPNDMQTCTFKFGS 541
+P D+QTC + S
Sbjct: 177 NFPMDVQTCIMQLES 191
>BC114967-1|AAI14968.1| 366|Homo sapiens GLRA1 protein protein.
Length = 366
Score = 38.3 bits (85), Expect = 0.035
Identities = 26/100 (26%), Positives = 44/100 (44%), Gaps = 4/100 (4%)
Frame = +2
Query: 254 RILADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERLWRPDVVLLNAAATTAGDYALR---A 421
R+ L+ W D RL++N S + +W+PD+ N +
Sbjct: 4 RVNIFLRQQWNDPRLAYNEYPDDSLDLDPSMLDSIWKPDLFFANEKGAHFHEITTDNKLL 63
Query: 422 RVSNNGSVSWIKRLDISTPISMQLDXWPNDMQTCTFKFGS 541
R+S NG+V + R+ ++ M L +P D+QTC + S
Sbjct: 64 RISRNGNVLYSIRITLTLACPMDLKNFPMDVQTCIMQLES 103
>AB209359-1|BAD92596.1| 533|Homo sapiens cholinergic receptor,
nicotinic, alpha polypeptide 4 precursor variant
protein.
Length = 533
Score = 35.9 bits (79), Expect = 0.19
Identities = 19/72 (26%), Positives = 32/72 (44%)
Frame = +2
Query: 353 LWRPDVVLLNAAATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDXWPNDMQTCTFK 532
LW +A A + +A + ++G V W + S+ + +P D Q CT K
Sbjct: 25 LWLCCCTFTSADGDFAVTHLTKAHLFHDGRVQWTPPAIYKSSCSIDVTFFPFDQQNCTMK 84
Query: 533 FGSRMXNSDEMD 568
FGS + ++D
Sbjct: 85 FGSWTYDKAKID 96
>BC096291-1|AAH96291.1| 556|Homo sapiens CHRNA4 protein protein.
Length = 556
Score = 35.1 bits (77), Expect = 0.33
Identities = 18/60 (30%), Positives = 31/60 (51%), Gaps = 4/60 (6%)
Frame = +2
Query: 401 GDYAL----RARVSNNGSVSWIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMXNSDEMD 568
GD+A+ +A + ++G V W + S+ + +P D Q CT KFGS + ++D
Sbjct: 60 GDFAVTHLTKAHLFHDGRVQWTPPAIYKSSCSIDVTFFPFDQQNCTMKFGSWTYDKAKID 119
>BC146774-1|AAI46775.1| 1114|Homo sapiens GPR124 protein protein.
Length = 1114
Score = 30.7 bits (66), Expect = 7.0
Identities = 16/55 (29%), Positives = 26/55 (47%), Gaps = 1/55 (1%)
Frame = +2
Query: 302 WNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNN-GSVSWIKRL 463
W +GEW C+ + + ++V+L T+ Y RV+NN G W + L
Sbjct: 314 WASGEWECTVSMAQGNASKKVEIVVLE----TSASYCPAERVANNRGDFRWPRTL 364
>AY181242-1|AAO27354.1| 1331|Homo sapiens G protein-coupled receptor
124 protein.
Length = 1331
Score = 30.7 bits (66), Expect = 7.0
Identities = 16/55 (29%), Positives = 26/55 (47%), Gaps = 1/55 (1%)
Frame = +2
Query: 302 WNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNN-GSVSWIKRL 463
W +GEW C+ + + ++V+L T+ Y RV+NN G W + L
Sbjct: 314 WASGEWECTVSMAQGNASKKVEIVVLE----TSASYCPAERVANNRGDFRWPRTL 364
>AK074099-1|BAB84925.1| 1310|Homo sapiens FLJ00170 protein protein.
Length = 1310
Score = 30.7 bits (66), Expect = 7.0
Identities = 16/55 (29%), Positives = 26/55 (47%), Gaps = 1/55 (1%)
Frame = +2
Query: 302 WNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNN-GSVSWIKRL 463
W +GEW C+ + + ++V+L T+ Y RV+NN G W + L
Sbjct: 293 WASGEWECTVSMAQGNASKKVEIVVLE----TSASYCPAERVANNRGDFRWPRTL 343
>AK024365-1|BAB14899.1| 1148|Homo sapiens protein ( Homo sapiens
cDNA FLJ14303 fis, clone PLACE2000132. ).
Length = 1148
Score = 30.7 bits (66), Expect = 7.0
Identities = 24/79 (30%), Positives = 31/79 (39%)
Frame = -2
Query: 739 RTTDXGPXXGXGXRNXHXPTRDSTXAXVPGXAPHXXDPSHPHXXDSNILYIXXSITEIHF 560
+ T GP P +D V H DP+ P D LY+ S H
Sbjct: 472 KNTSVGPLYSGSRLTLLRPEKDGEATGVDAICTHRPDPTGP-GLDREQLYLELS-QLTHS 529
Query: 559 VTIXHPRTELERASLHVVG 503
+T P T L+R SL+V G
Sbjct: 530 ITELGPYT-LDRDSLYVNG 547
>AF414442-1|AAL65133.2|22152|Homo sapiens ovarian cancer related tumor
marker CA125 protein.
Length = 22152
Score = 30.7 bits (66), Expect = 7.0
Identities = 24/79 (30%), Positives = 31/79 (39%)
Frame = -2
Query: 739 RTTDXGPXXGXGXRNXHXPTRDSTXAXVPGXAPHXXDPSHPHXXDSNILYIXXSITEIHF 560
+ T GP P +D V H DP+ P D LY+ S H
Sbjct: 21476 KNTSVGPLYSGSRLTLLRPEKDGEATGVDAICTHRPDPTGP-GLDREQLYLELS-QLTHS 21533
Query: 559 VTIXHPRTELERASLHVVG 503
+T P T L+R SL+V G
Sbjct: 21534 ITELGPYT-LDRDSLYVNG 21551
>AF378755-1|AAL11992.1| 1331|Homo sapiens tumor endothelial marker 5
precursor protein.
Length = 1331
Score = 30.7 bits (66), Expect = 7.0
Identities = 16/55 (29%), Positives = 26/55 (47%), Gaps = 1/55 (1%)
Frame = +2
Query: 302 WNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNN-GSVSWIKRL 463
W +GEW C+ + + ++V+L T+ Y RV+NN G W + L
Sbjct: 314 WASGEWECTVSMAQGNASKKVEIVVLE----TSASYCPAERVANNRGDFRWPRTL 364
>AB040964-1|BAA96055.2| 1206|Homo sapiens KIAA1531 protein protein.
Length = 1206
Score = 30.7 bits (66), Expect = 7.0
Identities = 16/55 (29%), Positives = 26/55 (47%), Gaps = 1/55 (1%)
Frame = +2
Query: 302 WNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNN-GSVSWIKRL 463
W +GEW C+ + + ++V+L T+ Y RV+NN G W + L
Sbjct: 406 WASGEWECTVSMAQGNASKKVEIVVLE----TSASYCPAERVANNRGDFRWPRTL 456
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 108,996,048
Number of Sequences: 237096
Number of extensions: 2404890
Number of successful extensions: 6005
Number of sequences better than 10.0: 166
Number of HSP's better than 10.0 without gapping: 5522
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5856
length of database: 76,859,062
effective HSP length: 89
effective length of database: 55,757,518
effective search space used: 10816958492
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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