Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BmNP07_FL5_B18
(859 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
AJ306454-1|CAC34819.1| 497|Homo sapiens neuronal nicotinic acet... 79 2e-14
Y08416-1|CAA69693.1| 498|Homo sapiens nicotinic acetylcholine r... 77 6e-14
U62439-1|AAB40117.1| 498|Homo sapiens nicotinic acetylcholine r... 77 6e-14
U48861-1|AAA92123.1| 498|Homo sapiens beta 4 nicotinic acetylch... 77 6e-14
BC096082-1|AAH96082.1| 498|Homo sapiens cholinergic receptor, n... 77 6e-14
BC096080-1|AAH96080.1| 498|Homo sapiens cholinergic receptor, n... 77 6e-14
AF306329-1|AAL02062.1| 498|Homo sapiens neuronal nicotinic acet... 77 6e-14
X68275-1|CAA48336.1| 451|Homo sapiens nicotinic receptor beta 4... 73 1e-12
Y08419-1|CAA69696.1| 468|Homo sapiens nicotinic acetylcholine r... 72 2e-12
Y08417-1|CAA69694.1| 458|Homo sapiens nicotinic acetylcholine r... 72 2e-12
X67513-1|CAA47851.1| 423|Homo sapiens nicotinic acetylcholine ... 72 2e-12
U62438-1|AAB40116.1| 458|Homo sapiens nicotinic acetylcholine r... 72 2e-12
U62434-1|AAB40112.1| 468|Homo sapiens nicotinic acetylcholine r... 72 2e-12
BC069788-1|AAH69788.1| 458|Homo sapiens cholinergic receptor, n... 72 2e-12
BC069703-1|AAH69703.1| 458|Homo sapiens cholinergic receptor, n... 72 2e-12
BC069681-1|AAH69681.1| 458|Homo sapiens cholinergic receptor, n... 72 2e-12
BC033639-1|AAH33639.1| 468|Homo sapiens cholinergic receptor, n... 72 2e-12
AJ306481-1|CAC34820.1| 468|Homo sapiens neuronal nicotinic acet... 72 2e-12
AF140765-1|AAD33063.1| 458|Homo sapiens neuronal acetylcholine ... 72 2e-12
M83712-1|AAA58357.1| 468|Homo sapiens nicotinic receptor alpha ... 71 5e-12
Y08418-1|CAA69695.1| 503|Homo sapiens nicotinic acetylcholine r... 70 1e-11
X53559-1|CAA37625.1| 474|Homo sapiens neuronal nicotinic acetyl... 70 1e-11
U62432-1|AAB40110.1| 504|Homo sapiens nicotinic acetylcholine r... 70 1e-11
M37981-1|AAA59942.1| 503|Homo sapiens neuronal nicotinic acetyl... 70 1e-11
BT006897-1|AAP35543.1| 505|Homo sapiens cholinergic receptor, n... 70 1e-11
BT006646-1|AAP35292.1| 489|Homo sapiens cholinergic receptor, n... 70 1e-11
BC098443-1|AAH98443.1| 504|Homo sapiens cholinergic receptor, n... 70 1e-11
BC006114-1|AAH06114.1| 489|Homo sapiens CHRNA3 protein protein. 70 1e-11
BC002996-1|AAH02996.1| 505|Homo sapiens cholinergic receptor, n... 70 1e-11
BC001642-1|AAH01642.1| 505|Homo sapiens cholinergic receptor, n... 70 1e-11
BC000513-1|AAH00513.1| 505|Homo sapiens cholinergic receptor, n... 70 1e-11
AJ007783-1|CAA07682.1| 504|Homo sapiens nicotinic acetylcholine... 70 1e-11
AF385584-1|AAK68110.1| 489|Homo sapiens nicotinic cholinergic r... 70 1e-11
Y08421-1|CAA69698.1| 627|Homo sapiens nicotinic acetylcholine r... 69 2e-11
X89741-1|CAA61893.1| 627|Homo sapiens neuronal acetylcholine re... 69 2e-11
X87629-1|CAA60959.1| 602|Homo sapiens nicotinic acetylcholine r... 69 2e-11
U62433-1|AAB40111.1| 627|Homo sapiens nicotinic acetylcholine r... 69 2e-11
L35901-1|AAA64743.1| 627|Homo sapiens nicotinic acetylcholine r... 69 2e-11
DQ093071-1|AAY88737.1| 627|Homo sapiens cholinergic receptor, n... 69 2e-11
BC096290-1|AAH96290.1| 627|Homo sapiens cholinergic receptor, n... 69 2e-11
Y08415-1|CAA69692.1| 502|Homo sapiens nicotinic acetylcholine r... 69 3e-11
X53179-1|CAA37320.1| 502|Homo sapiens precursor peptide (AA -25... 69 3e-11
U62437-1|AAB40115.1| 502|Homo sapiens nicotinic acetylcholine r... 69 3e-11
BC075041-1|AAH75041.1| 502|Homo sapiens cholinergic receptor, n... 69 3e-11
BC075040-1|AAH75040.1| 502|Homo sapiens cholinergic receptor, n... 69 3e-11
AL592078-3|CAI16184.1| 502|Homo sapiens cholinergic receptor, n... 69 3e-11
AJ001935-1|CAA05108.1| 504|Homo sapiens CHRNB2 protein. 69 3e-11
AF077186-1|AAD45422.1| 502|Homo sapiens neuronal nicotinic acet... 69 3e-11
Y16281-1|CAA76154.1| 529|Homo sapiens nicotinic acetylcholine r... 68 5e-11
U62431-1|AAB40109.1| 529|Homo sapiens nicotinic acetylcholine r... 68 5e-11
M86383-1|AAC84176.1| 502|Homo sapiens nicotinic acetylcholine r... 67 7e-11
Y16282-1|CAA76155.1| 494|Homo sapiens nicotinic acetylcholine r... 66 2e-10
U62435-1|AAB40113.1| 494|Homo sapiens nicotinic acetylcholine r... 66 2e-10
BC014456-1|AAH14456.1| 494|Homo sapiens cholinergic receptor, n... 66 2e-10
AB079251-1|BAC06855.1| 494|Homo sapiens Nicotinic acetylcholine... 66 2e-10
X66403-1|CAA47030.1| 493|Homo sapiens acetylcholine receptor ep... 63 1e-09
AF105999-1|AAD24503.1| 493|Homo sapiens acetylcholine receptor ... 63 1e-09
BC131799-1|AAI31800.1| 447|Homo sapiens 5-hydroxytryptamine (se... 62 3e-09
AF459285-1|AAL66182.1| 447|Homo sapiens 5-hydroxytryptamine rec... 62 3e-09
DQ644022-1|ABG35128.1| 456|Homo sapiens 5-HT3 receptor subunit ... 61 6e-09
BC101185-1|AAI01186.1| 374|Homo sapiens HTR3E protein protein. 61 6e-09
BC101183-1|AAI01184.1| 471|Homo sapiens 5-hydroxytryptamine (se... 61 6e-09
BC101182-1|AAI01183.1| 471|Homo sapiens 5-hydroxytryptamine (se... 61 6e-09
AY159813-1|AAO38167.2| 471|Homo sapiens 5-hydroxytryptamine ser... 61 6e-09
X14830-1|CAA32939.1| 501|Homo sapiens protein ( Human mRNA for ... 60 8e-09
X01715-1|CAA25861.1| 520|Homo sapiens acetylcholine receptor ga... 60 8e-09
BC011371-1|AAH11371.1| 501|Homo sapiens cholinergic receptor, n... 60 8e-09
AC092165-3|AAY24103.1| 520|Homo sapiens unknown protein. 60 8e-09
AY349353-1|AAQ93477.1| 456|Homo sapiens 5-HT3c1 serotonin recep... 60 1e-08
AY349352-1|AAQ93476.1| 441|Homo sapiens 5-HT3c1 serotonin recep... 60 1e-08
BC023553-1|AAH23553.1| 501|Homo sapiens cholinergic receptor, n... 59 2e-08
BC113575-1|AAI13576.1| 479|Homo sapiens cholinergic receptor, n... 59 2e-08
BC113549-1|AAI13550.1| 479|Homo sapiens cholinergic receptor, n... 59 2e-08
AY123244-1|AAM74523.1| 479|Homo sapiens nicotinic acetylcholine... 59 2e-08
AJ243342-1|CAB65091.1| 479|Homo sapiens nicotinic acetylcholine... 59 2e-08
AF227732-1|AAF61920.1| 470|Homo sapiens nicotinic acetylcholine... 59 2e-08
AC118275-1|AAY40986.1| 479|Homo sapiens unknown protein. 59 2e-08
Y00762-1|CAA68731.1| 457|Homo sapiens protein ( Human mRNA for ... 57 7e-08
X02502-1|CAA26344.1| 457|Homo sapiens acetylcholine receptor pr... 57 7e-08
S77094-1|AAD14247.1| 457|Homo sapiens nicotinic acetylcholine r... 57 7e-08
BC006314-1|AAH06314.1| 269|Homo sapiens CHRNA1 protein protein. 57 7e-08
AJ295237-1|CAC16144.1| 450|Homo sapiens neuronal nicotinic acet... 57 7e-08
AJ278118-1|CAC20435.1| 450|Homo sapiens neuronal nicotinic acet... 57 7e-08
AF327367-1|AAK14333.1| 450|Homo sapiens nicotinic acetylcholine... 57 7e-08
AF199235-1|AAG00795.2| 450|Homo sapiens nicotinic acetylcholine... 57 7e-08
AC018890-1|AAY14687.1| 457|Homo sapiens unknown protein. 57 7e-08
X55019-1|CAA38759.1| 517|Homo sapiens acetylcholine receptor de... 56 1e-07
BC093925-1|AAH93925.1| 517|Homo sapiens cholinergic receptor, n... 56 1e-07
BC093923-1|AAH93923.1| 517|Homo sapiens cholinergic receptor, n... 56 1e-07
AC092165-2|AAY24102.1| 517|Homo sapiens unknown protein. 56 1e-07
Z23141-1|CAA80672.1| 479|Homo sapiens cholinergic receptor, nic... 56 2e-07
Y08420-1|CAA69697.1| 502|Homo sapiens nicotinic acetylcholine r... 56 2e-07
X70297-1|CAA49778.1| 502|Homo sapiens neuronal nicotinic acetyl... 56 2e-07
U62436-1|AAB40114.1| 502|Homo sapiens nicotinic acetylcholine r... 56 2e-07
AJ586911-1|CAE52911.1| 502|Homo sapiens nicotinic acetylcholine... 56 2e-07
U40583-1|AAA83561.1| 502|Homo sapiens alpha 7 neuronal nicotini... 55 4e-07
AF385585-1|AAK68111.1| 502|Homo sapiens nicotinic cholinergic r... 55 4e-07
M59216-1|AAA35862.1| 474|Homo sapiens gamma-aminobutyric acid r... 52 2e-06
BC110597-1|AAI10598.1| 411|Homo sapiens ligand-gated ion channe... 52 2e-06
AF512521-1|AAO20969.1| 411|Homo sapiens ligand-gated ion channe... 52 2e-06
AB223030-1|BAE19924.1| 411|Homo sapiens ligand-gated ion-channe... 52 3e-06
X14767-1|CAA32875.1| 474|Homo sapiens GABA-A receptor beta 1 su... 52 4e-06
BC111802-1|AAI11803.1| 465|Homo sapiens CHRNG protein protein. 52 4e-06
AK122638-1|BAC85499.1| 266|Homo sapiens yte protein of 76kDa) (... 51 5e-06
S77554-1|AAB33983.1| 474|Homo sapiens GABAA receptor beta 2 sub... 51 6e-06
S77553-1|AAB33982.1| 512|Homo sapiens GABAA receptor beta 2 sub... 51 6e-06
S67368-1|AAB29370.1| 474|Homo sapiens gamma-aminobutyric acid A... 51 6e-06
L08485-1|AAA58490.1| 462|Homo sapiens GABA-benzodiazepine recep... 51 6e-06
BT009830-1|AAP88832.1| 462|Homo sapiens gamma-aminobutyric acid... 51 6e-06
BC113422-1|AAI13423.1| 462|Homo sapiens gamma-aminobutyric acid... 51 6e-06
BC111979-1|AAI11980.1| 462|Homo sapiens gamma-aminobutyric acid... 51 6e-06
BC105639-1|AAI05640.1| 474|Homo sapiens GABRB2 protein protein. 51 6e-06
BC099719-1|AAH99719.1| 474|Homo sapiens GABRB2 protein protein. 51 6e-06
BC099705-1|AAH99705.1| 474|Homo sapiens GABRB2 protein protein. 51 6e-06
S81944-1|AAB36480.1| 453|Homo sapiens gamma-aminobutyric acid t... 50 1e-05
BC099641-1|AAH99641.1| 453|Homo sapiens gamma-aminobutyric acid... 50 1e-05
BC099640-1|AAH99640.1| 453|Homo sapiens gamma-aminobutyric acid... 50 1e-05
BC096242-1|AAH96242.1| 453|Homo sapiens gamma-aminobutyric acid... 50 1e-05
BC096241-1|AAH96241.1| 453|Homo sapiens gamma-aminobutyric acid... 50 1e-05
U77731-2|AAB38273.1| 360|Homo sapiens glycine receptor alpha 2B... 49 2e-05
CR450343-1|CAG29339.1| 452|Homo sapiens GLRA2 protein. 49 2e-05
AY437084-1|AAR87843.1| 452|Homo sapiens glycine receptor alpha2... 49 2e-05
X52008-1|CAA36257.1| 452|Homo sapiens inhibitory glycine recept... 49 3e-05
U77731-1|AAB38272.1| 360|Homo sapiens glycine receptor alpha 2 ... 49 3e-05
BC032864-1|AAH32864.1| 452|Homo sapiens glycine receptor, alpha... 49 3e-05
BC028629-1|AAH28629.1| 492|Homo sapiens gamma-aminobutyric acid... 49 3e-05
AY437083-1|AAR87842.1| 452|Homo sapiens glycine receptor alpha2... 49 3e-05
AJ003080-1|CAA05853.1| 238|Homo sapiens serotonin receptor prot... 49 3e-05
AF053495-1|AAC35290.1| 452|Homo sapiens glycine receptor alpha ... 49 3e-05
S62908-1|AAB27279.1| 492|Homo sapiens gamma-aminobutyric acidA ... 48 3e-05
BC096083-1|AAH96083.1| 198|Homo sapiens CHRNB4 protein protein. 48 3e-05
BC096081-1|AAH96081.1| 198|Homo sapiens CHRNB4 protein protein. 48 3e-05
BC033801-1|AAH33801.1| 452|Homo sapiens gamma-aminobutyric acid... 48 3e-05
AL391845-4|CAI15436.1| 452|Homo sapiens gamma-aminobutyric acid... 48 3e-05
AF166361-1|AAG12455.1| 492|Homo sapiens GABA receptor subunit a... 48 3e-05
AF016917-1|AAB70007.1| 452|Homo sapiens GABA-A receptor delta s... 48 3e-05
U30461-1|AAB52519.1| 554|Homo sapiens GABAA receptor subunit al... 48 4e-05
BC035055-1|AAH35055.1| 554|Homo sapiens gamma-aminobutyric acid... 48 4e-05
S82612-1|AAB37533.2| 478|Homo sapiens 5-hydroxytryptamine type ... 48 6e-05
S82769-1|AAB39369.1| 467|Homo sapiens GABAA receptor gamma 3 su... 47 8e-05
D49394-1|BAA08387.1| 478|Homo sapiens serotonin 5-HT3 receptor ... 47 8e-05
BT007204-1|AAP35868.1| 484|Homo sapiens 5-hydroxytryptamine (se... 47 8e-05
BC022449-1|AAH22449.1| 474|Homo sapiens gamma-aminobutyric acid... 47 8e-05
BC004453-1|AAH04453.2| 478|Homo sapiens 5-hydroxytryptamine (se... 47 8e-05
BC002354-1|AAH02354.1| 478|Homo sapiens 5-hydroxytryptamine (se... 47 8e-05
AJ005205-1|CAA06442.3| 478|Homo sapiens serotonin 3 receptor pr... 47 8e-05
AJ003079-1|CAA05852.1| 478|Homo sapiens 5-hydroxytryptamine3 re... 47 8e-05
AJ003078-1|CAA05851.1| 510|Homo sapiens serotonin receptor prot... 47 8e-05
AF498984-1|AAM21131.1| 478|Homo sapiens 5-hydroxytryptamine rec... 47 8e-05
AF269144-1|AAF99698.1| 467|Homo sapiens GABAA receptor gamma 3 ... 47 8e-05
AF228458-1|AAF63215.1| 449|Homo sapiens GABAA receptor gamma 3 ... 47 8e-05
U95367-1|AAC51357.1| 440|Homo sapiens GABA-A receptor pi subuni... 47 1e-04
BC109106-1|AAI09107.1| 440|Homo sapiens gamma-aminobutyric acid... 47 1e-04
BC109105-1|AAI09106.1| 440|Homo sapiens gamma-aminobutyric acid... 47 1e-04
BC074865-1|AAH74865.1| 440|Homo sapiens gamma-aminobutyric acid... 47 1e-04
BC074810-1|AAH74810.1| 440|Homo sapiens gamma-aminobutyric acid... 47 1e-04
AF009702-1|AAC24194.1| 440|Homo sapiens GABA-A receptor pi subu... 47 1e-04
BC109211-1|AAI09212.1| 632|Homo sapiens gamma-aminobutyric acid... 46 2e-04
BC109210-1|AAI09211.1| 632|Homo sapiens gamma-aminobutyric acid... 46 2e-04
AF189259-1|AAF70380.1| 632|Homo sapiens GABA-A receptor theta s... 46 2e-04
AF144648-1|AAD51172.1| 627|Homo sapiens GABA-A receptor theta p... 46 2e-04
X52009-1|CAA36258.1| 449|Homo sapiens inhibitory glycine recept... 45 3e-04
BC114947-1|AAI14948.1| 457|Homo sapiens GLRA1 protein protein. 45 3e-04
BC074980-1|AAH74980.1| 449|Homo sapiens glycine receptor, alpha... 45 3e-04
Z93848-1|CAI41994.1| 376|Homo sapiens glycine receptor, alpha 4... 44 0.001
AL049610-1|CAI42158.1| 376|Homo sapiens glycine receptor, alpha... 44 0.001
AB209359-1|BAD92596.1| 533|Homo sapiens cholinergic receptor, n... 43 0.001
U93917-1|AAC39917.1| 449|Homo sapiens glycine receptor alpha 3 ... 43 0.002
BC036086-1|AAH36086.1| 464|Homo sapiens glycine receptor, alpha... 43 0.002
AF017724-1|AAC39919.1| 465|Homo sapiens glycine receptor alpha ... 43 0.002
BC096291-1|AAH96291.1| 556|Homo sapiens CHRNA4 protein protein. 42 0.002
BC114967-1|AAI14968.1| 366|Homo sapiens GLRA1 protein protein. 42 0.003
BC031087-1|AAH31087.1| 465|Homo sapiens gamma-aminobutyric acid... 42 0.004
BC074795-1|AAH74795.1| 467|Homo sapiens gamma-aminobutyric acid... 41 0.007
BC069348-1|AAH69348.1| 467|Homo sapiens gamma-aminobutyric acid... 41 0.007
BC059389-1|AAH59389.1| 475|Homo sapiens gamma-aminobutyric acid... 41 0.007
AF165124-1|AAD50273.1| 467|Homo sapiens gamma-aminobutyric acid... 41 0.007
X15376-1|CAA33437.1| 467|Homo sapiens GABA-A receptor gamma 2 s... 40 0.012
AK093764-1|BAC04222.1| 360|Homo sapiens protein ( Homo sapiens ... 33 1.3
S56526-1|AAB19910.2| 138|Homo sapiens T cell receptor alpha cha... 31 7.1
BC146774-1|AAI46775.1| 1114|Homo sapiens GPR124 protein protein. 31 7.1
AY181242-1|AAO27354.1| 1331|Homo sapiens G protein-coupled recep... 31 7.1
AK074099-1|BAB84925.1| 1310|Homo sapiens FLJ00170 protein protein. 31 7.1
AF378755-1|AAL11992.1| 1331|Homo sapiens tumor endothelial marke... 31 7.1
AB040964-1|BAA96055.2| 1206|Homo sapiens KIAA1531 protein protein. 31 7.1
>AJ306454-1|CAC34819.1| 497|Homo sapiens neuronal nicotinic
acetylcholine receptor beta-4 subunit protein.
Length = 497
Score = 79.4 bits (187), Expect = 2e-14
Identities = 54/192 (28%), Positives = 88/192 (45%), Gaps = 11/192 (5%)
Frame = +2
Query: 92 AIASAAECENATSLSLMIDSLL--ATYDRESPP--DSKIVVNLTLHLRHA---SIRESES 250
A+ C A + ++D LL Y+ P S ++++ L L A S+ E E
Sbjct: 14 ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQ 73
Query: 251 TVRMLAGLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRAR 427
+ L+ W D RL+WN+ + G + + ++R+W PD+VL N T
Sbjct: 74 IMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNDGTYEVSVYTNLI 133
Query: 428 VSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDXMDFVIDKRIYSMFE 607
V +NGSV W+ + +++ +P D Q CT KF S ++ +D V+ SM +
Sbjct: 134 VRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRSWTYDHTEIDMVLMTPTASMDD 193
Query: 608 ---SGAWDVTDL 634
SG WD+ L
Sbjct: 194 FTPSGEWDIVAL 205
>Y08416-1|CAA69693.1| 498|Homo sapiens nicotinic acetylcholine
receptor beta4 subunit precursor protein.
Length = 498
Score = 77.4 bits (182), Expect = 6e-14
Identities = 55/193 (28%), Positives = 89/193 (46%), Gaps = 12/193 (6%)
Frame = +2
Query: 92 AIASAAECENATSLSLMIDSLL--ATYDRESPP--DSKIVVNLTLHLRHA---SIRESES 250
A+ C A + ++D LL Y+ P S ++++ L L A S+ E E
Sbjct: 14 ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQ 73
Query: 251 TVRMLAGLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRA 424
+ L+ W D RL+WN+ + G + + ++R+W PD+VL N A T
Sbjct: 74 IMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNADGTYEVSVYTNL 133
Query: 425 RVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDXMDFVIDKRIYSMF 604
V +NGSV W+ + +++ +P D Q CT KF S ++ +D V+ SM
Sbjct: 134 IVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRSWTYDHTEIDMVLMTPTASMD 193
Query: 605 E---SGAWDVTDL 634
+ SG WD+ L
Sbjct: 194 DFTPSGEWDIVAL 206
>U62439-1|AAB40117.1| 498|Homo sapiens nicotinic acetylcholine
receptor beta4 subunit precursor protein.
Length = 498
Score = 77.4 bits (182), Expect = 6e-14
Identities = 55/193 (28%), Positives = 89/193 (46%), Gaps = 12/193 (6%)
Frame = +2
Query: 92 AIASAAECENATSLSLMIDSLL--ATYDRESPP--DSKIVVNLTLHLRHA---SIRESES 250
A+ C A + ++D LL Y+ P S ++++ L L A S+ E E
Sbjct: 14 ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQ 73
Query: 251 TVRMLAGLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRA 424
+ L+ W D RL+WN+ + G + + ++R+W PD+VL N A T
Sbjct: 74 IMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNADGTYEVSVYTNL 133
Query: 425 RVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDXMDFVIDKRIYSMF 604
V +NGSV W+ + +++ +P D Q CT KF S ++ +D V+ SM
Sbjct: 134 IVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRSWTYDHTEIDMVLMTPTASMD 193
Query: 605 E---SGAWDVTDL 634
+ SG WD+ L
Sbjct: 194 DFTPSGEWDIVAL 206
>U48861-1|AAA92123.1| 498|Homo sapiens beta 4 nicotinic
acetylcholine receptor subunit protein.
Length = 498
Score = 77.4 bits (182), Expect = 6e-14
Identities = 55/193 (28%), Positives = 89/193 (46%), Gaps = 12/193 (6%)
Frame = +2
Query: 92 AIASAAECENATSLSLMIDSLL--ATYDRESPP--DSKIVVNLTLHLRHA---SIRESES 250
A+ C A + ++D LL Y+ P S ++++ L L A S+ E E
Sbjct: 14 ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQ 73
Query: 251 TVRMLAGLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRA 424
+ L+ W D RL+WN+ + G + + ++R+W PD+VL N A T
Sbjct: 74 IMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNADGTYEVSVYTNL 133
Query: 425 RVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDXMDFVIDKRIYSMF 604
V +NGSV W+ + +++ +P D Q CT KF S ++ +D V+ SM
Sbjct: 134 IVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRSWTYDHTEIDMVLMTPTASMD 193
Query: 605 E---SGAWDVTDL 634
+ SG WD+ L
Sbjct: 194 DFTPSGEWDIVAL 206
>BC096082-1|AAH96082.1| 498|Homo sapiens cholinergic receptor,
nicotinic, beta 4 protein.
Length = 498
Score = 77.4 bits (182), Expect = 6e-14
Identities = 55/193 (28%), Positives = 89/193 (46%), Gaps = 12/193 (6%)
Frame = +2
Query: 92 AIASAAECENATSLSLMIDSLL--ATYDRESPP--DSKIVVNLTLHLRHA---SIRESES 250
A+ C A + ++D LL Y+ P S ++++ L L A S+ E E
Sbjct: 14 ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQ 73
Query: 251 TVRMLAGLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRA 424
+ L+ W D RL+WN+ + G + + ++R+W PD+VL N A T
Sbjct: 74 IMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNADGTYEVSVYTNL 133
Query: 425 RVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDXMDFVIDKRIYSMF 604
V +NGSV W+ + +++ +P D Q CT KF S ++ +D V+ SM
Sbjct: 134 IVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRSWTYDHTEIDMVLMTPTASMD 193
Query: 605 E---SGAWDVTDL 634
+ SG WD+ L
Sbjct: 194 DFTPSGEWDIVAL 206
>BC096080-1|AAH96080.1| 498|Homo sapiens cholinergic receptor,
nicotinic, beta 4 protein.
Length = 498
Score = 77.4 bits (182), Expect = 6e-14
Identities = 55/193 (28%), Positives = 89/193 (46%), Gaps = 12/193 (6%)
Frame = +2
Query: 92 AIASAAECENATSLSLMIDSLL--ATYDRESPP--DSKIVVNLTLHLRHA---SIRESES 250
A+ C A + ++D LL Y+ P S ++++ L L A S+ E E
Sbjct: 14 ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQ 73
Query: 251 TVRMLAGLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRA 424
+ L+ W D RL+WN+ + G + + ++R+W PD+VL N A T
Sbjct: 74 IMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNADGTYEVSVYTNL 133
Query: 425 RVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDXMDFVIDKRIYSMF 604
V +NGSV W+ + +++ +P D Q CT KF S ++ +D V+ SM
Sbjct: 134 IVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRSWTYDHTEIDMVLMTPTASMD 193
Query: 605 E---SGAWDVTDL 634
+ SG WD+ L
Sbjct: 194 DFTPSGEWDIVAL 206
>AF306329-1|AAL02062.1| 498|Homo sapiens neuronal nicotinic
acetylcholine receptor beta 4 subunit protein.
Length = 498
Score = 77.4 bits (182), Expect = 6e-14
Identities = 55/193 (28%), Positives = 89/193 (46%), Gaps = 12/193 (6%)
Frame = +2
Query: 92 AIASAAECENATSLSLMIDSLL--ATYDRESPP--DSKIVVNLTLHLRHA---SIRESES 250
A+ C A + ++D LL Y+ P S ++++ L L A S+ E E
Sbjct: 14 ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQ 73
Query: 251 TVRMLAGLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRA 424
+ L+ W D RL+WN+ + G + + ++R+W PD+VL N A T
Sbjct: 74 IMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNADGTYEVSVYTNL 133
Query: 425 RVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDXMDFVIDKRIYSMF 604
V +NGSV W+ + +++ +P D Q CT KF S ++ +D V+ SM
Sbjct: 134 IVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRSWTYDHTEIDMVLMTPTASMD 193
Query: 605 E---SGAWDVTDL 634
+ SG WD+ L
Sbjct: 194 DFTPSGEWDIVAL 206
>X68275-1|CAA48336.1| 451|Homo sapiens nicotinic receptor beta 4
subunit protein.
Length = 451
Score = 73.3 bits (172), Expect = 1e-12
Identities = 46/153 (30%), Positives = 73/153 (47%), Gaps = 6/153 (3%)
Frame = +2
Query: 194 IVVNLTLHLRHA-SIRESESTVRMLAGLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 367
I + L L L S+ E + + L+ W D RL+WN+ + G + + ++R+W P
Sbjct: 7 ISIKLQLSLAQLISVNERDEIMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLP 66
Query: 368 DVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 544
D+VL N A T V +NGSV W+ + +++ +P D Q CT KF S
Sbjct: 67 DIVLYNNADGTYEVSVYTNLIVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRS 126
Query: 545 RMHNSDXMDFVIDKRIYSMFE---SGAWDVTDL 634
++ +D V+ SM + SG WD+ L
Sbjct: 127 WTYDHTEIDMVLMTPTASMDDFTPSGEWDIVAL 159
>Y08419-1|CAA69696.1| 468|Homo sapiens nicotinic acetylcholine
receptor alpha5 subunit precursor protein.
Length = 468
Score = 72.1 bits (169), Expect = 2e-12
Identities = 43/179 (24%), Positives = 83/179 (46%), Gaps = 11/179 (6%)
Frame = +2
Query: 140 MIDSLLATYDRESPP----DSKIVVNLTLHLRH-ASIRESESTVRMLAGLQMNWIDKRLS 304
++ L Y+R P + KI + L + + E + L+ WID +L
Sbjct: 50 LLKDLFQDYERWVRPVEHLNDKIKIKFGLAISQLVDVDEKNQLMTTNVWLKQEWIDVKLR 109
Query: 305 WNAGEWG-CSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVSWIKRLDISTP 481
WN ++G V S+ +W PD+VL + A + + + NG+V+W + +
Sbjct: 110 WNPDDYGGIKVIRVPSDSVWTPDIVLFDNADGRFEGTSTKTVIRYNGTVTWTPPANYKSS 169
Query: 482 ISMQLDNWPNDMQTCTFKFGSRMHNSDXMDFV-----IDKRIYSMFESGAWDVTDLSSA 643
++ + +P D+Q C+ KFGS ++ +D + +DKR F++G W++ + +
Sbjct: 170 CTIDVTFFPFDLQNCSMKFGSWTYDGSQVDIILEDQDVDKR--DFFDNGEWEIVSATGS 226
>Y08417-1|CAA69694.1| 458|Homo sapiens nicotinic acetylcholine
receptor beta3 subunit precursor protein.
Length = 458
Score = 72.1 bits (169), Expect = 2e-12
Identities = 38/123 (30%), Positives = 63/123 (51%), Gaps = 5/123 (4%)
Frame = +2
Query: 272 LQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLL-NAAATTAGDYALRARVSNNGS 445
L+ W D +L WN ++G + V SE LW PD+VL NA G + V +NG+
Sbjct: 81 LKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFEGSLMTKVIVKSNGT 140
Query: 446 VSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDXMDFV-IDKRI--YSMFESGA 616
V W + +M + +P D Q C+ KFGS ++ +D + I++ + F++G
Sbjct: 141 VVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGTMVDLILINENVDRKDFFDNGE 200
Query: 617 WDV 625
W++
Sbjct: 201 WEI 203
>X67513-1|CAA47851.1| 423|Homo sapiens nicotinic acetylcholine
receptor beta-3 subunit protein.
Length = 423
Score = 72.1 bits (169), Expect = 2e-12
Identities = 38/123 (30%), Positives = 63/123 (51%), Gaps = 5/123 (4%)
Frame = +2
Query: 272 LQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLL-NAAATTAGDYALRARVSNNGS 445
L+ W D +L WN ++G + V SE LW PD+VL NA G + V +NG+
Sbjct: 46 LKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFEGSLMTKVIVKSNGT 105
Query: 446 VSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDXMDFV-IDKRI--YSMFESGA 616
V W + +M + +P D Q C+ KFGS ++ +D + I++ + F++G
Sbjct: 106 VVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGTMVDLILINENVDRKDFFDNGE 165
Query: 617 WDV 625
W++
Sbjct: 166 WEI 168
>U62438-1|AAB40116.1| 458|Homo sapiens nicotinic acetylcholine
receptor beta3 subunit precursor protein.
Length = 458
Score = 72.1 bits (169), Expect = 2e-12
Identities = 38/123 (30%), Positives = 63/123 (51%), Gaps = 5/123 (4%)
Frame = +2
Query: 272 LQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLL-NAAATTAGDYALRARVSNNGS 445
L+ W D +L WN ++G + V SE LW PD+VL NA G + V +NG+
Sbjct: 81 LKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFEGSLMTKVIVKSNGT 140
Query: 446 VSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDXMDFV-IDKRI--YSMFESGA 616
V W + +M + +P D Q C+ KFGS ++ +D + I++ + F++G
Sbjct: 141 VVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGTMVDLILINENVDRKDFFDNGE 200
Query: 617 WDV 625
W++
Sbjct: 201 WEI 203
>U62434-1|AAB40112.1| 468|Homo sapiens nicotinic acetylcholine
receptor alpha5 subunit precursor protein.
Length = 468
Score = 72.1 bits (169), Expect = 2e-12
Identities = 43/179 (24%), Positives = 83/179 (46%), Gaps = 11/179 (6%)
Frame = +2
Query: 140 MIDSLLATYDRESPP----DSKIVVNLTLHLRH-ASIRESESTVRMLAGLQMNWIDKRLS 304
++ L Y+R P + KI + L + + E + L+ WID +L
Sbjct: 50 LLKDLFQDYERWVRPVEHLNDKIKIKFGLAISQLVDVDEKNQLMTTNVWLKQEWIDVKLR 109
Query: 305 WNAGEWG-CSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVSWIKRLDISTP 481
WN ++G V S+ +W PD+VL + A + + + NG+V+W + +
Sbjct: 110 WNPDDYGGIKVIRVPSDSVWTPDIVLFDNADGRFEGTSTKTVIRYNGTVTWTPPANYKSS 169
Query: 482 ISMQLDNWPNDMQTCTFKFGSRMHNSDXMDFV-----IDKRIYSMFESGAWDVTDLSSA 643
++ + +P D+Q C+ KFGS ++ +D + +DKR F++G W++ + +
Sbjct: 170 CTIDVTFFPFDLQNCSMKFGSWTYDGSQVDIILEDQDVDKR--DFFDNGEWEIVSATGS 226
>BC069788-1|AAH69788.1| 458|Homo sapiens cholinergic receptor,
nicotinic, beta 3 protein.
Length = 458
Score = 72.1 bits (169), Expect = 2e-12
Identities = 38/123 (30%), Positives = 63/123 (51%), Gaps = 5/123 (4%)
Frame = +2
Query: 272 LQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLL-NAAATTAGDYALRARVSNNGS 445
L+ W D +L WN ++G + V SE LW PD+VL NA G + V +NG+
Sbjct: 81 LKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFEGSLMTKVIVKSNGT 140
Query: 446 VSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDXMDFV-IDKRI--YSMFESGA 616
V W + +M + +P D Q C+ KFGS ++ +D + I++ + F++G
Sbjct: 141 VVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGTMVDLILINENVDRKDFFDNGE 200
Query: 617 WDV 625
W++
Sbjct: 201 WEI 203
>BC069703-1|AAH69703.1| 458|Homo sapiens cholinergic receptor,
nicotinic, beta 3 protein.
Length = 458
Score = 72.1 bits (169), Expect = 2e-12
Identities = 38/123 (30%), Positives = 63/123 (51%), Gaps = 5/123 (4%)
Frame = +2
Query: 272 LQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLL-NAAATTAGDYALRARVSNNGS 445
L+ W D +L WN ++G + V SE LW PD+VL NA G + V +NG+
Sbjct: 81 LKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFEGSLMTKVIVKSNGT 140
Query: 446 VSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDXMDFV-IDKRI--YSMFESGA 616
V W + +M + +P D Q C+ KFGS ++ +D + I++ + F++G
Sbjct: 141 VVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGTMVDLILINENVDRKDFFDNGE 200
Query: 617 WDV 625
W++
Sbjct: 201 WEI 203
>BC069681-1|AAH69681.1| 458|Homo sapiens cholinergic receptor,
nicotinic, beta 3 protein.
Length = 458
Score = 72.1 bits (169), Expect = 2e-12
Identities = 38/123 (30%), Positives = 63/123 (51%), Gaps = 5/123 (4%)
Frame = +2
Query: 272 LQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLL-NAAATTAGDYALRARVSNNGS 445
L+ W D +L WN ++G + V SE LW PD+VL NA G + V +NG+
Sbjct: 81 LKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFEGSLMTKVIVKSNGT 140
Query: 446 VSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDXMDFV-IDKRI--YSMFESGA 616
V W + +M + +P D Q C+ KFGS ++ +D + I++ + F++G
Sbjct: 141 VVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGTMVDLILINENVDRKDFFDNGE 200
Query: 617 WDV 625
W++
Sbjct: 201 WEI 203
>BC033639-1|AAH33639.1| 468|Homo sapiens cholinergic receptor,
nicotinic, alpha 5 protein.
Length = 468
Score = 72.1 bits (169), Expect = 2e-12
Identities = 43/179 (24%), Positives = 83/179 (46%), Gaps = 11/179 (6%)
Frame = +2
Query: 140 MIDSLLATYDRESPP----DSKIVVNLTLHLRH-ASIRESESTVRMLAGLQMNWIDKRLS 304
++ L Y+R P + KI + L + + E + L+ WID +L
Sbjct: 50 LLKDLFQDYERWVRPVEHLNDKIKIKFGLAISQLVDVDEKNQLMTTNVWLKQEWIDVKLR 109
Query: 305 WNAGEWG-CSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVSWIKRLDISTP 481
WN ++G V S+ +W PD+VL + A + + + NG+V+W + +
Sbjct: 110 WNPDDYGGIKVIRVPSDSVWTPDIVLFDNADGRFEGTSTKTVIRYNGTVTWTPPANYKSS 169
Query: 482 ISMQLDNWPNDMQTCTFKFGSRMHNSDXMDFV-----IDKRIYSMFESGAWDVTDLSSA 643
++ + +P D+Q C+ KFGS ++ +D + +DKR F++G W++ + +
Sbjct: 170 CTIDVTFFPFDLQNCSMKFGSWTYDGSQVDIILEDQDVDKR--DFFDNGEWEIVSATGS 226
>AJ306481-1|CAC34820.1| 468|Homo sapiens neuronal nicotinic
acetylcholine receptor alpha-5subunit protein.
Length = 468
Score = 72.1 bits (169), Expect = 2e-12
Identities = 43/179 (24%), Positives = 83/179 (46%), Gaps = 11/179 (6%)
Frame = +2
Query: 140 MIDSLLATYDRESPP----DSKIVVNLTLHLRH-ASIRESESTVRMLAGLQMNWIDKRLS 304
++ L Y+R P + KI + L + + E + L+ WID +L
Sbjct: 50 LLKDLFQDYERWVRPVEHLNDKIKIKFGLAISQLVDVDEKNQLMTTNVWLKQEWIDVKLR 109
Query: 305 WNAGEWG-CSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVSWIKRLDISTP 481
WN ++G V S+ +W PD+VL + A + + + NG+V+W + +
Sbjct: 110 WNPDDYGGIKVIRVPSDSVWTPDIVLFDNADGRFEGTSTKTVIRYNGTVTWTPPANYKSS 169
Query: 482 ISMQLDNWPNDMQTCTFKFGSRMHNSDXMDFV-----IDKRIYSMFESGAWDVTDLSSA 643
++ + +P D+Q C+ KFGS ++ +D + +DKR F++G W++ + +
Sbjct: 170 CTIDVTFFPFDLQNCSMKFGSWTYDGSQVDIILEDQDVDKR--DFFDNGEWEIVSATGS 226
>AF140765-1|AAD33063.1| 458|Homo sapiens neuronal acetylcholine
receptor beta-3 subunit precursor protein.
Length = 458
Score = 72.1 bits (169), Expect = 2e-12
Identities = 38/123 (30%), Positives = 63/123 (51%), Gaps = 5/123 (4%)
Frame = +2
Query: 272 LQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLL-NAAATTAGDYALRARVSNNGS 445
L+ W D +L WN ++G + V SE LW PD+VL NA G + V +NG+
Sbjct: 81 LKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFEGSLMTKVIVKSNGT 140
Query: 446 VSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDXMDFV-IDKRI--YSMFESGA 616
V W + +M + +P D Q C+ KFGS ++ +D + I++ + F++G
Sbjct: 141 VVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGTMVDLILINENVDRKDFFDNGE 200
Query: 617 WDV 625
W++
Sbjct: 201 WEI 203
>M83712-1|AAA58357.1| 468|Homo sapiens nicotinic receptor alpha 5
subunit protein.
Length = 468
Score = 70.9 bits (166), Expect = 5e-12
Identities = 43/179 (24%), Positives = 82/179 (45%), Gaps = 11/179 (6%)
Frame = +2
Query: 140 MIDSLLATYDRESPP----DSKIVVNLTLHLRH-ASIRESESTVRMLAGLQMNWIDKRLS 304
++ L Y+R P + KI + L + + E + L+ WID +L
Sbjct: 50 LLKDLFQDYERWVRPVEHLNDKIKIKFGLAISQLVDVDEKNQLMTTNVWLKQEWIDVKLR 109
Query: 305 WNAGEWG-CSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVSWIKRLDISTP 481
WN ++G V S+ W PD+VL + A + + + NG+V+W + +
Sbjct: 110 WNPDDYGGIKVIRVPSDSSWTPDIVLFDNADGRFEGTSTKTVIRYNGTVTWTPPANYKSS 169
Query: 482 ISMQLDNWPNDMQTCTFKFGSRMHNSDXMDFV-----IDKRIYSMFESGAWDVTDLSSA 643
++ + +P D+Q C+ KFGS ++ +D + +DKR F++G W++ + +
Sbjct: 170 CTIDVTFFPFDLQNCSMKFGSWTYDGSQVDIILEDQDVDKR--DFFDNGEWEIVSATGS 226
>Y08418-1|CAA69695.1| 503|Homo sapiens nicotinic acetylcholine
receptor alpha3 subunit precursor protein.
Length = 503
Score = 69.7 bits (163), Expect = 1e-11
Identities = 36/123 (29%), Positives = 63/123 (51%), Gaps = 5/123 (4%)
Frame = +2
Query: 272 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 445
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 85 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 144
Query: 446 VSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDXMDFVI---DKRIYSMFESGA 616
V+WI + + + +P D Q CT KFGS ++ +D V+ + +ESG
Sbjct: 145 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVLIGSSMNLKDYWESGE 204
Query: 617 WDV 625
W +
Sbjct: 205 WAI 207
>X53559-1|CAA37625.1| 474|Homo sapiens neuronal nicotinic
acetylcholine receptor alpha-3merase protein.
Length = 474
Score = 69.7 bits (163), Expect = 1e-11
Identities = 36/123 (29%), Positives = 63/123 (51%), Gaps = 5/123 (4%)
Frame = +2
Query: 272 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 445
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 56 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 115
Query: 446 VSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDXMDFVI---DKRIYSMFESGA 616
V+WI + + + +P D Q CT KFGS ++ +D V+ + +ESG
Sbjct: 116 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVLIGSSMNLKDYWESGE 175
Query: 617 WDV 625
W +
Sbjct: 176 WAI 178
>U62432-1|AAB40110.1| 504|Homo sapiens nicotinic acetylcholine
receptor alpha3 subunit precursor protein.
Length = 504
Score = 69.7 bits (163), Expect = 1e-11
Identities = 36/123 (29%), Positives = 63/123 (51%), Gaps = 5/123 (4%)
Frame = +2
Query: 272 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 445
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 86 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 145
Query: 446 VSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDXMDFVI---DKRIYSMFESGA 616
V+WI + + + +P D Q CT KFGS ++ +D V+ + +ESG
Sbjct: 146 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVLIGSSMNLKDYWESGE 205
Query: 617 WDV 625
W +
Sbjct: 206 WAI 208
>M37981-1|AAA59942.1| 503|Homo sapiens neuronal nicotinic
acetylcholine receptor protein.
Length = 503
Score = 69.7 bits (163), Expect = 1e-11
Identities = 36/123 (29%), Positives = 63/123 (51%), Gaps = 5/123 (4%)
Frame = +2
Query: 272 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 445
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 85 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 144
Query: 446 VSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDXMDFVI---DKRIYSMFESGA 616
V+WI + + + +P D Q CT KFGS ++ +D V+ + +ESG
Sbjct: 145 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVLIGSSMNLKDYWESGE 204
Query: 617 WDV 625
W +
Sbjct: 205 WAI 207
>BT006897-1|AAP35543.1| 505|Homo sapiens cholinergic receptor,
nicotinic, alpha polypeptide 3 protein.
Length = 505
Score = 69.7 bits (163), Expect = 1e-11
Identities = 36/123 (29%), Positives = 63/123 (51%), Gaps = 5/123 (4%)
Frame = +2
Query: 272 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 445
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 87 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 146
Query: 446 VSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDXMDFVI---DKRIYSMFESGA 616
V+WI + + + +P D Q CT KFGS ++ +D V+ + +ESG
Sbjct: 147 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVLIGSSMNLKDYWESGE 206
Query: 617 WDV 625
W +
Sbjct: 207 WAI 209
>BT006646-1|AAP35292.1| 489|Homo sapiens cholinergic receptor,
nicotinic, alpha polypeptide 3 protein.
Length = 489
Score = 69.7 bits (163), Expect = 1e-11
Identities = 36/123 (29%), Positives = 63/123 (51%), Gaps = 5/123 (4%)
Frame = +2
Query: 272 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 445
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 87 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 146
Query: 446 VSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDXMDFVI---DKRIYSMFESGA 616
V+WI + + + +P D Q CT KFGS ++ +D V+ + +ESG
Sbjct: 147 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVLIGSSMNLKDYWESGE 206
Query: 617 WDV 625
W +
Sbjct: 207 WAI 209
>BC098443-1|AAH98443.1| 504|Homo sapiens cholinergic receptor,
nicotinic, alpha 3 protein.
Length = 504
Score = 69.7 bits (163), Expect = 1e-11
Identities = 36/123 (29%), Positives = 63/123 (51%), Gaps = 5/123 (4%)
Frame = +2
Query: 272 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 445
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 86 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 145
Query: 446 VSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDXMDFVI---DKRIYSMFESGA 616
V+WI + + + +P D Q CT KFGS ++ +D V+ + +ESG
Sbjct: 146 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVLIGSSMNLKDYWESGE 205
Query: 617 WDV 625
W +
Sbjct: 206 WAI 208
>BC006114-1|AAH06114.1| 489|Homo sapiens CHRNA3 protein protein.
Length = 489
Score = 69.7 bits (163), Expect = 1e-11
Identities = 36/123 (29%), Positives = 63/123 (51%), Gaps = 5/123 (4%)
Frame = +2
Query: 272 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 445
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 87 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 146
Query: 446 VSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDXMDFVI---DKRIYSMFESGA 616
V+WI + + + +P D Q CT KFGS ++ +D V+ + +ESG
Sbjct: 147 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVLIGSSMNLKDYWESGE 206
Query: 617 WDV 625
W +
Sbjct: 207 WAI 209
>BC002996-1|AAH02996.1| 505|Homo sapiens cholinergic receptor,
nicotinic, alpha 3 protein.
Length = 505
Score = 69.7 bits (163), Expect = 1e-11
Identities = 36/123 (29%), Positives = 63/123 (51%), Gaps = 5/123 (4%)
Frame = +2
Query: 272 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 445
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 87 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 146
Query: 446 VSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDXMDFVI---DKRIYSMFESGA 616
V+WI + + + +P D Q CT KFGS ++ +D V+ + +ESG
Sbjct: 147 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVLIGSSMNLKDYWESGE 206
Query: 617 WDV 625
W +
Sbjct: 207 WAI 209
>BC001642-1|AAH01642.1| 505|Homo sapiens cholinergic receptor,
nicotinic, alpha 3 protein.
Length = 505
Score = 69.7 bits (163), Expect = 1e-11
Identities = 36/123 (29%), Positives = 63/123 (51%), Gaps = 5/123 (4%)
Frame = +2
Query: 272 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 445
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 87 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 146
Query: 446 VSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDXMDFVI---DKRIYSMFESGA 616
V+WI + + + +P D Q CT KFGS ++ +D V+ + +ESG
Sbjct: 147 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVLIGSSMNLKDYWESGE 206
Query: 617 WDV 625
W +
Sbjct: 207 WAI 209
>BC000513-1|AAH00513.1| 505|Homo sapiens cholinergic receptor,
nicotinic, alpha 3 protein.
Length = 505
Score = 69.7 bits (163), Expect = 1e-11
Identities = 36/123 (29%), Positives = 63/123 (51%), Gaps = 5/123 (4%)
Frame = +2
Query: 272 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 445
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 87 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 146
Query: 446 VSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDXMDFVI---DKRIYSMFESGA 616
V+WI + + + +P D Q CT KFGS ++ +D V+ + +ESG
Sbjct: 147 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVLIGSSMNLKDYWESGE 206
Query: 617 WDV 625
W +
Sbjct: 207 WAI 209
>AJ007783-1|CAA07682.1| 504|Homo sapiens nicotinic acetylcholine
receptor alpha-3 subunit protein.
Length = 504
Score = 69.7 bits (163), Expect = 1e-11
Identities = 36/123 (29%), Positives = 63/123 (51%), Gaps = 5/123 (4%)
Frame = +2
Query: 272 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 445
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 86 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 145
Query: 446 VSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDXMDFVI---DKRIYSMFESGA 616
V+WI + + + +P D Q CT KFGS ++ +D V+ + +ESG
Sbjct: 146 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVLIGSSMNLKDYWESGE 205
Query: 617 WDV 625
W +
Sbjct: 206 WAI 208
>AF385584-1|AAK68110.1| 489|Homo sapiens nicotinic cholinergic
receptor alpha 3 protein.
Length = 489
Score = 69.7 bits (163), Expect = 1e-11
Identities = 36/123 (29%), Positives = 63/123 (51%), Gaps = 5/123 (4%)
Frame = +2
Query: 272 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 445
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 81 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 140
Query: 446 VSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDXMDFVI---DKRIYSMFESGA 616
V+WI + + + +P D Q CT KFGS ++ +D V+ + +ESG
Sbjct: 141 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVLIGSSMNLKDYWESGE 200
Query: 617 WDV 625
W +
Sbjct: 201 WAI 203
>Y08421-1|CAA69698.1| 627|Homo sapiens nicotinic acetylcholine
receptor alpha4 subunit precursor protein.
Length = 627
Score = 69.3 bits (162), Expect = 2e-11
Identities = 50/177 (28%), Positives = 89/177 (50%), Gaps = 13/177 (7%)
Frame = +2
Query: 140 MIDSLLATYDRESPPDSKI--VVNLTLHLRHASIRESESTVRMLAG---LQMNWIDKRLS 304
++ L + Y++ S P + I VV + L A + + + +M+ ++ W D +L
Sbjct: 40 LLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLR 99
Query: 305 WNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNGSVSWIKRLD 469
W+ ++ T + + SE +WRPD+VL N A GD+A+ +A + ++G V W
Sbjct: 100 WDPADYENVTSIRIPSELIWRPDIVLYNNAD---GDFAVTHLTKAHLFHDGRVQWTPPAI 156
Query: 470 ISTPISMQLDNWPNDMQTCTFKFGSRMHNSDXMDFV-IDKRI--YSMFESGAWDVTD 631
+ S+ + +P D Q CT KFGS ++ +D V + R+ +ESG W + D
Sbjct: 157 YKSSCSIDVTFFPFDQQNCTMKFGSWTYDKAKIDLVNMHSRVDQLDFWESGEWVIVD 213
>X89741-1|CAA61893.1| 627|Homo sapiens neuronal acetylcholine
receptor alpha-4 subunit protein.
Length = 627
Score = 69.3 bits (162), Expect = 2e-11
Identities = 50/177 (28%), Positives = 89/177 (50%), Gaps = 13/177 (7%)
Frame = +2
Query: 140 MIDSLLATYDRESPPDSKI--VVNLTLHLRHASIRESESTVRMLAG---LQMNWIDKRLS 304
++ L + Y++ S P + I VV + L A + + + +M+ ++ W D +L
Sbjct: 40 LLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLR 99
Query: 305 WNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNGSVSWIKRLD 469
W+ ++ T + + SE +WRPD+VL N A GD+A+ +A + ++G V W
Sbjct: 100 WDPADYENVTSIRIPSELIWRPDIVLYNNAD---GDFAVTHLTKAHLFHDGRVQWTPPAI 156
Query: 470 ISTPISMQLDNWPNDMQTCTFKFGSRMHNSDXMDFV-IDKRI--YSMFESGAWDVTD 631
+ S+ + +P D Q CT KFGS ++ +D V + R+ +ESG W + D
Sbjct: 157 YKSSCSIDVTFFPFDQQNCTMKFGSWTYDKAKIDLVNMHSRVDQLDFWESGEWVIVD 213
>X87629-1|CAA60959.1| 602|Homo sapiens nicotinic acetylcholine
receptor protein.
Length = 602
Score = 69.3 bits (162), Expect = 2e-11
Identities = 50/177 (28%), Positives = 89/177 (50%), Gaps = 13/177 (7%)
Frame = +2
Query: 140 MIDSLLATYDRESPPDSKI--VVNLTLHLRHASIRESESTVRMLAG---LQMNWIDKRLS 304
++ L + Y++ S P + I VV + L A + + + +M+ ++ W D +L
Sbjct: 15 LLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLR 74
Query: 305 WNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNGSVSWIKRLD 469
W+ ++ T + + SE +WRPD+VL N A GD+A+ +A + ++G V W
Sbjct: 75 WDPADYENVTSIRIPSELIWRPDIVLYNNAD---GDFAVTHLTKAHLFHDGRVQWTPPAI 131
Query: 470 ISTPISMQLDNWPNDMQTCTFKFGSRMHNSDXMDFV-IDKRI--YSMFESGAWDVTD 631
+ S+ + +P D Q CT KFGS ++ +D V + R+ +ESG W + D
Sbjct: 132 YKSSCSIDVTFFPFDQQNCTMKFGSWTYDKAKIDLVNMHSRVDQLDFWESGEWVIVD 188
>U62433-1|AAB40111.1| 627|Homo sapiens nicotinic acetylcholine
receptor alpha4 subunit precursor protein.
Length = 627
Score = 69.3 bits (162), Expect = 2e-11
Identities = 50/177 (28%), Positives = 89/177 (50%), Gaps = 13/177 (7%)
Frame = +2
Query: 140 MIDSLLATYDRESPPDSKI--VVNLTLHLRHASIRESESTVRMLAG---LQMNWIDKRLS 304
++ L + Y++ S P + I VV + L A + + + +M+ ++ W D +L
Sbjct: 40 LLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLR 99
Query: 305 WNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNGSVSWIKRLD 469
W+ ++ T + + SE +WRPD+VL N A GD+A+ +A + ++G V W
Sbjct: 100 WDPADYENVTSIRIPSELIWRPDIVLYNNAD---GDFAVTHLTKAHLFHDGRVQWTPPAI 156
Query: 470 ISTPISMQLDNWPNDMQTCTFKFGSRMHNSDXMDFV-IDKRI--YSMFESGAWDVTD 631
+ S+ + +P D Q CT KFGS ++ +D V + R+ +ESG W + D
Sbjct: 157 YKSSCSIDVTFFPFDQQNCTMKFGSWTYDKAKIDLVNMHSRVDQLDFWESGEWVIVD 213
>L35901-1|AAA64743.1| 627|Homo sapiens nicotinic acetylcholine
receptor alpha 4 subunit protein.
Length = 627
Score = 69.3 bits (162), Expect = 2e-11
Identities = 50/177 (28%), Positives = 89/177 (50%), Gaps = 13/177 (7%)
Frame = +2
Query: 140 MIDSLLATYDRESPPDSKI--VVNLTLHLRHASIRESESTVRMLAG---LQMNWIDKRLS 304
++ L + Y++ S P + I VV + L A + + + +M+ ++ W D +L
Sbjct: 40 LLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLR 99
Query: 305 WNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNGSVSWIKRLD 469
W+ ++ T + + SE +WRPD+VL N A GD+A+ +A + ++G V W
Sbjct: 100 WDPADYENVTSIRIPSELIWRPDIVLYNNAD---GDFAVTHLTKAHLFHDGRVQWTPPAI 156
Query: 470 ISTPISMQLDNWPNDMQTCTFKFGSRMHNSDXMDFV-IDKRI--YSMFESGAWDVTD 631
+ S+ + +P D Q CT KFGS ++ +D V + R+ +ESG W + D
Sbjct: 157 YKSSCSIDVTFFPFDQQNCTMKFGSWTYDKAKIDLVNMHSRVDQLDFWESGEWVIVD 213
>DQ093071-1|AAY88737.1| 627|Homo sapiens cholinergic receptor,
nicotinic, alpha polypeptide 4 protein.
Length = 627
Score = 69.3 bits (162), Expect = 2e-11
Identities = 50/177 (28%), Positives = 89/177 (50%), Gaps = 13/177 (7%)
Frame = +2
Query: 140 MIDSLLATYDRESPPDSKI--VVNLTLHLRHASIRESESTVRMLAG---LQMNWIDKRLS 304
++ L + Y++ S P + I VV + L A + + + +M+ ++ W D +L
Sbjct: 40 LLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLR 99
Query: 305 WNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNGSVSWIKRLD 469
W+ ++ T + + SE +WRPD+VL N A GD+A+ +A + ++G V W
Sbjct: 100 WDPADYENVTSIRIPSELIWRPDIVLYNNAD---GDFAVTHLTKAHLFHDGRVQWTPPAI 156
Query: 470 ISTPISMQLDNWPNDMQTCTFKFGSRMHNSDXMDFV-IDKRI--YSMFESGAWDVTD 631
+ S+ + +P D Q CT KFGS ++ +D V + R+ +ESG W + D
Sbjct: 157 YKSSCSIDVTFFPFDQQNCTMKFGSWTYDKAKIDLVNMHSRVDQLDFWESGEWVIVD 213
>BC096290-1|AAH96290.1| 627|Homo sapiens cholinergic receptor,
nicotinic, alpha 4 protein.
Length = 627
Score = 69.3 bits (162), Expect = 2e-11
Identities = 50/177 (28%), Positives = 89/177 (50%), Gaps = 13/177 (7%)
Frame = +2
Query: 140 MIDSLLATYDRESPPDSKI--VVNLTLHLRHASIRESESTVRMLAG---LQMNWIDKRLS 304
++ L + Y++ S P + I VV + L A + + + +M+ ++ W D +L
Sbjct: 40 LLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLR 99
Query: 305 WNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNGSVSWIKRLD 469
W+ ++ T + + SE +WRPD+VL N A GD+A+ +A + ++G V W
Sbjct: 100 WDPADYENVTSIRIPSELIWRPDIVLYNNAD---GDFAVTHLTKAHLFHDGRVQWTPPAI 156
Query: 470 ISTPISMQLDNWPNDMQTCTFKFGSRMHNSDXMDFV-IDKRI--YSMFESGAWDVTD 631
+ S+ + +P D Q CT KFGS ++ +D V + R+ +ESG W + D
Sbjct: 157 YKSSCSIDVTFFPFDQQNCTMKFGSWTYDKAKIDLVNMHSRVDQLDFWESGEWVIVD 213
>Y08415-1|CAA69692.1| 502|Homo sapiens nicotinic acetylcholine
receptor beta2 subunit precursor protein.
Length = 502
Score = 68.5 bits (160), Expect = 3e-11
Identities = 44/153 (28%), Positives = 71/153 (46%), Gaps = 6/153 (3%)
Frame = +2
Query: 194 IVVNLTLHLRHA-SIRESESTVRMLAGLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 367
+ V L + L S+ E E + L W D RL+W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 368 DVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 544
DVVL N A + A VS +GS+ W+ + +++ ++P D Q CT KF S
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRS 175
Query: 545 RMHNSDXMDFVIDKRIYSMFE---SGAWDVTDL 634
++ +D V+ + S+ + SG WD+ L
Sbjct: 176 WTYDRTEIDLVLKSEVASLDDFTPSGEWDIVAL 208
>X53179-1|CAA37320.1| 502|Homo sapiens precursor peptide (AA -25 to
477) protein.
Length = 502
Score = 68.5 bits (160), Expect = 3e-11
Identities = 44/153 (28%), Positives = 71/153 (46%), Gaps = 6/153 (3%)
Frame = +2
Query: 194 IVVNLTLHLRHA-SIRESESTVRMLAGLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 367
+ V L + L S+ E E + L W D RL+W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 368 DVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 544
DVVL N A + A VS +GS+ W+ + +++ ++P D Q CT KF S
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRS 175
Query: 545 RMHNSDXMDFVIDKRIYSMFE---SGAWDVTDL 634
++ +D V+ + S+ + SG WD+ L
Sbjct: 176 WTYDRTEIDLVLKSEVASLDDFTPSGEWDIVAL 208
>U62437-1|AAB40115.1| 502|Homo sapiens nicotinic acetylcholine
receptor beta2 subunit precursor protein.
Length = 502
Score = 68.5 bits (160), Expect = 3e-11
Identities = 44/153 (28%), Positives = 71/153 (46%), Gaps = 6/153 (3%)
Frame = +2
Query: 194 IVVNLTLHLRHA-SIRESESTVRMLAGLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 367
+ V L + L S+ E E + L W D RL+W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 368 DVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 544
DVVL N A + A VS +GS+ W+ + +++ ++P D Q CT KF S
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRS 175
Query: 545 RMHNSDXMDFVIDKRIYSMFE---SGAWDVTDL 634
++ +D V+ + S+ + SG WD+ L
Sbjct: 176 WTYDRTEIDLVLKSEVASLDDFTPSGEWDIVAL 208
>BC075041-1|AAH75041.1| 502|Homo sapiens cholinergic receptor,
nicotinic, beta 2 (neuronal) protein.
Length = 502
Score = 68.5 bits (160), Expect = 3e-11
Identities = 44/153 (28%), Positives = 71/153 (46%), Gaps = 6/153 (3%)
Frame = +2
Query: 194 IVVNLTLHLRHA-SIRESESTVRMLAGLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 367
+ V L + L S+ E E + L W D RL+W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 368 DVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 544
DVVL N A + A VS +GS+ W+ + +++ ++P D Q CT KF S
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRS 175
Query: 545 RMHNSDXMDFVIDKRIYSMFE---SGAWDVTDL 634
++ +D V+ + S+ + SG WD+ L
Sbjct: 176 WTYDRTEIDLVLKSEVASLDDFTPSGEWDIVAL 208
>BC075040-1|AAH75040.1| 502|Homo sapiens cholinergic receptor,
nicotinic, beta 2 (neuronal) protein.
Length = 502
Score = 68.5 bits (160), Expect = 3e-11
Identities = 44/153 (28%), Positives = 71/153 (46%), Gaps = 6/153 (3%)
Frame = +2
Query: 194 IVVNLTLHLRHA-SIRESESTVRMLAGLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 367
+ V L + L S+ E E + L W D RL+W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 368 DVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 544
DVVL N A + A VS +GS+ W+ + +++ ++P D Q CT KF S
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRS 175
Query: 545 RMHNSDXMDFVIDKRIYSMFE---SGAWDVTDL 634
++ +D V+ + S+ + SG WD+ L
Sbjct: 176 WTYDRTEIDLVLKSEVASLDDFTPSGEWDIVAL 208
>AL592078-3|CAI16184.1| 502|Homo sapiens cholinergic receptor,
nicotinic, beta 2 (neuronal) protein.
Length = 502
Score = 68.5 bits (160), Expect = 3e-11
Identities = 44/153 (28%), Positives = 71/153 (46%), Gaps = 6/153 (3%)
Frame = +2
Query: 194 IVVNLTLHLRHA-SIRESESTVRMLAGLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 367
+ V L + L S+ E E + L W D RL+W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 368 DVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 544
DVVL N A + A VS +GS+ W+ + +++ ++P D Q CT KF S
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRS 175
Query: 545 RMHNSDXMDFVIDKRIYSMFE---SGAWDVTDL 634
++ +D V+ + S+ + SG WD+ L
Sbjct: 176 WTYDRTEIDLVLKSEVASLDDFTPSGEWDIVAL 208
>AJ001935-1|CAA05108.1| 504|Homo sapiens CHRNB2 protein.
Length = 504
Score = 68.5 bits (160), Expect = 3e-11
Identities = 44/153 (28%), Positives = 71/153 (46%), Gaps = 6/153 (3%)
Frame = +2
Query: 194 IVVNLTLHLRHA-SIRESESTVRMLAGLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 367
+ V L + L S+ E E + L W D RL+W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 368 DVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 544
DVVL N A + A VS +GS+ W+ + +++ ++P D Q CT KF S
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRS 175
Query: 545 RMHNSDXMDFVIDKRIYSMFE---SGAWDVTDL 634
++ +D V+ + S+ + SG WD+ L
Sbjct: 176 WTYDRTEIDLVLKSEVASLDDFTPSGEWDIVAL 208
>AF077186-1|AAD45422.1| 502|Homo sapiens neuronal nicotinic
acetylcholine receptor beta 2 protein.
Length = 502
Score = 68.5 bits (160), Expect = 3e-11
Identities = 44/153 (28%), Positives = 71/153 (46%), Gaps = 6/153 (3%)
Frame = +2
Query: 194 IVVNLTLHLRHA-SIRESESTVRMLAGLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 367
+ V L + L S+ E E + L W D RL+W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 368 DVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 544
DVVL N A + A VS +GS+ W+ + +++ ++P D Q CT KF S
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRS 175
Query: 545 RMHNSDXMDFVIDKRIYSMFE---SGAWDVTDL 634
++ +D V+ + S+ + SG WD+ L
Sbjct: 176 WTYDRTEIDLVLKSEVASLDDFTPSGEWDIVAL 208
>Y16281-1|CAA76154.1| 529|Homo sapiens nicotinic acetylcholine
receptor alpha2 subunit precursor protein.
Length = 529
Score = 67.7 bits (158), Expect = 5e-11
Identities = 46/160 (28%), Positives = 79/160 (49%), Gaps = 10/160 (6%)
Frame = +2
Query: 182 PDSKIVVNLTLHLRHASIRESESTVRMLAG---LQMNWIDKRLSWNAGEWGCSTWL-VSS 349
P++ VV + L A + + + +M+ L+ W D +L WN ++G T L V S
Sbjct: 78 PNTSDVVIVRFGLSIAQLIDVDEKNQMMTTNVWLKQEWSDYKLRWNPADFGNITSLRVPS 137
Query: 350 ERLWRPDVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTC 526
E +W PD+VL N A A + +A + + G+V W+ + S+ + +P D Q C
Sbjct: 138 EMIWIPDIVLYNNADGEFAVTHMTKAHLFSTGTVHWVPPAIYKSSCSIDVTFFPFDQQNC 197
Query: 527 TFKFGSRMHNS-----DXMDFVIDKRIYSMFESGAWDVTD 631
KFGS ++ + M+ +D + Y +ESG W + +
Sbjct: 198 KMKFGSWTYDKAKIDLEQMEQTVDLKDY--WESGEWAIVN 235
>U62431-1|AAB40109.1| 529|Homo sapiens nicotinic acetylcholine
receptor alpha2 subunit precursor protein.
Length = 529
Score = 67.7 bits (158), Expect = 5e-11
Identities = 46/160 (28%), Positives = 79/160 (49%), Gaps = 10/160 (6%)
Frame = +2
Query: 182 PDSKIVVNLTLHLRHASIRESESTVRMLAG---LQMNWIDKRLSWNAGEWGCSTWL-VSS 349
P++ VV + L A + + + +M+ L+ W D +L WN ++G T L V S
Sbjct: 78 PNTSDVVIVRFGLSIAQLIDVDEKNQMMTTNVWLKQEWSDYKLRWNPADFGNITSLRVPS 137
Query: 350 ERLWRPDVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTC 526
E +W PD+VL N A A + +A + + G+V W+ + S+ + +P D Q C
Sbjct: 138 EMIWIPDIVLYNNADGEFAVTHMTKAHLFSTGTVHWVPPAIYKSSCSIDVTFFPFDQQNC 197
Query: 527 TFKFGSRMHNS-----DXMDFVIDKRIYSMFESGAWDVTD 631
KFGS ++ + M+ +D + Y +ESG W + +
Sbjct: 198 KMKFGSWTYDKAKIDLEQMEQTVDLKDY--WESGEWAIVN 235
>M86383-1|AAC84176.1| 502|Homo sapiens nicotinic acetylcholine
receptor alpha 3 subunit precursor protein.
Length = 502
Score = 67.3 bits (157), Expect = 7e-11
Identities = 37/126 (29%), Positives = 65/126 (51%), Gaps = 8/126 (6%)
Frame = +2
Query: 272 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYAL----RARVSN 436
L+ W D +L WN +G + ++ V ++++W+PD+VL N A GD+ + +A +
Sbjct: 84 LKQIWNDYKLKWNPSGYGGAEFMRVPAQKIWKPDIVLYNNAV---GDFQVTTKTKALLKY 140
Query: 437 NGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDXMDFVI---DKRIYSMFE 607
G V+WI + + + +P D Q CT KFGS ++ +D V+ + +E
Sbjct: 141 TGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVLIGSSMNLKDYWE 200
Query: 608 SGAWDV 625
SG W +
Sbjct: 201 SGEWAI 206
>Y16282-1|CAA76155.1| 494|Homo sapiens nicotinic acetylcholine
receptor alpha6 subunit precursor protein.
Length = 494
Score = 66.1 bits (154), Expect = 2e-10
Identities = 45/188 (23%), Positives = 87/188 (46%), Gaps = 13/188 (6%)
Frame = +2
Query: 113 CENATSLSLMIDSLLATYDRESPPDSKIVVNLTLHL-----RHASIRESESTVRMLAGLQ 277
C + + L + Y++ P + +T+H + A++ E + L+
Sbjct: 28 CVGCATEERLFHKLFSHYNQFIRPVENVSDPVTVHFEVAITQLANVDEVNQIMETNLWLR 87
Query: 278 MNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNG 442
W D +L W+ E+ G T V ++++W+PD+VL N A GD+ + +A + NG
Sbjct: 88 HIWNDYKLRWDPMEYDGIETLRVPADKIWKPDIVLYNNAV---GDFQVEGKTKALLKYNG 144
Query: 443 SVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDXMD-FVIDKRI--YSMFESG 613
++W + M + +P D Q C+ KFGS ++ +D +I ++ +E+
Sbjct: 145 MITWTPPAIFKSSCPMDITFFPFDHQNCSLKFGSWTYDKAEIDLLIIGSKVDMNDFWENS 204
Query: 614 AWDVTDLS 637
W++ D S
Sbjct: 205 EWEIIDAS 212
>U62435-1|AAB40113.1| 494|Homo sapiens nicotinic acetylcholine
receptor alpha6 subunit precursor protein.
Length = 494
Score = 66.1 bits (154), Expect = 2e-10
Identities = 45/188 (23%), Positives = 87/188 (46%), Gaps = 13/188 (6%)
Frame = +2
Query: 113 CENATSLSLMIDSLLATYDRESPPDSKIVVNLTLHL-----RHASIRESESTVRMLAGLQ 277
C + + L + Y++ P + +T+H + A++ E + L+
Sbjct: 28 CVGCATEERLFHKLFSHYNQFIRPVENVSDPVTVHFEVAITQLANVDEVNQIMETNLWLR 87
Query: 278 MNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNG 442
W D +L W+ E+ G T V ++++W+PD+VL N A GD+ + +A + NG
Sbjct: 88 HIWNDYKLRWDPMEYDGIETLRVPADKIWKPDIVLYNNAV---GDFQVEGKTKALLKYNG 144
Query: 443 SVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDXMD-FVIDKRI--YSMFESG 613
++W + M + +P D Q C+ KFGS ++ +D +I ++ +E+
Sbjct: 145 MITWTPPAIFKSSCPMDITFFPFDHQNCSLKFGSWTYDKAEIDLLIIGSKVDMNDFWENS 204
Query: 614 AWDVTDLS 637
W++ D S
Sbjct: 205 EWEIIDAS 212
>BC014456-1|AAH14456.1| 494|Homo sapiens cholinergic receptor,
nicotinic, alpha 6 protein.
Length = 494
Score = 66.1 bits (154), Expect = 2e-10
Identities = 45/188 (23%), Positives = 87/188 (46%), Gaps = 13/188 (6%)
Frame = +2
Query: 113 CENATSLSLMIDSLLATYDRESPPDSKIVVNLTLHL-----RHASIRESESTVRMLAGLQ 277
C + + L + Y++ P + +T+H + A++ E + L+
Sbjct: 28 CVGCATEERLFHKLFSHYNQFIRPVENVSDPVTVHFEVAITQLANVDEVNQIMETNLWLR 87
Query: 278 MNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNG 442
W D +L W+ E+ G T V ++++W+PD+VL N A GD+ + +A + NG
Sbjct: 88 HIWNDYKLRWDPMEYDGIETLRVPADKIWKPDIVLYNNAV---GDFQVEGKTKALLKYNG 144
Query: 443 SVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDXMD-FVIDKRI--YSMFESG 613
++W + M + +P D Q C+ KFGS ++ +D +I ++ +E+
Sbjct: 145 MITWTPPAIFKSSCPMDITFFPFDHQNCSLKFGSWTYDKAEIDLLIIGSKVDMNDFWENS 204
Query: 614 AWDVTDLS 637
W++ D S
Sbjct: 205 EWEIIDAS 212
>AB079251-1|BAC06855.1| 494|Homo sapiens Nicotinic acetylcholine
receptor alpha 6 protein.
Length = 494
Score = 66.1 bits (154), Expect = 2e-10
Identities = 45/188 (23%), Positives = 87/188 (46%), Gaps = 13/188 (6%)
Frame = +2
Query: 113 CENATSLSLMIDSLLATYDRESPPDSKIVVNLTLHL-----RHASIRESESTVRMLAGLQ 277
C + + L + Y++ P + +T+H + A++ E + L+
Sbjct: 28 CVGCATEERLFHKLFSHYNQFIRPVENVSDPVTVHFEVAITQLANVDEVNQIMETNLWLR 87
Query: 278 MNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNG 442
W D +L W+ E+ G T V ++++W+PD+VL N A GD+ + +A + NG
Sbjct: 88 HIWNDYKLRWDPMEYDGIETLRVPADKIWKPDIVLYNNAV---GDFQVEGKTKALLKYNG 144
Query: 443 SVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDXMD-FVIDKRI--YSMFESG 613
++W + M + +P D Q C+ KFGS ++ +D +I ++ +E+
Sbjct: 145 MITWTPPAIFKSSCPMDITFFPFDHQNCSLKFGSWTYDKAEIDLLIIGSKVDMNDFWENS 204
Query: 614 AWDVTDLS 637
W++ D S
Sbjct: 205 EWEIIDAS 212
>X66403-1|CAA47030.1| 493|Homo sapiens acetylcholine receptor
epsilon subunit CHRNE protein.
Length = 493
Score = 62.9 bits (146), Expect = 1e-09
Identities = 36/134 (26%), Positives = 70/134 (52%), Gaps = 3/134 (2%)
Frame = +2
Query: 182 PDSKIVVNLTLHLRHA-SIRESESTVRMLAGLQMNWIDKRLSWNAGEWG-CSTWLVSSER 355
P+ + ++L + L + S+ E E T+ + ++W D RL+++ ++G T V SE
Sbjct: 45 PEDTVTISLKVTLTNLISLNEKEETLTTSVWIGIDWQDYRLNYSKDDFGGIETLRVPSEL 104
Query: 356 LWRPDVVLLNAAATTAG-DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTF 532
+W P++VL N G Y V GSV+W+ + ++++ +P D Q C+
Sbjct: 105 VWLPEIVLENNIDGQFGVAYDANVLVYEGGSVTWLPPAIYRSVCAVEVTYFPFDWQNCSL 164
Query: 533 KFGSRMHNSDXMDF 574
F S+ +N++ ++F
Sbjct: 165 IFRSQTYNAEEVEF 178
>AF105999-1|AAD24503.1| 493|Homo sapiens acetylcholine receptor
epsilon subunit protein.
Length = 493
Score = 62.9 bits (146), Expect = 1e-09
Identities = 36/134 (26%), Positives = 70/134 (52%), Gaps = 3/134 (2%)
Frame = +2
Query: 182 PDSKIVVNLTLHLRHA-SIRESESTVRMLAGLQMNWIDKRLSWNAGEWG-CSTWLVSSER 355
P+ + ++L + L + S+ E E T+ + ++W D RL+++ ++G T V SE
Sbjct: 45 PEDTVTISLKVTLTNLISLNEKEETLTTSVWIGIDWQDYRLNYSKDDFGGIETLRVPSEL 104
Query: 356 LWRPDVVLLNAAATTAG-DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTF 532
+W P++VL N G Y V GSV+W+ + ++++ +P D Q C+
Sbjct: 105 VWLPEIVLENNIDGQFGVAYDANVLVYEGGSVTWLPPAIYRSVCAVEVTYFPFDWQNCSL 164
Query: 533 KFGSRMHNSDXMDF 574
F S+ +N++ ++F
Sbjct: 165 IFRSQTYNAEEVEF 178
>BC131799-1|AAI31800.1| 447|Homo sapiens 5-hydroxytryptamine
(serotonin) receptor 3, family member C protein.
Length = 447
Score = 62.1 bits (144), Expect = 3e-09
Identities = 36/136 (26%), Positives = 65/136 (47%), Gaps = 1/136 (0%)
Frame = +2
Query: 272 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 448
+ + W + ++WN E G + V +E LW PD+ ++ + L A +S+ G +
Sbjct: 91 MDLVWDNPFINWNPKECVGINKLTVLAENLWLPDIFIVESMDVDQTPSGLTAYISSEGRI 150
Query: 449 SWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDXMDFVIDKRIYSMFESGAWDVT 628
+ K + +++ ++ + +P D Q CTF F S ++ D M +DK + W++T
Sbjct: 151 KYDKPMRVTSICNLDIFYFPFDQQNCTFTFSSFLYTVDSMLLGMDKEV--------WEIT 202
Query: 629 DLSSAVXXQXVARWXL 676
D S V Q W L
Sbjct: 203 DTSRKV-IQTQGEWEL 217
>AF459285-1|AAL66182.1| 447|Homo sapiens 5-hydroxytryptamine
receptor 3 subunit C protein.
Length = 447
Score = 61.7 bits (143), Expect = 3e-09
Identities = 36/136 (26%), Positives = 64/136 (47%), Gaps = 1/136 (0%)
Frame = +2
Query: 272 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 448
+ + W + ++WN E G + V +E LW PD+ ++ + L A +S+ G +
Sbjct: 91 MDLVWDNPFINWNPKECVGINKLTVLAENLWLPDIFIVESMDVDQTPSGLTAYISSEGRI 150
Query: 449 SWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDXMDFVIDKRIYSMFESGAWDVT 628
+ K + +++ + + +P D Q CTF F S ++ D M +DK + W++T
Sbjct: 151 KYDKPMRVTSICKLDIFYFPFDQQNCTFTFSSFLYTVDSMLLGMDKEV--------WEIT 202
Query: 629 DLSSAVXXQXVARWXL 676
D S V Q W L
Sbjct: 203 DTSRKV-IQTQGEWEL 217
>DQ644022-1|ABG35128.1| 456|Homo sapiens 5-HT3 receptor subunit E
splice variant HTR3Ea protein.
Length = 456
Score = 60.9 bits (141), Expect = 6e-09
Identities = 34/133 (25%), Positives = 65/133 (48%), Gaps = 9/133 (6%)
Frame = +2
Query: 272 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 448
L+M W + +SWN E G + ++++ LW PD+ ++ L A VSN G +
Sbjct: 91 LEMVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEGRI 150
Query: 449 SWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDXMDFVIDKRIYSMFES------ 610
+ K + + + ++ + +P D Q CT F S ++ D M ++K ++ + ++
Sbjct: 151 RYKKPMKVDSICNLDIFYFPFDQQNCTLTFSSFLYTVDSMLLDMEKEVWEITDASRNILQ 210
Query: 611 --GAWDVTDLSSA 643
G W++ LS A
Sbjct: 211 THGEWELLGLSKA 223
>BC101185-1|AAI01186.1| 374|Homo sapiens HTR3E protein protein.
Length = 374
Score = 60.9 bits (141), Expect = 6e-09
Identities = 34/133 (25%), Positives = 65/133 (48%), Gaps = 9/133 (6%)
Frame = +2
Query: 272 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 448
L+M W + +SWN E G + ++++ LW PD+ ++ L A VSN G +
Sbjct: 20 LEMVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEGRI 79
Query: 449 SWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDXMDFVIDKRIYSMFES------ 610
+ K + + + ++ + +P D Q CT F S ++ D M ++K ++ + ++
Sbjct: 80 RYKKPMKVDSICNLDIFYFPFDQQNCTLTFSSFLYTVDSMLLDMEKEVWEITDASRNILQ 139
Query: 611 --GAWDVTDLSSA 643
G W++ LS A
Sbjct: 140 THGEWELLGLSKA 152
>BC101183-1|AAI01184.1| 471|Homo sapiens 5-hydroxytryptamine
(serotonin) receptor 3, family member E protein.
Length = 471
Score = 60.9 bits (141), Expect = 6e-09
Identities = 34/133 (25%), Positives = 65/133 (48%), Gaps = 9/133 (6%)
Frame = +2
Query: 272 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 448
L+M W + +SWN E G + ++++ LW PD+ ++ L A VSN G +
Sbjct: 106 LEMVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEGRI 165
Query: 449 SWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDXMDFVIDKRIYSMFES------ 610
+ K + + + ++ + +P D Q CT F S ++ D M ++K ++ + ++
Sbjct: 166 RYKKPMKVDSICNLDIFYFPFDQQNCTLTFSSFLYTVDSMLLDMEKEVWEITDASRNILQ 225
Query: 611 --GAWDVTDLSSA 643
G W++ LS A
Sbjct: 226 THGEWELLGLSKA 238
>BC101182-1|AAI01183.1| 471|Homo sapiens 5-hydroxytryptamine
(serotonin) receptor 3, family member E protein.
Length = 471
Score = 60.9 bits (141), Expect = 6e-09
Identities = 34/133 (25%), Positives = 65/133 (48%), Gaps = 9/133 (6%)
Frame = +2
Query: 272 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 448
L+M W + +SWN E G + ++++ LW PD+ ++ L A VSN G +
Sbjct: 106 LEMVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEGRI 165
Query: 449 SWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDXMDFVIDKRIYSMFES------ 610
+ K + + + ++ + +P D Q CT F S ++ D M ++K ++ + ++
Sbjct: 166 RYKKPMKVDSICNLDIFYFPFDQQNCTLTFSSFLYTVDSMLLDMEKEVWEITDASRNILQ 225
Query: 611 --GAWDVTDLSSA 643
G W++ LS A
Sbjct: 226 THGEWELLGLSKA 238
>AY159813-1|AAO38167.2| 471|Homo sapiens 5-hydroxytryptamine
serotonin receptor 3E protein.
Length = 471
Score = 60.9 bits (141), Expect = 6e-09
Identities = 34/133 (25%), Positives = 65/133 (48%), Gaps = 9/133 (6%)
Frame = +2
Query: 272 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 448
L+M W + +SWN E G + ++++ LW PD+ ++ L A VSN G +
Sbjct: 106 LEMVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEGRI 165
Query: 449 SWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDXMDFVIDKRIYSMFES------ 610
+ K + + + ++ + +P D Q CT F S ++ D M ++K ++ + ++
Sbjct: 166 RYKKPMKVDSICNLDIFYFPFDQQNCTLTFSSFLYTVDSMLLDMEKEVWEITDASRNILQ 225
Query: 611 --GAWDVTDLSSA 643
G W++ LS A
Sbjct: 226 THGEWELLGLSKA 238
>X14830-1|CAA32939.1| 501|Homo sapiens protein ( Human mRNA for
muscle acetylcholine receptor beta-subunit. ).
Length = 501
Score = 60.5 bits (140), Expect = 8e-09
Identities = 39/113 (34%), Positives = 57/113 (50%), Gaps = 3/113 (2%)
Frame = +2
Query: 230 SIRESESTVRMLAGLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAG 406
S+ E + + L + W D RLSW+ E G + +++E +W PDVVLLN
Sbjct: 65 SLNEKDEEMSTKVYLDLEWTDYRLSWDPAEHDGIDSLRITAESVWLPDVVLLNNNDGNF- 123
Query: 407 DYAL--RARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNS 559
D AL VS++GSV W + S+Q+ +P D Q CT F S ++S
Sbjct: 124 DVALDISVVVSSDGSVRWQPPGIYRSSCSIQVTYFPFDWQNCTMVFSSYSYDS 176
>X01715-1|CAA25861.1| 520|Homo sapiens acetylcholine receptor gamma
chain precursor protein.
Length = 520
Score = 60.5 bits (140), Expect = 8e-09
Identities = 44/157 (28%), Positives = 77/157 (49%), Gaps = 8/157 (5%)
Frame = +2
Query: 140 MIDSLLATYD---RESPPDSKIV-VNLTLHLRHA-SIRESESTVRMLAGLQMNWIDKRLS 304
++ L+ YD R + DS +V V+L L L + S+ E E + ++M W D RL
Sbjct: 32 LLADLMQNYDPNLRPAERDSDVVNVSLKLTLTNLISLNEREEALTTNVWIEMQWCDYRLR 91
Query: 305 WNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARV--SNNGSVSWIKRLDIS 475
W+ ++ G V S +WRPD+VL N + AL V S +G + W+
Sbjct: 92 WDPRDYEGLWVLRVPSTMVWRPDIVLENNVDGVF-EVALYCNVLVSPDGCIYWLPPAIFR 150
Query: 476 TPISMQLDNWPNDMQTCTFKFGSRMHNSDXMDFVIDK 586
+ S+ + +P D Q C+ F S+ ++++ +D + +
Sbjct: 151 SACSISVTYFPFDWQNCSLIFQSQTYSTNEIDLQLSQ 187
>BC011371-1|AAH11371.1| 501|Homo sapiens cholinergic receptor,
nicotinic, beta 1 (muscle) protein.
Length = 501
Score = 60.5 bits (140), Expect = 8e-09
Identities = 39/113 (34%), Positives = 57/113 (50%), Gaps = 3/113 (2%)
Frame = +2
Query: 230 SIRESESTVRMLAGLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAG 406
S+ E + + L + W D RLSW+ E G + +++E +W PDVVLLN
Sbjct: 65 SLNEKDEEMSTKVYLDLEWTDYRLSWDPAEHDGIDSLRITAESVWLPDVVLLNNNDGNF- 123
Query: 407 DYAL--RARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNS 559
D AL VS++GSV W + S+Q+ +P D Q CT F S ++S
Sbjct: 124 DVALDISVVVSSDGSVRWQPPGIYRSSCSIQVTYFPFDWQNCTMVFSSYSYDS 176
>AC092165-3|AAY24103.1| 520|Homo sapiens unknown protein.
Length = 520
Score = 60.5 bits (140), Expect = 8e-09
Identities = 44/157 (28%), Positives = 77/157 (49%), Gaps = 8/157 (5%)
Frame = +2
Query: 140 MIDSLLATYD---RESPPDSKIV-VNLTLHLRHA-SIRESESTVRMLAGLQMNWIDKRLS 304
++ L+ YD R + DS +V V+L L L + S+ E E + ++M W D RL
Sbjct: 32 LLADLMQNYDPNLRPAERDSDVVNVSLKLTLTNLISLNEREEALTTNVWIEMQWCDYRLR 91
Query: 305 WNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARV--SNNGSVSWIKRLDIS 475
W+ ++ G V S +WRPD+VL N + AL V S +G + W+
Sbjct: 92 WDPRDYEGLWVLRVPSTMVWRPDIVLENNVDGVF-EVALYCNVLVSPDGCIYWLPPAIFR 150
Query: 476 TPISMQLDNWPNDMQTCTFKFGSRMHNSDXMDFVIDK 586
+ S+ + +P D Q C+ F S+ ++++ +D + +
Sbjct: 151 SACSISVTYFPFDWQNCSLIFQSQTYSTNEIDLQLSQ 187
>AY349353-1|AAQ93477.1| 456|Homo sapiens 5-HT3c1 serotonin
receptor-like protein protein.
Length = 456
Score = 59.7 bits (138), Expect = 1e-08
Identities = 35/137 (25%), Positives = 66/137 (48%), Gaps = 9/137 (6%)
Frame = +2
Query: 260 MLAGLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSN 436
M A L + W + +SWN E G + ++++ LW PD+ ++ L A VSN
Sbjct: 87 MSAILDVVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSN 146
Query: 437 NGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDXMDFVIDKRIYSMFES-- 610
G + + K + + + ++ + +P D Q CT F S ++ D M ++K ++ + ++
Sbjct: 147 EGRIRYKKPMKVDSICNLDIFYFPFDQQNCTLTFSSFLYTVDSMLLDMEKEVWEITDASR 206
Query: 611 ------GAWDVTDLSSA 643
G W++ LS A
Sbjct: 207 NILQTHGEWELLGLSKA 223
>AY349352-1|AAQ93476.1| 441|Homo sapiens 5-HT3c1 serotonin
receptor-like protein protein.
Length = 441
Score = 59.7 bits (138), Expect = 1e-08
Identities = 35/137 (25%), Positives = 66/137 (48%), Gaps = 9/137 (6%)
Frame = +2
Query: 260 MLAGLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSN 436
M A L + W + +SWN E G + ++++ LW PD+ ++ L A VSN
Sbjct: 72 MSAILDVVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSN 131
Query: 437 NGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDXMDFVIDKRIYSMFES-- 610
G + + K + + + ++ + +P D Q CT F S ++ D M ++K ++ + ++
Sbjct: 132 EGRIRYKKPMKVDSICNLDIFYFPFDQQNCTLTFSSFLYTVDSMLLDMEKEVWEITDASR 191
Query: 611 ------GAWDVTDLSSA 643
G W++ LS A
Sbjct: 192 NILQTHGEWELLGLSKA 208
>BC023553-1|AAH23553.1| 501|Homo sapiens cholinergic receptor,
nicotinic, beta 1 (muscle) protein.
Length = 501
Score = 59.3 bits (137), Expect = 2e-08
Identities = 37/115 (32%), Positives = 58/115 (50%), Gaps = 5/115 (4%)
Frame = +2
Query: 230 SIRESESTVRMLAGLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAG 406
S+ E + + L + W D RLSW+ E G + +++E +W PDVVLLN G
Sbjct: 65 SLNEKDEEMSTKVYLDLEWTDYRLSWDPAEHDGIDSLRITAESVWLPDVVLLN---NNDG 121
Query: 407 DY----ALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNS 559
++ + VS++GSV W + S+Q+ +P D Q CT F S ++S
Sbjct: 122 NFYVALDISVVVSSDGSVRWQPPGIYRSSCSIQVTYFPFDWQNCTMVFSSYSYDS 176
>BC113575-1|AAI13576.1| 479|Homo sapiens cholinergic receptor,
nicotinic, alpha 9 protein.
Length = 479
Score = 58.8 bits (136), Expect = 2e-08
Identities = 44/184 (23%), Positives = 83/184 (45%), Gaps = 10/184 (5%)
Frame = +2
Query: 104 AAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHASIRESESTVRMLAG-- 271
AAE + + + L Y P D+ V+N+TL + + I++ + ++L
Sbjct: 22 AAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQITLSQIKDMDERNQILTAYL 81
Query: 272 -LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGD-YALRARVSNNG 442
++ W D L+W+ ++ G + + S+ +WRPD+VL N A + + + +G
Sbjct: 82 WIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKADDESSEPVNTNVVLRYDG 141
Query: 443 SVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDXMDF--VIDKRIYSMF-ESG 613
++W + + + +P D Q C FGS +N + +D +D S F E
Sbjct: 142 LITWDAPAITKSSCVVDVTYFPFDNQQCNLTFGSWTYNGNQVDIFNALDSGDLSDFIEDV 201
Query: 614 AWDV 625
W+V
Sbjct: 202 EWEV 205
>BC113549-1|AAI13550.1| 479|Homo sapiens cholinergic receptor,
nicotinic, alpha 9 protein.
Length = 479
Score = 58.8 bits (136), Expect = 2e-08
Identities = 44/184 (23%), Positives = 83/184 (45%), Gaps = 10/184 (5%)
Frame = +2
Query: 104 AAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHASIRESESTVRMLAG-- 271
AAE + + + L Y P D+ V+N+TL + + I++ + ++L
Sbjct: 22 AAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQITLSQIKDMDERNQILTAYL 81
Query: 272 -LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGD-YALRARVSNNG 442
++ W D L+W+ ++ G + + S+ +WRPD+VL N A + + + +G
Sbjct: 82 WIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKADDESSEPVNTNVVLRYDG 141
Query: 443 SVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDXMDF--VIDKRIYSMF-ESG 613
++W + + + +P D Q C FGS +N + +D +D S F E
Sbjct: 142 LITWDAPAITKSSCVVDVTYFPFDNQQCNLTFGSWTYNGNQVDIFNALDSGDLSDFIEDV 201
Query: 614 AWDV 625
W+V
Sbjct: 202 EWEV 205
>AY123244-1|AAM74523.1| 479|Homo sapiens nicotinic acetylcholine
receptor subunit alpha 9 protein.
Length = 479
Score = 58.8 bits (136), Expect = 2e-08
Identities = 44/184 (23%), Positives = 83/184 (45%), Gaps = 10/184 (5%)
Frame = +2
Query: 104 AAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHASIRESESTVRMLAG-- 271
AAE + + + L Y P D+ V+N+TL + + I++ + ++L
Sbjct: 22 AAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQITLSQIKDMDERNQILTAYL 81
Query: 272 -LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGD-YALRARVSNNG 442
++ W D L+W+ ++ G + + S+ +WRPD+VL N A + + + +G
Sbjct: 82 WIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKADDESSEPVNTNVVLRYDG 141
Query: 443 SVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDXMDF--VIDKRIYSMF-ESG 613
++W + + + +P D Q C FGS +N + +D +D S F E
Sbjct: 142 LITWDAPAITKSSCVVDVTYFPFDNQQCNLTFGSWTYNGNQVDIFNALDSGDLSDFIEDV 201
Query: 614 AWDV 625
W+V
Sbjct: 202 EWEV 205
>AJ243342-1|CAB65091.1| 479|Homo sapiens nicotinic acetylcholine
receptor alpha 9 subunit protein.
Length = 479
Score = 58.8 bits (136), Expect = 2e-08
Identities = 44/184 (23%), Positives = 83/184 (45%), Gaps = 10/184 (5%)
Frame = +2
Query: 104 AAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHASIRESESTVRMLAG-- 271
AAE + + + L Y P D+ V+N+TL + + I++ + ++L
Sbjct: 22 AAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQITLSQIKDMDERNQILTAYL 81
Query: 272 -LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGD-YALRARVSNNG 442
++ W D L+W+ ++ G + + S+ +WRPD+VL N A + + + +G
Sbjct: 82 WIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKADDESSEPVNTNVVLRYDG 141
Query: 443 SVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDXMDF--VIDKRIYSMF-ESG 613
++W + + + +P D Q C FGS +N + +D +D S F E
Sbjct: 142 LITWDAPAITKSSCVVDVTYFPFDNQQCNLTFGSWTYNGNQVDIFNALDSGDLSDFIEDV 201
Query: 614 AWDV 625
W+V
Sbjct: 202 EWEV 205
>AF227732-1|AAF61920.1| 470|Homo sapiens nicotinic acetylcholine
receptor alpha 9 subunit protein.
Length = 470
Score = 58.8 bits (136), Expect = 2e-08
Identities = 44/184 (23%), Positives = 83/184 (45%), Gaps = 10/184 (5%)
Frame = +2
Query: 104 AAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHASIRESESTVRMLAG-- 271
AAE + + + L Y P D+ V+N+TL + + I++ + ++L
Sbjct: 16 AAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQITLSQIKDMDERNQILTAYL 75
Query: 272 -LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGD-YALRARVSNNG 442
++ W D L+W+ ++ G + + S+ +WRPD+VL N A + + + +G
Sbjct: 76 WIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKADDESSEPVNTNVVLRYDG 135
Query: 443 SVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDXMDF--VIDKRIYSMF-ESG 613
++W + + + +P D Q C FGS +N + +D +D S F E
Sbjct: 136 LITWDAPAITKSSCVVDVTYFPFDNQQCNLTFGSWTYNGNQVDIFNALDSGDLSDFIEDV 195
Query: 614 AWDV 625
W+V
Sbjct: 196 EWEV 199
>AC118275-1|AAY40986.1| 479|Homo sapiens unknown protein.
Length = 479
Score = 58.8 bits (136), Expect = 2e-08
Identities = 44/184 (23%), Positives = 83/184 (45%), Gaps = 10/184 (5%)
Frame = +2
Query: 104 AAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHASIRESESTVRMLAG-- 271
AAE + + + L Y P D+ V+N+TL + + I++ + ++L
Sbjct: 22 AAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQITLSQIKDMDERNQILTAYL 81
Query: 272 -LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGD-YALRARVSNNG 442
++ W D L+W+ ++ G + + S+ +WRPD+VL N A + + + +G
Sbjct: 82 WIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKADDESSEPVNTNVVLRYDG 141
Query: 443 SVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDXMDF--VIDKRIYSMF-ESG 613
++W + + + +P D Q C FGS +N + +D +D S F E
Sbjct: 142 LITWDAPAITKSSCVVDVTYFPFDNQQCNLTFGSWTYNGNQVDIFNALDSGDLSDFIEDV 201
Query: 614 AWDV 625
W+V
Sbjct: 202 EWEV 205
>Y00762-1|CAA68731.1| 457|Homo sapiens protein ( Human mRNA for
muscle acetylcholine receptor alpha-subunit. ).
Length = 457
Score = 57.2 bits (132), Expect = 7e-08
Identities = 40/155 (25%), Positives = 74/155 (47%), Gaps = 8/155 (5%)
Frame = +2
Query: 191 KIVVNLTLHLRHASIRESESTVRMLAGLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRP 367
++ V L L ++ ++ E V L+ W+D L WN ++G + + SE++WRP
Sbjct: 50 EVTVGLQL-IQLINVDEVNQIVTTNVRLKQQWVDYNLKWNPDDYGGVKKIHIPSEKIWRP 108
Query: 368 DVVLLNAAATTAGDYAL----RARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFK 535
D+VL N A GD+A+ + + G ++W + + + ++P D Q C+ K
Sbjct: 109 DLVLYNNA---DGDFAIVKFTKVLLQYTGHITWTPPAIFKSYCEIIVTHFPFDEQNCSMK 165
Query: 536 FGSRMHNSDXMDF--VIDKRIYSMF-ESGAWDVTD 631
G+ ++ + D+ S F ESG W + +
Sbjct: 166 LGTWTYDGSVVAINPESDQPDLSNFMESGEWVIKE 200
>X02502-1|CAA26344.1| 457|Homo sapiens acetylcholine receptor
protein.
Length = 457
Score = 57.2 bits (132), Expect = 7e-08
Identities = 40/155 (25%), Positives = 74/155 (47%), Gaps = 8/155 (5%)
Frame = +2
Query: 191 KIVVNLTLHLRHASIRESESTVRMLAGLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRP 367
++ V L L ++ ++ E V L+ W+D L WN ++G + + SE++WRP
Sbjct: 50 EVTVGLQL-IQLINVDEVNQIVTTNVRLKQQWVDYNLKWNPDDYGGVKKIHIPSEKIWRP 108
Query: 368 DVVLLNAAATTAGDYAL----RARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFK 535
D+VL N A GD+A+ + + G ++W + + + ++P D Q C+ K
Sbjct: 109 DLVLYNNA---DGDFAIVKFTKVLLQYTGHITWTPPAIFKSYCEIIVTHFPFDEQNCSMK 165
Query: 536 FGSRMHNSDXMDF--VIDKRIYSMF-ESGAWDVTD 631
G+ ++ + D+ S F ESG W + +
Sbjct: 166 LGTWTYDGSVVAINPESDQPDLSNFMESGEWVIKE 200
>S77094-1|AAD14247.1| 457|Homo sapiens nicotinic acetylcholine
receptor alpha subunit|AChR protein.
Length = 457
Score = 57.2 bits (132), Expect = 7e-08
Identities = 40/155 (25%), Positives = 74/155 (47%), Gaps = 8/155 (5%)
Frame = +2
Query: 191 KIVVNLTLHLRHASIRESESTVRMLAGLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRP 367
++ V L L ++ ++ E V L+ W+D L WN ++G + + SE++WRP
Sbjct: 50 EVTVGLQL-IQLINVDEVNQIVTTNVRLKQQWVDYNLKWNPDDYGGVKKIHIPSEKIWRP 108
Query: 368 DVVLLNAAATTAGDYAL----RARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFK 535
D+VL N A GD+A+ + + G ++W + + + ++P D Q C+ K
Sbjct: 109 DLVLYNNA---DGDFAIVKFTKVLLQYTGHITWTPPAIFKSYCEIIVTHFPFDEQNCSMK 165
Query: 536 FGSRMHNSDXMDF--VIDKRIYSMF-ESGAWDVTD 631
G+ ++ + D+ S F ESG W + +
Sbjct: 166 LGTWTYDGSVVAINPESDQPDLSNFMESGEWVIKE 200
>BC006314-1|AAH06314.1| 269|Homo sapiens CHRNA1 protein protein.
Length = 269
Score = 57.2 bits (132), Expect = 7e-08
Identities = 40/155 (25%), Positives = 74/155 (47%), Gaps = 8/155 (5%)
Frame = +2
Query: 191 KIVVNLTLHLRHASIRESESTVRMLAGLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRP 367
++ V L L ++ ++ E V L+ W+D L WN ++G + + SE++WRP
Sbjct: 50 EVTVGLQL-IQLINVDEVNQIVTTNVRLKQQWVDYNLKWNPDDYGGVKKIHIPSEKIWRP 108
Query: 368 DVVLLNAAATTAGDYAL----RARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFK 535
D+VL N A GD+A+ + + G ++W + + + ++P D Q C+ K
Sbjct: 109 DLVLYNNA---DGDFAIVKFTKVLLQYTGHITWTPPAIFKSYCEIIVTHFPFDEQNCSMK 165
Query: 536 FGSRMHNSDXMDF--VIDKRIYSMF-ESGAWDVTD 631
G+ ++ + D+ S F ESG W + +
Sbjct: 166 LGTWTYDGSVVAINPESDQPDLSNFMESGEWVIKE 200
>AJ295237-1|CAC16144.1| 450|Homo sapiens neuronal nicotinic
acetylcholine receptor subunit4 protein.
Length = 450
Score = 57.2 bits (132), Expect = 7e-08
Identities = 45/165 (27%), Positives = 72/165 (43%), Gaps = 10/165 (6%)
Frame = +2
Query: 107 AEC---ENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHASIRESESTVRMLA- 268
AEC E +L L D L A Y P D+ +N+TL + + I + + ++L
Sbjct: 20 AECLGAEGRLALKLFRD-LFANYTSALRPVADTDQTLNVTLEVTLSQIIDMDERNQVLTL 78
Query: 269 --GLQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSN 436
++ W D L W+ +G + S +WRPD+VL N A A G + + +
Sbjct: 79 YLWIRQEWTDAYLRWDPNAYGGLDAIRIPSSLVWRPDIVLYNKADAQPPGSASTNVVLRH 138
Query: 437 NGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDXMD 571
+G+V W + + + +P D Q C FGS H +D
Sbjct: 139 DGAVRWDAPAITRSSCRVDVAAFPFDAQHCGLTFGSWTHGGHQLD 183
>AJ278118-1|CAC20435.1| 450|Homo sapiens neuronal nicotinic
acetylcholine alpha10 subunit protein.
Length = 450
Score = 57.2 bits (132), Expect = 7e-08
Identities = 45/165 (27%), Positives = 72/165 (43%), Gaps = 10/165 (6%)
Frame = +2
Query: 107 AEC---ENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHASIRESESTVRMLA- 268
AEC E +L L D L A Y P D+ +N+TL + + I + + ++L
Sbjct: 20 AECLGAEGRLALKLFRD-LFANYTSALRPVADTDQTLNVTLEVTLSQIIDMDERNQVLTL 78
Query: 269 --GLQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSN 436
++ W D L W+ +G + S +WRPD+VL N A A G + + +
Sbjct: 79 YLWIRQEWTDAYLRWDPNAYGGLDAIRIPSSLVWRPDIVLYNKADAQPPGSASTNVVLRH 138
Query: 437 NGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDXMD 571
+G+V W + + + +P D Q C FGS H +D
Sbjct: 139 DGAVRWDAPAITRSSCRVDVAAFPFDAQHCGLTFGSWTHGGHQLD 183
>AF327367-1|AAK14333.1| 450|Homo sapiens nicotinic acetylcholine
receptor subunit alpha 10 protein.
Length = 450
Score = 57.2 bits (132), Expect = 7e-08
Identities = 45/165 (27%), Positives = 72/165 (43%), Gaps = 10/165 (6%)
Frame = +2
Query: 107 AEC---ENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHASIRESESTVRMLA- 268
AEC E +L L D L A Y P D+ +N+TL + + I + + ++L
Sbjct: 20 AECLGAEGRLALKLFRD-LFANYTSALRPVADTDQTLNVTLEVTLSQIIDMDERNQVLTL 78
Query: 269 --GLQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSN 436
++ W D L W+ +G + S +WRPD+VL N A A G + + +
Sbjct: 79 YLWIRQEWTDAYLRWDPNAYGGLDAIRIPSSLVWRPDIVLYNKADAQPPGSASTNVVLRH 138
Query: 437 NGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDXMD 571
+G+V W + + + +P D Q C FGS H +D
Sbjct: 139 DGAVRWDAPAITRSSCRVDVAAFPFDAQHCGLTFGSWTHGGHQLD 183
>AF199235-1|AAG00795.2| 450|Homo sapiens nicotinic acetylcholine
receptor subunit alpha 10 protein.
Length = 450
Score = 57.2 bits (132), Expect = 7e-08
Identities = 45/165 (27%), Positives = 72/165 (43%), Gaps = 10/165 (6%)
Frame = +2
Query: 107 AEC---ENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHASIRESESTVRMLA- 268
AEC E +L L D L A Y P D+ +N+TL + + I + + ++L
Sbjct: 20 AECLGAEGRLALKLFRD-LFANYTSALRPVADTDQTLNVTLEVTLSQIIDMDERNQVLTL 78
Query: 269 --GLQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSN 436
++ W D L W+ +G + S +WRPD+VL N A A G + + +
Sbjct: 79 YLWIRQEWTDAYLRWDPNAYGGLDAIRIPSSLVWRPDIVLYNKADAQPPGSASTNVVLRH 138
Query: 437 NGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDXMD 571
+G+V W + + + +P D Q C FGS H +D
Sbjct: 139 DGAVRWDAPAITRSSCRVDVAAFPFDAQHCGLTFGSWTHGGHQLD 183
>AC018890-1|AAY14687.1| 457|Homo sapiens unknown protein.
Length = 457
Score = 57.2 bits (132), Expect = 7e-08
Identities = 40/155 (25%), Positives = 74/155 (47%), Gaps = 8/155 (5%)
Frame = +2
Query: 191 KIVVNLTLHLRHASIRESESTVRMLAGLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRP 367
++ V L L ++ ++ E V L+ W+D L WN ++G + + SE++WRP
Sbjct: 50 EVTVGLQL-IQLINVDEVNQIVTTNVRLKQQWVDYNLKWNPDDYGGVKKIHIPSEKIWRP 108
Query: 368 DVVLLNAAATTAGDYAL----RARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFK 535
D+VL N A GD+A+ + + G ++W + + + ++P D Q C+ K
Sbjct: 109 DLVLYNNA---DGDFAIVKFTKVLLQYTGHITWTPPAIFKSYCEIIVTHFPFDEQNCSMK 165
Query: 536 FGSRMHNSDXMDF--VIDKRIYSMF-ESGAWDVTD 631
G+ ++ + D+ S F ESG W + +
Sbjct: 166 LGTWTYDGSVVAINPESDQPDLSNFMESGEWVIKE 200
>X55019-1|CAA38759.1| 517|Homo sapiens acetylcholine receptor delta
subunit protein.
Length = 517
Score = 56.4 bits (130), Expect = 1e-07
Identities = 38/134 (28%), Positives = 63/134 (47%), Gaps = 7/134 (5%)
Frame = +2
Query: 164 YDRESPP----DSKIVVNLTLHLRHA-SIRESESTVRMLAGLQMNWIDKRLSWNAGEWG- 325
Y++E P + + V L L L + S++E E T+ ++ W D RL WNA E+G
Sbjct: 38 YNKELRPVAHKEESVDVALALTLSNLISLKEVEETLTTNVWIEHGWTDNRLKWNAEEFGN 97
Query: 326 CSTWLVSSERLWRPDVVL-LNAAATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDN 502
S + + +W P++VL N + Y+ V + G V W+ + + +
Sbjct: 98 ISVLRLPPDMVWLPEIVLENNNDGSFQISYSCNVLVYHYGFVYWLPPAIFRSSCPISVTY 157
Query: 503 WPNDMQTCTFKFGS 544
+P D Q C+ KF S
Sbjct: 158 FPFDWQNCSLKFSS 171
>BC093925-1|AAH93925.1| 517|Homo sapiens cholinergic receptor,
nicotinic, delta protein.
Length = 517
Score = 56.4 bits (130), Expect = 1e-07
Identities = 38/134 (28%), Positives = 63/134 (47%), Gaps = 7/134 (5%)
Frame = +2
Query: 164 YDRESPP----DSKIVVNLTLHLRHA-SIRESESTVRMLAGLQMNWIDKRLSWNAGEWG- 325
Y++E P + + V L L L + S++E E T+ ++ W D RL WNA E+G
Sbjct: 38 YNKELRPVAHKEESVDVALALTLSNLISLKEVEETLTTNVWIEHGWTDNRLKWNAEEFGN 97
Query: 326 CSTWLVSSERLWRPDVVL-LNAAATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDN 502
S + + +W P++VL N + Y+ V + G V W+ + + +
Sbjct: 98 ISVLRLPPDMVWLPEIVLENNNDGSFQISYSCNVLVYHYGFVYWLPPAIFRSSCPISVTY 157
Query: 503 WPNDMQTCTFKFGS 544
+P D Q C+ KF S
Sbjct: 158 FPFDWQNCSLKFSS 171
>BC093923-1|AAH93923.1| 517|Homo sapiens cholinergic receptor,
nicotinic, delta protein.
Length = 517
Score = 56.4 bits (130), Expect = 1e-07
Identities = 38/134 (28%), Positives = 63/134 (47%), Gaps = 7/134 (5%)
Frame = +2
Query: 164 YDRESPP----DSKIVVNLTLHLRHA-SIRESESTVRMLAGLQMNWIDKRLSWNAGEWG- 325
Y++E P + + V L L L + S++E E T+ ++ W D RL WNA E+G
Sbjct: 38 YNKELRPVAHKEESVDVALALTLSNLISLKEVEETLTTNVWIEHGWTDNRLKWNAEEFGN 97
Query: 326 CSTWLVSSERLWRPDVVL-LNAAATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDN 502
S + + +W P++VL N + Y+ V + G V W+ + + +
Sbjct: 98 ISVLRLPPDMVWLPEIVLENNNDGSFQISYSCNVLVYHYGFVYWLPPAIFRSSCPISVTY 157
Query: 503 WPNDMQTCTFKFGS 544
+P D Q C+ KF S
Sbjct: 158 FPFDWQNCSLKFSS 171
>AC092165-2|AAY24102.1| 517|Homo sapiens unknown protein.
Length = 517
Score = 56.4 bits (130), Expect = 1e-07
Identities = 38/134 (28%), Positives = 63/134 (47%), Gaps = 7/134 (5%)
Frame = +2
Query: 164 YDRESPP----DSKIVVNLTLHLRHA-SIRESESTVRMLAGLQMNWIDKRLSWNAGEWG- 325
Y++E P + + V L L L + S++E E T+ ++ W D RL WNA E+G
Sbjct: 38 YNKELRPVAHKEESVDVALALTLSNLISLKEVEETLTTNVWIEHGWTDNRLKWNAEEFGN 97
Query: 326 CSTWLVSSERLWRPDVVL-LNAAATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDN 502
S + + +W P++VL N + Y+ V + G V W+ + + +
Sbjct: 98 ISVLRLPPDMVWLPEIVLENNNDGSFQISYSCNVLVYHYGFVYWLPPAIFRSSCPISVTY 157
Query: 503 WPNDMQTCTFKFGS 544
+P D Q C+ KF S
Sbjct: 158 FPFDWQNCSLKFSS 171
>Z23141-1|CAA80672.1| 479|Homo sapiens cholinergic receptor,
nicotinic, alpha polypeptide 7 protein.
Length = 479
Score = 56.0 bits (129), Expect = 2e-07
Identities = 32/124 (25%), Positives = 58/124 (46%), Gaps = 3/124 (2%)
Frame = +2
Query: 272 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSNNGS 445
LQM+W D L WN E+ G T ++W+PD++L N+A + V+++G
Sbjct: 55 LQMSWTDHYLQWNVSEYPGVKTVRFPDGQIWKPDILLYNSADERFDATFHTNVLVNSSGH 114
Query: 446 VSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDXMDFVIDKR-IYSMFESGAWD 622
++ + + + +P D+Q C KFGS + +D + + I +G WD
Sbjct: 115 CQYLPPGIFKSSCYIDVRWFPFDVQHCKLKFGSWSYGGWSLDLQMQEADISGYIPNGEWD 174
Query: 623 VTDL 634
+ +
Sbjct: 175 LVGI 178
>Y08420-1|CAA69697.1| 502|Homo sapiens nicotinic acetylcholine
receptor alpha7 subunit precursor protein.
Length = 502
Score = 56.0 bits (129), Expect = 2e-07
Identities = 32/124 (25%), Positives = 58/124 (46%), Gaps = 3/124 (2%)
Frame = +2
Query: 272 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSNNGS 445
LQM+W D L WN E+ G T ++W+PD++L N+A + V+++G
Sbjct: 78 LQMSWTDHYLQWNVSEYPGVKTVRFPDGQIWKPDILLYNSADERFDATFHTNVLVNSSGH 137
Query: 446 VSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDXMDFVIDKR-IYSMFESGAWD 622
++ + + + +P D+Q C KFGS + +D + + I +G WD
Sbjct: 138 CQYLPPGIFKSSCYIDVRWFPFDVQHCKLKFGSWSYGGWSLDLQMQEADISGYIPNGEWD 197
Query: 623 VTDL 634
+ +
Sbjct: 198 LVGI 201
>X70297-1|CAA49778.1| 502|Homo sapiens neuronal nicotinic
acetylocholine receptor alpha-7 subunit protein.
Length = 502
Score = 56.0 bits (129), Expect = 2e-07
Identities = 32/124 (25%), Positives = 58/124 (46%), Gaps = 3/124 (2%)
Frame = +2
Query: 272 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSNNGS 445
LQM+W D L WN E+ G T ++W+PD++L N+A + V+++G
Sbjct: 78 LQMSWTDHYLQWNVSEYPGVKTVRFPDGQIWKPDILLYNSADERFDATFHTNVLVNSSGH 137
Query: 446 VSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDXMDFVIDKR-IYSMFESGAWD 622
++ + + + +P D+Q C KFGS + +D + + I +G WD
Sbjct: 138 CQYLPPGIFKSSCYIDVRWFPFDVQHCKLKFGSWSYGGWSLDLQMQEADISGYIPNGEWD 197
Query: 623 VTDL 634
+ +
Sbjct: 198 LVGI 201
>U62436-1|AAB40114.1| 502|Homo sapiens nicotinic acetylcholine
receptor alpha7 subunit precursor protein.
Length = 502
Score = 56.0 bits (129), Expect = 2e-07
Identities = 32/124 (25%), Positives = 58/124 (46%), Gaps = 3/124 (2%)
Frame = +2
Query: 272 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSNNGS 445
LQM+W D L WN E+ G T ++W+PD++L N+A + V+++G
Sbjct: 78 LQMSWTDHYLQWNVSEYPGVKTVRFPDGQIWKPDILLYNSADERFDATFHTNVLVNSSGH 137
Query: 446 VSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDXMDFVIDKR-IYSMFESGAWD 622
++ + + + +P D+Q C KFGS + +D + + I +G WD
Sbjct: 138 CQYLPPGIFKSSCYIDVRWFPFDVQHCKLKFGSWSYGGWSLDLQMQEADISGYIPNGEWD 197
Query: 623 VTDL 634
+ +
Sbjct: 198 LVGI 201
>AJ586911-1|CAE52911.1| 502|Homo sapiens nicotinic acetylcholine
alpha-7 subunit protein.
Length = 502
Score = 56.0 bits (129), Expect = 2e-07
Identities = 32/124 (25%), Positives = 58/124 (46%), Gaps = 3/124 (2%)
Frame = +2
Query: 272 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSNNGS 445
LQM+W D L WN E+ G T ++W+PD++L N+A + V+++G
Sbjct: 78 LQMSWTDHYLQWNVSEYPGVKTVRFPDGQIWKPDILLYNSADERFDATFHTNVLVNSSGH 137
Query: 446 VSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDXMDFVIDKR-IYSMFESGAWD 622
++ + + + +P D+Q C KFGS + +D + + I +G WD
Sbjct: 138 CQYLPPGIFKSSCYIDVRWFPFDVQHCKLKFGSWSYGGWSLDLQMQEADISGYIPNGEWD 197
Query: 623 VTDL 634
+ +
Sbjct: 198 LVGI 201
>U40583-1|AAA83561.1| 502|Homo sapiens alpha 7 neuronal nicotinic
acetylcholine receptor protein.
Length = 502
Score = 54.8 bits (126), Expect = 4e-07
Identities = 32/124 (25%), Positives = 57/124 (45%), Gaps = 3/124 (2%)
Frame = +2
Query: 272 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSNNGS 445
LQM+W D L WN E+ G T ++W+PD++L N+A + V+ +G
Sbjct: 78 LQMSWTDHYLQWNVSEYPGVKTVRFPDGQIWKPDILLYNSADERFDATFHTNVLVNPSGH 137
Query: 446 VSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDXMDFVIDKR-IYSMFESGAWD 622
++ + + + +P D+Q C KFGS + +D + + I +G WD
Sbjct: 138 CQYLPPGIFKSSCYIDVRWFPFDVQHCKLKFGSWSYGGWSLDLQMQEADISGYIPNGEWD 197
Query: 623 VTDL 634
+ +
Sbjct: 198 LVGI 201
>AF385585-1|AAK68111.1| 502|Homo sapiens nicotinic cholinergic
receptor alpha 7 protein.
Length = 502
Score = 54.8 bits (126), Expect = 4e-07
Identities = 32/124 (25%), Positives = 57/124 (45%), Gaps = 3/124 (2%)
Frame = +2
Query: 272 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSNNGS 445
LQM+W D L WN E+ G T ++W+PD++L N+A + V+ +G
Sbjct: 78 LQMSWTDHYLQWNVSEYPGVKTVRFPDGQIWKPDILLYNSADERFDATFHTNVLVNPSGH 137
Query: 446 VSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDXMDFVIDKR-IYSMFESGAWD 622
++ + + + +P D+Q C KFGS + +D + + I +G WD
Sbjct: 138 CQYLPPGIFKSSCYIDVRWFPFDVQHCKLKFGSWSYGGWSLDLQMQEADISGYIPNGEWD 197
Query: 623 VTDL 634
+ +
Sbjct: 198 LVGI 201
>M59216-1|AAA35862.1| 474|Homo sapiens gamma-aminobutyric acid
receptor beta-1 subunit protein.
Length = 474
Score = 52.4 bits (120), Expect = 2e-06
Identities = 43/169 (25%), Positives = 73/169 (43%), Gaps = 7/169 (4%)
Frame = +2
Query: 89 CAIASAAECENATSLSLMIDSLLATYDRESPPD-SKIVVNLTLHLRHASI---RESESTV 256
C S E N + + +D LL YD PD V++ + + ASI E
Sbjct: 23 CCAHSTNEPSNMSYVKETVDRLLKGYDIRLRPDFGGPPVDVGMRIDVASIDMVSEVNMDY 82
Query: 257 RMLAGLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---AR 427
+ Q +W DKRLS++ + +++LW PD LN + ++ R
Sbjct: 83 TLTMYFQQSWKDKRLSYSGIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIR 142
Query: 428 VSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDXMDF 574
+ +G+V + R+ + M L +P D Q CT + S + +D ++F
Sbjct: 143 LHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEF 191
>BC110597-1|AAI10598.1| 411|Homo sapiens ligand-gated ion channel,
zinc activated 1 protein.
Length = 411
Score = 52.4 bits (120), Expect = 2e-06
Identities = 28/108 (25%), Positives = 51/108 (47%)
Frame = +2
Query: 251 TVRMLAGLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARV 430
T+ + L+++W+D RL+WN + E LW P + +L A D + +ARV
Sbjct: 79 TMSSMLLLRLSWLDTRLAWNTSAHPRHAITLPWESLWTPRLTILEALWVDWRDQSPQARV 138
Query: 431 SNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDXMDF 574
+G V L T + +L ++P D C+ F + + + ++F
Sbjct: 139 DQDGHVKLNLALTTETNCNFELLHFPRDHSNCSLSFYALSNTAMELEF 186
>AF512521-1|AAO20969.1| 411|Homo sapiens ligand-gated ion channel
subunit protein.
Length = 411
Score = 52.4 bits (120), Expect = 2e-06
Identities = 28/108 (25%), Positives = 51/108 (47%)
Frame = +2
Query: 251 TVRMLAGLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARV 430
T+ + L+++W+D RL+WN + E LW P + +L A D + +ARV
Sbjct: 79 TMSSMLLLRLSWLDTRLAWNTSAHPRHAITLPWESLWTPRLTILEALWVDWRDQSPQARV 138
Query: 431 SNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDXMDF 574
+G V L T + +L ++P D C+ F + + + ++F
Sbjct: 139 DQDGHVKLNLALTTETNCNFELLHFPRDHSNCSLSFYALSNTAMELEF 186
>AB223030-1|BAE19924.1| 411|Homo sapiens ligand-gated ion-channel
receptor L2 protein.
Length = 411
Score = 52.0 bits (119), Expect = 3e-06
Identities = 28/108 (25%), Positives = 51/108 (47%)
Frame = +2
Query: 251 TVRMLAGLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARV 430
T+ + L+++W+D RL+WN + E LW P + +L A D + +ARV
Sbjct: 79 TMSSMLLLRLSWLDTRLAWNTSAHPRHAITLPWESLWTPRLTILEALWVDWRDQSPQARV 138
Query: 431 SNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDXMDF 574
+G V L T + +L ++P D C+ F + + + ++F
Sbjct: 139 DQDGHVKLNLALATETNCNFELLHFPRDHSNCSLSFYALSNTAMELEF 186
>X14767-1|CAA32875.1| 474|Homo sapiens GABA-A receptor beta 1
subunit protein.
Length = 474
Score = 51.6 bits (118), Expect = 4e-06
Identities = 43/169 (25%), Positives = 72/169 (42%), Gaps = 7/169 (4%)
Frame = +2
Query: 89 CAIASAAECENATSLSLMIDSLLATYDRESPPD-SKIVVNLTLHLRHASI---RESESTV 256
C S E N + +D LL YD PD V++ + + ASI E
Sbjct: 23 CCAHSTNEPSNMPYVKETVDRLLKGYDIRLRPDFGGPPVDVGMRIDVASIDMVSEVNMDY 82
Query: 257 RMLAGLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---AR 427
+ Q +W DKRLS++ + +++LW PD LN + ++ R
Sbjct: 83 TLTMYFQQSWKDKRLSYSGIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIR 142
Query: 428 VSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDXMDF 574
+ +G+V + R+ + M L +P D Q CT + S + +D ++F
Sbjct: 143 LHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEF 191
>BC111802-1|AAI11803.1| 465|Homo sapiens CHRNG protein protein.
Length = 465
Score = 51.6 bits (118), Expect = 4e-06
Identities = 35/113 (30%), Positives = 57/113 (50%), Gaps = 7/113 (6%)
Frame = +2
Query: 140 MIDSLLATYD---RESPPDSKIV-VNLTLHLRHA-SIRESESTVRMLAGLQMNWIDKRLS 304
++ L+ YD R + DS +V V+L L L + S+ E E + ++M W D RL
Sbjct: 29 LLADLMQNYDPNLRPAERDSDVVNVSLKLTLTNLISLNEREEALTTNVWIEMQWCDYRLR 88
Query: 305 WNAGEW-GCSTWLVSSERLWRPDVVLLNAAAT-TAGDYALRARVSNNGSVSWI 457
W+ ++ G V S +WRPD+VL N + T + + L+ + S+ WI
Sbjct: 89 WDPRDYEGLWVLRVPSTMVWRPDIVLENKSQTYSTNEIDLQLSQEDGQSIEWI 141
>AK122638-1|BAC85499.1| 266|Homo sapiens yte protein of 76kDa)
(LCP2). protein.
Length = 266
Score = 51.2 bits (117), Expect = 5e-06
Identities = 27/96 (28%), Positives = 45/96 (46%)
Frame = +2
Query: 251 TVRMLAGLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARV 430
T+ + L+++W+D RL+WN + E LW P + +L A D + +ARV
Sbjct: 80 TMSSMLLLRLSWLDTRLAWNTSAHPRHAITLPWESLWTPRLTILEALWVDWRDQSPQARV 139
Query: 431 SNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKF 538
+G V L T + +L ++P D C+ F
Sbjct: 140 DQDGHVKLNLALTTETNCNFELLHFPRDHSNCSLSF 175
>S77554-1|AAB33983.1| 474|Homo sapiens GABAA receptor beta 2
subunit protein.
Length = 474
Score = 50.8 bits (116), Expect = 6e-06
Identities = 41/169 (24%), Positives = 71/169 (42%), Gaps = 7/169 (4%)
Frame = +2
Query: 89 CAIASAAECENATSLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAS-IRESESTV 256
CA S + N + + +D LL YD PD + V + + + + E
Sbjct: 23 CA-QSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDIASIDMVSEVNMDY 81
Query: 257 RMLAGLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---AR 427
+ Q W DKRLS+N + +++LW PD LN + ++ R
Sbjct: 82 TLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIR 141
Query: 428 VSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDXMDF 574
+ +G+V + R+ + M L +P D Q CT + S + +D ++F
Sbjct: 142 LHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEF 190
>S77553-1|AAB33982.1| 512|Homo sapiens GABAA receptor beta 2
subunit protein.
Length = 512
Score = 50.8 bits (116), Expect = 6e-06
Identities = 41/169 (24%), Positives = 71/169 (42%), Gaps = 7/169 (4%)
Frame = +2
Query: 89 CAIASAAECENATSLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAS-IRESESTV 256
CA S + N + + +D LL YD PD + V + + + + E
Sbjct: 23 CA-QSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDIASIDMVSEVNMDY 81
Query: 257 RMLAGLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---AR 427
+ Q W DKRLS+N + +++LW PD LN + ++ R
Sbjct: 82 TLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIR 141
Query: 428 VSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDXMDF 574
+ +G+V + R+ + M L +P D Q CT + S + +D ++F
Sbjct: 142 LHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEF 190
>S67368-1|AAB29370.1| 474|Homo sapiens gamma-aminobutyric acid A
receptor beta 2 subunit protein.
Length = 474
Score = 50.8 bits (116), Expect = 6e-06
Identities = 41/169 (24%), Positives = 71/169 (42%), Gaps = 7/169 (4%)
Frame = +2
Query: 89 CAIASAAECENATSLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAS-IRESESTV 256
CA S + N + + +D LL YD PD + V + + + + E
Sbjct: 23 CA-QSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDIASIDMVSEVNMDY 81
Query: 257 RMLAGLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---AR 427
+ Q W DKRLS+N + +++LW PD LN + ++ R
Sbjct: 82 TLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIR 141
Query: 428 VSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDXMDF 574
+ +G+V + R+ + M L +P D Q CT + S + +D ++F
Sbjct: 142 LHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEF 190
>L08485-1|AAA58490.1| 462|Homo sapiens GABA-benzodiazepine receptor
alpha-5-subunit protein.
Length = 462
Score = 50.8 bits (116), Expect = 6e-06
Identities = 37/161 (22%), Positives = 72/161 (44%), Gaps = 7/161 (4%)
Frame = +2
Query: 116 ENATSLSLMIDSLLATYDRESPPD--SKIV-VNLTLHLRH-ASIRESESTVRMLAGLQMN 283
+N T + ++D LL YD P +I V +++ + ++E + + +
Sbjct: 44 DNITIFTRILDGLLDGYDNRLRPGLGERITQVRTDIYVTSFGPVSDTEMEYTIDVFFRQS 103
Query: 284 WIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSW 454
W D+RL + + + ++W PD N + A + R+ ++G++ +
Sbjct: 104 WKDERLRFKGPMQRLPLNNLLASKIWTPDTFFHNGKKSIAHNMTTPNKLLRLEDDGTLLY 163
Query: 455 IKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDXMDFV 577
RL IS MQL+++P D C KFGS + + + +V
Sbjct: 164 TMRLTISAECPMQLEDFPMDAHACPLKFGSYAYPNSEVVYV 204
>BT009830-1|AAP88832.1| 462|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 5 protein.
Length = 462
Score = 50.8 bits (116), Expect = 6e-06
Identities = 37/161 (22%), Positives = 72/161 (44%), Gaps = 7/161 (4%)
Frame = +2
Query: 116 ENATSLSLMIDSLLATYDRESPPD--SKIV-VNLTLHLRH-ASIRESESTVRMLAGLQMN 283
+N T + ++D LL YD P +I V +++ + ++E + + +
Sbjct: 44 DNITIFTRILDGLLDGYDNRLRPGLGERITQVRTDIYVTSFGPVSDTEMEYTIDVFFRQS 103
Query: 284 WIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSW 454
W D+RL + + + ++W PD N + A + R+ ++G++ +
Sbjct: 104 WKDERLRFKGPMQRLPLNNLLASKIWTPDTFFHNGKKSIAHNMTTPNKLLRLEDDGTLLY 163
Query: 455 IKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDXMDFV 577
RL IS MQL+++P D C KFGS + + + +V
Sbjct: 164 TMRLTISAECPMQLEDFPMDAHACPLKFGSYAYPNSEVVYV 204
>BC113422-1|AAI13423.1| 462|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 5 protein.
Length = 462
Score = 50.8 bits (116), Expect = 6e-06
Identities = 37/161 (22%), Positives = 72/161 (44%), Gaps = 7/161 (4%)
Frame = +2
Query: 116 ENATSLSLMIDSLLATYDRESPPD--SKIV-VNLTLHLRH-ASIRESESTVRMLAGLQMN 283
+N T + ++D LL YD P +I V +++ + ++E + + +
Sbjct: 44 DNITIFTRILDGLLDGYDNRLRPGLGERITQVRTDIYVTSFGPVSDTEMEYTIDVFFRQS 103
Query: 284 WIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSW 454
W D+RL + + + ++W PD N + A + R+ ++G++ +
Sbjct: 104 WKDERLRFKGPMQRLPLNNLLASKIWTPDTFFHNGKKSIAHNMTTPNKLLRLEDDGTLLY 163
Query: 455 IKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDXMDFV 577
RL IS MQL+++P D C KFGS + + + +V
Sbjct: 164 TMRLTISAECPMQLEDFPMDAHACPLKFGSYAYPNSEVVYV 204
>BC111979-1|AAI11980.1| 462|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 5, precursor protein.
Length = 462
Score = 50.8 bits (116), Expect = 6e-06
Identities = 37/161 (22%), Positives = 72/161 (44%), Gaps = 7/161 (4%)
Frame = +2
Query: 116 ENATSLSLMIDSLLATYDRESPPD--SKIV-VNLTLHLRH-ASIRESESTVRMLAGLQMN 283
+N T + ++D LL YD P +I V +++ + ++E + + +
Sbjct: 44 DNITIFTRILDGLLDGYDNRLRPGLGERITQVRTDIYVTSFGPVSDTEMEYTIDVFFRQS 103
Query: 284 WIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSW 454
W D+RL + + + ++W PD N + A + R+ ++G++ +
Sbjct: 104 WKDERLRFKGPMQRLPLNNLLASKIWTPDTFFHNGKKSIAHNMTTPNKLLRLEDDGTLLY 163
Query: 455 IKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDXMDFV 577
RL IS MQL+++P D C KFGS + + + +V
Sbjct: 164 TMRLTISAECPMQLEDFPMDAHACPLKFGSYAYPNSEVVYV 204
>BC105639-1|AAI05640.1| 474|Homo sapiens GABRB2 protein protein.
Length = 474
Score = 50.8 bits (116), Expect = 6e-06
Identities = 41/169 (24%), Positives = 71/169 (42%), Gaps = 7/169 (4%)
Frame = +2
Query: 89 CAIASAAECENATSLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAS-IRESESTV 256
CA S + N + + +D LL YD PD + V + + + + E
Sbjct: 23 CA-QSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDIASIDMVSEVNMDY 81
Query: 257 RMLAGLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---AR 427
+ Q W DKRLS+N + +++LW PD LN + ++ R
Sbjct: 82 TLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIR 141
Query: 428 VSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDXMDF 574
+ +G+V + R+ + M L +P D Q CT + S + +D ++F
Sbjct: 142 LHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEF 190
>BC099719-1|AAH99719.1| 474|Homo sapiens GABRB2 protein protein.
Length = 474
Score = 50.8 bits (116), Expect = 6e-06
Identities = 41/169 (24%), Positives = 71/169 (42%), Gaps = 7/169 (4%)
Frame = +2
Query: 89 CAIASAAECENATSLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAS-IRESESTV 256
CA S + N + + +D LL YD PD + V + + + + E
Sbjct: 23 CA-QSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDIASIDMVSEVNMDY 81
Query: 257 RMLAGLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---AR 427
+ Q W DKRLS+N + +++LW PD LN + ++ R
Sbjct: 82 TLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIR 141
Query: 428 VSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDXMDF 574
+ +G+V + R+ + M L +P D Q CT + S + +D ++F
Sbjct: 142 LHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEF 190
>BC099705-1|AAH99705.1| 474|Homo sapiens GABRB2 protein protein.
Length = 474
Score = 50.8 bits (116), Expect = 6e-06
Identities = 41/169 (24%), Positives = 71/169 (42%), Gaps = 7/169 (4%)
Frame = +2
Query: 89 CAIASAAECENATSLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAS-IRESESTV 256
CA S + N + + +D LL YD PD + V + + + + E
Sbjct: 23 CA-QSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDIASIDMVSEVNMDY 81
Query: 257 RMLAGLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---AR 427
+ Q W DKRLS+N + +++LW PD LN + ++ R
Sbjct: 82 TLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIR 141
Query: 428 VSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDXMDF 574
+ +G+V + R+ + M L +P D Q CT + S + +D ++F
Sbjct: 142 LHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEF 190
>S81944-1|AAB36480.1| 453|Homo sapiens gamma-aminobutyric acid type
A receptor alpha 6 subunit protein.
Length = 453
Score = 49.6 bits (113), Expect = 1e-05
Identities = 38/146 (26%), Positives = 62/146 (42%), Gaps = 7/146 (4%)
Frame = +2
Query: 128 SLSLMIDSLLATYD-RESPPDSKIVVNLTLHLRHAS---IRESESTVRMLAGLQMNWIDK 295
++S ++D+LL YD R P V + + S + + E M + W D+
Sbjct: 31 NVSRILDNLLEGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTDE 90
Query: 296 RLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRA---RVSNNGSVSWIKRL 466
RL + S + ++W PD N + A + R+ NG++ + RL
Sbjct: 91 RLKFGGPTEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTMRL 150
Query: 467 DISTPISMQLDNWPNDMQTCTFKFGS 544
I+ M+L N+P D C KFGS
Sbjct: 151 TINADCPMRLVNFPMDGHACPLKFGS 176
>BC099641-1|AAH99641.1| 453|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 6 protein.
Length = 453
Score = 49.6 bits (113), Expect = 1e-05
Identities = 38/146 (26%), Positives = 62/146 (42%), Gaps = 7/146 (4%)
Frame = +2
Query: 128 SLSLMIDSLLATYD-RESPPDSKIVVNLTLHLRHAS---IRESESTVRMLAGLQMNWIDK 295
++S ++D+LL YD R P V + + S + + E M + W D+
Sbjct: 31 NVSRILDNLLEGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTDE 90
Query: 296 RLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRA---RVSNNGSVSWIKRL 466
RL + S + ++W PD N + A + R+ NG++ + RL
Sbjct: 91 RLKFGGPTEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTMRL 150
Query: 467 DISTPISMQLDNWPNDMQTCTFKFGS 544
I+ M+L N+P D C KFGS
Sbjct: 151 TINADCPMRLVNFPMDGHACPLKFGS 176
>BC099640-1|AAH99640.1| 453|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 6 protein.
Length = 453
Score = 49.6 bits (113), Expect = 1e-05
Identities = 38/146 (26%), Positives = 62/146 (42%), Gaps = 7/146 (4%)
Frame = +2
Query: 128 SLSLMIDSLLATYD-RESPPDSKIVVNLTLHLRHAS---IRESESTVRMLAGLQMNWIDK 295
++S ++D+LL YD R P V + + S + + E M + W D+
Sbjct: 31 NVSRILDNLLEGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTDE 90
Query: 296 RLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRA---RVSNNGSVSWIKRL 466
RL + S + ++W PD N + A + R+ NG++ + RL
Sbjct: 91 RLKFGGPTEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTMRL 150
Query: 467 DISTPISMQLDNWPNDMQTCTFKFGS 544
I+ M+L N+P D C KFGS
Sbjct: 151 TINADCPMRLVNFPMDGHACPLKFGS 176
>BC096242-1|AAH96242.1| 453|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 6 protein.
Length = 453
Score = 49.6 bits (113), Expect = 1e-05
Identities = 38/146 (26%), Positives = 62/146 (42%), Gaps = 7/146 (4%)
Frame = +2
Query: 128 SLSLMIDSLLATYD-RESPPDSKIVVNLTLHLRHAS---IRESESTVRMLAGLQMNWIDK 295
++S ++D+LL YD R P V + + S + + E M + W D+
Sbjct: 31 NVSRILDNLLEGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTDE 90
Query: 296 RLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRA---RVSNNGSVSWIKRL 466
RL + S + ++W PD N + A + R+ NG++ + RL
Sbjct: 91 RLKFGGPTEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTMRL 150
Query: 467 DISTPISMQLDNWPNDMQTCTFKFGS 544
I+ M+L N+P D C KFGS
Sbjct: 151 TINADCPMRLVNFPMDGHACPLKFGS 176
>BC096241-1|AAH96241.1| 453|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 6 protein.
Length = 453
Score = 49.6 bits (113), Expect = 1e-05
Identities = 38/146 (26%), Positives = 62/146 (42%), Gaps = 7/146 (4%)
Frame = +2
Query: 128 SLSLMIDSLLATYD-RESPPDSKIVVNLTLHLRHAS---IRESESTVRMLAGLQMNWIDK 295
++S ++D+LL YD R P V + + S + + E M + W D+
Sbjct: 31 NVSRILDNLLEGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTDE 90
Query: 296 RLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRA---RVSNNGSVSWIKRL 466
RL + S + ++W PD N + A + R+ NG++ + RL
Sbjct: 91 RLKFGGPTEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTMRL 150
Query: 467 DISTPISMQLDNWPNDMQTCTFKFGS 544
I+ M+L N+P D C KFGS
Sbjct: 151 TINADCPMRLVNFPMDGHACPLKFGS 176
>U77731-2|AAB38273.1| 360|Homo sapiens glycine receptor alpha 2B
subunit protein.
Length = 360
Score = 49.2 bits (112), Expect = 2e-05
Identities = 39/135 (28%), Positives = 60/135 (44%), Gaps = 8/135 (5%)
Frame = +2
Query: 164 YDRESPPDSK-IVVNLTLHL---RHASIRESESTVRMLAGLQMNWIDKRLSWNAGEWGCS 331
YD P+ K VN+T ++ SI E+ R+ L+ W D RL+++
Sbjct: 58 YDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDSRLAYSEYPDDSL 117
Query: 332 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLD 499
S + +W+PD+ N D R+S NG V + RL ++ M L
Sbjct: 118 DLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLK 177
Query: 500 NWPNDMQTCTFKFGS 544
N+P D+QTCT + S
Sbjct: 178 NFPMDVQTCTMQLES 192
>CR450343-1|CAG29339.1| 452|Homo sapiens GLRA2 protein.
Length = 452
Score = 49.2 bits (112), Expect = 2e-05
Identities = 39/135 (28%), Positives = 60/135 (44%), Gaps = 8/135 (5%)
Frame = +2
Query: 164 YDRESPPDSK-IVVNLTLHL---RHASIRESESTVRMLAGLQMNWIDKRLSWNAGEWGCS 331
YD P+ K VN+T ++ SI E+ R+ L+ W D RL+++
Sbjct: 58 YDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDSRLAYSEYPDDSL 117
Query: 332 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLD 499
S + +W+PD+ N D R+S NG V + RL ++ M L
Sbjct: 118 DLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLK 177
Query: 500 NWPNDMQTCTFKFGS 544
N+P D+QTCT + S
Sbjct: 178 NFPMDVQTCTMQLES 192
>AY437084-1|AAR87843.1| 452|Homo sapiens glycine receptor alpha2
subunit B protein.
Length = 452
Score = 49.2 bits (112), Expect = 2e-05
Identities = 39/135 (28%), Positives = 60/135 (44%), Gaps = 8/135 (5%)
Frame = +2
Query: 164 YDRESPPDSK-IVVNLTLHL---RHASIRESESTVRMLAGLQMNWIDKRLSWNAGEWGCS 331
YD P+ K VN+T ++ SI E+ R+ L+ W D RL+++
Sbjct: 58 YDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDSRLAYSEYPDDSL 117
Query: 332 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLD 499
S + +W+PD+ N D R+S NG V + RL ++ M L
Sbjct: 118 DLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLK 177
Query: 500 NWPNDMQTCTFKFGS 544
N+P D+QTCT + S
Sbjct: 178 NFPMDVQTCTMQLES 192
>X52008-1|CAA36257.1| 452|Homo sapiens inhibitory glycine receptor
protein.
Length = 452
Score = 48.8 bits (111), Expect = 3e-05
Identities = 38/135 (28%), Positives = 60/135 (44%), Gaps = 8/135 (5%)
Frame = +2
Query: 164 YDRESPPDSK-IVVNLTLHL---RHASIRESESTVRMLAGLQMNWIDKRLSWNAGEWGCS 331
YD P+ K VN+T ++ S+ E+ R+ L+ W D RL+++
Sbjct: 58 YDARIRPNFKGPPVNVTCNIFINSFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPDDSL 117
Query: 332 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLD 499
S + +W+PD+ N D R+S NG V + RL ++ M L
Sbjct: 118 DLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLK 177
Query: 500 NWPNDMQTCTFKFGS 544
N+P D+QTCT + S
Sbjct: 178 NFPMDVQTCTMQLES 192
>U77731-1|AAB38272.1| 360|Homo sapiens glycine receptor alpha 2
subunit protein.
Length = 360
Score = 48.8 bits (111), Expect = 3e-05
Identities = 38/135 (28%), Positives = 60/135 (44%), Gaps = 8/135 (5%)
Frame = +2
Query: 164 YDRESPPDSK-IVVNLTLHL---RHASIRESESTVRMLAGLQMNWIDKRLSWNAGEWGCS 331
YD P+ K VN+T ++ S+ E+ R+ L+ W D RL+++
Sbjct: 58 YDARIRPNFKGPPVNVTCNIFINSFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPDDSL 117
Query: 332 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLD 499
S + +W+PD+ N D R+S NG V + RL ++ M L
Sbjct: 118 DLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLK 177
Query: 500 NWPNDMQTCTFKFGS 544
N+P D+QTCT + S
Sbjct: 178 NFPMDVQTCTMQLES 192
>BC032864-1|AAH32864.1| 452|Homo sapiens glycine receptor, alpha 2
protein.
Length = 452
Score = 48.8 bits (111), Expect = 3e-05
Identities = 38/135 (28%), Positives = 60/135 (44%), Gaps = 8/135 (5%)
Frame = +2
Query: 164 YDRESPPDSK-IVVNLTLHL---RHASIRESESTVRMLAGLQMNWIDKRLSWNAGEWGCS 331
YD P+ K VN+T ++ S+ E+ R+ L+ W D RL+++
Sbjct: 58 YDARIRPNFKGPPVNVTCNIFINSFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPDDSL 117
Query: 332 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLD 499
S + +W+PD+ N D R+S NG V + RL ++ M L
Sbjct: 118 DLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLK 177
Query: 500 NWPNDMQTCTFKFGS 544
N+P D+QTCT + S
Sbjct: 178 NFPMDVQTCTMQLES 192
>BC028629-1|AAH28629.1| 492|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 3 protein.
Length = 492
Score = 48.8 bits (111), Expect = 3e-05
Identities = 34/150 (22%), Positives = 66/150 (44%), Gaps = 7/150 (4%)
Frame = +2
Query: 116 ENATSLSLMIDSLLATYDRESPP---DSKIVVNLTLHLRH-ASIRESESTVRMLAGLQMN 283
+N T + ++D LL YD P D+ V +++ + +++ + +
Sbjct: 62 DNITIFTRILDRLLDGYDNRLRPGLGDAVTEVKTDIYVTSFGPVSDTDMEYTIDVFFRQT 121
Query: 284 WIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSW 454
W D+RL ++ + + ++W PD N + A + R+ +NG++ +
Sbjct: 122 WHDERLKFDGPMKILPLNNLLASKIWTPDTFFHNGKKSVAHNMTTPNKLLRLVDNGTLPY 181
Query: 455 IKRLDISTPISMQLDNWPNDMQTCTFKFGS 544
RL I M L+++P D+ C KFGS
Sbjct: 182 TMRLTIHAECPMHLEDFPMDVHACPLKFGS 211
>AY437083-1|AAR87842.1| 452|Homo sapiens glycine receptor alpha2
subunit A protein.
Length = 452
Score = 48.8 bits (111), Expect = 3e-05
Identities = 38/135 (28%), Positives = 60/135 (44%), Gaps = 8/135 (5%)
Frame = +2
Query: 164 YDRESPPDSK-IVVNLTLHL---RHASIRESESTVRMLAGLQMNWIDKRLSWNAGEWGCS 331
YD P+ K VN+T ++ S+ E+ R+ L+ W D RL+++
Sbjct: 58 YDARIRPNFKGPPVNVTCNIFINSFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPDDSL 117
Query: 332 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLD 499
S + +W+PD+ N D R+S NG V + RL ++ M L
Sbjct: 118 DLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLK 177
Query: 500 NWPNDMQTCTFKFGS 544
N+P D+QTCT + S
Sbjct: 178 NFPMDVQTCTMQLES 192
>AJ003080-1|CAA05853.1| 238|Homo sapiens serotonin receptor
protein.
Length = 238
Score = 48.8 bits (111), Expect = 3e-05
Identities = 25/93 (26%), Positives = 44/93 (47%), Gaps = 1/93 (1%)
Frame = +2
Query: 284 WIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVSWIK 460
W D+ L WN ++ T L + ++ +W PD+++ + + G V K
Sbjct: 90 WTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKSPNIPYVYIRHQGEVQNYK 149
Query: 461 RLDISTPISMQLDNWPNDMQTCTFKFGSRMHNS 559
L + T S+ + N+P D+Q C+ F S +H S
Sbjct: 150 PLQVVTACSLDIYNFPFDVQNCSLTFTSWLHTS 182
>AF053495-1|AAC35290.1| 452|Homo sapiens glycine receptor alpha 2
subunit protein.
Length = 452
Score = 48.8 bits (111), Expect = 3e-05
Identities = 38/135 (28%), Positives = 60/135 (44%), Gaps = 8/135 (5%)
Frame = +2
Query: 164 YDRESPPDSK-IVVNLTLHL---RHASIRESESTVRMLAGLQMNWIDKRLSWNAGEWGCS 331
YD P+ K VN+T ++ S+ E+ R+ L+ W D RL+++
Sbjct: 58 YDARIRPNFKGPPVNVTCNIFINSFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPDDSL 117
Query: 332 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLD 499
S + +W+PD+ N D R+S NG V + RL ++ M L
Sbjct: 118 DLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLK 177
Query: 500 NWPNDMQTCTFKFGS 544
N+P D+QTCT + S
Sbjct: 178 NFPMDVQTCTMQLES 192
>S62908-1|AAB27279.1| 492|Homo sapiens gamma-aminobutyric acidA
receptor alpha 3 subunit protein.
Length = 492
Score = 48.4 bits (110), Expect = 3e-05
Identities = 34/150 (22%), Positives = 66/150 (44%), Gaps = 7/150 (4%)
Frame = +2
Query: 116 ENATSLSLMIDSLLATYDRESPP---DSKIVVNLTLHLRH-ASIRESESTVRMLAGLQMN 283
+N T + ++D LL YD P D+ V +++ + +++ + +
Sbjct: 62 DNITIFTRILDRLLDGYDNRLRPGLGDAVTEVKTDIYVTSFGPVSDTDMEYTIDVFFRQT 121
Query: 284 WIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSW 454
W D+RL ++ + + ++W PD N + A + R+ +NG++ +
Sbjct: 122 WHDERLKFDGPMKILPLNNLLASKIWTPDTFFHNGKKSVAHNMTTPNKLLRLVDNGTLLY 181
Query: 455 IKRLDISTPISMQLDNWPNDMQTCTFKFGS 544
RL I M L+++P D+ C KFGS
Sbjct: 182 TMRLTIHAECPMHLEDFPMDVHACPLKFGS 211
>BC096083-1|AAH96083.1| 198|Homo sapiens CHRNB4 protein protein.
Length = 198
Score = 48.4 bits (110), Expect = 3e-05
Identities = 31/115 (26%), Positives = 54/115 (46%), Gaps = 8/115 (6%)
Frame = +2
Query: 92 AIASAAECENATSLSLMIDSLL--ATYDRESPP--DSKIVVNLTLHLRHA---SIRESES 250
A+ C A + ++D LL Y+ P S ++++ L L A S+ E E
Sbjct: 14 ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQ 73
Query: 251 TVRMLAGLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDY 412
+ L+ W D RL+WN+ + G + + ++R+W PD+VL N + T +
Sbjct: 74 IMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNKSLRTGSTW 128
>BC096081-1|AAH96081.1| 198|Homo sapiens CHRNB4 protein protein.
Length = 198
Score = 48.4 bits (110), Expect = 3e-05
Identities = 31/115 (26%), Positives = 54/115 (46%), Gaps = 8/115 (6%)
Frame = +2
Query: 92 AIASAAECENATSLSLMIDSLL--ATYDRESPP--DSKIVVNLTLHLRHA---SIRESES 250
A+ C A + ++D LL Y+ P S ++++ L L A S+ E E
Sbjct: 14 ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQ 73
Query: 251 TVRMLAGLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDY 412
+ L+ W D RL+WN+ + G + + ++R+W PD+VL N + T +
Sbjct: 74 IMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNKSLRTGSTW 128
>BC033801-1|AAH33801.1| 452|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, delta protein.
Length = 452
Score = 48.4 bits (110), Expect = 3e-05
Identities = 40/147 (27%), Positives = 62/147 (42%), Gaps = 7/147 (4%)
Frame = +2
Query: 143 IDSLLATYDRESPPD-SKIVVNLTLHLRHASI---RESESTVRMLAGLQMNWIDKRLSWN 310
+D L+A Y R P VN+ L L ASI E+ M L +W D RLS+N
Sbjct: 44 LDGLIAGYARNFRPGIGGPPVNVALALEVASIDHISEANMEYTMTVFLHQSWRDSRLSYN 103
Query: 311 AGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTP 481
++LW PD ++NA + D + R+ +G + + R+ +
Sbjct: 104 HTNETLGLDSRFVDKLWLPDTFIVNAKSAWFHDVTVENKLIRLQPDGVILYSIRITSTVA 163
Query: 482 ISMQLDNWPNDMQTCTFKFGSRMHNSD 562
M L +P D Q C S ++S+
Sbjct: 164 CDMDLAKYPMDEQECMLDLESYGYSSE 190
>AL391845-4|CAI15436.1| 452|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, delta protein.
Length = 452
Score = 48.4 bits (110), Expect = 3e-05
Identities = 40/147 (27%), Positives = 62/147 (42%), Gaps = 7/147 (4%)
Frame = +2
Query: 143 IDSLLATYDRESPPD-SKIVVNLTLHLRHASI---RESESTVRMLAGLQMNWIDKRLSWN 310
+D L+A Y R P VN+ L L ASI E+ M L +W D RLS+N
Sbjct: 44 LDGLIAGYARNFRPGIGGPPVNVALALEVASIDHISEANMEYTMTVFLHQSWRDSRLSYN 103
Query: 311 AGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTP 481
++LW PD ++NA + D + R+ +G + + R+ +
Sbjct: 104 HTNETLGLDSRFVDKLWLPDTFIVNAKSAWFHDVTVENKLIRLQPDGVILYSIRITSTVA 163
Query: 482 ISMQLDNWPNDMQTCTFKFGSRMHNSD 562
M L +P D Q C S ++S+
Sbjct: 164 CDMDLAKYPMDEQECMLDLESYGYSSE 190
>AF166361-1|AAG12455.1| 492|Homo sapiens GABA receptor subunit
alpha 3 protein.
Length = 492
Score = 48.4 bits (110), Expect = 3e-05
Identities = 34/150 (22%), Positives = 66/150 (44%), Gaps = 7/150 (4%)
Frame = +2
Query: 116 ENATSLSLMIDSLLATYDRESPP---DSKIVVNLTLHLRH-ASIRESESTVRMLAGLQMN 283
+N T + ++D LL YD P D+ V +++ + +++ + +
Sbjct: 62 DNITIFTRILDRLLDGYDNRLRPGLGDAVTEVKTDIYVTSFGPVSDTDMEYTIDVFFRQT 121
Query: 284 WIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSW 454
W D+RL ++ + + ++W PD N + A + R+ +NG++ +
Sbjct: 122 WHDERLKFDGPMKILPLNNLLASKIWTPDTFFHNGKKSVAHNMTTPNKLLRLVDNGTLLY 181
Query: 455 IKRLDISTPISMQLDNWPNDMQTCTFKFGS 544
RL I M L+++P D+ C KFGS
Sbjct: 182 TMRLTIHAECPMHLEDFPMDVHACPLKFGS 211
>AF016917-1|AAB70007.1| 452|Homo sapiens GABA-A receptor delta
subunit protein.
Length = 452
Score = 48.4 bits (110), Expect = 3e-05
Identities = 40/147 (27%), Positives = 62/147 (42%), Gaps = 7/147 (4%)
Frame = +2
Query: 143 IDSLLATYDRESPPD-SKIVVNLTLHLRHASI---RESESTVRMLAGLQMNWIDKRLSWN 310
+D L+A Y R P VN+ L L ASI E+ M L +W D RLS+N
Sbjct: 44 LDGLIAGYARNFRPGIGGPPVNVALALEVASIDHISEANMEYTMTVFLHQSWRDSRLSYN 103
Query: 311 AGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTP 481
++LW PD ++NA + D + R+ +G + + R+ +
Sbjct: 104 HTNETLGLDSRFVDKLWLPDTFIVNAKSAWFHDVTVENKLIRLQPDGVILYSIRITSTVA 163
Query: 482 ISMQLDNWPNDMQTCTFKFGSRMHNSD 562
M L +P D Q C S ++S+
Sbjct: 164 CDMDLAKYPMDEQECMLDLESYGYSSE 190
>U30461-1|AAB52519.1| 554|Homo sapiens GABAA receptor subunit
alpha4 protein.
Length = 554
Score = 48.0 bits (109), Expect = 4e-05
Identities = 40/156 (25%), Positives = 64/156 (41%), Gaps = 7/156 (4%)
Frame = +2
Query: 140 MIDSLLATYD-RESPPDSKIVVNLTLHLRHAS---IRESESTVRMLAGLQMNWIDKRLSW 307
++DSLL YD R P V + + S + + E M + WIDKRL +
Sbjct: 51 ILDSLLDGYDNRLRPGFGGPVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWIDKRLKY 110
Query: 308 NAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRA---RVSNNGSVSWIKRLDIST 478
+ + ++W PD N + + + R+ NG++ + RL IS
Sbjct: 111 DGPIEILRLNNMMVTKVWTPDTFFRNGKKSVSHNMTAPNKLFRIMRNGTILYTMRLTISA 170
Query: 479 PISMQLDNWPNDMQTCTFKFGSRMHNSDXMDFVIDK 586
M+L ++P D C KFGS + M + K
Sbjct: 171 ECPMRLVDFPMDGHACPLKFGSYAYPKSEMIYTWTK 206
>BC035055-1|AAH35055.1| 554|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 4 protein.
Length = 554
Score = 48.0 bits (109), Expect = 4e-05
Identities = 40/156 (25%), Positives = 64/156 (41%), Gaps = 7/156 (4%)
Frame = +2
Query: 140 MIDSLLATYD-RESPPDSKIVVNLTLHLRHAS---IRESESTVRMLAGLQMNWIDKRLSW 307
++DSLL YD R P V + + S + + E M + WIDKRL +
Sbjct: 51 ILDSLLDGYDNRLRPGFGGPVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWIDKRLKY 110
Query: 308 NAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRA---RVSNNGSVSWIKRLDIST 478
+ + ++W PD N + + + R+ NG++ + RL IS
Sbjct: 111 DGPIEILRLNNMMVTKVWTPDTFFRNGKKSVSHNMTAPNKLFRIMRNGTILYTMRLTISA 170
Query: 479 PISMQLDNWPNDMQTCTFKFGSRMHNSDXMDFVIDK 586
M+L ++P D C KFGS + M + K
Sbjct: 171 ECPMRLVDFPMDGHACPLKFGSYAYPKSEMIYTWTK 206
>S82612-1|AAB37533.2| 478|Homo sapiens 5-hydroxytryptamine type 3AS
receptor subunit protein.
Length = 478
Score = 47.6 bits (108), Expect = 6e-05
Identities = 24/91 (26%), Positives = 43/91 (47%), Gaps = 1/91 (1%)
Frame = +2
Query: 284 WIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVSWIK 460
W D+ L WN ++ T L + ++ +W PD+++ + + G V K
Sbjct: 90 WTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINELVDVGKSPNIPYVYIRHQGEVQNYK 149
Query: 461 RLDISTPISMQLDNWPNDMQTCTFKFGSRMH 553
L + T S+ + N+P D+Q C+ F S +H
Sbjct: 150 PLQVVTACSLDIYNFPFDVQNCSLTFTSWLH 180
>S82769-1|AAB39369.1| 467|Homo sapiens GABAA receptor gamma 3
subunit protein.
Length = 467
Score = 47.2 bits (107), Expect = 8e-05
Identities = 37/172 (21%), Positives = 72/172 (41%), Gaps = 7/172 (4%)
Frame = +2
Query: 125 TSLSLMIDSLLATYDRESPPDSKI---VVNLTLHLRHAS-IRESESTVRMLAGLQMNWID 292
T ++L+++ LL YD++ PD I V+++ +++ + ++ W D
Sbjct: 45 TDVTLILNKLLREYDKKLRPDIGIKPTVIDVDIYVNSIGPVSSINMEYQIDIFFAQTWTD 104
Query: 293 KRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKR 463
RL +N+ + +W PD + N+ A R+ N+G + + R
Sbjct: 105 SRLRFNSTMKILTLNSNMVGLIWIPDTIFRNSKTAEAHWITTPNQLLRIWNDGKILYTLR 164
Query: 464 LDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDXMDFVIDKRIYSMFESGAW 619
L I+ +QL N+P D +C F S + + M + K + +W
Sbjct: 165 LTINAECQLQLHNFPMDEHSCPLIFSSYGYPKEEMIYRWRKNSVEAADQKSW 216
>D49394-1|BAA08387.1| 478|Homo sapiens serotonin 5-HT3 receptor
protein.
Length = 478
Score = 47.2 bits (107), Expect = 8e-05
Identities = 24/91 (26%), Positives = 43/91 (47%), Gaps = 1/91 (1%)
Frame = +2
Query: 284 WIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVSWIK 460
W D+ L WN ++ T L + ++ +W PD+++ + + G V K
Sbjct: 90 WTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKSPNIPYVYIRHQGEVQNYK 149
Query: 461 RLDISTPISMQLDNWPNDMQTCTFKFGSRMH 553
L + T S+ + N+P D+Q C+ F S +H
Sbjct: 150 PLQVVTACSLDIYNFPFDVQNCSLTFTSWLH 180
>BT007204-1|AAP35868.1| 484|Homo sapiens 5-hydroxytryptamine
(serotonin) receptor 3A protein.
Length = 484
Score = 47.2 bits (107), Expect = 8e-05
Identities = 24/91 (26%), Positives = 43/91 (47%), Gaps = 1/91 (1%)
Frame = +2
Query: 284 WIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVSWIK 460
W D+ L WN ++ T L + ++ +W PD+++ + + G V K
Sbjct: 96 WTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKSPNIPYVYIRHQGEVQNYK 155
Query: 461 RLDISTPISMQLDNWPNDMQTCTFKFGSRMH 553
L + T S+ + N+P D+Q C+ F S +H
Sbjct: 156 PLQVVTACSLDIYNFPFDVQNCSLTFTSWLH 186
>BC022449-1|AAH22449.1| 474|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, beta 1 protein.
Length = 474
Score = 47.2 bits (107), Expect = 8e-05
Identities = 42/169 (24%), Positives = 72/169 (42%), Gaps = 7/169 (4%)
Frame = +2
Query: 89 CAIASAAECENATSLSLMIDSLLATYDRESPPD-SKIVVNLTLHLRHASI---RESESTV 256
C S E N + + +D LL YD PD V++ + + ASI E
Sbjct: 23 CCAHSTNEPSNMSYVKETVDRLLKGYDIRLRPDFGGPPVDVGMRIDVASIDMVSEVNMDY 82
Query: 257 RMLAGLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---AR 427
+ Q +W DKRLS++ + +++L PD LN + ++ R
Sbjct: 83 TLTMYFQQSWKDKRLSYSGIPLNLTLDNRVADQLCVPDTYFLNDKKSFVHGVTVKNRMIR 142
Query: 428 VSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDXMDF 574
+ +G+V + R+ + M L +P D Q CT + S + +D ++F
Sbjct: 143 LHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEF 191
>BC004453-1|AAH04453.2| 478|Homo sapiens 5-hydroxytryptamine
(serotonin) receptor 3A protein.
Length = 478
Score = 47.2 bits (107), Expect = 8e-05
Identities = 24/91 (26%), Positives = 43/91 (47%), Gaps = 1/91 (1%)
Frame = +2
Query: 284 WIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVSWIK 460
W D+ L WN ++ T L + ++ +W PD+++ + + G V K
Sbjct: 90 WTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKSPNIPYVYIRHQGEVQNYK 149
Query: 461 RLDISTPISMQLDNWPNDMQTCTFKFGSRMH 553
L + T S+ + N+P D+Q C+ F S +H
Sbjct: 150 PLQVVTACSLDIYNFPFDVQNCSLTFTSWLH 180
>BC002354-1|AAH02354.1| 478|Homo sapiens 5-hydroxytryptamine
(serotonin) receptor 3A protein.
Length = 478
Score = 47.2 bits (107), Expect = 8e-05
Identities = 24/91 (26%), Positives = 43/91 (47%), Gaps = 1/91 (1%)
Frame = +2
Query: 284 WIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVSWIK 460
W D+ L WN ++ T L + ++ +W PD+++ + + G V K
Sbjct: 90 WTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKSPNIPYVYIRHQGEVQNYK 149
Query: 461 RLDISTPISMQLDNWPNDMQTCTFKFGSRMH 553
L + T S+ + N+P D+Q C+ F S +H
Sbjct: 150 PLQVVTACSLDIYNFPFDVQNCSLTFTSWLH 180
>AJ005205-1|CAA06442.3| 478|Homo sapiens serotonin 3 receptor
protein.
Length = 478
Score = 47.2 bits (107), Expect = 8e-05
Identities = 24/91 (26%), Positives = 43/91 (47%), Gaps = 1/91 (1%)
Frame = +2
Query: 284 WIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVSWIK 460
W D+ L WN ++ T L + ++ +W PD+++ + + G V K
Sbjct: 90 WTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKSPNIPYVYIRHQGEVQNYK 149
Query: 461 RLDISTPISMQLDNWPNDMQTCTFKFGSRMH 553
L + T S+ + N+P D+Q C+ F S +H
Sbjct: 150 PLQVVTACSLDIYNFPFDVQNCSLTFTSWLH 180
>AJ003079-1|CAA05852.1| 478|Homo sapiens 5-hydroxytryptamine3
receptor protein.
Length = 478
Score = 47.2 bits (107), Expect = 8e-05
Identities = 24/91 (26%), Positives = 43/91 (47%), Gaps = 1/91 (1%)
Frame = +2
Query: 284 WIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVSWIK 460
W D+ L WN ++ T L + ++ +W PD+++ + + G V K
Sbjct: 90 WTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKSPNIPYVYIRHQGEVQNYK 149
Query: 461 RLDISTPISMQLDNWPNDMQTCTFKFGSRMH 553
L + T S+ + N+P D+Q C+ F S +H
Sbjct: 150 PLQVVTACSLDIYNFPFDVQNCSLTFTSWLH 180
>AJ003078-1|CAA05851.1| 510|Homo sapiens serotonin receptor
protein.
Length = 510
Score = 47.2 bits (107), Expect = 8e-05
Identities = 24/91 (26%), Positives = 43/91 (47%), Gaps = 1/91 (1%)
Frame = +2
Query: 284 WIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVSWIK 460
W D+ L WN ++ T L + ++ +W PD+++ + + G V K
Sbjct: 90 WTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKSPNIPYVYIRHQGEVQNYK 149
Query: 461 RLDISTPISMQLDNWPNDMQTCTFKFGSRMH 553
L + T S+ + N+P D+Q C+ F S +H
Sbjct: 150 PLQVVTACSLDIYNFPFDVQNCSLTFTSWLH 180
>AF498984-1|AAM21131.1| 478|Homo sapiens 5-hydroxytryptamine
receptor 3A protein.
Length = 478
Score = 47.2 bits (107), Expect = 8e-05
Identities = 24/91 (26%), Positives = 43/91 (47%), Gaps = 1/91 (1%)
Frame = +2
Query: 284 WIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVSWIK 460
W D+ L WN ++ T L + ++ +W PD+++ + + G V K
Sbjct: 90 WTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKSPNIPYVYIRHQGEVQNYK 149
Query: 461 RLDISTPISMQLDNWPNDMQTCTFKFGSRMH 553
L + T S+ + N+P D+Q C+ F S +H
Sbjct: 150 PLQVVTACSLDIYNFPFDVQNCSLTFTSWLH 180
>AF269144-1|AAF99698.1| 467|Homo sapiens GABAA receptor gamma 3
subunit protein.
Length = 467
Score = 47.2 bits (107), Expect = 8e-05
Identities = 37/172 (21%), Positives = 72/172 (41%), Gaps = 7/172 (4%)
Frame = +2
Query: 125 TSLSLMIDSLLATYDRESPPDSKI---VVNLTLHLRHAS-IRESESTVRMLAGLQMNWID 292
T ++L+++ LL YD++ PD I V+++ +++ + ++ W D
Sbjct: 45 TDVTLILNKLLREYDKKLRPDIGIKPTVIDVDIYVNSIGPVSSINMEYQIDIFFAQTWTD 104
Query: 293 KRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKR 463
RL +N+ + +W PD + N+ A R+ N+G + + R
Sbjct: 105 SRLRFNSTMKILTLNSNMVGLIWIPDTIFRNSKTAEAHWITTPNQLLRIWNDGKILYTLR 164
Query: 464 LDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDXMDFVIDKRIYSMFESGAW 619
L I+ +QL N+P D +C F S + + M + K + +W
Sbjct: 165 LTINAECQLQLHNFPMDEHSCPLIFSSYGYPKEEMIYRWRKNSVEAADQKSW 216
>AF228458-1|AAF63215.1| 449|Homo sapiens GABAA receptor gamma 3
subunit protein.
Length = 449
Score = 47.2 bits (107), Expect = 8e-05
Identities = 37/172 (21%), Positives = 72/172 (41%), Gaps = 7/172 (4%)
Frame = +2
Query: 125 TSLSLMIDSLLATYDRESPPDSKI---VVNLTLHLRHAS-IRESESTVRMLAGLQMNWID 292
T ++L+++ LL YD++ PD I V+++ +++ + ++ W D
Sbjct: 27 TDVTLILNKLLREYDKKLRPDIGIKPTVIDVDIYVNSIGPVSSINMEYQIDIFFAQTWTD 86
Query: 293 KRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKR 463
RL +N+ + +W PD + N+ A R+ N+G + + R
Sbjct: 87 SRLRFNSTMKILTLNSNMVGLIWIPDTIFRNSKTAEAHWITTPNQLLRIWNDGKILYTLR 146
Query: 464 LDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDXMDFVIDKRIYSMFESGAW 619
L I+ +QL N+P D +C F S + + M + K + +W
Sbjct: 147 LTINAECQLQLHNFPMDEHSCPLIFSSYGYPKEEMIYRWRKNSVEAADQKSW 198
>U95367-1|AAC51357.1| 440|Homo sapiens GABA-A receptor pi subunit
protein.
Length = 440
Score = 46.8 bits (106), Expect = 1e-04
Identities = 41/164 (25%), Positives = 77/164 (46%), Gaps = 9/164 (5%)
Frame = +2
Query: 110 ECENATSLSLM-IDSLLATYDRESPPD---SKIVVNLTLHLRH-ASIRESESTVRMLAGL 274
E + LSL ++L A Y++ P+ + + LTL + +SI ES L
Sbjct: 29 EVGRSDKLSLPGFENLTAGYNKFLRPNFGGEPVQIALTLDIASISSISESNMDYTATIYL 88
Query: 275 QMNWIDKRLSWNAGE-WGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNG 442
+ W+D+RL + + + LV E LW PD ++ + + + + R+ +NG
Sbjct: 89 RQRWMDQRLVFEGNKSFTLDARLV--EFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNG 146
Query: 443 SVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDXMDF 574
+V + R+ + +M L +P D QTC + S ++ + ++F
Sbjct: 147 TVLYALRITTTVACNMDLSKYPMDTQTCKLQLESWGYDGNDVEF 190
>BC109106-1|AAI09107.1| 440|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, pi protein.
Length = 440
Score = 46.8 bits (106), Expect = 1e-04
Identities = 41/164 (25%), Positives = 77/164 (46%), Gaps = 9/164 (5%)
Frame = +2
Query: 110 ECENATSLSLM-IDSLLATYDRESPPD---SKIVVNLTLHLRH-ASIRESESTVRMLAGL 274
E + LSL ++L A Y++ P+ + + LTL + +SI ES L
Sbjct: 29 EVGRSDKLSLPGFENLTAGYNKFLRPNFGGEPVQIALTLDIASISSISESNMDYTATIYL 88
Query: 275 QMNWIDKRLSWNAGE-WGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNG 442
+ W+D+RL + + + LV E LW PD ++ + + + + R+ +NG
Sbjct: 89 RQRWMDQRLVFEGNKSFTLDARLV--EFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNG 146
Query: 443 SVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDXMDF 574
+V + R+ + +M L +P D QTC + S ++ + ++F
Sbjct: 147 TVLYALRITTTVACNMDLSKYPMDTQTCKLQLESWGYDGNDVEF 190
>BC109105-1|AAI09106.1| 440|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, pi protein.
Length = 440
Score = 46.8 bits (106), Expect = 1e-04
Identities = 41/164 (25%), Positives = 77/164 (46%), Gaps = 9/164 (5%)
Frame = +2
Query: 110 ECENATSLSLM-IDSLLATYDRESPPD---SKIVVNLTLHLRH-ASIRESESTVRMLAGL 274
E + LSL ++L A Y++ P+ + + LTL + +SI ES L
Sbjct: 29 EVGRSDKLSLPGFENLTAGYNKFLRPNFGGEPVQIALTLDIASISSISESNMDYTATIYL 88
Query: 275 QMNWIDKRLSWNAGE-WGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNG 442
+ W+D+RL + + + LV E LW PD ++ + + + + R+ +NG
Sbjct: 89 RQRWMDQRLVFEGNKSFTLDARLV--EFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNG 146
Query: 443 SVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDXMDF 574
+V + R+ + +M L +P D QTC + S ++ + ++F
Sbjct: 147 TVLYALRITTTVACNMDLSKYPMDTQTCKLQLESWGYDGNDVEF 190
>BC074865-1|AAH74865.1| 440|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, pi protein.
Length = 440
Score = 46.8 bits (106), Expect = 1e-04
Identities = 41/164 (25%), Positives = 77/164 (46%), Gaps = 9/164 (5%)
Frame = +2
Query: 110 ECENATSLSLM-IDSLLATYDRESPPD---SKIVVNLTLHLRH-ASIRESESTVRMLAGL 274
E + LSL ++L A Y++ P+ + + LTL + +SI ES L
Sbjct: 29 EVGRSDKLSLPGFENLTAGYNKFLRPNFGGEPVQIALTLDIASISSISESNMDYTATIYL 88
Query: 275 QMNWIDKRLSWNAGE-WGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNG 442
+ W+D+RL + + + LV E LW PD ++ + + + + R+ +NG
Sbjct: 89 RQRWMDQRLVFEGNKSFTLDARLV--EFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNG 146
Query: 443 SVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDXMDF 574
+V + R+ + +M L +P D QTC + S ++ + ++F
Sbjct: 147 TVLYALRITTTVACNMDLSKYPMDTQTCKLQLESWGYDGNDVEF 190
>BC074810-1|AAH74810.1| 440|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, pi protein.
Length = 440
Score = 46.8 bits (106), Expect = 1e-04
Identities = 41/164 (25%), Positives = 77/164 (46%), Gaps = 9/164 (5%)
Frame = +2
Query: 110 ECENATSLSLM-IDSLLATYDRESPPD---SKIVVNLTLHLRH-ASIRESESTVRMLAGL 274
E + LSL ++L A Y++ P+ + + LTL + +SI ES L
Sbjct: 29 EVGRSDKLSLPGFENLTAGYNKFLRPNFGGEPVQIALTLDIASISSISESNMDYTATIYL 88
Query: 275 QMNWIDKRLSWNAGE-WGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNG 442
+ W+D+RL + + + LV E LW PD ++ + + + + R+ +NG
Sbjct: 89 RQRWMDQRLVFEGNKSFTLDARLV--EFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNG 146
Query: 443 SVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDXMDF 574
+V + R+ + +M L +P D QTC + S ++ + ++F
Sbjct: 147 TVLYALRITTTVACNMDLSKYPMDTQTCKLQLESWGYDGNDVEF 190
>AF009702-1|AAC24194.1| 440|Homo sapiens GABA-A receptor pi subunit
protein.
Length = 440
Score = 46.8 bits (106), Expect = 1e-04
Identities = 41/164 (25%), Positives = 77/164 (46%), Gaps = 9/164 (5%)
Frame = +2
Query: 110 ECENATSLSLM-IDSLLATYDRESPPD---SKIVVNLTLHLRH-ASIRESESTVRMLAGL 274
E + LSL ++L A Y++ P+ + + LTL + +SI ES L
Sbjct: 29 EVGRSDKLSLPGFENLTAGYNKFLRPNFGGEPVQIALTLDIASISSISESNMDYTATIYL 88
Query: 275 QMNWIDKRLSWNAGE-WGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNG 442
+ W+D+RL + + + LV E LW PD ++ + + + + R+ +NG
Sbjct: 89 RQRWMDQRLVFEGNKSFTLDARLV--EFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNG 146
Query: 443 SVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDXMDF 574
+V + R+ + +M L +P D QTC + S ++ + ++F
Sbjct: 147 TVLYALRITTTVACNMDLSKYPMDTQTCKLQLESWGYDGNDVEF 190
>BC109211-1|AAI09212.1| 632|Homo sapiens gamma-aminobutyric acid
(GABA) receptor, theta protein.
Length = 632
Score = 45.6 bits (103), Expect = 2e-04
Identities = 34/145 (23%), Positives = 60/145 (41%), Gaps = 7/145 (4%)
Frame = +2
Query: 113 CENATSLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAS-IRESESTVRMLAGLQM 280
C N + ++D +L+ YD P+ + + V +++++ I E +
Sbjct: 53 CANEAVVQKILDRVLSRYDVRLRPNFGGAPVPVRISIYVTSIEQISEMNMDYTITMFFHQ 112
Query: 281 NWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSN---NGSVS 451
W D RL++ + E+LW PD LN+ D + RV +G+V
Sbjct: 113 TWKDSRLAYYETTLNLTLDYRMHEKLWVPDCYFLNSKDAFVHDVTVENRVFQLHPDGTVR 172
Query: 452 WIKRLDISTPISMQLDNWPNDMQTC 526
+ RL + S+ L +P D Q C
Sbjct: 173 YGIRLTTTAACSLDLHKFPMDKQAC 197
>BC109210-1|AAI09211.1| 632|Homo sapiens gamma-aminobutyric acid
(GABA) receptor, theta protein.
Length = 632
Score = 45.6 bits (103), Expect = 2e-04
Identities = 34/145 (23%), Positives = 60/145 (41%), Gaps = 7/145 (4%)
Frame = +2
Query: 113 CENATSLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAS-IRESESTVRMLAGLQM 280
C N + ++D +L+ YD P+ + + V +++++ I E +
Sbjct: 53 CANEAVVQKILDRVLSRYDVRLRPNFGGAPVPVRISIYVTSIEQISEMNMDYTITMFFHQ 112
Query: 281 NWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSN---NGSVS 451
W D RL++ + E+LW PD LN+ D + RV +G+V
Sbjct: 113 TWKDSRLAYYETTLNLTLDYRMHEKLWVPDCYFLNSKDAFVHDVTVENRVFQLHPDGTVR 172
Query: 452 WIKRLDISTPISMQLDNWPNDMQTC 526
+ RL + S+ L +P D Q C
Sbjct: 173 YGIRLTTTAACSLDLHKFPMDKQAC 197
>AF189259-1|AAF70380.1| 632|Homo sapiens GABA-A receptor theta
subunit protein.
Length = 632
Score = 45.6 bits (103), Expect = 2e-04
Identities = 34/145 (23%), Positives = 60/145 (41%), Gaps = 7/145 (4%)
Frame = +2
Query: 113 CENATSLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAS-IRESESTVRMLAGLQM 280
C N + ++D +L+ YD P+ + + V +++++ I E +
Sbjct: 53 CANEAVVQKILDRVLSRYDVRLRPNFGGAPVPVRISIYVTSIEQISEMNMDYTITMFFHQ 112
Query: 281 NWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSN---NGSVS 451
W D RL++ + E+LW PD LN+ D + RV +G+V
Sbjct: 113 TWKDSRLAYYETTLNLTLDYRMHEKLWVPDCYFLNSKDAFVHDVTVENRVFQLHPDGTVR 172
Query: 452 WIKRLDISTPISMQLDNWPNDMQTC 526
+ RL + S+ L +P D Q C
Sbjct: 173 YGIRLTTTAACSLDLHKFPMDKQAC 197
>AF144648-1|AAD51172.1| 627|Homo sapiens GABA-A receptor theta
protein.
Length = 627
Score = 45.6 bits (103), Expect = 2e-04
Identities = 34/145 (23%), Positives = 60/145 (41%), Gaps = 7/145 (4%)
Frame = +2
Query: 113 CENATSLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAS-IRESESTVRMLAGLQM 280
C N + ++D +L+ YD P+ + + V +++++ I E +
Sbjct: 48 CANEAVVQKILDRVLSRYDVRLRPNFGGAPVPVRISIYVTSIEQISEMNMDYTITMFFHQ 107
Query: 281 NWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSN---NGSVS 451
W D RL++ + E+LW PD LN+ D + RV +G+V
Sbjct: 108 TWKDSRLAYYETTLNLTLDYRMHEKLWVPDCYFLNSKDAFVHDVTVENRVFQLHPDGTVR 167
Query: 452 WIKRLDISTPISMQLDNWPNDMQTC 526
+ RL + S+ L +P D Q C
Sbjct: 168 YGIRLTTTAACSLDLHKFPMDKQAC 192
>X52009-1|CAA36258.1| 449|Homo sapiens inhibitory glycine receptor
protein.
Length = 449
Score = 45.2 bits (102), Expect = 3e-04
Identities = 36/138 (26%), Positives = 59/138 (42%), Gaps = 4/138 (2%)
Frame = +2
Query: 230 SIRESESTVRMLAGLQMNWIDKRLSWNAGEWGCSTWLVSS-ERLWRPDVVLLNAAATTAG 406
SI E+ R+ L+ W D RL++N S + +W+PD+ N
Sbjct: 78 SIAETTMDYRVNIFLRQQWNDPRLAYNEYPDDSLDLDPSMLDSIWKPDLFFANEKGAHFH 137
Query: 407 DYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDXMDFV 577
+ R+S NG+V + R+ ++ M L N+P D+QTC + S +
Sbjct: 138 EITTDNKLLRISRNGNVLYSIRITLTLACPMDLKNFPMDVQTCIMQLES-------FGYT 190
Query: 578 IDKRIYSMFESGAWDVTD 631
++ I+ E GA V D
Sbjct: 191 MNDLIFEWQEQGAVQVAD 208
>BC114947-1|AAI14948.1| 457|Homo sapiens GLRA1 protein protein.
Length = 457
Score = 45.2 bits (102), Expect = 3e-04
Identities = 36/138 (26%), Positives = 59/138 (42%), Gaps = 4/138 (2%)
Frame = +2
Query: 230 SIRESESTVRMLAGLQMNWIDKRLSWNAGEWGCSTWLVSS-ERLWRPDVVLLNAAATTAG 406
SI E+ R+ L+ W D RL++N S + +W+PD+ N
Sbjct: 78 SIAETTMDYRVNIFLRQQWNDPRLAYNEYPDDSLDLDPSMLDSIWKPDLFFANEKGAHFH 137
Query: 407 DYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDXMDFV 577
+ R+S NG+V + R+ ++ M L N+P D+QTC + S +
Sbjct: 138 EITTDNKLLRISRNGNVLYSIRITLTLACPMDLKNFPMDVQTCIMQLES-------FGYT 190
Query: 578 IDKRIYSMFESGAWDVTD 631
++ I+ E GA V D
Sbjct: 191 MNDLIFEWQEQGAVQVAD 208
>BC074980-1|AAH74980.1| 449|Homo sapiens glycine receptor, alpha 1
(startle disease/hyperekplexia) protein.
Length = 449
Score = 45.2 bits (102), Expect = 3e-04
Identities = 36/138 (26%), Positives = 59/138 (42%), Gaps = 4/138 (2%)
Frame = +2
Query: 230 SIRESESTVRMLAGLQMNWIDKRLSWNAGEWGCSTWLVSS-ERLWRPDVVLLNAAATTAG 406
SI E+ R+ L+ W D RL++N S + +W+PD+ N
Sbjct: 78 SIAETTMDYRVNIFLRQQWNDPRLAYNEYPDDSLDLDPSMLDSIWKPDLFFANEKGAHFH 137
Query: 407 DYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDXMDFV 577
+ R+S NG+V + R+ ++ M L N+P D+QTC + S +
Sbjct: 138 EITTDNKLLRISRNGNVLYSIRITLTLACPMDLKNFPMDVQTCIMQLES-------FGYT 190
Query: 578 IDKRIYSMFESGAWDVTD 631
++ I+ E GA V D
Sbjct: 191 MNDLIFEWQEQGAVQVAD 208
>Z93848-1|CAI41994.1| 376|Homo sapiens glycine receptor, alpha 4
protein.
Length = 376
Score = 43.6 bits (98), Expect = 0.001
Identities = 37/135 (27%), Positives = 59/135 (43%), Gaps = 8/135 (5%)
Frame = +2
Query: 164 YDRESPPDSK-IVVNLTLHL---RHASIRESESTVRMLAGLQMNWIDKRLSWNAGEWGCS 331
YD P+ K VN+T ++ +SI ++ R+ L+ W D RLS+
Sbjct: 17 YDARIRPNFKGPPVNVTCNIFINSFSSITKTTMDYRVNVFLRQQWNDPRLSYREYPDDSL 76
Query: 332 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLD 499
S + +W+PD+ N + R+ NG+V + RL + M L
Sbjct: 77 DLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLILSCLMDLK 136
Query: 500 NWPNDMQTCTFKFGS 544
N+P D+QTCT + S
Sbjct: 137 NFPMDIQTCTMQLES 151
>AL049610-1|CAI42158.1| 376|Homo sapiens glycine receptor, alpha 4
protein.
Length = 376
Score = 43.6 bits (98), Expect = 0.001
Identities = 37/135 (27%), Positives = 59/135 (43%), Gaps = 8/135 (5%)
Frame = +2
Query: 164 YDRESPPDSK-IVVNLTLHL---RHASIRESESTVRMLAGLQMNWIDKRLSWNAGEWGCS 331
YD P+ K VN+T ++ +SI ++ R+ L+ W D RLS+
Sbjct: 17 YDARIRPNFKGPPVNVTCNIFINSFSSITKTTMDYRVNVFLRQQWNDPRLSYREYPDDSL 76
Query: 332 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLD 499
S + +W+PD+ N + R+ NG+V + RL + M L
Sbjct: 77 DLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLILSCLMDLK 136
Query: 500 NWPNDMQTCTFKFGS 544
N+P D+QTCT + S
Sbjct: 137 NFPMDIQTCTMQLES 151
>AB209359-1|BAD92596.1| 533|Homo sapiens cholinergic receptor,
nicotinic, alpha polypeptide 4 precursor variant
protein.
Length = 533
Score = 43.2 bits (97), Expect = 0.001
Identities = 26/95 (27%), Positives = 43/95 (45%), Gaps = 3/95 (3%)
Frame = +2
Query: 356 LWRPDVVLLNAAATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFK 535
LW +A A + +A + ++G V W + S+ + +P D Q CT K
Sbjct: 25 LWLCCCTFTSADGDFAVTHLTKAHLFHDGRVQWTPPAIYKSSCSIDVTFFPFDQQNCTMK 84
Query: 536 FGSRMHNSDXMDFV-IDKRI--YSMFESGAWDVTD 631
FGS ++ +D V + R+ +ESG W + D
Sbjct: 85 FGSWTYDKAKIDLVNMHSRVDQLDFWESGEWVIVD 119
>U93917-1|AAC39917.1| 449|Homo sapiens glycine receptor alpha 3
subunit protein.
Length = 449
Score = 42.7 bits (96), Expect = 0.002
Identities = 36/135 (26%), Positives = 59/135 (43%), Gaps = 8/135 (5%)
Frame = +2
Query: 164 YDRESPPDSK-IVVNLTLHL---RHASIRESESTVRMLAGLQMNWIDKRLSWNAGEWGCS 331
YD P+ K VN+T ++ SI E+ R+ L+ W D RL+++
Sbjct: 57 YDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPDDSL 116
Query: 332 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLD 499
S + +W+PD+ N + R+ NG+V + RL ++ M L
Sbjct: 117 DLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLK 176
Query: 500 NWPNDMQTCTFKFGS 544
N+P D+QTC + S
Sbjct: 177 NFPMDVQTCIMQLES 191
>BC036086-1|AAH36086.1| 464|Homo sapiens glycine receptor, alpha 3
protein.
Length = 464
Score = 42.7 bits (96), Expect = 0.002
Identities = 36/135 (26%), Positives = 59/135 (43%), Gaps = 8/135 (5%)
Frame = +2
Query: 164 YDRESPPDSK-IVVNLTLHL---RHASIRESESTVRMLAGLQMNWIDKRLSWNAGEWGCS 331
YD P+ K VN+T ++ SI E+ R+ L+ W D RL+++
Sbjct: 57 YDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPDDSL 116
Query: 332 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLD 499
S + +W+PD+ N + R+ NG+V + RL ++ M L
Sbjct: 117 DLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLK 176
Query: 500 NWPNDMQTCTFKFGS 544
N+P D+QTC + S
Sbjct: 177 NFPMDVQTCIMQLES 191
>AF017724-1|AAC39919.1| 465|Homo sapiens glycine receptor alpha 3
subunit protein.
Length = 465
Score = 42.7 bits (96), Expect = 0.002
Identities = 36/135 (26%), Positives = 59/135 (43%), Gaps = 8/135 (5%)
Frame = +2
Query: 164 YDRESPPDSK-IVVNLTLHL---RHASIRESESTVRMLAGLQMNWIDKRLSWNAGEWGCS 331
YD P+ K VN+T ++ SI E+ R+ L+ W D RL+++
Sbjct: 57 YDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPDDSL 116
Query: 332 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLD 499
S + +W+PD+ N + R+ NG+V + RL ++ M L
Sbjct: 117 DLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLK 176
Query: 500 NWPNDMQTCTFKFGS 544
N+P D+QTC + S
Sbjct: 177 NFPMDVQTCIMQLES 191
>BC096291-1|AAH96291.1| 556|Homo sapiens CHRNA4 protein protein.
Length = 556
Score = 42.3 bits (95), Expect = 0.002
Identities = 25/83 (30%), Positives = 42/83 (50%), Gaps = 7/83 (8%)
Frame = +2
Query: 404 GDYAL----RARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDXMD 571
GD+A+ +A + ++G V W + S+ + +P D Q CT KFGS ++ +D
Sbjct: 60 GDFAVTHLTKAHLFHDGRVQWTPPAIYKSSCSIDVTFFPFDQQNCTMKFGSWTYDKAKID 119
Query: 572 FV-IDKRI--YSMFESGAWDVTD 631
V + R+ +ESG W + D
Sbjct: 120 LVNMHSRVDQLDFWESGEWVIVD 142
>BC114967-1|AAI14968.1| 366|Homo sapiens GLRA1 protein protein.
Length = 366
Score = 41.9 bits (94), Expect = 0.003
Identities = 32/124 (25%), Positives = 53/124 (42%), Gaps = 4/124 (3%)
Frame = +2
Query: 272 LQMNWIDKRLSWNAGEWGCSTWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNN 439
L+ W D RL++N S + +W+PD+ N + R+S N
Sbjct: 9 LRQQWNDPRLAYNEYPDDSLDLDPSMLDSIWKPDLFFANEKGAHFHEITTDNKLLRISRN 68
Query: 440 GSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDXMDFVIDKRIYSMFESGAW 619
G+V + R+ ++ M L N+P D+QTC + S + ++ I+ E GA
Sbjct: 69 GNVLYSIRITLTLACPMDLKNFPMDVQTCIMQLES-------FGYTMNDLIFEWQEQGAV 121
Query: 620 DVTD 631
V D
Sbjct: 122 QVAD 125
>BC031087-1|AAH31087.1| 465|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, gamma 1 protein.
Length = 465
Score = 41.5 bits (93), Expect = 0.004
Identities = 37/172 (21%), Positives = 73/172 (42%), Gaps = 9/172 (5%)
Frame = +2
Query: 131 LSLMIDSLLATYDRESPPDSKI---VVNLTLHLRHASIRES---ESTVRMLAGLQMNWID 292
++ +++SLL YD + PD + V+ +++ + E T+ ++ W D
Sbjct: 64 ITQILNSLLQGYDNKLRPDIGVRPTVIETDVYVNSIGPVDPINMEYTIDII--FAQTWFD 121
Query: 293 KRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKR 463
RL +N+ ++W PD N+ + A R+ N+G V + R
Sbjct: 122 SRLKFNSTMKVLMLNSNMVGKIWIPDTFFRNSRKSDAHWITTPNRLLRIWNDGRVLYTLR 181
Query: 464 LDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDXMDFVIDKRIYSMFESGAW 619
L I+ +QL N+P D +C +F S + + +++ K + + W
Sbjct: 182 LTINAECYLQLHNFPMDEHSCPLEFSSYGYPKNEIEYKWKKPSVEVADPKYW 233
>BC074795-1|AAH74795.1| 467|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, gamma 2 protein.
Length = 467
Score = 40.7 bits (91), Expect = 0.007
Identities = 33/145 (22%), Positives = 61/145 (42%), Gaps = 7/145 (4%)
Frame = +2
Query: 131 LSLMIDSLLATYDRESPPDSKIVVNLTLHLRHASIRESESTVRMLAGLQM----NWIDKR 298
+++++++LL YD + PD + L + + + + M + + W D+R
Sbjct: 66 VTVILNNLLEGYDNKLRPDIGVKPTLIHTDMYVNSIGPVNAINMEYTIDIFFAQTWYDRR 125
Query: 299 LSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYAL---RARVSNNGSVSWIKRLD 469
L +N+ ++W PD N+ A R+ N+G V + RL
Sbjct: 126 LKFNSTIKVLRLNSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYTLRLT 185
Query: 470 ISTPISMQLDNWPNDMQTCTFKFGS 544
I +QL N+P D +C +F S
Sbjct: 186 IDAECQLQLHNFPMDEHSCPLEFSS 210
>BC069348-1|AAH69348.1| 467|Homo sapiens gamma-aminobutyric acid A
receptor, gamma 2, isoform 2 precursor protein.
Length = 467
Score = 40.7 bits (91), Expect = 0.007
Identities = 33/145 (22%), Positives = 61/145 (42%), Gaps = 7/145 (4%)
Frame = +2
Query: 131 LSLMIDSLLATYDRESPPDSKIVVNLTLHLRHASIRESESTVRMLAGLQM----NWIDKR 298
+++++++LL YD + PD + L + + + + M + + W D+R
Sbjct: 66 VTVILNNLLEGYDNKLRPDIGVKPTLIHTDMYVNSIGPVNAINMEYTIDIFFAQTWYDRR 125
Query: 299 LSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYAL---RARVSNNGSVSWIKRLD 469
L +N+ ++W PD N+ A R+ N+G V + RL
Sbjct: 126 LKFNSTIKVLRLNSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYTLRLT 185
Query: 470 ISTPISMQLDNWPNDMQTCTFKFGS 544
I +QL N+P D +C +F S
Sbjct: 186 IDAECQLQLHNFPMDEHSCPLEFSS 210
>BC059389-1|AAH59389.1| 475|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, gamma 2 protein.
Length = 475
Score = 40.7 bits (91), Expect = 0.007
Identities = 33/145 (22%), Positives = 61/145 (42%), Gaps = 7/145 (4%)
Frame = +2
Query: 131 LSLMIDSLLATYDRESPPDSKIVVNLTLHLRHASIRESESTVRMLAGLQM----NWIDKR 298
+++++++LL YD + PD + L + + + + M + + W D+R
Sbjct: 66 VTVILNNLLEGYDNKLRPDIGVKPTLIHTDMYVNSIGPVNAINMEYTIDIFFAQTWYDRR 125
Query: 299 LSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYAL---RARVSNNGSVSWIKRLD 469
L +N+ ++W PD N+ A R+ N+G V + RL
Sbjct: 126 LKFNSTIKVLRLNSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYTLRLT 185
Query: 470 ISTPISMQLDNWPNDMQTCTFKFGS 544
I +QL N+P D +C +F S
Sbjct: 186 IDAECQLQLHNFPMDEHSCPLEFSS 210
>AF165124-1|AAD50273.1| 467|Homo sapiens gamma-aminobutyric acid A
receptor gamma 2 protein.
Length = 467
Score = 40.7 bits (91), Expect = 0.007
Identities = 33/145 (22%), Positives = 61/145 (42%), Gaps = 7/145 (4%)
Frame = +2
Query: 131 LSLMIDSLLATYDRESPPDSKIVVNLTLHLRHASIRESESTVRMLAGLQM----NWIDKR 298
+++++++LL YD + PD + L + + + + M + + W D+R
Sbjct: 66 VTVILNNLLEGYDNKLRPDIGVKPTLIHTDMYVNSIGPVNAINMEYTIDIFFAQTWYDRR 125
Query: 299 LSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYAL---RARVSNNGSVSWIKRLD 469
L +N+ ++W PD N+ A R+ N+G V + RL
Sbjct: 126 LKFNSTIKVLRLNSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYTLRLT 185
Query: 470 ISTPISMQLDNWPNDMQTCTFKFGS 544
I +QL N+P D +C +F S
Sbjct: 186 IDAECQLQLHNFPMDEHSCPLEFSS 210
>X15376-1|CAA33437.1| 467|Homo sapiens GABA-A receptor gamma 2
subunit protein.
Length = 467
Score = 39.9 bits (89), Expect = 0.012
Identities = 35/147 (23%), Positives = 66/147 (44%), Gaps = 9/147 (6%)
Frame = +2
Query: 131 LSLMIDSLLATYDRESPPDSKI---VVNLTLHLRH---ASIRESESTVRMLAGLQMNWID 292
+++++++LL YD + PD + +++ +++ + E T+ + QM W D
Sbjct: 66 VTVILNNLLEGYDNKLRPDIGVKPTLIHTDMYVNSIGPVNAINMEYTIDIFFA-QM-WYD 123
Query: 293 KRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYAL---RARVSNNGSVSWIKR 463
+RL +N+ ++W PD N+ A R+ N+G V + R
Sbjct: 124 RRLKFNSTIKVLRLNSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYSLR 183
Query: 464 LDISTPISMQLDNWPNDMQTCTFKFGS 544
L I +QL N+P D +C +F S
Sbjct: 184 LTIDAECQLQLHNFPMDEHSCPLEFSS 210
>AK093764-1|BAC04222.1| 360|Homo sapiens protein ( Homo sapiens
cDNA FLJ36445 fis, clone THYMU2013047. ).
Length = 360
Score = 33.1 bits (72), Expect = 1.3
Identities = 24/70 (34%), Positives = 35/70 (50%), Gaps = 4/70 (5%)
Frame = -1
Query: 427 TGAESVVPGGGCSRV*QYHVRPPQAF----RGHQPSAAAPFPCVPTQSFVDPIHLKTCQH 260
+G ES P + Q + PP+ F RG++P+A P P+ S+ DP K C+H
Sbjct: 37 SGEESTSPEQA-QTLGQDSLGPPEHFQGGPRGNEPAAHPPRWSTPS-SYEDPAGGKHCEH 94
Query: 259 PHGGLGLTNA 230
P GL + A
Sbjct: 95 PISGLEVLEA 104
>S56526-1|AAB19910.2| 138|Homo sapiens T cell receptor alpha chain
variable protein.
Length = 138
Score = 30.7 bits (66), Expect = 7.1
Identities = 15/40 (37%), Positives = 21/40 (52%)
Frame = -1
Query: 283 IHLKTCQHPHGGLGLTNASMPQMQGQVDYDFGVGGRLPIV 164
+H+ Q H G+ L A MPQ G + FG G RL ++
Sbjct: 94 LHITASQPSHAGIYLCGADMPQ-TGANNLFFGTGTRLTVI 132
>BC146774-1|AAI46775.1| 1114|Homo sapiens GPR124 protein protein.
Length = 1114
Score = 30.7 bits (66), Expect = 7.1
Identities = 16/55 (29%), Positives = 26/55 (47%), Gaps = 1/55 (1%)
Frame = +2
Query: 305 WNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNN-GSVSWIKRL 466
W +GEW C+ + + ++V+L T+ Y RV+NN G W + L
Sbjct: 314 WASGEWECTVSMAQGNASKKVEIVVLE----TSASYCPAERVANNRGDFRWPRTL 364
>AY181242-1|AAO27354.1| 1331|Homo sapiens G protein-coupled receptor
124 protein.
Length = 1331
Score = 30.7 bits (66), Expect = 7.1
Identities = 16/55 (29%), Positives = 26/55 (47%), Gaps = 1/55 (1%)
Frame = +2
Query: 305 WNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNN-GSVSWIKRL 466
W +GEW C+ + + ++V+L T+ Y RV+NN G W + L
Sbjct: 314 WASGEWECTVSMAQGNASKKVEIVVLE----TSASYCPAERVANNRGDFRWPRTL 364
>AK074099-1|BAB84925.1| 1310|Homo sapiens FLJ00170 protein protein.
Length = 1310
Score = 30.7 bits (66), Expect = 7.1
Identities = 16/55 (29%), Positives = 26/55 (47%), Gaps = 1/55 (1%)
Frame = +2
Query: 305 WNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNN-GSVSWIKRL 466
W +GEW C+ + + ++V+L T+ Y RV+NN G W + L
Sbjct: 293 WASGEWECTVSMAQGNASKKVEIVVLE----TSASYCPAERVANNRGDFRWPRTL 343
>AF378755-1|AAL11992.1| 1331|Homo sapiens tumor endothelial marker 5
precursor protein.
Length = 1331
Score = 30.7 bits (66), Expect = 7.1
Identities = 16/55 (29%), Positives = 26/55 (47%), Gaps = 1/55 (1%)
Frame = +2
Query: 305 WNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNN-GSVSWIKRL 466
W +GEW C+ + + ++V+L T+ Y RV+NN G W + L
Sbjct: 314 WASGEWECTVSMAQGNASKKVEIVVLE----TSASYCPAERVANNRGDFRWPRTL 364
>AB040964-1|BAA96055.2| 1206|Homo sapiens KIAA1531 protein protein.
Length = 1206
Score = 30.7 bits (66), Expect = 7.1
Identities = 16/55 (29%), Positives = 26/55 (47%), Gaps = 1/55 (1%)
Frame = +2
Query: 305 WNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNN-GSVSWIKRL 466
W +GEW C+ + + ++V+L T+ Y RV+NN G W + L
Sbjct: 406 WASGEWECTVSMAQGNASKKVEIVVLE----TSASYCPAERVANNRGDFRWPRTL 456
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 112,485,115
Number of Sequences: 237096
Number of extensions: 2494527
Number of successful extensions: 6336
Number of sequences better than 10.0: 185
Number of HSP's better than 10.0 without gapping: 5858
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 6187
length of database: 76,859,062
effective HSP length: 89
effective length of database: 55,757,518
effective search space used: 10928473528
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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