Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BmNP06_FL5_P23
(900 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
AJ306454-1|CAC34819.1| 497|Homo sapiens neuronal nicotinic acet... 74 6e-13
Y08416-1|CAA69693.1| 498|Homo sapiens nicotinic acetylcholine r... 72 2e-12
U62439-1|AAB40117.1| 498|Homo sapiens nicotinic acetylcholine r... 72 2e-12
U48861-1|AAA92123.1| 498|Homo sapiens beta 4 nicotinic acetylch... 72 2e-12
BC096082-1|AAH96082.1| 498|Homo sapiens cholinergic receptor, n... 72 2e-12
BC096080-1|AAH96080.1| 498|Homo sapiens cholinergic receptor, n... 72 2e-12
AF306329-1|AAL02062.1| 498|Homo sapiens neuronal nicotinic acet... 72 2e-12
Y08419-1|CAA69696.1| 468|Homo sapiens nicotinic acetylcholine r... 69 3e-11
Y08417-1|CAA69694.1| 458|Homo sapiens nicotinic acetylcholine r... 69 3e-11
X67513-1|CAA47851.1| 423|Homo sapiens nicotinic acetylcholine ... 69 3e-11
U62438-1|AAB40116.1| 458|Homo sapiens nicotinic acetylcholine r... 69 3e-11
U62434-1|AAB40112.1| 468|Homo sapiens nicotinic acetylcholine r... 69 3e-11
BC069788-1|AAH69788.1| 458|Homo sapiens cholinergic receptor, n... 69 3e-11
BC069703-1|AAH69703.1| 458|Homo sapiens cholinergic receptor, n... 69 3e-11
BC069681-1|AAH69681.1| 458|Homo sapiens cholinergic receptor, n... 69 3e-11
BC033639-1|AAH33639.1| 468|Homo sapiens cholinergic receptor, n... 69 3e-11
AJ306481-1|CAC34820.1| 468|Homo sapiens neuronal nicotinic acet... 69 3e-11
AF140765-1|AAD33063.1| 458|Homo sapiens neuronal acetylcholine ... 69 3e-11
X68275-1|CAA48336.1| 451|Homo sapiens nicotinic receptor beta 4... 68 4e-11
M83712-1|AAA58357.1| 468|Homo sapiens nicotinic receptor alpha ... 67 7e-11
Y16282-1|CAA76155.1| 494|Homo sapiens nicotinic acetylcholine r... 67 9e-11
Y08418-1|CAA69695.1| 503|Homo sapiens nicotinic acetylcholine r... 67 9e-11
X53559-1|CAA37625.1| 474|Homo sapiens neuronal nicotinic acetyl... 67 9e-11
U62435-1|AAB40113.1| 494|Homo sapiens nicotinic acetylcholine r... 67 9e-11
U62432-1|AAB40110.1| 504|Homo sapiens nicotinic acetylcholine r... 67 9e-11
M37981-1|AAA59942.1| 503|Homo sapiens neuronal nicotinic acetyl... 67 9e-11
BT006897-1|AAP35543.1| 505|Homo sapiens cholinergic receptor, n... 67 9e-11
BT006646-1|AAP35292.1| 489|Homo sapiens cholinergic receptor, n... 67 9e-11
BC098443-1|AAH98443.1| 504|Homo sapiens cholinergic receptor, n... 67 9e-11
BC014456-1|AAH14456.1| 494|Homo sapiens cholinergic receptor, n... 67 9e-11
BC006114-1|AAH06114.1| 489|Homo sapiens CHRNA3 protein protein. 67 9e-11
BC002996-1|AAH02996.1| 505|Homo sapiens cholinergic receptor, n... 67 9e-11
BC001642-1|AAH01642.1| 505|Homo sapiens cholinergic receptor, n... 67 9e-11
BC000513-1|AAH00513.1| 505|Homo sapiens cholinergic receptor, n... 67 9e-11
AJ007783-1|CAA07682.1| 504|Homo sapiens nicotinic acetylcholine... 67 9e-11
AF385584-1|AAK68110.1| 489|Homo sapiens nicotinic cholinergic r... 67 9e-11
AB079251-1|BAC06855.1| 494|Homo sapiens Nicotinic acetylcholine... 67 9e-11
Y16281-1|CAA76154.1| 529|Homo sapiens nicotinic acetylcholine r... 65 3e-10
X14830-1|CAA32939.1| 501|Homo sapiens protein ( Human mRNA for ... 65 3e-10
U62431-1|AAB40109.1| 529|Homo sapiens nicotinic acetylcholine r... 65 3e-10
BC011371-1|AAH11371.1| 501|Homo sapiens cholinergic receptor, n... 65 3e-10
M86383-1|AAC84176.1| 502|Homo sapiens nicotinic acetylcholine r... 64 5e-10
Y08421-1|CAA69698.1| 627|Homo sapiens nicotinic acetylcholine r... 64 7e-10
X89741-1|CAA61893.1| 627|Homo sapiens neuronal acetylcholine re... 64 7e-10
X87629-1|CAA60959.1| 602|Homo sapiens nicotinic acetylcholine r... 64 7e-10
U62433-1|AAB40111.1| 627|Homo sapiens nicotinic acetylcholine r... 64 7e-10
L35901-1|AAA64743.1| 627|Homo sapiens nicotinic acetylcholine r... 64 7e-10
DQ093071-1|AAY88737.1| 627|Homo sapiens cholinergic receptor, n... 64 7e-10
BC096290-1|AAH96290.1| 627|Homo sapiens cholinergic receptor, n... 64 7e-10
BC023553-1|AAH23553.1| 501|Homo sapiens cholinergic receptor, n... 64 7e-10
X66403-1|CAA47030.1| 493|Homo sapiens acetylcholine receptor ep... 64 9e-10
AF105999-1|AAD24503.1| 493|Homo sapiens acetylcholine receptor ... 64 9e-10
X01715-1|CAA25861.1| 520|Homo sapiens acetylcholine receptor ga... 61 5e-09
AC092165-3|AAY24103.1| 520|Homo sapiens unknown protein. 61 5e-09
BC113575-1|AAI13576.1| 479|Homo sapiens cholinergic receptor, n... 60 1e-08
BC113549-1|AAI13550.1| 479|Homo sapiens cholinergic receptor, n... 60 1e-08
AY123244-1|AAM74523.1| 479|Homo sapiens nicotinic acetylcholine... 60 1e-08
AJ243342-1|CAB65091.1| 479|Homo sapiens nicotinic acetylcholine... 60 1e-08
AF227732-1|AAF61920.1| 470|Homo sapiens nicotinic acetylcholine... 60 1e-08
AC118275-1|AAY40986.1| 479|Homo sapiens unknown protein. 60 1e-08
Y08415-1|CAA69692.1| 502|Homo sapiens nicotinic acetylcholine r... 59 2e-08
X53179-1|CAA37320.1| 502|Homo sapiens precursor peptide (AA -25... 59 2e-08
U62437-1|AAB40115.1| 502|Homo sapiens nicotinic acetylcholine r... 59 2e-08
BC075041-1|AAH75041.1| 502|Homo sapiens cholinergic receptor, n... 59 2e-08
BC075040-1|AAH75040.1| 502|Homo sapiens cholinergic receptor, n... 59 2e-08
AL592078-3|CAI16184.1| 502|Homo sapiens cholinergic receptor, n... 59 2e-08
AJ295237-1|CAC16144.1| 450|Homo sapiens neuronal nicotinic acet... 59 2e-08
AJ278118-1|CAC20435.1| 450|Homo sapiens neuronal nicotinic acet... 59 2e-08
AJ001935-1|CAA05108.1| 504|Homo sapiens CHRNB2 protein. 59 2e-08
AF327367-1|AAK14333.1| 450|Homo sapiens nicotinic acetylcholine... 59 2e-08
AF199235-1|AAG00795.2| 450|Homo sapiens nicotinic acetylcholine... 59 2e-08
AF077186-1|AAD45422.1| 502|Homo sapiens neuronal nicotinic acet... 59 2e-08
DQ644022-1|ABG35128.1| 456|Homo sapiens 5-HT3 receptor subunit ... 58 6e-08
BC131799-1|AAI31800.1| 447|Homo sapiens 5-hydroxytryptamine (se... 58 6e-08
BC101185-1|AAI01186.1| 374|Homo sapiens HTR3E protein protein. 58 6e-08
BC101183-1|AAI01184.1| 471|Homo sapiens 5-hydroxytryptamine (se... 58 6e-08
BC101182-1|AAI01183.1| 471|Homo sapiens 5-hydroxytryptamine (se... 58 6e-08
AY159813-1|AAO38167.2| 471|Homo sapiens 5-hydroxytryptamine ser... 58 6e-08
AF459285-1|AAL66182.1| 447|Homo sapiens 5-hydroxytryptamine rec... 57 8e-08
X55019-1|CAA38759.1| 517|Homo sapiens acetylcholine receptor de... 57 1e-07
BC093925-1|AAH93925.1| 517|Homo sapiens cholinergic receptor, n... 57 1e-07
BC093923-1|AAH93923.1| 517|Homo sapiens cholinergic receptor, n... 57 1e-07
AC092165-2|AAY24102.1| 517|Homo sapiens unknown protein. 57 1e-07
Y00762-1|CAA68731.1| 457|Homo sapiens protein ( Human mRNA for ... 56 2e-07
X02502-1|CAA26344.1| 457|Homo sapiens acetylcholine receptor pr... 56 2e-07
S77094-1|AAD14247.1| 457|Homo sapiens nicotinic acetylcholine r... 56 2e-07
BC006314-1|AAH06314.1| 269|Homo sapiens CHRNA1 protein protein. 56 2e-07
AC018890-1|AAY14687.1| 457|Homo sapiens unknown protein. 56 2e-07
AY349353-1|AAQ93477.1| 456|Homo sapiens 5-HT3c1 serotonin recep... 56 2e-07
AY349352-1|AAQ93476.1| 441|Homo sapiens 5-HT3c1 serotonin recep... 56 2e-07
BC110597-1|AAI10598.1| 411|Homo sapiens ligand-gated ion channe... 53 2e-06
AF512521-1|AAO20969.1| 411|Homo sapiens ligand-gated ion channe... 53 2e-06
L08485-1|AAA58490.1| 462|Homo sapiens GABA-benzodiazepine recep... 52 2e-06
BT009830-1|AAP88832.1| 462|Homo sapiens gamma-aminobutyric acid... 52 2e-06
BC113422-1|AAI13423.1| 462|Homo sapiens gamma-aminobutyric acid... 52 2e-06
BC111979-1|AAI11980.1| 462|Homo sapiens gamma-aminobutyric acid... 52 2e-06
AB223030-1|BAE19924.1| 411|Homo sapiens ligand-gated ion-channe... 52 2e-06
Z23141-1|CAA80672.1| 479|Homo sapiens cholinergic receptor, nic... 52 4e-06
Y08420-1|CAA69697.1| 502|Homo sapiens nicotinic acetylcholine r... 52 4e-06
X70297-1|CAA49778.1| 502|Homo sapiens neuronal nicotinic acetyl... 52 4e-06
U62436-1|AAB40114.1| 502|Homo sapiens nicotinic acetylcholine r... 52 4e-06
M59216-1|AAA35862.1| 474|Homo sapiens gamma-aminobutyric acid r... 52 4e-06
AJ586911-1|CAE52911.1| 502|Homo sapiens nicotinic acetylcholine... 52 4e-06
S77554-1|AAB33983.1| 474|Homo sapiens GABAA receptor beta 2 sub... 51 5e-06
S77553-1|AAB33982.1| 512|Homo sapiens GABAA receptor beta 2 sub... 51 5e-06
S67368-1|AAB29370.1| 474|Homo sapiens gamma-aminobutyric acid A... 51 5e-06
BC105639-1|AAI05640.1| 474|Homo sapiens GABRB2 protein protein. 51 5e-06
BC099719-1|AAH99719.1| 474|Homo sapiens GABRB2 protein protein. 51 5e-06
BC099705-1|AAH99705.1| 474|Homo sapiens GABRB2 protein protein. 51 5e-06
X14767-1|CAA32875.1| 474|Homo sapiens GABA-A receptor beta 1 su... 51 7e-06
U40583-1|AAA83561.1| 502|Homo sapiens alpha 7 neuronal nicotini... 50 9e-06
AF385585-1|AAK68111.1| 502|Homo sapiens nicotinic cholinergic r... 50 9e-06
BC111802-1|AAI11803.1| 465|Homo sapiens CHRNG protein protein. 50 2e-05
BC028629-1|AAH28629.1| 492|Homo sapiens gamma-aminobutyric acid... 50 2e-05
S62908-1|AAB27279.1| 492|Homo sapiens gamma-aminobutyric acidA ... 49 2e-05
AK122638-1|BAC85499.1| 266|Homo sapiens yte protein of 76kDa) (... 49 2e-05
AF166361-1|AAG12455.1| 492|Homo sapiens GABA receptor subunit a... 49 2e-05
U30461-1|AAB52519.1| 554|Homo sapiens GABAA receptor subunit al... 47 1e-04
BC035055-1|AAH35055.1| 554|Homo sapiens gamma-aminobutyric acid... 47 1e-04
U77731-2|AAB38273.1| 360|Homo sapiens glycine receptor alpha 2B... 46 1e-04
CR450343-1|CAG29339.1| 452|Homo sapiens GLRA2 protein. 46 1e-04
BC096083-1|AAH96083.1| 198|Homo sapiens CHRNB4 protein protein. 46 1e-04
BC096081-1|AAH96081.1| 198|Homo sapiens CHRNB4 protein protein. 46 1e-04
BC022449-1|AAH22449.1| 474|Homo sapiens gamma-aminobutyric acid... 46 1e-04
AY437084-1|AAR87843.1| 452|Homo sapiens glycine receptor alpha2... 46 1e-04
AJ003080-1|CAA05853.1| 238|Homo sapiens serotonin receptor prot... 46 1e-04
X52008-1|CAA36257.1| 452|Homo sapiens inhibitory glycine recept... 46 2e-04
U77731-1|AAB38272.1| 360|Homo sapiens glycine receptor alpha 2 ... 46 2e-04
BC032864-1|AAH32864.1| 452|Homo sapiens glycine receptor, alpha... 46 2e-04
AY437083-1|AAR87842.1| 452|Homo sapiens glycine receptor alpha2... 46 2e-04
AF053495-1|AAC35290.1| 452|Homo sapiens glycine receptor alpha ... 46 2e-04
U95367-1|AAC51357.1| 440|Homo sapiens GABA-A receptor pi subuni... 46 2e-04
BC109211-1|AAI09212.1| 632|Homo sapiens gamma-aminobutyric acid... 46 2e-04
BC109210-1|AAI09211.1| 632|Homo sapiens gamma-aminobutyric acid... 46 2e-04
BC109106-1|AAI09107.1| 440|Homo sapiens gamma-aminobutyric acid... 46 2e-04
BC109105-1|AAI09106.1| 440|Homo sapiens gamma-aminobutyric acid... 46 2e-04
BC074865-1|AAH74865.1| 440|Homo sapiens gamma-aminobutyric acid... 46 2e-04
BC074810-1|AAH74810.1| 440|Homo sapiens gamma-aminobutyric acid... 46 2e-04
BC033801-1|AAH33801.1| 452|Homo sapiens gamma-aminobutyric acid... 46 2e-04
AL391845-4|CAI15436.1| 452|Homo sapiens gamma-aminobutyric acid... 46 2e-04
AF189259-1|AAF70380.1| 632|Homo sapiens GABA-A receptor theta s... 46 2e-04
AF144648-1|AAD51172.1| 627|Homo sapiens GABA-A receptor theta p... 46 2e-04
AF016917-1|AAB70007.1| 452|Homo sapiens GABA-A receptor delta s... 46 2e-04
AF009702-1|AAC24194.1| 440|Homo sapiens GABA-A receptor pi subu... 46 2e-04
S81944-1|AAB36480.1| 453|Homo sapiens gamma-aminobutyric acid t... 45 3e-04
BC099641-1|AAH99641.1| 453|Homo sapiens gamma-aminobutyric acid... 45 3e-04
BC099640-1|AAH99640.1| 453|Homo sapiens gamma-aminobutyric acid... 45 3e-04
BC096242-1|AAH96242.1| 453|Homo sapiens gamma-aminobutyric acid... 45 3e-04
BC096241-1|AAH96241.1| 453|Homo sapiens gamma-aminobutyric acid... 45 3e-04
X52009-1|CAA36258.1| 449|Homo sapiens inhibitory glycine recept... 41 0.005
BC114947-1|AAI14948.1| 457|Homo sapiens GLRA1 protein protein. 41 0.005
BC074980-1|AAH74980.1| 449|Homo sapiens glycine receptor, alpha... 41 0.005
Z93848-1|CAI41994.1| 376|Homo sapiens glycine receptor, alpha 4... 40 0.012
U93917-1|AAC39917.1| 449|Homo sapiens glycine receptor alpha 3 ... 40 0.012
BC036086-1|AAH36086.1| 464|Homo sapiens glycine receptor, alpha... 40 0.012
AL049610-1|CAI42158.1| 376|Homo sapiens glycine receptor, alpha... 40 0.012
AF017724-1|AAC39919.1| 465|Homo sapiens glycine receptor alpha ... 40 0.012
AB209359-1|BAD92596.1| 533|Homo sapiens cholinergic receptor, n... 39 0.021
BC114967-1|AAI14968.1| 366|Homo sapiens GLRA1 protein protein. 39 0.028
BC096291-1|AAH96291.1| 556|Homo sapiens CHRNA4 protein protein. 38 0.038
BC146774-1|AAI46775.1| 1114|Homo sapiens GPR124 protein protein. 31 7.5
AY181242-1|AAO27354.1| 1331|Homo sapiens G protein-coupled recep... 31 7.5
AK074099-1|BAB84925.1| 1310|Homo sapiens FLJ00170 protein protein. 31 7.5
AF378755-1|AAL11992.1| 1331|Homo sapiens tumor endothelial marke... 31 7.5
AB040964-1|BAA96055.2| 1206|Homo sapiens KIAA1531 protein protein. 31 7.5
>AJ306454-1|CAC34819.1| 497|Homo sapiens neuronal nicotinic
acetylcholine receptor beta-4 subunit protein.
Length = 497
Score = 74.1 bits (174), Expect = 6e-13
Identities = 47/171 (27%), Positives = 80/171 (46%), Gaps = 8/171 (4%)
Frame = +1
Query: 58 AIASAAECENATSLSLMIDSLL--ATYDRESPP--DSKIVVNLTLHLRHA---NIRESES 216
A+ C A + ++D LL Y+ P S ++++ L L A ++ E E
Sbjct: 14 ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQ 73
Query: 217 TVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRAR 393
+ L+ W D RL+WN+ + G + + ++R+W PD+VL N T
Sbjct: 74 IMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNDGTYEVSVYTNLI 133
Query: 394 VSNNGSVSWIKRLDISTPISMQLDIWPNDMQTCTFKFGSRMHNSDEMDFVI 546
V +NGSV W+ + +++ +P D Q CT KF S ++ E+D V+
Sbjct: 134 VRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRSWTYDHTEIDMVL 184
>Y08416-1|CAA69693.1| 498|Homo sapiens nicotinic acetylcholine
receptor beta4 subunit precursor protein.
Length = 498
Score = 72.1 bits (169), Expect = 2e-12
Identities = 48/172 (27%), Positives = 81/172 (47%), Gaps = 9/172 (5%)
Frame = +1
Query: 58 AIASAAECENATSLSLMIDSLL--ATYDRESPP--DSKIVVNLTLHLRHA---NIRESES 216
A+ C A + ++D LL Y+ P S ++++ L L A ++ E E
Sbjct: 14 ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQ 73
Query: 217 TVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRA 390
+ L+ W D RL+WN+ + G + + ++R+W PD+VL N A T
Sbjct: 74 IMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNADGTYEVSVYTNL 133
Query: 391 RVSNNGSVSWIKRLDISTPISMQLDIWPNDMQTCTFKFGSRMHNSDEMDFVI 546
V +NGSV W+ + +++ +P D Q CT KF S ++ E+D V+
Sbjct: 134 IVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRSWTYDHTEIDMVL 185
>U62439-1|AAB40117.1| 498|Homo sapiens nicotinic acetylcholine
receptor beta4 subunit precursor protein.
Length = 498
Score = 72.1 bits (169), Expect = 2e-12
Identities = 48/172 (27%), Positives = 81/172 (47%), Gaps = 9/172 (5%)
Frame = +1
Query: 58 AIASAAECENATSLSLMIDSLL--ATYDRESPP--DSKIVVNLTLHLRHA---NIRESES 216
A+ C A + ++D LL Y+ P S ++++ L L A ++ E E
Sbjct: 14 ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQ 73
Query: 217 TVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRA 390
+ L+ W D RL+WN+ + G + + ++R+W PD+VL N A T
Sbjct: 74 IMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNADGTYEVSVYTNL 133
Query: 391 RVSNNGSVSWIKRLDISTPISMQLDIWPNDMQTCTFKFGSRMHNSDEMDFVI 546
V +NGSV W+ + +++ +P D Q CT KF S ++ E+D V+
Sbjct: 134 IVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRSWTYDHTEIDMVL 185
>U48861-1|AAA92123.1| 498|Homo sapiens beta 4 nicotinic
acetylcholine receptor subunit protein.
Length = 498
Score = 72.1 bits (169), Expect = 2e-12
Identities = 48/172 (27%), Positives = 81/172 (47%), Gaps = 9/172 (5%)
Frame = +1
Query: 58 AIASAAECENATSLSLMIDSLL--ATYDRESPP--DSKIVVNLTLHLRHA---NIRESES 216
A+ C A + ++D LL Y+ P S ++++ L L A ++ E E
Sbjct: 14 ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQ 73
Query: 217 TVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRA 390
+ L+ W D RL+WN+ + G + + ++R+W PD+VL N A T
Sbjct: 74 IMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNADGTYEVSVYTNL 133
Query: 391 RVSNNGSVSWIKRLDISTPISMQLDIWPNDMQTCTFKFGSRMHNSDEMDFVI 546
V +NGSV W+ + +++ +P D Q CT KF S ++ E+D V+
Sbjct: 134 IVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRSWTYDHTEIDMVL 185
>BC096082-1|AAH96082.1| 498|Homo sapiens cholinergic receptor,
nicotinic, beta 4 protein.
Length = 498
Score = 72.1 bits (169), Expect = 2e-12
Identities = 48/172 (27%), Positives = 81/172 (47%), Gaps = 9/172 (5%)
Frame = +1
Query: 58 AIASAAECENATSLSLMIDSLL--ATYDRESPP--DSKIVVNLTLHLRHA---NIRESES 216
A+ C A + ++D LL Y+ P S ++++ L L A ++ E E
Sbjct: 14 ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQ 73
Query: 217 TVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRA 390
+ L+ W D RL+WN+ + G + + ++R+W PD+VL N A T
Sbjct: 74 IMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNADGTYEVSVYTNL 133
Query: 391 RVSNNGSVSWIKRLDISTPISMQLDIWPNDMQTCTFKFGSRMHNSDEMDFVI 546
V +NGSV W+ + +++ +P D Q CT KF S ++ E+D V+
Sbjct: 134 IVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRSWTYDHTEIDMVL 185
>BC096080-1|AAH96080.1| 498|Homo sapiens cholinergic receptor,
nicotinic, beta 4 protein.
Length = 498
Score = 72.1 bits (169), Expect = 2e-12
Identities = 48/172 (27%), Positives = 81/172 (47%), Gaps = 9/172 (5%)
Frame = +1
Query: 58 AIASAAECENATSLSLMIDSLL--ATYDRESPP--DSKIVVNLTLHLRHA---NIRESES 216
A+ C A + ++D LL Y+ P S ++++ L L A ++ E E
Sbjct: 14 ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQ 73
Query: 217 TVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRA 390
+ L+ W D RL+WN+ + G + + ++R+W PD+VL N A T
Sbjct: 74 IMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNADGTYEVSVYTNL 133
Query: 391 RVSNNGSVSWIKRLDISTPISMQLDIWPNDMQTCTFKFGSRMHNSDEMDFVI 546
V +NGSV W+ + +++ +P D Q CT KF S ++ E+D V+
Sbjct: 134 IVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRSWTYDHTEIDMVL 185
>AF306329-1|AAL02062.1| 498|Homo sapiens neuronal nicotinic
acetylcholine receptor beta 4 subunit protein.
Length = 498
Score = 72.1 bits (169), Expect = 2e-12
Identities = 48/172 (27%), Positives = 81/172 (47%), Gaps = 9/172 (5%)
Frame = +1
Query: 58 AIASAAECENATSLSLMIDSLL--ATYDRESPP--DSKIVVNLTLHLRHA---NIRESES 216
A+ C A + ++D LL Y+ P S ++++ L L A ++ E E
Sbjct: 14 ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQ 73
Query: 217 TVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRA 390
+ L+ W D RL+WN+ + G + + ++R+W PD+VL N A T
Sbjct: 74 IMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNADGTYEVSVYTNL 133
Query: 391 RVSNNGSVSWIKRLDISTPISMQLDIWPNDMQTCTFKFGSRMHNSDEMDFVI 546
V +NGSV W+ + +++ +P D Q CT KF S ++ E+D V+
Sbjct: 134 IVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRSWTYDHTEIDMVL 185
>Y08419-1|CAA69696.1| 468|Homo sapiens nicotinic acetylcholine
receptor alpha5 subunit precursor protein.
Length = 468
Score = 68.5 bits (160), Expect = 3e-11
Identities = 37/154 (24%), Positives = 74/154 (48%), Gaps = 6/154 (3%)
Frame = +1
Query: 106 MIDSLLATYDRESPP----DSKIVVNLTLHLRH-ANIRESESTVRILADLQMNWIDKRLS 270
++ L Y+R P + KI + L + ++ E + L+ WID +L
Sbjct: 50 LLKDLFQDYERWVRPVEHLNDKIKIKFGLAISQLVDVDEKNQLMTTNVWLKQEWIDVKLR 109
Query: 271 WNAGEWG-CSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVSWIKRLDISTP 447
WN ++G V S+ +W PD+VL + A + + + NG+V+W + +
Sbjct: 110 WNPDDYGGIKVIRVPSDSVWTPDIVLFDNADGRFEGTSTKTVIRYNGTVTWTPPANYKSS 169
Query: 448 ISMQLDIWPNDMQTCTFKFGSRMHNSDEMDFVID 549
++ + +P D+Q C+ KFGS ++ ++D +++
Sbjct: 170 CTIDVTFFPFDLQNCSMKFGSWTYDGSQVDIILE 203
>Y08417-1|CAA69694.1| 458|Homo sapiens nicotinic acetylcholine
receptor beta3 subunit precursor protein.
Length = 458
Score = 68.5 bits (160), Expect = 3e-11
Identities = 34/105 (32%), Positives = 53/105 (50%), Gaps = 2/105 (1%)
Frame = +1
Query: 238 LQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLL-NAAATTAGDYALRARVSNNGS 411
L+ W D +L WN ++G + V SE LW PD+VL NA G + V +NG+
Sbjct: 81 LKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFEGSLMTKVIVKSNGT 140
Query: 412 VSWIKRLDISTPISMQLDIWPNDMQTCTFKFGSRMHNSDEMDFVI 546
V W + +M + +P D Q C+ KFGS ++ +D ++
Sbjct: 141 VVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGTMVDLIL 185
>X67513-1|CAA47851.1| 423|Homo sapiens nicotinic acetylcholine
receptor beta-3 subunit protein.
Length = 423
Score = 68.5 bits (160), Expect = 3e-11
Identities = 34/105 (32%), Positives = 53/105 (50%), Gaps = 2/105 (1%)
Frame = +1
Query: 238 LQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLL-NAAATTAGDYALRARVSNNGS 411
L+ W D +L WN ++G + V SE LW PD+VL NA G + V +NG+
Sbjct: 46 LKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFEGSLMTKVIVKSNGT 105
Query: 412 VSWIKRLDISTPISMQLDIWPNDMQTCTFKFGSRMHNSDEMDFVI 546
V W + +M + +P D Q C+ KFGS ++ +D ++
Sbjct: 106 VVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGTMVDLIL 150
>U62438-1|AAB40116.1| 458|Homo sapiens nicotinic acetylcholine
receptor beta3 subunit precursor protein.
Length = 458
Score = 68.5 bits (160), Expect = 3e-11
Identities = 34/105 (32%), Positives = 53/105 (50%), Gaps = 2/105 (1%)
Frame = +1
Query: 238 LQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLL-NAAATTAGDYALRARVSNNGS 411
L+ W D +L WN ++G + V SE LW PD+VL NA G + V +NG+
Sbjct: 81 LKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFEGSLMTKVIVKSNGT 140
Query: 412 VSWIKRLDISTPISMQLDIWPNDMQTCTFKFGSRMHNSDEMDFVI 546
V W + +M + +P D Q C+ KFGS ++ +D ++
Sbjct: 141 VVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGTMVDLIL 185
>U62434-1|AAB40112.1| 468|Homo sapiens nicotinic acetylcholine
receptor alpha5 subunit precursor protein.
Length = 468
Score = 68.5 bits (160), Expect = 3e-11
Identities = 37/154 (24%), Positives = 74/154 (48%), Gaps = 6/154 (3%)
Frame = +1
Query: 106 MIDSLLATYDRESPP----DSKIVVNLTLHLRH-ANIRESESTVRILADLQMNWIDKRLS 270
++ L Y+R P + KI + L + ++ E + L+ WID +L
Sbjct: 50 LLKDLFQDYERWVRPVEHLNDKIKIKFGLAISQLVDVDEKNQLMTTNVWLKQEWIDVKLR 109
Query: 271 WNAGEWG-CSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVSWIKRLDISTP 447
WN ++G V S+ +W PD+VL + A + + + NG+V+W + +
Sbjct: 110 WNPDDYGGIKVIRVPSDSVWTPDIVLFDNADGRFEGTSTKTVIRYNGTVTWTPPANYKSS 169
Query: 448 ISMQLDIWPNDMQTCTFKFGSRMHNSDEMDFVID 549
++ + +P D+Q C+ KFGS ++ ++D +++
Sbjct: 170 CTIDVTFFPFDLQNCSMKFGSWTYDGSQVDIILE 203
>BC069788-1|AAH69788.1| 458|Homo sapiens cholinergic receptor,
nicotinic, beta 3 protein.
Length = 458
Score = 68.5 bits (160), Expect = 3e-11
Identities = 34/105 (32%), Positives = 53/105 (50%), Gaps = 2/105 (1%)
Frame = +1
Query: 238 LQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLL-NAAATTAGDYALRARVSNNGS 411
L+ W D +L WN ++G + V SE LW PD+VL NA G + V +NG+
Sbjct: 81 LKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFEGSLMTKVIVKSNGT 140
Query: 412 VSWIKRLDISTPISMQLDIWPNDMQTCTFKFGSRMHNSDEMDFVI 546
V W + +M + +P D Q C+ KFGS ++ +D ++
Sbjct: 141 VVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGTMVDLIL 185
>BC069703-1|AAH69703.1| 458|Homo sapiens cholinergic receptor,
nicotinic, beta 3 protein.
Length = 458
Score = 68.5 bits (160), Expect = 3e-11
Identities = 34/105 (32%), Positives = 53/105 (50%), Gaps = 2/105 (1%)
Frame = +1
Query: 238 LQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLL-NAAATTAGDYALRARVSNNGS 411
L+ W D +L WN ++G + V SE LW PD+VL NA G + V +NG+
Sbjct: 81 LKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFEGSLMTKVIVKSNGT 140
Query: 412 VSWIKRLDISTPISMQLDIWPNDMQTCTFKFGSRMHNSDEMDFVI 546
V W + +M + +P D Q C+ KFGS ++ +D ++
Sbjct: 141 VVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGTMVDLIL 185
>BC069681-1|AAH69681.1| 458|Homo sapiens cholinergic receptor,
nicotinic, beta 3 protein.
Length = 458
Score = 68.5 bits (160), Expect = 3e-11
Identities = 34/105 (32%), Positives = 53/105 (50%), Gaps = 2/105 (1%)
Frame = +1
Query: 238 LQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLL-NAAATTAGDYALRARVSNNGS 411
L+ W D +L WN ++G + V SE LW PD+VL NA G + V +NG+
Sbjct: 81 LKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFEGSLMTKVIVKSNGT 140
Query: 412 VSWIKRLDISTPISMQLDIWPNDMQTCTFKFGSRMHNSDEMDFVI 546
V W + +M + +P D Q C+ KFGS ++ +D ++
Sbjct: 141 VVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGTMVDLIL 185
>BC033639-1|AAH33639.1| 468|Homo sapiens cholinergic receptor,
nicotinic, alpha 5 protein.
Length = 468
Score = 68.5 bits (160), Expect = 3e-11
Identities = 37/154 (24%), Positives = 74/154 (48%), Gaps = 6/154 (3%)
Frame = +1
Query: 106 MIDSLLATYDRESPP----DSKIVVNLTLHLRH-ANIRESESTVRILADLQMNWIDKRLS 270
++ L Y+R P + KI + L + ++ E + L+ WID +L
Sbjct: 50 LLKDLFQDYERWVRPVEHLNDKIKIKFGLAISQLVDVDEKNQLMTTNVWLKQEWIDVKLR 109
Query: 271 WNAGEWG-CSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVSWIKRLDISTP 447
WN ++G V S+ +W PD+VL + A + + + NG+V+W + +
Sbjct: 110 WNPDDYGGIKVIRVPSDSVWTPDIVLFDNADGRFEGTSTKTVIRYNGTVTWTPPANYKSS 169
Query: 448 ISMQLDIWPNDMQTCTFKFGSRMHNSDEMDFVID 549
++ + +P D+Q C+ KFGS ++ ++D +++
Sbjct: 170 CTIDVTFFPFDLQNCSMKFGSWTYDGSQVDIILE 203
>AJ306481-1|CAC34820.1| 468|Homo sapiens neuronal nicotinic
acetylcholine receptor alpha-5subunit protein.
Length = 468
Score = 68.5 bits (160), Expect = 3e-11
Identities = 37/154 (24%), Positives = 74/154 (48%), Gaps = 6/154 (3%)
Frame = +1
Query: 106 MIDSLLATYDRESPP----DSKIVVNLTLHLRH-ANIRESESTVRILADLQMNWIDKRLS 270
++ L Y+R P + KI + L + ++ E + L+ WID +L
Sbjct: 50 LLKDLFQDYERWVRPVEHLNDKIKIKFGLAISQLVDVDEKNQLMTTNVWLKQEWIDVKLR 109
Query: 271 WNAGEWG-CSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVSWIKRLDISTP 447
WN ++G V S+ +W PD+VL + A + + + NG+V+W + +
Sbjct: 110 WNPDDYGGIKVIRVPSDSVWTPDIVLFDNADGRFEGTSTKTVIRYNGTVTWTPPANYKSS 169
Query: 448 ISMQLDIWPNDMQTCTFKFGSRMHNSDEMDFVID 549
++ + +P D+Q C+ KFGS ++ ++D +++
Sbjct: 170 CTIDVTFFPFDLQNCSMKFGSWTYDGSQVDIILE 203
>AF140765-1|AAD33063.1| 458|Homo sapiens neuronal acetylcholine
receptor beta-3 subunit precursor protein.
Length = 458
Score = 68.5 bits (160), Expect = 3e-11
Identities = 34/105 (32%), Positives = 53/105 (50%), Gaps = 2/105 (1%)
Frame = +1
Query: 238 LQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLL-NAAATTAGDYALRARVSNNGS 411
L+ W D +L WN ++G + V SE LW PD+VL NA G + V +NG+
Sbjct: 81 LKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFEGSLMTKVIVKSNGT 140
Query: 412 VSWIKRLDISTPISMQLDIWPNDMQTCTFKFGSRMHNSDEMDFVI 546
V W + +M + +P D Q C+ KFGS ++ +D ++
Sbjct: 141 VVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGTMVDLIL 185
>X68275-1|CAA48336.1| 451|Homo sapiens nicotinic receptor beta 4
subunit protein.
Length = 451
Score = 68.1 bits (159), Expect = 4e-11
Identities = 39/132 (29%), Positives = 65/132 (49%), Gaps = 3/132 (2%)
Frame = +1
Query: 160 IVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 333
I + L L L ++ E + + L+ W D RL+WN+ + G + + ++R+W P
Sbjct: 7 ISIKLQLSLAQLISVNERDEIMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLP 66
Query: 334 DVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDIWPNDMQTCTFKFGS 510
D+VL N A T V +NGSV W+ + +++ +P D Q CT KF S
Sbjct: 67 DIVLYNNADGTYEVSVYTNLIVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRS 126
Query: 511 RMHNSDEMDFVI 546
++ E+D V+
Sbjct: 127 WTYDHTEIDMVL 138
>M83712-1|AAA58357.1| 468|Homo sapiens nicotinic receptor alpha 5
subunit protein.
Length = 468
Score = 67.3 bits (157), Expect = 7e-11
Identities = 37/154 (24%), Positives = 73/154 (47%), Gaps = 6/154 (3%)
Frame = +1
Query: 106 MIDSLLATYDRESPP----DSKIVVNLTLHLRH-ANIRESESTVRILADLQMNWIDKRLS 270
++ L Y+R P + KI + L + ++ E + L+ WID +L
Sbjct: 50 LLKDLFQDYERWVRPVEHLNDKIKIKFGLAISQLVDVDEKNQLMTTNVWLKQEWIDVKLR 109
Query: 271 WNAGEWG-CSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVSWIKRLDISTP 447
WN ++G V S+ W PD+VL + A + + + NG+V+W + +
Sbjct: 110 WNPDDYGGIKVIRVPSDSSWTPDIVLFDNADGRFEGTSTKTVIRYNGTVTWTPPANYKSS 169
Query: 448 ISMQLDIWPNDMQTCTFKFGSRMHNSDEMDFVID 549
++ + +P D+Q C+ KFGS ++ ++D +++
Sbjct: 170 CTIDVTFFPFDLQNCSMKFGSWTYDGSQVDIILE 203
>Y16282-1|CAA76155.1| 494|Homo sapiens nicotinic acetylcholine
receptor alpha6 subunit precursor protein.
Length = 494
Score = 66.9 bits (156), Expect = 9e-11
Identities = 43/166 (25%), Positives = 78/166 (46%), Gaps = 10/166 (6%)
Frame = +1
Query: 79 CENATSLSLMIDSLLATYDRESPPDSKIVVNLTLHL-----RHANIRESESTVRILADLQ 243
C + + L + Y++ P + +T+H + AN+ E + L+
Sbjct: 28 CVGCATEERLFHKLFSHYNQFIRPVENVSDPVTVHFEVAITQLANVDEVNQIMETNLWLR 87
Query: 244 MNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNG 408
W D +L W+ E+ G T V ++++W+PD+VL N A GD+ + +A + NG
Sbjct: 88 HIWNDYKLRWDPMEYDGIETLRVPADKIWKPDIVLYNNAV---GDFQVEGKTKALLKYNG 144
Query: 409 SVSWIKRLDISTPISMQLDIWPNDMQTCTFKFGSRMHNSDEMDFVI 546
++W + M + +P D Q C+ KFGS ++ E+D +I
Sbjct: 145 MITWTPPAIFKSSCPMDITFFPFDHQNCSLKFGSWTYDKAEIDLLI 190
>Y08418-1|CAA69695.1| 503|Homo sapiens nicotinic acetylcholine
receptor alpha3 subunit precursor protein.
Length = 503
Score = 66.9 bits (156), Expect = 9e-11
Identities = 32/105 (30%), Positives = 57/105 (54%), Gaps = 2/105 (1%)
Frame = +1
Query: 238 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 411
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 85 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 144
Query: 412 VSWIKRLDISTPISMQLDIWPNDMQTCTFKFGSRMHNSDEMDFVI 546
V+WI + + + +P D Q CT KFGS ++ ++D V+
Sbjct: 145 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVL 189
>X53559-1|CAA37625.1| 474|Homo sapiens neuronal nicotinic
acetylcholine receptor alpha-3merase protein.
Length = 474
Score = 66.9 bits (156), Expect = 9e-11
Identities = 32/105 (30%), Positives = 57/105 (54%), Gaps = 2/105 (1%)
Frame = +1
Query: 238 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 411
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 56 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 115
Query: 412 VSWIKRLDISTPISMQLDIWPNDMQTCTFKFGSRMHNSDEMDFVI 546
V+WI + + + +P D Q CT KFGS ++ ++D V+
Sbjct: 116 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVL 160
>U62435-1|AAB40113.1| 494|Homo sapiens nicotinic acetylcholine
receptor alpha6 subunit precursor protein.
Length = 494
Score = 66.9 bits (156), Expect = 9e-11
Identities = 43/166 (25%), Positives = 78/166 (46%), Gaps = 10/166 (6%)
Frame = +1
Query: 79 CENATSLSLMIDSLLATYDRESPPDSKIVVNLTLHL-----RHANIRESESTVRILADLQ 243
C + + L + Y++ P + +T+H + AN+ E + L+
Sbjct: 28 CVGCATEERLFHKLFSHYNQFIRPVENVSDPVTVHFEVAITQLANVDEVNQIMETNLWLR 87
Query: 244 MNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNG 408
W D +L W+ E+ G T V ++++W+PD+VL N A GD+ + +A + NG
Sbjct: 88 HIWNDYKLRWDPMEYDGIETLRVPADKIWKPDIVLYNNAV---GDFQVEGKTKALLKYNG 144
Query: 409 SVSWIKRLDISTPISMQLDIWPNDMQTCTFKFGSRMHNSDEMDFVI 546
++W + M + +P D Q C+ KFGS ++ E+D +I
Sbjct: 145 MITWTPPAIFKSSCPMDITFFPFDHQNCSLKFGSWTYDKAEIDLLI 190
>U62432-1|AAB40110.1| 504|Homo sapiens nicotinic acetylcholine
receptor alpha3 subunit precursor protein.
Length = 504
Score = 66.9 bits (156), Expect = 9e-11
Identities = 32/105 (30%), Positives = 57/105 (54%), Gaps = 2/105 (1%)
Frame = +1
Query: 238 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 411
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 86 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 145
Query: 412 VSWIKRLDISTPISMQLDIWPNDMQTCTFKFGSRMHNSDEMDFVI 546
V+WI + + + +P D Q CT KFGS ++ ++D V+
Sbjct: 146 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVL 190
>M37981-1|AAA59942.1| 503|Homo sapiens neuronal nicotinic
acetylcholine receptor protein.
Length = 503
Score = 66.9 bits (156), Expect = 9e-11
Identities = 32/105 (30%), Positives = 57/105 (54%), Gaps = 2/105 (1%)
Frame = +1
Query: 238 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 411
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 85 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 144
Query: 412 VSWIKRLDISTPISMQLDIWPNDMQTCTFKFGSRMHNSDEMDFVI 546
V+WI + + + +P D Q CT KFGS ++ ++D V+
Sbjct: 145 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVL 189
>BT006897-1|AAP35543.1| 505|Homo sapiens cholinergic receptor,
nicotinic, alpha polypeptide 3 protein.
Length = 505
Score = 66.9 bits (156), Expect = 9e-11
Identities = 32/105 (30%), Positives = 57/105 (54%), Gaps = 2/105 (1%)
Frame = +1
Query: 238 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 411
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 87 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 146
Query: 412 VSWIKRLDISTPISMQLDIWPNDMQTCTFKFGSRMHNSDEMDFVI 546
V+WI + + + +P D Q CT KFGS ++ ++D V+
Sbjct: 147 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVL 191
>BT006646-1|AAP35292.1| 489|Homo sapiens cholinergic receptor,
nicotinic, alpha polypeptide 3 protein.
Length = 489
Score = 66.9 bits (156), Expect = 9e-11
Identities = 32/105 (30%), Positives = 57/105 (54%), Gaps = 2/105 (1%)
Frame = +1
Query: 238 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 411
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 87 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 146
Query: 412 VSWIKRLDISTPISMQLDIWPNDMQTCTFKFGSRMHNSDEMDFVI 546
V+WI + + + +P D Q CT KFGS ++ ++D V+
Sbjct: 147 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVL 191
>BC098443-1|AAH98443.1| 504|Homo sapiens cholinergic receptor,
nicotinic, alpha 3 protein.
Length = 504
Score = 66.9 bits (156), Expect = 9e-11
Identities = 32/105 (30%), Positives = 57/105 (54%), Gaps = 2/105 (1%)
Frame = +1
Query: 238 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 411
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 86 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 145
Query: 412 VSWIKRLDISTPISMQLDIWPNDMQTCTFKFGSRMHNSDEMDFVI 546
V+WI + + + +P D Q CT KFGS ++ ++D V+
Sbjct: 146 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVL 190
>BC014456-1|AAH14456.1| 494|Homo sapiens cholinergic receptor,
nicotinic, alpha 6 protein.
Length = 494
Score = 66.9 bits (156), Expect = 9e-11
Identities = 43/166 (25%), Positives = 78/166 (46%), Gaps = 10/166 (6%)
Frame = +1
Query: 79 CENATSLSLMIDSLLATYDRESPPDSKIVVNLTLHL-----RHANIRESESTVRILADLQ 243
C + + L + Y++ P + +T+H + AN+ E + L+
Sbjct: 28 CVGCATEERLFHKLFSHYNQFIRPVENVSDPVTVHFEVAITQLANVDEVNQIMETNLWLR 87
Query: 244 MNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNG 408
W D +L W+ E+ G T V ++++W+PD+VL N A GD+ + +A + NG
Sbjct: 88 HIWNDYKLRWDPMEYDGIETLRVPADKIWKPDIVLYNNAV---GDFQVEGKTKALLKYNG 144
Query: 409 SVSWIKRLDISTPISMQLDIWPNDMQTCTFKFGSRMHNSDEMDFVI 546
++W + M + +P D Q C+ KFGS ++ E+D +I
Sbjct: 145 MITWTPPAIFKSSCPMDITFFPFDHQNCSLKFGSWTYDKAEIDLLI 190
>BC006114-1|AAH06114.1| 489|Homo sapiens CHRNA3 protein protein.
Length = 489
Score = 66.9 bits (156), Expect = 9e-11
Identities = 32/105 (30%), Positives = 57/105 (54%), Gaps = 2/105 (1%)
Frame = +1
Query: 238 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 411
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 87 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 146
Query: 412 VSWIKRLDISTPISMQLDIWPNDMQTCTFKFGSRMHNSDEMDFVI 546
V+WI + + + +P D Q CT KFGS ++ ++D V+
Sbjct: 147 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVL 191
>BC002996-1|AAH02996.1| 505|Homo sapiens cholinergic receptor,
nicotinic, alpha 3 protein.
Length = 505
Score = 66.9 bits (156), Expect = 9e-11
Identities = 32/105 (30%), Positives = 57/105 (54%), Gaps = 2/105 (1%)
Frame = +1
Query: 238 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 411
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 87 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 146
Query: 412 VSWIKRLDISTPISMQLDIWPNDMQTCTFKFGSRMHNSDEMDFVI 546
V+WI + + + +P D Q CT KFGS ++ ++D V+
Sbjct: 147 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVL 191
>BC001642-1|AAH01642.1| 505|Homo sapiens cholinergic receptor,
nicotinic, alpha 3 protein.
Length = 505
Score = 66.9 bits (156), Expect = 9e-11
Identities = 32/105 (30%), Positives = 57/105 (54%), Gaps = 2/105 (1%)
Frame = +1
Query: 238 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 411
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 87 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 146
Query: 412 VSWIKRLDISTPISMQLDIWPNDMQTCTFKFGSRMHNSDEMDFVI 546
V+WI + + + +P D Q CT KFGS ++ ++D V+
Sbjct: 147 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVL 191
>BC000513-1|AAH00513.1| 505|Homo sapiens cholinergic receptor,
nicotinic, alpha 3 protein.
Length = 505
Score = 66.9 bits (156), Expect = 9e-11
Identities = 32/105 (30%), Positives = 57/105 (54%), Gaps = 2/105 (1%)
Frame = +1
Query: 238 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 411
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 87 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 146
Query: 412 VSWIKRLDISTPISMQLDIWPNDMQTCTFKFGSRMHNSDEMDFVI 546
V+WI + + + +P D Q CT KFGS ++ ++D V+
Sbjct: 147 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVL 191
>AJ007783-1|CAA07682.1| 504|Homo sapiens nicotinic acetylcholine
receptor alpha-3 subunit protein.
Length = 504
Score = 66.9 bits (156), Expect = 9e-11
Identities = 32/105 (30%), Positives = 57/105 (54%), Gaps = 2/105 (1%)
Frame = +1
Query: 238 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 411
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 86 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 145
Query: 412 VSWIKRLDISTPISMQLDIWPNDMQTCTFKFGSRMHNSDEMDFVI 546
V+WI + + + +P D Q CT KFGS ++ ++D V+
Sbjct: 146 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVL 190
>AF385584-1|AAK68110.1| 489|Homo sapiens nicotinic cholinergic
receptor alpha 3 protein.
Length = 489
Score = 66.9 bits (156), Expect = 9e-11
Identities = 32/105 (30%), Positives = 57/105 (54%), Gaps = 2/105 (1%)
Frame = +1
Query: 238 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 411
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 81 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 140
Query: 412 VSWIKRLDISTPISMQLDIWPNDMQTCTFKFGSRMHNSDEMDFVI 546
V+WI + + + +P D Q CT KFGS ++ ++D V+
Sbjct: 141 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVL 185
>AB079251-1|BAC06855.1| 494|Homo sapiens Nicotinic acetylcholine
receptor alpha 6 protein.
Length = 494
Score = 66.9 bits (156), Expect = 9e-11
Identities = 43/166 (25%), Positives = 78/166 (46%), Gaps = 10/166 (6%)
Frame = +1
Query: 79 CENATSLSLMIDSLLATYDRESPPDSKIVVNLTLHL-----RHANIRESESTVRILADLQ 243
C + + L + Y++ P + +T+H + AN+ E + L+
Sbjct: 28 CVGCATEERLFHKLFSHYNQFIRPVENVSDPVTVHFEVAITQLANVDEVNQIMETNLWLR 87
Query: 244 MNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNG 408
W D +L W+ E+ G T V ++++W+PD+VL N A GD+ + +A + NG
Sbjct: 88 HIWNDYKLRWDPMEYDGIETLRVPADKIWKPDIVLYNNAV---GDFQVEGKTKALLKYNG 144
Query: 409 SVSWIKRLDISTPISMQLDIWPNDMQTCTFKFGSRMHNSDEMDFVI 546
++W + M + +P D Q C+ KFGS ++ E+D +I
Sbjct: 145 MITWTPPAIFKSSCPMDITFFPFDHQNCSLKFGSWTYDKAEIDLLI 190
>Y16281-1|CAA76154.1| 529|Homo sapiens nicotinic acetylcholine
receptor alpha2 subunit precursor protein.
Length = 529
Score = 65.3 bits (152), Expect = 3e-10
Identities = 34/102 (33%), Positives = 54/102 (52%), Gaps = 2/102 (1%)
Frame = +1
Query: 238 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAA-ATTAGDYALRARVSNNGS 411
L+ W D +L WN ++G T L V SE +W PD+VL N A A + +A + + G+
Sbjct: 111 LKQEWSDYKLRWNPADFGNITSLRVPSEMIWIPDIVLYNNADGEFAVTHMTKAHLFSTGT 170
Query: 412 VSWIKRLDISTPISMQLDIWPNDMQTCTFKFGSRMHNSDEMD 537
V W+ + S+ + +P D Q C KFGS ++ ++D
Sbjct: 171 VHWVPPAIYKSSCSIDVTFFPFDQQNCKMKFGSWTYDKAKID 212
>X14830-1|CAA32939.1| 501|Homo sapiens protein ( Human mRNA for
muscle acetylcholine receptor beta-subunit. ).
Length = 501
Score = 65.3 bits (152), Expect = 3e-10
Identities = 47/137 (34%), Positives = 70/137 (51%), Gaps = 4/137 (2%)
Frame = +1
Query: 136 RESPPDSKIVVNLTL-HLRHANIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLV 309
RE ++ V L L L N ++ E + ++ DL+ W D RLSW+ E G + +
Sbjct: 46 REVGDRVRVSVGLILAQLISLNEKDEEMSTKVYLDLE--WTDYRLSWDPAEHDGIDSLRI 103
Query: 310 SSERLWRPDVVLLNAAATTAGDYAL--RARVSNNGSVSWIKRLDISTPISMQLDIWPNDM 483
++E +W PDVVLLN D AL VS++GSV W + S+Q+ +P D
Sbjct: 104 TAESVWLPDVVLLNNNDGNF-DVALDISVVVSSDGSVRWQPPGIYRSSCSIQVTYFPFDW 162
Query: 484 QTCTFKFGSRMHNSDEM 534
Q CT F S ++S E+
Sbjct: 163 QNCTMVFSSYSYDSSEV 179
>U62431-1|AAB40109.1| 529|Homo sapiens nicotinic acetylcholine
receptor alpha2 subunit precursor protein.
Length = 529
Score = 65.3 bits (152), Expect = 3e-10
Identities = 34/102 (33%), Positives = 54/102 (52%), Gaps = 2/102 (1%)
Frame = +1
Query: 238 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAA-ATTAGDYALRARVSNNGS 411
L+ W D +L WN ++G T L V SE +W PD+VL N A A + +A + + G+
Sbjct: 111 LKQEWSDYKLRWNPADFGNITSLRVPSEMIWIPDIVLYNNADGEFAVTHMTKAHLFSTGT 170
Query: 412 VSWIKRLDISTPISMQLDIWPNDMQTCTFKFGSRMHNSDEMD 537
V W+ + S+ + +P D Q C KFGS ++ ++D
Sbjct: 171 VHWVPPAIYKSSCSIDVTFFPFDQQNCKMKFGSWTYDKAKID 212
>BC011371-1|AAH11371.1| 501|Homo sapiens cholinergic receptor,
nicotinic, beta 1 (muscle) protein.
Length = 501
Score = 65.3 bits (152), Expect = 3e-10
Identities = 47/137 (34%), Positives = 70/137 (51%), Gaps = 4/137 (2%)
Frame = +1
Query: 136 RESPPDSKIVVNLTL-HLRHANIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLV 309
RE ++ V L L L N ++ E + ++ DL+ W D RLSW+ E G + +
Sbjct: 46 REVGDRVRVSVGLILAQLISLNEKDEEMSTKVYLDLE--WTDYRLSWDPAEHDGIDSLRI 103
Query: 310 SSERLWRPDVVLLNAAATTAGDYAL--RARVSNNGSVSWIKRLDISTPISMQLDIWPNDM 483
++E +W PDVVLLN D AL VS++GSV W + S+Q+ +P D
Sbjct: 104 TAESVWLPDVVLLNNNDGNF-DVALDISVVVSSDGSVRWQPPGIYRSSCSIQVTYFPFDW 162
Query: 484 QTCTFKFGSRMHNSDEM 534
Q CT F S ++S E+
Sbjct: 163 QNCTMVFSSYSYDSSEV 179
>M86383-1|AAC84176.1| 502|Homo sapiens nicotinic acetylcholine
receptor alpha 3 subunit precursor protein.
Length = 502
Score = 64.5 bits (150), Expect = 5e-10
Identities = 33/108 (30%), Positives = 59/108 (54%), Gaps = 5/108 (4%)
Frame = +1
Query: 238 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYAL----RARVSN 402
L+ W D +L WN +G + ++ V ++++W+PD+VL N A GD+ + +A +
Sbjct: 84 LKQIWNDYKLKWNPSGYGGAEFMRVPAQKIWKPDIVLYNNAV---GDFQVTTKTKALLKY 140
Query: 403 NGSVSWIKRLDISTPISMQLDIWPNDMQTCTFKFGSRMHNSDEMDFVI 546
G V+WI + + + +P D Q CT KFGS ++ ++D V+
Sbjct: 141 TGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVL 188
>Y08421-1|CAA69698.1| 627|Homo sapiens nicotinic acetylcholine
receptor alpha4 subunit precursor protein.
Length = 627
Score = 64.1 bits (149), Expect = 7e-10
Identities = 43/156 (27%), Positives = 80/156 (51%), Gaps = 10/156 (6%)
Frame = +1
Query: 106 MIDSLLATYDRESPPDSKI--VVNLTLHLRHANIRESESTVRILAD---LQMNWIDKRLS 270
++ L + Y++ S P + I VV + L A + + + +++ ++ W D +L
Sbjct: 40 LLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLR 99
Query: 271 WNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNGSVSWIKRLD 435
W+ ++ T + + SE +WRPD+VL N A GD+A+ +A + ++G V W
Sbjct: 100 WDPADYENVTSIRIPSELIWRPDIVLYNNAD---GDFAVTHLTKAHLFHDGRVQWTPPAI 156
Query: 436 ISTPISMQLDIWPNDMQTCTFKFGSRMHNSDEMDFV 543
+ S+ + +P D Q CT KFGS ++ ++D V
Sbjct: 157 YKSSCSIDVTFFPFDQQNCTMKFGSWTYDKAKIDLV 192
>X89741-1|CAA61893.1| 627|Homo sapiens neuronal acetylcholine
receptor alpha-4 subunit protein.
Length = 627
Score = 64.1 bits (149), Expect = 7e-10
Identities = 43/156 (27%), Positives = 80/156 (51%), Gaps = 10/156 (6%)
Frame = +1
Query: 106 MIDSLLATYDRESPPDSKI--VVNLTLHLRHANIRESESTVRILAD---LQMNWIDKRLS 270
++ L + Y++ S P + I VV + L A + + + +++ ++ W D +L
Sbjct: 40 LLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLR 99
Query: 271 WNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNGSVSWIKRLD 435
W+ ++ T + + SE +WRPD+VL N A GD+A+ +A + ++G V W
Sbjct: 100 WDPADYENVTSIRIPSELIWRPDIVLYNNAD---GDFAVTHLTKAHLFHDGRVQWTPPAI 156
Query: 436 ISTPISMQLDIWPNDMQTCTFKFGSRMHNSDEMDFV 543
+ S+ + +P D Q CT KFGS ++ ++D V
Sbjct: 157 YKSSCSIDVTFFPFDQQNCTMKFGSWTYDKAKIDLV 192
>X87629-1|CAA60959.1| 602|Homo sapiens nicotinic acetylcholine
receptor protein.
Length = 602
Score = 64.1 bits (149), Expect = 7e-10
Identities = 43/156 (27%), Positives = 80/156 (51%), Gaps = 10/156 (6%)
Frame = +1
Query: 106 MIDSLLATYDRESPPDSKI--VVNLTLHLRHANIRESESTVRILAD---LQMNWIDKRLS 270
++ L + Y++ S P + I VV + L A + + + +++ ++ W D +L
Sbjct: 15 LLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLR 74
Query: 271 WNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNGSVSWIKRLD 435
W+ ++ T + + SE +WRPD+VL N A GD+A+ +A + ++G V W
Sbjct: 75 WDPADYENVTSIRIPSELIWRPDIVLYNNAD---GDFAVTHLTKAHLFHDGRVQWTPPAI 131
Query: 436 ISTPISMQLDIWPNDMQTCTFKFGSRMHNSDEMDFV 543
+ S+ + +P D Q CT KFGS ++ ++D V
Sbjct: 132 YKSSCSIDVTFFPFDQQNCTMKFGSWTYDKAKIDLV 167
>U62433-1|AAB40111.1| 627|Homo sapiens nicotinic acetylcholine
receptor alpha4 subunit precursor protein.
Length = 627
Score = 64.1 bits (149), Expect = 7e-10
Identities = 43/156 (27%), Positives = 80/156 (51%), Gaps = 10/156 (6%)
Frame = +1
Query: 106 MIDSLLATYDRESPPDSKI--VVNLTLHLRHANIRESESTVRILAD---LQMNWIDKRLS 270
++ L + Y++ S P + I VV + L A + + + +++ ++ W D +L
Sbjct: 40 LLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLR 99
Query: 271 WNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNGSVSWIKRLD 435
W+ ++ T + + SE +WRPD+VL N A GD+A+ +A + ++G V W
Sbjct: 100 WDPADYENVTSIRIPSELIWRPDIVLYNNAD---GDFAVTHLTKAHLFHDGRVQWTPPAI 156
Query: 436 ISTPISMQLDIWPNDMQTCTFKFGSRMHNSDEMDFV 543
+ S+ + +P D Q CT KFGS ++ ++D V
Sbjct: 157 YKSSCSIDVTFFPFDQQNCTMKFGSWTYDKAKIDLV 192
>L35901-1|AAA64743.1| 627|Homo sapiens nicotinic acetylcholine
receptor alpha 4 subunit protein.
Length = 627
Score = 64.1 bits (149), Expect = 7e-10
Identities = 43/156 (27%), Positives = 80/156 (51%), Gaps = 10/156 (6%)
Frame = +1
Query: 106 MIDSLLATYDRESPPDSKI--VVNLTLHLRHANIRESESTVRILAD---LQMNWIDKRLS 270
++ L + Y++ S P + I VV + L A + + + +++ ++ W D +L
Sbjct: 40 LLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLR 99
Query: 271 WNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNGSVSWIKRLD 435
W+ ++ T + + SE +WRPD+VL N A GD+A+ +A + ++G V W
Sbjct: 100 WDPADYENVTSIRIPSELIWRPDIVLYNNAD---GDFAVTHLTKAHLFHDGRVQWTPPAI 156
Query: 436 ISTPISMQLDIWPNDMQTCTFKFGSRMHNSDEMDFV 543
+ S+ + +P D Q CT KFGS ++ ++D V
Sbjct: 157 YKSSCSIDVTFFPFDQQNCTMKFGSWTYDKAKIDLV 192
>DQ093071-1|AAY88737.1| 627|Homo sapiens cholinergic receptor,
nicotinic, alpha polypeptide 4 protein.
Length = 627
Score = 64.1 bits (149), Expect = 7e-10
Identities = 43/156 (27%), Positives = 80/156 (51%), Gaps = 10/156 (6%)
Frame = +1
Query: 106 MIDSLLATYDRESPPDSKI--VVNLTLHLRHANIRESESTVRILAD---LQMNWIDKRLS 270
++ L + Y++ S P + I VV + L A + + + +++ ++ W D +L
Sbjct: 40 LLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLR 99
Query: 271 WNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNGSVSWIKRLD 435
W+ ++ T + + SE +WRPD+VL N A GD+A+ +A + ++G V W
Sbjct: 100 WDPADYENVTSIRIPSELIWRPDIVLYNNAD---GDFAVTHLTKAHLFHDGRVQWTPPAI 156
Query: 436 ISTPISMQLDIWPNDMQTCTFKFGSRMHNSDEMDFV 543
+ S+ + +P D Q CT KFGS ++ ++D V
Sbjct: 157 YKSSCSIDVTFFPFDQQNCTMKFGSWTYDKAKIDLV 192
>BC096290-1|AAH96290.1| 627|Homo sapiens cholinergic receptor,
nicotinic, alpha 4 protein.
Length = 627
Score = 64.1 bits (149), Expect = 7e-10
Identities = 43/156 (27%), Positives = 80/156 (51%), Gaps = 10/156 (6%)
Frame = +1
Query: 106 MIDSLLATYDRESPPDSKI--VVNLTLHLRHANIRESESTVRILAD---LQMNWIDKRLS 270
++ L + Y++ S P + I VV + L A + + + +++ ++ W D +L
Sbjct: 40 LLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLR 99
Query: 271 WNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNGSVSWIKRLD 435
W+ ++ T + + SE +WRPD+VL N A GD+A+ +A + ++G V W
Sbjct: 100 WDPADYENVTSIRIPSELIWRPDIVLYNNAD---GDFAVTHLTKAHLFHDGRVQWTPPAI 156
Query: 436 ISTPISMQLDIWPNDMQTCTFKFGSRMHNSDEMDFV 543
+ S+ + +P D Q CT KFGS ++ ++D V
Sbjct: 157 YKSSCSIDVTFFPFDQQNCTMKFGSWTYDKAKIDLV 192
>BC023553-1|AAH23553.1| 501|Homo sapiens cholinergic receptor,
nicotinic, beta 1 (muscle) protein.
Length = 501
Score = 64.1 bits (149), Expect = 7e-10
Identities = 45/139 (32%), Positives = 71/139 (51%), Gaps = 6/139 (4%)
Frame = +1
Query: 136 RESPPDSKIVVNLTL-HLRHANIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLV 309
RE ++ V L L L N ++ E + ++ DL+ W D RLSW+ E G + +
Sbjct: 46 REVGDRVRVSVGLILAQLISLNEKDEEMSTKVYLDLE--WTDYRLSWDPAEHDGIDSLRI 103
Query: 310 SSERLWRPDVVLLNAAATTAGDY----ALRARVSNNGSVSWIKRLDISTPISMQLDIWPN 477
++E +W PDVVLLN G++ + VS++GSV W + S+Q+ +P
Sbjct: 104 TAESVWLPDVVLLN---NNDGNFYVALDISVVVSSDGSVRWQPPGIYRSSCSIQVTYFPF 160
Query: 478 DMQTCTFKFGSRMHNSDEM 534
D Q CT F S ++S E+
Sbjct: 161 DWQNCTMVFSSYSYDSSEV 179
>X66403-1|CAA47030.1| 493|Homo sapiens acetylcholine receptor
epsilon subunit CHRNE protein.
Length = 493
Score = 63.7 bits (148), Expect = 9e-10
Identities = 36/134 (26%), Positives = 71/134 (52%), Gaps = 3/134 (2%)
Frame = +1
Query: 148 PDSKIVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEWG-CSTWLVSSER 321
P+ + ++L + L + ++ E E T+ + ++W D RL+++ ++G T V SE
Sbjct: 45 PEDTVTISLKVTLTNLISLNEKEETLTTSVWIGIDWQDYRLNYSKDDFGGIETLRVPSEL 104
Query: 322 LWRPDVVLLNAAATTAG-DYALRARVSNNGSVSWIKRLDISTPISMQLDIWPNDMQTCTF 498
+W P++VL N G Y V GSV+W+ + ++++ +P D Q C+
Sbjct: 105 VWLPEIVLENNIDGQFGVAYDANVLVYEGGSVTWLPPAIYRSVCAVEVTYFPFDWQNCSL 164
Query: 499 KFGSRMHNSDEMDF 540
F S+ +N++E++F
Sbjct: 165 IFRSQTYNAEEVEF 178
>AF105999-1|AAD24503.1| 493|Homo sapiens acetylcholine receptor
epsilon subunit protein.
Length = 493
Score = 63.7 bits (148), Expect = 9e-10
Identities = 36/134 (26%), Positives = 71/134 (52%), Gaps = 3/134 (2%)
Frame = +1
Query: 148 PDSKIVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEWG-CSTWLVSSER 321
P+ + ++L + L + ++ E E T+ + ++W D RL+++ ++G T V SE
Sbjct: 45 PEDTVTISLKVTLTNLISLNEKEETLTTSVWIGIDWQDYRLNYSKDDFGGIETLRVPSEL 104
Query: 322 LWRPDVVLLNAAATTAG-DYALRARVSNNGSVSWIKRLDISTPISMQLDIWPNDMQTCTF 498
+W P++VL N G Y V GSV+W+ + ++++ +P D Q C+
Sbjct: 105 VWLPEIVLENNIDGQFGVAYDANVLVYEGGSVTWLPPAIYRSVCAVEVTYFPFDWQNCSL 164
Query: 499 KFGSRMHNSDEMDF 540
F S+ +N++E++F
Sbjct: 165 IFRSQTYNAEEVEF 178
>X01715-1|CAA25861.1| 520|Homo sapiens acetylcholine receptor gamma
chain precursor protein.
Length = 520
Score = 61.3 bits (142), Expect = 5e-09
Identities = 43/157 (27%), Positives = 75/157 (47%), Gaps = 8/157 (5%)
Frame = +1
Query: 106 MIDSLLATYDRESPPDSKI--VVNLTLHLRHANI---RESESTVRILADLQMNWIDKRLS 270
++ L+ YD P + VVN++L L N+ E E + ++M W D RL
Sbjct: 32 LLADLMQNYDPNLRPAERDSDVVNVSLKLTLTNLISLNEREEALTTNVWIEMQWCDYRLR 91
Query: 271 WNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARV--SNNGSVSWIKRLDIS 441
W+ ++ G V S +WRPD+VL N + AL V S +G + W+
Sbjct: 92 WDPRDYEGLWVLRVPSTMVWRPDIVLENNVDGVF-EVALYCNVLVSPDGCIYWLPPAIFR 150
Query: 442 TPISMQLDIWPNDMQTCTFKFGSRMHNSDEMDFVIDK 552
+ S+ + +P D Q C+ F S+ ++++E+D + +
Sbjct: 151 SACSISVTYFPFDWQNCSLIFQSQTYSTNEIDLQLSQ 187
>AC092165-3|AAY24103.1| 520|Homo sapiens unknown protein.
Length = 520
Score = 61.3 bits (142), Expect = 5e-09
Identities = 43/157 (27%), Positives = 75/157 (47%), Gaps = 8/157 (5%)
Frame = +1
Query: 106 MIDSLLATYDRESPPDSKI--VVNLTLHLRHANI---RESESTVRILADLQMNWIDKRLS 270
++ L+ YD P + VVN++L L N+ E E + ++M W D RL
Sbjct: 32 LLADLMQNYDPNLRPAERDSDVVNVSLKLTLTNLISLNEREEALTTNVWIEMQWCDYRLR 91
Query: 271 WNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARV--SNNGSVSWIKRLDIS 441
W+ ++ G V S +WRPD+VL N + AL V S +G + W+
Sbjct: 92 WDPRDYEGLWVLRVPSTMVWRPDIVLENNVDGVF-EVALYCNVLVSPDGCIYWLPPAIFR 150
Query: 442 TPISMQLDIWPNDMQTCTFKFGSRMHNSDEMDFVIDK 552
+ S+ + +P D Q C+ F S+ ++++E+D + +
Sbjct: 151 SACSISVTYFPFDWQNCSLIFQSQTYSTNEIDLQLSQ 187
>BC113575-1|AAI13576.1| 479|Homo sapiens cholinergic receptor,
nicotinic, alpha 9 protein.
Length = 479
Score = 59.7 bits (138), Expect = 1e-08
Identities = 39/163 (23%), Positives = 76/163 (46%), Gaps = 7/163 (4%)
Frame = +1
Query: 70 AAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHANIRESESTVRILAD-- 237
AAE + + + L Y P D+ V+N+TL + + I++ + +IL
Sbjct: 22 AAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQITLSQIKDMDERNQILTAYL 81
Query: 238 -LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYA-LRARVSNNG 408
++ W D L+W+ ++ G + + S+ +WRPD+VL N A + + + +G
Sbjct: 82 WIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKADDESSEPVNTNVVLRYDG 141
Query: 409 SVSWIKRLDISTPISMQLDIWPNDMQTCTFKFGSRMHNSDEMD 537
++W + + + +P D Q C FGS +N +++D
Sbjct: 142 LITWDAPAITKSSCVVDVTYFPFDNQQCNLTFGSWTYNGNQVD 184
>BC113549-1|AAI13550.1| 479|Homo sapiens cholinergic receptor,
nicotinic, alpha 9 protein.
Length = 479
Score = 59.7 bits (138), Expect = 1e-08
Identities = 39/163 (23%), Positives = 76/163 (46%), Gaps = 7/163 (4%)
Frame = +1
Query: 70 AAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHANIRESESTVRILAD-- 237
AAE + + + L Y P D+ V+N+TL + + I++ + +IL
Sbjct: 22 AAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQITLSQIKDMDERNQILTAYL 81
Query: 238 -LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYA-LRARVSNNG 408
++ W D L+W+ ++ G + + S+ +WRPD+VL N A + + + +G
Sbjct: 82 WIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKADDESSEPVNTNVVLRYDG 141
Query: 409 SVSWIKRLDISTPISMQLDIWPNDMQTCTFKFGSRMHNSDEMD 537
++W + + + +P D Q C FGS +N +++D
Sbjct: 142 LITWDAPAITKSSCVVDVTYFPFDNQQCNLTFGSWTYNGNQVD 184
>AY123244-1|AAM74523.1| 479|Homo sapiens nicotinic acetylcholine
receptor subunit alpha 9 protein.
Length = 479
Score = 59.7 bits (138), Expect = 1e-08
Identities = 39/163 (23%), Positives = 76/163 (46%), Gaps = 7/163 (4%)
Frame = +1
Query: 70 AAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHANIRESESTVRILAD-- 237
AAE + + + L Y P D+ V+N+TL + + I++ + +IL
Sbjct: 22 AAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQITLSQIKDMDERNQILTAYL 81
Query: 238 -LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYA-LRARVSNNG 408
++ W D L+W+ ++ G + + S+ +WRPD+VL N A + + + +G
Sbjct: 82 WIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKADDESSEPVNTNVVLRYDG 141
Query: 409 SVSWIKRLDISTPISMQLDIWPNDMQTCTFKFGSRMHNSDEMD 537
++W + + + +P D Q C FGS +N +++D
Sbjct: 142 LITWDAPAITKSSCVVDVTYFPFDNQQCNLTFGSWTYNGNQVD 184
>AJ243342-1|CAB65091.1| 479|Homo sapiens nicotinic acetylcholine
receptor alpha 9 subunit protein.
Length = 479
Score = 59.7 bits (138), Expect = 1e-08
Identities = 39/163 (23%), Positives = 76/163 (46%), Gaps = 7/163 (4%)
Frame = +1
Query: 70 AAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHANIRESESTVRILAD-- 237
AAE + + + L Y P D+ V+N+TL + + I++ + +IL
Sbjct: 22 AAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQITLSQIKDMDERNQILTAYL 81
Query: 238 -LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYA-LRARVSNNG 408
++ W D L+W+ ++ G + + S+ +WRPD+VL N A + + + +G
Sbjct: 82 WIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKADDESSEPVNTNVVLRYDG 141
Query: 409 SVSWIKRLDISTPISMQLDIWPNDMQTCTFKFGSRMHNSDEMD 537
++W + + + +P D Q C FGS +N +++D
Sbjct: 142 LITWDAPAITKSSCVVDVTYFPFDNQQCNLTFGSWTYNGNQVD 184
>AF227732-1|AAF61920.1| 470|Homo sapiens nicotinic acetylcholine
receptor alpha 9 subunit protein.
Length = 470
Score = 59.7 bits (138), Expect = 1e-08
Identities = 39/163 (23%), Positives = 76/163 (46%), Gaps = 7/163 (4%)
Frame = +1
Query: 70 AAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHANIRESESTVRILAD-- 237
AAE + + + L Y P D+ V+N+TL + + I++ + +IL
Sbjct: 16 AAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQITLSQIKDMDERNQILTAYL 75
Query: 238 -LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYA-LRARVSNNG 408
++ W D L+W+ ++ G + + S+ +WRPD+VL N A + + + +G
Sbjct: 76 WIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKADDESSEPVNTNVVLRYDG 135
Query: 409 SVSWIKRLDISTPISMQLDIWPNDMQTCTFKFGSRMHNSDEMD 537
++W + + + +P D Q C FGS +N +++D
Sbjct: 136 LITWDAPAITKSSCVVDVTYFPFDNQQCNLTFGSWTYNGNQVD 178
>AC118275-1|AAY40986.1| 479|Homo sapiens unknown protein.
Length = 479
Score = 59.7 bits (138), Expect = 1e-08
Identities = 39/163 (23%), Positives = 76/163 (46%), Gaps = 7/163 (4%)
Frame = +1
Query: 70 AAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHANIRESESTVRILAD-- 237
AAE + + + L Y P D+ V+N+TL + + I++ + +IL
Sbjct: 22 AAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQITLSQIKDMDERNQILTAYL 81
Query: 238 -LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYA-LRARVSNNG 408
++ W D L+W+ ++ G + + S+ +WRPD+VL N A + + + +G
Sbjct: 82 WIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKADDESSEPVNTNVVLRYDG 141
Query: 409 SVSWIKRLDISTPISMQLDIWPNDMQTCTFKFGSRMHNSDEMD 537
++W + + + +P D Q C FGS +N +++D
Sbjct: 142 LITWDAPAITKSSCVVDVTYFPFDNQQCNLTFGSWTYNGNQVD 184
>Y08415-1|CAA69692.1| 502|Homo sapiens nicotinic acetylcholine
receptor beta2 subunit precursor protein.
Length = 502
Score = 58.8 bits (136), Expect = 2e-08
Identities = 38/132 (28%), Positives = 61/132 (46%), Gaps = 3/132 (2%)
Frame = +1
Query: 160 IVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 333
+ V L + L ++ E E + L W D RL+W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 334 DVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDIWPNDMQTCTFKFGS 510
DVVL N A + A VS +GS+ W+ + +++ +P D Q CT KF S
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRS 175
Query: 511 RMHNSDEMDFVI 546
++ E+D V+
Sbjct: 176 WTYDRTEIDLVL 187
>X53179-1|CAA37320.1| 502|Homo sapiens precursor peptide (AA -25 to
477) protein.
Length = 502
Score = 58.8 bits (136), Expect = 2e-08
Identities = 38/132 (28%), Positives = 61/132 (46%), Gaps = 3/132 (2%)
Frame = +1
Query: 160 IVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 333
+ V L + L ++ E E + L W D RL+W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 334 DVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDIWPNDMQTCTFKFGS 510
DVVL N A + A VS +GS+ W+ + +++ +P D Q CT KF S
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRS 175
Query: 511 RMHNSDEMDFVI 546
++ E+D V+
Sbjct: 176 WTYDRTEIDLVL 187
>U62437-1|AAB40115.1| 502|Homo sapiens nicotinic acetylcholine
receptor beta2 subunit precursor protein.
Length = 502
Score = 58.8 bits (136), Expect = 2e-08
Identities = 38/132 (28%), Positives = 61/132 (46%), Gaps = 3/132 (2%)
Frame = +1
Query: 160 IVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 333
+ V L + L ++ E E + L W D RL+W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 334 DVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDIWPNDMQTCTFKFGS 510
DVVL N A + A VS +GS+ W+ + +++ +P D Q CT KF S
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRS 175
Query: 511 RMHNSDEMDFVI 546
++ E+D V+
Sbjct: 176 WTYDRTEIDLVL 187
>BC075041-1|AAH75041.1| 502|Homo sapiens cholinergic receptor,
nicotinic, beta 2 (neuronal) protein.
Length = 502
Score = 58.8 bits (136), Expect = 2e-08
Identities = 38/132 (28%), Positives = 61/132 (46%), Gaps = 3/132 (2%)
Frame = +1
Query: 160 IVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 333
+ V L + L ++ E E + L W D RL+W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 334 DVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDIWPNDMQTCTFKFGS 510
DVVL N A + A VS +GS+ W+ + +++ +P D Q CT KF S
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRS 175
Query: 511 RMHNSDEMDFVI 546
++ E+D V+
Sbjct: 176 WTYDRTEIDLVL 187
>BC075040-1|AAH75040.1| 502|Homo sapiens cholinergic receptor,
nicotinic, beta 2 (neuronal) protein.
Length = 502
Score = 58.8 bits (136), Expect = 2e-08
Identities = 38/132 (28%), Positives = 61/132 (46%), Gaps = 3/132 (2%)
Frame = +1
Query: 160 IVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 333
+ V L + L ++ E E + L W D RL+W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 334 DVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDIWPNDMQTCTFKFGS 510
DVVL N A + A VS +GS+ W+ + +++ +P D Q CT KF S
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRS 175
Query: 511 RMHNSDEMDFVI 546
++ E+D V+
Sbjct: 176 WTYDRTEIDLVL 187
>AL592078-3|CAI16184.1| 502|Homo sapiens cholinergic receptor,
nicotinic, beta 2 (neuronal) protein.
Length = 502
Score = 58.8 bits (136), Expect = 2e-08
Identities = 38/132 (28%), Positives = 61/132 (46%), Gaps = 3/132 (2%)
Frame = +1
Query: 160 IVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 333
+ V L + L ++ E E + L W D RL+W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 334 DVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDIWPNDMQTCTFKFGS 510
DVVL N A + A VS +GS+ W+ + +++ +P D Q CT KF S
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRS 175
Query: 511 RMHNSDEMDFVI 546
++ E+D V+
Sbjct: 176 WTYDRTEIDLVL 187
>AJ295237-1|CAC16144.1| 450|Homo sapiens neuronal nicotinic
acetylcholine receptor subunit4 protein.
Length = 450
Score = 58.8 bits (136), Expect = 2e-08
Identities = 45/165 (27%), Positives = 73/165 (44%), Gaps = 10/165 (6%)
Frame = +1
Query: 73 AEC---ENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHANIRESESTVRILAD 237
AEC E +L L D L A Y P D+ +N+TL + + I + + ++L
Sbjct: 20 AECLGAEGRLALKLFRD-LFANYTSALRPVADTDQTLNVTLEVTLSQIIDMDERNQVLTL 78
Query: 238 ---LQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSN 402
++ W D L W+ +G + S +WRPD+VL N A A G + + +
Sbjct: 79 YLWIRQEWTDAYLRWDPNAYGGLDAIRIPSSLVWRPDIVLYNKADAQPPGSASTNVVLRH 138
Query: 403 NGSVSWIKRLDISTPISMQLDIWPNDMQTCTFKFGSRMHNSDEMD 537
+G+V W + + + +P D Q C FGS H ++D
Sbjct: 139 DGAVRWDAPAITRSSCRVDVAAFPFDAQHCGLTFGSWTHGGHQLD 183
>AJ278118-1|CAC20435.1| 450|Homo sapiens neuronal nicotinic
acetylcholine alpha10 subunit protein.
Length = 450
Score = 58.8 bits (136), Expect = 2e-08
Identities = 45/165 (27%), Positives = 73/165 (44%), Gaps = 10/165 (6%)
Frame = +1
Query: 73 AEC---ENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHANIRESESTVRILAD 237
AEC E +L L D L A Y P D+ +N+TL + + I + + ++L
Sbjct: 20 AECLGAEGRLALKLFRD-LFANYTSALRPVADTDQTLNVTLEVTLSQIIDMDERNQVLTL 78
Query: 238 ---LQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSN 402
++ W D L W+ +G + S +WRPD+VL N A A G + + +
Sbjct: 79 YLWIRQEWTDAYLRWDPNAYGGLDAIRIPSSLVWRPDIVLYNKADAQPPGSASTNVVLRH 138
Query: 403 NGSVSWIKRLDISTPISMQLDIWPNDMQTCTFKFGSRMHNSDEMD 537
+G+V W + + + +P D Q C FGS H ++D
Sbjct: 139 DGAVRWDAPAITRSSCRVDVAAFPFDAQHCGLTFGSWTHGGHQLD 183
>AJ001935-1|CAA05108.1| 504|Homo sapiens CHRNB2 protein.
Length = 504
Score = 58.8 bits (136), Expect = 2e-08
Identities = 38/132 (28%), Positives = 61/132 (46%), Gaps = 3/132 (2%)
Frame = +1
Query: 160 IVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 333
+ V L + L ++ E E + L W D RL+W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 334 DVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDIWPNDMQTCTFKFGS 510
DVVL N A + A VS +GS+ W+ + +++ +P D Q CT KF S
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRS 175
Query: 511 RMHNSDEMDFVI 546
++ E+D V+
Sbjct: 176 WTYDRTEIDLVL 187
>AF327367-1|AAK14333.1| 450|Homo sapiens nicotinic acetylcholine
receptor subunit alpha 10 protein.
Length = 450
Score = 58.8 bits (136), Expect = 2e-08
Identities = 45/165 (27%), Positives = 73/165 (44%), Gaps = 10/165 (6%)
Frame = +1
Query: 73 AEC---ENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHANIRESESTVRILAD 237
AEC E +L L D L A Y P D+ +N+TL + + I + + ++L
Sbjct: 20 AECLGAEGRLALKLFRD-LFANYTSALRPVADTDQTLNVTLEVTLSQIIDMDERNQVLTL 78
Query: 238 ---LQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSN 402
++ W D L W+ +G + S +WRPD+VL N A A G + + +
Sbjct: 79 YLWIRQEWTDAYLRWDPNAYGGLDAIRIPSSLVWRPDIVLYNKADAQPPGSASTNVVLRH 138
Query: 403 NGSVSWIKRLDISTPISMQLDIWPNDMQTCTFKFGSRMHNSDEMD 537
+G+V W + + + +P D Q C FGS H ++D
Sbjct: 139 DGAVRWDAPAITRSSCRVDVAAFPFDAQHCGLTFGSWTHGGHQLD 183
>AF199235-1|AAG00795.2| 450|Homo sapiens nicotinic acetylcholine
receptor subunit alpha 10 protein.
Length = 450
Score = 58.8 bits (136), Expect = 2e-08
Identities = 45/165 (27%), Positives = 73/165 (44%), Gaps = 10/165 (6%)
Frame = +1
Query: 73 AEC---ENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHANIRESESTVRILAD 237
AEC E +L L D L A Y P D+ +N+TL + + I + + ++L
Sbjct: 20 AECLGAEGRLALKLFRD-LFANYTSALRPVADTDQTLNVTLEVTLSQIIDMDERNQVLTL 78
Query: 238 ---LQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSN 402
++ W D L W+ +G + S +WRPD+VL N A A G + + +
Sbjct: 79 YLWIRQEWTDAYLRWDPNAYGGLDAIRIPSSLVWRPDIVLYNKADAQPPGSASTNVVLRH 138
Query: 403 NGSVSWIKRLDISTPISMQLDIWPNDMQTCTFKFGSRMHNSDEMD 537
+G+V W + + + +P D Q C FGS H ++D
Sbjct: 139 DGAVRWDAPAITRSSCRVDVAAFPFDAQHCGLTFGSWTHGGHQLD 183
>AF077186-1|AAD45422.1| 502|Homo sapiens neuronal nicotinic
acetylcholine receptor beta 2 protein.
Length = 502
Score = 58.8 bits (136), Expect = 2e-08
Identities = 38/132 (28%), Positives = 61/132 (46%), Gaps = 3/132 (2%)
Frame = +1
Query: 160 IVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 333
+ V L + L ++ E E + L W D RL+W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 334 DVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDIWPNDMQTCTFKFGS 510
DVVL N A + A VS +GS+ W+ + +++ +P D Q CT KF S
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRS 175
Query: 511 RMHNSDEMDFVI 546
++ E+D V+
Sbjct: 176 WTYDRTEIDLVL 187
>DQ644022-1|ABG35128.1| 456|Homo sapiens 5-HT3 receptor subunit E
splice variant HTR3Ea protein.
Length = 456
Score = 57.6 bits (133), Expect = 6e-08
Identities = 29/109 (26%), Positives = 54/109 (49%), Gaps = 1/109 (0%)
Frame = +1
Query: 238 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 414
L+M W + +SWN E G + ++++ LW PD+ ++ L A VSN G +
Sbjct: 91 LEMVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEGRI 150
Query: 415 SWIKRLDISTPISMQLDIWPNDMQTCTFKFGSRMHNSDEMDFVIDKRXY 561
+ K + + + ++ + +P D Q CT F S ++ D M ++K +
Sbjct: 151 RYKKPMKVDSICNLDIFYFPFDQQNCTLTFSSFLYTVDSMLLDMEKEVW 199
>BC131799-1|AAI31800.1| 447|Homo sapiens 5-hydroxytryptamine
(serotonin) receptor 3, family member C protein.
Length = 447
Score = 57.6 bits (133), Expect = 6e-08
Identities = 28/109 (25%), Positives = 55/109 (50%), Gaps = 1/109 (0%)
Frame = +1
Query: 238 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 414
+ + W + ++WN E G + V +E LW PD+ ++ + L A +S+ G +
Sbjct: 91 MDLVWDNPFINWNPKECVGINKLTVLAENLWLPDIFIVESMDVDQTPSGLTAYISSEGRI 150
Query: 415 SWIKRLDISTPISMQLDIWPNDMQTCTFKFGSRMHNSDEMDFVIDKRXY 561
+ K + +++ ++ + +P D Q CTF F S ++ D M +DK +
Sbjct: 151 KYDKPMRVTSICNLDIFYFPFDQQNCTFTFSSFLYTVDSMLLGMDKEVW 199
>BC101185-1|AAI01186.1| 374|Homo sapiens HTR3E protein protein.
Length = 374
Score = 57.6 bits (133), Expect = 6e-08
Identities = 29/109 (26%), Positives = 54/109 (49%), Gaps = 1/109 (0%)
Frame = +1
Query: 238 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 414
L+M W + +SWN E G + ++++ LW PD+ ++ L A VSN G +
Sbjct: 20 LEMVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEGRI 79
Query: 415 SWIKRLDISTPISMQLDIWPNDMQTCTFKFGSRMHNSDEMDFVIDKRXY 561
+ K + + + ++ + +P D Q CT F S ++ D M ++K +
Sbjct: 80 RYKKPMKVDSICNLDIFYFPFDQQNCTLTFSSFLYTVDSMLLDMEKEVW 128
>BC101183-1|AAI01184.1| 471|Homo sapiens 5-hydroxytryptamine
(serotonin) receptor 3, family member E protein.
Length = 471
Score = 57.6 bits (133), Expect = 6e-08
Identities = 29/109 (26%), Positives = 54/109 (49%), Gaps = 1/109 (0%)
Frame = +1
Query: 238 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 414
L+M W + +SWN E G + ++++ LW PD+ ++ L A VSN G +
Sbjct: 106 LEMVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEGRI 165
Query: 415 SWIKRLDISTPISMQLDIWPNDMQTCTFKFGSRMHNSDEMDFVIDKRXY 561
+ K + + + ++ + +P D Q CT F S ++ D M ++K +
Sbjct: 166 RYKKPMKVDSICNLDIFYFPFDQQNCTLTFSSFLYTVDSMLLDMEKEVW 214
>BC101182-1|AAI01183.1| 471|Homo sapiens 5-hydroxytryptamine
(serotonin) receptor 3, family member E protein.
Length = 471
Score = 57.6 bits (133), Expect = 6e-08
Identities = 29/109 (26%), Positives = 54/109 (49%), Gaps = 1/109 (0%)
Frame = +1
Query: 238 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 414
L+M W + +SWN E G + ++++ LW PD+ ++ L A VSN G +
Sbjct: 106 LEMVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEGRI 165
Query: 415 SWIKRLDISTPISMQLDIWPNDMQTCTFKFGSRMHNSDEMDFVIDKRXY 561
+ K + + + ++ + +P D Q CT F S ++ D M ++K +
Sbjct: 166 RYKKPMKVDSICNLDIFYFPFDQQNCTLTFSSFLYTVDSMLLDMEKEVW 214
>AY159813-1|AAO38167.2| 471|Homo sapiens 5-hydroxytryptamine
serotonin receptor 3E protein.
Length = 471
Score = 57.6 bits (133), Expect = 6e-08
Identities = 29/109 (26%), Positives = 54/109 (49%), Gaps = 1/109 (0%)
Frame = +1
Query: 238 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 414
L+M W + +SWN E G + ++++ LW PD+ ++ L A VSN G +
Sbjct: 106 LEMVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEGRI 165
Query: 415 SWIKRLDISTPISMQLDIWPNDMQTCTFKFGSRMHNSDEMDFVIDKRXY 561
+ K + + + ++ + +P D Q CT F S ++ D M ++K +
Sbjct: 166 RYKKPMKVDSICNLDIFYFPFDQQNCTLTFSSFLYTVDSMLLDMEKEVW 214
>AF459285-1|AAL66182.1| 447|Homo sapiens 5-hydroxytryptamine
receptor 3 subunit C protein.
Length = 447
Score = 57.2 bits (132), Expect = 8e-08
Identities = 28/109 (25%), Positives = 54/109 (49%), Gaps = 1/109 (0%)
Frame = +1
Query: 238 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 414
+ + W + ++WN E G + V +E LW PD+ ++ + L A +S+ G +
Sbjct: 91 MDLVWDNPFINWNPKECVGINKLTVLAENLWLPDIFIVESMDVDQTPSGLTAYISSEGRI 150
Query: 415 SWIKRLDISTPISMQLDIWPNDMQTCTFKFGSRMHNSDEMDFVIDKRXY 561
+ K + +++ + + +P D Q CTF F S ++ D M +DK +
Sbjct: 151 KYDKPMRVTSICKLDIFYFPFDQQNCTFTFSSFLYTVDSMLLGMDKEVW 199
>X55019-1|CAA38759.1| 517|Homo sapiens acetylcholine receptor delta
subunit protein.
Length = 517
Score = 56.8 bits (131), Expect = 1e-07
Identities = 38/142 (26%), Positives = 67/142 (47%), Gaps = 7/142 (4%)
Frame = +1
Query: 130 YDRESPP----DSKIVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEWG- 291
Y++E P + + V L L L + +++E E T+ ++ W D RL WNA E+G
Sbjct: 38 YNKELRPVAHKEESVDVALALTLSNLISLKEVEETLTTNVWIEHGWTDNRLKWNAEEFGN 97
Query: 292 CSTWLVSSERLWRPDVVL-LNAAATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDI 468
S + + +W P++VL N + Y+ V + G V W+ + + +
Sbjct: 98 ISVLRLPPDMVWLPEIVLENNNDGSFQISYSCNVLVYHYGFVYWLPPAIFRSSCPISVTY 157
Query: 469 WPNDMQTCTFKFGSRMHNSDEM 534
+P D Q C+ KF S + + E+
Sbjct: 158 FPFDWQNCSLKFSSLKYTAKEI 179
>BC093925-1|AAH93925.1| 517|Homo sapiens cholinergic receptor,
nicotinic, delta protein.
Length = 517
Score = 56.8 bits (131), Expect = 1e-07
Identities = 38/142 (26%), Positives = 67/142 (47%), Gaps = 7/142 (4%)
Frame = +1
Query: 130 YDRESPP----DSKIVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEWG- 291
Y++E P + + V L L L + +++E E T+ ++ W D RL WNA E+G
Sbjct: 38 YNKELRPVAHKEESVDVALALTLSNLISLKEVEETLTTNVWIEHGWTDNRLKWNAEEFGN 97
Query: 292 CSTWLVSSERLWRPDVVL-LNAAATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDI 468
S + + +W P++VL N + Y+ V + G V W+ + + +
Sbjct: 98 ISVLRLPPDMVWLPEIVLENNNDGSFQISYSCNVLVYHYGFVYWLPPAIFRSSCPISVTY 157
Query: 469 WPNDMQTCTFKFGSRMHNSDEM 534
+P D Q C+ KF S + + E+
Sbjct: 158 FPFDWQNCSLKFSSLKYTAKEI 179
>BC093923-1|AAH93923.1| 517|Homo sapiens cholinergic receptor,
nicotinic, delta protein.
Length = 517
Score = 56.8 bits (131), Expect = 1e-07
Identities = 38/142 (26%), Positives = 67/142 (47%), Gaps = 7/142 (4%)
Frame = +1
Query: 130 YDRESPP----DSKIVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEWG- 291
Y++E P + + V L L L + +++E E T+ ++ W D RL WNA E+G
Sbjct: 38 YNKELRPVAHKEESVDVALALTLSNLISLKEVEETLTTNVWIEHGWTDNRLKWNAEEFGN 97
Query: 292 CSTWLVSSERLWRPDVVL-LNAAATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDI 468
S + + +W P++VL N + Y+ V + G V W+ + + +
Sbjct: 98 ISVLRLPPDMVWLPEIVLENNNDGSFQISYSCNVLVYHYGFVYWLPPAIFRSSCPISVTY 157
Query: 469 WPNDMQTCTFKFGSRMHNSDEM 534
+P D Q C+ KF S + + E+
Sbjct: 158 FPFDWQNCSLKFSSLKYTAKEI 179
>AC092165-2|AAY24102.1| 517|Homo sapiens unknown protein.
Length = 517
Score = 56.8 bits (131), Expect = 1e-07
Identities = 38/142 (26%), Positives = 67/142 (47%), Gaps = 7/142 (4%)
Frame = +1
Query: 130 YDRESPP----DSKIVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEWG- 291
Y++E P + + V L L L + +++E E T+ ++ W D RL WNA E+G
Sbjct: 38 YNKELRPVAHKEESVDVALALTLSNLISLKEVEETLTTNVWIEHGWTDNRLKWNAEEFGN 97
Query: 292 CSTWLVSSERLWRPDVVL-LNAAATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDI 468
S + + +W P++VL N + Y+ V + G V W+ + + +
Sbjct: 98 ISVLRLPPDMVWLPEIVLENNNDGSFQISYSCNVLVYHYGFVYWLPPAIFRSSCPISVTY 157
Query: 469 WPNDMQTCTFKFGSRMHNSDEM 534
+P D Q C+ KF S + + E+
Sbjct: 158 FPFDWQNCSLKFSSLKYTAKEI 179
>Y00762-1|CAA68731.1| 457|Homo sapiens protein ( Human mRNA for
muscle acetylcholine receptor alpha-subunit. ).
Length = 457
Score = 56.0 bits (129), Expect = 2e-07
Identities = 34/123 (27%), Positives = 60/123 (48%), Gaps = 5/123 (4%)
Frame = +1
Query: 157 KIVVNLTLHLRHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRP 333
++ V L L ++ N+ E V L+ W+D L WN ++G + + SE++WRP
Sbjct: 50 EVTVGLQL-IQLINVDEVNQIVTTNVRLKQQWVDYNLKWNPDDYGGVKKIHIPSEKIWRP 108
Query: 334 DVVLLNAAATTAGDYAL----RARVSNNGSVSWIKRLDISTPISMQLDIWPNDMQTCTFK 501
D+VL N A GD+A+ + + G ++W + + + +P D Q C+ K
Sbjct: 109 DLVLYNNA---DGDFAIVKFTKVLLQYTGHITWTPPAIFKSYCEIIVTHFPFDEQNCSMK 165
Query: 502 FGS 510
G+
Sbjct: 166 LGT 168
>X02502-1|CAA26344.1| 457|Homo sapiens acetylcholine receptor
protein.
Length = 457
Score = 56.0 bits (129), Expect = 2e-07
Identities = 34/123 (27%), Positives = 60/123 (48%), Gaps = 5/123 (4%)
Frame = +1
Query: 157 KIVVNLTLHLRHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRP 333
++ V L L ++ N+ E V L+ W+D L WN ++G + + SE++WRP
Sbjct: 50 EVTVGLQL-IQLINVDEVNQIVTTNVRLKQQWVDYNLKWNPDDYGGVKKIHIPSEKIWRP 108
Query: 334 DVVLLNAAATTAGDYAL----RARVSNNGSVSWIKRLDISTPISMQLDIWPNDMQTCTFK 501
D+VL N A GD+A+ + + G ++W + + + +P D Q C+ K
Sbjct: 109 DLVLYNNA---DGDFAIVKFTKVLLQYTGHITWTPPAIFKSYCEIIVTHFPFDEQNCSMK 165
Query: 502 FGS 510
G+
Sbjct: 166 LGT 168
>S77094-1|AAD14247.1| 457|Homo sapiens nicotinic acetylcholine
receptor alpha subunit|AChR protein.
Length = 457
Score = 56.0 bits (129), Expect = 2e-07
Identities = 34/123 (27%), Positives = 60/123 (48%), Gaps = 5/123 (4%)
Frame = +1
Query: 157 KIVVNLTLHLRHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRP 333
++ V L L ++ N+ E V L+ W+D L WN ++G + + SE++WRP
Sbjct: 50 EVTVGLQL-IQLINVDEVNQIVTTNVRLKQQWVDYNLKWNPDDYGGVKKIHIPSEKIWRP 108
Query: 334 DVVLLNAAATTAGDYAL----RARVSNNGSVSWIKRLDISTPISMQLDIWPNDMQTCTFK 501
D+VL N A GD+A+ + + G ++W + + + +P D Q C+ K
Sbjct: 109 DLVLYNNA---DGDFAIVKFTKVLLQYTGHITWTPPAIFKSYCEIIVTHFPFDEQNCSMK 165
Query: 502 FGS 510
G+
Sbjct: 166 LGT 168
>BC006314-1|AAH06314.1| 269|Homo sapiens CHRNA1 protein protein.
Length = 269
Score = 56.0 bits (129), Expect = 2e-07
Identities = 34/123 (27%), Positives = 60/123 (48%), Gaps = 5/123 (4%)
Frame = +1
Query: 157 KIVVNLTLHLRHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRP 333
++ V L L ++ N+ E V L+ W+D L WN ++G + + SE++WRP
Sbjct: 50 EVTVGLQL-IQLINVDEVNQIVTTNVRLKQQWVDYNLKWNPDDYGGVKKIHIPSEKIWRP 108
Query: 334 DVVLLNAAATTAGDYAL----RARVSNNGSVSWIKRLDISTPISMQLDIWPNDMQTCTFK 501
D+VL N A GD+A+ + + G ++W + + + +P D Q C+ K
Sbjct: 109 DLVLYNNA---DGDFAIVKFTKVLLQYTGHITWTPPAIFKSYCEIIVTHFPFDEQNCSMK 165
Query: 502 FGS 510
G+
Sbjct: 166 LGT 168
>AC018890-1|AAY14687.1| 457|Homo sapiens unknown protein.
Length = 457
Score = 56.0 bits (129), Expect = 2e-07
Identities = 34/123 (27%), Positives = 60/123 (48%), Gaps = 5/123 (4%)
Frame = +1
Query: 157 KIVVNLTLHLRHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRP 333
++ V L L ++ N+ E V L+ W+D L WN ++G + + SE++WRP
Sbjct: 50 EVTVGLQL-IQLINVDEVNQIVTTNVRLKQQWVDYNLKWNPDDYGGVKKIHIPSEKIWRP 108
Query: 334 DVVLLNAAATTAGDYAL----RARVSNNGSVSWIKRLDISTPISMQLDIWPNDMQTCTFK 501
D+VL N A GD+A+ + + G ++W + + + +P D Q C+ K
Sbjct: 109 DLVLYNNA---DGDFAIVKFTKVLLQYTGHITWTPPAIFKSYCEIIVTHFPFDEQNCSMK 165
Query: 502 FGS 510
G+
Sbjct: 166 LGT 168
>AY349353-1|AAQ93477.1| 456|Homo sapiens 5-HT3c1 serotonin
receptor-like protein protein.
Length = 456
Score = 55.6 bits (128), Expect = 2e-07
Identities = 29/111 (26%), Positives = 54/111 (48%), Gaps = 1/111 (0%)
Frame = +1
Query: 232 ADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNG 408
A L + W + +SWN E G + ++++ LW PD+ ++ L A VSN G
Sbjct: 89 AILDVVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEG 148
Query: 409 SVSWIKRLDISTPISMQLDIWPNDMQTCTFKFGSRMHNSDEMDFVIDKRXY 561
+ + K + + + ++ + +P D Q CT F S ++ D M ++K +
Sbjct: 149 RIRYKKPMKVDSICNLDIFYFPFDQQNCTLTFSSFLYTVDSMLLDMEKEVW 199
>AY349352-1|AAQ93476.1| 441|Homo sapiens 5-HT3c1 serotonin
receptor-like protein protein.
Length = 441
Score = 55.6 bits (128), Expect = 2e-07
Identities = 29/111 (26%), Positives = 54/111 (48%), Gaps = 1/111 (0%)
Frame = +1
Query: 232 ADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNG 408
A L + W + +SWN E G + ++++ LW PD+ ++ L A VSN G
Sbjct: 74 AILDVVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEG 133
Query: 409 SVSWIKRLDISTPISMQLDIWPNDMQTCTFKFGSRMHNSDEMDFVIDKRXY 561
+ + K + + + ++ + +P D Q CT F S ++ D M ++K +
Sbjct: 134 RIRYKKPMKVDSICNLDIFYFPFDQQNCTLTFSSFLYTVDSMLLDMEKEVW 184
>BC110597-1|AAI10598.1| 411|Homo sapiens ligand-gated ion channel,
zinc activated 1 protein.
Length = 411
Score = 52.8 bits (121), Expect = 2e-06
Identities = 28/101 (27%), Positives = 48/101 (47%)
Frame = +1
Query: 238 LQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVS 417
L+++W+D RL+WN + E LW P + +L A D + +ARV +G V
Sbjct: 86 LRLSWLDTRLAWNTSAHPRHAITLPWESLWTPRLTILEALWVDWRDQSPQARVDQDGHVK 145
Query: 418 WIKRLDISTPISMQLDIWPNDMQTCTFKFGSRMHNSDEMDF 540
L T + +L +P D C+ F + + + E++F
Sbjct: 146 LNLALTTETNCNFELLHFPRDHSNCSLSFYALSNTAMELEF 186
>AF512521-1|AAO20969.1| 411|Homo sapiens ligand-gated ion channel
subunit protein.
Length = 411
Score = 52.8 bits (121), Expect = 2e-06
Identities = 28/101 (27%), Positives = 48/101 (47%)
Frame = +1
Query: 238 LQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVS 417
L+++W+D RL+WN + E LW P + +L A D + +ARV +G V
Sbjct: 86 LRLSWLDTRLAWNTSAHPRHAITLPWESLWTPRLTILEALWVDWRDQSPQARVDQDGHVK 145
Query: 418 WIKRLDISTPISMQLDIWPNDMQTCTFKFGSRMHNSDEMDF 540
L T + +L +P D C+ F + + + E++F
Sbjct: 146 LNLALTTETNCNFELLHFPRDHSNCSLSFYALSNTAMELEF 186
>L08485-1|AAA58490.1| 462|Homo sapiens GABA-benzodiazepine receptor
alpha-5-subunit protein.
Length = 462
Score = 52.4 bits (120), Expect = 2e-06
Identities = 39/161 (24%), Positives = 72/161 (44%), Gaps = 7/161 (4%)
Frame = +1
Query: 82 ENATSLSLMIDSLLATYDRESPPD--SKIV-VNLTLHLRHAN-IRESESTVRILADLQMN 249
+N T + ++D LL YD P +I V +++ + ++E I + +
Sbjct: 44 DNITIFTRILDGLLDGYDNRLRPGLGERITQVRTDIYVTSFGPVSDTEMEYTIDVFFRQS 103
Query: 250 WIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSW 420
W D+RL + + + ++W PD N + A + R+ ++G++ +
Sbjct: 104 WKDERLRFKGPMQRLPLNNLLASKIWTPDTFFHNGKKSIAHNMTTPNKLLRLEDDGTLLY 163
Query: 421 IKRLDISTPISMQLDIWPNDMQTCTFKFGSRMHNSDEMDFV 543
RL IS MQL+ +P D C KFGS + + E+ +V
Sbjct: 164 TMRLTISAECPMQLEDFPMDAHACPLKFGSYAYPNSEVVYV 204
>BT009830-1|AAP88832.1| 462|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 5 protein.
Length = 462
Score = 52.4 bits (120), Expect = 2e-06
Identities = 39/161 (24%), Positives = 72/161 (44%), Gaps = 7/161 (4%)
Frame = +1
Query: 82 ENATSLSLMIDSLLATYDRESPPD--SKIV-VNLTLHLRHAN-IRESESTVRILADLQMN 249
+N T + ++D LL YD P +I V +++ + ++E I + +
Sbjct: 44 DNITIFTRILDGLLDGYDNRLRPGLGERITQVRTDIYVTSFGPVSDTEMEYTIDVFFRQS 103
Query: 250 WIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSW 420
W D+RL + + + ++W PD N + A + R+ ++G++ +
Sbjct: 104 WKDERLRFKGPMQRLPLNNLLASKIWTPDTFFHNGKKSIAHNMTTPNKLLRLEDDGTLLY 163
Query: 421 IKRLDISTPISMQLDIWPNDMQTCTFKFGSRMHNSDEMDFV 543
RL IS MQL+ +P D C KFGS + + E+ +V
Sbjct: 164 TMRLTISAECPMQLEDFPMDAHACPLKFGSYAYPNSEVVYV 204
>BC113422-1|AAI13423.1| 462|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 5 protein.
Length = 462
Score = 52.4 bits (120), Expect = 2e-06
Identities = 39/161 (24%), Positives = 72/161 (44%), Gaps = 7/161 (4%)
Frame = +1
Query: 82 ENATSLSLMIDSLLATYDRESPPD--SKIV-VNLTLHLRHAN-IRESESTVRILADLQMN 249
+N T + ++D LL YD P +I V +++ + ++E I + +
Sbjct: 44 DNITIFTRILDGLLDGYDNRLRPGLGERITQVRTDIYVTSFGPVSDTEMEYTIDVFFRQS 103
Query: 250 WIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSW 420
W D+RL + + + ++W PD N + A + R+ ++G++ +
Sbjct: 104 WKDERLRFKGPMQRLPLNNLLASKIWTPDTFFHNGKKSIAHNMTTPNKLLRLEDDGTLLY 163
Query: 421 IKRLDISTPISMQLDIWPNDMQTCTFKFGSRMHNSDEMDFV 543
RL IS MQL+ +P D C KFGS + + E+ +V
Sbjct: 164 TMRLTISAECPMQLEDFPMDAHACPLKFGSYAYPNSEVVYV 204
>BC111979-1|AAI11980.1| 462|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 5, precursor protein.
Length = 462
Score = 52.4 bits (120), Expect = 2e-06
Identities = 39/161 (24%), Positives = 72/161 (44%), Gaps = 7/161 (4%)
Frame = +1
Query: 82 ENATSLSLMIDSLLATYDRESPPD--SKIV-VNLTLHLRHAN-IRESESTVRILADLQMN 249
+N T + ++D LL YD P +I V +++ + ++E I + +
Sbjct: 44 DNITIFTRILDGLLDGYDNRLRPGLGERITQVRTDIYVTSFGPVSDTEMEYTIDVFFRQS 103
Query: 250 WIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSW 420
W D+RL + + + ++W PD N + A + R+ ++G++ +
Sbjct: 104 WKDERLRFKGPMQRLPLNNLLASKIWTPDTFFHNGKKSIAHNMTTPNKLLRLEDDGTLLY 163
Query: 421 IKRLDISTPISMQLDIWPNDMQTCTFKFGSRMHNSDEMDFV 543
RL IS MQL+ +P D C KFGS + + E+ +V
Sbjct: 164 TMRLTISAECPMQLEDFPMDAHACPLKFGSYAYPNSEVVYV 204
>AB223030-1|BAE19924.1| 411|Homo sapiens ligand-gated ion-channel
receptor L2 protein.
Length = 411
Score = 52.4 bits (120), Expect = 2e-06
Identities = 28/101 (27%), Positives = 48/101 (47%)
Frame = +1
Query: 238 LQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVS 417
L+++W+D RL+WN + E LW P + +L A D + +ARV +G V
Sbjct: 86 LRLSWLDTRLAWNTSAHPRHAITLPWESLWTPRLTILEALWVDWRDQSPQARVDQDGHVK 145
Query: 418 WIKRLDISTPISMQLDIWPNDMQTCTFKFGSRMHNSDEMDF 540
L T + +L +P D C+ F + + + E++F
Sbjct: 146 LNLALATETNCNFELLHFPRDHSNCSLSFYALSNTAMELEF 186
>Z23141-1|CAA80672.1| 479|Homo sapiens cholinergic receptor,
nicotinic, alpha polypeptide 7 protein.
Length = 479
Score = 51.6 bits (118), Expect = 4e-06
Identities = 28/102 (27%), Positives = 49/102 (48%), Gaps = 2/102 (1%)
Frame = +1
Query: 238 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSNNGS 411
LQM+W D L WN E+ G T ++W+PD++L N+A + V+++G
Sbjct: 55 LQMSWTDHYLQWNVSEYPGVKTVRFPDGQIWKPDILLYNSADERFDATFHTNVLVNSSGH 114
Query: 412 VSWIKRLDISTPISMQLDIWPNDMQTCTFKFGSRMHNSDEMD 537
++ + + + +P D+Q C KFGS + +D
Sbjct: 115 CQYLPPGIFKSSCYIDVRWFPFDVQHCKLKFGSWSYGGWSLD 156
>Y08420-1|CAA69697.1| 502|Homo sapiens nicotinic acetylcholine
receptor alpha7 subunit precursor protein.
Length = 502
Score = 51.6 bits (118), Expect = 4e-06
Identities = 28/102 (27%), Positives = 49/102 (48%), Gaps = 2/102 (1%)
Frame = +1
Query: 238 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSNNGS 411
LQM+W D L WN E+ G T ++W+PD++L N+A + V+++G
Sbjct: 78 LQMSWTDHYLQWNVSEYPGVKTVRFPDGQIWKPDILLYNSADERFDATFHTNVLVNSSGH 137
Query: 412 VSWIKRLDISTPISMQLDIWPNDMQTCTFKFGSRMHNSDEMD 537
++ + + + +P D+Q C KFGS + +D
Sbjct: 138 CQYLPPGIFKSSCYIDVRWFPFDVQHCKLKFGSWSYGGWSLD 179
>X70297-1|CAA49778.1| 502|Homo sapiens neuronal nicotinic
acetylocholine receptor alpha-7 subunit protein.
Length = 502
Score = 51.6 bits (118), Expect = 4e-06
Identities = 28/102 (27%), Positives = 49/102 (48%), Gaps = 2/102 (1%)
Frame = +1
Query: 238 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSNNGS 411
LQM+W D L WN E+ G T ++W+PD++L N+A + V+++G
Sbjct: 78 LQMSWTDHYLQWNVSEYPGVKTVRFPDGQIWKPDILLYNSADERFDATFHTNVLVNSSGH 137
Query: 412 VSWIKRLDISTPISMQLDIWPNDMQTCTFKFGSRMHNSDEMD 537
++ + + + +P D+Q C KFGS + +D
Sbjct: 138 CQYLPPGIFKSSCYIDVRWFPFDVQHCKLKFGSWSYGGWSLD 179
>U62436-1|AAB40114.1| 502|Homo sapiens nicotinic acetylcholine
receptor alpha7 subunit precursor protein.
Length = 502
Score = 51.6 bits (118), Expect = 4e-06
Identities = 28/102 (27%), Positives = 49/102 (48%), Gaps = 2/102 (1%)
Frame = +1
Query: 238 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSNNGS 411
LQM+W D L WN E+ G T ++W+PD++L N+A + V+++G
Sbjct: 78 LQMSWTDHYLQWNVSEYPGVKTVRFPDGQIWKPDILLYNSADERFDATFHTNVLVNSSGH 137
Query: 412 VSWIKRLDISTPISMQLDIWPNDMQTCTFKFGSRMHNSDEMD 537
++ + + + +P D+Q C KFGS + +D
Sbjct: 138 CQYLPPGIFKSSCYIDVRWFPFDVQHCKLKFGSWSYGGWSLD 179
>M59216-1|AAA35862.1| 474|Homo sapiens gamma-aminobutyric acid
receptor beta-1 subunit protein.
Length = 474
Score = 51.6 bits (118), Expect = 4e-06
Identities = 40/169 (23%), Positives = 73/169 (43%), Gaps = 7/169 (4%)
Frame = +1
Query: 55 CAIASAAECENATSLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESESTV 222
C S E N + + +D LL YD PD + V + + + + + E
Sbjct: 23 CCAHSTNEPSNMSYVKETVDRLLKGYDIRLRPDFGGPPVDVGMRIDVASIDMVSEVNMDY 82
Query: 223 RILADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---AR 393
+ Q +W DKRLS++ + +++LW PD LN + ++ R
Sbjct: 83 TLTMYFQQSWKDKRLSYSGIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIR 142
Query: 394 VSNNGSVSWIKRLDISTPISMQLDIWPNDMQTCTFKFGSRMHNSDEMDF 540
+ +G+V + R+ + M L +P D Q CT + S + +D+++F
Sbjct: 143 LHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEF 191
>AJ586911-1|CAE52911.1| 502|Homo sapiens nicotinic acetylcholine
alpha-7 subunit protein.
Length = 502
Score = 51.6 bits (118), Expect = 4e-06
Identities = 28/102 (27%), Positives = 49/102 (48%), Gaps = 2/102 (1%)
Frame = +1
Query: 238 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSNNGS 411
LQM+W D L WN E+ G T ++W+PD++L N+A + V+++G
Sbjct: 78 LQMSWTDHYLQWNVSEYPGVKTVRFPDGQIWKPDILLYNSADERFDATFHTNVLVNSSGH 137
Query: 412 VSWIKRLDISTPISMQLDIWPNDMQTCTFKFGSRMHNSDEMD 537
++ + + + +P D+Q C KFGS + +D
Sbjct: 138 CQYLPPGIFKSSCYIDVRWFPFDVQHCKLKFGSWSYGGWSLD 179
>S77554-1|AAB33983.1| 474|Homo sapiens GABAA receptor beta 2
subunit protein.
Length = 474
Score = 51.2 bits (117), Expect = 5e-06
Identities = 41/169 (24%), Positives = 73/169 (43%), Gaps = 7/169 (4%)
Frame = +1
Query: 55 CAIASAAECENATSLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESESTV 222
CA S + N + + +D LL YD PD + V + + + + + E
Sbjct: 23 CA-QSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDIASIDMVSEVNMDY 81
Query: 223 RILADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---AR 393
+ Q W DKRLS+N + +++LW PD LN + ++ R
Sbjct: 82 TLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIR 141
Query: 394 VSNNGSVSWIKRLDISTPISMQLDIWPNDMQTCTFKFGSRMHNSDEMDF 540
+ +G+V + R+ + M L +P D Q CT + S + +D+++F
Sbjct: 142 LHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEF 190
>S77553-1|AAB33982.1| 512|Homo sapiens GABAA receptor beta 2
subunit protein.
Length = 512
Score = 51.2 bits (117), Expect = 5e-06
Identities = 41/169 (24%), Positives = 73/169 (43%), Gaps = 7/169 (4%)
Frame = +1
Query: 55 CAIASAAECENATSLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESESTV 222
CA S + N + + +D LL YD PD + V + + + + + E
Sbjct: 23 CA-QSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDIASIDMVSEVNMDY 81
Query: 223 RILADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---AR 393
+ Q W DKRLS+N + +++LW PD LN + ++ R
Sbjct: 82 TLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIR 141
Query: 394 VSNNGSVSWIKRLDISTPISMQLDIWPNDMQTCTFKFGSRMHNSDEMDF 540
+ +G+V + R+ + M L +P D Q CT + S + +D+++F
Sbjct: 142 LHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEF 190
>S67368-1|AAB29370.1| 474|Homo sapiens gamma-aminobutyric acid A
receptor beta 2 subunit protein.
Length = 474
Score = 51.2 bits (117), Expect = 5e-06
Identities = 41/169 (24%), Positives = 73/169 (43%), Gaps = 7/169 (4%)
Frame = +1
Query: 55 CAIASAAECENATSLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESESTV 222
CA S + N + + +D LL YD PD + V + + + + + E
Sbjct: 23 CA-QSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDIASIDMVSEVNMDY 81
Query: 223 RILADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---AR 393
+ Q W DKRLS+N + +++LW PD LN + ++ R
Sbjct: 82 TLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIR 141
Query: 394 VSNNGSVSWIKRLDISTPISMQLDIWPNDMQTCTFKFGSRMHNSDEMDF 540
+ +G+V + R+ + M L +P D Q CT + S + +D+++F
Sbjct: 142 LHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEF 190
>BC105639-1|AAI05640.1| 474|Homo sapiens GABRB2 protein protein.
Length = 474
Score = 51.2 bits (117), Expect = 5e-06
Identities = 41/169 (24%), Positives = 73/169 (43%), Gaps = 7/169 (4%)
Frame = +1
Query: 55 CAIASAAECENATSLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESESTV 222
CA S + N + + +D LL YD PD + V + + + + + E
Sbjct: 23 CA-QSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDIASIDMVSEVNMDY 81
Query: 223 RILADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---AR 393
+ Q W DKRLS+N + +++LW PD LN + ++ R
Sbjct: 82 TLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIR 141
Query: 394 VSNNGSVSWIKRLDISTPISMQLDIWPNDMQTCTFKFGSRMHNSDEMDF 540
+ +G+V + R+ + M L +P D Q CT + S + +D+++F
Sbjct: 142 LHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEF 190
>BC099719-1|AAH99719.1| 474|Homo sapiens GABRB2 protein protein.
Length = 474
Score = 51.2 bits (117), Expect = 5e-06
Identities = 41/169 (24%), Positives = 73/169 (43%), Gaps = 7/169 (4%)
Frame = +1
Query: 55 CAIASAAECENATSLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESESTV 222
CA S + N + + +D LL YD PD + V + + + + + E
Sbjct: 23 CA-QSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDIASIDMVSEVNMDY 81
Query: 223 RILADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---AR 393
+ Q W DKRLS+N + +++LW PD LN + ++ R
Sbjct: 82 TLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIR 141
Query: 394 VSNNGSVSWIKRLDISTPISMQLDIWPNDMQTCTFKFGSRMHNSDEMDF 540
+ +G+V + R+ + M L +P D Q CT + S + +D+++F
Sbjct: 142 LHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEF 190
>BC099705-1|AAH99705.1| 474|Homo sapiens GABRB2 protein protein.
Length = 474
Score = 51.2 bits (117), Expect = 5e-06
Identities = 41/169 (24%), Positives = 73/169 (43%), Gaps = 7/169 (4%)
Frame = +1
Query: 55 CAIASAAECENATSLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESESTV 222
CA S + N + + +D LL YD PD + V + + + + + E
Sbjct: 23 CA-QSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDIASIDMVSEVNMDY 81
Query: 223 RILADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---AR 393
+ Q W DKRLS+N + +++LW PD LN + ++ R
Sbjct: 82 TLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIR 141
Query: 394 VSNNGSVSWIKRLDISTPISMQLDIWPNDMQTCTFKFGSRMHNSDEMDF 540
+ +G+V + R+ + M L +P D Q CT + S + +D+++F
Sbjct: 142 LHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEF 190
>X14767-1|CAA32875.1| 474|Homo sapiens GABA-A receptor beta 1
subunit protein.
Length = 474
Score = 50.8 bits (116), Expect = 7e-06
Identities = 40/169 (23%), Positives = 72/169 (42%), Gaps = 7/169 (4%)
Frame = +1
Query: 55 CAIASAAECENATSLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESESTV 222
C S E N + +D LL YD PD + V + + + + + E
Sbjct: 23 CCAHSTNEPSNMPYVKETVDRLLKGYDIRLRPDFGGPPVDVGMRIDVASIDMVSEVNMDY 82
Query: 223 RILADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---AR 393
+ Q +W DKRLS++ + +++LW PD LN + ++ R
Sbjct: 83 TLTMYFQQSWKDKRLSYSGIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIR 142
Query: 394 VSNNGSVSWIKRLDISTPISMQLDIWPNDMQTCTFKFGSRMHNSDEMDF 540
+ +G+V + R+ + M L +P D Q CT + S + +D+++F
Sbjct: 143 LHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEF 191
>U40583-1|AAA83561.1| 502|Homo sapiens alpha 7 neuronal nicotinic
acetylcholine receptor protein.
Length = 502
Score = 50.4 bits (115), Expect = 9e-06
Identities = 28/102 (27%), Positives = 48/102 (47%), Gaps = 2/102 (1%)
Frame = +1
Query: 238 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSNNGS 411
LQM+W D L WN E+ G T ++W+PD++L N+A + V+ +G
Sbjct: 78 LQMSWTDHYLQWNVSEYPGVKTVRFPDGQIWKPDILLYNSADERFDATFHTNVLVNPSGH 137
Query: 412 VSWIKRLDISTPISMQLDIWPNDMQTCTFKFGSRMHNSDEMD 537
++ + + + +P D+Q C KFGS + +D
Sbjct: 138 CQYLPPGIFKSSCYIDVRWFPFDVQHCKLKFGSWSYGGWSLD 179
>AF385585-1|AAK68111.1| 502|Homo sapiens nicotinic cholinergic
receptor alpha 7 protein.
Length = 502
Score = 50.4 bits (115), Expect = 9e-06
Identities = 28/102 (27%), Positives = 48/102 (47%), Gaps = 2/102 (1%)
Frame = +1
Query: 238 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSNNGS 411
LQM+W D L WN E+ G T ++W+PD++L N+A + V+ +G
Sbjct: 78 LQMSWTDHYLQWNVSEYPGVKTVRFPDGQIWKPDILLYNSADERFDATFHTNVLVNPSGH 137
Query: 412 VSWIKRLDISTPISMQLDIWPNDMQTCTFKFGSRMHNSDEMD 537
++ + + + +P D+Q C KFGS + +D
Sbjct: 138 CQYLPPGIFKSSCYIDVRWFPFDVQHCKLKFGSWSYGGWSLD 179
>BC111802-1|AAI11803.1| 465|Homo sapiens CHRNG protein protein.
Length = 465
Score = 49.6 bits (113), Expect = 2e-05
Identities = 33/113 (29%), Positives = 54/113 (47%), Gaps = 7/113 (6%)
Frame = +1
Query: 106 MIDSLLATYDRESPPDSKI--VVNLTLHLRHANI---RESESTVRILADLQMNWIDKRLS 270
++ L+ YD P + VVN++L L N+ E E + ++M W D RL
Sbjct: 29 LLADLMQNYDPNLRPAERDSDVVNVSLKLTLTNLISLNEREEALTTNVWIEMQWCDYRLR 88
Query: 271 WNAGEW-GCSTWLVSSERLWRPDVVLLNAAAT-TAGDYALRARVSNNGSVSWI 423
W+ ++ G V S +WRPD+VL N + T + + L+ + S+ WI
Sbjct: 89 WDPRDYEGLWVLRVPSTMVWRPDIVLENKSQTYSTNEIDLQLSQEDGQSIEWI 141
>BC028629-1|AAH28629.1| 492|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 3 protein.
Length = 492
Score = 49.6 bits (113), Expect = 2e-05
Identities = 36/158 (22%), Positives = 69/158 (43%), Gaps = 7/158 (4%)
Frame = +1
Query: 82 ENATSLSLMIDSLLATYDRESPP---DSKIVVNLTLHLRHAN-IRESESTVRILADLQMN 249
+N T + ++D LL YD P D+ V +++ + +++ I +
Sbjct: 62 DNITIFTRILDRLLDGYDNRLRPGLGDAVTEVKTDIYVTSFGPVSDTDMEYTIDVFFRQT 121
Query: 250 WIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSW 420
W D+RL ++ + + ++W PD N + A + R+ +NG++ +
Sbjct: 122 WHDERLKFDGPMKILPLNNLLASKIWTPDTFFHNGKKSVAHNMTTPNKLLRLVDNGTLPY 181
Query: 421 IKRLDISTPISMQLDIWPNDMQTCTFKFGSRMHNSDEM 534
RL I M L+ +P D+ C KFGS + + E+
Sbjct: 182 TMRLTIHAECPMHLEDFPMDVHACPLKFGSYAYTTAEV 219
>S62908-1|AAB27279.1| 492|Homo sapiens gamma-aminobutyric acidA
receptor alpha 3 subunit protein.
Length = 492
Score = 49.2 bits (112), Expect = 2e-05
Identities = 36/158 (22%), Positives = 69/158 (43%), Gaps = 7/158 (4%)
Frame = +1
Query: 82 ENATSLSLMIDSLLATYDRESPP---DSKIVVNLTLHLRHAN-IRESESTVRILADLQMN 249
+N T + ++D LL YD P D+ V +++ + +++ I +
Sbjct: 62 DNITIFTRILDRLLDGYDNRLRPGLGDAVTEVKTDIYVTSFGPVSDTDMEYTIDVFFRQT 121
Query: 250 WIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSW 420
W D+RL ++ + + ++W PD N + A + R+ +NG++ +
Sbjct: 122 WHDERLKFDGPMKILPLNNLLASKIWTPDTFFHNGKKSVAHNMTTPNKLLRLVDNGTLLY 181
Query: 421 IKRLDISTPISMQLDIWPNDMQTCTFKFGSRMHNSDEM 534
RL I M L+ +P D+ C KFGS + + E+
Sbjct: 182 TMRLTIHAECPMHLEDFPMDVHACPLKFGSYAYTTAEV 219
>AK122638-1|BAC85499.1| 266|Homo sapiens yte protein of 76kDa)
(LCP2). protein.
Length = 266
Score = 49.2 bits (112), Expect = 2e-05
Identities = 26/89 (29%), Positives = 41/89 (46%)
Frame = +1
Query: 238 LQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVS 417
L+++W+D RL+WN + E LW P + +L A D + +ARV +G V
Sbjct: 87 LRLSWLDTRLAWNTSAHPRHAITLPWESLWTPRLTILEALWVDWRDQSPQARVDQDGHVK 146
Query: 418 WIKRLDISTPISMQLDIWPNDMQTCTFKF 504
L T + +L +P D C+ F
Sbjct: 147 LNLALTTETNCNFELLHFPRDHSNCSLSF 175
>AF166361-1|AAG12455.1| 492|Homo sapiens GABA receptor subunit
alpha 3 protein.
Length = 492
Score = 49.2 bits (112), Expect = 2e-05
Identities = 36/158 (22%), Positives = 69/158 (43%), Gaps = 7/158 (4%)
Frame = +1
Query: 82 ENATSLSLMIDSLLATYDRESPP---DSKIVVNLTLHLRHAN-IRESESTVRILADLQMN 249
+N T + ++D LL YD P D+ V +++ + +++ I +
Sbjct: 62 DNITIFTRILDRLLDGYDNRLRPGLGDAVTEVKTDIYVTSFGPVSDTDMEYTIDVFFRQT 121
Query: 250 WIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSW 420
W D+RL ++ + + ++W PD N + A + R+ +NG++ +
Sbjct: 122 WHDERLKFDGPMKILPLNNLLASKIWTPDTFFHNGKKSVAHNMTTPNKLLRLVDNGTLLY 181
Query: 421 IKRLDISTPISMQLDIWPNDMQTCTFKFGSRMHNSDEM 534
RL I M L+ +P D+ C KFGS + + E+
Sbjct: 182 TMRLTIHAECPMHLEDFPMDVHACPLKFGSYAYTTAEV 219
>U30461-1|AAB52519.1| 554|Homo sapiens GABAA receptor subunit
alpha4 protein.
Length = 554
Score = 46.8 bits (106), Expect = 1e-04
Identities = 32/119 (26%), Positives = 51/119 (42%), Gaps = 3/119 (2%)
Frame = +1
Query: 205 ESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYAL 384
E E T+ + + WIDKRL ++ + ++W PD N + + +
Sbjct: 90 EMEYTMDVF--FRQTWIDKRLKYDGPIEILRLNNMMVTKVWTPDTFFRNGKKSVSHNMTA 147
Query: 385 RA---RVSNNGSVSWIKRLDISTPISMQLDIWPNDMQTCTFKFGSRMHNSDEMDFVIDK 552
R+ NG++ + RL IS M+L +P D C KFGS + EM + K
Sbjct: 148 PNKLFRIMRNGTILYTMRLTISAECPMRLVDFPMDGHACPLKFGSYAYPKSEMIYTWTK 206
>BC035055-1|AAH35055.1| 554|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 4 protein.
Length = 554
Score = 46.8 bits (106), Expect = 1e-04
Identities = 32/119 (26%), Positives = 51/119 (42%), Gaps = 3/119 (2%)
Frame = +1
Query: 205 ESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYAL 384
E E T+ + + WIDKRL ++ + ++W PD N + + +
Sbjct: 90 EMEYTMDVF--FRQTWIDKRLKYDGPIEILRLNNMMVTKVWTPDTFFRNGKKSVSHNMTA 147
Query: 385 RA---RVSNNGSVSWIKRLDISTPISMQLDIWPNDMQTCTFKFGSRMHNSDEMDFVIDK 552
R+ NG++ + RL IS M+L +P D C KFGS + EM + K
Sbjct: 148 PNKLFRIMRNGTILYTMRLTISAECPMRLVDFPMDGHACPLKFGSYAYPKSEMIYTWTK 206
>U77731-2|AAB38273.1| 360|Homo sapiens glycine receptor alpha 2B
subunit protein.
Length = 360
Score = 46.4 bits (105), Expect = 1e-04
Identities = 38/145 (26%), Positives = 64/145 (44%), Gaps = 8/145 (5%)
Frame = +1
Query: 130 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 297
YD P+ K VN+T ++ +I E+ R+ L+ W D RL+++
Sbjct: 58 YDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDSRLAYSEYPDDSL 117
Query: 298 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLD 465
S + +W+PD+ N D R+S NG V + RL ++ M L
Sbjct: 118 DLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLK 177
Query: 466 IWPNDMQTCTFKFGSRMHNSDEMDF 540
+P D+QTCT + S + +++ F
Sbjct: 178 NFPMDVQTCTMQLESFGYTMNDLIF 202
>CR450343-1|CAG29339.1| 452|Homo sapiens GLRA2 protein.
Length = 452
Score = 46.4 bits (105), Expect = 1e-04
Identities = 38/145 (26%), Positives = 64/145 (44%), Gaps = 8/145 (5%)
Frame = +1
Query: 130 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 297
YD P+ K VN+T ++ +I E+ R+ L+ W D RL+++
Sbjct: 58 YDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDSRLAYSEYPDDSL 117
Query: 298 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLD 465
S + +W+PD+ N D R+S NG V + RL ++ M L
Sbjct: 118 DLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLK 177
Query: 466 IWPNDMQTCTFKFGSRMHNSDEMDF 540
+P D+QTCT + S + +++ F
Sbjct: 178 NFPMDVQTCTMQLESFGYTMNDLIF 202
>BC096083-1|AAH96083.1| 198|Homo sapiens CHRNB4 protein protein.
Length = 198
Score = 46.4 bits (105), Expect = 1e-04
Identities = 30/115 (26%), Positives = 54/115 (46%), Gaps = 8/115 (6%)
Frame = +1
Query: 58 AIASAAECENATSLSLMIDSLL--ATYDRESPP--DSKIVVNLTLHLRHA---NIRESES 216
A+ C A + ++D LL Y+ P S ++++ L L A ++ E E
Sbjct: 14 ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQ 73
Query: 217 TVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDY 378
+ L+ W D RL+WN+ + G + + ++R+W PD+VL N + T +
Sbjct: 74 IMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNKSLRTGSTW 128
>BC096081-1|AAH96081.1| 198|Homo sapiens CHRNB4 protein protein.
Length = 198
Score = 46.4 bits (105), Expect = 1e-04
Identities = 30/115 (26%), Positives = 54/115 (46%), Gaps = 8/115 (6%)
Frame = +1
Query: 58 AIASAAECENATSLSLMIDSLL--ATYDRESPP--DSKIVVNLTLHLRHA---NIRESES 216
A+ C A + ++D LL Y+ P S ++++ L L A ++ E E
Sbjct: 14 ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQ 73
Query: 217 TVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDY 378
+ L+ W D RL+WN+ + G + + ++R+W PD+VL N + T +
Sbjct: 74 IMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNKSLRTGSTW 128
>BC022449-1|AAH22449.1| 474|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, beta 1 protein.
Length = 474
Score = 46.4 bits (105), Expect = 1e-04
Identities = 39/169 (23%), Positives = 72/169 (42%), Gaps = 7/169 (4%)
Frame = +1
Query: 55 CAIASAAECENATSLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESESTV 222
C S E N + + +D LL YD PD + V + + + + + E
Sbjct: 23 CCAHSTNEPSNMSYVKETVDRLLKGYDIRLRPDFGGPPVDVGMRIDVASIDMVSEVNMDY 82
Query: 223 RILADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---AR 393
+ Q +W DKRLS++ + +++L PD LN + ++ R
Sbjct: 83 TLTMYFQQSWKDKRLSYSGIPLNLTLDNRVADQLCVPDTYFLNDKKSFVHGVTVKNRMIR 142
Query: 394 VSNNGSVSWIKRLDISTPISMQLDIWPNDMQTCTFKFGSRMHNSDEMDF 540
+ +G+V + R+ + M L +P D Q CT + S + +D+++F
Sbjct: 143 LHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEF 191
>AY437084-1|AAR87843.1| 452|Homo sapiens glycine receptor alpha2
subunit B protein.
Length = 452
Score = 46.4 bits (105), Expect = 1e-04
Identities = 38/145 (26%), Positives = 64/145 (44%), Gaps = 8/145 (5%)
Frame = +1
Query: 130 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 297
YD P+ K VN+T ++ +I E+ R+ L+ W D RL+++
Sbjct: 58 YDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDSRLAYSEYPDDSL 117
Query: 298 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLD 465
S + +W+PD+ N D R+S NG V + RL ++ M L
Sbjct: 118 DLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLK 177
Query: 466 IWPNDMQTCTFKFGSRMHNSDEMDF 540
+P D+QTCT + S + +++ F
Sbjct: 178 NFPMDVQTCTMQLESFGYTMNDLIF 202
>AJ003080-1|CAA05853.1| 238|Homo sapiens serotonin receptor
protein.
Length = 238
Score = 46.4 bits (105), Expect = 1e-04
Identities = 26/111 (23%), Positives = 48/111 (43%), Gaps = 1/111 (0%)
Frame = +1
Query: 196 NIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAG 372
N+ E + + W D+ L WN ++ T L + ++ +W PD+++
Sbjct: 72 NVDEKNQVLTTYIWYRQYWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKS 131
Query: 373 DYALRARVSNNGSVSWIKRLDISTPISMQLDIWPNDMQTCTFKFGSRMHNS 525
+ + G V K L + T S+ + +P D+Q C+ F S +H S
Sbjct: 132 PNIPYVYIRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLHTS 182
>X52008-1|CAA36257.1| 452|Homo sapiens inhibitory glycine receptor
protein.
Length = 452
Score = 46.0 bits (104), Expect = 2e-04
Identities = 37/145 (25%), Positives = 64/145 (44%), Gaps = 8/145 (5%)
Frame = +1
Query: 130 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 297
YD P+ K VN+T ++ ++ E+ R+ L+ W D RL+++
Sbjct: 58 YDARIRPNFKGPPVNVTCNIFINSFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPDDSL 117
Query: 298 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLD 465
S + +W+PD+ N D R+S NG V + RL ++ M L
Sbjct: 118 DLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLK 177
Query: 466 IWPNDMQTCTFKFGSRMHNSDEMDF 540
+P D+QTCT + S + +++ F
Sbjct: 178 NFPMDVQTCTMQLESFGYTMNDLIF 202
>U77731-1|AAB38272.1| 360|Homo sapiens glycine receptor alpha 2
subunit protein.
Length = 360
Score = 46.0 bits (104), Expect = 2e-04
Identities = 37/145 (25%), Positives = 64/145 (44%), Gaps = 8/145 (5%)
Frame = +1
Query: 130 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 297
YD P+ K VN+T ++ ++ E+ R+ L+ W D RL+++
Sbjct: 58 YDARIRPNFKGPPVNVTCNIFINSFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPDDSL 117
Query: 298 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLD 465
S + +W+PD+ N D R+S NG V + RL ++ M L
Sbjct: 118 DLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLK 177
Query: 466 IWPNDMQTCTFKFGSRMHNSDEMDF 540
+P D+QTCT + S + +++ F
Sbjct: 178 NFPMDVQTCTMQLESFGYTMNDLIF 202
>BC032864-1|AAH32864.1| 452|Homo sapiens glycine receptor, alpha 2
protein.
Length = 452
Score = 46.0 bits (104), Expect = 2e-04
Identities = 37/145 (25%), Positives = 64/145 (44%), Gaps = 8/145 (5%)
Frame = +1
Query: 130 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 297
YD P+ K VN+T ++ ++ E+ R+ L+ W D RL+++
Sbjct: 58 YDARIRPNFKGPPVNVTCNIFINSFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPDDSL 117
Query: 298 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLD 465
S + +W+PD+ N D R+S NG V + RL ++ M L
Sbjct: 118 DLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLK 177
Query: 466 IWPNDMQTCTFKFGSRMHNSDEMDF 540
+P D+QTCT + S + +++ F
Sbjct: 178 NFPMDVQTCTMQLESFGYTMNDLIF 202
>AY437083-1|AAR87842.1| 452|Homo sapiens glycine receptor alpha2
subunit A protein.
Length = 452
Score = 46.0 bits (104), Expect = 2e-04
Identities = 37/145 (25%), Positives = 64/145 (44%), Gaps = 8/145 (5%)
Frame = +1
Query: 130 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 297
YD P+ K VN+T ++ ++ E+ R+ L+ W D RL+++
Sbjct: 58 YDARIRPNFKGPPVNVTCNIFINSFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPDDSL 117
Query: 298 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLD 465
S + +W+PD+ N D R+S NG V + RL ++ M L
Sbjct: 118 DLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLK 177
Query: 466 IWPNDMQTCTFKFGSRMHNSDEMDF 540
+P D+QTCT + S + +++ F
Sbjct: 178 NFPMDVQTCTMQLESFGYTMNDLIF 202
>AF053495-1|AAC35290.1| 452|Homo sapiens glycine receptor alpha 2
subunit protein.
Length = 452
Score = 46.0 bits (104), Expect = 2e-04
Identities = 37/145 (25%), Positives = 64/145 (44%), Gaps = 8/145 (5%)
Frame = +1
Query: 130 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 297
YD P+ K VN+T ++ ++ E+ R+ L+ W D RL+++
Sbjct: 58 YDARIRPNFKGPPVNVTCNIFINSFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPDDSL 117
Query: 298 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLD 465
S + +W+PD+ N D R+S NG V + RL ++ M L
Sbjct: 118 DLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLK 177
Query: 466 IWPNDMQTCTFKFGSRMHNSDEMDF 540
+P D+QTCT + S + +++ F
Sbjct: 178 NFPMDVQTCTMQLESFGYTMNDLIF 202
>U95367-1|AAC51357.1| 440|Homo sapiens GABA-A receptor pi subunit
protein.
Length = 440
Score = 45.6 bits (103), Expect = 2e-04
Identities = 40/164 (24%), Positives = 78/164 (47%), Gaps = 9/164 (5%)
Frame = +1
Query: 76 ECENATSLSLM-IDSLLATYDRESPPD---SKIVVNLTLHLRH-ANIRESESTVRILADL 240
E + LSL ++L A Y++ P+ + + LTL + ++I ES L
Sbjct: 29 EVGRSDKLSLPGFENLTAGYNKFLRPNFGGEPVQIALTLDIASISSISESNMDYTATIYL 88
Query: 241 QMNWIDKRLSWNAGE-WGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNG 408
+ W+D+RL + + + LV E LW PD ++ + + + + R+ +NG
Sbjct: 89 RQRWMDQRLVFEGNKSFTLDARLV--EFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNG 146
Query: 409 SVSWIKRLDISTPISMQLDIWPNDMQTCTFKFGSRMHNSDEMDF 540
+V + R+ + +M L +P D QTC + S ++ ++++F
Sbjct: 147 TVLYALRITTTVACNMDLSKYPMDTQTCKLQLESWGYDGNDVEF 190
>BC109211-1|AAI09212.1| 632|Homo sapiens gamma-aminobutyric acid
(GABA) receptor, theta protein.
Length = 632
Score = 45.6 bits (103), Expect = 2e-04
Identities = 35/145 (24%), Positives = 60/145 (41%), Gaps = 7/145 (4%)
Frame = +1
Query: 79 CENATSLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESESTVRILADLQM 246
C N + ++D +L+ YD P+ + + V +++++ I E I
Sbjct: 53 CANEAVVQKILDRVLSRYDVRLRPNFGGAPVPVRISIYVTSIEQISEMNMDYTITMFFHQ 112
Query: 247 NWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSN---NGSVS 417
W D RL++ + E+LW PD LN+ D + RV +G+V
Sbjct: 113 TWKDSRLAYYETTLNLTLDYRMHEKLWVPDCYFLNSKDAFVHDVTVENRVFQLHPDGTVR 172
Query: 418 WIKRLDISTPISMQLDIWPNDMQTC 492
+ RL + S+ L +P D Q C
Sbjct: 173 YGIRLTTTAACSLDLHKFPMDKQAC 197
>BC109210-1|AAI09211.1| 632|Homo sapiens gamma-aminobutyric acid
(GABA) receptor, theta protein.
Length = 632
Score = 45.6 bits (103), Expect = 2e-04
Identities = 35/145 (24%), Positives = 60/145 (41%), Gaps = 7/145 (4%)
Frame = +1
Query: 79 CENATSLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESESTVRILADLQM 246
C N + ++D +L+ YD P+ + + V +++++ I E I
Sbjct: 53 CANEAVVQKILDRVLSRYDVRLRPNFGGAPVPVRISIYVTSIEQISEMNMDYTITMFFHQ 112
Query: 247 NWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSN---NGSVS 417
W D RL++ + E+LW PD LN+ D + RV +G+V
Sbjct: 113 TWKDSRLAYYETTLNLTLDYRMHEKLWVPDCYFLNSKDAFVHDVTVENRVFQLHPDGTVR 172
Query: 418 WIKRLDISTPISMQLDIWPNDMQTC 492
+ RL + S+ L +P D Q C
Sbjct: 173 YGIRLTTTAACSLDLHKFPMDKQAC 197
>BC109106-1|AAI09107.1| 440|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, pi protein.
Length = 440
Score = 45.6 bits (103), Expect = 2e-04
Identities = 40/164 (24%), Positives = 78/164 (47%), Gaps = 9/164 (5%)
Frame = +1
Query: 76 ECENATSLSLM-IDSLLATYDRESPPD---SKIVVNLTLHLRH-ANIRESESTVRILADL 240
E + LSL ++L A Y++ P+ + + LTL + ++I ES L
Sbjct: 29 EVGRSDKLSLPGFENLTAGYNKFLRPNFGGEPVQIALTLDIASISSISESNMDYTATIYL 88
Query: 241 QMNWIDKRLSWNAGE-WGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNG 408
+ W+D+RL + + + LV E LW PD ++ + + + + R+ +NG
Sbjct: 89 RQRWMDQRLVFEGNKSFTLDARLV--EFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNG 146
Query: 409 SVSWIKRLDISTPISMQLDIWPNDMQTCTFKFGSRMHNSDEMDF 540
+V + R+ + +M L +P D QTC + S ++ ++++F
Sbjct: 147 TVLYALRITTTVACNMDLSKYPMDTQTCKLQLESWGYDGNDVEF 190
>BC109105-1|AAI09106.1| 440|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, pi protein.
Length = 440
Score = 45.6 bits (103), Expect = 2e-04
Identities = 40/164 (24%), Positives = 78/164 (47%), Gaps = 9/164 (5%)
Frame = +1
Query: 76 ECENATSLSLM-IDSLLATYDRESPPD---SKIVVNLTLHLRH-ANIRESESTVRILADL 240
E + LSL ++L A Y++ P+ + + LTL + ++I ES L
Sbjct: 29 EVGRSDKLSLPGFENLTAGYNKFLRPNFGGEPVQIALTLDIASISSISESNMDYTATIYL 88
Query: 241 QMNWIDKRLSWNAGE-WGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNG 408
+ W+D+RL + + + LV E LW PD ++ + + + + R+ +NG
Sbjct: 89 RQRWMDQRLVFEGNKSFTLDARLV--EFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNG 146
Query: 409 SVSWIKRLDISTPISMQLDIWPNDMQTCTFKFGSRMHNSDEMDF 540
+V + R+ + +M L +P D QTC + S ++ ++++F
Sbjct: 147 TVLYALRITTTVACNMDLSKYPMDTQTCKLQLESWGYDGNDVEF 190
>BC074865-1|AAH74865.1| 440|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, pi protein.
Length = 440
Score = 45.6 bits (103), Expect = 2e-04
Identities = 40/164 (24%), Positives = 78/164 (47%), Gaps = 9/164 (5%)
Frame = +1
Query: 76 ECENATSLSLM-IDSLLATYDRESPPD---SKIVVNLTLHLRH-ANIRESESTVRILADL 240
E + LSL ++L A Y++ P+ + + LTL + ++I ES L
Sbjct: 29 EVGRSDKLSLPGFENLTAGYNKFLRPNFGGEPVQIALTLDIASISSISESNMDYTATIYL 88
Query: 241 QMNWIDKRLSWNAGE-WGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNG 408
+ W+D+RL + + + LV E LW PD ++ + + + + R+ +NG
Sbjct: 89 RQRWMDQRLVFEGNKSFTLDARLV--EFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNG 146
Query: 409 SVSWIKRLDISTPISMQLDIWPNDMQTCTFKFGSRMHNSDEMDF 540
+V + R+ + +M L +P D QTC + S ++ ++++F
Sbjct: 147 TVLYALRITTTVACNMDLSKYPMDTQTCKLQLESWGYDGNDVEF 190
>BC074810-1|AAH74810.1| 440|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, pi protein.
Length = 440
Score = 45.6 bits (103), Expect = 2e-04
Identities = 40/164 (24%), Positives = 78/164 (47%), Gaps = 9/164 (5%)
Frame = +1
Query: 76 ECENATSLSLM-IDSLLATYDRESPPD---SKIVVNLTLHLRH-ANIRESESTVRILADL 240
E + LSL ++L A Y++ P+ + + LTL + ++I ES L
Sbjct: 29 EVGRSDKLSLPGFENLTAGYNKFLRPNFGGEPVQIALTLDIASISSISESNMDYTATIYL 88
Query: 241 QMNWIDKRLSWNAGE-WGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNG 408
+ W+D+RL + + + LV E LW PD ++ + + + + R+ +NG
Sbjct: 89 RQRWMDQRLVFEGNKSFTLDARLV--EFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNG 146
Query: 409 SVSWIKRLDISTPISMQLDIWPNDMQTCTFKFGSRMHNSDEMDF 540
+V + R+ + +M L +P D QTC + S ++ ++++F
Sbjct: 147 TVLYALRITTTVACNMDLSKYPMDTQTCKLQLESWGYDGNDVEF 190
>BC033801-1|AAH33801.1| 452|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, delta protein.
Length = 452
Score = 45.6 bits (103), Expect = 2e-04
Identities = 38/149 (25%), Positives = 64/149 (42%), Gaps = 7/149 (4%)
Frame = +1
Query: 109 IDSLLATYDRESPPD-SKIVVNLTLHLRHANI---RESESTVRILADLQMNWIDKRLSWN 276
+D L+A Y R P VN+ L L A+I E+ + L +W D RLS+N
Sbjct: 44 LDGLIAGYARNFRPGIGGPPVNVALALEVASIDHISEANMEYTMTVFLHQSWRDSRLSYN 103
Query: 277 AGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTP 447
++LW PD ++NA + D + R+ +G + + R+ +
Sbjct: 104 HTNETLGLDSRFVDKLWLPDTFIVNAKSAWFHDVTVENKLIRLQPDGVILYSIRITSTVA 163
Query: 448 ISMQLDIWPNDMQTCTFKFGSRMHNSDEM 534
M L +P D Q C S ++S+++
Sbjct: 164 CDMDLAKYPMDEQECMLDLESYGYSSEDI 192
>AL391845-4|CAI15436.1| 452|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, delta protein.
Length = 452
Score = 45.6 bits (103), Expect = 2e-04
Identities = 38/149 (25%), Positives = 64/149 (42%), Gaps = 7/149 (4%)
Frame = +1
Query: 109 IDSLLATYDRESPPD-SKIVVNLTLHLRHANI---RESESTVRILADLQMNWIDKRLSWN 276
+D L+A Y R P VN+ L L A+I E+ + L +W D RLS+N
Sbjct: 44 LDGLIAGYARNFRPGIGGPPVNVALALEVASIDHISEANMEYTMTVFLHQSWRDSRLSYN 103
Query: 277 AGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTP 447
++LW PD ++NA + D + R+ +G + + R+ +
Sbjct: 104 HTNETLGLDSRFVDKLWLPDTFIVNAKSAWFHDVTVENKLIRLQPDGVILYSIRITSTVA 163
Query: 448 ISMQLDIWPNDMQTCTFKFGSRMHNSDEM 534
M L +P D Q C S ++S+++
Sbjct: 164 CDMDLAKYPMDEQECMLDLESYGYSSEDI 192
>AF189259-1|AAF70380.1| 632|Homo sapiens GABA-A receptor theta
subunit protein.
Length = 632
Score = 45.6 bits (103), Expect = 2e-04
Identities = 35/145 (24%), Positives = 60/145 (41%), Gaps = 7/145 (4%)
Frame = +1
Query: 79 CENATSLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESESTVRILADLQM 246
C N + ++D +L+ YD P+ + + V +++++ I E I
Sbjct: 53 CANEAVVQKILDRVLSRYDVRLRPNFGGAPVPVRISIYVTSIEQISEMNMDYTITMFFHQ 112
Query: 247 NWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSN---NGSVS 417
W D RL++ + E+LW PD LN+ D + RV +G+V
Sbjct: 113 TWKDSRLAYYETTLNLTLDYRMHEKLWVPDCYFLNSKDAFVHDVTVENRVFQLHPDGTVR 172
Query: 418 WIKRLDISTPISMQLDIWPNDMQTC 492
+ RL + S+ L +P D Q C
Sbjct: 173 YGIRLTTTAACSLDLHKFPMDKQAC 197
>AF144648-1|AAD51172.1| 627|Homo sapiens GABA-A receptor theta
protein.
Length = 627
Score = 45.6 bits (103), Expect = 2e-04
Identities = 35/145 (24%), Positives = 60/145 (41%), Gaps = 7/145 (4%)
Frame = +1
Query: 79 CENATSLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESESTVRILADLQM 246
C N + ++D +L+ YD P+ + + V +++++ I E I
Sbjct: 48 CANEAVVQKILDRVLSRYDVRLRPNFGGAPVPVRISIYVTSIEQISEMNMDYTITMFFHQ 107
Query: 247 NWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSN---NGSVS 417
W D RL++ + E+LW PD LN+ D + RV +G+V
Sbjct: 108 TWKDSRLAYYETTLNLTLDYRMHEKLWVPDCYFLNSKDAFVHDVTVENRVFQLHPDGTVR 167
Query: 418 WIKRLDISTPISMQLDIWPNDMQTC 492
+ RL + S+ L +P D Q C
Sbjct: 168 YGIRLTTTAACSLDLHKFPMDKQAC 192
>AF016917-1|AAB70007.1| 452|Homo sapiens GABA-A receptor delta
subunit protein.
Length = 452
Score = 45.6 bits (103), Expect = 2e-04
Identities = 38/149 (25%), Positives = 64/149 (42%), Gaps = 7/149 (4%)
Frame = +1
Query: 109 IDSLLATYDRESPPD-SKIVVNLTLHLRHANI---RESESTVRILADLQMNWIDKRLSWN 276
+D L+A Y R P VN+ L L A+I E+ + L +W D RLS+N
Sbjct: 44 LDGLIAGYARNFRPGIGGPPVNVALALEVASIDHISEANMEYTMTVFLHQSWRDSRLSYN 103
Query: 277 AGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTP 447
++LW PD ++NA + D + R+ +G + + R+ +
Sbjct: 104 HTNETLGLDSRFVDKLWLPDTFIVNAKSAWFHDVTVENKLIRLQPDGVILYSIRITSTVA 163
Query: 448 ISMQLDIWPNDMQTCTFKFGSRMHNSDEM 534
M L +P D Q C S ++S+++
Sbjct: 164 CDMDLAKYPMDEQECMLDLESYGYSSEDI 192
>AF009702-1|AAC24194.1| 440|Homo sapiens GABA-A receptor pi subunit
protein.
Length = 440
Score = 45.6 bits (103), Expect = 2e-04
Identities = 40/164 (24%), Positives = 78/164 (47%), Gaps = 9/164 (5%)
Frame = +1
Query: 76 ECENATSLSLM-IDSLLATYDRESPPD---SKIVVNLTLHLRH-ANIRESESTVRILADL 240
E + LSL ++L A Y++ P+ + + LTL + ++I ES L
Sbjct: 29 EVGRSDKLSLPGFENLTAGYNKFLRPNFGGEPVQIALTLDIASISSISESNMDYTATIYL 88
Query: 241 QMNWIDKRLSWNAGE-WGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNG 408
+ W+D+RL + + + LV E LW PD ++ + + + + R+ +NG
Sbjct: 89 RQRWMDQRLVFEGNKSFTLDARLV--EFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNG 146
Query: 409 SVSWIKRLDISTPISMQLDIWPNDMQTCTFKFGSRMHNSDEMDF 540
+V + R+ + +M L +P D QTC + S ++ ++++F
Sbjct: 147 TVLYALRITTTVACNMDLSKYPMDTQTCKLQLESWGYDGNDVEF 190
>S81944-1|AAB36480.1| 453|Homo sapiens gamma-aminobutyric acid type
A receptor alpha 6 subunit protein.
Length = 453
Score = 45.2 bits (102), Expect = 3e-04
Identities = 36/160 (22%), Positives = 66/160 (41%), Gaps = 7/160 (4%)
Frame = +1
Query: 94 SLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESESTVRILADLQMNWIDK 261
++S ++D+LL YD P + V +++ + + E + + W D+
Sbjct: 31 NVSRILDNLLEGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTDE 90
Query: 262 RLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRA---RVSNNGSVSWIKRL 432
RL + S + ++W PD N + A + R+ NG++ + RL
Sbjct: 91 RLKFGGPTEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTMRL 150
Query: 433 DISTPISMQLDIWPNDMQTCTFKFGSRMHNSDEMDFVIDK 552
I+ M+L +P D C KFGS + E+ + K
Sbjct: 151 TINADCPMRLVNFPMDGHACPLKFGSYAYPKSEIIYTWKK 190
>BC099641-1|AAH99641.1| 453|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 6 protein.
Length = 453
Score = 45.2 bits (102), Expect = 3e-04
Identities = 36/160 (22%), Positives = 66/160 (41%), Gaps = 7/160 (4%)
Frame = +1
Query: 94 SLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESESTVRILADLQMNWIDK 261
++S ++D+LL YD P + V +++ + + E + + W D+
Sbjct: 31 NVSRILDNLLEGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTDE 90
Query: 262 RLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRA---RVSNNGSVSWIKRL 432
RL + S + ++W PD N + A + R+ NG++ + RL
Sbjct: 91 RLKFGGPTEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTMRL 150
Query: 433 DISTPISMQLDIWPNDMQTCTFKFGSRMHNSDEMDFVIDK 552
I+ M+L +P D C KFGS + E+ + K
Sbjct: 151 TINADCPMRLVNFPMDGHACPLKFGSYAYPKSEIIYTWKK 190
>BC099640-1|AAH99640.1| 453|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 6 protein.
Length = 453
Score = 45.2 bits (102), Expect = 3e-04
Identities = 36/160 (22%), Positives = 66/160 (41%), Gaps = 7/160 (4%)
Frame = +1
Query: 94 SLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESESTVRILADLQMNWIDK 261
++S ++D+LL YD P + V +++ + + E + + W D+
Sbjct: 31 NVSRILDNLLEGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTDE 90
Query: 262 RLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRA---RVSNNGSVSWIKRL 432
RL + S + ++W PD N + A + R+ NG++ + RL
Sbjct: 91 RLKFGGPTEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTMRL 150
Query: 433 DISTPISMQLDIWPNDMQTCTFKFGSRMHNSDEMDFVIDK 552
I+ M+L +P D C KFGS + E+ + K
Sbjct: 151 TINADCPMRLVNFPMDGHACPLKFGSYAYPKSEIIYTWKK 190
>BC096242-1|AAH96242.1| 453|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 6 protein.
Length = 453
Score = 45.2 bits (102), Expect = 3e-04
Identities = 36/160 (22%), Positives = 66/160 (41%), Gaps = 7/160 (4%)
Frame = +1
Query: 94 SLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESESTVRILADLQMNWIDK 261
++S ++D+LL YD P + V +++ + + E + + W D+
Sbjct: 31 NVSRILDNLLEGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTDE 90
Query: 262 RLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRA---RVSNNGSVSWIKRL 432
RL + S + ++W PD N + A + R+ NG++ + RL
Sbjct: 91 RLKFGGPTEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTMRL 150
Query: 433 DISTPISMQLDIWPNDMQTCTFKFGSRMHNSDEMDFVIDK 552
I+ M+L +P D C KFGS + E+ + K
Sbjct: 151 TINADCPMRLVNFPMDGHACPLKFGSYAYPKSEIIYTWKK 190
>BC096241-1|AAH96241.1| 453|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 6 protein.
Length = 453
Score = 45.2 bits (102), Expect = 3e-04
Identities = 36/160 (22%), Positives = 66/160 (41%), Gaps = 7/160 (4%)
Frame = +1
Query: 94 SLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESESTVRILADLQMNWIDK 261
++S ++D+LL YD P + V +++ + + E + + W D+
Sbjct: 31 NVSRILDNLLEGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTDE 90
Query: 262 RLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRA---RVSNNGSVSWIKRL 432
RL + S + ++W PD N + A + R+ NG++ + RL
Sbjct: 91 RLKFGGPTEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTMRL 150
Query: 433 DISTPISMQLDIWPNDMQTCTFKFGSRMHNSDEMDFVIDK 552
I+ M+L +P D C KFGS + E+ + K
Sbjct: 151 TINADCPMRLVNFPMDGHACPLKFGSYAYPKSEIIYTWKK 190
>X52009-1|CAA36258.1| 449|Homo sapiens inhibitory glycine receptor
protein.
Length = 449
Score = 41.1 bits (92), Expect = 0.005
Identities = 29/119 (24%), Positives = 53/119 (44%), Gaps = 4/119 (3%)
Frame = +1
Query: 196 NIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERLWRPDVVLLNAAATTAG 372
+I E+ R+ L+ W D RL++N S + +W+PD+ N
Sbjct: 78 SIAETTMDYRVNIFLRQQWNDPRLAYNEYPDDSLDLDPSMLDSIWKPDLFFANEKGAHFH 137
Query: 373 DYALR---ARVSNNGSVSWIKRLDISTPISMQLDIWPNDMQTCTFKFGSRMHNSDEMDF 540
+ R+S NG+V + R+ ++ M L +P D+QTC + S + +++ F
Sbjct: 138 EITTDNKLLRISRNGNVLYSIRITLTLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIF 196
>BC114947-1|AAI14948.1| 457|Homo sapiens GLRA1 protein protein.
Length = 457
Score = 41.1 bits (92), Expect = 0.005
Identities = 29/119 (24%), Positives = 53/119 (44%), Gaps = 4/119 (3%)
Frame = +1
Query: 196 NIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERLWRPDVVLLNAAATTAG 372
+I E+ R+ L+ W D RL++N S + +W+PD+ N
Sbjct: 78 SIAETTMDYRVNIFLRQQWNDPRLAYNEYPDDSLDLDPSMLDSIWKPDLFFANEKGAHFH 137
Query: 373 DYALR---ARVSNNGSVSWIKRLDISTPISMQLDIWPNDMQTCTFKFGSRMHNSDEMDF 540
+ R+S NG+V + R+ ++ M L +P D+QTC + S + +++ F
Sbjct: 138 EITTDNKLLRISRNGNVLYSIRITLTLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIF 196
>BC074980-1|AAH74980.1| 449|Homo sapiens glycine receptor, alpha 1
(startle disease/hyperekplexia) protein.
Length = 449
Score = 41.1 bits (92), Expect = 0.005
Identities = 29/119 (24%), Positives = 53/119 (44%), Gaps = 4/119 (3%)
Frame = +1
Query: 196 NIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERLWRPDVVLLNAAATTAG 372
+I E+ R+ L+ W D RL++N S + +W+PD+ N
Sbjct: 78 SIAETTMDYRVNIFLRQQWNDPRLAYNEYPDDSLDLDPSMLDSIWKPDLFFANEKGAHFH 137
Query: 373 DYALR---ARVSNNGSVSWIKRLDISTPISMQLDIWPNDMQTCTFKFGSRMHNSDEMDF 540
+ R+S NG+V + R+ ++ M L +P D+QTC + S + +++ F
Sbjct: 138 EITTDNKLLRISRNGNVLYSIRITLTLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIF 196
>Z93848-1|CAI41994.1| 376|Homo sapiens glycine receptor, alpha 4
protein.
Length = 376
Score = 39.9 bits (89), Expect = 0.012
Identities = 36/145 (24%), Positives = 62/145 (42%), Gaps = 8/145 (5%)
Frame = +1
Query: 130 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 297
YD P+ K VN+T ++ ++I ++ R+ L+ W D RLS+
Sbjct: 17 YDARIRPNFKGPPVNVTCNIFINSFSSITKTTMDYRVNVFLRQQWNDPRLSYREYPDDSL 76
Query: 298 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLD 465
S + +W+PD+ N + R+ NG+V + RL + M L
Sbjct: 77 DLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLILSCLMDLK 136
Query: 466 IWPNDMQTCTFKFGSRMHNSDEMDF 540
+P D+QTCT + S + ++ F
Sbjct: 137 NFPMDIQTCTMQLESFGYTMKDLVF 161
>U93917-1|AAC39917.1| 449|Homo sapiens glycine receptor alpha 3
subunit protein.
Length = 449
Score = 39.9 bits (89), Expect = 0.012
Identities = 35/145 (24%), Positives = 63/145 (43%), Gaps = 8/145 (5%)
Frame = +1
Query: 130 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 297
YD P+ K VN+T ++ +I E+ R+ L+ W D RL+++
Sbjct: 57 YDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPDDSL 116
Query: 298 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLD 465
S + +W+PD+ N + R+ NG+V + RL ++ M L
Sbjct: 117 DLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLK 176
Query: 466 IWPNDMQTCTFKFGSRMHNSDEMDF 540
+P D+QTC + S + +++ F
Sbjct: 177 NFPMDVQTCIMQLESFGYTMNDLIF 201
>BC036086-1|AAH36086.1| 464|Homo sapiens glycine receptor, alpha 3
protein.
Length = 464
Score = 39.9 bits (89), Expect = 0.012
Identities = 35/145 (24%), Positives = 63/145 (43%), Gaps = 8/145 (5%)
Frame = +1
Query: 130 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 297
YD P+ K VN+T ++ +I E+ R+ L+ W D RL+++
Sbjct: 57 YDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPDDSL 116
Query: 298 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLD 465
S + +W+PD+ N + R+ NG+V + RL ++ M L
Sbjct: 117 DLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLK 176
Query: 466 IWPNDMQTCTFKFGSRMHNSDEMDF 540
+P D+QTC + S + +++ F
Sbjct: 177 NFPMDVQTCIMQLESFGYTMNDLIF 201
>AL049610-1|CAI42158.1| 376|Homo sapiens glycine receptor, alpha 4
protein.
Length = 376
Score = 39.9 bits (89), Expect = 0.012
Identities = 36/145 (24%), Positives = 62/145 (42%), Gaps = 8/145 (5%)
Frame = +1
Query: 130 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 297
YD P+ K VN+T ++ ++I ++ R+ L+ W D RLS+
Sbjct: 17 YDARIRPNFKGPPVNVTCNIFINSFSSITKTTMDYRVNVFLRQQWNDPRLSYREYPDDSL 76
Query: 298 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLD 465
S + +W+PD+ N + R+ NG+V + RL + M L
Sbjct: 77 DLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLILSCLMDLK 136
Query: 466 IWPNDMQTCTFKFGSRMHNSDEMDF 540
+P D+QTCT + S + ++ F
Sbjct: 137 NFPMDIQTCTMQLESFGYTMKDLVF 161
>AF017724-1|AAC39919.1| 465|Homo sapiens glycine receptor alpha 3
subunit protein.
Length = 465
Score = 39.9 bits (89), Expect = 0.012
Identities = 35/145 (24%), Positives = 63/145 (43%), Gaps = 8/145 (5%)
Frame = +1
Query: 130 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 297
YD P+ K VN+T ++ +I E+ R+ L+ W D RL+++
Sbjct: 57 YDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPDDSL 116
Query: 298 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLD 465
S + +W+PD+ N + R+ NG+V + RL ++ M L
Sbjct: 117 DLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLK 176
Query: 466 IWPNDMQTCTFKFGSRMHNSDEMDF 540
+P D+QTC + S + +++ F
Sbjct: 177 NFPMDVQTCIMQLESFGYTMNDLIF 201
>AB209359-1|BAD92596.1| 533|Homo sapiens cholinergic receptor,
nicotinic, alpha polypeptide 4 precursor variant
protein.
Length = 533
Score = 39.1 bits (87), Expect = 0.021
Identities = 20/74 (27%), Positives = 34/74 (45%)
Frame = +1
Query: 322 LWRPDVVLLNAAATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDIWPNDMQTCTFK 501
LW +A A + +A + ++G V W + S+ + +P D Q CT K
Sbjct: 25 LWLCCCTFTSADGDFAVTHLTKAHLFHDGRVQWTPPAIYKSSCSIDVTFFPFDQQNCTMK 84
Query: 502 FGSRMHNSDEMDFV 543
FGS ++ ++D V
Sbjct: 85 FGSWTYDKAKIDLV 98
>BC114967-1|AAI14968.1| 366|Homo sapiens GLRA1 protein protein.
Length = 366
Score = 38.7 bits (86), Expect = 0.028
Identities = 27/110 (24%), Positives = 49/110 (44%), Gaps = 4/110 (3%)
Frame = +1
Query: 223 RILADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERLWRPDVVLLNAAATTAGDYALR---A 390
R+ L+ W D RL++N S + +W+PD+ N +
Sbjct: 4 RVNIFLRQQWNDPRLAYNEYPDDSLDLDPSMLDSIWKPDLFFANEKGAHFHEITTDNKLL 63
Query: 391 RVSNNGSVSWIKRLDISTPISMQLDIWPNDMQTCTFKFGSRMHNSDEMDF 540
R+S NG+V + R+ ++ M L +P D+QTC + S + +++ F
Sbjct: 64 RISRNGNVLYSIRITLTLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIF 113
>BC096291-1|AAH96291.1| 556|Homo sapiens CHRNA4 protein protein.
Length = 556
Score = 38.3 bits (85), Expect = 0.038
Identities = 19/62 (30%), Positives = 33/62 (53%), Gaps = 4/62 (6%)
Frame = +1
Query: 370 GDYAL----RARVSNNGSVSWIKRLDISTPISMQLDIWPNDMQTCTFKFGSRMHNSDEMD 537
GD+A+ +A + ++G V W + S+ + +P D Q CT KFGS ++ ++D
Sbjct: 60 GDFAVTHLTKAHLFHDGRVQWTPPAIYKSSCSIDVTFFPFDQQNCTMKFGSWTYDKAKID 119
Query: 538 FV 543
V
Sbjct: 120 LV 121
>BC146774-1|AAI46775.1| 1114|Homo sapiens GPR124 protein protein.
Length = 1114
Score = 30.7 bits (66), Expect = 7.5
Identities = 16/55 (29%), Positives = 26/55 (47%), Gaps = 1/55 (1%)
Frame = +1
Query: 271 WNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNN-GSVSWIKRL 432
W +GEW C+ + + ++V+L T+ Y RV+NN G W + L
Sbjct: 314 WASGEWECTVSMAQGNASKKVEIVVLE----TSASYCPAERVANNRGDFRWPRTL 364
>AY181242-1|AAO27354.1| 1331|Homo sapiens G protein-coupled receptor
124 protein.
Length = 1331
Score = 30.7 bits (66), Expect = 7.5
Identities = 16/55 (29%), Positives = 26/55 (47%), Gaps = 1/55 (1%)
Frame = +1
Query: 271 WNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNN-GSVSWIKRL 432
W +GEW C+ + + ++V+L T+ Y RV+NN G W + L
Sbjct: 314 WASGEWECTVSMAQGNASKKVEIVVLE----TSASYCPAERVANNRGDFRWPRTL 364
>AK074099-1|BAB84925.1| 1310|Homo sapiens FLJ00170 protein protein.
Length = 1310
Score = 30.7 bits (66), Expect = 7.5
Identities = 16/55 (29%), Positives = 26/55 (47%), Gaps = 1/55 (1%)
Frame = +1
Query: 271 WNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNN-GSVSWIKRL 432
W +GEW C+ + + ++V+L T+ Y RV+NN G W + L
Sbjct: 293 WASGEWECTVSMAQGNASKKVEIVVLE----TSASYCPAERVANNRGDFRWPRTL 343
>AF378755-1|AAL11992.1| 1331|Homo sapiens tumor endothelial marker 5
precursor protein.
Length = 1331
Score = 30.7 bits (66), Expect = 7.5
Identities = 16/55 (29%), Positives = 26/55 (47%), Gaps = 1/55 (1%)
Frame = +1
Query: 271 WNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNN-GSVSWIKRL 432
W +GEW C+ + + ++V+L T+ Y RV+NN G W + L
Sbjct: 314 WASGEWECTVSMAQGNASKKVEIVVLE----TSASYCPAERVANNRGDFRWPRTL 364
>AB040964-1|BAA96055.2| 1206|Homo sapiens KIAA1531 protein protein.
Length = 1206
Score = 30.7 bits (66), Expect = 7.5
Identities = 16/55 (29%), Positives = 26/55 (47%), Gaps = 1/55 (1%)
Frame = +1
Query: 271 WNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNN-GSVSWIKRL 432
W +GEW C+ + + ++V+L T+ Y RV+NN G W + L
Sbjct: 406 WASGEWECTVSMAQGNASKKVEIVVLE----TSASYCPAERVANNRGDFRWPRTL 456
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 103,781,414
Number of Sequences: 237096
Number of extensions: 2271194
Number of successful extensions: 5737
Number of sequences better than 10.0: 165
Number of HSP's better than 10.0 without gapping: 5358
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5594
length of database: 76,859,062
effective HSP length: 90
effective length of database: 55,520,422
effective search space used: 11603768198
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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