Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BmNP06_FL5_N12
(877 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
AJ306454-1|CAC34819.1| 497|Homo sapiens neuronal nicotinic acet... 69 2e-11
Y08416-1|CAA69693.1| 498|Homo sapiens nicotinic acetylcholine r... 67 7e-11
U62439-1|AAB40117.1| 498|Homo sapiens nicotinic acetylcholine r... 67 7e-11
U48861-1|AAA92123.1| 498|Homo sapiens beta 4 nicotinic acetylch... 67 7e-11
BC096082-1|AAH96082.1| 498|Homo sapiens cholinergic receptor, n... 67 7e-11
BC096080-1|AAH96080.1| 498|Homo sapiens cholinergic receptor, n... 67 7e-11
AF306329-1|AAL02062.1| 498|Homo sapiens neuronal nicotinic acet... 67 7e-11
Y08417-1|CAA69694.1| 458|Homo sapiens nicotinic acetylcholine r... 65 3e-10
X67513-1|CAA47851.1| 423|Homo sapiens nicotinic acetylcholine ... 65 3e-10
U62438-1|AAB40116.1| 458|Homo sapiens nicotinic acetylcholine r... 65 3e-10
BC069788-1|AAH69788.1| 458|Homo sapiens cholinergic receptor, n... 65 3e-10
BC069703-1|AAH69703.1| 458|Homo sapiens cholinergic receptor, n... 65 3e-10
BC069681-1|AAH69681.1| 458|Homo sapiens cholinergic receptor, n... 65 3e-10
AF140765-1|AAD33063.1| 458|Homo sapiens neuronal acetylcholine ... 65 3e-10
BT006897-1|AAP35543.1| 505|Homo sapiens cholinergic receptor, n... 64 5e-10
BT006646-1|AAP35292.1| 489|Homo sapiens cholinergic receptor, n... 64 5e-10
BC006114-1|AAH06114.1| 489|Homo sapiens CHRNA3 protein protein. 64 5e-10
BC002996-1|AAH02996.1| 505|Homo sapiens cholinergic receptor, n... 64 5e-10
BC001642-1|AAH01642.1| 505|Homo sapiens cholinergic receptor, n... 64 5e-10
BC000513-1|AAH00513.1| 505|Homo sapiens cholinergic receptor, n... 64 5e-10
AF385584-1|AAK68110.1| 489|Homo sapiens nicotinic cholinergic r... 64 5e-10
Y08419-1|CAA69696.1| 468|Homo sapiens nicotinic acetylcholine r... 64 8e-10
Y08418-1|CAA69695.1| 503|Homo sapiens nicotinic acetylcholine r... 64 8e-10
U62434-1|AAB40112.1| 468|Homo sapiens nicotinic acetylcholine r... 64 8e-10
U62432-1|AAB40110.1| 504|Homo sapiens nicotinic acetylcholine r... 64 8e-10
M37981-1|AAA59942.1| 503|Homo sapiens neuronal nicotinic acetyl... 64 8e-10
BC098443-1|AAH98443.1| 504|Homo sapiens cholinergic receptor, n... 64 8e-10
BC033639-1|AAH33639.1| 468|Homo sapiens cholinergic receptor, n... 64 8e-10
AJ306481-1|CAC34820.1| 468|Homo sapiens neuronal nicotinic acet... 64 8e-10
AJ007783-1|CAA07682.1| 504|Homo sapiens nicotinic acetylcholine... 64 8e-10
X68275-1|CAA48336.1| 451|Homo sapiens nicotinic receptor beta 4... 63 1e-09
X53559-1|CAA37625.1| 474|Homo sapiens neuronal nicotinic acetyl... 63 1e-09
M83712-1|AAA58357.1| 468|Homo sapiens nicotinic receptor alpha ... 62 2e-09
X14830-1|CAA32939.1| 501|Homo sapiens protein ( Human mRNA for ... 61 4e-09
M86383-1|AAC84176.1| 502|Homo sapiens nicotinic acetylcholine r... 61 4e-09
BC011371-1|AAH11371.1| 501|Homo sapiens cholinergic receptor, n... 61 4e-09
Y16282-1|CAA76155.1| 494|Homo sapiens nicotinic acetylcholine r... 61 6e-09
Y16281-1|CAA76154.1| 529|Homo sapiens nicotinic acetylcholine r... 61 6e-09
U62435-1|AAB40113.1| 494|Homo sapiens nicotinic acetylcholine r... 61 6e-09
U62431-1|AAB40109.1| 529|Homo sapiens nicotinic acetylcholine r... 61 6e-09
BC014456-1|AAH14456.1| 494|Homo sapiens cholinergic receptor, n... 61 6e-09
AB079251-1|BAC06855.1| 494|Homo sapiens Nicotinic acetylcholine... 61 6e-09
DQ644022-1|ABG35128.1| 456|Homo sapiens 5-HT3 receptor subunit ... 60 8e-09
Y08421-1|CAA69698.1| 627|Homo sapiens nicotinic acetylcholine r... 60 1e-08
X89741-1|CAA61893.1| 627|Homo sapiens neuronal acetylcholine re... 60 1e-08
U62433-1|AAB40111.1| 627|Homo sapiens nicotinic acetylcholine r... 60 1e-08
L35901-1|AAA64743.1| 627|Homo sapiens nicotinic acetylcholine r... 60 1e-08
DQ093071-1|AAY88737.1| 627|Homo sapiens cholinergic receptor, n... 60 1e-08
BC101185-1|AAI01186.1| 374|Homo sapiens HTR3E protein protein. 60 1e-08
BC101183-1|AAI01184.1| 471|Homo sapiens 5-hydroxytryptamine (se... 60 1e-08
BC101182-1|AAI01183.1| 471|Homo sapiens 5-hydroxytryptamine (se... 60 1e-08
BC096290-1|AAH96290.1| 627|Homo sapiens cholinergic receptor, n... 60 1e-08
BC023553-1|AAH23553.1| 501|Homo sapiens cholinergic receptor, n... 60 1e-08
AY159813-1|AAO38167.2| 471|Homo sapiens 5-hydroxytryptamine ser... 60 1e-08
X87629-1|CAA60959.1| 602|Homo sapiens nicotinic acetylcholine r... 60 1e-08
X01715-1|CAA25861.1| 520|Homo sapiens acetylcholine receptor ga... 60 1e-08
AC092165-3|AAY24103.1| 520|Homo sapiens unknown protein. 60 1e-08
X66403-1|CAA47030.1| 493|Homo sapiens acetylcholine receptor ep... 59 2e-08
AF105999-1|AAD24503.1| 493|Homo sapiens acetylcholine receptor ... 59 2e-08
BC131799-1|AAI31800.1| 447|Homo sapiens 5-hydroxytryptamine (se... 59 2e-08
Y00762-1|CAA68731.1| 457|Homo sapiens protein ( Human mRNA for ... 58 3e-08
X02502-1|CAA26344.1| 457|Homo sapiens acetylcholine receptor pr... 58 3e-08
S77094-1|AAD14247.1| 457|Homo sapiens nicotinic acetylcholine r... 58 3e-08
BC006314-1|AAH06314.1| 269|Homo sapiens CHRNA1 protein protein. 58 3e-08
AF459285-1|AAL66182.1| 447|Homo sapiens 5-hydroxytryptamine rec... 58 3e-08
AC018890-1|AAY14687.1| 457|Homo sapiens unknown protein. 58 3e-08
AY349353-1|AAQ93477.1| 456|Homo sapiens 5-HT3c1 serotonin recep... 58 4e-08
AY349352-1|AAQ93476.1| 441|Homo sapiens 5-HT3c1 serotonin recep... 58 4e-08
AJ295237-1|CAC16144.1| 450|Homo sapiens neuronal nicotinic acet... 58 6e-08
AJ278118-1|CAC20435.1| 450|Homo sapiens neuronal nicotinic acet... 58 6e-08
AF327367-1|AAK14333.1| 450|Homo sapiens nicotinic acetylcholine... 58 6e-08
AF199235-1|AAG00795.2| 450|Homo sapiens nicotinic acetylcholine... 58 6e-08
BC113575-1|AAI13576.1| 479|Homo sapiens cholinergic receptor, n... 57 7e-08
BC113549-1|AAI13550.1| 479|Homo sapiens cholinergic receptor, n... 57 7e-08
AY123244-1|AAM74523.1| 479|Homo sapiens nicotinic acetylcholine... 57 7e-08
AJ243342-1|CAB65091.1| 479|Homo sapiens nicotinic acetylcholine... 57 7e-08
AF227732-1|AAF61920.1| 470|Homo sapiens nicotinic acetylcholine... 57 7e-08
AC118275-1|AAY40986.1| 479|Homo sapiens unknown protein. 57 7e-08
AJ001935-1|CAA05108.1| 504|Homo sapiens CHRNB2 protein. 56 2e-07
Y08415-1|CAA69692.1| 502|Homo sapiens nicotinic acetylcholine r... 56 2e-07
X53179-1|CAA37320.1| 502|Homo sapiens precursor peptide (AA -25... 56 2e-07
U62437-1|AAB40115.1| 502|Homo sapiens nicotinic acetylcholine r... 56 2e-07
BC075041-1|AAH75041.1| 502|Homo sapiens cholinergic receptor, n... 56 2e-07
BC075040-1|AAH75040.1| 502|Homo sapiens cholinergic receptor, n... 56 2e-07
AL592078-3|CAI16184.1| 502|Homo sapiens cholinergic receptor, n... 56 2e-07
AF077186-1|AAD45422.1| 502|Homo sapiens neuronal nicotinic acet... 56 2e-07
BC111802-1|AAI11803.1| 465|Homo sapiens CHRNG protein protein. 53 1e-06
X55019-1|CAA38759.1| 517|Homo sapiens acetylcholine receptor de... 52 3e-06
BC093925-1|AAH93925.1| 517|Homo sapiens cholinergic receptor, n... 52 3e-06
BC093923-1|AAH93923.1| 517|Homo sapiens cholinergic receptor, n... 52 3e-06
AC092165-2|AAY24102.1| 517|Homo sapiens unknown protein. 52 3e-06
S77554-1|AAB33983.1| 474|Homo sapiens GABAA receptor beta 2 sub... 52 4e-06
S77553-1|AAB33982.1| 512|Homo sapiens GABAA receptor beta 2 sub... 52 4e-06
S67368-1|AAB29370.1| 474|Homo sapiens gamma-aminobutyric acid A... 52 4e-06
BC105639-1|AAI05640.1| 474|Homo sapiens GABRB2 protein protein. 52 4e-06
BC099719-1|AAH99719.1| 474|Homo sapiens GABRB2 protein protein. 52 4e-06
BC099705-1|AAH99705.1| 474|Homo sapiens GABRB2 protein protein. 52 4e-06
S82612-1|AAB37533.2| 478|Homo sapiens 5-hydroxytryptamine type ... 51 5e-06
M59216-1|AAA35862.1| 474|Homo sapiens gamma-aminobutyric acid r... 51 5e-06
BC110597-1|AAI10598.1| 411|Homo sapiens ligand-gated ion channe... 51 6e-06
AF512521-1|AAO20969.1| 411|Homo sapiens ligand-gated ion channe... 51 6e-06
X14767-1|CAA32875.1| 474|Homo sapiens GABA-A receptor beta 1 su... 50 8e-06
D49394-1|BAA08387.1| 478|Homo sapiens serotonin 5-HT3 receptor ... 50 8e-06
BT007204-1|AAP35868.1| 484|Homo sapiens 5-hydroxytryptamine (se... 50 8e-06
BC004453-1|AAH04453.2| 478|Homo sapiens 5-hydroxytryptamine (se... 50 8e-06
BC002354-1|AAH02354.1| 478|Homo sapiens 5-hydroxytryptamine (se... 50 8e-06
AJ005205-1|CAA06442.3| 478|Homo sapiens serotonin 3 receptor pr... 50 8e-06
AJ003079-1|CAA05852.1| 478|Homo sapiens 5-hydroxytryptamine3 re... 50 8e-06
AJ003078-1|CAA05851.1| 510|Homo sapiens serotonin receptor prot... 50 8e-06
AF498984-1|AAM21131.1| 478|Homo sapiens 5-hydroxytryptamine rec... 50 8e-06
AB223030-1|BAE19924.1| 411|Homo sapiens ligand-gated ion-channe... 50 8e-06
AK122638-1|BAC85499.1| 266|Homo sapiens yte protein of 76kDa) (... 50 1e-05
Z23141-1|CAA80672.1| 479|Homo sapiens cholinergic receptor, nic... 49 3e-05
Y08420-1|CAA69697.1| 502|Homo sapiens nicotinic acetylcholine r... 49 3e-05
X70297-1|CAA49778.1| 502|Homo sapiens neuronal nicotinic acetyl... 49 3e-05
U62436-1|AAB40114.1| 502|Homo sapiens nicotinic acetylcholine r... 49 3e-05
AJ586911-1|CAE52911.1| 502|Homo sapiens nicotinic acetylcholine... 49 3e-05
U40583-1|AAA83561.1| 502|Homo sapiens alpha 7 neuronal nicotini... 48 6e-05
AF385585-1|AAK68111.1| 502|Homo sapiens nicotinic cholinergic r... 48 6e-05
L08485-1|AAA58490.1| 462|Homo sapiens GABA-benzodiazepine recep... 47 8e-05
BT009830-1|AAP88832.1| 462|Homo sapiens gamma-aminobutyric acid... 47 8e-05
BC113422-1|AAI13423.1| 462|Homo sapiens gamma-aminobutyric acid... 47 8e-05
BC111979-1|AAI11980.1| 462|Homo sapiens gamma-aminobutyric acid... 47 8e-05
BC109211-1|AAI09212.1| 632|Homo sapiens gamma-aminobutyric acid... 47 1e-04
BC109210-1|AAI09211.1| 632|Homo sapiens gamma-aminobutyric acid... 47 1e-04
BC096083-1|AAH96083.1| 198|Homo sapiens CHRNB4 protein protein. 47 1e-04
BC096081-1|AAH96081.1| 198|Homo sapiens CHRNB4 protein protein. 47 1e-04
AF189259-1|AAF70380.1| 632|Homo sapiens GABA-A receptor theta s... 47 1e-04
AF144648-1|AAD51172.1| 627|Homo sapiens GABA-A receptor theta p... 47 1e-04
U77731-2|AAB38273.1| 360|Homo sapiens glycine receptor alpha 2B... 46 1e-04
CR450343-1|CAG29339.1| 452|Homo sapiens GLRA2 protein. 46 1e-04
AY437084-1|AAR87843.1| 452|Homo sapiens glycine receptor alpha2... 46 1e-04
X52008-1|CAA36257.1| 452|Homo sapiens inhibitory glycine recept... 46 2e-04
U77731-1|AAB38272.1| 360|Homo sapiens glycine receptor alpha 2 ... 46 2e-04
BC032864-1|AAH32864.1| 452|Homo sapiens glycine receptor, alpha... 46 2e-04
BC028629-1|AAH28629.1| 492|Homo sapiens gamma-aminobutyric acid... 46 2e-04
BC022449-1|AAH22449.1| 474|Homo sapiens gamma-aminobutyric acid... 46 2e-04
AY437083-1|AAR87842.1| 452|Homo sapiens glycine receptor alpha2... 46 2e-04
AF053495-1|AAC35290.1| 452|Homo sapiens glycine receptor alpha ... 46 2e-04
S62908-1|AAB27279.1| 492|Homo sapiens gamma-aminobutyric acidA ... 46 2e-04
AF166361-1|AAG12455.1| 492|Homo sapiens GABA receptor subunit a... 46 2e-04
BC033801-1|AAH33801.1| 452|Homo sapiens gamma-aminobutyric acid... 44 0.001
AL391845-4|CAI15436.1| 452|Homo sapiens gamma-aminobutyric acid... 44 0.001
AF016917-1|AAB70007.1| 452|Homo sapiens GABA-A receptor delta s... 44 0.001
U95367-1|AAC51357.1| 440|Homo sapiens GABA-A receptor pi subuni... 43 0.001
BC109106-1|AAI09107.1| 440|Homo sapiens gamma-aminobutyric acid... 43 0.001
BC109105-1|AAI09106.1| 440|Homo sapiens gamma-aminobutyric acid... 43 0.001
BC074865-1|AAH74865.1| 440|Homo sapiens gamma-aminobutyric acid... 43 0.001
BC074810-1|AAH74810.1| 440|Homo sapiens gamma-aminobutyric acid... 43 0.001
AF009702-1|AAC24194.1| 440|Homo sapiens GABA-A receptor pi subu... 43 0.001
U93917-1|AAC39917.1| 449|Homo sapiens glycine receptor alpha 3 ... 42 0.002
BC114947-1|AAI14948.1| 457|Homo sapiens GLRA1 protein protein. 42 0.002
BC074980-1|AAH74980.1| 449|Homo sapiens glycine receptor, alpha... 42 0.002
BC036086-1|AAH36086.1| 464|Homo sapiens glycine receptor, alpha... 42 0.002
AF017724-1|AAC39919.1| 465|Homo sapiens glycine receptor alpha ... 42 0.002
X52009-1|CAA36258.1| 449|Homo sapiens inhibitory glycine recept... 42 0.003
U30461-1|AAB52519.1| 554|Homo sapiens GABAA receptor subunit al... 42 0.004
S81944-1|AAB36480.1| 453|Homo sapiens gamma-aminobutyric acid t... 42 0.004
BC099641-1|AAH99641.1| 453|Homo sapiens gamma-aminobutyric acid... 42 0.004
BC099640-1|AAH99640.1| 453|Homo sapiens gamma-aminobutyric acid... 42 0.004
BC096242-1|AAH96242.1| 453|Homo sapiens gamma-aminobutyric acid... 42 0.004
BC096241-1|AAH96241.1| 453|Homo sapiens gamma-aminobutyric acid... 42 0.004
BC035055-1|AAH35055.1| 554|Homo sapiens gamma-aminobutyric acid... 42 0.004
Z93848-1|CAI41994.1| 376|Homo sapiens glycine receptor, alpha 4... 40 0.012
AL049610-1|CAI42158.1| 376|Homo sapiens glycine receptor, alpha... 40 0.012
BC114967-1|AAI14968.1| 366|Homo sapiens GLRA1 protein protein. 39 0.027
AB209359-1|BAD92596.1| 533|Homo sapiens cholinergic receptor, n... 35 0.44
BC096291-1|AAH96291.1| 556|Homo sapiens CHRNA4 protein protein. 34 0.78
BC146774-1|AAI46775.1| 1114|Homo sapiens GPR124 protein protein. 31 7.2
AY181242-1|AAO27354.1| 1331|Homo sapiens G protein-coupled recep... 31 7.2
AK074099-1|BAB84925.1| 1310|Homo sapiens FLJ00170 protein protein. 31 7.2
AF378755-1|AAL11992.1| 1331|Homo sapiens tumor endothelial marke... 31 7.2
AB040964-1|BAA96055.2| 1206|Homo sapiens KIAA1531 protein protein. 31 7.2
>AJ306454-1|CAC34819.1| 497|Homo sapiens neuronal nicotinic
acetylcholine receptor beta-4 subunit protein.
Length = 497
Score = 69.3 bits (162), Expect = 2e-11
Identities = 48/179 (26%), Positives = 82/179 (45%), Gaps = 8/179 (4%)
Frame = +1
Query: 67 LLPFLLTCAIASAAECENATSLSLMIDSLL--ATYDRESPP--DSKIVVNLTLHLRHA-- 228
L+ F L A+ C A + ++D LL Y+ P S ++++ L L A
Sbjct: 7 LVLFFLV-ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQL 65
Query: 229 -NIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTA 402
++ E E + L+ W D RL+WN+ + G + + ++R+W PD+VL N T
Sbjct: 66 ISVNEREQIMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNDGTYE 125
Query: 403 GDYALRARVSNNGSVSWIKRLDISTPISMQLDXWPNDMQTCTFGFGSXMHNIDXMDFVI 579
V +NGSV W+ + +++ +P D Q CT F S ++ +D V+
Sbjct: 126 VSVYTNLIVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRSWTYDHTEIDMVL 184
>Y08416-1|CAA69693.1| 498|Homo sapiens nicotinic acetylcholine
receptor beta4 subunit precursor protein.
Length = 498
Score = 67.3 bits (157), Expect = 7e-11
Identities = 49/180 (27%), Positives = 83/180 (46%), Gaps = 9/180 (5%)
Frame = +1
Query: 67 LLPFLLTCAIASAAECENATSLSLMIDSLL--ATYDRESPP--DSKIVVNLTLHLRHA-- 228
L+ F L A+ C A + ++D LL Y+ P S ++++ L L A
Sbjct: 7 LVLFFLV-ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQL 65
Query: 229 -NIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATT 399
++ E E + L+ W D RL+WN+ + G + + ++R+W PD+VL N A T
Sbjct: 66 ISVNEREQIMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNADGTY 125
Query: 400 AGDYALRARVSNNGSVSWIKRLDISTPISMQLDXWPNDMQTCTFGFGSXMHNIDXMDFVI 579
V +NGSV W+ + +++ +P D Q CT F S ++ +D V+
Sbjct: 126 EVSVYTNLIVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRSWTYDHTEIDMVL 185
>U62439-1|AAB40117.1| 498|Homo sapiens nicotinic acetylcholine
receptor beta4 subunit precursor protein.
Length = 498
Score = 67.3 bits (157), Expect = 7e-11
Identities = 49/180 (27%), Positives = 83/180 (46%), Gaps = 9/180 (5%)
Frame = +1
Query: 67 LLPFLLTCAIASAAECENATSLSLMIDSLL--ATYDRESPP--DSKIVVNLTLHLRHA-- 228
L+ F L A+ C A + ++D LL Y+ P S ++++ L L A
Sbjct: 7 LVLFFLV-ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQL 65
Query: 229 -NIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATT 399
++ E E + L+ W D RL+WN+ + G + + ++R+W PD+VL N A T
Sbjct: 66 ISVNEREQIMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNADGTY 125
Query: 400 AGDYALRARVSNNGSVSWIKRLDISTPISMQLDXWPNDMQTCTFGFGSXMHNIDXMDFVI 579
V +NGSV W+ + +++ +P D Q CT F S ++ +D V+
Sbjct: 126 EVSVYTNLIVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRSWTYDHTEIDMVL 185
>U48861-1|AAA92123.1| 498|Homo sapiens beta 4 nicotinic
acetylcholine receptor subunit protein.
Length = 498
Score = 67.3 bits (157), Expect = 7e-11
Identities = 49/180 (27%), Positives = 83/180 (46%), Gaps = 9/180 (5%)
Frame = +1
Query: 67 LLPFLLTCAIASAAECENATSLSLMIDSLL--ATYDRESPP--DSKIVVNLTLHLRHA-- 228
L+ F L A+ C A + ++D LL Y+ P S ++++ L L A
Sbjct: 7 LVLFFLV-ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQL 65
Query: 229 -NIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATT 399
++ E E + L+ W D RL+WN+ + G + + ++R+W PD+VL N A T
Sbjct: 66 ISVNEREQIMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNADGTY 125
Query: 400 AGDYALRARVSNNGSVSWIKRLDISTPISMQLDXWPNDMQTCTFGFGSXMHNIDXMDFVI 579
V +NGSV W+ + +++ +P D Q CT F S ++ +D V+
Sbjct: 126 EVSVYTNLIVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRSWTYDHTEIDMVL 185
>BC096082-1|AAH96082.1| 498|Homo sapiens cholinergic receptor,
nicotinic, beta 4 protein.
Length = 498
Score = 67.3 bits (157), Expect = 7e-11
Identities = 49/180 (27%), Positives = 83/180 (46%), Gaps = 9/180 (5%)
Frame = +1
Query: 67 LLPFLLTCAIASAAECENATSLSLMIDSLL--ATYDRESPP--DSKIVVNLTLHLRHA-- 228
L+ F L A+ C A + ++D LL Y+ P S ++++ L L A
Sbjct: 7 LVLFFLV-ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQL 65
Query: 229 -NIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATT 399
++ E E + L+ W D RL+WN+ + G + + ++R+W PD+VL N A T
Sbjct: 66 ISVNEREQIMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNADGTY 125
Query: 400 AGDYALRARVSNNGSVSWIKRLDISTPISMQLDXWPNDMQTCTFGFGSXMHNIDXMDFVI 579
V +NGSV W+ + +++ +P D Q CT F S ++ +D V+
Sbjct: 126 EVSVYTNLIVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRSWTYDHTEIDMVL 185
>BC096080-1|AAH96080.1| 498|Homo sapiens cholinergic receptor,
nicotinic, beta 4 protein.
Length = 498
Score = 67.3 bits (157), Expect = 7e-11
Identities = 49/180 (27%), Positives = 83/180 (46%), Gaps = 9/180 (5%)
Frame = +1
Query: 67 LLPFLLTCAIASAAECENATSLSLMIDSLL--ATYDRESPP--DSKIVVNLTLHLRHA-- 228
L+ F L A+ C A + ++D LL Y+ P S ++++ L L A
Sbjct: 7 LVLFFLV-ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQL 65
Query: 229 -NIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATT 399
++ E E + L+ W D RL+WN+ + G + + ++R+W PD+VL N A T
Sbjct: 66 ISVNEREQIMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNADGTY 125
Query: 400 AGDYALRARVSNNGSVSWIKRLDISTPISMQLDXWPNDMQTCTFGFGSXMHNIDXMDFVI 579
V +NGSV W+ + +++ +P D Q CT F S ++ +D V+
Sbjct: 126 EVSVYTNLIVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRSWTYDHTEIDMVL 185
>AF306329-1|AAL02062.1| 498|Homo sapiens neuronal nicotinic
acetylcholine receptor beta 4 subunit protein.
Length = 498
Score = 67.3 bits (157), Expect = 7e-11
Identities = 49/180 (27%), Positives = 83/180 (46%), Gaps = 9/180 (5%)
Frame = +1
Query: 67 LLPFLLTCAIASAAECENATSLSLMIDSLL--ATYDRESPP--DSKIVVNLTLHLRHA-- 228
L+ F L A+ C A + ++D LL Y+ P S ++++ L L A
Sbjct: 7 LVLFFLV-ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQL 65
Query: 229 -NIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATT 399
++ E E + L+ W D RL+WN+ + G + + ++R+W PD+VL N A T
Sbjct: 66 ISVNEREQIMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNADGTY 125
Query: 400 AGDYALRARVSNNGSVSWIKRLDISTPISMQLDXWPNDMQTCTFGFGSXMHNIDXMDFVI 579
V +NGSV W+ + +++ +P D Q CT F S ++ +D V+
Sbjct: 126 EVSVYTNLIVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRSWTYDHTEIDMVL 185
>Y08417-1|CAA69694.1| 458|Homo sapiens nicotinic acetylcholine
receptor beta3 subunit precursor protein.
Length = 458
Score = 65.3 bits (152), Expect = 3e-10
Identities = 34/108 (31%), Positives = 53/108 (49%), Gaps = 2/108 (1%)
Frame = +1
Query: 271 LQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLL-NAAATTAGDYALRARVSNNGS 444
L+ W D +L WN ++G + V SE LW PD+VL NA G + V +NG+
Sbjct: 81 LKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFEGSLMTKVIVKSNGT 140
Query: 445 VSWIKRLDISTPISMQLDXWPNDMQTCTFGFGSXMHNIDXMDFVIDXE 588
V W + +M + +P D Q C+ FGS ++ +D ++ E
Sbjct: 141 VVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGTMVDLILINE 188
>X67513-1|CAA47851.1| 423|Homo sapiens nicotinic acetylcholine
receptor beta-3 subunit protein.
Length = 423
Score = 65.3 bits (152), Expect = 3e-10
Identities = 34/108 (31%), Positives = 53/108 (49%), Gaps = 2/108 (1%)
Frame = +1
Query: 271 LQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLL-NAAATTAGDYALRARVSNNGS 444
L+ W D +L WN ++G + V SE LW PD+VL NA G + V +NG+
Sbjct: 46 LKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFEGSLMTKVIVKSNGT 105
Query: 445 VSWIKRLDISTPISMQLDXWPNDMQTCTFGFGSXMHNIDXMDFVIDXE 588
V W + +M + +P D Q C+ FGS ++ +D ++ E
Sbjct: 106 VVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGTMVDLILINE 153
>U62438-1|AAB40116.1| 458|Homo sapiens nicotinic acetylcholine
receptor beta3 subunit precursor protein.
Length = 458
Score = 65.3 bits (152), Expect = 3e-10
Identities = 34/108 (31%), Positives = 53/108 (49%), Gaps = 2/108 (1%)
Frame = +1
Query: 271 LQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLL-NAAATTAGDYALRARVSNNGS 444
L+ W D +L WN ++G + V SE LW PD+VL NA G + V +NG+
Sbjct: 81 LKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFEGSLMTKVIVKSNGT 140
Query: 445 VSWIKRLDISTPISMQLDXWPNDMQTCTFGFGSXMHNIDXMDFVIDXE 588
V W + +M + +P D Q C+ FGS ++ +D ++ E
Sbjct: 141 VVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGTMVDLILINE 188
>BC069788-1|AAH69788.1| 458|Homo sapiens cholinergic receptor,
nicotinic, beta 3 protein.
Length = 458
Score = 65.3 bits (152), Expect = 3e-10
Identities = 34/108 (31%), Positives = 53/108 (49%), Gaps = 2/108 (1%)
Frame = +1
Query: 271 LQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLL-NAAATTAGDYALRARVSNNGS 444
L+ W D +L WN ++G + V SE LW PD+VL NA G + V +NG+
Sbjct: 81 LKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFEGSLMTKVIVKSNGT 140
Query: 445 VSWIKRLDISTPISMQLDXWPNDMQTCTFGFGSXMHNIDXMDFVIDXE 588
V W + +M + +P D Q C+ FGS ++ +D ++ E
Sbjct: 141 VVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGTMVDLILINE 188
>BC069703-1|AAH69703.1| 458|Homo sapiens cholinergic receptor,
nicotinic, beta 3 protein.
Length = 458
Score = 65.3 bits (152), Expect = 3e-10
Identities = 34/108 (31%), Positives = 53/108 (49%), Gaps = 2/108 (1%)
Frame = +1
Query: 271 LQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLL-NAAATTAGDYALRARVSNNGS 444
L+ W D +L WN ++G + V SE LW PD+VL NA G + V +NG+
Sbjct: 81 LKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFEGSLMTKVIVKSNGT 140
Query: 445 VSWIKRLDISTPISMQLDXWPNDMQTCTFGFGSXMHNIDXMDFVIDXE 588
V W + +M + +P D Q C+ FGS ++ +D ++ E
Sbjct: 141 VVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGTMVDLILINE 188
>BC069681-1|AAH69681.1| 458|Homo sapiens cholinergic receptor,
nicotinic, beta 3 protein.
Length = 458
Score = 65.3 bits (152), Expect = 3e-10
Identities = 34/108 (31%), Positives = 53/108 (49%), Gaps = 2/108 (1%)
Frame = +1
Query: 271 LQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLL-NAAATTAGDYALRARVSNNGS 444
L+ W D +L WN ++G + V SE LW PD+VL NA G + V +NG+
Sbjct: 81 LKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFEGSLMTKVIVKSNGT 140
Query: 445 VSWIKRLDISTPISMQLDXWPNDMQTCTFGFGSXMHNIDXMDFVIDXE 588
V W + +M + +P D Q C+ FGS ++ +D ++ E
Sbjct: 141 VVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGTMVDLILINE 188
>AF140765-1|AAD33063.1| 458|Homo sapiens neuronal acetylcholine
receptor beta-3 subunit precursor protein.
Length = 458
Score = 65.3 bits (152), Expect = 3e-10
Identities = 34/108 (31%), Positives = 53/108 (49%), Gaps = 2/108 (1%)
Frame = +1
Query: 271 LQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLL-NAAATTAGDYALRARVSNNGS 444
L+ W D +L WN ++G + V SE LW PD+VL NA G + V +NG+
Sbjct: 81 LKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFEGSLMTKVIVKSNGT 140
Query: 445 VSWIKRLDISTPISMQLDXWPNDMQTCTFGFGSXMHNIDXMDFVIDXE 588
V W + +M + +P D Q C+ FGS ++ +D ++ E
Sbjct: 141 VVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGTMVDLILINE 188
>BT006897-1|AAP35543.1| 505|Homo sapiens cholinergic receptor,
nicotinic, alpha polypeptide 3 protein.
Length = 505
Score = 64.5 bits (150), Expect = 5e-10
Identities = 44/183 (24%), Positives = 84/183 (45%), Gaps = 5/183 (2%)
Frame = +1
Query: 46 MSTTYIILLPFLLTCAIASAAECENATSLSLMID--SLLATYDRESPPDSKIVVNLTLHL 219
+S ++LL L +A A+E E+ L D ++ S P ++++ + +
Sbjct: 12 LSPPRLLLLLLLSLLPVARASEAEHRLFERLFEDYNEIIRPVANVSDP---VIIHFEVSM 68
Query: 220 RH-ANIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AA 390
+ E + L+ W D +L WN ++G + ++ V ++++W+PD+VL N A
Sbjct: 69 SQLVKVDEVNQIMETNLWLKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAV 128
Query: 391 ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDXWPNDMQTCTFGFGSXMHNIDXMD 570
D +A + G V+WI + + + +P D Q CT FGS ++ +D
Sbjct: 129 GDFQVDDKTKALLKYTGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKID 188
Query: 571 FVI 579
V+
Sbjct: 189 LVL 191
>BT006646-1|AAP35292.1| 489|Homo sapiens cholinergic receptor,
nicotinic, alpha polypeptide 3 protein.
Length = 489
Score = 64.5 bits (150), Expect = 5e-10
Identities = 44/183 (24%), Positives = 84/183 (45%), Gaps = 5/183 (2%)
Frame = +1
Query: 46 MSTTYIILLPFLLTCAIASAAECENATSLSLMID--SLLATYDRESPPDSKIVVNLTLHL 219
+S ++LL L +A A+E E+ L D ++ S P ++++ + +
Sbjct: 12 LSPPRLLLLLLLSLLPVARASEAEHRLFERLFEDYNEIIRPVANVSDP---VIIHFEVSM 68
Query: 220 RH-ANIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AA 390
+ E + L+ W D +L WN ++G + ++ V ++++W+PD+VL N A
Sbjct: 69 SQLVKVDEVNQIMETNLWLKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAV 128
Query: 391 ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDXWPNDMQTCTFGFGSXMHNIDXMD 570
D +A + G V+WI + + + +P D Q CT FGS ++ +D
Sbjct: 129 GDFQVDDKTKALLKYTGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKID 188
Query: 571 FVI 579
V+
Sbjct: 189 LVL 191
>BC006114-1|AAH06114.1| 489|Homo sapiens CHRNA3 protein protein.
Length = 489
Score = 64.5 bits (150), Expect = 5e-10
Identities = 44/183 (24%), Positives = 84/183 (45%), Gaps = 5/183 (2%)
Frame = +1
Query: 46 MSTTYIILLPFLLTCAIASAAECENATSLSLMID--SLLATYDRESPPDSKIVVNLTLHL 219
+S ++LL L +A A+E E+ L D ++ S P ++++ + +
Sbjct: 12 LSPPRLLLLLLLSLLPVARASEAEHRLFERLFEDYNEIIRPVANVSDP---VIIHFEVSM 68
Query: 220 RH-ANIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AA 390
+ E + L+ W D +L WN ++G + ++ V ++++W+PD+VL N A
Sbjct: 69 SQLVKVDEVNQIMETNLWLKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAV 128
Query: 391 ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDXWPNDMQTCTFGFGSXMHNIDXMD 570
D +A + G V+WI + + + +P D Q CT FGS ++ +D
Sbjct: 129 GDFQVDDKTKALLKYTGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKID 188
Query: 571 FVI 579
V+
Sbjct: 189 LVL 191
>BC002996-1|AAH02996.1| 505|Homo sapiens cholinergic receptor,
nicotinic, alpha 3 protein.
Length = 505
Score = 64.5 bits (150), Expect = 5e-10
Identities = 44/183 (24%), Positives = 84/183 (45%), Gaps = 5/183 (2%)
Frame = +1
Query: 46 MSTTYIILLPFLLTCAIASAAECENATSLSLMID--SLLATYDRESPPDSKIVVNLTLHL 219
+S ++LL L +A A+E E+ L D ++ S P ++++ + +
Sbjct: 12 LSPPRLLLLLLLSLLPVARASEAEHRLFERLFEDYNEIIRPVANVSDP---VIIHFEVSM 68
Query: 220 RH-ANIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AA 390
+ E + L+ W D +L WN ++G + ++ V ++++W+PD+VL N A
Sbjct: 69 SQLVKVDEVNQIMETNLWLKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAV 128
Query: 391 ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDXWPNDMQTCTFGFGSXMHNIDXMD 570
D +A + G V+WI + + + +P D Q CT FGS ++ +D
Sbjct: 129 GDFQVDDKTKALLKYTGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKID 188
Query: 571 FVI 579
V+
Sbjct: 189 LVL 191
>BC001642-1|AAH01642.1| 505|Homo sapiens cholinergic receptor,
nicotinic, alpha 3 protein.
Length = 505
Score = 64.5 bits (150), Expect = 5e-10
Identities = 44/183 (24%), Positives = 84/183 (45%), Gaps = 5/183 (2%)
Frame = +1
Query: 46 MSTTYIILLPFLLTCAIASAAECENATSLSLMID--SLLATYDRESPPDSKIVVNLTLHL 219
+S ++LL L +A A+E E+ L D ++ S P ++++ + +
Sbjct: 12 LSPPRLLLLLLLSLLPVARASEAEHRLFERLFEDYNEIIRPVANVSDP---VIIHFEVSM 68
Query: 220 RH-ANIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AA 390
+ E + L+ W D +L WN ++G + ++ V ++++W+PD+VL N A
Sbjct: 69 SQLVKVDEVNQIMETNLWLKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAV 128
Query: 391 ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDXWPNDMQTCTFGFGSXMHNIDXMD 570
D +A + G V+WI + + + +P D Q CT FGS ++ +D
Sbjct: 129 GDFQVDDKTKALLKYTGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKID 188
Query: 571 FVI 579
V+
Sbjct: 189 LVL 191
>BC000513-1|AAH00513.1| 505|Homo sapiens cholinergic receptor,
nicotinic, alpha 3 protein.
Length = 505
Score = 64.5 bits (150), Expect = 5e-10
Identities = 44/183 (24%), Positives = 84/183 (45%), Gaps = 5/183 (2%)
Frame = +1
Query: 46 MSTTYIILLPFLLTCAIASAAECENATSLSLMID--SLLATYDRESPPDSKIVVNLTLHL 219
+S ++LL L +A A+E E+ L D ++ S P ++++ + +
Sbjct: 12 LSPPRLLLLLLLSLLPVARASEAEHRLFERLFEDYNEIIRPVANVSDP---VIIHFEVSM 68
Query: 220 RH-ANIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AA 390
+ E + L+ W D +L WN ++G + ++ V ++++W+PD+VL N A
Sbjct: 69 SQLVKVDEVNQIMETNLWLKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAV 128
Query: 391 ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDXWPNDMQTCTFGFGSXMHNIDXMD 570
D +A + G V+WI + + + +P D Q CT FGS ++ +D
Sbjct: 129 GDFQVDDKTKALLKYTGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKID 188
Query: 571 FVI 579
V+
Sbjct: 189 LVL 191
>AF385584-1|AAK68110.1| 489|Homo sapiens nicotinic cholinergic
receptor alpha 3 protein.
Length = 489
Score = 64.5 bits (150), Expect = 5e-10
Identities = 44/183 (24%), Positives = 84/183 (45%), Gaps = 5/183 (2%)
Frame = +1
Query: 46 MSTTYIILLPFLLTCAIASAAECENATSLSLMID--SLLATYDRESPPDSKIVVNLTLHL 219
+S ++LL L +A A+E E+ L D ++ S P ++++ + +
Sbjct: 6 LSPPRLLLLLLLSLLPVARASEAEHRLFERLFEDYNEIIRPVANVSDP---VIIHFEVSM 62
Query: 220 RH-ANIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AA 390
+ E + L+ W D +L WN ++G + ++ V ++++W+PD+VL N A
Sbjct: 63 SQLVKVDEVNQIMETNLWLKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAV 122
Query: 391 ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDXWPNDMQTCTFGFGSXMHNIDXMD 570
D +A + G V+WI + + + +P D Q CT FGS ++ +D
Sbjct: 123 GDFQVDDKTKALLKYTGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKID 182
Query: 571 FVI 579
V+
Sbjct: 183 LVL 185
>Y08419-1|CAA69696.1| 468|Homo sapiens nicotinic acetylcholine
receptor alpha5 subunit precursor protein.
Length = 468
Score = 63.7 bits (148), Expect = 8e-10
Identities = 36/156 (23%), Positives = 73/156 (46%), Gaps = 6/156 (3%)
Frame = +1
Query: 139 MIDSLLATYDRESPP----DSKIVVNLTLHLRH-ANIRESESTVRILADLQMNWIDKRLS 303
++ L Y+R P + KI + L + ++ E + L+ WID +L
Sbjct: 50 LLKDLFQDYERWVRPVEHLNDKIKIKFGLAISQLVDVDEKNQLMTTNVWLKQEWIDVKLR 109
Query: 304 WNAGEWG-CSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVSWIKRLDISTP 480
WN ++G V S+ +W PD+VL + A + + + NG+V+W + +
Sbjct: 110 WNPDDYGGIKVIRVPSDSVWTPDIVLFDNADGRFEGTSTKTVIRYNGTVTWTPPANYKSS 169
Query: 481 ISMQLDXWPNDMQTCTFGFGSXMHNIDXMDFVIDXE 588
++ + +P D+Q C+ FGS ++ +D +++ +
Sbjct: 170 CTIDVTFFPFDLQNCSMKFGSWTYDGSQVDIILEDQ 205
>Y08418-1|CAA69695.1| 503|Homo sapiens nicotinic acetylcholine
receptor alpha3 subunit precursor protein.
Length = 503
Score = 63.7 bits (148), Expect = 8e-10
Identities = 44/176 (25%), Positives = 81/176 (46%), Gaps = 3/176 (1%)
Frame = +1
Query: 61 IILLPFLLTCAIASAAECENATSLSLMIDSLLATYDRESPPDSKIVVNLTLHLRH-ANIR 237
++LL LL A AS AE L + ++ S P ++++ + + +
Sbjct: 17 LLLLLSLLPVARASEAEHRLFERLFEDYNEIIRPVANVSDP---VIIHFEVSMSQLVKVD 73
Query: 238 ESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDY 411
E + L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D
Sbjct: 74 EVNQIMETNLWLKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDD 133
Query: 412 ALRARVSNNGSVSWIKRLDISTPISMQLDXWPNDMQTCTFGFGSXMHNIDXMDFVI 579
+A + G V+WI + + + +P D Q CT FGS ++ +D V+
Sbjct: 134 KTKALLKYTGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVL 189
>U62434-1|AAB40112.1| 468|Homo sapiens nicotinic acetylcholine
receptor alpha5 subunit precursor protein.
Length = 468
Score = 63.7 bits (148), Expect = 8e-10
Identities = 36/156 (23%), Positives = 73/156 (46%), Gaps = 6/156 (3%)
Frame = +1
Query: 139 MIDSLLATYDRESPP----DSKIVVNLTLHLRH-ANIRESESTVRILADLQMNWIDKRLS 303
++ L Y+R P + KI + L + ++ E + L+ WID +L
Sbjct: 50 LLKDLFQDYERWVRPVEHLNDKIKIKFGLAISQLVDVDEKNQLMTTNVWLKQEWIDVKLR 109
Query: 304 WNAGEWG-CSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVSWIKRLDISTP 480
WN ++G V S+ +W PD+VL + A + + + NG+V+W + +
Sbjct: 110 WNPDDYGGIKVIRVPSDSVWTPDIVLFDNADGRFEGTSTKTVIRYNGTVTWTPPANYKSS 169
Query: 481 ISMQLDXWPNDMQTCTFGFGSXMHNIDXMDFVIDXE 588
++ + +P D+Q C+ FGS ++ +D +++ +
Sbjct: 170 CTIDVTFFPFDLQNCSMKFGSWTYDGSQVDIILEDQ 205
>U62432-1|AAB40110.1| 504|Homo sapiens nicotinic acetylcholine
receptor alpha3 subunit precursor protein.
Length = 504
Score = 63.7 bits (148), Expect = 8e-10
Identities = 44/176 (25%), Positives = 81/176 (46%), Gaps = 3/176 (1%)
Frame = +1
Query: 61 IILLPFLLTCAIASAAECENATSLSLMIDSLLATYDRESPPDSKIVVNLTLHLRH-ANIR 237
++LL LL A AS AE L + ++ S P ++++ + + +
Sbjct: 18 LLLLLSLLPVARASEAEHRLFERLFEDYNEIIRPVANVSDP---VIIHFEVSMSQLVKVD 74
Query: 238 ESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDY 411
E + L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D
Sbjct: 75 EVNQIMETNLWLKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDD 134
Query: 412 ALRARVSNNGSVSWIKRLDISTPISMQLDXWPNDMQTCTFGFGSXMHNIDXMDFVI 579
+A + G V+WI + + + +P D Q CT FGS ++ +D V+
Sbjct: 135 KTKALLKYTGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVL 190
>M37981-1|AAA59942.1| 503|Homo sapiens neuronal nicotinic
acetylcholine receptor protein.
Length = 503
Score = 63.7 bits (148), Expect = 8e-10
Identities = 44/176 (25%), Positives = 81/176 (46%), Gaps = 3/176 (1%)
Frame = +1
Query: 61 IILLPFLLTCAIASAAECENATSLSLMIDSLLATYDRESPPDSKIVVNLTLHLRH-ANIR 237
++LL LL A AS AE L + ++ S P ++++ + + +
Sbjct: 17 LLLLLSLLPVARASEAEHRLFERLFEDYNEIIRPVANVSDP---VIIHFEVSMSQLVKVD 73
Query: 238 ESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDY 411
E + L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D
Sbjct: 74 EVNQIMETNLWLKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDD 133
Query: 412 ALRARVSNNGSVSWIKRLDISTPISMQLDXWPNDMQTCTFGFGSXMHNIDXMDFVI 579
+A + G V+WI + + + +P D Q CT FGS ++ +D V+
Sbjct: 134 KTKALLKYTGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVL 189
>BC098443-1|AAH98443.1| 504|Homo sapiens cholinergic receptor,
nicotinic, alpha 3 protein.
Length = 504
Score = 63.7 bits (148), Expect = 8e-10
Identities = 44/176 (25%), Positives = 81/176 (46%), Gaps = 3/176 (1%)
Frame = +1
Query: 61 IILLPFLLTCAIASAAECENATSLSLMIDSLLATYDRESPPDSKIVVNLTLHLRH-ANIR 237
++LL LL A AS AE L + ++ S P ++++ + + +
Sbjct: 18 LLLLLSLLPVARASEAEHRLFERLFEDYNEIIRPVANVSDP---VIIHFEVSMSQLVKVD 74
Query: 238 ESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDY 411
E + L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D
Sbjct: 75 EVNQIMETNLWLKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDD 134
Query: 412 ALRARVSNNGSVSWIKRLDISTPISMQLDXWPNDMQTCTFGFGSXMHNIDXMDFVI 579
+A + G V+WI + + + +P D Q CT FGS ++ +D V+
Sbjct: 135 KTKALLKYTGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVL 190
>BC033639-1|AAH33639.1| 468|Homo sapiens cholinergic receptor,
nicotinic, alpha 5 protein.
Length = 468
Score = 63.7 bits (148), Expect = 8e-10
Identities = 36/156 (23%), Positives = 73/156 (46%), Gaps = 6/156 (3%)
Frame = +1
Query: 139 MIDSLLATYDRESPP----DSKIVVNLTLHLRH-ANIRESESTVRILADLQMNWIDKRLS 303
++ L Y+R P + KI + L + ++ E + L+ WID +L
Sbjct: 50 LLKDLFQDYERWVRPVEHLNDKIKIKFGLAISQLVDVDEKNQLMTTNVWLKQEWIDVKLR 109
Query: 304 WNAGEWG-CSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVSWIKRLDISTP 480
WN ++G V S+ +W PD+VL + A + + + NG+V+W + +
Sbjct: 110 WNPDDYGGIKVIRVPSDSVWTPDIVLFDNADGRFEGTSTKTVIRYNGTVTWTPPANYKSS 169
Query: 481 ISMQLDXWPNDMQTCTFGFGSXMHNIDXMDFVIDXE 588
++ + +P D+Q C+ FGS ++ +D +++ +
Sbjct: 170 CTIDVTFFPFDLQNCSMKFGSWTYDGSQVDIILEDQ 205
>AJ306481-1|CAC34820.1| 468|Homo sapiens neuronal nicotinic
acetylcholine receptor alpha-5subunit protein.
Length = 468
Score = 63.7 bits (148), Expect = 8e-10
Identities = 36/156 (23%), Positives = 73/156 (46%), Gaps = 6/156 (3%)
Frame = +1
Query: 139 MIDSLLATYDRESPP----DSKIVVNLTLHLRH-ANIRESESTVRILADLQMNWIDKRLS 303
++ L Y+R P + KI + L + ++ E + L+ WID +L
Sbjct: 50 LLKDLFQDYERWVRPVEHLNDKIKIKFGLAISQLVDVDEKNQLMTTNVWLKQEWIDVKLR 109
Query: 304 WNAGEWG-CSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVSWIKRLDISTP 480
WN ++G V S+ +W PD+VL + A + + + NG+V+W + +
Sbjct: 110 WNPDDYGGIKVIRVPSDSVWTPDIVLFDNADGRFEGTSTKTVIRYNGTVTWTPPANYKSS 169
Query: 481 ISMQLDXWPNDMQTCTFGFGSXMHNIDXMDFVIDXE 588
++ + +P D+Q C+ FGS ++ +D +++ +
Sbjct: 170 CTIDVTFFPFDLQNCSMKFGSWTYDGSQVDIILEDQ 205
>AJ007783-1|CAA07682.1| 504|Homo sapiens nicotinic acetylcholine
receptor alpha-3 subunit protein.
Length = 504
Score = 63.7 bits (148), Expect = 8e-10
Identities = 44/176 (25%), Positives = 81/176 (46%), Gaps = 3/176 (1%)
Frame = +1
Query: 61 IILLPFLLTCAIASAAECENATSLSLMIDSLLATYDRESPPDSKIVVNLTLHLRH-ANIR 237
++LL LL A AS AE L + ++ S P ++++ + + +
Sbjct: 18 LLLLLSLLPVARASEAEHRLFERLFEDYNEIIRPVANVSDP---VIIHFEVSMSQLVKVD 74
Query: 238 ESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDY 411
E + L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D
Sbjct: 75 EVNQIMETNLWLKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDD 134
Query: 412 ALRARVSNNGSVSWIKRLDISTPISMQLDXWPNDMQTCTFGFGSXMHNIDXMDFVI 579
+A + G V+WI + + + +P D Q CT FGS ++ +D V+
Sbjct: 135 KTKALLKYTGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVL 190
>X68275-1|CAA48336.1| 451|Homo sapiens nicotinic receptor beta 4
subunit protein.
Length = 451
Score = 62.9 bits (146), Expect = 1e-09
Identities = 37/132 (28%), Positives = 63/132 (47%), Gaps = 3/132 (2%)
Frame = +1
Query: 193 IVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 366
I + L L L ++ E + + L+ W D RL+WN+ + G + + ++R+W P
Sbjct: 7 ISIKLQLSLAQLISVNERDEIMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLP 66
Query: 367 DVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDXWPNDMQTCTFGFGS 543
D+VL N A T V +NGSV W+ + +++ +P D Q CT F S
Sbjct: 67 DIVLYNNADGTYEVSVYTNLIVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRS 126
Query: 544 XMHNIDXMDFVI 579
++ +D V+
Sbjct: 127 WTYDHTEIDMVL 138
>X53559-1|CAA37625.1| 474|Homo sapiens neuronal nicotinic
acetylcholine receptor alpha-3merase protein.
Length = 474
Score = 62.9 bits (146), Expect = 1e-09
Identities = 31/105 (29%), Positives = 55/105 (52%), Gaps = 2/105 (1%)
Frame = +1
Query: 271 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 444
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 56 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 115
Query: 445 VSWIKRLDISTPISMQLDXWPNDMQTCTFGFGSXMHNIDXMDFVI 579
V+WI + + + +P D Q CT FGS ++ +D V+
Sbjct: 116 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVL 160
>M83712-1|AAA58357.1| 468|Homo sapiens nicotinic receptor alpha 5
subunit protein.
Length = 468
Score = 62.5 bits (145), Expect = 2e-09
Identities = 36/156 (23%), Positives = 72/156 (46%), Gaps = 6/156 (3%)
Frame = +1
Query: 139 MIDSLLATYDRESPP----DSKIVVNLTLHLRH-ANIRESESTVRILADLQMNWIDKRLS 303
++ L Y+R P + KI + L + ++ E + L+ WID +L
Sbjct: 50 LLKDLFQDYERWVRPVEHLNDKIKIKFGLAISQLVDVDEKNQLMTTNVWLKQEWIDVKLR 109
Query: 304 WNAGEWG-CSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVSWIKRLDISTP 480
WN ++G V S+ W PD+VL + A + + + NG+V+W + +
Sbjct: 110 WNPDDYGGIKVIRVPSDSSWTPDIVLFDNADGRFEGTSTKTVIRYNGTVTWTPPANYKSS 169
Query: 481 ISMQLDXWPNDMQTCTFGFGSXMHNIDXMDFVIDXE 588
++ + +P D+Q C+ FGS ++ +D +++ +
Sbjct: 170 CTIDVTFFPFDLQNCSMKFGSWTYDGSQVDIILEDQ 205
>X14830-1|CAA32939.1| 501|Homo sapiens protein ( Human mRNA for
muscle acetylcholine receptor beta-subunit. ).
Length = 501
Score = 61.3 bits (142), Expect = 4e-09
Identities = 45/133 (33%), Positives = 67/133 (50%), Gaps = 4/133 (3%)
Frame = +1
Query: 169 RESPPDSKIVVNLTL-HLRHANIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLV 342
RE ++ V L L L N ++ E + ++ DL+ W D RLSW+ E G + +
Sbjct: 46 REVGDRVRVSVGLILAQLISLNEKDEEMSTKVYLDLE--WTDYRLSWDPAEHDGIDSLRI 103
Query: 343 SSERLWRPDVVLLNAAATTAGDYAL--RARVSNNGSVSWIKRLDISTPISMQLDXWPNDM 516
++E +W PDVVLLN D AL VS++GSV W + S+Q+ +P D
Sbjct: 104 TAESVWLPDVVLLNNNDGNF-DVALDISVVVSSDGSVRWQPPGIYRSSCSIQVTYFPFDW 162
Query: 517 QTCTFGFGSXMHN 555
Q CT F S ++
Sbjct: 163 QNCTMVFSSYSYD 175
>M86383-1|AAC84176.1| 502|Homo sapiens nicotinic acetylcholine
receptor alpha 3 subunit precursor protein.
Length = 502
Score = 61.3 bits (142), Expect = 4e-09
Identities = 45/179 (25%), Positives = 83/179 (46%), Gaps = 6/179 (3%)
Frame = +1
Query: 61 IILLPFLLTCAIASAAECENATSLSLMIDSLLATYDRESPPDSKIVVNLTLHLRH-ANIR 237
++LL LL A AS AE L + ++ S P ++++ + + +
Sbjct: 16 LLLLLSLLPVARASEAEHRLFERLFEDYNEIIRPVANVSDP---VIIHFEVSMSQLVKVD 72
Query: 238 ESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYA 414
E + L+ W D +L WN +G + ++ V ++++W+PD+VL N A GD+
Sbjct: 73 EVNQIMETNLWLKQIWNDYKLKWNPSGYGGAEFMRVPAQKIWKPDIVLYNNAV---GDFQ 129
Query: 415 L----RARVSNNGSVSWIKRLDISTPISMQLDXWPNDMQTCTFGFGSXMHNIDXMDFVI 579
+ +A + G V+WI + + + +P D Q CT FGS ++ +D V+
Sbjct: 130 VTTKTKALLKYTGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVL 188
>BC011371-1|AAH11371.1| 501|Homo sapiens cholinergic receptor,
nicotinic, beta 1 (muscle) protein.
Length = 501
Score = 61.3 bits (142), Expect = 4e-09
Identities = 45/133 (33%), Positives = 67/133 (50%), Gaps = 4/133 (3%)
Frame = +1
Query: 169 RESPPDSKIVVNLTL-HLRHANIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLV 342
RE ++ V L L L N ++ E + ++ DL+ W D RLSW+ E G + +
Sbjct: 46 REVGDRVRVSVGLILAQLISLNEKDEEMSTKVYLDLE--WTDYRLSWDPAEHDGIDSLRI 103
Query: 343 SSERLWRPDVVLLNAAATTAGDYAL--RARVSNNGSVSWIKRLDISTPISMQLDXWPNDM 516
++E +W PDVVLLN D AL VS++GSV W + S+Q+ +P D
Sbjct: 104 TAESVWLPDVVLLNNNDGNF-DVALDISVVVSSDGSVRWQPPGIYRSSCSIQVTYFPFDW 162
Query: 517 QTCTFGFGSXMHN 555
Q CT F S ++
Sbjct: 163 QNCTMVFSSYSYD 175
>Y16282-1|CAA76155.1| 494|Homo sapiens nicotinic acetylcholine
receptor alpha6 subunit precursor protein.
Length = 494
Score = 60.9 bits (141), Expect = 6e-09
Identities = 41/166 (24%), Positives = 76/166 (45%), Gaps = 10/166 (6%)
Frame = +1
Query: 112 CENATSLSLMIDSLLATYDRESPPDSKIVVNLTLHL-----RHANIRESESTVRILADLQ 276
C + + L + Y++ P + +T+H + AN+ E + L+
Sbjct: 28 CVGCATEERLFHKLFSHYNQFIRPVENVSDPVTVHFEVAITQLANVDEVNQIMETNLWLR 87
Query: 277 MNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNG 441
W D +L W+ E+ G T V ++++W+PD+VL N A GD+ + +A + NG
Sbjct: 88 HIWNDYKLRWDPMEYDGIETLRVPADKIWKPDIVLYNNAV---GDFQVEGKTKALLKYNG 144
Query: 442 SVSWIKRLDISTPISMQLDXWPNDMQTCTFGFGSXMHNIDXMDFVI 579
++W + M + +P D Q C+ FGS ++ +D +I
Sbjct: 145 MITWTPPAIFKSSCPMDITFFPFDHQNCSLKFGSWTYDKAEIDLLI 190
>Y16281-1|CAA76154.1| 529|Homo sapiens nicotinic acetylcholine
receptor alpha2 subunit precursor protein.
Length = 529
Score = 60.9 bits (141), Expect = 6e-09
Identities = 33/102 (32%), Positives = 52/102 (50%), Gaps = 2/102 (1%)
Frame = +1
Query: 271 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAA-ATTAGDYALRARVSNNGS 444
L+ W D +L WN ++G T L V SE +W PD+VL N A A + +A + + G+
Sbjct: 111 LKQEWSDYKLRWNPADFGNITSLRVPSEMIWIPDIVLYNNADGEFAVTHMTKAHLFSTGT 170
Query: 445 VSWIKRLDISTPISMQLDXWPNDMQTCTFGFGSXMHNIDXMD 570
V W+ + S+ + +P D Q C FGS ++ +D
Sbjct: 171 VHWVPPAIYKSSCSIDVTFFPFDQQNCKMKFGSWTYDKAKID 212
>U62435-1|AAB40113.1| 494|Homo sapiens nicotinic acetylcholine
receptor alpha6 subunit precursor protein.
Length = 494
Score = 60.9 bits (141), Expect = 6e-09
Identities = 41/166 (24%), Positives = 76/166 (45%), Gaps = 10/166 (6%)
Frame = +1
Query: 112 CENATSLSLMIDSLLATYDRESPPDSKIVVNLTLHL-----RHANIRESESTVRILADLQ 276
C + + L + Y++ P + +T+H + AN+ E + L+
Sbjct: 28 CVGCATEERLFHKLFSHYNQFIRPVENVSDPVTVHFEVAITQLANVDEVNQIMETNLWLR 87
Query: 277 MNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNG 441
W D +L W+ E+ G T V ++++W+PD+VL N A GD+ + +A + NG
Sbjct: 88 HIWNDYKLRWDPMEYDGIETLRVPADKIWKPDIVLYNNAV---GDFQVEGKTKALLKYNG 144
Query: 442 SVSWIKRLDISTPISMQLDXWPNDMQTCTFGFGSXMHNIDXMDFVI 579
++W + M + +P D Q C+ FGS ++ +D +I
Sbjct: 145 MITWTPPAIFKSSCPMDITFFPFDHQNCSLKFGSWTYDKAEIDLLI 190
>U62431-1|AAB40109.1| 529|Homo sapiens nicotinic acetylcholine
receptor alpha2 subunit precursor protein.
Length = 529
Score = 60.9 bits (141), Expect = 6e-09
Identities = 33/102 (32%), Positives = 52/102 (50%), Gaps = 2/102 (1%)
Frame = +1
Query: 271 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAA-ATTAGDYALRARVSNNGS 444
L+ W D +L WN ++G T L V SE +W PD+VL N A A + +A + + G+
Sbjct: 111 LKQEWSDYKLRWNPADFGNITSLRVPSEMIWIPDIVLYNNADGEFAVTHMTKAHLFSTGT 170
Query: 445 VSWIKRLDISTPISMQLDXWPNDMQTCTFGFGSXMHNIDXMD 570
V W+ + S+ + +P D Q C FGS ++ +D
Sbjct: 171 VHWVPPAIYKSSCSIDVTFFPFDQQNCKMKFGSWTYDKAKID 212
>BC014456-1|AAH14456.1| 494|Homo sapiens cholinergic receptor,
nicotinic, alpha 6 protein.
Length = 494
Score = 60.9 bits (141), Expect = 6e-09
Identities = 41/166 (24%), Positives = 76/166 (45%), Gaps = 10/166 (6%)
Frame = +1
Query: 112 CENATSLSLMIDSLLATYDRESPPDSKIVVNLTLHL-----RHANIRESESTVRILADLQ 276
C + + L + Y++ P + +T+H + AN+ E + L+
Sbjct: 28 CVGCATEERLFHKLFSHYNQFIRPVENVSDPVTVHFEVAITQLANVDEVNQIMETNLWLR 87
Query: 277 MNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNG 441
W D +L W+ E+ G T V ++++W+PD+VL N A GD+ + +A + NG
Sbjct: 88 HIWNDYKLRWDPMEYDGIETLRVPADKIWKPDIVLYNNAV---GDFQVEGKTKALLKYNG 144
Query: 442 SVSWIKRLDISTPISMQLDXWPNDMQTCTFGFGSXMHNIDXMDFVI 579
++W + M + +P D Q C+ FGS ++ +D +I
Sbjct: 145 MITWTPPAIFKSSCPMDITFFPFDHQNCSLKFGSWTYDKAEIDLLI 190
>AB079251-1|BAC06855.1| 494|Homo sapiens Nicotinic acetylcholine
receptor alpha 6 protein.
Length = 494
Score = 60.9 bits (141), Expect = 6e-09
Identities = 41/166 (24%), Positives = 76/166 (45%), Gaps = 10/166 (6%)
Frame = +1
Query: 112 CENATSLSLMIDSLLATYDRESPPDSKIVVNLTLHL-----RHANIRESESTVRILADLQ 276
C + + L + Y++ P + +T+H + AN+ E + L+
Sbjct: 28 CVGCATEERLFHKLFSHYNQFIRPVENVSDPVTVHFEVAITQLANVDEVNQIMETNLWLR 87
Query: 277 MNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNG 441
W D +L W+ E+ G T V ++++W+PD+VL N A GD+ + +A + NG
Sbjct: 88 HIWNDYKLRWDPMEYDGIETLRVPADKIWKPDIVLYNNAV---GDFQVEGKTKALLKYNG 144
Query: 442 SVSWIKRLDISTPISMQLDXWPNDMQTCTFGFGSXMHNIDXMDFVI 579
++W + M + +P D Q C+ FGS ++ +D +I
Sbjct: 145 MITWTPPAIFKSSCPMDITFFPFDHQNCSLKFGSWTYDKAEIDLLI 190
>DQ644022-1|ABG35128.1| 456|Homo sapiens 5-HT3 receptor subunit E
splice variant HTR3Ea protein.
Length = 456
Score = 60.5 bits (140), Expect = 8e-09
Identities = 47/199 (23%), Positives = 90/199 (45%), Gaps = 8/199 (4%)
Frame = +1
Query: 40 HKMSTTYIILLPFLLTC-AIASAAECENATSLSLMIDSLLATYDRES-PPDSKIVVNLTL 213
H+ ++ +LL FLL + C +L + ++R+ P + I V +
Sbjct: 7 HRKRFSFYLLLGFLLQGRGVTFTINCSGFGQHGADPTALNSVFNRKPFRPVTNISVPTQV 66
Query: 214 HLRHAN--IRESESTVRILAD---LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVV 375
++ A I + + +L+ L+M W + +SWN E G + ++++ LW PD+
Sbjct: 67 NISFAMSAILDVNEQLHLLSSFLWLEMVWDNPFISWNPEECEGITKMSMAAKNLWLPDIF 126
Query: 376 LLNAAATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDXWPNDMQTCTFGFGSXMHN 555
++ L A VSN G + + K + + + ++ + +P D Q CT F S ++
Sbjct: 127 IIELMDVDKTPKGLTAYVSNEGRIRYKKPMKVDSICNLDIFYFPFDQQNCTLTFSSFLYT 186
Query: 556 IDXMDFVIDXEYTVCSXQD 612
+D M ++D E V D
Sbjct: 187 VDSM--LLDMEKEVWEITD 203
>Y08421-1|CAA69698.1| 627|Homo sapiens nicotinic acetylcholine
receptor alpha4 subunit precursor protein.
Length = 627
Score = 60.1 bits (139), Expect = 1e-08
Identities = 48/181 (26%), Positives = 89/181 (49%), Gaps = 11/181 (6%)
Frame = +1
Query: 67 LLPFLLTCAIASAAECEN-ATSLSLMIDSLLATYDRESPPDSKI--VVNLTLHLRHANIR 237
LL L T + +++ E A + ++ L + Y++ S P + I VV + L A +
Sbjct: 15 LLLLLGTGLLRASSHVETRAHAEERLLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLI 74
Query: 238 ESESTVRILAD---LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAG 405
+ + +++ ++ W D +L W+ ++ T + + SE +WRPD+VL N A G
Sbjct: 75 DVDEKNQMMTTNVWVKQEWHDYKLRWDPADYENVTSIRIPSELIWRPDIVLYNNAD---G 131
Query: 406 DYAL----RARVSNNGSVSWIKRLDISTPISMQLDXWPNDMQTCTFGFGSXMHNIDXMDF 573
D+A+ +A + ++G V W + S+ + +P D Q CT FGS ++ +D
Sbjct: 132 DFAVTHLTKAHLFHDGRVQWTPPAIYKSSCSIDVTFFPFDQQNCTMKFGSWTYDKAKIDL 191
Query: 574 V 576
V
Sbjct: 192 V 192
>X89741-1|CAA61893.1| 627|Homo sapiens neuronal acetylcholine
receptor alpha-4 subunit protein.
Length = 627
Score = 60.1 bits (139), Expect = 1e-08
Identities = 48/181 (26%), Positives = 89/181 (49%), Gaps = 11/181 (6%)
Frame = +1
Query: 67 LLPFLLTCAIASAAECEN-ATSLSLMIDSLLATYDRESPPDSKI--VVNLTLHLRHANIR 237
LL L T + +++ E A + ++ L + Y++ S P + I VV + L A +
Sbjct: 15 LLLLLGTGLLRASSHVETRAHAEERLLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLI 74
Query: 238 ESESTVRILAD---LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAG 405
+ + +++ ++ W D +L W+ ++ T + + SE +WRPD+VL N A G
Sbjct: 75 DVDEKNQMMTTNVWVKQEWHDYKLRWDPADYENVTSIRIPSELIWRPDIVLYNNAD---G 131
Query: 406 DYAL----RARVSNNGSVSWIKRLDISTPISMQLDXWPNDMQTCTFGFGSXMHNIDXMDF 573
D+A+ +A + ++G V W + S+ + +P D Q CT FGS ++ +D
Sbjct: 132 DFAVTHLTKAHLFHDGRVQWTPPAIYKSSCSIDVTFFPFDQQNCTMKFGSWTYDKAKIDL 191
Query: 574 V 576
V
Sbjct: 192 V 192
>U62433-1|AAB40111.1| 627|Homo sapiens nicotinic acetylcholine
receptor alpha4 subunit precursor protein.
Length = 627
Score = 60.1 bits (139), Expect = 1e-08
Identities = 48/181 (26%), Positives = 89/181 (49%), Gaps = 11/181 (6%)
Frame = +1
Query: 67 LLPFLLTCAIASAAECEN-ATSLSLMIDSLLATYDRESPPDSKI--VVNLTLHLRHANIR 237
LL L T + +++ E A + ++ L + Y++ S P + I VV + L A +
Sbjct: 15 LLLLLGTGLLRASSHVETRAHAEERLLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLI 74
Query: 238 ESESTVRILAD---LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAG 405
+ + +++ ++ W D +L W+ ++ T + + SE +WRPD+VL N A G
Sbjct: 75 DVDEKNQMMTTNVWVKQEWHDYKLRWDPADYENVTSIRIPSELIWRPDIVLYNNAD---G 131
Query: 406 DYAL----RARVSNNGSVSWIKRLDISTPISMQLDXWPNDMQTCTFGFGSXMHNIDXMDF 573
D+A+ +A + ++G V W + S+ + +P D Q CT FGS ++ +D
Sbjct: 132 DFAVTHLTKAHLFHDGRVQWTPPAIYKSSCSIDVTFFPFDQQNCTMKFGSWTYDKAKIDL 191
Query: 574 V 576
V
Sbjct: 192 V 192
>L35901-1|AAA64743.1| 627|Homo sapiens nicotinic acetylcholine
receptor alpha 4 subunit protein.
Length = 627
Score = 60.1 bits (139), Expect = 1e-08
Identities = 48/181 (26%), Positives = 89/181 (49%), Gaps = 11/181 (6%)
Frame = +1
Query: 67 LLPFLLTCAIASAAECEN-ATSLSLMIDSLLATYDRESPPDSKI--VVNLTLHLRHANIR 237
LL L T + +++ E A + ++ L + Y++ S P + I VV + L A +
Sbjct: 15 LLLLLGTGLLRASSHVETRAHAEERLLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLI 74
Query: 238 ESESTVRILAD---LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAG 405
+ + +++ ++ W D +L W+ ++ T + + SE +WRPD+VL N A G
Sbjct: 75 DVDEKNQMMTTNVWVKQEWHDYKLRWDPADYENVTSIRIPSELIWRPDIVLYNNAD---G 131
Query: 406 DYAL----RARVSNNGSVSWIKRLDISTPISMQLDXWPNDMQTCTFGFGSXMHNIDXMDF 573
D+A+ +A + ++G V W + S+ + +P D Q CT FGS ++ +D
Sbjct: 132 DFAVTHLTKAHLFHDGRVQWTPPAIYKSSCSIDVTFFPFDQQNCTMKFGSWTYDKAKIDL 191
Query: 574 V 576
V
Sbjct: 192 V 192
>DQ093071-1|AAY88737.1| 627|Homo sapiens cholinergic receptor,
nicotinic, alpha polypeptide 4 protein.
Length = 627
Score = 60.1 bits (139), Expect = 1e-08
Identities = 48/181 (26%), Positives = 89/181 (49%), Gaps = 11/181 (6%)
Frame = +1
Query: 67 LLPFLLTCAIASAAECEN-ATSLSLMIDSLLATYDRESPPDSKI--VVNLTLHLRHANIR 237
LL L T + +++ E A + ++ L + Y++ S P + I VV + L A +
Sbjct: 15 LLLLLGTGLLRASSHVETRAHAEERLLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLI 74
Query: 238 ESESTVRILAD---LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAG 405
+ + +++ ++ W D +L W+ ++ T + + SE +WRPD+VL N A G
Sbjct: 75 DVDEKNQMMTTNVWVKQEWHDYKLRWDPADYENVTSIRIPSELIWRPDIVLYNNAD---G 131
Query: 406 DYAL----RARVSNNGSVSWIKRLDISTPISMQLDXWPNDMQTCTFGFGSXMHNIDXMDF 573
D+A+ +A + ++G V W + S+ + +P D Q CT FGS ++ +D
Sbjct: 132 DFAVTHLTKAHLFHDGRVQWTPPAIYKSSCSIDVTFFPFDQQNCTMKFGSWTYDKAKIDL 191
Query: 574 V 576
V
Sbjct: 192 V 192
>BC101185-1|AAI01186.1| 374|Homo sapiens HTR3E protein protein.
Length = 374
Score = 60.1 bits (139), Expect = 1e-08
Identities = 32/115 (27%), Positives = 57/115 (49%), Gaps = 1/115 (0%)
Frame = +1
Query: 271 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 447
L+M W + +SWN E G + ++++ LW PD+ ++ L A VSN G +
Sbjct: 20 LEMVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEGRI 79
Query: 448 SWIKRLDISTPISMQLDXWPNDMQTCTFGFGSXMHNIDXMDFVIDXEYTVCSXQD 612
+ K + + + ++ + +P D Q CT F S ++ +D M ++D E V D
Sbjct: 80 RYKKPMKVDSICNLDIFYFPFDQQNCTLTFSSFLYTVDSM--LLDMEKEVWEITD 132
>BC101183-1|AAI01184.1| 471|Homo sapiens 5-hydroxytryptamine
(serotonin) receptor 3, family member E protein.
Length = 471
Score = 60.1 bits (139), Expect = 1e-08
Identities = 32/115 (27%), Positives = 57/115 (49%), Gaps = 1/115 (0%)
Frame = +1
Query: 271 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 447
L+M W + +SWN E G + ++++ LW PD+ ++ L A VSN G +
Sbjct: 106 LEMVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEGRI 165
Query: 448 SWIKRLDISTPISMQLDXWPNDMQTCTFGFGSXMHNIDXMDFVIDXEYTVCSXQD 612
+ K + + + ++ + +P D Q CT F S ++ +D M ++D E V D
Sbjct: 166 RYKKPMKVDSICNLDIFYFPFDQQNCTLTFSSFLYTVDSM--LLDMEKEVWEITD 218
>BC101182-1|AAI01183.1| 471|Homo sapiens 5-hydroxytryptamine
(serotonin) receptor 3, family member E protein.
Length = 471
Score = 60.1 bits (139), Expect = 1e-08
Identities = 32/115 (27%), Positives = 57/115 (49%), Gaps = 1/115 (0%)
Frame = +1
Query: 271 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 447
L+M W + +SWN E G + ++++ LW PD+ ++ L A VSN G +
Sbjct: 106 LEMVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEGRI 165
Query: 448 SWIKRLDISTPISMQLDXWPNDMQTCTFGFGSXMHNIDXMDFVIDXEYTVCSXQD 612
+ K + + + ++ + +P D Q CT F S ++ +D M ++D E V D
Sbjct: 166 RYKKPMKVDSICNLDIFYFPFDQQNCTLTFSSFLYTVDSM--LLDMEKEVWEITD 218
>BC096290-1|AAH96290.1| 627|Homo sapiens cholinergic receptor,
nicotinic, alpha 4 protein.
Length = 627
Score = 60.1 bits (139), Expect = 1e-08
Identities = 48/181 (26%), Positives = 89/181 (49%), Gaps = 11/181 (6%)
Frame = +1
Query: 67 LLPFLLTCAIASAAECEN-ATSLSLMIDSLLATYDRESPPDSKI--VVNLTLHLRHANIR 237
LL L T + +++ E A + ++ L + Y++ S P + I VV + L A +
Sbjct: 15 LLLLLGTGLLRASSHVETRAHAEERLLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLI 74
Query: 238 ESESTVRILAD---LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAG 405
+ + +++ ++ W D +L W+ ++ T + + SE +WRPD+VL N A G
Sbjct: 75 DVDEKNQMMTTNVWVKQEWHDYKLRWDPADYENVTSIRIPSELIWRPDIVLYNNAD---G 131
Query: 406 DYAL----RARVSNNGSVSWIKRLDISTPISMQLDXWPNDMQTCTFGFGSXMHNIDXMDF 573
D+A+ +A + ++G V W + S+ + +P D Q CT FGS ++ +D
Sbjct: 132 DFAVTHLTKAHLFHDGRVQWTPPAIYKSSCSIDVTFFPFDQQNCTMKFGSWTYDKAKIDL 191
Query: 574 V 576
V
Sbjct: 192 V 192
>BC023553-1|AAH23553.1| 501|Homo sapiens cholinergic receptor,
nicotinic, beta 1 (muscle) protein.
Length = 501
Score = 60.1 bits (139), Expect = 1e-08
Identities = 43/135 (31%), Positives = 68/135 (50%), Gaps = 6/135 (4%)
Frame = +1
Query: 169 RESPPDSKIVVNLTL-HLRHANIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLV 342
RE ++ V L L L N ++ E + ++ DL+ W D RLSW+ E G + +
Sbjct: 46 REVGDRVRVSVGLILAQLISLNEKDEEMSTKVYLDLE--WTDYRLSWDPAEHDGIDSLRI 103
Query: 343 SSERLWRPDVVLLNAAATTAGDY----ALRARVSNNGSVSWIKRLDISTPISMQLDXWPN 510
++E +W PDVVLLN G++ + VS++GSV W + S+Q+ +P
Sbjct: 104 TAESVWLPDVVLLN---NNDGNFYVALDISVVVSSDGSVRWQPPGIYRSSCSIQVTYFPF 160
Query: 511 DMQTCTFGFGSXMHN 555
D Q CT F S ++
Sbjct: 161 DWQNCTMVFSSYSYD 175
>AY159813-1|AAO38167.2| 471|Homo sapiens 5-hydroxytryptamine
serotonin receptor 3E protein.
Length = 471
Score = 60.1 bits (139), Expect = 1e-08
Identities = 32/115 (27%), Positives = 57/115 (49%), Gaps = 1/115 (0%)
Frame = +1
Query: 271 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 447
L+M W + +SWN E G + ++++ LW PD+ ++ L A VSN G +
Sbjct: 106 LEMVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEGRI 165
Query: 448 SWIKRLDISTPISMQLDXWPNDMQTCTFGFGSXMHNIDXMDFVIDXEYTVCSXQD 612
+ K + + + ++ + +P D Q CT F S ++ +D M ++D E V D
Sbjct: 166 RYKKPMKVDSICNLDIFYFPFDQQNCTLTFSSFLYTVDSM--LLDMEKEVWEITD 218
>X87629-1|CAA60959.1| 602|Homo sapiens nicotinic acetylcholine
receptor protein.
Length = 602
Score = 59.7 bits (138), Expect = 1e-08
Identities = 42/156 (26%), Positives = 78/156 (50%), Gaps = 10/156 (6%)
Frame = +1
Query: 139 MIDSLLATYDRESPPDSKI--VVNLTLHLRHANIRESESTVRILAD---LQMNWIDKRLS 303
++ L + Y++ S P + I VV + L A + + + +++ ++ W D +L
Sbjct: 15 LLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLR 74
Query: 304 WNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNGSVSWIKRLD 468
W+ ++ T + + SE +WRPD+VL N A GD+A+ +A + ++G V W
Sbjct: 75 WDPADYENVTSIRIPSELIWRPDIVLYNNAD---GDFAVTHLTKAHLFHDGRVQWTPPAI 131
Query: 469 ISTPISMQLDXWPNDMQTCTFGFGSXMHNIDXMDFV 576
+ S+ + +P D Q CT FGS ++ +D V
Sbjct: 132 YKSSCSIDVTFFPFDQQNCTMKFGSWTYDKAKIDLV 167
>X01715-1|CAA25861.1| 520|Homo sapiens acetylcholine receptor gamma
chain precursor protein.
Length = 520
Score = 59.7 bits (138), Expect = 1e-08
Identities = 50/184 (27%), Positives = 81/184 (44%), Gaps = 8/184 (4%)
Frame = +1
Query: 61 IILLPFLLTCAIASAAECENATSLSLMIDSLLATYDRESPPDSKI--VVNLTLHLRHANI 234
++LL L C + N L+ D L+ YD P + VVN++L L N+
Sbjct: 8 LLLLLLLAVCLGGTQRNLRNQEE-RLLAD-LMQNYDPNLRPAERDSDVVNVSLKLTLTNL 65
Query: 235 ---RESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTA 402
E E + ++M W D RL W+ ++ G V S +WRPD+VL N
Sbjct: 66 ISLNEREEALTTNVWIEMQWCDYRLRWDPRDYEGLWVLRVPSTMVWRPDIVLENNVDGVF 125
Query: 403 GDYALRARV--SNNGSVSWIKRLDISTPISMQLDXWPNDMQTCTFGFGSXMHNIDXMDFV 576
+ AL V S +G + W+ + S+ + +P D Q C+ F S ++ + +D
Sbjct: 126 -EVALYCNVLVSPDGCIYWLPPAIFRSACSISVTYFPFDWQNCSLIFQSQTYSTNEIDLQ 184
Query: 577 IDXE 588
+ E
Sbjct: 185 LSQE 188
>AC092165-3|AAY24103.1| 520|Homo sapiens unknown protein.
Length = 520
Score = 59.7 bits (138), Expect = 1e-08
Identities = 50/184 (27%), Positives = 81/184 (44%), Gaps = 8/184 (4%)
Frame = +1
Query: 61 IILLPFLLTCAIASAAECENATSLSLMIDSLLATYDRESPPDSKI--VVNLTLHLRHANI 234
++LL L C + N L+ D L+ YD P + VVN++L L N+
Sbjct: 8 LLLLLLLAVCLGGTQRNLRNQEE-RLLAD-LMQNYDPNLRPAERDSDVVNVSLKLTLTNL 65
Query: 235 ---RESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTA 402
E E + ++M W D RL W+ ++ G V S +WRPD+VL N
Sbjct: 66 ISLNEREEALTTNVWIEMQWCDYRLRWDPRDYEGLWVLRVPSTMVWRPDIVLENNVDGVF 125
Query: 403 GDYALRARV--SNNGSVSWIKRLDISTPISMQLDXWPNDMQTCTFGFGSXMHNIDXMDFV 576
+ AL V S +G + W+ + S+ + +P D Q C+ F S ++ + +D
Sbjct: 126 -EVALYCNVLVSPDGCIYWLPPAIFRSACSISVTYFPFDWQNCSLIFQSQTYSTNEIDLQ 184
Query: 577 IDXE 588
+ E
Sbjct: 185 LSQE 188
>X66403-1|CAA47030.1| 493|Homo sapiens acetylcholine receptor
epsilon subunit CHRNE protein.
Length = 493
Score = 59.3 bits (137), Expect = 2e-08
Identities = 35/134 (26%), Positives = 68/134 (50%), Gaps = 3/134 (2%)
Frame = +1
Query: 181 PDSKIVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEWG-CSTWLVSSER 354
P+ + ++L + L + ++ E E T+ + ++W D RL+++ ++G T V SE
Sbjct: 45 PEDTVTISLKVTLTNLISLNEKEETLTTSVWIGIDWQDYRLNYSKDDFGGIETLRVPSEL 104
Query: 355 LWRPDVVLLNAAATTAG-DYALRARVSNNGSVSWIKRLDISTPISMQLDXWPNDMQTCTF 531
+W P++VL N G Y V GSV+W+ + ++++ +P D Q C+
Sbjct: 105 VWLPEIVLENNIDGQFGVAYDANVLVYEGGSVTWLPPAIYRSVCAVEVTYFPFDWQNCSL 164
Query: 532 GFGSXMHNIDXMDF 573
F S +N + ++F
Sbjct: 165 IFRSQTYNAEEVEF 178
>AF105999-1|AAD24503.1| 493|Homo sapiens acetylcholine receptor
epsilon subunit protein.
Length = 493
Score = 59.3 bits (137), Expect = 2e-08
Identities = 35/134 (26%), Positives = 68/134 (50%), Gaps = 3/134 (2%)
Frame = +1
Query: 181 PDSKIVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEWG-CSTWLVSSER 354
P+ + ++L + L + ++ E E T+ + ++W D RL+++ ++G T V SE
Sbjct: 45 PEDTVTISLKVTLTNLISLNEKEETLTTSVWIGIDWQDYRLNYSKDDFGGIETLRVPSEL 104
Query: 355 LWRPDVVLLNAAATTAG-DYALRARVSNNGSVSWIKRLDISTPISMQLDXWPNDMQTCTF 531
+W P++VL N G Y V GSV+W+ + ++++ +P D Q C+
Sbjct: 105 VWLPEIVLENNIDGQFGVAYDANVLVYEGGSVTWLPPAIYRSVCAVEVTYFPFDWQNCSL 164
Query: 532 GFGSXMHNIDXMDF 573
F S +N + ++F
Sbjct: 165 IFRSQTYNAEEVEF 178
>BC131799-1|AAI31800.1| 447|Homo sapiens 5-hydroxytryptamine
(serotonin) receptor 3, family member C protein.
Length = 447
Score = 58.8 bits (136), Expect = 2e-08
Identities = 28/107 (26%), Positives = 55/107 (51%), Gaps = 1/107 (0%)
Frame = +1
Query: 271 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 447
+ + W + ++WN E G + V +E LW PD+ ++ + L A +S+ G +
Sbjct: 91 MDLVWDNPFINWNPKECVGINKLTVLAENLWLPDIFIVESMDVDQTPSGLTAYISSEGRI 150
Query: 448 SWIKRLDISTPISMQLDXWPNDMQTCTFGFGSXMHNIDXMDFVIDXE 588
+ K + +++ ++ + +P D Q CTF F S ++ +D M +D E
Sbjct: 151 KYDKPMRVTSICNLDIFYFPFDQQNCTFTFSSFLYTVDSMLLGMDKE 197
>Y00762-1|CAA68731.1| 457|Homo sapiens protein ( Human mRNA for
muscle acetylcholine receptor alpha-subunit. ).
Length = 457
Score = 58.4 bits (135), Expect = 3e-08
Identities = 43/171 (25%), Positives = 77/171 (45%), Gaps = 10/171 (5%)
Frame = +1
Query: 73 PFLLTCAIASAAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHA---NIR 237
P LL ++ SA + + ++ L Y P D + VV +T+ L+ N+
Sbjct: 5 PLLLLFSLCSAGLVLGSEHETRLVAKLFKDYSSVVRPVEDHRQVVEVTVGLQLIQLINVD 64
Query: 238 ESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYA 414
E V L+ W+D L WN ++G + + SE++WRPD+VL N A GD+A
Sbjct: 65 EVNQIVTTNVRLKQQWVDYNLKWNPDDYGGVKKIHIPSEKIWRPDLVLYNNA---DGDFA 121
Query: 415 L----RARVSNNGSVSWIKRLDISTPISMQLDXWPNDMQTCTFGFGSXMHN 555
+ + + G ++W + + + +P D Q C+ G+ ++
Sbjct: 122 IVKFTKVLLQYTGHITWTPPAIFKSYCEIIVTHFPFDEQNCSMKLGTWTYD 172
>X02502-1|CAA26344.1| 457|Homo sapiens acetylcholine receptor
protein.
Length = 457
Score = 58.4 bits (135), Expect = 3e-08
Identities = 43/171 (25%), Positives = 77/171 (45%), Gaps = 10/171 (5%)
Frame = +1
Query: 73 PFLLTCAIASAAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHA---NIR 237
P LL ++ SA + + ++ L Y P D + VV +T+ L+ N+
Sbjct: 5 PLLLLFSLCSAGLVLGSEHETRLVAKLFKDYSSVVRPVEDHRQVVEVTVGLQLIQLINVD 64
Query: 238 ESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYA 414
E V L+ W+D L WN ++G + + SE++WRPD+VL N A GD+A
Sbjct: 65 EVNQIVTTNVRLKQQWVDYNLKWNPDDYGGVKKIHIPSEKIWRPDLVLYNNA---DGDFA 121
Query: 415 L----RARVSNNGSVSWIKRLDISTPISMQLDXWPNDMQTCTFGFGSXMHN 555
+ + + G ++W + + + +P D Q C+ G+ ++
Sbjct: 122 IVKFTKVLLQYTGHITWTPPAIFKSYCEIIVTHFPFDEQNCSMKLGTWTYD 172
>S77094-1|AAD14247.1| 457|Homo sapiens nicotinic acetylcholine
receptor alpha subunit|AChR protein.
Length = 457
Score = 58.4 bits (135), Expect = 3e-08
Identities = 43/171 (25%), Positives = 77/171 (45%), Gaps = 10/171 (5%)
Frame = +1
Query: 73 PFLLTCAIASAAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHA---NIR 237
P LL ++ SA + + ++ L Y P D + VV +T+ L+ N+
Sbjct: 5 PLLLLFSLCSAGLVLGSEHETRLVAKLFKDYSSVVRPVEDHRQVVEVTVGLQLIQLINVD 64
Query: 238 ESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYA 414
E V L+ W+D L WN ++G + + SE++WRPD+VL N A GD+A
Sbjct: 65 EVNQIVTTNVRLKQQWVDYNLKWNPDDYGGVKKIHIPSEKIWRPDLVLYNNA---DGDFA 121
Query: 415 L----RARVSNNGSVSWIKRLDISTPISMQLDXWPNDMQTCTFGFGSXMHN 555
+ + + G ++W + + + +P D Q C+ G+ ++
Sbjct: 122 IVKFTKVLLQYTGHITWTPPAIFKSYCEIIVTHFPFDEQNCSMKLGTWTYD 172
>BC006314-1|AAH06314.1| 269|Homo sapiens CHRNA1 protein protein.
Length = 269
Score = 58.4 bits (135), Expect = 3e-08
Identities = 43/171 (25%), Positives = 77/171 (45%), Gaps = 10/171 (5%)
Frame = +1
Query: 73 PFLLTCAIASAAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHA---NIR 237
P LL ++ SA + + ++ L Y P D + VV +T+ L+ N+
Sbjct: 5 PLLLLFSLCSAGLVLGSEHETRLVAKLFKDYSSVVRPVEDHRQVVEVTVGLQLIQLINVD 64
Query: 238 ESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYA 414
E V L+ W+D L WN ++G + + SE++WRPD+VL N A GD+A
Sbjct: 65 EVNQIVTTNVRLKQQWVDYNLKWNPDDYGGVKKIHIPSEKIWRPDLVLYNNA---DGDFA 121
Query: 415 L----RARVSNNGSVSWIKRLDISTPISMQLDXWPNDMQTCTFGFGSXMHN 555
+ + + G ++W + + + +P D Q C+ G+ ++
Sbjct: 122 IVKFTKVLLQYTGHITWTPPAIFKSYCEIIVTHFPFDEQNCSMKLGTWTYD 172
>AF459285-1|AAL66182.1| 447|Homo sapiens 5-hydroxytryptamine
receptor 3 subunit C protein.
Length = 447
Score = 58.4 bits (135), Expect = 3e-08
Identities = 28/107 (26%), Positives = 54/107 (50%), Gaps = 1/107 (0%)
Frame = +1
Query: 271 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 447
+ + W + ++WN E G + V +E LW PD+ ++ + L A +S+ G +
Sbjct: 91 MDLVWDNPFINWNPKECVGINKLTVLAENLWLPDIFIVESMDVDQTPSGLTAYISSEGRI 150
Query: 448 SWIKRLDISTPISMQLDXWPNDMQTCTFGFGSXMHNIDXMDFVIDXE 588
+ K + +++ + + +P D Q CTF F S ++ +D M +D E
Sbjct: 151 KYDKPMRVTSICKLDIFYFPFDQQNCTFTFSSFLYTVDSMLLGMDKE 197
>AC018890-1|AAY14687.1| 457|Homo sapiens unknown protein.
Length = 457
Score = 58.4 bits (135), Expect = 3e-08
Identities = 43/171 (25%), Positives = 77/171 (45%), Gaps = 10/171 (5%)
Frame = +1
Query: 73 PFLLTCAIASAAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHA---NIR 237
P LL ++ SA + + ++ L Y P D + VV +T+ L+ N+
Sbjct: 5 PLLLLFSLCSAGLVLGSEHETRLVAKLFKDYSSVVRPVEDHRQVVEVTVGLQLIQLINVD 64
Query: 238 ESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYA 414
E V L+ W+D L WN ++G + + SE++WRPD+VL N A GD+A
Sbjct: 65 EVNQIVTTNVRLKQQWVDYNLKWNPDDYGGVKKIHIPSEKIWRPDLVLYNNA---DGDFA 121
Query: 415 L----RARVSNNGSVSWIKRLDISTPISMQLDXWPNDMQTCTFGFGSXMHN 555
+ + + G ++W + + + +P D Q C+ G+ ++
Sbjct: 122 IVKFTKVLLQYTGHITWTPPAIFKSYCEIIVTHFPFDEQNCSMKLGTWTYD 172
>AY349353-1|AAQ93477.1| 456|Homo sapiens 5-HT3c1 serotonin
receptor-like protein protein.
Length = 456
Score = 58.0 bits (134), Expect = 4e-08
Identities = 32/117 (27%), Positives = 57/117 (48%), Gaps = 1/117 (0%)
Frame = +1
Query: 265 ADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNG 441
A L + W + +SWN E G + ++++ LW PD+ ++ L A VSN G
Sbjct: 89 AILDVVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEG 148
Query: 442 SVSWIKRLDISTPISMQLDXWPNDMQTCTFGFGSXMHNIDXMDFVIDXEYTVCSXQD 612
+ + K + + + ++ + +P D Q CT F S ++ +D M ++D E V D
Sbjct: 149 RIRYKKPMKVDSICNLDIFYFPFDQQNCTLTFSSFLYTVDSM--LLDMEKEVWEITD 203
>AY349352-1|AAQ93476.1| 441|Homo sapiens 5-HT3c1 serotonin
receptor-like protein protein.
Length = 441
Score = 58.0 bits (134), Expect = 4e-08
Identities = 32/117 (27%), Positives = 57/117 (48%), Gaps = 1/117 (0%)
Frame = +1
Query: 265 ADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNG 441
A L + W + +SWN E G + ++++ LW PD+ ++ L A VSN G
Sbjct: 74 AILDVVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEG 133
Query: 442 SVSWIKRLDISTPISMQLDXWPNDMQTCTFGFGSXMHNIDXMDFVIDXEYTVCSXQD 612
+ + K + + + ++ + +P D Q CT F S ++ +D M ++D E V D
Sbjct: 134 RIRYKKPMKVDSICNLDIFYFPFDQQNCTLTFSSFLYTVDSM--LLDMEKEVWEITD 188
>AJ295237-1|CAC16144.1| 450|Homo sapiens neuronal nicotinic
acetylcholine receptor subunit4 protein.
Length = 450
Score = 57.6 bits (133), Expect = 6e-08
Identities = 48/176 (27%), Positives = 76/176 (43%), Gaps = 7/176 (3%)
Frame = +1
Query: 64 ILLPFLLTCAIASAAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHANIR 237
+LL FLL A E +L L D L A Y P D+ +N+TL + + I
Sbjct: 12 LLLLFLLPAECLGA---EGRLALKLFRD-LFANYTSALRPVADTDQTLNVTLEVTLSQII 67
Query: 238 ESESTVRILAD---LQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLLNAA-ATTA 402
+ + ++L ++ W D L W+ +G + S +WRPD+VL N A A
Sbjct: 68 DMDERNQVLTLYLWIRQEWTDAYLRWDPNAYGGLDAIRIPSSLVWRPDIVLYNKADAQPP 127
Query: 403 GDYALRARVSNNGSVSWIKRLDISTPISMQLDXWPNDMQTCTFGFGSXMHNIDXMD 570
G + + ++G+V W + + + +P D Q C FGS H +D
Sbjct: 128 GSASTNVVLRHDGAVRWDAPAITRSSCRVDVAAFPFDAQHCGLTFGSWTHGGHQLD 183
>AJ278118-1|CAC20435.1| 450|Homo sapiens neuronal nicotinic
acetylcholine alpha10 subunit protein.
Length = 450
Score = 57.6 bits (133), Expect = 6e-08
Identities = 48/176 (27%), Positives = 76/176 (43%), Gaps = 7/176 (3%)
Frame = +1
Query: 64 ILLPFLLTCAIASAAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHANIR 237
+LL FLL A E +L L D L A Y P D+ +N+TL + + I
Sbjct: 12 LLLLFLLPAECLGA---EGRLALKLFRD-LFANYTSALRPVADTDQTLNVTLEVTLSQII 67
Query: 238 ESESTVRILAD---LQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLLNAA-ATTA 402
+ + ++L ++ W D L W+ +G + S +WRPD+VL N A A
Sbjct: 68 DMDERNQVLTLYLWIRQEWTDAYLRWDPNAYGGLDAIRIPSSLVWRPDIVLYNKADAQPP 127
Query: 403 GDYALRARVSNNGSVSWIKRLDISTPISMQLDXWPNDMQTCTFGFGSXMHNIDXMD 570
G + + ++G+V W + + + +P D Q C FGS H +D
Sbjct: 128 GSASTNVVLRHDGAVRWDAPAITRSSCRVDVAAFPFDAQHCGLTFGSWTHGGHQLD 183
>AF327367-1|AAK14333.1| 450|Homo sapiens nicotinic acetylcholine
receptor subunit alpha 10 protein.
Length = 450
Score = 57.6 bits (133), Expect = 6e-08
Identities = 48/176 (27%), Positives = 76/176 (43%), Gaps = 7/176 (3%)
Frame = +1
Query: 64 ILLPFLLTCAIASAAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHANIR 237
+LL FLL A E +L L D L A Y P D+ +N+TL + + I
Sbjct: 12 LLLLFLLPAECLGA---EGRLALKLFRD-LFANYTSALRPVADTDQTLNVTLEVTLSQII 67
Query: 238 ESESTVRILAD---LQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLLNAA-ATTA 402
+ + ++L ++ W D L W+ +G + S +WRPD+VL N A A
Sbjct: 68 DMDERNQVLTLYLWIRQEWTDAYLRWDPNAYGGLDAIRIPSSLVWRPDIVLYNKADAQPP 127
Query: 403 GDYALRARVSNNGSVSWIKRLDISTPISMQLDXWPNDMQTCTFGFGSXMHNIDXMD 570
G + + ++G+V W + + + +P D Q C FGS H +D
Sbjct: 128 GSASTNVVLRHDGAVRWDAPAITRSSCRVDVAAFPFDAQHCGLTFGSWTHGGHQLD 183
>AF199235-1|AAG00795.2| 450|Homo sapiens nicotinic acetylcholine
receptor subunit alpha 10 protein.
Length = 450
Score = 57.6 bits (133), Expect = 6e-08
Identities = 48/176 (27%), Positives = 76/176 (43%), Gaps = 7/176 (3%)
Frame = +1
Query: 64 ILLPFLLTCAIASAAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHANIR 237
+LL FLL A E +L L D L A Y P D+ +N+TL + + I
Sbjct: 12 LLLLFLLPAECLGA---EGRLALKLFRD-LFANYTSALRPVADTDQTLNVTLEVTLSQII 67
Query: 238 ESESTVRILAD---LQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLLNAA-ATTA 402
+ + ++L ++ W D L W+ +G + S +WRPD+VL N A A
Sbjct: 68 DMDERNQVLTLYLWIRQEWTDAYLRWDPNAYGGLDAIRIPSSLVWRPDIVLYNKADAQPP 127
Query: 403 GDYALRARVSNNGSVSWIKRLDISTPISMQLDXWPNDMQTCTFGFGSXMHNIDXMD 570
G + + ++G+V W + + + +P D Q C FGS H +D
Sbjct: 128 GSASTNVVLRHDGAVRWDAPAITRSSCRVDVAAFPFDAQHCGLTFGSWTHGGHQLD 183
>BC113575-1|AAI13576.1| 479|Homo sapiens cholinergic receptor,
nicotinic, alpha 9 protein.
Length = 479
Score = 57.2 bits (132), Expect = 7e-08
Identities = 39/163 (23%), Positives = 75/163 (46%), Gaps = 7/163 (4%)
Frame = +1
Query: 103 AAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHANIRESESTVRILAD-- 270
AAE + + + L Y P D+ V+N+TL + + I++ + +IL
Sbjct: 22 AAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQITLSQIKDMDERNQILTAYL 81
Query: 271 -LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGD-YALRARVSNNG 441
++ W D L+W+ ++ G + + S+ +WRPD+VL N A + + + +G
Sbjct: 82 WIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKADDESSEPVNTNVVLRYDG 141
Query: 442 SVSWIKRLDISTPISMQLDXWPNDMQTCTFGFGSXMHNIDXMD 570
++W + + + +P D Q C FGS +N + +D
Sbjct: 142 LITWDAPAITKSSCVVDVTYFPFDNQQCNLTFGSWTYNGNQVD 184
>BC113549-1|AAI13550.1| 479|Homo sapiens cholinergic receptor,
nicotinic, alpha 9 protein.
Length = 479
Score = 57.2 bits (132), Expect = 7e-08
Identities = 39/163 (23%), Positives = 75/163 (46%), Gaps = 7/163 (4%)
Frame = +1
Query: 103 AAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHANIRESESTVRILAD-- 270
AAE + + + L Y P D+ V+N+TL + + I++ + +IL
Sbjct: 22 AAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQITLSQIKDMDERNQILTAYL 81
Query: 271 -LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGD-YALRARVSNNG 441
++ W D L+W+ ++ G + + S+ +WRPD+VL N A + + + +G
Sbjct: 82 WIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKADDESSEPVNTNVVLRYDG 141
Query: 442 SVSWIKRLDISTPISMQLDXWPNDMQTCTFGFGSXMHNIDXMD 570
++W + + + +P D Q C FGS +N + +D
Sbjct: 142 LITWDAPAITKSSCVVDVTYFPFDNQQCNLTFGSWTYNGNQVD 184
>AY123244-1|AAM74523.1| 479|Homo sapiens nicotinic acetylcholine
receptor subunit alpha 9 protein.
Length = 479
Score = 57.2 bits (132), Expect = 7e-08
Identities = 39/163 (23%), Positives = 75/163 (46%), Gaps = 7/163 (4%)
Frame = +1
Query: 103 AAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHANIRESESTVRILAD-- 270
AAE + + + L Y P D+ V+N+TL + + I++ + +IL
Sbjct: 22 AAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQITLSQIKDMDERNQILTAYL 81
Query: 271 -LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGD-YALRARVSNNG 441
++ W D L+W+ ++ G + + S+ +WRPD+VL N A + + + +G
Sbjct: 82 WIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKADDESSEPVNTNVVLRYDG 141
Query: 442 SVSWIKRLDISTPISMQLDXWPNDMQTCTFGFGSXMHNIDXMD 570
++W + + + +P D Q C FGS +N + +D
Sbjct: 142 LITWDAPAITKSSCVVDVTYFPFDNQQCNLTFGSWTYNGNQVD 184
>AJ243342-1|CAB65091.1| 479|Homo sapiens nicotinic acetylcholine
receptor alpha 9 subunit protein.
Length = 479
Score = 57.2 bits (132), Expect = 7e-08
Identities = 39/163 (23%), Positives = 75/163 (46%), Gaps = 7/163 (4%)
Frame = +1
Query: 103 AAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHANIRESESTVRILAD-- 270
AAE + + + L Y P D+ V+N+TL + + I++ + +IL
Sbjct: 22 AAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQITLSQIKDMDERNQILTAYL 81
Query: 271 -LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGD-YALRARVSNNG 441
++ W D L+W+ ++ G + + S+ +WRPD+VL N A + + + +G
Sbjct: 82 WIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKADDESSEPVNTNVVLRYDG 141
Query: 442 SVSWIKRLDISTPISMQLDXWPNDMQTCTFGFGSXMHNIDXMD 570
++W + + + +P D Q C FGS +N + +D
Sbjct: 142 LITWDAPAITKSSCVVDVTYFPFDNQQCNLTFGSWTYNGNQVD 184
>AF227732-1|AAF61920.1| 470|Homo sapiens nicotinic acetylcholine
receptor alpha 9 subunit protein.
Length = 470
Score = 57.2 bits (132), Expect = 7e-08
Identities = 39/163 (23%), Positives = 75/163 (46%), Gaps = 7/163 (4%)
Frame = +1
Query: 103 AAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHANIRESESTVRILAD-- 270
AAE + + + L Y P D+ V+N+TL + + I++ + +IL
Sbjct: 16 AAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQITLSQIKDMDERNQILTAYL 75
Query: 271 -LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGD-YALRARVSNNG 441
++ W D L+W+ ++ G + + S+ +WRPD+VL N A + + + +G
Sbjct: 76 WIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKADDESSEPVNTNVVLRYDG 135
Query: 442 SVSWIKRLDISTPISMQLDXWPNDMQTCTFGFGSXMHNIDXMD 570
++W + + + +P D Q C FGS +N + +D
Sbjct: 136 LITWDAPAITKSSCVVDVTYFPFDNQQCNLTFGSWTYNGNQVD 178
>AC118275-1|AAY40986.1| 479|Homo sapiens unknown protein.
Length = 479
Score = 57.2 bits (132), Expect = 7e-08
Identities = 39/163 (23%), Positives = 75/163 (46%), Gaps = 7/163 (4%)
Frame = +1
Query: 103 AAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHANIRESESTVRILAD-- 270
AAE + + + L Y P D+ V+N+TL + + I++ + +IL
Sbjct: 22 AAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQITLSQIKDMDERNQILTAYL 81
Query: 271 -LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGD-YALRARVSNNG 441
++ W D L+W+ ++ G + + S+ +WRPD+VL N A + + + +G
Sbjct: 82 WIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKADDESSEPVNTNVVLRYDG 141
Query: 442 SVSWIKRLDISTPISMQLDXWPNDMQTCTFGFGSXMHNIDXMD 570
++W + + + +P D Q C FGS +N + +D
Sbjct: 142 LITWDAPAITKSSCVVDVTYFPFDNQQCNLTFGSWTYNGNQVD 184
>AJ001935-1|CAA05108.1| 504|Homo sapiens CHRNB2 protein.
Length = 504
Score = 56.0 bits (129), Expect = 2e-07
Identities = 49/181 (27%), Positives = 78/181 (43%), Gaps = 6/181 (3%)
Frame = +1
Query: 64 ILLPF--LLTCAIASAAECENATSLSLMIDSLLATYDRESPPDSKIV-VNLTLHLRHA-N 231
+LL F L C+ A+ E L+ S R + S++V V L + L +
Sbjct: 10 LLLGFGLLRLCSGVWGADTEERLVEHLLDPSRYNKLIRPATNGSELVTVQLMVSLAQLIS 69
Query: 232 IRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAG 405
+ E E + L W D RL+W E+ + S+ +W PDVVL N A
Sbjct: 70 VHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLPDVVLYNNADGMYEV 129
Query: 406 DYALRARVSNNGSVSWIKRLDISTPISMQLDXWPNDMQTCTFGFGSXMHNIDXMDFVIDX 585
+ A VS +GS+ W+ + +++ +P D Q CT F S ++ +D V+
Sbjct: 130 SFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRSWTYDRTEIDLVLKS 189
Query: 586 E 588
E
Sbjct: 190 E 190
>Y08415-1|CAA69692.1| 502|Homo sapiens nicotinic acetylcholine
receptor beta2 subunit precursor protein.
Length = 502
Score = 55.6 bits (128), Expect = 2e-07
Identities = 37/135 (27%), Positives = 60/135 (44%), Gaps = 3/135 (2%)
Frame = +1
Query: 193 IVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 366
+ V L + L ++ E E + L W D RL+W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 367 DVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDXWPNDMQTCTFGFGS 543
DVVL N A + A VS +GS+ W+ + +++ +P D Q CT F S
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRS 175
Query: 544 XMHNIDXMDFVIDXE 588
++ +D V+ E
Sbjct: 176 WTYDRTEIDLVLKSE 190
>X53179-1|CAA37320.1| 502|Homo sapiens precursor peptide (AA -25 to
477) protein.
Length = 502
Score = 55.6 bits (128), Expect = 2e-07
Identities = 37/135 (27%), Positives = 60/135 (44%), Gaps = 3/135 (2%)
Frame = +1
Query: 193 IVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 366
+ V L + L ++ E E + L W D RL+W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 367 DVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDXWPNDMQTCTFGFGS 543
DVVL N A + A VS +GS+ W+ + +++ +P D Q CT F S
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRS 175
Query: 544 XMHNIDXMDFVIDXE 588
++ +D V+ E
Sbjct: 176 WTYDRTEIDLVLKSE 190
>U62437-1|AAB40115.1| 502|Homo sapiens nicotinic acetylcholine
receptor beta2 subunit precursor protein.
Length = 502
Score = 55.6 bits (128), Expect = 2e-07
Identities = 37/135 (27%), Positives = 60/135 (44%), Gaps = 3/135 (2%)
Frame = +1
Query: 193 IVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 366
+ V L + L ++ E E + L W D RL+W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 367 DVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDXWPNDMQTCTFGFGS 543
DVVL N A + A VS +GS+ W+ + +++ +P D Q CT F S
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRS 175
Query: 544 XMHNIDXMDFVIDXE 588
++ +D V+ E
Sbjct: 176 WTYDRTEIDLVLKSE 190
>BC075041-1|AAH75041.1| 502|Homo sapiens cholinergic receptor,
nicotinic, beta 2 (neuronal) protein.
Length = 502
Score = 55.6 bits (128), Expect = 2e-07
Identities = 37/135 (27%), Positives = 60/135 (44%), Gaps = 3/135 (2%)
Frame = +1
Query: 193 IVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 366
+ V L + L ++ E E + L W D RL+W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 367 DVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDXWPNDMQTCTFGFGS 543
DVVL N A + A VS +GS+ W+ + +++ +P D Q CT F S
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRS 175
Query: 544 XMHNIDXMDFVIDXE 588
++ +D V+ E
Sbjct: 176 WTYDRTEIDLVLKSE 190
>BC075040-1|AAH75040.1| 502|Homo sapiens cholinergic receptor,
nicotinic, beta 2 (neuronal) protein.
Length = 502
Score = 55.6 bits (128), Expect = 2e-07
Identities = 37/135 (27%), Positives = 60/135 (44%), Gaps = 3/135 (2%)
Frame = +1
Query: 193 IVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 366
+ V L + L ++ E E + L W D RL+W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 367 DVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDXWPNDMQTCTFGFGS 543
DVVL N A + A VS +GS+ W+ + +++ +P D Q CT F S
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRS 175
Query: 544 XMHNIDXMDFVIDXE 588
++ +D V+ E
Sbjct: 176 WTYDRTEIDLVLKSE 190
>AL592078-3|CAI16184.1| 502|Homo sapiens cholinergic receptor,
nicotinic, beta 2 (neuronal) protein.
Length = 502
Score = 55.6 bits (128), Expect = 2e-07
Identities = 37/135 (27%), Positives = 60/135 (44%), Gaps = 3/135 (2%)
Frame = +1
Query: 193 IVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 366
+ V L + L ++ E E + L W D RL+W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 367 DVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDXWPNDMQTCTFGFGS 543
DVVL N A + A VS +GS+ W+ + +++ +P D Q CT F S
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRS 175
Query: 544 XMHNIDXMDFVIDXE 588
++ +D V+ E
Sbjct: 176 WTYDRTEIDLVLKSE 190
>AF077186-1|AAD45422.1| 502|Homo sapiens neuronal nicotinic
acetylcholine receptor beta 2 protein.
Length = 502
Score = 55.6 bits (128), Expect = 2e-07
Identities = 37/135 (27%), Positives = 60/135 (44%), Gaps = 3/135 (2%)
Frame = +1
Query: 193 IVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 366
+ V L + L ++ E E + L W D RL+W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 367 DVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDXWPNDMQTCTFGFGS 543
DVVL N A + A VS +GS+ W+ + +++ +P D Q CT F S
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRS 175
Query: 544 XMHNIDXMDFVIDXE 588
++ +D V+ E
Sbjct: 176 WTYDRTEIDLVLKSE 190
>BC111802-1|AAI11803.1| 465|Homo sapiens CHRNG protein protein.
Length = 465
Score = 53.2 bits (122), Expect = 1e-06
Identities = 37/135 (27%), Positives = 60/135 (44%), Gaps = 7/135 (5%)
Frame = +1
Query: 73 PFLLTCAIASAAECENATSLSLMIDSLLATYDRESPPDSKI--VVNLTLHLRHANI---R 237
P LL +A + ++ L+ YD P + VVN++L L N+
Sbjct: 7 PLLLLLLLAVCLGAQGRNQEERLLADLMQNYDPNLRPAERDSDVVNVSLKLTLTNLISLN 66
Query: 238 ESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAAT-TAGDY 411
E E + ++M W D RL W+ ++ G V S +WRPD+VL N + T + +
Sbjct: 67 EREEALTTNVWIEMQWCDYRLRWDPRDYEGLWVLRVPSTMVWRPDIVLENKSQTYSTNEI 126
Query: 412 ALRARVSNNGSVSWI 456
L+ + S+ WI
Sbjct: 127 DLQLSQEDGQSIEWI 141
>X55019-1|CAA38759.1| 517|Homo sapiens acetylcholine receptor delta
subunit protein.
Length = 517
Score = 52.0 bits (119), Expect = 3e-06
Identities = 36/134 (26%), Positives = 62/134 (46%), Gaps = 7/134 (5%)
Frame = +1
Query: 163 YDRESPP----DSKIVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEWG- 324
Y++E P + + V L L L + +++E E T+ ++ W D RL WNA E+G
Sbjct: 38 YNKELRPVAHKEESVDVALALTLSNLISLKEVEETLTTNVWIEHGWTDNRLKWNAEEFGN 97
Query: 325 CSTWLVSSERLWRPDVVL-LNAAATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDX 501
S + + +W P++VL N + Y+ V + G V W+ + + +
Sbjct: 98 ISVLRLPPDMVWLPEIVLENNNDGSFQISYSCNVLVYHYGFVYWLPPAIFRSSCPISVTY 157
Query: 502 WPNDMQTCTFGFGS 543
+P D Q C+ F S
Sbjct: 158 FPFDWQNCSLKFSS 171
>BC093925-1|AAH93925.1| 517|Homo sapiens cholinergic receptor,
nicotinic, delta protein.
Length = 517
Score = 52.0 bits (119), Expect = 3e-06
Identities = 36/134 (26%), Positives = 62/134 (46%), Gaps = 7/134 (5%)
Frame = +1
Query: 163 YDRESPP----DSKIVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEWG- 324
Y++E P + + V L L L + +++E E T+ ++ W D RL WNA E+G
Sbjct: 38 YNKELRPVAHKEESVDVALALTLSNLISLKEVEETLTTNVWIEHGWTDNRLKWNAEEFGN 97
Query: 325 CSTWLVSSERLWRPDVVL-LNAAATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDX 501
S + + +W P++VL N + Y+ V + G V W+ + + +
Sbjct: 98 ISVLRLPPDMVWLPEIVLENNNDGSFQISYSCNVLVYHYGFVYWLPPAIFRSSCPISVTY 157
Query: 502 WPNDMQTCTFGFGS 543
+P D Q C+ F S
Sbjct: 158 FPFDWQNCSLKFSS 171
>BC093923-1|AAH93923.1| 517|Homo sapiens cholinergic receptor,
nicotinic, delta protein.
Length = 517
Score = 52.0 bits (119), Expect = 3e-06
Identities = 36/134 (26%), Positives = 62/134 (46%), Gaps = 7/134 (5%)
Frame = +1
Query: 163 YDRESPP----DSKIVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEWG- 324
Y++E P + + V L L L + +++E E T+ ++ W D RL WNA E+G
Sbjct: 38 YNKELRPVAHKEESVDVALALTLSNLISLKEVEETLTTNVWIEHGWTDNRLKWNAEEFGN 97
Query: 325 CSTWLVSSERLWRPDVVL-LNAAATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDX 501
S + + +W P++VL N + Y+ V + G V W+ + + +
Sbjct: 98 ISVLRLPPDMVWLPEIVLENNNDGSFQISYSCNVLVYHYGFVYWLPPAIFRSSCPISVTY 157
Query: 502 WPNDMQTCTFGFGS 543
+P D Q C+ F S
Sbjct: 158 FPFDWQNCSLKFSS 171
>AC092165-2|AAY24102.1| 517|Homo sapiens unknown protein.
Length = 517
Score = 52.0 bits (119), Expect = 3e-06
Identities = 36/134 (26%), Positives = 62/134 (46%), Gaps = 7/134 (5%)
Frame = +1
Query: 163 YDRESPP----DSKIVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEWG- 324
Y++E P + + V L L L + +++E E T+ ++ W D RL WNA E+G
Sbjct: 38 YNKELRPVAHKEESVDVALALTLSNLISLKEVEETLTTNVWIEHGWTDNRLKWNAEEFGN 97
Query: 325 CSTWLVSSERLWRPDVVL-LNAAATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDX 501
S + + +W P++VL N + Y+ V + G V W+ + + +
Sbjct: 98 ISVLRLPPDMVWLPEIVLENNNDGSFQISYSCNVLVYHYGFVYWLPPAIFRSSCPISVTY 157
Query: 502 WPNDMQTCTFGFGS 543
+P D Q C+ F S
Sbjct: 158 FPFDWQNCSLKFSS 171
>S77554-1|AAB33983.1| 474|Homo sapiens GABAA receptor beta 2
subunit protein.
Length = 474
Score = 51.6 bits (118), Expect = 4e-06
Identities = 44/182 (24%), Positives = 76/182 (41%), Gaps = 10/182 (5%)
Frame = +1
Query: 58 YIILLPFLLTCAIASAAECENATSLSLM---IDSLLATYDRESPPD---SKIVVNLTLHL 219
Y + F L A A + +++SL+ +D LL YD PD + V + + +
Sbjct: 9 YFGIWSFPLIIAAVCAQSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDI 68
Query: 220 RHAN-IRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAAT 396
+ + E + Q W DKRLS+N + +++LW PD LN +
Sbjct: 69 ASIDMVSEVNMDYTLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLNDKKS 128
Query: 397 TAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDXWPNDMQTCTFGFGSXMHNIDXM 567
++ R+ +G+V + R+ + M L +P D Q CT S + D +
Sbjct: 129 FVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDI 188
Query: 568 DF 573
+F
Sbjct: 189 EF 190
>S77553-1|AAB33982.1| 512|Homo sapiens GABAA receptor beta 2
subunit protein.
Length = 512
Score = 51.6 bits (118), Expect = 4e-06
Identities = 44/182 (24%), Positives = 76/182 (41%), Gaps = 10/182 (5%)
Frame = +1
Query: 58 YIILLPFLLTCAIASAAECENATSLSLM---IDSLLATYDRESPPD---SKIVVNLTLHL 219
Y + F L A A + +++SL+ +D LL YD PD + V + + +
Sbjct: 9 YFGIWSFPLIIAAVCAQSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDI 68
Query: 220 RHAN-IRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAAT 396
+ + E + Q W DKRLS+N + +++LW PD LN +
Sbjct: 69 ASIDMVSEVNMDYTLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLNDKKS 128
Query: 397 TAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDXWPNDMQTCTFGFGSXMHNIDXM 567
++ R+ +G+V + R+ + M L +P D Q CT S + D +
Sbjct: 129 FVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDI 188
Query: 568 DF 573
+F
Sbjct: 189 EF 190
>S67368-1|AAB29370.1| 474|Homo sapiens gamma-aminobutyric acid A
receptor beta 2 subunit protein.
Length = 474
Score = 51.6 bits (118), Expect = 4e-06
Identities = 44/182 (24%), Positives = 76/182 (41%), Gaps = 10/182 (5%)
Frame = +1
Query: 58 YIILLPFLLTCAIASAAECENATSLSLM---IDSLLATYDRESPPD---SKIVVNLTLHL 219
Y + F L A A + +++SL+ +D LL YD PD + V + + +
Sbjct: 9 YFGIWSFPLIIAAVCAQSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDI 68
Query: 220 RHAN-IRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAAT 396
+ + E + Q W DKRLS+N + +++LW PD LN +
Sbjct: 69 ASIDMVSEVNMDYTLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLNDKKS 128
Query: 397 TAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDXWPNDMQTCTFGFGSXMHNIDXM 567
++ R+ +G+V + R+ + M L +P D Q CT S + D +
Sbjct: 129 FVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDI 188
Query: 568 DF 573
+F
Sbjct: 189 EF 190
>BC105639-1|AAI05640.1| 474|Homo sapiens GABRB2 protein protein.
Length = 474
Score = 51.6 bits (118), Expect = 4e-06
Identities = 44/182 (24%), Positives = 76/182 (41%), Gaps = 10/182 (5%)
Frame = +1
Query: 58 YIILLPFLLTCAIASAAECENATSLSLM---IDSLLATYDRESPPD---SKIVVNLTLHL 219
Y + F L A A + +++SL+ +D LL YD PD + V + + +
Sbjct: 9 YFGIWSFPLIIAAVCAQSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDI 68
Query: 220 RHAN-IRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAAT 396
+ + E + Q W DKRLS+N + +++LW PD LN +
Sbjct: 69 ASIDMVSEVNMDYTLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLNDKKS 128
Query: 397 TAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDXWPNDMQTCTFGFGSXMHNIDXM 567
++ R+ +G+V + R+ + M L +P D Q CT S + D +
Sbjct: 129 FVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDI 188
Query: 568 DF 573
+F
Sbjct: 189 EF 190
>BC099719-1|AAH99719.1| 474|Homo sapiens GABRB2 protein protein.
Length = 474
Score = 51.6 bits (118), Expect = 4e-06
Identities = 44/182 (24%), Positives = 76/182 (41%), Gaps = 10/182 (5%)
Frame = +1
Query: 58 YIILLPFLLTCAIASAAECENATSLSLM---IDSLLATYDRESPPD---SKIVVNLTLHL 219
Y + F L A A + +++SL+ +D LL YD PD + V + + +
Sbjct: 9 YFGIWSFPLIIAAVCAQSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDI 68
Query: 220 RHAN-IRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAAT 396
+ + E + Q W DKRLS+N + +++LW PD LN +
Sbjct: 69 ASIDMVSEVNMDYTLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLNDKKS 128
Query: 397 TAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDXWPNDMQTCTFGFGSXMHNIDXM 567
++ R+ +G+V + R+ + M L +P D Q CT S + D +
Sbjct: 129 FVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDI 188
Query: 568 DF 573
+F
Sbjct: 189 EF 190
>BC099705-1|AAH99705.1| 474|Homo sapiens GABRB2 protein protein.
Length = 474
Score = 51.6 bits (118), Expect = 4e-06
Identities = 44/182 (24%), Positives = 76/182 (41%), Gaps = 10/182 (5%)
Frame = +1
Query: 58 YIILLPFLLTCAIASAAECENATSLSLM---IDSLLATYDRESPPD---SKIVVNLTLHL 219
Y + F L A A + +++SL+ +D LL YD PD + V + + +
Sbjct: 9 YFGIWSFPLIIAAVCAQSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDI 68
Query: 220 RHAN-IRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAAT 396
+ + E + Q W DKRLS+N + +++LW PD LN +
Sbjct: 69 ASIDMVSEVNMDYTLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLNDKKS 128
Query: 397 TAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDXWPNDMQTCTFGFGSXMHNIDXM 567
++ R+ +G+V + R+ + M L +P D Q CT S + D +
Sbjct: 129 FVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDI 188
Query: 568 DF 573
+F
Sbjct: 189 EF 190
>S82612-1|AAB37533.2| 478|Homo sapiens 5-hydroxytryptamine type 3AS
receptor subunit protein.
Length = 478
Score = 51.2 bits (117), Expect = 5e-06
Identities = 39/175 (22%), Positives = 73/175 (41%), Gaps = 6/175 (3%)
Frame = +1
Query: 64 ILLPFLLTCAIASAAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHL---RHA 228
+LLP LL A + +L + D LL Y + P D + +++ +
Sbjct: 12 LLLPTLLAQGEARRSRNTTRPALLRLSDYLLTNYTKGVRPVRDWRKPTTVSIDVIVYAIL 71
Query: 229 NIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAG 405
N+ E + + W D+ L WN ++ T L + ++ +W PD+++
Sbjct: 72 NVDEKNQVLTTYIWYRQYWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINELVDVGKS 131
Query: 406 DYALRARVSNNGSVSWIKRLDISTPISMQLDXWPNDMQTCTFGFGSXMHNIDXMD 570
+ + G V K L + T S+ + +P D+Q C+ F S +H I ++
Sbjct: 132 PNIPYVYIRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLHTIQDIN 186
>M59216-1|AAA35862.1| 474|Homo sapiens gamma-aminobutyric acid
receptor beta-1 subunit protein.
Length = 474
Score = 51.2 bits (117), Expect = 5e-06
Identities = 42/180 (23%), Positives = 76/180 (42%), Gaps = 9/180 (5%)
Frame = +1
Query: 61 IILLPFLLT--CAIASAAECENATSLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRH 225
++ P ++T C S E N + + +D LL YD PD + V + + +
Sbjct: 12 LLSFPVMITMVCCAHSTNEPSNMSYVKETVDRLLKGYDIRLRPDFGGPPVDVGMRIDVAS 71
Query: 226 AN-IRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTA 402
+ + E + Q +W DKRLS++ + +++LW PD LN +
Sbjct: 72 IDMVSEVNMDYTLTMYFQQSWKDKRLSYSGIPLNLTLDNRVADQLWVPDTYFLNDKKSFV 131
Query: 403 GDYALR---ARVSNNGSVSWIKRLDISTPISMQLDXWPNDMQTCTFGFGSXMHNIDXMDF 573
++ R+ +G+V + R+ + M L +P D Q CT S + D ++F
Sbjct: 132 HGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEF 191
>BC110597-1|AAI10598.1| 411|Homo sapiens ligand-gated ion channel,
zinc activated 1 protein.
Length = 411
Score = 50.8 bits (116), Expect = 6e-06
Identities = 27/101 (26%), Positives = 46/101 (45%)
Frame = +1
Query: 271 LQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVS 450
L+++W+D RL+WN + E LW P + +L A D + +ARV +G V
Sbjct: 86 LRLSWLDTRLAWNTSAHPRHAITLPWESLWTPRLTILEALWVDWRDQSPQARVDQDGHVK 145
Query: 451 WIKRLDISTPISMQLDXWPNDMQTCTFGFGSXMHNIDXMDF 573
L T + +L +P D C+ F + + ++F
Sbjct: 146 LNLALTTETNCNFELLHFPRDHSNCSLSFYALSNTAMELEF 186
>AF512521-1|AAO20969.1| 411|Homo sapiens ligand-gated ion channel
subunit protein.
Length = 411
Score = 50.8 bits (116), Expect = 6e-06
Identities = 27/101 (26%), Positives = 46/101 (45%)
Frame = +1
Query: 271 LQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVS 450
L+++W+D RL+WN + E LW P + +L A D + +ARV +G V
Sbjct: 86 LRLSWLDTRLAWNTSAHPRHAITLPWESLWTPRLTILEALWVDWRDQSPQARVDQDGHVK 145
Query: 451 WIKRLDISTPISMQLDXWPNDMQTCTFGFGSXMHNIDXMDF 573
L T + +L +P D C+ F + + ++F
Sbjct: 146 LNLALTTETNCNFELLHFPRDHSNCSLSFYALSNTAMELEF 186
>X14767-1|CAA32875.1| 474|Homo sapiens GABA-A receptor beta 1
subunit protein.
Length = 474
Score = 50.4 bits (115), Expect = 8e-06
Identities = 42/180 (23%), Positives = 75/180 (41%), Gaps = 9/180 (5%)
Frame = +1
Query: 61 IILLPFLLT--CAIASAAECENATSLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRH 225
++ P ++T C S E N + +D LL YD PD + V + + +
Sbjct: 12 LLSFPVMITMVCCAHSTNEPSNMPYVKETVDRLLKGYDIRLRPDFGGPPVDVGMRIDVAS 71
Query: 226 AN-IRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTA 402
+ + E + Q +W DKRLS++ + +++LW PD LN +
Sbjct: 72 IDMVSEVNMDYTLTMYFQQSWKDKRLSYSGIPLNLTLDNRVADQLWVPDTYFLNDKKSFV 131
Query: 403 GDYALR---ARVSNNGSVSWIKRLDISTPISMQLDXWPNDMQTCTFGFGSXMHNIDXMDF 573
++ R+ +G+V + R+ + M L +P D Q CT S + D ++F
Sbjct: 132 HGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEF 191
>D49394-1|BAA08387.1| 478|Homo sapiens serotonin 5-HT3 receptor
protein.
Length = 478
Score = 50.4 bits (115), Expect = 8e-06
Identities = 39/175 (22%), Positives = 73/175 (41%), Gaps = 6/175 (3%)
Frame = +1
Query: 64 ILLPFLLTCAIASAAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHL---RHA 228
+LLP LL A + +L + D LL Y + P D + +++ +
Sbjct: 12 LLLPTLLAQGEARRSRNTTRPALLRLSDYLLTNYRKGVRPVRDWRKPTTVSIDVIVYAIL 71
Query: 229 NIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAG 405
N+ E + + W D+ L WN ++ T L + ++ +W PD+++
Sbjct: 72 NVDEKNQVLTTYIWYRQYWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKS 131
Query: 406 DYALRARVSNNGSVSWIKRLDISTPISMQLDXWPNDMQTCTFGFGSXMHNIDXMD 570
+ + G V K L + T S+ + +P D+Q C+ F S +H I ++
Sbjct: 132 PNIPYVYIRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLHTIQDIN 186
>BT007204-1|AAP35868.1| 484|Homo sapiens 5-hydroxytryptamine
(serotonin) receptor 3A protein.
Length = 484
Score = 50.4 bits (115), Expect = 8e-06
Identities = 39/175 (22%), Positives = 73/175 (41%), Gaps = 6/175 (3%)
Frame = +1
Query: 64 ILLPFLLTCAIASAAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHL---RHA 228
+LLP LL A + +L + D LL Y + P D + +++ +
Sbjct: 18 LLLPTLLAQGEARRSRNTTRPALLRLSDYLLTNYRKGVRPVRDWRKPTTVSIDVIVYAIL 77
Query: 229 NIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAG 405
N+ E + + W D+ L WN ++ T L + ++ +W PD+++
Sbjct: 78 NVDEKNQVLTTYIWYRQYWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKS 137
Query: 406 DYALRARVSNNGSVSWIKRLDISTPISMQLDXWPNDMQTCTFGFGSXMHNIDXMD 570
+ + G V K L + T S+ + +P D+Q C+ F S +H I ++
Sbjct: 138 PNIPYVYIRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLHTIQDIN 192
>BC004453-1|AAH04453.2| 478|Homo sapiens 5-hydroxytryptamine
(serotonin) receptor 3A protein.
Length = 478
Score = 50.4 bits (115), Expect = 8e-06
Identities = 39/175 (22%), Positives = 73/175 (41%), Gaps = 6/175 (3%)
Frame = +1
Query: 64 ILLPFLLTCAIASAAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHL---RHA 228
+LLP LL A + +L + D LL Y + P D + +++ +
Sbjct: 12 LLLPTLLAQGEARRSRNTTRPALLRLSDYLLTNYRKGVRPVRDWRKPTTVSIDVIVYAIL 71
Query: 229 NIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAG 405
N+ E + + W D+ L WN ++ T L + ++ +W PD+++
Sbjct: 72 NVDEKNQVLTTYIWYRQYWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKS 131
Query: 406 DYALRARVSNNGSVSWIKRLDISTPISMQLDXWPNDMQTCTFGFGSXMHNIDXMD 570
+ + G V K L + T S+ + +P D+Q C+ F S +H I ++
Sbjct: 132 PNIPYVYIRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLHTIQDIN 186
>BC002354-1|AAH02354.1| 478|Homo sapiens 5-hydroxytryptamine
(serotonin) receptor 3A protein.
Length = 478
Score = 50.4 bits (115), Expect = 8e-06
Identities = 39/175 (22%), Positives = 73/175 (41%), Gaps = 6/175 (3%)
Frame = +1
Query: 64 ILLPFLLTCAIASAAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHL---RHA 228
+LLP LL A + +L + D LL Y + P D + +++ +
Sbjct: 12 LLLPTLLAQGEARRSRNTTRPALLRLSDYLLTNYRKGVRPVRDWRKPTTVSIDVIVYAIL 71
Query: 229 NIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAG 405
N+ E + + W D+ L WN ++ T L + ++ +W PD+++
Sbjct: 72 NVDEKNQVLTTYIWYRQYWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKS 131
Query: 406 DYALRARVSNNGSVSWIKRLDISTPISMQLDXWPNDMQTCTFGFGSXMHNIDXMD 570
+ + G V K L + T S+ + +P D+Q C+ F S +H I ++
Sbjct: 132 PNIPYVYIRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLHTIQDIN 186
>AJ005205-1|CAA06442.3| 478|Homo sapiens serotonin 3 receptor
protein.
Length = 478
Score = 50.4 bits (115), Expect = 8e-06
Identities = 39/175 (22%), Positives = 73/175 (41%), Gaps = 6/175 (3%)
Frame = +1
Query: 64 ILLPFLLTCAIASAAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHL---RHA 228
+LLP LL A + +L + D LL Y + P D + +++ +
Sbjct: 12 LLLPTLLAQGEARRSRNTTRPALLRLSDYLLTNYRKGVRPVRDWRKPTTVSIDVIVYAIL 71
Query: 229 NIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAG 405
N+ E + + W D+ L WN ++ T L + ++ +W PD+++
Sbjct: 72 NVDEKNQVLTTYIWYRQYWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKS 131
Query: 406 DYALRARVSNNGSVSWIKRLDISTPISMQLDXWPNDMQTCTFGFGSXMHNIDXMD 570
+ + G V K L + T S+ + +P D+Q C+ F S +H I ++
Sbjct: 132 PNIPYVYIRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLHTIQDIN 186
>AJ003079-1|CAA05852.1| 478|Homo sapiens 5-hydroxytryptamine3
receptor protein.
Length = 478
Score = 50.4 bits (115), Expect = 8e-06
Identities = 39/175 (22%), Positives = 73/175 (41%), Gaps = 6/175 (3%)
Frame = +1
Query: 64 ILLPFLLTCAIASAAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHL---RHA 228
+LLP LL A + +L + D LL Y + P D + +++ +
Sbjct: 12 LLLPTLLAQGEARRSRNTTRPALLRLSDYLLTNYRKGVRPVRDWRKPTTVSIDVIVYAIL 71
Query: 229 NIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAG 405
N+ E + + W D+ L WN ++ T L + ++ +W PD+++
Sbjct: 72 NVDEKNQVLTTYIWYRQYWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKS 131
Query: 406 DYALRARVSNNGSVSWIKRLDISTPISMQLDXWPNDMQTCTFGFGSXMHNIDXMD 570
+ + G V K L + T S+ + +P D+Q C+ F S +H I ++
Sbjct: 132 PNIPYVYIRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLHTIQDIN 186
>AJ003078-1|CAA05851.1| 510|Homo sapiens serotonin receptor
protein.
Length = 510
Score = 50.4 bits (115), Expect = 8e-06
Identities = 39/175 (22%), Positives = 73/175 (41%), Gaps = 6/175 (3%)
Frame = +1
Query: 64 ILLPFLLTCAIASAAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHL---RHA 228
+LLP LL A + +L + D LL Y + P D + +++ +
Sbjct: 12 LLLPTLLAQGEARRSRNTTRPALLRLSDYLLTNYRKGVRPVRDWRKPTTVSIDVIVYAIL 71
Query: 229 NIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAG 405
N+ E + + W D+ L WN ++ T L + ++ +W PD+++
Sbjct: 72 NVDEKNQVLTTYIWYRQYWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKS 131
Query: 406 DYALRARVSNNGSVSWIKRLDISTPISMQLDXWPNDMQTCTFGFGSXMHNIDXMD 570
+ + G V K L + T S+ + +P D+Q C+ F S +H I ++
Sbjct: 132 PNIPYVYIRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLHTIQDIN 186
>AF498984-1|AAM21131.1| 478|Homo sapiens 5-hydroxytryptamine
receptor 3A protein.
Length = 478
Score = 50.4 bits (115), Expect = 8e-06
Identities = 39/175 (22%), Positives = 73/175 (41%), Gaps = 6/175 (3%)
Frame = +1
Query: 64 ILLPFLLTCAIASAAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHL---RHA 228
+LLP LL A + +L + D LL Y + P D + +++ +
Sbjct: 12 LLLPTLLAQGEARRSRNTTRPALLRLSDYLLTNYRKGVRPVRDWRKPTTVSIDVIVYAIL 71
Query: 229 NIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAG 405
N+ E + + W D+ L WN ++ T L + ++ +W PD+++
Sbjct: 72 NVDEKNQVLTTYIWYRQYWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKS 131
Query: 406 DYALRARVSNNGSVSWIKRLDISTPISMQLDXWPNDMQTCTFGFGSXMHNIDXMD 570
+ + G V K L + T S+ + +P D+Q C+ F S +H I ++
Sbjct: 132 PNIPYVYIRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLHTIQDIN 186
>AB223030-1|BAE19924.1| 411|Homo sapiens ligand-gated ion-channel
receptor L2 protein.
Length = 411
Score = 50.4 bits (115), Expect = 8e-06
Identities = 27/101 (26%), Positives = 46/101 (45%)
Frame = +1
Query: 271 LQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVS 450
L+++W+D RL+WN + E LW P + +L A D + +ARV +G V
Sbjct: 86 LRLSWLDTRLAWNTSAHPRHAITLPWESLWTPRLTILEALWVDWRDQSPQARVDQDGHVK 145
Query: 451 WIKRLDISTPISMQLDXWPNDMQTCTFGFGSXMHNIDXMDF 573
L T + +L +P D C+ F + + ++F
Sbjct: 146 LNLALATETNCNFELLHFPRDHSNCSLSFYALSNTAMELEF 186
>AK122638-1|BAC85499.1| 266|Homo sapiens yte protein of 76kDa)
(LCP2). protein.
Length = 266
Score = 50.0 bits (114), Expect = 1e-05
Identities = 26/89 (29%), Positives = 41/89 (46%)
Frame = +1
Query: 271 LQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVS 450
L+++W+D RL+WN + E LW P + +L A D + +ARV +G V
Sbjct: 87 LRLSWLDTRLAWNTSAHPRHAITLPWESLWTPRLTILEALWVDWRDQSPQARVDQDGHVK 146
Query: 451 WIKRLDISTPISMQLDXWPNDMQTCTFGF 537
L T + +L +P D C+ F
Sbjct: 147 LNLALTTETNCNFELLHFPRDHSNCSLSF 175
>Z23141-1|CAA80672.1| 479|Homo sapiens cholinergic receptor,
nicotinic, alpha polypeptide 7 protein.
Length = 479
Score = 48.8 bits (111), Expect = 3e-05
Identities = 26/93 (27%), Positives = 45/93 (48%), Gaps = 2/93 (2%)
Frame = +1
Query: 271 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSNNGS 444
LQM+W D L WN E+ G T ++W+PD++L N+A + V+++G
Sbjct: 55 LQMSWTDHYLQWNVSEYPGVKTVRFPDGQIWKPDILLYNSADERFDATFHTNVLVNSSGH 114
Query: 445 VSWIKRLDISTPISMQLDXWPNDMQTCTFGFGS 543
++ + + + +P D+Q C FGS
Sbjct: 115 CQYLPPGIFKSSCYIDVRWFPFDVQHCKLKFGS 147
>Y08420-1|CAA69697.1| 502|Homo sapiens nicotinic acetylcholine
receptor alpha7 subunit precursor protein.
Length = 502
Score = 48.8 bits (111), Expect = 3e-05
Identities = 26/93 (27%), Positives = 45/93 (48%), Gaps = 2/93 (2%)
Frame = +1
Query: 271 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSNNGS 444
LQM+W D L WN E+ G T ++W+PD++L N+A + V+++G
Sbjct: 78 LQMSWTDHYLQWNVSEYPGVKTVRFPDGQIWKPDILLYNSADERFDATFHTNVLVNSSGH 137
Query: 445 VSWIKRLDISTPISMQLDXWPNDMQTCTFGFGS 543
++ + + + +P D+Q C FGS
Sbjct: 138 CQYLPPGIFKSSCYIDVRWFPFDVQHCKLKFGS 170
>X70297-1|CAA49778.1| 502|Homo sapiens neuronal nicotinic
acetylocholine receptor alpha-7 subunit protein.
Length = 502
Score = 48.8 bits (111), Expect = 3e-05
Identities = 26/93 (27%), Positives = 45/93 (48%), Gaps = 2/93 (2%)
Frame = +1
Query: 271 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSNNGS 444
LQM+W D L WN E+ G T ++W+PD++L N+A + V+++G
Sbjct: 78 LQMSWTDHYLQWNVSEYPGVKTVRFPDGQIWKPDILLYNSADERFDATFHTNVLVNSSGH 137
Query: 445 VSWIKRLDISTPISMQLDXWPNDMQTCTFGFGS 543
++ + + + +P D+Q C FGS
Sbjct: 138 CQYLPPGIFKSSCYIDVRWFPFDVQHCKLKFGS 170
>U62436-1|AAB40114.1| 502|Homo sapiens nicotinic acetylcholine
receptor alpha7 subunit precursor protein.
Length = 502
Score = 48.8 bits (111), Expect = 3e-05
Identities = 26/93 (27%), Positives = 45/93 (48%), Gaps = 2/93 (2%)
Frame = +1
Query: 271 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSNNGS 444
LQM+W D L WN E+ G T ++W+PD++L N+A + V+++G
Sbjct: 78 LQMSWTDHYLQWNVSEYPGVKTVRFPDGQIWKPDILLYNSADERFDATFHTNVLVNSSGH 137
Query: 445 VSWIKRLDISTPISMQLDXWPNDMQTCTFGFGS 543
++ + + + +P D+Q C FGS
Sbjct: 138 CQYLPPGIFKSSCYIDVRWFPFDVQHCKLKFGS 170
>AJ586911-1|CAE52911.1| 502|Homo sapiens nicotinic acetylcholine
alpha-7 subunit protein.
Length = 502
Score = 48.8 bits (111), Expect = 3e-05
Identities = 26/93 (27%), Positives = 45/93 (48%), Gaps = 2/93 (2%)
Frame = +1
Query: 271 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSNNGS 444
LQM+W D L WN E+ G T ++W+PD++L N+A + V+++G
Sbjct: 78 LQMSWTDHYLQWNVSEYPGVKTVRFPDGQIWKPDILLYNSADERFDATFHTNVLVNSSGH 137
Query: 445 VSWIKRLDISTPISMQLDXWPNDMQTCTFGFGS 543
++ + + + +P D+Q C FGS
Sbjct: 138 CQYLPPGIFKSSCYIDVRWFPFDVQHCKLKFGS 170
>U40583-1|AAA83561.1| 502|Homo sapiens alpha 7 neuronal nicotinic
acetylcholine receptor protein.
Length = 502
Score = 47.6 bits (108), Expect = 6e-05
Identities = 26/93 (27%), Positives = 44/93 (47%), Gaps = 2/93 (2%)
Frame = +1
Query: 271 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSNNGS 444
LQM+W D L WN E+ G T ++W+PD++L N+A + V+ +G
Sbjct: 78 LQMSWTDHYLQWNVSEYPGVKTVRFPDGQIWKPDILLYNSADERFDATFHTNVLVNPSGH 137
Query: 445 VSWIKRLDISTPISMQLDXWPNDMQTCTFGFGS 543
++ + + + +P D+Q C FGS
Sbjct: 138 CQYLPPGIFKSSCYIDVRWFPFDVQHCKLKFGS 170
>AF385585-1|AAK68111.1| 502|Homo sapiens nicotinic cholinergic
receptor alpha 7 protein.
Length = 502
Score = 47.6 bits (108), Expect = 6e-05
Identities = 26/93 (27%), Positives = 44/93 (47%), Gaps = 2/93 (2%)
Frame = +1
Query: 271 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSNNGS 444
LQM+W D L WN E+ G T ++W+PD++L N+A + V+ +G
Sbjct: 78 LQMSWTDHYLQWNVSEYPGVKTVRFPDGQIWKPDILLYNSADERFDATFHTNVLVNPSGH 137
Query: 445 VSWIKRLDISTPISMQLDXWPNDMQTCTFGFGS 543
++ + + + +P D+Q C FGS
Sbjct: 138 CQYLPPGIFKSSCYIDVRWFPFDVQHCKLKFGS 170
>L08485-1|AAA58490.1| 462|Homo sapiens GABA-benzodiazepine receptor
alpha-5-subunit protein.
Length = 462
Score = 47.2 bits (107), Expect = 8e-05
Identities = 36/150 (24%), Positives = 65/150 (43%), Gaps = 7/150 (4%)
Frame = +1
Query: 115 ENATSLSLMIDSLLATYDRESPPD--SKIV-VNLTLHLRHAN-IRESESTVRILADLQMN 282
+N T + ++D LL YD P +I V +++ + ++E I + +
Sbjct: 44 DNITIFTRILDGLLDGYDNRLRPGLGERITQVRTDIYVTSFGPVSDTEMEYTIDVFFRQS 103
Query: 283 WIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSW 453
W D+RL + + + ++W PD N + A + R+ ++G++ +
Sbjct: 104 WKDERLRFKGPMQRLPLNNLLASKIWTPDTFFHNGKKSIAHNMTTPNKLLRLEDDGTLLY 163
Query: 454 IKRLDISTPISMQLDXWPNDMQTCTFGFGS 543
RL IS MQL+ +P D C FGS
Sbjct: 164 TMRLTISAECPMQLEDFPMDAHACPLKFGS 193
>BT009830-1|AAP88832.1| 462|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 5 protein.
Length = 462
Score = 47.2 bits (107), Expect = 8e-05
Identities = 36/150 (24%), Positives = 65/150 (43%), Gaps = 7/150 (4%)
Frame = +1
Query: 115 ENATSLSLMIDSLLATYDRESPPD--SKIV-VNLTLHLRHAN-IRESESTVRILADLQMN 282
+N T + ++D LL YD P +I V +++ + ++E I + +
Sbjct: 44 DNITIFTRILDGLLDGYDNRLRPGLGERITQVRTDIYVTSFGPVSDTEMEYTIDVFFRQS 103
Query: 283 WIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSW 453
W D+RL + + + ++W PD N + A + R+ ++G++ +
Sbjct: 104 WKDERLRFKGPMQRLPLNNLLASKIWTPDTFFHNGKKSIAHNMTTPNKLLRLEDDGTLLY 163
Query: 454 IKRLDISTPISMQLDXWPNDMQTCTFGFGS 543
RL IS MQL+ +P D C FGS
Sbjct: 164 TMRLTISAECPMQLEDFPMDAHACPLKFGS 193
>BC113422-1|AAI13423.1| 462|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 5 protein.
Length = 462
Score = 47.2 bits (107), Expect = 8e-05
Identities = 36/150 (24%), Positives = 65/150 (43%), Gaps = 7/150 (4%)
Frame = +1
Query: 115 ENATSLSLMIDSLLATYDRESPPD--SKIV-VNLTLHLRHAN-IRESESTVRILADLQMN 282
+N T + ++D LL YD P +I V +++ + ++E I + +
Sbjct: 44 DNITIFTRILDGLLDGYDNRLRPGLGERITQVRTDIYVTSFGPVSDTEMEYTIDVFFRQS 103
Query: 283 WIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSW 453
W D+RL + + + ++W PD N + A + R+ ++G++ +
Sbjct: 104 WKDERLRFKGPMQRLPLNNLLASKIWTPDTFFHNGKKSIAHNMTTPNKLLRLEDDGTLLY 163
Query: 454 IKRLDISTPISMQLDXWPNDMQTCTFGFGS 543
RL IS MQL+ +P D C FGS
Sbjct: 164 TMRLTISAECPMQLEDFPMDAHACPLKFGS 193
>BC111979-1|AAI11980.1| 462|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 5, precursor protein.
Length = 462
Score = 47.2 bits (107), Expect = 8e-05
Identities = 36/150 (24%), Positives = 65/150 (43%), Gaps = 7/150 (4%)
Frame = +1
Query: 115 ENATSLSLMIDSLLATYDRESPPD--SKIV-VNLTLHLRHAN-IRESESTVRILADLQMN 282
+N T + ++D LL YD P +I V +++ + ++E I + +
Sbjct: 44 DNITIFTRILDGLLDGYDNRLRPGLGERITQVRTDIYVTSFGPVSDTEMEYTIDVFFRQS 103
Query: 283 WIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSW 453
W D+RL + + + ++W PD N + A + R+ ++G++ +
Sbjct: 104 WKDERLRFKGPMQRLPLNNLLASKIWTPDTFFHNGKKSIAHNMTTPNKLLRLEDDGTLLY 163
Query: 454 IKRLDISTPISMQLDXWPNDMQTCTFGFGS 543
RL IS MQL+ +P D C FGS
Sbjct: 164 TMRLTISAECPMQLEDFPMDAHACPLKFGS 193
>BC109211-1|AAI09212.1| 632|Homo sapiens gamma-aminobutyric acid
(GABA) receptor, theta protein.
Length = 632
Score = 46.8 bits (106), Expect = 1e-04
Identities = 36/157 (22%), Positives = 64/157 (40%), Gaps = 7/157 (4%)
Frame = +1
Query: 112 CENATSLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESESTVRILADLQM 279
C N + ++D +L+ YD P+ + + V +++++ I E I
Sbjct: 53 CANEAVVQKILDRVLSRYDVRLRPNFGGAPVPVRISIYVTSIEQISEMNMDYTITMFFHQ 112
Query: 280 NWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSN---NGSVS 450
W D RL++ + E+LW PD LN+ D + RV +G+V
Sbjct: 113 TWKDSRLAYYETTLNLTLDYRMHEKLWVPDCYFLNSKDAFVHDVTVENRVFQLHPDGTVR 172
Query: 451 WIKRLDISTPISMQLDXWPNDMQTCTFGFGSXMHNID 561
+ RL + S+ L +P D Q C S + ++
Sbjct: 173 YGIRLTTTAACSLDLHKFPMDKQACNLVVESYGYTVE 209
>BC109210-1|AAI09211.1| 632|Homo sapiens gamma-aminobutyric acid
(GABA) receptor, theta protein.
Length = 632
Score = 46.8 bits (106), Expect = 1e-04
Identities = 36/157 (22%), Positives = 64/157 (40%), Gaps = 7/157 (4%)
Frame = +1
Query: 112 CENATSLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESESTVRILADLQM 279
C N + ++D +L+ YD P+ + + V +++++ I E I
Sbjct: 53 CANEAVVQKILDRVLSRYDVRLRPNFGGAPVPVRISIYVTSIEQISEMNMDYTITMFFHQ 112
Query: 280 NWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSN---NGSVS 450
W D RL++ + E+LW PD LN+ D + RV +G+V
Sbjct: 113 TWKDSRLAYYETTLNLTLDYRMHEKLWVPDCYFLNSKDAFVHDVTVENRVFQLHPDGTVR 172
Query: 451 WIKRLDISTPISMQLDXWPNDMQTCTFGFGSXMHNID 561
+ RL + S+ L +P D Q C S + ++
Sbjct: 173 YGIRLTTTAACSLDLHKFPMDKQACNLVVESYGYTVE 209
>BC096083-1|AAH96083.1| 198|Homo sapiens CHRNB4 protein protein.
Length = 198
Score = 46.8 bits (106), Expect = 1e-04
Identities = 33/123 (26%), Positives = 58/123 (47%), Gaps = 8/123 (6%)
Frame = +1
Query: 67 LLPFLLTCAIASAAECENATSLSLMIDSLL--ATYDRESPP--DSKIVVNLTLHLRHA-- 228
L+ F L A+ C A + ++D LL Y+ P S ++++ L L A
Sbjct: 7 LVLFFLV-ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQL 65
Query: 229 -NIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTA 402
++ E E + L+ W D RL+WN+ + G + + ++R+W PD+VL N + T
Sbjct: 66 ISVNEREQIMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNKSLRTG 125
Query: 403 GDY 411
+
Sbjct: 126 STW 128
>BC096081-1|AAH96081.1| 198|Homo sapiens CHRNB4 protein protein.
Length = 198
Score = 46.8 bits (106), Expect = 1e-04
Identities = 33/123 (26%), Positives = 58/123 (47%), Gaps = 8/123 (6%)
Frame = +1
Query: 67 LLPFLLTCAIASAAECENATSLSLMIDSLL--ATYDRESPP--DSKIVVNLTLHLRHA-- 228
L+ F L A+ C A + ++D LL Y+ P S ++++ L L A
Sbjct: 7 LVLFFLV-ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQL 65
Query: 229 -NIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTA 402
++ E E + L+ W D RL+WN+ + G + + ++R+W PD+VL N + T
Sbjct: 66 ISVNEREQIMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNKSLRTG 125
Query: 403 GDY 411
+
Sbjct: 126 STW 128
>AF189259-1|AAF70380.1| 632|Homo sapiens GABA-A receptor theta
subunit protein.
Length = 632
Score = 46.8 bits (106), Expect = 1e-04
Identities = 36/157 (22%), Positives = 64/157 (40%), Gaps = 7/157 (4%)
Frame = +1
Query: 112 CENATSLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESESTVRILADLQM 279
C N + ++D +L+ YD P+ + + V +++++ I E I
Sbjct: 53 CANEAVVQKILDRVLSRYDVRLRPNFGGAPVPVRISIYVTSIEQISEMNMDYTITMFFHQ 112
Query: 280 NWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSN---NGSVS 450
W D RL++ + E+LW PD LN+ D + RV +G+V
Sbjct: 113 TWKDSRLAYYETTLNLTLDYRMHEKLWVPDCYFLNSKDAFVHDVTVENRVFQLHPDGTVR 172
Query: 451 WIKRLDISTPISMQLDXWPNDMQTCTFGFGSXMHNID 561
+ RL + S+ L +P D Q C S + ++
Sbjct: 173 YGIRLTTTAACSLDLHKFPMDKQACNLVVESYGYTVE 209
>AF144648-1|AAD51172.1| 627|Homo sapiens GABA-A receptor theta
protein.
Length = 627
Score = 46.8 bits (106), Expect = 1e-04
Identities = 36/157 (22%), Positives = 64/157 (40%), Gaps = 7/157 (4%)
Frame = +1
Query: 112 CENATSLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESESTVRILADLQM 279
C N + ++D +L+ YD P+ + + V +++++ I E I
Sbjct: 48 CANEAVVQKILDRVLSRYDVRLRPNFGGAPVPVRISIYVTSIEQISEMNMDYTITMFFHQ 107
Query: 280 NWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSN---NGSVS 450
W D RL++ + E+LW PD LN+ D + RV +G+V
Sbjct: 108 TWKDSRLAYYETTLNLTLDYRMHEKLWVPDCYFLNSKDAFVHDVTVENRVFQLHPDGTVR 167
Query: 451 WIKRLDISTPISMQLDXWPNDMQTCTFGFGSXMHNID 561
+ RL + S+ L +P D Q C S + ++
Sbjct: 168 YGIRLTTTAACSLDLHKFPMDKQACNLVVESYGYTVE 204
>U77731-2|AAB38273.1| 360|Homo sapiens glycine receptor alpha 2B
subunit protein.
Length = 360
Score = 46.4 bits (105), Expect = 1e-04
Identities = 38/145 (26%), Positives = 63/145 (43%), Gaps = 8/145 (5%)
Frame = +1
Query: 163 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 330
YD P+ K VN+T ++ +I E+ R+ L+ W D RL+++
Sbjct: 58 YDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDSRLAYSEYPDDSL 117
Query: 331 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLD 498
S + +W+PD+ N D R+S NG V + RL ++ M L
Sbjct: 118 DLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLK 177
Query: 499 XWPNDMQTCTFGFGSXMHNIDXMDF 573
+P D+QTCT S + ++ + F
Sbjct: 178 NFPMDVQTCTMQLESFGYTMNDLIF 202
>CR450343-1|CAG29339.1| 452|Homo sapiens GLRA2 protein.
Length = 452
Score = 46.4 bits (105), Expect = 1e-04
Identities = 38/145 (26%), Positives = 63/145 (43%), Gaps = 8/145 (5%)
Frame = +1
Query: 163 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 330
YD P+ K VN+T ++ +I E+ R+ L+ W D RL+++
Sbjct: 58 YDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDSRLAYSEYPDDSL 117
Query: 331 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLD 498
S + +W+PD+ N D R+S NG V + RL ++ M L
Sbjct: 118 DLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLK 177
Query: 499 XWPNDMQTCTFGFGSXMHNIDXMDF 573
+P D+QTCT S + ++ + F
Sbjct: 178 NFPMDVQTCTMQLESFGYTMNDLIF 202
>AY437084-1|AAR87843.1| 452|Homo sapiens glycine receptor alpha2
subunit B protein.
Length = 452
Score = 46.4 bits (105), Expect = 1e-04
Identities = 38/145 (26%), Positives = 63/145 (43%), Gaps = 8/145 (5%)
Frame = +1
Query: 163 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 330
YD P+ K VN+T ++ +I E+ R+ L+ W D RL+++
Sbjct: 58 YDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDSRLAYSEYPDDSL 117
Query: 331 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLD 498
S + +W+PD+ N D R+S NG V + RL ++ M L
Sbjct: 118 DLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLK 177
Query: 499 XWPNDMQTCTFGFGSXMHNIDXMDF 573
+P D+QTCT S + ++ + F
Sbjct: 178 NFPMDVQTCTMQLESFGYTMNDLIF 202
>X52008-1|CAA36257.1| 452|Homo sapiens inhibitory glycine receptor
protein.
Length = 452
Score = 46.0 bits (104), Expect = 2e-04
Identities = 37/145 (25%), Positives = 63/145 (43%), Gaps = 8/145 (5%)
Frame = +1
Query: 163 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 330
YD P+ K VN+T ++ ++ E+ R+ L+ W D RL+++
Sbjct: 58 YDARIRPNFKGPPVNVTCNIFINSFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPDDSL 117
Query: 331 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLD 498
S + +W+PD+ N D R+S NG V + RL ++ M L
Sbjct: 118 DLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLK 177
Query: 499 XWPNDMQTCTFGFGSXMHNIDXMDF 573
+P D+QTCT S + ++ + F
Sbjct: 178 NFPMDVQTCTMQLESFGYTMNDLIF 202
>U77731-1|AAB38272.1| 360|Homo sapiens glycine receptor alpha 2
subunit protein.
Length = 360
Score = 46.0 bits (104), Expect = 2e-04
Identities = 37/145 (25%), Positives = 63/145 (43%), Gaps = 8/145 (5%)
Frame = +1
Query: 163 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 330
YD P+ K VN+T ++ ++ E+ R+ L+ W D RL+++
Sbjct: 58 YDARIRPNFKGPPVNVTCNIFINSFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPDDSL 117
Query: 331 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLD 498
S + +W+PD+ N D R+S NG V + RL ++ M L
Sbjct: 118 DLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLK 177
Query: 499 XWPNDMQTCTFGFGSXMHNIDXMDF 573
+P D+QTCT S + ++ + F
Sbjct: 178 NFPMDVQTCTMQLESFGYTMNDLIF 202
>BC032864-1|AAH32864.1| 452|Homo sapiens glycine receptor, alpha 2
protein.
Length = 452
Score = 46.0 bits (104), Expect = 2e-04
Identities = 37/145 (25%), Positives = 63/145 (43%), Gaps = 8/145 (5%)
Frame = +1
Query: 163 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 330
YD P+ K VN+T ++ ++ E+ R+ L+ W D RL+++
Sbjct: 58 YDARIRPNFKGPPVNVTCNIFINSFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPDDSL 117
Query: 331 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLD 498
S + +W+PD+ N D R+S NG V + RL ++ M L
Sbjct: 118 DLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLK 177
Query: 499 XWPNDMQTCTFGFGSXMHNIDXMDF 573
+P D+QTCT S + ++ + F
Sbjct: 178 NFPMDVQTCTMQLESFGYTMNDLIF 202
>BC028629-1|AAH28629.1| 492|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 3 protein.
Length = 492
Score = 46.0 bits (104), Expect = 2e-04
Identities = 34/150 (22%), Positives = 64/150 (42%), Gaps = 7/150 (4%)
Frame = +1
Query: 115 ENATSLSLMIDSLLATYDRESPP---DSKIVVNLTLHLRHAN-IRESESTVRILADLQMN 282
+N T + ++D LL YD P D+ V +++ + +++ I +
Sbjct: 62 DNITIFTRILDRLLDGYDNRLRPGLGDAVTEVKTDIYVTSFGPVSDTDMEYTIDVFFRQT 121
Query: 283 WIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSW 453
W D+RL ++ + + ++W PD N + A + R+ +NG++ +
Sbjct: 122 WHDERLKFDGPMKILPLNNLLASKIWTPDTFFHNGKKSVAHNMTTPNKLLRLVDNGTLPY 181
Query: 454 IKRLDISTPISMQLDXWPNDMQTCTFGFGS 543
RL I M L+ +P D+ C FGS
Sbjct: 182 TMRLTIHAECPMHLEDFPMDVHACPLKFGS 211
>BC022449-1|AAH22449.1| 474|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, beta 1 protein.
Length = 474
Score = 46.0 bits (104), Expect = 2e-04
Identities = 41/180 (22%), Positives = 75/180 (41%), Gaps = 9/180 (5%)
Frame = +1
Query: 61 IILLPFLLT--CAIASAAECENATSLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRH 225
++ P ++T C S E N + + +D LL YD PD + V + + +
Sbjct: 12 LLSFPVMITMVCCAHSTNEPSNMSYVKETVDRLLKGYDIRLRPDFGGPPVDVGMRIDVAS 71
Query: 226 AN-IRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTA 402
+ + E + Q +W DKRLS++ + +++L PD LN +
Sbjct: 72 IDMVSEVNMDYTLTMYFQQSWKDKRLSYSGIPLNLTLDNRVADQLCVPDTYFLNDKKSFV 131
Query: 403 GDYALR---ARVSNNGSVSWIKRLDISTPISMQLDXWPNDMQTCTFGFGSXMHNIDXMDF 573
++ R+ +G+V + R+ + M L +P D Q CT S + D ++F
Sbjct: 132 HGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEF 191
>AY437083-1|AAR87842.1| 452|Homo sapiens glycine receptor alpha2
subunit A protein.
Length = 452
Score = 46.0 bits (104), Expect = 2e-04
Identities = 37/145 (25%), Positives = 63/145 (43%), Gaps = 8/145 (5%)
Frame = +1
Query: 163 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 330
YD P+ K VN+T ++ ++ E+ R+ L+ W D RL+++
Sbjct: 58 YDARIRPNFKGPPVNVTCNIFINSFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPDDSL 117
Query: 331 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLD 498
S + +W+PD+ N D R+S NG V + RL ++ M L
Sbjct: 118 DLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLK 177
Query: 499 XWPNDMQTCTFGFGSXMHNIDXMDF 573
+P D+QTCT S + ++ + F
Sbjct: 178 NFPMDVQTCTMQLESFGYTMNDLIF 202
>AF053495-1|AAC35290.1| 452|Homo sapiens glycine receptor alpha 2
subunit protein.
Length = 452
Score = 46.0 bits (104), Expect = 2e-04
Identities = 37/145 (25%), Positives = 63/145 (43%), Gaps = 8/145 (5%)
Frame = +1
Query: 163 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 330
YD P+ K VN+T ++ ++ E+ R+ L+ W D RL+++
Sbjct: 58 YDARIRPNFKGPPVNVTCNIFINSFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPDDSL 117
Query: 331 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLD 498
S + +W+PD+ N D R+S NG V + RL ++ M L
Sbjct: 118 DLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLK 177
Query: 499 XWPNDMQTCTFGFGSXMHNIDXMDF 573
+P D+QTCT S + ++ + F
Sbjct: 178 NFPMDVQTCTMQLESFGYTMNDLIF 202
>S62908-1|AAB27279.1| 492|Homo sapiens gamma-aminobutyric acidA
receptor alpha 3 subunit protein.
Length = 492
Score = 45.6 bits (103), Expect = 2e-04
Identities = 34/150 (22%), Positives = 64/150 (42%), Gaps = 7/150 (4%)
Frame = +1
Query: 115 ENATSLSLMIDSLLATYDRESPP---DSKIVVNLTLHLRHAN-IRESESTVRILADLQMN 282
+N T + ++D LL YD P D+ V +++ + +++ I +
Sbjct: 62 DNITIFTRILDRLLDGYDNRLRPGLGDAVTEVKTDIYVTSFGPVSDTDMEYTIDVFFRQT 121
Query: 283 WIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSW 453
W D+RL ++ + + ++W PD N + A + R+ +NG++ +
Sbjct: 122 WHDERLKFDGPMKILPLNNLLASKIWTPDTFFHNGKKSVAHNMTTPNKLLRLVDNGTLLY 181
Query: 454 IKRLDISTPISMQLDXWPNDMQTCTFGFGS 543
RL I M L+ +P D+ C FGS
Sbjct: 182 TMRLTIHAECPMHLEDFPMDVHACPLKFGS 211
>AF166361-1|AAG12455.1| 492|Homo sapiens GABA receptor subunit
alpha 3 protein.
Length = 492
Score = 45.6 bits (103), Expect = 2e-04
Identities = 34/150 (22%), Positives = 64/150 (42%), Gaps = 7/150 (4%)
Frame = +1
Query: 115 ENATSLSLMIDSLLATYDRESPP---DSKIVVNLTLHLRHAN-IRESESTVRILADLQMN 282
+N T + ++D LL YD P D+ V +++ + +++ I +
Sbjct: 62 DNITIFTRILDRLLDGYDNRLRPGLGDAVTEVKTDIYVTSFGPVSDTDMEYTIDVFFRQT 121
Query: 283 WIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSW 453
W D+RL ++ + + ++W PD N + A + R+ +NG++ +
Sbjct: 122 WHDERLKFDGPMKILPLNNLLASKIWTPDTFFHNGKKSVAHNMTTPNKLLRLVDNGTLLY 181
Query: 454 IKRLDISTPISMQLDXWPNDMQTCTFGFGS 543
RL I M L+ +P D+ C FGS
Sbjct: 182 TMRLTIHAECPMHLEDFPMDVHACPLKFGS 211
>BC033801-1|AAH33801.1| 452|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, delta protein.
Length = 452
Score = 43.6 bits (98), Expect = 0.001
Identities = 36/135 (26%), Positives = 57/135 (42%), Gaps = 7/135 (5%)
Frame = +1
Query: 142 IDSLLATYDRESPPD-SKIVVNLTLHLRHANI---RESESTVRILADLQMNWIDKRLSWN 309
+D L+A Y R P VN+ L L A+I E+ + L +W D RLS+N
Sbjct: 44 LDGLIAGYARNFRPGIGGPPVNVALALEVASIDHISEANMEYTMTVFLHQSWRDSRLSYN 103
Query: 310 AGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTP 480
++LW PD ++NA + D + R+ +G + + R+ +
Sbjct: 104 HTNETLGLDSRFVDKLWLPDTFIVNAKSAWFHDVTVENKLIRLQPDGVILYSIRITSTVA 163
Query: 481 ISMQLDXWPNDMQTC 525
M L +P D Q C
Sbjct: 164 CDMDLAKYPMDEQEC 178
>AL391845-4|CAI15436.1| 452|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, delta protein.
Length = 452
Score = 43.6 bits (98), Expect = 0.001
Identities = 36/135 (26%), Positives = 57/135 (42%), Gaps = 7/135 (5%)
Frame = +1
Query: 142 IDSLLATYDRESPPD-SKIVVNLTLHLRHANI---RESESTVRILADLQMNWIDKRLSWN 309
+D L+A Y R P VN+ L L A+I E+ + L +W D RLS+N
Sbjct: 44 LDGLIAGYARNFRPGIGGPPVNVALALEVASIDHISEANMEYTMTVFLHQSWRDSRLSYN 103
Query: 310 AGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTP 480
++LW PD ++NA + D + R+ +G + + R+ +
Sbjct: 104 HTNETLGLDSRFVDKLWLPDTFIVNAKSAWFHDVTVENKLIRLQPDGVILYSIRITSTVA 163
Query: 481 ISMQLDXWPNDMQTC 525
M L +P D Q C
Sbjct: 164 CDMDLAKYPMDEQEC 178
>AF016917-1|AAB70007.1| 452|Homo sapiens GABA-A receptor delta
subunit protein.
Length = 452
Score = 43.6 bits (98), Expect = 0.001
Identities = 36/135 (26%), Positives = 57/135 (42%), Gaps = 7/135 (5%)
Frame = +1
Query: 142 IDSLLATYDRESPPD-SKIVVNLTLHLRHANI---RESESTVRILADLQMNWIDKRLSWN 309
+D L+A Y R P VN+ L L A+I E+ + L +W D RLS+N
Sbjct: 44 LDGLIAGYARNFRPGIGGPPVNVALALEVASIDHISEANMEYTMTVFLHQSWRDSRLSYN 103
Query: 310 AGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTP 480
++LW PD ++NA + D + R+ +G + + R+ +
Sbjct: 104 HTNETLGLDSRFVDKLWLPDTFIVNAKSAWFHDVTVENKLIRLQPDGVILYSIRITSTVA 163
Query: 481 ISMQLDXWPNDMQTC 525
M L +P D Q C
Sbjct: 164 CDMDLAKYPMDEQEC 178
>U95367-1|AAC51357.1| 440|Homo sapiens GABA-A receptor pi subunit
protein.
Length = 440
Score = 43.2 bits (97), Expect = 0.001
Identities = 40/164 (24%), Positives = 76/164 (46%), Gaps = 9/164 (5%)
Frame = +1
Query: 109 ECENATSLSLM-IDSLLATYDRESPPD---SKIVVNLTLHLRH-ANIRESESTVRILADL 273
E + LSL ++L A Y++ P+ + + LTL + ++I ES L
Sbjct: 29 EVGRSDKLSLPGFENLTAGYNKFLRPNFGGEPVQIALTLDIASISSISESNMDYTATIYL 88
Query: 274 QMNWIDKRLSWNAGE-WGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNG 441
+ W+D+RL + + + LV E LW PD ++ + + + + R+ +NG
Sbjct: 89 RQRWMDQRLVFEGNKSFTLDARLV--EFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNG 146
Query: 442 SVSWIKRLDISTPISMQLDXWPNDMQTCTFGFGSXMHNIDXMDF 573
+V + R+ + +M L +P D QTC S ++ + ++F
Sbjct: 147 TVLYALRITTTVACNMDLSKYPMDTQTCKLQLESWGYDGNDVEF 190
>BC109106-1|AAI09107.1| 440|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, pi protein.
Length = 440
Score = 43.2 bits (97), Expect = 0.001
Identities = 40/164 (24%), Positives = 76/164 (46%), Gaps = 9/164 (5%)
Frame = +1
Query: 109 ECENATSLSLM-IDSLLATYDRESPPD---SKIVVNLTLHLRH-ANIRESESTVRILADL 273
E + LSL ++L A Y++ P+ + + LTL + ++I ES L
Sbjct: 29 EVGRSDKLSLPGFENLTAGYNKFLRPNFGGEPVQIALTLDIASISSISESNMDYTATIYL 88
Query: 274 QMNWIDKRLSWNAGE-WGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNG 441
+ W+D+RL + + + LV E LW PD ++ + + + + R+ +NG
Sbjct: 89 RQRWMDQRLVFEGNKSFTLDARLV--EFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNG 146
Query: 442 SVSWIKRLDISTPISMQLDXWPNDMQTCTFGFGSXMHNIDXMDF 573
+V + R+ + +M L +P D QTC S ++ + ++F
Sbjct: 147 TVLYALRITTTVACNMDLSKYPMDTQTCKLQLESWGYDGNDVEF 190
>BC109105-1|AAI09106.1| 440|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, pi protein.
Length = 440
Score = 43.2 bits (97), Expect = 0.001
Identities = 40/164 (24%), Positives = 76/164 (46%), Gaps = 9/164 (5%)
Frame = +1
Query: 109 ECENATSLSLM-IDSLLATYDRESPPD---SKIVVNLTLHLRH-ANIRESESTVRILADL 273
E + LSL ++L A Y++ P+ + + LTL + ++I ES L
Sbjct: 29 EVGRSDKLSLPGFENLTAGYNKFLRPNFGGEPVQIALTLDIASISSISESNMDYTATIYL 88
Query: 274 QMNWIDKRLSWNAGE-WGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNG 441
+ W+D+RL + + + LV E LW PD ++ + + + + R+ +NG
Sbjct: 89 RQRWMDQRLVFEGNKSFTLDARLV--EFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNG 146
Query: 442 SVSWIKRLDISTPISMQLDXWPNDMQTCTFGFGSXMHNIDXMDF 573
+V + R+ + +M L +P D QTC S ++ + ++F
Sbjct: 147 TVLYALRITTTVACNMDLSKYPMDTQTCKLQLESWGYDGNDVEF 190
>BC074865-1|AAH74865.1| 440|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, pi protein.
Length = 440
Score = 43.2 bits (97), Expect = 0.001
Identities = 40/164 (24%), Positives = 76/164 (46%), Gaps = 9/164 (5%)
Frame = +1
Query: 109 ECENATSLSLM-IDSLLATYDRESPPD---SKIVVNLTLHLRH-ANIRESESTVRILADL 273
E + LSL ++L A Y++ P+ + + LTL + ++I ES L
Sbjct: 29 EVGRSDKLSLPGFENLTAGYNKFLRPNFGGEPVQIALTLDIASISSISESNMDYTATIYL 88
Query: 274 QMNWIDKRLSWNAGE-WGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNG 441
+ W+D+RL + + + LV E LW PD ++ + + + + R+ +NG
Sbjct: 89 RQRWMDQRLVFEGNKSFTLDARLV--EFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNG 146
Query: 442 SVSWIKRLDISTPISMQLDXWPNDMQTCTFGFGSXMHNIDXMDF 573
+V + R+ + +M L +P D QTC S ++ + ++F
Sbjct: 147 TVLYALRITTTVACNMDLSKYPMDTQTCKLQLESWGYDGNDVEF 190
>BC074810-1|AAH74810.1| 440|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, pi protein.
Length = 440
Score = 43.2 bits (97), Expect = 0.001
Identities = 40/164 (24%), Positives = 76/164 (46%), Gaps = 9/164 (5%)
Frame = +1
Query: 109 ECENATSLSLM-IDSLLATYDRESPPD---SKIVVNLTLHLRH-ANIRESESTVRILADL 273
E + LSL ++L A Y++ P+ + + LTL + ++I ES L
Sbjct: 29 EVGRSDKLSLPGFENLTAGYNKFLRPNFGGEPVQIALTLDIASISSISESNMDYTATIYL 88
Query: 274 QMNWIDKRLSWNAGE-WGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNG 441
+ W+D+RL + + + LV E LW PD ++ + + + + R+ +NG
Sbjct: 89 RQRWMDQRLVFEGNKSFTLDARLV--EFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNG 146
Query: 442 SVSWIKRLDISTPISMQLDXWPNDMQTCTFGFGSXMHNIDXMDF 573
+V + R+ + +M L +P D QTC S ++ + ++F
Sbjct: 147 TVLYALRITTTVACNMDLSKYPMDTQTCKLQLESWGYDGNDVEF 190
>AF009702-1|AAC24194.1| 440|Homo sapiens GABA-A receptor pi subunit
protein.
Length = 440
Score = 43.2 bits (97), Expect = 0.001
Identities = 40/164 (24%), Positives = 76/164 (46%), Gaps = 9/164 (5%)
Frame = +1
Query: 109 ECENATSLSLM-IDSLLATYDRESPPD---SKIVVNLTLHLRH-ANIRESESTVRILADL 273
E + LSL ++L A Y++ P+ + + LTL + ++I ES L
Sbjct: 29 EVGRSDKLSLPGFENLTAGYNKFLRPNFGGEPVQIALTLDIASISSISESNMDYTATIYL 88
Query: 274 QMNWIDKRLSWNAGE-WGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNG 441
+ W+D+RL + + + LV E LW PD ++ + + + + R+ +NG
Sbjct: 89 RQRWMDQRLVFEGNKSFTLDARLV--EFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNG 146
Query: 442 SVSWIKRLDISTPISMQLDXWPNDMQTCTFGFGSXMHNIDXMDF 573
+V + R+ + +M L +P D QTC S ++ + ++F
Sbjct: 147 TVLYALRITTTVACNMDLSKYPMDTQTCKLQLESWGYDGNDVEF 190
>U93917-1|AAC39917.1| 449|Homo sapiens glycine receptor alpha 3
subunit protein.
Length = 449
Score = 42.3 bits (95), Expect = 0.002
Identities = 44/181 (24%), Positives = 75/181 (41%), Gaps = 11/181 (6%)
Frame = +1
Query: 64 ILLPFLLTCAIASAAECENATSLSLMIDSLLAT---YDRESPPDSK-IVVNLTLHL---R 222
+LL + T SA S S +D L+ YD P+ K VN+T ++
Sbjct: 21 LLLSLVATKETDSARSRSAPMSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINS 80
Query: 223 HANIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERLWRPDVVLLNAAATT 399
+I E+ R+ L+ W D RL+++ S + +W+PD+ N
Sbjct: 81 FGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGAN 140
Query: 400 AGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDXWPNDMQTCTFGFGSXMHNIDXMD 570
+ R+ NG+V + RL ++ M L +P D+QTC S + ++ +
Sbjct: 141 FHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFPMDVQTCIMQLESFGYTMNDLI 200
Query: 571 F 573
F
Sbjct: 201 F 201
>BC114947-1|AAI14948.1| 457|Homo sapiens GLRA1 protein protein.
Length = 457
Score = 42.3 bits (95), Expect = 0.002
Identities = 45/195 (23%), Positives = 84/195 (43%), Gaps = 17/195 (8%)
Frame = +1
Query: 40 HKMSTTYIILLPFLLTCAIASAAECENATSL------SLMIDSLLAT---YDRESPPDSK 192
+ +T + L ++ ++A++ E E A S S +D L+ YD P+ K
Sbjct: 2 YSFNTLRLYLWETIVFFSLAASKEAEAARSAPKPMSPSDFLDKLMGRTSGYDARIRPNFK 61
Query: 193 -IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERL 357
VN++ ++ +I E+ R+ L+ W D RL++N S + +
Sbjct: 62 GPPVNVSCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYNEYPDDSLDLDPSMLDSI 121
Query: 358 WRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDXWPNDMQTCT 528
W+PD+ N + R+S NG+V + R+ ++ M L +P D+QTC
Sbjct: 122 WKPDLFFANEKGAHFHEITTDNKLLRISRNGNVLYSIRITLTLACPMDLKNFPMDVQTCI 181
Query: 529 FGFGSXMHNIDXMDF 573
S + ++ + F
Sbjct: 182 MQLESFGYTMNDLIF 196
>BC074980-1|AAH74980.1| 449|Homo sapiens glycine receptor, alpha 1
(startle disease/hyperekplexia) protein.
Length = 449
Score = 42.3 bits (95), Expect = 0.002
Identities = 45/195 (23%), Positives = 84/195 (43%), Gaps = 17/195 (8%)
Frame = +1
Query: 40 HKMSTTYIILLPFLLTCAIASAAECENATSL------SLMIDSLLAT---YDRESPPDSK 192
+ +T + L ++ ++A++ E E A S S +D L+ YD P+ K
Sbjct: 2 YSFNTLRLYLWETIVFFSLAASKEAEAARSAPKPMSPSDFLDKLMGRTSGYDARIRPNFK 61
Query: 193 -IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERL 357
VN++ ++ +I E+ R+ L+ W D RL++N S + +
Sbjct: 62 GPPVNVSCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYNEYPDDSLDLDPSMLDSI 121
Query: 358 WRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDXWPNDMQTCT 528
W+PD+ N + R+S NG+V + R+ ++ M L +P D+QTC
Sbjct: 122 WKPDLFFANEKGAHFHEITTDNKLLRISRNGNVLYSIRITLTLACPMDLKNFPMDVQTCI 181
Query: 529 FGFGSXMHNIDXMDF 573
S + ++ + F
Sbjct: 182 MQLESFGYTMNDLIF 196
>BC036086-1|AAH36086.1| 464|Homo sapiens glycine receptor, alpha 3
protein.
Length = 464
Score = 42.3 bits (95), Expect = 0.002
Identities = 44/181 (24%), Positives = 75/181 (41%), Gaps = 11/181 (6%)
Frame = +1
Query: 64 ILLPFLLTCAIASAAECENATSLSLMIDSLLAT---YDRESPPDSK-IVVNLTLHL---R 222
+LL + T SA S S +D L+ YD P+ K VN+T ++
Sbjct: 21 LLLSLVATKETDSARSRSAPMSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINS 80
Query: 223 HANIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERLWRPDVVLLNAAATT 399
+I E+ R+ L+ W D RL+++ S + +W+PD+ N
Sbjct: 81 FGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGAN 140
Query: 400 AGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDXWPNDMQTCTFGFGSXMHNIDXMD 570
+ R+ NG+V + RL ++ M L +P D+QTC S + ++ +
Sbjct: 141 FHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFPMDVQTCIMQLESFGYTMNDLI 200
Query: 571 F 573
F
Sbjct: 201 F 201
>AF017724-1|AAC39919.1| 465|Homo sapiens glycine receptor alpha 3
subunit protein.
Length = 465
Score = 42.3 bits (95), Expect = 0.002
Identities = 44/181 (24%), Positives = 75/181 (41%), Gaps = 11/181 (6%)
Frame = +1
Query: 64 ILLPFLLTCAIASAAECENATSLSLMIDSLLAT---YDRESPPDSK-IVVNLTLHL---R 222
+LL + T SA S S +D L+ YD P+ K VN+T ++
Sbjct: 21 LLLSLVATKETDSARSRSAPMSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINS 80
Query: 223 HANIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERLWRPDVVLLNAAATT 399
+I E+ R+ L+ W D RL+++ S + +W+PD+ N
Sbjct: 81 FGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGAN 140
Query: 400 AGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDXWPNDMQTCTFGFGSXMHNIDXMD 570
+ R+ NG+V + RL ++ M L +P D+QTC S + ++ +
Sbjct: 141 FHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFPMDVQTCIMQLESFGYTMNDLI 200
Query: 571 F 573
F
Sbjct: 201 F 201
>X52009-1|CAA36258.1| 449|Homo sapiens inhibitory glycine receptor
protein.
Length = 449
Score = 41.9 bits (94), Expect = 0.003
Identities = 45/195 (23%), Positives = 84/195 (43%), Gaps = 17/195 (8%)
Frame = +1
Query: 40 HKMSTTYIILLPFLLTCAIASAAECENATSL------SLMIDSLLAT---YDRESPPDSK 192
+ +T + L ++ ++A++ E E A S S +D L+ YD P+ K
Sbjct: 2 YSFNTLRLYLSGAIVFFSLAASKEAEAARSATKPMSPSDFLDKLMGRTSGYDARIRPNFK 61
Query: 193 -IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERL 357
VN++ ++ +I E+ R+ L+ W D RL++N S + +
Sbjct: 62 GPPVNVSCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYNEYPDDSLDLDPSMLDSI 121
Query: 358 WRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDXWPNDMQTCT 528
W+PD+ N + R+S NG+V + R+ ++ M L +P D+QTC
Sbjct: 122 WKPDLFFANEKGAHFHEITTDNKLLRISRNGNVLYSIRITLTLACPMDLKNFPMDVQTCI 181
Query: 529 FGFGSXMHNIDXMDF 573
S + ++ + F
Sbjct: 182 MQLESFGYTMNDLIF 196
>U30461-1|AAB52519.1| 554|Homo sapiens GABAA receptor subunit
alpha4 protein.
Length = 554
Score = 41.5 bits (93), Expect = 0.004
Identities = 28/105 (26%), Positives = 45/105 (42%), Gaps = 3/105 (2%)
Frame = +1
Query: 238 ESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYAL 417
E E T+ + + WIDKRL ++ + ++W PD N + + +
Sbjct: 90 EMEYTMDVF--FRQTWIDKRLKYDGPIEILRLNNMMVTKVWTPDTFFRNGKKSVSHNMTA 147
Query: 418 RA---RVSNNGSVSWIKRLDISTPISMQLDXWPNDMQTCTFGFGS 543
R+ NG++ + RL IS M+L +P D C FGS
Sbjct: 148 PNKLFRIMRNGTILYTMRLTISAECPMRLVDFPMDGHACPLKFGS 192
>S81944-1|AAB36480.1| 453|Homo sapiens gamma-aminobutyric acid type
A receptor alpha 6 subunit protein.
Length = 453
Score = 41.5 bits (93), Expect = 0.004
Identities = 33/146 (22%), Positives = 60/146 (41%), Gaps = 7/146 (4%)
Frame = +1
Query: 127 SLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESESTVRILADLQMNWIDK 294
++S ++D+LL YD P + V +++ + + E + + W D+
Sbjct: 31 NVSRILDNLLEGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTDE 90
Query: 295 RLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRA---RVSNNGSVSWIKRL 465
RL + S + ++W PD N + A + R+ NG++ + RL
Sbjct: 91 RLKFGGPTEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTMRL 150
Query: 466 DISTPISMQLDXWPNDMQTCTFGFGS 543
I+ M+L +P D C FGS
Sbjct: 151 TINADCPMRLVNFPMDGHACPLKFGS 176
>BC099641-1|AAH99641.1| 453|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 6 protein.
Length = 453
Score = 41.5 bits (93), Expect = 0.004
Identities = 33/146 (22%), Positives = 60/146 (41%), Gaps = 7/146 (4%)
Frame = +1
Query: 127 SLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESESTVRILADLQMNWIDK 294
++S ++D+LL YD P + V +++ + + E + + W D+
Sbjct: 31 NVSRILDNLLEGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTDE 90
Query: 295 RLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRA---RVSNNGSVSWIKRL 465
RL + S + ++W PD N + A + R+ NG++ + RL
Sbjct: 91 RLKFGGPTEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTMRL 150
Query: 466 DISTPISMQLDXWPNDMQTCTFGFGS 543
I+ M+L +P D C FGS
Sbjct: 151 TINADCPMRLVNFPMDGHACPLKFGS 176
>BC099640-1|AAH99640.1| 453|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 6 protein.
Length = 453
Score = 41.5 bits (93), Expect = 0.004
Identities = 33/146 (22%), Positives = 60/146 (41%), Gaps = 7/146 (4%)
Frame = +1
Query: 127 SLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESESTVRILADLQMNWIDK 294
++S ++D+LL YD P + V +++ + + E + + W D+
Sbjct: 31 NVSRILDNLLEGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTDE 90
Query: 295 RLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRA---RVSNNGSVSWIKRL 465
RL + S + ++W PD N + A + R+ NG++ + RL
Sbjct: 91 RLKFGGPTEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTMRL 150
Query: 466 DISTPISMQLDXWPNDMQTCTFGFGS 543
I+ M+L +P D C FGS
Sbjct: 151 TINADCPMRLVNFPMDGHACPLKFGS 176
>BC096242-1|AAH96242.1| 453|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 6 protein.
Length = 453
Score = 41.5 bits (93), Expect = 0.004
Identities = 33/146 (22%), Positives = 60/146 (41%), Gaps = 7/146 (4%)
Frame = +1
Query: 127 SLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESESTVRILADLQMNWIDK 294
++S ++D+LL YD P + V +++ + + E + + W D+
Sbjct: 31 NVSRILDNLLEGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTDE 90
Query: 295 RLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRA---RVSNNGSVSWIKRL 465
RL + S + ++W PD N + A + R+ NG++ + RL
Sbjct: 91 RLKFGGPTEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTMRL 150
Query: 466 DISTPISMQLDXWPNDMQTCTFGFGS 543
I+ M+L +P D C FGS
Sbjct: 151 TINADCPMRLVNFPMDGHACPLKFGS 176
>BC096241-1|AAH96241.1| 453|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 6 protein.
Length = 453
Score = 41.5 bits (93), Expect = 0.004
Identities = 33/146 (22%), Positives = 60/146 (41%), Gaps = 7/146 (4%)
Frame = +1
Query: 127 SLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESESTVRILADLQMNWIDK 294
++S ++D+LL YD P + V +++ + + E + + W D+
Sbjct: 31 NVSRILDNLLEGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTDE 90
Query: 295 RLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRA---RVSNNGSVSWIKRL 465
RL + S + ++W PD N + A + R+ NG++ + RL
Sbjct: 91 RLKFGGPTEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTMRL 150
Query: 466 DISTPISMQLDXWPNDMQTCTFGFGS 543
I+ M+L +P D C FGS
Sbjct: 151 TINADCPMRLVNFPMDGHACPLKFGS 176
>BC035055-1|AAH35055.1| 554|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 4 protein.
Length = 554
Score = 41.5 bits (93), Expect = 0.004
Identities = 28/105 (26%), Positives = 45/105 (42%), Gaps = 3/105 (2%)
Frame = +1
Query: 238 ESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYAL 417
E E T+ + + WIDKRL ++ + ++W PD N + + +
Sbjct: 90 EMEYTMDVF--FRQTWIDKRLKYDGPIEILRLNNMMVTKVWTPDTFFRNGKKSVSHNMTA 147
Query: 418 RA---RVSNNGSVSWIKRLDISTPISMQLDXWPNDMQTCTFGFGS 543
R+ NG++ + RL IS M+L +P D C FGS
Sbjct: 148 PNKLFRIMRNGTILYTMRLTISAECPMRLVDFPMDGHACPLKFGS 192
>Z93848-1|CAI41994.1| 376|Homo sapiens glycine receptor, alpha 4
protein.
Length = 376
Score = 39.9 bits (89), Expect = 0.012
Identities = 36/145 (24%), Positives = 61/145 (42%), Gaps = 8/145 (5%)
Frame = +1
Query: 163 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 330
YD P+ K VN+T ++ ++I ++ R+ L+ W D RLS+
Sbjct: 17 YDARIRPNFKGPPVNVTCNIFINSFSSITKTTMDYRVNVFLRQQWNDPRLSYREYPDDSL 76
Query: 331 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLD 498
S + +W+PD+ N + R+ NG+V + RL + M L
Sbjct: 77 DLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLILSCLMDLK 136
Query: 499 XWPNDMQTCTFGFGSXMHNIDXMDF 573
+P D+QTCT S + + + F
Sbjct: 137 NFPMDIQTCTMQLESFGYTMKDLVF 161
>AL049610-1|CAI42158.1| 376|Homo sapiens glycine receptor, alpha 4
protein.
Length = 376
Score = 39.9 bits (89), Expect = 0.012
Identities = 36/145 (24%), Positives = 61/145 (42%), Gaps = 8/145 (5%)
Frame = +1
Query: 163 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 330
YD P+ K VN+T ++ ++I ++ R+ L+ W D RLS+
Sbjct: 17 YDARIRPNFKGPPVNVTCNIFINSFSSITKTTMDYRVNVFLRQQWNDPRLSYREYPDDSL 76
Query: 331 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLD 498
S + +W+PD+ N + R+ NG+V + RL + M L
Sbjct: 77 DLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLILSCLMDLK 136
Query: 499 XWPNDMQTCTFGFGSXMHNIDXMDF 573
+P D+QTCT S + + + F
Sbjct: 137 NFPMDIQTCTMQLESFGYTMKDLVF 161
>BC114967-1|AAI14968.1| 366|Homo sapiens GLRA1 protein protein.
Length = 366
Score = 38.7 bits (86), Expect = 0.027
Identities = 27/110 (24%), Positives = 48/110 (43%), Gaps = 4/110 (3%)
Frame = +1
Query: 256 RILADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERLWRPDVVLLNAAATTAGDYALR---A 423
R+ L+ W D RL++N S + +W+PD+ N +
Sbjct: 4 RVNIFLRQQWNDPRLAYNEYPDDSLDLDPSMLDSIWKPDLFFANEKGAHFHEITTDNKLL 63
Query: 424 RVSNNGSVSWIKRLDISTPISMQLDXWPNDMQTCTFGFGSXMHNIDXMDF 573
R+S NG+V + R+ ++ M L +P D+QTC S + ++ + F
Sbjct: 64 RISRNGNVLYSIRITLTLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIF 113
>AB209359-1|BAD92596.1| 533|Homo sapiens cholinergic receptor,
nicotinic, alpha polypeptide 4 precursor variant
protein.
Length = 533
Score = 34.7 bits (76), Expect = 0.44
Identities = 19/74 (25%), Positives = 32/74 (43%)
Frame = +1
Query: 355 LWRPDVVLLNAAATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDXWPNDMQTCTFG 534
LW +A A + +A + ++G V W + S+ + +P D Q CT
Sbjct: 25 LWLCCCTFTSADGDFAVTHLTKAHLFHDGRVQWTPPAIYKSSCSIDVTFFPFDQQNCTMK 84
Query: 535 FGSXMHNIDXMDFV 576
FGS ++ +D V
Sbjct: 85 FGSWTYDKAKIDLV 98
>BC096291-1|AAH96291.1| 556|Homo sapiens CHRNA4 protein protein.
Length = 556
Score = 33.9 bits (74), Expect = 0.78
Identities = 18/62 (29%), Positives = 31/62 (50%), Gaps = 4/62 (6%)
Frame = +1
Query: 403 GDYAL----RARVSNNGSVSWIKRLDISTPISMQLDXWPNDMQTCTFGFGSXMHNIDXMD 570
GD+A+ +A + ++G V W + S+ + +P D Q CT FGS ++ +D
Sbjct: 60 GDFAVTHLTKAHLFHDGRVQWTPPAIYKSSCSIDVTFFPFDQQNCTMKFGSWTYDKAKID 119
Query: 571 FV 576
V
Sbjct: 120 LV 121
>BC146774-1|AAI46775.1| 1114|Homo sapiens GPR124 protein protein.
Length = 1114
Score = 30.7 bits (66), Expect = 7.2
Identities = 16/55 (29%), Positives = 26/55 (47%), Gaps = 1/55 (1%)
Frame = +1
Query: 304 WNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNN-GSVSWIKRL 465
W +GEW C+ + + ++V+L T+ Y RV+NN G W + L
Sbjct: 314 WASGEWECTVSMAQGNASKKVEIVVLE----TSASYCPAERVANNRGDFRWPRTL 364
>AY181242-1|AAO27354.1| 1331|Homo sapiens G protein-coupled receptor
124 protein.
Length = 1331
Score = 30.7 bits (66), Expect = 7.2
Identities = 16/55 (29%), Positives = 26/55 (47%), Gaps = 1/55 (1%)
Frame = +1
Query: 304 WNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNN-GSVSWIKRL 465
W +GEW C+ + + ++V+L T+ Y RV+NN G W + L
Sbjct: 314 WASGEWECTVSMAQGNASKKVEIVVLE----TSASYCPAERVANNRGDFRWPRTL 364
>AK074099-1|BAB84925.1| 1310|Homo sapiens FLJ00170 protein protein.
Length = 1310
Score = 30.7 bits (66), Expect = 7.2
Identities = 16/55 (29%), Positives = 26/55 (47%), Gaps = 1/55 (1%)
Frame = +1
Query: 304 WNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNN-GSVSWIKRL 465
W +GEW C+ + + ++V+L T+ Y RV+NN G W + L
Sbjct: 293 WASGEWECTVSMAQGNASKKVEIVVLE----TSASYCPAERVANNRGDFRWPRTL 343
>AF378755-1|AAL11992.1| 1331|Homo sapiens tumor endothelial marker 5
precursor protein.
Length = 1331
Score = 30.7 bits (66), Expect = 7.2
Identities = 16/55 (29%), Positives = 26/55 (47%), Gaps = 1/55 (1%)
Frame = +1
Query: 304 WNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNN-GSVSWIKRL 465
W +GEW C+ + + ++V+L T+ Y RV+NN G W + L
Sbjct: 314 WASGEWECTVSMAQGNASKKVEIVVLE----TSASYCPAERVANNRGDFRWPRTL 364
>AB040964-1|BAA96055.2| 1206|Homo sapiens KIAA1531 protein protein.
Length = 1206
Score = 30.7 bits (66), Expect = 7.2
Identities = 16/55 (29%), Positives = 26/55 (47%), Gaps = 1/55 (1%)
Frame = +1
Query: 304 WNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNN-GSVSWIKRL 465
W +GEW C+ + + ++V+L T+ Y RV+NN G W + L
Sbjct: 406 WASGEWECTVSMAQGNASKKVEIVVLE----TSASYCPAERVANNRGDFRWPRTL 456
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 117,187,025
Number of Sequences: 237096
Number of extensions: 2679667
Number of successful extensions: 6218
Number of sequences better than 10.0: 173
Number of HSP's better than 10.0 without gapping: 5745
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 6081
length of database: 76,859,062
effective HSP length: 90
effective length of database: 55,520,422
effective search space used: 11159604822
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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