Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BmNP06_FL5_M12
(880 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
Y08417-1|CAA69694.1| 458|Homo sapiens nicotinic acetylcholine r... 63 1e-09
X67513-1|CAA47851.1| 423|Homo sapiens nicotinic acetylcholine ... 63 1e-09
U62438-1|AAB40116.1| 458|Homo sapiens nicotinic acetylcholine r... 63 1e-09
BC069788-1|AAH69788.1| 458|Homo sapiens cholinergic receptor, n... 63 1e-09
BC069703-1|AAH69703.1| 458|Homo sapiens cholinergic receptor, n... 63 1e-09
BC069681-1|AAH69681.1| 458|Homo sapiens cholinergic receptor, n... 63 1e-09
AJ306454-1|CAC34819.1| 497|Homo sapiens neuronal nicotinic acet... 63 1e-09
AF140765-1|AAD33063.1| 458|Homo sapiens neuronal acetylcholine ... 63 1e-09
Y08419-1|CAA69696.1| 468|Homo sapiens nicotinic acetylcholine r... 63 1e-09
U62434-1|AAB40112.1| 468|Homo sapiens nicotinic acetylcholine r... 63 1e-09
BC033639-1|AAH33639.1| 468|Homo sapiens cholinergic receptor, n... 63 1e-09
AJ306481-1|CAC34820.1| 468|Homo sapiens neuronal nicotinic acet... 63 1e-09
M83712-1|AAA58357.1| 468|Homo sapiens nicotinic receptor alpha ... 62 3e-09
Y16281-1|CAA76154.1| 529|Homo sapiens nicotinic acetylcholine r... 61 4e-09
Y08416-1|CAA69693.1| 498|Homo sapiens nicotinic acetylcholine r... 61 4e-09
U62439-1|AAB40117.1| 498|Homo sapiens nicotinic acetylcholine r... 61 4e-09
U62431-1|AAB40109.1| 529|Homo sapiens nicotinic acetylcholine r... 61 4e-09
U48861-1|AAA92123.1| 498|Homo sapiens beta 4 nicotinic acetylch... 61 4e-09
BC096082-1|AAH96082.1| 498|Homo sapiens cholinergic receptor, n... 61 4e-09
BC096080-1|AAH96080.1| 498|Homo sapiens cholinergic receptor, n... 61 4e-09
AF306329-1|AAL02062.1| 498|Homo sapiens neuronal nicotinic acet... 61 4e-09
Y08418-1|CAA69695.1| 503|Homo sapiens nicotinic acetylcholine r... 60 8e-09
X53559-1|CAA37625.1| 474|Homo sapiens neuronal nicotinic acetyl... 60 8e-09
U62432-1|AAB40110.1| 504|Homo sapiens nicotinic acetylcholine r... 60 8e-09
M37981-1|AAA59942.1| 503|Homo sapiens neuronal nicotinic acetyl... 60 8e-09
BT006897-1|AAP35543.1| 505|Homo sapiens cholinergic receptor, n... 60 8e-09
BT006646-1|AAP35292.1| 489|Homo sapiens cholinergic receptor, n... 60 8e-09
BC098443-1|AAH98443.1| 504|Homo sapiens cholinergic receptor, n... 60 8e-09
BC006114-1|AAH06114.1| 489|Homo sapiens CHRNA3 protein protein. 60 8e-09
BC002996-1|AAH02996.1| 505|Homo sapiens cholinergic receptor, n... 60 8e-09
BC001642-1|AAH01642.1| 505|Homo sapiens cholinergic receptor, n... 60 8e-09
BC000513-1|AAH00513.1| 505|Homo sapiens cholinergic receptor, n... 60 8e-09
AJ007783-1|CAA07682.1| 504|Homo sapiens nicotinic acetylcholine... 60 8e-09
AF385584-1|AAK68110.1| 489|Homo sapiens nicotinic cholinergic r... 60 8e-09
X68275-1|CAA48336.1| 451|Homo sapiens nicotinic receptor beta 4... 60 1e-08
M86383-1|AAC84176.1| 502|Homo sapiens nicotinic acetylcholine r... 58 4e-08
Y16282-1|CAA76155.1| 494|Homo sapiens nicotinic acetylcholine r... 58 6e-08
U62435-1|AAB40113.1| 494|Homo sapiens nicotinic acetylcholine r... 58 6e-08
BC014456-1|AAH14456.1| 494|Homo sapiens cholinergic receptor, n... 58 6e-08
AB079251-1|BAC06855.1| 494|Homo sapiens Nicotinic acetylcholine... 58 6e-08
Y08421-1|CAA69698.1| 627|Homo sapiens nicotinic acetylcholine r... 57 7e-08
X89741-1|CAA61893.1| 627|Homo sapiens neuronal acetylcholine re... 57 7e-08
X87629-1|CAA60959.1| 602|Homo sapiens nicotinic acetylcholine r... 57 7e-08
U62433-1|AAB40111.1| 627|Homo sapiens nicotinic acetylcholine r... 57 7e-08
L35901-1|AAA64743.1| 627|Homo sapiens nicotinic acetylcholine r... 57 7e-08
DQ093071-1|AAY88737.1| 627|Homo sapiens cholinergic receptor, n... 57 7e-08
BC096290-1|AAH96290.1| 627|Homo sapiens cholinergic receptor, n... 57 7e-08
X14830-1|CAA32939.1| 501|Homo sapiens protein ( Human mRNA for ... 57 1e-07
BC011371-1|AAH11371.1| 501|Homo sapiens cholinergic receptor, n... 57 1e-07
BC023553-1|AAH23553.1| 501|Homo sapiens cholinergic receptor, n... 56 2e-07
Y00762-1|CAA68731.1| 457|Homo sapiens protein ( Human mRNA for ... 55 3e-07
X02502-1|CAA26344.1| 457|Homo sapiens acetylcholine receptor pr... 55 3e-07
S77094-1|AAD14247.1| 457|Homo sapiens nicotinic acetylcholine r... 55 3e-07
BC006314-1|AAH06314.1| 269|Homo sapiens CHRNA1 protein protein. 55 3e-07
AC018890-1|AAY14687.1| 457|Homo sapiens unknown protein. 55 3e-07
X66403-1|CAA47030.1| 493|Homo sapiens acetylcholine receptor ep... 54 9e-07
AF105999-1|AAD24503.1| 493|Homo sapiens acetylcholine receptor ... 54 9e-07
Y08415-1|CAA69692.1| 502|Homo sapiens nicotinic acetylcholine r... 53 1e-06
X53179-1|CAA37320.1| 502|Homo sapiens precursor peptide (AA -25... 53 1e-06
U62437-1|AAB40115.1| 502|Homo sapiens nicotinic acetylcholine r... 53 1e-06
BC075041-1|AAH75041.1| 502|Homo sapiens cholinergic receptor, n... 53 1e-06
BC075040-1|AAH75040.1| 502|Homo sapiens cholinergic receptor, n... 53 1e-06
AL592078-3|CAI16184.1| 502|Homo sapiens cholinergic receptor, n... 53 1e-06
AJ001935-1|CAA05108.1| 504|Homo sapiens CHRNB2 protein. 53 1e-06
AF077186-1|AAD45422.1| 502|Homo sapiens neuronal nicotinic acet... 53 1e-06
DQ644022-1|ABG35128.1| 456|Homo sapiens 5-HT3 receptor subunit ... 52 2e-06
BC131799-1|AAI31800.1| 447|Homo sapiens 5-hydroxytryptamine (se... 52 2e-06
BC101185-1|AAI01186.1| 374|Homo sapiens HTR3E protein protein. 52 2e-06
BC101183-1|AAI01184.1| 471|Homo sapiens 5-hydroxytryptamine (se... 52 2e-06
BC101182-1|AAI01183.1| 471|Homo sapiens 5-hydroxytryptamine (se... 52 2e-06
AY159813-1|AAO38167.2| 471|Homo sapiens 5-hydroxytryptamine ser... 52 2e-06
AF459285-1|AAL66182.1| 447|Homo sapiens 5-hydroxytryptamine rec... 52 3e-06
X01715-1|CAA25861.1| 520|Homo sapiens acetylcholine receptor ga... 52 4e-06
AC092165-3|AAY24103.1| 520|Homo sapiens unknown protein. 52 4e-06
AY349353-1|AAQ93477.1| 456|Homo sapiens 5-HT3c1 serotonin recep... 50 8e-06
AY349352-1|AAQ93476.1| 441|Homo sapiens 5-HT3c1 serotonin recep... 50 8e-06
X55019-1|CAA38759.1| 517|Homo sapiens acetylcholine receptor de... 50 1e-05
BC093925-1|AAH93925.1| 517|Homo sapiens cholinergic receptor, n... 50 1e-05
BC093923-1|AAH93923.1| 517|Homo sapiens cholinergic receptor, n... 50 1e-05
AC092165-2|AAY24102.1| 517|Homo sapiens unknown protein. 50 1e-05
BC110597-1|AAI10598.1| 411|Homo sapiens ligand-gated ion channe... 50 1e-05
AK122638-1|BAC85499.1| 266|Homo sapiens yte protein of 76kDa) (... 50 1e-05
AF512521-1|AAO20969.1| 411|Homo sapiens ligand-gated ion channe... 50 1e-05
AB223030-1|BAE19924.1| 411|Homo sapiens ligand-gated ion-channe... 49 2e-05
BC113575-1|AAI13576.1| 479|Homo sapiens cholinergic receptor, n... 48 3e-05
BC113549-1|AAI13550.1| 479|Homo sapiens cholinergic receptor, n... 48 3e-05
BC111802-1|AAI11803.1| 465|Homo sapiens CHRNG protein protein. 48 3e-05
AY123244-1|AAM74523.1| 479|Homo sapiens nicotinic acetylcholine... 48 3e-05
AJ243342-1|CAB65091.1| 479|Homo sapiens nicotinic acetylcholine... 48 3e-05
AF227732-1|AAF61920.1| 470|Homo sapiens nicotinic acetylcholine... 48 3e-05
AC118275-1|AAY40986.1| 479|Homo sapiens unknown protein. 48 3e-05
Z23141-1|CAA80672.1| 479|Homo sapiens cholinergic receptor, nic... 47 8e-05
Y08420-1|CAA69697.1| 502|Homo sapiens nicotinic acetylcholine r... 47 8e-05
X70297-1|CAA49778.1| 502|Homo sapiens neuronal nicotinic acetyl... 47 8e-05
U62436-1|AAB40114.1| 502|Homo sapiens nicotinic acetylcholine r... 47 8e-05
AJ586911-1|CAE52911.1| 502|Homo sapiens nicotinic acetylcholine... 47 8e-05
U40583-1|AAA83561.1| 502|Homo sapiens alpha 7 neuronal nicotini... 46 2e-04
L08485-1|AAA58490.1| 462|Homo sapiens GABA-benzodiazepine recep... 46 2e-04
BT009830-1|AAP88832.1| 462|Homo sapiens gamma-aminobutyric acid... 46 2e-04
BC113422-1|AAI13423.1| 462|Homo sapiens gamma-aminobutyric acid... 46 2e-04
BC111979-1|AAI11980.1| 462|Homo sapiens gamma-aminobutyric acid... 46 2e-04
AJ295237-1|CAC16144.1| 450|Homo sapiens neuronal nicotinic acet... 46 2e-04
AJ278118-1|CAC20435.1| 450|Homo sapiens neuronal nicotinic acet... 46 2e-04
AF385585-1|AAK68111.1| 502|Homo sapiens nicotinic cholinergic r... 46 2e-04
AF327367-1|AAK14333.1| 450|Homo sapiens nicotinic acetylcholine... 46 2e-04
AF199235-1|AAG00795.2| 450|Homo sapiens nicotinic acetylcholine... 46 2e-04
U77731-2|AAB38273.1| 360|Homo sapiens glycine receptor alpha 2B... 45 3e-04
CR450343-1|CAG29339.1| 452|Homo sapiens GLRA2 protein. 45 3e-04
AY437084-1|AAR87843.1| 452|Homo sapiens glycine receptor alpha2... 45 3e-04
X52008-1|CAA36257.1| 452|Homo sapiens inhibitory glycine recept... 45 4e-04
U77731-1|AAB38272.1| 360|Homo sapiens glycine receptor alpha 2 ... 45 4e-04
BC032864-1|AAH32864.1| 452|Homo sapiens glycine receptor, alpha... 45 4e-04
AY437083-1|AAR87842.1| 452|Homo sapiens glycine receptor alpha2... 45 4e-04
AF053495-1|AAC35290.1| 452|Homo sapiens glycine receptor alpha ... 45 4e-04
U30461-1|AAB52519.1| 554|Homo sapiens GABAA receptor subunit al... 44 6e-04
BC035055-1|AAH35055.1| 554|Homo sapiens gamma-aminobutyric acid... 44 6e-04
S81944-1|AAB36480.1| 453|Homo sapiens gamma-aminobutyric acid t... 43 0.001
BC099641-1|AAH99641.1| 453|Homo sapiens gamma-aminobutyric acid... 43 0.001
BC099640-1|AAH99640.1| 453|Homo sapiens gamma-aminobutyric acid... 43 0.001
BC096242-1|AAH96242.1| 453|Homo sapiens gamma-aminobutyric acid... 43 0.001
BC096241-1|AAH96241.1| 453|Homo sapiens gamma-aminobutyric acid... 43 0.001
BC028629-1|AAH28629.1| 492|Homo sapiens gamma-aminobutyric acid... 42 0.002
S62908-1|AAB27279.1| 492|Homo sapiens gamma-aminobutyric acidA ... 42 0.003
BC096083-1|AAH96083.1| 198|Homo sapiens CHRNB4 protein protein. 42 0.003
BC096081-1|AAH96081.1| 198|Homo sapiens CHRNB4 protein protein. 42 0.003
AF166361-1|AAG12455.1| 492|Homo sapiens GABA receptor subunit a... 42 0.003
X52009-1|CAA36258.1| 449|Homo sapiens inhibitory glycine recept... 41 0.005
BC114947-1|AAI14948.1| 457|Homo sapiens GLRA1 protein protein. 41 0.005
BC074980-1|AAH74980.1| 449|Homo sapiens glycine receptor, alpha... 41 0.005
U95367-1|AAC51357.1| 440|Homo sapiens GABA-A receptor pi subuni... 40 0.016
BC109106-1|AAI09107.1| 440|Homo sapiens gamma-aminobutyric acid... 40 0.016
BC109105-1|AAI09106.1| 440|Homo sapiens gamma-aminobutyric acid... 40 0.016
BC074865-1|AAH74865.1| 440|Homo sapiens gamma-aminobutyric acid... 40 0.016
BC074810-1|AAH74810.1| 440|Homo sapiens gamma-aminobutyric acid... 40 0.016
AF009702-1|AAC24194.1| 440|Homo sapiens GABA-A receptor pi subu... 40 0.016
U93917-1|AAC39917.1| 449|Homo sapiens glycine receptor alpha 3 ... 39 0.027
BC114967-1|AAI14968.1| 366|Homo sapiens GLRA1 protein protein. 39 0.027
BC036086-1|AAH36086.1| 464|Homo sapiens glycine receptor, alpha... 39 0.027
AF017724-1|AAC39919.1| 465|Homo sapiens glycine receptor alpha ... 39 0.027
Z93848-1|CAI41994.1| 376|Homo sapiens glycine receptor, alpha 4... 38 0.048
BC074795-1|AAH74795.1| 467|Homo sapiens gamma-aminobutyric acid... 38 0.048
BC069348-1|AAH69348.1| 467|Homo sapiens gamma-aminobutyric acid... 38 0.048
BC059389-1|AAH59389.1| 475|Homo sapiens gamma-aminobutyric acid... 38 0.048
BC031087-1|AAH31087.1| 465|Homo sapiens gamma-aminobutyric acid... 38 0.048
AL049610-1|CAI42158.1| 376|Homo sapiens glycine receptor, alpha... 38 0.048
AF165124-1|AAD50273.1| 467|Homo sapiens gamma-aminobutyric acid... 38 0.048
X15376-1|CAA33437.1| 467|Homo sapiens GABA-A receptor gamma 2 s... 38 0.063
BC033801-1|AAH33801.1| 452|Homo sapiens gamma-aminobutyric acid... 36 0.15
AL391845-4|CAI15436.1| 452|Homo sapiens gamma-aminobutyric acid... 36 0.15
AF016917-1|AAB70007.1| 452|Homo sapiens GABA-A receptor delta s... 36 0.15
S82769-1|AAB39369.1| 467|Homo sapiens GABAA receptor gamma 3 su... 36 0.19
AF269144-1|AAF99698.1| 467|Homo sapiens GABAA receptor gamma 3 ... 36 0.19
AF228458-1|AAF63215.1| 449|Homo sapiens GABAA receptor gamma 3 ... 36 0.19
BC109211-1|AAI09212.1| 632|Homo sapiens gamma-aminobutyric acid... 34 0.59
BC109210-1|AAI09211.1| 632|Homo sapiens gamma-aminobutyric acid... 34 0.59
AF189259-1|AAF70380.1| 632|Homo sapiens GABA-A receptor theta s... 34 0.59
AF144648-1|AAD51172.1| 627|Homo sapiens GABA-A receptor theta p... 34 0.59
AB209359-1|BAD92596.1| 533|Homo sapiens cholinergic receptor, n... 33 1.4
BC096291-1|AAH96291.1| 556|Homo sapiens CHRNA4 protein protein. 32 2.4
>Y08417-1|CAA69694.1| 458|Homo sapiens nicotinic acetylcholine
receptor beta3 subunit precursor protein.
Length = 458
Score = 63.3 bits (147), Expect = 1e-09
Identities = 33/105 (31%), Positives = 51/105 (48%), Gaps = 2/105 (1%)
Frame = +2
Query: 254 LQMNWIDKRLXWNAGEWG-CXTWLVSSERLWRPDVVLL-NAAATTAGDYALRARVSNNGS 427
L+ W D +L WN ++G + V SE LW PD+VL NA G + V +NG+
Sbjct: 81 LKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFEGSLMTKVIVKSNGT 140
Query: 428 VSWIKRLDISTPISMQLDNWPNDMXTCTFKFGSXMXNIDXMDFVI 562
V W + +M + +P D C+ KFGS + +D ++
Sbjct: 141 VVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGTMVDLIL 185
>X67513-1|CAA47851.1| 423|Homo sapiens nicotinic acetylcholine
receptor beta-3 subunit protein.
Length = 423
Score = 63.3 bits (147), Expect = 1e-09
Identities = 33/105 (31%), Positives = 51/105 (48%), Gaps = 2/105 (1%)
Frame = +2
Query: 254 LQMNWIDKRLXWNAGEWG-CXTWLVSSERLWRPDVVLL-NAAATTAGDYALRARVSNNGS 427
L+ W D +L WN ++G + V SE LW PD+VL NA G + V +NG+
Sbjct: 46 LKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFEGSLMTKVIVKSNGT 105
Query: 428 VSWIKRLDISTPISMQLDNWPNDMXTCTFKFGSXMXNIDXMDFVI 562
V W + +M + +P D C+ KFGS + +D ++
Sbjct: 106 VVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGTMVDLIL 150
>U62438-1|AAB40116.1| 458|Homo sapiens nicotinic acetylcholine
receptor beta3 subunit precursor protein.
Length = 458
Score = 63.3 bits (147), Expect = 1e-09
Identities = 33/105 (31%), Positives = 51/105 (48%), Gaps = 2/105 (1%)
Frame = +2
Query: 254 LQMNWIDKRLXWNAGEWG-CXTWLVSSERLWRPDVVLL-NAAATTAGDYALRARVSNNGS 427
L+ W D +L WN ++G + V SE LW PD+VL NA G + V +NG+
Sbjct: 81 LKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFEGSLMTKVIVKSNGT 140
Query: 428 VSWIKRLDISTPISMQLDNWPNDMXTCTFKFGSXMXNIDXMDFVI 562
V W + +M + +P D C+ KFGS + +D ++
Sbjct: 141 VVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGTMVDLIL 185
>BC069788-1|AAH69788.1| 458|Homo sapiens cholinergic receptor,
nicotinic, beta 3 protein.
Length = 458
Score = 63.3 bits (147), Expect = 1e-09
Identities = 33/105 (31%), Positives = 51/105 (48%), Gaps = 2/105 (1%)
Frame = +2
Query: 254 LQMNWIDKRLXWNAGEWG-CXTWLVSSERLWRPDVVLL-NAAATTAGDYALRARVSNNGS 427
L+ W D +L WN ++G + V SE LW PD+VL NA G + V +NG+
Sbjct: 81 LKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFEGSLMTKVIVKSNGT 140
Query: 428 VSWIKRLDISTPISMQLDNWPNDMXTCTFKFGSXMXNIDXMDFVI 562
V W + +M + +P D C+ KFGS + +D ++
Sbjct: 141 VVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGTMVDLIL 185
>BC069703-1|AAH69703.1| 458|Homo sapiens cholinergic receptor,
nicotinic, beta 3 protein.
Length = 458
Score = 63.3 bits (147), Expect = 1e-09
Identities = 33/105 (31%), Positives = 51/105 (48%), Gaps = 2/105 (1%)
Frame = +2
Query: 254 LQMNWIDKRLXWNAGEWG-CXTWLVSSERLWRPDVVLL-NAAATTAGDYALRARVSNNGS 427
L+ W D +L WN ++G + V SE LW PD+VL NA G + V +NG+
Sbjct: 81 LKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFEGSLMTKVIVKSNGT 140
Query: 428 VSWIKRLDISTPISMQLDNWPNDMXTCTFKFGSXMXNIDXMDFVI 562
V W + +M + +P D C+ KFGS + +D ++
Sbjct: 141 VVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGTMVDLIL 185
>BC069681-1|AAH69681.1| 458|Homo sapiens cholinergic receptor,
nicotinic, beta 3 protein.
Length = 458
Score = 63.3 bits (147), Expect = 1e-09
Identities = 33/105 (31%), Positives = 51/105 (48%), Gaps = 2/105 (1%)
Frame = +2
Query: 254 LQMNWIDKRLXWNAGEWG-CXTWLVSSERLWRPDVVLL-NAAATTAGDYALRARVSNNGS 427
L+ W D +L WN ++G + V SE LW PD+VL NA G + V +NG+
Sbjct: 81 LKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFEGSLMTKVIVKSNGT 140
Query: 428 VSWIKRLDISTPISMQLDNWPNDMXTCTFKFGSXMXNIDXMDFVI 562
V W + +M + +P D C+ KFGS + +D ++
Sbjct: 141 VVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGTMVDLIL 185
>AJ306454-1|CAC34819.1| 497|Homo sapiens neuronal nicotinic
acetylcholine receptor beta-4 subunit protein.
Length = 497
Score = 63.3 bits (147), Expect = 1e-09
Identities = 37/131 (28%), Positives = 59/131 (45%), Gaps = 2/131 (1%)
Frame = +2
Query: 176 IVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLXWNAGEW-GCXTWLVSSERLWRP 349
I + L L L ++ E E + L+ W D RL WN+ + G + ++R+W P
Sbjct: 54 ISIKLQLSLAQLISVNEREQIMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLP 113
Query: 350 DVVLLNAAATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMXTCTFKFGSX 529
D+VL N T V +NGSV W+ + +++ +P D CT KF S
Sbjct: 114 DIVLYNNDGTYEVSVYTNLIVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRSW 173
Query: 530 MXNIDXMDFVI 562
+ +D V+
Sbjct: 174 TYDHTEIDMVL 184
>AF140765-1|AAD33063.1| 458|Homo sapiens neuronal acetylcholine
receptor beta-3 subunit precursor protein.
Length = 458
Score = 63.3 bits (147), Expect = 1e-09
Identities = 33/105 (31%), Positives = 51/105 (48%), Gaps = 2/105 (1%)
Frame = +2
Query: 254 LQMNWIDKRLXWNAGEWG-CXTWLVSSERLWRPDVVLL-NAAATTAGDYALRARVSNNGS 427
L+ W D +L WN ++G + V SE LW PD+VL NA G + V +NG+
Sbjct: 81 LKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFEGSLMTKVIVKSNGT 140
Query: 428 VSWIKRLDISTPISMQLDNWPNDMXTCTFKFGSXMXNIDXMDFVI 562
V W + +M + +P D C+ KFGS + +D ++
Sbjct: 141 VVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGTMVDLIL 185
>Y08419-1|CAA69696.1| 468|Homo sapiens nicotinic acetylcholine
receptor alpha5 subunit precursor protein.
Length = 468
Score = 62.9 bits (146), Expect = 1e-09
Identities = 33/135 (24%), Positives = 65/135 (48%), Gaps = 2/135 (1%)
Frame = +2
Query: 167 NSKIVVNLTLHLRH-ANIRESESTVRILADLQMNWIDKRLXWNAGEWGCXTWL-VSSERL 340
N KI + L + ++ E + L+ WID +L WN ++G + V S+ +
Sbjct: 69 NDKIKIKFGLAISQLVDVDEKNQLMTTNVWLKQEWIDVKLRWNPDDYGGIKVIRVPSDSV 128
Query: 341 WRPDVVLLNAAATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMXTCTFKF 520
W PD+VL + A + + + NG+V+W + + ++ + +P D+ C+ KF
Sbjct: 129 WTPDIVLFDNADGRFEGTSTKTVIRYNGTVTWTPPANYKSSCTIDVTFFPFDLQNCSMKF 188
Query: 521 GSXMXNIDXMDFVID 565
GS + +D +++
Sbjct: 189 GSWTYDGSQVDIILE 203
>U62434-1|AAB40112.1| 468|Homo sapiens nicotinic acetylcholine
receptor alpha5 subunit precursor protein.
Length = 468
Score = 62.9 bits (146), Expect = 1e-09
Identities = 33/135 (24%), Positives = 65/135 (48%), Gaps = 2/135 (1%)
Frame = +2
Query: 167 NSKIVVNLTLHLRH-ANIRESESTVRILADLQMNWIDKRLXWNAGEWGCXTWL-VSSERL 340
N KI + L + ++ E + L+ WID +L WN ++G + V S+ +
Sbjct: 69 NDKIKIKFGLAISQLVDVDEKNQLMTTNVWLKQEWIDVKLRWNPDDYGGIKVIRVPSDSV 128
Query: 341 WRPDVVLLNAAATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMXTCTFKF 520
W PD+VL + A + + + NG+V+W + + ++ + +P D+ C+ KF
Sbjct: 129 WTPDIVLFDNADGRFEGTSTKTVIRYNGTVTWTPPANYKSSCTIDVTFFPFDLQNCSMKF 188
Query: 521 GSXMXNIDXMDFVID 565
GS + +D +++
Sbjct: 189 GSWTYDGSQVDIILE 203
>BC033639-1|AAH33639.1| 468|Homo sapiens cholinergic receptor,
nicotinic, alpha 5 protein.
Length = 468
Score = 62.9 bits (146), Expect = 1e-09
Identities = 33/135 (24%), Positives = 65/135 (48%), Gaps = 2/135 (1%)
Frame = +2
Query: 167 NSKIVVNLTLHLRH-ANIRESESTVRILADLQMNWIDKRLXWNAGEWGCXTWL-VSSERL 340
N KI + L + ++ E + L+ WID +L WN ++G + V S+ +
Sbjct: 69 NDKIKIKFGLAISQLVDVDEKNQLMTTNVWLKQEWIDVKLRWNPDDYGGIKVIRVPSDSV 128
Query: 341 WRPDVVLLNAAATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMXTCTFKF 520
W PD+VL + A + + + NG+V+W + + ++ + +P D+ C+ KF
Sbjct: 129 WTPDIVLFDNADGRFEGTSTKTVIRYNGTVTWTPPANYKSSCTIDVTFFPFDLQNCSMKF 188
Query: 521 GSXMXNIDXMDFVID 565
GS + +D +++
Sbjct: 189 GSWTYDGSQVDIILE 203
>AJ306481-1|CAC34820.1| 468|Homo sapiens neuronal nicotinic
acetylcholine receptor alpha-5subunit protein.
Length = 468
Score = 62.9 bits (146), Expect = 1e-09
Identities = 33/135 (24%), Positives = 65/135 (48%), Gaps = 2/135 (1%)
Frame = +2
Query: 167 NSKIVVNLTLHLRH-ANIRESESTVRILADLQMNWIDKRLXWNAGEWGCXTWL-VSSERL 340
N KI + L + ++ E + L+ WID +L WN ++G + V S+ +
Sbjct: 69 NDKIKIKFGLAISQLVDVDEKNQLMTTNVWLKQEWIDVKLRWNPDDYGGIKVIRVPSDSV 128
Query: 341 WRPDVVLLNAAATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMXTCTFKF 520
W PD+VL + A + + + NG+V+W + + ++ + +P D+ C+ KF
Sbjct: 129 WTPDIVLFDNADGRFEGTSTKTVIRYNGTVTWTPPANYKSSCTIDVTFFPFDLQNCSMKF 188
Query: 521 GSXMXNIDXMDFVID 565
GS + +D +++
Sbjct: 189 GSWTYDGSQVDIILE 203
>M83712-1|AAA58357.1| 468|Homo sapiens nicotinic receptor alpha 5
subunit protein.
Length = 468
Score = 61.7 bits (143), Expect = 3e-09
Identities = 33/135 (24%), Positives = 64/135 (47%), Gaps = 2/135 (1%)
Frame = +2
Query: 167 NSKIVVNLTLHLRH-ANIRESESTVRILADLQMNWIDKRLXWNAGEWGCXTWL-VSSERL 340
N KI + L + ++ E + L+ WID +L WN ++G + V S+
Sbjct: 69 NDKIKIKFGLAISQLVDVDEKNQLMTTNVWLKQEWIDVKLRWNPDDYGGIKVIRVPSDSS 128
Query: 341 WRPDVVLLNAAATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMXTCTFKF 520
W PD+VL + A + + + NG+V+W + + ++ + +P D+ C+ KF
Sbjct: 129 WTPDIVLFDNADGRFEGTSTKTVIRYNGTVTWTPPANYKSSCTIDVTFFPFDLQNCSMKF 188
Query: 521 GSXMXNIDXMDFVID 565
GS + +D +++
Sbjct: 189 GSWTYDGSQVDIILE 203
>Y16281-1|CAA76154.1| 529|Homo sapiens nicotinic acetylcholine
receptor alpha2 subunit precursor protein.
Length = 529
Score = 61.3 bits (142), Expect = 4e-09
Identities = 38/126 (30%), Positives = 62/126 (49%), Gaps = 5/126 (3%)
Frame = +2
Query: 164 PNSKIVVNLTLHLRHANIRESESTVRILAD---LQMNWIDKRLXWNAGEWGCXTWL-VSS 331
PN+ VV + L A + + + +++ L+ W D +L WN ++G T L V S
Sbjct: 78 PNTSDVVIVRFGLSIAQLIDVDEKNQMMTTNVWLKQEWSDYKLRWNPADFGNITSLRVPS 137
Query: 332 ERLWRPDVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMXTC 508
E +W PD+VL N A A + +A + + G+V W+ + S+ + +P D C
Sbjct: 138 EMIWIPDIVLYNNADGEFAVTHMTKAHLFSTGTVHWVPPAIYKSSCSIDVTFFPFDQQNC 197
Query: 509 TFKFGS 526
KFGS
Sbjct: 198 KMKFGS 203
>Y08416-1|CAA69693.1| 498|Homo sapiens nicotinic acetylcholine
receptor beta4 subunit precursor protein.
Length = 498
Score = 61.3 bits (142), Expect = 4e-09
Identities = 38/132 (28%), Positives = 60/132 (45%), Gaps = 3/132 (2%)
Frame = +2
Query: 176 IVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLXWNAGEW-GCXTWLVSSERLWRP 349
I + L L L ++ E E + L+ W D RL WN+ + G + ++R+W P
Sbjct: 54 ISIKLQLSLAQLISVNEREQIMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLP 113
Query: 350 DVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMXTCTFKFGS 526
D+VL N A T V +NGSV W+ + +++ +P D CT KF S
Sbjct: 114 DIVLYNNADGTYEVSVYTNLIVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRS 173
Query: 527 XMXNIDXMDFVI 562
+ +D V+
Sbjct: 174 WTYDHTEIDMVL 185
>U62439-1|AAB40117.1| 498|Homo sapiens nicotinic acetylcholine
receptor beta4 subunit precursor protein.
Length = 498
Score = 61.3 bits (142), Expect = 4e-09
Identities = 38/132 (28%), Positives = 60/132 (45%), Gaps = 3/132 (2%)
Frame = +2
Query: 176 IVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLXWNAGEW-GCXTWLVSSERLWRP 349
I + L L L ++ E E + L+ W D RL WN+ + G + ++R+W P
Sbjct: 54 ISIKLQLSLAQLISVNEREQIMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLP 113
Query: 350 DVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMXTCTFKFGS 526
D+VL N A T V +NGSV W+ + +++ +P D CT KF S
Sbjct: 114 DIVLYNNADGTYEVSVYTNLIVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRS 173
Query: 527 XMXNIDXMDFVI 562
+ +D V+
Sbjct: 174 WTYDHTEIDMVL 185
>U62431-1|AAB40109.1| 529|Homo sapiens nicotinic acetylcholine
receptor alpha2 subunit precursor protein.
Length = 529
Score = 61.3 bits (142), Expect = 4e-09
Identities = 38/126 (30%), Positives = 62/126 (49%), Gaps = 5/126 (3%)
Frame = +2
Query: 164 PNSKIVVNLTLHLRHANIRESESTVRILAD---LQMNWIDKRLXWNAGEWGCXTWL-VSS 331
PN+ VV + L A + + + +++ L+ W D +L WN ++G T L V S
Sbjct: 78 PNTSDVVIVRFGLSIAQLIDVDEKNQMMTTNVWLKQEWSDYKLRWNPADFGNITSLRVPS 137
Query: 332 ERLWRPDVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMXTC 508
E +W PD+VL N A A + +A + + G+V W+ + S+ + +P D C
Sbjct: 138 EMIWIPDIVLYNNADGEFAVTHMTKAHLFSTGTVHWVPPAIYKSSCSIDVTFFPFDQQNC 197
Query: 509 TFKFGS 526
KFGS
Sbjct: 198 KMKFGS 203
>U48861-1|AAA92123.1| 498|Homo sapiens beta 4 nicotinic
acetylcholine receptor subunit protein.
Length = 498
Score = 61.3 bits (142), Expect = 4e-09
Identities = 38/132 (28%), Positives = 60/132 (45%), Gaps = 3/132 (2%)
Frame = +2
Query: 176 IVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLXWNAGEW-GCXTWLVSSERLWRP 349
I + L L L ++ E E + L+ W D RL WN+ + G + ++R+W P
Sbjct: 54 ISIKLQLSLAQLISVNEREQIMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLP 113
Query: 350 DVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMXTCTFKFGS 526
D+VL N A T V +NGSV W+ + +++ +P D CT KF S
Sbjct: 114 DIVLYNNADGTYEVSVYTNLIVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRS 173
Query: 527 XMXNIDXMDFVI 562
+ +D V+
Sbjct: 174 WTYDHTEIDMVL 185
>BC096082-1|AAH96082.1| 498|Homo sapiens cholinergic receptor,
nicotinic, beta 4 protein.
Length = 498
Score = 61.3 bits (142), Expect = 4e-09
Identities = 38/132 (28%), Positives = 60/132 (45%), Gaps = 3/132 (2%)
Frame = +2
Query: 176 IVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLXWNAGEW-GCXTWLVSSERLWRP 349
I + L L L ++ E E + L+ W D RL WN+ + G + ++R+W P
Sbjct: 54 ISIKLQLSLAQLISVNEREQIMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLP 113
Query: 350 DVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMXTCTFKFGS 526
D+VL N A T V +NGSV W+ + +++ +P D CT KF S
Sbjct: 114 DIVLYNNADGTYEVSVYTNLIVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRS 173
Query: 527 XMXNIDXMDFVI 562
+ +D V+
Sbjct: 174 WTYDHTEIDMVL 185
>BC096080-1|AAH96080.1| 498|Homo sapiens cholinergic receptor,
nicotinic, beta 4 protein.
Length = 498
Score = 61.3 bits (142), Expect = 4e-09
Identities = 38/132 (28%), Positives = 60/132 (45%), Gaps = 3/132 (2%)
Frame = +2
Query: 176 IVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLXWNAGEW-GCXTWLVSSERLWRP 349
I + L L L ++ E E + L+ W D RL WN+ + G + ++R+W P
Sbjct: 54 ISIKLQLSLAQLISVNEREQIMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLP 113
Query: 350 DVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMXTCTFKFGS 526
D+VL N A T V +NGSV W+ + +++ +P D CT KF S
Sbjct: 114 DIVLYNNADGTYEVSVYTNLIVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRS 173
Query: 527 XMXNIDXMDFVI 562
+ +D V+
Sbjct: 174 WTYDHTEIDMVL 185
>AF306329-1|AAL02062.1| 498|Homo sapiens neuronal nicotinic
acetylcholine receptor beta 4 subunit protein.
Length = 498
Score = 61.3 bits (142), Expect = 4e-09
Identities = 38/132 (28%), Positives = 60/132 (45%), Gaps = 3/132 (2%)
Frame = +2
Query: 176 IVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLXWNAGEW-GCXTWLVSSERLWRP 349
I + L L L ++ E E + L+ W D RL WN+ + G + ++R+W P
Sbjct: 54 ISIKLQLSLAQLISVNEREQIMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLP 113
Query: 350 DVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMXTCTFKFGS 526
D+VL N A T V +NGSV W+ + +++ +P D CT KF S
Sbjct: 114 DIVLYNNADGTYEVSVYTNLIVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRS 173
Query: 527 XMXNIDXMDFVI 562
+ +D V+
Sbjct: 174 WTYDHTEIDMVL 185
>Y08418-1|CAA69695.1| 503|Homo sapiens nicotinic acetylcholine
receptor alpha3 subunit precursor protein.
Length = 503
Score = 60.5 bits (140), Expect = 8e-09
Identities = 31/105 (29%), Positives = 53/105 (50%), Gaps = 2/105 (1%)
Frame = +2
Query: 254 LQMNWIDKRLXWNAGEWGCXTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 427
L+ W D +L WN ++G ++ V ++++W+PD+VL N A D +A + G
Sbjct: 85 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 144
Query: 428 VSWIKRLDISTPISMQLDNWPNDMXTCTFKFGSXMXNIDXMDFVI 562
V+WI + + + +P D CT KFGS + +D V+
Sbjct: 145 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVL 189
>X53559-1|CAA37625.1| 474|Homo sapiens neuronal nicotinic
acetylcholine receptor alpha-3merase protein.
Length = 474
Score = 60.5 bits (140), Expect = 8e-09
Identities = 31/105 (29%), Positives = 53/105 (50%), Gaps = 2/105 (1%)
Frame = +2
Query: 254 LQMNWIDKRLXWNAGEWGCXTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 427
L+ W D +L WN ++G ++ V ++++W+PD+VL N A D +A + G
Sbjct: 56 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 115
Query: 428 VSWIKRLDISTPISMQLDNWPNDMXTCTFKFGSXMXNIDXMDFVI 562
V+WI + + + +P D CT KFGS + +D V+
Sbjct: 116 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVL 160
>U62432-1|AAB40110.1| 504|Homo sapiens nicotinic acetylcholine
receptor alpha3 subunit precursor protein.
Length = 504
Score = 60.5 bits (140), Expect = 8e-09
Identities = 31/105 (29%), Positives = 53/105 (50%), Gaps = 2/105 (1%)
Frame = +2
Query: 254 LQMNWIDKRLXWNAGEWGCXTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 427
L+ W D +L WN ++G ++ V ++++W+PD+VL N A D +A + G
Sbjct: 86 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 145
Query: 428 VSWIKRLDISTPISMQLDNWPNDMXTCTFKFGSXMXNIDXMDFVI 562
V+WI + + + +P D CT KFGS + +D V+
Sbjct: 146 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVL 190
>M37981-1|AAA59942.1| 503|Homo sapiens neuronal nicotinic
acetylcholine receptor protein.
Length = 503
Score = 60.5 bits (140), Expect = 8e-09
Identities = 31/105 (29%), Positives = 53/105 (50%), Gaps = 2/105 (1%)
Frame = +2
Query: 254 LQMNWIDKRLXWNAGEWGCXTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 427
L+ W D +L WN ++G ++ V ++++W+PD+VL N A D +A + G
Sbjct: 85 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 144
Query: 428 VSWIKRLDISTPISMQLDNWPNDMXTCTFKFGSXMXNIDXMDFVI 562
V+WI + + + +P D CT KFGS + +D V+
Sbjct: 145 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVL 189
>BT006897-1|AAP35543.1| 505|Homo sapiens cholinergic receptor,
nicotinic, alpha polypeptide 3 protein.
Length = 505
Score = 60.5 bits (140), Expect = 8e-09
Identities = 31/105 (29%), Positives = 53/105 (50%), Gaps = 2/105 (1%)
Frame = +2
Query: 254 LQMNWIDKRLXWNAGEWGCXTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 427
L+ W D +L WN ++G ++ V ++++W+PD+VL N A D +A + G
Sbjct: 87 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 146
Query: 428 VSWIKRLDISTPISMQLDNWPNDMXTCTFKFGSXMXNIDXMDFVI 562
V+WI + + + +P D CT KFGS + +D V+
Sbjct: 147 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVL 191
>BT006646-1|AAP35292.1| 489|Homo sapiens cholinergic receptor,
nicotinic, alpha polypeptide 3 protein.
Length = 489
Score = 60.5 bits (140), Expect = 8e-09
Identities = 31/105 (29%), Positives = 53/105 (50%), Gaps = 2/105 (1%)
Frame = +2
Query: 254 LQMNWIDKRLXWNAGEWGCXTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 427
L+ W D +L WN ++G ++ V ++++W+PD+VL N A D +A + G
Sbjct: 87 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 146
Query: 428 VSWIKRLDISTPISMQLDNWPNDMXTCTFKFGSXMXNIDXMDFVI 562
V+WI + + + +P D CT KFGS + +D V+
Sbjct: 147 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVL 191
>BC098443-1|AAH98443.1| 504|Homo sapiens cholinergic receptor,
nicotinic, alpha 3 protein.
Length = 504
Score = 60.5 bits (140), Expect = 8e-09
Identities = 31/105 (29%), Positives = 53/105 (50%), Gaps = 2/105 (1%)
Frame = +2
Query: 254 LQMNWIDKRLXWNAGEWGCXTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 427
L+ W D +L WN ++G ++ V ++++W+PD+VL N A D +A + G
Sbjct: 86 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 145
Query: 428 VSWIKRLDISTPISMQLDNWPNDMXTCTFKFGSXMXNIDXMDFVI 562
V+WI + + + +P D CT KFGS + +D V+
Sbjct: 146 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVL 190
>BC006114-1|AAH06114.1| 489|Homo sapiens CHRNA3 protein protein.
Length = 489
Score = 60.5 bits (140), Expect = 8e-09
Identities = 31/105 (29%), Positives = 53/105 (50%), Gaps = 2/105 (1%)
Frame = +2
Query: 254 LQMNWIDKRLXWNAGEWGCXTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 427
L+ W D +L WN ++G ++ V ++++W+PD+VL N A D +A + G
Sbjct: 87 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 146
Query: 428 VSWIKRLDISTPISMQLDNWPNDMXTCTFKFGSXMXNIDXMDFVI 562
V+WI + + + +P D CT KFGS + +D V+
Sbjct: 147 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVL 191
>BC002996-1|AAH02996.1| 505|Homo sapiens cholinergic receptor,
nicotinic, alpha 3 protein.
Length = 505
Score = 60.5 bits (140), Expect = 8e-09
Identities = 31/105 (29%), Positives = 53/105 (50%), Gaps = 2/105 (1%)
Frame = +2
Query: 254 LQMNWIDKRLXWNAGEWGCXTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 427
L+ W D +L WN ++G ++ V ++++W+PD+VL N A D +A + G
Sbjct: 87 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 146
Query: 428 VSWIKRLDISTPISMQLDNWPNDMXTCTFKFGSXMXNIDXMDFVI 562
V+WI + + + +P D CT KFGS + +D V+
Sbjct: 147 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVL 191
>BC001642-1|AAH01642.1| 505|Homo sapiens cholinergic receptor,
nicotinic, alpha 3 protein.
Length = 505
Score = 60.5 bits (140), Expect = 8e-09
Identities = 31/105 (29%), Positives = 53/105 (50%), Gaps = 2/105 (1%)
Frame = +2
Query: 254 LQMNWIDKRLXWNAGEWGCXTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 427
L+ W D +L WN ++G ++ V ++++W+PD+VL N A D +A + G
Sbjct: 87 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 146
Query: 428 VSWIKRLDISTPISMQLDNWPNDMXTCTFKFGSXMXNIDXMDFVI 562
V+WI + + + +P D CT KFGS + +D V+
Sbjct: 147 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVL 191
>BC000513-1|AAH00513.1| 505|Homo sapiens cholinergic receptor,
nicotinic, alpha 3 protein.
Length = 505
Score = 60.5 bits (140), Expect = 8e-09
Identities = 31/105 (29%), Positives = 53/105 (50%), Gaps = 2/105 (1%)
Frame = +2
Query: 254 LQMNWIDKRLXWNAGEWGCXTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 427
L+ W D +L WN ++G ++ V ++++W+PD+VL N A D +A + G
Sbjct: 87 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 146
Query: 428 VSWIKRLDISTPISMQLDNWPNDMXTCTFKFGSXMXNIDXMDFVI 562
V+WI + + + +P D CT KFGS + +D V+
Sbjct: 147 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVL 191
>AJ007783-1|CAA07682.1| 504|Homo sapiens nicotinic acetylcholine
receptor alpha-3 subunit protein.
Length = 504
Score = 60.5 bits (140), Expect = 8e-09
Identities = 31/105 (29%), Positives = 53/105 (50%), Gaps = 2/105 (1%)
Frame = +2
Query: 254 LQMNWIDKRLXWNAGEWGCXTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 427
L+ W D +L WN ++G ++ V ++++W+PD+VL N A D +A + G
Sbjct: 86 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 145
Query: 428 VSWIKRLDISTPISMQLDNWPNDMXTCTFKFGSXMXNIDXMDFVI 562
V+WI + + + +P D CT KFGS + +D V+
Sbjct: 146 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVL 190
>AF385584-1|AAK68110.1| 489|Homo sapiens nicotinic cholinergic
receptor alpha 3 protein.
Length = 489
Score = 60.5 bits (140), Expect = 8e-09
Identities = 31/105 (29%), Positives = 53/105 (50%), Gaps = 2/105 (1%)
Frame = +2
Query: 254 LQMNWIDKRLXWNAGEWGCXTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 427
L+ W D +L WN ++G ++ V ++++W+PD+VL N A D +A + G
Sbjct: 81 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 140
Query: 428 VSWIKRLDISTPISMQLDNWPNDMXTCTFKFGSXMXNIDXMDFVI 562
V+WI + + + +P D CT KFGS + +D V+
Sbjct: 141 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVL 185
>X68275-1|CAA48336.1| 451|Homo sapiens nicotinic receptor beta 4
subunit protein.
Length = 451
Score = 60.1 bits (139), Expect = 1e-08
Identities = 37/132 (28%), Positives = 60/132 (45%), Gaps = 3/132 (2%)
Frame = +2
Query: 176 IVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLXWNAGEW-GCXTWLVSSERLWRP 349
I + L L L ++ E + + L+ W D RL WN+ + G + ++R+W P
Sbjct: 7 ISIKLQLSLAQLISVNERDEIMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLP 66
Query: 350 DVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMXTCTFKFGS 526
D+VL N A T V +NGSV W+ + +++ +P D CT KF S
Sbjct: 67 DIVLYNNADGTYEVSVYTNLIVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRS 126
Query: 527 XMXNIDXMDFVI 562
+ +D V+
Sbjct: 127 WTYDHTEIDMVL 138
>M86383-1|AAC84176.1| 502|Homo sapiens nicotinic acetylcholine
receptor alpha 3 subunit precursor protein.
Length = 502
Score = 58.0 bits (134), Expect = 4e-08
Identities = 32/108 (29%), Positives = 55/108 (50%), Gaps = 5/108 (4%)
Frame = +2
Query: 254 LQMNWIDKRLXWNAGEWGCXTWL-VSSERLWRPDVVLLNAAATTAGDYAL----RARVSN 418
L+ W D +L WN +G ++ V ++++W+PD+VL N A GD+ + +A +
Sbjct: 84 LKQIWNDYKLKWNPSGYGGAEFMRVPAQKIWKPDIVLYNNAV---GDFQVTTKTKALLKY 140
Query: 419 NGSVSWIKRLDISTPISMQLDNWPNDMXTCTFKFGSXMXNIDXMDFVI 562
G V+WI + + + +P D CT KFGS + +D V+
Sbjct: 141 TGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVL 188
>Y16282-1|CAA76155.1| 494|Homo sapiens nicotinic acetylcholine
receptor alpha6 subunit precursor protein.
Length = 494
Score = 57.6 bits (133), Expect = 6e-08
Identities = 35/123 (28%), Positives = 60/123 (48%), Gaps = 5/123 (4%)
Frame = +2
Query: 209 ANIRESESTVRILADLQMNWIDKRLXWNAGEW-GCXTWLVSSERLWRPDVVLLNAAATTA 385
AN+ E + L+ W D +L W+ E+ G T V ++++W+PD+VL N A
Sbjct: 71 ANVDEVNQIMETNLWLRHIWNDYKLRWDPMEYDGIETLRVPADKIWKPDIVLYNNAV--- 127
Query: 386 GDYAL----RARVSNNGSVSWIKRLDISTPISMQLDNWPNDMXTCTFKFGSXMXNIDXMD 553
GD+ + +A + NG ++W + M + +P D C+ KFGS + +D
Sbjct: 128 GDFQVEGKTKALLKYNGMITWTPPAIFKSSCPMDITFFPFDHQNCSLKFGSWTYDKAEID 187
Query: 554 FVI 562
+I
Sbjct: 188 LLI 190
>U62435-1|AAB40113.1| 494|Homo sapiens nicotinic acetylcholine
receptor alpha6 subunit precursor protein.
Length = 494
Score = 57.6 bits (133), Expect = 6e-08
Identities = 35/123 (28%), Positives = 60/123 (48%), Gaps = 5/123 (4%)
Frame = +2
Query: 209 ANIRESESTVRILADLQMNWIDKRLXWNAGEW-GCXTWLVSSERLWRPDVVLLNAAATTA 385
AN+ E + L+ W D +L W+ E+ G T V ++++W+PD+VL N A
Sbjct: 71 ANVDEVNQIMETNLWLRHIWNDYKLRWDPMEYDGIETLRVPADKIWKPDIVLYNNAV--- 127
Query: 386 GDYAL----RARVSNNGSVSWIKRLDISTPISMQLDNWPNDMXTCTFKFGSXMXNIDXMD 553
GD+ + +A + NG ++W + M + +P D C+ KFGS + +D
Sbjct: 128 GDFQVEGKTKALLKYNGMITWTPPAIFKSSCPMDITFFPFDHQNCSLKFGSWTYDKAEID 187
Query: 554 FVI 562
+I
Sbjct: 188 LLI 190
>BC014456-1|AAH14456.1| 494|Homo sapiens cholinergic receptor,
nicotinic, alpha 6 protein.
Length = 494
Score = 57.6 bits (133), Expect = 6e-08
Identities = 35/123 (28%), Positives = 60/123 (48%), Gaps = 5/123 (4%)
Frame = +2
Query: 209 ANIRESESTVRILADLQMNWIDKRLXWNAGEW-GCXTWLVSSERLWRPDVVLLNAAATTA 385
AN+ E + L+ W D +L W+ E+ G T V ++++W+PD+VL N A
Sbjct: 71 ANVDEVNQIMETNLWLRHIWNDYKLRWDPMEYDGIETLRVPADKIWKPDIVLYNNAV--- 127
Query: 386 GDYAL----RARVSNNGSVSWIKRLDISTPISMQLDNWPNDMXTCTFKFGSXMXNIDXMD 553
GD+ + +A + NG ++W + M + +P D C+ KFGS + +D
Sbjct: 128 GDFQVEGKTKALLKYNGMITWTPPAIFKSSCPMDITFFPFDHQNCSLKFGSWTYDKAEID 187
Query: 554 FVI 562
+I
Sbjct: 188 LLI 190
>AB079251-1|BAC06855.1| 494|Homo sapiens Nicotinic acetylcholine
receptor alpha 6 protein.
Length = 494
Score = 57.6 bits (133), Expect = 6e-08
Identities = 35/123 (28%), Positives = 60/123 (48%), Gaps = 5/123 (4%)
Frame = +2
Query: 209 ANIRESESTVRILADLQMNWIDKRLXWNAGEW-GCXTWLVSSERLWRPDVVLLNAAATTA 385
AN+ E + L+ W D +L W+ E+ G T V ++++W+PD+VL N A
Sbjct: 71 ANVDEVNQIMETNLWLRHIWNDYKLRWDPMEYDGIETLRVPADKIWKPDIVLYNNAV--- 127
Query: 386 GDYAL----RARVSNNGSVSWIKRLDISTPISMQLDNWPNDMXTCTFKFGSXMXNIDXMD 553
GD+ + +A + NG ++W + M + +P D C+ KFGS + +D
Sbjct: 128 GDFQVEGKTKALLKYNGMITWTPPAIFKSSCPMDITFFPFDHQNCSLKFGSWTYDKAEID 187
Query: 554 FVI 562
+I
Sbjct: 188 LLI 190
>Y08421-1|CAA69698.1| 627|Homo sapiens nicotinic acetylcholine
receptor alpha4 subunit precursor protein.
Length = 627
Score = 57.2 bits (132), Expect = 7e-08
Identities = 33/107 (30%), Positives = 55/107 (51%), Gaps = 5/107 (4%)
Frame = +2
Query: 254 LQMNWIDKRLXWNAGEWGCXTWL-VSSERLWRPDVVLLNAAATTAGDYAL----RARVSN 418
++ W D +L W+ ++ T + + SE +WRPD+VL N A GD+A+ +A + +
Sbjct: 89 VKQEWHDYKLRWDPADYENVTSIRIPSELIWRPDIVLYNNAD---GDFAVTHLTKAHLFH 145
Query: 419 NGSVSWIKRLDISTPISMQLDNWPNDMXTCTFKFGSXMXNIDXMDFV 559
+G V W + S+ + +P D CT KFGS + +D V
Sbjct: 146 DGRVQWTPPAIYKSSCSIDVTFFPFDQQNCTMKFGSWTYDKAKIDLV 192
>X89741-1|CAA61893.1| 627|Homo sapiens neuronal acetylcholine
receptor alpha-4 subunit protein.
Length = 627
Score = 57.2 bits (132), Expect = 7e-08
Identities = 33/107 (30%), Positives = 55/107 (51%), Gaps = 5/107 (4%)
Frame = +2
Query: 254 LQMNWIDKRLXWNAGEWGCXTWL-VSSERLWRPDVVLLNAAATTAGDYAL----RARVSN 418
++ W D +L W+ ++ T + + SE +WRPD+VL N A GD+A+ +A + +
Sbjct: 89 VKQEWHDYKLRWDPADYENVTSIRIPSELIWRPDIVLYNNAD---GDFAVTHLTKAHLFH 145
Query: 419 NGSVSWIKRLDISTPISMQLDNWPNDMXTCTFKFGSXMXNIDXMDFV 559
+G V W + S+ + +P D CT KFGS + +D V
Sbjct: 146 DGRVQWTPPAIYKSSCSIDVTFFPFDQQNCTMKFGSWTYDKAKIDLV 192
>X87629-1|CAA60959.1| 602|Homo sapiens nicotinic acetylcholine
receptor protein.
Length = 602
Score = 57.2 bits (132), Expect = 7e-08
Identities = 33/107 (30%), Positives = 55/107 (51%), Gaps = 5/107 (4%)
Frame = +2
Query: 254 LQMNWIDKRLXWNAGEWGCXTWL-VSSERLWRPDVVLLNAAATTAGDYAL----RARVSN 418
++ W D +L W+ ++ T + + SE +WRPD+VL N A GD+A+ +A + +
Sbjct: 64 VKQEWHDYKLRWDPADYENVTSIRIPSELIWRPDIVLYNNAD---GDFAVTHLTKAHLFH 120
Query: 419 NGSVSWIKRLDISTPISMQLDNWPNDMXTCTFKFGSXMXNIDXMDFV 559
+G V W + S+ + +P D CT KFGS + +D V
Sbjct: 121 DGRVQWTPPAIYKSSCSIDVTFFPFDQQNCTMKFGSWTYDKAKIDLV 167
>U62433-1|AAB40111.1| 627|Homo sapiens nicotinic acetylcholine
receptor alpha4 subunit precursor protein.
Length = 627
Score = 57.2 bits (132), Expect = 7e-08
Identities = 33/107 (30%), Positives = 55/107 (51%), Gaps = 5/107 (4%)
Frame = +2
Query: 254 LQMNWIDKRLXWNAGEWGCXTWL-VSSERLWRPDVVLLNAAATTAGDYAL----RARVSN 418
++ W D +L W+ ++ T + + SE +WRPD+VL N A GD+A+ +A + +
Sbjct: 89 VKQEWHDYKLRWDPADYENVTSIRIPSELIWRPDIVLYNNAD---GDFAVTHLTKAHLFH 145
Query: 419 NGSVSWIKRLDISTPISMQLDNWPNDMXTCTFKFGSXMXNIDXMDFV 559
+G V W + S+ + +P D CT KFGS + +D V
Sbjct: 146 DGRVQWTPPAIYKSSCSIDVTFFPFDQQNCTMKFGSWTYDKAKIDLV 192
>L35901-1|AAA64743.1| 627|Homo sapiens nicotinic acetylcholine
receptor alpha 4 subunit protein.
Length = 627
Score = 57.2 bits (132), Expect = 7e-08
Identities = 33/107 (30%), Positives = 55/107 (51%), Gaps = 5/107 (4%)
Frame = +2
Query: 254 LQMNWIDKRLXWNAGEWGCXTWL-VSSERLWRPDVVLLNAAATTAGDYAL----RARVSN 418
++ W D +L W+ ++ T + + SE +WRPD+VL N A GD+A+ +A + +
Sbjct: 89 VKQEWHDYKLRWDPADYENVTSIRIPSELIWRPDIVLYNNAD---GDFAVTHLTKAHLFH 145
Query: 419 NGSVSWIKRLDISTPISMQLDNWPNDMXTCTFKFGSXMXNIDXMDFV 559
+G V W + S+ + +P D CT KFGS + +D V
Sbjct: 146 DGRVQWTPPAIYKSSCSIDVTFFPFDQQNCTMKFGSWTYDKAKIDLV 192
>DQ093071-1|AAY88737.1| 627|Homo sapiens cholinergic receptor,
nicotinic, alpha polypeptide 4 protein.
Length = 627
Score = 57.2 bits (132), Expect = 7e-08
Identities = 33/107 (30%), Positives = 55/107 (51%), Gaps = 5/107 (4%)
Frame = +2
Query: 254 LQMNWIDKRLXWNAGEWGCXTWL-VSSERLWRPDVVLLNAAATTAGDYAL----RARVSN 418
++ W D +L W+ ++ T + + SE +WRPD+VL N A GD+A+ +A + +
Sbjct: 89 VKQEWHDYKLRWDPADYENVTSIRIPSELIWRPDIVLYNNAD---GDFAVTHLTKAHLFH 145
Query: 419 NGSVSWIKRLDISTPISMQLDNWPNDMXTCTFKFGSXMXNIDXMDFV 559
+G V W + S+ + +P D CT KFGS + +D V
Sbjct: 146 DGRVQWTPPAIYKSSCSIDVTFFPFDQQNCTMKFGSWTYDKAKIDLV 192
>BC096290-1|AAH96290.1| 627|Homo sapiens cholinergic receptor,
nicotinic, alpha 4 protein.
Length = 627
Score = 57.2 bits (132), Expect = 7e-08
Identities = 33/107 (30%), Positives = 55/107 (51%), Gaps = 5/107 (4%)
Frame = +2
Query: 254 LQMNWIDKRLXWNAGEWGCXTWL-VSSERLWRPDVVLLNAAATTAGDYAL----RARVSN 418
++ W D +L W+ ++ T + + SE +WRPD+VL N A GD+A+ +A + +
Sbjct: 89 VKQEWHDYKLRWDPADYENVTSIRIPSELIWRPDIVLYNNAD---GDFAVTHLTKAHLFH 145
Query: 419 NGSVSWIKRLDISTPISMQLDNWPNDMXTCTFKFGSXMXNIDXMDFV 559
+G V W + S+ + +P D CT KFGS + +D V
Sbjct: 146 DGRVQWTPPAIYKSSCSIDVTFFPFDQQNCTMKFGSWTYDKAKIDLV 192
>X14830-1|CAA32939.1| 501|Homo sapiens protein ( Human mRNA for
muscle acetylcholine receptor beta-subunit. ).
Length = 501
Score = 56.8 bits (131), Expect = 1e-07
Identities = 44/135 (32%), Positives = 65/135 (48%), Gaps = 4/135 (2%)
Frame = +2
Query: 134 SSQRTIGSLPPNSKIVVNLTL-HLRHANIRESESTVRILADLQMNWIDKRLXWNAGEW-G 307
SS R + ++ V L L L N ++ E + ++ DL+ W D RL W+ E G
Sbjct: 40 SSVRPAREVGDRVRVSVGLILAQLISLNEKDEEMSTKVYLDLE--WTDYRLSWDPAEHDG 97
Query: 308 CXTWLVSSERLWRPDVVLLNAAATTAGDYAL--RARVSNNGSVSWIKRLDISTPISMQLD 481
+ +++E +W PDVVLLN D AL VS++GSV W + S+Q+
Sbjct: 98 IDSLRITAESVWLPDVVLLNNNDGNF-DVALDISVVVSSDGSVRWQPPGIYRSSCSIQVT 156
Query: 482 NWPNDMXTCTFKFGS 526
+P D CT F S
Sbjct: 157 YFPFDWQNCTMVFSS 171
>BC011371-1|AAH11371.1| 501|Homo sapiens cholinergic receptor,
nicotinic, beta 1 (muscle) protein.
Length = 501
Score = 56.8 bits (131), Expect = 1e-07
Identities = 44/135 (32%), Positives = 65/135 (48%), Gaps = 4/135 (2%)
Frame = +2
Query: 134 SSQRTIGSLPPNSKIVVNLTL-HLRHANIRESESTVRILADLQMNWIDKRLXWNAGEW-G 307
SS R + ++ V L L L N ++ E + ++ DL+ W D RL W+ E G
Sbjct: 40 SSVRPAREVGDRVRVSVGLILAQLISLNEKDEEMSTKVYLDLE--WTDYRLSWDPAEHDG 97
Query: 308 CXTWLVSSERLWRPDVVLLNAAATTAGDYAL--RARVSNNGSVSWIKRLDISTPISMQLD 481
+ +++E +W PDVVLLN D AL VS++GSV W + S+Q+
Sbjct: 98 IDSLRITAESVWLPDVVLLNNNDGNF-DVALDISVVVSSDGSVRWQPPGIYRSSCSIQVT 156
Query: 482 NWPNDMXTCTFKFGS 526
+P D CT F S
Sbjct: 157 YFPFDWQNCTMVFSS 171
>BC023553-1|AAH23553.1| 501|Homo sapiens cholinergic receptor,
nicotinic, beta 1 (muscle) protein.
Length = 501
Score = 55.6 bits (128), Expect = 2e-07
Identities = 42/137 (30%), Positives = 66/137 (48%), Gaps = 6/137 (4%)
Frame = +2
Query: 134 SSQRTIGSLPPNSKIVVNLTL-HLRHANIRESESTVRILADLQMNWIDKRLXWNAGEW-G 307
SS R + ++ V L L L N ++ E + ++ DL+ W D RL W+ E G
Sbjct: 40 SSVRPAREVGDRVRVSVGLILAQLISLNEKDEEMSTKVYLDLE--WTDYRLSWDPAEHDG 97
Query: 308 CXTWLVSSERLWRPDVVLLNAAATTAGDY----ALRARVSNNGSVSWIKRLDISTPISMQ 475
+ +++E +W PDVVLLN G++ + VS++GSV W + S+Q
Sbjct: 98 IDSLRITAESVWLPDVVLLN---NNDGNFYVALDISVVVSSDGSVRWQPPGIYRSSCSIQ 154
Query: 476 LDNWPNDMXTCTFKFGS 526
+ +P D CT F S
Sbjct: 155 VTYFPFDWQNCTMVFSS 171
>Y00762-1|CAA68731.1| 457|Homo sapiens protein ( Human mRNA for
muscle acetylcholine receptor alpha-subunit. ).
Length = 457
Score = 55.2 bits (127), Expect = 3e-07
Identities = 33/123 (26%), Positives = 60/123 (48%), Gaps = 5/123 (4%)
Frame = +2
Query: 173 KIVVNLTLHLRHANIRESESTVRILADLQMNWIDKRLXWNAGEWGCXTWL-VSSERLWRP 349
++ V L L ++ N+ E V L+ W+D L WN ++G + + SE++WRP
Sbjct: 50 EVTVGLQL-IQLINVDEVNQIVTTNVRLKQQWVDYNLKWNPDDYGGVKKIHIPSEKIWRP 108
Query: 350 DVVLLNAAATTAGDYAL----RARVSNNGSVSWIKRLDISTPISMQLDNWPNDMXTCTFK 517
D+VL N A GD+A+ + + G ++W + + + ++P D C+ K
Sbjct: 109 DLVLYNNA---DGDFAIVKFTKVLLQYTGHITWTPPAIFKSYCEIIVTHFPFDEQNCSMK 165
Query: 518 FGS 526
G+
Sbjct: 166 LGT 168
>X02502-1|CAA26344.1| 457|Homo sapiens acetylcholine receptor
protein.
Length = 457
Score = 55.2 bits (127), Expect = 3e-07
Identities = 33/123 (26%), Positives = 60/123 (48%), Gaps = 5/123 (4%)
Frame = +2
Query: 173 KIVVNLTLHLRHANIRESESTVRILADLQMNWIDKRLXWNAGEWGCXTWL-VSSERLWRP 349
++ V L L ++ N+ E V L+ W+D L WN ++G + + SE++WRP
Sbjct: 50 EVTVGLQL-IQLINVDEVNQIVTTNVRLKQQWVDYNLKWNPDDYGGVKKIHIPSEKIWRP 108
Query: 350 DVVLLNAAATTAGDYAL----RARVSNNGSVSWIKRLDISTPISMQLDNWPNDMXTCTFK 517
D+VL N A GD+A+ + + G ++W + + + ++P D C+ K
Sbjct: 109 DLVLYNNA---DGDFAIVKFTKVLLQYTGHITWTPPAIFKSYCEIIVTHFPFDEQNCSMK 165
Query: 518 FGS 526
G+
Sbjct: 166 LGT 168
>S77094-1|AAD14247.1| 457|Homo sapiens nicotinic acetylcholine
receptor alpha subunit|AChR protein.
Length = 457
Score = 55.2 bits (127), Expect = 3e-07
Identities = 33/123 (26%), Positives = 60/123 (48%), Gaps = 5/123 (4%)
Frame = +2
Query: 173 KIVVNLTLHLRHANIRESESTVRILADLQMNWIDKRLXWNAGEWGCXTWL-VSSERLWRP 349
++ V L L ++ N+ E V L+ W+D L WN ++G + + SE++WRP
Sbjct: 50 EVTVGLQL-IQLINVDEVNQIVTTNVRLKQQWVDYNLKWNPDDYGGVKKIHIPSEKIWRP 108
Query: 350 DVVLLNAAATTAGDYAL----RARVSNNGSVSWIKRLDISTPISMQLDNWPNDMXTCTFK 517
D+VL N A GD+A+ + + G ++W + + + ++P D C+ K
Sbjct: 109 DLVLYNNA---DGDFAIVKFTKVLLQYTGHITWTPPAIFKSYCEIIVTHFPFDEQNCSMK 165
Query: 518 FGS 526
G+
Sbjct: 166 LGT 168
>BC006314-1|AAH06314.1| 269|Homo sapiens CHRNA1 protein protein.
Length = 269
Score = 55.2 bits (127), Expect = 3e-07
Identities = 33/123 (26%), Positives = 60/123 (48%), Gaps = 5/123 (4%)
Frame = +2
Query: 173 KIVVNLTLHLRHANIRESESTVRILADLQMNWIDKRLXWNAGEWGCXTWL-VSSERLWRP 349
++ V L L ++ N+ E V L+ W+D L WN ++G + + SE++WRP
Sbjct: 50 EVTVGLQL-IQLINVDEVNQIVTTNVRLKQQWVDYNLKWNPDDYGGVKKIHIPSEKIWRP 108
Query: 350 DVVLLNAAATTAGDYAL----RARVSNNGSVSWIKRLDISTPISMQLDNWPNDMXTCTFK 517
D+VL N A GD+A+ + + G ++W + + + ++P D C+ K
Sbjct: 109 DLVLYNNA---DGDFAIVKFTKVLLQYTGHITWTPPAIFKSYCEIIVTHFPFDEQNCSMK 165
Query: 518 FGS 526
G+
Sbjct: 166 LGT 168
>AC018890-1|AAY14687.1| 457|Homo sapiens unknown protein.
Length = 457
Score = 55.2 bits (127), Expect = 3e-07
Identities = 33/123 (26%), Positives = 60/123 (48%), Gaps = 5/123 (4%)
Frame = +2
Query: 173 KIVVNLTLHLRHANIRESESTVRILADLQMNWIDKRLXWNAGEWGCXTWL-VSSERLWRP 349
++ V L L ++ N+ E V L+ W+D L WN ++G + + SE++WRP
Sbjct: 50 EVTVGLQL-IQLINVDEVNQIVTTNVRLKQQWVDYNLKWNPDDYGGVKKIHIPSEKIWRP 108
Query: 350 DVVLLNAAATTAGDYAL----RARVSNNGSVSWIKRLDISTPISMQLDNWPNDMXTCTFK 517
D+VL N A GD+A+ + + G ++W + + + ++P D C+ K
Sbjct: 109 DLVLYNNA---DGDFAIVKFTKVLLQYTGHITWTPPAIFKSYCEIIVTHFPFDEQNCSMK 165
Query: 518 FGS 526
G+
Sbjct: 166 LGT 168
>X66403-1|CAA47030.1| 493|Homo sapiens acetylcholine receptor
epsilon subunit CHRNE protein.
Length = 493
Score = 53.6 bits (123), Expect = 9e-07
Identities = 34/134 (25%), Positives = 64/134 (47%), Gaps = 3/134 (2%)
Frame = +2
Query: 164 PNSKIVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLXWNAGEWG-CXTWLVSSER 337
P + ++L + L + ++ E E T+ + ++W D RL ++ ++G T V SE
Sbjct: 45 PEDTVTISLKVTLTNLISLNEKEETLTTSVWIGIDWQDYRLNYSKDDFGGIETLRVPSEL 104
Query: 338 LWRPDVVLLNAAATTAG-DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMXTCTF 514
+W P++VL N G Y V GSV+W+ + ++++ +P D C+
Sbjct: 105 VWLPEIVLENNIDGQFGVAYDANVLVYEGGSVTWLPPAIYRSVCAVEVTYFPFDWQNCSL 164
Query: 515 KFGSXMXNIDXMDF 556
F S N + ++F
Sbjct: 165 IFRSQTYNAEEVEF 178
>AF105999-1|AAD24503.1| 493|Homo sapiens acetylcholine receptor
epsilon subunit protein.
Length = 493
Score = 53.6 bits (123), Expect = 9e-07
Identities = 34/134 (25%), Positives = 64/134 (47%), Gaps = 3/134 (2%)
Frame = +2
Query: 164 PNSKIVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLXWNAGEWG-CXTWLVSSER 337
P + ++L + L + ++ E E T+ + ++W D RL ++ ++G T V SE
Sbjct: 45 PEDTVTISLKVTLTNLISLNEKEETLTTSVWIGIDWQDYRLNYSKDDFGGIETLRVPSEL 104
Query: 338 LWRPDVVLLNAAATTAG-DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMXTCTF 514
+W P++VL N G Y V GSV+W+ + ++++ +P D C+
Sbjct: 105 VWLPEIVLENNIDGQFGVAYDANVLVYEGGSVTWLPPAIYRSVCAVEVTYFPFDWQNCSL 164
Query: 515 KFGSXMXNIDXMDF 556
F S N + ++F
Sbjct: 165 IFRSQTYNAEEVEF 178
>Y08415-1|CAA69692.1| 502|Homo sapiens nicotinic acetylcholine
receptor beta2 subunit precursor protein.
Length = 502
Score = 53.2 bits (122), Expect = 1e-06
Identities = 36/132 (27%), Positives = 59/132 (44%), Gaps = 3/132 (2%)
Frame = +2
Query: 176 IVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLXWNAGEWGCXTWL-VSSERLWRP 349
+ V L + L ++ E E + L W D RL W E+ + + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 350 DVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMXTCTFKFGS 526
DVVL N A + A VS +GS+ W+ + +++ ++P D CT KF S
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRS 175
Query: 527 XMXNIDXMDFVI 562
+ +D V+
Sbjct: 176 WTYDRTEIDLVL 187
>X53179-1|CAA37320.1| 502|Homo sapiens precursor peptide (AA -25 to
477) protein.
Length = 502
Score = 53.2 bits (122), Expect = 1e-06
Identities = 36/132 (27%), Positives = 59/132 (44%), Gaps = 3/132 (2%)
Frame = +2
Query: 176 IVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLXWNAGEWGCXTWL-VSSERLWRP 349
+ V L + L ++ E E + L W D RL W E+ + + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 350 DVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMXTCTFKFGS 526
DVVL N A + A VS +GS+ W+ + +++ ++P D CT KF S
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRS 175
Query: 527 XMXNIDXMDFVI 562
+ +D V+
Sbjct: 176 WTYDRTEIDLVL 187
>U62437-1|AAB40115.1| 502|Homo sapiens nicotinic acetylcholine
receptor beta2 subunit precursor protein.
Length = 502
Score = 53.2 bits (122), Expect = 1e-06
Identities = 36/132 (27%), Positives = 59/132 (44%), Gaps = 3/132 (2%)
Frame = +2
Query: 176 IVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLXWNAGEWGCXTWL-VSSERLWRP 349
+ V L + L ++ E E + L W D RL W E+ + + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 350 DVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMXTCTFKFGS 526
DVVL N A + A VS +GS+ W+ + +++ ++P D CT KF S
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRS 175
Query: 527 XMXNIDXMDFVI 562
+ +D V+
Sbjct: 176 WTYDRTEIDLVL 187
>BC075041-1|AAH75041.1| 502|Homo sapiens cholinergic receptor,
nicotinic, beta 2 (neuronal) protein.
Length = 502
Score = 53.2 bits (122), Expect = 1e-06
Identities = 36/132 (27%), Positives = 59/132 (44%), Gaps = 3/132 (2%)
Frame = +2
Query: 176 IVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLXWNAGEWGCXTWL-VSSERLWRP 349
+ V L + L ++ E E + L W D RL W E+ + + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 350 DVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMXTCTFKFGS 526
DVVL N A + A VS +GS+ W+ + +++ ++P D CT KF S
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRS 175
Query: 527 XMXNIDXMDFVI 562
+ +D V+
Sbjct: 176 WTYDRTEIDLVL 187
>BC075040-1|AAH75040.1| 502|Homo sapiens cholinergic receptor,
nicotinic, beta 2 (neuronal) protein.
Length = 502
Score = 53.2 bits (122), Expect = 1e-06
Identities = 36/132 (27%), Positives = 59/132 (44%), Gaps = 3/132 (2%)
Frame = +2
Query: 176 IVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLXWNAGEWGCXTWL-VSSERLWRP 349
+ V L + L ++ E E + L W D RL W E+ + + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 350 DVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMXTCTFKFGS 526
DVVL N A + A VS +GS+ W+ + +++ ++P D CT KF S
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRS 175
Query: 527 XMXNIDXMDFVI 562
+ +D V+
Sbjct: 176 WTYDRTEIDLVL 187
>AL592078-3|CAI16184.1| 502|Homo sapiens cholinergic receptor,
nicotinic, beta 2 (neuronal) protein.
Length = 502
Score = 53.2 bits (122), Expect = 1e-06
Identities = 36/132 (27%), Positives = 59/132 (44%), Gaps = 3/132 (2%)
Frame = +2
Query: 176 IVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLXWNAGEWGCXTWL-VSSERLWRP 349
+ V L + L ++ E E + L W D RL W E+ + + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 350 DVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMXTCTFKFGS 526
DVVL N A + A VS +GS+ W+ + +++ ++P D CT KF S
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRS 175
Query: 527 XMXNIDXMDFVI 562
+ +D V+
Sbjct: 176 WTYDRTEIDLVL 187
>AJ001935-1|CAA05108.1| 504|Homo sapiens CHRNB2 protein.
Length = 504
Score = 53.2 bits (122), Expect = 1e-06
Identities = 36/132 (27%), Positives = 59/132 (44%), Gaps = 3/132 (2%)
Frame = +2
Query: 176 IVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLXWNAGEWGCXTWL-VSSERLWRP 349
+ V L + L ++ E E + L W D RL W E+ + + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 350 DVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMXTCTFKFGS 526
DVVL N A + A VS +GS+ W+ + +++ ++P D CT KF S
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRS 175
Query: 527 XMXNIDXMDFVI 562
+ +D V+
Sbjct: 176 WTYDRTEIDLVL 187
>AF077186-1|AAD45422.1| 502|Homo sapiens neuronal nicotinic
acetylcholine receptor beta 2 protein.
Length = 502
Score = 53.2 bits (122), Expect = 1e-06
Identities = 36/132 (27%), Positives = 59/132 (44%), Gaps = 3/132 (2%)
Frame = +2
Query: 176 IVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLXWNAGEWGCXTWL-VSSERLWRP 349
+ V L + L ++ E E + L W D RL W E+ + + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 350 DVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMXTCTFKFGS 526
DVVL N A + A VS +GS+ W+ + +++ ++P D CT KF S
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRS 175
Query: 527 XMXNIDXMDFVI 562
+ +D V+
Sbjct: 176 WTYDRTEIDLVL 187
>DQ644022-1|ABG35128.1| 456|Homo sapiens 5-HT3 receptor subunit E
splice variant HTR3Ea protein.
Length = 456
Score = 52.4 bits (120), Expect = 2e-06
Identities = 26/100 (26%), Positives = 47/100 (47%), Gaps = 1/100 (1%)
Frame = +2
Query: 254 LQMNWIDKRLXWNAGEW-GCXTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 430
L+M W + + WN E G ++++ LW PD+ ++ L A VSN G +
Sbjct: 91 LEMVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEGRI 150
Query: 431 SWIKRLDISTPISMQLDNWPNDMXTCTFKFGSXMXNIDXM 550
+ K + + + ++ + +P D CT F S + +D M
Sbjct: 151 RYKKPMKVDSICNLDIFYFPFDQQNCTLTFSSFLYTVDSM 190
>BC131799-1|AAI31800.1| 447|Homo sapiens 5-hydroxytryptamine
(serotonin) receptor 3, family member C protein.
Length = 447
Score = 52.4 bits (120), Expect = 2e-06
Identities = 26/109 (23%), Positives = 52/109 (47%), Gaps = 1/109 (0%)
Frame = +2
Query: 254 LQMNWIDKRLXWNAGEW-GCXTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 430
+ + W + + WN E G V +E LW PD+ ++ + L A +S+ G +
Sbjct: 91 MDLVWDNPFINWNPKECVGINKLTVLAENLWLPDIFIVESMDVDQTPSGLTAYISSEGRI 150
Query: 431 SWIKRLDISTPISMQLDNWPNDMXTCTFKFGSXMXNIDXMDFVIDXXLY 577
+ K + +++ ++ + +P D CTF F S + +D M +D ++
Sbjct: 151 KYDKPMRVTSICNLDIFYFPFDQQNCTFTFSSFLYTVDSMLLGMDKEVW 199
>BC101185-1|AAI01186.1| 374|Homo sapiens HTR3E protein protein.
Length = 374
Score = 52.4 bits (120), Expect = 2e-06
Identities = 26/100 (26%), Positives = 47/100 (47%), Gaps = 1/100 (1%)
Frame = +2
Query: 254 LQMNWIDKRLXWNAGEW-GCXTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 430
L+M W + + WN E G ++++ LW PD+ ++ L A VSN G +
Sbjct: 20 LEMVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEGRI 79
Query: 431 SWIKRLDISTPISMQLDNWPNDMXTCTFKFGSXMXNIDXM 550
+ K + + + ++ + +P D CT F S + +D M
Sbjct: 80 RYKKPMKVDSICNLDIFYFPFDQQNCTLTFSSFLYTVDSM 119
>BC101183-1|AAI01184.1| 471|Homo sapiens 5-hydroxytryptamine
(serotonin) receptor 3, family member E protein.
Length = 471
Score = 52.4 bits (120), Expect = 2e-06
Identities = 26/100 (26%), Positives = 47/100 (47%), Gaps = 1/100 (1%)
Frame = +2
Query: 254 LQMNWIDKRLXWNAGEW-GCXTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 430
L+M W + + WN E G ++++ LW PD+ ++ L A VSN G +
Sbjct: 106 LEMVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEGRI 165
Query: 431 SWIKRLDISTPISMQLDNWPNDMXTCTFKFGSXMXNIDXM 550
+ K + + + ++ + +P D CT F S + +D M
Sbjct: 166 RYKKPMKVDSICNLDIFYFPFDQQNCTLTFSSFLYTVDSM 205
>BC101182-1|AAI01183.1| 471|Homo sapiens 5-hydroxytryptamine
(serotonin) receptor 3, family member E protein.
Length = 471
Score = 52.4 bits (120), Expect = 2e-06
Identities = 26/100 (26%), Positives = 47/100 (47%), Gaps = 1/100 (1%)
Frame = +2
Query: 254 LQMNWIDKRLXWNAGEW-GCXTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 430
L+M W + + WN E G ++++ LW PD+ ++ L A VSN G +
Sbjct: 106 LEMVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEGRI 165
Query: 431 SWIKRLDISTPISMQLDNWPNDMXTCTFKFGSXMXNIDXM 550
+ K + + + ++ + +P D CT F S + +D M
Sbjct: 166 RYKKPMKVDSICNLDIFYFPFDQQNCTLTFSSFLYTVDSM 205
>AY159813-1|AAO38167.2| 471|Homo sapiens 5-hydroxytryptamine
serotonin receptor 3E protein.
Length = 471
Score = 52.4 bits (120), Expect = 2e-06
Identities = 26/100 (26%), Positives = 47/100 (47%), Gaps = 1/100 (1%)
Frame = +2
Query: 254 LQMNWIDKRLXWNAGEW-GCXTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 430
L+M W + + WN E G ++++ LW PD+ ++ L A VSN G +
Sbjct: 106 LEMVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEGRI 165
Query: 431 SWIKRLDISTPISMQLDNWPNDMXTCTFKFGSXMXNIDXM 550
+ K + + + ++ + +P D CT F S + +D M
Sbjct: 166 RYKKPMKVDSICNLDIFYFPFDQQNCTLTFSSFLYTVDSM 205
>AF459285-1|AAL66182.1| 447|Homo sapiens 5-hydroxytryptamine
receptor 3 subunit C protein.
Length = 447
Score = 52.0 bits (119), Expect = 3e-06
Identities = 26/109 (23%), Positives = 51/109 (46%), Gaps = 1/109 (0%)
Frame = +2
Query: 254 LQMNWIDKRLXWNAGEW-GCXTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 430
+ + W + + WN E G V +E LW PD+ ++ + L A +S+ G +
Sbjct: 91 MDLVWDNPFINWNPKECVGINKLTVLAENLWLPDIFIVESMDVDQTPSGLTAYISSEGRI 150
Query: 431 SWIKRLDISTPISMQLDNWPNDMXTCTFKFGSXMXNIDXMDFVIDXXLY 577
+ K + +++ + + +P D CTF F S + +D M +D ++
Sbjct: 151 KYDKPMRVTSICKLDIFYFPFDQQNCTFTFSSFLYTVDSMLLGMDKEVW 199
>X01715-1|CAA25861.1| 520|Homo sapiens acetylcholine receptor gamma
chain precursor protein.
Length = 520
Score = 51.6 bits (118), Expect = 4e-06
Identities = 37/131 (28%), Positives = 60/131 (45%), Gaps = 6/131 (4%)
Frame = +2
Query: 179 VVNLTLHLRHANI---RESESTVRILADLQMNWIDKRLXWNAGEW-GCXTWLVSSERLWR 346
VVN++L L N+ E E + ++M W D RL W+ ++ G V S +WR
Sbjct: 53 VVNVSLKLTLTNLISLNEREEALTTNVWIEMQWCDYRLRWDPRDYEGLWVLRVPSTMVWR 112
Query: 347 PDVVLLNAAATTAGDYAL--RARVSNNGSVSWIKRLDISTPISMQLDNWPNDMXTCTFKF 520
PD+VL N + AL VS +G + W+ + S+ + +P D C+ F
Sbjct: 113 PDIVLEN-NVDGVFEVALYCNVLVSPDGCIYWLPPAIFRSACSISVTYFPFDWQNCSLIF 171
Query: 521 GSXMXNIDXMD 553
S + + +D
Sbjct: 172 QSQTYSTNEID 182
>AC092165-3|AAY24103.1| 520|Homo sapiens unknown protein.
Length = 520
Score = 51.6 bits (118), Expect = 4e-06
Identities = 37/131 (28%), Positives = 60/131 (45%), Gaps = 6/131 (4%)
Frame = +2
Query: 179 VVNLTLHLRHANI---RESESTVRILADLQMNWIDKRLXWNAGEW-GCXTWLVSSERLWR 346
VVN++L L N+ E E + ++M W D RL W+ ++ G V S +WR
Sbjct: 53 VVNVSLKLTLTNLISLNEREEALTTNVWIEMQWCDYRLRWDPRDYEGLWVLRVPSTMVWR 112
Query: 347 PDVVLLNAAATTAGDYAL--RARVSNNGSVSWIKRLDISTPISMQLDNWPNDMXTCTFKF 520
PD+VL N + AL VS +G + W+ + S+ + +P D C+ F
Sbjct: 113 PDIVLEN-NVDGVFEVALYCNVLVSPDGCIYWLPPAIFRSACSISVTYFPFDWQNCSLIF 171
Query: 521 GSXMXNIDXMD 553
S + + +D
Sbjct: 172 QSQTYSTNEID 182
>AY349353-1|AAQ93477.1| 456|Homo sapiens 5-HT3c1 serotonin
receptor-like protein protein.
Length = 456
Score = 50.4 bits (115), Expect = 8e-06
Identities = 26/102 (25%), Positives = 47/102 (46%), Gaps = 1/102 (0%)
Frame = +2
Query: 248 ADLQMNWIDKRLXWNAGEW-GCXTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNG 424
A L + W + + WN E G ++++ LW PD+ ++ L A VSN G
Sbjct: 89 AILDVVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEG 148
Query: 425 SVSWIKRLDISTPISMQLDNWPNDMXTCTFKFGSXMXNIDXM 550
+ + K + + + ++ + +P D CT F S + +D M
Sbjct: 149 RIRYKKPMKVDSICNLDIFYFPFDQQNCTLTFSSFLYTVDSM 190
>AY349352-1|AAQ93476.1| 441|Homo sapiens 5-HT3c1 serotonin
receptor-like protein protein.
Length = 441
Score = 50.4 bits (115), Expect = 8e-06
Identities = 26/102 (25%), Positives = 47/102 (46%), Gaps = 1/102 (0%)
Frame = +2
Query: 248 ADLQMNWIDKRLXWNAGEW-GCXTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNG 424
A L + W + + WN E G ++++ LW PD+ ++ L A VSN G
Sbjct: 74 AILDVVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEG 133
Query: 425 SVSWIKRLDISTPISMQLDNWPNDMXTCTFKFGSXMXNIDXM 550
+ + K + + + ++ + +P D CT F S + +D M
Sbjct: 134 RIRYKKPMKVDSICNLDIFYFPFDQQNCTLTFSSFLYTVDSM 175
>X55019-1|CAA38759.1| 517|Homo sapiens acetylcholine receptor delta
subunit protein.
Length = 517
Score = 50.0 bits (114), Expect = 1e-05
Identities = 29/107 (27%), Positives = 51/107 (47%), Gaps = 2/107 (1%)
Frame = +2
Query: 212 NIRESESTVRILADLQMNWIDKRLXWNAGEWGCXTWL-VSSERLWRPDVVL-LNAAATTA 385
+++E E T+ ++ W D RL WNA E+G + L + + +W P++VL N +
Sbjct: 65 SLKEVEETLTTNVWIEHGWTDNRLKWNAEEFGNISVLRLPPDMVWLPEIVLENNNDGSFQ 124
Query: 386 GDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMXTCTFKFGS 526
Y+ V + G V W+ + + + +P D C+ KF S
Sbjct: 125 ISYSCNVLVYHYGFVYWLPPAIFRSSCPISVTYFPFDWQNCSLKFSS 171
>BC093925-1|AAH93925.1| 517|Homo sapiens cholinergic receptor,
nicotinic, delta protein.
Length = 517
Score = 50.0 bits (114), Expect = 1e-05
Identities = 29/107 (27%), Positives = 51/107 (47%), Gaps = 2/107 (1%)
Frame = +2
Query: 212 NIRESESTVRILADLQMNWIDKRLXWNAGEWGCXTWL-VSSERLWRPDVVL-LNAAATTA 385
+++E E T+ ++ W D RL WNA E+G + L + + +W P++VL N +
Sbjct: 65 SLKEVEETLTTNVWIEHGWTDNRLKWNAEEFGNISVLRLPPDMVWLPEIVLENNNDGSFQ 124
Query: 386 GDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMXTCTFKFGS 526
Y+ V + G V W+ + + + +P D C+ KF S
Sbjct: 125 ISYSCNVLVYHYGFVYWLPPAIFRSSCPISVTYFPFDWQNCSLKFSS 171
>BC093923-1|AAH93923.1| 517|Homo sapiens cholinergic receptor,
nicotinic, delta protein.
Length = 517
Score = 50.0 bits (114), Expect = 1e-05
Identities = 29/107 (27%), Positives = 51/107 (47%), Gaps = 2/107 (1%)
Frame = +2
Query: 212 NIRESESTVRILADLQMNWIDKRLXWNAGEWGCXTWL-VSSERLWRPDVVL-LNAAATTA 385
+++E E T+ ++ W D RL WNA E+G + L + + +W P++VL N +
Sbjct: 65 SLKEVEETLTTNVWIEHGWTDNRLKWNAEEFGNISVLRLPPDMVWLPEIVLENNNDGSFQ 124
Query: 386 GDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMXTCTFKFGS 526
Y+ V + G V W+ + + + +P D C+ KF S
Sbjct: 125 ISYSCNVLVYHYGFVYWLPPAIFRSSCPISVTYFPFDWQNCSLKFSS 171
>AC092165-2|AAY24102.1| 517|Homo sapiens unknown protein.
Length = 517
Score = 50.0 bits (114), Expect = 1e-05
Identities = 29/107 (27%), Positives = 51/107 (47%), Gaps = 2/107 (1%)
Frame = +2
Query: 212 NIRESESTVRILADLQMNWIDKRLXWNAGEWGCXTWL-VSSERLWRPDVVL-LNAAATTA 385
+++E E T+ ++ W D RL WNA E+G + L + + +W P++VL N +
Sbjct: 65 SLKEVEETLTTNVWIEHGWTDNRLKWNAEEFGNISVLRLPPDMVWLPEIVLENNNDGSFQ 124
Query: 386 GDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMXTCTFKFGS 526
Y+ V + G V W+ + + + +P D C+ KF S
Sbjct: 125 ISYSCNVLVYHYGFVYWLPPAIFRSSCPISVTYFPFDWQNCSLKFSS 171
>BC110597-1|AAI10598.1| 411|Homo sapiens ligand-gated ion channel,
zinc activated 1 protein.
Length = 411
Score = 49.6 bits (113), Expect = 1e-05
Identities = 26/89 (29%), Positives = 41/89 (46%)
Frame = +2
Query: 254 LQMNWIDKRLXWNAGEWGCXTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVS 433
L+++W+D RL WN + E LW P + +L A D + +ARV +G V
Sbjct: 86 LRLSWLDTRLAWNTSAHPRHAITLPWESLWTPRLTILEALWVDWRDQSPQARVDQDGHVK 145
Query: 434 WIKRLDISTPISMQLDNWPNDMXTCTFKF 520
L T + +L ++P D C+ F
Sbjct: 146 LNLALTTETNCNFELLHFPRDHSNCSLSF 174
>AK122638-1|BAC85499.1| 266|Homo sapiens yte protein of 76kDa)
(LCP2). protein.
Length = 266
Score = 49.6 bits (113), Expect = 1e-05
Identities = 26/89 (29%), Positives = 41/89 (46%)
Frame = +2
Query: 254 LQMNWIDKRLXWNAGEWGCXTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVS 433
L+++W+D RL WN + E LW P + +L A D + +ARV +G V
Sbjct: 87 LRLSWLDTRLAWNTSAHPRHAITLPWESLWTPRLTILEALWVDWRDQSPQARVDQDGHVK 146
Query: 434 WIKRLDISTPISMQLDNWPNDMXTCTFKF 520
L T + +L ++P D C+ F
Sbjct: 147 LNLALTTETNCNFELLHFPRDHSNCSLSF 175
>AF512521-1|AAO20969.1| 411|Homo sapiens ligand-gated ion channel
subunit protein.
Length = 411
Score = 49.6 bits (113), Expect = 1e-05
Identities = 26/89 (29%), Positives = 41/89 (46%)
Frame = +2
Query: 254 LQMNWIDKRLXWNAGEWGCXTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVS 433
L+++W+D RL WN + E LW P + +L A D + +ARV +G V
Sbjct: 86 LRLSWLDTRLAWNTSAHPRHAITLPWESLWTPRLTILEALWVDWRDQSPQARVDQDGHVK 145
Query: 434 WIKRLDISTPISMQLDNWPNDMXTCTFKF 520
L T + +L ++P D C+ F
Sbjct: 146 LNLALTTETNCNFELLHFPRDHSNCSLSF 174
>AB223030-1|BAE19924.1| 411|Homo sapiens ligand-gated ion-channel
receptor L2 protein.
Length = 411
Score = 49.2 bits (112), Expect = 2e-05
Identities = 26/89 (29%), Positives = 41/89 (46%)
Frame = +2
Query: 254 LQMNWIDKRLXWNAGEWGCXTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVS 433
L+++W+D RL WN + E LW P + +L A D + +ARV +G V
Sbjct: 86 LRLSWLDTRLAWNTSAHPRHAITLPWESLWTPRLTILEALWVDWRDQSPQARVDQDGHVK 145
Query: 434 WIKRLDISTPISMQLDNWPNDMXTCTFKF 520
L T + +L ++P D C+ F
Sbjct: 146 LNLALATETNCNFELLHFPRDHSNCSLSF 174
>BC113575-1|AAI13576.1| 479|Homo sapiens cholinergic receptor,
nicotinic, alpha 9 protein.
Length = 479
Score = 48.4 bits (110), Expect = 3e-05
Identities = 31/130 (23%), Positives = 61/130 (46%), Gaps = 5/130 (3%)
Frame = +2
Query: 179 VVNLTLHLRHANIRESESTVRILAD---LQMNWIDKRLXWNAGEW-GCXTWLVSSERLWR 346
V+N+TL + + I++ + +IL ++ W D L W+ ++ G + + S+ +WR
Sbjct: 55 VLNVTLQITLSQIKDMDERNQILTAYLWIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWR 114
Query: 347 PDVVLLNAAATTAGD-YALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMXTCTFKFG 523
PD+VL N A + + + +G ++W + + + +P D C FG
Sbjct: 115 PDIVLYNKADDESSEPVNTNVVLRYDGLITWDAPAITKSSCVVDVTYFPFDNQQCNLTFG 174
Query: 524 SXMXNIDXMD 553
S N + +D
Sbjct: 175 SWTYNGNQVD 184
>BC113549-1|AAI13550.1| 479|Homo sapiens cholinergic receptor,
nicotinic, alpha 9 protein.
Length = 479
Score = 48.4 bits (110), Expect = 3e-05
Identities = 31/130 (23%), Positives = 61/130 (46%), Gaps = 5/130 (3%)
Frame = +2
Query: 179 VVNLTLHLRHANIRESESTVRILAD---LQMNWIDKRLXWNAGEW-GCXTWLVSSERLWR 346
V+N+TL + + I++ + +IL ++ W D L W+ ++ G + + S+ +WR
Sbjct: 55 VLNVTLQITLSQIKDMDERNQILTAYLWIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWR 114
Query: 347 PDVVLLNAAATTAGD-YALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMXTCTFKFG 523
PD+VL N A + + + +G ++W + + + +P D C FG
Sbjct: 115 PDIVLYNKADDESSEPVNTNVVLRYDGLITWDAPAITKSSCVVDVTYFPFDNQQCNLTFG 174
Query: 524 SXMXNIDXMD 553
S N + +D
Sbjct: 175 SWTYNGNQVD 184
>BC111802-1|AAI11803.1| 465|Homo sapiens CHRNG protein protein.
Length = 465
Score = 48.4 bits (110), Expect = 3e-05
Identities = 29/92 (31%), Positives = 46/92 (50%), Gaps = 5/92 (5%)
Frame = +2
Query: 179 VVNLTLHLRHANI---RESESTVRILADLQMNWIDKRLXWNAGEW-GCXTWLVSSERLWR 346
VVN++L L N+ E E + ++M W D RL W+ ++ G V S +WR
Sbjct: 50 VVNVSLKLTLTNLISLNEREEALTTNVWIEMQWCDYRLRWDPRDYEGLWVLRVPSTMVWR 109
Query: 347 PDVVLLNAAAT-TAGDYALRARVSNNGSVSWI 439
PD+VL N + T + + L+ + S+ WI
Sbjct: 110 PDIVLENKSQTYSTNEIDLQLSQEDGQSIEWI 141
>AY123244-1|AAM74523.1| 479|Homo sapiens nicotinic acetylcholine
receptor subunit alpha 9 protein.
Length = 479
Score = 48.4 bits (110), Expect = 3e-05
Identities = 31/130 (23%), Positives = 61/130 (46%), Gaps = 5/130 (3%)
Frame = +2
Query: 179 VVNLTLHLRHANIRESESTVRILAD---LQMNWIDKRLXWNAGEW-GCXTWLVSSERLWR 346
V+N+TL + + I++ + +IL ++ W D L W+ ++ G + + S+ +WR
Sbjct: 55 VLNVTLQITLSQIKDMDERNQILTAYLWIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWR 114
Query: 347 PDVVLLNAAATTAGD-YALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMXTCTFKFG 523
PD+VL N A + + + +G ++W + + + +P D C FG
Sbjct: 115 PDIVLYNKADDESSEPVNTNVVLRYDGLITWDAPAITKSSCVVDVTYFPFDNQQCNLTFG 174
Query: 524 SXMXNIDXMD 553
S N + +D
Sbjct: 175 SWTYNGNQVD 184
>AJ243342-1|CAB65091.1| 479|Homo sapiens nicotinic acetylcholine
receptor alpha 9 subunit protein.
Length = 479
Score = 48.4 bits (110), Expect = 3e-05
Identities = 31/130 (23%), Positives = 61/130 (46%), Gaps = 5/130 (3%)
Frame = +2
Query: 179 VVNLTLHLRHANIRESESTVRILAD---LQMNWIDKRLXWNAGEW-GCXTWLVSSERLWR 346
V+N+TL + + I++ + +IL ++ W D L W+ ++ G + + S+ +WR
Sbjct: 55 VLNVTLQITLSQIKDMDERNQILTAYLWIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWR 114
Query: 347 PDVVLLNAAATTAGD-YALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMXTCTFKFG 523
PD+VL N A + + + +G ++W + + + +P D C FG
Sbjct: 115 PDIVLYNKADDESSEPVNTNVVLRYDGLITWDAPAITKSSCVVDVTYFPFDNQQCNLTFG 174
Query: 524 SXMXNIDXMD 553
S N + +D
Sbjct: 175 SWTYNGNQVD 184
>AF227732-1|AAF61920.1| 470|Homo sapiens nicotinic acetylcholine
receptor alpha 9 subunit protein.
Length = 470
Score = 48.4 bits (110), Expect = 3e-05
Identities = 31/130 (23%), Positives = 61/130 (46%), Gaps = 5/130 (3%)
Frame = +2
Query: 179 VVNLTLHLRHANIRESESTVRILAD---LQMNWIDKRLXWNAGEW-GCXTWLVSSERLWR 346
V+N+TL + + I++ + +IL ++ W D L W+ ++ G + + S+ +WR
Sbjct: 49 VLNVTLQITLSQIKDMDERNQILTAYLWIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWR 108
Query: 347 PDVVLLNAAATTAGD-YALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMXTCTFKFG 523
PD+VL N A + + + +G ++W + + + +P D C FG
Sbjct: 109 PDIVLYNKADDESSEPVNTNVVLRYDGLITWDAPAITKSSCVVDVTYFPFDNQQCNLTFG 168
Query: 524 SXMXNIDXMD 553
S N + +D
Sbjct: 169 SWTYNGNQVD 178
>AC118275-1|AAY40986.1| 479|Homo sapiens unknown protein.
Length = 479
Score = 48.4 bits (110), Expect = 3e-05
Identities = 31/130 (23%), Positives = 61/130 (46%), Gaps = 5/130 (3%)
Frame = +2
Query: 179 VVNLTLHLRHANIRESESTVRILAD---LQMNWIDKRLXWNAGEW-GCXTWLVSSERLWR 346
V+N+TL + + I++ + +IL ++ W D L W+ ++ G + + S+ +WR
Sbjct: 55 VLNVTLQITLSQIKDMDERNQILTAYLWIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWR 114
Query: 347 PDVVLLNAAATTAGD-YALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMXTCTFKFG 523
PD+VL N A + + + +G ++W + + + +P D C FG
Sbjct: 115 PDIVLYNKADDESSEPVNTNVVLRYDGLITWDAPAITKSSCVVDVTYFPFDNQQCNLTFG 174
Query: 524 SXMXNIDXMD 553
S N + +D
Sbjct: 175 SWTYNGNQVD 184
>Z23141-1|CAA80672.1| 479|Homo sapiens cholinergic receptor,
nicotinic, alpha polypeptide 7 protein.
Length = 479
Score = 47.2 bits (107), Expect = 8e-05
Identities = 26/93 (27%), Positives = 45/93 (48%), Gaps = 2/93 (2%)
Frame = +2
Query: 254 LQMNWIDKRLXWNAGEW-GCXTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSNNGS 427
LQM+W D L WN E+ G T ++W+PD++L N+A + V+++G
Sbjct: 55 LQMSWTDHYLQWNVSEYPGVKTVRFPDGQIWKPDILLYNSADERFDATFHTNVLVNSSGH 114
Query: 428 VSWIKRLDISTPISMQLDNWPNDMXTCTFKFGS 526
++ + + + +P D+ C KFGS
Sbjct: 115 CQYLPPGIFKSSCYIDVRWFPFDVQHCKLKFGS 147
>Y08420-1|CAA69697.1| 502|Homo sapiens nicotinic acetylcholine
receptor alpha7 subunit precursor protein.
Length = 502
Score = 47.2 bits (107), Expect = 8e-05
Identities = 26/93 (27%), Positives = 45/93 (48%), Gaps = 2/93 (2%)
Frame = +2
Query: 254 LQMNWIDKRLXWNAGEW-GCXTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSNNGS 427
LQM+W D L WN E+ G T ++W+PD++L N+A + V+++G
Sbjct: 78 LQMSWTDHYLQWNVSEYPGVKTVRFPDGQIWKPDILLYNSADERFDATFHTNVLVNSSGH 137
Query: 428 VSWIKRLDISTPISMQLDNWPNDMXTCTFKFGS 526
++ + + + +P D+ C KFGS
Sbjct: 138 CQYLPPGIFKSSCYIDVRWFPFDVQHCKLKFGS 170
>X70297-1|CAA49778.1| 502|Homo sapiens neuronal nicotinic
acetylocholine receptor alpha-7 subunit protein.
Length = 502
Score = 47.2 bits (107), Expect = 8e-05
Identities = 26/93 (27%), Positives = 45/93 (48%), Gaps = 2/93 (2%)
Frame = +2
Query: 254 LQMNWIDKRLXWNAGEW-GCXTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSNNGS 427
LQM+W D L WN E+ G T ++W+PD++L N+A + V+++G
Sbjct: 78 LQMSWTDHYLQWNVSEYPGVKTVRFPDGQIWKPDILLYNSADERFDATFHTNVLVNSSGH 137
Query: 428 VSWIKRLDISTPISMQLDNWPNDMXTCTFKFGS 526
++ + + + +P D+ C KFGS
Sbjct: 138 CQYLPPGIFKSSCYIDVRWFPFDVQHCKLKFGS 170
>U62436-1|AAB40114.1| 502|Homo sapiens nicotinic acetylcholine
receptor alpha7 subunit precursor protein.
Length = 502
Score = 47.2 bits (107), Expect = 8e-05
Identities = 26/93 (27%), Positives = 45/93 (48%), Gaps = 2/93 (2%)
Frame = +2
Query: 254 LQMNWIDKRLXWNAGEW-GCXTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSNNGS 427
LQM+W D L WN E+ G T ++W+PD++L N+A + V+++G
Sbjct: 78 LQMSWTDHYLQWNVSEYPGVKTVRFPDGQIWKPDILLYNSADERFDATFHTNVLVNSSGH 137
Query: 428 VSWIKRLDISTPISMQLDNWPNDMXTCTFKFGS 526
++ + + + +P D+ C KFGS
Sbjct: 138 CQYLPPGIFKSSCYIDVRWFPFDVQHCKLKFGS 170
>AJ586911-1|CAE52911.1| 502|Homo sapiens nicotinic acetylcholine
alpha-7 subunit protein.
Length = 502
Score = 47.2 bits (107), Expect = 8e-05
Identities = 26/93 (27%), Positives = 45/93 (48%), Gaps = 2/93 (2%)
Frame = +2
Query: 254 LQMNWIDKRLXWNAGEW-GCXTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSNNGS 427
LQM+W D L WN E+ G T ++W+PD++L N+A + V+++G
Sbjct: 78 LQMSWTDHYLQWNVSEYPGVKTVRFPDGQIWKPDILLYNSADERFDATFHTNVLVNSSGH 137
Query: 428 VSWIKRLDISTPISMQLDNWPNDMXTCTFKFGS 526
++ + + + +P D+ C KFGS
Sbjct: 138 CQYLPPGIFKSSCYIDVRWFPFDVQHCKLKFGS 170
>U40583-1|AAA83561.1| 502|Homo sapiens alpha 7 neuronal nicotinic
acetylcholine receptor protein.
Length = 502
Score = 46.0 bits (104), Expect = 2e-04
Identities = 26/93 (27%), Positives = 44/93 (47%), Gaps = 2/93 (2%)
Frame = +2
Query: 254 LQMNWIDKRLXWNAGEW-GCXTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSNNGS 427
LQM+W D L WN E+ G T ++W+PD++L N+A + V+ +G
Sbjct: 78 LQMSWTDHYLQWNVSEYPGVKTVRFPDGQIWKPDILLYNSADERFDATFHTNVLVNPSGH 137
Query: 428 VSWIKRLDISTPISMQLDNWPNDMXTCTFKFGS 526
++ + + + +P D+ C KFGS
Sbjct: 138 CQYLPPGIFKSSCYIDVRWFPFDVQHCKLKFGS 170
>L08485-1|AAA58490.1| 462|Homo sapiens GABA-benzodiazepine receptor
alpha-5-subunit protein.
Length = 462
Score = 46.0 bits (104), Expect = 2e-04
Identities = 28/105 (26%), Positives = 49/105 (46%), Gaps = 3/105 (2%)
Frame = +2
Query: 221 ESESTVRILADLQMNWIDKRLXWNAGEWGCXTWLVSSERLWRPDVVLLNAAATTAGDYAL 400
E E T+ + + +W D+RL + + + ++W PD N + A +
Sbjct: 91 EMEYTIDVF--FRQSWKDERLRFKGPMQRLPLNNLLASKIWTPDTFFHNGKKSIAHNMTT 148
Query: 401 R---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMXTCTFKFGS 526
R+ ++G++ + RL IS MQL+++P D C KFGS
Sbjct: 149 PNKLLRLEDDGTLLYTMRLTISAECPMQLEDFPMDAHACPLKFGS 193
>BT009830-1|AAP88832.1| 462|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 5 protein.
Length = 462
Score = 46.0 bits (104), Expect = 2e-04
Identities = 28/105 (26%), Positives = 49/105 (46%), Gaps = 3/105 (2%)
Frame = +2
Query: 221 ESESTVRILADLQMNWIDKRLXWNAGEWGCXTWLVSSERLWRPDVVLLNAAATTAGDYAL 400
E E T+ + + +W D+RL + + + ++W PD N + A +
Sbjct: 91 EMEYTIDVF--FRQSWKDERLRFKGPMQRLPLNNLLASKIWTPDTFFHNGKKSIAHNMTT 148
Query: 401 R---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMXTCTFKFGS 526
R+ ++G++ + RL IS MQL+++P D C KFGS
Sbjct: 149 PNKLLRLEDDGTLLYTMRLTISAECPMQLEDFPMDAHACPLKFGS 193
>BC113422-1|AAI13423.1| 462|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 5 protein.
Length = 462
Score = 46.0 bits (104), Expect = 2e-04
Identities = 28/105 (26%), Positives = 49/105 (46%), Gaps = 3/105 (2%)
Frame = +2
Query: 221 ESESTVRILADLQMNWIDKRLXWNAGEWGCXTWLVSSERLWRPDVVLLNAAATTAGDYAL 400
E E T+ + + +W D+RL + + + ++W PD N + A +
Sbjct: 91 EMEYTIDVF--FRQSWKDERLRFKGPMQRLPLNNLLASKIWTPDTFFHNGKKSIAHNMTT 148
Query: 401 R---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMXTCTFKFGS 526
R+ ++G++ + RL IS MQL+++P D C KFGS
Sbjct: 149 PNKLLRLEDDGTLLYTMRLTISAECPMQLEDFPMDAHACPLKFGS 193
>BC111979-1|AAI11980.1| 462|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 5, precursor protein.
Length = 462
Score = 46.0 bits (104), Expect = 2e-04
Identities = 28/105 (26%), Positives = 49/105 (46%), Gaps = 3/105 (2%)
Frame = +2
Query: 221 ESESTVRILADLQMNWIDKRLXWNAGEWGCXTWLVSSERLWRPDVVLLNAAATTAGDYAL 400
E E T+ + + +W D+RL + + + ++W PD N + A +
Sbjct: 91 EMEYTIDVF--FRQSWKDERLRFKGPMQRLPLNNLLASKIWTPDTFFHNGKKSIAHNMTT 148
Query: 401 R---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMXTCTFKFGS 526
R+ ++G++ + RL IS MQL+++P D C KFGS
Sbjct: 149 PNKLLRLEDDGTLLYTMRLTISAECPMQLEDFPMDAHACPLKFGS 193
>AJ295237-1|CAC16144.1| 450|Homo sapiens neuronal nicotinic
acetylcholine receptor subunit4 protein.
Length = 450
Score = 46.0 bits (104), Expect = 2e-04
Identities = 30/120 (25%), Positives = 55/120 (45%), Gaps = 5/120 (4%)
Frame = +2
Query: 182 VNLTLHLRHANIRESESTVRILAD---LQMNWIDKRLXWNAGEWGCXTWL-VSSERLWRP 349
+N+TL + + I + + ++L ++ W D L W+ +G + + S +WRP
Sbjct: 55 LNVTLEVTLSQIIDMDERNQVLTLYLWIRQEWTDAYLRWDPNAYGGLDAIRIPSSLVWRP 114
Query: 350 DVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMXTCTFKFGS 526
D+VL N A A G + + ++G+V W + + + +P D C FGS
Sbjct: 115 DIVLYNKADAQPPGSASTNVVLRHDGAVRWDAPAITRSSCRVDVAAFPFDAQHCGLTFGS 174
>AJ278118-1|CAC20435.1| 450|Homo sapiens neuronal nicotinic
acetylcholine alpha10 subunit protein.
Length = 450
Score = 46.0 bits (104), Expect = 2e-04
Identities = 30/120 (25%), Positives = 55/120 (45%), Gaps = 5/120 (4%)
Frame = +2
Query: 182 VNLTLHLRHANIRESESTVRILAD---LQMNWIDKRLXWNAGEWGCXTWL-VSSERLWRP 349
+N+TL + + I + + ++L ++ W D L W+ +G + + S +WRP
Sbjct: 55 LNVTLEVTLSQIIDMDERNQVLTLYLWIRQEWTDAYLRWDPNAYGGLDAIRIPSSLVWRP 114
Query: 350 DVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMXTCTFKFGS 526
D+VL N A A G + + ++G+V W + + + +P D C FGS
Sbjct: 115 DIVLYNKADAQPPGSASTNVVLRHDGAVRWDAPAITRSSCRVDVAAFPFDAQHCGLTFGS 174
>AF385585-1|AAK68111.1| 502|Homo sapiens nicotinic cholinergic
receptor alpha 7 protein.
Length = 502
Score = 46.0 bits (104), Expect = 2e-04
Identities = 26/93 (27%), Positives = 44/93 (47%), Gaps = 2/93 (2%)
Frame = +2
Query: 254 LQMNWIDKRLXWNAGEW-GCXTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSNNGS 427
LQM+W D L WN E+ G T ++W+PD++L N+A + V+ +G
Sbjct: 78 LQMSWTDHYLQWNVSEYPGVKTVRFPDGQIWKPDILLYNSADERFDATFHTNVLVNPSGH 137
Query: 428 VSWIKRLDISTPISMQLDNWPNDMXTCTFKFGS 526
++ + + + +P D+ C KFGS
Sbjct: 138 CQYLPPGIFKSSCYIDVRWFPFDVQHCKLKFGS 170
>AF327367-1|AAK14333.1| 450|Homo sapiens nicotinic acetylcholine
receptor subunit alpha 10 protein.
Length = 450
Score = 46.0 bits (104), Expect = 2e-04
Identities = 30/120 (25%), Positives = 55/120 (45%), Gaps = 5/120 (4%)
Frame = +2
Query: 182 VNLTLHLRHANIRESESTVRILAD---LQMNWIDKRLXWNAGEWGCXTWL-VSSERLWRP 349
+N+TL + + I + + ++L ++ W D L W+ +G + + S +WRP
Sbjct: 55 LNVTLEVTLSQIIDMDERNQVLTLYLWIRQEWTDAYLRWDPNAYGGLDAIRIPSSLVWRP 114
Query: 350 DVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMXTCTFKFGS 526
D+VL N A A G + + ++G+V W + + + +P D C FGS
Sbjct: 115 DIVLYNKADAQPPGSASTNVVLRHDGAVRWDAPAITRSSCRVDVAAFPFDAQHCGLTFGS 174
>AF199235-1|AAG00795.2| 450|Homo sapiens nicotinic acetylcholine
receptor subunit alpha 10 protein.
Length = 450
Score = 46.0 bits (104), Expect = 2e-04
Identities = 30/120 (25%), Positives = 55/120 (45%), Gaps = 5/120 (4%)
Frame = +2
Query: 182 VNLTLHLRHANIRESESTVRILAD---LQMNWIDKRLXWNAGEWGCXTWL-VSSERLWRP 349
+N+TL + + I + + ++L ++ W D L W+ +G + + S +WRP
Sbjct: 55 LNVTLEVTLSQIIDMDERNQVLTLYLWIRQEWTDAYLRWDPNAYGGLDAIRIPSSLVWRP 114
Query: 350 DVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMXTCTFKFGS 526
D+VL N A A G + + ++G+V W + + + +P D C FGS
Sbjct: 115 DIVLYNKADAQPPGSASTNVVLRHDGAVRWDAPAITRSSCRVDVAAFPFDAQHCGLTFGS 174
>U77731-2|AAB38273.1| 360|Homo sapiens glycine receptor alpha 2B
subunit protein.
Length = 360
Score = 45.2 bits (102), Expect = 3e-04
Identities = 34/132 (25%), Positives = 57/132 (43%), Gaps = 7/132 (5%)
Frame = +2
Query: 182 VNLTLHL---RHANIRESESTVRILADLQMNWIDKRLXWNAGEWGCXTWLVSS-ERLWRP 349
VN+T ++ +I E+ R+ L+ W D RL ++ S + +W+P
Sbjct: 71 VNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDSRLAYSEYPDDSLDLDPSMLDSIWKP 130
Query: 350 DVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMXTCTFKF 520
D+ N D R+S NG V + RL ++ M L N+P D+ TCT +
Sbjct: 131 DLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNFPMDVQTCTMQL 190
Query: 521 GSXMXNIDXMDF 556
S ++ + F
Sbjct: 191 ESFGYTMNDLIF 202
>CR450343-1|CAG29339.1| 452|Homo sapiens GLRA2 protein.
Length = 452
Score = 45.2 bits (102), Expect = 3e-04
Identities = 34/132 (25%), Positives = 57/132 (43%), Gaps = 7/132 (5%)
Frame = +2
Query: 182 VNLTLHL---RHANIRESESTVRILADLQMNWIDKRLXWNAGEWGCXTWLVSS-ERLWRP 349
VN+T ++ +I E+ R+ L+ W D RL ++ S + +W+P
Sbjct: 71 VNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDSRLAYSEYPDDSLDLDPSMLDSIWKP 130
Query: 350 DVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMXTCTFKF 520
D+ N D R+S NG V + RL ++ M L N+P D+ TCT +
Sbjct: 131 DLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNFPMDVQTCTMQL 190
Query: 521 GSXMXNIDXMDF 556
S ++ + F
Sbjct: 191 ESFGYTMNDLIF 202
>AY437084-1|AAR87843.1| 452|Homo sapiens glycine receptor alpha2
subunit B protein.
Length = 452
Score = 45.2 bits (102), Expect = 3e-04
Identities = 34/132 (25%), Positives = 57/132 (43%), Gaps = 7/132 (5%)
Frame = +2
Query: 182 VNLTLHL---RHANIRESESTVRILADLQMNWIDKRLXWNAGEWGCXTWLVSS-ERLWRP 349
VN+T ++ +I E+ R+ L+ W D RL ++ S + +W+P
Sbjct: 71 VNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDSRLAYSEYPDDSLDLDPSMLDSIWKP 130
Query: 350 DVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMXTCTFKF 520
D+ N D R+S NG V + RL ++ M L N+P D+ TCT +
Sbjct: 131 DLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNFPMDVQTCTMQL 190
Query: 521 GSXMXNIDXMDF 556
S ++ + F
Sbjct: 191 ESFGYTMNDLIF 202
>X52008-1|CAA36257.1| 452|Homo sapiens inhibitory glycine receptor
protein.
Length = 452
Score = 44.8 bits (101), Expect = 4e-04
Identities = 33/132 (25%), Positives = 57/132 (43%), Gaps = 7/132 (5%)
Frame = +2
Query: 182 VNLTLHL---RHANIRESESTVRILADLQMNWIDKRLXWNAGEWGCXTWLVSS-ERLWRP 349
VN+T ++ ++ E+ R+ L+ W D RL ++ S + +W+P
Sbjct: 71 VNVTCNIFINSFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPDDSLDLDPSMLDSIWKP 130
Query: 350 DVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMXTCTFKF 520
D+ N D R+S NG V + RL ++ M L N+P D+ TCT +
Sbjct: 131 DLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNFPMDVQTCTMQL 190
Query: 521 GSXMXNIDXMDF 556
S ++ + F
Sbjct: 191 ESFGYTMNDLIF 202
>U77731-1|AAB38272.1| 360|Homo sapiens glycine receptor alpha 2
subunit protein.
Length = 360
Score = 44.8 bits (101), Expect = 4e-04
Identities = 33/132 (25%), Positives = 57/132 (43%), Gaps = 7/132 (5%)
Frame = +2
Query: 182 VNLTLHL---RHANIRESESTVRILADLQMNWIDKRLXWNAGEWGCXTWLVSS-ERLWRP 349
VN+T ++ ++ E+ R+ L+ W D RL ++ S + +W+P
Sbjct: 71 VNVTCNIFINSFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPDDSLDLDPSMLDSIWKP 130
Query: 350 DVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMXTCTFKF 520
D+ N D R+S NG V + RL ++ M L N+P D+ TCT +
Sbjct: 131 DLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNFPMDVQTCTMQL 190
Query: 521 GSXMXNIDXMDF 556
S ++ + F
Sbjct: 191 ESFGYTMNDLIF 202
>BC032864-1|AAH32864.1| 452|Homo sapiens glycine receptor, alpha 2
protein.
Length = 452
Score = 44.8 bits (101), Expect = 4e-04
Identities = 33/132 (25%), Positives = 57/132 (43%), Gaps = 7/132 (5%)
Frame = +2
Query: 182 VNLTLHL---RHANIRESESTVRILADLQMNWIDKRLXWNAGEWGCXTWLVSS-ERLWRP 349
VN+T ++ ++ E+ R+ L+ W D RL ++ S + +W+P
Sbjct: 71 VNVTCNIFINSFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPDDSLDLDPSMLDSIWKP 130
Query: 350 DVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMXTCTFKF 520
D+ N D R+S NG V + RL ++ M L N+P D+ TCT +
Sbjct: 131 DLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNFPMDVQTCTMQL 190
Query: 521 GSXMXNIDXMDF 556
S ++ + F
Sbjct: 191 ESFGYTMNDLIF 202
>AY437083-1|AAR87842.1| 452|Homo sapiens glycine receptor alpha2
subunit A protein.
Length = 452
Score = 44.8 bits (101), Expect = 4e-04
Identities = 33/132 (25%), Positives = 57/132 (43%), Gaps = 7/132 (5%)
Frame = +2
Query: 182 VNLTLHL---RHANIRESESTVRILADLQMNWIDKRLXWNAGEWGCXTWLVSS-ERLWRP 349
VN+T ++ ++ E+ R+ L+ W D RL ++ S + +W+P
Sbjct: 71 VNVTCNIFINSFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPDDSLDLDPSMLDSIWKP 130
Query: 350 DVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMXTCTFKF 520
D+ N D R+S NG V + RL ++ M L N+P D+ TCT +
Sbjct: 131 DLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNFPMDVQTCTMQL 190
Query: 521 GSXMXNIDXMDF 556
S ++ + F
Sbjct: 191 ESFGYTMNDLIF 202
>AF053495-1|AAC35290.1| 452|Homo sapiens glycine receptor alpha 2
subunit protein.
Length = 452
Score = 44.8 bits (101), Expect = 4e-04
Identities = 33/132 (25%), Positives = 57/132 (43%), Gaps = 7/132 (5%)
Frame = +2
Query: 182 VNLTLHL---RHANIRESESTVRILADLQMNWIDKRLXWNAGEWGCXTWLVSS-ERLWRP 349
VN+T ++ ++ E+ R+ L+ W D RL ++ S + +W+P
Sbjct: 71 VNVTCNIFINSFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPDDSLDLDPSMLDSIWKP 130
Query: 350 DVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMXTCTFKF 520
D+ N D R+S NG V + RL ++ M L N+P D+ TCT +
Sbjct: 131 DLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNFPMDVQTCTMQL 190
Query: 521 GSXMXNIDXMDF 556
S ++ + F
Sbjct: 191 ESFGYTMNDLIF 202
>U30461-1|AAB52519.1| 554|Homo sapiens GABAA receptor subunit
alpha4 protein.
Length = 554
Score = 44.4 bits (100), Expect = 6e-04
Identities = 29/105 (27%), Positives = 47/105 (44%), Gaps = 3/105 (2%)
Frame = +2
Query: 221 ESESTVRILADLQMNWIDKRLXWNAGEWGCXTWLVSSERLWRPDVVLLNAAATTAGDYAL 400
E E T+ + + WIDKRL ++ + ++W PD N + + +
Sbjct: 90 EMEYTMDVF--FRQTWIDKRLKYDGPIEILRLNNMMVTKVWTPDTFFRNGKKSVSHNMTA 147
Query: 401 RA---RVSNNGSVSWIKRLDISTPISMQLDNWPNDMXTCTFKFGS 526
R+ NG++ + RL IS M+L ++P D C KFGS
Sbjct: 148 PNKLFRIMRNGTILYTMRLTISAECPMRLVDFPMDGHACPLKFGS 192
>BC035055-1|AAH35055.1| 554|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 4 protein.
Length = 554
Score = 44.4 bits (100), Expect = 6e-04
Identities = 29/105 (27%), Positives = 47/105 (44%), Gaps = 3/105 (2%)
Frame = +2
Query: 221 ESESTVRILADLQMNWIDKRLXWNAGEWGCXTWLVSSERLWRPDVVLLNAAATTAGDYAL 400
E E T+ + + WIDKRL ++ + ++W PD N + + +
Sbjct: 90 EMEYTMDVF--FRQTWIDKRLKYDGPIEILRLNNMMVTKVWTPDTFFRNGKKSVSHNMTA 147
Query: 401 RA---RVSNNGSVSWIKRLDISTPISMQLDNWPNDMXTCTFKFGS 526
R+ NG++ + RL IS M+L ++P D C KFGS
Sbjct: 148 PNKLFRIMRNGTILYTMRLTISAECPMRLVDFPMDGHACPLKFGS 192
>S81944-1|AAB36480.1| 453|Homo sapiens gamma-aminobutyric acid type
A receptor alpha 6 subunit protein.
Length = 453
Score = 43.2 bits (97), Expect = 0.001
Identities = 28/105 (26%), Positives = 45/105 (42%), Gaps = 3/105 (2%)
Frame = +2
Query: 221 ESESTVRILADLQMNWIDKRLXWNAGEWGCXTWLVSSERLWRPDVVLLNAAATTAGDYAL 400
E E T+ + + W D+RL + + ++W PD N + A +
Sbjct: 74 EMEYTMDVF--FRQTWTDERLKFGGPTEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTT 131
Query: 401 RA---RVSNNGSVSWIKRLDISTPISMQLDNWPNDMXTCTFKFGS 526
R+ NG++ + RL I+ M+L N+P D C KFGS
Sbjct: 132 PNKLFRIMQNGTILYTMRLTINADCPMRLVNFPMDGHACPLKFGS 176
>BC099641-1|AAH99641.1| 453|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 6 protein.
Length = 453
Score = 43.2 bits (97), Expect = 0.001
Identities = 28/105 (26%), Positives = 45/105 (42%), Gaps = 3/105 (2%)
Frame = +2
Query: 221 ESESTVRILADLQMNWIDKRLXWNAGEWGCXTWLVSSERLWRPDVVLLNAAATTAGDYAL 400
E E T+ + + W D+RL + + ++W PD N + A +
Sbjct: 74 EMEYTMDVF--FRQTWTDERLKFGGPTEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTT 131
Query: 401 RA---RVSNNGSVSWIKRLDISTPISMQLDNWPNDMXTCTFKFGS 526
R+ NG++ + RL I+ M+L N+P D C KFGS
Sbjct: 132 PNKLFRIMQNGTILYTMRLTINADCPMRLVNFPMDGHACPLKFGS 176
>BC099640-1|AAH99640.1| 453|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 6 protein.
Length = 453
Score = 43.2 bits (97), Expect = 0.001
Identities = 28/105 (26%), Positives = 45/105 (42%), Gaps = 3/105 (2%)
Frame = +2
Query: 221 ESESTVRILADLQMNWIDKRLXWNAGEWGCXTWLVSSERLWRPDVVLLNAAATTAGDYAL 400
E E T+ + + W D+RL + + ++W PD N + A +
Sbjct: 74 EMEYTMDVF--FRQTWTDERLKFGGPTEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTT 131
Query: 401 RA---RVSNNGSVSWIKRLDISTPISMQLDNWPNDMXTCTFKFGS 526
R+ NG++ + RL I+ M+L N+P D C KFGS
Sbjct: 132 PNKLFRIMQNGTILYTMRLTINADCPMRLVNFPMDGHACPLKFGS 176
>BC096242-1|AAH96242.1| 453|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 6 protein.
Length = 453
Score = 43.2 bits (97), Expect = 0.001
Identities = 28/105 (26%), Positives = 45/105 (42%), Gaps = 3/105 (2%)
Frame = +2
Query: 221 ESESTVRILADLQMNWIDKRLXWNAGEWGCXTWLVSSERLWRPDVVLLNAAATTAGDYAL 400
E E T+ + + W D+RL + + ++W PD N + A +
Sbjct: 74 EMEYTMDVF--FRQTWTDERLKFGGPTEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTT 131
Query: 401 RA---RVSNNGSVSWIKRLDISTPISMQLDNWPNDMXTCTFKFGS 526
R+ NG++ + RL I+ M+L N+P D C KFGS
Sbjct: 132 PNKLFRIMQNGTILYTMRLTINADCPMRLVNFPMDGHACPLKFGS 176
>BC096241-1|AAH96241.1| 453|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 6 protein.
Length = 453
Score = 43.2 bits (97), Expect = 0.001
Identities = 28/105 (26%), Positives = 45/105 (42%), Gaps = 3/105 (2%)
Frame = +2
Query: 221 ESESTVRILADLQMNWIDKRLXWNAGEWGCXTWLVSSERLWRPDVVLLNAAATTAGDYAL 400
E E T+ + + W D+RL + + ++W PD N + A +
Sbjct: 74 EMEYTMDVF--FRQTWTDERLKFGGPTEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTT 131
Query: 401 RA---RVSNNGSVSWIKRLDISTPISMQLDNWPNDMXTCTFKFGS 526
R+ NG++ + RL I+ M+L N+P D C KFGS
Sbjct: 132 PNKLFRIMQNGTILYTMRLTINADCPMRLVNFPMDGHACPLKFGS 176
>BC028629-1|AAH28629.1| 492|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 3 protein.
Length = 492
Score = 42.3 bits (95), Expect = 0.002
Identities = 24/93 (25%), Positives = 43/93 (46%), Gaps = 3/93 (3%)
Frame = +2
Query: 257 QMNWIDKRLXWNAGEWGCXTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGS 427
+ W D+RL ++ + + ++W PD N + A + R+ +NG+
Sbjct: 119 RQTWHDERLKFDGPMKILPLNNLLASKIWTPDTFFHNGKKSVAHNMTTPNKLLRLVDNGT 178
Query: 428 VSWIKRLDISTPISMQLDNWPNDMXTCTFKFGS 526
+ + RL I M L+++P D+ C KFGS
Sbjct: 179 LPYTMRLTIHAECPMHLEDFPMDVHACPLKFGS 211
>S62908-1|AAB27279.1| 492|Homo sapiens gamma-aminobutyric acidA
receptor alpha 3 subunit protein.
Length = 492
Score = 41.9 bits (94), Expect = 0.003
Identities = 24/93 (25%), Positives = 43/93 (46%), Gaps = 3/93 (3%)
Frame = +2
Query: 257 QMNWIDKRLXWNAGEWGCXTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGS 427
+ W D+RL ++ + + ++W PD N + A + R+ +NG+
Sbjct: 119 RQTWHDERLKFDGPMKILPLNNLLASKIWTPDTFFHNGKKSVAHNMTTPNKLLRLVDNGT 178
Query: 428 VSWIKRLDISTPISMQLDNWPNDMXTCTFKFGS 526
+ + RL I M L+++P D+ C KFGS
Sbjct: 179 LLYTMRLTIHAECPMHLEDFPMDVHACPLKFGS 211
>BC096083-1|AAH96083.1| 198|Homo sapiens CHRNB4 protein protein.
Length = 198
Score = 41.9 bits (94), Expect = 0.003
Identities = 22/75 (29%), Positives = 36/75 (48%), Gaps = 2/75 (2%)
Frame = +2
Query: 176 IVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLXWNAGEW-GCXTWLVSSERLWRP 349
I + L L L ++ E E + L+ W D RL WN+ + G + ++R+W P
Sbjct: 54 ISIKLQLSLAQLISVNEREQIMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLP 113
Query: 350 DVVLLNAAATTAGDY 394
D+VL N + T +
Sbjct: 114 DIVLYNKSLRTGSTW 128
>BC096081-1|AAH96081.1| 198|Homo sapiens CHRNB4 protein protein.
Length = 198
Score = 41.9 bits (94), Expect = 0.003
Identities = 22/75 (29%), Positives = 36/75 (48%), Gaps = 2/75 (2%)
Frame = +2
Query: 176 IVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLXWNAGEW-GCXTWLVSSERLWRP 349
I + L L L ++ E E + L+ W D RL WN+ + G + ++R+W P
Sbjct: 54 ISIKLQLSLAQLISVNEREQIMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLP 113
Query: 350 DVVLLNAAATTAGDY 394
D+VL N + T +
Sbjct: 114 DIVLYNKSLRTGSTW 128
>AF166361-1|AAG12455.1| 492|Homo sapiens GABA receptor subunit
alpha 3 protein.
Length = 492
Score = 41.9 bits (94), Expect = 0.003
Identities = 24/93 (25%), Positives = 43/93 (46%), Gaps = 3/93 (3%)
Frame = +2
Query: 257 QMNWIDKRLXWNAGEWGCXTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGS 427
+ W D+RL ++ + + ++W PD N + A + R+ +NG+
Sbjct: 119 RQTWHDERLKFDGPMKILPLNNLLASKIWTPDTFFHNGKKSVAHNMTTPNKLLRLVDNGT 178
Query: 428 VSWIKRLDISTPISMQLDNWPNDMXTCTFKFGS 526
+ + RL I M L+++P D+ C KFGS
Sbjct: 179 LLYTMRLTIHAECPMHLEDFPMDVHACPLKFGS 211
>X52009-1|CAA36258.1| 449|Homo sapiens inhibitory glycine receptor
protein.
Length = 449
Score = 41.1 bits (92), Expect = 0.005
Identities = 29/119 (24%), Positives = 51/119 (42%), Gaps = 4/119 (3%)
Frame = +2
Query: 212 NIRESESTVRILADLQMNWIDKRLXWNAGEWGCXTWLVSS-ERLWRPDVVLLNAAATTAG 388
+I E+ R+ L+ W D RL +N S + +W+PD+ N
Sbjct: 78 SIAETTMDYRVNIFLRQQWNDPRLAYNEYPDDSLDLDPSMLDSIWKPDLFFANEKGAHFH 137
Query: 389 DYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMXTCTFKFGSXMXNIDXMDF 556
+ R+S NG+V + R+ ++ M L N+P D+ TC + S ++ + F
Sbjct: 138 EITTDNKLLRISRNGNVLYSIRITLTLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIF 196
>BC114947-1|AAI14948.1| 457|Homo sapiens GLRA1 protein protein.
Length = 457
Score = 41.1 bits (92), Expect = 0.005
Identities = 29/119 (24%), Positives = 51/119 (42%), Gaps = 4/119 (3%)
Frame = +2
Query: 212 NIRESESTVRILADLQMNWIDKRLXWNAGEWGCXTWLVSS-ERLWRPDVVLLNAAATTAG 388
+I E+ R+ L+ W D RL +N S + +W+PD+ N
Sbjct: 78 SIAETTMDYRVNIFLRQQWNDPRLAYNEYPDDSLDLDPSMLDSIWKPDLFFANEKGAHFH 137
Query: 389 DYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMXTCTFKFGSXMXNIDXMDF 556
+ R+S NG+V + R+ ++ M L N+P D+ TC + S ++ + F
Sbjct: 138 EITTDNKLLRISRNGNVLYSIRITLTLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIF 196
>BC074980-1|AAH74980.1| 449|Homo sapiens glycine receptor, alpha 1
(startle disease/hyperekplexia) protein.
Length = 449
Score = 41.1 bits (92), Expect = 0.005
Identities = 29/119 (24%), Positives = 51/119 (42%), Gaps = 4/119 (3%)
Frame = +2
Query: 212 NIRESESTVRILADLQMNWIDKRLXWNAGEWGCXTWLVSS-ERLWRPDVVLLNAAATTAG 388
+I E+ R+ L+ W D RL +N S + +W+PD+ N
Sbjct: 78 SIAETTMDYRVNIFLRQQWNDPRLAYNEYPDDSLDLDPSMLDSIWKPDLFFANEKGAHFH 137
Query: 389 DYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMXTCTFKFGSXMXNIDXMDF 556
+ R+S NG+V + R+ ++ M L N+P D+ TC + S ++ + F
Sbjct: 138 EITTDNKLLRISRNGNVLYSIRITLTLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIF 196
>U95367-1|AAC51357.1| 440|Homo sapiens GABA-A receptor pi subunit
protein.
Length = 440
Score = 39.5 bits (88), Expect = 0.016
Identities = 31/132 (23%), Positives = 61/132 (46%), Gaps = 5/132 (3%)
Frame = +2
Query: 176 IVVNLTLHLRH-ANIRESESTVRILADLQMNWIDKRLXWNAGE-WGCXTWLVSSERLWRP 349
+ + LTL + ++I ES L+ W+D+RL + + + LV E LW P
Sbjct: 61 VQIALTLDIASISSISESNMDYTATIYLRQRWMDQRLVFEGNKSFTLDARLV--EFLWVP 118
Query: 350 DVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMXTCTFKF 520
D ++ + + + + R+ +NG+V + R+ + +M L +P D TC +
Sbjct: 119 DTYIVESKKSFLHEVTVGNRLIRLFSNGTVLYALRITTTVACNMDLSKYPMDTQTCKLQL 178
Query: 521 GSXMXNIDXMDF 556
S + + ++F
Sbjct: 179 ESWGYDGNDVEF 190
>BC109106-1|AAI09107.1| 440|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, pi protein.
Length = 440
Score = 39.5 bits (88), Expect = 0.016
Identities = 31/132 (23%), Positives = 61/132 (46%), Gaps = 5/132 (3%)
Frame = +2
Query: 176 IVVNLTLHLRH-ANIRESESTVRILADLQMNWIDKRLXWNAGE-WGCXTWLVSSERLWRP 349
+ + LTL + ++I ES L+ W+D+RL + + + LV E LW P
Sbjct: 61 VQIALTLDIASISSISESNMDYTATIYLRQRWMDQRLVFEGNKSFTLDARLV--EFLWVP 118
Query: 350 DVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMXTCTFKF 520
D ++ + + + + R+ +NG+V + R+ + +M L +P D TC +
Sbjct: 119 DTYIVESKKSFLHEVTVGNRLIRLFSNGTVLYALRITTTVACNMDLSKYPMDTQTCKLQL 178
Query: 521 GSXMXNIDXMDF 556
S + + ++F
Sbjct: 179 ESWGYDGNDVEF 190
>BC109105-1|AAI09106.1| 440|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, pi protein.
Length = 440
Score = 39.5 bits (88), Expect = 0.016
Identities = 31/132 (23%), Positives = 61/132 (46%), Gaps = 5/132 (3%)
Frame = +2
Query: 176 IVVNLTLHLRH-ANIRESESTVRILADLQMNWIDKRLXWNAGE-WGCXTWLVSSERLWRP 349
+ + LTL + ++I ES L+ W+D+RL + + + LV E LW P
Sbjct: 61 VQIALTLDIASISSISESNMDYTATIYLRQRWMDQRLVFEGNKSFTLDARLV--EFLWVP 118
Query: 350 DVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMXTCTFKF 520
D ++ + + + + R+ +NG+V + R+ + +M L +P D TC +
Sbjct: 119 DTYIVESKKSFLHEVTVGNRLIRLFSNGTVLYALRITTTVACNMDLSKYPMDTQTCKLQL 178
Query: 521 GSXMXNIDXMDF 556
S + + ++F
Sbjct: 179 ESWGYDGNDVEF 190
>BC074865-1|AAH74865.1| 440|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, pi protein.
Length = 440
Score = 39.5 bits (88), Expect = 0.016
Identities = 31/132 (23%), Positives = 61/132 (46%), Gaps = 5/132 (3%)
Frame = +2
Query: 176 IVVNLTLHLRH-ANIRESESTVRILADLQMNWIDKRLXWNAGE-WGCXTWLVSSERLWRP 349
+ + LTL + ++I ES L+ W+D+RL + + + LV E LW P
Sbjct: 61 VQIALTLDIASISSISESNMDYTATIYLRQRWMDQRLVFEGNKSFTLDARLV--EFLWVP 118
Query: 350 DVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMXTCTFKF 520
D ++ + + + + R+ +NG+V + R+ + +M L +P D TC +
Sbjct: 119 DTYIVESKKSFLHEVTVGNRLIRLFSNGTVLYALRITTTVACNMDLSKYPMDTQTCKLQL 178
Query: 521 GSXMXNIDXMDF 556
S + + ++F
Sbjct: 179 ESWGYDGNDVEF 190
>BC074810-1|AAH74810.1| 440|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, pi protein.
Length = 440
Score = 39.5 bits (88), Expect = 0.016
Identities = 31/132 (23%), Positives = 61/132 (46%), Gaps = 5/132 (3%)
Frame = +2
Query: 176 IVVNLTLHLRH-ANIRESESTVRILADLQMNWIDKRLXWNAGE-WGCXTWLVSSERLWRP 349
+ + LTL + ++I ES L+ W+D+RL + + + LV E LW P
Sbjct: 61 VQIALTLDIASISSISESNMDYTATIYLRQRWMDQRLVFEGNKSFTLDARLV--EFLWVP 118
Query: 350 DVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMXTCTFKF 520
D ++ + + + + R+ +NG+V + R+ + +M L +P D TC +
Sbjct: 119 DTYIVESKKSFLHEVTVGNRLIRLFSNGTVLYALRITTTVACNMDLSKYPMDTQTCKLQL 178
Query: 521 GSXMXNIDXMDF 556
S + + ++F
Sbjct: 179 ESWGYDGNDVEF 190
>AF009702-1|AAC24194.1| 440|Homo sapiens GABA-A receptor pi subunit
protein.
Length = 440
Score = 39.5 bits (88), Expect = 0.016
Identities = 31/132 (23%), Positives = 61/132 (46%), Gaps = 5/132 (3%)
Frame = +2
Query: 176 IVVNLTLHLRH-ANIRESESTVRILADLQMNWIDKRLXWNAGE-WGCXTWLVSSERLWRP 349
+ + LTL + ++I ES L+ W+D+RL + + + LV E LW P
Sbjct: 61 VQIALTLDIASISSISESNMDYTATIYLRQRWMDQRLVFEGNKSFTLDARLV--EFLWVP 118
Query: 350 DVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMXTCTFKF 520
D ++ + + + + R+ +NG+V + R+ + +M L +P D TC +
Sbjct: 119 DTYIVESKKSFLHEVTVGNRLIRLFSNGTVLYALRITTTVACNMDLSKYPMDTQTCKLQL 178
Query: 521 GSXMXNIDXMDF 556
S + + ++F
Sbjct: 179 ESWGYDGNDVEF 190
>U93917-1|AAC39917.1| 449|Homo sapiens glycine receptor alpha 3
subunit protein.
Length = 449
Score = 38.7 bits (86), Expect = 0.027
Identities = 31/132 (23%), Positives = 56/132 (42%), Gaps = 7/132 (5%)
Frame = +2
Query: 182 VNLTLHL---RHANIRESESTVRILADLQMNWIDKRLXWNAGEWGCXTWLVSS-ERLWRP 349
VN+T ++ +I E+ R+ L+ W D RL ++ S + +W+P
Sbjct: 70 VNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPDDSLDLDPSMLDSIWKP 129
Query: 350 DVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMXTCTFKF 520
D+ N + R+ NG+V + RL ++ M L N+P D+ TC +
Sbjct: 130 DLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFPMDVQTCIMQL 189
Query: 521 GSXMXNIDXMDF 556
S ++ + F
Sbjct: 190 ESFGYTMNDLIF 201
>BC114967-1|AAI14968.1| 366|Homo sapiens GLRA1 protein protein.
Length = 366
Score = 38.7 bits (86), Expect = 0.027
Identities = 27/110 (24%), Positives = 47/110 (42%), Gaps = 4/110 (3%)
Frame = +2
Query: 239 RILADLQMNWIDKRLXWNAGEWGCXTWLVSS-ERLWRPDVVLLNAAATTAGDYALR---A 406
R+ L+ W D RL +N S + +W+PD+ N +
Sbjct: 4 RVNIFLRQQWNDPRLAYNEYPDDSLDLDPSMLDSIWKPDLFFANEKGAHFHEITTDNKLL 63
Query: 407 RVSNNGSVSWIKRLDISTPISMQLDNWPNDMXTCTFKFGSXMXNIDXMDF 556
R+S NG+V + R+ ++ M L N+P D+ TC + S ++ + F
Sbjct: 64 RISRNGNVLYSIRITLTLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIF 113
>BC036086-1|AAH36086.1| 464|Homo sapiens glycine receptor, alpha 3
protein.
Length = 464
Score = 38.7 bits (86), Expect = 0.027
Identities = 31/132 (23%), Positives = 56/132 (42%), Gaps = 7/132 (5%)
Frame = +2
Query: 182 VNLTLHL---RHANIRESESTVRILADLQMNWIDKRLXWNAGEWGCXTWLVSS-ERLWRP 349
VN+T ++ +I E+ R+ L+ W D RL ++ S + +W+P
Sbjct: 70 VNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPDDSLDLDPSMLDSIWKP 129
Query: 350 DVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMXTCTFKF 520
D+ N + R+ NG+V + RL ++ M L N+P D+ TC +
Sbjct: 130 DLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFPMDVQTCIMQL 189
Query: 521 GSXMXNIDXMDF 556
S ++ + F
Sbjct: 190 ESFGYTMNDLIF 201
>AF017724-1|AAC39919.1| 465|Homo sapiens glycine receptor alpha 3
subunit protein.
Length = 465
Score = 38.7 bits (86), Expect = 0.027
Identities = 31/132 (23%), Positives = 56/132 (42%), Gaps = 7/132 (5%)
Frame = +2
Query: 182 VNLTLHL---RHANIRESESTVRILADLQMNWIDKRLXWNAGEWGCXTWLVSS-ERLWRP 349
VN+T ++ +I E+ R+ L+ W D RL ++ S + +W+P
Sbjct: 70 VNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPDDSLDLDPSMLDSIWKP 129
Query: 350 DVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMXTCTFKF 520
D+ N + R+ NG+V + RL ++ M L N+P D+ TC +
Sbjct: 130 DLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFPMDVQTCIMQL 189
Query: 521 GSXMXNIDXMDF 556
S ++ + F
Sbjct: 190 ESFGYTMNDLIF 201
>Z93848-1|CAI41994.1| 376|Homo sapiens glycine receptor, alpha 4
protein.
Length = 376
Score = 37.9 bits (84), Expect = 0.048
Identities = 30/122 (24%), Positives = 52/122 (42%), Gaps = 7/122 (5%)
Frame = +2
Query: 182 VNLTLHL---RHANIRESESTVRILADLQMNWIDKRLXWNAGEWGCXTWLVSS-ERLWRP 349
VN+T ++ ++I ++ R+ L+ W D RL + S + +W+P
Sbjct: 30 VNVTCNIFINSFSSITKTTMDYRVNVFLRQQWNDPRLSYREYPDDSLDLDPSMLDSIWKP 89
Query: 350 DVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMXTCTFKF 520
D+ N + R+ NG+V + RL + M L N+P D+ TCT +
Sbjct: 90 DLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLILSCLMDLKNFPMDIQTCTMQL 149
Query: 521 GS 526
S
Sbjct: 150 ES 151
>BC074795-1|AAH74795.1| 467|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, gamma 2 protein.
Length = 467
Score = 37.9 bits (84), Expect = 0.048
Identities = 25/90 (27%), Positives = 38/90 (42%), Gaps = 3/90 (3%)
Frame = +2
Query: 266 WIDKRLXWNAGEWGCXTWLVSSERLWRPDVVLLNAAATTAGDYAL---RARVSNNGSVSW 436
W D+RL +N+ ++W PD N+ A R+ N+G V +
Sbjct: 121 WYDRRLKFNSTIKVLRLNSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLY 180
Query: 437 IKRLDISTPISMQLDNWPNDMXTCTFKFGS 526
RL I +QL N+P D +C +F S
Sbjct: 181 TLRLTIDAECQLQLHNFPMDEHSCPLEFSS 210
>BC069348-1|AAH69348.1| 467|Homo sapiens gamma-aminobutyric acid A
receptor, gamma 2, isoform 2 precursor protein.
Length = 467
Score = 37.9 bits (84), Expect = 0.048
Identities = 25/90 (27%), Positives = 38/90 (42%), Gaps = 3/90 (3%)
Frame = +2
Query: 266 WIDKRLXWNAGEWGCXTWLVSSERLWRPDVVLLNAAATTAGDYAL---RARVSNNGSVSW 436
W D+RL +N+ ++W PD N+ A R+ N+G V +
Sbjct: 121 WYDRRLKFNSTIKVLRLNSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLY 180
Query: 437 IKRLDISTPISMQLDNWPNDMXTCTFKFGS 526
RL I +QL N+P D +C +F S
Sbjct: 181 TLRLTIDAECQLQLHNFPMDEHSCPLEFSS 210
>BC059389-1|AAH59389.1| 475|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, gamma 2 protein.
Length = 475
Score = 37.9 bits (84), Expect = 0.048
Identities = 25/90 (27%), Positives = 38/90 (42%), Gaps = 3/90 (3%)
Frame = +2
Query: 266 WIDKRLXWNAGEWGCXTWLVSSERLWRPDVVLLNAAATTAGDYAL---RARVSNNGSVSW 436
W D+RL +N+ ++W PD N+ A R+ N+G V +
Sbjct: 121 WYDRRLKFNSTIKVLRLNSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLY 180
Query: 437 IKRLDISTPISMQLDNWPNDMXTCTFKFGS 526
RL I +QL N+P D +C +F S
Sbjct: 181 TLRLTIDAECQLQLHNFPMDEHSCPLEFSS 210
>BC031087-1|AAH31087.1| 465|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, gamma 1 protein.
Length = 465
Score = 37.9 bits (84), Expect = 0.048
Identities = 28/103 (27%), Positives = 44/103 (42%), Gaps = 3/103 (2%)
Frame = +2
Query: 227 ESTVRILADLQMNWIDKRLXWNAGEWGCXTWLVSSERLWRPDVVLLNAAATTAGDYALR- 403
E T+ I+ W D RL +N+ ++W PD N+ + A
Sbjct: 108 EYTIDII--FAQTWFDSRLKFNSTMKVLMLNSNMVGKIWIPDTFFRNSRKSDAHWITTPN 165
Query: 404 --ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMXTCTFKFGS 526
R+ N+G V + RL I+ +QL N+P D +C +F S
Sbjct: 166 RLLRIWNDGRVLYTLRLTINAECYLQLHNFPMDEHSCPLEFSS 208
>AL049610-1|CAI42158.1| 376|Homo sapiens glycine receptor, alpha 4
protein.
Length = 376
Score = 37.9 bits (84), Expect = 0.048
Identities = 30/122 (24%), Positives = 52/122 (42%), Gaps = 7/122 (5%)
Frame = +2
Query: 182 VNLTLHL---RHANIRESESTVRILADLQMNWIDKRLXWNAGEWGCXTWLVSS-ERLWRP 349
VN+T ++ ++I ++ R+ L+ W D RL + S + +W+P
Sbjct: 30 VNVTCNIFINSFSSITKTTMDYRVNVFLRQQWNDPRLSYREYPDDSLDLDPSMLDSIWKP 89
Query: 350 DVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMXTCTFKF 520
D+ N + R+ NG+V + RL + M L N+P D+ TCT +
Sbjct: 90 DLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLILSCLMDLKNFPMDIQTCTMQL 149
Query: 521 GS 526
S
Sbjct: 150 ES 151
>AF165124-1|AAD50273.1| 467|Homo sapiens gamma-aminobutyric acid A
receptor gamma 2 protein.
Length = 467
Score = 37.9 bits (84), Expect = 0.048
Identities = 25/90 (27%), Positives = 38/90 (42%), Gaps = 3/90 (3%)
Frame = +2
Query: 266 WIDKRLXWNAGEWGCXTWLVSSERLWRPDVVLLNAAATTAGDYAL---RARVSNNGSVSW 436
W D+RL +N+ ++W PD N+ A R+ N+G V +
Sbjct: 121 WYDRRLKFNSTIKVLRLNSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLY 180
Query: 437 IKRLDISTPISMQLDNWPNDMXTCTFKFGS 526
RL I +QL N+P D +C +F S
Sbjct: 181 TLRLTIDAECQLQLHNFPMDEHSCPLEFSS 210
>X15376-1|CAA33437.1| 467|Homo sapiens GABA-A receptor gamma 2
subunit protein.
Length = 467
Score = 37.5 bits (83), Expect = 0.063
Identities = 25/90 (27%), Positives = 38/90 (42%), Gaps = 3/90 (3%)
Frame = +2
Query: 266 WIDKRLXWNAGEWGCXTWLVSSERLWRPDVVLLNAAATTAGDYAL---RARVSNNGSVSW 436
W D+RL +N+ ++W PD N+ A R+ N+G V +
Sbjct: 121 WYDRRLKFNSTIKVLRLNSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLY 180
Query: 437 IKRLDISTPISMQLDNWPNDMXTCTFKFGS 526
RL I +QL N+P D +C +F S
Sbjct: 181 SLRLTIDAECQLQLHNFPMDEHSCPLEFSS 210
>BC033801-1|AAH33801.1| 452|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, delta protein.
Length = 452
Score = 36.3 bits (80), Expect = 0.15
Identities = 29/129 (22%), Positives = 53/129 (41%), Gaps = 3/129 (2%)
Frame = +2
Query: 131 RSSQRTIGSLPPNSKIVVNLTLHLRHANIRESESTVRILADLQMNWIDKRLXWNAGEWGC 310
R+ + IG P N + + + + H + E T+ + L +W D RL +N
Sbjct: 53 RNFRPGIGGPPVNVALALEVA-SIDHISEANMEYTMTVF--LHQSWRDSRLSYNHTNETL 109
Query: 311 XTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLD 481
++LW PD ++NA + D + R+ +G + + R+ + M L
Sbjct: 110 GLDSRFVDKLWLPDTFIVNAKSAWFHDVTVENKLIRLQPDGVILYSIRITSTVACDMDLA 169
Query: 482 NWPNDMXTC 508
+P D C
Sbjct: 170 KYPMDEQEC 178
>AL391845-4|CAI15436.1| 452|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, delta protein.
Length = 452
Score = 36.3 bits (80), Expect = 0.15
Identities = 29/129 (22%), Positives = 53/129 (41%), Gaps = 3/129 (2%)
Frame = +2
Query: 131 RSSQRTIGSLPPNSKIVVNLTLHLRHANIRESESTVRILADLQMNWIDKRLXWNAGEWGC 310
R+ + IG P N + + + + H + E T+ + L +W D RL +N
Sbjct: 53 RNFRPGIGGPPVNVALALEVA-SIDHISEANMEYTMTVF--LHQSWRDSRLSYNHTNETL 109
Query: 311 XTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLD 481
++LW PD ++NA + D + R+ +G + + R+ + M L
Sbjct: 110 GLDSRFVDKLWLPDTFIVNAKSAWFHDVTVENKLIRLQPDGVILYSIRITSTVACDMDLA 169
Query: 482 NWPNDMXTC 508
+P D C
Sbjct: 170 KYPMDEQEC 178
>AF016917-1|AAB70007.1| 452|Homo sapiens GABA-A receptor delta
subunit protein.
Length = 452
Score = 36.3 bits (80), Expect = 0.15
Identities = 29/129 (22%), Positives = 53/129 (41%), Gaps = 3/129 (2%)
Frame = +2
Query: 131 RSSQRTIGSLPPNSKIVVNLTLHLRHANIRESESTVRILADLQMNWIDKRLXWNAGEWGC 310
R+ + IG P N + + + + H + E T+ + L +W D RL +N
Sbjct: 53 RNFRPGIGGPPVNVALALEVA-SIDHISEANMEYTMTVF--LHQSWRDSRLSYNHTNETL 109
Query: 311 XTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLD 481
++LW PD ++NA + D + R+ +G + + R+ + M L
Sbjct: 110 GLDSRFVDKLWLPDTFIVNAKSAWFHDVTVENKLIRLQPDGVILYSIRITSTVACDMDLA 169
Query: 482 NWPNDMXTC 508
+P D C
Sbjct: 170 KYPMDEQEC 178
>S82769-1|AAB39369.1| 467|Homo sapiens GABAA receptor gamma 3
subunit protein.
Length = 467
Score = 35.9 bits (79), Expect = 0.19
Identities = 24/90 (26%), Positives = 37/90 (41%), Gaps = 3/90 (3%)
Frame = +2
Query: 266 WIDKRLXWNAGEWGCXTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSW 436
W D RL +N+ +W PD + N+ A R+ N+G + +
Sbjct: 102 WTDSRLRFNSTMKILTLNSNMVGLIWIPDTIFRNSKTAEAHWITTPNQLLRIWNDGKILY 161
Query: 437 IKRLDISTPISMQLDNWPNDMXTCTFKFGS 526
RL I+ +QL N+P D +C F S
Sbjct: 162 TLRLTINAECQLQLHNFPMDEHSCPLIFSS 191
>AF269144-1|AAF99698.1| 467|Homo sapiens GABAA receptor gamma 3
subunit protein.
Length = 467
Score = 35.9 bits (79), Expect = 0.19
Identities = 24/90 (26%), Positives = 37/90 (41%), Gaps = 3/90 (3%)
Frame = +2
Query: 266 WIDKRLXWNAGEWGCXTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSW 436
W D RL +N+ +W PD + N+ A R+ N+G + +
Sbjct: 102 WTDSRLRFNSTMKILTLNSNMVGLIWIPDTIFRNSKTAEAHWITTPNQLLRIWNDGKILY 161
Query: 437 IKRLDISTPISMQLDNWPNDMXTCTFKFGS 526
RL I+ +QL N+P D +C F S
Sbjct: 162 TLRLTINAECQLQLHNFPMDEHSCPLIFSS 191
>AF228458-1|AAF63215.1| 449|Homo sapiens GABAA receptor gamma 3
subunit protein.
Length = 449
Score = 35.9 bits (79), Expect = 0.19
Identities = 24/90 (26%), Positives = 37/90 (41%), Gaps = 3/90 (3%)
Frame = +2
Query: 266 WIDKRLXWNAGEWGCXTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSW 436
W D RL +N+ +W PD + N+ A R+ N+G + +
Sbjct: 84 WTDSRLRFNSTMKILTLNSNMVGLIWIPDTIFRNSKTAEAHWITTPNQLLRIWNDGKILY 143
Query: 437 IKRLDISTPISMQLDNWPNDMXTCTFKFGS 526
RL I+ +QL N+P D +C F S
Sbjct: 144 TLRLTINAECQLQLHNFPMDEHSCPLIFSS 173
>BC109211-1|AAI09212.1| 632|Homo sapiens gamma-aminobutyric acid
(GABA) receptor, theta protein.
Length = 632
Score = 34.3 bits (75), Expect = 0.59
Identities = 26/101 (25%), Positives = 36/101 (35%), Gaps = 3/101 (2%)
Frame = +2
Query: 215 IRESESTVRILADLQMNWIDKRLXWNAGEWGCXTWLVSSERLWRPDVVLLNAAATTAGDY 394
I E I W D RL + E+LW PD LN+ D
Sbjct: 97 ISEMNMDYTITMFFHQTWKDSRLAYYETTLNLTLDYRMHEKLWVPDCYFLNSKDAFVHDV 156
Query: 395 ALRARVSN---NGSVSWIKRLDISTPISMQLDNWPNDMXTC 508
+ RV +G+V + RL + S+ L +P D C
Sbjct: 157 TVENRVFQLHPDGTVRYGIRLTTTAACSLDLHKFPMDKQAC 197
>BC109210-1|AAI09211.1| 632|Homo sapiens gamma-aminobutyric acid
(GABA) receptor, theta protein.
Length = 632
Score = 34.3 bits (75), Expect = 0.59
Identities = 26/101 (25%), Positives = 36/101 (35%), Gaps = 3/101 (2%)
Frame = +2
Query: 215 IRESESTVRILADLQMNWIDKRLXWNAGEWGCXTWLVSSERLWRPDVVLLNAAATTAGDY 394
I E I W D RL + E+LW PD LN+ D
Sbjct: 97 ISEMNMDYTITMFFHQTWKDSRLAYYETTLNLTLDYRMHEKLWVPDCYFLNSKDAFVHDV 156
Query: 395 ALRARVSN---NGSVSWIKRLDISTPISMQLDNWPNDMXTC 508
+ RV +G+V + RL + S+ L +P D C
Sbjct: 157 TVENRVFQLHPDGTVRYGIRLTTTAACSLDLHKFPMDKQAC 197
>AF189259-1|AAF70380.1| 632|Homo sapiens GABA-A receptor theta
subunit protein.
Length = 632
Score = 34.3 bits (75), Expect = 0.59
Identities = 26/101 (25%), Positives = 36/101 (35%), Gaps = 3/101 (2%)
Frame = +2
Query: 215 IRESESTVRILADLQMNWIDKRLXWNAGEWGCXTWLVSSERLWRPDVVLLNAAATTAGDY 394
I E I W D RL + E+LW PD LN+ D
Sbjct: 97 ISEMNMDYTITMFFHQTWKDSRLAYYETTLNLTLDYRMHEKLWVPDCYFLNSKDAFVHDV 156
Query: 395 ALRARVSN---NGSVSWIKRLDISTPISMQLDNWPNDMXTC 508
+ RV +G+V + RL + S+ L +P D C
Sbjct: 157 TVENRVFQLHPDGTVRYGIRLTTTAACSLDLHKFPMDKQAC 197
>AF144648-1|AAD51172.1| 627|Homo sapiens GABA-A receptor theta
protein.
Length = 627
Score = 34.3 bits (75), Expect = 0.59
Identities = 26/101 (25%), Positives = 36/101 (35%), Gaps = 3/101 (2%)
Frame = +2
Query: 215 IRESESTVRILADLQMNWIDKRLXWNAGEWGCXTWLVSSERLWRPDVVLLNAAATTAGDY 394
I E I W D RL + E+LW PD LN+ D
Sbjct: 92 ISEMNMDYTITMFFHQTWKDSRLAYYETTLNLTLDYRMHEKLWVPDCYFLNSKDAFVHDV 151
Query: 395 ALRARVSN---NGSVSWIKRLDISTPISMQLDNWPNDMXTC 508
+ RV +G+V + RL + S+ L +P D C
Sbjct: 152 TVENRVFQLHPDGTVRYGIRLTTTAACSLDLHKFPMDKQAC 192
>AB209359-1|BAD92596.1| 533|Homo sapiens cholinergic receptor,
nicotinic, alpha polypeptide 4 precursor variant
protein.
Length = 533
Score = 33.1 bits (72), Expect = 1.4
Identities = 19/74 (25%), Positives = 31/74 (41%)
Frame = +2
Query: 338 LWRPDVVLLNAAATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMXTCTFK 517
LW +A A + +A + ++G V W + S+ + +P D CT K
Sbjct: 25 LWLCCCTFTSADGDFAVTHLTKAHLFHDGRVQWTPPAIYKSSCSIDVTFFPFDQQNCTMK 84
Query: 518 FGSXMXNIDXMDFV 559
FGS + +D V
Sbjct: 85 FGSWTYDKAKIDLV 98
>BC096291-1|AAH96291.1| 556|Homo sapiens CHRNA4 protein protein.
Length = 556
Score = 32.3 bits (70), Expect = 2.4
Identities = 18/62 (29%), Positives = 30/62 (48%), Gaps = 4/62 (6%)
Frame = +2
Query: 386 GDYAL----RARVSNNGSVSWIKRLDISTPISMQLDNWPNDMXTCTFKFGSXMXNIDXMD 553
GD+A+ +A + ++G V W + S+ + +P D CT KFGS + +D
Sbjct: 60 GDFAVTHLTKAHLFHDGRVQWTPPAIYKSSCSIDVTFFPFDQQNCTMKFGSWTYDKAKID 119
Query: 554 FV 559
V
Sbjct: 120 LV 121
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 104,327,548
Number of Sequences: 237096
Number of extensions: 2119356
Number of successful extensions: 4674
Number of sequences better than 10.0: 159
Number of HSP's better than 10.0 without gapping: 4288
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4549
length of database: 76,859,062
effective HSP length: 90
effective length of database: 55,520,422
effective search space used: 11215125244
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
- SilkBase 1999-2023 -