Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BmNP06_FL5_L22
(859 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
AJ306454-1|CAC34819.1| 497|Homo sapiens neuronal nicotinic acet... 81 4e-15
Y08416-1|CAA69693.1| 498|Homo sapiens nicotinic acetylcholine r... 79 2e-14
U62439-1|AAB40117.1| 498|Homo sapiens nicotinic acetylcholine r... 79 2e-14
U48861-1|AAA92123.1| 498|Homo sapiens beta 4 nicotinic acetylch... 79 2e-14
BC096082-1|AAH96082.1| 498|Homo sapiens cholinergic receptor, n... 79 2e-14
BC096080-1|AAH96080.1| 498|Homo sapiens cholinergic receptor, n... 79 2e-14
AF306329-1|AAL02062.1| 498|Homo sapiens neuronal nicotinic acet... 79 2e-14
X68275-1|CAA48336.1| 451|Homo sapiens nicotinic receptor beta 4... 75 3e-13
Y08419-1|CAA69696.1| 468|Homo sapiens nicotinic acetylcholine r... 73 1e-12
U62434-1|AAB40112.1| 468|Homo sapiens nicotinic acetylcholine r... 73 1e-12
BC033639-1|AAH33639.1| 468|Homo sapiens cholinergic receptor, n... 73 1e-12
AJ306481-1|CAC34820.1| 468|Homo sapiens neuronal nicotinic acet... 73 1e-12
M83712-1|AAA58357.1| 468|Homo sapiens nicotinic receptor alpha ... 72 2e-12
Y08417-1|CAA69694.1| 458|Homo sapiens nicotinic acetylcholine r... 71 4e-12
X67513-1|CAA47851.1| 423|Homo sapiens nicotinic acetylcholine ... 71 4e-12
U62438-1|AAB40116.1| 458|Homo sapiens nicotinic acetylcholine r... 71 4e-12
BC069788-1|AAH69788.1| 458|Homo sapiens cholinergic receptor, n... 71 4e-12
BC069703-1|AAH69703.1| 458|Homo sapiens cholinergic receptor, n... 71 4e-12
BC069681-1|AAH69681.1| 458|Homo sapiens cholinergic receptor, n... 71 4e-12
AF140765-1|AAD33063.1| 458|Homo sapiens neuronal acetylcholine ... 71 4e-12
AJ001935-1|CAA05108.1| 504|Homo sapiens CHRNB2 protein. 71 7e-12
Y08415-1|CAA69692.1| 502|Homo sapiens nicotinic acetylcholine r... 70 9e-12
X53179-1|CAA37320.1| 502|Homo sapiens precursor peptide (AA -25... 70 9e-12
U62437-1|AAB40115.1| 502|Homo sapiens nicotinic acetylcholine r... 70 9e-12
BC075041-1|AAH75041.1| 502|Homo sapiens cholinergic receptor, n... 70 9e-12
BC075040-1|AAH75040.1| 502|Homo sapiens cholinergic receptor, n... 70 9e-12
AL592078-3|CAI16184.1| 502|Homo sapiens cholinergic receptor, n... 70 9e-12
AF077186-1|AAD45422.1| 502|Homo sapiens neuronal nicotinic acet... 70 9e-12
Y16281-1|CAA76154.1| 529|Homo sapiens nicotinic acetylcholine r... 69 2e-11
U62431-1|AAB40109.1| 529|Homo sapiens nicotinic acetylcholine r... 69 2e-11
Y08418-1|CAA69695.1| 503|Homo sapiens nicotinic acetylcholine r... 69 3e-11
X53559-1|CAA37625.1| 474|Homo sapiens neuronal nicotinic acetyl... 69 3e-11
U62432-1|AAB40110.1| 504|Homo sapiens nicotinic acetylcholine r... 69 3e-11
M37981-1|AAA59942.1| 503|Homo sapiens neuronal nicotinic acetyl... 69 3e-11
BT006897-1|AAP35543.1| 505|Homo sapiens cholinergic receptor, n... 69 3e-11
BT006646-1|AAP35292.1| 489|Homo sapiens cholinergic receptor, n... 69 3e-11
BC098443-1|AAH98443.1| 504|Homo sapiens cholinergic receptor, n... 69 3e-11
BC006114-1|AAH06114.1| 489|Homo sapiens CHRNA3 protein protein. 69 3e-11
BC002996-1|AAH02996.1| 505|Homo sapiens cholinergic receptor, n... 69 3e-11
BC001642-1|AAH01642.1| 505|Homo sapiens cholinergic receptor, n... 69 3e-11
BC000513-1|AAH00513.1| 505|Homo sapiens cholinergic receptor, n... 69 3e-11
AJ007783-1|CAA07682.1| 504|Homo sapiens nicotinic acetylcholine... 69 3e-11
AF385584-1|AAK68110.1| 489|Homo sapiens nicotinic cholinergic r... 69 3e-11
Y16282-1|CAA76155.1| 494|Homo sapiens nicotinic acetylcholine r... 68 4e-11
U62435-1|AAB40113.1| 494|Homo sapiens nicotinic acetylcholine r... 68 4e-11
BC014456-1|AAH14456.1| 494|Homo sapiens cholinergic receptor, n... 68 4e-11
AB079251-1|BAC06855.1| 494|Homo sapiens Nicotinic acetylcholine... 68 4e-11
M86383-1|AAC84176.1| 502|Homo sapiens nicotinic acetylcholine r... 66 2e-10
Y08421-1|CAA69698.1| 627|Homo sapiens nicotinic acetylcholine r... 64 6e-10
X89741-1|CAA61893.1| 627|Homo sapiens neuronal acetylcholine re... 64 6e-10
X87629-1|CAA60959.1| 602|Homo sapiens nicotinic acetylcholine r... 64 6e-10
X66403-1|CAA47030.1| 493|Homo sapiens acetylcholine receptor ep... 64 6e-10
U62433-1|AAB40111.1| 627|Homo sapiens nicotinic acetylcholine r... 64 6e-10
L35901-1|AAA64743.1| 627|Homo sapiens nicotinic acetylcholine r... 64 6e-10
DQ093071-1|AAY88737.1| 627|Homo sapiens cholinergic receptor, n... 64 6e-10
BC096290-1|AAH96290.1| 627|Homo sapiens cholinergic receptor, n... 64 6e-10
AF105999-1|AAD24503.1| 493|Homo sapiens acetylcholine receptor ... 64 6e-10
X14830-1|CAA32939.1| 501|Homo sapiens protein ( Human mRNA for ... 62 2e-09
BC011371-1|AAH11371.1| 501|Homo sapiens cholinergic receptor, n... 62 2e-09
X01715-1|CAA25861.1| 520|Homo sapiens acetylcholine receptor ga... 62 3e-09
AC092165-3|AAY24103.1| 520|Homo sapiens unknown protein. 62 3e-09
BC023553-1|AAH23553.1| 501|Homo sapiens cholinergic receptor, n... 61 4e-09
DQ644022-1|ABG35128.1| 456|Homo sapiens 5-HT3 receptor subunit ... 61 6e-09
BC101183-1|AAI01184.1| 471|Homo sapiens 5-hydroxytryptamine (se... 61 6e-09
BC101182-1|AAI01183.1| 471|Homo sapiens 5-hydroxytryptamine (se... 61 6e-09
AY159813-1|AAO38167.2| 471|Homo sapiens 5-hydroxytryptamine ser... 61 6e-09
Y00762-1|CAA68731.1| 457|Homo sapiens protein ( Human mRNA for ... 60 1e-08
X02502-1|CAA26344.1| 457|Homo sapiens acetylcholine receptor pr... 60 1e-08
S77094-1|AAD14247.1| 457|Homo sapiens nicotinic acetylcholine r... 60 1e-08
BC006314-1|AAH06314.1| 269|Homo sapiens CHRNA1 protein protein. 60 1e-08
AC018890-1|AAY14687.1| 457|Homo sapiens unknown protein. 60 1e-08
AY349353-1|AAQ93477.1| 456|Homo sapiens 5-HT3c1 serotonin recep... 59 2e-08
AY349352-1|AAQ93476.1| 441|Homo sapiens 5-HT3c1 serotonin recep... 59 2e-08
Z23141-1|CAA80672.1| 479|Homo sapiens cholinergic receptor, nic... 58 4e-08
Y08420-1|CAA69697.1| 502|Homo sapiens nicotinic acetylcholine r... 58 4e-08
X70297-1|CAA49778.1| 502|Homo sapiens neuronal nicotinic acetyl... 58 4e-08
U62436-1|AAB40114.1| 502|Homo sapiens nicotinic acetylcholine r... 58 4e-08
AJ586911-1|CAE52911.1| 502|Homo sapiens nicotinic acetylcholine... 58 4e-08
AJ295237-1|CAC16144.1| 450|Homo sapiens neuronal nicotinic acet... 58 4e-08
AJ278118-1|CAC20435.1| 450|Homo sapiens neuronal nicotinic acet... 58 4e-08
AF327367-1|AAK14333.1| 450|Homo sapiens nicotinic acetylcholine... 58 4e-08
AF199235-1|AAG00795.2| 450|Homo sapiens nicotinic acetylcholine... 58 4e-08
BC113575-1|AAI13576.1| 479|Homo sapiens cholinergic receptor, n... 58 5e-08
BC113549-1|AAI13550.1| 479|Homo sapiens cholinergic receptor, n... 58 5e-08
AY123244-1|AAM74523.1| 479|Homo sapiens nicotinic acetylcholine... 58 5e-08
AJ243342-1|CAB65091.1| 479|Homo sapiens nicotinic acetylcholine... 58 5e-08
AC118275-1|AAY40986.1| 479|Homo sapiens unknown protein. 58 5e-08
X55019-1|CAA38759.1| 517|Homo sapiens acetylcholine receptor de... 57 7e-08
BC101185-1|AAI01186.1| 374|Homo sapiens HTR3E protein protein. 57 7e-08
BC093925-1|AAH93925.1| 517|Homo sapiens cholinergic receptor, n... 57 7e-08
BC093923-1|AAH93923.1| 517|Homo sapiens cholinergic receptor, n... 57 7e-08
AC092165-2|AAY24102.1| 517|Homo sapiens unknown protein. 57 7e-08
BC131799-1|AAI31800.1| 447|Homo sapiens 5-hydroxytryptamine (se... 57 9e-08
U40583-1|AAA83561.1| 502|Homo sapiens alpha 7 neuronal nicotini... 56 1e-07
AF459285-1|AAL66182.1| 447|Homo sapiens 5-hydroxytryptamine rec... 56 1e-07
AF385585-1|AAK68111.1| 502|Homo sapiens nicotinic cholinergic r... 56 1e-07
AF227732-1|AAF61920.1| 470|Homo sapiens nicotinic acetylcholine... 56 1e-07
S77554-1|AAB33983.1| 474|Homo sapiens GABAA receptor beta 2 sub... 55 3e-07
S77553-1|AAB33982.1| 512|Homo sapiens GABAA receptor beta 2 sub... 55 3e-07
S67368-1|AAB29370.1| 474|Homo sapiens gamma-aminobutyric acid A... 55 3e-07
BC105639-1|AAI05640.1| 474|Homo sapiens GABRB2 protein protein. 55 3e-07
BC099719-1|AAH99719.1| 474|Homo sapiens GABRB2 protein protein. 55 3e-07
BC099705-1|AAH99705.1| 474|Homo sapiens GABRB2 protein protein. 55 3e-07
L08485-1|AAA58490.1| 462|Homo sapiens GABA-benzodiazepine recep... 55 4e-07
BT009830-1|AAP88832.1| 462|Homo sapiens gamma-aminobutyric acid... 55 4e-07
BC113422-1|AAI13423.1| 462|Homo sapiens gamma-aminobutyric acid... 55 4e-07
BC111979-1|AAI11980.1| 462|Homo sapiens gamma-aminobutyric acid... 55 4e-07
BC110597-1|AAI10598.1| 411|Homo sapiens ligand-gated ion channe... 54 5e-07
AF512521-1|AAO20969.1| 411|Homo sapiens ligand-gated ion channe... 54 5e-07
AB223030-1|BAE19924.1| 411|Homo sapiens ligand-gated ion-channe... 54 7e-07
BC111802-1|AAI11803.1| 465|Homo sapiens CHRNG protein protein. 53 2e-06
BC028629-1|AAH28629.1| 492|Homo sapiens gamma-aminobutyric acid... 52 3e-06
S62908-1|AAB27279.1| 492|Homo sapiens gamma-aminobutyric acidA ... 52 4e-06
AF166361-1|AAG12455.1| 492|Homo sapiens GABA receptor subunit a... 52 4e-06
M59216-1|AAA35862.1| 474|Homo sapiens gamma-aminobutyric acid r... 51 6e-06
AK122638-1|BAC85499.1| 266|Homo sapiens yte protein of 76kDa) (... 51 6e-06
S82769-1|AAB39369.1| 467|Homo sapiens GABAA receptor gamma 3 su... 50 8e-06
AF269144-1|AAF99698.1| 467|Homo sapiens GABAA receptor gamma 3 ... 50 8e-06
AF228458-1|AAF63215.1| 449|Homo sapiens GABAA receptor gamma 3 ... 50 8e-06
X14767-1|CAA32875.1| 474|Homo sapiens GABA-A receptor beta 1 su... 50 1e-05
AJ003080-1|CAA05853.1| 238|Homo sapiens serotonin receptor prot... 50 1e-05
S82612-1|AAB37533.2| 478|Homo sapiens 5-hydroxytryptamine type ... 50 1e-05
S81944-1|AAB36480.1| 453|Homo sapiens gamma-aminobutyric acid t... 49 2e-05
D49394-1|BAA08387.1| 478|Homo sapiens serotonin 5-HT3 receptor ... 49 2e-05
BT007204-1|AAP35868.1| 484|Homo sapiens 5-hydroxytryptamine (se... 49 2e-05
BC099641-1|AAH99641.1| 453|Homo sapiens gamma-aminobutyric acid... 49 2e-05
BC099640-1|AAH99640.1| 453|Homo sapiens gamma-aminobutyric acid... 49 2e-05
BC096242-1|AAH96242.1| 453|Homo sapiens gamma-aminobutyric acid... 49 2e-05
BC096241-1|AAH96241.1| 453|Homo sapiens gamma-aminobutyric acid... 49 2e-05
BC004453-1|AAH04453.2| 478|Homo sapiens 5-hydroxytryptamine (se... 49 2e-05
BC002354-1|AAH02354.1| 478|Homo sapiens 5-hydroxytryptamine (se... 49 2e-05
AJ005205-1|CAA06442.3| 478|Homo sapiens serotonin 3 receptor pr... 49 2e-05
AJ003079-1|CAA05852.1| 478|Homo sapiens 5-hydroxytryptamine3 re... 49 2e-05
AJ003078-1|CAA05851.1| 510|Homo sapiens serotonin receptor prot... 49 2e-05
AF498984-1|AAM21131.1| 478|Homo sapiens 5-hydroxytryptamine rec... 49 2e-05
U30461-1|AAB52519.1| 554|Homo sapiens GABAA receptor subunit al... 49 3e-05
BC035055-1|AAH35055.1| 554|Homo sapiens gamma-aminobutyric acid... 49 3e-05
U77731-2|AAB38273.1| 360|Homo sapiens glycine receptor alpha 2B... 48 3e-05
CR450343-1|CAG29339.1| 452|Homo sapiens GLRA2 protein. 48 3e-05
AY437084-1|AAR87843.1| 452|Homo sapiens glycine receptor alpha2... 48 3e-05
X52008-1|CAA36257.1| 452|Homo sapiens inhibitory glycine recept... 48 4e-05
U77731-1|AAB38272.1| 360|Homo sapiens glycine receptor alpha 2 ... 48 4e-05
BC032864-1|AAH32864.1| 452|Homo sapiens glycine receptor, alpha... 48 4e-05
AY437083-1|AAR87842.1| 452|Homo sapiens glycine receptor alpha2... 48 4e-05
AF053495-1|AAC35290.1| 452|Homo sapiens glycine receptor alpha ... 48 4e-05
BC096083-1|AAH96083.1| 198|Homo sapiens CHRNB4 protein protein. 48 6e-05
BC096081-1|AAH96081.1| 198|Homo sapiens CHRNB4 protein protein. 48 6e-05
BC033801-1|AAH33801.1| 452|Homo sapiens gamma-aminobutyric acid... 47 8e-05
AL391845-4|CAI15436.1| 452|Homo sapiens gamma-aminobutyric acid... 47 8e-05
AF016917-1|AAB70007.1| 452|Homo sapiens GABA-A receptor delta s... 47 8e-05
U95367-1|AAC51357.1| 440|Homo sapiens GABA-A receptor pi subuni... 47 1e-04
BC109106-1|AAI09107.1| 440|Homo sapiens gamma-aminobutyric acid... 47 1e-04
BC109105-1|AAI09106.1| 440|Homo sapiens gamma-aminobutyric acid... 47 1e-04
BC074865-1|AAH74865.1| 440|Homo sapiens gamma-aminobutyric acid... 47 1e-04
BC074810-1|AAH74810.1| 440|Homo sapiens gamma-aminobutyric acid... 47 1e-04
AF009702-1|AAC24194.1| 440|Homo sapiens GABA-A receptor pi subu... 47 1e-04
X52009-1|CAA36258.1| 449|Homo sapiens inhibitory glycine recept... 46 2e-04
BC114947-1|AAI14948.1| 457|Homo sapiens GLRA1 protein protein. 46 2e-04
BC109211-1|AAI09212.1| 632|Homo sapiens gamma-aminobutyric acid... 46 2e-04
BC109210-1|AAI09211.1| 632|Homo sapiens gamma-aminobutyric acid... 46 2e-04
BC074980-1|AAH74980.1| 449|Homo sapiens glycine receptor, alpha... 46 2e-04
AF189259-1|AAF70380.1| 632|Homo sapiens GABA-A receptor theta s... 46 2e-04
AF144648-1|AAD51172.1| 627|Homo sapiens GABA-A receptor theta p... 46 2e-04
BC022449-1|AAH22449.1| 474|Homo sapiens gamma-aminobutyric acid... 46 2e-04
BC031087-1|AAH31087.1| 465|Homo sapiens gamma-aminobutyric acid... 44 5e-04
U93917-1|AAC39917.1| 449|Homo sapiens glycine receptor alpha 3 ... 44 7e-04
BC036086-1|AAH36086.1| 464|Homo sapiens glycine receptor, alpha... 44 7e-04
AF017724-1|AAC39919.1| 465|Homo sapiens glycine receptor alpha ... 44 7e-04
BC114967-1|AAI14968.1| 366|Homo sapiens GLRA1 protein protein. 44 0.001
BC074795-1|AAH74795.1| 467|Homo sapiens gamma-aminobutyric acid... 44 0.001
BC069348-1|AAH69348.1| 467|Homo sapiens gamma-aminobutyric acid... 44 0.001
BC059389-1|AAH59389.1| 475|Homo sapiens gamma-aminobutyric acid... 44 0.001
AF165124-1|AAD50273.1| 467|Homo sapiens gamma-aminobutyric acid... 44 0.001
X15376-1|CAA33437.1| 467|Homo sapiens GABA-A receptor gamma 2 s... 42 0.002
Z93848-1|CAI41994.1| 376|Homo sapiens glycine receptor, alpha 4... 42 0.003
AL049610-1|CAI42158.1| 376|Homo sapiens glycine receptor, alpha... 42 0.003
AB209359-1|BAD92596.1| 533|Homo sapiens cholinergic receptor, n... 39 0.020
BC096291-1|AAH96291.1| 556|Homo sapiens CHRNA4 protein protein. 38 0.035
U83981-1|AAC25631.1| 674|Homo sapiens apoptosis associated prot... 31 5.4
CR457259-1|CAG33540.1| 674|Homo sapiens PPP1R15A protein. 31 5.4
BC003067-1|AAH03067.1| 674|Homo sapiens protein phosphatase 1, ... 31 5.4
AK001361-1|BAA91649.1| 674|Homo sapiens protein ( Homo sapiens ... 31 5.4
BC146774-1|AAI46775.1| 1114|Homo sapiens GPR124 protein protein. 31 7.1
AY181242-1|AAO27354.1| 1331|Homo sapiens G protein-coupled recep... 31 7.1
AK074099-1|BAB84925.1| 1310|Homo sapiens FLJ00170 protein protein. 31 7.1
AF378755-1|AAL11992.1| 1331|Homo sapiens tumor endothelial marke... 31 7.1
AB040964-1|BAA96055.2| 1206|Homo sapiens KIAA1531 protein protein. 31 7.1
AK122582-1|BAC56923.1| 1383|Homo sapiens FLJ00269 protein protein. 30 9.4
>AJ306454-1|CAC34819.1| 497|Homo sapiens neuronal nicotinic
acetylcholine receptor beta-4 subunit protein.
Length = 497
Score = 81.4 bits (192), Expect = 4e-15
Identities = 54/192 (28%), Positives = 90/192 (46%), Gaps = 11/192 (5%)
Frame = +3
Query: 93 AIASAAECENATSLSLMIDSLL--ATYD---RDSPPDSKIV-VNLTLHLRHA-NIRESES 251
A+ C A + ++D LL Y+ R + S+++ + L L L ++ E E
Sbjct: 14 ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQ 73
Query: 252 TVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRAR 428
+ L+ W D RL+WN+ + G + + ++R+W PD+VL N T
Sbjct: 74 IMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNDGTYEVSVYTNLI 133
Query: 429 VSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCAFKFGSRMHNSDEMDFVIDXRIYSMFE 608
V +NGSV W+ + +++ +P D Q C KF S ++ E+D V+ SM +
Sbjct: 134 VRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRSWTYDHTEIDMVLMTPTASMDD 193
Query: 609 ---SGXWDVTAL 635
SG WD+ AL
Sbjct: 194 FTPSGEWDIVAL 205
>Y08416-1|CAA69693.1| 498|Homo sapiens nicotinic acetylcholine
receptor beta4 subunit precursor protein.
Length = 498
Score = 79.4 bits (187), Expect = 2e-14
Identities = 55/193 (28%), Positives = 91/193 (47%), Gaps = 12/193 (6%)
Frame = +3
Query: 93 AIASAAECENATSLSLMIDSLL--ATYD---RDSPPDSKIV-VNLTLHLRHA-NIRESES 251
A+ C A + ++D LL Y+ R + S+++ + L L L ++ E E
Sbjct: 14 ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQ 73
Query: 252 TVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRA 425
+ L+ W D RL+WN+ + G + + ++R+W PD+VL N A T
Sbjct: 74 IMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNADGTYEVSVYTNL 133
Query: 426 RVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCAFKFGSRMHNSDEMDFVIDXRIYSMF 605
V +NGSV W+ + +++ +P D Q C KF S ++ E+D V+ SM
Sbjct: 134 IVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRSWTYDHTEIDMVLMTPTASMD 193
Query: 606 E---SGXWDVTAL 635
+ SG WD+ AL
Sbjct: 194 DFTPSGEWDIVAL 206
>U62439-1|AAB40117.1| 498|Homo sapiens nicotinic acetylcholine
receptor beta4 subunit precursor protein.
Length = 498
Score = 79.4 bits (187), Expect = 2e-14
Identities = 55/193 (28%), Positives = 91/193 (47%), Gaps = 12/193 (6%)
Frame = +3
Query: 93 AIASAAECENATSLSLMIDSLL--ATYD---RDSPPDSKIV-VNLTLHLRHA-NIRESES 251
A+ C A + ++D LL Y+ R + S+++ + L L L ++ E E
Sbjct: 14 ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQ 73
Query: 252 TVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRA 425
+ L+ W D RL+WN+ + G + + ++R+W PD+VL N A T
Sbjct: 74 IMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNADGTYEVSVYTNL 133
Query: 426 RVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCAFKFGSRMHNSDEMDFVIDXRIYSMF 605
V +NGSV W+ + +++ +P D Q C KF S ++ E+D V+ SM
Sbjct: 134 IVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRSWTYDHTEIDMVLMTPTASMD 193
Query: 606 E---SGXWDVTAL 635
+ SG WD+ AL
Sbjct: 194 DFTPSGEWDIVAL 206
>U48861-1|AAA92123.1| 498|Homo sapiens beta 4 nicotinic
acetylcholine receptor subunit protein.
Length = 498
Score = 79.4 bits (187), Expect = 2e-14
Identities = 55/193 (28%), Positives = 91/193 (47%), Gaps = 12/193 (6%)
Frame = +3
Query: 93 AIASAAECENATSLSLMIDSLL--ATYD---RDSPPDSKIV-VNLTLHLRHA-NIRESES 251
A+ C A + ++D LL Y+ R + S+++ + L L L ++ E E
Sbjct: 14 ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQ 73
Query: 252 TVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRA 425
+ L+ W D RL+WN+ + G + + ++R+W PD+VL N A T
Sbjct: 74 IMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNADGTYEVSVYTNL 133
Query: 426 RVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCAFKFGSRMHNSDEMDFVIDXRIYSMF 605
V +NGSV W+ + +++ +P D Q C KF S ++ E+D V+ SM
Sbjct: 134 IVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRSWTYDHTEIDMVLMTPTASMD 193
Query: 606 E---SGXWDVTAL 635
+ SG WD+ AL
Sbjct: 194 DFTPSGEWDIVAL 206
>BC096082-1|AAH96082.1| 498|Homo sapiens cholinergic receptor,
nicotinic, beta 4 protein.
Length = 498
Score = 79.4 bits (187), Expect = 2e-14
Identities = 55/193 (28%), Positives = 91/193 (47%), Gaps = 12/193 (6%)
Frame = +3
Query: 93 AIASAAECENATSLSLMIDSLL--ATYD---RDSPPDSKIV-VNLTLHLRHA-NIRESES 251
A+ C A + ++D LL Y+ R + S+++ + L L L ++ E E
Sbjct: 14 ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQ 73
Query: 252 TVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRA 425
+ L+ W D RL+WN+ + G + + ++R+W PD+VL N A T
Sbjct: 74 IMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNADGTYEVSVYTNL 133
Query: 426 RVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCAFKFGSRMHNSDEMDFVIDXRIYSMF 605
V +NGSV W+ + +++ +P D Q C KF S ++ E+D V+ SM
Sbjct: 134 IVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRSWTYDHTEIDMVLMTPTASMD 193
Query: 606 E---SGXWDVTAL 635
+ SG WD+ AL
Sbjct: 194 DFTPSGEWDIVAL 206
>BC096080-1|AAH96080.1| 498|Homo sapiens cholinergic receptor,
nicotinic, beta 4 protein.
Length = 498
Score = 79.4 bits (187), Expect = 2e-14
Identities = 55/193 (28%), Positives = 91/193 (47%), Gaps = 12/193 (6%)
Frame = +3
Query: 93 AIASAAECENATSLSLMIDSLL--ATYD---RDSPPDSKIV-VNLTLHLRHA-NIRESES 251
A+ C A + ++D LL Y+ R + S+++ + L L L ++ E E
Sbjct: 14 ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQ 73
Query: 252 TVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRA 425
+ L+ W D RL+WN+ + G + + ++R+W PD+VL N A T
Sbjct: 74 IMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNADGTYEVSVYTNL 133
Query: 426 RVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCAFKFGSRMHNSDEMDFVIDXRIYSMF 605
V +NGSV W+ + +++ +P D Q C KF S ++ E+D V+ SM
Sbjct: 134 IVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRSWTYDHTEIDMVLMTPTASMD 193
Query: 606 E---SGXWDVTAL 635
+ SG WD+ AL
Sbjct: 194 DFTPSGEWDIVAL 206
>AF306329-1|AAL02062.1| 498|Homo sapiens neuronal nicotinic
acetylcholine receptor beta 4 subunit protein.
Length = 498
Score = 79.4 bits (187), Expect = 2e-14
Identities = 55/193 (28%), Positives = 91/193 (47%), Gaps = 12/193 (6%)
Frame = +3
Query: 93 AIASAAECENATSLSLMIDSLL--ATYD---RDSPPDSKIV-VNLTLHLRHA-NIRESES 251
A+ C A + ++D LL Y+ R + S+++ + L L L ++ E E
Sbjct: 14 ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQ 73
Query: 252 TVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRA 425
+ L+ W D RL+WN+ + G + + ++R+W PD+VL N A T
Sbjct: 74 IMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNADGTYEVSVYTNL 133
Query: 426 RVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCAFKFGSRMHNSDEMDFVIDXRIYSMF 605
V +NGSV W+ + +++ +P D Q C KF S ++ E+D V+ SM
Sbjct: 134 IVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRSWTYDHTEIDMVLMTPTASMD 193
Query: 606 E---SGXWDVTAL 635
+ SG WD+ AL
Sbjct: 194 DFTPSGEWDIVAL 206
>X68275-1|CAA48336.1| 451|Homo sapiens nicotinic receptor beta 4
subunit protein.
Length = 451
Score = 75.4 bits (177), Expect = 3e-13
Identities = 46/153 (30%), Positives = 74/153 (48%), Gaps = 6/153 (3%)
Frame = +3
Query: 195 IVVNLTLHLRHA-NIRESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 368
I + L L L ++ E + + L+ W D RL+WN+ + G + + ++R+W P
Sbjct: 7 ISIKLQLSLAQLISVNERDEIMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLP 66
Query: 369 DVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCAFKFGS 545
D+VL N A T V +NGSV W+ + +++ +P D Q C KF S
Sbjct: 67 DIVLYNNADGTYEVSVYTNLIVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRS 126
Query: 546 RMHNSDEMDFVIDXRIYSMFE---SGXWDVTAL 635
++ E+D V+ SM + SG WD+ AL
Sbjct: 127 WTYDHTEIDMVLMTPTASMDDFTPSGEWDIVAL 159
>Y08419-1|CAA69696.1| 468|Homo sapiens nicotinic acetylcholine
receptor alpha5 subunit precursor protein.
Length = 468
Score = 73.3 bits (172), Expect = 1e-12
Identities = 41/177 (23%), Positives = 84/177 (47%), Gaps = 9/177 (5%)
Frame = +3
Query: 141 MIDSLLATYDRDSPP----DSKIVVNLTLHLRH-ANIRESESTVRIQADLQMNWIDKRLS 305
++ L Y+R P + KI + L + ++ E + L+ WID +L
Sbjct: 50 LLKDLFQDYERWVRPVEHLNDKIKIKFGLAISQLVDVDEKNQLMTTNVWLKQEWIDVKLR 109
Query: 306 WNAGEWG-CSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVSWIKRLDISTP 482
WN ++G V S+ +W PD+VL + A + + + NG+V+W + +
Sbjct: 110 WNPDDYGGIKVIRVPSDSVWTPDIVLFDNADGRFEGTSTKTVIRYNGTVTWTPPANYKSS 169
Query: 483 ISMQLDNWPNDMQTCAFKFGSRMHNSDEMDFVI---DXRIYSMFESGXWDVTALSSA 644
++ + +P D+Q C+ KFGS ++ ++D ++ D F++G W++ + + +
Sbjct: 170 CTIDVTFFPFDLQNCSMKFGSWTYDGSQVDIILEDQDVDKRDFFDNGEWEIVSATGS 226
>U62434-1|AAB40112.1| 468|Homo sapiens nicotinic acetylcholine
receptor alpha5 subunit precursor protein.
Length = 468
Score = 73.3 bits (172), Expect = 1e-12
Identities = 41/177 (23%), Positives = 84/177 (47%), Gaps = 9/177 (5%)
Frame = +3
Query: 141 MIDSLLATYDRDSPP----DSKIVVNLTLHLRH-ANIRESESTVRIQADLQMNWIDKRLS 305
++ L Y+R P + KI + L + ++ E + L+ WID +L
Sbjct: 50 LLKDLFQDYERWVRPVEHLNDKIKIKFGLAISQLVDVDEKNQLMTTNVWLKQEWIDVKLR 109
Query: 306 WNAGEWG-CSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVSWIKRLDISTP 482
WN ++G V S+ +W PD+VL + A + + + NG+V+W + +
Sbjct: 110 WNPDDYGGIKVIRVPSDSVWTPDIVLFDNADGRFEGTSTKTVIRYNGTVTWTPPANYKSS 169
Query: 483 ISMQLDNWPNDMQTCAFKFGSRMHNSDEMDFVI---DXRIYSMFESGXWDVTALSSA 644
++ + +P D+Q C+ KFGS ++ ++D ++ D F++G W++ + + +
Sbjct: 170 CTIDVTFFPFDLQNCSMKFGSWTYDGSQVDIILEDQDVDKRDFFDNGEWEIVSATGS 226
>BC033639-1|AAH33639.1| 468|Homo sapiens cholinergic receptor,
nicotinic, alpha 5 protein.
Length = 468
Score = 73.3 bits (172), Expect = 1e-12
Identities = 41/177 (23%), Positives = 84/177 (47%), Gaps = 9/177 (5%)
Frame = +3
Query: 141 MIDSLLATYDRDSPP----DSKIVVNLTLHLRH-ANIRESESTVRIQADLQMNWIDKRLS 305
++ L Y+R P + KI + L + ++ E + L+ WID +L
Sbjct: 50 LLKDLFQDYERWVRPVEHLNDKIKIKFGLAISQLVDVDEKNQLMTTNVWLKQEWIDVKLR 109
Query: 306 WNAGEWG-CSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVSWIKRLDISTP 482
WN ++G V S+ +W PD+VL + A + + + NG+V+W + +
Sbjct: 110 WNPDDYGGIKVIRVPSDSVWTPDIVLFDNADGRFEGTSTKTVIRYNGTVTWTPPANYKSS 169
Query: 483 ISMQLDNWPNDMQTCAFKFGSRMHNSDEMDFVI---DXRIYSMFESGXWDVTALSSA 644
++ + +P D+Q C+ KFGS ++ ++D ++ D F++G W++ + + +
Sbjct: 170 CTIDVTFFPFDLQNCSMKFGSWTYDGSQVDIILEDQDVDKRDFFDNGEWEIVSATGS 226
>AJ306481-1|CAC34820.1| 468|Homo sapiens neuronal nicotinic
acetylcholine receptor alpha-5subunit protein.
Length = 468
Score = 73.3 bits (172), Expect = 1e-12
Identities = 41/177 (23%), Positives = 84/177 (47%), Gaps = 9/177 (5%)
Frame = +3
Query: 141 MIDSLLATYDRDSPP----DSKIVVNLTLHLRH-ANIRESESTVRIQADLQMNWIDKRLS 305
++ L Y+R P + KI + L + ++ E + L+ WID +L
Sbjct: 50 LLKDLFQDYERWVRPVEHLNDKIKIKFGLAISQLVDVDEKNQLMTTNVWLKQEWIDVKLR 109
Query: 306 WNAGEWG-CSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVSWIKRLDISTP 482
WN ++G V S+ +W PD+VL + A + + + NG+V+W + +
Sbjct: 110 WNPDDYGGIKVIRVPSDSVWTPDIVLFDNADGRFEGTSTKTVIRYNGTVTWTPPANYKSS 169
Query: 483 ISMQLDNWPNDMQTCAFKFGSRMHNSDEMDFVI---DXRIYSMFESGXWDVTALSSA 644
++ + +P D+Q C+ KFGS ++ ++D ++ D F++G W++ + + +
Sbjct: 170 CTIDVTFFPFDLQNCSMKFGSWTYDGSQVDIILEDQDVDKRDFFDNGEWEIVSATGS 226
>M83712-1|AAA58357.1| 468|Homo sapiens nicotinic receptor alpha 5
subunit protein.
Length = 468
Score = 72.1 bits (169), Expect = 2e-12
Identities = 41/177 (23%), Positives = 83/177 (46%), Gaps = 9/177 (5%)
Frame = +3
Query: 141 MIDSLLATYDRDSPP----DSKIVVNLTLHLRH-ANIRESESTVRIQADLQMNWIDKRLS 305
++ L Y+R P + KI + L + ++ E + L+ WID +L
Sbjct: 50 LLKDLFQDYERWVRPVEHLNDKIKIKFGLAISQLVDVDEKNQLMTTNVWLKQEWIDVKLR 109
Query: 306 WNAGEWG-CSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVSWIKRLDISTP 482
WN ++G V S+ W PD+VL + A + + + NG+V+W + +
Sbjct: 110 WNPDDYGGIKVIRVPSDSSWTPDIVLFDNADGRFEGTSTKTVIRYNGTVTWTPPANYKSS 169
Query: 483 ISMQLDNWPNDMQTCAFKFGSRMHNSDEMDFVI---DXRIYSMFESGXWDVTALSSA 644
++ + +P D+Q C+ KFGS ++ ++D ++ D F++G W++ + + +
Sbjct: 170 CTIDVTFFPFDLQNCSMKFGSWTYDGSQVDIILEDQDVDKRDFFDNGEWEIVSATGS 226
>Y08417-1|CAA69694.1| 458|Homo sapiens nicotinic acetylcholine
receptor beta3 subunit precursor protein.
Length = 458
Score = 71.3 bits (167), Expect = 4e-12
Identities = 39/137 (28%), Positives = 66/137 (48%), Gaps = 5/137 (3%)
Frame = +3
Query: 231 NIRESESTVRIQADLQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLL-NAAATTA 404
++ E + L+ W D +L WN ++G + V SE LW PD+VL NA
Sbjct: 67 DVDEKNQLMTTNVWLKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFE 126
Query: 405 GDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCAFKFGSRMHNSDEMDFV-I 581
G + V +NG+V W + +M + +P D Q C+ KFGS ++ +D + I
Sbjct: 127 GSLMTKVIVKSNGTVVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGTMVDLILI 186
Query: 582 DXRI--YSMFESGXWDV 626
+ + F++G W++
Sbjct: 187 NENVDRKDFFDNGEWEI 203
>X67513-1|CAA47851.1| 423|Homo sapiens nicotinic acetylcholine
receptor beta-3 subunit protein.
Length = 423
Score = 71.3 bits (167), Expect = 4e-12
Identities = 39/137 (28%), Positives = 66/137 (48%), Gaps = 5/137 (3%)
Frame = +3
Query: 231 NIRESESTVRIQADLQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLL-NAAATTA 404
++ E + L+ W D +L WN ++G + V SE LW PD+VL NA
Sbjct: 32 DVDEKNQLMTTNVWLKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFE 91
Query: 405 GDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCAFKFGSRMHNSDEMDFV-I 581
G + V +NG+V W + +M + +P D Q C+ KFGS ++ +D + I
Sbjct: 92 GSLMTKVIVKSNGTVVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGTMVDLILI 151
Query: 582 DXRI--YSMFESGXWDV 626
+ + F++G W++
Sbjct: 152 NENVDRKDFFDNGEWEI 168
>U62438-1|AAB40116.1| 458|Homo sapiens nicotinic acetylcholine
receptor beta3 subunit precursor protein.
Length = 458
Score = 71.3 bits (167), Expect = 4e-12
Identities = 39/137 (28%), Positives = 66/137 (48%), Gaps = 5/137 (3%)
Frame = +3
Query: 231 NIRESESTVRIQADLQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLL-NAAATTA 404
++ E + L+ W D +L WN ++G + V SE LW PD+VL NA
Sbjct: 67 DVDEKNQLMTTNVWLKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFE 126
Query: 405 GDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCAFKFGSRMHNSDEMDFV-I 581
G + V +NG+V W + +M + +P D Q C+ KFGS ++ +D + I
Sbjct: 127 GSLMTKVIVKSNGTVVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGTMVDLILI 186
Query: 582 DXRI--YSMFESGXWDV 626
+ + F++G W++
Sbjct: 187 NENVDRKDFFDNGEWEI 203
>BC069788-1|AAH69788.1| 458|Homo sapiens cholinergic receptor,
nicotinic, beta 3 protein.
Length = 458
Score = 71.3 bits (167), Expect = 4e-12
Identities = 39/137 (28%), Positives = 66/137 (48%), Gaps = 5/137 (3%)
Frame = +3
Query: 231 NIRESESTVRIQADLQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLL-NAAATTA 404
++ E + L+ W D +L WN ++G + V SE LW PD+VL NA
Sbjct: 67 DVDEKNQLMTTNVWLKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFE 126
Query: 405 GDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCAFKFGSRMHNSDEMDFV-I 581
G + V +NG+V W + +M + +P D Q C+ KFGS ++ +D + I
Sbjct: 127 GSLMTKVIVKSNGTVVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGTMVDLILI 186
Query: 582 DXRI--YSMFESGXWDV 626
+ + F++G W++
Sbjct: 187 NENVDRKDFFDNGEWEI 203
>BC069703-1|AAH69703.1| 458|Homo sapiens cholinergic receptor,
nicotinic, beta 3 protein.
Length = 458
Score = 71.3 bits (167), Expect = 4e-12
Identities = 39/137 (28%), Positives = 66/137 (48%), Gaps = 5/137 (3%)
Frame = +3
Query: 231 NIRESESTVRIQADLQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLL-NAAATTA 404
++ E + L+ W D +L WN ++G + V SE LW PD+VL NA
Sbjct: 67 DVDEKNQLMTTNVWLKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFE 126
Query: 405 GDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCAFKFGSRMHNSDEMDFV-I 581
G + V +NG+V W + +M + +P D Q C+ KFGS ++ +D + I
Sbjct: 127 GSLMTKVIVKSNGTVVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGTMVDLILI 186
Query: 582 DXRI--YSMFESGXWDV 626
+ + F++G W++
Sbjct: 187 NENVDRKDFFDNGEWEI 203
>BC069681-1|AAH69681.1| 458|Homo sapiens cholinergic receptor,
nicotinic, beta 3 protein.
Length = 458
Score = 71.3 bits (167), Expect = 4e-12
Identities = 39/137 (28%), Positives = 66/137 (48%), Gaps = 5/137 (3%)
Frame = +3
Query: 231 NIRESESTVRIQADLQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLL-NAAATTA 404
++ E + L+ W D +L WN ++G + V SE LW PD+VL NA
Sbjct: 67 DVDEKNQLMTTNVWLKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFE 126
Query: 405 GDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCAFKFGSRMHNSDEMDFV-I 581
G + V +NG+V W + +M + +P D Q C+ KFGS ++ +D + I
Sbjct: 127 GSLMTKVIVKSNGTVVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGTMVDLILI 186
Query: 582 DXRI--YSMFESGXWDV 626
+ + F++G W++
Sbjct: 187 NENVDRKDFFDNGEWEI 203
>AF140765-1|AAD33063.1| 458|Homo sapiens neuronal acetylcholine
receptor beta-3 subunit precursor protein.
Length = 458
Score = 71.3 bits (167), Expect = 4e-12
Identities = 39/137 (28%), Positives = 66/137 (48%), Gaps = 5/137 (3%)
Frame = +3
Query: 231 NIRESESTVRIQADLQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLL-NAAATTA 404
++ E + L+ W D +L WN ++G + V SE LW PD+VL NA
Sbjct: 67 DVDEKNQLMTTNVWLKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFE 126
Query: 405 GDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCAFKFGSRMHNSDEMDFV-I 581
G + V +NG+V W + +M + +P D Q C+ KFGS ++ +D + I
Sbjct: 127 GSLMTKVIVKSNGTVVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGTMVDLILI 186
Query: 582 DXRI--YSMFESGXWDV 626
+ + F++G W++
Sbjct: 187 NENVDRKDFFDNGEWEI 203
>AJ001935-1|CAA05108.1| 504|Homo sapiens CHRNB2 protein.
Length = 504
Score = 70.5 bits (165), Expect = 7e-12
Identities = 53/195 (27%), Positives = 87/195 (44%), Gaps = 7/195 (3%)
Frame = +3
Query: 72 YRFLLTCAIASAAECENATSLSLMIDSLLATYDRDSPPDSKIV-VNLTLHLRHA-NIRES 245
+ L C+ A+ E L+ S R + S++V V L + L ++ E
Sbjct: 14 FGLLRLCSGVWGADTEERLVEHLLDPSRYNKLIRPATNGSELVTVQLMVSLAQLISVHER 73
Query: 246 ESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYAL 419
E + L W D RL+W E+ + S+ +W PDVVL N A +
Sbjct: 74 EQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLPDVVLYNNADGMYEVSFYS 133
Query: 420 RARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCAFKFGSRMHNSDEMDFVIDXRIYS 599
A VS +GS+ W+ + +++ ++P D Q C KF S ++ E+D V+ + S
Sbjct: 134 NAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRSWTYDRTEIDLVLKSEVAS 193
Query: 600 MFE---SGXWDVTAL 635
+ + SG WD+ AL
Sbjct: 194 LDDFTPSGEWDIVAL 208
>Y08415-1|CAA69692.1| 502|Homo sapiens nicotinic acetylcholine
receptor beta2 subunit precursor protein.
Length = 502
Score = 70.1 bits (164), Expect = 9e-12
Identities = 44/153 (28%), Positives = 72/153 (47%), Gaps = 6/153 (3%)
Frame = +3
Query: 195 IVVNLTLHLRHA-NIRESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 368
+ V L + L ++ E E + L W D RL+W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 369 DVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCAFKFGS 545
DVVL N A + A VS +GS+ W+ + +++ ++P D Q C KF S
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRS 175
Query: 546 RMHNSDEMDFVIDXRIYSMFE---SGXWDVTAL 635
++ E+D V+ + S+ + SG WD+ AL
Sbjct: 176 WTYDRTEIDLVLKSEVASLDDFTPSGEWDIVAL 208
>X53179-1|CAA37320.1| 502|Homo sapiens precursor peptide (AA -25 to
477) protein.
Length = 502
Score = 70.1 bits (164), Expect = 9e-12
Identities = 44/153 (28%), Positives = 72/153 (47%), Gaps = 6/153 (3%)
Frame = +3
Query: 195 IVVNLTLHLRHA-NIRESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 368
+ V L + L ++ E E + L W D RL+W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 369 DVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCAFKFGS 545
DVVL N A + A VS +GS+ W+ + +++ ++P D Q C KF S
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRS 175
Query: 546 RMHNSDEMDFVIDXRIYSMFE---SGXWDVTAL 635
++ E+D V+ + S+ + SG WD+ AL
Sbjct: 176 WTYDRTEIDLVLKSEVASLDDFTPSGEWDIVAL 208
>U62437-1|AAB40115.1| 502|Homo sapiens nicotinic acetylcholine
receptor beta2 subunit precursor protein.
Length = 502
Score = 70.1 bits (164), Expect = 9e-12
Identities = 44/153 (28%), Positives = 72/153 (47%), Gaps = 6/153 (3%)
Frame = +3
Query: 195 IVVNLTLHLRHA-NIRESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 368
+ V L + L ++ E E + L W D RL+W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 369 DVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCAFKFGS 545
DVVL N A + A VS +GS+ W+ + +++ ++P D Q C KF S
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRS 175
Query: 546 RMHNSDEMDFVIDXRIYSMFE---SGXWDVTAL 635
++ E+D V+ + S+ + SG WD+ AL
Sbjct: 176 WTYDRTEIDLVLKSEVASLDDFTPSGEWDIVAL 208
>BC075041-1|AAH75041.1| 502|Homo sapiens cholinergic receptor,
nicotinic, beta 2 (neuronal) protein.
Length = 502
Score = 70.1 bits (164), Expect = 9e-12
Identities = 44/153 (28%), Positives = 72/153 (47%), Gaps = 6/153 (3%)
Frame = +3
Query: 195 IVVNLTLHLRHA-NIRESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 368
+ V L + L ++ E E + L W D RL+W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 369 DVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCAFKFGS 545
DVVL N A + A VS +GS+ W+ + +++ ++P D Q C KF S
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRS 175
Query: 546 RMHNSDEMDFVIDXRIYSMFE---SGXWDVTAL 635
++ E+D V+ + S+ + SG WD+ AL
Sbjct: 176 WTYDRTEIDLVLKSEVASLDDFTPSGEWDIVAL 208
>BC075040-1|AAH75040.1| 502|Homo sapiens cholinergic receptor,
nicotinic, beta 2 (neuronal) protein.
Length = 502
Score = 70.1 bits (164), Expect = 9e-12
Identities = 44/153 (28%), Positives = 72/153 (47%), Gaps = 6/153 (3%)
Frame = +3
Query: 195 IVVNLTLHLRHA-NIRESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 368
+ V L + L ++ E E + L W D RL+W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 369 DVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCAFKFGS 545
DVVL N A + A VS +GS+ W+ + +++ ++P D Q C KF S
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRS 175
Query: 546 RMHNSDEMDFVIDXRIYSMFE---SGXWDVTAL 635
++ E+D V+ + S+ + SG WD+ AL
Sbjct: 176 WTYDRTEIDLVLKSEVASLDDFTPSGEWDIVAL 208
>AL592078-3|CAI16184.1| 502|Homo sapiens cholinergic receptor,
nicotinic, beta 2 (neuronal) protein.
Length = 502
Score = 70.1 bits (164), Expect = 9e-12
Identities = 44/153 (28%), Positives = 72/153 (47%), Gaps = 6/153 (3%)
Frame = +3
Query: 195 IVVNLTLHLRHA-NIRESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 368
+ V L + L ++ E E + L W D RL+W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 369 DVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCAFKFGS 545
DVVL N A + A VS +GS+ W+ + +++ ++P D Q C KF S
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRS 175
Query: 546 RMHNSDEMDFVIDXRIYSMFE---SGXWDVTAL 635
++ E+D V+ + S+ + SG WD+ AL
Sbjct: 176 WTYDRTEIDLVLKSEVASLDDFTPSGEWDIVAL 208
>AF077186-1|AAD45422.1| 502|Homo sapiens neuronal nicotinic
acetylcholine receptor beta 2 protein.
Length = 502
Score = 70.1 bits (164), Expect = 9e-12
Identities = 44/153 (28%), Positives = 72/153 (47%), Gaps = 6/153 (3%)
Frame = +3
Query: 195 IVVNLTLHLRHA-NIRESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 368
+ V L + L ++ E E + L W D RL+W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 369 DVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCAFKFGS 545
DVVL N A + A VS +GS+ W+ + +++ ++P D Q C KF S
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRS 175
Query: 546 RMHNSDEMDFVIDXRIYSMFE---SGXWDVTAL 635
++ E+D V+ + S+ + SG WD+ AL
Sbjct: 176 WTYDRTEIDLVLKSEVASLDDFTPSGEWDIVAL 208
>Y16281-1|CAA76154.1| 529|Homo sapiens nicotinic acetylcholine
receptor alpha2 subunit precursor protein.
Length = 529
Score = 68.9 bits (161), Expect = 2e-11
Identities = 41/139 (29%), Positives = 69/139 (49%), Gaps = 7/139 (5%)
Frame = +3
Query: 231 NIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAA-ATTA 404
++ E + L+ W D +L WN ++G T L V SE +W PD+VL N A A
Sbjct: 97 DVDEKNQMMTTNVWLKQEWSDYKLRWNPADFGNITSLRVPSEMIWIPDIVLYNNADGEFA 156
Query: 405 GDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCAFKFGSRMHNS-----DEM 569
+ +A + + G+V W+ + S+ + +P D Q C KFGS ++ ++M
Sbjct: 157 VTHMTKAHLFSTGTVHWVPPAIYKSSCSIDVTFFPFDQQNCKMKFGSWTYDKAKIDLEQM 216
Query: 570 DFVIDXRIYSMFESGXWDV 626
+ +D + Y +ESG W +
Sbjct: 217 EQTVDLKDY--WESGEWAI 233
>U62431-1|AAB40109.1| 529|Homo sapiens nicotinic acetylcholine
receptor alpha2 subunit precursor protein.
Length = 529
Score = 68.9 bits (161), Expect = 2e-11
Identities = 41/139 (29%), Positives = 69/139 (49%), Gaps = 7/139 (5%)
Frame = +3
Query: 231 NIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAA-ATTA 404
++ E + L+ W D +L WN ++G T L V SE +W PD+VL N A A
Sbjct: 97 DVDEKNQMMTTNVWLKQEWSDYKLRWNPADFGNITSLRVPSEMIWIPDIVLYNNADGEFA 156
Query: 405 GDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCAFKFGSRMHNS-----DEM 569
+ +A + + G+V W+ + S+ + +P D Q C KFGS ++ ++M
Sbjct: 157 VTHMTKAHLFSTGTVHWVPPAIYKSSCSIDVTFFPFDQQNCKMKFGSWTYDKAKIDLEQM 216
Query: 570 DFVIDXRIYSMFESGXWDV 626
+ +D + Y +ESG W +
Sbjct: 217 EQTVDLKDY--WESGEWAI 233
>Y08418-1|CAA69695.1| 503|Homo sapiens nicotinic acetylcholine
receptor alpha3 subunit precursor protein.
Length = 503
Score = 68.5 bits (160), Expect = 3e-11
Identities = 35/123 (28%), Positives = 63/123 (51%), Gaps = 5/123 (4%)
Frame = +3
Query: 273 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 446
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 85 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 144
Query: 447 VSWIKRLDISTPISMQLDNWPNDMQTCAFKFGSRMHNSDEMDFVI---DXRIYSMFESGX 617
V+WI + + + +P D Q C KFGS ++ ++D V+ + +ESG
Sbjct: 145 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVLIGSSMNLKDYWESGE 204
Query: 618 WDV 626
W +
Sbjct: 205 WAI 207
>X53559-1|CAA37625.1| 474|Homo sapiens neuronal nicotinic
acetylcholine receptor alpha-3merase protein.
Length = 474
Score = 68.5 bits (160), Expect = 3e-11
Identities = 35/123 (28%), Positives = 63/123 (51%), Gaps = 5/123 (4%)
Frame = +3
Query: 273 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 446
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 56 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 115
Query: 447 VSWIKRLDISTPISMQLDNWPNDMQTCAFKFGSRMHNSDEMDFVI---DXRIYSMFESGX 617
V+WI + + + +P D Q C KFGS ++ ++D V+ + +ESG
Sbjct: 116 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVLIGSSMNLKDYWESGE 175
Query: 618 WDV 626
W +
Sbjct: 176 WAI 178
>U62432-1|AAB40110.1| 504|Homo sapiens nicotinic acetylcholine
receptor alpha3 subunit precursor protein.
Length = 504
Score = 68.5 bits (160), Expect = 3e-11
Identities = 35/123 (28%), Positives = 63/123 (51%), Gaps = 5/123 (4%)
Frame = +3
Query: 273 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 446
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 86 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 145
Query: 447 VSWIKRLDISTPISMQLDNWPNDMQTCAFKFGSRMHNSDEMDFVI---DXRIYSMFESGX 617
V+WI + + + +P D Q C KFGS ++ ++D V+ + +ESG
Sbjct: 146 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVLIGSSMNLKDYWESGE 205
Query: 618 WDV 626
W +
Sbjct: 206 WAI 208
>M37981-1|AAA59942.1| 503|Homo sapiens neuronal nicotinic
acetylcholine receptor protein.
Length = 503
Score = 68.5 bits (160), Expect = 3e-11
Identities = 35/123 (28%), Positives = 63/123 (51%), Gaps = 5/123 (4%)
Frame = +3
Query: 273 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 446
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 85 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 144
Query: 447 VSWIKRLDISTPISMQLDNWPNDMQTCAFKFGSRMHNSDEMDFVI---DXRIYSMFESGX 617
V+WI + + + +P D Q C KFGS ++ ++D V+ + +ESG
Sbjct: 145 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVLIGSSMNLKDYWESGE 204
Query: 618 WDV 626
W +
Sbjct: 205 WAI 207
>BT006897-1|AAP35543.1| 505|Homo sapiens cholinergic receptor,
nicotinic, alpha polypeptide 3 protein.
Length = 505
Score = 68.5 bits (160), Expect = 3e-11
Identities = 35/123 (28%), Positives = 63/123 (51%), Gaps = 5/123 (4%)
Frame = +3
Query: 273 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 446
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 87 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 146
Query: 447 VSWIKRLDISTPISMQLDNWPNDMQTCAFKFGSRMHNSDEMDFVI---DXRIYSMFESGX 617
V+WI + + + +P D Q C KFGS ++ ++D V+ + +ESG
Sbjct: 147 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVLIGSSMNLKDYWESGE 206
Query: 618 WDV 626
W +
Sbjct: 207 WAI 209
>BT006646-1|AAP35292.1| 489|Homo sapiens cholinergic receptor,
nicotinic, alpha polypeptide 3 protein.
Length = 489
Score = 68.5 bits (160), Expect = 3e-11
Identities = 35/123 (28%), Positives = 63/123 (51%), Gaps = 5/123 (4%)
Frame = +3
Query: 273 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 446
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 87 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 146
Query: 447 VSWIKRLDISTPISMQLDNWPNDMQTCAFKFGSRMHNSDEMDFVI---DXRIYSMFESGX 617
V+WI + + + +P D Q C KFGS ++ ++D V+ + +ESG
Sbjct: 147 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVLIGSSMNLKDYWESGE 206
Query: 618 WDV 626
W +
Sbjct: 207 WAI 209
>BC098443-1|AAH98443.1| 504|Homo sapiens cholinergic receptor,
nicotinic, alpha 3 protein.
Length = 504
Score = 68.5 bits (160), Expect = 3e-11
Identities = 35/123 (28%), Positives = 63/123 (51%), Gaps = 5/123 (4%)
Frame = +3
Query: 273 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 446
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 86 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 145
Query: 447 VSWIKRLDISTPISMQLDNWPNDMQTCAFKFGSRMHNSDEMDFVI---DXRIYSMFESGX 617
V+WI + + + +P D Q C KFGS ++ ++D V+ + +ESG
Sbjct: 146 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVLIGSSMNLKDYWESGE 205
Query: 618 WDV 626
W +
Sbjct: 206 WAI 208
>BC006114-1|AAH06114.1| 489|Homo sapiens CHRNA3 protein protein.
Length = 489
Score = 68.5 bits (160), Expect = 3e-11
Identities = 35/123 (28%), Positives = 63/123 (51%), Gaps = 5/123 (4%)
Frame = +3
Query: 273 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 446
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 87 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 146
Query: 447 VSWIKRLDISTPISMQLDNWPNDMQTCAFKFGSRMHNSDEMDFVI---DXRIYSMFESGX 617
V+WI + + + +P D Q C KFGS ++ ++D V+ + +ESG
Sbjct: 147 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVLIGSSMNLKDYWESGE 206
Query: 618 WDV 626
W +
Sbjct: 207 WAI 209
>BC002996-1|AAH02996.1| 505|Homo sapiens cholinergic receptor,
nicotinic, alpha 3 protein.
Length = 505
Score = 68.5 bits (160), Expect = 3e-11
Identities = 35/123 (28%), Positives = 63/123 (51%), Gaps = 5/123 (4%)
Frame = +3
Query: 273 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 446
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 87 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 146
Query: 447 VSWIKRLDISTPISMQLDNWPNDMQTCAFKFGSRMHNSDEMDFVI---DXRIYSMFESGX 617
V+WI + + + +P D Q C KFGS ++ ++D V+ + +ESG
Sbjct: 147 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVLIGSSMNLKDYWESGE 206
Query: 618 WDV 626
W +
Sbjct: 207 WAI 209
>BC001642-1|AAH01642.1| 505|Homo sapiens cholinergic receptor,
nicotinic, alpha 3 protein.
Length = 505
Score = 68.5 bits (160), Expect = 3e-11
Identities = 35/123 (28%), Positives = 63/123 (51%), Gaps = 5/123 (4%)
Frame = +3
Query: 273 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 446
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 87 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 146
Query: 447 VSWIKRLDISTPISMQLDNWPNDMQTCAFKFGSRMHNSDEMDFVI---DXRIYSMFESGX 617
V+WI + + + +P D Q C KFGS ++ ++D V+ + +ESG
Sbjct: 147 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVLIGSSMNLKDYWESGE 206
Query: 618 WDV 626
W +
Sbjct: 207 WAI 209
>BC000513-1|AAH00513.1| 505|Homo sapiens cholinergic receptor,
nicotinic, alpha 3 protein.
Length = 505
Score = 68.5 bits (160), Expect = 3e-11
Identities = 35/123 (28%), Positives = 63/123 (51%), Gaps = 5/123 (4%)
Frame = +3
Query: 273 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 446
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 87 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 146
Query: 447 VSWIKRLDISTPISMQLDNWPNDMQTCAFKFGSRMHNSDEMDFVI---DXRIYSMFESGX 617
V+WI + + + +P D Q C KFGS ++ ++D V+ + +ESG
Sbjct: 147 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVLIGSSMNLKDYWESGE 206
Query: 618 WDV 626
W +
Sbjct: 207 WAI 209
>AJ007783-1|CAA07682.1| 504|Homo sapiens nicotinic acetylcholine
receptor alpha-3 subunit protein.
Length = 504
Score = 68.5 bits (160), Expect = 3e-11
Identities = 35/123 (28%), Positives = 63/123 (51%), Gaps = 5/123 (4%)
Frame = +3
Query: 273 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 446
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 86 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 145
Query: 447 VSWIKRLDISTPISMQLDNWPNDMQTCAFKFGSRMHNSDEMDFVI---DXRIYSMFESGX 617
V+WI + + + +P D Q C KFGS ++ ++D V+ + +ESG
Sbjct: 146 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVLIGSSMNLKDYWESGE 205
Query: 618 WDV 626
W +
Sbjct: 206 WAI 208
>AF385584-1|AAK68110.1| 489|Homo sapiens nicotinic cholinergic
receptor alpha 3 protein.
Length = 489
Score = 68.5 bits (160), Expect = 3e-11
Identities = 35/123 (28%), Positives = 63/123 (51%), Gaps = 5/123 (4%)
Frame = +3
Query: 273 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 446
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 81 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 140
Query: 447 VSWIKRLDISTPISMQLDNWPNDMQTCAFKFGSRMHNSDEMDFVI---DXRIYSMFESGX 617
V+WI + + + +P D Q C KFGS ++ ++D V+ + +ESG
Sbjct: 141 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVLIGSSMNLKDYWESGE 200
Query: 618 WDV 626
W +
Sbjct: 201 WAI 203
>Y16282-1|CAA76155.1| 494|Homo sapiens nicotinic acetylcholine
receptor alpha6 subunit precursor protein.
Length = 494
Score = 68.1 bits (159), Expect = 4e-11
Identities = 46/184 (25%), Positives = 85/184 (46%), Gaps = 13/184 (7%)
Frame = +3
Query: 114 CENATSLSLMIDSLLATYDRDSPPDSKIVVNLTLHL-----RHANIRESESTVRIQADLQ 278
C + + L + Y++ P + +T+H + AN+ E + L+
Sbjct: 28 CVGCATEERLFHKLFSHYNQFIRPVENVSDPVTVHFEVAITQLANVDEVNQIMETNLWLR 87
Query: 279 MNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNG 443
W D +L W+ E+ G T V ++++W+PD+VL N A GD+ + +A + NG
Sbjct: 88 HIWNDYKLRWDPMEYDGIETLRVPADKIWKPDIVLYNNAV---GDFQVEGKTKALLKYNG 144
Query: 444 SVSWIKRLDISTPISMQLDNWPNDMQTCAFKFGSRMHNSDEMDFVIDXRIYSM---FESG 614
++W + M + +P D Q C+ KFGS ++ E+D +I M +E+
Sbjct: 145 MITWTPPAIFKSSCPMDITFFPFDHQNCSLKFGSWTYDKAEIDLLIIGSKVDMNDFWENS 204
Query: 615 XWDV 626
W++
Sbjct: 205 EWEI 208
>U62435-1|AAB40113.1| 494|Homo sapiens nicotinic acetylcholine
receptor alpha6 subunit precursor protein.
Length = 494
Score = 68.1 bits (159), Expect = 4e-11
Identities = 46/184 (25%), Positives = 85/184 (46%), Gaps = 13/184 (7%)
Frame = +3
Query: 114 CENATSLSLMIDSLLATYDRDSPPDSKIVVNLTLHL-----RHANIRESESTVRIQADLQ 278
C + + L + Y++ P + +T+H + AN+ E + L+
Sbjct: 28 CVGCATEERLFHKLFSHYNQFIRPVENVSDPVTVHFEVAITQLANVDEVNQIMETNLWLR 87
Query: 279 MNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNG 443
W D +L W+ E+ G T V ++++W+PD+VL N A GD+ + +A + NG
Sbjct: 88 HIWNDYKLRWDPMEYDGIETLRVPADKIWKPDIVLYNNAV---GDFQVEGKTKALLKYNG 144
Query: 444 SVSWIKRLDISTPISMQLDNWPNDMQTCAFKFGSRMHNSDEMDFVIDXRIYSM---FESG 614
++W + M + +P D Q C+ KFGS ++ E+D +I M +E+
Sbjct: 145 MITWTPPAIFKSSCPMDITFFPFDHQNCSLKFGSWTYDKAEIDLLIIGSKVDMNDFWENS 204
Query: 615 XWDV 626
W++
Sbjct: 205 EWEI 208
>BC014456-1|AAH14456.1| 494|Homo sapiens cholinergic receptor,
nicotinic, alpha 6 protein.
Length = 494
Score = 68.1 bits (159), Expect = 4e-11
Identities = 46/184 (25%), Positives = 85/184 (46%), Gaps = 13/184 (7%)
Frame = +3
Query: 114 CENATSLSLMIDSLLATYDRDSPPDSKIVVNLTLHL-----RHANIRESESTVRIQADLQ 278
C + + L + Y++ P + +T+H + AN+ E + L+
Sbjct: 28 CVGCATEERLFHKLFSHYNQFIRPVENVSDPVTVHFEVAITQLANVDEVNQIMETNLWLR 87
Query: 279 MNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNG 443
W D +L W+ E+ G T V ++++W+PD+VL N A GD+ + +A + NG
Sbjct: 88 HIWNDYKLRWDPMEYDGIETLRVPADKIWKPDIVLYNNAV---GDFQVEGKTKALLKYNG 144
Query: 444 SVSWIKRLDISTPISMQLDNWPNDMQTCAFKFGSRMHNSDEMDFVIDXRIYSM---FESG 614
++W + M + +P D Q C+ KFGS ++ E+D +I M +E+
Sbjct: 145 MITWTPPAIFKSSCPMDITFFPFDHQNCSLKFGSWTYDKAEIDLLIIGSKVDMNDFWENS 204
Query: 615 XWDV 626
W++
Sbjct: 205 EWEI 208
>AB079251-1|BAC06855.1| 494|Homo sapiens Nicotinic acetylcholine
receptor alpha 6 protein.
Length = 494
Score = 68.1 bits (159), Expect = 4e-11
Identities = 46/184 (25%), Positives = 85/184 (46%), Gaps = 13/184 (7%)
Frame = +3
Query: 114 CENATSLSLMIDSLLATYDRDSPPDSKIVVNLTLHL-----RHANIRESESTVRIQADLQ 278
C + + L + Y++ P + +T+H + AN+ E + L+
Sbjct: 28 CVGCATEERLFHKLFSHYNQFIRPVENVSDPVTVHFEVAITQLANVDEVNQIMETNLWLR 87
Query: 279 MNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNG 443
W D +L W+ E+ G T V ++++W+PD+VL N A GD+ + +A + NG
Sbjct: 88 HIWNDYKLRWDPMEYDGIETLRVPADKIWKPDIVLYNNAV---GDFQVEGKTKALLKYNG 144
Query: 444 SVSWIKRLDISTPISMQLDNWPNDMQTCAFKFGSRMHNSDEMDFVIDXRIYSM---FESG 614
++W + M + +P D Q C+ KFGS ++ E+D +I M +E+
Sbjct: 145 MITWTPPAIFKSSCPMDITFFPFDHQNCSLKFGSWTYDKAEIDLLIIGSKVDMNDFWENS 204
Query: 615 XWDV 626
W++
Sbjct: 205 EWEI 208
>M86383-1|AAC84176.1| 502|Homo sapiens nicotinic acetylcholine
receptor alpha 3 subunit precursor protein.
Length = 502
Score = 66.1 bits (154), Expect = 2e-10
Identities = 36/126 (28%), Positives = 65/126 (51%), Gaps = 8/126 (6%)
Frame = +3
Query: 273 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYAL----RARVSN 437
L+ W D +L WN +G + ++ V ++++W+PD+VL N A GD+ + +A +
Sbjct: 84 LKQIWNDYKLKWNPSGYGGAEFMRVPAQKIWKPDIVLYNNAV---GDFQVTTKTKALLKY 140
Query: 438 NGSVSWIKRLDISTPISMQLDNWPNDMQTCAFKFGSRMHNSDEMDFVI---DXRIYSMFE 608
G V+WI + + + +P D Q C KFGS ++ ++D V+ + +E
Sbjct: 141 TGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVLIGSSMNLKDYWE 200
Query: 609 SGXWDV 626
SG W +
Sbjct: 201 SGEWAI 206
>Y08421-1|CAA69698.1| 627|Homo sapiens nicotinic acetylcholine
receptor alpha4 subunit precursor protein.
Length = 627
Score = 64.1 bits (149), Expect = 6e-10
Identities = 48/173 (27%), Positives = 85/173 (49%), Gaps = 13/173 (7%)
Frame = +3
Query: 141 MIDSLLATYDRDSPPDSKI--VVNLTLHLRHA---NIRESESTVRIQADLQMNWIDKRLS 305
++ L + Y++ S P + I VV + L A ++ E + ++ W D +L
Sbjct: 40 LLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLR 99
Query: 306 WNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNGSVSWIKRLD 470
W+ ++ T + + SE +WRPD+VL N A GD+A+ +A + ++G V W
Sbjct: 100 WDPADYENVTSIRIPSELIWRPDIVLYNNAD---GDFAVTHLTKAHLFHDGRVQWTPPAI 156
Query: 471 ISTPISMQLDNWPNDMQTCAFKFGSRMHNSDEMDFV-IDXRI--YSMFESGXW 620
+ S+ + +P D Q C KFGS ++ ++D V + R+ +ESG W
Sbjct: 157 YKSSCSIDVTFFPFDQQNCTMKFGSWTYDKAKIDLVNMHSRVDQLDFWESGEW 209
>X89741-1|CAA61893.1| 627|Homo sapiens neuronal acetylcholine
receptor alpha-4 subunit protein.
Length = 627
Score = 64.1 bits (149), Expect = 6e-10
Identities = 48/173 (27%), Positives = 85/173 (49%), Gaps = 13/173 (7%)
Frame = +3
Query: 141 MIDSLLATYDRDSPPDSKI--VVNLTLHLRHA---NIRESESTVRIQADLQMNWIDKRLS 305
++ L + Y++ S P + I VV + L A ++ E + ++ W D +L
Sbjct: 40 LLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLR 99
Query: 306 WNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNGSVSWIKRLD 470
W+ ++ T + + SE +WRPD+VL N A GD+A+ +A + ++G V W
Sbjct: 100 WDPADYENVTSIRIPSELIWRPDIVLYNNAD---GDFAVTHLTKAHLFHDGRVQWTPPAI 156
Query: 471 ISTPISMQLDNWPNDMQTCAFKFGSRMHNSDEMDFV-IDXRI--YSMFESGXW 620
+ S+ + +P D Q C KFGS ++ ++D V + R+ +ESG W
Sbjct: 157 YKSSCSIDVTFFPFDQQNCTMKFGSWTYDKAKIDLVNMHSRVDQLDFWESGEW 209
>X87629-1|CAA60959.1| 602|Homo sapiens nicotinic acetylcholine
receptor protein.
Length = 602
Score = 64.1 bits (149), Expect = 6e-10
Identities = 48/173 (27%), Positives = 85/173 (49%), Gaps = 13/173 (7%)
Frame = +3
Query: 141 MIDSLLATYDRDSPPDSKI--VVNLTLHLRHA---NIRESESTVRIQADLQMNWIDKRLS 305
++ L + Y++ S P + I VV + L A ++ E + ++ W D +L
Sbjct: 15 LLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLR 74
Query: 306 WNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNGSVSWIKRLD 470
W+ ++ T + + SE +WRPD+VL N A GD+A+ +A + ++G V W
Sbjct: 75 WDPADYENVTSIRIPSELIWRPDIVLYNNAD---GDFAVTHLTKAHLFHDGRVQWTPPAI 131
Query: 471 ISTPISMQLDNWPNDMQTCAFKFGSRMHNSDEMDFV-IDXRI--YSMFESGXW 620
+ S+ + +P D Q C KFGS ++ ++D V + R+ +ESG W
Sbjct: 132 YKSSCSIDVTFFPFDQQNCTMKFGSWTYDKAKIDLVNMHSRVDQLDFWESGEW 184
>X66403-1|CAA47030.1| 493|Homo sapiens acetylcholine receptor
epsilon subunit CHRNE protein.
Length = 493
Score = 64.1 bits (149), Expect = 6e-10
Identities = 36/134 (26%), Positives = 71/134 (52%), Gaps = 3/134 (2%)
Frame = +3
Query: 183 PDSKIVVNLTLHLRHA-NIRESESTVRIQADLQMNWIDKRLSWNAGEWG-CSTWLVSSER 356
P+ + ++L + L + ++ E E T+ + ++W D RL+++ ++G T V SE
Sbjct: 45 PEDTVTISLKVTLTNLISLNEKEETLTTSVWIGIDWQDYRLNYSKDDFGGIETLRVPSEL 104
Query: 357 LWRPDVVLLNAAATTAG-DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCAF 533
+W P++VL N G Y V GSV+W+ + ++++ +P D Q C+
Sbjct: 105 VWLPEIVLENNIDGQFGVAYDANVLVYEGGSVTWLPPAIYRSVCAVEVTYFPFDWQNCSL 164
Query: 534 KFGSRMHNSDEMDF 575
F S+ +N++E++F
Sbjct: 165 IFRSQTYNAEEVEF 178
>U62433-1|AAB40111.1| 627|Homo sapiens nicotinic acetylcholine
receptor alpha4 subunit precursor protein.
Length = 627
Score = 64.1 bits (149), Expect = 6e-10
Identities = 48/173 (27%), Positives = 85/173 (49%), Gaps = 13/173 (7%)
Frame = +3
Query: 141 MIDSLLATYDRDSPPDSKI--VVNLTLHLRHA---NIRESESTVRIQADLQMNWIDKRLS 305
++ L + Y++ S P + I VV + L A ++ E + ++ W D +L
Sbjct: 40 LLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLR 99
Query: 306 WNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNGSVSWIKRLD 470
W+ ++ T + + SE +WRPD+VL N A GD+A+ +A + ++G V W
Sbjct: 100 WDPADYENVTSIRIPSELIWRPDIVLYNNAD---GDFAVTHLTKAHLFHDGRVQWTPPAI 156
Query: 471 ISTPISMQLDNWPNDMQTCAFKFGSRMHNSDEMDFV-IDXRI--YSMFESGXW 620
+ S+ + +P D Q C KFGS ++ ++D V + R+ +ESG W
Sbjct: 157 YKSSCSIDVTFFPFDQQNCTMKFGSWTYDKAKIDLVNMHSRVDQLDFWESGEW 209
>L35901-1|AAA64743.1| 627|Homo sapiens nicotinic acetylcholine
receptor alpha 4 subunit protein.
Length = 627
Score = 64.1 bits (149), Expect = 6e-10
Identities = 48/173 (27%), Positives = 85/173 (49%), Gaps = 13/173 (7%)
Frame = +3
Query: 141 MIDSLLATYDRDSPPDSKI--VVNLTLHLRHA---NIRESESTVRIQADLQMNWIDKRLS 305
++ L + Y++ S P + I VV + L A ++ E + ++ W D +L
Sbjct: 40 LLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLR 99
Query: 306 WNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNGSVSWIKRLD 470
W+ ++ T + + SE +WRPD+VL N A GD+A+ +A + ++G V W
Sbjct: 100 WDPADYENVTSIRIPSELIWRPDIVLYNNAD---GDFAVTHLTKAHLFHDGRVQWTPPAI 156
Query: 471 ISTPISMQLDNWPNDMQTCAFKFGSRMHNSDEMDFV-IDXRI--YSMFESGXW 620
+ S+ + +P D Q C KFGS ++ ++D V + R+ +ESG W
Sbjct: 157 YKSSCSIDVTFFPFDQQNCTMKFGSWTYDKAKIDLVNMHSRVDQLDFWESGEW 209
>DQ093071-1|AAY88737.1| 627|Homo sapiens cholinergic receptor,
nicotinic, alpha polypeptide 4 protein.
Length = 627
Score = 64.1 bits (149), Expect = 6e-10
Identities = 48/173 (27%), Positives = 85/173 (49%), Gaps = 13/173 (7%)
Frame = +3
Query: 141 MIDSLLATYDRDSPPDSKI--VVNLTLHLRHA---NIRESESTVRIQADLQMNWIDKRLS 305
++ L + Y++ S P + I VV + L A ++ E + ++ W D +L
Sbjct: 40 LLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLR 99
Query: 306 WNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNGSVSWIKRLD 470
W+ ++ T + + SE +WRPD+VL N A GD+A+ +A + ++G V W
Sbjct: 100 WDPADYENVTSIRIPSELIWRPDIVLYNNAD---GDFAVTHLTKAHLFHDGRVQWTPPAI 156
Query: 471 ISTPISMQLDNWPNDMQTCAFKFGSRMHNSDEMDFV-IDXRI--YSMFESGXW 620
+ S+ + +P D Q C KFGS ++ ++D V + R+ +ESG W
Sbjct: 157 YKSSCSIDVTFFPFDQQNCTMKFGSWTYDKAKIDLVNMHSRVDQLDFWESGEW 209
>BC096290-1|AAH96290.1| 627|Homo sapiens cholinergic receptor,
nicotinic, alpha 4 protein.
Length = 627
Score = 64.1 bits (149), Expect = 6e-10
Identities = 48/173 (27%), Positives = 85/173 (49%), Gaps = 13/173 (7%)
Frame = +3
Query: 141 MIDSLLATYDRDSPPDSKI--VVNLTLHLRHA---NIRESESTVRIQADLQMNWIDKRLS 305
++ L + Y++ S P + I VV + L A ++ E + ++ W D +L
Sbjct: 40 LLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLR 99
Query: 306 WNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNGSVSWIKRLD 470
W+ ++ T + + SE +WRPD+VL N A GD+A+ +A + ++G V W
Sbjct: 100 WDPADYENVTSIRIPSELIWRPDIVLYNNAD---GDFAVTHLTKAHLFHDGRVQWTPPAI 156
Query: 471 ISTPISMQLDNWPNDMQTCAFKFGSRMHNSDEMDFV-IDXRI--YSMFESGXW 620
+ S+ + +P D Q C KFGS ++ ++D V + R+ +ESG W
Sbjct: 157 YKSSCSIDVTFFPFDQQNCTMKFGSWTYDKAKIDLVNMHSRVDQLDFWESGEW 209
>AF105999-1|AAD24503.1| 493|Homo sapiens acetylcholine receptor
epsilon subunit protein.
Length = 493
Score = 64.1 bits (149), Expect = 6e-10
Identities = 36/134 (26%), Positives = 71/134 (52%), Gaps = 3/134 (2%)
Frame = +3
Query: 183 PDSKIVVNLTLHLRHA-NIRESESTVRIQADLQMNWIDKRLSWNAGEWG-CSTWLVSSER 356
P+ + ++L + L + ++ E E T+ + ++W D RL+++ ++G T V SE
Sbjct: 45 PEDTVTISLKVTLTNLISLNEKEETLTTSVWIGIDWQDYRLNYSKDDFGGIETLRVPSEL 104
Query: 357 LWRPDVVLLNAAATTAG-DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCAF 533
+W P++VL N G Y V GSV+W+ + ++++ +P D Q C+
Sbjct: 105 VWLPEIVLENNIDGQFGVAYDANVLVYEGGSVTWLPPAIYRSVCAVEVTYFPFDWQNCSL 164
Query: 534 KFGSRMHNSDEMDF 575
F S+ +N++E++F
Sbjct: 165 IFRSQTYNAEEVEF 178
>X14830-1|CAA32939.1| 501|Homo sapiens protein ( Human mRNA for
muscle acetylcholine receptor beta-subunit. ).
Length = 501
Score = 62.5 bits (145), Expect = 2e-09
Identities = 44/130 (33%), Positives = 67/130 (51%), Gaps = 4/130 (3%)
Frame = +3
Query: 192 KIVVNLTL-HLRHANIRESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWR 365
++ V L L L N ++ E + ++ DL+ W D RLSW+ E G + +++E +W
Sbjct: 53 RVSVGLILAQLISLNEKDEEMSTKVYLDLE--WTDYRLSWDPAEHDGIDSLRITAESVWL 110
Query: 366 PDVVLLNAAATTAGDYAL--RARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCAFKF 539
PDVVLLN D AL VS++GSV W + S+Q+ +P D Q C F
Sbjct: 111 PDVVLLNNNDGNF-DVALDISVVVSSDGSVRWQPPGIYRSSCSIQVTYFPFDWQNCTMVF 169
Query: 540 GSRMHNSDEM 569
S ++S E+
Sbjct: 170 SSYSYDSSEV 179
>BC011371-1|AAH11371.1| 501|Homo sapiens cholinergic receptor,
nicotinic, beta 1 (muscle) protein.
Length = 501
Score = 62.5 bits (145), Expect = 2e-09
Identities = 44/130 (33%), Positives = 67/130 (51%), Gaps = 4/130 (3%)
Frame = +3
Query: 192 KIVVNLTL-HLRHANIRESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWR 365
++ V L L L N ++ E + ++ DL+ W D RLSW+ E G + +++E +W
Sbjct: 53 RVSVGLILAQLISLNEKDEEMSTKVYLDLE--WTDYRLSWDPAEHDGIDSLRITAESVWL 110
Query: 366 PDVVLLNAAATTAGDYAL--RARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCAFKF 539
PDVVLLN D AL VS++GSV W + S+Q+ +P D Q C F
Sbjct: 111 PDVVLLNNNDGNF-DVALDISVVVSSDGSVRWQPPGIYRSSCSIQVTYFPFDWQNCTMVF 169
Query: 540 GSRMHNSDEM 569
S ++S E+
Sbjct: 170 SSYSYDSSEV 179
>X01715-1|CAA25861.1| 520|Homo sapiens acetylcholine receptor gamma
chain precursor protein.
Length = 520
Score = 62.1 bits (144), Expect = 3e-09
Identities = 43/152 (28%), Positives = 74/152 (48%), Gaps = 8/152 (5%)
Frame = +3
Query: 141 MIDSLLATYDRDSPPDSKI--VVNLTLHLRHANI---RESESTVRIQADLQMNWIDKRLS 305
++ L+ YD + P + VVN++L L N+ E E + ++M W D RL
Sbjct: 32 LLADLMQNYDPNLRPAERDSDVVNVSLKLTLTNLISLNEREEALTTNVWIEMQWCDYRLR 91
Query: 306 WNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARV--SNNGSVSWIKRLDIS 476
W+ ++ G V S +WRPD+VL N + AL V S +G + W+
Sbjct: 92 WDPRDYEGLWVLRVPSTMVWRPDIVLENNVDGVF-EVALYCNVLVSPDGCIYWLPPAIFR 150
Query: 477 TPISMQLDNWPNDMQTCAFKFGSRMHNSDEMD 572
+ S+ + +P D Q C+ F S+ ++++E+D
Sbjct: 151 SACSISVTYFPFDWQNCSLIFQSQTYSTNEID 182
>AC092165-3|AAY24103.1| 520|Homo sapiens unknown protein.
Length = 520
Score = 62.1 bits (144), Expect = 3e-09
Identities = 43/152 (28%), Positives = 74/152 (48%), Gaps = 8/152 (5%)
Frame = +3
Query: 141 MIDSLLATYDRDSPPDSKI--VVNLTLHLRHANI---RESESTVRIQADLQMNWIDKRLS 305
++ L+ YD + P + VVN++L L N+ E E + ++M W D RL
Sbjct: 32 LLADLMQNYDPNLRPAERDSDVVNVSLKLTLTNLISLNEREEALTTNVWIEMQWCDYRLR 91
Query: 306 WNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARV--SNNGSVSWIKRLDIS 476
W+ ++ G V S +WRPD+VL N + AL V S +G + W+
Sbjct: 92 WDPRDYEGLWVLRVPSTMVWRPDIVLENNVDGVF-EVALYCNVLVSPDGCIYWLPPAIFR 150
Query: 477 TPISMQLDNWPNDMQTCAFKFGSRMHNSDEMD 572
+ S+ + +P D Q C+ F S+ ++++E+D
Sbjct: 151 SACSISVTYFPFDWQNCSLIFQSQTYSTNEID 182
>BC023553-1|AAH23553.1| 501|Homo sapiens cholinergic receptor,
nicotinic, beta 1 (muscle) protein.
Length = 501
Score = 61.3 bits (142), Expect = 4e-09
Identities = 42/132 (31%), Positives = 68/132 (51%), Gaps = 6/132 (4%)
Frame = +3
Query: 192 KIVVNLTL-HLRHANIRESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWR 365
++ V L L L N ++ E + ++ DL+ W D RLSW+ E G + +++E +W
Sbjct: 53 RVSVGLILAQLISLNEKDEEMSTKVYLDLE--WTDYRLSWDPAEHDGIDSLRITAESVWL 110
Query: 366 PDVVLLNAAATTAGDY----ALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCAF 533
PDVVLLN G++ + VS++GSV W + S+Q+ +P D Q C
Sbjct: 111 PDVVLLN---NNDGNFYVALDISVVVSSDGSVRWQPPGIYRSSCSIQVTYFPFDWQNCTM 167
Query: 534 KFGSRMHNSDEM 569
F S ++S E+
Sbjct: 168 VFSSYSYDSSEV 179
>DQ644022-1|ABG35128.1| 456|Homo sapiens 5-HT3 receptor subunit E
splice variant HTR3Ea protein.
Length = 456
Score = 60.9 bits (141), Expect = 6e-09
Identities = 34/147 (23%), Positives = 68/147 (46%), Gaps = 9/147 (6%)
Frame = +3
Query: 273 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 449
L+M W + +SWN E G + ++++ LW PD+ ++ L A VSN G +
Sbjct: 91 LEMVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEGRI 150
Query: 450 SWIKRLDISTPISMQLDNWPNDMQTCAFKFGSRMHNSDEMDFVIDXRIYSMFES------ 611
+ K + + + ++ + +P D Q C F S ++ D M ++ ++ + ++
Sbjct: 151 RYKKPMKVDSICNLDIFYFPFDQQNCTLTFSSFLYTVDSMLLDMEKEVWEITDASRNILQ 210
Query: 612 --GXWDVTALSSAVXSPGTGGEVXARV 686
G W++ LS A GG + ++
Sbjct: 211 THGEWELLGLSKATAKLSRGGNLYDQI 237
>BC101183-1|AAI01184.1| 471|Homo sapiens 5-hydroxytryptamine
(serotonin) receptor 3, family member E protein.
Length = 471
Score = 60.9 bits (141), Expect = 6e-09
Identities = 34/147 (23%), Positives = 68/147 (46%), Gaps = 9/147 (6%)
Frame = +3
Query: 273 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 449
L+M W + +SWN E G + ++++ LW PD+ ++ L A VSN G +
Sbjct: 106 LEMVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEGRI 165
Query: 450 SWIKRLDISTPISMQLDNWPNDMQTCAFKFGSRMHNSDEMDFVIDXRIYSMFES------ 611
+ K + + + ++ + +P D Q C F S ++ D M ++ ++ + ++
Sbjct: 166 RYKKPMKVDSICNLDIFYFPFDQQNCTLTFSSFLYTVDSMLLDMEKEVWEITDASRNILQ 225
Query: 612 --GXWDVTALSSAVXSPGTGGEVXARV 686
G W++ LS A GG + ++
Sbjct: 226 THGEWELLGLSKATAKLSRGGNLYDQI 252
>BC101182-1|AAI01183.1| 471|Homo sapiens 5-hydroxytryptamine
(serotonin) receptor 3, family member E protein.
Length = 471
Score = 60.9 bits (141), Expect = 6e-09
Identities = 34/147 (23%), Positives = 68/147 (46%), Gaps = 9/147 (6%)
Frame = +3
Query: 273 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 449
L+M W + +SWN E G + ++++ LW PD+ ++ L A VSN G +
Sbjct: 106 LEMVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEGRI 165
Query: 450 SWIKRLDISTPISMQLDNWPNDMQTCAFKFGSRMHNSDEMDFVIDXRIYSMFES------ 611
+ K + + + ++ + +P D Q C F S ++ D M ++ ++ + ++
Sbjct: 166 RYKKPMKVDSICNLDIFYFPFDQQNCTLTFSSFLYTVDSMLLDMEKEVWEITDASRNILQ 225
Query: 612 --GXWDVTALSSAVXSPGTGGEVXARV 686
G W++ LS A GG + ++
Sbjct: 226 THGEWELLGLSKATAKLSRGGNLYDQI 252
>AY159813-1|AAO38167.2| 471|Homo sapiens 5-hydroxytryptamine
serotonin receptor 3E protein.
Length = 471
Score = 60.9 bits (141), Expect = 6e-09
Identities = 34/147 (23%), Positives = 68/147 (46%), Gaps = 9/147 (6%)
Frame = +3
Query: 273 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 449
L+M W + +SWN E G + ++++ LW PD+ ++ L A VSN G +
Sbjct: 106 LEMVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEGRI 165
Query: 450 SWIKRLDISTPISMQLDNWPNDMQTCAFKFGSRMHNSDEMDFVIDXRIYSMFES------ 611
+ K + + + ++ + +P D Q C F S ++ D M ++ ++ + ++
Sbjct: 166 RYKKPMKVDSICNLDIFYFPFDQQNCTLTFSSFLYTVDSMLLDMEKEVWEITDASRNILQ 225
Query: 612 --GXWDVTALSSAVXSPGTGGEVXARV 686
G W++ LS A GG + ++
Sbjct: 226 THGEWELLGLSKATAKLSRGGNLYDQI 252
>Y00762-1|CAA68731.1| 457|Homo sapiens protein ( Human mRNA for
muscle acetylcholine receptor alpha-subunit. ).
Length = 457
Score = 59.7 bits (138), Expect = 1e-08
Identities = 43/165 (26%), Positives = 76/165 (46%), Gaps = 10/165 (6%)
Frame = +3
Query: 81 LLTCAIASAAECENATSLSLMIDSLLATYDRDSPP--DSKIVVNLTLHLRHA---NIRES 245
LL ++ SA + + ++ L Y P D + VV +T+ L+ N+ E
Sbjct: 7 LLLFSLCSAGLVLGSEHETRLVAKLFKDYSSVVRPVEDHRQVVEVTVGLQLIQLINVDEV 66
Query: 246 ESTVRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYAL- 419
V L+ W+D L WN ++G + + SE++WRPD+VL N A GD+A+
Sbjct: 67 NQIVTTNVRLKQQWVDYNLKWNPDDYGGVKKIHIPSEKIWRPDLVLYNNA---DGDFAIV 123
Query: 420 ---RARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCAFKFGS 545
+ + G ++W + + + ++P D Q C+ K G+
Sbjct: 124 KFTKVLLQYTGHITWTPPAIFKSYCEIIVTHFPFDEQNCSMKLGT 168
>X02502-1|CAA26344.1| 457|Homo sapiens acetylcholine receptor
protein.
Length = 457
Score = 59.7 bits (138), Expect = 1e-08
Identities = 43/165 (26%), Positives = 76/165 (46%), Gaps = 10/165 (6%)
Frame = +3
Query: 81 LLTCAIASAAECENATSLSLMIDSLLATYDRDSPP--DSKIVVNLTLHLRHA---NIRES 245
LL ++ SA + + ++ L Y P D + VV +T+ L+ N+ E
Sbjct: 7 LLLFSLCSAGLVLGSEHETRLVAKLFKDYSSVVRPVEDHRQVVEVTVGLQLIQLINVDEV 66
Query: 246 ESTVRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYAL- 419
V L+ W+D L WN ++G + + SE++WRPD+VL N A GD+A+
Sbjct: 67 NQIVTTNVRLKQQWVDYNLKWNPDDYGGVKKIHIPSEKIWRPDLVLYNNA---DGDFAIV 123
Query: 420 ---RARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCAFKFGS 545
+ + G ++W + + + ++P D Q C+ K G+
Sbjct: 124 KFTKVLLQYTGHITWTPPAIFKSYCEIIVTHFPFDEQNCSMKLGT 168
>S77094-1|AAD14247.1| 457|Homo sapiens nicotinic acetylcholine
receptor alpha subunit|AChR protein.
Length = 457
Score = 59.7 bits (138), Expect = 1e-08
Identities = 43/165 (26%), Positives = 76/165 (46%), Gaps = 10/165 (6%)
Frame = +3
Query: 81 LLTCAIASAAECENATSLSLMIDSLLATYDRDSPP--DSKIVVNLTLHLRHA---NIRES 245
LL ++ SA + + ++ L Y P D + VV +T+ L+ N+ E
Sbjct: 7 LLLFSLCSAGLVLGSEHETRLVAKLFKDYSSVVRPVEDHRQVVEVTVGLQLIQLINVDEV 66
Query: 246 ESTVRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYAL- 419
V L+ W+D L WN ++G + + SE++WRPD+VL N A GD+A+
Sbjct: 67 NQIVTTNVRLKQQWVDYNLKWNPDDYGGVKKIHIPSEKIWRPDLVLYNNA---DGDFAIV 123
Query: 420 ---RARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCAFKFGS 545
+ + G ++W + + + ++P D Q C+ K G+
Sbjct: 124 KFTKVLLQYTGHITWTPPAIFKSYCEIIVTHFPFDEQNCSMKLGT 168
>BC006314-1|AAH06314.1| 269|Homo sapiens CHRNA1 protein protein.
Length = 269
Score = 59.7 bits (138), Expect = 1e-08
Identities = 43/165 (26%), Positives = 76/165 (46%), Gaps = 10/165 (6%)
Frame = +3
Query: 81 LLTCAIASAAECENATSLSLMIDSLLATYDRDSPP--DSKIVVNLTLHLRHA---NIRES 245
LL ++ SA + + ++ L Y P D + VV +T+ L+ N+ E
Sbjct: 7 LLLFSLCSAGLVLGSEHETRLVAKLFKDYSSVVRPVEDHRQVVEVTVGLQLIQLINVDEV 66
Query: 246 ESTVRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYAL- 419
V L+ W+D L WN ++G + + SE++WRPD+VL N A GD+A+
Sbjct: 67 NQIVTTNVRLKQQWVDYNLKWNPDDYGGVKKIHIPSEKIWRPDLVLYNNA---DGDFAIV 123
Query: 420 ---RARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCAFKFGS 545
+ + G ++W + + + ++P D Q C+ K G+
Sbjct: 124 KFTKVLLQYTGHITWTPPAIFKSYCEIIVTHFPFDEQNCSMKLGT 168
>AC018890-1|AAY14687.1| 457|Homo sapiens unknown protein.
Length = 457
Score = 59.7 bits (138), Expect = 1e-08
Identities = 43/165 (26%), Positives = 76/165 (46%), Gaps = 10/165 (6%)
Frame = +3
Query: 81 LLTCAIASAAECENATSLSLMIDSLLATYDRDSPP--DSKIVVNLTLHLRHA---NIRES 245
LL ++ SA + + ++ L Y P D + VV +T+ L+ N+ E
Sbjct: 7 LLLFSLCSAGLVLGSEHETRLVAKLFKDYSSVVRPVEDHRQVVEVTVGLQLIQLINVDEV 66
Query: 246 ESTVRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYAL- 419
V L+ W+D L WN ++G + + SE++WRPD+VL N A GD+A+
Sbjct: 67 NQIVTTNVRLKQQWVDYNLKWNPDDYGGVKKIHIPSEKIWRPDLVLYNNA---DGDFAIV 123
Query: 420 ---RARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCAFKFGS 545
+ + G ++W + + + ++P D Q C+ K G+
Sbjct: 124 KFTKVLLQYTGHITWTPPAIFKSYCEIIVTHFPFDEQNCSMKLGT 168
>AY349353-1|AAQ93477.1| 456|Homo sapiens 5-HT3c1 serotonin
receptor-like protein protein.
Length = 456
Score = 59.3 bits (137), Expect = 2e-08
Identities = 34/151 (22%), Positives = 69/151 (45%), Gaps = 9/151 (5%)
Frame = +3
Query: 261 IQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSN 437
+ A L + W + +SWN E G + ++++ LW PD+ ++ L A VSN
Sbjct: 87 MSAILDVVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSN 146
Query: 438 NGSVSWIKRLDISTPISMQLDNWPNDMQTCAFKFGSRMHNSDEMDFVIDXRIYSMFES-- 611
G + + K + + + ++ + +P D Q C F S ++ D M ++ ++ + ++
Sbjct: 147 EGRIRYKKPMKVDSICNLDIFYFPFDQQNCTLTFSSFLYTVDSMLLDMEKEVWEITDASR 206
Query: 612 ------GXWDVTALSSAVXSPGTGGEVXARV 686
G W++ LS A GG + ++
Sbjct: 207 NILQTHGEWELLGLSKATAKLSRGGNLYDQI 237
>AY349352-1|AAQ93476.1| 441|Homo sapiens 5-HT3c1 serotonin
receptor-like protein protein.
Length = 441
Score = 59.3 bits (137), Expect = 2e-08
Identities = 34/151 (22%), Positives = 69/151 (45%), Gaps = 9/151 (5%)
Frame = +3
Query: 261 IQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSN 437
+ A L + W + +SWN E G + ++++ LW PD+ ++ L A VSN
Sbjct: 72 MSAILDVVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSN 131
Query: 438 NGSVSWIKRLDISTPISMQLDNWPNDMQTCAFKFGSRMHNSDEMDFVIDXRIYSMFES-- 611
G + + K + + + ++ + +P D Q C F S ++ D M ++ ++ + ++
Sbjct: 132 EGRIRYKKPMKVDSICNLDIFYFPFDQQNCTLTFSSFLYTVDSMLLDMEKEVWEITDASR 191
Query: 612 ------GXWDVTALSSAVXSPGTGGEVXARV 686
G W++ LS A GG + ++
Sbjct: 192 NILQTHGEWELLGLSKATAKLSRGGNLYDQI 222
>Z23141-1|CAA80672.1| 479|Homo sapiens cholinergic receptor,
nicotinic, alpha polypeptide 7 protein.
Length = 479
Score = 58.0 bits (134), Expect = 4e-08
Identities = 39/157 (24%), Positives = 73/157 (46%), Gaps = 3/157 (1%)
Frame = +3
Query: 174 DSPPDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSS 350
DS P + + +L+L L+ ++ E + LQM+W D L WN E+ G T
Sbjct: 24 DSQPLT-VYFSLSL-LQIMDVDEKNQVLTTNIWLQMSWTDHYLQWNVSEYPGVKTVRFPD 81
Query: 351 ERLWRPDVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTC 527
++W+PD++L N+A + V+++G ++ + + + +P D+Q C
Sbjct: 82 GQIWKPDILLYNSADERFDATFHTNVLVNSSGHCQYLPPGIFKSSCYIDVRWFPFDVQHC 141
Query: 528 AFKFGSRMHNSDEMDFVI-DXRIYSMFESGXWDVTAL 635
KFGS + +D + + I +G WD+ +
Sbjct: 142 KLKFGSWSYGGWSLDLQMQEADISGYIPNGEWDLVGI 178
>Y08420-1|CAA69697.1| 502|Homo sapiens nicotinic acetylcholine
receptor alpha7 subunit precursor protein.
Length = 502
Score = 58.0 bits (134), Expect = 4e-08
Identities = 39/157 (24%), Positives = 73/157 (46%), Gaps = 3/157 (1%)
Frame = +3
Query: 174 DSPPDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSS 350
DS P + + +L+L L+ ++ E + LQM+W D L WN E+ G T
Sbjct: 47 DSQPLT-VYFSLSL-LQIMDVDEKNQVLTTNIWLQMSWTDHYLQWNVSEYPGVKTVRFPD 104
Query: 351 ERLWRPDVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTC 527
++W+PD++L N+A + V+++G ++ + + + +P D+Q C
Sbjct: 105 GQIWKPDILLYNSADERFDATFHTNVLVNSSGHCQYLPPGIFKSSCYIDVRWFPFDVQHC 164
Query: 528 AFKFGSRMHNSDEMDFVI-DXRIYSMFESGXWDVTAL 635
KFGS + +D + + I +G WD+ +
Sbjct: 165 KLKFGSWSYGGWSLDLQMQEADISGYIPNGEWDLVGI 201
>X70297-1|CAA49778.1| 502|Homo sapiens neuronal nicotinic
acetylocholine receptor alpha-7 subunit protein.
Length = 502
Score = 58.0 bits (134), Expect = 4e-08
Identities = 39/157 (24%), Positives = 73/157 (46%), Gaps = 3/157 (1%)
Frame = +3
Query: 174 DSPPDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSS 350
DS P + + +L+L L+ ++ E + LQM+W D L WN E+ G T
Sbjct: 47 DSQPLT-VYFSLSL-LQIMDVDEKNQVLTTNIWLQMSWTDHYLQWNVSEYPGVKTVRFPD 104
Query: 351 ERLWRPDVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTC 527
++W+PD++L N+A + V+++G ++ + + + +P D+Q C
Sbjct: 105 GQIWKPDILLYNSADERFDATFHTNVLVNSSGHCQYLPPGIFKSSCYIDVRWFPFDVQHC 164
Query: 528 AFKFGSRMHNSDEMDFVI-DXRIYSMFESGXWDVTAL 635
KFGS + +D + + I +G WD+ +
Sbjct: 165 KLKFGSWSYGGWSLDLQMQEADISGYIPNGEWDLVGI 201
>U62436-1|AAB40114.1| 502|Homo sapiens nicotinic acetylcholine
receptor alpha7 subunit precursor protein.
Length = 502
Score = 58.0 bits (134), Expect = 4e-08
Identities = 39/157 (24%), Positives = 73/157 (46%), Gaps = 3/157 (1%)
Frame = +3
Query: 174 DSPPDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSS 350
DS P + + +L+L L+ ++ E + LQM+W D L WN E+ G T
Sbjct: 47 DSQPLT-VYFSLSL-LQIMDVDEKNQVLTTNIWLQMSWTDHYLQWNVSEYPGVKTVRFPD 104
Query: 351 ERLWRPDVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTC 527
++W+PD++L N+A + V+++G ++ + + + +P D+Q C
Sbjct: 105 GQIWKPDILLYNSADERFDATFHTNVLVNSSGHCQYLPPGIFKSSCYIDVRWFPFDVQHC 164
Query: 528 AFKFGSRMHNSDEMDFVI-DXRIYSMFESGXWDVTAL 635
KFGS + +D + + I +G WD+ +
Sbjct: 165 KLKFGSWSYGGWSLDLQMQEADISGYIPNGEWDLVGI 201
>AJ586911-1|CAE52911.1| 502|Homo sapiens nicotinic acetylcholine
alpha-7 subunit protein.
Length = 502
Score = 58.0 bits (134), Expect = 4e-08
Identities = 39/157 (24%), Positives = 73/157 (46%), Gaps = 3/157 (1%)
Frame = +3
Query: 174 DSPPDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSS 350
DS P + + +L+L L+ ++ E + LQM+W D L WN E+ G T
Sbjct: 47 DSQPLT-VYFSLSL-LQIMDVDEKNQVLTTNIWLQMSWTDHYLQWNVSEYPGVKTVRFPD 104
Query: 351 ERLWRPDVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTC 527
++W+PD++L N+A + V+++G ++ + + + +P D+Q C
Sbjct: 105 GQIWKPDILLYNSADERFDATFHTNVLVNSSGHCQYLPPGIFKSSCYIDVRWFPFDVQHC 164
Query: 528 AFKFGSRMHNSDEMDFVI-DXRIYSMFESGXWDVTAL 635
KFGS + +D + + I +G WD+ +
Sbjct: 165 KLKFGSWSYGGWSLDLQMQEADISGYIPNGEWDLVGI 201
>AJ295237-1|CAC16144.1| 450|Homo sapiens neuronal nicotinic
acetylcholine receptor subunit4 protein.
Length = 450
Score = 58.0 bits (134), Expect = 4e-08
Identities = 45/165 (27%), Positives = 71/165 (43%), Gaps = 10/165 (6%)
Frame = +3
Query: 108 AEC---ENATSLSLMIDSLLATYDRDSPP--DSKIVVNLTLHLRHANI---RESESTVRI 263
AEC E +L L D L A Y P D+ +N+TL + + I E + +
Sbjct: 20 AECLGAEGRLALKLFRD-LFANYTSALRPVADTDQTLNVTLEVTLSQIIDMDERNQVLTL 78
Query: 264 QADLQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSN 437
++ W D L W+ +G + S +WRPD+VL N A A G + + +
Sbjct: 79 YLWIRQEWTDAYLRWDPNAYGGLDAIRIPSSLVWRPDIVLYNKADAQPPGSASTNVVLRH 138
Query: 438 NGSVSWIKRLDISTPISMQLDNWPNDMQTCAFKFGSRMHNSDEMD 572
+G+V W + + + +P D Q C FGS H ++D
Sbjct: 139 DGAVRWDAPAITRSSCRVDVAAFPFDAQHCGLTFGSWTHGGHQLD 183
>AJ278118-1|CAC20435.1| 450|Homo sapiens neuronal nicotinic
acetylcholine alpha10 subunit protein.
Length = 450
Score = 58.0 bits (134), Expect = 4e-08
Identities = 45/165 (27%), Positives = 71/165 (43%), Gaps = 10/165 (6%)
Frame = +3
Query: 108 AEC---ENATSLSLMIDSLLATYDRDSPP--DSKIVVNLTLHLRHANI---RESESTVRI 263
AEC E +L L D L A Y P D+ +N+TL + + I E + +
Sbjct: 20 AECLGAEGRLALKLFRD-LFANYTSALRPVADTDQTLNVTLEVTLSQIIDMDERNQVLTL 78
Query: 264 QADLQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSN 437
++ W D L W+ +G + S +WRPD+VL N A A G + + +
Sbjct: 79 YLWIRQEWTDAYLRWDPNAYGGLDAIRIPSSLVWRPDIVLYNKADAQPPGSASTNVVLRH 138
Query: 438 NGSVSWIKRLDISTPISMQLDNWPNDMQTCAFKFGSRMHNSDEMD 572
+G+V W + + + +P D Q C FGS H ++D
Sbjct: 139 DGAVRWDAPAITRSSCRVDVAAFPFDAQHCGLTFGSWTHGGHQLD 183
>AF327367-1|AAK14333.1| 450|Homo sapiens nicotinic acetylcholine
receptor subunit alpha 10 protein.
Length = 450
Score = 58.0 bits (134), Expect = 4e-08
Identities = 45/165 (27%), Positives = 71/165 (43%), Gaps = 10/165 (6%)
Frame = +3
Query: 108 AEC---ENATSLSLMIDSLLATYDRDSPP--DSKIVVNLTLHLRHANI---RESESTVRI 263
AEC E +L L D L A Y P D+ +N+TL + + I E + +
Sbjct: 20 AECLGAEGRLALKLFRD-LFANYTSALRPVADTDQTLNVTLEVTLSQIIDMDERNQVLTL 78
Query: 264 QADLQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSN 437
++ W D L W+ +G + S +WRPD+VL N A A G + + +
Sbjct: 79 YLWIRQEWTDAYLRWDPNAYGGLDAIRIPSSLVWRPDIVLYNKADAQPPGSASTNVVLRH 138
Query: 438 NGSVSWIKRLDISTPISMQLDNWPNDMQTCAFKFGSRMHNSDEMD 572
+G+V W + + + +P D Q C FGS H ++D
Sbjct: 139 DGAVRWDAPAITRSSCRVDVAAFPFDAQHCGLTFGSWTHGGHQLD 183
>AF199235-1|AAG00795.2| 450|Homo sapiens nicotinic acetylcholine
receptor subunit alpha 10 protein.
Length = 450
Score = 58.0 bits (134), Expect = 4e-08
Identities = 45/165 (27%), Positives = 71/165 (43%), Gaps = 10/165 (6%)
Frame = +3
Query: 108 AEC---ENATSLSLMIDSLLATYDRDSPP--DSKIVVNLTLHLRHANI---RESESTVRI 263
AEC E +L L D L A Y P D+ +N+TL + + I E + +
Sbjct: 20 AECLGAEGRLALKLFRD-LFANYTSALRPVADTDQTLNVTLEVTLSQIIDMDERNQVLTL 78
Query: 264 QADLQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSN 437
++ W D L W+ +G + S +WRPD+VL N A A G + + +
Sbjct: 79 YLWIRQEWTDAYLRWDPNAYGGLDAIRIPSSLVWRPDIVLYNKADAQPPGSASTNVVLRH 138
Query: 438 NGSVSWIKRLDISTPISMQLDNWPNDMQTCAFKFGSRMHNSDEMD 572
+G+V W + + + +P D Q C FGS H ++D
Sbjct: 139 DGAVRWDAPAITRSSCRVDVAAFPFDAQHCGLTFGSWTHGGHQLD 183
>BC113575-1|AAI13576.1| 479|Homo sapiens cholinergic receptor,
nicotinic, alpha 9 protein.
Length = 479
Score = 57.6 bits (133), Expect = 5e-08
Identities = 49/201 (24%), Positives = 89/201 (44%), Gaps = 13/201 (6%)
Frame = +3
Query: 63 YSCYRFLLTCAIAS---AAECENATSLSLMIDSLLATYDRDSPP--DSKIVVNLTLHLRH 227
+SC F AS AAE + + + L Y P D+ V+N+TL +
Sbjct: 5 HSCISFCWIYFAASRLRAAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQITL 64
Query: 228 ANIRESESTVRIQAD---LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAA 395
+ I++ + +I ++ W D L+W+ ++ G + + S+ +WRPD+VL N A
Sbjct: 65 SQIKDMDERNQILTAYLWIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKAD 124
Query: 396 TTAGD-YALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCAFKFGSRMHNSDEMD 572
+ + + +G ++W + + + +P D Q C FGS +N +++D
Sbjct: 125 DESSEPVNTNVVLRYDGLITWDAPAITKSSCVVDVTYFPFDNQQCNLTFGSWTYNGNQVD 184
Query: 573 F--VIDXRIYSMF-ESGXWDV 626
+D S F E W+V
Sbjct: 185 IFNALDSGDLSDFIEDVEWEV 205
>BC113549-1|AAI13550.1| 479|Homo sapiens cholinergic receptor,
nicotinic, alpha 9 protein.
Length = 479
Score = 57.6 bits (133), Expect = 5e-08
Identities = 49/201 (24%), Positives = 89/201 (44%), Gaps = 13/201 (6%)
Frame = +3
Query: 63 YSCYRFLLTCAIAS---AAECENATSLSLMIDSLLATYDRDSPP--DSKIVVNLTLHLRH 227
+SC F AS AAE + + + L Y P D+ V+N+TL +
Sbjct: 5 HSCISFCWIYFAASRLRAAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQITL 64
Query: 228 ANIRESESTVRIQAD---LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAA 395
+ I++ + +I ++ W D L+W+ ++ G + + S+ +WRPD+VL N A
Sbjct: 65 SQIKDMDERNQILTAYLWIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKAD 124
Query: 396 TTAGD-YALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCAFKFGSRMHNSDEMD 572
+ + + +G ++W + + + +P D Q C FGS +N +++D
Sbjct: 125 DESSEPVNTNVVLRYDGLITWDAPAITKSSCVVDVTYFPFDNQQCNLTFGSWTYNGNQVD 184
Query: 573 F--VIDXRIYSMF-ESGXWDV 626
+D S F E W+V
Sbjct: 185 IFNALDSGDLSDFIEDVEWEV 205
>AY123244-1|AAM74523.1| 479|Homo sapiens nicotinic acetylcholine
receptor subunit alpha 9 protein.
Length = 479
Score = 57.6 bits (133), Expect = 5e-08
Identities = 49/201 (24%), Positives = 89/201 (44%), Gaps = 13/201 (6%)
Frame = +3
Query: 63 YSCYRFLLTCAIAS---AAECENATSLSLMIDSLLATYDRDSPP--DSKIVVNLTLHLRH 227
+SC F AS AAE + + + L Y P D+ V+N+TL +
Sbjct: 5 HSCISFCWIYFAASRLRAAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQITL 64
Query: 228 ANIRESESTVRIQAD---LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAA 395
+ I++ + +I ++ W D L+W+ ++ G + + S+ +WRPD+VL N A
Sbjct: 65 SQIKDMDERNQILTAYLWIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKAD 124
Query: 396 TTAGD-YALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCAFKFGSRMHNSDEMD 572
+ + + +G ++W + + + +P D Q C FGS +N +++D
Sbjct: 125 DESSEPVNTNVVLRYDGLITWDAPAITKSSCVVDVTYFPFDNQQCNLTFGSWTYNGNQVD 184
Query: 573 F--VIDXRIYSMF-ESGXWDV 626
+D S F E W+V
Sbjct: 185 IFNALDSGDLSDFIEDVEWEV 205
>AJ243342-1|CAB65091.1| 479|Homo sapiens nicotinic acetylcholine
receptor alpha 9 subunit protein.
Length = 479
Score = 57.6 bits (133), Expect = 5e-08
Identities = 49/201 (24%), Positives = 89/201 (44%), Gaps = 13/201 (6%)
Frame = +3
Query: 63 YSCYRFLLTCAIAS---AAECENATSLSLMIDSLLATYDRDSPP--DSKIVVNLTLHLRH 227
+SC F AS AAE + + + L Y P D+ V+N+TL +
Sbjct: 5 HSCISFCWIYFAASRLRAAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQITL 64
Query: 228 ANIRESESTVRIQAD---LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAA 395
+ I++ + +I ++ W D L+W+ ++ G + + S+ +WRPD+VL N A
Sbjct: 65 SQIKDMDERNQILTAYLWIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKAD 124
Query: 396 TTAGD-YALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCAFKFGSRMHNSDEMD 572
+ + + +G ++W + + + +P D Q C FGS +N +++D
Sbjct: 125 DESSEPVNTNVVLRYDGLITWDAPAITKSSCVVDVTYFPFDNQQCNLTFGSWTYNGNQVD 184
Query: 573 F--VIDXRIYSMF-ESGXWDV 626
+D S F E W+V
Sbjct: 185 IFNALDSGDLSDFIEDVEWEV 205
>AC118275-1|AAY40986.1| 479|Homo sapiens unknown protein.
Length = 479
Score = 57.6 bits (133), Expect = 5e-08
Identities = 49/201 (24%), Positives = 89/201 (44%), Gaps = 13/201 (6%)
Frame = +3
Query: 63 YSCYRFLLTCAIAS---AAECENATSLSLMIDSLLATYDRDSPP--DSKIVVNLTLHLRH 227
+SC F AS AAE + + + L Y P D+ V+N+TL +
Sbjct: 5 HSCISFCWIYFAASRLRAAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQITL 64
Query: 228 ANIRESESTVRIQAD---LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAA 395
+ I++ + +I ++ W D L+W+ ++ G + + S+ +WRPD+VL N A
Sbjct: 65 SQIKDMDERNQILTAYLWIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKAD 124
Query: 396 TTAGD-YALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCAFKFGSRMHNSDEMD 572
+ + + +G ++W + + + +P D Q C FGS +N +++D
Sbjct: 125 DESSEPVNTNVVLRYDGLITWDAPAITKSSCVVDVTYFPFDNQQCNLTFGSWTYNGNQVD 184
Query: 573 F--VIDXRIYSMF-ESGXWDV 626
+D S F E W+V
Sbjct: 185 IFNALDSGDLSDFIEDVEWEV 205
>X55019-1|CAA38759.1| 517|Homo sapiens acetylcholine receptor delta
subunit protein.
Length = 517
Score = 57.2 bits (132), Expect = 7e-08
Identities = 35/131 (26%), Positives = 62/131 (47%), Gaps = 3/131 (2%)
Frame = +3
Query: 186 DSKIVVNLTLHLRHA-NIRESESTVRIQADLQMNWIDKRLSWNAGEWG-CSTWLVSSERL 359
+ + V L L L + +++E E T+ ++ W D RL WNA E+G S + + +
Sbjct: 49 EESVDVALALTLSNLISLKEVEETLTTNVWIEHGWTDNRLKWNAEEFGNISVLRLPPDMV 108
Query: 360 WRPDVVL-LNAAATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCAFK 536
W P++VL N + Y+ V + G V W+ + + + +P D Q C+ K
Sbjct: 109 WLPEIVLENNNDGSFQISYSCNVLVYHYGFVYWLPPAIFRSSCPISVTYFPFDWQNCSLK 168
Query: 537 FGSRMHNSDEM 569
F S + + E+
Sbjct: 169 FSSLKYTAKEI 179
>BC101185-1|AAI01186.1| 374|Homo sapiens HTR3E protein protein.
Length = 374
Score = 57.2 bits (132), Expect = 7e-08
Identities = 32/133 (24%), Positives = 63/133 (47%), Gaps = 9/133 (6%)
Frame = +3
Query: 273 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 449
L+M W + +SWN E G + ++++ LW PD+ ++ L A VSN G +
Sbjct: 20 LEMVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEGRI 79
Query: 450 SWIKRLDISTPISMQLDNWPNDMQTCAFKFGSRMHNSDEMDFVIDXRIYSMFES------ 611
+ K + + + ++ + +P D Q C F S ++ D M ++ ++ + ++
Sbjct: 80 RYKKPMKVDSICNLDIFYFPFDQQNCTLTFSSFLYTVDSMLLDMEKEVWEITDASRNILQ 139
Query: 612 --GXWDVTALSSA 644
G W++ LS A
Sbjct: 140 THGEWELLGLSKA 152
>BC093925-1|AAH93925.1| 517|Homo sapiens cholinergic receptor,
nicotinic, delta protein.
Length = 517
Score = 57.2 bits (132), Expect = 7e-08
Identities = 35/131 (26%), Positives = 62/131 (47%), Gaps = 3/131 (2%)
Frame = +3
Query: 186 DSKIVVNLTLHLRHA-NIRESESTVRIQADLQMNWIDKRLSWNAGEWG-CSTWLVSSERL 359
+ + V L L L + +++E E T+ ++ W D RL WNA E+G S + + +
Sbjct: 49 EESVDVALALTLSNLISLKEVEETLTTNVWIEHGWTDNRLKWNAEEFGNISVLRLPPDMV 108
Query: 360 WRPDVVL-LNAAATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCAFK 536
W P++VL N + Y+ V + G V W+ + + + +P D Q C+ K
Sbjct: 109 WLPEIVLENNNDGSFQISYSCNVLVYHYGFVYWLPPAIFRSSCPISVTYFPFDWQNCSLK 168
Query: 537 FGSRMHNSDEM 569
F S + + E+
Sbjct: 169 FSSLKYTAKEI 179
>BC093923-1|AAH93923.1| 517|Homo sapiens cholinergic receptor,
nicotinic, delta protein.
Length = 517
Score = 57.2 bits (132), Expect = 7e-08
Identities = 35/131 (26%), Positives = 62/131 (47%), Gaps = 3/131 (2%)
Frame = +3
Query: 186 DSKIVVNLTLHLRHA-NIRESESTVRIQADLQMNWIDKRLSWNAGEWG-CSTWLVSSERL 359
+ + V L L L + +++E E T+ ++ W D RL WNA E+G S + + +
Sbjct: 49 EESVDVALALTLSNLISLKEVEETLTTNVWIEHGWTDNRLKWNAEEFGNISVLRLPPDMV 108
Query: 360 WRPDVVL-LNAAATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCAFK 536
W P++VL N + Y+ V + G V W+ + + + +P D Q C+ K
Sbjct: 109 WLPEIVLENNNDGSFQISYSCNVLVYHYGFVYWLPPAIFRSSCPISVTYFPFDWQNCSLK 168
Query: 537 FGSRMHNSDEM 569
F S + + E+
Sbjct: 169 FSSLKYTAKEI 179
>AC092165-2|AAY24102.1| 517|Homo sapiens unknown protein.
Length = 517
Score = 57.2 bits (132), Expect = 7e-08
Identities = 35/131 (26%), Positives = 62/131 (47%), Gaps = 3/131 (2%)
Frame = +3
Query: 186 DSKIVVNLTLHLRHA-NIRESESTVRIQADLQMNWIDKRLSWNAGEWG-CSTWLVSSERL 359
+ + V L L L + +++E E T+ ++ W D RL WNA E+G S + + +
Sbjct: 49 EESVDVALALTLSNLISLKEVEETLTTNVWIEHGWTDNRLKWNAEEFGNISVLRLPPDMV 108
Query: 360 WRPDVVL-LNAAATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCAFK 536
W P++VL N + Y+ V + G V W+ + + + +P D Q C+ K
Sbjct: 109 WLPEIVLENNNDGSFQISYSCNVLVYHYGFVYWLPPAIFRSSCPISVTYFPFDWQNCSLK 168
Query: 537 FGSRMHNSDEM 569
F S + + E+
Sbjct: 169 FSSLKYTAKEI 179
>BC131799-1|AAI31800.1| 447|Homo sapiens 5-hydroxytryptamine
(serotonin) receptor 3, family member C protein.
Length = 447
Score = 56.8 bits (131), Expect = 9e-08
Identities = 30/147 (20%), Positives = 68/147 (46%), Gaps = 9/147 (6%)
Frame = +3
Query: 273 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 449
+ + W + ++WN E G + V +E LW PD+ ++ + L A +S+ G +
Sbjct: 91 MDLVWDNPFINWNPKECVGINKLTVLAENLWLPDIFIVESMDVDQTPSGLTAYISSEGRI 150
Query: 450 SWIKRLDISTPISMQLDNWPNDMQTCAFKFGSRMHNSDEMDFVIDXRIYSMFES------ 611
+ K + +++ ++ + +P D Q C F F S ++ D M +D ++ + ++
Sbjct: 151 KYDKPMRVTSICNLDIFYFPFDQQNCTFTFSSFLYTVDSMLLGMDKEVWEITDTSRKVIQ 210
Query: 612 --GXWDVTALSSAVXSPGTGGEVXARV 686
G W++ ++ A G + ++
Sbjct: 211 TQGEWELLGINKATPKMSMGNNLYDQI 237
>U40583-1|AAA83561.1| 502|Homo sapiens alpha 7 neuronal nicotinic
acetylcholine receptor protein.
Length = 502
Score = 56.4 bits (130), Expect = 1e-07
Identities = 39/157 (24%), Positives = 71/157 (45%), Gaps = 3/157 (1%)
Frame = +3
Query: 174 DSPPDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSS 350
DS P + + +L L L+ ++ E + LQM+W D L WN E+ G T
Sbjct: 47 DSQPLT-VYFSLNL-LQIMDVDEKNQVLTTNIWLQMSWTDHYLQWNVSEYPGVKTVRFPD 104
Query: 351 ERLWRPDVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTC 527
++W+PD++L N+A + V+ +G ++ + + + +P D+Q C
Sbjct: 105 GQIWKPDILLYNSADERFDATFHTNVLVNPSGHCQYLPPGIFKSSCYIDVRWFPFDVQHC 164
Query: 528 AFKFGSRMHNSDEMDFVI-DXRIYSMFESGXWDVTAL 635
KFGS + +D + + I +G WD+ +
Sbjct: 165 KLKFGSWSYGGWSLDLQMQEADISGYIPNGEWDLVGI 201
>AF459285-1|AAL66182.1| 447|Homo sapiens 5-hydroxytryptamine
receptor 3 subunit C protein.
Length = 447
Score = 56.4 bits (130), Expect = 1e-07
Identities = 30/147 (20%), Positives = 67/147 (45%), Gaps = 9/147 (6%)
Frame = +3
Query: 273 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 449
+ + W + ++WN E G + V +E LW PD+ ++ + L A +S+ G +
Sbjct: 91 MDLVWDNPFINWNPKECVGINKLTVLAENLWLPDIFIVESMDVDQTPSGLTAYISSEGRI 150
Query: 450 SWIKRLDISTPISMQLDNWPNDMQTCAFKFGSRMHNSDEMDFVIDXRIYSMFES------ 611
+ K + +++ + + +P D Q C F F S ++ D M +D ++ + ++
Sbjct: 151 KYDKPMRVTSICKLDIFYFPFDQQNCTFTFSSFLYTVDSMLLGMDKEVWEITDTSRKVIQ 210
Query: 612 --GXWDVTALSSAVXSPGTGGEVXARV 686
G W++ ++ A G + ++
Sbjct: 211 TQGEWELLGINKATPKMSMGNNLYDQI 237
>AF385585-1|AAK68111.1| 502|Homo sapiens nicotinic cholinergic
receptor alpha 7 protein.
Length = 502
Score = 56.4 bits (130), Expect = 1e-07
Identities = 39/157 (24%), Positives = 71/157 (45%), Gaps = 3/157 (1%)
Frame = +3
Query: 174 DSPPDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSS 350
DS P + + +L L L+ ++ E + LQM+W D L WN E+ G T
Sbjct: 47 DSQPLT-VYFSLNL-LQIMDVDEKNQVLTTNIWLQMSWTDHYLQWNVSEYPGVKTVRFPD 104
Query: 351 ERLWRPDVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTC 527
++W+PD++L N+A + V+ +G ++ + + + +P D+Q C
Sbjct: 105 GQIWKPDILLYNSADERFDATFHTNVLVNPSGHCQYLPPGIFKSSCYIDVRWFPFDVQHC 164
Query: 528 AFKFGSRMHNSDEMDFVI-DXRIYSMFESGXWDVTAL 635
KFGS + +D + + I +G WD+ +
Sbjct: 165 KLKFGSWSYGGWSLDLQMQEADISGYIPNGEWDLVGI 201
>AF227732-1|AAF61920.1| 470|Homo sapiens nicotinic acetylcholine
receptor alpha 9 subunit protein.
Length = 470
Score = 56.4 bits (130), Expect = 1e-07
Identities = 44/184 (23%), Positives = 83/184 (45%), Gaps = 10/184 (5%)
Frame = +3
Query: 105 AAECENATSLSLMIDSLLATYDRDSPP--DSKIVVNLTLHLRHANIRESESTVRIQAD-- 272
AAE + + + L Y P D+ V+N+TL + + I++ + +I
Sbjct: 16 AAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQITLSQIKDMDERNQILTAYL 75
Query: 273 -LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGD-YALRARVSNNG 443
++ W D L+W+ ++ G + + S+ +WRPD+VL N A + + + +G
Sbjct: 76 WIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKADDESSEPVNTNVVLRYDG 135
Query: 444 SVSWIKRLDISTPISMQLDNWPNDMQTCAFKFGSRMHNSDEMDF--VIDXRIYSMF-ESG 614
++W + + + +P D Q C FGS +N +++D +D S F E
Sbjct: 136 LITWDAPAITKSSCVVDVTYFPFDNQQCNLTFGSWTYNGNQVDIFNALDSGDLSDFIEDV 195
Query: 615 XWDV 626
W+V
Sbjct: 196 EWEV 199
>S77554-1|AAB33983.1| 474|Homo sapiens GABAA receptor beta 2
subunit protein.
Length = 474
Score = 55.2 bits (127), Expect = 3e-07
Identities = 43/182 (23%), Positives = 79/182 (43%), Gaps = 10/182 (5%)
Frame = +3
Query: 60 YYSCYRFLLTCAIASAAECENATSLSLM---IDSLLATYDRDSPPD---SKIVVNLTLHL 221
Y+ + F L A A + +++SL+ +D LL YD PD + V + + +
Sbjct: 9 YFGIWSFPLIIAAVCAQSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDI 68
Query: 222 RHAN-IRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAAT 398
+ + E + Q W DKRLS+N + +++LW PD LN +
Sbjct: 69 ASIDMVSEVNMDYTLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLNDKKS 128
Query: 399 TAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCAFKFGSRMHNSDEM 569
++ R+ +G+V + R+ + M L +P D Q C + S + +D++
Sbjct: 129 FVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDI 188
Query: 570 DF 575
+F
Sbjct: 189 EF 190
>S77553-1|AAB33982.1| 512|Homo sapiens GABAA receptor beta 2
subunit protein.
Length = 512
Score = 55.2 bits (127), Expect = 3e-07
Identities = 43/182 (23%), Positives = 79/182 (43%), Gaps = 10/182 (5%)
Frame = +3
Query: 60 YYSCYRFLLTCAIASAAECENATSLSLM---IDSLLATYDRDSPPD---SKIVVNLTLHL 221
Y+ + F L A A + +++SL+ +D LL YD PD + V + + +
Sbjct: 9 YFGIWSFPLIIAAVCAQSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDI 68
Query: 222 RHAN-IRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAAT 398
+ + E + Q W DKRLS+N + +++LW PD LN +
Sbjct: 69 ASIDMVSEVNMDYTLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLNDKKS 128
Query: 399 TAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCAFKFGSRMHNSDEM 569
++ R+ +G+V + R+ + M L +P D Q C + S + +D++
Sbjct: 129 FVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDI 188
Query: 570 DF 575
+F
Sbjct: 189 EF 190
>S67368-1|AAB29370.1| 474|Homo sapiens gamma-aminobutyric acid A
receptor beta 2 subunit protein.
Length = 474
Score = 55.2 bits (127), Expect = 3e-07
Identities = 43/182 (23%), Positives = 79/182 (43%), Gaps = 10/182 (5%)
Frame = +3
Query: 60 YYSCYRFLLTCAIASAAECENATSLSLM---IDSLLATYDRDSPPD---SKIVVNLTLHL 221
Y+ + F L A A + +++SL+ +D LL YD PD + V + + +
Sbjct: 9 YFGIWSFPLIIAAVCAQSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDI 68
Query: 222 RHAN-IRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAAT 398
+ + E + Q W DKRLS+N + +++LW PD LN +
Sbjct: 69 ASIDMVSEVNMDYTLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLNDKKS 128
Query: 399 TAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCAFKFGSRMHNSDEM 569
++ R+ +G+V + R+ + M L +P D Q C + S + +D++
Sbjct: 129 FVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDI 188
Query: 570 DF 575
+F
Sbjct: 189 EF 190
>BC105639-1|AAI05640.1| 474|Homo sapiens GABRB2 protein protein.
Length = 474
Score = 55.2 bits (127), Expect = 3e-07
Identities = 43/182 (23%), Positives = 79/182 (43%), Gaps = 10/182 (5%)
Frame = +3
Query: 60 YYSCYRFLLTCAIASAAECENATSLSLM---IDSLLATYDRDSPPD---SKIVVNLTLHL 221
Y+ + F L A A + +++SL+ +D LL YD PD + V + + +
Sbjct: 9 YFGIWSFPLIIAAVCAQSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDI 68
Query: 222 RHAN-IRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAAT 398
+ + E + Q W DKRLS+N + +++LW PD LN +
Sbjct: 69 ASIDMVSEVNMDYTLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLNDKKS 128
Query: 399 TAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCAFKFGSRMHNSDEM 569
++ R+ +G+V + R+ + M L +P D Q C + S + +D++
Sbjct: 129 FVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDI 188
Query: 570 DF 575
+F
Sbjct: 189 EF 190
>BC099719-1|AAH99719.1| 474|Homo sapiens GABRB2 protein protein.
Length = 474
Score = 55.2 bits (127), Expect = 3e-07
Identities = 43/182 (23%), Positives = 79/182 (43%), Gaps = 10/182 (5%)
Frame = +3
Query: 60 YYSCYRFLLTCAIASAAECENATSLSLM---IDSLLATYDRDSPPD---SKIVVNLTLHL 221
Y+ + F L A A + +++SL+ +D LL YD PD + V + + +
Sbjct: 9 YFGIWSFPLIIAAVCAQSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDI 68
Query: 222 RHAN-IRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAAT 398
+ + E + Q W DKRLS+N + +++LW PD LN +
Sbjct: 69 ASIDMVSEVNMDYTLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLNDKKS 128
Query: 399 TAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCAFKFGSRMHNSDEM 569
++ R+ +G+V + R+ + M L +P D Q C + S + +D++
Sbjct: 129 FVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDI 188
Query: 570 DF 575
+F
Sbjct: 189 EF 190
>BC099705-1|AAH99705.1| 474|Homo sapiens GABRB2 protein protein.
Length = 474
Score = 55.2 bits (127), Expect = 3e-07
Identities = 43/182 (23%), Positives = 79/182 (43%), Gaps = 10/182 (5%)
Frame = +3
Query: 60 YYSCYRFLLTCAIASAAECENATSLSLM---IDSLLATYDRDSPPD---SKIVVNLTLHL 221
Y+ + F L A A + +++SL+ +D LL YD PD + V + + +
Sbjct: 9 YFGIWSFPLIIAAVCAQSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDI 68
Query: 222 RHAN-IRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAAT 398
+ + E + Q W DKRLS+N + +++LW PD LN +
Sbjct: 69 ASIDMVSEVNMDYTLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLNDKKS 128
Query: 399 TAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCAFKFGSRMHNSDEM 569
++ R+ +G+V + R+ + M L +P D Q C + S + +D++
Sbjct: 129 FVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDI 188
Query: 570 DF 575
+F
Sbjct: 189 EF 190
>L08485-1|AAA58490.1| 462|Homo sapiens GABA-benzodiazepine receptor
alpha-5-subunit protein.
Length = 462
Score = 54.8 bits (126), Expect = 4e-07
Identities = 39/161 (24%), Positives = 73/161 (45%), Gaps = 7/161 (4%)
Frame = +3
Query: 117 ENATSLSLMIDSLLATYDRDSPPD--SKIV-VNLTLHLRHAN-IRESESTVRIQADLQMN 284
+N T + ++D LL YD P +I V +++ + ++E I + +
Sbjct: 44 DNITIFTRILDGLLDGYDNRLRPGLGERITQVRTDIYVTSFGPVSDTEMEYTIDVFFRQS 103
Query: 285 WIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSW 455
W D+RL + + + ++W PD N + A + R+ ++G++ +
Sbjct: 104 WKDERLRFKGPMQRLPLNNLLASKIWTPDTFFHNGKKSIAHNMTTPNKLLRLEDDGTLLY 163
Query: 456 IKRLDISTPISMQLDNWPNDMQTCAFKFGSRMHNSDEMDFV 578
RL IS MQL+++P D C KFGS + + E+ +V
Sbjct: 164 TMRLTISAECPMQLEDFPMDAHACPLKFGSYAYPNSEVVYV 204
>BT009830-1|AAP88832.1| 462|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 5 protein.
Length = 462
Score = 54.8 bits (126), Expect = 4e-07
Identities = 39/161 (24%), Positives = 73/161 (45%), Gaps = 7/161 (4%)
Frame = +3
Query: 117 ENATSLSLMIDSLLATYDRDSPPD--SKIV-VNLTLHLRHAN-IRESESTVRIQADLQMN 284
+N T + ++D LL YD P +I V +++ + ++E I + +
Sbjct: 44 DNITIFTRILDGLLDGYDNRLRPGLGERITQVRTDIYVTSFGPVSDTEMEYTIDVFFRQS 103
Query: 285 WIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSW 455
W D+RL + + + ++W PD N + A + R+ ++G++ +
Sbjct: 104 WKDERLRFKGPMQRLPLNNLLASKIWTPDTFFHNGKKSIAHNMTTPNKLLRLEDDGTLLY 163
Query: 456 IKRLDISTPISMQLDNWPNDMQTCAFKFGSRMHNSDEMDFV 578
RL IS MQL+++P D C KFGS + + E+ +V
Sbjct: 164 TMRLTISAECPMQLEDFPMDAHACPLKFGSYAYPNSEVVYV 204
>BC113422-1|AAI13423.1| 462|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 5 protein.
Length = 462
Score = 54.8 bits (126), Expect = 4e-07
Identities = 39/161 (24%), Positives = 73/161 (45%), Gaps = 7/161 (4%)
Frame = +3
Query: 117 ENATSLSLMIDSLLATYDRDSPPD--SKIV-VNLTLHLRHAN-IRESESTVRIQADLQMN 284
+N T + ++D LL YD P +I V +++ + ++E I + +
Sbjct: 44 DNITIFTRILDGLLDGYDNRLRPGLGERITQVRTDIYVTSFGPVSDTEMEYTIDVFFRQS 103
Query: 285 WIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSW 455
W D+RL + + + ++W PD N + A + R+ ++G++ +
Sbjct: 104 WKDERLRFKGPMQRLPLNNLLASKIWTPDTFFHNGKKSIAHNMTTPNKLLRLEDDGTLLY 163
Query: 456 IKRLDISTPISMQLDNWPNDMQTCAFKFGSRMHNSDEMDFV 578
RL IS MQL+++P D C KFGS + + E+ +V
Sbjct: 164 TMRLTISAECPMQLEDFPMDAHACPLKFGSYAYPNSEVVYV 204
>BC111979-1|AAI11980.1| 462|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 5, precursor protein.
Length = 462
Score = 54.8 bits (126), Expect = 4e-07
Identities = 39/161 (24%), Positives = 73/161 (45%), Gaps = 7/161 (4%)
Frame = +3
Query: 117 ENATSLSLMIDSLLATYDRDSPPD--SKIV-VNLTLHLRHAN-IRESESTVRIQADLQMN 284
+N T + ++D LL YD P +I V +++ + ++E I + +
Sbjct: 44 DNITIFTRILDGLLDGYDNRLRPGLGERITQVRTDIYVTSFGPVSDTEMEYTIDVFFRQS 103
Query: 285 WIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSW 455
W D+RL + + + ++W PD N + A + R+ ++G++ +
Sbjct: 104 WKDERLRFKGPMQRLPLNNLLASKIWTPDTFFHNGKKSIAHNMTTPNKLLRLEDDGTLLY 163
Query: 456 IKRLDISTPISMQLDNWPNDMQTCAFKFGSRMHNSDEMDFV 578
RL IS MQL+++P D C KFGS + + E+ +V
Sbjct: 164 TMRLTISAECPMQLEDFPMDAHACPLKFGSYAYPNSEVVYV 204
>BC110597-1|AAI10598.1| 411|Homo sapiens ligand-gated ion channel,
zinc activated 1 protein.
Length = 411
Score = 54.4 bits (125), Expect = 5e-07
Identities = 28/101 (27%), Positives = 49/101 (48%)
Frame = +3
Query: 273 LQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVS 452
L+++W+D RL+WN + E LW P + +L A D + +ARV +G V
Sbjct: 86 LRLSWLDTRLAWNTSAHPRHAITLPWESLWTPRLTILEALWVDWRDQSPQARVDQDGHVK 145
Query: 453 WIKRLDISTPISMQLDNWPNDMQTCAFKFGSRMHNSDEMDF 575
L T + +L ++P D C+ F + + + E++F
Sbjct: 146 LNLALTTETNCNFELLHFPRDHSNCSLSFYALSNTAMELEF 186
>AF512521-1|AAO20969.1| 411|Homo sapiens ligand-gated ion channel
subunit protein.
Length = 411
Score = 54.4 bits (125), Expect = 5e-07
Identities = 28/101 (27%), Positives = 49/101 (48%)
Frame = +3
Query: 273 LQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVS 452
L+++W+D RL+WN + E LW P + +L A D + +ARV +G V
Sbjct: 86 LRLSWLDTRLAWNTSAHPRHAITLPWESLWTPRLTILEALWVDWRDQSPQARVDQDGHVK 145
Query: 453 WIKRLDISTPISMQLDNWPNDMQTCAFKFGSRMHNSDEMDF 575
L T + +L ++P D C+ F + + + E++F
Sbjct: 146 LNLALTTETNCNFELLHFPRDHSNCSLSFYALSNTAMELEF 186
>AB223030-1|BAE19924.1| 411|Homo sapiens ligand-gated ion-channel
receptor L2 protein.
Length = 411
Score = 54.0 bits (124), Expect = 7e-07
Identities = 28/101 (27%), Positives = 49/101 (48%)
Frame = +3
Query: 273 LQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVS 452
L+++W+D RL+WN + E LW P + +L A D + +ARV +G V
Sbjct: 86 LRLSWLDTRLAWNTSAHPRHAITLPWESLWTPRLTILEALWVDWRDQSPQARVDQDGHVK 145
Query: 453 WIKRLDISTPISMQLDNWPNDMQTCAFKFGSRMHNSDEMDF 575
L T + +L ++P D C+ F + + + E++F
Sbjct: 146 LNLALATETNCNFELLHFPRDHSNCSLSFYALSNTAMELEF 186
>BC111802-1|AAI11803.1| 465|Homo sapiens CHRNG protein protein.
Length = 465
Score = 52.8 bits (121), Expect = 2e-06
Identities = 40/133 (30%), Positives = 63/133 (47%), Gaps = 7/133 (5%)
Frame = +3
Query: 81 LLTCAIASAAECENATSLSLMIDSLLATYDRDSPPDSKI--VVNLTLHLRHANI---RES 245
LL A+ A+ N L+ D L+ YD + P + VVN++L L N+ E
Sbjct: 11 LLLLAVCLGAQGRNQEE-RLLAD-LMQNYDPNLRPAERDSDVVNVSLKLTLTNLISLNER 68
Query: 246 ESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAAT-TAGDYAL 419
E + ++M W D RL W+ ++ G V S +WRPD+VL N + T + + L
Sbjct: 69 EEALTTNVWIEMQWCDYRLRWDPRDYEGLWVLRVPSTMVWRPDIVLENKSQTYSTNEIDL 128
Query: 420 RARVSNNGSVSWI 458
+ + S+ WI
Sbjct: 129 QLSQEDGQSIEWI 141
>BC028629-1|AAH28629.1| 492|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 3 protein.
Length = 492
Score = 52.0 bits (119), Expect = 3e-06
Identities = 36/158 (22%), Positives = 70/158 (44%), Gaps = 7/158 (4%)
Frame = +3
Query: 117 ENATSLSLMIDSLLATYDRDSPP---DSKIVVNLTLHLRHAN-IRESESTVRIQADLQMN 284
+N T + ++D LL YD P D+ V +++ + +++ I +
Sbjct: 62 DNITIFTRILDRLLDGYDNRLRPGLGDAVTEVKTDIYVTSFGPVSDTDMEYTIDVFFRQT 121
Query: 285 WIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSW 455
W D+RL ++ + + ++W PD N + A + R+ +NG++ +
Sbjct: 122 WHDERLKFDGPMKILPLNNLLASKIWTPDTFFHNGKKSVAHNMTTPNKLLRLVDNGTLPY 181
Query: 456 IKRLDISTPISMQLDNWPNDMQTCAFKFGSRMHNSDEM 569
RL I M L+++P D+ C KFGS + + E+
Sbjct: 182 TMRLTIHAECPMHLEDFPMDVHACPLKFGSYAYTTAEV 219
>S62908-1|AAB27279.1| 492|Homo sapiens gamma-aminobutyric acidA
receptor alpha 3 subunit protein.
Length = 492
Score = 51.6 bits (118), Expect = 4e-06
Identities = 36/158 (22%), Positives = 70/158 (44%), Gaps = 7/158 (4%)
Frame = +3
Query: 117 ENATSLSLMIDSLLATYDRDSPP---DSKIVVNLTLHLRHAN-IRESESTVRIQADLQMN 284
+N T + ++D LL YD P D+ V +++ + +++ I +
Sbjct: 62 DNITIFTRILDRLLDGYDNRLRPGLGDAVTEVKTDIYVTSFGPVSDTDMEYTIDVFFRQT 121
Query: 285 WIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSW 455
W D+RL ++ + + ++W PD N + A + R+ +NG++ +
Sbjct: 122 WHDERLKFDGPMKILPLNNLLASKIWTPDTFFHNGKKSVAHNMTTPNKLLRLVDNGTLLY 181
Query: 456 IKRLDISTPISMQLDNWPNDMQTCAFKFGSRMHNSDEM 569
RL I M L+++P D+ C KFGS + + E+
Sbjct: 182 TMRLTIHAECPMHLEDFPMDVHACPLKFGSYAYTTAEV 219
>AF166361-1|AAG12455.1| 492|Homo sapiens GABA receptor subunit
alpha 3 protein.
Length = 492
Score = 51.6 bits (118), Expect = 4e-06
Identities = 36/158 (22%), Positives = 70/158 (44%), Gaps = 7/158 (4%)
Frame = +3
Query: 117 ENATSLSLMIDSLLATYDRDSPP---DSKIVVNLTLHLRHAN-IRESESTVRIQADLQMN 284
+N T + ++D LL YD P D+ V +++ + +++ I +
Sbjct: 62 DNITIFTRILDRLLDGYDNRLRPGLGDAVTEVKTDIYVTSFGPVSDTDMEYTIDVFFRQT 121
Query: 285 WIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSW 455
W D+RL ++ + + ++W PD N + A + R+ +NG++ +
Sbjct: 122 WHDERLKFDGPMKILPLNNLLASKIWTPDTFFHNGKKSVAHNMTTPNKLLRLVDNGTLLY 181
Query: 456 IKRLDISTPISMQLDNWPNDMQTCAFKFGSRMHNSDEM 569
RL I M L+++P D+ C KFGS + + E+
Sbjct: 182 TMRLTIHAECPMHLEDFPMDVHACPLKFGSYAYTTAEV 219
>M59216-1|AAA35862.1| 474|Homo sapiens gamma-aminobutyric acid
receptor beta-1 subunit protein.
Length = 474
Score = 50.8 bits (116), Expect = 6e-06
Identities = 39/171 (22%), Positives = 73/171 (42%), Gaps = 7/171 (4%)
Frame = +3
Query: 84 LTCAIASAAECENATSLSLMIDSLLATYDRDSPPD---SKIVVNLTLHLRHAN-IRESES 251
+ C S E N + + +D LL YD PD + V + + + + + E
Sbjct: 21 MVCCAHSTNEPSNMSYVKETVDRLLKGYDIRLRPDFGGPPVDVGMRIDVASIDMVSEVNM 80
Query: 252 TVRIQADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR--- 422
+ Q +W DKRLS++ + +++LW PD LN + ++
Sbjct: 81 DYTLTMYFQQSWKDKRLSYSGIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRM 140
Query: 423 ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCAFKFGSRMHNSDEMDF 575
R+ +G+V + R+ + M L +P D Q C + S + +D+++F
Sbjct: 141 IRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEF 191
>AK122638-1|BAC85499.1| 266|Homo sapiens yte protein of 76kDa)
(LCP2). protein.
Length = 266
Score = 50.8 bits (116), Expect = 6e-06
Identities = 26/89 (29%), Positives = 42/89 (47%)
Frame = +3
Query: 273 LQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVS 452
L+++W+D RL+WN + E LW P + +L A D + +ARV +G V
Sbjct: 87 LRLSWLDTRLAWNTSAHPRHAITLPWESLWTPRLTILEALWVDWRDQSPQARVDQDGHVK 146
Query: 453 WIKRLDISTPISMQLDNWPNDMQTCAFKF 539
L T + +L ++P D C+ F
Sbjct: 147 LNLALTTETNCNFELLHFPRDHSNCSLSF 175
>S82769-1|AAB39369.1| 467|Homo sapiens GABAA receptor gamma 3
subunit protein.
Length = 467
Score = 50.4 bits (115), Expect = 8e-06
Identities = 37/155 (23%), Positives = 67/155 (43%), Gaps = 7/155 (4%)
Frame = +3
Query: 126 TSLSLMIDSLLATYDRDSPPDSKI---VVNLTLHLRHAN-IRESESTVRIQADLQMNWID 293
T ++L+++ LL YD+ PD I V+++ +++ + +I W D
Sbjct: 45 TDVTLILNKLLREYDKKLRPDIGIKPTVIDVDIYVNSIGPVSSINMEYQIDIFFAQTWTD 104
Query: 294 KRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKR 464
RL +N+ + +W PD + N+ A R+ N+G + + R
Sbjct: 105 SRLRFNSTMKILTLNSNMVGLIWIPDTIFRNSKTAEAHWITTPNQLLRIWNDGKILYTLR 164
Query: 465 LDISTPISMQLDNWPNDMQTCAFKFGSRMHNSDEM 569
L I+ +QL N+P D +C F S + +EM
Sbjct: 165 LTINAECQLQLHNFPMDEHSCPLIFSSYGYPKEEM 199
>AF269144-1|AAF99698.1| 467|Homo sapiens GABAA receptor gamma 3
subunit protein.
Length = 467
Score = 50.4 bits (115), Expect = 8e-06
Identities = 37/155 (23%), Positives = 67/155 (43%), Gaps = 7/155 (4%)
Frame = +3
Query: 126 TSLSLMIDSLLATYDRDSPPDSKI---VVNLTLHLRHAN-IRESESTVRIQADLQMNWID 293
T ++L+++ LL YD+ PD I V+++ +++ + +I W D
Sbjct: 45 TDVTLILNKLLREYDKKLRPDIGIKPTVIDVDIYVNSIGPVSSINMEYQIDIFFAQTWTD 104
Query: 294 KRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKR 464
RL +N+ + +W PD + N+ A R+ N+G + + R
Sbjct: 105 SRLRFNSTMKILTLNSNMVGLIWIPDTIFRNSKTAEAHWITTPNQLLRIWNDGKILYTLR 164
Query: 465 LDISTPISMQLDNWPNDMQTCAFKFGSRMHNSDEM 569
L I+ +QL N+P D +C F S + +EM
Sbjct: 165 LTINAECQLQLHNFPMDEHSCPLIFSSYGYPKEEM 199
>AF228458-1|AAF63215.1| 449|Homo sapiens GABAA receptor gamma 3
subunit protein.
Length = 449
Score = 50.4 bits (115), Expect = 8e-06
Identities = 37/155 (23%), Positives = 67/155 (43%), Gaps = 7/155 (4%)
Frame = +3
Query: 126 TSLSLMIDSLLATYDRDSPPDSKI---VVNLTLHLRHAN-IRESESTVRIQADLQMNWID 293
T ++L+++ LL YD+ PD I V+++ +++ + +I W D
Sbjct: 27 TDVTLILNKLLREYDKKLRPDIGIKPTVIDVDIYVNSIGPVSSINMEYQIDIFFAQTWTD 86
Query: 294 KRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKR 464
RL +N+ + +W PD + N+ A R+ N+G + + R
Sbjct: 87 SRLRFNSTMKILTLNSNMVGLIWIPDTIFRNSKTAEAHWITTPNQLLRIWNDGKILYTLR 146
Query: 465 LDISTPISMQLDNWPNDMQTCAFKFGSRMHNSDEM 569
L I+ +QL N+P D +C F S + +EM
Sbjct: 147 LTINAECQLQLHNFPMDEHSCPLIFSSYGYPKEEM 181
>X14767-1|CAA32875.1| 474|Homo sapiens GABA-A receptor beta 1
subunit protein.
Length = 474
Score = 50.0 bits (114), Expect = 1e-05
Identities = 39/171 (22%), Positives = 72/171 (42%), Gaps = 7/171 (4%)
Frame = +3
Query: 84 LTCAIASAAECENATSLSLMIDSLLATYDRDSPPD---SKIVVNLTLHLRHAN-IRESES 251
+ C S E N + +D LL YD PD + V + + + + + E
Sbjct: 21 MVCCAHSTNEPSNMPYVKETVDRLLKGYDIRLRPDFGGPPVDVGMRIDVASIDMVSEVNM 80
Query: 252 TVRIQADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR--- 422
+ Q +W DKRLS++ + +++LW PD LN + ++
Sbjct: 81 DYTLTMYFQQSWKDKRLSYSGIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRM 140
Query: 423 ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCAFKFGSRMHNSDEMDF 575
R+ +G+V + R+ + M L +P D Q C + S + +D+++F
Sbjct: 141 IRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEF 191
>AJ003080-1|CAA05853.1| 238|Homo sapiens serotonin receptor
protein.
Length = 238
Score = 50.0 bits (114), Expect = 1e-05
Identities = 27/111 (24%), Positives = 49/111 (44%), Gaps = 1/111 (0%)
Frame = +3
Query: 231 NIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAG 407
N+ E + + W D+ L WN ++ T L + ++ +W PD+++
Sbjct: 72 NVDEKNQVLTTYIWYRQYWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKS 131
Query: 408 DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCAFKFGSRMHNS 560
+ + G V K L + T S+ + N+P D+Q C+ F S +H S
Sbjct: 132 PNIPYVYIRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLHTS 182
>S82612-1|AAB37533.2| 478|Homo sapiens 5-hydroxytryptamine type 3AS
receptor subunit protein.
Length = 478
Score = 49.6 bits (113), Expect = 1e-05
Identities = 26/115 (22%), Positives = 51/115 (44%), Gaps = 1/115 (0%)
Frame = +3
Query: 231 NIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAG 407
N+ E + + W D+ L WN ++ T L + ++ +W PD+++
Sbjct: 72 NVDEKNQVLTTYIWYRQYWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINELVDVGKS 131
Query: 408 DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCAFKFGSRMHNSDEMD 572
+ + G V K L + T S+ + N+P D+Q C+ F S +H +++
Sbjct: 132 PNIPYVYIRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLHTIQDIN 186
>S81944-1|AAB36480.1| 453|Homo sapiens gamma-aminobutyric acid type
A receptor alpha 6 subunit protein.
Length = 453
Score = 49.2 bits (112), Expect = 2e-05
Identities = 36/154 (23%), Positives = 65/154 (42%), Gaps = 7/154 (4%)
Frame = +3
Query: 129 SLSLMIDSLLATYDRDSPPD---SKIVVNLTLHLRHAN-IRESESTVRIQADLQMNWIDK 296
++S ++D+LL YD P + V +++ + + E + + W D+
Sbjct: 31 NVSRILDNLLEGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTDE 90
Query: 297 RLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRA---RVSNNGSVSWIKRL 467
RL + S + ++W PD N + A + R+ NG++ + RL
Sbjct: 91 RLKFGGPTEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTMRL 150
Query: 468 DISTPISMQLDNWPNDMQTCAFKFGSRMHNSDEM 569
I+ M+L N+P D C KFGS + E+
Sbjct: 151 TINADCPMRLVNFPMDGHACPLKFGSYAYPKSEI 184
>D49394-1|BAA08387.1| 478|Homo sapiens serotonin 5-HT3 receptor
protein.
Length = 478
Score = 49.2 bits (112), Expect = 2e-05
Identities = 26/115 (22%), Positives = 51/115 (44%), Gaps = 1/115 (0%)
Frame = +3
Query: 231 NIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAG 407
N+ E + + W D+ L WN ++ T L + ++ +W PD+++
Sbjct: 72 NVDEKNQVLTTYIWYRQYWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKS 131
Query: 408 DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCAFKFGSRMHNSDEMD 572
+ + G V K L + T S+ + N+P D+Q C+ F S +H +++
Sbjct: 132 PNIPYVYIRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLHTIQDIN 186
>BT007204-1|AAP35868.1| 484|Homo sapiens 5-hydroxytryptamine
(serotonin) receptor 3A protein.
Length = 484
Score = 49.2 bits (112), Expect = 2e-05
Identities = 26/115 (22%), Positives = 51/115 (44%), Gaps = 1/115 (0%)
Frame = +3
Query: 231 NIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAG 407
N+ E + + W D+ L WN ++ T L + ++ +W PD+++
Sbjct: 78 NVDEKNQVLTTYIWYRQYWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKS 137
Query: 408 DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCAFKFGSRMHNSDEMD 572
+ + G V K L + T S+ + N+P D+Q C+ F S +H +++
Sbjct: 138 PNIPYVYIRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLHTIQDIN 192
>BC099641-1|AAH99641.1| 453|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 6 protein.
Length = 453
Score = 49.2 bits (112), Expect = 2e-05
Identities = 36/154 (23%), Positives = 65/154 (42%), Gaps = 7/154 (4%)
Frame = +3
Query: 129 SLSLMIDSLLATYDRDSPPD---SKIVVNLTLHLRHAN-IRESESTVRIQADLQMNWIDK 296
++S ++D+LL YD P + V +++ + + E + + W D+
Sbjct: 31 NVSRILDNLLEGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTDE 90
Query: 297 RLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRA---RVSNNGSVSWIKRL 467
RL + S + ++W PD N + A + R+ NG++ + RL
Sbjct: 91 RLKFGGPTEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTMRL 150
Query: 468 DISTPISMQLDNWPNDMQTCAFKFGSRMHNSDEM 569
I+ M+L N+P D C KFGS + E+
Sbjct: 151 TINADCPMRLVNFPMDGHACPLKFGSYAYPKSEI 184
>BC099640-1|AAH99640.1| 453|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 6 protein.
Length = 453
Score = 49.2 bits (112), Expect = 2e-05
Identities = 36/154 (23%), Positives = 65/154 (42%), Gaps = 7/154 (4%)
Frame = +3
Query: 129 SLSLMIDSLLATYDRDSPPD---SKIVVNLTLHLRHAN-IRESESTVRIQADLQMNWIDK 296
++S ++D+LL YD P + V +++ + + E + + W D+
Sbjct: 31 NVSRILDNLLEGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTDE 90
Query: 297 RLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRA---RVSNNGSVSWIKRL 467
RL + S + ++W PD N + A + R+ NG++ + RL
Sbjct: 91 RLKFGGPTEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTMRL 150
Query: 468 DISTPISMQLDNWPNDMQTCAFKFGSRMHNSDEM 569
I+ M+L N+P D C KFGS + E+
Sbjct: 151 TINADCPMRLVNFPMDGHACPLKFGSYAYPKSEI 184
>BC096242-1|AAH96242.1| 453|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 6 protein.
Length = 453
Score = 49.2 bits (112), Expect = 2e-05
Identities = 36/154 (23%), Positives = 65/154 (42%), Gaps = 7/154 (4%)
Frame = +3
Query: 129 SLSLMIDSLLATYDRDSPPD---SKIVVNLTLHLRHAN-IRESESTVRIQADLQMNWIDK 296
++S ++D+LL YD P + V +++ + + E + + W D+
Sbjct: 31 NVSRILDNLLEGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTDE 90
Query: 297 RLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRA---RVSNNGSVSWIKRL 467
RL + S + ++W PD N + A + R+ NG++ + RL
Sbjct: 91 RLKFGGPTEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTMRL 150
Query: 468 DISTPISMQLDNWPNDMQTCAFKFGSRMHNSDEM 569
I+ M+L N+P D C KFGS + E+
Sbjct: 151 TINADCPMRLVNFPMDGHACPLKFGSYAYPKSEI 184
>BC096241-1|AAH96241.1| 453|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 6 protein.
Length = 453
Score = 49.2 bits (112), Expect = 2e-05
Identities = 36/154 (23%), Positives = 65/154 (42%), Gaps = 7/154 (4%)
Frame = +3
Query: 129 SLSLMIDSLLATYDRDSPPD---SKIVVNLTLHLRHAN-IRESESTVRIQADLQMNWIDK 296
++S ++D+LL YD P + V +++ + + E + + W D+
Sbjct: 31 NVSRILDNLLEGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTDE 90
Query: 297 RLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRA---RVSNNGSVSWIKRL 467
RL + S + ++W PD N + A + R+ NG++ + RL
Sbjct: 91 RLKFGGPTEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTMRL 150
Query: 468 DISTPISMQLDNWPNDMQTCAFKFGSRMHNSDEM 569
I+ M+L N+P D C KFGS + E+
Sbjct: 151 TINADCPMRLVNFPMDGHACPLKFGSYAYPKSEI 184
>BC004453-1|AAH04453.2| 478|Homo sapiens 5-hydroxytryptamine
(serotonin) receptor 3A protein.
Length = 478
Score = 49.2 bits (112), Expect = 2e-05
Identities = 26/115 (22%), Positives = 51/115 (44%), Gaps = 1/115 (0%)
Frame = +3
Query: 231 NIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAG 407
N+ E + + W D+ L WN ++ T L + ++ +W PD+++
Sbjct: 72 NVDEKNQVLTTYIWYRQYWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKS 131
Query: 408 DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCAFKFGSRMHNSDEMD 572
+ + G V K L + T S+ + N+P D+Q C+ F S +H +++
Sbjct: 132 PNIPYVYIRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLHTIQDIN 186
>BC002354-1|AAH02354.1| 478|Homo sapiens 5-hydroxytryptamine
(serotonin) receptor 3A protein.
Length = 478
Score = 49.2 bits (112), Expect = 2e-05
Identities = 26/115 (22%), Positives = 51/115 (44%), Gaps = 1/115 (0%)
Frame = +3
Query: 231 NIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAG 407
N+ E + + W D+ L WN ++ T L + ++ +W PD+++
Sbjct: 72 NVDEKNQVLTTYIWYRQYWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKS 131
Query: 408 DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCAFKFGSRMHNSDEMD 572
+ + G V K L + T S+ + N+P D+Q C+ F S +H +++
Sbjct: 132 PNIPYVYIRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLHTIQDIN 186
>AJ005205-1|CAA06442.3| 478|Homo sapiens serotonin 3 receptor
protein.
Length = 478
Score = 49.2 bits (112), Expect = 2e-05
Identities = 26/115 (22%), Positives = 51/115 (44%), Gaps = 1/115 (0%)
Frame = +3
Query: 231 NIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAG 407
N+ E + + W D+ L WN ++ T L + ++ +W PD+++
Sbjct: 72 NVDEKNQVLTTYIWYRQYWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKS 131
Query: 408 DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCAFKFGSRMHNSDEMD 572
+ + G V K L + T S+ + N+P D+Q C+ F S +H +++
Sbjct: 132 PNIPYVYIRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLHTIQDIN 186
>AJ003079-1|CAA05852.1| 478|Homo sapiens 5-hydroxytryptamine3
receptor protein.
Length = 478
Score = 49.2 bits (112), Expect = 2e-05
Identities = 26/115 (22%), Positives = 51/115 (44%), Gaps = 1/115 (0%)
Frame = +3
Query: 231 NIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAG 407
N+ E + + W D+ L WN ++ T L + ++ +W PD+++
Sbjct: 72 NVDEKNQVLTTYIWYRQYWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKS 131
Query: 408 DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCAFKFGSRMHNSDEMD 572
+ + G V K L + T S+ + N+P D+Q C+ F S +H +++
Sbjct: 132 PNIPYVYIRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLHTIQDIN 186
>AJ003078-1|CAA05851.1| 510|Homo sapiens serotonin receptor
protein.
Length = 510
Score = 49.2 bits (112), Expect = 2e-05
Identities = 26/115 (22%), Positives = 51/115 (44%), Gaps = 1/115 (0%)
Frame = +3
Query: 231 NIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAG 407
N+ E + + W D+ L WN ++ T L + ++ +W PD+++
Sbjct: 72 NVDEKNQVLTTYIWYRQYWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKS 131
Query: 408 DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCAFKFGSRMHNSDEMD 572
+ + G V K L + T S+ + N+P D+Q C+ F S +H +++
Sbjct: 132 PNIPYVYIRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLHTIQDIN 186
>AF498984-1|AAM21131.1| 478|Homo sapiens 5-hydroxytryptamine
receptor 3A protein.
Length = 478
Score = 49.2 bits (112), Expect = 2e-05
Identities = 26/115 (22%), Positives = 51/115 (44%), Gaps = 1/115 (0%)
Frame = +3
Query: 231 NIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAG 407
N+ E + + W D+ L WN ++ T L + ++ +W PD+++
Sbjct: 72 NVDEKNQVLTTYIWYRQYWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKS 131
Query: 408 DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCAFKFGSRMHNSDEMD 572
+ + G V K L + T S+ + N+P D+Q C+ F S +H +++
Sbjct: 132 PNIPYVYIRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLHTIQDIN 186
>U30461-1|AAB52519.1| 554|Homo sapiens GABAA receptor subunit
alpha4 protein.
Length = 554
Score = 48.8 bits (111), Expect = 3e-05
Identities = 38/151 (25%), Positives = 66/151 (43%), Gaps = 8/151 (5%)
Frame = +3
Query: 141 MIDSLLATYD-RDSP----PDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLS 305
++DSLL YD R P P +++ ++ + + + E + + WIDKRL
Sbjct: 51 ILDSLLDGYDNRLRPGFGGPVTEVKTDIYV-TSFGPVSDVEMEYTMDVFFRQTWIDKRLK 109
Query: 306 WNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRA---RVSNNGSVSWIKRLDIS 476
++ + ++W PD N + + + R+ NG++ + RL IS
Sbjct: 110 YDGPIEILRLNNMMVTKVWTPDTFFRNGKKSVSHNMTAPNKLFRIMRNGTILYTMRLTIS 169
Query: 477 TPISMQLDNWPNDMQTCAFKFGSRMHNSDEM 569
M+L ++P D C KFGS + EM
Sbjct: 170 AECPMRLVDFPMDGHACPLKFGSYAYPKSEM 200
>BC035055-1|AAH35055.1| 554|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 4 protein.
Length = 554
Score = 48.8 bits (111), Expect = 3e-05
Identities = 38/151 (25%), Positives = 66/151 (43%), Gaps = 8/151 (5%)
Frame = +3
Query: 141 MIDSLLATYD-RDSP----PDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLS 305
++DSLL YD R P P +++ ++ + + + E + + WIDKRL
Sbjct: 51 ILDSLLDGYDNRLRPGFGGPVTEVKTDIYV-TSFGPVSDVEMEYTMDVFFRQTWIDKRLK 109
Query: 306 WNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRA---RVSNNGSVSWIKRLDIS 476
++ + ++W PD N + + + R+ NG++ + RL IS
Sbjct: 110 YDGPIEILRLNNMMVTKVWTPDTFFRNGKKSVSHNMTAPNKLFRIMRNGTILYTMRLTIS 169
Query: 477 TPISMQLDNWPNDMQTCAFKFGSRMHNSDEM 569
M+L ++P D C KFGS + EM
Sbjct: 170 AECPMRLVDFPMDGHACPLKFGSYAYPKSEM 200
>U77731-2|AAB38273.1| 360|Homo sapiens glycine receptor alpha 2B
subunit protein.
Length = 360
Score = 48.4 bits (110), Expect = 3e-05
Identities = 33/135 (24%), Positives = 59/135 (43%), Gaps = 4/135 (2%)
Frame = +3
Query: 183 PDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERL 359
P + N+ ++ +I E+ R+ L+ W D RL+++ S + +
Sbjct: 69 PPVNVTCNIFIN-SFGSIAETTMDYRVNIFLRQQWNDSRLAYSEYPDDSLDLDPSMLDSI 127
Query: 360 WRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCA 530
W+PD+ N D R+S NG V + RL ++ M L N+P D+QTC
Sbjct: 128 WKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNFPMDVQTCT 187
Query: 531 FKFGSRMHNSDEMDF 575
+ S + +++ F
Sbjct: 188 MQLESFGYTMNDLIF 202
>CR450343-1|CAG29339.1| 452|Homo sapiens GLRA2 protein.
Length = 452
Score = 48.4 bits (110), Expect = 3e-05
Identities = 33/135 (24%), Positives = 59/135 (43%), Gaps = 4/135 (2%)
Frame = +3
Query: 183 PDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERL 359
P + N+ ++ +I E+ R+ L+ W D RL+++ S + +
Sbjct: 69 PPVNVTCNIFIN-SFGSIAETTMDYRVNIFLRQQWNDSRLAYSEYPDDSLDLDPSMLDSI 127
Query: 360 WRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCA 530
W+PD+ N D R+S NG V + RL ++ M L N+P D+QTC
Sbjct: 128 WKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNFPMDVQTCT 187
Query: 531 FKFGSRMHNSDEMDF 575
+ S + +++ F
Sbjct: 188 MQLESFGYTMNDLIF 202
>AY437084-1|AAR87843.1| 452|Homo sapiens glycine receptor alpha2
subunit B protein.
Length = 452
Score = 48.4 bits (110), Expect = 3e-05
Identities = 33/135 (24%), Positives = 59/135 (43%), Gaps = 4/135 (2%)
Frame = +3
Query: 183 PDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERL 359
P + N+ ++ +I E+ R+ L+ W D RL+++ S + +
Sbjct: 69 PPVNVTCNIFIN-SFGSIAETTMDYRVNIFLRQQWNDSRLAYSEYPDDSLDLDPSMLDSI 127
Query: 360 WRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCA 530
W+PD+ N D R+S NG V + RL ++ M L N+P D+QTC
Sbjct: 128 WKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNFPMDVQTCT 187
Query: 531 FKFGSRMHNSDEMDF 575
+ S + +++ F
Sbjct: 188 MQLESFGYTMNDLIF 202
>X52008-1|CAA36257.1| 452|Homo sapiens inhibitory glycine receptor
protein.
Length = 452
Score = 48.0 bits (109), Expect = 4e-05
Identities = 32/135 (23%), Positives = 59/135 (43%), Gaps = 4/135 (2%)
Frame = +3
Query: 183 PDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERL 359
P + N+ ++ ++ E+ R+ L+ W D RL+++ S + +
Sbjct: 69 PPVNVTCNIFIN-SFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPDDSLDLDPSMLDSI 127
Query: 360 WRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCA 530
W+PD+ N D R+S NG V + RL ++ M L N+P D+QTC
Sbjct: 128 WKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNFPMDVQTCT 187
Query: 531 FKFGSRMHNSDEMDF 575
+ S + +++ F
Sbjct: 188 MQLESFGYTMNDLIF 202
>U77731-1|AAB38272.1| 360|Homo sapiens glycine receptor alpha 2
subunit protein.
Length = 360
Score = 48.0 bits (109), Expect = 4e-05
Identities = 32/135 (23%), Positives = 59/135 (43%), Gaps = 4/135 (2%)
Frame = +3
Query: 183 PDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERL 359
P + N+ ++ ++ E+ R+ L+ W D RL+++ S + +
Sbjct: 69 PPVNVTCNIFIN-SFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPDDSLDLDPSMLDSI 127
Query: 360 WRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCA 530
W+PD+ N D R+S NG V + RL ++ M L N+P D+QTC
Sbjct: 128 WKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNFPMDVQTCT 187
Query: 531 FKFGSRMHNSDEMDF 575
+ S + +++ F
Sbjct: 188 MQLESFGYTMNDLIF 202
>BC032864-1|AAH32864.1| 452|Homo sapiens glycine receptor, alpha 2
protein.
Length = 452
Score = 48.0 bits (109), Expect = 4e-05
Identities = 32/135 (23%), Positives = 59/135 (43%), Gaps = 4/135 (2%)
Frame = +3
Query: 183 PDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERL 359
P + N+ ++ ++ E+ R+ L+ W D RL+++ S + +
Sbjct: 69 PPVNVTCNIFIN-SFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPDDSLDLDPSMLDSI 127
Query: 360 WRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCA 530
W+PD+ N D R+S NG V + RL ++ M L N+P D+QTC
Sbjct: 128 WKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNFPMDVQTCT 187
Query: 531 FKFGSRMHNSDEMDF 575
+ S + +++ F
Sbjct: 188 MQLESFGYTMNDLIF 202
>AY437083-1|AAR87842.1| 452|Homo sapiens glycine receptor alpha2
subunit A protein.
Length = 452
Score = 48.0 bits (109), Expect = 4e-05
Identities = 32/135 (23%), Positives = 59/135 (43%), Gaps = 4/135 (2%)
Frame = +3
Query: 183 PDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERL 359
P + N+ ++ ++ E+ R+ L+ W D RL+++ S + +
Sbjct: 69 PPVNVTCNIFIN-SFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPDDSLDLDPSMLDSI 127
Query: 360 WRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCA 530
W+PD+ N D R+S NG V + RL ++ M L N+P D+QTC
Sbjct: 128 WKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNFPMDVQTCT 187
Query: 531 FKFGSRMHNSDEMDF 575
+ S + +++ F
Sbjct: 188 MQLESFGYTMNDLIF 202
>AF053495-1|AAC35290.1| 452|Homo sapiens glycine receptor alpha 2
subunit protein.
Length = 452
Score = 48.0 bits (109), Expect = 4e-05
Identities = 32/135 (23%), Positives = 59/135 (43%), Gaps = 4/135 (2%)
Frame = +3
Query: 183 PDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERL 359
P + N+ ++ ++ E+ R+ L+ W D RL+++ S + +
Sbjct: 69 PPVNVTCNIFIN-SFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPDDSLDLDPSMLDSI 127
Query: 360 WRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCA 530
W+PD+ N D R+S NG V + RL ++ M L N+P D+QTC
Sbjct: 128 WKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNFPMDVQTCT 187
Query: 531 FKFGSRMHNSDEMDF 575
+ S + +++ F
Sbjct: 188 MQLESFGYTMNDLIF 202
>BC096083-1|AAH96083.1| 198|Homo sapiens CHRNB4 protein protein.
Length = 198
Score = 47.6 bits (108), Expect = 6e-05
Identities = 30/115 (26%), Positives = 55/115 (47%), Gaps = 8/115 (6%)
Frame = +3
Query: 93 AIASAAECENATSLSLMIDSLL--ATYD---RDSPPDSKIV-VNLTLHLRHA-NIRESES 251
A+ C A + ++D LL Y+ R + S+++ + L L L ++ E E
Sbjct: 14 ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQ 73
Query: 252 TVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDY 413
+ L+ W D RL+WN+ + G + + ++R+W PD+VL N + T +
Sbjct: 74 IMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNKSLRTGSTW 128
>BC096081-1|AAH96081.1| 198|Homo sapiens CHRNB4 protein protein.
Length = 198
Score = 47.6 bits (108), Expect = 6e-05
Identities = 30/115 (26%), Positives = 55/115 (47%), Gaps = 8/115 (6%)
Frame = +3
Query: 93 AIASAAECENATSLSLMIDSLL--ATYD---RDSPPDSKIV-VNLTLHLRHA-NIRESES 251
A+ C A + ++D LL Y+ R + S+++ + L L L ++ E E
Sbjct: 14 ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQ 73
Query: 252 TVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDY 413
+ L+ W D RL+WN+ + G + + ++R+W PD+VL N + T +
Sbjct: 74 IMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNKSLRTGSTW 128
>BC033801-1|AAH33801.1| 452|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, delta protein.
Length = 452
Score = 47.2 bits (107), Expect = 8e-05
Identities = 38/149 (25%), Positives = 65/149 (43%), Gaps = 7/149 (4%)
Frame = +3
Query: 144 IDSLLATYDRDSPPD-SKIVVNLTLHLRHANI---RESESTVRIQADLQMNWIDKRLSWN 311
+D L+A Y R+ P VN+ L L A+I E+ + L +W D RLS+N
Sbjct: 44 LDGLIAGYARNFRPGIGGPPVNVALALEVASIDHISEANMEYTMTVFLHQSWRDSRLSYN 103
Query: 312 AGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTP 482
++LW PD ++NA + D + R+ +G + + R+ +
Sbjct: 104 HTNETLGLDSRFVDKLWLPDTFIVNAKSAWFHDVTVENKLIRLQPDGVILYSIRITSTVA 163
Query: 483 ISMQLDNWPNDMQTCAFKFGSRMHNSDEM 569
M L +P D Q C S ++S+++
Sbjct: 164 CDMDLAKYPMDEQECMLDLESYGYSSEDI 192
>AL391845-4|CAI15436.1| 452|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, delta protein.
Length = 452
Score = 47.2 bits (107), Expect = 8e-05
Identities = 38/149 (25%), Positives = 65/149 (43%), Gaps = 7/149 (4%)
Frame = +3
Query: 144 IDSLLATYDRDSPPD-SKIVVNLTLHLRHANI---RESESTVRIQADLQMNWIDKRLSWN 311
+D L+A Y R+ P VN+ L L A+I E+ + L +W D RLS+N
Sbjct: 44 LDGLIAGYARNFRPGIGGPPVNVALALEVASIDHISEANMEYTMTVFLHQSWRDSRLSYN 103
Query: 312 AGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTP 482
++LW PD ++NA + D + R+ +G + + R+ +
Sbjct: 104 HTNETLGLDSRFVDKLWLPDTFIVNAKSAWFHDVTVENKLIRLQPDGVILYSIRITSTVA 163
Query: 483 ISMQLDNWPNDMQTCAFKFGSRMHNSDEM 569
M L +P D Q C S ++S+++
Sbjct: 164 CDMDLAKYPMDEQECMLDLESYGYSSEDI 192
>AF016917-1|AAB70007.1| 452|Homo sapiens GABA-A receptor delta
subunit protein.
Length = 452
Score = 47.2 bits (107), Expect = 8e-05
Identities = 38/149 (25%), Positives = 65/149 (43%), Gaps = 7/149 (4%)
Frame = +3
Query: 144 IDSLLATYDRDSPPD-SKIVVNLTLHLRHANI---RESESTVRIQADLQMNWIDKRLSWN 311
+D L+A Y R+ P VN+ L L A+I E+ + L +W D RLS+N
Sbjct: 44 LDGLIAGYARNFRPGIGGPPVNVALALEVASIDHISEANMEYTMTVFLHQSWRDSRLSYN 103
Query: 312 AGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTP 482
++LW PD ++NA + D + R+ +G + + R+ +
Sbjct: 104 HTNETLGLDSRFVDKLWLPDTFIVNAKSAWFHDVTVENKLIRLQPDGVILYSIRITSTVA 163
Query: 483 ISMQLDNWPNDMQTCAFKFGSRMHNSDEM 569
M L +P D Q C S ++S+++
Sbjct: 164 CDMDLAKYPMDEQECMLDLESYGYSSEDI 192
>U95367-1|AAC51357.1| 440|Homo sapiens GABA-A receptor pi subunit
protein.
Length = 440
Score = 46.8 bits (106), Expect = 1e-04
Identities = 40/164 (24%), Positives = 78/164 (47%), Gaps = 9/164 (5%)
Frame = +3
Query: 111 ECENATSLSLM-IDSLLATYDRDSPPD---SKIVVNLTLHLRH-ANIRESESTVRIQADL 275
E + LSL ++L A Y++ P+ + + LTL + ++I ES L
Sbjct: 29 EVGRSDKLSLPGFENLTAGYNKFLRPNFGGEPVQIALTLDIASISSISESNMDYTATIYL 88
Query: 276 QMNWIDKRLSWNAGE-WGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNG 443
+ W+D+RL + + + LV E LW PD ++ + + + + R+ +NG
Sbjct: 89 RQRWMDQRLVFEGNKSFTLDARLV--EFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNG 146
Query: 444 SVSWIKRLDISTPISMQLDNWPNDMQTCAFKFGSRMHNSDEMDF 575
+V + R+ + +M L +P D QTC + S ++ ++++F
Sbjct: 147 TVLYALRITTTVACNMDLSKYPMDTQTCKLQLESWGYDGNDVEF 190
>BC109106-1|AAI09107.1| 440|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, pi protein.
Length = 440
Score = 46.8 bits (106), Expect = 1e-04
Identities = 40/164 (24%), Positives = 78/164 (47%), Gaps = 9/164 (5%)
Frame = +3
Query: 111 ECENATSLSLM-IDSLLATYDRDSPPD---SKIVVNLTLHLRH-ANIRESESTVRIQADL 275
E + LSL ++L A Y++ P+ + + LTL + ++I ES L
Sbjct: 29 EVGRSDKLSLPGFENLTAGYNKFLRPNFGGEPVQIALTLDIASISSISESNMDYTATIYL 88
Query: 276 QMNWIDKRLSWNAGE-WGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNG 443
+ W+D+RL + + + LV E LW PD ++ + + + + R+ +NG
Sbjct: 89 RQRWMDQRLVFEGNKSFTLDARLV--EFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNG 146
Query: 444 SVSWIKRLDISTPISMQLDNWPNDMQTCAFKFGSRMHNSDEMDF 575
+V + R+ + +M L +P D QTC + S ++ ++++F
Sbjct: 147 TVLYALRITTTVACNMDLSKYPMDTQTCKLQLESWGYDGNDVEF 190
>BC109105-1|AAI09106.1| 440|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, pi protein.
Length = 440
Score = 46.8 bits (106), Expect = 1e-04
Identities = 40/164 (24%), Positives = 78/164 (47%), Gaps = 9/164 (5%)
Frame = +3
Query: 111 ECENATSLSLM-IDSLLATYDRDSPPD---SKIVVNLTLHLRH-ANIRESESTVRIQADL 275
E + LSL ++L A Y++ P+ + + LTL + ++I ES L
Sbjct: 29 EVGRSDKLSLPGFENLTAGYNKFLRPNFGGEPVQIALTLDIASISSISESNMDYTATIYL 88
Query: 276 QMNWIDKRLSWNAGE-WGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNG 443
+ W+D+RL + + + LV E LW PD ++ + + + + R+ +NG
Sbjct: 89 RQRWMDQRLVFEGNKSFTLDARLV--EFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNG 146
Query: 444 SVSWIKRLDISTPISMQLDNWPNDMQTCAFKFGSRMHNSDEMDF 575
+V + R+ + +M L +P D QTC + S ++ ++++F
Sbjct: 147 TVLYALRITTTVACNMDLSKYPMDTQTCKLQLESWGYDGNDVEF 190
>BC074865-1|AAH74865.1| 440|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, pi protein.
Length = 440
Score = 46.8 bits (106), Expect = 1e-04
Identities = 40/164 (24%), Positives = 78/164 (47%), Gaps = 9/164 (5%)
Frame = +3
Query: 111 ECENATSLSLM-IDSLLATYDRDSPPD---SKIVVNLTLHLRH-ANIRESESTVRIQADL 275
E + LSL ++L A Y++ P+ + + LTL + ++I ES L
Sbjct: 29 EVGRSDKLSLPGFENLTAGYNKFLRPNFGGEPVQIALTLDIASISSISESNMDYTATIYL 88
Query: 276 QMNWIDKRLSWNAGE-WGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNG 443
+ W+D+RL + + + LV E LW PD ++ + + + + R+ +NG
Sbjct: 89 RQRWMDQRLVFEGNKSFTLDARLV--EFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNG 146
Query: 444 SVSWIKRLDISTPISMQLDNWPNDMQTCAFKFGSRMHNSDEMDF 575
+V + R+ + +M L +P D QTC + S ++ ++++F
Sbjct: 147 TVLYALRITTTVACNMDLSKYPMDTQTCKLQLESWGYDGNDVEF 190
>BC074810-1|AAH74810.1| 440|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, pi protein.
Length = 440
Score = 46.8 bits (106), Expect = 1e-04
Identities = 40/164 (24%), Positives = 78/164 (47%), Gaps = 9/164 (5%)
Frame = +3
Query: 111 ECENATSLSLM-IDSLLATYDRDSPPD---SKIVVNLTLHLRH-ANIRESESTVRIQADL 275
E + LSL ++L A Y++ P+ + + LTL + ++I ES L
Sbjct: 29 EVGRSDKLSLPGFENLTAGYNKFLRPNFGGEPVQIALTLDIASISSISESNMDYTATIYL 88
Query: 276 QMNWIDKRLSWNAGE-WGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNG 443
+ W+D+RL + + + LV E LW PD ++ + + + + R+ +NG
Sbjct: 89 RQRWMDQRLVFEGNKSFTLDARLV--EFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNG 146
Query: 444 SVSWIKRLDISTPISMQLDNWPNDMQTCAFKFGSRMHNSDEMDF 575
+V + R+ + +M L +P D QTC + S ++ ++++F
Sbjct: 147 TVLYALRITTTVACNMDLSKYPMDTQTCKLQLESWGYDGNDVEF 190
>AF009702-1|AAC24194.1| 440|Homo sapiens GABA-A receptor pi subunit
protein.
Length = 440
Score = 46.8 bits (106), Expect = 1e-04
Identities = 40/164 (24%), Positives = 78/164 (47%), Gaps = 9/164 (5%)
Frame = +3
Query: 111 ECENATSLSLM-IDSLLATYDRDSPPD---SKIVVNLTLHLRH-ANIRESESTVRIQADL 275
E + LSL ++L A Y++ P+ + + LTL + ++I ES L
Sbjct: 29 EVGRSDKLSLPGFENLTAGYNKFLRPNFGGEPVQIALTLDIASISSISESNMDYTATIYL 88
Query: 276 QMNWIDKRLSWNAGE-WGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNG 443
+ W+D+RL + + + LV E LW PD ++ + + + + R+ +NG
Sbjct: 89 RQRWMDQRLVFEGNKSFTLDARLV--EFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNG 146
Query: 444 SVSWIKRLDISTPISMQLDNWPNDMQTCAFKFGSRMHNSDEMDF 575
+V + R+ + +M L +P D QTC + S ++ ++++F
Sbjct: 147 TVLYALRITTTVACNMDLSKYPMDTQTCKLQLESWGYDGNDVEF 190
>X52009-1|CAA36258.1| 449|Homo sapiens inhibitory glycine receptor
protein.
Length = 449
Score = 46.0 bits (104), Expect = 2e-04
Identities = 30/119 (25%), Positives = 54/119 (45%), Gaps = 4/119 (3%)
Frame = +3
Query: 231 NIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERLWRPDVVLLNAAATTAG 407
+I E+ R+ L+ W D RL++N S + +W+PD+ N
Sbjct: 78 SIAETTMDYRVNIFLRQQWNDPRLAYNEYPDDSLDLDPSMLDSIWKPDLFFANEKGAHFH 137
Query: 408 DYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCAFKFGSRMHNSDEMDF 575
+ R+S NG+V + R+ ++ M L N+P D+QTC + S + +++ F
Sbjct: 138 EITTDNKLLRISRNGNVLYSIRITLTLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIF 196
>BC114947-1|AAI14948.1| 457|Homo sapiens GLRA1 protein protein.
Length = 457
Score = 46.0 bits (104), Expect = 2e-04
Identities = 30/119 (25%), Positives = 54/119 (45%), Gaps = 4/119 (3%)
Frame = +3
Query: 231 NIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERLWRPDVVLLNAAATTAG 407
+I E+ R+ L+ W D RL++N S + +W+PD+ N
Sbjct: 78 SIAETTMDYRVNIFLRQQWNDPRLAYNEYPDDSLDLDPSMLDSIWKPDLFFANEKGAHFH 137
Query: 408 DYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCAFKFGSRMHNSDEMDF 575
+ R+S NG+V + R+ ++ M L N+P D+QTC + S + +++ F
Sbjct: 138 EITTDNKLLRISRNGNVLYSIRITLTLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIF 196
>BC109211-1|AAI09212.1| 632|Homo sapiens gamma-aminobutyric acid
(GABA) receptor, theta protein.
Length = 632
Score = 46.0 bits (104), Expect = 2e-04
Identities = 35/145 (24%), Positives = 60/145 (41%), Gaps = 7/145 (4%)
Frame = +3
Query: 114 CENATSLSLMIDSLLATYDRDSPPD---SKIVVNLTLHLRHAN-IRESESTVRIQADLQM 281
C N + ++D +L+ YD P+ + + V +++++ I E I
Sbjct: 53 CANEAVVQKILDRVLSRYDVRLRPNFGGAPVPVRISIYVTSIEQISEMNMDYTITMFFHQ 112
Query: 282 NWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSN---NGSVS 452
W D RL++ + E+LW PD LN+ D + RV +G+V
Sbjct: 113 TWKDSRLAYYETTLNLTLDYRMHEKLWVPDCYFLNSKDAFVHDVTVENRVFQLHPDGTVR 172
Query: 453 WIKRLDISTPISMQLDNWPNDMQTC 527
+ RL + S+ L +P D Q C
Sbjct: 173 YGIRLTTTAACSLDLHKFPMDKQAC 197
>BC109210-1|AAI09211.1| 632|Homo sapiens gamma-aminobutyric acid
(GABA) receptor, theta protein.
Length = 632
Score = 46.0 bits (104), Expect = 2e-04
Identities = 35/145 (24%), Positives = 60/145 (41%), Gaps = 7/145 (4%)
Frame = +3
Query: 114 CENATSLSLMIDSLLATYDRDSPPD---SKIVVNLTLHLRHAN-IRESESTVRIQADLQM 281
C N + ++D +L+ YD P+ + + V +++++ I E I
Sbjct: 53 CANEAVVQKILDRVLSRYDVRLRPNFGGAPVPVRISIYVTSIEQISEMNMDYTITMFFHQ 112
Query: 282 NWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSN---NGSVS 452
W D RL++ + E+LW PD LN+ D + RV +G+V
Sbjct: 113 TWKDSRLAYYETTLNLTLDYRMHEKLWVPDCYFLNSKDAFVHDVTVENRVFQLHPDGTVR 172
Query: 453 WIKRLDISTPISMQLDNWPNDMQTC 527
+ RL + S+ L +P D Q C
Sbjct: 173 YGIRLTTTAACSLDLHKFPMDKQAC 197
>BC074980-1|AAH74980.1| 449|Homo sapiens glycine receptor, alpha 1
(startle disease/hyperekplexia) protein.
Length = 449
Score = 46.0 bits (104), Expect = 2e-04
Identities = 30/119 (25%), Positives = 54/119 (45%), Gaps = 4/119 (3%)
Frame = +3
Query: 231 NIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERLWRPDVVLLNAAATTAG 407
+I E+ R+ L+ W D RL++N S + +W+PD+ N
Sbjct: 78 SIAETTMDYRVNIFLRQQWNDPRLAYNEYPDDSLDLDPSMLDSIWKPDLFFANEKGAHFH 137
Query: 408 DYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCAFKFGSRMHNSDEMDF 575
+ R+S NG+V + R+ ++ M L N+P D+QTC + S + +++ F
Sbjct: 138 EITTDNKLLRISRNGNVLYSIRITLTLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIF 196
>AF189259-1|AAF70380.1| 632|Homo sapiens GABA-A receptor theta
subunit protein.
Length = 632
Score = 46.0 bits (104), Expect = 2e-04
Identities = 35/145 (24%), Positives = 60/145 (41%), Gaps = 7/145 (4%)
Frame = +3
Query: 114 CENATSLSLMIDSLLATYDRDSPPD---SKIVVNLTLHLRHAN-IRESESTVRIQADLQM 281
C N + ++D +L+ YD P+ + + V +++++ I E I
Sbjct: 53 CANEAVVQKILDRVLSRYDVRLRPNFGGAPVPVRISIYVTSIEQISEMNMDYTITMFFHQ 112
Query: 282 NWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSN---NGSVS 452
W D RL++ + E+LW PD LN+ D + RV +G+V
Sbjct: 113 TWKDSRLAYYETTLNLTLDYRMHEKLWVPDCYFLNSKDAFVHDVTVENRVFQLHPDGTVR 172
Query: 453 WIKRLDISTPISMQLDNWPNDMQTC 527
+ RL + S+ L +P D Q C
Sbjct: 173 YGIRLTTTAACSLDLHKFPMDKQAC 197
>AF144648-1|AAD51172.1| 627|Homo sapiens GABA-A receptor theta
protein.
Length = 627
Score = 46.0 bits (104), Expect = 2e-04
Identities = 35/145 (24%), Positives = 60/145 (41%), Gaps = 7/145 (4%)
Frame = +3
Query: 114 CENATSLSLMIDSLLATYDRDSPPD---SKIVVNLTLHLRHAN-IRESESTVRIQADLQM 281
C N + ++D +L+ YD P+ + + V +++++ I E I
Sbjct: 48 CANEAVVQKILDRVLSRYDVRLRPNFGGAPVPVRISIYVTSIEQISEMNMDYTITMFFHQ 107
Query: 282 NWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSN---NGSVS 452
W D RL++ + E+LW PD LN+ D + RV +G+V
Sbjct: 108 TWKDSRLAYYETTLNLTLDYRMHEKLWVPDCYFLNSKDAFVHDVTVENRVFQLHPDGTVR 167
Query: 453 WIKRLDISTPISMQLDNWPNDMQTC 527
+ RL + S+ L +P D Q C
Sbjct: 168 YGIRLTTTAACSLDLHKFPMDKQAC 192
>BC022449-1|AAH22449.1| 474|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, beta 1 protein.
Length = 474
Score = 45.6 bits (103), Expect = 2e-04
Identities = 38/171 (22%), Positives = 72/171 (42%), Gaps = 7/171 (4%)
Frame = +3
Query: 84 LTCAIASAAECENATSLSLMIDSLLATYDRDSPPD---SKIVVNLTLHLRHAN-IRESES 251
+ C S E N + + +D LL YD PD + V + + + + + E
Sbjct: 21 MVCCAHSTNEPSNMSYVKETVDRLLKGYDIRLRPDFGGPPVDVGMRIDVASIDMVSEVNM 80
Query: 252 TVRIQADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR--- 422
+ Q +W DKRLS++ + +++L PD LN + ++
Sbjct: 81 DYTLTMYFQQSWKDKRLSYSGIPLNLTLDNRVADQLCVPDTYFLNDKKSFVHGVTVKNRM 140
Query: 423 ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCAFKFGSRMHNSDEMDF 575
R+ +G+V + R+ + M L +P D Q C + S + +D+++F
Sbjct: 141 IRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEF 191
>BC031087-1|AAH31087.1| 465|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, gamma 1 protein.
Length = 465
Score = 44.4 bits (100), Expect = 5e-04
Identities = 35/155 (22%), Positives = 65/155 (41%), Gaps = 7/155 (4%)
Frame = +3
Query: 132 LSLMIDSLLATYDRDSPPDSKI---VVNLTLHLRHAN-IRESESTVRIQADLQMNWIDKR 299
++ +++SLL YD PD + V+ +++ + I W D R
Sbjct: 64 ITQILNSLLQGYDNKLRPDIGVRPTVIETDVYVNSIGPVDPINMEYTIDIIFAQTWFDSR 123
Query: 300 LSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLD 470
L +N+ ++W PD N+ + A R+ N+G V + RL
Sbjct: 124 LKFNSTMKVLMLNSNMVGKIWIPDTFFRNSRKSDAHWITTPNRLLRIWNDGRVLYTLRLT 183
Query: 471 ISTPISMQLDNWPNDMQTCAFKFGSRMHNSDEMDF 575
I+ +QL N+P D +C +F S + +E+++
Sbjct: 184 INAECYLQLHNFPMDEHSCPLEFSSYGYPKNEIEY 218
>U93917-1|AAC39917.1| 449|Homo sapiens glycine receptor alpha 3
subunit protein.
Length = 449
Score = 44.0 bits (99), Expect = 7e-04
Identities = 31/135 (22%), Positives = 59/135 (43%), Gaps = 4/135 (2%)
Frame = +3
Query: 183 PDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERL 359
P + N+ ++ +I E+ R+ L+ W D RL+++ S + +
Sbjct: 68 PPVNVTCNIFIN-SFGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPDDSLDLDPSMLDSI 126
Query: 360 WRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCA 530
W+PD+ N + R+ NG+V + RL ++ M L N+P D+QTC
Sbjct: 127 WKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFPMDVQTCI 186
Query: 531 FKFGSRMHNSDEMDF 575
+ S + +++ F
Sbjct: 187 MQLESFGYTMNDLIF 201
>BC036086-1|AAH36086.1| 464|Homo sapiens glycine receptor, alpha 3
protein.
Length = 464
Score = 44.0 bits (99), Expect = 7e-04
Identities = 31/135 (22%), Positives = 59/135 (43%), Gaps = 4/135 (2%)
Frame = +3
Query: 183 PDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERL 359
P + N+ ++ +I E+ R+ L+ W D RL+++ S + +
Sbjct: 68 PPVNVTCNIFIN-SFGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPDDSLDLDPSMLDSI 126
Query: 360 WRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCA 530
W+PD+ N + R+ NG+V + RL ++ M L N+P D+QTC
Sbjct: 127 WKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFPMDVQTCI 186
Query: 531 FKFGSRMHNSDEMDF 575
+ S + +++ F
Sbjct: 187 MQLESFGYTMNDLIF 201
>AF017724-1|AAC39919.1| 465|Homo sapiens glycine receptor alpha 3
subunit protein.
Length = 465
Score = 44.0 bits (99), Expect = 7e-04
Identities = 31/135 (22%), Positives = 59/135 (43%), Gaps = 4/135 (2%)
Frame = +3
Query: 183 PDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERL 359
P + N+ ++ +I E+ R+ L+ W D RL+++ S + +
Sbjct: 68 PPVNVTCNIFIN-SFGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPDDSLDLDPSMLDSI 126
Query: 360 WRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCA 530
W+PD+ N + R+ NG+V + RL ++ M L N+P D+QTC
Sbjct: 127 WKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFPMDVQTCI 186
Query: 531 FKFGSRMHNSDEMDF 575
+ S + +++ F
Sbjct: 187 MQLESFGYTMNDLIF 201
>BC114967-1|AAI14968.1| 366|Homo sapiens GLRA1 protein protein.
Length = 366
Score = 43.6 bits (98), Expect = 0.001
Identities = 28/110 (25%), Positives = 50/110 (45%), Gaps = 4/110 (3%)
Frame = +3
Query: 258 RIQADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERLWRPDVVLLNAAATTAGDYALR---A 425
R+ L+ W D RL++N S + +W+PD+ N +
Sbjct: 4 RVNIFLRQQWNDPRLAYNEYPDDSLDLDPSMLDSIWKPDLFFANEKGAHFHEITTDNKLL 63
Query: 426 RVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCAFKFGSRMHNSDEMDF 575
R+S NG+V + R+ ++ M L N+P D+QTC + S + +++ F
Sbjct: 64 RISRNGNVLYSIRITLTLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIF 113
>BC074795-1|AAH74795.1| 467|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, gamma 2 protein.
Length = 467
Score = 43.6 bits (98), Expect = 0.001
Identities = 34/153 (22%), Positives = 65/153 (42%), Gaps = 7/153 (4%)
Frame = +3
Query: 132 LSLMIDSLLATYDRDSPPDSKIVVNLTLHLRHANIRESESTVRIQADLQM----NWIDKR 299
+++++++LL YD PD + L + N + + ++ + + W D+R
Sbjct: 66 VTVILNNLLEGYDNKLRPDIGVKPTLIHTDMYVNSIGPVNAINMEYTIDIFFAQTWYDRR 125
Query: 300 LSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYAL---RARVSNNGSVSWIKRLD 470
L +N+ ++W PD N+ A R+ N+G V + RL
Sbjct: 126 LKFNSTIKVLRLNSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYTLRLT 185
Query: 471 ISTPISMQLDNWPNDMQTCAFKFGSRMHNSDEM 569
I +QL N+P D +C +F S + +E+
Sbjct: 186 IDAECQLQLHNFPMDEHSCPLEFSSYGYPREEI 218
>BC069348-1|AAH69348.1| 467|Homo sapiens gamma-aminobutyric acid A
receptor, gamma 2, isoform 2 precursor protein.
Length = 467
Score = 43.6 bits (98), Expect = 0.001
Identities = 34/153 (22%), Positives = 65/153 (42%), Gaps = 7/153 (4%)
Frame = +3
Query: 132 LSLMIDSLLATYDRDSPPDSKIVVNLTLHLRHANIRESESTVRIQADLQM----NWIDKR 299
+++++++LL YD PD + L + N + + ++ + + W D+R
Sbjct: 66 VTVILNNLLEGYDNKLRPDIGVKPTLIHTDMYVNSIGPVNAINMEYTIDIFFAQTWYDRR 125
Query: 300 LSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYAL---RARVSNNGSVSWIKRLD 470
L +N+ ++W PD N+ A R+ N+G V + RL
Sbjct: 126 LKFNSTIKVLRLNSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYTLRLT 185
Query: 471 ISTPISMQLDNWPNDMQTCAFKFGSRMHNSDEM 569
I +QL N+P D +C +F S + +E+
Sbjct: 186 IDAECQLQLHNFPMDEHSCPLEFSSYGYPREEI 218
>BC059389-1|AAH59389.1| 475|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, gamma 2 protein.
Length = 475
Score = 43.6 bits (98), Expect = 0.001
Identities = 34/153 (22%), Positives = 65/153 (42%), Gaps = 7/153 (4%)
Frame = +3
Query: 132 LSLMIDSLLATYDRDSPPDSKIVVNLTLHLRHANIRESESTVRIQADLQM----NWIDKR 299
+++++++LL YD PD + L + N + + ++ + + W D+R
Sbjct: 66 VTVILNNLLEGYDNKLRPDIGVKPTLIHTDMYVNSIGPVNAINMEYTIDIFFAQTWYDRR 125
Query: 300 LSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYAL---RARVSNNGSVSWIKRLD 470
L +N+ ++W PD N+ A R+ N+G V + RL
Sbjct: 126 LKFNSTIKVLRLNSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYTLRLT 185
Query: 471 ISTPISMQLDNWPNDMQTCAFKFGSRMHNSDEM 569
I +QL N+P D +C +F S + +E+
Sbjct: 186 IDAECQLQLHNFPMDEHSCPLEFSSYGYPREEI 218
>AF165124-1|AAD50273.1| 467|Homo sapiens gamma-aminobutyric acid A
receptor gamma 2 protein.
Length = 467
Score = 43.6 bits (98), Expect = 0.001
Identities = 34/153 (22%), Positives = 65/153 (42%), Gaps = 7/153 (4%)
Frame = +3
Query: 132 LSLMIDSLLATYDRDSPPDSKIVVNLTLHLRHANIRESESTVRIQADLQM----NWIDKR 299
+++++++LL YD PD + L + N + + ++ + + W D+R
Sbjct: 66 VTVILNNLLEGYDNKLRPDIGVKPTLIHTDMYVNSIGPVNAINMEYTIDIFFAQTWYDRR 125
Query: 300 LSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYAL---RARVSNNGSVSWIKRLD 470
L +N+ ++W PD N+ A R+ N+G V + RL
Sbjct: 126 LKFNSTIKVLRLNSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYTLRLT 185
Query: 471 ISTPISMQLDNWPNDMQTCAFKFGSRMHNSDEM 569
I +QL N+P D +C +F S + +E+
Sbjct: 186 IDAECQLQLHNFPMDEHSCPLEFSSYGYPREEI 218
>X15376-1|CAA33437.1| 467|Homo sapiens GABA-A receptor gamma 2
subunit protein.
Length = 467
Score = 42.3 bits (95), Expect = 0.002
Identities = 34/153 (22%), Positives = 65/153 (42%), Gaps = 7/153 (4%)
Frame = +3
Query: 132 LSLMIDSLLATYDRDSPPDSKIVVNLTLHLRHANIRESESTVRIQADLQM----NWIDKR 299
+++++++LL YD PD + L + N + + ++ + + W D+R
Sbjct: 66 VTVILNNLLEGYDNKLRPDIGVKPTLIHTDMYVNSIGPVNAINMEYTIDIFFAQMWYDRR 125
Query: 300 LSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYAL---RARVSNNGSVSWIKRLD 470
L +N+ ++W PD N+ A R+ N+G V + RL
Sbjct: 126 LKFNSTIKVLRLNSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYSLRLT 185
Query: 471 ISTPISMQLDNWPNDMQTCAFKFGSRMHNSDEM 569
I +QL N+P D +C +F S + +E+
Sbjct: 186 IDAECQLQLHNFPMDEHSCPLEFSSYGYPREEI 218
>Z93848-1|CAI41994.1| 376|Homo sapiens glycine receptor, alpha 4
protein.
Length = 376
Score = 41.9 bits (94), Expect = 0.003
Identities = 31/135 (22%), Positives = 57/135 (42%), Gaps = 4/135 (2%)
Frame = +3
Query: 183 PDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERL 359
P + N+ ++ ++I ++ R+ L+ W D RLS+ S + +
Sbjct: 28 PPVNVTCNIFIN-SFSSITKTTMDYRVNVFLRQQWNDPRLSYREYPDDSLDLDPSMLDSI 86
Query: 360 WRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCA 530
W+PD+ N + R+ NG+V + RL + M L N+P D+QTC
Sbjct: 87 WKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLILSCLMDLKNFPMDIQTCT 146
Query: 531 FKFGSRMHNSDEMDF 575
+ S + ++ F
Sbjct: 147 MQLESFGYTMKDLVF 161
>AL049610-1|CAI42158.1| 376|Homo sapiens glycine receptor, alpha 4
protein.
Length = 376
Score = 41.9 bits (94), Expect = 0.003
Identities = 31/135 (22%), Positives = 57/135 (42%), Gaps = 4/135 (2%)
Frame = +3
Query: 183 PDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERL 359
P + N+ ++ ++I ++ R+ L+ W D RLS+ S + +
Sbjct: 28 PPVNVTCNIFIN-SFSSITKTTMDYRVNVFLRQQWNDPRLSYREYPDDSLDLDPSMLDSI 86
Query: 360 WRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCA 530
W+PD+ N + R+ NG+V + RL + M L N+P D+QTC
Sbjct: 87 WKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLILSCLMDLKNFPMDIQTCT 146
Query: 531 FKFGSRMHNSDEMDF 575
+ S + ++ F
Sbjct: 147 MQLESFGYTMKDLVF 161
>AB209359-1|BAD92596.1| 533|Homo sapiens cholinergic receptor,
nicotinic, alpha polypeptide 4 precursor variant
protein.
Length = 533
Score = 39.1 bits (87), Expect = 0.020
Identities = 24/91 (26%), Positives = 41/91 (45%), Gaps = 3/91 (3%)
Frame = +3
Query: 357 LWRPDVVLLNAAATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCAFK 536
LW +A A + +A + ++G V W + S+ + +P D Q C K
Sbjct: 25 LWLCCCTFTSADGDFAVTHLTKAHLFHDGRVQWTPPAIYKSSCSIDVTFFPFDQQNCTMK 84
Query: 537 FGSRMHNSDEMDFV-IDXRI--YSMFESGXW 620
FGS ++ ++D V + R+ +ESG W
Sbjct: 85 FGSWTYDKAKIDLVNMHSRVDQLDFWESGEW 115
>BC096291-1|AAH96291.1| 556|Homo sapiens CHRNA4 protein protein.
Length = 556
Score = 38.3 bits (85), Expect = 0.035
Identities = 23/79 (29%), Positives = 40/79 (50%), Gaps = 7/79 (8%)
Frame = +3
Query: 405 GDYAL----RARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCAFKFGSRMHNSDEMD 572
GD+A+ +A + ++G V W + S+ + +P D Q C KFGS ++ ++D
Sbjct: 60 GDFAVTHLTKAHLFHDGRVQWTPPAIYKSSCSIDVTFFPFDQQNCTMKFGSWTYDKAKID 119
Query: 573 FV-IDXRI--YSMFESGXW 620
V + R+ +ESG W
Sbjct: 120 LVNMHSRVDQLDFWESGEW 138
>U83981-1|AAC25631.1| 674|Homo sapiens apoptosis associated protein
protein.
Length = 674
Score = 31.1 bits (67), Expect = 5.4
Identities = 17/46 (36%), Positives = 22/46 (47%), Gaps = 1/46 (2%)
Frame = -2
Query: 432 IHGRGERSPRRWLQPRLAVPRQASTSVPRTPAKCCSP-TPLRSNSV 298
I+ GE+ P W PRL + Q P TP P TPL++ V
Sbjct: 511 IYVPGEKPPPPWAPPRLPLRLQRRLKRPETPTHDPDPETPLKARKV 556
>CR457259-1|CAG33540.1| 674|Homo sapiens PPP1R15A protein.
Length = 674
Score = 31.1 bits (67), Expect = 5.4
Identities = 17/46 (36%), Positives = 22/46 (47%), Gaps = 1/46 (2%)
Frame = -2
Query: 432 IHGRGERSPRRWLQPRLAVPRQASTSVPRTPAKCCSP-TPLRSNSV 298
I+ GE+ P W PRL + Q P TP P TPL++ V
Sbjct: 511 IYVPGEKPPPPWAPPRLPLRLQRRLKRPETPTHDPDPETPLKARKV 556
>BC003067-1|AAH03067.1| 674|Homo sapiens protein phosphatase 1,
regulatory (inhibitor) subunit 15A protein.
Length = 674
Score = 31.1 bits (67), Expect = 5.4
Identities = 17/46 (36%), Positives = 22/46 (47%), Gaps = 1/46 (2%)
Frame = -2
Query: 432 IHGRGERSPRRWLQPRLAVPRQASTSVPRTPAKCCSP-TPLRSNSV 298
I+ GE+ P W PRL + Q P TP P TPL++ V
Sbjct: 511 IYVPGEKPPPPWAPPRLPLRLQRRLKRPETPTHDPDPETPLKARKV 556
>AK001361-1|BAA91649.1| 674|Homo sapiens protein ( Homo sapiens
cDNA FLJ10499 fis, clone NT2RP2000346, weakly similar to
MYELOID DIFFERENTIATION PRIMARY RESPONSE PROTEIN MYD116.
).
Length = 674
Score = 31.1 bits (67), Expect = 5.4
Identities = 17/46 (36%), Positives = 22/46 (47%), Gaps = 1/46 (2%)
Frame = -2
Query: 432 IHGRGERSPRRWLQPRLAVPRQASTSVPRTPAKCCSP-TPLRSNSV 298
I+ GE+ P W PRL + Q P TP P TPL++ V
Sbjct: 511 IYVPGEKPPPPWAPPRLPLRLQRRLKRPETPTHDPDPETPLKARKV 556
>BC146774-1|AAI46775.1| 1114|Homo sapiens GPR124 protein protein.
Length = 1114
Score = 30.7 bits (66), Expect = 7.1
Identities = 16/55 (29%), Positives = 26/55 (47%), Gaps = 1/55 (1%)
Frame = +3
Query: 306 WNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNN-GSVSWIKRL 467
W +GEW C+ + + ++V+L T+ Y RV+NN G W + L
Sbjct: 314 WASGEWECTVSMAQGNASKKVEIVVLE----TSASYCPAERVANNRGDFRWPRTL 364
>AY181242-1|AAO27354.1| 1331|Homo sapiens G protein-coupled receptor
124 protein.
Length = 1331
Score = 30.7 bits (66), Expect = 7.1
Identities = 16/55 (29%), Positives = 26/55 (47%), Gaps = 1/55 (1%)
Frame = +3
Query: 306 WNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNN-GSVSWIKRL 467
W +GEW C+ + + ++V+L T+ Y RV+NN G W + L
Sbjct: 314 WASGEWECTVSMAQGNASKKVEIVVLE----TSASYCPAERVANNRGDFRWPRTL 364
>AK074099-1|BAB84925.1| 1310|Homo sapiens FLJ00170 protein protein.
Length = 1310
Score = 30.7 bits (66), Expect = 7.1
Identities = 16/55 (29%), Positives = 26/55 (47%), Gaps = 1/55 (1%)
Frame = +3
Query: 306 WNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNN-GSVSWIKRL 467
W +GEW C+ + + ++V+L T+ Y RV+NN G W + L
Sbjct: 293 WASGEWECTVSMAQGNASKKVEIVVLE----TSASYCPAERVANNRGDFRWPRTL 343
>AF378755-1|AAL11992.1| 1331|Homo sapiens tumor endothelial marker 5
precursor protein.
Length = 1331
Score = 30.7 bits (66), Expect = 7.1
Identities = 16/55 (29%), Positives = 26/55 (47%), Gaps = 1/55 (1%)
Frame = +3
Query: 306 WNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNN-GSVSWIKRL 467
W +GEW C+ + + ++V+L T+ Y RV+NN G W + L
Sbjct: 314 WASGEWECTVSMAQGNASKKVEIVVLE----TSASYCPAERVANNRGDFRWPRTL 364
>AB040964-1|BAA96055.2| 1206|Homo sapiens KIAA1531 protein protein.
Length = 1206
Score = 30.7 bits (66), Expect = 7.1
Identities = 16/55 (29%), Positives = 26/55 (47%), Gaps = 1/55 (1%)
Frame = +3
Query: 306 WNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNN-GSVSWIKRL 467
W +GEW C+ + + ++V+L T+ Y RV+NN G W + L
Sbjct: 406 WASGEWECTVSMAQGNASKKVEIVVLE----TSASYCPAERVANNRGDFRWPRTL 456
>AK122582-1|BAC56923.1| 1383|Homo sapiens FLJ00269 protein protein.
Length = 1383
Score = 30.3 bits (65), Expect = 9.4
Identities = 13/38 (34%), Positives = 18/38 (47%)
Frame = -2
Query: 429 HGRGERSPRRWLQPRLAVPRQASTSVPRTPAKCCSPTP 316
HG + SP W Q + + P + P P +CCS P
Sbjct: 256 HGGRDCSPTCWEQGKCSGPAEQEKRGPSFPKECCSQGP 293
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 126,809,207
Number of Sequences: 237096
Number of extensions: 2916048
Number of successful extensions: 7304
Number of sequences better than 10.0: 188
Number of HSP's better than 10.0 without gapping: 6582
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 7146
length of database: 76,859,062
effective HSP length: 89
effective length of database: 55,757,518
effective search space used: 10928473528
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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