Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BmNP06_FL5_I08
(843 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
AJ306454-1|CAC34819.1| 497|Homo sapiens neuronal nicotinic acet... 80 1e-14
Y08416-1|CAA69693.1| 498|Homo sapiens nicotinic acetylcholine r... 78 5e-14
U62439-1|AAB40117.1| 498|Homo sapiens nicotinic acetylcholine r... 78 5e-14
U48861-1|AAA92123.1| 498|Homo sapiens beta 4 nicotinic acetylch... 78 5e-14
BC096082-1|AAH96082.1| 498|Homo sapiens cholinergic receptor, n... 78 5e-14
BC096080-1|AAH96080.1| 498|Homo sapiens cholinergic receptor, n... 78 5e-14
AF306329-1|AAL02062.1| 498|Homo sapiens neuronal nicotinic acet... 78 5e-14
X68275-1|CAA48336.1| 451|Homo sapiens nicotinic receptor beta 4... 74 7e-13
Y08419-1|CAA69696.1| 468|Homo sapiens nicotinic acetylcholine r... 73 2e-12
U62434-1|AAB40112.1| 468|Homo sapiens nicotinic acetylcholine r... 73 2e-12
BC033639-1|AAH33639.1| 468|Homo sapiens cholinergic receptor, n... 73 2e-12
AJ306481-1|CAC34820.1| 468|Homo sapiens neuronal nicotinic acet... 73 2e-12
Y08417-1|CAA69694.1| 458|Homo sapiens nicotinic acetylcholine r... 72 3e-12
X67513-1|CAA47851.1| 423|Homo sapiens nicotinic acetylcholine ... 72 3e-12
U62438-1|AAB40116.1| 458|Homo sapiens nicotinic acetylcholine r... 72 3e-12
BC069788-1|AAH69788.1| 458|Homo sapiens cholinergic receptor, n... 72 3e-12
BC069703-1|AAH69703.1| 458|Homo sapiens cholinergic receptor, n... 72 3e-12
BC069681-1|AAH69681.1| 458|Homo sapiens cholinergic receptor, n... 72 3e-12
AF140765-1|AAD33063.1| 458|Homo sapiens neuronal acetylcholine ... 72 3e-12
M83712-1|AAA58357.1| 468|Homo sapiens nicotinic receptor alpha ... 71 4e-12
Y08418-1|CAA69695.1| 503|Homo sapiens nicotinic acetylcholine r... 71 7e-12
X53559-1|CAA37625.1| 474|Homo sapiens neuronal nicotinic acetyl... 71 7e-12
U62432-1|AAB40110.1| 504|Homo sapiens nicotinic acetylcholine r... 71 7e-12
M37981-1|AAA59942.1| 503|Homo sapiens neuronal nicotinic acetyl... 71 7e-12
BT006897-1|AAP35543.1| 505|Homo sapiens cholinergic receptor, n... 71 7e-12
BT006646-1|AAP35292.1| 489|Homo sapiens cholinergic receptor, n... 71 7e-12
BC098443-1|AAH98443.1| 504|Homo sapiens cholinergic receptor, n... 71 7e-12
BC006114-1|AAH06114.1| 489|Homo sapiens CHRNA3 protein protein. 71 7e-12
BC002996-1|AAH02996.1| 505|Homo sapiens cholinergic receptor, n... 71 7e-12
BC001642-1|AAH01642.1| 505|Homo sapiens cholinergic receptor, n... 71 7e-12
BC000513-1|AAH00513.1| 505|Homo sapiens cholinergic receptor, n... 71 7e-12
AJ007783-1|CAA07682.1| 504|Homo sapiens nicotinic acetylcholine... 71 7e-12
AF385584-1|AAK68110.1| 489|Homo sapiens nicotinic cholinergic r... 71 7e-12
Y16282-1|CAA76155.1| 494|Homo sapiens nicotinic acetylcholine r... 70 1e-11
U62435-1|AAB40113.1| 494|Homo sapiens nicotinic acetylcholine r... 70 1e-11
BC014456-1|AAH14456.1| 494|Homo sapiens cholinergic receptor, n... 70 1e-11
AJ001935-1|CAA05108.1| 504|Homo sapiens CHRNB2 protein. 70 1e-11
AB079251-1|BAC06855.1| 494|Homo sapiens Nicotinic acetylcholine... 70 1e-11
Y16281-1|CAA76154.1| 529|Homo sapiens nicotinic acetylcholine r... 69 2e-11
U62431-1|AAB40109.1| 529|Homo sapiens nicotinic acetylcholine r... 69 2e-11
Y08421-1|CAA69698.1| 627|Homo sapiens nicotinic acetylcholine r... 69 2e-11
Y08415-1|CAA69692.1| 502|Homo sapiens nicotinic acetylcholine r... 69 2e-11
X89741-1|CAA61893.1| 627|Homo sapiens neuronal acetylcholine re... 69 2e-11
X87629-1|CAA60959.1| 602|Homo sapiens nicotinic acetylcholine r... 69 2e-11
X53179-1|CAA37320.1| 502|Homo sapiens precursor peptide (AA -25... 69 2e-11
U62437-1|AAB40115.1| 502|Homo sapiens nicotinic acetylcholine r... 69 2e-11
U62433-1|AAB40111.1| 627|Homo sapiens nicotinic acetylcholine r... 69 2e-11
L35901-1|AAA64743.1| 627|Homo sapiens nicotinic acetylcholine r... 69 2e-11
DQ093071-1|AAY88737.1| 627|Homo sapiens cholinergic receptor, n... 69 2e-11
BC096290-1|AAH96290.1| 627|Homo sapiens cholinergic receptor, n... 69 2e-11
BC075041-1|AAH75041.1| 502|Homo sapiens cholinergic receptor, n... 69 2e-11
BC075040-1|AAH75040.1| 502|Homo sapiens cholinergic receptor, n... 69 2e-11
AL592078-3|CAI16184.1| 502|Homo sapiens cholinergic receptor, n... 69 2e-11
AF077186-1|AAD45422.1| 502|Homo sapiens neuronal nicotinic acet... 69 2e-11
M86383-1|AAC84176.1| 502|Homo sapiens nicotinic acetylcholine r... 68 4e-11
X14830-1|CAA32939.1| 501|Homo sapiens protein ( Human mRNA for ... 65 3e-10
BC011371-1|AAH11371.1| 501|Homo sapiens cholinergic receptor, n... 65 3e-10
DQ644022-1|ABG35128.1| 456|Homo sapiens 5-HT3 receptor subunit ... 64 6e-10
BC101183-1|AAI01184.1| 471|Homo sapiens 5-hydroxytryptamine (se... 64 6e-10
BC101182-1|AAI01183.1| 471|Homo sapiens 5-hydroxytryptamine (se... 64 6e-10
AY159813-1|AAO38167.2| 471|Homo sapiens 5-hydroxytryptamine ser... 64 6e-10
BC023553-1|AAH23553.1| 501|Homo sapiens cholinergic receptor, n... 64 8e-10
X66403-1|CAA47030.1| 493|Homo sapiens acetylcholine receptor ep... 63 1e-09
BC131799-1|AAI31800.1| 447|Homo sapiens 5-hydroxytryptamine (se... 63 1e-09
BC101185-1|AAI01186.1| 374|Homo sapiens HTR3E protein protein. 63 1e-09
AF105999-1|AAD24503.1| 493|Homo sapiens acetylcholine receptor ... 63 1e-09
AF459285-1|AAL66182.1| 447|Homo sapiens 5-hydroxytryptamine rec... 63 1e-09
AY349353-1|AAQ93477.1| 456|Homo sapiens 5-HT3c1 serotonin recep... 62 2e-09
AY349352-1|AAQ93476.1| 441|Homo sapiens 5-HT3c1 serotonin recep... 62 2e-09
BC113575-1|AAI13576.1| 479|Homo sapiens cholinergic receptor, n... 62 3e-09
BC113549-1|AAI13550.1| 479|Homo sapiens cholinergic receptor, n... 62 3e-09
AY123244-1|AAM74523.1| 479|Homo sapiens nicotinic acetylcholine... 62 3e-09
AJ243342-1|CAB65091.1| 479|Homo sapiens nicotinic acetylcholine... 62 3e-09
AC118275-1|AAY40986.1| 479|Homo sapiens unknown protein. 62 3e-09
X01715-1|CAA25861.1| 520|Homo sapiens acetylcholine receptor ga... 61 6e-09
AC092165-3|AAY24103.1| 520|Homo sapiens unknown protein. 61 6e-09
Y00762-1|CAA68731.1| 457|Homo sapiens protein ( Human mRNA for ... 60 7e-09
X02502-1|CAA26344.1| 457|Homo sapiens acetylcholine receptor pr... 60 7e-09
S77094-1|AAD14247.1| 457|Homo sapiens nicotinic acetylcholine r... 60 7e-09
BC006314-1|AAH06314.1| 269|Homo sapiens CHRNA1 protein protein. 60 7e-09
AF227732-1|AAF61920.1| 470|Homo sapiens nicotinic acetylcholine... 60 7e-09
AC018890-1|AAY14687.1| 457|Homo sapiens unknown protein. 60 7e-09
AJ295237-1|CAC16144.1| 450|Homo sapiens neuronal nicotinic acet... 58 3e-08
AJ278118-1|CAC20435.1| 450|Homo sapiens neuronal nicotinic acet... 58 3e-08
AF327367-1|AAK14333.1| 450|Homo sapiens nicotinic acetylcholine... 58 3e-08
AF199235-1|AAG00795.2| 450|Homo sapiens nicotinic acetylcholine... 58 3e-08
S77554-1|AAB33983.1| 474|Homo sapiens GABAA receptor beta 2 sub... 58 4e-08
S77553-1|AAB33982.1| 512|Homo sapiens GABAA receptor beta 2 sub... 58 4e-08
S67368-1|AAB29370.1| 474|Homo sapiens gamma-aminobutyric acid A... 58 4e-08
BC105639-1|AAI05640.1| 474|Homo sapiens GABRB2 protein protein. 58 4e-08
BC099719-1|AAH99719.1| 474|Homo sapiens GABRB2 protein protein. 58 4e-08
BC099705-1|AAH99705.1| 474|Homo sapiens GABRB2 protein protein. 58 4e-08
Z23141-1|CAA80672.1| 479|Homo sapiens cholinergic receptor, nic... 56 1e-07
Y08420-1|CAA69697.1| 502|Homo sapiens nicotinic acetylcholine r... 56 1e-07
X70297-1|CAA49778.1| 502|Homo sapiens neuronal nicotinic acetyl... 56 1e-07
X55019-1|CAA38759.1| 517|Homo sapiens acetylcholine receptor de... 56 1e-07
U62436-1|AAB40114.1| 502|Homo sapiens nicotinic acetylcholine r... 56 1e-07
BC093925-1|AAH93925.1| 517|Homo sapiens cholinergic receptor, n... 56 1e-07
BC093923-1|AAH93923.1| 517|Homo sapiens cholinergic receptor, n... 56 1e-07
AJ586911-1|CAE52911.1| 502|Homo sapiens nicotinic acetylcholine... 56 1e-07
AC092165-2|AAY24102.1| 517|Homo sapiens unknown protein. 56 1e-07
U40583-1|AAA83561.1| 502|Homo sapiens alpha 7 neuronal nicotini... 55 3e-07
AF385585-1|AAK68111.1| 502|Homo sapiens nicotinic cholinergic r... 55 3e-07
BC110597-1|AAI10598.1| 411|Homo sapiens ligand-gated ion channe... 54 5e-07
AF512521-1|AAO20969.1| 411|Homo sapiens ligand-gated ion channe... 54 5e-07
L08485-1|AAA58490.1| 462|Homo sapiens GABA-benzodiazepine recep... 54 6e-07
BT009830-1|AAP88832.1| 462|Homo sapiens gamma-aminobutyric acid... 54 6e-07
BC113422-1|AAI13423.1| 462|Homo sapiens gamma-aminobutyric acid... 54 6e-07
BC111979-1|AAI11980.1| 462|Homo sapiens gamma-aminobutyric acid... 54 6e-07
AB223030-1|BAE19924.1| 411|Homo sapiens ligand-gated ion-channe... 54 6e-07
M59216-1|AAA35862.1| 474|Homo sapiens gamma-aminobutyric acid r... 54 9e-07
X14767-1|CAA32875.1| 474|Homo sapiens GABA-A receptor beta 1 su... 53 1e-06
BC111802-1|AAI11803.1| 465|Homo sapiens CHRNG protein protein. 51 5e-06
BC028629-1|AAH28629.1| 492|Homo sapiens gamma-aminobutyric acid... 51 5e-06
S82769-1|AAB39369.1| 467|Homo sapiens GABAA receptor gamma 3 su... 51 6e-06
S62908-1|AAB27279.1| 492|Homo sapiens gamma-aminobutyric acidA ... 51 6e-06
AK122638-1|BAC85499.1| 266|Homo sapiens yte protein of 76kDa) (... 51 6e-06
AF269144-1|AAF99698.1| 467|Homo sapiens GABAA receptor gamma 3 ... 51 6e-06
AF228458-1|AAF63215.1| 449|Homo sapiens GABAA receptor gamma 3 ... 51 6e-06
AF166361-1|AAG12455.1| 492|Homo sapiens GABA receptor subunit a... 51 6e-06
U77731-2|AAB38273.1| 360|Homo sapiens glycine receptor alpha 2B... 50 1e-05
CR450343-1|CAG29339.1| 452|Homo sapiens GLRA2 protein. 50 1e-05
AY437084-1|AAR87843.1| 452|Homo sapiens glycine receptor alpha2... 50 1e-05
AJ003080-1|CAA05853.1| 238|Homo sapiens serotonin receptor prot... 50 1e-05
X52008-1|CAA36257.1| 452|Homo sapiens inhibitory glycine recept... 50 1e-05
U77731-1|AAB38272.1| 360|Homo sapiens glycine receptor alpha 2 ... 50 1e-05
S82612-1|AAB37533.2| 478|Homo sapiens 5-hydroxytryptamine type ... 50 1e-05
BC032864-1|AAH32864.1| 452|Homo sapiens glycine receptor, alpha... 50 1e-05
AY437083-1|AAR87842.1| 452|Homo sapiens glycine receptor alpha2... 50 1e-05
AF053495-1|AAC35290.1| 452|Homo sapiens glycine receptor alpha ... 50 1e-05
S81944-1|AAB36480.1| 453|Homo sapiens gamma-aminobutyric acid t... 49 2e-05
D49394-1|BAA08387.1| 478|Homo sapiens serotonin 5-HT3 receptor ... 49 2e-05
BT007204-1|AAP35868.1| 484|Homo sapiens 5-hydroxytryptamine (se... 49 2e-05
BC099641-1|AAH99641.1| 453|Homo sapiens gamma-aminobutyric acid... 49 2e-05
BC099640-1|AAH99640.1| 453|Homo sapiens gamma-aminobutyric acid... 49 2e-05
BC096242-1|AAH96242.1| 453|Homo sapiens gamma-aminobutyric acid... 49 2e-05
BC096241-1|AAH96241.1| 453|Homo sapiens gamma-aminobutyric acid... 49 2e-05
BC004453-1|AAH04453.2| 478|Homo sapiens 5-hydroxytryptamine (se... 49 2e-05
BC002354-1|AAH02354.1| 478|Homo sapiens 5-hydroxytryptamine (se... 49 2e-05
AJ005205-1|CAA06442.3| 478|Homo sapiens serotonin 3 receptor pr... 49 2e-05
AJ003079-1|CAA05852.1| 478|Homo sapiens 5-hydroxytryptamine3 re... 49 2e-05
AJ003078-1|CAA05851.1| 510|Homo sapiens serotonin receptor prot... 49 2e-05
AF498984-1|AAM21131.1| 478|Homo sapiens 5-hydroxytryptamine rec... 49 2e-05
U30461-1|AAB52519.1| 554|Homo sapiens GABAA receptor subunit al... 48 3e-05
BC035055-1|AAH35055.1| 554|Homo sapiens gamma-aminobutyric acid... 48 3e-05
BC022449-1|AAH22449.1| 474|Homo sapiens gamma-aminobutyric acid... 48 3e-05
U95367-1|AAC51357.1| 440|Homo sapiens GABA-A receptor pi subuni... 47 1e-04
BC109211-1|AAI09212.1| 632|Homo sapiens gamma-aminobutyric acid... 47 1e-04
BC109210-1|AAI09211.1| 632|Homo sapiens gamma-aminobutyric acid... 47 1e-04
BC109106-1|AAI09107.1| 440|Homo sapiens gamma-aminobutyric acid... 47 1e-04
BC109105-1|AAI09106.1| 440|Homo sapiens gamma-aminobutyric acid... 47 1e-04
BC074865-1|AAH74865.1| 440|Homo sapiens gamma-aminobutyric acid... 47 1e-04
BC074810-1|AAH74810.1| 440|Homo sapiens gamma-aminobutyric acid... 47 1e-04
BC033801-1|AAH33801.1| 452|Homo sapiens gamma-aminobutyric acid... 47 1e-04
AL391845-4|CAI15436.1| 452|Homo sapiens gamma-aminobutyric acid... 47 1e-04
AF189259-1|AAF70380.1| 632|Homo sapiens GABA-A receptor theta s... 47 1e-04
AF144648-1|AAD51172.1| 627|Homo sapiens GABA-A receptor theta p... 47 1e-04
AF016917-1|AAB70007.1| 452|Homo sapiens GABA-A receptor delta s... 47 1e-04
AF009702-1|AAC24194.1| 440|Homo sapiens GABA-A receptor pi subu... 47 1e-04
BC096083-1|AAH96083.1| 198|Homo sapiens CHRNB4 protein protein. 46 1e-04
BC096081-1|AAH96081.1| 198|Homo sapiens CHRNB4 protein protein. 46 1e-04
BC074795-1|AAH74795.1| 467|Homo sapiens gamma-aminobutyric acid... 46 2e-04
BC069348-1|AAH69348.1| 467|Homo sapiens gamma-aminobutyric acid... 46 2e-04
BC059389-1|AAH59389.1| 475|Homo sapiens gamma-aminobutyric acid... 46 2e-04
AF165124-1|AAD50273.1| 467|Homo sapiens gamma-aminobutyric acid... 46 2e-04
X52009-1|CAA36258.1| 449|Homo sapiens inhibitory glycine recept... 46 2e-04
X15376-1|CAA33437.1| 467|Homo sapiens GABA-A receptor gamma 2 s... 45 3e-04
BC031087-1|AAH31087.1| 465|Homo sapiens gamma-aminobutyric acid... 45 3e-04
BC114947-1|AAI14948.1| 457|Homo sapiens GLRA1 protein protein. 45 4e-04
BC074980-1|AAH74980.1| 449|Homo sapiens glycine receptor, alpha... 45 4e-04
AB209359-1|BAD92596.1| 533|Homo sapiens cholinergic receptor, n... 44 7e-04
Z93848-1|CAI41994.1| 376|Homo sapiens glycine receptor, alpha 4... 44 0.001
U93917-1|AAC39917.1| 449|Homo sapiens glycine receptor alpha 3 ... 44 0.001
BC036086-1|AAH36086.1| 464|Homo sapiens glycine receptor, alpha... 44 0.001
AL049610-1|CAI42158.1| 376|Homo sapiens glycine receptor, alpha... 44 0.001
AF017724-1|AAC39919.1| 465|Homo sapiens glycine receptor alpha ... 44 0.001
BC096291-1|AAH96291.1| 556|Homo sapiens CHRNA4 protein protein. 43 0.001
BC114967-1|AAI14968.1| 366|Homo sapiens GLRA1 protein protein. 42 0.002
BC146774-1|AAI46775.1| 1114|Homo sapiens GPR124 protein protein. 31 6.9
AY181242-1|AAO27354.1| 1331|Homo sapiens G protein-coupled recep... 31 6.9
AK074099-1|BAB84925.1| 1310|Homo sapiens FLJ00170 protein protein. 31 6.9
AF378755-1|AAL11992.1| 1331|Homo sapiens tumor endothelial marke... 31 6.9
AB040964-1|BAA96055.2| 1206|Homo sapiens KIAA1531 protein protein. 31 6.9
>AJ306454-1|CAC34819.1| 497|Homo sapiens neuronal nicotinic
acetylcholine receptor beta-4 subunit protein.
Length = 497
Score = 79.8 bits (188), Expect = 1e-14
Identities = 54/192 (28%), Positives = 89/192 (46%), Gaps = 11/192 (5%)
Frame = +3
Query: 66 AIASAAECENATSLSLMIDSLL--ATYDRESPP--DSKIVVNLTLHLRHA---NIRESES 224
A+ C A + ++D LL Y+ P S ++++ L L A ++ E E
Sbjct: 14 ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQ 73
Query: 225 TVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRAR 401
+ L+ W D RL+WN+ + G + + ++R+W PD+VL N T
Sbjct: 74 IMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNDGTYEVSVYTNLI 133
Query: 402 VSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDKRIYSMFE 581
V +NGSV W+ + +++ +P D Q CT KF S ++ E+D V+ SM +
Sbjct: 134 VRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRSWTYDHTEIDMVLMTPTASMDD 193
Query: 582 ---SGAWDVTDL 608
SG WD+ L
Sbjct: 194 FTPSGEWDIVAL 205
>Y08416-1|CAA69693.1| 498|Homo sapiens nicotinic acetylcholine
receptor beta4 subunit precursor protein.
Length = 498
Score = 77.8 bits (183), Expect = 5e-14
Identities = 55/193 (28%), Positives = 90/193 (46%), Gaps = 12/193 (6%)
Frame = +3
Query: 66 AIASAAECENATSLSLMIDSLL--ATYDRESPP--DSKIVVNLTLHLRHA---NIRESES 224
A+ C A + ++D LL Y+ P S ++++ L L A ++ E E
Sbjct: 14 ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQ 73
Query: 225 TVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRA 398
+ L+ W D RL+WN+ + G + + ++R+W PD+VL N A T
Sbjct: 74 IMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNADGTYEVSVYTNL 133
Query: 399 RVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDKRIYSMF 578
V +NGSV W+ + +++ +P D Q CT KF S ++ E+D V+ SM
Sbjct: 134 IVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRSWTYDHTEIDMVLMTPTASMD 193
Query: 579 E---SGAWDVTDL 608
+ SG WD+ L
Sbjct: 194 DFTPSGEWDIVAL 206
>U62439-1|AAB40117.1| 498|Homo sapiens nicotinic acetylcholine
receptor beta4 subunit precursor protein.
Length = 498
Score = 77.8 bits (183), Expect = 5e-14
Identities = 55/193 (28%), Positives = 90/193 (46%), Gaps = 12/193 (6%)
Frame = +3
Query: 66 AIASAAECENATSLSLMIDSLL--ATYDRESPP--DSKIVVNLTLHLRHA---NIRESES 224
A+ C A + ++D LL Y+ P S ++++ L L A ++ E E
Sbjct: 14 ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQ 73
Query: 225 TVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRA 398
+ L+ W D RL+WN+ + G + + ++R+W PD+VL N A T
Sbjct: 74 IMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNADGTYEVSVYTNL 133
Query: 399 RVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDKRIYSMF 578
V +NGSV W+ + +++ +P D Q CT KF S ++ E+D V+ SM
Sbjct: 134 IVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRSWTYDHTEIDMVLMTPTASMD 193
Query: 579 E---SGAWDVTDL 608
+ SG WD+ L
Sbjct: 194 DFTPSGEWDIVAL 206
>U48861-1|AAA92123.1| 498|Homo sapiens beta 4 nicotinic
acetylcholine receptor subunit protein.
Length = 498
Score = 77.8 bits (183), Expect = 5e-14
Identities = 55/193 (28%), Positives = 90/193 (46%), Gaps = 12/193 (6%)
Frame = +3
Query: 66 AIASAAECENATSLSLMIDSLL--ATYDRESPP--DSKIVVNLTLHLRHA---NIRESES 224
A+ C A + ++D LL Y+ P S ++++ L L A ++ E E
Sbjct: 14 ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQ 73
Query: 225 TVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRA 398
+ L+ W D RL+WN+ + G + + ++R+W PD+VL N A T
Sbjct: 74 IMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNADGTYEVSVYTNL 133
Query: 399 RVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDKRIYSMF 578
V +NGSV W+ + +++ +P D Q CT KF S ++ E+D V+ SM
Sbjct: 134 IVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRSWTYDHTEIDMVLMTPTASMD 193
Query: 579 E---SGAWDVTDL 608
+ SG WD+ L
Sbjct: 194 DFTPSGEWDIVAL 206
>BC096082-1|AAH96082.1| 498|Homo sapiens cholinergic receptor,
nicotinic, beta 4 protein.
Length = 498
Score = 77.8 bits (183), Expect = 5e-14
Identities = 55/193 (28%), Positives = 90/193 (46%), Gaps = 12/193 (6%)
Frame = +3
Query: 66 AIASAAECENATSLSLMIDSLL--ATYDRESPP--DSKIVVNLTLHLRHA---NIRESES 224
A+ C A + ++D LL Y+ P S ++++ L L A ++ E E
Sbjct: 14 ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQ 73
Query: 225 TVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRA 398
+ L+ W D RL+WN+ + G + + ++R+W PD+VL N A T
Sbjct: 74 IMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNADGTYEVSVYTNL 133
Query: 399 RVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDKRIYSMF 578
V +NGSV W+ + +++ +P D Q CT KF S ++ E+D V+ SM
Sbjct: 134 IVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRSWTYDHTEIDMVLMTPTASMD 193
Query: 579 E---SGAWDVTDL 608
+ SG WD+ L
Sbjct: 194 DFTPSGEWDIVAL 206
>BC096080-1|AAH96080.1| 498|Homo sapiens cholinergic receptor,
nicotinic, beta 4 protein.
Length = 498
Score = 77.8 bits (183), Expect = 5e-14
Identities = 55/193 (28%), Positives = 90/193 (46%), Gaps = 12/193 (6%)
Frame = +3
Query: 66 AIASAAECENATSLSLMIDSLL--ATYDRESPP--DSKIVVNLTLHLRHA---NIRESES 224
A+ C A + ++D LL Y+ P S ++++ L L A ++ E E
Sbjct: 14 ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQ 73
Query: 225 TVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRA 398
+ L+ W D RL+WN+ + G + + ++R+W PD+VL N A T
Sbjct: 74 IMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNADGTYEVSVYTNL 133
Query: 399 RVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDKRIYSMF 578
V +NGSV W+ + +++ +P D Q CT KF S ++ E+D V+ SM
Sbjct: 134 IVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRSWTYDHTEIDMVLMTPTASMD 193
Query: 579 E---SGAWDVTDL 608
+ SG WD+ L
Sbjct: 194 DFTPSGEWDIVAL 206
>AF306329-1|AAL02062.1| 498|Homo sapiens neuronal nicotinic
acetylcholine receptor beta 4 subunit protein.
Length = 498
Score = 77.8 bits (183), Expect = 5e-14
Identities = 55/193 (28%), Positives = 90/193 (46%), Gaps = 12/193 (6%)
Frame = +3
Query: 66 AIASAAECENATSLSLMIDSLL--ATYDRESPP--DSKIVVNLTLHLRHA---NIRESES 224
A+ C A + ++D LL Y+ P S ++++ L L A ++ E E
Sbjct: 14 ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQ 73
Query: 225 TVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRA 398
+ L+ W D RL+WN+ + G + + ++R+W PD+VL N A T
Sbjct: 74 IMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNADGTYEVSVYTNL 133
Query: 399 RVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDKRIYSMF 578
V +NGSV W+ + +++ +P D Q CT KF S ++ E+D V+ SM
Sbjct: 134 IVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRSWTYDHTEIDMVLMTPTASMD 193
Query: 579 E---SGAWDVTDL 608
+ SG WD+ L
Sbjct: 194 DFTPSGEWDIVAL 206
>X68275-1|CAA48336.1| 451|Homo sapiens nicotinic receptor beta 4
subunit protein.
Length = 451
Score = 73.7 bits (173), Expect = 7e-13
Identities = 46/153 (30%), Positives = 74/153 (48%), Gaps = 6/153 (3%)
Frame = +3
Query: 168 IVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 341
I + L L L ++ E + + L+ W D RL+WN+ + G + + ++R+W P
Sbjct: 7 ISIKLQLSLAQLISVNERDEIMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLP 66
Query: 342 DVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 518
D+VL N A T V +NGSV W+ + +++ +P D Q CT KF S
Sbjct: 67 DIVLYNNADGTYEVSVYTNLIVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRS 126
Query: 519 RMHNSDEMDFVIDKRIYSMFE---SGAWDVTDL 608
++ E+D V+ SM + SG WD+ L
Sbjct: 127 WTYDHTEIDMVLMTPTASMDDFTPSGEWDIVAL 159
>Y08419-1|CAA69696.1| 468|Homo sapiens nicotinic acetylcholine
receptor alpha5 subunit precursor protein.
Length = 468
Score = 72.5 bits (170), Expect = 2e-12
Identities = 43/173 (24%), Positives = 83/173 (47%), Gaps = 11/173 (6%)
Frame = +3
Query: 114 MIDSLLATYDRESPP----DSKIVVNLTLHLRH-ANIRESESTVRILADLQMNWIDKRLS 278
++ L Y+R P + KI + L + ++ E + L+ WID +L
Sbjct: 50 LLKDLFQDYERWVRPVEHLNDKIKIKFGLAISQLVDVDEKNQLMTTNVWLKQEWIDVKLR 109
Query: 279 WNAGEWG-CSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVSWIKRLDISTP 455
WN ++G V S+ +W PD+VL + A + + + NG+V+W + +
Sbjct: 110 WNPDDYGGIKVIRVPSDSVWTPDIVLFDNADGRFEGTSTKTVIRYNGTVTWTPPANYKSS 169
Query: 456 ISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFV-----IDKRIYSMFESGAWDV 599
++ + +P D+Q C+ KFGS ++ ++D + +DKR F++G W++
Sbjct: 170 CTIDVTFFPFDLQNCSMKFGSWTYDGSQVDIILEDQDVDKR--DFFDNGEWEI 220
>U62434-1|AAB40112.1| 468|Homo sapiens nicotinic acetylcholine
receptor alpha5 subunit precursor protein.
Length = 468
Score = 72.5 bits (170), Expect = 2e-12
Identities = 43/173 (24%), Positives = 83/173 (47%), Gaps = 11/173 (6%)
Frame = +3
Query: 114 MIDSLLATYDRESPP----DSKIVVNLTLHLRH-ANIRESESTVRILADLQMNWIDKRLS 278
++ L Y+R P + KI + L + ++ E + L+ WID +L
Sbjct: 50 LLKDLFQDYERWVRPVEHLNDKIKIKFGLAISQLVDVDEKNQLMTTNVWLKQEWIDVKLR 109
Query: 279 WNAGEWG-CSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVSWIKRLDISTP 455
WN ++G V S+ +W PD+VL + A + + + NG+V+W + +
Sbjct: 110 WNPDDYGGIKVIRVPSDSVWTPDIVLFDNADGRFEGTSTKTVIRYNGTVTWTPPANYKSS 169
Query: 456 ISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFV-----IDKRIYSMFESGAWDV 599
++ + +P D+Q C+ KFGS ++ ++D + +DKR F++G W++
Sbjct: 170 CTIDVTFFPFDLQNCSMKFGSWTYDGSQVDIILEDQDVDKR--DFFDNGEWEI 220
>BC033639-1|AAH33639.1| 468|Homo sapiens cholinergic receptor,
nicotinic, alpha 5 protein.
Length = 468
Score = 72.5 bits (170), Expect = 2e-12
Identities = 43/173 (24%), Positives = 83/173 (47%), Gaps = 11/173 (6%)
Frame = +3
Query: 114 MIDSLLATYDRESPP----DSKIVVNLTLHLRH-ANIRESESTVRILADLQMNWIDKRLS 278
++ L Y+R P + KI + L + ++ E + L+ WID +L
Sbjct: 50 LLKDLFQDYERWVRPVEHLNDKIKIKFGLAISQLVDVDEKNQLMTTNVWLKQEWIDVKLR 109
Query: 279 WNAGEWG-CSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVSWIKRLDISTP 455
WN ++G V S+ +W PD+VL + A + + + NG+V+W + +
Sbjct: 110 WNPDDYGGIKVIRVPSDSVWTPDIVLFDNADGRFEGTSTKTVIRYNGTVTWTPPANYKSS 169
Query: 456 ISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFV-----IDKRIYSMFESGAWDV 599
++ + +P D+Q C+ KFGS ++ ++D + +DKR F++G W++
Sbjct: 170 CTIDVTFFPFDLQNCSMKFGSWTYDGSQVDIILEDQDVDKR--DFFDNGEWEI 220
>AJ306481-1|CAC34820.1| 468|Homo sapiens neuronal nicotinic
acetylcholine receptor alpha-5subunit protein.
Length = 468
Score = 72.5 bits (170), Expect = 2e-12
Identities = 43/173 (24%), Positives = 83/173 (47%), Gaps = 11/173 (6%)
Frame = +3
Query: 114 MIDSLLATYDRESPP----DSKIVVNLTLHLRH-ANIRESESTVRILADLQMNWIDKRLS 278
++ L Y+R P + KI + L + ++ E + L+ WID +L
Sbjct: 50 LLKDLFQDYERWVRPVEHLNDKIKIKFGLAISQLVDVDEKNQLMTTNVWLKQEWIDVKLR 109
Query: 279 WNAGEWG-CSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVSWIKRLDISTP 455
WN ++G V S+ +W PD+VL + A + + + NG+V+W + +
Sbjct: 110 WNPDDYGGIKVIRVPSDSVWTPDIVLFDNADGRFEGTSTKTVIRYNGTVTWTPPANYKSS 169
Query: 456 ISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFV-----IDKRIYSMFESGAWDV 599
++ + +P D+Q C+ KFGS ++ ++D + +DKR F++G W++
Sbjct: 170 CTIDVTFFPFDLQNCSMKFGSWTYDGSQVDIILEDQDVDKR--DFFDNGEWEI 220
>Y08417-1|CAA69694.1| 458|Homo sapiens nicotinic acetylcholine
receptor beta3 subunit precursor protein.
Length = 458
Score = 71.7 bits (168), Expect = 3e-12
Identities = 38/123 (30%), Positives = 63/123 (51%), Gaps = 5/123 (4%)
Frame = +3
Query: 246 LQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLL-NAAATTAGDYALRARVSNNGS 419
L+ W D +L WN ++G + V SE LW PD+VL NA G + V +NG+
Sbjct: 81 LKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFEGSLMTKVIVKSNGT 140
Query: 420 VSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFV-IDKRI--YSMFESGA 590
V W + +M + +P D Q C+ KFGS ++ +D + I++ + F++G
Sbjct: 141 VVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGTMVDLILINENVDRKDFFDNGE 200
Query: 591 WDV 599
W++
Sbjct: 201 WEI 203
>X67513-1|CAA47851.1| 423|Homo sapiens nicotinic acetylcholine
receptor beta-3 subunit protein.
Length = 423
Score = 71.7 bits (168), Expect = 3e-12
Identities = 38/123 (30%), Positives = 63/123 (51%), Gaps = 5/123 (4%)
Frame = +3
Query: 246 LQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLL-NAAATTAGDYALRARVSNNGS 419
L+ W D +L WN ++G + V SE LW PD+VL NA G + V +NG+
Sbjct: 46 LKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFEGSLMTKVIVKSNGT 105
Query: 420 VSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFV-IDKRI--YSMFESGA 590
V W + +M + +P D Q C+ KFGS ++ +D + I++ + F++G
Sbjct: 106 VVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGTMVDLILINENVDRKDFFDNGE 165
Query: 591 WDV 599
W++
Sbjct: 166 WEI 168
>U62438-1|AAB40116.1| 458|Homo sapiens nicotinic acetylcholine
receptor beta3 subunit precursor protein.
Length = 458
Score = 71.7 bits (168), Expect = 3e-12
Identities = 38/123 (30%), Positives = 63/123 (51%), Gaps = 5/123 (4%)
Frame = +3
Query: 246 LQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLL-NAAATTAGDYALRARVSNNGS 419
L+ W D +L WN ++G + V SE LW PD+VL NA G + V +NG+
Sbjct: 81 LKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFEGSLMTKVIVKSNGT 140
Query: 420 VSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFV-IDKRI--YSMFESGA 590
V W + +M + +P D Q C+ KFGS ++ +D + I++ + F++G
Sbjct: 141 VVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGTMVDLILINENVDRKDFFDNGE 200
Query: 591 WDV 599
W++
Sbjct: 201 WEI 203
>BC069788-1|AAH69788.1| 458|Homo sapiens cholinergic receptor,
nicotinic, beta 3 protein.
Length = 458
Score = 71.7 bits (168), Expect = 3e-12
Identities = 38/123 (30%), Positives = 63/123 (51%), Gaps = 5/123 (4%)
Frame = +3
Query: 246 LQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLL-NAAATTAGDYALRARVSNNGS 419
L+ W D +L WN ++G + V SE LW PD+VL NA G + V +NG+
Sbjct: 81 LKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFEGSLMTKVIVKSNGT 140
Query: 420 VSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFV-IDKRI--YSMFESGA 590
V W + +M + +P D Q C+ KFGS ++ +D + I++ + F++G
Sbjct: 141 VVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGTMVDLILINENVDRKDFFDNGE 200
Query: 591 WDV 599
W++
Sbjct: 201 WEI 203
>BC069703-1|AAH69703.1| 458|Homo sapiens cholinergic receptor,
nicotinic, beta 3 protein.
Length = 458
Score = 71.7 bits (168), Expect = 3e-12
Identities = 38/123 (30%), Positives = 63/123 (51%), Gaps = 5/123 (4%)
Frame = +3
Query: 246 LQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLL-NAAATTAGDYALRARVSNNGS 419
L+ W D +L WN ++G + V SE LW PD+VL NA G + V +NG+
Sbjct: 81 LKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFEGSLMTKVIVKSNGT 140
Query: 420 VSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFV-IDKRI--YSMFESGA 590
V W + +M + +P D Q C+ KFGS ++ +D + I++ + F++G
Sbjct: 141 VVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGTMVDLILINENVDRKDFFDNGE 200
Query: 591 WDV 599
W++
Sbjct: 201 WEI 203
>BC069681-1|AAH69681.1| 458|Homo sapiens cholinergic receptor,
nicotinic, beta 3 protein.
Length = 458
Score = 71.7 bits (168), Expect = 3e-12
Identities = 38/123 (30%), Positives = 63/123 (51%), Gaps = 5/123 (4%)
Frame = +3
Query: 246 LQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLL-NAAATTAGDYALRARVSNNGS 419
L+ W D +L WN ++G + V SE LW PD+VL NA G + V +NG+
Sbjct: 81 LKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFEGSLMTKVIVKSNGT 140
Query: 420 VSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFV-IDKRI--YSMFESGA 590
V W + +M + +P D Q C+ KFGS ++ +D + I++ + F++G
Sbjct: 141 VVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGTMVDLILINENVDRKDFFDNGE 200
Query: 591 WDV 599
W++
Sbjct: 201 WEI 203
>AF140765-1|AAD33063.1| 458|Homo sapiens neuronal acetylcholine
receptor beta-3 subunit precursor protein.
Length = 458
Score = 71.7 bits (168), Expect = 3e-12
Identities = 38/123 (30%), Positives = 63/123 (51%), Gaps = 5/123 (4%)
Frame = +3
Query: 246 LQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLL-NAAATTAGDYALRARVSNNGS 419
L+ W D +L WN ++G + V SE LW PD+VL NA G + V +NG+
Sbjct: 81 LKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFEGSLMTKVIVKSNGT 140
Query: 420 VSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFV-IDKRI--YSMFESGA 590
V W + +M + +P D Q C+ KFGS ++ +D + I++ + F++G
Sbjct: 141 VVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGTMVDLILINENVDRKDFFDNGE 200
Query: 591 WDV 599
W++
Sbjct: 201 WEI 203
>M83712-1|AAA58357.1| 468|Homo sapiens nicotinic receptor alpha 5
subunit protein.
Length = 468
Score = 71.3 bits (167), Expect = 4e-12
Identities = 43/173 (24%), Positives = 82/173 (47%), Gaps = 11/173 (6%)
Frame = +3
Query: 114 MIDSLLATYDRESPP----DSKIVVNLTLHLRH-ANIRESESTVRILADLQMNWIDKRLS 278
++ L Y+R P + KI + L + ++ E + L+ WID +L
Sbjct: 50 LLKDLFQDYERWVRPVEHLNDKIKIKFGLAISQLVDVDEKNQLMTTNVWLKQEWIDVKLR 109
Query: 279 WNAGEWG-CSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVSWIKRLDISTP 455
WN ++G V S+ W PD+VL + A + + + NG+V+W + +
Sbjct: 110 WNPDDYGGIKVIRVPSDSSWTPDIVLFDNADGRFEGTSTKTVIRYNGTVTWTPPANYKSS 169
Query: 456 ISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFV-----IDKRIYSMFESGAWDV 599
++ + +P D+Q C+ KFGS ++ ++D + +DKR F++G W++
Sbjct: 170 CTIDVTFFPFDLQNCSMKFGSWTYDGSQVDIILEDQDVDKR--DFFDNGEWEI 220
>Y08418-1|CAA69695.1| 503|Homo sapiens nicotinic acetylcholine
receptor alpha3 subunit precursor protein.
Length = 503
Score = 70.5 bits (165), Expect = 7e-12
Identities = 36/123 (29%), Positives = 64/123 (52%), Gaps = 5/123 (4%)
Frame = +3
Query: 246 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 419
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 85 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 144
Query: 420 VSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVI---DKRIYSMFESGA 590
V+WI + + + +P D Q CT KFGS ++ ++D V+ + +ESG
Sbjct: 145 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVLIGSSMNLKDYWESGE 204
Query: 591 WDV 599
W +
Sbjct: 205 WAI 207
>X53559-1|CAA37625.1| 474|Homo sapiens neuronal nicotinic
acetylcholine receptor alpha-3merase protein.
Length = 474
Score = 70.5 bits (165), Expect = 7e-12
Identities = 36/123 (29%), Positives = 64/123 (52%), Gaps = 5/123 (4%)
Frame = +3
Query: 246 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 419
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 56 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 115
Query: 420 VSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVI---DKRIYSMFESGA 590
V+WI + + + +P D Q CT KFGS ++ ++D V+ + +ESG
Sbjct: 116 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVLIGSSMNLKDYWESGE 175
Query: 591 WDV 599
W +
Sbjct: 176 WAI 178
>U62432-1|AAB40110.1| 504|Homo sapiens nicotinic acetylcholine
receptor alpha3 subunit precursor protein.
Length = 504
Score = 70.5 bits (165), Expect = 7e-12
Identities = 36/123 (29%), Positives = 64/123 (52%), Gaps = 5/123 (4%)
Frame = +3
Query: 246 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 419
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 86 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 145
Query: 420 VSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVI---DKRIYSMFESGA 590
V+WI + + + +P D Q CT KFGS ++ ++D V+ + +ESG
Sbjct: 146 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVLIGSSMNLKDYWESGE 205
Query: 591 WDV 599
W +
Sbjct: 206 WAI 208
>M37981-1|AAA59942.1| 503|Homo sapiens neuronal nicotinic
acetylcholine receptor protein.
Length = 503
Score = 70.5 bits (165), Expect = 7e-12
Identities = 36/123 (29%), Positives = 64/123 (52%), Gaps = 5/123 (4%)
Frame = +3
Query: 246 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 419
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 85 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 144
Query: 420 VSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVI---DKRIYSMFESGA 590
V+WI + + + +P D Q CT KFGS ++ ++D V+ + +ESG
Sbjct: 145 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVLIGSSMNLKDYWESGE 204
Query: 591 WDV 599
W +
Sbjct: 205 WAI 207
>BT006897-1|AAP35543.1| 505|Homo sapiens cholinergic receptor,
nicotinic, alpha polypeptide 3 protein.
Length = 505
Score = 70.5 bits (165), Expect = 7e-12
Identities = 36/123 (29%), Positives = 64/123 (52%), Gaps = 5/123 (4%)
Frame = +3
Query: 246 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 419
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 87 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 146
Query: 420 VSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVI---DKRIYSMFESGA 590
V+WI + + + +P D Q CT KFGS ++ ++D V+ + +ESG
Sbjct: 147 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVLIGSSMNLKDYWESGE 206
Query: 591 WDV 599
W +
Sbjct: 207 WAI 209
>BT006646-1|AAP35292.1| 489|Homo sapiens cholinergic receptor,
nicotinic, alpha polypeptide 3 protein.
Length = 489
Score = 70.5 bits (165), Expect = 7e-12
Identities = 36/123 (29%), Positives = 64/123 (52%), Gaps = 5/123 (4%)
Frame = +3
Query: 246 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 419
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 87 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 146
Query: 420 VSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVI---DKRIYSMFESGA 590
V+WI + + + +P D Q CT KFGS ++ ++D V+ + +ESG
Sbjct: 147 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVLIGSSMNLKDYWESGE 206
Query: 591 WDV 599
W +
Sbjct: 207 WAI 209
>BC098443-1|AAH98443.1| 504|Homo sapiens cholinergic receptor,
nicotinic, alpha 3 protein.
Length = 504
Score = 70.5 bits (165), Expect = 7e-12
Identities = 36/123 (29%), Positives = 64/123 (52%), Gaps = 5/123 (4%)
Frame = +3
Query: 246 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 419
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 86 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 145
Query: 420 VSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVI---DKRIYSMFESGA 590
V+WI + + + +P D Q CT KFGS ++ ++D V+ + +ESG
Sbjct: 146 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVLIGSSMNLKDYWESGE 205
Query: 591 WDV 599
W +
Sbjct: 206 WAI 208
>BC006114-1|AAH06114.1| 489|Homo sapiens CHRNA3 protein protein.
Length = 489
Score = 70.5 bits (165), Expect = 7e-12
Identities = 36/123 (29%), Positives = 64/123 (52%), Gaps = 5/123 (4%)
Frame = +3
Query: 246 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 419
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 87 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 146
Query: 420 VSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVI---DKRIYSMFESGA 590
V+WI + + + +P D Q CT KFGS ++ ++D V+ + +ESG
Sbjct: 147 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVLIGSSMNLKDYWESGE 206
Query: 591 WDV 599
W +
Sbjct: 207 WAI 209
>BC002996-1|AAH02996.1| 505|Homo sapiens cholinergic receptor,
nicotinic, alpha 3 protein.
Length = 505
Score = 70.5 bits (165), Expect = 7e-12
Identities = 36/123 (29%), Positives = 64/123 (52%), Gaps = 5/123 (4%)
Frame = +3
Query: 246 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 419
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 87 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 146
Query: 420 VSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVI---DKRIYSMFESGA 590
V+WI + + + +P D Q CT KFGS ++ ++D V+ + +ESG
Sbjct: 147 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVLIGSSMNLKDYWESGE 206
Query: 591 WDV 599
W +
Sbjct: 207 WAI 209
>BC001642-1|AAH01642.1| 505|Homo sapiens cholinergic receptor,
nicotinic, alpha 3 protein.
Length = 505
Score = 70.5 bits (165), Expect = 7e-12
Identities = 36/123 (29%), Positives = 64/123 (52%), Gaps = 5/123 (4%)
Frame = +3
Query: 246 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 419
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 87 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 146
Query: 420 VSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVI---DKRIYSMFESGA 590
V+WI + + + +P D Q CT KFGS ++ ++D V+ + +ESG
Sbjct: 147 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVLIGSSMNLKDYWESGE 206
Query: 591 WDV 599
W +
Sbjct: 207 WAI 209
>BC000513-1|AAH00513.1| 505|Homo sapiens cholinergic receptor,
nicotinic, alpha 3 protein.
Length = 505
Score = 70.5 bits (165), Expect = 7e-12
Identities = 36/123 (29%), Positives = 64/123 (52%), Gaps = 5/123 (4%)
Frame = +3
Query: 246 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 419
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 87 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 146
Query: 420 VSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVI---DKRIYSMFESGA 590
V+WI + + + +P D Q CT KFGS ++ ++D V+ + +ESG
Sbjct: 147 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVLIGSSMNLKDYWESGE 206
Query: 591 WDV 599
W +
Sbjct: 207 WAI 209
>AJ007783-1|CAA07682.1| 504|Homo sapiens nicotinic acetylcholine
receptor alpha-3 subunit protein.
Length = 504
Score = 70.5 bits (165), Expect = 7e-12
Identities = 36/123 (29%), Positives = 64/123 (52%), Gaps = 5/123 (4%)
Frame = +3
Query: 246 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 419
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 86 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 145
Query: 420 VSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVI---DKRIYSMFESGA 590
V+WI + + + +P D Q CT KFGS ++ ++D V+ + +ESG
Sbjct: 146 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVLIGSSMNLKDYWESGE 205
Query: 591 WDV 599
W +
Sbjct: 206 WAI 208
>AF385584-1|AAK68110.1| 489|Homo sapiens nicotinic cholinergic
receptor alpha 3 protein.
Length = 489
Score = 70.5 bits (165), Expect = 7e-12
Identities = 36/123 (29%), Positives = 64/123 (52%), Gaps = 5/123 (4%)
Frame = +3
Query: 246 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 419
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 81 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 140
Query: 420 VSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVI---DKRIYSMFESGA 590
V+WI + + + +P D Q CT KFGS ++ ++D V+ + +ESG
Sbjct: 141 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVLIGSSMNLKDYWESGE 200
Query: 591 WDV 599
W +
Sbjct: 201 WAI 203
>Y16282-1|CAA76155.1| 494|Homo sapiens nicotinic acetylcholine
receptor alpha6 subunit precursor protein.
Length = 494
Score = 69.7 bits (163), Expect = 1e-11
Identities = 47/188 (25%), Positives = 88/188 (46%), Gaps = 13/188 (6%)
Frame = +3
Query: 87 CENATSLSLMIDSLLATYDRESPPDSKIVVNLTLHL-----RHANIRESESTVRILADLQ 251
C + + L + Y++ P + +T+H + AN+ E + L+
Sbjct: 28 CVGCATEERLFHKLFSHYNQFIRPVENVSDPVTVHFEVAITQLANVDEVNQIMETNLWLR 87
Query: 252 MNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNG 416
W D +L W+ E+ G T V ++++W+PD+VL N A GD+ + +A + NG
Sbjct: 88 HIWNDYKLRWDPMEYDGIETLRVPADKIWKPDIVLYNNAV---GDFQVEGKTKALLKYNG 144
Query: 417 SVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD-FVIDKRI--YSMFESG 587
++W + M + +P D Q C+ KFGS ++ E+D +I ++ +E+
Sbjct: 145 MITWTPPAIFKSSCPMDITFFPFDHQNCSLKFGSWTYDKAEIDLLIIGSKVDMNDFWENS 204
Query: 588 AWDVTDLS 611
W++ D S
Sbjct: 205 EWEIIDAS 212
>U62435-1|AAB40113.1| 494|Homo sapiens nicotinic acetylcholine
receptor alpha6 subunit precursor protein.
Length = 494
Score = 69.7 bits (163), Expect = 1e-11
Identities = 47/188 (25%), Positives = 88/188 (46%), Gaps = 13/188 (6%)
Frame = +3
Query: 87 CENATSLSLMIDSLLATYDRESPPDSKIVVNLTLHL-----RHANIRESESTVRILADLQ 251
C + + L + Y++ P + +T+H + AN+ E + L+
Sbjct: 28 CVGCATEERLFHKLFSHYNQFIRPVENVSDPVTVHFEVAITQLANVDEVNQIMETNLWLR 87
Query: 252 MNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNG 416
W D +L W+ E+ G T V ++++W+PD+VL N A GD+ + +A + NG
Sbjct: 88 HIWNDYKLRWDPMEYDGIETLRVPADKIWKPDIVLYNNAV---GDFQVEGKTKALLKYNG 144
Query: 417 SVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD-FVIDKRI--YSMFESG 587
++W + M + +P D Q C+ KFGS ++ E+D +I ++ +E+
Sbjct: 145 MITWTPPAIFKSSCPMDITFFPFDHQNCSLKFGSWTYDKAEIDLLIIGSKVDMNDFWENS 204
Query: 588 AWDVTDLS 611
W++ D S
Sbjct: 205 EWEIIDAS 212
>BC014456-1|AAH14456.1| 494|Homo sapiens cholinergic receptor,
nicotinic, alpha 6 protein.
Length = 494
Score = 69.7 bits (163), Expect = 1e-11
Identities = 47/188 (25%), Positives = 88/188 (46%), Gaps = 13/188 (6%)
Frame = +3
Query: 87 CENATSLSLMIDSLLATYDRESPPDSKIVVNLTLHL-----RHANIRESESTVRILADLQ 251
C + + L + Y++ P + +T+H + AN+ E + L+
Sbjct: 28 CVGCATEERLFHKLFSHYNQFIRPVENVSDPVTVHFEVAITQLANVDEVNQIMETNLWLR 87
Query: 252 MNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNG 416
W D +L W+ E+ G T V ++++W+PD+VL N A GD+ + +A + NG
Sbjct: 88 HIWNDYKLRWDPMEYDGIETLRVPADKIWKPDIVLYNNAV---GDFQVEGKTKALLKYNG 144
Query: 417 SVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD-FVIDKRI--YSMFESG 587
++W + M + +P D Q C+ KFGS ++ E+D +I ++ +E+
Sbjct: 145 MITWTPPAIFKSSCPMDITFFPFDHQNCSLKFGSWTYDKAEIDLLIIGSKVDMNDFWENS 204
Query: 588 AWDVTDLS 611
W++ D S
Sbjct: 205 EWEIIDAS 212
>AJ001935-1|CAA05108.1| 504|Homo sapiens CHRNB2 protein.
Length = 504
Score = 69.7 bits (163), Expect = 1e-11
Identities = 53/195 (27%), Positives = 87/195 (44%), Gaps = 7/195 (3%)
Frame = +3
Query: 45 YXFLLTCAIASAAECENATSLSLMIDSLLATYDRESPPDSKIV-VNLTLHLRHA-NIRES 218
+ L C+ A+ E L+ S R + S++V V L + L ++ E
Sbjct: 14 FGLLRLCSGVWGADTEERLVEHLLDPSRYNKLIRPATNGSELVTVQLMVSLAQLISVHER 73
Query: 219 ESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYAL 392
E + L W D RL+W E+ + S+ +W PDVVL N A +
Sbjct: 74 EQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLPDVVLYNNADGMYEVSFYS 133
Query: 393 RARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDKRIYS 572
A VS +GS+ W+ + +++ ++P D Q CT KF S ++ E+D V+ + S
Sbjct: 134 NAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRSWTYDRTEIDLVLKSEVAS 193
Query: 573 MFE---SGAWDVTDL 608
+ + SG WD+ L
Sbjct: 194 LDDFTPSGEWDIVAL 208
>AB079251-1|BAC06855.1| 494|Homo sapiens Nicotinic acetylcholine
receptor alpha 6 protein.
Length = 494
Score = 69.7 bits (163), Expect = 1e-11
Identities = 47/188 (25%), Positives = 88/188 (46%), Gaps = 13/188 (6%)
Frame = +3
Query: 87 CENATSLSLMIDSLLATYDRESPPDSKIVVNLTLHL-----RHANIRESESTVRILADLQ 251
C + + L + Y++ P + +T+H + AN+ E + L+
Sbjct: 28 CVGCATEERLFHKLFSHYNQFIRPVENVSDPVTVHFEVAITQLANVDEVNQIMETNLWLR 87
Query: 252 MNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNG 416
W D +L W+ E+ G T V ++++W+PD+VL N A GD+ + +A + NG
Sbjct: 88 HIWNDYKLRWDPMEYDGIETLRVPADKIWKPDIVLYNNAV---GDFQVEGKTKALLKYNG 144
Query: 417 SVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD-FVIDKRI--YSMFESG 587
++W + M + +P D Q C+ KFGS ++ E+D +I ++ +E+
Sbjct: 145 MITWTPPAIFKSSCPMDITFFPFDHQNCSLKFGSWTYDKAEIDLLIIGSKVDMNDFWENS 204
Query: 588 AWDVTDLS 611
W++ D S
Sbjct: 205 EWEIIDAS 212
>Y16281-1|CAA76154.1| 529|Homo sapiens nicotinic acetylcholine
receptor alpha2 subunit precursor protein.
Length = 529
Score = 69.3 bits (162), Expect = 2e-11
Identities = 41/135 (30%), Positives = 69/135 (51%), Gaps = 7/135 (5%)
Frame = +3
Query: 246 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAA-ATTAGDYALRARVSNNGS 419
L+ W D +L WN ++G T L V SE +W PD+VL N A A + +A + + G+
Sbjct: 111 LKQEWSDYKLRWNPADFGNITSLRVPSEMIWIPDIVLYNNADGEFAVTHMTKAHLFSTGT 170
Query: 420 VSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNS-----DEMDFVIDKRIYSMFES 584
V W+ + S+ + +P D Q C KFGS ++ ++M+ +D + Y +ES
Sbjct: 171 VHWVPPAIYKSSCSIDVTFFPFDQQNCKMKFGSWTYDKAKIDLEQMEQTVDLKDY--WES 228
Query: 585 GAWDVTDLSXAVXSQ 629
G W + + + S+
Sbjct: 229 GEWAIVNATGTYNSK 243
>U62431-1|AAB40109.1| 529|Homo sapiens nicotinic acetylcholine
receptor alpha2 subunit precursor protein.
Length = 529
Score = 69.3 bits (162), Expect = 2e-11
Identities = 41/135 (30%), Positives = 69/135 (51%), Gaps = 7/135 (5%)
Frame = +3
Query: 246 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAA-ATTAGDYALRARVSNNGS 419
L+ W D +L WN ++G T L V SE +W PD+VL N A A + +A + + G+
Sbjct: 111 LKQEWSDYKLRWNPADFGNITSLRVPSEMIWIPDIVLYNNADGEFAVTHMTKAHLFSTGT 170
Query: 420 VSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNS-----DEMDFVIDKRIYSMFES 584
V W+ + S+ + +P D Q C KFGS ++ ++M+ +D + Y +ES
Sbjct: 171 VHWVPPAIYKSSCSIDVTFFPFDQQNCKMKFGSWTYDKAKIDLEQMEQTVDLKDY--WES 228
Query: 585 GAWDVTDLSXAVXSQ 629
G W + + + S+
Sbjct: 229 GEWAIVNATGTYNSK 243
>Y08421-1|CAA69698.1| 627|Homo sapiens nicotinic acetylcholine
receptor alpha4 subunit precursor protein.
Length = 627
Score = 68.9 bits (161), Expect = 2e-11
Identities = 49/177 (27%), Positives = 90/177 (50%), Gaps = 13/177 (7%)
Frame = +3
Query: 114 MIDSLLATYDRESPPDSKI--VVNLTLHLRHANIRESESTVRILAD---LQMNWIDKRLS 278
++ L + Y++ S P + I VV + L A + + + +++ ++ W D +L
Sbjct: 40 LLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLR 99
Query: 279 WNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNGSVSWIKRLD 443
W+ ++ T + + SE +WRPD+VL N A GD+A+ +A + ++G V W
Sbjct: 100 WDPADYENVTSIRIPSELIWRPDIVLYNNAD---GDFAVTHLTKAHLFHDGRVQWTPPAI 156
Query: 444 ISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFV-IDKRI--YSMFESGAWDVTD 605
+ S+ + +P D Q CT KFGS ++ ++D V + R+ +ESG W + D
Sbjct: 157 YKSSCSIDVTFFPFDQQNCTMKFGSWTYDKAKIDLVNMHSRVDQLDFWESGEWVIVD 213
>Y08415-1|CAA69692.1| 502|Homo sapiens nicotinic acetylcholine
receptor beta2 subunit precursor protein.
Length = 502
Score = 68.9 bits (161), Expect = 2e-11
Identities = 44/153 (28%), Positives = 72/153 (47%), Gaps = 6/153 (3%)
Frame = +3
Query: 168 IVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 341
+ V L + L ++ E E + L W D RL+W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 342 DVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 518
DVVL N A + A VS +GS+ W+ + +++ ++P D Q CT KF S
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRS 175
Query: 519 RMHNSDEMDFVIDKRIYSMFE---SGAWDVTDL 608
++ E+D V+ + S+ + SG WD+ L
Sbjct: 176 WTYDRTEIDLVLKSEVASLDDFTPSGEWDIVAL 208
>X89741-1|CAA61893.1| 627|Homo sapiens neuronal acetylcholine
receptor alpha-4 subunit protein.
Length = 627
Score = 68.9 bits (161), Expect = 2e-11
Identities = 49/177 (27%), Positives = 90/177 (50%), Gaps = 13/177 (7%)
Frame = +3
Query: 114 MIDSLLATYDRESPPDSKI--VVNLTLHLRHANIRESESTVRILAD---LQMNWIDKRLS 278
++ L + Y++ S P + I VV + L A + + + +++ ++ W D +L
Sbjct: 40 LLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLR 99
Query: 279 WNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNGSVSWIKRLD 443
W+ ++ T + + SE +WRPD+VL N A GD+A+ +A + ++G V W
Sbjct: 100 WDPADYENVTSIRIPSELIWRPDIVLYNNAD---GDFAVTHLTKAHLFHDGRVQWTPPAI 156
Query: 444 ISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFV-IDKRI--YSMFESGAWDVTD 605
+ S+ + +P D Q CT KFGS ++ ++D V + R+ +ESG W + D
Sbjct: 157 YKSSCSIDVTFFPFDQQNCTMKFGSWTYDKAKIDLVNMHSRVDQLDFWESGEWVIVD 213
>X87629-1|CAA60959.1| 602|Homo sapiens nicotinic acetylcholine
receptor protein.
Length = 602
Score = 68.9 bits (161), Expect = 2e-11
Identities = 49/177 (27%), Positives = 90/177 (50%), Gaps = 13/177 (7%)
Frame = +3
Query: 114 MIDSLLATYDRESPPDSKI--VVNLTLHLRHANIRESESTVRILAD---LQMNWIDKRLS 278
++ L + Y++ S P + I VV + L A + + + +++ ++ W D +L
Sbjct: 15 LLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLR 74
Query: 279 WNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNGSVSWIKRLD 443
W+ ++ T + + SE +WRPD+VL N A GD+A+ +A + ++G V W
Sbjct: 75 WDPADYENVTSIRIPSELIWRPDIVLYNNAD---GDFAVTHLTKAHLFHDGRVQWTPPAI 131
Query: 444 ISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFV-IDKRI--YSMFESGAWDVTD 605
+ S+ + +P D Q CT KFGS ++ ++D V + R+ +ESG W + D
Sbjct: 132 YKSSCSIDVTFFPFDQQNCTMKFGSWTYDKAKIDLVNMHSRVDQLDFWESGEWVIVD 188
>X53179-1|CAA37320.1| 502|Homo sapiens precursor peptide (AA -25 to
477) protein.
Length = 502
Score = 68.9 bits (161), Expect = 2e-11
Identities = 44/153 (28%), Positives = 72/153 (47%), Gaps = 6/153 (3%)
Frame = +3
Query: 168 IVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 341
+ V L + L ++ E E + L W D RL+W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 342 DVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 518
DVVL N A + A VS +GS+ W+ + +++ ++P D Q CT KF S
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRS 175
Query: 519 RMHNSDEMDFVIDKRIYSMFE---SGAWDVTDL 608
++ E+D V+ + S+ + SG WD+ L
Sbjct: 176 WTYDRTEIDLVLKSEVASLDDFTPSGEWDIVAL 208
>U62437-1|AAB40115.1| 502|Homo sapiens nicotinic acetylcholine
receptor beta2 subunit precursor protein.
Length = 502
Score = 68.9 bits (161), Expect = 2e-11
Identities = 44/153 (28%), Positives = 72/153 (47%), Gaps = 6/153 (3%)
Frame = +3
Query: 168 IVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 341
+ V L + L ++ E E + L W D RL+W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 342 DVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 518
DVVL N A + A VS +GS+ W+ + +++ ++P D Q CT KF S
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRS 175
Query: 519 RMHNSDEMDFVIDKRIYSMFE---SGAWDVTDL 608
++ E+D V+ + S+ + SG WD+ L
Sbjct: 176 WTYDRTEIDLVLKSEVASLDDFTPSGEWDIVAL 208
>U62433-1|AAB40111.1| 627|Homo sapiens nicotinic acetylcholine
receptor alpha4 subunit precursor protein.
Length = 627
Score = 68.9 bits (161), Expect = 2e-11
Identities = 49/177 (27%), Positives = 90/177 (50%), Gaps = 13/177 (7%)
Frame = +3
Query: 114 MIDSLLATYDRESPPDSKI--VVNLTLHLRHANIRESESTVRILAD---LQMNWIDKRLS 278
++ L + Y++ S P + I VV + L A + + + +++ ++ W D +L
Sbjct: 40 LLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLR 99
Query: 279 WNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNGSVSWIKRLD 443
W+ ++ T + + SE +WRPD+VL N A GD+A+ +A + ++G V W
Sbjct: 100 WDPADYENVTSIRIPSELIWRPDIVLYNNAD---GDFAVTHLTKAHLFHDGRVQWTPPAI 156
Query: 444 ISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFV-IDKRI--YSMFESGAWDVTD 605
+ S+ + +P D Q CT KFGS ++ ++D V + R+ +ESG W + D
Sbjct: 157 YKSSCSIDVTFFPFDQQNCTMKFGSWTYDKAKIDLVNMHSRVDQLDFWESGEWVIVD 213
>L35901-1|AAA64743.1| 627|Homo sapiens nicotinic acetylcholine
receptor alpha 4 subunit protein.
Length = 627
Score = 68.9 bits (161), Expect = 2e-11
Identities = 49/177 (27%), Positives = 90/177 (50%), Gaps = 13/177 (7%)
Frame = +3
Query: 114 MIDSLLATYDRESPPDSKI--VVNLTLHLRHANIRESESTVRILAD---LQMNWIDKRLS 278
++ L + Y++ S P + I VV + L A + + + +++ ++ W D +L
Sbjct: 40 LLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLR 99
Query: 279 WNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNGSVSWIKRLD 443
W+ ++ T + + SE +WRPD+VL N A GD+A+ +A + ++G V W
Sbjct: 100 WDPADYENVTSIRIPSELIWRPDIVLYNNAD---GDFAVTHLTKAHLFHDGRVQWTPPAI 156
Query: 444 ISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFV-IDKRI--YSMFESGAWDVTD 605
+ S+ + +P D Q CT KFGS ++ ++D V + R+ +ESG W + D
Sbjct: 157 YKSSCSIDVTFFPFDQQNCTMKFGSWTYDKAKIDLVNMHSRVDQLDFWESGEWVIVD 213
>DQ093071-1|AAY88737.1| 627|Homo sapiens cholinergic receptor,
nicotinic, alpha polypeptide 4 protein.
Length = 627
Score = 68.9 bits (161), Expect = 2e-11
Identities = 49/177 (27%), Positives = 90/177 (50%), Gaps = 13/177 (7%)
Frame = +3
Query: 114 MIDSLLATYDRESPPDSKI--VVNLTLHLRHANIRESESTVRILAD---LQMNWIDKRLS 278
++ L + Y++ S P + I VV + L A + + + +++ ++ W D +L
Sbjct: 40 LLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLR 99
Query: 279 WNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNGSVSWIKRLD 443
W+ ++ T + + SE +WRPD+VL N A GD+A+ +A + ++G V W
Sbjct: 100 WDPADYENVTSIRIPSELIWRPDIVLYNNAD---GDFAVTHLTKAHLFHDGRVQWTPPAI 156
Query: 444 ISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFV-IDKRI--YSMFESGAWDVTD 605
+ S+ + +P D Q CT KFGS ++ ++D V + R+ +ESG W + D
Sbjct: 157 YKSSCSIDVTFFPFDQQNCTMKFGSWTYDKAKIDLVNMHSRVDQLDFWESGEWVIVD 213
>BC096290-1|AAH96290.1| 627|Homo sapiens cholinergic receptor,
nicotinic, alpha 4 protein.
Length = 627
Score = 68.9 bits (161), Expect = 2e-11
Identities = 49/177 (27%), Positives = 90/177 (50%), Gaps = 13/177 (7%)
Frame = +3
Query: 114 MIDSLLATYDRESPPDSKI--VVNLTLHLRHANIRESESTVRILAD---LQMNWIDKRLS 278
++ L + Y++ S P + I VV + L A + + + +++ ++ W D +L
Sbjct: 40 LLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLR 99
Query: 279 WNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNGSVSWIKRLD 443
W+ ++ T + + SE +WRPD+VL N A GD+A+ +A + ++G V W
Sbjct: 100 WDPADYENVTSIRIPSELIWRPDIVLYNNAD---GDFAVTHLTKAHLFHDGRVQWTPPAI 156
Query: 444 ISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFV-IDKRI--YSMFESGAWDVTD 605
+ S+ + +P D Q CT KFGS ++ ++D V + R+ +ESG W + D
Sbjct: 157 YKSSCSIDVTFFPFDQQNCTMKFGSWTYDKAKIDLVNMHSRVDQLDFWESGEWVIVD 213
>BC075041-1|AAH75041.1| 502|Homo sapiens cholinergic receptor,
nicotinic, beta 2 (neuronal) protein.
Length = 502
Score = 68.9 bits (161), Expect = 2e-11
Identities = 44/153 (28%), Positives = 72/153 (47%), Gaps = 6/153 (3%)
Frame = +3
Query: 168 IVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 341
+ V L + L ++ E E + L W D RL+W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 342 DVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 518
DVVL N A + A VS +GS+ W+ + +++ ++P D Q CT KF S
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRS 175
Query: 519 RMHNSDEMDFVIDKRIYSMFE---SGAWDVTDL 608
++ E+D V+ + S+ + SG WD+ L
Sbjct: 176 WTYDRTEIDLVLKSEVASLDDFTPSGEWDIVAL 208
>BC075040-1|AAH75040.1| 502|Homo sapiens cholinergic receptor,
nicotinic, beta 2 (neuronal) protein.
Length = 502
Score = 68.9 bits (161), Expect = 2e-11
Identities = 44/153 (28%), Positives = 72/153 (47%), Gaps = 6/153 (3%)
Frame = +3
Query: 168 IVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 341
+ V L + L ++ E E + L W D RL+W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 342 DVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 518
DVVL N A + A VS +GS+ W+ + +++ ++P D Q CT KF S
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRS 175
Query: 519 RMHNSDEMDFVIDKRIYSMFE---SGAWDVTDL 608
++ E+D V+ + S+ + SG WD+ L
Sbjct: 176 WTYDRTEIDLVLKSEVASLDDFTPSGEWDIVAL 208
>AL592078-3|CAI16184.1| 502|Homo sapiens cholinergic receptor,
nicotinic, beta 2 (neuronal) protein.
Length = 502
Score = 68.9 bits (161), Expect = 2e-11
Identities = 44/153 (28%), Positives = 72/153 (47%), Gaps = 6/153 (3%)
Frame = +3
Query: 168 IVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 341
+ V L + L ++ E E + L W D RL+W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 342 DVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 518
DVVL N A + A VS +GS+ W+ + +++ ++P D Q CT KF S
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRS 175
Query: 519 RMHNSDEMDFVIDKRIYSMFE---SGAWDVTDL 608
++ E+D V+ + S+ + SG WD+ L
Sbjct: 176 WTYDRTEIDLVLKSEVASLDDFTPSGEWDIVAL 208
>AF077186-1|AAD45422.1| 502|Homo sapiens neuronal nicotinic
acetylcholine receptor beta 2 protein.
Length = 502
Score = 68.9 bits (161), Expect = 2e-11
Identities = 44/153 (28%), Positives = 72/153 (47%), Gaps = 6/153 (3%)
Frame = +3
Query: 168 IVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 341
+ V L + L ++ E E + L W D RL+W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 342 DVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 518
DVVL N A + A VS +GS+ W+ + +++ ++P D Q CT KF S
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRS 175
Query: 519 RMHNSDEMDFVIDKRIYSMFE---SGAWDVTDL 608
++ E+D V+ + S+ + SG WD+ L
Sbjct: 176 WTYDRTEIDLVLKSEVASLDDFTPSGEWDIVAL 208
>M86383-1|AAC84176.1| 502|Homo sapiens nicotinic acetylcholine
receptor alpha 3 subunit precursor protein.
Length = 502
Score = 68.1 bits (159), Expect = 4e-11
Identities = 37/126 (29%), Positives = 66/126 (52%), Gaps = 8/126 (6%)
Frame = +3
Query: 246 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYAL----RARVSN 410
L+ W D +L WN +G + ++ V ++++W+PD+VL N A GD+ + +A +
Sbjct: 84 LKQIWNDYKLKWNPSGYGGAEFMRVPAQKIWKPDIVLYNNAV---GDFQVTTKTKALLKY 140
Query: 411 NGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVI---DKRIYSMFE 581
G V+WI + + + +P D Q CT KFGS ++ ++D V+ + +E
Sbjct: 141 TGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVLIGSSMNLKDYWE 200
Query: 582 SGAWDV 599
SG W +
Sbjct: 201 SGEWAI 206
>X14830-1|CAA32939.1| 501|Homo sapiens protein ( Human mRNA for
muscle acetylcholine receptor beta-subunit. ).
Length = 501
Score = 64.9 bits (151), Expect = 3e-10
Identities = 47/137 (34%), Positives = 70/137 (51%), Gaps = 4/137 (2%)
Frame = +3
Query: 144 RESPPDSKIVVNLTL-HLRHANIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLV 317
RE ++ V L L L N ++ E + ++ DL+ W D RLSW+ E G + +
Sbjct: 46 REVGDRVRVSVGLILAQLISLNEKDEEMSTKVYLDLE--WTDYRLSWDPAEHDGIDSLRI 103
Query: 318 SSERLWRPDVVLLNAAATTAGDYAL--RARVSNNGSVSWIKRLDISTPISMQLDNWPNDM 491
++E +W PDVVLLN D AL VS++GSV W + S+Q+ +P D
Sbjct: 104 TAESVWLPDVVLLNNNDGNF-DVALDISVVVSSDGSVRWQPPGIYRSSCSIQVTYFPFDW 162
Query: 492 QTCTFKFGSRMHNSDEM 542
Q CT F S ++S E+
Sbjct: 163 QNCTMVFSSYSYDSSEV 179
>BC011371-1|AAH11371.1| 501|Homo sapiens cholinergic receptor,
nicotinic, beta 1 (muscle) protein.
Length = 501
Score = 64.9 bits (151), Expect = 3e-10
Identities = 47/137 (34%), Positives = 70/137 (51%), Gaps = 4/137 (2%)
Frame = +3
Query: 144 RESPPDSKIVVNLTL-HLRHANIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLV 317
RE ++ V L L L N ++ E + ++ DL+ W D RLSW+ E G + +
Sbjct: 46 REVGDRVRVSVGLILAQLISLNEKDEEMSTKVYLDLE--WTDYRLSWDPAEHDGIDSLRI 103
Query: 318 SSERLWRPDVVLLNAAATTAGDYAL--RARVSNNGSVSWIKRLDISTPISMQLDNWPNDM 491
++E +W PDVVLLN D AL VS++GSV W + S+Q+ +P D
Sbjct: 104 TAESVWLPDVVLLNNNDGNF-DVALDISVVVSSDGSVRWQPPGIYRSSCSIQVTYFPFDW 162
Query: 492 QTCTFKFGSRMHNSDEM 542
Q CT F S ++S E+
Sbjct: 163 QNCTMVFSSYSYDSSEV 179
>DQ644022-1|ABG35128.1| 456|Homo sapiens 5-HT3 receptor subunit E
splice variant HTR3Ea protein.
Length = 456
Score = 64.1 bits (149), Expect = 6e-10
Identities = 36/140 (25%), Positives = 67/140 (47%), Gaps = 9/140 (6%)
Frame = +3
Query: 246 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 422
L+M W + +SWN E G + ++++ LW PD+ ++ L A VSN G +
Sbjct: 91 LEMVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEGRI 150
Query: 423 SWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDKRIYSMFES------ 584
+ K + + + ++ + +P D Q CT F S ++ D M ++K ++ + ++
Sbjct: 151 RYKKPMKVDSICNLDIFYFPFDQQNCTLTFSSFLYTVDSMLLDMEKEVWEITDASRNILQ 210
Query: 585 --GAWDVTDLSXAVXSQDRG 638
G W++ LS A RG
Sbjct: 211 THGEWELLGLSKATAKLSRG 230
>BC101183-1|AAI01184.1| 471|Homo sapiens 5-hydroxytryptamine
(serotonin) receptor 3, family member E protein.
Length = 471
Score = 64.1 bits (149), Expect = 6e-10
Identities = 36/140 (25%), Positives = 67/140 (47%), Gaps = 9/140 (6%)
Frame = +3
Query: 246 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 422
L+M W + +SWN E G + ++++ LW PD+ ++ L A VSN G +
Sbjct: 106 LEMVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEGRI 165
Query: 423 SWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDKRIYSMFES------ 584
+ K + + + ++ + +P D Q CT F S ++ D M ++K ++ + ++
Sbjct: 166 RYKKPMKVDSICNLDIFYFPFDQQNCTLTFSSFLYTVDSMLLDMEKEVWEITDASRNILQ 225
Query: 585 --GAWDVTDLSXAVXSQDRG 638
G W++ LS A RG
Sbjct: 226 THGEWELLGLSKATAKLSRG 245
>BC101182-1|AAI01183.1| 471|Homo sapiens 5-hydroxytryptamine
(serotonin) receptor 3, family member E protein.
Length = 471
Score = 64.1 bits (149), Expect = 6e-10
Identities = 36/140 (25%), Positives = 67/140 (47%), Gaps = 9/140 (6%)
Frame = +3
Query: 246 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 422
L+M W + +SWN E G + ++++ LW PD+ ++ L A VSN G +
Sbjct: 106 LEMVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEGRI 165
Query: 423 SWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDKRIYSMFES------ 584
+ K + + + ++ + +P D Q CT F S ++ D M ++K ++ + ++
Sbjct: 166 RYKKPMKVDSICNLDIFYFPFDQQNCTLTFSSFLYTVDSMLLDMEKEVWEITDASRNILQ 225
Query: 585 --GAWDVTDLSXAVXSQDRG 638
G W++ LS A RG
Sbjct: 226 THGEWELLGLSKATAKLSRG 245
>AY159813-1|AAO38167.2| 471|Homo sapiens 5-hydroxytryptamine
serotonin receptor 3E protein.
Length = 471
Score = 64.1 bits (149), Expect = 6e-10
Identities = 36/140 (25%), Positives = 67/140 (47%), Gaps = 9/140 (6%)
Frame = +3
Query: 246 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 422
L+M W + +SWN E G + ++++ LW PD+ ++ L A VSN G +
Sbjct: 106 LEMVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEGRI 165
Query: 423 SWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDKRIYSMFES------ 584
+ K + + + ++ + +P D Q CT F S ++ D M ++K ++ + ++
Sbjct: 166 RYKKPMKVDSICNLDIFYFPFDQQNCTLTFSSFLYTVDSMLLDMEKEVWEITDASRNILQ 225
Query: 585 --GAWDVTDLSXAVXSQDRG 638
G W++ LS A RG
Sbjct: 226 THGEWELLGLSKATAKLSRG 245
>BC023553-1|AAH23553.1| 501|Homo sapiens cholinergic receptor,
nicotinic, beta 1 (muscle) protein.
Length = 501
Score = 63.7 bits (148), Expect = 8e-10
Identities = 45/139 (32%), Positives = 71/139 (51%), Gaps = 6/139 (4%)
Frame = +3
Query: 144 RESPPDSKIVVNLTL-HLRHANIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLV 317
RE ++ V L L L N ++ E + ++ DL+ W D RLSW+ E G + +
Sbjct: 46 REVGDRVRVSVGLILAQLISLNEKDEEMSTKVYLDLE--WTDYRLSWDPAEHDGIDSLRI 103
Query: 318 SSERLWRPDVVLLNAAATTAGDY----ALRARVSNNGSVSWIKRLDISTPISMQLDNWPN 485
++E +W PDVVLLN G++ + VS++GSV W + S+Q+ +P
Sbjct: 104 TAESVWLPDVVLLN---NNDGNFYVALDISVVVSSDGSVRWQPPGIYRSSCSIQVTYFPF 160
Query: 486 DMQTCTFKFGSRMHNSDEM 542
D Q CT F S ++S E+
Sbjct: 161 DWQNCTMVFSSYSYDSSEV 179
>X66403-1|CAA47030.1| 493|Homo sapiens acetylcholine receptor
epsilon subunit CHRNE protein.
Length = 493
Score = 63.3 bits (147), Expect = 1e-09
Identities = 36/134 (26%), Positives = 71/134 (52%), Gaps = 3/134 (2%)
Frame = +3
Query: 156 PDSKIVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEWG-CSTWLVSSER 329
P+ + ++L + L + ++ E E T+ + ++W D RL+++ ++G T V SE
Sbjct: 45 PEDTVTISLKVTLTNLISLNEKEETLTTSVWIGIDWQDYRLNYSKDDFGGIETLRVPSEL 104
Query: 330 LWRPDVVLLNAAATTAG-DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTF 506
+W P++VL N G Y V GSV+W+ + ++++ +P D Q C+
Sbjct: 105 VWLPEIVLENNIDGQFGVAYDANVLVYEGGSVTWLPPAIYRSVCAVEVTYFPFDWQNCSL 164
Query: 507 KFGSRMHNSDEMDF 548
F S+ +N++E++F
Sbjct: 165 IFRSQTYNAEEVEF 178
>BC131799-1|AAI31800.1| 447|Homo sapiens 5-hydroxytryptamine
(serotonin) receptor 3, family member C protein.
Length = 447
Score = 63.3 bits (147), Expect = 1e-09
Identities = 37/135 (27%), Positives = 67/135 (49%), Gaps = 1/135 (0%)
Frame = +3
Query: 246 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 422
+ + W + ++WN E G + V +E LW PD+ ++ + L A +S+ G +
Sbjct: 91 MDLVWDNPFINWNPKECVGINKLTVLAENLWLPDIFIVESMDVDQTPSGLTAYISSEGRI 150
Query: 423 SWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDKRIYSMFESGAWDVT 602
+ K + +++ ++ + +P D Q CTF F S ++ D M +DK + W++T
Sbjct: 151 KYDKPMRVTSICNLDIFYFPFDQQNCTFTFSSFLYTVDSMLLGMDKEV--------WEIT 202
Query: 603 DLSXAVXSQDRGEVE 647
D S V Q +GE E
Sbjct: 203 DTSRKVI-QTQGEWE 216
>BC101185-1|AAI01186.1| 374|Homo sapiens HTR3E protein protein.
Length = 374
Score = 63.3 bits (147), Expect = 1e-09
Identities = 36/148 (24%), Positives = 70/148 (47%), Gaps = 9/148 (6%)
Frame = +3
Query: 246 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 422
L+M W + +SWN E G + ++++ LW PD+ ++ L A VSN G +
Sbjct: 20 LEMVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEGRI 79
Query: 423 SWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDKRIYSMFES------ 584
+ K + + + ++ + +P D Q CT F S ++ D M ++K ++ + ++
Sbjct: 80 RYKKPMKVDSICNLDIFYFPFDQQNCTLTFSSFLYTVDSMLLDMEKEVWEITDASRNILQ 139
Query: 585 --GAWDVTDLSXAVXSQDRGEVEARVAM 662
G W++ LS A R + R ++
Sbjct: 140 THGEWELLGLSKATAKLSRVAIRRRPSL 167
>AF105999-1|AAD24503.1| 493|Homo sapiens acetylcholine receptor
epsilon subunit protein.
Length = 493
Score = 63.3 bits (147), Expect = 1e-09
Identities = 36/134 (26%), Positives = 71/134 (52%), Gaps = 3/134 (2%)
Frame = +3
Query: 156 PDSKIVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEWG-CSTWLVSSER 329
P+ + ++L + L + ++ E E T+ + ++W D RL+++ ++G T V SE
Sbjct: 45 PEDTVTISLKVTLTNLISLNEKEETLTTSVWIGIDWQDYRLNYSKDDFGGIETLRVPSEL 104
Query: 330 LWRPDVVLLNAAATTAG-DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTF 506
+W P++VL N G Y V GSV+W+ + ++++ +P D Q C+
Sbjct: 105 VWLPEIVLENNIDGQFGVAYDANVLVYEGGSVTWLPPAIYRSVCAVEVTYFPFDWQNCSL 164
Query: 507 KFGSRMHNSDEMDF 548
F S+ +N++E++F
Sbjct: 165 IFRSQTYNAEEVEF 178
>AF459285-1|AAL66182.1| 447|Homo sapiens 5-hydroxytryptamine
receptor 3 subunit C protein.
Length = 447
Score = 62.9 bits (146), Expect = 1e-09
Identities = 37/135 (27%), Positives = 66/135 (48%), Gaps = 1/135 (0%)
Frame = +3
Query: 246 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 422
+ + W + ++WN E G + V +E LW PD+ ++ + L A +S+ G +
Sbjct: 91 MDLVWDNPFINWNPKECVGINKLTVLAENLWLPDIFIVESMDVDQTPSGLTAYISSEGRI 150
Query: 423 SWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDKRIYSMFESGAWDVT 602
+ K + +++ + + +P D Q CTF F S ++ D M +DK + W++T
Sbjct: 151 KYDKPMRVTSICKLDIFYFPFDQQNCTFTFSSFLYTVDSMLLGMDKEV--------WEIT 202
Query: 603 DLSXAVXSQDRGEVE 647
D S V Q +GE E
Sbjct: 203 DTSRKVI-QTQGEWE 216
>AY349353-1|AAQ93477.1| 456|Homo sapiens 5-HT3c1 serotonin
receptor-like protein protein.
Length = 456
Score = 62.1 bits (144), Expect = 2e-09
Identities = 36/142 (25%), Positives = 67/142 (47%), Gaps = 9/142 (6%)
Frame = +3
Query: 240 ADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNG 416
A L + W + +SWN E G + ++++ LW PD+ ++ L A VSN G
Sbjct: 89 AILDVVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEG 148
Query: 417 SVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDKRIYSMFES---- 584
+ + K + + + ++ + +P D Q CT F S ++ D M ++K ++ + ++
Sbjct: 149 RIRYKKPMKVDSICNLDIFYFPFDQQNCTLTFSSFLYTVDSMLLDMEKEVWEITDASRNI 208
Query: 585 ----GAWDVTDLSXAVXSQDRG 638
G W++ LS A RG
Sbjct: 209 LQTHGEWELLGLSKATAKLSRG 230
>AY349352-1|AAQ93476.1| 441|Homo sapiens 5-HT3c1 serotonin
receptor-like protein protein.
Length = 441
Score = 62.1 bits (144), Expect = 2e-09
Identities = 36/142 (25%), Positives = 67/142 (47%), Gaps = 9/142 (6%)
Frame = +3
Query: 240 ADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNG 416
A L + W + +SWN E G + ++++ LW PD+ ++ L A VSN G
Sbjct: 74 AILDVVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEG 133
Query: 417 SVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDKRIYSMFES---- 584
+ + K + + + ++ + +P D Q CT F S ++ D M ++K ++ + ++
Sbjct: 134 RIRYKKPMKVDSICNLDIFYFPFDQQNCTLTFSSFLYTVDSMLLDMEKEVWEITDASRNI 193
Query: 585 ----GAWDVTDLSXAVXSQDRG 638
G W++ LS A RG
Sbjct: 194 LQTHGEWELLGLSKATAKLSRG 215
>BC113575-1|AAI13576.1| 479|Homo sapiens cholinergic receptor,
nicotinic, alpha 9 protein.
Length = 479
Score = 61.7 bits (143), Expect = 3e-09
Identities = 50/201 (24%), Positives = 90/201 (44%), Gaps = 13/201 (6%)
Frame = +3
Query: 36 YSCYXFLLTCAIAS---AAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRH 200
+SC F AS AAE + + + L Y P D+ V+N+TL +
Sbjct: 5 HSCISFCWIYFAASRLRAAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQITL 64
Query: 201 ANIRESESTVRILAD---LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAA 368
+ I++ + +IL ++ W D L+W+ ++ G + + S+ +WRPD+VL N A
Sbjct: 65 SQIKDMDERNQILTAYLWIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKAD 124
Query: 369 TTAGD-YALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 545
+ + + +G ++W + + + +P D Q C FGS +N +++D
Sbjct: 125 DESSEPVNTNVVLRYDGLITWDAPAITKSSCVVDVTYFPFDNQQCNLTFGSWTYNGNQVD 184
Query: 546 F--VIDKRIYSMF-ESGAWDV 599
+D S F E W+V
Sbjct: 185 IFNALDSGDLSDFIEDVEWEV 205
>BC113549-1|AAI13550.1| 479|Homo sapiens cholinergic receptor,
nicotinic, alpha 9 protein.
Length = 479
Score = 61.7 bits (143), Expect = 3e-09
Identities = 50/201 (24%), Positives = 90/201 (44%), Gaps = 13/201 (6%)
Frame = +3
Query: 36 YSCYXFLLTCAIAS---AAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRH 200
+SC F AS AAE + + + L Y P D+ V+N+TL +
Sbjct: 5 HSCISFCWIYFAASRLRAAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQITL 64
Query: 201 ANIRESESTVRILAD---LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAA 368
+ I++ + +IL ++ W D L+W+ ++ G + + S+ +WRPD+VL N A
Sbjct: 65 SQIKDMDERNQILTAYLWIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKAD 124
Query: 369 TTAGD-YALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 545
+ + + +G ++W + + + +P D Q C FGS +N +++D
Sbjct: 125 DESSEPVNTNVVLRYDGLITWDAPAITKSSCVVDVTYFPFDNQQCNLTFGSWTYNGNQVD 184
Query: 546 F--VIDKRIYSMF-ESGAWDV 599
+D S F E W+V
Sbjct: 185 IFNALDSGDLSDFIEDVEWEV 205
>AY123244-1|AAM74523.1| 479|Homo sapiens nicotinic acetylcholine
receptor subunit alpha 9 protein.
Length = 479
Score = 61.7 bits (143), Expect = 3e-09
Identities = 50/201 (24%), Positives = 90/201 (44%), Gaps = 13/201 (6%)
Frame = +3
Query: 36 YSCYXFLLTCAIAS---AAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRH 200
+SC F AS AAE + + + L Y P D+ V+N+TL +
Sbjct: 5 HSCISFCWIYFAASRLRAAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQITL 64
Query: 201 ANIRESESTVRILAD---LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAA 368
+ I++ + +IL ++ W D L+W+ ++ G + + S+ +WRPD+VL N A
Sbjct: 65 SQIKDMDERNQILTAYLWIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKAD 124
Query: 369 TTAGD-YALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 545
+ + + +G ++W + + + +P D Q C FGS +N +++D
Sbjct: 125 DESSEPVNTNVVLRYDGLITWDAPAITKSSCVVDVTYFPFDNQQCNLTFGSWTYNGNQVD 184
Query: 546 F--VIDKRIYSMF-ESGAWDV 599
+D S F E W+V
Sbjct: 185 IFNALDSGDLSDFIEDVEWEV 205
>AJ243342-1|CAB65091.1| 479|Homo sapiens nicotinic acetylcholine
receptor alpha 9 subunit protein.
Length = 479
Score = 61.7 bits (143), Expect = 3e-09
Identities = 50/201 (24%), Positives = 90/201 (44%), Gaps = 13/201 (6%)
Frame = +3
Query: 36 YSCYXFLLTCAIAS---AAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRH 200
+SC F AS AAE + + + L Y P D+ V+N+TL +
Sbjct: 5 HSCISFCWIYFAASRLRAAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQITL 64
Query: 201 ANIRESESTVRILAD---LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAA 368
+ I++ + +IL ++ W D L+W+ ++ G + + S+ +WRPD+VL N A
Sbjct: 65 SQIKDMDERNQILTAYLWIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKAD 124
Query: 369 TTAGD-YALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 545
+ + + +G ++W + + + +P D Q C FGS +N +++D
Sbjct: 125 DESSEPVNTNVVLRYDGLITWDAPAITKSSCVVDVTYFPFDNQQCNLTFGSWTYNGNQVD 184
Query: 546 F--VIDKRIYSMF-ESGAWDV 599
+D S F E W+V
Sbjct: 185 IFNALDSGDLSDFIEDVEWEV 205
>AC118275-1|AAY40986.1| 479|Homo sapiens unknown protein.
Length = 479
Score = 61.7 bits (143), Expect = 3e-09
Identities = 50/201 (24%), Positives = 90/201 (44%), Gaps = 13/201 (6%)
Frame = +3
Query: 36 YSCYXFLLTCAIAS---AAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRH 200
+SC F AS AAE + + + L Y P D+ V+N+TL +
Sbjct: 5 HSCISFCWIYFAASRLRAAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQITL 64
Query: 201 ANIRESESTVRILAD---LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAA 368
+ I++ + +IL ++ W D L+W+ ++ G + + S+ +WRPD+VL N A
Sbjct: 65 SQIKDMDERNQILTAYLWIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKAD 124
Query: 369 TTAGD-YALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 545
+ + + +G ++W + + + +P D Q C FGS +N +++D
Sbjct: 125 DESSEPVNTNVVLRYDGLITWDAPAITKSSCVVDVTYFPFDNQQCNLTFGSWTYNGNQVD 184
Query: 546 F--VIDKRIYSMF-ESGAWDV 599
+D S F E W+V
Sbjct: 185 IFNALDSGDLSDFIEDVEWEV 205
>X01715-1|CAA25861.1| 520|Homo sapiens acetylcholine receptor gamma
chain precursor protein.
Length = 520
Score = 60.9 bits (141), Expect = 6e-09
Identities = 43/157 (27%), Positives = 75/157 (47%), Gaps = 8/157 (5%)
Frame = +3
Query: 114 MIDSLLATYDRESPPDSKI--VVNLTLHLRHANI---RESESTVRILADLQMNWIDKRLS 278
++ L+ YD P + VVN++L L N+ E E + ++M W D RL
Sbjct: 32 LLADLMQNYDPNLRPAERDSDVVNVSLKLTLTNLISLNEREEALTTNVWIEMQWCDYRLR 91
Query: 279 WNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARV--SNNGSVSWIKRLDIS 449
W+ ++ G V S +WRPD+VL N + AL V S +G + W+
Sbjct: 92 WDPRDYEGLWVLRVPSTMVWRPDIVLENNVDGVF-EVALYCNVLVSPDGCIYWLPPAIFR 150
Query: 450 TPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDK 560
+ S+ + +P D Q C+ F S+ ++++E+D + +
Sbjct: 151 SACSISVTYFPFDWQNCSLIFQSQTYSTNEIDLQLSQ 187
>AC092165-3|AAY24103.1| 520|Homo sapiens unknown protein.
Length = 520
Score = 60.9 bits (141), Expect = 6e-09
Identities = 43/157 (27%), Positives = 75/157 (47%), Gaps = 8/157 (5%)
Frame = +3
Query: 114 MIDSLLATYDRESPPDSKI--VVNLTLHLRHANI---RESESTVRILADLQMNWIDKRLS 278
++ L+ YD P + VVN++L L N+ E E + ++M W D RL
Sbjct: 32 LLADLMQNYDPNLRPAERDSDVVNVSLKLTLTNLISLNEREEALTTNVWIEMQWCDYRLR 91
Query: 279 WNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARV--SNNGSVSWIKRLDIS 449
W+ ++ G V S +WRPD+VL N + AL V S +G + W+
Sbjct: 92 WDPRDYEGLWVLRVPSTMVWRPDIVLENNVDGVF-EVALYCNVLVSPDGCIYWLPPAIFR 150
Query: 450 TPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDK 560
+ S+ + +P D Q C+ F S+ ++++E+D + +
Sbjct: 151 SACSISVTYFPFDWQNCSLIFQSQTYSTNEIDLQLSQ 187
>Y00762-1|CAA68731.1| 457|Homo sapiens protein ( Human mRNA for
muscle acetylcholine receptor alpha-subunit. ).
Length = 457
Score = 60.5 bits (140), Expect = 7e-09
Identities = 50/200 (25%), Positives = 91/200 (45%), Gaps = 13/200 (6%)
Frame = +3
Query: 45 YXFLLTCAIASAAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHA---NI 209
+ LL ++ SA + + ++ L Y P D + VV +T+ L+ N+
Sbjct: 4 WPLLLLFSLCSAGLVLGSEHETRLVAKLFKDYSSVVRPVEDHRQVVEVTVGLQLIQLINV 63
Query: 210 RESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDY 386
E V L+ W+D L WN ++G + + SE++WRPD+VL N A GD+
Sbjct: 64 DEVNQIVTTNVRLKQQWVDYNLKWNPDDYGGVKKIHIPSEKIWRPDLVLYNNA---DGDF 120
Query: 387 AL----RARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSD--EMDF 548
A+ + + G ++W + + + ++P D Q C+ K G+ ++ ++
Sbjct: 121 AIVKFTKVLLQYTGHITWTPPAIFKSYCEIIVTHFPFDEQNCSMKLGTWTYDGSVVAINP 180
Query: 549 VIDKRIYSMF-ESGAWDVTD 605
D+ S F ESG W + +
Sbjct: 181 ESDQPDLSNFMESGEWVIKE 200
>X02502-1|CAA26344.1| 457|Homo sapiens acetylcholine receptor
protein.
Length = 457
Score = 60.5 bits (140), Expect = 7e-09
Identities = 50/200 (25%), Positives = 91/200 (45%), Gaps = 13/200 (6%)
Frame = +3
Query: 45 YXFLLTCAIASAAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHA---NI 209
+ LL ++ SA + + ++ L Y P D + VV +T+ L+ N+
Sbjct: 4 WPLLLLFSLCSAGLVLGSEHETRLVAKLFKDYSSVVRPVEDHRQVVEVTVGLQLIQLINV 63
Query: 210 RESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDY 386
E V L+ W+D L WN ++G + + SE++WRPD+VL N A GD+
Sbjct: 64 DEVNQIVTTNVRLKQQWVDYNLKWNPDDYGGVKKIHIPSEKIWRPDLVLYNNA---DGDF 120
Query: 387 AL----RARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSD--EMDF 548
A+ + + G ++W + + + ++P D Q C+ K G+ ++ ++
Sbjct: 121 AIVKFTKVLLQYTGHITWTPPAIFKSYCEIIVTHFPFDEQNCSMKLGTWTYDGSVVAINP 180
Query: 549 VIDKRIYSMF-ESGAWDVTD 605
D+ S F ESG W + +
Sbjct: 181 ESDQPDLSNFMESGEWVIKE 200
>S77094-1|AAD14247.1| 457|Homo sapiens nicotinic acetylcholine
receptor alpha subunit|AChR protein.
Length = 457
Score = 60.5 bits (140), Expect = 7e-09
Identities = 50/200 (25%), Positives = 91/200 (45%), Gaps = 13/200 (6%)
Frame = +3
Query: 45 YXFLLTCAIASAAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHA---NI 209
+ LL ++ SA + + ++ L Y P D + VV +T+ L+ N+
Sbjct: 4 WPLLLLFSLCSAGLVLGSEHETRLVAKLFKDYSSVVRPVEDHRQVVEVTVGLQLIQLINV 63
Query: 210 RESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDY 386
E V L+ W+D L WN ++G + + SE++WRPD+VL N A GD+
Sbjct: 64 DEVNQIVTTNVRLKQQWVDYNLKWNPDDYGGVKKIHIPSEKIWRPDLVLYNNA---DGDF 120
Query: 387 AL----RARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSD--EMDF 548
A+ + + G ++W + + + ++P D Q C+ K G+ ++ ++
Sbjct: 121 AIVKFTKVLLQYTGHITWTPPAIFKSYCEIIVTHFPFDEQNCSMKLGTWTYDGSVVAINP 180
Query: 549 VIDKRIYSMF-ESGAWDVTD 605
D+ S F ESG W + +
Sbjct: 181 ESDQPDLSNFMESGEWVIKE 200
>BC006314-1|AAH06314.1| 269|Homo sapiens CHRNA1 protein protein.
Length = 269
Score = 60.5 bits (140), Expect = 7e-09
Identities = 50/200 (25%), Positives = 91/200 (45%), Gaps = 13/200 (6%)
Frame = +3
Query: 45 YXFLLTCAIASAAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHA---NI 209
+ LL ++ SA + + ++ L Y P D + VV +T+ L+ N+
Sbjct: 4 WPLLLLFSLCSAGLVLGSEHETRLVAKLFKDYSSVVRPVEDHRQVVEVTVGLQLIQLINV 63
Query: 210 RESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDY 386
E V L+ W+D L WN ++G + + SE++WRPD+VL N A GD+
Sbjct: 64 DEVNQIVTTNVRLKQQWVDYNLKWNPDDYGGVKKIHIPSEKIWRPDLVLYNNA---DGDF 120
Query: 387 AL----RARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSD--EMDF 548
A+ + + G ++W + + + ++P D Q C+ K G+ ++ ++
Sbjct: 121 AIVKFTKVLLQYTGHITWTPPAIFKSYCEIIVTHFPFDEQNCSMKLGTWTYDGSVVAINP 180
Query: 549 VIDKRIYSMF-ESGAWDVTD 605
D+ S F ESG W + +
Sbjct: 181 ESDQPDLSNFMESGEWVIKE 200
>AF227732-1|AAF61920.1| 470|Homo sapiens nicotinic acetylcholine
receptor alpha 9 subunit protein.
Length = 470
Score = 60.5 bits (140), Expect = 7e-09
Identities = 45/184 (24%), Positives = 84/184 (45%), Gaps = 10/184 (5%)
Frame = +3
Query: 78 AAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHANIRESESTVRILAD-- 245
AAE + + + L Y P D+ V+N+TL + + I++ + +IL
Sbjct: 16 AAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQITLSQIKDMDERNQILTAYL 75
Query: 246 -LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGD-YALRARVSNNG 416
++ W D L+W+ ++ G + + S+ +WRPD+VL N A + + + +G
Sbjct: 76 WIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKADDESSEPVNTNVVLRYDG 135
Query: 417 SVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDF--VIDKRIYSMF-ESG 587
++W + + + +P D Q C FGS +N +++D +D S F E
Sbjct: 136 LITWDAPAITKSSCVVDVTYFPFDNQQCNLTFGSWTYNGNQVDIFNALDSGDLSDFIEDV 195
Query: 588 AWDV 599
W+V
Sbjct: 196 EWEV 199
>AC018890-1|AAY14687.1| 457|Homo sapiens unknown protein.
Length = 457
Score = 60.5 bits (140), Expect = 7e-09
Identities = 50/200 (25%), Positives = 91/200 (45%), Gaps = 13/200 (6%)
Frame = +3
Query: 45 YXFLLTCAIASAAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHA---NI 209
+ LL ++ SA + + ++ L Y P D + VV +T+ L+ N+
Sbjct: 4 WPLLLLFSLCSAGLVLGSEHETRLVAKLFKDYSSVVRPVEDHRQVVEVTVGLQLIQLINV 63
Query: 210 RESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDY 386
E V L+ W+D L WN ++G + + SE++WRPD+VL N A GD+
Sbjct: 64 DEVNQIVTTNVRLKQQWVDYNLKWNPDDYGGVKKIHIPSEKIWRPDLVLYNNA---DGDF 120
Query: 387 AL----RARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSD--EMDF 548
A+ + + G ++W + + + ++P D Q C+ K G+ ++ ++
Sbjct: 121 AIVKFTKVLLQYTGHITWTPPAIFKSYCEIIVTHFPFDEQNCSMKLGTWTYDGSVVAINP 180
Query: 549 VIDKRIYSMF-ESGAWDVTD 605
D+ S F ESG W + +
Sbjct: 181 ESDQPDLSNFMESGEWVIKE 200
>AJ295237-1|CAC16144.1| 450|Homo sapiens neuronal nicotinic
acetylcholine receptor subunit4 protein.
Length = 450
Score = 58.4 bits (135), Expect = 3e-08
Identities = 45/165 (27%), Positives = 73/165 (44%), Gaps = 10/165 (6%)
Frame = +3
Query: 81 AEC---ENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHANIRESESTVRILAD 245
AEC E +L L D L A Y P D+ +N+TL + + I + + ++L
Sbjct: 20 AECLGAEGRLALKLFRD-LFANYTSALRPVADTDQTLNVTLEVTLSQIIDMDERNQVLTL 78
Query: 246 ---LQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSN 410
++ W D L W+ +G + S +WRPD+VL N A A G + + +
Sbjct: 79 YLWIRQEWTDAYLRWDPNAYGGLDAIRIPSSLVWRPDIVLYNKADAQPPGSASTNVVLRH 138
Query: 411 NGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 545
+G+V W + + + +P D Q C FGS H ++D
Sbjct: 139 DGAVRWDAPAITRSSCRVDVAAFPFDAQHCGLTFGSWTHGGHQLD 183
>AJ278118-1|CAC20435.1| 450|Homo sapiens neuronal nicotinic
acetylcholine alpha10 subunit protein.
Length = 450
Score = 58.4 bits (135), Expect = 3e-08
Identities = 45/165 (27%), Positives = 73/165 (44%), Gaps = 10/165 (6%)
Frame = +3
Query: 81 AEC---ENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHANIRESESTVRILAD 245
AEC E +L L D L A Y P D+ +N+TL + + I + + ++L
Sbjct: 20 AECLGAEGRLALKLFRD-LFANYTSALRPVADTDQTLNVTLEVTLSQIIDMDERNQVLTL 78
Query: 246 ---LQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSN 410
++ W D L W+ +G + S +WRPD+VL N A A G + + +
Sbjct: 79 YLWIRQEWTDAYLRWDPNAYGGLDAIRIPSSLVWRPDIVLYNKADAQPPGSASTNVVLRH 138
Query: 411 NGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 545
+G+V W + + + +P D Q C FGS H ++D
Sbjct: 139 DGAVRWDAPAITRSSCRVDVAAFPFDAQHCGLTFGSWTHGGHQLD 183
>AF327367-1|AAK14333.1| 450|Homo sapiens nicotinic acetylcholine
receptor subunit alpha 10 protein.
Length = 450
Score = 58.4 bits (135), Expect = 3e-08
Identities = 45/165 (27%), Positives = 73/165 (44%), Gaps = 10/165 (6%)
Frame = +3
Query: 81 AEC---ENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHANIRESESTVRILAD 245
AEC E +L L D L A Y P D+ +N+TL + + I + + ++L
Sbjct: 20 AECLGAEGRLALKLFRD-LFANYTSALRPVADTDQTLNVTLEVTLSQIIDMDERNQVLTL 78
Query: 246 ---LQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSN 410
++ W D L W+ +G + S +WRPD+VL N A A G + + +
Sbjct: 79 YLWIRQEWTDAYLRWDPNAYGGLDAIRIPSSLVWRPDIVLYNKADAQPPGSASTNVVLRH 138
Query: 411 NGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 545
+G+V W + + + +P D Q C FGS H ++D
Sbjct: 139 DGAVRWDAPAITRSSCRVDVAAFPFDAQHCGLTFGSWTHGGHQLD 183
>AF199235-1|AAG00795.2| 450|Homo sapiens nicotinic acetylcholine
receptor subunit alpha 10 protein.
Length = 450
Score = 58.4 bits (135), Expect = 3e-08
Identities = 45/165 (27%), Positives = 73/165 (44%), Gaps = 10/165 (6%)
Frame = +3
Query: 81 AEC---ENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHANIRESESTVRILAD 245
AEC E +L L D L A Y P D+ +N+TL + + I + + ++L
Sbjct: 20 AECLGAEGRLALKLFRD-LFANYTSALRPVADTDQTLNVTLEVTLSQIIDMDERNQVLTL 78
Query: 246 ---LQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSN 410
++ W D L W+ +G + S +WRPD+VL N A A G + + +
Sbjct: 79 YLWIRQEWTDAYLRWDPNAYGGLDAIRIPSSLVWRPDIVLYNKADAQPPGSASTNVVLRH 138
Query: 411 NGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 545
+G+V W + + + +P D Q C FGS H ++D
Sbjct: 139 DGAVRWDAPAITRSSCRVDVAAFPFDAQHCGLTFGSWTHGGHQLD 183
>S77554-1|AAB33983.1| 474|Homo sapiens GABAA receptor beta 2
subunit protein.
Length = 474
Score = 58.0 bits (134), Expect = 4e-08
Identities = 44/182 (24%), Positives = 80/182 (43%), Gaps = 10/182 (5%)
Frame = +3
Query: 33 YYSCYXFLLTCAIASAAECENATSLSLM---IDSLLATYDRESPPD---SKIVVNLTLHL 194
Y+ + F L A A + +++SL+ +D LL YD PD + V + + +
Sbjct: 9 YFGIWSFPLIIAAVCAQSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDI 68
Query: 195 RHAN-IRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAAT 371
+ + E + Q W DKRLS+N + +++LW PD LN +
Sbjct: 69 ASIDMVSEVNMDYTLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLNDKKS 128
Query: 372 TAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEM 542
++ R+ +G+V + R+ + M L +P D Q CT + S + +D++
Sbjct: 129 FVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDI 188
Query: 543 DF 548
+F
Sbjct: 189 EF 190
>S77553-1|AAB33982.1| 512|Homo sapiens GABAA receptor beta 2
subunit protein.
Length = 512
Score = 58.0 bits (134), Expect = 4e-08
Identities = 44/182 (24%), Positives = 80/182 (43%), Gaps = 10/182 (5%)
Frame = +3
Query: 33 YYSCYXFLLTCAIASAAECENATSLSLM---IDSLLATYDRESPPD---SKIVVNLTLHL 194
Y+ + F L A A + +++SL+ +D LL YD PD + V + + +
Sbjct: 9 YFGIWSFPLIIAAVCAQSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDI 68
Query: 195 RHAN-IRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAAT 371
+ + E + Q W DKRLS+N + +++LW PD LN +
Sbjct: 69 ASIDMVSEVNMDYTLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLNDKKS 128
Query: 372 TAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEM 542
++ R+ +G+V + R+ + M L +P D Q CT + S + +D++
Sbjct: 129 FVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDI 188
Query: 543 DF 548
+F
Sbjct: 189 EF 190
>S67368-1|AAB29370.1| 474|Homo sapiens gamma-aminobutyric acid A
receptor beta 2 subunit protein.
Length = 474
Score = 58.0 bits (134), Expect = 4e-08
Identities = 44/182 (24%), Positives = 80/182 (43%), Gaps = 10/182 (5%)
Frame = +3
Query: 33 YYSCYXFLLTCAIASAAECENATSLSLM---IDSLLATYDRESPPD---SKIVVNLTLHL 194
Y+ + F L A A + +++SL+ +D LL YD PD + V + + +
Sbjct: 9 YFGIWSFPLIIAAVCAQSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDI 68
Query: 195 RHAN-IRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAAT 371
+ + E + Q W DKRLS+N + +++LW PD LN +
Sbjct: 69 ASIDMVSEVNMDYTLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLNDKKS 128
Query: 372 TAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEM 542
++ R+ +G+V + R+ + M L +P D Q CT + S + +D++
Sbjct: 129 FVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDI 188
Query: 543 DF 548
+F
Sbjct: 189 EF 190
>BC105639-1|AAI05640.1| 474|Homo sapiens GABRB2 protein protein.
Length = 474
Score = 58.0 bits (134), Expect = 4e-08
Identities = 44/182 (24%), Positives = 80/182 (43%), Gaps = 10/182 (5%)
Frame = +3
Query: 33 YYSCYXFLLTCAIASAAECENATSLSLM---IDSLLATYDRESPPD---SKIVVNLTLHL 194
Y+ + F L A A + +++SL+ +D LL YD PD + V + + +
Sbjct: 9 YFGIWSFPLIIAAVCAQSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDI 68
Query: 195 RHAN-IRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAAT 371
+ + E + Q W DKRLS+N + +++LW PD LN +
Sbjct: 69 ASIDMVSEVNMDYTLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLNDKKS 128
Query: 372 TAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEM 542
++ R+ +G+V + R+ + M L +P D Q CT + S + +D++
Sbjct: 129 FVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDI 188
Query: 543 DF 548
+F
Sbjct: 189 EF 190
>BC099719-1|AAH99719.1| 474|Homo sapiens GABRB2 protein protein.
Length = 474
Score = 58.0 bits (134), Expect = 4e-08
Identities = 44/182 (24%), Positives = 80/182 (43%), Gaps = 10/182 (5%)
Frame = +3
Query: 33 YYSCYXFLLTCAIASAAECENATSLSLM---IDSLLATYDRESPPD---SKIVVNLTLHL 194
Y+ + F L A A + +++SL+ +D LL YD PD + V + + +
Sbjct: 9 YFGIWSFPLIIAAVCAQSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDI 68
Query: 195 RHAN-IRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAAT 371
+ + E + Q W DKRLS+N + +++LW PD LN +
Sbjct: 69 ASIDMVSEVNMDYTLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLNDKKS 128
Query: 372 TAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEM 542
++ R+ +G+V + R+ + M L +P D Q CT + S + +D++
Sbjct: 129 FVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDI 188
Query: 543 DF 548
+F
Sbjct: 189 EF 190
>BC099705-1|AAH99705.1| 474|Homo sapiens GABRB2 protein protein.
Length = 474
Score = 58.0 bits (134), Expect = 4e-08
Identities = 44/182 (24%), Positives = 80/182 (43%), Gaps = 10/182 (5%)
Frame = +3
Query: 33 YYSCYXFLLTCAIASAAECENATSLSLM---IDSLLATYDRESPPD---SKIVVNLTLHL 194
Y+ + F L A A + +++SL+ +D LL YD PD + V + + +
Sbjct: 9 YFGIWSFPLIIAAVCAQSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDI 68
Query: 195 RHAN-IRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAAT 371
+ + E + Q W DKRLS+N + +++LW PD LN +
Sbjct: 69 ASIDMVSEVNMDYTLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLNDKKS 128
Query: 372 TAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEM 542
++ R+ +G+V + R+ + M L +P D Q CT + S + +D++
Sbjct: 129 FVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDI 188
Query: 543 DF 548
+F
Sbjct: 189 EF 190
>Z23141-1|CAA80672.1| 479|Homo sapiens cholinergic receptor,
nicotinic, alpha polypeptide 7 protein.
Length = 479
Score = 56.4 bits (130), Expect = 1e-07
Identities = 32/124 (25%), Positives = 58/124 (46%), Gaps = 3/124 (2%)
Frame = +3
Query: 246 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSNNGS 419
LQM+W D L WN E+ G T ++W+PD++L N+A + V+++G
Sbjct: 55 LQMSWTDHYLQWNVSEYPGVKTVRFPDGQIWKPDILLYNSADERFDATFHTNVLVNSSGH 114
Query: 420 VSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDKR-IYSMFESGAWD 596
++ + + + +P D+Q C KFGS + +D + + I +G WD
Sbjct: 115 CQYLPPGIFKSSCYIDVRWFPFDVQHCKLKFGSWSYGGWSLDLQMQEADISGYIPNGEWD 174
Query: 597 VTDL 608
+ +
Sbjct: 175 LVGI 178
>Y08420-1|CAA69697.1| 502|Homo sapiens nicotinic acetylcholine
receptor alpha7 subunit precursor protein.
Length = 502
Score = 56.4 bits (130), Expect = 1e-07
Identities = 32/124 (25%), Positives = 58/124 (46%), Gaps = 3/124 (2%)
Frame = +3
Query: 246 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSNNGS 419
LQM+W D L WN E+ G T ++W+PD++L N+A + V+++G
Sbjct: 78 LQMSWTDHYLQWNVSEYPGVKTVRFPDGQIWKPDILLYNSADERFDATFHTNVLVNSSGH 137
Query: 420 VSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDKR-IYSMFESGAWD 596
++ + + + +P D+Q C KFGS + +D + + I +G WD
Sbjct: 138 CQYLPPGIFKSSCYIDVRWFPFDVQHCKLKFGSWSYGGWSLDLQMQEADISGYIPNGEWD 197
Query: 597 VTDL 608
+ +
Sbjct: 198 LVGI 201
>X70297-1|CAA49778.1| 502|Homo sapiens neuronal nicotinic
acetylocholine receptor alpha-7 subunit protein.
Length = 502
Score = 56.4 bits (130), Expect = 1e-07
Identities = 32/124 (25%), Positives = 58/124 (46%), Gaps = 3/124 (2%)
Frame = +3
Query: 246 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSNNGS 419
LQM+W D L WN E+ G T ++W+PD++L N+A + V+++G
Sbjct: 78 LQMSWTDHYLQWNVSEYPGVKTVRFPDGQIWKPDILLYNSADERFDATFHTNVLVNSSGH 137
Query: 420 VSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDKR-IYSMFESGAWD 596
++ + + + +P D+Q C KFGS + +D + + I +G WD
Sbjct: 138 CQYLPPGIFKSSCYIDVRWFPFDVQHCKLKFGSWSYGGWSLDLQMQEADISGYIPNGEWD 197
Query: 597 VTDL 608
+ +
Sbjct: 198 LVGI 201
>X55019-1|CAA38759.1| 517|Homo sapiens acetylcholine receptor delta
subunit protein.
Length = 517
Score = 56.4 bits (130), Expect = 1e-07
Identities = 38/142 (26%), Positives = 67/142 (47%), Gaps = 7/142 (4%)
Frame = +3
Query: 138 YDRESPP----DSKIVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEWG- 299
Y++E P + + V L L L + +++E E T+ ++ W D RL WNA E+G
Sbjct: 38 YNKELRPVAHKEESVDVALALTLSNLISLKEVEETLTTNVWIEHGWTDNRLKWNAEEFGN 97
Query: 300 CSTWLVSSERLWRPDVVL-LNAAATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDN 476
S + + +W P++VL N + Y+ V + G V W+ + + +
Sbjct: 98 ISVLRLPPDMVWLPEIVLENNNDGSFQISYSCNVLVYHYGFVYWLPPAIFRSSCPISVTY 157
Query: 477 WPNDMQTCTFKFGSRMHNSDEM 542
+P D Q C+ KF S + + E+
Sbjct: 158 FPFDWQNCSLKFSSLKYTAKEI 179
>U62436-1|AAB40114.1| 502|Homo sapiens nicotinic acetylcholine
receptor alpha7 subunit precursor protein.
Length = 502
Score = 56.4 bits (130), Expect = 1e-07
Identities = 32/124 (25%), Positives = 58/124 (46%), Gaps = 3/124 (2%)
Frame = +3
Query: 246 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSNNGS 419
LQM+W D L WN E+ G T ++W+PD++L N+A + V+++G
Sbjct: 78 LQMSWTDHYLQWNVSEYPGVKTVRFPDGQIWKPDILLYNSADERFDATFHTNVLVNSSGH 137
Query: 420 VSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDKR-IYSMFESGAWD 596
++ + + + +P D+Q C KFGS + +D + + I +G WD
Sbjct: 138 CQYLPPGIFKSSCYIDVRWFPFDVQHCKLKFGSWSYGGWSLDLQMQEADISGYIPNGEWD 197
Query: 597 VTDL 608
+ +
Sbjct: 198 LVGI 201
>BC093925-1|AAH93925.1| 517|Homo sapiens cholinergic receptor,
nicotinic, delta protein.
Length = 517
Score = 56.4 bits (130), Expect = 1e-07
Identities = 38/142 (26%), Positives = 67/142 (47%), Gaps = 7/142 (4%)
Frame = +3
Query: 138 YDRESPP----DSKIVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEWG- 299
Y++E P + + V L L L + +++E E T+ ++ W D RL WNA E+G
Sbjct: 38 YNKELRPVAHKEESVDVALALTLSNLISLKEVEETLTTNVWIEHGWTDNRLKWNAEEFGN 97
Query: 300 CSTWLVSSERLWRPDVVL-LNAAATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDN 476
S + + +W P++VL N + Y+ V + G V W+ + + +
Sbjct: 98 ISVLRLPPDMVWLPEIVLENNNDGSFQISYSCNVLVYHYGFVYWLPPAIFRSSCPISVTY 157
Query: 477 WPNDMQTCTFKFGSRMHNSDEM 542
+P D Q C+ KF S + + E+
Sbjct: 158 FPFDWQNCSLKFSSLKYTAKEI 179
>BC093923-1|AAH93923.1| 517|Homo sapiens cholinergic receptor,
nicotinic, delta protein.
Length = 517
Score = 56.4 bits (130), Expect = 1e-07
Identities = 38/142 (26%), Positives = 67/142 (47%), Gaps = 7/142 (4%)
Frame = +3
Query: 138 YDRESPP----DSKIVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEWG- 299
Y++E P + + V L L L + +++E E T+ ++ W D RL WNA E+G
Sbjct: 38 YNKELRPVAHKEESVDVALALTLSNLISLKEVEETLTTNVWIEHGWTDNRLKWNAEEFGN 97
Query: 300 CSTWLVSSERLWRPDVVL-LNAAATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDN 476
S + + +W P++VL N + Y+ V + G V W+ + + +
Sbjct: 98 ISVLRLPPDMVWLPEIVLENNNDGSFQISYSCNVLVYHYGFVYWLPPAIFRSSCPISVTY 157
Query: 477 WPNDMQTCTFKFGSRMHNSDEM 542
+P D Q C+ KF S + + E+
Sbjct: 158 FPFDWQNCSLKFSSLKYTAKEI 179
>AJ586911-1|CAE52911.1| 502|Homo sapiens nicotinic acetylcholine
alpha-7 subunit protein.
Length = 502
Score = 56.4 bits (130), Expect = 1e-07
Identities = 32/124 (25%), Positives = 58/124 (46%), Gaps = 3/124 (2%)
Frame = +3
Query: 246 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSNNGS 419
LQM+W D L WN E+ G T ++W+PD++L N+A + V+++G
Sbjct: 78 LQMSWTDHYLQWNVSEYPGVKTVRFPDGQIWKPDILLYNSADERFDATFHTNVLVNSSGH 137
Query: 420 VSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDKR-IYSMFESGAWD 596
++ + + + +P D+Q C KFGS + +D + + I +G WD
Sbjct: 138 CQYLPPGIFKSSCYIDVRWFPFDVQHCKLKFGSWSYGGWSLDLQMQEADISGYIPNGEWD 197
Query: 597 VTDL 608
+ +
Sbjct: 198 LVGI 201
>AC092165-2|AAY24102.1| 517|Homo sapiens unknown protein.
Length = 517
Score = 56.4 bits (130), Expect = 1e-07
Identities = 38/142 (26%), Positives = 67/142 (47%), Gaps = 7/142 (4%)
Frame = +3
Query: 138 YDRESPP----DSKIVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEWG- 299
Y++E P + + V L L L + +++E E T+ ++ W D RL WNA E+G
Sbjct: 38 YNKELRPVAHKEESVDVALALTLSNLISLKEVEETLTTNVWIEHGWTDNRLKWNAEEFGN 97
Query: 300 CSTWLVSSERLWRPDVVL-LNAAATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDN 476
S + + +W P++VL N + Y+ V + G V W+ + + +
Sbjct: 98 ISVLRLPPDMVWLPEIVLENNNDGSFQISYSCNVLVYHYGFVYWLPPAIFRSSCPISVTY 157
Query: 477 WPNDMQTCTFKFGSRMHNSDEM 542
+P D Q C+ KF S + + E+
Sbjct: 158 FPFDWQNCSLKFSSLKYTAKEI 179
>U40583-1|AAA83561.1| 502|Homo sapiens alpha 7 neuronal nicotinic
acetylcholine receptor protein.
Length = 502
Score = 55.2 bits (127), Expect = 3e-07
Identities = 32/124 (25%), Positives = 57/124 (45%), Gaps = 3/124 (2%)
Frame = +3
Query: 246 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSNNGS 419
LQM+W D L WN E+ G T ++W+PD++L N+A + V+ +G
Sbjct: 78 LQMSWTDHYLQWNVSEYPGVKTVRFPDGQIWKPDILLYNSADERFDATFHTNVLVNPSGH 137
Query: 420 VSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDKR-IYSMFESGAWD 596
++ + + + +P D+Q C KFGS + +D + + I +G WD
Sbjct: 138 CQYLPPGIFKSSCYIDVRWFPFDVQHCKLKFGSWSYGGWSLDLQMQEADISGYIPNGEWD 197
Query: 597 VTDL 608
+ +
Sbjct: 198 LVGI 201
>AF385585-1|AAK68111.1| 502|Homo sapiens nicotinic cholinergic
receptor alpha 7 protein.
Length = 502
Score = 55.2 bits (127), Expect = 3e-07
Identities = 32/124 (25%), Positives = 57/124 (45%), Gaps = 3/124 (2%)
Frame = +3
Query: 246 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSNNGS 419
LQM+W D L WN E+ G T ++W+PD++L N+A + V+ +G
Sbjct: 78 LQMSWTDHYLQWNVSEYPGVKTVRFPDGQIWKPDILLYNSADERFDATFHTNVLVNPSGH 137
Query: 420 VSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDKR-IYSMFESGAWD 596
++ + + + +P D+Q C KFGS + +D + + I +G WD
Sbjct: 138 CQYLPPGIFKSSCYIDVRWFPFDVQHCKLKFGSWSYGGWSLDLQMQEADISGYIPNGEWD 197
Query: 597 VTDL 608
+ +
Sbjct: 198 LVGI 201
>BC110597-1|AAI10598.1| 411|Homo sapiens ligand-gated ion channel,
zinc activated 1 protein.
Length = 411
Score = 54.4 bits (125), Expect = 5e-07
Identities = 28/101 (27%), Positives = 49/101 (48%)
Frame = +3
Query: 246 LQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVS 425
L+++W+D RL+WN + E LW P + +L A D + +ARV +G V
Sbjct: 86 LRLSWLDTRLAWNTSAHPRHAITLPWESLWTPRLTILEALWVDWRDQSPQARVDQDGHVK 145
Query: 426 WIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDF 548
L T + +L ++P D C+ F + + + E++F
Sbjct: 146 LNLALTTETNCNFELLHFPRDHSNCSLSFYALSNTAMELEF 186
>AF512521-1|AAO20969.1| 411|Homo sapiens ligand-gated ion channel
subunit protein.
Length = 411
Score = 54.4 bits (125), Expect = 5e-07
Identities = 28/101 (27%), Positives = 49/101 (48%)
Frame = +3
Query: 246 LQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVS 425
L+++W+D RL+WN + E LW P + +L A D + +ARV +G V
Sbjct: 86 LRLSWLDTRLAWNTSAHPRHAITLPWESLWTPRLTILEALWVDWRDQSPQARVDQDGHVK 145
Query: 426 WIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDF 548
L T + +L ++P D C+ F + + + E++F
Sbjct: 146 LNLALTTETNCNFELLHFPRDHSNCSLSFYALSNTAMELEF 186
>L08485-1|AAA58490.1| 462|Homo sapiens GABA-benzodiazepine receptor
alpha-5-subunit protein.
Length = 462
Score = 54.0 bits (124), Expect = 6e-07
Identities = 39/161 (24%), Positives = 73/161 (45%), Gaps = 7/161 (4%)
Frame = +3
Query: 90 ENATSLSLMIDSLLATYDRESPPD--SKIV-VNLTLHLRHAN-IRESESTVRILADLQMN 257
+N T + ++D LL YD P +I V +++ + ++E I + +
Sbjct: 44 DNITIFTRILDGLLDGYDNRLRPGLGERITQVRTDIYVTSFGPVSDTEMEYTIDVFFRQS 103
Query: 258 WIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSW 428
W D+RL + + + ++W PD N + A + R+ ++G++ +
Sbjct: 104 WKDERLRFKGPMQRLPLNNLLASKIWTPDTFFHNGKKSIAHNMTTPNKLLRLEDDGTLLY 163
Query: 429 IKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFV 551
RL IS MQL+++P D C KFGS + + E+ +V
Sbjct: 164 TMRLTISAECPMQLEDFPMDAHACPLKFGSYAYPNSEVVYV 204
>BT009830-1|AAP88832.1| 462|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 5 protein.
Length = 462
Score = 54.0 bits (124), Expect = 6e-07
Identities = 39/161 (24%), Positives = 73/161 (45%), Gaps = 7/161 (4%)
Frame = +3
Query: 90 ENATSLSLMIDSLLATYDRESPPD--SKIV-VNLTLHLRHAN-IRESESTVRILADLQMN 257
+N T + ++D LL YD P +I V +++ + ++E I + +
Sbjct: 44 DNITIFTRILDGLLDGYDNRLRPGLGERITQVRTDIYVTSFGPVSDTEMEYTIDVFFRQS 103
Query: 258 WIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSW 428
W D+RL + + + ++W PD N + A + R+ ++G++ +
Sbjct: 104 WKDERLRFKGPMQRLPLNNLLASKIWTPDTFFHNGKKSIAHNMTTPNKLLRLEDDGTLLY 163
Query: 429 IKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFV 551
RL IS MQL+++P D C KFGS + + E+ +V
Sbjct: 164 TMRLTISAECPMQLEDFPMDAHACPLKFGSYAYPNSEVVYV 204
>BC113422-1|AAI13423.1| 462|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 5 protein.
Length = 462
Score = 54.0 bits (124), Expect = 6e-07
Identities = 39/161 (24%), Positives = 73/161 (45%), Gaps = 7/161 (4%)
Frame = +3
Query: 90 ENATSLSLMIDSLLATYDRESPPD--SKIV-VNLTLHLRHAN-IRESESTVRILADLQMN 257
+N T + ++D LL YD P +I V +++ + ++E I + +
Sbjct: 44 DNITIFTRILDGLLDGYDNRLRPGLGERITQVRTDIYVTSFGPVSDTEMEYTIDVFFRQS 103
Query: 258 WIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSW 428
W D+RL + + + ++W PD N + A + R+ ++G++ +
Sbjct: 104 WKDERLRFKGPMQRLPLNNLLASKIWTPDTFFHNGKKSIAHNMTTPNKLLRLEDDGTLLY 163
Query: 429 IKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFV 551
RL IS MQL+++P D C KFGS + + E+ +V
Sbjct: 164 TMRLTISAECPMQLEDFPMDAHACPLKFGSYAYPNSEVVYV 204
>BC111979-1|AAI11980.1| 462|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 5, precursor protein.
Length = 462
Score = 54.0 bits (124), Expect = 6e-07
Identities = 39/161 (24%), Positives = 73/161 (45%), Gaps = 7/161 (4%)
Frame = +3
Query: 90 ENATSLSLMIDSLLATYDRESPPD--SKIV-VNLTLHLRHAN-IRESESTVRILADLQMN 257
+N T + ++D LL YD P +I V +++ + ++E I + +
Sbjct: 44 DNITIFTRILDGLLDGYDNRLRPGLGERITQVRTDIYVTSFGPVSDTEMEYTIDVFFRQS 103
Query: 258 WIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSW 428
W D+RL + + + ++W PD N + A + R+ ++G++ +
Sbjct: 104 WKDERLRFKGPMQRLPLNNLLASKIWTPDTFFHNGKKSIAHNMTTPNKLLRLEDDGTLLY 163
Query: 429 IKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFV 551
RL IS MQL+++P D C KFGS + + E+ +V
Sbjct: 164 TMRLTISAECPMQLEDFPMDAHACPLKFGSYAYPNSEVVYV 204
>AB223030-1|BAE19924.1| 411|Homo sapiens ligand-gated ion-channel
receptor L2 protein.
Length = 411
Score = 54.0 bits (124), Expect = 6e-07
Identities = 28/101 (27%), Positives = 49/101 (48%)
Frame = +3
Query: 246 LQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVS 425
L+++W+D RL+WN + E LW P + +L A D + +ARV +G V
Sbjct: 86 LRLSWLDTRLAWNTSAHPRHAITLPWESLWTPRLTILEALWVDWRDQSPQARVDQDGHVK 145
Query: 426 WIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDF 548
L T + +L ++P D C+ F + + + E++F
Sbjct: 146 LNLALATETNCNFELLHFPRDHSNCSLSFYALSNTAMELEF 186
>M59216-1|AAA35862.1| 474|Homo sapiens gamma-aminobutyric acid
receptor beta-1 subunit protein.
Length = 474
Score = 53.6 bits (123), Expect = 9e-07
Identities = 40/171 (23%), Positives = 74/171 (43%), Gaps = 7/171 (4%)
Frame = +3
Query: 57 LTCAIASAAECENATSLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESES 224
+ C S E N + + +D LL YD PD + V + + + + + E
Sbjct: 21 MVCCAHSTNEPSNMSYVKETVDRLLKGYDIRLRPDFGGPPVDVGMRIDVASIDMVSEVNM 80
Query: 225 TVRILADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR--- 395
+ Q +W DKRLS++ + +++LW PD LN + ++
Sbjct: 81 DYTLTMYFQQSWKDKRLSYSGIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRM 140
Query: 396 ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDF 548
R+ +G+V + R+ + M L +P D Q CT + S + +D+++F
Sbjct: 141 IRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEF 191
>X14767-1|CAA32875.1| 474|Homo sapiens GABA-A receptor beta 1
subunit protein.
Length = 474
Score = 52.8 bits (121), Expect = 1e-06
Identities = 40/171 (23%), Positives = 73/171 (42%), Gaps = 7/171 (4%)
Frame = +3
Query: 57 LTCAIASAAECENATSLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESES 224
+ C S E N + +D LL YD PD + V + + + + + E
Sbjct: 21 MVCCAHSTNEPSNMPYVKETVDRLLKGYDIRLRPDFGGPPVDVGMRIDVASIDMVSEVNM 80
Query: 225 TVRILADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR--- 395
+ Q +W DKRLS++ + +++LW PD LN + ++
Sbjct: 81 DYTLTMYFQQSWKDKRLSYSGIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRM 140
Query: 396 ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDF 548
R+ +G+V + R+ + M L +P D Q CT + S + +D+++F
Sbjct: 141 IRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEF 191
>BC111802-1|AAI11803.1| 465|Homo sapiens CHRNG protein protein.
Length = 465
Score = 51.2 bits (117), Expect = 5e-06
Identities = 40/133 (30%), Positives = 62/133 (46%), Gaps = 7/133 (5%)
Frame = +3
Query: 54 LLTCAIASAAECENATSLSLMIDSLLATYDRESPPDSKI--VVNLTLHLRHANI---RES 218
LL A+ A+ N L+ D L+ YD P + VVN++L L N+ E
Sbjct: 11 LLLLAVCLGAQGRNQEE-RLLAD-LMQNYDPNLRPAERDSDVVNVSLKLTLTNLISLNER 68
Query: 219 ESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAAT-TAGDYAL 392
E + ++M W D RL W+ ++ G V S +WRPD+VL N + T + + L
Sbjct: 69 EEALTTNVWIEMQWCDYRLRWDPRDYEGLWVLRVPSTMVWRPDIVLENKSQTYSTNEIDL 128
Query: 393 RARVSNNGSVSWI 431
+ + S+ WI
Sbjct: 129 QLSQEDGQSIEWI 141
>BC028629-1|AAH28629.1| 492|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 3 protein.
Length = 492
Score = 51.2 bits (117), Expect = 5e-06
Identities = 36/158 (22%), Positives = 70/158 (44%), Gaps = 7/158 (4%)
Frame = +3
Query: 90 ENATSLSLMIDSLLATYDRESPP---DSKIVVNLTLHLRHAN-IRESESTVRILADLQMN 257
+N T + ++D LL YD P D+ V +++ + +++ I +
Sbjct: 62 DNITIFTRILDRLLDGYDNRLRPGLGDAVTEVKTDIYVTSFGPVSDTDMEYTIDVFFRQT 121
Query: 258 WIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSW 428
W D+RL ++ + + ++W PD N + A + R+ +NG++ +
Sbjct: 122 WHDERLKFDGPMKILPLNNLLASKIWTPDTFFHNGKKSVAHNMTTPNKLLRLVDNGTLPY 181
Query: 429 IKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEM 542
RL I M L+++P D+ C KFGS + + E+
Sbjct: 182 TMRLTIHAECPMHLEDFPMDVHACPLKFGSYAYTTAEV 219
>S82769-1|AAB39369.1| 467|Homo sapiens GABAA receptor gamma 3
subunit protein.
Length = 467
Score = 50.8 bits (116), Expect = 6e-06
Identities = 39/172 (22%), Positives = 73/172 (42%), Gaps = 7/172 (4%)
Frame = +3
Query: 99 TSLSLMIDSLLATYDRESPPDSKI---VVNLTLHLRHAN-IRESESTVRILADLQMNWID 266
T ++L+++ LL YD++ PD I V+++ +++ + +I W D
Sbjct: 45 TDVTLILNKLLREYDKKLRPDIGIKPTVIDVDIYVNSIGPVSSINMEYQIDIFFAQTWTD 104
Query: 267 KRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKR 437
RL +N+ + +W PD + N+ A R+ N+G + + R
Sbjct: 105 SRLRFNSTMKILTLNSNMVGLIWIPDTIFRNSKTAEAHWITTPNQLLRIWNDGKILYTLR 164
Query: 438 LDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDKRIYSMFESGAW 593
L I+ +QL N+P D +C F S + +EM + K + +W
Sbjct: 165 LTINAECQLQLHNFPMDEHSCPLIFSSYGYPKEEMIYRWRKNSVEAADQKSW 216
>S62908-1|AAB27279.1| 492|Homo sapiens gamma-aminobutyric acidA
receptor alpha 3 subunit protein.
Length = 492
Score = 50.8 bits (116), Expect = 6e-06
Identities = 36/158 (22%), Positives = 70/158 (44%), Gaps = 7/158 (4%)
Frame = +3
Query: 90 ENATSLSLMIDSLLATYDRESPP---DSKIVVNLTLHLRHAN-IRESESTVRILADLQMN 257
+N T + ++D LL YD P D+ V +++ + +++ I +
Sbjct: 62 DNITIFTRILDRLLDGYDNRLRPGLGDAVTEVKTDIYVTSFGPVSDTDMEYTIDVFFRQT 121
Query: 258 WIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSW 428
W D+RL ++ + + ++W PD N + A + R+ +NG++ +
Sbjct: 122 WHDERLKFDGPMKILPLNNLLASKIWTPDTFFHNGKKSVAHNMTTPNKLLRLVDNGTLLY 181
Query: 429 IKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEM 542
RL I M L+++P D+ C KFGS + + E+
Sbjct: 182 TMRLTIHAECPMHLEDFPMDVHACPLKFGSYAYTTAEV 219
>AK122638-1|BAC85499.1| 266|Homo sapiens yte protein of 76kDa)
(LCP2). protein.
Length = 266
Score = 50.8 bits (116), Expect = 6e-06
Identities = 26/89 (29%), Positives = 42/89 (47%)
Frame = +3
Query: 246 LQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVS 425
L+++W+D RL+WN + E LW P + +L A D + +ARV +G V
Sbjct: 87 LRLSWLDTRLAWNTSAHPRHAITLPWESLWTPRLTILEALWVDWRDQSPQARVDQDGHVK 146
Query: 426 WIKRLDISTPISMQLDNWPNDMQTCTFKF 512
L T + +L ++P D C+ F
Sbjct: 147 LNLALTTETNCNFELLHFPRDHSNCSLSF 175
>AF269144-1|AAF99698.1| 467|Homo sapiens GABAA receptor gamma 3
subunit protein.
Length = 467
Score = 50.8 bits (116), Expect = 6e-06
Identities = 39/172 (22%), Positives = 73/172 (42%), Gaps = 7/172 (4%)
Frame = +3
Query: 99 TSLSLMIDSLLATYDRESPPDSKI---VVNLTLHLRHAN-IRESESTVRILADLQMNWID 266
T ++L+++ LL YD++ PD I V+++ +++ + +I W D
Sbjct: 45 TDVTLILNKLLREYDKKLRPDIGIKPTVIDVDIYVNSIGPVSSINMEYQIDIFFAQTWTD 104
Query: 267 KRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKR 437
RL +N+ + +W PD + N+ A R+ N+G + + R
Sbjct: 105 SRLRFNSTMKILTLNSNMVGLIWIPDTIFRNSKTAEAHWITTPNQLLRIWNDGKILYTLR 164
Query: 438 LDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDKRIYSMFESGAW 593
L I+ +QL N+P D +C F S + +EM + K + +W
Sbjct: 165 LTINAECQLQLHNFPMDEHSCPLIFSSYGYPKEEMIYRWRKNSVEAADQKSW 216
>AF228458-1|AAF63215.1| 449|Homo sapiens GABAA receptor gamma 3
subunit protein.
Length = 449
Score = 50.8 bits (116), Expect = 6e-06
Identities = 39/172 (22%), Positives = 73/172 (42%), Gaps = 7/172 (4%)
Frame = +3
Query: 99 TSLSLMIDSLLATYDRESPPDSKI---VVNLTLHLRHAN-IRESESTVRILADLQMNWID 266
T ++L+++ LL YD++ PD I V+++ +++ + +I W D
Sbjct: 27 TDVTLILNKLLREYDKKLRPDIGIKPTVIDVDIYVNSIGPVSSINMEYQIDIFFAQTWTD 86
Query: 267 KRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKR 437
RL +N+ + +W PD + N+ A R+ N+G + + R
Sbjct: 87 SRLRFNSTMKILTLNSNMVGLIWIPDTIFRNSKTAEAHWITTPNQLLRIWNDGKILYTLR 146
Query: 438 LDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDKRIYSMFESGAW 593
L I+ +QL N+P D +C F S + +EM + K + +W
Sbjct: 147 LTINAECQLQLHNFPMDEHSCPLIFSSYGYPKEEMIYRWRKNSVEAADQKSW 198
>AF166361-1|AAG12455.1| 492|Homo sapiens GABA receptor subunit
alpha 3 protein.
Length = 492
Score = 50.8 bits (116), Expect = 6e-06
Identities = 36/158 (22%), Positives = 70/158 (44%), Gaps = 7/158 (4%)
Frame = +3
Query: 90 ENATSLSLMIDSLLATYDRESPP---DSKIVVNLTLHLRHAN-IRESESTVRILADLQMN 257
+N T + ++D LL YD P D+ V +++ + +++ I +
Sbjct: 62 DNITIFTRILDRLLDGYDNRLRPGLGDAVTEVKTDIYVTSFGPVSDTDMEYTIDVFFRQT 121
Query: 258 WIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSW 428
W D+RL ++ + + ++W PD N + A + R+ +NG++ +
Sbjct: 122 WHDERLKFDGPMKILPLNNLLASKIWTPDTFFHNGKKSVAHNMTTPNKLLRLVDNGTLLY 181
Query: 429 IKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEM 542
RL I M L+++P D+ C KFGS + + E+
Sbjct: 182 TMRLTIHAECPMHLEDFPMDVHACPLKFGSYAYTTAEV 219
>U77731-2|AAB38273.1| 360|Homo sapiens glycine receptor alpha 2B
subunit protein.
Length = 360
Score = 50.0 bits (114), Expect = 1e-05
Identities = 39/145 (26%), Positives = 65/145 (44%), Gaps = 8/145 (5%)
Frame = +3
Query: 138 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 305
YD P+ K VN+T ++ +I E+ R+ L+ W D RL+++
Sbjct: 58 YDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDSRLAYSEYPDDSL 117
Query: 306 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLD 473
S + +W+PD+ N D R+S NG V + RL ++ M L
Sbjct: 118 DLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLK 177
Query: 474 NWPNDMQTCTFKFGSRMHNSDEMDF 548
N+P D+QTCT + S + +++ F
Sbjct: 178 NFPMDVQTCTMQLESFGYTMNDLIF 202
>CR450343-1|CAG29339.1| 452|Homo sapiens GLRA2 protein.
Length = 452
Score = 50.0 bits (114), Expect = 1e-05
Identities = 39/145 (26%), Positives = 65/145 (44%), Gaps = 8/145 (5%)
Frame = +3
Query: 138 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 305
YD P+ K VN+T ++ +I E+ R+ L+ W D RL+++
Sbjct: 58 YDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDSRLAYSEYPDDSL 117
Query: 306 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLD 473
S + +W+PD+ N D R+S NG V + RL ++ M L
Sbjct: 118 DLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLK 177
Query: 474 NWPNDMQTCTFKFGSRMHNSDEMDF 548
N+P D+QTCT + S + +++ F
Sbjct: 178 NFPMDVQTCTMQLESFGYTMNDLIF 202
>AY437084-1|AAR87843.1| 452|Homo sapiens glycine receptor alpha2
subunit B protein.
Length = 452
Score = 50.0 bits (114), Expect = 1e-05
Identities = 39/145 (26%), Positives = 65/145 (44%), Gaps = 8/145 (5%)
Frame = +3
Query: 138 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 305
YD P+ K VN+T ++ +I E+ R+ L+ W D RL+++
Sbjct: 58 YDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDSRLAYSEYPDDSL 117
Query: 306 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLD 473
S + +W+PD+ N D R+S NG V + RL ++ M L
Sbjct: 118 DLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLK 177
Query: 474 NWPNDMQTCTFKFGSRMHNSDEMDF 548
N+P D+QTCT + S + +++ F
Sbjct: 178 NFPMDVQTCTMQLESFGYTMNDLIF 202
>AJ003080-1|CAA05853.1| 238|Homo sapiens serotonin receptor
protein.
Length = 238
Score = 50.0 bits (114), Expect = 1e-05
Identities = 27/111 (24%), Positives = 49/111 (44%), Gaps = 1/111 (0%)
Frame = +3
Query: 204 NIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAG 380
N+ E + + W D+ L WN ++ T L + ++ +W PD+++
Sbjct: 72 NVDEKNQVLTTYIWYRQYWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKS 131
Query: 381 DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNS 533
+ + G V K L + T S+ + N+P D+Q C+ F S +H S
Sbjct: 132 PNIPYVYIRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLHTS 182
>X52008-1|CAA36257.1| 452|Homo sapiens inhibitory glycine receptor
protein.
Length = 452
Score = 49.6 bits (113), Expect = 1e-05
Identities = 38/145 (26%), Positives = 65/145 (44%), Gaps = 8/145 (5%)
Frame = +3
Query: 138 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 305
YD P+ K VN+T ++ ++ E+ R+ L+ W D RL+++
Sbjct: 58 YDARIRPNFKGPPVNVTCNIFINSFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPDDSL 117
Query: 306 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLD 473
S + +W+PD+ N D R+S NG V + RL ++ M L
Sbjct: 118 DLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLK 177
Query: 474 NWPNDMQTCTFKFGSRMHNSDEMDF 548
N+P D+QTCT + S + +++ F
Sbjct: 178 NFPMDVQTCTMQLESFGYTMNDLIF 202
>U77731-1|AAB38272.1| 360|Homo sapiens glycine receptor alpha 2
subunit protein.
Length = 360
Score = 49.6 bits (113), Expect = 1e-05
Identities = 38/145 (26%), Positives = 65/145 (44%), Gaps = 8/145 (5%)
Frame = +3
Query: 138 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 305
YD P+ K VN+T ++ ++ E+ R+ L+ W D RL+++
Sbjct: 58 YDARIRPNFKGPPVNVTCNIFINSFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPDDSL 117
Query: 306 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLD 473
S + +W+PD+ N D R+S NG V + RL ++ M L
Sbjct: 118 DLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLK 177
Query: 474 NWPNDMQTCTFKFGSRMHNSDEMDF 548
N+P D+QTCT + S + +++ F
Sbjct: 178 NFPMDVQTCTMQLESFGYTMNDLIF 202
>S82612-1|AAB37533.2| 478|Homo sapiens 5-hydroxytryptamine type 3AS
receptor subunit protein.
Length = 478
Score = 49.6 bits (113), Expect = 1e-05
Identities = 26/115 (22%), Positives = 51/115 (44%), Gaps = 1/115 (0%)
Frame = +3
Query: 204 NIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAG 380
N+ E + + W D+ L WN ++ T L + ++ +W PD+++
Sbjct: 72 NVDEKNQVLTTYIWYRQYWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINELVDVGKS 131
Query: 381 DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 545
+ + G V K L + T S+ + N+P D+Q C+ F S +H +++
Sbjct: 132 PNIPYVYIRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLHTIQDIN 186
>BC032864-1|AAH32864.1| 452|Homo sapiens glycine receptor, alpha 2
protein.
Length = 452
Score = 49.6 bits (113), Expect = 1e-05
Identities = 38/145 (26%), Positives = 65/145 (44%), Gaps = 8/145 (5%)
Frame = +3
Query: 138 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 305
YD P+ K VN+T ++ ++ E+ R+ L+ W D RL+++
Sbjct: 58 YDARIRPNFKGPPVNVTCNIFINSFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPDDSL 117
Query: 306 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLD 473
S + +W+PD+ N D R+S NG V + RL ++ M L
Sbjct: 118 DLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLK 177
Query: 474 NWPNDMQTCTFKFGSRMHNSDEMDF 548
N+P D+QTCT + S + +++ F
Sbjct: 178 NFPMDVQTCTMQLESFGYTMNDLIF 202
>AY437083-1|AAR87842.1| 452|Homo sapiens glycine receptor alpha2
subunit A protein.
Length = 452
Score = 49.6 bits (113), Expect = 1e-05
Identities = 38/145 (26%), Positives = 65/145 (44%), Gaps = 8/145 (5%)
Frame = +3
Query: 138 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 305
YD P+ K VN+T ++ ++ E+ R+ L+ W D RL+++
Sbjct: 58 YDARIRPNFKGPPVNVTCNIFINSFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPDDSL 117
Query: 306 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLD 473
S + +W+PD+ N D R+S NG V + RL ++ M L
Sbjct: 118 DLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLK 177
Query: 474 NWPNDMQTCTFKFGSRMHNSDEMDF 548
N+P D+QTCT + S + +++ F
Sbjct: 178 NFPMDVQTCTMQLESFGYTMNDLIF 202
>AF053495-1|AAC35290.1| 452|Homo sapiens glycine receptor alpha 2
subunit protein.
Length = 452
Score = 49.6 bits (113), Expect = 1e-05
Identities = 38/145 (26%), Positives = 65/145 (44%), Gaps = 8/145 (5%)
Frame = +3
Query: 138 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 305
YD P+ K VN+T ++ ++ E+ R+ L+ W D RL+++
Sbjct: 58 YDARIRPNFKGPPVNVTCNIFINSFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPDDSL 117
Query: 306 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLD 473
S + +W+PD+ N D R+S NG V + RL ++ M L
Sbjct: 118 DLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLK 177
Query: 474 NWPNDMQTCTFKFGSRMHNSDEMDF 548
N+P D+QTCT + S + +++ F
Sbjct: 178 NFPMDVQTCTMQLESFGYTMNDLIF 202
>S81944-1|AAB36480.1| 453|Homo sapiens gamma-aminobutyric acid type
A receptor alpha 6 subunit protein.
Length = 453
Score = 49.2 bits (112), Expect = 2e-05
Identities = 39/166 (23%), Positives = 71/166 (42%), Gaps = 8/166 (4%)
Frame = +3
Query: 102 SLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESESTVRILADLQMNWIDK 269
++S ++D+LL YD P + V +++ + + E + + W D+
Sbjct: 31 NVSRILDNLLEGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTDE 90
Query: 270 RLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRA---RVSNNGSVSWIKRL 440
RL + S + ++W PD N + A + R+ NG++ + RL
Sbjct: 91 RLKFGGPTEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTMRL 150
Query: 441 DISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDK-RIYSM 575
I+ M+L N+P D C KFGS + E+ + K +YS+
Sbjct: 151 TINADCPMRLVNFPMDGHACPLKFGSYAYPKSEIIYTWKKGPLYSV 196
>D49394-1|BAA08387.1| 478|Homo sapiens serotonin 5-HT3 receptor
protein.
Length = 478
Score = 49.2 bits (112), Expect = 2e-05
Identities = 26/115 (22%), Positives = 51/115 (44%), Gaps = 1/115 (0%)
Frame = +3
Query: 204 NIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAG 380
N+ E + + W D+ L WN ++ T L + ++ +W PD+++
Sbjct: 72 NVDEKNQVLTTYIWYRQYWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKS 131
Query: 381 DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 545
+ + G V K L + T S+ + N+P D+Q C+ F S +H +++
Sbjct: 132 PNIPYVYIRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLHTIQDIN 186
>BT007204-1|AAP35868.1| 484|Homo sapiens 5-hydroxytryptamine
(serotonin) receptor 3A protein.
Length = 484
Score = 49.2 bits (112), Expect = 2e-05
Identities = 26/115 (22%), Positives = 51/115 (44%), Gaps = 1/115 (0%)
Frame = +3
Query: 204 NIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAG 380
N+ E + + W D+ L WN ++ T L + ++ +W PD+++
Sbjct: 78 NVDEKNQVLTTYIWYRQYWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKS 137
Query: 381 DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 545
+ + G V K L + T S+ + N+P D+Q C+ F S +H +++
Sbjct: 138 PNIPYVYIRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLHTIQDIN 192
>BC099641-1|AAH99641.1| 453|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 6 protein.
Length = 453
Score = 49.2 bits (112), Expect = 2e-05
Identities = 39/166 (23%), Positives = 71/166 (42%), Gaps = 8/166 (4%)
Frame = +3
Query: 102 SLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESESTVRILADLQMNWIDK 269
++S ++D+LL YD P + V +++ + + E + + W D+
Sbjct: 31 NVSRILDNLLEGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTDE 90
Query: 270 RLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRA---RVSNNGSVSWIKRL 440
RL + S + ++W PD N + A + R+ NG++ + RL
Sbjct: 91 RLKFGGPTEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTMRL 150
Query: 441 DISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDK-RIYSM 575
I+ M+L N+P D C KFGS + E+ + K +YS+
Sbjct: 151 TINADCPMRLVNFPMDGHACPLKFGSYAYPKSEIIYTWKKGPLYSV 196
>BC099640-1|AAH99640.1| 453|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 6 protein.
Length = 453
Score = 49.2 bits (112), Expect = 2e-05
Identities = 39/166 (23%), Positives = 71/166 (42%), Gaps = 8/166 (4%)
Frame = +3
Query: 102 SLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESESTVRILADLQMNWIDK 269
++S ++D+LL YD P + V +++ + + E + + W D+
Sbjct: 31 NVSRILDNLLEGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTDE 90
Query: 270 RLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRA---RVSNNGSVSWIKRL 440
RL + S + ++W PD N + A + R+ NG++ + RL
Sbjct: 91 RLKFGGPTEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTMRL 150
Query: 441 DISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDK-RIYSM 575
I+ M+L N+P D C KFGS + E+ + K +YS+
Sbjct: 151 TINADCPMRLVNFPMDGHACPLKFGSYAYPKSEIIYTWKKGPLYSV 196
>BC096242-1|AAH96242.1| 453|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 6 protein.
Length = 453
Score = 49.2 bits (112), Expect = 2e-05
Identities = 39/166 (23%), Positives = 71/166 (42%), Gaps = 8/166 (4%)
Frame = +3
Query: 102 SLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESESTVRILADLQMNWIDK 269
++S ++D+LL YD P + V +++ + + E + + W D+
Sbjct: 31 NVSRILDNLLEGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTDE 90
Query: 270 RLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRA---RVSNNGSVSWIKRL 440
RL + S + ++W PD N + A + R+ NG++ + RL
Sbjct: 91 RLKFGGPTEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTMRL 150
Query: 441 DISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDK-RIYSM 575
I+ M+L N+P D C KFGS + E+ + K +YS+
Sbjct: 151 TINADCPMRLVNFPMDGHACPLKFGSYAYPKSEIIYTWKKGPLYSV 196
>BC096241-1|AAH96241.1| 453|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 6 protein.
Length = 453
Score = 49.2 bits (112), Expect = 2e-05
Identities = 39/166 (23%), Positives = 71/166 (42%), Gaps = 8/166 (4%)
Frame = +3
Query: 102 SLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESESTVRILADLQMNWIDK 269
++S ++D+LL YD P + V +++ + + E + + W D+
Sbjct: 31 NVSRILDNLLEGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTDE 90
Query: 270 RLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRA---RVSNNGSVSWIKRL 440
RL + S + ++W PD N + A + R+ NG++ + RL
Sbjct: 91 RLKFGGPTEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTMRL 150
Query: 441 DISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDK-RIYSM 575
I+ M+L N+P D C KFGS + E+ + K +YS+
Sbjct: 151 TINADCPMRLVNFPMDGHACPLKFGSYAYPKSEIIYTWKKGPLYSV 196
>BC004453-1|AAH04453.2| 478|Homo sapiens 5-hydroxytryptamine
(serotonin) receptor 3A protein.
Length = 478
Score = 49.2 bits (112), Expect = 2e-05
Identities = 26/115 (22%), Positives = 51/115 (44%), Gaps = 1/115 (0%)
Frame = +3
Query: 204 NIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAG 380
N+ E + + W D+ L WN ++ T L + ++ +W PD+++
Sbjct: 72 NVDEKNQVLTTYIWYRQYWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKS 131
Query: 381 DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 545
+ + G V K L + T S+ + N+P D+Q C+ F S +H +++
Sbjct: 132 PNIPYVYIRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLHTIQDIN 186
>BC002354-1|AAH02354.1| 478|Homo sapiens 5-hydroxytryptamine
(serotonin) receptor 3A protein.
Length = 478
Score = 49.2 bits (112), Expect = 2e-05
Identities = 26/115 (22%), Positives = 51/115 (44%), Gaps = 1/115 (0%)
Frame = +3
Query: 204 NIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAG 380
N+ E + + W D+ L WN ++ T L + ++ +W PD+++
Sbjct: 72 NVDEKNQVLTTYIWYRQYWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKS 131
Query: 381 DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 545
+ + G V K L + T S+ + N+P D+Q C+ F S +H +++
Sbjct: 132 PNIPYVYIRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLHTIQDIN 186
>AJ005205-1|CAA06442.3| 478|Homo sapiens serotonin 3 receptor
protein.
Length = 478
Score = 49.2 bits (112), Expect = 2e-05
Identities = 26/115 (22%), Positives = 51/115 (44%), Gaps = 1/115 (0%)
Frame = +3
Query: 204 NIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAG 380
N+ E + + W D+ L WN ++ T L + ++ +W PD+++
Sbjct: 72 NVDEKNQVLTTYIWYRQYWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKS 131
Query: 381 DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 545
+ + G V K L + T S+ + N+P D+Q C+ F S +H +++
Sbjct: 132 PNIPYVYIRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLHTIQDIN 186
>AJ003079-1|CAA05852.1| 478|Homo sapiens 5-hydroxytryptamine3
receptor protein.
Length = 478
Score = 49.2 bits (112), Expect = 2e-05
Identities = 26/115 (22%), Positives = 51/115 (44%), Gaps = 1/115 (0%)
Frame = +3
Query: 204 NIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAG 380
N+ E + + W D+ L WN ++ T L + ++ +W PD+++
Sbjct: 72 NVDEKNQVLTTYIWYRQYWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKS 131
Query: 381 DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 545
+ + G V K L + T S+ + N+P D+Q C+ F S +H +++
Sbjct: 132 PNIPYVYIRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLHTIQDIN 186
>AJ003078-1|CAA05851.1| 510|Homo sapiens serotonin receptor
protein.
Length = 510
Score = 49.2 bits (112), Expect = 2e-05
Identities = 26/115 (22%), Positives = 51/115 (44%), Gaps = 1/115 (0%)
Frame = +3
Query: 204 NIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAG 380
N+ E + + W D+ L WN ++ T L + ++ +W PD+++
Sbjct: 72 NVDEKNQVLTTYIWYRQYWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKS 131
Query: 381 DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 545
+ + G V K L + T S+ + N+P D+Q C+ F S +H +++
Sbjct: 132 PNIPYVYIRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLHTIQDIN 186
>AF498984-1|AAM21131.1| 478|Homo sapiens 5-hydroxytryptamine
receptor 3A protein.
Length = 478
Score = 49.2 bits (112), Expect = 2e-05
Identities = 26/115 (22%), Positives = 51/115 (44%), Gaps = 1/115 (0%)
Frame = +3
Query: 204 NIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAG 380
N+ E + + W D+ L WN ++ T L + ++ +W PD+++
Sbjct: 72 NVDEKNQVLTTYIWYRQYWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKS 131
Query: 381 DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 545
+ + G V K L + T S+ + N+P D+Q C+ F S +H +++
Sbjct: 132 PNIPYVYIRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLHTIQDIN 186
>U30461-1|AAB52519.1| 554|Homo sapiens GABAA receptor subunit
alpha4 protein.
Length = 554
Score = 48.4 bits (110), Expect = 3e-05
Identities = 32/119 (26%), Positives = 52/119 (43%), Gaps = 3/119 (2%)
Frame = +3
Query: 213 ESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYAL 392
E E T+ + + WIDKRL ++ + ++W PD N + + +
Sbjct: 90 EMEYTMDVF--FRQTWIDKRLKYDGPIEILRLNNMMVTKVWTPDTFFRNGKKSVSHNMTA 147
Query: 393 RA---RVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDK 560
R+ NG++ + RL IS M+L ++P D C KFGS + EM + K
Sbjct: 148 PNKLFRIMRNGTILYTMRLTISAECPMRLVDFPMDGHACPLKFGSYAYPKSEMIYTWTK 206
>BC035055-1|AAH35055.1| 554|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 4 protein.
Length = 554
Score = 48.4 bits (110), Expect = 3e-05
Identities = 32/119 (26%), Positives = 52/119 (43%), Gaps = 3/119 (2%)
Frame = +3
Query: 213 ESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYAL 392
E E T+ + + WIDKRL ++ + ++W PD N + + +
Sbjct: 90 EMEYTMDVF--FRQTWIDKRLKYDGPIEILRLNNMMVTKVWTPDTFFRNGKKSVSHNMTA 147
Query: 393 RA---RVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDK 560
R+ NG++ + RL IS M+L ++P D C KFGS + EM + K
Sbjct: 148 PNKLFRIMRNGTILYTMRLTISAECPMRLVDFPMDGHACPLKFGSYAYPKSEMIYTWTK 206
>BC022449-1|AAH22449.1| 474|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, beta 1 protein.
Length = 474
Score = 48.4 bits (110), Expect = 3e-05
Identities = 39/171 (22%), Positives = 73/171 (42%), Gaps = 7/171 (4%)
Frame = +3
Query: 57 LTCAIASAAECENATSLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESES 224
+ C S E N + + +D LL YD PD + V + + + + + E
Sbjct: 21 MVCCAHSTNEPSNMSYVKETVDRLLKGYDIRLRPDFGGPPVDVGMRIDVASIDMVSEVNM 80
Query: 225 TVRILADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR--- 395
+ Q +W DKRLS++ + +++L PD LN + ++
Sbjct: 81 DYTLTMYFQQSWKDKRLSYSGIPLNLTLDNRVADQLCVPDTYFLNDKKSFVHGVTVKNRM 140
Query: 396 ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDF 548
R+ +G+V + R+ + M L +P D Q CT + S + +D+++F
Sbjct: 141 IRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEF 191
>U95367-1|AAC51357.1| 440|Homo sapiens GABA-A receptor pi subunit
protein.
Length = 440
Score = 46.8 bits (106), Expect = 1e-04
Identities = 40/164 (24%), Positives = 78/164 (47%), Gaps = 9/164 (5%)
Frame = +3
Query: 84 ECENATSLSLM-IDSLLATYDRESPPD---SKIVVNLTLHLRH-ANIRESESTVRILADL 248
E + LSL ++L A Y++ P+ + + LTL + ++I ES L
Sbjct: 29 EVGRSDKLSLPGFENLTAGYNKFLRPNFGGEPVQIALTLDIASISSISESNMDYTATIYL 88
Query: 249 QMNWIDKRLSWNAGE-WGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNG 416
+ W+D+RL + + + LV E LW PD ++ + + + + R+ +NG
Sbjct: 89 RQRWMDQRLVFEGNKSFTLDARLV--EFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNG 146
Query: 417 SVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDF 548
+V + R+ + +M L +P D QTC + S ++ ++++F
Sbjct: 147 TVLYALRITTTVACNMDLSKYPMDTQTCKLQLESWGYDGNDVEF 190
>BC109211-1|AAI09212.1| 632|Homo sapiens gamma-aminobutyric acid
(GABA) receptor, theta protein.
Length = 632
Score = 46.8 bits (106), Expect = 1e-04
Identities = 35/145 (24%), Positives = 60/145 (41%), Gaps = 7/145 (4%)
Frame = +3
Query: 87 CENATSLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESESTVRILADLQM 254
C N + ++D +L+ YD P+ + + V +++++ I E I
Sbjct: 53 CANEAVVQKILDRVLSRYDVRLRPNFGGAPVPVRISIYVTSIEQISEMNMDYTITMFFHQ 112
Query: 255 NWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSN---NGSVS 425
W D RL++ + E+LW PD LN+ D + RV +G+V
Sbjct: 113 TWKDSRLAYYETTLNLTLDYRMHEKLWVPDCYFLNSKDAFVHDVTVENRVFQLHPDGTVR 172
Query: 426 WIKRLDISTPISMQLDNWPNDMQTC 500
+ RL + S+ L +P D Q C
Sbjct: 173 YGIRLTTTAACSLDLHKFPMDKQAC 197
>BC109210-1|AAI09211.1| 632|Homo sapiens gamma-aminobutyric acid
(GABA) receptor, theta protein.
Length = 632
Score = 46.8 bits (106), Expect = 1e-04
Identities = 35/145 (24%), Positives = 60/145 (41%), Gaps = 7/145 (4%)
Frame = +3
Query: 87 CENATSLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESESTVRILADLQM 254
C N + ++D +L+ YD P+ + + V +++++ I E I
Sbjct: 53 CANEAVVQKILDRVLSRYDVRLRPNFGGAPVPVRISIYVTSIEQISEMNMDYTITMFFHQ 112
Query: 255 NWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSN---NGSVS 425
W D RL++ + E+LW PD LN+ D + RV +G+V
Sbjct: 113 TWKDSRLAYYETTLNLTLDYRMHEKLWVPDCYFLNSKDAFVHDVTVENRVFQLHPDGTVR 172
Query: 426 WIKRLDISTPISMQLDNWPNDMQTC 500
+ RL + S+ L +P D Q C
Sbjct: 173 YGIRLTTTAACSLDLHKFPMDKQAC 197
>BC109106-1|AAI09107.1| 440|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, pi protein.
Length = 440
Score = 46.8 bits (106), Expect = 1e-04
Identities = 40/164 (24%), Positives = 78/164 (47%), Gaps = 9/164 (5%)
Frame = +3
Query: 84 ECENATSLSLM-IDSLLATYDRESPPD---SKIVVNLTLHLRH-ANIRESESTVRILADL 248
E + LSL ++L A Y++ P+ + + LTL + ++I ES L
Sbjct: 29 EVGRSDKLSLPGFENLTAGYNKFLRPNFGGEPVQIALTLDIASISSISESNMDYTATIYL 88
Query: 249 QMNWIDKRLSWNAGE-WGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNG 416
+ W+D+RL + + + LV E LW PD ++ + + + + R+ +NG
Sbjct: 89 RQRWMDQRLVFEGNKSFTLDARLV--EFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNG 146
Query: 417 SVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDF 548
+V + R+ + +M L +P D QTC + S ++ ++++F
Sbjct: 147 TVLYALRITTTVACNMDLSKYPMDTQTCKLQLESWGYDGNDVEF 190
>BC109105-1|AAI09106.1| 440|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, pi protein.
Length = 440
Score = 46.8 bits (106), Expect = 1e-04
Identities = 40/164 (24%), Positives = 78/164 (47%), Gaps = 9/164 (5%)
Frame = +3
Query: 84 ECENATSLSLM-IDSLLATYDRESPPD---SKIVVNLTLHLRH-ANIRESESTVRILADL 248
E + LSL ++L A Y++ P+ + + LTL + ++I ES L
Sbjct: 29 EVGRSDKLSLPGFENLTAGYNKFLRPNFGGEPVQIALTLDIASISSISESNMDYTATIYL 88
Query: 249 QMNWIDKRLSWNAGE-WGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNG 416
+ W+D+RL + + + LV E LW PD ++ + + + + R+ +NG
Sbjct: 89 RQRWMDQRLVFEGNKSFTLDARLV--EFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNG 146
Query: 417 SVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDF 548
+V + R+ + +M L +P D QTC + S ++ ++++F
Sbjct: 147 TVLYALRITTTVACNMDLSKYPMDTQTCKLQLESWGYDGNDVEF 190
>BC074865-1|AAH74865.1| 440|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, pi protein.
Length = 440
Score = 46.8 bits (106), Expect = 1e-04
Identities = 40/164 (24%), Positives = 78/164 (47%), Gaps = 9/164 (5%)
Frame = +3
Query: 84 ECENATSLSLM-IDSLLATYDRESPPD---SKIVVNLTLHLRH-ANIRESESTVRILADL 248
E + LSL ++L A Y++ P+ + + LTL + ++I ES L
Sbjct: 29 EVGRSDKLSLPGFENLTAGYNKFLRPNFGGEPVQIALTLDIASISSISESNMDYTATIYL 88
Query: 249 QMNWIDKRLSWNAGE-WGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNG 416
+ W+D+RL + + + LV E LW PD ++ + + + + R+ +NG
Sbjct: 89 RQRWMDQRLVFEGNKSFTLDARLV--EFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNG 146
Query: 417 SVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDF 548
+V + R+ + +M L +P D QTC + S ++ ++++F
Sbjct: 147 TVLYALRITTTVACNMDLSKYPMDTQTCKLQLESWGYDGNDVEF 190
>BC074810-1|AAH74810.1| 440|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, pi protein.
Length = 440
Score = 46.8 bits (106), Expect = 1e-04
Identities = 40/164 (24%), Positives = 78/164 (47%), Gaps = 9/164 (5%)
Frame = +3
Query: 84 ECENATSLSLM-IDSLLATYDRESPPD---SKIVVNLTLHLRH-ANIRESESTVRILADL 248
E + LSL ++L A Y++ P+ + + LTL + ++I ES L
Sbjct: 29 EVGRSDKLSLPGFENLTAGYNKFLRPNFGGEPVQIALTLDIASISSISESNMDYTATIYL 88
Query: 249 QMNWIDKRLSWNAGE-WGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNG 416
+ W+D+RL + + + LV E LW PD ++ + + + + R+ +NG
Sbjct: 89 RQRWMDQRLVFEGNKSFTLDARLV--EFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNG 146
Query: 417 SVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDF 548
+V + R+ + +M L +P D QTC + S ++ ++++F
Sbjct: 147 TVLYALRITTTVACNMDLSKYPMDTQTCKLQLESWGYDGNDVEF 190
>BC033801-1|AAH33801.1| 452|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, delta protein.
Length = 452
Score = 46.8 bits (106), Expect = 1e-04
Identities = 38/149 (25%), Positives = 64/149 (42%), Gaps = 7/149 (4%)
Frame = +3
Query: 117 IDSLLATYDRESPPD-SKIVVNLTLHLRHANI---RESESTVRILADLQMNWIDKRLSWN 284
+D L+A Y R P VN+ L L A+I E+ + L +W D RLS+N
Sbjct: 44 LDGLIAGYARNFRPGIGGPPVNVALALEVASIDHISEANMEYTMTVFLHQSWRDSRLSYN 103
Query: 285 AGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTP 455
++LW PD ++NA + D + R+ +G + + R+ +
Sbjct: 104 HTNETLGLDSRFVDKLWLPDTFIVNAKSAWFHDVTVENKLIRLQPDGVILYSIRITSTVA 163
Query: 456 ISMQLDNWPNDMQTCTFKFGSRMHNSDEM 542
M L +P D Q C S ++S+++
Sbjct: 164 CDMDLAKYPMDEQECMLDLESYGYSSEDI 192
>AL391845-4|CAI15436.1| 452|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, delta protein.
Length = 452
Score = 46.8 bits (106), Expect = 1e-04
Identities = 38/149 (25%), Positives = 64/149 (42%), Gaps = 7/149 (4%)
Frame = +3
Query: 117 IDSLLATYDRESPPD-SKIVVNLTLHLRHANI---RESESTVRILADLQMNWIDKRLSWN 284
+D L+A Y R P VN+ L L A+I E+ + L +W D RLS+N
Sbjct: 44 LDGLIAGYARNFRPGIGGPPVNVALALEVASIDHISEANMEYTMTVFLHQSWRDSRLSYN 103
Query: 285 AGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTP 455
++LW PD ++NA + D + R+ +G + + R+ +
Sbjct: 104 HTNETLGLDSRFVDKLWLPDTFIVNAKSAWFHDVTVENKLIRLQPDGVILYSIRITSTVA 163
Query: 456 ISMQLDNWPNDMQTCTFKFGSRMHNSDEM 542
M L +P D Q C S ++S+++
Sbjct: 164 CDMDLAKYPMDEQECMLDLESYGYSSEDI 192
>AF189259-1|AAF70380.1| 632|Homo sapiens GABA-A receptor theta
subunit protein.
Length = 632
Score = 46.8 bits (106), Expect = 1e-04
Identities = 35/145 (24%), Positives = 60/145 (41%), Gaps = 7/145 (4%)
Frame = +3
Query: 87 CENATSLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESESTVRILADLQM 254
C N + ++D +L+ YD P+ + + V +++++ I E I
Sbjct: 53 CANEAVVQKILDRVLSRYDVRLRPNFGGAPVPVRISIYVTSIEQISEMNMDYTITMFFHQ 112
Query: 255 NWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSN---NGSVS 425
W D RL++ + E+LW PD LN+ D + RV +G+V
Sbjct: 113 TWKDSRLAYYETTLNLTLDYRMHEKLWVPDCYFLNSKDAFVHDVTVENRVFQLHPDGTVR 172
Query: 426 WIKRLDISTPISMQLDNWPNDMQTC 500
+ RL + S+ L +P D Q C
Sbjct: 173 YGIRLTTTAACSLDLHKFPMDKQAC 197
>AF144648-1|AAD51172.1| 627|Homo sapiens GABA-A receptor theta
protein.
Length = 627
Score = 46.8 bits (106), Expect = 1e-04
Identities = 35/145 (24%), Positives = 60/145 (41%), Gaps = 7/145 (4%)
Frame = +3
Query: 87 CENATSLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESESTVRILADLQM 254
C N + ++D +L+ YD P+ + + V +++++ I E I
Sbjct: 48 CANEAVVQKILDRVLSRYDVRLRPNFGGAPVPVRISIYVTSIEQISEMNMDYTITMFFHQ 107
Query: 255 NWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSN---NGSVS 425
W D RL++ + E+LW PD LN+ D + RV +G+V
Sbjct: 108 TWKDSRLAYYETTLNLTLDYRMHEKLWVPDCYFLNSKDAFVHDVTVENRVFQLHPDGTVR 167
Query: 426 WIKRLDISTPISMQLDNWPNDMQTC 500
+ RL + S+ L +P D Q C
Sbjct: 168 YGIRLTTTAACSLDLHKFPMDKQAC 192
>AF016917-1|AAB70007.1| 452|Homo sapiens GABA-A receptor delta
subunit protein.
Length = 452
Score = 46.8 bits (106), Expect = 1e-04
Identities = 38/149 (25%), Positives = 64/149 (42%), Gaps = 7/149 (4%)
Frame = +3
Query: 117 IDSLLATYDRESPPD-SKIVVNLTLHLRHANI---RESESTVRILADLQMNWIDKRLSWN 284
+D L+A Y R P VN+ L L A+I E+ + L +W D RLS+N
Sbjct: 44 LDGLIAGYARNFRPGIGGPPVNVALALEVASIDHISEANMEYTMTVFLHQSWRDSRLSYN 103
Query: 285 AGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTP 455
++LW PD ++NA + D + R+ +G + + R+ +
Sbjct: 104 HTNETLGLDSRFVDKLWLPDTFIVNAKSAWFHDVTVENKLIRLQPDGVILYSIRITSTVA 163
Query: 456 ISMQLDNWPNDMQTCTFKFGSRMHNSDEM 542
M L +P D Q C S ++S+++
Sbjct: 164 CDMDLAKYPMDEQECMLDLESYGYSSEDI 192
>AF009702-1|AAC24194.1| 440|Homo sapiens GABA-A receptor pi subunit
protein.
Length = 440
Score = 46.8 bits (106), Expect = 1e-04
Identities = 40/164 (24%), Positives = 78/164 (47%), Gaps = 9/164 (5%)
Frame = +3
Query: 84 ECENATSLSLM-IDSLLATYDRESPPD---SKIVVNLTLHLRH-ANIRESESTVRILADL 248
E + LSL ++L A Y++ P+ + + LTL + ++I ES L
Sbjct: 29 EVGRSDKLSLPGFENLTAGYNKFLRPNFGGEPVQIALTLDIASISSISESNMDYTATIYL 88
Query: 249 QMNWIDKRLSWNAGE-WGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNG 416
+ W+D+RL + + + LV E LW PD ++ + + + + R+ +NG
Sbjct: 89 RQRWMDQRLVFEGNKSFTLDARLV--EFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNG 146
Query: 417 SVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDF 548
+V + R+ + +M L +P D QTC + S ++ ++++F
Sbjct: 147 TVLYALRITTTVACNMDLSKYPMDTQTCKLQLESWGYDGNDVEF 190
>BC096083-1|AAH96083.1| 198|Homo sapiens CHRNB4 protein protein.
Length = 198
Score = 46.4 bits (105), Expect = 1e-04
Identities = 30/115 (26%), Positives = 54/115 (46%), Gaps = 8/115 (6%)
Frame = +3
Query: 66 AIASAAECENATSLSLMIDSLL--ATYDRESPP--DSKIVVNLTLHLRHA---NIRESES 224
A+ C A + ++D LL Y+ P S ++++ L L A ++ E E
Sbjct: 14 ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQ 73
Query: 225 TVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDY 386
+ L+ W D RL+WN+ + G + + ++R+W PD+VL N + T +
Sbjct: 74 IMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNKSLRTGSTW 128
>BC096081-1|AAH96081.1| 198|Homo sapiens CHRNB4 protein protein.
Length = 198
Score = 46.4 bits (105), Expect = 1e-04
Identities = 30/115 (26%), Positives = 54/115 (46%), Gaps = 8/115 (6%)
Frame = +3
Query: 66 AIASAAECENATSLSLMIDSLL--ATYDRESPP--DSKIVVNLTLHLRHA---NIRESES 224
A+ C A + ++D LL Y+ P S ++++ L L A ++ E E
Sbjct: 14 ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQ 73
Query: 225 TVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDY 386
+ L+ W D RL+WN+ + G + + ++R+W PD+VL N + T +
Sbjct: 74 IMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNKSLRTGSTW 128
>BC074795-1|AAH74795.1| 467|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, gamma 2 protein.
Length = 467
Score = 46.0 bits (104), Expect = 2e-04
Identities = 38/178 (21%), Positives = 77/178 (43%), Gaps = 9/178 (5%)
Frame = +3
Query: 105 LSLMIDSLLATYDRESPPDSKI---VVNLTLHLRH---ANIRESESTVRILADLQMNWID 266
+++++++LL YD + PD + +++ +++ N E T+ I W D
Sbjct: 66 VTVILNNLLEGYDNKLRPDIGVKPTLIHTDMYVNSIGPVNAINMEYTIDIF--FAQTWYD 123
Query: 267 KRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYAL---RARVSNNGSVSWIKR 437
+RL +N+ ++W PD N+ A R+ N+G V + R
Sbjct: 124 RRLKFNSTIKVLRLNSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYTLR 183
Query: 438 LDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDKRIYSMFESGAWDVTDLS 611
L I +QL N+P D +C +F S + +E+ + + + ++ +W + S
Sbjct: 184 LTIDAECQLQLHNFPMDEHSCPLEFSSYGYPREEIVYQWKRSSVEVGDTRSWRLYQFS 241
>BC069348-1|AAH69348.1| 467|Homo sapiens gamma-aminobutyric acid A
receptor, gamma 2, isoform 2 precursor protein.
Length = 467
Score = 46.0 bits (104), Expect = 2e-04
Identities = 38/178 (21%), Positives = 77/178 (43%), Gaps = 9/178 (5%)
Frame = +3
Query: 105 LSLMIDSLLATYDRESPPDSKI---VVNLTLHLRH---ANIRESESTVRILADLQMNWID 266
+++++++LL YD + PD + +++ +++ N E T+ I W D
Sbjct: 66 VTVILNNLLEGYDNKLRPDIGVKPTLIHTDMYVNSIGPVNAINMEYTIDIF--FAQTWYD 123
Query: 267 KRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYAL---RARVSNNGSVSWIKR 437
+RL +N+ ++W PD N+ A R+ N+G V + R
Sbjct: 124 RRLKFNSTIKVLRLNSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYTLR 183
Query: 438 LDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDKRIYSMFESGAWDVTDLS 611
L I +QL N+P D +C +F S + +E+ + + + ++ +W + S
Sbjct: 184 LTIDAECQLQLHNFPMDEHSCPLEFSSYGYPREEIVYQWKRSSVEVGDTRSWRLYQFS 241
>BC059389-1|AAH59389.1| 475|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, gamma 2 protein.
Length = 475
Score = 46.0 bits (104), Expect = 2e-04
Identities = 38/178 (21%), Positives = 77/178 (43%), Gaps = 9/178 (5%)
Frame = +3
Query: 105 LSLMIDSLLATYDRESPPDSKI---VVNLTLHLRH---ANIRESESTVRILADLQMNWID 266
+++++++LL YD + PD + +++ +++ N E T+ I W D
Sbjct: 66 VTVILNNLLEGYDNKLRPDIGVKPTLIHTDMYVNSIGPVNAINMEYTIDIF--FAQTWYD 123
Query: 267 KRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYAL---RARVSNNGSVSWIKR 437
+RL +N+ ++W PD N+ A R+ N+G V + R
Sbjct: 124 RRLKFNSTIKVLRLNSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYTLR 183
Query: 438 LDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDKRIYSMFESGAWDVTDLS 611
L I +QL N+P D +C +F S + +E+ + + + ++ +W + S
Sbjct: 184 LTIDAECQLQLHNFPMDEHSCPLEFSSYGYPREEIVYQWKRSSVEVGDTRSWRLYQFS 241
>AF165124-1|AAD50273.1| 467|Homo sapiens gamma-aminobutyric acid A
receptor gamma 2 protein.
Length = 467
Score = 46.0 bits (104), Expect = 2e-04
Identities = 38/178 (21%), Positives = 77/178 (43%), Gaps = 9/178 (5%)
Frame = +3
Query: 105 LSLMIDSLLATYDRESPPDSKI---VVNLTLHLRH---ANIRESESTVRILADLQMNWID 266
+++++++LL YD + PD + +++ +++ N E T+ I W D
Sbjct: 66 VTVILNNLLEGYDNKLRPDIGVKPTLIHTDMYVNSIGPVNAINMEYTIDIF--FAQTWYD 123
Query: 267 KRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYAL---RARVSNNGSVSWIKR 437
+RL +N+ ++W PD N+ A R+ N+G V + R
Sbjct: 124 RRLKFNSTIKVLRLNSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYTLR 183
Query: 438 LDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDKRIYSMFESGAWDVTDLS 611
L I +QL N+P D +C +F S + +E+ + + + ++ +W + S
Sbjct: 184 LTIDAECQLQLHNFPMDEHSCPLEFSSYGYPREEIVYQWKRSSVEVGDTRSWRLYQFS 241
>X52009-1|CAA36258.1| 449|Homo sapiens inhibitory glycine receptor
protein.
Length = 449
Score = 45.6 bits (103), Expect = 2e-04
Identities = 48/188 (25%), Positives = 82/188 (43%), Gaps = 15/188 (7%)
Frame = +3
Query: 30 LYYSCYXFLLTCAIASAAEC-ENAT---SLSLMIDSLLAT---YDRESPPDSK-IVVNLT 185
LY S + A + AE +AT S S +D L+ YD P+ K VN++
Sbjct: 9 LYLSGAIVFFSLAASKEAEAARSATKPMSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVS 68
Query: 186 LHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERLWRPDVVL 353
++ +I E+ R+ L+ W D RL++N S + +W+PD+
Sbjct: 69 CNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYNEYPDDSLDLDPSMLDSIWKPDLFF 128
Query: 354 LNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRM 524
N + R+S NG+V + R+ ++ M L N+P D+QTC + S
Sbjct: 129 ANEKGAHFHEITTDNKLLRISRNGNVLYSIRITLTLACPMDLKNFPMDVQTCIMQLESFG 188
Query: 525 HNSDEMDF 548
+ +++ F
Sbjct: 189 YTMNDLIF 196
>X15376-1|CAA33437.1| 467|Homo sapiens GABA-A receptor gamma 2
subunit protein.
Length = 467
Score = 45.2 bits (102), Expect = 3e-04
Identities = 40/178 (22%), Positives = 79/178 (44%), Gaps = 9/178 (5%)
Frame = +3
Query: 105 LSLMIDSLLATYDRESPPDSKI---VVNLTLHLRH---ANIRESESTVRILADLQMNWID 266
+++++++LL YD + PD + +++ +++ N E T+ I QM W D
Sbjct: 66 VTVILNNLLEGYDNKLRPDIGVKPTLIHTDMYVNSIGPVNAINMEYTIDIFF-AQM-WYD 123
Query: 267 KRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYAL---RARVSNNGSVSWIKR 437
+RL +N+ ++W PD N+ A R+ N+G V + R
Sbjct: 124 RRLKFNSTIKVLRLNSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYSLR 183
Query: 438 LDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDKRIYSMFESGAWDVTDLS 611
L I +QL N+P D +C +F S + +E+ + + + ++ +W + S
Sbjct: 184 LTIDAECQLQLHNFPMDEHSCPLEFSSYGYPREEIVYQWKRSSVEVGDTRSWRLYQFS 241
>BC031087-1|AAH31087.1| 465|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, gamma 1 protein.
Length = 465
Score = 45.2 bits (102), Expect = 3e-04
Identities = 39/172 (22%), Positives = 74/172 (43%), Gaps = 9/172 (5%)
Frame = +3
Query: 105 LSLMIDSLLATYDRESPPDSKI---VVNLTLHLRHANIRES---ESTVRILADLQMNWID 266
++ +++SLL YD + PD + V+ +++ + E T+ I+ W D
Sbjct: 64 ITQILNSLLQGYDNKLRPDIGVRPTVIETDVYVNSIGPVDPINMEYTIDII--FAQTWFD 121
Query: 267 KRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKR 437
RL +N+ ++W PD N+ + A R+ N+G V + R
Sbjct: 122 SRLKFNSTMKVLMLNSNMVGKIWIPDTFFRNSRKSDAHWITTPNRLLRIWNDGRVLYTLR 181
Query: 438 LDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDKRIYSMFESGAW 593
L I+ +QL N+P D +C +F S + +E+++ K + + W
Sbjct: 182 LTINAECYLQLHNFPMDEHSCPLEFSSYGYPKNEIEYKWKKPSVEVADPKYW 233
>BC114947-1|AAI14948.1| 457|Homo sapiens GLRA1 protein protein.
Length = 457
Score = 44.8 bits (101), Expect = 4e-04
Identities = 30/119 (25%), Positives = 54/119 (45%), Gaps = 4/119 (3%)
Frame = +3
Query: 204 NIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERLWRPDVVLLNAAATTAG 380
+I E+ R+ L+ W D RL++N S + +W+PD+ N
Sbjct: 78 SIAETTMDYRVNIFLRQQWNDPRLAYNEYPDDSLDLDPSMLDSIWKPDLFFANEKGAHFH 137
Query: 381 DYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDF 548
+ R+S NG+V + R+ ++ M L N+P D+QTC + S + +++ F
Sbjct: 138 EITTDNKLLRISRNGNVLYSIRITLTLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIF 196
>BC074980-1|AAH74980.1| 449|Homo sapiens glycine receptor, alpha 1
(startle disease/hyperekplexia) protein.
Length = 449
Score = 44.8 bits (101), Expect = 4e-04
Identities = 30/119 (25%), Positives = 54/119 (45%), Gaps = 4/119 (3%)
Frame = +3
Query: 204 NIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERLWRPDVVLLNAAATTAG 380
+I E+ R+ L+ W D RL++N S + +W+PD+ N
Sbjct: 78 SIAETTMDYRVNIFLRQQWNDPRLAYNEYPDDSLDLDPSMLDSIWKPDLFFANEKGAHFH 137
Query: 381 DYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDF 548
+ R+S NG+V + R+ ++ M L N+P D+QTC + S + +++ F
Sbjct: 138 EITTDNKLLRISRNGNVLYSIRITLTLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIF 196
>AB209359-1|BAD92596.1| 533|Homo sapiens cholinergic receptor,
nicotinic, alpha polypeptide 4 precursor variant
protein.
Length = 533
Score = 44.0 bits (99), Expect = 7e-04
Identities = 26/95 (27%), Positives = 44/95 (46%), Gaps = 3/95 (3%)
Frame = +3
Query: 330 LWRPDVVLLNAAATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFK 509
LW +A A + +A + ++G V W + S+ + +P D Q CT K
Sbjct: 25 LWLCCCTFTSADGDFAVTHLTKAHLFHDGRVQWTPPAIYKSSCSIDVTFFPFDQQNCTMK 84
Query: 510 FGSRMHNSDEMDFV-IDKRI--YSMFESGAWDVTD 605
FGS ++ ++D V + R+ +ESG W + D
Sbjct: 85 FGSWTYDKAKIDLVNMHSRVDQLDFWESGEWVIVD 119
>Z93848-1|CAI41994.1| 376|Homo sapiens glycine receptor, alpha 4
protein.
Length = 376
Score = 43.6 bits (98), Expect = 0.001
Identities = 37/145 (25%), Positives = 63/145 (43%), Gaps = 8/145 (5%)
Frame = +3
Query: 138 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 305
YD P+ K VN+T ++ ++I ++ R+ L+ W D RLS+
Sbjct: 17 YDARIRPNFKGPPVNVTCNIFINSFSSITKTTMDYRVNVFLRQQWNDPRLSYREYPDDSL 76
Query: 306 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLD 473
S + +W+PD+ N + R+ NG+V + RL + M L
Sbjct: 77 DLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLILSCLMDLK 136
Query: 474 NWPNDMQTCTFKFGSRMHNSDEMDF 548
N+P D+QTCT + S + ++ F
Sbjct: 137 NFPMDIQTCTMQLESFGYTMKDLVF 161
>U93917-1|AAC39917.1| 449|Homo sapiens glycine receptor alpha 3
subunit protein.
Length = 449
Score = 43.6 bits (98), Expect = 0.001
Identities = 36/145 (24%), Positives = 64/145 (44%), Gaps = 8/145 (5%)
Frame = +3
Query: 138 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 305
YD P+ K VN+T ++ +I E+ R+ L+ W D RL+++
Sbjct: 57 YDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPDDSL 116
Query: 306 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLD 473
S + +W+PD+ N + R+ NG+V + RL ++ M L
Sbjct: 117 DLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLK 176
Query: 474 NWPNDMQTCTFKFGSRMHNSDEMDF 548
N+P D+QTC + S + +++ F
Sbjct: 177 NFPMDVQTCIMQLESFGYTMNDLIF 201
>BC036086-1|AAH36086.1| 464|Homo sapiens glycine receptor, alpha 3
protein.
Length = 464
Score = 43.6 bits (98), Expect = 0.001
Identities = 36/145 (24%), Positives = 64/145 (44%), Gaps = 8/145 (5%)
Frame = +3
Query: 138 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 305
YD P+ K VN+T ++ +I E+ R+ L+ W D RL+++
Sbjct: 57 YDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPDDSL 116
Query: 306 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLD 473
S + +W+PD+ N + R+ NG+V + RL ++ M L
Sbjct: 117 DLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLK 176
Query: 474 NWPNDMQTCTFKFGSRMHNSDEMDF 548
N+P D+QTC + S + +++ F
Sbjct: 177 NFPMDVQTCIMQLESFGYTMNDLIF 201
>AL049610-1|CAI42158.1| 376|Homo sapiens glycine receptor, alpha 4
protein.
Length = 376
Score = 43.6 bits (98), Expect = 0.001
Identities = 37/145 (25%), Positives = 63/145 (43%), Gaps = 8/145 (5%)
Frame = +3
Query: 138 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 305
YD P+ K VN+T ++ ++I ++ R+ L+ W D RLS+
Sbjct: 17 YDARIRPNFKGPPVNVTCNIFINSFSSITKTTMDYRVNVFLRQQWNDPRLSYREYPDDSL 76
Query: 306 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLD 473
S + +W+PD+ N + R+ NG+V + RL + M L
Sbjct: 77 DLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLILSCLMDLK 136
Query: 474 NWPNDMQTCTFKFGSRMHNSDEMDF 548
N+P D+QTCT + S + ++ F
Sbjct: 137 NFPMDIQTCTMQLESFGYTMKDLVF 161
>AF017724-1|AAC39919.1| 465|Homo sapiens glycine receptor alpha 3
subunit protein.
Length = 465
Score = 43.6 bits (98), Expect = 0.001
Identities = 36/145 (24%), Positives = 64/145 (44%), Gaps = 8/145 (5%)
Frame = +3
Query: 138 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 305
YD P+ K VN+T ++ +I E+ R+ L+ W D RL+++
Sbjct: 57 YDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPDDSL 116
Query: 306 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLD 473
S + +W+PD+ N + R+ NG+V + RL ++ M L
Sbjct: 117 DLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLK 176
Query: 474 NWPNDMQTCTFKFGSRMHNSDEMDF 548
N+P D+QTC + S + +++ F
Sbjct: 177 NFPMDVQTCIMQLESFGYTMNDLIF 201
>BC096291-1|AAH96291.1| 556|Homo sapiens CHRNA4 protein protein.
Length = 556
Score = 43.2 bits (97), Expect = 0.001
Identities = 25/83 (30%), Positives = 43/83 (51%), Gaps = 7/83 (8%)
Frame = +3
Query: 378 GDYAL----RARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 545
GD+A+ +A + ++G V W + S+ + +P D Q CT KFGS ++ ++D
Sbjct: 60 GDFAVTHLTKAHLFHDGRVQWTPPAIYKSSCSIDVTFFPFDQQNCTMKFGSWTYDKAKID 119
Query: 546 FV-IDKRI--YSMFESGAWDVTD 605
V + R+ +ESG W + D
Sbjct: 120 LVNMHSRVDQLDFWESGEWVIVD 142
>BC114967-1|AAI14968.1| 366|Homo sapiens GLRA1 protein protein.
Length = 366
Score = 42.3 bits (95), Expect = 0.002
Identities = 28/110 (25%), Positives = 50/110 (45%), Gaps = 4/110 (3%)
Frame = +3
Query: 231 RILADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERLWRPDVVLLNAAATTAGDYALR---A 398
R+ L+ W D RL++N S + +W+PD+ N +
Sbjct: 4 RVNIFLRQQWNDPRLAYNEYPDDSLDLDPSMLDSIWKPDLFFANEKGAHFHEITTDNKLL 63
Query: 399 RVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDF 548
R+S NG+V + R+ ++ M L N+P D+QTC + S + +++ F
Sbjct: 64 RISRNGNVLYSIRITLTLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIF 113
>BC146774-1|AAI46775.1| 1114|Homo sapiens GPR124 protein protein.
Length = 1114
Score = 30.7 bits (66), Expect = 6.9
Identities = 16/55 (29%), Positives = 26/55 (47%), Gaps = 1/55 (1%)
Frame = +3
Query: 279 WNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNN-GSVSWIKRL 440
W +GEW C+ + + ++V+L T+ Y RV+NN G W + L
Sbjct: 314 WASGEWECTVSMAQGNASKKVEIVVLE----TSASYCPAERVANNRGDFRWPRTL 364
>AY181242-1|AAO27354.1| 1331|Homo sapiens G protein-coupled receptor
124 protein.
Length = 1331
Score = 30.7 bits (66), Expect = 6.9
Identities = 16/55 (29%), Positives = 26/55 (47%), Gaps = 1/55 (1%)
Frame = +3
Query: 279 WNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNN-GSVSWIKRL 440
W +GEW C+ + + ++V+L T+ Y RV+NN G W + L
Sbjct: 314 WASGEWECTVSMAQGNASKKVEIVVLE----TSASYCPAERVANNRGDFRWPRTL 364
>AK074099-1|BAB84925.1| 1310|Homo sapiens FLJ00170 protein protein.
Length = 1310
Score = 30.7 bits (66), Expect = 6.9
Identities = 16/55 (29%), Positives = 26/55 (47%), Gaps = 1/55 (1%)
Frame = +3
Query: 279 WNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNN-GSVSWIKRL 440
W +GEW C+ + + ++V+L T+ Y RV+NN G W + L
Sbjct: 293 WASGEWECTVSMAQGNASKKVEIVVLE----TSASYCPAERVANNRGDFRWPRTL 343
>AF378755-1|AAL11992.1| 1331|Homo sapiens tumor endothelial marker 5
precursor protein.
Length = 1331
Score = 30.7 bits (66), Expect = 6.9
Identities = 16/55 (29%), Positives = 26/55 (47%), Gaps = 1/55 (1%)
Frame = +3
Query: 279 WNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNN-GSVSWIKRL 440
W +GEW C+ + + ++V+L T+ Y RV+NN G W + L
Sbjct: 314 WASGEWECTVSMAQGNASKKVEIVVLE----TSASYCPAERVANNRGDFRWPRTL 364
>AB040964-1|BAA96055.2| 1206|Homo sapiens KIAA1531 protein protein.
Length = 1206
Score = 30.7 bits (66), Expect = 6.9
Identities = 16/55 (29%), Positives = 26/55 (47%), Gaps = 1/55 (1%)
Frame = +3
Query: 279 WNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNN-GSVSWIKRL 440
W +GEW C+ + + ++V+L T+ Y RV+NN G W + L
Sbjct: 406 WASGEWECTVSMAQGNASKKVEIVVLE----TSASYCPAERVANNRGDFRWPRTL 456
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 115,317,397
Number of Sequences: 237096
Number of extensions: 2697648
Number of successful extensions: 7114
Number of sequences better than 10.0: 183
Number of HSP's better than 10.0 without gapping: 6405
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 6953
length of database: 76,859,062
effective HSP length: 89
effective length of database: 55,757,518
effective search space used: 10649685938
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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