Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BmNP05_FL5_L01
(867 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
AJ306454-1|CAC34819.1| 497|Homo sapiens neuronal nicotinic acet... 81 4e-15
Y08416-1|CAA69693.1| 498|Homo sapiens nicotinic acetylcholine r... 79 2e-14
U62439-1|AAB40117.1| 498|Homo sapiens nicotinic acetylcholine r... 79 2e-14
U48861-1|AAA92123.1| 498|Homo sapiens beta 4 nicotinic acetylch... 79 2e-14
BC096082-1|AAH96082.1| 498|Homo sapiens cholinergic receptor, n... 79 2e-14
BC096080-1|AAH96080.1| 498|Homo sapiens cholinergic receptor, n... 79 2e-14
AF306329-1|AAL02062.1| 498|Homo sapiens neuronal nicotinic acet... 79 2e-14
X68275-1|CAA48336.1| 451|Homo sapiens nicotinic receptor beta 4... 76 2e-13
BT006897-1|AAP35543.1| 505|Homo sapiens cholinergic receptor, n... 76 2e-13
BT006646-1|AAP35292.1| 489|Homo sapiens cholinergic receptor, n... 76 2e-13
BC006114-1|AAH06114.1| 489|Homo sapiens CHRNA3 protein protein. 76 2e-13
BC002996-1|AAH02996.1| 505|Homo sapiens cholinergic receptor, n... 76 2e-13
BC001642-1|AAH01642.1| 505|Homo sapiens cholinergic receptor, n... 76 2e-13
BC000513-1|AAH00513.1| 505|Homo sapiens cholinergic receptor, n... 76 2e-13
AF385584-1|AAK68110.1| 489|Homo sapiens nicotinic cholinergic r... 76 2e-13
Y08418-1|CAA69695.1| 503|Homo sapiens nicotinic acetylcholine r... 74 6e-13
U62432-1|AAB40110.1| 504|Homo sapiens nicotinic acetylcholine r... 74 6e-13
M37981-1|AAA59942.1| 503|Homo sapiens neuronal nicotinic acetyl... 74 6e-13
BC098443-1|AAH98443.1| 504|Homo sapiens cholinergic receptor, n... 74 6e-13
AJ007783-1|CAA07682.1| 504|Homo sapiens nicotinic acetylcholine... 74 6e-13
Y08419-1|CAA69696.1| 468|Homo sapiens nicotinic acetylcholine r... 73 2e-12
U62434-1|AAB40112.1| 468|Homo sapiens nicotinic acetylcholine r... 73 2e-12
BC033639-1|AAH33639.1| 468|Homo sapiens cholinergic receptor, n... 73 2e-12
AJ306481-1|CAC34820.1| 468|Homo sapiens neuronal nicotinic acet... 73 2e-12
X53559-1|CAA37625.1| 474|Homo sapiens neuronal nicotinic acetyl... 72 3e-12
M86383-1|AAC84176.1| 502|Homo sapiens nicotinic acetylcholine r... 72 3e-12
Y08417-1|CAA69694.1| 458|Homo sapiens nicotinic acetylcholine r... 71 4e-12
X67513-1|CAA47851.1| 423|Homo sapiens nicotinic acetylcholine ... 71 4e-12
U62438-1|AAB40116.1| 458|Homo sapiens nicotinic acetylcholine r... 71 4e-12
M83712-1|AAA58357.1| 468|Homo sapiens nicotinic receptor alpha ... 71 4e-12
BC069788-1|AAH69788.1| 458|Homo sapiens cholinergic receptor, n... 71 4e-12
BC069703-1|AAH69703.1| 458|Homo sapiens cholinergic receptor, n... 71 4e-12
BC069681-1|AAH69681.1| 458|Homo sapiens cholinergic receptor, n... 71 4e-12
AF140765-1|AAD33063.1| 458|Homo sapiens neuronal acetylcholine ... 71 4e-12
AJ001935-1|CAA05108.1| 504|Homo sapiens CHRNB2 protein. 70 1e-11
Y16281-1|CAA76154.1| 529|Homo sapiens nicotinic acetylcholine r... 70 1e-11
Y08415-1|CAA69692.1| 502|Homo sapiens nicotinic acetylcholine r... 70 1e-11
X53179-1|CAA37320.1| 502|Homo sapiens precursor peptide (AA -25... 70 1e-11
U62437-1|AAB40115.1| 502|Homo sapiens nicotinic acetylcholine r... 70 1e-11
U62431-1|AAB40109.1| 529|Homo sapiens nicotinic acetylcholine r... 70 1e-11
BC075041-1|AAH75041.1| 502|Homo sapiens cholinergic receptor, n... 70 1e-11
BC075040-1|AAH75040.1| 502|Homo sapiens cholinergic receptor, n... 70 1e-11
AL592078-3|CAI16184.1| 502|Homo sapiens cholinergic receptor, n... 70 1e-11
AF077186-1|AAD45422.1| 502|Homo sapiens neuronal nicotinic acet... 70 1e-11
Y08421-1|CAA69698.1| 627|Homo sapiens nicotinic acetylcholine r... 67 7e-11
X89741-1|CAA61893.1| 627|Homo sapiens neuronal acetylcholine re... 67 7e-11
U62433-1|AAB40111.1| 627|Homo sapiens nicotinic acetylcholine r... 67 7e-11
L35901-1|AAA64743.1| 627|Homo sapiens nicotinic acetylcholine r... 67 7e-11
DQ093071-1|AAY88737.1| 627|Homo sapiens cholinergic receptor, n... 67 7e-11
BC096290-1|AAH96290.1| 627|Homo sapiens cholinergic receptor, n... 67 7e-11
X87629-1|CAA60959.1| 602|Homo sapiens nicotinic acetylcholine r... 67 9e-11
Y16282-1|CAA76155.1| 494|Homo sapiens nicotinic acetylcholine r... 64 6e-10
U62435-1|AAB40113.1| 494|Homo sapiens nicotinic acetylcholine r... 64 6e-10
BC014456-1|AAH14456.1| 494|Homo sapiens cholinergic receptor, n... 64 6e-10
AB079251-1|BAC06855.1| 494|Homo sapiens Nicotinic acetylcholine... 64 6e-10
X14830-1|CAA32939.1| 501|Homo sapiens protein ( Human mRNA for ... 62 3e-09
BC011371-1|AAH11371.1| 501|Homo sapiens cholinergic receptor, n... 62 3e-09
BC023553-1|AAH23553.1| 501|Homo sapiens cholinergic receptor, n... 61 6e-09
Y00762-1|CAA68731.1| 457|Homo sapiens protein ( Human mRNA for ... 60 8e-09
X02502-1|CAA26344.1| 457|Homo sapiens acetylcholine receptor pr... 60 8e-09
S77094-1|AAD14247.1| 457|Homo sapiens nicotinic acetylcholine r... 60 8e-09
BC006314-1|AAH06314.1| 269|Homo sapiens CHRNA1 protein protein. 60 8e-09
AC018890-1|AAY14687.1| 457|Homo sapiens unknown protein. 60 8e-09
BC113575-1|AAI13576.1| 479|Homo sapiens cholinergic receptor, n... 59 2e-08
BC113549-1|AAI13550.1| 479|Homo sapiens cholinergic receptor, n... 59 2e-08
AY123244-1|AAM74523.1| 479|Homo sapiens nicotinic acetylcholine... 59 2e-08
AJ243342-1|CAB65091.1| 479|Homo sapiens nicotinic acetylcholine... 59 2e-08
AF227732-1|AAF61920.1| 470|Homo sapiens nicotinic acetylcholine... 59 2e-08
AC118275-1|AAY40986.1| 479|Homo sapiens unknown protein. 59 2e-08
BC131799-1|AAI31800.1| 447|Homo sapiens 5-hydroxytryptamine (se... 58 3e-08
X66403-1|CAA47030.1| 493|Homo sapiens acetylcholine receptor ep... 58 4e-08
AF459285-1|AAL66182.1| 447|Homo sapiens 5-hydroxytryptamine rec... 58 4e-08
AF105999-1|AAD24503.1| 493|Homo sapiens acetylcholine receptor ... 58 4e-08
AJ295237-1|CAC16144.1| 450|Homo sapiens neuronal nicotinic acet... 57 7e-08
AJ278118-1|CAC20435.1| 450|Homo sapiens neuronal nicotinic acet... 57 7e-08
AF327367-1|AAK14333.1| 450|Homo sapiens nicotinic acetylcholine... 57 7e-08
AF199235-1|AAG00795.2| 450|Homo sapiens nicotinic acetylcholine... 57 7e-08
X01715-1|CAA25861.1| 520|Homo sapiens acetylcholine receptor ga... 57 1e-07
S82769-1|AAB39369.1| 467|Homo sapiens GABAA receptor gamma 3 su... 57 1e-07
AF269144-1|AAF99698.1| 467|Homo sapiens GABAA receptor gamma 3 ... 57 1e-07
AF228458-1|AAF63215.1| 449|Homo sapiens GABAA receptor gamma 3 ... 57 1e-07
AC092165-3|AAY24103.1| 520|Homo sapiens unknown protein. 57 1e-07
M59216-1|AAA35862.1| 474|Homo sapiens gamma-aminobutyric acid r... 56 2e-07
DQ644022-1|ABG35128.1| 456|Homo sapiens 5-HT3 receptor subunit ... 56 2e-07
BC101185-1|AAI01186.1| 374|Homo sapiens HTR3E protein protein. 56 2e-07
BC101183-1|AAI01184.1| 471|Homo sapiens 5-hydroxytryptamine (se... 56 2e-07
BC101182-1|AAI01183.1| 471|Homo sapiens 5-hydroxytryptamine (se... 56 2e-07
AY349353-1|AAQ93477.1| 456|Homo sapiens 5-HT3c1 serotonin recep... 56 2e-07
AY349352-1|AAQ93476.1| 441|Homo sapiens 5-HT3c1 serotonin recep... 56 2e-07
AY159813-1|AAO38167.2| 471|Homo sapiens 5-hydroxytryptamine ser... 56 2e-07
X14767-1|CAA32875.1| 474|Homo sapiens GABA-A receptor beta 1 su... 55 3e-07
L08485-1|AAA58490.1| 462|Homo sapiens GABA-benzodiazepine recep... 55 3e-07
BT009830-1|AAP88832.1| 462|Homo sapiens gamma-aminobutyric acid... 55 3e-07
BC113422-1|AAI13423.1| 462|Homo sapiens gamma-aminobutyric acid... 55 3e-07
BC111979-1|AAI11980.1| 462|Homo sapiens gamma-aminobutyric acid... 55 3e-07
S82612-1|AAB37533.2| 478|Homo sapiens 5-hydroxytryptamine type ... 55 4e-07
S77554-1|AAB33983.1| 474|Homo sapiens GABAA receptor beta 2 sub... 55 4e-07
S77553-1|AAB33982.1| 512|Homo sapiens GABAA receptor beta 2 sub... 55 4e-07
S67368-1|AAB29370.1| 474|Homo sapiens gamma-aminobutyric acid A... 55 4e-07
BC105639-1|AAI05640.1| 474|Homo sapiens GABRB2 protein protein. 55 4e-07
BC099719-1|AAH99719.1| 474|Homo sapiens GABRB2 protein protein. 55 4e-07
BC099705-1|AAH99705.1| 474|Homo sapiens GABRB2 protein protein. 55 4e-07
AJ003080-1|CAA05853.1| 238|Homo sapiens serotonin receptor prot... 55 4e-07
D49394-1|BAA08387.1| 478|Homo sapiens serotonin 5-HT3 receptor ... 54 7e-07
BT007204-1|AAP35868.1| 484|Homo sapiens 5-hydroxytryptamine (se... 54 7e-07
BC004453-1|AAH04453.2| 478|Homo sapiens 5-hydroxytryptamine (se... 54 7e-07
BC002354-1|AAH02354.1| 478|Homo sapiens 5-hydroxytryptamine (se... 54 7e-07
AJ005205-1|CAA06442.3| 478|Homo sapiens serotonin 3 receptor pr... 54 7e-07
AJ003079-1|CAA05852.1| 478|Homo sapiens 5-hydroxytryptamine3 re... 54 7e-07
AJ003078-1|CAA05851.1| 510|Homo sapiens serotonin receptor prot... 54 7e-07
AF498984-1|AAM21131.1| 478|Homo sapiens 5-hydroxytryptamine rec... 54 7e-07
S81944-1|AAB36480.1| 453|Homo sapiens gamma-aminobutyric acid t... 52 2e-06
BC099641-1|AAH99641.1| 453|Homo sapiens gamma-aminobutyric acid... 52 2e-06
BC099640-1|AAH99640.1| 453|Homo sapiens gamma-aminobutyric acid... 52 2e-06
BC096242-1|AAH96242.1| 453|Homo sapiens gamma-aminobutyric acid... 52 2e-06
BC096241-1|AAH96241.1| 453|Homo sapiens gamma-aminobutyric acid... 52 2e-06
BC028629-1|AAH28629.1| 492|Homo sapiens gamma-aminobutyric acid... 52 2e-06
X55019-1|CAA38759.1| 517|Homo sapiens acetylcholine receptor de... 52 3e-06
S62908-1|AAB27279.1| 492|Homo sapiens gamma-aminobutyric acidA ... 52 3e-06
BC093925-1|AAH93925.1| 517|Homo sapiens cholinergic receptor, n... 52 3e-06
BC093923-1|AAH93923.1| 517|Homo sapiens cholinergic receptor, n... 52 3e-06
AF166361-1|AAG12455.1| 492|Homo sapiens GABA receptor subunit a... 52 3e-06
AC092165-2|AAY24102.1| 517|Homo sapiens unknown protein. 52 3e-06
Z23141-1|CAA80672.1| 479|Homo sapiens cholinergic receptor, nic... 52 4e-06
Y08420-1|CAA69697.1| 502|Homo sapiens nicotinic acetylcholine r... 52 4e-06
X70297-1|CAA49778.1| 502|Homo sapiens neuronal nicotinic acetyl... 52 4e-06
U62436-1|AAB40114.1| 502|Homo sapiens nicotinic acetylcholine r... 52 4e-06
AJ586911-1|CAE52911.1| 502|Homo sapiens nicotinic acetylcholine... 52 4e-06
U30461-1|AAB52519.1| 554|Homo sapiens GABAA receptor subunit al... 51 5e-06
BC110597-1|AAI10598.1| 411|Homo sapiens ligand-gated ion channe... 51 5e-06
BC035055-1|AAH35055.1| 554|Homo sapiens gamma-aminobutyric acid... 51 5e-06
AF512521-1|AAO20969.1| 411|Homo sapiens ligand-gated ion channe... 51 5e-06
BC022449-1|AAH22449.1| 474|Homo sapiens gamma-aminobutyric acid... 51 6e-06
AB223030-1|BAE19924.1| 411|Homo sapiens ligand-gated ion-channe... 51 6e-06
U95367-1|AAC51357.1| 440|Homo sapiens GABA-A receptor pi subuni... 50 8e-06
BC109106-1|AAI09107.1| 440|Homo sapiens gamma-aminobutyric acid... 50 8e-06
BC109105-1|AAI09106.1| 440|Homo sapiens gamma-aminobutyric acid... 50 8e-06
BC074865-1|AAH74865.1| 440|Homo sapiens gamma-aminobutyric acid... 50 8e-06
BC074810-1|AAH74810.1| 440|Homo sapiens gamma-aminobutyric acid... 50 8e-06
AF009702-1|AAC24194.1| 440|Homo sapiens GABA-A receptor pi subu... 50 8e-06
U40583-1|AAA83561.1| 502|Homo sapiens alpha 7 neuronal nicotini... 50 1e-05
BC033801-1|AAH33801.1| 452|Homo sapiens gamma-aminobutyric acid... 50 1e-05
AL391845-4|CAI15436.1| 452|Homo sapiens gamma-aminobutyric acid... 50 1e-05
AF385585-1|AAK68111.1| 502|Homo sapiens nicotinic cholinergic r... 50 1e-05
AF016917-1|AAB70007.1| 452|Homo sapiens GABA-A receptor delta s... 50 1e-05
BC074795-1|AAH74795.1| 467|Homo sapiens gamma-aminobutyric acid... 49 2e-05
BC069348-1|AAH69348.1| 467|Homo sapiens gamma-aminobutyric acid... 49 2e-05
BC059389-1|AAH59389.1| 475|Homo sapiens gamma-aminobutyric acid... 49 2e-05
AF165124-1|AAD50273.1| 467|Homo sapiens gamma-aminobutyric acid... 49 2e-05
X52008-1|CAA36257.1| 452|Homo sapiens inhibitory glycine recept... 48 3e-05
U77731-2|AAB38273.1| 360|Homo sapiens glycine receptor alpha 2B... 48 3e-05
U77731-1|AAB38272.1| 360|Homo sapiens glycine receptor alpha 2 ... 48 3e-05
CR450343-1|CAG29339.1| 452|Homo sapiens GLRA2 protein. 48 3e-05
BC032864-1|AAH32864.1| 452|Homo sapiens glycine receptor, alpha... 48 3e-05
AY437084-1|AAR87843.1| 452|Homo sapiens glycine receptor alpha2... 48 3e-05
AY437083-1|AAR87842.1| 452|Homo sapiens glycine receptor alpha2... 48 3e-05
AF053495-1|AAC35290.1| 452|Homo sapiens glycine receptor alpha ... 48 3e-05
X15376-1|CAA33437.1| 467|Homo sapiens GABA-A receptor gamma 2 s... 48 4e-05
BC111802-1|AAI11803.1| 465|Homo sapiens CHRNG protein protein. 48 6e-05
AK122638-1|BAC85499.1| 266|Homo sapiens yte protein of 76kDa) (... 48 6e-05
BC031087-1|AAH31087.1| 465|Homo sapiens gamma-aminobutyric acid... 47 8e-05
BC109211-1|AAI09212.1| 632|Homo sapiens gamma-aminobutyric acid... 46 1e-04
BC109210-1|AAI09211.1| 632|Homo sapiens gamma-aminobutyric acid... 46 1e-04
AF189259-1|AAF70380.1| 632|Homo sapiens GABA-A receptor theta s... 46 1e-04
AF144648-1|AAD51172.1| 627|Homo sapiens GABA-A receptor theta p... 46 1e-04
Y09763-1|CAA70903.1| 506|Homo sapiens GABRE protein. 46 2e-04
BC096083-1|AAH96083.1| 198|Homo sapiens CHRNB4 protein protein. 46 2e-04
BC096081-1|AAH96081.1| 198|Homo sapiens CHRNB4 protein protein. 46 2e-04
X52009-1|CAA36258.1| 449|Homo sapiens inhibitory glycine recept... 45 4e-04
BC114947-1|AAI14948.1| 457|Homo sapiens GLRA1 protein protein. 45 4e-04
BC074980-1|AAH74980.1| 449|Homo sapiens glycine receptor, alpha... 45 4e-04
Y09765-1|CAA70904.1| 506|Homo sapiens GABA receptor epsilon sub... 44 7e-04
U93917-1|AAC39917.1| 449|Homo sapiens glycine receptor alpha 3 ... 44 7e-04
U92283-1|AAB94645.1| 506|Homo sapiens GABA-A receptor epsilon s... 44 7e-04
BC036086-1|AAH36086.1| 464|Homo sapiens glycine receptor, alpha... 44 7e-04
AF017724-1|AAC39919.1| 465|Homo sapiens glycine receptor alpha ... 44 7e-04
Y07637-1|CAA68914.1| 505|Homo sapiens putative GABA-gated chlor... 44 0.001
U66661-1|AAB49284.1| 506|Homo sapiens GABA-A receptor epsilon s... 44 0.001
BC059376-1|AAH59376.1| 365|Homo sapiens GABRE protein protein. 44 0.001
BC047108-1|AAH47108.1| 365|Homo sapiens GABRE protein protein. 44 0.001
BC026337-1|AAH26337.1| 365|Homo sapiens GABRE protein protein. 44 0.001
Z93848-1|CAI41994.1| 376|Homo sapiens glycine receptor, alpha 4... 41 0.007
BC114967-1|AAI14968.1| 366|Homo sapiens GLRA1 protein protein. 41 0.007
BC096291-1|AAH96291.1| 556|Homo sapiens CHRNA4 protein protein. 41 0.007
AL049610-1|CAI42158.1| 376|Homo sapiens glycine receptor, alpha... 41 0.007
AB209359-1|BAD92596.1| 533|Homo sapiens cholinergic receptor, n... 41 0.007
>AJ306454-1|CAC34819.1| 497|Homo sapiens neuronal nicotinic
acetylcholine receptor beta-4 subunit protein.
Length = 497
Score = 81.4 bits (192), Expect = 4e-15
Identities = 58/200 (29%), Positives = 95/200 (47%), Gaps = 9/200 (4%)
Frame = +1
Query: 64 LLPFLLTCAIASAAECENATSLSLMIDSLL--ATYDRDSPP--DSKIVVNLTLHLRHAN- 228
L+ F L A+ C A + ++D LL Y+ P S ++++ L L A
Sbjct: 7 LVLFFLV-ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQL 65
Query: 229 IRESESTVRIQADLQMLQNWIDKRLSWNAGEW-GCSTWLVSSERLWGPDVVLLNAAATTA 405
I +E + ++ + Q W D RL+WN+ + G + + ++R+W PD+VL N T
Sbjct: 66 ISVNEREQIMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNDGTYE 125
Query: 406 GDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVID 585
V +NGSV W+ + +++ +P D Q CT KF S ++ E+D V+
Sbjct: 126 VSVYTNLIVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRSWTYDHTEIDMVLM 185
Query: 586 KRIYSMFE---SGAWDVTAL 636
SM + SG WD+ AL
Sbjct: 186 TPTASMDDFTPSGEWDIVAL 205
>Y08416-1|CAA69693.1| 498|Homo sapiens nicotinic acetylcholine
receptor beta4 subunit precursor protein.
Length = 498
Score = 79.4 bits (187), Expect = 2e-14
Identities = 59/201 (29%), Positives = 96/201 (47%), Gaps = 10/201 (4%)
Frame = +1
Query: 64 LLPFLLTCAIASAAECENATSLSLMIDSLL--ATYDRDSPP--DSKIVVNLTLHLRHAN- 228
L+ F L A+ C A + ++D LL Y+ P S ++++ L L A
Sbjct: 7 LVLFFLV-ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQL 65
Query: 229 IRESESTVRIQADLQMLQNWIDKRLSWNAGEW-GCSTWLVSSERLWGPDVVLLNAA-ATT 402
I +E + ++ + Q W D RL+WN+ + G + + ++R+W PD+VL N A T
Sbjct: 66 ISVNEREQIMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNADGTY 125
Query: 403 AGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVI 582
V +NGSV W+ + +++ +P D Q CT KF S ++ E+D V+
Sbjct: 126 EVSVYTNLIVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRSWTYDHTEIDMVL 185
Query: 583 DKRIYSMFE---SGAWDVTAL 636
SM + SG WD+ AL
Sbjct: 186 MTPTASMDDFTPSGEWDIVAL 206
>U62439-1|AAB40117.1| 498|Homo sapiens nicotinic acetylcholine
receptor beta4 subunit precursor protein.
Length = 498
Score = 79.4 bits (187), Expect = 2e-14
Identities = 59/201 (29%), Positives = 96/201 (47%), Gaps = 10/201 (4%)
Frame = +1
Query: 64 LLPFLLTCAIASAAECENATSLSLMIDSLL--ATYDRDSPP--DSKIVVNLTLHLRHAN- 228
L+ F L A+ C A + ++D LL Y+ P S ++++ L L A
Sbjct: 7 LVLFFLV-ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQL 65
Query: 229 IRESESTVRIQADLQMLQNWIDKRLSWNAGEW-GCSTWLVSSERLWGPDVVLLNAA-ATT 402
I +E + ++ + Q W D RL+WN+ + G + + ++R+W PD+VL N A T
Sbjct: 66 ISVNEREQIMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNADGTY 125
Query: 403 AGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVI 582
V +NGSV W+ + +++ +P D Q CT KF S ++ E+D V+
Sbjct: 126 EVSVYTNLIVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRSWTYDHTEIDMVL 185
Query: 583 DKRIYSMFE---SGAWDVTAL 636
SM + SG WD+ AL
Sbjct: 186 MTPTASMDDFTPSGEWDIVAL 206
>U48861-1|AAA92123.1| 498|Homo sapiens beta 4 nicotinic
acetylcholine receptor subunit protein.
Length = 498
Score = 79.4 bits (187), Expect = 2e-14
Identities = 59/201 (29%), Positives = 96/201 (47%), Gaps = 10/201 (4%)
Frame = +1
Query: 64 LLPFLLTCAIASAAECENATSLSLMIDSLL--ATYDRDSPP--DSKIVVNLTLHLRHAN- 228
L+ F L A+ C A + ++D LL Y+ P S ++++ L L A
Sbjct: 7 LVLFFLV-ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQL 65
Query: 229 IRESESTVRIQADLQMLQNWIDKRLSWNAGEW-GCSTWLVSSERLWGPDVVLLNAA-ATT 402
I +E + ++ + Q W D RL+WN+ + G + + ++R+W PD+VL N A T
Sbjct: 66 ISVNEREQIMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNADGTY 125
Query: 403 AGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVI 582
V +NGSV W+ + +++ +P D Q CT KF S ++ E+D V+
Sbjct: 126 EVSVYTNLIVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRSWTYDHTEIDMVL 185
Query: 583 DKRIYSMFE---SGAWDVTAL 636
SM + SG WD+ AL
Sbjct: 186 MTPTASMDDFTPSGEWDIVAL 206
>BC096082-1|AAH96082.1| 498|Homo sapiens cholinergic receptor,
nicotinic, beta 4 protein.
Length = 498
Score = 79.4 bits (187), Expect = 2e-14
Identities = 59/201 (29%), Positives = 96/201 (47%), Gaps = 10/201 (4%)
Frame = +1
Query: 64 LLPFLLTCAIASAAECENATSLSLMIDSLL--ATYDRDSPP--DSKIVVNLTLHLRHAN- 228
L+ F L A+ C A + ++D LL Y+ P S ++++ L L A
Sbjct: 7 LVLFFLV-ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQL 65
Query: 229 IRESESTVRIQADLQMLQNWIDKRLSWNAGEW-GCSTWLVSSERLWGPDVVLLNAA-ATT 402
I +E + ++ + Q W D RL+WN+ + G + + ++R+W PD+VL N A T
Sbjct: 66 ISVNEREQIMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNADGTY 125
Query: 403 AGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVI 582
V +NGSV W+ + +++ +P D Q CT KF S ++ E+D V+
Sbjct: 126 EVSVYTNLIVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRSWTYDHTEIDMVL 185
Query: 583 DKRIYSMFE---SGAWDVTAL 636
SM + SG WD+ AL
Sbjct: 186 MTPTASMDDFTPSGEWDIVAL 206
>BC096080-1|AAH96080.1| 498|Homo sapiens cholinergic receptor,
nicotinic, beta 4 protein.
Length = 498
Score = 79.4 bits (187), Expect = 2e-14
Identities = 59/201 (29%), Positives = 96/201 (47%), Gaps = 10/201 (4%)
Frame = +1
Query: 64 LLPFLLTCAIASAAECENATSLSLMIDSLL--ATYDRDSPP--DSKIVVNLTLHLRHAN- 228
L+ F L A+ C A + ++D LL Y+ P S ++++ L L A
Sbjct: 7 LVLFFLV-ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQL 65
Query: 229 IRESESTVRIQADLQMLQNWIDKRLSWNAGEW-GCSTWLVSSERLWGPDVVLLNAA-ATT 402
I +E + ++ + Q W D RL+WN+ + G + + ++R+W PD+VL N A T
Sbjct: 66 ISVNEREQIMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNADGTY 125
Query: 403 AGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVI 582
V +NGSV W+ + +++ +P D Q CT KF S ++ E+D V+
Sbjct: 126 EVSVYTNLIVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRSWTYDHTEIDMVL 185
Query: 583 DKRIYSMFE---SGAWDVTAL 636
SM + SG WD+ AL
Sbjct: 186 MTPTASMDDFTPSGEWDIVAL 206
>AF306329-1|AAL02062.1| 498|Homo sapiens neuronal nicotinic
acetylcholine receptor beta 4 subunit protein.
Length = 498
Score = 79.4 bits (187), Expect = 2e-14
Identities = 59/201 (29%), Positives = 96/201 (47%), Gaps = 10/201 (4%)
Frame = +1
Query: 64 LLPFLLTCAIASAAECENATSLSLMIDSLL--ATYDRDSPP--DSKIVVNLTLHLRHAN- 228
L+ F L A+ C A + ++D LL Y+ P S ++++ L L A
Sbjct: 7 LVLFFLV-ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQL 65
Query: 229 IRESESTVRIQADLQMLQNWIDKRLSWNAGEW-GCSTWLVSSERLWGPDVVLLNAA-ATT 402
I +E + ++ + Q W D RL+WN+ + G + + ++R+W PD+VL N A T
Sbjct: 66 ISVNEREQIMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNADGTY 125
Query: 403 AGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVI 582
V +NGSV W+ + +++ +P D Q CT KF S ++ E+D V+
Sbjct: 126 EVSVYTNLIVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRSWTYDHTEIDMVL 185
Query: 583 DKRIYSMFE---SGAWDVTAL 636
SM + SG WD+ AL
Sbjct: 186 MTPTASMDDFTPSGEWDIVAL 206
>X68275-1|CAA48336.1| 451|Homo sapiens nicotinic receptor beta 4
subunit protein.
Length = 451
Score = 75.8 bits (178), Expect = 2e-13
Identities = 48/157 (30%), Positives = 79/157 (50%), Gaps = 6/157 (3%)
Frame = +1
Query: 184 SKIVVNLTLHLRHAN-IRESESTVRIQADLQMLQNWIDKRLSWNAGEW-GCSTWLVSSER 357
S ++++ L L A I +E + ++ + Q W D RL+WN+ + G + + ++R
Sbjct: 3 SSQLISIKLQLSLAQLISVNERDEIMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKR 62
Query: 358 LWGPDVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTF 534
+W PD+VL N A T V +NGSV W+ + +++ +P D Q CT
Sbjct: 63 IWLPDIVLYNNADGTYEVSVYTNLIVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTL 122
Query: 535 KFGSRMHNSDEMDFVIDKRIYSMFE---SGAWDVTAL 636
KF S ++ E+D V+ SM + SG WD+ AL
Sbjct: 123 KFRSWTYDHTEIDMVLMTPTASMDDFTPSGEWDIVAL 159
>BT006897-1|AAP35543.1| 505|Homo sapiens cholinergic receptor,
nicotinic, alpha polypeptide 3 protein.
Length = 505
Score = 75.8 bits (178), Expect = 2e-13
Identities = 50/203 (24%), Positives = 96/203 (47%), Gaps = 8/203 (3%)
Frame = +1
Query: 43 MSTTYIILLPFLLTCAIASAAECENATSLSLMIDSLLATYDRDSPPDSKIVVNLTLHLRH 222
+S ++LL L +A A+E E+ + + L Y+ P + + + +H
Sbjct: 12 LSPPRLLLLLLLSLLPVARASEAEHR-----LFERLFEDYNEIIRPVANVSDPVIIHFEV 66
Query: 223 AN---IRESESTVRIQADLQMLQNWIDKRLSWNAGEWGCSTWL-VSSERLWGPDVVLLN- 387
+ ++ E ++ +L + Q W D +L WN ++G + ++ V ++++W PD+VL N
Sbjct: 67 SMSQLVKVDEVNQIMETNLWLKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNN 126
Query: 388 AAATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDE 567
A D +A + G V+WI + + + +P D Q CT KFGS ++ +
Sbjct: 127 AVGDFQVDDKTKALLKYTGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAK 186
Query: 568 MDFVI---DKRIYSMFESGAWDV 627
+D V+ + +ESG W +
Sbjct: 187 IDLVLIGSSMNLKDYWESGEWAI 209
>BT006646-1|AAP35292.1| 489|Homo sapiens cholinergic receptor,
nicotinic, alpha polypeptide 3 protein.
Length = 489
Score = 75.8 bits (178), Expect = 2e-13
Identities = 50/203 (24%), Positives = 96/203 (47%), Gaps = 8/203 (3%)
Frame = +1
Query: 43 MSTTYIILLPFLLTCAIASAAECENATSLSLMIDSLLATYDRDSPPDSKIVVNLTLHLRH 222
+S ++LL L +A A+E E+ + + L Y+ P + + + +H
Sbjct: 12 LSPPRLLLLLLLSLLPVARASEAEHR-----LFERLFEDYNEIIRPVANVSDPVIIHFEV 66
Query: 223 AN---IRESESTVRIQADLQMLQNWIDKRLSWNAGEWGCSTWL-VSSERLWGPDVVLLN- 387
+ ++ E ++ +L + Q W D +L WN ++G + ++ V ++++W PD+VL N
Sbjct: 67 SMSQLVKVDEVNQIMETNLWLKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNN 126
Query: 388 AAATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDE 567
A D +A + G V+WI + + + +P D Q CT KFGS ++ +
Sbjct: 127 AVGDFQVDDKTKALLKYTGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAK 186
Query: 568 MDFVI---DKRIYSMFESGAWDV 627
+D V+ + +ESG W +
Sbjct: 187 IDLVLIGSSMNLKDYWESGEWAI 209
>BC006114-1|AAH06114.1| 489|Homo sapiens CHRNA3 protein protein.
Length = 489
Score = 75.8 bits (178), Expect = 2e-13
Identities = 50/203 (24%), Positives = 96/203 (47%), Gaps = 8/203 (3%)
Frame = +1
Query: 43 MSTTYIILLPFLLTCAIASAAECENATSLSLMIDSLLATYDRDSPPDSKIVVNLTLHLRH 222
+S ++LL L +A A+E E+ + + L Y+ P + + + +H
Sbjct: 12 LSPPRLLLLLLLSLLPVARASEAEHR-----LFERLFEDYNEIIRPVANVSDPVIIHFEV 66
Query: 223 AN---IRESESTVRIQADLQMLQNWIDKRLSWNAGEWGCSTWL-VSSERLWGPDVVLLN- 387
+ ++ E ++ +L + Q W D +L WN ++G + ++ V ++++W PD+VL N
Sbjct: 67 SMSQLVKVDEVNQIMETNLWLKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNN 126
Query: 388 AAATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDE 567
A D +A + G V+WI + + + +P D Q CT KFGS ++ +
Sbjct: 127 AVGDFQVDDKTKALLKYTGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAK 186
Query: 568 MDFVI---DKRIYSMFESGAWDV 627
+D V+ + +ESG W +
Sbjct: 187 IDLVLIGSSMNLKDYWESGEWAI 209
>BC002996-1|AAH02996.1| 505|Homo sapiens cholinergic receptor,
nicotinic, alpha 3 protein.
Length = 505
Score = 75.8 bits (178), Expect = 2e-13
Identities = 50/203 (24%), Positives = 96/203 (47%), Gaps = 8/203 (3%)
Frame = +1
Query: 43 MSTTYIILLPFLLTCAIASAAECENATSLSLMIDSLLATYDRDSPPDSKIVVNLTLHLRH 222
+S ++LL L +A A+E E+ + + L Y+ P + + + +H
Sbjct: 12 LSPPRLLLLLLLSLLPVARASEAEHR-----LFERLFEDYNEIIRPVANVSDPVIIHFEV 66
Query: 223 AN---IRESESTVRIQADLQMLQNWIDKRLSWNAGEWGCSTWL-VSSERLWGPDVVLLN- 387
+ ++ E ++ +L + Q W D +L WN ++G + ++ V ++++W PD+VL N
Sbjct: 67 SMSQLVKVDEVNQIMETNLWLKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNN 126
Query: 388 AAATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDE 567
A D +A + G V+WI + + + +P D Q CT KFGS ++ +
Sbjct: 127 AVGDFQVDDKTKALLKYTGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAK 186
Query: 568 MDFVI---DKRIYSMFESGAWDV 627
+D V+ + +ESG W +
Sbjct: 187 IDLVLIGSSMNLKDYWESGEWAI 209
>BC001642-1|AAH01642.1| 505|Homo sapiens cholinergic receptor,
nicotinic, alpha 3 protein.
Length = 505
Score = 75.8 bits (178), Expect = 2e-13
Identities = 50/203 (24%), Positives = 96/203 (47%), Gaps = 8/203 (3%)
Frame = +1
Query: 43 MSTTYIILLPFLLTCAIASAAECENATSLSLMIDSLLATYDRDSPPDSKIVVNLTLHLRH 222
+S ++LL L +A A+E E+ + + L Y+ P + + + +H
Sbjct: 12 LSPPRLLLLLLLSLLPVARASEAEHR-----LFERLFEDYNEIIRPVANVSDPVIIHFEV 66
Query: 223 AN---IRESESTVRIQADLQMLQNWIDKRLSWNAGEWGCSTWL-VSSERLWGPDVVLLN- 387
+ ++ E ++ +L + Q W D +L WN ++G + ++ V ++++W PD+VL N
Sbjct: 67 SMSQLVKVDEVNQIMETNLWLKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNN 126
Query: 388 AAATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDE 567
A D +A + G V+WI + + + +P D Q CT KFGS ++ +
Sbjct: 127 AVGDFQVDDKTKALLKYTGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAK 186
Query: 568 MDFVI---DKRIYSMFESGAWDV 627
+D V+ + +ESG W +
Sbjct: 187 IDLVLIGSSMNLKDYWESGEWAI 209
>BC000513-1|AAH00513.1| 505|Homo sapiens cholinergic receptor,
nicotinic, alpha 3 protein.
Length = 505
Score = 75.8 bits (178), Expect = 2e-13
Identities = 50/203 (24%), Positives = 96/203 (47%), Gaps = 8/203 (3%)
Frame = +1
Query: 43 MSTTYIILLPFLLTCAIASAAECENATSLSLMIDSLLATYDRDSPPDSKIVVNLTLHLRH 222
+S ++LL L +A A+E E+ + + L Y+ P + + + +H
Sbjct: 12 LSPPRLLLLLLLSLLPVARASEAEHR-----LFERLFEDYNEIIRPVANVSDPVIIHFEV 66
Query: 223 AN---IRESESTVRIQADLQMLQNWIDKRLSWNAGEWGCSTWL-VSSERLWGPDVVLLN- 387
+ ++ E ++ +L + Q W D +L WN ++G + ++ V ++++W PD+VL N
Sbjct: 67 SMSQLVKVDEVNQIMETNLWLKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNN 126
Query: 388 AAATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDE 567
A D +A + G V+WI + + + +P D Q CT KFGS ++ +
Sbjct: 127 AVGDFQVDDKTKALLKYTGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAK 186
Query: 568 MDFVI---DKRIYSMFESGAWDV 627
+D V+ + +ESG W +
Sbjct: 187 IDLVLIGSSMNLKDYWESGEWAI 209
>AF385584-1|AAK68110.1| 489|Homo sapiens nicotinic cholinergic
receptor alpha 3 protein.
Length = 489
Score = 75.8 bits (178), Expect = 2e-13
Identities = 50/203 (24%), Positives = 96/203 (47%), Gaps = 8/203 (3%)
Frame = +1
Query: 43 MSTTYIILLPFLLTCAIASAAECENATSLSLMIDSLLATYDRDSPPDSKIVVNLTLHLRH 222
+S ++LL L +A A+E E+ + + L Y+ P + + + +H
Sbjct: 6 LSPPRLLLLLLLSLLPVARASEAEHR-----LFERLFEDYNEIIRPVANVSDPVIIHFEV 60
Query: 223 AN---IRESESTVRIQADLQMLQNWIDKRLSWNAGEWGCSTWL-VSSERLWGPDVVLLN- 387
+ ++ E ++ +L + Q W D +L WN ++G + ++ V ++++W PD+VL N
Sbjct: 61 SMSQLVKVDEVNQIMETNLWLKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNN 120
Query: 388 AAATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDE 567
A D +A + G V+WI + + + +P D Q CT KFGS ++ +
Sbjct: 121 AVGDFQVDDKTKALLKYTGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAK 180
Query: 568 MDFVI---DKRIYSMFESGAWDV 627
+D V+ + +ESG W +
Sbjct: 181 IDLVLIGSSMNLKDYWESGEWAI 203
>Y08418-1|CAA69695.1| 503|Homo sapiens nicotinic acetylcholine
receptor alpha3 subunit precursor protein.
Length = 503
Score = 74.1 bits (174), Expect = 6e-13
Identities = 49/197 (24%), Positives = 93/197 (47%), Gaps = 8/197 (4%)
Frame = +1
Query: 61 ILLPFLLTCAIASAAECENATSLSLMIDSLLATYDRDSPPDSKIVVNLTLHLRHAN---I 231
+LL L +A A+E E+ + + L Y+ P + + + +H + +
Sbjct: 16 LLLLLLSLLPVARASEAEHR-----LFERLFEDYNEIIRPVANVSDPVIIHFEVSMSQLV 70
Query: 232 RESESTVRIQADLQMLQNWIDKRLSWNAGEWGCSTWL-VSSERLWGPDVVLLN-AAATTA 405
+ E ++ +L + Q W D +L WN ++G + ++ V ++++W PD+VL N A
Sbjct: 71 KVDEVNQIMETNLWLKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQ 130
Query: 406 GDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVI- 582
D +A + G V+WI + + + +P D Q CT KFGS ++ ++D V+
Sbjct: 131 VDDKTKALLKYTGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVLI 190
Query: 583 --DKRIYSMFESGAWDV 627
+ +ESG W +
Sbjct: 191 GSSMNLKDYWESGEWAI 207
>U62432-1|AAB40110.1| 504|Homo sapiens nicotinic acetylcholine
receptor alpha3 subunit precursor protein.
Length = 504
Score = 74.1 bits (174), Expect = 6e-13
Identities = 49/197 (24%), Positives = 93/197 (47%), Gaps = 8/197 (4%)
Frame = +1
Query: 61 ILLPFLLTCAIASAAECENATSLSLMIDSLLATYDRDSPPDSKIVVNLTLHLRHAN---I 231
+LL L +A A+E E+ + + L Y+ P + + + +H + +
Sbjct: 17 LLLLLLSLLPVARASEAEHR-----LFERLFEDYNEIIRPVANVSDPVIIHFEVSMSQLV 71
Query: 232 RESESTVRIQADLQMLQNWIDKRLSWNAGEWGCSTWL-VSSERLWGPDVVLLN-AAATTA 405
+ E ++ +L + Q W D +L WN ++G + ++ V ++++W PD+VL N A
Sbjct: 72 KVDEVNQIMETNLWLKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQ 131
Query: 406 GDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVI- 582
D +A + G V+WI + + + +P D Q CT KFGS ++ ++D V+
Sbjct: 132 VDDKTKALLKYTGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVLI 191
Query: 583 --DKRIYSMFESGAWDV 627
+ +ESG W +
Sbjct: 192 GSSMNLKDYWESGEWAI 208
>M37981-1|AAA59942.1| 503|Homo sapiens neuronal nicotinic
acetylcholine receptor protein.
Length = 503
Score = 74.1 bits (174), Expect = 6e-13
Identities = 49/197 (24%), Positives = 93/197 (47%), Gaps = 8/197 (4%)
Frame = +1
Query: 61 ILLPFLLTCAIASAAECENATSLSLMIDSLLATYDRDSPPDSKIVVNLTLHLRHAN---I 231
+LL L +A A+E E+ + + L Y+ P + + + +H + +
Sbjct: 16 LLLLLLSLLPVARASEAEHR-----LFERLFEDYNEIIRPVANVSDPVIIHFEVSMSQLV 70
Query: 232 RESESTVRIQADLQMLQNWIDKRLSWNAGEWGCSTWL-VSSERLWGPDVVLLN-AAATTA 405
+ E ++ +L + Q W D +L WN ++G + ++ V ++++W PD+VL N A
Sbjct: 71 KVDEVNQIMETNLWLKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQ 130
Query: 406 GDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVI- 582
D +A + G V+WI + + + +P D Q CT KFGS ++ ++D V+
Sbjct: 131 VDDKTKALLKYTGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVLI 190
Query: 583 --DKRIYSMFESGAWDV 627
+ +ESG W +
Sbjct: 191 GSSMNLKDYWESGEWAI 207
>BC098443-1|AAH98443.1| 504|Homo sapiens cholinergic receptor,
nicotinic, alpha 3 protein.
Length = 504
Score = 74.1 bits (174), Expect = 6e-13
Identities = 49/197 (24%), Positives = 93/197 (47%), Gaps = 8/197 (4%)
Frame = +1
Query: 61 ILLPFLLTCAIASAAECENATSLSLMIDSLLATYDRDSPPDSKIVVNLTLHLRHAN---I 231
+LL L +A A+E E+ + + L Y+ P + + + +H + +
Sbjct: 17 LLLLLLSLLPVARASEAEHR-----LFERLFEDYNEIIRPVANVSDPVIIHFEVSMSQLV 71
Query: 232 RESESTVRIQADLQMLQNWIDKRLSWNAGEWGCSTWL-VSSERLWGPDVVLLN-AAATTA 405
+ E ++ +L + Q W D +L WN ++G + ++ V ++++W PD+VL N A
Sbjct: 72 KVDEVNQIMETNLWLKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQ 131
Query: 406 GDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVI- 582
D +A + G V+WI + + + +P D Q CT KFGS ++ ++D V+
Sbjct: 132 VDDKTKALLKYTGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVLI 191
Query: 583 --DKRIYSMFESGAWDV 627
+ +ESG W +
Sbjct: 192 GSSMNLKDYWESGEWAI 208
>AJ007783-1|CAA07682.1| 504|Homo sapiens nicotinic acetylcholine
receptor alpha-3 subunit protein.
Length = 504
Score = 74.1 bits (174), Expect = 6e-13
Identities = 49/197 (24%), Positives = 93/197 (47%), Gaps = 8/197 (4%)
Frame = +1
Query: 61 ILLPFLLTCAIASAAECENATSLSLMIDSLLATYDRDSPPDSKIVVNLTLHLRHAN---I 231
+LL L +A A+E E+ + + L Y+ P + + + +H + +
Sbjct: 17 LLLLLLSLLPVARASEAEHR-----LFERLFEDYNEIIRPVANVSDPVIIHFEVSMSQLV 71
Query: 232 RESESTVRIQADLQMLQNWIDKRLSWNAGEWGCSTWL-VSSERLWGPDVVLLN-AAATTA 405
+ E ++ +L + Q W D +L WN ++G + ++ V ++++W PD+VL N A
Sbjct: 72 KVDEVNQIMETNLWLKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQ 131
Query: 406 GDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVI- 582
D +A + G V+WI + + + +P D Q CT KFGS ++ ++D V+
Sbjct: 132 VDDKTKALLKYTGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVLI 191
Query: 583 --DKRIYSMFESGAWDV 627
+ +ESG W +
Sbjct: 192 GSSMNLKDYWESGEWAI 208
>Y08419-1|CAA69696.1| 468|Homo sapiens nicotinic acetylcholine
receptor alpha5 subunit precursor protein.
Length = 468
Score = 72.5 bits (170), Expect = 2e-12
Identities = 36/137 (26%), Positives = 71/137 (51%), Gaps = 6/137 (4%)
Frame = +1
Query: 241 ESTVRIQADLQMLQNWIDKRLSWNAGEWG-CSTWLVSSERLWGPDVVLLNAAATTAGDYA 417
E + ++ + Q WID +L WN ++G V S+ +W PD+VL + A +
Sbjct: 88 EKNQLMTTNVWLKQEWIDVKLRWNPDDYGGIKVIRVPSDSVWTPDIVLFDNADGRFEGTS 147
Query: 418 LRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFV-----I 582
+ + NG+V+W + + ++ + +P D+Q C+ KFGS ++ ++D + +
Sbjct: 148 TKTVIRYNGTVTWTPPANYKSSCTIDVTFFPFDLQNCSMKFGSWTYDGSQVDIILEDQDV 207
Query: 583 DKRIYSMFESGAWDVTA 633
DKR F++G W++ +
Sbjct: 208 DKR--DFFDNGEWEIVS 222
>U62434-1|AAB40112.1| 468|Homo sapiens nicotinic acetylcholine
receptor alpha5 subunit precursor protein.
Length = 468
Score = 72.5 bits (170), Expect = 2e-12
Identities = 36/137 (26%), Positives = 71/137 (51%), Gaps = 6/137 (4%)
Frame = +1
Query: 241 ESTVRIQADLQMLQNWIDKRLSWNAGEWG-CSTWLVSSERLWGPDVVLLNAAATTAGDYA 417
E + ++ + Q WID +L WN ++G V S+ +W PD+VL + A +
Sbjct: 88 EKNQLMTTNVWLKQEWIDVKLRWNPDDYGGIKVIRVPSDSVWTPDIVLFDNADGRFEGTS 147
Query: 418 LRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFV-----I 582
+ + NG+V+W + + ++ + +P D+Q C+ KFGS ++ ++D + +
Sbjct: 148 TKTVIRYNGTVTWTPPANYKSSCTIDVTFFPFDLQNCSMKFGSWTYDGSQVDIILEDQDV 207
Query: 583 DKRIYSMFESGAWDVTA 633
DKR F++G W++ +
Sbjct: 208 DKR--DFFDNGEWEIVS 222
>BC033639-1|AAH33639.1| 468|Homo sapiens cholinergic receptor,
nicotinic, alpha 5 protein.
Length = 468
Score = 72.5 bits (170), Expect = 2e-12
Identities = 36/137 (26%), Positives = 71/137 (51%), Gaps = 6/137 (4%)
Frame = +1
Query: 241 ESTVRIQADLQMLQNWIDKRLSWNAGEWG-CSTWLVSSERLWGPDVVLLNAAATTAGDYA 417
E + ++ + Q WID +L WN ++G V S+ +W PD+VL + A +
Sbjct: 88 EKNQLMTTNVWLKQEWIDVKLRWNPDDYGGIKVIRVPSDSVWTPDIVLFDNADGRFEGTS 147
Query: 418 LRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFV-----I 582
+ + NG+V+W + + ++ + +P D+Q C+ KFGS ++ ++D + +
Sbjct: 148 TKTVIRYNGTVTWTPPANYKSSCTIDVTFFPFDLQNCSMKFGSWTYDGSQVDIILEDQDV 207
Query: 583 DKRIYSMFESGAWDVTA 633
DKR F++G W++ +
Sbjct: 208 DKR--DFFDNGEWEIVS 222
>AJ306481-1|CAC34820.1| 468|Homo sapiens neuronal nicotinic
acetylcholine receptor alpha-5subunit protein.
Length = 468
Score = 72.5 bits (170), Expect = 2e-12
Identities = 36/137 (26%), Positives = 71/137 (51%), Gaps = 6/137 (4%)
Frame = +1
Query: 241 ESTVRIQADLQMLQNWIDKRLSWNAGEWG-CSTWLVSSERLWGPDVVLLNAAATTAGDYA 417
E + ++ + Q WID +L WN ++G V S+ +W PD+VL + A +
Sbjct: 88 EKNQLMTTNVWLKQEWIDVKLRWNPDDYGGIKVIRVPSDSVWTPDIVLFDNADGRFEGTS 147
Query: 418 LRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFV-----I 582
+ + NG+V+W + + ++ + +P D+Q C+ KFGS ++ ++D + +
Sbjct: 148 TKTVIRYNGTVTWTPPANYKSSCTIDVTFFPFDLQNCSMKFGSWTYDGSQVDIILEDQDV 207
Query: 583 DKRIYSMFESGAWDVTA 633
DKR F++G W++ +
Sbjct: 208 DKR--DFFDNGEWEIVS 222
>X53559-1|CAA37625.1| 474|Homo sapiens neuronal nicotinic
acetylcholine receptor alpha-3merase protein.
Length = 474
Score = 71.7 bits (168), Expect = 3e-12
Identities = 38/138 (27%), Positives = 70/138 (50%), Gaps = 5/138 (3%)
Frame = +1
Query: 229 IRESESTVRIQADLQMLQNWIDKRLSWNAGEWGCSTWL-VSSERLWGPDVVLLN-AAATT 402
++ E ++ +L + Q W D +L WN ++G + ++ V ++++W PD+VL N A
Sbjct: 41 VKVDEVNQIMETNLWLKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDF 100
Query: 403 AGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVI 582
D +A + G V+WI + + + +P D Q CT KFGS ++ ++D V+
Sbjct: 101 QVDDKTKALLKYTGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVL 160
Query: 583 ---DKRIYSMFESGAWDV 627
+ +ESG W +
Sbjct: 161 IGSSMNLKDYWESGEWAI 178
>M86383-1|AAC84176.1| 502|Homo sapiens nicotinic acetylcholine
receptor alpha 3 subunit precursor protein.
Length = 502
Score = 71.7 bits (168), Expect = 3e-12
Identities = 50/200 (25%), Positives = 95/200 (47%), Gaps = 11/200 (5%)
Frame = +1
Query: 61 ILLPFLLTCAIASAAECENATSLSLMIDSLLATYDRDSPPDSKIVVNLTLHLRHAN---I 231
+LL L +A A+E E+ + + L Y+ P + + + +H + +
Sbjct: 15 LLLLLLSLLPVARASEAEHR-----LFERLFEDYNEIIRPVANVSDPVIIHFEVSMSQLV 69
Query: 232 RESESTVRIQADLQMLQNWIDKRLSWNAGEWGCSTWL-VSSERLWGPDVVLLNAAATTAG 408
+ E ++ +L + Q W D +L WN +G + ++ V ++++W PD+VL N A G
Sbjct: 70 KVDEVNQIMETNLWLKQIWNDYKLKWNPSGYGGAEFMRVPAQKIWKPDIVLYNNAV---G 126
Query: 409 DYAL----RARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDF 576
D+ + +A + G V+WI + + + +P D Q CT KFGS ++ ++D
Sbjct: 127 DFQVTTKTKALLKYTGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDL 186
Query: 577 VI---DKRIYSMFESGAWDV 627
V+ + +ESG W +
Sbjct: 187 VLIGSSMNLKDYWESGEWAI 206
>Y08417-1|CAA69694.1| 458|Homo sapiens nicotinic acetylcholine
receptor beta3 subunit precursor protein.
Length = 458
Score = 71.3 bits (167), Expect = 4e-12
Identities = 39/134 (29%), Positives = 67/134 (50%), Gaps = 5/134 (3%)
Frame = +1
Query: 241 ESTVRIQADLQMLQNWIDKRLSWNAGEWG-CSTWLVSSERLWGPDVVLL-NAAATTAGDY 414
E + ++ + Q W D +L WN ++G + V SE LW PD+VL NA G
Sbjct: 70 EKNQLMTTNVWLKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFEGSL 129
Query: 415 ALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFV-IDKR 591
+ V +NG+V W + +M + +P D Q C+ KFGS ++ +D + I++
Sbjct: 130 MTKVIVKSNGTVVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGTMVDLILINEN 189
Query: 592 I--YSMFESGAWDV 627
+ F++G W++
Sbjct: 190 VDRKDFFDNGEWEI 203
>X67513-1|CAA47851.1| 423|Homo sapiens nicotinic acetylcholine
receptor beta-3 subunit protein.
Length = 423
Score = 71.3 bits (167), Expect = 4e-12
Identities = 39/134 (29%), Positives = 67/134 (50%), Gaps = 5/134 (3%)
Frame = +1
Query: 241 ESTVRIQADLQMLQNWIDKRLSWNAGEWG-CSTWLVSSERLWGPDVVLL-NAAATTAGDY 414
E + ++ + Q W D +L WN ++G + V SE LW PD+VL NA G
Sbjct: 35 EKNQLMTTNVWLKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFEGSL 94
Query: 415 ALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFV-IDKR 591
+ V +NG+V W + +M + +P D Q C+ KFGS ++ +D + I++
Sbjct: 95 MTKVIVKSNGTVVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGTMVDLILINEN 154
Query: 592 I--YSMFESGAWDV 627
+ F++G W++
Sbjct: 155 VDRKDFFDNGEWEI 168
>U62438-1|AAB40116.1| 458|Homo sapiens nicotinic acetylcholine
receptor beta3 subunit precursor protein.
Length = 458
Score = 71.3 bits (167), Expect = 4e-12
Identities = 39/134 (29%), Positives = 67/134 (50%), Gaps = 5/134 (3%)
Frame = +1
Query: 241 ESTVRIQADLQMLQNWIDKRLSWNAGEWG-CSTWLVSSERLWGPDVVLL-NAAATTAGDY 414
E + ++ + Q W D +L WN ++G + V SE LW PD+VL NA G
Sbjct: 70 EKNQLMTTNVWLKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFEGSL 129
Query: 415 ALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFV-IDKR 591
+ V +NG+V W + +M + +P D Q C+ KFGS ++ +D + I++
Sbjct: 130 MTKVIVKSNGTVVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGTMVDLILINEN 189
Query: 592 I--YSMFESGAWDV 627
+ F++G W++
Sbjct: 190 VDRKDFFDNGEWEI 203
>M83712-1|AAA58357.1| 468|Homo sapiens nicotinic receptor alpha 5
subunit protein.
Length = 468
Score = 71.3 bits (167), Expect = 4e-12
Identities = 36/137 (26%), Positives = 70/137 (51%), Gaps = 6/137 (4%)
Frame = +1
Query: 241 ESTVRIQADLQMLQNWIDKRLSWNAGEWG-CSTWLVSSERLWGPDVVLLNAAATTAGDYA 417
E + ++ + Q WID +L WN ++G V S+ W PD+VL + A +
Sbjct: 88 EKNQLMTTNVWLKQEWIDVKLRWNPDDYGGIKVIRVPSDSSWTPDIVLFDNADGRFEGTS 147
Query: 418 LRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFV-----I 582
+ + NG+V+W + + ++ + +P D+Q C+ KFGS ++ ++D + +
Sbjct: 148 TKTVIRYNGTVTWTPPANYKSSCTIDVTFFPFDLQNCSMKFGSWTYDGSQVDIILEDQDV 207
Query: 583 DKRIYSMFESGAWDVTA 633
DKR F++G W++ +
Sbjct: 208 DKR--DFFDNGEWEIVS 222
>BC069788-1|AAH69788.1| 458|Homo sapiens cholinergic receptor,
nicotinic, beta 3 protein.
Length = 458
Score = 71.3 bits (167), Expect = 4e-12
Identities = 39/134 (29%), Positives = 67/134 (50%), Gaps = 5/134 (3%)
Frame = +1
Query: 241 ESTVRIQADLQMLQNWIDKRLSWNAGEWG-CSTWLVSSERLWGPDVVLL-NAAATTAGDY 414
E + ++ + Q W D +L WN ++G + V SE LW PD+VL NA G
Sbjct: 70 EKNQLMTTNVWLKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFEGSL 129
Query: 415 ALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFV-IDKR 591
+ V +NG+V W + +M + +P D Q C+ KFGS ++ +D + I++
Sbjct: 130 MTKVIVKSNGTVVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGTMVDLILINEN 189
Query: 592 I--YSMFESGAWDV 627
+ F++G W++
Sbjct: 190 VDRKDFFDNGEWEI 203
>BC069703-1|AAH69703.1| 458|Homo sapiens cholinergic receptor,
nicotinic, beta 3 protein.
Length = 458
Score = 71.3 bits (167), Expect = 4e-12
Identities = 39/134 (29%), Positives = 67/134 (50%), Gaps = 5/134 (3%)
Frame = +1
Query: 241 ESTVRIQADLQMLQNWIDKRLSWNAGEWG-CSTWLVSSERLWGPDVVLL-NAAATTAGDY 414
E + ++ + Q W D +L WN ++G + V SE LW PD+VL NA G
Sbjct: 70 EKNQLMTTNVWLKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFEGSL 129
Query: 415 ALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFV-IDKR 591
+ V +NG+V W + +M + +P D Q C+ KFGS ++ +D + I++
Sbjct: 130 MTKVIVKSNGTVVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGTMVDLILINEN 189
Query: 592 I--YSMFESGAWDV 627
+ F++G W++
Sbjct: 190 VDRKDFFDNGEWEI 203
>BC069681-1|AAH69681.1| 458|Homo sapiens cholinergic receptor,
nicotinic, beta 3 protein.
Length = 458
Score = 71.3 bits (167), Expect = 4e-12
Identities = 39/134 (29%), Positives = 67/134 (50%), Gaps = 5/134 (3%)
Frame = +1
Query: 241 ESTVRIQADLQMLQNWIDKRLSWNAGEWG-CSTWLVSSERLWGPDVVLL-NAAATTAGDY 414
E + ++ + Q W D +L WN ++G + V SE LW PD+VL NA G
Sbjct: 70 EKNQLMTTNVWLKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFEGSL 129
Query: 415 ALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFV-IDKR 591
+ V +NG+V W + +M + +P D Q C+ KFGS ++ +D + I++
Sbjct: 130 MTKVIVKSNGTVVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGTMVDLILINEN 189
Query: 592 I--YSMFESGAWDV 627
+ F++G W++
Sbjct: 190 VDRKDFFDNGEWEI 203
>AF140765-1|AAD33063.1| 458|Homo sapiens neuronal acetylcholine
receptor beta-3 subunit precursor protein.
Length = 458
Score = 71.3 bits (167), Expect = 4e-12
Identities = 39/134 (29%), Positives = 67/134 (50%), Gaps = 5/134 (3%)
Frame = +1
Query: 241 ESTVRIQADLQMLQNWIDKRLSWNAGEWG-CSTWLVSSERLWGPDVVLL-NAAATTAGDY 414
E + ++ + Q W D +L WN ++G + V SE LW PD+VL NA G
Sbjct: 70 EKNQLMTTNVWLKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFEGSL 129
Query: 415 ALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFV-IDKR 591
+ V +NG+V W + +M + +P D Q C+ KFGS ++ +D + I++
Sbjct: 130 MTKVIVKSNGTVVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGTMVDLILINEN 189
Query: 592 I--YSMFESGAWDV 627
+ F++G W++
Sbjct: 190 VDRKDFFDNGEWEI 203
>AJ001935-1|CAA05108.1| 504|Homo sapiens CHRNB2 protein.
Length = 504
Score = 70.1 bits (164), Expect = 1e-11
Identities = 57/201 (28%), Positives = 94/201 (46%), Gaps = 9/201 (4%)
Frame = +1
Query: 61 ILLPF--LLTCAIASAAECENATSLSLMIDSLLATYDRDSPPDSKIV-VNLTLHLRHA-N 228
+LL F L C+ A+ E L+ S R + S++V V L + L +
Sbjct: 10 LLLGFGLLRLCSGVWGADTEERLVEHLLDPSRYNKLIRPATNGSELVTVQLMVSLAQLIS 69
Query: 229 IRESESTVRIQADLQMLQNWIDKRLSWNAGEW-GCSTWLVSSERLWGPDVVLLNAA-ATT 402
+ E E + ++ + Q W D RL+W E+ + S+ +W PDVVL N A
Sbjct: 70 VHEREQIMT--TNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLPDVVLYNNADGMY 127
Query: 403 AGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVI 582
+ A VS +GS+ W+ + +++ ++P D Q CT KF S ++ E+D V+
Sbjct: 128 EVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRSWTYDRTEIDLVL 187
Query: 583 DKRIYSMFE---SGAWDVTAL 636
+ S+ + SG WD+ AL
Sbjct: 188 KSEVASLDDFTPSGEWDIVAL 208
>Y16281-1|CAA76154.1| 529|Homo sapiens nicotinic acetylcholine
receptor alpha2 subunit precursor protein.
Length = 529
Score = 69.7 bits (163), Expect = 1e-11
Identities = 46/158 (29%), Positives = 79/158 (50%), Gaps = 8/158 (5%)
Frame = +1
Query: 178 PDSKIVVNLTLHLRHANIRE-SESTVRIQADLQMLQNWIDKRLSWNAGEWGCSTWL-VSS 351
P++ VV + L A + + E + ++ + Q W D +L WN ++G T L V S
Sbjct: 78 PNTSDVVIVRFGLSIAQLIDVDEKNQMMTTNVWLKQEWSDYKLRWNPADFGNITSLRVPS 137
Query: 352 ERLWGPDVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTC 528
E +W PD+VL N A A + +A + + G+V W+ + S+ + +P D Q C
Sbjct: 138 EMIWIPDIVLYNNADGEFAVTHMTKAHLFSTGTVHWVPPAIYKSSCSIDVTFFPFDQQNC 197
Query: 529 TFKFGSRMHNS-----DEMDFVIDKRIYSMFESGAWDV 627
KFGS ++ ++M+ +D + Y +ESG W +
Sbjct: 198 KMKFGSWTYDKAKIDLEQMEQTVDLKDY--WESGEWAI 233
>Y08415-1|CAA69692.1| 502|Homo sapiens nicotinic acetylcholine
receptor beta2 subunit precursor protein.
Length = 502
Score = 69.7 bits (163), Expect = 1e-11
Identities = 40/126 (31%), Positives = 64/126 (50%), Gaps = 5/126 (3%)
Frame = +1
Query: 274 MLQNWIDKRLSWNAGEW-GCSTWLVSSERLWGPDVVLLNAA-ATTAGDYALRARVSNNGS 447
+ Q W D RL+W E+ + S+ +W PDVVL N A + A VS +GS
Sbjct: 83 LTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLPDVVLYNNADGMYEVSFYSNAVVSYDGS 142
Query: 448 VSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDKRIYSMFE---SGA 618
+ W+ + +++ ++P D Q CT KF S ++ E+D V+ + S+ + SG
Sbjct: 143 IFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRSWTYDRTEIDLVLKSEVASLDDFTPSGE 202
Query: 619 WDVTAL 636
WD+ AL
Sbjct: 203 WDIVAL 208
>X53179-1|CAA37320.1| 502|Homo sapiens precursor peptide (AA -25 to
477) protein.
Length = 502
Score = 69.7 bits (163), Expect = 1e-11
Identities = 40/126 (31%), Positives = 64/126 (50%), Gaps = 5/126 (3%)
Frame = +1
Query: 274 MLQNWIDKRLSWNAGEW-GCSTWLVSSERLWGPDVVLLNAA-ATTAGDYALRARVSNNGS 447
+ Q W D RL+W E+ + S+ +W PDVVL N A + A VS +GS
Sbjct: 83 LTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLPDVVLYNNADGMYEVSFYSNAVVSYDGS 142
Query: 448 VSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDKRIYSMFE---SGA 618
+ W+ + +++ ++P D Q CT KF S ++ E+D V+ + S+ + SG
Sbjct: 143 IFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRSWTYDRTEIDLVLKSEVASLDDFTPSGE 202
Query: 619 WDVTAL 636
WD+ AL
Sbjct: 203 WDIVAL 208
>U62437-1|AAB40115.1| 502|Homo sapiens nicotinic acetylcholine
receptor beta2 subunit precursor protein.
Length = 502
Score = 69.7 bits (163), Expect = 1e-11
Identities = 40/126 (31%), Positives = 64/126 (50%), Gaps = 5/126 (3%)
Frame = +1
Query: 274 MLQNWIDKRLSWNAGEW-GCSTWLVSSERLWGPDVVLLNAA-ATTAGDYALRARVSNNGS 447
+ Q W D RL+W E+ + S+ +W PDVVL N A + A VS +GS
Sbjct: 83 LTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLPDVVLYNNADGMYEVSFYSNAVVSYDGS 142
Query: 448 VSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDKRIYSMFE---SGA 618
+ W+ + +++ ++P D Q CT KF S ++ E+D V+ + S+ + SG
Sbjct: 143 IFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRSWTYDRTEIDLVLKSEVASLDDFTPSGE 202
Query: 619 WDVTAL 636
WD+ AL
Sbjct: 203 WDIVAL 208
>U62431-1|AAB40109.1| 529|Homo sapiens nicotinic acetylcholine
receptor alpha2 subunit precursor protein.
Length = 529
Score = 69.7 bits (163), Expect = 1e-11
Identities = 46/158 (29%), Positives = 79/158 (50%), Gaps = 8/158 (5%)
Frame = +1
Query: 178 PDSKIVVNLTLHLRHANIRE-SESTVRIQADLQMLQNWIDKRLSWNAGEWGCSTWL-VSS 351
P++ VV + L A + + E + ++ + Q W D +L WN ++G T L V S
Sbjct: 78 PNTSDVVIVRFGLSIAQLIDVDEKNQMMTTNVWLKQEWSDYKLRWNPADFGNITSLRVPS 137
Query: 352 ERLWGPDVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTC 528
E +W PD+VL N A A + +A + + G+V W+ + S+ + +P D Q C
Sbjct: 138 EMIWIPDIVLYNNADGEFAVTHMTKAHLFSTGTVHWVPPAIYKSSCSIDVTFFPFDQQNC 197
Query: 529 TFKFGSRMHNS-----DEMDFVIDKRIYSMFESGAWDV 627
KFGS ++ ++M+ +D + Y +ESG W +
Sbjct: 198 KMKFGSWTYDKAKIDLEQMEQTVDLKDY--WESGEWAI 233
>BC075041-1|AAH75041.1| 502|Homo sapiens cholinergic receptor,
nicotinic, beta 2 (neuronal) protein.
Length = 502
Score = 69.7 bits (163), Expect = 1e-11
Identities = 40/126 (31%), Positives = 64/126 (50%), Gaps = 5/126 (3%)
Frame = +1
Query: 274 MLQNWIDKRLSWNAGEW-GCSTWLVSSERLWGPDVVLLNAA-ATTAGDYALRARVSNNGS 447
+ Q W D RL+W E+ + S+ +W PDVVL N A + A VS +GS
Sbjct: 83 LTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLPDVVLYNNADGMYEVSFYSNAVVSYDGS 142
Query: 448 VSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDKRIYSMFE---SGA 618
+ W+ + +++ ++P D Q CT KF S ++ E+D V+ + S+ + SG
Sbjct: 143 IFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRSWTYDRTEIDLVLKSEVASLDDFTPSGE 202
Query: 619 WDVTAL 636
WD+ AL
Sbjct: 203 WDIVAL 208
>BC075040-1|AAH75040.1| 502|Homo sapiens cholinergic receptor,
nicotinic, beta 2 (neuronal) protein.
Length = 502
Score = 69.7 bits (163), Expect = 1e-11
Identities = 40/126 (31%), Positives = 64/126 (50%), Gaps = 5/126 (3%)
Frame = +1
Query: 274 MLQNWIDKRLSWNAGEW-GCSTWLVSSERLWGPDVVLLNAA-ATTAGDYALRARVSNNGS 447
+ Q W D RL+W E+ + S+ +W PDVVL N A + A VS +GS
Sbjct: 83 LTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLPDVVLYNNADGMYEVSFYSNAVVSYDGS 142
Query: 448 VSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDKRIYSMFE---SGA 618
+ W+ + +++ ++P D Q CT KF S ++ E+D V+ + S+ + SG
Sbjct: 143 IFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRSWTYDRTEIDLVLKSEVASLDDFTPSGE 202
Query: 619 WDVTAL 636
WD+ AL
Sbjct: 203 WDIVAL 208
>AL592078-3|CAI16184.1| 502|Homo sapiens cholinergic receptor,
nicotinic, beta 2 (neuronal) protein.
Length = 502
Score = 69.7 bits (163), Expect = 1e-11
Identities = 40/126 (31%), Positives = 64/126 (50%), Gaps = 5/126 (3%)
Frame = +1
Query: 274 MLQNWIDKRLSWNAGEW-GCSTWLVSSERLWGPDVVLLNAA-ATTAGDYALRARVSNNGS 447
+ Q W D RL+W E+ + S+ +W PDVVL N A + A VS +GS
Sbjct: 83 LTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLPDVVLYNNADGMYEVSFYSNAVVSYDGS 142
Query: 448 VSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDKRIYSMFE---SGA 618
+ W+ + +++ ++P D Q CT KF S ++ E+D V+ + S+ + SG
Sbjct: 143 IFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRSWTYDRTEIDLVLKSEVASLDDFTPSGE 202
Query: 619 WDVTAL 636
WD+ AL
Sbjct: 203 WDIVAL 208
>AF077186-1|AAD45422.1| 502|Homo sapiens neuronal nicotinic
acetylcholine receptor beta 2 protein.
Length = 502
Score = 69.7 bits (163), Expect = 1e-11
Identities = 40/126 (31%), Positives = 64/126 (50%), Gaps = 5/126 (3%)
Frame = +1
Query: 274 MLQNWIDKRLSWNAGEW-GCSTWLVSSERLWGPDVVLLNAA-ATTAGDYALRARVSNNGS 447
+ Q W D RL+W E+ + S+ +W PDVVL N A + A VS +GS
Sbjct: 83 LTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLPDVVLYNNADGMYEVSFYSNAVVSYDGS 142
Query: 448 VSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDKRIYSMFE---SGA 618
+ W+ + +++ ++P D Q CT KF S ++ E+D V+ + S+ + SG
Sbjct: 143 IFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRSWTYDRTEIDLVLKSEVASLDDFTPSGE 202
Query: 619 WDVTAL 636
WD+ AL
Sbjct: 203 WDIVAL 208
>Y08421-1|CAA69698.1| 627|Homo sapiens nicotinic acetylcholine
receptor alpha4 subunit precursor protein.
Length = 627
Score = 67.3 bits (157), Expect = 7e-11
Identities = 55/198 (27%), Positives = 98/198 (49%), Gaps = 12/198 (6%)
Frame = +1
Query: 64 LLPFLLTCAIASAAECEN-ATSLSLMIDSLLATYDRDSPPDSKI--VVNLTLHLRHANIR 234
LL L T + +++ E A + ++ L + Y++ S P + I VV + L A +
Sbjct: 15 LLLLLGTGLLRASSHVETRAHAEERLLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLI 74
Query: 235 E-SESTVRIQADLQMLQNWIDKRLSWNAGEWGCSTWL-VSSERLWGPDVVLLNAAATTAG 408
+ E + ++ + Q W D +L W+ ++ T + + SE +W PD+VL N A G
Sbjct: 75 DVDEKNQMMTTNVWVKQEWHDYKLRWDPADYENVTSIRIPSELIWRPDIVLYNNAD---G 131
Query: 409 DYAL----RARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDF 576
D+A+ +A + ++G V W + S+ + +P D Q CT KFGS ++ ++D
Sbjct: 132 DFAVTHLTKAHLFHDGRVQWTPPAIYKSSCSIDVTFFPFDQQNCTMKFGSWTYDKAKIDL 191
Query: 577 V-IDKRI--YSMFESGAW 621
V + R+ +ESG W
Sbjct: 192 VNMHSRVDQLDFWESGEW 209
>X89741-1|CAA61893.1| 627|Homo sapiens neuronal acetylcholine
receptor alpha-4 subunit protein.
Length = 627
Score = 67.3 bits (157), Expect = 7e-11
Identities = 55/198 (27%), Positives = 98/198 (49%), Gaps = 12/198 (6%)
Frame = +1
Query: 64 LLPFLLTCAIASAAECEN-ATSLSLMIDSLLATYDRDSPPDSKI--VVNLTLHLRHANIR 234
LL L T + +++ E A + ++ L + Y++ S P + I VV + L A +
Sbjct: 15 LLLLLGTGLLRASSHVETRAHAEERLLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLI 74
Query: 235 E-SESTVRIQADLQMLQNWIDKRLSWNAGEWGCSTWL-VSSERLWGPDVVLLNAAATTAG 408
+ E + ++ + Q W D +L W+ ++ T + + SE +W PD+VL N A G
Sbjct: 75 DVDEKNQMMTTNVWVKQEWHDYKLRWDPADYENVTSIRIPSELIWRPDIVLYNNAD---G 131
Query: 409 DYAL----RARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDF 576
D+A+ +A + ++G V W + S+ + +P D Q CT KFGS ++ ++D
Sbjct: 132 DFAVTHLTKAHLFHDGRVQWTPPAIYKSSCSIDVTFFPFDQQNCTMKFGSWTYDKAKIDL 191
Query: 577 V-IDKRI--YSMFESGAW 621
V + R+ +ESG W
Sbjct: 192 VNMHSRVDQLDFWESGEW 209
>U62433-1|AAB40111.1| 627|Homo sapiens nicotinic acetylcholine
receptor alpha4 subunit precursor protein.
Length = 627
Score = 67.3 bits (157), Expect = 7e-11
Identities = 55/198 (27%), Positives = 98/198 (49%), Gaps = 12/198 (6%)
Frame = +1
Query: 64 LLPFLLTCAIASAAECEN-ATSLSLMIDSLLATYDRDSPPDSKI--VVNLTLHLRHANIR 234
LL L T + +++ E A + ++ L + Y++ S P + I VV + L A +
Sbjct: 15 LLLLLGTGLLRASSHVETRAHAEERLLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLI 74
Query: 235 E-SESTVRIQADLQMLQNWIDKRLSWNAGEWGCSTWL-VSSERLWGPDVVLLNAAATTAG 408
+ E + ++ + Q W D +L W+ ++ T + + SE +W PD+VL N A G
Sbjct: 75 DVDEKNQMMTTNVWVKQEWHDYKLRWDPADYENVTSIRIPSELIWRPDIVLYNNAD---G 131
Query: 409 DYAL----RARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDF 576
D+A+ +A + ++G V W + S+ + +P D Q CT KFGS ++ ++D
Sbjct: 132 DFAVTHLTKAHLFHDGRVQWTPPAIYKSSCSIDVTFFPFDQQNCTMKFGSWTYDKAKIDL 191
Query: 577 V-IDKRI--YSMFESGAW 621
V + R+ +ESG W
Sbjct: 192 VNMHSRVDQLDFWESGEW 209
>L35901-1|AAA64743.1| 627|Homo sapiens nicotinic acetylcholine
receptor alpha 4 subunit protein.
Length = 627
Score = 67.3 bits (157), Expect = 7e-11
Identities = 55/198 (27%), Positives = 98/198 (49%), Gaps = 12/198 (6%)
Frame = +1
Query: 64 LLPFLLTCAIASAAECEN-ATSLSLMIDSLLATYDRDSPPDSKI--VVNLTLHLRHANIR 234
LL L T + +++ E A + ++ L + Y++ S P + I VV + L A +
Sbjct: 15 LLLLLGTGLLRASSHVETRAHAEERLLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLI 74
Query: 235 E-SESTVRIQADLQMLQNWIDKRLSWNAGEWGCSTWL-VSSERLWGPDVVLLNAAATTAG 408
+ E + ++ + Q W D +L W+ ++ T + + SE +W PD+VL N A G
Sbjct: 75 DVDEKNQMMTTNVWVKQEWHDYKLRWDPADYENVTSIRIPSELIWRPDIVLYNNAD---G 131
Query: 409 DYAL----RARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDF 576
D+A+ +A + ++G V W + S+ + +P D Q CT KFGS ++ ++D
Sbjct: 132 DFAVTHLTKAHLFHDGRVQWTPPAIYKSSCSIDVTFFPFDQQNCTMKFGSWTYDKAKIDL 191
Query: 577 V-IDKRI--YSMFESGAW 621
V + R+ +ESG W
Sbjct: 192 VNMHSRVDQLDFWESGEW 209
>DQ093071-1|AAY88737.1| 627|Homo sapiens cholinergic receptor,
nicotinic, alpha polypeptide 4 protein.
Length = 627
Score = 67.3 bits (157), Expect = 7e-11
Identities = 55/198 (27%), Positives = 98/198 (49%), Gaps = 12/198 (6%)
Frame = +1
Query: 64 LLPFLLTCAIASAAECEN-ATSLSLMIDSLLATYDRDSPPDSKI--VVNLTLHLRHANIR 234
LL L T + +++ E A + ++ L + Y++ S P + I VV + L A +
Sbjct: 15 LLLLLGTGLLRASSHVETRAHAEERLLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLI 74
Query: 235 E-SESTVRIQADLQMLQNWIDKRLSWNAGEWGCSTWL-VSSERLWGPDVVLLNAAATTAG 408
+ E + ++ + Q W D +L W+ ++ T + + SE +W PD+VL N A G
Sbjct: 75 DVDEKNQMMTTNVWVKQEWHDYKLRWDPADYENVTSIRIPSELIWRPDIVLYNNAD---G 131
Query: 409 DYAL----RARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDF 576
D+A+ +A + ++G V W + S+ + +P D Q CT KFGS ++ ++D
Sbjct: 132 DFAVTHLTKAHLFHDGRVQWTPPAIYKSSCSIDVTFFPFDQQNCTMKFGSWTYDKAKIDL 191
Query: 577 V-IDKRI--YSMFESGAW 621
V + R+ +ESG W
Sbjct: 192 VNMHSRVDQLDFWESGEW 209
>BC096290-1|AAH96290.1| 627|Homo sapiens cholinergic receptor,
nicotinic, alpha 4 protein.
Length = 627
Score = 67.3 bits (157), Expect = 7e-11
Identities = 55/198 (27%), Positives = 98/198 (49%), Gaps = 12/198 (6%)
Frame = +1
Query: 64 LLPFLLTCAIASAAECEN-ATSLSLMIDSLLATYDRDSPPDSKI--VVNLTLHLRHANIR 234
LL L T + +++ E A + ++ L + Y++ S P + I VV + L A +
Sbjct: 15 LLLLLGTGLLRASSHVETRAHAEERLLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLI 74
Query: 235 E-SESTVRIQADLQMLQNWIDKRLSWNAGEWGCSTWL-VSSERLWGPDVVLLNAAATTAG 408
+ E + ++ + Q W D +L W+ ++ T + + SE +W PD+VL N A G
Sbjct: 75 DVDEKNQMMTTNVWVKQEWHDYKLRWDPADYENVTSIRIPSELIWRPDIVLYNNAD---G 131
Query: 409 DYAL----RARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDF 576
D+A+ +A + ++G V W + S+ + +P D Q CT KFGS ++ ++D
Sbjct: 132 DFAVTHLTKAHLFHDGRVQWTPPAIYKSSCSIDVTFFPFDQQNCTMKFGSWTYDKAKIDL 191
Query: 577 V-IDKRI--YSMFESGAW 621
V + R+ +ESG W
Sbjct: 192 VNMHSRVDQLDFWESGEW 209
>X87629-1|CAA60959.1| 602|Homo sapiens nicotinic acetylcholine
receptor protein.
Length = 602
Score = 66.9 bits (156), Expect = 9e-11
Identities = 49/173 (28%), Positives = 87/173 (50%), Gaps = 11/173 (6%)
Frame = +1
Query: 136 MIDSLLATYDRDSPPDSKI--VVNLTLHLRHANIRE-SESTVRIQADLQMLQNWIDKRLS 306
++ L + Y++ S P + I VV + L A + + E + ++ + Q W D +L
Sbjct: 15 LLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLR 74
Query: 307 WNAGEWGCSTWL-VSSERLWGPDVVLLNAAATTAGDYAL----RARVSNNGSVSWIKRLD 471
W+ ++ T + + SE +W PD+VL N A GD+A+ +A + ++G V W
Sbjct: 75 WDPADYENVTSIRIPSELIWRPDIVLYNNAD---GDFAVTHLTKAHLFHDGRVQWTPPAI 131
Query: 472 ISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFV-IDKRI--YSMFESGAW 621
+ S+ + +P D Q CT KFGS ++ ++D V + R+ +ESG W
Sbjct: 132 YKSSCSIDVTFFPFDQQNCTMKFGSWTYDKAKIDLVNMHSRVDQLDFWESGEW 184
>Y16282-1|CAA76155.1| 494|Homo sapiens nicotinic acetylcholine
receptor alpha6 subunit precursor protein.
Length = 494
Score = 64.1 bits (149), Expect = 6e-10
Identities = 44/184 (23%), Positives = 86/184 (46%), Gaps = 11/184 (5%)
Frame = +1
Query: 109 CENATSLSLMIDSLLATYDRDSPPDSKIVVNLTLHLRHANIRES---ESTVRIQADLQML 279
C + + L + Y++ P + +T+H A + + E ++ +L +
Sbjct: 28 CVGCATEERLFHKLFSHYNQFIRPVENVSDPVTVHFEVAITQLANVDEVNQIMETNLWLR 87
Query: 280 QNWIDKRLSWNAGEW-GCSTWLVSSERLWGPDVVLLNAAATTAGDYAL----RARVSNNG 444
W D +L W+ E+ G T V ++++W PD+VL N A GD+ + +A + NG
Sbjct: 88 HIWNDYKLRWDPMEYDGIETLRVPADKIWKPDIVLYNNAV---GDFQVEGKTKALLKYNG 144
Query: 445 SVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD-FVIDKRI--YSMFESG 615
++W + M + +P D Q C+ KFGS ++ E+D +I ++ +E+
Sbjct: 145 MITWTPPAIFKSSCPMDITFFPFDHQNCSLKFGSWTYDKAEIDLLIIGSKVDMNDFWENS 204
Query: 616 AWDV 627
W++
Sbjct: 205 EWEI 208
>U62435-1|AAB40113.1| 494|Homo sapiens nicotinic acetylcholine
receptor alpha6 subunit precursor protein.
Length = 494
Score = 64.1 bits (149), Expect = 6e-10
Identities = 44/184 (23%), Positives = 86/184 (46%), Gaps = 11/184 (5%)
Frame = +1
Query: 109 CENATSLSLMIDSLLATYDRDSPPDSKIVVNLTLHLRHANIRES---ESTVRIQADLQML 279
C + + L + Y++ P + +T+H A + + E ++ +L +
Sbjct: 28 CVGCATEERLFHKLFSHYNQFIRPVENVSDPVTVHFEVAITQLANVDEVNQIMETNLWLR 87
Query: 280 QNWIDKRLSWNAGEW-GCSTWLVSSERLWGPDVVLLNAAATTAGDYAL----RARVSNNG 444
W D +L W+ E+ G T V ++++W PD+VL N A GD+ + +A + NG
Sbjct: 88 HIWNDYKLRWDPMEYDGIETLRVPADKIWKPDIVLYNNAV---GDFQVEGKTKALLKYNG 144
Query: 445 SVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD-FVIDKRI--YSMFESG 615
++W + M + +P D Q C+ KFGS ++ E+D +I ++ +E+
Sbjct: 145 MITWTPPAIFKSSCPMDITFFPFDHQNCSLKFGSWTYDKAEIDLLIIGSKVDMNDFWENS 204
Query: 616 AWDV 627
W++
Sbjct: 205 EWEI 208
>BC014456-1|AAH14456.1| 494|Homo sapiens cholinergic receptor,
nicotinic, alpha 6 protein.
Length = 494
Score = 64.1 bits (149), Expect = 6e-10
Identities = 44/184 (23%), Positives = 86/184 (46%), Gaps = 11/184 (5%)
Frame = +1
Query: 109 CENATSLSLMIDSLLATYDRDSPPDSKIVVNLTLHLRHANIRES---ESTVRIQADLQML 279
C + + L + Y++ P + +T+H A + + E ++ +L +
Sbjct: 28 CVGCATEERLFHKLFSHYNQFIRPVENVSDPVTVHFEVAITQLANVDEVNQIMETNLWLR 87
Query: 280 QNWIDKRLSWNAGEW-GCSTWLVSSERLWGPDVVLLNAAATTAGDYAL----RARVSNNG 444
W D +L W+ E+ G T V ++++W PD+VL N A GD+ + +A + NG
Sbjct: 88 HIWNDYKLRWDPMEYDGIETLRVPADKIWKPDIVLYNNAV---GDFQVEGKTKALLKYNG 144
Query: 445 SVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD-FVIDKRI--YSMFESG 615
++W + M + +P D Q C+ KFGS ++ E+D +I ++ +E+
Sbjct: 145 MITWTPPAIFKSSCPMDITFFPFDHQNCSLKFGSWTYDKAEIDLLIIGSKVDMNDFWENS 204
Query: 616 AWDV 627
W++
Sbjct: 205 EWEI 208
>AB079251-1|BAC06855.1| 494|Homo sapiens Nicotinic acetylcholine
receptor alpha 6 protein.
Length = 494
Score = 64.1 bits (149), Expect = 6e-10
Identities = 44/184 (23%), Positives = 86/184 (46%), Gaps = 11/184 (5%)
Frame = +1
Query: 109 CENATSLSLMIDSLLATYDRDSPPDSKIVVNLTLHLRHANIRES---ESTVRIQADLQML 279
C + + L + Y++ P + +T+H A + + E ++ +L +
Sbjct: 28 CVGCATEERLFHKLFSHYNQFIRPVENVSDPVTVHFEVAITQLANVDEVNQIMETNLWLR 87
Query: 280 QNWIDKRLSWNAGEW-GCSTWLVSSERLWGPDVVLLNAAATTAGDYAL----RARVSNNG 444
W D +L W+ E+ G T V ++++W PD+VL N A GD+ + +A + NG
Sbjct: 88 HIWNDYKLRWDPMEYDGIETLRVPADKIWKPDIVLYNNAV---GDFQVEGKTKALLKYNG 144
Query: 445 SVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD-FVIDKRI--YSMFESG 615
++W + M + +P D Q C+ KFGS ++ E+D +I ++ +E+
Sbjct: 145 MITWTPPAIFKSSCPMDITFFPFDHQNCSLKFGSWTYDKAEIDLLIIGSKVDMNDFWENS 204
Query: 616 AWDV 627
W++
Sbjct: 205 EWEI 208
>X14830-1|CAA32939.1| 501|Homo sapiens protein ( Human mRNA for
muscle acetylcholine receptor beta-subunit. ).
Length = 501
Score = 62.1 bits (144), Expect = 3e-09
Identities = 45/132 (34%), Positives = 68/132 (51%), Gaps = 4/132 (3%)
Frame = +1
Query: 187 KIVVNLTL-HLRHANIRESESTVRIQADLQMLQNWIDKRLSWNAGEW-GCSTWLVSSERL 360
++ V L L L N ++ E + ++ DL+ W D RLSW+ E G + +++E +
Sbjct: 53 RVSVGLILAQLISLNEKDEEMSTKVYLDLE----WTDYRLSWDPAEHDGIDSLRITAESV 108
Query: 361 WGPDVVLLNAAATTAGDYAL--RARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTF 534
W PDVVLLN D AL VS++GSV W + S+Q+ +P D Q CT
Sbjct: 109 WLPDVVLLNNNDGNF-DVALDISVVVSSDGSVRWQPPGIYRSSCSIQVTYFPFDWQNCTM 167
Query: 535 KFGSRMHNSDEM 570
F S ++S E+
Sbjct: 168 VFSSYSYDSSEV 179
>BC011371-1|AAH11371.1| 501|Homo sapiens cholinergic receptor,
nicotinic, beta 1 (muscle) protein.
Length = 501
Score = 62.1 bits (144), Expect = 3e-09
Identities = 45/132 (34%), Positives = 68/132 (51%), Gaps = 4/132 (3%)
Frame = +1
Query: 187 KIVVNLTL-HLRHANIRESESTVRIQADLQMLQNWIDKRLSWNAGEW-GCSTWLVSSERL 360
++ V L L L N ++ E + ++ DL+ W D RLSW+ E G + +++E +
Sbjct: 53 RVSVGLILAQLISLNEKDEEMSTKVYLDLE----WTDYRLSWDPAEHDGIDSLRITAESV 108
Query: 361 WGPDVVLLNAAATTAGDYAL--RARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTF 534
W PDVVLLN D AL VS++GSV W + S+Q+ +P D Q CT
Sbjct: 109 WLPDVVLLNNNDGNF-DVALDISVVVSSDGSVRWQPPGIYRSSCSIQVTYFPFDWQNCTM 167
Query: 535 KFGSRMHNSDEM 570
F S ++S E+
Sbjct: 168 VFSSYSYDSSEV 179
>BC023553-1|AAH23553.1| 501|Homo sapiens cholinergic receptor,
nicotinic, beta 1 (muscle) protein.
Length = 501
Score = 60.9 bits (141), Expect = 6e-09
Identities = 43/134 (32%), Positives = 69/134 (51%), Gaps = 6/134 (4%)
Frame = +1
Query: 187 KIVVNLTL-HLRHANIRESESTVRIQADLQMLQNWIDKRLSWNAGEW-GCSTWLVSSERL 360
++ V L L L N ++ E + ++ DL+ W D RLSW+ E G + +++E +
Sbjct: 53 RVSVGLILAQLISLNEKDEEMSTKVYLDLE----WTDYRLSWDPAEHDGIDSLRITAESV 108
Query: 361 WGPDVVLLNAAATTAGDY----ALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTC 528
W PDVVLLN G++ + VS++GSV W + S+Q+ +P D Q C
Sbjct: 109 WLPDVVLLN---NNDGNFYVALDISVVVSSDGSVRWQPPGIYRSSCSIQVTYFPFDWQNC 165
Query: 529 TFKFGSRMHNSDEM 570
T F S ++S E+
Sbjct: 166 TMVFSSYSYDSSEV 179
>Y00762-1|CAA68731.1| 457|Homo sapiens protein ( Human mRNA for
muscle acetylcholine receptor alpha-subunit. ).
Length = 457
Score = 60.5 bits (140), Expect = 8e-09
Identities = 49/195 (25%), Positives = 90/195 (46%), Gaps = 11/195 (5%)
Frame = +1
Query: 70 PFLLTCAIASAAECENATSLSLMIDSLLATYDRDSPP--DSKIVVNLTLHLRHAN-IRES 240
P LL ++ SA + + ++ L Y P D + VV +T+ L+ I
Sbjct: 5 PLLLLFSLCSAGLVLGSEHETRLVAKLFKDYSSVVRPVEDHRQVVEVTVGLQLIQLINVD 64
Query: 241 ESTVRIQADLQMLQNWIDKRLSWNAGEWGCSTWL-VSSERLWGPDVVLLNAAATTAGDYA 417
E + ++++ Q W+D L WN ++G + + SE++W PD+VL N A GD+A
Sbjct: 65 EVNQIVTTNVRLKQQWVDYNLKWNPDDYGGVKKIHIPSEKIWRPDLVLYNNA---DGDFA 121
Query: 418 L----RARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSD--EMDFV 579
+ + + G ++W + + + ++P D Q C+ K G+ ++ ++
Sbjct: 122 IVKFTKVLLQYTGHITWTPPAIFKSYCEIIVTHFPFDEQNCSMKLGTWTYDGSVVAINPE 181
Query: 580 IDKRIYSMF-ESGAW 621
D+ S F ESG W
Sbjct: 182 SDQPDLSNFMESGEW 196
>X02502-1|CAA26344.1| 457|Homo sapiens acetylcholine receptor
protein.
Length = 457
Score = 60.5 bits (140), Expect = 8e-09
Identities = 49/195 (25%), Positives = 90/195 (46%), Gaps = 11/195 (5%)
Frame = +1
Query: 70 PFLLTCAIASAAECENATSLSLMIDSLLATYDRDSPP--DSKIVVNLTLHLRHAN-IRES 240
P LL ++ SA + + ++ L Y P D + VV +T+ L+ I
Sbjct: 5 PLLLLFSLCSAGLVLGSEHETRLVAKLFKDYSSVVRPVEDHRQVVEVTVGLQLIQLINVD 64
Query: 241 ESTVRIQADLQMLQNWIDKRLSWNAGEWGCSTWL-VSSERLWGPDVVLLNAAATTAGDYA 417
E + ++++ Q W+D L WN ++G + + SE++W PD+VL N A GD+A
Sbjct: 65 EVNQIVTTNVRLKQQWVDYNLKWNPDDYGGVKKIHIPSEKIWRPDLVLYNNA---DGDFA 121
Query: 418 L----RARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSD--EMDFV 579
+ + + G ++W + + + ++P D Q C+ K G+ ++ ++
Sbjct: 122 IVKFTKVLLQYTGHITWTPPAIFKSYCEIIVTHFPFDEQNCSMKLGTWTYDGSVVAINPE 181
Query: 580 IDKRIYSMF-ESGAW 621
D+ S F ESG W
Sbjct: 182 SDQPDLSNFMESGEW 196
>S77094-1|AAD14247.1| 457|Homo sapiens nicotinic acetylcholine
receptor alpha subunit|AChR protein.
Length = 457
Score = 60.5 bits (140), Expect = 8e-09
Identities = 49/195 (25%), Positives = 90/195 (46%), Gaps = 11/195 (5%)
Frame = +1
Query: 70 PFLLTCAIASAAECENATSLSLMIDSLLATYDRDSPP--DSKIVVNLTLHLRHAN-IRES 240
P LL ++ SA + + ++ L Y P D + VV +T+ L+ I
Sbjct: 5 PLLLLFSLCSAGLVLGSEHETRLVAKLFKDYSSVVRPVEDHRQVVEVTVGLQLIQLINVD 64
Query: 241 ESTVRIQADLQMLQNWIDKRLSWNAGEWGCSTWL-VSSERLWGPDVVLLNAAATTAGDYA 417
E + ++++ Q W+D L WN ++G + + SE++W PD+VL N A GD+A
Sbjct: 65 EVNQIVTTNVRLKQQWVDYNLKWNPDDYGGVKKIHIPSEKIWRPDLVLYNNA---DGDFA 121
Query: 418 L----RARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSD--EMDFV 579
+ + + G ++W + + + ++P D Q C+ K G+ ++ ++
Sbjct: 122 IVKFTKVLLQYTGHITWTPPAIFKSYCEIIVTHFPFDEQNCSMKLGTWTYDGSVVAINPE 181
Query: 580 IDKRIYSMF-ESGAW 621
D+ S F ESG W
Sbjct: 182 SDQPDLSNFMESGEW 196
>BC006314-1|AAH06314.1| 269|Homo sapiens CHRNA1 protein protein.
Length = 269
Score = 60.5 bits (140), Expect = 8e-09
Identities = 49/195 (25%), Positives = 90/195 (46%), Gaps = 11/195 (5%)
Frame = +1
Query: 70 PFLLTCAIASAAECENATSLSLMIDSLLATYDRDSPP--DSKIVVNLTLHLRHAN-IRES 240
P LL ++ SA + + ++ L Y P D + VV +T+ L+ I
Sbjct: 5 PLLLLFSLCSAGLVLGSEHETRLVAKLFKDYSSVVRPVEDHRQVVEVTVGLQLIQLINVD 64
Query: 241 ESTVRIQADLQMLQNWIDKRLSWNAGEWGCSTWL-VSSERLWGPDVVLLNAAATTAGDYA 417
E + ++++ Q W+D L WN ++G + + SE++W PD+VL N A GD+A
Sbjct: 65 EVNQIVTTNVRLKQQWVDYNLKWNPDDYGGVKKIHIPSEKIWRPDLVLYNNA---DGDFA 121
Query: 418 L----RARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSD--EMDFV 579
+ + + G ++W + + + ++P D Q C+ K G+ ++ ++
Sbjct: 122 IVKFTKVLLQYTGHITWTPPAIFKSYCEIIVTHFPFDEQNCSMKLGTWTYDGSVVAINPE 181
Query: 580 IDKRIYSMF-ESGAW 621
D+ S F ESG W
Sbjct: 182 SDQPDLSNFMESGEW 196
>AC018890-1|AAY14687.1| 457|Homo sapiens unknown protein.
Length = 457
Score = 60.5 bits (140), Expect = 8e-09
Identities = 49/195 (25%), Positives = 90/195 (46%), Gaps = 11/195 (5%)
Frame = +1
Query: 70 PFLLTCAIASAAECENATSLSLMIDSLLATYDRDSPP--DSKIVVNLTLHLRHAN-IRES 240
P LL ++ SA + + ++ L Y P D + VV +T+ L+ I
Sbjct: 5 PLLLLFSLCSAGLVLGSEHETRLVAKLFKDYSSVVRPVEDHRQVVEVTVGLQLIQLINVD 64
Query: 241 ESTVRIQADLQMLQNWIDKRLSWNAGEWGCSTWL-VSSERLWGPDVVLLNAAATTAGDYA 417
E + ++++ Q W+D L WN ++G + + SE++W PD+VL N A GD+A
Sbjct: 65 EVNQIVTTNVRLKQQWVDYNLKWNPDDYGGVKKIHIPSEKIWRPDLVLYNNA---DGDFA 121
Query: 418 L----RARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSD--EMDFV 579
+ + + G ++W + + + ++P D Q C+ K G+ ++ ++
Sbjct: 122 IVKFTKVLLQYTGHITWTPPAIFKSYCEIIVTHFPFDEQNCSMKLGTWTYDGSVVAINPE 181
Query: 580 IDKRIYSMF-ESGAW 621
D+ S F ESG W
Sbjct: 182 SDQPDLSNFMESGEW 196
>BC113575-1|AAI13576.1| 479|Homo sapiens cholinergic receptor,
nicotinic, alpha 9 protein.
Length = 479
Score = 59.3 bits (137), Expect = 2e-08
Identities = 46/184 (25%), Positives = 84/184 (45%), Gaps = 8/184 (4%)
Frame = +1
Query: 100 AAECENATSLSLMIDSLLATYDRDSPP--DSKIVVNLTLHLRHANIRESESTVRI-QADL 270
AAE + + + L Y P D+ V+N+TL + + I++ + +I A L
Sbjct: 22 AAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQITLSQIKDMDERNQILTAYL 81
Query: 271 QMLQNWIDKRLSWNAGEW-GCSTWLVSSERLWGPDVVLLNAAATTAGDYA-LRARVSNNG 444
+ Q W D L+W+ ++ G + + S+ +W PD+VL N A + + + +G
Sbjct: 82 WIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKADDESSEPVNTNVVLRYDG 141
Query: 445 SVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDF--VIDKRIYSMF-ESG 615
++W + + + +P D Q C FGS +N +++D +D S F E
Sbjct: 142 LITWDAPAITKSSCVVDVTYFPFDNQQCNLTFGSWTYNGNQVDIFNALDSGDLSDFIEDV 201
Query: 616 AWDV 627
W+V
Sbjct: 202 EWEV 205
>BC113549-1|AAI13550.1| 479|Homo sapiens cholinergic receptor,
nicotinic, alpha 9 protein.
Length = 479
Score = 59.3 bits (137), Expect = 2e-08
Identities = 46/184 (25%), Positives = 84/184 (45%), Gaps = 8/184 (4%)
Frame = +1
Query: 100 AAECENATSLSLMIDSLLATYDRDSPP--DSKIVVNLTLHLRHANIRESESTVRI-QADL 270
AAE + + + L Y P D+ V+N+TL + + I++ + +I A L
Sbjct: 22 AAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQITLSQIKDMDERNQILTAYL 81
Query: 271 QMLQNWIDKRLSWNAGEW-GCSTWLVSSERLWGPDVVLLNAAATTAGDYA-LRARVSNNG 444
+ Q W D L+W+ ++ G + + S+ +W PD+VL N A + + + +G
Sbjct: 82 WIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKADDESSEPVNTNVVLRYDG 141
Query: 445 SVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDF--VIDKRIYSMF-ESG 615
++W + + + +P D Q C FGS +N +++D +D S F E
Sbjct: 142 LITWDAPAITKSSCVVDVTYFPFDNQQCNLTFGSWTYNGNQVDIFNALDSGDLSDFIEDV 201
Query: 616 AWDV 627
W+V
Sbjct: 202 EWEV 205
>AY123244-1|AAM74523.1| 479|Homo sapiens nicotinic acetylcholine
receptor subunit alpha 9 protein.
Length = 479
Score = 59.3 bits (137), Expect = 2e-08
Identities = 46/184 (25%), Positives = 84/184 (45%), Gaps = 8/184 (4%)
Frame = +1
Query: 100 AAECENATSLSLMIDSLLATYDRDSPP--DSKIVVNLTLHLRHANIRESESTVRI-QADL 270
AAE + + + L Y P D+ V+N+TL + + I++ + +I A L
Sbjct: 22 AAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQITLSQIKDMDERNQILTAYL 81
Query: 271 QMLQNWIDKRLSWNAGEW-GCSTWLVSSERLWGPDVVLLNAAATTAGDYA-LRARVSNNG 444
+ Q W D L+W+ ++ G + + S+ +W PD+VL N A + + + +G
Sbjct: 82 WIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKADDESSEPVNTNVVLRYDG 141
Query: 445 SVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDF--VIDKRIYSMF-ESG 615
++W + + + +P D Q C FGS +N +++D +D S F E
Sbjct: 142 LITWDAPAITKSSCVVDVTYFPFDNQQCNLTFGSWTYNGNQVDIFNALDSGDLSDFIEDV 201
Query: 616 AWDV 627
W+V
Sbjct: 202 EWEV 205
>AJ243342-1|CAB65091.1| 479|Homo sapiens nicotinic acetylcholine
receptor alpha 9 subunit protein.
Length = 479
Score = 59.3 bits (137), Expect = 2e-08
Identities = 46/184 (25%), Positives = 84/184 (45%), Gaps = 8/184 (4%)
Frame = +1
Query: 100 AAECENATSLSLMIDSLLATYDRDSPP--DSKIVVNLTLHLRHANIRESESTVRI-QADL 270
AAE + + + L Y P D+ V+N+TL + + I++ + +I A L
Sbjct: 22 AAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQITLSQIKDMDERNQILTAYL 81
Query: 271 QMLQNWIDKRLSWNAGEW-GCSTWLVSSERLWGPDVVLLNAAATTAGDYA-LRARVSNNG 444
+ Q W D L+W+ ++ G + + S+ +W PD+VL N A + + + +G
Sbjct: 82 WIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKADDESSEPVNTNVVLRYDG 141
Query: 445 SVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDF--VIDKRIYSMF-ESG 615
++W + + + +P D Q C FGS +N +++D +D S F E
Sbjct: 142 LITWDAPAITKSSCVVDVTYFPFDNQQCNLTFGSWTYNGNQVDIFNALDSGDLSDFIEDV 201
Query: 616 AWDV 627
W+V
Sbjct: 202 EWEV 205
>AF227732-1|AAF61920.1| 470|Homo sapiens nicotinic acetylcholine
receptor alpha 9 subunit protein.
Length = 470
Score = 59.3 bits (137), Expect = 2e-08
Identities = 46/184 (25%), Positives = 84/184 (45%), Gaps = 8/184 (4%)
Frame = +1
Query: 100 AAECENATSLSLMIDSLLATYDRDSPP--DSKIVVNLTLHLRHANIRESESTVRI-QADL 270
AAE + + + L Y P D+ V+N+TL + + I++ + +I A L
Sbjct: 16 AAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQITLSQIKDMDERNQILTAYL 75
Query: 271 QMLQNWIDKRLSWNAGEW-GCSTWLVSSERLWGPDVVLLNAAATTAGDYA-LRARVSNNG 444
+ Q W D L+W+ ++ G + + S+ +W PD+VL N A + + + +G
Sbjct: 76 WIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKADDESSEPVNTNVVLRYDG 135
Query: 445 SVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDF--VIDKRIYSMF-ESG 615
++W + + + +P D Q C FGS +N +++D +D S F E
Sbjct: 136 LITWDAPAITKSSCVVDVTYFPFDNQQCNLTFGSWTYNGNQVDIFNALDSGDLSDFIEDV 195
Query: 616 AWDV 627
W+V
Sbjct: 196 EWEV 199
>AC118275-1|AAY40986.1| 479|Homo sapiens unknown protein.
Length = 479
Score = 59.3 bits (137), Expect = 2e-08
Identities = 46/184 (25%), Positives = 84/184 (45%), Gaps = 8/184 (4%)
Frame = +1
Query: 100 AAECENATSLSLMIDSLLATYDRDSPP--DSKIVVNLTLHLRHANIRESESTVRI-QADL 270
AAE + + + L Y P D+ V+N+TL + + I++ + +I A L
Sbjct: 22 AAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQITLSQIKDMDERNQILTAYL 81
Query: 271 QMLQNWIDKRLSWNAGEW-GCSTWLVSSERLWGPDVVLLNAAATTAGDYA-LRARVSNNG 444
+ Q W D L+W+ ++ G + + S+ +W PD+VL N A + + + +G
Sbjct: 82 WIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKADDESSEPVNTNVVLRYDG 141
Query: 445 SVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDF--VIDKRIYSMF-ESG 615
++W + + + +P D Q C FGS +N +++D +D S F E
Sbjct: 142 LITWDAPAITKSSCVVDVTYFPFDNQQCNLTFGSWTYNGNQVDIFNALDSGDLSDFIEDV 201
Query: 616 AWDV 627
W+V
Sbjct: 202 EWEV 205
>BC131799-1|AAI31800.1| 447|Homo sapiens 5-hydroxytryptamine
(serotonin) receptor 3, family member C protein.
Length = 447
Score = 58.4 bits (135), Expect = 3e-08
Identities = 28/110 (25%), Positives = 57/110 (51%), Gaps = 1/110 (0%)
Frame = +1
Query: 286 WIDKRLSWNAGEW-GCSTWLVSSERLWGPDVVLLNAAATTAGDYALRARVSNNGSVSWIK 462
W + ++WN E G + V +E LW PD+ ++ + L A +S+ G + + K
Sbjct: 95 WDNPFINWNPKECVGINKLTVLAENLWLPDIFIVESMDVDQTPSGLTAYISSEGRIKYDK 154
Query: 463 RLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDKRIYSMFES 612
+ +++ ++ + +P D Q CTF F S ++ D M +DK ++ + ++
Sbjct: 155 PMRVTSICNLDIFYFPFDQQNCTFTFSSFLYTVDSMLLGMDKEVWEITDT 204
>X66403-1|CAA47030.1| 493|Homo sapiens acetylcholine receptor
epsilon subunit CHRNE protein.
Length = 493
Score = 58.0 bits (134), Expect = 4e-08
Identities = 36/136 (26%), Positives = 71/136 (52%), Gaps = 3/136 (2%)
Frame = +1
Query: 178 PDSKIVVNLTLHLRHA-NIRESESTVRIQADLQMLQNWIDKRLSWNAGEWG-CSTWLVSS 351
P+ + ++L + L + ++ E E T+ + + +W D RL+++ ++G T V S
Sbjct: 45 PEDTVTISLKVTLTNLISLNEKEETLTTSVWIGI--DWQDYRLNYSKDDFGGIETLRVPS 102
Query: 352 ERLWGPDVVLLNAAATTAG-DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTC 528
E +W P++VL N G Y V GSV+W+ + ++++ +P D Q C
Sbjct: 103 ELVWLPEIVLENNIDGQFGVAYDANVLVYEGGSVTWLPPAIYRSVCAVEVTYFPFDWQNC 162
Query: 529 TFKFGSRMHNSDEMDF 576
+ F S+ +N++E++F
Sbjct: 163 SLIFRSQTYNAEEVEF 178
>AF459285-1|AAL66182.1| 447|Homo sapiens 5-hydroxytryptamine
receptor 3 subunit C protein.
Length = 447
Score = 58.0 bits (134), Expect = 4e-08
Identities = 28/110 (25%), Positives = 56/110 (50%), Gaps = 1/110 (0%)
Frame = +1
Query: 286 WIDKRLSWNAGEW-GCSTWLVSSERLWGPDVVLLNAAATTAGDYALRARVSNNGSVSWIK 462
W + ++WN E G + V +E LW PD+ ++ + L A +S+ G + + K
Sbjct: 95 WDNPFINWNPKECVGINKLTVLAENLWLPDIFIVESMDVDQTPSGLTAYISSEGRIKYDK 154
Query: 463 RLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDKRIYSMFES 612
+ +++ + + +P D Q CTF F S ++ D M +DK ++ + ++
Sbjct: 155 PMRVTSICKLDIFYFPFDQQNCTFTFSSFLYTVDSMLLGMDKEVWEITDT 204
>AF105999-1|AAD24503.1| 493|Homo sapiens acetylcholine receptor
epsilon subunit protein.
Length = 493
Score = 58.0 bits (134), Expect = 4e-08
Identities = 36/136 (26%), Positives = 71/136 (52%), Gaps = 3/136 (2%)
Frame = +1
Query: 178 PDSKIVVNLTLHLRHA-NIRESESTVRIQADLQMLQNWIDKRLSWNAGEWG-CSTWLVSS 351
P+ + ++L + L + ++ E E T+ + + +W D RL+++ ++G T V S
Sbjct: 45 PEDTVTISLKVTLTNLISLNEKEETLTTSVWIGI--DWQDYRLNYSKDDFGGIETLRVPS 102
Query: 352 ERLWGPDVVLLNAAATTAG-DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTC 528
E +W P++VL N G Y V GSV+W+ + ++++ +P D Q C
Sbjct: 103 ELVWLPEIVLENNIDGQFGVAYDANVLVYEGGSVTWLPPAIYRSVCAVEVTYFPFDWQNC 162
Query: 529 TFKFGSRMHNSDEMDF 576
+ F S+ +N++E++F
Sbjct: 163 SLIFRSQTYNAEEVEF 178
>AJ295237-1|CAC16144.1| 450|Homo sapiens neuronal nicotinic
acetylcholine receptor subunit4 protein.
Length = 450
Score = 57.2 bits (132), Expect = 7e-08
Identities = 48/176 (27%), Positives = 76/176 (43%), Gaps = 5/176 (2%)
Frame = +1
Query: 61 ILLPFLLTCAIASAAECENATSLSLMIDSLLATYDRDSPP--DSKIVVNLTLHLRHANIR 234
+LL FLL A E +L L D L A Y P D+ +N+TL + + I
Sbjct: 12 LLLLFLLPAECLGA---EGRLALKLFRD-LFANYTSALRPVADTDQTLNVTLEVTLSQII 67
Query: 235 ESESTVRIQA-DLQMLQNWIDKRLSWNAGEWG-CSTWLVSSERLWGPDVVLLNAA-ATTA 405
+ + ++ L + Q W D L W+ +G + S +W PD+VL N A A
Sbjct: 68 DMDERNQVLTLYLWIRQEWTDAYLRWDPNAYGGLDAIRIPSSLVWRPDIVLYNKADAQPP 127
Query: 406 GDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 573
G + + ++G+V W + + + +P D Q C FGS H ++D
Sbjct: 128 GSASTNVVLRHDGAVRWDAPAITRSSCRVDVAAFPFDAQHCGLTFGSWTHGGHQLD 183
>AJ278118-1|CAC20435.1| 450|Homo sapiens neuronal nicotinic
acetylcholine alpha10 subunit protein.
Length = 450
Score = 57.2 bits (132), Expect = 7e-08
Identities = 48/176 (27%), Positives = 76/176 (43%), Gaps = 5/176 (2%)
Frame = +1
Query: 61 ILLPFLLTCAIASAAECENATSLSLMIDSLLATYDRDSPP--DSKIVVNLTLHLRHANIR 234
+LL FLL A E +L L D L A Y P D+ +N+TL + + I
Sbjct: 12 LLLLFLLPAECLGA---EGRLALKLFRD-LFANYTSALRPVADTDQTLNVTLEVTLSQII 67
Query: 235 ESESTVRIQA-DLQMLQNWIDKRLSWNAGEWG-CSTWLVSSERLWGPDVVLLNAA-ATTA 405
+ + ++ L + Q W D L W+ +G + S +W PD+VL N A A
Sbjct: 68 DMDERNQVLTLYLWIRQEWTDAYLRWDPNAYGGLDAIRIPSSLVWRPDIVLYNKADAQPP 127
Query: 406 GDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 573
G + + ++G+V W + + + +P D Q C FGS H ++D
Sbjct: 128 GSASTNVVLRHDGAVRWDAPAITRSSCRVDVAAFPFDAQHCGLTFGSWTHGGHQLD 183
>AF327367-1|AAK14333.1| 450|Homo sapiens nicotinic acetylcholine
receptor subunit alpha 10 protein.
Length = 450
Score = 57.2 bits (132), Expect = 7e-08
Identities = 48/176 (27%), Positives = 76/176 (43%), Gaps = 5/176 (2%)
Frame = +1
Query: 61 ILLPFLLTCAIASAAECENATSLSLMIDSLLATYDRDSPP--DSKIVVNLTLHLRHANIR 234
+LL FLL A E +L L D L A Y P D+ +N+TL + + I
Sbjct: 12 LLLLFLLPAECLGA---EGRLALKLFRD-LFANYTSALRPVADTDQTLNVTLEVTLSQII 67
Query: 235 ESESTVRIQA-DLQMLQNWIDKRLSWNAGEWG-CSTWLVSSERLWGPDVVLLNAA-ATTA 405
+ + ++ L + Q W D L W+ +G + S +W PD+VL N A A
Sbjct: 68 DMDERNQVLTLYLWIRQEWTDAYLRWDPNAYGGLDAIRIPSSLVWRPDIVLYNKADAQPP 127
Query: 406 GDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 573
G + + ++G+V W + + + +P D Q C FGS H ++D
Sbjct: 128 GSASTNVVLRHDGAVRWDAPAITRSSCRVDVAAFPFDAQHCGLTFGSWTHGGHQLD 183
>AF199235-1|AAG00795.2| 450|Homo sapiens nicotinic acetylcholine
receptor subunit alpha 10 protein.
Length = 450
Score = 57.2 bits (132), Expect = 7e-08
Identities = 48/176 (27%), Positives = 76/176 (43%), Gaps = 5/176 (2%)
Frame = +1
Query: 61 ILLPFLLTCAIASAAECENATSLSLMIDSLLATYDRDSPP--DSKIVVNLTLHLRHANIR 234
+LL FLL A E +L L D L A Y P D+ +N+TL + + I
Sbjct: 12 LLLLFLLPAECLGA---EGRLALKLFRD-LFANYTSALRPVADTDQTLNVTLEVTLSQII 67
Query: 235 ESESTVRIQA-DLQMLQNWIDKRLSWNAGEWG-CSTWLVSSERLWGPDVVLLNAA-ATTA 405
+ + ++ L + Q W D L W+ +G + S +W PD+VL N A A
Sbjct: 68 DMDERNQVLTLYLWIRQEWTDAYLRWDPNAYGGLDAIRIPSSLVWRPDIVLYNKADAQPP 127
Query: 406 GDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 573
G + + ++G+V W + + + +P D Q C FGS H ++D
Sbjct: 128 GSASTNVVLRHDGAVRWDAPAITRSSCRVDVAAFPFDAQHCGLTFGSWTHGGHQLD 183
>X01715-1|CAA25861.1| 520|Homo sapiens acetylcholine receptor gamma
chain precursor protein.
Length = 520
Score = 56.8 bits (131), Expect = 1e-07
Identities = 48/183 (26%), Positives = 84/183 (45%), Gaps = 6/183 (3%)
Frame = +1
Query: 58 IILLPFLLTCAIASAAECENATSLSLMIDSLLATYDRDSPPDSKI--VVNLTLHLRHAN- 228
++LL L C + N L+ D L+ YD + P + VVN++L L N
Sbjct: 8 LLLLLLLAVCLGGTQRNLRNQEE-RLLAD-LMQNYDPNLRPAERDSDVVNVSLKLTLTNL 65
Query: 229 IRESESTVRIQADLQMLQNWIDKRLSWNAGEW-GCSTWLVSSERLWGPDVVLLNAAATTA 405
I +E + ++ + W D RL W+ ++ G V S +W PD+VL N
Sbjct: 66 ISLNEREEALTTNVWIEMQWCDYRLRWDPRDYEGLWVLRVPSTMVWRPDIVLENNVDGVF 125
Query: 406 GDYALRARV--SNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFV 579
+ AL V S +G + W+ + S+ + +P D Q C+ F S+ ++++E+D
Sbjct: 126 -EVALYCNVLVSPDGCIYWLPPAIFRSACSISVTYFPFDWQNCSLIFQSQTYSTNEIDLQ 184
Query: 580 IDK 588
+ +
Sbjct: 185 LSQ 187
>S82769-1|AAB39369.1| 467|Homo sapiens GABAA receptor gamma 3
subunit protein.
Length = 467
Score = 56.8 bits (131), Expect = 1e-07
Identities = 42/173 (24%), Positives = 75/173 (43%), Gaps = 6/173 (3%)
Frame = +1
Query: 121 TSLSLMIDSLLATYDRDSPPDSKI---VVNLTLHLRHANIRESESTVRIQADLQMLQNWI 291
T ++L+++ LL YD+ PD I V+++ +++ S + Q D+ Q W
Sbjct: 45 TDVTLILNKLLREYDKKLRPDIGIKPTVIDVDIYVNSIG-PVSSINMEYQIDIFFAQTWT 103
Query: 292 DKRLSWNAGEWGCSTWLVSSERLWGPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIK 462
D RL +N+ + +W PD + N+ A R+ N+G + +
Sbjct: 104 DSRLRFNSTMKILTLNSNMVGLIWIPDTIFRNSKTAEAHWITTPNQLLRIWNDGKILYTL 163
Query: 463 RLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDKRIYSMFESGAW 621
RL I+ +QL N+P D +C F S + +EM + K + +W
Sbjct: 164 RLTINAECQLQLHNFPMDEHSCPLIFSSYGYPKEEMIYRWRKNSVEAADQKSW 216
>AF269144-1|AAF99698.1| 467|Homo sapiens GABAA receptor gamma 3
subunit protein.
Length = 467
Score = 56.8 bits (131), Expect = 1e-07
Identities = 42/173 (24%), Positives = 75/173 (43%), Gaps = 6/173 (3%)
Frame = +1
Query: 121 TSLSLMIDSLLATYDRDSPPDSKI---VVNLTLHLRHANIRESESTVRIQADLQMLQNWI 291
T ++L+++ LL YD+ PD I V+++ +++ S + Q D+ Q W
Sbjct: 45 TDVTLILNKLLREYDKKLRPDIGIKPTVIDVDIYVNSIG-PVSSINMEYQIDIFFAQTWT 103
Query: 292 DKRLSWNAGEWGCSTWLVSSERLWGPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIK 462
D RL +N+ + +W PD + N+ A R+ N+G + +
Sbjct: 104 DSRLRFNSTMKILTLNSNMVGLIWIPDTIFRNSKTAEAHWITTPNQLLRIWNDGKILYTL 163
Query: 463 RLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDKRIYSMFESGAW 621
RL I+ +QL N+P D +C F S + +EM + K + +W
Sbjct: 164 RLTINAECQLQLHNFPMDEHSCPLIFSSYGYPKEEMIYRWRKNSVEAADQKSW 216
>AF228458-1|AAF63215.1| 449|Homo sapiens GABAA receptor gamma 3
subunit protein.
Length = 449
Score = 56.8 bits (131), Expect = 1e-07
Identities = 42/173 (24%), Positives = 75/173 (43%), Gaps = 6/173 (3%)
Frame = +1
Query: 121 TSLSLMIDSLLATYDRDSPPDSKI---VVNLTLHLRHANIRESESTVRIQADLQMLQNWI 291
T ++L+++ LL YD+ PD I V+++ +++ S + Q D+ Q W
Sbjct: 27 TDVTLILNKLLREYDKKLRPDIGIKPTVIDVDIYVNSIG-PVSSINMEYQIDIFFAQTWT 85
Query: 292 DKRLSWNAGEWGCSTWLVSSERLWGPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIK 462
D RL +N+ + +W PD + N+ A R+ N+G + +
Sbjct: 86 DSRLRFNSTMKILTLNSNMVGLIWIPDTIFRNSKTAEAHWITTPNQLLRIWNDGKILYTL 145
Query: 463 RLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDKRIYSMFESGAW 621
RL I+ +QL N+P D +C F S + +EM + K + +W
Sbjct: 146 RLTINAECQLQLHNFPMDEHSCPLIFSSYGYPKEEMIYRWRKNSVEAADQKSW 198
>AC092165-3|AAY24103.1| 520|Homo sapiens unknown protein.
Length = 520
Score = 56.8 bits (131), Expect = 1e-07
Identities = 48/183 (26%), Positives = 84/183 (45%), Gaps = 6/183 (3%)
Frame = +1
Query: 58 IILLPFLLTCAIASAAECENATSLSLMIDSLLATYDRDSPPDSKI--VVNLTLHLRHAN- 228
++LL L C + N L+ D L+ YD + P + VVN++L L N
Sbjct: 8 LLLLLLLAVCLGGTQRNLRNQEE-RLLAD-LMQNYDPNLRPAERDSDVVNVSLKLTLTNL 65
Query: 229 IRESESTVRIQADLQMLQNWIDKRLSWNAGEW-GCSTWLVSSERLWGPDVVLLNAAATTA 405
I +E + ++ + W D RL W+ ++ G V S +W PD+VL N
Sbjct: 66 ISLNEREEALTTNVWIEMQWCDYRLRWDPRDYEGLWVLRVPSTMVWRPDIVLENNVDGVF 125
Query: 406 GDYALRARV--SNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFV 579
+ AL V S +G + W+ + S+ + +P D Q C+ F S+ ++++E+D
Sbjct: 126 -EVALYCNVLVSPDGCIYWLPPAIFRSACSISVTYFPFDWQNCSLIFQSQTYSTNEIDLQ 184
Query: 580 IDK 588
+ +
Sbjct: 185 LSQ 187
>M59216-1|AAA35862.1| 474|Homo sapiens gamma-aminobutyric acid
receptor beta-1 subunit protein.
Length = 474
Score = 56.0 bits (129), Expect = 2e-07
Identities = 47/181 (25%), Positives = 84/181 (46%), Gaps = 8/181 (4%)
Frame = +1
Query: 58 IILLPFLLT--CAIASAAECENATSLSLMIDSLLATYDRDSPPD-SKIVVNLTLHLRHAN 228
++ P ++T C S E N + + +D LL YD PD V++ + + A+
Sbjct: 12 LLSFPVMITMVCCAHSTNEPSNMSYVKETVDRLLKGYDIRLRPDFGGPPVDVGMRIDVAS 71
Query: 229 IRESESTVRIQADLQML--QNWIDKRLSWNAGEWGCSTWLVSSERLWGPDVVLLNAAATT 402
I + S V + L M Q+W DKRLS++ + +++LW PD LN +
Sbjct: 72 I-DMVSEVNMDYTLTMYFQQSWKDKRLSYSGIPLNLTLDNRVADQLWVPDTYFLNDKKSF 130
Query: 403 AGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 573
++ R+ +G+V + R+ + M L +P D Q CT + S + +D+++
Sbjct: 131 VHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIE 190
Query: 574 F 576
F
Sbjct: 191 F 191
>DQ644022-1|ABG35128.1| 456|Homo sapiens 5-HT3 receptor subunit E
splice variant HTR3Ea protein.
Length = 456
Score = 55.6 bits (128), Expect = 2e-07
Identities = 27/110 (24%), Positives = 55/110 (50%), Gaps = 1/110 (0%)
Frame = +1
Query: 286 WIDKRLSWNAGEW-GCSTWLVSSERLWGPDVVLLNAAATTAGDYALRARVSNNGSVSWIK 462
W + +SWN E G + ++++ LW PD+ ++ L A VSN G + + K
Sbjct: 95 WDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEGRIRYKK 154
Query: 463 RLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDKRIYSMFES 612
+ + + ++ + +P D Q CT F S ++ D M ++K ++ + ++
Sbjct: 155 PMKVDSICNLDIFYFPFDQQNCTLTFSSFLYTVDSMLLDMEKEVWEITDA 204
>BC101185-1|AAI01186.1| 374|Homo sapiens HTR3E protein protein.
Length = 374
Score = 55.6 bits (128), Expect = 2e-07
Identities = 27/110 (24%), Positives = 55/110 (50%), Gaps = 1/110 (0%)
Frame = +1
Query: 286 WIDKRLSWNAGEW-GCSTWLVSSERLWGPDVVLLNAAATTAGDYALRARVSNNGSVSWIK 462
W + +SWN E G + ++++ LW PD+ ++ L A VSN G + + K
Sbjct: 24 WDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEGRIRYKK 83
Query: 463 RLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDKRIYSMFES 612
+ + + ++ + +P D Q CT F S ++ D M ++K ++ + ++
Sbjct: 84 PMKVDSICNLDIFYFPFDQQNCTLTFSSFLYTVDSMLLDMEKEVWEITDA 133
>BC101183-1|AAI01184.1| 471|Homo sapiens 5-hydroxytryptamine
(serotonin) receptor 3, family member E protein.
Length = 471
Score = 55.6 bits (128), Expect = 2e-07
Identities = 27/110 (24%), Positives = 55/110 (50%), Gaps = 1/110 (0%)
Frame = +1
Query: 286 WIDKRLSWNAGEW-GCSTWLVSSERLWGPDVVLLNAAATTAGDYALRARVSNNGSVSWIK 462
W + +SWN E G + ++++ LW PD+ ++ L A VSN G + + K
Sbjct: 110 WDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEGRIRYKK 169
Query: 463 RLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDKRIYSMFES 612
+ + + ++ + +P D Q CT F S ++ D M ++K ++ + ++
Sbjct: 170 PMKVDSICNLDIFYFPFDQQNCTLTFSSFLYTVDSMLLDMEKEVWEITDA 219
>BC101182-1|AAI01183.1| 471|Homo sapiens 5-hydroxytryptamine
(serotonin) receptor 3, family member E protein.
Length = 471
Score = 55.6 bits (128), Expect = 2e-07
Identities = 27/110 (24%), Positives = 55/110 (50%), Gaps = 1/110 (0%)
Frame = +1
Query: 286 WIDKRLSWNAGEW-GCSTWLVSSERLWGPDVVLLNAAATTAGDYALRARVSNNGSVSWIK 462
W + +SWN E G + ++++ LW PD+ ++ L A VSN G + + K
Sbjct: 110 WDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEGRIRYKK 169
Query: 463 RLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDKRIYSMFES 612
+ + + ++ + +P D Q CT F S ++ D M ++K ++ + ++
Sbjct: 170 PMKVDSICNLDIFYFPFDQQNCTLTFSSFLYTVDSMLLDMEKEVWEITDA 219
>AY349353-1|AAQ93477.1| 456|Homo sapiens 5-HT3c1 serotonin
receptor-like protein protein.
Length = 456
Score = 55.6 bits (128), Expect = 2e-07
Identities = 27/110 (24%), Positives = 55/110 (50%), Gaps = 1/110 (0%)
Frame = +1
Query: 286 WIDKRLSWNAGEW-GCSTWLVSSERLWGPDVVLLNAAATTAGDYALRARVSNNGSVSWIK 462
W + +SWN E G + ++++ LW PD+ ++ L A VSN G + + K
Sbjct: 95 WDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEGRIRYKK 154
Query: 463 RLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDKRIYSMFES 612
+ + + ++ + +P D Q CT F S ++ D M ++K ++ + ++
Sbjct: 155 PMKVDSICNLDIFYFPFDQQNCTLTFSSFLYTVDSMLLDMEKEVWEITDA 204
>AY349352-1|AAQ93476.1| 441|Homo sapiens 5-HT3c1 serotonin
receptor-like protein protein.
Length = 441
Score = 55.6 bits (128), Expect = 2e-07
Identities = 27/110 (24%), Positives = 55/110 (50%), Gaps = 1/110 (0%)
Frame = +1
Query: 286 WIDKRLSWNAGEW-GCSTWLVSSERLWGPDVVLLNAAATTAGDYALRARVSNNGSVSWIK 462
W + +SWN E G + ++++ LW PD+ ++ L A VSN G + + K
Sbjct: 80 WDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEGRIRYKK 139
Query: 463 RLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDKRIYSMFES 612
+ + + ++ + +P D Q CT F S ++ D M ++K ++ + ++
Sbjct: 140 PMKVDSICNLDIFYFPFDQQNCTLTFSSFLYTVDSMLLDMEKEVWEITDA 189
>AY159813-1|AAO38167.2| 471|Homo sapiens 5-hydroxytryptamine
serotonin receptor 3E protein.
Length = 471
Score = 55.6 bits (128), Expect = 2e-07
Identities = 27/110 (24%), Positives = 55/110 (50%), Gaps = 1/110 (0%)
Frame = +1
Query: 286 WIDKRLSWNAGEW-GCSTWLVSSERLWGPDVVLLNAAATTAGDYALRARVSNNGSVSWIK 462
W + +SWN E G + ++++ LW PD+ ++ L A VSN G + + K
Sbjct: 110 WDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEGRIRYKK 169
Query: 463 RLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDKRIYSMFES 612
+ + + ++ + +P D Q CT F S ++ D M ++K ++ + ++
Sbjct: 170 PMKVDSICNLDIFYFPFDQQNCTLTFSSFLYTVDSMLLDMEKEVWEITDA 219
>X14767-1|CAA32875.1| 474|Homo sapiens GABA-A receptor beta 1
subunit protein.
Length = 474
Score = 55.2 bits (127), Expect = 3e-07
Identities = 47/181 (25%), Positives = 83/181 (45%), Gaps = 8/181 (4%)
Frame = +1
Query: 58 IILLPFLLT--CAIASAAECENATSLSLMIDSLLATYDRDSPPD-SKIVVNLTLHLRHAN 228
++ P ++T C S E N + +D LL YD PD V++ + + A+
Sbjct: 12 LLSFPVMITMVCCAHSTNEPSNMPYVKETVDRLLKGYDIRLRPDFGGPPVDVGMRIDVAS 71
Query: 229 IRESESTVRIQADLQML--QNWIDKRLSWNAGEWGCSTWLVSSERLWGPDVVLLNAAATT 402
I + S V + L M Q+W DKRLS++ + +++LW PD LN +
Sbjct: 72 I-DMVSEVNMDYTLTMYFQQSWKDKRLSYSGIPLNLTLDNRVADQLWVPDTYFLNDKKSF 130
Query: 403 AGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 573
++ R+ +G+V + R+ + M L +P D Q CT + S + +D+++
Sbjct: 131 VHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIE 190
Query: 574 F 576
F
Sbjct: 191 F 191
>L08485-1|AAA58490.1| 462|Homo sapiens GABA-benzodiazepine receptor
alpha-5-subunit protein.
Length = 462
Score = 55.2 bits (127), Expect = 3e-07
Identities = 39/161 (24%), Positives = 74/161 (45%), Gaps = 5/161 (3%)
Frame = +1
Query: 112 ENATSLSLMIDSLLATYD-RDSPPDSKIVVNLTLHLRHANIRE-SESTVRIQADLQMLQN 285
+N T + ++D LL YD R P + + + + + S++ + D+ Q+
Sbjct: 44 DNITIFTRILDGLLDGYDNRLRPGLGERITQVRTDIYVTSFGPVSDTEMEYTIDVFFRQS 103
Query: 286 WIDKRLSWNAGEWGCSTWLVSSERLWGPDVVLLNAAATTAGDYALR---ARVSNNGSVSW 456
W D+RL + + + ++W PD N + A + R+ ++G++ +
Sbjct: 104 WKDERLRFKGPMQRLPLNNLLASKIWTPDTFFHNGKKSIAHNMTTPNKLLRLEDDGTLLY 163
Query: 457 IKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFV 579
RL IS MQL+++P D C KFGS + + E+ +V
Sbjct: 164 TMRLTISAECPMQLEDFPMDAHACPLKFGSYAYPNSEVVYV 204
>BT009830-1|AAP88832.1| 462|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 5 protein.
Length = 462
Score = 55.2 bits (127), Expect = 3e-07
Identities = 39/161 (24%), Positives = 74/161 (45%), Gaps = 5/161 (3%)
Frame = +1
Query: 112 ENATSLSLMIDSLLATYD-RDSPPDSKIVVNLTLHLRHANIRE-SESTVRIQADLQMLQN 285
+N T + ++D LL YD R P + + + + + S++ + D+ Q+
Sbjct: 44 DNITIFTRILDGLLDGYDNRLRPGLGERITQVRTDIYVTSFGPVSDTEMEYTIDVFFRQS 103
Query: 286 WIDKRLSWNAGEWGCSTWLVSSERLWGPDVVLLNAAATTAGDYALR---ARVSNNGSVSW 456
W D+RL + + + ++W PD N + A + R+ ++G++ +
Sbjct: 104 WKDERLRFKGPMQRLPLNNLLASKIWTPDTFFHNGKKSIAHNMTTPNKLLRLEDDGTLLY 163
Query: 457 IKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFV 579
RL IS MQL+++P D C KFGS + + E+ +V
Sbjct: 164 TMRLTISAECPMQLEDFPMDAHACPLKFGSYAYPNSEVVYV 204
>BC113422-1|AAI13423.1| 462|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 5 protein.
Length = 462
Score = 55.2 bits (127), Expect = 3e-07
Identities = 39/161 (24%), Positives = 74/161 (45%), Gaps = 5/161 (3%)
Frame = +1
Query: 112 ENATSLSLMIDSLLATYD-RDSPPDSKIVVNLTLHLRHANIRE-SESTVRIQADLQMLQN 285
+N T + ++D LL YD R P + + + + + S++ + D+ Q+
Sbjct: 44 DNITIFTRILDGLLDGYDNRLRPGLGERITQVRTDIYVTSFGPVSDTEMEYTIDVFFRQS 103
Query: 286 WIDKRLSWNAGEWGCSTWLVSSERLWGPDVVLLNAAATTAGDYALR---ARVSNNGSVSW 456
W D+RL + + + ++W PD N + A + R+ ++G++ +
Sbjct: 104 WKDERLRFKGPMQRLPLNNLLASKIWTPDTFFHNGKKSIAHNMTTPNKLLRLEDDGTLLY 163
Query: 457 IKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFV 579
RL IS MQL+++P D C KFGS + + E+ +V
Sbjct: 164 TMRLTISAECPMQLEDFPMDAHACPLKFGSYAYPNSEVVYV 204
>BC111979-1|AAI11980.1| 462|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 5, precursor protein.
Length = 462
Score = 55.2 bits (127), Expect = 3e-07
Identities = 39/161 (24%), Positives = 74/161 (45%), Gaps = 5/161 (3%)
Frame = +1
Query: 112 ENATSLSLMIDSLLATYD-RDSPPDSKIVVNLTLHLRHANIRE-SESTVRIQADLQMLQN 285
+N T + ++D LL YD R P + + + + + S++ + D+ Q+
Sbjct: 44 DNITIFTRILDGLLDGYDNRLRPGLGERITQVRTDIYVTSFGPVSDTEMEYTIDVFFRQS 103
Query: 286 WIDKRLSWNAGEWGCSTWLVSSERLWGPDVVLLNAAATTAGDYALR---ARVSNNGSVSW 456
W D+RL + + + ++W PD N + A + R+ ++G++ +
Sbjct: 104 WKDERLRFKGPMQRLPLNNLLASKIWTPDTFFHNGKKSIAHNMTTPNKLLRLEDDGTLLY 163
Query: 457 IKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFV 579
RL IS MQL+++P D C KFGS + + E+ +V
Sbjct: 164 TMRLTISAECPMQLEDFPMDAHACPLKFGSYAYPNSEVVYV 204
>S82612-1|AAB37533.2| 478|Homo sapiens 5-hydroxytryptamine type 3AS
receptor subunit protein.
Length = 478
Score = 54.8 bits (126), Expect = 4e-07
Identities = 40/175 (22%), Positives = 76/175 (43%), Gaps = 4/175 (2%)
Frame = +1
Query: 61 ILLPFLLTCAIASAAECENATSLSLMIDSLLATYDRDSPP--DSKIVVNLTLH-LRHANI 231
+LLP LL A + +L + D LL Y + P D + +++ + +A +
Sbjct: 12 LLLPTLLAQGEARRSRNTTRPALLRLSDYLLTNYTKGVRPVRDWRKPTTVSIDVIVYAIL 71
Query: 232 RESESTVRIQADLQMLQNWIDKRLSWNAGEWGCSTWL-VSSERLWGPDVVLLNAAATTAG 408
E + + Q W D+ L WN ++ T L + ++ +W PD+++
Sbjct: 72 NVDEKNQVLTTYIWYRQYWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINELVDVGKS 131
Query: 409 DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 573
+ + G V K L + T S+ + N+P D+Q C+ F S +H +++
Sbjct: 132 PNIPYVYIRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLHTIQDIN 186
>S77554-1|AAB33983.1| 474|Homo sapiens GABAA receptor beta 2
subunit protein.
Length = 474
Score = 54.8 bits (126), Expect = 4e-07
Identities = 45/183 (24%), Positives = 81/183 (44%), Gaps = 9/183 (4%)
Frame = +1
Query: 55 YIILLPFLLTCAIASAAECENATSLSLM---IDSLLATYDRDSPPD---SKIVVNLTLHL 216
Y + F L A A + +++SL+ +D LL YD PD + V + + +
Sbjct: 9 YFGIWSFPLIIAAVCAQSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDI 68
Query: 217 RHANIRESESTVRIQADLQMLQNWIDKRLSWNAGEWGCSTWLVSSERLWGPDVVLLNAAA 396
++ SE + + Q W DKRLS+N + +++LW PD LN
Sbjct: 69 ASIDM-VSEVNMDYTLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLNDKK 127
Query: 397 TTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDE 567
+ ++ R+ +G+V + R+ + M L +P D Q CT + S + +D+
Sbjct: 128 SFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDD 187
Query: 568 MDF 576
++F
Sbjct: 188 IEF 190
>S77553-1|AAB33982.1| 512|Homo sapiens GABAA receptor beta 2
subunit protein.
Length = 512
Score = 54.8 bits (126), Expect = 4e-07
Identities = 45/183 (24%), Positives = 81/183 (44%), Gaps = 9/183 (4%)
Frame = +1
Query: 55 YIILLPFLLTCAIASAAECENATSLSLM---IDSLLATYDRDSPPD---SKIVVNLTLHL 216
Y + F L A A + +++SL+ +D LL YD PD + V + + +
Sbjct: 9 YFGIWSFPLIIAAVCAQSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDI 68
Query: 217 RHANIRESESTVRIQADLQMLQNWIDKRLSWNAGEWGCSTWLVSSERLWGPDVVLLNAAA 396
++ SE + + Q W DKRLS+N + +++LW PD LN
Sbjct: 69 ASIDM-VSEVNMDYTLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLNDKK 127
Query: 397 TTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDE 567
+ ++ R+ +G+V + R+ + M L +P D Q CT + S + +D+
Sbjct: 128 SFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDD 187
Query: 568 MDF 576
++F
Sbjct: 188 IEF 190
>S67368-1|AAB29370.1| 474|Homo sapiens gamma-aminobutyric acid A
receptor beta 2 subunit protein.
Length = 474
Score = 54.8 bits (126), Expect = 4e-07
Identities = 45/183 (24%), Positives = 81/183 (44%), Gaps = 9/183 (4%)
Frame = +1
Query: 55 YIILLPFLLTCAIASAAECENATSLSLM---IDSLLATYDRDSPPD---SKIVVNLTLHL 216
Y + F L A A + +++SL+ +D LL YD PD + V + + +
Sbjct: 9 YFGIWSFPLIIAAVCAQSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDI 68
Query: 217 RHANIRESESTVRIQADLQMLQNWIDKRLSWNAGEWGCSTWLVSSERLWGPDVVLLNAAA 396
++ SE + + Q W DKRLS+N + +++LW PD LN
Sbjct: 69 ASIDM-VSEVNMDYTLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLNDKK 127
Query: 397 TTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDE 567
+ ++ R+ +G+V + R+ + M L +P D Q CT + S + +D+
Sbjct: 128 SFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDD 187
Query: 568 MDF 576
++F
Sbjct: 188 IEF 190
>BC105639-1|AAI05640.1| 474|Homo sapiens GABRB2 protein protein.
Length = 474
Score = 54.8 bits (126), Expect = 4e-07
Identities = 45/183 (24%), Positives = 81/183 (44%), Gaps = 9/183 (4%)
Frame = +1
Query: 55 YIILLPFLLTCAIASAAECENATSLSLM---IDSLLATYDRDSPPD---SKIVVNLTLHL 216
Y + F L A A + +++SL+ +D LL YD PD + V + + +
Sbjct: 9 YFGIWSFPLIIAAVCAQSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDI 68
Query: 217 RHANIRESESTVRIQADLQMLQNWIDKRLSWNAGEWGCSTWLVSSERLWGPDVVLLNAAA 396
++ SE + + Q W DKRLS+N + +++LW PD LN
Sbjct: 69 ASIDM-VSEVNMDYTLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLNDKK 127
Query: 397 TTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDE 567
+ ++ R+ +G+V + R+ + M L +P D Q CT + S + +D+
Sbjct: 128 SFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDD 187
Query: 568 MDF 576
++F
Sbjct: 188 IEF 190
>BC099719-1|AAH99719.1| 474|Homo sapiens GABRB2 protein protein.
Length = 474
Score = 54.8 bits (126), Expect = 4e-07
Identities = 45/183 (24%), Positives = 81/183 (44%), Gaps = 9/183 (4%)
Frame = +1
Query: 55 YIILLPFLLTCAIASAAECENATSLSLM---IDSLLATYDRDSPPD---SKIVVNLTLHL 216
Y + F L A A + +++SL+ +D LL YD PD + V + + +
Sbjct: 9 YFGIWSFPLIIAAVCAQSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDI 68
Query: 217 RHANIRESESTVRIQADLQMLQNWIDKRLSWNAGEWGCSTWLVSSERLWGPDVVLLNAAA 396
++ SE + + Q W DKRLS+N + +++LW PD LN
Sbjct: 69 ASIDM-VSEVNMDYTLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLNDKK 127
Query: 397 TTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDE 567
+ ++ R+ +G+V + R+ + M L +P D Q CT + S + +D+
Sbjct: 128 SFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDD 187
Query: 568 MDF 576
++F
Sbjct: 188 IEF 190
>BC099705-1|AAH99705.1| 474|Homo sapiens GABRB2 protein protein.
Length = 474
Score = 54.8 bits (126), Expect = 4e-07
Identities = 45/183 (24%), Positives = 81/183 (44%), Gaps = 9/183 (4%)
Frame = +1
Query: 55 YIILLPFLLTCAIASAAECENATSLSLM---IDSLLATYDRDSPPD---SKIVVNLTLHL 216
Y + F L A A + +++SL+ +D LL YD PD + V + + +
Sbjct: 9 YFGIWSFPLIIAAVCAQSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDI 68
Query: 217 RHANIRESESTVRIQADLQMLQNWIDKRLSWNAGEWGCSTWLVSSERLWGPDVVLLNAAA 396
++ SE + + Q W DKRLS+N + +++LW PD LN
Sbjct: 69 ASIDM-VSEVNMDYTLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLNDKK 127
Query: 397 TTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDE 567
+ ++ R+ +G+V + R+ + M L +P D Q CT + S + +D+
Sbjct: 128 SFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDD 187
Query: 568 MDF 576
++F
Sbjct: 188 IEF 190
>AJ003080-1|CAA05853.1| 238|Homo sapiens serotonin receptor
protein.
Length = 238
Score = 54.8 bits (126), Expect = 4e-07
Identities = 41/171 (23%), Positives = 74/171 (43%), Gaps = 4/171 (2%)
Frame = +1
Query: 61 ILLPFLLTCAIASAAECENATSLSLMIDSLLATYDRDSPP--DSKIVVNLTLH-LRHANI 231
+LLP LL A + +L + D LL Y + P D + +++ + +A +
Sbjct: 12 LLLPTLLAQGEARRSRNTTRPALLRLSDYLLTNYRKGVRPVRDWRKPTTVSIDVIVYAIL 71
Query: 232 RESESTVRIQADLQMLQNWIDKRLSWNAGEWGCSTWL-VSSERLWGPDVVLLNAAATTAG 408
E + + Q W D+ L WN ++ T L + ++ +W PD+++
Sbjct: 72 NVDEKNQVLTTYIWYRQYWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKS 131
Query: 409 DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNS 561
+ + G V K L + T S+ + N+P D+Q C+ F S +H S
Sbjct: 132 PNIPYVYIRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLHTS 182
>D49394-1|BAA08387.1| 478|Homo sapiens serotonin 5-HT3 receptor
protein.
Length = 478
Score = 54.0 bits (124), Expect = 7e-07
Identities = 40/175 (22%), Positives = 76/175 (43%), Gaps = 4/175 (2%)
Frame = +1
Query: 61 ILLPFLLTCAIASAAECENATSLSLMIDSLLATYDRDSPP--DSKIVVNLTLH-LRHANI 231
+LLP LL A + +L + D LL Y + P D + +++ + +A +
Sbjct: 12 LLLPTLLAQGEARRSRNTTRPALLRLSDYLLTNYRKGVRPVRDWRKPTTVSIDVIVYAIL 71
Query: 232 RESESTVRIQADLQMLQNWIDKRLSWNAGEWGCSTWL-VSSERLWGPDVVLLNAAATTAG 408
E + + Q W D+ L WN ++ T L + ++ +W PD+++
Sbjct: 72 NVDEKNQVLTTYIWYRQYWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKS 131
Query: 409 DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 573
+ + G V K L + T S+ + N+P D+Q C+ F S +H +++
Sbjct: 132 PNIPYVYIRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLHTIQDIN 186
>BT007204-1|AAP35868.1| 484|Homo sapiens 5-hydroxytryptamine
(serotonin) receptor 3A protein.
Length = 484
Score = 54.0 bits (124), Expect = 7e-07
Identities = 40/175 (22%), Positives = 76/175 (43%), Gaps = 4/175 (2%)
Frame = +1
Query: 61 ILLPFLLTCAIASAAECENATSLSLMIDSLLATYDRDSPP--DSKIVVNLTLH-LRHANI 231
+LLP LL A + +L + D LL Y + P D + +++ + +A +
Sbjct: 18 LLLPTLLAQGEARRSRNTTRPALLRLSDYLLTNYRKGVRPVRDWRKPTTVSIDVIVYAIL 77
Query: 232 RESESTVRIQADLQMLQNWIDKRLSWNAGEWGCSTWL-VSSERLWGPDVVLLNAAATTAG 408
E + + Q W D+ L WN ++ T L + ++ +W PD+++
Sbjct: 78 NVDEKNQVLTTYIWYRQYWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKS 137
Query: 409 DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 573
+ + G V K L + T S+ + N+P D+Q C+ F S +H +++
Sbjct: 138 PNIPYVYIRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLHTIQDIN 192
>BC004453-1|AAH04453.2| 478|Homo sapiens 5-hydroxytryptamine
(serotonin) receptor 3A protein.
Length = 478
Score = 54.0 bits (124), Expect = 7e-07
Identities = 40/175 (22%), Positives = 76/175 (43%), Gaps = 4/175 (2%)
Frame = +1
Query: 61 ILLPFLLTCAIASAAECENATSLSLMIDSLLATYDRDSPP--DSKIVVNLTLH-LRHANI 231
+LLP LL A + +L + D LL Y + P D + +++ + +A +
Sbjct: 12 LLLPTLLAQGEARRSRNTTRPALLRLSDYLLTNYRKGVRPVRDWRKPTTVSIDVIVYAIL 71
Query: 232 RESESTVRIQADLQMLQNWIDKRLSWNAGEWGCSTWL-VSSERLWGPDVVLLNAAATTAG 408
E + + Q W D+ L WN ++ T L + ++ +W PD+++
Sbjct: 72 NVDEKNQVLTTYIWYRQYWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKS 131
Query: 409 DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 573
+ + G V K L + T S+ + N+P D+Q C+ F S +H +++
Sbjct: 132 PNIPYVYIRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLHTIQDIN 186
>BC002354-1|AAH02354.1| 478|Homo sapiens 5-hydroxytryptamine
(serotonin) receptor 3A protein.
Length = 478
Score = 54.0 bits (124), Expect = 7e-07
Identities = 40/175 (22%), Positives = 76/175 (43%), Gaps = 4/175 (2%)
Frame = +1
Query: 61 ILLPFLLTCAIASAAECENATSLSLMIDSLLATYDRDSPP--DSKIVVNLTLH-LRHANI 231
+LLP LL A + +L + D LL Y + P D + +++ + +A +
Sbjct: 12 LLLPTLLAQGEARRSRNTTRPALLRLSDYLLTNYRKGVRPVRDWRKPTTVSIDVIVYAIL 71
Query: 232 RESESTVRIQADLQMLQNWIDKRLSWNAGEWGCSTWL-VSSERLWGPDVVLLNAAATTAG 408
E + + Q W D+ L WN ++ T L + ++ +W PD+++
Sbjct: 72 NVDEKNQVLTTYIWYRQYWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKS 131
Query: 409 DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 573
+ + G V K L + T S+ + N+P D+Q C+ F S +H +++
Sbjct: 132 PNIPYVYIRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLHTIQDIN 186
>AJ005205-1|CAA06442.3| 478|Homo sapiens serotonin 3 receptor
protein.
Length = 478
Score = 54.0 bits (124), Expect = 7e-07
Identities = 40/175 (22%), Positives = 76/175 (43%), Gaps = 4/175 (2%)
Frame = +1
Query: 61 ILLPFLLTCAIASAAECENATSLSLMIDSLLATYDRDSPP--DSKIVVNLTLH-LRHANI 231
+LLP LL A + +L + D LL Y + P D + +++ + +A +
Sbjct: 12 LLLPTLLAQGEARRSRNTTRPALLRLSDYLLTNYRKGVRPVRDWRKPTTVSIDVIVYAIL 71
Query: 232 RESESTVRIQADLQMLQNWIDKRLSWNAGEWGCSTWL-VSSERLWGPDVVLLNAAATTAG 408
E + + Q W D+ L WN ++ T L + ++ +W PD+++
Sbjct: 72 NVDEKNQVLTTYIWYRQYWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKS 131
Query: 409 DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 573
+ + G V K L + T S+ + N+P D+Q C+ F S +H +++
Sbjct: 132 PNIPYVYIRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLHTIQDIN 186
>AJ003079-1|CAA05852.1| 478|Homo sapiens 5-hydroxytryptamine3
receptor protein.
Length = 478
Score = 54.0 bits (124), Expect = 7e-07
Identities = 40/175 (22%), Positives = 76/175 (43%), Gaps = 4/175 (2%)
Frame = +1
Query: 61 ILLPFLLTCAIASAAECENATSLSLMIDSLLATYDRDSPP--DSKIVVNLTLH-LRHANI 231
+LLP LL A + +L + D LL Y + P D + +++ + +A +
Sbjct: 12 LLLPTLLAQGEARRSRNTTRPALLRLSDYLLTNYRKGVRPVRDWRKPTTVSIDVIVYAIL 71
Query: 232 RESESTVRIQADLQMLQNWIDKRLSWNAGEWGCSTWL-VSSERLWGPDVVLLNAAATTAG 408
E + + Q W D+ L WN ++ T L + ++ +W PD+++
Sbjct: 72 NVDEKNQVLTTYIWYRQYWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKS 131
Query: 409 DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 573
+ + G V K L + T S+ + N+P D+Q C+ F S +H +++
Sbjct: 132 PNIPYVYIRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLHTIQDIN 186
>AJ003078-1|CAA05851.1| 510|Homo sapiens serotonin receptor
protein.
Length = 510
Score = 54.0 bits (124), Expect = 7e-07
Identities = 40/175 (22%), Positives = 76/175 (43%), Gaps = 4/175 (2%)
Frame = +1
Query: 61 ILLPFLLTCAIASAAECENATSLSLMIDSLLATYDRDSPP--DSKIVVNLTLH-LRHANI 231
+LLP LL A + +L + D LL Y + P D + +++ + +A +
Sbjct: 12 LLLPTLLAQGEARRSRNTTRPALLRLSDYLLTNYRKGVRPVRDWRKPTTVSIDVIVYAIL 71
Query: 232 RESESTVRIQADLQMLQNWIDKRLSWNAGEWGCSTWL-VSSERLWGPDVVLLNAAATTAG 408
E + + Q W D+ L WN ++ T L + ++ +W PD+++
Sbjct: 72 NVDEKNQVLTTYIWYRQYWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKS 131
Query: 409 DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 573
+ + G V K L + T S+ + N+P D+Q C+ F S +H +++
Sbjct: 132 PNIPYVYIRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLHTIQDIN 186
>AF498984-1|AAM21131.1| 478|Homo sapiens 5-hydroxytryptamine
receptor 3A protein.
Length = 478
Score = 54.0 bits (124), Expect = 7e-07
Identities = 40/175 (22%), Positives = 76/175 (43%), Gaps = 4/175 (2%)
Frame = +1
Query: 61 ILLPFLLTCAIASAAECENATSLSLMIDSLLATYDRDSPP--DSKIVVNLTLH-LRHANI 231
+LLP LL A + +L + D LL Y + P D + +++ + +A +
Sbjct: 12 LLLPTLLAQGEARRSRNTTRPALLRLSDYLLTNYRKGVRPVRDWRKPTTVSIDVIVYAIL 71
Query: 232 RESESTVRIQADLQMLQNWIDKRLSWNAGEWGCSTWL-VSSERLWGPDVVLLNAAATTAG 408
E + + Q W D+ L WN ++ T L + ++ +W PD+++
Sbjct: 72 NVDEKNQVLTTYIWYRQYWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKS 131
Query: 409 DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 573
+ + G V K L + T S+ + N+P D+Q C+ F S +H +++
Sbjct: 132 PNIPYVYIRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLHTIQDIN 186
>S81944-1|AAB36480.1| 453|Homo sapiens gamma-aminobutyric acid type
A receptor alpha 6 subunit protein.
Length = 453
Score = 52.4 bits (120), Expect = 2e-06
Identities = 42/166 (25%), Positives = 72/166 (43%), Gaps = 6/166 (3%)
Frame = +1
Query: 124 SLSLMIDSLLATYD-RDSPPDSKIVVNLTLHLRHANIRE-SESTVRIQADLQMLQNWIDK 297
++S ++D+LL YD R P V + + + S+ + D+ Q W D+
Sbjct: 31 NVSRILDNLLEGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTDE 90
Query: 298 RLSWNAGEWGCSTWLVSSERLWGPDVVLLNAAATTAGDYALRA---RVSNNGSVSWIKRL 468
RL + S + ++W PD N + A + R+ NG++ + RL
Sbjct: 91 RLKFGGPTEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTMRL 150
Query: 469 DISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDK-RIYSM 603
I+ M+L N+P D C KFGS + E+ + K +YS+
Sbjct: 151 TINADCPMRLVNFPMDGHACPLKFGSYAYPKSEIIYTWKKGPLYSV 196
>BC099641-1|AAH99641.1| 453|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 6 protein.
Length = 453
Score = 52.4 bits (120), Expect = 2e-06
Identities = 42/166 (25%), Positives = 72/166 (43%), Gaps = 6/166 (3%)
Frame = +1
Query: 124 SLSLMIDSLLATYD-RDSPPDSKIVVNLTLHLRHANIRE-SESTVRIQADLQMLQNWIDK 297
++S ++D+LL YD R P V + + + S+ + D+ Q W D+
Sbjct: 31 NVSRILDNLLEGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTDE 90
Query: 298 RLSWNAGEWGCSTWLVSSERLWGPDVVLLNAAATTAGDYALRA---RVSNNGSVSWIKRL 468
RL + S + ++W PD N + A + R+ NG++ + RL
Sbjct: 91 RLKFGGPTEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTMRL 150
Query: 469 DISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDK-RIYSM 603
I+ M+L N+P D C KFGS + E+ + K +YS+
Sbjct: 151 TINADCPMRLVNFPMDGHACPLKFGSYAYPKSEIIYTWKKGPLYSV 196
>BC099640-1|AAH99640.1| 453|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 6 protein.
Length = 453
Score = 52.4 bits (120), Expect = 2e-06
Identities = 42/166 (25%), Positives = 72/166 (43%), Gaps = 6/166 (3%)
Frame = +1
Query: 124 SLSLMIDSLLATYD-RDSPPDSKIVVNLTLHLRHANIRE-SESTVRIQADLQMLQNWIDK 297
++S ++D+LL YD R P V + + + S+ + D+ Q W D+
Sbjct: 31 NVSRILDNLLEGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTDE 90
Query: 298 RLSWNAGEWGCSTWLVSSERLWGPDVVLLNAAATTAGDYALRA---RVSNNGSVSWIKRL 468
RL + S + ++W PD N + A + R+ NG++ + RL
Sbjct: 91 RLKFGGPTEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTMRL 150
Query: 469 DISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDK-RIYSM 603
I+ M+L N+P D C KFGS + E+ + K +YS+
Sbjct: 151 TINADCPMRLVNFPMDGHACPLKFGSYAYPKSEIIYTWKKGPLYSV 196
>BC096242-1|AAH96242.1| 453|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 6 protein.
Length = 453
Score = 52.4 bits (120), Expect = 2e-06
Identities = 42/166 (25%), Positives = 72/166 (43%), Gaps = 6/166 (3%)
Frame = +1
Query: 124 SLSLMIDSLLATYD-RDSPPDSKIVVNLTLHLRHANIRE-SESTVRIQADLQMLQNWIDK 297
++S ++D+LL YD R P V + + + S+ + D+ Q W D+
Sbjct: 31 NVSRILDNLLEGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTDE 90
Query: 298 RLSWNAGEWGCSTWLVSSERLWGPDVVLLNAAATTAGDYALRA---RVSNNGSVSWIKRL 468
RL + S + ++W PD N + A + R+ NG++ + RL
Sbjct: 91 RLKFGGPTEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTMRL 150
Query: 469 DISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDK-RIYSM 603
I+ M+L N+P D C KFGS + E+ + K +YS+
Sbjct: 151 TINADCPMRLVNFPMDGHACPLKFGSYAYPKSEIIYTWKKGPLYSV 196
>BC096241-1|AAH96241.1| 453|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 6 protein.
Length = 453
Score = 52.4 bits (120), Expect = 2e-06
Identities = 42/166 (25%), Positives = 72/166 (43%), Gaps = 6/166 (3%)
Frame = +1
Query: 124 SLSLMIDSLLATYD-RDSPPDSKIVVNLTLHLRHANIRE-SESTVRIQADLQMLQNWIDK 297
++S ++D+LL YD R P V + + + S+ + D+ Q W D+
Sbjct: 31 NVSRILDNLLEGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTDE 90
Query: 298 RLSWNAGEWGCSTWLVSSERLWGPDVVLLNAAATTAGDYALRA---RVSNNGSVSWIKRL 468
RL + S + ++W PD N + A + R+ NG++ + RL
Sbjct: 91 RLKFGGPTEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTMRL 150
Query: 469 DISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDK-RIYSM 603
I+ M+L N+P D C KFGS + E+ + K +YS+
Sbjct: 151 TINADCPMRLVNFPMDGHACPLKFGSYAYPKSEIIYTWKKGPLYSV 196
>BC028629-1|AAH28629.1| 492|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 3 protein.
Length = 492
Score = 52.4 bits (120), Expect = 2e-06
Identities = 38/159 (23%), Positives = 71/159 (44%), Gaps = 6/159 (3%)
Frame = +1
Query: 112 ENATSLSLMIDSLLATYDRDSPP---DSKIVVNLTLHLRHANIRESESTVRIQADLQMLQ 282
+N T + ++D LL YD P D+ V +++ S++ + D+ Q
Sbjct: 62 DNITIFTRILDRLLDGYDNRLRPGLGDAVTEVKTDIYVTSFG-PVSDTDMEYTIDVFFRQ 120
Query: 283 NWIDKRLSWNAGEWGCSTWLVSSERLWGPDVVLLNAAATTAGDYALR---ARVSNNGSVS 453
W D+RL ++ + + ++W PD N + A + R+ +NG++
Sbjct: 121 TWHDERLKFDGPMKILPLNNLLASKIWTPDTFFHNGKKSVAHNMTTPNKLLRLVDNGTLP 180
Query: 454 WIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEM 570
+ RL I M L+++P D+ C KFGS + + E+
Sbjct: 181 YTMRLTIHAECPMHLEDFPMDVHACPLKFGSYAYTTAEV 219
>X55019-1|CAA38759.1| 517|Homo sapiens acetylcholine receptor delta
subunit protein.
Length = 517
Score = 52.0 bits (119), Expect = 3e-06
Identities = 35/133 (26%), Positives = 62/133 (46%), Gaps = 3/133 (2%)
Frame = +1
Query: 181 DSKIVVNLTLHLRHA-NIRESESTVRIQADLQMLQNWIDKRLSWNAGEWG-CSTWLVSSE 354
+ + V L L L + +++E E T+ ++ W D RL WNA E+G S + +
Sbjct: 49 EESVDVALALTLSNLISLKEVEETLTTNVWIE--HGWTDNRLKWNAEEFGNISVLRLPPD 106
Query: 355 RLWGPDVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCT 531
+W P++VL N + Y+ V + G V W+ + + + +P D Q C+
Sbjct: 107 MVWLPEIVLENNNDGSFQISYSCNVLVYHYGFVYWLPPAIFRSSCPISVTYFPFDWQNCS 166
Query: 532 FKFGSRMHNSDEM 570
KF S + + E+
Sbjct: 167 LKFSSLKYTAKEI 179
>S62908-1|AAB27279.1| 492|Homo sapiens gamma-aminobutyric acidA
receptor alpha 3 subunit protein.
Length = 492
Score = 52.0 bits (119), Expect = 3e-06
Identities = 38/159 (23%), Positives = 71/159 (44%), Gaps = 6/159 (3%)
Frame = +1
Query: 112 ENATSLSLMIDSLLATYDRDSPP---DSKIVVNLTLHLRHANIRESESTVRIQADLQMLQ 282
+N T + ++D LL YD P D+ V +++ S++ + D+ Q
Sbjct: 62 DNITIFTRILDRLLDGYDNRLRPGLGDAVTEVKTDIYVTSFG-PVSDTDMEYTIDVFFRQ 120
Query: 283 NWIDKRLSWNAGEWGCSTWLVSSERLWGPDVVLLNAAATTAGDYALR---ARVSNNGSVS 453
W D+RL ++ + + ++W PD N + A + R+ +NG++
Sbjct: 121 TWHDERLKFDGPMKILPLNNLLASKIWTPDTFFHNGKKSVAHNMTTPNKLLRLVDNGTLL 180
Query: 454 WIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEM 570
+ RL I M L+++P D+ C KFGS + + E+
Sbjct: 181 YTMRLTIHAECPMHLEDFPMDVHACPLKFGSYAYTTAEV 219
>BC093925-1|AAH93925.1| 517|Homo sapiens cholinergic receptor,
nicotinic, delta protein.
Length = 517
Score = 52.0 bits (119), Expect = 3e-06
Identities = 35/133 (26%), Positives = 62/133 (46%), Gaps = 3/133 (2%)
Frame = +1
Query: 181 DSKIVVNLTLHLRHA-NIRESESTVRIQADLQMLQNWIDKRLSWNAGEWG-CSTWLVSSE 354
+ + V L L L + +++E E T+ ++ W D RL WNA E+G S + +
Sbjct: 49 EESVDVALALTLSNLISLKEVEETLTTNVWIE--HGWTDNRLKWNAEEFGNISVLRLPPD 106
Query: 355 RLWGPDVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCT 531
+W P++VL N + Y+ V + G V W+ + + + +P D Q C+
Sbjct: 107 MVWLPEIVLENNNDGSFQISYSCNVLVYHYGFVYWLPPAIFRSSCPISVTYFPFDWQNCS 166
Query: 532 FKFGSRMHNSDEM 570
KF S + + E+
Sbjct: 167 LKFSSLKYTAKEI 179
>BC093923-1|AAH93923.1| 517|Homo sapiens cholinergic receptor,
nicotinic, delta protein.
Length = 517
Score = 52.0 bits (119), Expect = 3e-06
Identities = 35/133 (26%), Positives = 62/133 (46%), Gaps = 3/133 (2%)
Frame = +1
Query: 181 DSKIVVNLTLHLRHA-NIRESESTVRIQADLQMLQNWIDKRLSWNAGEWG-CSTWLVSSE 354
+ + V L L L + +++E E T+ ++ W D RL WNA E+G S + +
Sbjct: 49 EESVDVALALTLSNLISLKEVEETLTTNVWIE--HGWTDNRLKWNAEEFGNISVLRLPPD 106
Query: 355 RLWGPDVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCT 531
+W P++VL N + Y+ V + G V W+ + + + +P D Q C+
Sbjct: 107 MVWLPEIVLENNNDGSFQISYSCNVLVYHYGFVYWLPPAIFRSSCPISVTYFPFDWQNCS 166
Query: 532 FKFGSRMHNSDEM 570
KF S + + E+
Sbjct: 167 LKFSSLKYTAKEI 179
>AF166361-1|AAG12455.1| 492|Homo sapiens GABA receptor subunit
alpha 3 protein.
Length = 492
Score = 52.0 bits (119), Expect = 3e-06
Identities = 38/159 (23%), Positives = 71/159 (44%), Gaps = 6/159 (3%)
Frame = +1
Query: 112 ENATSLSLMIDSLLATYDRDSPP---DSKIVVNLTLHLRHANIRESESTVRIQADLQMLQ 282
+N T + ++D LL YD P D+ V +++ S++ + D+ Q
Sbjct: 62 DNITIFTRILDRLLDGYDNRLRPGLGDAVTEVKTDIYVTSFG-PVSDTDMEYTIDVFFRQ 120
Query: 283 NWIDKRLSWNAGEWGCSTWLVSSERLWGPDVVLLNAAATTAGDYALR---ARVSNNGSVS 453
W D+RL ++ + + ++W PD N + A + R+ +NG++
Sbjct: 121 TWHDERLKFDGPMKILPLNNLLASKIWTPDTFFHNGKKSVAHNMTTPNKLLRLVDNGTLL 180
Query: 454 WIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEM 570
+ RL I M L+++P D+ C KFGS + + E+
Sbjct: 181 YTMRLTIHAECPMHLEDFPMDVHACPLKFGSYAYTTAEV 219
>AC092165-2|AAY24102.1| 517|Homo sapiens unknown protein.
Length = 517
Score = 52.0 bits (119), Expect = 3e-06
Identities = 35/133 (26%), Positives = 62/133 (46%), Gaps = 3/133 (2%)
Frame = +1
Query: 181 DSKIVVNLTLHLRHA-NIRESESTVRIQADLQMLQNWIDKRLSWNAGEWG-CSTWLVSSE 354
+ + V L L L + +++E E T+ ++ W D RL WNA E+G S + +
Sbjct: 49 EESVDVALALTLSNLISLKEVEETLTTNVWIE--HGWTDNRLKWNAEEFGNISVLRLPPD 106
Query: 355 RLWGPDVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCT 531
+W P++VL N + Y+ V + G V W+ + + + +P D Q C+
Sbjct: 107 MVWLPEIVLENNNDGSFQISYSCNVLVYHYGFVYWLPPAIFRSSCPISVTYFPFDWQNCS 166
Query: 532 FKFGSRMHNSDEM 570
KF S + + E+
Sbjct: 167 LKFSSLKYTAKEI 179
>Z23141-1|CAA80672.1| 479|Homo sapiens cholinergic receptor,
nicotinic, alpha polypeptide 7 protein.
Length = 479
Score = 51.6 bits (118), Expect = 4e-06
Identities = 39/159 (24%), Positives = 72/159 (45%), Gaps = 3/159 (1%)
Frame = +1
Query: 169 DSPPDSKIVVNLTLHLRHANIRESESTVRIQADLQMLQNWIDKRLSWNAGEW-GCSTWLV 345
DS P + + +L+L L+ ++ E + LQM +W D L WN E+ G T
Sbjct: 24 DSQPLT-VYFSLSL-LQIMDVDEKNQVLTTNIWLQM--SWTDHYLQWNVSEYPGVKTVRF 79
Query: 346 SSERLWGPDVVLLNAAATTA-GDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQ 522
++W PD++L N+A + V+++G ++ + + + +P D+Q
Sbjct: 80 PDGQIWKPDILLYNSADERFDATFHTNVLVNSSGHCQYLPPGIFKSSCYIDVRWFPFDVQ 139
Query: 523 TCTFKFGSRMHNSDEMDFVIDKR-IYSMFESGAWDVTAL 636
C KFGS + +D + + I +G WD+ +
Sbjct: 140 HCKLKFGSWSYGGWSLDLQMQEADISGYIPNGEWDLVGI 178
>Y08420-1|CAA69697.1| 502|Homo sapiens nicotinic acetylcholine
receptor alpha7 subunit precursor protein.
Length = 502
Score = 51.6 bits (118), Expect = 4e-06
Identities = 39/159 (24%), Positives = 72/159 (45%), Gaps = 3/159 (1%)
Frame = +1
Query: 169 DSPPDSKIVVNLTLHLRHANIRESESTVRIQADLQMLQNWIDKRLSWNAGEW-GCSTWLV 345
DS P + + +L+L L+ ++ E + LQM +W D L WN E+ G T
Sbjct: 47 DSQPLT-VYFSLSL-LQIMDVDEKNQVLTTNIWLQM--SWTDHYLQWNVSEYPGVKTVRF 102
Query: 346 SSERLWGPDVVLLNAAATTA-GDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQ 522
++W PD++L N+A + V+++G ++ + + + +P D+Q
Sbjct: 103 PDGQIWKPDILLYNSADERFDATFHTNVLVNSSGHCQYLPPGIFKSSCYIDVRWFPFDVQ 162
Query: 523 TCTFKFGSRMHNSDEMDFVIDKR-IYSMFESGAWDVTAL 636
C KFGS + +D + + I +G WD+ +
Sbjct: 163 HCKLKFGSWSYGGWSLDLQMQEADISGYIPNGEWDLVGI 201
>X70297-1|CAA49778.1| 502|Homo sapiens neuronal nicotinic
acetylocholine receptor alpha-7 subunit protein.
Length = 502
Score = 51.6 bits (118), Expect = 4e-06
Identities = 39/159 (24%), Positives = 72/159 (45%), Gaps = 3/159 (1%)
Frame = +1
Query: 169 DSPPDSKIVVNLTLHLRHANIRESESTVRIQADLQMLQNWIDKRLSWNAGEW-GCSTWLV 345
DS P + + +L+L L+ ++ E + LQM +W D L WN E+ G T
Sbjct: 47 DSQPLT-VYFSLSL-LQIMDVDEKNQVLTTNIWLQM--SWTDHYLQWNVSEYPGVKTVRF 102
Query: 346 SSERLWGPDVVLLNAAATTA-GDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQ 522
++W PD++L N+A + V+++G ++ + + + +P D+Q
Sbjct: 103 PDGQIWKPDILLYNSADERFDATFHTNVLVNSSGHCQYLPPGIFKSSCYIDVRWFPFDVQ 162
Query: 523 TCTFKFGSRMHNSDEMDFVIDKR-IYSMFESGAWDVTAL 636
C KFGS + +D + + I +G WD+ +
Sbjct: 163 HCKLKFGSWSYGGWSLDLQMQEADISGYIPNGEWDLVGI 201
>U62436-1|AAB40114.1| 502|Homo sapiens nicotinic acetylcholine
receptor alpha7 subunit precursor protein.
Length = 502
Score = 51.6 bits (118), Expect = 4e-06
Identities = 39/159 (24%), Positives = 72/159 (45%), Gaps = 3/159 (1%)
Frame = +1
Query: 169 DSPPDSKIVVNLTLHLRHANIRESESTVRIQADLQMLQNWIDKRLSWNAGEW-GCSTWLV 345
DS P + + +L+L L+ ++ E + LQM +W D L WN E+ G T
Sbjct: 47 DSQPLT-VYFSLSL-LQIMDVDEKNQVLTTNIWLQM--SWTDHYLQWNVSEYPGVKTVRF 102
Query: 346 SSERLWGPDVVLLNAAATTA-GDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQ 522
++W PD++L N+A + V+++G ++ + + + +P D+Q
Sbjct: 103 PDGQIWKPDILLYNSADERFDATFHTNVLVNSSGHCQYLPPGIFKSSCYIDVRWFPFDVQ 162
Query: 523 TCTFKFGSRMHNSDEMDFVIDKR-IYSMFESGAWDVTAL 636
C KFGS + +D + + I +G WD+ +
Sbjct: 163 HCKLKFGSWSYGGWSLDLQMQEADISGYIPNGEWDLVGI 201
>AJ586911-1|CAE52911.1| 502|Homo sapiens nicotinic acetylcholine
alpha-7 subunit protein.
Length = 502
Score = 51.6 bits (118), Expect = 4e-06
Identities = 39/159 (24%), Positives = 72/159 (45%), Gaps = 3/159 (1%)
Frame = +1
Query: 169 DSPPDSKIVVNLTLHLRHANIRESESTVRIQADLQMLQNWIDKRLSWNAGEW-GCSTWLV 345
DS P + + +L+L L+ ++ E + LQM +W D L WN E+ G T
Sbjct: 47 DSQPLT-VYFSLSL-LQIMDVDEKNQVLTTNIWLQM--SWTDHYLQWNVSEYPGVKTVRF 102
Query: 346 SSERLWGPDVVLLNAAATTA-GDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQ 522
++W PD++L N+A + V+++G ++ + + + +P D+Q
Sbjct: 103 PDGQIWKPDILLYNSADERFDATFHTNVLVNSSGHCQYLPPGIFKSSCYIDVRWFPFDVQ 162
Query: 523 TCTFKFGSRMHNSDEMDFVIDKR-IYSMFESGAWDVTAL 636
C KFGS + +D + + I +G WD+ +
Sbjct: 163 HCKLKFGSWSYGGWSLDLQMQEADISGYIPNGEWDLVGI 201
>U30461-1|AAB52519.1| 554|Homo sapiens GABAA receptor subunit
alpha4 protein.
Length = 554
Score = 51.2 bits (117), Expect = 5e-06
Identities = 41/156 (26%), Positives = 66/156 (42%), Gaps = 5/156 (3%)
Frame = +1
Query: 136 MIDSLLATYD-RDSPPDSKIVVNLTLHLRHANIRE-SESTVRIQADLQMLQNWIDKRLSW 309
++DSLL YD R P V + + + S+ + D+ Q WIDKRL +
Sbjct: 51 ILDSLLDGYDNRLRPGFGGPVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWIDKRLKY 110
Query: 310 NAGEWGCSTWLVSSERLWGPDVVLLNAAATTAGDYALRA---RVSNNGSVSWIKRLDIST 480
+ + ++W PD N + + + R+ NG++ + RL IS
Sbjct: 111 DGPIEILRLNNMMVTKVWTPDTFFRNGKKSVSHNMTAPNKLFRIMRNGTILYTMRLTISA 170
Query: 481 PISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDK 588
M+L ++P D C KFGS + EM + K
Sbjct: 171 ECPMRLVDFPMDGHACPLKFGSYAYPKSEMIYTWTK 206
>BC110597-1|AAI10598.1| 411|Homo sapiens ligand-gated ion channel,
zinc activated 1 protein.
Length = 411
Score = 51.2 bits (117), Expect = 5e-06
Identities = 27/98 (27%), Positives = 46/98 (46%)
Frame = +1
Query: 283 NWIDKRLSWNAGEWGCSTWLVSSERLWGPDVVLLNAAATTAGDYALRARVSNNGSVSWIK 462
+W+D RL+WN + E LW P + +L A D + +ARV +G V
Sbjct: 89 SWLDTRLAWNTSAHPRHAITLPWESLWTPRLTILEALWVDWRDQSPQARVDQDGHVKLNL 148
Query: 463 RLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDF 576
L T + +L ++P D C+ F + + + E++F
Sbjct: 149 ALTTETNCNFELLHFPRDHSNCSLSFYALSNTAMELEF 186
>BC035055-1|AAH35055.1| 554|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 4 protein.
Length = 554
Score = 51.2 bits (117), Expect = 5e-06
Identities = 41/156 (26%), Positives = 66/156 (42%), Gaps = 5/156 (3%)
Frame = +1
Query: 136 MIDSLLATYD-RDSPPDSKIVVNLTLHLRHANIRE-SESTVRIQADLQMLQNWIDKRLSW 309
++DSLL YD R P V + + + S+ + D+ Q WIDKRL +
Sbjct: 51 ILDSLLDGYDNRLRPGFGGPVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWIDKRLKY 110
Query: 310 NAGEWGCSTWLVSSERLWGPDVVLLNAAATTAGDYALRA---RVSNNGSVSWIKRLDIST 480
+ + ++W PD N + + + R+ NG++ + RL IS
Sbjct: 111 DGPIEILRLNNMMVTKVWTPDTFFRNGKKSVSHNMTAPNKLFRIMRNGTILYTMRLTISA 170
Query: 481 PISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDK 588
M+L ++P D C KFGS + EM + K
Sbjct: 171 ECPMRLVDFPMDGHACPLKFGSYAYPKSEMIYTWTK 206
>AF512521-1|AAO20969.1| 411|Homo sapiens ligand-gated ion channel
subunit protein.
Length = 411
Score = 51.2 bits (117), Expect = 5e-06
Identities = 27/98 (27%), Positives = 46/98 (46%)
Frame = +1
Query: 283 NWIDKRLSWNAGEWGCSTWLVSSERLWGPDVVLLNAAATTAGDYALRARVSNNGSVSWIK 462
+W+D RL+WN + E LW P + +L A D + +ARV +G V
Sbjct: 89 SWLDTRLAWNTSAHPRHAITLPWESLWTPRLTILEALWVDWRDQSPQARVDQDGHVKLNL 148
Query: 463 RLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDF 576
L T + +L ++P D C+ F + + + E++F
Sbjct: 149 ALTTETNCNFELLHFPRDHSNCSLSFYALSNTAMELEF 186
>BC022449-1|AAH22449.1| 474|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, beta 1 protein.
Length = 474
Score = 50.8 bits (116), Expect = 6e-06
Identities = 46/181 (25%), Positives = 83/181 (45%), Gaps = 8/181 (4%)
Frame = +1
Query: 58 IILLPFLLT--CAIASAAECENATSLSLMIDSLLATYDRDSPPD-SKIVVNLTLHLRHAN 228
++ P ++T C S E N + + +D LL YD PD V++ + + A+
Sbjct: 12 LLSFPVMITMVCCAHSTNEPSNMSYVKETVDRLLKGYDIRLRPDFGGPPVDVGMRIDVAS 71
Query: 229 IRESESTVRIQADLQML--QNWIDKRLSWNAGEWGCSTWLVSSERLWGPDVVLLNAAATT 402
I + S V + L M Q+W DKRLS++ + +++L PD LN +
Sbjct: 72 I-DMVSEVNMDYTLTMYFQQSWKDKRLSYSGIPLNLTLDNRVADQLCVPDTYFLNDKKSF 130
Query: 403 AGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 573
++ R+ +G+V + R+ + M L +P D Q CT + S + +D+++
Sbjct: 131 VHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIE 190
Query: 574 F 576
F
Sbjct: 191 F 191
>AB223030-1|BAE19924.1| 411|Homo sapiens ligand-gated ion-channel
receptor L2 protein.
Length = 411
Score = 50.8 bits (116), Expect = 6e-06
Identities = 27/98 (27%), Positives = 46/98 (46%)
Frame = +1
Query: 283 NWIDKRLSWNAGEWGCSTWLVSSERLWGPDVVLLNAAATTAGDYALRARVSNNGSVSWIK 462
+W+D RL+WN + E LW P + +L A D + +ARV +G V
Sbjct: 89 SWLDTRLAWNTSAHPRHAITLPWESLWTPRLTILEALWVDWRDQSPQARVDQDGHVKLNL 148
Query: 463 RLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDF 576
L T + +L ++P D C+ F + + + E++F
Sbjct: 149 ALATETNCNFELLHFPRDHSNCSLSFYALSNTAMELEF 186
>U95367-1|AAC51357.1| 440|Homo sapiens GABA-A receptor pi subunit
protein.
Length = 440
Score = 50.4 bits (115), Expect = 8e-06
Identities = 43/164 (26%), Positives = 80/164 (48%), Gaps = 7/164 (4%)
Frame = +1
Query: 106 ECENATSLSLM-IDSLLATYDRDSPPD-SKIVVNLTLHLRHANIRE-SESTVRIQADLQM 276
E + LSL ++L A Y++ P+ V + L L A+I SES + A + +
Sbjct: 29 EVGRSDKLSLPGFENLTAGYNKFLRPNFGGEPVQIALTLDIASISSISESNMDYTATIYL 88
Query: 277 LQNWIDKRLSWNAGE-WGCSTWLVSSERLWGPDVVLLNAAATTAGDYALR---ARVSNNG 444
Q W+D+RL + + + LV E LW PD ++ + + + + R+ +NG
Sbjct: 89 RQRWMDQRLVFEGNKSFTLDARLV--EFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNG 146
Query: 445 SVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDF 576
+V + R+ + +M L +P D QTC + S ++ ++++F
Sbjct: 147 TVLYALRITTTVACNMDLSKYPMDTQTCKLQLESWGYDGNDVEF 190
>BC109106-1|AAI09107.1| 440|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, pi protein.
Length = 440
Score = 50.4 bits (115), Expect = 8e-06
Identities = 43/164 (26%), Positives = 80/164 (48%), Gaps = 7/164 (4%)
Frame = +1
Query: 106 ECENATSLSLM-IDSLLATYDRDSPPD-SKIVVNLTLHLRHANIRE-SESTVRIQADLQM 276
E + LSL ++L A Y++ P+ V + L L A+I SES + A + +
Sbjct: 29 EVGRSDKLSLPGFENLTAGYNKFLRPNFGGEPVQIALTLDIASISSISESNMDYTATIYL 88
Query: 277 LQNWIDKRLSWNAGE-WGCSTWLVSSERLWGPDVVLLNAAATTAGDYALR---ARVSNNG 444
Q W+D+RL + + + LV E LW PD ++ + + + + R+ +NG
Sbjct: 89 RQRWMDQRLVFEGNKSFTLDARLV--EFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNG 146
Query: 445 SVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDF 576
+V + R+ + +M L +P D QTC + S ++ ++++F
Sbjct: 147 TVLYALRITTTVACNMDLSKYPMDTQTCKLQLESWGYDGNDVEF 190
>BC109105-1|AAI09106.1| 440|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, pi protein.
Length = 440
Score = 50.4 bits (115), Expect = 8e-06
Identities = 43/164 (26%), Positives = 80/164 (48%), Gaps = 7/164 (4%)
Frame = +1
Query: 106 ECENATSLSLM-IDSLLATYDRDSPPD-SKIVVNLTLHLRHANIRE-SESTVRIQADLQM 276
E + LSL ++L A Y++ P+ V + L L A+I SES + A + +
Sbjct: 29 EVGRSDKLSLPGFENLTAGYNKFLRPNFGGEPVQIALTLDIASISSISESNMDYTATIYL 88
Query: 277 LQNWIDKRLSWNAGE-WGCSTWLVSSERLWGPDVVLLNAAATTAGDYALR---ARVSNNG 444
Q W+D+RL + + + LV E LW PD ++ + + + + R+ +NG
Sbjct: 89 RQRWMDQRLVFEGNKSFTLDARLV--EFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNG 146
Query: 445 SVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDF 576
+V + R+ + +M L +P D QTC + S ++ ++++F
Sbjct: 147 TVLYALRITTTVACNMDLSKYPMDTQTCKLQLESWGYDGNDVEF 190
>BC074865-1|AAH74865.1| 440|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, pi protein.
Length = 440
Score = 50.4 bits (115), Expect = 8e-06
Identities = 43/164 (26%), Positives = 80/164 (48%), Gaps = 7/164 (4%)
Frame = +1
Query: 106 ECENATSLSLM-IDSLLATYDRDSPPD-SKIVVNLTLHLRHANIRE-SESTVRIQADLQM 276
E + LSL ++L A Y++ P+ V + L L A+I SES + A + +
Sbjct: 29 EVGRSDKLSLPGFENLTAGYNKFLRPNFGGEPVQIALTLDIASISSISESNMDYTATIYL 88
Query: 277 LQNWIDKRLSWNAGE-WGCSTWLVSSERLWGPDVVLLNAAATTAGDYALR---ARVSNNG 444
Q W+D+RL + + + LV E LW PD ++ + + + + R+ +NG
Sbjct: 89 RQRWMDQRLVFEGNKSFTLDARLV--EFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNG 146
Query: 445 SVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDF 576
+V + R+ + +M L +P D QTC + S ++ ++++F
Sbjct: 147 TVLYALRITTTVACNMDLSKYPMDTQTCKLQLESWGYDGNDVEF 190
>BC074810-1|AAH74810.1| 440|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, pi protein.
Length = 440
Score = 50.4 bits (115), Expect = 8e-06
Identities = 43/164 (26%), Positives = 80/164 (48%), Gaps = 7/164 (4%)
Frame = +1
Query: 106 ECENATSLSLM-IDSLLATYDRDSPPD-SKIVVNLTLHLRHANIRE-SESTVRIQADLQM 276
E + LSL ++L A Y++ P+ V + L L A+I SES + A + +
Sbjct: 29 EVGRSDKLSLPGFENLTAGYNKFLRPNFGGEPVQIALTLDIASISSISESNMDYTATIYL 88
Query: 277 LQNWIDKRLSWNAGE-WGCSTWLVSSERLWGPDVVLLNAAATTAGDYALR---ARVSNNG 444
Q W+D+RL + + + LV E LW PD ++ + + + + R+ +NG
Sbjct: 89 RQRWMDQRLVFEGNKSFTLDARLV--EFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNG 146
Query: 445 SVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDF 576
+V + R+ + +M L +P D QTC + S ++ ++++F
Sbjct: 147 TVLYALRITTTVACNMDLSKYPMDTQTCKLQLESWGYDGNDVEF 190
>AF009702-1|AAC24194.1| 440|Homo sapiens GABA-A receptor pi subunit
protein.
Length = 440
Score = 50.4 bits (115), Expect = 8e-06
Identities = 43/164 (26%), Positives = 80/164 (48%), Gaps = 7/164 (4%)
Frame = +1
Query: 106 ECENATSLSLM-IDSLLATYDRDSPPD-SKIVVNLTLHLRHANIRE-SESTVRIQADLQM 276
E + LSL ++L A Y++ P+ V + L L A+I SES + A + +
Sbjct: 29 EVGRSDKLSLPGFENLTAGYNKFLRPNFGGEPVQIALTLDIASISSISESNMDYTATIYL 88
Query: 277 LQNWIDKRLSWNAGE-WGCSTWLVSSERLWGPDVVLLNAAATTAGDYALR---ARVSNNG 444
Q W+D+RL + + + LV E LW PD ++ + + + + R+ +NG
Sbjct: 89 RQRWMDQRLVFEGNKSFTLDARLV--EFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNG 146
Query: 445 SVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDF 576
+V + R+ + +M L +P D QTC + S ++ ++++F
Sbjct: 147 TVLYALRITTTVACNMDLSKYPMDTQTCKLQLESWGYDGNDVEF 190
>U40583-1|AAA83561.1| 502|Homo sapiens alpha 7 neuronal nicotinic
acetylcholine receptor protein.
Length = 502
Score = 50.0 bits (114), Expect = 1e-05
Identities = 39/159 (24%), Positives = 70/159 (44%), Gaps = 3/159 (1%)
Frame = +1
Query: 169 DSPPDSKIVVNLTLHLRHANIRESESTVRIQADLQMLQNWIDKRLSWNAGEW-GCSTWLV 345
DS P + + +L L L+ ++ E + LQM +W D L WN E+ G T
Sbjct: 47 DSQPLT-VYFSLNL-LQIMDVDEKNQVLTTNIWLQM--SWTDHYLQWNVSEYPGVKTVRF 102
Query: 346 SSERLWGPDVVLLNAAATTA-GDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQ 522
++W PD++L N+A + V+ +G ++ + + + +P D+Q
Sbjct: 103 PDGQIWKPDILLYNSADERFDATFHTNVLVNPSGHCQYLPPGIFKSSCYIDVRWFPFDVQ 162
Query: 523 TCTFKFGSRMHNSDEMDFVIDKR-IYSMFESGAWDVTAL 636
C KFGS + +D + + I +G WD+ +
Sbjct: 163 HCKLKFGSWSYGGWSLDLQMQEADISGYIPNGEWDLVGI 201
>BC033801-1|AAH33801.1| 452|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, delta protein.
Length = 452
Score = 50.0 bits (114), Expect = 1e-05
Identities = 39/149 (26%), Positives = 68/149 (45%), Gaps = 5/149 (3%)
Frame = +1
Query: 139 IDSLLATYDRDSPPD-SKIVVNLTLHLRHANIRE-SESTVRIQADLQMLQNWIDKRLSWN 312
+D L+A Y R+ P VN+ L L A+I SE+ + + + Q+W D RLS+N
Sbjct: 44 LDGLIAGYARNFRPGIGGPPVNVALALEVASIDHISEANMEYTMTVFLHQSWRDSRLSYN 103
Query: 313 AGEWGCSTWLVSSERLWGPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTP 483
++LW PD ++NA + D + R+ +G + + R+ +
Sbjct: 104 HTNETLGLDSRFVDKLWLPDTFIVNAKSAWFHDVTVENKLIRLQPDGVILYSIRITSTVA 163
Query: 484 ISMQLDNWPNDMQTCTFKFGSRMHNSDEM 570
M L +P D Q C S ++S+++
Sbjct: 164 CDMDLAKYPMDEQECMLDLESYGYSSEDI 192
>AL391845-4|CAI15436.1| 452|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, delta protein.
Length = 452
Score = 50.0 bits (114), Expect = 1e-05
Identities = 39/149 (26%), Positives = 68/149 (45%), Gaps = 5/149 (3%)
Frame = +1
Query: 139 IDSLLATYDRDSPPD-SKIVVNLTLHLRHANIRE-SESTVRIQADLQMLQNWIDKRLSWN 312
+D L+A Y R+ P VN+ L L A+I SE+ + + + Q+W D RLS+N
Sbjct: 44 LDGLIAGYARNFRPGIGGPPVNVALALEVASIDHISEANMEYTMTVFLHQSWRDSRLSYN 103
Query: 313 AGEWGCSTWLVSSERLWGPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTP 483
++LW PD ++NA + D + R+ +G + + R+ +
Sbjct: 104 HTNETLGLDSRFVDKLWLPDTFIVNAKSAWFHDVTVENKLIRLQPDGVILYSIRITSTVA 163
Query: 484 ISMQLDNWPNDMQTCTFKFGSRMHNSDEM 570
M L +P D Q C S ++S+++
Sbjct: 164 CDMDLAKYPMDEQECMLDLESYGYSSEDI 192
>AF385585-1|AAK68111.1| 502|Homo sapiens nicotinic cholinergic
receptor alpha 7 protein.
Length = 502
Score = 50.0 bits (114), Expect = 1e-05
Identities = 39/159 (24%), Positives = 70/159 (44%), Gaps = 3/159 (1%)
Frame = +1
Query: 169 DSPPDSKIVVNLTLHLRHANIRESESTVRIQADLQMLQNWIDKRLSWNAGEW-GCSTWLV 345
DS P + + +L L L+ ++ E + LQM +W D L WN E+ G T
Sbjct: 47 DSQPLT-VYFSLNL-LQIMDVDEKNQVLTTNIWLQM--SWTDHYLQWNVSEYPGVKTVRF 102
Query: 346 SSERLWGPDVVLLNAAATTA-GDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQ 522
++W PD++L N+A + V+ +G ++ + + + +P D+Q
Sbjct: 103 PDGQIWKPDILLYNSADERFDATFHTNVLVNPSGHCQYLPPGIFKSSCYIDVRWFPFDVQ 162
Query: 523 TCTFKFGSRMHNSDEMDFVIDKR-IYSMFESGAWDVTAL 636
C KFGS + +D + + I +G WD+ +
Sbjct: 163 HCKLKFGSWSYGGWSLDLQMQEADISGYIPNGEWDLVGI 201
>AF016917-1|AAB70007.1| 452|Homo sapiens GABA-A receptor delta
subunit protein.
Length = 452
Score = 50.0 bits (114), Expect = 1e-05
Identities = 39/149 (26%), Positives = 68/149 (45%), Gaps = 5/149 (3%)
Frame = +1
Query: 139 IDSLLATYDRDSPPD-SKIVVNLTLHLRHANIRE-SESTVRIQADLQMLQNWIDKRLSWN 312
+D L+A Y R+ P VN+ L L A+I SE+ + + + Q+W D RLS+N
Sbjct: 44 LDGLIAGYARNFRPGIGGPPVNVALALEVASIDHISEANMEYTMTVFLHQSWRDSRLSYN 103
Query: 313 AGEWGCSTWLVSSERLWGPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTP 483
++LW PD ++NA + D + R+ +G + + R+ +
Sbjct: 104 HTNETLGLDSRFVDKLWLPDTFIVNAKSAWFHDVTVENKLIRLQPDGVILYSIRITSTVA 163
Query: 484 ISMQLDNWPNDMQTCTFKFGSRMHNSDEM 570
M L +P D Q C S ++S+++
Sbjct: 164 CDMDLAKYPMDEQECMLDLESYGYSSEDI 192
>BC074795-1|AAH74795.1| 467|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, gamma 2 protein.
Length = 467
Score = 49.2 bits (112), Expect = 2e-05
Identities = 37/170 (21%), Positives = 73/170 (42%), Gaps = 5/170 (2%)
Frame = +1
Query: 127 LSLMIDSLLATYDRDSPPDSKIVVNLTLHLRHANIRESESTVRIQ--ADLQMLQNWIDKR 300
+++++++LL YD PD + L + N + + ++ D+ Q W D+R
Sbjct: 66 VTVILNNLLEGYDNKLRPDIGVKPTLIHTDMYVNSIGPVNAINMEYTIDIFFAQTWYDRR 125
Query: 301 LSWNAGEWGCSTWLVSSERLWGPDVVLLNAAATTAGDYAL---RARVSNNGSVSWIKRLD 471
L +N+ ++W PD N+ A R+ N+G V + RL
Sbjct: 126 LKFNSTIKVLRLNSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYTLRLT 185
Query: 472 ISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDKRIYSMFESGAW 621
I +QL N+P D +C +F S + +E+ + + + ++ +W
Sbjct: 186 IDAECQLQLHNFPMDEHSCPLEFSSYGYPREEIVYQWKRSSVEVGDTRSW 235
>BC069348-1|AAH69348.1| 467|Homo sapiens gamma-aminobutyric acid A
receptor, gamma 2, isoform 2 precursor protein.
Length = 467
Score = 49.2 bits (112), Expect = 2e-05
Identities = 37/170 (21%), Positives = 73/170 (42%), Gaps = 5/170 (2%)
Frame = +1
Query: 127 LSLMIDSLLATYDRDSPPDSKIVVNLTLHLRHANIRESESTVRIQ--ADLQMLQNWIDKR 300
+++++++LL YD PD + L + N + + ++ D+ Q W D+R
Sbjct: 66 VTVILNNLLEGYDNKLRPDIGVKPTLIHTDMYVNSIGPVNAINMEYTIDIFFAQTWYDRR 125
Query: 301 LSWNAGEWGCSTWLVSSERLWGPDVVLLNAAATTAGDYAL---RARVSNNGSVSWIKRLD 471
L +N+ ++W PD N+ A R+ N+G V + RL
Sbjct: 126 LKFNSTIKVLRLNSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYTLRLT 185
Query: 472 ISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDKRIYSMFESGAW 621
I +QL N+P D +C +F S + +E+ + + + ++ +W
Sbjct: 186 IDAECQLQLHNFPMDEHSCPLEFSSYGYPREEIVYQWKRSSVEVGDTRSW 235
>BC059389-1|AAH59389.1| 475|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, gamma 2 protein.
Length = 475
Score = 49.2 bits (112), Expect = 2e-05
Identities = 37/170 (21%), Positives = 73/170 (42%), Gaps = 5/170 (2%)
Frame = +1
Query: 127 LSLMIDSLLATYDRDSPPDSKIVVNLTLHLRHANIRESESTVRIQ--ADLQMLQNWIDKR 300
+++++++LL YD PD + L + N + + ++ D+ Q W D+R
Sbjct: 66 VTVILNNLLEGYDNKLRPDIGVKPTLIHTDMYVNSIGPVNAINMEYTIDIFFAQTWYDRR 125
Query: 301 LSWNAGEWGCSTWLVSSERLWGPDVVLLNAAATTAGDYAL---RARVSNNGSVSWIKRLD 471
L +N+ ++W PD N+ A R+ N+G V + RL
Sbjct: 126 LKFNSTIKVLRLNSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYTLRLT 185
Query: 472 ISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDKRIYSMFESGAW 621
I +QL N+P D +C +F S + +E+ + + + ++ +W
Sbjct: 186 IDAECQLQLHNFPMDEHSCPLEFSSYGYPREEIVYQWKRSSVEVGDTRSW 235
>AF165124-1|AAD50273.1| 467|Homo sapiens gamma-aminobutyric acid A
receptor gamma 2 protein.
Length = 467
Score = 49.2 bits (112), Expect = 2e-05
Identities = 37/170 (21%), Positives = 73/170 (42%), Gaps = 5/170 (2%)
Frame = +1
Query: 127 LSLMIDSLLATYDRDSPPDSKIVVNLTLHLRHANIRESESTVRIQ--ADLQMLQNWIDKR 300
+++++++LL YD PD + L + N + + ++ D+ Q W D+R
Sbjct: 66 VTVILNNLLEGYDNKLRPDIGVKPTLIHTDMYVNSIGPVNAINMEYTIDIFFAQTWYDRR 125
Query: 301 LSWNAGEWGCSTWLVSSERLWGPDVVLLNAAATTAGDYAL---RARVSNNGSVSWIKRLD 471
L +N+ ++W PD N+ A R+ N+G V + RL
Sbjct: 126 LKFNSTIKVLRLNSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYTLRLT 185
Query: 472 ISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDKRIYSMFESGAW 621
I +QL N+P D +C +F S + +E+ + + + ++ +W
Sbjct: 186 IDAECQLQLHNFPMDEHSCPLEFSSYGYPREEIVYQWKRSSVEVGDTRSW 235
>X52008-1|CAA36257.1| 452|Homo sapiens inhibitory glycine receptor
protein.
Length = 452
Score = 48.4 bits (110), Expect = 3e-05
Identities = 31/117 (26%), Positives = 55/117 (47%), Gaps = 4/117 (3%)
Frame = +1
Query: 238 SESTVRIQADLQMLQNWIDKRLSWNAGEWGCSTWLVSS-ERLWGPDVVLLNAAATTAGDY 414
+E+T+ + ++ + Q W D RL+++ S + +W PD+ N D
Sbjct: 86 TETTMDYRVNIFLRQQWNDSRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHDV 145
Query: 415 ALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDF 576
R+S NG V + RL ++ M L N+P D+QTCT + S + +++ F
Sbjct: 146 TTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNFPMDVQTCTMQLESFGYTMNDLIF 202
>U77731-2|AAB38273.1| 360|Homo sapiens glycine receptor alpha 2B
subunit protein.
Length = 360
Score = 48.4 bits (110), Expect = 3e-05
Identities = 31/117 (26%), Positives = 55/117 (47%), Gaps = 4/117 (3%)
Frame = +1
Query: 238 SESTVRIQADLQMLQNWIDKRLSWNAGEWGCSTWLVSS-ERLWGPDVVLLNAAATTAGDY 414
+E+T+ + ++ + Q W D RL+++ S + +W PD+ N D
Sbjct: 86 AETTMDYRVNIFLRQQWNDSRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHDV 145
Query: 415 ALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDF 576
R+S NG V + RL ++ M L N+P D+QTCT + S + +++ F
Sbjct: 146 TTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNFPMDVQTCTMQLESFGYTMNDLIF 202
>U77731-1|AAB38272.1| 360|Homo sapiens glycine receptor alpha 2
subunit protein.
Length = 360
Score = 48.4 bits (110), Expect = 3e-05
Identities = 31/117 (26%), Positives = 55/117 (47%), Gaps = 4/117 (3%)
Frame = +1
Query: 238 SESTVRIQADLQMLQNWIDKRLSWNAGEWGCSTWLVSS-ERLWGPDVVLLNAAATTAGDY 414
+E+T+ + ++ + Q W D RL+++ S + +W PD+ N D
Sbjct: 86 TETTMDYRVNIFLRQQWNDSRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHDV 145
Query: 415 ALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDF 576
R+S NG V + RL ++ M L N+P D+QTCT + S + +++ F
Sbjct: 146 TTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNFPMDVQTCTMQLESFGYTMNDLIF 202
>CR450343-1|CAG29339.1| 452|Homo sapiens GLRA2 protein.
Length = 452
Score = 48.4 bits (110), Expect = 3e-05
Identities = 31/117 (26%), Positives = 55/117 (47%), Gaps = 4/117 (3%)
Frame = +1
Query: 238 SESTVRIQADLQMLQNWIDKRLSWNAGEWGCSTWLVSS-ERLWGPDVVLLNAAATTAGDY 414
+E+T+ + ++ + Q W D RL+++ S + +W PD+ N D
Sbjct: 86 AETTMDYRVNIFLRQQWNDSRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHDV 145
Query: 415 ALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDF 576
R+S NG V + RL ++ M L N+P D+QTCT + S + +++ F
Sbjct: 146 TTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNFPMDVQTCTMQLESFGYTMNDLIF 202
>BC032864-1|AAH32864.1| 452|Homo sapiens glycine receptor, alpha 2
protein.
Length = 452
Score = 48.4 bits (110), Expect = 3e-05
Identities = 31/117 (26%), Positives = 55/117 (47%), Gaps = 4/117 (3%)
Frame = +1
Query: 238 SESTVRIQADLQMLQNWIDKRLSWNAGEWGCSTWLVSS-ERLWGPDVVLLNAAATTAGDY 414
+E+T+ + ++ + Q W D RL+++ S + +W PD+ N D
Sbjct: 86 TETTMDYRVNIFLRQQWNDSRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHDV 145
Query: 415 ALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDF 576
R+S NG V + RL ++ M L N+P D+QTCT + S + +++ F
Sbjct: 146 TTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNFPMDVQTCTMQLESFGYTMNDLIF 202
>AY437084-1|AAR87843.1| 452|Homo sapiens glycine receptor alpha2
subunit B protein.
Length = 452
Score = 48.4 bits (110), Expect = 3e-05
Identities = 31/117 (26%), Positives = 55/117 (47%), Gaps = 4/117 (3%)
Frame = +1
Query: 238 SESTVRIQADLQMLQNWIDKRLSWNAGEWGCSTWLVSS-ERLWGPDVVLLNAAATTAGDY 414
+E+T+ + ++ + Q W D RL+++ S + +W PD+ N D
Sbjct: 86 AETTMDYRVNIFLRQQWNDSRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHDV 145
Query: 415 ALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDF 576
R+S NG V + RL ++ M L N+P D+QTCT + S + +++ F
Sbjct: 146 TTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNFPMDVQTCTMQLESFGYTMNDLIF 202
>AY437083-1|AAR87842.1| 452|Homo sapiens glycine receptor alpha2
subunit A protein.
Length = 452
Score = 48.4 bits (110), Expect = 3e-05
Identities = 31/117 (26%), Positives = 55/117 (47%), Gaps = 4/117 (3%)
Frame = +1
Query: 238 SESTVRIQADLQMLQNWIDKRLSWNAGEWGCSTWLVSS-ERLWGPDVVLLNAAATTAGDY 414
+E+T+ + ++ + Q W D RL+++ S + +W PD+ N D
Sbjct: 86 TETTMDYRVNIFLRQQWNDSRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHDV 145
Query: 415 ALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDF 576
R+S NG V + RL ++ M L N+P D+QTCT + S + +++ F
Sbjct: 146 TTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNFPMDVQTCTMQLESFGYTMNDLIF 202
>AF053495-1|AAC35290.1| 452|Homo sapiens glycine receptor alpha 2
subunit protein.
Length = 452
Score = 48.4 bits (110), Expect = 3e-05
Identities = 31/117 (26%), Positives = 55/117 (47%), Gaps = 4/117 (3%)
Frame = +1
Query: 238 SESTVRIQADLQMLQNWIDKRLSWNAGEWGCSTWLVSS-ERLWGPDVVLLNAAATTAGDY 414
+E+T+ + ++ + Q W D RL+++ S + +W PD+ N D
Sbjct: 86 TETTMDYRVNIFLRQQWNDSRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHDV 145
Query: 415 ALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDF 576
R+S NG V + RL ++ M L N+P D+QTCT + S + +++ F
Sbjct: 146 TTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNFPMDVQTCTMQLESFGYTMNDLIF 202
>X15376-1|CAA33437.1| 467|Homo sapiens GABA-A receptor gamma 2
subunit protein.
Length = 467
Score = 48.0 bits (109), Expect = 4e-05
Identities = 37/170 (21%), Positives = 73/170 (42%), Gaps = 5/170 (2%)
Frame = +1
Query: 127 LSLMIDSLLATYDRDSPPDSKIVVNLTLHLRHANIRESESTVRIQ--ADLQMLQNWIDKR 300
+++++++LL YD PD + L + N + + ++ D+ Q W D+R
Sbjct: 66 VTVILNNLLEGYDNKLRPDIGVKPTLIHTDMYVNSIGPVNAINMEYTIDIFFAQMWYDRR 125
Query: 301 LSWNAGEWGCSTWLVSSERLWGPDVVLLNAAATTAGDYAL---RARVSNNGSVSWIKRLD 471
L +N+ ++W PD N+ A R+ N+G V + RL
Sbjct: 126 LKFNSTIKVLRLNSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYSLRLT 185
Query: 472 ISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDKRIYSMFESGAW 621
I +QL N+P D +C +F S + +E+ + + + ++ +W
Sbjct: 186 IDAECQLQLHNFPMDEHSCPLEFSSYGYPREEIVYQWKRSSVEVGDTRSW 235
>BC111802-1|AAI11803.1| 465|Homo sapiens CHRNG protein protein.
Length = 465
Score = 47.6 bits (108), Expect = 6e-05
Identities = 35/135 (25%), Positives = 60/135 (44%), Gaps = 5/135 (3%)
Frame = +1
Query: 70 PFLLTCAIASAAECENATSLSLMIDSLLATYDRDSPPDSKI--VVNLTLHLRHAN-IRES 240
P LL +A + ++ L+ YD + P + VVN++L L N I +
Sbjct: 7 PLLLLLLLAVCLGAQGRNQEERLLADLMQNYDPNLRPAERDSDVVNVSLKLTLTNLISLN 66
Query: 241 ESTVRIQADLQMLQNWIDKRLSWNAGEW-GCSTWLVSSERLWGPDVVLLNAAAT-TAGDY 414
E + ++ + W D RL W+ ++ G V S +W PD+VL N + T + +
Sbjct: 67 EREEALTTNVWIEMQWCDYRLRWDPRDYEGLWVLRVPSTMVWRPDIVLENKSQTYSTNEI 126
Query: 415 ALRARVSNNGSVSWI 459
L+ + S+ WI
Sbjct: 127 DLQLSQEDGQSIEWI 141
>AK122638-1|BAC85499.1| 266|Homo sapiens yte protein of 76kDa)
(LCP2). protein.
Length = 266
Score = 47.6 bits (108), Expect = 6e-05
Identities = 25/86 (29%), Positives = 39/86 (45%)
Frame = +1
Query: 283 NWIDKRLSWNAGEWGCSTWLVSSERLWGPDVVLLNAAATTAGDYALRARVSNNGSVSWIK 462
+W+D RL+WN + E LW P + +L A D + +ARV +G V
Sbjct: 90 SWLDTRLAWNTSAHPRHAITLPWESLWTPRLTILEALWVDWRDQSPQARVDQDGHVKLNL 149
Query: 463 RLDISTPISMQLDNWPNDMQTCTFKF 540
L T + +L ++P D C+ F
Sbjct: 150 ALTTETNCNFELLHFPRDHSNCSLSF 175
>BC031087-1|AAH31087.1| 465|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, gamma 1 protein.
Length = 465
Score = 47.2 bits (107), Expect = 8e-05
Identities = 38/170 (22%), Positives = 71/170 (41%), Gaps = 5/170 (2%)
Frame = +1
Query: 127 LSLMIDSLLATYDRDSPPDSKIVVNLTLHLRHANIRESESTVRIQ--ADLQMLQNWIDKR 300
++ +++SLL YD PD + + + N + ++ D+ Q W D R
Sbjct: 64 ITQILNSLLQGYDNKLRPDIGVRPTVIETDVYVNSIGPVDPINMEYTIDIIFAQTWFDSR 123
Query: 301 LSWNAGEWGCSTWLVSSERLWGPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLD 471
L +N+ ++W PD N+ + A R+ N+G V + RL
Sbjct: 124 LKFNSTMKVLMLNSNMVGKIWIPDTFFRNSRKSDAHWITTPNRLLRIWNDGRVLYTLRLT 183
Query: 472 ISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDKRIYSMFESGAW 621
I+ +QL N+P D +C +F S + +E+++ K + + W
Sbjct: 184 INAECYLQLHNFPMDEHSCPLEFSSYGYPKNEIEYKWKKPSVEVADPKYW 233
>BC109211-1|AAI09212.1| 632|Homo sapiens gamma-aminobutyric acid
(GABA) receptor, theta protein.
Length = 632
Score = 46.4 bits (105), Expect = 1e-04
Identities = 37/145 (25%), Positives = 61/145 (42%), Gaps = 5/145 (3%)
Frame = +1
Query: 109 CENATSLSLMIDSLLATYD-RDSPPDSKIVVNLTLHLRHANIRE-SESTVRIQADLQMLQ 282
C N + ++D +L+ YD R P V + + + +I + SE + + Q
Sbjct: 53 CANEAVVQKILDRVLSRYDVRLRPNFGGAPVPVRISIYVTSIEQISEMNMDYTITMFFHQ 112
Query: 283 NWIDKRLSWNAGEWGCSTWLVSSERLWGPDVVLLNAAATTAGDYALRARVSN---NGSVS 453
W D RL++ + E+LW PD LN+ D + RV +G+V
Sbjct: 113 TWKDSRLAYYETTLNLTLDYRMHEKLWVPDCYFLNSKDAFVHDVTVENRVFQLHPDGTVR 172
Query: 454 WIKRLDISTPISMQLDNWPNDMQTC 528
+ RL + S+ L +P D Q C
Sbjct: 173 YGIRLTTTAACSLDLHKFPMDKQAC 197
>BC109210-1|AAI09211.1| 632|Homo sapiens gamma-aminobutyric acid
(GABA) receptor, theta protein.
Length = 632
Score = 46.4 bits (105), Expect = 1e-04
Identities = 37/145 (25%), Positives = 61/145 (42%), Gaps = 5/145 (3%)
Frame = +1
Query: 109 CENATSLSLMIDSLLATYD-RDSPPDSKIVVNLTLHLRHANIRE-SESTVRIQADLQMLQ 282
C N + ++D +L+ YD R P V + + + +I + SE + + Q
Sbjct: 53 CANEAVVQKILDRVLSRYDVRLRPNFGGAPVPVRISIYVTSIEQISEMNMDYTITMFFHQ 112
Query: 283 NWIDKRLSWNAGEWGCSTWLVSSERLWGPDVVLLNAAATTAGDYALRARVSN---NGSVS 453
W D RL++ + E+LW PD LN+ D + RV +G+V
Sbjct: 113 TWKDSRLAYYETTLNLTLDYRMHEKLWVPDCYFLNSKDAFVHDVTVENRVFQLHPDGTVR 172
Query: 454 WIKRLDISTPISMQLDNWPNDMQTC 528
+ RL + S+ L +P D Q C
Sbjct: 173 YGIRLTTTAACSLDLHKFPMDKQAC 197
>AF189259-1|AAF70380.1| 632|Homo sapiens GABA-A receptor theta
subunit protein.
Length = 632
Score = 46.4 bits (105), Expect = 1e-04
Identities = 37/145 (25%), Positives = 61/145 (42%), Gaps = 5/145 (3%)
Frame = +1
Query: 109 CENATSLSLMIDSLLATYD-RDSPPDSKIVVNLTLHLRHANIRE-SESTVRIQADLQMLQ 282
C N + ++D +L+ YD R P V + + + +I + SE + + Q
Sbjct: 53 CANEAVVQKILDRVLSRYDVRLRPNFGGAPVPVRISIYVTSIEQISEMNMDYTITMFFHQ 112
Query: 283 NWIDKRLSWNAGEWGCSTWLVSSERLWGPDVVLLNAAATTAGDYALRARVSN---NGSVS 453
W D RL++ + E+LW PD LN+ D + RV +G+V
Sbjct: 113 TWKDSRLAYYETTLNLTLDYRMHEKLWVPDCYFLNSKDAFVHDVTVENRVFQLHPDGTVR 172
Query: 454 WIKRLDISTPISMQLDNWPNDMQTC 528
+ RL + S+ L +P D Q C
Sbjct: 173 YGIRLTTTAACSLDLHKFPMDKQAC 197
>AF144648-1|AAD51172.1| 627|Homo sapiens GABA-A receptor theta
protein.
Length = 627
Score = 46.4 bits (105), Expect = 1e-04
Identities = 37/145 (25%), Positives = 61/145 (42%), Gaps = 5/145 (3%)
Frame = +1
Query: 109 CENATSLSLMIDSLLATYD-RDSPPDSKIVVNLTLHLRHANIRE-SESTVRIQADLQMLQ 282
C N + ++D +L+ YD R P V + + + +I + SE + + Q
Sbjct: 48 CANEAVVQKILDRVLSRYDVRLRPNFGGAPVPVRISIYVTSIEQISEMNMDYTITMFFHQ 107
Query: 283 NWIDKRLSWNAGEWGCSTWLVSSERLWGPDVVLLNAAATTAGDYALRARVSN---NGSVS 453
W D RL++ + E+LW PD LN+ D + RV +G+V
Sbjct: 108 TWKDSRLAYYETTLNLTLDYRMHEKLWVPDCYFLNSKDAFVHDVTVENRVFQLHPDGTVR 167
Query: 454 WIKRLDISTPISMQLDNWPNDMQTC 528
+ RL + S+ L +P D Q C
Sbjct: 168 YGIRLTTTAACSLDLHKFPMDKQAC 192
>Y09763-1|CAA70903.1| 506|Homo sapiens GABRE protein.
Length = 506
Score = 45.6 bits (103), Expect = 2e-04
Identities = 43/183 (23%), Positives = 80/183 (43%), Gaps = 10/183 (5%)
Frame = +1
Query: 130 SLMIDSLLATYDRDSPPD-----SKIVVNLTLH-LRHANIRESESTVRIQADLQMLQNWI 291
S +++++L+ YD P + + V ++++ L +I + E T+ D+ Q W
Sbjct: 72 SRILNTILSNYDHKLRPGIGEKPTVVTVEISVNSLGPLSILDMEYTI----DIIFSQTWY 127
Query: 292 DKRLSWN-AGEWGCSTWLVSSERLWGPDVVLLNAAATTAGDYAL---RARVSNNGSVSWI 459
D+RL +N E V S+ LW PD N+ T + + R+ +G V +
Sbjct: 128 DERLCYNDTFESLVLNGNVVSQ-LWIPDTFFRNSKRTHEHEITMPNQMVRIYKDGKVLYT 186
Query: 460 KRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDKRIYSMFESGAWDVTALX 639
R+ I S+ + +P D +C F S + +EM + + + E +W + L
Sbjct: 187 IRMTIDAGCSLHMLRFPMDSHSCPLSFSSFSYPENEMIYKWENFKLEINEKNSWKLFQLD 246
Query: 640 XCG 648
G
Sbjct: 247 FTG 249
>BC096083-1|AAH96083.1| 198|Homo sapiens CHRNB4 protein protein.
Length = 198
Score = 45.6 bits (103), Expect = 2e-04
Identities = 33/123 (26%), Positives = 59/123 (47%), Gaps = 6/123 (4%)
Frame = +1
Query: 64 LLPFLLTCAIASAAECENATSLSLMIDSLL--ATYDRDSPP--DSKIVVNLTLHLRHAN- 228
L+ F L A+ C A + ++D LL Y+ P S ++++ L L A
Sbjct: 7 LVLFFLV-ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQL 65
Query: 229 IRESESTVRIQADLQMLQNWIDKRLSWNAGEW-GCSTWLVSSERLWGPDVVLLNAAATTA 405
I +E + ++ + Q W D RL+WN+ + G + + ++R+W PD+VL N + T
Sbjct: 66 ISVNEREQIMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNKSLRTG 125
Query: 406 GDY 414
+
Sbjct: 126 STW 128
>BC096081-1|AAH96081.1| 198|Homo sapiens CHRNB4 protein protein.
Length = 198
Score = 45.6 bits (103), Expect = 2e-04
Identities = 33/123 (26%), Positives = 59/123 (47%), Gaps = 6/123 (4%)
Frame = +1
Query: 64 LLPFLLTCAIASAAECENATSLSLMIDSLL--ATYDRDSPP--DSKIVVNLTLHLRHAN- 228
L+ F L A+ C A + ++D LL Y+ P S ++++ L L A
Sbjct: 7 LVLFFLV-ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQL 65
Query: 229 IRESESTVRIQADLQMLQNWIDKRLSWNAGEW-GCSTWLVSSERLWGPDVVLLNAAATTA 405
I +E + ++ + Q W D RL+WN+ + G + + ++R+W PD+VL N + T
Sbjct: 66 ISVNEREQIMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNKSLRTG 125
Query: 406 GDY 414
+
Sbjct: 126 STW 128
>X52009-1|CAA36258.1| 449|Homo sapiens inhibitory glycine receptor
protein.
Length = 449
Score = 44.8 bits (101), Expect = 4e-04
Identities = 29/117 (24%), Positives = 55/117 (47%), Gaps = 4/117 (3%)
Frame = +1
Query: 238 SESTVRIQADLQMLQNWIDKRLSWNAGEWGCSTWLVSS-ERLWGPDVVLLNAAATTAGDY 414
+E+T+ + ++ + Q W D RL++N S + +W PD+ N +
Sbjct: 80 AETTMDYRVNIFLRQQWNDPRLAYNEYPDDSLDLDPSMLDSIWKPDLFFANEKGAHFHEI 139
Query: 415 ALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDF 576
R+S NG+V + R+ ++ M L N+P D+QTC + S + +++ F
Sbjct: 140 TTDNKLLRISRNGNVLYSIRITLTLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIF 196
>BC114947-1|AAI14948.1| 457|Homo sapiens GLRA1 protein protein.
Length = 457
Score = 44.8 bits (101), Expect = 4e-04
Identities = 29/117 (24%), Positives = 55/117 (47%), Gaps = 4/117 (3%)
Frame = +1
Query: 238 SESTVRIQADLQMLQNWIDKRLSWNAGEWGCSTWLVSS-ERLWGPDVVLLNAAATTAGDY 414
+E+T+ + ++ + Q W D RL++N S + +W PD+ N +
Sbjct: 80 AETTMDYRVNIFLRQQWNDPRLAYNEYPDDSLDLDPSMLDSIWKPDLFFANEKGAHFHEI 139
Query: 415 ALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDF 576
R+S NG+V + R+ ++ M L N+P D+QTC + S + +++ F
Sbjct: 140 TTDNKLLRISRNGNVLYSIRITLTLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIF 196
>BC074980-1|AAH74980.1| 449|Homo sapiens glycine receptor, alpha 1
(startle disease/hyperekplexia) protein.
Length = 449
Score = 44.8 bits (101), Expect = 4e-04
Identities = 29/117 (24%), Positives = 55/117 (47%), Gaps = 4/117 (3%)
Frame = +1
Query: 238 SESTVRIQADLQMLQNWIDKRLSWNAGEWGCSTWLVSS-ERLWGPDVVLLNAAATTAGDY 414
+E+T+ + ++ + Q W D RL++N S + +W PD+ N +
Sbjct: 80 AETTMDYRVNIFLRQQWNDPRLAYNEYPDDSLDLDPSMLDSIWKPDLFFANEKGAHFHEI 139
Query: 415 ALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDF 576
R+S NG+V + R+ ++ M L N+P D+QTC + S + +++ F
Sbjct: 140 TTDNKLLRISRNGNVLYSIRITLTLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIF 196
>Y09765-1|CAA70904.1| 506|Homo sapiens GABA receptor epsilon
subunit protein.
Length = 506
Score = 44.0 bits (99), Expect = 7e-04
Identities = 41/174 (23%), Positives = 77/174 (44%), Gaps = 10/174 (5%)
Frame = +1
Query: 130 SLMIDSLLATYDRDSPPD-----SKIVVNLTLH-LRHANIRESESTVRIQADLQMLQNWI 291
S +++++L+ YD P + + V ++++ L +I + E T+ D+ Q W
Sbjct: 72 SRILNTILSNYDHKLRPGIGEKPTVVTVEISVNSLGPLSILDMEYTI----DIIFSQTWY 127
Query: 292 DKRLSWN-AGEWGCSTWLVSSERLWGPDVVLLNAAATTAGDYAL---RARVSNNGSVSWI 459
D+RL +N E V S+ LW PD N+ T + + R+ +G V +
Sbjct: 128 DERLCYNDTFESLVLNGNVVSQ-LWIPDTFFRNSKRTHEHEITMPNQMVRIYKDGKVLYT 186
Query: 460 KRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDKRIYSMFESGAW 621
R+ I S+ + +P D +C F S + +EM + + + E +W
Sbjct: 187 IRMTIDAGCSLHMLRFPMDSHSCPLSFSSFSYPENEMIYKWENFKLEINEKNSW 240
>U93917-1|AAC39917.1| 449|Homo sapiens glycine receptor alpha 3
subunit protein.
Length = 449
Score = 44.0 bits (99), Expect = 7e-04
Identities = 44/181 (24%), Positives = 79/181 (43%), Gaps = 9/181 (4%)
Frame = +1
Query: 61 ILLPFLLTCAIASAAECENATSLSLMIDSLLAT---YDRDSPPDSK-IVVNLTLHLRHAN 228
+LL + T SA S S +D L+ YD P+ K VN+T ++ +
Sbjct: 21 LLLSLVATKETDSARSRSAPMSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINS 80
Query: 229 IRE-SESTVRIQADLQMLQNWIDKRLSWNAGEWGCSTWLVSS-ERLWGPDVVLLNAAATT 402
+E+T+ + ++ + Q W D RL+++ S + +W PD+ N
Sbjct: 81 FGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGAN 140
Query: 403 AGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 573
+ R+ NG+V + RL ++ M L N+P D+QTC + S + +++
Sbjct: 141 FHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFPMDVQTCIMQLESFGYTMNDLI 200
Query: 574 F 576
F
Sbjct: 201 F 201
>U92283-1|AAB94645.1| 506|Homo sapiens GABA-A receptor epsilon
subunit protein.
Length = 506
Score = 44.0 bits (99), Expect = 7e-04
Identities = 41/174 (23%), Positives = 77/174 (44%), Gaps = 10/174 (5%)
Frame = +1
Query: 130 SLMIDSLLATYDRDSPPD-----SKIVVNLTLH-LRHANIRESESTVRIQADLQMLQNWI 291
S +++++L+ YD P + + V ++++ L +I + E T+ D+ Q W
Sbjct: 72 SRILNTILSNYDHKLRPGIGEKPTVVTVEISVNSLGPLSILDMEYTI----DIIFSQTWY 127
Query: 292 DKRLSWN-AGEWGCSTWLVSSERLWGPDVVLLNAAATTAGDYAL---RARVSNNGSVSWI 459
D+RL +N E V S+ LW PD N+ T + + R+ +G V +
Sbjct: 128 DERLCYNDTFESLVLNGNVVSQ-LWIPDTFFRNSKRTHEHEITMPNQMVRIYKDGKVLYT 186
Query: 460 KRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDKRIYSMFESGAW 621
R+ I S+ + +P D +C F S + +EM + + + E +W
Sbjct: 187 IRMTIDAGCSLHMLRFPMDSHSCPLSFSSFSYPENEMIYKWENFKLEINEKNSW 240
>BC036086-1|AAH36086.1| 464|Homo sapiens glycine receptor, alpha 3
protein.
Length = 464
Score = 44.0 bits (99), Expect = 7e-04
Identities = 44/181 (24%), Positives = 79/181 (43%), Gaps = 9/181 (4%)
Frame = +1
Query: 61 ILLPFLLTCAIASAAECENATSLSLMIDSLLAT---YDRDSPPDSK-IVVNLTLHLRHAN 228
+LL + T SA S S +D L+ YD P+ K VN+T ++ +
Sbjct: 21 LLLSLVATKETDSARSRSAPMSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINS 80
Query: 229 IRE-SESTVRIQADLQMLQNWIDKRLSWNAGEWGCSTWLVSS-ERLWGPDVVLLNAAATT 402
+E+T+ + ++ + Q W D RL+++ S + +W PD+ N
Sbjct: 81 FGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGAN 140
Query: 403 AGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 573
+ R+ NG+V + RL ++ M L N+P D+QTC + S + +++
Sbjct: 141 FHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFPMDVQTCIMQLESFGYTMNDLI 200
Query: 574 F 576
F
Sbjct: 201 F 201
>AF017724-1|AAC39919.1| 465|Homo sapiens glycine receptor alpha 3
subunit protein.
Length = 465
Score = 44.0 bits (99), Expect = 7e-04
Identities = 44/181 (24%), Positives = 79/181 (43%), Gaps = 9/181 (4%)
Frame = +1
Query: 61 ILLPFLLTCAIASAAECENATSLSLMIDSLLAT---YDRDSPPDSK-IVVNLTLHLRHAN 228
+LL + T SA S S +D L+ YD P+ K VN+T ++ +
Sbjct: 21 LLLSLVATKETDSARSRSAPMSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINS 80
Query: 229 IRE-SESTVRIQADLQMLQNWIDKRLSWNAGEWGCSTWLVSS-ERLWGPDVVLLNAAATT 402
+E+T+ + ++ + Q W D RL+++ S + +W PD+ N
Sbjct: 81 FGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGAN 140
Query: 403 AGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 573
+ R+ NG+V + RL ++ M L N+P D+QTC + S + +++
Sbjct: 141 FHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFPMDVQTCIMQLESFGYTMNDLI 200
Query: 574 F 576
F
Sbjct: 201 F 201
>Y07637-1|CAA68914.1| 505|Homo sapiens putative GABA-gated chloride
channel protein.
Length = 505
Score = 43.6 bits (98), Expect = 0.001
Identities = 41/174 (23%), Positives = 76/174 (43%), Gaps = 10/174 (5%)
Frame = +1
Query: 130 SLMIDSLLATYDRDSPPD-----SKIVVNLTLH-LRHANIRESESTVRIQADLQMLQNWI 291
S +++++L+ YD P + + V + ++ L +I + E T+ D+ Q W
Sbjct: 72 SRILNTILSNYDHKLRPGIGEKPTVVTVEIAVNSLGPLSILDMEYTI----DIIFSQTWY 127
Query: 292 DKRLSWN-AGEWGCSTWLVSSERLWGPDVVLLNAAATTAGDYAL---RARVSNNGSVSWI 459
D+RL +N E V S+ LW PD N+ T + + R+ +G V +
Sbjct: 128 DERLCYNDTFESLVLNGNVVSQ-LWIPDTFFRNSKRTHEHEITMPNQMVRIYKDGKVLYT 186
Query: 460 KRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDKRIYSMFESGAW 621
R+ I S+ + +P D +C F S + +EM + + + E +W
Sbjct: 187 IRMTIDAGCSLHMLRFPMDSHSCPLSFSSFSYPENEMIYKWENFKLEINEKNSW 240
>U66661-1|AAB49284.1| 506|Homo sapiens GABA-A receptor epsilon
subunit protein.
Length = 506
Score = 43.6 bits (98), Expect = 0.001
Identities = 41/174 (23%), Positives = 76/174 (43%), Gaps = 10/174 (5%)
Frame = +1
Query: 130 SLMIDSLLATYDRDSPPD-----SKIVVNLTLH-LRHANIRESESTVRIQADLQMLQNWI 291
S +++++L+ YD P + + V + ++ L +I + E T+ D+ Q W
Sbjct: 72 SRILNTILSNYDHKLRPGIGEKPTVVTVEIAVNSLGPLSILDMEYTI----DIIFSQTWY 127
Query: 292 DKRLSWN-AGEWGCSTWLVSSERLWGPDVVLLNAAATTAGDYAL---RARVSNNGSVSWI 459
D+RL +N E V S+ LW PD N+ T + + R+ +G V +
Sbjct: 128 DERLCYNDTFESLVLNGNVVSQ-LWIPDTFFRNSKRTHEHEITMPNQMVRIYKDGKVLYT 186
Query: 460 KRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDKRIYSMFESGAW 621
R+ I S+ + +P D +C F S + +EM + + + E +W
Sbjct: 187 IRMTIDAGCSLHMLRFPMDSHSCPLSFSSFSYPENEMIYKWENFKLEINEKNSW 240
>BC059376-1|AAH59376.1| 365|Homo sapiens GABRE protein protein.
Length = 365
Score = 43.6 bits (98), Expect = 0.001
Identities = 41/174 (23%), Positives = 76/174 (43%), Gaps = 10/174 (5%)
Frame = +1
Query: 130 SLMIDSLLATYDRDSPPD-----SKIVVNLTLH-LRHANIRESESTVRIQADLQMLQNWI 291
S +++++L+ YD P + + V + ++ L +I + E T+ D+ Q W
Sbjct: 72 SRILNTILSNYDHKLRPGIGEKPTVVTVEIAVNSLGPLSILDMEYTI----DIIFSQTWY 127
Query: 292 DKRLSWN-AGEWGCSTWLVSSERLWGPDVVLLNAAATTAGDYAL---RARVSNNGSVSWI 459
D+RL +N E V S+ LW PD N+ T + + R+ +G V +
Sbjct: 128 DERLCYNDTFESLVLNGNVVSQ-LWIPDTFFRNSKRTHEHEITMPNQMVRIYKDGKVLYT 186
Query: 460 KRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDKRIYSMFESGAW 621
R+ I S+ + +P D +C F S + +EM + + + E +W
Sbjct: 187 IRMTIDAGCSLHMLRFPMDSHSCPLSFSSFSYPENEMIYKWENFKLEINEKNSW 240
>BC047108-1|AAH47108.1| 365|Homo sapiens GABRE protein protein.
Length = 365
Score = 43.6 bits (98), Expect = 0.001
Identities = 41/174 (23%), Positives = 76/174 (43%), Gaps = 10/174 (5%)
Frame = +1
Query: 130 SLMIDSLLATYDRDSPPD-----SKIVVNLTLH-LRHANIRESESTVRIQADLQMLQNWI 291
S +++++L+ YD P + + V + ++ L +I + E T+ D+ Q W
Sbjct: 72 SRILNTILSNYDHKLRPGIGEKPTVVTVEIAVNSLGPLSILDMEYTI----DIIFSQTWY 127
Query: 292 DKRLSWN-AGEWGCSTWLVSSERLWGPDVVLLNAAATTAGDYAL---RARVSNNGSVSWI 459
D+RL +N E V S+ LW PD N+ T + + R+ +G V +
Sbjct: 128 DERLCYNDTFESLVLNGNVVSQ-LWIPDTFFRNSKRTHEHEITMPNQMVRIYKDGKVLYT 186
Query: 460 KRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDKRIYSMFESGAW 621
R+ I S+ + +P D +C F S + +EM + + + E +W
Sbjct: 187 IRMTIDAGCSLHMLRFPMDSHSCPLSFSSFSYPENEMIYKWENFKLEINEKNSW 240
>BC026337-1|AAH26337.1| 365|Homo sapiens GABRE protein protein.
Length = 365
Score = 43.6 bits (98), Expect = 0.001
Identities = 41/174 (23%), Positives = 76/174 (43%), Gaps = 10/174 (5%)
Frame = +1
Query: 130 SLMIDSLLATYDRDSPPD-----SKIVVNLTLH-LRHANIRESESTVRIQADLQMLQNWI 291
S +++++L+ YD P + + V + ++ L +I + E T+ D+ Q W
Sbjct: 72 SRILNTILSNYDHKLRPGIGEKPTVVTVEIAVNSLGPLSILDMEYTI----DIIFSQTWY 127
Query: 292 DKRLSWN-AGEWGCSTWLVSSERLWGPDVVLLNAAATTAGDYAL---RARVSNNGSVSWI 459
D+RL +N E V S+ LW PD N+ T + + R+ +G V +
Sbjct: 128 DERLCYNDTFESLVLNGNVVSQ-LWIPDTFFRNSKRTHEHEITMPNQMVRIYKDGKVLYT 186
Query: 460 KRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDKRIYSMFESGAW 621
R+ I S+ + +P D +C F S + +EM + + + E +W
Sbjct: 187 IRMTIDAGCSLHMLRFPMDSHSCPLSFSSFSYPENEMIYKWENFKLEINEKNSW 240
>Z93848-1|CAI41994.1| 376|Homo sapiens glycine receptor, alpha 4
protein.
Length = 376
Score = 40.7 bits (91), Expect = 0.007
Identities = 29/117 (24%), Positives = 52/117 (44%), Gaps = 4/117 (3%)
Frame = +1
Query: 238 SESTVRIQADLQMLQNWIDKRLSWNAGEWGCSTWLVSS-ERLWGPDVVLLNAAATTAGDY 414
+++T+ + ++ + Q W D RLS+ S + +W PD+ N +
Sbjct: 45 TKTTMDYRVNVFLRQQWNDPRLSYREYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEV 104
Query: 415 ALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDF 576
R+ NG+V + RL + M L N+P D+QTCT + S + ++ F
Sbjct: 105 TTDNKLLRIFKNGNVLYSIRLTLILSCLMDLKNFPMDIQTCTMQLESFGYTMKDLVF 161
>BC114967-1|AAI14968.1| 366|Homo sapiens GLRA1 protein protein.
Length = 366
Score = 40.7 bits (91), Expect = 0.007
Identities = 27/110 (24%), Positives = 50/110 (45%), Gaps = 4/110 (3%)
Frame = +1
Query: 259 QADLQMLQNWIDKRLSWNAGEWGCSTWLVSS-ERLWGPDVVLLNAAATTAGDYALR---A 426
+ ++ + Q W D RL++N S + +W PD+ N +
Sbjct: 4 RVNIFLRQQWNDPRLAYNEYPDDSLDLDPSMLDSIWKPDLFFANEKGAHFHEITTDNKLL 63
Query: 427 RVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDF 576
R+S NG+V + R+ ++ M L N+P D+QTC + S + +++ F
Sbjct: 64 RISRNGNVLYSIRITLTLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIF 113
>BC096291-1|AAH96291.1| 556|Homo sapiens CHRNA4 protein protein.
Length = 556
Score = 40.7 bits (91), Expect = 0.007
Identities = 24/79 (30%), Positives = 41/79 (51%), Gaps = 7/79 (8%)
Frame = +1
Query: 406 GDYAL----RARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 573
GD+A+ +A + ++G V W + S+ + +P D Q CT KFGS ++ ++D
Sbjct: 60 GDFAVTHLTKAHLFHDGRVQWTPPAIYKSSCSIDVTFFPFDQQNCTMKFGSWTYDKAKID 119
Query: 574 FV-IDKRI--YSMFESGAW 621
V + R+ +ESG W
Sbjct: 120 LVNMHSRVDQLDFWESGEW 138
>AL049610-1|CAI42158.1| 376|Homo sapiens glycine receptor, alpha 4
protein.
Length = 376
Score = 40.7 bits (91), Expect = 0.007
Identities = 29/117 (24%), Positives = 52/117 (44%), Gaps = 4/117 (3%)
Frame = +1
Query: 238 SESTVRIQADLQMLQNWIDKRLSWNAGEWGCSTWLVSS-ERLWGPDVVLLNAAATTAGDY 414
+++T+ + ++ + Q W D RLS+ S + +W PD+ N +
Sbjct: 45 TKTTMDYRVNVFLRQQWNDPRLSYREYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEV 104
Query: 415 ALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDF 576
R+ NG+V + RL + M L N+P D+QTCT + S + ++ F
Sbjct: 105 TTDNKLLRIFKNGNVLYSIRLTLILSCLMDLKNFPMDIQTCTMQLESFGYTMKDLVF 161
>AB209359-1|BAD92596.1| 533|Homo sapiens cholinergic receptor,
nicotinic, alpha polypeptide 4 precursor variant
protein.
Length = 533
Score = 40.7 bits (91), Expect = 0.007
Identities = 24/79 (30%), Positives = 41/79 (51%), Gaps = 7/79 (8%)
Frame = +1
Query: 406 GDYAL----RARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 573
GD+A+ +A + ++G V W + S+ + +P D Q CT KFGS ++ ++D
Sbjct: 37 GDFAVTHLTKAHLFHDGRVQWTPPAIYKSSCSIDVTFFPFDQQNCTMKFGSWTYDKAKID 96
Query: 574 FV-IDKRI--YSMFESGAW 621
V + R+ +ESG W
Sbjct: 97 LVNMHSRVDQLDFWESGEW 115
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 120,708,726
Number of Sequences: 237096
Number of extensions: 2819758
Number of successful extensions: 6892
Number of sequences better than 10.0: 186
Number of HSP's better than 10.0 without gapping: 6154
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 6718
length of database: 76,859,062
effective HSP length: 89
effective length of database: 55,757,518
effective search space used: 11095746082
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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