Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BmNP04_FL5_H04
(815 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
X02160-1|CAA26096.1| 1370|Homo sapiens protein ( Human mRNA for ... 158 2e-38
M32972-1|AAA59452.1| 1382|Homo sapiens insulin receptor protein. 158 2e-38
M10051-1|AAA59174.1| 1382|Homo sapiens INSR protein. 158 2e-38
BC117172-1|AAI17173.1| 1370|Homo sapiens insulin receptor protein. 158 2e-38
BC047591-1|AAH47591.1| 743|Homo sapiens INSR protein protein. 157 6e-38
EF207604-1|ABP68900.1| 179|Homo sapiens insulin receptor protein. 144 3e-34
DQ333196-1|ABC46553.1| 179|Homo sapiens insulin receptor protein. 144 3e-34
AL158169-3|CAH70009.1| 1297|Homo sapiens insulin receptor-relate... 143 6e-34
J05046-1|AAC31759.1| 1268|Homo sapiens insulin receptor-related ... 139 1e-32
X04434-1|CAA28030.1| 1367|Homo sapiens IGF-I receptor protein. 138 2e-32
BC113612-1|AAI13613.1| 1367|Homo sapiens insulin-like growth fac... 138 2e-32
BC113610-1|AAI13611.1| 1367|Homo sapiens insulin-like growth fac... 138 2e-32
AY332722-1|AAP81165.1| 1367|Homo sapiens insulin-like growth fac... 138 2e-32
EF207606-1|ABP68902.1| 167|Homo sapiens insulin receptor protein. 133 8e-31
EF207605-1|ABP68901.1| 167|Homo sapiens insulin receptor protein. 133 8e-31
M34309-1|AAA35979.1| 1342|Homo sapiens protein ( Human epidermal... 70 1e-11
M29366-1|AAA35790.1| 1342|Homo sapiens protein ( Human epidermal... 70 1e-11
BT007226-1|AAP35890.1| 331|Homo sapiens v-erb-b2 erythroblastic... 70 1e-11
BC082992-1|AAH82992.1| 1342|Homo sapiens v-erb-b2 erythroblastic... 70 1e-11
BC002706-1|AAH02706.1| 331|Homo sapiens ERBB3 protein protein. 70 1e-11
L07868-1|AAB59446.1| 1308|Homo sapiens receptor tyrosine kinase ... 66 1e-10
BC112199-1|AAI12200.1| 1308|Homo sapiens v-erb-a erythroblastic ... 66 1e-10
X03363-1|CAA27060.1| 1255|Homo sapiens protein ( Human c-erb-B-2... 63 1e-09
M16792-1|AAA58637.1| 191|Homo sapiens HER-2/neu protein. 63 1e-09
M11730-1|AAA75493.1| 1255|Homo sapiens protein ( Human tyrosine ... 63 1e-09
AY208911-1|AAO18082.1| 1255|Homo sapiens v-erb-b2 erythroblastic... 63 1e-09
AF177761-1|AAD56009.2| 419|Homo sapiens herstatin protein. 63 1e-09
X00663-1|CAA25282.1| 800|Homo sapiens protein ( Human mRNA frag... 55 4e-07
X00588-1|CAA25240.1| 1210|Homo sapiens epidermal growth factor r... 55 4e-07
K03193-1|AAA52371.1| 657|Homo sapiens EGFR protein. 55 4e-07
BC128419-1|AAI28420.1| 388|Homo sapiens EGFR protein protein. 55 4e-07
BC118665-1|AAI18666.1| 464|Homo sapiens EGFR protein protein. 55 4e-07
BC094761-1|AAH94761.1| 1091|Homo sapiens EGFR protein protein. 55 4e-07
AY698023-1|AAT97978.1| 645|Homo sapiens epidermal growth factor... 55 4e-07
AY588246-1|AAS83109.1| 1210|Homo sapiens epidermal growth factor... 55 4e-07
AY550966-1|AAT52212.1| 1210|Homo sapiens cell growth inhibiting ... 55 4e-07
AF288738-4|AAG35790.1| 628|Homo sapiens truncated epidermal gro... 55 4e-07
AF288738-3|AAG35786.1| 705|Homo sapiens p110 epidermal growth f... 55 4e-07
AF288738-2|AAG35788.1| 657|Homo sapiens A431-specific p115 epid... 55 4e-07
AF288738-1|AAG35789.1| 1210|Homo sapiens p170 epidermal growth f... 55 4e-07
AF125253-1|AAG43240.1| 705|Homo sapiens truncated epidermal gro... 55 4e-07
AB209442-1|BAD92679.1| 1081|Homo sapiens epidermal growth factor... 55 4e-07
AC105921-1|AAY24303.1| 552|Homo sapiens unknown protein. 54 8e-07
U95089-1|AAB53063.1| 405|Homo sapiens truncated epidermal growt... 48 5e-05
U48722-1|AAC50802.1| 405|Homo sapiens epidermal growth factor r... 48 5e-05
AY698024-1|AAT97979.1| 405|Homo sapiens epidermal growth factor... 48 5e-05
AF288738-5|AAG35787.1| 405|Homo sapiens p60 epidermal growth fa... 48 5e-05
AB209697-1|BAD92934.1| 892|Homo sapiens v-erb-a erythroblastic ... 47 7e-05
S61953-1|AAB26935.1| 183|Homo sapiens receptor tyrosine kinase ... 43 0.001
U48727-1|AAC50799.1| 66|Homo sapiens epidermal growth factor r... 41 0.006
AC093823-1|AAY14899.1| 62|Homo sapiens unknown protein. 33 0.93
AL009182-2|CAI22773.1| 639|Homo sapiens chromosome 1 open readi... 31 5.0
AF503509-1|AAQ07593.1| 639|Homo sapiens C1orf32 putative protei... 31 5.0
D88667-1|BAA13673.1| 423|Homo sapiens cerebroside sulfotransfer... 31 6.6
CR456350-1|CAG30236.1| 423|Homo sapiens Em:AC005006.2 protein. 31 6.6
BC019077-1|AAH19077.1| 423|Homo sapiens galactose-3-O-sulfotran... 31 6.6
BC014649-1|AAH14649.1| 423|Homo sapiens GAL3ST1 protein protein. 31 6.6
AB029901-1|BAA89503.1| 423|Homo sapiens cerebroside sulfotransf... 31 6.6
>X02160-1|CAA26096.1| 1370|Homo sapiens protein ( Human mRNA for
insulin receptor precursor. ).
Length = 1370
Score = 158 bits (384), Expect = 2e-38
Identities = 80/156 (51%), Positives = 105/156 (67%), Gaps = 2/156 (1%)
Frame = +3
Query: 294 AVACALLIACARTYAGT--EVVPARGVCPSMDLRNNPDQIRRLEGCRVIEGQLSIVLMER 467
A A LL+A A G + P VCP MD+RNN ++ LE C VIEG L I+LM +
Sbjct: 9 AAAAPLLVAVAALLLGAAGHLYPGE-VCPGMDIRNNLTRLHELENCSVIEGHLQILLMFK 67
Query: 468 ATNKIFDNMSFPQLREVTGYILIYRTKGLRNLGDLFPNLTVVRGMQLFKDFALVIFDNEH 647
+ F ++SFP+L +T Y+L++R GL +L DLFPNLTV+RG +LF ++ALVIF+ H
Sbjct: 68 TRPEDFRDLSFPKLIMITDYLLLFRVYGLESLKDLFPNLTVIRGSRLFFNYALVIFEMVH 127
Query: 648 LEALGLNSLMKIERGGVRIQHNDRLCYTNTIDWSRI 755
L+ LGL +LM I RG VRI+ N+ LCY TIDWSRI
Sbjct: 128 LKELGLYNLMNITRGSVRIEKNNELCYLATIDWSRI 163
>M32972-1|AAA59452.1| 1382|Homo sapiens insulin receptor protein.
Length = 1382
Score = 158 bits (384), Expect = 2e-38
Identities = 80/156 (51%), Positives = 105/156 (67%), Gaps = 2/156 (1%)
Frame = +3
Query: 294 AVACALLIACARTYAGT--EVVPARGVCPSMDLRNNPDQIRRLEGCRVIEGQLSIVLMER 467
A A LL+A A G + P VCP MD+RNN ++ LE C VIEG L I+LM +
Sbjct: 9 AAAAPLLVAVAALLLGAAGHLYPGE-VCPGMDIRNNLTRLHELENCSVIEGHLQILLMFK 67
Query: 468 ATNKIFDNMSFPQLREVTGYILIYRTKGLRNLGDLFPNLTVVRGMQLFKDFALVIFDNEH 647
+ F ++SFP+L +T Y+L++R GL +L DLFPNLTV+RG +LF ++ALVIF+ H
Sbjct: 68 TRPEDFRDLSFPKLIMITDYLLLFRVYGLESLKDLFPNLTVIRGSRLFFNYALVIFEMVH 127
Query: 648 LEALGLNSLMKIERGGVRIQHNDRLCYTNTIDWSRI 755
L+ LGL +LM I RG VRI+ N+ LCY TIDWSRI
Sbjct: 128 LKELGLYNLMNITRGSVRIEKNNELCYLATIDWSRI 163
>M10051-1|AAA59174.1| 1382|Homo sapiens INSR protein.
Length = 1382
Score = 158 bits (384), Expect = 2e-38
Identities = 80/156 (51%), Positives = 105/156 (67%), Gaps = 2/156 (1%)
Frame = +3
Query: 294 AVACALLIACARTYAGT--EVVPARGVCPSMDLRNNPDQIRRLEGCRVIEGQLSIVLMER 467
A A LL+A A G + P VCP MD+RNN ++ LE C VIEG L I+LM +
Sbjct: 9 AAAAPLLVAVAALLLGAAGHLYPGE-VCPGMDIRNNLTRLHELENCSVIEGHLQILLMFK 67
Query: 468 ATNKIFDNMSFPQLREVTGYILIYRTKGLRNLGDLFPNLTVVRGMQLFKDFALVIFDNEH 647
+ F ++SFP+L +T Y+L++R GL +L DLFPNLTV+RG +LF ++ALVIF+ H
Sbjct: 68 TRPEDFRDLSFPKLIMITDYLLLFRVYGLESLKDLFPNLTVIRGSRLFFNYALVIFEMVH 127
Query: 648 LEALGLNSLMKIERGGVRIQHNDRLCYTNTIDWSRI 755
L+ LGL +LM I RG VRI+ N+ LCY TIDWSRI
Sbjct: 128 LKELGLYNLMNITRGSVRIEKNNELCYLATIDWSRI 163
>BC117172-1|AAI17173.1| 1370|Homo sapiens insulin receptor protein.
Length = 1370
Score = 158 bits (384), Expect = 2e-38
Identities = 80/156 (51%), Positives = 105/156 (67%), Gaps = 2/156 (1%)
Frame = +3
Query: 294 AVACALLIACARTYAGT--EVVPARGVCPSMDLRNNPDQIRRLEGCRVIEGQLSIVLMER 467
A A LL+A A G + P VCP MD+RNN ++ LE C VIEG L I+LM +
Sbjct: 9 AAAAPLLVAVAALLLGAAGHLYPGE-VCPGMDIRNNLTRLHELENCSVIEGHLQILLMFK 67
Query: 468 ATNKIFDNMSFPQLREVTGYILIYRTKGLRNLGDLFPNLTVVRGMQLFKDFALVIFDNEH 647
+ F ++SFP+L +T Y+L++R GL +L DLFPNLTV+RG +LF ++ALVIF+ H
Sbjct: 68 TRPEDFRDLSFPKLIMITDYLLLFRVYGLESLKDLFPNLTVIRGSRLFFNYALVIFEMVH 127
Query: 648 LEALGLNSLMKIERGGVRIQHNDRLCYTNTIDWSRI 755
L+ LGL +LM I RG VRI+ N+ LCY TIDWSRI
Sbjct: 128 LKELGLYNLMNITRGSVRIEKNNELCYLATIDWSRI 163
>BC047591-1|AAH47591.1| 743|Homo sapiens INSR protein protein.
Length = 743
Score = 157 bits (380), Expect = 6e-38
Identities = 80/154 (51%), Positives = 103/154 (66%)
Frame = +3
Query: 294 AVACALLIACARTYAGTEVVPARGVCPSMDLRNNPDQIRRLEGCRVIEGQLSIVLMERAT 473
AVA LL A Y G VCP MD+RNN ++ LE C VIEG L I+LM +
Sbjct: 8 AVAALLLGAAGHLYPGE-------VCPGMDIRNNLTRLHELENCSVIEGHLQILLMFKTR 60
Query: 474 NKIFDNMSFPQLREVTGYILIYRTKGLRNLGDLFPNLTVVRGMQLFKDFALVIFDNEHLE 653
+ F ++SFP+L +T Y+L++R GL +L DLFPNLTV+RG +LF ++ALVIF+ HL+
Sbjct: 61 PEDFRDLSFPKLIMITDYLLLFRVYGLESLKDLFPNLTVIRGSRLFFNYALVIFEMVHLK 120
Query: 654 ALGLNSLMKIERGGVRIQHNDRLCYTNTIDWSRI 755
LGL +LM I RG VRI+ N+ LCY TIDWSRI
Sbjct: 121 ELGLYNLMNITRGSVRIEKNNELCYLATIDWSRI 154
>EF207604-1|ABP68900.1| 179|Homo sapiens insulin receptor protein.
Length = 179
Score = 144 bits (349), Expect = 3e-34
Identities = 68/125 (54%), Positives = 91/125 (72%)
Frame = +3
Query: 381 DLRNNPDQIRRLEGCRVIEGQLSIVLMERATNKIFDNMSFPQLREVTGYILIYRTKGLRN 560
D+RNN ++ LE C VIEG L I+LM + + F ++SFP+L +T Y+L++R GL +
Sbjct: 1 DIRNNLTRLHELENCSVIEGHLQILLMFKTRPEDFRDLSFPKLIMITDYLLLFRVYGLES 60
Query: 561 LGDLFPNLTVVRGMQLFKDFALVIFDNEHLEALGLNSLMKIERGGVRIQHNDRLCYTNTI 740
L DLFPNLTV+RG +LF ++ALVIF+ HL+ LGL +LM I RG VRI+ N+ LCY TI
Sbjct: 61 LKDLFPNLTVIRGSRLFFNYALVIFEMVHLKELGLYNLMNITRGSVRIEKNNELCYLATI 120
Query: 741 DWSRI 755
DWSRI
Sbjct: 121 DWSRI 125
>DQ333196-1|ABC46553.1| 179|Homo sapiens insulin receptor protein.
Length = 179
Score = 144 bits (349), Expect = 3e-34
Identities = 68/125 (54%), Positives = 91/125 (72%)
Frame = +3
Query: 381 DLRNNPDQIRRLEGCRVIEGQLSIVLMERATNKIFDNMSFPQLREVTGYILIYRTKGLRN 560
D+RNN ++ LE C VIEG L I+LM + + F ++SFP+L +T Y+L++R GL +
Sbjct: 1 DIRNNLTRLHELENCSVIEGHLQILLMFKTRPEDFRDLSFPKLIMITDYLLLFRVYGLES 60
Query: 561 LGDLFPNLTVVRGMQLFKDFALVIFDNEHLEALGLNSLMKIERGGVRIQHNDRLCYTNTI 740
L DLFPNLTV+RG +LF ++ALVIF+ HL+ LGL +LM I RG VRI+ N+ LCY TI
Sbjct: 61 LKDLFPNLTVIRGSRLFFNYALVIFEMVHLKELGLYNLMNITRGSVRIEKNNELCYLATI 120
Query: 741 DWSRI 755
DWSRI
Sbjct: 121 DWSRI 125
>AL158169-3|CAH70009.1| 1297|Homo sapiens insulin receptor-related
receptor protein.
Length = 1297
Score = 143 bits (347), Expect = 6e-34
Identities = 70/153 (45%), Positives = 101/153 (66%)
Frame = +3
Query: 288 WPAVACALLIACARTYAGTEVVPARGVCPSMDLRNNPDQIRRLEGCRVIEGQLSIVLMER 467
WP AC +I + + G + V VCPS+D+R+ ++R+LE C V+EG L I+LM
Sbjct: 7 WPWGACLPVIFLSLGF-GLDTVE---VCPSLDIRSEVAELRQLENCSVVEGHLQILLMFT 62
Query: 468 ATNKIFDNMSFPQLREVTGYILIYRTKGLRNLGDLFPNLTVVRGMQLFKDFALVIFDNEH 647
AT + F +SFP+L +VT Y+L++R GL +L DLFPNL V+RG +LF +ALVIF+ H
Sbjct: 63 ATGEDFRGLSFPRLTQVTDYLLLFRVYGLESLRDLFPNLAVIRGTRLFLGYALVIFEMPH 122
Query: 648 LEALGLNSLMKIERGGVRIQHNDRLCYTNTIDW 746
L + L +L + RG VR++ N LC+ +TIDW
Sbjct: 123 LRDVALPALGAVLRGAVRVEKNQELCHLSTIDW 155
>J05046-1|AAC31759.1| 1268|Homo sapiens insulin receptor-related
receptor protein.
Length = 1268
Score = 139 bits (336), Expect = 1e-32
Identities = 62/126 (49%), Positives = 89/126 (70%)
Frame = +3
Query: 369 CPSMDLRNNPDQIRRLEGCRVIEGQLSIVLMERATNKIFDNMSFPQLREVTGYILIYRTK 548
CPS+D+R+ ++R+LE C V+EG L I+LM AT + F +SFP+L +VT Y+L++R
Sbjct: 1 CPSLDIRSEVAELRQLENCSVVEGHLQILLMFTATGEDFRGLSFPRLTQVTDYLLLFRVY 60
Query: 549 GLRNLGDLFPNLTVVRGMQLFKDFALVIFDNEHLEALGLNSLMKIERGGVRIQHNDRLCY 728
GL +L DLFPNL V+RG +LF +ALVIF+ HL + L +L + RG VR++ N LC+
Sbjct: 61 GLESLRDLFPNLAVIRGTRLFLGYALVIFEMPHLRDVALPALGAVLRGAVRVEKNQELCH 120
Query: 729 TNTIDW 746
+TIDW
Sbjct: 121 LSTIDW 126
>X04434-1|CAA28030.1| 1367|Homo sapiens IGF-I receptor protein.
Length = 1367
Score = 138 bits (334), Expect = 2e-32
Identities = 67/142 (47%), Positives = 99/142 (69%), Gaps = 2/142 (1%)
Frame = +3
Query: 336 AGTEVVPARG-VC-PSMDLRNNPDQIRRLEGCRVIEGQLSIVLMERATNKIFDNMSFPQL 509
A + P G +C P +D+RN+ Q++RLE C VIEG L I+L+ +A + + + FP+L
Sbjct: 21 AALSLWPTSGEICGPGIDIRNDYQQLKRLENCTVIEGYLHILLISKAED--YRSYRFPKL 78
Query: 510 REVTGYILIYRTKGLRNLGDLFPNLTVVRGMQLFKDFALVIFDNEHLEALGLNSLMKIER 689
+T Y+L++R GL +LGDLFPNLTV+RG +LF ++ALVIF+ +L+ +GL +L I R
Sbjct: 79 TVITEYLLLFRVAGLESLGDLFPNLTVIRGWKLFYNYALVIFEMTNLKDIGLYNLRNITR 138
Query: 690 GGVRIQHNDRLCYTNTIDWSRI 755
G +RI+ N LCY +T+DWS I
Sbjct: 139 GAIRIEKNADLCYLSTVDWSLI 160
Score = 40.3 bits (90), Expect = 0.008
Identities = 37/136 (27%), Positives = 66/136 (48%), Gaps = 11/136 (8%)
Frame = +3
Query: 351 VPARGVCPSMDLRNNP----DQI---RRLEGCRVIEGQLSIVLMERATNKIFDNMSFPQL 509
+P G CP + D + + L+GC + +G L ++ + R N + +F L
Sbjct: 322 IPCEGPCPKVCEEEKKTKTIDSVTSAQMLQGCTIFKGNL-LINIRRGNNIASELENFMGL 380
Query: 510 REV-TGYILIYRTKGLRNLGDLFPNLTVVRGM-QLFKDFALVIFDNEHLEAL--GLNSLM 677
EV TGY+ I + L +L L NL ++ G QL +++ + DN++L+ L + +
Sbjct: 381 IEVVTGYVKIRHSHALVSLSFL-KNLRLILGEEQLEGNYSFYVLDNQNLQQLWDWDHRNL 439
Query: 678 KIERGGVRIQHNDRLC 725
I+ G + N +LC
Sbjct: 440 TIKAGKMYFAFNPKLC 455
>BC113612-1|AAI13613.1| 1367|Homo sapiens insulin-like growth factor
1 receptor protein.
Length = 1367
Score = 138 bits (334), Expect = 2e-32
Identities = 67/142 (47%), Positives = 99/142 (69%), Gaps = 2/142 (1%)
Frame = +3
Query: 336 AGTEVVPARG-VC-PSMDLRNNPDQIRRLEGCRVIEGQLSIVLMERATNKIFDNMSFPQL 509
A + P G +C P +D+RN+ Q++RLE C VIEG L I+L+ +A + + + FP+L
Sbjct: 21 AALSLWPTSGEICGPGIDIRNDYQQLKRLENCTVIEGYLHILLISKAED--YRSYRFPKL 78
Query: 510 REVTGYILIYRTKGLRNLGDLFPNLTVVRGMQLFKDFALVIFDNEHLEALGLNSLMKIER 689
+T Y+L++R GL +LGDLFPNLTV+RG +LF ++ALVIF+ +L+ +GL +L I R
Sbjct: 79 TVITEYLLLFRVAGLESLGDLFPNLTVIRGWKLFYNYALVIFEMTNLKDIGLYNLRNITR 138
Query: 690 GGVRIQHNDRLCYTNTIDWSRI 755
G +RI+ N LCY +T+DWS I
Sbjct: 139 GAIRIEKNADLCYLSTVDWSLI 160
Score = 40.3 bits (90), Expect = 0.008
Identities = 37/136 (27%), Positives = 66/136 (48%), Gaps = 11/136 (8%)
Frame = +3
Query: 351 VPARGVCPSMDLRNNP----DQI---RRLEGCRVIEGQLSIVLMERATNKIFDNMSFPQL 509
+P G CP + D + + L+GC + +G L ++ + R N + +F L
Sbjct: 322 IPCEGPCPKVCEEEKKTKTIDSVTSAQMLQGCTIFKGNL-LINIRRGNNIASELENFMGL 380
Query: 510 REV-TGYILIYRTKGLRNLGDLFPNLTVVRGM-QLFKDFALVIFDNEHLEAL--GLNSLM 677
EV TGY+ I + L +L L NL ++ G QL +++ + DN++L+ L + +
Sbjct: 381 IEVVTGYVKIRHSHALVSLSFL-KNLRLILGEEQLEGNYSFYVLDNQNLQQLWDWDHRNL 439
Query: 678 KIERGGVRIQHNDRLC 725
I+ G + N +LC
Sbjct: 440 TIKAGKMYFAFNPKLC 455
>BC113610-1|AAI13611.1| 1367|Homo sapiens insulin-like growth factor
1 receptor protein.
Length = 1367
Score = 138 bits (334), Expect = 2e-32
Identities = 67/142 (47%), Positives = 99/142 (69%), Gaps = 2/142 (1%)
Frame = +3
Query: 336 AGTEVVPARG-VC-PSMDLRNNPDQIRRLEGCRVIEGQLSIVLMERATNKIFDNMSFPQL 509
A + P G +C P +D+RN+ Q++RLE C VIEG L I+L+ +A + + + FP+L
Sbjct: 21 AALSLWPTSGEICGPGIDIRNDYQQLKRLENCTVIEGYLHILLISKAED--YRSYRFPKL 78
Query: 510 REVTGYILIYRTKGLRNLGDLFPNLTVVRGMQLFKDFALVIFDNEHLEALGLNSLMKIER 689
+T Y+L++R GL +LGDLFPNLTV+RG +LF ++ALVIF+ +L+ +GL +L I R
Sbjct: 79 TVITEYLLLFRVAGLESLGDLFPNLTVIRGWKLFYNYALVIFEMTNLKDIGLYNLRNITR 138
Query: 690 GGVRIQHNDRLCYTNTIDWSRI 755
G +RI+ N LCY +T+DWS I
Sbjct: 139 GAIRIEKNADLCYLSTVDWSLI 160
Score = 40.3 bits (90), Expect = 0.008
Identities = 37/136 (27%), Positives = 66/136 (48%), Gaps = 11/136 (8%)
Frame = +3
Query: 351 VPARGVCPSMDLRNNP----DQI---RRLEGCRVIEGQLSIVLMERATNKIFDNMSFPQL 509
+P G CP + D + + L+GC + +G L ++ + R N + +F L
Sbjct: 322 IPCEGPCPKVCEEEKKTKTIDSVTSAQMLQGCTIFKGNL-LINIRRGNNIASELENFMGL 380
Query: 510 REV-TGYILIYRTKGLRNLGDLFPNLTVVRGM-QLFKDFALVIFDNEHLEAL--GLNSLM 677
EV TGY+ I + L +L L NL ++ G QL +++ + DN++L+ L + +
Sbjct: 381 IEVVTGYVKIRHSHALVSLSFL-KNLRLILGEEQLEGNYSFYVLDNQNLQQLWDWDHRNL 439
Query: 678 KIERGGVRIQHNDRLC 725
I+ G + N +LC
Sbjct: 440 TIKAGKMYFAFNPKLC 455
>AY332722-1|AAP81165.1| 1367|Homo sapiens insulin-like growth factor
1 receptor protein.
Length = 1367
Score = 138 bits (334), Expect = 2e-32
Identities = 67/142 (47%), Positives = 99/142 (69%), Gaps = 2/142 (1%)
Frame = +3
Query: 336 AGTEVVPARG-VC-PSMDLRNNPDQIRRLEGCRVIEGQLSIVLMERATNKIFDNMSFPQL 509
A + P G +C P +D+RN+ Q++RLE C VIEG L I+L+ +A + + + FP+L
Sbjct: 21 AALSLWPTSGEICGPGIDIRNDYQQLKRLENCTVIEGYLHILLISKAED--YRSYRFPKL 78
Query: 510 REVTGYILIYRTKGLRNLGDLFPNLTVVRGMQLFKDFALVIFDNEHLEALGLNSLMKIER 689
+T Y+L++R GL +LGDLFPNLTV+RG +LF ++ALVIF+ +L+ +GL +L I R
Sbjct: 79 TVITEYLLLFRVAGLESLGDLFPNLTVIRGWKLFYNYALVIFEMTNLKDIGLYNLRNITR 138
Query: 690 GGVRIQHNDRLCYTNTIDWSRI 755
G +RI+ N LCY +T+DWS I
Sbjct: 139 GAIRIEKNADLCYLSTVDWSLI 160
Score = 40.3 bits (90), Expect = 0.008
Identities = 37/136 (27%), Positives = 66/136 (48%), Gaps = 11/136 (8%)
Frame = +3
Query: 351 VPARGVCPSMDLRNNP----DQI---RRLEGCRVIEGQLSIVLMERATNKIFDNMSFPQL 509
+P G CP + D + + L+GC + +G L ++ + R N + +F L
Sbjct: 322 IPCEGPCPKVCEEEKKTKTIDSVTSAQMLQGCTIFKGNL-LINIRRGNNIASELENFMGL 380
Query: 510 REV-TGYILIYRTKGLRNLGDLFPNLTVVRGM-QLFKDFALVIFDNEHLEAL--GLNSLM 677
EV TGY+ I + L +L L NL ++ G QL +++ + DN++L+ L + +
Sbjct: 381 IEVVTGYVKIRHSHALVSLSFL-KNLRLILGEEQLEGNYSFYVLDNQNLQQLWDWDHRNL 439
Query: 678 KIERGGVRIQHNDRLC 725
I+ G + N +LC
Sbjct: 440 TIKAGKMYFAFNPKLC 455
>EF207606-1|ABP68902.1| 167|Homo sapiens insulin receptor protein.
Length = 167
Score = 133 bits (321), Expect = 8e-31
Identities = 63/113 (55%), Positives = 83/113 (73%)
Frame = +3
Query: 417 EGCRVIEGQLSIVLMERATNKIFDNMSFPQLREVTGYILIYRTKGLRNLGDLFPNLTVVR 596
E C VIEG L I+LM + + F ++SFP+L +T Y+L++R GL +L DLFPNLTV+R
Sbjct: 1 ENCSVIEGHLQILLMFKTRPEDFRDLSFPKLIMITDYLLLFRVYGLESLKDLFPNLTVIR 60
Query: 597 GMQLFKDFALVIFDNEHLEALGLNSLMKIERGGVRIQHNDRLCYTNTIDWSRI 755
G +LF ++ALVIF+ HL+ LGL +LM I RG VRI+ N+ LCY TIDWSRI
Sbjct: 61 GSRLFFNYALVIFEMVHLKELGLYNLMNITRGSVRIEKNNELCYLATIDWSRI 113
>EF207605-1|ABP68901.1| 167|Homo sapiens insulin receptor protein.
Length = 167
Score = 133 bits (321), Expect = 8e-31
Identities = 63/113 (55%), Positives = 83/113 (73%)
Frame = +3
Query: 417 EGCRVIEGQLSIVLMERATNKIFDNMSFPQLREVTGYILIYRTKGLRNLGDLFPNLTVVR 596
E C VIEG L I+LM + + F ++SFP+L +T Y+L++R GL +L DLFPNLTV+R
Sbjct: 1 ENCSVIEGHLQILLMFKTRPEDFRDLSFPKLIMITDYLLLFRVYGLESLKDLFPNLTVIR 60
Query: 597 GMQLFKDFALVIFDNEHLEALGLNSLMKIERGGVRIQHNDRLCYTNTIDWSRI 755
G +LF ++ALVIF+ HL+ LGL +LM I RG VRI+ N+ LCY TIDWSRI
Sbjct: 61 GSRLFFNYALVIFEMVHLKELGLYNLMNITRGSVRIEKNNELCYLATIDWSRI 113
>M34309-1|AAA35979.1| 1342|Homo sapiens protein ( Human epidermal
growth factor receptor (HER3) mRNA, complete cds. ).
Length = 1342
Score = 69.7 bits (163), Expect = 1e-11
Identities = 61/167 (36%), Positives = 84/167 (50%), Gaps = 18/167 (10%)
Frame = +3
Query: 309 LLIACARTYAGTEVVPARGVCPSM--------DLRNNPDQIRRL-EGCRVIEGQLSIVLM 461
LL + AR G+EV ++ VCP D N + +L E C V+ G L IVL
Sbjct: 12 LLFSLAR---GSEVGNSQAVCPGTLNGLSVTGDAENQYQTLYKLYERCEVVMGNLEIVLT 68
Query: 462 ERATNKIFDNMSFPQ-LREVTGYILIYRTKGLRNLGDL-FPNLTVVRGMQLFKD-FALVI 632
+ +SF Q +REVTGY+L+ + L PNL VVRG Q++ FA+ +
Sbjct: 69 GHNAD-----LSFLQWIREVTGYVLV----AMNEFSTLPLPNLRVVRGTQVYDGKFAIFV 119
Query: 633 FDNEH------LEALGLNSLMKIERGGVRIQHNDRLCYTNTIDWSRI 755
N + L L L L +I GGV I+ ND+LC+ +TIDW I
Sbjct: 120 MLNYNTNSSHALRQLRLTQLTEILSGGVYIEKNDKLCHMDTIDWRDI 166
Score = 60.1 bits (139), Expect = 9e-09
Identities = 29/87 (33%), Positives = 52/87 (59%), Gaps = 1/87 (1%)
Frame = +3
Query: 498 FPQLREVTGYILIYRTKGLRNLGDLFPNLTVVRGMQLF-KDFALVIFDNEHLEALGLNSL 674
F +RE+TGY+ I + +F NLT + G L+ + F+L+I N ++ +LG SL
Sbjct: 387 FRTVREITGYLNIQSWPPHMHNFSVFSNLTTIGGRSLYNRGFSLLIMKNLNVTSLGFRSL 446
Query: 675 MKIERGGVRIQHNDRLCYTNTIDWSRI 755
+I G + I N +LCY ++++W+++
Sbjct: 447 KEISAGRIYISANRQLCYHHSLNWTKV 473
>M29366-1|AAA35790.1| 1342|Homo sapiens protein ( Human epidermal
growth factor receptor (ERBB3) mRNA, complete cds. ).
Length = 1342
Score = 69.7 bits (163), Expect = 1e-11
Identities = 61/167 (36%), Positives = 84/167 (50%), Gaps = 18/167 (10%)
Frame = +3
Query: 309 LLIACARTYAGTEVVPARGVCPSM--------DLRNNPDQIRRL-EGCRVIEGQLSIVLM 461
LL + AR G+EV ++ VCP D N + +L E C V+ G L IVL
Sbjct: 12 LLFSLAR---GSEVGNSQAVCPGTLNGLSVTGDAENQYQTLYKLYERCEVVMGNLEIVLT 68
Query: 462 ERATNKIFDNMSFPQ-LREVTGYILIYRTKGLRNLGDL-FPNLTVVRGMQLFKD-FALVI 632
+ +SF Q +REVTGY+L+ + L PNL VVRG Q++ FA+ +
Sbjct: 69 GHNAD-----LSFLQWIREVTGYVLV----AMNEFSTLPLPNLRVVRGTQVYDGKFAIFV 119
Query: 633 FDNEH------LEALGLNSLMKIERGGVRIQHNDRLCYTNTIDWSRI 755
N + L L L L +I GGV I+ ND+LC+ +TIDW I
Sbjct: 120 MLNYNTNSSHALRQLRLTQLTEILSGGVYIEKNDKLCHMDTIDWRDI 166
Score = 60.1 bits (139), Expect = 9e-09
Identities = 29/87 (33%), Positives = 52/87 (59%), Gaps = 1/87 (1%)
Frame = +3
Query: 498 FPQLREVTGYILIYRTKGLRNLGDLFPNLTVVRGMQLF-KDFALVIFDNEHLEALGLNSL 674
F +RE+TGY+ I + +F NLT + G L+ + F+L+I N ++ +LG SL
Sbjct: 387 FRTVREITGYLNIQSWPPHMHNFSVFSNLTTIGGRSLYNRGFSLLIMKNLNVTSLGFRSL 446
Query: 675 MKIERGGVRIQHNDRLCYTNTIDWSRI 755
+I G + I N +LCY ++++W+++
Sbjct: 447 KEISAGRIYISANRQLCYHHSLNWTKV 473
>BT007226-1|AAP35890.1| 331|Homo sapiens v-erb-b2 erythroblastic
leukemia viral oncogene homolog 3 (avian) protein.
Length = 331
Score = 69.7 bits (163), Expect = 1e-11
Identities = 61/167 (36%), Positives = 84/167 (50%), Gaps = 18/167 (10%)
Frame = +3
Query: 309 LLIACARTYAGTEVVPARGVCPSM--------DLRNNPDQIRRL-EGCRVIEGQLSIVLM 461
LL + AR G+EV ++ VCP D N + +L E C V+ G L IVL
Sbjct: 12 LLFSLAR---GSEVGNSQAVCPGTLNGLSVTGDAENQYQTLYKLYERCEVVMGNLEIVLT 68
Query: 462 ERATNKIFDNMSFPQ-LREVTGYILIYRTKGLRNLGDL-FPNLTVVRGMQLFKD-FALVI 632
+ +SF Q +REVTGY+L+ + L PNL VVRG Q++ FA+ +
Sbjct: 69 GHNAD-----LSFLQWIREVTGYVLV----AMNEFSTLPLPNLRVVRGTQVYDGKFAIFV 119
Query: 633 FDNEH------LEALGLNSLMKIERGGVRIQHNDRLCYTNTIDWSRI 755
N + L L L L +I GGV I+ ND+LC+ +TIDW I
Sbjct: 120 MLNYNTNSSHALRQLRLTQLTEILSGGVYIEKNDKLCHMDTIDWRDI 166
>BC082992-1|AAH82992.1| 1342|Homo sapiens v-erb-b2 erythroblastic
leukemia viral oncogene homolog 3 (avian) protein.
Length = 1342
Score = 69.7 bits (163), Expect = 1e-11
Identities = 61/167 (36%), Positives = 84/167 (50%), Gaps = 18/167 (10%)
Frame = +3
Query: 309 LLIACARTYAGTEVVPARGVCPSM--------DLRNNPDQIRRL-EGCRVIEGQLSIVLM 461
LL + AR G+EV ++ VCP D N + +L E C V+ G L IVL
Sbjct: 12 LLFSLAR---GSEVGNSQAVCPGTLNGLSVTGDAENQYQTLYKLYERCEVVMGNLEIVLT 68
Query: 462 ERATNKIFDNMSFPQ-LREVTGYILIYRTKGLRNLGDL-FPNLTVVRGMQLFKD-FALVI 632
+ +SF Q +REVTGY+L+ + L PNL VVRG Q++ FA+ +
Sbjct: 69 GHNAD-----LSFLQWIREVTGYVLV----AMNEFSTLPLPNLRVVRGTQVYDGKFAIFV 119
Query: 633 FDNEH------LEALGLNSLMKIERGGVRIQHNDRLCYTNTIDWSRI 755
N + L L L L +I GGV I+ ND+LC+ +TIDW I
Sbjct: 120 MLNYNTNSSHALRQLRLTQLTEILSGGVYIEKNDKLCHMDTIDWRDI 166
Score = 60.1 bits (139), Expect = 9e-09
Identities = 29/87 (33%), Positives = 52/87 (59%), Gaps = 1/87 (1%)
Frame = +3
Query: 498 FPQLREVTGYILIYRTKGLRNLGDLFPNLTVVRGMQLF-KDFALVIFDNEHLEALGLNSL 674
F +RE+TGY+ I + +F NLT + G L+ + F+L+I N ++ +LG SL
Sbjct: 387 FRTVREITGYLNIQSWPPHMHNFSVFSNLTTIGGRSLYNRGFSLLIMKNLNVTSLGFRSL 446
Query: 675 MKIERGGVRIQHNDRLCYTNTIDWSRI 755
+I G + I N +LCY ++++W+++
Sbjct: 447 KEISAGRIYISANRQLCYHHSLNWTKV 473
>BC002706-1|AAH02706.1| 331|Homo sapiens ERBB3 protein protein.
Length = 331
Score = 69.7 bits (163), Expect = 1e-11
Identities = 61/167 (36%), Positives = 84/167 (50%), Gaps = 18/167 (10%)
Frame = +3
Query: 309 LLIACARTYAGTEVVPARGVCPSM--------DLRNNPDQIRRL-EGCRVIEGQLSIVLM 461
LL + AR G+EV ++ VCP D N + +L E C V+ G L IVL
Sbjct: 12 LLFSLAR---GSEVGNSQAVCPGTLNGLSVTGDAENQYQTLYKLYERCEVVMGNLEIVLT 68
Query: 462 ERATNKIFDNMSFPQ-LREVTGYILIYRTKGLRNLGDL-FPNLTVVRGMQLFKD-FALVI 632
+ +SF Q +REVTGY+L+ + L PNL VVRG Q++ FA+ +
Sbjct: 69 GHNAD-----LSFLQWIREVTGYVLV----AMNEFSTLPLPNLRVVRGTQVYDGKFAIFV 119
Query: 633 FDNEH------LEALGLNSLMKIERGGVRIQHNDRLCYTNTIDWSRI 755
N + L L L L +I GGV I+ ND+LC+ +TIDW I
Sbjct: 120 MLNYNTNSSHALRQLRLTQLTEILSGGVYIEKNDKLCHMDTIDWRDI 166
>L07868-1|AAB59446.1| 1308|Homo sapiens receptor tyrosine kinase
protein.
Length = 1308
Score = 66.1 bits (154), Expect = 1e-10
Identities = 48/133 (36%), Positives = 68/133 (51%), Gaps = 8/133 (6%)
Frame = +3
Query: 381 DLRNNPDQIRRL-EGCRVIEGQLSIVLMERATNKIFDNMSFPQLREVTGYILIYRTKGLR 557
DL +R+ E C V+ G L I +E + F +REVTGY+L+ + R
Sbjct: 41 DLEQQYRALRKYYENCEVVMGNLEITSIEHNRDLSF----LRSVREVTGYVLVALNQ-FR 95
Query: 558 NLGDLFPNLTVVRGMQLFKD-FALVIFDNEH------LEALGLNSLMKIERGGVRIQHND 716
L NL ++RG +L++D +AL IF N L+ LGL +L +I GGV + N
Sbjct: 96 YLP--LENLRIIRGTKLYEDRYALAIFLNYRKDGNFGLQELGLKNLTEILNGGVYVDQNK 153
Query: 717 RLCYTNTIDWSRI 755
LCY +TI W I
Sbjct: 154 FLCYADTIHWQDI 166
Score = 53.6 bits (123), Expect = 8e-07
Identities = 26/86 (30%), Positives = 44/86 (51%)
Frame = +3
Query: 498 FPQLREVTGYILIYRTKGLRNLGDLFPNLTVVRGMQLFKDFALVIFDNEHLEALGLNSLM 677
F +RE+TG++ I +F NL + G L+ +L+I + + +L SL
Sbjct: 392 FRTVREITGFLNIQSWPPNMTDFSVFSNLVTIGGRVLYSGLSLLILKQQGITSLQFQSLK 451
Query: 678 KIERGGVRIQHNDRLCYTNTIDWSRI 755
+I G + I N LCY +TI+W+ +
Sbjct: 452 EISAGNIYITDNSNLCYYHTINWTTL 477
>BC112199-1|AAI12200.1| 1308|Homo sapiens v-erb-a erythroblastic
leukemia viral oncogene homolog 4 (avian) protein.
Length = 1308
Score = 66.1 bits (154), Expect = 1e-10
Identities = 48/133 (36%), Positives = 68/133 (51%), Gaps = 8/133 (6%)
Frame = +3
Query: 381 DLRNNPDQIRRL-EGCRVIEGQLSIVLMERATNKIFDNMSFPQLREVTGYILIYRTKGLR 557
DL +R+ E C V+ G L I +E + F +REVTGY+L+ + R
Sbjct: 41 DLEQQYRALRKYYENCEVVMGNLEITSIEHNRDLSF----LRSVREVTGYVLVALNQ-FR 95
Query: 558 NLGDLFPNLTVVRGMQLFKD-FALVIFDNEH------LEALGLNSLMKIERGGVRIQHND 716
L NL ++RG +L++D +AL IF N L+ LGL +L +I GGV + N
Sbjct: 96 YLP--LENLRIIRGTKLYEDRYALAIFLNYRKDGNFGLQELGLKNLTEILNGGVYVDQNK 153
Query: 717 RLCYTNTIDWSRI 755
LCY +TI W I
Sbjct: 154 FLCYADTIHWQDI 166
Score = 53.6 bits (123), Expect = 8e-07
Identities = 26/86 (30%), Positives = 44/86 (51%)
Frame = +3
Query: 498 FPQLREVTGYILIYRTKGLRNLGDLFPNLTVVRGMQLFKDFALVIFDNEHLEALGLNSLM 677
F +RE+TG++ I +F NL + G L+ +L+I + + +L SL
Sbjct: 392 FRTVREITGFLNIQSWPPNMTDFSVFSNLVTIGGRVLYSGLSLLILKQQGITSLQFQSLK 451
Query: 678 KIERGGVRIQHNDRLCYTNTIDWSRI 755
+I G + I N LCY +TI+W+ +
Sbjct: 452 EISAGNIYITDNSNLCYYHTINWTTL 477
>X03363-1|CAA27060.1| 1255|Homo sapiens protein ( Human c-erb-B-2
mRNA. ).
Length = 1255
Score = 63.3 bits (147), Expect = 1e-09
Identities = 51/137 (37%), Positives = 74/137 (54%), Gaps = 18/137 (13%)
Frame = +3
Query: 399 DQIRRL-EGCRVIEGQLSIVLMERATNKIFDNMSFPQ-LREVTGYILIYRTKGLRNLGDL 572
D +R L +GC+V++G L + + TN ++SF Q ++EV GY+LI + +R +
Sbjct: 44 DMLRHLYQGCQVVQGNLELTYLP--TNA---SLSFLQDIQEVQGYVLIAHNQ-VRQVP-- 95
Query: 573 FPNLTVVRGMQLFKD-FALVIFDNEH---------------LEALGLNSLMKIERGGVRI 704
L +VRG QLF+D +AL + DN L L L SL +I +GGV I
Sbjct: 96 LQRLRIVRGTQLFEDNYALAVLDNGDPLNNTTPVTGASPGGLRELQLRSLTEILKGGVLI 155
Query: 705 QHNDRLCYTNTIDWSRI 755
Q N +LCY +TI W I
Sbjct: 156 QRNPQLCYQDTILWKDI 172
Score = 50.0 bits (114), Expect = 1e-05
Identities = 29/87 (33%), Positives = 43/87 (49%), Gaps = 1/87 (1%)
Frame = +3
Query: 498 FPQLREVTGYILIYR-TKGLRNLGDLFPNLTVVRGMQLFKDFALVIFDNEHLEALGLNSL 674
F L E+TGY+ I L +L +F NL V+RG L + + LGL SL
Sbjct: 400 FETLEEITGYLYISAWPDSLPDLS-VFQNLQVIRGRILHNGAYSLTLQGLGISWLGLRSL 458
Query: 675 MKIERGGVRIQHNDRLCYTNTIDWSRI 755
++ G I HN LC+ +T+ W ++
Sbjct: 459 RELGSGLALIHHNTHLCFVHTVPWDQL 485
>M16792-1|AAA58637.1| 191|Homo sapiens HER-2/neu protein.
Length = 191
Score = 63.3 bits (147), Expect = 1e-09
Identities = 51/137 (37%), Positives = 74/137 (54%), Gaps = 18/137 (13%)
Frame = +3
Query: 399 DQIRRL-EGCRVIEGQLSIVLMERATNKIFDNMSFPQ-LREVTGYILIYRTKGLRNLGDL 572
D +R L +GC+V++G L + + TN ++SF Q ++EV GY+LI + +R +
Sbjct: 44 DMLRHLYQGCQVVQGNLELTYLP--TNA---SLSFLQDIQEVQGYVLIAHNQ-VRQVP-- 95
Query: 573 FPNLTVVRGMQLFKD-FALVIFDNEH---------------LEALGLNSLMKIERGGVRI 704
L +VRG QLF+D +AL + DN L L L SL +I +GGV I
Sbjct: 96 LQRLRIVRGTQLFEDNYALAVLDNGDPLNNTTPVTGASPGGLRELQLRSLTEILKGGVLI 155
Query: 705 QHNDRLCYTNTIDWSRI 755
Q N +LCY +TI W I
Sbjct: 156 QRNPQLCYQDTILWKDI 172
>M11730-1|AAA75493.1| 1255|Homo sapiens protein ( Human tyrosine
kinase-type receptor (HER2) mRNA, complete cds. ).
Length = 1255
Score = 63.3 bits (147), Expect = 1e-09
Identities = 51/137 (37%), Positives = 74/137 (54%), Gaps = 18/137 (13%)
Frame = +3
Query: 399 DQIRRL-EGCRVIEGQLSIVLMERATNKIFDNMSFPQ-LREVTGYILIYRTKGLRNLGDL 572
D +R L +GC+V++G L + + TN ++SF Q ++EV GY+LI + +R +
Sbjct: 44 DMLRHLYQGCQVVQGNLELTYLP--TNA---SLSFLQDIQEVQGYVLIAHNQ-VRQVP-- 95
Query: 573 FPNLTVVRGMQLFKD-FALVIFDNEH---------------LEALGLNSLMKIERGGVRI 704
L +VRG QLF+D +AL + DN L L L SL +I +GGV I
Sbjct: 96 LQRLRIVRGTQLFEDNYALAVLDNGDPLNNTTPVTGASPGGLRELQLRSLTEILKGGVLI 155
Query: 705 QHNDRLCYTNTIDWSRI 755
Q N +LCY +TI W I
Sbjct: 156 QRNPQLCYQDTILWKDI 172
Score = 50.0 bits (114), Expect = 1e-05
Identities = 29/87 (33%), Positives = 43/87 (49%), Gaps = 1/87 (1%)
Frame = +3
Query: 498 FPQLREVTGYILIYR-TKGLRNLGDLFPNLTVVRGMQLFKDFALVIFDNEHLEALGLNSL 674
F L E+TGY+ I L +L +F NL V+RG L + + LGL SL
Sbjct: 400 FETLEEITGYLYISAWPDSLPDLS-VFQNLQVIRGRILHNGAYSLTLQGLGISWLGLRSL 458
Query: 675 MKIERGGVRIQHNDRLCYTNTIDWSRI 755
++ G I HN LC+ +T+ W ++
Sbjct: 459 RELGSGLALIHHNTHLCFVHTVPWDQL 485
>AY208911-1|AAO18082.1| 1255|Homo sapiens v-erb-b2 erythroblastic
leukemia viral oncogene homolog 2, neuro/glioblastoma d
protein.
Length = 1255
Score = 63.3 bits (147), Expect = 1e-09
Identities = 51/137 (37%), Positives = 74/137 (54%), Gaps = 18/137 (13%)
Frame = +3
Query: 399 DQIRRL-EGCRVIEGQLSIVLMERATNKIFDNMSFPQ-LREVTGYILIYRTKGLRNLGDL 572
D +R L +GC+V++G L + + TN ++SF Q ++EV GY+LI + +R +
Sbjct: 44 DMLRHLYQGCQVVQGNLELTYLP--TNA---SLSFLQDIQEVQGYVLIAHNQ-VRQVP-- 95
Query: 573 FPNLTVVRGMQLFKD-FALVIFDNEH---------------LEALGLNSLMKIERGGVRI 704
L +VRG QLF+D +AL + DN L L L SL +I +GGV I
Sbjct: 96 LQRLRIVRGTQLFEDNYALAVLDNGDPLNNTTPVTGASPGGLRELQLRSLTEILKGGVLI 155
Query: 705 QHNDRLCYTNTIDWSRI 755
Q N +LCY +TI W I
Sbjct: 156 QRNPQLCYQDTILWKDI 172
Score = 50.0 bits (114), Expect = 1e-05
Identities = 29/87 (33%), Positives = 43/87 (49%), Gaps = 1/87 (1%)
Frame = +3
Query: 498 FPQLREVTGYILIYR-TKGLRNLGDLFPNLTVVRGMQLFKDFALVIFDNEHLEALGLNSL 674
F L E+TGY+ I L +L +F NL V+RG L + + LGL SL
Sbjct: 400 FETLEEITGYLYISAWPDSLPDLS-VFQNLQVIRGRILHNGAYSLTLQGLGISWLGLRSL 458
Query: 675 MKIERGGVRIQHNDRLCYTNTIDWSRI 755
++ G I HN LC+ +T+ W ++
Sbjct: 459 RELGSGLALIHHNTHLCFVHTVPWDQL 485
>AF177761-1|AAD56009.2| 419|Homo sapiens herstatin protein.
Length = 419
Score = 63.3 bits (147), Expect = 1e-09
Identities = 51/137 (37%), Positives = 74/137 (54%), Gaps = 18/137 (13%)
Frame = +3
Query: 399 DQIRRL-EGCRVIEGQLSIVLMERATNKIFDNMSFPQ-LREVTGYILIYRTKGLRNLGDL 572
D +R L +GC+V++G L + + TN ++SF Q ++EV GY+LI + +R +
Sbjct: 44 DMLRHLYQGCQVVQGNLELTYLP--TNA---SLSFLQDIQEVQGYVLIAHNQ-VRQVP-- 95
Query: 573 FPNLTVVRGMQLFKD-FALVIFDNEH---------------LEALGLNSLMKIERGGVRI 704
L +VRG QLF+D +AL + DN L L L SL +I +GGV I
Sbjct: 96 LQRLRIVRGTQLFEDNYALAVLDNGDPLNNTTPVTGASPGGLRELQLRSLTEILKGGVLI 155
Query: 705 QHNDRLCYTNTIDWSRI 755
Q N +LCY +TI W I
Sbjct: 156 QRNPQLCYQDTILWKDI 172
>X00663-1|CAA25282.1| 800|Homo sapiens protein ( Human mRNA
fragment for epidermal growth factor (EGF) receptor. ).
Length = 800
Score = 54.8 bits (126), Expect = 4e-07
Identities = 30/84 (35%), Positives = 48/84 (57%), Gaps = 1/84 (1%)
Frame = +3
Query: 507 LREVTGYILIYRTKGLRNLGDLFPNLTVVRGM-QLFKDFALVIFDNEHLEALGLNSLMKI 683
++E+TG++LI R F NL ++RG + F+L + + ++ +LGL SL +I
Sbjct: 256 VKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVV-SLNITSLGLRSLKEI 314
Query: 684 ERGGVRIQHNDRLCYTNTIDWSRI 755
G V I N LCY NTI+W ++
Sbjct: 315 SDGDVIISGNKNLCYANTINWKKL 338
>X00588-1|CAA25240.1| 1210|Homo sapiens epidermal growth factor
receptor protein.
Length = 1210
Score = 54.8 bits (126), Expect = 4e-07
Identities = 30/84 (35%), Positives = 48/84 (57%), Gaps = 1/84 (1%)
Frame = +3
Query: 507 LREVTGYILIYRTKGLRNLGDLFPNLTVVRGM-QLFKDFALVIFDNEHLEALGLNSLMKI 683
++E+TG++LI R F NL ++RG + F+L + + ++ +LGL SL +I
Sbjct: 398 VKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVV-SLNITSLGLRSLKEI 456
Query: 684 ERGGVRIQHNDRLCYTNTIDWSRI 755
G V I N LCY NTI+W ++
Sbjct: 457 SDGDVIISGNKNLCYANTINWKKL 480
Score = 47.6 bits (108), Expect = 5e-05
Identities = 36/124 (29%), Positives = 57/124 (45%), Gaps = 8/124 (6%)
Frame = +3
Query: 408 RRLEGCRVIEGQLSIVLMERATNKIFDNMSFPQLREVTGYILIYRTKGLRNLGDLFP--N 581
R C V+ G L I ++R +D ++EV GY+LI N + P N
Sbjct: 53 RMFNNCEVVLGNLEITYVQRN----YDLSFLKTIQEVAGYVLI-----ALNTVERIPLEN 103
Query: 582 LTVVRGMQLFKD-FALVIFDNEH-----LEALGLNSLMKIERGGVRIQHNDRLCYTNTID 743
L ++RG +++ +AL + N L+ L + +L +I G VR +N LC +I
Sbjct: 104 LQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQ 163
Query: 744 WSRI 755
W I
Sbjct: 164 WRDI 167
>K03193-1|AAA52371.1| 657|Homo sapiens EGFR protein.
Length = 657
Score = 54.8 bits (126), Expect = 4e-07
Identities = 30/84 (35%), Positives = 48/84 (57%), Gaps = 1/84 (1%)
Frame = +3
Query: 507 LREVTGYILIYRTKGLRNLGDLFPNLTVVRGM-QLFKDFALVIFDNEHLEALGLNSLMKI 683
++E+TG++LI R F NL ++RG + F+L + + ++ +LGL SL +I
Sbjct: 398 VKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVV-SLNITSLGLRSLKEI 456
Query: 684 ERGGVRIQHNDRLCYTNTIDWSRI 755
G V I N LCY NTI+W ++
Sbjct: 457 SDGDVIISGNKNLCYANTINWKKL 480
Score = 47.6 bits (108), Expect = 5e-05
Identities = 36/124 (29%), Positives = 57/124 (45%), Gaps = 8/124 (6%)
Frame = +3
Query: 408 RRLEGCRVIEGQLSIVLMERATNKIFDNMSFPQLREVTGYILIYRTKGLRNLGDLFP--N 581
R C V+ G L I ++R +D ++EV GY+LI N + P N
Sbjct: 53 RMFNNCEVVLGNLEITYVQRN----YDLSFLKTIQEVAGYVLI-----ALNTVERIPLEN 103
Query: 582 LTVVRGMQLFKD-FALVIFDNEH-----LEALGLNSLMKIERGGVRIQHNDRLCYTNTID 743
L ++RG +++ +AL + N L+ L + +L +I G VR +N LC +I
Sbjct: 104 LQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQ 163
Query: 744 WSRI 755
W I
Sbjct: 164 WRDI 167
>BC128419-1|AAI28420.1| 388|Homo sapiens EGFR protein protein.
Length = 388
Score = 54.8 bits (126), Expect = 4e-07
Identities = 30/84 (35%), Positives = 48/84 (57%), Gaps = 1/84 (1%)
Frame = +3
Query: 507 LREVTGYILIYRTKGLRNLGDLFPNLTVVRGM-QLFKDFALVIFDNEHLEALGLNSLMKI 683
++E+TG++LI R F NL ++RG + F+L + + ++ +LGL SL +I
Sbjct: 126 VKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVV-SLNITSLGLRSLKEI 184
Query: 684 ERGGVRIQHNDRLCYTNTIDWSRI 755
G V I N LCY NTI+W ++
Sbjct: 185 SDGDVIISGNKNLCYANTINWKKL 208
>BC118665-1|AAI18666.1| 464|Homo sapiens EGFR protein protein.
Length = 464
Score = 54.8 bits (126), Expect = 4e-07
Identities = 30/84 (35%), Positives = 48/84 (57%), Gaps = 1/84 (1%)
Frame = +3
Query: 507 LREVTGYILIYRTKGLRNLGDLFPNLTVVRGM-QLFKDFALVIFDNEHLEALGLNSLMKI 683
++E+TG++LI R F NL ++RG + F+L + + ++ +LGL SL +I
Sbjct: 192 VKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVV-SLNITSLGLRSLKEI 250
Query: 684 ERGGVRIQHNDRLCYTNTIDWSRI 755
G V I N LCY NTI+W ++
Sbjct: 251 SDGDVIISGNKNLCYANTINWKKL 274
>BC094761-1|AAH94761.1| 1091|Homo sapiens EGFR protein protein.
Length = 1091
Score = 54.8 bits (126), Expect = 4e-07
Identities = 30/84 (35%), Positives = 48/84 (57%), Gaps = 1/84 (1%)
Frame = +3
Query: 507 LREVTGYILIYRTKGLRNLGDLFPNLTVVRGM-QLFKDFALVIFDNEHLEALGLNSLMKI 683
++E+TG++LI R F NL ++RG + F+L + + ++ +LGL SL +I
Sbjct: 353 VKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVV-SLNITSLGLRSLKEI 411
Query: 684 ERGGVRIQHNDRLCYTNTIDWSRI 755
G V I N LCY NTI+W ++
Sbjct: 412 SDGDVIISGNKNLCYANTINWKKL 435
>AY698023-1|AAT97978.1| 645|Homo sapiens epidermal growth factor
receptor protein.
Length = 645
Score = 54.8 bits (126), Expect = 4e-07
Identities = 30/84 (35%), Positives = 48/84 (57%), Gaps = 1/84 (1%)
Frame = +3
Query: 507 LREVTGYILIYRTKGLRNLGDLFPNLTVVRGM-QLFKDFALVIFDNEHLEALGLNSLMKI 683
++E+TG++LI R F NL ++RG + F+L + + ++ +LGL SL +I
Sbjct: 398 VKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVV-SLNITSLGLRSLKEI 456
Query: 684 ERGGVRIQHNDRLCYTNTIDWSRI 755
G V I N LCY NTI+W ++
Sbjct: 457 SDGDVIISGNKNLCYANTINWKKL 480
Score = 47.6 bits (108), Expect = 5e-05
Identities = 36/124 (29%), Positives = 57/124 (45%), Gaps = 8/124 (6%)
Frame = +3
Query: 408 RRLEGCRVIEGQLSIVLMERATNKIFDNMSFPQLREVTGYILIYRTKGLRNLGDLFP--N 581
R C V+ G L I ++R +D ++EV GY+LI N + P N
Sbjct: 53 RMFNNCEVVLGNLEITYVQRN----YDLSFLKTIQEVAGYVLI-----ALNTVERIPLEN 103
Query: 582 LTVVRGMQLFKD-FALVIFDNEH-----LEALGLNSLMKIERGGVRIQHNDRLCYTNTID 743
L ++RG +++ +AL + N L+ L + +L +I G VR +N LC +I
Sbjct: 104 LQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQ 163
Query: 744 WSRI 755
W I
Sbjct: 164 WRDI 167
>AY588246-1|AAS83109.1| 1210|Homo sapiens epidermal growth factor
receptor (erythroblastic leukemia viral (v-erb-b) oncog
protein.
Length = 1210
Score = 54.8 bits (126), Expect = 4e-07
Identities = 30/84 (35%), Positives = 48/84 (57%), Gaps = 1/84 (1%)
Frame = +3
Query: 507 LREVTGYILIYRTKGLRNLGDLFPNLTVVRGM-QLFKDFALVIFDNEHLEALGLNSLMKI 683
++E+TG++LI R F NL ++RG + F+L + + ++ +LGL SL +I
Sbjct: 398 VKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVV-SLNITSLGLRSLKEI 456
Query: 684 ERGGVRIQHNDRLCYTNTIDWSRI 755
G V I N LCY NTI+W ++
Sbjct: 457 SDGDVIISGNKNLCYANTINWKKL 480
Score = 47.6 bits (108), Expect = 5e-05
Identities = 36/124 (29%), Positives = 57/124 (45%), Gaps = 8/124 (6%)
Frame = +3
Query: 408 RRLEGCRVIEGQLSIVLMERATNKIFDNMSFPQLREVTGYILIYRTKGLRNLGDLFP--N 581
R C V+ G L I ++R +D ++EV GY+LI N + P N
Sbjct: 53 RMFNNCEVVLGNLEITYVQRN----YDLSFLKTIQEVAGYVLI-----ALNTVERIPLEN 103
Query: 582 LTVVRGMQLFKD-FALVIFDNEH-----LEALGLNSLMKIERGGVRIQHNDRLCYTNTID 743
L ++RG +++ +AL + N L+ L + +L +I G VR +N LC +I
Sbjct: 104 LQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQ 163
Query: 744 WSRI 755
W I
Sbjct: 164 WRDI 167
>AY550966-1|AAT52212.1| 1210|Homo sapiens cell growth inhibiting
protein 40 protein.
Length = 1210
Score = 54.8 bits (126), Expect = 4e-07
Identities = 30/84 (35%), Positives = 48/84 (57%), Gaps = 1/84 (1%)
Frame = +3
Query: 507 LREVTGYILIYRTKGLRNLGDLFPNLTVVRGM-QLFKDFALVIFDNEHLEALGLNSLMKI 683
++E+TG++LI R F NL ++RG + F+L + + ++ +LGL SL +I
Sbjct: 398 VKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVV-SLNITSLGLRSLKEI 456
Query: 684 ERGGVRIQHNDRLCYTNTIDWSRI 755
G V I N LCY NTI+W ++
Sbjct: 457 SDGDVIISGNKNLCYANTINWKKL 480
Score = 47.6 bits (108), Expect = 5e-05
Identities = 36/124 (29%), Positives = 57/124 (45%), Gaps = 8/124 (6%)
Frame = +3
Query: 408 RRLEGCRVIEGQLSIVLMERATNKIFDNMSFPQLREVTGYILIYRTKGLRNLGDLFP--N 581
R C V+ G L I ++R +D ++EV GY+LI N + P N
Sbjct: 53 RMFNNCEVVLGNLEITYVQRN----YDLSFLKTIQEVAGYVLI-----ALNTVERIPLEN 103
Query: 582 LTVVRGMQLFKD-FALVIFDNEH-----LEALGLNSLMKIERGGVRIQHNDRLCYTNTID 743
L ++RG +++ +AL + N L+ L + +L +I G VR +N LC +I
Sbjct: 104 LQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQ 163
Query: 744 WSRI 755
W I
Sbjct: 164 WRDI 167
>AF288738-4|AAG35790.1| 628|Homo sapiens truncated epidermal growth
factor receptor protein.
Length = 628
Score = 54.8 bits (126), Expect = 4e-07
Identities = 30/84 (35%), Positives = 48/84 (57%), Gaps = 1/84 (1%)
Frame = +3
Query: 507 LREVTGYILIYRTKGLRNLGDLFPNLTVVRGM-QLFKDFALVIFDNEHLEALGLNSLMKI 683
++E+TG++LI R F NL ++RG + F+L + + ++ +LGL SL +I
Sbjct: 398 VKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVV-SLNITSLGLRSLKEI 456
Query: 684 ERGGVRIQHNDRLCYTNTIDWSRI 755
G V I N LCY NTI+W ++
Sbjct: 457 SDGDVIISGNKNLCYANTINWKKL 480
Score = 47.6 bits (108), Expect = 5e-05
Identities = 36/124 (29%), Positives = 57/124 (45%), Gaps = 8/124 (6%)
Frame = +3
Query: 408 RRLEGCRVIEGQLSIVLMERATNKIFDNMSFPQLREVTGYILIYRTKGLRNLGDLFP--N 581
R C V+ G L I ++R +D ++EV GY+LI N + P N
Sbjct: 53 RMFNNCEVVLGNLEITYVQRN----YDLSFLKTIQEVAGYVLI-----ALNTVERIPLEN 103
Query: 582 LTVVRGMQLFKD-FALVIFDNEH-----LEALGLNSLMKIERGGVRIQHNDRLCYTNTID 743
L ++RG +++ +AL + N L+ L + +L +I G VR +N LC +I
Sbjct: 104 LQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQ 163
Query: 744 WSRI 755
W I
Sbjct: 164 WRDI 167
>AF288738-3|AAG35786.1| 705|Homo sapiens p110 epidermal growth
factor receptor protein.
Length = 705
Score = 54.8 bits (126), Expect = 4e-07
Identities = 30/84 (35%), Positives = 48/84 (57%), Gaps = 1/84 (1%)
Frame = +3
Query: 507 LREVTGYILIYRTKGLRNLGDLFPNLTVVRGM-QLFKDFALVIFDNEHLEALGLNSLMKI 683
++E+TG++LI R F NL ++RG + F+L + + ++ +LGL SL +I
Sbjct: 398 VKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVV-SLNITSLGLRSLKEI 456
Query: 684 ERGGVRIQHNDRLCYTNTIDWSRI 755
G V I N LCY NTI+W ++
Sbjct: 457 SDGDVIISGNKNLCYANTINWKKL 480
Score = 47.6 bits (108), Expect = 5e-05
Identities = 36/124 (29%), Positives = 57/124 (45%), Gaps = 8/124 (6%)
Frame = +3
Query: 408 RRLEGCRVIEGQLSIVLMERATNKIFDNMSFPQLREVTGYILIYRTKGLRNLGDLFP--N 581
R C V+ G L I ++R +D ++EV GY+LI N + P N
Sbjct: 53 RMFNNCEVVLGNLEITYVQRN----YDLSFLKTIQEVAGYVLI-----ALNTVERIPLEN 103
Query: 582 LTVVRGMQLFKD-FALVIFDNEH-----LEALGLNSLMKIERGGVRIQHNDRLCYTNTID 743
L ++RG +++ +AL + N L+ L + +L +I G VR +N LC +I
Sbjct: 104 LQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQ 163
Query: 744 WSRI 755
W I
Sbjct: 164 WRDI 167
>AF288738-2|AAG35788.1| 657|Homo sapiens A431-specific p115
epidermal growth factor receptor protein.
Length = 657
Score = 54.8 bits (126), Expect = 4e-07
Identities = 30/84 (35%), Positives = 48/84 (57%), Gaps = 1/84 (1%)
Frame = +3
Query: 507 LREVTGYILIYRTKGLRNLGDLFPNLTVVRGM-QLFKDFALVIFDNEHLEALGLNSLMKI 683
++E+TG++LI R F NL ++RG + F+L + + ++ +LGL SL +I
Sbjct: 398 VKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVV-SLNITSLGLRSLKEI 456
Query: 684 ERGGVRIQHNDRLCYTNTIDWSRI 755
G V I N LCY NTI+W ++
Sbjct: 457 SDGDVIISGNKNLCYANTINWKKL 480
Score = 47.6 bits (108), Expect = 5e-05
Identities = 36/124 (29%), Positives = 57/124 (45%), Gaps = 8/124 (6%)
Frame = +3
Query: 408 RRLEGCRVIEGQLSIVLMERATNKIFDNMSFPQLREVTGYILIYRTKGLRNLGDLFP--N 581
R C V+ G L I ++R +D ++EV GY+LI N + P N
Sbjct: 53 RMFNNCEVVLGNLEITYVQRN----YDLSFLKTIQEVAGYVLI-----ALNTVERIPLEN 103
Query: 582 LTVVRGMQLFKD-FALVIFDNEH-----LEALGLNSLMKIERGGVRIQHNDRLCYTNTID 743
L ++RG +++ +AL + N L+ L + +L +I G VR +N LC +I
Sbjct: 104 LQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQ 163
Query: 744 WSRI 755
W I
Sbjct: 164 WRDI 167
>AF288738-1|AAG35789.1| 1210|Homo sapiens p170 epidermal growth
factor receptor protein.
Length = 1210
Score = 54.8 bits (126), Expect = 4e-07
Identities = 30/84 (35%), Positives = 48/84 (57%), Gaps = 1/84 (1%)
Frame = +3
Query: 507 LREVTGYILIYRTKGLRNLGDLFPNLTVVRGM-QLFKDFALVIFDNEHLEALGLNSLMKI 683
++E+TG++LI R F NL ++RG + F+L + + ++ +LGL SL +I
Sbjct: 398 VKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVV-SLNITSLGLRSLKEI 456
Query: 684 ERGGVRIQHNDRLCYTNTIDWSRI 755
G V I N LCY NTI+W ++
Sbjct: 457 SDGDVIISGNKNLCYANTINWKKL 480
Score = 47.6 bits (108), Expect = 5e-05
Identities = 36/124 (29%), Positives = 57/124 (45%), Gaps = 8/124 (6%)
Frame = +3
Query: 408 RRLEGCRVIEGQLSIVLMERATNKIFDNMSFPQLREVTGYILIYRTKGLRNLGDLFP--N 581
R C V+ G L I ++R +D ++EV GY+LI N + P N
Sbjct: 53 RMFNNCEVVLGNLEITYVQRN----YDLSFLKTIQEVAGYVLI-----ALNTVERIPLEN 103
Query: 582 LTVVRGMQLFKD-FALVIFDNEH-----LEALGLNSLMKIERGGVRIQHNDRLCYTNTID 743
L ++RG +++ +AL + N L+ L + +L +I G VR +N LC +I
Sbjct: 104 LQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQ 163
Query: 744 WSRI 755
W I
Sbjct: 164 WRDI 167
>AF125253-1|AAG43240.1| 705|Homo sapiens truncated epidermal growth
factor receptor precursor protein.
Length = 705
Score = 54.8 bits (126), Expect = 4e-07
Identities = 30/84 (35%), Positives = 48/84 (57%), Gaps = 1/84 (1%)
Frame = +3
Query: 507 LREVTGYILIYRTKGLRNLGDLFPNLTVVRGM-QLFKDFALVIFDNEHLEALGLNSLMKI 683
++E+TG++LI R F NL ++RG + F+L + + ++ +LGL SL +I
Sbjct: 398 VKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVV-SLNITSLGLRSLKEI 456
Query: 684 ERGGVRIQHNDRLCYTNTIDWSRI 755
G V I N LCY NTI+W ++
Sbjct: 457 SDGDVIISGNKNLCYANTINWKKL 480
Score = 47.6 bits (108), Expect = 5e-05
Identities = 36/124 (29%), Positives = 57/124 (45%), Gaps = 8/124 (6%)
Frame = +3
Query: 408 RRLEGCRVIEGQLSIVLMERATNKIFDNMSFPQLREVTGYILIYRTKGLRNLGDLFP--N 581
R C V+ G L I ++R +D ++EV GY+LI N + P N
Sbjct: 53 RMFNNCEVVLGNLEITYVQRN----YDLSFLKTIQEVAGYVLI-----ALNTVERIPLEN 103
Query: 582 LTVVRGMQLFKD-FALVIFDNEH-----LEALGLNSLMKIERGGVRIQHNDRLCYTNTID 743
L ++RG +++ +AL + N L+ L + +L +I G VR +N LC +I
Sbjct: 104 LQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQ 163
Query: 744 WSRI 755
W I
Sbjct: 164 WRDI 167
>AB209442-1|BAD92679.1| 1081|Homo sapiens epidermal growth factor
receptor isoform a variant protein.
Length = 1081
Score = 54.8 bits (126), Expect = 4e-07
Identities = 30/84 (35%), Positives = 48/84 (57%), Gaps = 1/84 (1%)
Frame = +3
Query: 507 LREVTGYILIYRTKGLRNLGDLFPNLTVVRGM-QLFKDFALVIFDNEHLEALGLNSLMKI 683
++E+TG++LI R F NL ++RG + F+L + + ++ +LGL SL +I
Sbjct: 269 VKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVV-SLNITSLGLRSLKEI 327
Query: 684 ERGGVRIQHNDRLCYTNTIDWSRI 755
G V I N LCY NTI+W ++
Sbjct: 328 SDGDVIISGNKNLCYANTINWKKL 351
>AC105921-1|AAY24303.1| 552|Homo sapiens unknown protein.
Length = 552
Score = 53.6 bits (123), Expect = 8e-07
Identities = 26/86 (30%), Positives = 44/86 (51%)
Frame = +3
Query: 498 FPQLREVTGYILIYRTKGLRNLGDLFPNLTVVRGMQLFKDFALVIFDNEHLEALGLNSLM 677
F +RE+TG++ I +F NL + G L+ +L+I + + +L SL
Sbjct: 251 FRTVREITGFLNIQSWPPNMTDFSVFSNLVTIGGRVLYSGLSLLILKQQGITSLQFQSLK 310
Query: 678 KIERGGVRIQHNDRLCYTNTIDWSRI 755
+I G + I N LCY +TI+W+ +
Sbjct: 311 EISAGNIYITDNSNLCYYHTINWTTL 336
>U95089-1|AAB53063.1| 405|Homo sapiens truncated epidermal growth
factor receptor-like protein precursor protein.
Length = 405
Score = 47.6 bits (108), Expect = 5e-05
Identities = 36/124 (29%), Positives = 57/124 (45%), Gaps = 8/124 (6%)
Frame = +3
Query: 408 RRLEGCRVIEGQLSIVLMERATNKIFDNMSFPQLREVTGYILIYRTKGLRNLGDLFP--N 581
R C V+ G L I ++R +D ++EV GY+LI N + P N
Sbjct: 53 RMFNNCEVVLGNLEITYVQRN----YDLSFLKTIQEVAGYVLI-----ALNTVERIPLEN 103
Query: 582 LTVVRGMQLFKD-FALVIFDNEH-----LEALGLNSLMKIERGGVRIQHNDRLCYTNTID 743
L ++RG +++ +AL + N L+ L + +L +I G VR +N LC +I
Sbjct: 104 LQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQ 163
Query: 744 WSRI 755
W I
Sbjct: 164 WRDI 167
>U48722-1|AAC50802.1| 405|Homo sapiens epidermal growth factor
receptor precursor protein.
Length = 405
Score = 47.6 bits (108), Expect = 5e-05
Identities = 36/124 (29%), Positives = 57/124 (45%), Gaps = 8/124 (6%)
Frame = +3
Query: 408 RRLEGCRVIEGQLSIVLMERATNKIFDNMSFPQLREVTGYILIYRTKGLRNLGDLFP--N 581
R C V+ G L I ++R +D ++EV GY+LI N + P N
Sbjct: 53 RMFNNCEVVLGNLEITYVQRN----YDLSFLKTIQEVAGYVLI-----ALNTVERIPLEN 103
Query: 582 LTVVRGMQLFKD-FALVIFDNEH-----LEALGLNSLMKIERGGVRIQHNDRLCYTNTID 743
L ++RG +++ +AL + N L+ L + +L +I G VR +N LC +I
Sbjct: 104 LQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQ 163
Query: 744 WSRI 755
W I
Sbjct: 164 WRDI 167
>AY698024-1|AAT97979.1| 405|Homo sapiens epidermal growth factor
receptor short isoform protein.
Length = 405
Score = 47.6 bits (108), Expect = 5e-05
Identities = 36/124 (29%), Positives = 57/124 (45%), Gaps = 8/124 (6%)
Frame = +3
Query: 408 RRLEGCRVIEGQLSIVLMERATNKIFDNMSFPQLREVTGYILIYRTKGLRNLGDLFP--N 581
R C V+ G L I ++R +D ++EV GY+LI N + P N
Sbjct: 53 RMFNNCEVVLGNLEITYVQRN----YDLSFLKTIQEVAGYVLI-----ALNTVERIPLEN 103
Query: 582 LTVVRGMQLFKD-FALVIFDNEH-----LEALGLNSLMKIERGGVRIQHNDRLCYTNTID 743
L ++RG +++ +AL + N L+ L + +L +I G VR +N LC +I
Sbjct: 104 LQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQ 163
Query: 744 WSRI 755
W I
Sbjct: 164 WRDI 167
>AF288738-5|AAG35787.1| 405|Homo sapiens p60 epidermal growth
factor receptor protein.
Length = 405
Score = 47.6 bits (108), Expect = 5e-05
Identities = 36/124 (29%), Positives = 57/124 (45%), Gaps = 8/124 (6%)
Frame = +3
Query: 408 RRLEGCRVIEGQLSIVLMERATNKIFDNMSFPQLREVTGYILIYRTKGLRNLGDLFP--N 581
R C V+ G L I ++R +D ++EV GY+LI N + P N
Sbjct: 53 RMFNNCEVVLGNLEITYVQRN----YDLSFLKTIQEVAGYVLI-----ALNTVERIPLEN 103
Query: 582 LTVVRGMQLFKD-FALVIFDNEH-----LEALGLNSLMKIERGGVRIQHNDRLCYTNTID 743
L ++RG +++ +AL + N L+ L + +L +I G VR +N LC +I
Sbjct: 104 LQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQ 163
Query: 744 WSRI 755
W I
Sbjct: 164 WRDI 167
>AB209697-1|BAD92934.1| 892|Homo sapiens v-erb-a erythroblastic
leukemia viral oncogene homolog 4 variant protein.
Length = 892
Score = 47.2 bits (107), Expect = 7e-05
Identities = 20/62 (32%), Positives = 34/62 (54%)
Frame = +3
Query: 570 LFPNLTVVRGMQLFKDFALVIFDNEHLEALGLNSLMKIERGGVRIQHNDRLCYTNTIDWS 749
+F NL + G L+ +L+I + + +L SL +I G + I N LCY +TI+W+
Sbjct: 16 VFSNLVTIGGRVLYSGLSLLILKQQGITSLQFQSLKEISAGNIYITDNSNLCYYHTINWT 75
Query: 750 RI 755
+
Sbjct: 76 TL 77
>S61953-1|AAB26935.1| 183|Homo sapiens receptor tyrosine kinase
protein.
Length = 183
Score = 43.2 bits (97), Expect = 0.001
Identities = 43/123 (34%), Positives = 60/123 (48%), Gaps = 12/123 (9%)
Frame = +3
Query: 309 LLIACARTYAGTEVVPARGVCPSM--------DLRNNPDQIRRL-EGCRVIEGQLSIVLM 461
LL + AR G+EV ++ VCP D N + +L E C V+ G L IVL
Sbjct: 12 LLFSLAR---GSEVGNSQAVCPGTLNGLSVTGDAENQYQTLYKLYERCEVVMGNLEIVLT 68
Query: 462 ERATNKIFDNMSFPQ-LREVTGYILIYRTKGLRNLGDL-FPNLTVVRGMQLFK-DFALVI 632
+ +SF Q +REVTGY+L+ + L PNL VVRG Q++ FA+ +
Sbjct: 69 GHNAD-----LSFLQWIREVTGYVLV----AMNEFSTLPLPNLRVVRGTQVYDGKFAIFV 119
Query: 633 FDN 641
N
Sbjct: 120 MLN 122
>U48727-1|AAC50799.1| 66|Homo sapiens epidermal growth factor
receptor protein.
Length = 66
Score = 40.7 bits (91), Expect = 0.006
Identities = 17/37 (45%), Positives = 24/37 (64%)
Frame = +3
Query: 645 HLEALGLNSLMKIERGGVRIQHNDRLCYTNTIDWSRI 755
++ +LGL SL +I G V I N LCY NTI+W ++
Sbjct: 11 NITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKL 47
>AC093823-1|AAY14899.1| 62|Homo sapiens unknown protein.
Length = 62
Score = 33.5 bits (73), Expect = 0.93
Identities = 23/58 (39%), Positives = 34/58 (58%), Gaps = 2/58 (3%)
Frame = +3
Query: 507 LREVTGYILIYRTKGLRNLGDLFPNLTVVRGMQLFKD-FALVIFDNEHLEA-LGLNSL 674
+REVTGY+L+ + R L NL ++RG +L++D +AL IF N + GL L
Sbjct: 2 VREVTGYVLVALNQ-FRYLP--LENLRIIRGTKLYEDRYALAIFLNYRKDGNFGLQEL 56
>AL009182-2|CAI22773.1| 639|Homo sapiens chromosome 1 open reading
frame 32 protein.
Length = 639
Score = 31.1 bits (67), Expect = 5.0
Identities = 11/24 (45%), Positives = 12/24 (50%)
Frame = +3
Query: 36 WFVCCPLSIACLQLCCYCFNSLCC 107
W CCP S C C C +S CC
Sbjct: 208 WCQCCPHSCCCYVRCPCCPDSCCC 231
>AF503509-1|AAQ07593.1| 639|Homo sapiens C1orf32 putative protein
protein.
Length = 639
Score = 31.1 bits (67), Expect = 5.0
Identities = 11/24 (45%), Positives = 12/24 (50%)
Frame = +3
Query: 36 WFVCCPLSIACLQLCCYCFNSLCC 107
W CCP S C C C +S CC
Sbjct: 208 WCQCCPHSCCCYVRCPCCPDSCCC 231
>D88667-1|BAA13673.1| 423|Homo sapiens cerebroside sulfotransferase
protein.
Length = 423
Score = 30.7 bits (66), Expect = 6.6
Identities = 18/47 (38%), Positives = 26/47 (55%), Gaps = 2/47 (4%)
Frame = -2
Query: 367 TPRAGTTSVPAYVRAQAISRAHATAG--QPRRSQARLITPRRTSSML 233
TP A + P + +A+ RA+ +AG QPRR+ L T + SS L
Sbjct: 45 TPEAAASCSPPALEPEAVIRANGSAGECQPRRNIVFLKTHKTASSTL 91
>CR456350-1|CAG30236.1| 423|Homo sapiens Em:AC005006.2 protein.
Length = 423
Score = 30.7 bits (66), Expect = 6.6
Identities = 18/47 (38%), Positives = 26/47 (55%), Gaps = 2/47 (4%)
Frame = -2
Query: 367 TPRAGTTSVPAYVRAQAISRAHATAG--QPRRSQARLITPRRTSSML 233
TP A + P + +A+ RA+ +AG QPRR+ L T + SS L
Sbjct: 45 TPEAAASCSPPALEPEAVIRANGSAGECQPRRNIVFLKTHKTASSTL 91
>BC019077-1|AAH19077.1| 423|Homo sapiens
galactose-3-O-sulfotransferase 1 protein.
Length = 423
Score = 30.7 bits (66), Expect = 6.6
Identities = 18/47 (38%), Positives = 26/47 (55%), Gaps = 2/47 (4%)
Frame = -2
Query: 367 TPRAGTTSVPAYVRAQAISRAHATAG--QPRRSQARLITPRRTSSML 233
TP A + P + +A+ RA+ +AG QPRR+ L T + SS L
Sbjct: 45 TPEAAASCSPPALEPEAVIRANGSAGECQPRRNIVFLKTHKTASSTL 91
>BC014649-1|AAH14649.1| 423|Homo sapiens GAL3ST1 protein protein.
Length = 423
Score = 30.7 bits (66), Expect = 6.6
Identities = 18/47 (38%), Positives = 26/47 (55%), Gaps = 2/47 (4%)
Frame = -2
Query: 367 TPRAGTTSVPAYVRAQAISRAHATAG--QPRRSQARLITPRRTSSML 233
TP A + P + +A+ RA+ +AG QPRR+ L T + SS L
Sbjct: 45 TPEAAASCSPPALEPEAVIRANGSAGECQPRRNIVFLKTHKTASSTL 91
>AB029901-1|BAA89503.1| 423|Homo sapiens cerebroside
sulfotransferase protein.
Length = 423
Score = 30.7 bits (66), Expect = 6.6
Identities = 18/47 (38%), Positives = 26/47 (55%), Gaps = 2/47 (4%)
Frame = -2
Query: 367 TPRAGTTSVPAYVRAQAISRAHATAG--QPRRSQARLITPRRTSSML 233
TP A + P + +A+ RA+ +AG QPRR+ L T + SS L
Sbjct: 45 TPEAAASCSPPALEPEAVIRANGSAGECQPRRNIVFLKTHKTASSTL 91
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 114,593,140
Number of Sequences: 237096
Number of extensions: 2456720
Number of successful extensions: 5697
Number of sequences better than 10.0: 58
Number of HSP's better than 10.0 without gapping: 5338
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5648
length of database: 76,859,062
effective HSP length: 89
effective length of database: 55,757,518
effective search space used: 10147868276
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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