Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BmNP03_FL5_P11
(927 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
AJ306454-1|CAC34819.1| 497|Homo sapiens neuronal nicotinic acet... 81 7e-15
Y08416-1|CAA69693.1| 498|Homo sapiens nicotinic acetylcholine r... 79 3e-14
U62439-1|AAB40117.1| 498|Homo sapiens nicotinic acetylcholine r... 79 3e-14
U48861-1|AAA92123.1| 498|Homo sapiens beta 4 nicotinic acetylch... 79 3e-14
BC096082-1|AAH96082.1| 498|Homo sapiens cholinergic receptor, n... 79 3e-14
BC096080-1|AAH96080.1| 498|Homo sapiens cholinergic receptor, n... 79 3e-14
AF306329-1|AAL02062.1| 498|Homo sapiens neuronal nicotinic acet... 79 3e-14
X68275-1|CAA48336.1| 451|Homo sapiens nicotinic receptor beta 4... 75 5e-13
Y08419-1|CAA69696.1| 468|Homo sapiens nicotinic acetylcholine r... 71 8e-12
U62434-1|AAB40112.1| 468|Homo sapiens nicotinic acetylcholine r... 71 8e-12
BC033639-1|AAH33639.1| 468|Homo sapiens cholinergic receptor, n... 71 8e-12
AJ306481-1|CAC34820.1| 468|Homo sapiens neuronal nicotinic acet... 71 8e-12
M86383-1|AAC84176.1| 502|Homo sapiens nicotinic acetylcholine r... 69 2e-11
M83712-1|AAA58357.1| 468|Homo sapiens nicotinic receptor alpha ... 69 2e-11
Y08417-1|CAA69694.1| 458|Homo sapiens nicotinic acetylcholine r... 69 2e-11
X67513-1|CAA47851.1| 423|Homo sapiens nicotinic acetylcholine ... 69 2e-11
U62438-1|AAB40116.1| 458|Homo sapiens nicotinic acetylcholine r... 69 2e-11
BC069788-1|AAH69788.1| 458|Homo sapiens cholinergic receptor, n... 69 2e-11
BC069703-1|AAH69703.1| 458|Homo sapiens cholinergic receptor, n... 69 2e-11
BC069681-1|AAH69681.1| 458|Homo sapiens cholinergic receptor, n... 69 2e-11
AF140765-1|AAD33063.1| 458|Homo sapiens neuronal acetylcholine ... 69 2e-11
Y08415-1|CAA69692.1| 502|Homo sapiens nicotinic acetylcholine r... 68 4e-11
X53179-1|CAA37320.1| 502|Homo sapiens precursor peptide (AA -25... 68 4e-11
U62437-1|AAB40115.1| 502|Homo sapiens nicotinic acetylcholine r... 68 4e-11
BC075041-1|AAH75041.1| 502|Homo sapiens cholinergic receptor, n... 68 4e-11
BC075040-1|AAH75040.1| 502|Homo sapiens cholinergic receptor, n... 68 4e-11
AL592078-3|CAI16184.1| 502|Homo sapiens cholinergic receptor, n... 68 4e-11
AJ001935-1|CAA05108.1| 504|Homo sapiens CHRNB2 protein. 68 4e-11
AF077186-1|AAD45422.1| 502|Homo sapiens neuronal nicotinic acet... 68 4e-11
Y08418-1|CAA69695.1| 503|Homo sapiens nicotinic acetylcholine r... 67 7e-11
X53559-1|CAA37625.1| 474|Homo sapiens neuronal nicotinic acetyl... 67 7e-11
U62432-1|AAB40110.1| 504|Homo sapiens nicotinic acetylcholine r... 67 7e-11
M37981-1|AAA59942.1| 503|Homo sapiens neuronal nicotinic acetyl... 67 7e-11
BT006897-1|AAP35543.1| 505|Homo sapiens cholinergic receptor, n... 67 7e-11
BT006646-1|AAP35292.1| 489|Homo sapiens cholinergic receptor, n... 67 7e-11
BC098443-1|AAH98443.1| 504|Homo sapiens cholinergic receptor, n... 67 7e-11
BC006114-1|AAH06114.1| 489|Homo sapiens CHRNA3 protein protein. 67 7e-11
BC002996-1|AAH02996.1| 505|Homo sapiens cholinergic receptor, n... 67 7e-11
BC001642-1|AAH01642.1| 505|Homo sapiens cholinergic receptor, n... 67 7e-11
BC000513-1|AAH00513.1| 505|Homo sapiens cholinergic receptor, n... 67 7e-11
AJ007783-1|CAA07682.1| 504|Homo sapiens nicotinic acetylcholine... 67 7e-11
AF385584-1|AAK68110.1| 489|Homo sapiens nicotinic cholinergic r... 67 7e-11
Y16281-1|CAA76154.1| 529|Homo sapiens nicotinic acetylcholine r... 66 2e-10
U62431-1|AAB40109.1| 529|Homo sapiens nicotinic acetylcholine r... 66 2e-10
Y08421-1|CAA69698.1| 627|Homo sapiens nicotinic acetylcholine r... 63 1e-09
X89741-1|CAA61893.1| 627|Homo sapiens neuronal acetylcholine re... 63 1e-09
X87629-1|CAA60959.1| 602|Homo sapiens nicotinic acetylcholine r... 63 1e-09
U62433-1|AAB40111.1| 627|Homo sapiens nicotinic acetylcholine r... 63 1e-09
L35901-1|AAA64743.1| 627|Homo sapiens nicotinic acetylcholine r... 63 1e-09
DQ093071-1|AAY88737.1| 627|Homo sapiens cholinergic receptor, n... 63 1e-09
BC096290-1|AAH96290.1| 627|Homo sapiens cholinergic receptor, n... 63 1e-09
Y16282-1|CAA76155.1| 494|Homo sapiens nicotinic acetylcholine r... 63 2e-09
U62435-1|AAB40113.1| 494|Homo sapiens nicotinic acetylcholine r... 63 2e-09
BC014456-1|AAH14456.1| 494|Homo sapiens cholinergic receptor, n... 63 2e-09
AB079251-1|BAC06855.1| 494|Homo sapiens Nicotinic acetylcholine... 63 2e-09
X14830-1|CAA32939.1| 501|Homo sapiens protein ( Human mRNA for ... 62 4e-09
BC011371-1|AAH11371.1| 501|Homo sapiens cholinergic receptor, n... 62 4e-09
BC131799-1|AAI31800.1| 447|Homo sapiens 5-hydroxytryptamine (se... 61 5e-09
DQ644022-1|ABG35128.1| 456|Homo sapiens 5-HT3 receptor subunit ... 61 6e-09
BC101185-1|AAI01186.1| 374|Homo sapiens HTR3E protein protein. 61 6e-09
BC101183-1|AAI01184.1| 471|Homo sapiens 5-hydroxytryptamine (se... 61 6e-09
BC101182-1|AAI01183.1| 471|Homo sapiens 5-hydroxytryptamine (se... 61 6e-09
AY159813-1|AAO38167.2| 471|Homo sapiens 5-hydroxytryptamine ser... 61 6e-09
AF459285-1|AAL66182.1| 447|Homo sapiens 5-hydroxytryptamine rec... 61 6e-09
BC023553-1|AAH23553.1| 501|Homo sapiens cholinergic receptor, n... 60 8e-09
X01715-1|CAA25861.1| 520|Homo sapiens acetylcholine receptor ga... 60 1e-08
AC092165-3|AAY24103.1| 520|Homo sapiens unknown protein. 60 1e-08
X66403-1|CAA47030.1| 493|Homo sapiens acetylcholine receptor ep... 60 1e-08
AF105999-1|AAD24503.1| 493|Homo sapiens acetylcholine receptor ... 60 1e-08
AY349353-1|AAQ93477.1| 456|Homo sapiens 5-HT3c1 serotonin recep... 59 2e-08
AY349352-1|AAQ93476.1| 441|Homo sapiens 5-HT3c1 serotonin recep... 59 2e-08
Y00762-1|CAA68731.1| 457|Homo sapiens protein ( Human mRNA for ... 56 1e-07
X02502-1|CAA26344.1| 457|Homo sapiens acetylcholine receptor pr... 56 1e-07
S77094-1|AAD14247.1| 457|Homo sapiens nicotinic acetylcholine r... 56 1e-07
BC110597-1|AAI10598.1| 411|Homo sapiens ligand-gated ion channe... 56 1e-07
BC006314-1|AAH06314.1| 269|Homo sapiens CHRNA1 protein protein. 56 1e-07
AF512521-1|AAO20969.1| 411|Homo sapiens ligand-gated ion channe... 56 1e-07
AC018890-1|AAY14687.1| 457|Homo sapiens unknown protein. 56 1e-07
AJ295237-1|CAC16144.1| 450|Homo sapiens neuronal nicotinic acet... 56 2e-07
AJ278118-1|CAC20435.1| 450|Homo sapiens neuronal nicotinic acet... 56 2e-07
AF327367-1|AAK14333.1| 450|Homo sapiens nicotinic acetylcholine... 56 2e-07
AF199235-1|AAG00795.2| 450|Homo sapiens nicotinic acetylcholine... 56 2e-07
AB223030-1|BAE19924.1| 411|Homo sapiens ligand-gated ion-channe... 56 2e-07
X55019-1|CAA38759.1| 517|Homo sapiens acetylcholine receptor de... 56 2e-07
BC093925-1|AAH93925.1| 517|Homo sapiens cholinergic receptor, n... 56 2e-07
BC093923-1|AAH93923.1| 517|Homo sapiens cholinergic receptor, n... 56 2e-07
AC092165-2|AAY24102.1| 517|Homo sapiens unknown protein. 56 2e-07
M59216-1|AAA35862.1| 474|Homo sapiens gamma-aminobutyric acid r... 55 4e-07
L08485-1|AAA58490.1| 462|Homo sapiens GABA-benzodiazepine recep... 55 4e-07
BT009830-1|AAP88832.1| 462|Homo sapiens gamma-aminobutyric acid... 55 4e-07
BC113422-1|AAI13423.1| 462|Homo sapiens gamma-aminobutyric acid... 55 4e-07
BC111979-1|AAI11980.1| 462|Homo sapiens gamma-aminobutyric acid... 55 4e-07
S77554-1|AAB33983.1| 474|Homo sapiens GABAA receptor beta 2 sub... 54 6e-07
S77553-1|AAB33982.1| 512|Homo sapiens GABAA receptor beta 2 sub... 54 6e-07
S67368-1|AAB29370.1| 474|Homo sapiens gamma-aminobutyric acid A... 54 6e-07
BC105639-1|AAI05640.1| 474|Homo sapiens GABRB2 protein protein. 54 6e-07
BC099719-1|AAH99719.1| 474|Homo sapiens GABRB2 protein protein. 54 6e-07
BC099705-1|AAH99705.1| 474|Homo sapiens GABRB2 protein protein. 54 6e-07
X14767-1|CAA32875.1| 474|Homo sapiens GABA-A receptor beta 1 su... 54 7e-07
BC028629-1|AAH28629.1| 492|Homo sapiens gamma-aminobutyric acid... 54 7e-07
Z23141-1|CAA80672.1| 479|Homo sapiens cholinergic receptor, nic... 54 1e-06
Y08420-1|CAA69697.1| 502|Homo sapiens nicotinic acetylcholine r... 54 1e-06
X70297-1|CAA49778.1| 502|Homo sapiens neuronal nicotinic acetyl... 54 1e-06
U62436-1|AAB40114.1| 502|Homo sapiens nicotinic acetylcholine r... 54 1e-06
S62908-1|AAB27279.1| 492|Homo sapiens gamma-aminobutyric acidA ... 54 1e-06
AJ586911-1|CAE52911.1| 502|Homo sapiens nicotinic acetylcholine... 54 1e-06
AF166361-1|AAG12455.1| 492|Homo sapiens GABA receptor subunit a... 54 1e-06
U77731-2|AAB38273.1| 360|Homo sapiens glycine receptor alpha 2B... 53 2e-06
M82919-1|AAA52511.1| 473|Homo sapiens GABA-alpha receptor beta-... 53 2e-06
CR450343-1|CAG29339.1| 452|Homo sapiens GLRA2 protein. 53 2e-06
AY437084-1|AAR87843.1| 452|Homo sapiens glycine receptor alpha2... 53 2e-06
X52008-1|CAA36257.1| 452|Homo sapiens inhibitory glycine recept... 52 2e-06
U77731-1|AAB38272.1| 360|Homo sapiens glycine receptor alpha 2 ... 52 2e-06
BC113575-1|AAI13576.1| 479|Homo sapiens cholinergic receptor, n... 52 2e-06
BC113549-1|AAI13550.1| 479|Homo sapiens cholinergic receptor, n... 52 2e-06
BC032864-1|AAH32864.1| 452|Homo sapiens glycine receptor, alpha... 52 2e-06
AY437083-1|AAR87842.1| 452|Homo sapiens glycine receptor alpha2... 52 2e-06
AY123244-1|AAM74523.1| 479|Homo sapiens nicotinic acetylcholine... 52 2e-06
AJ243342-1|CAB65091.1| 479|Homo sapiens nicotinic acetylcholine... 52 2e-06
AF227732-1|AAF61920.1| 470|Homo sapiens nicotinic acetylcholine... 52 2e-06
AF053495-1|AAC35290.1| 452|Homo sapiens glycine receptor alpha ... 52 2e-06
AC118275-1|AAY40986.1| 479|Homo sapiens unknown protein. 52 2e-06
U40583-1|AAA83561.1| 502|Homo sapiens alpha 7 neuronal nicotini... 52 3e-06
AF385585-1|AAK68111.1| 502|Homo sapiens nicotinic cholinergic r... 52 3e-06
U33267-1|AAB37750.1| 497|Homo sapiens glycine receptor beta sub... 52 4e-06
BC032635-1|AAH32635.1| 497|Homo sapiens glycine receptor, beta ... 52 4e-06
AF094755-1|AAC71034.1| 497|Homo sapiens glycine receptor beta s... 52 4e-06
AF094754-1|AAC71033.1| 497|Homo sapiens glycine receptor beta s... 52 4e-06
S82769-1|AAB39369.1| 467|Homo sapiens GABAA receptor gamma 3 su... 51 5e-06
AK122638-1|BAC85499.1| 266|Homo sapiens yte protein of 76kDa) (... 51 5e-06
AF269144-1|AAF99698.1| 467|Homo sapiens GABAA receptor gamma 3 ... 51 5e-06
AF228458-1|AAF63215.1| 449|Homo sapiens GABAA receptor gamma 3 ... 51 5e-06
S81944-1|AAB36480.1| 453|Homo sapiens gamma-aminobutyric acid t... 50 9e-06
BC099641-1|AAH99641.1| 453|Homo sapiens gamma-aminobutyric acid... 50 9e-06
BC099640-1|AAH99640.1| 453|Homo sapiens gamma-aminobutyric acid... 50 9e-06
BC096242-1|AAH96242.1| 453|Homo sapiens gamma-aminobutyric acid... 50 9e-06
BC096241-1|AAH96241.1| 453|Homo sapiens gamma-aminobutyric acid... 50 9e-06
BC010641-1|AAH10641.1| 473|Homo sapiens gamma-aminobutyric acid... 50 1e-05
AJ003080-1|CAA05853.1| 238|Homo sapiens serotonin receptor prot... 50 1e-05
U30461-1|AAB52519.1| 554|Homo sapiens GABAA receptor subunit al... 50 2e-05
S82612-1|AAB37533.2| 478|Homo sapiens 5-hydroxytryptamine type ... 50 2e-05
BC035055-1|AAH35055.1| 554|Homo sapiens gamma-aminobutyric acid... 50 2e-05
BC022449-1|AAH22449.1| 474|Homo sapiens gamma-aminobutyric acid... 50 2e-05
D49394-1|BAA08387.1| 478|Homo sapiens serotonin 5-HT3 receptor ... 49 2e-05
BT007204-1|AAP35868.1| 484|Homo sapiens 5-hydroxytryptamine (se... 49 2e-05
BC004453-1|AAH04453.2| 478|Homo sapiens 5-hydroxytryptamine (se... 49 2e-05
BC002354-1|AAH02354.1| 478|Homo sapiens 5-hydroxytryptamine (se... 49 2e-05
AJ005205-1|CAA06442.3| 478|Homo sapiens serotonin 3 receptor pr... 49 2e-05
AJ003079-1|CAA05852.1| 478|Homo sapiens 5-hydroxytryptamine3 re... 49 2e-05
AJ003078-1|CAA05851.1| 510|Homo sapiens serotonin receptor prot... 49 2e-05
AF498984-1|AAM21131.1| 478|Homo sapiens 5-hydroxytryptamine rec... 49 2e-05
BC111802-1|AAI11803.1| 465|Homo sapiens CHRNG protein protein. 49 3e-05
X52009-1|CAA36258.1| 449|Homo sapiens inhibitory glycine recept... 48 4e-05
BC114947-1|AAI14948.1| 457|Homo sapiens GLRA1 protein protein. 48 4e-05
BC109211-1|AAI09212.1| 632|Homo sapiens gamma-aminobutyric acid... 48 4e-05
BC109210-1|AAI09211.1| 632|Homo sapiens gamma-aminobutyric acid... 48 4e-05
BC074980-1|AAH74980.1| 449|Homo sapiens glycine receptor, alpha... 48 4e-05
AF189259-1|AAF70380.1| 632|Homo sapiens GABA-A receptor theta s... 48 4e-05
AF144648-1|AAD51172.1| 627|Homo sapiens GABA-A receptor theta p... 48 4e-05
BC033801-1|AAH33801.1| 452|Homo sapiens gamma-aminobutyric acid... 48 5e-05
AL391845-4|CAI15436.1| 452|Homo sapiens gamma-aminobutyric acid... 48 5e-05
AF016917-1|AAB70007.1| 452|Homo sapiens GABA-A receptor delta s... 48 5e-05
Z93848-1|CAI41994.1| 376|Homo sapiens glycine receptor, alpha 4... 46 1e-04
U93917-1|AAC39917.1| 449|Homo sapiens glycine receptor alpha 3 ... 46 1e-04
BC036086-1|AAH36086.1| 464|Homo sapiens glycine receptor, alpha... 46 1e-04
AL049610-1|CAI42158.1| 376|Homo sapiens glycine receptor, alpha... 46 1e-04
AF017724-1|AAC39919.1| 465|Homo sapiens glycine receptor alpha ... 46 1e-04
BC114967-1|AAI14968.1| 366|Homo sapiens GLRA1 protein protein. 46 2e-04
U95367-1|AAC51357.1| 440|Homo sapiens GABA-A receptor pi subuni... 46 3e-04
BC109106-1|AAI09107.1| 440|Homo sapiens gamma-aminobutyric acid... 46 3e-04
BC109105-1|AAI09106.1| 440|Homo sapiens gamma-aminobutyric acid... 46 3e-04
BC096083-1|AAH96083.1| 198|Homo sapiens CHRNB4 protein protein. 46 3e-04
BC096081-1|AAH96081.1| 198|Homo sapiens CHRNB4 protein protein. 46 3e-04
BC074865-1|AAH74865.1| 440|Homo sapiens gamma-aminobutyric acid... 46 3e-04
BC074810-1|AAH74810.1| 440|Homo sapiens gamma-aminobutyric acid... 46 3e-04
AF009702-1|AAC24194.1| 440|Homo sapiens GABA-A receptor pi subu... 46 3e-04
BC031087-1|AAH31087.1| 465|Homo sapiens gamma-aminobutyric acid... 45 5e-04
BC074795-1|AAH74795.1| 467|Homo sapiens gamma-aminobutyric acid... 44 6e-04
BC069348-1|AAH69348.1| 467|Homo sapiens gamma-aminobutyric acid... 44 6e-04
BC059389-1|AAH59389.1| 475|Homo sapiens gamma-aminobutyric acid... 44 6e-04
AF165124-1|AAD50273.1| 467|Homo sapiens gamma-aminobutyric acid... 44 6e-04
X15376-1|CAA33437.1| 467|Homo sapiens GABA-A receptor gamma 2 s... 43 0.001
AM293589-1|CAL25321.1| 430|Homo sapiens 5-hydroxytryptamine rec... 43 0.002
AF169255-1|AAF03691.1| 441|Homo sapiens 5-hydroxytryptamine 3 r... 42 0.004
AF080582-1|AAD12242.1| 441|Homo sapiens 5-hydroxytryptamine 3 r... 42 0.004
AB209359-1|BAD92596.1| 533|Homo sapiens cholinergic receptor, n... 41 0.007
BC096291-1|AAH96291.1| 556|Homo sapiens CHRNA4 protein protein. 40 0.013
>AJ306454-1|CAC34819.1| 497|Homo sapiens neuronal nicotinic
acetylcholine receptor beta-4 subunit protein.
Length = 497
Score = 80.6 bits (190), Expect = 7e-15
Identities = 55/192 (28%), Positives = 89/192 (46%), Gaps = 11/192 (5%)
Frame = +3
Query: 93 AIASAAECENATSLSLMIDSLL--ATYD---RDSPPDSKIV-VNLTLHLRHA-NIRESES 251
A+ C A + ++D LL Y+ R + S+++ + L L L ++ E E
Sbjct: 14 ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQ 73
Query: 252 TVRIQADLQMNWIDKRLSWNAGGV-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRAR 428
+ L+ W D RL+WN+ G + + ++R+W PD+VL N T
Sbjct: 74 IMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNDGTYEVSVYTNLI 133
Query: 429 VSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHTSDEMDFVIDKRIYSMFE 608
V +NGSV W+ + +++ +P D Q CT KF S + E+D V+ SM +
Sbjct: 134 VRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRSWTYDHTEIDMVLMTPTASMDD 193
Query: 609 ---SGPWDVTAL 635
SG WD+ AL
Sbjct: 194 FTPSGEWDIVAL 205
>Y08416-1|CAA69693.1| 498|Homo sapiens nicotinic acetylcholine
receptor beta4 subunit precursor protein.
Length = 498
Score = 78.6 bits (185), Expect = 3e-14
Identities = 56/193 (29%), Positives = 90/193 (46%), Gaps = 12/193 (6%)
Frame = +3
Query: 93 AIASAAECENATSLSLMIDSLL--ATYD---RDSPPDSKIV-VNLTLHLRHA-NIRESES 251
A+ C A + ++D LL Y+ R + S+++ + L L L ++ E E
Sbjct: 14 ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQ 73
Query: 252 TVRIQADLQMNWIDKRLSWNAGGV-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRA 425
+ L+ W D RL+WN+ G + + ++R+W PD+VL N A T
Sbjct: 74 IMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNADGTYEVSVYTNL 133
Query: 426 RVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHTSDEMDFVIDKRIYSMF 605
V +NGSV W+ + +++ +P D Q CT KF S + E+D V+ SM
Sbjct: 134 IVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRSWTYDHTEIDMVLMTPTASMD 193
Query: 606 E---SGPWDVTAL 635
+ SG WD+ AL
Sbjct: 194 DFTPSGEWDIVAL 206
>U62439-1|AAB40117.1| 498|Homo sapiens nicotinic acetylcholine
receptor beta4 subunit precursor protein.
Length = 498
Score = 78.6 bits (185), Expect = 3e-14
Identities = 56/193 (29%), Positives = 90/193 (46%), Gaps = 12/193 (6%)
Frame = +3
Query: 93 AIASAAECENATSLSLMIDSLL--ATYD---RDSPPDSKIV-VNLTLHLRHA-NIRESES 251
A+ C A + ++D LL Y+ R + S+++ + L L L ++ E E
Sbjct: 14 ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQ 73
Query: 252 TVRIQADLQMNWIDKRLSWNAGGV-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRA 425
+ L+ W D RL+WN+ G + + ++R+W PD+VL N A T
Sbjct: 74 IMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNADGTYEVSVYTNL 133
Query: 426 RVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHTSDEMDFVIDKRIYSMF 605
V +NGSV W+ + +++ +P D Q CT KF S + E+D V+ SM
Sbjct: 134 IVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRSWTYDHTEIDMVLMTPTASMD 193
Query: 606 E---SGPWDVTAL 635
+ SG WD+ AL
Sbjct: 194 DFTPSGEWDIVAL 206
>U48861-1|AAA92123.1| 498|Homo sapiens beta 4 nicotinic
acetylcholine receptor subunit protein.
Length = 498
Score = 78.6 bits (185), Expect = 3e-14
Identities = 56/193 (29%), Positives = 90/193 (46%), Gaps = 12/193 (6%)
Frame = +3
Query: 93 AIASAAECENATSLSLMIDSLL--ATYD---RDSPPDSKIV-VNLTLHLRHA-NIRESES 251
A+ C A + ++D LL Y+ R + S+++ + L L L ++ E E
Sbjct: 14 ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQ 73
Query: 252 TVRIQADLQMNWIDKRLSWNAGGV-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRA 425
+ L+ W D RL+WN+ G + + ++R+W PD+VL N A T
Sbjct: 74 IMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNADGTYEVSVYTNL 133
Query: 426 RVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHTSDEMDFVIDKRIYSMF 605
V +NGSV W+ + +++ +P D Q CT KF S + E+D V+ SM
Sbjct: 134 IVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRSWTYDHTEIDMVLMTPTASMD 193
Query: 606 E---SGPWDVTAL 635
+ SG WD+ AL
Sbjct: 194 DFTPSGEWDIVAL 206
>BC096082-1|AAH96082.1| 498|Homo sapiens cholinergic receptor,
nicotinic, beta 4 protein.
Length = 498
Score = 78.6 bits (185), Expect = 3e-14
Identities = 56/193 (29%), Positives = 90/193 (46%), Gaps = 12/193 (6%)
Frame = +3
Query: 93 AIASAAECENATSLSLMIDSLL--ATYD---RDSPPDSKIV-VNLTLHLRHA-NIRESES 251
A+ C A + ++D LL Y+ R + S+++ + L L L ++ E E
Sbjct: 14 ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQ 73
Query: 252 TVRIQADLQMNWIDKRLSWNAGGV-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRA 425
+ L+ W D RL+WN+ G + + ++R+W PD+VL N A T
Sbjct: 74 IMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNADGTYEVSVYTNL 133
Query: 426 RVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHTSDEMDFVIDKRIYSMF 605
V +NGSV W+ + +++ +P D Q CT KF S + E+D V+ SM
Sbjct: 134 IVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRSWTYDHTEIDMVLMTPTASMD 193
Query: 606 E---SGPWDVTAL 635
+ SG WD+ AL
Sbjct: 194 DFTPSGEWDIVAL 206
>BC096080-1|AAH96080.1| 498|Homo sapiens cholinergic receptor,
nicotinic, beta 4 protein.
Length = 498
Score = 78.6 bits (185), Expect = 3e-14
Identities = 56/193 (29%), Positives = 90/193 (46%), Gaps = 12/193 (6%)
Frame = +3
Query: 93 AIASAAECENATSLSLMIDSLL--ATYD---RDSPPDSKIV-VNLTLHLRHA-NIRESES 251
A+ C A + ++D LL Y+ R + S+++ + L L L ++ E E
Sbjct: 14 ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQ 73
Query: 252 TVRIQADLQMNWIDKRLSWNAGGV-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRA 425
+ L+ W D RL+WN+ G + + ++R+W PD+VL N A T
Sbjct: 74 IMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNADGTYEVSVYTNL 133
Query: 426 RVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHTSDEMDFVIDKRIYSMF 605
V +NGSV W+ + +++ +P D Q CT KF S + E+D V+ SM
Sbjct: 134 IVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRSWTYDHTEIDMVLMTPTASMD 193
Query: 606 E---SGPWDVTAL 635
+ SG WD+ AL
Sbjct: 194 DFTPSGEWDIVAL 206
>AF306329-1|AAL02062.1| 498|Homo sapiens neuronal nicotinic
acetylcholine receptor beta 4 subunit protein.
Length = 498
Score = 78.6 bits (185), Expect = 3e-14
Identities = 56/193 (29%), Positives = 90/193 (46%), Gaps = 12/193 (6%)
Frame = +3
Query: 93 AIASAAECENATSLSLMIDSLL--ATYD---RDSPPDSKIV-VNLTLHLRHA-NIRESES 251
A+ C A + ++D LL Y+ R + S+++ + L L L ++ E E
Sbjct: 14 ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQ 73
Query: 252 TVRIQADLQMNWIDKRLSWNAGGV-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRA 425
+ L+ W D RL+WN+ G + + ++R+W PD+VL N A T
Sbjct: 74 IMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNADGTYEVSVYTNL 133
Query: 426 RVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHTSDEMDFVIDKRIYSMF 605
V +NGSV W+ + +++ +P D Q CT KF S + E+D V+ SM
Sbjct: 134 IVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRSWTYDHTEIDMVLMTPTASMD 193
Query: 606 E---SGPWDVTAL 635
+ SG WD+ AL
Sbjct: 194 DFTPSGEWDIVAL 206
>X68275-1|CAA48336.1| 451|Homo sapiens nicotinic receptor beta 4
subunit protein.
Length = 451
Score = 74.5 bits (175), Expect = 5e-13
Identities = 47/153 (30%), Positives = 73/153 (47%), Gaps = 6/153 (3%)
Frame = +3
Query: 195 IVVNLTLHLRHA-NIRESESTVRIQADLQMNWIDKRLSWNAGGV-GCSTWLVSSERLWRP 368
I + L L L ++ E + + L+ W D RL+WN+ G + + ++R+W P
Sbjct: 7 ISIKLQLSLAQLISVNERDEIMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLP 66
Query: 369 DVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 545
D+VL N A T V +NGSV W+ + +++ +P D Q CT KF S
Sbjct: 67 DIVLYNNADGTYEVSVYTNLIVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRS 126
Query: 546 RMHTSDEMDFVIDKRIYSMFE---SGPWDVTAL 635
+ E+D V+ SM + SG WD+ AL
Sbjct: 127 WTYDHTEIDMVLMTPTASMDDFTPSGEWDIVAL 159
>Y08419-1|CAA69696.1| 468|Homo sapiens nicotinic acetylcholine
receptor alpha5 subunit precursor protein.
Length = 468
Score = 70.5 bits (165), Expect = 8e-12
Identities = 43/175 (24%), Positives = 81/175 (46%), Gaps = 11/175 (6%)
Frame = +3
Query: 141 MIDSLLATYDRDSPP----DSKIVVNLTLHLRH-ANIRESESTVRIQADLQMNWIDKRLS 305
++ L Y+R P + KI + L + ++ E + L+ WID +L
Sbjct: 50 LLKDLFQDYERWVRPVEHLNDKIKIKFGLAISQLVDVDEKNQLMTTNVWLKQEWIDVKLR 109
Query: 306 WNAGGVG-CSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVSWIKRLDISTP 482
WN G V S+ +W PD+VL + A + + + NG+V+W + +
Sbjct: 110 WNPDDYGGIKVIRVPSDSVWTPDIVLFDNADGRFEGTSTKTVIRYNGTVTWTPPANYKSS 169
Query: 483 ISMQLDNWPNDMQTCTFKFGSRMHTSDEMDFV-----IDKRIYSMFESGPWDVTA 632
++ + +P D+Q C+ KFGS + ++D + +DKR F++G W++ +
Sbjct: 170 CTIDVTFFPFDLQNCSMKFGSWTYDGSQVDIILEDQDVDKR--DFFDNGEWEIVS 222
>U62434-1|AAB40112.1| 468|Homo sapiens nicotinic acetylcholine
receptor alpha5 subunit precursor protein.
Length = 468
Score = 70.5 bits (165), Expect = 8e-12
Identities = 43/175 (24%), Positives = 81/175 (46%), Gaps = 11/175 (6%)
Frame = +3
Query: 141 MIDSLLATYDRDSPP----DSKIVVNLTLHLRH-ANIRESESTVRIQADLQMNWIDKRLS 305
++ L Y+R P + KI + L + ++ E + L+ WID +L
Sbjct: 50 LLKDLFQDYERWVRPVEHLNDKIKIKFGLAISQLVDVDEKNQLMTTNVWLKQEWIDVKLR 109
Query: 306 WNAGGVG-CSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVSWIKRLDISTP 482
WN G V S+ +W PD+VL + A + + + NG+V+W + +
Sbjct: 110 WNPDDYGGIKVIRVPSDSVWTPDIVLFDNADGRFEGTSTKTVIRYNGTVTWTPPANYKSS 169
Query: 483 ISMQLDNWPNDMQTCTFKFGSRMHTSDEMDFV-----IDKRIYSMFESGPWDVTA 632
++ + +P D+Q C+ KFGS + ++D + +DKR F++G W++ +
Sbjct: 170 CTIDVTFFPFDLQNCSMKFGSWTYDGSQVDIILEDQDVDKR--DFFDNGEWEIVS 222
>BC033639-1|AAH33639.1| 468|Homo sapiens cholinergic receptor,
nicotinic, alpha 5 protein.
Length = 468
Score = 70.5 bits (165), Expect = 8e-12
Identities = 43/175 (24%), Positives = 81/175 (46%), Gaps = 11/175 (6%)
Frame = +3
Query: 141 MIDSLLATYDRDSPP----DSKIVVNLTLHLRH-ANIRESESTVRIQADLQMNWIDKRLS 305
++ L Y+R P + KI + L + ++ E + L+ WID +L
Sbjct: 50 LLKDLFQDYERWVRPVEHLNDKIKIKFGLAISQLVDVDEKNQLMTTNVWLKQEWIDVKLR 109
Query: 306 WNAGGVG-CSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVSWIKRLDISTP 482
WN G V S+ +W PD+VL + A + + + NG+V+W + +
Sbjct: 110 WNPDDYGGIKVIRVPSDSVWTPDIVLFDNADGRFEGTSTKTVIRYNGTVTWTPPANYKSS 169
Query: 483 ISMQLDNWPNDMQTCTFKFGSRMHTSDEMDFV-----IDKRIYSMFESGPWDVTA 632
++ + +P D+Q C+ KFGS + ++D + +DKR F++G W++ +
Sbjct: 170 CTIDVTFFPFDLQNCSMKFGSWTYDGSQVDIILEDQDVDKR--DFFDNGEWEIVS 222
>AJ306481-1|CAC34820.1| 468|Homo sapiens neuronal nicotinic
acetylcholine receptor alpha-5subunit protein.
Length = 468
Score = 70.5 bits (165), Expect = 8e-12
Identities = 43/175 (24%), Positives = 81/175 (46%), Gaps = 11/175 (6%)
Frame = +3
Query: 141 MIDSLLATYDRDSPP----DSKIVVNLTLHLRH-ANIRESESTVRIQADLQMNWIDKRLS 305
++ L Y+R P + KI + L + ++ E + L+ WID +L
Sbjct: 50 LLKDLFQDYERWVRPVEHLNDKIKIKFGLAISQLVDVDEKNQLMTTNVWLKQEWIDVKLR 109
Query: 306 WNAGGVG-CSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVSWIKRLDISTP 482
WN G V S+ +W PD+VL + A + + + NG+V+W + +
Sbjct: 110 WNPDDYGGIKVIRVPSDSVWTPDIVLFDNADGRFEGTSTKTVIRYNGTVTWTPPANYKSS 169
Query: 483 ISMQLDNWPNDMQTCTFKFGSRMHTSDEMDFV-----IDKRIYSMFESGPWDVTA 632
++ + +P D+Q C+ KFGS + ++D + +DKR F++G W++ +
Sbjct: 170 CTIDVTFFPFDLQNCSMKFGSWTYDGSQVDIILEDQDVDKR--DFFDNGEWEIVS 222
>M86383-1|AAC84176.1| 502|Homo sapiens nicotinic acetylcholine
receptor alpha 3 subunit precursor protein.
Length = 502
Score = 69.3 bits (162), Expect = 2e-11
Identities = 38/126 (30%), Positives = 65/126 (51%), Gaps = 8/126 (6%)
Frame = +3
Query: 273 LQMNWIDKRLSWNAGGVGCSTWL-VSSERLWRPDVVLLNAAATTAGDYAL----RARVSN 437
L+ W D +L WN G G + ++ V ++++W+PD+VL N A GD+ + +A +
Sbjct: 84 LKQIWNDYKLKWNPSGYGGAEFMRVPAQKIWKPDIVLYNNAV---GDFQVTTKTKALLKY 140
Query: 438 NGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHTSDEMDFVI---DKRIYSMFE 608
G V+WI + + + +P D Q CT KFGS + ++D V+ + +E
Sbjct: 141 TGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVLIGSSMNLKDYWE 200
Query: 609 SGPWDV 626
SG W +
Sbjct: 201 SGEWAI 206
>M83712-1|AAA58357.1| 468|Homo sapiens nicotinic receptor alpha 5
subunit protein.
Length = 468
Score = 69.3 bits (162), Expect = 2e-11
Identities = 43/175 (24%), Positives = 80/175 (45%), Gaps = 11/175 (6%)
Frame = +3
Query: 141 MIDSLLATYDRDSPP----DSKIVVNLTLHLRH-ANIRESESTVRIQADLQMNWIDKRLS 305
++ L Y+R P + KI + L + ++ E + L+ WID +L
Sbjct: 50 LLKDLFQDYERWVRPVEHLNDKIKIKFGLAISQLVDVDEKNQLMTTNVWLKQEWIDVKLR 109
Query: 306 WNAGGVG-CSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVSWIKRLDISTP 482
WN G V S+ W PD+VL + A + + + NG+V+W + +
Sbjct: 110 WNPDDYGGIKVIRVPSDSSWTPDIVLFDNADGRFEGTSTKTVIRYNGTVTWTPPANYKSS 169
Query: 483 ISMQLDNWPNDMQTCTFKFGSRMHTSDEMDFV-----IDKRIYSMFESGPWDVTA 632
++ + +P D+Q C+ KFGS + ++D + +DKR F++G W++ +
Sbjct: 170 CTIDVTFFPFDLQNCSMKFGSWTYDGSQVDIILEDQDVDKR--DFFDNGEWEIVS 222
>Y08417-1|CAA69694.1| 458|Homo sapiens nicotinic acetylcholine
receptor beta3 subunit precursor protein.
Length = 458
Score = 68.9 bits (161), Expect = 2e-11
Identities = 39/137 (28%), Positives = 64/137 (46%), Gaps = 5/137 (3%)
Frame = +3
Query: 231 NIRESESTVRIQADLQMNWIDKRLSWNAGGVG-CSTWLVSSERLWRPDVVLL-NAAATTA 404
++ E + L+ W D +L WN G + V SE LW PD+VL NA
Sbjct: 67 DVDEKNQLMTTNVWLKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFE 126
Query: 405 GDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHTSDEMDFV-I 581
G + V +NG+V W + +M + +P D Q C+ KFGS + +D + I
Sbjct: 127 GSLMTKVIVKSNGTVVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGTMVDLILI 186
Query: 582 DKRI--YSMFESGPWDV 626
++ + F++G W++
Sbjct: 187 NENVDRKDFFDNGEWEI 203
>X67513-1|CAA47851.1| 423|Homo sapiens nicotinic acetylcholine
receptor beta-3 subunit protein.
Length = 423
Score = 68.9 bits (161), Expect = 2e-11
Identities = 39/137 (28%), Positives = 64/137 (46%), Gaps = 5/137 (3%)
Frame = +3
Query: 231 NIRESESTVRIQADLQMNWIDKRLSWNAGGVG-CSTWLVSSERLWRPDVVLL-NAAATTA 404
++ E + L+ W D +L WN G + V SE LW PD+VL NA
Sbjct: 32 DVDEKNQLMTTNVWLKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFE 91
Query: 405 GDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHTSDEMDFV-I 581
G + V +NG+V W + +M + +P D Q C+ KFGS + +D + I
Sbjct: 92 GSLMTKVIVKSNGTVVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGTMVDLILI 151
Query: 582 DKRI--YSMFESGPWDV 626
++ + F++G W++
Sbjct: 152 NENVDRKDFFDNGEWEI 168
>U62438-1|AAB40116.1| 458|Homo sapiens nicotinic acetylcholine
receptor beta3 subunit precursor protein.
Length = 458
Score = 68.9 bits (161), Expect = 2e-11
Identities = 39/137 (28%), Positives = 64/137 (46%), Gaps = 5/137 (3%)
Frame = +3
Query: 231 NIRESESTVRIQADLQMNWIDKRLSWNAGGVG-CSTWLVSSERLWRPDVVLL-NAAATTA 404
++ E + L+ W D +L WN G + V SE LW PD+VL NA
Sbjct: 67 DVDEKNQLMTTNVWLKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFE 126
Query: 405 GDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHTSDEMDFV-I 581
G + V +NG+V W + +M + +P D Q C+ KFGS + +D + I
Sbjct: 127 GSLMTKVIVKSNGTVVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGTMVDLILI 186
Query: 582 DKRI--YSMFESGPWDV 626
++ + F++G W++
Sbjct: 187 NENVDRKDFFDNGEWEI 203
>BC069788-1|AAH69788.1| 458|Homo sapiens cholinergic receptor,
nicotinic, beta 3 protein.
Length = 458
Score = 68.9 bits (161), Expect = 2e-11
Identities = 39/137 (28%), Positives = 64/137 (46%), Gaps = 5/137 (3%)
Frame = +3
Query: 231 NIRESESTVRIQADLQMNWIDKRLSWNAGGVG-CSTWLVSSERLWRPDVVLL-NAAATTA 404
++ E + L+ W D +L WN G + V SE LW PD+VL NA
Sbjct: 67 DVDEKNQLMTTNVWLKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFE 126
Query: 405 GDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHTSDEMDFV-I 581
G + V +NG+V W + +M + +P D Q C+ KFGS + +D + I
Sbjct: 127 GSLMTKVIVKSNGTVVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGTMVDLILI 186
Query: 582 DKRI--YSMFESGPWDV 626
++ + F++G W++
Sbjct: 187 NENVDRKDFFDNGEWEI 203
>BC069703-1|AAH69703.1| 458|Homo sapiens cholinergic receptor,
nicotinic, beta 3 protein.
Length = 458
Score = 68.9 bits (161), Expect = 2e-11
Identities = 39/137 (28%), Positives = 64/137 (46%), Gaps = 5/137 (3%)
Frame = +3
Query: 231 NIRESESTVRIQADLQMNWIDKRLSWNAGGVG-CSTWLVSSERLWRPDVVLL-NAAATTA 404
++ E + L+ W D +L WN G + V SE LW PD+VL NA
Sbjct: 67 DVDEKNQLMTTNVWLKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFE 126
Query: 405 GDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHTSDEMDFV-I 581
G + V +NG+V W + +M + +P D Q C+ KFGS + +D + I
Sbjct: 127 GSLMTKVIVKSNGTVVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGTMVDLILI 186
Query: 582 DKRI--YSMFESGPWDV 626
++ + F++G W++
Sbjct: 187 NENVDRKDFFDNGEWEI 203
>BC069681-1|AAH69681.1| 458|Homo sapiens cholinergic receptor,
nicotinic, beta 3 protein.
Length = 458
Score = 68.9 bits (161), Expect = 2e-11
Identities = 39/137 (28%), Positives = 64/137 (46%), Gaps = 5/137 (3%)
Frame = +3
Query: 231 NIRESESTVRIQADLQMNWIDKRLSWNAGGVG-CSTWLVSSERLWRPDVVLL-NAAATTA 404
++ E + L+ W D +L WN G + V SE LW PD+VL NA
Sbjct: 67 DVDEKNQLMTTNVWLKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFE 126
Query: 405 GDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHTSDEMDFV-I 581
G + V +NG+V W + +M + +P D Q C+ KFGS + +D + I
Sbjct: 127 GSLMTKVIVKSNGTVVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGTMVDLILI 186
Query: 582 DKRI--YSMFESGPWDV 626
++ + F++G W++
Sbjct: 187 NENVDRKDFFDNGEWEI 203
>AF140765-1|AAD33063.1| 458|Homo sapiens neuronal acetylcholine
receptor beta-3 subunit precursor protein.
Length = 458
Score = 68.9 bits (161), Expect = 2e-11
Identities = 39/137 (28%), Positives = 64/137 (46%), Gaps = 5/137 (3%)
Frame = +3
Query: 231 NIRESESTVRIQADLQMNWIDKRLSWNAGGVG-CSTWLVSSERLWRPDVVLL-NAAATTA 404
++ E + L+ W D +L WN G + V SE LW PD+VL NA
Sbjct: 67 DVDEKNQLMTTNVWLKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFE 126
Query: 405 GDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHTSDEMDFV-I 581
G + V +NG+V W + +M + +P D Q C+ KFGS + +D + I
Sbjct: 127 GSLMTKVIVKSNGTVVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGTMVDLILI 186
Query: 582 DKRI--YSMFESGPWDV 626
++ + F++G W++
Sbjct: 187 NENVDRKDFFDNGEWEI 203
>Y08415-1|CAA69692.1| 502|Homo sapiens nicotinic acetylcholine
receptor beta2 subunit precursor protein.
Length = 502
Score = 68.1 bits (159), Expect = 4e-11
Identities = 44/153 (28%), Positives = 70/153 (45%), Gaps = 6/153 (3%)
Frame = +3
Query: 195 IVVNLTLHLRHA-NIRESESTVRIQADLQMNWIDKRLSWNAGGV-GCSTWLVSSERLWRP 368
+ V L + L ++ E E + L W D RL+W + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 369 DVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 545
DVVL N A + A VS +GS+ W+ + +++ ++P D Q CT KF S
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRS 175
Query: 546 RMHTSDEMDFVIDKRIYSMFE---SGPWDVTAL 635
+ E+D V+ + S+ + SG WD+ AL
Sbjct: 176 WTYDRTEIDLVLKSEVASLDDFTPSGEWDIVAL 208
>X53179-1|CAA37320.1| 502|Homo sapiens precursor peptide (AA -25 to
477) protein.
Length = 502
Score = 68.1 bits (159), Expect = 4e-11
Identities = 44/153 (28%), Positives = 70/153 (45%), Gaps = 6/153 (3%)
Frame = +3
Query: 195 IVVNLTLHLRHA-NIRESESTVRIQADLQMNWIDKRLSWNAGGV-GCSTWLVSSERLWRP 368
+ V L + L ++ E E + L W D RL+W + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 369 DVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 545
DVVL N A + A VS +GS+ W+ + +++ ++P D Q CT KF S
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRS 175
Query: 546 RMHTSDEMDFVIDKRIYSMFE---SGPWDVTAL 635
+ E+D V+ + S+ + SG WD+ AL
Sbjct: 176 WTYDRTEIDLVLKSEVASLDDFTPSGEWDIVAL 208
>U62437-1|AAB40115.1| 502|Homo sapiens nicotinic acetylcholine
receptor beta2 subunit precursor protein.
Length = 502
Score = 68.1 bits (159), Expect = 4e-11
Identities = 44/153 (28%), Positives = 70/153 (45%), Gaps = 6/153 (3%)
Frame = +3
Query: 195 IVVNLTLHLRHA-NIRESESTVRIQADLQMNWIDKRLSWNAGGV-GCSTWLVSSERLWRP 368
+ V L + L ++ E E + L W D RL+W + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 369 DVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 545
DVVL N A + A VS +GS+ W+ + +++ ++P D Q CT KF S
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRS 175
Query: 546 RMHTSDEMDFVIDKRIYSMFE---SGPWDVTAL 635
+ E+D V+ + S+ + SG WD+ AL
Sbjct: 176 WTYDRTEIDLVLKSEVASLDDFTPSGEWDIVAL 208
>BC075041-1|AAH75041.1| 502|Homo sapiens cholinergic receptor,
nicotinic, beta 2 (neuronal) protein.
Length = 502
Score = 68.1 bits (159), Expect = 4e-11
Identities = 44/153 (28%), Positives = 70/153 (45%), Gaps = 6/153 (3%)
Frame = +3
Query: 195 IVVNLTLHLRHA-NIRESESTVRIQADLQMNWIDKRLSWNAGGV-GCSTWLVSSERLWRP 368
+ V L + L ++ E E + L W D RL+W + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 369 DVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 545
DVVL N A + A VS +GS+ W+ + +++ ++P D Q CT KF S
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRS 175
Query: 546 RMHTSDEMDFVIDKRIYSMFE---SGPWDVTAL 635
+ E+D V+ + S+ + SG WD+ AL
Sbjct: 176 WTYDRTEIDLVLKSEVASLDDFTPSGEWDIVAL 208
>BC075040-1|AAH75040.1| 502|Homo sapiens cholinergic receptor,
nicotinic, beta 2 (neuronal) protein.
Length = 502
Score = 68.1 bits (159), Expect = 4e-11
Identities = 44/153 (28%), Positives = 70/153 (45%), Gaps = 6/153 (3%)
Frame = +3
Query: 195 IVVNLTLHLRHA-NIRESESTVRIQADLQMNWIDKRLSWNAGGV-GCSTWLVSSERLWRP 368
+ V L + L ++ E E + L W D RL+W + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 369 DVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 545
DVVL N A + A VS +GS+ W+ + +++ ++P D Q CT KF S
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRS 175
Query: 546 RMHTSDEMDFVIDKRIYSMFE---SGPWDVTAL 635
+ E+D V+ + S+ + SG WD+ AL
Sbjct: 176 WTYDRTEIDLVLKSEVASLDDFTPSGEWDIVAL 208
>AL592078-3|CAI16184.1| 502|Homo sapiens cholinergic receptor,
nicotinic, beta 2 (neuronal) protein.
Length = 502
Score = 68.1 bits (159), Expect = 4e-11
Identities = 44/153 (28%), Positives = 70/153 (45%), Gaps = 6/153 (3%)
Frame = +3
Query: 195 IVVNLTLHLRHA-NIRESESTVRIQADLQMNWIDKRLSWNAGGV-GCSTWLVSSERLWRP 368
+ V L + L ++ E E + L W D RL+W + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 369 DVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 545
DVVL N A + A VS +GS+ W+ + +++ ++P D Q CT KF S
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRS 175
Query: 546 RMHTSDEMDFVIDKRIYSMFE---SGPWDVTAL 635
+ E+D V+ + S+ + SG WD+ AL
Sbjct: 176 WTYDRTEIDLVLKSEVASLDDFTPSGEWDIVAL 208
>AJ001935-1|CAA05108.1| 504|Homo sapiens CHRNB2 protein.
Length = 504
Score = 68.1 bits (159), Expect = 4e-11
Identities = 44/153 (28%), Positives = 70/153 (45%), Gaps = 6/153 (3%)
Frame = +3
Query: 195 IVVNLTLHLRHA-NIRESESTVRIQADLQMNWIDKRLSWNAGGV-GCSTWLVSSERLWRP 368
+ V L + L ++ E E + L W D RL+W + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 369 DVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 545
DVVL N A + A VS +GS+ W+ + +++ ++P D Q CT KF S
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRS 175
Query: 546 RMHTSDEMDFVIDKRIYSMFE---SGPWDVTAL 635
+ E+D V+ + S+ + SG WD+ AL
Sbjct: 176 WTYDRTEIDLVLKSEVASLDDFTPSGEWDIVAL 208
>AF077186-1|AAD45422.1| 502|Homo sapiens neuronal nicotinic
acetylcholine receptor beta 2 protein.
Length = 502
Score = 68.1 bits (159), Expect = 4e-11
Identities = 44/153 (28%), Positives = 70/153 (45%), Gaps = 6/153 (3%)
Frame = +3
Query: 195 IVVNLTLHLRHA-NIRESESTVRIQADLQMNWIDKRLSWNAGGV-GCSTWLVSSERLWRP 368
+ V L + L ++ E E + L W D RL+W + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 369 DVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 545
DVVL N A + A VS +GS+ W+ + +++ ++P D Q CT KF S
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRS 175
Query: 546 RMHTSDEMDFVIDKRIYSMFE---SGPWDVTAL 635
+ E+D V+ + S+ + SG WD+ AL
Sbjct: 176 WTYDRTEIDLVLKSEVASLDDFTPSGEWDIVAL 208
>Y08418-1|CAA69695.1| 503|Homo sapiens nicotinic acetylcholine
receptor alpha3 subunit precursor protein.
Length = 503
Score = 67.3 bits (157), Expect = 7e-11
Identities = 36/123 (29%), Positives = 61/123 (49%), Gaps = 5/123 (4%)
Frame = +3
Query: 273 LQMNWIDKRLSWNAGGVGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 446
L+ W D +L WN G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 85 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 144
Query: 447 VSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHTSDEMDFVI---DKRIYSMFESGP 617
V+WI + + + +P D Q CT KFGS + ++D V+ + +ESG
Sbjct: 145 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVLIGSSMNLKDYWESGE 204
Query: 618 WDV 626
W +
Sbjct: 205 WAI 207
>X53559-1|CAA37625.1| 474|Homo sapiens neuronal nicotinic
acetylcholine receptor alpha-3merase protein.
Length = 474
Score = 67.3 bits (157), Expect = 7e-11
Identities = 36/123 (29%), Positives = 61/123 (49%), Gaps = 5/123 (4%)
Frame = +3
Query: 273 LQMNWIDKRLSWNAGGVGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 446
L+ W D +L WN G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 56 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 115
Query: 447 VSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHTSDEMDFVI---DKRIYSMFESGP 617
V+WI + + + +P D Q CT KFGS + ++D V+ + +ESG
Sbjct: 116 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVLIGSSMNLKDYWESGE 175
Query: 618 WDV 626
W +
Sbjct: 176 WAI 178
>U62432-1|AAB40110.1| 504|Homo sapiens nicotinic acetylcholine
receptor alpha3 subunit precursor protein.
Length = 504
Score = 67.3 bits (157), Expect = 7e-11
Identities = 36/123 (29%), Positives = 61/123 (49%), Gaps = 5/123 (4%)
Frame = +3
Query: 273 LQMNWIDKRLSWNAGGVGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 446
L+ W D +L WN G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 86 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 145
Query: 447 VSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHTSDEMDFVI---DKRIYSMFESGP 617
V+WI + + + +P D Q CT KFGS + ++D V+ + +ESG
Sbjct: 146 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVLIGSSMNLKDYWESGE 205
Query: 618 WDV 626
W +
Sbjct: 206 WAI 208
>M37981-1|AAA59942.1| 503|Homo sapiens neuronal nicotinic
acetylcholine receptor protein.
Length = 503
Score = 67.3 bits (157), Expect = 7e-11
Identities = 36/123 (29%), Positives = 61/123 (49%), Gaps = 5/123 (4%)
Frame = +3
Query: 273 LQMNWIDKRLSWNAGGVGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 446
L+ W D +L WN G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 85 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 144
Query: 447 VSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHTSDEMDFVI---DKRIYSMFESGP 617
V+WI + + + +P D Q CT KFGS + ++D V+ + +ESG
Sbjct: 145 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVLIGSSMNLKDYWESGE 204
Query: 618 WDV 626
W +
Sbjct: 205 WAI 207
>BT006897-1|AAP35543.1| 505|Homo sapiens cholinergic receptor,
nicotinic, alpha polypeptide 3 protein.
Length = 505
Score = 67.3 bits (157), Expect = 7e-11
Identities = 36/123 (29%), Positives = 61/123 (49%), Gaps = 5/123 (4%)
Frame = +3
Query: 273 LQMNWIDKRLSWNAGGVGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 446
L+ W D +L WN G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 87 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 146
Query: 447 VSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHTSDEMDFVI---DKRIYSMFESGP 617
V+WI + + + +P D Q CT KFGS + ++D V+ + +ESG
Sbjct: 147 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVLIGSSMNLKDYWESGE 206
Query: 618 WDV 626
W +
Sbjct: 207 WAI 209
>BT006646-1|AAP35292.1| 489|Homo sapiens cholinergic receptor,
nicotinic, alpha polypeptide 3 protein.
Length = 489
Score = 67.3 bits (157), Expect = 7e-11
Identities = 36/123 (29%), Positives = 61/123 (49%), Gaps = 5/123 (4%)
Frame = +3
Query: 273 LQMNWIDKRLSWNAGGVGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 446
L+ W D +L WN G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 87 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 146
Query: 447 VSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHTSDEMDFVI---DKRIYSMFESGP 617
V+WI + + + +P D Q CT KFGS + ++D V+ + +ESG
Sbjct: 147 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVLIGSSMNLKDYWESGE 206
Query: 618 WDV 626
W +
Sbjct: 207 WAI 209
>BC098443-1|AAH98443.1| 504|Homo sapiens cholinergic receptor,
nicotinic, alpha 3 protein.
Length = 504
Score = 67.3 bits (157), Expect = 7e-11
Identities = 36/123 (29%), Positives = 61/123 (49%), Gaps = 5/123 (4%)
Frame = +3
Query: 273 LQMNWIDKRLSWNAGGVGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 446
L+ W D +L WN G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 86 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 145
Query: 447 VSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHTSDEMDFVI---DKRIYSMFESGP 617
V+WI + + + +P D Q CT KFGS + ++D V+ + +ESG
Sbjct: 146 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVLIGSSMNLKDYWESGE 205
Query: 618 WDV 626
W +
Sbjct: 206 WAI 208
>BC006114-1|AAH06114.1| 489|Homo sapiens CHRNA3 protein protein.
Length = 489
Score = 67.3 bits (157), Expect = 7e-11
Identities = 36/123 (29%), Positives = 61/123 (49%), Gaps = 5/123 (4%)
Frame = +3
Query: 273 LQMNWIDKRLSWNAGGVGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 446
L+ W D +L WN G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 87 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 146
Query: 447 VSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHTSDEMDFVI---DKRIYSMFESGP 617
V+WI + + + +P D Q CT KFGS + ++D V+ + +ESG
Sbjct: 147 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVLIGSSMNLKDYWESGE 206
Query: 618 WDV 626
W +
Sbjct: 207 WAI 209
>BC002996-1|AAH02996.1| 505|Homo sapiens cholinergic receptor,
nicotinic, alpha 3 protein.
Length = 505
Score = 67.3 bits (157), Expect = 7e-11
Identities = 36/123 (29%), Positives = 61/123 (49%), Gaps = 5/123 (4%)
Frame = +3
Query: 273 LQMNWIDKRLSWNAGGVGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 446
L+ W D +L WN G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 87 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 146
Query: 447 VSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHTSDEMDFVI---DKRIYSMFESGP 617
V+WI + + + +P D Q CT KFGS + ++D V+ + +ESG
Sbjct: 147 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVLIGSSMNLKDYWESGE 206
Query: 618 WDV 626
W +
Sbjct: 207 WAI 209
>BC001642-1|AAH01642.1| 505|Homo sapiens cholinergic receptor,
nicotinic, alpha 3 protein.
Length = 505
Score = 67.3 bits (157), Expect = 7e-11
Identities = 36/123 (29%), Positives = 61/123 (49%), Gaps = 5/123 (4%)
Frame = +3
Query: 273 LQMNWIDKRLSWNAGGVGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 446
L+ W D +L WN G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 87 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 146
Query: 447 VSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHTSDEMDFVI---DKRIYSMFESGP 617
V+WI + + + +P D Q CT KFGS + ++D V+ + +ESG
Sbjct: 147 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVLIGSSMNLKDYWESGE 206
Query: 618 WDV 626
W +
Sbjct: 207 WAI 209
>BC000513-1|AAH00513.1| 505|Homo sapiens cholinergic receptor,
nicotinic, alpha 3 protein.
Length = 505
Score = 67.3 bits (157), Expect = 7e-11
Identities = 36/123 (29%), Positives = 61/123 (49%), Gaps = 5/123 (4%)
Frame = +3
Query: 273 LQMNWIDKRLSWNAGGVGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 446
L+ W D +L WN G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 87 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 146
Query: 447 VSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHTSDEMDFVI---DKRIYSMFESGP 617
V+WI + + + +P D Q CT KFGS + ++D V+ + +ESG
Sbjct: 147 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVLIGSSMNLKDYWESGE 206
Query: 618 WDV 626
W +
Sbjct: 207 WAI 209
>AJ007783-1|CAA07682.1| 504|Homo sapiens nicotinic acetylcholine
receptor alpha-3 subunit protein.
Length = 504
Score = 67.3 bits (157), Expect = 7e-11
Identities = 36/123 (29%), Positives = 61/123 (49%), Gaps = 5/123 (4%)
Frame = +3
Query: 273 LQMNWIDKRLSWNAGGVGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 446
L+ W D +L WN G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 86 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 145
Query: 447 VSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHTSDEMDFVI---DKRIYSMFESGP 617
V+WI + + + +P D Q CT KFGS + ++D V+ + +ESG
Sbjct: 146 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVLIGSSMNLKDYWESGE 205
Query: 618 WDV 626
W +
Sbjct: 206 WAI 208
>AF385584-1|AAK68110.1| 489|Homo sapiens nicotinic cholinergic
receptor alpha 3 protein.
Length = 489
Score = 67.3 bits (157), Expect = 7e-11
Identities = 36/123 (29%), Positives = 61/123 (49%), Gaps = 5/123 (4%)
Frame = +3
Query: 273 LQMNWIDKRLSWNAGGVGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 446
L+ W D +L WN G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 81 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 140
Query: 447 VSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHTSDEMDFVI---DKRIYSMFESGP 617
V+WI + + + +P D Q CT KFGS + ++D V+ + +ESG
Sbjct: 141 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVLIGSSMNLKDYWESGE 200
Query: 618 WDV 626
W +
Sbjct: 201 WAI 203
>Y16281-1|CAA76154.1| 529|Homo sapiens nicotinic acetylcholine
receptor alpha2 subunit precursor protein.
Length = 529
Score = 65.7 bits (153), Expect = 2e-10
Identities = 41/139 (29%), Positives = 66/139 (47%), Gaps = 7/139 (5%)
Frame = +3
Query: 231 NIRESESTVRIQADLQMNWIDKRLSWNAGGVGCSTWL-VSSERLWRPDVVLLNAA-ATTA 404
++ E + L+ W D +L WN G T L V SE +W PD+VL N A A
Sbjct: 97 DVDEKNQMMTTNVWLKQEWSDYKLRWNPADFGNITSLRVPSEMIWIPDIVLYNNADGEFA 156
Query: 405 GDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHTS-----DEM 569
+ +A + + G+V W+ + S+ + +P D Q C KFGS + ++M
Sbjct: 157 VTHMTKAHLFSTGTVHWVPPAIYKSSCSIDVTFFPFDQQNCKMKFGSWTYDKAKIDLEQM 216
Query: 570 DFVIDKRIYSMFESGPWDV 626
+ +D + Y +ESG W +
Sbjct: 217 EQTVDLKDY--WESGEWAI 233
>U62431-1|AAB40109.1| 529|Homo sapiens nicotinic acetylcholine
receptor alpha2 subunit precursor protein.
Length = 529
Score = 65.7 bits (153), Expect = 2e-10
Identities = 41/139 (29%), Positives = 66/139 (47%), Gaps = 7/139 (5%)
Frame = +3
Query: 231 NIRESESTVRIQADLQMNWIDKRLSWNAGGVGCSTWL-VSSERLWRPDVVLLNAA-ATTA 404
++ E + L+ W D +L WN G T L V SE +W PD+VL N A A
Sbjct: 97 DVDEKNQMMTTNVWLKQEWSDYKLRWNPADFGNITSLRVPSEMIWIPDIVLYNNADGEFA 156
Query: 405 GDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHTS-----DEM 569
+ +A + + G+V W+ + S+ + +P D Q C KFGS + ++M
Sbjct: 157 VTHMTKAHLFSTGTVHWVPPAIYKSSCSIDVTFFPFDQQNCKMKFGSWTYDKAKIDLEQM 216
Query: 570 DFVIDKRIYSMFESGPWDV 626
+ +D + Y +ESG W +
Sbjct: 217 EQTVDLKDY--WESGEWAI 233
>Y08421-1|CAA69698.1| 627|Homo sapiens nicotinic acetylcholine
receptor alpha4 subunit precursor protein.
Length = 627
Score = 63.3 bits (147), Expect = 1e-09
Identities = 49/173 (28%), Positives = 83/173 (47%), Gaps = 13/173 (7%)
Frame = +3
Query: 141 MIDSLLATYDRDSPPDSKI--VVNLTLHLRHA---NIRESESTVRIQADLQMNWIDKRLS 305
++ L + Y++ S P + I VV + L A ++ E + ++ W D +L
Sbjct: 40 LLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLR 99
Query: 306 WNAGGVGCSTWL-VSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNGSVSWIKRLD 470
W+ T + + SE +WRPD+VL N A GD+A+ +A + ++G V W
Sbjct: 100 WDPADYENVTSIRIPSELIWRPDIVLYNNAD---GDFAVTHLTKAHLFHDGRVQWTPPAI 156
Query: 471 ISTPISMQLDNWPNDMQTCTFKFGSRMHTSDEMDFV-IDKRI--YSMFESGPW 620
+ S+ + +P D Q CT KFGS + ++D V + R+ +ESG W
Sbjct: 157 YKSSCSIDVTFFPFDQQNCTMKFGSWTYDKAKIDLVNMHSRVDQLDFWESGEW 209
>X89741-1|CAA61893.1| 627|Homo sapiens neuronal acetylcholine
receptor alpha-4 subunit protein.
Length = 627
Score = 63.3 bits (147), Expect = 1e-09
Identities = 49/173 (28%), Positives = 83/173 (47%), Gaps = 13/173 (7%)
Frame = +3
Query: 141 MIDSLLATYDRDSPPDSKI--VVNLTLHLRHA---NIRESESTVRIQADLQMNWIDKRLS 305
++ L + Y++ S P + I VV + L A ++ E + ++ W D +L
Sbjct: 40 LLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLR 99
Query: 306 WNAGGVGCSTWL-VSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNGSVSWIKRLD 470
W+ T + + SE +WRPD+VL N A GD+A+ +A + ++G V W
Sbjct: 100 WDPADYENVTSIRIPSELIWRPDIVLYNNAD---GDFAVTHLTKAHLFHDGRVQWTPPAI 156
Query: 471 ISTPISMQLDNWPNDMQTCTFKFGSRMHTSDEMDFV-IDKRI--YSMFESGPW 620
+ S+ + +P D Q CT KFGS + ++D V + R+ +ESG W
Sbjct: 157 YKSSCSIDVTFFPFDQQNCTMKFGSWTYDKAKIDLVNMHSRVDQLDFWESGEW 209
>X87629-1|CAA60959.1| 602|Homo sapiens nicotinic acetylcholine
receptor protein.
Length = 602
Score = 63.3 bits (147), Expect = 1e-09
Identities = 49/173 (28%), Positives = 83/173 (47%), Gaps = 13/173 (7%)
Frame = +3
Query: 141 MIDSLLATYDRDSPPDSKI--VVNLTLHLRHA---NIRESESTVRIQADLQMNWIDKRLS 305
++ L + Y++ S P + I VV + L A ++ E + ++ W D +L
Sbjct: 15 LLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLR 74
Query: 306 WNAGGVGCSTWL-VSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNGSVSWIKRLD 470
W+ T + + SE +WRPD+VL N A GD+A+ +A + ++G V W
Sbjct: 75 WDPADYENVTSIRIPSELIWRPDIVLYNNAD---GDFAVTHLTKAHLFHDGRVQWTPPAI 131
Query: 471 ISTPISMQLDNWPNDMQTCTFKFGSRMHTSDEMDFV-IDKRI--YSMFESGPW 620
+ S+ + +P D Q CT KFGS + ++D V + R+ +ESG W
Sbjct: 132 YKSSCSIDVTFFPFDQQNCTMKFGSWTYDKAKIDLVNMHSRVDQLDFWESGEW 184
>U62433-1|AAB40111.1| 627|Homo sapiens nicotinic acetylcholine
receptor alpha4 subunit precursor protein.
Length = 627
Score = 63.3 bits (147), Expect = 1e-09
Identities = 49/173 (28%), Positives = 83/173 (47%), Gaps = 13/173 (7%)
Frame = +3
Query: 141 MIDSLLATYDRDSPPDSKI--VVNLTLHLRHA---NIRESESTVRIQADLQMNWIDKRLS 305
++ L + Y++ S P + I VV + L A ++ E + ++ W D +L
Sbjct: 40 LLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLR 99
Query: 306 WNAGGVGCSTWL-VSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNGSVSWIKRLD 470
W+ T + + SE +WRPD+VL N A GD+A+ +A + ++G V W
Sbjct: 100 WDPADYENVTSIRIPSELIWRPDIVLYNNAD---GDFAVTHLTKAHLFHDGRVQWTPPAI 156
Query: 471 ISTPISMQLDNWPNDMQTCTFKFGSRMHTSDEMDFV-IDKRI--YSMFESGPW 620
+ S+ + +P D Q CT KFGS + ++D V + R+ +ESG W
Sbjct: 157 YKSSCSIDVTFFPFDQQNCTMKFGSWTYDKAKIDLVNMHSRVDQLDFWESGEW 209
>L35901-1|AAA64743.1| 627|Homo sapiens nicotinic acetylcholine
receptor alpha 4 subunit protein.
Length = 627
Score = 63.3 bits (147), Expect = 1e-09
Identities = 49/173 (28%), Positives = 83/173 (47%), Gaps = 13/173 (7%)
Frame = +3
Query: 141 MIDSLLATYDRDSPPDSKI--VVNLTLHLRHA---NIRESESTVRIQADLQMNWIDKRLS 305
++ L + Y++ S P + I VV + L A ++ E + ++ W D +L
Sbjct: 40 LLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLR 99
Query: 306 WNAGGVGCSTWL-VSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNGSVSWIKRLD 470
W+ T + + SE +WRPD+VL N A GD+A+ +A + ++G V W
Sbjct: 100 WDPADYENVTSIRIPSELIWRPDIVLYNNAD---GDFAVTHLTKAHLFHDGRVQWTPPAI 156
Query: 471 ISTPISMQLDNWPNDMQTCTFKFGSRMHTSDEMDFV-IDKRI--YSMFESGPW 620
+ S+ + +P D Q CT KFGS + ++D V + R+ +ESG W
Sbjct: 157 YKSSCSIDVTFFPFDQQNCTMKFGSWTYDKAKIDLVNMHSRVDQLDFWESGEW 209
>DQ093071-1|AAY88737.1| 627|Homo sapiens cholinergic receptor,
nicotinic, alpha polypeptide 4 protein.
Length = 627
Score = 63.3 bits (147), Expect = 1e-09
Identities = 49/173 (28%), Positives = 83/173 (47%), Gaps = 13/173 (7%)
Frame = +3
Query: 141 MIDSLLATYDRDSPPDSKI--VVNLTLHLRHA---NIRESESTVRIQADLQMNWIDKRLS 305
++ L + Y++ S P + I VV + L A ++ E + ++ W D +L
Sbjct: 40 LLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLR 99
Query: 306 WNAGGVGCSTWL-VSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNGSVSWIKRLD 470
W+ T + + SE +WRPD+VL N A GD+A+ +A + ++G V W
Sbjct: 100 WDPADYENVTSIRIPSELIWRPDIVLYNNAD---GDFAVTHLTKAHLFHDGRVQWTPPAI 156
Query: 471 ISTPISMQLDNWPNDMQTCTFKFGSRMHTSDEMDFV-IDKRI--YSMFESGPW 620
+ S+ + +P D Q CT KFGS + ++D V + R+ +ESG W
Sbjct: 157 YKSSCSIDVTFFPFDQQNCTMKFGSWTYDKAKIDLVNMHSRVDQLDFWESGEW 209
>BC096290-1|AAH96290.1| 627|Homo sapiens cholinergic receptor,
nicotinic, alpha 4 protein.
Length = 627
Score = 63.3 bits (147), Expect = 1e-09
Identities = 49/173 (28%), Positives = 83/173 (47%), Gaps = 13/173 (7%)
Frame = +3
Query: 141 MIDSLLATYDRDSPPDSKI--VVNLTLHLRHA---NIRESESTVRIQADLQMNWIDKRLS 305
++ L + Y++ S P + I VV + L A ++ E + ++ W D +L
Sbjct: 40 LLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLR 99
Query: 306 WNAGGVGCSTWL-VSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNGSVSWIKRLD 470
W+ T + + SE +WRPD+VL N A GD+A+ +A + ++G V W
Sbjct: 100 WDPADYENVTSIRIPSELIWRPDIVLYNNAD---GDFAVTHLTKAHLFHDGRVQWTPPAI 156
Query: 471 ISTPISMQLDNWPNDMQTCTFKFGSRMHTSDEMDFV-IDKRI--YSMFESGPW 620
+ S+ + +P D Q CT KFGS + ++D V + R+ +ESG W
Sbjct: 157 YKSSCSIDVTFFPFDQQNCTMKFGSWTYDKAKIDLVNMHSRVDQLDFWESGEW 209
>Y16282-1|CAA76155.1| 494|Homo sapiens nicotinic acetylcholine
receptor alpha6 subunit precursor protein.
Length = 494
Score = 62.9 bits (146), Expect = 2e-09
Identities = 44/184 (23%), Positives = 83/184 (45%), Gaps = 13/184 (7%)
Frame = +3
Query: 114 CENATSLSLMIDSLLATYDRDSPPDSKIVVNLTLHL-----RHANIRESESTVRIQADLQ 278
C + + L + Y++ P + +T+H + AN+ E + L+
Sbjct: 28 CVGCATEERLFHKLFSHYNQFIRPVENVSDPVTVHFEVAITQLANVDEVNQIMETNLWLR 87
Query: 279 MNWIDKRLSWNAGGV-GCSTWLVSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNG 443
W D +L W+ G T V ++++W+PD+VL N A GD+ + +A + NG
Sbjct: 88 HIWNDYKLRWDPMEYDGIETLRVPADKIWKPDIVLYNNAV---GDFQVEGKTKALLKYNG 144
Query: 444 SVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHTSDEMD-FVIDKRI--YSMFESG 614
++W + M + +P D Q C+ KFGS + E+D +I ++ +E+
Sbjct: 145 MITWTPPAIFKSSCPMDITFFPFDHQNCSLKFGSWTYDKAEIDLLIIGSKVDMNDFWENS 204
Query: 615 PWDV 626
W++
Sbjct: 205 EWEI 208
>U62435-1|AAB40113.1| 494|Homo sapiens nicotinic acetylcholine
receptor alpha6 subunit precursor protein.
Length = 494
Score = 62.9 bits (146), Expect = 2e-09
Identities = 44/184 (23%), Positives = 83/184 (45%), Gaps = 13/184 (7%)
Frame = +3
Query: 114 CENATSLSLMIDSLLATYDRDSPPDSKIVVNLTLHL-----RHANIRESESTVRIQADLQ 278
C + + L + Y++ P + +T+H + AN+ E + L+
Sbjct: 28 CVGCATEERLFHKLFSHYNQFIRPVENVSDPVTVHFEVAITQLANVDEVNQIMETNLWLR 87
Query: 279 MNWIDKRLSWNAGGV-GCSTWLVSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNG 443
W D +L W+ G T V ++++W+PD+VL N A GD+ + +A + NG
Sbjct: 88 HIWNDYKLRWDPMEYDGIETLRVPADKIWKPDIVLYNNAV---GDFQVEGKTKALLKYNG 144
Query: 444 SVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHTSDEMD-FVIDKRI--YSMFESG 614
++W + M + +P D Q C+ KFGS + E+D +I ++ +E+
Sbjct: 145 MITWTPPAIFKSSCPMDITFFPFDHQNCSLKFGSWTYDKAEIDLLIIGSKVDMNDFWENS 204
Query: 615 PWDV 626
W++
Sbjct: 205 EWEI 208
>BC014456-1|AAH14456.1| 494|Homo sapiens cholinergic receptor,
nicotinic, alpha 6 protein.
Length = 494
Score = 62.9 bits (146), Expect = 2e-09
Identities = 44/184 (23%), Positives = 83/184 (45%), Gaps = 13/184 (7%)
Frame = +3
Query: 114 CENATSLSLMIDSLLATYDRDSPPDSKIVVNLTLHL-----RHANIRESESTVRIQADLQ 278
C + + L + Y++ P + +T+H + AN+ E + L+
Sbjct: 28 CVGCATEERLFHKLFSHYNQFIRPVENVSDPVTVHFEVAITQLANVDEVNQIMETNLWLR 87
Query: 279 MNWIDKRLSWNAGGV-GCSTWLVSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNG 443
W D +L W+ G T V ++++W+PD+VL N A GD+ + +A + NG
Sbjct: 88 HIWNDYKLRWDPMEYDGIETLRVPADKIWKPDIVLYNNAV---GDFQVEGKTKALLKYNG 144
Query: 444 SVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHTSDEMD-FVIDKRI--YSMFESG 614
++W + M + +P D Q C+ KFGS + E+D +I ++ +E+
Sbjct: 145 MITWTPPAIFKSSCPMDITFFPFDHQNCSLKFGSWTYDKAEIDLLIIGSKVDMNDFWENS 204
Query: 615 PWDV 626
W++
Sbjct: 205 EWEI 208
>AB079251-1|BAC06855.1| 494|Homo sapiens Nicotinic acetylcholine
receptor alpha 6 protein.
Length = 494
Score = 62.9 bits (146), Expect = 2e-09
Identities = 44/184 (23%), Positives = 83/184 (45%), Gaps = 13/184 (7%)
Frame = +3
Query: 114 CENATSLSLMIDSLLATYDRDSPPDSKIVVNLTLHL-----RHANIRESESTVRIQADLQ 278
C + + L + Y++ P + +T+H + AN+ E + L+
Sbjct: 28 CVGCATEERLFHKLFSHYNQFIRPVENVSDPVTVHFEVAITQLANVDEVNQIMETNLWLR 87
Query: 279 MNWIDKRLSWNAGGV-GCSTWLVSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNG 443
W D +L W+ G T V ++++W+PD+VL N A GD+ + +A + NG
Sbjct: 88 HIWNDYKLRWDPMEYDGIETLRVPADKIWKPDIVLYNNAV---GDFQVEGKTKALLKYNG 144
Query: 444 SVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHTSDEMD-FVIDKRI--YSMFESG 614
++W + M + +P D Q C+ KFGS + E+D +I ++ +E+
Sbjct: 145 MITWTPPAIFKSSCPMDITFFPFDHQNCSLKFGSWTYDKAEIDLLIIGSKVDMNDFWENS 204
Query: 615 PWDV 626
W++
Sbjct: 205 EWEI 208
>X14830-1|CAA32939.1| 501|Homo sapiens protein ( Human mRNA for
muscle acetylcholine receptor beta-subunit. ).
Length = 501
Score = 61.7 bits (143), Expect = 4e-09
Identities = 45/130 (34%), Positives = 67/130 (51%), Gaps = 4/130 (3%)
Frame = +3
Query: 192 KIVVNLTL-HLRHANIRESESTVRIQADLQMNWIDKRLSWN-AGGVGCSTWLVSSERLWR 365
++ V L L L N ++ E + ++ DL+ W D RLSW+ A G + +++E +W
Sbjct: 53 RVSVGLILAQLISLNEKDEEMSTKVYLDLE--WTDYRLSWDPAEHDGIDSLRITAESVWL 110
Query: 366 PDVVLLNAAATTAGDYAL--RARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKF 539
PDVVLLN D AL VS++GSV W + S+Q+ +P D Q CT F
Sbjct: 111 PDVVLLNNNDGNF-DVALDISVVVSSDGSVRWQPPGIYRSSCSIQVTYFPFDWQNCTMVF 169
Query: 540 GSRMHTSDEM 569
S + S E+
Sbjct: 170 SSYSYDSSEV 179
>BC011371-1|AAH11371.1| 501|Homo sapiens cholinergic receptor,
nicotinic, beta 1 (muscle) protein.
Length = 501
Score = 61.7 bits (143), Expect = 4e-09
Identities = 45/130 (34%), Positives = 67/130 (51%), Gaps = 4/130 (3%)
Frame = +3
Query: 192 KIVVNLTL-HLRHANIRESESTVRIQADLQMNWIDKRLSWN-AGGVGCSTWLVSSERLWR 365
++ V L L L N ++ E + ++ DL+ W D RLSW+ A G + +++E +W
Sbjct: 53 RVSVGLILAQLISLNEKDEEMSTKVYLDLE--WTDYRLSWDPAEHDGIDSLRITAESVWL 110
Query: 366 PDVVLLNAAATTAGDYAL--RARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKF 539
PDVVLLN D AL VS++GSV W + S+Q+ +P D Q CT F
Sbjct: 111 PDVVLLNNNDGNF-DVALDISVVVSSDGSVRWQPPGIYRSSCSIQVTYFPFDWQNCTMVF 169
Query: 540 GSRMHTSDEM 569
S + S E+
Sbjct: 170 SSYSYDSSEV 179
>BC131799-1|AAI31800.1| 447|Homo sapiens 5-hydroxytryptamine
(serotonin) receptor 3, family member C protein.
Length = 447
Score = 61.3 bits (142), Expect = 5e-09
Identities = 29/114 (25%), Positives = 60/114 (52%), Gaps = 1/114 (0%)
Frame = +3
Query: 273 LQMNWIDKRLSWNAGG-VGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 449
+ + W + ++WN VG + V +E LW PD+ ++ + L A +S+ G +
Sbjct: 91 MDLVWDNPFINWNPKECVGINKLTVLAENLWLPDIFIVESMDVDQTPSGLTAYISSEGRI 150
Query: 450 SWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHTSDEMDFVIDKRIYSMFES 611
+ K + +++ ++ + +P D Q CTF F S ++T D M +DK ++ + ++
Sbjct: 151 KYDKPMRVTSICNLDIFYFPFDQQNCTFTFSSFLYTVDSMLLGMDKEVWEITDT 204
>DQ644022-1|ABG35128.1| 456|Homo sapiens 5-HT3 receptor subunit E
splice variant HTR3Ea protein.
Length = 456
Score = 60.9 bits (141), Expect = 6e-09
Identities = 34/133 (25%), Positives = 65/133 (48%), Gaps = 9/133 (6%)
Frame = +3
Query: 273 LQMNWIDKRLSWNAGGV-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 449
L+M W + +SWN G + ++++ LW PD+ ++ L A VSN G +
Sbjct: 91 LEMVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEGRI 150
Query: 450 SWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHTSDEMDFVIDKRIYSMFES------ 611
+ K + + + ++ + +P D Q CT F S ++T D M ++K ++ + ++
Sbjct: 151 RYKKPMKVDSICNLDIFYFPFDQQNCTLTFSSFLYTVDSMLLDMEKEVWEITDASRNILQ 210
Query: 612 --GPWDVTALSXA 644
G W++ LS A
Sbjct: 211 THGEWELLGLSKA 223
>BC101185-1|AAI01186.1| 374|Homo sapiens HTR3E protein protein.
Length = 374
Score = 60.9 bits (141), Expect = 6e-09
Identities = 34/133 (25%), Positives = 65/133 (48%), Gaps = 9/133 (6%)
Frame = +3
Query: 273 LQMNWIDKRLSWNAGGV-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 449
L+M W + +SWN G + ++++ LW PD+ ++ L A VSN G +
Sbjct: 20 LEMVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEGRI 79
Query: 450 SWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHTSDEMDFVIDKRIYSMFES------ 611
+ K + + + ++ + +P D Q CT F S ++T D M ++K ++ + ++
Sbjct: 80 RYKKPMKVDSICNLDIFYFPFDQQNCTLTFSSFLYTVDSMLLDMEKEVWEITDASRNILQ 139
Query: 612 --GPWDVTALSXA 644
G W++ LS A
Sbjct: 140 THGEWELLGLSKA 152
>BC101183-1|AAI01184.1| 471|Homo sapiens 5-hydroxytryptamine
(serotonin) receptor 3, family member E protein.
Length = 471
Score = 60.9 bits (141), Expect = 6e-09
Identities = 34/133 (25%), Positives = 65/133 (48%), Gaps = 9/133 (6%)
Frame = +3
Query: 273 LQMNWIDKRLSWNAGGV-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 449
L+M W + +SWN G + ++++ LW PD+ ++ L A VSN G +
Sbjct: 106 LEMVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEGRI 165
Query: 450 SWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHTSDEMDFVIDKRIYSMFES------ 611
+ K + + + ++ + +P D Q CT F S ++T D M ++K ++ + ++
Sbjct: 166 RYKKPMKVDSICNLDIFYFPFDQQNCTLTFSSFLYTVDSMLLDMEKEVWEITDASRNILQ 225
Query: 612 --GPWDVTALSXA 644
G W++ LS A
Sbjct: 226 THGEWELLGLSKA 238
>BC101182-1|AAI01183.1| 471|Homo sapiens 5-hydroxytryptamine
(serotonin) receptor 3, family member E protein.
Length = 471
Score = 60.9 bits (141), Expect = 6e-09
Identities = 34/133 (25%), Positives = 65/133 (48%), Gaps = 9/133 (6%)
Frame = +3
Query: 273 LQMNWIDKRLSWNAGGV-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 449
L+M W + +SWN G + ++++ LW PD+ ++ L A VSN G +
Sbjct: 106 LEMVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEGRI 165
Query: 450 SWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHTSDEMDFVIDKRIYSMFES------ 611
+ K + + + ++ + +P D Q CT F S ++T D M ++K ++ + ++
Sbjct: 166 RYKKPMKVDSICNLDIFYFPFDQQNCTLTFSSFLYTVDSMLLDMEKEVWEITDASRNILQ 225
Query: 612 --GPWDVTALSXA 644
G W++ LS A
Sbjct: 226 THGEWELLGLSKA 238
>AY159813-1|AAO38167.2| 471|Homo sapiens 5-hydroxytryptamine
serotonin receptor 3E protein.
Length = 471
Score = 60.9 bits (141), Expect = 6e-09
Identities = 34/133 (25%), Positives = 65/133 (48%), Gaps = 9/133 (6%)
Frame = +3
Query: 273 LQMNWIDKRLSWNAGGV-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 449
L+M W + +SWN G + ++++ LW PD+ ++ L A VSN G +
Sbjct: 106 LEMVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEGRI 165
Query: 450 SWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHTSDEMDFVIDKRIYSMFES------ 611
+ K + + + ++ + +P D Q CT F S ++T D M ++K ++ + ++
Sbjct: 166 RYKKPMKVDSICNLDIFYFPFDQQNCTLTFSSFLYTVDSMLLDMEKEVWEITDASRNILQ 225
Query: 612 --GPWDVTALSXA 644
G W++ LS A
Sbjct: 226 THGEWELLGLSKA 238
>AF459285-1|AAL66182.1| 447|Homo sapiens 5-hydroxytryptamine
receptor 3 subunit C protein.
Length = 447
Score = 60.9 bits (141), Expect = 6e-09
Identities = 29/114 (25%), Positives = 59/114 (51%), Gaps = 1/114 (0%)
Frame = +3
Query: 273 LQMNWIDKRLSWNAGG-VGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 449
+ + W + ++WN VG + V +E LW PD+ ++ + L A +S+ G +
Sbjct: 91 MDLVWDNPFINWNPKECVGINKLTVLAENLWLPDIFIVESMDVDQTPSGLTAYISSEGRI 150
Query: 450 SWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHTSDEMDFVIDKRIYSMFES 611
+ K + +++ + + +P D Q CTF F S ++T D M +DK ++ + ++
Sbjct: 151 KYDKPMRVTSICKLDIFYFPFDQQNCTFTFSSFLYTVDSMLLGMDKEVWEITDT 204
>BC023553-1|AAH23553.1| 501|Homo sapiens cholinergic receptor,
nicotinic, beta 1 (muscle) protein.
Length = 501
Score = 60.5 bits (140), Expect = 8e-09
Identities = 43/132 (32%), Positives = 68/132 (51%), Gaps = 6/132 (4%)
Frame = +3
Query: 192 KIVVNLTL-HLRHANIRESESTVRIQADLQMNWIDKRLSWN-AGGVGCSTWLVSSERLWR 365
++ V L L L N ++ E + ++ DL+ W D RLSW+ A G + +++E +W
Sbjct: 53 RVSVGLILAQLISLNEKDEEMSTKVYLDLE--WTDYRLSWDPAEHDGIDSLRITAESVWL 110
Query: 366 PDVVLLNAAATTAGDY----ALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTF 533
PDVVLLN G++ + VS++GSV W + S+Q+ +P D Q CT
Sbjct: 111 PDVVLLN---NNDGNFYVALDISVVVSSDGSVRWQPPGIYRSSCSIQVTYFPFDWQNCTM 167
Query: 534 KFGSRMHTSDEM 569
F S + S E+
Sbjct: 168 VFSSYSYDSSEV 179
>X01715-1|CAA25861.1| 520|Homo sapiens acetylcholine receptor gamma
chain precursor protein.
Length = 520
Score = 60.1 bits (139), Expect = 1e-08
Identities = 43/157 (27%), Positives = 74/157 (47%), Gaps = 8/157 (5%)
Frame = +3
Query: 141 MIDSLLATYDRDSPPDSKI--VVNLTLHLRHANI---RESESTVRIQADLQMNWIDKRLS 305
++ L+ YD + P + VVN++L L N+ E E + ++M W D RL
Sbjct: 32 LLADLMQNYDPNLRPAERDSDVVNVSLKLTLTNLISLNEREEALTTNVWIEMQWCDYRLR 91
Query: 306 WNAGGV-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARV--SNNGSVSWIKRLDIS 476
W+ G V S +WRPD+VL N + AL V S +G + W+
Sbjct: 92 WDPRDYEGLWVLRVPSTMVWRPDIVLENNVDGVF-EVALYCNVLVSPDGCIYWLPPAIFR 150
Query: 477 TPISMQLDNWPNDMQTCTFKFGSRMHTSDEMDFVIDK 587
+ S+ + +P D Q C+ F S+ ++++E+D + +
Sbjct: 151 SACSISVTYFPFDWQNCSLIFQSQTYSTNEIDLQLSQ 187
>AC092165-3|AAY24103.1| 520|Homo sapiens unknown protein.
Length = 520
Score = 60.1 bits (139), Expect = 1e-08
Identities = 43/157 (27%), Positives = 74/157 (47%), Gaps = 8/157 (5%)
Frame = +3
Query: 141 MIDSLLATYDRDSPPDSKI--VVNLTLHLRHANI---RESESTVRIQADLQMNWIDKRLS 305
++ L+ YD + P + VVN++L L N+ E E + ++M W D RL
Sbjct: 32 LLADLMQNYDPNLRPAERDSDVVNVSLKLTLTNLISLNEREEALTTNVWIEMQWCDYRLR 91
Query: 306 WNAGGV-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARV--SNNGSVSWIKRLDIS 476
W+ G V S +WRPD+VL N + AL V S +G + W+
Sbjct: 92 WDPRDYEGLWVLRVPSTMVWRPDIVLENNVDGVF-EVALYCNVLVSPDGCIYWLPPAIFR 150
Query: 477 TPISMQLDNWPNDMQTCTFKFGSRMHTSDEMDFVIDK 587
+ S+ + +P D Q C+ F S+ ++++E+D + +
Sbjct: 151 SACSISVTYFPFDWQNCSLIFQSQTYSTNEIDLQLSQ 187
>X66403-1|CAA47030.1| 493|Homo sapiens acetylcholine receptor
epsilon subunit CHRNE protein.
Length = 493
Score = 59.7 bits (138), Expect = 1e-08
Identities = 35/134 (26%), Positives = 68/134 (50%), Gaps = 3/134 (2%)
Frame = +3
Query: 183 PDSKIVVNLTLHLRHA-NIRESESTVRIQADLQMNWIDKRLSWNAGGVG-CSTWLVSSER 356
P+ + ++L + L + ++ E E T+ + ++W D RL+++ G T V SE
Sbjct: 45 PEDTVTISLKVTLTNLISLNEKEETLTTSVWIGIDWQDYRLNYSKDDFGGIETLRVPSEL 104
Query: 357 LWRPDVVLLNAAATTAG-DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTF 533
+W P++VL N G Y V GSV+W+ + ++++ +P D Q C+
Sbjct: 105 VWLPEIVLENNIDGQFGVAYDANVLVYEGGSVTWLPPAIYRSVCAVEVTYFPFDWQNCSL 164
Query: 534 KFGSRMHTSDEMDF 575
F S+ + ++E++F
Sbjct: 165 IFRSQTYNAEEVEF 178
>AF105999-1|AAD24503.1| 493|Homo sapiens acetylcholine receptor
epsilon subunit protein.
Length = 493
Score = 59.7 bits (138), Expect = 1e-08
Identities = 35/134 (26%), Positives = 68/134 (50%), Gaps = 3/134 (2%)
Frame = +3
Query: 183 PDSKIVVNLTLHLRHA-NIRESESTVRIQADLQMNWIDKRLSWNAGGVG-CSTWLVSSER 356
P+ + ++L + L + ++ E E T+ + ++W D RL+++ G T V SE
Sbjct: 45 PEDTVTISLKVTLTNLISLNEKEETLTTSVWIGIDWQDYRLNYSKDDFGGIETLRVPSEL 104
Query: 357 LWRPDVVLLNAAATTAG-DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTF 533
+W P++VL N G Y V GSV+W+ + ++++ +P D Q C+
Sbjct: 105 VWLPEIVLENNIDGQFGVAYDANVLVYEGGSVTWLPPAIYRSVCAVEVTYFPFDWQNCSL 164
Query: 534 KFGSRMHTSDEMDF 575
F S+ + ++E++F
Sbjct: 165 IFRSQTYNAEEVEF 178
>AY349353-1|AAQ93477.1| 456|Homo sapiens 5-HT3c1 serotonin
receptor-like protein protein.
Length = 456
Score = 59.3 bits (137), Expect = 2e-08
Identities = 34/137 (24%), Positives = 66/137 (48%), Gaps = 9/137 (6%)
Frame = +3
Query: 261 IQADLQMNWIDKRLSWNAGGV-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSN 437
+ A L + W + +SWN G + ++++ LW PD+ ++ L A VSN
Sbjct: 87 MSAILDVVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSN 146
Query: 438 NGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHTSDEMDFVIDKRIYSMFES-- 611
G + + K + + + ++ + +P D Q CT F S ++T D M ++K ++ + ++
Sbjct: 147 EGRIRYKKPMKVDSICNLDIFYFPFDQQNCTLTFSSFLYTVDSMLLDMEKEVWEITDASR 206
Query: 612 ------GPWDVTALSXA 644
G W++ LS A
Sbjct: 207 NILQTHGEWELLGLSKA 223
>AY349352-1|AAQ93476.1| 441|Homo sapiens 5-HT3c1 serotonin
receptor-like protein protein.
Length = 441
Score = 59.3 bits (137), Expect = 2e-08
Identities = 34/137 (24%), Positives = 66/137 (48%), Gaps = 9/137 (6%)
Frame = +3
Query: 261 IQADLQMNWIDKRLSWNAGGV-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSN 437
+ A L + W + +SWN G + ++++ LW PD+ ++ L A VSN
Sbjct: 72 MSAILDVVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSN 131
Query: 438 NGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHTSDEMDFVIDKRIYSMFES-- 611
G + + K + + + ++ + +P D Q CT F S ++T D M ++K ++ + ++
Sbjct: 132 EGRIRYKKPMKVDSICNLDIFYFPFDQQNCTLTFSSFLYTVDSMLLDMEKEVWEITDASR 191
Query: 612 ------GPWDVTALSXA 644
G W++ LS A
Sbjct: 192 NILQTHGEWELLGLSKA 208
>Y00762-1|CAA68731.1| 457|Homo sapiens protein ( Human mRNA for
muscle acetylcholine receptor alpha-subunit. ).
Length = 457
Score = 56.4 bits (130), Expect = 1e-07
Identities = 34/123 (27%), Positives = 59/123 (47%), Gaps = 5/123 (4%)
Frame = +3
Query: 192 KIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWNAGGVGCSTWL-VSSERLWRP 368
++ V L L ++ N+ E V L+ W+D L WN G + + SE++WRP
Sbjct: 50 EVTVGLQL-IQLINVDEVNQIVTTNVRLKQQWVDYNLKWNPDDYGGVKKIHIPSEKIWRP 108
Query: 369 DVVLLNAAATTAGDYAL----RARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFK 536
D+VL N A GD+A+ + + G ++W + + + ++P D Q C+ K
Sbjct: 109 DLVLYNNA---DGDFAIVKFTKVLLQYTGHITWTPPAIFKSYCEIIVTHFPFDEQNCSMK 165
Query: 537 FGS 545
G+
Sbjct: 166 LGT 168
>X02502-1|CAA26344.1| 457|Homo sapiens acetylcholine receptor
protein.
Length = 457
Score = 56.4 bits (130), Expect = 1e-07
Identities = 34/123 (27%), Positives = 59/123 (47%), Gaps = 5/123 (4%)
Frame = +3
Query: 192 KIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWNAGGVGCSTWL-VSSERLWRP 368
++ V L L ++ N+ E V L+ W+D L WN G + + SE++WRP
Sbjct: 50 EVTVGLQL-IQLINVDEVNQIVTTNVRLKQQWVDYNLKWNPDDYGGVKKIHIPSEKIWRP 108
Query: 369 DVVLLNAAATTAGDYAL----RARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFK 536
D+VL N A GD+A+ + + G ++W + + + ++P D Q C+ K
Sbjct: 109 DLVLYNNA---DGDFAIVKFTKVLLQYTGHITWTPPAIFKSYCEIIVTHFPFDEQNCSMK 165
Query: 537 FGS 545
G+
Sbjct: 166 LGT 168
>S77094-1|AAD14247.1| 457|Homo sapiens nicotinic acetylcholine
receptor alpha subunit|AChR protein.
Length = 457
Score = 56.4 bits (130), Expect = 1e-07
Identities = 34/123 (27%), Positives = 59/123 (47%), Gaps = 5/123 (4%)
Frame = +3
Query: 192 KIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWNAGGVGCSTWL-VSSERLWRP 368
++ V L L ++ N+ E V L+ W+D L WN G + + SE++WRP
Sbjct: 50 EVTVGLQL-IQLINVDEVNQIVTTNVRLKQQWVDYNLKWNPDDYGGVKKIHIPSEKIWRP 108
Query: 369 DVVLLNAAATTAGDYAL----RARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFK 536
D+VL N A GD+A+ + + G ++W + + + ++P D Q C+ K
Sbjct: 109 DLVLYNNA---DGDFAIVKFTKVLLQYTGHITWTPPAIFKSYCEIIVTHFPFDEQNCSMK 165
Query: 537 FGS 545
G+
Sbjct: 166 LGT 168
>BC110597-1|AAI10598.1| 411|Homo sapiens ligand-gated ion channel,
zinc activated 1 protein.
Length = 411
Score = 56.4 bits (130), Expect = 1e-07
Identities = 29/101 (28%), Positives = 50/101 (49%)
Frame = +3
Query: 273 LQMNWIDKRLSWNAGGVGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVS 452
L+++W+D RL+WN + E LW P + +L A D + +ARV +G V
Sbjct: 86 LRLSWLDTRLAWNTSAHPRHAITLPWESLWTPRLTILEALWVDWRDQSPQARVDQDGHVK 145
Query: 453 WIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHTSDEMDF 575
L T + +L ++P D C+ F + +T+ E++F
Sbjct: 146 LNLALTTETNCNFELLHFPRDHSNCSLSFYALSNTAMELEF 186
>BC006314-1|AAH06314.1| 269|Homo sapiens CHRNA1 protein protein.
Length = 269
Score = 56.4 bits (130), Expect = 1e-07
Identities = 34/123 (27%), Positives = 59/123 (47%), Gaps = 5/123 (4%)
Frame = +3
Query: 192 KIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWNAGGVGCSTWL-VSSERLWRP 368
++ V L L ++ N+ E V L+ W+D L WN G + + SE++WRP
Sbjct: 50 EVTVGLQL-IQLINVDEVNQIVTTNVRLKQQWVDYNLKWNPDDYGGVKKIHIPSEKIWRP 108
Query: 369 DVVLLNAAATTAGDYAL----RARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFK 536
D+VL N A GD+A+ + + G ++W + + + ++P D Q C+ K
Sbjct: 109 DLVLYNNA---DGDFAIVKFTKVLLQYTGHITWTPPAIFKSYCEIIVTHFPFDEQNCSMK 165
Query: 537 FGS 545
G+
Sbjct: 166 LGT 168
>AF512521-1|AAO20969.1| 411|Homo sapiens ligand-gated ion channel
subunit protein.
Length = 411
Score = 56.4 bits (130), Expect = 1e-07
Identities = 29/101 (28%), Positives = 50/101 (49%)
Frame = +3
Query: 273 LQMNWIDKRLSWNAGGVGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVS 452
L+++W+D RL+WN + E LW P + +L A D + +ARV +G V
Sbjct: 86 LRLSWLDTRLAWNTSAHPRHAITLPWESLWTPRLTILEALWVDWRDQSPQARVDQDGHVK 145
Query: 453 WIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHTSDEMDF 575
L T + +L ++P D C+ F + +T+ E++F
Sbjct: 146 LNLALTTETNCNFELLHFPRDHSNCSLSFYALSNTAMELEF 186
>AC018890-1|AAY14687.1| 457|Homo sapiens unknown protein.
Length = 457
Score = 56.4 bits (130), Expect = 1e-07
Identities = 34/123 (27%), Positives = 59/123 (47%), Gaps = 5/123 (4%)
Frame = +3
Query: 192 KIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWNAGGVGCSTWL-VSSERLWRP 368
++ V L L ++ N+ E V L+ W+D L WN G + + SE++WRP
Sbjct: 50 EVTVGLQL-IQLINVDEVNQIVTTNVRLKQQWVDYNLKWNPDDYGGVKKIHIPSEKIWRP 108
Query: 369 DVVLLNAAATTAGDYAL----RARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFK 536
D+VL N A GD+A+ + + G ++W + + + ++P D Q C+ K
Sbjct: 109 DLVLYNNA---DGDFAIVKFTKVLLQYTGHITWTPPAIFKSYCEIIVTHFPFDEQNCSMK 165
Query: 537 FGS 545
G+
Sbjct: 166 LGT 168
>AJ295237-1|CAC16144.1| 450|Homo sapiens neuronal nicotinic
acetylcholine receptor subunit4 protein.
Length = 450
Score = 56.0 bits (129), Expect = 2e-07
Identities = 48/166 (28%), Positives = 72/166 (43%), Gaps = 11/166 (6%)
Frame = +3
Query: 108 AEC---ENATSLSLMIDSLLATYDRDSPP--DSKIVVNLTLHLRHANI---RESESTVRI 263
AEC E +L L D L A Y P D+ +N+TL + + I E + +
Sbjct: 20 AECLGAEGRLALKLFRD-LFANYTSALRPVADTDQTLNVTLEVTLSQIIDMDERNQVLTL 78
Query: 264 QADLQMNWIDKRLSW--NAGGVGCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVS 434
++ W D L W NA G G + S +WRPD+VL N A A G + +
Sbjct: 79 YLWIRQEWTDAYLRWDPNAYG-GLDAIRIPSSLVWRPDIVLYNKADAQPPGSASTNVVLR 137
Query: 435 NNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHTSDEMD 572
++G+V W + + + +P D Q C FGS H ++D
Sbjct: 138 HDGAVRWDAPAITRSSCRVDVAAFPFDAQHCGLTFGSWTHGGHQLD 183
>AJ278118-1|CAC20435.1| 450|Homo sapiens neuronal nicotinic
acetylcholine alpha10 subunit protein.
Length = 450
Score = 56.0 bits (129), Expect = 2e-07
Identities = 48/166 (28%), Positives = 72/166 (43%), Gaps = 11/166 (6%)
Frame = +3
Query: 108 AEC---ENATSLSLMIDSLLATYDRDSPP--DSKIVVNLTLHLRHANI---RESESTVRI 263
AEC E +L L D L A Y P D+ +N+TL + + I E + +
Sbjct: 20 AECLGAEGRLALKLFRD-LFANYTSALRPVADTDQTLNVTLEVTLSQIIDMDERNQVLTL 78
Query: 264 QADLQMNWIDKRLSW--NAGGVGCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVS 434
++ W D L W NA G G + S +WRPD+VL N A A G + +
Sbjct: 79 YLWIRQEWTDAYLRWDPNAYG-GLDAIRIPSSLVWRPDIVLYNKADAQPPGSASTNVVLR 137
Query: 435 NNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHTSDEMD 572
++G+V W + + + +P D Q C FGS H ++D
Sbjct: 138 HDGAVRWDAPAITRSSCRVDVAAFPFDAQHCGLTFGSWTHGGHQLD 183
>AF327367-1|AAK14333.1| 450|Homo sapiens nicotinic acetylcholine
receptor subunit alpha 10 protein.
Length = 450
Score = 56.0 bits (129), Expect = 2e-07
Identities = 48/166 (28%), Positives = 72/166 (43%), Gaps = 11/166 (6%)
Frame = +3
Query: 108 AEC---ENATSLSLMIDSLLATYDRDSPP--DSKIVVNLTLHLRHANI---RESESTVRI 263
AEC E +L L D L A Y P D+ +N+TL + + I E + +
Sbjct: 20 AECLGAEGRLALKLFRD-LFANYTSALRPVADTDQTLNVTLEVTLSQIIDMDERNQVLTL 78
Query: 264 QADLQMNWIDKRLSW--NAGGVGCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVS 434
++ W D L W NA G G + S +WRPD+VL N A A G + +
Sbjct: 79 YLWIRQEWTDAYLRWDPNAYG-GLDAIRIPSSLVWRPDIVLYNKADAQPPGSASTNVVLR 137
Query: 435 NNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHTSDEMD 572
++G+V W + + + +P D Q C FGS H ++D
Sbjct: 138 HDGAVRWDAPAITRSSCRVDVAAFPFDAQHCGLTFGSWTHGGHQLD 183
>AF199235-1|AAG00795.2| 450|Homo sapiens nicotinic acetylcholine
receptor subunit alpha 10 protein.
Length = 450
Score = 56.0 bits (129), Expect = 2e-07
Identities = 48/166 (28%), Positives = 72/166 (43%), Gaps = 11/166 (6%)
Frame = +3
Query: 108 AEC---ENATSLSLMIDSLLATYDRDSPP--DSKIVVNLTLHLRHANI---RESESTVRI 263
AEC E +L L D L A Y P D+ +N+TL + + I E + +
Sbjct: 20 AECLGAEGRLALKLFRD-LFANYTSALRPVADTDQTLNVTLEVTLSQIIDMDERNQVLTL 78
Query: 264 QADLQMNWIDKRLSW--NAGGVGCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVS 434
++ W D L W NA G G + S +WRPD+VL N A A G + +
Sbjct: 79 YLWIRQEWTDAYLRWDPNAYG-GLDAIRIPSSLVWRPDIVLYNKADAQPPGSASTNVVLR 137
Query: 435 NNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHTSDEMD 572
++G+V W + + + +P D Q C FGS H ++D
Sbjct: 138 HDGAVRWDAPAITRSSCRVDVAAFPFDAQHCGLTFGSWTHGGHQLD 183
>AB223030-1|BAE19924.1| 411|Homo sapiens ligand-gated ion-channel
receptor L2 protein.
Length = 411
Score = 56.0 bits (129), Expect = 2e-07
Identities = 29/101 (28%), Positives = 50/101 (49%)
Frame = +3
Query: 273 LQMNWIDKRLSWNAGGVGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVS 452
L+++W+D RL+WN + E LW P + +L A D + +ARV +G V
Sbjct: 86 LRLSWLDTRLAWNTSAHPRHAITLPWESLWTPRLTILEALWVDWRDQSPQARVDQDGHVK 145
Query: 453 WIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHTSDEMDF 575
L T + +L ++P D C+ F + +T+ E++F
Sbjct: 146 LNLALATETNCNFELLHFPRDHSNCSLSFYALSNTAMELEF 186
>X55019-1|CAA38759.1| 517|Homo sapiens acetylcholine receptor delta
subunit protein.
Length = 517
Score = 55.6 bits (128), Expect = 2e-07
Identities = 35/131 (26%), Positives = 61/131 (46%), Gaps = 3/131 (2%)
Frame = +3
Query: 186 DSKIVVNLTLHLRHA-NIRESESTVRIQADLQMNWIDKRLSWNAGGVG-CSTWLVSSERL 359
+ + V L L L + +++E E T+ ++ W D RL WNA G S + + +
Sbjct: 49 EESVDVALALTLSNLISLKEVEETLTTNVWIEHGWTDNRLKWNAEEFGNISVLRLPPDMV 108
Query: 360 WRPDVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFK 536
W P++VL N + Y+ V + G V W+ + + + +P D Q C+ K
Sbjct: 109 WLPEIVLENNNDGSFQISYSCNVLVYHYGFVYWLPPAIFRSSCPISVTYFPFDWQNCSLK 168
Query: 537 FGSRMHTSDEM 569
F S +T+ E+
Sbjct: 169 FSSLKYTAKEI 179
>BC093925-1|AAH93925.1| 517|Homo sapiens cholinergic receptor,
nicotinic, delta protein.
Length = 517
Score = 55.6 bits (128), Expect = 2e-07
Identities = 35/131 (26%), Positives = 61/131 (46%), Gaps = 3/131 (2%)
Frame = +3
Query: 186 DSKIVVNLTLHLRHA-NIRESESTVRIQADLQMNWIDKRLSWNAGGVG-CSTWLVSSERL 359
+ + V L L L + +++E E T+ ++ W D RL WNA G S + + +
Sbjct: 49 EESVDVALALTLSNLISLKEVEETLTTNVWIEHGWTDNRLKWNAEEFGNISVLRLPPDMV 108
Query: 360 WRPDVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFK 536
W P++VL N + Y+ V + G V W+ + + + +P D Q C+ K
Sbjct: 109 WLPEIVLENNNDGSFQISYSCNVLVYHYGFVYWLPPAIFRSSCPISVTYFPFDWQNCSLK 168
Query: 537 FGSRMHTSDEM 569
F S +T+ E+
Sbjct: 169 FSSLKYTAKEI 179
>BC093923-1|AAH93923.1| 517|Homo sapiens cholinergic receptor,
nicotinic, delta protein.
Length = 517
Score = 55.6 bits (128), Expect = 2e-07
Identities = 35/131 (26%), Positives = 61/131 (46%), Gaps = 3/131 (2%)
Frame = +3
Query: 186 DSKIVVNLTLHLRHA-NIRESESTVRIQADLQMNWIDKRLSWNAGGVG-CSTWLVSSERL 359
+ + V L L L + +++E E T+ ++ W D RL WNA G S + + +
Sbjct: 49 EESVDVALALTLSNLISLKEVEETLTTNVWIEHGWTDNRLKWNAEEFGNISVLRLPPDMV 108
Query: 360 WRPDVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFK 536
W P++VL N + Y+ V + G V W+ + + + +P D Q C+ K
Sbjct: 109 WLPEIVLENNNDGSFQISYSCNVLVYHYGFVYWLPPAIFRSSCPISVTYFPFDWQNCSLK 168
Query: 537 FGSRMHTSDEM 569
F S +T+ E+
Sbjct: 169 FSSLKYTAKEI 179
>AC092165-2|AAY24102.1| 517|Homo sapiens unknown protein.
Length = 517
Score = 55.6 bits (128), Expect = 2e-07
Identities = 35/131 (26%), Positives = 61/131 (46%), Gaps = 3/131 (2%)
Frame = +3
Query: 186 DSKIVVNLTLHLRHA-NIRESESTVRIQADLQMNWIDKRLSWNAGGVG-CSTWLVSSERL 359
+ + V L L L + +++E E T+ ++ W D RL WNA G S + + +
Sbjct: 49 EESVDVALALTLSNLISLKEVEETLTTNVWIEHGWTDNRLKWNAEEFGNISVLRLPPDMV 108
Query: 360 WRPDVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFK 536
W P++VL N + Y+ V + G V W+ + + + +P D Q C+ K
Sbjct: 109 WLPEIVLENNNDGSFQISYSCNVLVYHYGFVYWLPPAIFRSSCPISVTYFPFDWQNCSLK 168
Query: 537 FGSRMHTSDEM 569
F S +T+ E+
Sbjct: 169 FSSLKYTAKEI 179
>M59216-1|AAA35862.1| 474|Homo sapiens gamma-aminobutyric acid
receptor beta-1 subunit protein.
Length = 474
Score = 54.8 bits (126), Expect = 4e-07
Identities = 41/169 (24%), Positives = 75/169 (44%), Gaps = 7/169 (4%)
Frame = +3
Query: 90 CAIASAAECENATSLSLMIDSLLATYDRDSPPD---SKIVVNLTLHLRHAN-IRESESTV 257
C S E N + + +D LL YD PD + V + + + + + E
Sbjct: 23 CCAHSTNEPSNMSYVKETVDRLLKGYDIRLRPDFGGPPVDVGMRIDVASIDMVSEVNMDY 82
Query: 258 RIQADLQMNWIDKRLSWNAGGVGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSN 437
+ Q +W DKRLS++ + + +++LW PD LN + ++ R+
Sbjct: 83 TLTMYFQQSWKDKRLSYSGIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIR 142
Query: 438 ---NGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHTSDEMDF 575
+G+V + R+ + M L +P D Q CT + S +T+D+++F
Sbjct: 143 LHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEF 191
>L08485-1|AAA58490.1| 462|Homo sapiens GABA-benzodiazepine receptor
alpha-5-subunit protein.
Length = 462
Score = 54.8 bits (126), Expect = 4e-07
Identities = 39/161 (24%), Positives = 73/161 (45%), Gaps = 7/161 (4%)
Frame = +3
Query: 117 ENATSLSLMIDSLLATYDRDSPPD--SKIV-VNLTLHLRHAN-IRESESTVRIQADLQMN 284
+N T + ++D LL YD P +I V +++ + ++E I + +
Sbjct: 44 DNITIFTRILDGLLDGYDNRLRPGLGERITQVRTDIYVTSFGPVSDTEMEYTIDVFFRQS 103
Query: 285 WIDKRLSWNAGGVGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSW 455
W D+RL + + + ++W PD N + A + R+ ++G++ +
Sbjct: 104 WKDERLRFKGPMQRLPLNNLLASKIWTPDTFFHNGKKSIAHNMTTPNKLLRLEDDGTLLY 163
Query: 456 IKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHTSDEMDFV 578
RL IS MQL+++P D C KFGS + + E+ +V
Sbjct: 164 TMRLTISAECPMQLEDFPMDAHACPLKFGSYAYPNSEVVYV 204
>BT009830-1|AAP88832.1| 462|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 5 protein.
Length = 462
Score = 54.8 bits (126), Expect = 4e-07
Identities = 39/161 (24%), Positives = 73/161 (45%), Gaps = 7/161 (4%)
Frame = +3
Query: 117 ENATSLSLMIDSLLATYDRDSPPD--SKIV-VNLTLHLRHAN-IRESESTVRIQADLQMN 284
+N T + ++D LL YD P +I V +++ + ++E I + +
Sbjct: 44 DNITIFTRILDGLLDGYDNRLRPGLGERITQVRTDIYVTSFGPVSDTEMEYTIDVFFRQS 103
Query: 285 WIDKRLSWNAGGVGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSW 455
W D+RL + + + ++W PD N + A + R+ ++G++ +
Sbjct: 104 WKDERLRFKGPMQRLPLNNLLASKIWTPDTFFHNGKKSIAHNMTTPNKLLRLEDDGTLLY 163
Query: 456 IKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHTSDEMDFV 578
RL IS MQL+++P D C KFGS + + E+ +V
Sbjct: 164 TMRLTISAECPMQLEDFPMDAHACPLKFGSYAYPNSEVVYV 204
>BC113422-1|AAI13423.1| 462|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 5 protein.
Length = 462
Score = 54.8 bits (126), Expect = 4e-07
Identities = 39/161 (24%), Positives = 73/161 (45%), Gaps = 7/161 (4%)
Frame = +3
Query: 117 ENATSLSLMIDSLLATYDRDSPPD--SKIV-VNLTLHLRHAN-IRESESTVRIQADLQMN 284
+N T + ++D LL YD P +I V +++ + ++E I + +
Sbjct: 44 DNITIFTRILDGLLDGYDNRLRPGLGERITQVRTDIYVTSFGPVSDTEMEYTIDVFFRQS 103
Query: 285 WIDKRLSWNAGGVGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSW 455
W D+RL + + + ++W PD N + A + R+ ++G++ +
Sbjct: 104 WKDERLRFKGPMQRLPLNNLLASKIWTPDTFFHNGKKSIAHNMTTPNKLLRLEDDGTLLY 163
Query: 456 IKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHTSDEMDFV 578
RL IS MQL+++P D C KFGS + + E+ +V
Sbjct: 164 TMRLTISAECPMQLEDFPMDAHACPLKFGSYAYPNSEVVYV 204
>BC111979-1|AAI11980.1| 462|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 5, precursor protein.
Length = 462
Score = 54.8 bits (126), Expect = 4e-07
Identities = 39/161 (24%), Positives = 73/161 (45%), Gaps = 7/161 (4%)
Frame = +3
Query: 117 ENATSLSLMIDSLLATYDRDSPPD--SKIV-VNLTLHLRHAN-IRESESTVRIQADLQMN 284
+N T + ++D LL YD P +I V +++ + ++E I + +
Sbjct: 44 DNITIFTRILDGLLDGYDNRLRPGLGERITQVRTDIYVTSFGPVSDTEMEYTIDVFFRQS 103
Query: 285 WIDKRLSWNAGGVGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSW 455
W D+RL + + + ++W PD N + A + R+ ++G++ +
Sbjct: 104 WKDERLRFKGPMQRLPLNNLLASKIWTPDTFFHNGKKSIAHNMTTPNKLLRLEDDGTLLY 163
Query: 456 IKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHTSDEMDFV 578
RL IS MQL+++P D C KFGS + + E+ +V
Sbjct: 164 TMRLTISAECPMQLEDFPMDAHACPLKFGSYAYPNSEVVYV 204
>S77554-1|AAB33983.1| 474|Homo sapiens GABAA receptor beta 2
subunit protein.
Length = 474
Score = 54.4 bits (125), Expect = 6e-07
Identities = 42/169 (24%), Positives = 75/169 (44%), Gaps = 7/169 (4%)
Frame = +3
Query: 90 CAIASAAECENATSLSLMIDSLLATYDRDSPPD---SKIVVNLTLHLRHAN-IRESESTV 257
CA S + N + + +D LL YD PD + V + + + + + E
Sbjct: 23 CA-QSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDIASIDMVSEVNMDY 81
Query: 258 RIQADLQMNWIDKRLSWNAGGVGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSN 437
+ Q W DKRLS+N + + +++LW PD LN + ++ R+
Sbjct: 82 TLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIR 141
Query: 438 ---NGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHTSDEMDF 575
+G+V + R+ + M L +P D Q CT + S +T+D+++F
Sbjct: 142 LHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEF 190
>S77553-1|AAB33982.1| 512|Homo sapiens GABAA receptor beta 2
subunit protein.
Length = 512
Score = 54.4 bits (125), Expect = 6e-07
Identities = 42/169 (24%), Positives = 75/169 (44%), Gaps = 7/169 (4%)
Frame = +3
Query: 90 CAIASAAECENATSLSLMIDSLLATYDRDSPPD---SKIVVNLTLHLRHAN-IRESESTV 257
CA S + N + + +D LL YD PD + V + + + + + E
Sbjct: 23 CA-QSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDIASIDMVSEVNMDY 81
Query: 258 RIQADLQMNWIDKRLSWNAGGVGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSN 437
+ Q W DKRLS+N + + +++LW PD LN + ++ R+
Sbjct: 82 TLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIR 141
Query: 438 ---NGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHTSDEMDF 575
+G+V + R+ + M L +P D Q CT + S +T+D+++F
Sbjct: 142 LHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEF 190
>S67368-1|AAB29370.1| 474|Homo sapiens gamma-aminobutyric acid A
receptor beta 2 subunit protein.
Length = 474
Score = 54.4 bits (125), Expect = 6e-07
Identities = 42/169 (24%), Positives = 75/169 (44%), Gaps = 7/169 (4%)
Frame = +3
Query: 90 CAIASAAECENATSLSLMIDSLLATYDRDSPPD---SKIVVNLTLHLRHAN-IRESESTV 257
CA S + N + + +D LL YD PD + V + + + + + E
Sbjct: 23 CA-QSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDIASIDMVSEVNMDY 81
Query: 258 RIQADLQMNWIDKRLSWNAGGVGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSN 437
+ Q W DKRLS+N + + +++LW PD LN + ++ R+
Sbjct: 82 TLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIR 141
Query: 438 ---NGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHTSDEMDF 575
+G+V + R+ + M L +P D Q CT + S +T+D+++F
Sbjct: 142 LHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEF 190
>BC105639-1|AAI05640.1| 474|Homo sapiens GABRB2 protein protein.
Length = 474
Score = 54.4 bits (125), Expect = 6e-07
Identities = 42/169 (24%), Positives = 75/169 (44%), Gaps = 7/169 (4%)
Frame = +3
Query: 90 CAIASAAECENATSLSLMIDSLLATYDRDSPPD---SKIVVNLTLHLRHAN-IRESESTV 257
CA S + N + + +D LL YD PD + V + + + + + E
Sbjct: 23 CA-QSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDIASIDMVSEVNMDY 81
Query: 258 RIQADLQMNWIDKRLSWNAGGVGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSN 437
+ Q W DKRLS+N + + +++LW PD LN + ++ R+
Sbjct: 82 TLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIR 141
Query: 438 ---NGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHTSDEMDF 575
+G+V + R+ + M L +P D Q CT + S +T+D+++F
Sbjct: 142 LHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEF 190
>BC099719-1|AAH99719.1| 474|Homo sapiens GABRB2 protein protein.
Length = 474
Score = 54.4 bits (125), Expect = 6e-07
Identities = 42/169 (24%), Positives = 75/169 (44%), Gaps = 7/169 (4%)
Frame = +3
Query: 90 CAIASAAECENATSLSLMIDSLLATYDRDSPPD---SKIVVNLTLHLRHAN-IRESESTV 257
CA S + N + + +D LL YD PD + V + + + + + E
Sbjct: 23 CA-QSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDIASIDMVSEVNMDY 81
Query: 258 RIQADLQMNWIDKRLSWNAGGVGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSN 437
+ Q W DKRLS+N + + +++LW PD LN + ++ R+
Sbjct: 82 TLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIR 141
Query: 438 ---NGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHTSDEMDF 575
+G+V + R+ + M L +P D Q CT + S +T+D+++F
Sbjct: 142 LHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEF 190
>BC099705-1|AAH99705.1| 474|Homo sapiens GABRB2 protein protein.
Length = 474
Score = 54.4 bits (125), Expect = 6e-07
Identities = 42/169 (24%), Positives = 75/169 (44%), Gaps = 7/169 (4%)
Frame = +3
Query: 90 CAIASAAECENATSLSLMIDSLLATYDRDSPPD---SKIVVNLTLHLRHAN-IRESESTV 257
CA S + N + + +D LL YD PD + V + + + + + E
Sbjct: 23 CA-QSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDIASIDMVSEVNMDY 81
Query: 258 RIQADLQMNWIDKRLSWNAGGVGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSN 437
+ Q W DKRLS+N + + +++LW PD LN + ++ R+
Sbjct: 82 TLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIR 141
Query: 438 ---NGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHTSDEMDF 575
+G+V + R+ + M L +P D Q CT + S +T+D+++F
Sbjct: 142 LHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEF 190
>X14767-1|CAA32875.1| 474|Homo sapiens GABA-A receptor beta 1
subunit protein.
Length = 474
Score = 54.0 bits (124), Expect = 7e-07
Identities = 41/169 (24%), Positives = 74/169 (43%), Gaps = 7/169 (4%)
Frame = +3
Query: 90 CAIASAAECENATSLSLMIDSLLATYDRDSPPD---SKIVVNLTLHLRHAN-IRESESTV 257
C S E N + +D LL YD PD + V + + + + + E
Sbjct: 23 CCAHSTNEPSNMPYVKETVDRLLKGYDIRLRPDFGGPPVDVGMRIDVASIDMVSEVNMDY 82
Query: 258 RIQADLQMNWIDKRLSWNAGGVGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSN 437
+ Q +W DKRLS++ + + +++LW PD LN + ++ R+
Sbjct: 83 TLTMYFQQSWKDKRLSYSGIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIR 142
Query: 438 ---NGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHTSDEMDF 575
+G+V + R+ + M L +P D Q CT + S +T+D+++F
Sbjct: 143 LHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEF 191
>BC028629-1|AAH28629.1| 492|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 3 protein.
Length = 492
Score = 54.0 bits (124), Expect = 7e-07
Identities = 37/158 (23%), Positives = 71/158 (44%), Gaps = 7/158 (4%)
Frame = +3
Query: 117 ENATSLSLMIDSLLATYDRDSPP---DSKIVVNLTLHLRHAN-IRESESTVRIQADLQMN 284
+N T + ++D LL YD P D+ V +++ + +++ I +
Sbjct: 62 DNITIFTRILDRLLDGYDNRLRPGLGDAVTEVKTDIYVTSFGPVSDTDMEYTIDVFFRQT 121
Query: 285 WIDKRLSWNAGGVGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSW 455
W D+RL ++ + + ++W PD N + A + R+ +NG++ +
Sbjct: 122 WHDERLKFDGPMKILPLNNLLASKIWTPDTFFHNGKKSVAHNMTTPNKLLRLVDNGTLPY 181
Query: 456 IKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHTSDEM 569
RL I M L+++P D+ C KFGS +T+ E+
Sbjct: 182 TMRLTIHAECPMHLEDFPMDVHACPLKFGSYAYTTAEV 219
>Z23141-1|CAA80672.1| 479|Homo sapiens cholinergic receptor,
nicotinic, alpha polypeptide 7 protein.
Length = 479
Score = 53.6 bits (123), Expect = 1e-06
Identities = 38/157 (24%), Positives = 71/157 (45%), Gaps = 3/157 (1%)
Frame = +3
Query: 174 DSPPDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWNAGGV-GCSTWLVSS 350
DS P + + +L+L L+ ++ E + LQM+W D L WN G T
Sbjct: 24 DSQPLT-VYFSLSL-LQIMDVDEKNQVLTTNIWLQMSWTDHYLQWNVSEYPGVKTVRFPD 81
Query: 351 ERLWRPDVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTC 527
++W+PD++L N+A + V+++G ++ + + + +P D+Q C
Sbjct: 82 GQIWKPDILLYNSADERFDATFHTNVLVNSSGHCQYLPPGIFKSSCYIDVRWFPFDVQHC 141
Query: 528 TFKFGSRMHTSDEMDFVIDKR-IYSMFESGPWDVTAL 635
KFGS + +D + + I +G WD+ +
Sbjct: 142 KLKFGSWSYGGWSLDLQMQEADISGYIPNGEWDLVGI 178
>Y08420-1|CAA69697.1| 502|Homo sapiens nicotinic acetylcholine
receptor alpha7 subunit precursor protein.
Length = 502
Score = 53.6 bits (123), Expect = 1e-06
Identities = 38/157 (24%), Positives = 71/157 (45%), Gaps = 3/157 (1%)
Frame = +3
Query: 174 DSPPDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWNAGGV-GCSTWLVSS 350
DS P + + +L+L L+ ++ E + LQM+W D L WN G T
Sbjct: 47 DSQPLT-VYFSLSL-LQIMDVDEKNQVLTTNIWLQMSWTDHYLQWNVSEYPGVKTVRFPD 104
Query: 351 ERLWRPDVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTC 527
++W+PD++L N+A + V+++G ++ + + + +P D+Q C
Sbjct: 105 GQIWKPDILLYNSADERFDATFHTNVLVNSSGHCQYLPPGIFKSSCYIDVRWFPFDVQHC 164
Query: 528 TFKFGSRMHTSDEMDFVIDKR-IYSMFESGPWDVTAL 635
KFGS + +D + + I +G WD+ +
Sbjct: 165 KLKFGSWSYGGWSLDLQMQEADISGYIPNGEWDLVGI 201
>X70297-1|CAA49778.1| 502|Homo sapiens neuronal nicotinic
acetylocholine receptor alpha-7 subunit protein.
Length = 502
Score = 53.6 bits (123), Expect = 1e-06
Identities = 38/157 (24%), Positives = 71/157 (45%), Gaps = 3/157 (1%)
Frame = +3
Query: 174 DSPPDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWNAGGV-GCSTWLVSS 350
DS P + + +L+L L+ ++ E + LQM+W D L WN G T
Sbjct: 47 DSQPLT-VYFSLSL-LQIMDVDEKNQVLTTNIWLQMSWTDHYLQWNVSEYPGVKTVRFPD 104
Query: 351 ERLWRPDVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTC 527
++W+PD++L N+A + V+++G ++ + + + +P D+Q C
Sbjct: 105 GQIWKPDILLYNSADERFDATFHTNVLVNSSGHCQYLPPGIFKSSCYIDVRWFPFDVQHC 164
Query: 528 TFKFGSRMHTSDEMDFVIDKR-IYSMFESGPWDVTAL 635
KFGS + +D + + I +G WD+ +
Sbjct: 165 KLKFGSWSYGGWSLDLQMQEADISGYIPNGEWDLVGI 201
>U62436-1|AAB40114.1| 502|Homo sapiens nicotinic acetylcholine
receptor alpha7 subunit precursor protein.
Length = 502
Score = 53.6 bits (123), Expect = 1e-06
Identities = 38/157 (24%), Positives = 71/157 (45%), Gaps = 3/157 (1%)
Frame = +3
Query: 174 DSPPDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWNAGGV-GCSTWLVSS 350
DS P + + +L+L L+ ++ E + LQM+W D L WN G T
Sbjct: 47 DSQPLT-VYFSLSL-LQIMDVDEKNQVLTTNIWLQMSWTDHYLQWNVSEYPGVKTVRFPD 104
Query: 351 ERLWRPDVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTC 527
++W+PD++L N+A + V+++G ++ + + + +P D+Q C
Sbjct: 105 GQIWKPDILLYNSADERFDATFHTNVLVNSSGHCQYLPPGIFKSSCYIDVRWFPFDVQHC 164
Query: 528 TFKFGSRMHTSDEMDFVIDKR-IYSMFESGPWDVTAL 635
KFGS + +D + + I +G WD+ +
Sbjct: 165 KLKFGSWSYGGWSLDLQMQEADISGYIPNGEWDLVGI 201
>S62908-1|AAB27279.1| 492|Homo sapiens gamma-aminobutyric acidA
receptor alpha 3 subunit protein.
Length = 492
Score = 53.6 bits (123), Expect = 1e-06
Identities = 37/158 (23%), Positives = 71/158 (44%), Gaps = 7/158 (4%)
Frame = +3
Query: 117 ENATSLSLMIDSLLATYDRDSPP---DSKIVVNLTLHLRHAN-IRESESTVRIQADLQMN 284
+N T + ++D LL YD P D+ V +++ + +++ I +
Sbjct: 62 DNITIFTRILDRLLDGYDNRLRPGLGDAVTEVKTDIYVTSFGPVSDTDMEYTIDVFFRQT 121
Query: 285 WIDKRLSWNAGGVGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSW 455
W D+RL ++ + + ++W PD N + A + R+ +NG++ +
Sbjct: 122 WHDERLKFDGPMKILPLNNLLASKIWTPDTFFHNGKKSVAHNMTTPNKLLRLVDNGTLLY 181
Query: 456 IKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHTSDEM 569
RL I M L+++P D+ C KFGS +T+ E+
Sbjct: 182 TMRLTIHAECPMHLEDFPMDVHACPLKFGSYAYTTAEV 219
>AJ586911-1|CAE52911.1| 502|Homo sapiens nicotinic acetylcholine
alpha-7 subunit protein.
Length = 502
Score = 53.6 bits (123), Expect = 1e-06
Identities = 38/157 (24%), Positives = 71/157 (45%), Gaps = 3/157 (1%)
Frame = +3
Query: 174 DSPPDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWNAGGV-GCSTWLVSS 350
DS P + + +L+L L+ ++ E + LQM+W D L WN G T
Sbjct: 47 DSQPLT-VYFSLSL-LQIMDVDEKNQVLTTNIWLQMSWTDHYLQWNVSEYPGVKTVRFPD 104
Query: 351 ERLWRPDVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTC 527
++W+PD++L N+A + V+++G ++ + + + +P D+Q C
Sbjct: 105 GQIWKPDILLYNSADERFDATFHTNVLVNSSGHCQYLPPGIFKSSCYIDVRWFPFDVQHC 164
Query: 528 TFKFGSRMHTSDEMDFVIDKR-IYSMFESGPWDVTAL 635
KFGS + +D + + I +G WD+ +
Sbjct: 165 KLKFGSWSYGGWSLDLQMQEADISGYIPNGEWDLVGI 201
>AF166361-1|AAG12455.1| 492|Homo sapiens GABA receptor subunit
alpha 3 protein.
Length = 492
Score = 53.6 bits (123), Expect = 1e-06
Identities = 37/158 (23%), Positives = 71/158 (44%), Gaps = 7/158 (4%)
Frame = +3
Query: 117 ENATSLSLMIDSLLATYDRDSPP---DSKIVVNLTLHLRHAN-IRESESTVRIQADLQMN 284
+N T + ++D LL YD P D+ V +++ + +++ I +
Sbjct: 62 DNITIFTRILDRLLDGYDNRLRPGLGDAVTEVKTDIYVTSFGPVSDTDMEYTIDVFFRQT 121
Query: 285 WIDKRLSWNAGGVGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSW 455
W D+RL ++ + + ++W PD N + A + R+ +NG++ +
Sbjct: 122 WHDERLKFDGPMKILPLNNLLASKIWTPDTFFHNGKKSVAHNMTTPNKLLRLVDNGTLLY 181
Query: 456 IKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHTSDEM 569
RL I M L+++P D+ C KFGS +T+ E+
Sbjct: 182 TMRLTIHAECPMHLEDFPMDVHACPLKFGSYAYTTAEV 219
>U77731-2|AAB38273.1| 360|Homo sapiens glycine receptor alpha 2B
subunit protein.
Length = 360
Score = 52.8 bits (121), Expect = 2e-06
Identities = 35/137 (25%), Positives = 63/137 (45%), Gaps = 6/137 (4%)
Frame = +3
Query: 183 PDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWNA---GGVGCSTWLVSSE 353
P + N+ ++ +I E+ R+ L+ W D RL+++ + ++ S
Sbjct: 69 PPVNVTCNIFIN-SFGSIAETTMDYRVNIFLRQQWNDSRLAYSEYPDDSLDLDPSMLDS- 126
Query: 354 RLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQT 524
+W+PD+ N D R+S NG V + RL ++ M L N+P D+QT
Sbjct: 127 -IWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNFPMDVQT 185
Query: 525 CTFKFGSRMHTSDEMDF 575
CT + S +T +++ F
Sbjct: 186 CTMQLESFGYTMNDLIF 202
>M82919-1|AAA52511.1| 473|Homo sapiens GABA-alpha receptor beta-3
subunit protein.
Length = 473
Score = 52.8 bits (121), Expect = 2e-06
Identities = 39/169 (23%), Positives = 74/169 (43%), Gaps = 7/169 (4%)
Frame = +3
Query: 90 CAIASAAECENATSLSLMIDSLLATYDRDSPPD---SKIVVNLTLHLRHAN-IRESESTV 257
C S + N + + +D LL YD PD + V + + + + + E
Sbjct: 23 CCAQSVNDPGNMSFVKETVDKLLKGYDIRLRPDFGGPPVCVGMNIDIASIDMVSEVNMDY 82
Query: 258 RIQADLQMNWIDKRLSWNAGGVGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSN 437
+ Q W DKRL+++ + + +++LW PD LN + ++ R+
Sbjct: 83 TLTMYFQQYWRDKRLAYSGIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIR 142
Query: 438 ---NGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHTSDEMDF 575
+G+V + R+ + M L +P D Q CT + S +T+D+++F
Sbjct: 143 LHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEF 191
>CR450343-1|CAG29339.1| 452|Homo sapiens GLRA2 protein.
Length = 452
Score = 52.8 bits (121), Expect = 2e-06
Identities = 35/137 (25%), Positives = 63/137 (45%), Gaps = 6/137 (4%)
Frame = +3
Query: 183 PDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWNA---GGVGCSTWLVSSE 353
P + N+ ++ +I E+ R+ L+ W D RL+++ + ++ S
Sbjct: 69 PPVNVTCNIFIN-SFGSIAETTMDYRVNIFLRQQWNDSRLAYSEYPDDSLDLDPSMLDS- 126
Query: 354 RLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQT 524
+W+PD+ N D R+S NG V + RL ++ M L N+P D+QT
Sbjct: 127 -IWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNFPMDVQT 185
Query: 525 CTFKFGSRMHTSDEMDF 575
CT + S +T +++ F
Sbjct: 186 CTMQLESFGYTMNDLIF 202
>AY437084-1|AAR87843.1| 452|Homo sapiens glycine receptor alpha2
subunit B protein.
Length = 452
Score = 52.8 bits (121), Expect = 2e-06
Identities = 35/137 (25%), Positives = 63/137 (45%), Gaps = 6/137 (4%)
Frame = +3
Query: 183 PDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWNA---GGVGCSTWLVSSE 353
P + N+ ++ +I E+ R+ L+ W D RL+++ + ++ S
Sbjct: 69 PPVNVTCNIFIN-SFGSIAETTMDYRVNIFLRQQWNDSRLAYSEYPDDSLDLDPSMLDS- 126
Query: 354 RLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQT 524
+W+PD+ N D R+S NG V + RL ++ M L N+P D+QT
Sbjct: 127 -IWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNFPMDVQT 185
Query: 525 CTFKFGSRMHTSDEMDF 575
CT + S +T +++ F
Sbjct: 186 CTMQLESFGYTMNDLIF 202
>X52008-1|CAA36257.1| 452|Homo sapiens inhibitory glycine receptor
protein.
Length = 452
Score = 52.4 bits (120), Expect = 2e-06
Identities = 34/137 (24%), Positives = 63/137 (45%), Gaps = 6/137 (4%)
Frame = +3
Query: 183 PDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWNA---GGVGCSTWLVSSE 353
P + N+ ++ ++ E+ R+ L+ W D RL+++ + ++ S
Sbjct: 69 PPVNVTCNIFIN-SFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPDDSLDLDPSMLDS- 126
Query: 354 RLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQT 524
+W+PD+ N D R+S NG V + RL ++ M L N+P D+QT
Sbjct: 127 -IWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNFPMDVQT 185
Query: 525 CTFKFGSRMHTSDEMDF 575
CT + S +T +++ F
Sbjct: 186 CTMQLESFGYTMNDLIF 202
>U77731-1|AAB38272.1| 360|Homo sapiens glycine receptor alpha 2
subunit protein.
Length = 360
Score = 52.4 bits (120), Expect = 2e-06
Identities = 34/137 (24%), Positives = 63/137 (45%), Gaps = 6/137 (4%)
Frame = +3
Query: 183 PDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWNA---GGVGCSTWLVSSE 353
P + N+ ++ ++ E+ R+ L+ W D RL+++ + ++ S
Sbjct: 69 PPVNVTCNIFIN-SFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPDDSLDLDPSMLDS- 126
Query: 354 RLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQT 524
+W+PD+ N D R+S NG V + RL ++ M L N+P D+QT
Sbjct: 127 -IWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNFPMDVQT 185
Query: 525 CTFKFGSRMHTSDEMDF 575
CT + S +T +++ F
Sbjct: 186 CTMQLESFGYTMNDLIF 202
>BC113575-1|AAI13576.1| 479|Homo sapiens cholinergic receptor,
nicotinic, alpha 9 protein.
Length = 479
Score = 52.4 bits (120), Expect = 2e-06
Identities = 43/184 (23%), Positives = 80/184 (43%), Gaps = 10/184 (5%)
Frame = +3
Query: 105 AAECENATSLSLMIDSLLATYDRDSPP--DSKIVVNLTLHLRHANIRESESTVRIQAD-- 272
AAE + + + L Y P D+ V+N+TL + + I++ + +I
Sbjct: 22 AAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQITLSQIKDMDERNQILTAYL 81
Query: 273 -LQMNWIDKRLSWNAGGV-GCSTWLVSSERLWRPDVVLLNAAATTAGD-YALRARVSNNG 443
++ W D L+W+ G + + S+ +WRPD+VL N A + + + +G
Sbjct: 82 WIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKADDESSEPVNTNVVLRYDG 141
Query: 444 SVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHTSDEMDF--VIDKRIYSMF-ESG 614
++W + + + +P D Q C FGS + +++D +D S F E
Sbjct: 142 LITWDAPAITKSSCVVDVTYFPFDNQQCNLTFGSWTYNGNQVDIFNALDSGDLSDFIEDV 201
Query: 615 PWDV 626
W+V
Sbjct: 202 EWEV 205
>BC113549-1|AAI13550.1| 479|Homo sapiens cholinergic receptor,
nicotinic, alpha 9 protein.
Length = 479
Score = 52.4 bits (120), Expect = 2e-06
Identities = 43/184 (23%), Positives = 80/184 (43%), Gaps = 10/184 (5%)
Frame = +3
Query: 105 AAECENATSLSLMIDSLLATYDRDSPP--DSKIVVNLTLHLRHANIRESESTVRIQAD-- 272
AAE + + + L Y P D+ V+N+TL + + I++ + +I
Sbjct: 22 AAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQITLSQIKDMDERNQILTAYL 81
Query: 273 -LQMNWIDKRLSWNAGGV-GCSTWLVSSERLWRPDVVLLNAAATTAGD-YALRARVSNNG 443
++ W D L+W+ G + + S+ +WRPD+VL N A + + + +G
Sbjct: 82 WIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKADDESSEPVNTNVVLRYDG 141
Query: 444 SVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHTSDEMDF--VIDKRIYSMF-ESG 614
++W + + + +P D Q C FGS + +++D +D S F E
Sbjct: 142 LITWDAPAITKSSCVVDVTYFPFDNQQCNLTFGSWTYNGNQVDIFNALDSGDLSDFIEDV 201
Query: 615 PWDV 626
W+V
Sbjct: 202 EWEV 205
>BC032864-1|AAH32864.1| 452|Homo sapiens glycine receptor, alpha 2
protein.
Length = 452
Score = 52.4 bits (120), Expect = 2e-06
Identities = 34/137 (24%), Positives = 63/137 (45%), Gaps = 6/137 (4%)
Frame = +3
Query: 183 PDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWNA---GGVGCSTWLVSSE 353
P + N+ ++ ++ E+ R+ L+ W D RL+++ + ++ S
Sbjct: 69 PPVNVTCNIFIN-SFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPDDSLDLDPSMLDS- 126
Query: 354 RLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQT 524
+W+PD+ N D R+S NG V + RL ++ M L N+P D+QT
Sbjct: 127 -IWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNFPMDVQT 185
Query: 525 CTFKFGSRMHTSDEMDF 575
CT + S +T +++ F
Sbjct: 186 CTMQLESFGYTMNDLIF 202
>AY437083-1|AAR87842.1| 452|Homo sapiens glycine receptor alpha2
subunit A protein.
Length = 452
Score = 52.4 bits (120), Expect = 2e-06
Identities = 34/137 (24%), Positives = 63/137 (45%), Gaps = 6/137 (4%)
Frame = +3
Query: 183 PDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWNA---GGVGCSTWLVSSE 353
P + N+ ++ ++ E+ R+ L+ W D RL+++ + ++ S
Sbjct: 69 PPVNVTCNIFIN-SFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPDDSLDLDPSMLDS- 126
Query: 354 RLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQT 524
+W+PD+ N D R+S NG V + RL ++ M L N+P D+QT
Sbjct: 127 -IWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNFPMDVQT 185
Query: 525 CTFKFGSRMHTSDEMDF 575
CT + S +T +++ F
Sbjct: 186 CTMQLESFGYTMNDLIF 202
>AY123244-1|AAM74523.1| 479|Homo sapiens nicotinic acetylcholine
receptor subunit alpha 9 protein.
Length = 479
Score = 52.4 bits (120), Expect = 2e-06
Identities = 43/184 (23%), Positives = 80/184 (43%), Gaps = 10/184 (5%)
Frame = +3
Query: 105 AAECENATSLSLMIDSLLATYDRDSPP--DSKIVVNLTLHLRHANIRESESTVRIQAD-- 272
AAE + + + L Y P D+ V+N+TL + + I++ + +I
Sbjct: 22 AAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQITLSQIKDMDERNQILTAYL 81
Query: 273 -LQMNWIDKRLSWNAGGV-GCSTWLVSSERLWRPDVVLLNAAATTAGD-YALRARVSNNG 443
++ W D L+W+ G + + S+ +WRPD+VL N A + + + +G
Sbjct: 82 WIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKADDESSEPVNTNVVLRYDG 141
Query: 444 SVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHTSDEMDF--VIDKRIYSMF-ESG 614
++W + + + +P D Q C FGS + +++D +D S F E
Sbjct: 142 LITWDAPAITKSSCVVDVTYFPFDNQQCNLTFGSWTYNGNQVDIFNALDSGDLSDFIEDV 201
Query: 615 PWDV 626
W+V
Sbjct: 202 EWEV 205
>AJ243342-1|CAB65091.1| 479|Homo sapiens nicotinic acetylcholine
receptor alpha 9 subunit protein.
Length = 479
Score = 52.4 bits (120), Expect = 2e-06
Identities = 43/184 (23%), Positives = 80/184 (43%), Gaps = 10/184 (5%)
Frame = +3
Query: 105 AAECENATSLSLMIDSLLATYDRDSPP--DSKIVVNLTLHLRHANIRESESTVRIQAD-- 272
AAE + + + L Y P D+ V+N+TL + + I++ + +I
Sbjct: 22 AAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQITLSQIKDMDERNQILTAYL 81
Query: 273 -LQMNWIDKRLSWNAGGV-GCSTWLVSSERLWRPDVVLLNAAATTAGD-YALRARVSNNG 443
++ W D L+W+ G + + S+ +WRPD+VL N A + + + +G
Sbjct: 82 WIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKADDESSEPVNTNVVLRYDG 141
Query: 444 SVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHTSDEMDF--VIDKRIYSMF-ESG 614
++W + + + +P D Q C FGS + +++D +D S F E
Sbjct: 142 LITWDAPAITKSSCVVDVTYFPFDNQQCNLTFGSWTYNGNQVDIFNALDSGDLSDFIEDV 201
Query: 615 PWDV 626
W+V
Sbjct: 202 EWEV 205
>AF227732-1|AAF61920.1| 470|Homo sapiens nicotinic acetylcholine
receptor alpha 9 subunit protein.
Length = 470
Score = 52.4 bits (120), Expect = 2e-06
Identities = 43/184 (23%), Positives = 80/184 (43%), Gaps = 10/184 (5%)
Frame = +3
Query: 105 AAECENATSLSLMIDSLLATYDRDSPP--DSKIVVNLTLHLRHANIRESESTVRIQAD-- 272
AAE + + + L Y P D+ V+N+TL + + I++ + +I
Sbjct: 16 AAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQITLSQIKDMDERNQILTAYL 75
Query: 273 -LQMNWIDKRLSWNAGGV-GCSTWLVSSERLWRPDVVLLNAAATTAGD-YALRARVSNNG 443
++ W D L+W+ G + + S+ +WRPD+VL N A + + + +G
Sbjct: 76 WIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKADDESSEPVNTNVVLRYDG 135
Query: 444 SVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHTSDEMDF--VIDKRIYSMF-ESG 614
++W + + + +P D Q C FGS + +++D +D S F E
Sbjct: 136 LITWDAPAITKSSCVVDVTYFPFDNQQCNLTFGSWTYNGNQVDIFNALDSGDLSDFIEDV 195
Query: 615 PWDV 626
W+V
Sbjct: 196 EWEV 199
>AF053495-1|AAC35290.1| 452|Homo sapiens glycine receptor alpha 2
subunit protein.
Length = 452
Score = 52.4 bits (120), Expect = 2e-06
Identities = 34/137 (24%), Positives = 63/137 (45%), Gaps = 6/137 (4%)
Frame = +3
Query: 183 PDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWNA---GGVGCSTWLVSSE 353
P + N+ ++ ++ E+ R+ L+ W D RL+++ + ++ S
Sbjct: 69 PPVNVTCNIFIN-SFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPDDSLDLDPSMLDS- 126
Query: 354 RLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQT 524
+W+PD+ N D R+S NG V + RL ++ M L N+P D+QT
Sbjct: 127 -IWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNFPMDVQT 185
Query: 525 CTFKFGSRMHTSDEMDF 575
CT + S +T +++ F
Sbjct: 186 CTMQLESFGYTMNDLIF 202
>AC118275-1|AAY40986.1| 479|Homo sapiens unknown protein.
Length = 479
Score = 52.4 bits (120), Expect = 2e-06
Identities = 43/184 (23%), Positives = 80/184 (43%), Gaps = 10/184 (5%)
Frame = +3
Query: 105 AAECENATSLSLMIDSLLATYDRDSPP--DSKIVVNLTLHLRHANIRESESTVRIQAD-- 272
AAE + + + L Y P D+ V+N+TL + + I++ + +I
Sbjct: 22 AAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQITLSQIKDMDERNQILTAYL 81
Query: 273 -LQMNWIDKRLSWNAGGV-GCSTWLVSSERLWRPDVVLLNAAATTAGD-YALRARVSNNG 443
++ W D L+W+ G + + S+ +WRPD+VL N A + + + +G
Sbjct: 82 WIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKADDESSEPVNTNVVLRYDG 141
Query: 444 SVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHTSDEMDF--VIDKRIYSMF-ESG 614
++W + + + +P D Q C FGS + +++D +D S F E
Sbjct: 142 LITWDAPAITKSSCVVDVTYFPFDNQQCNLTFGSWTYNGNQVDIFNALDSGDLSDFIEDV 201
Query: 615 PWDV 626
W+V
Sbjct: 202 EWEV 205
>U40583-1|AAA83561.1| 502|Homo sapiens alpha 7 neuronal nicotinic
acetylcholine receptor protein.
Length = 502
Score = 52.0 bits (119), Expect = 3e-06
Identities = 38/157 (24%), Positives = 69/157 (43%), Gaps = 3/157 (1%)
Frame = +3
Query: 174 DSPPDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWNAGGV-GCSTWLVSS 350
DS P + + +L L L+ ++ E + LQM+W D L WN G T
Sbjct: 47 DSQPLT-VYFSLNL-LQIMDVDEKNQVLTTNIWLQMSWTDHYLQWNVSEYPGVKTVRFPD 104
Query: 351 ERLWRPDVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTC 527
++W+PD++L N+A + V+ +G ++ + + + +P D+Q C
Sbjct: 105 GQIWKPDILLYNSADERFDATFHTNVLVNPSGHCQYLPPGIFKSSCYIDVRWFPFDVQHC 164
Query: 528 TFKFGSRMHTSDEMDFVIDKR-IYSMFESGPWDVTAL 635
KFGS + +D + + I +G WD+ +
Sbjct: 165 KLKFGSWSYGGWSLDLQMQEADISGYIPNGEWDLVGI 201
>AF385585-1|AAK68111.1| 502|Homo sapiens nicotinic cholinergic
receptor alpha 7 protein.
Length = 502
Score = 52.0 bits (119), Expect = 3e-06
Identities = 38/157 (24%), Positives = 69/157 (43%), Gaps = 3/157 (1%)
Frame = +3
Query: 174 DSPPDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWNAGGV-GCSTWLVSS 350
DS P + + +L L L+ ++ E + LQM+W D L WN G T
Sbjct: 47 DSQPLT-VYFSLNL-LQIMDVDEKNQVLTTNIWLQMSWTDHYLQWNVSEYPGVKTVRFPD 104
Query: 351 ERLWRPDVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTC 527
++W+PD++L N+A + V+ +G ++ + + + +P D+Q C
Sbjct: 105 GQIWKPDILLYNSADERFDATFHTNVLVNPSGHCQYLPPGIFKSSCYIDVRWFPFDVQHC 164
Query: 528 TFKFGSRMHTSDEMDFVIDKR-IYSMFESGPWDVTAL 635
KFGS + +D + + I +G WD+ +
Sbjct: 165 KLKFGSWSYGGWSLDLQMQEADISGYIPNGEWDLVGI 201
>U33267-1|AAB37750.1| 497|Homo sapiens glycine receptor beta
subunit protein.
Length = 497
Score = 51.6 bits (118), Expect = 4e-06
Identities = 42/163 (25%), Positives = 72/163 (44%), Gaps = 11/163 (6%)
Frame = +3
Query: 123 ATSLSLMIDSLLATYDRDSPPDSK-----IVVNLTLHLRHANIRESESTVRIQADLQMNW 287
A S S +++ LL +YD P+ K +VVN+ ++ +I+E+ R+ L+ W
Sbjct: 53 ANSTSNILNRLLVSYDPRIRPNFKGIPVDVVVNIFIN-SFGSIQETTMDYRVNIFLRQKW 111
Query: 288 IDKRLSWNAGGVGCSTWLVSSER---LWRPDVVLLNAAATTAGDYA---LRARVSNNGSV 449
D RL + G V LW+PD+ N + D + + +G V
Sbjct: 112 NDPRLKLPSDFRGSDALTVDPTMYKCLWKPDLFFANEKSANFHDVTQENILLFIFRDGDV 171
Query: 450 SWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHTSDEMDFV 578
RL I+ + L +P D Q C + S +T+D++ F+
Sbjct: 172 LVSMRLSITLSCPLDLTLFPMDTQRCKMQLESFGYTTDDLRFI 214
>BC032635-1|AAH32635.1| 497|Homo sapiens glycine receptor, beta
protein.
Length = 497
Score = 51.6 bits (118), Expect = 4e-06
Identities = 42/163 (25%), Positives = 72/163 (44%), Gaps = 11/163 (6%)
Frame = +3
Query: 123 ATSLSLMIDSLLATYDRDSPPDSK-----IVVNLTLHLRHANIRESESTVRIQADLQMNW 287
A S S +++ LL +YD P+ K +VVN+ ++ +I+E+ R+ L+ W
Sbjct: 53 ANSTSNILNRLLVSYDPRIRPNFKGIPVDVVVNIFIN-SFGSIQETTMDYRVNIFLRQKW 111
Query: 288 IDKRLSWNAGGVGCSTWLVSSER---LWRPDVVLLNAAATTAGDYA---LRARVSNNGSV 449
D RL + G V LW+PD+ N + D + + +G V
Sbjct: 112 NDPRLKLPSDFRGSDALTVDPTMYKCLWKPDLFFANEKSANFHDVTQENILLFIFRDGDV 171
Query: 450 SWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHTSDEMDFV 578
RL I+ + L +P D Q C + S +T+D++ F+
Sbjct: 172 LVSMRLSITLSCPLDLTLFPMDTQRCKMQLESFGYTTDDLRFI 214
>AF094755-1|AAC71034.1| 497|Homo sapiens glycine receptor beta
subunit precursor protein.
Length = 497
Score = 51.6 bits (118), Expect = 4e-06
Identities = 42/163 (25%), Positives = 72/163 (44%), Gaps = 11/163 (6%)
Frame = +3
Query: 123 ATSLSLMIDSLLATYDRDSPPDSK-----IVVNLTLHLRHANIRESESTVRIQADLQMNW 287
A S S +++ LL +YD P+ K +VVN+ ++ +I+E+ R+ L+ W
Sbjct: 53 ANSTSNILNRLLVSYDPRIRPNFKGIPVDVVVNIFIN-SFGSIQETTMDYRVNIFLRQKW 111
Query: 288 IDKRLSWNAGGVGCSTWLVSSER---LWRPDVVLLNAAATTAGDYA---LRARVSNNGSV 449
D RL + G V LW+PD+ N + D + + +G V
Sbjct: 112 NDPRLKLPSDFRGSDALTVDPTMYKCLWKPDLFFANEKSANFHDVTQENILLFIFRDGDV 171
Query: 450 SWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHTSDEMDFV 578
RL I+ + L +P D Q C + S +T+D++ F+
Sbjct: 172 LVSMRLSITLSCPLDLTLFPMDTQRCKMQLESFGYTTDDLRFI 214
>AF094754-1|AAC71033.1| 497|Homo sapiens glycine receptor beta
subunit precursor protein.
Length = 497
Score = 51.6 bits (118), Expect = 4e-06
Identities = 42/163 (25%), Positives = 72/163 (44%), Gaps = 11/163 (6%)
Frame = +3
Query: 123 ATSLSLMIDSLLATYDRDSPPDSK-----IVVNLTLHLRHANIRESESTVRIQADLQMNW 287
A S S +++ LL +YD P+ K +VVN+ ++ +I+E+ R+ L+ W
Sbjct: 53 ANSTSNILNRLLVSYDPRIRPNFKGIPVDVVVNIFIN-SFGSIQETTMDYRVNIFLRQKW 111
Query: 288 IDKRLSWNAGGVGCSTWLVSSER---LWRPDVVLLNAAATTAGDYA---LRARVSNNGSV 449
D RL + G V LW+PD+ N + D + + +G V
Sbjct: 112 NDPRLKLPSDFRGSDALTVDPTMYKCLWKPDLFFANEKSANFHDVTQENILLFIFRDGDV 171
Query: 450 SWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHTSDEMDFV 578
RL I+ + L +P D Q C + S +T+D++ F+
Sbjct: 172 LVSMRLSITLSCPLDLTLFPMDTQRCKMQLESFGYTTDDLRFI 214
>S82769-1|AAB39369.1| 467|Homo sapiens GABAA receptor gamma 3
subunit protein.
Length = 467
Score = 51.2 bits (117), Expect = 5e-06
Identities = 39/172 (22%), Positives = 71/172 (41%), Gaps = 7/172 (4%)
Frame = +3
Query: 126 TSLSLMIDSLLATYDRDSPPDSKI---VVNLTLHLRHAN-IRESESTVRIQADLQMNWID 293
T ++L+++ LL YD+ PD I V+++ +++ + +I W D
Sbjct: 45 TDVTLILNKLLREYDKKLRPDIGIKPTVIDVDIYVNSIGPVSSINMEYQIDIFFAQTWTD 104
Query: 294 KRLSWNAGGVGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKR 464
RL +N+ + +W PD + N+ A R+ N+G + + R
Sbjct: 105 SRLRFNSTMKILTLNSNMVGLIWIPDTIFRNSKTAEAHWITTPNQLLRIWNDGKILYTLR 164
Query: 465 LDISTPISMQLDNWPNDMQTCTFKFGSRMHTSDEMDFVIDKRIYSMFESGPW 620
L I+ +QL N+P D +C F S + +EM + K + W
Sbjct: 165 LTINAECQLQLHNFPMDEHSCPLIFSSYGYPKEEMIYRWRKNSVEAADQKSW 216
>AK122638-1|BAC85499.1| 266|Homo sapiens yte protein of 76kDa)
(LCP2). protein.
Length = 266
Score = 51.2 bits (117), Expect = 5e-06
Identities = 27/95 (28%), Positives = 45/95 (47%)
Frame = +3
Query: 273 LQMNWIDKRLSWNAGGVGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVS 452
L+++W+D RL+WN + E LW P + +L A D + +ARV +G V
Sbjct: 87 LRLSWLDTRLAWNTSAHPRHAITLPWESLWTPRLTILEALWVDWRDQSPQARVDQDGHVK 146
Query: 453 WIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHT 557
L T + +L ++P D C+ F + +T
Sbjct: 147 LNLALTTETNCNFELLHFPRDHSNCSLSFYALSNT 181
>AF269144-1|AAF99698.1| 467|Homo sapiens GABAA receptor gamma 3
subunit protein.
Length = 467
Score = 51.2 bits (117), Expect = 5e-06
Identities = 39/172 (22%), Positives = 71/172 (41%), Gaps = 7/172 (4%)
Frame = +3
Query: 126 TSLSLMIDSLLATYDRDSPPDSKI---VVNLTLHLRHAN-IRESESTVRIQADLQMNWID 293
T ++L+++ LL YD+ PD I V+++ +++ + +I W D
Sbjct: 45 TDVTLILNKLLREYDKKLRPDIGIKPTVIDVDIYVNSIGPVSSINMEYQIDIFFAQTWTD 104
Query: 294 KRLSWNAGGVGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKR 464
RL +N+ + +W PD + N+ A R+ N+G + + R
Sbjct: 105 SRLRFNSTMKILTLNSNMVGLIWIPDTIFRNSKTAEAHWITTPNQLLRIWNDGKILYTLR 164
Query: 465 LDISTPISMQLDNWPNDMQTCTFKFGSRMHTSDEMDFVIDKRIYSMFESGPW 620
L I+ +QL N+P D +C F S + +EM + K + W
Sbjct: 165 LTINAECQLQLHNFPMDEHSCPLIFSSYGYPKEEMIYRWRKNSVEAADQKSW 216
>AF228458-1|AAF63215.1| 449|Homo sapiens GABAA receptor gamma 3
subunit protein.
Length = 449
Score = 51.2 bits (117), Expect = 5e-06
Identities = 39/172 (22%), Positives = 71/172 (41%), Gaps = 7/172 (4%)
Frame = +3
Query: 126 TSLSLMIDSLLATYDRDSPPDSKI---VVNLTLHLRHAN-IRESESTVRIQADLQMNWID 293
T ++L+++ LL YD+ PD I V+++ +++ + +I W D
Sbjct: 27 TDVTLILNKLLREYDKKLRPDIGIKPTVIDVDIYVNSIGPVSSINMEYQIDIFFAQTWTD 86
Query: 294 KRLSWNAGGVGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKR 464
RL +N+ + +W PD + N+ A R+ N+G + + R
Sbjct: 87 SRLRFNSTMKILTLNSNMVGLIWIPDTIFRNSKTAEAHWITTPNQLLRIWNDGKILYTLR 146
Query: 465 LDISTPISMQLDNWPNDMQTCTFKFGSRMHTSDEMDFVIDKRIYSMFESGPW 620
L I+ +QL N+P D +C F S + +EM + K + W
Sbjct: 147 LTINAECQLQLHNFPMDEHSCPLIFSSYGYPKEEMIYRWRKNSVEAADQKSW 198
>S81944-1|AAB36480.1| 453|Homo sapiens gamma-aminobutyric acid type
A receptor alpha 6 subunit protein.
Length = 453
Score = 50.4 bits (115), Expect = 9e-06
Identities = 39/166 (23%), Positives = 71/166 (42%), Gaps = 8/166 (4%)
Frame = +3
Query: 129 SLSLMIDSLLATYDRDSPPD---SKIVVNLTLHLRHAN-IRESESTVRIQADLQMNWIDK 296
++S ++D+LL YD P + V +++ + + E + + W D+
Sbjct: 31 NVSRILDNLLEGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTDE 90
Query: 297 RLSWNAGGVGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRA---RVSNNGSVSWIKRL 467
RL + S + ++W PD N + A + R+ NG++ + RL
Sbjct: 91 RLKFGGPTEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTMRL 150
Query: 468 DISTPISMQLDNWPNDMQTCTFKFGSRMHTSDEMDFVIDK-RIYSM 602
I+ M+L N+P D C KFGS + E+ + K +YS+
Sbjct: 151 TINADCPMRLVNFPMDGHACPLKFGSYAYPKSEIIYTWKKGPLYSV 196
>BC099641-1|AAH99641.1| 453|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 6 protein.
Length = 453
Score = 50.4 bits (115), Expect = 9e-06
Identities = 39/166 (23%), Positives = 71/166 (42%), Gaps = 8/166 (4%)
Frame = +3
Query: 129 SLSLMIDSLLATYDRDSPPD---SKIVVNLTLHLRHAN-IRESESTVRIQADLQMNWIDK 296
++S ++D+LL YD P + V +++ + + E + + W D+
Sbjct: 31 NVSRILDNLLEGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTDE 90
Query: 297 RLSWNAGGVGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRA---RVSNNGSVSWIKRL 467
RL + S + ++W PD N + A + R+ NG++ + RL
Sbjct: 91 RLKFGGPTEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTMRL 150
Query: 468 DISTPISMQLDNWPNDMQTCTFKFGSRMHTSDEMDFVIDK-RIYSM 602
I+ M+L N+P D C KFGS + E+ + K +YS+
Sbjct: 151 TINADCPMRLVNFPMDGHACPLKFGSYAYPKSEIIYTWKKGPLYSV 196
>BC099640-1|AAH99640.1| 453|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 6 protein.
Length = 453
Score = 50.4 bits (115), Expect = 9e-06
Identities = 39/166 (23%), Positives = 71/166 (42%), Gaps = 8/166 (4%)
Frame = +3
Query: 129 SLSLMIDSLLATYDRDSPPD---SKIVVNLTLHLRHAN-IRESESTVRIQADLQMNWIDK 296
++S ++D+LL YD P + V +++ + + E + + W D+
Sbjct: 31 NVSRILDNLLEGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTDE 90
Query: 297 RLSWNAGGVGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRA---RVSNNGSVSWIKRL 467
RL + S + ++W PD N + A + R+ NG++ + RL
Sbjct: 91 RLKFGGPTEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTMRL 150
Query: 468 DISTPISMQLDNWPNDMQTCTFKFGSRMHTSDEMDFVIDK-RIYSM 602
I+ M+L N+P D C KFGS + E+ + K +YS+
Sbjct: 151 TINADCPMRLVNFPMDGHACPLKFGSYAYPKSEIIYTWKKGPLYSV 196
>BC096242-1|AAH96242.1| 453|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 6 protein.
Length = 453
Score = 50.4 bits (115), Expect = 9e-06
Identities = 39/166 (23%), Positives = 71/166 (42%), Gaps = 8/166 (4%)
Frame = +3
Query: 129 SLSLMIDSLLATYDRDSPPD---SKIVVNLTLHLRHAN-IRESESTVRIQADLQMNWIDK 296
++S ++D+LL YD P + V +++ + + E + + W D+
Sbjct: 31 NVSRILDNLLEGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTDE 90
Query: 297 RLSWNAGGVGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRA---RVSNNGSVSWIKRL 467
RL + S + ++W PD N + A + R+ NG++ + RL
Sbjct: 91 RLKFGGPTEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTMRL 150
Query: 468 DISTPISMQLDNWPNDMQTCTFKFGSRMHTSDEMDFVIDK-RIYSM 602
I+ M+L N+P D C KFGS + E+ + K +YS+
Sbjct: 151 TINADCPMRLVNFPMDGHACPLKFGSYAYPKSEIIYTWKKGPLYSV 196
>BC096241-1|AAH96241.1| 453|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 6 protein.
Length = 453
Score = 50.4 bits (115), Expect = 9e-06
Identities = 39/166 (23%), Positives = 71/166 (42%), Gaps = 8/166 (4%)
Frame = +3
Query: 129 SLSLMIDSLLATYDRDSPPD---SKIVVNLTLHLRHAN-IRESESTVRIQADLQMNWIDK 296
++S ++D+LL YD P + V +++ + + E + + W D+
Sbjct: 31 NVSRILDNLLEGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTDE 90
Query: 297 RLSWNAGGVGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRA---RVSNNGSVSWIKRL 467
RL + S + ++W PD N + A + R+ NG++ + RL
Sbjct: 91 RLKFGGPTEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTMRL 150
Query: 468 DISTPISMQLDNWPNDMQTCTFKFGSRMHTSDEMDFVIDK-RIYSM 602
I+ M+L N+P D C KFGS + E+ + K +YS+
Sbjct: 151 TINADCPMRLVNFPMDGHACPLKFGSYAYPKSEIIYTWKKGPLYSV 196
>BC010641-1|AAH10641.1| 473|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, beta 3 protein.
Length = 473
Score = 50.0 bits (114), Expect = 1e-05
Identities = 38/169 (22%), Positives = 73/169 (43%), Gaps = 7/169 (4%)
Frame = +3
Query: 90 CAIASAAECENATSLSLMIDSLLATYDRDSPPD---SKIVVNLTLHLRHAN-IRESESTV 257
C S + N + + +D LL YD PD + V + + + + + E
Sbjct: 23 CCAQSVNDPGNMSFVKETVDKLLKGYDIRLRPDFGGPPVCVGMNIDIASIDMVSEVNMDY 82
Query: 258 RIQADLQMNWIDKRLSWNAGGVGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSN 437
+ Q W DKRL+++ + + +++LW PD LN + ++ R+
Sbjct: 83 TLTMYFQQYWRDKRLAYSGIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIR 142
Query: 438 ---NGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHTSDEMDF 575
+G+V + R+ + M L +P D CT + S +T+D+++F
Sbjct: 143 LHPDGTVLYGLRITTTAACMMDLRRYPLDELNCTLEIESYGYTTDDIEF 191
>AJ003080-1|CAA05853.1| 238|Homo sapiens serotonin receptor
protein.
Length = 238
Score = 50.0 bits (114), Expect = 1e-05
Identities = 28/111 (25%), Positives = 48/111 (43%), Gaps = 1/111 (0%)
Frame = +3
Query: 231 NIRESESTVRIQADLQMNWIDKRLSWNAGGVGCSTWL-VSSERLWRPDVVLLNAAATTAG 407
N+ E + + W D+ L WN T L + ++ +W PD+++
Sbjct: 72 NVDEKNQVLTTYIWYRQYWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKS 131
Query: 408 DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHTS 560
+ + G V K L + T S+ + N+P D+Q C+ F S +HTS
Sbjct: 132 PNIPYVYIRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLHTS 182
>U30461-1|AAB52519.1| 554|Homo sapiens GABAA receptor subunit
alpha4 protein.
Length = 554
Score = 49.6 bits (113), Expect = 2e-05
Identities = 39/157 (24%), Positives = 68/157 (43%), Gaps = 8/157 (5%)
Frame = +3
Query: 141 MIDSLLATYD-RDSP----PDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLS 305
++DSLL YD R P P +++ ++ + + + E + + WIDKRL
Sbjct: 51 ILDSLLDGYDNRLRPGFGGPVTEVKTDIYV-TSFGPVSDVEMEYTMDVFFRQTWIDKRLK 109
Query: 306 WNAGGVGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRA---RVSNNGSVSWIKRLDIS 476
++ + ++W PD N + + + R+ NG++ + RL IS
Sbjct: 110 YDGPIEILRLNNMMVTKVWTPDTFFRNGKKSVSHNMTAPNKLFRIMRNGTILYTMRLTIS 169
Query: 477 TPISMQLDNWPNDMQTCTFKFGSRMHTSDEMDFVIDK 587
M+L ++P D C KFGS + EM + K
Sbjct: 170 AECPMRLVDFPMDGHACPLKFGSYAYPKSEMIYTWTK 206
>S82612-1|AAB37533.2| 478|Homo sapiens 5-hydroxytryptamine type 3AS
receptor subunit protein.
Length = 478
Score = 49.6 bits (113), Expect = 2e-05
Identities = 27/115 (23%), Positives = 50/115 (43%), Gaps = 1/115 (0%)
Frame = +3
Query: 231 NIRESESTVRIQADLQMNWIDKRLSWNAGGVGCSTWL-VSSERLWRPDVVLLNAAATTAG 407
N+ E + + W D+ L WN T L + ++ +W PD+++
Sbjct: 72 NVDEKNQVLTTYIWYRQYWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINELVDVGKS 131
Query: 408 DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHTSDEMD 572
+ + G V K L + T S+ + N+P D+Q C+ F S +HT +++
Sbjct: 132 PNIPYVYIRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLHTIQDIN 186
>BC035055-1|AAH35055.1| 554|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 4 protein.
Length = 554
Score = 49.6 bits (113), Expect = 2e-05
Identities = 39/157 (24%), Positives = 68/157 (43%), Gaps = 8/157 (5%)
Frame = +3
Query: 141 MIDSLLATYD-RDSP----PDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLS 305
++DSLL YD R P P +++ ++ + + + E + + WIDKRL
Sbjct: 51 ILDSLLDGYDNRLRPGFGGPVTEVKTDIYV-TSFGPVSDVEMEYTMDVFFRQTWIDKRLK 109
Query: 306 WNAGGVGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRA---RVSNNGSVSWIKRLDIS 476
++ + ++W PD N + + + R+ NG++ + RL IS
Sbjct: 110 YDGPIEILRLNNMMVTKVWTPDTFFRNGKKSVSHNMTAPNKLFRIMRNGTILYTMRLTIS 169
Query: 477 TPISMQLDNWPNDMQTCTFKFGSRMHTSDEMDFVIDK 587
M+L ++P D C KFGS + EM + K
Sbjct: 170 AECPMRLVDFPMDGHACPLKFGSYAYPKSEMIYTWTK 206
>BC022449-1|AAH22449.1| 474|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, beta 1 protein.
Length = 474
Score = 49.6 bits (113), Expect = 2e-05
Identities = 40/169 (23%), Positives = 74/169 (43%), Gaps = 7/169 (4%)
Frame = +3
Query: 90 CAIASAAECENATSLSLMIDSLLATYDRDSPPD---SKIVVNLTLHLRHAN-IRESESTV 257
C S E N + + +D LL YD PD + V + + + + + E
Sbjct: 23 CCAHSTNEPSNMSYVKETVDRLLKGYDIRLRPDFGGPPVDVGMRIDVASIDMVSEVNMDY 82
Query: 258 RIQADLQMNWIDKRLSWNAGGVGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSN 437
+ Q +W DKRLS++ + + +++L PD LN + ++ R+
Sbjct: 83 TLTMYFQQSWKDKRLSYSGIPLNLTLDNRVADQLCVPDTYFLNDKKSFVHGVTVKNRMIR 142
Query: 438 ---NGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHTSDEMDF 575
+G+V + R+ + M L +P D Q CT + S +T+D+++F
Sbjct: 143 LHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEF 191
>D49394-1|BAA08387.1| 478|Homo sapiens serotonin 5-HT3 receptor
protein.
Length = 478
Score = 49.2 bits (112), Expect = 2e-05
Identities = 27/115 (23%), Positives = 50/115 (43%), Gaps = 1/115 (0%)
Frame = +3
Query: 231 NIRESESTVRIQADLQMNWIDKRLSWNAGGVGCSTWL-VSSERLWRPDVVLLNAAATTAG 407
N+ E + + W D+ L WN T L + ++ +W PD+++
Sbjct: 72 NVDEKNQVLTTYIWYRQYWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKS 131
Query: 408 DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHTSDEMD 572
+ + G V K L + T S+ + N+P D+Q C+ F S +HT +++
Sbjct: 132 PNIPYVYIRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLHTIQDIN 186
>BT007204-1|AAP35868.1| 484|Homo sapiens 5-hydroxytryptamine
(serotonin) receptor 3A protein.
Length = 484
Score = 49.2 bits (112), Expect = 2e-05
Identities = 27/115 (23%), Positives = 50/115 (43%), Gaps = 1/115 (0%)
Frame = +3
Query: 231 NIRESESTVRIQADLQMNWIDKRLSWNAGGVGCSTWL-VSSERLWRPDVVLLNAAATTAG 407
N+ E + + W D+ L WN T L + ++ +W PD+++
Sbjct: 78 NVDEKNQVLTTYIWYRQYWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKS 137
Query: 408 DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHTSDEMD 572
+ + G V K L + T S+ + N+P D+Q C+ F S +HT +++
Sbjct: 138 PNIPYVYIRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLHTIQDIN 192
>BC004453-1|AAH04453.2| 478|Homo sapiens 5-hydroxytryptamine
(serotonin) receptor 3A protein.
Length = 478
Score = 49.2 bits (112), Expect = 2e-05
Identities = 27/115 (23%), Positives = 50/115 (43%), Gaps = 1/115 (0%)
Frame = +3
Query: 231 NIRESESTVRIQADLQMNWIDKRLSWNAGGVGCSTWL-VSSERLWRPDVVLLNAAATTAG 407
N+ E + + W D+ L WN T L + ++ +W PD+++
Sbjct: 72 NVDEKNQVLTTYIWYRQYWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKS 131
Query: 408 DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHTSDEMD 572
+ + G V K L + T S+ + N+P D+Q C+ F S +HT +++
Sbjct: 132 PNIPYVYIRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLHTIQDIN 186
>BC002354-1|AAH02354.1| 478|Homo sapiens 5-hydroxytryptamine
(serotonin) receptor 3A protein.
Length = 478
Score = 49.2 bits (112), Expect = 2e-05
Identities = 27/115 (23%), Positives = 50/115 (43%), Gaps = 1/115 (0%)
Frame = +3
Query: 231 NIRESESTVRIQADLQMNWIDKRLSWNAGGVGCSTWL-VSSERLWRPDVVLLNAAATTAG 407
N+ E + + W D+ L WN T L + ++ +W PD+++
Sbjct: 72 NVDEKNQVLTTYIWYRQYWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKS 131
Query: 408 DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHTSDEMD 572
+ + G V K L + T S+ + N+P D+Q C+ F S +HT +++
Sbjct: 132 PNIPYVYIRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLHTIQDIN 186
>AJ005205-1|CAA06442.3| 478|Homo sapiens serotonin 3 receptor
protein.
Length = 478
Score = 49.2 bits (112), Expect = 2e-05
Identities = 27/115 (23%), Positives = 50/115 (43%), Gaps = 1/115 (0%)
Frame = +3
Query: 231 NIRESESTVRIQADLQMNWIDKRLSWNAGGVGCSTWL-VSSERLWRPDVVLLNAAATTAG 407
N+ E + + W D+ L WN T L + ++ +W PD+++
Sbjct: 72 NVDEKNQVLTTYIWYRQYWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKS 131
Query: 408 DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHTSDEMD 572
+ + G V K L + T S+ + N+P D+Q C+ F S +HT +++
Sbjct: 132 PNIPYVYIRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLHTIQDIN 186
>AJ003079-1|CAA05852.1| 478|Homo sapiens 5-hydroxytryptamine3
receptor protein.
Length = 478
Score = 49.2 bits (112), Expect = 2e-05
Identities = 27/115 (23%), Positives = 50/115 (43%), Gaps = 1/115 (0%)
Frame = +3
Query: 231 NIRESESTVRIQADLQMNWIDKRLSWNAGGVGCSTWL-VSSERLWRPDVVLLNAAATTAG 407
N+ E + + W D+ L WN T L + ++ +W PD+++
Sbjct: 72 NVDEKNQVLTTYIWYRQYWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKS 131
Query: 408 DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHTSDEMD 572
+ + G V K L + T S+ + N+P D+Q C+ F S +HT +++
Sbjct: 132 PNIPYVYIRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLHTIQDIN 186
>AJ003078-1|CAA05851.1| 510|Homo sapiens serotonin receptor
protein.
Length = 510
Score = 49.2 bits (112), Expect = 2e-05
Identities = 27/115 (23%), Positives = 50/115 (43%), Gaps = 1/115 (0%)
Frame = +3
Query: 231 NIRESESTVRIQADLQMNWIDKRLSWNAGGVGCSTWL-VSSERLWRPDVVLLNAAATTAG 407
N+ E + + W D+ L WN T L + ++ +W PD+++
Sbjct: 72 NVDEKNQVLTTYIWYRQYWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKS 131
Query: 408 DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHTSDEMD 572
+ + G V K L + T S+ + N+P D+Q C+ F S +HT +++
Sbjct: 132 PNIPYVYIRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLHTIQDIN 186
>AF498984-1|AAM21131.1| 478|Homo sapiens 5-hydroxytryptamine
receptor 3A protein.
Length = 478
Score = 49.2 bits (112), Expect = 2e-05
Identities = 27/115 (23%), Positives = 50/115 (43%), Gaps = 1/115 (0%)
Frame = +3
Query: 231 NIRESESTVRIQADLQMNWIDKRLSWNAGGVGCSTWL-VSSERLWRPDVVLLNAAATTAG 407
N+ E + + W D+ L WN T L + ++ +W PD+++
Sbjct: 72 NVDEKNQVLTTYIWYRQYWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKS 131
Query: 408 DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHTSDEMD 572
+ + G V K L + T S+ + N+P D+Q C+ F S +HT +++
Sbjct: 132 PNIPYVYIRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLHTIQDIN 186
>BC111802-1|AAI11803.1| 465|Homo sapiens CHRNG protein protein.
Length = 465
Score = 48.8 bits (111), Expect = 3e-05
Identities = 33/113 (29%), Positives = 53/113 (46%), Gaps = 7/113 (6%)
Frame = +3
Query: 141 MIDSLLATYDRDSPPDSKI--VVNLTLHLRHANI---RESESTVRIQADLQMNWIDKRLS 305
++ L+ YD + P + VVN++L L N+ E E + ++M W D RL
Sbjct: 29 LLADLMQNYDPNLRPAERDSDVVNVSLKLTLTNLISLNEREEALTTNVWIEMQWCDYRLR 88
Query: 306 WNAGGV-GCSTWLVSSERLWRPDVVLLNAAAT-TAGDYALRARVSNNGSVSWI 458
W+ G V S +WRPD+VL N + T + + L+ + S+ WI
Sbjct: 89 WDPRDYEGLWVLRVPSTMVWRPDIVLENKSQTYSTNEIDLQLSQEDGQSIEWI 141
>X52009-1|CAA36258.1| 449|Homo sapiens inhibitory glycine receptor
protein.
Length = 449
Score = 48.4 bits (110), Expect = 4e-05
Identities = 31/121 (25%), Positives = 57/121 (47%), Gaps = 6/121 (4%)
Frame = +3
Query: 231 NIRESESTVRIQADLQMNWIDKRLSWNA---GGVGCSTWLVSSERLWRPDVVLLNAAATT 401
+I E+ R+ L+ W D RL++N + ++ S +W+PD+ N
Sbjct: 78 SIAETTMDYRVNIFLRQQWNDPRLAYNEYPDDSLDLDPSMLDS--IWKPDLFFANEKGAH 135
Query: 402 AGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHTSDEMD 572
+ R+S NG+V + R+ ++ M L N+P D+QTC + S +T +++
Sbjct: 136 FHEITTDNKLLRISRNGNVLYSIRITLTLACPMDLKNFPMDVQTCIMQLESFGYTMNDLI 195
Query: 573 F 575
F
Sbjct: 196 F 196
>BC114947-1|AAI14948.1| 457|Homo sapiens GLRA1 protein protein.
Length = 457
Score = 48.4 bits (110), Expect = 4e-05
Identities = 31/121 (25%), Positives = 57/121 (47%), Gaps = 6/121 (4%)
Frame = +3
Query: 231 NIRESESTVRIQADLQMNWIDKRLSWNA---GGVGCSTWLVSSERLWRPDVVLLNAAATT 401
+I E+ R+ L+ W D RL++N + ++ S +W+PD+ N
Sbjct: 78 SIAETTMDYRVNIFLRQQWNDPRLAYNEYPDDSLDLDPSMLDS--IWKPDLFFANEKGAH 135
Query: 402 AGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHTSDEMD 572
+ R+S NG+V + R+ ++ M L N+P D+QTC + S +T +++
Sbjct: 136 FHEITTDNKLLRISRNGNVLYSIRITLTLACPMDLKNFPMDVQTCIMQLESFGYTMNDLI 195
Query: 573 F 575
F
Sbjct: 196 F 196
>BC109211-1|AAI09212.1| 632|Homo sapiens gamma-aminobutyric acid
(GABA) receptor, theta protein.
Length = 632
Score = 48.4 bits (110), Expect = 4e-05
Identities = 37/159 (23%), Positives = 67/159 (42%), Gaps = 7/159 (4%)
Frame = +3
Query: 114 CENATSLSLMIDSLLATYDRDSPPD---SKIVVNLTLHLRHAN-IRESESTVRIQADLQM 281
C N + ++D +L+ YD P+ + + V +++++ I E I
Sbjct: 53 CANEAVVQKILDRVLSRYDVRLRPNFGGAPVPVRISIYVTSIEQISEMNMDYTITMFFHQ 112
Query: 282 NWIDKRLSWNAGGVGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSN---NGSVS 452
W D RL++ + + E+LW PD LN+ D + RV +G+V
Sbjct: 113 TWKDSRLAYYETTLNLTLDYRMHEKLWVPDCYFLNSKDAFVHDVTVENRVFQLHPDGTVR 172
Query: 453 WIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHTSDEM 569
+ RL + S+ L +P D Q C S +T +++
Sbjct: 173 YGIRLTTTAACSLDLHKFPMDKQACNLVVESYGYTVEDI 211
>BC109210-1|AAI09211.1| 632|Homo sapiens gamma-aminobutyric acid
(GABA) receptor, theta protein.
Length = 632
Score = 48.4 bits (110), Expect = 4e-05
Identities = 37/159 (23%), Positives = 67/159 (42%), Gaps = 7/159 (4%)
Frame = +3
Query: 114 CENATSLSLMIDSLLATYDRDSPPD---SKIVVNLTLHLRHAN-IRESESTVRIQADLQM 281
C N + ++D +L+ YD P+ + + V +++++ I E I
Sbjct: 53 CANEAVVQKILDRVLSRYDVRLRPNFGGAPVPVRISIYVTSIEQISEMNMDYTITMFFHQ 112
Query: 282 NWIDKRLSWNAGGVGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSN---NGSVS 452
W D RL++ + + E+LW PD LN+ D + RV +G+V
Sbjct: 113 TWKDSRLAYYETTLNLTLDYRMHEKLWVPDCYFLNSKDAFVHDVTVENRVFQLHPDGTVR 172
Query: 453 WIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHTSDEM 569
+ RL + S+ L +P D Q C S +T +++
Sbjct: 173 YGIRLTTTAACSLDLHKFPMDKQACNLVVESYGYTVEDI 211
>BC074980-1|AAH74980.1| 449|Homo sapiens glycine receptor, alpha 1
(startle disease/hyperekplexia) protein.
Length = 449
Score = 48.4 bits (110), Expect = 4e-05
Identities = 31/121 (25%), Positives = 57/121 (47%), Gaps = 6/121 (4%)
Frame = +3
Query: 231 NIRESESTVRIQADLQMNWIDKRLSWNA---GGVGCSTWLVSSERLWRPDVVLLNAAATT 401
+I E+ R+ L+ W D RL++N + ++ S +W+PD+ N
Sbjct: 78 SIAETTMDYRVNIFLRQQWNDPRLAYNEYPDDSLDLDPSMLDS--IWKPDLFFANEKGAH 135
Query: 402 AGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHTSDEMD 572
+ R+S NG+V + R+ ++ M L N+P D+QTC + S +T +++
Sbjct: 136 FHEITTDNKLLRISRNGNVLYSIRITLTLACPMDLKNFPMDVQTCIMQLESFGYTMNDLI 195
Query: 573 F 575
F
Sbjct: 196 F 196
>AF189259-1|AAF70380.1| 632|Homo sapiens GABA-A receptor theta
subunit protein.
Length = 632
Score = 48.4 bits (110), Expect = 4e-05
Identities = 37/159 (23%), Positives = 67/159 (42%), Gaps = 7/159 (4%)
Frame = +3
Query: 114 CENATSLSLMIDSLLATYDRDSPPD---SKIVVNLTLHLRHAN-IRESESTVRIQADLQM 281
C N + ++D +L+ YD P+ + + V +++++ I E I
Sbjct: 53 CANEAVVQKILDRVLSRYDVRLRPNFGGAPVPVRISIYVTSIEQISEMNMDYTITMFFHQ 112
Query: 282 NWIDKRLSWNAGGVGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSN---NGSVS 452
W D RL++ + + E+LW PD LN+ D + RV +G+V
Sbjct: 113 TWKDSRLAYYETTLNLTLDYRMHEKLWVPDCYFLNSKDAFVHDVTVENRVFQLHPDGTVR 172
Query: 453 WIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHTSDEM 569
+ RL + S+ L +P D Q C S +T +++
Sbjct: 173 YGIRLTTTAACSLDLHKFPMDKQACNLVVESYGYTVEDI 211
>AF144648-1|AAD51172.1| 627|Homo sapiens GABA-A receptor theta
protein.
Length = 627
Score = 48.4 bits (110), Expect = 4e-05
Identities = 37/159 (23%), Positives = 67/159 (42%), Gaps = 7/159 (4%)
Frame = +3
Query: 114 CENATSLSLMIDSLLATYDRDSPPD---SKIVVNLTLHLRHAN-IRESESTVRIQADLQM 281
C N + ++D +L+ YD P+ + + V +++++ I E I
Sbjct: 48 CANEAVVQKILDRVLSRYDVRLRPNFGGAPVPVRISIYVTSIEQISEMNMDYTITMFFHQ 107
Query: 282 NWIDKRLSWNAGGVGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSN---NGSVS 452
W D RL++ + + E+LW PD LN+ D + RV +G+V
Sbjct: 108 TWKDSRLAYYETTLNLTLDYRMHEKLWVPDCYFLNSKDAFVHDVTVENRVFQLHPDGTVR 167
Query: 453 WIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHTSDEM 569
+ RL + S+ L +P D Q C S +T +++
Sbjct: 168 YGIRLTTTAACSLDLHKFPMDKQACNLVVESYGYTVEDI 206
>BC033801-1|AAH33801.1| 452|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, delta protein.
Length = 452
Score = 48.0 bits (109), Expect = 5e-05
Identities = 40/151 (26%), Positives = 69/151 (45%), Gaps = 9/151 (5%)
Frame = +3
Query: 144 IDSLLATYDRDSPPD-SKIVVNLTLHLRHANI---RESESTVRIQADLQMNWIDKRLSWN 311
+D L+A Y R+ P VN+ L L A+I E+ + L +W D RLS+N
Sbjct: 44 LDGLIAGYARNFRPGIGGPPVNVALALEVASIDHISEANMEYTMTVFLHQSWRDSRLSYN 103
Query: 312 AGG--VGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDIS 476
+G + V ++LW PD ++NA + D + R+ +G + + R+ +
Sbjct: 104 HTNETLGLDSRFV--DKLWLPDTFIVNAKSAWFHDVTVENKLIRLQPDGVILYSIRITST 161
Query: 477 TPISMQLDNWPNDMQTCTFKFGSRMHTSDEM 569
M L +P D Q C S ++S+++
Sbjct: 162 VACDMDLAKYPMDEQECMLDLESYGYSSEDI 192
>AL391845-4|CAI15436.1| 452|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, delta protein.
Length = 452
Score = 48.0 bits (109), Expect = 5e-05
Identities = 40/151 (26%), Positives = 69/151 (45%), Gaps = 9/151 (5%)
Frame = +3
Query: 144 IDSLLATYDRDSPPD-SKIVVNLTLHLRHANI---RESESTVRIQADLQMNWIDKRLSWN 311
+D L+A Y R+ P VN+ L L A+I E+ + L +W D RLS+N
Sbjct: 44 LDGLIAGYARNFRPGIGGPPVNVALALEVASIDHISEANMEYTMTVFLHQSWRDSRLSYN 103
Query: 312 AGG--VGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDIS 476
+G + V ++LW PD ++NA + D + R+ +G + + R+ +
Sbjct: 104 HTNETLGLDSRFV--DKLWLPDTFIVNAKSAWFHDVTVENKLIRLQPDGVILYSIRITST 161
Query: 477 TPISMQLDNWPNDMQTCTFKFGSRMHTSDEM 569
M L +P D Q C S ++S+++
Sbjct: 162 VACDMDLAKYPMDEQECMLDLESYGYSSEDI 192
>AF016917-1|AAB70007.1| 452|Homo sapiens GABA-A receptor delta
subunit protein.
Length = 452
Score = 48.0 bits (109), Expect = 5e-05
Identities = 40/151 (26%), Positives = 69/151 (45%), Gaps = 9/151 (5%)
Frame = +3
Query: 144 IDSLLATYDRDSPPD-SKIVVNLTLHLRHANI---RESESTVRIQADLQMNWIDKRLSWN 311
+D L+A Y R+ P VN+ L L A+I E+ + L +W D RLS+N
Sbjct: 44 LDGLIAGYARNFRPGIGGPPVNVALALEVASIDHISEANMEYTMTVFLHQSWRDSRLSYN 103
Query: 312 AGG--VGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDIS 476
+G + V ++LW PD ++NA + D + R+ +G + + R+ +
Sbjct: 104 HTNETLGLDSRFV--DKLWLPDTFIVNAKSAWFHDVTVENKLIRLQPDGVILYSIRITST 161
Query: 477 TPISMQLDNWPNDMQTCTFKFGSRMHTSDEM 569
M L +P D Q C S ++S+++
Sbjct: 162 VACDMDLAKYPMDEQECMLDLESYGYSSEDI 192
>Z93848-1|CAI41994.1| 376|Homo sapiens glycine receptor, alpha 4
protein.
Length = 376
Score = 46.4 bits (105), Expect = 1e-04
Identities = 33/137 (24%), Positives = 61/137 (44%), Gaps = 6/137 (4%)
Frame = +3
Query: 183 PDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWNA---GGVGCSTWLVSSE 353
P + N+ ++ ++I ++ R+ L+ W D RLS+ + ++ S
Sbjct: 28 PPVNVTCNIFIN-SFSSITKTTMDYRVNVFLRQQWNDPRLSYREYPDDSLDLDPSMLDS- 85
Query: 354 RLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQT 524
+W+PD+ N + R+ NG+V + RL + M L N+P D+QT
Sbjct: 86 -IWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLILSCLMDLKNFPMDIQT 144
Query: 525 CTFKFGSRMHTSDEMDF 575
CT + S +T ++ F
Sbjct: 145 CTMQLESFGYTMKDLVF 161
>U93917-1|AAC39917.1| 449|Homo sapiens glycine receptor alpha 3
subunit protein.
Length = 449
Score = 46.4 bits (105), Expect = 1e-04
Identities = 32/137 (23%), Positives = 62/137 (45%), Gaps = 6/137 (4%)
Frame = +3
Query: 183 PDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWNA---GGVGCSTWLVSSE 353
P + N+ ++ +I E+ R+ L+ W D RL+++ + ++ S
Sbjct: 68 PPVNVTCNIFIN-SFGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPDDSLDLDPSMLDS- 125
Query: 354 RLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQT 524
+W+PD+ N + R+ NG+V + RL ++ M L N+P D+QT
Sbjct: 126 -IWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFPMDVQT 184
Query: 525 CTFKFGSRMHTSDEMDF 575
C + S +T +++ F
Sbjct: 185 CIMQLESFGYTMNDLIF 201
>BC036086-1|AAH36086.1| 464|Homo sapiens glycine receptor, alpha 3
protein.
Length = 464
Score = 46.4 bits (105), Expect = 1e-04
Identities = 32/137 (23%), Positives = 62/137 (45%), Gaps = 6/137 (4%)
Frame = +3
Query: 183 PDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWNA---GGVGCSTWLVSSE 353
P + N+ ++ +I E+ R+ L+ W D RL+++ + ++ S
Sbjct: 68 PPVNVTCNIFIN-SFGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPDDSLDLDPSMLDS- 125
Query: 354 RLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQT 524
+W+PD+ N + R+ NG+V + RL ++ M L N+P D+QT
Sbjct: 126 -IWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFPMDVQT 184
Query: 525 CTFKFGSRMHTSDEMDF 575
C + S +T +++ F
Sbjct: 185 CIMQLESFGYTMNDLIF 201
>AL049610-1|CAI42158.1| 376|Homo sapiens glycine receptor, alpha 4
protein.
Length = 376
Score = 46.4 bits (105), Expect = 1e-04
Identities = 33/137 (24%), Positives = 61/137 (44%), Gaps = 6/137 (4%)
Frame = +3
Query: 183 PDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWNA---GGVGCSTWLVSSE 353
P + N+ ++ ++I ++ R+ L+ W D RLS+ + ++ S
Sbjct: 28 PPVNVTCNIFIN-SFSSITKTTMDYRVNVFLRQQWNDPRLSYREYPDDSLDLDPSMLDS- 85
Query: 354 RLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQT 524
+W+PD+ N + R+ NG+V + RL + M L N+P D+QT
Sbjct: 86 -IWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLILSCLMDLKNFPMDIQT 144
Query: 525 CTFKFGSRMHTSDEMDF 575
CT + S +T ++ F
Sbjct: 145 CTMQLESFGYTMKDLVF 161
>AF017724-1|AAC39919.1| 465|Homo sapiens glycine receptor alpha 3
subunit protein.
Length = 465
Score = 46.4 bits (105), Expect = 1e-04
Identities = 32/137 (23%), Positives = 62/137 (45%), Gaps = 6/137 (4%)
Frame = +3
Query: 183 PDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWNA---GGVGCSTWLVSSE 353
P + N+ ++ +I E+ R+ L+ W D RL+++ + ++ S
Sbjct: 68 PPVNVTCNIFIN-SFGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPDDSLDLDPSMLDS- 125
Query: 354 RLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQT 524
+W+PD+ N + R+ NG+V + RL ++ M L N+P D+QT
Sbjct: 126 -IWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFPMDVQT 184
Query: 525 CTFKFGSRMHTSDEMDF 575
C + S +T +++ F
Sbjct: 185 CIMQLESFGYTMNDLIF 201
>BC114967-1|AAI14968.1| 366|Homo sapiens GLRA1 protein protein.
Length = 366
Score = 46.0 bits (104), Expect = 2e-04
Identities = 29/112 (25%), Positives = 53/112 (47%), Gaps = 6/112 (5%)
Frame = +3
Query: 258 RIQADLQMNWIDKRLSWNA---GGVGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR-- 422
R+ L+ W D RL++N + ++ S +W+PD+ N +
Sbjct: 4 RVNIFLRQQWNDPRLAYNEYPDDSLDLDPSMLDS--IWKPDLFFANEKGAHFHEITTDNK 61
Query: 423 -ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHTSDEMDF 575
R+S NG+V + R+ ++ M L N+P D+QTC + S +T +++ F
Sbjct: 62 LLRISRNGNVLYSIRITLTLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIF 113
>U95367-1|AAC51357.1| 440|Homo sapiens GABA-A receptor pi subunit
protein.
Length = 440
Score = 45.6 bits (103), Expect = 3e-04
Identities = 39/163 (23%), Positives = 75/163 (46%), Gaps = 8/163 (4%)
Frame = +3
Query: 111 ECENATSLSLM-IDSLLATYDRDSPPD---SKIVVNLTLHLRH-ANIRESESTVRIQADL 275
E + LSL ++L A Y++ P+ + + LTL + ++I ES L
Sbjct: 29 EVGRSDKLSLPGFENLTAGYNKFLRPNFGGEPVQIALTLDIASISSISESNMDYTATIYL 88
Query: 276 QMNWIDKRLSWNAGGVGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGS 446
+ W+D+RL + G + E LW PD ++ + + + + R+ +NG+
Sbjct: 89 RQRWMDQRLVFE-GNKSFTLDARLVEFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNGT 147
Query: 447 VSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHTSDEMDF 575
V + R+ + +M L +P D QTC + S + ++++F
Sbjct: 148 VLYALRITTTVACNMDLSKYPMDTQTCKLQLESWGYDGNDVEF 190
>BC109106-1|AAI09107.1| 440|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, pi protein.
Length = 440
Score = 45.6 bits (103), Expect = 3e-04
Identities = 39/163 (23%), Positives = 75/163 (46%), Gaps = 8/163 (4%)
Frame = +3
Query: 111 ECENATSLSLM-IDSLLATYDRDSPPD---SKIVVNLTLHLRH-ANIRESESTVRIQADL 275
E + LSL ++L A Y++ P+ + + LTL + ++I ES L
Sbjct: 29 EVGRSDKLSLPGFENLTAGYNKFLRPNFGGEPVQIALTLDIASISSISESNMDYTATIYL 88
Query: 276 QMNWIDKRLSWNAGGVGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGS 446
+ W+D+RL + G + E LW PD ++ + + + + R+ +NG+
Sbjct: 89 RQRWMDQRLVFE-GNKSFTLDARLVEFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNGT 147
Query: 447 VSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHTSDEMDF 575
V + R+ + +M L +P D QTC + S + ++++F
Sbjct: 148 VLYALRITTTVACNMDLSKYPMDTQTCKLQLESWGYDGNDVEF 190
>BC109105-1|AAI09106.1| 440|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, pi protein.
Length = 440
Score = 45.6 bits (103), Expect = 3e-04
Identities = 39/163 (23%), Positives = 75/163 (46%), Gaps = 8/163 (4%)
Frame = +3
Query: 111 ECENATSLSLM-IDSLLATYDRDSPPD---SKIVVNLTLHLRH-ANIRESESTVRIQADL 275
E + LSL ++L A Y++ P+ + + LTL + ++I ES L
Sbjct: 29 EVGRSDKLSLPGFENLTAGYNKFLRPNFGGEPVQIALTLDIASISSISESNMDYTATIYL 88
Query: 276 QMNWIDKRLSWNAGGVGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGS 446
+ W+D+RL + G + E LW PD ++ + + + + R+ +NG+
Sbjct: 89 RQRWMDQRLVFE-GNKSFTLDARLVEFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNGT 147
Query: 447 VSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHTSDEMDF 575
V + R+ + +M L +P D QTC + S + ++++F
Sbjct: 148 VLYALRITTTVACNMDLSKYPMDTQTCKLQLESWGYDGNDVEF 190
>BC096083-1|AAH96083.1| 198|Homo sapiens CHRNB4 protein protein.
Length = 198
Score = 45.6 bits (103), Expect = 3e-04
Identities = 30/115 (26%), Positives = 54/115 (46%), Gaps = 8/115 (6%)
Frame = +3
Query: 93 AIASAAECENATSLSLMIDSLL--ATYD---RDSPPDSKIV-VNLTLHLRHA-NIRESES 251
A+ C A + ++D LL Y+ R + S+++ + L L L ++ E E
Sbjct: 14 ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQ 73
Query: 252 TVRIQADLQMNWIDKRLSWNAGGV-GCSTWLVSSERLWRPDVVLLNAAATTAGDY 413
+ L+ W D RL+WN+ G + + ++R+W PD+VL N + T +
Sbjct: 74 IMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNKSLRTGSTW 128
>BC096081-1|AAH96081.1| 198|Homo sapiens CHRNB4 protein protein.
Length = 198
Score = 45.6 bits (103), Expect = 3e-04
Identities = 30/115 (26%), Positives = 54/115 (46%), Gaps = 8/115 (6%)
Frame = +3
Query: 93 AIASAAECENATSLSLMIDSLL--ATYD---RDSPPDSKIV-VNLTLHLRHA-NIRESES 251
A+ C A + ++D LL Y+ R + S+++ + L L L ++ E E
Sbjct: 14 ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQ 73
Query: 252 TVRIQADLQMNWIDKRLSWNAGGV-GCSTWLVSSERLWRPDVVLLNAAATTAGDY 413
+ L+ W D RL+WN+ G + + ++R+W PD+VL N + T +
Sbjct: 74 IMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNKSLRTGSTW 128
>BC074865-1|AAH74865.1| 440|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, pi protein.
Length = 440
Score = 45.6 bits (103), Expect = 3e-04
Identities = 39/163 (23%), Positives = 75/163 (46%), Gaps = 8/163 (4%)
Frame = +3
Query: 111 ECENATSLSLM-IDSLLATYDRDSPPD---SKIVVNLTLHLRH-ANIRESESTVRIQADL 275
E + LSL ++L A Y++ P+ + + LTL + ++I ES L
Sbjct: 29 EVGRSDKLSLPGFENLTAGYNKFLRPNFGGEPVQIALTLDIASISSISESNMDYTATIYL 88
Query: 276 QMNWIDKRLSWNAGGVGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGS 446
+ W+D+RL + G + E LW PD ++ + + + + R+ +NG+
Sbjct: 89 RQRWMDQRLVFE-GNKSFTLDARLVEFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNGT 147
Query: 447 VSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHTSDEMDF 575
V + R+ + +M L +P D QTC + S + ++++F
Sbjct: 148 VLYALRITTTVACNMDLSKYPMDTQTCKLQLESWGYDGNDVEF 190
>BC074810-1|AAH74810.1| 440|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, pi protein.
Length = 440
Score = 45.6 bits (103), Expect = 3e-04
Identities = 39/163 (23%), Positives = 75/163 (46%), Gaps = 8/163 (4%)
Frame = +3
Query: 111 ECENATSLSLM-IDSLLATYDRDSPPD---SKIVVNLTLHLRH-ANIRESESTVRIQADL 275
E + LSL ++L A Y++ P+ + + LTL + ++I ES L
Sbjct: 29 EVGRSDKLSLPGFENLTAGYNKFLRPNFGGEPVQIALTLDIASISSISESNMDYTATIYL 88
Query: 276 QMNWIDKRLSWNAGGVGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGS 446
+ W+D+RL + G + E LW PD ++ + + + + R+ +NG+
Sbjct: 89 RQRWMDQRLVFE-GNKSFTLDARLVEFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNGT 147
Query: 447 VSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHTSDEMDF 575
V + R+ + +M L +P D QTC + S + ++++F
Sbjct: 148 VLYALRITTTVACNMDLSKYPMDTQTCKLQLESWGYDGNDVEF 190
>AF009702-1|AAC24194.1| 440|Homo sapiens GABA-A receptor pi subunit
protein.
Length = 440
Score = 45.6 bits (103), Expect = 3e-04
Identities = 39/163 (23%), Positives = 75/163 (46%), Gaps = 8/163 (4%)
Frame = +3
Query: 111 ECENATSLSLM-IDSLLATYDRDSPPD---SKIVVNLTLHLRH-ANIRESESTVRIQADL 275
E + LSL ++L A Y++ P+ + + LTL + ++I ES L
Sbjct: 29 EVGRSDKLSLPGFENLTAGYNKFLRPNFGGEPVQIALTLDIASISSISESNMDYTATIYL 88
Query: 276 QMNWIDKRLSWNAGGVGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGS 446
+ W+D+RL + G + E LW PD ++ + + + + R+ +NG+
Sbjct: 89 RQRWMDQRLVFE-GNKSFTLDARLVEFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNGT 147
Query: 447 VSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHTSDEMDF 575
V + R+ + +M L +P D QTC + S + ++++F
Sbjct: 148 VLYALRITTTVACNMDLSKYPMDTQTCKLQLESWGYDGNDVEF 190
>BC031087-1|AAH31087.1| 465|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, gamma 1 protein.
Length = 465
Score = 44.8 bits (101), Expect = 5e-04
Identities = 35/155 (22%), Positives = 65/155 (41%), Gaps = 7/155 (4%)
Frame = +3
Query: 132 LSLMIDSLLATYDRDSPPDSKI---VVNLTLHLRHAN-IRESESTVRIQADLQMNWIDKR 299
++ +++SLL YD PD + V+ +++ + I W D R
Sbjct: 64 ITQILNSLLQGYDNKLRPDIGVRPTVIETDVYVNSIGPVDPINMEYTIDIIFAQTWFDSR 123
Query: 300 LSWNAGGVGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLD 470
L +N+ ++W PD N+ + A R+ N+G V + RL
Sbjct: 124 LKFNSTMKVLMLNSNMVGKIWIPDTFFRNSRKSDAHWITTPNRLLRIWNDGRVLYTLRLT 183
Query: 471 ISTPISMQLDNWPNDMQTCTFKFGSRMHTSDEMDF 575
I+ +QL N+P D +C +F S + +E+++
Sbjct: 184 INAECYLQLHNFPMDEHSCPLEFSSYGYPKNEIEY 218
>BC074795-1|AAH74795.1| 467|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, gamma 2 protein.
Length = 467
Score = 44.4 bits (100), Expect = 6e-04
Identities = 35/170 (20%), Positives = 71/170 (41%), Gaps = 7/170 (4%)
Frame = +3
Query: 132 LSLMIDSLLATYDRDSPPDSKIVVNLTLHLRHANIRESESTVRIQADLQM----NWIDKR 299
+++++++LL YD PD + L + N + + ++ + + W D+R
Sbjct: 66 VTVILNNLLEGYDNKLRPDIGVKPTLIHTDMYVNSIGPVNAINMEYTIDIFFAQTWYDRR 125
Query: 300 LSWNAGGVGCSTWLVSSERLWRPDVVLLNAAATTAGDYAL---RARVSNNGSVSWIKRLD 470
L +N+ ++W PD N+ A R+ N+G V + RL
Sbjct: 126 LKFNSTIKVLRLNSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYTLRLT 185
Query: 471 ISTPISMQLDNWPNDMQTCTFKFGSRMHTSDEMDFVIDKRIYSMFESGPW 620
I +QL N+P D +C +F S + +E+ + + + ++ W
Sbjct: 186 IDAECQLQLHNFPMDEHSCPLEFSSYGYPREEIVYQWKRSSVEVGDTRSW 235
>BC069348-1|AAH69348.1| 467|Homo sapiens gamma-aminobutyric acid A
receptor, gamma 2, isoform 2 precursor protein.
Length = 467
Score = 44.4 bits (100), Expect = 6e-04
Identities = 35/170 (20%), Positives = 71/170 (41%), Gaps = 7/170 (4%)
Frame = +3
Query: 132 LSLMIDSLLATYDRDSPPDSKIVVNLTLHLRHANIRESESTVRIQADLQM----NWIDKR 299
+++++++LL YD PD + L + N + + ++ + + W D+R
Sbjct: 66 VTVILNNLLEGYDNKLRPDIGVKPTLIHTDMYVNSIGPVNAINMEYTIDIFFAQTWYDRR 125
Query: 300 LSWNAGGVGCSTWLVSSERLWRPDVVLLNAAATTAGDYAL---RARVSNNGSVSWIKRLD 470
L +N+ ++W PD N+ A R+ N+G V + RL
Sbjct: 126 LKFNSTIKVLRLNSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYTLRLT 185
Query: 471 ISTPISMQLDNWPNDMQTCTFKFGSRMHTSDEMDFVIDKRIYSMFESGPW 620
I +QL N+P D +C +F S + +E+ + + + ++ W
Sbjct: 186 IDAECQLQLHNFPMDEHSCPLEFSSYGYPREEIVYQWKRSSVEVGDTRSW 235
>BC059389-1|AAH59389.1| 475|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, gamma 2 protein.
Length = 475
Score = 44.4 bits (100), Expect = 6e-04
Identities = 35/170 (20%), Positives = 71/170 (41%), Gaps = 7/170 (4%)
Frame = +3
Query: 132 LSLMIDSLLATYDRDSPPDSKIVVNLTLHLRHANIRESESTVRIQADLQM----NWIDKR 299
+++++++LL YD PD + L + N + + ++ + + W D+R
Sbjct: 66 VTVILNNLLEGYDNKLRPDIGVKPTLIHTDMYVNSIGPVNAINMEYTIDIFFAQTWYDRR 125
Query: 300 LSWNAGGVGCSTWLVSSERLWRPDVVLLNAAATTAGDYAL---RARVSNNGSVSWIKRLD 470
L +N+ ++W PD N+ A R+ N+G V + RL
Sbjct: 126 LKFNSTIKVLRLNSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYTLRLT 185
Query: 471 ISTPISMQLDNWPNDMQTCTFKFGSRMHTSDEMDFVIDKRIYSMFESGPW 620
I +QL N+P D +C +F S + +E+ + + + ++ W
Sbjct: 186 IDAECQLQLHNFPMDEHSCPLEFSSYGYPREEIVYQWKRSSVEVGDTRSW 235
>AF165124-1|AAD50273.1| 467|Homo sapiens gamma-aminobutyric acid A
receptor gamma 2 protein.
Length = 467
Score = 44.4 bits (100), Expect = 6e-04
Identities = 35/170 (20%), Positives = 71/170 (41%), Gaps = 7/170 (4%)
Frame = +3
Query: 132 LSLMIDSLLATYDRDSPPDSKIVVNLTLHLRHANIRESESTVRIQADLQM----NWIDKR 299
+++++++LL YD PD + L + N + + ++ + + W D+R
Sbjct: 66 VTVILNNLLEGYDNKLRPDIGVKPTLIHTDMYVNSIGPVNAINMEYTIDIFFAQTWYDRR 125
Query: 300 LSWNAGGVGCSTWLVSSERLWRPDVVLLNAAATTAGDYAL---RARVSNNGSVSWIKRLD 470
L +N+ ++W PD N+ A R+ N+G V + RL
Sbjct: 126 LKFNSTIKVLRLNSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYTLRLT 185
Query: 471 ISTPISMQLDNWPNDMQTCTFKFGSRMHTSDEMDFVIDKRIYSMFESGPW 620
I +QL N+P D +C +F S + +E+ + + + ++ W
Sbjct: 186 IDAECQLQLHNFPMDEHSCPLEFSSYGYPREEIVYQWKRSSVEVGDTRSW 235
>X15376-1|CAA33437.1| 467|Homo sapiens GABA-A receptor gamma 2
subunit protein.
Length = 467
Score = 43.2 bits (97), Expect = 0.001
Identities = 35/170 (20%), Positives = 71/170 (41%), Gaps = 7/170 (4%)
Frame = +3
Query: 132 LSLMIDSLLATYDRDSPPDSKIVVNLTLHLRHANIRESESTVRIQADLQM----NWIDKR 299
+++++++LL YD PD + L + N + + ++ + + W D+R
Sbjct: 66 VTVILNNLLEGYDNKLRPDIGVKPTLIHTDMYVNSIGPVNAINMEYTIDIFFAQMWYDRR 125
Query: 300 LSWNAGGVGCSTWLVSSERLWRPDVVLLNAAATTAGDYAL---RARVSNNGSVSWIKRLD 470
L +N+ ++W PD N+ A R+ N+G V + RL
Sbjct: 126 LKFNSTIKVLRLNSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYSLRLT 185
Query: 471 ISTPISMQLDNWPNDMQTCTFKFGSRMHTSDEMDFVIDKRIYSMFESGPW 620
I +QL N+P D +C +F S + +E+ + + + ++ W
Sbjct: 186 IDAECQLQLHNFPMDEHSCPLEFSSYGYPREEIVYQWKRSSVEVGDTRSW 235
>AM293589-1|CAL25321.1| 430|Homo sapiens 5-hydroxytryptamine
receptor 3 subunit B protein.
Length = 430
Score = 42.7 bits (96), Expect = 0.002
Identities = 22/97 (22%), Positives = 47/97 (48%), Gaps = 1/97 (1%)
Frame = +3
Query: 285 WIDKRLSWNAGGVGCSTWL-VSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVSWIK 461
W D+ LSWN+ + + +W PD+++ V+++G++ K
Sbjct: 77 WNDEFLSWNSSMFDEIREISLPLSAIWAPDIIINEFVDIERSPDLPYVYVNSSGTIENYK 136
Query: 462 RLDISTPISMQLDNWPNDMQTCTFKFGSRMHTSDEMD 572
+ + + S++ +P D+Q C+ F S +HT +++D
Sbjct: 137 PIQVVSACSLETYAFPFDVQNCSLTFKSILHTVEDVD 173
>AF169255-1|AAF03691.1| 441|Homo sapiens 5-hydroxytryptamine 3
receptor B subunit protein.
Length = 441
Score = 41.5 bits (93), Expect = 0.004
Identities = 22/97 (22%), Positives = 47/97 (48%), Gaps = 1/97 (1%)
Frame = +3
Query: 285 WIDKRLSWNAGGVGCSTWL-VSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVSWIK 461
W D+ LSWN+ + + +W PD+++ V+++G++ K
Sbjct: 88 WNDEFLSWNSSMFDEIREISLPLSAIWAPDIIINEFVDIERYPDLPYVYVNSSGTIENYK 147
Query: 462 RLDISTPISMQLDNWPNDMQTCTFKFGSRMHTSDEMD 572
+ + + S++ +P D+Q C+ F S +HT +++D
Sbjct: 148 PIQVVSACSLETYAFPFDVQNCSLTFKSILHTVEDVD 184
>AF080582-1|AAD12242.1| 441|Homo sapiens 5-hydroxytryptamine 3
receptor B subunit precursor protein.
Length = 441
Score = 41.5 bits (93), Expect = 0.004
Identities = 22/97 (22%), Positives = 47/97 (48%), Gaps = 1/97 (1%)
Frame = +3
Query: 285 WIDKRLSWNAGGVGCSTWL-VSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVSWIK 461
W D+ LSWN+ + + +W PD+++ V+++G++ K
Sbjct: 88 WNDEFLSWNSSMFDEIREISLPLSAIWAPDIIINEFVDIERYPDLPYVYVNSSGTIENYK 147
Query: 462 RLDISTPISMQLDNWPNDMQTCTFKFGSRMHTSDEMD 572
+ + + S++ +P D+Q C+ F S +HT +++D
Sbjct: 148 PIQVVSACSLETYAFPFDVQNCSLTFKSILHTVEDVD 184
>AB209359-1|BAD92596.1| 533|Homo sapiens cholinergic receptor,
nicotinic, alpha polypeptide 4 precursor variant
protein.
Length = 533
Score = 40.7 bits (91), Expect = 0.007
Identities = 25/91 (27%), Positives = 41/91 (45%), Gaps = 3/91 (3%)
Frame = +3
Query: 357 LWRPDVVLLNAAATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFK 536
LW +A A + +A + ++G V W + S+ + +P D Q CT K
Sbjct: 25 LWLCCCTFTSADGDFAVTHLTKAHLFHDGRVQWTPPAIYKSSCSIDVTFFPFDQQNCTMK 84
Query: 537 FGSRMHTSDEMDFV-IDKRI--YSMFESGPW 620
FGS + ++D V + R+ +ESG W
Sbjct: 85 FGSWTYDKAKIDLVNMHSRVDQLDFWESGEW 115
>BC096291-1|AAH96291.1| 556|Homo sapiens CHRNA4 protein protein.
Length = 556
Score = 39.9 bits (89), Expect = 0.013
Identities = 24/79 (30%), Positives = 40/79 (50%), Gaps = 7/79 (8%)
Frame = +3
Query: 405 GDYAL----RARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHTSDEMD 572
GD+A+ +A + ++G V W + S+ + +P D Q CT KFGS + ++D
Sbjct: 60 GDFAVTHLTKAHLFHDGRVQWTPPAIYKSSCSIDVTFFPFDQQNCTMKFGSWTYDKAKID 119
Query: 573 FV-IDKRI--YSMFESGPW 620
V + R+ +ESG W
Sbjct: 120 LVNMHSRVDQLDFWESGEW 138
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 121,599,238
Number of Sequences: 237096
Number of extensions: 2659182
Number of successful extensions: 6853
Number of sequences better than 10.0: 187
Number of HSP's better than 10.0 without gapping: 5975
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 6683
length of database: 76,859,062
effective HSP length: 90
effective length of database: 55,520,422
effective search space used: 12103451996
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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