Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BmNP03_FL5_L02
(846 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
AJ306454-1|CAC34819.1| 497|Homo sapiens neuronal nicotinic acet... 54 9e-07
Y08416-1|CAA69693.1| 498|Homo sapiens nicotinic acetylcholine r... 52 3e-06
U62439-1|AAB40117.1| 498|Homo sapiens nicotinic acetylcholine r... 52 3e-06
U48861-1|AAA92123.1| 498|Homo sapiens beta 4 nicotinic acetylch... 52 3e-06
BC096082-1|AAH96082.1| 498|Homo sapiens cholinergic receptor, n... 52 3e-06
BC096080-1|AAH96080.1| 498|Homo sapiens cholinergic receptor, n... 52 3e-06
AF306329-1|AAL02062.1| 498|Homo sapiens neuronal nicotinic acet... 52 3e-06
Y00762-1|CAA68731.1| 457|Homo sapiens protein ( Human mRNA for ... 51 5e-06
X02502-1|CAA26344.1| 457|Homo sapiens acetylcholine receptor pr... 51 5e-06
S77094-1|AAD14247.1| 457|Homo sapiens nicotinic acetylcholine r... 51 5e-06
BC006314-1|AAH06314.1| 269|Homo sapiens CHRNA1 protein protein. 51 5e-06
AC018890-1|AAY14687.1| 457|Homo sapiens unknown protein. 51 5e-06
BC111802-1|AAI11803.1| 465|Homo sapiens CHRNG protein protein. 49 2e-05
X68275-1|CAA48336.1| 451|Homo sapiens nicotinic receptor beta 4... 47 7e-05
BC096083-1|AAH96083.1| 198|Homo sapiens CHRNB4 protein protein. 47 1e-04
BC096081-1|AAH96081.1| 198|Homo sapiens CHRNB4 protein protein. 47 1e-04
Y08417-1|CAA69694.1| 458|Homo sapiens nicotinic acetylcholine r... 46 2e-04
X67513-1|CAA47851.1| 423|Homo sapiens nicotinic acetylcholine ... 46 2e-04
X14830-1|CAA32939.1| 501|Homo sapiens protein ( Human mRNA for ... 46 2e-04
U62438-1|AAB40116.1| 458|Homo sapiens nicotinic acetylcholine r... 46 2e-04
BC110597-1|AAI10598.1| 411|Homo sapiens ligand-gated ion channe... 46 2e-04
BC069788-1|AAH69788.1| 458|Homo sapiens cholinergic receptor, n... 46 2e-04
BC069703-1|AAH69703.1| 458|Homo sapiens cholinergic receptor, n... 46 2e-04
BC069681-1|AAH69681.1| 458|Homo sapiens cholinergic receptor, n... 46 2e-04
BC023553-1|AAH23553.1| 501|Homo sapiens cholinergic receptor, n... 46 2e-04
BC011371-1|AAH11371.1| 501|Homo sapiens cholinergic receptor, n... 46 2e-04
AK122638-1|BAC85499.1| 266|Homo sapiens yte protein of 76kDa) (... 46 2e-04
AF512521-1|AAO20969.1| 411|Homo sapiens ligand-gated ion channe... 46 2e-04
AF140765-1|AAD33063.1| 458|Homo sapiens neuronal acetylcholine ... 46 2e-04
X01715-1|CAA25861.1| 520|Homo sapiens acetylcholine receptor ga... 45 3e-04
BT006897-1|AAP35543.1| 505|Homo sapiens cholinergic receptor, n... 45 3e-04
BT006646-1|AAP35292.1| 489|Homo sapiens cholinergic receptor, n... 45 3e-04
BC113575-1|AAI13576.1| 479|Homo sapiens cholinergic receptor, n... 45 3e-04
BC113549-1|AAI13550.1| 479|Homo sapiens cholinergic receptor, n... 45 3e-04
BC006114-1|AAH06114.1| 489|Homo sapiens CHRNA3 protein protein. 45 3e-04
BC002996-1|AAH02996.1| 505|Homo sapiens cholinergic receptor, n... 45 3e-04
BC001642-1|AAH01642.1| 505|Homo sapiens cholinergic receptor, n... 45 3e-04
BC000513-1|AAH00513.1| 505|Homo sapiens cholinergic receptor, n... 45 3e-04
AY123244-1|AAM74523.1| 479|Homo sapiens nicotinic acetylcholine... 45 3e-04
AJ243342-1|CAB65091.1| 479|Homo sapiens nicotinic acetylcholine... 45 3e-04
AF385584-1|AAK68110.1| 489|Homo sapiens nicotinic cholinergic r... 45 3e-04
AF227732-1|AAF61920.1| 470|Homo sapiens nicotinic acetylcholine... 45 3e-04
AC118275-1|AAY40986.1| 479|Homo sapiens unknown protein. 45 3e-04
AC092165-3|AAY24103.1| 520|Homo sapiens unknown protein. 45 3e-04
AB223030-1|BAE19924.1| 411|Homo sapiens ligand-gated ion-channe... 45 3e-04
Y08418-1|CAA69695.1| 503|Homo sapiens nicotinic acetylcholine r... 44 5e-04
U62432-1|AAB40110.1| 504|Homo sapiens nicotinic acetylcholine r... 44 5e-04
M37981-1|AAA59942.1| 503|Homo sapiens neuronal nicotinic acetyl... 44 5e-04
BC098443-1|AAH98443.1| 504|Homo sapiens cholinergic receptor, n... 44 5e-04
AJ007783-1|CAA07682.1| 504|Homo sapiens nicotinic acetylcholine... 44 5e-04
Y16281-1|CAA76154.1| 529|Homo sapiens nicotinic acetylcholine r... 44 0.001
X53559-1|CAA37625.1| 474|Homo sapiens neuronal nicotinic acetyl... 44 0.001
U62431-1|AAB40109.1| 529|Homo sapiens nicotinic acetylcholine r... 44 0.001
U77731-2|AAB38273.1| 360|Homo sapiens glycine receptor alpha 2B... 43 0.001
S77554-1|AAB33983.1| 474|Homo sapiens GABAA receptor beta 2 sub... 43 0.001
S77553-1|AAB33982.1| 512|Homo sapiens GABAA receptor beta 2 sub... 43 0.001
S67368-1|AAB29370.1| 474|Homo sapiens gamma-aminobutyric acid A... 43 0.001
DQ644022-1|ABG35128.1| 456|Homo sapiens 5-HT3 receptor subunit ... 43 0.001
CR450343-1|CAG29339.1| 452|Homo sapiens GLRA2 protein. 43 0.001
BC105639-1|AAI05640.1| 474|Homo sapiens GABRB2 protein protein. 43 0.001
BC099719-1|AAH99719.1| 474|Homo sapiens GABRB2 protein protein. 43 0.001
BC099705-1|AAH99705.1| 474|Homo sapiens GABRB2 protein protein. 43 0.001
AY437084-1|AAR87843.1| 452|Homo sapiens glycine receptor alpha2... 43 0.001
Y08419-1|CAA69696.1| 468|Homo sapiens nicotinic acetylcholine r... 43 0.002
X52008-1|CAA36257.1| 452|Homo sapiens inhibitory glycine recept... 43 0.002
U77731-1|AAB38272.1| 360|Homo sapiens glycine receptor alpha 2 ... 43 0.002
U62434-1|AAB40112.1| 468|Homo sapiens nicotinic acetylcholine r... 43 0.002
M59216-1|AAA35862.1| 474|Homo sapiens gamma-aminobutyric acid r... 43 0.002
BC101185-1|AAI01186.1| 374|Homo sapiens HTR3E protein protein. 43 0.002
BC101183-1|AAI01184.1| 471|Homo sapiens 5-hydroxytryptamine (se... 43 0.002
BC101182-1|AAI01183.1| 471|Homo sapiens 5-hydroxytryptamine (se... 43 0.002
BC033639-1|AAH33639.1| 468|Homo sapiens cholinergic receptor, n... 43 0.002
BC032864-1|AAH32864.1| 452|Homo sapiens glycine receptor, alpha... 43 0.002
AY437083-1|AAR87842.1| 452|Homo sapiens glycine receptor alpha2... 43 0.002
AY159813-1|AAO38167.2| 471|Homo sapiens 5-hydroxytryptamine ser... 43 0.002
AJ306481-1|CAC34820.1| 468|Homo sapiens neuronal nicotinic acet... 43 0.002
AF053495-1|AAC35290.1| 452|Homo sapiens glycine receptor alpha ... 43 0.002
X14767-1|CAA32875.1| 474|Homo sapiens GABA-A receptor beta 1 su... 42 0.003
M86383-1|AAC84176.1| 502|Homo sapiens nicotinic acetylcholine r... 42 0.003
Z23141-1|CAA80672.1| 479|Homo sapiens cholinergic receptor, nic... 42 0.004
Y16282-1|CAA76155.1| 494|Homo sapiens nicotinic acetylcholine r... 42 0.004
Y08420-1|CAA69697.1| 502|Homo sapiens nicotinic acetylcholine r... 42 0.004
X70297-1|CAA49778.1| 502|Homo sapiens neuronal nicotinic acetyl... 42 0.004
U62436-1|AAB40114.1| 502|Homo sapiens nicotinic acetylcholine r... 42 0.004
U62435-1|AAB40113.1| 494|Homo sapiens nicotinic acetylcholine r... 42 0.004
U40583-1|AAA83561.1| 502|Homo sapiens alpha 7 neuronal nicotini... 42 0.004
M83712-1|AAA58357.1| 468|Homo sapiens nicotinic receptor alpha ... 42 0.004
BC014456-1|AAH14456.1| 494|Homo sapiens cholinergic receptor, n... 42 0.004
AJ586911-1|CAE52911.1| 502|Homo sapiens nicotinic acetylcholine... 42 0.004
AF385585-1|AAK68111.1| 502|Homo sapiens nicotinic cholinergic r... 42 0.004
AB079251-1|BAC06855.1| 494|Homo sapiens Nicotinic acetylcholine... 42 0.004
Y08421-1|CAA69698.1| 627|Homo sapiens nicotinic acetylcholine r... 41 0.005
X89741-1|CAA61893.1| 627|Homo sapiens neuronal acetylcholine re... 41 0.005
X55019-1|CAA38759.1| 517|Homo sapiens acetylcholine receptor de... 41 0.005
U62433-1|AAB40111.1| 627|Homo sapiens nicotinic acetylcholine r... 41 0.005
L35901-1|AAA64743.1| 627|Homo sapiens nicotinic acetylcholine r... 41 0.005
DQ093071-1|AAY88737.1| 627|Homo sapiens cholinergic receptor, n... 41 0.005
BC131799-1|AAI31800.1| 447|Homo sapiens 5-hydroxytryptamine (se... 41 0.005
BC096290-1|AAH96290.1| 627|Homo sapiens cholinergic receptor, n... 41 0.005
BC093925-1|AAH93925.1| 517|Homo sapiens cholinergic receptor, n... 41 0.005
BC093923-1|AAH93923.1| 517|Homo sapiens cholinergic receptor, n... 41 0.005
AJ295237-1|CAC16144.1| 450|Homo sapiens neuronal nicotinic acet... 41 0.005
AJ278118-1|CAC20435.1| 450|Homo sapiens neuronal nicotinic acet... 41 0.005
AF327367-1|AAK14333.1| 450|Homo sapiens nicotinic acetylcholine... 41 0.005
AF199235-1|AAG00795.2| 450|Homo sapiens nicotinic acetylcholine... 41 0.005
AC092165-2|AAY24102.1| 517|Homo sapiens unknown protein. 41 0.005
X87629-1|CAA60959.1| 602|Homo sapiens nicotinic acetylcholine r... 41 0.006
BC109211-1|AAI09212.1| 632|Homo sapiens gamma-aminobutyric acid... 41 0.006
BC109210-1|AAI09211.1| 632|Homo sapiens gamma-aminobutyric acid... 41 0.006
AY349353-1|AAQ93477.1| 456|Homo sapiens 5-HT3c1 serotonin recep... 41 0.006
AY349352-1|AAQ93476.1| 441|Homo sapiens 5-HT3c1 serotonin recep... 41 0.006
AF459285-1|AAL66182.1| 447|Homo sapiens 5-hydroxytryptamine rec... 41 0.006
AF189259-1|AAF70380.1| 632|Homo sapiens GABA-A receptor theta s... 41 0.006
AF144648-1|AAD51172.1| 627|Homo sapiens GABA-A receptor theta p... 41 0.006
AJ001935-1|CAA05108.1| 504|Homo sapiens CHRNB2 protein. 40 0.009
Y08415-1|CAA69692.1| 502|Homo sapiens nicotinic acetylcholine r... 40 0.011
X53179-1|CAA37320.1| 502|Homo sapiens precursor peptide (AA -25... 40 0.011
U62437-1|AAB40115.1| 502|Homo sapiens nicotinic acetylcholine r... 40 0.011
BC075041-1|AAH75041.1| 502|Homo sapiens cholinergic receptor, n... 40 0.011
BC075040-1|AAH75040.1| 502|Homo sapiens cholinergic receptor, n... 40 0.011
AL592078-3|CAI16184.1| 502|Homo sapiens cholinergic receptor, n... 40 0.011
AF077186-1|AAD45422.1| 502|Homo sapiens neuronal nicotinic acet... 40 0.011
U93917-1|AAC39917.1| 449|Homo sapiens glycine receptor alpha 3 ... 39 0.020
BC114947-1|AAI14948.1| 457|Homo sapiens GLRA1 protein protein. 39 0.020
BC074980-1|AAH74980.1| 449|Homo sapiens glycine receptor, alpha... 39 0.020
BC036086-1|AAH36086.1| 464|Homo sapiens glycine receptor, alpha... 39 0.020
AF017724-1|AAC39919.1| 465|Homo sapiens glycine receptor alpha ... 39 0.020
X52009-1|CAA36258.1| 449|Homo sapiens inhibitory glycine recept... 39 0.026
Z93848-1|CAI41994.1| 376|Homo sapiens glycine receptor, alpha 4... 38 0.061
BC033801-1|AAH33801.1| 452|Homo sapiens gamma-aminobutyric acid... 38 0.061
BC022449-1|AAH22449.1| 474|Homo sapiens gamma-aminobutyric acid... 38 0.061
AL391845-4|CAI15436.1| 452|Homo sapiens gamma-aminobutyric acid... 38 0.061
AL049610-1|CAI42158.1| 376|Homo sapiens glycine receptor, alpha... 38 0.061
AF016917-1|AAB70007.1| 452|Homo sapiens GABA-A receptor delta s... 38 0.061
BC114967-1|AAI14968.1| 366|Homo sapiens GLRA1 protein protein. 36 0.24
>AJ306454-1|CAC34819.1| 497|Homo sapiens neuronal nicotinic
acetylcholine receptor beta-4 subunit protein.
Length = 497
Score = 53.6 bits (123), Expect = 9e-07
Identities = 42/166 (25%), Positives = 72/166 (43%), Gaps = 8/166 (4%)
Frame = +3
Query: 48 LLPFLLTCAIASAAECENATSLSLMIDSLL--ATYDRESPP--DSKIVVNLTLHLRHA-- 209
L+ F L A+ C A + ++D LL Y+ P S ++++ L L A
Sbjct: 7 LVLFFLV-ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQL 65
Query: 210 -NIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTA 383
++ E E + L+ W D RL+WN+ + G + + ++R+W PD+VL N T
Sbjct: 66 ISVNEREQIMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNDGTYE 125
Query: 384 GDYALRARVSNNXSVSXIKRLDISTPISMXLXNWPNDMXTCTFQVR 521
V +N SV + + + + +P D CT + R
Sbjct: 126 VSVYTNLIVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFR 171
>Y08416-1|CAA69693.1| 498|Homo sapiens nicotinic acetylcholine
receptor beta4 subunit precursor protein.
Length = 498
Score = 51.6 bits (118), Expect = 3e-06
Identities = 43/167 (25%), Positives = 73/167 (43%), Gaps = 9/167 (5%)
Frame = +3
Query: 48 LLPFLLTCAIASAAECENATSLSLMIDSLL--ATYDRESPP--DSKIVVNLTLHLRHA-- 209
L+ F L A+ C A + ++D LL Y+ P S ++++ L L A
Sbjct: 7 LVLFFLV-ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQL 65
Query: 210 -NIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLL-NAAATT 380
++ E E + L+ W D RL+WN+ + G + + ++R+W PD+VL NA T
Sbjct: 66 ISVNEREQIMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNADGTY 125
Query: 381 AGDYALRARVSNNXSVSXIKRLDISTPISMXLXNWPNDMXTCTFQVR 521
V +N SV + + + + +P D CT + R
Sbjct: 126 EVSVYTNLIVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFR 172
>U62439-1|AAB40117.1| 498|Homo sapiens nicotinic acetylcholine
receptor beta4 subunit precursor protein.
Length = 498
Score = 51.6 bits (118), Expect = 3e-06
Identities = 43/167 (25%), Positives = 73/167 (43%), Gaps = 9/167 (5%)
Frame = +3
Query: 48 LLPFLLTCAIASAAECENATSLSLMIDSLL--ATYDRESPP--DSKIVVNLTLHLRHA-- 209
L+ F L A+ C A + ++D LL Y+ P S ++++ L L A
Sbjct: 7 LVLFFLV-ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQL 65
Query: 210 -NIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLL-NAAATT 380
++ E E + L+ W D RL+WN+ + G + + ++R+W PD+VL NA T
Sbjct: 66 ISVNEREQIMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNADGTY 125
Query: 381 AGDYALRARVSNNXSVSXIKRLDISTPISMXLXNWPNDMXTCTFQVR 521
V +N SV + + + + +P D CT + R
Sbjct: 126 EVSVYTNLIVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFR 172
>U48861-1|AAA92123.1| 498|Homo sapiens beta 4 nicotinic
acetylcholine receptor subunit protein.
Length = 498
Score = 51.6 bits (118), Expect = 3e-06
Identities = 43/167 (25%), Positives = 73/167 (43%), Gaps = 9/167 (5%)
Frame = +3
Query: 48 LLPFLLTCAIASAAECENATSLSLMIDSLL--ATYDRESPP--DSKIVVNLTLHLRHA-- 209
L+ F L A+ C A + ++D LL Y+ P S ++++ L L A
Sbjct: 7 LVLFFLV-ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQL 65
Query: 210 -NIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLL-NAAATT 380
++ E E + L+ W D RL+WN+ + G + + ++R+W PD+VL NA T
Sbjct: 66 ISVNEREQIMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNADGTY 125
Query: 381 AGDYALRARVSNNXSVSXIKRLDISTPISMXLXNWPNDMXTCTFQVR 521
V +N SV + + + + +P D CT + R
Sbjct: 126 EVSVYTNLIVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFR 172
>BC096082-1|AAH96082.1| 498|Homo sapiens cholinergic receptor,
nicotinic, beta 4 protein.
Length = 498
Score = 51.6 bits (118), Expect = 3e-06
Identities = 43/167 (25%), Positives = 73/167 (43%), Gaps = 9/167 (5%)
Frame = +3
Query: 48 LLPFLLTCAIASAAECENATSLSLMIDSLL--ATYDRESPP--DSKIVVNLTLHLRHA-- 209
L+ F L A+ C A + ++D LL Y+ P S ++++ L L A
Sbjct: 7 LVLFFLV-ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQL 65
Query: 210 -NIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLL-NAAATT 380
++ E E + L+ W D RL+WN+ + G + + ++R+W PD+VL NA T
Sbjct: 66 ISVNEREQIMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNADGTY 125
Query: 381 AGDYALRARVSNNXSVSXIKRLDISTPISMXLXNWPNDMXTCTFQVR 521
V +N SV + + + + +P D CT + R
Sbjct: 126 EVSVYTNLIVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFR 172
>BC096080-1|AAH96080.1| 498|Homo sapiens cholinergic receptor,
nicotinic, beta 4 protein.
Length = 498
Score = 51.6 bits (118), Expect = 3e-06
Identities = 43/167 (25%), Positives = 73/167 (43%), Gaps = 9/167 (5%)
Frame = +3
Query: 48 LLPFLLTCAIASAAECENATSLSLMIDSLL--ATYDRESPP--DSKIVVNLTLHLRHA-- 209
L+ F L A+ C A + ++D LL Y+ P S ++++ L L A
Sbjct: 7 LVLFFLV-ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQL 65
Query: 210 -NIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLL-NAAATT 380
++ E E + L+ W D RL+WN+ + G + + ++R+W PD+VL NA T
Sbjct: 66 ISVNEREQIMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNADGTY 125
Query: 381 AGDYALRARVSNNXSVSXIKRLDISTPISMXLXNWPNDMXTCTFQVR 521
V +N SV + + + + +P D CT + R
Sbjct: 126 EVSVYTNLIVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFR 172
>AF306329-1|AAL02062.1| 498|Homo sapiens neuronal nicotinic
acetylcholine receptor beta 4 subunit protein.
Length = 498
Score = 51.6 bits (118), Expect = 3e-06
Identities = 43/167 (25%), Positives = 73/167 (43%), Gaps = 9/167 (5%)
Frame = +3
Query: 48 LLPFLLTCAIASAAECENATSLSLMIDSLL--ATYDRESPP--DSKIVVNLTLHLRHA-- 209
L+ F L A+ C A + ++D LL Y+ P S ++++ L L A
Sbjct: 7 LVLFFLV-ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQL 65
Query: 210 -NIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLL-NAAATT 380
++ E E + L+ W D RL+WN+ + G + + ++R+W PD+VL NA T
Sbjct: 66 ISVNEREQIMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNADGTY 125
Query: 381 AGDYALRARVSNNXSVSXIKRLDISTPISMXLXNWPNDMXTCTFQVR 521
V +N SV + + + + +P D CT + R
Sbjct: 126 EVSVYTNLIVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFR 172
>Y00762-1|CAA68731.1| 457|Homo sapiens protein ( Human mRNA for
muscle acetylcholine receptor alpha-subunit. ).
Length = 457
Score = 51.2 bits (117), Expect = 5e-06
Identities = 36/121 (29%), Positives = 58/121 (47%), Gaps = 6/121 (4%)
Frame = +3
Query: 54 PFLLTCAIASAAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHA---NIR 218
P LL ++ SA + + ++ L Y P D + VV +T+ L+ N+
Sbjct: 5 PLLLLFSLCSAGLVLGSEHETRLVAKLFKDYSSVVRPVEDHRQVVEVTVGLQLIQLINVD 64
Query: 219 ESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYA 395
E V L+ W+D L WN ++G + + SE++WRPD+VL N A GD+A
Sbjct: 65 EVNQIVTTNVRLKQQWVDYNLKWNPDDYGGVKKIHIPSEKIWRPDLVLYNNA---DGDFA 121
Query: 396 L 398
+
Sbjct: 122 I 122
>X02502-1|CAA26344.1| 457|Homo sapiens acetylcholine receptor
protein.
Length = 457
Score = 51.2 bits (117), Expect = 5e-06
Identities = 36/121 (29%), Positives = 58/121 (47%), Gaps = 6/121 (4%)
Frame = +3
Query: 54 PFLLTCAIASAAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHA---NIR 218
P LL ++ SA + + ++ L Y P D + VV +T+ L+ N+
Sbjct: 5 PLLLLFSLCSAGLVLGSEHETRLVAKLFKDYSSVVRPVEDHRQVVEVTVGLQLIQLINVD 64
Query: 219 ESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYA 395
E V L+ W+D L WN ++G + + SE++WRPD+VL N A GD+A
Sbjct: 65 EVNQIVTTNVRLKQQWVDYNLKWNPDDYGGVKKIHIPSEKIWRPDLVLYNNA---DGDFA 121
Query: 396 L 398
+
Sbjct: 122 I 122
>S77094-1|AAD14247.1| 457|Homo sapiens nicotinic acetylcholine
receptor alpha subunit|AChR protein.
Length = 457
Score = 51.2 bits (117), Expect = 5e-06
Identities = 36/121 (29%), Positives = 58/121 (47%), Gaps = 6/121 (4%)
Frame = +3
Query: 54 PFLLTCAIASAAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHA---NIR 218
P LL ++ SA + + ++ L Y P D + VV +T+ L+ N+
Sbjct: 5 PLLLLFSLCSAGLVLGSEHETRLVAKLFKDYSSVVRPVEDHRQVVEVTVGLQLIQLINVD 64
Query: 219 ESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYA 395
E V L+ W+D L WN ++G + + SE++WRPD+VL N A GD+A
Sbjct: 65 EVNQIVTTNVRLKQQWVDYNLKWNPDDYGGVKKIHIPSEKIWRPDLVLYNNA---DGDFA 121
Query: 396 L 398
+
Sbjct: 122 I 122
>BC006314-1|AAH06314.1| 269|Homo sapiens CHRNA1 protein protein.
Length = 269
Score = 51.2 bits (117), Expect = 5e-06
Identities = 36/121 (29%), Positives = 58/121 (47%), Gaps = 6/121 (4%)
Frame = +3
Query: 54 PFLLTCAIASAAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHA---NIR 218
P LL ++ SA + + ++ L Y P D + VV +T+ L+ N+
Sbjct: 5 PLLLLFSLCSAGLVLGSEHETRLVAKLFKDYSSVVRPVEDHRQVVEVTVGLQLIQLINVD 64
Query: 219 ESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYA 395
E V L+ W+D L WN ++G + + SE++WRPD+VL N A GD+A
Sbjct: 65 EVNQIVTTNVRLKQQWVDYNLKWNPDDYGGVKKIHIPSEKIWRPDLVLYNNA---DGDFA 121
Query: 396 L 398
+
Sbjct: 122 I 122
>AC018890-1|AAY14687.1| 457|Homo sapiens unknown protein.
Length = 457
Score = 51.2 bits (117), Expect = 5e-06
Identities = 36/121 (29%), Positives = 58/121 (47%), Gaps = 6/121 (4%)
Frame = +3
Query: 54 PFLLTCAIASAAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHA---NIR 218
P LL ++ SA + + ++ L Y P D + VV +T+ L+ N+
Sbjct: 5 PLLLLFSLCSAGLVLGSEHETRLVAKLFKDYSSVVRPVEDHRQVVEVTVGLQLIQLINVD 64
Query: 219 ESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYA 395
E V L+ W+D L WN ++G + + SE++WRPD+VL N A GD+A
Sbjct: 65 EVNQIVTTNVRLKQQWVDYNLKWNPDDYGGVKKIHIPSEKIWRPDLVLYNNA---DGDFA 121
Query: 396 L 398
+
Sbjct: 122 I 122
>BC111802-1|AAI11803.1| 465|Homo sapiens CHRNG protein protein.
Length = 465
Score = 48.8 bits (111), Expect = 2e-05
Identities = 33/114 (28%), Positives = 51/114 (44%), Gaps = 6/114 (5%)
Frame = +3
Query: 54 PFLLTCAIASAAECENATSLSLMIDSLLATYDRESPPDSKI--VVNLTLHLRHANI---R 218
P LL +A + ++ L+ YD P + VVN++L L N+
Sbjct: 7 PLLLLLLLAVCLGAQGRNQEERLLADLMQNYDPNLRPAERDSDVVNVSLKLTLTNLISLN 66
Query: 219 ESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAAT 377
E E + ++M W D RL W+ ++ G V S +WRPD+VL N + T
Sbjct: 67 EREEALTTNVWIEMQWCDYRLRWDPRDYEGLWVLRVPSTMVWRPDIVLENKSQT 120
>X68275-1|CAA48336.1| 451|Homo sapiens nicotinic receptor beta 4
subunit protein.
Length = 451
Score = 47.2 bits (107), Expect = 7e-05
Identities = 31/119 (26%), Positives = 53/119 (44%), Gaps = 3/119 (2%)
Frame = +3
Query: 174 IVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 347
I + L L L ++ E + + L+ W D RL+WN+ + G + + ++R+W P
Sbjct: 7 ISIKLQLSLAQLISVNERDEIMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLP 66
Query: 348 DVVLL-NAAATTAGDYALRARVSNNXSVSXIKRLDISTPISMXLXNWPNDMXTCTFQVR 521
D+VL NA T V +N SV + + + + +P D CT + R
Sbjct: 67 DIVLYNNADGTYEVSVYTNLIVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFR 125
>BC096083-1|AAH96083.1| 198|Homo sapiens CHRNB4 protein protein.
Length = 198
Score = 46.8 bits (106), Expect = 1e-04
Identities = 33/123 (26%), Positives = 58/123 (47%), Gaps = 8/123 (6%)
Frame = +3
Query: 48 LLPFLLTCAIASAAECENATSLSLMIDSLL--ATYDRESPP--DSKIVVNLTLHLRHA-- 209
L+ F L A+ C A + ++D LL Y+ P S ++++ L L A
Sbjct: 7 LVLFFLV-ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQL 65
Query: 210 -NIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTA 383
++ E E + L+ W D RL+WN+ + G + + ++R+W PD+VL N + T
Sbjct: 66 ISVNEREQIMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNKSLRTG 125
Query: 384 GDY 392
+
Sbjct: 126 STW 128
>BC096081-1|AAH96081.1| 198|Homo sapiens CHRNB4 protein protein.
Length = 198
Score = 46.8 bits (106), Expect = 1e-04
Identities = 33/123 (26%), Positives = 58/123 (47%), Gaps = 8/123 (6%)
Frame = +3
Query: 48 LLPFLLTCAIASAAECENATSLSLMIDSLL--ATYDRESPP--DSKIVVNLTLHLRHA-- 209
L+ F L A+ C A + ++D LL Y+ P S ++++ L L A
Sbjct: 7 LVLFFLV-ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQL 65
Query: 210 -NIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTA 383
++ E E + L+ W D RL+WN+ + G + + ++R+W PD+VL N + T
Sbjct: 66 ISVNEREQIMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNKSLRTG 125
Query: 384 GDY 392
+
Sbjct: 126 STW 128
>Y08417-1|CAA69694.1| 458|Homo sapiens nicotinic acetylcholine
receptor beta3 subunit precursor protein.
Length = 458
Score = 45.6 bits (103), Expect = 2e-04
Identities = 26/90 (28%), Positives = 41/90 (45%), Gaps = 2/90 (2%)
Frame = +3
Query: 252 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLL-NAAATTAGDYALRARVSNNXS 425
L+ W D +L WN ++ G + V SE LW PD+VL NA G + V +N +
Sbjct: 81 LKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFEGSLMTKVIVKSNGT 140
Query: 426 VSXIKRLDISTPISMXLXNWPNDMXTCTFQ 515
V + +M + +P D C+ +
Sbjct: 141 VVWTPPASYKSSCTMDVTFFPFDRQNCSMK 170
>X67513-1|CAA47851.1| 423|Homo sapiens nicotinic acetylcholine
receptor beta-3 subunit protein.
Length = 423
Score = 45.6 bits (103), Expect = 2e-04
Identities = 26/90 (28%), Positives = 41/90 (45%), Gaps = 2/90 (2%)
Frame = +3
Query: 252 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLL-NAAATTAGDYALRARVSNNXS 425
L+ W D +L WN ++ G + V SE LW PD+VL NA G + V +N +
Sbjct: 46 LKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFEGSLMTKVIVKSNGT 105
Query: 426 VSXIKRLDISTPISMXLXNWPNDMXTCTFQ 515
V + +M + +P D C+ +
Sbjct: 106 VVWTPPASYKSSCTMDVTFFPFDRQNCSMK 135
>X14830-1|CAA32939.1| 501|Homo sapiens protein ( Human mRNA for
muscle acetylcholine receptor beta-subunit. ).
Length = 501
Score = 45.6 bits (103), Expect = 2e-04
Identities = 27/74 (36%), Positives = 41/74 (55%), Gaps = 2/74 (2%)
Frame = +3
Query: 150 RESPPDSKIVVNLTL-HLRHANIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLV 323
RE ++ V L L L N ++ E + ++ DL+ W D RLSW+ E G + +
Sbjct: 46 REVGDRVRVSVGLILAQLISLNEKDEEMSTKVYLDLE--WTDYRLSWDPAEHDGIDSLRI 103
Query: 324 SSERLWRPDVVLLN 365
++E +W PDVVLLN
Sbjct: 104 TAESVWLPDVVLLN 117
>U62438-1|AAB40116.1| 458|Homo sapiens nicotinic acetylcholine
receptor beta3 subunit precursor protein.
Length = 458
Score = 45.6 bits (103), Expect = 2e-04
Identities = 26/90 (28%), Positives = 41/90 (45%), Gaps = 2/90 (2%)
Frame = +3
Query: 252 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLL-NAAATTAGDYALRARVSNNXS 425
L+ W D +L WN ++ G + V SE LW PD+VL NA G + V +N +
Sbjct: 81 LKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFEGSLMTKVIVKSNGT 140
Query: 426 VSXIKRLDISTPISMXLXNWPNDMXTCTFQ 515
V + +M + +P D C+ +
Sbjct: 141 VVWTPPASYKSSCTMDVTFFPFDRQNCSMK 170
>BC110597-1|AAI10598.1| 411|Homo sapiens ligand-gated ion channel,
zinc activated 1 protein.
Length = 411
Score = 45.6 bits (103), Expect = 2e-04
Identities = 24/86 (27%), Positives = 39/86 (45%)
Frame = +3
Query: 252 LQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNXSVS 431
L+++W+D RL+WN + E LW P + +L A D + +ARV + V
Sbjct: 86 LRLSWLDTRLAWNTSAHPRHAITLPWESLWTPRLTILEALWVDWRDQSPQARVDQDGHVK 145
Query: 432 XIKRLDISTPISMXLXNWPNDMXTCT 509
L T + L ++P D C+
Sbjct: 146 LNLALTTETNCNFELLHFPRDHSNCS 171
>BC069788-1|AAH69788.1| 458|Homo sapiens cholinergic receptor,
nicotinic, beta 3 protein.
Length = 458
Score = 45.6 bits (103), Expect = 2e-04
Identities = 26/90 (28%), Positives = 41/90 (45%), Gaps = 2/90 (2%)
Frame = +3
Query: 252 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLL-NAAATTAGDYALRARVSNNXS 425
L+ W D +L WN ++ G + V SE LW PD+VL NA G + V +N +
Sbjct: 81 LKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFEGSLMTKVIVKSNGT 140
Query: 426 VSXIKRLDISTPISMXLXNWPNDMXTCTFQ 515
V + +M + +P D C+ +
Sbjct: 141 VVWTPPASYKSSCTMDVTFFPFDRQNCSMK 170
>BC069703-1|AAH69703.1| 458|Homo sapiens cholinergic receptor,
nicotinic, beta 3 protein.
Length = 458
Score = 45.6 bits (103), Expect = 2e-04
Identities = 26/90 (28%), Positives = 41/90 (45%), Gaps = 2/90 (2%)
Frame = +3
Query: 252 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLL-NAAATTAGDYALRARVSNNXS 425
L+ W D +L WN ++ G + V SE LW PD+VL NA G + V +N +
Sbjct: 81 LKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFEGSLMTKVIVKSNGT 140
Query: 426 VSXIKRLDISTPISMXLXNWPNDMXTCTFQ 515
V + +M + +P D C+ +
Sbjct: 141 VVWTPPASYKSSCTMDVTFFPFDRQNCSMK 170
>BC069681-1|AAH69681.1| 458|Homo sapiens cholinergic receptor,
nicotinic, beta 3 protein.
Length = 458
Score = 45.6 bits (103), Expect = 2e-04
Identities = 26/90 (28%), Positives = 41/90 (45%), Gaps = 2/90 (2%)
Frame = +3
Query: 252 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLL-NAAATTAGDYALRARVSNNXS 425
L+ W D +L WN ++ G + V SE LW PD+VL NA G + V +N +
Sbjct: 81 LKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFEGSLMTKVIVKSNGT 140
Query: 426 VSXIKRLDISTPISMXLXNWPNDMXTCTFQ 515
V + +M + +P D C+ +
Sbjct: 141 VVWTPPASYKSSCTMDVTFFPFDRQNCSMK 170
>BC023553-1|AAH23553.1| 501|Homo sapiens cholinergic receptor,
nicotinic, beta 1 (muscle) protein.
Length = 501
Score = 45.6 bits (103), Expect = 2e-04
Identities = 27/74 (36%), Positives = 41/74 (55%), Gaps = 2/74 (2%)
Frame = +3
Query: 150 RESPPDSKIVVNLTL-HLRHANIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLV 323
RE ++ V L L L N ++ E + ++ DL+ W D RLSW+ E G + +
Sbjct: 46 REVGDRVRVSVGLILAQLISLNEKDEEMSTKVYLDLE--WTDYRLSWDPAEHDGIDSLRI 103
Query: 324 SSERLWRPDVVLLN 365
++E +W PDVVLLN
Sbjct: 104 TAESVWLPDVVLLN 117
>BC011371-1|AAH11371.1| 501|Homo sapiens cholinergic receptor,
nicotinic, beta 1 (muscle) protein.
Length = 501
Score = 45.6 bits (103), Expect = 2e-04
Identities = 27/74 (36%), Positives = 41/74 (55%), Gaps = 2/74 (2%)
Frame = +3
Query: 150 RESPPDSKIVVNLTL-HLRHANIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLV 323
RE ++ V L L L N ++ E + ++ DL+ W D RLSW+ E G + +
Sbjct: 46 REVGDRVRVSVGLILAQLISLNEKDEEMSTKVYLDLE--WTDYRLSWDPAEHDGIDSLRI 103
Query: 324 SSERLWRPDVVLLN 365
++E +W PDVVLLN
Sbjct: 104 TAESVWLPDVVLLN 117
>AK122638-1|BAC85499.1| 266|Homo sapiens yte protein of 76kDa)
(LCP2). protein.
Length = 266
Score = 45.6 bits (103), Expect = 2e-04
Identities = 24/86 (27%), Positives = 39/86 (45%)
Frame = +3
Query: 252 LQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNXSVS 431
L+++W+D RL+WN + E LW P + +L A D + +ARV + V
Sbjct: 87 LRLSWLDTRLAWNTSAHPRHAITLPWESLWTPRLTILEALWVDWRDQSPQARVDQDGHVK 146
Query: 432 XIKRLDISTPISMXLXNWPNDMXTCT 509
L T + L ++P D C+
Sbjct: 147 LNLALTTETNCNFELLHFPRDHSNCS 172
>AF512521-1|AAO20969.1| 411|Homo sapiens ligand-gated ion channel
subunit protein.
Length = 411
Score = 45.6 bits (103), Expect = 2e-04
Identities = 24/86 (27%), Positives = 39/86 (45%)
Frame = +3
Query: 252 LQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNXSVS 431
L+++W+D RL+WN + E LW P + +L A D + +ARV + V
Sbjct: 86 LRLSWLDTRLAWNTSAHPRHAITLPWESLWTPRLTILEALWVDWRDQSPQARVDQDGHVK 145
Query: 432 XIKRLDISTPISMXLXNWPNDMXTCT 509
L T + L ++P D C+
Sbjct: 146 LNLALTTETNCNFELLHFPRDHSNCS 171
>AF140765-1|AAD33063.1| 458|Homo sapiens neuronal acetylcholine
receptor beta-3 subunit precursor protein.
Length = 458
Score = 45.6 bits (103), Expect = 2e-04
Identities = 26/90 (28%), Positives = 41/90 (45%), Gaps = 2/90 (2%)
Frame = +3
Query: 252 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLL-NAAATTAGDYALRARVSNNXS 425
L+ W D +L WN ++ G + V SE LW PD+VL NA G + V +N +
Sbjct: 81 LKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFEGSLMTKVIVKSNGT 140
Query: 426 VSXIKRLDISTPISMXLXNWPNDMXTCTFQ 515
V + +M + +P D C+ +
Sbjct: 141 VVWTPPASYKSSCTMDVTFFPFDRQNCSMK 170
>X01715-1|CAA25861.1| 520|Homo sapiens acetylcholine receptor gamma
chain precursor protein.
Length = 520
Score = 45.2 bits (102), Expect = 3e-04
Identities = 35/114 (30%), Positives = 52/114 (45%), Gaps = 6/114 (5%)
Frame = +3
Query: 42 IILLPFLLTCAIASAAECENATSLSLMIDSLLATYDRESPPDSKI--VVNLTLHLRHANI 215
++LL L C + N L+ D L+ YD P + VVN++L L N+
Sbjct: 8 LLLLLLLAVCLGGTQRNLRNQEE-RLLAD-LMQNYDPNLRPAERDSDVVNVSLKLTLTNL 65
Query: 216 ---RESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLN 365
E E + ++M W D RL W+ ++ G V S +WRPD+VL N
Sbjct: 66 ISLNEREEALTTNVWIEMQWCDYRLRWDPRDYEGLWVLRVPSTMVWRPDIVLEN 119
>BT006897-1|AAP35543.1| 505|Homo sapiens cholinergic receptor,
nicotinic, alpha polypeptide 3 protein.
Length = 505
Score = 45.2 bits (102), Expect = 3e-04
Identities = 36/168 (21%), Positives = 73/168 (43%), Gaps = 5/168 (2%)
Frame = +3
Query: 27 MSTTYIILLPFLLTCAIASAAECENATSLSLMID--SLLATYDRESPPDSKIVVNLTLHL 200
+S ++LL L +A A+E E+ L D ++ S P ++++ + +
Sbjct: 12 LSPPRLLLLLLLSLLPVARASEAEHRLFERLFEDYNEIIRPVANVSDP---VIIHFEVSM 68
Query: 201 RH-ANIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLL-NAA 371
+ E + L+ W D +L WN ++G + ++ V ++++W+PD+VL NA
Sbjct: 69 SQLVKVDEVNQIMETNLWLKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAV 128
Query: 372 ATTAGDYALRARVSNNXSVSXIKRLDISTPISMXLXNWPNDMXTCTFQ 515
D +A + V+ I + + + +P D CT +
Sbjct: 129 GDFQVDDKTKALLKYTGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMK 176
>BT006646-1|AAP35292.1| 489|Homo sapiens cholinergic receptor,
nicotinic, alpha polypeptide 3 protein.
Length = 489
Score = 45.2 bits (102), Expect = 3e-04
Identities = 36/168 (21%), Positives = 73/168 (43%), Gaps = 5/168 (2%)
Frame = +3
Query: 27 MSTTYIILLPFLLTCAIASAAECENATSLSLMID--SLLATYDRESPPDSKIVVNLTLHL 200
+S ++LL L +A A+E E+ L D ++ S P ++++ + +
Sbjct: 12 LSPPRLLLLLLLSLLPVARASEAEHRLFERLFEDYNEIIRPVANVSDP---VIIHFEVSM 68
Query: 201 RH-ANIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLL-NAA 371
+ E + L+ W D +L WN ++G + ++ V ++++W+PD+VL NA
Sbjct: 69 SQLVKVDEVNQIMETNLWLKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAV 128
Query: 372 ATTAGDYALRARVSNNXSVSXIKRLDISTPISMXLXNWPNDMXTCTFQ 515
D +A + V+ I + + + +P D CT +
Sbjct: 129 GDFQVDDKTKALLKYTGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMK 176
>BC113575-1|AAI13576.1| 479|Homo sapiens cholinergic receptor,
nicotinic, alpha 9 protein.
Length = 479
Score = 45.2 bits (102), Expect = 3e-04
Identities = 28/102 (27%), Positives = 51/102 (50%), Gaps = 6/102 (5%)
Frame = +3
Query: 84 AAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHANIRESESTVRILAD-- 251
AAE + + + L Y P D+ V+N+TL + + I++ + +IL
Sbjct: 22 AAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQITLSQIKDMDERNQILTAYL 81
Query: 252 -LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA 371
++ W D L+W+ ++ G + + S+ +WRPD+VL N A
Sbjct: 82 WIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKA 123
>BC113549-1|AAI13550.1| 479|Homo sapiens cholinergic receptor,
nicotinic, alpha 9 protein.
Length = 479
Score = 45.2 bits (102), Expect = 3e-04
Identities = 28/102 (27%), Positives = 51/102 (50%), Gaps = 6/102 (5%)
Frame = +3
Query: 84 AAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHANIRESESTVRILAD-- 251
AAE + + + L Y P D+ V+N+TL + + I++ + +IL
Sbjct: 22 AAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQITLSQIKDMDERNQILTAYL 81
Query: 252 -LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA 371
++ W D L+W+ ++ G + + S+ +WRPD+VL N A
Sbjct: 82 WIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKA 123
>BC006114-1|AAH06114.1| 489|Homo sapiens CHRNA3 protein protein.
Length = 489
Score = 45.2 bits (102), Expect = 3e-04
Identities = 36/168 (21%), Positives = 73/168 (43%), Gaps = 5/168 (2%)
Frame = +3
Query: 27 MSTTYIILLPFLLTCAIASAAECENATSLSLMID--SLLATYDRESPPDSKIVVNLTLHL 200
+S ++LL L +A A+E E+ L D ++ S P ++++ + +
Sbjct: 12 LSPPRLLLLLLLSLLPVARASEAEHRLFERLFEDYNEIIRPVANVSDP---VIIHFEVSM 68
Query: 201 RH-ANIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLL-NAA 371
+ E + L+ W D +L WN ++G + ++ V ++++W+PD+VL NA
Sbjct: 69 SQLVKVDEVNQIMETNLWLKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAV 128
Query: 372 ATTAGDYALRARVSNNXSVSXIKRLDISTPISMXLXNWPNDMXTCTFQ 515
D +A + V+ I + + + +P D CT +
Sbjct: 129 GDFQVDDKTKALLKYTGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMK 176
>BC002996-1|AAH02996.1| 505|Homo sapiens cholinergic receptor,
nicotinic, alpha 3 protein.
Length = 505
Score = 45.2 bits (102), Expect = 3e-04
Identities = 36/168 (21%), Positives = 73/168 (43%), Gaps = 5/168 (2%)
Frame = +3
Query: 27 MSTTYIILLPFLLTCAIASAAECENATSLSLMID--SLLATYDRESPPDSKIVVNLTLHL 200
+S ++LL L +A A+E E+ L D ++ S P ++++ + +
Sbjct: 12 LSPPRLLLLLLLSLLPVARASEAEHRLFERLFEDYNEIIRPVANVSDP---VIIHFEVSM 68
Query: 201 RH-ANIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLL-NAA 371
+ E + L+ W D +L WN ++G + ++ V ++++W+PD+VL NA
Sbjct: 69 SQLVKVDEVNQIMETNLWLKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAV 128
Query: 372 ATTAGDYALRARVSNNXSVSXIKRLDISTPISMXLXNWPNDMXTCTFQ 515
D +A + V+ I + + + +P D CT +
Sbjct: 129 GDFQVDDKTKALLKYTGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMK 176
>BC001642-1|AAH01642.1| 505|Homo sapiens cholinergic receptor,
nicotinic, alpha 3 protein.
Length = 505
Score = 45.2 bits (102), Expect = 3e-04
Identities = 36/168 (21%), Positives = 73/168 (43%), Gaps = 5/168 (2%)
Frame = +3
Query: 27 MSTTYIILLPFLLTCAIASAAECENATSLSLMID--SLLATYDRESPPDSKIVVNLTLHL 200
+S ++LL L +A A+E E+ L D ++ S P ++++ + +
Sbjct: 12 LSPPRLLLLLLLSLLPVARASEAEHRLFERLFEDYNEIIRPVANVSDP---VIIHFEVSM 68
Query: 201 RH-ANIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLL-NAA 371
+ E + L+ W D +L WN ++G + ++ V ++++W+PD+VL NA
Sbjct: 69 SQLVKVDEVNQIMETNLWLKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAV 128
Query: 372 ATTAGDYALRARVSNNXSVSXIKRLDISTPISMXLXNWPNDMXTCTFQ 515
D +A + V+ I + + + +P D CT +
Sbjct: 129 GDFQVDDKTKALLKYTGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMK 176
>BC000513-1|AAH00513.1| 505|Homo sapiens cholinergic receptor,
nicotinic, alpha 3 protein.
Length = 505
Score = 45.2 bits (102), Expect = 3e-04
Identities = 36/168 (21%), Positives = 73/168 (43%), Gaps = 5/168 (2%)
Frame = +3
Query: 27 MSTTYIILLPFLLTCAIASAAECENATSLSLMID--SLLATYDRESPPDSKIVVNLTLHL 200
+S ++LL L +A A+E E+ L D ++ S P ++++ + +
Sbjct: 12 LSPPRLLLLLLLSLLPVARASEAEHRLFERLFEDYNEIIRPVANVSDP---VIIHFEVSM 68
Query: 201 RH-ANIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLL-NAA 371
+ E + L+ W D +L WN ++G + ++ V ++++W+PD+VL NA
Sbjct: 69 SQLVKVDEVNQIMETNLWLKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAV 128
Query: 372 ATTAGDYALRARVSNNXSVSXIKRLDISTPISMXLXNWPNDMXTCTFQ 515
D +A + V+ I + + + +P D CT +
Sbjct: 129 GDFQVDDKTKALLKYTGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMK 176
>AY123244-1|AAM74523.1| 479|Homo sapiens nicotinic acetylcholine
receptor subunit alpha 9 protein.
Length = 479
Score = 45.2 bits (102), Expect = 3e-04
Identities = 28/102 (27%), Positives = 51/102 (50%), Gaps = 6/102 (5%)
Frame = +3
Query: 84 AAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHANIRESESTVRILAD-- 251
AAE + + + L Y P D+ V+N+TL + + I++ + +IL
Sbjct: 22 AAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQITLSQIKDMDERNQILTAYL 81
Query: 252 -LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA 371
++ W D L+W+ ++ G + + S+ +WRPD+VL N A
Sbjct: 82 WIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKA 123
>AJ243342-1|CAB65091.1| 479|Homo sapiens nicotinic acetylcholine
receptor alpha 9 subunit protein.
Length = 479
Score = 45.2 bits (102), Expect = 3e-04
Identities = 28/102 (27%), Positives = 51/102 (50%), Gaps = 6/102 (5%)
Frame = +3
Query: 84 AAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHANIRESESTVRILAD-- 251
AAE + + + L Y P D+ V+N+TL + + I++ + +IL
Sbjct: 22 AAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQITLSQIKDMDERNQILTAYL 81
Query: 252 -LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA 371
++ W D L+W+ ++ G + + S+ +WRPD+VL N A
Sbjct: 82 WIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKA 123
>AF385584-1|AAK68110.1| 489|Homo sapiens nicotinic cholinergic
receptor alpha 3 protein.
Length = 489
Score = 45.2 bits (102), Expect = 3e-04
Identities = 36/168 (21%), Positives = 73/168 (43%), Gaps = 5/168 (2%)
Frame = +3
Query: 27 MSTTYIILLPFLLTCAIASAAECENATSLSLMID--SLLATYDRESPPDSKIVVNLTLHL 200
+S ++LL L +A A+E E+ L D ++ S P ++++ + +
Sbjct: 6 LSPPRLLLLLLLSLLPVARASEAEHRLFERLFEDYNEIIRPVANVSDP---VIIHFEVSM 62
Query: 201 RH-ANIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLL-NAA 371
+ E + L+ W D +L WN ++G + ++ V ++++W+PD+VL NA
Sbjct: 63 SQLVKVDEVNQIMETNLWLKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAV 122
Query: 372 ATTAGDYALRARVSNNXSVSXIKRLDISTPISMXLXNWPNDMXTCTFQ 515
D +A + V+ I + + + +P D CT +
Sbjct: 123 GDFQVDDKTKALLKYTGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMK 170
>AF227732-1|AAF61920.1| 470|Homo sapiens nicotinic acetylcholine
receptor alpha 9 subunit protein.
Length = 470
Score = 45.2 bits (102), Expect = 3e-04
Identities = 28/102 (27%), Positives = 51/102 (50%), Gaps = 6/102 (5%)
Frame = +3
Query: 84 AAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHANIRESESTVRILAD-- 251
AAE + + + L Y P D+ V+N+TL + + I++ + +IL
Sbjct: 16 AAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQITLSQIKDMDERNQILTAYL 75
Query: 252 -LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA 371
++ W D L+W+ ++ G + + S+ +WRPD+VL N A
Sbjct: 76 WIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKA 117
>AC118275-1|AAY40986.1| 479|Homo sapiens unknown protein.
Length = 479
Score = 45.2 bits (102), Expect = 3e-04
Identities = 28/102 (27%), Positives = 51/102 (50%), Gaps = 6/102 (5%)
Frame = +3
Query: 84 AAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHANIRESESTVRILAD-- 251
AAE + + + L Y P D+ V+N+TL + + I++ + +IL
Sbjct: 22 AAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQITLSQIKDMDERNQILTAYL 81
Query: 252 -LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA 371
++ W D L+W+ ++ G + + S+ +WRPD+VL N A
Sbjct: 82 WIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKA 123
>AC092165-3|AAY24103.1| 520|Homo sapiens unknown protein.
Length = 520
Score = 45.2 bits (102), Expect = 3e-04
Identities = 35/114 (30%), Positives = 52/114 (45%), Gaps = 6/114 (5%)
Frame = +3
Query: 42 IILLPFLLTCAIASAAECENATSLSLMIDSLLATYDRESPPDSKI--VVNLTLHLRHANI 215
++LL L C + N L+ D L+ YD P + VVN++L L N+
Sbjct: 8 LLLLLLLAVCLGGTQRNLRNQEE-RLLAD-LMQNYDPNLRPAERDSDVVNVSLKLTLTNL 65
Query: 216 ---RESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLN 365
E E + ++M W D RL W+ ++ G V S +WRPD+VL N
Sbjct: 66 ISLNEREEALTTNVWIEMQWCDYRLRWDPRDYEGLWVLRVPSTMVWRPDIVLEN 119
>AB223030-1|BAE19924.1| 411|Homo sapiens ligand-gated ion-channel
receptor L2 protein.
Length = 411
Score = 45.2 bits (102), Expect = 3e-04
Identities = 24/86 (27%), Positives = 39/86 (45%)
Frame = +3
Query: 252 LQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNXSVS 431
L+++W+D RL+WN + E LW P + +L A D + +ARV + V
Sbjct: 86 LRLSWLDTRLAWNTSAHPRHAITLPWESLWTPRLTILEALWVDWRDQSPQARVDQDGHVK 145
Query: 432 XIKRLDISTPISMXLXNWPNDMXTCT 509
L T + L ++P D C+
Sbjct: 146 LNLALATETNCNFELLHFPRDHSNCS 171
>Y08418-1|CAA69695.1| 503|Homo sapiens nicotinic acetylcholine
receptor alpha3 subunit precursor protein.
Length = 503
Score = 44.4 bits (100), Expect = 5e-04
Identities = 36/161 (22%), Positives = 70/161 (43%), Gaps = 3/161 (1%)
Frame = +3
Query: 42 IILLPFLLTCAIASAAECENATSLSLMIDSLLATYDRESPPDSKIVVNLTLHLRH-ANIR 218
++LL LL A AS AE L + ++ S P ++++ + + +
Sbjct: 17 LLLLLSLLPVARASEAEHRLFERLFEDYNEIIRPVANVSDP---VIIHFEVSMSQLVKVD 73
Query: 219 ESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLL-NAAATTAGDY 392
E + L+ W D +L WN ++G + ++ V ++++W+PD+VL NA D
Sbjct: 74 EVNQIMETNLWLKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDD 133
Query: 393 ALRARVSNNXSVSXIKRLDISTPISMXLXNWPNDMXTCTFQ 515
+A + V+ I + + + +P D CT +
Sbjct: 134 KTKALLKYTGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMK 174
>U62432-1|AAB40110.1| 504|Homo sapiens nicotinic acetylcholine
receptor alpha3 subunit precursor protein.
Length = 504
Score = 44.4 bits (100), Expect = 5e-04
Identities = 36/161 (22%), Positives = 70/161 (43%), Gaps = 3/161 (1%)
Frame = +3
Query: 42 IILLPFLLTCAIASAAECENATSLSLMIDSLLATYDRESPPDSKIVVNLTLHLRH-ANIR 218
++LL LL A AS AE L + ++ S P ++++ + + +
Sbjct: 18 LLLLLSLLPVARASEAEHRLFERLFEDYNEIIRPVANVSDP---VIIHFEVSMSQLVKVD 74
Query: 219 ESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLL-NAAATTAGDY 392
E + L+ W D +L WN ++G + ++ V ++++W+PD+VL NA D
Sbjct: 75 EVNQIMETNLWLKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDD 134
Query: 393 ALRARVSNNXSVSXIKRLDISTPISMXLXNWPNDMXTCTFQ 515
+A + V+ I + + + +P D CT +
Sbjct: 135 KTKALLKYTGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMK 175
>M37981-1|AAA59942.1| 503|Homo sapiens neuronal nicotinic
acetylcholine receptor protein.
Length = 503
Score = 44.4 bits (100), Expect = 5e-04
Identities = 36/161 (22%), Positives = 70/161 (43%), Gaps = 3/161 (1%)
Frame = +3
Query: 42 IILLPFLLTCAIASAAECENATSLSLMIDSLLATYDRESPPDSKIVVNLTLHLRH-ANIR 218
++LL LL A AS AE L + ++ S P ++++ + + +
Sbjct: 17 LLLLLSLLPVARASEAEHRLFERLFEDYNEIIRPVANVSDP---VIIHFEVSMSQLVKVD 73
Query: 219 ESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLL-NAAATTAGDY 392
E + L+ W D +L WN ++G + ++ V ++++W+PD+VL NA D
Sbjct: 74 EVNQIMETNLWLKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDD 133
Query: 393 ALRARVSNNXSVSXIKRLDISTPISMXLXNWPNDMXTCTFQ 515
+A + V+ I + + + +P D CT +
Sbjct: 134 KTKALLKYTGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMK 174
>BC098443-1|AAH98443.1| 504|Homo sapiens cholinergic receptor,
nicotinic, alpha 3 protein.
Length = 504
Score = 44.4 bits (100), Expect = 5e-04
Identities = 36/161 (22%), Positives = 70/161 (43%), Gaps = 3/161 (1%)
Frame = +3
Query: 42 IILLPFLLTCAIASAAECENATSLSLMIDSLLATYDRESPPDSKIVVNLTLHLRH-ANIR 218
++LL LL A AS AE L + ++ S P ++++ + + +
Sbjct: 18 LLLLLSLLPVARASEAEHRLFERLFEDYNEIIRPVANVSDP---VIIHFEVSMSQLVKVD 74
Query: 219 ESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLL-NAAATTAGDY 392
E + L+ W D +L WN ++G + ++ V ++++W+PD+VL NA D
Sbjct: 75 EVNQIMETNLWLKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDD 134
Query: 393 ALRARVSNNXSVSXIKRLDISTPISMXLXNWPNDMXTCTFQ 515
+A + V+ I + + + +P D CT +
Sbjct: 135 KTKALLKYTGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMK 175
>AJ007783-1|CAA07682.1| 504|Homo sapiens nicotinic acetylcholine
receptor alpha-3 subunit protein.
Length = 504
Score = 44.4 bits (100), Expect = 5e-04
Identities = 36/161 (22%), Positives = 70/161 (43%), Gaps = 3/161 (1%)
Frame = +3
Query: 42 IILLPFLLTCAIASAAECENATSLSLMIDSLLATYDRESPPDSKIVVNLTLHLRH-ANIR 218
++LL LL A AS AE L + ++ S P ++++ + + +
Sbjct: 18 LLLLLSLLPVARASEAEHRLFERLFEDYNEIIRPVANVSDP---VIIHFEVSMSQLVKVD 74
Query: 219 ESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLL-NAAATTAGDY 392
E + L+ W D +L WN ++G + ++ V ++++W+PD+VL NA D
Sbjct: 75 EVNQIMETNLWLKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDD 134
Query: 393 ALRARVSNNXSVSXIKRLDISTPISMXLXNWPNDMXTCTFQ 515
+A + V+ I + + + +P D CT +
Sbjct: 135 KTKALLKYTGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMK 175
>Y16281-1|CAA76154.1| 529|Homo sapiens nicotinic acetylcholine
receptor alpha2 subunit precursor protein.
Length = 529
Score = 43.6 bits (98), Expect = 0.001
Identities = 26/87 (29%), Positives = 42/87 (48%), Gaps = 2/87 (2%)
Frame = +3
Query: 252 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLL-NAAATTAGDYALRARVSNNXS 425
L+ W D +L WN ++G T L V SE +W PD+VL NA A + +A + + +
Sbjct: 111 LKQEWSDYKLRWNPADFGNITSLRVPSEMIWIPDIVLYNNADGEFAVTHMTKAHLFSTGT 170
Query: 426 VSXIKRLDISTPISMXLXNWPNDMXTC 506
V + + S+ + +P D C
Sbjct: 171 VHWVPPAIYKSSCSIDVTFFPFDQQNC 197
>X53559-1|CAA37625.1| 474|Homo sapiens neuronal nicotinic
acetylcholine receptor alpha-3merase protein.
Length = 474
Score = 43.6 bits (98), Expect = 0.001
Identities = 23/90 (25%), Positives = 44/90 (48%), Gaps = 2/90 (2%)
Frame = +3
Query: 252 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLL-NAAATTAGDYALRARVSNNXS 425
L+ W D +L WN ++G + ++ V ++++W+PD+VL NA D +A +
Sbjct: 56 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 115
Query: 426 VSXIKRLDISTPISMXLXNWPNDMXTCTFQ 515
V+ I + + + +P D CT +
Sbjct: 116 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMK 145
>U62431-1|AAB40109.1| 529|Homo sapiens nicotinic acetylcholine
receptor alpha2 subunit precursor protein.
Length = 529
Score = 43.6 bits (98), Expect = 0.001
Identities = 26/87 (29%), Positives = 42/87 (48%), Gaps = 2/87 (2%)
Frame = +3
Query: 252 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLL-NAAATTAGDYALRARVSNNXS 425
L+ W D +L WN ++G T L V SE +W PD+VL NA A + +A + + +
Sbjct: 111 LKQEWSDYKLRWNPADFGNITSLRVPSEMIWIPDIVLYNNADGEFAVTHMTKAHLFSTGT 170
Query: 426 VSXIKRLDISTPISMXLXNWPNDMXTC 506
V + + S+ + +P D C
Sbjct: 171 VHWVPPAIYKSSCSIDVTFFPFDQQNC 197
>U77731-2|AAB38273.1| 360|Homo sapiens glycine receptor alpha 2B
subunit protein.
Length = 360
Score = 43.2 bits (97), Expect = 0.001
Identities = 36/133 (27%), Positives = 57/133 (42%), Gaps = 8/133 (6%)
Frame = +3
Query: 144 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 311
YD P+ K VN+T ++ +I E+ R+ L+ W D RL+++
Sbjct: 58 YDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDSRLAYSEYPDDSL 117
Query: 312 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNXSVSXIKRLDISTPISMXLX 479
S + +W+PD+ N D R+S N V RL ++ M L
Sbjct: 118 DLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLK 177
Query: 480 NWPNDMXTCTFQV 518
N+P D+ TCT Q+
Sbjct: 178 NFPMDVQTCTMQL 190
>S77554-1|AAB33983.1| 474|Homo sapiens GABAA receptor beta 2
subunit protein.
Length = 474
Score = 43.2 bits (97), Expect = 0.001
Identities = 39/170 (22%), Positives = 69/170 (40%), Gaps = 10/170 (5%)
Frame = +3
Query: 39 YIILLPFLLTCAIASAAECENATSLSLM---IDSLLATYDRESPPD---SKIVVNLTLHL 200
Y + F L A A + +++SL+ +D LL YD PD + V + + +
Sbjct: 9 YFGIWSFPLIIAAVCAQSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDI 68
Query: 201 RHAN-IRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAAT 377
+ + E + Q W DKRLS+N + +++LW PD LN +
Sbjct: 69 ASIDMVSEVNMDYTLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLNDKKS 128
Query: 378 TAGDYALR---ARVSNNXSVSXIKRLDISTPISMXLXNWPNDMXTCTFQV 518
++ R+ + +V R+ + M L +P D CT ++
Sbjct: 129 FVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEI 178
>S77553-1|AAB33982.1| 512|Homo sapiens GABAA receptor beta 2
subunit protein.
Length = 512
Score = 43.2 bits (97), Expect = 0.001
Identities = 39/170 (22%), Positives = 69/170 (40%), Gaps = 10/170 (5%)
Frame = +3
Query: 39 YIILLPFLLTCAIASAAECENATSLSLM---IDSLLATYDRESPPD---SKIVVNLTLHL 200
Y + F L A A + +++SL+ +D LL YD PD + V + + +
Sbjct: 9 YFGIWSFPLIIAAVCAQSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDI 68
Query: 201 RHAN-IRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAAT 377
+ + E + Q W DKRLS+N + +++LW PD LN +
Sbjct: 69 ASIDMVSEVNMDYTLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLNDKKS 128
Query: 378 TAGDYALR---ARVSNNXSVSXIKRLDISTPISMXLXNWPNDMXTCTFQV 518
++ R+ + +V R+ + M L +P D CT ++
Sbjct: 129 FVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEI 178
>S67368-1|AAB29370.1| 474|Homo sapiens gamma-aminobutyric acid A
receptor beta 2 subunit protein.
Length = 474
Score = 43.2 bits (97), Expect = 0.001
Identities = 39/170 (22%), Positives = 69/170 (40%), Gaps = 10/170 (5%)
Frame = +3
Query: 39 YIILLPFLLTCAIASAAECENATSLSLM---IDSLLATYDRESPPD---SKIVVNLTLHL 200
Y + F L A A + +++SL+ +D LL YD PD + V + + +
Sbjct: 9 YFGIWSFPLIIAAVCAQSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDI 68
Query: 201 RHAN-IRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAAT 377
+ + E + Q W DKRLS+N + +++LW PD LN +
Sbjct: 69 ASIDMVSEVNMDYTLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLNDKKS 128
Query: 378 TAGDYALR---ARVSNNXSVSXIKRLDISTPISMXLXNWPNDMXTCTFQV 518
++ R+ + +V R+ + M L +P D CT ++
Sbjct: 129 FVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEI 178
>DQ644022-1|ABG35128.1| 456|Homo sapiens 5-HT3 receptor subunit E
splice variant HTR3Ea protein.
Length = 456
Score = 43.2 bits (97), Expect = 0.001
Identities = 37/171 (21%), Positives = 74/171 (43%), Gaps = 8/171 (4%)
Frame = +3
Query: 21 HKMSTTYIILLPFLLTC-AIASAAECENATSLSLMIDSLLATYDRES-PPDSKIVVNLTL 194
H+ ++ +LL FLL + C +L + ++R+ P + I V +
Sbjct: 7 HRKRFSFYLLLGFLLQGRGVTFTINCSGFGQHGADPTALNSVFNRKPFRPVTNISVPTQV 66
Query: 195 HLRHAN--IRESESTVRILAD---LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVV 356
++ A I + + +L+ L+M W + +SWN E G + ++++ LW PD+
Sbjct: 67 NISFAMSAILDVNEQLHLLSSFLWLEMVWDNPFISWNPEECEGITKMSMAAKNLWLPDIF 126
Query: 357 LLNAAATTAGDYALRARVSNNXSVSXIKRLDISTPISMXLXNWPNDMXTCT 509
++ L A VSN + K + + + ++ + +P D CT
Sbjct: 127 IIELMDVDKTPKGLTAYVSNEGRIRYKKPMKVDSICNLDIFYFPFDQQNCT 177
>CR450343-1|CAG29339.1| 452|Homo sapiens GLRA2 protein.
Length = 452
Score = 43.2 bits (97), Expect = 0.001
Identities = 36/133 (27%), Positives = 57/133 (42%), Gaps = 8/133 (6%)
Frame = +3
Query: 144 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 311
YD P+ K VN+T ++ +I E+ R+ L+ W D RL+++
Sbjct: 58 YDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDSRLAYSEYPDDSL 117
Query: 312 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNXSVSXIKRLDISTPISMXLX 479
S + +W+PD+ N D R+S N V RL ++ M L
Sbjct: 118 DLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLK 177
Query: 480 NWPNDMXTCTFQV 518
N+P D+ TCT Q+
Sbjct: 178 NFPMDVQTCTMQL 190
>BC105639-1|AAI05640.1| 474|Homo sapiens GABRB2 protein protein.
Length = 474
Score = 43.2 bits (97), Expect = 0.001
Identities = 39/170 (22%), Positives = 69/170 (40%), Gaps = 10/170 (5%)
Frame = +3
Query: 39 YIILLPFLLTCAIASAAECENATSLSLM---IDSLLATYDRESPPD---SKIVVNLTLHL 200
Y + F L A A + +++SL+ +D LL YD PD + V + + +
Sbjct: 9 YFGIWSFPLIIAAVCAQSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDI 68
Query: 201 RHAN-IRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAAT 377
+ + E + Q W DKRLS+N + +++LW PD LN +
Sbjct: 69 ASIDMVSEVNMDYTLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLNDKKS 128
Query: 378 TAGDYALR---ARVSNNXSVSXIKRLDISTPISMXLXNWPNDMXTCTFQV 518
++ R+ + +V R+ + M L +P D CT ++
Sbjct: 129 FVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEI 178
>BC099719-1|AAH99719.1| 474|Homo sapiens GABRB2 protein protein.
Length = 474
Score = 43.2 bits (97), Expect = 0.001
Identities = 39/170 (22%), Positives = 69/170 (40%), Gaps = 10/170 (5%)
Frame = +3
Query: 39 YIILLPFLLTCAIASAAECENATSLSLM---IDSLLATYDRESPPD---SKIVVNLTLHL 200
Y + F L A A + +++SL+ +D LL YD PD + V + + +
Sbjct: 9 YFGIWSFPLIIAAVCAQSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDI 68
Query: 201 RHAN-IRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAAT 377
+ + E + Q W DKRLS+N + +++LW PD LN +
Sbjct: 69 ASIDMVSEVNMDYTLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLNDKKS 128
Query: 378 TAGDYALR---ARVSNNXSVSXIKRLDISTPISMXLXNWPNDMXTCTFQV 518
++ R+ + +V R+ + M L +P D CT ++
Sbjct: 129 FVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEI 178
>BC099705-1|AAH99705.1| 474|Homo sapiens GABRB2 protein protein.
Length = 474
Score = 43.2 bits (97), Expect = 0.001
Identities = 39/170 (22%), Positives = 69/170 (40%), Gaps = 10/170 (5%)
Frame = +3
Query: 39 YIILLPFLLTCAIASAAECENATSLSLM---IDSLLATYDRESPPD---SKIVVNLTLHL 200
Y + F L A A + +++SL+ +D LL YD PD + V + + +
Sbjct: 9 YFGIWSFPLIIAAVCAQSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDI 68
Query: 201 RHAN-IRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAAT 377
+ + E + Q W DKRLS+N + +++LW PD LN +
Sbjct: 69 ASIDMVSEVNMDYTLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLNDKKS 128
Query: 378 TAGDYALR---ARVSNNXSVSXIKRLDISTPISMXLXNWPNDMXTCTFQV 518
++ R+ + +V R+ + M L +P D CT ++
Sbjct: 129 FVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEI 178
>AY437084-1|AAR87843.1| 452|Homo sapiens glycine receptor alpha2
subunit B protein.
Length = 452
Score = 43.2 bits (97), Expect = 0.001
Identities = 36/133 (27%), Positives = 57/133 (42%), Gaps = 8/133 (6%)
Frame = +3
Query: 144 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 311
YD P+ K VN+T ++ +I E+ R+ L+ W D RL+++
Sbjct: 58 YDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDSRLAYSEYPDDSL 117
Query: 312 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNXSVSXIKRLDISTPISMXLX 479
S + +W+PD+ N D R+S N V RL ++ M L
Sbjct: 118 DLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLK 177
Query: 480 NWPNDMXTCTFQV 518
N+P D+ TCT Q+
Sbjct: 178 NFPMDVQTCTMQL 190
>Y08419-1|CAA69696.1| 468|Homo sapiens nicotinic acetylcholine
receptor alpha5 subunit precursor protein.
Length = 468
Score = 42.7 bits (96), Expect = 0.002
Identities = 29/138 (21%), Positives = 60/138 (43%), Gaps = 6/138 (4%)
Frame = +3
Query: 120 MIDSLLATYDRESPP----DSKIVVNLTLHLRH-ANIRESESTVRILADLQMNWIDKRLS 284
++ L Y+R P + KI + L + ++ E + L+ WID +L
Sbjct: 50 LLKDLFQDYERWVRPVEHLNDKIKIKFGLAISQLVDVDEKNQLMTTNVWLKQEWIDVKLR 109
Query: 285 WNAGEWG-CSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNXSVSXIKRLDISTP 461
WN ++G V S+ +W PD+VL + A + + + N +V+ + +
Sbjct: 110 WNPDDYGGIKVIRVPSDSVWTPDIVLFDNADGRFEGTSTKTVIRYNGTVTWTPPANYKSS 169
Query: 462 ISMXLXNWPNDMXTCTFQ 515
++ + +P D+ C+ +
Sbjct: 170 CTIDVTFFPFDLQNCSMK 187
>X52008-1|CAA36257.1| 452|Homo sapiens inhibitory glycine receptor
protein.
Length = 452
Score = 42.7 bits (96), Expect = 0.002
Identities = 35/133 (26%), Positives = 57/133 (42%), Gaps = 8/133 (6%)
Frame = +3
Query: 144 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 311
YD P+ K VN+T ++ ++ E+ R+ L+ W D RL+++
Sbjct: 58 YDARIRPNFKGPPVNVTCNIFINSFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPDDSL 117
Query: 312 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNXSVSXIKRLDISTPISMXLX 479
S + +W+PD+ N D R+S N V RL ++ M L
Sbjct: 118 DLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLK 177
Query: 480 NWPNDMXTCTFQV 518
N+P D+ TCT Q+
Sbjct: 178 NFPMDVQTCTMQL 190
>U77731-1|AAB38272.1| 360|Homo sapiens glycine receptor alpha 2
subunit protein.
Length = 360
Score = 42.7 bits (96), Expect = 0.002
Identities = 35/133 (26%), Positives = 57/133 (42%), Gaps = 8/133 (6%)
Frame = +3
Query: 144 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 311
YD P+ K VN+T ++ ++ E+ R+ L+ W D RL+++
Sbjct: 58 YDARIRPNFKGPPVNVTCNIFINSFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPDDSL 117
Query: 312 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNXSVSXIKRLDISTPISMXLX 479
S + +W+PD+ N D R+S N V RL ++ M L
Sbjct: 118 DLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLK 177
Query: 480 NWPNDMXTCTFQV 518
N+P D+ TCT Q+
Sbjct: 178 NFPMDVQTCTMQL 190
>U62434-1|AAB40112.1| 468|Homo sapiens nicotinic acetylcholine
receptor alpha5 subunit precursor protein.
Length = 468
Score = 42.7 bits (96), Expect = 0.002
Identities = 29/138 (21%), Positives = 60/138 (43%), Gaps = 6/138 (4%)
Frame = +3
Query: 120 MIDSLLATYDRESPP----DSKIVVNLTLHLRH-ANIRESESTVRILADLQMNWIDKRLS 284
++ L Y+R P + KI + L + ++ E + L+ WID +L
Sbjct: 50 LLKDLFQDYERWVRPVEHLNDKIKIKFGLAISQLVDVDEKNQLMTTNVWLKQEWIDVKLR 109
Query: 285 WNAGEWG-CSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNXSVSXIKRLDISTP 461
WN ++G V S+ +W PD+VL + A + + + N +V+ + +
Sbjct: 110 WNPDDYGGIKVIRVPSDSVWTPDIVLFDNADGRFEGTSTKTVIRYNGTVTWTPPANYKSS 169
Query: 462 ISMXLXNWPNDMXTCTFQ 515
++ + +P D+ C+ +
Sbjct: 170 CTIDVTFFPFDLQNCSMK 187
>M59216-1|AAA35862.1| 474|Homo sapiens gamma-aminobutyric acid
receptor beta-1 subunit protein.
Length = 474
Score = 42.7 bits (96), Expect = 0.002
Identities = 37/168 (22%), Positives = 69/168 (41%), Gaps = 9/168 (5%)
Frame = +3
Query: 42 IILLPFLLT--CAIASAAECENATSLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRH 206
++ P ++T C S E N + + +D LL YD PD + V + + +
Sbjct: 12 LLSFPVMITMVCCAHSTNEPSNMSYVKETVDRLLKGYDIRLRPDFGGPPVDVGMRIDVAS 71
Query: 207 AN-IRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTA 383
+ + E + Q +W DKRLS++ + +++LW PD LN +
Sbjct: 72 IDMVSEVNMDYTLTMYFQQSWKDKRLSYSGIPLNLTLDNRVADQLWVPDTYFLNDKKSFV 131
Query: 384 GDYALR---ARVSNNXSVSXIKRLDISTPISMXLXNWPNDMXTCTFQV 518
++ R+ + +V R+ + M L +P D CT ++
Sbjct: 132 HGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEI 179
>BC101185-1|AAI01186.1| 374|Homo sapiens HTR3E protein protein.
Length = 374
Score = 42.7 bits (96), Expect = 0.002
Identities = 22/87 (25%), Positives = 41/87 (47%), Gaps = 1/87 (1%)
Frame = +3
Query: 252 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNXSV 428
L+M W + +SWN E G + ++++ LW PD+ ++ L A VSN +
Sbjct: 20 LEMVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEGRI 79
Query: 429 SXIKRLDISTPISMXLXNWPNDMXTCT 509
K + + + ++ + +P D CT
Sbjct: 80 RYKKPMKVDSICNLDIFYFPFDQQNCT 106
>BC101183-1|AAI01184.1| 471|Homo sapiens 5-hydroxytryptamine
(serotonin) receptor 3, family member E protein.
Length = 471
Score = 42.7 bits (96), Expect = 0.002
Identities = 22/87 (25%), Positives = 41/87 (47%), Gaps = 1/87 (1%)
Frame = +3
Query: 252 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNXSV 428
L+M W + +SWN E G + ++++ LW PD+ ++ L A VSN +
Sbjct: 106 LEMVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEGRI 165
Query: 429 SXIKRLDISTPISMXLXNWPNDMXTCT 509
K + + + ++ + +P D CT
Sbjct: 166 RYKKPMKVDSICNLDIFYFPFDQQNCT 192
>BC101182-1|AAI01183.1| 471|Homo sapiens 5-hydroxytryptamine
(serotonin) receptor 3, family member E protein.
Length = 471
Score = 42.7 bits (96), Expect = 0.002
Identities = 22/87 (25%), Positives = 41/87 (47%), Gaps = 1/87 (1%)
Frame = +3
Query: 252 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNXSV 428
L+M W + +SWN E G + ++++ LW PD+ ++ L A VSN +
Sbjct: 106 LEMVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEGRI 165
Query: 429 SXIKRLDISTPISMXLXNWPNDMXTCT 509
K + + + ++ + +P D CT
Sbjct: 166 RYKKPMKVDSICNLDIFYFPFDQQNCT 192
>BC033639-1|AAH33639.1| 468|Homo sapiens cholinergic receptor,
nicotinic, alpha 5 protein.
Length = 468
Score = 42.7 bits (96), Expect = 0.002
Identities = 29/138 (21%), Positives = 60/138 (43%), Gaps = 6/138 (4%)
Frame = +3
Query: 120 MIDSLLATYDRESPP----DSKIVVNLTLHLRH-ANIRESESTVRILADLQMNWIDKRLS 284
++ L Y+R P + KI + L + ++ E + L+ WID +L
Sbjct: 50 LLKDLFQDYERWVRPVEHLNDKIKIKFGLAISQLVDVDEKNQLMTTNVWLKQEWIDVKLR 109
Query: 285 WNAGEWG-CSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNXSVSXIKRLDISTP 461
WN ++G V S+ +W PD+VL + A + + + N +V+ + +
Sbjct: 110 WNPDDYGGIKVIRVPSDSVWTPDIVLFDNADGRFEGTSTKTVIRYNGTVTWTPPANYKSS 169
Query: 462 ISMXLXNWPNDMXTCTFQ 515
++ + +P D+ C+ +
Sbjct: 170 CTIDVTFFPFDLQNCSMK 187
>BC032864-1|AAH32864.1| 452|Homo sapiens glycine receptor, alpha 2
protein.
Length = 452
Score = 42.7 bits (96), Expect = 0.002
Identities = 35/133 (26%), Positives = 57/133 (42%), Gaps = 8/133 (6%)
Frame = +3
Query: 144 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 311
YD P+ K VN+T ++ ++ E+ R+ L+ W D RL+++
Sbjct: 58 YDARIRPNFKGPPVNVTCNIFINSFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPDDSL 117
Query: 312 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNXSVSXIKRLDISTPISMXLX 479
S + +W+PD+ N D R+S N V RL ++ M L
Sbjct: 118 DLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLK 177
Query: 480 NWPNDMXTCTFQV 518
N+P D+ TCT Q+
Sbjct: 178 NFPMDVQTCTMQL 190
>AY437083-1|AAR87842.1| 452|Homo sapiens glycine receptor alpha2
subunit A protein.
Length = 452
Score = 42.7 bits (96), Expect = 0.002
Identities = 35/133 (26%), Positives = 57/133 (42%), Gaps = 8/133 (6%)
Frame = +3
Query: 144 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 311
YD P+ K VN+T ++ ++ E+ R+ L+ W D RL+++
Sbjct: 58 YDARIRPNFKGPPVNVTCNIFINSFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPDDSL 117
Query: 312 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNXSVSXIKRLDISTPISMXLX 479
S + +W+PD+ N D R+S N V RL ++ M L
Sbjct: 118 DLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLK 177
Query: 480 NWPNDMXTCTFQV 518
N+P D+ TCT Q+
Sbjct: 178 NFPMDVQTCTMQL 190
>AY159813-1|AAO38167.2| 471|Homo sapiens 5-hydroxytryptamine
serotonin receptor 3E protein.
Length = 471
Score = 42.7 bits (96), Expect = 0.002
Identities = 22/87 (25%), Positives = 41/87 (47%), Gaps = 1/87 (1%)
Frame = +3
Query: 252 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNXSV 428
L+M W + +SWN E G + ++++ LW PD+ ++ L A VSN +
Sbjct: 106 LEMVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEGRI 165
Query: 429 SXIKRLDISTPISMXLXNWPNDMXTCT 509
K + + + ++ + +P D CT
Sbjct: 166 RYKKPMKVDSICNLDIFYFPFDQQNCT 192
>AJ306481-1|CAC34820.1| 468|Homo sapiens neuronal nicotinic
acetylcholine receptor alpha-5subunit protein.
Length = 468
Score = 42.7 bits (96), Expect = 0.002
Identities = 29/138 (21%), Positives = 60/138 (43%), Gaps = 6/138 (4%)
Frame = +3
Query: 120 MIDSLLATYDRESPP----DSKIVVNLTLHLRH-ANIRESESTVRILADLQMNWIDKRLS 284
++ L Y+R P + KI + L + ++ E + L+ WID +L
Sbjct: 50 LLKDLFQDYERWVRPVEHLNDKIKIKFGLAISQLVDVDEKNQLMTTNVWLKQEWIDVKLR 109
Query: 285 WNAGEWG-CSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNXSVSXIKRLDISTP 461
WN ++G V S+ +W PD+VL + A + + + N +V+ + +
Sbjct: 110 WNPDDYGGIKVIRVPSDSVWTPDIVLFDNADGRFEGTSTKTVIRYNGTVTWTPPANYKSS 169
Query: 462 ISMXLXNWPNDMXTCTFQ 515
++ + +P D+ C+ +
Sbjct: 170 CTIDVTFFPFDLQNCSMK 187
>AF053495-1|AAC35290.1| 452|Homo sapiens glycine receptor alpha 2
subunit protein.
Length = 452
Score = 42.7 bits (96), Expect = 0.002
Identities = 35/133 (26%), Positives = 57/133 (42%), Gaps = 8/133 (6%)
Frame = +3
Query: 144 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 311
YD P+ K VN+T ++ ++ E+ R+ L+ W D RL+++
Sbjct: 58 YDARIRPNFKGPPVNVTCNIFINSFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPDDSL 117
Query: 312 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNXSVSXIKRLDISTPISMXLX 479
S + +W+PD+ N D R+S N V RL ++ M L
Sbjct: 118 DLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLK 177
Query: 480 NWPNDMXTCTFQV 518
N+P D+ TCT Q+
Sbjct: 178 NFPMDVQTCTMQL 190
>X14767-1|CAA32875.1| 474|Homo sapiens GABA-A receptor beta 1
subunit protein.
Length = 474
Score = 41.9 bits (94), Expect = 0.003
Identities = 37/168 (22%), Positives = 68/168 (40%), Gaps = 9/168 (5%)
Frame = +3
Query: 42 IILLPFLLT--CAIASAAECENATSLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRH 206
++ P ++T C S E N + +D LL YD PD + V + + +
Sbjct: 12 LLSFPVMITMVCCAHSTNEPSNMPYVKETVDRLLKGYDIRLRPDFGGPPVDVGMRIDVAS 71
Query: 207 AN-IRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTA 383
+ + E + Q +W DKRLS++ + +++LW PD LN +
Sbjct: 72 IDMVSEVNMDYTLTMYFQQSWKDKRLSYSGIPLNLTLDNRVADQLWVPDTYFLNDKKSFV 131
Query: 384 GDYALR---ARVSNNXSVSXIKRLDISTPISMXLXNWPNDMXTCTFQV 518
++ R+ + +V R+ + M L +P D CT ++
Sbjct: 132 HGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEI 179
>M86383-1|AAC84176.1| 502|Homo sapiens nicotinic acetylcholine
receptor alpha 3 subunit precursor protein.
Length = 502
Score = 41.9 bits (94), Expect = 0.003
Identities = 37/164 (22%), Positives = 72/164 (43%), Gaps = 6/164 (3%)
Frame = +3
Query: 42 IILLPFLLTCAIASAAECENATSLSLMIDSLLATYDRESPPDSKIVVNLTLHLRH-ANIR 218
++LL LL A AS AE L + ++ S P ++++ + + +
Sbjct: 16 LLLLLSLLPVARASEAEHRLFERLFEDYNEIIRPVANVSDP---VIIHFEVSMSQLVKVD 72
Query: 219 ESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYA 395
E + L+ W D +L WN +G + ++ V ++++W+PD+VL N A GD+
Sbjct: 73 EVNQIMETNLWLKQIWNDYKLKWNPSGYGGAEFMRVPAQKIWKPDIVLYNNA---VGDFQ 129
Query: 396 L----RARVSNNXSVSXIKRLDISTPISMXLXNWPNDMXTCTFQ 515
+ +A + V+ I + + + +P D CT +
Sbjct: 130 VTTKTKALLKYTGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMK 173
>Z23141-1|CAA80672.1| 479|Homo sapiens cholinergic receptor,
nicotinic, alpha polypeptide 7 protein.
Length = 479
Score = 41.5 bits (93), Expect = 0.004
Identities = 17/41 (41%), Positives = 25/41 (60%), Gaps = 1/41 (2%)
Frame = +3
Query: 252 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA 371
LQM+W D L WN E+ G T ++W+PD++L N+A
Sbjct: 55 LQMSWTDHYLQWNVSEYPGVKTVRFPDGQIWKPDILLYNSA 95
>Y16282-1|CAA76155.1| 494|Homo sapiens nicotinic acetylcholine
receptor alpha6 subunit precursor protein.
Length = 494
Score = 41.5 bits (93), Expect = 0.004
Identities = 33/151 (21%), Positives = 65/151 (43%), Gaps = 10/151 (6%)
Frame = +3
Query: 93 CENATSLSLMIDSLLATYDRESPPDSKIVVNLTLHL-----RHANIRESESTVRILADLQ 257
C + + L + Y++ P + +T+H + AN+ E + L+
Sbjct: 28 CVGCATEERLFHKLFSHYNQFIRPVENVSDPVTVHFEVAITQLANVDEVNQIMETNLWLR 87
Query: 258 MNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNX 422
W D +L W+ E+ G T V ++++W+PD+VL N A GD+ + +A + N
Sbjct: 88 HIWNDYKLRWDPMEYDGIETLRVPADKIWKPDIVLYNNA---VGDFQVEGKTKALLKYNG 144
Query: 423 SVSXIKRLDISTPISMXLXNWPNDMXTCTFQ 515
++ + M + +P D C+ +
Sbjct: 145 MITWTPPAIFKSSCPMDITFFPFDHQNCSLK 175
>Y08420-1|CAA69697.1| 502|Homo sapiens nicotinic acetylcholine
receptor alpha7 subunit precursor protein.
Length = 502
Score = 41.5 bits (93), Expect = 0.004
Identities = 17/41 (41%), Positives = 25/41 (60%), Gaps = 1/41 (2%)
Frame = +3
Query: 252 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA 371
LQM+W D L WN E+ G T ++W+PD++L N+A
Sbjct: 78 LQMSWTDHYLQWNVSEYPGVKTVRFPDGQIWKPDILLYNSA 118
>X70297-1|CAA49778.1| 502|Homo sapiens neuronal nicotinic
acetylocholine receptor alpha-7 subunit protein.
Length = 502
Score = 41.5 bits (93), Expect = 0.004
Identities = 17/41 (41%), Positives = 25/41 (60%), Gaps = 1/41 (2%)
Frame = +3
Query: 252 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA 371
LQM+W D L WN E+ G T ++W+PD++L N+A
Sbjct: 78 LQMSWTDHYLQWNVSEYPGVKTVRFPDGQIWKPDILLYNSA 118
>U62436-1|AAB40114.1| 502|Homo sapiens nicotinic acetylcholine
receptor alpha7 subunit precursor protein.
Length = 502
Score = 41.5 bits (93), Expect = 0.004
Identities = 17/41 (41%), Positives = 25/41 (60%), Gaps = 1/41 (2%)
Frame = +3
Query: 252 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA 371
LQM+W D L WN E+ G T ++W+PD++L N+A
Sbjct: 78 LQMSWTDHYLQWNVSEYPGVKTVRFPDGQIWKPDILLYNSA 118
>U62435-1|AAB40113.1| 494|Homo sapiens nicotinic acetylcholine
receptor alpha6 subunit precursor protein.
Length = 494
Score = 41.5 bits (93), Expect = 0.004
Identities = 33/151 (21%), Positives = 65/151 (43%), Gaps = 10/151 (6%)
Frame = +3
Query: 93 CENATSLSLMIDSLLATYDRESPPDSKIVVNLTLHL-----RHANIRESESTVRILADLQ 257
C + + L + Y++ P + +T+H + AN+ E + L+
Sbjct: 28 CVGCATEERLFHKLFSHYNQFIRPVENVSDPVTVHFEVAITQLANVDEVNQIMETNLWLR 87
Query: 258 MNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNX 422
W D +L W+ E+ G T V ++++W+PD+VL N A GD+ + +A + N
Sbjct: 88 HIWNDYKLRWDPMEYDGIETLRVPADKIWKPDIVLYNNA---VGDFQVEGKTKALLKYNG 144
Query: 423 SVSXIKRLDISTPISMXLXNWPNDMXTCTFQ 515
++ + M + +P D C+ +
Sbjct: 145 MITWTPPAIFKSSCPMDITFFPFDHQNCSLK 175
>U40583-1|AAA83561.1| 502|Homo sapiens alpha 7 neuronal nicotinic
acetylcholine receptor protein.
Length = 502
Score = 41.5 bits (93), Expect = 0.004
Identities = 17/41 (41%), Positives = 25/41 (60%), Gaps = 1/41 (2%)
Frame = +3
Query: 252 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA 371
LQM+W D L WN E+ G T ++W+PD++L N+A
Sbjct: 78 LQMSWTDHYLQWNVSEYPGVKTVRFPDGQIWKPDILLYNSA 118
>M83712-1|AAA58357.1| 468|Homo sapiens nicotinic receptor alpha 5
subunit protein.
Length = 468
Score = 41.5 bits (93), Expect = 0.004
Identities = 29/138 (21%), Positives = 59/138 (42%), Gaps = 6/138 (4%)
Frame = +3
Query: 120 MIDSLLATYDRESPP----DSKIVVNLTLHLRH-ANIRESESTVRILADLQMNWIDKRLS 284
++ L Y+R P + KI + L + ++ E + L+ WID +L
Sbjct: 50 LLKDLFQDYERWVRPVEHLNDKIKIKFGLAISQLVDVDEKNQLMTTNVWLKQEWIDVKLR 109
Query: 285 WNAGEWG-CSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNXSVSXIKRLDISTP 461
WN ++G V S+ W PD+VL + A + + + N +V+ + +
Sbjct: 110 WNPDDYGGIKVIRVPSDSSWTPDIVLFDNADGRFEGTSTKTVIRYNGTVTWTPPANYKSS 169
Query: 462 ISMXLXNWPNDMXTCTFQ 515
++ + +P D+ C+ +
Sbjct: 170 CTIDVTFFPFDLQNCSMK 187
>BC014456-1|AAH14456.1| 494|Homo sapiens cholinergic receptor,
nicotinic, alpha 6 protein.
Length = 494
Score = 41.5 bits (93), Expect = 0.004
Identities = 33/151 (21%), Positives = 65/151 (43%), Gaps = 10/151 (6%)
Frame = +3
Query: 93 CENATSLSLMIDSLLATYDRESPPDSKIVVNLTLHL-----RHANIRESESTVRILADLQ 257
C + + L + Y++ P + +T+H + AN+ E + L+
Sbjct: 28 CVGCATEERLFHKLFSHYNQFIRPVENVSDPVTVHFEVAITQLANVDEVNQIMETNLWLR 87
Query: 258 MNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNX 422
W D +L W+ E+ G T V ++++W+PD+VL N A GD+ + +A + N
Sbjct: 88 HIWNDYKLRWDPMEYDGIETLRVPADKIWKPDIVLYNNA---VGDFQVEGKTKALLKYNG 144
Query: 423 SVSXIKRLDISTPISMXLXNWPNDMXTCTFQ 515
++ + M + +P D C+ +
Sbjct: 145 MITWTPPAIFKSSCPMDITFFPFDHQNCSLK 175
>AJ586911-1|CAE52911.1| 502|Homo sapiens nicotinic acetylcholine
alpha-7 subunit protein.
Length = 502
Score = 41.5 bits (93), Expect = 0.004
Identities = 17/41 (41%), Positives = 25/41 (60%), Gaps = 1/41 (2%)
Frame = +3
Query: 252 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA 371
LQM+W D L WN E+ G T ++W+PD++L N+A
Sbjct: 78 LQMSWTDHYLQWNVSEYPGVKTVRFPDGQIWKPDILLYNSA 118
>AF385585-1|AAK68111.1| 502|Homo sapiens nicotinic cholinergic
receptor alpha 7 protein.
Length = 502
Score = 41.5 bits (93), Expect = 0.004
Identities = 17/41 (41%), Positives = 25/41 (60%), Gaps = 1/41 (2%)
Frame = +3
Query: 252 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA 371
LQM+W D L WN E+ G T ++W+PD++L N+A
Sbjct: 78 LQMSWTDHYLQWNVSEYPGVKTVRFPDGQIWKPDILLYNSA 118
>AB079251-1|BAC06855.1| 494|Homo sapiens Nicotinic acetylcholine
receptor alpha 6 protein.
Length = 494
Score = 41.5 bits (93), Expect = 0.004
Identities = 33/151 (21%), Positives = 65/151 (43%), Gaps = 10/151 (6%)
Frame = +3
Query: 93 CENATSLSLMIDSLLATYDRESPPDSKIVVNLTLHL-----RHANIRESESTVRILADLQ 257
C + + L + Y++ P + +T+H + AN+ E + L+
Sbjct: 28 CVGCATEERLFHKLFSHYNQFIRPVENVSDPVTVHFEVAITQLANVDEVNQIMETNLWLR 87
Query: 258 MNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNX 422
W D +L W+ E+ G T V ++++W+PD+VL N A GD+ + +A + N
Sbjct: 88 HIWNDYKLRWDPMEYDGIETLRVPADKIWKPDIVLYNNA---VGDFQVEGKTKALLKYNG 144
Query: 423 SVSXIKRLDISTPISMXLXNWPNDMXTCTFQ 515
++ + M + +P D C+ +
Sbjct: 145 MITWTPPAIFKSSCPMDITFFPFDHQNCSLK 175
>Y08421-1|CAA69698.1| 627|Homo sapiens nicotinic acetylcholine
receptor alpha4 subunit precursor protein.
Length = 627
Score = 41.1 bits (92), Expect = 0.005
Identities = 38/164 (23%), Positives = 76/164 (46%), Gaps = 8/164 (4%)
Frame = +3
Query: 48 LLPFLLTCAIASAAECEN-ATSLSLMIDSLLATYDRESPPDSKI--VVNLTLHLRHANIR 218
LL L T + +++ E A + ++ L + Y++ S P + I VV + L A +
Sbjct: 15 LLLLLGTGLLRASSHVETRAHAEERLLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLI 74
Query: 219 ESESTVRILAD---LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLL-NAAATTA 383
+ + +++ ++ W D +L W+ ++ T + + SE +WRPD+VL NA A
Sbjct: 75 DVDEKNQMMTTNVWVKQEWHDYKLRWDPADYENVTSIRIPSELIWRPDIVLYNNADGDFA 134
Query: 384 GDYALRARVSNNXSVSXIKRLDISTPISMXLXNWPNDMXTCTFQ 515
+ +A + ++ V + S+ + +P D CT +
Sbjct: 135 VTHLTKAHLFHDGRVQWTPPAIYKSSCSIDVTFFPFDQQNCTMK 178
>X89741-1|CAA61893.1| 627|Homo sapiens neuronal acetylcholine
receptor alpha-4 subunit protein.
Length = 627
Score = 41.1 bits (92), Expect = 0.005
Identities = 38/164 (23%), Positives = 76/164 (46%), Gaps = 8/164 (4%)
Frame = +3
Query: 48 LLPFLLTCAIASAAECEN-ATSLSLMIDSLLATYDRESPPDSKI--VVNLTLHLRHANIR 218
LL L T + +++ E A + ++ L + Y++ S P + I VV + L A +
Sbjct: 15 LLLLLGTGLLRASSHVETRAHAEERLLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLI 74
Query: 219 ESESTVRILAD---LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLL-NAAATTA 383
+ + +++ ++ W D +L W+ ++ T + + SE +WRPD+VL NA A
Sbjct: 75 DVDEKNQMMTTNVWVKQEWHDYKLRWDPADYENVTSIRIPSELIWRPDIVLYNNADGDFA 134
Query: 384 GDYALRARVSNNXSVSXIKRLDISTPISMXLXNWPNDMXTCTFQ 515
+ +A + ++ V + S+ + +P D CT +
Sbjct: 135 VTHLTKAHLFHDGRVQWTPPAIYKSSCSIDVTFFPFDQQNCTMK 178
>X55019-1|CAA38759.1| 517|Homo sapiens acetylcholine receptor delta
subunit protein.
Length = 517
Score = 41.1 bits (92), Expect = 0.005
Identities = 25/80 (31%), Positives = 42/80 (52%), Gaps = 6/80 (7%)
Frame = +3
Query: 144 YDRESPP----DSKIVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEWG- 305
Y++E P + + V L L L + +++E E T+ ++ W D RL WNA E+G
Sbjct: 38 YNKELRPVAHKEESVDVALALTLSNLISLKEVEETLTTNVWIEHGWTDNRLKWNAEEFGN 97
Query: 306 CSTWLVSSERLWRPDVVLLN 365
S + + +W P++VL N
Sbjct: 98 ISVLRLPPDMVWLPEIVLEN 117
>U62433-1|AAB40111.1| 627|Homo sapiens nicotinic acetylcholine
receptor alpha4 subunit precursor protein.
Length = 627
Score = 41.1 bits (92), Expect = 0.005
Identities = 38/164 (23%), Positives = 76/164 (46%), Gaps = 8/164 (4%)
Frame = +3
Query: 48 LLPFLLTCAIASAAECEN-ATSLSLMIDSLLATYDRESPPDSKI--VVNLTLHLRHANIR 218
LL L T + +++ E A + ++ L + Y++ S P + I VV + L A +
Sbjct: 15 LLLLLGTGLLRASSHVETRAHAEERLLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLI 74
Query: 219 ESESTVRILAD---LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLL-NAAATTA 383
+ + +++ ++ W D +L W+ ++ T + + SE +WRPD+VL NA A
Sbjct: 75 DVDEKNQMMTTNVWVKQEWHDYKLRWDPADYENVTSIRIPSELIWRPDIVLYNNADGDFA 134
Query: 384 GDYALRARVSNNXSVSXIKRLDISTPISMXLXNWPNDMXTCTFQ 515
+ +A + ++ V + S+ + +P D CT +
Sbjct: 135 VTHLTKAHLFHDGRVQWTPPAIYKSSCSIDVTFFPFDQQNCTMK 178
>L35901-1|AAA64743.1| 627|Homo sapiens nicotinic acetylcholine
receptor alpha 4 subunit protein.
Length = 627
Score = 41.1 bits (92), Expect = 0.005
Identities = 38/164 (23%), Positives = 76/164 (46%), Gaps = 8/164 (4%)
Frame = +3
Query: 48 LLPFLLTCAIASAAECEN-ATSLSLMIDSLLATYDRESPPDSKI--VVNLTLHLRHANIR 218
LL L T + +++ E A + ++ L + Y++ S P + I VV + L A +
Sbjct: 15 LLLLLGTGLLRASSHVETRAHAEERLLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLI 74
Query: 219 ESESTVRILAD---LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLL-NAAATTA 383
+ + +++ ++ W D +L W+ ++ T + + SE +WRPD+VL NA A
Sbjct: 75 DVDEKNQMMTTNVWVKQEWHDYKLRWDPADYENVTSIRIPSELIWRPDIVLYNNADGDFA 134
Query: 384 GDYALRARVSNNXSVSXIKRLDISTPISMXLXNWPNDMXTCTFQ 515
+ +A + ++ V + S+ + +P D CT +
Sbjct: 135 VTHLTKAHLFHDGRVQWTPPAIYKSSCSIDVTFFPFDQQNCTMK 178
>DQ093071-1|AAY88737.1| 627|Homo sapiens cholinergic receptor,
nicotinic, alpha polypeptide 4 protein.
Length = 627
Score = 41.1 bits (92), Expect = 0.005
Identities = 38/164 (23%), Positives = 76/164 (46%), Gaps = 8/164 (4%)
Frame = +3
Query: 48 LLPFLLTCAIASAAECEN-ATSLSLMIDSLLATYDRESPPDSKI--VVNLTLHLRHANIR 218
LL L T + +++ E A + ++ L + Y++ S P + I VV + L A +
Sbjct: 15 LLLLLGTGLLRASSHVETRAHAEERLLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLI 74
Query: 219 ESESTVRILAD---LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLL-NAAATTA 383
+ + +++ ++ W D +L W+ ++ T + + SE +WRPD+VL NA A
Sbjct: 75 DVDEKNQMMTTNVWVKQEWHDYKLRWDPADYENVTSIRIPSELIWRPDIVLYNNADGDFA 134
Query: 384 GDYALRARVSNNXSVSXIKRLDISTPISMXLXNWPNDMXTCTFQ 515
+ +A + ++ V + S+ + +P D CT +
Sbjct: 135 VTHLTKAHLFHDGRVQWTPPAIYKSSCSIDVTFFPFDQQNCTMK 178
>BC131799-1|AAI31800.1| 447|Homo sapiens 5-hydroxytryptamine
(serotonin) receptor 3, family member C protein.
Length = 447
Score = 41.1 bits (92), Expect = 0.005
Identities = 20/88 (22%), Positives = 42/88 (47%), Gaps = 1/88 (1%)
Frame = +3
Query: 252 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNXSV 428
+ + W + ++WN E G + V +E LW PD+ ++ + L A +S+ +
Sbjct: 91 MDLVWDNPFINWNPKECVGINKLTVLAENLWLPDIFIVESMDVDQTPSGLTAYISSEGRI 150
Query: 429 SXIKRLDISTPISMXLXNWPNDMXTCTF 512
K + +++ ++ + +P D CTF
Sbjct: 151 KYDKPMRVTSICNLDIFYFPFDQQNCTF 178
>BC096290-1|AAH96290.1| 627|Homo sapiens cholinergic receptor,
nicotinic, alpha 4 protein.
Length = 627
Score = 41.1 bits (92), Expect = 0.005
Identities = 38/164 (23%), Positives = 76/164 (46%), Gaps = 8/164 (4%)
Frame = +3
Query: 48 LLPFLLTCAIASAAECEN-ATSLSLMIDSLLATYDRESPPDSKI--VVNLTLHLRHANIR 218
LL L T + +++ E A + ++ L + Y++ S P + I VV + L A +
Sbjct: 15 LLLLLGTGLLRASSHVETRAHAEERLLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLI 74
Query: 219 ESESTVRILAD---LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLL-NAAATTA 383
+ + +++ ++ W D +L W+ ++ T + + SE +WRPD+VL NA A
Sbjct: 75 DVDEKNQMMTTNVWVKQEWHDYKLRWDPADYENVTSIRIPSELIWRPDIVLYNNADGDFA 134
Query: 384 GDYALRARVSNNXSVSXIKRLDISTPISMXLXNWPNDMXTCTFQ 515
+ +A + ++ V + S+ + +P D CT +
Sbjct: 135 VTHLTKAHLFHDGRVQWTPPAIYKSSCSIDVTFFPFDQQNCTMK 178
>BC093925-1|AAH93925.1| 517|Homo sapiens cholinergic receptor,
nicotinic, delta protein.
Length = 517
Score = 41.1 bits (92), Expect = 0.005
Identities = 25/80 (31%), Positives = 42/80 (52%), Gaps = 6/80 (7%)
Frame = +3
Query: 144 YDRESPP----DSKIVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEWG- 305
Y++E P + + V L L L + +++E E T+ ++ W D RL WNA E+G
Sbjct: 38 YNKELRPVAHKEESVDVALALTLSNLISLKEVEETLTTNVWIEHGWTDNRLKWNAEEFGN 97
Query: 306 CSTWLVSSERLWRPDVVLLN 365
S + + +W P++VL N
Sbjct: 98 ISVLRLPPDMVWLPEIVLEN 117
>BC093923-1|AAH93923.1| 517|Homo sapiens cholinergic receptor,
nicotinic, delta protein.
Length = 517
Score = 41.1 bits (92), Expect = 0.005
Identities = 25/80 (31%), Positives = 42/80 (52%), Gaps = 6/80 (7%)
Frame = +3
Query: 144 YDRESPP----DSKIVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEWG- 305
Y++E P + + V L L L + +++E E T+ ++ W D RL WNA E+G
Sbjct: 38 YNKELRPVAHKEESVDVALALTLSNLISLKEVEETLTTNVWIEHGWTDNRLKWNAEEFGN 97
Query: 306 CSTWLVSSERLWRPDVVLLN 365
S + + +W P++VL N
Sbjct: 98 ISVLRLPPDMVWLPEIVLEN 117
>AJ295237-1|CAC16144.1| 450|Homo sapiens neuronal nicotinic
acetylcholine receptor subunit4 protein.
Length = 450
Score = 41.1 bits (92), Expect = 0.005
Identities = 34/115 (29%), Positives = 52/115 (45%), Gaps = 6/115 (5%)
Frame = +3
Query: 45 ILLPFLLTCAIASAAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHANIR 218
+LL FLL A E +L L D L A Y P D+ +N+TL + + I
Sbjct: 12 LLLLFLLPAECLGA---EGRLALKLFRD-LFANYTSALRPVADTDQTLNVTLEVTLSQII 67
Query: 219 ESESTVRILAD---LQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLLNAA 371
+ + ++L ++ W D L W+ +G + S +WRPD+VL N A
Sbjct: 68 DMDERNQVLTLYLWIRQEWTDAYLRWDPNAYGGLDAIRIPSSLVWRPDIVLYNKA 122
>AJ278118-1|CAC20435.1| 450|Homo sapiens neuronal nicotinic
acetylcholine alpha10 subunit protein.
Length = 450
Score = 41.1 bits (92), Expect = 0.005
Identities = 34/115 (29%), Positives = 52/115 (45%), Gaps = 6/115 (5%)
Frame = +3
Query: 45 ILLPFLLTCAIASAAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHANIR 218
+LL FLL A E +L L D L A Y P D+ +N+TL + + I
Sbjct: 12 LLLLFLLPAECLGA---EGRLALKLFRD-LFANYTSALRPVADTDQTLNVTLEVTLSQII 67
Query: 219 ESESTVRILAD---LQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLLNAA 371
+ + ++L ++ W D L W+ +G + S +WRPD+VL N A
Sbjct: 68 DMDERNQVLTLYLWIRQEWTDAYLRWDPNAYGGLDAIRIPSSLVWRPDIVLYNKA 122
>AF327367-1|AAK14333.1| 450|Homo sapiens nicotinic acetylcholine
receptor subunit alpha 10 protein.
Length = 450
Score = 41.1 bits (92), Expect = 0.005
Identities = 34/115 (29%), Positives = 52/115 (45%), Gaps = 6/115 (5%)
Frame = +3
Query: 45 ILLPFLLTCAIASAAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHANIR 218
+LL FLL A E +L L D L A Y P D+ +N+TL + + I
Sbjct: 12 LLLLFLLPAECLGA---EGRLALKLFRD-LFANYTSALRPVADTDQTLNVTLEVTLSQII 67
Query: 219 ESESTVRILAD---LQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLLNAA 371
+ + ++L ++ W D L W+ +G + S +WRPD+VL N A
Sbjct: 68 DMDERNQVLTLYLWIRQEWTDAYLRWDPNAYGGLDAIRIPSSLVWRPDIVLYNKA 122
>AF199235-1|AAG00795.2| 450|Homo sapiens nicotinic acetylcholine
receptor subunit alpha 10 protein.
Length = 450
Score = 41.1 bits (92), Expect = 0.005
Identities = 34/115 (29%), Positives = 52/115 (45%), Gaps = 6/115 (5%)
Frame = +3
Query: 45 ILLPFLLTCAIASAAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHANIR 218
+LL FLL A E +L L D L A Y P D+ +N+TL + + I
Sbjct: 12 LLLLFLLPAECLGA---EGRLALKLFRD-LFANYTSALRPVADTDQTLNVTLEVTLSQII 67
Query: 219 ESESTVRILAD---LQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLLNAA 371
+ + ++L ++ W D L W+ +G + S +WRPD+VL N A
Sbjct: 68 DMDERNQVLTLYLWIRQEWTDAYLRWDPNAYGGLDAIRIPSSLVWRPDIVLYNKA 122
>AC092165-2|AAY24102.1| 517|Homo sapiens unknown protein.
Length = 517
Score = 41.1 bits (92), Expect = 0.005
Identities = 25/80 (31%), Positives = 42/80 (52%), Gaps = 6/80 (7%)
Frame = +3
Query: 144 YDRESPP----DSKIVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEWG- 305
Y++E P + + V L L L + +++E E T+ ++ W D RL WNA E+G
Sbjct: 38 YNKELRPVAHKEESVDVALALTLSNLISLKEVEETLTTNVWIEHGWTDNRLKWNAEEFGN 97
Query: 306 CSTWLVSSERLWRPDVVLLN 365
S + + +W P++VL N
Sbjct: 98 ISVLRLPPDMVWLPEIVLEN 117
>X87629-1|CAA60959.1| 602|Homo sapiens nicotinic acetylcholine
receptor protein.
Length = 602
Score = 40.7 bits (91), Expect = 0.006
Identities = 32/139 (23%), Positives = 65/139 (46%), Gaps = 7/139 (5%)
Frame = +3
Query: 120 MIDSLLATYDRESPPDSKI--VVNLTLHLRHANIRESESTVRILAD---LQMNWIDKRLS 284
++ L + Y++ S P + I VV + L A + + + +++ ++ W D +L
Sbjct: 15 LLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLR 74
Query: 285 WNAGEWGCSTWL-VSSERLWRPDVVLL-NAAATTAGDYALRARVSNNXSVSXIKRLDIST 458
W+ ++ T + + SE +WRPD+VL NA A + +A + ++ V +
Sbjct: 75 WDPADYENVTSIRIPSELIWRPDIVLYNNADGDFAVTHLTKAHLFHDGRVQWTPPAIYKS 134
Query: 459 PISMXLXNWPNDMXTCTFQ 515
S+ + +P D CT +
Sbjct: 135 SCSIDVTFFPFDQQNCTMK 153
>BC109211-1|AAI09212.1| 632|Homo sapiens gamma-aminobutyric acid
(GABA) receptor, theta protein.
Length = 632
Score = 40.7 bits (91), Expect = 0.006
Identities = 34/149 (22%), Positives = 58/149 (38%), Gaps = 7/149 (4%)
Frame = +3
Query: 93 CENATSLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESESTVRILADLQM 260
C N + ++D +L+ YD P+ + + V +++++ I E I
Sbjct: 53 CANEAVVQKILDRVLSRYDVRLRPNFGGAPVPVRISIYVTSIEQISEMNMDYTITMFFHQ 112
Query: 261 NWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSN---NXSVS 431
W D RL++ + E+LW PD LN+ D + RV + +V
Sbjct: 113 TWKDSRLAYYETTLNLTLDYRMHEKLWVPDCYFLNSKDAFVHDVTVENRVFQLHPDGTVR 172
Query: 432 XIKRLDISTPISMXLXNWPNDMXTCTFQV 518
RL + S+ L +P D C V
Sbjct: 173 YGIRLTTTAACSLDLHKFPMDKQACNLVV 201
>BC109210-1|AAI09211.1| 632|Homo sapiens gamma-aminobutyric acid
(GABA) receptor, theta protein.
Length = 632
Score = 40.7 bits (91), Expect = 0.006
Identities = 34/149 (22%), Positives = 58/149 (38%), Gaps = 7/149 (4%)
Frame = +3
Query: 93 CENATSLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESESTVRILADLQM 260
C N + ++D +L+ YD P+ + + V +++++ I E I
Sbjct: 53 CANEAVVQKILDRVLSRYDVRLRPNFGGAPVPVRISIYVTSIEQISEMNMDYTITMFFHQ 112
Query: 261 NWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSN---NXSVS 431
W D RL++ + E+LW PD LN+ D + RV + +V
Sbjct: 113 TWKDSRLAYYETTLNLTLDYRMHEKLWVPDCYFLNSKDAFVHDVTVENRVFQLHPDGTVR 172
Query: 432 XIKRLDISTPISMXLXNWPNDMXTCTFQV 518
RL + S+ L +P D C V
Sbjct: 173 YGIRLTTTAACSLDLHKFPMDKQACNLVV 201
>AY349353-1|AAQ93477.1| 456|Homo sapiens 5-HT3c1 serotonin
receptor-like protein protein.
Length = 456
Score = 40.7 bits (91), Expect = 0.006
Identities = 22/89 (24%), Positives = 41/89 (46%), Gaps = 1/89 (1%)
Frame = +3
Query: 246 ADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNX 422
A L + W + +SWN E G + ++++ LW PD+ ++ L A VSN
Sbjct: 89 AILDVVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEG 148
Query: 423 SVSXIKRLDISTPISMXLXNWPNDMXTCT 509
+ K + + + ++ + +P D CT
Sbjct: 149 RIRYKKPMKVDSICNLDIFYFPFDQQNCT 177
>AY349352-1|AAQ93476.1| 441|Homo sapiens 5-HT3c1 serotonin
receptor-like protein protein.
Length = 441
Score = 40.7 bits (91), Expect = 0.006
Identities = 22/89 (24%), Positives = 41/89 (46%), Gaps = 1/89 (1%)
Frame = +3
Query: 246 ADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNX 422
A L + W + +SWN E G + ++++ LW PD+ ++ L A VSN
Sbjct: 74 AILDVVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEG 133
Query: 423 SVSXIKRLDISTPISMXLXNWPNDMXTCT 509
+ K + + + ++ + +P D CT
Sbjct: 134 RIRYKKPMKVDSICNLDIFYFPFDQQNCT 162
>AF459285-1|AAL66182.1| 447|Homo sapiens 5-hydroxytryptamine
receptor 3 subunit C protein.
Length = 447
Score = 40.7 bits (91), Expect = 0.006
Identities = 20/88 (22%), Positives = 41/88 (46%), Gaps = 1/88 (1%)
Frame = +3
Query: 252 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNXSV 428
+ + W + ++WN E G + V +E LW PD+ ++ + L A +S+ +
Sbjct: 91 MDLVWDNPFINWNPKECVGINKLTVLAENLWLPDIFIVESMDVDQTPSGLTAYISSEGRI 150
Query: 429 SXIKRLDISTPISMXLXNWPNDMXTCTF 512
K + +++ + + +P D CTF
Sbjct: 151 KYDKPMRVTSICKLDIFYFPFDQQNCTF 178
>AF189259-1|AAF70380.1| 632|Homo sapiens GABA-A receptor theta
subunit protein.
Length = 632
Score = 40.7 bits (91), Expect = 0.006
Identities = 34/149 (22%), Positives = 58/149 (38%), Gaps = 7/149 (4%)
Frame = +3
Query: 93 CENATSLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESESTVRILADLQM 260
C N + ++D +L+ YD P+ + + V +++++ I E I
Sbjct: 53 CANEAVVQKILDRVLSRYDVRLRPNFGGAPVPVRISIYVTSIEQISEMNMDYTITMFFHQ 112
Query: 261 NWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSN---NXSVS 431
W D RL++ + E+LW PD LN+ D + RV + +V
Sbjct: 113 TWKDSRLAYYETTLNLTLDYRMHEKLWVPDCYFLNSKDAFVHDVTVENRVFQLHPDGTVR 172
Query: 432 XIKRLDISTPISMXLXNWPNDMXTCTFQV 518
RL + S+ L +P D C V
Sbjct: 173 YGIRLTTTAACSLDLHKFPMDKQACNLVV 201
>AF144648-1|AAD51172.1| 627|Homo sapiens GABA-A receptor theta
protein.
Length = 627
Score = 40.7 bits (91), Expect = 0.006
Identities = 34/149 (22%), Positives = 58/149 (38%), Gaps = 7/149 (4%)
Frame = +3
Query: 93 CENATSLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESESTVRILADLQM 260
C N + ++D +L+ YD P+ + + V +++++ I E I
Sbjct: 48 CANEAVVQKILDRVLSRYDVRLRPNFGGAPVPVRISIYVTSIEQISEMNMDYTITMFFHQ 107
Query: 261 NWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSN---NXSVS 431
W D RL++ + E+LW PD LN+ D + RV + +V
Sbjct: 108 TWKDSRLAYYETTLNLTLDYRMHEKLWVPDCYFLNSKDAFVHDVTVENRVFQLHPDGTVR 167
Query: 432 XIKRLDISTPISMXLXNWPNDMXTCTFQV 518
RL + S+ L +P D C V
Sbjct: 168 YGIRLTTTAACSLDLHKFPMDKQACNLVV 196
>AJ001935-1|CAA05108.1| 504|Homo sapiens CHRNB2 protein.
Length = 504
Score = 40.3 bits (90), Expect = 0.009
Identities = 42/165 (25%), Positives = 68/165 (41%), Gaps = 6/165 (3%)
Frame = +3
Query: 45 ILLPF--LLTCAIASAAECENATSLSLMIDSLLATYDRESPPDSKIV-VNLTLHLRHA-N 212
+LL F L C+ A+ E L+ S R + S++V V L + L +
Sbjct: 10 LLLGFGLLRLCSGVWGADTEERLVEHLLDPSRYNKLIRPATNGSELVTVQLMVSLAQLIS 69
Query: 213 IRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLL-NAAATTAG 386
+ E E + L W D RL+W E+ + S+ +W PDVVL NA
Sbjct: 70 VHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLPDVVLYNNADGMYEV 129
Query: 387 DYALRARVSNNXSVSXIKRLDISTPISMXLXNWPNDMXTCTFQVR 521
+ A VS + S+ + + + + ++P D CT + R
Sbjct: 130 SFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFR 174
>Y08415-1|CAA69692.1| 502|Homo sapiens nicotinic acetylcholine
receptor beta2 subunit precursor protein.
Length = 502
Score = 39.9 bits (89), Expect = 0.011
Identities = 30/119 (25%), Positives = 50/119 (42%), Gaps = 3/119 (2%)
Frame = +3
Query: 174 IVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 347
+ V L + L ++ E E + L W D RL+W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 348 DVVLL-NAAATTAGDYALRARVSNNXSVSXIKRLDISTPISMXLXNWPNDMXTCTFQVR 521
DVVL NA + A VS + S+ + + + + ++P D CT + R
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFR 174
>X53179-1|CAA37320.1| 502|Homo sapiens precursor peptide (AA -25 to
477) protein.
Length = 502
Score = 39.9 bits (89), Expect = 0.011
Identities = 30/119 (25%), Positives = 50/119 (42%), Gaps = 3/119 (2%)
Frame = +3
Query: 174 IVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 347
+ V L + L ++ E E + L W D RL+W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 348 DVVLL-NAAATTAGDYALRARVSNNXSVSXIKRLDISTPISMXLXNWPNDMXTCTFQVR 521
DVVL NA + A VS + S+ + + + + ++P D CT + R
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFR 174
>U62437-1|AAB40115.1| 502|Homo sapiens nicotinic acetylcholine
receptor beta2 subunit precursor protein.
Length = 502
Score = 39.9 bits (89), Expect = 0.011
Identities = 30/119 (25%), Positives = 50/119 (42%), Gaps = 3/119 (2%)
Frame = +3
Query: 174 IVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 347
+ V L + L ++ E E + L W D RL+W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 348 DVVLL-NAAATTAGDYALRARVSNNXSVSXIKRLDISTPISMXLXNWPNDMXTCTFQVR 521
DVVL NA + A VS + S+ + + + + ++P D CT + R
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFR 174
>BC075041-1|AAH75041.1| 502|Homo sapiens cholinergic receptor,
nicotinic, beta 2 (neuronal) protein.
Length = 502
Score = 39.9 bits (89), Expect = 0.011
Identities = 30/119 (25%), Positives = 50/119 (42%), Gaps = 3/119 (2%)
Frame = +3
Query: 174 IVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 347
+ V L + L ++ E E + L W D RL+W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 348 DVVLL-NAAATTAGDYALRARVSNNXSVSXIKRLDISTPISMXLXNWPNDMXTCTFQVR 521
DVVL NA + A VS + S+ + + + + ++P D CT + R
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFR 174
>BC075040-1|AAH75040.1| 502|Homo sapiens cholinergic receptor,
nicotinic, beta 2 (neuronal) protein.
Length = 502
Score = 39.9 bits (89), Expect = 0.011
Identities = 30/119 (25%), Positives = 50/119 (42%), Gaps = 3/119 (2%)
Frame = +3
Query: 174 IVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 347
+ V L + L ++ E E + L W D RL+W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 348 DVVLL-NAAATTAGDYALRARVSNNXSVSXIKRLDISTPISMXLXNWPNDMXTCTFQVR 521
DVVL NA + A VS + S+ + + + + ++P D CT + R
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFR 174
>AL592078-3|CAI16184.1| 502|Homo sapiens cholinergic receptor,
nicotinic, beta 2 (neuronal) protein.
Length = 502
Score = 39.9 bits (89), Expect = 0.011
Identities = 30/119 (25%), Positives = 50/119 (42%), Gaps = 3/119 (2%)
Frame = +3
Query: 174 IVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 347
+ V L + L ++ E E + L W D RL+W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 348 DVVLL-NAAATTAGDYALRARVSNNXSVSXIKRLDISTPISMXLXNWPNDMXTCTFQVR 521
DVVL NA + A VS + S+ + + + + ++P D CT + R
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFR 174
>AF077186-1|AAD45422.1| 502|Homo sapiens neuronal nicotinic
acetylcholine receptor beta 2 protein.
Length = 502
Score = 39.9 bits (89), Expect = 0.011
Identities = 30/119 (25%), Positives = 50/119 (42%), Gaps = 3/119 (2%)
Frame = +3
Query: 174 IVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 347
+ V L + L ++ E E + L W D RL+W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 348 DVVLL-NAAATTAGDYALRARVSNNXSVSXIKRLDISTPISMXLXNWPNDMXTCTFQVR 521
DVVL NA + A VS + S+ + + + + ++P D CT + R
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFR 174
>U93917-1|AAC39917.1| 449|Homo sapiens glycine receptor alpha 3
subunit protein.
Length = 449
Score = 39.1 bits (87), Expect = 0.020
Identities = 42/169 (24%), Positives = 69/169 (40%), Gaps = 11/169 (6%)
Frame = +3
Query: 45 ILLPFLLTCAIASAAECENATSLSLMIDSLLAT---YDRESPPDSK-IVVNLTLHL---R 203
+LL + T SA S S +D L+ YD P+ K VN+T ++
Sbjct: 21 LLLSLVATKETDSARSRSAPMSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINS 80
Query: 204 HANIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERLWRPDVVLLNAAATT 380
+I E+ R+ L+ W D RL+++ S + +W+PD+ N
Sbjct: 81 FGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGAN 140
Query: 381 AGDYALR---ARVSNNXSVSXIKRLDISTPISMXLXNWPNDMXTCTFQV 518
+ R+ N +V RL ++ M L N+P D+ TC Q+
Sbjct: 141 FHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFPMDVQTCIMQL 189
>BC114947-1|AAI14948.1| 457|Homo sapiens GLRA1 protein protein.
Length = 457
Score = 39.1 bits (87), Expect = 0.020
Identities = 43/183 (23%), Positives = 78/183 (42%), Gaps = 17/183 (9%)
Frame = +3
Query: 21 HKMSTTYIILLPFLLTCAIASAAECENATSL------SLMIDSLLAT---YDRESPPDSK 173
+ +T + L ++ ++A++ E E A S S +D L+ YD P+ K
Sbjct: 2 YSFNTLRLYLWETIVFFSLAASKEAEAARSAPKPMSPSDFLDKLMGRTSGYDARIRPNFK 61
Query: 174 -IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERL 338
VN++ ++ +I E+ R+ L+ W D RL++N S + +
Sbjct: 62 GPPVNVSCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYNEYPDDSLDLDPSMLDSI 121
Query: 339 WRPDVVLLNAAATTAGDYALR---ARVSNNXSVSXIKRLDISTPISMXLXNWPNDMXTCT 509
W+PD+ N + R+S N +V R+ ++ M L N+P D+ TC
Sbjct: 122 WKPDLFFANEKGAHFHEITTDNKLLRISRNGNVLYSIRITLTLACPMDLKNFPMDVQTCI 181
Query: 510 FQV 518
Q+
Sbjct: 182 MQL 184
>BC074980-1|AAH74980.1| 449|Homo sapiens glycine receptor, alpha 1
(startle disease/hyperekplexia) protein.
Length = 449
Score = 39.1 bits (87), Expect = 0.020
Identities = 43/183 (23%), Positives = 78/183 (42%), Gaps = 17/183 (9%)
Frame = +3
Query: 21 HKMSTTYIILLPFLLTCAIASAAECENATSL------SLMIDSLLAT---YDRESPPDSK 173
+ +T + L ++ ++A++ E E A S S +D L+ YD P+ K
Sbjct: 2 YSFNTLRLYLWETIVFFSLAASKEAEAARSAPKPMSPSDFLDKLMGRTSGYDARIRPNFK 61
Query: 174 -IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERL 338
VN++ ++ +I E+ R+ L+ W D RL++N S + +
Sbjct: 62 GPPVNVSCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYNEYPDDSLDLDPSMLDSI 121
Query: 339 WRPDVVLLNAAATTAGDYALR---ARVSNNXSVSXIKRLDISTPISMXLXNWPNDMXTCT 509
W+PD+ N + R+S N +V R+ ++ M L N+P D+ TC
Sbjct: 122 WKPDLFFANEKGAHFHEITTDNKLLRISRNGNVLYSIRITLTLACPMDLKNFPMDVQTCI 181
Query: 510 FQV 518
Q+
Sbjct: 182 MQL 184
>BC036086-1|AAH36086.1| 464|Homo sapiens glycine receptor, alpha 3
protein.
Length = 464
Score = 39.1 bits (87), Expect = 0.020
Identities = 42/169 (24%), Positives = 69/169 (40%), Gaps = 11/169 (6%)
Frame = +3
Query: 45 ILLPFLLTCAIASAAECENATSLSLMIDSLLAT---YDRESPPDSK-IVVNLTLHL---R 203
+LL + T SA S S +D L+ YD P+ K VN+T ++
Sbjct: 21 LLLSLVATKETDSARSRSAPMSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINS 80
Query: 204 HANIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERLWRPDVVLLNAAATT 380
+I E+ R+ L+ W D RL+++ S + +W+PD+ N
Sbjct: 81 FGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGAN 140
Query: 381 AGDYALR---ARVSNNXSVSXIKRLDISTPISMXLXNWPNDMXTCTFQV 518
+ R+ N +V RL ++ M L N+P D+ TC Q+
Sbjct: 141 FHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFPMDVQTCIMQL 189
>AF017724-1|AAC39919.1| 465|Homo sapiens glycine receptor alpha 3
subunit protein.
Length = 465
Score = 39.1 bits (87), Expect = 0.020
Identities = 42/169 (24%), Positives = 69/169 (40%), Gaps = 11/169 (6%)
Frame = +3
Query: 45 ILLPFLLTCAIASAAECENATSLSLMIDSLLAT---YDRESPPDSK-IVVNLTLHL---R 203
+LL + T SA S S +D L+ YD P+ K VN+T ++
Sbjct: 21 LLLSLVATKETDSARSRSAPMSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINS 80
Query: 204 HANIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERLWRPDVVLLNAAATT 380
+I E+ R+ L+ W D RL+++ S + +W+PD+ N
Sbjct: 81 FGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGAN 140
Query: 381 AGDYALR---ARVSNNXSVSXIKRLDISTPISMXLXNWPNDMXTCTFQV 518
+ R+ N +V RL ++ M L N+P D+ TC Q+
Sbjct: 141 FHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFPMDVQTCIMQL 189
>X52009-1|CAA36258.1| 449|Homo sapiens inhibitory glycine receptor
protein.
Length = 449
Score = 38.7 bits (86), Expect = 0.026
Identities = 43/183 (23%), Positives = 78/183 (42%), Gaps = 17/183 (9%)
Frame = +3
Query: 21 HKMSTTYIILLPFLLTCAIASAAECENATSL------SLMIDSLLAT---YDRESPPDSK 173
+ +T + L ++ ++A++ E E A S S +D L+ YD P+ K
Sbjct: 2 YSFNTLRLYLSGAIVFFSLAASKEAEAARSATKPMSPSDFLDKLMGRTSGYDARIRPNFK 61
Query: 174 -IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERL 338
VN++ ++ +I E+ R+ L+ W D RL++N S + +
Sbjct: 62 GPPVNVSCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYNEYPDDSLDLDPSMLDSI 121
Query: 339 WRPDVVLLNAAATTAGDYALR---ARVSNNXSVSXIKRLDISTPISMXLXNWPNDMXTCT 509
W+PD+ N + R+S N +V R+ ++ M L N+P D+ TC
Sbjct: 122 WKPDLFFANEKGAHFHEITTDNKLLRISRNGNVLYSIRITLTLACPMDLKNFPMDVQTCI 181
Query: 510 FQV 518
Q+
Sbjct: 182 MQL 184
>Z93848-1|CAI41994.1| 376|Homo sapiens glycine receptor, alpha 4
protein.
Length = 376
Score = 37.5 bits (83), Expect = 0.061
Identities = 34/133 (25%), Positives = 56/133 (42%), Gaps = 8/133 (6%)
Frame = +3
Query: 144 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 311
YD P+ K VN+T ++ ++I ++ R+ L+ W D RLS+
Sbjct: 17 YDARIRPNFKGPPVNVTCNIFINSFSSITKTTMDYRVNVFLRQQWNDPRLSYREYPDDSL 76
Query: 312 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNXSVSXIKRLDISTPISMXLX 479
S + +W+PD+ N + R+ N +V RL + M L
Sbjct: 77 DLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLILSCLMDLK 136
Query: 480 NWPNDMXTCTFQV 518
N+P D+ TCT Q+
Sbjct: 137 NFPMDIQTCTMQL 149
>BC033801-1|AAH33801.1| 452|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, delta protein.
Length = 452
Score = 37.5 bits (83), Expect = 0.061
Identities = 34/135 (25%), Positives = 54/135 (40%), Gaps = 7/135 (5%)
Frame = +3
Query: 123 IDSLLATYDRESPPD-SKIVVNLTLHLRHANI---RESESTVRILADLQMNWIDKRLSWN 290
+D L+A Y R P VN+ L L A+I E+ + L +W D RLS+N
Sbjct: 44 LDGLIAGYARNFRPGIGGPPVNVALALEVASIDHISEANMEYTMTVFLHQSWRDSRLSYN 103
Query: 291 AGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNXSVSXIKRLDISTP 461
++LW PD ++NA + D + R+ + + R+ +
Sbjct: 104 HTNETLGLDSRFVDKLWLPDTFIVNAKSAWFHDVTVENKLIRLQPDGVILYSIRITSTVA 163
Query: 462 ISMXLXNWPNDMXTC 506
M L +P D C
Sbjct: 164 CDMDLAKYPMDEQEC 178
>BC022449-1|AAH22449.1| 474|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, beta 1 protein.
Length = 474
Score = 37.5 bits (83), Expect = 0.061
Identities = 36/168 (21%), Positives = 68/168 (40%), Gaps = 9/168 (5%)
Frame = +3
Query: 42 IILLPFLLT--CAIASAAECENATSLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRH 206
++ P ++T C S E N + + +D LL YD PD + V + + +
Sbjct: 12 LLSFPVMITMVCCAHSTNEPSNMSYVKETVDRLLKGYDIRLRPDFGGPPVDVGMRIDVAS 71
Query: 207 AN-IRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTA 383
+ + E + Q +W DKRLS++ + +++L PD LN +
Sbjct: 72 IDMVSEVNMDYTLTMYFQQSWKDKRLSYSGIPLNLTLDNRVADQLCVPDTYFLNDKKSFV 131
Query: 384 GDYALR---ARVSNNXSVSXIKRLDISTPISMXLXNWPNDMXTCTFQV 518
++ R+ + +V R+ + M L +P D CT ++
Sbjct: 132 HGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEI 179
>AL391845-4|CAI15436.1| 452|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, delta protein.
Length = 452
Score = 37.5 bits (83), Expect = 0.061
Identities = 34/135 (25%), Positives = 54/135 (40%), Gaps = 7/135 (5%)
Frame = +3
Query: 123 IDSLLATYDRESPPD-SKIVVNLTLHLRHANI---RESESTVRILADLQMNWIDKRLSWN 290
+D L+A Y R P VN+ L L A+I E+ + L +W D RLS+N
Sbjct: 44 LDGLIAGYARNFRPGIGGPPVNVALALEVASIDHISEANMEYTMTVFLHQSWRDSRLSYN 103
Query: 291 AGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNXSVSXIKRLDISTP 461
++LW PD ++NA + D + R+ + + R+ +
Sbjct: 104 HTNETLGLDSRFVDKLWLPDTFIVNAKSAWFHDVTVENKLIRLQPDGVILYSIRITSTVA 163
Query: 462 ISMXLXNWPNDMXTC 506
M L +P D C
Sbjct: 164 CDMDLAKYPMDEQEC 178
>AL049610-1|CAI42158.1| 376|Homo sapiens glycine receptor, alpha 4
protein.
Length = 376
Score = 37.5 bits (83), Expect = 0.061
Identities = 34/133 (25%), Positives = 56/133 (42%), Gaps = 8/133 (6%)
Frame = +3
Query: 144 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 311
YD P+ K VN+T ++ ++I ++ R+ L+ W D RLS+
Sbjct: 17 YDARIRPNFKGPPVNVTCNIFINSFSSITKTTMDYRVNVFLRQQWNDPRLSYREYPDDSL 76
Query: 312 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNXSVSXIKRLDISTPISMXLX 479
S + +W+PD+ N + R+ N +V RL + M L
Sbjct: 77 DLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLILSCLMDLK 136
Query: 480 NWPNDMXTCTFQV 518
N+P D+ TCT Q+
Sbjct: 137 NFPMDIQTCTMQL 149
>AF016917-1|AAB70007.1| 452|Homo sapiens GABA-A receptor delta
subunit protein.
Length = 452
Score = 37.5 bits (83), Expect = 0.061
Identities = 34/135 (25%), Positives = 54/135 (40%), Gaps = 7/135 (5%)
Frame = +3
Query: 123 IDSLLATYDRESPPD-SKIVVNLTLHLRHANI---RESESTVRILADLQMNWIDKRLSWN 290
+D L+A Y R P VN+ L L A+I E+ + L +W D RLS+N
Sbjct: 44 LDGLIAGYARNFRPGIGGPPVNVALALEVASIDHISEANMEYTMTVFLHQSWRDSRLSYN 103
Query: 291 AGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNXSVSXIKRLDISTP 461
++LW PD ++NA + D + R+ + + R+ +
Sbjct: 104 HTNETLGLDSRFVDKLWLPDTFIVNAKSAWFHDVTVENKLIRLQPDGVILYSIRITSTVA 163
Query: 462 ISMXLXNWPNDMXTC 506
M L +P D C
Sbjct: 164 CDMDLAKYPMDEQEC 178
>BC114967-1|AAI14968.1| 366|Homo sapiens GLRA1 protein protein.
Length = 366
Score = 35.5 bits (78), Expect = 0.24
Identities = 25/98 (25%), Positives = 42/98 (42%), Gaps = 4/98 (4%)
Frame = +3
Query: 237 RILADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERLWRPDVVLLNAAATTAGDYALR---A 404
R+ L+ W D RL++N S + +W+PD+ N +
Sbjct: 4 RVNIFLRQQWNDPRLAYNEYPDDSLDLDPSMLDSIWKPDLFFANEKGAHFHEITTDNKLL 63
Query: 405 RVSNNXSVSXIKRLDISTPISMXLXNWPNDMXTCTFQV 518
R+S N +V R+ ++ M L N+P D+ TC Q+
Sbjct: 64 RISRNGNVLYSIRITLTLACPMDLKNFPMDVQTCIMQL 101
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 109,516,507
Number of Sequences: 237096
Number of extensions: 2203055
Number of successful extensions: 5718
Number of sequences better than 10.0: 135
Number of HSP's better than 10.0 without gapping: 5380
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5647
length of database: 76,859,062
effective HSP length: 89
effective length of database: 55,757,518
effective search space used: 10705443456
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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