Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BmNP02_FL5_P14
(874 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
AJ306454-1|CAC34819.1| 497|Homo sapiens neuronal nicotinic acet... 69 2e-11
Y08416-1|CAA69693.1| 498|Homo sapiens nicotinic acetylcholine r... 67 9e-11
U62439-1|AAB40117.1| 498|Homo sapiens nicotinic acetylcholine r... 67 9e-11
U48861-1|AAA92123.1| 498|Homo sapiens beta 4 nicotinic acetylch... 67 9e-11
BC096082-1|AAH96082.1| 498|Homo sapiens cholinergic receptor, n... 67 9e-11
BC096080-1|AAH96080.1| 498|Homo sapiens cholinergic receptor, n... 67 9e-11
AF306329-1|AAL02062.1| 498|Homo sapiens neuronal nicotinic acet... 67 9e-11
Y08417-1|CAA69694.1| 458|Homo sapiens nicotinic acetylcholine r... 64 5e-10
X67513-1|CAA47851.1| 423|Homo sapiens nicotinic acetylcholine ... 64 5e-10
U62438-1|AAB40116.1| 458|Homo sapiens nicotinic acetylcholine r... 64 5e-10
BC069788-1|AAH69788.1| 458|Homo sapiens cholinergic receptor, n... 64 5e-10
BC069703-1|AAH69703.1| 458|Homo sapiens cholinergic receptor, n... 64 5e-10
BC069681-1|AAH69681.1| 458|Homo sapiens cholinergic receptor, n... 64 5e-10
AF140765-1|AAD33063.1| 458|Homo sapiens neuronal acetylcholine ... 64 5e-10
X68275-1|CAA48336.1| 451|Homo sapiens nicotinic receptor beta 4... 63 1e-09
Y16281-1|CAA76154.1| 529|Homo sapiens nicotinic acetylcholine r... 62 2e-09
U62431-1|AAB40109.1| 529|Homo sapiens nicotinic acetylcholine r... 62 2e-09
Y08419-1|CAA69696.1| 468|Homo sapiens nicotinic acetylcholine r... 62 3e-09
Y08418-1|CAA69695.1| 503|Homo sapiens nicotinic acetylcholine r... 62 3e-09
X53559-1|CAA37625.1| 474|Homo sapiens neuronal nicotinic acetyl... 62 3e-09
U62434-1|AAB40112.1| 468|Homo sapiens nicotinic acetylcholine r... 62 3e-09
U62432-1|AAB40110.1| 504|Homo sapiens nicotinic acetylcholine r... 62 3e-09
M37981-1|AAA59942.1| 503|Homo sapiens neuronal nicotinic acetyl... 62 3e-09
BT006897-1|AAP35543.1| 505|Homo sapiens cholinergic receptor, n... 62 3e-09
BT006646-1|AAP35292.1| 489|Homo sapiens cholinergic receptor, n... 62 3e-09
BC098443-1|AAH98443.1| 504|Homo sapiens cholinergic receptor, n... 62 3e-09
BC033639-1|AAH33639.1| 468|Homo sapiens cholinergic receptor, n... 62 3e-09
BC006114-1|AAH06114.1| 489|Homo sapiens CHRNA3 protein protein. 62 3e-09
BC002996-1|AAH02996.1| 505|Homo sapiens cholinergic receptor, n... 62 3e-09
BC001642-1|AAH01642.1| 505|Homo sapiens cholinergic receptor, n... 62 3e-09
BC000513-1|AAH00513.1| 505|Homo sapiens cholinergic receptor, n... 62 3e-09
AJ306481-1|CAC34820.1| 468|Homo sapiens neuronal nicotinic acet... 62 3e-09
AJ007783-1|CAA07682.1| 504|Homo sapiens nicotinic acetylcholine... 62 3e-09
AF385584-1|AAK68110.1| 489|Homo sapiens nicotinic cholinergic r... 62 3e-09
Y16282-1|CAA76155.1| 494|Homo sapiens nicotinic acetylcholine r... 61 4e-09
U62435-1|AAB40113.1| 494|Homo sapiens nicotinic acetylcholine r... 61 4e-09
BC014456-1|AAH14456.1| 494|Homo sapiens cholinergic receptor, n... 61 4e-09
AB079251-1|BAC06855.1| 494|Homo sapiens Nicotinic acetylcholine... 61 4e-09
M83712-1|AAA58357.1| 468|Homo sapiens nicotinic receptor alpha ... 61 6e-09
X14830-1|CAA32939.1| 501|Homo sapiens protein ( Human mRNA for ... 60 8e-09
BC011371-1|AAH11371.1| 501|Homo sapiens cholinergic receptor, n... 60 8e-09
M86383-1|AAC84176.1| 502|Homo sapiens nicotinic acetylcholine r... 60 1e-08
Y08421-1|CAA69698.1| 627|Homo sapiens nicotinic acetylcholine r... 59 2e-08
X89741-1|CAA61893.1| 627|Homo sapiens neuronal acetylcholine re... 59 2e-08
X87629-1|CAA60959.1| 602|Homo sapiens nicotinic acetylcholine r... 59 2e-08
U62433-1|AAB40111.1| 627|Homo sapiens nicotinic acetylcholine r... 59 2e-08
L35901-1|AAA64743.1| 627|Homo sapiens nicotinic acetylcholine r... 59 2e-08
DQ093071-1|AAY88737.1| 627|Homo sapiens cholinergic receptor, n... 59 2e-08
BC096290-1|AAH96290.1| 627|Homo sapiens cholinergic receptor, n... 59 2e-08
BC023553-1|AAH23553.1| 501|Homo sapiens cholinergic receptor, n... 59 2e-08
Y00762-1|CAA68731.1| 457|Homo sapiens protein ( Human mRNA for ... 59 2e-08
X02502-1|CAA26344.1| 457|Homo sapiens acetylcholine receptor pr... 59 2e-08
S77094-1|AAD14247.1| 457|Homo sapiens nicotinic acetylcholine r... 59 2e-08
BC006314-1|AAH06314.1| 269|Homo sapiens CHRNA1 protein protein. 59 2e-08
AC018890-1|AAY14687.1| 457|Homo sapiens unknown protein. 59 2e-08
Y08415-1|CAA69692.1| 502|Homo sapiens nicotinic acetylcholine r... 56 2e-07
X53179-1|CAA37320.1| 502|Homo sapiens precursor peptide (AA -25... 56 2e-07
X01715-1|CAA25861.1| 520|Homo sapiens acetylcholine receptor ga... 56 2e-07
U62437-1|AAB40115.1| 502|Homo sapiens nicotinic acetylcholine r... 56 2e-07
BC075041-1|AAH75041.1| 502|Homo sapiens cholinergic receptor, n... 56 2e-07
BC075040-1|AAH75040.1| 502|Homo sapiens cholinergic receptor, n... 56 2e-07
AL592078-3|CAI16184.1| 502|Homo sapiens cholinergic receptor, n... 56 2e-07
AJ001935-1|CAA05108.1| 504|Homo sapiens CHRNB2 protein. 56 2e-07
AF077186-1|AAD45422.1| 502|Homo sapiens neuronal nicotinic acet... 56 2e-07
AC092165-3|AAY24103.1| 520|Homo sapiens unknown protein. 56 2e-07
X55019-1|CAA38759.1| 517|Homo sapiens acetylcholine receptor de... 55 3e-07
BC093925-1|AAH93925.1| 517|Homo sapiens cholinergic receptor, n... 55 3e-07
BC093923-1|AAH93923.1| 517|Homo sapiens cholinergic receptor, n... 55 3e-07
AC092165-2|AAY24102.1| 517|Homo sapiens unknown protein. 55 3e-07
X66403-1|CAA47030.1| 493|Homo sapiens acetylcholine receptor ep... 54 5e-07
AF105999-1|AAD24503.1| 493|Homo sapiens acetylcholine receptor ... 54 5e-07
DQ644022-1|ABG35128.1| 456|Homo sapiens 5-HT3 receptor subunit ... 52 2e-06
BC101185-1|AAI01186.1| 374|Homo sapiens HTR3E protein protein. 52 2e-06
BC101183-1|AAI01184.1| 471|Homo sapiens 5-hydroxytryptamine (se... 52 2e-06
BC101182-1|AAI01183.1| 471|Homo sapiens 5-hydroxytryptamine (se... 52 2e-06
AY159813-1|AAO38167.2| 471|Homo sapiens 5-hydroxytryptamine ser... 52 2e-06
Z23141-1|CAA80672.1| 479|Homo sapiens cholinergic receptor, nic... 52 3e-06
Y08420-1|CAA69697.1| 502|Homo sapiens nicotinic acetylcholine r... 52 3e-06
X70297-1|CAA49778.1| 502|Homo sapiens neuronal nicotinic acetyl... 52 3e-06
U62436-1|AAB40114.1| 502|Homo sapiens nicotinic acetylcholine r... 52 3e-06
AJ586911-1|CAE52911.1| 502|Homo sapiens nicotinic acetylcholine... 52 3e-06
AJ295237-1|CAC16144.1| 450|Homo sapiens neuronal nicotinic acet... 52 3e-06
AJ278118-1|CAC20435.1| 450|Homo sapiens neuronal nicotinic acet... 52 3e-06
AF327367-1|AAK14333.1| 450|Homo sapiens nicotinic acetylcholine... 52 3e-06
AF199235-1|AAG00795.2| 450|Homo sapiens nicotinic acetylcholine... 52 3e-06
L08485-1|AAA58490.1| 462|Homo sapiens GABA-benzodiazepine recep... 52 4e-06
BT009830-1|AAP88832.1| 462|Homo sapiens gamma-aminobutyric acid... 52 4e-06
BC113422-1|AAI13423.1| 462|Homo sapiens gamma-aminobutyric acid... 52 4e-06
BC111979-1|AAI11980.1| 462|Homo sapiens gamma-aminobutyric acid... 52 4e-06
BC111802-1|AAI11803.1| 465|Homo sapiens CHRNG protein protein. 51 5e-06
BC131799-1|AAI31800.1| 447|Homo sapiens 5-hydroxytryptamine (se... 51 6e-06
BC113575-1|AAI13576.1| 479|Homo sapiens cholinergic receptor, n... 51 6e-06
BC113549-1|AAI13550.1| 479|Homo sapiens cholinergic receptor, n... 51 6e-06
BC110597-1|AAI10598.1| 411|Homo sapiens ligand-gated ion channe... 51 6e-06
AY349353-1|AAQ93477.1| 456|Homo sapiens 5-HT3c1 serotonin recep... 51 6e-06
AY349352-1|AAQ93476.1| 441|Homo sapiens 5-HT3c1 serotonin recep... 51 6e-06
AY123244-1|AAM74523.1| 479|Homo sapiens nicotinic acetylcholine... 51 6e-06
AK122638-1|BAC85499.1| 266|Homo sapiens yte protein of 76kDa) (... 51 6e-06
AJ243342-1|CAB65091.1| 479|Homo sapiens nicotinic acetylcholine... 51 6e-06
AF512521-1|AAO20969.1| 411|Homo sapiens ligand-gated ion channe... 51 6e-06
AF227732-1|AAF61920.1| 470|Homo sapiens nicotinic acetylcholine... 51 6e-06
AC118275-1|AAY40986.1| 479|Homo sapiens unknown protein. 51 6e-06
U40583-1|AAA83561.1| 502|Homo sapiens alpha 7 neuronal nicotini... 50 8e-06
BC028629-1|AAH28629.1| 492|Homo sapiens gamma-aminobutyric acid... 50 8e-06
AF459285-1|AAL66182.1| 447|Homo sapiens 5-hydroxytryptamine rec... 50 8e-06
AF385585-1|AAK68111.1| 502|Homo sapiens nicotinic cholinergic r... 50 8e-06
AB223030-1|BAE19924.1| 411|Homo sapiens ligand-gated ion-channe... 50 8e-06
S62908-1|AAB27279.1| 492|Homo sapiens gamma-aminobutyric acidA ... 50 1e-05
AF166361-1|AAG12455.1| 492|Homo sapiens GABA receptor subunit a... 50 1e-05
U77731-2|AAB38273.1| 360|Homo sapiens glycine receptor alpha 2B... 49 2e-05
CR450343-1|CAG29339.1| 452|Homo sapiens GLRA2 protein. 49 2e-05
AY437084-1|AAR87843.1| 452|Homo sapiens glycine receptor alpha2... 49 2e-05
X52008-1|CAA36257.1| 452|Homo sapiens inhibitory glycine recept... 49 3e-05
U77731-1|AAB38272.1| 360|Homo sapiens glycine receptor alpha 2 ... 49 3e-05
BC032864-1|AAH32864.1| 452|Homo sapiens glycine receptor, alpha... 49 3e-05
AY437083-1|AAR87842.1| 452|Homo sapiens glycine receptor alpha2... 49 3e-05
AF053495-1|AAC35290.1| 452|Homo sapiens glycine receptor alpha ... 49 3e-05
S81944-1|AAB36480.1| 453|Homo sapiens gamma-aminobutyric acid t... 48 4e-05
BC099641-1|AAH99641.1| 453|Homo sapiens gamma-aminobutyric acid... 48 4e-05
BC099640-1|AAH99640.1| 453|Homo sapiens gamma-aminobutyric acid... 48 4e-05
BC096242-1|AAH96242.1| 453|Homo sapiens gamma-aminobutyric acid... 48 4e-05
BC096241-1|AAH96241.1| 453|Homo sapiens gamma-aminobutyric acid... 48 4e-05
S82769-1|AAB39369.1| 467|Homo sapiens GABAA receptor gamma 3 su... 48 6e-05
BC096083-1|AAH96083.1| 198|Homo sapiens CHRNB4 protein protein. 48 6e-05
BC096081-1|AAH96081.1| 198|Homo sapiens CHRNB4 protein protein. 48 6e-05
AF269144-1|AAF99698.1| 467|Homo sapiens GABAA receptor gamma 3 ... 48 6e-05
AF228458-1|AAF63215.1| 449|Homo sapiens GABAA receptor gamma 3 ... 48 6e-05
U30461-1|AAB52519.1| 554|Homo sapiens GABAA receptor subunit al... 46 2e-04
S82612-1|AAB37533.2| 478|Homo sapiens 5-hydroxytryptamine type ... 46 2e-04
M59216-1|AAA35862.1| 474|Homo sapiens gamma-aminobutyric acid r... 46 2e-04
BC109211-1|AAI09212.1| 632|Homo sapiens gamma-aminobutyric acid... 46 2e-04
BC109210-1|AAI09211.1| 632|Homo sapiens gamma-aminobutyric acid... 46 2e-04
BC035055-1|AAH35055.1| 554|Homo sapiens gamma-aminobutyric acid... 46 2e-04
AF189259-1|AAF70380.1| 632|Homo sapiens GABA-A receptor theta s... 46 2e-04
AF144648-1|AAD51172.1| 627|Homo sapiens GABA-A receptor theta p... 46 2e-04
S77554-1|AAB33983.1| 474|Homo sapiens GABAA receptor beta 2 sub... 46 2e-04
S77553-1|AAB33982.1| 512|Homo sapiens GABAA receptor beta 2 sub... 46 2e-04
S67368-1|AAB29370.1| 474|Homo sapiens gamma-aminobutyric acid A... 46 2e-04
D49394-1|BAA08387.1| 478|Homo sapiens serotonin 5-HT3 receptor ... 46 2e-04
BT007204-1|AAP35868.1| 484|Homo sapiens 5-hydroxytryptamine (se... 46 2e-04
BC105639-1|AAI05640.1| 474|Homo sapiens GABRB2 protein protein. 46 2e-04
BC099719-1|AAH99719.1| 474|Homo sapiens GABRB2 protein protein. 46 2e-04
BC099705-1|AAH99705.1| 474|Homo sapiens GABRB2 protein protein. 46 2e-04
BC004453-1|AAH04453.2| 478|Homo sapiens 5-hydroxytryptamine (se... 46 2e-04
BC002354-1|AAH02354.1| 478|Homo sapiens 5-hydroxytryptamine (se... 46 2e-04
AJ005205-1|CAA06442.3| 478|Homo sapiens serotonin 3 receptor pr... 46 2e-04
AJ003080-1|CAA05853.1| 238|Homo sapiens serotonin receptor prot... 46 2e-04
AJ003079-1|CAA05852.1| 478|Homo sapiens 5-hydroxytryptamine3 re... 46 2e-04
AJ003078-1|CAA05851.1| 510|Homo sapiens serotonin receptor prot... 46 2e-04
AF498984-1|AAM21131.1| 478|Homo sapiens 5-hydroxytryptamine rec... 46 2e-04
X14767-1|CAA32875.1| 474|Homo sapiens GABA-A receptor beta 1 su... 45 3e-04
X52009-1|CAA36258.1| 449|Homo sapiens inhibitory glycine recept... 45 4e-04
BC114947-1|AAI14948.1| 457|Homo sapiens GLRA1 protein protein. 45 4e-04
BC074980-1|AAH74980.1| 449|Homo sapiens glycine receptor, alpha... 45 4e-04
BC033801-1|AAH33801.1| 452|Homo sapiens gamma-aminobutyric acid... 44 5e-04
AL391845-4|CAI15436.1| 452|Homo sapiens gamma-aminobutyric acid... 44 5e-04
AF016917-1|AAB70007.1| 452|Homo sapiens GABA-A receptor delta s... 44 5e-04
Z93848-1|CAI41994.1| 376|Homo sapiens glycine receptor, alpha 4... 44 0.001
AL049610-1|CAI42158.1| 376|Homo sapiens glycine receptor, alpha... 44 0.001
U95367-1|AAC51357.1| 440|Homo sapiens GABA-A receptor pi subuni... 43 0.001
BC109106-1|AAI09107.1| 440|Homo sapiens gamma-aminobutyric acid... 43 0.001
BC109105-1|AAI09106.1| 440|Homo sapiens gamma-aminobutyric acid... 43 0.001
BC074865-1|AAH74865.1| 440|Homo sapiens gamma-aminobutyric acid... 43 0.001
BC074810-1|AAH74810.1| 440|Homo sapiens gamma-aminobutyric acid... 43 0.001
AF009702-1|AAC24194.1| 440|Homo sapiens GABA-A receptor pi subu... 43 0.001
U93917-1|AAC39917.1| 449|Homo sapiens glycine receptor alpha 3 ... 43 0.002
BC074795-1|AAH74795.1| 467|Homo sapiens gamma-aminobutyric acid... 43 0.002
BC069348-1|AAH69348.1| 467|Homo sapiens gamma-aminobutyric acid... 43 0.002
BC059389-1|AAH59389.1| 475|Homo sapiens gamma-aminobutyric acid... 43 0.002
BC036086-1|AAH36086.1| 464|Homo sapiens glycine receptor, alpha... 43 0.002
AF165124-1|AAD50273.1| 467|Homo sapiens gamma-aminobutyric acid... 43 0.002
AF017724-1|AAC39919.1| 465|Homo sapiens glycine receptor alpha ... 43 0.002
BC114967-1|AAI14968.1| 366|Homo sapiens GLRA1 protein protein. 42 0.002
X15376-1|CAA33437.1| 467|Homo sapiens GABA-A receptor gamma 2 s... 42 0.004
BC031087-1|AAH31087.1| 465|Homo sapiens gamma-aminobutyric acid... 42 0.004
BC022449-1|AAH22449.1| 474|Homo sapiens gamma-aminobutyric acid... 41 0.007
AB046822-1|BAB13428.1| 1003|Homo sapiens KIAA1602 protein protein. 35 0.44
AB209359-1|BAD92596.1| 533|Homo sapiens cholinergic receptor, n... 34 0.58
BC096291-1|AAH96291.1| 556|Homo sapiens CHRNA4 protein protein. 33 1.0
BC044636-1|AAH44636.1| 520|Homo sapiens YLPM1 protein protein. 33 1.4
AK091050-1|BAC03574.1| 723|Homo sapiens protein ( Homo sapiens ... 33 1.4
AK090435-1|BAC03416.1| 1766|Homo sapiens FLJ00353 protein protein. 33 1.4
U83981-1|AAC25631.1| 674|Homo sapiens apoptosis associated prot... 31 5.5
CR457259-1|CAG33540.1| 674|Homo sapiens PPP1R15A protein. 31 5.5
BC003067-1|AAH03067.1| 674|Homo sapiens protein phosphatase 1, ... 31 5.5
AK001361-1|BAA91649.1| 674|Homo sapiens protein ( Homo sapiens ... 31 5.5
BC146774-1|AAI46775.1| 1114|Homo sapiens GPR124 protein protein. 31 7.2
AY181242-1|AAO27354.1| 1331|Homo sapiens G protein-coupled recep... 31 7.2
AK074099-1|BAB84925.1| 1310|Homo sapiens FLJ00170 protein protein. 31 7.2
AF378755-1|AAL11992.1| 1331|Homo sapiens tumor endothelial marke... 31 7.2
AB040964-1|BAA96055.2| 1206|Homo sapiens KIAA1531 protein protein. 31 7.2
AK122582-1|BAC56923.1| 1383|Homo sapiens FLJ00269 protein protein. 30 9.5
>AJ306454-1|CAC34819.1| 497|Homo sapiens neuronal nicotinic
acetylcholine receptor beta-4 subunit protein.
Length = 497
Score = 68.9 bits (161), Expect = 2e-11
Identities = 44/159 (27%), Positives = 74/159 (46%), Gaps = 8/159 (5%)
Frame = +2
Query: 92 AIASAAECENATSLSLMIDSLL--ATYD---RDSPPDSKIV-VNLTLHLRHA-NIRESES 250
A+ C A + ++D LL Y+ R + S+++ + L L L ++ E E
Sbjct: 14 ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQ 73
Query: 251 TVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRAR 427
+ L+ W D RL+WN+ + G + + ++R+W PD+VL N T
Sbjct: 74 IMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNDGTYEVSVYTNLI 133
Query: 428 VSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 544
V +NGSV W+ + +++ +P D Q CT KF S
Sbjct: 134 VRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRS 172
>Y08416-1|CAA69693.1| 498|Homo sapiens nicotinic acetylcholine
receptor beta4 subunit precursor protein.
Length = 498
Score = 66.9 bits (156), Expect = 9e-11
Identities = 45/160 (28%), Positives = 75/160 (46%), Gaps = 9/160 (5%)
Frame = +2
Query: 92 AIASAAECENATSLSLMIDSLL--ATYD---RDSPPDSKIV-VNLTLHLRHA-NIRESES 250
A+ C A + ++D LL Y+ R + S+++ + L L L ++ E E
Sbjct: 14 ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQ 73
Query: 251 TVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRA 424
+ L+ W D RL+WN+ + G + + ++R+W PD+VL N A T
Sbjct: 74 IMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNADGTYEVSVYTNL 133
Query: 425 RVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 544
V +NGSV W+ + +++ +P D Q CT KF S
Sbjct: 134 IVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRS 173
>U62439-1|AAB40117.1| 498|Homo sapiens nicotinic acetylcholine
receptor beta4 subunit precursor protein.
Length = 498
Score = 66.9 bits (156), Expect = 9e-11
Identities = 45/160 (28%), Positives = 75/160 (46%), Gaps = 9/160 (5%)
Frame = +2
Query: 92 AIASAAECENATSLSLMIDSLL--ATYD---RDSPPDSKIV-VNLTLHLRHA-NIRESES 250
A+ C A + ++D LL Y+ R + S+++ + L L L ++ E E
Sbjct: 14 ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQ 73
Query: 251 TVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRA 424
+ L+ W D RL+WN+ + G + + ++R+W PD+VL N A T
Sbjct: 74 IMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNADGTYEVSVYTNL 133
Query: 425 RVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 544
V +NGSV W+ + +++ +P D Q CT KF S
Sbjct: 134 IVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRS 173
>U48861-1|AAA92123.1| 498|Homo sapiens beta 4 nicotinic
acetylcholine receptor subunit protein.
Length = 498
Score = 66.9 bits (156), Expect = 9e-11
Identities = 45/160 (28%), Positives = 75/160 (46%), Gaps = 9/160 (5%)
Frame = +2
Query: 92 AIASAAECENATSLSLMIDSLL--ATYD---RDSPPDSKIV-VNLTLHLRHA-NIRESES 250
A+ C A + ++D LL Y+ R + S+++ + L L L ++ E E
Sbjct: 14 ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQ 73
Query: 251 TVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRA 424
+ L+ W D RL+WN+ + G + + ++R+W PD+VL N A T
Sbjct: 74 IMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNADGTYEVSVYTNL 133
Query: 425 RVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 544
V +NGSV W+ + +++ +P D Q CT KF S
Sbjct: 134 IVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRS 173
>BC096082-1|AAH96082.1| 498|Homo sapiens cholinergic receptor,
nicotinic, beta 4 protein.
Length = 498
Score = 66.9 bits (156), Expect = 9e-11
Identities = 45/160 (28%), Positives = 75/160 (46%), Gaps = 9/160 (5%)
Frame = +2
Query: 92 AIASAAECENATSLSLMIDSLL--ATYD---RDSPPDSKIV-VNLTLHLRHA-NIRESES 250
A+ C A + ++D LL Y+ R + S+++ + L L L ++ E E
Sbjct: 14 ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQ 73
Query: 251 TVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRA 424
+ L+ W D RL+WN+ + G + + ++R+W PD+VL N A T
Sbjct: 74 IMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNADGTYEVSVYTNL 133
Query: 425 RVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 544
V +NGSV W+ + +++ +P D Q CT KF S
Sbjct: 134 IVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRS 173
>BC096080-1|AAH96080.1| 498|Homo sapiens cholinergic receptor,
nicotinic, beta 4 protein.
Length = 498
Score = 66.9 bits (156), Expect = 9e-11
Identities = 45/160 (28%), Positives = 75/160 (46%), Gaps = 9/160 (5%)
Frame = +2
Query: 92 AIASAAECENATSLSLMIDSLL--ATYD---RDSPPDSKIV-VNLTLHLRHA-NIRESES 250
A+ C A + ++D LL Y+ R + S+++ + L L L ++ E E
Sbjct: 14 ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQ 73
Query: 251 TVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRA 424
+ L+ W D RL+WN+ + G + + ++R+W PD+VL N A T
Sbjct: 74 IMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNADGTYEVSVYTNL 133
Query: 425 RVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 544
V +NGSV W+ + +++ +P D Q CT KF S
Sbjct: 134 IVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRS 173
>AF306329-1|AAL02062.1| 498|Homo sapiens neuronal nicotinic
acetylcholine receptor beta 4 subunit protein.
Length = 498
Score = 66.9 bits (156), Expect = 9e-11
Identities = 45/160 (28%), Positives = 75/160 (46%), Gaps = 9/160 (5%)
Frame = +2
Query: 92 AIASAAECENATSLSLMIDSLL--ATYD---RDSPPDSKIV-VNLTLHLRHA-NIRESES 250
A+ C A + ++D LL Y+ R + S+++ + L L L ++ E E
Sbjct: 14 ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQ 73
Query: 251 TVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRA 424
+ L+ W D RL+WN+ + G + + ++R+W PD+VL N A T
Sbjct: 74 IMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNADGTYEVSVYTNL 133
Query: 425 RVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 544
V +NGSV W+ + +++ +P D Q CT KF S
Sbjct: 134 IVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRS 173
>Y08417-1|CAA69694.1| 458|Homo sapiens nicotinic acetylcholine
receptor beta3 subunit precursor protein.
Length = 458
Score = 64.5 bits (150), Expect = 5e-10
Identities = 34/107 (31%), Positives = 51/107 (47%), Gaps = 2/107 (1%)
Frame = +2
Query: 230 NIRESESTVRIQADLQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLL-NAAATTA 403
++ E + L+ W D +L WN ++G + V SE LW PD+VL NA
Sbjct: 67 DVDEKNQLMTTNVWLKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFE 126
Query: 404 GDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 544
G + V +NG+V W + +M + +P D Q C+ KFGS
Sbjct: 127 GSLMTKVIVKSNGTVVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGS 173
>X67513-1|CAA47851.1| 423|Homo sapiens nicotinic acetylcholine
receptor beta-3 subunit protein.
Length = 423
Score = 64.5 bits (150), Expect = 5e-10
Identities = 34/107 (31%), Positives = 51/107 (47%), Gaps = 2/107 (1%)
Frame = +2
Query: 230 NIRESESTVRIQADLQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLL-NAAATTA 403
++ E + L+ W D +L WN ++G + V SE LW PD+VL NA
Sbjct: 32 DVDEKNQLMTTNVWLKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFE 91
Query: 404 GDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 544
G + V +NG+V W + +M + +P D Q C+ KFGS
Sbjct: 92 GSLMTKVIVKSNGTVVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGS 138
>U62438-1|AAB40116.1| 458|Homo sapiens nicotinic acetylcholine
receptor beta3 subunit precursor protein.
Length = 458
Score = 64.5 bits (150), Expect = 5e-10
Identities = 34/107 (31%), Positives = 51/107 (47%), Gaps = 2/107 (1%)
Frame = +2
Query: 230 NIRESESTVRIQADLQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLL-NAAATTA 403
++ E + L+ W D +L WN ++G + V SE LW PD+VL NA
Sbjct: 67 DVDEKNQLMTTNVWLKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFE 126
Query: 404 GDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 544
G + V +NG+V W + +M + +P D Q C+ KFGS
Sbjct: 127 GSLMTKVIVKSNGTVVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGS 173
>BC069788-1|AAH69788.1| 458|Homo sapiens cholinergic receptor,
nicotinic, beta 3 protein.
Length = 458
Score = 64.5 bits (150), Expect = 5e-10
Identities = 34/107 (31%), Positives = 51/107 (47%), Gaps = 2/107 (1%)
Frame = +2
Query: 230 NIRESESTVRIQADLQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLL-NAAATTA 403
++ E + L+ W D +L WN ++G + V SE LW PD+VL NA
Sbjct: 67 DVDEKNQLMTTNVWLKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFE 126
Query: 404 GDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 544
G + V +NG+V W + +M + +P D Q C+ KFGS
Sbjct: 127 GSLMTKVIVKSNGTVVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGS 173
>BC069703-1|AAH69703.1| 458|Homo sapiens cholinergic receptor,
nicotinic, beta 3 protein.
Length = 458
Score = 64.5 bits (150), Expect = 5e-10
Identities = 34/107 (31%), Positives = 51/107 (47%), Gaps = 2/107 (1%)
Frame = +2
Query: 230 NIRESESTVRIQADLQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLL-NAAATTA 403
++ E + L+ W D +L WN ++G + V SE LW PD+VL NA
Sbjct: 67 DVDEKNQLMTTNVWLKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFE 126
Query: 404 GDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 544
G + V +NG+V W + +M + +P D Q C+ KFGS
Sbjct: 127 GSLMTKVIVKSNGTVVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGS 173
>BC069681-1|AAH69681.1| 458|Homo sapiens cholinergic receptor,
nicotinic, beta 3 protein.
Length = 458
Score = 64.5 bits (150), Expect = 5e-10
Identities = 34/107 (31%), Positives = 51/107 (47%), Gaps = 2/107 (1%)
Frame = +2
Query: 230 NIRESESTVRIQADLQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLL-NAAATTA 403
++ E + L+ W D +L WN ++G + V SE LW PD+VL NA
Sbjct: 67 DVDEKNQLMTTNVWLKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFE 126
Query: 404 GDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 544
G + V +NG+V W + +M + +P D Q C+ KFGS
Sbjct: 127 GSLMTKVIVKSNGTVVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGS 173
>AF140765-1|AAD33063.1| 458|Homo sapiens neuronal acetylcholine
receptor beta-3 subunit precursor protein.
Length = 458
Score = 64.5 bits (150), Expect = 5e-10
Identities = 34/107 (31%), Positives = 51/107 (47%), Gaps = 2/107 (1%)
Frame = +2
Query: 230 NIRESESTVRIQADLQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLL-NAAATTA 403
++ E + L+ W D +L WN ++G + V SE LW PD+VL NA
Sbjct: 67 DVDEKNQLMTTNVWLKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFE 126
Query: 404 GDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 544
G + V +NG+V W + +M + +P D Q C+ KFGS
Sbjct: 127 GSLMTKVIVKSNGTVVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGS 173
>X68275-1|CAA48336.1| 451|Homo sapiens nicotinic receptor beta 4
subunit protein.
Length = 451
Score = 62.9 bits (146), Expect = 1e-09
Identities = 36/120 (30%), Positives = 58/120 (48%), Gaps = 3/120 (2%)
Frame = +2
Query: 194 IVVNLTLHLRHA-NIRESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 367
I + L L L ++ E + + L+ W D RL+WN+ + G + + ++R+W P
Sbjct: 7 ISIKLQLSLAQLISVNERDEIMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLP 66
Query: 368 DVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 544
D+VL N A T V +NGSV W+ + +++ +P D Q CT KF S
Sbjct: 67 DIVLYNNADGTYEVSVYTNLIVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRS 126
>Y16281-1|CAA76154.1| 529|Homo sapiens nicotinic acetylcholine
receptor alpha2 subunit precursor protein.
Length = 529
Score = 62.5 bits (145), Expect = 2e-09
Identities = 34/107 (31%), Positives = 53/107 (49%), Gaps = 2/107 (1%)
Frame = +2
Query: 230 NIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAA-ATTA 403
++ E + L+ W D +L WN ++G T L V SE +W PD+VL N A A
Sbjct: 97 DVDEKNQMMTTNVWLKQEWSDYKLRWNPADFGNITSLRVPSEMIWIPDIVLYNNADGEFA 156
Query: 404 GDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 544
+ +A + + G+V W+ + S+ + +P D Q C KFGS
Sbjct: 157 VTHMTKAHLFSTGTVHWVPPAIYKSSCSIDVTFFPFDQQNCKMKFGS 203
>U62431-1|AAB40109.1| 529|Homo sapiens nicotinic acetylcholine
receptor alpha2 subunit precursor protein.
Length = 529
Score = 62.5 bits (145), Expect = 2e-09
Identities = 34/107 (31%), Positives = 53/107 (49%), Gaps = 2/107 (1%)
Frame = +2
Query: 230 NIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAA-ATTA 403
++ E + L+ W D +L WN ++G T L V SE +W PD+VL N A A
Sbjct: 97 DVDEKNQMMTTNVWLKQEWSDYKLRWNPADFGNITSLRVPSEMIWIPDIVLYNNADGEFA 156
Query: 404 GDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 544
+ +A + + G+V W+ + S+ + +P D Q C KFGS
Sbjct: 157 VTHMTKAHLFSTGTVHWVPPAIYKSSCSIDVTFFPFDQQNCKMKFGS 203
>Y08419-1|CAA69696.1| 468|Homo sapiens nicotinic acetylcholine
receptor alpha5 subunit precursor protein.
Length = 468
Score = 62.1 bits (144), Expect = 3e-09
Identities = 36/141 (25%), Positives = 66/141 (46%), Gaps = 6/141 (4%)
Frame = +2
Query: 140 MIDSLLATYDRDSPP----DSKIVVNLTLHLRH-ANIRESESTVRIQADLQMNWIDKRLS 304
++ L Y+R P + KI + L + ++ E + L+ WID +L
Sbjct: 50 LLKDLFQDYERWVRPVEHLNDKIKIKFGLAISQLVDVDEKNQLMTTNVWLKQEWIDVKLR 109
Query: 305 WNAGEWG-CSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVSWIKRLDISTP 481
WN ++G V S+ +W PD+VL + A + + + NG+V+W + +
Sbjct: 110 WNPDDYGGIKVIRVPSDSVWTPDIVLFDNADGRFEGTSTKTVIRYNGTVTWTPPANYKSS 169
Query: 482 ISMQLDNWPNDMQTCTFKFGS 544
++ + +P D+Q C+ KFGS
Sbjct: 170 CTIDVTFFPFDLQNCSMKFGS 190
>Y08418-1|CAA69695.1| 503|Homo sapiens nicotinic acetylcholine
receptor alpha3 subunit precursor protein.
Length = 503
Score = 62.1 bits (144), Expect = 3e-09
Identities = 30/93 (32%), Positives = 50/93 (53%), Gaps = 2/93 (2%)
Frame = +2
Query: 272 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 445
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 85 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 144
Query: 446 VSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 544
V+WI + + + +P D Q CT KFGS
Sbjct: 145 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGS 177
>X53559-1|CAA37625.1| 474|Homo sapiens neuronal nicotinic
acetylcholine receptor alpha-3merase protein.
Length = 474
Score = 62.1 bits (144), Expect = 3e-09
Identities = 30/93 (32%), Positives = 50/93 (53%), Gaps = 2/93 (2%)
Frame = +2
Query: 272 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 445
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 56 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 115
Query: 446 VSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 544
V+WI + + + +P D Q CT KFGS
Sbjct: 116 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGS 148
>U62434-1|AAB40112.1| 468|Homo sapiens nicotinic acetylcholine
receptor alpha5 subunit precursor protein.
Length = 468
Score = 62.1 bits (144), Expect = 3e-09
Identities = 36/141 (25%), Positives = 66/141 (46%), Gaps = 6/141 (4%)
Frame = +2
Query: 140 MIDSLLATYDRDSPP----DSKIVVNLTLHLRH-ANIRESESTVRIQADLQMNWIDKRLS 304
++ L Y+R P + KI + L + ++ E + L+ WID +L
Sbjct: 50 LLKDLFQDYERWVRPVEHLNDKIKIKFGLAISQLVDVDEKNQLMTTNVWLKQEWIDVKLR 109
Query: 305 WNAGEWG-CSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVSWIKRLDISTP 481
WN ++G V S+ +W PD+VL + A + + + NG+V+W + +
Sbjct: 110 WNPDDYGGIKVIRVPSDSVWTPDIVLFDNADGRFEGTSTKTVIRYNGTVTWTPPANYKSS 169
Query: 482 ISMQLDNWPNDMQTCTFKFGS 544
++ + +P D+Q C+ KFGS
Sbjct: 170 CTIDVTFFPFDLQNCSMKFGS 190
>U62432-1|AAB40110.1| 504|Homo sapiens nicotinic acetylcholine
receptor alpha3 subunit precursor protein.
Length = 504
Score = 62.1 bits (144), Expect = 3e-09
Identities = 30/93 (32%), Positives = 50/93 (53%), Gaps = 2/93 (2%)
Frame = +2
Query: 272 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 445
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 86 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 145
Query: 446 VSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 544
V+WI + + + +P D Q CT KFGS
Sbjct: 146 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGS 178
>M37981-1|AAA59942.1| 503|Homo sapiens neuronal nicotinic
acetylcholine receptor protein.
Length = 503
Score = 62.1 bits (144), Expect = 3e-09
Identities = 30/93 (32%), Positives = 50/93 (53%), Gaps = 2/93 (2%)
Frame = +2
Query: 272 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 445
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 85 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 144
Query: 446 VSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 544
V+WI + + + +P D Q CT KFGS
Sbjct: 145 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGS 177
>BT006897-1|AAP35543.1| 505|Homo sapiens cholinergic receptor,
nicotinic, alpha polypeptide 3 protein.
Length = 505
Score = 62.1 bits (144), Expect = 3e-09
Identities = 30/93 (32%), Positives = 50/93 (53%), Gaps = 2/93 (2%)
Frame = +2
Query: 272 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 445
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 87 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 146
Query: 446 VSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 544
V+WI + + + +P D Q CT KFGS
Sbjct: 147 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGS 179
>BT006646-1|AAP35292.1| 489|Homo sapiens cholinergic receptor,
nicotinic, alpha polypeptide 3 protein.
Length = 489
Score = 62.1 bits (144), Expect = 3e-09
Identities = 30/93 (32%), Positives = 50/93 (53%), Gaps = 2/93 (2%)
Frame = +2
Query: 272 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 445
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 87 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 146
Query: 446 VSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 544
V+WI + + + +P D Q CT KFGS
Sbjct: 147 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGS 179
>BC098443-1|AAH98443.1| 504|Homo sapiens cholinergic receptor,
nicotinic, alpha 3 protein.
Length = 504
Score = 62.1 bits (144), Expect = 3e-09
Identities = 30/93 (32%), Positives = 50/93 (53%), Gaps = 2/93 (2%)
Frame = +2
Query: 272 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 445
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 86 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 145
Query: 446 VSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 544
V+WI + + + +P D Q CT KFGS
Sbjct: 146 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGS 178
>BC033639-1|AAH33639.1| 468|Homo sapiens cholinergic receptor,
nicotinic, alpha 5 protein.
Length = 468
Score = 62.1 bits (144), Expect = 3e-09
Identities = 36/141 (25%), Positives = 66/141 (46%), Gaps = 6/141 (4%)
Frame = +2
Query: 140 MIDSLLATYDRDSPP----DSKIVVNLTLHLRH-ANIRESESTVRIQADLQMNWIDKRLS 304
++ L Y+R P + KI + L + ++ E + L+ WID +L
Sbjct: 50 LLKDLFQDYERWVRPVEHLNDKIKIKFGLAISQLVDVDEKNQLMTTNVWLKQEWIDVKLR 109
Query: 305 WNAGEWG-CSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVSWIKRLDISTP 481
WN ++G V S+ +W PD+VL + A + + + NG+V+W + +
Sbjct: 110 WNPDDYGGIKVIRVPSDSVWTPDIVLFDNADGRFEGTSTKTVIRYNGTVTWTPPANYKSS 169
Query: 482 ISMQLDNWPNDMQTCTFKFGS 544
++ + +P D+Q C+ KFGS
Sbjct: 170 CTIDVTFFPFDLQNCSMKFGS 190
>BC006114-1|AAH06114.1| 489|Homo sapiens CHRNA3 protein protein.
Length = 489
Score = 62.1 bits (144), Expect = 3e-09
Identities = 30/93 (32%), Positives = 50/93 (53%), Gaps = 2/93 (2%)
Frame = +2
Query: 272 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 445
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 87 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 146
Query: 446 VSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 544
V+WI + + + +P D Q CT KFGS
Sbjct: 147 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGS 179
>BC002996-1|AAH02996.1| 505|Homo sapiens cholinergic receptor,
nicotinic, alpha 3 protein.
Length = 505
Score = 62.1 bits (144), Expect = 3e-09
Identities = 30/93 (32%), Positives = 50/93 (53%), Gaps = 2/93 (2%)
Frame = +2
Query: 272 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 445
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 87 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 146
Query: 446 VSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 544
V+WI + + + +P D Q CT KFGS
Sbjct: 147 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGS 179
>BC001642-1|AAH01642.1| 505|Homo sapiens cholinergic receptor,
nicotinic, alpha 3 protein.
Length = 505
Score = 62.1 bits (144), Expect = 3e-09
Identities = 30/93 (32%), Positives = 50/93 (53%), Gaps = 2/93 (2%)
Frame = +2
Query: 272 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 445
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 87 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 146
Query: 446 VSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 544
V+WI + + + +P D Q CT KFGS
Sbjct: 147 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGS 179
>BC000513-1|AAH00513.1| 505|Homo sapiens cholinergic receptor,
nicotinic, alpha 3 protein.
Length = 505
Score = 62.1 bits (144), Expect = 3e-09
Identities = 30/93 (32%), Positives = 50/93 (53%), Gaps = 2/93 (2%)
Frame = +2
Query: 272 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 445
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 87 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 146
Query: 446 VSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 544
V+WI + + + +P D Q CT KFGS
Sbjct: 147 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGS 179
>AJ306481-1|CAC34820.1| 468|Homo sapiens neuronal nicotinic
acetylcholine receptor alpha-5subunit protein.
Length = 468
Score = 62.1 bits (144), Expect = 3e-09
Identities = 36/141 (25%), Positives = 66/141 (46%), Gaps = 6/141 (4%)
Frame = +2
Query: 140 MIDSLLATYDRDSPP----DSKIVVNLTLHLRH-ANIRESESTVRIQADLQMNWIDKRLS 304
++ L Y+R P + KI + L + ++ E + L+ WID +L
Sbjct: 50 LLKDLFQDYERWVRPVEHLNDKIKIKFGLAISQLVDVDEKNQLMTTNVWLKQEWIDVKLR 109
Query: 305 WNAGEWG-CSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVSWIKRLDISTP 481
WN ++G V S+ +W PD+VL + A + + + NG+V+W + +
Sbjct: 110 WNPDDYGGIKVIRVPSDSVWTPDIVLFDNADGRFEGTSTKTVIRYNGTVTWTPPANYKSS 169
Query: 482 ISMQLDNWPNDMQTCTFKFGS 544
++ + +P D+Q C+ KFGS
Sbjct: 170 CTIDVTFFPFDLQNCSMKFGS 190
>AJ007783-1|CAA07682.1| 504|Homo sapiens nicotinic acetylcholine
receptor alpha-3 subunit protein.
Length = 504
Score = 62.1 bits (144), Expect = 3e-09
Identities = 30/93 (32%), Positives = 50/93 (53%), Gaps = 2/93 (2%)
Frame = +2
Query: 272 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 445
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 86 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 145
Query: 446 VSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 544
V+WI + + + +P D Q CT KFGS
Sbjct: 146 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGS 178
>AF385584-1|AAK68110.1| 489|Homo sapiens nicotinic cholinergic
receptor alpha 3 protein.
Length = 489
Score = 62.1 bits (144), Expect = 3e-09
Identities = 30/93 (32%), Positives = 50/93 (53%), Gaps = 2/93 (2%)
Frame = +2
Query: 272 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 445
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 81 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 140
Query: 446 VSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 544
V+WI + + + +P D Q CT KFGS
Sbjct: 141 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGS 173
>Y16282-1|CAA76155.1| 494|Homo sapiens nicotinic acetylcholine
receptor alpha6 subunit precursor protein.
Length = 494
Score = 61.3 bits (142), Expect = 4e-09
Identities = 40/154 (25%), Positives = 71/154 (46%), Gaps = 10/154 (6%)
Frame = +2
Query: 113 CENATSLSLMIDSLLATYDRDSPPDSKIVVNLTLHL-----RHANIRESESTVRIQADLQ 277
C + + L + Y++ P + +T+H + AN+ E + L+
Sbjct: 28 CVGCATEERLFHKLFSHYNQFIRPVENVSDPVTVHFEVAITQLANVDEVNQIMETNLWLR 87
Query: 278 MNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNG 442
W D +L W+ E+ G T V ++++W+PD+VL N A GD+ + +A + NG
Sbjct: 88 HIWNDYKLRWDPMEYDGIETLRVPADKIWKPDIVLYNNAV---GDFQVEGKTKALLKYNG 144
Query: 443 SVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 544
++W + M + +P D Q C+ KFGS
Sbjct: 145 MITWTPPAIFKSSCPMDITFFPFDHQNCSLKFGS 178
>U62435-1|AAB40113.1| 494|Homo sapiens nicotinic acetylcholine
receptor alpha6 subunit precursor protein.
Length = 494
Score = 61.3 bits (142), Expect = 4e-09
Identities = 40/154 (25%), Positives = 71/154 (46%), Gaps = 10/154 (6%)
Frame = +2
Query: 113 CENATSLSLMIDSLLATYDRDSPPDSKIVVNLTLHL-----RHANIRESESTVRIQADLQ 277
C + + L + Y++ P + +T+H + AN+ E + L+
Sbjct: 28 CVGCATEERLFHKLFSHYNQFIRPVENVSDPVTVHFEVAITQLANVDEVNQIMETNLWLR 87
Query: 278 MNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNG 442
W D +L W+ E+ G T V ++++W+PD+VL N A GD+ + +A + NG
Sbjct: 88 HIWNDYKLRWDPMEYDGIETLRVPADKIWKPDIVLYNNAV---GDFQVEGKTKALLKYNG 144
Query: 443 SVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 544
++W + M + +P D Q C+ KFGS
Sbjct: 145 MITWTPPAIFKSSCPMDITFFPFDHQNCSLKFGS 178
>BC014456-1|AAH14456.1| 494|Homo sapiens cholinergic receptor,
nicotinic, alpha 6 protein.
Length = 494
Score = 61.3 bits (142), Expect = 4e-09
Identities = 40/154 (25%), Positives = 71/154 (46%), Gaps = 10/154 (6%)
Frame = +2
Query: 113 CENATSLSLMIDSLLATYDRDSPPDSKIVVNLTLHL-----RHANIRESESTVRIQADLQ 277
C + + L + Y++ P + +T+H + AN+ E + L+
Sbjct: 28 CVGCATEERLFHKLFSHYNQFIRPVENVSDPVTVHFEVAITQLANVDEVNQIMETNLWLR 87
Query: 278 MNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNG 442
W D +L W+ E+ G T V ++++W+PD+VL N A GD+ + +A + NG
Sbjct: 88 HIWNDYKLRWDPMEYDGIETLRVPADKIWKPDIVLYNNAV---GDFQVEGKTKALLKYNG 144
Query: 443 SVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 544
++W + M + +P D Q C+ KFGS
Sbjct: 145 MITWTPPAIFKSSCPMDITFFPFDHQNCSLKFGS 178
>AB079251-1|BAC06855.1| 494|Homo sapiens Nicotinic acetylcholine
receptor alpha 6 protein.
Length = 494
Score = 61.3 bits (142), Expect = 4e-09
Identities = 40/154 (25%), Positives = 71/154 (46%), Gaps = 10/154 (6%)
Frame = +2
Query: 113 CENATSLSLMIDSLLATYDRDSPPDSKIVVNLTLHL-----RHANIRESESTVRIQADLQ 277
C + + L + Y++ P + +T+H + AN+ E + L+
Sbjct: 28 CVGCATEERLFHKLFSHYNQFIRPVENVSDPVTVHFEVAITQLANVDEVNQIMETNLWLR 87
Query: 278 MNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNG 442
W D +L W+ E+ G T V ++++W+PD+VL N A GD+ + +A + NG
Sbjct: 88 HIWNDYKLRWDPMEYDGIETLRVPADKIWKPDIVLYNNAV---GDFQVEGKTKALLKYNG 144
Query: 443 SVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 544
++W + M + +P D Q C+ KFGS
Sbjct: 145 MITWTPPAIFKSSCPMDITFFPFDHQNCSLKFGS 178
>M83712-1|AAA58357.1| 468|Homo sapiens nicotinic receptor alpha 5
subunit protein.
Length = 468
Score = 60.9 bits (141), Expect = 6e-09
Identities = 36/141 (25%), Positives = 65/141 (46%), Gaps = 6/141 (4%)
Frame = +2
Query: 140 MIDSLLATYDRDSPP----DSKIVVNLTLHLRH-ANIRESESTVRIQADLQMNWIDKRLS 304
++ L Y+R P + KI + L + ++ E + L+ WID +L
Sbjct: 50 LLKDLFQDYERWVRPVEHLNDKIKIKFGLAISQLVDVDEKNQLMTTNVWLKQEWIDVKLR 109
Query: 305 WNAGEWG-CSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVSWIKRLDISTP 481
WN ++G V S+ W PD+VL + A + + + NG+V+W + +
Sbjct: 110 WNPDDYGGIKVIRVPSDSSWTPDIVLFDNADGRFEGTSTKTVIRYNGTVTWTPPANYKSS 169
Query: 482 ISMQLDNWPNDMQTCTFKFGS 544
++ + +P D+Q C+ KFGS
Sbjct: 170 CTIDVTFFPFDLQNCSMKFGS 190
>X14830-1|CAA32939.1| 501|Homo sapiens protein ( Human mRNA for
muscle acetylcholine receptor beta-subunit. ).
Length = 501
Score = 60.5 bits (140), Expect = 8e-09
Identities = 43/122 (35%), Positives = 63/122 (51%), Gaps = 4/122 (3%)
Frame = +2
Query: 191 KIVVNLTL-HLRHANIRESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWR 364
++ V L L L N ++ E + ++ DL+ W D RLSW+ E G + +++E +W
Sbjct: 53 RVSVGLILAQLISLNEKDEEMSTKVYLDLE--WTDYRLSWDPAEHDGIDSLRITAESVWL 110
Query: 365 PDVVLLNAAATTAGDYAL--RARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKF 538
PDVVLLN D AL VS++GSV W + S+Q+ +P D Q CT F
Sbjct: 111 PDVVLLNNNDGNF-DVALDISVVVSSDGSVRWQPPGIYRSSCSIQVTYFPFDWQNCTMVF 169
Query: 539 GS 544
S
Sbjct: 170 SS 171
>BC011371-1|AAH11371.1| 501|Homo sapiens cholinergic receptor,
nicotinic, beta 1 (muscle) protein.
Length = 501
Score = 60.5 bits (140), Expect = 8e-09
Identities = 43/122 (35%), Positives = 63/122 (51%), Gaps = 4/122 (3%)
Frame = +2
Query: 191 KIVVNLTL-HLRHANIRESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWR 364
++ V L L L N ++ E + ++ DL+ W D RLSW+ E G + +++E +W
Sbjct: 53 RVSVGLILAQLISLNEKDEEMSTKVYLDLE--WTDYRLSWDPAEHDGIDSLRITAESVWL 110
Query: 365 PDVVLLNAAATTAGDYAL--RARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKF 538
PDVVLLN D AL VS++GSV W + S+Q+ +P D Q CT F
Sbjct: 111 PDVVLLNNNDGNF-DVALDISVVVSSDGSVRWQPPGIYRSSCSIQVTYFPFDWQNCTMVF 169
Query: 539 GS 544
S
Sbjct: 170 SS 171
>M86383-1|AAC84176.1| 502|Homo sapiens nicotinic acetylcholine
receptor alpha 3 subunit precursor protein.
Length = 502
Score = 59.7 bits (138), Expect = 1e-08
Identities = 31/96 (32%), Positives = 52/96 (54%), Gaps = 5/96 (5%)
Frame = +2
Query: 272 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYAL----RARVSN 436
L+ W D +L WN +G + ++ V ++++W+PD+VL N A GD+ + +A +
Sbjct: 84 LKQIWNDYKLKWNPSGYGGAEFMRVPAQKIWKPDIVLYNNAV---GDFQVTTKTKALLKY 140
Query: 437 NGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 544
G V+WI + + + +P D Q CT KFGS
Sbjct: 141 TGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGS 176
>Y08421-1|CAA69698.1| 627|Homo sapiens nicotinic acetylcholine
receptor alpha4 subunit precursor protein.
Length = 627
Score = 59.3 bits (137), Expect = 2e-08
Identities = 42/145 (28%), Positives = 72/145 (49%), Gaps = 10/145 (6%)
Frame = +2
Query: 140 MIDSLLATYDRDSPPDSKI--VVNLTLHLRHA---NIRESESTVRIQADLQMNWIDKRLS 304
++ L + Y++ S P + I VV + L A ++ E + ++ W D +L
Sbjct: 40 LLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLR 99
Query: 305 WNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNGSVSWIKRLD 469
W+ ++ T + + SE +WRPD+VL N A GD+A+ +A + ++G V W
Sbjct: 100 WDPADYENVTSIRIPSELIWRPDIVLYNNAD---GDFAVTHLTKAHLFHDGRVQWTPPAI 156
Query: 470 ISTPISMQLDNWPNDMQTCTFKFGS 544
+ S+ + +P D Q CT KFGS
Sbjct: 157 YKSSCSIDVTFFPFDQQNCTMKFGS 181
>X89741-1|CAA61893.1| 627|Homo sapiens neuronal acetylcholine
receptor alpha-4 subunit protein.
Length = 627
Score = 59.3 bits (137), Expect = 2e-08
Identities = 42/145 (28%), Positives = 72/145 (49%), Gaps = 10/145 (6%)
Frame = +2
Query: 140 MIDSLLATYDRDSPPDSKI--VVNLTLHLRHA---NIRESESTVRIQADLQMNWIDKRLS 304
++ L + Y++ S P + I VV + L A ++ E + ++ W D +L
Sbjct: 40 LLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLR 99
Query: 305 WNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNGSVSWIKRLD 469
W+ ++ T + + SE +WRPD+VL N A GD+A+ +A + ++G V W
Sbjct: 100 WDPADYENVTSIRIPSELIWRPDIVLYNNAD---GDFAVTHLTKAHLFHDGRVQWTPPAI 156
Query: 470 ISTPISMQLDNWPNDMQTCTFKFGS 544
+ S+ + +P D Q CT KFGS
Sbjct: 157 YKSSCSIDVTFFPFDQQNCTMKFGS 181
>X87629-1|CAA60959.1| 602|Homo sapiens nicotinic acetylcholine
receptor protein.
Length = 602
Score = 59.3 bits (137), Expect = 2e-08
Identities = 42/145 (28%), Positives = 72/145 (49%), Gaps = 10/145 (6%)
Frame = +2
Query: 140 MIDSLLATYDRDSPPDSKI--VVNLTLHLRHA---NIRESESTVRIQADLQMNWIDKRLS 304
++ L + Y++ S P + I VV + L A ++ E + ++ W D +L
Sbjct: 15 LLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLR 74
Query: 305 WNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNGSVSWIKRLD 469
W+ ++ T + + SE +WRPD+VL N A GD+A+ +A + ++G V W
Sbjct: 75 WDPADYENVTSIRIPSELIWRPDIVLYNNAD---GDFAVTHLTKAHLFHDGRVQWTPPAI 131
Query: 470 ISTPISMQLDNWPNDMQTCTFKFGS 544
+ S+ + +P D Q CT KFGS
Sbjct: 132 YKSSCSIDVTFFPFDQQNCTMKFGS 156
>U62433-1|AAB40111.1| 627|Homo sapiens nicotinic acetylcholine
receptor alpha4 subunit precursor protein.
Length = 627
Score = 59.3 bits (137), Expect = 2e-08
Identities = 42/145 (28%), Positives = 72/145 (49%), Gaps = 10/145 (6%)
Frame = +2
Query: 140 MIDSLLATYDRDSPPDSKI--VVNLTLHLRHA---NIRESESTVRIQADLQMNWIDKRLS 304
++ L + Y++ S P + I VV + L A ++ E + ++ W D +L
Sbjct: 40 LLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLR 99
Query: 305 WNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNGSVSWIKRLD 469
W+ ++ T + + SE +WRPD+VL N A GD+A+ +A + ++G V W
Sbjct: 100 WDPADYENVTSIRIPSELIWRPDIVLYNNAD---GDFAVTHLTKAHLFHDGRVQWTPPAI 156
Query: 470 ISTPISMQLDNWPNDMQTCTFKFGS 544
+ S+ + +P D Q CT KFGS
Sbjct: 157 YKSSCSIDVTFFPFDQQNCTMKFGS 181
>L35901-1|AAA64743.1| 627|Homo sapiens nicotinic acetylcholine
receptor alpha 4 subunit protein.
Length = 627
Score = 59.3 bits (137), Expect = 2e-08
Identities = 42/145 (28%), Positives = 72/145 (49%), Gaps = 10/145 (6%)
Frame = +2
Query: 140 MIDSLLATYDRDSPPDSKI--VVNLTLHLRHA---NIRESESTVRIQADLQMNWIDKRLS 304
++ L + Y++ S P + I VV + L A ++ E + ++ W D +L
Sbjct: 40 LLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLR 99
Query: 305 WNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNGSVSWIKRLD 469
W+ ++ T + + SE +WRPD+VL N A GD+A+ +A + ++G V W
Sbjct: 100 WDPADYENVTSIRIPSELIWRPDIVLYNNAD---GDFAVTHLTKAHLFHDGRVQWTPPAI 156
Query: 470 ISTPISMQLDNWPNDMQTCTFKFGS 544
+ S+ + +P D Q CT KFGS
Sbjct: 157 YKSSCSIDVTFFPFDQQNCTMKFGS 181
>DQ093071-1|AAY88737.1| 627|Homo sapiens cholinergic receptor,
nicotinic, alpha polypeptide 4 protein.
Length = 627
Score = 59.3 bits (137), Expect = 2e-08
Identities = 42/145 (28%), Positives = 72/145 (49%), Gaps = 10/145 (6%)
Frame = +2
Query: 140 MIDSLLATYDRDSPPDSKI--VVNLTLHLRHA---NIRESESTVRIQADLQMNWIDKRLS 304
++ L + Y++ S P + I VV + L A ++ E + ++ W D +L
Sbjct: 40 LLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLR 99
Query: 305 WNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNGSVSWIKRLD 469
W+ ++ T + + SE +WRPD+VL N A GD+A+ +A + ++G V W
Sbjct: 100 WDPADYENVTSIRIPSELIWRPDIVLYNNAD---GDFAVTHLTKAHLFHDGRVQWTPPAI 156
Query: 470 ISTPISMQLDNWPNDMQTCTFKFGS 544
+ S+ + +P D Q CT KFGS
Sbjct: 157 YKSSCSIDVTFFPFDQQNCTMKFGS 181
>BC096290-1|AAH96290.1| 627|Homo sapiens cholinergic receptor,
nicotinic, alpha 4 protein.
Length = 627
Score = 59.3 bits (137), Expect = 2e-08
Identities = 42/145 (28%), Positives = 72/145 (49%), Gaps = 10/145 (6%)
Frame = +2
Query: 140 MIDSLLATYDRDSPPDSKI--VVNLTLHLRHA---NIRESESTVRIQADLQMNWIDKRLS 304
++ L + Y++ S P + I VV + L A ++ E + ++ W D +L
Sbjct: 40 LLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLR 99
Query: 305 WNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNGSVSWIKRLD 469
W+ ++ T + + SE +WRPD+VL N A GD+A+ +A + ++G V W
Sbjct: 100 WDPADYENVTSIRIPSELIWRPDIVLYNNAD---GDFAVTHLTKAHLFHDGRVQWTPPAI 156
Query: 470 ISTPISMQLDNWPNDMQTCTFKFGS 544
+ S+ + +P D Q CT KFGS
Sbjct: 157 YKSSCSIDVTFFPFDQQNCTMKFGS 181
>BC023553-1|AAH23553.1| 501|Homo sapiens cholinergic receptor,
nicotinic, beta 1 (muscle) protein.
Length = 501
Score = 59.3 bits (137), Expect = 2e-08
Identities = 41/124 (33%), Positives = 64/124 (51%), Gaps = 6/124 (4%)
Frame = +2
Query: 191 KIVVNLTL-HLRHANIRESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWR 364
++ V L L L N ++ E + ++ DL+ W D RLSW+ E G + +++E +W
Sbjct: 53 RVSVGLILAQLISLNEKDEEMSTKVYLDLE--WTDYRLSWDPAEHDGIDSLRITAESVWL 110
Query: 365 PDVVLLNAAATTAGDY----ALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTF 532
PDVVLLN G++ + VS++GSV W + S+Q+ +P D Q CT
Sbjct: 111 PDVVLLN---NNDGNFYVALDISVVVSSDGSVRWQPPGIYRSSCSIQVTYFPFDWQNCTM 167
Query: 533 KFGS 544
F S
Sbjct: 168 VFSS 171
>Y00762-1|CAA68731.1| 457|Homo sapiens protein ( Human mRNA for
muscle acetylcholine receptor alpha-subunit. ).
Length = 457
Score = 58.8 bits (136), Expect = 2e-08
Identities = 34/123 (27%), Positives = 61/123 (49%), Gaps = 5/123 (4%)
Frame = +2
Query: 191 KIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRP 367
++ V L L ++ N+ E V L+ W+D L WN ++G + + SE++WRP
Sbjct: 50 EVTVGLQL-IQLINVDEVNQIVTTNVRLKQQWVDYNLKWNPDDYGGVKKIHIPSEKIWRP 108
Query: 368 DVVLLNAAATTAGDYAL----RARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFK 535
D+VL N A GD+A+ + + G ++W + + + ++P D Q C+ K
Sbjct: 109 DLVLYNNA---DGDFAIVKFTKVLLQYTGHITWTPPAIFKSYCEIIVTHFPFDEQNCSMK 165
Query: 536 FGS 544
G+
Sbjct: 166 LGT 168
>X02502-1|CAA26344.1| 457|Homo sapiens acetylcholine receptor
protein.
Length = 457
Score = 58.8 bits (136), Expect = 2e-08
Identities = 34/123 (27%), Positives = 61/123 (49%), Gaps = 5/123 (4%)
Frame = +2
Query: 191 KIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRP 367
++ V L L ++ N+ E V L+ W+D L WN ++G + + SE++WRP
Sbjct: 50 EVTVGLQL-IQLINVDEVNQIVTTNVRLKQQWVDYNLKWNPDDYGGVKKIHIPSEKIWRP 108
Query: 368 DVVLLNAAATTAGDYAL----RARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFK 535
D+VL N A GD+A+ + + G ++W + + + ++P D Q C+ K
Sbjct: 109 DLVLYNNA---DGDFAIVKFTKVLLQYTGHITWTPPAIFKSYCEIIVTHFPFDEQNCSMK 165
Query: 536 FGS 544
G+
Sbjct: 166 LGT 168
>S77094-1|AAD14247.1| 457|Homo sapiens nicotinic acetylcholine
receptor alpha subunit|AChR protein.
Length = 457
Score = 58.8 bits (136), Expect = 2e-08
Identities = 34/123 (27%), Positives = 61/123 (49%), Gaps = 5/123 (4%)
Frame = +2
Query: 191 KIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRP 367
++ V L L ++ N+ E V L+ W+D L WN ++G + + SE++WRP
Sbjct: 50 EVTVGLQL-IQLINVDEVNQIVTTNVRLKQQWVDYNLKWNPDDYGGVKKIHIPSEKIWRP 108
Query: 368 DVVLLNAAATTAGDYAL----RARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFK 535
D+VL N A GD+A+ + + G ++W + + + ++P D Q C+ K
Sbjct: 109 DLVLYNNA---DGDFAIVKFTKVLLQYTGHITWTPPAIFKSYCEIIVTHFPFDEQNCSMK 165
Query: 536 FGS 544
G+
Sbjct: 166 LGT 168
>BC006314-1|AAH06314.1| 269|Homo sapiens CHRNA1 protein protein.
Length = 269
Score = 58.8 bits (136), Expect = 2e-08
Identities = 34/123 (27%), Positives = 61/123 (49%), Gaps = 5/123 (4%)
Frame = +2
Query: 191 KIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRP 367
++ V L L ++ N+ E V L+ W+D L WN ++G + + SE++WRP
Sbjct: 50 EVTVGLQL-IQLINVDEVNQIVTTNVRLKQQWVDYNLKWNPDDYGGVKKIHIPSEKIWRP 108
Query: 368 DVVLLNAAATTAGDYAL----RARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFK 535
D+VL N A GD+A+ + + G ++W + + + ++P D Q C+ K
Sbjct: 109 DLVLYNNA---DGDFAIVKFTKVLLQYTGHITWTPPAIFKSYCEIIVTHFPFDEQNCSMK 165
Query: 536 FGS 544
G+
Sbjct: 166 LGT 168
>AC018890-1|AAY14687.1| 457|Homo sapiens unknown protein.
Length = 457
Score = 58.8 bits (136), Expect = 2e-08
Identities = 34/123 (27%), Positives = 61/123 (49%), Gaps = 5/123 (4%)
Frame = +2
Query: 191 KIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRP 367
++ V L L ++ N+ E V L+ W+D L WN ++G + + SE++WRP
Sbjct: 50 EVTVGLQL-IQLINVDEVNQIVTTNVRLKQQWVDYNLKWNPDDYGGVKKIHIPSEKIWRP 108
Query: 368 DVVLLNAAATTAGDYAL----RARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFK 535
D+VL N A GD+A+ + + G ++W + + + ++P D Q C+ K
Sbjct: 109 DLVLYNNA---DGDFAIVKFTKVLLQYTGHITWTPPAIFKSYCEIIVTHFPFDEQNCSMK 165
Query: 536 FGS 544
G+
Sbjct: 166 LGT 168
>Y08415-1|CAA69692.1| 502|Homo sapiens nicotinic acetylcholine
receptor beta2 subunit precursor protein.
Length = 502
Score = 55.6 bits (128), Expect = 2e-07
Identities = 35/120 (29%), Positives = 55/120 (45%), Gaps = 3/120 (2%)
Frame = +2
Query: 194 IVVNLTLHLRHA-NIRESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 367
+ V L + L ++ E E + L W D RL+W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 368 DVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 544
DVVL N A + A VS +GS+ W+ + +++ ++P D Q CT KF S
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRS 175
>X53179-1|CAA37320.1| 502|Homo sapiens precursor peptide (AA -25 to
477) protein.
Length = 502
Score = 55.6 bits (128), Expect = 2e-07
Identities = 35/120 (29%), Positives = 55/120 (45%), Gaps = 3/120 (2%)
Frame = +2
Query: 194 IVVNLTLHLRHA-NIRESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 367
+ V L + L ++ E E + L W D RL+W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 368 DVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 544
DVVL N A + A VS +GS+ W+ + +++ ++P D Q CT KF S
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRS 175
>X01715-1|CAA25861.1| 520|Homo sapiens acetylcholine receptor gamma
chain precursor protein.
Length = 520
Score = 55.6 bits (128), Expect = 2e-07
Identities = 41/144 (28%), Positives = 67/144 (46%), Gaps = 8/144 (5%)
Frame = +2
Query: 140 MIDSLLATYDRDSPPDSKI--VVNLTLHLRHANI---RESESTVRIQADLQMNWIDKRLS 304
++ L+ YD + P + VVN++L L N+ E E + ++M W D RL
Sbjct: 32 LLADLMQNYDPNLRPAERDSDVVNVSLKLTLTNLISLNEREEALTTNVWIEMQWCDYRLR 91
Query: 305 WNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYAL--RARVSNNGSVSWIKRLDIS 475
W+ ++ G V S +WRPD+VL N + AL VS +G + W+
Sbjct: 92 WDPRDYEGLWVLRVPSTMVWRPDIVLEN-NVDGVFEVALYCNVLVSPDGCIYWLPPAIFR 150
Query: 476 TPISMQLDNWPNDMQTCTFKFGSR 547
+ S+ + +P D Q C+ F S+
Sbjct: 151 SACSISVTYFPFDWQNCSLIFQSQ 174
>U62437-1|AAB40115.1| 502|Homo sapiens nicotinic acetylcholine
receptor beta2 subunit precursor protein.
Length = 502
Score = 55.6 bits (128), Expect = 2e-07
Identities = 35/120 (29%), Positives = 55/120 (45%), Gaps = 3/120 (2%)
Frame = +2
Query: 194 IVVNLTLHLRHA-NIRESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 367
+ V L + L ++ E E + L W D RL+W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 368 DVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 544
DVVL N A + A VS +GS+ W+ + +++ ++P D Q CT KF S
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRS 175
>BC075041-1|AAH75041.1| 502|Homo sapiens cholinergic receptor,
nicotinic, beta 2 (neuronal) protein.
Length = 502
Score = 55.6 bits (128), Expect = 2e-07
Identities = 35/120 (29%), Positives = 55/120 (45%), Gaps = 3/120 (2%)
Frame = +2
Query: 194 IVVNLTLHLRHA-NIRESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 367
+ V L + L ++ E E + L W D RL+W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 368 DVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 544
DVVL N A + A VS +GS+ W+ + +++ ++P D Q CT KF S
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRS 175
>BC075040-1|AAH75040.1| 502|Homo sapiens cholinergic receptor,
nicotinic, beta 2 (neuronal) protein.
Length = 502
Score = 55.6 bits (128), Expect = 2e-07
Identities = 35/120 (29%), Positives = 55/120 (45%), Gaps = 3/120 (2%)
Frame = +2
Query: 194 IVVNLTLHLRHA-NIRESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 367
+ V L + L ++ E E + L W D RL+W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 368 DVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 544
DVVL N A + A VS +GS+ W+ + +++ ++P D Q CT KF S
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRS 175
>AL592078-3|CAI16184.1| 502|Homo sapiens cholinergic receptor,
nicotinic, beta 2 (neuronal) protein.
Length = 502
Score = 55.6 bits (128), Expect = 2e-07
Identities = 35/120 (29%), Positives = 55/120 (45%), Gaps = 3/120 (2%)
Frame = +2
Query: 194 IVVNLTLHLRHA-NIRESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 367
+ V L + L ++ E E + L W D RL+W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 368 DVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 544
DVVL N A + A VS +GS+ W+ + +++ ++P D Q CT KF S
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRS 175
>AJ001935-1|CAA05108.1| 504|Homo sapiens CHRNB2 protein.
Length = 504
Score = 55.6 bits (128), Expect = 2e-07
Identities = 35/120 (29%), Positives = 55/120 (45%), Gaps = 3/120 (2%)
Frame = +2
Query: 194 IVVNLTLHLRHA-NIRESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 367
+ V L + L ++ E E + L W D RL+W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 368 DVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 544
DVVL N A + A VS +GS+ W+ + +++ ++P D Q CT KF S
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRS 175
>AF077186-1|AAD45422.1| 502|Homo sapiens neuronal nicotinic
acetylcholine receptor beta 2 protein.
Length = 502
Score = 55.6 bits (128), Expect = 2e-07
Identities = 35/120 (29%), Positives = 55/120 (45%), Gaps = 3/120 (2%)
Frame = +2
Query: 194 IVVNLTLHLRHA-NIRESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 367
+ V L + L ++ E E + L W D RL+W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 368 DVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 544
DVVL N A + A VS +GS+ W+ + +++ ++P D Q CT KF S
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRS 175
>AC092165-3|AAY24103.1| 520|Homo sapiens unknown protein.
Length = 520
Score = 55.6 bits (128), Expect = 2e-07
Identities = 41/144 (28%), Positives = 67/144 (46%), Gaps = 8/144 (5%)
Frame = +2
Query: 140 MIDSLLATYDRDSPPDSKI--VVNLTLHLRHANI---RESESTVRIQADLQMNWIDKRLS 304
++ L+ YD + P + VVN++L L N+ E E + ++M W D RL
Sbjct: 32 LLADLMQNYDPNLRPAERDSDVVNVSLKLTLTNLISLNEREEALTTNVWIEMQWCDYRLR 91
Query: 305 WNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYAL--RARVSNNGSVSWIKRLDIS 475
W+ ++ G V S +WRPD+VL N + AL VS +G + W+
Sbjct: 92 WDPRDYEGLWVLRVPSTMVWRPDIVLEN-NVDGVFEVALYCNVLVSPDGCIYWLPPAIFR 150
Query: 476 TPISMQLDNWPNDMQTCTFKFGSR 547
+ S+ + +P D Q C+ F S+
Sbjct: 151 SACSISVTYFPFDWQNCSLIFQSQ 174
>X55019-1|CAA38759.1| 517|Homo sapiens acetylcholine receptor delta
subunit protein.
Length = 517
Score = 55.2 bits (127), Expect = 3e-07
Identities = 34/123 (27%), Positives = 58/123 (47%), Gaps = 3/123 (2%)
Frame = +2
Query: 185 DSKIVVNLTLHLRHA-NIRESESTVRIQADLQMNWIDKRLSWNAGEWG-CSTWLVSSERL 358
+ + V L L L + +++E E T+ ++ W D RL WNA E+G S + + +
Sbjct: 49 EESVDVALALTLSNLISLKEVEETLTTNVWIEHGWTDNRLKWNAEEFGNISVLRLPPDMV 108
Query: 359 WRPDVVL-LNAAATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFK 535
W P++VL N + Y+ V + G V W+ + + + +P D Q C+ K
Sbjct: 109 WLPEIVLENNNDGSFQISYSCNVLVYHYGFVYWLPPAIFRSSCPISVTYFPFDWQNCSLK 168
Query: 536 FGS 544
F S
Sbjct: 169 FSS 171
>BC093925-1|AAH93925.1| 517|Homo sapiens cholinergic receptor,
nicotinic, delta protein.
Length = 517
Score = 55.2 bits (127), Expect = 3e-07
Identities = 34/123 (27%), Positives = 58/123 (47%), Gaps = 3/123 (2%)
Frame = +2
Query: 185 DSKIVVNLTLHLRHA-NIRESESTVRIQADLQMNWIDKRLSWNAGEWG-CSTWLVSSERL 358
+ + V L L L + +++E E T+ ++ W D RL WNA E+G S + + +
Sbjct: 49 EESVDVALALTLSNLISLKEVEETLTTNVWIEHGWTDNRLKWNAEEFGNISVLRLPPDMV 108
Query: 359 WRPDVVL-LNAAATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFK 535
W P++VL N + Y+ V + G V W+ + + + +P D Q C+ K
Sbjct: 109 WLPEIVLENNNDGSFQISYSCNVLVYHYGFVYWLPPAIFRSSCPISVTYFPFDWQNCSLK 168
Query: 536 FGS 544
F S
Sbjct: 169 FSS 171
>BC093923-1|AAH93923.1| 517|Homo sapiens cholinergic receptor,
nicotinic, delta protein.
Length = 517
Score = 55.2 bits (127), Expect = 3e-07
Identities = 34/123 (27%), Positives = 58/123 (47%), Gaps = 3/123 (2%)
Frame = +2
Query: 185 DSKIVVNLTLHLRHA-NIRESESTVRIQADLQMNWIDKRLSWNAGEWG-CSTWLVSSERL 358
+ + V L L L + +++E E T+ ++ W D RL WNA E+G S + + +
Sbjct: 49 EESVDVALALTLSNLISLKEVEETLTTNVWIEHGWTDNRLKWNAEEFGNISVLRLPPDMV 108
Query: 359 WRPDVVL-LNAAATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFK 535
W P++VL N + Y+ V + G V W+ + + + +P D Q C+ K
Sbjct: 109 WLPEIVLENNNDGSFQISYSCNVLVYHYGFVYWLPPAIFRSSCPISVTYFPFDWQNCSLK 168
Query: 536 FGS 544
F S
Sbjct: 169 FSS 171
>AC092165-2|AAY24102.1| 517|Homo sapiens unknown protein.
Length = 517
Score = 55.2 bits (127), Expect = 3e-07
Identities = 34/123 (27%), Positives = 58/123 (47%), Gaps = 3/123 (2%)
Frame = +2
Query: 185 DSKIVVNLTLHLRHA-NIRESESTVRIQADLQMNWIDKRLSWNAGEWG-CSTWLVSSERL 358
+ + V L L L + +++E E T+ ++ W D RL WNA E+G S + + +
Sbjct: 49 EESVDVALALTLSNLISLKEVEETLTTNVWIEHGWTDNRLKWNAEEFGNISVLRLPPDMV 108
Query: 359 WRPDVVL-LNAAATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFK 535
W P++VL N + Y+ V + G V W+ + + + +P D Q C+ K
Sbjct: 109 WLPEIVLENNNDGSFQISYSCNVLVYHYGFVYWLPPAIFRSSCPISVTYFPFDWQNCSLK 168
Query: 536 FGS 544
F S
Sbjct: 169 FSS 171
>X66403-1|CAA47030.1| 493|Homo sapiens acetylcholine receptor
epsilon subunit CHRNE protein.
Length = 493
Score = 54.4 bits (125), Expect = 5e-07
Identities = 33/125 (26%), Positives = 63/125 (50%), Gaps = 3/125 (2%)
Frame = +2
Query: 182 PDSKIVVNLTLHLRHA-NIRESESTVRIQADLQMNWIDKRLSWNAGEWG-CSTWLVSSER 355
P+ + ++L + L + ++ E E T+ + ++W D RL+++ ++G T V SE
Sbjct: 45 PEDTVTISLKVTLTNLISLNEKEETLTTSVWIGIDWQDYRLNYSKDDFGGIETLRVPSEL 104
Query: 356 LWRPDVVLLNAAATTAG-DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTF 532
+W P++VL N G Y V GSV+W+ + ++++ +P D Q C+
Sbjct: 105 VWLPEIVLENNIDGQFGVAYDANVLVYEGGSVTWLPPAIYRSVCAVEVTYFPFDWQNCSL 164
Query: 533 KFGSR 547
F S+
Sbjct: 165 IFRSQ 169
>AF105999-1|AAD24503.1| 493|Homo sapiens acetylcholine receptor
epsilon subunit protein.
Length = 493
Score = 54.4 bits (125), Expect = 5e-07
Identities = 33/125 (26%), Positives = 63/125 (50%), Gaps = 3/125 (2%)
Frame = +2
Query: 182 PDSKIVVNLTLHLRHA-NIRESESTVRIQADLQMNWIDKRLSWNAGEWG-CSTWLVSSER 355
P+ + ++L + L + ++ E E T+ + ++W D RL+++ ++G T V SE
Sbjct: 45 PEDTVTISLKVTLTNLISLNEKEETLTTSVWIGIDWQDYRLNYSKDDFGGIETLRVPSEL 104
Query: 356 LWRPDVVLLNAAATTAG-DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTF 532
+W P++VL N G Y V GSV+W+ + ++++ +P D Q C+
Sbjct: 105 VWLPEIVLENNIDGQFGVAYDANVLVYEGGSVTWLPPAIYRSVCAVEVTYFPFDWQNCSL 164
Query: 533 KFGSR 547
F S+
Sbjct: 165 IFRSQ 169
>DQ644022-1|ABG35128.1| 456|Homo sapiens 5-HT3 receptor subunit E
splice variant HTR3Ea protein.
Length = 456
Score = 52.4 bits (120), Expect = 2e-06
Identities = 26/92 (28%), Positives = 46/92 (50%), Gaps = 1/92 (1%)
Frame = +2
Query: 272 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 448
L+M W + +SWN E G + ++++ LW PD+ ++ L A VSN G +
Sbjct: 91 LEMVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEGRI 150
Query: 449 SWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 544
+ K + + + ++ + +P D Q CT F S
Sbjct: 151 RYKKPMKVDSICNLDIFYFPFDQQNCTLTFSS 182
>BC101185-1|AAI01186.1| 374|Homo sapiens HTR3E protein protein.
Length = 374
Score = 52.4 bits (120), Expect = 2e-06
Identities = 26/92 (28%), Positives = 46/92 (50%), Gaps = 1/92 (1%)
Frame = +2
Query: 272 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 448
L+M W + +SWN E G + ++++ LW PD+ ++ L A VSN G +
Sbjct: 20 LEMVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEGRI 79
Query: 449 SWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 544
+ K + + + ++ + +P D Q CT F S
Sbjct: 80 RYKKPMKVDSICNLDIFYFPFDQQNCTLTFSS 111
>BC101183-1|AAI01184.1| 471|Homo sapiens 5-hydroxytryptamine
(serotonin) receptor 3, family member E protein.
Length = 471
Score = 52.4 bits (120), Expect = 2e-06
Identities = 26/92 (28%), Positives = 46/92 (50%), Gaps = 1/92 (1%)
Frame = +2
Query: 272 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 448
L+M W + +SWN E G + ++++ LW PD+ ++ L A VSN G +
Sbjct: 106 LEMVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEGRI 165
Query: 449 SWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 544
+ K + + + ++ + +P D Q CT F S
Sbjct: 166 RYKKPMKVDSICNLDIFYFPFDQQNCTLTFSS 197
>BC101182-1|AAI01183.1| 471|Homo sapiens 5-hydroxytryptamine
(serotonin) receptor 3, family member E protein.
Length = 471
Score = 52.4 bits (120), Expect = 2e-06
Identities = 26/92 (28%), Positives = 46/92 (50%), Gaps = 1/92 (1%)
Frame = +2
Query: 272 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 448
L+M W + +SWN E G + ++++ LW PD+ ++ L A VSN G +
Sbjct: 106 LEMVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEGRI 165
Query: 449 SWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 544
+ K + + + ++ + +P D Q CT F S
Sbjct: 166 RYKKPMKVDSICNLDIFYFPFDQQNCTLTFSS 197
>AY159813-1|AAO38167.2| 471|Homo sapiens 5-hydroxytryptamine
serotonin receptor 3E protein.
Length = 471
Score = 52.4 bits (120), Expect = 2e-06
Identities = 26/92 (28%), Positives = 46/92 (50%), Gaps = 1/92 (1%)
Frame = +2
Query: 272 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 448
L+M W + +SWN E G + ++++ LW PD+ ++ L A VSN G +
Sbjct: 106 LEMVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEGRI 165
Query: 449 SWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 544
+ K + + + ++ + +P D Q CT F S
Sbjct: 166 RYKKPMKVDSICNLDIFYFPFDQQNCTLTFSS 197
>Z23141-1|CAA80672.1| 479|Homo sapiens cholinergic receptor,
nicotinic, alpha polypeptide 7 protein.
Length = 479
Score = 52.0 bits (119), Expect = 3e-06
Identities = 34/126 (26%), Positives = 61/126 (48%), Gaps = 2/126 (1%)
Frame = +2
Query: 173 DSPPDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSS 349
DS P + + +L+L L+ ++ E + LQM+W D L WN E+ G T
Sbjct: 24 DSQPLT-VYFSLSL-LQIMDVDEKNQVLTTNIWLQMSWTDHYLQWNVSEYPGVKTVRFPD 81
Query: 350 ERLWRPDVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTC 526
++W+PD++L N+A + V+++G ++ + + + +P D+Q C
Sbjct: 82 GQIWKPDILLYNSADERFDATFHTNVLVNSSGHCQYLPPGIFKSSCYIDVRWFPFDVQHC 141
Query: 527 TFKFGS 544
KFGS
Sbjct: 142 KLKFGS 147
>Y08420-1|CAA69697.1| 502|Homo sapiens nicotinic acetylcholine
receptor alpha7 subunit precursor protein.
Length = 502
Score = 52.0 bits (119), Expect = 3e-06
Identities = 34/126 (26%), Positives = 61/126 (48%), Gaps = 2/126 (1%)
Frame = +2
Query: 173 DSPPDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSS 349
DS P + + +L+L L+ ++ E + LQM+W D L WN E+ G T
Sbjct: 47 DSQPLT-VYFSLSL-LQIMDVDEKNQVLTTNIWLQMSWTDHYLQWNVSEYPGVKTVRFPD 104
Query: 350 ERLWRPDVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTC 526
++W+PD++L N+A + V+++G ++ + + + +P D+Q C
Sbjct: 105 GQIWKPDILLYNSADERFDATFHTNVLVNSSGHCQYLPPGIFKSSCYIDVRWFPFDVQHC 164
Query: 527 TFKFGS 544
KFGS
Sbjct: 165 KLKFGS 170
>X70297-1|CAA49778.1| 502|Homo sapiens neuronal nicotinic
acetylocholine receptor alpha-7 subunit protein.
Length = 502
Score = 52.0 bits (119), Expect = 3e-06
Identities = 34/126 (26%), Positives = 61/126 (48%), Gaps = 2/126 (1%)
Frame = +2
Query: 173 DSPPDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSS 349
DS P + + +L+L L+ ++ E + LQM+W D L WN E+ G T
Sbjct: 47 DSQPLT-VYFSLSL-LQIMDVDEKNQVLTTNIWLQMSWTDHYLQWNVSEYPGVKTVRFPD 104
Query: 350 ERLWRPDVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTC 526
++W+PD++L N+A + V+++G ++ + + + +P D+Q C
Sbjct: 105 GQIWKPDILLYNSADERFDATFHTNVLVNSSGHCQYLPPGIFKSSCYIDVRWFPFDVQHC 164
Query: 527 TFKFGS 544
KFGS
Sbjct: 165 KLKFGS 170
>U62436-1|AAB40114.1| 502|Homo sapiens nicotinic acetylcholine
receptor alpha7 subunit precursor protein.
Length = 502
Score = 52.0 bits (119), Expect = 3e-06
Identities = 34/126 (26%), Positives = 61/126 (48%), Gaps = 2/126 (1%)
Frame = +2
Query: 173 DSPPDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSS 349
DS P + + +L+L L+ ++ E + LQM+W D L WN E+ G T
Sbjct: 47 DSQPLT-VYFSLSL-LQIMDVDEKNQVLTTNIWLQMSWTDHYLQWNVSEYPGVKTVRFPD 104
Query: 350 ERLWRPDVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTC 526
++W+PD++L N+A + V+++G ++ + + + +P D+Q C
Sbjct: 105 GQIWKPDILLYNSADERFDATFHTNVLVNSSGHCQYLPPGIFKSSCYIDVRWFPFDVQHC 164
Query: 527 TFKFGS 544
KFGS
Sbjct: 165 KLKFGS 170
>AJ586911-1|CAE52911.1| 502|Homo sapiens nicotinic acetylcholine
alpha-7 subunit protein.
Length = 502
Score = 52.0 bits (119), Expect = 3e-06
Identities = 34/126 (26%), Positives = 61/126 (48%), Gaps = 2/126 (1%)
Frame = +2
Query: 173 DSPPDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSS 349
DS P + + +L+L L+ ++ E + LQM+W D L WN E+ G T
Sbjct: 47 DSQPLT-VYFSLSL-LQIMDVDEKNQVLTTNIWLQMSWTDHYLQWNVSEYPGVKTVRFPD 104
Query: 350 ERLWRPDVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTC 526
++W+PD++L N+A + V+++G ++ + + + +P D+Q C
Sbjct: 105 GQIWKPDILLYNSADERFDATFHTNVLVNSSGHCQYLPPGIFKSSCYIDVRWFPFDVQHC 164
Query: 527 TFKFGS 544
KFGS
Sbjct: 165 KLKFGS 170
>AJ295237-1|CAC16144.1| 450|Homo sapiens neuronal nicotinic
acetylcholine receptor subunit4 protein.
Length = 450
Score = 52.0 bits (119), Expect = 3e-06
Identities = 43/156 (27%), Positives = 67/156 (42%), Gaps = 10/156 (6%)
Frame = +2
Query: 107 AEC---ENATSLSLMIDSLLATYDRDSPP--DSKIVVNLTLHLRHANI---RESESTVRI 262
AEC E +L L D L A Y P D+ +N+TL + + I E + +
Sbjct: 20 AECLGAEGRLALKLFRD-LFANYTSALRPVADTDQTLNVTLEVTLSQIIDMDERNQVLTL 78
Query: 263 QADLQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSN 436
++ W D L W+ +G + S +WRPD+VL N A A G + + +
Sbjct: 79 YLWIRQEWTDAYLRWDPNAYGGLDAIRIPSSLVWRPDIVLYNKADAQPPGSASTNVVLRH 138
Query: 437 NGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 544
+G+V W + + + +P D Q C FGS
Sbjct: 139 DGAVRWDAPAITRSSCRVDVAAFPFDAQHCGLTFGS 174
>AJ278118-1|CAC20435.1| 450|Homo sapiens neuronal nicotinic
acetylcholine alpha10 subunit protein.
Length = 450
Score = 52.0 bits (119), Expect = 3e-06
Identities = 43/156 (27%), Positives = 67/156 (42%), Gaps = 10/156 (6%)
Frame = +2
Query: 107 AEC---ENATSLSLMIDSLLATYDRDSPP--DSKIVVNLTLHLRHANI---RESESTVRI 262
AEC E +L L D L A Y P D+ +N+TL + + I E + +
Sbjct: 20 AECLGAEGRLALKLFRD-LFANYTSALRPVADTDQTLNVTLEVTLSQIIDMDERNQVLTL 78
Query: 263 QADLQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSN 436
++ W D L W+ +G + S +WRPD+VL N A A G + + +
Sbjct: 79 YLWIRQEWTDAYLRWDPNAYGGLDAIRIPSSLVWRPDIVLYNKADAQPPGSASTNVVLRH 138
Query: 437 NGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 544
+G+V W + + + +P D Q C FGS
Sbjct: 139 DGAVRWDAPAITRSSCRVDVAAFPFDAQHCGLTFGS 174
>AF327367-1|AAK14333.1| 450|Homo sapiens nicotinic acetylcholine
receptor subunit alpha 10 protein.
Length = 450
Score = 52.0 bits (119), Expect = 3e-06
Identities = 43/156 (27%), Positives = 67/156 (42%), Gaps = 10/156 (6%)
Frame = +2
Query: 107 AEC---ENATSLSLMIDSLLATYDRDSPP--DSKIVVNLTLHLRHANI---RESESTVRI 262
AEC E +L L D L A Y P D+ +N+TL + + I E + +
Sbjct: 20 AECLGAEGRLALKLFRD-LFANYTSALRPVADTDQTLNVTLEVTLSQIIDMDERNQVLTL 78
Query: 263 QADLQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSN 436
++ W D L W+ +G + S +WRPD+VL N A A G + + +
Sbjct: 79 YLWIRQEWTDAYLRWDPNAYGGLDAIRIPSSLVWRPDIVLYNKADAQPPGSASTNVVLRH 138
Query: 437 NGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 544
+G+V W + + + +P D Q C FGS
Sbjct: 139 DGAVRWDAPAITRSSCRVDVAAFPFDAQHCGLTFGS 174
>AF199235-1|AAG00795.2| 450|Homo sapiens nicotinic acetylcholine
receptor subunit alpha 10 protein.
Length = 450
Score = 52.0 bits (119), Expect = 3e-06
Identities = 43/156 (27%), Positives = 67/156 (42%), Gaps = 10/156 (6%)
Frame = +2
Query: 107 AEC---ENATSLSLMIDSLLATYDRDSPP--DSKIVVNLTLHLRHANI---RESESTVRI 262
AEC E +L L D L A Y P D+ +N+TL + + I E + +
Sbjct: 20 AECLGAEGRLALKLFRD-LFANYTSALRPVADTDQTLNVTLEVTLSQIIDMDERNQVLTL 78
Query: 263 QADLQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSN 436
++ W D L W+ +G + S +WRPD+VL N A A G + + +
Sbjct: 79 YLWIRQEWTDAYLRWDPNAYGGLDAIRIPSSLVWRPDIVLYNKADAQPPGSASTNVVLRH 138
Query: 437 NGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 544
+G+V W + + + +P D Q C FGS
Sbjct: 139 DGAVRWDAPAITRSSCRVDVAAFPFDAQHCGLTFGS 174
>L08485-1|AAA58490.1| 462|Homo sapiens GABA-benzodiazepine receptor
alpha-5-subunit protein.
Length = 462
Score = 51.6 bits (118), Expect = 4e-06
Identities = 37/150 (24%), Positives = 67/150 (44%), Gaps = 7/150 (4%)
Frame = +2
Query: 116 ENATSLSLMIDSLLATYDRDSPPD--SKIV-VNLTLHLRHAN-IRESESTVRIQADLQMN 283
+N T + ++D LL YD P +I V +++ + ++E I + +
Sbjct: 44 DNITIFTRILDGLLDGYDNRLRPGLGERITQVRTDIYVTSFGPVSDTEMEYTIDVFFRQS 103
Query: 284 WIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSW 454
W D+RL + + + ++W PD N + A + R+ ++G++ +
Sbjct: 104 WKDERLRFKGPMQRLPLNNLLASKIWTPDTFFHNGKKSIAHNMTTPNKLLRLEDDGTLLY 163
Query: 455 IKRLDISTPISMQLDNWPNDMQTCTFKFGS 544
RL IS MQL+++P D C KFGS
Sbjct: 164 TMRLTISAECPMQLEDFPMDAHACPLKFGS 193
>BT009830-1|AAP88832.1| 462|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 5 protein.
Length = 462
Score = 51.6 bits (118), Expect = 4e-06
Identities = 37/150 (24%), Positives = 67/150 (44%), Gaps = 7/150 (4%)
Frame = +2
Query: 116 ENATSLSLMIDSLLATYDRDSPPD--SKIV-VNLTLHLRHAN-IRESESTVRIQADLQMN 283
+N T + ++D LL YD P +I V +++ + ++E I + +
Sbjct: 44 DNITIFTRILDGLLDGYDNRLRPGLGERITQVRTDIYVTSFGPVSDTEMEYTIDVFFRQS 103
Query: 284 WIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSW 454
W D+RL + + + ++W PD N + A + R+ ++G++ +
Sbjct: 104 WKDERLRFKGPMQRLPLNNLLASKIWTPDTFFHNGKKSIAHNMTTPNKLLRLEDDGTLLY 163
Query: 455 IKRLDISTPISMQLDNWPNDMQTCTFKFGS 544
RL IS MQL+++P D C KFGS
Sbjct: 164 TMRLTISAECPMQLEDFPMDAHACPLKFGS 193
>BC113422-1|AAI13423.1| 462|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 5 protein.
Length = 462
Score = 51.6 bits (118), Expect = 4e-06
Identities = 37/150 (24%), Positives = 67/150 (44%), Gaps = 7/150 (4%)
Frame = +2
Query: 116 ENATSLSLMIDSLLATYDRDSPPD--SKIV-VNLTLHLRHAN-IRESESTVRIQADLQMN 283
+N T + ++D LL YD P +I V +++ + ++E I + +
Sbjct: 44 DNITIFTRILDGLLDGYDNRLRPGLGERITQVRTDIYVTSFGPVSDTEMEYTIDVFFRQS 103
Query: 284 WIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSW 454
W D+RL + + + ++W PD N + A + R+ ++G++ +
Sbjct: 104 WKDERLRFKGPMQRLPLNNLLASKIWTPDTFFHNGKKSIAHNMTTPNKLLRLEDDGTLLY 163
Query: 455 IKRLDISTPISMQLDNWPNDMQTCTFKFGS 544
RL IS MQL+++P D C KFGS
Sbjct: 164 TMRLTISAECPMQLEDFPMDAHACPLKFGS 193
>BC111979-1|AAI11980.1| 462|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 5, precursor protein.
Length = 462
Score = 51.6 bits (118), Expect = 4e-06
Identities = 37/150 (24%), Positives = 67/150 (44%), Gaps = 7/150 (4%)
Frame = +2
Query: 116 ENATSLSLMIDSLLATYDRDSPPD--SKIV-VNLTLHLRHAN-IRESESTVRIQADLQMN 283
+N T + ++D LL YD P +I V +++ + ++E I + +
Sbjct: 44 DNITIFTRILDGLLDGYDNRLRPGLGERITQVRTDIYVTSFGPVSDTEMEYTIDVFFRQS 103
Query: 284 WIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSW 454
W D+RL + + + ++W PD N + A + R+ ++G++ +
Sbjct: 104 WKDERLRFKGPMQRLPLNNLLASKIWTPDTFFHNGKKSIAHNMTTPNKLLRLEDDGTLLY 163
Query: 455 IKRLDISTPISMQLDNWPNDMQTCTFKFGS 544
RL IS MQL+++P D C KFGS
Sbjct: 164 TMRLTISAECPMQLEDFPMDAHACPLKFGS 193
>BC111802-1|AAI11803.1| 465|Homo sapiens CHRNG protein protein.
Length = 465
Score = 51.2 bits (117), Expect = 5e-06
Identities = 33/113 (29%), Positives = 55/113 (48%), Gaps = 7/113 (6%)
Frame = +2
Query: 140 MIDSLLATYDRDSPPDSKI--VVNLTLHLRHANI---RESESTVRIQADLQMNWIDKRLS 304
++ L+ YD + P + VVN++L L N+ E E + ++M W D RL
Sbjct: 29 LLADLMQNYDPNLRPAERDSDVVNVSLKLTLTNLISLNEREEALTTNVWIEMQWCDYRLR 88
Query: 305 WNAGEW-GCSTWLVSSERLWRPDVVLLNAAAT-TAGDYALRARVSNNGSVSWI 457
W+ ++ G V S +WRPD+VL N + T + + L+ + S+ WI
Sbjct: 89 WDPRDYEGLWVLRVPSTMVWRPDIVLENKSQTYSTNEIDLQLSQEDGQSIEWI 141
>BC131799-1|AAI31800.1| 447|Homo sapiens 5-hydroxytryptamine
(serotonin) receptor 3, family member C protein.
Length = 447
Score = 50.8 bits (116), Expect = 6e-06
Identities = 24/92 (26%), Positives = 47/92 (51%), Gaps = 1/92 (1%)
Frame = +2
Query: 272 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 448
+ + W + ++WN E G + V +E LW PD+ ++ + L A +S+ G +
Sbjct: 91 MDLVWDNPFINWNPKECVGINKLTVLAENLWLPDIFIVESMDVDQTPSGLTAYISSEGRI 150
Query: 449 SWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 544
+ K + +++ ++ + +P D Q CTF F S
Sbjct: 151 KYDKPMRVTSICNLDIFYFPFDQQNCTFTFSS 182
>BC113575-1|AAI13576.1| 479|Homo sapiens cholinergic receptor,
nicotinic, alpha 9 protein.
Length = 479
Score = 50.8 bits (116), Expect = 6e-06
Identities = 36/154 (23%), Positives = 69/154 (44%), Gaps = 7/154 (4%)
Frame = +2
Query: 104 AAECENATSLSLMIDSLLATYDRDSPP--DSKIVVNLTLHLRHANIRESESTVRIQAD-- 271
AAE + + + L Y P D+ V+N+TL + + I++ + +I
Sbjct: 22 AAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQITLSQIKDMDERNQILTAYL 81
Query: 272 -LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGD-YALRARVSNNG 442
++ W D L+W+ ++ G + + S+ +WRPD+VL N A + + + +G
Sbjct: 82 WIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKADDESSEPVNTNVVLRYDG 141
Query: 443 SVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 544
++W + + + +P D Q C FGS
Sbjct: 142 LITWDAPAITKSSCVVDVTYFPFDNQQCNLTFGS 175
>BC113549-1|AAI13550.1| 479|Homo sapiens cholinergic receptor,
nicotinic, alpha 9 protein.
Length = 479
Score = 50.8 bits (116), Expect = 6e-06
Identities = 36/154 (23%), Positives = 69/154 (44%), Gaps = 7/154 (4%)
Frame = +2
Query: 104 AAECENATSLSLMIDSLLATYDRDSPP--DSKIVVNLTLHLRHANIRESESTVRIQAD-- 271
AAE + + + L Y P D+ V+N+TL + + I++ + +I
Sbjct: 22 AAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQITLSQIKDMDERNQILTAYL 81
Query: 272 -LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGD-YALRARVSNNG 442
++ W D L+W+ ++ G + + S+ +WRPD+VL N A + + + +G
Sbjct: 82 WIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKADDESSEPVNTNVVLRYDG 141
Query: 443 SVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 544
++W + + + +P D Q C FGS
Sbjct: 142 LITWDAPAITKSSCVVDVTYFPFDNQQCNLTFGS 175
>BC110597-1|AAI10598.1| 411|Homo sapiens ligand-gated ion channel,
zinc activated 1 protein.
Length = 411
Score = 50.8 bits (116), Expect = 6e-06
Identities = 26/89 (29%), Positives = 42/89 (47%)
Frame = +2
Query: 272 LQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVS 451
L+++W+D RL+WN + E LW P + +L A D + +ARV +G V
Sbjct: 86 LRLSWLDTRLAWNTSAHPRHAITLPWESLWTPRLTILEALWVDWRDQSPQARVDQDGHVK 145
Query: 452 WIKRLDISTPISMQLDNWPNDMQTCTFKF 538
L T + +L ++P D C+ F
Sbjct: 146 LNLALTTETNCNFELLHFPRDHSNCSLSF 174
>AY349353-1|AAQ93477.1| 456|Homo sapiens 5-HT3c1 serotonin
receptor-like protein protein.
Length = 456
Score = 50.8 bits (116), Expect = 6e-06
Identities = 26/96 (27%), Positives = 47/96 (48%), Gaps = 1/96 (1%)
Frame = +2
Query: 260 IQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSN 436
+ A L + W + +SWN E G + ++++ LW PD+ ++ L A VSN
Sbjct: 87 MSAILDVVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSN 146
Query: 437 NGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 544
G + + K + + + ++ + +P D Q CT F S
Sbjct: 147 EGRIRYKKPMKVDSICNLDIFYFPFDQQNCTLTFSS 182
>AY349352-1|AAQ93476.1| 441|Homo sapiens 5-HT3c1 serotonin
receptor-like protein protein.
Length = 441
Score = 50.8 bits (116), Expect = 6e-06
Identities = 26/96 (27%), Positives = 47/96 (48%), Gaps = 1/96 (1%)
Frame = +2
Query: 260 IQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSN 436
+ A L + W + +SWN E G + ++++ LW PD+ ++ L A VSN
Sbjct: 72 MSAILDVVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSN 131
Query: 437 NGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 544
G + + K + + + ++ + +P D Q CT F S
Sbjct: 132 EGRIRYKKPMKVDSICNLDIFYFPFDQQNCTLTFSS 167
>AY123244-1|AAM74523.1| 479|Homo sapiens nicotinic acetylcholine
receptor subunit alpha 9 protein.
Length = 479
Score = 50.8 bits (116), Expect = 6e-06
Identities = 36/154 (23%), Positives = 69/154 (44%), Gaps = 7/154 (4%)
Frame = +2
Query: 104 AAECENATSLSLMIDSLLATYDRDSPP--DSKIVVNLTLHLRHANIRESESTVRIQAD-- 271
AAE + + + L Y P D+ V+N+TL + + I++ + +I
Sbjct: 22 AAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQITLSQIKDMDERNQILTAYL 81
Query: 272 -LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGD-YALRARVSNNG 442
++ W D L+W+ ++ G + + S+ +WRPD+VL N A + + + +G
Sbjct: 82 WIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKADDESSEPVNTNVVLRYDG 141
Query: 443 SVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 544
++W + + + +P D Q C FGS
Sbjct: 142 LITWDAPAITKSSCVVDVTYFPFDNQQCNLTFGS 175
>AK122638-1|BAC85499.1| 266|Homo sapiens yte protein of 76kDa)
(LCP2). protein.
Length = 266
Score = 50.8 bits (116), Expect = 6e-06
Identities = 26/89 (29%), Positives = 42/89 (47%)
Frame = +2
Query: 272 LQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVS 451
L+++W+D RL+WN + E LW P + +L A D + +ARV +G V
Sbjct: 87 LRLSWLDTRLAWNTSAHPRHAITLPWESLWTPRLTILEALWVDWRDQSPQARVDQDGHVK 146
Query: 452 WIKRLDISTPISMQLDNWPNDMQTCTFKF 538
L T + +L ++P D C+ F
Sbjct: 147 LNLALTTETNCNFELLHFPRDHSNCSLSF 175
>AJ243342-1|CAB65091.1| 479|Homo sapiens nicotinic acetylcholine
receptor alpha 9 subunit protein.
Length = 479
Score = 50.8 bits (116), Expect = 6e-06
Identities = 36/154 (23%), Positives = 69/154 (44%), Gaps = 7/154 (4%)
Frame = +2
Query: 104 AAECENATSLSLMIDSLLATYDRDSPP--DSKIVVNLTLHLRHANIRESESTVRIQAD-- 271
AAE + + + L Y P D+ V+N+TL + + I++ + +I
Sbjct: 22 AAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQITLSQIKDMDERNQILTAYL 81
Query: 272 -LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGD-YALRARVSNNG 442
++ W D L+W+ ++ G + + S+ +WRPD+VL N A + + + +G
Sbjct: 82 WIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKADDESSEPVNTNVVLRYDG 141
Query: 443 SVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 544
++W + + + +P D Q C FGS
Sbjct: 142 LITWDAPAITKSSCVVDVTYFPFDNQQCNLTFGS 175
>AF512521-1|AAO20969.1| 411|Homo sapiens ligand-gated ion channel
subunit protein.
Length = 411
Score = 50.8 bits (116), Expect = 6e-06
Identities = 26/89 (29%), Positives = 42/89 (47%)
Frame = +2
Query: 272 LQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVS 451
L+++W+D RL+WN + E LW P + +L A D + +ARV +G V
Sbjct: 86 LRLSWLDTRLAWNTSAHPRHAITLPWESLWTPRLTILEALWVDWRDQSPQARVDQDGHVK 145
Query: 452 WIKRLDISTPISMQLDNWPNDMQTCTFKF 538
L T + +L ++P D C+ F
Sbjct: 146 LNLALTTETNCNFELLHFPRDHSNCSLSF 174
>AF227732-1|AAF61920.1| 470|Homo sapiens nicotinic acetylcholine
receptor alpha 9 subunit protein.
Length = 470
Score = 50.8 bits (116), Expect = 6e-06
Identities = 36/154 (23%), Positives = 69/154 (44%), Gaps = 7/154 (4%)
Frame = +2
Query: 104 AAECENATSLSLMIDSLLATYDRDSPP--DSKIVVNLTLHLRHANIRESESTVRIQAD-- 271
AAE + + + L Y P D+ V+N+TL + + I++ + +I
Sbjct: 16 AAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQITLSQIKDMDERNQILTAYL 75
Query: 272 -LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGD-YALRARVSNNG 442
++ W D L+W+ ++ G + + S+ +WRPD+VL N A + + + +G
Sbjct: 76 WIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKADDESSEPVNTNVVLRYDG 135
Query: 443 SVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 544
++W + + + +P D Q C FGS
Sbjct: 136 LITWDAPAITKSSCVVDVTYFPFDNQQCNLTFGS 169
>AC118275-1|AAY40986.1| 479|Homo sapiens unknown protein.
Length = 479
Score = 50.8 bits (116), Expect = 6e-06
Identities = 36/154 (23%), Positives = 69/154 (44%), Gaps = 7/154 (4%)
Frame = +2
Query: 104 AAECENATSLSLMIDSLLATYDRDSPP--DSKIVVNLTLHLRHANIRESESTVRIQAD-- 271
AAE + + + L Y P D+ V+N+TL + + I++ + +I
Sbjct: 22 AAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQITLSQIKDMDERNQILTAYL 81
Query: 272 -LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGD-YALRARVSNNG 442
++ W D L+W+ ++ G + + S+ +WRPD+VL N A + + + +G
Sbjct: 82 WIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKADDESSEPVNTNVVLRYDG 141
Query: 443 SVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 544
++W + + + +P D Q C FGS
Sbjct: 142 LITWDAPAITKSSCVVDVTYFPFDNQQCNLTFGS 175
>U40583-1|AAA83561.1| 502|Homo sapiens alpha 7 neuronal nicotinic
acetylcholine receptor protein.
Length = 502
Score = 50.4 bits (115), Expect = 8e-06
Identities = 34/126 (26%), Positives = 59/126 (46%), Gaps = 2/126 (1%)
Frame = +2
Query: 173 DSPPDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSS 349
DS P + + +L L L+ ++ E + LQM+W D L WN E+ G T
Sbjct: 47 DSQPLT-VYFSLNL-LQIMDVDEKNQVLTTNIWLQMSWTDHYLQWNVSEYPGVKTVRFPD 104
Query: 350 ERLWRPDVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTC 526
++W+PD++L N+A + V+ +G ++ + + + +P D+Q C
Sbjct: 105 GQIWKPDILLYNSADERFDATFHTNVLVNPSGHCQYLPPGIFKSSCYIDVRWFPFDVQHC 164
Query: 527 TFKFGS 544
KFGS
Sbjct: 165 KLKFGS 170
>BC028629-1|AAH28629.1| 492|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 3 protein.
Length = 492
Score = 50.4 bits (115), Expect = 8e-06
Identities = 35/150 (23%), Positives = 66/150 (44%), Gaps = 7/150 (4%)
Frame = +2
Query: 116 ENATSLSLMIDSLLATYDRDSPP---DSKIVVNLTLHLRHAN-IRESESTVRIQADLQMN 283
+N T + ++D LL YD P D+ V +++ + +++ I +
Sbjct: 62 DNITIFTRILDRLLDGYDNRLRPGLGDAVTEVKTDIYVTSFGPVSDTDMEYTIDVFFRQT 121
Query: 284 WIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSW 454
W D+RL ++ + + ++W PD N + A + R+ +NG++ +
Sbjct: 122 WHDERLKFDGPMKILPLNNLLASKIWTPDTFFHNGKKSVAHNMTTPNKLLRLVDNGTLPY 181
Query: 455 IKRLDISTPISMQLDNWPNDMQTCTFKFGS 544
RL I M L+++P D+ C KFGS
Sbjct: 182 TMRLTIHAECPMHLEDFPMDVHACPLKFGS 211
>AF459285-1|AAL66182.1| 447|Homo sapiens 5-hydroxytryptamine
receptor 3 subunit C protein.
Length = 447
Score = 50.4 bits (115), Expect = 8e-06
Identities = 24/92 (26%), Positives = 46/92 (50%), Gaps = 1/92 (1%)
Frame = +2
Query: 272 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 448
+ + W + ++WN E G + V +E LW PD+ ++ + L A +S+ G +
Sbjct: 91 MDLVWDNPFINWNPKECVGINKLTVLAENLWLPDIFIVESMDVDQTPSGLTAYISSEGRI 150
Query: 449 SWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 544
+ K + +++ + + +P D Q CTF F S
Sbjct: 151 KYDKPMRVTSICKLDIFYFPFDQQNCTFTFSS 182
>AF385585-1|AAK68111.1| 502|Homo sapiens nicotinic cholinergic
receptor alpha 7 protein.
Length = 502
Score = 50.4 bits (115), Expect = 8e-06
Identities = 34/126 (26%), Positives = 59/126 (46%), Gaps = 2/126 (1%)
Frame = +2
Query: 173 DSPPDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSS 349
DS P + + +L L L+ ++ E + LQM+W D L WN E+ G T
Sbjct: 47 DSQPLT-VYFSLNL-LQIMDVDEKNQVLTTNIWLQMSWTDHYLQWNVSEYPGVKTVRFPD 104
Query: 350 ERLWRPDVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTC 526
++W+PD++L N+A + V+ +G ++ + + + +P D+Q C
Sbjct: 105 GQIWKPDILLYNSADERFDATFHTNVLVNPSGHCQYLPPGIFKSSCYIDVRWFPFDVQHC 164
Query: 527 TFKFGS 544
KFGS
Sbjct: 165 KLKFGS 170
>AB223030-1|BAE19924.1| 411|Homo sapiens ligand-gated ion-channel
receptor L2 protein.
Length = 411
Score = 50.4 bits (115), Expect = 8e-06
Identities = 26/89 (29%), Positives = 42/89 (47%)
Frame = +2
Query: 272 LQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVS 451
L+++W+D RL+WN + E LW P + +L A D + +ARV +G V
Sbjct: 86 LRLSWLDTRLAWNTSAHPRHAITLPWESLWTPRLTILEALWVDWRDQSPQARVDQDGHVK 145
Query: 452 WIKRLDISTPISMQLDNWPNDMQTCTFKF 538
L T + +L ++P D C+ F
Sbjct: 146 LNLALATETNCNFELLHFPRDHSNCSLSF 174
>S62908-1|AAB27279.1| 492|Homo sapiens gamma-aminobutyric acidA
receptor alpha 3 subunit protein.
Length = 492
Score = 50.0 bits (114), Expect = 1e-05
Identities = 35/150 (23%), Positives = 66/150 (44%), Gaps = 7/150 (4%)
Frame = +2
Query: 116 ENATSLSLMIDSLLATYDRDSPP---DSKIVVNLTLHLRHAN-IRESESTVRIQADLQMN 283
+N T + ++D LL YD P D+ V +++ + +++ I +
Sbjct: 62 DNITIFTRILDRLLDGYDNRLRPGLGDAVTEVKTDIYVTSFGPVSDTDMEYTIDVFFRQT 121
Query: 284 WIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSW 454
W D+RL ++ + + ++W PD N + A + R+ +NG++ +
Sbjct: 122 WHDERLKFDGPMKILPLNNLLASKIWTPDTFFHNGKKSVAHNMTTPNKLLRLVDNGTLLY 181
Query: 455 IKRLDISTPISMQLDNWPNDMQTCTFKFGS 544
RL I M L+++P D+ C KFGS
Sbjct: 182 TMRLTIHAECPMHLEDFPMDVHACPLKFGS 211
>AF166361-1|AAG12455.1| 492|Homo sapiens GABA receptor subunit
alpha 3 protein.
Length = 492
Score = 50.0 bits (114), Expect = 1e-05
Identities = 35/150 (23%), Positives = 66/150 (44%), Gaps = 7/150 (4%)
Frame = +2
Query: 116 ENATSLSLMIDSLLATYDRDSPP---DSKIVVNLTLHLRHAN-IRESESTVRIQADLQMN 283
+N T + ++D LL YD P D+ V +++ + +++ I +
Sbjct: 62 DNITIFTRILDRLLDGYDNRLRPGLGDAVTEVKTDIYVTSFGPVSDTDMEYTIDVFFRQT 121
Query: 284 WIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSW 454
W D+RL ++ + + ++W PD N + A + R+ +NG++ +
Sbjct: 122 WHDERLKFDGPMKILPLNNLLASKIWTPDTFFHNGKKSVAHNMTTPNKLLRLVDNGTLLY 181
Query: 455 IKRLDISTPISMQLDNWPNDMQTCTFKFGS 544
RL I M L+++P D+ C KFGS
Sbjct: 182 TMRLTIHAECPMHLEDFPMDVHACPLKFGS 211
>U77731-2|AAB38273.1| 360|Homo sapiens glycine receptor alpha 2B
subunit protein.
Length = 360
Score = 49.2 bits (112), Expect = 2e-05
Identities = 33/125 (26%), Positives = 55/125 (44%), Gaps = 4/125 (3%)
Frame = +2
Query: 182 PDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERL 358
P + N+ ++ +I E+ R+ L+ W D RL+++ S + +
Sbjct: 69 PPVNVTCNIFIN-SFGSIAETTMDYRVNIFLRQQWNDSRLAYSEYPDDSLDLDPSMLDSI 127
Query: 359 WRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCT 529
W+PD+ N D R+S NG V + RL ++ M L N+P D+QTCT
Sbjct: 128 WKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNFPMDVQTCT 187
Query: 530 FKFGS 544
+ S
Sbjct: 188 MQLES 192
>CR450343-1|CAG29339.1| 452|Homo sapiens GLRA2 protein.
Length = 452
Score = 49.2 bits (112), Expect = 2e-05
Identities = 33/125 (26%), Positives = 55/125 (44%), Gaps = 4/125 (3%)
Frame = +2
Query: 182 PDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERL 358
P + N+ ++ +I E+ R+ L+ W D RL+++ S + +
Sbjct: 69 PPVNVTCNIFIN-SFGSIAETTMDYRVNIFLRQQWNDSRLAYSEYPDDSLDLDPSMLDSI 127
Query: 359 WRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCT 529
W+PD+ N D R+S NG V + RL ++ M L N+P D+QTCT
Sbjct: 128 WKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNFPMDVQTCT 187
Query: 530 FKFGS 544
+ S
Sbjct: 188 MQLES 192
>AY437084-1|AAR87843.1| 452|Homo sapiens glycine receptor alpha2
subunit B protein.
Length = 452
Score = 49.2 bits (112), Expect = 2e-05
Identities = 33/125 (26%), Positives = 55/125 (44%), Gaps = 4/125 (3%)
Frame = +2
Query: 182 PDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERL 358
P + N+ ++ +I E+ R+ L+ W D RL+++ S + +
Sbjct: 69 PPVNVTCNIFIN-SFGSIAETTMDYRVNIFLRQQWNDSRLAYSEYPDDSLDLDPSMLDSI 127
Query: 359 WRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCT 529
W+PD+ N D R+S NG V + RL ++ M L N+P D+QTCT
Sbjct: 128 WKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNFPMDVQTCT 187
Query: 530 FKFGS 544
+ S
Sbjct: 188 MQLES 192
>X52008-1|CAA36257.1| 452|Homo sapiens inhibitory glycine receptor
protein.
Length = 452
Score = 48.8 bits (111), Expect = 3e-05
Identities = 32/125 (25%), Positives = 55/125 (44%), Gaps = 4/125 (3%)
Frame = +2
Query: 182 PDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERL 358
P + N+ ++ ++ E+ R+ L+ W D RL+++ S + +
Sbjct: 69 PPVNVTCNIFIN-SFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPDDSLDLDPSMLDSI 127
Query: 359 WRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCT 529
W+PD+ N D R+S NG V + RL ++ M L N+P D+QTCT
Sbjct: 128 WKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNFPMDVQTCT 187
Query: 530 FKFGS 544
+ S
Sbjct: 188 MQLES 192
>U77731-1|AAB38272.1| 360|Homo sapiens glycine receptor alpha 2
subunit protein.
Length = 360
Score = 48.8 bits (111), Expect = 3e-05
Identities = 32/125 (25%), Positives = 55/125 (44%), Gaps = 4/125 (3%)
Frame = +2
Query: 182 PDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERL 358
P + N+ ++ ++ E+ R+ L+ W D RL+++ S + +
Sbjct: 69 PPVNVTCNIFIN-SFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPDDSLDLDPSMLDSI 127
Query: 359 WRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCT 529
W+PD+ N D R+S NG V + RL ++ M L N+P D+QTCT
Sbjct: 128 WKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNFPMDVQTCT 187
Query: 530 FKFGS 544
+ S
Sbjct: 188 MQLES 192
>BC032864-1|AAH32864.1| 452|Homo sapiens glycine receptor, alpha 2
protein.
Length = 452
Score = 48.8 bits (111), Expect = 3e-05
Identities = 32/125 (25%), Positives = 55/125 (44%), Gaps = 4/125 (3%)
Frame = +2
Query: 182 PDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERL 358
P + N+ ++ ++ E+ R+ L+ W D RL+++ S + +
Sbjct: 69 PPVNVTCNIFIN-SFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPDDSLDLDPSMLDSI 127
Query: 359 WRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCT 529
W+PD+ N D R+S NG V + RL ++ M L N+P D+QTCT
Sbjct: 128 WKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNFPMDVQTCT 187
Query: 530 FKFGS 544
+ S
Sbjct: 188 MQLES 192
>AY437083-1|AAR87842.1| 452|Homo sapiens glycine receptor alpha2
subunit A protein.
Length = 452
Score = 48.8 bits (111), Expect = 3e-05
Identities = 32/125 (25%), Positives = 55/125 (44%), Gaps = 4/125 (3%)
Frame = +2
Query: 182 PDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERL 358
P + N+ ++ ++ E+ R+ L+ W D RL+++ S + +
Sbjct: 69 PPVNVTCNIFIN-SFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPDDSLDLDPSMLDSI 127
Query: 359 WRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCT 529
W+PD+ N D R+S NG V + RL ++ M L N+P D+QTCT
Sbjct: 128 WKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNFPMDVQTCT 187
Query: 530 FKFGS 544
+ S
Sbjct: 188 MQLES 192
>AF053495-1|AAC35290.1| 452|Homo sapiens glycine receptor alpha 2
subunit protein.
Length = 452
Score = 48.8 bits (111), Expect = 3e-05
Identities = 32/125 (25%), Positives = 55/125 (44%), Gaps = 4/125 (3%)
Frame = +2
Query: 182 PDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERL 358
P + N+ ++ ++ E+ R+ L+ W D RL+++ S + +
Sbjct: 69 PPVNVTCNIFIN-SFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPDDSLDLDPSMLDSI 127
Query: 359 WRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCT 529
W+PD+ N D R+S NG V + RL ++ M L N+P D+QTCT
Sbjct: 128 WKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNFPMDVQTCT 187
Query: 530 FKFGS 544
+ S
Sbjct: 188 MQLES 192
>S81944-1|AAB36480.1| 453|Homo sapiens gamma-aminobutyric acid type
A receptor alpha 6 subunit protein.
Length = 453
Score = 48.0 bits (109), Expect = 4e-05
Identities = 35/146 (23%), Positives = 62/146 (42%), Gaps = 7/146 (4%)
Frame = +2
Query: 128 SLSLMIDSLLATYDRDSPPD---SKIVVNLTLHLRHAN-IRESESTVRIQADLQMNWIDK 295
++S ++D+LL YD P + V +++ + + E + + W D+
Sbjct: 31 NVSRILDNLLEGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTDE 90
Query: 296 RLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRA---RVSNNGSVSWIKRL 466
RL + S + ++W PD N + A + R+ NG++ + RL
Sbjct: 91 RLKFGGPTEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTMRL 150
Query: 467 DISTPISMQLDNWPNDMQTCTFKFGS 544
I+ M+L N+P D C KFGS
Sbjct: 151 TINADCPMRLVNFPMDGHACPLKFGS 176
>BC099641-1|AAH99641.1| 453|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 6 protein.
Length = 453
Score = 48.0 bits (109), Expect = 4e-05
Identities = 35/146 (23%), Positives = 62/146 (42%), Gaps = 7/146 (4%)
Frame = +2
Query: 128 SLSLMIDSLLATYDRDSPPD---SKIVVNLTLHLRHAN-IRESESTVRIQADLQMNWIDK 295
++S ++D+LL YD P + V +++ + + E + + W D+
Sbjct: 31 NVSRILDNLLEGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTDE 90
Query: 296 RLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRA---RVSNNGSVSWIKRL 466
RL + S + ++W PD N + A + R+ NG++ + RL
Sbjct: 91 RLKFGGPTEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTMRL 150
Query: 467 DISTPISMQLDNWPNDMQTCTFKFGS 544
I+ M+L N+P D C KFGS
Sbjct: 151 TINADCPMRLVNFPMDGHACPLKFGS 176
>BC099640-1|AAH99640.1| 453|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 6 protein.
Length = 453
Score = 48.0 bits (109), Expect = 4e-05
Identities = 35/146 (23%), Positives = 62/146 (42%), Gaps = 7/146 (4%)
Frame = +2
Query: 128 SLSLMIDSLLATYDRDSPPD---SKIVVNLTLHLRHAN-IRESESTVRIQADLQMNWIDK 295
++S ++D+LL YD P + V +++ + + E + + W D+
Sbjct: 31 NVSRILDNLLEGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTDE 90
Query: 296 RLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRA---RVSNNGSVSWIKRL 466
RL + S + ++W PD N + A + R+ NG++ + RL
Sbjct: 91 RLKFGGPTEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTMRL 150
Query: 467 DISTPISMQLDNWPNDMQTCTFKFGS 544
I+ M+L N+P D C KFGS
Sbjct: 151 TINADCPMRLVNFPMDGHACPLKFGS 176
>BC096242-1|AAH96242.1| 453|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 6 protein.
Length = 453
Score = 48.0 bits (109), Expect = 4e-05
Identities = 35/146 (23%), Positives = 62/146 (42%), Gaps = 7/146 (4%)
Frame = +2
Query: 128 SLSLMIDSLLATYDRDSPPD---SKIVVNLTLHLRHAN-IRESESTVRIQADLQMNWIDK 295
++S ++D+LL YD P + V +++ + + E + + W D+
Sbjct: 31 NVSRILDNLLEGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTDE 90
Query: 296 RLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRA---RVSNNGSVSWIKRL 466
RL + S + ++W PD N + A + R+ NG++ + RL
Sbjct: 91 RLKFGGPTEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTMRL 150
Query: 467 DISTPISMQLDNWPNDMQTCTFKFGS 544
I+ M+L N+P D C KFGS
Sbjct: 151 TINADCPMRLVNFPMDGHACPLKFGS 176
>BC096241-1|AAH96241.1| 453|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 6 protein.
Length = 453
Score = 48.0 bits (109), Expect = 4e-05
Identities = 35/146 (23%), Positives = 62/146 (42%), Gaps = 7/146 (4%)
Frame = +2
Query: 128 SLSLMIDSLLATYDRDSPPD---SKIVVNLTLHLRHAN-IRESESTVRIQADLQMNWIDK 295
++S ++D+LL YD P + V +++ + + E + + W D+
Sbjct: 31 NVSRILDNLLEGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTDE 90
Query: 296 RLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRA---RVSNNGSVSWIKRL 466
RL + S + ++W PD N + A + R+ NG++ + RL
Sbjct: 91 RLKFGGPTEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTMRL 150
Query: 467 DISTPISMQLDNWPNDMQTCTFKFGS 544
I+ M+L N+P D C KFGS
Sbjct: 151 TINADCPMRLVNFPMDGHACPLKFGS 176
>S82769-1|AAB39369.1| 467|Homo sapiens GABAA receptor gamma 3
subunit protein.
Length = 467
Score = 47.6 bits (108), Expect = 6e-05
Identities = 35/147 (23%), Positives = 63/147 (42%), Gaps = 7/147 (4%)
Frame = +2
Query: 125 TSLSLMIDSLLATYDRDSPPDSKI---VVNLTLHLRHAN-IRESESTVRIQADLQMNWID 292
T ++L+++ LL YD+ PD I V+++ +++ + +I W D
Sbjct: 45 TDVTLILNKLLREYDKKLRPDIGIKPTVIDVDIYVNSIGPVSSINMEYQIDIFFAQTWTD 104
Query: 293 KRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKR 463
RL +N+ + +W PD + N+ A R+ N+G + + R
Sbjct: 105 SRLRFNSTMKILTLNSNMVGLIWIPDTIFRNSKTAEAHWITTPNQLLRIWNDGKILYTLR 164
Query: 464 LDISTPISMQLDNWPNDMQTCTFKFGS 544
L I+ +QL N+P D +C F S
Sbjct: 165 LTINAECQLQLHNFPMDEHSCPLIFSS 191
>BC096083-1|AAH96083.1| 198|Homo sapiens CHRNB4 protein protein.
Length = 198
Score = 47.6 bits (108), Expect = 6e-05
Identities = 30/115 (26%), Positives = 55/115 (47%), Gaps = 8/115 (6%)
Frame = +2
Query: 92 AIASAAECENATSLSLMIDSLL--ATYD---RDSPPDSKIV-VNLTLHLRHA-NIRESES 250
A+ C A + ++D LL Y+ R + S+++ + L L L ++ E E
Sbjct: 14 ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQ 73
Query: 251 TVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDY 412
+ L+ W D RL+WN+ + G + + ++R+W PD+VL N + T +
Sbjct: 74 IMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNKSLRTGSTW 128
>BC096081-1|AAH96081.1| 198|Homo sapiens CHRNB4 protein protein.
Length = 198
Score = 47.6 bits (108), Expect = 6e-05
Identities = 30/115 (26%), Positives = 55/115 (47%), Gaps = 8/115 (6%)
Frame = +2
Query: 92 AIASAAECENATSLSLMIDSLL--ATYD---RDSPPDSKIV-VNLTLHLRHA-NIRESES 250
A+ C A + ++D LL Y+ R + S+++ + L L L ++ E E
Sbjct: 14 ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQ 73
Query: 251 TVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDY 412
+ L+ W D RL+WN+ + G + + ++R+W PD+VL N + T +
Sbjct: 74 IMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNKSLRTGSTW 128
>AF269144-1|AAF99698.1| 467|Homo sapiens GABAA receptor gamma 3
subunit protein.
Length = 467
Score = 47.6 bits (108), Expect = 6e-05
Identities = 35/147 (23%), Positives = 63/147 (42%), Gaps = 7/147 (4%)
Frame = +2
Query: 125 TSLSLMIDSLLATYDRDSPPDSKI---VVNLTLHLRHAN-IRESESTVRIQADLQMNWID 292
T ++L+++ LL YD+ PD I V+++ +++ + +I W D
Sbjct: 45 TDVTLILNKLLREYDKKLRPDIGIKPTVIDVDIYVNSIGPVSSINMEYQIDIFFAQTWTD 104
Query: 293 KRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKR 463
RL +N+ + +W PD + N+ A R+ N+G + + R
Sbjct: 105 SRLRFNSTMKILTLNSNMVGLIWIPDTIFRNSKTAEAHWITTPNQLLRIWNDGKILYTLR 164
Query: 464 LDISTPISMQLDNWPNDMQTCTFKFGS 544
L I+ +QL N+P D +C F S
Sbjct: 165 LTINAECQLQLHNFPMDEHSCPLIFSS 191
>AF228458-1|AAF63215.1| 449|Homo sapiens GABAA receptor gamma 3
subunit protein.
Length = 449
Score = 47.6 bits (108), Expect = 6e-05
Identities = 35/147 (23%), Positives = 63/147 (42%), Gaps = 7/147 (4%)
Frame = +2
Query: 125 TSLSLMIDSLLATYDRDSPPDSKI---VVNLTLHLRHAN-IRESESTVRIQADLQMNWID 292
T ++L+++ LL YD+ PD I V+++ +++ + +I W D
Sbjct: 27 TDVTLILNKLLREYDKKLRPDIGIKPTVIDVDIYVNSIGPVSSINMEYQIDIFFAQTWTD 86
Query: 293 KRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKR 463
RL +N+ + +W PD + N+ A R+ N+G + + R
Sbjct: 87 SRLRFNSTMKILTLNSNMVGLIWIPDTIFRNSKTAEAHWITTPNQLLRIWNDGKILYTLR 146
Query: 464 LDISTPISMQLDNWPNDMQTCTFKFGS 544
L I+ +QL N+P D +C F S
Sbjct: 147 LTINAECQLQLHNFPMDEHSCPLIFSS 173
>U30461-1|AAB52519.1| 554|Homo sapiens GABAA receptor subunit
alpha4 protein.
Length = 554
Score = 46.0 bits (104), Expect = 2e-04
Identities = 36/143 (25%), Positives = 63/143 (44%), Gaps = 8/143 (5%)
Frame = +2
Query: 140 MIDSLLATYD-RDSP----PDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLS 304
++DSLL YD R P P +++ ++ + + + E + + WIDKRL
Sbjct: 51 ILDSLLDGYDNRLRPGFGGPVTEVKTDIYV-TSFGPVSDVEMEYTMDVFFRQTWIDKRLK 109
Query: 305 WNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRA---RVSNNGSVSWIKRLDIS 475
++ + ++W PD N + + + R+ NG++ + RL IS
Sbjct: 110 YDGPIEILRLNNMMVTKVWTPDTFFRNGKKSVSHNMTAPNKLFRIMRNGTILYTMRLTIS 169
Query: 476 TPISMQLDNWPNDMQTCTFKFGS 544
M+L ++P D C KFGS
Sbjct: 170 AECPMRLVDFPMDGHACPLKFGS 192
>S82612-1|AAB37533.2| 478|Homo sapiens 5-hydroxytryptamine type 3AS
receptor subunit protein.
Length = 478
Score = 46.0 bits (104), Expect = 2e-04
Identities = 25/106 (23%), Positives = 46/106 (43%), Gaps = 1/106 (0%)
Frame = +2
Query: 230 NIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAG 406
N+ E + + W D+ L WN ++ T L + ++ +W PD+++
Sbjct: 72 NVDEKNQVLTTYIWYRQYWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINELVDVGKS 131
Query: 407 DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 544
+ + G V K L + T S+ + N+P D+Q C+ F S
Sbjct: 132 PNIPYVYIRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTS 177
>M59216-1|AAA35862.1| 474|Homo sapiens gamma-aminobutyric acid
receptor beta-1 subunit protein.
Length = 474
Score = 46.0 bits (104), Expect = 2e-04
Identities = 38/159 (23%), Positives = 66/159 (41%), Gaps = 7/159 (4%)
Frame = +2
Query: 89 CAIASAAECENATSLSLMIDSLLATYDRDSPPD---SKIVVNLTLHLRHAN-IRESESTV 256
C S E N + + +D LL YD PD + V + + + + + E
Sbjct: 23 CCAHSTNEPSNMSYVKETVDRLLKGYDIRLRPDFGGPPVDVGMRIDVASIDMVSEVNMDY 82
Query: 257 RIQADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---AR 427
+ Q +W DKRLS++ + +++LW PD LN + ++ R
Sbjct: 83 TLTMYFQQSWKDKRLSYSGIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIR 142
Query: 428 VSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 544
+ +G+V + R+ + M L +P D Q CT + S
Sbjct: 143 LHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIES 181
>BC109211-1|AAI09212.1| 632|Homo sapiens gamma-aminobutyric acid
(GABA) receptor, theta protein.
Length = 632
Score = 46.0 bits (104), Expect = 2e-04
Identities = 35/145 (24%), Positives = 60/145 (41%), Gaps = 7/145 (4%)
Frame = +2
Query: 113 CENATSLSLMIDSLLATYDRDSPPD---SKIVVNLTLHLRHAN-IRESESTVRIQADLQM 280
C N + ++D +L+ YD P+ + + V +++++ I E I
Sbjct: 53 CANEAVVQKILDRVLSRYDVRLRPNFGGAPVPVRISIYVTSIEQISEMNMDYTITMFFHQ 112
Query: 281 NWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSN---NGSVS 451
W D RL++ + E+LW PD LN+ D + RV +G+V
Sbjct: 113 TWKDSRLAYYETTLNLTLDYRMHEKLWVPDCYFLNSKDAFVHDVTVENRVFQLHPDGTVR 172
Query: 452 WIKRLDISTPISMQLDNWPNDMQTC 526
+ RL + S+ L +P D Q C
Sbjct: 173 YGIRLTTTAACSLDLHKFPMDKQAC 197
>BC109210-1|AAI09211.1| 632|Homo sapiens gamma-aminobutyric acid
(GABA) receptor, theta protein.
Length = 632
Score = 46.0 bits (104), Expect = 2e-04
Identities = 35/145 (24%), Positives = 60/145 (41%), Gaps = 7/145 (4%)
Frame = +2
Query: 113 CENATSLSLMIDSLLATYDRDSPPD---SKIVVNLTLHLRHAN-IRESESTVRIQADLQM 280
C N + ++D +L+ YD P+ + + V +++++ I E I
Sbjct: 53 CANEAVVQKILDRVLSRYDVRLRPNFGGAPVPVRISIYVTSIEQISEMNMDYTITMFFHQ 112
Query: 281 NWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSN---NGSVS 451
W D RL++ + E+LW PD LN+ D + RV +G+V
Sbjct: 113 TWKDSRLAYYETTLNLTLDYRMHEKLWVPDCYFLNSKDAFVHDVTVENRVFQLHPDGTVR 172
Query: 452 WIKRLDISTPISMQLDNWPNDMQTC 526
+ RL + S+ L +P D Q C
Sbjct: 173 YGIRLTTTAACSLDLHKFPMDKQAC 197
>BC035055-1|AAH35055.1| 554|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 4 protein.
Length = 554
Score = 46.0 bits (104), Expect = 2e-04
Identities = 36/143 (25%), Positives = 63/143 (44%), Gaps = 8/143 (5%)
Frame = +2
Query: 140 MIDSLLATYD-RDSP----PDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLS 304
++DSLL YD R P P +++ ++ + + + E + + WIDKRL
Sbjct: 51 ILDSLLDGYDNRLRPGFGGPVTEVKTDIYV-TSFGPVSDVEMEYTMDVFFRQTWIDKRLK 109
Query: 305 WNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRA---RVSNNGSVSWIKRLDIS 475
++ + ++W PD N + + + R+ NG++ + RL IS
Sbjct: 110 YDGPIEILRLNNMMVTKVWTPDTFFRNGKKSVSHNMTAPNKLFRIMRNGTILYTMRLTIS 169
Query: 476 TPISMQLDNWPNDMQTCTFKFGS 544
M+L ++P D C KFGS
Sbjct: 170 AECPMRLVDFPMDGHACPLKFGS 192
>AF189259-1|AAF70380.1| 632|Homo sapiens GABA-A receptor theta
subunit protein.
Length = 632
Score = 46.0 bits (104), Expect = 2e-04
Identities = 35/145 (24%), Positives = 60/145 (41%), Gaps = 7/145 (4%)
Frame = +2
Query: 113 CENATSLSLMIDSLLATYDRDSPPD---SKIVVNLTLHLRHAN-IRESESTVRIQADLQM 280
C N + ++D +L+ YD P+ + + V +++++ I E I
Sbjct: 53 CANEAVVQKILDRVLSRYDVRLRPNFGGAPVPVRISIYVTSIEQISEMNMDYTITMFFHQ 112
Query: 281 NWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSN---NGSVS 451
W D RL++ + E+LW PD LN+ D + RV +G+V
Sbjct: 113 TWKDSRLAYYETTLNLTLDYRMHEKLWVPDCYFLNSKDAFVHDVTVENRVFQLHPDGTVR 172
Query: 452 WIKRLDISTPISMQLDNWPNDMQTC 526
+ RL + S+ L +P D Q C
Sbjct: 173 YGIRLTTTAACSLDLHKFPMDKQAC 197
>AF144648-1|AAD51172.1| 627|Homo sapiens GABA-A receptor theta
protein.
Length = 627
Score = 46.0 bits (104), Expect = 2e-04
Identities = 35/145 (24%), Positives = 60/145 (41%), Gaps = 7/145 (4%)
Frame = +2
Query: 113 CENATSLSLMIDSLLATYDRDSPPD---SKIVVNLTLHLRHAN-IRESESTVRIQADLQM 280
C N + ++D +L+ YD P+ + + V +++++ I E I
Sbjct: 48 CANEAVVQKILDRVLSRYDVRLRPNFGGAPVPVRISIYVTSIEQISEMNMDYTITMFFHQ 107
Query: 281 NWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSN---NGSVS 451
W D RL++ + E+LW PD LN+ D + RV +G+V
Sbjct: 108 TWKDSRLAYYETTLNLTLDYRMHEKLWVPDCYFLNSKDAFVHDVTVENRVFQLHPDGTVR 167
Query: 452 WIKRLDISTPISMQLDNWPNDMQTC 526
+ RL + S+ L +P D Q C
Sbjct: 168 YGIRLTTTAACSLDLHKFPMDKQAC 192
>S77554-1|AAB33983.1| 474|Homo sapiens GABAA receptor beta 2
subunit protein.
Length = 474
Score = 45.6 bits (103), Expect = 2e-04
Identities = 39/159 (24%), Positives = 66/159 (41%), Gaps = 7/159 (4%)
Frame = +2
Query: 89 CAIASAAECENATSLSLMIDSLLATYDRDSPPD---SKIVVNLTLHLRHAN-IRESESTV 256
CA S + N + + +D LL YD PD + V + + + + + E
Sbjct: 23 CA-QSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDIASIDMVSEVNMDY 81
Query: 257 RIQADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---AR 427
+ Q W DKRLS+N + +++LW PD LN + ++ R
Sbjct: 82 TLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIR 141
Query: 428 VSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 544
+ +G+V + R+ + M L +P D Q CT + S
Sbjct: 142 LHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIES 180
>S77553-1|AAB33982.1| 512|Homo sapiens GABAA receptor beta 2
subunit protein.
Length = 512
Score = 45.6 bits (103), Expect = 2e-04
Identities = 39/159 (24%), Positives = 66/159 (41%), Gaps = 7/159 (4%)
Frame = +2
Query: 89 CAIASAAECENATSLSLMIDSLLATYDRDSPPD---SKIVVNLTLHLRHAN-IRESESTV 256
CA S + N + + +D LL YD PD + V + + + + + E
Sbjct: 23 CA-QSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDIASIDMVSEVNMDY 81
Query: 257 RIQADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---AR 427
+ Q W DKRLS+N + +++LW PD LN + ++ R
Sbjct: 82 TLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIR 141
Query: 428 VSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 544
+ +G+V + R+ + M L +P D Q CT + S
Sbjct: 142 LHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIES 180
>S67368-1|AAB29370.1| 474|Homo sapiens gamma-aminobutyric acid A
receptor beta 2 subunit protein.
Length = 474
Score = 45.6 bits (103), Expect = 2e-04
Identities = 39/159 (24%), Positives = 66/159 (41%), Gaps = 7/159 (4%)
Frame = +2
Query: 89 CAIASAAECENATSLSLMIDSLLATYDRDSPPD---SKIVVNLTLHLRHAN-IRESESTV 256
CA S + N + + +D LL YD PD + V + + + + + E
Sbjct: 23 CA-QSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDIASIDMVSEVNMDY 81
Query: 257 RIQADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---AR 427
+ Q W DKRLS+N + +++LW PD LN + ++ R
Sbjct: 82 TLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIR 141
Query: 428 VSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 544
+ +G+V + R+ + M L +P D Q CT + S
Sbjct: 142 LHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIES 180
>D49394-1|BAA08387.1| 478|Homo sapiens serotonin 5-HT3 receptor
protein.
Length = 478
Score = 45.6 bits (103), Expect = 2e-04
Identities = 25/106 (23%), Positives = 46/106 (43%), Gaps = 1/106 (0%)
Frame = +2
Query: 230 NIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAG 406
N+ E + + W D+ L WN ++ T L + ++ +W PD+++
Sbjct: 72 NVDEKNQVLTTYIWYRQYWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKS 131
Query: 407 DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 544
+ + G V K L + T S+ + N+P D+Q C+ F S
Sbjct: 132 PNIPYVYIRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTS 177
>BT007204-1|AAP35868.1| 484|Homo sapiens 5-hydroxytryptamine
(serotonin) receptor 3A protein.
Length = 484
Score = 45.6 bits (103), Expect = 2e-04
Identities = 25/106 (23%), Positives = 46/106 (43%), Gaps = 1/106 (0%)
Frame = +2
Query: 230 NIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAG 406
N+ E + + W D+ L WN ++ T L + ++ +W PD+++
Sbjct: 78 NVDEKNQVLTTYIWYRQYWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKS 137
Query: 407 DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 544
+ + G V K L + T S+ + N+P D+Q C+ F S
Sbjct: 138 PNIPYVYIRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTS 183
>BC105639-1|AAI05640.1| 474|Homo sapiens GABRB2 protein protein.
Length = 474
Score = 45.6 bits (103), Expect = 2e-04
Identities = 39/159 (24%), Positives = 66/159 (41%), Gaps = 7/159 (4%)
Frame = +2
Query: 89 CAIASAAECENATSLSLMIDSLLATYDRDSPPD---SKIVVNLTLHLRHAN-IRESESTV 256
CA S + N + + +D LL YD PD + V + + + + + E
Sbjct: 23 CA-QSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDIASIDMVSEVNMDY 81
Query: 257 RIQADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---AR 427
+ Q W DKRLS+N + +++LW PD LN + ++ R
Sbjct: 82 TLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIR 141
Query: 428 VSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 544
+ +G+V + R+ + M L +P D Q CT + S
Sbjct: 142 LHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIES 180
>BC099719-1|AAH99719.1| 474|Homo sapiens GABRB2 protein protein.
Length = 474
Score = 45.6 bits (103), Expect = 2e-04
Identities = 39/159 (24%), Positives = 66/159 (41%), Gaps = 7/159 (4%)
Frame = +2
Query: 89 CAIASAAECENATSLSLMIDSLLATYDRDSPPD---SKIVVNLTLHLRHAN-IRESESTV 256
CA S + N + + +D LL YD PD + V + + + + + E
Sbjct: 23 CA-QSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDIASIDMVSEVNMDY 81
Query: 257 RIQADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---AR 427
+ Q W DKRLS+N + +++LW PD LN + ++ R
Sbjct: 82 TLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIR 141
Query: 428 VSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 544
+ +G+V + R+ + M L +P D Q CT + S
Sbjct: 142 LHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIES 180
>BC099705-1|AAH99705.1| 474|Homo sapiens GABRB2 protein protein.
Length = 474
Score = 45.6 bits (103), Expect = 2e-04
Identities = 39/159 (24%), Positives = 66/159 (41%), Gaps = 7/159 (4%)
Frame = +2
Query: 89 CAIASAAECENATSLSLMIDSLLATYDRDSPPD---SKIVVNLTLHLRHAN-IRESESTV 256
CA S + N + + +D LL YD PD + V + + + + + E
Sbjct: 23 CA-QSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDIASIDMVSEVNMDY 81
Query: 257 RIQADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---AR 427
+ Q W DKRLS+N + +++LW PD LN + ++ R
Sbjct: 82 TLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIR 141
Query: 428 VSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 544
+ +G+V + R+ + M L +P D Q CT + S
Sbjct: 142 LHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIES 180
>BC004453-1|AAH04453.2| 478|Homo sapiens 5-hydroxytryptamine
(serotonin) receptor 3A protein.
Length = 478
Score = 45.6 bits (103), Expect = 2e-04
Identities = 25/106 (23%), Positives = 46/106 (43%), Gaps = 1/106 (0%)
Frame = +2
Query: 230 NIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAG 406
N+ E + + W D+ L WN ++ T L + ++ +W PD+++
Sbjct: 72 NVDEKNQVLTTYIWYRQYWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKS 131
Query: 407 DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 544
+ + G V K L + T S+ + N+P D+Q C+ F S
Sbjct: 132 PNIPYVYIRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTS 177
>BC002354-1|AAH02354.1| 478|Homo sapiens 5-hydroxytryptamine
(serotonin) receptor 3A protein.
Length = 478
Score = 45.6 bits (103), Expect = 2e-04
Identities = 25/106 (23%), Positives = 46/106 (43%), Gaps = 1/106 (0%)
Frame = +2
Query: 230 NIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAG 406
N+ E + + W D+ L WN ++ T L + ++ +W PD+++
Sbjct: 72 NVDEKNQVLTTYIWYRQYWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKS 131
Query: 407 DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 544
+ + G V K L + T S+ + N+P D+Q C+ F S
Sbjct: 132 PNIPYVYIRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTS 177
>AJ005205-1|CAA06442.3| 478|Homo sapiens serotonin 3 receptor
protein.
Length = 478
Score = 45.6 bits (103), Expect = 2e-04
Identities = 25/106 (23%), Positives = 46/106 (43%), Gaps = 1/106 (0%)
Frame = +2
Query: 230 NIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAG 406
N+ E + + W D+ L WN ++ T L + ++ +W PD+++
Sbjct: 72 NVDEKNQVLTTYIWYRQYWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKS 131
Query: 407 DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 544
+ + G V K L + T S+ + N+P D+Q C+ F S
Sbjct: 132 PNIPYVYIRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTS 177
>AJ003080-1|CAA05853.1| 238|Homo sapiens serotonin receptor
protein.
Length = 238
Score = 45.6 bits (103), Expect = 2e-04
Identities = 25/106 (23%), Positives = 46/106 (43%), Gaps = 1/106 (0%)
Frame = +2
Query: 230 NIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAG 406
N+ E + + W D+ L WN ++ T L + ++ +W PD+++
Sbjct: 72 NVDEKNQVLTTYIWYRQYWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKS 131
Query: 407 DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 544
+ + G V K L + T S+ + N+P D+Q C+ F S
Sbjct: 132 PNIPYVYIRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTS 177
>AJ003079-1|CAA05852.1| 478|Homo sapiens 5-hydroxytryptamine3
receptor protein.
Length = 478
Score = 45.6 bits (103), Expect = 2e-04
Identities = 25/106 (23%), Positives = 46/106 (43%), Gaps = 1/106 (0%)
Frame = +2
Query: 230 NIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAG 406
N+ E + + W D+ L WN ++ T L + ++ +W PD+++
Sbjct: 72 NVDEKNQVLTTYIWYRQYWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKS 131
Query: 407 DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 544
+ + G V K L + T S+ + N+P D+Q C+ F S
Sbjct: 132 PNIPYVYIRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTS 177
>AJ003078-1|CAA05851.1| 510|Homo sapiens serotonin receptor
protein.
Length = 510
Score = 45.6 bits (103), Expect = 2e-04
Identities = 25/106 (23%), Positives = 46/106 (43%), Gaps = 1/106 (0%)
Frame = +2
Query: 230 NIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAG 406
N+ E + + W D+ L WN ++ T L + ++ +W PD+++
Sbjct: 72 NVDEKNQVLTTYIWYRQYWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKS 131
Query: 407 DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 544
+ + G V K L + T S+ + N+P D+Q C+ F S
Sbjct: 132 PNIPYVYIRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTS 177
>AF498984-1|AAM21131.1| 478|Homo sapiens 5-hydroxytryptamine
receptor 3A protein.
Length = 478
Score = 45.6 bits (103), Expect = 2e-04
Identities = 25/106 (23%), Positives = 46/106 (43%), Gaps = 1/106 (0%)
Frame = +2
Query: 230 NIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAG 406
N+ E + + W D+ L WN ++ T L + ++ +W PD+++
Sbjct: 72 NVDEKNQVLTTYIWYRQYWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKS 131
Query: 407 DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 544
+ + G V K L + T S+ + N+P D+Q C+ F S
Sbjct: 132 PNIPYVYIRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTS 177
>X14767-1|CAA32875.1| 474|Homo sapiens GABA-A receptor beta 1
subunit protein.
Length = 474
Score = 45.2 bits (102), Expect = 3e-04
Identities = 38/159 (23%), Positives = 65/159 (40%), Gaps = 7/159 (4%)
Frame = +2
Query: 89 CAIASAAECENATSLSLMIDSLLATYDRDSPPD---SKIVVNLTLHLRHAN-IRESESTV 256
C S E N + +D LL YD PD + V + + + + + E
Sbjct: 23 CCAHSTNEPSNMPYVKETVDRLLKGYDIRLRPDFGGPPVDVGMRIDVASIDMVSEVNMDY 82
Query: 257 RIQADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---AR 427
+ Q +W DKRLS++ + +++LW PD LN + ++ R
Sbjct: 83 TLTMYFQQSWKDKRLSYSGIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIR 142
Query: 428 VSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 544
+ +G+V + R+ + M L +P D Q CT + S
Sbjct: 143 LHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIES 181
>X52009-1|CAA36258.1| 449|Homo sapiens inhibitory glycine receptor
protein.
Length = 449
Score = 44.8 bits (101), Expect = 4e-04
Identities = 29/109 (26%), Positives = 49/109 (44%), Gaps = 4/109 (3%)
Frame = +2
Query: 230 NIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERLWRPDVVLLNAAATTAG 406
+I E+ R+ L+ W D RL++N S + +W+PD+ N
Sbjct: 78 SIAETTMDYRVNIFLRQQWNDPRLAYNEYPDDSLDLDPSMLDSIWKPDLFFANEKGAHFH 137
Query: 407 DYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 544
+ R+S NG+V + R+ ++ M L N+P D+QTC + S
Sbjct: 138 EITTDNKLLRISRNGNVLYSIRITLTLACPMDLKNFPMDVQTCIMQLES 186
>BC114947-1|AAI14948.1| 457|Homo sapiens GLRA1 protein protein.
Length = 457
Score = 44.8 bits (101), Expect = 4e-04
Identities = 29/109 (26%), Positives = 49/109 (44%), Gaps = 4/109 (3%)
Frame = +2
Query: 230 NIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERLWRPDVVLLNAAATTAG 406
+I E+ R+ L+ W D RL++N S + +W+PD+ N
Sbjct: 78 SIAETTMDYRVNIFLRQQWNDPRLAYNEYPDDSLDLDPSMLDSIWKPDLFFANEKGAHFH 137
Query: 407 DYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 544
+ R+S NG+V + R+ ++ M L N+P D+QTC + S
Sbjct: 138 EITTDNKLLRISRNGNVLYSIRITLTLACPMDLKNFPMDVQTCIMQLES 186
>BC074980-1|AAH74980.1| 449|Homo sapiens glycine receptor, alpha 1
(startle disease/hyperekplexia) protein.
Length = 449
Score = 44.8 bits (101), Expect = 4e-04
Identities = 29/109 (26%), Positives = 49/109 (44%), Gaps = 4/109 (3%)
Frame = +2
Query: 230 NIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERLWRPDVVLLNAAATTAG 406
+I E+ R+ L+ W D RL++N S + +W+PD+ N
Sbjct: 78 SIAETTMDYRVNIFLRQQWNDPRLAYNEYPDDSLDLDPSMLDSIWKPDLFFANEKGAHFH 137
Query: 407 DYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 544
+ R+S NG+V + R+ ++ M L N+P D+QTC + S
Sbjct: 138 EITTDNKLLRISRNGNVLYSIRITLTLACPMDLKNFPMDVQTCIMQLES 186
>BC033801-1|AAH33801.1| 452|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, delta protein.
Length = 452
Score = 44.4 bits (100), Expect = 5e-04
Identities = 36/135 (26%), Positives = 58/135 (42%), Gaps = 7/135 (5%)
Frame = +2
Query: 143 IDSLLATYDRDSPPD-SKIVVNLTLHLRHANI---RESESTVRIQADLQMNWIDKRLSWN 310
+D L+A Y R+ P VN+ L L A+I E+ + L +W D RLS+N
Sbjct: 44 LDGLIAGYARNFRPGIGGPPVNVALALEVASIDHISEANMEYTMTVFLHQSWRDSRLSYN 103
Query: 311 AGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTP 481
++LW PD ++NA + D + R+ +G + + R+ +
Sbjct: 104 HTNETLGLDSRFVDKLWLPDTFIVNAKSAWFHDVTVENKLIRLQPDGVILYSIRITSTVA 163
Query: 482 ISMQLDNWPNDMQTC 526
M L +P D Q C
Sbjct: 164 CDMDLAKYPMDEQEC 178
>AL391845-4|CAI15436.1| 452|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, delta protein.
Length = 452
Score = 44.4 bits (100), Expect = 5e-04
Identities = 36/135 (26%), Positives = 58/135 (42%), Gaps = 7/135 (5%)
Frame = +2
Query: 143 IDSLLATYDRDSPPD-SKIVVNLTLHLRHANI---RESESTVRIQADLQMNWIDKRLSWN 310
+D L+A Y R+ P VN+ L L A+I E+ + L +W D RLS+N
Sbjct: 44 LDGLIAGYARNFRPGIGGPPVNVALALEVASIDHISEANMEYTMTVFLHQSWRDSRLSYN 103
Query: 311 AGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTP 481
++LW PD ++NA + D + R+ +G + + R+ +
Sbjct: 104 HTNETLGLDSRFVDKLWLPDTFIVNAKSAWFHDVTVENKLIRLQPDGVILYSIRITSTVA 163
Query: 482 ISMQLDNWPNDMQTC 526
M L +P D Q C
Sbjct: 164 CDMDLAKYPMDEQEC 178
>AF016917-1|AAB70007.1| 452|Homo sapiens GABA-A receptor delta
subunit protein.
Length = 452
Score = 44.4 bits (100), Expect = 5e-04
Identities = 36/135 (26%), Positives = 58/135 (42%), Gaps = 7/135 (5%)
Frame = +2
Query: 143 IDSLLATYDRDSPPD-SKIVVNLTLHLRHANI---RESESTVRIQADLQMNWIDKRLSWN 310
+D L+A Y R+ P VN+ L L A+I E+ + L +W D RLS+N
Sbjct: 44 LDGLIAGYARNFRPGIGGPPVNVALALEVASIDHISEANMEYTMTVFLHQSWRDSRLSYN 103
Query: 311 AGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTP 481
++LW PD ++NA + D + R+ +G + + R+ +
Sbjct: 104 HTNETLGLDSRFVDKLWLPDTFIVNAKSAWFHDVTVENKLIRLQPDGVILYSIRITSTVA 163
Query: 482 ISMQLDNWPNDMQTC 526
M L +P D Q C
Sbjct: 164 CDMDLAKYPMDEQEC 178
>Z93848-1|CAI41994.1| 376|Homo sapiens glycine receptor, alpha 4
protein.
Length = 376
Score = 43.6 bits (98), Expect = 0.001
Identities = 31/125 (24%), Positives = 54/125 (43%), Gaps = 4/125 (3%)
Frame = +2
Query: 182 PDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERL 358
P + N+ ++ ++I ++ R+ L+ W D RLS+ S + +
Sbjct: 28 PPVNVTCNIFIN-SFSSITKTTMDYRVNVFLRQQWNDPRLSYREYPDDSLDLDPSMLDSI 86
Query: 359 WRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCT 529
W+PD+ N + R+ NG+V + RL + M L N+P D+QTCT
Sbjct: 87 WKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLILSCLMDLKNFPMDIQTCT 146
Query: 530 FKFGS 544
+ S
Sbjct: 147 MQLES 151
>AL049610-1|CAI42158.1| 376|Homo sapiens glycine receptor, alpha 4
protein.
Length = 376
Score = 43.6 bits (98), Expect = 0.001
Identities = 31/125 (24%), Positives = 54/125 (43%), Gaps = 4/125 (3%)
Frame = +2
Query: 182 PDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERL 358
P + N+ ++ ++I ++ R+ L+ W D RLS+ S + +
Sbjct: 28 PPVNVTCNIFIN-SFSSITKTTMDYRVNVFLRQQWNDPRLSYREYPDDSLDLDPSMLDSI 86
Query: 359 WRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCT 529
W+PD+ N + R+ NG+V + RL + M L N+P D+QTCT
Sbjct: 87 WKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLILSCLMDLKNFPMDIQTCT 146
Query: 530 FKFGS 544
+ S
Sbjct: 147 MQLES 151
>U95367-1|AAC51357.1| 440|Homo sapiens GABA-A receptor pi subunit
protein.
Length = 440
Score = 43.2 bits (97), Expect = 0.001
Identities = 39/154 (25%), Positives = 71/154 (46%), Gaps = 9/154 (5%)
Frame = +2
Query: 110 ECENATSLSLM-IDSLLATYDRDSPPD---SKIVVNLTLHLRH-ANIRESESTVRIQADL 274
E + LSL ++L A Y++ P+ + + LTL + ++I ES L
Sbjct: 29 EVGRSDKLSLPGFENLTAGYNKFLRPNFGGEPVQIALTLDIASISSISESNMDYTATIYL 88
Query: 275 QMNWIDKRLSWNAGE-WGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNG 442
+ W+D+RL + + + LV E LW PD ++ + + + + R+ +NG
Sbjct: 89 RQRWMDQRLVFEGNKSFTLDARLV--EFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNG 146
Query: 443 SVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 544
+V + R+ + +M L +P D QTC + S
Sbjct: 147 TVLYALRITTTVACNMDLSKYPMDTQTCKLQLES 180
>BC109106-1|AAI09107.1| 440|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, pi protein.
Length = 440
Score = 43.2 bits (97), Expect = 0.001
Identities = 39/154 (25%), Positives = 71/154 (46%), Gaps = 9/154 (5%)
Frame = +2
Query: 110 ECENATSLSLM-IDSLLATYDRDSPPD---SKIVVNLTLHLRH-ANIRESESTVRIQADL 274
E + LSL ++L A Y++ P+ + + LTL + ++I ES L
Sbjct: 29 EVGRSDKLSLPGFENLTAGYNKFLRPNFGGEPVQIALTLDIASISSISESNMDYTATIYL 88
Query: 275 QMNWIDKRLSWNAGE-WGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNG 442
+ W+D+RL + + + LV E LW PD ++ + + + + R+ +NG
Sbjct: 89 RQRWMDQRLVFEGNKSFTLDARLV--EFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNG 146
Query: 443 SVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 544
+V + R+ + +M L +P D QTC + S
Sbjct: 147 TVLYALRITTTVACNMDLSKYPMDTQTCKLQLES 180
>BC109105-1|AAI09106.1| 440|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, pi protein.
Length = 440
Score = 43.2 bits (97), Expect = 0.001
Identities = 39/154 (25%), Positives = 71/154 (46%), Gaps = 9/154 (5%)
Frame = +2
Query: 110 ECENATSLSLM-IDSLLATYDRDSPPD---SKIVVNLTLHLRH-ANIRESESTVRIQADL 274
E + LSL ++L A Y++ P+ + + LTL + ++I ES L
Sbjct: 29 EVGRSDKLSLPGFENLTAGYNKFLRPNFGGEPVQIALTLDIASISSISESNMDYTATIYL 88
Query: 275 QMNWIDKRLSWNAGE-WGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNG 442
+ W+D+RL + + + LV E LW PD ++ + + + + R+ +NG
Sbjct: 89 RQRWMDQRLVFEGNKSFTLDARLV--EFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNG 146
Query: 443 SVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 544
+V + R+ + +M L +P D QTC + S
Sbjct: 147 TVLYALRITTTVACNMDLSKYPMDTQTCKLQLES 180
>BC074865-1|AAH74865.1| 440|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, pi protein.
Length = 440
Score = 43.2 bits (97), Expect = 0.001
Identities = 39/154 (25%), Positives = 71/154 (46%), Gaps = 9/154 (5%)
Frame = +2
Query: 110 ECENATSLSLM-IDSLLATYDRDSPPD---SKIVVNLTLHLRH-ANIRESESTVRIQADL 274
E + LSL ++L A Y++ P+ + + LTL + ++I ES L
Sbjct: 29 EVGRSDKLSLPGFENLTAGYNKFLRPNFGGEPVQIALTLDIASISSISESNMDYTATIYL 88
Query: 275 QMNWIDKRLSWNAGE-WGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNG 442
+ W+D+RL + + + LV E LW PD ++ + + + + R+ +NG
Sbjct: 89 RQRWMDQRLVFEGNKSFTLDARLV--EFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNG 146
Query: 443 SVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 544
+V + R+ + +M L +P D QTC + S
Sbjct: 147 TVLYALRITTTVACNMDLSKYPMDTQTCKLQLES 180
>BC074810-1|AAH74810.1| 440|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, pi protein.
Length = 440
Score = 43.2 bits (97), Expect = 0.001
Identities = 39/154 (25%), Positives = 71/154 (46%), Gaps = 9/154 (5%)
Frame = +2
Query: 110 ECENATSLSLM-IDSLLATYDRDSPPD---SKIVVNLTLHLRH-ANIRESESTVRIQADL 274
E + LSL ++L A Y++ P+ + + LTL + ++I ES L
Sbjct: 29 EVGRSDKLSLPGFENLTAGYNKFLRPNFGGEPVQIALTLDIASISSISESNMDYTATIYL 88
Query: 275 QMNWIDKRLSWNAGE-WGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNG 442
+ W+D+RL + + + LV E LW PD ++ + + + + R+ +NG
Sbjct: 89 RQRWMDQRLVFEGNKSFTLDARLV--EFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNG 146
Query: 443 SVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 544
+V + R+ + +M L +P D QTC + S
Sbjct: 147 TVLYALRITTTVACNMDLSKYPMDTQTCKLQLES 180
>AF009702-1|AAC24194.1| 440|Homo sapiens GABA-A receptor pi subunit
protein.
Length = 440
Score = 43.2 bits (97), Expect = 0.001
Identities = 39/154 (25%), Positives = 71/154 (46%), Gaps = 9/154 (5%)
Frame = +2
Query: 110 ECENATSLSLM-IDSLLATYDRDSPPD---SKIVVNLTLHLRH-ANIRESESTVRIQADL 274
E + LSL ++L A Y++ P+ + + LTL + ++I ES L
Sbjct: 29 EVGRSDKLSLPGFENLTAGYNKFLRPNFGGEPVQIALTLDIASISSISESNMDYTATIYL 88
Query: 275 QMNWIDKRLSWNAGE-WGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNG 442
+ W+D+RL + + + LV E LW PD ++ + + + + R+ +NG
Sbjct: 89 RQRWMDQRLVFEGNKSFTLDARLV--EFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNG 146
Query: 443 SVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 544
+V + R+ + +M L +P D QTC + S
Sbjct: 147 TVLYALRITTTVACNMDLSKYPMDTQTCKLQLES 180
>U93917-1|AAC39917.1| 449|Homo sapiens glycine receptor alpha 3
subunit protein.
Length = 449
Score = 42.7 bits (96), Expect = 0.002
Identities = 30/125 (24%), Positives = 54/125 (43%), Gaps = 4/125 (3%)
Frame = +2
Query: 182 PDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERL 358
P + N+ ++ +I E+ R+ L+ W D RL+++ S + +
Sbjct: 68 PPVNVTCNIFIN-SFGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPDDSLDLDPSMLDSI 126
Query: 359 WRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCT 529
W+PD+ N + R+ NG+V + RL ++ M L N+P D+QTC
Sbjct: 127 WKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFPMDVQTCI 186
Query: 530 FKFGS 544
+ S
Sbjct: 187 MQLES 191
>BC074795-1|AAH74795.1| 467|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, gamma 2 protein.
Length = 467
Score = 42.7 bits (96), Expect = 0.002
Identities = 33/145 (22%), Positives = 61/145 (42%), Gaps = 7/145 (4%)
Frame = +2
Query: 131 LSLMIDSLLATYDRDSPPDSKIVVNLTLHLRHANIRESESTVRIQADLQM----NWIDKR 298
+++++++LL YD PD + L + N + + ++ + + W D+R
Sbjct: 66 VTVILNNLLEGYDNKLRPDIGVKPTLIHTDMYVNSIGPVNAINMEYTIDIFFAQTWYDRR 125
Query: 299 LSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYAL---RARVSNNGSVSWIKRLD 469
L +N+ ++W PD N+ A R+ N+G V + RL
Sbjct: 126 LKFNSTIKVLRLNSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYTLRLT 185
Query: 470 ISTPISMQLDNWPNDMQTCTFKFGS 544
I +QL N+P D +C +F S
Sbjct: 186 IDAECQLQLHNFPMDEHSCPLEFSS 210
>BC069348-1|AAH69348.1| 467|Homo sapiens gamma-aminobutyric acid A
receptor, gamma 2, isoform 2 precursor protein.
Length = 467
Score = 42.7 bits (96), Expect = 0.002
Identities = 33/145 (22%), Positives = 61/145 (42%), Gaps = 7/145 (4%)
Frame = +2
Query: 131 LSLMIDSLLATYDRDSPPDSKIVVNLTLHLRHANIRESESTVRIQADLQM----NWIDKR 298
+++++++LL YD PD + L + N + + ++ + + W D+R
Sbjct: 66 VTVILNNLLEGYDNKLRPDIGVKPTLIHTDMYVNSIGPVNAINMEYTIDIFFAQTWYDRR 125
Query: 299 LSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYAL---RARVSNNGSVSWIKRLD 469
L +N+ ++W PD N+ A R+ N+G V + RL
Sbjct: 126 LKFNSTIKVLRLNSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYTLRLT 185
Query: 470 ISTPISMQLDNWPNDMQTCTFKFGS 544
I +QL N+P D +C +F S
Sbjct: 186 IDAECQLQLHNFPMDEHSCPLEFSS 210
>BC059389-1|AAH59389.1| 475|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, gamma 2 protein.
Length = 475
Score = 42.7 bits (96), Expect = 0.002
Identities = 33/145 (22%), Positives = 61/145 (42%), Gaps = 7/145 (4%)
Frame = +2
Query: 131 LSLMIDSLLATYDRDSPPDSKIVVNLTLHLRHANIRESESTVRIQADLQM----NWIDKR 298
+++++++LL YD PD + L + N + + ++ + + W D+R
Sbjct: 66 VTVILNNLLEGYDNKLRPDIGVKPTLIHTDMYVNSIGPVNAINMEYTIDIFFAQTWYDRR 125
Query: 299 LSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYAL---RARVSNNGSVSWIKRLD 469
L +N+ ++W PD N+ A R+ N+G V + RL
Sbjct: 126 LKFNSTIKVLRLNSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYTLRLT 185
Query: 470 ISTPISMQLDNWPNDMQTCTFKFGS 544
I +QL N+P D +C +F S
Sbjct: 186 IDAECQLQLHNFPMDEHSCPLEFSS 210
>BC036086-1|AAH36086.1| 464|Homo sapiens glycine receptor, alpha 3
protein.
Length = 464
Score = 42.7 bits (96), Expect = 0.002
Identities = 30/125 (24%), Positives = 54/125 (43%), Gaps = 4/125 (3%)
Frame = +2
Query: 182 PDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERL 358
P + N+ ++ +I E+ R+ L+ W D RL+++ S + +
Sbjct: 68 PPVNVTCNIFIN-SFGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPDDSLDLDPSMLDSI 126
Query: 359 WRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCT 529
W+PD+ N + R+ NG+V + RL ++ M L N+P D+QTC
Sbjct: 127 WKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFPMDVQTCI 186
Query: 530 FKFGS 544
+ S
Sbjct: 187 MQLES 191
>AF165124-1|AAD50273.1| 467|Homo sapiens gamma-aminobutyric acid A
receptor gamma 2 protein.
Length = 467
Score = 42.7 bits (96), Expect = 0.002
Identities = 33/145 (22%), Positives = 61/145 (42%), Gaps = 7/145 (4%)
Frame = +2
Query: 131 LSLMIDSLLATYDRDSPPDSKIVVNLTLHLRHANIRESESTVRIQADLQM----NWIDKR 298
+++++++LL YD PD + L + N + + ++ + + W D+R
Sbjct: 66 VTVILNNLLEGYDNKLRPDIGVKPTLIHTDMYVNSIGPVNAINMEYTIDIFFAQTWYDRR 125
Query: 299 LSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYAL---RARVSNNGSVSWIKRLD 469
L +N+ ++W PD N+ A R+ N+G V + RL
Sbjct: 126 LKFNSTIKVLRLNSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYTLRLT 185
Query: 470 ISTPISMQLDNWPNDMQTCTFKFGS 544
I +QL N+P D +C +F S
Sbjct: 186 IDAECQLQLHNFPMDEHSCPLEFSS 210
>AF017724-1|AAC39919.1| 465|Homo sapiens glycine receptor alpha 3
subunit protein.
Length = 465
Score = 42.7 bits (96), Expect = 0.002
Identities = 30/125 (24%), Positives = 54/125 (43%), Gaps = 4/125 (3%)
Frame = +2
Query: 182 PDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERL 358
P + N+ ++ +I E+ R+ L+ W D RL+++ S + +
Sbjct: 68 PPVNVTCNIFIN-SFGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPDDSLDLDPSMLDSI 126
Query: 359 WRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCT 529
W+PD+ N + R+ NG+V + RL ++ M L N+P D+QTC
Sbjct: 127 WKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFPMDVQTCI 186
Query: 530 FKFGS 544
+ S
Sbjct: 187 MQLES 191
>BC114967-1|AAI14968.1| 366|Homo sapiens GLRA1 protein protein.
Length = 366
Score = 42.3 bits (95), Expect = 0.002
Identities = 27/100 (27%), Positives = 45/100 (45%), Gaps = 4/100 (4%)
Frame = +2
Query: 257 RIQADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERLWRPDVVLLNAAATTAGDYALR---A 424
R+ L+ W D RL++N S + +W+PD+ N +
Sbjct: 4 RVNIFLRQQWNDPRLAYNEYPDDSLDLDPSMLDSIWKPDLFFANEKGAHFHEITTDNKLL 63
Query: 425 RVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 544
R+S NG+V + R+ ++ M L N+P D+QTC + S
Sbjct: 64 RISRNGNVLYSIRITLTLACPMDLKNFPMDVQTCIMQLES 103
>X15376-1|CAA33437.1| 467|Homo sapiens GABA-A receptor gamma 2
subunit protein.
Length = 467
Score = 41.5 bits (93), Expect = 0.004
Identities = 33/145 (22%), Positives = 61/145 (42%), Gaps = 7/145 (4%)
Frame = +2
Query: 131 LSLMIDSLLATYDRDSPPDSKIVVNLTLHLRHANIRESESTVRIQADLQM----NWIDKR 298
+++++++LL YD PD + L + N + + ++ + + W D+R
Sbjct: 66 VTVILNNLLEGYDNKLRPDIGVKPTLIHTDMYVNSIGPVNAINMEYTIDIFFAQMWYDRR 125
Query: 299 LSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYAL---RARVSNNGSVSWIKRLD 469
L +N+ ++W PD N+ A R+ N+G V + RL
Sbjct: 126 LKFNSTIKVLRLNSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYSLRLT 185
Query: 470 ISTPISMQLDNWPNDMQTCTFKFGS 544
I +QL N+P D +C +F S
Sbjct: 186 IDAECQLQLHNFPMDEHSCPLEFSS 210
>BC031087-1|AAH31087.1| 465|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, gamma 1 protein.
Length = 465
Score = 41.5 bits (93), Expect = 0.004
Identities = 34/145 (23%), Positives = 59/145 (40%), Gaps = 7/145 (4%)
Frame = +2
Query: 131 LSLMIDSLLATYDRDSPPDSKI---VVNLTLHLRHAN-IRESESTVRIQADLQMNWIDKR 298
++ +++SLL YD PD + V+ +++ + I W D R
Sbjct: 64 ITQILNSLLQGYDNKLRPDIGVRPTVIETDVYVNSIGPVDPINMEYTIDIIFAQTWFDSR 123
Query: 299 LSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLD 469
L +N+ ++W PD N+ + A R+ N+G V + RL
Sbjct: 124 LKFNSTMKVLMLNSNMVGKIWIPDTFFRNSRKSDAHWITTPNRLLRIWNDGRVLYTLRLT 183
Query: 470 ISTPISMQLDNWPNDMQTCTFKFGS 544
I+ +QL N+P D +C +F S
Sbjct: 184 INAECYLQLHNFPMDEHSCPLEFSS 208
>BC022449-1|AAH22449.1| 474|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, beta 1 protein.
Length = 474
Score = 40.7 bits (91), Expect = 0.007
Identities = 37/159 (23%), Positives = 65/159 (40%), Gaps = 7/159 (4%)
Frame = +2
Query: 89 CAIASAAECENATSLSLMIDSLLATYDRDSPPD---SKIVVNLTLHLRHAN-IRESESTV 256
C S E N + + +D LL YD PD + V + + + + + E
Sbjct: 23 CCAHSTNEPSNMSYVKETVDRLLKGYDIRLRPDFGGPPVDVGMRIDVASIDMVSEVNMDY 82
Query: 257 RIQADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---AR 427
+ Q +W DKRLS++ + +++L PD LN + ++ R
Sbjct: 83 TLTMYFQQSWKDKRLSYSGIPLNLTLDNRVADQLCVPDTYFLNDKKSFVHGVTVKNRMIR 142
Query: 428 VSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 544
+ +G+V + R+ + M L +P D Q CT + S
Sbjct: 143 LHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIES 181
>AB046822-1|BAB13428.1| 1003|Homo sapiens KIAA1602 protein protein.
Length = 1003
Score = 34.7 bits (76), Expect = 0.44
Identities = 24/72 (33%), Positives = 28/72 (38%), Gaps = 1/72 (1%)
Frame = -2
Query: 825 GXGXSXGRRQGXPXGGRXXGXPXXNTGAGXPGAXXRG-RVPGKXXGTLPXELPPRHGPGX 649
G G S Q P + G P G G P A G + G LP L G G
Sbjct: 70 GPGQSSSPDQAPPQLSKSKGLPKSAWGGGTPEAHRPGFGATSEGQGPLPF-LSMFMGAGD 128
Query: 648 APHWTEPSHPHA 613
AP + P HPH+
Sbjct: 129 APLGSRPGHPHS 140
>AB209359-1|BAD92596.1| 533|Homo sapiens cholinergic receptor,
nicotinic, alpha polypeptide 4 precursor variant
protein.
Length = 533
Score = 34.3 bits (75), Expect = 0.58
Identities = 18/63 (28%), Positives = 28/63 (44%)
Frame = +2
Query: 356 LWRPDVVLLNAAATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFK 535
LW +A A + +A + ++G V W + S+ + +P D Q CT K
Sbjct: 25 LWLCCCTFTSADGDFAVTHLTKAHLFHDGRVQWTPPAIYKSSCSIDVTFFPFDQQNCTMK 84
Query: 536 FGS 544
FGS
Sbjct: 85 FGS 87
>BC096291-1|AAH96291.1| 556|Homo sapiens CHRNA4 protein protein.
Length = 556
Score = 33.5 bits (73), Expect = 1.0
Identities = 17/51 (33%), Positives = 27/51 (52%), Gaps = 4/51 (7%)
Frame = +2
Query: 404 GDYAL----RARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 544
GD+A+ +A + ++G V W + S+ + +P D Q CT KFGS
Sbjct: 60 GDFAVTHLTKAHLFHDGRVQWTPPAIYKSSCSIDVTFFPFDQQNCTMKFGS 110
>BC044636-1|AAH44636.1| 520|Homo sapiens YLPM1 protein protein.
Length = 520
Score = 33.1 bits (72), Expect = 1.4
Identities = 17/46 (36%), Positives = 19/46 (41%)
Frame = +2
Query: 689 VPXXFPGTRPRXXAPGXPAPVFXXGXPXXLPPXGXPCRLPXXXPXP 826
+P P T P PG P PV P +PP G P L P P
Sbjct: 375 MPPALPATVP---PPGMPPPVMPPSLPTSVPPPGMPPSLSSAGPPP 417
>AK091050-1|BAC03574.1| 723|Homo sapiens protein ( Homo sapiens
cDNA FLJ33731 fis, clone BRAWH2017685, moderately
similar to Mus musculus mRNA for nuclear protein ZAP. ).
Length = 723
Score = 33.1 bits (72), Expect = 1.4
Identities = 17/46 (36%), Positives = 19/46 (41%)
Frame = +2
Query: 689 VPXXFPGTRPRXXAPGXPAPVFXXGXPXXLPPXGXPCRLPXXXPXP 826
+P P T P PG P PV P +PP G P L P P
Sbjct: 116 MPPALPATVP---PPGMPPPVMPPSLPTSVPPPGMPPSLSSAGPPP 158
>AK090435-1|BAC03416.1| 1766|Homo sapiens FLJ00353 protein protein.
Length = 1766
Score = 33.1 bits (72), Expect = 1.4
Identities = 17/46 (36%), Positives = 19/46 (41%)
Frame = +2
Query: 689 VPXXFPGTRPRXXAPGXPAPVFXXGXPXXLPPXGXPCRLPXXXPXP 826
+P P T P PG P PV P +PP G P L P P
Sbjct: 173 MPPALPATVP---PPGMPPPVMPPSLPTSVPPPGMPPSLSSAGPPP 215
>U83981-1|AAC25631.1| 674|Homo sapiens apoptosis associated protein
protein.
Length = 674
Score = 31.1 bits (67), Expect = 5.5
Identities = 17/46 (36%), Positives = 22/46 (47%), Gaps = 1/46 (2%)
Frame = -3
Query: 431 IHGRGERSPRRWLQPRLAVPRQASTSVPRTPAKCCSP-TPLRSNSV 297
I+ GE+ P W PRL + Q P TP P TPL++ V
Sbjct: 511 IYVPGEKPPPPWAPPRLPLRLQRRLKRPETPTHDPDPETPLKARKV 556
>CR457259-1|CAG33540.1| 674|Homo sapiens PPP1R15A protein.
Length = 674
Score = 31.1 bits (67), Expect = 5.5
Identities = 17/46 (36%), Positives = 22/46 (47%), Gaps = 1/46 (2%)
Frame = -3
Query: 431 IHGRGERSPRRWLQPRLAVPRQASTSVPRTPAKCCSP-TPLRSNSV 297
I+ GE+ P W PRL + Q P TP P TPL++ V
Sbjct: 511 IYVPGEKPPPPWAPPRLPLRLQRRLKRPETPTHDPDPETPLKARKV 556
>BC003067-1|AAH03067.1| 674|Homo sapiens protein phosphatase 1,
regulatory (inhibitor) subunit 15A protein.
Length = 674
Score = 31.1 bits (67), Expect = 5.5
Identities = 17/46 (36%), Positives = 22/46 (47%), Gaps = 1/46 (2%)
Frame = -3
Query: 431 IHGRGERSPRRWLQPRLAVPRQASTSVPRTPAKCCSP-TPLRSNSV 297
I+ GE+ P W PRL + Q P TP P TPL++ V
Sbjct: 511 IYVPGEKPPPPWAPPRLPLRLQRRLKRPETPTHDPDPETPLKARKV 556
>AK001361-1|BAA91649.1| 674|Homo sapiens protein ( Homo sapiens
cDNA FLJ10499 fis, clone NT2RP2000346, weakly similar to
MYELOID DIFFERENTIATION PRIMARY RESPONSE PROTEIN MYD116.
).
Length = 674
Score = 31.1 bits (67), Expect = 5.5
Identities = 17/46 (36%), Positives = 22/46 (47%), Gaps = 1/46 (2%)
Frame = -3
Query: 431 IHGRGERSPRRWLQPRLAVPRQASTSVPRTPAKCCSP-TPLRSNSV 297
I+ GE+ P W PRL + Q P TP P TPL++ V
Sbjct: 511 IYVPGEKPPPPWAPPRLPLRLQRRLKRPETPTHDPDPETPLKARKV 556
>BC146774-1|AAI46775.1| 1114|Homo sapiens GPR124 protein protein.
Length = 1114
Score = 30.7 bits (66), Expect = 7.2
Identities = 16/55 (29%), Positives = 26/55 (47%), Gaps = 1/55 (1%)
Frame = +2
Query: 305 WNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNN-GSVSWIKRL 466
W +GEW C+ + + ++V+L T+ Y RV+NN G W + L
Sbjct: 314 WASGEWECTVSMAQGNASKKVEIVVLE----TSASYCPAERVANNRGDFRWPRTL 364
>AY181242-1|AAO27354.1| 1331|Homo sapiens G protein-coupled receptor
124 protein.
Length = 1331
Score = 30.7 bits (66), Expect = 7.2
Identities = 16/55 (29%), Positives = 26/55 (47%), Gaps = 1/55 (1%)
Frame = +2
Query: 305 WNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNN-GSVSWIKRL 466
W +GEW C+ + + ++V+L T+ Y RV+NN G W + L
Sbjct: 314 WASGEWECTVSMAQGNASKKVEIVVLE----TSASYCPAERVANNRGDFRWPRTL 364
>AK074099-1|BAB84925.1| 1310|Homo sapiens FLJ00170 protein protein.
Length = 1310
Score = 30.7 bits (66), Expect = 7.2
Identities = 16/55 (29%), Positives = 26/55 (47%), Gaps = 1/55 (1%)
Frame = +2
Query: 305 WNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNN-GSVSWIKRL 466
W +GEW C+ + + ++V+L T+ Y RV+NN G W + L
Sbjct: 293 WASGEWECTVSMAQGNASKKVEIVVLE----TSASYCPAERVANNRGDFRWPRTL 343
>AF378755-1|AAL11992.1| 1331|Homo sapiens tumor endothelial marker 5
precursor protein.
Length = 1331
Score = 30.7 bits (66), Expect = 7.2
Identities = 16/55 (29%), Positives = 26/55 (47%), Gaps = 1/55 (1%)
Frame = +2
Query: 305 WNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNN-GSVSWIKRL 466
W +GEW C+ + + ++V+L T+ Y RV+NN G W + L
Sbjct: 314 WASGEWECTVSMAQGNASKKVEIVVLE----TSASYCPAERVANNRGDFRWPRTL 364
>AB040964-1|BAA96055.2| 1206|Homo sapiens KIAA1531 protein protein.
Length = 1206
Score = 30.7 bits (66), Expect = 7.2
Identities = 16/55 (29%), Positives = 26/55 (47%), Gaps = 1/55 (1%)
Frame = +2
Query: 305 WNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNN-GSVSWIKRL 466
W +GEW C+ + + ++V+L T+ Y RV+NN G W + L
Sbjct: 406 WASGEWECTVSMAQGNASKKVEIVVLE----TSASYCPAERVANNRGDFRWPRTL 456
>AK122582-1|BAC56923.1| 1383|Homo sapiens FLJ00269 protein protein.
Length = 1383
Score = 30.3 bits (65), Expect = 9.5
Identities = 13/38 (34%), Positives = 18/38 (47%)
Frame = -3
Query: 428 HGRGERSPRRWLQPRLAVPRQASTSVPRTPAKCCSPTP 315
HG + SP W Q + + P + P P +CCS P
Sbjct: 256 HGGRDCSPTCWEQGKCSGPAEQEKRGPSFPKECCSQGP 293
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 133,377,051
Number of Sequences: 237096
Number of extensions: 3335270
Number of successful extensions: 12023
Number of sequences better than 10.0: 192
Number of HSP's better than 10.0 without gapping: 8444
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 11669
length of database: 76,859,062
effective HSP length: 90
effective length of database: 55,520,422
effective search space used: 11104084400
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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