Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BmNP02_FL5_L07
(861 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
AJ306454-1|CAC34819.1| 497|Homo sapiens neuronal nicotinic acet... 71 5e-12
Y08416-1|CAA69693.1| 498|Homo sapiens nicotinic acetylcholine r... 69 2e-11
U62439-1|AAB40117.1| 498|Homo sapiens nicotinic acetylcholine r... 69 2e-11
U48861-1|AAA92123.1| 498|Homo sapiens beta 4 nicotinic acetylch... 69 2e-11
BC096082-1|AAH96082.1| 498|Homo sapiens cholinergic receptor, n... 69 2e-11
BC096080-1|AAH96080.1| 498|Homo sapiens cholinergic receptor, n... 69 2e-11
AF306329-1|AAL02062.1| 498|Homo sapiens neuronal nicotinic acet... 69 2e-11
BT006897-1|AAP35543.1| 505|Homo sapiens cholinergic receptor, n... 67 9e-11
BT006646-1|AAP35292.1| 489|Homo sapiens cholinergic receptor, n... 67 9e-11
BC006114-1|AAH06114.1| 489|Homo sapiens CHRNA3 protein protein. 67 9e-11
BC002996-1|AAH02996.1| 505|Homo sapiens cholinergic receptor, n... 67 9e-11
BC001642-1|AAH01642.1| 505|Homo sapiens cholinergic receptor, n... 67 9e-11
BC000513-1|AAH00513.1| 505|Homo sapiens cholinergic receptor, n... 67 9e-11
AF385584-1|AAK68110.1| 489|Homo sapiens nicotinic cholinergic r... 67 9e-11
Y08418-1|CAA69695.1| 503|Homo sapiens nicotinic acetylcholine r... 66 2e-10
U62432-1|AAB40110.1| 504|Homo sapiens nicotinic acetylcholine r... 66 2e-10
M37981-1|AAA59942.1| 503|Homo sapiens neuronal nicotinic acetyl... 66 2e-10
BC098443-1|AAH98443.1| 504|Homo sapiens cholinergic receptor, n... 66 2e-10
AJ007783-1|CAA07682.1| 504|Homo sapiens nicotinic acetylcholine... 66 2e-10
Y08419-1|CAA69696.1| 468|Homo sapiens nicotinic acetylcholine r... 66 2e-10
U62434-1|AAB40112.1| 468|Homo sapiens nicotinic acetylcholine r... 66 2e-10
BC033639-1|AAH33639.1| 468|Homo sapiens cholinergic receptor, n... 66 2e-10
AJ306481-1|CAC34820.1| 468|Homo sapiens neuronal nicotinic acet... 66 2e-10
X53559-1|CAA37625.1| 474|Homo sapiens neuronal nicotinic acetyl... 65 3e-10
Y08417-1|CAA69694.1| 458|Homo sapiens nicotinic acetylcholine r... 65 4e-10
X67513-1|CAA47851.1| 423|Homo sapiens nicotinic acetylcholine ... 65 4e-10
U62438-1|AAB40116.1| 458|Homo sapiens nicotinic acetylcholine r... 65 4e-10
BC069788-1|AAH69788.1| 458|Homo sapiens cholinergic receptor, n... 65 4e-10
BC069703-1|AAH69703.1| 458|Homo sapiens cholinergic receptor, n... 65 4e-10
BC069681-1|AAH69681.1| 458|Homo sapiens cholinergic receptor, n... 65 4e-10
AF140765-1|AAD33063.1| 458|Homo sapiens neuronal acetylcholine ... 65 4e-10
X68275-1|CAA48336.1| 451|Homo sapiens nicotinic receptor beta 4... 64 5e-10
M83712-1|AAA58357.1| 468|Homo sapiens nicotinic receptor alpha ... 64 5e-10
M86383-1|AAC84176.1| 502|Homo sapiens nicotinic acetylcholine r... 64 8e-10
Y16281-1|CAA76154.1| 529|Homo sapiens nicotinic acetylcholine r... 63 1e-09
U62431-1|AAB40109.1| 529|Homo sapiens nicotinic acetylcholine r... 63 1e-09
Y08421-1|CAA69698.1| 627|Homo sapiens nicotinic acetylcholine r... 62 3e-09
X89741-1|CAA61893.1| 627|Homo sapiens neuronal acetylcholine re... 62 3e-09
U62433-1|AAB40111.1| 627|Homo sapiens nicotinic acetylcholine r... 62 3e-09
L35901-1|AAA64743.1| 627|Homo sapiens nicotinic acetylcholine r... 62 3e-09
DQ093071-1|AAY88737.1| 627|Homo sapiens cholinergic receptor, n... 62 3e-09
BC096290-1|AAH96290.1| 627|Homo sapiens cholinergic receptor, n... 62 3e-09
X87629-1|CAA60959.1| 602|Homo sapiens nicotinic acetylcholine r... 62 3e-09
Y16282-1|CAA76155.1| 494|Homo sapiens nicotinic acetylcholine r... 61 6e-09
U62435-1|AAB40113.1| 494|Homo sapiens nicotinic acetylcholine r... 61 6e-09
BC014456-1|AAH14456.1| 494|Homo sapiens cholinergic receptor, n... 61 6e-09
AB079251-1|BAC06855.1| 494|Homo sapiens Nicotinic acetylcholine... 61 6e-09
X14830-1|CAA32939.1| 501|Homo sapiens protein ( Human mRNA for ... 60 1e-08
BC011371-1|AAH11371.1| 501|Homo sapiens cholinergic receptor, n... 60 1e-08
AJ001935-1|CAA05108.1| 504|Homo sapiens CHRNB2 protein. 60 1e-08
Y08415-1|CAA69692.1| 502|Homo sapiens nicotinic acetylcholine r... 60 1e-08
X53179-1|CAA37320.1| 502|Homo sapiens precursor peptide (AA -25... 60 1e-08
U62437-1|AAB40115.1| 502|Homo sapiens nicotinic acetylcholine r... 60 1e-08
BC075041-1|AAH75041.1| 502|Homo sapiens cholinergic receptor, n... 60 1e-08
BC075040-1|AAH75040.1| 502|Homo sapiens cholinergic receptor, n... 60 1e-08
AL592078-3|CAI16184.1| 502|Homo sapiens cholinergic receptor, n... 60 1e-08
AF077186-1|AAD45422.1| 502|Homo sapiens neuronal nicotinic acet... 60 1e-08
DQ644022-1|ABG35128.1| 456|Homo sapiens 5-HT3 receptor subunit ... 59 2e-08
BC023553-1|AAH23553.1| 501|Homo sapiens cholinergic receptor, n... 59 2e-08
X66403-1|CAA47030.1| 493|Homo sapiens acetylcholine receptor ep... 58 3e-08
BC131799-1|AAI31800.1| 447|Homo sapiens 5-hydroxytryptamine (se... 58 3e-08
BC101185-1|AAI01186.1| 374|Homo sapiens HTR3E protein protein. 58 3e-08
BC101183-1|AAI01184.1| 471|Homo sapiens 5-hydroxytryptamine (se... 58 3e-08
BC101182-1|AAI01183.1| 471|Homo sapiens 5-hydroxytryptamine (se... 58 3e-08
AY159813-1|AAO38167.2| 471|Homo sapiens 5-hydroxytryptamine ser... 58 3e-08
AF105999-1|AAD24503.1| 493|Homo sapiens acetylcholine receptor ... 58 3e-08
AF459285-1|AAL66182.1| 447|Homo sapiens 5-hydroxytryptamine rec... 58 4e-08
Y00762-1|CAA68731.1| 457|Homo sapiens protein ( Human mRNA for ... 58 5e-08
X02502-1|CAA26344.1| 457|Homo sapiens acetylcholine receptor pr... 58 5e-08
X01715-1|CAA25861.1| 520|Homo sapiens acetylcholine receptor ga... 58 5e-08
S77094-1|AAD14247.1| 457|Homo sapiens nicotinic acetylcholine r... 58 5e-08
BC006314-1|AAH06314.1| 269|Homo sapiens CHRNA1 protein protein. 58 5e-08
AC092165-3|AAY24103.1| 520|Homo sapiens unknown protein. 58 5e-08
AC018890-1|AAY14687.1| 457|Homo sapiens unknown protein. 58 5e-08
AY349353-1|AAQ93477.1| 456|Homo sapiens 5-HT3c1 serotonin recep... 56 1e-07
AY349352-1|AAQ93476.1| 441|Homo sapiens 5-HT3c1 serotonin recep... 56 1e-07
BC110597-1|AAI10598.1| 411|Homo sapiens ligand-gated ion channe... 55 4e-07
AJ295237-1|CAC16144.1| 450|Homo sapiens neuronal nicotinic acet... 55 4e-07
AJ278118-1|CAC20435.1| 450|Homo sapiens neuronal nicotinic acet... 55 4e-07
AF512521-1|AAO20969.1| 411|Homo sapiens ligand-gated ion channe... 55 4e-07
AF327367-1|AAK14333.1| 450|Homo sapiens nicotinic acetylcholine... 55 4e-07
AF199235-1|AAG00795.2| 450|Homo sapiens nicotinic acetylcholine... 55 4e-07
BC113575-1|AAI13576.1| 479|Homo sapiens cholinergic receptor, n... 54 5e-07
BC113549-1|AAI13550.1| 479|Homo sapiens cholinergic receptor, n... 54 5e-07
AY123244-1|AAM74523.1| 479|Homo sapiens nicotinic acetylcholine... 54 5e-07
AJ243342-1|CAB65091.1| 479|Homo sapiens nicotinic acetylcholine... 54 5e-07
AF227732-1|AAF61920.1| 470|Homo sapiens nicotinic acetylcholine... 54 5e-07
AC118275-1|AAY40986.1| 479|Homo sapiens unknown protein. 54 5e-07
AB223030-1|BAE19924.1| 411|Homo sapiens ligand-gated ion-channe... 54 5e-07
S82612-1|AAB37533.2| 478|Homo sapiens 5-hydroxytryptamine type ... 54 9e-07
S77554-1|AAB33983.1| 474|Homo sapiens GABAA receptor beta 2 sub... 54 9e-07
S77553-1|AAB33982.1| 512|Homo sapiens GABAA receptor beta 2 sub... 54 9e-07
S67368-1|AAB29370.1| 474|Homo sapiens gamma-aminobutyric acid A... 54 9e-07
BC105639-1|AAI05640.1| 474|Homo sapiens GABRB2 protein protein. 54 9e-07
BC099719-1|AAH99719.1| 474|Homo sapiens GABRB2 protein protein. 54 9e-07
BC099705-1|AAH99705.1| 474|Homo sapiens GABRB2 protein protein. 54 9e-07
AJ003080-1|CAA05853.1| 238|Homo sapiens serotonin receptor prot... 54 9e-07
M59216-1|AAA35862.1| 474|Homo sapiens gamma-aminobutyric acid r... 53 1e-06
L08485-1|AAA58490.1| 462|Homo sapiens GABA-benzodiazepine recep... 53 2e-06
D49394-1|BAA08387.1| 478|Homo sapiens serotonin 5-HT3 receptor ... 53 2e-06
BT009830-1|AAP88832.1| 462|Homo sapiens gamma-aminobutyric acid... 53 2e-06
BT007204-1|AAP35868.1| 484|Homo sapiens 5-hydroxytryptamine (se... 53 2e-06
BC113422-1|AAI13423.1| 462|Homo sapiens gamma-aminobutyric acid... 53 2e-06
BC111979-1|AAI11980.1| 462|Homo sapiens gamma-aminobutyric acid... 53 2e-06
BC004453-1|AAH04453.2| 478|Homo sapiens 5-hydroxytryptamine (se... 53 2e-06
BC002354-1|AAH02354.1| 478|Homo sapiens 5-hydroxytryptamine (se... 53 2e-06
AJ005205-1|CAA06442.3| 478|Homo sapiens serotonin 3 receptor pr... 53 2e-06
AJ003079-1|CAA05852.1| 478|Homo sapiens 5-hydroxytryptamine3 re... 53 2e-06
AJ003078-1|CAA05851.1| 510|Homo sapiens serotonin receptor prot... 53 2e-06
AF498984-1|AAM21131.1| 478|Homo sapiens 5-hydroxytryptamine rec... 53 2e-06
Z23141-1|CAA80672.1| 479|Homo sapiens cholinergic receptor, nic... 52 2e-06
Y08420-1|CAA69697.1| 502|Homo sapiens nicotinic acetylcholine r... 52 2e-06
X70297-1|CAA49778.1| 502|Homo sapiens neuronal nicotinic acetyl... 52 2e-06
X14767-1|CAA32875.1| 474|Homo sapiens GABA-A receptor beta 1 su... 52 2e-06
U62436-1|AAB40114.1| 502|Homo sapiens nicotinic acetylcholine r... 52 2e-06
AJ586911-1|CAE52911.1| 502|Homo sapiens nicotinic acetylcholine... 52 2e-06
X55019-1|CAA38759.1| 517|Homo sapiens acetylcholine receptor de... 52 4e-06
BC093925-1|AAH93925.1| 517|Homo sapiens cholinergic receptor, n... 52 4e-06
BC093923-1|AAH93923.1| 517|Homo sapiens cholinergic receptor, n... 52 4e-06
AC092165-2|AAY24102.1| 517|Homo sapiens unknown protein. 52 4e-06
U40583-1|AAA83561.1| 502|Homo sapiens alpha 7 neuronal nicotini... 51 5e-06
AK122638-1|BAC85499.1| 266|Homo sapiens yte protein of 76kDa) (... 51 5e-06
AF385585-1|AAK68111.1| 502|Homo sapiens nicotinic cholinergic r... 51 5e-06
BC028629-1|AAH28629.1| 492|Homo sapiens gamma-aminobutyric acid... 50 1e-05
S82769-1|AAB39369.1| 467|Homo sapiens GABAA receptor gamma 3 su... 50 1e-05
S62908-1|AAB27279.1| 492|Homo sapiens gamma-aminobutyric acidA ... 50 1e-05
AF269144-1|AAF99698.1| 467|Homo sapiens GABAA receptor gamma 3 ... 50 1e-05
AF228458-1|AAF63215.1| 449|Homo sapiens GABAA receptor gamma 3 ... 50 1e-05
AF166361-1|AAG12455.1| 492|Homo sapiens GABA receptor subunit a... 50 1e-05
U77731-2|AAB38273.1| 360|Homo sapiens glycine receptor alpha 2B... 49 3e-05
CR450343-1|CAG29339.1| 452|Homo sapiens GLRA2 protein. 49 3e-05
BC111802-1|AAI11803.1| 465|Homo sapiens CHRNG protein protein. 49 3e-05
AY437084-1|AAR87843.1| 452|Homo sapiens glycine receptor alpha2... 49 3e-05
X52008-1|CAA36257.1| 452|Homo sapiens inhibitory glycine recept... 48 3e-05
U77731-1|AAB38272.1| 360|Homo sapiens glycine receptor alpha 2 ... 48 3e-05
BC032864-1|AAH32864.1| 452|Homo sapiens glycine receptor, alpha... 48 3e-05
AY437083-1|AAR87842.1| 452|Homo sapiens glycine receptor alpha2... 48 3e-05
AF053495-1|AAC35290.1| 452|Homo sapiens glycine receptor alpha ... 48 3e-05
S81944-1|AAB36480.1| 453|Homo sapiens gamma-aminobutyric acid t... 48 4e-05
BC099641-1|AAH99641.1| 453|Homo sapiens gamma-aminobutyric acid... 48 4e-05
BC099640-1|AAH99640.1| 453|Homo sapiens gamma-aminobutyric acid... 48 4e-05
BC096242-1|AAH96242.1| 453|Homo sapiens gamma-aminobutyric acid... 48 4e-05
BC096241-1|AAH96241.1| 453|Homo sapiens gamma-aminobutyric acid... 48 4e-05
BC022449-1|AAH22449.1| 474|Homo sapiens gamma-aminobutyric acid... 48 4e-05
U30461-1|AAB52519.1| 554|Homo sapiens GABAA receptor subunit al... 47 8e-05
BC035055-1|AAH35055.1| 554|Homo sapiens gamma-aminobutyric acid... 47 8e-05
BC096083-1|AAH96083.1| 198|Homo sapiens CHRNB4 protein protein. 47 1e-04
BC096081-1|AAH96081.1| 198|Homo sapiens CHRNB4 protein protein. 47 1e-04
U95367-1|AAC51357.1| 440|Homo sapiens GABA-A receptor pi subuni... 46 2e-04
BC109211-1|AAI09212.1| 632|Homo sapiens gamma-aminobutyric acid... 46 2e-04
BC109210-1|AAI09211.1| 632|Homo sapiens gamma-aminobutyric acid... 46 2e-04
BC109106-1|AAI09107.1| 440|Homo sapiens gamma-aminobutyric acid... 46 2e-04
BC109105-1|AAI09106.1| 440|Homo sapiens gamma-aminobutyric acid... 46 2e-04
BC074865-1|AAH74865.1| 440|Homo sapiens gamma-aminobutyric acid... 46 2e-04
BC074810-1|AAH74810.1| 440|Homo sapiens gamma-aminobutyric acid... 46 2e-04
BC033801-1|AAH33801.1| 452|Homo sapiens gamma-aminobutyric acid... 46 2e-04
AL391845-4|CAI15436.1| 452|Homo sapiens gamma-aminobutyric acid... 46 2e-04
AF189259-1|AAF70380.1| 632|Homo sapiens GABA-A receptor theta s... 46 2e-04
AF144648-1|AAD51172.1| 627|Homo sapiens GABA-A receptor theta p... 46 2e-04
AF016917-1|AAB70007.1| 452|Homo sapiens GABA-A receptor delta s... 46 2e-04
AF009702-1|AAC24194.1| 440|Homo sapiens GABA-A receptor pi subu... 46 2e-04
U93917-1|AAC39917.1| 449|Homo sapiens glycine receptor alpha 3 ... 45 4e-04
BC114947-1|AAI14948.1| 457|Homo sapiens GLRA1 protein protein. 45 4e-04
BC074980-1|AAH74980.1| 449|Homo sapiens glycine receptor, alpha... 45 4e-04
BC036086-1|AAH36086.1| 464|Homo sapiens glycine receptor, alpha... 45 4e-04
AF017724-1|AAC39919.1| 465|Homo sapiens glycine receptor alpha ... 45 4e-04
X52009-1|CAA36258.1| 449|Homo sapiens inhibitory glycine recept... 44 5e-04
BC074795-1|AAH74795.1| 467|Homo sapiens gamma-aminobutyric acid... 44 5e-04
BC069348-1|AAH69348.1| 467|Homo sapiens gamma-aminobutyric acid... 44 5e-04
BC059389-1|AAH59389.1| 475|Homo sapiens gamma-aminobutyric acid... 44 5e-04
AF165124-1|AAD50273.1| 467|Homo sapiens gamma-aminobutyric acid... 44 5e-04
BC031087-1|AAH31087.1| 465|Homo sapiens gamma-aminobutyric acid... 44 7e-04
X15376-1|CAA33437.1| 467|Homo sapiens GABA-A receptor gamma 2 s... 44 0.001
Z93848-1|CAI41994.1| 376|Homo sapiens glycine receptor, alpha 4... 42 0.002
AL049610-1|CAI42158.1| 376|Homo sapiens glycine receptor, alpha... 42 0.002
BC114967-1|AAI14968.1| 366|Homo sapiens GLRA1 protein protein. 41 0.005
AB209359-1|BAD92596.1| 533|Homo sapiens cholinergic receptor, n... 37 0.11
BC096291-1|AAH96291.1| 556|Homo sapiens CHRNA4 protein protein. 36 0.19
AY049075-1|AAL06603.1| 514|Homo sapiens dynein heavy chain prot... 32 2.3
Y00285-1|CAA68395.1| 2491|Homo sapiens protein ( Human mRNA for ... 30 9.4
J03528-1|AAA59866.1| 2491|Homo sapiens mannose 6-phosphate recep... 30 9.4
AY293855-1|AAP37954.1| 2491|Homo sapiens insulin-like growth fac... 30 9.4
AF109291-1|AAF16870.1| 2491|Homo sapiens insulin-like growth fac... 30 9.4
AB209668-1|BAD92905.1| 2414|Homo sapiens Insulin-like growth fac... 30 9.4
>AJ306454-1|CAC34819.1| 497|Homo sapiens neuronal nicotinic
acetylcholine receptor beta-4 subunit protein.
Length = 497
Score = 70.9 bits (166), Expect = 5e-12
Identities = 54/195 (27%), Positives = 89/195 (45%), Gaps = 11/195 (5%)
Frame = +1
Query: 67 LLPFLLTCAIASAAECENATSLSLMIDSLL--ATYDRESPP--DSKIVVNLTLHLRHA-- 228
L+ F L A+ C A + ++D LL Y+ P S ++++ L L A
Sbjct: 7 LVLFFLV-ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQL 65
Query: 229 -NIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTA 402
++ E E + L+ W D RL+WN+ + G + + ++R+W PD+VL N T
Sbjct: 66 ISVNEREQIMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNDGTYE 125
Query: 403 GDYALRARVSNNGSVSXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVID 582
V +NGSV + + +++ +P D Q CT KF S ++ E+D V+
Sbjct: 126 VSVYTNLIVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRSWTYDHTEIDMVLM 185
Query: 583 KRIYSMFE---SGAW 618
SM + SG W
Sbjct: 186 TPTASMDDFTPSGEW 200
>Y08416-1|CAA69693.1| 498|Homo sapiens nicotinic acetylcholine
receptor beta4 subunit precursor protein.
Length = 498
Score = 68.9 bits (161), Expect = 2e-11
Identities = 55/196 (28%), Positives = 90/196 (45%), Gaps = 12/196 (6%)
Frame = +1
Query: 67 LLPFLLTCAIASAAECENATSLSLMIDSLL--ATYDRESPP--DSKIVVNLTLHLRHA-- 228
L+ F L A+ C A + ++D LL Y+ P S ++++ L L A
Sbjct: 7 LVLFFLV-ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQL 65
Query: 229 -NIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATT 399
++ E E + L+ W D RL+WN+ + G + + ++R+W PD+VL N A T
Sbjct: 66 ISVNEREQIMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNADGTY 125
Query: 400 AGDYALRARVSNNGSVSXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVI 579
V +NGSV + + +++ +P D Q CT KF S ++ E+D V+
Sbjct: 126 EVSVYTNLIVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRSWTYDHTEIDMVL 185
Query: 580 DKRIYSMFE---SGAW 618
SM + SG W
Sbjct: 186 MTPTASMDDFTPSGEW 201
>U62439-1|AAB40117.1| 498|Homo sapiens nicotinic acetylcholine
receptor beta4 subunit precursor protein.
Length = 498
Score = 68.9 bits (161), Expect = 2e-11
Identities = 55/196 (28%), Positives = 90/196 (45%), Gaps = 12/196 (6%)
Frame = +1
Query: 67 LLPFLLTCAIASAAECENATSLSLMIDSLL--ATYDRESPP--DSKIVVNLTLHLRHA-- 228
L+ F L A+ C A + ++D LL Y+ P S ++++ L L A
Sbjct: 7 LVLFFLV-ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQL 65
Query: 229 -NIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATT 399
++ E E + L+ W D RL+WN+ + G + + ++R+W PD+VL N A T
Sbjct: 66 ISVNEREQIMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNADGTY 125
Query: 400 AGDYALRARVSNNGSVSXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVI 579
V +NGSV + + +++ +P D Q CT KF S ++ E+D V+
Sbjct: 126 EVSVYTNLIVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRSWTYDHTEIDMVL 185
Query: 580 DKRIYSMFE---SGAW 618
SM + SG W
Sbjct: 186 MTPTASMDDFTPSGEW 201
>U48861-1|AAA92123.1| 498|Homo sapiens beta 4 nicotinic
acetylcholine receptor subunit protein.
Length = 498
Score = 68.9 bits (161), Expect = 2e-11
Identities = 55/196 (28%), Positives = 90/196 (45%), Gaps = 12/196 (6%)
Frame = +1
Query: 67 LLPFLLTCAIASAAECENATSLSLMIDSLL--ATYDRESPP--DSKIVVNLTLHLRHA-- 228
L+ F L A+ C A + ++D LL Y+ P S ++++ L L A
Sbjct: 7 LVLFFLV-ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQL 65
Query: 229 -NIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATT 399
++ E E + L+ W D RL+WN+ + G + + ++R+W PD+VL N A T
Sbjct: 66 ISVNEREQIMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNADGTY 125
Query: 400 AGDYALRARVSNNGSVSXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVI 579
V +NGSV + + +++ +P D Q CT KF S ++ E+D V+
Sbjct: 126 EVSVYTNLIVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRSWTYDHTEIDMVL 185
Query: 580 DKRIYSMFE---SGAW 618
SM + SG W
Sbjct: 186 MTPTASMDDFTPSGEW 201
>BC096082-1|AAH96082.1| 498|Homo sapiens cholinergic receptor,
nicotinic, beta 4 protein.
Length = 498
Score = 68.9 bits (161), Expect = 2e-11
Identities = 55/196 (28%), Positives = 90/196 (45%), Gaps = 12/196 (6%)
Frame = +1
Query: 67 LLPFLLTCAIASAAECENATSLSLMIDSLL--ATYDRESPP--DSKIVVNLTLHLRHA-- 228
L+ F L A+ C A + ++D LL Y+ P S ++++ L L A
Sbjct: 7 LVLFFLV-ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQL 65
Query: 229 -NIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATT 399
++ E E + L+ W D RL+WN+ + G + + ++R+W PD+VL N A T
Sbjct: 66 ISVNEREQIMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNADGTY 125
Query: 400 AGDYALRARVSNNGSVSXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVI 579
V +NGSV + + +++ +P D Q CT KF S ++ E+D V+
Sbjct: 126 EVSVYTNLIVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRSWTYDHTEIDMVL 185
Query: 580 DKRIYSMFE---SGAW 618
SM + SG W
Sbjct: 186 MTPTASMDDFTPSGEW 201
>BC096080-1|AAH96080.1| 498|Homo sapiens cholinergic receptor,
nicotinic, beta 4 protein.
Length = 498
Score = 68.9 bits (161), Expect = 2e-11
Identities = 55/196 (28%), Positives = 90/196 (45%), Gaps = 12/196 (6%)
Frame = +1
Query: 67 LLPFLLTCAIASAAECENATSLSLMIDSLL--ATYDRESPP--DSKIVVNLTLHLRHA-- 228
L+ F L A+ C A + ++D LL Y+ P S ++++ L L A
Sbjct: 7 LVLFFLV-ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQL 65
Query: 229 -NIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATT 399
++ E E + L+ W D RL+WN+ + G + + ++R+W PD+VL N A T
Sbjct: 66 ISVNEREQIMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNADGTY 125
Query: 400 AGDYALRARVSNNGSVSXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVI 579
V +NGSV + + +++ +P D Q CT KF S ++ E+D V+
Sbjct: 126 EVSVYTNLIVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRSWTYDHTEIDMVL 185
Query: 580 DKRIYSMFE---SGAW 618
SM + SG W
Sbjct: 186 MTPTASMDDFTPSGEW 201
>AF306329-1|AAL02062.1| 498|Homo sapiens neuronal nicotinic
acetylcholine receptor beta 4 subunit protein.
Length = 498
Score = 68.9 bits (161), Expect = 2e-11
Identities = 55/196 (28%), Positives = 90/196 (45%), Gaps = 12/196 (6%)
Frame = +1
Query: 67 LLPFLLTCAIASAAECENATSLSLMIDSLL--ATYDRESPP--DSKIVVNLTLHLRHA-- 228
L+ F L A+ C A + ++D LL Y+ P S ++++ L L A
Sbjct: 7 LVLFFLV-ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQL 65
Query: 229 -NIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATT 399
++ E E + L+ W D RL+WN+ + G + + ++R+W PD+VL N A T
Sbjct: 66 ISVNEREQIMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNADGTY 125
Query: 400 AGDYALRARVSNNGSVSXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVI 579
V +NGSV + + +++ +P D Q CT KF S ++ E+D V+
Sbjct: 126 EVSVYTNLIVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRSWTYDHTEIDMVL 185
Query: 580 DKRIYSMFE---SGAW 618
SM + SG W
Sbjct: 186 MTPTASMDDFTPSGEW 201
>BT006897-1|AAP35543.1| 505|Homo sapiens cholinergic receptor,
nicotinic, alpha polypeptide 3 protein.
Length = 505
Score = 66.9 bits (156), Expect = 9e-11
Identities = 48/199 (24%), Positives = 91/199 (45%), Gaps = 8/199 (4%)
Frame = +1
Query: 46 MSTTYIILLPFLLTCAIASAAECENATSLSLMID--SLLATYDRESPPDSKIVVNLTLHL 219
+S ++LL L +A A+E E+ L D ++ S P ++++ + +
Sbjct: 12 LSPPRLLLLLLLSLLPVARASEAEHRLFERLFEDYNEIIRPVANVSDP---VIIHFEVSM 68
Query: 220 RH-ANIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AA 390
+ E + L+ W D +L WN ++G + ++ V ++++W+PD+VL N A
Sbjct: 69 SQLVKVDEVNQIMETNLWLKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAV 128
Query: 391 ATTAGDYALRARVSNNGSVSXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 570
D +A + G V+ I + + + +P D Q CT KFGS ++ ++D
Sbjct: 129 GDFQVDDKTKALLKYTGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKID 188
Query: 571 FVI---DKRIYSMFESGAW 618
V+ + +ESG W
Sbjct: 189 LVLIGSSMNLKDYWESGEW 207
>BT006646-1|AAP35292.1| 489|Homo sapiens cholinergic receptor,
nicotinic, alpha polypeptide 3 protein.
Length = 489
Score = 66.9 bits (156), Expect = 9e-11
Identities = 48/199 (24%), Positives = 91/199 (45%), Gaps = 8/199 (4%)
Frame = +1
Query: 46 MSTTYIILLPFLLTCAIASAAECENATSLSLMID--SLLATYDRESPPDSKIVVNLTLHL 219
+S ++LL L +A A+E E+ L D ++ S P ++++ + +
Sbjct: 12 LSPPRLLLLLLLSLLPVARASEAEHRLFERLFEDYNEIIRPVANVSDP---VIIHFEVSM 68
Query: 220 RH-ANIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AA 390
+ E + L+ W D +L WN ++G + ++ V ++++W+PD+VL N A
Sbjct: 69 SQLVKVDEVNQIMETNLWLKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAV 128
Query: 391 ATTAGDYALRARVSNNGSVSXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 570
D +A + G V+ I + + + +P D Q CT KFGS ++ ++D
Sbjct: 129 GDFQVDDKTKALLKYTGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKID 188
Query: 571 FVI---DKRIYSMFESGAW 618
V+ + +ESG W
Sbjct: 189 LVLIGSSMNLKDYWESGEW 207
>BC006114-1|AAH06114.1| 489|Homo sapiens CHRNA3 protein protein.
Length = 489
Score = 66.9 bits (156), Expect = 9e-11
Identities = 48/199 (24%), Positives = 91/199 (45%), Gaps = 8/199 (4%)
Frame = +1
Query: 46 MSTTYIILLPFLLTCAIASAAECENATSLSLMID--SLLATYDRESPPDSKIVVNLTLHL 219
+S ++LL L +A A+E E+ L D ++ S P ++++ + +
Sbjct: 12 LSPPRLLLLLLLSLLPVARASEAEHRLFERLFEDYNEIIRPVANVSDP---VIIHFEVSM 68
Query: 220 RH-ANIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AA 390
+ E + L+ W D +L WN ++G + ++ V ++++W+PD+VL N A
Sbjct: 69 SQLVKVDEVNQIMETNLWLKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAV 128
Query: 391 ATTAGDYALRARVSNNGSVSXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 570
D +A + G V+ I + + + +P D Q CT KFGS ++ ++D
Sbjct: 129 GDFQVDDKTKALLKYTGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKID 188
Query: 571 FVI---DKRIYSMFESGAW 618
V+ + +ESG W
Sbjct: 189 LVLIGSSMNLKDYWESGEW 207
>BC002996-1|AAH02996.1| 505|Homo sapiens cholinergic receptor,
nicotinic, alpha 3 protein.
Length = 505
Score = 66.9 bits (156), Expect = 9e-11
Identities = 48/199 (24%), Positives = 91/199 (45%), Gaps = 8/199 (4%)
Frame = +1
Query: 46 MSTTYIILLPFLLTCAIASAAECENATSLSLMID--SLLATYDRESPPDSKIVVNLTLHL 219
+S ++LL L +A A+E E+ L D ++ S P ++++ + +
Sbjct: 12 LSPPRLLLLLLLSLLPVARASEAEHRLFERLFEDYNEIIRPVANVSDP---VIIHFEVSM 68
Query: 220 RH-ANIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AA 390
+ E + L+ W D +L WN ++G + ++ V ++++W+PD+VL N A
Sbjct: 69 SQLVKVDEVNQIMETNLWLKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAV 128
Query: 391 ATTAGDYALRARVSNNGSVSXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 570
D +A + G V+ I + + + +P D Q CT KFGS ++ ++D
Sbjct: 129 GDFQVDDKTKALLKYTGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKID 188
Query: 571 FVI---DKRIYSMFESGAW 618
V+ + +ESG W
Sbjct: 189 LVLIGSSMNLKDYWESGEW 207
>BC001642-1|AAH01642.1| 505|Homo sapiens cholinergic receptor,
nicotinic, alpha 3 protein.
Length = 505
Score = 66.9 bits (156), Expect = 9e-11
Identities = 48/199 (24%), Positives = 91/199 (45%), Gaps = 8/199 (4%)
Frame = +1
Query: 46 MSTTYIILLPFLLTCAIASAAECENATSLSLMID--SLLATYDRESPPDSKIVVNLTLHL 219
+S ++LL L +A A+E E+ L D ++ S P ++++ + +
Sbjct: 12 LSPPRLLLLLLLSLLPVARASEAEHRLFERLFEDYNEIIRPVANVSDP---VIIHFEVSM 68
Query: 220 RH-ANIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AA 390
+ E + L+ W D +L WN ++G + ++ V ++++W+PD+VL N A
Sbjct: 69 SQLVKVDEVNQIMETNLWLKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAV 128
Query: 391 ATTAGDYALRARVSNNGSVSXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 570
D +A + G V+ I + + + +P D Q CT KFGS ++ ++D
Sbjct: 129 GDFQVDDKTKALLKYTGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKID 188
Query: 571 FVI---DKRIYSMFESGAW 618
V+ + +ESG W
Sbjct: 189 LVLIGSSMNLKDYWESGEW 207
>BC000513-1|AAH00513.1| 505|Homo sapiens cholinergic receptor,
nicotinic, alpha 3 protein.
Length = 505
Score = 66.9 bits (156), Expect = 9e-11
Identities = 48/199 (24%), Positives = 91/199 (45%), Gaps = 8/199 (4%)
Frame = +1
Query: 46 MSTTYIILLPFLLTCAIASAAECENATSLSLMID--SLLATYDRESPPDSKIVVNLTLHL 219
+S ++LL L +A A+E E+ L D ++ S P ++++ + +
Sbjct: 12 LSPPRLLLLLLLSLLPVARASEAEHRLFERLFEDYNEIIRPVANVSDP---VIIHFEVSM 68
Query: 220 RH-ANIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AA 390
+ E + L+ W D +L WN ++G + ++ V ++++W+PD+VL N A
Sbjct: 69 SQLVKVDEVNQIMETNLWLKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAV 128
Query: 391 ATTAGDYALRARVSNNGSVSXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 570
D +A + G V+ I + + + +P D Q CT KFGS ++ ++D
Sbjct: 129 GDFQVDDKTKALLKYTGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKID 188
Query: 571 FVI---DKRIYSMFESGAW 618
V+ + +ESG W
Sbjct: 189 LVLIGSSMNLKDYWESGEW 207
>AF385584-1|AAK68110.1| 489|Homo sapiens nicotinic cholinergic
receptor alpha 3 protein.
Length = 489
Score = 66.9 bits (156), Expect = 9e-11
Identities = 48/199 (24%), Positives = 91/199 (45%), Gaps = 8/199 (4%)
Frame = +1
Query: 46 MSTTYIILLPFLLTCAIASAAECENATSLSLMID--SLLATYDRESPPDSKIVVNLTLHL 219
+S ++LL L +A A+E E+ L D ++ S P ++++ + +
Sbjct: 6 LSPPRLLLLLLLSLLPVARASEAEHRLFERLFEDYNEIIRPVANVSDP---VIIHFEVSM 62
Query: 220 RH-ANIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AA 390
+ E + L+ W D +L WN ++G + ++ V ++++W+PD+VL N A
Sbjct: 63 SQLVKVDEVNQIMETNLWLKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAV 122
Query: 391 ATTAGDYALRARVSNNGSVSXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 570
D +A + G V+ I + + + +P D Q CT KFGS ++ ++D
Sbjct: 123 GDFQVDDKTKALLKYTGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKID 182
Query: 571 FVI---DKRIYSMFESGAW 618
V+ + +ESG W
Sbjct: 183 LVLIGSSMNLKDYWESGEW 201
>Y08418-1|CAA69695.1| 503|Homo sapiens nicotinic acetylcholine
receptor alpha3 subunit precursor protein.
Length = 503
Score = 66.1 bits (154), Expect = 2e-10
Identities = 48/192 (25%), Positives = 88/192 (45%), Gaps = 6/192 (3%)
Frame = +1
Query: 61 IILLPFLLTCAIASAAECENATSLSLMIDSLLATYDRESPPDSKIVVNLTLHLRH-ANIR 237
++LL LL A AS AE L + ++ S P ++++ + + +
Sbjct: 17 LLLLLSLLPVARASEAEHRLFERLFEDYNEIIRPVANVSDP---VIIHFEVSMSQLVKVD 73
Query: 238 ESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDY 411
E + L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D
Sbjct: 74 EVNQIMETNLWLKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDD 133
Query: 412 ALRARVSNNGSVSXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVI---D 582
+A + G V+ I + + + +P D Q CT KFGS ++ ++D V+
Sbjct: 134 KTKALLKYTGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVLIGSS 193
Query: 583 KRIYSMFESGAW 618
+ +ESG W
Sbjct: 194 MNLKDYWESGEW 205
>U62432-1|AAB40110.1| 504|Homo sapiens nicotinic acetylcholine
receptor alpha3 subunit precursor protein.
Length = 504
Score = 66.1 bits (154), Expect = 2e-10
Identities = 48/192 (25%), Positives = 88/192 (45%), Gaps = 6/192 (3%)
Frame = +1
Query: 61 IILLPFLLTCAIASAAECENATSLSLMIDSLLATYDRESPPDSKIVVNLTLHLRH-ANIR 237
++LL LL A AS AE L + ++ S P ++++ + + +
Sbjct: 18 LLLLLSLLPVARASEAEHRLFERLFEDYNEIIRPVANVSDP---VIIHFEVSMSQLVKVD 74
Query: 238 ESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDY 411
E + L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D
Sbjct: 75 EVNQIMETNLWLKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDD 134
Query: 412 ALRARVSNNGSVSXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVI---D 582
+A + G V+ I + + + +P D Q CT KFGS ++ ++D V+
Sbjct: 135 KTKALLKYTGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVLIGSS 194
Query: 583 KRIYSMFESGAW 618
+ +ESG W
Sbjct: 195 MNLKDYWESGEW 206
>M37981-1|AAA59942.1| 503|Homo sapiens neuronal nicotinic
acetylcholine receptor protein.
Length = 503
Score = 66.1 bits (154), Expect = 2e-10
Identities = 48/192 (25%), Positives = 88/192 (45%), Gaps = 6/192 (3%)
Frame = +1
Query: 61 IILLPFLLTCAIASAAECENATSLSLMIDSLLATYDRESPPDSKIVVNLTLHLRH-ANIR 237
++LL LL A AS AE L + ++ S P ++++ + + +
Sbjct: 17 LLLLLSLLPVARASEAEHRLFERLFEDYNEIIRPVANVSDP---VIIHFEVSMSQLVKVD 73
Query: 238 ESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDY 411
E + L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D
Sbjct: 74 EVNQIMETNLWLKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDD 133
Query: 412 ALRARVSNNGSVSXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVI---D 582
+A + G V+ I + + + +P D Q CT KFGS ++ ++D V+
Sbjct: 134 KTKALLKYTGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVLIGSS 193
Query: 583 KRIYSMFESGAW 618
+ +ESG W
Sbjct: 194 MNLKDYWESGEW 205
>BC098443-1|AAH98443.1| 504|Homo sapiens cholinergic receptor,
nicotinic, alpha 3 protein.
Length = 504
Score = 66.1 bits (154), Expect = 2e-10
Identities = 48/192 (25%), Positives = 88/192 (45%), Gaps = 6/192 (3%)
Frame = +1
Query: 61 IILLPFLLTCAIASAAECENATSLSLMIDSLLATYDRESPPDSKIVVNLTLHLRH-ANIR 237
++LL LL A AS AE L + ++ S P ++++ + + +
Sbjct: 18 LLLLLSLLPVARASEAEHRLFERLFEDYNEIIRPVANVSDP---VIIHFEVSMSQLVKVD 74
Query: 238 ESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDY 411
E + L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D
Sbjct: 75 EVNQIMETNLWLKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDD 134
Query: 412 ALRARVSNNGSVSXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVI---D 582
+A + G V+ I + + + +P D Q CT KFGS ++ ++D V+
Sbjct: 135 KTKALLKYTGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVLIGSS 194
Query: 583 KRIYSMFESGAW 618
+ +ESG W
Sbjct: 195 MNLKDYWESGEW 206
>AJ007783-1|CAA07682.1| 504|Homo sapiens nicotinic acetylcholine
receptor alpha-3 subunit protein.
Length = 504
Score = 66.1 bits (154), Expect = 2e-10
Identities = 48/192 (25%), Positives = 88/192 (45%), Gaps = 6/192 (3%)
Frame = +1
Query: 61 IILLPFLLTCAIASAAECENATSLSLMIDSLLATYDRESPPDSKIVVNLTLHLRH-ANIR 237
++LL LL A AS AE L + ++ S P ++++ + + +
Sbjct: 18 LLLLLSLLPVARASEAEHRLFERLFEDYNEIIRPVANVSDP---VIIHFEVSMSQLVKVD 74
Query: 238 ESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDY 411
E + L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D
Sbjct: 75 EVNQIMETNLWLKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDD 134
Query: 412 ALRARVSNNGSVSXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVI---D 582
+A + G V+ I + + + +P D Q CT KFGS ++ ++D V+
Sbjct: 135 KTKALLKYTGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVLIGSS 194
Query: 583 KRIYSMFESGAW 618
+ +ESG W
Sbjct: 195 MNLKDYWESGEW 206
>Y08419-1|CAA69696.1| 468|Homo sapiens nicotinic acetylcholine
receptor alpha5 subunit precursor protein.
Length = 468
Score = 65.7 bits (153), Expect = 2e-10
Identities = 42/171 (24%), Positives = 80/171 (46%), Gaps = 11/171 (6%)
Frame = +1
Query: 139 MIDSLLATYDRESPP----DSKIVVNLTLHLRH-ANIRESESTVRILADLQMNWIDKRLS 303
++ L Y+R P + KI + L + ++ E + L+ WID +L
Sbjct: 50 LLKDLFQDYERWVRPVEHLNDKIKIKFGLAISQLVDVDEKNQLMTTNVWLKQEWIDVKLR 109
Query: 304 WNAGEWG-CSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVSXIKRLDISTP 480
WN ++G V S+ +W PD+VL + A + + + NG+V+ + +
Sbjct: 110 WNPDDYGGIKVIRVPSDSVWTPDIVLFDNADGRFEGTSTKTVIRYNGTVTWTPPANYKSS 169
Query: 481 ISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFV-----IDKRIYSMFESGAW 618
++ + +P D+Q C+ KFGS ++ ++D + +DKR F++G W
Sbjct: 170 CTIDVTFFPFDLQNCSMKFGSWTYDGSQVDIILEDQDVDKR--DFFDNGEW 218
>U62434-1|AAB40112.1| 468|Homo sapiens nicotinic acetylcholine
receptor alpha5 subunit precursor protein.
Length = 468
Score = 65.7 bits (153), Expect = 2e-10
Identities = 42/171 (24%), Positives = 80/171 (46%), Gaps = 11/171 (6%)
Frame = +1
Query: 139 MIDSLLATYDRESPP----DSKIVVNLTLHLRH-ANIRESESTVRILADLQMNWIDKRLS 303
++ L Y+R P + KI + L + ++ E + L+ WID +L
Sbjct: 50 LLKDLFQDYERWVRPVEHLNDKIKIKFGLAISQLVDVDEKNQLMTTNVWLKQEWIDVKLR 109
Query: 304 WNAGEWG-CSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVSXIKRLDISTP 480
WN ++G V S+ +W PD+VL + A + + + NG+V+ + +
Sbjct: 110 WNPDDYGGIKVIRVPSDSVWTPDIVLFDNADGRFEGTSTKTVIRYNGTVTWTPPANYKSS 169
Query: 481 ISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFV-----IDKRIYSMFESGAW 618
++ + +P D+Q C+ KFGS ++ ++D + +DKR F++G W
Sbjct: 170 CTIDVTFFPFDLQNCSMKFGSWTYDGSQVDIILEDQDVDKR--DFFDNGEW 218
>BC033639-1|AAH33639.1| 468|Homo sapiens cholinergic receptor,
nicotinic, alpha 5 protein.
Length = 468
Score = 65.7 bits (153), Expect = 2e-10
Identities = 42/171 (24%), Positives = 80/171 (46%), Gaps = 11/171 (6%)
Frame = +1
Query: 139 MIDSLLATYDRESPP----DSKIVVNLTLHLRH-ANIRESESTVRILADLQMNWIDKRLS 303
++ L Y+R P + KI + L + ++ E + L+ WID +L
Sbjct: 50 LLKDLFQDYERWVRPVEHLNDKIKIKFGLAISQLVDVDEKNQLMTTNVWLKQEWIDVKLR 109
Query: 304 WNAGEWG-CSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVSXIKRLDISTP 480
WN ++G V S+ +W PD+VL + A + + + NG+V+ + +
Sbjct: 110 WNPDDYGGIKVIRVPSDSVWTPDIVLFDNADGRFEGTSTKTVIRYNGTVTWTPPANYKSS 169
Query: 481 ISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFV-----IDKRIYSMFESGAW 618
++ + +P D+Q C+ KFGS ++ ++D + +DKR F++G W
Sbjct: 170 CTIDVTFFPFDLQNCSMKFGSWTYDGSQVDIILEDQDVDKR--DFFDNGEW 218
>AJ306481-1|CAC34820.1| 468|Homo sapiens neuronal nicotinic
acetylcholine receptor alpha-5subunit protein.
Length = 468
Score = 65.7 bits (153), Expect = 2e-10
Identities = 42/171 (24%), Positives = 80/171 (46%), Gaps = 11/171 (6%)
Frame = +1
Query: 139 MIDSLLATYDRESPP----DSKIVVNLTLHLRH-ANIRESESTVRILADLQMNWIDKRLS 303
++ L Y+R P + KI + L + ++ E + L+ WID +L
Sbjct: 50 LLKDLFQDYERWVRPVEHLNDKIKIKFGLAISQLVDVDEKNQLMTTNVWLKQEWIDVKLR 109
Query: 304 WNAGEWG-CSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVSXIKRLDISTP 480
WN ++G V S+ +W PD+VL + A + + + NG+V+ + +
Sbjct: 110 WNPDDYGGIKVIRVPSDSVWTPDIVLFDNADGRFEGTSTKTVIRYNGTVTWTPPANYKSS 169
Query: 481 ISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFV-----IDKRIYSMFESGAW 618
++ + +P D+Q C+ KFGS ++ ++D + +DKR F++G W
Sbjct: 170 CTIDVTFFPFDLQNCSMKFGSWTYDGSQVDIILEDQDVDKR--DFFDNGEW 218
>X53559-1|CAA37625.1| 474|Homo sapiens neuronal nicotinic
acetylcholine receptor alpha-3merase protein.
Length = 474
Score = 65.3 bits (152), Expect = 3e-10
Identities = 35/121 (28%), Positives = 62/121 (51%), Gaps = 5/121 (4%)
Frame = +1
Query: 271 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 444
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 56 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 115
Query: 445 VSXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVI---DKRIYSMFESGA 615
V+ I + + + +P D Q CT KFGS ++ ++D V+ + +ESG
Sbjct: 116 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVLIGSSMNLKDYWESGE 175
Query: 616 W 618
W
Sbjct: 176 W 176
>Y08417-1|CAA69694.1| 458|Homo sapiens nicotinic acetylcholine
receptor beta3 subunit precursor protein.
Length = 458
Score = 64.9 bits (151), Expect = 4e-10
Identities = 37/121 (30%), Positives = 60/121 (49%), Gaps = 5/121 (4%)
Frame = +1
Query: 271 LQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLL-NAAATTAGDYALRARVSNNGS 444
L+ W D +L WN ++G + V SE LW PD+VL NA G + V +NG+
Sbjct: 81 LKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFEGSLMTKVIVKSNGT 140
Query: 445 VSXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFV-IDKRI--YSMFESGA 615
V + +M + +P D Q C+ KFGS ++ +D + I++ + F++G
Sbjct: 141 VVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGTMVDLILINENVDRKDFFDNGE 200
Query: 616 W 618
W
Sbjct: 201 W 201
>X67513-1|CAA47851.1| 423|Homo sapiens nicotinic acetylcholine
receptor beta-3 subunit protein.
Length = 423
Score = 64.9 bits (151), Expect = 4e-10
Identities = 37/121 (30%), Positives = 60/121 (49%), Gaps = 5/121 (4%)
Frame = +1
Query: 271 LQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLL-NAAATTAGDYALRARVSNNGS 444
L+ W D +L WN ++G + V SE LW PD+VL NA G + V +NG+
Sbjct: 46 LKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFEGSLMTKVIVKSNGT 105
Query: 445 VSXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFV-IDKRI--YSMFESGA 615
V + +M + +P D Q C+ KFGS ++ +D + I++ + F++G
Sbjct: 106 VVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGTMVDLILINENVDRKDFFDNGE 165
Query: 616 W 618
W
Sbjct: 166 W 166
>U62438-1|AAB40116.1| 458|Homo sapiens nicotinic acetylcholine
receptor beta3 subunit precursor protein.
Length = 458
Score = 64.9 bits (151), Expect = 4e-10
Identities = 37/121 (30%), Positives = 60/121 (49%), Gaps = 5/121 (4%)
Frame = +1
Query: 271 LQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLL-NAAATTAGDYALRARVSNNGS 444
L+ W D +L WN ++G + V SE LW PD+VL NA G + V +NG+
Sbjct: 81 LKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFEGSLMTKVIVKSNGT 140
Query: 445 VSXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFV-IDKRI--YSMFESGA 615
V + +M + +P D Q C+ KFGS ++ +D + I++ + F++G
Sbjct: 141 VVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGTMVDLILINENVDRKDFFDNGE 200
Query: 616 W 618
W
Sbjct: 201 W 201
>BC069788-1|AAH69788.1| 458|Homo sapiens cholinergic receptor,
nicotinic, beta 3 protein.
Length = 458
Score = 64.9 bits (151), Expect = 4e-10
Identities = 37/121 (30%), Positives = 60/121 (49%), Gaps = 5/121 (4%)
Frame = +1
Query: 271 LQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLL-NAAATTAGDYALRARVSNNGS 444
L+ W D +L WN ++G + V SE LW PD+VL NA G + V +NG+
Sbjct: 81 LKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFEGSLMTKVIVKSNGT 140
Query: 445 VSXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFV-IDKRI--YSMFESGA 615
V + +M + +P D Q C+ KFGS ++ +D + I++ + F++G
Sbjct: 141 VVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGTMVDLILINENVDRKDFFDNGE 200
Query: 616 W 618
W
Sbjct: 201 W 201
>BC069703-1|AAH69703.1| 458|Homo sapiens cholinergic receptor,
nicotinic, beta 3 protein.
Length = 458
Score = 64.9 bits (151), Expect = 4e-10
Identities = 37/121 (30%), Positives = 60/121 (49%), Gaps = 5/121 (4%)
Frame = +1
Query: 271 LQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLL-NAAATTAGDYALRARVSNNGS 444
L+ W D +L WN ++G + V SE LW PD+VL NA G + V +NG+
Sbjct: 81 LKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFEGSLMTKVIVKSNGT 140
Query: 445 VSXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFV-IDKRI--YSMFESGA 615
V + +M + +P D Q C+ KFGS ++ +D + I++ + F++G
Sbjct: 141 VVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGTMVDLILINENVDRKDFFDNGE 200
Query: 616 W 618
W
Sbjct: 201 W 201
>BC069681-1|AAH69681.1| 458|Homo sapiens cholinergic receptor,
nicotinic, beta 3 protein.
Length = 458
Score = 64.9 bits (151), Expect = 4e-10
Identities = 37/121 (30%), Positives = 60/121 (49%), Gaps = 5/121 (4%)
Frame = +1
Query: 271 LQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLL-NAAATTAGDYALRARVSNNGS 444
L+ W D +L WN ++G + V SE LW PD+VL NA G + V +NG+
Sbjct: 81 LKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFEGSLMTKVIVKSNGT 140
Query: 445 VSXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFV-IDKRI--YSMFESGA 615
V + +M + +P D Q C+ KFGS ++ +D + I++ + F++G
Sbjct: 141 VVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGTMVDLILINENVDRKDFFDNGE 200
Query: 616 W 618
W
Sbjct: 201 W 201
>AF140765-1|AAD33063.1| 458|Homo sapiens neuronal acetylcholine
receptor beta-3 subunit precursor protein.
Length = 458
Score = 64.9 bits (151), Expect = 4e-10
Identities = 37/121 (30%), Positives = 60/121 (49%), Gaps = 5/121 (4%)
Frame = +1
Query: 271 LQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLL-NAAATTAGDYALRARVSNNGS 444
L+ W D +L WN ++G + V SE LW PD+VL NA G + V +NG+
Sbjct: 81 LKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFEGSLMTKVIVKSNGT 140
Query: 445 VSXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFV-IDKRI--YSMFESGA 615
V + +M + +P D Q C+ KFGS ++ +D + I++ + F++G
Sbjct: 141 VVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGTMVDLILINENVDRKDFFDNGE 200
Query: 616 W 618
W
Sbjct: 201 W 201
>X68275-1|CAA48336.1| 451|Homo sapiens nicotinic receptor beta 4
subunit protein.
Length = 451
Score = 64.5 bits (150), Expect = 5e-10
Identities = 43/148 (29%), Positives = 70/148 (47%), Gaps = 6/148 (4%)
Frame = +1
Query: 193 IVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 366
I + L L L ++ E + + L+ W D RL+WN+ + G + + ++R+W P
Sbjct: 7 ISIKLQLSLAQLISVNERDEIMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLP 66
Query: 367 DVVLLNAA-ATTAGDYALRARVSNNGSVSXIKRLDISTPISMQLDNWPNDMQTCTFKFGS 543
D+VL N A T V +NGSV + + +++ +P D Q CT KF S
Sbjct: 67 DIVLYNNADGTYEVSVYTNLIVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRS 126
Query: 544 RMHNSDEMDFVIDKRIYSMFE---SGAW 618
++ E+D V+ SM + SG W
Sbjct: 127 WTYDHTEIDMVLMTPTASMDDFTPSGEW 154
>M83712-1|AAA58357.1| 468|Homo sapiens nicotinic receptor alpha 5
subunit protein.
Length = 468
Score = 64.5 bits (150), Expect = 5e-10
Identities = 42/171 (24%), Positives = 79/171 (46%), Gaps = 11/171 (6%)
Frame = +1
Query: 139 MIDSLLATYDRESPP----DSKIVVNLTLHLRH-ANIRESESTVRILADLQMNWIDKRLS 303
++ L Y+R P + KI + L + ++ E + L+ WID +L
Sbjct: 50 LLKDLFQDYERWVRPVEHLNDKIKIKFGLAISQLVDVDEKNQLMTTNVWLKQEWIDVKLR 109
Query: 304 WNAGEWG-CSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVSXIKRLDISTP 480
WN ++G V S+ W PD+VL + A + + + NG+V+ + +
Sbjct: 110 WNPDDYGGIKVIRVPSDSSWTPDIVLFDNADGRFEGTSTKTVIRYNGTVTWTPPANYKSS 169
Query: 481 ISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFV-----IDKRIYSMFESGAW 618
++ + +P D+Q C+ KFGS ++ ++D + +DKR F++G W
Sbjct: 170 CTIDVTFFPFDLQNCSMKFGSWTYDGSQVDIILEDQDVDKR--DFFDNGEW 218
>M86383-1|AAC84176.1| 502|Homo sapiens nicotinic acetylcholine
receptor alpha 3 subunit precursor protein.
Length = 502
Score = 63.7 bits (148), Expect = 8e-10
Identities = 49/195 (25%), Positives = 90/195 (46%), Gaps = 9/195 (4%)
Frame = +1
Query: 61 IILLPFLLTCAIASAAECENATSLSLMIDSLLATYDRESPPDSKIVVNLTLHLRH-ANIR 237
++LL LL A AS AE L + ++ S P ++++ + + +
Sbjct: 16 LLLLLSLLPVARASEAEHRLFERLFEDYNEIIRPVANVSDP---VIIHFEVSMSQLVKVD 72
Query: 238 ESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYA 414
E + L+ W D +L WN +G + ++ V ++++W+PD+VL N A GD+
Sbjct: 73 EVNQIMETNLWLKQIWNDYKLKWNPSGYGGAEFMRVPAQKIWKPDIVLYNNAV---GDFQ 129
Query: 415 L----RARVSNNGSVSXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVI- 579
+ +A + G V+ I + + + +P D Q CT KFGS ++ ++D V+
Sbjct: 130 VTTKTKALLKYTGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVLI 189
Query: 580 --DKRIYSMFESGAW 618
+ +ESG W
Sbjct: 190 GSSMNLKDYWESGEW 204
>Y16281-1|CAA76154.1| 529|Homo sapiens nicotinic acetylcholine
receptor alpha2 subunit precursor protein.
Length = 529
Score = 62.9 bits (146), Expect = 1e-09
Identities = 39/123 (31%), Positives = 63/123 (51%), Gaps = 7/123 (5%)
Frame = +1
Query: 271 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAA-ATTAGDYALRARVSNNGS 444
L+ W D +L WN ++G T L V SE +W PD+VL N A A + +A + + G+
Sbjct: 111 LKQEWSDYKLRWNPADFGNITSLRVPSEMIWIPDIVLYNNADGEFAVTHMTKAHLFSTGT 170
Query: 445 VSXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNS-----DEMDFVIDKRIYSMFES 609
V + + S+ + +P D Q C KFGS ++ ++M+ +D + Y +ES
Sbjct: 171 VHWVPPAIYKSSCSIDVTFFPFDQQNCKMKFGSWTYDKAKIDLEQMEQTVDLKDY--WES 228
Query: 610 GAW 618
G W
Sbjct: 229 GEW 231
>U62431-1|AAB40109.1| 529|Homo sapiens nicotinic acetylcholine
receptor alpha2 subunit precursor protein.
Length = 529
Score = 62.9 bits (146), Expect = 1e-09
Identities = 39/123 (31%), Positives = 63/123 (51%), Gaps = 7/123 (5%)
Frame = +1
Query: 271 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAA-ATTAGDYALRARVSNNGS 444
L+ W D +L WN ++G T L V SE +W PD+VL N A A + +A + + G+
Sbjct: 111 LKQEWSDYKLRWNPADFGNITSLRVPSEMIWIPDIVLYNNADGEFAVTHMTKAHLFSTGT 170
Query: 445 VSXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNS-----DEMDFVIDKRIYSMFES 609
V + + S+ + +P D Q C KFGS ++ ++M+ +D + Y +ES
Sbjct: 171 VHWVPPAIYKSSCSIDVTFFPFDQQNCKMKFGSWTYDKAKIDLEQMEQTVDLKDY--WES 228
Query: 610 GAW 618
G W
Sbjct: 229 GEW 231
>Y08421-1|CAA69698.1| 627|Homo sapiens nicotinic acetylcholine
receptor alpha4 subunit precursor protein.
Length = 627
Score = 62.1 bits (144), Expect = 3e-09
Identities = 53/198 (26%), Positives = 98/198 (49%), Gaps = 14/198 (7%)
Frame = +1
Query: 67 LLPFLLTCAIASAAECEN-ATSLSLMIDSLLATYDRESPPDSKI--VVNLTLHLRHANIR 237
LL L T + +++ E A + ++ L + Y++ S P + I VV + L A +
Sbjct: 15 LLLLLGTGLLRASSHVETRAHAEERLLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLI 74
Query: 238 ESESTVRILAD---LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAG 405
+ + +++ ++ W D +L W+ ++ T + + SE +WRPD+VL N A G
Sbjct: 75 DVDEKNQMMTTNVWVKQEWHDYKLRWDPADYENVTSIRIPSELIWRPDIVLYNNAD---G 131
Query: 406 DYAL----RARVSNNGSVSXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDF 573
D+A+ +A + ++G V + S+ + +P D Q CT KFGS ++ ++D
Sbjct: 132 DFAVTHLTKAHLFHDGRVQWTPPAIYKSSCSIDVTFFPFDQQNCTMKFGSWTYDKAKIDL 191
Query: 574 V-IDKRI--YSMFESGAW 618
V + R+ +ESG W
Sbjct: 192 VNMHSRVDQLDFWESGEW 209
>X89741-1|CAA61893.1| 627|Homo sapiens neuronal acetylcholine
receptor alpha-4 subunit protein.
Length = 627
Score = 62.1 bits (144), Expect = 3e-09
Identities = 53/198 (26%), Positives = 98/198 (49%), Gaps = 14/198 (7%)
Frame = +1
Query: 67 LLPFLLTCAIASAAECEN-ATSLSLMIDSLLATYDRESPPDSKI--VVNLTLHLRHANIR 237
LL L T + +++ E A + ++ L + Y++ S P + I VV + L A +
Sbjct: 15 LLLLLGTGLLRASSHVETRAHAEERLLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLI 74
Query: 238 ESESTVRILAD---LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAG 405
+ + +++ ++ W D +L W+ ++ T + + SE +WRPD+VL N A G
Sbjct: 75 DVDEKNQMMTTNVWVKQEWHDYKLRWDPADYENVTSIRIPSELIWRPDIVLYNNAD---G 131
Query: 406 DYAL----RARVSNNGSVSXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDF 573
D+A+ +A + ++G V + S+ + +P D Q CT KFGS ++ ++D
Sbjct: 132 DFAVTHLTKAHLFHDGRVQWTPPAIYKSSCSIDVTFFPFDQQNCTMKFGSWTYDKAKIDL 191
Query: 574 V-IDKRI--YSMFESGAW 618
V + R+ +ESG W
Sbjct: 192 VNMHSRVDQLDFWESGEW 209
>U62433-1|AAB40111.1| 627|Homo sapiens nicotinic acetylcholine
receptor alpha4 subunit precursor protein.
Length = 627
Score = 62.1 bits (144), Expect = 3e-09
Identities = 53/198 (26%), Positives = 98/198 (49%), Gaps = 14/198 (7%)
Frame = +1
Query: 67 LLPFLLTCAIASAAECEN-ATSLSLMIDSLLATYDRESPPDSKI--VVNLTLHLRHANIR 237
LL L T + +++ E A + ++ L + Y++ S P + I VV + L A +
Sbjct: 15 LLLLLGTGLLRASSHVETRAHAEERLLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLI 74
Query: 238 ESESTVRILAD---LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAG 405
+ + +++ ++ W D +L W+ ++ T + + SE +WRPD+VL N A G
Sbjct: 75 DVDEKNQMMTTNVWVKQEWHDYKLRWDPADYENVTSIRIPSELIWRPDIVLYNNAD---G 131
Query: 406 DYAL----RARVSNNGSVSXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDF 573
D+A+ +A + ++G V + S+ + +P D Q CT KFGS ++ ++D
Sbjct: 132 DFAVTHLTKAHLFHDGRVQWTPPAIYKSSCSIDVTFFPFDQQNCTMKFGSWTYDKAKIDL 191
Query: 574 V-IDKRI--YSMFESGAW 618
V + R+ +ESG W
Sbjct: 192 VNMHSRVDQLDFWESGEW 209
>L35901-1|AAA64743.1| 627|Homo sapiens nicotinic acetylcholine
receptor alpha 4 subunit protein.
Length = 627
Score = 62.1 bits (144), Expect = 3e-09
Identities = 53/198 (26%), Positives = 98/198 (49%), Gaps = 14/198 (7%)
Frame = +1
Query: 67 LLPFLLTCAIASAAECEN-ATSLSLMIDSLLATYDRESPPDSKI--VVNLTLHLRHANIR 237
LL L T + +++ E A + ++ L + Y++ S P + I VV + L A +
Sbjct: 15 LLLLLGTGLLRASSHVETRAHAEERLLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLI 74
Query: 238 ESESTVRILAD---LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAG 405
+ + +++ ++ W D +L W+ ++ T + + SE +WRPD+VL N A G
Sbjct: 75 DVDEKNQMMTTNVWVKQEWHDYKLRWDPADYENVTSIRIPSELIWRPDIVLYNNAD---G 131
Query: 406 DYAL----RARVSNNGSVSXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDF 573
D+A+ +A + ++G V + S+ + +P D Q CT KFGS ++ ++D
Sbjct: 132 DFAVTHLTKAHLFHDGRVQWTPPAIYKSSCSIDVTFFPFDQQNCTMKFGSWTYDKAKIDL 191
Query: 574 V-IDKRI--YSMFESGAW 618
V + R+ +ESG W
Sbjct: 192 VNMHSRVDQLDFWESGEW 209
>DQ093071-1|AAY88737.1| 627|Homo sapiens cholinergic receptor,
nicotinic, alpha polypeptide 4 protein.
Length = 627
Score = 62.1 bits (144), Expect = 3e-09
Identities = 53/198 (26%), Positives = 98/198 (49%), Gaps = 14/198 (7%)
Frame = +1
Query: 67 LLPFLLTCAIASAAECEN-ATSLSLMIDSLLATYDRESPPDSKI--VVNLTLHLRHANIR 237
LL L T + +++ E A + ++ L + Y++ S P + I VV + L A +
Sbjct: 15 LLLLLGTGLLRASSHVETRAHAEERLLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLI 74
Query: 238 ESESTVRILAD---LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAG 405
+ + +++ ++ W D +L W+ ++ T + + SE +WRPD+VL N A G
Sbjct: 75 DVDEKNQMMTTNVWVKQEWHDYKLRWDPADYENVTSIRIPSELIWRPDIVLYNNAD---G 131
Query: 406 DYAL----RARVSNNGSVSXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDF 573
D+A+ +A + ++G V + S+ + +P D Q CT KFGS ++ ++D
Sbjct: 132 DFAVTHLTKAHLFHDGRVQWTPPAIYKSSCSIDVTFFPFDQQNCTMKFGSWTYDKAKIDL 191
Query: 574 V-IDKRI--YSMFESGAW 618
V + R+ +ESG W
Sbjct: 192 VNMHSRVDQLDFWESGEW 209
>BC096290-1|AAH96290.1| 627|Homo sapiens cholinergic receptor,
nicotinic, alpha 4 protein.
Length = 627
Score = 62.1 bits (144), Expect = 3e-09
Identities = 53/198 (26%), Positives = 98/198 (49%), Gaps = 14/198 (7%)
Frame = +1
Query: 67 LLPFLLTCAIASAAECEN-ATSLSLMIDSLLATYDRESPPDSKI--VVNLTLHLRHANIR 237
LL L T + +++ E A + ++ L + Y++ S P + I VV + L A +
Sbjct: 15 LLLLLGTGLLRASSHVETRAHAEERLLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLI 74
Query: 238 ESESTVRILAD---LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAG 405
+ + +++ ++ W D +L W+ ++ T + + SE +WRPD+VL N A G
Sbjct: 75 DVDEKNQMMTTNVWVKQEWHDYKLRWDPADYENVTSIRIPSELIWRPDIVLYNNAD---G 131
Query: 406 DYAL----RARVSNNGSVSXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDF 573
D+A+ +A + ++G V + S+ + +P D Q CT KFGS ++ ++D
Sbjct: 132 DFAVTHLTKAHLFHDGRVQWTPPAIYKSSCSIDVTFFPFDQQNCTMKFGSWTYDKAKIDL 191
Query: 574 V-IDKRI--YSMFESGAW 618
V + R+ +ESG W
Sbjct: 192 VNMHSRVDQLDFWESGEW 209
>X87629-1|CAA60959.1| 602|Homo sapiens nicotinic acetylcholine
receptor protein.
Length = 602
Score = 61.7 bits (143), Expect = 3e-09
Identities = 47/173 (27%), Positives = 87/173 (50%), Gaps = 13/173 (7%)
Frame = +1
Query: 139 MIDSLLATYDRESPPDSKI--VVNLTLHLRHANIRESESTVRILAD---LQMNWIDKRLS 303
++ L + Y++ S P + I VV + L A + + + +++ ++ W D +L
Sbjct: 15 LLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLR 74
Query: 304 WNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNGSVSXIKRLD 468
W+ ++ T + + SE +WRPD+VL N A GD+A+ +A + ++G V
Sbjct: 75 WDPADYENVTSIRIPSELIWRPDIVLYNNAD---GDFAVTHLTKAHLFHDGRVQWTPPAI 131
Query: 469 ISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFV-IDKRI--YSMFESGAW 618
+ S+ + +P D Q CT KFGS ++ ++D V + R+ +ESG W
Sbjct: 132 YKSSCSIDVTFFPFDQQNCTMKFGSWTYDKAKIDLVNMHSRVDQLDFWESGEW 184
>Y16282-1|CAA76155.1| 494|Homo sapiens nicotinic acetylcholine
receptor alpha6 subunit precursor protein.
Length = 494
Score = 60.9 bits (141), Expect = 6e-09
Identities = 42/166 (25%), Positives = 77/166 (46%), Gaps = 10/166 (6%)
Frame = +1
Query: 112 CENATSLSLMIDSLLATYDRESPPDSKIVVNLTLHL-----RHANIRESESTVRILADLQ 276
C + + L + Y++ P + +T+H + AN+ E + L+
Sbjct: 28 CVGCATEERLFHKLFSHYNQFIRPVENVSDPVTVHFEVAITQLANVDEVNQIMETNLWLR 87
Query: 277 MNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNG 441
W D +L W+ E+ G T V ++++W+PD+VL N A GD+ + +A + NG
Sbjct: 88 HIWNDYKLRWDPMEYDGIETLRVPADKIWKPDIVLYNNAV---GDFQVEGKTKALLKYNG 144
Query: 442 SVSXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVI 579
++ + M + +P D Q C+ KFGS ++ E+D +I
Sbjct: 145 MITWTPPAIFKSSCPMDITFFPFDHQNCSLKFGSWTYDKAEIDLLI 190
>U62435-1|AAB40113.1| 494|Homo sapiens nicotinic acetylcholine
receptor alpha6 subunit precursor protein.
Length = 494
Score = 60.9 bits (141), Expect = 6e-09
Identities = 42/166 (25%), Positives = 77/166 (46%), Gaps = 10/166 (6%)
Frame = +1
Query: 112 CENATSLSLMIDSLLATYDRESPPDSKIVVNLTLHL-----RHANIRESESTVRILADLQ 276
C + + L + Y++ P + +T+H + AN+ E + L+
Sbjct: 28 CVGCATEERLFHKLFSHYNQFIRPVENVSDPVTVHFEVAITQLANVDEVNQIMETNLWLR 87
Query: 277 MNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNG 441
W D +L W+ E+ G T V ++++W+PD+VL N A GD+ + +A + NG
Sbjct: 88 HIWNDYKLRWDPMEYDGIETLRVPADKIWKPDIVLYNNAV---GDFQVEGKTKALLKYNG 144
Query: 442 SVSXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVI 579
++ + M + +P D Q C+ KFGS ++ E+D +I
Sbjct: 145 MITWTPPAIFKSSCPMDITFFPFDHQNCSLKFGSWTYDKAEIDLLI 190
>BC014456-1|AAH14456.1| 494|Homo sapiens cholinergic receptor,
nicotinic, alpha 6 protein.
Length = 494
Score = 60.9 bits (141), Expect = 6e-09
Identities = 42/166 (25%), Positives = 77/166 (46%), Gaps = 10/166 (6%)
Frame = +1
Query: 112 CENATSLSLMIDSLLATYDRESPPDSKIVVNLTLHL-----RHANIRESESTVRILADLQ 276
C + + L + Y++ P + +T+H + AN+ E + L+
Sbjct: 28 CVGCATEERLFHKLFSHYNQFIRPVENVSDPVTVHFEVAITQLANVDEVNQIMETNLWLR 87
Query: 277 MNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNG 441
W D +L W+ E+ G T V ++++W+PD+VL N A GD+ + +A + NG
Sbjct: 88 HIWNDYKLRWDPMEYDGIETLRVPADKIWKPDIVLYNNAV---GDFQVEGKTKALLKYNG 144
Query: 442 SVSXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVI 579
++ + M + +P D Q C+ KFGS ++ E+D +I
Sbjct: 145 MITWTPPAIFKSSCPMDITFFPFDHQNCSLKFGSWTYDKAEIDLLI 190
>AB079251-1|BAC06855.1| 494|Homo sapiens Nicotinic acetylcholine
receptor alpha 6 protein.
Length = 494
Score = 60.9 bits (141), Expect = 6e-09
Identities = 42/166 (25%), Positives = 77/166 (46%), Gaps = 10/166 (6%)
Frame = +1
Query: 112 CENATSLSLMIDSLLATYDRESPPDSKIVVNLTLHL-----RHANIRESESTVRILADLQ 276
C + + L + Y++ P + +T+H + AN+ E + L+
Sbjct: 28 CVGCATEERLFHKLFSHYNQFIRPVENVSDPVTVHFEVAITQLANVDEVNQIMETNLWLR 87
Query: 277 MNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNG 441
W D +L W+ E+ G T V ++++W+PD+VL N A GD+ + +A + NG
Sbjct: 88 HIWNDYKLRWDPMEYDGIETLRVPADKIWKPDIVLYNNAV---GDFQVEGKTKALLKYNG 144
Query: 442 SVSXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVI 579
++ + M + +P D Q C+ KFGS ++ E+D +I
Sbjct: 145 MITWTPPAIFKSSCPMDITFFPFDHQNCSLKFGSWTYDKAEIDLLI 190
>X14830-1|CAA32939.1| 501|Homo sapiens protein ( Human mRNA for
muscle acetylcholine receptor beta-subunit. ).
Length = 501
Score = 60.1 bits (139), Expect = 1e-08
Identities = 46/137 (33%), Positives = 69/137 (50%), Gaps = 4/137 (2%)
Frame = +1
Query: 169 RESPPDSKIVVNLTL-HLRHANIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLV 342
RE ++ V L L L N ++ E + ++ DL+ W D RLSW+ E G + +
Sbjct: 46 REVGDRVRVSVGLILAQLISLNEKDEEMSTKVYLDLE--WTDYRLSWDPAEHDGIDSLRI 103
Query: 343 SSERLWRPDVVLLNAAATTAGDYAL--RARVSNNGSVSXIKRLDISTPISMQLDNWPNDM 516
++E +W PDVVLLN D AL VS++GSV + S+Q+ +P D
Sbjct: 104 TAESVWLPDVVLLNNNDGNF-DVALDISVVVSSDGSVRWQPPGIYRSSCSIQVTYFPFDW 162
Query: 517 QTCTFKFGSRMHNSDEM 567
Q CT F S ++S E+
Sbjct: 163 QNCTMVFSSYSYDSSEV 179
>BC011371-1|AAH11371.1| 501|Homo sapiens cholinergic receptor,
nicotinic, beta 1 (muscle) protein.
Length = 501
Score = 60.1 bits (139), Expect = 1e-08
Identities = 46/137 (33%), Positives = 69/137 (50%), Gaps = 4/137 (2%)
Frame = +1
Query: 169 RESPPDSKIVVNLTL-HLRHANIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLV 342
RE ++ V L L L N ++ E + ++ DL+ W D RLSW+ E G + +
Sbjct: 46 REVGDRVRVSVGLILAQLISLNEKDEEMSTKVYLDLE--WTDYRLSWDPAEHDGIDSLRI 103
Query: 343 SSERLWRPDVVLLNAAATTAGDYAL--RARVSNNGSVSXIKRLDISTPISMQLDNWPNDM 516
++E +W PDVVLLN D AL VS++GSV + S+Q+ +P D
Sbjct: 104 TAESVWLPDVVLLNNNDGNF-DVALDISVVVSSDGSVRWQPPGIYRSSCSIQVTYFPFDW 162
Query: 517 QTCTFKFGSRMHNSDEM 567
Q CT F S ++S E+
Sbjct: 163 QNCTMVFSSYSYDSSEV 179
>AJ001935-1|CAA05108.1| 504|Homo sapiens CHRNB2 protein.
Length = 504
Score = 60.1 bits (139), Expect = 1e-08
Identities = 53/194 (27%), Positives = 86/194 (44%), Gaps = 9/194 (4%)
Frame = +1
Query: 64 ILLPF--LLTCAIASAAECENATSLSLMIDSLLATYDRESPPDSKIV-VNLTLHLRHA-N 231
+LL F L C+ A+ E L+ S R + S++V V L + L +
Sbjct: 10 LLLGFGLLRLCSGVWGADTEERLVEHLLDPSRYNKLIRPATNGSELVTVQLMVSLAQLIS 69
Query: 232 IRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAG 405
+ E E + L W D RL+W E+ + S+ +W PDVVL N A
Sbjct: 70 VHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLPDVVLYNNADGMYEV 129
Query: 406 DYALRARVSNNGSVSXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDK 585
+ A VS +GS+ + + +++ ++P D Q CT KF S ++ E+D V+
Sbjct: 130 SFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRSWTYDRTEIDLVLKS 189
Query: 586 RIYSMFE---SGAW 618
+ S+ + SG W
Sbjct: 190 EVASLDDFTPSGEW 203
>Y08415-1|CAA69692.1| 502|Homo sapiens nicotinic acetylcholine
receptor beta2 subunit precursor protein.
Length = 502
Score = 59.7 bits (138), Expect = 1e-08
Identities = 41/148 (27%), Positives = 68/148 (45%), Gaps = 6/148 (4%)
Frame = +1
Query: 193 IVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 366
+ V L + L ++ E E + L W D RL+W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 367 DVVLLNAA-ATTAGDYALRARVSNNGSVSXIKRLDISTPISMQLDNWPNDMQTCTFKFGS 543
DVVL N A + A VS +GS+ + + +++ ++P D Q CT KF S
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRS 175
Query: 544 RMHNSDEMDFVIDKRIYSMFE---SGAW 618
++ E+D V+ + S+ + SG W
Sbjct: 176 WTYDRTEIDLVLKSEVASLDDFTPSGEW 203
>X53179-1|CAA37320.1| 502|Homo sapiens precursor peptide (AA -25 to
477) protein.
Length = 502
Score = 59.7 bits (138), Expect = 1e-08
Identities = 41/148 (27%), Positives = 68/148 (45%), Gaps = 6/148 (4%)
Frame = +1
Query: 193 IVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 366
+ V L + L ++ E E + L W D RL+W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 367 DVVLLNAA-ATTAGDYALRARVSNNGSVSXIKRLDISTPISMQLDNWPNDMQTCTFKFGS 543
DVVL N A + A VS +GS+ + + +++ ++P D Q CT KF S
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRS 175
Query: 544 RMHNSDEMDFVIDKRIYSMFE---SGAW 618
++ E+D V+ + S+ + SG W
Sbjct: 176 WTYDRTEIDLVLKSEVASLDDFTPSGEW 203
>U62437-1|AAB40115.1| 502|Homo sapiens nicotinic acetylcholine
receptor beta2 subunit precursor protein.
Length = 502
Score = 59.7 bits (138), Expect = 1e-08
Identities = 41/148 (27%), Positives = 68/148 (45%), Gaps = 6/148 (4%)
Frame = +1
Query: 193 IVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 366
+ V L + L ++ E E + L W D RL+W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 367 DVVLLNAA-ATTAGDYALRARVSNNGSVSXIKRLDISTPISMQLDNWPNDMQTCTFKFGS 543
DVVL N A + A VS +GS+ + + +++ ++P D Q CT KF S
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRS 175
Query: 544 RMHNSDEMDFVIDKRIYSMFE---SGAW 618
++ E+D V+ + S+ + SG W
Sbjct: 176 WTYDRTEIDLVLKSEVASLDDFTPSGEW 203
>BC075041-1|AAH75041.1| 502|Homo sapiens cholinergic receptor,
nicotinic, beta 2 (neuronal) protein.
Length = 502
Score = 59.7 bits (138), Expect = 1e-08
Identities = 41/148 (27%), Positives = 68/148 (45%), Gaps = 6/148 (4%)
Frame = +1
Query: 193 IVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 366
+ V L + L ++ E E + L W D RL+W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 367 DVVLLNAA-ATTAGDYALRARVSNNGSVSXIKRLDISTPISMQLDNWPNDMQTCTFKFGS 543
DVVL N A + A VS +GS+ + + +++ ++P D Q CT KF S
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRS 175
Query: 544 RMHNSDEMDFVIDKRIYSMFE---SGAW 618
++ E+D V+ + S+ + SG W
Sbjct: 176 WTYDRTEIDLVLKSEVASLDDFTPSGEW 203
>BC075040-1|AAH75040.1| 502|Homo sapiens cholinergic receptor,
nicotinic, beta 2 (neuronal) protein.
Length = 502
Score = 59.7 bits (138), Expect = 1e-08
Identities = 41/148 (27%), Positives = 68/148 (45%), Gaps = 6/148 (4%)
Frame = +1
Query: 193 IVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 366
+ V L + L ++ E E + L W D RL+W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 367 DVVLLNAA-ATTAGDYALRARVSNNGSVSXIKRLDISTPISMQLDNWPNDMQTCTFKFGS 543
DVVL N A + A VS +GS+ + + +++ ++P D Q CT KF S
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRS 175
Query: 544 RMHNSDEMDFVIDKRIYSMFE---SGAW 618
++ E+D V+ + S+ + SG W
Sbjct: 176 WTYDRTEIDLVLKSEVASLDDFTPSGEW 203
>AL592078-3|CAI16184.1| 502|Homo sapiens cholinergic receptor,
nicotinic, beta 2 (neuronal) protein.
Length = 502
Score = 59.7 bits (138), Expect = 1e-08
Identities = 41/148 (27%), Positives = 68/148 (45%), Gaps = 6/148 (4%)
Frame = +1
Query: 193 IVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 366
+ V L + L ++ E E + L W D RL+W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 367 DVVLLNAA-ATTAGDYALRARVSNNGSVSXIKRLDISTPISMQLDNWPNDMQTCTFKFGS 543
DVVL N A + A VS +GS+ + + +++ ++P D Q CT KF S
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRS 175
Query: 544 RMHNSDEMDFVIDKRIYSMFE---SGAW 618
++ E+D V+ + S+ + SG W
Sbjct: 176 WTYDRTEIDLVLKSEVASLDDFTPSGEW 203
>AF077186-1|AAD45422.1| 502|Homo sapiens neuronal nicotinic
acetylcholine receptor beta 2 protein.
Length = 502
Score = 59.7 bits (138), Expect = 1e-08
Identities = 41/148 (27%), Positives = 68/148 (45%), Gaps = 6/148 (4%)
Frame = +1
Query: 193 IVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 366
+ V L + L ++ E E + L W D RL+W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 367 DVVLLNAA-ATTAGDYALRARVSNNGSVSXIKRLDISTPISMQLDNWPNDMQTCTFKFGS 543
DVVL N A + A VS +GS+ + + +++ ++P D Q CT KF S
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRS 175
Query: 544 RMHNSDEMDFVIDKRIYSMFE---SGAW 618
++ E+D V+ + S+ + SG W
Sbjct: 176 WTYDRTEIDLVLKSEVASLDDFTPSGEW 203
>DQ644022-1|ABG35128.1| 456|Homo sapiens 5-HT3 receptor subunit E
splice variant HTR3Ea protein.
Length = 456
Score = 58.8 bits (136), Expect = 2e-08
Identities = 44/198 (22%), Positives = 90/198 (45%), Gaps = 8/198 (4%)
Frame = +1
Query: 40 HKMSTTYIILLPFLLTC-AIASAAECENATSLSLMIDSLLATYDRES-PPDSKIVVNLTL 213
H+ ++ +LL FLL + C +L + ++R+ P + I V +
Sbjct: 7 HRKRFSFYLLLGFLLQGRGVTFTINCSGFGQHGADPTALNSVFNRKPFRPVTNISVPTQV 66
Query: 214 HLRHAN--IRESESTVRILAD---LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVV 375
++ A I + + +L+ L+M W + +SWN E G + ++++ LW PD+
Sbjct: 67 NISFAMSAILDVNEQLHLLSSFLWLEMVWDNPFISWNPEECEGITKMSMAAKNLWLPDIF 126
Query: 376 LLNAAATTAGDYALRARVSNNGSVSXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHN 555
++ L A VSN G + K + + + ++ + +P D Q CT F S ++
Sbjct: 127 IIELMDVDKTPKGLTAYVSNEGRIRYKKPMKVDSICNLDIFYFPFDQQNCTLTFSSFLYT 186
Query: 556 SDEMDFVIDKRIYSMFES 609
D M ++K ++ + ++
Sbjct: 187 VDSMLLDMEKEVWEITDA 204
>BC023553-1|AAH23553.1| 501|Homo sapiens cholinergic receptor,
nicotinic, beta 1 (muscle) protein.
Length = 501
Score = 58.8 bits (136), Expect = 2e-08
Identities = 44/139 (31%), Positives = 70/139 (50%), Gaps = 6/139 (4%)
Frame = +1
Query: 169 RESPPDSKIVVNLTL-HLRHANIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLV 342
RE ++ V L L L N ++ E + ++ DL+ W D RLSW+ E G + +
Sbjct: 46 REVGDRVRVSVGLILAQLISLNEKDEEMSTKVYLDLE--WTDYRLSWDPAEHDGIDSLRI 103
Query: 343 SSERLWRPDVVLLNAAATTAGDY----ALRARVSNNGSVSXIKRLDISTPISMQLDNWPN 510
++E +W PDVVLLN G++ + VS++GSV + S+Q+ +P
Sbjct: 104 TAESVWLPDVVLLN---NNDGNFYVALDISVVVSSDGSVRWQPPGIYRSSCSIQVTYFPF 160
Query: 511 DMQTCTFKFGSRMHNSDEM 567
D Q CT F S ++S E+
Sbjct: 161 DWQNCTMVFSSYSYDSSEV 179
>X66403-1|CAA47030.1| 493|Homo sapiens acetylcholine receptor
epsilon subunit CHRNE protein.
Length = 493
Score = 58.4 bits (135), Expect = 3e-08
Identities = 35/134 (26%), Positives = 70/134 (52%), Gaps = 3/134 (2%)
Frame = +1
Query: 181 PDSKIVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEWG-CSTWLVSSER 354
P+ + ++L + L + ++ E E T+ + ++W D RL+++ ++G T V SE
Sbjct: 45 PEDTVTISLKVTLTNLISLNEKEETLTTSVWIGIDWQDYRLNYSKDDFGGIETLRVPSEL 104
Query: 355 LWRPDVVLLNAAATTAG-DYALRARVSNNGSVSXIKRLDISTPISMQLDNWPNDMQTCTF 531
+W P++VL N G Y V GSV+ + + ++++ +P D Q C+
Sbjct: 105 VWLPEIVLENNIDGQFGVAYDANVLVYEGGSVTWLPPAIYRSVCAVEVTYFPFDWQNCSL 164
Query: 532 KFGSRMHNSDEMDF 573
F S+ +N++E++F
Sbjct: 165 IFRSQTYNAEEVEF 178
>BC131799-1|AAI31800.1| 447|Homo sapiens 5-hydroxytryptamine
(serotonin) receptor 3, family member C protein.
Length = 447
Score = 58.4 bits (135), Expect = 3e-08
Identities = 28/114 (24%), Positives = 58/114 (50%), Gaps = 1/114 (0%)
Frame = +1
Query: 271 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 447
+ + W + ++WN E G + V +E LW PD+ ++ + L A +S+ G +
Sbjct: 91 MDLVWDNPFINWNPKECVGINKLTVLAENLWLPDIFIVESMDVDQTPSGLTAYISSEGRI 150
Query: 448 SXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDKRIYSMFES 609
K + +++ ++ + +P D Q CTF F S ++ D M +DK ++ + ++
Sbjct: 151 KYDKPMRVTSICNLDIFYFPFDQQNCTFTFSSFLYTVDSMLLGMDKEVWEITDT 204
>BC101185-1|AAI01186.1| 374|Homo sapiens HTR3E protein protein.
Length = 374
Score = 58.4 bits (135), Expect = 3e-08
Identities = 29/114 (25%), Positives = 57/114 (50%), Gaps = 1/114 (0%)
Frame = +1
Query: 271 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 447
L+M W + +SWN E G + ++++ LW PD+ ++ L A VSN G +
Sbjct: 20 LEMVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEGRI 79
Query: 448 SXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDKRIYSMFES 609
K + + + ++ + +P D Q CT F S ++ D M ++K ++ + ++
Sbjct: 80 RYKKPMKVDSICNLDIFYFPFDQQNCTLTFSSFLYTVDSMLLDMEKEVWEITDA 133
>BC101183-1|AAI01184.1| 471|Homo sapiens 5-hydroxytryptamine
(serotonin) receptor 3, family member E protein.
Length = 471
Score = 58.4 bits (135), Expect = 3e-08
Identities = 29/114 (25%), Positives = 57/114 (50%), Gaps = 1/114 (0%)
Frame = +1
Query: 271 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 447
L+M W + +SWN E G + ++++ LW PD+ ++ L A VSN G +
Sbjct: 106 LEMVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEGRI 165
Query: 448 SXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDKRIYSMFES 609
K + + + ++ + +P D Q CT F S ++ D M ++K ++ + ++
Sbjct: 166 RYKKPMKVDSICNLDIFYFPFDQQNCTLTFSSFLYTVDSMLLDMEKEVWEITDA 219
>BC101182-1|AAI01183.1| 471|Homo sapiens 5-hydroxytryptamine
(serotonin) receptor 3, family member E protein.
Length = 471
Score = 58.4 bits (135), Expect = 3e-08
Identities = 29/114 (25%), Positives = 57/114 (50%), Gaps = 1/114 (0%)
Frame = +1
Query: 271 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 447
L+M W + +SWN E G + ++++ LW PD+ ++ L A VSN G +
Sbjct: 106 LEMVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEGRI 165
Query: 448 SXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDKRIYSMFES 609
K + + + ++ + +P D Q CT F S ++ D M ++K ++ + ++
Sbjct: 166 RYKKPMKVDSICNLDIFYFPFDQQNCTLTFSSFLYTVDSMLLDMEKEVWEITDA 219
>AY159813-1|AAO38167.2| 471|Homo sapiens 5-hydroxytryptamine
serotonin receptor 3E protein.
Length = 471
Score = 58.4 bits (135), Expect = 3e-08
Identities = 29/114 (25%), Positives = 57/114 (50%), Gaps = 1/114 (0%)
Frame = +1
Query: 271 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 447
L+M W + +SWN E G + ++++ LW PD+ ++ L A VSN G +
Sbjct: 106 LEMVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEGRI 165
Query: 448 SXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDKRIYSMFES 609
K + + + ++ + +P D Q CT F S ++ D M ++K ++ + ++
Sbjct: 166 RYKKPMKVDSICNLDIFYFPFDQQNCTLTFSSFLYTVDSMLLDMEKEVWEITDA 219
>AF105999-1|AAD24503.1| 493|Homo sapiens acetylcholine receptor
epsilon subunit protein.
Length = 493
Score = 58.4 bits (135), Expect = 3e-08
Identities = 35/134 (26%), Positives = 70/134 (52%), Gaps = 3/134 (2%)
Frame = +1
Query: 181 PDSKIVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEWG-CSTWLVSSER 354
P+ + ++L + L + ++ E E T+ + ++W D RL+++ ++G T V SE
Sbjct: 45 PEDTVTISLKVTLTNLISLNEKEETLTTSVWIGIDWQDYRLNYSKDDFGGIETLRVPSEL 104
Query: 355 LWRPDVVLLNAAATTAG-DYALRARVSNNGSVSXIKRLDISTPISMQLDNWPNDMQTCTF 531
+W P++VL N G Y V GSV+ + + ++++ +P D Q C+
Sbjct: 105 VWLPEIVLENNIDGQFGVAYDANVLVYEGGSVTWLPPAIYRSVCAVEVTYFPFDWQNCSL 164
Query: 532 KFGSRMHNSDEMDF 573
F S+ +N++E++F
Sbjct: 165 IFRSQTYNAEEVEF 178
>AF459285-1|AAL66182.1| 447|Homo sapiens 5-hydroxytryptamine
receptor 3 subunit C protein.
Length = 447
Score = 58.0 bits (134), Expect = 4e-08
Identities = 28/114 (24%), Positives = 57/114 (50%), Gaps = 1/114 (0%)
Frame = +1
Query: 271 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 447
+ + W + ++WN E G + V +E LW PD+ ++ + L A +S+ G +
Sbjct: 91 MDLVWDNPFINWNPKECVGINKLTVLAENLWLPDIFIVESMDVDQTPSGLTAYISSEGRI 150
Query: 448 SXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDKRIYSMFES 609
K + +++ + + +P D Q CTF F S ++ D M +DK ++ + ++
Sbjct: 151 KYDKPMRVTSICKLDIFYFPFDQQNCTFTFSSFLYTVDSMLLGMDKEVWEITDT 204
>Y00762-1|CAA68731.1| 457|Homo sapiens protein ( Human mRNA for
muscle acetylcholine receptor alpha-subunit. ).
Length = 457
Score = 57.6 bits (133), Expect = 5e-08
Identities = 50/195 (25%), Positives = 88/195 (45%), Gaps = 13/195 (6%)
Frame = +1
Query: 73 PFLLTCAIASAAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHA---NIR 237
P LL ++ SA + + ++ L Y P D + VV +T+ L+ N+
Sbjct: 5 PLLLLFSLCSAGLVLGSEHETRLVAKLFKDYSSVVRPVEDHRQVVEVTVGLQLIQLINVD 64
Query: 238 ESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYA 414
E V L+ W+D L WN ++G + + SE++WRPD+VL N A GD+A
Sbjct: 65 EVNQIVTTNVRLKQQWVDYNLKWNPDDYGGVKKIHIPSEKIWRPDLVLYNNA---DGDFA 121
Query: 415 L----RARVSNNGSVSXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSD--EMDFV 576
+ + + G ++ + + + ++P D Q C+ K G+ ++ ++
Sbjct: 122 IVKFTKVLLQYTGHITWTPPAIFKSYCEIIVTHFPFDEQNCSMKLGTWTYDGSVVAINPE 181
Query: 577 IDKRIYSMF-ESGAW 618
D+ S F ESG W
Sbjct: 182 SDQPDLSNFMESGEW 196
>X02502-1|CAA26344.1| 457|Homo sapiens acetylcholine receptor
protein.
Length = 457
Score = 57.6 bits (133), Expect = 5e-08
Identities = 50/195 (25%), Positives = 88/195 (45%), Gaps = 13/195 (6%)
Frame = +1
Query: 73 PFLLTCAIASAAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHA---NIR 237
P LL ++ SA + + ++ L Y P D + VV +T+ L+ N+
Sbjct: 5 PLLLLFSLCSAGLVLGSEHETRLVAKLFKDYSSVVRPVEDHRQVVEVTVGLQLIQLINVD 64
Query: 238 ESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYA 414
E V L+ W+D L WN ++G + + SE++WRPD+VL N A GD+A
Sbjct: 65 EVNQIVTTNVRLKQQWVDYNLKWNPDDYGGVKKIHIPSEKIWRPDLVLYNNA---DGDFA 121
Query: 415 L----RARVSNNGSVSXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSD--EMDFV 576
+ + + G ++ + + + ++P D Q C+ K G+ ++ ++
Sbjct: 122 IVKFTKVLLQYTGHITWTPPAIFKSYCEIIVTHFPFDEQNCSMKLGTWTYDGSVVAINPE 181
Query: 577 IDKRIYSMF-ESGAW 618
D+ S F ESG W
Sbjct: 182 SDQPDLSNFMESGEW 196
>X01715-1|CAA25861.1| 520|Homo sapiens acetylcholine receptor gamma
chain precursor protein.
Length = 520
Score = 57.6 bits (133), Expect = 5e-08
Identities = 49/183 (26%), Positives = 83/183 (45%), Gaps = 8/183 (4%)
Frame = +1
Query: 61 IILLPFLLTCAIASAAECENATSLSLMIDSLLATYDRESPPDSKI--VVNLTLHLRHANI 234
++LL L C + N L+ D L+ YD P + VVN++L L N+
Sbjct: 8 LLLLLLLAVCLGGTQRNLRNQEE-RLLAD-LMQNYDPNLRPAERDSDVVNVSLKLTLTNL 65
Query: 235 ---RESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTA 402
E E + ++M W D RL W+ ++ G V S +WRPD+VL N
Sbjct: 66 ISLNEREEALTTNVWIEMQWCDYRLRWDPRDYEGLWVLRVPSTMVWRPDIVLENNVDGVF 125
Query: 403 GDYALRARV--SNNGSVSXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFV 576
+ AL V S +G + + + S+ + +P D Q C+ F S+ ++++E+D
Sbjct: 126 -EVALYCNVLVSPDGCIYWLPPAIFRSACSISVTYFPFDWQNCSLIFQSQTYSTNEIDLQ 184
Query: 577 IDK 585
+ +
Sbjct: 185 LSQ 187
>S77094-1|AAD14247.1| 457|Homo sapiens nicotinic acetylcholine
receptor alpha subunit|AChR protein.
Length = 457
Score = 57.6 bits (133), Expect = 5e-08
Identities = 50/195 (25%), Positives = 88/195 (45%), Gaps = 13/195 (6%)
Frame = +1
Query: 73 PFLLTCAIASAAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHA---NIR 237
P LL ++ SA + + ++ L Y P D + VV +T+ L+ N+
Sbjct: 5 PLLLLFSLCSAGLVLGSEHETRLVAKLFKDYSSVVRPVEDHRQVVEVTVGLQLIQLINVD 64
Query: 238 ESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYA 414
E V L+ W+D L WN ++G + + SE++WRPD+VL N A GD+A
Sbjct: 65 EVNQIVTTNVRLKQQWVDYNLKWNPDDYGGVKKIHIPSEKIWRPDLVLYNNA---DGDFA 121
Query: 415 L----RARVSNNGSVSXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSD--EMDFV 576
+ + + G ++ + + + ++P D Q C+ K G+ ++ ++
Sbjct: 122 IVKFTKVLLQYTGHITWTPPAIFKSYCEIIVTHFPFDEQNCSMKLGTWTYDGSVVAINPE 181
Query: 577 IDKRIYSMF-ESGAW 618
D+ S F ESG W
Sbjct: 182 SDQPDLSNFMESGEW 196
>BC006314-1|AAH06314.1| 269|Homo sapiens CHRNA1 protein protein.
Length = 269
Score = 57.6 bits (133), Expect = 5e-08
Identities = 50/195 (25%), Positives = 88/195 (45%), Gaps = 13/195 (6%)
Frame = +1
Query: 73 PFLLTCAIASAAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHA---NIR 237
P LL ++ SA + + ++ L Y P D + VV +T+ L+ N+
Sbjct: 5 PLLLLFSLCSAGLVLGSEHETRLVAKLFKDYSSVVRPVEDHRQVVEVTVGLQLIQLINVD 64
Query: 238 ESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYA 414
E V L+ W+D L WN ++G + + SE++WRPD+VL N A GD+A
Sbjct: 65 EVNQIVTTNVRLKQQWVDYNLKWNPDDYGGVKKIHIPSEKIWRPDLVLYNNA---DGDFA 121
Query: 415 L----RARVSNNGSVSXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSD--EMDFV 576
+ + + G ++ + + + ++P D Q C+ K G+ ++ ++
Sbjct: 122 IVKFTKVLLQYTGHITWTPPAIFKSYCEIIVTHFPFDEQNCSMKLGTWTYDGSVVAINPE 181
Query: 577 IDKRIYSMF-ESGAW 618
D+ S F ESG W
Sbjct: 182 SDQPDLSNFMESGEW 196
>AC092165-3|AAY24103.1| 520|Homo sapiens unknown protein.
Length = 520
Score = 57.6 bits (133), Expect = 5e-08
Identities = 49/183 (26%), Positives = 83/183 (45%), Gaps = 8/183 (4%)
Frame = +1
Query: 61 IILLPFLLTCAIASAAECENATSLSLMIDSLLATYDRESPPDSKI--VVNLTLHLRHANI 234
++LL L C + N L+ D L+ YD P + VVN++L L N+
Sbjct: 8 LLLLLLLAVCLGGTQRNLRNQEE-RLLAD-LMQNYDPNLRPAERDSDVVNVSLKLTLTNL 65
Query: 235 ---RESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTA 402
E E + ++M W D RL W+ ++ G V S +WRPD+VL N
Sbjct: 66 ISLNEREEALTTNVWIEMQWCDYRLRWDPRDYEGLWVLRVPSTMVWRPDIVLENNVDGVF 125
Query: 403 GDYALRARV--SNNGSVSXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFV 576
+ AL V S +G + + + S+ + +P D Q C+ F S+ ++++E+D
Sbjct: 126 -EVALYCNVLVSPDGCIYWLPPAIFRSACSISVTYFPFDWQNCSLIFQSQTYSTNEIDLQ 184
Query: 577 IDK 585
+ +
Sbjct: 185 LSQ 187
>AC018890-1|AAY14687.1| 457|Homo sapiens unknown protein.
Length = 457
Score = 57.6 bits (133), Expect = 5e-08
Identities = 50/195 (25%), Positives = 88/195 (45%), Gaps = 13/195 (6%)
Frame = +1
Query: 73 PFLLTCAIASAAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHA---NIR 237
P LL ++ SA + + ++ L Y P D + VV +T+ L+ N+
Sbjct: 5 PLLLLFSLCSAGLVLGSEHETRLVAKLFKDYSSVVRPVEDHRQVVEVTVGLQLIQLINVD 64
Query: 238 ESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYA 414
E V L+ W+D L WN ++G + + SE++WRPD+VL N A GD+A
Sbjct: 65 EVNQIVTTNVRLKQQWVDYNLKWNPDDYGGVKKIHIPSEKIWRPDLVLYNNA---DGDFA 121
Query: 415 L----RARVSNNGSVSXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSD--EMDFV 576
+ + + G ++ + + + ++P D Q C+ K G+ ++ ++
Sbjct: 122 IVKFTKVLLQYTGHITWTPPAIFKSYCEIIVTHFPFDEQNCSMKLGTWTYDGSVVAINPE 181
Query: 577 IDKRIYSMF-ESGAW 618
D+ S F ESG W
Sbjct: 182 SDQPDLSNFMESGEW 196
>AY349353-1|AAQ93477.1| 456|Homo sapiens 5-HT3c1 serotonin
receptor-like protein protein.
Length = 456
Score = 56.4 bits (130), Expect = 1e-07
Identities = 29/116 (25%), Positives = 57/116 (49%), Gaps = 1/116 (0%)
Frame = +1
Query: 265 ADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNG 441
A L + W + +SWN E G + ++++ LW PD+ ++ L A VSN G
Sbjct: 89 AILDVVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEG 148
Query: 442 SVSXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDKRIYSMFES 609
+ K + + + ++ + +P D Q CT F S ++ D M ++K ++ + ++
Sbjct: 149 RIRYKKPMKVDSICNLDIFYFPFDQQNCTLTFSSFLYTVDSMLLDMEKEVWEITDA 204
>AY349352-1|AAQ93476.1| 441|Homo sapiens 5-HT3c1 serotonin
receptor-like protein protein.
Length = 441
Score = 56.4 bits (130), Expect = 1e-07
Identities = 29/116 (25%), Positives = 57/116 (49%), Gaps = 1/116 (0%)
Frame = +1
Query: 265 ADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNG 441
A L + W + +SWN E G + ++++ LW PD+ ++ L A VSN G
Sbjct: 74 AILDVVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEG 133
Query: 442 SVSXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDKRIYSMFES 609
+ K + + + ++ + +P D Q CT F S ++ D M ++K ++ + ++
Sbjct: 134 RIRYKKPMKVDSICNLDIFYFPFDQQNCTLTFSSFLYTVDSMLLDMEKEVWEITDA 189
>BC110597-1|AAI10598.1| 411|Homo sapiens ligand-gated ion channel,
zinc activated 1 protein.
Length = 411
Score = 54.8 bits (126), Expect = 4e-07
Identities = 28/101 (27%), Positives = 49/101 (48%)
Frame = +1
Query: 271 LQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVS 450
L+++W+D RL+WN + E LW P + +L A D + +ARV +G V
Sbjct: 86 LRLSWLDTRLAWNTSAHPRHAITLPWESLWTPRLTILEALWVDWRDQSPQARVDQDGHVK 145
Query: 451 XIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDF 573
L T + +L ++P D C+ F + + + E++F
Sbjct: 146 LNLALTTETNCNFELLHFPRDHSNCSLSFYALSNTAMELEF 186
>AJ295237-1|CAC16144.1| 450|Homo sapiens neuronal nicotinic
acetylcholine receptor subunit4 protein.
Length = 450
Score = 54.8 bits (126), Expect = 4e-07
Identities = 47/176 (26%), Positives = 76/176 (43%), Gaps = 7/176 (3%)
Frame = +1
Query: 64 ILLPFLLTCAIASAAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHANIR 237
+LL FLL A E +L L D L A Y P D+ +N+TL + + I
Sbjct: 12 LLLLFLLPAECLGA---EGRLALKLFRD-LFANYTSALRPVADTDQTLNVTLEVTLSQII 67
Query: 238 ESESTVRILAD---LQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLLNAA-ATTA 402
+ + ++L ++ W D L W+ +G + S +WRPD+VL N A A
Sbjct: 68 DMDERNQVLTLYLWIRQEWTDAYLRWDPNAYGGLDAIRIPSSLVWRPDIVLYNKADAQPP 127
Query: 403 GDYALRARVSNNGSVSXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 570
G + + ++G+V + + + +P D Q C FGS H ++D
Sbjct: 128 GSASTNVVLRHDGAVRWDAPAITRSSCRVDVAAFPFDAQHCGLTFGSWTHGGHQLD 183
>AJ278118-1|CAC20435.1| 450|Homo sapiens neuronal nicotinic
acetylcholine alpha10 subunit protein.
Length = 450
Score = 54.8 bits (126), Expect = 4e-07
Identities = 47/176 (26%), Positives = 76/176 (43%), Gaps = 7/176 (3%)
Frame = +1
Query: 64 ILLPFLLTCAIASAAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHANIR 237
+LL FLL A E +L L D L A Y P D+ +N+TL + + I
Sbjct: 12 LLLLFLLPAECLGA---EGRLALKLFRD-LFANYTSALRPVADTDQTLNVTLEVTLSQII 67
Query: 238 ESESTVRILAD---LQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLLNAA-ATTA 402
+ + ++L ++ W D L W+ +G + S +WRPD+VL N A A
Sbjct: 68 DMDERNQVLTLYLWIRQEWTDAYLRWDPNAYGGLDAIRIPSSLVWRPDIVLYNKADAQPP 127
Query: 403 GDYALRARVSNNGSVSXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 570
G + + ++G+V + + + +P D Q C FGS H ++D
Sbjct: 128 GSASTNVVLRHDGAVRWDAPAITRSSCRVDVAAFPFDAQHCGLTFGSWTHGGHQLD 183
>AF512521-1|AAO20969.1| 411|Homo sapiens ligand-gated ion channel
subunit protein.
Length = 411
Score = 54.8 bits (126), Expect = 4e-07
Identities = 28/101 (27%), Positives = 49/101 (48%)
Frame = +1
Query: 271 LQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVS 450
L+++W+D RL+WN + E LW P + +L A D + +ARV +G V
Sbjct: 86 LRLSWLDTRLAWNTSAHPRHAITLPWESLWTPRLTILEALWVDWRDQSPQARVDQDGHVK 145
Query: 451 XIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDF 573
L T + +L ++P D C+ F + + + E++F
Sbjct: 146 LNLALTTETNCNFELLHFPRDHSNCSLSFYALSNTAMELEF 186
>AF327367-1|AAK14333.1| 450|Homo sapiens nicotinic acetylcholine
receptor subunit alpha 10 protein.
Length = 450
Score = 54.8 bits (126), Expect = 4e-07
Identities = 47/176 (26%), Positives = 76/176 (43%), Gaps = 7/176 (3%)
Frame = +1
Query: 64 ILLPFLLTCAIASAAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHANIR 237
+LL FLL A E +L L D L A Y P D+ +N+TL + + I
Sbjct: 12 LLLLFLLPAECLGA---EGRLALKLFRD-LFANYTSALRPVADTDQTLNVTLEVTLSQII 67
Query: 238 ESESTVRILAD---LQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLLNAA-ATTA 402
+ + ++L ++ W D L W+ +G + S +WRPD+VL N A A
Sbjct: 68 DMDERNQVLTLYLWIRQEWTDAYLRWDPNAYGGLDAIRIPSSLVWRPDIVLYNKADAQPP 127
Query: 403 GDYALRARVSNNGSVSXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 570
G + + ++G+V + + + +P D Q C FGS H ++D
Sbjct: 128 GSASTNVVLRHDGAVRWDAPAITRSSCRVDVAAFPFDAQHCGLTFGSWTHGGHQLD 183
>AF199235-1|AAG00795.2| 450|Homo sapiens nicotinic acetylcholine
receptor subunit alpha 10 protein.
Length = 450
Score = 54.8 bits (126), Expect = 4e-07
Identities = 47/176 (26%), Positives = 76/176 (43%), Gaps = 7/176 (3%)
Frame = +1
Query: 64 ILLPFLLTCAIASAAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHANIR 237
+LL FLL A E +L L D L A Y P D+ +N+TL + + I
Sbjct: 12 LLLLFLLPAECLGA---EGRLALKLFRD-LFANYTSALRPVADTDQTLNVTLEVTLSQII 67
Query: 238 ESESTVRILAD---LQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLLNAA-ATTA 402
+ + ++L ++ W D L W+ +G + S +WRPD+VL N A A
Sbjct: 68 DMDERNQVLTLYLWIRQEWTDAYLRWDPNAYGGLDAIRIPSSLVWRPDIVLYNKADAQPP 127
Query: 403 GDYALRARVSNNGSVSXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 570
G + + ++G+V + + + +P D Q C FGS H ++D
Sbjct: 128 GSASTNVVLRHDGAVRWDAPAITRSSCRVDVAAFPFDAQHCGLTFGSWTHGGHQLD 183
>BC113575-1|AAI13576.1| 479|Homo sapiens cholinergic receptor,
nicotinic, alpha 9 protein.
Length = 479
Score = 54.4 bits (125), Expect = 5e-07
Identities = 38/163 (23%), Positives = 75/163 (46%), Gaps = 7/163 (4%)
Frame = +1
Query: 103 AAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHANIRESESTVRILAD-- 270
AAE + + + L Y P D+ V+N+TL + + I++ + +IL
Sbjct: 22 AAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQITLSQIKDMDERNQILTAYL 81
Query: 271 -LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGD-YALRARVSNNG 441
++ W D L+W+ ++ G + + S+ +WRPD+VL N A + + + +G
Sbjct: 82 WIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKADDESSEPVNTNVVLRYDG 141
Query: 442 SVSXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 570
++ + + + +P D Q C FGS +N +++D
Sbjct: 142 LITWDAPAITKSSCVVDVTYFPFDNQQCNLTFGSWTYNGNQVD 184
>BC113549-1|AAI13550.1| 479|Homo sapiens cholinergic receptor,
nicotinic, alpha 9 protein.
Length = 479
Score = 54.4 bits (125), Expect = 5e-07
Identities = 38/163 (23%), Positives = 75/163 (46%), Gaps = 7/163 (4%)
Frame = +1
Query: 103 AAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHANIRESESTVRILAD-- 270
AAE + + + L Y P D+ V+N+TL + + I++ + +IL
Sbjct: 22 AAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQITLSQIKDMDERNQILTAYL 81
Query: 271 -LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGD-YALRARVSNNG 441
++ W D L+W+ ++ G + + S+ +WRPD+VL N A + + + +G
Sbjct: 82 WIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKADDESSEPVNTNVVLRYDG 141
Query: 442 SVSXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 570
++ + + + +P D Q C FGS +N +++D
Sbjct: 142 LITWDAPAITKSSCVVDVTYFPFDNQQCNLTFGSWTYNGNQVD 184
>AY123244-1|AAM74523.1| 479|Homo sapiens nicotinic acetylcholine
receptor subunit alpha 9 protein.
Length = 479
Score = 54.4 bits (125), Expect = 5e-07
Identities = 38/163 (23%), Positives = 75/163 (46%), Gaps = 7/163 (4%)
Frame = +1
Query: 103 AAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHANIRESESTVRILAD-- 270
AAE + + + L Y P D+ V+N+TL + + I++ + +IL
Sbjct: 22 AAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQITLSQIKDMDERNQILTAYL 81
Query: 271 -LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGD-YALRARVSNNG 441
++ W D L+W+ ++ G + + S+ +WRPD+VL N A + + + +G
Sbjct: 82 WIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKADDESSEPVNTNVVLRYDG 141
Query: 442 SVSXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 570
++ + + + +P D Q C FGS +N +++D
Sbjct: 142 LITWDAPAITKSSCVVDVTYFPFDNQQCNLTFGSWTYNGNQVD 184
>AJ243342-1|CAB65091.1| 479|Homo sapiens nicotinic acetylcholine
receptor alpha 9 subunit protein.
Length = 479
Score = 54.4 bits (125), Expect = 5e-07
Identities = 38/163 (23%), Positives = 75/163 (46%), Gaps = 7/163 (4%)
Frame = +1
Query: 103 AAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHANIRESESTVRILAD-- 270
AAE + + + L Y P D+ V+N+TL + + I++ + +IL
Sbjct: 22 AAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQITLSQIKDMDERNQILTAYL 81
Query: 271 -LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGD-YALRARVSNNG 441
++ W D L+W+ ++ G + + S+ +WRPD+VL N A + + + +G
Sbjct: 82 WIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKADDESSEPVNTNVVLRYDG 141
Query: 442 SVSXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 570
++ + + + +P D Q C FGS +N +++D
Sbjct: 142 LITWDAPAITKSSCVVDVTYFPFDNQQCNLTFGSWTYNGNQVD 184
>AF227732-1|AAF61920.1| 470|Homo sapiens nicotinic acetylcholine
receptor alpha 9 subunit protein.
Length = 470
Score = 54.4 bits (125), Expect = 5e-07
Identities = 38/163 (23%), Positives = 75/163 (46%), Gaps = 7/163 (4%)
Frame = +1
Query: 103 AAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHANIRESESTVRILAD-- 270
AAE + + + L Y P D+ V+N+TL + + I++ + +IL
Sbjct: 16 AAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQITLSQIKDMDERNQILTAYL 75
Query: 271 -LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGD-YALRARVSNNG 441
++ W D L+W+ ++ G + + S+ +WRPD+VL N A + + + +G
Sbjct: 76 WIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKADDESSEPVNTNVVLRYDG 135
Query: 442 SVSXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 570
++ + + + +P D Q C FGS +N +++D
Sbjct: 136 LITWDAPAITKSSCVVDVTYFPFDNQQCNLTFGSWTYNGNQVD 178
>AC118275-1|AAY40986.1| 479|Homo sapiens unknown protein.
Length = 479
Score = 54.4 bits (125), Expect = 5e-07
Identities = 38/163 (23%), Positives = 75/163 (46%), Gaps = 7/163 (4%)
Frame = +1
Query: 103 AAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHANIRESESTVRILAD-- 270
AAE + + + L Y P D+ V+N+TL + + I++ + +IL
Sbjct: 22 AAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQITLSQIKDMDERNQILTAYL 81
Query: 271 -LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGD-YALRARVSNNG 441
++ W D L+W+ ++ G + + S+ +WRPD+VL N A + + + +G
Sbjct: 82 WIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKADDESSEPVNTNVVLRYDG 141
Query: 442 SVSXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 570
++ + + + +P D Q C FGS +N +++D
Sbjct: 142 LITWDAPAITKSSCVVDVTYFPFDNQQCNLTFGSWTYNGNQVD 184
>AB223030-1|BAE19924.1| 411|Homo sapiens ligand-gated ion-channel
receptor L2 protein.
Length = 411
Score = 54.4 bits (125), Expect = 5e-07
Identities = 28/101 (27%), Positives = 49/101 (48%)
Frame = +1
Query: 271 LQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVS 450
L+++W+D RL+WN + E LW P + +L A D + +ARV +G V
Sbjct: 86 LRLSWLDTRLAWNTSAHPRHAITLPWESLWTPRLTILEALWVDWRDQSPQARVDQDGHVK 145
Query: 451 XIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDF 573
L T + +L ++P D C+ F + + + E++F
Sbjct: 146 LNLALATETNCNFELLHFPRDHSNCSLSFYALSNTAMELEF 186
>S82612-1|AAB37533.2| 478|Homo sapiens 5-hydroxytryptamine type 3AS
receptor subunit protein.
Length = 478
Score = 53.6 bits (123), Expect = 9e-07
Identities = 39/175 (22%), Positives = 74/175 (42%), Gaps = 6/175 (3%)
Frame = +1
Query: 64 ILLPFLLTCAIASAAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHL---RHA 228
+LLP LL A + +L + D LL Y + P D + +++ +
Sbjct: 12 LLLPTLLAQGEARRSRNTTRPALLRLSDYLLTNYTKGVRPVRDWRKPTTVSIDVIVYAIL 71
Query: 229 NIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAG 405
N+ E + + W D+ L WN ++ T L + ++ +W PD+++
Sbjct: 72 NVDEKNQVLTTYIWYRQYWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINELVDVGKS 131
Query: 406 DYALRARVSNNGSVSXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 570
+ + G V K L + T S+ + N+P D+Q C+ F S +H +++
Sbjct: 132 PNIPYVYIRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLHTIQDIN 186
>S77554-1|AAB33983.1| 474|Homo sapiens GABAA receptor beta 2
subunit protein.
Length = 474
Score = 53.6 bits (123), Expect = 9e-07
Identities = 44/182 (24%), Positives = 78/182 (42%), Gaps = 10/182 (5%)
Frame = +1
Query: 58 YIILLPFLLTCAIASAAECENATSLSLM---IDSLLATYDRESPPD---SKIVVNLTLHL 219
Y + F L A A + +++SL+ +D LL YD PD + V + + +
Sbjct: 9 YFGIWSFPLIIAAVCAQSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDI 68
Query: 220 RHAN-IRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAAT 396
+ + E + Q W DKRLS+N + +++LW PD LN +
Sbjct: 69 ASIDMVSEVNMDYTLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLNDKKS 128
Query: 397 TAGDYALR---ARVSNNGSVSXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEM 567
++ R+ +G+V R+ + M L +P D Q CT + S + +D++
Sbjct: 129 FVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDI 188
Query: 568 DF 573
+F
Sbjct: 189 EF 190
>S77553-1|AAB33982.1| 512|Homo sapiens GABAA receptor beta 2
subunit protein.
Length = 512
Score = 53.6 bits (123), Expect = 9e-07
Identities = 44/182 (24%), Positives = 78/182 (42%), Gaps = 10/182 (5%)
Frame = +1
Query: 58 YIILLPFLLTCAIASAAECENATSLSLM---IDSLLATYDRESPPD---SKIVVNLTLHL 219
Y + F L A A + +++SL+ +D LL YD PD + V + + +
Sbjct: 9 YFGIWSFPLIIAAVCAQSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDI 68
Query: 220 RHAN-IRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAAT 396
+ + E + Q W DKRLS+N + +++LW PD LN +
Sbjct: 69 ASIDMVSEVNMDYTLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLNDKKS 128
Query: 397 TAGDYALR---ARVSNNGSVSXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEM 567
++ R+ +G+V R+ + M L +P D Q CT + S + +D++
Sbjct: 129 FVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDI 188
Query: 568 DF 573
+F
Sbjct: 189 EF 190
>S67368-1|AAB29370.1| 474|Homo sapiens gamma-aminobutyric acid A
receptor beta 2 subunit protein.
Length = 474
Score = 53.6 bits (123), Expect = 9e-07
Identities = 44/182 (24%), Positives = 78/182 (42%), Gaps = 10/182 (5%)
Frame = +1
Query: 58 YIILLPFLLTCAIASAAECENATSLSLM---IDSLLATYDRESPPD---SKIVVNLTLHL 219
Y + F L A A + +++SL+ +D LL YD PD + V + + +
Sbjct: 9 YFGIWSFPLIIAAVCAQSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDI 68
Query: 220 RHAN-IRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAAT 396
+ + E + Q W DKRLS+N + +++LW PD LN +
Sbjct: 69 ASIDMVSEVNMDYTLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLNDKKS 128
Query: 397 TAGDYALR---ARVSNNGSVSXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEM 567
++ R+ +G+V R+ + M L +P D Q CT + S + +D++
Sbjct: 129 FVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDI 188
Query: 568 DF 573
+F
Sbjct: 189 EF 190
>BC105639-1|AAI05640.1| 474|Homo sapiens GABRB2 protein protein.
Length = 474
Score = 53.6 bits (123), Expect = 9e-07
Identities = 44/182 (24%), Positives = 78/182 (42%), Gaps = 10/182 (5%)
Frame = +1
Query: 58 YIILLPFLLTCAIASAAECENATSLSLM---IDSLLATYDRESPPD---SKIVVNLTLHL 219
Y + F L A A + +++SL+ +D LL YD PD + V + + +
Sbjct: 9 YFGIWSFPLIIAAVCAQSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDI 68
Query: 220 RHAN-IRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAAT 396
+ + E + Q W DKRLS+N + +++LW PD LN +
Sbjct: 69 ASIDMVSEVNMDYTLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLNDKKS 128
Query: 397 TAGDYALR---ARVSNNGSVSXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEM 567
++ R+ +G+V R+ + M L +P D Q CT + S + +D++
Sbjct: 129 FVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDI 188
Query: 568 DF 573
+F
Sbjct: 189 EF 190
>BC099719-1|AAH99719.1| 474|Homo sapiens GABRB2 protein protein.
Length = 474
Score = 53.6 bits (123), Expect = 9e-07
Identities = 44/182 (24%), Positives = 78/182 (42%), Gaps = 10/182 (5%)
Frame = +1
Query: 58 YIILLPFLLTCAIASAAECENATSLSLM---IDSLLATYDRESPPD---SKIVVNLTLHL 219
Y + F L A A + +++SL+ +D LL YD PD + V + + +
Sbjct: 9 YFGIWSFPLIIAAVCAQSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDI 68
Query: 220 RHAN-IRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAAT 396
+ + E + Q W DKRLS+N + +++LW PD LN +
Sbjct: 69 ASIDMVSEVNMDYTLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLNDKKS 128
Query: 397 TAGDYALR---ARVSNNGSVSXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEM 567
++ R+ +G+V R+ + M L +P D Q CT + S + +D++
Sbjct: 129 FVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDI 188
Query: 568 DF 573
+F
Sbjct: 189 EF 190
>BC099705-1|AAH99705.1| 474|Homo sapiens GABRB2 protein protein.
Length = 474
Score = 53.6 bits (123), Expect = 9e-07
Identities = 44/182 (24%), Positives = 78/182 (42%), Gaps = 10/182 (5%)
Frame = +1
Query: 58 YIILLPFLLTCAIASAAECENATSLSLM---IDSLLATYDRESPPD---SKIVVNLTLHL 219
Y + F L A A + +++SL+ +D LL YD PD + V + + +
Sbjct: 9 YFGIWSFPLIIAAVCAQSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDI 68
Query: 220 RHAN-IRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAAT 396
+ + E + Q W DKRLS+N + +++LW PD LN +
Sbjct: 69 ASIDMVSEVNMDYTLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLNDKKS 128
Query: 397 TAGDYALR---ARVSNNGSVSXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEM 567
++ R+ +G+V R+ + M L +P D Q CT + S + +D++
Sbjct: 129 FVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDI 188
Query: 568 DF 573
+F
Sbjct: 189 EF 190
>AJ003080-1|CAA05853.1| 238|Homo sapiens serotonin receptor
protein.
Length = 238
Score = 53.6 bits (123), Expect = 9e-07
Identities = 40/171 (23%), Positives = 72/171 (42%), Gaps = 6/171 (3%)
Frame = +1
Query: 64 ILLPFLLTCAIASAAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHL---RHA 228
+LLP LL A + +L + D LL Y + P D + +++ +
Sbjct: 12 LLLPTLLAQGEARRSRNTTRPALLRLSDYLLTNYRKGVRPVRDWRKPTTVSIDVIVYAIL 71
Query: 229 NIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAG 405
N+ E + + W D+ L WN ++ T L + ++ +W PD+++
Sbjct: 72 NVDEKNQVLTTYIWYRQYWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKS 131
Query: 406 DYALRARVSNNGSVSXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNS 558
+ + G V K L + T S+ + N+P D+Q C+ F S +H S
Sbjct: 132 PNIPYVYIRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLHTS 182
>M59216-1|AAA35862.1| 474|Homo sapiens gamma-aminobutyric acid
receptor beta-1 subunit protein.
Length = 474
Score = 53.2 bits (122), Expect = 1e-06
Identities = 42/180 (23%), Positives = 78/180 (43%), Gaps = 9/180 (5%)
Frame = +1
Query: 61 IILLPFLLT--CAIASAAECENATSLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRH 225
++ P ++T C S E N + + +D LL YD PD + V + + +
Sbjct: 12 LLSFPVMITMVCCAHSTNEPSNMSYVKETVDRLLKGYDIRLRPDFGGPPVDVGMRIDVAS 71
Query: 226 AN-IRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTA 402
+ + E + Q +W DKRLS++ + +++LW PD LN +
Sbjct: 72 IDMVSEVNMDYTLTMYFQQSWKDKRLSYSGIPLNLTLDNRVADQLWVPDTYFLNDKKSFV 131
Query: 403 GDYALR---ARVSNNGSVSXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDF 573
++ R+ +G+V R+ + M L +P D Q CT + S + +D+++F
Sbjct: 132 HGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEF 191
>L08485-1|AAA58490.1| 462|Homo sapiens GABA-benzodiazepine receptor
alpha-5-subunit protein.
Length = 462
Score = 52.8 bits (121), Expect = 2e-06
Identities = 39/161 (24%), Positives = 72/161 (44%), Gaps = 7/161 (4%)
Frame = +1
Query: 115 ENATSLSLMIDSLLATYDRESPPD--SKIV-VNLTLHLRHAN-IRESESTVRILADLQMN 282
+N T + ++D LL YD P +I V +++ + ++E I + +
Sbjct: 44 DNITIFTRILDGLLDGYDNRLRPGLGERITQVRTDIYVTSFGPVSDTEMEYTIDVFFRQS 103
Query: 283 WIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSX 453
W D+RL + + + ++W PD N + A + R+ ++G++
Sbjct: 104 WKDERLRFKGPMQRLPLNNLLASKIWTPDTFFHNGKKSIAHNMTTPNKLLRLEDDGTLLY 163
Query: 454 IKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFV 576
RL IS MQL+++P D C KFGS + + E+ +V
Sbjct: 164 TMRLTISAECPMQLEDFPMDAHACPLKFGSYAYPNSEVVYV 204
>D49394-1|BAA08387.1| 478|Homo sapiens serotonin 5-HT3 receptor
protein.
Length = 478
Score = 52.8 bits (121), Expect = 2e-06
Identities = 39/175 (22%), Positives = 74/175 (42%), Gaps = 6/175 (3%)
Frame = +1
Query: 64 ILLPFLLTCAIASAAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHL---RHA 228
+LLP LL A + +L + D LL Y + P D + +++ +
Sbjct: 12 LLLPTLLAQGEARRSRNTTRPALLRLSDYLLTNYRKGVRPVRDWRKPTTVSIDVIVYAIL 71
Query: 229 NIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAG 405
N+ E + + W D+ L WN ++ T L + ++ +W PD+++
Sbjct: 72 NVDEKNQVLTTYIWYRQYWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKS 131
Query: 406 DYALRARVSNNGSVSXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 570
+ + G V K L + T S+ + N+P D+Q C+ F S +H +++
Sbjct: 132 PNIPYVYIRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLHTIQDIN 186
>BT009830-1|AAP88832.1| 462|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 5 protein.
Length = 462
Score = 52.8 bits (121), Expect = 2e-06
Identities = 39/161 (24%), Positives = 72/161 (44%), Gaps = 7/161 (4%)
Frame = +1
Query: 115 ENATSLSLMIDSLLATYDRESPPD--SKIV-VNLTLHLRHAN-IRESESTVRILADLQMN 282
+N T + ++D LL YD P +I V +++ + ++E I + +
Sbjct: 44 DNITIFTRILDGLLDGYDNRLRPGLGERITQVRTDIYVTSFGPVSDTEMEYTIDVFFRQS 103
Query: 283 WIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSX 453
W D+RL + + + ++W PD N + A + R+ ++G++
Sbjct: 104 WKDERLRFKGPMQRLPLNNLLASKIWTPDTFFHNGKKSIAHNMTTPNKLLRLEDDGTLLY 163
Query: 454 IKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFV 576
RL IS MQL+++P D C KFGS + + E+ +V
Sbjct: 164 TMRLTISAECPMQLEDFPMDAHACPLKFGSYAYPNSEVVYV 204
>BT007204-1|AAP35868.1| 484|Homo sapiens 5-hydroxytryptamine
(serotonin) receptor 3A protein.
Length = 484
Score = 52.8 bits (121), Expect = 2e-06
Identities = 39/175 (22%), Positives = 74/175 (42%), Gaps = 6/175 (3%)
Frame = +1
Query: 64 ILLPFLLTCAIASAAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHL---RHA 228
+LLP LL A + +L + D LL Y + P D + +++ +
Sbjct: 18 LLLPTLLAQGEARRSRNTTRPALLRLSDYLLTNYRKGVRPVRDWRKPTTVSIDVIVYAIL 77
Query: 229 NIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAG 405
N+ E + + W D+ L WN ++ T L + ++ +W PD+++
Sbjct: 78 NVDEKNQVLTTYIWYRQYWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKS 137
Query: 406 DYALRARVSNNGSVSXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 570
+ + G V K L + T S+ + N+P D+Q C+ F S +H +++
Sbjct: 138 PNIPYVYIRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLHTIQDIN 192
>BC113422-1|AAI13423.1| 462|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 5 protein.
Length = 462
Score = 52.8 bits (121), Expect = 2e-06
Identities = 39/161 (24%), Positives = 72/161 (44%), Gaps = 7/161 (4%)
Frame = +1
Query: 115 ENATSLSLMIDSLLATYDRESPPD--SKIV-VNLTLHLRHAN-IRESESTVRILADLQMN 282
+N T + ++D LL YD P +I V +++ + ++E I + +
Sbjct: 44 DNITIFTRILDGLLDGYDNRLRPGLGERITQVRTDIYVTSFGPVSDTEMEYTIDVFFRQS 103
Query: 283 WIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSX 453
W D+RL + + + ++W PD N + A + R+ ++G++
Sbjct: 104 WKDERLRFKGPMQRLPLNNLLASKIWTPDTFFHNGKKSIAHNMTTPNKLLRLEDDGTLLY 163
Query: 454 IKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFV 576
RL IS MQL+++P D C KFGS + + E+ +V
Sbjct: 164 TMRLTISAECPMQLEDFPMDAHACPLKFGSYAYPNSEVVYV 204
>BC111979-1|AAI11980.1| 462|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 5, precursor protein.
Length = 462
Score = 52.8 bits (121), Expect = 2e-06
Identities = 39/161 (24%), Positives = 72/161 (44%), Gaps = 7/161 (4%)
Frame = +1
Query: 115 ENATSLSLMIDSLLATYDRESPPD--SKIV-VNLTLHLRHAN-IRESESTVRILADLQMN 282
+N T + ++D LL YD P +I V +++ + ++E I + +
Sbjct: 44 DNITIFTRILDGLLDGYDNRLRPGLGERITQVRTDIYVTSFGPVSDTEMEYTIDVFFRQS 103
Query: 283 WIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSX 453
W D+RL + + + ++W PD N + A + R+ ++G++
Sbjct: 104 WKDERLRFKGPMQRLPLNNLLASKIWTPDTFFHNGKKSIAHNMTTPNKLLRLEDDGTLLY 163
Query: 454 IKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFV 576
RL IS MQL+++P D C KFGS + + E+ +V
Sbjct: 164 TMRLTISAECPMQLEDFPMDAHACPLKFGSYAYPNSEVVYV 204
>BC004453-1|AAH04453.2| 478|Homo sapiens 5-hydroxytryptamine
(serotonin) receptor 3A protein.
Length = 478
Score = 52.8 bits (121), Expect = 2e-06
Identities = 39/175 (22%), Positives = 74/175 (42%), Gaps = 6/175 (3%)
Frame = +1
Query: 64 ILLPFLLTCAIASAAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHL---RHA 228
+LLP LL A + +L + D LL Y + P D + +++ +
Sbjct: 12 LLLPTLLAQGEARRSRNTTRPALLRLSDYLLTNYRKGVRPVRDWRKPTTVSIDVIVYAIL 71
Query: 229 NIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAG 405
N+ E + + W D+ L WN ++ T L + ++ +W PD+++
Sbjct: 72 NVDEKNQVLTTYIWYRQYWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKS 131
Query: 406 DYALRARVSNNGSVSXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 570
+ + G V K L + T S+ + N+P D+Q C+ F S +H +++
Sbjct: 132 PNIPYVYIRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLHTIQDIN 186
>BC002354-1|AAH02354.1| 478|Homo sapiens 5-hydroxytryptamine
(serotonin) receptor 3A protein.
Length = 478
Score = 52.8 bits (121), Expect = 2e-06
Identities = 39/175 (22%), Positives = 74/175 (42%), Gaps = 6/175 (3%)
Frame = +1
Query: 64 ILLPFLLTCAIASAAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHL---RHA 228
+LLP LL A + +L + D LL Y + P D + +++ +
Sbjct: 12 LLLPTLLAQGEARRSRNTTRPALLRLSDYLLTNYRKGVRPVRDWRKPTTVSIDVIVYAIL 71
Query: 229 NIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAG 405
N+ E + + W D+ L WN ++ T L + ++ +W PD+++
Sbjct: 72 NVDEKNQVLTTYIWYRQYWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKS 131
Query: 406 DYALRARVSNNGSVSXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 570
+ + G V K L + T S+ + N+P D+Q C+ F S +H +++
Sbjct: 132 PNIPYVYIRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLHTIQDIN 186
>AJ005205-1|CAA06442.3| 478|Homo sapiens serotonin 3 receptor
protein.
Length = 478
Score = 52.8 bits (121), Expect = 2e-06
Identities = 39/175 (22%), Positives = 74/175 (42%), Gaps = 6/175 (3%)
Frame = +1
Query: 64 ILLPFLLTCAIASAAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHL---RHA 228
+LLP LL A + +L + D LL Y + P D + +++ +
Sbjct: 12 LLLPTLLAQGEARRSRNTTRPALLRLSDYLLTNYRKGVRPVRDWRKPTTVSIDVIVYAIL 71
Query: 229 NIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAG 405
N+ E + + W D+ L WN ++ T L + ++ +W PD+++
Sbjct: 72 NVDEKNQVLTTYIWYRQYWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKS 131
Query: 406 DYALRARVSNNGSVSXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 570
+ + G V K L + T S+ + N+P D+Q C+ F S +H +++
Sbjct: 132 PNIPYVYIRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLHTIQDIN 186
>AJ003079-1|CAA05852.1| 478|Homo sapiens 5-hydroxytryptamine3
receptor protein.
Length = 478
Score = 52.8 bits (121), Expect = 2e-06
Identities = 39/175 (22%), Positives = 74/175 (42%), Gaps = 6/175 (3%)
Frame = +1
Query: 64 ILLPFLLTCAIASAAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHL---RHA 228
+LLP LL A + +L + D LL Y + P D + +++ +
Sbjct: 12 LLLPTLLAQGEARRSRNTTRPALLRLSDYLLTNYRKGVRPVRDWRKPTTVSIDVIVYAIL 71
Query: 229 NIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAG 405
N+ E + + W D+ L WN ++ T L + ++ +W PD+++
Sbjct: 72 NVDEKNQVLTTYIWYRQYWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKS 131
Query: 406 DYALRARVSNNGSVSXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 570
+ + G V K L + T S+ + N+P D+Q C+ F S +H +++
Sbjct: 132 PNIPYVYIRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLHTIQDIN 186
>AJ003078-1|CAA05851.1| 510|Homo sapiens serotonin receptor
protein.
Length = 510
Score = 52.8 bits (121), Expect = 2e-06
Identities = 39/175 (22%), Positives = 74/175 (42%), Gaps = 6/175 (3%)
Frame = +1
Query: 64 ILLPFLLTCAIASAAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHL---RHA 228
+LLP LL A + +L + D LL Y + P D + +++ +
Sbjct: 12 LLLPTLLAQGEARRSRNTTRPALLRLSDYLLTNYRKGVRPVRDWRKPTTVSIDVIVYAIL 71
Query: 229 NIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAG 405
N+ E + + W D+ L WN ++ T L + ++ +W PD+++
Sbjct: 72 NVDEKNQVLTTYIWYRQYWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKS 131
Query: 406 DYALRARVSNNGSVSXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 570
+ + G V K L + T S+ + N+P D+Q C+ F S +H +++
Sbjct: 132 PNIPYVYIRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLHTIQDIN 186
>AF498984-1|AAM21131.1| 478|Homo sapiens 5-hydroxytryptamine
receptor 3A protein.
Length = 478
Score = 52.8 bits (121), Expect = 2e-06
Identities = 39/175 (22%), Positives = 74/175 (42%), Gaps = 6/175 (3%)
Frame = +1
Query: 64 ILLPFLLTCAIASAAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHL---RHA 228
+LLP LL A + +L + D LL Y + P D + +++ +
Sbjct: 12 LLLPTLLAQGEARRSRNTTRPALLRLSDYLLTNYRKGVRPVRDWRKPTTVSIDVIVYAIL 71
Query: 229 NIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAG 405
N+ E + + W D+ L WN ++ T L + ++ +W PD+++
Sbjct: 72 NVDEKNQVLTTYIWYRQYWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKS 131
Query: 406 DYALRARVSNNGSVSXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 570
+ + G V K L + T S+ + N+P D+Q C+ F S +H +++
Sbjct: 132 PNIPYVYIRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLHTIQDIN 186
>Z23141-1|CAA80672.1| 479|Homo sapiens cholinergic receptor,
nicotinic, alpha polypeptide 7 protein.
Length = 479
Score = 52.4 bits (120), Expect = 2e-06
Identities = 32/123 (26%), Positives = 55/123 (44%), Gaps = 3/123 (2%)
Frame = +1
Query: 271 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSNNGS 444
LQM+W D L WN E+ G T ++W+PD++L N+A + V+++G
Sbjct: 55 LQMSWTDHYLQWNVSEYPGVKTVRFPDGQIWKPDILLYNSADERFDATFHTNVLVNSSGH 114
Query: 445 VSXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDKR-IYSMFESGAWG 621
+ + + + +P D+Q C KFGS + +D + + I +G W
Sbjct: 115 CQYLPPGIFKSSCYIDVRWFPFDVQHCKLKFGSWSYGGWSLDLQMQEADISGYIPNGEWD 174
Query: 622 CDG 630
G
Sbjct: 175 LVG 177
>Y08420-1|CAA69697.1| 502|Homo sapiens nicotinic acetylcholine
receptor alpha7 subunit precursor protein.
Length = 502
Score = 52.4 bits (120), Expect = 2e-06
Identities = 32/123 (26%), Positives = 55/123 (44%), Gaps = 3/123 (2%)
Frame = +1
Query: 271 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSNNGS 444
LQM+W D L WN E+ G T ++W+PD++L N+A + V+++G
Sbjct: 78 LQMSWTDHYLQWNVSEYPGVKTVRFPDGQIWKPDILLYNSADERFDATFHTNVLVNSSGH 137
Query: 445 VSXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDKR-IYSMFESGAWG 621
+ + + + +P D+Q C KFGS + +D + + I +G W
Sbjct: 138 CQYLPPGIFKSSCYIDVRWFPFDVQHCKLKFGSWSYGGWSLDLQMQEADISGYIPNGEWD 197
Query: 622 CDG 630
G
Sbjct: 198 LVG 200
>X70297-1|CAA49778.1| 502|Homo sapiens neuronal nicotinic
acetylocholine receptor alpha-7 subunit protein.
Length = 502
Score = 52.4 bits (120), Expect = 2e-06
Identities = 32/123 (26%), Positives = 55/123 (44%), Gaps = 3/123 (2%)
Frame = +1
Query: 271 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSNNGS 444
LQM+W D L WN E+ G T ++W+PD++L N+A + V+++G
Sbjct: 78 LQMSWTDHYLQWNVSEYPGVKTVRFPDGQIWKPDILLYNSADERFDATFHTNVLVNSSGH 137
Query: 445 VSXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDKR-IYSMFESGAWG 621
+ + + + +P D+Q C KFGS + +D + + I +G W
Sbjct: 138 CQYLPPGIFKSSCYIDVRWFPFDVQHCKLKFGSWSYGGWSLDLQMQEADISGYIPNGEWD 197
Query: 622 CDG 630
G
Sbjct: 198 LVG 200
>X14767-1|CAA32875.1| 474|Homo sapiens GABA-A receptor beta 1
subunit protein.
Length = 474
Score = 52.4 bits (120), Expect = 2e-06
Identities = 42/180 (23%), Positives = 77/180 (42%), Gaps = 9/180 (5%)
Frame = +1
Query: 61 IILLPFLLT--CAIASAAECENATSLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRH 225
++ P ++T C S E N + +D LL YD PD + V + + +
Sbjct: 12 LLSFPVMITMVCCAHSTNEPSNMPYVKETVDRLLKGYDIRLRPDFGGPPVDVGMRIDVAS 71
Query: 226 AN-IRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTA 402
+ + E + Q +W DKRLS++ + +++LW PD LN +
Sbjct: 72 IDMVSEVNMDYTLTMYFQQSWKDKRLSYSGIPLNLTLDNRVADQLWVPDTYFLNDKKSFV 131
Query: 403 GDYALR---ARVSNNGSVSXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDF 573
++ R+ +G+V R+ + M L +P D Q CT + S + +D+++F
Sbjct: 132 HGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEF 191
>U62436-1|AAB40114.1| 502|Homo sapiens nicotinic acetylcholine
receptor alpha7 subunit precursor protein.
Length = 502
Score = 52.4 bits (120), Expect = 2e-06
Identities = 32/123 (26%), Positives = 55/123 (44%), Gaps = 3/123 (2%)
Frame = +1
Query: 271 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSNNGS 444
LQM+W D L WN E+ G T ++W+PD++L N+A + V+++G
Sbjct: 78 LQMSWTDHYLQWNVSEYPGVKTVRFPDGQIWKPDILLYNSADERFDATFHTNVLVNSSGH 137
Query: 445 VSXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDKR-IYSMFESGAWG 621
+ + + + +P D+Q C KFGS + +D + + I +G W
Sbjct: 138 CQYLPPGIFKSSCYIDVRWFPFDVQHCKLKFGSWSYGGWSLDLQMQEADISGYIPNGEWD 197
Query: 622 CDG 630
G
Sbjct: 198 LVG 200
>AJ586911-1|CAE52911.1| 502|Homo sapiens nicotinic acetylcholine
alpha-7 subunit protein.
Length = 502
Score = 52.4 bits (120), Expect = 2e-06
Identities = 32/123 (26%), Positives = 55/123 (44%), Gaps = 3/123 (2%)
Frame = +1
Query: 271 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSNNGS 444
LQM+W D L WN E+ G T ++W+PD++L N+A + V+++G
Sbjct: 78 LQMSWTDHYLQWNVSEYPGVKTVRFPDGQIWKPDILLYNSADERFDATFHTNVLVNSSGH 137
Query: 445 VSXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDKR-IYSMFESGAWG 621
+ + + + +P D+Q C KFGS + +D + + I +G W
Sbjct: 138 CQYLPPGIFKSSCYIDVRWFPFDVQHCKLKFGSWSYGGWSLDLQMQEADISGYIPNGEWD 197
Query: 622 CDG 630
G
Sbjct: 198 LVG 200
>X55019-1|CAA38759.1| 517|Homo sapiens acetylcholine receptor delta
subunit protein.
Length = 517
Score = 51.6 bits (118), Expect = 4e-06
Identities = 37/142 (26%), Positives = 66/142 (46%), Gaps = 7/142 (4%)
Frame = +1
Query: 163 YDRESPP----DSKIVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEWG- 324
Y++E P + + V L L L + +++E E T+ ++ W D RL WNA E+G
Sbjct: 38 YNKELRPVAHKEESVDVALALTLSNLISLKEVEETLTTNVWIEHGWTDNRLKWNAEEFGN 97
Query: 325 CSTWLVSSERLWRPDVVL-LNAAATTAGDYALRARVSNNGSVSXIKRLDISTPISMQLDN 501
S + + +W P++VL N + Y+ V + G V + + + +
Sbjct: 98 ISVLRLPPDMVWLPEIVLENNNDGSFQISYSCNVLVYHYGFVYWLPPAIFRSSCPISVTY 157
Query: 502 WPNDMQTCTFKFGSRMHNSDEM 567
+P D Q C+ KF S + + E+
Sbjct: 158 FPFDWQNCSLKFSSLKYTAKEI 179
>BC093925-1|AAH93925.1| 517|Homo sapiens cholinergic receptor,
nicotinic, delta protein.
Length = 517
Score = 51.6 bits (118), Expect = 4e-06
Identities = 37/142 (26%), Positives = 66/142 (46%), Gaps = 7/142 (4%)
Frame = +1
Query: 163 YDRESPP----DSKIVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEWG- 324
Y++E P + + V L L L + +++E E T+ ++ W D RL WNA E+G
Sbjct: 38 YNKELRPVAHKEESVDVALALTLSNLISLKEVEETLTTNVWIEHGWTDNRLKWNAEEFGN 97
Query: 325 CSTWLVSSERLWRPDVVL-LNAAATTAGDYALRARVSNNGSVSXIKRLDISTPISMQLDN 501
S + + +W P++VL N + Y+ V + G V + + + +
Sbjct: 98 ISVLRLPPDMVWLPEIVLENNNDGSFQISYSCNVLVYHYGFVYWLPPAIFRSSCPISVTY 157
Query: 502 WPNDMQTCTFKFGSRMHNSDEM 567
+P D Q C+ KF S + + E+
Sbjct: 158 FPFDWQNCSLKFSSLKYTAKEI 179
>BC093923-1|AAH93923.1| 517|Homo sapiens cholinergic receptor,
nicotinic, delta protein.
Length = 517
Score = 51.6 bits (118), Expect = 4e-06
Identities = 37/142 (26%), Positives = 66/142 (46%), Gaps = 7/142 (4%)
Frame = +1
Query: 163 YDRESPP----DSKIVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEWG- 324
Y++E P + + V L L L + +++E E T+ ++ W D RL WNA E+G
Sbjct: 38 YNKELRPVAHKEESVDVALALTLSNLISLKEVEETLTTNVWIEHGWTDNRLKWNAEEFGN 97
Query: 325 CSTWLVSSERLWRPDVVL-LNAAATTAGDYALRARVSNNGSVSXIKRLDISTPISMQLDN 501
S + + +W P++VL N + Y+ V + G V + + + +
Sbjct: 98 ISVLRLPPDMVWLPEIVLENNNDGSFQISYSCNVLVYHYGFVYWLPPAIFRSSCPISVTY 157
Query: 502 WPNDMQTCTFKFGSRMHNSDEM 567
+P D Q C+ KF S + + E+
Sbjct: 158 FPFDWQNCSLKFSSLKYTAKEI 179
>AC092165-2|AAY24102.1| 517|Homo sapiens unknown protein.
Length = 517
Score = 51.6 bits (118), Expect = 4e-06
Identities = 37/142 (26%), Positives = 66/142 (46%), Gaps = 7/142 (4%)
Frame = +1
Query: 163 YDRESPP----DSKIVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEWG- 324
Y++E P + + V L L L + +++E E T+ ++ W D RL WNA E+G
Sbjct: 38 YNKELRPVAHKEESVDVALALTLSNLISLKEVEETLTTNVWIEHGWTDNRLKWNAEEFGN 97
Query: 325 CSTWLVSSERLWRPDVVL-LNAAATTAGDYALRARVSNNGSVSXIKRLDISTPISMQLDN 501
S + + +W P++VL N + Y+ V + G V + + + +
Sbjct: 98 ISVLRLPPDMVWLPEIVLENNNDGSFQISYSCNVLVYHYGFVYWLPPAIFRSSCPISVTY 157
Query: 502 WPNDMQTCTFKFGSRMHNSDEM 567
+P D Q C+ KF S + + E+
Sbjct: 158 FPFDWQNCSLKFSSLKYTAKEI 179
>U40583-1|AAA83561.1| 502|Homo sapiens alpha 7 neuronal nicotinic
acetylcholine receptor protein.
Length = 502
Score = 51.2 bits (117), Expect = 5e-06
Identities = 32/123 (26%), Positives = 54/123 (43%), Gaps = 3/123 (2%)
Frame = +1
Query: 271 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSNNGS 444
LQM+W D L WN E+ G T ++W+PD++L N+A + V+ +G
Sbjct: 78 LQMSWTDHYLQWNVSEYPGVKTVRFPDGQIWKPDILLYNSADERFDATFHTNVLVNPSGH 137
Query: 445 VSXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDKR-IYSMFESGAWG 621
+ + + + +P D+Q C KFGS + +D + + I +G W
Sbjct: 138 CQYLPPGIFKSSCYIDVRWFPFDVQHCKLKFGSWSYGGWSLDLQMQEADISGYIPNGEWD 197
Query: 622 CDG 630
G
Sbjct: 198 LVG 200
>AK122638-1|BAC85499.1| 266|Homo sapiens yte protein of 76kDa)
(LCP2). protein.
Length = 266
Score = 51.2 bits (117), Expect = 5e-06
Identities = 26/89 (29%), Positives = 42/89 (47%)
Frame = +1
Query: 271 LQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVS 450
L+++W+D RL+WN + E LW P + +L A D + +ARV +G V
Sbjct: 87 LRLSWLDTRLAWNTSAHPRHAITLPWESLWTPRLTILEALWVDWRDQSPQARVDQDGHVK 146
Query: 451 XIKRLDISTPISMQLDNWPNDMQTCTFKF 537
L T + +L ++P D C+ F
Sbjct: 147 LNLALTTETNCNFELLHFPRDHSNCSLSF 175
>AF385585-1|AAK68111.1| 502|Homo sapiens nicotinic cholinergic
receptor alpha 7 protein.
Length = 502
Score = 51.2 bits (117), Expect = 5e-06
Identities = 32/123 (26%), Positives = 54/123 (43%), Gaps = 3/123 (2%)
Frame = +1
Query: 271 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSNNGS 444
LQM+W D L WN E+ G T ++W+PD++L N+A + V+ +G
Sbjct: 78 LQMSWTDHYLQWNVSEYPGVKTVRFPDGQIWKPDILLYNSADERFDATFHTNVLVNPSGH 137
Query: 445 VSXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDKR-IYSMFESGAWG 621
+ + + + +P D+Q C KFGS + +D + + I +G W
Sbjct: 138 CQYLPPGIFKSSCYIDVRWFPFDVQHCKLKFGSWSYGGWSLDLQMQEADISGYIPNGEWD 197
Query: 622 CDG 630
G
Sbjct: 198 LVG 200
>BC028629-1|AAH28629.1| 492|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 3 protein.
Length = 492
Score = 50.0 bits (114), Expect = 1e-05
Identities = 36/158 (22%), Positives = 69/158 (43%), Gaps = 7/158 (4%)
Frame = +1
Query: 115 ENATSLSLMIDSLLATYDRESPP---DSKIVVNLTLHLRHAN-IRESESTVRILADLQMN 282
+N T + ++D LL YD P D+ V +++ + +++ I +
Sbjct: 62 DNITIFTRILDRLLDGYDNRLRPGLGDAVTEVKTDIYVTSFGPVSDTDMEYTIDVFFRQT 121
Query: 283 WIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSX 453
W D+RL ++ + + ++W PD N + A + R+ +NG++
Sbjct: 122 WHDERLKFDGPMKILPLNNLLASKIWTPDTFFHNGKKSVAHNMTTPNKLLRLVDNGTLPY 181
Query: 454 IKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEM 567
RL I M L+++P D+ C KFGS + + E+
Sbjct: 182 TMRLTIHAECPMHLEDFPMDVHACPLKFGSYAYTTAEV 219
>S82769-1|AAB39369.1| 467|Homo sapiens GABAA receptor gamma 3
subunit protein.
Length = 467
Score = 49.6 bits (113), Expect = 1e-05
Identities = 39/172 (22%), Positives = 72/172 (41%), Gaps = 7/172 (4%)
Frame = +1
Query: 124 TSLSLMIDSLLATYDRESPPDSKI---VVNLTLHLRHAN-IRESESTVRILADLQMNWID 291
T ++L+++ LL YD++ PD I V+++ +++ + +I W D
Sbjct: 45 TDVTLILNKLLREYDKKLRPDIGIKPTVIDVDIYVNSIGPVSSINMEYQIDIFFAQTWTD 104
Query: 292 KRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSXIKR 462
RL +N+ + +W PD + N+ A R+ N+G + R
Sbjct: 105 SRLRFNSTMKILTLNSNMVGLIWIPDTIFRNSKTAEAHWITTPNQLLRIWNDGKILYTLR 164
Query: 463 LDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDKRIYSMFESGAW 618
L I+ +QL N+P D +C F S + +EM + K + +W
Sbjct: 165 LTINAECQLQLHNFPMDEHSCPLIFSSYGYPKEEMIYRWRKNSVEAADQKSW 216
>S62908-1|AAB27279.1| 492|Homo sapiens gamma-aminobutyric acidA
receptor alpha 3 subunit protein.
Length = 492
Score = 49.6 bits (113), Expect = 1e-05
Identities = 36/158 (22%), Positives = 69/158 (43%), Gaps = 7/158 (4%)
Frame = +1
Query: 115 ENATSLSLMIDSLLATYDRESPP---DSKIVVNLTLHLRHAN-IRESESTVRILADLQMN 282
+N T + ++D LL YD P D+ V +++ + +++ I +
Sbjct: 62 DNITIFTRILDRLLDGYDNRLRPGLGDAVTEVKTDIYVTSFGPVSDTDMEYTIDVFFRQT 121
Query: 283 WIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSX 453
W D+RL ++ + + ++W PD N + A + R+ +NG++
Sbjct: 122 WHDERLKFDGPMKILPLNNLLASKIWTPDTFFHNGKKSVAHNMTTPNKLLRLVDNGTLLY 181
Query: 454 IKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEM 567
RL I M L+++P D+ C KFGS + + E+
Sbjct: 182 TMRLTIHAECPMHLEDFPMDVHACPLKFGSYAYTTAEV 219
>AF269144-1|AAF99698.1| 467|Homo sapiens GABAA receptor gamma 3
subunit protein.
Length = 467
Score = 49.6 bits (113), Expect = 1e-05
Identities = 39/172 (22%), Positives = 72/172 (41%), Gaps = 7/172 (4%)
Frame = +1
Query: 124 TSLSLMIDSLLATYDRESPPDSKI---VVNLTLHLRHAN-IRESESTVRILADLQMNWID 291
T ++L+++ LL YD++ PD I V+++ +++ + +I W D
Sbjct: 45 TDVTLILNKLLREYDKKLRPDIGIKPTVIDVDIYVNSIGPVSSINMEYQIDIFFAQTWTD 104
Query: 292 KRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSXIKR 462
RL +N+ + +W PD + N+ A R+ N+G + R
Sbjct: 105 SRLRFNSTMKILTLNSNMVGLIWIPDTIFRNSKTAEAHWITTPNQLLRIWNDGKILYTLR 164
Query: 463 LDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDKRIYSMFESGAW 618
L I+ +QL N+P D +C F S + +EM + K + +W
Sbjct: 165 LTINAECQLQLHNFPMDEHSCPLIFSSYGYPKEEMIYRWRKNSVEAADQKSW 216
>AF228458-1|AAF63215.1| 449|Homo sapiens GABAA receptor gamma 3
subunit protein.
Length = 449
Score = 49.6 bits (113), Expect = 1e-05
Identities = 39/172 (22%), Positives = 72/172 (41%), Gaps = 7/172 (4%)
Frame = +1
Query: 124 TSLSLMIDSLLATYDRESPPDSKI---VVNLTLHLRHAN-IRESESTVRILADLQMNWID 291
T ++L+++ LL YD++ PD I V+++ +++ + +I W D
Sbjct: 27 TDVTLILNKLLREYDKKLRPDIGIKPTVIDVDIYVNSIGPVSSINMEYQIDIFFAQTWTD 86
Query: 292 KRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSXIKR 462
RL +N+ + +W PD + N+ A R+ N+G + R
Sbjct: 87 SRLRFNSTMKILTLNSNMVGLIWIPDTIFRNSKTAEAHWITTPNQLLRIWNDGKILYTLR 146
Query: 463 LDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDKRIYSMFESGAW 618
L I+ +QL N+P D +C F S + +EM + K + +W
Sbjct: 147 LTINAECQLQLHNFPMDEHSCPLIFSSYGYPKEEMIYRWRKNSVEAADQKSW 198
>AF166361-1|AAG12455.1| 492|Homo sapiens GABA receptor subunit
alpha 3 protein.
Length = 492
Score = 49.6 bits (113), Expect = 1e-05
Identities = 36/158 (22%), Positives = 69/158 (43%), Gaps = 7/158 (4%)
Frame = +1
Query: 115 ENATSLSLMIDSLLATYDRESPP---DSKIVVNLTLHLRHAN-IRESESTVRILADLQMN 282
+N T + ++D LL YD P D+ V +++ + +++ I +
Sbjct: 62 DNITIFTRILDRLLDGYDNRLRPGLGDAVTEVKTDIYVTSFGPVSDTDMEYTIDVFFRQT 121
Query: 283 WIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSX 453
W D+RL ++ + + ++W PD N + A + R+ +NG++
Sbjct: 122 WHDERLKFDGPMKILPLNNLLASKIWTPDTFFHNGKKSVAHNMTTPNKLLRLVDNGTLLY 181
Query: 454 IKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEM 567
RL I M L+++P D+ C KFGS + + E+
Sbjct: 182 TMRLTIHAECPMHLEDFPMDVHACPLKFGSYAYTTAEV 219
>U77731-2|AAB38273.1| 360|Homo sapiens glycine receptor alpha 2B
subunit protein.
Length = 360
Score = 48.8 bits (111), Expect = 3e-05
Identities = 39/145 (26%), Positives = 64/145 (44%), Gaps = 8/145 (5%)
Frame = +1
Query: 163 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 330
YD P+ K VN+T ++ +I E+ R+ L+ W D RL+++
Sbjct: 58 YDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDSRLAYSEYPDDSL 117
Query: 331 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSXIKRLDISTPISMQLD 498
S + +W+PD+ N D R+S NG V RL ++ M L
Sbjct: 118 DLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLK 177
Query: 499 NWPNDMQTCTFKFGSRMHNSDEMDF 573
N+P D+QTCT + S + +++ F
Sbjct: 178 NFPMDVQTCTMQLESFGYTMNDLIF 202
>CR450343-1|CAG29339.1| 452|Homo sapiens GLRA2 protein.
Length = 452
Score = 48.8 bits (111), Expect = 3e-05
Identities = 39/145 (26%), Positives = 64/145 (44%), Gaps = 8/145 (5%)
Frame = +1
Query: 163 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 330
YD P+ K VN+T ++ +I E+ R+ L+ W D RL+++
Sbjct: 58 YDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDSRLAYSEYPDDSL 117
Query: 331 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSXIKRLDISTPISMQLD 498
S + +W+PD+ N D R+S NG V RL ++ M L
Sbjct: 118 DLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLK 177
Query: 499 NWPNDMQTCTFKFGSRMHNSDEMDF 573
N+P D+QTCT + S + +++ F
Sbjct: 178 NFPMDVQTCTMQLESFGYTMNDLIF 202
>BC111802-1|AAI11803.1| 465|Homo sapiens CHRNG protein protein.
Length = 465
Score = 48.8 bits (111), Expect = 3e-05
Identities = 33/114 (28%), Positives = 51/114 (44%), Gaps = 6/114 (5%)
Frame = +1
Query: 73 PFLLTCAIASAAECENATSLSLMIDSLLATYDRESPPDSKI--VVNLTLHLRHANI---R 237
P LL +A + ++ L+ YD P + VVN++L L N+
Sbjct: 7 PLLLLLLLAVCLGAQGRNQEERLLADLMQNYDPNLRPAERDSDVVNVSLKLTLTNLISLN 66
Query: 238 ESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAAT 396
E E + ++M W D RL W+ ++ G V S +WRPD+VL N + T
Sbjct: 67 EREEALTTNVWIEMQWCDYRLRWDPRDYEGLWVLRVPSTMVWRPDIVLENKSQT 120
>AY437084-1|AAR87843.1| 452|Homo sapiens glycine receptor alpha2
subunit B protein.
Length = 452
Score = 48.8 bits (111), Expect = 3e-05
Identities = 39/145 (26%), Positives = 64/145 (44%), Gaps = 8/145 (5%)
Frame = +1
Query: 163 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 330
YD P+ K VN+T ++ +I E+ R+ L+ W D RL+++
Sbjct: 58 YDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDSRLAYSEYPDDSL 117
Query: 331 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSXIKRLDISTPISMQLD 498
S + +W+PD+ N D R+S NG V RL ++ M L
Sbjct: 118 DLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLK 177
Query: 499 NWPNDMQTCTFKFGSRMHNSDEMDF 573
N+P D+QTCT + S + +++ F
Sbjct: 178 NFPMDVQTCTMQLESFGYTMNDLIF 202
>X52008-1|CAA36257.1| 452|Homo sapiens inhibitory glycine receptor
protein.
Length = 452
Score = 48.4 bits (110), Expect = 3e-05
Identities = 38/145 (26%), Positives = 64/145 (44%), Gaps = 8/145 (5%)
Frame = +1
Query: 163 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 330
YD P+ K VN+T ++ ++ E+ R+ L+ W D RL+++
Sbjct: 58 YDARIRPNFKGPPVNVTCNIFINSFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPDDSL 117
Query: 331 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSXIKRLDISTPISMQLD 498
S + +W+PD+ N D R+S NG V RL ++ M L
Sbjct: 118 DLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLK 177
Query: 499 NWPNDMQTCTFKFGSRMHNSDEMDF 573
N+P D+QTCT + S + +++ F
Sbjct: 178 NFPMDVQTCTMQLESFGYTMNDLIF 202
>U77731-1|AAB38272.1| 360|Homo sapiens glycine receptor alpha 2
subunit protein.
Length = 360
Score = 48.4 bits (110), Expect = 3e-05
Identities = 38/145 (26%), Positives = 64/145 (44%), Gaps = 8/145 (5%)
Frame = +1
Query: 163 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 330
YD P+ K VN+T ++ ++ E+ R+ L+ W D RL+++
Sbjct: 58 YDARIRPNFKGPPVNVTCNIFINSFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPDDSL 117
Query: 331 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSXIKRLDISTPISMQLD 498
S + +W+PD+ N D R+S NG V RL ++ M L
Sbjct: 118 DLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLK 177
Query: 499 NWPNDMQTCTFKFGSRMHNSDEMDF 573
N+P D+QTCT + S + +++ F
Sbjct: 178 NFPMDVQTCTMQLESFGYTMNDLIF 202
>BC032864-1|AAH32864.1| 452|Homo sapiens glycine receptor, alpha 2
protein.
Length = 452
Score = 48.4 bits (110), Expect = 3e-05
Identities = 38/145 (26%), Positives = 64/145 (44%), Gaps = 8/145 (5%)
Frame = +1
Query: 163 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 330
YD P+ K VN+T ++ ++ E+ R+ L+ W D RL+++
Sbjct: 58 YDARIRPNFKGPPVNVTCNIFINSFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPDDSL 117
Query: 331 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSXIKRLDISTPISMQLD 498
S + +W+PD+ N D R+S NG V RL ++ M L
Sbjct: 118 DLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLK 177
Query: 499 NWPNDMQTCTFKFGSRMHNSDEMDF 573
N+P D+QTCT + S + +++ F
Sbjct: 178 NFPMDVQTCTMQLESFGYTMNDLIF 202
>AY437083-1|AAR87842.1| 452|Homo sapiens glycine receptor alpha2
subunit A protein.
Length = 452
Score = 48.4 bits (110), Expect = 3e-05
Identities = 38/145 (26%), Positives = 64/145 (44%), Gaps = 8/145 (5%)
Frame = +1
Query: 163 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 330
YD P+ K VN+T ++ ++ E+ R+ L+ W D RL+++
Sbjct: 58 YDARIRPNFKGPPVNVTCNIFINSFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPDDSL 117
Query: 331 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSXIKRLDISTPISMQLD 498
S + +W+PD+ N D R+S NG V RL ++ M L
Sbjct: 118 DLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLK 177
Query: 499 NWPNDMQTCTFKFGSRMHNSDEMDF 573
N+P D+QTCT + S + +++ F
Sbjct: 178 NFPMDVQTCTMQLESFGYTMNDLIF 202
>AF053495-1|AAC35290.1| 452|Homo sapiens glycine receptor alpha 2
subunit protein.
Length = 452
Score = 48.4 bits (110), Expect = 3e-05
Identities = 38/145 (26%), Positives = 64/145 (44%), Gaps = 8/145 (5%)
Frame = +1
Query: 163 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 330
YD P+ K VN+T ++ ++ E+ R+ L+ W D RL+++
Sbjct: 58 YDARIRPNFKGPPVNVTCNIFINSFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPDDSL 117
Query: 331 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSXIKRLDISTPISMQLD 498
S + +W+PD+ N D R+S NG V RL ++ M L
Sbjct: 118 DLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLK 177
Query: 499 NWPNDMQTCTFKFGSRMHNSDEMDF 573
N+P D+QTCT + S + +++ F
Sbjct: 178 NFPMDVQTCTMQLESFGYTMNDLIF 202
>S81944-1|AAB36480.1| 453|Homo sapiens gamma-aminobutyric acid type
A receptor alpha 6 subunit protein.
Length = 453
Score = 48.0 bits (109), Expect = 4e-05
Identities = 39/166 (23%), Positives = 70/166 (42%), Gaps = 8/166 (4%)
Frame = +1
Query: 127 SLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESESTVRILADLQMNWIDK 294
++S ++D+LL YD P + V +++ + + E + + W D+
Sbjct: 31 NVSRILDNLLEGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTDE 90
Query: 295 RLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRA---RVSNNGSVSXIKRL 465
RL + S + ++W PD N + A + R+ NG++ RL
Sbjct: 91 RLKFGGPTEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTMRL 150
Query: 466 DISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDK-RIYSM 600
I+ M+L N+P D C KFGS + E+ + K +YS+
Sbjct: 151 TINADCPMRLVNFPMDGHACPLKFGSYAYPKSEIIYTWKKGPLYSV 196
>BC099641-1|AAH99641.1| 453|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 6 protein.
Length = 453
Score = 48.0 bits (109), Expect = 4e-05
Identities = 39/166 (23%), Positives = 70/166 (42%), Gaps = 8/166 (4%)
Frame = +1
Query: 127 SLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESESTVRILADLQMNWIDK 294
++S ++D+LL YD P + V +++ + + E + + W D+
Sbjct: 31 NVSRILDNLLEGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTDE 90
Query: 295 RLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRA---RVSNNGSVSXIKRL 465
RL + S + ++W PD N + A + R+ NG++ RL
Sbjct: 91 RLKFGGPTEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTMRL 150
Query: 466 DISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDK-RIYSM 600
I+ M+L N+P D C KFGS + E+ + K +YS+
Sbjct: 151 TINADCPMRLVNFPMDGHACPLKFGSYAYPKSEIIYTWKKGPLYSV 196
>BC099640-1|AAH99640.1| 453|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 6 protein.
Length = 453
Score = 48.0 bits (109), Expect = 4e-05
Identities = 39/166 (23%), Positives = 70/166 (42%), Gaps = 8/166 (4%)
Frame = +1
Query: 127 SLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESESTVRILADLQMNWIDK 294
++S ++D+LL YD P + V +++ + + E + + W D+
Sbjct: 31 NVSRILDNLLEGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTDE 90
Query: 295 RLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRA---RVSNNGSVSXIKRL 465
RL + S + ++W PD N + A + R+ NG++ RL
Sbjct: 91 RLKFGGPTEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTMRL 150
Query: 466 DISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDK-RIYSM 600
I+ M+L N+P D C KFGS + E+ + K +YS+
Sbjct: 151 TINADCPMRLVNFPMDGHACPLKFGSYAYPKSEIIYTWKKGPLYSV 196
>BC096242-1|AAH96242.1| 453|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 6 protein.
Length = 453
Score = 48.0 bits (109), Expect = 4e-05
Identities = 39/166 (23%), Positives = 70/166 (42%), Gaps = 8/166 (4%)
Frame = +1
Query: 127 SLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESESTVRILADLQMNWIDK 294
++S ++D+LL YD P + V +++ + + E + + W D+
Sbjct: 31 NVSRILDNLLEGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTDE 90
Query: 295 RLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRA---RVSNNGSVSXIKRL 465
RL + S + ++W PD N + A + R+ NG++ RL
Sbjct: 91 RLKFGGPTEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTMRL 150
Query: 466 DISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDK-RIYSM 600
I+ M+L N+P D C KFGS + E+ + K +YS+
Sbjct: 151 TINADCPMRLVNFPMDGHACPLKFGSYAYPKSEIIYTWKKGPLYSV 196
>BC096241-1|AAH96241.1| 453|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 6 protein.
Length = 453
Score = 48.0 bits (109), Expect = 4e-05
Identities = 39/166 (23%), Positives = 70/166 (42%), Gaps = 8/166 (4%)
Frame = +1
Query: 127 SLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESESTVRILADLQMNWIDK 294
++S ++D+LL YD P + V +++ + + E + + W D+
Sbjct: 31 NVSRILDNLLEGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTDE 90
Query: 295 RLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRA---RVSNNGSVSXIKRL 465
RL + S + ++W PD N + A + R+ NG++ RL
Sbjct: 91 RLKFGGPTEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTMRL 150
Query: 466 DISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDK-RIYSM 600
I+ M+L N+P D C KFGS + E+ + K +YS+
Sbjct: 151 TINADCPMRLVNFPMDGHACPLKFGSYAYPKSEIIYTWKKGPLYSV 196
>BC022449-1|AAH22449.1| 474|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, beta 1 protein.
Length = 474
Score = 48.0 bits (109), Expect = 4e-05
Identities = 41/180 (22%), Positives = 77/180 (42%), Gaps = 9/180 (5%)
Frame = +1
Query: 61 IILLPFLLT--CAIASAAECENATSLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRH 225
++ P ++T C S E N + + +D LL YD PD + V + + +
Sbjct: 12 LLSFPVMITMVCCAHSTNEPSNMSYVKETVDRLLKGYDIRLRPDFGGPPVDVGMRIDVAS 71
Query: 226 AN-IRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTA 402
+ + E + Q +W DKRLS++ + +++L PD LN +
Sbjct: 72 IDMVSEVNMDYTLTMYFQQSWKDKRLSYSGIPLNLTLDNRVADQLCVPDTYFLNDKKSFV 131
Query: 403 GDYALR---ARVSNNGSVSXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDF 573
++ R+ +G+V R+ + M L +P D Q CT + S + +D+++F
Sbjct: 132 HGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEF 191
>U30461-1|AAB52519.1| 554|Homo sapiens GABAA receptor subunit
alpha4 protein.
Length = 554
Score = 47.2 bits (107), Expect = 8e-05
Identities = 32/119 (26%), Positives = 51/119 (42%), Gaps = 3/119 (2%)
Frame = +1
Query: 238 ESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYAL 417
E E T+ + + WIDKRL ++ + ++W PD N + + +
Sbjct: 90 EMEYTMDVF--FRQTWIDKRLKYDGPIEILRLNNMMVTKVWTPDTFFRNGKKSVSHNMTA 147
Query: 418 RA---RVSNNGSVSXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDK 585
R+ NG++ RL IS M+L ++P D C KFGS + EM + K
Sbjct: 148 PNKLFRIMRNGTILYTMRLTISAECPMRLVDFPMDGHACPLKFGSYAYPKSEMIYTWTK 206
>BC035055-1|AAH35055.1| 554|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 4 protein.
Length = 554
Score = 47.2 bits (107), Expect = 8e-05
Identities = 32/119 (26%), Positives = 51/119 (42%), Gaps = 3/119 (2%)
Frame = +1
Query: 238 ESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYAL 417
E E T+ + + WIDKRL ++ + ++W PD N + + +
Sbjct: 90 EMEYTMDVF--FRQTWIDKRLKYDGPIEILRLNNMMVTKVWTPDTFFRNGKKSVSHNMTA 147
Query: 418 RA---RVSNNGSVSXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDK 585
R+ NG++ RL IS M+L ++P D C KFGS + EM + K
Sbjct: 148 PNKLFRIMRNGTILYTMRLTISAECPMRLVDFPMDGHACPLKFGSYAYPKSEMIYTWTK 206
>BC096083-1|AAH96083.1| 198|Homo sapiens CHRNB4 protein protein.
Length = 198
Score = 46.8 bits (106), Expect = 1e-04
Identities = 33/123 (26%), Positives = 58/123 (47%), Gaps = 8/123 (6%)
Frame = +1
Query: 67 LLPFLLTCAIASAAECENATSLSLMIDSLL--ATYDRESPP--DSKIVVNLTLHLRHA-- 228
L+ F L A+ C A + ++D LL Y+ P S ++++ L L A
Sbjct: 7 LVLFFLV-ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQL 65
Query: 229 -NIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTA 402
++ E E + L+ W D RL+WN+ + G + + ++R+W PD+VL N + T
Sbjct: 66 ISVNEREQIMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNKSLRTG 125
Query: 403 GDY 411
+
Sbjct: 126 STW 128
>BC096081-1|AAH96081.1| 198|Homo sapiens CHRNB4 protein protein.
Length = 198
Score = 46.8 bits (106), Expect = 1e-04
Identities = 33/123 (26%), Positives = 58/123 (47%), Gaps = 8/123 (6%)
Frame = +1
Query: 67 LLPFLLTCAIASAAECENATSLSLMIDSLL--ATYDRESPP--DSKIVVNLTLHLRHA-- 228
L+ F L A+ C A + ++D LL Y+ P S ++++ L L A
Sbjct: 7 LVLFFLV-ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQL 65
Query: 229 -NIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTA 402
++ E E + L+ W D RL+WN+ + G + + ++R+W PD+VL N + T
Sbjct: 66 ISVNEREQIMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNKSLRTG 125
Query: 403 GDY 411
+
Sbjct: 126 STW 128
>U95367-1|AAC51357.1| 440|Homo sapiens GABA-A receptor pi subunit
protein.
Length = 440
Score = 45.6 bits (103), Expect = 2e-04
Identities = 40/164 (24%), Positives = 77/164 (46%), Gaps = 9/164 (5%)
Frame = +1
Query: 109 ECENATSLSLM-IDSLLATYDRESPPD---SKIVVNLTLHLRH-ANIRESESTVRILADL 273
E + LSL ++L A Y++ P+ + + LTL + ++I ES L
Sbjct: 29 EVGRSDKLSLPGFENLTAGYNKFLRPNFGGEPVQIALTLDIASISSISESNMDYTATIYL 88
Query: 274 QMNWIDKRLSWNAGE-WGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNG 441
+ W+D+RL + + + LV E LW PD ++ + + + + R+ +NG
Sbjct: 89 RQRWMDQRLVFEGNKSFTLDARLV--EFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNG 146
Query: 442 SVSXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDF 573
+V R+ + +M L +P D QTC + S ++ ++++F
Sbjct: 147 TVLYALRITTTVACNMDLSKYPMDTQTCKLQLESWGYDGNDVEF 190
>BC109211-1|AAI09212.1| 632|Homo sapiens gamma-aminobutyric acid
(GABA) receptor, theta protein.
Length = 632
Score = 45.6 bits (103), Expect = 2e-04
Identities = 35/145 (24%), Positives = 59/145 (40%), Gaps = 7/145 (4%)
Frame = +1
Query: 112 CENATSLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESESTVRILADLQM 279
C N + ++D +L+ YD P+ + + V +++++ I E I
Sbjct: 53 CANEAVVQKILDRVLSRYDVRLRPNFGGAPVPVRISIYVTSIEQISEMNMDYTITMFFHQ 112
Query: 280 NWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSN---NGSVS 450
W D RL++ + E+LW PD LN+ D + RV +G+V
Sbjct: 113 TWKDSRLAYYETTLNLTLDYRMHEKLWVPDCYFLNSKDAFVHDVTVENRVFQLHPDGTVR 172
Query: 451 XIKRLDISTPISMQLDNWPNDMQTC 525
RL + S+ L +P D Q C
Sbjct: 173 YGIRLTTTAACSLDLHKFPMDKQAC 197
>BC109210-1|AAI09211.1| 632|Homo sapiens gamma-aminobutyric acid
(GABA) receptor, theta protein.
Length = 632
Score = 45.6 bits (103), Expect = 2e-04
Identities = 35/145 (24%), Positives = 59/145 (40%), Gaps = 7/145 (4%)
Frame = +1
Query: 112 CENATSLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESESTVRILADLQM 279
C N + ++D +L+ YD P+ + + V +++++ I E I
Sbjct: 53 CANEAVVQKILDRVLSRYDVRLRPNFGGAPVPVRISIYVTSIEQISEMNMDYTITMFFHQ 112
Query: 280 NWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSN---NGSVS 450
W D RL++ + E+LW PD LN+ D + RV +G+V
Sbjct: 113 TWKDSRLAYYETTLNLTLDYRMHEKLWVPDCYFLNSKDAFVHDVTVENRVFQLHPDGTVR 172
Query: 451 XIKRLDISTPISMQLDNWPNDMQTC 525
RL + S+ L +P D Q C
Sbjct: 173 YGIRLTTTAACSLDLHKFPMDKQAC 197
>BC109106-1|AAI09107.1| 440|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, pi protein.
Length = 440
Score = 45.6 bits (103), Expect = 2e-04
Identities = 40/164 (24%), Positives = 77/164 (46%), Gaps = 9/164 (5%)
Frame = +1
Query: 109 ECENATSLSLM-IDSLLATYDRESPPD---SKIVVNLTLHLRH-ANIRESESTVRILADL 273
E + LSL ++L A Y++ P+ + + LTL + ++I ES L
Sbjct: 29 EVGRSDKLSLPGFENLTAGYNKFLRPNFGGEPVQIALTLDIASISSISESNMDYTATIYL 88
Query: 274 QMNWIDKRLSWNAGE-WGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNG 441
+ W+D+RL + + + LV E LW PD ++ + + + + R+ +NG
Sbjct: 89 RQRWMDQRLVFEGNKSFTLDARLV--EFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNG 146
Query: 442 SVSXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDF 573
+V R+ + +M L +P D QTC + S ++ ++++F
Sbjct: 147 TVLYALRITTTVACNMDLSKYPMDTQTCKLQLESWGYDGNDVEF 190
>BC109105-1|AAI09106.1| 440|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, pi protein.
Length = 440
Score = 45.6 bits (103), Expect = 2e-04
Identities = 40/164 (24%), Positives = 77/164 (46%), Gaps = 9/164 (5%)
Frame = +1
Query: 109 ECENATSLSLM-IDSLLATYDRESPPD---SKIVVNLTLHLRH-ANIRESESTVRILADL 273
E + LSL ++L A Y++ P+ + + LTL + ++I ES L
Sbjct: 29 EVGRSDKLSLPGFENLTAGYNKFLRPNFGGEPVQIALTLDIASISSISESNMDYTATIYL 88
Query: 274 QMNWIDKRLSWNAGE-WGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNG 441
+ W+D+RL + + + LV E LW PD ++ + + + + R+ +NG
Sbjct: 89 RQRWMDQRLVFEGNKSFTLDARLV--EFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNG 146
Query: 442 SVSXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDF 573
+V R+ + +M L +P D QTC + S ++ ++++F
Sbjct: 147 TVLYALRITTTVACNMDLSKYPMDTQTCKLQLESWGYDGNDVEF 190
>BC074865-1|AAH74865.1| 440|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, pi protein.
Length = 440
Score = 45.6 bits (103), Expect = 2e-04
Identities = 40/164 (24%), Positives = 77/164 (46%), Gaps = 9/164 (5%)
Frame = +1
Query: 109 ECENATSLSLM-IDSLLATYDRESPPD---SKIVVNLTLHLRH-ANIRESESTVRILADL 273
E + LSL ++L A Y++ P+ + + LTL + ++I ES L
Sbjct: 29 EVGRSDKLSLPGFENLTAGYNKFLRPNFGGEPVQIALTLDIASISSISESNMDYTATIYL 88
Query: 274 QMNWIDKRLSWNAGE-WGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNG 441
+ W+D+RL + + + LV E LW PD ++ + + + + R+ +NG
Sbjct: 89 RQRWMDQRLVFEGNKSFTLDARLV--EFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNG 146
Query: 442 SVSXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDF 573
+V R+ + +M L +P D QTC + S ++ ++++F
Sbjct: 147 TVLYALRITTTVACNMDLSKYPMDTQTCKLQLESWGYDGNDVEF 190
>BC074810-1|AAH74810.1| 440|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, pi protein.
Length = 440
Score = 45.6 bits (103), Expect = 2e-04
Identities = 40/164 (24%), Positives = 77/164 (46%), Gaps = 9/164 (5%)
Frame = +1
Query: 109 ECENATSLSLM-IDSLLATYDRESPPD---SKIVVNLTLHLRH-ANIRESESTVRILADL 273
E + LSL ++L A Y++ P+ + + LTL + ++I ES L
Sbjct: 29 EVGRSDKLSLPGFENLTAGYNKFLRPNFGGEPVQIALTLDIASISSISESNMDYTATIYL 88
Query: 274 QMNWIDKRLSWNAGE-WGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNG 441
+ W+D+RL + + + LV E LW PD ++ + + + + R+ +NG
Sbjct: 89 RQRWMDQRLVFEGNKSFTLDARLV--EFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNG 146
Query: 442 SVSXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDF 573
+V R+ + +M L +P D QTC + S ++ ++++F
Sbjct: 147 TVLYALRITTTVACNMDLSKYPMDTQTCKLQLESWGYDGNDVEF 190
>BC033801-1|AAH33801.1| 452|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, delta protein.
Length = 452
Score = 45.6 bits (103), Expect = 2e-04
Identities = 38/149 (25%), Positives = 63/149 (42%), Gaps = 7/149 (4%)
Frame = +1
Query: 142 IDSLLATYDRESPPD-SKIVVNLTLHLRHANI---RESESTVRILADLQMNWIDKRLSWN 309
+D L+A Y R P VN+ L L A+I E+ + L +W D RLS+N
Sbjct: 44 LDGLIAGYARNFRPGIGGPPVNVALALEVASIDHISEANMEYTMTVFLHQSWRDSRLSYN 103
Query: 310 AGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSXIKRLDISTP 480
++LW PD ++NA + D + R+ +G + R+ +
Sbjct: 104 HTNETLGLDSRFVDKLWLPDTFIVNAKSAWFHDVTVENKLIRLQPDGVILYSIRITSTVA 163
Query: 481 ISMQLDNWPNDMQTCTFKFGSRMHNSDEM 567
M L +P D Q C S ++S+++
Sbjct: 164 CDMDLAKYPMDEQECMLDLESYGYSSEDI 192
>AL391845-4|CAI15436.1| 452|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, delta protein.
Length = 452
Score = 45.6 bits (103), Expect = 2e-04
Identities = 38/149 (25%), Positives = 63/149 (42%), Gaps = 7/149 (4%)
Frame = +1
Query: 142 IDSLLATYDRESPPD-SKIVVNLTLHLRHANI---RESESTVRILADLQMNWIDKRLSWN 309
+D L+A Y R P VN+ L L A+I E+ + L +W D RLS+N
Sbjct: 44 LDGLIAGYARNFRPGIGGPPVNVALALEVASIDHISEANMEYTMTVFLHQSWRDSRLSYN 103
Query: 310 AGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSXIKRLDISTP 480
++LW PD ++NA + D + R+ +G + R+ +
Sbjct: 104 HTNETLGLDSRFVDKLWLPDTFIVNAKSAWFHDVTVENKLIRLQPDGVILYSIRITSTVA 163
Query: 481 ISMQLDNWPNDMQTCTFKFGSRMHNSDEM 567
M L +P D Q C S ++S+++
Sbjct: 164 CDMDLAKYPMDEQECMLDLESYGYSSEDI 192
>AF189259-1|AAF70380.1| 632|Homo sapiens GABA-A receptor theta
subunit protein.
Length = 632
Score = 45.6 bits (103), Expect = 2e-04
Identities = 35/145 (24%), Positives = 59/145 (40%), Gaps = 7/145 (4%)
Frame = +1
Query: 112 CENATSLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESESTVRILADLQM 279
C N + ++D +L+ YD P+ + + V +++++ I E I
Sbjct: 53 CANEAVVQKILDRVLSRYDVRLRPNFGGAPVPVRISIYVTSIEQISEMNMDYTITMFFHQ 112
Query: 280 NWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSN---NGSVS 450
W D RL++ + E+LW PD LN+ D + RV +G+V
Sbjct: 113 TWKDSRLAYYETTLNLTLDYRMHEKLWVPDCYFLNSKDAFVHDVTVENRVFQLHPDGTVR 172
Query: 451 XIKRLDISTPISMQLDNWPNDMQTC 525
RL + S+ L +P D Q C
Sbjct: 173 YGIRLTTTAACSLDLHKFPMDKQAC 197
>AF144648-1|AAD51172.1| 627|Homo sapiens GABA-A receptor theta
protein.
Length = 627
Score = 45.6 bits (103), Expect = 2e-04
Identities = 35/145 (24%), Positives = 59/145 (40%), Gaps = 7/145 (4%)
Frame = +1
Query: 112 CENATSLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESESTVRILADLQM 279
C N + ++D +L+ YD P+ + + V +++++ I E I
Sbjct: 48 CANEAVVQKILDRVLSRYDVRLRPNFGGAPVPVRISIYVTSIEQISEMNMDYTITMFFHQ 107
Query: 280 NWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSN---NGSVS 450
W D RL++ + E+LW PD LN+ D + RV +G+V
Sbjct: 108 TWKDSRLAYYETTLNLTLDYRMHEKLWVPDCYFLNSKDAFVHDVTVENRVFQLHPDGTVR 167
Query: 451 XIKRLDISTPISMQLDNWPNDMQTC 525
RL + S+ L +P D Q C
Sbjct: 168 YGIRLTTTAACSLDLHKFPMDKQAC 192
>AF016917-1|AAB70007.1| 452|Homo sapiens GABA-A receptor delta
subunit protein.
Length = 452
Score = 45.6 bits (103), Expect = 2e-04
Identities = 38/149 (25%), Positives = 63/149 (42%), Gaps = 7/149 (4%)
Frame = +1
Query: 142 IDSLLATYDRESPPD-SKIVVNLTLHLRHANI---RESESTVRILADLQMNWIDKRLSWN 309
+D L+A Y R P VN+ L L A+I E+ + L +W D RLS+N
Sbjct: 44 LDGLIAGYARNFRPGIGGPPVNVALALEVASIDHISEANMEYTMTVFLHQSWRDSRLSYN 103
Query: 310 AGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSXIKRLDISTP 480
++LW PD ++NA + D + R+ +G + R+ +
Sbjct: 104 HTNETLGLDSRFVDKLWLPDTFIVNAKSAWFHDVTVENKLIRLQPDGVILYSIRITSTVA 163
Query: 481 ISMQLDNWPNDMQTCTFKFGSRMHNSDEM 567
M L +P D Q C S ++S+++
Sbjct: 164 CDMDLAKYPMDEQECMLDLESYGYSSEDI 192
>AF009702-1|AAC24194.1| 440|Homo sapiens GABA-A receptor pi subunit
protein.
Length = 440
Score = 45.6 bits (103), Expect = 2e-04
Identities = 40/164 (24%), Positives = 77/164 (46%), Gaps = 9/164 (5%)
Frame = +1
Query: 109 ECENATSLSLM-IDSLLATYDRESPPD---SKIVVNLTLHLRH-ANIRESESTVRILADL 273
E + LSL ++L A Y++ P+ + + LTL + ++I ES L
Sbjct: 29 EVGRSDKLSLPGFENLTAGYNKFLRPNFGGEPVQIALTLDIASISSISESNMDYTATIYL 88
Query: 274 QMNWIDKRLSWNAGE-WGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNG 441
+ W+D+RL + + + LV E LW PD ++ + + + + R+ +NG
Sbjct: 89 RQRWMDQRLVFEGNKSFTLDARLV--EFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNG 146
Query: 442 SVSXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDF 573
+V R+ + +M L +P D QTC + S ++ ++++F
Sbjct: 147 TVLYALRITTTVACNMDLSKYPMDTQTCKLQLESWGYDGNDVEF 190
>U93917-1|AAC39917.1| 449|Homo sapiens glycine receptor alpha 3
subunit protein.
Length = 449
Score = 44.8 bits (101), Expect = 4e-04
Identities = 45/181 (24%), Positives = 76/181 (41%), Gaps = 11/181 (6%)
Frame = +1
Query: 64 ILLPFLLTCAIASAAECENATSLSLMIDSLLAT---YDRESPPDSK-IVVNLTLHL---R 222
+LL + T SA S S +D L+ YD P+ K VN+T ++
Sbjct: 21 LLLSLVATKETDSARSRSAPMSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINS 80
Query: 223 HANIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERLWRPDVVLLNAAATT 399
+I E+ R+ L+ W D RL+++ S + +W+PD+ N
Sbjct: 81 FGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGAN 140
Query: 400 AGDYALR---ARVSNNGSVSXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 570
+ R+ NG+V RL ++ M L N+P D+QTC + S + +++
Sbjct: 141 FHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFPMDVQTCIMQLESFGYTMNDLI 200
Query: 571 F 573
F
Sbjct: 201 F 201
>BC114947-1|AAI14948.1| 457|Homo sapiens GLRA1 protein protein.
Length = 457
Score = 44.8 bits (101), Expect = 4e-04
Identities = 46/195 (23%), Positives = 85/195 (43%), Gaps = 17/195 (8%)
Frame = +1
Query: 40 HKMSTTYIILLPFLLTCAIASAAECENATSL------SLMIDSLLAT---YDRESPPDSK 192
+ +T + L ++ ++A++ E E A S S +D L+ YD P+ K
Sbjct: 2 YSFNTLRLYLWETIVFFSLAASKEAEAARSAPKPMSPSDFLDKLMGRTSGYDARIRPNFK 61
Query: 193 -IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERL 357
VN++ ++ +I E+ R+ L+ W D RL++N S + +
Sbjct: 62 GPPVNVSCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYNEYPDDSLDLDPSMLDSI 121
Query: 358 WRPDVVLLNAAATTAGDYALR---ARVSNNGSVSXIKRLDISTPISMQLDNWPNDMQTCT 528
W+PD+ N + R+S NG+V R+ ++ M L N+P D+QTC
Sbjct: 122 WKPDLFFANEKGAHFHEITTDNKLLRISRNGNVLYSIRITLTLACPMDLKNFPMDVQTCI 181
Query: 529 FKFGSRMHNSDEMDF 573
+ S + +++ F
Sbjct: 182 MQLESFGYTMNDLIF 196
>BC074980-1|AAH74980.1| 449|Homo sapiens glycine receptor, alpha 1
(startle disease/hyperekplexia) protein.
Length = 449
Score = 44.8 bits (101), Expect = 4e-04
Identities = 46/195 (23%), Positives = 85/195 (43%), Gaps = 17/195 (8%)
Frame = +1
Query: 40 HKMSTTYIILLPFLLTCAIASAAECENATSL------SLMIDSLLAT---YDRESPPDSK 192
+ +T + L ++ ++A++ E E A S S +D L+ YD P+ K
Sbjct: 2 YSFNTLRLYLWETIVFFSLAASKEAEAARSAPKPMSPSDFLDKLMGRTSGYDARIRPNFK 61
Query: 193 -IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERL 357
VN++ ++ +I E+ R+ L+ W D RL++N S + +
Sbjct: 62 GPPVNVSCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYNEYPDDSLDLDPSMLDSI 121
Query: 358 WRPDVVLLNAAATTAGDYALR---ARVSNNGSVSXIKRLDISTPISMQLDNWPNDMQTCT 528
W+PD+ N + R+S NG+V R+ ++ M L N+P D+QTC
Sbjct: 122 WKPDLFFANEKGAHFHEITTDNKLLRISRNGNVLYSIRITLTLACPMDLKNFPMDVQTCI 181
Query: 529 FKFGSRMHNSDEMDF 573
+ S + +++ F
Sbjct: 182 MQLESFGYTMNDLIF 196
>BC036086-1|AAH36086.1| 464|Homo sapiens glycine receptor, alpha 3
protein.
Length = 464
Score = 44.8 bits (101), Expect = 4e-04
Identities = 45/181 (24%), Positives = 76/181 (41%), Gaps = 11/181 (6%)
Frame = +1
Query: 64 ILLPFLLTCAIASAAECENATSLSLMIDSLLAT---YDRESPPDSK-IVVNLTLHL---R 222
+LL + T SA S S +D L+ YD P+ K VN+T ++
Sbjct: 21 LLLSLVATKETDSARSRSAPMSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINS 80
Query: 223 HANIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERLWRPDVVLLNAAATT 399
+I E+ R+ L+ W D RL+++ S + +W+PD+ N
Sbjct: 81 FGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGAN 140
Query: 400 AGDYALR---ARVSNNGSVSXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 570
+ R+ NG+V RL ++ M L N+P D+QTC + S + +++
Sbjct: 141 FHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFPMDVQTCIMQLESFGYTMNDLI 200
Query: 571 F 573
F
Sbjct: 201 F 201
>AF017724-1|AAC39919.1| 465|Homo sapiens glycine receptor alpha 3
subunit protein.
Length = 465
Score = 44.8 bits (101), Expect = 4e-04
Identities = 45/181 (24%), Positives = 76/181 (41%), Gaps = 11/181 (6%)
Frame = +1
Query: 64 ILLPFLLTCAIASAAECENATSLSLMIDSLLAT---YDRESPPDSK-IVVNLTLHL---R 222
+LL + T SA S S +D L+ YD P+ K VN+T ++
Sbjct: 21 LLLSLVATKETDSARSRSAPMSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINS 80
Query: 223 HANIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERLWRPDVVLLNAAATT 399
+I E+ R+ L+ W D RL+++ S + +W+PD+ N
Sbjct: 81 FGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGAN 140
Query: 400 AGDYALR---ARVSNNGSVSXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 570
+ R+ NG+V RL ++ M L N+P D+QTC + S + +++
Sbjct: 141 FHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFPMDVQTCIMQLESFGYTMNDLI 200
Query: 571 F 573
F
Sbjct: 201 F 201
>X52009-1|CAA36258.1| 449|Homo sapiens inhibitory glycine receptor
protein.
Length = 449
Score = 44.4 bits (100), Expect = 5e-04
Identities = 46/195 (23%), Positives = 85/195 (43%), Gaps = 17/195 (8%)
Frame = +1
Query: 40 HKMSTTYIILLPFLLTCAIASAAECENATSL------SLMIDSLLAT---YDRESPPDSK 192
+ +T + L ++ ++A++ E E A S S +D L+ YD P+ K
Sbjct: 2 YSFNTLRLYLSGAIVFFSLAASKEAEAARSATKPMSPSDFLDKLMGRTSGYDARIRPNFK 61
Query: 193 -IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERL 357
VN++ ++ +I E+ R+ L+ W D RL++N S + +
Sbjct: 62 GPPVNVSCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYNEYPDDSLDLDPSMLDSI 121
Query: 358 WRPDVVLLNAAATTAGDYALR---ARVSNNGSVSXIKRLDISTPISMQLDNWPNDMQTCT 528
W+PD+ N + R+S NG+V R+ ++ M L N+P D+QTC
Sbjct: 122 WKPDLFFANEKGAHFHEITTDNKLLRISRNGNVLYSIRITLTLACPMDLKNFPMDVQTCI 181
Query: 529 FKFGSRMHNSDEMDF 573
+ S + +++ F
Sbjct: 182 MQLESFGYTMNDLIF 196
>BC074795-1|AAH74795.1| 467|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, gamma 2 protein.
Length = 467
Score = 44.4 bits (100), Expect = 5e-04
Identities = 37/172 (21%), Positives = 74/172 (43%), Gaps = 9/172 (5%)
Frame = +1
Query: 130 LSLMIDSLLATYDRESPPDSKI---VVNLTLHLRH---ANIRESESTVRILADLQMNWID 291
+++++++LL YD + PD + +++ +++ N E T+ I W D
Sbjct: 66 VTVILNNLLEGYDNKLRPDIGVKPTLIHTDMYVNSIGPVNAINMEYTIDIF--FAQTWYD 123
Query: 292 KRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYAL---RARVSNNGSVSXIKR 462
+RL +N+ ++W PD N+ A R+ N+G V R
Sbjct: 124 RRLKFNSTIKVLRLNSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYTLR 183
Query: 463 LDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDKRIYSMFESGAW 618
L I +QL N+P D +C +F S + +E+ + + + ++ +W
Sbjct: 184 LTIDAECQLQLHNFPMDEHSCPLEFSSYGYPREEIVYQWKRSSVEVGDTRSW 235
>BC069348-1|AAH69348.1| 467|Homo sapiens gamma-aminobutyric acid A
receptor, gamma 2, isoform 2 precursor protein.
Length = 467
Score = 44.4 bits (100), Expect = 5e-04
Identities = 37/172 (21%), Positives = 74/172 (43%), Gaps = 9/172 (5%)
Frame = +1
Query: 130 LSLMIDSLLATYDRESPPDSKI---VVNLTLHLRH---ANIRESESTVRILADLQMNWID 291
+++++++LL YD + PD + +++ +++ N E T+ I W D
Sbjct: 66 VTVILNNLLEGYDNKLRPDIGVKPTLIHTDMYVNSIGPVNAINMEYTIDIF--FAQTWYD 123
Query: 292 KRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYAL---RARVSNNGSVSXIKR 462
+RL +N+ ++W PD N+ A R+ N+G V R
Sbjct: 124 RRLKFNSTIKVLRLNSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYTLR 183
Query: 463 LDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDKRIYSMFESGAW 618
L I +QL N+P D +C +F S + +E+ + + + ++ +W
Sbjct: 184 LTIDAECQLQLHNFPMDEHSCPLEFSSYGYPREEIVYQWKRSSVEVGDTRSW 235
>BC059389-1|AAH59389.1| 475|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, gamma 2 protein.
Length = 475
Score = 44.4 bits (100), Expect = 5e-04
Identities = 37/172 (21%), Positives = 74/172 (43%), Gaps = 9/172 (5%)
Frame = +1
Query: 130 LSLMIDSLLATYDRESPPDSKI---VVNLTLHLRH---ANIRESESTVRILADLQMNWID 291
+++++++LL YD + PD + +++ +++ N E T+ I W D
Sbjct: 66 VTVILNNLLEGYDNKLRPDIGVKPTLIHTDMYVNSIGPVNAINMEYTIDIF--FAQTWYD 123
Query: 292 KRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYAL---RARVSNNGSVSXIKR 462
+RL +N+ ++W PD N+ A R+ N+G V R
Sbjct: 124 RRLKFNSTIKVLRLNSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYTLR 183
Query: 463 LDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDKRIYSMFESGAW 618
L I +QL N+P D +C +F S + +E+ + + + ++ +W
Sbjct: 184 LTIDAECQLQLHNFPMDEHSCPLEFSSYGYPREEIVYQWKRSSVEVGDTRSW 235
>AF165124-1|AAD50273.1| 467|Homo sapiens gamma-aminobutyric acid A
receptor gamma 2 protein.
Length = 467
Score = 44.4 bits (100), Expect = 5e-04
Identities = 37/172 (21%), Positives = 74/172 (43%), Gaps = 9/172 (5%)
Frame = +1
Query: 130 LSLMIDSLLATYDRESPPDSKI---VVNLTLHLRH---ANIRESESTVRILADLQMNWID 291
+++++++LL YD + PD + +++ +++ N E T+ I W D
Sbjct: 66 VTVILNNLLEGYDNKLRPDIGVKPTLIHTDMYVNSIGPVNAINMEYTIDIF--FAQTWYD 123
Query: 292 KRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYAL---RARVSNNGSVSXIKR 462
+RL +N+ ++W PD N+ A R+ N+G V R
Sbjct: 124 RRLKFNSTIKVLRLNSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYTLR 183
Query: 463 LDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDKRIYSMFESGAW 618
L I +QL N+P D +C +F S + +E+ + + + ++ +W
Sbjct: 184 LTIDAECQLQLHNFPMDEHSCPLEFSSYGYPREEIVYQWKRSSVEVGDTRSW 235
>BC031087-1|AAH31087.1| 465|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, gamma 1 protein.
Length = 465
Score = 44.0 bits (99), Expect = 7e-04
Identities = 39/172 (22%), Positives = 73/172 (42%), Gaps = 9/172 (5%)
Frame = +1
Query: 130 LSLMIDSLLATYDRESPPDSKI---VVNLTLHLRHANIRES---ESTVRILADLQMNWID 291
++ +++SLL YD + PD + V+ +++ + E T+ I+ W D
Sbjct: 64 ITQILNSLLQGYDNKLRPDIGVRPTVIETDVYVNSIGPVDPINMEYTIDII--FAQTWFD 121
Query: 292 KRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSXIKR 462
RL +N+ ++W PD N+ + A R+ N+G V R
Sbjct: 122 SRLKFNSTMKVLMLNSNMVGKIWIPDTFFRNSRKSDAHWITTPNRLLRIWNDGRVLYTLR 181
Query: 463 LDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDKRIYSMFESGAW 618
L I+ +QL N+P D +C +F S + +E+++ K + + W
Sbjct: 182 LTINAECYLQLHNFPMDEHSCPLEFSSYGYPKNEIEYKWKKPSVEVADPKYW 233
>X15376-1|CAA33437.1| 467|Homo sapiens GABA-A receptor gamma 2
subunit protein.
Length = 467
Score = 43.6 bits (98), Expect = 0.001
Identities = 39/172 (22%), Positives = 76/172 (44%), Gaps = 9/172 (5%)
Frame = +1
Query: 130 LSLMIDSLLATYDRESPPDSKI---VVNLTLHLRH---ANIRESESTVRILADLQMNWID 291
+++++++LL YD + PD + +++ +++ N E T+ I QM W D
Sbjct: 66 VTVILNNLLEGYDNKLRPDIGVKPTLIHTDMYVNSIGPVNAINMEYTIDIFF-AQM-WYD 123
Query: 292 KRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYAL---RARVSNNGSVSXIKR 462
+RL +N+ ++W PD N+ A R+ N+G V R
Sbjct: 124 RRLKFNSTIKVLRLNSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYSLR 183
Query: 463 LDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDKRIYSMFESGAW 618
L I +QL N+P D +C +F S + +E+ + + + ++ +W
Sbjct: 184 LTIDAECQLQLHNFPMDEHSCPLEFSSYGYPREEIVYQWKRSSVEVGDTRSW 235
>Z93848-1|CAI41994.1| 376|Homo sapiens glycine receptor, alpha 4
protein.
Length = 376
Score = 42.3 bits (95), Expect = 0.002
Identities = 37/145 (25%), Positives = 62/145 (42%), Gaps = 8/145 (5%)
Frame = +1
Query: 163 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 330
YD P+ K VN+T ++ ++I ++ R+ L+ W D RLS+
Sbjct: 17 YDARIRPNFKGPPVNVTCNIFINSFSSITKTTMDYRVNVFLRQQWNDPRLSYREYPDDSL 76
Query: 331 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSXIKRLDISTPISMQLD 498
S + +W+PD+ N + R+ NG+V RL + M L
Sbjct: 77 DLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLILSCLMDLK 136
Query: 499 NWPNDMQTCTFKFGSRMHNSDEMDF 573
N+P D+QTCT + S + ++ F
Sbjct: 137 NFPMDIQTCTMQLESFGYTMKDLVF 161
>AL049610-1|CAI42158.1| 376|Homo sapiens glycine receptor, alpha 4
protein.
Length = 376
Score = 42.3 bits (95), Expect = 0.002
Identities = 37/145 (25%), Positives = 62/145 (42%), Gaps = 8/145 (5%)
Frame = +1
Query: 163 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 330
YD P+ K VN+T ++ ++I ++ R+ L+ W D RLS+
Sbjct: 17 YDARIRPNFKGPPVNVTCNIFINSFSSITKTTMDYRVNVFLRQQWNDPRLSYREYPDDSL 76
Query: 331 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSXIKRLDISTPISMQLD 498
S + +W+PD+ N + R+ NG+V RL + M L
Sbjct: 77 DLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLILSCLMDLK 136
Query: 499 NWPNDMQTCTFKFGSRMHNSDEMDF 573
N+P D+QTCT + S + ++ F
Sbjct: 137 NFPMDIQTCTMQLESFGYTMKDLVF 161
>BC114967-1|AAI14968.1| 366|Homo sapiens GLRA1 protein protein.
Length = 366
Score = 41.1 bits (92), Expect = 0.005
Identities = 28/110 (25%), Positives = 49/110 (44%), Gaps = 4/110 (3%)
Frame = +1
Query: 256 RILADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERLWRPDVVLLNAAATTAGDYALR---A 423
R+ L+ W D RL++N S + +W+PD+ N +
Sbjct: 4 RVNIFLRQQWNDPRLAYNEYPDDSLDLDPSMLDSIWKPDLFFANEKGAHFHEITTDNKLL 63
Query: 424 RVSNNGSVSXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDF 573
R+S NG+V R+ ++ M L N+P D+QTC + S + +++ F
Sbjct: 64 RISRNGNVLYSIRITLTLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIF 113
>AB209359-1|BAD92596.1| 533|Homo sapiens cholinergic receptor,
nicotinic, alpha polypeptide 4 precursor variant
protein.
Length = 533
Score = 36.7 bits (81), Expect = 0.11
Identities = 24/91 (26%), Positives = 41/91 (45%), Gaps = 3/91 (3%)
Frame = +1
Query: 355 LWRPDVVLLNAAATTAGDYALRARVSNNGSVSXIKRLDISTPISMQLDNWPNDMQTCTFK 534
LW +A A + +A + ++G V + S+ + +P D Q CT K
Sbjct: 25 LWLCCCTFTSADGDFAVTHLTKAHLFHDGRVQWTPPAIYKSSCSIDVTFFPFDQQNCTMK 84
Query: 535 FGSRMHNSDEMDFV-IDKRI--YSMFESGAW 618
FGS ++ ++D V + R+ +ESG W
Sbjct: 85 FGSWTYDKAKIDLVNMHSRVDQLDFWESGEW 115
>BC096291-1|AAH96291.1| 556|Homo sapiens CHRNA4 protein protein.
Length = 556
Score = 35.9 bits (79), Expect = 0.19
Identities = 23/79 (29%), Positives = 40/79 (50%), Gaps = 7/79 (8%)
Frame = +1
Query: 403 GDYAL----RARVSNNGSVSXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 570
GD+A+ +A + ++G V + S+ + +P D Q CT KFGS ++ ++D
Sbjct: 60 GDFAVTHLTKAHLFHDGRVQWTPPAIYKSSCSIDVTFFPFDQQNCTMKFGSWTYDKAKID 119
Query: 571 FV-IDKRI--YSMFESGAW 618
V + R+ +ESG W
Sbjct: 120 LVNMHSRVDQLDFWESGEW 138
>AY049075-1|AAL06603.1| 514|Homo sapiens dynein heavy chain
protein.
Length = 514
Score = 32.3 bits (70), Expect = 2.3
Identities = 17/39 (43%), Positives = 23/39 (58%), Gaps = 1/39 (2%)
Frame = +1
Query: 511 DMQTCTFKFGSRMHNSDEMDFVIDKRIYS-MFESGAWGC 624
DM C K+ + SD+MDF RI+ + +SGAWGC
Sbjct: 37 DMGRCLGKYVVVFNCSDQMDFRGLGRIFKGLAQSGAWGC 75
>Y00285-1|CAA68395.1| 2491|Homo sapiens protein ( Human mRNA for
insuline-like growth factor II receptor. ).
Length = 2491
Score = 30.3 bits (65), Expect = 9.4
Identities = 21/77 (27%), Positives = 34/77 (44%), Gaps = 3/77 (3%)
Frame = +2
Query: 425 VYLITAPSPX*S--AWTLALQFLCS*TIGPTTCRLARSSSVLGCTIVTKWIS*LT-KEYT 595
VY +P P S ++ + F+C GPT + S CT+ W + L ++ T
Sbjct: 1591 VYKDGSPCPSKSGLSYKSVISFVCRPEAGPTNRPMLISLDKQTCTLFFSWHTPLACEQAT 1650
Query: 596 VCSSQERGDVTDLSSAV 646
CS + + DLS +
Sbjct: 1651 ECSVRNGSSIVDLSPLI 1667
>J03528-1|AAA59866.1| 2491|Homo sapiens mannose 6-phosphate receptor
protein.
Length = 2491
Score = 30.3 bits (65), Expect = 9.4
Identities = 21/77 (27%), Positives = 34/77 (44%), Gaps = 3/77 (3%)
Frame = +2
Query: 425 VYLITAPSPX*S--AWTLALQFLCS*TIGPTTCRLARSSSVLGCTIVTKWIS*LT-KEYT 595
VY +P P S ++ + F+C GPT + S CT+ W + L ++ T
Sbjct: 1591 VYKDGSPCPSKSGLSYKSVISFVCRPEAGPTNRPMLISLDKQTCTLFFSWHTPLACEQAT 1650
Query: 596 VCSSQERGDVTDLSSAV 646
CS + + DLS +
Sbjct: 1651 ECSVRNGSSIVDLSPLI 1667
>AY293855-1|AAP37954.1| 2491|Homo sapiens insulin-like growth factor 2
receptor protein.
Length = 2491
Score = 30.3 bits (65), Expect = 9.4
Identities = 21/77 (27%), Positives = 34/77 (44%), Gaps = 3/77 (3%)
Frame = +2
Query: 425 VYLITAPSPX*S--AWTLALQFLCS*TIGPTTCRLARSSSVLGCTIVTKWIS*LT-KEYT 595
VY +P P S ++ + F+C GPT + S CT+ W + L ++ T
Sbjct: 1591 VYKDGSPCPSKSGLSYKSVISFVCRPEAGPTNRPMLISLDKQTCTLFFSWHTPLACEQAT 1650
Query: 596 VCSSQERGDVTDLSSAV 646
CS + + DLS +
Sbjct: 1651 ECSVRNGSSIVDLSPLI 1667
>AF109291-1|AAF16870.1| 2491|Homo sapiens insulin-like growth factor 2
receptor protein.
Length = 2491
Score = 30.3 bits (65), Expect = 9.4
Identities = 21/77 (27%), Positives = 34/77 (44%), Gaps = 3/77 (3%)
Frame = +2
Query: 425 VYLITAPSPX*S--AWTLALQFLCS*TIGPTTCRLARSSSVLGCTIVTKWIS*LT-KEYT 595
VY +P P S ++ + F+C GPT + S CT+ W + L ++ T
Sbjct: 1591 VYKDGSPCPSKSGLSYKSVISFVCRPEAGPTNRPMLISLDKQTCTLFFSWHTPLACEQAT 1650
Query: 596 VCSSQERGDVTDLSSAV 646
CS + + DLS +
Sbjct: 1651 ECSVRNGSSIVDLSPLI 1667
>AB209668-1|BAD92905.1| 2414|Homo sapiens Insulin-like growth factor 2
receptor variant protein.
Length = 2414
Score = 30.3 bits (65), Expect = 9.4
Identities = 21/77 (27%), Positives = 34/77 (44%), Gaps = 3/77 (3%)
Frame = +2
Query: 425 VYLITAPSPX*S--AWTLALQFLCS*TIGPTTCRLARSSSVLGCTIVTKWIS*LT-KEYT 595
VY +P P S ++ + F+C GPT + S CT+ W + L ++ T
Sbjct: 1514 VYKDGSPCPSKSGLSYKSVISFVCRPEAGPTNRPMLISLDKQTCTLFFSWHTPLACEQAT 1573
Query: 596 VCSSQERGDVTDLSSAV 646
CS + + DLS +
Sbjct: 1574 ECSVRNGSSIVDLSPLI 1590
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 119,367,991
Number of Sequences: 237096
Number of extensions: 2726404
Number of successful extensions: 6973
Number of sequences better than 10.0: 184
Number of HSP's better than 10.0 without gapping: 6355
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 6833
length of database: 76,859,062
effective HSP length: 89
effective length of database: 55,757,518
effective search space used: 10984231046
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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