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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= BmNP01_FL5_M18
         (916 letters)

Database: human 
           237,096 sequences; 76,859,062 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

X14830-1|CAA32939.1|  501|Homo sapiens protein ( Human mRNA for ...    36   0.27 
BC023553-1|AAH23553.1|  501|Homo sapiens cholinergic receptor, n...    36   0.27 
BC011371-1|AAH11371.1|  501|Homo sapiens cholinergic receptor, n...    36   0.27 
Y08416-1|CAA69693.1|  498|Homo sapiens nicotinic acetylcholine r...    34   0.83 
Y00762-1|CAA68731.1|  457|Homo sapiens protein ( Human mRNA for ...    34   0.83 
X02502-1|CAA26344.1|  457|Homo sapiens acetylcholine receptor pr...    34   0.83 
U62439-1|AAB40117.1|  498|Homo sapiens nicotinic acetylcholine r...    34   0.83 
U48861-1|AAA92123.1|  498|Homo sapiens beta 4 nicotinic acetylch...    34   0.83 
S77094-1|AAD14247.1|  457|Homo sapiens nicotinic acetylcholine r...    34   0.83 
BC096083-1|AAH96083.1|  198|Homo sapiens CHRNB4 protein protein.       34   0.83 
BC096082-1|AAH96082.1|  498|Homo sapiens cholinergic receptor, n...    34   0.83 
BC096081-1|AAH96081.1|  198|Homo sapiens CHRNB4 protein protein.       34   0.83 
BC096080-1|AAH96080.1|  498|Homo sapiens cholinergic receptor, n...    34   0.83 
BC006314-1|AAH06314.1|  269|Homo sapiens CHRNA1 protein protein.       34   0.83 
AF306329-1|AAL02062.1|  498|Homo sapiens neuronal nicotinic acet...    34   0.83 
AC018890-1|AAY14687.1|  457|Homo sapiens unknown protein.              34   0.83 
AJ306454-1|CAC34819.1|  497|Homo sapiens neuronal nicotinic acet...    33   1.1  
Y16281-1|CAA76154.1|  529|Homo sapiens nicotinic acetylcholine r...    33   1.9  
U62431-1|AAB40109.1|  529|Homo sapiens nicotinic acetylcholine r...    33   1.9  
X68275-1|CAA48336.1|  451|Homo sapiens nicotinic receptor beta 4...    32   3.3  

>X14830-1|CAA32939.1|  501|Homo sapiens protein ( Human mRNA for
           muscle acetylcholine receptor beta-subunit. ).
          Length = 501

 Score = 35.5 bits (78), Expect = 0.27
 Identities = 22/67 (32%), Positives = 37/67 (55%), Gaps = 2/67 (2%)
 Frame = +2

Query: 164 KIVVNLTL-HLRHANIRESESTVRIQADLQMNXIDKRLSXNXGEW-GCSTWLVSSERLWM 337
           ++ V L L  L   N ++ E + ++  DL+    D RLS +  E  G  +  +++E +W+
Sbjct: 53  RVSVGLILAQLISLNEKDEEMSTKVYLDLEWT--DYRLSWDPAEHDGIDSLRITAESVWL 110

Query: 338 PDXVLLN 358
           PD VLLN
Sbjct: 111 PDVVLLN 117


>BC023553-1|AAH23553.1|  501|Homo sapiens cholinergic receptor,
           nicotinic, beta 1 (muscle) protein.
          Length = 501

 Score = 35.5 bits (78), Expect = 0.27
 Identities = 22/67 (32%), Positives = 37/67 (55%), Gaps = 2/67 (2%)
 Frame = +2

Query: 164 KIVVNLTL-HLRHANIRESESTVRIQADLQMNXIDKRLSXNXGEW-GCSTWLVSSERLWM 337
           ++ V L L  L   N ++ E + ++  DL+    D RLS +  E  G  +  +++E +W+
Sbjct: 53  RVSVGLILAQLISLNEKDEEMSTKVYLDLEWT--DYRLSWDPAEHDGIDSLRITAESVWL 110

Query: 338 PDXVLLN 358
           PD VLLN
Sbjct: 111 PDVVLLN 117


>BC011371-1|AAH11371.1|  501|Homo sapiens cholinergic receptor,
           nicotinic, beta 1 (muscle) protein.
          Length = 501

 Score = 35.5 bits (78), Expect = 0.27
 Identities = 22/67 (32%), Positives = 37/67 (55%), Gaps = 2/67 (2%)
 Frame = +2

Query: 164 KIVVNLTL-HLRHANIRESESTVRIQADLQMNXIDKRLSXNXGEW-GCSTWLVSSERLWM 337
           ++ V L L  L   N ++ E + ++  DL+    D RLS +  E  G  +  +++E +W+
Sbjct: 53  RVSVGLILAQLISLNEKDEEMSTKVYLDLEWT--DYRLSWDPAEHDGIDSLRITAESVWL 110

Query: 338 PDXVLLN 358
           PD VLLN
Sbjct: 111 PDVVLLN 117


>Y08416-1|CAA69693.1|  498|Homo sapiens nicotinic acetylcholine
           receptor beta4 subunit precursor protein.
          Length = 498

 Score = 33.9 bits (74), Expect = 0.83
 Identities = 21/79 (26%), Positives = 37/79 (46%), Gaps = 4/79 (5%)
 Frame = +2

Query: 149 PPPXSKIVVNLTLHLRHA---NIRESESTVRIQADLQMNXIDKRLSXNXGEW-GCSTWLV 316
           P   S  ++++ L L  A   ++ E E  +     L+    D RL+ N   + G +   +
Sbjct: 46  PATSSSQLISIKLQLSLAQLISVNEREQIMTTNVWLKQEWTDYRLTWNSSRYEGVNILRI 105

Query: 317 SSERLWMPDXVLLNXXXXT 373
            ++R+W+PD VL N    T
Sbjct: 106 PAKRIWLPDIVLYNNADGT 124


>Y00762-1|CAA68731.1|  457|Homo sapiens protein ( Human mRNA for
           muscle acetylcholine receptor alpha-subunit. ).
          Length = 457

 Score = 33.9 bits (74), Expect = 0.83
 Identities = 22/90 (24%), Positives = 38/90 (42%), Gaps = 1/90 (1%)
 Frame = +2

Query: 164 KIVVNLTLHLRHANIRESESTVRIQADLQMNXIDKRLSXNXGEWGCSTWL-VSSERLWMP 340
           ++ V L L ++  N+ E    V     L+   +D  L  N  ++G    + + SE++W P
Sbjct: 50  EVTVGLQL-IQLINVDEVNQIVTTNVRLKQQWVDYNLKWNPDDYGGVKKIHIPSEKIWRP 108

Query: 341 DXVLLNXXXXTXGGLRSPXPRYLXTGSXSW 430
           D VL N        ++        TG  +W
Sbjct: 109 DLVLYNNADGDFAIVKFTKVLLQYTGHITW 138


>X02502-1|CAA26344.1|  457|Homo sapiens acetylcholine receptor
           protein.
          Length = 457

 Score = 33.9 bits (74), Expect = 0.83
 Identities = 22/90 (24%), Positives = 38/90 (42%), Gaps = 1/90 (1%)
 Frame = +2

Query: 164 KIVVNLTLHLRHANIRESESTVRIQADLQMNXIDKRLSXNXGEWGCSTWL-VSSERLWMP 340
           ++ V L L ++  N+ E    V     L+   +D  L  N  ++G    + + SE++W P
Sbjct: 50  EVTVGLQL-IQLINVDEVNQIVTTNVRLKQQWVDYNLKWNPDDYGGVKKIHIPSEKIWRP 108

Query: 341 DXVLLNXXXXTXGGLRSPXPRYLXTGSXSW 430
           D VL N        ++        TG  +W
Sbjct: 109 DLVLYNNADGDFAIVKFTKVLLQYTGHITW 138


>U62439-1|AAB40117.1|  498|Homo sapiens nicotinic acetylcholine
           receptor beta4 subunit precursor protein.
          Length = 498

 Score = 33.9 bits (74), Expect = 0.83
 Identities = 21/79 (26%), Positives = 37/79 (46%), Gaps = 4/79 (5%)
 Frame = +2

Query: 149 PPPXSKIVVNLTLHLRHA---NIRESESTVRIQADLQMNXIDKRLSXNXGEW-GCSTWLV 316
           P   S  ++++ L L  A   ++ E E  +     L+    D RL+ N   + G +   +
Sbjct: 46  PATSSSQLISIKLQLSLAQLISVNEREQIMTTNVWLKQEWTDYRLTWNSSRYEGVNILRI 105

Query: 317 SSERLWMPDXVLLNXXXXT 373
            ++R+W+PD VL N    T
Sbjct: 106 PAKRIWLPDIVLYNNADGT 124


>U48861-1|AAA92123.1|  498|Homo sapiens beta 4 nicotinic
           acetylcholine receptor subunit protein.
          Length = 498

 Score = 33.9 bits (74), Expect = 0.83
 Identities = 21/79 (26%), Positives = 37/79 (46%), Gaps = 4/79 (5%)
 Frame = +2

Query: 149 PPPXSKIVVNLTLHLRHA---NIRESESTVRIQADLQMNXIDKRLSXNXGEW-GCSTWLV 316
           P   S  ++++ L L  A   ++ E E  +     L+    D RL+ N   + G +   +
Sbjct: 46  PATSSSQLISIKLQLSLAQLISVNEREQIMTTNVWLKQEWTDYRLTWNSSRYEGVNILRI 105

Query: 317 SSERLWMPDXVLLNXXXXT 373
            ++R+W+PD VL N    T
Sbjct: 106 PAKRIWLPDIVLYNNADGT 124


>S77094-1|AAD14247.1|  457|Homo sapiens nicotinic acetylcholine
           receptor alpha subunit|AChR protein.
          Length = 457

 Score = 33.9 bits (74), Expect = 0.83
 Identities = 22/90 (24%), Positives = 38/90 (42%), Gaps = 1/90 (1%)
 Frame = +2

Query: 164 KIVVNLTLHLRHANIRESESTVRIQADLQMNXIDKRLSXNXGEWGCSTWL-VSSERLWMP 340
           ++ V L L ++  N+ E    V     L+   +D  L  N  ++G    + + SE++W P
Sbjct: 50  EVTVGLQL-IQLINVDEVNQIVTTNVRLKQQWVDYNLKWNPDDYGGVKKIHIPSEKIWRP 108

Query: 341 DXVLLNXXXXTXGGLRSPXPRYLXTGSXSW 430
           D VL N        ++        TG  +W
Sbjct: 109 DLVLYNNADGDFAIVKFTKVLLQYTGHITW 138


>BC096083-1|AAH96083.1|  198|Homo sapiens CHRNB4 protein protein.
          Length = 198

 Score = 33.9 bits (74), Expect = 0.83
 Identities = 21/79 (26%), Positives = 37/79 (46%), Gaps = 4/79 (5%)
 Frame = +2

Query: 149 PPPXSKIVVNLTLHLRHA---NIRESESTVRIQADLQMNXIDKRLSXNXGEW-GCSTWLV 316
           P   S  ++++ L L  A   ++ E E  +     L+    D RL+ N   + G +   +
Sbjct: 46  PATSSSQLISIKLQLSLAQLISVNEREQIMTTNVWLKQEWTDYRLTWNSSRYEGVNILRI 105

Query: 317 SSERLWMPDXVLLNXXXXT 373
            ++R+W+PD VL N    T
Sbjct: 106 PAKRIWLPDIVLYNKSLRT 124


>BC096082-1|AAH96082.1|  498|Homo sapiens cholinergic receptor,
           nicotinic, beta 4 protein.
          Length = 498

 Score = 33.9 bits (74), Expect = 0.83
 Identities = 21/79 (26%), Positives = 37/79 (46%), Gaps = 4/79 (5%)
 Frame = +2

Query: 149 PPPXSKIVVNLTLHLRHA---NIRESESTVRIQADLQMNXIDKRLSXNXGEW-GCSTWLV 316
           P   S  ++++ L L  A   ++ E E  +     L+    D RL+ N   + G +   +
Sbjct: 46  PATSSSQLISIKLQLSLAQLISVNEREQIMTTNVWLKQEWTDYRLTWNSSRYEGVNILRI 105

Query: 317 SSERLWMPDXVLLNXXXXT 373
            ++R+W+PD VL N    T
Sbjct: 106 PAKRIWLPDIVLYNNADGT 124


>BC096081-1|AAH96081.1|  198|Homo sapiens CHRNB4 protein protein.
          Length = 198

 Score = 33.9 bits (74), Expect = 0.83
 Identities = 21/79 (26%), Positives = 37/79 (46%), Gaps = 4/79 (5%)
 Frame = +2

Query: 149 PPPXSKIVVNLTLHLRHA---NIRESESTVRIQADLQMNXIDKRLSXNXGEW-GCSTWLV 316
           P   S  ++++ L L  A   ++ E E  +     L+    D RL+ N   + G +   +
Sbjct: 46  PATSSSQLISIKLQLSLAQLISVNEREQIMTTNVWLKQEWTDYRLTWNSSRYEGVNILRI 105

Query: 317 SSERLWMPDXVLLNXXXXT 373
            ++R+W+PD VL N    T
Sbjct: 106 PAKRIWLPDIVLYNKSLRT 124


>BC096080-1|AAH96080.1|  498|Homo sapiens cholinergic receptor,
           nicotinic, beta 4 protein.
          Length = 498

 Score = 33.9 bits (74), Expect = 0.83
 Identities = 21/79 (26%), Positives = 37/79 (46%), Gaps = 4/79 (5%)
 Frame = +2

Query: 149 PPPXSKIVVNLTLHLRHA---NIRESESTVRIQADLQMNXIDKRLSXNXGEW-GCSTWLV 316
           P   S  ++++ L L  A   ++ E E  +     L+    D RL+ N   + G +   +
Sbjct: 46  PATSSSQLISIKLQLSLAQLISVNEREQIMTTNVWLKQEWTDYRLTWNSSRYEGVNILRI 105

Query: 317 SSERLWMPDXVLLNXXXXT 373
            ++R+W+PD VL N    T
Sbjct: 106 PAKRIWLPDIVLYNNADGT 124


>BC006314-1|AAH06314.1|  269|Homo sapiens CHRNA1 protein protein.
          Length = 269

 Score = 33.9 bits (74), Expect = 0.83
 Identities = 22/90 (24%), Positives = 38/90 (42%), Gaps = 1/90 (1%)
 Frame = +2

Query: 164 KIVVNLTLHLRHANIRESESTVRIQADLQMNXIDKRLSXNXGEWGCSTWL-VSSERLWMP 340
           ++ V L L ++  N+ E    V     L+   +D  L  N  ++G    + + SE++W P
Sbjct: 50  EVTVGLQL-IQLINVDEVNQIVTTNVRLKQQWVDYNLKWNPDDYGGVKKIHIPSEKIWRP 108

Query: 341 DXVLLNXXXXTXGGLRSPXPRYLXTGSXSW 430
           D VL N        ++        TG  +W
Sbjct: 109 DLVLYNNADGDFAIVKFTKVLLQYTGHITW 138


>AF306329-1|AAL02062.1|  498|Homo sapiens neuronal nicotinic
           acetylcholine receptor beta 4 subunit protein.
          Length = 498

 Score = 33.9 bits (74), Expect = 0.83
 Identities = 21/79 (26%), Positives = 37/79 (46%), Gaps = 4/79 (5%)
 Frame = +2

Query: 149 PPPXSKIVVNLTLHLRHA---NIRESESTVRIQADLQMNXIDKRLSXNXGEW-GCSTWLV 316
           P   S  ++++ L L  A   ++ E E  +     L+    D RL+ N   + G +   +
Sbjct: 46  PATSSSQLISIKLQLSLAQLISVNEREQIMTTNVWLKQEWTDYRLTWNSSRYEGVNILRI 105

Query: 317 SSERLWMPDXVLLNXXXXT 373
            ++R+W+PD VL N    T
Sbjct: 106 PAKRIWLPDIVLYNNADGT 124


>AC018890-1|AAY14687.1|  457|Homo sapiens unknown protein.
          Length = 457

 Score = 33.9 bits (74), Expect = 0.83
 Identities = 22/90 (24%), Positives = 38/90 (42%), Gaps = 1/90 (1%)
 Frame = +2

Query: 164 KIVVNLTLHLRHANIRESESTVRIQADLQMNXIDKRLSXNXGEWGCSTWL-VSSERLWMP 340
           ++ V L L ++  N+ E    V     L+   +D  L  N  ++G    + + SE++W P
Sbjct: 50  EVTVGLQL-IQLINVDEVNQIVTTNVRLKQQWVDYNLKWNPDDYGGVKKIHIPSEKIWRP 108

Query: 341 DXVLLNXXXXTXGGLRSPXPRYLXTGSXSW 430
           D VL N        ++        TG  +W
Sbjct: 109 DLVLYNNADGDFAIVKFTKVLLQYTGHITW 138


>AJ306454-1|CAC34819.1|  497|Homo sapiens neuronal nicotinic
           acetylcholine receptor beta-4 subunit protein.
          Length = 497

 Score = 33.5 bits (73), Expect = 1.1
 Identities = 20/74 (27%), Positives = 36/74 (48%), Gaps = 4/74 (5%)
 Frame = +2

Query: 149 PPPXSKIVVNLTLHLRHA---NIRESESTVRIQADLQMNXIDKRLSXNXGEW-GCSTWLV 316
           P   S  ++++ L L  A   ++ E E  +     L+    D RL+ N   + G +   +
Sbjct: 46  PATSSSQLISIKLQLSLAQLISVNEREQIMTTNVWLKQEWTDYRLTWNSSRYEGVNILRI 105

Query: 317 SSERLWMPDXVLLN 358
            ++R+W+PD VL N
Sbjct: 106 PAKRIWLPDIVLYN 119


>Y16281-1|CAA76154.1|  529|Homo sapiens nicotinic acetylcholine
           receptor alpha2 subunit precursor protein.
          Length = 529

 Score = 32.7 bits (71), Expect = 1.9
 Identities = 23/96 (23%), Positives = 36/96 (37%), Gaps = 2/96 (2%)
 Frame = +2

Query: 149 PPPXSKIVVNLTLHLRHA-NIRESESTVRIQADLQMNXIDKRLSXNXGEWGCSTWL-VSS 322
           P     ++V   L +    ++ E    +     L+    D +L  N  ++G  T L V S
Sbjct: 78  PNTSDVVIVRFGLSIAQLIDVDEKNQMMTTNVWLKQEWSDYKLRWNPADFGNITSLRVPS 137

Query: 323 ERLWMPDXVLLNXXXXTXGGLRSPXPRYLXTGSXSW 430
           E +W+PD VL N                  TG+  W
Sbjct: 138 EMIWIPDIVLYNNADGEFAVTHMTKAHLFSTGTVHW 173


>U62431-1|AAB40109.1|  529|Homo sapiens nicotinic acetylcholine
           receptor alpha2 subunit precursor protein.
          Length = 529

 Score = 32.7 bits (71), Expect = 1.9
 Identities = 23/96 (23%), Positives = 36/96 (37%), Gaps = 2/96 (2%)
 Frame = +2

Query: 149 PPPXSKIVVNLTLHLRHA-NIRESESTVRIQADLQMNXIDKRLSXNXGEWGCSTWL-VSS 322
           P     ++V   L +    ++ E    +     L+    D +L  N  ++G  T L V S
Sbjct: 78  PNTSDVVIVRFGLSIAQLIDVDEKNQMMTTNVWLKQEWSDYKLRWNPADFGNITSLRVPS 137

Query: 323 ERLWMPDXVLLNXXXXTXGGLRSPXPRYLXTGSXSW 430
           E +W+PD VL N                  TG+  W
Sbjct: 138 EMIWIPDIVLYNNADGEFAVTHMTKAHLFSTGTVHW 173


>X68275-1|CAA48336.1|  451|Homo sapiens nicotinic receptor beta 4
           subunit protein.
          Length = 451

 Score = 31.9 bits (69), Expect = 3.3
 Identities = 19/71 (26%), Positives = 33/71 (46%), Gaps = 2/71 (2%)
 Frame = +2

Query: 167 IVVNLTLHLRHA-NIRESESTVRIQADLQMNXIDKRLSXNXGEW-GCSTWLVSSERLWMP 340
           I + L L L    ++ E +  +     L+    D RL+ N   + G +   + ++R+W+P
Sbjct: 7   ISIKLQLSLAQLISVNERDEIMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLP 66

Query: 341 DXVLLNXXXXT 373
           D VL N    T
Sbjct: 67  DIVLYNNADGT 77


  Database: human
    Posted date:  Oct 23, 2007  1:18 PM
  Number of letters in database: 76,859,062
  Number of sequences in database:  237,096
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 76,757,826
Number of Sequences: 237096
Number of extensions: 1333015
Number of successful extensions: 3506
Number of sequences better than 10.0: 20
Number of HSP's better than 10.0 without gapping: 2888
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3473
length of database: 76,859,062
effective HSP length: 90
effective length of database: 55,520,422
effective search space used: 11881370308
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

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