Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BmNP01_FL5_J11
(903 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
AJ306454-1|CAC34819.1| 497|Homo sapiens neuronal nicotinic acet... 74 6e-13
Y08416-1|CAA69693.1| 498|Homo sapiens nicotinic acetylcholine r... 72 3e-12
U62439-1|AAB40117.1| 498|Homo sapiens nicotinic acetylcholine r... 72 3e-12
U48861-1|AAA92123.1| 498|Homo sapiens beta 4 nicotinic acetylch... 72 3e-12
BC096082-1|AAH96082.1| 498|Homo sapiens cholinergic receptor, n... 72 3e-12
BC096080-1|AAH96080.1| 498|Homo sapiens cholinergic receptor, n... 72 3e-12
AF306329-1|AAL02062.1| 498|Homo sapiens neuronal nicotinic acet... 72 3e-12
BT006897-1|AAP35543.1| 505|Homo sapiens cholinergic receptor, n... 69 2e-11
BT006646-1|AAP35292.1| 489|Homo sapiens cholinergic receptor, n... 69 2e-11
BC006114-1|AAH06114.1| 489|Homo sapiens CHRNA3 protein protein. 69 2e-11
BC002996-1|AAH02996.1| 505|Homo sapiens cholinergic receptor, n... 69 2e-11
BC001642-1|AAH01642.1| 505|Homo sapiens cholinergic receptor, n... 69 2e-11
BC000513-1|AAH00513.1| 505|Homo sapiens cholinergic receptor, n... 69 2e-11
AF385584-1|AAK68110.1| 489|Homo sapiens nicotinic cholinergic r... 69 2e-11
Y08419-1|CAA69696.1| 468|Homo sapiens nicotinic acetylcholine r... 68 4e-11
Y08418-1|CAA69695.1| 503|Homo sapiens nicotinic acetylcholine r... 68 4e-11
U62434-1|AAB40112.1| 468|Homo sapiens nicotinic acetylcholine r... 68 4e-11
U62432-1|AAB40110.1| 504|Homo sapiens nicotinic acetylcholine r... 68 4e-11
M37981-1|AAA59942.1| 503|Homo sapiens neuronal nicotinic acetyl... 68 4e-11
BC098443-1|AAH98443.1| 504|Homo sapiens cholinergic receptor, n... 68 4e-11
BC033639-1|AAH33639.1| 468|Homo sapiens cholinergic receptor, n... 68 4e-11
AJ306481-1|CAC34820.1| 468|Homo sapiens neuronal nicotinic acet... 68 4e-11
AJ007783-1|CAA07682.1| 504|Homo sapiens nicotinic acetylcholine... 68 4e-11
X68275-1|CAA48336.1| 451|Homo sapiens nicotinic receptor beta 4... 68 5e-11
Y08417-1|CAA69694.1| 458|Homo sapiens nicotinic acetylcholine r... 67 7e-11
X67513-1|CAA47851.1| 423|Homo sapiens nicotinic acetylcholine ... 67 7e-11
U62438-1|AAB40116.1| 458|Homo sapiens nicotinic acetylcholine r... 67 7e-11
BC069788-1|AAH69788.1| 458|Homo sapiens cholinergic receptor, n... 67 7e-11
BC069703-1|AAH69703.1| 458|Homo sapiens cholinergic receptor, n... 67 7e-11
BC069681-1|AAH69681.1| 458|Homo sapiens cholinergic receptor, n... 67 7e-11
AF140765-1|AAD33063.1| 458|Homo sapiens neuronal acetylcholine ... 67 7e-11
M83712-1|AAA58357.1| 468|Homo sapiens nicotinic receptor alpha ... 67 9e-11
Y16282-1|CAA76155.1| 494|Homo sapiens nicotinic acetylcholine r... 66 1e-10
X53559-1|CAA37625.1| 474|Homo sapiens neuronal nicotinic acetyl... 66 1e-10
U62435-1|AAB40113.1| 494|Homo sapiens nicotinic acetylcholine r... 66 1e-10
BC014456-1|AAH14456.1| 494|Homo sapiens cholinergic receptor, n... 66 1e-10
AB079251-1|BAC06855.1| 494|Homo sapiens Nicotinic acetylcholine... 66 1e-10
M86383-1|AAC84176.1| 502|Homo sapiens nicotinic acetylcholine r... 66 2e-10
X01715-1|CAA25861.1| 520|Homo sapiens acetylcholine receptor ga... 65 3e-10
AC092165-3|AAY24103.1| 520|Homo sapiens unknown protein. 65 3e-10
Y16281-1|CAA76154.1| 529|Homo sapiens nicotinic acetylcholine r... 64 5e-10
U62431-1|AAB40109.1| 529|Homo sapiens nicotinic acetylcholine r... 64 5e-10
X14830-1|CAA32939.1| 501|Homo sapiens protein ( Human mRNA for ... 64 7e-10
BC011371-1|AAH11371.1| 501|Homo sapiens cholinergic receptor, n... 64 7e-10
X66403-1|CAA47030.1| 493|Homo sapiens acetylcholine receptor ep... 64 9e-10
AF105999-1|AAD24503.1| 493|Homo sapiens acetylcholine receptor ... 64 9e-10
Y08421-1|CAA69698.1| 627|Homo sapiens nicotinic acetylcholine r... 63 2e-09
X89741-1|CAA61893.1| 627|Homo sapiens neuronal acetylcholine re... 63 2e-09
U62433-1|AAB40111.1| 627|Homo sapiens nicotinic acetylcholine r... 63 2e-09
L35901-1|AAA64743.1| 627|Homo sapiens nicotinic acetylcholine r... 63 2e-09
DQ093071-1|AAY88737.1| 627|Homo sapiens cholinergic receptor, n... 63 2e-09
BC096290-1|AAH96290.1| 627|Homo sapiens cholinergic receptor, n... 63 2e-09
BC023553-1|AAH23553.1| 501|Homo sapiens cholinergic receptor, n... 63 2e-09
X87629-1|CAA60959.1| 602|Homo sapiens nicotinic acetylcholine r... 62 2e-09
AJ001935-1|CAA05108.1| 504|Homo sapiens CHRNB2 protein. 62 2e-09
Y08415-1|CAA69692.1| 502|Homo sapiens nicotinic acetylcholine r... 62 3e-09
Y00762-1|CAA68731.1| 457|Homo sapiens protein ( Human mRNA for ... 62 3e-09
X53179-1|CAA37320.1| 502|Homo sapiens precursor peptide (AA -25... 62 3e-09
X02502-1|CAA26344.1| 457|Homo sapiens acetylcholine receptor pr... 62 3e-09
U62437-1|AAB40115.1| 502|Homo sapiens nicotinic acetylcholine r... 62 3e-09
S77094-1|AAD14247.1| 457|Homo sapiens nicotinic acetylcholine r... 62 3e-09
BC075041-1|AAH75041.1| 502|Homo sapiens cholinergic receptor, n... 62 3e-09
BC075040-1|AAH75040.1| 502|Homo sapiens cholinergic receptor, n... 62 3e-09
BC006314-1|AAH06314.1| 269|Homo sapiens CHRNA1 protein protein. 62 3e-09
AL592078-3|CAI16184.1| 502|Homo sapiens cholinergic receptor, n... 62 3e-09
AF077186-1|AAD45422.1| 502|Homo sapiens neuronal nicotinic acet... 62 3e-09
AC018890-1|AAY14687.1| 457|Homo sapiens unknown protein. 62 3e-09
AJ295237-1|CAC16144.1| 450|Homo sapiens neuronal nicotinic acet... 58 4e-08
AJ278118-1|CAC20435.1| 450|Homo sapiens neuronal nicotinic acet... 58 4e-08
AF327367-1|AAK14333.1| 450|Homo sapiens nicotinic acetylcholine... 58 4e-08
AF199235-1|AAG00795.2| 450|Homo sapiens nicotinic acetylcholine... 58 4e-08
DQ644022-1|ABG35128.1| 456|Homo sapiens 5-HT3 receptor subunit ... 57 8e-08
BC131799-1|AAI31800.1| 447|Homo sapiens 5-hydroxytryptamine (se... 57 8e-08
BC101185-1|AAI01186.1| 374|Homo sapiens HTR3E protein protein. 57 8e-08
BC101183-1|AAI01184.1| 471|Homo sapiens 5-hydroxytryptamine (se... 57 8e-08
BC101182-1|AAI01183.1| 471|Homo sapiens 5-hydroxytryptamine (se... 57 8e-08
AY159813-1|AAO38167.2| 471|Homo sapiens 5-hydroxytryptamine ser... 57 8e-08
X55019-1|CAA38759.1| 517|Homo sapiens acetylcholine receptor de... 57 1e-07
BC093925-1|AAH93925.1| 517|Homo sapiens cholinergic receptor, n... 57 1e-07
BC093923-1|AAH93923.1| 517|Homo sapiens cholinergic receptor, n... 57 1e-07
AF459285-1|AAL66182.1| 447|Homo sapiens 5-hydroxytryptamine rec... 57 1e-07
AC092165-2|AAY24102.1| 517|Homo sapiens unknown protein. 57 1e-07
S77554-1|AAB33983.1| 474|Homo sapiens GABAA receptor beta 2 sub... 56 2e-07
S77553-1|AAB33982.1| 512|Homo sapiens GABAA receptor beta 2 sub... 56 2e-07
S67368-1|AAB29370.1| 474|Homo sapiens gamma-aminobutyric acid A... 56 2e-07
BC113575-1|AAI13576.1| 479|Homo sapiens cholinergic receptor, n... 56 2e-07
BC113549-1|AAI13550.1| 479|Homo sapiens cholinergic receptor, n... 56 2e-07
BC105639-1|AAI05640.1| 474|Homo sapiens GABRB2 protein protein. 56 2e-07
BC099719-1|AAH99719.1| 474|Homo sapiens GABRB2 protein protein. 56 2e-07
BC099705-1|AAH99705.1| 474|Homo sapiens GABRB2 protein protein. 56 2e-07
AY349353-1|AAQ93477.1| 456|Homo sapiens 5-HT3c1 serotonin recep... 56 2e-07
AY349352-1|AAQ93476.1| 441|Homo sapiens 5-HT3c1 serotonin recep... 56 2e-07
AY123244-1|AAM74523.1| 479|Homo sapiens nicotinic acetylcholine... 56 2e-07
AJ243342-1|CAB65091.1| 479|Homo sapiens nicotinic acetylcholine... 56 2e-07
AF227732-1|AAF61920.1| 470|Homo sapiens nicotinic acetylcholine... 56 2e-07
AC118275-1|AAY40986.1| 479|Homo sapiens unknown protein. 56 2e-07
Z23141-1|CAA80672.1| 479|Homo sapiens cholinergic receptor, nic... 55 4e-07
Y08420-1|CAA69697.1| 502|Homo sapiens nicotinic acetylcholine r... 55 4e-07
X70297-1|CAA49778.1| 502|Homo sapiens neuronal nicotinic acetyl... 55 4e-07
U62436-1|AAB40114.1| 502|Homo sapiens nicotinic acetylcholine r... 55 4e-07
AJ586911-1|CAE52911.1| 502|Homo sapiens nicotinic acetylcholine... 55 4e-07
BC111802-1|AAI11803.1| 465|Homo sapiens CHRNG protein protein. 54 5e-07
BC110597-1|AAI10598.1| 411|Homo sapiens ligand-gated ion channe... 54 5e-07
AF512521-1|AAO20969.1| 411|Homo sapiens ligand-gated ion channe... 54 5e-07
AB223030-1|BAE19924.1| 411|Homo sapiens ligand-gated ion-channe... 54 7e-07
L08485-1|AAA58490.1| 462|Homo sapiens GABA-benzodiazepine recep... 54 9e-07
BT009830-1|AAP88832.1| 462|Homo sapiens gamma-aminobutyric acid... 54 9e-07
BC113422-1|AAI13423.1| 462|Homo sapiens gamma-aminobutyric acid... 54 9e-07
BC111979-1|AAI11980.1| 462|Homo sapiens gamma-aminobutyric acid... 54 9e-07
U40583-1|AAA83561.1| 502|Homo sapiens alpha 7 neuronal nicotini... 53 1e-06
AF385585-1|AAK68111.1| 502|Homo sapiens nicotinic cholinergic r... 53 1e-06
S82612-1|AAB37533.2| 478|Homo sapiens 5-hydroxytryptamine type ... 52 2e-06
M59216-1|AAA35862.1| 474|Homo sapiens gamma-aminobutyric acid r... 52 2e-06
AJ003080-1|CAA05853.1| 238|Homo sapiens serotonin receptor prot... 52 2e-06
X14767-1|CAA32875.1| 474|Homo sapiens GABA-A receptor beta 1 su... 52 4e-06
D49394-1|BAA08387.1| 478|Homo sapiens serotonin 5-HT3 receptor ... 52 4e-06
BT007204-1|AAP35868.1| 484|Homo sapiens 5-hydroxytryptamine (se... 52 4e-06
BC004453-1|AAH04453.2| 478|Homo sapiens 5-hydroxytryptamine (se... 52 4e-06
BC002354-1|AAH02354.1| 478|Homo sapiens 5-hydroxytryptamine (se... 52 4e-06
AJ005205-1|CAA06442.3| 478|Homo sapiens serotonin 3 receptor pr... 52 4e-06
AJ003079-1|CAA05852.1| 478|Homo sapiens 5-hydroxytryptamine3 re... 52 4e-06
AJ003078-1|CAA05851.1| 510|Homo sapiens serotonin receptor prot... 52 4e-06
AF498984-1|AAM21131.1| 478|Homo sapiens 5-hydroxytryptamine rec... 52 4e-06
BC028629-1|AAH28629.1| 492|Homo sapiens gamma-aminobutyric acid... 51 7e-06
AK122638-1|BAC85499.1| 266|Homo sapiens yte protein of 76kDa) (... 51 7e-06
U77731-2|AAB38273.1| 360|Homo sapiens glycine receptor alpha 2B... 50 9e-06
S62908-1|AAB27279.1| 492|Homo sapiens gamma-aminobutyric acidA ... 50 9e-06
CR450343-1|CAG29339.1| 452|Homo sapiens GLRA2 protein. 50 9e-06
AY437084-1|AAR87843.1| 452|Homo sapiens glycine receptor alpha2... 50 9e-06
AF166361-1|AAG12455.1| 492|Homo sapiens GABA receptor subunit a... 50 9e-06
X52008-1|CAA36257.1| 452|Homo sapiens inhibitory glycine recept... 50 1e-05
U77731-1|AAB38272.1| 360|Homo sapiens glycine receptor alpha 2 ... 50 1e-05
BC032864-1|AAH32864.1| 452|Homo sapiens glycine receptor, alpha... 50 1e-05
AY437083-1|AAR87842.1| 452|Homo sapiens glycine receptor alpha2... 50 1e-05
AF053495-1|AAC35290.1| 452|Homo sapiens glycine receptor alpha ... 50 1e-05
S82769-1|AAB39369.1| 467|Homo sapiens GABAA receptor gamma 3 su... 49 2e-05
AF269144-1|AAF99698.1| 467|Homo sapiens GABAA receptor gamma 3 ... 49 2e-05
AF228458-1|AAF63215.1| 449|Homo sapiens GABAA receptor gamma 3 ... 49 2e-05
U30461-1|AAB52519.1| 554|Homo sapiens GABAA receptor subunit al... 48 4e-05
BC035055-1|AAH35055.1| 554|Homo sapiens gamma-aminobutyric acid... 48 4e-05
S81944-1|AAB36480.1| 453|Homo sapiens gamma-aminobutyric acid t... 48 5e-05
BC099641-1|AAH99641.1| 453|Homo sapiens gamma-aminobutyric acid... 48 5e-05
BC099640-1|AAH99640.1| 453|Homo sapiens gamma-aminobutyric acid... 48 5e-05
BC096242-1|AAH96242.1| 453|Homo sapiens gamma-aminobutyric acid... 48 5e-05
BC096241-1|AAH96241.1| 453|Homo sapiens gamma-aminobutyric acid... 48 5e-05
BC022449-1|AAH22449.1| 474|Homo sapiens gamma-aminobutyric acid... 47 8e-05
BC096083-1|AAH96083.1| 198|Homo sapiens CHRNB4 protein protein. 47 1e-04
BC096081-1|AAH96081.1| 198|Homo sapiens CHRNB4 protein protein. 47 1e-04
BC033801-1|AAH33801.1| 452|Homo sapiens gamma-aminobutyric acid... 47 1e-04
AL391845-4|CAI15436.1| 452|Homo sapiens gamma-aminobutyric acid... 47 1e-04
AF016917-1|AAB70007.1| 452|Homo sapiens GABA-A receptor delta s... 47 1e-04
U93917-1|AAC39917.1| 449|Homo sapiens glycine receptor alpha 3 ... 46 1e-04
BC114947-1|AAI14948.1| 457|Homo sapiens GLRA1 protein protein. 46 1e-04
BC074980-1|AAH74980.1| 449|Homo sapiens glycine receptor, alpha... 46 1e-04
BC036086-1|AAH36086.1| 464|Homo sapiens glycine receptor, alpha... 46 1e-04
AF017724-1|AAC39919.1| 465|Homo sapiens glycine receptor alpha ... 46 1e-04
X52009-1|CAA36258.1| 449|Homo sapiens inhibitory glycine recept... 46 2e-04
U95367-1|AAC51357.1| 440|Homo sapiens GABA-A receptor pi subuni... 46 2e-04
BC109106-1|AAI09107.1| 440|Homo sapiens gamma-aminobutyric acid... 46 2e-04
BC109105-1|AAI09106.1| 440|Homo sapiens gamma-aminobutyric acid... 46 2e-04
BC074865-1|AAH74865.1| 440|Homo sapiens gamma-aminobutyric acid... 46 2e-04
BC074810-1|AAH74810.1| 440|Homo sapiens gamma-aminobutyric acid... 46 2e-04
AF009702-1|AAC24194.1| 440|Homo sapiens GABA-A receptor pi subu... 46 2e-04
BC109211-1|AAI09212.1| 632|Homo sapiens gamma-aminobutyric acid... 46 2e-04
BC109210-1|AAI09211.1| 632|Homo sapiens gamma-aminobutyric acid... 46 2e-04
BC074795-1|AAH74795.1| 467|Homo sapiens gamma-aminobutyric acid... 46 2e-04
BC069348-1|AAH69348.1| 467|Homo sapiens gamma-aminobutyric acid... 46 2e-04
BC059389-1|AAH59389.1| 475|Homo sapiens gamma-aminobutyric acid... 46 2e-04
AF189259-1|AAF70380.1| 632|Homo sapiens GABA-A receptor theta s... 46 2e-04
AF165124-1|AAD50273.1| 467|Homo sapiens gamma-aminobutyric acid... 46 2e-04
AF144648-1|AAD51172.1| 627|Homo sapiens GABA-A receptor theta p... 46 2e-04
X15376-1|CAA33437.1| 467|Homo sapiens GABA-A receptor gamma 2 s... 44 6e-04
Z93848-1|CAI41994.1| 376|Homo sapiens glycine receptor, alpha 4... 44 8e-04
AL049610-1|CAI42158.1| 376|Homo sapiens glycine receptor, alpha... 44 8e-04
BC114967-1|AAI14968.1| 366|Homo sapiens GLRA1 protein protein. 44 0.001
BC031087-1|AAH31087.1| 465|Homo sapiens gamma-aminobutyric acid... 44 0.001
AB209359-1|BAD92596.1| 533|Homo sapiens cholinergic receptor, n... 38 0.050
BC096291-1|AAH96291.1| 556|Homo sapiens CHRNA4 protein protein. 37 0.087
U83981-1|AAC25631.1| 674|Homo sapiens apoptosis associated prot... 31 5.7
CR457259-1|CAG33540.1| 674|Homo sapiens PPP1R15A protein. 31 5.7
BC003067-1|AAH03067.1| 674|Homo sapiens protein phosphatase 1, ... 31 5.7
AK001361-1|BAA91649.1| 674|Homo sapiens protein ( Homo sapiens ... 31 5.7
AK122582-1|BAC56923.1| 1383|Homo sapiens FLJ00269 protein protein. 30 10.0
>AJ306454-1|CAC34819.1| 497|Homo sapiens neuronal nicotinic
acetylcholine receptor beta-4 subunit protein.
Length = 497
Score = 74.1 bits (174), Expect = 6e-13
Identities = 50/179 (27%), Positives = 84/179 (46%), Gaps = 8/179 (4%)
Frame = +1
Query: 67 LLPFLLTCAIASAAECENATSLSLMIDSLL--ATYD---RDSPPDSKIV-VNLTLHLRHA 228
L+ F L A+ C A + ++D LL Y+ R + S+++ + L L L
Sbjct: 7 LVLFFLV-ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQL 65
Query: 229 -NIRESESTVRIQADLQMNWIDKRLSWNVGEW-GCSTWLVSSERLWRPDVVLLNAAATTA 402
++ E E + L+ W D RL+WN + G + + ++R+W PD+VL N T
Sbjct: 66 ISVNEREQIMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNDGTYE 125
Query: 403 GDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVI 579
V +NGSV W+ + +++ +P D Q CT KF S ++ E+D V+
Sbjct: 126 VSVYTNLIVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRSWTYDHTEIDMVL 184
>Y08416-1|CAA69693.1| 498|Homo sapiens nicotinic acetylcholine
receptor beta4 subunit precursor protein.
Length = 498
Score = 72.1 bits (169), Expect = 3e-12
Identities = 51/180 (28%), Positives = 85/180 (47%), Gaps = 9/180 (5%)
Frame = +1
Query: 67 LLPFLLTCAIASAAECENATSLSLMIDSLL--ATYD---RDSPPDSKIV-VNLTLHLRHA 228
L+ F L A+ C A + ++D LL Y+ R + S+++ + L L L
Sbjct: 7 LVLFFLV-ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQL 65
Query: 229 -NIRESESTVRIQADLQMNWIDKRLSWNVGEW-GCSTWLVSSERLWRPDVVLLNAA-ATT 399
++ E E + L+ W D RL+WN + G + + ++R+W PD+VL N A T
Sbjct: 66 ISVNEREQIMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNADGTY 125
Query: 400 AGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVI 579
V +NGSV W+ + +++ +P D Q CT KF S ++ E+D V+
Sbjct: 126 EVSVYTNLIVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRSWTYDHTEIDMVL 185
>U62439-1|AAB40117.1| 498|Homo sapiens nicotinic acetylcholine
receptor beta4 subunit precursor protein.
Length = 498
Score = 72.1 bits (169), Expect = 3e-12
Identities = 51/180 (28%), Positives = 85/180 (47%), Gaps = 9/180 (5%)
Frame = +1
Query: 67 LLPFLLTCAIASAAECENATSLSLMIDSLL--ATYD---RDSPPDSKIV-VNLTLHLRHA 228
L+ F L A+ C A + ++D LL Y+ R + S+++ + L L L
Sbjct: 7 LVLFFLV-ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQL 65
Query: 229 -NIRESESTVRIQADLQMNWIDKRLSWNVGEW-GCSTWLVSSERLWRPDVVLLNAA-ATT 399
++ E E + L+ W D RL+WN + G + + ++R+W PD+VL N A T
Sbjct: 66 ISVNEREQIMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNADGTY 125
Query: 400 AGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVI 579
V +NGSV W+ + +++ +P D Q CT KF S ++ E+D V+
Sbjct: 126 EVSVYTNLIVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRSWTYDHTEIDMVL 185
>U48861-1|AAA92123.1| 498|Homo sapiens beta 4 nicotinic
acetylcholine receptor subunit protein.
Length = 498
Score = 72.1 bits (169), Expect = 3e-12
Identities = 51/180 (28%), Positives = 85/180 (47%), Gaps = 9/180 (5%)
Frame = +1
Query: 67 LLPFLLTCAIASAAECENATSLSLMIDSLL--ATYD---RDSPPDSKIV-VNLTLHLRHA 228
L+ F L A+ C A + ++D LL Y+ R + S+++ + L L L
Sbjct: 7 LVLFFLV-ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQL 65
Query: 229 -NIRESESTVRIQADLQMNWIDKRLSWNVGEW-GCSTWLVSSERLWRPDVVLLNAA-ATT 399
++ E E + L+ W D RL+WN + G + + ++R+W PD+VL N A T
Sbjct: 66 ISVNEREQIMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNADGTY 125
Query: 400 AGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVI 579
V +NGSV W+ + +++ +P D Q CT KF S ++ E+D V+
Sbjct: 126 EVSVYTNLIVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRSWTYDHTEIDMVL 185
>BC096082-1|AAH96082.1| 498|Homo sapiens cholinergic receptor,
nicotinic, beta 4 protein.
Length = 498
Score = 72.1 bits (169), Expect = 3e-12
Identities = 51/180 (28%), Positives = 85/180 (47%), Gaps = 9/180 (5%)
Frame = +1
Query: 67 LLPFLLTCAIASAAECENATSLSLMIDSLL--ATYD---RDSPPDSKIV-VNLTLHLRHA 228
L+ F L A+ C A + ++D LL Y+ R + S+++ + L L L
Sbjct: 7 LVLFFLV-ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQL 65
Query: 229 -NIRESESTVRIQADLQMNWIDKRLSWNVGEW-GCSTWLVSSERLWRPDVVLLNAA-ATT 399
++ E E + L+ W D RL+WN + G + + ++R+W PD+VL N A T
Sbjct: 66 ISVNEREQIMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNADGTY 125
Query: 400 AGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVI 579
V +NGSV W+ + +++ +P D Q CT KF S ++ E+D V+
Sbjct: 126 EVSVYTNLIVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRSWTYDHTEIDMVL 185
>BC096080-1|AAH96080.1| 498|Homo sapiens cholinergic receptor,
nicotinic, beta 4 protein.
Length = 498
Score = 72.1 bits (169), Expect = 3e-12
Identities = 51/180 (28%), Positives = 85/180 (47%), Gaps = 9/180 (5%)
Frame = +1
Query: 67 LLPFLLTCAIASAAECENATSLSLMIDSLL--ATYD---RDSPPDSKIV-VNLTLHLRHA 228
L+ F L A+ C A + ++D LL Y+ R + S+++ + L L L
Sbjct: 7 LVLFFLV-ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQL 65
Query: 229 -NIRESESTVRIQADLQMNWIDKRLSWNVGEW-GCSTWLVSSERLWRPDVVLLNAA-ATT 399
++ E E + L+ W D RL+WN + G + + ++R+W PD+VL N A T
Sbjct: 66 ISVNEREQIMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNADGTY 125
Query: 400 AGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVI 579
V +NGSV W+ + +++ +P D Q CT KF S ++ E+D V+
Sbjct: 126 EVSVYTNLIVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRSWTYDHTEIDMVL 185
>AF306329-1|AAL02062.1| 498|Homo sapiens neuronal nicotinic
acetylcholine receptor beta 4 subunit protein.
Length = 498
Score = 72.1 bits (169), Expect = 3e-12
Identities = 51/180 (28%), Positives = 85/180 (47%), Gaps = 9/180 (5%)
Frame = +1
Query: 67 LLPFLLTCAIASAAECENATSLSLMIDSLL--ATYD---RDSPPDSKIV-VNLTLHLRHA 228
L+ F L A+ C A + ++D LL Y+ R + S+++ + L L L
Sbjct: 7 LVLFFLV-ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQL 65
Query: 229 -NIRESESTVRIQADLQMNWIDKRLSWNVGEW-GCSTWLVSSERLWRPDVVLLNAA-ATT 399
++ E E + L+ W D RL+WN + G + + ++R+W PD+VL N A T
Sbjct: 66 ISVNEREQIMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNADGTY 125
Query: 400 AGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVI 579
V +NGSV W+ + +++ +P D Q CT KF S ++ E+D V+
Sbjct: 126 EVSVYTNLIVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRSWTYDHTEIDMVL 185
>BT006897-1|AAP35543.1| 505|Homo sapiens cholinergic receptor,
nicotinic, alpha polypeptide 3 protein.
Length = 505
Score = 68.9 bits (161), Expect = 2e-11
Identities = 48/199 (24%), Positives = 91/199 (45%), Gaps = 8/199 (4%)
Frame = +1
Query: 46 MSTTYIILLPFLLTCAIASAAECENATSLSLMID--SLLATYDRDSPPDSKIVVNLTLHL 219
+S ++LL L +A A+E E+ L D ++ S P ++++ + +
Sbjct: 12 LSPPRLLLLLLLSLLPVARASEAEHRLFERLFEDYNEIIRPVANVSDP---VIIHFEVSM 68
Query: 220 RH-ANIRESESTVRIQADLQMNWIDKRLSWNVGEWGCSTWL-VSSERLWRPDVVLLN-AA 390
+ E + L+ W D +L WN ++G + ++ V ++++W+PD+VL N A
Sbjct: 69 SQLVKVDEVNQIMETNLWLKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAV 128
Query: 391 ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 570
D +A + G V+WI + + + +P D Q CT KFGS ++ ++D
Sbjct: 129 GDFQVDDKTKALLKYTGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKID 188
Query: 571 FVI---DQRIYXMFESRXW 618
V+ + +ES W
Sbjct: 189 LVLIGSSMNLKDYWESGEW 207
>BT006646-1|AAP35292.1| 489|Homo sapiens cholinergic receptor,
nicotinic, alpha polypeptide 3 protein.
Length = 489
Score = 68.9 bits (161), Expect = 2e-11
Identities = 48/199 (24%), Positives = 91/199 (45%), Gaps = 8/199 (4%)
Frame = +1
Query: 46 MSTTYIILLPFLLTCAIASAAECENATSLSLMID--SLLATYDRDSPPDSKIVVNLTLHL 219
+S ++LL L +A A+E E+ L D ++ S P ++++ + +
Sbjct: 12 LSPPRLLLLLLLSLLPVARASEAEHRLFERLFEDYNEIIRPVANVSDP---VIIHFEVSM 68
Query: 220 RH-ANIRESESTVRIQADLQMNWIDKRLSWNVGEWGCSTWL-VSSERLWRPDVVLLN-AA 390
+ E + L+ W D +L WN ++G + ++ V ++++W+PD+VL N A
Sbjct: 69 SQLVKVDEVNQIMETNLWLKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAV 128
Query: 391 ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 570
D +A + G V+WI + + + +P D Q CT KFGS ++ ++D
Sbjct: 129 GDFQVDDKTKALLKYTGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKID 188
Query: 571 FVI---DQRIYXMFESRXW 618
V+ + +ES W
Sbjct: 189 LVLIGSSMNLKDYWESGEW 207
>BC006114-1|AAH06114.1| 489|Homo sapiens CHRNA3 protein protein.
Length = 489
Score = 68.9 bits (161), Expect = 2e-11
Identities = 48/199 (24%), Positives = 91/199 (45%), Gaps = 8/199 (4%)
Frame = +1
Query: 46 MSTTYIILLPFLLTCAIASAAECENATSLSLMID--SLLATYDRDSPPDSKIVVNLTLHL 219
+S ++LL L +A A+E E+ L D ++ S P ++++ + +
Sbjct: 12 LSPPRLLLLLLLSLLPVARASEAEHRLFERLFEDYNEIIRPVANVSDP---VIIHFEVSM 68
Query: 220 RH-ANIRESESTVRIQADLQMNWIDKRLSWNVGEWGCSTWL-VSSERLWRPDVVLLN-AA 390
+ E + L+ W D +L WN ++G + ++ V ++++W+PD+VL N A
Sbjct: 69 SQLVKVDEVNQIMETNLWLKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAV 128
Query: 391 ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 570
D +A + G V+WI + + + +P D Q CT KFGS ++ ++D
Sbjct: 129 GDFQVDDKTKALLKYTGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKID 188
Query: 571 FVI---DQRIYXMFESRXW 618
V+ + +ES W
Sbjct: 189 LVLIGSSMNLKDYWESGEW 207
>BC002996-1|AAH02996.1| 505|Homo sapiens cholinergic receptor,
nicotinic, alpha 3 protein.
Length = 505
Score = 68.9 bits (161), Expect = 2e-11
Identities = 48/199 (24%), Positives = 91/199 (45%), Gaps = 8/199 (4%)
Frame = +1
Query: 46 MSTTYIILLPFLLTCAIASAAECENATSLSLMID--SLLATYDRDSPPDSKIVVNLTLHL 219
+S ++LL L +A A+E E+ L D ++ S P ++++ + +
Sbjct: 12 LSPPRLLLLLLLSLLPVARASEAEHRLFERLFEDYNEIIRPVANVSDP---VIIHFEVSM 68
Query: 220 RH-ANIRESESTVRIQADLQMNWIDKRLSWNVGEWGCSTWL-VSSERLWRPDVVLLN-AA 390
+ E + L+ W D +L WN ++G + ++ V ++++W+PD+VL N A
Sbjct: 69 SQLVKVDEVNQIMETNLWLKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAV 128
Query: 391 ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 570
D +A + G V+WI + + + +P D Q CT KFGS ++ ++D
Sbjct: 129 GDFQVDDKTKALLKYTGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKID 188
Query: 571 FVI---DQRIYXMFESRXW 618
V+ + +ES W
Sbjct: 189 LVLIGSSMNLKDYWESGEW 207
>BC001642-1|AAH01642.1| 505|Homo sapiens cholinergic receptor,
nicotinic, alpha 3 protein.
Length = 505
Score = 68.9 bits (161), Expect = 2e-11
Identities = 48/199 (24%), Positives = 91/199 (45%), Gaps = 8/199 (4%)
Frame = +1
Query: 46 MSTTYIILLPFLLTCAIASAAECENATSLSLMID--SLLATYDRDSPPDSKIVVNLTLHL 219
+S ++LL L +A A+E E+ L D ++ S P ++++ + +
Sbjct: 12 LSPPRLLLLLLLSLLPVARASEAEHRLFERLFEDYNEIIRPVANVSDP---VIIHFEVSM 68
Query: 220 RH-ANIRESESTVRIQADLQMNWIDKRLSWNVGEWGCSTWL-VSSERLWRPDVVLLN-AA 390
+ E + L+ W D +L WN ++G + ++ V ++++W+PD+VL N A
Sbjct: 69 SQLVKVDEVNQIMETNLWLKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAV 128
Query: 391 ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 570
D +A + G V+WI + + + +P D Q CT KFGS ++ ++D
Sbjct: 129 GDFQVDDKTKALLKYTGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKID 188
Query: 571 FVI---DQRIYXMFESRXW 618
V+ + +ES W
Sbjct: 189 LVLIGSSMNLKDYWESGEW 207
>BC000513-1|AAH00513.1| 505|Homo sapiens cholinergic receptor,
nicotinic, alpha 3 protein.
Length = 505
Score = 68.9 bits (161), Expect = 2e-11
Identities = 48/199 (24%), Positives = 91/199 (45%), Gaps = 8/199 (4%)
Frame = +1
Query: 46 MSTTYIILLPFLLTCAIASAAECENATSLSLMID--SLLATYDRDSPPDSKIVVNLTLHL 219
+S ++LL L +A A+E E+ L D ++ S P ++++ + +
Sbjct: 12 LSPPRLLLLLLLSLLPVARASEAEHRLFERLFEDYNEIIRPVANVSDP---VIIHFEVSM 68
Query: 220 RH-ANIRESESTVRIQADLQMNWIDKRLSWNVGEWGCSTWL-VSSERLWRPDVVLLN-AA 390
+ E + L+ W D +L WN ++G + ++ V ++++W+PD+VL N A
Sbjct: 69 SQLVKVDEVNQIMETNLWLKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAV 128
Query: 391 ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 570
D +A + G V+WI + + + +P D Q CT KFGS ++ ++D
Sbjct: 129 GDFQVDDKTKALLKYTGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKID 188
Query: 571 FVI---DQRIYXMFESRXW 618
V+ + +ES W
Sbjct: 189 LVLIGSSMNLKDYWESGEW 207
>AF385584-1|AAK68110.1| 489|Homo sapiens nicotinic cholinergic
receptor alpha 3 protein.
Length = 489
Score = 68.9 bits (161), Expect = 2e-11
Identities = 48/199 (24%), Positives = 91/199 (45%), Gaps = 8/199 (4%)
Frame = +1
Query: 46 MSTTYIILLPFLLTCAIASAAECENATSLSLMID--SLLATYDRDSPPDSKIVVNLTLHL 219
+S ++LL L +A A+E E+ L D ++ S P ++++ + +
Sbjct: 6 LSPPRLLLLLLLSLLPVARASEAEHRLFERLFEDYNEIIRPVANVSDP---VIIHFEVSM 62
Query: 220 RH-ANIRESESTVRIQADLQMNWIDKRLSWNVGEWGCSTWL-VSSERLWRPDVVLLN-AA 390
+ E + L+ W D +L WN ++G + ++ V ++++W+PD+VL N A
Sbjct: 63 SQLVKVDEVNQIMETNLWLKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAV 122
Query: 391 ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 570
D +A + G V+WI + + + +P D Q CT KFGS ++ ++D
Sbjct: 123 GDFQVDDKTKALLKYTGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKID 182
Query: 571 FVI---DQRIYXMFESRXW 618
V+ + +ES W
Sbjct: 183 LVLIGSSMNLKDYWESGEW 201
>Y08419-1|CAA69696.1| 468|Homo sapiens nicotinic acetylcholine
receptor alpha5 subunit precursor protein.
Length = 468
Score = 68.1 bits (159), Expect = 4e-11
Identities = 37/156 (23%), Positives = 75/156 (48%), Gaps = 6/156 (3%)
Frame = +1
Query: 139 MIDSLLATYDRDSPP----DSKIVVNLTLHLRH-ANIRESESTVRIQADLQMNWIDKRLS 303
++ L Y+R P + KI + L + ++ E + L+ WID +L
Sbjct: 50 LLKDLFQDYERWVRPVEHLNDKIKIKFGLAISQLVDVDEKNQLMTTNVWLKQEWIDVKLR 109
Query: 304 WNVGEWG-CSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVSWIKRLDISTP 480
WN ++G V S+ +W PD+VL + A + + + NG+V+W + +
Sbjct: 110 WNPDDYGGIKVIRVPSDSVWTPDIVLFDNADGRFEGTSTKTVIRYNGTVTWTPPANYKSS 169
Query: 481 ISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDQR 588
++ + +P D+Q C+ KFGS ++ ++D +++ +
Sbjct: 170 CTIDVTFFPFDLQNCSMKFGSWTYDGSQVDIILEDQ 205
>Y08418-1|CAA69695.1| 503|Homo sapiens nicotinic acetylcholine
receptor alpha3 subunit precursor protein.
Length = 503
Score = 68.1 bits (159), Expect = 4e-11
Identities = 48/192 (25%), Positives = 88/192 (45%), Gaps = 6/192 (3%)
Frame = +1
Query: 61 IILLPFLLTCAIASAAECENATSLSLMIDSLLATYDRDSPPDSKIVVNLTLHLRH-ANIR 237
++LL LL A AS AE L + ++ S P ++++ + + +
Sbjct: 17 LLLLLSLLPVARASEAEHRLFERLFEDYNEIIRPVANVSDP---VIIHFEVSMSQLVKVD 73
Query: 238 ESESTVRIQADLQMNWIDKRLSWNVGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDY 411
E + L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D
Sbjct: 74 EVNQIMETNLWLKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDD 133
Query: 412 ALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVI---D 582
+A + G V+WI + + + +P D Q CT KFGS ++ ++D V+
Sbjct: 134 KTKALLKYTGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVLIGSS 193
Query: 583 QRIYXMFESRXW 618
+ +ES W
Sbjct: 194 MNLKDYWESGEW 205
>U62434-1|AAB40112.1| 468|Homo sapiens nicotinic acetylcholine
receptor alpha5 subunit precursor protein.
Length = 468
Score = 68.1 bits (159), Expect = 4e-11
Identities = 37/156 (23%), Positives = 75/156 (48%), Gaps = 6/156 (3%)
Frame = +1
Query: 139 MIDSLLATYDRDSPP----DSKIVVNLTLHLRH-ANIRESESTVRIQADLQMNWIDKRLS 303
++ L Y+R P + KI + L + ++ E + L+ WID +L
Sbjct: 50 LLKDLFQDYERWVRPVEHLNDKIKIKFGLAISQLVDVDEKNQLMTTNVWLKQEWIDVKLR 109
Query: 304 WNVGEWG-CSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVSWIKRLDISTP 480
WN ++G V S+ +W PD+VL + A + + + NG+V+W + +
Sbjct: 110 WNPDDYGGIKVIRVPSDSVWTPDIVLFDNADGRFEGTSTKTVIRYNGTVTWTPPANYKSS 169
Query: 481 ISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDQR 588
++ + +P D+Q C+ KFGS ++ ++D +++ +
Sbjct: 170 CTIDVTFFPFDLQNCSMKFGSWTYDGSQVDIILEDQ 205
>U62432-1|AAB40110.1| 504|Homo sapiens nicotinic acetylcholine
receptor alpha3 subunit precursor protein.
Length = 504
Score = 68.1 bits (159), Expect = 4e-11
Identities = 48/192 (25%), Positives = 88/192 (45%), Gaps = 6/192 (3%)
Frame = +1
Query: 61 IILLPFLLTCAIASAAECENATSLSLMIDSLLATYDRDSPPDSKIVVNLTLHLRH-ANIR 237
++LL LL A AS AE L + ++ S P ++++ + + +
Sbjct: 18 LLLLLSLLPVARASEAEHRLFERLFEDYNEIIRPVANVSDP---VIIHFEVSMSQLVKVD 74
Query: 238 ESESTVRIQADLQMNWIDKRLSWNVGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDY 411
E + L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D
Sbjct: 75 EVNQIMETNLWLKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDD 134
Query: 412 ALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVI---D 582
+A + G V+WI + + + +P D Q CT KFGS ++ ++D V+
Sbjct: 135 KTKALLKYTGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVLIGSS 194
Query: 583 QRIYXMFESRXW 618
+ +ES W
Sbjct: 195 MNLKDYWESGEW 206
>M37981-1|AAA59942.1| 503|Homo sapiens neuronal nicotinic
acetylcholine receptor protein.
Length = 503
Score = 68.1 bits (159), Expect = 4e-11
Identities = 48/192 (25%), Positives = 88/192 (45%), Gaps = 6/192 (3%)
Frame = +1
Query: 61 IILLPFLLTCAIASAAECENATSLSLMIDSLLATYDRDSPPDSKIVVNLTLHLRH-ANIR 237
++LL LL A AS AE L + ++ S P ++++ + + +
Sbjct: 17 LLLLLSLLPVARASEAEHRLFERLFEDYNEIIRPVANVSDP---VIIHFEVSMSQLVKVD 73
Query: 238 ESESTVRIQADLQMNWIDKRLSWNVGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDY 411
E + L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D
Sbjct: 74 EVNQIMETNLWLKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDD 133
Query: 412 ALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVI---D 582
+A + G V+WI + + + +P D Q CT KFGS ++ ++D V+
Sbjct: 134 KTKALLKYTGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVLIGSS 193
Query: 583 QRIYXMFESRXW 618
+ +ES W
Sbjct: 194 MNLKDYWESGEW 205
>BC098443-1|AAH98443.1| 504|Homo sapiens cholinergic receptor,
nicotinic, alpha 3 protein.
Length = 504
Score = 68.1 bits (159), Expect = 4e-11
Identities = 48/192 (25%), Positives = 88/192 (45%), Gaps = 6/192 (3%)
Frame = +1
Query: 61 IILLPFLLTCAIASAAECENATSLSLMIDSLLATYDRDSPPDSKIVVNLTLHLRH-ANIR 237
++LL LL A AS AE L + ++ S P ++++ + + +
Sbjct: 18 LLLLLSLLPVARASEAEHRLFERLFEDYNEIIRPVANVSDP---VIIHFEVSMSQLVKVD 74
Query: 238 ESESTVRIQADLQMNWIDKRLSWNVGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDY 411
E + L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D
Sbjct: 75 EVNQIMETNLWLKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDD 134
Query: 412 ALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVI---D 582
+A + G V+WI + + + +P D Q CT KFGS ++ ++D V+
Sbjct: 135 KTKALLKYTGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVLIGSS 194
Query: 583 QRIYXMFESRXW 618
+ +ES W
Sbjct: 195 MNLKDYWESGEW 206
>BC033639-1|AAH33639.1| 468|Homo sapiens cholinergic receptor,
nicotinic, alpha 5 protein.
Length = 468
Score = 68.1 bits (159), Expect = 4e-11
Identities = 37/156 (23%), Positives = 75/156 (48%), Gaps = 6/156 (3%)
Frame = +1
Query: 139 MIDSLLATYDRDSPP----DSKIVVNLTLHLRH-ANIRESESTVRIQADLQMNWIDKRLS 303
++ L Y+R P + KI + L + ++ E + L+ WID +L
Sbjct: 50 LLKDLFQDYERWVRPVEHLNDKIKIKFGLAISQLVDVDEKNQLMTTNVWLKQEWIDVKLR 109
Query: 304 WNVGEWG-CSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVSWIKRLDISTP 480
WN ++G V S+ +W PD+VL + A + + + NG+V+W + +
Sbjct: 110 WNPDDYGGIKVIRVPSDSVWTPDIVLFDNADGRFEGTSTKTVIRYNGTVTWTPPANYKSS 169
Query: 481 ISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDQR 588
++ + +P D+Q C+ KFGS ++ ++D +++ +
Sbjct: 170 CTIDVTFFPFDLQNCSMKFGSWTYDGSQVDIILEDQ 205
>AJ306481-1|CAC34820.1| 468|Homo sapiens neuronal nicotinic
acetylcholine receptor alpha-5subunit protein.
Length = 468
Score = 68.1 bits (159), Expect = 4e-11
Identities = 37/156 (23%), Positives = 75/156 (48%), Gaps = 6/156 (3%)
Frame = +1
Query: 139 MIDSLLATYDRDSPP----DSKIVVNLTLHLRH-ANIRESESTVRIQADLQMNWIDKRLS 303
++ L Y+R P + KI + L + ++ E + L+ WID +L
Sbjct: 50 LLKDLFQDYERWVRPVEHLNDKIKIKFGLAISQLVDVDEKNQLMTTNVWLKQEWIDVKLR 109
Query: 304 WNVGEWG-CSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVSWIKRLDISTP 480
WN ++G V S+ +W PD+VL + A + + + NG+V+W + +
Sbjct: 110 WNPDDYGGIKVIRVPSDSVWTPDIVLFDNADGRFEGTSTKTVIRYNGTVTWTPPANYKSS 169
Query: 481 ISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDQR 588
++ + +P D+Q C+ KFGS ++ ++D +++ +
Sbjct: 170 CTIDVTFFPFDLQNCSMKFGSWTYDGSQVDIILEDQ 205
>AJ007783-1|CAA07682.1| 504|Homo sapiens nicotinic acetylcholine
receptor alpha-3 subunit protein.
Length = 504
Score = 68.1 bits (159), Expect = 4e-11
Identities = 48/192 (25%), Positives = 88/192 (45%), Gaps = 6/192 (3%)
Frame = +1
Query: 61 IILLPFLLTCAIASAAECENATSLSLMIDSLLATYDRDSPPDSKIVVNLTLHLRH-ANIR 237
++LL LL A AS AE L + ++ S P ++++ + + +
Sbjct: 18 LLLLLSLLPVARASEAEHRLFERLFEDYNEIIRPVANVSDP---VIIHFEVSMSQLVKVD 74
Query: 238 ESESTVRIQADLQMNWIDKRLSWNVGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDY 411
E + L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D
Sbjct: 75 EVNQIMETNLWLKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDD 134
Query: 412 ALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVI---D 582
+A + G V+WI + + + +P D Q CT KFGS ++ ++D V+
Sbjct: 135 KTKALLKYTGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVLIGSS 194
Query: 583 QRIYXMFESRXW 618
+ +ES W
Sbjct: 195 MNLKDYWESGEW 206
>X68275-1|CAA48336.1| 451|Homo sapiens nicotinic receptor beta 4
subunit protein.
Length = 451
Score = 67.7 bits (158), Expect = 5e-11
Identities = 39/132 (29%), Positives = 64/132 (48%), Gaps = 3/132 (2%)
Frame = +1
Query: 193 IVVNLTLHLRHA-NIRESESTVRIQADLQMNWIDKRLSWNVGEW-GCSTWLVSSERLWRP 366
I + L L L ++ E + + L+ W D RL+WN + G + + ++R+W P
Sbjct: 7 ISIKLQLSLAQLISVNERDEIMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLP 66
Query: 367 DVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 543
D+VL N A T V +NGSV W+ + +++ +P D Q CT KF S
Sbjct: 67 DIVLYNNADGTYEVSVYTNLIVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRS 126
Query: 544 RMHNSDEMDFVI 579
++ E+D V+
Sbjct: 127 WTYDHTEIDMVL 138
>Y08417-1|CAA69694.1| 458|Homo sapiens nicotinic acetylcholine
receptor beta3 subunit precursor protein.
Length = 458
Score = 67.3 bits (157), Expect = 7e-11
Identities = 35/119 (29%), Positives = 57/119 (47%), Gaps = 2/119 (1%)
Frame = +1
Query: 229 NIRESESTVRIQADLQMNWIDKRLSWNVGEWG-CSTWLVSSERLWRPDVVLL-NAAATTA 402
++ E + L+ W D +L WN ++G + V SE LW PD+VL NA
Sbjct: 67 DVDEKNQLMTTNVWLKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFE 126
Query: 403 GDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVI 579
G + V +NG+V W + +M + +P D Q C+ KFGS ++ +D ++
Sbjct: 127 GSLMTKVIVKSNGTVVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGTMVDLIL 185
>X67513-1|CAA47851.1| 423|Homo sapiens nicotinic acetylcholine
receptor beta-3 subunit protein.
Length = 423
Score = 67.3 bits (157), Expect = 7e-11
Identities = 35/119 (29%), Positives = 57/119 (47%), Gaps = 2/119 (1%)
Frame = +1
Query: 229 NIRESESTVRIQADLQMNWIDKRLSWNVGEWG-CSTWLVSSERLWRPDVVLL-NAAATTA 402
++ E + L+ W D +L WN ++G + V SE LW PD+VL NA
Sbjct: 32 DVDEKNQLMTTNVWLKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFE 91
Query: 403 GDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVI 579
G + V +NG+V W + +M + +P D Q C+ KFGS ++ +D ++
Sbjct: 92 GSLMTKVIVKSNGTVVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGTMVDLIL 150
>U62438-1|AAB40116.1| 458|Homo sapiens nicotinic acetylcholine
receptor beta3 subunit precursor protein.
Length = 458
Score = 67.3 bits (157), Expect = 7e-11
Identities = 35/119 (29%), Positives = 57/119 (47%), Gaps = 2/119 (1%)
Frame = +1
Query: 229 NIRESESTVRIQADLQMNWIDKRLSWNVGEWG-CSTWLVSSERLWRPDVVLL-NAAATTA 402
++ E + L+ W D +L WN ++G + V SE LW PD+VL NA
Sbjct: 67 DVDEKNQLMTTNVWLKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFE 126
Query: 403 GDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVI 579
G + V +NG+V W + +M + +P D Q C+ KFGS ++ +D ++
Sbjct: 127 GSLMTKVIVKSNGTVVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGTMVDLIL 185
>BC069788-1|AAH69788.1| 458|Homo sapiens cholinergic receptor,
nicotinic, beta 3 protein.
Length = 458
Score = 67.3 bits (157), Expect = 7e-11
Identities = 35/119 (29%), Positives = 57/119 (47%), Gaps = 2/119 (1%)
Frame = +1
Query: 229 NIRESESTVRIQADLQMNWIDKRLSWNVGEWG-CSTWLVSSERLWRPDVVLL-NAAATTA 402
++ E + L+ W D +L WN ++G + V SE LW PD+VL NA
Sbjct: 67 DVDEKNQLMTTNVWLKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFE 126
Query: 403 GDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVI 579
G + V +NG+V W + +M + +P D Q C+ KFGS ++ +D ++
Sbjct: 127 GSLMTKVIVKSNGTVVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGTMVDLIL 185
>BC069703-1|AAH69703.1| 458|Homo sapiens cholinergic receptor,
nicotinic, beta 3 protein.
Length = 458
Score = 67.3 bits (157), Expect = 7e-11
Identities = 35/119 (29%), Positives = 57/119 (47%), Gaps = 2/119 (1%)
Frame = +1
Query: 229 NIRESESTVRIQADLQMNWIDKRLSWNVGEWG-CSTWLVSSERLWRPDVVLL-NAAATTA 402
++ E + L+ W D +L WN ++G + V SE LW PD+VL NA
Sbjct: 67 DVDEKNQLMTTNVWLKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFE 126
Query: 403 GDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVI 579
G + V +NG+V W + +M + +P D Q C+ KFGS ++ +D ++
Sbjct: 127 GSLMTKVIVKSNGTVVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGTMVDLIL 185
>BC069681-1|AAH69681.1| 458|Homo sapiens cholinergic receptor,
nicotinic, beta 3 protein.
Length = 458
Score = 67.3 bits (157), Expect = 7e-11
Identities = 35/119 (29%), Positives = 57/119 (47%), Gaps = 2/119 (1%)
Frame = +1
Query: 229 NIRESESTVRIQADLQMNWIDKRLSWNVGEWG-CSTWLVSSERLWRPDVVLL-NAAATTA 402
++ E + L+ W D +L WN ++G + V SE LW PD+VL NA
Sbjct: 67 DVDEKNQLMTTNVWLKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFE 126
Query: 403 GDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVI 579
G + V +NG+V W + +M + +P D Q C+ KFGS ++ +D ++
Sbjct: 127 GSLMTKVIVKSNGTVVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGTMVDLIL 185
>AF140765-1|AAD33063.1| 458|Homo sapiens neuronal acetylcholine
receptor beta-3 subunit precursor protein.
Length = 458
Score = 67.3 bits (157), Expect = 7e-11
Identities = 35/119 (29%), Positives = 57/119 (47%), Gaps = 2/119 (1%)
Frame = +1
Query: 229 NIRESESTVRIQADLQMNWIDKRLSWNVGEWG-CSTWLVSSERLWRPDVVLL-NAAATTA 402
++ E + L+ W D +L WN ++G + V SE LW PD+VL NA
Sbjct: 67 DVDEKNQLMTTNVWLKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFE 126
Query: 403 GDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVI 579
G + V +NG+V W + +M + +P D Q C+ KFGS ++ +D ++
Sbjct: 127 GSLMTKVIVKSNGTVVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGTMVDLIL 185
>M83712-1|AAA58357.1| 468|Homo sapiens nicotinic receptor alpha 5
subunit protein.
Length = 468
Score = 66.9 bits (156), Expect = 9e-11
Identities = 37/156 (23%), Positives = 74/156 (47%), Gaps = 6/156 (3%)
Frame = +1
Query: 139 MIDSLLATYDRDSPP----DSKIVVNLTLHLRH-ANIRESESTVRIQADLQMNWIDKRLS 303
++ L Y+R P + KI + L + ++ E + L+ WID +L
Sbjct: 50 LLKDLFQDYERWVRPVEHLNDKIKIKFGLAISQLVDVDEKNQLMTTNVWLKQEWIDVKLR 109
Query: 304 WNVGEWG-CSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVSWIKRLDISTP 480
WN ++G V S+ W PD+VL + A + + + NG+V+W + +
Sbjct: 110 WNPDDYGGIKVIRVPSDSSWTPDIVLFDNADGRFEGTSTKTVIRYNGTVTWTPPANYKSS 169
Query: 481 ISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDQR 588
++ + +P D+Q C+ KFGS ++ ++D +++ +
Sbjct: 170 CTIDVTFFPFDLQNCSMKFGSWTYDGSQVDIILEDQ 205
>Y16282-1|CAA76155.1| 494|Homo sapiens nicotinic acetylcholine
receptor alpha6 subunit precursor protein.
Length = 494
Score = 66.5 bits (155), Expect = 1e-10
Identities = 43/166 (25%), Positives = 78/166 (46%), Gaps = 10/166 (6%)
Frame = +1
Query: 112 CENATSLSLMIDSLLATYDRDSPPDSKIVVNLTLHL-----RHANIRESESTVRIQADLQ 276
C + + L + Y++ P + +T+H + AN+ E + L+
Sbjct: 28 CVGCATEERLFHKLFSHYNQFIRPVENVSDPVTVHFEVAITQLANVDEVNQIMETNLWLR 87
Query: 277 MNWIDKRLSWNVGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNG 441
W D +L W+ E+ G T V ++++W+PD+VL N A GD+ + +A + NG
Sbjct: 88 HIWNDYKLRWDPMEYDGIETLRVPADKIWKPDIVLYNNAV---GDFQVEGKTKALLKYNG 144
Query: 442 SVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVI 579
++W + M + +P D Q C+ KFGS ++ E+D +I
Sbjct: 145 MITWTPPAIFKSSCPMDITFFPFDHQNCSLKFGSWTYDKAEIDLLI 190
>X53559-1|CAA37625.1| 474|Homo sapiens neuronal nicotinic
acetylcholine receptor alpha-3merase protein.
Length = 474
Score = 66.5 bits (155), Expect = 1e-10
Identities = 35/121 (28%), Positives = 62/121 (51%), Gaps = 5/121 (4%)
Frame = +1
Query: 271 LQMNWIDKRLSWNVGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 444
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 56 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 115
Query: 445 VSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVI---DQRIYXMFESRX 615
V+WI + + + +P D Q CT KFGS ++ ++D V+ + +ES
Sbjct: 116 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVLIGSSMNLKDYWESGE 175
Query: 616 W 618
W
Sbjct: 176 W 176
>U62435-1|AAB40113.1| 494|Homo sapiens nicotinic acetylcholine
receptor alpha6 subunit precursor protein.
Length = 494
Score = 66.5 bits (155), Expect = 1e-10
Identities = 43/166 (25%), Positives = 78/166 (46%), Gaps = 10/166 (6%)
Frame = +1
Query: 112 CENATSLSLMIDSLLATYDRDSPPDSKIVVNLTLHL-----RHANIRESESTVRIQADLQ 276
C + + L + Y++ P + +T+H + AN+ E + L+
Sbjct: 28 CVGCATEERLFHKLFSHYNQFIRPVENVSDPVTVHFEVAITQLANVDEVNQIMETNLWLR 87
Query: 277 MNWIDKRLSWNVGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNG 441
W D +L W+ E+ G T V ++++W+PD+VL N A GD+ + +A + NG
Sbjct: 88 HIWNDYKLRWDPMEYDGIETLRVPADKIWKPDIVLYNNAV---GDFQVEGKTKALLKYNG 144
Query: 442 SVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVI 579
++W + M + +P D Q C+ KFGS ++ E+D +I
Sbjct: 145 MITWTPPAIFKSSCPMDITFFPFDHQNCSLKFGSWTYDKAEIDLLI 190
>BC014456-1|AAH14456.1| 494|Homo sapiens cholinergic receptor,
nicotinic, alpha 6 protein.
Length = 494
Score = 66.5 bits (155), Expect = 1e-10
Identities = 43/166 (25%), Positives = 78/166 (46%), Gaps = 10/166 (6%)
Frame = +1
Query: 112 CENATSLSLMIDSLLATYDRDSPPDSKIVVNLTLHL-----RHANIRESESTVRIQADLQ 276
C + + L + Y++ P + +T+H + AN+ E + L+
Sbjct: 28 CVGCATEERLFHKLFSHYNQFIRPVENVSDPVTVHFEVAITQLANVDEVNQIMETNLWLR 87
Query: 277 MNWIDKRLSWNVGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNG 441
W D +L W+ E+ G T V ++++W+PD+VL N A GD+ + +A + NG
Sbjct: 88 HIWNDYKLRWDPMEYDGIETLRVPADKIWKPDIVLYNNAV---GDFQVEGKTKALLKYNG 144
Query: 442 SVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVI 579
++W + M + +P D Q C+ KFGS ++ E+D +I
Sbjct: 145 MITWTPPAIFKSSCPMDITFFPFDHQNCSLKFGSWTYDKAEIDLLI 190
>AB079251-1|BAC06855.1| 494|Homo sapiens Nicotinic acetylcholine
receptor alpha 6 protein.
Length = 494
Score = 66.5 bits (155), Expect = 1e-10
Identities = 43/166 (25%), Positives = 78/166 (46%), Gaps = 10/166 (6%)
Frame = +1
Query: 112 CENATSLSLMIDSLLATYDRDSPPDSKIVVNLTLHL-----RHANIRESESTVRIQADLQ 276
C + + L + Y++ P + +T+H + AN+ E + L+
Sbjct: 28 CVGCATEERLFHKLFSHYNQFIRPVENVSDPVTVHFEVAITQLANVDEVNQIMETNLWLR 87
Query: 277 MNWIDKRLSWNVGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNG 441
W D +L W+ E+ G T V ++++W+PD+VL N A GD+ + +A + NG
Sbjct: 88 HIWNDYKLRWDPMEYDGIETLRVPADKIWKPDIVLYNNAV---GDFQVEGKTKALLKYNG 144
Query: 442 SVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVI 579
++W + M + +P D Q C+ KFGS ++ E+D +I
Sbjct: 145 MITWTPPAIFKSSCPMDITFFPFDHQNCSLKFGSWTYDKAEIDLLI 190
>M86383-1|AAC84176.1| 502|Homo sapiens nicotinic acetylcholine
receptor alpha 3 subunit precursor protein.
Length = 502
Score = 65.7 bits (153), Expect = 2e-10
Identities = 49/195 (25%), Positives = 90/195 (46%), Gaps = 9/195 (4%)
Frame = +1
Query: 61 IILLPFLLTCAIASAAECENATSLSLMIDSLLATYDRDSPPDSKIVVNLTLHLRH-ANIR 237
++LL LL A AS AE L + ++ S P ++++ + + +
Sbjct: 16 LLLLLSLLPVARASEAEHRLFERLFEDYNEIIRPVANVSDP---VIIHFEVSMSQLVKVD 72
Query: 238 ESESTVRIQADLQMNWIDKRLSWNVGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYA 414
E + L+ W D +L WN +G + ++ V ++++W+PD+VL N A GD+
Sbjct: 73 EVNQIMETNLWLKQIWNDYKLKWNPSGYGGAEFMRVPAQKIWKPDIVLYNNAV---GDFQ 129
Query: 415 L----RARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVI- 579
+ +A + G V+WI + + + +P D Q CT KFGS ++ ++D V+
Sbjct: 130 VTTKTKALLKYTGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVLI 189
Query: 580 --DQRIYXMFESRXW 618
+ +ES W
Sbjct: 190 GSSMNLKDYWESGEW 204
>X01715-1|CAA25861.1| 520|Homo sapiens acetylcholine receptor gamma
chain precursor protein.
Length = 520
Score = 65.3 bits (152), Expect = 3e-10
Identities = 51/183 (27%), Positives = 85/183 (46%), Gaps = 8/183 (4%)
Frame = +1
Query: 61 IILLPFLLTCAIASAAECENATSLSLMIDSLLATYDRDSPPDSKI--VVNLTLHLRHANI 234
++LL L C + N L+ D L+ YD + P + VVN++L L N+
Sbjct: 8 LLLLLLLAVCLGGTQRNLRNQEE-RLLAD-LMQNYDPNLRPAERDSDVVNVSLKLTLTNL 65
Query: 235 ---RESESTVRIQADLQMNWIDKRLSWNVGEW-GCSTWLVSSERLWRPDVVLLNAAATTA 402
E E + ++M W D RL W+ ++ G V S +WRPD+VL N
Sbjct: 66 ISLNEREEALTTNVWIEMQWCDYRLRWDPRDYEGLWVLRVPSTMVWRPDIVLENNVDGVF 125
Query: 403 GDYALRARV--SNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFV 576
+ AL V S +G + W+ + S+ + +P D Q C+ F S+ ++++E+D
Sbjct: 126 -EVALYCNVLVSPDGCIYWLPPAIFRSACSISVTYFPFDWQNCSLIFQSQTYSTNEIDLQ 184
Query: 577 IDQ 585
+ Q
Sbjct: 185 LSQ 187
>AC092165-3|AAY24103.1| 520|Homo sapiens unknown protein.
Length = 520
Score = 65.3 bits (152), Expect = 3e-10
Identities = 51/183 (27%), Positives = 85/183 (46%), Gaps = 8/183 (4%)
Frame = +1
Query: 61 IILLPFLLTCAIASAAECENATSLSLMIDSLLATYDRDSPPDSKI--VVNLTLHLRHANI 234
++LL L C + N L+ D L+ YD + P + VVN++L L N+
Sbjct: 8 LLLLLLLAVCLGGTQRNLRNQEE-RLLAD-LMQNYDPNLRPAERDSDVVNVSLKLTLTNL 65
Query: 235 ---RESESTVRIQADLQMNWIDKRLSWNVGEW-GCSTWLVSSERLWRPDVVLLNAAATTA 402
E E + ++M W D RL W+ ++ G V S +WRPD+VL N
Sbjct: 66 ISLNEREEALTTNVWIEMQWCDYRLRWDPRDYEGLWVLRVPSTMVWRPDIVLENNVDGVF 125
Query: 403 GDYALRARV--SNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFV 576
+ AL V S +G + W+ + S+ + +P D Q C+ F S+ ++++E+D
Sbjct: 126 -EVALYCNVLVSPDGCIYWLPPAIFRSACSISVTYFPFDWQNCSLIFQSQTYSTNEIDLQ 184
Query: 577 IDQ 585
+ Q
Sbjct: 185 LSQ 187
>Y16281-1|CAA76154.1| 529|Homo sapiens nicotinic acetylcholine
receptor alpha2 subunit precursor protein.
Length = 529
Score = 64.5 bits (150), Expect = 5e-10
Identities = 40/137 (29%), Positives = 67/137 (48%), Gaps = 7/137 (5%)
Frame = +1
Query: 229 NIRESESTVRIQADLQMNWIDKRLSWNVGEWGCSTWL-VSSERLWRPDVVLLNAA-ATTA 402
++ E + L+ W D +L WN ++G T L V SE +W PD+VL N A A
Sbjct: 97 DVDEKNQMMTTNVWLKQEWSDYKLRWNPADFGNITSLRVPSEMIWIPDIVLYNNADGEFA 156
Query: 403 GDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNS-----DEM 567
+ +A + + G+V W+ + S+ + +P D Q C KFGS ++ ++M
Sbjct: 157 VTHMTKAHLFSTGTVHWVPPAIYKSSCSIDVTFFPFDQQNCKMKFGSWTYDKAKIDLEQM 216
Query: 568 DFVIDQRIYXMFESRXW 618
+ +D + Y +ES W
Sbjct: 217 EQTVDLKDY--WESGEW 231
>U62431-1|AAB40109.1| 529|Homo sapiens nicotinic acetylcholine
receptor alpha2 subunit precursor protein.
Length = 529
Score = 64.5 bits (150), Expect = 5e-10
Identities = 40/137 (29%), Positives = 67/137 (48%), Gaps = 7/137 (5%)
Frame = +1
Query: 229 NIRESESTVRIQADLQMNWIDKRLSWNVGEWGCSTWL-VSSERLWRPDVVLLNAA-ATTA 402
++ E + L+ W D +L WN ++G T L V SE +W PD+VL N A A
Sbjct: 97 DVDEKNQMMTTNVWLKQEWSDYKLRWNPADFGNITSLRVPSEMIWIPDIVLYNNADGEFA 156
Query: 403 GDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNS-----DEM 567
+ +A + + G+V W+ + S+ + +P D Q C KFGS ++ ++M
Sbjct: 157 VTHMTKAHLFSTGTVHWVPPAIYKSSCSIDVTFFPFDQQNCKMKFGSWTYDKAKIDLEQM 216
Query: 568 DFVIDQRIYXMFESRXW 618
+ +D + Y +ES W
Sbjct: 217 EQTVDLKDY--WESGEW 231
>X14830-1|CAA32939.1| 501|Homo sapiens protein ( Human mRNA for
muscle acetylcholine receptor beta-subunit. ).
Length = 501
Score = 64.1 bits (149), Expect = 7e-10
Identities = 45/130 (34%), Positives = 68/130 (52%), Gaps = 4/130 (3%)
Frame = +1
Query: 190 KIVVNLTL-HLRHANIRESESTVRIQADLQMNWIDKRLSWNVGEW-GCSTWLVSSERLWR 363
++ V L L L N ++ E + ++ DL+ W D RLSW+ E G + +++E +W
Sbjct: 53 RVSVGLILAQLISLNEKDEEMSTKVYLDLE--WTDYRLSWDPAEHDGIDSLRITAESVWL 110
Query: 364 PDVVLLNAAATTAGDYAL--RARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKF 537
PDVVLLN D AL VS++GSV W + S+Q+ +P D Q CT F
Sbjct: 111 PDVVLLNNNDGNF-DVALDISVVVSSDGSVRWQPPGIYRSSCSIQVTYFPFDWQNCTMVF 169
Query: 538 GSRMHNSDEM 567
S ++S E+
Sbjct: 170 SSYSYDSSEV 179
>BC011371-1|AAH11371.1| 501|Homo sapiens cholinergic receptor,
nicotinic, beta 1 (muscle) protein.
Length = 501
Score = 64.1 bits (149), Expect = 7e-10
Identities = 45/130 (34%), Positives = 68/130 (52%), Gaps = 4/130 (3%)
Frame = +1
Query: 190 KIVVNLTL-HLRHANIRESESTVRIQADLQMNWIDKRLSWNVGEW-GCSTWLVSSERLWR 363
++ V L L L N ++ E + ++ DL+ W D RLSW+ E G + +++E +W
Sbjct: 53 RVSVGLILAQLISLNEKDEEMSTKVYLDLE--WTDYRLSWDPAEHDGIDSLRITAESVWL 110
Query: 364 PDVVLLNAAATTAGDYAL--RARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKF 537
PDVVLLN D AL VS++GSV W + S+Q+ +P D Q CT F
Sbjct: 111 PDVVLLNNNDGNF-DVALDISVVVSSDGSVRWQPPGIYRSSCSIQVTYFPFDWQNCTMVF 169
Query: 538 GSRMHNSDEM 567
S ++S E+
Sbjct: 170 SSYSYDSSEV 179
>X66403-1|CAA47030.1| 493|Homo sapiens acetylcholine receptor
epsilon subunit CHRNE protein.
Length = 493
Score = 63.7 bits (148), Expect = 9e-10
Identities = 36/134 (26%), Positives = 71/134 (52%), Gaps = 3/134 (2%)
Frame = +1
Query: 181 PDSKIVVNLTLHLRHA-NIRESESTVRIQADLQMNWIDKRLSWNVGEWG-CSTWLVSSER 354
P+ + ++L + L + ++ E E T+ + ++W D RL+++ ++G T V SE
Sbjct: 45 PEDTVTISLKVTLTNLISLNEKEETLTTSVWIGIDWQDYRLNYSKDDFGGIETLRVPSEL 104
Query: 355 LWRPDVVLLNAAATTAG-DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTF 531
+W P++VL N G Y V GSV+W+ + ++++ +P D Q C+
Sbjct: 105 VWLPEIVLENNIDGQFGVAYDANVLVYEGGSVTWLPPAIYRSVCAVEVTYFPFDWQNCSL 164
Query: 532 KFGSRMHNSDEMDF 573
F S+ +N++E++F
Sbjct: 165 IFRSQTYNAEEVEF 178
>AF105999-1|AAD24503.1| 493|Homo sapiens acetylcholine receptor
epsilon subunit protein.
Length = 493
Score = 63.7 bits (148), Expect = 9e-10
Identities = 36/134 (26%), Positives = 71/134 (52%), Gaps = 3/134 (2%)
Frame = +1
Query: 181 PDSKIVVNLTLHLRHA-NIRESESTVRIQADLQMNWIDKRLSWNVGEWG-CSTWLVSSER 354
P+ + ++L + L + ++ E E T+ + ++W D RL+++ ++G T V SE
Sbjct: 45 PEDTVTISLKVTLTNLISLNEKEETLTTSVWIGIDWQDYRLNYSKDDFGGIETLRVPSEL 104
Query: 355 LWRPDVVLLNAAATTAG-DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTF 531
+W P++VL N G Y V GSV+W+ + ++++ +P D Q C+
Sbjct: 105 VWLPEIVLENNIDGQFGVAYDANVLVYEGGSVTWLPPAIYRSVCAVEVTYFPFDWQNCSL 164
Query: 532 KFGSRMHNSDEMDF 573
F S+ +N++E++F
Sbjct: 165 IFRSQTYNAEEVEF 178
>Y08421-1|CAA69698.1| 627|Homo sapiens nicotinic acetylcholine
receptor alpha4 subunit precursor protein.
Length = 627
Score = 62.9 bits (146), Expect = 2e-09
Identities = 50/181 (27%), Positives = 89/181 (49%), Gaps = 11/181 (6%)
Frame = +1
Query: 67 LLPFLLTCAIASAAECEN-ATSLSLMIDSLLATYDRDSPPDSKI--VVNLTLHLRHA--- 228
LL L T + +++ E A + ++ L + Y++ S P + I VV + L A
Sbjct: 15 LLLLLGTGLLRASSHVETRAHAEERLLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLI 74
Query: 229 NIRESESTVRIQADLQMNWIDKRLSWNVGEWGCSTWL-VSSERLWRPDVVLLNAAATTAG 405
++ E + ++ W D +L W+ ++ T + + SE +WRPD+VL N A G
Sbjct: 75 DVDEKNQMMTTNVWVKQEWHDYKLRWDPADYENVTSIRIPSELIWRPDIVLYNNAD---G 131
Query: 406 DYAL----RARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDF 573
D+A+ +A + ++G V W + S+ + +P D Q CT KFGS ++ ++D
Sbjct: 132 DFAVTHLTKAHLFHDGRVQWTPPAIYKSSCSIDVTFFPFDQQNCTMKFGSWTYDKAKIDL 191
Query: 574 V 576
V
Sbjct: 192 V 192
>X89741-1|CAA61893.1| 627|Homo sapiens neuronal acetylcholine
receptor alpha-4 subunit protein.
Length = 627
Score = 62.9 bits (146), Expect = 2e-09
Identities = 50/181 (27%), Positives = 89/181 (49%), Gaps = 11/181 (6%)
Frame = +1
Query: 67 LLPFLLTCAIASAAECEN-ATSLSLMIDSLLATYDRDSPPDSKI--VVNLTLHLRHA--- 228
LL L T + +++ E A + ++ L + Y++ S P + I VV + L A
Sbjct: 15 LLLLLGTGLLRASSHVETRAHAEERLLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLI 74
Query: 229 NIRESESTVRIQADLQMNWIDKRLSWNVGEWGCSTWL-VSSERLWRPDVVLLNAAATTAG 405
++ E + ++ W D +L W+ ++ T + + SE +WRPD+VL N A G
Sbjct: 75 DVDEKNQMMTTNVWVKQEWHDYKLRWDPADYENVTSIRIPSELIWRPDIVLYNNAD---G 131
Query: 406 DYAL----RARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDF 573
D+A+ +A + ++G V W + S+ + +P D Q CT KFGS ++ ++D
Sbjct: 132 DFAVTHLTKAHLFHDGRVQWTPPAIYKSSCSIDVTFFPFDQQNCTMKFGSWTYDKAKIDL 191
Query: 574 V 576
V
Sbjct: 192 V 192
>U62433-1|AAB40111.1| 627|Homo sapiens nicotinic acetylcholine
receptor alpha4 subunit precursor protein.
Length = 627
Score = 62.9 bits (146), Expect = 2e-09
Identities = 50/181 (27%), Positives = 89/181 (49%), Gaps = 11/181 (6%)
Frame = +1
Query: 67 LLPFLLTCAIASAAECEN-ATSLSLMIDSLLATYDRDSPPDSKI--VVNLTLHLRHA--- 228
LL L T + +++ E A + ++ L + Y++ S P + I VV + L A
Sbjct: 15 LLLLLGTGLLRASSHVETRAHAEERLLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLI 74
Query: 229 NIRESESTVRIQADLQMNWIDKRLSWNVGEWGCSTWL-VSSERLWRPDVVLLNAAATTAG 405
++ E + ++ W D +L W+ ++ T + + SE +WRPD+VL N A G
Sbjct: 75 DVDEKNQMMTTNVWVKQEWHDYKLRWDPADYENVTSIRIPSELIWRPDIVLYNNAD---G 131
Query: 406 DYAL----RARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDF 573
D+A+ +A + ++G V W + S+ + +P D Q CT KFGS ++ ++D
Sbjct: 132 DFAVTHLTKAHLFHDGRVQWTPPAIYKSSCSIDVTFFPFDQQNCTMKFGSWTYDKAKIDL 191
Query: 574 V 576
V
Sbjct: 192 V 192
>L35901-1|AAA64743.1| 627|Homo sapiens nicotinic acetylcholine
receptor alpha 4 subunit protein.
Length = 627
Score = 62.9 bits (146), Expect = 2e-09
Identities = 50/181 (27%), Positives = 89/181 (49%), Gaps = 11/181 (6%)
Frame = +1
Query: 67 LLPFLLTCAIASAAECEN-ATSLSLMIDSLLATYDRDSPPDSKI--VVNLTLHLRHA--- 228
LL L T + +++ E A + ++ L + Y++ S P + I VV + L A
Sbjct: 15 LLLLLGTGLLRASSHVETRAHAEERLLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLI 74
Query: 229 NIRESESTVRIQADLQMNWIDKRLSWNVGEWGCSTWL-VSSERLWRPDVVLLNAAATTAG 405
++ E + ++ W D +L W+ ++ T + + SE +WRPD+VL N A G
Sbjct: 75 DVDEKNQMMTTNVWVKQEWHDYKLRWDPADYENVTSIRIPSELIWRPDIVLYNNAD---G 131
Query: 406 DYAL----RARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDF 573
D+A+ +A + ++G V W + S+ + +P D Q CT KFGS ++ ++D
Sbjct: 132 DFAVTHLTKAHLFHDGRVQWTPPAIYKSSCSIDVTFFPFDQQNCTMKFGSWTYDKAKIDL 191
Query: 574 V 576
V
Sbjct: 192 V 192
>DQ093071-1|AAY88737.1| 627|Homo sapiens cholinergic receptor,
nicotinic, alpha polypeptide 4 protein.
Length = 627
Score = 62.9 bits (146), Expect = 2e-09
Identities = 50/181 (27%), Positives = 89/181 (49%), Gaps = 11/181 (6%)
Frame = +1
Query: 67 LLPFLLTCAIASAAECEN-ATSLSLMIDSLLATYDRDSPPDSKI--VVNLTLHLRHA--- 228
LL L T + +++ E A + ++ L + Y++ S P + I VV + L A
Sbjct: 15 LLLLLGTGLLRASSHVETRAHAEERLLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLI 74
Query: 229 NIRESESTVRIQADLQMNWIDKRLSWNVGEWGCSTWL-VSSERLWRPDVVLLNAAATTAG 405
++ E + ++ W D +L W+ ++ T + + SE +WRPD+VL N A G
Sbjct: 75 DVDEKNQMMTTNVWVKQEWHDYKLRWDPADYENVTSIRIPSELIWRPDIVLYNNAD---G 131
Query: 406 DYAL----RARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDF 573
D+A+ +A + ++G V W + S+ + +P D Q CT KFGS ++ ++D
Sbjct: 132 DFAVTHLTKAHLFHDGRVQWTPPAIYKSSCSIDVTFFPFDQQNCTMKFGSWTYDKAKIDL 191
Query: 574 V 576
V
Sbjct: 192 V 192
>BC096290-1|AAH96290.1| 627|Homo sapiens cholinergic receptor,
nicotinic, alpha 4 protein.
Length = 627
Score = 62.9 bits (146), Expect = 2e-09
Identities = 50/181 (27%), Positives = 89/181 (49%), Gaps = 11/181 (6%)
Frame = +1
Query: 67 LLPFLLTCAIASAAECEN-ATSLSLMIDSLLATYDRDSPPDSKI--VVNLTLHLRHA--- 228
LL L T + +++ E A + ++ L + Y++ S P + I VV + L A
Sbjct: 15 LLLLLGTGLLRASSHVETRAHAEERLLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLI 74
Query: 229 NIRESESTVRIQADLQMNWIDKRLSWNVGEWGCSTWL-VSSERLWRPDVVLLNAAATTAG 405
++ E + ++ W D +L W+ ++ T + + SE +WRPD+VL N A G
Sbjct: 75 DVDEKNQMMTTNVWVKQEWHDYKLRWDPADYENVTSIRIPSELIWRPDIVLYNNAD---G 131
Query: 406 DYAL----RARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDF 573
D+A+ +A + ++G V W + S+ + +P D Q CT KFGS ++ ++D
Sbjct: 132 DFAVTHLTKAHLFHDGRVQWTPPAIYKSSCSIDVTFFPFDQQNCTMKFGSWTYDKAKIDL 191
Query: 574 V 576
V
Sbjct: 192 V 192
>BC023553-1|AAH23553.1| 501|Homo sapiens cholinergic receptor,
nicotinic, beta 1 (muscle) protein.
Length = 501
Score = 62.9 bits (146), Expect = 2e-09
Identities = 43/132 (32%), Positives = 69/132 (52%), Gaps = 6/132 (4%)
Frame = +1
Query: 190 KIVVNLTL-HLRHANIRESESTVRIQADLQMNWIDKRLSWNVGEW-GCSTWLVSSERLWR 363
++ V L L L N ++ E + ++ DL+ W D RLSW+ E G + +++E +W
Sbjct: 53 RVSVGLILAQLISLNEKDEEMSTKVYLDLE--WTDYRLSWDPAEHDGIDSLRITAESVWL 110
Query: 364 PDVVLLNAAATTAGDY----ALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTF 531
PDVVLLN G++ + VS++GSV W + S+Q+ +P D Q CT
Sbjct: 111 PDVVLLN---NNDGNFYVALDISVVVSSDGSVRWQPPGIYRSSCSIQVTYFPFDWQNCTM 167
Query: 532 KFGSRMHNSDEM 567
F S ++S E+
Sbjct: 168 VFSSYSYDSSEV 179
>X87629-1|CAA60959.1| 602|Homo sapiens nicotinic acetylcholine
receptor protein.
Length = 602
Score = 62.5 bits (145), Expect = 2e-09
Identities = 44/156 (28%), Positives = 78/156 (50%), Gaps = 10/156 (6%)
Frame = +1
Query: 139 MIDSLLATYDRDSPPDSKI--VVNLTLHLRHA---NIRESESTVRIQADLQMNWIDKRLS 303
++ L + Y++ S P + I VV + L A ++ E + ++ W D +L
Sbjct: 15 LLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLR 74
Query: 304 WNVGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNGSVSWIKRLD 468
W+ ++ T + + SE +WRPD+VL N A GD+A+ +A + ++G V W
Sbjct: 75 WDPADYENVTSIRIPSELIWRPDIVLYNNAD---GDFAVTHLTKAHLFHDGRVQWTPPAI 131
Query: 469 ISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFV 576
+ S+ + +P D Q CT KFGS ++ ++D V
Sbjct: 132 YKSSCSIDVTFFPFDQQNCTMKFGSWTYDKAKIDLV 167
>AJ001935-1|CAA05108.1| 504|Homo sapiens CHRNB2 protein.
Length = 504
Score = 62.5 bits (145), Expect = 2e-09
Identities = 50/182 (27%), Positives = 81/182 (44%), Gaps = 6/182 (3%)
Frame = +1
Query: 64 ILLPF--LLTCAIASAAECENATSLSLMIDSLLATYDRDSPPDSKIV-VNLTLHLRHA-N 231
+LL F L C+ A+ E L+ S R + S++V V L + L +
Sbjct: 10 LLLGFGLLRLCSGVWGADTEERLVEHLLDPSRYNKLIRPATNGSELVTVQLMVSLAQLIS 69
Query: 232 IRESESTVRIQADLQMNWIDKRLSWNVGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAG 405
+ E E + L W D RL+W E+ + S+ +W PDVVL N A
Sbjct: 70 VHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLPDVVLYNNADGMYEV 129
Query: 406 DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDQ 585
+ A VS +GS+ W+ + +++ ++P D Q CT KF S ++ E+D V+
Sbjct: 130 SFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRSWTYDRTEIDLVLKS 189
Query: 586 RI 591
+
Sbjct: 190 EV 191
>Y08415-1|CAA69692.1| 502|Homo sapiens nicotinic acetylcholine
receptor beta2 subunit precursor protein.
Length = 502
Score = 62.1 bits (144), Expect = 3e-09
Identities = 38/136 (27%), Positives = 63/136 (46%), Gaps = 3/136 (2%)
Frame = +1
Query: 193 IVVNLTLHLRHA-NIRESESTVRIQADLQMNWIDKRLSWNVGEW-GCSTWLVSSERLWRP 366
+ V L + L ++ E E + L W D RL+W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 367 DVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 543
DVVL N A + A VS +GS+ W+ + +++ ++P D Q CT KF S
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRS 175
Query: 544 RMHNSDEMDFVIDQRI 591
++ E+D V+ +
Sbjct: 176 WTYDRTEIDLVLKSEV 191
>Y00762-1|CAA68731.1| 457|Homo sapiens protein ( Human mRNA for
muscle acetylcholine receptor alpha-subunit. ).
Length = 457
Score = 62.1 bits (144), Expect = 3e-09
Identities = 44/167 (26%), Positives = 77/167 (46%), Gaps = 10/167 (5%)
Frame = +1
Query: 73 PFLLTCAIASAAECENATSLSLMIDSLLATYDRDSPP--DSKIVVNLTLHLRHA---NIR 237
P LL ++ SA + + ++ L Y P D + VV +T+ L+ N+
Sbjct: 5 PLLLLFSLCSAGLVLGSEHETRLVAKLFKDYSSVVRPVEDHRQVVEVTVGLQLIQLINVD 64
Query: 238 ESESTVRIQADLQMNWIDKRLSWNVGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYA 414
E V L+ W+D L WN ++G + + SE++WRPD+VL N A GD+A
Sbjct: 65 EVNQIVTTNVRLKQQWVDYNLKWNPDDYGGVKKIHIPSEKIWRPDLVLYNNA---DGDFA 121
Query: 415 L----RARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 543
+ + + G ++W + + + ++P D Q C+ K G+
Sbjct: 122 IVKFTKVLLQYTGHITWTPPAIFKSYCEIIVTHFPFDEQNCSMKLGT 168
>X53179-1|CAA37320.1| 502|Homo sapiens precursor peptide (AA -25 to
477) protein.
Length = 502
Score = 62.1 bits (144), Expect = 3e-09
Identities = 38/136 (27%), Positives = 63/136 (46%), Gaps = 3/136 (2%)
Frame = +1
Query: 193 IVVNLTLHLRHA-NIRESESTVRIQADLQMNWIDKRLSWNVGEW-GCSTWLVSSERLWRP 366
+ V L + L ++ E E + L W D RL+W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 367 DVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 543
DVVL N A + A VS +GS+ W+ + +++ ++P D Q CT KF S
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRS 175
Query: 544 RMHNSDEMDFVIDQRI 591
++ E+D V+ +
Sbjct: 176 WTYDRTEIDLVLKSEV 191
>X02502-1|CAA26344.1| 457|Homo sapiens acetylcholine receptor
protein.
Length = 457
Score = 62.1 bits (144), Expect = 3e-09
Identities = 44/167 (26%), Positives = 77/167 (46%), Gaps = 10/167 (5%)
Frame = +1
Query: 73 PFLLTCAIASAAECENATSLSLMIDSLLATYDRDSPP--DSKIVVNLTLHLRHA---NIR 237
P LL ++ SA + + ++ L Y P D + VV +T+ L+ N+
Sbjct: 5 PLLLLFSLCSAGLVLGSEHETRLVAKLFKDYSSVVRPVEDHRQVVEVTVGLQLIQLINVD 64
Query: 238 ESESTVRIQADLQMNWIDKRLSWNVGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYA 414
E V L+ W+D L WN ++G + + SE++WRPD+VL N A GD+A
Sbjct: 65 EVNQIVTTNVRLKQQWVDYNLKWNPDDYGGVKKIHIPSEKIWRPDLVLYNNA---DGDFA 121
Query: 415 L----RARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 543
+ + + G ++W + + + ++P D Q C+ K G+
Sbjct: 122 IVKFTKVLLQYTGHITWTPPAIFKSYCEIIVTHFPFDEQNCSMKLGT 168
>U62437-1|AAB40115.1| 502|Homo sapiens nicotinic acetylcholine
receptor beta2 subunit precursor protein.
Length = 502
Score = 62.1 bits (144), Expect = 3e-09
Identities = 38/136 (27%), Positives = 63/136 (46%), Gaps = 3/136 (2%)
Frame = +1
Query: 193 IVVNLTLHLRHA-NIRESESTVRIQADLQMNWIDKRLSWNVGEW-GCSTWLVSSERLWRP 366
+ V L + L ++ E E + L W D RL+W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 367 DVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 543
DVVL N A + A VS +GS+ W+ + +++ ++P D Q CT KF S
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRS 175
Query: 544 RMHNSDEMDFVIDQRI 591
++ E+D V+ +
Sbjct: 176 WTYDRTEIDLVLKSEV 191
>S77094-1|AAD14247.1| 457|Homo sapiens nicotinic acetylcholine
receptor alpha subunit|AChR protein.
Length = 457
Score = 62.1 bits (144), Expect = 3e-09
Identities = 44/167 (26%), Positives = 77/167 (46%), Gaps = 10/167 (5%)
Frame = +1
Query: 73 PFLLTCAIASAAECENATSLSLMIDSLLATYDRDSPP--DSKIVVNLTLHLRHA---NIR 237
P LL ++ SA + + ++ L Y P D + VV +T+ L+ N+
Sbjct: 5 PLLLLFSLCSAGLVLGSEHETRLVAKLFKDYSSVVRPVEDHRQVVEVTVGLQLIQLINVD 64
Query: 238 ESESTVRIQADLQMNWIDKRLSWNVGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYA 414
E V L+ W+D L WN ++G + + SE++WRPD+VL N A GD+A
Sbjct: 65 EVNQIVTTNVRLKQQWVDYNLKWNPDDYGGVKKIHIPSEKIWRPDLVLYNNA---DGDFA 121
Query: 415 L----RARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 543
+ + + G ++W + + + ++P D Q C+ K G+
Sbjct: 122 IVKFTKVLLQYTGHITWTPPAIFKSYCEIIVTHFPFDEQNCSMKLGT 168
>BC075041-1|AAH75041.1| 502|Homo sapiens cholinergic receptor,
nicotinic, beta 2 (neuronal) protein.
Length = 502
Score = 62.1 bits (144), Expect = 3e-09
Identities = 38/136 (27%), Positives = 63/136 (46%), Gaps = 3/136 (2%)
Frame = +1
Query: 193 IVVNLTLHLRHA-NIRESESTVRIQADLQMNWIDKRLSWNVGEW-GCSTWLVSSERLWRP 366
+ V L + L ++ E E + L W D RL+W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 367 DVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 543
DVVL N A + A VS +GS+ W+ + +++ ++P D Q CT KF S
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRS 175
Query: 544 RMHNSDEMDFVIDQRI 591
++ E+D V+ +
Sbjct: 176 WTYDRTEIDLVLKSEV 191
>BC075040-1|AAH75040.1| 502|Homo sapiens cholinergic receptor,
nicotinic, beta 2 (neuronal) protein.
Length = 502
Score = 62.1 bits (144), Expect = 3e-09
Identities = 38/136 (27%), Positives = 63/136 (46%), Gaps = 3/136 (2%)
Frame = +1
Query: 193 IVVNLTLHLRHA-NIRESESTVRIQADLQMNWIDKRLSWNVGEW-GCSTWLVSSERLWRP 366
+ V L + L ++ E E + L W D RL+W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 367 DVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 543
DVVL N A + A VS +GS+ W+ + +++ ++P D Q CT KF S
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRS 175
Query: 544 RMHNSDEMDFVIDQRI 591
++ E+D V+ +
Sbjct: 176 WTYDRTEIDLVLKSEV 191
>BC006314-1|AAH06314.1| 269|Homo sapiens CHRNA1 protein protein.
Length = 269
Score = 62.1 bits (144), Expect = 3e-09
Identities = 44/167 (26%), Positives = 77/167 (46%), Gaps = 10/167 (5%)
Frame = +1
Query: 73 PFLLTCAIASAAECENATSLSLMIDSLLATYDRDSPP--DSKIVVNLTLHLRHA---NIR 237
P LL ++ SA + + ++ L Y P D + VV +T+ L+ N+
Sbjct: 5 PLLLLFSLCSAGLVLGSEHETRLVAKLFKDYSSVVRPVEDHRQVVEVTVGLQLIQLINVD 64
Query: 238 ESESTVRIQADLQMNWIDKRLSWNVGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYA 414
E V L+ W+D L WN ++G + + SE++WRPD+VL N A GD+A
Sbjct: 65 EVNQIVTTNVRLKQQWVDYNLKWNPDDYGGVKKIHIPSEKIWRPDLVLYNNA---DGDFA 121
Query: 415 L----RARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 543
+ + + G ++W + + + ++P D Q C+ K G+
Sbjct: 122 IVKFTKVLLQYTGHITWTPPAIFKSYCEIIVTHFPFDEQNCSMKLGT 168
>AL592078-3|CAI16184.1| 502|Homo sapiens cholinergic receptor,
nicotinic, beta 2 (neuronal) protein.
Length = 502
Score = 62.1 bits (144), Expect = 3e-09
Identities = 38/136 (27%), Positives = 63/136 (46%), Gaps = 3/136 (2%)
Frame = +1
Query: 193 IVVNLTLHLRHA-NIRESESTVRIQADLQMNWIDKRLSWNVGEW-GCSTWLVSSERLWRP 366
+ V L + L ++ E E + L W D RL+W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 367 DVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 543
DVVL N A + A VS +GS+ W+ + +++ ++P D Q CT KF S
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRS 175
Query: 544 RMHNSDEMDFVIDQRI 591
++ E+D V+ +
Sbjct: 176 WTYDRTEIDLVLKSEV 191
>AF077186-1|AAD45422.1| 502|Homo sapiens neuronal nicotinic
acetylcholine receptor beta 2 protein.
Length = 502
Score = 62.1 bits (144), Expect = 3e-09
Identities = 38/136 (27%), Positives = 63/136 (46%), Gaps = 3/136 (2%)
Frame = +1
Query: 193 IVVNLTLHLRHA-NIRESESTVRIQADLQMNWIDKRLSWNVGEW-GCSTWLVSSERLWRP 366
+ V L + L ++ E E + L W D RL+W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 367 DVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 543
DVVL N A + A VS +GS+ W+ + +++ ++P D Q CT KF S
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRS 175
Query: 544 RMHNSDEMDFVIDQRI 591
++ E+D V+ +
Sbjct: 176 WTYDRTEIDLVLKSEV 191
>AC018890-1|AAY14687.1| 457|Homo sapiens unknown protein.
Length = 457
Score = 62.1 bits (144), Expect = 3e-09
Identities = 44/167 (26%), Positives = 77/167 (46%), Gaps = 10/167 (5%)
Frame = +1
Query: 73 PFLLTCAIASAAECENATSLSLMIDSLLATYDRDSPP--DSKIVVNLTLHLRHA---NIR 237
P LL ++ SA + + ++ L Y P D + VV +T+ L+ N+
Sbjct: 5 PLLLLFSLCSAGLVLGSEHETRLVAKLFKDYSSVVRPVEDHRQVVEVTVGLQLIQLINVD 64
Query: 238 ESESTVRIQADLQMNWIDKRLSWNVGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYA 414
E V L+ W+D L WN ++G + + SE++WRPD+VL N A GD+A
Sbjct: 65 EVNQIVTTNVRLKQQWVDYNLKWNPDDYGGVKKIHIPSEKIWRPDLVLYNNA---DGDFA 121
Query: 415 L----RARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 543
+ + + G ++W + + + ++P D Q C+ K G+
Sbjct: 122 IVKFTKVLLQYTGHITWTPPAIFKSYCEIIVTHFPFDEQNCSMKLGT 168
>AJ295237-1|CAC16144.1| 450|Homo sapiens neuronal nicotinic
acetylcholine receptor subunit4 protein.
Length = 450
Score = 58.0 bits (134), Expect = 4e-08
Identities = 48/176 (27%), Positives = 75/176 (42%), Gaps = 7/176 (3%)
Frame = +1
Query: 64 ILLPFLLTCAIASAAECENATSLSLMIDSLLATYDRDSPP--DSKIVVNLTLHLRHANI- 234
+LL FLL A E +L L D L A Y P D+ +N+TL + + I
Sbjct: 12 LLLLFLLPAECLGA---EGRLALKLFRD-LFANYTSALRPVADTDQTLNVTLEVTLSQII 67
Query: 235 --RESESTVRIQADLQMNWIDKRLSWNVGEWG-CSTWLVSSERLWRPDVVLLNAA-ATTA 402
E + + ++ W D L W+ +G + S +WRPD+VL N A A
Sbjct: 68 DMDERNQVLTLYLWIRQEWTDAYLRWDPNAYGGLDAIRIPSSLVWRPDIVLYNKADAQPP 127
Query: 403 GDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 570
G + + ++G+V W + + + +P D Q C FGS H ++D
Sbjct: 128 GSASTNVVLRHDGAVRWDAPAITRSSCRVDVAAFPFDAQHCGLTFGSWTHGGHQLD 183
>AJ278118-1|CAC20435.1| 450|Homo sapiens neuronal nicotinic
acetylcholine alpha10 subunit protein.
Length = 450
Score = 58.0 bits (134), Expect = 4e-08
Identities = 48/176 (27%), Positives = 75/176 (42%), Gaps = 7/176 (3%)
Frame = +1
Query: 64 ILLPFLLTCAIASAAECENATSLSLMIDSLLATYDRDSPP--DSKIVVNLTLHLRHANI- 234
+LL FLL A E +L L D L A Y P D+ +N+TL + + I
Sbjct: 12 LLLLFLLPAECLGA---EGRLALKLFRD-LFANYTSALRPVADTDQTLNVTLEVTLSQII 67
Query: 235 --RESESTVRIQADLQMNWIDKRLSWNVGEWG-CSTWLVSSERLWRPDVVLLNAA-ATTA 402
E + + ++ W D L W+ +G + S +WRPD+VL N A A
Sbjct: 68 DMDERNQVLTLYLWIRQEWTDAYLRWDPNAYGGLDAIRIPSSLVWRPDIVLYNKADAQPP 127
Query: 403 GDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 570
G + + ++G+V W + + + +P D Q C FGS H ++D
Sbjct: 128 GSASTNVVLRHDGAVRWDAPAITRSSCRVDVAAFPFDAQHCGLTFGSWTHGGHQLD 183
>AF327367-1|AAK14333.1| 450|Homo sapiens nicotinic acetylcholine
receptor subunit alpha 10 protein.
Length = 450
Score = 58.0 bits (134), Expect = 4e-08
Identities = 48/176 (27%), Positives = 75/176 (42%), Gaps = 7/176 (3%)
Frame = +1
Query: 64 ILLPFLLTCAIASAAECENATSLSLMIDSLLATYDRDSPP--DSKIVVNLTLHLRHANI- 234
+LL FLL A E +L L D L A Y P D+ +N+TL + + I
Sbjct: 12 LLLLFLLPAECLGA---EGRLALKLFRD-LFANYTSALRPVADTDQTLNVTLEVTLSQII 67
Query: 235 --RESESTVRIQADLQMNWIDKRLSWNVGEWG-CSTWLVSSERLWRPDVVLLNAA-ATTA 402
E + + ++ W D L W+ +G + S +WRPD+VL N A A
Sbjct: 68 DMDERNQVLTLYLWIRQEWTDAYLRWDPNAYGGLDAIRIPSSLVWRPDIVLYNKADAQPP 127
Query: 403 GDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 570
G + + ++G+V W + + + +P D Q C FGS H ++D
Sbjct: 128 GSASTNVVLRHDGAVRWDAPAITRSSCRVDVAAFPFDAQHCGLTFGSWTHGGHQLD 183
>AF199235-1|AAG00795.2| 450|Homo sapiens nicotinic acetylcholine
receptor subunit alpha 10 protein.
Length = 450
Score = 58.0 bits (134), Expect = 4e-08
Identities = 48/176 (27%), Positives = 75/176 (42%), Gaps = 7/176 (3%)
Frame = +1
Query: 64 ILLPFLLTCAIASAAECENATSLSLMIDSLLATYDRDSPP--DSKIVVNLTLHLRHANI- 234
+LL FLL A E +L L D L A Y P D+ +N+TL + + I
Sbjct: 12 LLLLFLLPAECLGA---EGRLALKLFRD-LFANYTSALRPVADTDQTLNVTLEVTLSQII 67
Query: 235 --RESESTVRIQADLQMNWIDKRLSWNVGEWG-CSTWLVSSERLWRPDVVLLNAA-ATTA 402
E + + ++ W D L W+ +G + S +WRPD+VL N A A
Sbjct: 68 DMDERNQVLTLYLWIRQEWTDAYLRWDPNAYGGLDAIRIPSSLVWRPDIVLYNKADAQPP 127
Query: 403 GDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 570
G + + ++G+V W + + + +P D Q C FGS H ++D
Sbjct: 128 GSASTNVVLRHDGAVRWDAPAITRSSCRVDVAAFPFDAQHCGLTFGSWTHGGHQLD 183
>DQ644022-1|ABG35128.1| 456|Homo sapiens 5-HT3 receptor subunit E
splice variant HTR3Ea protein.
Length = 456
Score = 57.2 bits (132), Expect = 8e-08
Identities = 28/114 (24%), Positives = 58/114 (50%), Gaps = 1/114 (0%)
Frame = +1
Query: 271 LQMNWIDKRLSWNVGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 447
L+M W + +SWN E G + ++++ LW PD+ ++ L A VSN G +
Sbjct: 91 LEMVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEGRI 150
Query: 448 SWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDQRIYXMFES 609
+ K + + + ++ + +P D Q CT F S ++ D M +++ ++ + ++
Sbjct: 151 RYKKPMKVDSICNLDIFYFPFDQQNCTLTFSSFLYTVDSMLLDMEKEVWEITDA 204
>BC131799-1|AAI31800.1| 447|Homo sapiens 5-hydroxytryptamine
(serotonin) receptor 3, family member C protein.
Length = 447
Score = 57.2 bits (132), Expect = 8e-08
Identities = 27/114 (23%), Positives = 59/114 (51%), Gaps = 1/114 (0%)
Frame = +1
Query: 271 LQMNWIDKRLSWNVGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 447
+ + W + ++WN E G + V +E LW PD+ ++ + L A +S+ G +
Sbjct: 91 MDLVWDNPFINWNPKECVGINKLTVLAENLWLPDIFIVESMDVDQTPSGLTAYISSEGRI 150
Query: 448 SWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDQRIYXMFES 609
+ K + +++ ++ + +P D Q CTF F S ++ D M +D+ ++ + ++
Sbjct: 151 KYDKPMRVTSICNLDIFYFPFDQQNCTFTFSSFLYTVDSMLLGMDKEVWEITDT 204
>BC101185-1|AAI01186.1| 374|Homo sapiens HTR3E protein protein.
Length = 374
Score = 57.2 bits (132), Expect = 8e-08
Identities = 28/114 (24%), Positives = 58/114 (50%), Gaps = 1/114 (0%)
Frame = +1
Query: 271 LQMNWIDKRLSWNVGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 447
L+M W + +SWN E G + ++++ LW PD+ ++ L A VSN G +
Sbjct: 20 LEMVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEGRI 79
Query: 448 SWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDQRIYXMFES 609
+ K + + + ++ + +P D Q CT F S ++ D M +++ ++ + ++
Sbjct: 80 RYKKPMKVDSICNLDIFYFPFDQQNCTLTFSSFLYTVDSMLLDMEKEVWEITDA 133
>BC101183-1|AAI01184.1| 471|Homo sapiens 5-hydroxytryptamine
(serotonin) receptor 3, family member E protein.
Length = 471
Score = 57.2 bits (132), Expect = 8e-08
Identities = 28/114 (24%), Positives = 58/114 (50%), Gaps = 1/114 (0%)
Frame = +1
Query: 271 LQMNWIDKRLSWNVGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 447
L+M W + +SWN E G + ++++ LW PD+ ++ L A VSN G +
Sbjct: 106 LEMVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEGRI 165
Query: 448 SWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDQRIYXMFES 609
+ K + + + ++ + +P D Q CT F S ++ D M +++ ++ + ++
Sbjct: 166 RYKKPMKVDSICNLDIFYFPFDQQNCTLTFSSFLYTVDSMLLDMEKEVWEITDA 219
>BC101182-1|AAI01183.1| 471|Homo sapiens 5-hydroxytryptamine
(serotonin) receptor 3, family member E protein.
Length = 471
Score = 57.2 bits (132), Expect = 8e-08
Identities = 28/114 (24%), Positives = 58/114 (50%), Gaps = 1/114 (0%)
Frame = +1
Query: 271 LQMNWIDKRLSWNVGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 447
L+M W + +SWN E G + ++++ LW PD+ ++ L A VSN G +
Sbjct: 106 LEMVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEGRI 165
Query: 448 SWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDQRIYXMFES 609
+ K + + + ++ + +P D Q CT F S ++ D M +++ ++ + ++
Sbjct: 166 RYKKPMKVDSICNLDIFYFPFDQQNCTLTFSSFLYTVDSMLLDMEKEVWEITDA 219
>AY159813-1|AAO38167.2| 471|Homo sapiens 5-hydroxytryptamine
serotonin receptor 3E protein.
Length = 471
Score = 57.2 bits (132), Expect = 8e-08
Identities = 28/114 (24%), Positives = 58/114 (50%), Gaps = 1/114 (0%)
Frame = +1
Query: 271 LQMNWIDKRLSWNVGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 447
L+M W + +SWN E G + ++++ LW PD+ ++ L A VSN G +
Sbjct: 106 LEMVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEGRI 165
Query: 448 SWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDQRIYXMFES 609
+ K + + + ++ + +P D Q CT F S ++ D M +++ ++ + ++
Sbjct: 166 RYKKPMKVDSICNLDIFYFPFDQQNCTLTFSSFLYTVDSMLLDMEKEVWEITDA 219
>X55019-1|CAA38759.1| 517|Homo sapiens acetylcholine receptor delta
subunit protein.
Length = 517
Score = 56.8 bits (131), Expect = 1e-07
Identities = 35/137 (25%), Positives = 63/137 (45%), Gaps = 3/137 (2%)
Frame = +1
Query: 184 DSKIVVNLTLHLRHA-NIRESESTVRIQADLQMNWIDKRLSWNVGEWG-CSTWLVSSERL 357
+ + V L L L + +++E E T+ ++ W D RL WN E+G S + + +
Sbjct: 49 EESVDVALALTLSNLISLKEVEETLTTNVWIEHGWTDNRLKWNAEEFGNISVLRLPPDMV 108
Query: 358 WRPDVVL-LNAAATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFK 534
W P++VL N + Y+ V + G V W+ + + + +P D Q C+ K
Sbjct: 109 WLPEIVLENNNDGSFQISYSCNVLVYHYGFVYWLPPAIFRSSCPISVTYFPFDWQNCSLK 168
Query: 535 FGSRMHNSDEMDFVIDQ 585
F S + + E+ + Q
Sbjct: 169 FSSLKYTAKEITLSLKQ 185
>BC093925-1|AAH93925.1| 517|Homo sapiens cholinergic receptor,
nicotinic, delta protein.
Length = 517
Score = 56.8 bits (131), Expect = 1e-07
Identities = 35/137 (25%), Positives = 63/137 (45%), Gaps = 3/137 (2%)
Frame = +1
Query: 184 DSKIVVNLTLHLRHA-NIRESESTVRIQADLQMNWIDKRLSWNVGEWG-CSTWLVSSERL 357
+ + V L L L + +++E E T+ ++ W D RL WN E+G S + + +
Sbjct: 49 EESVDVALALTLSNLISLKEVEETLTTNVWIEHGWTDNRLKWNAEEFGNISVLRLPPDMV 108
Query: 358 WRPDVVL-LNAAATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFK 534
W P++VL N + Y+ V + G V W+ + + + +P D Q C+ K
Sbjct: 109 WLPEIVLENNNDGSFQISYSCNVLVYHYGFVYWLPPAIFRSSCPISVTYFPFDWQNCSLK 168
Query: 535 FGSRMHNSDEMDFVIDQ 585
F S + + E+ + Q
Sbjct: 169 FSSLKYTAKEITLSLKQ 185
>BC093923-1|AAH93923.1| 517|Homo sapiens cholinergic receptor,
nicotinic, delta protein.
Length = 517
Score = 56.8 bits (131), Expect = 1e-07
Identities = 35/137 (25%), Positives = 63/137 (45%), Gaps = 3/137 (2%)
Frame = +1
Query: 184 DSKIVVNLTLHLRHA-NIRESESTVRIQADLQMNWIDKRLSWNVGEWG-CSTWLVSSERL 357
+ + V L L L + +++E E T+ ++ W D RL WN E+G S + + +
Sbjct: 49 EESVDVALALTLSNLISLKEVEETLTTNVWIEHGWTDNRLKWNAEEFGNISVLRLPPDMV 108
Query: 358 WRPDVVL-LNAAATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFK 534
W P++VL N + Y+ V + G V W+ + + + +P D Q C+ K
Sbjct: 109 WLPEIVLENNNDGSFQISYSCNVLVYHYGFVYWLPPAIFRSSCPISVTYFPFDWQNCSLK 168
Query: 535 FGSRMHNSDEMDFVIDQ 585
F S + + E+ + Q
Sbjct: 169 FSSLKYTAKEITLSLKQ 185
>AF459285-1|AAL66182.1| 447|Homo sapiens 5-hydroxytryptamine
receptor 3 subunit C protein.
Length = 447
Score = 56.8 bits (131), Expect = 1e-07
Identities = 27/114 (23%), Positives = 58/114 (50%), Gaps = 1/114 (0%)
Frame = +1
Query: 271 LQMNWIDKRLSWNVGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 447
+ + W + ++WN E G + V +E LW PD+ ++ + L A +S+ G +
Sbjct: 91 MDLVWDNPFINWNPKECVGINKLTVLAENLWLPDIFIVESMDVDQTPSGLTAYISSEGRI 150
Query: 448 SWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDQRIYXMFES 609
+ K + +++ + + +P D Q CTF F S ++ D M +D+ ++ + ++
Sbjct: 151 KYDKPMRVTSICKLDIFYFPFDQQNCTFTFSSFLYTVDSMLLGMDKEVWEITDT 204
>AC092165-2|AAY24102.1| 517|Homo sapiens unknown protein.
Length = 517
Score = 56.8 bits (131), Expect = 1e-07
Identities = 35/137 (25%), Positives = 63/137 (45%), Gaps = 3/137 (2%)
Frame = +1
Query: 184 DSKIVVNLTLHLRHA-NIRESESTVRIQADLQMNWIDKRLSWNVGEWG-CSTWLVSSERL 357
+ + V L L L + +++E E T+ ++ W D RL WN E+G S + + +
Sbjct: 49 EESVDVALALTLSNLISLKEVEETLTTNVWIEHGWTDNRLKWNAEEFGNISVLRLPPDMV 108
Query: 358 WRPDVVL-LNAAATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFK 534
W P++VL N + Y+ V + G V W+ + + + +P D Q C+ K
Sbjct: 109 WLPEIVLENNNDGSFQISYSCNVLVYHYGFVYWLPPAIFRSSCPISVTYFPFDWQNCSLK 168
Query: 535 FGSRMHNSDEMDFVIDQ 585
F S + + E+ + Q
Sbjct: 169 FSSLKYTAKEITLSLKQ 185
>S77554-1|AAB33983.1| 474|Homo sapiens GABAA receptor beta 2
subunit protein.
Length = 474
Score = 55.6 bits (128), Expect = 2e-07
Identities = 45/182 (24%), Positives = 80/182 (43%), Gaps = 10/182 (5%)
Frame = +1
Query: 58 YIILLPFLLTCAIASAAECENATSLSLM---IDSLLATYDRDSPPD---SKIVVNLTLHL 219
Y + F L A A + +++SL+ +D LL YD PD + V + + +
Sbjct: 9 YFGIWSFPLIIAAVCAQSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDI 68
Query: 220 RHAN-IRESESTVRIQADLQMNWIDKRLSWNVGEWGCSTWLVSSERLWRPDVVLLNAAAT 396
+ + E + Q W DKRLS+NV + +++LW PD LN +
Sbjct: 69 ASIDMVSEVNMDYTLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLNDKKS 128
Query: 397 TAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEM 567
++ R+ +G+V + R+ + M L +P D Q CT + S + +D++
Sbjct: 129 FVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDI 188
Query: 568 DF 573
+F
Sbjct: 189 EF 190
>S77553-1|AAB33982.1| 512|Homo sapiens GABAA receptor beta 2
subunit protein.
Length = 512
Score = 55.6 bits (128), Expect = 2e-07
Identities = 45/182 (24%), Positives = 80/182 (43%), Gaps = 10/182 (5%)
Frame = +1
Query: 58 YIILLPFLLTCAIASAAECENATSLSLM---IDSLLATYDRDSPPD---SKIVVNLTLHL 219
Y + F L A A + +++SL+ +D LL YD PD + V + + +
Sbjct: 9 YFGIWSFPLIIAAVCAQSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDI 68
Query: 220 RHAN-IRESESTVRIQADLQMNWIDKRLSWNVGEWGCSTWLVSSERLWRPDVVLLNAAAT 396
+ + E + Q W DKRLS+NV + +++LW PD LN +
Sbjct: 69 ASIDMVSEVNMDYTLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLNDKKS 128
Query: 397 TAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEM 567
++ R+ +G+V + R+ + M L +P D Q CT + S + +D++
Sbjct: 129 FVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDI 188
Query: 568 DF 573
+F
Sbjct: 189 EF 190
>S67368-1|AAB29370.1| 474|Homo sapiens gamma-aminobutyric acid A
receptor beta 2 subunit protein.
Length = 474
Score = 55.6 bits (128), Expect = 2e-07
Identities = 45/182 (24%), Positives = 80/182 (43%), Gaps = 10/182 (5%)
Frame = +1
Query: 58 YIILLPFLLTCAIASAAECENATSLSLM---IDSLLATYDRDSPPD---SKIVVNLTLHL 219
Y + F L A A + +++SL+ +D LL YD PD + V + + +
Sbjct: 9 YFGIWSFPLIIAAVCAQSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDI 68
Query: 220 RHAN-IRESESTVRIQADLQMNWIDKRLSWNVGEWGCSTWLVSSERLWRPDVVLLNAAAT 396
+ + E + Q W DKRLS+NV + +++LW PD LN +
Sbjct: 69 ASIDMVSEVNMDYTLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLNDKKS 128
Query: 397 TAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEM 567
++ R+ +G+V + R+ + M L +P D Q CT + S + +D++
Sbjct: 129 FVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDI 188
Query: 568 DF 573
+F
Sbjct: 189 EF 190
>BC113575-1|AAI13576.1| 479|Homo sapiens cholinergic receptor,
nicotinic, alpha 9 protein.
Length = 479
Score = 55.6 bits (128), Expect = 2e-07
Identities = 38/163 (23%), Positives = 75/163 (46%), Gaps = 7/163 (4%)
Frame = +1
Query: 103 AAECENATSLSLMIDSLLATYDRDSPP--DSKIVVNLTLHLRHANIRESESTVRIQAD-- 270
AAE + + + L Y P D+ V+N+TL + + I++ + +I
Sbjct: 22 AAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQITLSQIKDMDERNQILTAYL 81
Query: 271 -LQMNWIDKRLSWNVGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGD-YALRARVSNNG 441
++ W D L+W+ ++ G + + S+ +WRPD+VL N A + + + +G
Sbjct: 82 WIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKADDESSEPVNTNVVLRYDG 141
Query: 442 SVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 570
++W + + + +P D Q C FGS +N +++D
Sbjct: 142 LITWDAPAITKSSCVVDVTYFPFDNQQCNLTFGSWTYNGNQVD 184
>BC113549-1|AAI13550.1| 479|Homo sapiens cholinergic receptor,
nicotinic, alpha 9 protein.
Length = 479
Score = 55.6 bits (128), Expect = 2e-07
Identities = 38/163 (23%), Positives = 75/163 (46%), Gaps = 7/163 (4%)
Frame = +1
Query: 103 AAECENATSLSLMIDSLLATYDRDSPP--DSKIVVNLTLHLRHANIRESESTVRIQAD-- 270
AAE + + + L Y P D+ V+N+TL + + I++ + +I
Sbjct: 22 AAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQITLSQIKDMDERNQILTAYL 81
Query: 271 -LQMNWIDKRLSWNVGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGD-YALRARVSNNG 441
++ W D L+W+ ++ G + + S+ +WRPD+VL N A + + + +G
Sbjct: 82 WIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKADDESSEPVNTNVVLRYDG 141
Query: 442 SVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 570
++W + + + +P D Q C FGS +N +++D
Sbjct: 142 LITWDAPAITKSSCVVDVTYFPFDNQQCNLTFGSWTYNGNQVD 184
>BC105639-1|AAI05640.1| 474|Homo sapiens GABRB2 protein protein.
Length = 474
Score = 55.6 bits (128), Expect = 2e-07
Identities = 45/182 (24%), Positives = 80/182 (43%), Gaps = 10/182 (5%)
Frame = +1
Query: 58 YIILLPFLLTCAIASAAECENATSLSLM---IDSLLATYDRDSPPD---SKIVVNLTLHL 219
Y + F L A A + +++SL+ +D LL YD PD + V + + +
Sbjct: 9 YFGIWSFPLIIAAVCAQSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDI 68
Query: 220 RHAN-IRESESTVRIQADLQMNWIDKRLSWNVGEWGCSTWLVSSERLWRPDVVLLNAAAT 396
+ + E + Q W DKRLS+NV + +++LW PD LN +
Sbjct: 69 ASIDMVSEVNMDYTLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLNDKKS 128
Query: 397 TAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEM 567
++ R+ +G+V + R+ + M L +P D Q CT + S + +D++
Sbjct: 129 FVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDI 188
Query: 568 DF 573
+F
Sbjct: 189 EF 190
>BC099719-1|AAH99719.1| 474|Homo sapiens GABRB2 protein protein.
Length = 474
Score = 55.6 bits (128), Expect = 2e-07
Identities = 45/182 (24%), Positives = 80/182 (43%), Gaps = 10/182 (5%)
Frame = +1
Query: 58 YIILLPFLLTCAIASAAECENATSLSLM---IDSLLATYDRDSPPD---SKIVVNLTLHL 219
Y + F L A A + +++SL+ +D LL YD PD + V + + +
Sbjct: 9 YFGIWSFPLIIAAVCAQSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDI 68
Query: 220 RHAN-IRESESTVRIQADLQMNWIDKRLSWNVGEWGCSTWLVSSERLWRPDVVLLNAAAT 396
+ + E + Q W DKRLS+NV + +++LW PD LN +
Sbjct: 69 ASIDMVSEVNMDYTLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLNDKKS 128
Query: 397 TAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEM 567
++ R+ +G+V + R+ + M L +P D Q CT + S + +D++
Sbjct: 129 FVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDI 188
Query: 568 DF 573
+F
Sbjct: 189 EF 190
>BC099705-1|AAH99705.1| 474|Homo sapiens GABRB2 protein protein.
Length = 474
Score = 55.6 bits (128), Expect = 2e-07
Identities = 45/182 (24%), Positives = 80/182 (43%), Gaps = 10/182 (5%)
Frame = +1
Query: 58 YIILLPFLLTCAIASAAECENATSLSLM---IDSLLATYDRDSPPD---SKIVVNLTLHL 219
Y + F L A A + +++SL+ +D LL YD PD + V + + +
Sbjct: 9 YFGIWSFPLIIAAVCAQSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDI 68
Query: 220 RHAN-IRESESTVRIQADLQMNWIDKRLSWNVGEWGCSTWLVSSERLWRPDVVLLNAAAT 396
+ + E + Q W DKRLS+NV + +++LW PD LN +
Sbjct: 69 ASIDMVSEVNMDYTLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLNDKKS 128
Query: 397 TAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEM 567
++ R+ +G+V + R+ + M L +P D Q CT + S + +D++
Sbjct: 129 FVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDI 188
Query: 568 DF 573
+F
Sbjct: 189 EF 190
>AY349353-1|AAQ93477.1| 456|Homo sapiens 5-HT3c1 serotonin
receptor-like protein protein.
Length = 456
Score = 55.6 bits (128), Expect = 2e-07
Identities = 28/118 (23%), Positives = 59/118 (50%), Gaps = 1/118 (0%)
Frame = +1
Query: 259 IQADLQMNWIDKRLSWNVGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSN 435
+ A L + W + +SWN E G + ++++ LW PD+ ++ L A VSN
Sbjct: 87 MSAILDVVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSN 146
Query: 436 NGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDQRIYXMFES 609
G + + K + + + ++ + +P D Q CT F S ++ D M +++ ++ + ++
Sbjct: 147 EGRIRYKKPMKVDSICNLDIFYFPFDQQNCTLTFSSFLYTVDSMLLDMEKEVWEITDA 204
>AY349352-1|AAQ93476.1| 441|Homo sapiens 5-HT3c1 serotonin
receptor-like protein protein.
Length = 441
Score = 55.6 bits (128), Expect = 2e-07
Identities = 28/118 (23%), Positives = 59/118 (50%), Gaps = 1/118 (0%)
Frame = +1
Query: 259 IQADLQMNWIDKRLSWNVGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSN 435
+ A L + W + +SWN E G + ++++ LW PD+ ++ L A VSN
Sbjct: 72 MSAILDVVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSN 131
Query: 436 NGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDQRIYXMFES 609
G + + K + + + ++ + +P D Q CT F S ++ D M +++ ++ + ++
Sbjct: 132 EGRIRYKKPMKVDSICNLDIFYFPFDQQNCTLTFSSFLYTVDSMLLDMEKEVWEITDA 189
>AY123244-1|AAM74523.1| 479|Homo sapiens nicotinic acetylcholine
receptor subunit alpha 9 protein.
Length = 479
Score = 55.6 bits (128), Expect = 2e-07
Identities = 38/163 (23%), Positives = 75/163 (46%), Gaps = 7/163 (4%)
Frame = +1
Query: 103 AAECENATSLSLMIDSLLATYDRDSPP--DSKIVVNLTLHLRHANIRESESTVRIQAD-- 270
AAE + + + L Y P D+ V+N+TL + + I++ + +I
Sbjct: 22 AAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQITLSQIKDMDERNQILTAYL 81
Query: 271 -LQMNWIDKRLSWNVGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGD-YALRARVSNNG 441
++ W D L+W+ ++ G + + S+ +WRPD+VL N A + + + +G
Sbjct: 82 WIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKADDESSEPVNTNVVLRYDG 141
Query: 442 SVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 570
++W + + + +P D Q C FGS +N +++D
Sbjct: 142 LITWDAPAITKSSCVVDVTYFPFDNQQCNLTFGSWTYNGNQVD 184
>AJ243342-1|CAB65091.1| 479|Homo sapiens nicotinic acetylcholine
receptor alpha 9 subunit protein.
Length = 479
Score = 55.6 bits (128), Expect = 2e-07
Identities = 38/163 (23%), Positives = 75/163 (46%), Gaps = 7/163 (4%)
Frame = +1
Query: 103 AAECENATSLSLMIDSLLATYDRDSPP--DSKIVVNLTLHLRHANIRESESTVRIQAD-- 270
AAE + + + L Y P D+ V+N+TL + + I++ + +I
Sbjct: 22 AAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQITLSQIKDMDERNQILTAYL 81
Query: 271 -LQMNWIDKRLSWNVGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGD-YALRARVSNNG 441
++ W D L+W+ ++ G + + S+ +WRPD+VL N A + + + +G
Sbjct: 82 WIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKADDESSEPVNTNVVLRYDG 141
Query: 442 SVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 570
++W + + + +P D Q C FGS +N +++D
Sbjct: 142 LITWDAPAITKSSCVVDVTYFPFDNQQCNLTFGSWTYNGNQVD 184
>AF227732-1|AAF61920.1| 470|Homo sapiens nicotinic acetylcholine
receptor alpha 9 subunit protein.
Length = 470
Score = 55.6 bits (128), Expect = 2e-07
Identities = 38/163 (23%), Positives = 75/163 (46%), Gaps = 7/163 (4%)
Frame = +1
Query: 103 AAECENATSLSLMIDSLLATYDRDSPP--DSKIVVNLTLHLRHANIRESESTVRIQAD-- 270
AAE + + + L Y P D+ V+N+TL + + I++ + +I
Sbjct: 16 AAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQITLSQIKDMDERNQILTAYL 75
Query: 271 -LQMNWIDKRLSWNVGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGD-YALRARVSNNG 441
++ W D L+W+ ++ G + + S+ +WRPD+VL N A + + + +G
Sbjct: 76 WIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKADDESSEPVNTNVVLRYDG 135
Query: 442 SVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 570
++W + + + +P D Q C FGS +N +++D
Sbjct: 136 LITWDAPAITKSSCVVDVTYFPFDNQQCNLTFGSWTYNGNQVD 178
>AC118275-1|AAY40986.1| 479|Homo sapiens unknown protein.
Length = 479
Score = 55.6 bits (128), Expect = 2e-07
Identities = 38/163 (23%), Positives = 75/163 (46%), Gaps = 7/163 (4%)
Frame = +1
Query: 103 AAECENATSLSLMIDSLLATYDRDSPP--DSKIVVNLTLHLRHANIRESESTVRIQAD-- 270
AAE + + + L Y P D+ V+N+TL + + I++ + +I
Sbjct: 22 AAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQITLSQIKDMDERNQILTAYL 81
Query: 271 -LQMNWIDKRLSWNVGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGD-YALRARVSNNG 441
++ W D L+W+ ++ G + + S+ +WRPD+VL N A + + + +G
Sbjct: 82 WIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKADDESSEPVNTNVVLRYDG 141
Query: 442 SVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 570
++W + + + +P D Q C FGS +N +++D
Sbjct: 142 LITWDAPAITKSSCVVDVTYFPFDNQQCNLTFGSWTYNGNQVD 184
>Z23141-1|CAA80672.1| 479|Homo sapiens cholinergic receptor,
nicotinic, alpha polypeptide 7 protein.
Length = 479
Score = 54.8 bits (126), Expect = 4e-07
Identities = 36/140 (25%), Positives = 67/140 (47%), Gaps = 2/140 (1%)
Frame = +1
Query: 172 DSPPDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWNVGEW-GCSTWLVSS 348
DS P + + +L+L L+ ++ E + LQM+W D L WNV E+ G T
Sbjct: 24 DSQPLT-VYFSLSL-LQIMDVDEKNQVLTTNIWLQMSWTDHYLQWNVSEYPGVKTVRFPD 81
Query: 349 ERLWRPDVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTC 525
++W+PD++L N+A + V+++G ++ + + + +P D+Q C
Sbjct: 82 GQIWKPDILLYNSADERFDATFHTNVLVNSSGHCQYLPPGIFKSSCYIDVRWFPFDVQHC 141
Query: 526 TFKFGSRMHNSDEMDFVIDQ 585
KFGS + +D + +
Sbjct: 142 KLKFGSWSYGGWSLDLQMQE 161
>Y08420-1|CAA69697.1| 502|Homo sapiens nicotinic acetylcholine
receptor alpha7 subunit precursor protein.
Length = 502
Score = 54.8 bits (126), Expect = 4e-07
Identities = 36/140 (25%), Positives = 67/140 (47%), Gaps = 2/140 (1%)
Frame = +1
Query: 172 DSPPDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWNVGEW-GCSTWLVSS 348
DS P + + +L+L L+ ++ E + LQM+W D L WNV E+ G T
Sbjct: 47 DSQPLT-VYFSLSL-LQIMDVDEKNQVLTTNIWLQMSWTDHYLQWNVSEYPGVKTVRFPD 104
Query: 349 ERLWRPDVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTC 525
++W+PD++L N+A + V+++G ++ + + + +P D+Q C
Sbjct: 105 GQIWKPDILLYNSADERFDATFHTNVLVNSSGHCQYLPPGIFKSSCYIDVRWFPFDVQHC 164
Query: 526 TFKFGSRMHNSDEMDFVIDQ 585
KFGS + +D + +
Sbjct: 165 KLKFGSWSYGGWSLDLQMQE 184
>X70297-1|CAA49778.1| 502|Homo sapiens neuronal nicotinic
acetylocholine receptor alpha-7 subunit protein.
Length = 502
Score = 54.8 bits (126), Expect = 4e-07
Identities = 36/140 (25%), Positives = 67/140 (47%), Gaps = 2/140 (1%)
Frame = +1
Query: 172 DSPPDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWNVGEW-GCSTWLVSS 348
DS P + + +L+L L+ ++ E + LQM+W D L WNV E+ G T
Sbjct: 47 DSQPLT-VYFSLSL-LQIMDVDEKNQVLTTNIWLQMSWTDHYLQWNVSEYPGVKTVRFPD 104
Query: 349 ERLWRPDVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTC 525
++W+PD++L N+A + V+++G ++ + + + +P D+Q C
Sbjct: 105 GQIWKPDILLYNSADERFDATFHTNVLVNSSGHCQYLPPGIFKSSCYIDVRWFPFDVQHC 164
Query: 526 TFKFGSRMHNSDEMDFVIDQ 585
KFGS + +D + +
Sbjct: 165 KLKFGSWSYGGWSLDLQMQE 184
>U62436-1|AAB40114.1| 502|Homo sapiens nicotinic acetylcholine
receptor alpha7 subunit precursor protein.
Length = 502
Score = 54.8 bits (126), Expect = 4e-07
Identities = 36/140 (25%), Positives = 67/140 (47%), Gaps = 2/140 (1%)
Frame = +1
Query: 172 DSPPDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWNVGEW-GCSTWLVSS 348
DS P + + +L+L L+ ++ E + LQM+W D L WNV E+ G T
Sbjct: 47 DSQPLT-VYFSLSL-LQIMDVDEKNQVLTTNIWLQMSWTDHYLQWNVSEYPGVKTVRFPD 104
Query: 349 ERLWRPDVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTC 525
++W+PD++L N+A + V+++G ++ + + + +P D+Q C
Sbjct: 105 GQIWKPDILLYNSADERFDATFHTNVLVNSSGHCQYLPPGIFKSSCYIDVRWFPFDVQHC 164
Query: 526 TFKFGSRMHNSDEMDFVIDQ 585
KFGS + +D + +
Sbjct: 165 KLKFGSWSYGGWSLDLQMQE 184
>AJ586911-1|CAE52911.1| 502|Homo sapiens nicotinic acetylcholine
alpha-7 subunit protein.
Length = 502
Score = 54.8 bits (126), Expect = 4e-07
Identities = 36/140 (25%), Positives = 67/140 (47%), Gaps = 2/140 (1%)
Frame = +1
Query: 172 DSPPDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWNVGEW-GCSTWLVSS 348
DS P + + +L+L L+ ++ E + LQM+W D L WNV E+ G T
Sbjct: 47 DSQPLT-VYFSLSL-LQIMDVDEKNQVLTTNIWLQMSWTDHYLQWNVSEYPGVKTVRFPD 104
Query: 349 ERLWRPDVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTC 525
++W+PD++L N+A + V+++G ++ + + + +P D+Q C
Sbjct: 105 GQIWKPDILLYNSADERFDATFHTNVLVNSSGHCQYLPPGIFKSSCYIDVRWFPFDVQHC 164
Query: 526 TFKFGSRMHNSDEMDFVIDQ 585
KFGS + +D + +
Sbjct: 165 KLKFGSWSYGGWSLDLQMQE 184
>BC111802-1|AAI11803.1| 465|Homo sapiens CHRNG protein protein.
Length = 465
Score = 54.4 bits (125), Expect = 5e-07
Identities = 37/135 (27%), Positives = 61/135 (45%), Gaps = 7/135 (5%)
Frame = +1
Query: 73 PFLLTCAIASAAECENATSLSLMIDSLLATYDRDSPPDSKI--VVNLTLHLRHANI---R 237
P LL +A + ++ L+ YD + P + VVN++L L N+
Sbjct: 7 PLLLLLLLAVCLGAQGRNQEERLLADLMQNYDPNLRPAERDSDVVNVSLKLTLTNLISLN 66
Query: 238 ESESTVRIQADLQMNWIDKRLSWNVGEW-GCSTWLVSSERLWRPDVVLLNAAAT-TAGDY 411
E E + ++M W D RL W+ ++ G V S +WRPD+VL N + T + +
Sbjct: 67 EREEALTTNVWIEMQWCDYRLRWDPRDYEGLWVLRVPSTMVWRPDIVLENKSQTYSTNEI 126
Query: 412 ALRARVSNNGSVSWI 456
L+ + S+ WI
Sbjct: 127 DLQLSQEDGQSIEWI 141
>BC110597-1|AAI10598.1| 411|Homo sapiens ligand-gated ion channel,
zinc activated 1 protein.
Length = 411
Score = 54.4 bits (125), Expect = 5e-07
Identities = 28/101 (27%), Positives = 49/101 (48%)
Frame = +1
Query: 271 LQMNWIDKRLSWNVGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVS 450
L+++W+D RL+WN + E LW P + +L A D + +ARV +G V
Sbjct: 86 LRLSWLDTRLAWNTSAHPRHAITLPWESLWTPRLTILEALWVDWRDQSPQARVDQDGHVK 145
Query: 451 WIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDF 573
L T + +L ++P D C+ F + + + E++F
Sbjct: 146 LNLALTTETNCNFELLHFPRDHSNCSLSFYALSNTAMELEF 186
>AF512521-1|AAO20969.1| 411|Homo sapiens ligand-gated ion channel
subunit protein.
Length = 411
Score = 54.4 bits (125), Expect = 5e-07
Identities = 28/101 (27%), Positives = 49/101 (48%)
Frame = +1
Query: 271 LQMNWIDKRLSWNVGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVS 450
L+++W+D RL+WN + E LW P + +L A D + +ARV +G V
Sbjct: 86 LRLSWLDTRLAWNTSAHPRHAITLPWESLWTPRLTILEALWVDWRDQSPQARVDQDGHVK 145
Query: 451 WIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDF 573
L T + +L ++P D C+ F + + + E++F
Sbjct: 146 LNLALTTETNCNFELLHFPRDHSNCSLSFYALSNTAMELEF 186
>AB223030-1|BAE19924.1| 411|Homo sapiens ligand-gated ion-channel
receptor L2 protein.
Length = 411
Score = 54.0 bits (124), Expect = 7e-07
Identities = 28/101 (27%), Positives = 49/101 (48%)
Frame = +1
Query: 271 LQMNWIDKRLSWNVGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVS 450
L+++W+D RL+WN + E LW P + +L A D + +ARV +G V
Sbjct: 86 LRLSWLDTRLAWNTSAHPRHAITLPWESLWTPRLTILEALWVDWRDQSPQARVDQDGHVK 145
Query: 451 WIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDF 573
L T + +L ++P D C+ F + + + E++F
Sbjct: 146 LNLALATETNCNFELLHFPRDHSNCSLSFYALSNTAMELEF 186
>L08485-1|AAA58490.1| 462|Homo sapiens GABA-benzodiazepine receptor
alpha-5-subunit protein.
Length = 462
Score = 53.6 bits (123), Expect = 9e-07
Identities = 39/161 (24%), Positives = 73/161 (45%), Gaps = 7/161 (4%)
Frame = +1
Query: 115 ENATSLSLMIDSLLATYDRDSPPD--SKIV-VNLTLHLRHAN-IRESESTVRIQADLQMN 282
+N T + ++D LL YD P +I V +++ + ++E I + +
Sbjct: 44 DNITIFTRILDGLLDGYDNRLRPGLGERITQVRTDIYVTSFGPVSDTEMEYTIDVFFRQS 103
Query: 283 WIDKRLSWNVGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSW 453
W D+RL + + + ++W PD N + A + R+ ++G++ +
Sbjct: 104 WKDERLRFKGPMQRLPLNNLLASKIWTPDTFFHNGKKSIAHNMTTPNKLLRLEDDGTLLY 163
Query: 454 IKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFV 576
RL IS MQL+++P D C KFGS + + E+ +V
Sbjct: 164 TMRLTISAECPMQLEDFPMDAHACPLKFGSYAYPNSEVVYV 204
>BT009830-1|AAP88832.1| 462|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 5 protein.
Length = 462
Score = 53.6 bits (123), Expect = 9e-07
Identities = 39/161 (24%), Positives = 73/161 (45%), Gaps = 7/161 (4%)
Frame = +1
Query: 115 ENATSLSLMIDSLLATYDRDSPPD--SKIV-VNLTLHLRHAN-IRESESTVRIQADLQMN 282
+N T + ++D LL YD P +I V +++ + ++E I + +
Sbjct: 44 DNITIFTRILDGLLDGYDNRLRPGLGERITQVRTDIYVTSFGPVSDTEMEYTIDVFFRQS 103
Query: 283 WIDKRLSWNVGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSW 453
W D+RL + + + ++W PD N + A + R+ ++G++ +
Sbjct: 104 WKDERLRFKGPMQRLPLNNLLASKIWTPDTFFHNGKKSIAHNMTTPNKLLRLEDDGTLLY 163
Query: 454 IKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFV 576
RL IS MQL+++P D C KFGS + + E+ +V
Sbjct: 164 TMRLTISAECPMQLEDFPMDAHACPLKFGSYAYPNSEVVYV 204
>BC113422-1|AAI13423.1| 462|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 5 protein.
Length = 462
Score = 53.6 bits (123), Expect = 9e-07
Identities = 39/161 (24%), Positives = 73/161 (45%), Gaps = 7/161 (4%)
Frame = +1
Query: 115 ENATSLSLMIDSLLATYDRDSPPD--SKIV-VNLTLHLRHAN-IRESESTVRIQADLQMN 282
+N T + ++D LL YD P +I V +++ + ++E I + +
Sbjct: 44 DNITIFTRILDGLLDGYDNRLRPGLGERITQVRTDIYVTSFGPVSDTEMEYTIDVFFRQS 103
Query: 283 WIDKRLSWNVGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSW 453
W D+RL + + + ++W PD N + A + R+ ++G++ +
Sbjct: 104 WKDERLRFKGPMQRLPLNNLLASKIWTPDTFFHNGKKSIAHNMTTPNKLLRLEDDGTLLY 163
Query: 454 IKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFV 576
RL IS MQL+++P D C KFGS + + E+ +V
Sbjct: 164 TMRLTISAECPMQLEDFPMDAHACPLKFGSYAYPNSEVVYV 204
>BC111979-1|AAI11980.1| 462|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 5, precursor protein.
Length = 462
Score = 53.6 bits (123), Expect = 9e-07
Identities = 39/161 (24%), Positives = 73/161 (45%), Gaps = 7/161 (4%)
Frame = +1
Query: 115 ENATSLSLMIDSLLATYDRDSPPD--SKIV-VNLTLHLRHAN-IRESESTVRIQADLQMN 282
+N T + ++D LL YD P +I V +++ + ++E I + +
Sbjct: 44 DNITIFTRILDGLLDGYDNRLRPGLGERITQVRTDIYVTSFGPVSDTEMEYTIDVFFRQS 103
Query: 283 WIDKRLSWNVGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSW 453
W D+RL + + + ++W PD N + A + R+ ++G++ +
Sbjct: 104 WKDERLRFKGPMQRLPLNNLLASKIWTPDTFFHNGKKSIAHNMTTPNKLLRLEDDGTLLY 163
Query: 454 IKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFV 576
RL IS MQL+++P D C KFGS + + E+ +V
Sbjct: 164 TMRLTISAECPMQLEDFPMDAHACPLKFGSYAYPNSEVVYV 204
>U40583-1|AAA83561.1| 502|Homo sapiens alpha 7 neuronal nicotinic
acetylcholine receptor protein.
Length = 502
Score = 53.2 bits (122), Expect = 1e-06
Identities = 36/140 (25%), Positives = 65/140 (46%), Gaps = 2/140 (1%)
Frame = +1
Query: 172 DSPPDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWNVGEW-GCSTWLVSS 348
DS P + + +L L L+ ++ E + LQM+W D L WNV E+ G T
Sbjct: 47 DSQPLT-VYFSLNL-LQIMDVDEKNQVLTTNIWLQMSWTDHYLQWNVSEYPGVKTVRFPD 104
Query: 349 ERLWRPDVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTC 525
++W+PD++L N+A + V+ +G ++ + + + +P D+Q C
Sbjct: 105 GQIWKPDILLYNSADERFDATFHTNVLVNPSGHCQYLPPGIFKSSCYIDVRWFPFDVQHC 164
Query: 526 TFKFGSRMHNSDEMDFVIDQ 585
KFGS + +D + +
Sbjct: 165 KLKFGSWSYGGWSLDLQMQE 184
>AF385585-1|AAK68111.1| 502|Homo sapiens nicotinic cholinergic
receptor alpha 7 protein.
Length = 502
Score = 53.2 bits (122), Expect = 1e-06
Identities = 36/140 (25%), Positives = 65/140 (46%), Gaps = 2/140 (1%)
Frame = +1
Query: 172 DSPPDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWNVGEW-GCSTWLVSS 348
DS P + + +L L L+ ++ E + LQM+W D L WNV E+ G T
Sbjct: 47 DSQPLT-VYFSLNL-LQIMDVDEKNQVLTTNIWLQMSWTDHYLQWNVSEYPGVKTVRFPD 104
Query: 349 ERLWRPDVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTC 525
++W+PD++L N+A + V+ +G ++ + + + +P D+Q C
Sbjct: 105 GQIWKPDILLYNSADERFDATFHTNVLVNPSGHCQYLPPGIFKSSCYIDVRWFPFDVQHC 164
Query: 526 TFKFGSRMHNSDEMDFVIDQ 585
KFGS + +D + +
Sbjct: 165 KLKFGSWSYGGWSLDLQMQE 184
>S82612-1|AAB37533.2| 478|Homo sapiens 5-hydroxytryptamine type 3AS
receptor subunit protein.
Length = 478
Score = 52.4 bits (120), Expect = 2e-06
Identities = 39/175 (22%), Positives = 74/175 (42%), Gaps = 6/175 (3%)
Frame = +1
Query: 64 ILLPFLLTCAIASAAECENATSLSLMIDSLLATYDRDSPP--DSKIVVNLTLHL---RHA 228
+LLP LL A + +L + D LL Y + P D + +++ +
Sbjct: 12 LLLPTLLAQGEARRSRNTTRPALLRLSDYLLTNYTKGVRPVRDWRKPTTVSIDVIVYAIL 71
Query: 229 NIRESESTVRIQADLQMNWIDKRLSWNVGEWGCSTWL-VSSERLWRPDVVLLNAAATTAG 405
N+ E + + W D+ L WN ++ T L + ++ +W PD+++
Sbjct: 72 NVDEKNQVLTTYIWYRQYWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINELVDVGKS 131
Query: 406 DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 570
+ + G V K L + T S+ + N+P D+Q C+ F S +H +++
Sbjct: 132 PNIPYVYIRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLHTIQDIN 186
>M59216-1|AAA35862.1| 474|Homo sapiens gamma-aminobutyric acid
receptor beta-1 subunit protein.
Length = 474
Score = 52.4 bits (120), Expect = 2e-06
Identities = 42/180 (23%), Positives = 79/180 (43%), Gaps = 9/180 (5%)
Frame = +1
Query: 61 IILLPFLLT--CAIASAAECENATSLSLMIDSLLATYDRDSPPD---SKIVVNLTLHLRH 225
++ P ++T C S E N + + +D LL YD PD + V + + +
Sbjct: 12 LLSFPVMITMVCCAHSTNEPSNMSYVKETVDRLLKGYDIRLRPDFGGPPVDVGMRIDVAS 71
Query: 226 AN-IRESESTVRIQADLQMNWIDKRLSWNVGEWGCSTWLVSSERLWRPDVVLLNAAATTA 402
+ + E + Q +W DKRLS++ + +++LW PD LN +
Sbjct: 72 IDMVSEVNMDYTLTMYFQQSWKDKRLSYSGIPLNLTLDNRVADQLWVPDTYFLNDKKSFV 131
Query: 403 GDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDF 573
++ R+ +G+V + R+ + M L +P D Q CT + S + +D+++F
Sbjct: 132 HGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEF 191
>AJ003080-1|CAA05853.1| 238|Homo sapiens serotonin receptor
protein.
Length = 238
Score = 52.4 bits (120), Expect = 2e-06
Identities = 40/171 (23%), Positives = 72/171 (42%), Gaps = 6/171 (3%)
Frame = +1
Query: 64 ILLPFLLTCAIASAAECENATSLSLMIDSLLATYDRDSPP--DSKIVVNLTLHL---RHA 228
+LLP LL A + +L + D LL Y + P D + +++ +
Sbjct: 12 LLLPTLLAQGEARRSRNTTRPALLRLSDYLLTNYRKGVRPVRDWRKPTTVSIDVIVYAIL 71
Query: 229 NIRESESTVRIQADLQMNWIDKRLSWNVGEWGCSTWL-VSSERLWRPDVVLLNAAATTAG 405
N+ E + + W D+ L WN ++ T L + ++ +W PD+++
Sbjct: 72 NVDEKNQVLTTYIWYRQYWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKS 131
Query: 406 DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNS 558
+ + G V K L + T S+ + N+P D+Q C+ F S +H S
Sbjct: 132 PNIPYVYIRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLHTS 182
>X14767-1|CAA32875.1| 474|Homo sapiens GABA-A receptor beta 1
subunit protein.
Length = 474
Score = 51.6 bits (118), Expect = 4e-06
Identities = 42/180 (23%), Positives = 78/180 (43%), Gaps = 9/180 (5%)
Frame = +1
Query: 61 IILLPFLLT--CAIASAAECENATSLSLMIDSLLATYDRDSPPD---SKIVVNLTLHLRH 225
++ P ++T C S E N + +D LL YD PD + V + + +
Sbjct: 12 LLSFPVMITMVCCAHSTNEPSNMPYVKETVDRLLKGYDIRLRPDFGGPPVDVGMRIDVAS 71
Query: 226 AN-IRESESTVRIQADLQMNWIDKRLSWNVGEWGCSTWLVSSERLWRPDVVLLNAAATTA 402
+ + E + Q +W DKRLS++ + +++LW PD LN +
Sbjct: 72 IDMVSEVNMDYTLTMYFQQSWKDKRLSYSGIPLNLTLDNRVADQLWVPDTYFLNDKKSFV 131
Query: 403 GDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDF 573
++ R+ +G+V + R+ + M L +P D Q CT + S + +D+++F
Sbjct: 132 HGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEF 191
>D49394-1|BAA08387.1| 478|Homo sapiens serotonin 5-HT3 receptor
protein.
Length = 478
Score = 51.6 bits (118), Expect = 4e-06
Identities = 39/175 (22%), Positives = 74/175 (42%), Gaps = 6/175 (3%)
Frame = +1
Query: 64 ILLPFLLTCAIASAAECENATSLSLMIDSLLATYDRDSPP--DSKIVVNLTLHL---RHA 228
+LLP LL A + +L + D LL Y + P D + +++ +
Sbjct: 12 LLLPTLLAQGEARRSRNTTRPALLRLSDYLLTNYRKGVRPVRDWRKPTTVSIDVIVYAIL 71
Query: 229 NIRESESTVRIQADLQMNWIDKRLSWNVGEWGCSTWL-VSSERLWRPDVVLLNAAATTAG 405
N+ E + + W D+ L WN ++ T L + ++ +W PD+++
Sbjct: 72 NVDEKNQVLTTYIWYRQYWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKS 131
Query: 406 DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 570
+ + G V K L + T S+ + N+P D+Q C+ F S +H +++
Sbjct: 132 PNIPYVYIRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLHTIQDIN 186
>BT007204-1|AAP35868.1| 484|Homo sapiens 5-hydroxytryptamine
(serotonin) receptor 3A protein.
Length = 484
Score = 51.6 bits (118), Expect = 4e-06
Identities = 39/175 (22%), Positives = 74/175 (42%), Gaps = 6/175 (3%)
Frame = +1
Query: 64 ILLPFLLTCAIASAAECENATSLSLMIDSLLATYDRDSPP--DSKIVVNLTLHL---RHA 228
+LLP LL A + +L + D LL Y + P D + +++ +
Sbjct: 18 LLLPTLLAQGEARRSRNTTRPALLRLSDYLLTNYRKGVRPVRDWRKPTTVSIDVIVYAIL 77
Query: 229 NIRESESTVRIQADLQMNWIDKRLSWNVGEWGCSTWL-VSSERLWRPDVVLLNAAATTAG 405
N+ E + + W D+ L WN ++ T L + ++ +W PD+++
Sbjct: 78 NVDEKNQVLTTYIWYRQYWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKS 137
Query: 406 DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 570
+ + G V K L + T S+ + N+P D+Q C+ F S +H +++
Sbjct: 138 PNIPYVYIRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLHTIQDIN 192
>BC004453-1|AAH04453.2| 478|Homo sapiens 5-hydroxytryptamine
(serotonin) receptor 3A protein.
Length = 478
Score = 51.6 bits (118), Expect = 4e-06
Identities = 39/175 (22%), Positives = 74/175 (42%), Gaps = 6/175 (3%)
Frame = +1
Query: 64 ILLPFLLTCAIASAAECENATSLSLMIDSLLATYDRDSPP--DSKIVVNLTLHL---RHA 228
+LLP LL A + +L + D LL Y + P D + +++ +
Sbjct: 12 LLLPTLLAQGEARRSRNTTRPALLRLSDYLLTNYRKGVRPVRDWRKPTTVSIDVIVYAIL 71
Query: 229 NIRESESTVRIQADLQMNWIDKRLSWNVGEWGCSTWL-VSSERLWRPDVVLLNAAATTAG 405
N+ E + + W D+ L WN ++ T L + ++ +W PD+++
Sbjct: 72 NVDEKNQVLTTYIWYRQYWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKS 131
Query: 406 DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 570
+ + G V K L + T S+ + N+P D+Q C+ F S +H +++
Sbjct: 132 PNIPYVYIRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLHTIQDIN 186
>BC002354-1|AAH02354.1| 478|Homo sapiens 5-hydroxytryptamine
(serotonin) receptor 3A protein.
Length = 478
Score = 51.6 bits (118), Expect = 4e-06
Identities = 39/175 (22%), Positives = 74/175 (42%), Gaps = 6/175 (3%)
Frame = +1
Query: 64 ILLPFLLTCAIASAAECENATSLSLMIDSLLATYDRDSPP--DSKIVVNLTLHL---RHA 228
+LLP LL A + +L + D LL Y + P D + +++ +
Sbjct: 12 LLLPTLLAQGEARRSRNTTRPALLRLSDYLLTNYRKGVRPVRDWRKPTTVSIDVIVYAIL 71
Query: 229 NIRESESTVRIQADLQMNWIDKRLSWNVGEWGCSTWL-VSSERLWRPDVVLLNAAATTAG 405
N+ E + + W D+ L WN ++ T L + ++ +W PD+++
Sbjct: 72 NVDEKNQVLTTYIWYRQYWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKS 131
Query: 406 DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 570
+ + G V K L + T S+ + N+P D+Q C+ F S +H +++
Sbjct: 132 PNIPYVYIRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLHTIQDIN 186
>AJ005205-1|CAA06442.3| 478|Homo sapiens serotonin 3 receptor
protein.
Length = 478
Score = 51.6 bits (118), Expect = 4e-06
Identities = 39/175 (22%), Positives = 74/175 (42%), Gaps = 6/175 (3%)
Frame = +1
Query: 64 ILLPFLLTCAIASAAECENATSLSLMIDSLLATYDRDSPP--DSKIVVNLTLHL---RHA 228
+LLP LL A + +L + D LL Y + P D + +++ +
Sbjct: 12 LLLPTLLAQGEARRSRNTTRPALLRLSDYLLTNYRKGVRPVRDWRKPTTVSIDVIVYAIL 71
Query: 229 NIRESESTVRIQADLQMNWIDKRLSWNVGEWGCSTWL-VSSERLWRPDVVLLNAAATTAG 405
N+ E + + W D+ L WN ++ T L + ++ +W PD+++
Sbjct: 72 NVDEKNQVLTTYIWYRQYWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKS 131
Query: 406 DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 570
+ + G V K L + T S+ + N+P D+Q C+ F S +H +++
Sbjct: 132 PNIPYVYIRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLHTIQDIN 186
>AJ003079-1|CAA05852.1| 478|Homo sapiens 5-hydroxytryptamine3
receptor protein.
Length = 478
Score = 51.6 bits (118), Expect = 4e-06
Identities = 39/175 (22%), Positives = 74/175 (42%), Gaps = 6/175 (3%)
Frame = +1
Query: 64 ILLPFLLTCAIASAAECENATSLSLMIDSLLATYDRDSPP--DSKIVVNLTLHL---RHA 228
+LLP LL A + +L + D LL Y + P D + +++ +
Sbjct: 12 LLLPTLLAQGEARRSRNTTRPALLRLSDYLLTNYRKGVRPVRDWRKPTTVSIDVIVYAIL 71
Query: 229 NIRESESTVRIQADLQMNWIDKRLSWNVGEWGCSTWL-VSSERLWRPDVVLLNAAATTAG 405
N+ E + + W D+ L WN ++ T L + ++ +W PD+++
Sbjct: 72 NVDEKNQVLTTYIWYRQYWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKS 131
Query: 406 DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 570
+ + G V K L + T S+ + N+P D+Q C+ F S +H +++
Sbjct: 132 PNIPYVYIRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLHTIQDIN 186
>AJ003078-1|CAA05851.1| 510|Homo sapiens serotonin receptor
protein.
Length = 510
Score = 51.6 bits (118), Expect = 4e-06
Identities = 39/175 (22%), Positives = 74/175 (42%), Gaps = 6/175 (3%)
Frame = +1
Query: 64 ILLPFLLTCAIASAAECENATSLSLMIDSLLATYDRDSPP--DSKIVVNLTLHL---RHA 228
+LLP LL A + +L + D LL Y + P D + +++ +
Sbjct: 12 LLLPTLLAQGEARRSRNTTRPALLRLSDYLLTNYRKGVRPVRDWRKPTTVSIDVIVYAIL 71
Query: 229 NIRESESTVRIQADLQMNWIDKRLSWNVGEWGCSTWL-VSSERLWRPDVVLLNAAATTAG 405
N+ E + + W D+ L WN ++ T L + ++ +W PD+++
Sbjct: 72 NVDEKNQVLTTYIWYRQYWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKS 131
Query: 406 DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 570
+ + G V K L + T S+ + N+P D+Q C+ F S +H +++
Sbjct: 132 PNIPYVYIRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLHTIQDIN 186
>AF498984-1|AAM21131.1| 478|Homo sapiens 5-hydroxytryptamine
receptor 3A protein.
Length = 478
Score = 51.6 bits (118), Expect = 4e-06
Identities = 39/175 (22%), Positives = 74/175 (42%), Gaps = 6/175 (3%)
Frame = +1
Query: 64 ILLPFLLTCAIASAAECENATSLSLMIDSLLATYDRDSPP--DSKIVVNLTLHL---RHA 228
+LLP LL A + +L + D LL Y + P D + +++ +
Sbjct: 12 LLLPTLLAQGEARRSRNTTRPALLRLSDYLLTNYRKGVRPVRDWRKPTTVSIDVIVYAIL 71
Query: 229 NIRESESTVRIQADLQMNWIDKRLSWNVGEWGCSTWL-VSSERLWRPDVVLLNAAATTAG 405
N+ E + + W D+ L WN ++ T L + ++ +W PD+++
Sbjct: 72 NVDEKNQVLTTYIWYRQYWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKS 131
Query: 406 DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 570
+ + G V K L + T S+ + N+P D+Q C+ F S +H +++
Sbjct: 132 PNIPYVYIRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLHTIQDIN 186
>BC028629-1|AAH28629.1| 492|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 3 protein.
Length = 492
Score = 50.8 bits (116), Expect = 7e-06
Identities = 36/158 (22%), Positives = 70/158 (44%), Gaps = 7/158 (4%)
Frame = +1
Query: 115 ENATSLSLMIDSLLATYDRDSPP---DSKIVVNLTLHLRHAN-IRESESTVRIQADLQMN 282
+N T + ++D LL YD P D+ V +++ + +++ I +
Sbjct: 62 DNITIFTRILDRLLDGYDNRLRPGLGDAVTEVKTDIYVTSFGPVSDTDMEYTIDVFFRQT 121
Query: 283 WIDKRLSWNVGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSW 453
W D+RL ++ + + ++W PD N + A + R+ +NG++ +
Sbjct: 122 WHDERLKFDGPMKILPLNNLLASKIWTPDTFFHNGKKSVAHNMTTPNKLLRLVDNGTLPY 181
Query: 454 IKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEM 567
RL I M L+++P D+ C KFGS + + E+
Sbjct: 182 TMRLTIHAECPMHLEDFPMDVHACPLKFGSYAYTTAEV 219
>AK122638-1|BAC85499.1| 266|Homo sapiens yte protein of 76kDa)
(LCP2). protein.
Length = 266
Score = 50.8 bits (116), Expect = 7e-06
Identities = 26/89 (29%), Positives = 42/89 (47%)
Frame = +1
Query: 271 LQMNWIDKRLSWNVGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVS 450
L+++W+D RL+WN + E LW P + +L A D + +ARV +G V
Sbjct: 87 LRLSWLDTRLAWNTSAHPRHAITLPWESLWTPRLTILEALWVDWRDQSPQARVDQDGHVK 146
Query: 451 WIKRLDISTPISMQLDNWPNDMQTCTFKF 537
L T + +L ++P D C+ F
Sbjct: 147 LNLALTTETNCNFELLHFPRDHSNCSLSF 175
>U77731-2|AAB38273.1| 360|Homo sapiens glycine receptor alpha 2B
subunit protein.
Length = 360
Score = 50.4 bits (115), Expect = 9e-06
Identities = 33/135 (24%), Positives = 60/135 (44%), Gaps = 4/135 (2%)
Frame = +1
Query: 181 PDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWN-VGEWGCSTWLVSSERL 357
P + N+ ++ +I E+ R+ L+ W D RL+++ + + +
Sbjct: 69 PPVNVTCNIFIN-SFGSIAETTMDYRVNIFLRQQWNDSRLAYSEYPDDSLDLDPSMLDSI 127
Query: 358 WRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCT 528
W+PD+ N D R+S NG V + RL ++ M L N+P D+QTCT
Sbjct: 128 WKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNFPMDVQTCT 187
Query: 529 FKFGSRMHNSDEMDF 573
+ S + +++ F
Sbjct: 188 MQLESFGYTMNDLIF 202
>S62908-1|AAB27279.1| 492|Homo sapiens gamma-aminobutyric acidA
receptor alpha 3 subunit protein.
Length = 492
Score = 50.4 bits (115), Expect = 9e-06
Identities = 36/158 (22%), Positives = 70/158 (44%), Gaps = 7/158 (4%)
Frame = +1
Query: 115 ENATSLSLMIDSLLATYDRDSPP---DSKIVVNLTLHLRHAN-IRESESTVRIQADLQMN 282
+N T + ++D LL YD P D+ V +++ + +++ I +
Sbjct: 62 DNITIFTRILDRLLDGYDNRLRPGLGDAVTEVKTDIYVTSFGPVSDTDMEYTIDVFFRQT 121
Query: 283 WIDKRLSWNVGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSW 453
W D+RL ++ + + ++W PD N + A + R+ +NG++ +
Sbjct: 122 WHDERLKFDGPMKILPLNNLLASKIWTPDTFFHNGKKSVAHNMTTPNKLLRLVDNGTLLY 181
Query: 454 IKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEM 567
RL I M L+++P D+ C KFGS + + E+
Sbjct: 182 TMRLTIHAECPMHLEDFPMDVHACPLKFGSYAYTTAEV 219
>CR450343-1|CAG29339.1| 452|Homo sapiens GLRA2 protein.
Length = 452
Score = 50.4 bits (115), Expect = 9e-06
Identities = 33/135 (24%), Positives = 60/135 (44%), Gaps = 4/135 (2%)
Frame = +1
Query: 181 PDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWN-VGEWGCSTWLVSSERL 357
P + N+ ++ +I E+ R+ L+ W D RL+++ + + +
Sbjct: 69 PPVNVTCNIFIN-SFGSIAETTMDYRVNIFLRQQWNDSRLAYSEYPDDSLDLDPSMLDSI 127
Query: 358 WRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCT 528
W+PD+ N D R+S NG V + RL ++ M L N+P D+QTCT
Sbjct: 128 WKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNFPMDVQTCT 187
Query: 529 FKFGSRMHNSDEMDF 573
+ S + +++ F
Sbjct: 188 MQLESFGYTMNDLIF 202
>AY437084-1|AAR87843.1| 452|Homo sapiens glycine receptor alpha2
subunit B protein.
Length = 452
Score = 50.4 bits (115), Expect = 9e-06
Identities = 33/135 (24%), Positives = 60/135 (44%), Gaps = 4/135 (2%)
Frame = +1
Query: 181 PDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWN-VGEWGCSTWLVSSERL 357
P + N+ ++ +I E+ R+ L+ W D RL+++ + + +
Sbjct: 69 PPVNVTCNIFIN-SFGSIAETTMDYRVNIFLRQQWNDSRLAYSEYPDDSLDLDPSMLDSI 127
Query: 358 WRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCT 528
W+PD+ N D R+S NG V + RL ++ M L N+P D+QTCT
Sbjct: 128 WKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNFPMDVQTCT 187
Query: 529 FKFGSRMHNSDEMDF 573
+ S + +++ F
Sbjct: 188 MQLESFGYTMNDLIF 202
>AF166361-1|AAG12455.1| 492|Homo sapiens GABA receptor subunit
alpha 3 protein.
Length = 492
Score = 50.4 bits (115), Expect = 9e-06
Identities = 36/158 (22%), Positives = 70/158 (44%), Gaps = 7/158 (4%)
Frame = +1
Query: 115 ENATSLSLMIDSLLATYDRDSPP---DSKIVVNLTLHLRHAN-IRESESTVRIQADLQMN 282
+N T + ++D LL YD P D+ V +++ + +++ I +
Sbjct: 62 DNITIFTRILDRLLDGYDNRLRPGLGDAVTEVKTDIYVTSFGPVSDTDMEYTIDVFFRQT 121
Query: 283 WIDKRLSWNVGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSW 453
W D+RL ++ + + ++W PD N + A + R+ +NG++ +
Sbjct: 122 WHDERLKFDGPMKILPLNNLLASKIWTPDTFFHNGKKSVAHNMTTPNKLLRLVDNGTLLY 181
Query: 454 IKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEM 567
RL I M L+++P D+ C KFGS + + E+
Sbjct: 182 TMRLTIHAECPMHLEDFPMDVHACPLKFGSYAYTTAEV 219
>X52008-1|CAA36257.1| 452|Homo sapiens inhibitory glycine receptor
protein.
Length = 452
Score = 50.0 bits (114), Expect = 1e-05
Identities = 32/135 (23%), Positives = 60/135 (44%), Gaps = 4/135 (2%)
Frame = +1
Query: 181 PDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWN-VGEWGCSTWLVSSERL 357
P + N+ ++ ++ E+ R+ L+ W D RL+++ + + +
Sbjct: 69 PPVNVTCNIFIN-SFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPDDSLDLDPSMLDSI 127
Query: 358 WRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCT 528
W+PD+ N D R+S NG V + RL ++ M L N+P D+QTCT
Sbjct: 128 WKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNFPMDVQTCT 187
Query: 529 FKFGSRMHNSDEMDF 573
+ S + +++ F
Sbjct: 188 MQLESFGYTMNDLIF 202
>U77731-1|AAB38272.1| 360|Homo sapiens glycine receptor alpha 2
subunit protein.
Length = 360
Score = 50.0 bits (114), Expect = 1e-05
Identities = 32/135 (23%), Positives = 60/135 (44%), Gaps = 4/135 (2%)
Frame = +1
Query: 181 PDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWN-VGEWGCSTWLVSSERL 357
P + N+ ++ ++ E+ R+ L+ W D RL+++ + + +
Sbjct: 69 PPVNVTCNIFIN-SFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPDDSLDLDPSMLDSI 127
Query: 358 WRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCT 528
W+PD+ N D R+S NG V + RL ++ M L N+P D+QTCT
Sbjct: 128 WKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNFPMDVQTCT 187
Query: 529 FKFGSRMHNSDEMDF 573
+ S + +++ F
Sbjct: 188 MQLESFGYTMNDLIF 202
>BC032864-1|AAH32864.1| 452|Homo sapiens glycine receptor, alpha 2
protein.
Length = 452
Score = 50.0 bits (114), Expect = 1e-05
Identities = 32/135 (23%), Positives = 60/135 (44%), Gaps = 4/135 (2%)
Frame = +1
Query: 181 PDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWN-VGEWGCSTWLVSSERL 357
P + N+ ++ ++ E+ R+ L+ W D RL+++ + + +
Sbjct: 69 PPVNVTCNIFIN-SFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPDDSLDLDPSMLDSI 127
Query: 358 WRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCT 528
W+PD+ N D R+S NG V + RL ++ M L N+P D+QTCT
Sbjct: 128 WKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNFPMDVQTCT 187
Query: 529 FKFGSRMHNSDEMDF 573
+ S + +++ F
Sbjct: 188 MQLESFGYTMNDLIF 202
>AY437083-1|AAR87842.1| 452|Homo sapiens glycine receptor alpha2
subunit A protein.
Length = 452
Score = 50.0 bits (114), Expect = 1e-05
Identities = 32/135 (23%), Positives = 60/135 (44%), Gaps = 4/135 (2%)
Frame = +1
Query: 181 PDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWN-VGEWGCSTWLVSSERL 357
P + N+ ++ ++ E+ R+ L+ W D RL+++ + + +
Sbjct: 69 PPVNVTCNIFIN-SFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPDDSLDLDPSMLDSI 127
Query: 358 WRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCT 528
W+PD+ N D R+S NG V + RL ++ M L N+P D+QTCT
Sbjct: 128 WKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNFPMDVQTCT 187
Query: 529 FKFGSRMHNSDEMDF 573
+ S + +++ F
Sbjct: 188 MQLESFGYTMNDLIF 202
>AF053495-1|AAC35290.1| 452|Homo sapiens glycine receptor alpha 2
subunit protein.
Length = 452
Score = 50.0 bits (114), Expect = 1e-05
Identities = 32/135 (23%), Positives = 60/135 (44%), Gaps = 4/135 (2%)
Frame = +1
Query: 181 PDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWN-VGEWGCSTWLVSSERL 357
P + N+ ++ ++ E+ R+ L+ W D RL+++ + + +
Sbjct: 69 PPVNVTCNIFIN-SFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPDDSLDLDPSMLDSI 127
Query: 358 WRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCT 528
W+PD+ N D R+S NG V + RL ++ M L N+P D+QTCT
Sbjct: 128 WKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNFPMDVQTCT 187
Query: 529 FKFGSRMHNSDEMDF 573
+ S + +++ F
Sbjct: 188 MQLESFGYTMNDLIF 202
>S82769-1|AAB39369.1| 467|Homo sapiens GABAA receptor gamma 3
subunit protein.
Length = 467
Score = 49.2 bits (112), Expect = 2e-05
Identities = 37/155 (23%), Positives = 66/155 (42%), Gaps = 7/155 (4%)
Frame = +1
Query: 124 TSLSLMIDSLLATYDRDSPPDSKI---VVNLTLHLRHAN-IRESESTVRIQADLQMNWID 291
T ++L+++ LL YD+ PD I V+++ +++ + +I W D
Sbjct: 45 TDVTLILNKLLREYDKKLRPDIGIKPTVIDVDIYVNSIGPVSSINMEYQIDIFFAQTWTD 104
Query: 292 KRLSWNVGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKR 462
RL +N + +W PD + N+ A R+ N+G + + R
Sbjct: 105 SRLRFNSTMKILTLNSNMVGLIWIPDTIFRNSKTAEAHWITTPNQLLRIWNDGKILYTLR 164
Query: 463 LDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEM 567
L I+ +QL N+P D +C F S + +EM
Sbjct: 165 LTINAECQLQLHNFPMDEHSCPLIFSSYGYPKEEM 199
>AF269144-1|AAF99698.1| 467|Homo sapiens GABAA receptor gamma 3
subunit protein.
Length = 467
Score = 49.2 bits (112), Expect = 2e-05
Identities = 37/155 (23%), Positives = 66/155 (42%), Gaps = 7/155 (4%)
Frame = +1
Query: 124 TSLSLMIDSLLATYDRDSPPDSKI---VVNLTLHLRHAN-IRESESTVRIQADLQMNWID 291
T ++L+++ LL YD+ PD I V+++ +++ + +I W D
Sbjct: 45 TDVTLILNKLLREYDKKLRPDIGIKPTVIDVDIYVNSIGPVSSINMEYQIDIFFAQTWTD 104
Query: 292 KRLSWNVGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKR 462
RL +N + +W PD + N+ A R+ N+G + + R
Sbjct: 105 SRLRFNSTMKILTLNSNMVGLIWIPDTIFRNSKTAEAHWITTPNQLLRIWNDGKILYTLR 164
Query: 463 LDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEM 567
L I+ +QL N+P D +C F S + +EM
Sbjct: 165 LTINAECQLQLHNFPMDEHSCPLIFSSYGYPKEEM 199
>AF228458-1|AAF63215.1| 449|Homo sapiens GABAA receptor gamma 3
subunit protein.
Length = 449
Score = 49.2 bits (112), Expect = 2e-05
Identities = 37/155 (23%), Positives = 66/155 (42%), Gaps = 7/155 (4%)
Frame = +1
Query: 124 TSLSLMIDSLLATYDRDSPPDSKI---VVNLTLHLRHAN-IRESESTVRIQADLQMNWID 291
T ++L+++ LL YD+ PD I V+++ +++ + +I W D
Sbjct: 27 TDVTLILNKLLREYDKKLRPDIGIKPTVIDVDIYVNSIGPVSSINMEYQIDIFFAQTWTD 86
Query: 292 KRLSWNVGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKR 462
RL +N + +W PD + N+ A R+ N+G + + R
Sbjct: 87 SRLRFNSTMKILTLNSNMVGLIWIPDTIFRNSKTAEAHWITTPNQLLRIWNDGKILYTLR 146
Query: 463 LDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEM 567
L I+ +QL N+P D +C F S + +EM
Sbjct: 147 LTINAECQLQLHNFPMDEHSCPLIFSSYGYPKEEM 181
>U30461-1|AAB52519.1| 554|Homo sapiens GABAA receptor subunit
alpha4 protein.
Length = 554
Score = 48.4 bits (110), Expect = 4e-05
Identities = 39/153 (25%), Positives = 70/153 (45%), Gaps = 10/153 (6%)
Frame = +1
Query: 139 MIDSLLATYD-RDSP----PDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLS 303
++DSLL YD R P P +++ ++ + + + E + + WIDKRL
Sbjct: 51 ILDSLLDGYDNRLRPGFGGPVTEVKTDIYV-TSFGPVSDVEMEYTMDVFFRQTWIDKRLK 109
Query: 304 WN--VGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRA---RVSNNGSVSWIKRLD 468
++ + + +V+ ++W PD N + + + R+ NG++ + RL
Sbjct: 110 YDGPIEILRLNNMMVT--KVWTPDTFFRNGKKSVSHNMTAPNKLFRIMRNGTILYTMRLT 167
Query: 469 ISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEM 567
IS M+L ++P D C KFGS + EM
Sbjct: 168 ISAECPMRLVDFPMDGHACPLKFGSYAYPKSEM 200
>BC035055-1|AAH35055.1| 554|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 4 protein.
Length = 554
Score = 48.4 bits (110), Expect = 4e-05
Identities = 39/153 (25%), Positives = 70/153 (45%), Gaps = 10/153 (6%)
Frame = +1
Query: 139 MIDSLLATYD-RDSP----PDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLS 303
++DSLL YD R P P +++ ++ + + + E + + WIDKRL
Sbjct: 51 ILDSLLDGYDNRLRPGFGGPVTEVKTDIYV-TSFGPVSDVEMEYTMDVFFRQTWIDKRLK 109
Query: 304 WN--VGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRA---RVSNNGSVSWIKRLD 468
++ + + +V+ ++W PD N + + + R+ NG++ + RL
Sbjct: 110 YDGPIEILRLNNMMVT--KVWTPDTFFRNGKKSVSHNMTAPNKLFRIMRNGTILYTMRLT 167
Query: 469 ISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEM 567
IS M+L ++P D C KFGS + EM
Sbjct: 168 ISAECPMRLVDFPMDGHACPLKFGSYAYPKSEM 200
>S81944-1|AAB36480.1| 453|Homo sapiens gamma-aminobutyric acid type
A receptor alpha 6 subunit protein.
Length = 453
Score = 48.0 bits (109), Expect = 5e-05
Identities = 36/154 (23%), Positives = 65/154 (42%), Gaps = 7/154 (4%)
Frame = +1
Query: 127 SLSLMIDSLLATYDRDSPPD---SKIVVNLTLHLRHAN-IRESESTVRIQADLQMNWIDK 294
++S ++D+LL YD P + V +++ + + E + + W D+
Sbjct: 31 NVSRILDNLLEGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTDE 90
Query: 295 RLSWNVGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRA---RVSNNGSVSWIKRL 465
RL + S + ++W PD N + A + R+ NG++ + RL
Sbjct: 91 RLKFGGPTEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTMRL 150
Query: 466 DISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEM 567
I+ M+L N+P D C KFGS + E+
Sbjct: 151 TINADCPMRLVNFPMDGHACPLKFGSYAYPKSEI 184
>BC099641-1|AAH99641.1| 453|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 6 protein.
Length = 453
Score = 48.0 bits (109), Expect = 5e-05
Identities = 36/154 (23%), Positives = 65/154 (42%), Gaps = 7/154 (4%)
Frame = +1
Query: 127 SLSLMIDSLLATYDRDSPPD---SKIVVNLTLHLRHAN-IRESESTVRIQADLQMNWIDK 294
++S ++D+LL YD P + V +++ + + E + + W D+
Sbjct: 31 NVSRILDNLLEGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTDE 90
Query: 295 RLSWNVGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRA---RVSNNGSVSWIKRL 465
RL + S + ++W PD N + A + R+ NG++ + RL
Sbjct: 91 RLKFGGPTEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTMRL 150
Query: 466 DISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEM 567
I+ M+L N+P D C KFGS + E+
Sbjct: 151 TINADCPMRLVNFPMDGHACPLKFGSYAYPKSEI 184
>BC099640-1|AAH99640.1| 453|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 6 protein.
Length = 453
Score = 48.0 bits (109), Expect = 5e-05
Identities = 36/154 (23%), Positives = 65/154 (42%), Gaps = 7/154 (4%)
Frame = +1
Query: 127 SLSLMIDSLLATYDRDSPPD---SKIVVNLTLHLRHAN-IRESESTVRIQADLQMNWIDK 294
++S ++D+LL YD P + V +++ + + E + + W D+
Sbjct: 31 NVSRILDNLLEGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTDE 90
Query: 295 RLSWNVGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRA---RVSNNGSVSWIKRL 465
RL + S + ++W PD N + A + R+ NG++ + RL
Sbjct: 91 RLKFGGPTEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTMRL 150
Query: 466 DISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEM 567
I+ M+L N+P D C KFGS + E+
Sbjct: 151 TINADCPMRLVNFPMDGHACPLKFGSYAYPKSEI 184
>BC096242-1|AAH96242.1| 453|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 6 protein.
Length = 453
Score = 48.0 bits (109), Expect = 5e-05
Identities = 36/154 (23%), Positives = 65/154 (42%), Gaps = 7/154 (4%)
Frame = +1
Query: 127 SLSLMIDSLLATYDRDSPPD---SKIVVNLTLHLRHAN-IRESESTVRIQADLQMNWIDK 294
++S ++D+LL YD P + V +++ + + E + + W D+
Sbjct: 31 NVSRILDNLLEGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTDE 90
Query: 295 RLSWNVGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRA---RVSNNGSVSWIKRL 465
RL + S + ++W PD N + A + R+ NG++ + RL
Sbjct: 91 RLKFGGPTEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTMRL 150
Query: 466 DISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEM 567
I+ M+L N+P D C KFGS + E+
Sbjct: 151 TINADCPMRLVNFPMDGHACPLKFGSYAYPKSEI 184
>BC096241-1|AAH96241.1| 453|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 6 protein.
Length = 453
Score = 48.0 bits (109), Expect = 5e-05
Identities = 36/154 (23%), Positives = 65/154 (42%), Gaps = 7/154 (4%)
Frame = +1
Query: 127 SLSLMIDSLLATYDRDSPPD---SKIVVNLTLHLRHAN-IRESESTVRIQADLQMNWIDK 294
++S ++D+LL YD P + V +++ + + E + + W D+
Sbjct: 31 NVSRILDNLLEGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTDE 90
Query: 295 RLSWNVGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRA---RVSNNGSVSWIKRL 465
RL + S + ++W PD N + A + R+ NG++ + RL
Sbjct: 91 RLKFGGPTEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTMRL 150
Query: 466 DISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEM 567
I+ M+L N+P D C KFGS + E+
Sbjct: 151 TINADCPMRLVNFPMDGHACPLKFGSYAYPKSEI 184
>BC022449-1|AAH22449.1| 474|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, beta 1 protein.
Length = 474
Score = 47.2 bits (107), Expect = 8e-05
Identities = 41/180 (22%), Positives = 78/180 (43%), Gaps = 9/180 (5%)
Frame = +1
Query: 61 IILLPFLLT--CAIASAAECENATSLSLMIDSLLATYDRDSPPD---SKIVVNLTLHLRH 225
++ P ++T C S E N + + +D LL YD PD + V + + +
Sbjct: 12 LLSFPVMITMVCCAHSTNEPSNMSYVKETVDRLLKGYDIRLRPDFGGPPVDVGMRIDVAS 71
Query: 226 AN-IRESESTVRIQADLQMNWIDKRLSWNVGEWGCSTWLVSSERLWRPDVVLLNAAATTA 402
+ + E + Q +W DKRLS++ + +++L PD LN +
Sbjct: 72 IDMVSEVNMDYTLTMYFQQSWKDKRLSYSGIPLNLTLDNRVADQLCVPDTYFLNDKKSFV 131
Query: 403 GDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDF 573
++ R+ +G+V + R+ + M L +P D Q CT + S + +D+++F
Sbjct: 132 HGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEF 191
>BC096083-1|AAH96083.1| 198|Homo sapiens CHRNB4 protein protein.
Length = 198
Score = 46.8 bits (106), Expect = 1e-04
Identities = 33/123 (26%), Positives = 58/123 (47%), Gaps = 8/123 (6%)
Frame = +1
Query: 67 LLPFLLTCAIASAAECENATSLSLMIDSLL--ATYD---RDSPPDSKIV-VNLTLHLRHA 228
L+ F L A+ C A + ++D LL Y+ R + S+++ + L L L
Sbjct: 7 LVLFFLV-ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQL 65
Query: 229 -NIRESESTVRIQADLQMNWIDKRLSWNVGEW-GCSTWLVSSERLWRPDVVLLNAAATTA 402
++ E E + L+ W D RL+WN + G + + ++R+W PD+VL N + T
Sbjct: 66 ISVNEREQIMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNKSLRTG 125
Query: 403 GDY 411
+
Sbjct: 126 STW 128
>BC096081-1|AAH96081.1| 198|Homo sapiens CHRNB4 protein protein.
Length = 198
Score = 46.8 bits (106), Expect = 1e-04
Identities = 33/123 (26%), Positives = 58/123 (47%), Gaps = 8/123 (6%)
Frame = +1
Query: 67 LLPFLLTCAIASAAECENATSLSLMIDSLL--ATYD---RDSPPDSKIV-VNLTLHLRHA 228
L+ F L A+ C A + ++D LL Y+ R + S+++ + L L L
Sbjct: 7 LVLFFLV-ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQL 65
Query: 229 -NIRESESTVRIQADLQMNWIDKRLSWNVGEW-GCSTWLVSSERLWRPDVVLLNAAATTA 402
++ E E + L+ W D RL+WN + G + + ++R+W PD+VL N + T
Sbjct: 66 ISVNEREQIMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNKSLRTG 125
Query: 403 GDY 411
+
Sbjct: 126 STW 128
>BC033801-1|AAH33801.1| 452|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, delta protein.
Length = 452
Score = 46.8 bits (106), Expect = 1e-04
Identities = 38/149 (25%), Positives = 65/149 (43%), Gaps = 7/149 (4%)
Frame = +1
Query: 142 IDSLLATYDRDSPPD-SKIVVNLTLHLRHANI---RESESTVRIQADLQMNWIDKRLSWN 309
+D L+A Y R+ P VN+ L L A+I E+ + L +W D RLS+N
Sbjct: 44 LDGLIAGYARNFRPGIGGPPVNVALALEVASIDHISEANMEYTMTVFLHQSWRDSRLSYN 103
Query: 310 VGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTP 480
++LW PD ++NA + D + R+ +G + + R+ +
Sbjct: 104 HTNETLGLDSRFVDKLWLPDTFIVNAKSAWFHDVTVENKLIRLQPDGVILYSIRITSTVA 163
Query: 481 ISMQLDNWPNDMQTCTFKFGSRMHNSDEM 567
M L +P D Q C S ++S+++
Sbjct: 164 CDMDLAKYPMDEQECMLDLESYGYSSEDI 192
>AL391845-4|CAI15436.1| 452|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, delta protein.
Length = 452
Score = 46.8 bits (106), Expect = 1e-04
Identities = 38/149 (25%), Positives = 65/149 (43%), Gaps = 7/149 (4%)
Frame = +1
Query: 142 IDSLLATYDRDSPPD-SKIVVNLTLHLRHANI---RESESTVRIQADLQMNWIDKRLSWN 309
+D L+A Y R+ P VN+ L L A+I E+ + L +W D RLS+N
Sbjct: 44 LDGLIAGYARNFRPGIGGPPVNVALALEVASIDHISEANMEYTMTVFLHQSWRDSRLSYN 103
Query: 310 VGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTP 480
++LW PD ++NA + D + R+ +G + + R+ +
Sbjct: 104 HTNETLGLDSRFVDKLWLPDTFIVNAKSAWFHDVTVENKLIRLQPDGVILYSIRITSTVA 163
Query: 481 ISMQLDNWPNDMQTCTFKFGSRMHNSDEM 567
M L +P D Q C S ++S+++
Sbjct: 164 CDMDLAKYPMDEQECMLDLESYGYSSEDI 192
>AF016917-1|AAB70007.1| 452|Homo sapiens GABA-A receptor delta
subunit protein.
Length = 452
Score = 46.8 bits (106), Expect = 1e-04
Identities = 38/149 (25%), Positives = 65/149 (43%), Gaps = 7/149 (4%)
Frame = +1
Query: 142 IDSLLATYDRDSPPD-SKIVVNLTLHLRHANI---RESESTVRIQADLQMNWIDKRLSWN 309
+D L+A Y R+ P VN+ L L A+I E+ + L +W D RLS+N
Sbjct: 44 LDGLIAGYARNFRPGIGGPPVNVALALEVASIDHISEANMEYTMTVFLHQSWRDSRLSYN 103
Query: 310 VGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTP 480
++LW PD ++NA + D + R+ +G + + R+ +
Sbjct: 104 HTNETLGLDSRFVDKLWLPDTFIVNAKSAWFHDVTVENKLIRLQPDGVILYSIRITSTVA 163
Query: 481 ISMQLDNWPNDMQTCTFKFGSRMHNSDEM 567
M L +P D Q C S ++S+++
Sbjct: 164 CDMDLAKYPMDEQECMLDLESYGYSSEDI 192
>U93917-1|AAC39917.1| 449|Homo sapiens glycine receptor alpha 3
subunit protein.
Length = 449
Score = 46.4 bits (105), Expect = 1e-04
Identities = 44/181 (24%), Positives = 77/181 (42%), Gaps = 11/181 (6%)
Frame = +1
Query: 64 ILLPFLLTCAIASAAECENATSLSLMIDSLLAT---YDRDSPPDSK-IVVNLTLHL---R 222
+LL + T SA S S +D L+ YD P+ K VN+T ++
Sbjct: 21 LLLSLVATKETDSARSRSAPMSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINS 80
Query: 223 HANIRESESTVRIQADLQMNWIDKRLSWN-VGEWGCSTWLVSSERLWRPDVVLLNAAATT 399
+I E+ R+ L+ W D RL+++ + + +W+PD+ N
Sbjct: 81 FGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGAN 140
Query: 400 AGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 570
+ R+ NG+V + RL ++ M L N+P D+QTC + S + +++
Sbjct: 141 FHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFPMDVQTCIMQLESFGYTMNDLI 200
Query: 571 F 573
F
Sbjct: 201 F 201
>BC114947-1|AAI14948.1| 457|Homo sapiens GLRA1 protein protein.
Length = 457
Score = 46.4 bits (105), Expect = 1e-04
Identities = 45/195 (23%), Positives = 86/195 (44%), Gaps = 17/195 (8%)
Frame = +1
Query: 40 HKMSTTYIILLPFLLTCAIASAAECENATSL------SLMIDSLLAT---YDRDSPPDSK 192
+ +T + L ++ ++A++ E E A S S +D L+ YD P+ K
Sbjct: 2 YSFNTLRLYLWETIVFFSLAASKEAEAARSAPKPMSPSDFLDKLMGRTSGYDARIRPNFK 61
Query: 193 -IVVNLTLHL---RHANIRESESTVRIQADLQMNWIDKRLSWN-VGEWGCSTWLVSSERL 357
VN++ ++ +I E+ R+ L+ W D RL++N + + +
Sbjct: 62 GPPVNVSCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYNEYPDDSLDLDPSMLDSI 121
Query: 358 WRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCT 528
W+PD+ N + R+S NG+V + R+ ++ M L N+P D+QTC
Sbjct: 122 WKPDLFFANEKGAHFHEITTDNKLLRISRNGNVLYSIRITLTLACPMDLKNFPMDVQTCI 181
Query: 529 FKFGSRMHNSDEMDF 573
+ S + +++ F
Sbjct: 182 MQLESFGYTMNDLIF 196
>BC074980-1|AAH74980.1| 449|Homo sapiens glycine receptor, alpha 1
(startle disease/hyperekplexia) protein.
Length = 449
Score = 46.4 bits (105), Expect = 1e-04
Identities = 45/195 (23%), Positives = 86/195 (44%), Gaps = 17/195 (8%)
Frame = +1
Query: 40 HKMSTTYIILLPFLLTCAIASAAECENATSL------SLMIDSLLAT---YDRDSPPDSK 192
+ +T + L ++ ++A++ E E A S S +D L+ YD P+ K
Sbjct: 2 YSFNTLRLYLWETIVFFSLAASKEAEAARSAPKPMSPSDFLDKLMGRTSGYDARIRPNFK 61
Query: 193 -IVVNLTLHL---RHANIRESESTVRIQADLQMNWIDKRLSWN-VGEWGCSTWLVSSERL 357
VN++ ++ +I E+ R+ L+ W D RL++N + + +
Sbjct: 62 GPPVNVSCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYNEYPDDSLDLDPSMLDSI 121
Query: 358 WRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCT 528
W+PD+ N + R+S NG+V + R+ ++ M L N+P D+QTC
Sbjct: 122 WKPDLFFANEKGAHFHEITTDNKLLRISRNGNVLYSIRITLTLACPMDLKNFPMDVQTCI 181
Query: 529 FKFGSRMHNSDEMDF 573
+ S + +++ F
Sbjct: 182 MQLESFGYTMNDLIF 196
>BC036086-1|AAH36086.1| 464|Homo sapiens glycine receptor, alpha 3
protein.
Length = 464
Score = 46.4 bits (105), Expect = 1e-04
Identities = 44/181 (24%), Positives = 77/181 (42%), Gaps = 11/181 (6%)
Frame = +1
Query: 64 ILLPFLLTCAIASAAECENATSLSLMIDSLLAT---YDRDSPPDSK-IVVNLTLHL---R 222
+LL + T SA S S +D L+ YD P+ K VN+T ++
Sbjct: 21 LLLSLVATKETDSARSRSAPMSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINS 80
Query: 223 HANIRESESTVRIQADLQMNWIDKRLSWN-VGEWGCSTWLVSSERLWRPDVVLLNAAATT 399
+I E+ R+ L+ W D RL+++ + + +W+PD+ N
Sbjct: 81 FGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGAN 140
Query: 400 AGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 570
+ R+ NG+V + RL ++ M L N+P D+QTC + S + +++
Sbjct: 141 FHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFPMDVQTCIMQLESFGYTMNDLI 200
Query: 571 F 573
F
Sbjct: 201 F 201
>AF017724-1|AAC39919.1| 465|Homo sapiens glycine receptor alpha 3
subunit protein.
Length = 465
Score = 46.4 bits (105), Expect = 1e-04
Identities = 44/181 (24%), Positives = 77/181 (42%), Gaps = 11/181 (6%)
Frame = +1
Query: 64 ILLPFLLTCAIASAAECENATSLSLMIDSLLAT---YDRDSPPDSK-IVVNLTLHL---R 222
+LL + T SA S S +D L+ YD P+ K VN+T ++
Sbjct: 21 LLLSLVATKETDSARSRSAPMSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINS 80
Query: 223 HANIRESESTVRIQADLQMNWIDKRLSWN-VGEWGCSTWLVSSERLWRPDVVLLNAAATT 399
+I E+ R+ L+ W D RL+++ + + +W+PD+ N
Sbjct: 81 FGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGAN 140
Query: 400 AGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 570
+ R+ NG+V + RL ++ M L N+P D+QTC + S + +++
Sbjct: 141 FHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFPMDVQTCIMQLESFGYTMNDLI 200
Query: 571 F 573
F
Sbjct: 201 F 201
>X52009-1|CAA36258.1| 449|Homo sapiens inhibitory glycine receptor
protein.
Length = 449
Score = 46.0 bits (104), Expect = 2e-04
Identities = 29/119 (24%), Positives = 54/119 (45%), Gaps = 4/119 (3%)
Frame = +1
Query: 229 NIRESESTVRIQADLQMNWIDKRLSWN-VGEWGCSTWLVSSERLWRPDVVLLNAAATTAG 405
+I E+ R+ L+ W D RL++N + + +W+PD+ N
Sbjct: 78 SIAETTMDYRVNIFLRQQWNDPRLAYNEYPDDSLDLDPSMLDSIWKPDLFFANEKGAHFH 137
Query: 406 DYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDF 573
+ R+S NG+V + R+ ++ M L N+P D+QTC + S + +++ F
Sbjct: 138 EITTDNKLLRISRNGNVLYSIRITLTLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIF 196
>U95367-1|AAC51357.1| 440|Homo sapiens GABA-A receptor pi subunit
protein.
Length = 440
Score = 46.0 bits (104), Expect = 2e-04
Identities = 39/163 (23%), Positives = 76/163 (46%), Gaps = 8/163 (4%)
Frame = +1
Query: 109 ECENATSLSLM-IDSLLATYDRDSPPD---SKIVVNLTLHLRH-ANIRESESTVRIQADL 273
E + LSL ++L A Y++ P+ + + LTL + ++I ES L
Sbjct: 29 EVGRSDKLSLPGFENLTAGYNKFLRPNFGGEPVQIALTLDIASISSISESNMDYTATIYL 88
Query: 274 QMNWIDKRLSWNVGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGS 444
+ W+D+RL + G + E LW PD ++ + + + + R+ +NG+
Sbjct: 89 RQRWMDQRLVFE-GNKSFTLDARLVEFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNGT 147
Query: 445 VSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDF 573
V + R+ + +M L +P D QTC + S ++ ++++F
Sbjct: 148 VLYALRITTTVACNMDLSKYPMDTQTCKLQLESWGYDGNDVEF 190
>BC109106-1|AAI09107.1| 440|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, pi protein.
Length = 440
Score = 46.0 bits (104), Expect = 2e-04
Identities = 39/163 (23%), Positives = 76/163 (46%), Gaps = 8/163 (4%)
Frame = +1
Query: 109 ECENATSLSLM-IDSLLATYDRDSPPD---SKIVVNLTLHLRH-ANIRESESTVRIQADL 273
E + LSL ++L A Y++ P+ + + LTL + ++I ES L
Sbjct: 29 EVGRSDKLSLPGFENLTAGYNKFLRPNFGGEPVQIALTLDIASISSISESNMDYTATIYL 88
Query: 274 QMNWIDKRLSWNVGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGS 444
+ W+D+RL + G + E LW PD ++ + + + + R+ +NG+
Sbjct: 89 RQRWMDQRLVFE-GNKSFTLDARLVEFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNGT 147
Query: 445 VSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDF 573
V + R+ + +M L +P D QTC + S ++ ++++F
Sbjct: 148 VLYALRITTTVACNMDLSKYPMDTQTCKLQLESWGYDGNDVEF 190
>BC109105-1|AAI09106.1| 440|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, pi protein.
Length = 440
Score = 46.0 bits (104), Expect = 2e-04
Identities = 39/163 (23%), Positives = 76/163 (46%), Gaps = 8/163 (4%)
Frame = +1
Query: 109 ECENATSLSLM-IDSLLATYDRDSPPD---SKIVVNLTLHLRH-ANIRESESTVRIQADL 273
E + LSL ++L A Y++ P+ + + LTL + ++I ES L
Sbjct: 29 EVGRSDKLSLPGFENLTAGYNKFLRPNFGGEPVQIALTLDIASISSISESNMDYTATIYL 88
Query: 274 QMNWIDKRLSWNVGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGS 444
+ W+D+RL + G + E LW PD ++ + + + + R+ +NG+
Sbjct: 89 RQRWMDQRLVFE-GNKSFTLDARLVEFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNGT 147
Query: 445 VSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDF 573
V + R+ + +M L +P D QTC + S ++ ++++F
Sbjct: 148 VLYALRITTTVACNMDLSKYPMDTQTCKLQLESWGYDGNDVEF 190
>BC074865-1|AAH74865.1| 440|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, pi protein.
Length = 440
Score = 46.0 bits (104), Expect = 2e-04
Identities = 39/163 (23%), Positives = 76/163 (46%), Gaps = 8/163 (4%)
Frame = +1
Query: 109 ECENATSLSLM-IDSLLATYDRDSPPD---SKIVVNLTLHLRH-ANIRESESTVRIQADL 273
E + LSL ++L A Y++ P+ + + LTL + ++I ES L
Sbjct: 29 EVGRSDKLSLPGFENLTAGYNKFLRPNFGGEPVQIALTLDIASISSISESNMDYTATIYL 88
Query: 274 QMNWIDKRLSWNVGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGS 444
+ W+D+RL + G + E LW PD ++ + + + + R+ +NG+
Sbjct: 89 RQRWMDQRLVFE-GNKSFTLDARLVEFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNGT 147
Query: 445 VSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDF 573
V + R+ + +M L +P D QTC + S ++ ++++F
Sbjct: 148 VLYALRITTTVACNMDLSKYPMDTQTCKLQLESWGYDGNDVEF 190
>BC074810-1|AAH74810.1| 440|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, pi protein.
Length = 440
Score = 46.0 bits (104), Expect = 2e-04
Identities = 39/163 (23%), Positives = 76/163 (46%), Gaps = 8/163 (4%)
Frame = +1
Query: 109 ECENATSLSLM-IDSLLATYDRDSPPD---SKIVVNLTLHLRH-ANIRESESTVRIQADL 273
E + LSL ++L A Y++ P+ + + LTL + ++I ES L
Sbjct: 29 EVGRSDKLSLPGFENLTAGYNKFLRPNFGGEPVQIALTLDIASISSISESNMDYTATIYL 88
Query: 274 QMNWIDKRLSWNVGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGS 444
+ W+D+RL + G + E LW PD ++ + + + + R+ +NG+
Sbjct: 89 RQRWMDQRLVFE-GNKSFTLDARLVEFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNGT 147
Query: 445 VSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDF 573
V + R+ + +M L +P D QTC + S ++ ++++F
Sbjct: 148 VLYALRITTTVACNMDLSKYPMDTQTCKLQLESWGYDGNDVEF 190
>AF009702-1|AAC24194.1| 440|Homo sapiens GABA-A receptor pi subunit
protein.
Length = 440
Score = 46.0 bits (104), Expect = 2e-04
Identities = 39/163 (23%), Positives = 76/163 (46%), Gaps = 8/163 (4%)
Frame = +1
Query: 109 ECENATSLSLM-IDSLLATYDRDSPPD---SKIVVNLTLHLRH-ANIRESESTVRIQADL 273
E + LSL ++L A Y++ P+ + + LTL + ++I ES L
Sbjct: 29 EVGRSDKLSLPGFENLTAGYNKFLRPNFGGEPVQIALTLDIASISSISESNMDYTATIYL 88
Query: 274 QMNWIDKRLSWNVGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGS 444
+ W+D+RL + G + E LW PD ++ + + + + R+ +NG+
Sbjct: 89 RQRWMDQRLVFE-GNKSFTLDARLVEFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNGT 147
Query: 445 VSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDF 573
V + R+ + +M L +P D QTC + S ++ ++++F
Sbjct: 148 VLYALRITTTVACNMDLSKYPMDTQTCKLQLESWGYDGNDVEF 190
>BC109211-1|AAI09212.1| 632|Homo sapiens gamma-aminobutyric acid
(GABA) receptor, theta protein.
Length = 632
Score = 45.6 bits (103), Expect = 2e-04
Identities = 35/145 (24%), Positives = 60/145 (41%), Gaps = 7/145 (4%)
Frame = +1
Query: 112 CENATSLSLMIDSLLATYDRDSPPD---SKIVVNLTLHLRHAN-IRESESTVRIQADLQM 279
C N + ++D +L+ YD P+ + + V +++++ I E I
Sbjct: 53 CANEAVVQKILDRVLSRYDVRLRPNFGGAPVPVRISIYVTSIEQISEMNMDYTITMFFHQ 112
Query: 280 NWIDKRLSWNVGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSN---NGSVS 450
W D RL++ + E+LW PD LN+ D + RV +G+V
Sbjct: 113 TWKDSRLAYYETTLNLTLDYRMHEKLWVPDCYFLNSKDAFVHDVTVENRVFQLHPDGTVR 172
Query: 451 WIKRLDISTPISMQLDNWPNDMQTC 525
+ RL + S+ L +P D Q C
Sbjct: 173 YGIRLTTTAACSLDLHKFPMDKQAC 197
>BC109210-1|AAI09211.1| 632|Homo sapiens gamma-aminobutyric acid
(GABA) receptor, theta protein.
Length = 632
Score = 45.6 bits (103), Expect = 2e-04
Identities = 35/145 (24%), Positives = 60/145 (41%), Gaps = 7/145 (4%)
Frame = +1
Query: 112 CENATSLSLMIDSLLATYDRDSPPD---SKIVVNLTLHLRHAN-IRESESTVRIQADLQM 279
C N + ++D +L+ YD P+ + + V +++++ I E I
Sbjct: 53 CANEAVVQKILDRVLSRYDVRLRPNFGGAPVPVRISIYVTSIEQISEMNMDYTITMFFHQ 112
Query: 280 NWIDKRLSWNVGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSN---NGSVS 450
W D RL++ + E+LW PD LN+ D + RV +G+V
Sbjct: 113 TWKDSRLAYYETTLNLTLDYRMHEKLWVPDCYFLNSKDAFVHDVTVENRVFQLHPDGTVR 172
Query: 451 WIKRLDISTPISMQLDNWPNDMQTC 525
+ RL + S+ L +P D Q C
Sbjct: 173 YGIRLTTTAACSLDLHKFPMDKQAC 197
>BC074795-1|AAH74795.1| 467|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, gamma 2 protein.
Length = 467
Score = 45.6 bits (103), Expect = 2e-04
Identities = 37/172 (21%), Positives = 76/172 (44%), Gaps = 9/172 (5%)
Frame = +1
Query: 130 LSLMIDSLLATYDRDSPPDSKIVVNLTLHLRHANIRESESTVRIQADLQM----NWIDKR 297
+++++++LL YD PD + L + N + + ++ + + W D+R
Sbjct: 66 VTVILNNLLEGYDNKLRPDIGVKPTLIHTDMYVNSIGPVNAINMEYTIDIFFAQTWYDRR 125
Query: 298 LSWN--VGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYAL---RARVSNNGSVSWIKR 462
L +N + ++ +V ++W PD N+ A R+ N+G V + R
Sbjct: 126 LKFNSTIKVLRLNSNMVG--KIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYTLR 183
Query: 463 LDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDQRIYXMFESRXW 618
L I +QL N+P D +C +F S + +E+ + + + ++R W
Sbjct: 184 LTIDAECQLQLHNFPMDEHSCPLEFSSYGYPREEIVYQWKRSSVEVGDTRSW 235
>BC069348-1|AAH69348.1| 467|Homo sapiens gamma-aminobutyric acid A
receptor, gamma 2, isoform 2 precursor protein.
Length = 467
Score = 45.6 bits (103), Expect = 2e-04
Identities = 37/172 (21%), Positives = 76/172 (44%), Gaps = 9/172 (5%)
Frame = +1
Query: 130 LSLMIDSLLATYDRDSPPDSKIVVNLTLHLRHANIRESESTVRIQADLQM----NWIDKR 297
+++++++LL YD PD + L + N + + ++ + + W D+R
Sbjct: 66 VTVILNNLLEGYDNKLRPDIGVKPTLIHTDMYVNSIGPVNAINMEYTIDIFFAQTWYDRR 125
Query: 298 LSWN--VGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYAL---RARVSNNGSVSWIKR 462
L +N + ++ +V ++W PD N+ A R+ N+G V + R
Sbjct: 126 LKFNSTIKVLRLNSNMVG--KIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYTLR 183
Query: 463 LDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDQRIYXMFESRXW 618
L I +QL N+P D +C +F S + +E+ + + + ++R W
Sbjct: 184 LTIDAECQLQLHNFPMDEHSCPLEFSSYGYPREEIVYQWKRSSVEVGDTRSW 235
>BC059389-1|AAH59389.1| 475|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, gamma 2 protein.
Length = 475
Score = 45.6 bits (103), Expect = 2e-04
Identities = 37/172 (21%), Positives = 76/172 (44%), Gaps = 9/172 (5%)
Frame = +1
Query: 130 LSLMIDSLLATYDRDSPPDSKIVVNLTLHLRHANIRESESTVRIQADLQM----NWIDKR 297
+++++++LL YD PD + L + N + + ++ + + W D+R
Sbjct: 66 VTVILNNLLEGYDNKLRPDIGVKPTLIHTDMYVNSIGPVNAINMEYTIDIFFAQTWYDRR 125
Query: 298 LSWN--VGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYAL---RARVSNNGSVSWIKR 462
L +N + ++ +V ++W PD N+ A R+ N+G V + R
Sbjct: 126 LKFNSTIKVLRLNSNMVG--KIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYTLR 183
Query: 463 LDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDQRIYXMFESRXW 618
L I +QL N+P D +C +F S + +E+ + + + ++R W
Sbjct: 184 LTIDAECQLQLHNFPMDEHSCPLEFSSYGYPREEIVYQWKRSSVEVGDTRSW 235
>AF189259-1|AAF70380.1| 632|Homo sapiens GABA-A receptor theta
subunit protein.
Length = 632
Score = 45.6 bits (103), Expect = 2e-04
Identities = 35/145 (24%), Positives = 60/145 (41%), Gaps = 7/145 (4%)
Frame = +1
Query: 112 CENATSLSLMIDSLLATYDRDSPPD---SKIVVNLTLHLRHAN-IRESESTVRIQADLQM 279
C N + ++D +L+ YD P+ + + V +++++ I E I
Sbjct: 53 CANEAVVQKILDRVLSRYDVRLRPNFGGAPVPVRISIYVTSIEQISEMNMDYTITMFFHQ 112
Query: 280 NWIDKRLSWNVGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSN---NGSVS 450
W D RL++ + E+LW PD LN+ D + RV +G+V
Sbjct: 113 TWKDSRLAYYETTLNLTLDYRMHEKLWVPDCYFLNSKDAFVHDVTVENRVFQLHPDGTVR 172
Query: 451 WIKRLDISTPISMQLDNWPNDMQTC 525
+ RL + S+ L +P D Q C
Sbjct: 173 YGIRLTTTAACSLDLHKFPMDKQAC 197
>AF165124-1|AAD50273.1| 467|Homo sapiens gamma-aminobutyric acid A
receptor gamma 2 protein.
Length = 467
Score = 45.6 bits (103), Expect = 2e-04
Identities = 37/172 (21%), Positives = 76/172 (44%), Gaps = 9/172 (5%)
Frame = +1
Query: 130 LSLMIDSLLATYDRDSPPDSKIVVNLTLHLRHANIRESESTVRIQADLQM----NWIDKR 297
+++++++LL YD PD + L + N + + ++ + + W D+R
Sbjct: 66 VTVILNNLLEGYDNKLRPDIGVKPTLIHTDMYVNSIGPVNAINMEYTIDIFFAQTWYDRR 125
Query: 298 LSWN--VGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYAL---RARVSNNGSVSWIKR 462
L +N + ++ +V ++W PD N+ A R+ N+G V + R
Sbjct: 126 LKFNSTIKVLRLNSNMVG--KIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYTLR 183
Query: 463 LDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDQRIYXMFESRXW 618
L I +QL N+P D +C +F S + +E+ + + + ++R W
Sbjct: 184 LTIDAECQLQLHNFPMDEHSCPLEFSSYGYPREEIVYQWKRSSVEVGDTRSW 235
>AF144648-1|AAD51172.1| 627|Homo sapiens GABA-A receptor theta
protein.
Length = 627
Score = 45.6 bits (103), Expect = 2e-04
Identities = 35/145 (24%), Positives = 60/145 (41%), Gaps = 7/145 (4%)
Frame = +1
Query: 112 CENATSLSLMIDSLLATYDRDSPPD---SKIVVNLTLHLRHAN-IRESESTVRIQADLQM 279
C N + ++D +L+ YD P+ + + V +++++ I E I
Sbjct: 48 CANEAVVQKILDRVLSRYDVRLRPNFGGAPVPVRISIYVTSIEQISEMNMDYTITMFFHQ 107
Query: 280 NWIDKRLSWNVGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSN---NGSVS 450
W D RL++ + E+LW PD LN+ D + RV +G+V
Sbjct: 108 TWKDSRLAYYETTLNLTLDYRMHEKLWVPDCYFLNSKDAFVHDVTVENRVFQLHPDGTVR 167
Query: 451 WIKRLDISTPISMQLDNWPNDMQTC 525
+ RL + S+ L +P D Q C
Sbjct: 168 YGIRLTTTAACSLDLHKFPMDKQAC 192
>X15376-1|CAA33437.1| 467|Homo sapiens GABA-A receptor gamma 2
subunit protein.
Length = 467
Score = 44.4 bits (100), Expect = 6e-04
Identities = 37/172 (21%), Positives = 76/172 (44%), Gaps = 9/172 (5%)
Frame = +1
Query: 130 LSLMIDSLLATYDRDSPPDSKIVVNLTLHLRHANIRESESTVRIQADLQM----NWIDKR 297
+++++++LL YD PD + L + N + + ++ + + W D+R
Sbjct: 66 VTVILNNLLEGYDNKLRPDIGVKPTLIHTDMYVNSIGPVNAINMEYTIDIFFAQMWYDRR 125
Query: 298 LSWN--VGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYAL---RARVSNNGSVSWIKR 462
L +N + ++ +V ++W PD N+ A R+ N+G V + R
Sbjct: 126 LKFNSTIKVLRLNSNMVG--KIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYSLR 183
Query: 463 LDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDQRIYXMFESRXW 618
L I +QL N+P D +C +F S + +E+ + + + ++R W
Sbjct: 184 LTIDAECQLQLHNFPMDEHSCPLEFSSYGYPREEIVYQWKRSSVEVGDTRSW 235
>Z93848-1|CAI41994.1| 376|Homo sapiens glycine receptor, alpha 4
protein.
Length = 376
Score = 44.0 bits (99), Expect = 8e-04
Identities = 31/135 (22%), Positives = 58/135 (42%), Gaps = 4/135 (2%)
Frame = +1
Query: 181 PDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWN-VGEWGCSTWLVSSERL 357
P + N+ ++ ++I ++ R+ L+ W D RLS+ + + +
Sbjct: 28 PPVNVTCNIFIN-SFSSITKTTMDYRVNVFLRQQWNDPRLSYREYPDDSLDLDPSMLDSI 86
Query: 358 WRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCT 528
W+PD+ N + R+ NG+V + RL + M L N+P D+QTCT
Sbjct: 87 WKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLILSCLMDLKNFPMDIQTCT 146
Query: 529 FKFGSRMHNSDEMDF 573
+ S + ++ F
Sbjct: 147 MQLESFGYTMKDLVF 161
>AL049610-1|CAI42158.1| 376|Homo sapiens glycine receptor, alpha 4
protein.
Length = 376
Score = 44.0 bits (99), Expect = 8e-04
Identities = 31/135 (22%), Positives = 58/135 (42%), Gaps = 4/135 (2%)
Frame = +1
Query: 181 PDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWN-VGEWGCSTWLVSSERL 357
P + N+ ++ ++I ++ R+ L+ W D RLS+ + + +
Sbjct: 28 PPVNVTCNIFIN-SFSSITKTTMDYRVNVFLRQQWNDPRLSYREYPDDSLDLDPSMLDSI 86
Query: 358 WRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCT 528
W+PD+ N + R+ NG+V + RL + M L N+P D+QTCT
Sbjct: 87 WKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLILSCLMDLKNFPMDIQTCT 146
Query: 529 FKFGSRMHNSDEMDF 573
+ S + ++ F
Sbjct: 147 MQLESFGYTMKDLVF 161
>BC114967-1|AAI14968.1| 366|Homo sapiens GLRA1 protein protein.
Length = 366
Score = 43.6 bits (98), Expect = 0.001
Identities = 27/110 (24%), Positives = 50/110 (45%), Gaps = 4/110 (3%)
Frame = +1
Query: 256 RIQADLQMNWIDKRLSWN-VGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---A 423
R+ L+ W D RL++N + + +W+PD+ N +
Sbjct: 4 RVNIFLRQQWNDPRLAYNEYPDDSLDLDPSMLDSIWKPDLFFANEKGAHFHEITTDNKLL 63
Query: 424 RVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDF 573
R+S NG+V + R+ ++ M L N+P D+QTC + S + +++ F
Sbjct: 64 RISRNGNVLYSIRITLTLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIF 113
>BC031087-1|AAH31087.1| 465|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, gamma 1 protein.
Length = 465
Score = 43.6 bits (98), Expect = 0.001
Identities = 36/170 (21%), Positives = 69/170 (40%), Gaps = 7/170 (4%)
Frame = +1
Query: 130 LSLMIDSLLATYDRDSPPDSKI---VVNLTLHLRHAN-IRESESTVRIQADLQMNWIDKR 297
++ +++SLL YD PD + V+ +++ + I W D R
Sbjct: 64 ITQILNSLLQGYDNKLRPDIGVRPTVIETDVYVNSIGPVDPINMEYTIDIIFAQTWFDSR 123
Query: 298 LSWNVGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLD 468
L +N ++W PD N+ + A R+ N+G V + RL
Sbjct: 124 LKFNSTMKVLMLNSNMVGKIWIPDTFFRNSRKSDAHWITTPNRLLRIWNDGRVLYTLRLT 183
Query: 469 ISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDQRIYXMFESRXW 618
I+ +QL N+P D +C +F S + +E+++ + + + + W
Sbjct: 184 INAECYLQLHNFPMDEHSCPLEFSSYGYPKNEIEYKWKKPSVEVADPKYW 233
>AB209359-1|BAD92596.1| 533|Homo sapiens cholinergic receptor,
nicotinic, alpha polypeptide 4 precursor variant
protein.
Length = 533
Score = 37.9 bits (84), Expect = 0.050
Identities = 20/74 (27%), Positives = 34/74 (45%)
Frame = +1
Query: 355 LWRPDVVLLNAAATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFK 534
LW +A A + +A + ++G V W + S+ + +P D Q CT K
Sbjct: 25 LWLCCCTFTSADGDFAVTHLTKAHLFHDGRVQWTPPAIYKSSCSIDVTFFPFDQQNCTMK 84
Query: 535 FGSRMHNSDEMDFV 576
FGS ++ ++D V
Sbjct: 85 FGSWTYDKAKIDLV 98
>BC096291-1|AAH96291.1| 556|Homo sapiens CHRNA4 protein protein.
Length = 556
Score = 37.1 bits (82), Expect = 0.087
Identities = 19/62 (30%), Positives = 33/62 (53%), Gaps = 4/62 (6%)
Frame = +1
Query: 403 GDYAL----RARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 570
GD+A+ +A + ++G V W + S+ + +P D Q CT KFGS ++ ++D
Sbjct: 60 GDFAVTHLTKAHLFHDGRVQWTPPAIYKSSCSIDVTFFPFDQQNCTMKFGSWTYDKAKID 119
Query: 571 FV 576
V
Sbjct: 120 LV 121
>U83981-1|AAC25631.1| 674|Homo sapiens apoptosis associated protein
protein.
Length = 674
Score = 31.1 bits (67), Expect = 5.7
Identities = 17/46 (36%), Positives = 22/46 (47%), Gaps = 1/46 (2%)
Frame = -3
Query: 430 IHGRGERSPRRWLQPRLAVPRQASTSVPRTPAKCCSP-TPLRSNSV 296
I+ GE+ P W PRL + Q P TP P TPL++ V
Sbjct: 511 IYVPGEKPPPPWAPPRLPLRLQRRLKRPETPTHDPDPETPLKARKV 556
>CR457259-1|CAG33540.1| 674|Homo sapiens PPP1R15A protein.
Length = 674
Score = 31.1 bits (67), Expect = 5.7
Identities = 17/46 (36%), Positives = 22/46 (47%), Gaps = 1/46 (2%)
Frame = -3
Query: 430 IHGRGERSPRRWLQPRLAVPRQASTSVPRTPAKCCSP-TPLRSNSV 296
I+ GE+ P W PRL + Q P TP P TPL++ V
Sbjct: 511 IYVPGEKPPPPWAPPRLPLRLQRRLKRPETPTHDPDPETPLKARKV 556
>BC003067-1|AAH03067.1| 674|Homo sapiens protein phosphatase 1,
regulatory (inhibitor) subunit 15A protein.
Length = 674
Score = 31.1 bits (67), Expect = 5.7
Identities = 17/46 (36%), Positives = 22/46 (47%), Gaps = 1/46 (2%)
Frame = -3
Query: 430 IHGRGERSPRRWLQPRLAVPRQASTSVPRTPAKCCSP-TPLRSNSV 296
I+ GE+ P W PRL + Q P TP P TPL++ V
Sbjct: 511 IYVPGEKPPPPWAPPRLPLRLQRRLKRPETPTHDPDPETPLKARKV 556
>AK001361-1|BAA91649.1| 674|Homo sapiens protein ( Homo sapiens
cDNA FLJ10499 fis, clone NT2RP2000346, weakly similar to
MYELOID DIFFERENTIATION PRIMARY RESPONSE PROTEIN MYD116.
).
Length = 674
Score = 31.1 bits (67), Expect = 5.7
Identities = 17/46 (36%), Positives = 22/46 (47%), Gaps = 1/46 (2%)
Frame = -3
Query: 430 IHGRGERSPRRWLQPRLAVPRQASTSVPRTPAKCCSP-TPLRSNSV 296
I+ GE+ P W PRL + Q P TP P TPL++ V
Sbjct: 511 IYVPGEKPPPPWAPPRLPLRLQRRLKRPETPTHDPDPETPLKARKV 556
>AK122582-1|BAC56923.1| 1383|Homo sapiens FLJ00269 protein protein.
Length = 1383
Score = 30.3 bits (65), Expect = 10.0
Identities = 13/38 (34%), Positives = 18/38 (47%)
Frame = -3
Query: 427 HGRGERSPRRWLQPRLAVPRQASTSVPRTPAKCCSPTP 314
HG + SP W Q + + P + P P +CCS P
Sbjct: 256 HGGRDCSPTCWEQGKCSGPAEQEKRGPSFPKECCSQGP 293
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 115,136,600
Number of Sequences: 237096
Number of extensions: 2548342
Number of successful extensions: 10066
Number of sequences better than 10.0: 183
Number of HSP's better than 10.0 without gapping: 9509
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 9915
length of database: 76,859,062
effective HSP length: 90
effective length of database: 55,520,422
effective search space used: 11659288620
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
- SilkBase 1999-2023 -