BLASTX 2.2.12 [Aug-07-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= BmNP01_FL5_J04 (874 letters) Database: uniref50 1,657,284 sequences; 575,637,011 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value UniRef50_Q6NP10 Cluster: LD13390p; n=7; Eukaryota|Rep: LD13390p ... 303 4e-81 UniRef50_Q9UBR1 Cluster: Beta-ureidopropionase; n=42; root|Rep: ... 294 2e-78 UniRef50_O61697 Cluster: Putative beta-ureidopropionase; n=1; Ma... 283 3e-75 UniRef50_A7SG03 Cluster: Predicted protein; n=1; Nematostella ve... 244 2e-63 UniRef50_UPI0000DC0724 Cluster: ureidopropionase, beta; n=1; Rat... 217 3e-55 UniRef50_Q5L031 Cluster: Beta-alanine synthase; n=19; Bacteria|R... 121 2e-26 UniRef50_Q972L1 Cluster: 281aa long hypothetical beta-ureidoprop... 87 7e-16 UniRef50_Q6AHZ8 Cluster: Putative uncharacterized protein DKFZp7... 85 3e-15 UniRef50_A6DKQ0 Cluster: Carbon-nitrogen hydrolase family protei... 84 5e-15 UniRef50_Q97RA3 Cluster: Carbon-nitrogen hydrolase family protei... 83 1e-14 UniRef50_A4B9A7 Cluster: Probable hydratase; n=2; Bacteria|Rep: ... 81 4e-14 UniRef50_Q1IQA8 Cluster: Nitrilase/cyanide hydratase and apolipo... 79 2e-13 UniRef50_Q9UYV8 Cluster: Beta ureidopropionase; n=4; Thermococca... 78 3e-13 UniRef50_Q9ABL5 Cluster: Hydrolase, carbon-nitrogen family; n=13... 77 8e-13 UniRef50_Q2S196 Cluster: Hydrolase, carbon-nitrogen family; n=1;... 73 7e-12 UniRef50_Q1GTC5 Cluster: Nitrilase/cyanide hydratase and apolipo... 73 7e-12 UniRef50_A7I5W9 Cluster: Porphyromonas-type peptidyl-arginine de... 71 4e-11 UniRef50_Q972X1 Cluster: 264aa long hypothetical beta-ureidoprop... 70 7e-11 UniRef50_Q8VYF5 Cluster: N-carbamoylputrescine amidase; n=60; ce... 70 7e-11 UniRef50_Q89413 Cluster: A78R protein; n=6; Chlorovirus|Rep: A78... 70 9e-11 UniRef50_A5C5V4 Cluster: Putative uncharacterized protein; n=1; ... 69 1e-10 UniRef50_A7I2D9 Cluster: Hydrolase, carbon-nitrogen family; n=1;... 69 2e-10 UniRef50_Q7M8G2 Cluster: HYDROLASE-Predicted amidohydrolase; n=5... 67 5e-10 UniRef50_A6QC56 Cluster: Hydrolase; n=2; Bacteria|Rep: Hydrolase... 66 8e-10 UniRef50_Q606Z9 Cluster: Hydrolase, carbon-nitrogen family; n=38... 66 1e-09 UniRef50_A6BCC3 Cluster: Carbon-nitrogen hydrolase family protei... 64 3e-09 UniRef50_O59829 Cluster: Nitrilase; n=2; cellular organisms|Rep:... 64 4e-09 UniRef50_Q54JM9 Cluster: Putative uncharacterized protein; n=1; ... 63 8e-09 UniRef50_A0QWL8 Cluster: Carbon-nitrogen hydrolase family protei... 61 3e-08 UniRef50_A6CCK5 Cluster: Putative uncharacterized protein; n=1; ... 61 4e-08 UniRef50_A0TTW8 Cluster: Nitrilase/cyanide hydratase and apolipo... 60 7e-08 UniRef50_Q8RUF8 Cluster: AT5g12040/F14F18_210; n=9; Magnoliophyt... 60 7e-08 UniRef50_A6DDT2 Cluster: HYDROLASE-Predicted amidohydrolase; n=1... 60 1e-07 UniRef50_A3H7D3 Cluster: Nitrilase/cyanide hydratase and apolipo... 60 1e-07 UniRef50_Q44185 Cluster: N-carbamoyl-D-amino acid hydrolase; n=1... 59 1e-07 UniRef50_A3LZY2 Cluster: Aliphatic nitrilase; n=1; Pichia stipit... 57 5e-07 UniRef50_Q2AH52 Cluster: Nitrilase/cyanide hydratase and apolipo... 56 9e-07 UniRef50_A7GE66 Cluster: Hydrolase, carbon-nitrogen family; n=13... 56 9e-07 UniRef50_Q5KJU9 Cluster: Hydrolase, putative; n=1; Filobasidiell... 56 9e-07 UniRef50_Q6N746 Cluster: Nitrilase/cyanide hydratase and apolipo... 54 4e-06 UniRef50_Q6N4F1 Cluster: Possible amidohydrolase; n=2; Rhodopseu... 54 4e-06 UniRef50_A6TPX2 Cluster: Nitrilase/cyanide hydratase and apolipo... 54 4e-06 UniRef50_Q2NHR0 Cluster: Predicted amidohydrolase; n=1; Methanos... 54 4e-06 UniRef50_Q0AX54 Cluster: N-carbamoyl-D-amino acid amidohydrolase... 54 6e-06 UniRef50_A0QPL8 Cluster: Hydrolase, carbon-nitrogen family prote... 54 6e-06 UniRef50_A2BNC1 Cluster: Predicted amidohydrolase; n=1; Hyperthe... 54 6e-06 UniRef50_A4J4S3 Cluster: Nitrilase/cyanide hydratase and apolipo... 53 8e-06 UniRef50_A4SZC4 Cluster: Nitrilase/cyanide hydratase and apolipo... 52 3e-05 UniRef50_A2XD42 Cluster: Putative uncharacterized protein; n=2; ... 51 4e-05 UniRef50_Q9KE11 Cluster: BH1047 protein; n=1; Bacillus haloduran... 48 2e-04 UniRef50_A4M5M1 Cluster: Nitrilase/cyanide hydratase and apolipo... 48 2e-04 UniRef50_A6CFF3 Cluster: Putative nitrilase; n=1; Planctomyces m... 48 3e-04 UniRef50_Q84FR7 Cluster: D-N-carbamoylase; n=1; Arthrobacter cry... 47 7e-04 UniRef50_A7DPX6 Cluster: Nitrilase/cyanide hydratase and apolipo... 46 0.002 UniRef50_A0RYH6 Cluster: Amidohydrolase; n=1; Cenarchaeum symbio... 46 0.002 UniRef50_Q89E80 Cluster: Bll7207 protein; n=1; Bradyrhizobium ja... 45 0.002 UniRef50_A6T2L9 Cluster: Nitrilase; n=1; Janthinobacterium sp. M... 45 0.002 UniRef50_O30121 Cluster: Putative uncharacterized protein; n=1; ... 45 0.002 UniRef50_Q4K4P2 Cluster: Hydrolase, carbon-nitrogen family; n=5;... 45 0.003 UniRef50_Q6JHR5 Cluster: Aliphatic amidase; n=1; Saccharopolyspo... 44 0.004 UniRef50_Q1PXD4 Cluster: Similar to N-carbamoyl-D-amino acid hyd... 44 0.004 UniRef50_A3ZLM3 Cluster: Putative nitrilase; n=1; Blastopirellul... 44 0.004 UniRef50_A6TL48 Cluster: Nitrilase/cyanide hydratase and apolipo... 44 0.005 UniRef50_A6CCB9 Cluster: Predicted amidohydrolase; n=1; Planctom... 44 0.005 UniRef50_Q6AMZ4 Cluster: Putative uncharacterized protein; n=1; ... 43 0.009 UniRef50_Q0LQX0 Cluster: Nitrilase/cyanide hydratase and apolipo... 43 0.009 UniRef50_UPI000051A529 Cluster: PREDICTED: similar to Nitrilase ... 43 0.012 UniRef50_A2BKF1 Cluster: Predicted amidohydrolase; n=1; Hyperthe... 43 0.012 UniRef50_Q72HE8 Cluster: Beta-ureidopropionase; n=2; Thermus the... 42 0.015 UniRef50_Q1AWK1 Cluster: Nitrilase/cyanide hydratase and apolipo... 42 0.015 UniRef50_Q8W0T9 Cluster: Putative uncharacterized protein SB35P0... 42 0.015 UniRef50_A3EVA0 Cluster: NAD synthase; n=4; Bacteria|Rep: NAD sy... 42 0.027 UniRef50_A0L7H1 Cluster: Nitrilase/cyanide hydratase and apolipo... 42 0.027 UniRef50_Q6L0F7 Cluster: Carbon-nitrogen hydrolase family; n=2; ... 42 0.027 UniRef50_A1HPP3 Cluster: Nitrilase/cyanide hydratase and apolipo... 41 0.036 UniRef50_Q8ZVX6 Cluster: Nitrilase, conjectural; n=4; Pyrobaculu... 41 0.036 UniRef50_A6Q8M5 Cluster: Carbon-nitrogen hydrolase family protei... 41 0.047 UniRef50_A5GU42 Cluster: Nitrilase-related protein; n=1; Synecho... 41 0.047 UniRef50_A3M2Z7 Cluster: Putative glutamine-dependent NAD(+) syn... 41 0.047 UniRef50_UPI0000E472D9 Cluster: PREDICTED: similar to Ureidoprop... 40 0.062 UniRef50_Q5LLB2 Cluster: Nitrilase family protein; n=7; Bacteria... 40 0.062 UniRef50_Q5MD29 Cluster: CtaJ; n=2; Cystobacteraceae|Rep: CtaJ -... 40 0.062 UniRef50_Q1F028 Cluster: Nitrilase/cyanide hydratase and apolipo... 40 0.062 UniRef50_A5V6Z2 Cluster: Nitrilase/cyanide hydratase and apolipo... 40 0.062 UniRef50_A4WA35 Cluster: Nitrilase/cyanide hydratase and apolipo... 40 0.062 UniRef50_Q2JDM2 Cluster: Nitrilase/cyanide hydratase and apolipo... 40 0.083 UniRef50_A7FDR9 Cluster: Hydrolase, carbon-nitrogen family prote... 40 0.083 UniRef50_A0JSY8 Cluster: Nitrilase/cyanide hydratase and apolipo... 40 0.083 UniRef50_A5AAF3 Cluster: Contig An02c0310, complete genome; n=5;... 40 0.083 UniRef50_Q9HIW8 Cluster: Nitrilase related protein; n=2; Thermop... 40 0.083 UniRef50_Q6TGW8 Cluster: Nit protein 2; n=22; Fungi/Metazoa grou... 40 0.11 UniRef50_Q75TH8 Cluster: Putative uncharacterized protein GSB07;... 40 0.11 UniRef50_Q1AZG5 Cluster: Nitrilase; n=1; Rubrobacter xylanophilu... 40 0.11 UniRef50_Q15ZG7 Cluster: Nitrilase/cyanide hydratase and apolipo... 40 0.11 UniRef50_Q8WUF0 Cluster: Nitrilase family member 2; n=28; cellul... 40 0.11 UniRef50_Q8TPH5 Cluster: Carbon-nitrogen hydrolase; n=1; Methano... 40 0.11 UniRef50_Q5V604 Cluster: Nitrilase; n=2; Halobacteriaceae|Rep: N... 40 0.11 UniRef50_Q3W243 Cluster: GCN5-related N-acetyltransferase:AIR sy... 39 0.14 UniRef50_UPI0000E1FE2F Cluster: PREDICTED: similar to Nitrilase ... 39 0.19 UniRef50_A1HQ26 Cluster: Nitrilase/cyanide hydratase and apolipo... 39 0.19 UniRef50_Q4WEA8 Cluster: Hydrolase, carbon-nitrogen family, puta... 39 0.19 UniRef50_Q6RWQ0 Cluster: Nitrilase; n=3; uncultured organism|Rep... 38 0.25 UniRef50_Q8KCC8 Cluster: Carbon-nitrogen hydrolase family protei... 38 0.25 UniRef50_A7DA57 Cluster: Nitrilase/cyanide hydratase and apolipo... 38 0.25 UniRef50_A5WCY0 Cluster: Nitrilase/cyanide hydratase and apolipo... 38 0.25 UniRef50_A4YP30 Cluster: N-carbamoyl-D-amino acid hydrolase; n=4... 38 0.25 UniRef50_A0LQU6 Cluster: Nitrilase/cyanide hydratase and apolipo... 38 0.25 UniRef50_Q9ZMC7 Cluster: Putative; n=6; Campylobacterales|Rep: P... 38 0.33 UniRef50_A6DBX4 Cluster: Nitrilase/cyanide hydratase and apolipo... 38 0.33 UniRef50_A0J1U1 Cluster: Nitrilase/cyanide hydratase and apolipo... 38 0.33 UniRef50_A0LH50 Cluster: Nitrilase/cyanide hydratase and apolipo... 38 0.44 UniRef50_Q2QQ94 Cluster: Hydrolase, carbon-nitrogen family prote... 38 0.44 UniRef50_O25836 Cluster: Formamidase; n=17; Bacteria|Rep: Formam... 38 0.44 UniRef50_Q74FF8 Cluster: Hydrolase, carbon-nitrogen family; n=6;... 37 0.58 UniRef50_A4YSE7 Cluster: N-carbamoyl-D-amino acid hydrolase; n=1... 37 0.77 UniRef50_Q4Q8W4 Cluster: Nitrilase, putative; n=6; Trypanosomati... 37 0.77 UniRef50_Q23384 Cluster: Putative uncharacterized protein nit-1;... 37 0.77 UniRef50_Q0LC17 Cluster: NAD+ synthetase; n=1; Herpetosiphon aur... 36 1.0 UniRef50_Q04W18 Cluster: Amidohydrolase; n=4; Leptospira|Rep: Am... 36 1.0 UniRef50_Q6RWQ5 Cluster: Nitrilase; n=1; uncultured organism|Rep... 36 1.3 UniRef50_Q12DE7 Cluster: Nitrilase/cyanide hydratase and apolipo... 36 1.8 UniRef50_A0U0W3 Cluster: Nitrilase/cyanide hydratase and apolipo... 36 1.8 UniRef50_A0CJZ7 Cluster: Chromosome undetermined scaffold_2, who... 36 1.8 UniRef50_Q5K7Z3 Cluster: Expressed protein; n=1; Filobasidiella ... 36 1.8 UniRef50_Q6RWN7 Cluster: Nitrilase; n=21; root|Rep: Nitrilase - ... 35 2.3 UniRef50_Q4KB18 Cluster: Hydrolase, carbon-nitrogen family; n=2;... 35 2.3 UniRef50_A4M7Y7 Cluster: Nitrilase/cyanide hydratase and apolipo... 35 2.3 UniRef50_Q7QAW0 Cluster: ENSANGP00000011026; n=2; Culicidae|Rep:... 35 2.3 UniRef50_Q83AQ3 Cluster: Putative uncharacterized protein; n=5; ... 35 3.1 UniRef50_Q2RL06 Cluster: NAD+ synthetase; n=1; Moorella thermoac... 35 3.1 UniRef50_Q18UU7 Cluster: Nitrilase/cyanide hydratase and apolipo... 35 3.1 UniRef50_Q0EPQ3 Cluster: Nitrilase/cyanide hydratase and apolipo... 35 3.1 UniRef50_Q9X0Y0 Cluster: Probable glutamine-dependent NAD(+) syn... 35 3.1 UniRef50_Q3A713 Cluster: Predicted amidohydrolase family protein... 34 4.1 UniRef50_Q2ADS5 Cluster: Nitrilase/cyanide hydratase and apolipo... 34 4.1 UniRef50_Q1IIQ6 Cluster: Sigma-24, ECF subfamily; n=1; Acidobact... 34 4.1 UniRef50_A6FX13 Cluster: Nitrilase/cyanide hydratase and apolipo... 34 4.1 UniRef50_Q7QKM8 Cluster: ENSANGP00000017134; n=5; Culicidae|Rep:... 34 4.1 UniRef50_A2R283 Cluster: Contig An13c0120, complete genome; n=2;... 34 4.1 UniRef50_Q4JAH2 Cluster: Conserved protein; n=4; Sulfolobaceae|R... 34 4.1 UniRef50_Q86X76 Cluster: Nitrilase homolog 1; n=29; Eumetazoa|Re... 34 4.1 UniRef50_Q9ADI8 Cluster: NAD(+) synthase; n=12; Bacteria|Rep: NA... 34 5.4 UniRef50_A1SE99 Cluster: Nitrilase/cyanide hydratase and apolipo... 34 5.4 UniRef50_A2D8H0 Cluster: Putative uncharacterized protein; n=1; ... 34 5.4 UniRef50_Q2GWJ9 Cluster: Putative uncharacterized protein; n=1; ... 34 5.4 UniRef50_Q8TPH6 Cluster: Putative uncharacterized protein; n=1; ... 34 5.4 UniRef50_A5UTD2 Cluster: Nitrilase/cyanide hydratase and apolipo... 33 7.2 UniRef50_Q9LE50 Cluster: Nitrilase 1 like protein; n=2; Arabidop... 33 7.2 UniRef50_Q17CS4 Cluster: Nitrilase, putative; n=3; Culicidae|Rep... 33 7.2 UniRef50_A0D532 Cluster: Chromosome undetermined scaffold_38, wh... 33 7.2 UniRef50_Q0UT99 Cluster: Putative uncharacterized protein; n=1; ... 33 7.2 UniRef50_Q9V206 Cluster: Putative uncharacterized protein; n=1; ... 33 7.2 UniRef50_Q1FPL1 Cluster: Nitrilase/cyanide hydratase and apolipo... 33 9.5 UniRef50_A0J1T6 Cluster: Nitrilase/cyanide hydratase and apolipo... 33 9.5 UniRef50_Q8IIP2 Cluster: Putative uncharacterized protein; n=1; ... 33 9.5 UniRef50_Q6XUA7 Cluster: Neuraminidase; n=3339; root|Rep: Neuram... 33 9.5 >UniRef50_Q6NP10 Cluster: LD13390p; n=7; Eukaryota|Rep: LD13390p - Drosophila melanogaster (Fruit fly) Length = 408 Score = 303 bits (744), Expect = 4e-81 Identities = 140/250 (56%), Positives = 174/250 (69%) Frame = +1 Query: 64 ETHSLESIINNNLTGRDLEEFNRIHFGRRNNLEIKLKESSIXXXXXXXXXXXXXXFPAKD 243 E +L + +L +L+E RI +G + ++L S+ F A++ Sbjct: 27 ELKNLNDCLEKHLPPDELKEVKRILYGVEEDQTLELPTSAKDIAEQNGFDIKGYRFTARE 86 Query: 244 EQTRPPRIVKVGIIQHSIAVPTDRPVNEQKKAIFNKVKKIIDVAGQEGVNIICFQELWNM 423 EQTR RIV+VG IQ+SI +PT P+ +Q++AI+NKVK +I A + G NI+C QE W M Sbjct: 87 EQTRKRRIVRVGAIQNSIVIPTTAPIEKQREAIWNKVKTMIKAAAEAGCNIVCTQEAWTM 146 Query: 424 PFAFCTREKQPWCEFAESAEDGPTTTFLRELAIRYAMVIVSSILERDEKHSDILWNTAVV 603 PFAFCTREK PWCEFAE AE+GPTT L ELA Y MVI+ SILERD +H + +WNTAVV Sbjct: 147 PFAFCTREKFPWCEFAEEAENGPTTKMLAELAKAYNMVIIHSILERDMEHGETIWNTAVV 206 Query: 604 ISDTGNVIGKHRKNHIPRVGDFNESNYYMEGNTGHPVFAXRYGKIAVXICFGRDHVLNWM 783 IS++G +GKHRKNHIPRVGDFNES YYMEGNTGHPVF +GK+AV IC+GR H NWM Sbjct: 207 ISNSGRYLGKHRKNHIPRVGDFNESTYYMEGNTGHPVFETEFGKLAVNICYGRHHPQNWM 266 Query: 784 MFGXNGXEIV 813 MFG NG EIV Sbjct: 267 MFGLNGAEIV 276 >UniRef50_Q9UBR1 Cluster: Beta-ureidopropionase; n=42; root|Rep: Beta-ureidopropionase - Homo sapiens (Human) Length = 384 Score = 294 bits (721), Expect = 2e-78 Identities = 137/250 (54%), Positives = 173/250 (69%) Frame = +1 Query: 64 ETHSLESIINNNLTGRDLEEFNRIHFGRRNNLEIKLKESSIXXXXXXXXXXXXXXFPAKD 243 E SLE + +L DL+E R+ +G+ ++ L + F A + Sbjct: 5 EWKSLEECLEKHLPLPDLQEVKRVLYGKELR-KLDLPREAFEAASREDFELQGYAFEAAE 63 Query: 244 EQTRPPRIVKVGIIQHSIAVPTDRPVNEQKKAIFNKVKKIIDVAGQEGVNIICFQELWNM 423 EQ R PRIV VG++Q+ I +P + PV EQ A+ ++K I++VA GVNIICFQE W M Sbjct: 64 EQLRRPRIVHVGLVQNRIPLPANAPVAEQVSALHRRIKAIVEVAAMCGVNIICFQEAWTM 123 Query: 424 PFAFCTREKQPWCEFAESAEDGPTTTFLRELAIRYAMVIVSSILERDEKHSDILWNTAVV 603 PFAFCTREK PW EFAESAEDGPTT F ++LA + MV+VS ILERD +H D+LWNTAVV Sbjct: 124 PFAFCTREKLPWTEFAESAEDGPTTRFCQKLAKNHDMVVVSPILERDSEHGDVLWNTAVV 183 Query: 604 ISDTGNVIGKHRKNHIPRVGDFNESNYYMEGNTGHPVFAXRYGKIAVXICFGRDHVLNWM 783 IS++G V+GK RKNHIPRVGDFNES YYMEGN GHPVF ++G+IAV IC+GR H LNW+ Sbjct: 184 ISNSGAVLGKTRKNHIPRVGDFNESTYYMEGNLGHPVFQTQFGRIAVNICYGRHHPLNWL 243 Query: 784 MFGXNGXEIV 813 M+ NG EI+ Sbjct: 244 MYSINGAEII 253 >UniRef50_O61697 Cluster: Putative beta-ureidopropionase; n=1; Manduca sexta|Rep: Putative beta-ureidopropionase - Manduca sexta (Tobacco hawkmoth) (Tobacco hornworm) Length = 185 Score = 283 bits (695), Expect = 3e-75 Identities = 135/184 (73%), Positives = 153/184 (83%) Frame = +1 Query: 58 ENETHSLESIINNNLTGRDLEEFNRIHFGRRNNLEIKLKESSIXXXXXXXXXXXXXXFPA 237 +NET SLE+II NNL+GRDL+EFNRI++GR+N+LE+KLK+SS+ FPA Sbjct: 1 DNETQSLEAIIENNLSGRDLDEFNRIYYGRKNHLEVKLKDSSLAAAKEADFEVAAYAFPA 60 Query: 238 KDEQTRPPRIVKVGIIQHSIAVPTDRPVNEQKKAIFNKVKKIIDVAGQEGVNIICFQELW 417 K EQTRPPRIVKVG+IQHSI PTDRPVNEQKKAIF+KVKKIIDVAGQEGVNIICFQELW Sbjct: 61 KKEQTRPPRIVKVGVIQHSIGAPTDRPVNEQKKAIFDKVKKIIDVAGQEGVNIICFQELW 120 Query: 418 NMPFAFCTREKQPWCEFAESAEDGPTTTFLRELAIRYAMVIVSSILERDEKHSDILWNTA 597 NMPFAFCTREKQPWCEFAESAE+GPTT FLRELA++Y+MVIVSSIL+ TA Sbjct: 121 NMPFAFCTREKQPWCEFAESAEEGPTTRFLRELAMKYSMVIVSSILDVMRNMLISCGTTA 180 Query: 598 VVIS 609 VVIS Sbjct: 181 VVIS 184 >UniRef50_A7SG03 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 359 Score = 244 bits (597), Expect = 2e-63 Identities = 115/225 (51%), Positives = 147/225 (65%) Frame = +1 Query: 55 MENETHSLESIINNNLTGRDLEEFNRIHFGRRNNLEIKLKESSIXXXXXXXXXXXXXXFP 234 M E SL + NL DL+E RI +G + ++ L +++ Sbjct: 1 MAAEFESLNKTLEKNLPAEDLKEVKRILYGNPVS-DLSLPAAAVSVAAELDFELAGYKID 59 Query: 235 AKDEQTRPPRIVKVGIIQHSIAVPTDRPVNEQKKAIFNKVKKIIDVAGQEGVNIICFQEL 414 A E+ R PR+V++G +Q+ I PT+ P+ +Q++ + N++K I+ A VN+ICFQE Sbjct: 60 AAAEELRQPRLVRIGAVQNKIVEPTNMPIAKQREGLHNRMKDIVKAAALSKVNVICFQEC 119 Query: 415 WNMPFAFCTREKQPWCEFAESAEDGPTTTFLRELAIRYAMVIVSSILERDEKHSDILWNT 594 W MPFAFCTREKQPW EFAESAEDGPT +E A RY MVIVS ILERD H +ILWNT Sbjct: 120 WTMPFAFCTREKQPWTEFAESAEDGPTVRLCQEWAKRYNMVIVSPILERDHTHQEILWNT 179 Query: 595 AVVISDTGNVIGKHRKNHIPRVGDFNESNYYMEGNTGHPVFAXRY 729 AV+IS+TG VIGK RKNHIPRVGDFNES YYMEG+ GH VF ++ Sbjct: 180 AVIISNTGEVIGKTRKNHIPRVGDFNESTYYMEGDMGHQVFQTQF 224 >UniRef50_UPI0000DC0724 Cluster: ureidopropionase, beta; n=1; Rattus norvegicus|Rep: ureidopropionase, beta - Rattus norvegicus Length = 392 Score = 217 bits (530), Expect = 3e-55 Identities = 106/250 (42%), Positives = 151/250 (60%) Frame = +1 Query: 64 ETHSLESIINNNLTGRDLEEFNRIHFGRRNNLEIKLKESSIXXXXXXXXXXXXXXFPAKD 243 E SLE + +L DL + RI +G++ + L ++ F A Sbjct: 5 EWQSLEQCLEKHLPPDDLSQVKRILYGKQTR-NLDLPRKALEAASERNFELKGYAFGAAK 63 Query: 244 EQTRPPRIVKVGIIQHSIAVPTDRPVNEQKKAIFNKVKKIIDVAGQEGVNIICFQELWNM 423 EQ R P+IV+VG++Q+ I +PT PV EQ A+ ++++I +VA GVNIICFQE WNM Sbjct: 64 EQQRCPQIVRVGLVQNRIPLPTSAPVAEQVSALHKRIEEIAEVAAMCGVNIICFQEAWNM 123 Query: 424 PFAFCTREKQPWCEFAESAEDGPTTTFLRELAIRYAMVIVSSILERDEKHSDILWNTAVV 603 PFAFCTREK PW EFAESAEDG TT F ++ ++ + +++ L + + WN+ + Sbjct: 124 PFAFCTREKLPWTEFAESAEDGLTTRFCQKGKFQHIVCLIAIFLRQSLTLGLVAWNSLDI 183 Query: 604 ISDTGNVIGKHRKNHIPRVGDFNESNYYMEGNTGHPVFAXRYGKIAVXICFGRDHVLNWM 783 + G V + + H P V D++ S YYMEGN GHPVF ++G+IAV IC+GR H LNW+ Sbjct: 184 SVNAGLVNARFKDVHHP-VIDYSYSTYYMEGNLGHPVFQTQFGRIAVNICYGRHHPLNWL 242 Query: 784 MFGXNGXEIV 813 M+ NG EI+ Sbjct: 243 MYSVNGAEII 252 >UniRef50_Q5L031 Cluster: Beta-alanine synthase; n=19; Bacteria|Rep: Beta-alanine synthase - Geobacillus kaustophilus Length = 296 Score = 121 bits (292), Expect = 2e-26 Identities = 72/188 (38%), Positives = 96/188 (51%), Gaps = 6/188 (3%) Frame = +1 Query: 268 VKVGIIQHSIAVPTDRPVNEQKKAIFNKVKKIIDVAGQEGVNIICFQELWNMPFAFCTRE 447 V +G+IQ S V D PV K+ K K++ A G IIC QE++ P+ FC + Sbjct: 5 VTIGLIQASHNVHGDEPVEVHKEKAIEKHVKLVKEAKDRGAQIICLQEIFYGPY-FCAEQ 63 Query: 448 KQPWCEFAESAEDGPTTTFLRELAIRYAMVIVSSILERDEKHSDILWNTAVVISDTGNVI 627 W E AE +GPTT +E+A + +VIV I ER+ + +NTA VI G + Sbjct: 64 NTKWYEAAEEIPNGPTTKMFQEIAKQLGVVIVLPIYEREGIAT--YYNTAAVIDADGTYL 121 Query: 628 GKHRKNHIPRVG------DFNESNYYMEGNTGHPVFAXRYGKIAVXICFGRDHVLNWMMF 789 GK+RK HIP VG F E Y+ GN G+ VF + KI V IC+ R + Sbjct: 122 GKYRKQHIPHVGVGNEGCGFWEKFYFKPGNLGYSVFDTAFAKIGVYICYDRHFPEGARIL 181 Query: 790 GXNGXEIV 813 G G EIV Sbjct: 182 GLKGAEIV 189 >UniRef50_Q972L1 Cluster: 281aa long hypothetical beta-ureidopropionase; n=1; Sulfolobus tokodaii|Rep: 281aa long hypothetical beta-ureidopropionase - Sulfolobus tokodaii Length = 281 Score = 86.6 bits (205), Expect = 7e-16 Identities = 54/165 (32%), Positives = 83/165 (50%) Frame = +1 Query: 325 EQKKAIFNKVKKIIDVAGQEGVNIICFQELWNMPFAFCTREKQPWCEFAESAEDGPTTTF 504 E K+A K + A ++G +I + EL+ + F E + + AE EDGPT Sbjct: 16 ESKEANIQKALEYTKAAVKDGAELIVYNELFTTQY-FPATEDPKFFDLAEP-EDGPTVRV 73 Query: 505 LRELAIRYAMVIVSSILERDEKHSDILWNTAVVISDTGNVIGKHRKNHIPRVGDFNESNY 684 E + +Y + ++ +I E D+K I ++TA+ I D G V+GK+RK HIP+V + E Y Sbjct: 74 FAEFSKQYKIGMIITIFEEDKKIKGIYYDTAIFIKD-GKVLGKYRKTHIPQVPGYYEKFY 132 Query: 685 YMEGNTGHPVFAXRYGKIAVXICFGRDHVLNWMMFGXNGXEIVXI 819 + G +PVF KI IC+ R + G +IV I Sbjct: 133 FKPGKE-YPVFDFGGYKIGAVICYDRHFPEGVRILTLKGADIVTI 176 >UniRef50_Q6AHZ8 Cluster: Putative uncharacterized protein DKFZp779O1248; n=1; Homo sapiens|Rep: Putative uncharacterized protein DKFZp779O1248 - Homo sapiens (Human) Length = 186 Score = 84.6 bits (200), Expect = 3e-15 Identities = 50/139 (35%), Positives = 74/139 (53%), Gaps = 1/139 (0%) Frame = +1 Query: 64 ETHSLESIINNNLTGRDLEEFNRIHFGRRNNLEIKLKESSIXXXXXXXXXXXXXXFPAKD 243 E SLE + +L DL+E R+ +G+ ++ L + F A + Sbjct: 5 EWKSLEECLEKHLPLPDLQEVKRVLYGKELR-KLDLPREAFEAASREDFELQGYAFEAAE 63 Query: 244 EQTRPPRIVKVGIIQHSIAVPTDRPVNEQKKAIFNKVKKIIDVAGQEGVNIICFQELWNM 423 EQ R PRIV VG++Q+ I +P + PV EQ A+ ++K I++VA GVNIICFQE W + Sbjct: 64 EQLRRPRIVHVGLVQNRIPLPANAPVAEQVSALHRRIKAIVEVAAMCGVNIICFQEAWIL 123 Query: 424 -PFAFCTREKQPWCEFAES 477 P +E +P C +A S Sbjct: 124 RPH---HQEPRPPCCYAPS 139 >UniRef50_A6DKQ0 Cluster: Carbon-nitrogen hydrolase family protein; n=1; Lentisphaera araneosa HTCC2155|Rep: Carbon-nitrogen hydrolase family protein - Lentisphaera araneosa HTCC2155 Length = 286 Score = 83.8 bits (198), Expect = 5e-15 Identities = 46/133 (34%), Positives = 74/133 (55%) Frame = +1 Query: 358 KIIDVAGQEGVNIICFQELWNMPFAFCTREKQPWCEFAESAEDGPTTTFLRELAIRYAMV 537 K+I A + G NIIC QEL+ + FC + ++A+ + F ++ A + +V Sbjct: 24 KLIADAAKSGANIICTQELFLSNY-FCREQNTEHFQYAQKIDQELLADF-QQCAKNHGVV 81 Query: 538 IVSSILERDEKHSDILWNTAVVISDTGNVIGKHRKNHIPRVGDFNESNYYMEGNTGHPVF 717 + S E E + + +NT+V+I G +GK+RK HIP+ F E Y+ GN G PVF Sbjct: 82 LALSFFE--EALNGVYYNTSVIIDADGTYLGKYRKLHIPQDPYFEEKFYFTPGNLGVPVF 139 Query: 718 AXRYGKIAVXICF 756 ++GKI++ IC+ Sbjct: 140 ETQFGKISLIICW 152 >UniRef50_Q97RA3 Cluster: Carbon-nitrogen hydrolase family protein; n=24; Bacteria|Rep: Carbon-nitrogen hydrolase family protein - Streptococcus pneumoniae Length = 291 Score = 82.6 bits (195), Expect = 1e-14 Identities = 44/153 (28%), Positives = 77/153 (50%) Frame = +1 Query: 355 KKIIDVAGQEGVNIICFQELWNMPFAFCTREKQPWCEFAESAEDGPTTTFLRELAIRYAM 534 ++++ A ++G II EL+ P+ FC + + ++A+S + + +A + Sbjct: 25 ERLVRQAAEQGAQIILLPELFEHPY-FCQERQYDYYQYAQSVAENTAIQHFKVIAKELQV 83 Query: 535 VIVSSILERDEKHSDILWNTAVVISDTGNVIGKHRKNHIPRVGDFNESNYYMEGNTGHPV 714 V+ S E+D ++L+N+ VI G V+G +RK HIP + E Y+ GNTG V Sbjct: 84 VLPISFYEKD---GNVLYNSIAVIDADGEVLGVYRKTHIPDDHYYQEKFYFTPGNTGFKV 140 Query: 715 FAXRYGKIAVXICFGRDHVLNWMMFGXNGXEIV 813 + RY KI + IC+ + NG E++ Sbjct: 141 WNTRYAKIGIGICWDQWFPETARCLALNGAELL 173 >UniRef50_A4B9A7 Cluster: Probable hydratase; n=2; Bacteria|Rep: Probable hydratase - Reinekea sp. MED297 Length = 289 Score = 81.0 bits (191), Expect = 4e-14 Identities = 41/134 (30%), Positives = 70/134 (52%) Frame = +1 Query: 355 KKIIDVAGQEGVNIICFQELWNMPFAFCTREKQPWCEFAESAEDGPTTTFLRELAIRYAM 534 ++++ A G +I QEL+ P+ FC +K+ + FA + +D P +A + Sbjct: 25 ERLVREAAASGAQVILLQELFERPY-FCQHQKEEFRRFATAIDDNPAIAHFAPIARELGV 83 Query: 535 VIVSSILERDEKHSDILWNTAVVISDTGNVIGKHRKNHIPRVGDFNESNYYMEGNTGHPV 714 V+ S E+ + +N+ VV+ G +G +RK HIP + E Y+ G+TG V Sbjct: 84 VLPISFFEQC---GPVAYNSVVVLDADGENLGLYRKTHIPDGPGYCEKFYFTPGDTGFQV 140 Query: 715 FAXRYGKIAVXICF 756 F+ R+G+I V IC+ Sbjct: 141 FSTRFGRIGVGICW 154 >UniRef50_Q1IQA8 Cluster: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; n=52; Bacteria|Rep: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase - Acidobacteria bacterium (strain Ellin345) Length = 303 Score = 78.6 bits (185), Expect = 2e-13 Identities = 53/167 (31%), Positives = 82/167 (49%) Frame = +1 Query: 256 PPRIVKVGIIQHSIAVPTDRPVNEQKKAIFNKVKKIIDVAGQEGVNIICFQELWNMPFAF 435 P +G+IQ S PV E+ A + ++ D A Q G +IC EL+ + F Sbjct: 2 PAEKFTIGLIQMSCG-----PVPEENMA--KALDRVRDAAKQ-GATVICLPELFQTQY-F 52 Query: 436 CTREKQPWCEFAESAEDGPTTTFLRELAIRYAMVIVSSILERDEKHSDILWNTAVVISDT 615 C RE E AES GP T + +LA +V+V+S+ ER + + NTA ++ + Sbjct: 53 CQREDTALFELAESIP-GPATKKMGDLARELGVVVVASLFER--RAPGLYHNTAAILDEA 109 Query: 616 GNVIGKHRKNHIPRVGDFNESNYYMEGNTGHPVFAXRYGKIAVXICF 756 G + G +RK HIP + E Y+ G+ G F ++G I +C+ Sbjct: 110 GALKGIYRKMHIPDDPLYYEKYYFTPGDLGFKTFETKFGPIGTLVCW 156 >UniRef50_Q9UYV8 Cluster: Beta ureidopropionase; n=4; Thermococcaceae|Rep: Beta ureidopropionase - Pyrococcus abyssi Length = 262 Score = 78.2 bits (184), Expect = 3e-13 Identities = 47/138 (34%), Positives = 78/138 (56%) Frame = +1 Query: 343 FNKVKKIIDVAGQEGVNIICFQELWNMPFAFCTREKQPWCEFAESAEDGPTTTFLRELAI 522 ++K +K+I A ++G ++ EL++ + F TRE+ E A+ +G TTTFL ++A Sbjct: 20 YSKAEKLIKEASKQGAQLVVLPELFDTGYNFETREEV--FEIAQKIPEGETTTFLMDVAR 77 Query: 523 RYAMVIVSSILERDEKHSDILWNTAVVISDTGNVIGKHRKNHIPRVGDFNESNYYMEGNT 702 + IV+ E+D D+L+N+AVV+ G IGK+RK H+ + E ++ G+ Sbjct: 78 DTGVYIVAGTAEKD---GDVLYNSAVVVGPRG-FIGKYRKIHL----FYREKFFFEPGDL 129 Query: 703 GHPVFAXRYGKIAVXICF 756 G VF + K+ V ICF Sbjct: 130 GFRVFDLGFMKVGVMICF 147 >UniRef50_Q9ABL5 Cluster: Hydrolase, carbon-nitrogen family; n=13; Bacteria|Rep: Hydrolase, carbon-nitrogen family - Caulobacter crescentus (Caulobacter vibrioides) Length = 292 Score = 76.6 bits (180), Expect = 8e-13 Identities = 44/141 (31%), Positives = 72/141 (51%) Frame = +1 Query: 334 KAIFNKVKKIIDVAGQEGVNIICFQELWNMPFAFCTREKQPWCEFAESAEDGPTTTFLRE 513 +A K + I A +G +I EL+ P+ FC +++ W A + P + Sbjct: 19 QANIKKTEGFIREAASKGAQVILPSELFQGPY-FCVAQEERWFAQAHPWREHPVVKAIAP 77 Query: 514 LAIRYAMVIVSSILERDEKHSDILWNTAVVISDTGNVIGKHRKNHIPRVGDFNESNYYME 693 LA +VI SI ER+ H +N+ V+ G+++G +RK+HIP + E Y+ Sbjct: 78 LAGELGVVIPISIFEREGPH---YFNSLVMADADGSLMGVYRKSHIPDGPGYMEKYYFRP 134 Query: 694 GNTGHPVFAXRYGKIAVXICF 756 G+TG V+ R+G+I V IC+ Sbjct: 135 GDTGFKVWDTRFGRIGVGICW 155 >UniRef50_Q2S196 Cluster: Hydrolase, carbon-nitrogen family; n=1; Salinibacter ruber DSM 13855|Rep: Hydrolase, carbon-nitrogen family - Salinibacter ruber (strain DSM 13855) Length = 283 Score = 73.3 bits (172), Expect = 7e-12 Identities = 45/143 (31%), Positives = 73/143 (51%), Gaps = 6/143 (4%) Frame = +1 Query: 358 KIIDVAGQEGVNIICFQELWNMPFAFCTREKQPWCEFAESAED------GPTTTFLRELA 519 + + A G +++ F EL PF + P E SA D GPTT L E A Sbjct: 23 RAVQAAADAGADLVVFPELSFTPFY----PRVPVAERRRSARDLAEPVPGPTTEALAEAA 78 Query: 520 IRYAMVIVSSILERDEKHSDILWNTAVVISDTGNVIGKHRKNHIPRVGDFNESNYYMEGN 699 +V+V +++ERD + + ++T+ V+ G ++G+ R HI +F+E YY G+ Sbjct: 79 ADGGVVVVFNLMERDGERT---FDTSPVLDADGTLLGRTRMMHITAYENFHEQGYYDPGD 135 Query: 700 TGHPVFAXRYGKIAVXICFGRDH 768 TG PV+ G+I V +C+ R + Sbjct: 136 TGAPVYDTAAGRIGVAVCYDRHY 158 >UniRef50_Q1GTC5 Cluster: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; n=9; Bacteria|Rep: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase - Sphingopyxis alaskensis (Sphingomonas alaskensis) Length = 300 Score = 73.3 bits (172), Expect = 7e-12 Identities = 49/165 (29%), Positives = 80/165 (48%) Frame = +1 Query: 262 RIVKVGIIQHSIAVPTDRPVNEQKKAIFNKVKKIIDVAGQEGVNIICFQELWNMPFAFCT 441 R + V +Q +A+P PV KA V +++ A G II EL+ P+ FC Sbjct: 20 RTITVAALQ--LALPG--PVEPNIKA----VTALVEAAAARGAQIILPPELFEGPY-FCQ 70 Query: 442 REKQPWCEFAESAEDGPTTTFLRELAIRYAMVIVSSILERDEKHSDILWNTAVVISDTGN 621 E++ A + P+ ++ LA + + I +S ERD H +NT +I G Sbjct: 71 VEEEELFATARPTAEHPSVVAMQALAAKCKVAIPTSFFERDGHH---YYNTLAMIGPDGG 127 Query: 622 VIGKHRKNHIPRVGDFNESNYYMEGNTGHPVFAXRYGKIAVXICF 756 ++G +RK+HIP + E Y+ GNTG ++ +I V +C+ Sbjct: 128 IMGTYRKSHIPDGPGYEEKYYFRPGNTGFKIWEVFDTRIGVGVCW 172 >UniRef50_A7I5W9 Cluster: Porphyromonas-type peptidyl-arginine deiminase; n=1; Candidatus Methanoregula boonei 6A8|Rep: Porphyromonas-type peptidyl-arginine deiminase - Methanoregula boonei (strain 6A8) Length = 640 Score = 70.9 bits (166), Expect = 4e-11 Identities = 56/161 (34%), Positives = 77/161 (47%) Frame = +1 Query: 274 VGIIQHSIAVPTDRPVNEQKKAIFNKVKKIIDVAGQEGVNIICFQELWNMPFAFCTREKQ 453 + +IQ I DR +NE ++ +V+K A Q G IC EL+ + F + Sbjct: 8 IALIQMEIGPDPDRNLNEARE----RVEK----AAQNGAQFICLPELFRTRY-FPQQIGT 58 Query: 454 PWCEFAESAEDGPTTTFLRELAIRYAMVIVSSILERDEKHSDILWNTAVVISDTGNVIGK 633 P AE+ T F R +A Y VI+ + ER L N AVVI G++ Sbjct: 59 PVQSLAETIPGESTDVFTR-IAKEYKAVIIVPVFERSPLGH--LENAAVVIDADGSLHAP 115 Query: 634 HRKNHIPRVGDFNESNYYMEGNTGHPVFAXRYGKIAVXICF 756 + K HIP+ F E Y+ GN + V A RYGKIAV IC+ Sbjct: 116 YYKVHIPQDPKFFEKGYFYPGN-HYAVHATRYGKIAVLICY 155 >UniRef50_Q972X1 Cluster: 264aa long hypothetical beta-ureidopropionase; n=1; Sulfolobus tokodaii|Rep: 264aa long hypothetical beta-ureidopropionase - Sulfolobus tokodaii Length = 264 Score = 70.1 bits (164), Expect = 7e-11 Identities = 45/144 (31%), Positives = 73/144 (50%) Frame = +1 Query: 331 KKAIFNKVKKIIDVAGQEGVNIICFQELWNMPFAFCTREKQPWCEFAESAEDGPTTTFLR 510 KK + ++++ A II EL N + F + + +AE+ E G T + Sbjct: 14 KKDNIERQVELVNKAIDNKAKIIALDELSNTIY-FPFEQNPKYFSWAET-ERGETLQRFK 71 Query: 511 ELAIRYAMVIVSSILERDEKHSDILWNTAVVISDTGNVIGKHRKNHIPRVGDFNESNYYM 690 E++ + ++ I ERD S+ +NTA ++ D G +IGK+RK H+P+ FNE Y+ Sbjct: 72 EISKEREVSLIVPIFERD---SNFFYNTAFIL-DNGEIIGKYRKTHLPQEEFFNEYYYFK 127 Query: 691 EGNTGHPVFAXRYGKIAVXICFGR 762 G+ G P+F + K V IC R Sbjct: 128 VGDLGFPIFDLKGVKTGVVICHDR 151 >UniRef50_Q8VYF5 Cluster: N-carbamoylputrescine amidase; n=60; cellular organisms|Rep: N-carbamoylputrescine amidase - Arabidopsis thaliana (Mouse-ear cress) Length = 326 Score = 70.1 bits (164), Expect = 7e-11 Identities = 42/133 (31%), Positives = 72/133 (54%), Gaps = 1/133 (0%) Frame = +1 Query: 361 IIDVAGQEGVNIICFQELWNMPFAFCTREKQPWCEFAESAEDGPTTTFLRELAIRYAMVI 540 ++ A +G NII QEL+ + FC +++ + + A+ ++ PT +++LA +VI Sbjct: 60 LVREAHAKGANIILIQELFE-GYYFCQAQREDFFKRAKPYKNHPTIARMQKLAKELGVVI 118 Query: 541 -VSSILERDEKHSDILWNTAVVISDTGNVIGKHRKNHIPRVGDFNESNYYMEGNTGHPVF 717 VS E + H +N+ +I G +G +RK+HIP + E Y+ G+TG VF Sbjct: 119 PVSFFEEANTAH----YNSIAIIDADGTDLGIYRKSHIPDGPGYQEKFYFNPGDTGFKVF 174 Query: 718 AXRYGKIAVXICF 756 ++ KI V IC+ Sbjct: 175 QTKFAKIGVAICW 187 >UniRef50_Q89413 Cluster: A78R protein; n=6; Chlorovirus|Rep: A78R protein - Paramecium bursaria Chlorella virus 1 (PBCV-1) Length = 298 Score = 69.7 bits (163), Expect = 9e-11 Identities = 36/136 (26%), Positives = 67/136 (49%) Frame = +1 Query: 349 KVKKIIDVAGQEGVNIICFQELWNMPFAFCTREKQPWCEFAESAEDGPTTTFLRELAIRY 528 + + ++ A G +I QEL+ + FC + + +FA+ A+D +LA Sbjct: 24 RAEMLVRNAAANGAQVIVLQELFATKY-FCQTQSPQYFKFADPADDSVIVEIFSKLAKEL 82 Query: 529 AMVIVSSILERDEKHSDILWNTAVVISDTGNVIGKHRKNHIPRVGDFNESNYYMEGNTGH 708 +VI E+D + +N+ V G+++G +RK HIP+ + E Y+ + + Sbjct: 83 GVVIPIPFFEKDGNN---YYNSVAVADADGSIVGVYRKTHIPQSKCYEEKFYFTPSSNPY 139 Query: 709 PVFAXRYGKIAVXICF 756 VF ++GK+ V IC+ Sbjct: 140 EVFETKFGKMGVLICW 155 >UniRef50_A5C5V4 Cluster: Putative uncharacterized protein; n=1; Vitis vinifera|Rep: Putative uncharacterized protein - Vitis vinifera (Grape) Length = 317 Score = 69.3 bits (162), Expect = 1e-10 Identities = 46/163 (28%), Positives = 83/163 (50%) Frame = +1 Query: 262 RIVKVGIIQHSIAVPTDRPVNEQKKAIFNKVKKIIDVAGQEGVNIICFQELWNMPFAFCT 441 R+V V +Q A D P N N ++++ A ++G NII QEL+ + FC Sbjct: 5 RVVVVSALQ--FACTDDVPTN------LNTAERLVRDAHRKGANIILIQELFE-GYYFCQ 55 Query: 442 REKQPWCEFAESAEDGPTTTFLRELAIRYAMVIVSSILERDEKHSDILWNTAVVISDTGN 621 +++ + + A+ + PT +++LA +VI S E + ++ +N+ ++ G Sbjct: 56 AQREDFFQRAKPYKGHPTILRMQKLAKELGVVIPVSFFE---EANNAHYNSIAIVDADGT 112 Query: 622 VIGKHRKNHIPRVGDFNESNYYMEGNTGHPVFAXRYGKIAVXI 750 +G +RK+HIP + E Y+ G+TG VF ++ KI V + Sbjct: 113 DLGIYRKSHIPDGPGYQEKFYFNPGDTGFKVFETKFAKIGVGL 155 >UniRef50_A7I2D9 Cluster: Hydrolase, carbon-nitrogen family; n=1; Campylobacter hominis ATCC BAA-381|Rep: Hydrolase, carbon-nitrogen family - Campylobacter hominis (strain ATCC BAA-381 / LMG 19568 / NCTC 13146 /CH001A) Length = 336 Score = 68.9 bits (161), Expect = 2e-10 Identities = 41/155 (26%), Positives = 77/155 (49%) Frame = +1 Query: 349 KVKKIIDVAGQEGVNIICFQELWNMPFAFCTREKQPWCEFAESAEDGPTTTFLRELAIRY 528 K ++I+ ++G ++ QEL + FC E+ AE+ + + F E A ++ Sbjct: 23 KSVEMIEKVAKDGAKLVILQELHEWAY-FCQSERVENFALAENFNE--SLKFWGETAKKF 79 Query: 529 AMVIVSSILERDEKHSDILWNTAVVISDTGNVIGKHRKNHIPRVGDFNESNYYMEGNTGH 708 +V+V+S+ E+ + + NTA+V + G + GK+RK HIP +F E Y+ G+ G Sbjct: 80 GIVLVTSLFEK--RAPGLFHNTAIVFENNGEIAGKYRKMHIPDDPNFYEKFYFTPGDLGF 137 Query: 709 PVFAXRYGKIAVXICFGRDHVLNWMMFGXNGXEIV 813 G++ V +C+ + + + G EI+ Sbjct: 138 EPINTSVGRLGVLVCWDQWYPEAARLMALKGAEIL 172 >UniRef50_Q7M8G2 Cluster: HYDROLASE-Predicted amidohydrolase; n=5; Bacteria|Rep: HYDROLASE-Predicted amidohydrolase - Wolinella succinogenes Length = 290 Score = 67.3 bits (157), Expect = 5e-10 Identities = 40/142 (28%), Positives = 70/142 (49%) Frame = +1 Query: 331 KKAIFNKVKKIIDVAGQEGVNIICFQELWNMPFAFCTREKQPWCEFAESAEDGPTTTFLR 510 ++A + +++I A + G ++ QEL + FC E+ + ++A E+ Sbjct: 14 REATIQRSRELILEASKGGAELVVMQELHTSEY-FCQSEETRFFDYASFYEED--VRIFS 70 Query: 511 ELAIRYAMVIVSSILERDEKHSDILWNTAVVISDTGNVIGKHRKNHIPRVGDFNESNYYM 690 +A +V+V S ER + + I NTAVV G++ G++RK HIP F E Y+ Sbjct: 71 SIAKEGGVVLVGSFFER--RSAGIYHNTAVVFEKDGSIAGRYRKMHIPDDPGFYEKFYFT 128 Query: 691 EGNTGHPVFAXRYGKIAVXICF 756 G+ G + GK+ V +C+ Sbjct: 129 PGDLGFEPISCSLGKLGVLVCW 150 >UniRef50_A6QC56 Cluster: Hydrolase; n=2; Bacteria|Rep: Hydrolase - Sulfurovum sp. (strain NBC37-1) Length = 290 Score = 66.5 bits (155), Expect = 8e-10 Identities = 40/131 (30%), Positives = 65/131 (49%) Frame = +1 Query: 364 IDVAGQEGVNIICFQELWNMPFAFCTREKQPWCEFAESAEDGPTTTFLRELAIRYAMVIV 543 I+ A +I QEL + FC E + ++A A+ +F +A ++ +V+V Sbjct: 25 IEEAASNSTELIVLQELHQNEY-FCQSEDTAFFDYA--ADFDADVSFWGAVAKKHGIVLV 81 Query: 544 SSILERDEKHSDILWNTAVVISDTGNVIGKHRKNHIPRVGDFNESNYYMEGNTGHPVFAX 723 +S+ E+ + + NTAVV GN+ GK+RK HIP F E Y+ G+ G Sbjct: 82 TSLFEK--RAPGLYHNTAVVFEKDGNIAGKYRKMHIPDDPGFYEKFYFTPGDLGFEPIET 139 Query: 724 RYGKIAVXICF 756 GK+ V +C+ Sbjct: 140 SVGKLGVLVCW 150 >UniRef50_Q606Z9 Cluster: Hydrolase, carbon-nitrogen family; n=38; Bacteria|Rep: Hydrolase, carbon-nitrogen family - Methylococcus capsulatus Length = 295 Score = 66.1 bits (154), Expect = 1e-09 Identities = 40/125 (32%), Positives = 65/125 (52%) Frame = +1 Query: 382 EGVNIICFQELWNMPFAFCTREKQPWCEFAESAEDGPTTTFLRELAIRYAMVIVSSILER 561 +G +++ EL P+ FC E + AE+ GPTT L +A +V+V+S+ ER Sbjct: 35 KGADLVMLPELHLGPY-FCQTEDCSCFDGAETIP-GPTTAELGSVARELGVVVVASLFER 92 Query: 562 DEKHSDILWNTAVVISDTGNVIGKHRKNHIPRVGDFNESNYYMEGNTGHPVFAXRYGKIA 741 + + NTAVV+ G++ GK+RK HIP + E Y+ G+ G G++ Sbjct: 93 --RAPGLYHNTAVVLDSDGSLAGKYRKMHIPDDPGYYEKFYFTPGDLGFRPIDTSVGRLG 150 Query: 742 VXICF 756 V +C+ Sbjct: 151 VLVCW 155 >UniRef50_A6BCC3 Cluster: Carbon-nitrogen hydrolase family protein; n=1; Vibrio parahaemolyticus AQ3810|Rep: Carbon-nitrogen hydrolase family protein - Vibrio parahaemolyticus AQ3810 Length = 167 Score = 64.5 bits (150), Expect = 3e-09 Identities = 36/117 (30%), Positives = 60/117 (51%) Frame = +1 Query: 406 QELWNMPFAFCTREKQPWCEFAESAEDGPTTTFLRELAIRYAMVIVSSILERDEKHSDIL 585 QEL+ P+ FC +++ + E AE + + LA +VI S E K + Sbjct: 40 QELFAAPY-FCKKQEAKYFELAEETANSHLIQEMSALAKELGVVIPVSYFE---KAGNTF 95 Query: 586 WNTAVVISDTGNVIGKHRKNHIPRVGDFNESNYYMEGNTGHPVFAXRYGKIAVXICF 756 +N+ V+I G V+ +RK+HIP ++E Y+ G+TG V+ ++GK IC+ Sbjct: 96 FNSLVMIDADGTVLDNYRKSHIPDGPGYSEKYYFSPGDTGFKVWQTKFGKFGAGICW 152 >UniRef50_O59829 Cluster: Nitrilase; n=2; cellular organisms|Rep: Nitrilase - Schizosaccharomyces pombe (Fission yeast) Length = 272 Score = 64.1 bits (149), Expect = 4e-09 Identities = 36/122 (29%), Positives = 66/122 (54%) Frame = +1 Query: 391 NIICFQELWNMPFAFCTREKQPWCEFAESAEDGPTTTFLRELAIRYAMVIVSSILERDEK 570 N+I F EL + C + + AE A +GP+ + LA +Y + I+ E++EK Sbjct: 39 NLILFPELITSGYE-CGNT---FTQIAEIAGEGPSFKTMSNLAAKYHVNIIYGFPEKEEK 94 Query: 571 HSDILWNTAVVISDTGNVIGKHRKNHIPRVGDFNESNYYMEGNTGHPVFAXRYGKIAVXI 750 S+I++N+ + I++ GN+ G +RK H+ F+ + + + P+F +GK+ V I Sbjct: 95 QSNIIYNSCIYITENGNLGGVYRKVHL-----FDTERKHFKKGSDFPIFETSFGKLGVMI 149 Query: 751 CF 756 C+ Sbjct: 150 CW 151 >UniRef50_Q54JM9 Cluster: Putative uncharacterized protein; n=1; Dictyostelium discoideum AX4|Rep: Putative uncharacterized protein - Dictyostelium discoideum AX4 Length = 328 Score = 63.3 bits (147), Expect = 8e-09 Identities = 46/150 (30%), Positives = 74/150 (49%), Gaps = 5/150 (3%) Frame = +1 Query: 322 NEQKKAIFNKVKKIIDVAGQEGVNIICFQELWNMPFAFCTREKQPWCEFAESAEDGPTTT 501 + +++ + N +K I D A + G +I E +N P++ T EK ++E+ EDG T Sbjct: 64 DNKEENVQNAIKHI-DEAAKNGAKLISLPECFNSPYSTSTFEK-----YSET-EDGETVK 116 Query: 502 FLRELAIRYAMVIVSSILERDEKHSDILWNTAVVISDTGNVIGKHRKNH-----IPRVGD 666 L E A R + +V + +K + ++NT + +D G V+ KHRK H +P Sbjct: 117 KLSEAAKRNQIFLVGGSIPEIDKATGKIYNTCFIFNDKGEVVKKHRKIHLFDIDVPNKIR 176 Query: 667 FNESNYYMEGNTGHPVFAXRYGKIAVXICF 756 F ES G++ V Y KI V IC+ Sbjct: 177 FKESETLTPGDS-FSVVDIGYCKIGVAICY 205 >UniRef50_A0QWL8 Cluster: Carbon-nitrogen hydrolase family protein; n=6; Bacteria|Rep: Carbon-nitrogen hydrolase family protein - Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155) Length = 299 Score = 61.3 bits (142), Expect = 3e-08 Identities = 51/176 (28%), Positives = 87/176 (49%), Gaps = 1/176 (0%) Frame = +1 Query: 232 PAKDEQTRPPRIVKVGIIQHSIAVPTDRPVNEQKKAIFNKVKKIIDVAGQEGVNIICFQE 411 P +D P +V ++Q + V + + +A++ ++++ VAG G N+I E Sbjct: 2 PDQDSHRFSP--ARVAVVQFNPQVGVEN-LKANSEAVYERLQQA--VAG--GANLIVLPE 54 Query: 412 LWNMPFAFCTREKQPWCEFAESAEDGPTTTFLRELAIRYAMVIVSSILERDEKHSDILWN 591 L + F +RE+ AE G T T E A + + IV + E D L++ Sbjct: 55 LATTGYTFESREEA--YAHAEPVPSGATVTGWAEFAAAHDVYIVGCLPELDGVE---LFD 109 Query: 592 TAVVISDTGNVIGKHRKNHIPRVGDFNESN-YYMEGNTGHPVFAXRYGKIAVXICF 756 TAV++ G IGK+RK H+ +NE ++ G+ G+PVF R G+I + +C+ Sbjct: 110 TAVLVGPEG-YIGKYRKTHL-----WNEEKLFFSPGDLGYPVFHTRIGRIGLLVCW 159 >UniRef50_A6CCK5 Cluster: Putative uncharacterized protein; n=1; Planctomyces maris DSM 8797|Rep: Putative uncharacterized protein - Planctomyces maris DSM 8797 Length = 450 Score = 60.9 bits (141), Expect = 4e-08 Identities = 52/175 (29%), Positives = 87/175 (49%), Gaps = 2/175 (1%) Frame = +1 Query: 238 KDEQTRPPRIVKVGIIQHSIAVPTDRPVNEQKKAIFNKVKKIIDVAGQEGVNIICFQELW 417 K + PRIV++ I H P K A F K+I+ A ++ +++ E Sbjct: 187 KQTKDLQPRIVRLATIHHR---PQAGKKPSDKPAQF---AKLIEQAAEQKADLVVLPESI 240 Query: 418 NMPFAFCTREKQPWCEFAESAED--GPTTTFLRELAIRYAMVIVSSILERDEKHSDILWN 591 + + T +AE+AE GP+T + ELA ++ + IV + ER + +++N Sbjct: 241 TV---YGTG-----LSYAETAEPIPGPSTQYFGELAKKHDLYIVVGLYERA---AHLVYN 289 Query: 592 TAVVISDTGNVIGKHRKNHIPRVGDFNESNYYMEGNTGHPVFAXRYGKIAVXICF 756 AV+I G V+GK+RK +PR G+ GN +PVF R+GK+ + +C+ Sbjct: 290 VAVLIGPDGKVVGKYRKVTLPR-GEIEGG--VTPGNE-YPVFETRFGKVGMMVCY 340 >UniRef50_A0TTW8 Cluster: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; n=5; Proteobacteria|Rep: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase - Burkholderia cenocepacia MC0-3 Length = 299 Score = 60.1 bits (139), Expect = 7e-08 Identities = 44/131 (33%), Positives = 66/131 (50%) Frame = +1 Query: 364 IDVAGQEGVNIICFQELWNMPFAFCTREKQPWCEFAESAEDGPTTTFLRELAIRYAMVIV 543 I+ A + G +I EL + + F R++ AE DGPT +A R + IV Sbjct: 42 IETAARNGAALIVLPELASSGYVFEDRDEA--LALAELVPDGPTARAFEAIARRLNVHIV 99 Query: 544 SSILERDEKHSDILWNTAVVISDTGNVIGKHRKNHIPRVGDFNESNYYMEGNTGHPVFAX 723 S I ERD L+N+A+ G+ +G +RK H+ D NE ++ G+ G PVF Sbjct: 100 SGIAERDGAR---LYNSALFAGPGGH-LGVYRKLHL---WD-NEKRFFEPGDRGVPVFDT 151 Query: 724 RYGKIAVXICF 756 G+IA+ IC+ Sbjct: 152 PLGRIAMAICY 162 >UniRef50_Q8RUF8 Cluster: AT5g12040/F14F18_210; n=9; Magnoliophyta|Rep: AT5g12040/F14F18_210 - Arabidopsis thaliana (Mouse-ear cress) Length = 369 Score = 60.1 bits (139), Expect = 7e-08 Identities = 44/153 (28%), Positives = 69/153 (45%), Gaps = 7/153 (4%) Frame = +1 Query: 319 VNEQKKAIFNKVKKIIDVAGQEGVNIICFQELWNMPFAFCTREKQP-WCEFAESAED-GP 492 V KK + KK I+ A +G ++ E+WN P+ + + P + E ++ D P Sbjct: 97 VTSDKKRNISHAKKAIEEAASKGAKLVLLPEIWNSPY---SNDSFPVYAEEIDAGGDASP 153 Query: 493 TTTFLRELAIRYAMVIVSSILERDEKHSDILWNTAVVISDTGNVIGKHRKNH-----IPR 657 +T L E++ R + I+ + E+ D L+NT V G + KHRK H IP Sbjct: 154 STAMLSEVSKRLKITIIGGSI--PERVGDRLYNTCCVFGSDGELKAKHRKIHLFDIDIPG 211 Query: 658 VGDFNESNYYMEGNTGHPVFAXRYGKIAVXICF 756 F ES G T + G+I + IC+ Sbjct: 212 KITFMESKTLTAGET-PTIVDTDVGRIGIGICY 243 >UniRef50_A6DDT2 Cluster: HYDROLASE-Predicted amidohydrolase; n=1; Caminibacter mediatlanticus TB-2|Rep: HYDROLASE-Predicted amidohydrolase - Caminibacter mediatlanticus TB-2 Length = 299 Score = 59.7 bits (138), Expect = 1e-07 Identities = 46/162 (28%), Positives = 80/162 (49%) Frame = +1 Query: 328 QKKAIFNKVKKIIDVAGQEGVNIICFQELWNMPFAFCTREKQPWCEFAESAEDGPTTTFL 507 ++K I + +K I G+ ++ QEL + FC E + ++AES + F Sbjct: 14 KEKTISHTIKMINKSNGE----LVILQELHQNEY-FCKCENTKYFDYAESFNED--VEFW 66 Query: 508 RELAIRYAMVIVSSILERDEKHSDILWNTAVVISDTGNVIGKHRKNHIPRVGDFNESNYY 687 R ++ +V+V+S+ E+ I +NTAVV D G + GK+RK HIP F E Y+ Sbjct: 67 RRVSEDKNIVLVTSLFEK--VMDGIYYNTAVVF-DKGKIAGKYRKTHIPDDPGFYEKFYF 123 Query: 688 MEGNTGHPVFAXRYGKIAVXICFGRDHVLNWMMFGXNGXEIV 813 + G+ P+ G++ V +C+ + + + G EI+ Sbjct: 124 IPGDEIEPI-DTSIGRLGVLVCWDQWYPEPARIMALKGAEIL 164 >UniRef50_A3H7D3 Cluster: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; n=1; Caldivirga maquilingensis IC-167|Rep: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase - Caldivirga maquilingensis IC-167 Length = 279 Score = 59.7 bits (138), Expect = 1e-07 Identities = 32/91 (35%), Positives = 51/91 (56%) Frame = +1 Query: 484 DGPTTTFLRELAIRYAMVIVSSILERDEKHSDILWNTAVVISDTGNVIGKHRKNHIPRVG 663 DG + L E+A I++ I ERD K + +++N+AV I + G ++ +RK H+P G Sbjct: 63 DGKSIGELTEIAREGKCTIITGIAERD-KDTGVVYNSAVAIGENG-LMALYRKRHLPSYG 120 Query: 664 DFNESNYYMEGNTGHPVFAXRYGKIAVXICF 756 F+ES Y+ G PVF+ K + IC+ Sbjct: 121 VFDESRYFGVGRGDAPVFSMNGTKAGLAICY 151 >UniRef50_Q44185 Cluster: N-carbamoyl-D-amino acid hydrolase; n=10; Proteobacteria|Rep: N-carbamoyl-D-amino acid hydrolase - Agrobacterium tumefaciens Length = 304 Score = 59.3 bits (137), Expect = 1e-07 Identities = 48/192 (25%), Positives = 84/192 (43%), Gaps = 16/192 (8%) Frame = +1 Query: 286 QHSIAVPTDRPVN--EQKKAIFNKVKKIIDVAGQEGVNIICFQELWNMPF--AFCTREKQ 453 Q +AV P+ E ++ + ++ ++ A GVN I F EL F + ++ Sbjct: 4 QMILAVGQQGPIARAETREQVVGRLLDMLTNAASRGVNFIVFPELALTTFFPRWHFTDEA 63 Query: 454 PWCEFAESAEDGPTTTFL----RELAIRYAMVIVSSILERDEKHSDILWNTAVVISDTGN 621 F E+ GP L EL I + + ++E K +NT++++ +G Sbjct: 64 ELDSFYETEMPGPVVRPLFETAAELGIGFNLGYAELVVEGGVKRR---FNTSILVDKSGK 120 Query: 622 VIGKHRKNHIPRVGDFN--------ESNYYMEGNTGHPVFAXRYGKIAVXICFGRDHVLN 777 ++GK+RK H+P ++ E Y+ G+ G PV+ K+ + IC R Sbjct: 121 IVGKYRKIHLPGHKEYEAYRPFQHLEKRYFEPGDLGFPVYDVDAAKMGMFICNDRRWPET 180 Query: 778 WMMFGXNGXEIV 813 W + G G EI+ Sbjct: 181 WRVMGLKGAEII 192 >UniRef50_A3LZY2 Cluster: Aliphatic nitrilase; n=1; Pichia stipitis|Rep: Aliphatic nitrilase - Pichia stipitis (Yeast) Length = 323 Score = 57.2 bits (132), Expect = 5e-07 Identities = 44/154 (28%), Positives = 68/154 (44%), Gaps = 8/154 (5%) Frame = +1 Query: 316 PVNEQKKAIFNKVKKIIDVAGQEGVNIICFQELWNMPFAFCTREKQP------WCEFAES 477 PV K+A KV + A +G N+I F E + F K P + + ES Sbjct: 15 PVMMNKEATMEKVFNGVSEAASKGANLIVFPETYVSAFPLWGACKAPIDNHHLFKQLVES 74 Query: 478 AE--DGPTTTFLRELAIRYAMVIVSSILERDEKHSDILWNTAVVISDTGNVIGKHRKNHI 651 + DGP + L+ L ++V++ ER LWN+ V+I + G IG H + + Sbjct: 75 SIYIDGPEISSLQSLCKELSVVVLLGFNERSRVSVGCLWNSYVLIDENG-TIGAHHRKLV 133 Query: 652 PRVGDFNESNYYMEGNTGHPVFAXRYGKIAVXIC 753 P F + ++ +G V +YGKI IC Sbjct: 134 PTF--FEKLSWANGDGSGLNVIDSKYGKIGCLIC 165 >UniRef50_Q2AH52 Cluster: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; n=1; Halothermothrix orenii H 168|Rep: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase - Halothermothrix orenii H 168 Length = 273 Score = 56.4 bits (130), Expect = 9e-07 Identities = 35/111 (31%), Positives = 52/111 (46%) Frame = +1 Query: 487 GPTTTFLRELAIRYAMVIVSSILERDEKHSDILWNTAVVISDTGNVIGKHRKNHIPRVGD 666 G TT E A Y I+ +++ERD+ +IL+NT VI G+ GK+RK H+ Sbjct: 67 GRTTEIFSEYARMYKTAIIGNMVERDKNVGEILYNTTFVIDKKGDYTGKYRKVHVYPA-- 124 Query: 667 FNESNYYMEGNTGHPVFAXRYGKIAVXICFGRDHVLNWMMFGXNGXEIVXI 819 E Y+ G T PVF KI + C+ + + G +I+ I Sbjct: 125 --EFTYFKRG-TEFPVFNVNGVKIGLATCYDHGFGEMFRILARKGAQIIFI 172 >UniRef50_A7GE66 Cluster: Hydrolase, carbon-nitrogen family; n=13; cellular organisms|Rep: Hydrolase, carbon-nitrogen family - Clostridium botulinum (strain Langeland / NCTC 10281 / Type F) Length = 278 Score = 56.4 bits (130), Expect = 9e-07 Identities = 41/151 (27%), Positives = 72/151 (47%), Gaps = 5/151 (3%) Frame = +1 Query: 319 VNEQKKAIFNKVKKIIDVAGQEGVNIICFQELWNMPFAFCTREKQPWCEFAESAEDGPTT 498 V ++KK K +++ A +E NI E++N P+ + +P+ E G T Sbjct: 13 VQKEKKKNIKKAIEMLTKAKKENCNIAVLPEMFNCPYE--NKCFKPYGEIINEENGGETV 70 Query: 499 TFLRELAIRYAMVIVSSILERDEKHSDILWNTAVVISDTGNVIGKHRKNHIPRVG----- 663 +++ A + IV+ + E D ++NT++V + G +I KHRK H+ + Sbjct: 71 KAIKKAAKDLELYIVAGSIPEIE--GDKIYNTSMVFDNKGVLIAKHRKVHLFDIDVKGGV 128 Query: 664 DFNESNYYMEGNTGHPVFAXRYGKIAVXICF 756 F ES+ GN +F +GK+ V IC+ Sbjct: 129 TFKESDTLTAGNK-ITLFNTPWGKLGVMICY 158 >UniRef50_Q5KJU9 Cluster: Hydrolase, putative; n=1; Filobasidiella neoformans|Rep: Hydrolase, putative - Cryptococcus neoformans (Filobasidiella neoformans) Length = 301 Score = 56.4 bits (130), Expect = 9e-07 Identities = 46/136 (33%), Positives = 65/136 (47%), Gaps = 15/136 (11%) Frame = +1 Query: 394 IICFQELWNMPFAFCT----REKQP-----WCEFAESAEDGPTTTFLRELA-IRYAMVIV 543 +I E+WN P+A + EK P W E E+G T LRE+A +I Sbjct: 46 LIVLPEIWNSPYAVSSFREYSEKVPEVGSKWKSLKEG-EEGETIKALREMARSSGCWLIG 104 Query: 544 SSILERDEKHSDILWNTAVVISDTGNVIGKHRKNH-----IPRVGDFNESNYYMEGNTGH 708 SI ERDEK +D ++NT V G ++ H+K H IP F ES+ + G + Sbjct: 105 GSIPERDEK-TDNIYNTCTVYDPEGTLVAVHQKVHLFDIDIPGKQTFKESD-TLTGGSHL 162 Query: 709 PVFAXRYGKIAVXICF 756 F +GKI + IC+ Sbjct: 163 TTFTTPFGKIGLGICY 178 >UniRef50_Q6N746 Cluster: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; n=11; Proteobacteria|Rep: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase - Rhodopseudomonas palustris Length = 579 Score = 54.4 bits (125), Expect = 4e-06 Identities = 46/173 (26%), Positives = 78/173 (45%) Frame = +1 Query: 295 IAVPTDRPVNEQKKAIFNKVKKIIDVAGQEGVNIICFQELWNMPFAFCTREKQPWCEFAE 474 +A P+ +K+ ++ ++ + A G +I E+ +C ++ F E Sbjct: 7 VATVQFEPIMAEKERNIARLLELCEEAAVGGAKLIVTPEMGTT--GYCWYDRAEVAPFVE 64 Query: 475 SAEDGPTTTFLRELAIRYAMVIVSSILERDEKHSDILWNTAVVISDTGNVIGKHRKNHIP 654 G TT ELA ++ IV + E DE I +N+AV+I G +IG+HRK H P Sbjct: 65 PIP-GATTARFAELARKHDCYIVVGLPEVDE--DGIYYNSAVLIGPEG-LIGRHRKTH-P 119 Query: 655 RVGDFNESNYYMEGNTGHPVFAXRYGKIAVXICFGRDHVLNWMMFGXNGXEIV 813 + +E + G+ + VF G+IA+ IC V + G +I+ Sbjct: 120 YI---SEPKWSAAGDLHNQVFDTPIGRIALLICMDIHFVETARLMALGGADII 169 Score = 37.9 bits (84), Expect = 0.33 Identities = 23/58 (39%), Positives = 33/58 (56%) Frame = +1 Query: 478 AEDGPTTTFLRELAIRYAMVIVSSILERDEKHSDILWNTAVVISDTGNVIGKHRKNHI 651 A GP T L LA ++ +V + ERD DIL+N+AV+I+ G I +RK H+ Sbjct: 346 AVPGPATDRLAALASELSLYLVCGLAERD---GDILYNSAVLIAPDG-TITTYRKTHL 399 >UniRef50_Q6N4F1 Cluster: Possible amidohydrolase; n=2; Rhodopseudomonas palustris|Rep: Possible amidohydrolase - Rhodopseudomonas palustris Length = 557 Score = 54.4 bits (125), Expect = 4e-06 Identities = 38/134 (28%), Positives = 62/134 (46%), Gaps = 1/134 (0%) Frame = +1 Query: 358 KIIDVAGQEGVNIICFQELWNMPFAFCTREKQPWC-EFAESAEDGPTTTFLRELAIRYAM 534 + ++ A ++G +I F E + + F + E C E AE+ DGP L L+ ++ + Sbjct: 29 RYVEDAARQGAELIVFPECMDTGYLFDSPEH---CRELAETLTDGPFVKALAALSRKHGV 85 Query: 535 VIVSSILERDEKHSDILWNTAVVISDTGNVIGKHRKNHIPRVGDFNESNYYMEGNTGHPV 714 I S I E D I +NT ++ G V + K + ++ N++ G G PV Sbjct: 86 YIASGITEWDPAKEKI-FNTGIMFDRKGEVACHYHKQFLAT----HDQNWFAFGERGCPV 140 Query: 715 FAXRYGKIAVXICF 756 GKI + ICF Sbjct: 141 VETDLGKIGLLICF 154 Score = 35.5 bits (78), Expect = 1.8 Identities = 23/78 (29%), Positives = 38/78 (48%) Frame = +1 Query: 511 ELAIRYAMVIVSSILERDEKHSDILWNTAVVISDTGNVIGKHRKNHIPRVGDFNESNYYM 690 +++ RY +I + I+ER L+ T V+I G IG++RK H+ E + Sbjct: 362 KISARYGCLIAAPIVERAAAG---LYVTTVLIGSDGKEIGRYRKTHLTA-----EERKWA 413 Query: 691 EGNTGHPVFAXRYGKIAV 744 +PVF +G+I V Sbjct: 414 VAGFDYPVFDTPFGRIGV 431 >UniRef50_A6TPX2 Cluster: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; n=1; Alkaliphilus metalliredigens QYMF|Rep: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase - Alkaliphilus metalliredigens QYMF Length = 269 Score = 54.4 bits (125), Expect = 4e-06 Identities = 41/166 (24%), Positives = 73/166 (43%) Frame = +1 Query: 316 PVNEQKKAIFNKVKKIIDVAGQEGVNIICFQELWNMPFAFCTREKQPWCEFAESAEDGPT 495 P+ +A + + I A + V++I ELW + K+ + + AE +DG T Sbjct: 11 PIMNDVEANLKRGQHFIQQAAAQEVDLIVLPELWTTGYYL---SKESFKQLAEH-KDGRT 66 Query: 496 TTFLRELAIRYAMVIVSSILERDEKHSDILWNTAVVISDTGNVIGKHRKNHIPRVGDFNE 675 T +++ A+R I+ +E E L+ A VI G + G K+ + E Sbjct: 67 VTLMQDQALRSNASIICPFVEITEDKK--LYIAAAVIDHRGELRGTVHKSLLWG----RE 120 Query: 676 SNYYMEGNTGHPVFAXRYGKIAVXICFGRDHVLNWMMFGXNGXEIV 813 + EGN +PVF + GK+ + IC+ + + G E++ Sbjct: 121 QQIFEEGNIEYPVFDTKIGKVGILICYEMEFPETSRLLALQGVEMI 166 >UniRef50_Q2NHR0 Cluster: Predicted amidohydrolase; n=1; Methanosphaera stadtmanae DSM 3091|Rep: Predicted amidohydrolase - Methanosphaera stadtmanae (strain DSM 3091) Length = 274 Score = 54.4 bits (125), Expect = 4e-06 Identities = 38/158 (24%), Positives = 72/158 (45%), Gaps = 4/158 (2%) Frame = +1 Query: 358 KIIDVAGQEGVNIICFQELWNMPFAFCTREKQPWCEFAESAEDGPTTTFLRELAIRYAMV 537 ++I A G +I E++N P+ + + E+ E T ++++A + Sbjct: 26 QLIKKASSNGAKLITLPEMFNTPY-----DNSKFIEYCEEETTSKTLNSMQDIAREENIY 80 Query: 538 IVSSILERDEKHSDILWNTAVVISDTGNVIGKHRKNHIPRVG----DFNESNYYMEGNTG 705 + S + EK S+ L+NTA +I+ G +IGKHRK H+ + F ES+ G++ Sbjct: 81 LQSGSIP--EKESNHLYNTAYLINPKGKIIGKHRKMHMFDIDTDNMKFTESDTLTPGDSV 138 Query: 706 HPVFAXRYGKIAVXICFGRDHVLNWMMFGXNGXEIVXI 819 + I++ IC+ W + N +I+ + Sbjct: 139 TTI-KTPLANISIAICYDIRFPELWTLMNKNNSDIILL 175 >UniRef50_Q0AX54 Cluster: N-carbamoyl-D-amino acid amidohydrolase; n=1; Syntrophomonas wolfei subsp. wolfei str. Goettingen|Rep: N-carbamoyl-D-amino acid amidohydrolase - Syntrophomonas wolfei subsp. wolfei (strain Goettingen) Length = 283 Score = 53.6 bits (123), Expect = 6e-06 Identities = 32/102 (31%), Positives = 57/102 (55%), Gaps = 1/102 (0%) Frame = +1 Query: 349 KVKKIIDVAGQEGVNIICFQELWNMPFAFCTREKQPWCEFAESAEDGPTTTFLRELAIRY 528 K ++I A EG ++ E++N P+ + + + +AE GP+T FL A ++ Sbjct: 24 KAGEMIAAAAGEGAEMVVLPEVFNSPY-----QAELFPRYAEPFP-GPSTDFLAAAACKH 77 Query: 529 AMVIVS-SILERDEKHSDILWNTAVVISDTGNVIGKHRKNHI 651 + IV SI+ERD + ++N++ V + G +IG+HRK H+ Sbjct: 78 GLCIVGGSIIERDSQGK--IYNSSFVFDERGELIGRHRKAHL 117 >UniRef50_A0QPL8 Cluster: Hydrolase, carbon-nitrogen family protein; n=6; Bacteria|Rep: Hydrolase, carbon-nitrogen family protein - Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155) Length = 330 Score = 53.6 bits (123), Expect = 6e-06 Identities = 39/148 (26%), Positives = 67/148 (45%) Frame = +1 Query: 253 RPPRIVKVGIIQHSIAVPTDRPVNEQKKAIFNKVKKIIDVAGQEGVNIICFQELWNMPFA 432 RPP ++VG++QH RP + +++ ID A EG + E+ + + Sbjct: 20 RPP--LRVGLVQHRW-----RP---DAGELVKVLREGIDRAAGEGAKAVFLPEITLLRYP 69 Query: 433 FCTREKQPWCEFAESAEDGPTTTFLRELAIRYAMVIVSSILERDEKHSDILWNTAVVISD 612 T + AE GPT E A + + +S+ E+ + +NTA+++S Sbjct: 70 ADTPAGPNPGDVAEDLTGGPTFELAAEAARANGIFVHASLYEKAPAADGLGYNTAILVSP 129 Query: 613 TGNVIGKHRKNHIPRVGDFNESNYYMEG 696 G ++G+ RK HIP + E Y+ G Sbjct: 130 EGELVGRTRKMHIPISAGYYEDTYFRPG 157 >UniRef50_A2BNC1 Cluster: Predicted amidohydrolase; n=1; Hyperthermus butylicus DSM 5456|Rep: Predicted amidohydrolase - Hyperthermus butylicus (strain DSM 5456 / JCM 9403) Length = 269 Score = 53.6 bits (123), Expect = 6e-06 Identities = 30/112 (26%), Positives = 57/112 (50%) Frame = +1 Query: 484 DGPTTTFLRELAIRYAMVIVSSILERDEKHSDILWNTAVVISDTGNVIGKHRKNHIPRVG 663 +GP F LA Y++ +V+++ E+ K +NTA +I+ TG ++ +RK H+ Sbjct: 67 EGPWIGFFARLAREYSVHVVATLYEKS-KAGGKPYNTAALIAPTGELLAVYRKIHLFDAY 125 Query: 664 DFNESNYYMEGNTGHPVFAXRYGKIAVXICFGRDHVLNWMMFGXNGXEIVXI 819 + ES+Y+M G + + +IA+ +CF + + G E+V + Sbjct: 126 GYRESDYFMPGAEPAKLATIKGFRIALAVCFDLRFPELFRTYALQGAELVAV 177 >UniRef50_A4J4S3 Cluster: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; n=1; Desulfotomaculum reducens MI-1|Rep: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase - Desulfotomaculum reducens MI-1 Length = 273 Score = 53.2 bits (122), Expect = 8e-06 Identities = 41/128 (32%), Positives = 57/128 (44%) Frame = +1 Query: 373 AGQEGVNIICFQELWNMPFAFCTREKQPWCEFAESAEDGPTTTFLRELAIRYAMVIVSSI 552 A G IIC EL + E + W E E GPTT +LA + I+ + Sbjct: 33 AAAMGAQIICLPELCTTGYRPDLLEDKLW-ELTEPVP-GPTTDVFSQLAKELGIYIILPM 90 Query: 553 LERDEKHSDILWNTAVVISDTGNVIGKHRKNHIPRVGDFNESNYYMEGNTGHPVFAXRYG 732 E+ ++ N+AV I G V G RK H E Y+ +GN +PVF +G Sbjct: 91 NEKGAVPG-MIHNSAVFIDKDGEVQGVFRKAHAYAT----ERYYFTDGNH-YPVFQTEFG 144 Query: 733 KIAVXICF 756 K+ V IC+ Sbjct: 145 KVGVMICY 152 >UniRef50_A4SZC4 Cluster: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase precursor; n=1; Polynucleobacter sp. QLW-P1DMWA-1|Rep: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase precursor - Polynucleobacter sp. QLW-P1DMWA-1 Length = 622 Score = 51.6 bits (118), Expect = 3e-05 Identities = 43/169 (25%), Positives = 78/169 (46%), Gaps = 4/169 (2%) Frame = +1 Query: 319 VNEQKKAIFNKVKKIIDV---AGQEGVNIICFQELWNMPFAFCTREKQ-PWCEFAESAED 486 V+ K + + K+ D+ A + G +I F E+ + F + T E+ P + Sbjct: 29 VSFHSKDMAYNIPKMADISADAAKNGAKLIVFPEMASTGFLYMTLEQAGPNVD----TFP 84 Query: 487 GPTTTFLRELAIRYAMVIVSSILERDEKHSDILWNTAVVISDTGNVIGKHRKNHIPRVGD 666 G T ++A +Y I +E D K + + +N+A ++ G G +RK+ + VGD Sbjct: 85 GKATAAFGQVAQKYNTYIAWGYIELDPK-TGVAYNSAAIVGPNG-FSGNYRKHQLA-VGD 141 Query: 667 FNESNYYMEGNTGHPVFAXRYGKIAVXICFGRDHVLNWMMFGXNGXEIV 813 N + GN G PVF GKIA+ +C+ + + ++ +I+ Sbjct: 142 DNL--FRAPGNIGFPVFNTPIGKIALLVCYDDSQLQSLLLPALRNADII 188 >UniRef50_A2XD42 Cluster: Putative uncharacterized protein; n=2; Oryza sativa|Rep: Putative uncharacterized protein - Oryza sativa subsp. indica (Rice) Length = 349 Score = 50.8 bits (116), Expect = 4e-05 Identities = 41/155 (26%), Positives = 66/155 (42%), Gaps = 9/155 (5%) Frame = +1 Query: 319 VNEQKKAIFNKVKKIIDVAGQEGVNIICFQELWNMPFAFCTREKQPWCEFAESAEDG--- 489 V K + ++ I+ A G ++ E+WN P++ + E+AE E G Sbjct: 55 VTADKARNIARAREAIEAAAAGGAKLVLLPEIWNGPYS-----NDSFPEYAEDIEAGGDA 109 Query: 490 -PTTTFLRELAIRYAMVIVSSILERDEKHSDILWNTAVVISDTGNVIGKHRKNH-----I 651 P+ + + E+A + +V + E+ + L+NT V G + GKHRK H I Sbjct: 110 APSFSMMSEVARSLQITLVGGSIS--ERSGNKLYNTCCVFGSDGELKGKHRKIHLFDIDI 167 Query: 652 PRVGDFNESNYYMEGNTGHPVFAXRYGKIAVXICF 756 P F ES G V G+I + IC+ Sbjct: 168 PGKITFKESKTLTAGQ-DLTVVDTDVGRIGIGICY 201 >UniRef50_Q9KE11 Cluster: BH1047 protein; n=1; Bacillus halodurans|Rep: BH1047 protein - Bacillus halodurans Length = 271 Score = 48.4 bits (110), Expect = 2e-04 Identities = 54/186 (29%), Positives = 84/186 (45%), Gaps = 2/186 (1%) Frame = +1 Query: 268 VKVGIIQHSIAVPTDRPVNEQKKAIFNKVKKII-DVAGQEGV-NIICFQELWNMPFAFCT 441 +KV + Q I +P D NE+K VK+ I DV QE V +++ E+W + Sbjct: 1 MKVALYQMDI-LPGDPRGNERK------VKEWIEDVMQQEDVPDLLVLPEMWTTAYTLDQ 53 Query: 442 REKQPWCEFAESAEDGPTTTFLRELAIRYAMVIVSSILERDEKHSDILWNTAVVISDTGN 621 E AE E+ T FL+ELA + + IV+ + + EK L+N A+V G+ Sbjct: 54 LE-----HLAEG-EERYTELFLKELAREHNVNIVAGSIAKKEKGK--LYNRALVFDRRGH 105 Query: 622 VIGKHRKNHIPRVGDFNESNYYMEGNTGHPVFAXRYGKIAVXICFGRDHVLNWMMFGXNG 801 + ++ K H+ V +E +Y G+ VF K+ + IC+ G Sbjct: 106 TVYQYDKIHL--VPMLSEPDYLTGGDAAASVFELEGTKMGLVICYDLRFPELMRSLALEG 163 Query: 802 XEIVXI 819 EIV I Sbjct: 164 AEIVFI 169 >UniRef50_A4M5M1 Cluster: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; n=1; Petrotoga mobilis SJ95|Rep: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase - Petrotoga mobilis SJ95 Length = 276 Score = 48.4 bits (110), Expect = 2e-04 Identities = 30/117 (25%), Positives = 59/117 (50%) Frame = +1 Query: 469 AESAEDGPTTTFLRELAIRYAMVIVSSILERDEKHSDILWNTAVVISDTGNVIGKHRKNH 648 AE DG TT + +A +Y + IV++ILE+D ++T+++I ++G ++GK+RK Sbjct: 61 AEIIPDGETTQEVVRIAKKYNISIVANILEKDPLIIGKYYDTSILIDESGKLLGKYRKIF 120 Query: 649 IPRVGDFNESNYYMEGNTGHPVFAXRYGKIAVXICFGRDHVLNWMMFGXNGXEIVXI 819 + F + + + T + + KI + IC+ + + G +I+ I Sbjct: 121 V-----FPKEKFRLSEGTSIEIIDWKGIKIGLSICYDHAFPELYRIMALRGAQILII 172 >UniRef50_A6CFF3 Cluster: Putative nitrilase; n=1; Planctomyces maris DSM 8797|Rep: Putative nitrilase - Planctomyces maris DSM 8797 Length = 343 Score = 48.0 bits (109), Expect = 3e-04 Identities = 43/155 (27%), Positives = 62/155 (40%), Gaps = 9/155 (5%) Frame = +1 Query: 316 PVNEQKKAIFNKVKKIIDVAGQEGVNIICFQELWNMPFAFCTREKQP------WCEFAES 477 PV K A K +I A + G +I F E + F + P +CE A + Sbjct: 15 PVFLNKDATVEKSCSLIREAARNGAQMIVFPETYIPAFPVWCALQAPIHNHDLFCELAAN 74 Query: 478 A--EDGPTTTFLRELAIRYAMVIVSSILERDEKHSDILWNTAVVISDTGNVIGKHRKNHI 651 + DGP + E A M + E +WN +I D GN++ HRK Sbjct: 75 SIKVDGPELAQIAETARECEMFVSMGFNEGTTVSDGCIWNANALIGDDGNILCHHRK--- 131 Query: 652 PRVGDFNESNYYMEGN-TGHPVFAXRYGKIAVXIC 753 V F E + G+ G V A R G++ + IC Sbjct: 132 -IVPTFYEKLVWSPGDGAGLEVCATRLGRLGMLIC 165 >UniRef50_Q84FR7 Cluster: D-N-carbamoylase; n=1; Arthrobacter crystallopoietes|Rep: D-N-carbamoylase - Arthrobacter crystallopoietes Length = 315 Score = 46.8 bits (106), Expect = 7e-04 Identities = 39/177 (22%), Positives = 78/177 (44%), Gaps = 11/177 (6%) Frame = +1 Query: 322 NEQKKAIFNKVKKIIDVAGQEGVNIICFQELWNMPFAFCTR-EKQPWCEFAESA--EDGP 492 +E + + ++ +++ A +G ++ F EL F T E+ + E+ + + D Sbjct: 18 SESRPEVVARLIALLEEAASQGAELVVFPELTLTTFFPRTWFEEGDFEEYFDKSMPNDDV 77 Query: 493 TTTFLRELAIRYAMVIVSSILERDEKHSDILWNTAVVISDTGNVIGKHRKNHIPRVGDFN 672 F R + + + L DEK +NT+++++ G+++GK+RK H+P D Sbjct: 78 APLFERAKDLGVGFYLGYAELTSDEKR----YNTSILVNKHGDIVGKYRKMHLPGHADNR 133 Query: 673 --------ESNYYMEGNTGHPVFAXRYGKIAVXICFGRDHVLNWMMFGXNGXEIVXI 819 E Y+ EG+ G VF ++ + +C R + G E+V + Sbjct: 134 EGLPNQHLEKKYFREGDLGFGVFDFHGVQVGMCLCNDRRWPEVYRSLALQGAELVVL 190 >UniRef50_A7DPX6 Cluster: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; n=2; Crenarchaeota|Rep: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase - Candidatus Nitrosopumilus maritimus SCM1 Length = 268 Score = 45.6 bits (103), Expect = 0.002 Identities = 37/144 (25%), Positives = 59/144 (40%), Gaps = 2/144 (1%) Frame = +1 Query: 331 KKAIFNKVKKIIDVAGQEGVNIICFQELWNMPFAFCTREKQPWCEFAESAE--DGPTTTF 504 K+ K+ I+ A + + F E F T Q + A AE +G Sbjct: 14 KETNLKKIISFIEKAASKNATLCAFPEF----MMFYTNSSQTPKQLATLAETINGNFVNT 69 Query: 505 LRELAIRYAMVIVSSILERDEKHSDILWNTAVVISDTGNVIGKHRKNHIPRVGDFNESNY 684 + A + +V S E+ K D +++T+ VI TG VI +RK H+ F ES+ Sbjct: 70 IANTAKENHVQVVGSFYEKSRK-KDRVYDTSFVIDKTGKVISTYRKIHLYDALGFRESDK 128 Query: 685 YMEGNTGHPVFAXRYGKIAVXICF 756 G+ GK+ + IC+ Sbjct: 129 MASGSKIAKPVKTTIGKVGMMICY 152 >UniRef50_A0RYH6 Cluster: Amidohydrolase; n=1; Cenarchaeum symbiosum|Rep: Amidohydrolase - Cenarchaeum symbiosum Length = 269 Score = 45.6 bits (103), Expect = 0.002 Identities = 33/138 (23%), Positives = 60/138 (43%), Gaps = 2/138 (1%) Frame = +1 Query: 349 KVKKIIDVAGQEGVNIICFQELWNMPFAFCTREKQPWCEFAESAE--DGPTTTFLRELAI 522 ++ K + A G ++ F E F T Q E A AE DGP + + A Sbjct: 21 RIVKYVSEAAAGGAGLVAFPEF----MMFYTPPGQTPAELARLAENIDGPFVKSVADAAR 76 Query: 523 RYAMVIVSSILERDEKHSDILWNTAVVISDTGNVIGKHRKNHIPRVGDFNESNYYMEGNT 702 Y++ +V +I ER + + ++T+ ++ G+++ +RK H+ F ES G+ Sbjct: 77 DYSIEVVGTIYERSPRRGRV-YDTSFLLGRDGSLLSSYRKIHLYDALGFKESAKLAPGDR 135 Query: 703 GHPVFAXRYGKIAVXICF 756 G + + IC+ Sbjct: 136 MTVPSGSSVGSLGMLICY 153 >UniRef50_Q89E80 Cluster: Bll7207 protein; n=1; Bradyrhizobium japonicum|Rep: Bll7207 protein - Bradyrhizobium japonicum Length = 307 Score = 45.2 bits (102), Expect = 0.002 Identities = 41/180 (22%), Positives = 78/180 (43%), Gaps = 15/180 (8%) Frame = +1 Query: 325 EQKKAIFNKVKKIIDVAGQEGVNIICFQEL-WNMPFAFCTREKQPWCEFAESAEDGPTTT 501 + ++ +++ +++ A G +++ F EL + F E + ++ E P Sbjct: 8 DSREHTLSRMLALLEEAAGRGASLVVFPELAFTTFFPRWLLEGEALDQYFERGMPNPAVA 67 Query: 502 --FLRELAIRYAMVIVSSILERDEKHSDILWNTAVVISDTGNVIGKHRKNHI-----PRV 660 F R A+R + + L D + +N A+++ G ++G++RK H+ PR Sbjct: 68 KLFDRARALRVGFYVGYAELTPDGRR----YNCAILVDRDGEILGRYRKVHLPGSVEPRP 123 Query: 661 G---DFNESNYYMEGNTGHPVF----AXRYGKIAVXICFGRDHVLNWMMFGXNGXEIVXI 819 G E Y+ G+ G P F A + + + IC R +W + G G E+V I Sbjct: 124 GARYQQLEKRYFEYGDLGFPAFRAGSAWAHAIMGMMICNDRRWPESWRVLGLQGVELVCI 183 >UniRef50_A6T2L9 Cluster: Nitrilase; n=1; Janthinobacterium sp. Marseille|Rep: Nitrilase - Janthinobacterium sp. (strain Marseille) (Minibacterium massiliensis) Length = 355 Score = 45.2 bits (102), Expect = 0.002 Identities = 39/155 (25%), Positives = 68/155 (43%), Gaps = 9/155 (5%) Frame = +1 Query: 316 PVNEQKKAIFNKVKKIIDVAGQEGVNIICFQELWNMPFA-FC-----TREKQPWCEFAES 477 P+ A +K +I A + G ++I F E + F +C + + + A S Sbjct: 16 PIYFDTPATIDKACDLIAEAARNGASLIAFPEAFVSAFPIWCGVWAPVETHEFFFKLASS 75 Query: 478 AED--GPTTTFLRELAIRYAMVIVSSILERDEKHSDILWNTAVVISDTGNVIGKHRKNHI 651 A + GP LRE A R+ + + I E +W+T ++I D G+++ +HRK Sbjct: 76 AIEINGPEVAQLREAARRHGVFVSMGINEGTPISMGCVWDTNILIGDDGSILNRHRK--- 132 Query: 652 PRVGDFNESNYYMEGN-TGHPVFAXRYGKIAVXIC 753 + E + G+ +G V R G+I +C Sbjct: 133 -LIATHWEKLAWASGDGSGLRVVDTRIGRIGALVC 166 >UniRef50_O30121 Cluster: Putative uncharacterized protein; n=1; Archaeoglobus fulgidus|Rep: Putative uncharacterized protein - Archaeoglobus fulgidus Length = 257 Score = 45.2 bits (102), Expect = 0.002 Identities = 28/86 (32%), Positives = 50/86 (58%) Frame = +1 Query: 499 TFLRELAIRYAMVIVSSILERDEKHSDILWNTAVVISDTGNVIGKHRKNHIPRVGDFNES 678 + L +++ + ++I++ + ER+ D L+N+AV+I G +IGK+RK H+ + NE Sbjct: 68 SLLLKISEQKDIMIITGVAERE---GDDLYNSAVIIHK-GKIIGKYRKTHLFPL--TNEK 121 Query: 679 NYYMEGNTGHPVFAXRYGKIAVXICF 756 Y+ G+ VF GKI + IC+ Sbjct: 122 KYFKAGDK-LEVFETHLGKIGLLICY 146 >UniRef50_Q4K4P2 Cluster: Hydrolase, carbon-nitrogen family; n=5; Bacteria|Rep: Hydrolase, carbon-nitrogen family - Pseudomonas fluorescens (strain Pf-5 / ATCC BAA-477) Length = 275 Score = 44.8 bits (101), Expect = 0.003 Identities = 37/128 (28%), Positives = 60/128 (46%) Frame = +1 Query: 373 AGQEGVNIICFQELWNMPFAFCTREKQPWCEFAESAEDGPTTTFLRELAIRYAMVIVSSI 552 A G ++ EL + F R + +ES DGPT + + LA +VIV Sbjct: 35 AAARGAQVVVLPELVQSGYVFSDRNEA--LALSESL-DGPTLSLWKTLAEELQVVIVGGF 91 Query: 553 LERDEKHSDILWNTAVVISDTGNVIGKHRKNHIPRVGDFNESNYYMEGNTGHPVFAXRYG 732 ER ++ + N+A ++ G + +RK H+ D E+ + G+ PV A R+G Sbjct: 92 CERLDQER--VANSAALVEPEGRLT-LYRKAHL---WD-RENLIFTPGDEPPPVVATRFG 144 Query: 733 KIAVXICF 756 IA+ IC+ Sbjct: 145 PIAMMICY 152 >UniRef50_Q6JHR5 Cluster: Aliphatic amidase; n=1; Saccharopolyspora spinosa|Rep: Aliphatic amidase - Saccharopolyspora spinosa Length = 308 Score = 44.4 bits (100), Expect = 0.004 Identities = 36/136 (26%), Positives = 61/136 (44%), Gaps = 1/136 (0%) Frame = +1 Query: 352 VKKIIDVAGQEGVNIICFQELWNMPFAFCTREKQPWCEFAESAEDGPTTTFLRELAIRYA 531 V ++I A + G +++ F E + + F + A D P L + R Sbjct: 42 VNEVISAA-ERGADLLVFPECYLHGYMFADADA---VHQAALPLDDPALLPLHHVVRRTG 97 Query: 532 MVIVSSILERDEKHSDILWNTAVVISDTGNVIGKHRKNHIPRVGDFNESNYYMEGNTGHP 711 + V +LER ++NTA+ + G +G +RK HIP +G + G+ G P Sbjct: 98 VHAVLGLLERGT--DGYVYNTALALGPAGT-LGHYRKQHIPFMG---ADRFVAPGDDGAP 151 Query: 712 -VFAXRYGKIAVXICF 756 VF +G++ + ICF Sbjct: 152 RVFDTPFGRVGMMICF 167 >UniRef50_Q1PXD4 Cluster: Similar to N-carbamoyl-D-amino acid hydrolase; n=1; Candidatus Kuenenia stuttgartiensis|Rep: Similar to N-carbamoyl-D-amino acid hydrolase - Candidatus Kuenenia stuttgartiensis Length = 277 Score = 44.4 bits (100), Expect = 0.004 Identities = 30/120 (25%), Positives = 60/120 (50%) Frame = +1 Query: 292 SIAVPTDRPVNEQKKAIFNKVKKIIDVAGQEGVNIICFQELWNMPFAFCTREKQPWCEFA 471 SIA V+++ K + N + +++ A Q+G +I E F+F +E++ FA Sbjct: 5 SIAAIQMCSVHDRNKNL-NTARVLMEKAVQKGARLIALPE----NFSFIGQEREN-ITFA 58 Query: 472 ESAEDGPTTTFLRELAIRYAMVIVSSILERDEKHSDILWNTAVVISDTGNVIGKHRKNHI 651 E E G FL++ ++++++ I+ + + NT +V +G +IG + K H+ Sbjct: 59 EERETGEIVHFLKKFSMKHSVAIIGGSVPLRSSSKAKVTNTCLVFDQSGVIIGSYDKIHL 118 >UniRef50_A3ZLM3 Cluster: Putative nitrilase; n=1; Blastopirellula marina DSM 3645|Rep: Putative nitrilase - Blastopirellula marina DSM 3645 Length = 258 Score = 44.4 bits (100), Expect = 0.004 Identities = 30/110 (27%), Positives = 55/110 (50%), Gaps = 1/110 (0%) Frame = +1 Query: 325 EQKKAIFNKVKKIIDVAGQEGVNIICFQELWNMPFAFCTREKQPWCEFAESAEDGPTTTF 504 E K+ +++I A + G ++ EL+N + E AE+ GPT Sbjct: 5 EDKELNLQTAERLIAQAAERGAQLVVLPELFNY-----LGRLENLVEHAETIS-GPTAVR 58 Query: 505 LRELAIRYAMVIVS-SILERDEKHSDILWNTAVVISDTGNVIGKHRKNHI 651 +R+ A+++ + +V+ S ER E S + +NT+++ G IG +RK H+ Sbjct: 59 MRKAALKHQIYLVAGSFAERSETESRV-FNTSLIFDPLGKQIGVYRKIHL 107 >UniRef50_A6TL48 Cluster: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; n=2; Clostridiaceae|Rep: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase - Alkaliphilus metalliredigens QYMF Length = 296 Score = 44.0 bits (99), Expect = 0.005 Identities = 29/109 (26%), Positives = 51/109 (46%) Frame = +1 Query: 487 GPTTTFLRELAIRYAMVIVSSILERDEKHSDILWNTAVVISDTGNVIGKHRKNHIPRVGD 666 G T +++LA +V + ER + ++ +N++++I D G +IGK+RK H P + Sbjct: 69 GRHTRDIQKLAKELGTHVVFPLYERGKNKREV-FNSSLMIDDRGEIIGKYRKTH-PFPTE 126 Query: 667 FNESNYYMEGNTGHPVFAXRYGKIAVXICFGRDHVLNWMMFGXNGXEIV 813 E + V + GKI + IC+ D + G EI+ Sbjct: 127 RKEGGGWTTPGNETVVVDTKLGKIGMIICYDGDFPELSRVLALKGAEII 175 >UniRef50_A6CCB9 Cluster: Predicted amidohydrolase; n=1; Planctomyces maris DSM 8797|Rep: Predicted amidohydrolase - Planctomyces maris DSM 8797 Length = 282 Score = 44.0 bits (99), Expect = 0.005 Identities = 37/135 (27%), Positives = 67/135 (49%) Frame = +1 Query: 352 VKKIIDVAGQEGVNIICFQELWNMPFAFCTREKQPWCEFAESAEDGPTTTFLRELAIRYA 531 ++KI + A G ++ F E + F + E+ +AES GP+T L+E+ Sbjct: 23 IEKIKETAAA-GASLTVFPECALTGYCFASLEEA--LPYAESIP-GPSTDRLQEICRELN 78 Query: 532 MVIVSSILERDEKHSDILWNTAVVISDTGNVIGKHRKNHIPRVGDFNESNYYMEGNTGHP 711 +V +LE+ E+ ++N AV+I+ G V+G +RK H+P +G + G+ Sbjct: 79 HSVVVGMLEQAEQG---VYNAAVLITPEG-VLGSYRKIHLPYLG---VDRFATPGDRDFA 131 Query: 712 VFAXRYGKIAVXICF 756 V++ I + IC+ Sbjct: 132 VYSHPEANIGLNICY 146 >UniRef50_Q6AMZ4 Cluster: Putative uncharacterized protein; n=1; Desulfotalea psychrophila|Rep: Putative uncharacterized protein - Desulfotalea psychrophila Length = 258 Score = 43.2 bits (97), Expect = 0.009 Identities = 30/111 (27%), Positives = 56/111 (50%) Frame = +1 Query: 319 VNEQKKAIFNKVKKIIDVAGQEGVNIICFQELWNMPFAFCTREKQPWCEFAESAEDGPTT 498 V + K A + + I++ + ++I E+WN F + AE + GPT Sbjct: 11 VEDDKAASIARARTEIELCRES--DLIILPEIWNTGFMNFAAYRS----LAEERK-GPTL 63 Query: 499 TFLRELAIRYAMVIVSSILERDEKHSDILWNTAVVISDTGNVIGKHRKNHI 651 + +RE+A++ + I S EK D +N++ +IS G+++G +RK H+ Sbjct: 64 SMVREMAVKTSSFIHSGSFV--EKIEDKYYNSSYLISPDGDILGNYRKIHL 112 >UniRef50_Q0LQX0 Cluster: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; n=1; Herpetosiphon aurantiacus ATCC 23779|Rep: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase - Herpetosiphon aurantiacus ATCC 23779 Length = 259 Score = 43.2 bits (97), Expect = 0.009 Identities = 27/81 (33%), Positives = 40/81 (49%) Frame = +1 Query: 514 LAIRYAMVIVSSILERDEKHSDILWNTAVVISDTGNVIGKHRKNHIPRVGDFNESNYYME 693 LA R+ + IV S+LERD + ++NTA + G + +RK H+ +G E Y Sbjct: 72 LAARHHLAIVGSLLERDGEQ---VYNTATLYDAQGKRLHSYRKTHL--IGLMQEDRYLAA 126 Query: 694 GNTGHPVFAXRYGKIAVXICF 756 G VF +G A IC+ Sbjct: 127 GQQAE-VFETAWGTSACAICY 146 >UniRef50_UPI000051A529 Cluster: PREDICTED: similar to Nitrilase and fragile histidine triad fusion protein CG7067-PA; n=1; Apis mellifera|Rep: PREDICTED: similar to Nitrilase and fragile histidine triad fusion protein CG7067-PA - Apis mellifera Length = 304 Score = 42.7 bits (96), Expect = 0.012 Identities = 37/161 (22%), Positives = 76/161 (47%), Gaps = 7/161 (4%) Frame = +1 Query: 295 IAVPTDRPVNEQKKAIFNKVKKIIDVAGQEGVNIICFQELWNMPFAFCTREKQPWCEFAE 474 +AV N+++K + V+++ + A +I F E + + K+ A+ Sbjct: 29 VAVCQMTSTNDKEKNL-QTVRELSEKAKHRAASIAFFPEACD----YLADSKKDTIAMAQ 83 Query: 475 SAEDGPTTTFLRELA-IRYAMVIVSSILERDEKHSDILWNTAVVISDTGNVIGKHRKNHI 651 + +G T T +E+A I + + I E + + + + NT ++I+ G ++ +RK H+ Sbjct: 84 TL-NGSTVTSYKEIAKINKIWLSLGGIHEALDNNREHISNTHILINSEGEIVSTYRKIHL 142 Query: 652 PRVGDFN------ESNYYMEGNTGHPVFAXRYGKIAVXICF 756 + + N ES+Y + G P + GK+A+ IC+ Sbjct: 143 FDMDNKNTGVRLMESDYVLPGQKIEPPISTPIGKLALSICY 183 >UniRef50_A2BKF1 Cluster: Predicted amidohydrolase; n=1; Hyperthermus butylicus DSM 5456|Rep: Predicted amidohydrolase - Hyperthermus butylicus (strain DSM 5456 / JCM 9403) Length = 272 Score = 42.7 bits (96), Expect = 0.012 Identities = 28/96 (29%), Positives = 42/96 (43%) Frame = +1 Query: 469 AESAEDGPTTTFLRELAIRYAMVIVSSILERDEKHSDILWNTAVVISDTGNVIGKHRKNH 648 AE+ +D P FL E++ Y VIVS LER D +++ V++ V +RK Sbjct: 60 AENPKDSPFIRFLEEISSEYTAVIVSGFLERS---GDCAYSSIVMVEPGKEVQVVYRKTV 116 Query: 649 IPRVGDFNESNYYMEGNTGHPVFAXRYGKIAVXICF 756 + ES G PV R ++ +CF Sbjct: 117 LFDALGVRESKSLCRGEQPPPVLEVRGVRVGFIVCF 152 >UniRef50_Q72HE8 Cluster: Beta-ureidopropionase; n=2; Thermus thermophilus|Rep: Beta-ureidopropionase - Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) Length = 292 Score = 42.3 bits (95), Expect = 0.015 Identities = 26/94 (27%), Positives = 42/94 (44%) Frame = +1 Query: 538 IVSSILERDEKHSDILWNTAVVISDTGNVIGKHRKNHIPRVGDFNESNYYMEGNTGHPVF 717 +V ERDE +N+A + V+ HRK +P G F+E Y G F Sbjct: 85 VVVGFYERDE---GAYYNSAAYLELPHRVVHVHRKVFLPTYGVFDEERYLARGRRVE-AF 140 Query: 718 AXRYGKIAVXICFGRDHVLNWMMFGXNGXEIVXI 819 R+G+ A+ IC H + + +G E++ + Sbjct: 141 RTRFGRAALLICEDFWHSITATIAALDGAEVIYV 174 >UniRef50_Q1AWK1 Cluster: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; n=4; Bacteria|Rep: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase - Rubrobacter xylanophilus (strain DSM 9941 / NBRC 16129) Length = 276 Score = 42.3 bits (95), Expect = 0.015 Identities = 41/158 (25%), Positives = 71/158 (44%), Gaps = 5/158 (3%) Frame = +1 Query: 361 IIDVAGQEGVNIICFQELWNMPFAFCTREKQPWCEFAESAEDGPTTTFLRELAIRYAMVI 540 +I A G ++ ELW+ C ++ + E AE GPTT FL LA + + Sbjct: 29 LIREAAAAGATLVALPELWS-----CHGLEEVYRENAEPIP-GPTTEFLGSLARELGIYL 82 Query: 541 V-SSILERDEKHSDILWNTAVVISDTGNVIGKHRKNHIPRVGDFNESNYYMEGN--TGHP 711 + SILER S+ L NT+ + + G+++ +RK H+ V + + Y N G Sbjct: 83 LGGSILER-VSGSERLGNTSTLYAPDGSLVAVYRKVHLFDV-EVSGRRYLESANIAPGGE 140 Query: 712 VFAXRYGKIAV--XICFGRDHVLNWMMFGXNGXEIVXI 819 A + G + V +C+ + + G E++ + Sbjct: 141 AVAAKAGPVTVGLSVCYDVRFPELYRLLALRGAEVLAV 178 >UniRef50_Q8W0T9 Cluster: Putative uncharacterized protein SB35P03.20; n=1; Sorghum bicolor|Rep: Putative uncharacterized protein SB35P03.20 - Sorghum bicolor (Sorghum) (Sorghum vulgare) Length = 580 Score = 42.3 bits (95), Expect = 0.015 Identities = 34/123 (27%), Positives = 57/123 (46%), Gaps = 7/123 (5%) Frame = +1 Query: 406 QELWNMPFAFCTREKQPWCEFAESAEDG--PTTTFLRELAIRYAMVIVSSILERDEKHSD 579 +E+W+ C+ + +AE + G P+ + L E+A + IV + EK S Sbjct: 385 KEIWS-----CSYAMETLASYAEDIDGGESPSISMLSEVAAAKKITIVGGSIP--EKASG 437 Query: 580 ILWNTAVVISDTGNVIGKHRKNHIPRV---GD--FNESNYYMEGNTGHPVFAXRYGKIAV 744 ++NT VI G ++ KHRK H+ + GD ES+ + G + G+I + Sbjct: 438 KMFNTCCVIGPDGKILAKHRKLHLFEIDIPGDITLKESDTF-TGGQETTIVDTDVGRIGI 496 Query: 745 XIC 753 IC Sbjct: 497 GIC 499 >UniRef50_A3EVA0 Cluster: NAD synthase; n=4; Bacteria|Rep: NAD synthase - Leptospirillum sp. Group II UBA Length = 592 Score = 41.5 bits (93), Expect = 0.027 Identities = 20/59 (33%), Positives = 33/59 (55%) Frame = +1 Query: 577 DILWNTAVVISDTGNVIGKHRKNHIPRVGDFNESNYYMEGNTGHPVFAXRYGKIAVXIC 753 D ++N A V+ G + G +RK ++P G F+E+ Y+ EG PV R ++ + IC Sbjct: 90 DDIYNAAAVLHG-GKLHGIYRKQYLPNYGVFDENRYFQEG-VESPVLEYRSARLGINIC 146 >UniRef50_A0L7H1 Cluster: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; n=2; Proteobacteria|Rep: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase - Magnetococcus sp. (strain MC-1) Length = 275 Score = 41.5 bits (93), Expect = 0.027 Identities = 30/141 (21%), Positives = 64/141 (45%), Gaps = 5/141 (3%) Frame = +1 Query: 349 KVKKIIDVAGQEGVNIICFQELWNMPFAFCTREKQPWCEFAESAEDGPTTTFLRELAIRY 528 + +++++ A G ++ E F+F +++ E + GP+ ++ A R+ Sbjct: 26 RAEQLLEEAATAGAKLLVLPE----NFSFFGADEKEKLAHQEDPQHGPSLRMVQAFAQRH 81 Query: 529 AMVIVSSILERDEKHSDILWNTAVVISDTGNVIGKHRKNHIPRVGDFNESNYYMEGNT-- 702 +V+ + D S + N++ V++D G V+ ++ K H+ V N Y E + Sbjct: 82 GAWVVAGSIPTDVGESQRVANSSFVVNDQGQVVARYDKIHLFDV-TLNGGEGYRESDMIR 140 Query: 703 --GHPVFAXR-YGKIAVXICF 756 PV +G+I + IC+ Sbjct: 141 AGSQPVVVDSPFGRIGLSICY 161 >UniRef50_Q6L0F7 Cluster: Carbon-nitrogen hydrolase family; n=2; Thermoplasmatales|Rep: Carbon-nitrogen hydrolase family - Picrophilus torridus Length = 256 Score = 41.5 bits (93), Expect = 0.027 Identities = 37/163 (22%), Positives = 75/163 (46%) Frame = +1 Query: 331 KKAIFNKVKKIIDVAGQEGVNIICFQELWNMPFAFCTREKQPWCEFAESAEDGPTTTFLR 510 K++ K++K ++A G ++I F E F F + +K+ E AE +++ Sbjct: 15 KESNLEKLRKYTEIAASNGADLIVFPEY----FMFYSNDKKYLNENAEPING----IWVK 66 Query: 511 ELAIRYAMVIVSSILERDEKHSDILWNTAVVISDTGNVIGKHRKNHIPRVGDFNESNYYM 690 + + +S I+ +E + + +++TAV IS G+V G +RK + + ES+ Y Sbjct: 67 NVIKIFNENSISGIVCINELNDNNVFDTAVYIS--GDVKGYYRKKMLYDAFGYRESDIYK 124 Query: 691 EGNTGHPVFAXRYGKIAVXICFGRDHVLNWMMFGXNGXEIVXI 819 GN ++ + IC+ + + NG +++ I Sbjct: 125 SGNGPFNLYRINDISFGILICYEIRFPELFRNYSKNGADMIII 167 >UniRef50_A1HPP3 Cluster: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; n=1; Thermosinus carboxydivorans Nor1|Rep: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase - Thermosinus carboxydivorans Nor1 Length = 259 Score = 41.1 bits (92), Expect = 0.036 Identities = 44/165 (26%), Positives = 69/165 (41%), Gaps = 2/165 (1%) Frame = +1 Query: 268 VKVGIIQHSIAVPTDRPVNEQKKAIFNKVKKIIDVAGQEGVNIICFQELWNMPFAFCTRE 447 +KV ++Q I + D N QK +++ + G + ELW + Sbjct: 1 MKVALLQMDIVLG-DVEANRQKALA------MLEQGAKAGAKLFVLPELWTTGYVLDQLL 53 Query: 448 KQPWCEFAESAEDGPTTTFLRELAIRYAMVIVS-SILE-RDEKHSDILWNTAVVISDTGN 621 K + GPT L++ A + IV SI E RD K ++NT VI G Sbjct: 54 K------IGEPDGGPTVKMLQQFAKDNGVEIVGGSIAEIRDGK----VYNTIYVIDSAGE 103 Query: 622 VIGKHRKNHIPRVGDFNESNYYMEGNTGHPVFAXRYGKIAVXICF 756 V+GK+ K H+ V +E Y G+ +F +GK +C+ Sbjct: 104 VVGKYSKIHL--VPMMDEEKYLTPGDR-QGLFDLSFGKAGGIVCY 145 >UniRef50_Q8ZVX6 Cluster: Nitrilase, conjectural; n=4; Pyrobaculum|Rep: Nitrilase, conjectural - Pyrobaculum aerophilum Length = 258 Score = 41.1 bits (92), Expect = 0.036 Identities = 23/84 (27%), Positives = 37/84 (44%) Frame = +1 Query: 505 LRELAIRYAMVIVSSILERDEKHSDILWNTAVVISDTGNVIGKHRKNHIPRVGDFNESNY 684 L ++A + LER + ++NT V++S G +G +RK H+ + ES Sbjct: 61 LAKIAAETGAYVAGGFLERGPRPK--VFNTTVLVSPAGKAVGTYRKTHLFDAYGYKESEA 118 Query: 685 YMEGNTGHPVFAXRYGKIAVXICF 756 G +F R KI +CF Sbjct: 119 VEPGGELSGIFDVRQIKIGFAVCF 142 >UniRef50_A6Q8M5 Cluster: Carbon-nitrogen hydrolase family protein; n=1; Sulfurovum sp. NBC37-1|Rep: Carbon-nitrogen hydrolase family protein - Sulfurovum sp. (strain NBC37-1) Length = 377 Score = 40.7 bits (91), Expect = 0.047 Identities = 34/139 (24%), Positives = 64/139 (46%), Gaps = 3/139 (2%) Frame = +1 Query: 349 KVKKIIDVAGQEGVNIICFQELWNMPFAFCTREKQPWCEFAESAEDGPTTTFLRELAIRY 528 +++ I +A ++ + ++ F EL+ + + +F +DGP T RELA R Sbjct: 85 RMEHAIRLAKEKHIQLLSFPELYIPGYTLSPAMVKKVAQF----KDGPAVTKARELARRN 140 Query: 529 AMVIVSSILERDEKHSD---ILWNTAVVISDTGNVIGKHRKNHIPRVGDFNESNYYMEGN 699 + I+ E+ KHSD +++ VI + G ++ +RK H+ G N+ GN Sbjct: 141 NIAILLPYAEK-AKHSDGTLAYYDSIAVIDEHGKLLNSYRKTHL--YGQQERDNWSF-GN 196 Query: 700 TGHPVFAXRYGKIAVXICF 756 + V+ + V C+ Sbjct: 197 GDYQVYHFFGFPVGVLNCY 215 >UniRef50_A5GU42 Cluster: Nitrilase-related protein; n=1; Synechococcus sp. RCC307|Rep: Nitrilase-related protein - Synechococcus sp. (strain RCC307) Length = 305 Score = 40.7 bits (91), Expect = 0.047 Identities = 30/131 (22%), Positives = 62/131 (47%), Gaps = 5/131 (3%) Frame = +1 Query: 274 VGIIQHSIAVPTDRPVNEQKKAIFNKVKKIIDVAG-QEGVNIICFQELWNMPFAF--CTR 444 V ++Q ++ + VN Q+ + + +++ + AG ++ E+WN P+ Sbjct: 7 VALVQFQVS--PEPQVNRQQ--VCHWLEQAMTQAGTSSSPKLLMLPEVWNSPYQAERFAE 62 Query: 445 EKQPWCEFAESAEDGPTTTF--LRELAIRYAMVIVSSILERDEKHSDILWNTAVVISDTG 618 +P E DGP+ + + + A+ + + +++ + I +NTA VIS G Sbjct: 63 FAEPIPELGADLRDGPSDSLKVVADFAVSHRVSVIAGSIPECSSDGRI-FNTATVISPAG 121 Query: 619 NVIGKHRKNHI 651 ++ KHRK H+ Sbjct: 122 CLLAKHRKMHL 132 >UniRef50_A3M2Z7 Cluster: Putative glutamine-dependent NAD(+) synthetase (NAD(+) synthase); n=1; Acinetobacter baumannii ATCC 17978|Rep: Putative glutamine-dependent NAD(+) synthetase (NAD(+) synthase) - Acinetobacter baumannii (strain ATCC 17978 / NCDC KC 755) Length = 364 Score = 40.7 bits (91), Expect = 0.047 Identities = 21/56 (37%), Positives = 32/56 (57%) Frame = +1 Query: 586 WNTAVVISDTGNVIGKHRKNHIPRVGDFNESNYYMEGNTGHPVFAXRYGKIAVXIC 753 +N+A V+ D G V+G K+++P G F+E Y+ +G+ H VF K V IC Sbjct: 70 YNSAAVMKD-GQVLGVFNKHNLPNYGVFDEKRYFQKGHQ-HLVFEYLGHKFGVLIC 123 >UniRef50_UPI0000E472D9 Cluster: PREDICTED: similar to Ureidopropionase, beta, partial; n=1; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to Ureidopropionase, beta, partial - Strongylocentrotus purpuratus Length = 57 Score = 40.3 bits (90), Expect = 0.062 Identities = 16/29 (55%), Positives = 22/29 (75%) Frame = +1 Query: 244 EQTRPPRIVKVGIIQHSIAVPTDRPVNEQ 330 EQ R PR+V++G+IQ+ I +PT PV EQ Sbjct: 29 EQLRSPRLVRIGLIQNQIVLPTTAPVKEQ 57 >UniRef50_Q5LLB2 Cluster: Nitrilase family protein; n=7; Bacteria|Rep: Nitrilase family protein - Silicibacter pomeroyi Length = 344 Score = 40.3 bits (90), Expect = 0.062 Identities = 30/106 (28%), Positives = 44/106 (41%), Gaps = 8/106 (7%) Frame = +1 Query: 349 KVKKIIDVAGQEGVNIICFQELWNMPFAFCTREKQP-----WCEFAESAE---DGPTTTF 504 K +I A G ++ F E++ + + P W E A DGP Sbjct: 30 KAVDLIAEAAGNGAELVVFPEVFIPGYPYWNWITDPVTGGAWFEKLVRASVFADGPEIDV 89 Query: 505 LRELAIRYAMVIVSSILERDEKHSDILWNTAVVISDTGNVIGKHRK 642 +R+ A + +V + ER L+NT + I G VIGKHRK Sbjct: 90 IRDAARAHGCHVVMGLNERSPVSLGALYNTLLFIGPDGEVIGKHRK 135 >UniRef50_Q5MD29 Cluster: CtaJ; n=2; Cystobacteraceae|Rep: CtaJ - Cystobacter fuscus Length = 343 Score = 40.3 bits (90), Expect = 0.062 Identities = 36/134 (26%), Positives = 60/134 (44%), Gaps = 1/134 (0%) Frame = +1 Query: 355 KKIIDVAGQEGVNIICFQELWNMPFAFCTREKQPWCEFAESAEDGPTTTFLRELAIRYAM 534 + I A ++G ++ E + P + + + W A DGPT FL++ A ++ + Sbjct: 34 RPFIQSAAEQGAQLLLLPEFY--PTGYL-QSPEVWR--AGETLDGPTVRFLKQQAAQWRV 88 Query: 535 VIVSSILERDEKHSDILWNTAVVISDTGNVIGKHRKNHIPRVGDFNESNYYMEGNTGHP- 711 + +S LE D D +N V++S G V K RK P + Y+ G+ P Sbjct: 89 HLGTSFLEAD---GDDFYNAFVLVSPAGQV-HKVRKRRAP-----SYEAYWFRGSGDDPC 139 Query: 712 VFAXRYGKIAVXIC 753 V G+ +V IC Sbjct: 140 VIDCELGRFSVGIC 153 >UniRef50_Q1F028 Cluster: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; n=1; Clostridium oremlandii OhILAs|Rep: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase - Clostridium oremlandii OhILAs Length = 261 Score = 40.3 bits (90), Expect = 0.062 Identities = 33/138 (23%), Positives = 64/138 (46%) Frame = +1 Query: 343 FNKVKKIIDVAGQEGVNIICFQELWNMPFAFCTREKQPWCEFAESAEDGPTTTFLRELAI 522 F K +++I +A +E + I E W+ F F + +C+ + + +EL + Sbjct: 19 FKKAEELIRLAAKENPDTIALPETWSTGF-FPKENIKEFCDQNGNRTKRLFSKLSKELNV 77 Query: 523 RYAMVIVSSILERDEKHSDILWNTAVVISDTGNVIGKHRKNHIPRVGDFNESNYYMEGNT 702 +I S++ +EK D ++NT+ + + G I ++ K H+ E Y+ +G + Sbjct: 78 N---IIAGSVI--NEKQ-DGIYNTSYIFNKQGECIAEYDKTHL--FSYMGEDQYFEKG-S 128 Query: 703 GHPVFAXRYGKIAVXICF 756 G VF K + IC+ Sbjct: 129 GITVFELDGIKCGIVICY 146 >UniRef50_A5V6Z2 Cluster: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; n=1; Sphingomonas wittichii RW1|Rep: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase - Sphingomonas wittichii RW1 Length = 384 Score = 40.3 bits (90), Expect = 0.062 Identities = 35/121 (28%), Positives = 53/121 (43%), Gaps = 11/121 (9%) Frame = +1 Query: 484 DGPTTTFLRELAIRYAMVIVSS-ILERDEKHSDILWNTAVVISDTGNVIGKHRKNHIP-R 657 DGP L E+A Y + I ++ER ++ D +NTA +I +G V+ ++ K HIP Sbjct: 84 DGPEMRRLGEVAKEYNLYIAGGGVVERVKEFPDRWFNTAFIIGPSGEVVLRYHKWHIPAS 143 Query: 658 VG-------DFNESNYYMEG--NTGHPVFAXRYGKIAVXICFGRDHVLNWMMFGXNGXEI 810 +G F+E G +T PV GK+ C G NG E+ Sbjct: 144 IGLGTSPHDIFDEYKEVFGGDISTLFPVIDTEIGKLGTMTCHDGCTPEVSRALGYNGVEV 203 Query: 811 V 813 + Sbjct: 204 I 204 >UniRef50_A4WA35 Cluster: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; n=12; Bacteria|Rep: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase - Enterobacter sp. 638 Length = 326 Score = 40.3 bits (90), Expect = 0.062 Identities = 31/104 (29%), Positives = 49/104 (47%), Gaps = 5/104 (4%) Frame = +1 Query: 352 VKKIIDVAGQEGVNIICFQEL-----WNMPFAFCTREKQPWCEFAESAEDGPTTTFLREL 516 ++K I+ A E VNI+ F E+ W++P AE + P+ T +R L Sbjct: 28 IEKFIEQAALEQVNILVFPEMCITGYWHVPKLTAAEVSA----LAEPIAESPSLTLIRSL 83 Query: 517 AIRYAMVIVSSILERDEKHSDILWNTAVVISDTGNVIGKHRKNH 648 AI++ M+I ++ER + L+N V G + HRK H Sbjct: 84 AIKHQMLIGVGLIERAD--DGRLYNAYVACMPDG-TMHTHRKLH 124 >UniRef50_Q2JDM2 Cluster: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; n=12; Actinomycetales|Rep: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase - Frankia sp. (strain CcI3) Length = 404 Score = 39.9 bits (89), Expect = 0.083 Identities = 41/159 (25%), Positives = 66/159 (41%), Gaps = 1/159 (0%) Frame = +1 Query: 346 NKVKKIIDVAGQEGVNIICFQELWNMPFAFCTREKQPWCEFAESAEDGPTTTFLRELAI- 522 ++V++++ Q +++ ELW + R E A GPT T LRE A Sbjct: 22 DRVRRVLGEIRQTQADLVVLPELWVTGYFHFDRY-----EAEAEALTGPTVTALREAARE 76 Query: 523 RYAMVIVSSILERDEKHSDILWNTAVVISDTGNVIGKHRKNHIPRVGDFNESNYYMEGNT 702 R ++ SI+ER L+NT V+I G + +RK H+ G E+ G T Sbjct: 77 RGCHLVAGSIVERSADGR--LFNTTVLIGPDGMIRHAYRKVHLFGYGS-AEARLLTPGAT 133 Query: 703 GHPVFAXRYGKIAVXICFGRDHVLNWMMFGXNGXEIVXI 819 V G + + C+ + + G EIV + Sbjct: 134 VGTV-PTELGIVGLATCYDLRFPELFRLLAEGGAEIVVV 171 >UniRef50_A7FDR9 Cluster: Hydrolase, carbon-nitrogen family protein; n=16; Enterobacteriaceae|Rep: Hydrolase, carbon-nitrogen family protein - Yersinia pseudotuberculosis IP 31758 Length = 289 Score = 39.9 bits (89), Expect = 0.083 Identities = 32/124 (25%), Positives = 58/124 (46%), Gaps = 7/124 (5%) Frame = +1 Query: 469 AESAEDGPTTTFLRELAIRYAMVI-VSSILERDEKHSDILWNTAVVISDTGNVIGKHRKN 645 AE DGP +RE+A RY + I V S+ + D++ +++++ D G + ++ K Sbjct: 57 AEQHNDGPLQQEVREMARRYGVWIQVGSMPMVSRESPDLITSSSLLFDDQGELKARYDKI 116 Query: 646 HIPRVGDFNE-SNYYMEGNTGHP-----VFAXRYGKIAVXICFGRDHVLNWMMFGXNGXE 807 H+ V D N+ +Y E +T P V G++ + IC+ + G E Sbjct: 117 HMFDV-DINDIHGHYRESDTYQPGQQLTVVDTPVGRLGMTICYDLRFPGLFQALRAQGAE 175 Query: 808 IVXI 819 I+ + Sbjct: 176 IISV 179 >UniRef50_A0JSY8 Cluster: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; n=4; Actinomycetales|Rep: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase - Arthrobacter sp. (strain FB24) Length = 344 Score = 39.9 bits (89), Expect = 0.083 Identities = 24/82 (29%), Positives = 41/82 (50%), Gaps = 4/82 (4%) Frame = +1 Query: 463 EFAESAEDGPTTTFLRELAIRYAMVIVSSILERDEKH--SD--ILWNTAVVISDTGNVIG 630 + AE GPT F A R+ + + +S+ +R E SD + NT+V++S G ++ Sbjct: 91 DLAEDLLTGPTFRFAAGAARRHGITVHASLYQRAENPDGSDDGLGLNTSVLVSPEGELLA 150 Query: 631 KHRKNHIPRVGDFNESNYYMEG 696 + K HIP + E ++ G Sbjct: 151 RTHKLHIPVTAGYYEDKFFRPG 172 >UniRef50_A5AAF3 Cluster: Contig An02c0310, complete genome; n=5; Trichocomaceae|Rep: Contig An02c0310, complete genome - Aspergillus niger Length = 320 Score = 39.9 bits (89), Expect = 0.083 Identities = 26/88 (29%), Positives = 44/88 (50%), Gaps = 2/88 (2%) Frame = +1 Query: 562 DEKHSDILWNTAVVISDTGNVIGKHRKNHIPRVGDFNESNYYM--EGNTGHPVFAXRYGK 735 +E+ +L+NTA IS+ G+++G +RK +I ++ Y+ G+ H VF GK Sbjct: 97 NEQQQPVLYNTAYFISNDGSILGHYRKKNI-----WHPERPYLTSSGHDPHEVFDTPIGK 151 Query: 736 IAVXICFGRDHVLNWMMFGXNGXEIVXI 819 + + IC+ + G EIV I Sbjct: 152 VGLLICWDLAFPEAFRELICKGAEIVVI 179 >UniRef50_Q9HIW8 Cluster: Nitrilase related protein; n=2; Thermoplasma|Rep: Nitrilase related protein - Thermoplasma acidophilum Length = 270 Score = 39.9 bits (89), Expect = 0.083 Identities = 29/130 (22%), Positives = 57/130 (43%) Frame = +1 Query: 484 DGPTTTFLRELAIRYAMVIVSSILERDEKHSDILWNTAVVISDTGNVIGKHRKNHIPRVG 663 DG + E+A + I+ +I ER++ + +NTA+ I + G ++ K+RK H+ Sbjct: 60 DGKFVKSITEIARSESQKIILNIPERNQYNLKP-FNTAIYIDELGLIL-KYRKLHLFDAF 117 Query: 664 DFNESNYYMEGNTGHPVFAXRYGKIAVXICFGRDHVLNWMMFGXNGXEIVXIRXXXSPXK 843 F ES+ + +G+ +F + V IC+ M +G +++ + + Sbjct: 118 GFRESSVFEKGDARPAIFNGSGDPLGVLICYDLRFPEPARMLALDGAKLIIYQAGWFAGE 177 Query: 844 XXXXMWNVXL 873 W L Sbjct: 178 RKYDQWKTLL 187 >UniRef50_Q6TGW8 Cluster: Nit protein 2; n=22; Fungi/Metazoa group|Rep: Nit protein 2 - Danio rerio (Zebrafish) (Brachydanio rerio) Length = 277 Score = 39.5 bits (88), Expect = 0.11 Identities = 37/151 (24%), Positives = 64/151 (42%), Gaps = 5/151 (3%) Frame = +1 Query: 319 VNEQKKAIFNKVKKIIDVAGQEGVNIICFQELWNMPFAFCTREKQPWCEFAESAEDGPTT 498 V++ K + + ++ A +G ++ E +N P+ + E+AE G +T Sbjct: 13 VSKIKADNLGRAQTLVTEAAGQGAKVVVLPECFNSPYGTGFFK-----EYAEKIP-GEST 66 Query: 499 TFLRELAIRYAMVIVSSILERDEKHSDILWNTAVVISDTGNVIGKHRKNH-----IPRVG 663 L E A + + +V + E+ L+NT V G ++ HRK H +P Sbjct: 67 QVLSETAKKCGIYLVGGSIP--EEDGGKLYNTCSVFGPDGTLLVTHRKIHLFDIDVPGKI 124 Query: 664 DFNESNYYMEGNTGHPVFAXRYGKIAVXICF 756 F ES G + +F Y K+ V IC+ Sbjct: 125 RFQESETLSPGKS-LSMFETPYCKVGVGICY 154 >UniRef50_Q75TH8 Cluster: Putative uncharacterized protein GSB07; n=1; Geobacillus stearothermophilus|Rep: Putative uncharacterized protein GSB07 - Bacillus stearothermophilus (Geobacillus stearothermophilus) Length = 273 Score = 39.5 bits (88), Expect = 0.11 Identities = 38/157 (24%), Positives = 69/157 (43%), Gaps = 3/157 (1%) Frame = +1 Query: 295 IAVPTDRPVNEQKKAIFNKVKKIIDVAGQE--GVNIICFQELWNMPFAFCTREKQPWCEF 468 IA+ P + A K++ II ++ V ++ F EL+ + K+ Sbjct: 7 IALAQMMPADGDIGANLAKMETIIHECKRKFPNVRLLLFPELYTTGYVLSEMLKE----- 61 Query: 469 AESAEDGPTTTFLRELAIRYAMVIVSSILERDEKHSDILWNTAVVISDTGNVIGKHRKNH 648 A DG T + +LA + + + +E+D H+ L+N+ ++I G IG +RK H Sbjct: 62 AAQTWDGSTFQHMSQLAQTFQLYLAYGYVEKD--HTGNLYNSLMLIDPNGQCIGNYRKIH 119 Query: 649 IPRVGDFNESNYYMEGNTGHPVFA-XRYGKIAVXICF 756 + E ++ +G PV G+I + IC+ Sbjct: 120 LTPF----EKAWFSKG--AEPVLVDTELGRIGLMICW 150 >UniRef50_Q1AZG5 Cluster: Nitrilase; n=1; Rubrobacter xylanophilus DSM 9941|Rep: Nitrilase - Rubrobacter xylanophilus (strain DSM 9941 / NBRC 16129) Length = 359 Score = 39.5 bits (88), Expect = 0.11 Identities = 36/154 (23%), Positives = 68/154 (44%), Gaps = 8/154 (5%) Frame = +1 Query: 316 PVNEQKKAIFNKVKKIIDVAGQEGVNIICFQE-------LWNMPFAFCTREKQPWCEFAE 474 PV+ + A +K++ ++ A + G ++ F E +WN+ + F Sbjct: 18 PVHLKPDATVDKLESLVAEAARGGAQLVVFSESFIPAFPVWNLVLPPVDQHDLFRRLFLN 77 Query: 475 SA-EDGPTTTFLRELAIRYAMVIVSSILERDEKHSDILWNTAVVISDTGNVIGKHRKNHI 651 S GP T L E+A R+ + + + ER L+NT ++ + TG ++ HR+ + Sbjct: 78 SVLVPGPITRRLAEIAKRHDVYLSVGVTERTNISMGCLYNTNLLFAPTGELL-NHRRKLV 136 Query: 652 PRVGDFNESNYYMEGNTGHPVFAXRYGKIAVXIC 753 P + ++ + + + PV G I V IC Sbjct: 137 PTWAE-KLTHAWGDASDLRPV-QTELGNIGVLIC 168 >UniRef50_Q15ZG7 Cluster: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; n=2; Alteromonadales|Rep: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase - Pseudoalteromonas atlantica (strain T6c / BAA-1087) Length = 276 Score = 39.5 bits (88), Expect = 0.11 Identities = 27/102 (26%), Positives = 51/102 (50%), Gaps = 6/102 (5%) Frame = +1 Query: 469 AESAEDGPTTTFLRELAIRYAMVIVSSILERDEKHSDILWNTAVVISDTGNVIGKHRKNH 648 AES DGP L +A +Y + +V+ + ++ D + ++I+D G + +++K H Sbjct: 57 AESLGDGPIQARLMGMAKQYGVWLVAGSMPLKSENPDKFTASCLLINDAGERVTEYQKIH 116 Query: 649 I--PRVGD----FNESNYYMEGNTGHPVFAXRYGKIAVXICF 756 + +V D + ES Y G+T V +G + + IC+ Sbjct: 117 LFDVQVADNTKTYCESKYTQAGSTLVSVPDTPFGHLGLAICY 158 >UniRef50_Q8WUF0 Cluster: Nitrilase family member 2; n=28; cellular organisms|Rep: Nitrilase family member 2 - Homo sapiens (Human) Length = 276 Score = 39.5 bits (88), Expect = 0.11 Identities = 33/133 (24%), Positives = 60/133 (45%), Gaps = 5/133 (3%) Frame = +1 Query: 373 AGQEGVNIICFQELWNMPFAFCTREKQPWCEFAESAEDGPTTTFLRELAIRYAMVIVSSI 552 A +G I+ E +N P+ + + E+AE G +T L E+A ++ ++ Sbjct: 31 AATQGAKIVSLPECFNSPYG-----AKYFPEYAEKIP-GESTQKLSEVAKECSIYLIGGS 84 Query: 553 LERDEKHSDILWNTAVVISDTGNVIGKHRKNH-----IPRVGDFNESNYYMEGNTGHPVF 717 + E+ + L+NT V G ++ K+RK H +P F ES G++ F Sbjct: 85 IP--EEDAGKLYNTCAVFGPDGTLLAKYRKIHLFDIDVPGKITFQESKTLSPGDS-FSTF 141 Query: 718 AXRYGKIAVXICF 756 Y ++ + IC+ Sbjct: 142 DTPYCRVGLGICY 154 >UniRef50_Q8TPH5 Cluster: Carbon-nitrogen hydrolase; n=1; Methanosarcina acetivorans|Rep: Carbon-nitrogen hydrolase - Methanosarcina acetivorans Length = 459 Score = 39.5 bits (88), Expect = 0.11 Identities = 20/50 (40%), Positives = 30/50 (60%), Gaps = 1/50 (2%) Frame = +1 Query: 268 VKVGIIQHSIAVPTDRPVN-EQKKAIFNKVKKIIDVAGQEGVNIICFQEL 414 VKVG +Q + + P+ + K+A K+ K +D+A +E VNIIC EL Sbjct: 194 VKVGTVQIAFELSESFPLEIKNKEATKEKIFKALDIANKENVNIICLPEL 243 >UniRef50_Q5V604 Cluster: Nitrilase; n=2; Halobacteriaceae|Rep: Nitrilase - Haloarcula marismortui (Halobacterium marismortui) Length = 366 Score = 39.5 bits (88), Expect = 0.11 Identities = 29/126 (23%), Positives = 54/126 (42%), Gaps = 9/126 (7%) Frame = +1 Query: 292 SIAVPTDRPVNEQKKAIFNKVKKIIDVAGQEGVNIICFQELW--NMPFAFCTREKQPWCE 465 ++A PV K+ +K + I+ AG++G +I+ F E + P+ + W + Sbjct: 7 TLAAAQVEPVYHDKEGTLDKTCRYIEQAGRDGADIVVFPETYFPGYPYWRGSVSISRWTD 66 Query: 466 FAESAE------DGPTTTFLRELAIRYAMVIVSSILE-RDEKHSDILWNTAVVISDTGNV 624 + D L E + +V E D + S+ L+N+ +TG + Sbjct: 67 LMVDLQKNSLHVDDEAIEILGEAVAEADLTLVLGTNEISDRQGSETLYNSLFYFDNTGEL 126 Query: 625 IGKHRK 642 +G+HRK Sbjct: 127 MGRHRK 132 >UniRef50_Q3W243 Cluster: GCN5-related N-acetyltransferase:AIR synthase related protein:Nitrilase/cyanide hydratase and apolipoprotein N- acyltransferase:AIR synthase related protein, C-terminal; n=14; Actinomycetales|Rep: GCN5-related N-acetyltransferase:AIR synthase related protein:Nitrilase/cyanide hydratase and apolipoprotein N- acyltransferase:AIR synthase related protein, C-terminal - Frankia sp. EAN1pec Length = 807 Score = 39.1 bits (87), Expect = 0.14 Identities = 31/93 (33%), Positives = 45/93 (48%) Frame = +1 Query: 484 DGPTTTFLRELAIRYAMVIVSSILERDEKHSDILWNTAVVISDTGNVIGKHRKNHIPRVG 663 DGP T R AI MV+ + ERD ++ +N+AV + G V+G+HRK H P Sbjct: 562 DGPEIT--RLAAIAGDMVVCAGYAERDGRYR---YNSAVCVHGDG-VLGRHRKVHQP--- 612 Query: 664 DFNESNYYMEGNTGHPVFAXRYGKIAVXICFGR 762 ES Y E F G++ + IC+ + Sbjct: 613 -LGESLAY-EAGRSFTAFDSPLGRMGMMICYDK 643 >UniRef50_UPI0000E1FE2F Cluster: PREDICTED: similar to Nitrilase family, member 2; n=2; Coelomata|Rep: PREDICTED: similar to Nitrilase family, member 2 - Pan troglodytes Length = 411 Score = 38.7 bits (86), Expect = 0.19 Identities = 33/133 (24%), Positives = 60/133 (45%), Gaps = 5/133 (3%) Frame = +1 Query: 373 AGQEGVNIICFQELWNMPFAFCTREKQPWCEFAESAEDGPTTTFLRELAIRYAMVIVSSI 552 A +G I+ E +N P+ + + E+AE G +T L E+A ++ ++ Sbjct: 166 AATQGAKIVSLPECFNSPYG-----TKYFPEYAEKIP-GESTQKLCEVAKECSIYLIGGS 219 Query: 553 LERDEKHSDILWNTAVVISDTGNVIGKHRKNH-----IPRVGDFNESNYYMEGNTGHPVF 717 + E+ + L+NT V G ++ K+RK H +P F ES G++ F Sbjct: 220 IP--EEDAGKLYNTCAVFGPDGTLLAKYRKIHLFDIDVPGKITFQESKTLSPGDS-FSTF 276 Query: 718 AXRYGKIAVXICF 756 Y ++ + IC+ Sbjct: 277 DTPYCRVGLGICY 289 >UniRef50_A1HQ26 Cluster: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; n=1; Thermosinus carboxydivorans Nor1|Rep: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase - Thermosinus carboxydivorans Nor1 Length = 258 Score = 38.7 bits (86), Expect = 0.19 Identities = 37/149 (24%), Positives = 65/149 (43%), Gaps = 1/149 (0%) Frame = +1 Query: 376 GQEGVNIICFQELWNMPFAFCTREKQPWCEFAESAEDGPTTTFLRELAIRY-AMVIVSSI 552 G +++ E+W +A RE W E E G T + + ++ +Y A +I SI Sbjct: 29 GAARADVVVLPEIWTTGYAL--REVDKWAEDVE----GLTISEMSNISRKYGAYIIAGSI 82 Query: 553 LERDEKHSDILWNTAVVISDTGNVIGKHRKNHIPRVGDFNESNYYMEGNTGHPVFAXRYG 732 R K+ + +N AVVI GNV ++RK H+ E ++ G+ F + Sbjct: 83 PLR--KNGKV-YNGAVVIGPDGNVAAEYRKIHL--FSMMGEERFFAAGDR-RCTFNLKGV 136 Query: 733 KIAVXICFGRDHVLNWMMFGXNGXEIVXI 819 + IC+ + + +G +IV + Sbjct: 137 TAGIAICYDLRFPELFRVLALDGAQIVFL 165 >UniRef50_Q4WEA8 Cluster: Hydrolase, carbon-nitrogen family, putative; n=1; Aspergillus fumigatus|Rep: Hydrolase, carbon-nitrogen family, putative - Aspergillus fumigatus (Sartorya fumigata) Length = 321 Score = 38.7 bits (86), Expect = 0.19 Identities = 28/100 (28%), Positives = 47/100 (47%), Gaps = 5/100 (5%) Frame = +1 Query: 535 VIVSSILERDEKHSD-----ILWNTAVVISDTGNVIGKHRKNHIPRVGDFNESNYYMEGN 699 ++ SI+ER E +D L+NTA IS+ G+++G ++K +I + G Sbjct: 109 LVPGSIVERHETEADGKEGFNLYNTAYFISNDGSILGSYQKKNIWHP---ERPHLTSSGE 165 Query: 700 TGHPVFAXRYGKIAVXICFGRDHVLNWMMFGXNGXEIVXI 819 H VF GK+ + IC+ + +G E+V I Sbjct: 166 APHEVFDTPIGKVGLLICWDLAFPEAFRELIASGAEVVII 205 >UniRef50_Q6RWQ0 Cluster: Nitrilase; n=3; uncultured organism|Rep: Nitrilase - uncultured organism Length = 325 Score = 38.3 bits (85), Expect = 0.25 Identities = 32/116 (27%), Positives = 50/116 (43%), Gaps = 14/116 (12%) Frame = +1 Query: 337 AIFNKVKKIIDVAGQEGVNIICFQE----------LWNMPFAFC--TREKQPWCEFAESA 480 A K ++I A + G N+I F E +W A R+K W ++ Sbjct: 24 ATVEKACRLIGEAAENGANLIVFPEAFIPVYPNAAIWGRGLATFGGQRQKYVWTRLWNNS 83 Query: 481 ED--GPTTTFLRELAIRYAMVIVSSILERDEKHSDILWNTAVVISDTGNVIGKHRK 642 + GP T L + A +V + ER ++ L+NT + I G ++GKHRK Sbjct: 84 VEIPGPATDRLAKAAHEARATVVMGLNER-AVDNNTLYNTLLFIGPDGRLLGKHRK 138 >UniRef50_Q8KCC8 Cluster: Carbon-nitrogen hydrolase family protein; n=10; Chlorobiaceae|Rep: Carbon-nitrogen hydrolase family protein - Chlorobium tepidum Length = 286 Score = 38.3 bits (85), Expect = 0.25 Identities = 20/57 (35%), Positives = 29/57 (50%) Frame = +1 Query: 583 LWNTAVVISDTGNVIGKHRKNHIPRVGDFNESNYYMEGNTGHPVFAXRYGKIAVXIC 753 ++N+A + D G HRK ++P G F E Y+ G V + R GK+ V IC Sbjct: 93 VYNSAFMFED-GAGRSVHRKIYLPTYGMFEELRYFSAGRQIETVTSRRIGKVGVAIC 148 >UniRef50_A7DA57 Cluster: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; n=2; Methylobacterium extorquens PA1|Rep: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase - Methylobacterium extorquens PA1 Length = 369 Score = 38.3 bits (85), Expect = 0.25 Identities = 26/91 (28%), Positives = 39/91 (42%), Gaps = 1/91 (1%) Frame = +1 Query: 484 DGPTTTFLRELAIRYAMVIVSSILERDEKHSDILWNTAVVISDTGNVIGKHRKNHIPRVG 663 DGP +R A R+ +++ E E LWN V+I G ++ HRK V Sbjct: 81 DGPEIGAVRAAARRHGVLVSLGFSESTEASVGCLWNANVLIGRDGAILNHHRK----LVP 136 Query: 664 DFNESNYYMEGNT-GHPVFAXRYGKIAVXIC 753 F E + G+ G V G++ + IC Sbjct: 137 TFYEKLIWANGDARGLRVTRTEIGRVGMLIC 167 >UniRef50_A5WCY0 Cluster: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; n=42; Bacteria|Rep: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase - Psychrobacter sp. PRwf-1 Length = 545 Score = 38.3 bits (85), Expect = 0.25 Identities = 33/148 (22%), Positives = 61/148 (41%), Gaps = 4/148 (2%) Frame = +1 Query: 325 EQKKAIFNKVKKIIDVAGQEGVNIICFQELWNMP-FAFCTREKQPWCEFAESAEDGPTTT 501 E + + +V+ +D+ + C E +N P C Q A T Sbjct: 237 ESPEELLQQVEFFVDIMADYNADFACLPEFFNAPLMGLCESTDQ---NIAIRFLADYTEW 293 Query: 502 FLRE---LAIRYAMVIVSSILERDEKHSDILWNTAVVISDTGNVIGKHRKNHIPRVGDFN 672 F E LA+ Y + +++ + +++ ++L+N + + G V + RK HI Sbjct: 294 FKNEISNLAVSYNVNVITGSMPLFDENEEVLYNVSYLCRRDGTV-EEQRKIHIT---PHE 349 Query: 673 ESNYYMEGNTGHPVFAXRYGKIAVXICF 756 S + +EG VF G+I + IC+ Sbjct: 350 RSAWVIEGGNKVQVFDTDAGRIGILICY 377 >UniRef50_A4YP30 Cluster: N-carbamoyl-D-amino acid hydrolase; n=4; Proteobacteria|Rep: N-carbamoyl-D-amino acid hydrolase - Bradyrhizobium sp. (strain ORS278) Length = 332 Score = 38.3 bits (85), Expect = 0.25 Identities = 40/168 (23%), Positives = 72/168 (42%), Gaps = 15/168 (8%) Frame = +1 Query: 361 IIDVAGQEGVNIICFQEL-WNMPFAFCTREKQPWCEFAESAEDGPTTTFLRELA--IRYA 531 +++ A +G ++ F EL + F E+ + E + P+ L + A +R Sbjct: 20 LLEGAAAQGATLVVFPELAFTTFFPRWILERDALDSYFERSMPNPSVAALFDRARELRVG 79 Query: 532 MVIVSSILERDEKHSDILWNTAVVISDTGNVIGKHRKNHI-----PRVG---DFNESNYY 687 + + L D + +N+A+++ G +I K+RK H+ PR G E Y+ Sbjct: 80 FYVGYAELTPDGRR----FNSAILVDADGQLISKYRKVHLPGSVEPREGARYQQLEKRYF 135 Query: 688 MEGNTGHPVF--AXRYGK--IAVXICFGRDHVLNWMMFGXNGXEIVXI 819 G+ G P +G + + IC R +W M G G E+V + Sbjct: 136 GYGDLGFPAVRAGPEWGGAIMGMMICNDRRWPESWRMLGMQGVELVCV 183 >UniRef50_A0LQU6 Cluster: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; n=1; Acidothermus cellulolyticus 11B|Rep: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase - Acidothermus cellulolyticus (strain ATCC 43068 / 11B) Length = 272 Score = 38.3 bits (85), Expect = 0.25 Identities = 32/107 (29%), Positives = 57/107 (53%), Gaps = 5/107 (4%) Frame = +1 Query: 346 NKVKKIID-VAGQEGVNIICFQELWNMPFAFCTREKQPWCEFAESAED--GPTTTFLREL 516 ++V +++D VA +++ ELW +P AF +R FAE A + GP L + Sbjct: 18 DRVDRVVDLVASCRDADLVVLPELW-VPGAFASRF------FAEVATELPGPIIPRLGAV 70 Query: 517 AIRY-AMVIVSSILERDEKHSD-ILWNTAVVISDTGNVIGKHRKNHI 651 A A ++ + +ER + +D I +NTAV+++ G + +RK H+ Sbjct: 71 AKELGAFIMAGTFIERADPATDRIGYNTAVLLNPDGAIAHTYRKVHL 117 >UniRef50_Q9ZMC7 Cluster: Putative; n=6; Campylobacterales|Rep: Putative - Helicobacter pylori J99 (Campylobacter pylori J99) Length = 294 Score = 37.9 bits (84), Expect = 0.33 Identities = 42/171 (24%), Positives = 75/171 (43%), Gaps = 6/171 (3%) Frame = +1 Query: 262 RIVKVGIIQHSIAVPTDRPVNEQKKAIFNKVKKIIDVAGQEGVNIICFQELWNMPFAFCT 441 RI+K +IQ +NE + N K+ A +G N+I EL++ + Sbjct: 9 RILKTAVIQMQ---SKPYALNENLQLALNLAKE----AHNKGANLIVLPELFDSGYCVND 61 Query: 442 REKQPWCEFA--ESAEDGPTTTFLRELAIRYAMVIVSSILERDEKHSDILWNTAVVISDT 615 ++ +F E E+ LR L+ + EK++ L+++A +I Sbjct: 62 KDADFGLDFKAIEHGEETLKNETLRALSDFAKSSDTHIVACSIEKNNKKLYDSAYIIPPK 121 Query: 616 GNVIGKHRKNHIPRVGDFNESNYYMEGNTGHPVFAXRYG----KIAVXICF 756 G ++GKHRK ++ GD E + + G + VF +G K+ + IC+ Sbjct: 122 GKIVGKHRKIYL--WGD--EKSRFKRGKK-YEVFTLDFGDFSAKVGLQICY 167 >UniRef50_A6DBX4 Cluster: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; n=1; Caminibacter mediatlanticus TB-2|Rep: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase - Caminibacter mediatlanticus TB-2 Length = 247 Score = 37.9 bits (84), Expect = 0.33 Identities = 25/91 (27%), Positives = 44/91 (48%) Frame = +1 Query: 481 EDGPTTTFLRELAIRYAMVIVSSILERDEKHSDILWNTAVVISDTGNVIGKHRKNHIPRV 660 ED F R L +V+ ++I +DE ++N+A+ + D+ + +H K H+P Sbjct: 50 EDAFNEEFFRSLKFDKDVVLGAAI--KDEGR---IYNSALYLGDSFH---RHNKVHLPTY 101 Query: 661 GDFNESNYYMEGNTGHPVFAXRYGKIAVXIC 753 G F E ++ G F ++GK + IC Sbjct: 102 GVFEEGRFFFRGK-DFSCFNTKFGKTTIFIC 131 >UniRef50_A0J1U1 Cluster: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; n=1; Shewanella woodyi ATCC 51908|Rep: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase - Shewanella woodyi ATCC 51908 Length = 288 Score = 37.9 bits (84), Expect = 0.33 Identities = 25/86 (29%), Positives = 43/86 (50%) Frame = +1 Query: 487 GPTTTFLRELAIRYAMVIVSSILERDEKHSDILWNTAVVISDTGNVIGKHRKNHIPRVGD 666 G T L ++A + +V+ + E D + ++T+ +IS TGN+IGK+R+ H Sbjct: 66 GECTDKLCQIAKEGGIYLVAGLFEVD---GESYFSTSFLISPTGNIIGKYRRVHC----- 117 Query: 667 FNESNYYMEGNTGHPVFAXRYGKIAV 744 F Y+ + PVF G+I + Sbjct: 118 FEMERKYISQGSDFPVFNTDIGRIGL 143 >UniRef50_A0LH50 Cluster: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; n=1; Syntrophobacter fumaroxidans MPOB|Rep: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase - Syntrophobacter fumaroxidans (strain DSM 10017 / MPOB) Length = 260 Score = 37.5 bits (83), Expect = 0.44 Identities = 29/102 (28%), Positives = 49/102 (48%), Gaps = 1/102 (0%) Frame = +1 Query: 454 PWCEFAESAEDGPTTTF-LRELAIRYAMVIVSSILERDEKHSDILWNTAVVISDTGNVIG 630 P+ E A P +R A R+ MV+V S+ E + ++NT+ VI G + G Sbjct: 51 PYSRLQEVASRTPEVVEEMRGWARRHGMVLVGSLPESVDGR---IYNTSYVIDANGEIAG 107 Query: 631 KHRKNHIPRVGDFNESNYYMEGNTGHPVFAXRYGKIAVXICF 756 +RK H+ + +E ++ G T V + G++ V IC+ Sbjct: 108 SYRKVHLFSL--HHEDLHFGRGETS-LVCSTEAGELGVMICY 146 >UniRef50_Q2QQ94 Cluster: Hydrolase, carbon-nitrogen family protein, expressed; n=4; Magnoliophyta|Rep: Hydrolase, carbon-nitrogen family protein, expressed - Oryza sativa subsp. japonica (Rice) Length = 323 Score = 37.5 bits (83), Expect = 0.44 Identities = 33/133 (24%), Positives = 57/133 (42%), Gaps = 5/133 (3%) Frame = +1 Query: 373 AGQEGVNIICFQELWNMPFAFCTREKQPWCEFAESAEDGPTTTFLRELAIRYAMVIVSSI 552 A GV +CF E+ F+F + + AE DGP LA +M + Sbjct: 73 AASSGVKFLCFPEV----FSFIGSKDGESIKIAEPL-DGPIMQRYCSLAKESSMWLSLGG 127 Query: 553 LERDEKHSDILWNTAVVISDTGNVIGKHRKNH-----IPRVGDFNESNYYMEGNTGHPVF 717 + +NT V+I D+G + +RK H +P + ES + G+T V Sbjct: 128 FQEKGPDDSHQYNTHVLIDDSGEIRSSYRKIHLFDVDVPGNMVYKESRFTTAGDTVVAVD 187 Query: 718 AXRYGKIAVXICF 756 + +G++ + +C+ Sbjct: 188 SP-FGRLGLTVCY 199 >UniRef50_O25836 Cluster: Formamidase; n=17; Bacteria|Rep: Formamidase - Helicobacter pylori (Campylobacter pylori) Length = 334 Score = 37.5 bits (83), Expect = 0.44 Identities = 49/167 (29%), Positives = 73/167 (43%), Gaps = 8/167 (4%) Frame = +1 Query: 277 GIIQHSIAVPTDRPVNEQKKAIFNKVKKIIDV-----AGQEGVNIICFQELWNMPFAFCT 441 G + +I P P+ +K I + ++ II AG GV +I F E ++ Sbjct: 13 GFLVAAIQFPV--PIVNSRKDIDHNIESIIRTLHATKAGYPGVELIIFPE-----YSTQG 65 Query: 442 REKQPWCEFAESAEDGP-TTTFLRELAIRYAMVI-VSSILERDEKHSDILWNTAVVISDT 615 W E D P T L A + A V V SI+ER+ + +NTA++I Sbjct: 66 LNTAKWLS-EEFLLDVPGKETELYAKACKEAKVYGVFSIMERNPDSNKNPYNTAIIIDPQ 124 Query: 616 GNVIGKHRKNHIPRVGDFNESNYYMEGNTGHPVFAXRYG-KIAVXIC 753 G +I K+RK + +N + G+ G PV G K+AV IC Sbjct: 125 GEIILKYRK-----LFPWNPIEPWYPGDLGMPVCEGPGGSKLAVCIC 166 >UniRef50_Q74FF8 Cluster: Hydrolase, carbon-nitrogen family; n=6; Geobacter|Rep: Hydrolase, carbon-nitrogen family - Geobacter sulfurreducens Length = 283 Score = 37.1 bits (82), Expect = 0.58 Identities = 28/91 (30%), Positives = 45/91 (49%), Gaps = 1/91 (1%) Frame = +1 Query: 484 DGPTTTFLRELAIRYAMVIVSSILERDEKHSDI-LWNTAVVISDTGNVIGKHRKNHIPRV 660 D P LREL+ R+ + V + E +D +NT++ + + G V HRK ++P Sbjct: 63 DAPEINALRELS-RHISIAVGLV----EVSADYRFFNTSLYL-EGGEVRHVHRKVYLPTY 116 Query: 661 GDFNESNYYMEGNTGHPVFAXRYGKIAVXIC 753 G F+E Y G F R+G++ + IC Sbjct: 117 GLFDEQRYLARGE-HFRAFDSRFGRMGLLIC 146 >UniRef50_A4YSE7 Cluster: N-carbamoyl-D-amino acid hydrolase; n=11; Proteobacteria|Rep: N-carbamoyl-D-amino acid hydrolase - Bradyrhizobium sp. (strain ORS278) Length = 318 Score = 36.7 bits (81), Expect = 0.77 Identities = 47/200 (23%), Positives = 78/200 (39%), Gaps = 13/200 (6%) Frame = +1 Query: 259 PRIVKVGIIQHSIAVPTDRPVNEQKKAIFNKVKKIIDVAGQEGVNIICFQELWNMPF--A 432 PR V V I Q P R +E + + ++ ++ A G ++I + EL F Sbjct: 2 PRFVNVAIGQLG---PIAR--SEPRSVVVARLIALMRQAHANGCDLIVYPELALTTFFPR 56 Query: 433 FCTREKQPWCEFAESAEDGPTTTFL----RELAIRYAMVIVSSILERDEKHSDILWNTAV 600 + ++ + E GP T L +EL I + + +E H +NTA+ Sbjct: 57 WYMADQAEIDTYFEREMPGPETQALFALTKELRIGFCLGYAELTVEDGVVHR---YNTAI 113 Query: 601 VISDTGNVIGKHRKNHIPRVGDFNE-------SNYYMEGNTGHPVFAXRYGKIAVXICFG 759 ++ ++ K+RK H+P + Y E G V G I + IC Sbjct: 114 LVDKDARIVSKYRKVHLPGHAEHEPWRKFQHLEKRYFEPGRGFGVADAFGGVIGMAICND 173 Query: 760 RDHVLNWMMFGXNGXEIVXI 819 R + + G G E+V I Sbjct: 174 RRWPETYRVMGLQGVEMVLI 193 >UniRef50_Q4Q8W4 Cluster: Nitrilase, putative; n=6; Trypanosomatidae|Rep: Nitrilase, putative - Leishmania major Length = 279 Score = 36.7 bits (81), Expect = 0.77 Identities = 37/152 (24%), Positives = 65/152 (42%), Gaps = 6/152 (3%) Frame = +1 Query: 319 VNEQKKAIFNKVKKIIDVAGQEGVNIICFQELWNMPFAFCTREKQPWCEFAESAEDGPTT 498 V +K A K +I A + G + E +N P+ + + E++E+ G T Sbjct: 14 VTREKAANIKKAVTMITEAAKRGSKLAVLPECFNCPYG-----TKYFDEYSEALAPGNET 68 Query: 499 -TFLRELAIRYAMVIVSSILERDEKHSD-ILWNTAVVISDTGNVIGKHRKNHIPRVGD-- 666 + + A ++ IV+ + EK +D L+N+++ G + HRK H+ + Sbjct: 69 FDAMSQCAKANSIWIVAGSIP--EKSADGKLFNSSMTFGSDGALKHVHRKVHLFCINTDT 126 Query: 667 --FNESNYYMEGNTGHPVFAXRYGKIAVXICF 756 F+ES GN + + K V ICF Sbjct: 127 VRFDESEVLSAGNDATAISLDEHTKFGVAICF 158 >UniRef50_Q23384 Cluster: Putative uncharacterized protein nit-1; n=2; Caenorhabditis|Rep: Putative uncharacterized protein nit-1 - Caenorhabditis elegans Length = 305 Score = 36.7 bits (81), Expect = 0.77 Identities = 45/156 (28%), Positives = 71/156 (45%), Gaps = 14/156 (8%) Frame = +1 Query: 331 KKAIFNKVKKIIDVAGQEGVNIICFQEL-------WN-MPFAFCTREKQPWCEFA---ES 477 K A KVKK ++ A G ++ F E WN TR + EF E+ Sbjct: 16 KPATLEKVKKNVEEAAGNGAELVLFPEAFIGGYPKWNSFGITMGTRTPEGRKEFKRYFEN 75 Query: 478 A--EDGPTTTFLRELAIRYAMVIVSSILERDEKHSDILWNTAVVISDTGNVIGKHRKNHI 651 A E+G + + LA + + IV ++ER+ + L+ + S +G +GKHRK + Sbjct: 76 AIEENGEESKLIESLAAQNNIHIVIGVVERE---ASTLYCSVFFYSPSG-YLGKHRKL-L 130 Query: 652 PRVGDFNESNYYMEGN-TGHPVFAXRYGKIAVXICF 756 P E + +G+ + PVF+ GKI IC+ Sbjct: 131 PTA---LERCVWGQGDGSTMPVFSTSVGKIGSAICW 163 >UniRef50_Q0LC17 Cluster: NAD+ synthetase; n=1; Herpetosiphon aurantiacus ATCC 23779|Rep: NAD+ synthetase - Herpetosiphon aurantiacus ATCC 23779 Length = 622 Score = 36.3 bits (80), Expect = 1.0 Identities = 20/87 (22%), Positives = 41/87 (47%) Frame = +1 Query: 559 RDEKHSDILWNTAVVISDTGNVIGKHRKNHIPRVGDFNESNYYMEGNTGHPVFAXRYGKI 738 R+ ++ L+ T + HRK +P G F+E+ + +E F R+G++ Sbjct: 96 RERFYNSALYATIGSDQSLAGIRHVHRKMFLPTYGVFDEARF-VEAGRQIAAFDTRFGRV 154 Query: 739 AVXICFGRDHVLNWMMFGXNGXEIVXI 819 A+ IC H L+ + +G +++ + Sbjct: 155 AILICEDAWHSLSGTVAALDGAQMLYV 181 >UniRef50_Q04W18 Cluster: Amidohydrolase; n=4; Leptospira|Rep: Amidohydrolase - Leptospira borgpetersenii serovar Hardjo-bovis (strain JB197) Length = 280 Score = 36.3 bits (80), Expect = 1.0 Identities = 22/73 (30%), Positives = 37/73 (50%) Frame = +1 Query: 481 EDGPTTTFLRELAIRYAMVIVSSILERDEKHSDILWNTAVVISDTGNVIGKHRKNHIPRV 660 ++GPT TFL+E+A I ++++ K +NT V+S G +I ++ K H Sbjct: 67 DEGPTETFLKEIAKDAKTTICGGWIQKNPKGKP--FNTVSVVSPKGEIILRYSKIHPFTF 124 Query: 661 GDFNESNYYMEGN 699 G E +Y G+ Sbjct: 125 G--GEDRHYSSGS 135 >UniRef50_Q6RWQ5 Cluster: Nitrilase; n=1; uncultured organism|Rep: Nitrilase - uncultured organism Length = 298 Score = 35.9 bits (79), Expect = 1.3 Identities = 34/134 (25%), Positives = 54/134 (40%), Gaps = 5/134 (3%) Frame = +1 Query: 370 VAGQEGVNIICFQELWNMPFAFCTREKQPWCE--FAESAED--GPTTTFLRELAIRYAMV 537 +A EG I + W FA K E+A D GP L + A R Sbjct: 39 IALPEGFVPIMPRSCWGHHFALIASPKSAALHRRIWENAVDVGGPLARELGDAARRADAW 98 Query: 538 IVSSILERDEKHSDILWNTAVVISDTGNVIGKHRKNHIPRVGDFNESNYYMEG-NTGHPV 714 + + ERD + LWNT + + G++ +HRK V +E ++ +G Sbjct: 99 VAIGVNERDARRPGTLWNTLLWFAPDGSLARRHRK----LVPTMHERTFWGQGAGDDLEA 154 Query: 715 FAXRYGKIAVXICF 756 A +G++ IC+ Sbjct: 155 LAADFGRLGGLICW 168 >UniRef50_Q12DE7 Cluster: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; n=6; Proteobacteria|Rep: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase - Polaromonas sp. (strain JS666 / ATCC BAA-500) Length = 321 Score = 35.5 bits (78), Expect = 1.8 Identities = 44/198 (22%), Positives = 78/198 (39%), Gaps = 11/198 (5%) Frame = +1 Query: 259 PRIVKVGIIQHSIAVPTDRPVNEQKKAIFNKVKKIIDVAGQEGVNIICFQELWNMPF--A 432 PR + V + Q P R N+ + + ++ ++ A G +I + EL F Sbjct: 2 PRYINVALGQLG---PIQR--NDTRAQVVGRLCALMRQAHAVGAQLIVYPELALTTFFPR 56 Query: 433 FCTREKQPWCEFAESAEDGPTTTFLRELAIRYAMVIVSSILE-RDEKHSDILWNTAVVIS 609 + + Q ++ E T L LA + E E +++ +NT++++ Sbjct: 57 WYIEDPQEINQYFEREMPSAATQPLFSLAQELGVGFYLGYAELAQEAGAELRYNTSILVD 116 Query: 610 DTGNVIGKHRKNHIP--------RVGDFNESNYYMEGNTGHPVFAXRYGKIAVXICFGRD 765 G ++ K+RK H+P R E Y+ G G V G + + IC R Sbjct: 117 RFGQIVAKYRKVHLPGHKEHEPWRRFQHLEKRYFTPG-PGFGVTNAFGGVMGMAICNDRR 175 Query: 766 HVLNWMMFGXNGXEIVXI 819 + + G G E+V I Sbjct: 176 WAETYRVMGLQGVEMVLI 193 >UniRef50_A0U0W3 Cluster: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; n=4; Burkholderia cepacia complex|Rep: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase - Burkholderia cenocepacia MC0-3 Length = 275 Score = 35.5 bits (78), Expect = 1.8 Identities = 26/112 (23%), Positives = 52/112 (46%) Frame = +1 Query: 484 DGPTTTFLRELAIRYAMVIVSSILERDEKHSDILWNTAVVISDTGNVIGKHRKNHIPRVG 663 DGP+ + +R A + +V + E+D+ +NTA+++ + G + ++RK+H+ Sbjct: 63 DGPSVSAIRAAARDAHVAVVIGVAEQDDGR---YFNTAILVDEFGELRLRYRKSHLYE-- 117 Query: 664 DFNESNYYMEGNTGHPVFAXRYGKIAVXICFGRDHVLNWMMFGXNGXEIVXI 819 ++ + G T V R K+ + ICF + G E++ I Sbjct: 118 --SDVGVFEAGGT-FDVCEWRGVKVGMLICFDLEFPETARALARAGAELIVI 166 >UniRef50_A0CJZ7 Cluster: Chromosome undetermined scaffold_2, whole genome shotgun sequence; n=2; Oligohymenophorea|Rep: Chromosome undetermined scaffold_2, whole genome shotgun sequence - Paramecium tetraurelia Length = 274 Score = 35.5 bits (78), Expect = 1.8 Identities = 28/111 (25%), Positives = 51/111 (45%), Gaps = 1/111 (0%) Frame = +1 Query: 322 NEQKKAIFNKVK-KIIDVAGQEGVNIICFQELWNMPFAFCTREKQPWCEFAESAEDGPTT 498 N KA N++ + + ++ ++I+ E+ + + + +K F E GPT Sbjct: 17 NYDFKANINRINISLQKYSSKDEIDILVLPEMALIGYYY--PDKNAIKPFLEQYGKGPTY 74 Query: 499 TFLRELAIRYAMVIVSSILERDEKHSDILWNTAVVISDTGNVIGKHRKNHI 651 F +++A R + E D D L+N+AVV++ G I RK H+ Sbjct: 75 EFCKQIAQRLKCYVSCGYAEVD---GDKLYNSAVVVNREGEAILNVRKKHL 122 >UniRef50_Q5K7Z3 Cluster: Expressed protein; n=1; Filobasidiella neoformans|Rep: Expressed protein - Cryptococcus neoformans (Filobasidiella neoformans) Length = 337 Score = 35.5 bits (78), Expect = 1.8 Identities = 23/96 (23%), Positives = 43/96 (44%) Frame = +1 Query: 481 EDGPTTTFLRELAIRYAMVIVSSILERDEKHSDILWNTAVVISDTGNVIGKHRKNHIPRV 660 + GP + + + +A + L +E + I+ NTA I + G + G++ K ++ Sbjct: 122 KSGPRPSKVTLQQLEWAKYLEQHPLSSEENSTPIVKNTAFFIDEEGVLQGEYVKQNLWHP 181 Query: 661 GDFNESNYYMEGNTGHPVFAXRYGKIAVXICFGRDH 768 E Y + G VF ++GK + IC+ H Sbjct: 182 ----EREYIVAGIEPRQVFETKWGKAGLLICWDMSH 213 >UniRef50_Q6RWN7 Cluster: Nitrilase; n=21; root|Rep: Nitrilase - uncultured organism Length = 353 Score = 35.1 bits (77), Expect = 2.3 Identities = 19/47 (40%), Positives = 29/47 (61%), Gaps = 1/47 (2%) Frame = +1 Query: 505 LRELAIRYAMVIVSSILERDEKHSDI-LWNTAVVISDTGNVIGKHRK 642 LR+ A + +V + ER+ + S L+NTA+VI G +IG+HRK Sbjct: 89 LRDAARDGGVTVVIGVNERNTEASGASLYNTALVIGPLGQLIGRHRK 135 >UniRef50_Q4KB18 Cluster: Hydrolase, carbon-nitrogen family; n=2; Bacteria|Rep: Hydrolase, carbon-nitrogen family - Pseudomonas fluorescens (strain Pf-5 / ATCC BAA-477) Length = 325 Score = 35.1 bits (77), Expect = 2.3 Identities = 16/46 (34%), Positives = 25/46 (54%) Frame = +1 Query: 505 LRELAIRYAMVIVSSILERDEKHSDILWNTAVVISDTGNVIGKHRK 642 LRE A ++ +V + ER +H L+N+ V I G ++ HRK Sbjct: 95 LREAARVNSVTVVMGMNERSRRHGGSLYNSLVTIGPEGTILNVHRK 140 >UniRef50_A4M7Y7 Cluster: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; n=1; Petrotoga mobilis SJ95|Rep: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase - Petrotoga mobilis SJ95 Length = 266 Score = 35.1 bits (77), Expect = 2.3 Identities = 40/139 (28%), Positives = 64/139 (46%), Gaps = 2/139 (1%) Frame = +1 Query: 346 NKVKKIIDVAGQEGVNIICFQELWNMPFAFCTREKQPWCEFAESAEDGPTTTF--LRELA 519 NKV KII+ G + N I F EL +AF ++++ E ES DG F +E + Sbjct: 21 NKVMKIIE--GVDS-NFIVFPELAFTGYAFSSKKEVE--ETYESPLDGIGYAFKTFKEFS 75 Query: 520 IRYAMVIVSSILERDEKHSDILWNTAVVISDTGNVIGKHRKNHIPRVGDFNESNYYMEGN 699 + +V +EK+ +N++++I G +RK H+ F E ++ G+ Sbjct: 76 KDTGVSVVYGF---NEKYEGKYYNSSILIKSDGTY-KIYRKTHL----FFREKLFFTPGD 127 Query: 700 TGHPVFAXRYGKIAVXICF 756 TG V + V ICF Sbjct: 128 TGFWVDNINGINVGVAICF 146 >UniRef50_Q7QAW0 Cluster: ENSANGP00000011026; n=2; Culicidae|Rep: ENSANGP00000011026 - Anopheles gambiae str. PEST Length = 278 Score = 35.1 bits (77), Expect = 2.3 Identities = 39/150 (26%), Positives = 64/150 (42%), Gaps = 5/150 (3%) Frame = +1 Query: 328 QKKAIFNKVKKIIDVAGQEGVNIICFQELWNMPFAFCTREKQPWCEFAESAEDGPTTTFL 507 +++ I N + +I A G +I E +N P++ T E + AE G T+ L Sbjct: 19 KQECIANAISQIRQ-AKDRGARLIILPECFNSPYS--TAE---FGRHAEEIPRGETSQAL 72 Query: 508 RELAIRYAMVIVSSILERDEKHSDILWNTAVVISDTGNVIGKHRKNH-----IPRVGDFN 672 ++A + +V E+ L+NT V G ++ K+RK H IP F Sbjct: 73 AKVAAELGVYLVGGTYP--EREGTRLYNTCPVFGPKGELLCKYRKLHLFDMDIPGRCTFQ 130 Query: 673 ESNYYMEGNTGHPVFAXRYGKIAVXICFGR 762 ES G+ F+ KI + IC+ + Sbjct: 131 ESAALTAGDR-LATFSIGSLKIGLGICWDK 159 >UniRef50_Q83AQ3 Cluster: Putative uncharacterized protein; n=5; Gammaproteobacteria|Rep: Putative uncharacterized protein - Coxiella burnetii Length = 388 Score = 34.7 bits (76), Expect = 3.1 Identities = 24/84 (28%), Positives = 42/84 (50%), Gaps = 7/84 (8%) Frame = -2 Query: 423 HIPQLLETDDVNTLLAGNIDDLLDFIENCFLLLVDWTIGGH------RD-GMLNYSYLHN 265 H P+ E++ VN LL G I L D ++ +LL+D+ H RD G + Y H+ Sbjct: 219 HFPEGYESE-VNLLLKGWIASLADILQEGLILLIDYGFPRHEYYHTDRDRGTIACHYRHH 277 Query: 264 SRRSGLLVLGRESVCGDVEVSLLS 193 S L++ G + + V+ + ++ Sbjct: 278 SHFDPLILTGIQDITAHVDFTAIA 301 >UniRef50_Q2RL06 Cluster: NAD+ synthetase; n=1; Moorella thermoacetica ATCC 39073|Rep: NAD+ synthetase - Moorella thermoacetica (strain ATCC 39073) Length = 577 Score = 34.7 bits (76), Expect = 3.1 Identities = 32/135 (23%), Positives = 60/135 (44%) Frame = +1 Query: 349 KVKKIIDVAGQEGVNIICFQELWNMPFAFCTREKQPWCEFAESAEDGPTTTFLRELAIRY 528 K+++ + A Q G ++ F EL + R+ +F E E + L+ Sbjct: 21 KIRQAVAEARQHGAGLVIFPEL--AVTGYPPRDLLCRHDFLERVERALAED-IAPLSRET 77 Query: 529 AMVIVSSILERDEKHSDILWNTAVVISDTGNVIGKHRKNHIPRVGDFNESNYYMEGNTGH 708 A++I + + R + L+N A++ S G + G+ K+ +P F+ES Y+ Sbjct: 78 AIIIGAPV--RGRGNPAFLYNAALLYSG-GELCGRQDKSLLPNYDVFDESRYFKPATRRL 134 Query: 709 PVFAXRYGKIAVXIC 753 PVF ++ + IC Sbjct: 135 PVFLEGL-RLGLTIC 148 >UniRef50_Q18UU7 Cluster: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; n=2; Desulfitobacterium hafniense|Rep: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase - Desulfitobacterium hafniense (strain DCB-2) Length = 289 Score = 34.7 bits (76), Expect = 3.1 Identities = 30/136 (22%), Positives = 63/136 (46%) Frame = +1 Query: 349 KVKKIIDVAGQEGVNIICFQELWNMPFAFCTREKQPWCEFAESAEDGPTTTFLRELAIRY 528 ++ + +VA +GV+++C+ E A + E A+ D LRE A Sbjct: 25 EIIRTAEVASSQGVSLLCYPEC-----ALHGYSPKDASEIADPL-DSMAVARLRECARDL 78 Query: 529 AMVIVSSILERDEKHSDILWNTAVVISDTGNVIGKHRKNHIPRVGDFNESNYYMEGNTGH 708 ++++ ++E+ + + +V D + +RK H+ R+ E +Y+ G++ Sbjct: 79 GLILLVGMVEKSPEGKKPYISQLIVFPDREPEV--YRKVHLGRI----EQHYFTAGDS-F 131 Query: 709 PVFAXRYGKIAVXICF 756 P+FA K ++ IC+ Sbjct: 132 PIFAAGGVKFSIGICW 147 >UniRef50_Q0EPQ3 Cluster: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase precursor; n=1; Thermoanaerobacter ethanolicus X514|Rep: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase precursor - Thermoanaerobacter ethanolicus X514 Length = 360 Score = 34.7 bits (76), Expect = 3.1 Identities = 25/102 (24%), Positives = 46/102 (45%) Frame = +1 Query: 514 LAIRYAMVIVSSILERDEKHSDILWNTAVVISDTGNVIGKHRKNHIPRVGDFNESNYYME 693 LA +Y + I + +E + L+N ++S G ++G+ +K H+ DF E Sbjct: 144 LAKKYGIYIYTGSYIINENGN--LYNGGALVSREGKILGRQKKIHLT---DFEEKIGLKR 198 Query: 694 GNTGHPVFAXRYGKIAVXICFGRDHVLNWMMFGXNGXEIVXI 819 N +F+ GK+A +C + + + G EIV + Sbjct: 199 ENELE-IFSLDIGKVACPVCMDATYFETFKIASQKGAEIVIL 239 >UniRef50_Q9X0Y0 Cluster: Probable glutamine-dependent NAD(+) synthetase (EC 6.3.5.1) (NAD(+) synthase [glutamine-hydrolyzing]); n=6; Bacteria|Rep: Probable glutamine-dependent NAD(+) synthetase (EC 6.3.5.1) (NAD(+) synthase [glutamine-hydrolyzing]) - Thermotoga maritima Length = 576 Score = 34.7 bits (76), Expect = 3.1 Identities = 19/58 (32%), Positives = 30/58 (51%), Gaps = 2/58 (3%) Frame = +1 Query: 586 WNTAVVISDTGNVIGKHRKNHIPRVGDFNESNYYMEGNTGHPVFAXRYG--KIAVXIC 753 +N A V+ D G ++G +RK +P G F+E Y+ G + + G K+ V IC Sbjct: 95 YNAAAVVKD-GEILGVYRKISLPNYGVFDERRYF---KPGEELLVVKIGNIKVGVTIC 148 >UniRef50_Q3A713 Cluster: Predicted amidohydrolase family protein; n=1; Pelobacter carbinolicus DSM 2380|Rep: Predicted amidohydrolase family protein - Pelobacter carbinolicus (strain DSM 2380 / Gra Bd 1) Length = 262 Score = 34.3 bits (75), Expect = 4.1 Identities = 34/136 (25%), Positives = 55/136 (40%) Frame = +1 Query: 346 NKVKKIIDVAGQEGVNIICFQELWNMPFAFCTREKQPWCEFAESAEDGPTTTFLRELAIR 525 N + K ++ A + G + EL ++F W E + P L + A Sbjct: 28 NLLIKGMEAAAKLGAQWVLTPELCICGYSFADAIGTGWIE----PQPDPWMAQLCQKAAA 83 Query: 526 YAMVIVSSILERDEKHSDILWNTAVVISDTGNVIGKHRKNHIPRVGDFNESNYYMEGNTG 705 M + ER E S +L+N+ +S+ G V+G+HRK + R G + G Sbjct: 84 LHMTLFLGQPER-EPQSGVLFNSVFAVSE-GRVVGRHRKINALRKG---AEAWSTPGTRA 138 Query: 706 HPVFAXRYGKIAVXIC 753 P GK+ + IC Sbjct: 139 TPFPVPPVGKVGLMIC 154 >UniRef50_Q2ADS5 Cluster: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; n=1; Halothermothrix orenii H 168|Rep: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase - Halothermothrix orenii H 168 Length = 349 Score = 34.3 bits (75), Expect = 4.1 Identities = 19/79 (24%), Positives = 39/79 (49%) Frame = +1 Query: 583 LWNTAVVISDTGNVIGKHRKNHIPRVGDFNESNYYMEGNTGHPVFAXRYGKIAVXICFGR 762 L+N + + G +IG+ KNH+ + E+++ ++ VF+ +GK+A+ IC Sbjct: 166 LYNISYLFDPDGTLIGEQTKNHLLPL----EADWGVKPGNKINVFSTDFGKVAIPICMDA 221 Query: 763 DHVLNWMMFGXNGXEIVXI 819 + + + G +V I Sbjct: 222 TYFETFRIAWQKGAHLVTI 240 >UniRef50_Q1IIQ6 Cluster: Sigma-24, ECF subfamily; n=1; Acidobacteria bacterium Ellin345|Rep: Sigma-24, ECF subfamily - Acidobacteria bacterium (strain Ellin345) Length = 226 Score = 34.3 bits (75), Expect = 4.1 Identities = 15/55 (27%), Positives = 31/55 (56%) Frame = -3 Query: 566 SSLSNIEDTITIAYLMASSRRKVVVGPSSADSANSHHGCFSLVQNAKGIFHNSWK 402 +SL+ ++D + YL RK+++G SA+ N+ HG ++ A + H+ ++ Sbjct: 44 NSLTVVDDLVQETYLKICRERKIILGQFSAEHPNAFHGYLKVI--ASNLVHDYFR 96 >UniRef50_A6FX13 Cluster: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; n=1; Plesiocystis pacifica SIR-1|Rep: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase - Plesiocystis pacifica SIR-1 Length = 347 Score = 34.3 bits (75), Expect = 4.1 Identities = 18/54 (33%), Positives = 29/54 (53%), Gaps = 1/54 (1%) Frame = +1 Query: 484 DGPTTTFLRELAIRYAMVIVSSILERD-EKHSDILWNTAVVISDTGNVIGKHRK 642 DGP + E + R + +V ++E E+HS + + TAV I ++G HRK Sbjct: 69 DGPQLRAIAERSRRRGVAVVLGVVEASPERHSSV-YCTAVTIDPARGIVGAHRK 121 >UniRef50_Q7QKM8 Cluster: ENSANGP00000017134; n=5; Culicidae|Rep: ENSANGP00000017134 - Anopheles gambiae str. PEST Length = 281 Score = 34.3 bits (75), Expect = 4.1 Identities = 29/119 (24%), Positives = 51/119 (42%) Frame = +1 Query: 295 IAVPTDRPVNEQKKAIFNKVKKIIDVAGQEGVNIICFQELWNMPFAFCTREKQPWCEFAE 474 IA+ R V+ ++K + N + I ++ N++ E +N P+ T AE Sbjct: 9 IALIQLRVVDSKEKNLKNAIDLIRIAKKEKDANVVVLPECFNAPYTADTL-----LNVAE 63 Query: 475 SAEDGPTTTFLRELAIRYAMVIVSSILERDEKHSDILWNTAVVISDTGNVIGKHRKNHI 651 G T L A + + +V + E S L+NT V G+++ +RK H+ Sbjct: 64 EIPTGETCRALSNAARDFGVHVVGGSIV--ESCSGRLYNTCTVWGPEGDLVATYRKVHL 120 >UniRef50_A2R283 Cluster: Contig An13c0120, complete genome; n=2; Aspergillus|Rep: Contig An13c0120, complete genome - Aspergillus niger Length = 598 Score = 34.3 bits (75), Expect = 4.1 Identities = 39/179 (21%), Positives = 72/179 (40%), Gaps = 18/179 (10%) Frame = +1 Query: 331 KKAIFNKVKKIIDVAGQEGVNIICFQELWNMPF-----AFCTREKQPWCEFAESAEDGPT 495 ++ N++ ++ A +G ++ F E+ F E + W E + P Sbjct: 21 REETLNRMITLLKDAATQGAKLVLFPEIAFTTFFPRYLILDEAELEDWFEHGDILT-APR 79 Query: 496 TTFLRELAIRYAMVIVSSILERDEKHSDILWNTAVVI-SDTGNVIGKHRKNHI------- 651 T L + A A+ I+ E + +N+ V + TG+++ K+RK H+ Sbjct: 80 TKALFDTAHDLAVDIIVGFAEATDTGDH--FNSCVYYHAATGSILSKYRKVHLPGDVEPL 137 Query: 652 --PRVGDFNESNYYMEGNTGHPVFAXR---YGKIAVXICFGRDHVLNWMMFGXNGXEIV 813 P+ + E Y+ G+ G F + + + IC R +W +G G EIV Sbjct: 138 PDPKAVNQLEKRYFKPGDLGFQAFREKDVVDPILGMMICNDRRWAESWREYGLQGVEIV 196 >UniRef50_Q4JAH2 Cluster: Conserved protein; n=4; Sulfolobaceae|Rep: Conserved protein - Sulfolobus acidocaldarius Length = 297 Score = 34.3 bits (75), Expect = 4.1 Identities = 28/108 (25%), Positives = 52/108 (48%), Gaps = 4/108 (3%) Frame = +1 Query: 331 KKAIFNKVKKIIDVAGQEGVNIICFQELWNMP--FAFCTREKQPWCEFAESAEDGPTTTF 504 +KA K +++I VA ++G ++ L+ + F EK+ AE P + Sbjct: 15 RKANIEKARRLIKVAKEKGAKLVVLPSLFPIGNLFEVYENEKKSRSVIRNLAEKIPGS-- 72 Query: 505 LRELAIRYAMVIVSSILERD--EKHSDILWNTAVVISDTGNVIGKHRK 642 + E+ I AM ++ E+ ++ T+++IS G +IGK+RK Sbjct: 73 ISEMLINLAMEGEVHLMAGPILEQAGPKIFLTSLIISPQGEIIGKYRK 120 >UniRef50_Q86X76 Cluster: Nitrilase homolog 1; n=29; Eumetazoa|Rep: Nitrilase homolog 1 - Homo sapiens (Human) Length = 327 Score = 34.3 bits (75), Expect = 4.1 Identities = 20/71 (28%), Positives = 35/71 (49%), Gaps = 5/71 (7%) Frame = +1 Query: 559 RDEKHSDILWNTAVVISDTGNVIGKHRKNH-----IPRVGDFNESNYYMEGNTGHPVFAX 723 +D + + ++N V+++ G V+ +RK H IP G ESN M G + + Sbjct: 134 QDWEQTQKIYNCHVLLNSKGAVVATYRKTHLCDVEIPGQGPMCESNSTMPGPSLESPVST 193 Query: 724 RYGKIAVXICF 756 GKI + +C+ Sbjct: 194 PAGKIGLAVCY 204 >UniRef50_Q9ADI8 Cluster: NAD(+) synthase; n=12; Bacteria|Rep: NAD(+) synthase - Streptomyces coelicolor Length = 613 Score = 33.9 bits (74), Expect = 5.4 Identities = 20/55 (36%), Positives = 29/55 (52%) Frame = +1 Query: 589 NTAVVISDTGNVIGKHRKNHIPRVGDFNESNYYMEGNTGHPVFAXRYGKIAVXIC 753 N A V+ G V K+H+P G F+E Y++ G+T PV R +A+ IC Sbjct: 134 NAAAVLYG-GEVALSFAKHHLPNYGVFDEFRYFVPGDT-LPVVRVRGVDVALAIC 186 >UniRef50_A1SE99 Cluster: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; n=4; Actinomycetales|Rep: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase - Nocardioides sp. (strain BAA-499 / JS614) Length = 280 Score = 33.9 bits (74), Expect = 5.4 Identities = 35/120 (29%), Positives = 58/120 (48%), Gaps = 9/120 (7%) Frame = +1 Query: 334 KAIFNKVKKIIDVAGQEG-VNIICFQELW-NMPFAFCTREKQPWCEFAESAEDGPTTTFL 507 +++ ++V+++ + G +++ ELW + FA T W AE +GPT + Sbjct: 25 ESLSDRVQRVSQWIREVGPADLVVLPELWAHGGFASTT-----WRATAELM-NGPTIAQM 78 Query: 508 RELAIRYAMVI-VSSILERDEKHSDI------LWNTAVVISDTGNVIGKHRKNHIPRVGD 666 +A + + SI+ER E +D LWNT+V+IS G V +RK H GD Sbjct: 79 ASVAREVGVWLHAGSIIERAEDGADRGAERRGLWNTSVLISPQGTVHKTYRKIHRFGFGD 138 >UniRef50_A2D8H0 Cluster: Putative uncharacterized protein; n=1; Trichomonas vaginalis G3|Rep: Putative uncharacterized protein - Trichomonas vaginalis G3 Length = 156 Score = 33.9 bits (74), Expect = 5.4 Identities = 20/64 (31%), Positives = 31/64 (48%), Gaps = 1/64 (1%) Frame = +1 Query: 238 KDEQTRPPRIVKVGIIQHSIAVPTDRPVNE-QKKAIFNKVKKIIDVAGQEGVNIICFQEL 414 K+EQ + + + G+I HS P E KK FN+ I+V+ + V I+ Q Sbjct: 50 KEEQPKKKQTYEEGMINHSTQANVSEPTKELYKKQKFNEYFSHIEVSTFQNVPIMSIQSQ 109 Query: 415 WNMP 426 N+P Sbjct: 110 LNVP 113 >UniRef50_Q2GWJ9 Cluster: Putative uncharacterized protein; n=1; Chaetomium globosum|Rep: Putative uncharacterized protein - Chaetomium globosum (Soil fungus) Length = 1646 Score = 33.9 bits (74), Expect = 5.4 Identities = 19/46 (41%), Positives = 23/46 (50%) Frame = +1 Query: 304 PTDRPVNEQKKAIFNKVKKIIDVAGQEGVNIICFQELWNMPFAFCT 441 PT RP E+ K F ++KI A Q G+ I E WN FA T Sbjct: 20 PTYRPTEEEWKEPFEYIRKISPEARQYGICKIIPPESWNPDFAIDT 65 >UniRef50_Q8TPH6 Cluster: Putative uncharacterized protein; n=1; Methanosarcina acetivorans|Rep: Putative uncharacterized protein - Methanosarcina acetivorans Length = 1078 Score = 33.9 bits (74), Expect = 5.4 Identities = 18/51 (35%), Positives = 30/51 (58%), Gaps = 1/51 (1%) Frame = +1 Query: 265 IVKVGIIQHSIAVPTDRPVNE-QKKAIFNKVKKIIDVAGQEGVNIICFQEL 414 IV++G Q + + P K+A +KV K++D+A +E V+I+C EL Sbjct: 785 IVRIGTAQINFELSESFPPEIIDKEATRDKVFKVLDIATKEKVDIVCLSEL 835 >UniRef50_A5UTD2 Cluster: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase precursor; n=2; Roseiflexus|Rep: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase precursor - Roseiflexus sp. RS-1 Length = 509 Score = 33.5 bits (73), Expect = 7.2 Identities = 29/106 (27%), Positives = 51/106 (48%) Frame = +1 Query: 454 PWCEFAESAEDGPTTTFLRELAIRYAMVIVSSILERDEKHSDILWNTAVVISDTGNVIGK 633 P EFA+ A+D + LA +V ++ R S+ + + AV+ GN +G+ Sbjct: 290 PENEFAD-ADDPAFAAQVGALARELNAYLVVDMVWRT---SEGMHDAAVLFGPDGNEVGR 345 Query: 634 HRKNHIPRVGDFNESNYYMEGNTGHPVFAXRYGKIAVXICFGRDHV 771 H K ++ GD ++ ++ G VF YG + + +C+ R HV Sbjct: 346 HAKINL--TGD-EQAFGFVPGPRDFQVFTTPYGNVGLGVCWDR-HV 387 >UniRef50_Q9LE50 Cluster: Nitrilase 1 like protein; n=2; Arabidopsis thaliana|Rep: Nitrilase 1 like protein - Arabidopsis thaliana (Mouse-ear cress) Length = 316 Score = 33.5 bits (73), Expect = 7.2 Identities = 39/146 (26%), Positives = 65/146 (44%), Gaps = 8/146 (5%) Frame = +1 Query: 343 FNKVKKIIDVAGQEGVNIICFQELWNMPFAFCTREKQPWCEFAESAEDGPTTTFLRELAI 522 F +++ A G +ICF E F+F ++ + AE DGP LA Sbjct: 54 FATCSRLVQEAALAGAKLICFPE----NFSFVGDKEGESVKIAEPL-DGPVMERYCSLA- 107 Query: 523 RYAMVIVS--SILER-DEKHSDILWNTAVVISDTGNVIGKHRKNH-----IPRVGDFNES 678 R + + +S ER D+ H L NT VVI D G + ++K H +P + ES Sbjct: 108 RDSNIWLSLGGFQERFDDTH---LCNTHVVIDDAGMIRDTYQKMHLFDVDVPGGSSYKES 164 Query: 679 NYYMEGNTGHPVFAXRYGKIAVXICF 756 ++ + G V + G++ + +C+ Sbjct: 165 SFTVPGTKIVSVDSP-VGRLGLTVCY 189 >UniRef50_Q17CS4 Cluster: Nitrilase, putative; n=3; Culicidae|Rep: Nitrilase, putative - Aedes aegypti (Yellowfever mosquito) Length = 477 Score = 33.5 bits (73), Expect = 7.2 Identities = 23/78 (29%), Positives = 38/78 (48%), Gaps = 8/78 (10%) Frame = +1 Query: 547 SILERDEKHS--DI--LWNTAVVISDTGNVIGKHRKNHIPRV----GDFNESNYYMEGNT 702 SI E D K D+ ++NT +VI + G ++ ++RK H+ V F ES G+ Sbjct: 119 SIAESDSKSKTGDVQNIYNTHIVIDNEGQLVAQYRKLHMFNVVTPEFKFRESETVRSGSE 178 Query: 703 GHPVFAXRYGKIAVXICF 756 P G++ + IC+ Sbjct: 179 LVPPIETPIGRVGLQICY 196 >UniRef50_A0D532 Cluster: Chromosome undetermined scaffold_38, whole genome shotgun sequence; n=3; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_38, whole genome shotgun sequence - Paramecium tetraurelia Length = 2039 Score = 33.5 bits (73), Expect = 7.2 Identities = 17/55 (30%), Positives = 32/55 (58%), Gaps = 2/55 (3%) Frame = +1 Query: 265 IVKVGIIQHSIAVPTDRPVNEQKKAIFNKVKKIIDVAGQEG--VNIICFQELWNM 423 +VK+ +++ + + + + K IFN++KKI+ V EG + +I F LWN+ Sbjct: 295 VVKLDFLRNYSLEESVKVIKKTKSNIFNQIKKILLVDQIEGQKIEMIGFDRLWNL 349 >UniRef50_Q0UT99 Cluster: Putative uncharacterized protein; n=1; Phaeosphaeria nodorum|Rep: Putative uncharacterized protein - Phaeosphaeria nodorum (Septoria nodorum) Length = 1269 Score = 33.5 bits (73), Expect = 7.2 Identities = 28/84 (33%), Positives = 41/84 (48%) Frame = -2 Query: 471 GKLAPRLLLPCAEREGHIPQLLETDDVNTLLAGNIDDLLDFIENCFLLLVDWTIGGHRDG 292 G+LA R L REG L+ ++ L +I L+D EN LL + I R Sbjct: 1035 GRLAQRPALQAVLREG-FENLIHHRVIDPALMIDILTLMDSGENESLLQSNEFIYAIRVL 1093 Query: 291 MLNYSYLHNSRRSGLLVLGRESVC 220 M+N+ +H + R GLL L + +C Sbjct: 1094 MINWHDIHKTTRDGLLKLVWKRLC 1117 >UniRef50_Q9V206 Cluster: Putative uncharacterized protein; n=1; Pyrococcus abyssi|Rep: Putative uncharacterized protein - Pyrococcus abyssi Length = 213 Score = 33.5 bits (73), Expect = 7.2 Identities = 13/40 (32%), Positives = 22/40 (55%) Frame = +1 Query: 580 ILWNTAVVISDTGNVIGKHRKNHIPRVGDFNESNYYMEGN 699 I+WN +V++D G ++G H + N +N+ EGN Sbjct: 165 IVWNVTLVVNDNGKLVGGHFIGKSIGPSNVNTANWVQEGN 204 >UniRef50_Q1FPL1 Cluster: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; n=2; Bacteria|Rep: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase - Clostridium phytofermentans ISDg Length = 318 Score = 33.1 bits (72), Expect = 9.5 Identities = 29/128 (22%), Positives = 56/128 (43%) Frame = +1 Query: 436 CTREKQPWCEFAESAEDGPTTTFLRELAIRYAMVIVSSILERDEKHSDILWNTAVVISDT 615 C ++K+ + E+ A D + ++++ + + +L K N+A+VI Sbjct: 81 CIKQKKSYQEWVNQAVD-EESDYVKQFCSVAKELHIGIVLTAYTKGIQKPRNSAMVIDKN 139 Query: 616 GNVIGKHRKNHIPRVGDFNESNYYMEGNTGHPVFAXRYGKIAVXICFGRDHVLNWMMFGX 795 GN+I + K H DF+ + +E V K+ V IC+ R++ + M Sbjct: 140 GNIIMTYSKVH---TCDFSLESL-VESGEEFKVCDFHGIKLGVMICYDREYPESARMLML 195 Query: 796 NGXEIVXI 819 G EI+ + Sbjct: 196 KGAEIIVV 203 >UniRef50_A0J1T6 Cluster: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; n=1; Shewanella woodyi ATCC 51908|Rep: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase - Shewanella woodyi ATCC 51908 Length = 279 Score = 33.1 bits (72), Expect = 9.5 Identities = 31/118 (26%), Positives = 58/118 (49%), Gaps = 1/118 (0%) Frame = +1 Query: 292 SIAVPTDRPVNEQKKAIFNKVKKIIDVAGQEGVNIICFQELWNMPFAFCTREKQPWC-EF 468 +IAV R + + + KV +I A +G N IC +P F T P + Sbjct: 10 NIAVIQYRIMQDDMEDNLQKVATLITAAKSKGANFIC------LPANFATGINFPSLRQN 63 Query: 469 AESAEDGPTTTFLRELAIRYAMVIVSSILERDEKHSDILWNTAVVISDTGNVIGKHRK 642 ++S D +FL + A+ + + I + +LE + DI +++A++I G ++ K+R+ Sbjct: 64 SQSLHD--IQSFLSKQALEHEIQICAGVLEWN--GGDI-YDSAILIGSDGQLLAKYRR 116 >UniRef50_Q8IIP2 Cluster: Putative uncharacterized protein; n=1; Plasmodium falciparum 3D7|Rep: Putative uncharacterized protein - Plasmodium falciparum (isolate 3D7) Length = 2371 Score = 33.1 bits (72), Expect = 9.5 Identities = 18/49 (36%), Positives = 29/49 (59%), Gaps = 2/49 (4%) Frame = +1 Query: 43 SLAIMENETHSL--ESIINNNLTGRDLEEFNRIHFGRRNNLEIKLKESS 183 +L++ ENE SL ES+ NNN ++++E IH + E+ +KE S Sbjct: 1149 NLSLSENEESSLIIESLDNNNQETKEMKELEEIHIDSMDE-EVNIKEKS 1196 >UniRef50_Q6XUA7 Cluster: Neuraminidase; n=3339; root|Rep: Neuraminidase - Influenza A virus (strain A/Korea/426/1968 H2N2) Length = 469 Score = 33.1 bits (72), Expect = 9.5 Identities = 10/34 (29%), Positives = 19/34 (55%) Frame = -3 Query: 812 TISXPXCPNIIQFKTWSRPKQXFTAILPYLXANT 711 TI CP +++++ WS+P+ T P+ N+ Sbjct: 72 TIEKEICPEVVEYRNWSKPQCQITGFAPFSKDNS 105 Database: uniref50 Posted date: Oct 5, 2007 11:19 AM Number of letters in database: 575,637,011 Number of sequences in database: 1,657,284 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.279 0.0580 0.190 Matrix: BLOSUM62 Gap Penalties: Existence: 9, Extension: 2 Number of Hits to DB: 808,979,575 Number of Sequences: 1657284 Number of extensions: 16755019 Number of successful extensions: 49048 Number of sequences better than 10.0: 156 Number of HSP's better than 10.0 without gapping: 47072 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 49000 length of database: 575,637,011 effective HSP length: 100 effective length of database: 409,908,611 effective search space used: 77882636090 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 37 (14.9 bits) X3: 62 (25.0 bits) S1: 41 (21.7 bits)
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