BLASTX 2.2.12 [Aug-07-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= BmNP01_FL5_G19 (814 letters) Database: uniref50 1,657,284 sequences; 575,637,011 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value UniRef50_UPI0000D55EDD Cluster: PREDICTED: similar to CG11822-PA... 87 7e-16 UniRef50_Q2XWK6 Cluster: Nicotinic acetylcholine receptor subuni... 77 4e-13 UniRef50_Q4S3I4 Cluster: Chromosome 1 SCAF14749, whole genome sh... 76 1e-12 UniRef50_A7RFJ5 Cluster: Predicted protein; n=2; Nematostella ve... 75 3e-12 UniRef50_Q4S3I6 Cluster: Chromosome 1 SCAF14749, whole genome sh... 73 7e-12 UniRef50_Q2XWK8 Cluster: Nicotinic acetylcholine receptor subuni... 71 5e-11 UniRef50_UPI00015A3E3C Cluster: Neuronal acetylcholine receptor ... 69 1e-10 UniRef50_Q7T2R4 Cluster: Nicotinic acetylcholine receptor alpha ... 69 2e-10 UniRef50_Q17BK7 Cluster: Nicotinic acetylcholine receptor, beta-... 69 2e-10 UniRef50_P48182 Cluster: Acetylcholine receptor subunit beta-typ... 69 2e-10 UniRef50_P30532 Cluster: Neuronal acetylcholine receptor subunit... 68 3e-10 UniRef50_Q4S864 Cluster: Chromosome 5 SCAF14709, whole genome sh... 67 4e-10 UniRef50_Q27218 Cluster: Acetylcholine receptor subunit beta-typ... 67 4e-10 UniRef50_P91766 Cluster: Acetylcholine receptor subunit alpha-li... 67 4e-10 UniRef50_Q60KR8 Cluster: Putative uncharacterized protein CBG239... 67 6e-10 UniRef50_Q5BW84 Cluster: SJCHGC08361 protein; n=1; Schistosoma j... 67 6e-10 UniRef50_UPI0000EBE733 Cluster: PREDICTED: similar to nicotinic ... 66 8e-10 UniRef50_UPI0000E49401 Cluster: PREDICTED: similar to alpha 10 s... 66 8e-10 UniRef50_Q2XWL1 Cluster: Nicotinic acetylcholine receptor subuni... 66 8e-10 UniRef50_A7S3F7 Cluster: Predicted protein; n=1; Nematostella ve... 66 8e-10 UniRef50_Q4RRI3 Cluster: Chromosome 16 SCAF15002, whole genome s... 66 1e-09 UniRef50_O44497 Cluster: Putative uncharacterized protein; n=2; ... 66 1e-09 UniRef50_P17787 Cluster: Neuronal acetylcholine receptor subunit... 66 1e-09 UniRef50_P17644 Cluster: Acetylcholine receptor subunit alpha-li... 66 1e-09 UniRef50_Q4RIA9 Cluster: Chromosome 8 SCAF15044, whole genome sh... 66 1e-09 UniRef50_P43681 Cluster: Neuronal acetylcholine receptor subunit... 66 1e-09 UniRef50_UPI00015B4A35 Cluster: PREDICTED: similar to nicotinic ... 65 2e-09 UniRef50_Q66T35 Cluster: Nicotinic acetylcholine receptor subuni... 64 3e-09 UniRef50_A7RHV9 Cluster: Predicted protein; n=3; Nematostella ve... 64 3e-09 UniRef50_A0EIZ7 Cluster: Nicotinic acetylcholine receptor alpha9... 64 3e-09 UniRef50_Q04844 Cluster: Acetylcholine receptor subunit epsilon ... 64 3e-09 UniRef50_P11230 Cluster: Acetylcholine receptor subunit beta pre... 64 3e-09 UniRef50_UPI0001560C7D Cluster: PREDICTED: similar to cholinergi... 64 4e-09 UniRef50_Q4SXG5 Cluster: Chromosome undetermined SCAF12416, whol... 64 4e-09 UniRef50_A7T134 Cluster: Predicted protein; n=1; Nematostella ve... 64 4e-09 UniRef50_P04755 Cluster: Acetylcholine receptor subunit beta-lik... 64 4e-09 UniRef50_Q93329 Cluster: Putative uncharacterized protein lev-8;... 64 5e-09 UniRef50_Q0GQR6 Cluster: GABA-gated ion channel; n=2; Apis melli... 64 5e-09 UniRef50_Q15822 Cluster: Neuronal acetylcholine receptor subunit... 64 5e-09 UniRef50_Q8JFN7 Cluster: Neuronal acetylcholine receptor subunit... 64 5e-09 UniRef50_UPI00015B5C4C Cluster: PREDICTED: similar to GABA-gated... 63 7e-09 UniRef50_UPI0000E47D8F Cluster: PREDICTED: similar to nicotinic ... 63 7e-09 UniRef50_UPI0000E47C59 Cluster: PREDICTED: similar to alpha-9 ni... 63 7e-09 UniRef50_Q4S866 Cluster: Chromosome 5 SCAF14709, whole genome sh... 63 7e-09 UniRef50_Q9N4M3 Cluster: Acetylcholine receptor protein 6; n=1; ... 63 7e-09 UniRef50_Q24352 Cluster: Gamma-aminobutyric acid receptor alpha-... 63 7e-09 UniRef50_Q9GP98 Cluster: Acetylcholine receptor protein 22; n=3;... 63 9e-09 UniRef50_Q2XWK5 Cluster: Nicotinic acetylcholine receptor subuni... 63 9e-09 UniRef50_Q8WSF7 Cluster: GABA A receptor alpha subunit; n=1; Apl... 62 1e-08 UniRef50_Q66T21 Cluster: Nicotinic acetylcholine receptor subuni... 62 1e-08 UniRef50_A7RLP3 Cluster: Predicted protein; n=3; Nematostella ve... 62 1e-08 UniRef50_A2TM48 Cluster: Nicotinic acetylcholine receptor alpha ... 62 1e-08 UniRef50_Q2XWL0 Cluster: Nicotinic acetylcholine receptor subuni... 62 2e-08 UniRef50_P48180 Cluster: Acetylcholine receptor subunit alpha-ty... 62 2e-08 UniRef50_A7UFK6 Cluster: Nicotinic acetylcholine receptor alpha ... 62 2e-08 UniRef50_P54245 Cluster: Uncharacterized acetylcholine receptor-... 62 2e-08 UniRef50_Q9U298 Cluster: Neuronal acetylcholine receptor subunit... 62 2e-08 UniRef50_A7S622 Cluster: Predicted protein; n=1; Nematostella ve... 61 3e-08 UniRef50_UPI0000E49402 Cluster: PREDICTED: similar to alpha 10 s... 61 4e-08 UniRef50_O16926 Cluster: Acetylcholine receptor protein 15; n=2;... 61 4e-08 UniRef50_Q9UGM1 Cluster: Neuronal acetylcholine receptor subunit... 61 4e-08 UniRef50_UPI00015B4DDF Cluster: PREDICTED: similar to neurotrans... 60 5e-08 UniRef50_Q7T2S3 Cluster: Nicotinic acetylcholine receptor alpha ... 60 5e-08 UniRef50_A7RLM4 Cluster: Predicted protein; n=2; Nematostella ve... 60 5e-08 UniRef50_P07510 Cluster: Acetylcholine receptor subunit gamma pr... 60 5e-08 UniRef50_UPI0000E49844 Cluster: PREDICTED: similar to nicotinic ... 60 7e-08 UniRef50_UPI0000E47C58 Cluster: PREDICTED: similar to nicotinic ... 60 7e-08 UniRef50_Q23022 Cluster: Acetylcholine receptor subunit alpha-ty... 60 7e-08 UniRef50_Q2XWK3 Cluster: Nicotinic acetylcholine receptor subuni... 60 9e-08 UniRef50_Q65XS8 Cluster: Acetylcholine receptor protein 25; n=2;... 59 1e-07 UniRef50_A7SI11 Cluster: Predicted protein; n=1; Nematostella ve... 59 1e-07 UniRef50_UPI0000E464AB Cluster: PREDICTED: similar to nicotinic ... 59 2e-07 UniRef50_Q7Z6B2 Cluster: 5-hydroxytryptamine serotonin receptor ... 59 2e-07 UniRef50_Q23355 Cluster: Putative uncharacterized protein acr-8;... 58 2e-07 UniRef50_O46132 Cluster: Nicotinic acetylcholine receptor, alpha... 58 3e-07 UniRef50_P25162 Cluster: Acetylcholine receptor subunit beta-lik... 58 3e-07 UniRef50_UPI00015B5C6B Cluster: PREDICTED: similar to nicotinic ... 58 3e-07 UniRef50_Q9GQ00 Cluster: Serotonin-gated chloride channel; n=4; ... 58 3e-07 UniRef50_Q29ND1 Cluster: GA17977-PA; n=3; Schizophora|Rep: GA179... 58 3e-07 UniRef50_A7SW63 Cluster: Predicted protein; n=3; Nematostella ve... 58 3e-07 UniRef50_A7RK99 Cluster: Predicted protein; n=2; Nematostella ve... 58 3e-07 UniRef50_UPI0000E48B7E Cluster: PREDICTED: similar to neuronal n... 57 5e-07 UniRef50_A0EIZ9 Cluster: Nicotinic acetylcholine receptor beta2 ... 57 5e-07 UniRef50_Q60S81 Cluster: Neuronal acetylcholine receptor subunit... 57 5e-07 UniRef50_UPI0000D55E50 Cluster: PREDICTED: similar to AcetylChol... 57 6e-07 UniRef50_A7SNK1 Cluster: Predicted protein; n=2; Nematostella ve... 57 6e-07 UniRef50_A7RUG1 Cluster: Predicted protein; n=2; Nematostella ve... 57 6e-07 UniRef50_P91197 Cluster: Acetylcholine receptor protein 11; n=2;... 56 8e-07 UniRef50_O62083 Cluster: Putative uncharacterized protein acr-19... 56 8e-07 UniRef50_A5H038 Cluster: Nicotinic acetylcholine receptor subuni... 56 8e-07 UniRef50_Q7KT97 Cluster: CG32975-PB, isoform B; n=69; Eumetazoa|... 56 1e-06 UniRef50_Q17BK9 Cluster: Nicotinic acetylcholine receptor, putat... 56 1e-06 UniRef50_A7S9T6 Cluster: Predicted protein; n=2; Nematostella ve... 56 1e-06 UniRef50_A6QL44 Cluster: Nicotinic acetylcholine receptor non-al... 56 1e-06 UniRef50_Q10052 Cluster: Gaba/glycine receptor family (See gbr) ... 56 1e-06 UniRef50_O17848 Cluster: Putative uncharacterized protein acr-18... 56 1e-06 UniRef50_A7RNI2 Cluster: Predicted protein; n=3; Nematostella ve... 56 1e-06 UniRef50_O61519 Cluster: Ligand-gated ion channel protein 6; n=4... 55 2e-06 UniRef50_A7RS33 Cluster: Predicted protein; n=1; Nematostella ve... 55 2e-06 UniRef50_Q4RZC6 Cluster: Chromosome 1 SCAF14944, whole genome sh... 55 2e-06 UniRef50_UPI0000E4930A Cluster: PREDICTED: similar to nicotinic ... 54 3e-06 UniRef50_UPI0000E47621 Cluster: PREDICTED: similar to nicotinic ... 54 3e-06 UniRef50_Q9XTY8 Cluster: Putative uncharacterized protein lgc-25... 54 3e-06 UniRef50_Q9N5U8 Cluster: Acetylcholine receptor protein 21; n=2;... 54 3e-06 UniRef50_Q2XWL2 Cluster: Nicotinic acetylcholine receptor subuni... 54 3e-06 UniRef50_Q07001 Cluster: Acetylcholine receptor subunit delta pr... 54 3e-06 UniRef50_UPI0000ECB6ED Cluster: Acetylcholine receptor subunit a... 54 4e-06 UniRef50_Q67X94 Cluster: Putative uncharacterized protein lgc-2;... 54 4e-06 UniRef50_A7RS32 Cluster: Predicted protein; n=1; Nematostella ve... 54 4e-06 UniRef50_P18505 Cluster: Gamma-aminobutyric acid receptor subuni... 54 4e-06 UniRef50_P31644 Cluster: Gamma-aminobutyric acid receptor subuni... 54 4e-06 UniRef50_UPI0000D56893 Cluster: PREDICTED: similar to CG6698-PA;... 54 6e-06 UniRef50_UPI000058896A Cluster: PREDICTED: similar to cholinergi... 54 6e-06 UniRef50_Q7PJX0 Cluster: ENSANGP00000022703; n=1; Anopheles gamb... 54 6e-06 UniRef50_Q4R170 Cluster: Putative uncharacterized protein; n=1; ... 54 6e-06 UniRef50_Q18556 Cluster: Putative uncharacterized protein acr-9;... 54 6e-06 UniRef50_O18228 Cluster: Putative uncharacterized protein lgc-7;... 54 6e-06 UniRef50_UPI00006A0B5C Cluster: Gamma-aminobutyric-acid receptor... 53 7e-06 UniRef50_Q2XWK9 Cluster: Nicotinic acetylcholine receptor subuni... 53 7e-06 UniRef50_Q2XWK4 Cluster: Nicotinic acetylcholine receptor subuni... 53 7e-06 UniRef50_Q21645 Cluster: Acetylcholine receptor protein 10; n=2;... 53 7e-06 UniRef50_A7S2J7 Cluster: Predicted protein; n=1; Nematostella ve... 53 7e-06 UniRef50_UPI0000F2C37E Cluster: PREDICTED: similar to CHRNG prot... 53 1e-05 UniRef50_UPI00015A4976 Cluster: 5-hydroxytryptamine receptor 3 s... 53 1e-05 UniRef50_Q6TMY0 Cluster: Nicotinic acetylcholine receptor non-al... 53 1e-05 UniRef50_Q0GQQ6 Cluster: Cys-loop ligand-gated ion channel subun... 53 1e-05 UniRef50_Q4V4V5 Cluster: IP12579p; n=6; Endopterygota|Rep: IP125... 52 1e-05 UniRef50_Q19351 Cluster: Ligand-gated ion channel protein 3; n=3... 52 1e-05 UniRef50_Q86YW4 Cluster: Ligand-gated ion channel subunit; n=10;... 52 1e-05 UniRef50_Q6Q069 Cluster: Neuronal nicotinic acetylcholine Apisa7... 52 2e-05 UniRef50_Q6F6K3 Cluster: Acetylcholine receptor protein 17, isof... 52 2e-05 UniRef50_Q2XWK7 Cluster: Nicotinic acetylcholine receptor subuni... 52 2e-05 UniRef50_A7S2N9 Cluster: Predicted protein; n=3; Nematostella ve... 52 2e-05 UniRef50_UPI0000586C99 Cluster: PREDICTED: similar to nicotinic ... 52 2e-05 UniRef50_Q22224 Cluster: Putative uncharacterized protein acr-14... 52 2e-05 UniRef50_P36544 Cluster: Neuronal acetylcholine receptor subunit... 52 2e-05 UniRef50_UPI00015B6212 Cluster: PREDICTED: similar to nicotinic ... 51 3e-05 UniRef50_Q6TMY3 Cluster: Nicotinic acetylcholine receptor alpha ... 51 3e-05 UniRef50_A7SLK4 Cluster: Predicted protein; n=2; Nematostella ve... 51 3e-05 UniRef50_A7RFJ2 Cluster: Predicted protein; n=1; Nematostella ve... 51 3e-05 UniRef50_UPI0000E48474 Cluster: PREDICTED: similar to nicotinic ... 51 4e-05 UniRef50_UPI0000E47329 Cluster: PREDICTED: similar to novel chol... 51 4e-05 UniRef50_Q9GQU9 Cluster: Nicotinic acetylcholine receptor-like s... 51 4e-05 UniRef50_UPI0000E473D1 Cluster: PREDICTED: similar to neuronal a... 50 5e-05 UniRef50_Q9VPQ8 Cluster: CG11822-PA, isoform A (Nicotinic acetyl... 50 5e-05 UniRef50_A7S2P0 Cluster: Predicted protein; n=4; Nematostella ve... 50 5e-05 UniRef50_P34903 Cluster: Gamma-aminobutyric acid receptor subuni... 50 5e-05 UniRef50_Q621V5 Cluster: Putative uncharacterized protein CBG023... 50 7e-05 UniRef50_A7RR86 Cluster: Predicted protein; n=1; Nematostella ve... 50 7e-05 UniRef50_P02708 Cluster: Acetylcholine receptor subunit alpha pr... 50 7e-05 UniRef50_Q4RR58 Cluster: Chromosome 14 SCAF15003, whole genome s... 50 9e-05 UniRef50_A7RND6 Cluster: Predicted protein; n=1; Nematostella ve... 50 9e-05 UniRef50_UPI000069FF34 Cluster: UPI000069FF34 related cluster; n... 49 1e-04 UniRef50_Q9W288 Cluster: CG6698-PA; n=4; Sophophora|Rep: CG6698-... 49 1e-04 UniRef50_Q14DU4 Cluster: CHRNG protein; n=3; Euarchontoglires|Re... 49 1e-04 UniRef50_Q99928 Cluster: Gamma-aminobutyric acid receptor subuni... 49 1e-04 UniRef50_UPI000069F132 Cluster: 5-hydroxytryptamine receptor 3 s... 49 2e-04 UniRef50_UPI00006602DC Cluster: Homolog of Homo sapiens "5-hydro... 49 2e-04 UniRef50_O44452 Cluster: Putative uncharacterized protein; n=2; ... 49 2e-04 UniRef50_A7S6R3 Cluster: Predicted protein; n=3; Nematostella ve... 49 2e-04 UniRef50_P41849 Cluster: Uncharacterized glycine receptor-like p... 49 2e-04 UniRef50_O18276 Cluster: Gamma-aminobutyric acid receptor subuni... 49 2e-04 UniRef50_A7S9T8 Cluster: Predicted protein; n=1; Nematostella ve... 48 2e-04 UniRef50_A6XBS1 Cluster: Amorphous calcium carbonate binding pro... 48 2e-04 UniRef50_UPI0000E47720 Cluster: PREDICTED: similar to alpha-9 ni... 48 3e-04 UniRef50_UPI00003CEF8B Cluster: R03E1.3; n=1; Caenorhabditis ele... 48 3e-04 UniRef50_Q9GUF0 Cluster: Ligand-gated ion channel protein 10; n=... 48 3e-04 UniRef50_Q6BET0 Cluster: Putative uncharacterized protein; n=2; ... 48 3e-04 UniRef50_P48169 Cluster: Gamma-aminobutyric acid receptor subuni... 48 3e-04 UniRef50_UPI0000E20C28 Cluster: PREDICTED: gamma-aminobutyric ac... 48 4e-04 UniRef50_A2TM50 Cluster: Nicotinic acetylcholine receptor alpha ... 48 4e-04 UniRef50_Q4RN70 Cluster: Chromosome undetermined SCAF15016, whol... 47 5e-04 UniRef50_Q95Y52 Cluster: Putative uncharacterized protein; n=2; ... 47 5e-04 UniRef50_A7S2G2 Cluster: Predicted protein; n=2; Nematostella ve... 47 5e-04 UniRef50_A7RLM5 Cluster: Predicted protein; n=1; Nematostella ve... 47 5e-04 UniRef50_P45963 Cluster: Acetylcholine receptor subunit alpha-ty... 47 5e-04 UniRef50_P46098 Cluster: 5-hydroxytryptamine receptor 3 precurso... 47 5e-04 UniRef50_Q4RLA7 Cluster: Chromosome 21 SCAF15022, whole genome s... 47 6e-04 UniRef50_Q20828 Cluster: Putative uncharacterized protein; n=2; ... 47 6e-04 UniRef50_Q9UN88 Cluster: Gamma-aminobutyric acid receptor subuni... 47 6e-04 UniRef50_O00591 Cluster: Gamma-aminobutyric acid receptor subuni... 47 6e-04 UniRef50_UPI0000F1DA85 Cluster: PREDICTED: similar to MGC52789 p... 46 9e-04 UniRef50_UPI0000EB6CC4 Cluster: glycine receptor, beta b; n=1; D... 46 0.001 UniRef50_UPI000065F0EC Cluster: Homolog of Homo sapiens "5-hydro... 46 0.001 UniRef50_UPI0000660F16 Cluster: Homolog of Homo sapiens "Splice ... 46 0.002 UniRef50_Q4S0E0 Cluster: Chromosome 2 SCAF14781, whole genome sh... 46 0.002 UniRef50_Q7NDN8 Cluster: Glr4197 protein; n=1; Gloeobacter viola... 46 0.002 UniRef50_Q8TA51 Cluster: Putative uncharacterized protein; n=3; ... 46 0.002 UniRef50_A7RTF8 Cluster: Predicted protein; n=1; Nematostella ve... 46 0.002 UniRef50_A7T7Z5 Cluster: Predicted protein; n=1; Nematostella ve... 45 0.002 UniRef50_A7SDE9 Cluster: Predicted protein; n=1; Nematostella ve... 45 0.002 UniRef50_UPI0000F1E62D Cluster: PREDICTED: hypothetical protein;... 45 0.003 UniRef50_UPI0000E49D12 Cluster: PREDICTED: similar to acetylchol... 45 0.003 UniRef50_UPI000058727F Cluster: PREDICTED: similar to Chain B, R... 45 0.003 UniRef50_UPI00006A0062 Cluster: UPI00006A0062 related cluster; n... 45 0.003 UniRef50_A7SVS1 Cluster: Predicted protein; n=5; Nematostella ve... 45 0.003 UniRef50_A7S8Q4 Cluster: Predicted protein; n=3; Nematostella ve... 45 0.003 UniRef50_O75311 Cluster: Glycine receptor subunit alpha-3 precur... 45 0.003 UniRef50_O14764 Cluster: Gamma-aminobutyric acid receptor subuni... 45 0.003 UniRef50_Q6U4B6 Cluster: Nicotinic acetylcholine receptor alpha ... 44 0.003 UniRef50_Q22085 Cluster: Putative uncharacterized protein lgc-17... 44 0.003 UniRef50_A4FTX5 Cluster: CHRNB4 protein; n=1; Homo sapiens|Rep: ... 44 0.003 UniRef50_UPI0000E45D33 Cluster: PREDICTED: similar to nicotinic ... 44 0.005 UniRef50_Q7ZTN5 Cluster: MGC52789 protein; n=1; Xenopus laevis|R... 44 0.005 UniRef50_Q4BXY7 Cluster: Neurotransmitter-gated ion-channel liga... 44 0.005 UniRef50_Q61I41 Cluster: Putative uncharacterized protein CBG104... 44 0.005 UniRef50_Q2WF65 Cluster: Gaba/glycine receptor family (See gbr) ... 44 0.005 UniRef50_UPI00015B60A2 Cluster: PREDICTED: similar to nicotinic ... 44 0.006 UniRef50_Q4SRT2 Cluster: Chromosome undetermined SCAF14492, whol... 44 0.006 UniRef50_A2BGE6 Cluster: Glycine receptor, alpha 4b; n=5; Danio ... 44 0.006 UniRef50_Q93323 Cluster: Putative uncharacterized protein lgc-21... 44 0.006 UniRef50_Q4W520 Cluster: Putative uncharacterized protein; n=1; ... 44 0.006 UniRef50_P25123 Cluster: Gamma-aminobutyric acid receptor subuni... 44 0.006 UniRef50_UPI0000E4906A Cluster: PREDICTED: similar to nicotinic ... 43 0.008 UniRef50_Q4RU50 Cluster: Chromosome 1 SCAF14995, whole genome sh... 43 0.008 UniRef50_O16426 Cluster: Ligand-gated ion channel protein 1; n=2... 43 0.011 UniRef50_P34271 Cluster: Acetylcholine receptor-like protein cup... 43 0.011 UniRef50_Q9NA62 Cluster: Putative uncharacterized protein; n=1; ... 42 0.014 UniRef50_A7SRB3 Cluster: Predicted protein; n=3; Nematostella ve... 42 0.014 UniRef50_A7S8M2 Cluster: Predicted protein; n=2; Nematostella ve... 42 0.014 UniRef50_UPI0000E47589 Cluster: PREDICTED: similar to gamma-amin... 42 0.018 UniRef50_Q4SRT3 Cluster: Chromosome undetermined SCAF14492, whol... 42 0.018 UniRef50_Q4SC79 Cluster: Chromosome undetermined SCAF14659, whol... 42 0.018 UniRef50_Q8MM20 Cluster: Putative uncharacterized protein; n=3; ... 42 0.018 UniRef50_A7SDF1 Cluster: Predicted protein; n=2; Nematostella ve... 42 0.018 UniRef50_A7RTX5 Cluster: Predicted protein; n=1; Nematostella ve... 42 0.024 UniRef50_UPI00015B4D8A Cluster: PREDICTED: similar to glutamate-... 41 0.032 UniRef50_UPI0000E4929C Cluster: PREDICTED: similar to nicotinic ... 41 0.032 UniRef50_Q4SJX0 Cluster: Chromosome 1 SCAF14573, whole genome sh... 41 0.032 UniRef50_Q7PTU5 Cluster: ENSANGP00000015420; n=2; Anopheles gamb... 41 0.032 UniRef50_Q6U4B7 Cluster: Nicotinic acetylcholine receptor alpha ... 41 0.032 UniRef50_Q6U4B5 Cluster: Nicotinic acetylcholine receptor beta 1... 41 0.032 UniRef50_A7SN20 Cluster: Predicted protein; n=1; Nematostella ve... 41 0.032 UniRef50_UPI0000584BCE Cluster: PREDICTED: hypothetical protein;... 41 0.043 UniRef50_UPI000065DFE4 Cluster: 5-hydroxytryptamine 3 receptor p... 41 0.043 UniRef50_A4TVG5 Cluster: Glycine receptor, alpha 4 subunit; n=1;... 41 0.043 UniRef50_O97141 Cluster: Nicotinic acetylcholine beta subunit ho... 41 0.043 UniRef50_Q2PMX5 Cluster: GABA receptor; n=1; Tetranychus urticae... 40 0.056 UniRef50_A7SDF0 Cluster: Predicted protein; n=2; Nematostella ve... 40 0.075 UniRef50_P54244 Cluster: Acetylcholine receptor subunit alpha-ty... 40 0.075 UniRef50_Q9U358 Cluster: Putative uncharacterized protein acc-4;... 40 0.099 UniRef50_Q9TVI7 Cluster: Putative uncharacterized protein; n=2; ... 40 0.099 UniRef50_Q61KY4 Cluster: Putative uncharacterized protein CBG091... 33 0.11 UniRef50_Q9XTE5 Cluster: Putative uncharacterized protein lgc-31... 39 0.13 UniRef50_O61884 Cluster: Acetylcholine receptor protein 23; n=2;... 39 0.13 UniRef50_A7RNN1 Cluster: Predicted protein; n=2; Nematostella ve... 39 0.13 UniRef50_A7RF65 Cluster: Predicted protein; n=1; Nematostella ve... 39 0.13 UniRef50_UPI00015B58ED Cluster: PREDICTED: similar to GABA-gated... 39 0.17 UniRef50_Q60NW3 Cluster: Putative uncharacterized protein CBG225... 39 0.17 UniRef50_O01792 Cluster: Putative uncharacterized protein; n=2; ... 39 0.17 UniRef50_Q94900 Cluster: Glutamate-gated chloride channel precur... 39 0.17 UniRef50_Q61R47 Cluster: Putative uncharacterized protein CBG067... 38 0.23 UniRef50_A7RT31 Cluster: Predicted protein; n=1; Nematostella ve... 38 0.23 UniRef50_O17402 Cluster: Putative uncharacterized protein; n=2; ... 38 0.30 UniRef50_Q4SXG4 Cluster: Chromosome undetermined SCAF12416, whol... 38 0.40 UniRef50_Q21005 Cluster: Putative uncharacterized protein acc-1;... 38 0.40 UniRef50_A7SFG6 Cluster: Predicted protein; n=4; Nematostella ve... 38 0.40 UniRef50_A7S2G5 Cluster: Predicted protein; n=1; Nematostella ve... 38 0.40 UniRef50_Q8WSF8 Cluster: Soluble acetylcholine receptor; n=2; Ap... 37 0.53 UniRef50_Q6QWI5 Cluster: Acetylcholine receptor 20 (63.9 kD) alt... 37 0.53 UniRef50_A7SQS7 Cluster: Predicted protein; n=1; Nematostella ve... 37 0.53 UniRef50_P58154 Cluster: Acetylcholine-binding protein precursor... 37 0.53 UniRef50_Q4SGK0 Cluster: Chromosome 3 SCAF14593, whole genome sh... 37 0.70 UniRef50_Q9VGI0 Cluster: CG14723-PA, isoform A; n=12; Endopteryg... 37 0.70 UniRef50_A7SCG0 Cluster: Predicted protein; n=1; Nematostella ve... 36 0.92 UniRef50_Q0GQQ7 Cluster: PH-sensitive chloride channel variant 4... 36 1.2 UniRef50_UPI000051DDF1 Cluster: ACETYLCHOLINE-BINDING PROTEIN; n... 36 1.6 UniRef50_Q08861 Cluster: Gamma-aminobutyric acid-grated chloride... 36 1.6 UniRef50_UPI0000E48167 Cluster: PREDICTED: similar to nicotinic ... 35 2.1 UniRef50_UPI0000E4771F Cluster: PREDICTED: hypothetical protein;... 35 2.1 UniRef50_Q5WN65 Cluster: Putative uncharacterized protein CBG081... 35 2.1 UniRef50_UPI0000E81668 Cluster: PREDICTED: similar to Probable p... 35 2.8 UniRef50_UPI0000E46711 Cluster: PREDICTED: similar to Neuronal a... 35 2.8 UniRef50_Q3JT18 Cluster: Flavoprotein reductase; n=2; Burkholder... 35 2.8 UniRef50_Q21420 Cluster: Putative uncharacterized protein; n=4; ... 35 2.8 UniRef50_A7RTF6 Cluster: Predicted protein; n=2; Nematostella ve... 35 2.8 UniRef50_UPI0000E46D49 Cluster: PREDICTED: similar to nicotinic ... 34 4.9 UniRef50_Q8EKA6 Cluster: Fibronectin type III domain protein; n=... 34 4.9 UniRef50_Q7NHR7 Cluster: Gll2468 protein; n=1; Gloeobacter viola... 34 4.9 UniRef50_Q7YTP9 Cluster: Putative uncharacterized protein; n=2; ... 34 4.9 UniRef50_A7SH22 Cluster: Predicted protein; n=1; Nematostella ve... 34 4.9 UniRef50_UPI0001560B17 Cluster: PREDICTED: similar to precursor ... 33 6.5 UniRef50_UPI0000DB7771 Cluster: PREDICTED: similar to nicotinic ... 33 6.5 UniRef50_UPI000041A8E7 Cluster: PREDICTED: similar to Gamma-amin... 33 6.5 UniRef50_A7S5Y7 Cluster: Predicted protein; n=1; Nematostella ve... 33 6.5 UniRef50_UPI0000E4906F Cluster: PREDICTED: similar to nicotinic ... 33 8.6 UniRef50_Q4STL8 Cluster: Chromosome undetermined SCAF14147, whol... 33 8.6 UniRef50_Q9W4G1 Cluster: CG6927-PA; n=6; Diptera|Rep: CG6927-PA ... 33 8.6 UniRef50_Q9VDU9 Cluster: CG7411-PA; n=12; Endopterygota|Rep: CG7... 33 8.6 UniRef50_Q9V9Y4 Cluster: CG11340-PA; n=2; Sophophora|Rep: CG1134... 33 8.6 UniRef50_P91985 Cluster: Putative uncharacterized protein; n=1; ... 33 8.6 >UniRef50_UPI0000D55EDD Cluster: PREDICTED: similar to CG11822-PA, isoform A; n=1; Tribolium castaneum|Rep: PREDICTED: similar to CG11822-PA, isoform A - Tribolium castaneum Length = 438 Score = 86.6 bits (205), Expect = 7e-16 Identities = 50/184 (27%), Positives = 93/184 (50%), Gaps = 11/184 (5%) Frame = +2 Query: 116 NATSLSLMIDSLLATYDRESPP-----DSKIVVNLTLHLRHANIRESESTVRILADLQMN 280 N+T + LL YD+ + P +K+V LT+ RH + E +ST+ + + ++++ Sbjct: 36 NSTVTDKLRQDLLLNYDKFARPAQHYNTTKVVFGLTI--RHIELNEFKSTLVVHSWIRLS 93 Query: 281 WIDKRLSWSAGEWG-CSTWLVSSERLWRPDVVLLNAAATTAGDYA--LRARVSNNGSVSW 451 W D++L W++ +G T ++ +W+PD+ L N+A ++ + + V G V W Sbjct: 94 WKDEKLQWNSTNYGGLETLNLADHEIWQPDIFLYNSATSSGITHYGNVNCIVYEGGDVLW 153 Query: 452 IKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDK---RIYSMFESXAWDV 622 + S ++ L WP D Q C FGS +N D++D D ++ + E+ W++ Sbjct: 154 VPPAQFSVLCNLNLKYWPFDTQRCEMIFGSWTYNGDQIDIDPDNDGVKMELLIENSEWNI 213 Query: 623 TDLS 634 D S Sbjct: 214 VDKS 217 >UniRef50_Q2XWK6 Cluster: Nicotinic acetylcholine receptor subunit type G; n=1; Lymnaea stagnalis|Rep: Nicotinic acetylcholine receptor subunit type G - Lymnaea stagnalis (Great pond snail) Length = 618 Score = 77.4 bits (182), Expect = 4e-13 Identities = 48/152 (31%), Positives = 79/152 (51%), Gaps = 7/152 (4%) Frame = +2 Query: 134 LMIDSLLATYDRESPP--DSKIVVNLTLHLRHANIRESESTVRILAD---LQMNWIDKRL 298 L+++ LLA Y R S P ++ + V + L I + + ++L L+ W+D+RL Sbjct: 90 LLMERLLARYHRYSRPVMNASLSVQVKFGLTLVQISDMDEVNQVLTINVWLEQEWVDERL 149 Query: 299 SWSAGEWGCSTWL-VSSERLWRPDVVLLNAAAT-TAGDYALRARVSNNGSVSWIKRLDIS 472 +WS E+ L + E+LW PD+VL N+A T G +A V +NG+V W Sbjct: 150 TWSPKEYNNLHILRIPCEKLWLPDIVLYNSADDYTTGYMNSKAMVQHNGTVFWPPPAKFR 209 Query: 473 TPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 568 + + + +P D QTC KFGS ++ ++D Sbjct: 210 SSCKIDITYFPFDDQTCELKFGSWTYDGFQVD 241 >UniRef50_Q4S3I4 Cluster: Chromosome 1 SCAF14749, whole genome shotgun sequence; n=2; Euteleostomi|Rep: Chromosome 1 SCAF14749, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 503 Score = 75.8 bits (178), Expect = 1e-12 Identities = 42/129 (32%), Positives = 67/129 (51%), Gaps = 5/129 (3%) Frame = +2 Query: 269 LQMNWIDKRLSWSAGEWGCSTWL-VSSERLWRPDVVLL-NAAATTAGDYALRARVSNNGS 442 L WID +L W+ ++G T + V SE LW PD+VL NA G +A V NG+ Sbjct: 64 LCQEWIDYKLRWNPDKYGGITSIRVPSENLWLPDIVLYENADGRFEGSLMTKAIVRYNGA 123 Query: 443 VSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFV-IDKRI--YSMFESXA 613 ++W + +M + +P D Q CT KFGS ++ +D + IDK++ F++ Sbjct: 124 ITWTPPASYKSACTMDVTFFPFDRQNCTMKFGSWTYDGTMVDLILIDKQVDRKDFFDNGE 183 Query: 614 WDVTDLSXA 640 W++ + A Sbjct: 184 WEILSATGA 192 >UniRef50_A7RFJ5 Cluster: Predicted protein; n=2; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 328 Score = 74.5 bits (175), Expect = 3e-12 Identities = 48/179 (26%), Positives = 90/179 (50%), Gaps = 12/179 (6%) Frame = +2 Query: 134 LMIDSLLATYDRESPP--DSKIVVNLTLHL-RHANIRESESTVRILADLQMNWIDKRLSW 304 +++ L YDR+ P ++ +VV L R A + E + V L+ W++ LSW Sbjct: 8 ILLRYLFTNYDRDIHPGGNNPVVVTFGAKLGRIAAVDEKNNVVLAHWYLKQKWVNPSLSW 67 Query: 305 SAGEWG-CSTWLVSSERLWRPDVVLLNAAATT---AGDYALRARVSN--NGSVSWIKRLD 466 +A E+G +T V +RLW PD+VL N A AG + + ++ +G++ W+ Sbjct: 68 NASEFGGVNTLHVEPDRLWVPDIVLYNNADPKNDLAGGFQYKTKIEMQADGTMIWLAPAM 127 Query: 467 ISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVID---KRIYSMFESXAWDVTDLS 634 + M + +P D Q+C +F S M+++ +++ ID ++ F + W++ L+ Sbjct: 128 FHSACPMDIRYFPFDEQSCDLQFASWMYDTSKLEMKIDANETKVMDTFTNKEWEIPKLT 186 >UniRef50_Q4S3I6 Cluster: Chromosome 1 SCAF14749, whole genome shotgun sequence; n=1; Tetraodon nigroviridis|Rep: Chromosome 1 SCAF14749, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 340 Score = 73.3 bits (172), Expect = 7e-12 Identities = 54/191 (28%), Positives = 86/191 (45%), Gaps = 9/191 (4%) Frame = +2 Query: 86 CAIASAAECENATSLSLMIDSLLATYDRESPPDSK---IVVNLTL-HLRHANIRESESTV 253 C AS AE E L+ R + +S+ I + ++L L H N R+ T Sbjct: 1 CTAASCAEVEERLVSHLLAPDRYNKLIRPAVNNSQQVTIYIQVSLAQLIHVNERDQIMTT 60 Query: 254 RILADLQMNWIDKRLSWSAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARV 427 L W D RL W+ E+ G + ++ +W PD+VL N A T Y A + Sbjct: 61 NCW--LSQVWYDYRLMWNPEEYEGIKKIRLPTQHIWLPDIVLYNNADGTYEVSYYSNAVI 118 Query: 428 SNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDKRIYSMFE- 604 SNNG V+W+ + +++ ++P D Q CT +F S ++ E+D ++ S + Sbjct: 119 SNNGEVNWLPPAIYKSACKIEVRDFPFDQQNCTLQFRSWTYDHTEIDLILVSDYASRDDF 178 Query: 605 --SXAWDVTDL 631 S WD+ L Sbjct: 179 KPSGEWDIVSL 189 >UniRef50_Q2XWK8 Cluster: Nicotinic acetylcholine receptor subunit type E; n=16; Protostomia|Rep: Nicotinic acetylcholine receptor subunit type E - Lymnaea stagnalis (Great pond snail) Length = 538 Score = 70.5 bits (165), Expect = 5e-11 Identities = 44/135 (32%), Positives = 70/135 (51%), Gaps = 6/135 (4%) Frame = +2 Query: 188 KIVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWSAGEWGCSTWL-VSSERLWR 361 K+VV + + L +I E + L+ W DK+L+W A E+G L V SE +W Sbjct: 56 KLVVKMGIRLSQLIDIDEKNQIMTTNVWLRQEWTDKKLTWQASEYGGVDHLYVPSEHIWL 115 Query: 362 PDVVLLNAAATTAGDYAL----RARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTF 529 PD+VL N A G+Y + +A V + G V W + ++ ++ +P D Q+C Sbjct: 116 PDIVLYNNAD---GNYEVTLMTKATVHSTGLVVWEPPAIYKSSCTINVEFFPFDEQSCKM 172 Query: 530 KFGSRMHNSDEMDFV 574 KFGS ++ D++D V Sbjct: 173 KFGSWTYDGDQVDLV 187 >UniRef50_UPI00015A3E3C Cluster: Neuronal acetylcholine receptor subunit alpha-4 precursor.; n=1; Danio rerio|Rep: Neuronal acetylcholine receptor subunit alpha-4 precursor. - Danio rerio Length = 556 Score = 69.3 bits (162), Expect = 1e-10 Identities = 48/187 (25%), Positives = 96/187 (51%), Gaps = 15/187 (8%) Frame = +2 Query: 110 CENATSLSLMIDSLLATYDRESPPDSKI--VVNLTLHLRHANIRESESTVRILAD---LQ 274 C+ + +++SLL+ Y + + P + VV++ L A + + + +++ ++ Sbjct: 24 CDEVQAEERLLNSLLSAYSKLTRPVHSVSDVVHVHFGLSIAQLIDVDEKNQMMTTNVWVK 83 Query: 275 MNWIDKRLSWSAGEWG-CSTWLVSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNG 439 W+D RL W+ + G S+ + ++ +W+PD+VL N A GD+ + +A + ++G Sbjct: 84 QEWLDYRLRWTPEDNGNVSSMRIPAQFIWKPDIVLYNNAD---GDFTVTHLTKAHLLHDG 140 Query: 440 SVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFV-----IDKRIYSMFE 604 V+WI + S+ + P D Q CT KFGS ++ ++D + +D+ Y +E Sbjct: 141 RVTWIPPAIYKSSCSIDVTFLPFDQQNCTIKFGSWTYDRSKIDLIRIADSVDQLDY--WE 198 Query: 605 SXAWDVT 625 S W +T Sbjct: 199 SGEWLIT 205 >UniRef50_Q7T2R4 Cluster: Nicotinic acetylcholine receptor alpha 9d subunit; n=7; Clupeocephala|Rep: Nicotinic acetylcholine receptor alpha 9d subunit - Fugu rubripes (Japanese pufferfish) (Takifugu rubripes) Length = 521 Score = 68.5 bits (160), Expect = 2e-10 Identities = 43/152 (28%), Positives = 76/152 (50%), Gaps = 7/152 (4%) Frame = +2 Query: 134 LMIDSLLATYDRESPP--DSKIVVNLTLHLRHANIRESESTVRILAD---LQMNWIDKRL 298 LM D L + Y P D+ ++N+TL + + I + + +IL ++ W+D L Sbjct: 12 LMTD-LFSNYTNALRPVEDTDHIINVTLQITLSQIIDMDERNQILTTYLWVRQVWMDAYL 70 Query: 299 SWSAGEW-GCSTWLVSSERLWRPDVVLLNAAATT-AGDYALRARVSNNGSVSWIKRLDIS 472 +W ++ G T + S +WRPD+VL N+A + + ++G V W + Sbjct: 71 TWKKEDYDGLDTIRIPSSYVWRPDIVLYNSADDEFSSSMETNVVLRHDGQVMWDQPAITK 130 Query: 473 TPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 568 + S+ + ++P D+Q C FGS HN ++MD Sbjct: 131 SSCSVDVAHFPFDLQECHLTFGSWTHNGNQMD 162 >UniRef50_Q17BK7 Cluster: Nicotinic acetylcholine receptor, beta-2 subunit, putative; n=1; Aedes aegypti|Rep: Nicotinic acetylcholine receptor, beta-2 subunit, putative - Aedes aegypti (Yellowfever mosquito) Length = 434 Score = 68.5 bits (160), Expect = 2e-10 Identities = 44/149 (29%), Positives = 72/149 (48%), Gaps = 8/149 (5%) Frame = +2 Query: 149 LLATYDRESPP--DSKIVVNLTLHLRHANIRESESTVRILADL--QMNWIDKRLSWSAGE 316 L +YD P D K VN+++ + EST + A++ M WID+ L W + E Sbjct: 41 LCNSYDANQRPVKDIKFAVNVSVLPVLMSFEYDESTNALNANMLVTMEWIDENLKWDSKE 100 Query: 317 WGCSTWL-VSSERLWRPDVVLLNAAA---TTAGDYALRARVSNNGSVSWIKRLDISTPIS 484 + T + +SS+++W PD L ++ T LR+ V +G+V + D S Sbjct: 101 YNNQTTIAISSDQIWTPDFQLYSSTVKFDTKQSCTNLRSLVKYDGTVIAVPTCDFSARCE 160 Query: 485 MQLDNWPNDMQTCTFKFGSRMHNSDEMDF 571 +WP D Q C FG+ M ++ E+D+ Sbjct: 161 ADYTDWPLDTQRCRMLFGAWMEHAGEVDY 189 >UniRef50_P48182 Cluster: Acetylcholine receptor subunit beta-type acr-2 precursor; n=3; Rhabditida|Rep: Acetylcholine receptor subunit beta-type acr-2 precursor - Caenorhabditis elegans Length = 575 Score = 68.5 bits (160), Expect = 2e-10 Identities = 41/142 (28%), Positives = 70/142 (49%), Gaps = 7/142 (4%) Frame = +2 Query: 227 NIRESESTVRILADLQMNWIDKRLSWSAGEWG-CSTWLVSSERLWRPDVVLLNAA-ATTA 400 N+ E ++ L M W D +L+W+ E+G S V S+R+W PD+VL N A Sbjct: 99 NVDEKNQILQTNVWLTMKWNDFQLAWNPAEYGNISNLHVPSDRVWLPDIVLFNNADGNYE 158 Query: 401 GDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEM----- 565 + V ++G V+W+ + + ++ +P D Q CT FGS +NS+E+ Sbjct: 159 VSFKSNVFVDHHGDVTWVPPAMFKSSCRIDVEWFPFDEQCCTLVFGSWTYNSEEVRLHWY 218 Query: 566 DFVIDKRIYSMFESXAWDVTDL 631 + + +++ S WDV D+ Sbjct: 219 NNIQAVQLHDYSYSGIWDVIDV 240 >UniRef50_P30532 Cluster: Neuronal acetylcholine receptor subunit alpha-5 precursor; n=70; Euteleostomi|Rep: Neuronal acetylcholine receptor subunit alpha-5 precursor - Homo sapiens (Human) Length = 468 Score = 67.7 bits (158), Expect = 3e-10 Identities = 41/173 (23%), Positives = 82/173 (47%), Gaps = 11/173 (6%) Frame = +2 Query: 137 MIDSLLATYDRESPP----DSKIVVNLTLHLRH-ANIRESESTVRILADLQMNWIDKRLS 301 ++ L Y+R P + KI + L + ++ E + L+ WID +L Sbjct: 50 LLKDLFQDYERWVRPVEHLNDKIKIKFGLAISQLVDVDEKNQLMTTNVWLKQEWIDVKLR 109 Query: 302 WSAGEWG-CSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVSWIKRLDISTP 478 W+ ++G V S+ +W PD+VL + A + + + NG+V+W + + Sbjct: 110 WNPDDYGGIKVIRVPSDSVWTPDIVLFDNADGRFEGTSTKTVIRYNGTVTWTPPANYKSS 169 Query: 479 ISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFV-----IDKRIYSMFESXAWDV 622 ++ + +P D+Q C+ KFGS ++ ++D + +DKR F++ W++ Sbjct: 170 CTIDVTFFPFDLQNCSMKFGSWTYDGSQVDIILEDQDVDKR--DFFDNGEWEI 220 >UniRef50_Q4S864 Cluster: Chromosome 5 SCAF14709, whole genome shotgun sequence; n=3; Tetraodontidae|Rep: Chromosome 5 SCAF14709, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 733 Score = 67.3 bits (157), Expect = 4e-10 Identities = 37/121 (30%), Positives = 61/121 (50%), Gaps = 5/121 (4%) Frame = +2 Query: 281 WIDKRLSWSAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGSVSWI 454 W D +L W+ E+G ++ V S R+W+PD+VL N A D +A + NG V+WI Sbjct: 233 WNDYKLRWNPKEYGGVEYIRVPSSRIWKPDIVLYNNAVGDFQVDDKTKALLRYNGDVTWI 292 Query: 455 KRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVI---DKRIYSMFESXAWDVT 625 + + + +P D Q CT KFGS ++ ++D V+ + +E+ W + Sbjct: 293 PPAIFKSSCKIDVTYFPFDYQNCTMKFGSWTYDKAKIDLVLIGSTMNLKDFWETGDWLII 352 Query: 626 D 628 D Sbjct: 353 D 353 Score = 61.7 bits (143), Expect = 2e-08 Identities = 39/120 (32%), Positives = 59/120 (49%), Gaps = 2/120 (1%) Frame = +2 Query: 188 KIVVNLTLHLRHANIRESESTVRILADLQMNWIDKRLSWSAGEW-GCSTWLVSSERLWRP 364 K+ V+L L N RE T + L +W+D RLSW ++ G + + S +W P Sbjct: 37 KLQVSLA-QLISVNEREQIMTTNLW--LMQHWVDYRLSWDPAKYEGINKLRIPSRLIWLP 93 Query: 365 DVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 541 D+VL N A T A V NGS++W+ + +++ ++P D Q CT KF S Sbjct: 94 DIVLYNNADGTYEVTVYTNAIVLFNGSINWLPPAIYKSACKIEVKHFPFDQQNCTLKFRS 153 >UniRef50_Q27218 Cluster: Acetylcholine receptor subunit beta-type lev-1 precursor; n=6; Caenorhabditis|Rep: Acetylcholine receptor subunit beta-type lev-1 precursor - Caenorhabditis elegans Length = 507 Score = 67.3 bits (157), Expect = 4e-10 Identities = 46/159 (28%), Positives = 76/159 (47%), Gaps = 6/159 (3%) Frame = +2 Query: 170 ESPPDSKIVVNLTLHLRHANIRESESTVRILADLQMNWIDKRLSWSAGEWGCSTWL-VSS 346 E P KI + L L + N+ E E + L M W D +L W ++ T + V+ Sbjct: 61 ELPMIVKIGMQLVLLI---NVDEKEQVMHTNVWLTMKWDDFQLKWDPRDYANITQIRVAP 117 Query: 347 ERLWRPDVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTC 523 E++W PD+VL N A + + + G+V W+ + + ++ +P D Q C Sbjct: 118 EKVWLPDIVLFNNADGNYEVSFMCNVLILSTGTVLWVPPAIYKSSCIIDVEFFPFDDQLC 177 Query: 524 TFKFGSRMHNSDE--MDFVIDKRI-YSMFE-SXAWDVTD 628 + FGS +N DE +DF+ R+ +S + S WD+ D Sbjct: 178 SLTFGSWTYNRDEIKLDFLTSDRVDFSEYSTSSIWDMMD 216 >UniRef50_P91766 Cluster: Acetylcholine receptor subunit alpha-like precursor; n=31; Coelomata|Rep: Acetylcholine receptor subunit alpha-like precursor - Manduca sexta (Tobacco hawkmoth) (Tobacco hornworm) Length = 516 Score = 67.3 bits (157), Expect = 4e-10 Identities = 44/165 (26%), Positives = 75/165 (45%), Gaps = 9/165 (5%) Frame = +2 Query: 101 AAECENATSLSLMIDSLLATYDRESPPDSKIVVNLTLHLR-------HANIRESESTVRI 259 A C + D LL+ Y++ P + LT+ ++ N++ T + Sbjct: 16 ATGCAGNPDAKRLYDDLLSNYNKLVRPVLNVSDALTVRIKLKLSQLIDVNLKNQIMTTNL 75 Query: 260 LADLQMNWIDKRLSWSAGEWGCSTWL-VSSERLWRPDVVLLNAA-ATTAGDYALRARVSN 433 ++ +W D +LSW E+G L V S+ +WRPD+VL N A A +A ++ Sbjct: 76 W--VEQSWYDYKLSWEPREYGGVEMLHVPSDHIWRPDIVLYNNADGNFEVTLATKATLNY 133 Query: 434 NGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 568 G V W + + ++ +P D QTC KFGS ++ ++D Sbjct: 134 TGRVEWRPPAIYKSSCEIDVEYFPFDQQTCVMKFGSWTYDGFQVD 178 >UniRef50_Q60KR8 Cluster: Putative uncharacterized protein CBG23934; n=1; Caenorhabditis briggsae|Rep: Putative uncharacterized protein CBG23934 - Caenorhabditis briggsae Length = 551 Score = 66.9 bits (156), Expect = 6e-10 Identities = 42/167 (25%), Positives = 80/167 (47%), Gaps = 8/167 (4%) Frame = +2 Query: 98 SAAECENATSLSLMIDSLLATYDRES-PPDSK----IVVNLTLHLRH-ANIRESESTVRI 259 S + + T+ + ++LL+ Y+R + PP K + + L L ++ E + + + Sbjct: 10 SLFKLNDCTAYKNLFETLLSRYNRIAFPPGEKHNNSLKIEFKLRLDQIVDVHEKDQVITL 69 Query: 260 LADLQMNWIDKRLSWSAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAG-DYALRARVSN 433 L W D RLSW+ E+G T + E +W PD++L N A + + VS+ Sbjct: 70 KGILVHRWHDIRLSWNPQEFGDITLMHFPGEMIWLPDIILYNNAHGSPWVSETTQVHVSH 129 Query: 434 NGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFV 574 G V+W + ++ ++ +P D+Q C KFGS + +++ + Sbjct: 130 EGRVTWHPPVAYDAFCNIDIEWYPYDLQICELKFGSWTYGGSQLNLI 176 >UniRef50_Q5BW84 Cluster: SJCHGC08361 protein; n=1; Schistosoma japonicum|Rep: SJCHGC08361 protein - Schistosoma japonicum (Blood fluke) Length = 213 Score = 66.9 bits (156), Expect = 6e-10 Identities = 38/152 (25%), Positives = 73/152 (48%), Gaps = 8/152 (5%) Frame = +2 Query: 140 IDSLLATYDRESPP----DSKIVVNLTLHLRH-ANIRESESTVRILADLQMNWIDKRLSW 304 ID+L+ Y+ P K+ V +++ L+ + E + + L+ W D L W Sbjct: 16 IDTLMKNYESSVRPLKNISEKLTVKISIRLQQIGGLNERNQVLTTILFLEQIWEDDYLKW 75 Query: 305 SAGEWG-CSTWLVSSERLWRPDVVLLNAAATTAGDY--ALRARVSNNGSVSWIKRLDIST 475 + E+G T + ++++W PD + N A T + + + ++G VSW + + T Sbjct: 76 NESEFGNVRTLRIPAKQVWTPDTYVFNNADHTNSGFLEGIYVIIHSSGKVSWPIPVQLKT 135 Query: 476 PISMQLDNWPNDMQTCTFKFGSRMHNSDEMDF 571 + + +P D Q C +FGS M+ SD +++ Sbjct: 136 SCKVDITLFPFDHQNCEIQFGSWMYKSDWIEY 167 >UniRef50_UPI0000EBE733 Cluster: PREDICTED: similar to nicotinic acetylcholine receptor alpha6 subunit; n=2; Bos taurus|Rep: PREDICTED: similar to nicotinic acetylcholine receptor alpha6 subunit - Bos taurus Length = 630 Score = 66.5 bits (155), Expect = 8e-10 Identities = 46/188 (24%), Positives = 86/188 (45%), Gaps = 13/188 (6%) Frame = +2 Query: 110 CENATSLSLMIDSLLATYDRESPPDSKIVVNLTLHL-----RHANIRESESTVRILADLQ 274 C S + L A Y++ P + +T++ + A++ E + L+ Sbjct: 33 CAGCASEERLFHKLFAHYNQFIRPVENVSDPITVYFEVAITQLADVDEVNQIMETNLWLR 92 Query: 275 MNWIDKRLSWSAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRAR----VSNNG 439 W D +L W E+ G T V +E +W+PD+VL N A GD+ ++ + + +G Sbjct: 93 HIWNDYKLRWDPTEYDGIETLRVPAEMIWKPDIVLYNNAV---GDFQVKGKTKALLKYDG 149 Query: 440 SVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD-FVIDKRI--YSMFESX 610 ++W + M + +P D Q C+ KFGS ++ E+D +I ++ +E+ Sbjct: 150 MITWTPPAIFKSSCPMDITFFPFDHQNCSLKFGSWTYDKAEIDLLIIGSKVDMNEFWENS 209 Query: 611 AWDVTDLS 634 W++ D S Sbjct: 210 EWEIVDAS 217 >UniRef50_UPI0000E49401 Cluster: PREDICTED: similar to alpha 10 subunit of nicotinic acetylcholine receptor; n=1; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to alpha 10 subunit of nicotinic acetylcholine receptor - Strongylocentrotus purpuratus Length = 347 Score = 66.5 bits (155), Expect = 8e-10 Identities = 31/105 (29%), Positives = 57/105 (54%), Gaps = 2/105 (1%) Frame = +2 Query: 266 DLQMNWIDKRLSWSAGEWGCSTWL-VSSERLWRPDVVLLNAAATT-AGDYALRARVSNNG 439 +LQ W D L W+ ++G T + + S +W+PD++L N A ++ G A VSN+G Sbjct: 87 NLQFEWSDPNLKWNPDDYGGITKITIPSSNIWKPDILLYNNADSSFKGAMKTNAAVSNDG 146 Query: 440 SVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFV 574 V+W + + ++ +P D Q CT +FGS + ++ ++ + Sbjct: 147 IVTWFAPAIFRSSCKININYFPFDKQECTLQFGSWAYTTEHLNLL 191 >UniRef50_Q2XWL1 Cluster: Nicotinic acetylcholine receptor subunit type B; n=1; Lymnaea stagnalis|Rep: Nicotinic acetylcholine receptor subunit type B - Lymnaea stagnalis (Great pond snail) Length = 527 Score = 66.5 bits (155), Expect = 8e-10 Identities = 38/125 (30%), Positives = 67/125 (53%), Gaps = 8/125 (6%) Frame = +2 Query: 278 NWIDKRLSWSAGEWG-CSTWLVSSERLWRPDVVLLNAAATTAGDYALRARV-SNNGSVSW 451 +WID L+W+ E+G +T V+++ +W+PD+ L N A T + V S+NG V W Sbjct: 88 SWIDMYLAWNESEYGNITTVRVNNDDIWKPDIKLYNYADTRLEEKREALCVLSSNGEVVW 147 Query: 452 IKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVI---DKRIYSMFE---SXA 613 I + + S+ + ++P D+Q C KFGS ++ ++D D + + M + S Sbjct: 148 IPQAVFKSSCSIDIRHFPFDVQRCDMKFGSWTYDGSKLDIQFRYPDVKGFEMDDYIVSNE 207 Query: 614 WDVTD 628 WD+ + Sbjct: 208 WDIVE 212 >UniRef50_A7S3F7 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 334 Score = 66.5 bits (155), Expect = 8e-10 Identities = 41/143 (28%), Positives = 73/143 (51%), Gaps = 8/143 (5%) Frame = +2 Query: 137 MIDSLLATYDRESPP---DSKIV-VNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLS 301 +I LL TY+ + P D+ V + LT+ L+ ++ E ++ L+ W D RL+ Sbjct: 7 LIHDLLDTYNPRARPVTNDNHTVGLKLTIRLQQIMDVDEKNEVIQTFLILEQMWNDTRLA 66 Query: 302 WSAGEWG-CSTWLVSSERLWRPDVVLLNAAATTAG--DYALRARVSNNGSVSWIKRLDIS 472 W+ E+G + S+ +W PD+ +LN+A + +R +++ G V W+ L + Sbjct: 67 WNETEYGGIKQMTLRSKLIWTPDISVLNSANKDMDLREKNIRLFINSAGEVLWMNPLILH 126 Query: 473 TPISMQLDNWPNDMQTCTFKFGS 541 T M + ++P D Q C +FGS Sbjct: 127 TSCGMDIAHFPFDNQACELRFGS 149 >UniRef50_Q4RRI3 Cluster: Chromosome 16 SCAF15002, whole genome shotgun sequence; n=3; Euteleostomi|Rep: Chromosome 16 SCAF15002, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 636 Score = 66.1 bits (154), Expect = 1e-09 Identities = 41/172 (23%), Positives = 82/172 (47%), Gaps = 10/172 (5%) Frame = +2 Query: 137 MIDSLLATYDRESPP--DSKIVVNLTLHLRHANIRESESTVRILAD---LQMNWIDKRLS 301 ++ L + Y P D+ ++N+TL + + I + + +IL ++ W+D L Sbjct: 13 LLTDLFSNYTSALRPVEDTHNILNVTLQVTLSQIIDMDERNQILTAYLWIRRVWVDAHLK 72 Query: 302 WSAGEW-GCSTWLVSSERLWRPDVVLLNAAATT-AGDYALRARVSNNGSVSWIKRLDIST 475 W+ E+ G T + S +WRPD+VL N A G + ++G ++W + Sbjct: 73 WNKDEYDGLDTIRIPSSYVWRPDIVLYNNADDHFTGPMDTNVVIRHDGQITWDSPAITKS 132 Query: 476 PISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFV--IDKR-IYSMFESXAWDV 622 + + +P D Q C F +GS +N +++D + +D + + E+ W++ Sbjct: 133 SCRVDVSFFPFDAQQCRFTYGSWTYNGNQLDILNALDSADLADLVENVEWEI 184 >UniRef50_O44497 Cluster: Putative uncharacterized protein; n=2; Caenorhabditis|Rep: Putative uncharacterized protein - Caenorhabditis elegans Length = 445 Score = 66.1 bits (154), Expect = 1e-09 Identities = 34/151 (22%), Positives = 66/151 (43%), Gaps = 2/151 (1%) Frame = +2 Query: 98 SAAECENATSLSLMIDSLLATYDRESPPDSKIVVNLTLHLRHANIRESESTVRILADLQM 277 S C+ + + TY + +K+V ++ + + I E V++ + Sbjct: 54 SCHSCQGGDRAWKLRTHIQTTYQNATDNKTKVVRVESVRINNVEIDERRQNVKVFGRFVL 113 Query: 278 NWIDKRLSWSAGEWGCSTWLVSSERLWRPDVVLLNAAATT-AGDYALRARVSN-NGSVSW 451 +W D +SW +WG S ++W P++V +N +T+ G + +N G + Sbjct: 114 SWNDTMVSWDKEQWGLSWLNFYWIQIWTPNIVQINGGSTSNPGQVTSKVLAANYTGQIYL 173 Query: 452 IKRLDISTPISMQLDNWPNDMQTCTFKFGSR 544 +TP Q +++PNDMQ +KF + Sbjct: 174 WSDFSFTTPFRFQYEDYPNDMQRVCYKFDDK 204 >UniRef50_P17787 Cluster: Neuronal acetylcholine receptor subunit beta-2 precursor; n=69; Euteleostomi|Rep: Neuronal acetylcholine receptor subunit beta-2 precursor - Homo sapiens (Human) Length = 502 Score = 66.1 bits (154), Expect = 1e-09 Identities = 43/153 (28%), Positives = 71/153 (46%), Gaps = 6/153 (3%) Frame = +2 Query: 191 IVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWSAGEW-GCSTWLVSSERLWRP 364 + V L + L ++ E E + L W D RL+W E+ + S+ +W P Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115 Query: 365 DVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 541 DVVL N A + A VS +GS+ W+ + +++ ++P D Q CT KF S Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRS 175 Query: 542 RMHNSDEMDFVIDKRIYSMFE---SXAWDVTDL 631 ++ E+D V+ + S+ + S WD+ L Sbjct: 176 WTYDRTEIDLVLKSEVASLDDFTPSGEWDIVAL 208 >UniRef50_P17644 Cluster: Acetylcholine receptor subunit alpha-like 2 precursor; n=38; Neoptera|Rep: Acetylcholine receptor subunit alpha-like 2 precursor - Drosophila melanogaster (Fruit fly) Length = 576 Score = 66.1 bits (154), Expect = 1e-09 Identities = 48/156 (30%), Positives = 74/156 (47%), Gaps = 12/156 (7%) Frame = +2 Query: 137 MIDSLLATYDRESPPDSK----IVVNLTLHLRHA---NIRESESTVRILADLQMNWIDKR 295 + D LL+ Y+R P S ++V L L L N+++ T + L+ W D + Sbjct: 48 LYDDLLSNYNRLIRPVSNNTDTVLVKLGLRLSQLIDLNLKDQILTTNVW--LEHEWQDHK 105 Query: 296 LSWSAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNGSVSWIKR 460 W E+G T L V SE +W PD+VL N A G+Y + +A + G V W Sbjct: 106 FKWDPSEYGGVTELYVPSEHIWLPDIVLYNNAD---GEYVVTTMTKAILHYTGKVVWTPP 162 Query: 461 LDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 568 + + + +P D QTC KFGS ++ D++D Sbjct: 163 AIFKSSCEIDVRYFPFDQQTCFMKFGSWTYDGDQID 198 >UniRef50_Q4RIA9 Cluster: Chromosome 8 SCAF15044, whole genome shotgun sequence; n=3; Clupeocephala|Rep: Chromosome 8 SCAF15044, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 549 Score = 65.7 bits (153), Expect = 1e-09 Identities = 44/153 (28%), Positives = 72/153 (47%), Gaps = 6/153 (3%) Frame = +2 Query: 191 IVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWSAGEW-GCSTWLVSSERLWRP 364 + V L + L ++ E E + L W D RL+W E+ G + S+ +W P Sbjct: 30 VTVQLMVSLAQLISVHEREQVMTTNVWLTQEWQDYRLTWIPEEFDGMLKVRLPSKHIWLP 89 Query: 365 DVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 541 DVVL N A + A VS +GS+ W+ + +++ ++P D Q CT +F S Sbjct: 90 DVVLYNNADGVYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTLRFRS 149 Query: 542 RMHNSDEMDFVIDKRIYSMFE---SXAWDVTDL 631 ++ E+D V+ + SM + S WD+ L Sbjct: 150 WTYDRTEIDLVLRADVASMDDFTPSGEWDIIAL 182 >UniRef50_P43681 Cluster: Neuronal acetylcholine receptor subunit alpha-4 precursor; n=35; Euteleostomi|Rep: Neuronal acetylcholine receptor subunit alpha-4 precursor - Homo sapiens (Human) Length = 627 Score = 65.7 bits (153), Expect = 1e-09 Identities = 48/177 (27%), Positives = 88/177 (49%), Gaps = 13/177 (7%) Frame = +2 Query: 137 MIDSLLATYDRESPPDSKI--VVNLTLHLRHANIRESESTVRILAD---LQMNWIDKRLS 301 ++ L + Y++ S P + I VV + L A + + + +++ ++ W D +L Sbjct: 40 LLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLR 99 Query: 302 WSAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNGSVSWIKRLD 466 W ++ T + + SE +WRPD+VL N A GD+A+ +A + ++G V W Sbjct: 100 WDPADYENVTSIRIPSELIWRPDIVLYNNAD---GDFAVTHLTKAHLFHDGRVQWTPPAI 156 Query: 467 ISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFV-IDKRI--YSMFESXAWDVTD 628 + S+ + +P D Q CT KFGS ++ ++D V + R+ +ES W + D Sbjct: 157 YKSSCSIDVTFFPFDQQNCTMKFGSWTYDKAKIDLVNMHSRVDQLDFWESGEWVIVD 213 >UniRef50_UPI00015B4A35 Cluster: PREDICTED: similar to nicotinic acetylcholine receptor alpha9 subunit; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to nicotinic acetylcholine receptor alpha9 subunit - Nasonia vitripennis Length = 431 Score = 64.9 bits (151), Expect = 2e-09 Identities = 41/149 (27%), Positives = 65/149 (43%), Gaps = 8/149 (5%) Frame = +2 Query: 149 LLATYDRESPP--DSKIVVNLTLHLRHA--NIRESESTVRILADLQMNWIDKRLSWSAGE 316 L YD P VN+++ +R N + +ST + A + W D+ L+W + Sbjct: 39 LFCEYDTSIRPVLSKNTAVNVSVVIRPMLMNFIDDKSTFILHAWISFEWTDQHLTWKPED 98 Query: 317 W-GCSTWLVSSERLWRPDVVLLNAA---ATTAGDYALRARVSNNGSVSWIKRLDISTPIS 484 + G V S+ +W PD L N+ + G ++S+ GSV + + T Sbjct: 99 FDGVQETRVKSDEIWVPDFALYNSGDMETSQTGIPETLCQLSHTGSVICLPSIKYKTLCE 158 Query: 485 MQLDNWPNDMQTCTFKFGSRMHNSDEMDF 571 WP D QTCT + GS H +E+ F Sbjct: 159 SDFTYWPYDKQTCTLRMGSWTHTGEEISF 187 >UniRef50_Q66T35 Cluster: Nicotinic acetylcholine receptor subunit alpha 3; n=7; Coelomata|Rep: Nicotinic acetylcholine receptor subunit alpha 3 - Anopheles gambiae (African malaria mosquito) Length = 710 Score = 64.5 bits (150), Expect = 3e-09 Identities = 50/190 (26%), Positives = 84/190 (44%), Gaps = 10/190 (5%) Frame = +2 Query: 95 ASAAECENATSLSLMIDSLLATYDRESPPDSKIVVNLTLHLR-------HANIRESESTV 253 A + C + D LL+ Y++ P + LT+ ++ N++ T Sbjct: 13 AVVSVCGGNPDAKRLYDDLLSNYNKLVRPVVNVTDALTVKIKLKLSQLIDVNLKNQIMTT 72 Query: 254 RILADLQMNWIDKRLSWSAGEWGCSTWL-VSSERLWRPDVVLLNAA-ATTAGDYALRARV 427 + ++ W D +L W E+G L V S+ +WRPD+VL N A A +A + Sbjct: 73 NLW--VEQTWYDYKLKWEPKEYGGVEMLHVPSDHIWRPDIVLYNNADGNFEVTLATKATL 130 Query: 428 SNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDKRIYSMFES 607 + G V W + + ++ +P D QTC KFGS ++ ++D + I M E+ Sbjct: 131 NYTGRVEWRPPAIYKSSCEIDVEYFPFDEQTCVMKFGSWTYDGFQVDL---RHIDEMNET 187 Query: 608 XAWDV-TDLS 634 +V DLS Sbjct: 188 NVVEVGVDLS 197 >UniRef50_A7RHV9 Cluster: Predicted protein; n=3; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 336 Score = 64.5 bits (150), Expect = 3e-09 Identities = 39/138 (28%), Positives = 71/138 (51%), Gaps = 8/138 (5%) Frame = +2 Query: 200 NLTLHLRHANIRESESTVRILAD---LQMNWIDKRLSWSAGEWG-CSTWLVSSERLWRPD 367 N+TL + +I + + +IL+ ++ +WI + LSW E+G + +VSS+ LW+PD Sbjct: 38 NVTLDITFNSIIDVDEKHQILSSSVWIRQSWIAETLSWDPAEYGGVNQIVVSSQLLWQPD 97 Query: 368 VVLLNAAA----TTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKF 535 VL N + R RV ++G V W T + + ++P D Q C F Sbjct: 98 TVLYNNIFEEFDSRLDTTVTRVRVYSSGFVYWAMPYVFKTMCKIDVTDFPFDSQRCPITF 157 Query: 536 GSRMHNSDEMDFVIDKRI 589 G+ ++ +E++ + +KR+ Sbjct: 158 GAWQYDQNEVNLINNKRL 175 >UniRef50_A0EIZ7 Cluster: Nicotinic acetylcholine receptor alpha9 subunit; n=1; Apis mellifera|Rep: Nicotinic acetylcholine receptor alpha9 subunit - Apis mellifera (Honeybee) Length = 431 Score = 64.5 bits (150), Expect = 3e-09 Identities = 43/170 (25%), Positives = 79/170 (46%), Gaps = 8/170 (4%) Frame = +2 Query: 113 ENATSLSLMIDSLLATYDRESPPDS--KIVVNLTLHL--RHANIRESESTVRILADLQMN 280 ++ T+L + L YD P S +I N+T+ L + + S + + + + + Sbjct: 39 DHPTTLLKLKRYLFCEYDPNVRPISSHQIANNVTMQLLPKLMEFDDWTSVMELHSWMTLM 98 Query: 281 WIDKRLSWSAGEW-GCSTWLVSSERLWRPDVVLLNAAATT---AGDYALRARVSNNGSVS 448 W D LSW ++ G + V S+ +W PD+ + N+ T G V ++GSVS Sbjct: 99 WTDSHLSWKPSDFDGINYIYVKSDDIWVPDISVYNSGDMTFDQTGIPPTTCLVFSSGSVS 158 Query: 449 WIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDKRIYSM 598 + + + +WP D C FGS +H+ +E++ +DK+ + M Sbjct: 159 CVPSVKHVAKCATDFSSWPYDTHRCRINFGSWVHSGEEVNIFLDKKGFHM 208 >UniRef50_Q04844 Cluster: Acetylcholine receptor subunit epsilon precursor; n=35; Euteleostomi|Rep: Acetylcholine receptor subunit epsilon precursor - Homo sapiens (Human) Length = 493 Score = 64.5 bits (150), Expect = 3e-09 Identities = 37/134 (27%), Positives = 71/134 (52%), Gaps = 3/134 (2%) Frame = +2 Query: 179 PDSKIVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWSAGEWG-CSTWLVSSER 352 P+ + ++L + L + ++ E E T+ + ++W D RL++S ++G T V SE Sbjct: 45 PEDTVTISLKVTLTNLISLNEKEETLTTSVWIGIDWQDYRLNYSKDDFGGIETLRVPSEL 104 Query: 353 LWRPDVVLLNAAATTAG-DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTF 529 +W P++VL N G Y V GSV+W+ + ++++ +P D Q C+ Sbjct: 105 VWLPEIVLENNIDGQFGVAYDANVLVYEGGSVTWLPPAIYRSVCAVEVTYFPFDWQNCSL 164 Query: 530 KFGSRMHNSDEMDF 571 F S+ +N++E++F Sbjct: 165 IFRSQTYNAEEVEF 178 >UniRef50_P11230 Cluster: Acetylcholine receptor subunit beta precursor; n=30; Gnathostomata|Rep: Acetylcholine receptor subunit beta precursor - Homo sapiens (Human) Length = 501 Score = 64.5 bits (150), Expect = 3e-09 Identities = 47/137 (34%), Positives = 69/137 (50%), Gaps = 4/137 (2%) Frame = +2 Query: 167 RESPPDSKIVVNLTL-HLRHANIRESESTVRILADLQMNWIDKRLSWSAGEW-GCSTWLV 340 RE ++ V L L L N ++ E + ++ DL+ W D RLSW E G + + Sbjct: 46 REVGDRVRVSVGLILAQLISLNEKDEEMSTKVYLDLE--WTDYRLSWDPAEHDGIDSLRI 103 Query: 341 SSERLWRPDVVLLNAAATTAGDYAL--RARVSNNGSVSWIKRLDISTPISMQLDNWPNDM 514 ++E +W PDVVLLN D AL VS++GSV W + S+Q+ +P D Sbjct: 104 TAESVWLPDVVLLNNNDGNF-DVALDISVVVSSDGSVRWQPPGIYRSSCSIQVTYFPFDW 162 Query: 515 QTCTFKFGSRMHNSDEM 565 Q CT F S ++S E+ Sbjct: 163 QNCTMVFSSYSYDSSEV 179 >UniRef50_UPI0001560C7D Cluster: PREDICTED: similar to cholinergic receptor, nicotinic, alpha 2 (neuronal); n=2; Laurasiatheria|Rep: PREDICTED: similar to cholinergic receptor, nicotinic, alpha 2 (neuronal) - Equus caballus Length = 630 Score = 64.1 bits (149), Expect = 4e-09 Identities = 46/163 (28%), Positives = 77/163 (47%), Gaps = 9/163 (5%) Frame = +2 Query: 161 YDRESPPDSKIV-VNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWSAGEWGCSTW 334 Y R P S +V V L + ++ E + L+ W D +L W+ ++G T Sbjct: 71 YARPVPNTSDVVIVRFGLSIAQLIDVDEKNQMMTTNVWLKQEWSDYKLRWNPADFGNITS 130 Query: 335 L-VSSERLWRPDVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPN 508 L V SE +W PD+VL N A A + +A + + G+V W+ + S+ + +P Sbjct: 131 LRVPSEMIWIPDIVLYNNADGEFAVTHMTKAHLFSTGTVHWVPPAIYKSSCSIDVTFFPF 190 Query: 509 DMQTCTFKFGSRMHNS-----DEMDFVIDKRIYSMFESXAWDV 622 D Q C KFGS ++ ++M+ +D + Y +ES W + Sbjct: 191 DQQNCKMKFGSWTYDKAKIDLEQMEQTVDLKDY--WESGEWAI 231 >UniRef50_Q4SXG5 Cluster: Chromosome undetermined SCAF12416, whole genome shotgun sequence; n=3; Tetraodontidae|Rep: Chromosome undetermined SCAF12416, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 643 Score = 64.1 bits (149), Expect = 4e-09 Identities = 45/166 (27%), Positives = 84/166 (50%), Gaps = 6/166 (3%) Frame = +2 Query: 89 AIASAAECENATSLSLMIDSLLATYDRESPPDSKIVVNLTLHLRH---ANIRESESTVRI 259 ++ A E E+A +L + L SP + ++VV + + L N++ E + + Sbjct: 16 SLGGAFEVESALLKNLFSNYTLKVRPAVSP-EQRVVVRVGMILSSFVGLNMKNEEMSTIV 74 Query: 260 LADLQMNWIDKRLSWSAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVS-- 430 + +L+ W D RLSWS ++ G + S ++W PD+VL+N + AL+ V Sbjct: 75 VMNLE--WTDYRLSWSPKDYDGIEVLRIPSGKIWLPDIVLINNNDGVF-EVALQVHVQVY 131 Query: 431 NNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 568 +NG V+W + ++++ +P D Q C+ +F S ++S E+D Sbjct: 132 SNGRVTWTPPALYCSSCGVKVEYFPFDWQNCSMQFRSYTYDSTEID 177 >UniRef50_A7T134 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 301 Score = 64.1 bits (149), Expect = 4e-09 Identities = 50/184 (27%), Positives = 81/184 (44%), Gaps = 18/184 (9%) Frame = +2 Query: 137 MIDSLLATYDRESPP--DSKIVVNLTLHLRHANI-----RESESTVRILADLQMNWIDKR 295 ++D L YD+ P D VV L L L+ I +E E R+ + W D + Sbjct: 4 LLDQLFQGYDKRVRPVTDPSDVVELKLGLKIQKIVKIDSKEQEMITRVW--VTQVWRDPK 61 Query: 296 LSWSAGEWG-CSTWLVSSERLWRPDVVLLNAA---ATTAGD---YALRARVSNNGSVSWI 454 L W + G T V +W PD+ L N A + AG + + V+N G V W Sbjct: 62 LRWDVEKGGGIETIFVDPSEIWTPDISLYNNADDSVSVAGSEKKFQTKIVVANTGKVVWQ 121 Query: 455 KRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDF--VIDKRIYS--MFESXAWDV 622 + S+++ WP D+Q C+ FGS + + ++ + D Y+ +S WD+ Sbjct: 122 SPATFRSECSIKIRYWPFDVQKCSMTFGSFIFPASALNVTSLYDSSFYTDRFMQSGDWDI 181 Query: 623 TDLS 634 ++S Sbjct: 182 KEVS 185 >UniRef50_P04755 Cluster: Acetylcholine receptor subunit beta-like 1 precursor; n=20; Protostomia|Rep: Acetylcholine receptor subunit beta-like 1 precursor - Drosophila melanogaster (Fruit fly) Length = 521 Score = 64.1 bits (149), Expect = 4e-09 Identities = 36/145 (24%), Positives = 70/145 (48%), Gaps = 10/145 (6%) Frame = +2 Query: 227 NIRESESTVRILADLQMNWIDKRLSWSAGEWG-CSTWLVSSERLWRPDVVLLNAAATTAG 403 N+ E ++ L++ W D +L W ++G + +++W+PD+VL N A G Sbjct: 66 NVNEKNQVMKSNVWLRLVWYDYQLQWDEADYGGIGVLRLPPDKVWKPDIVLFNNAD---G 122 Query: 404 DYALRAR----VSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDF 571 +Y +R + + G V W+ + ++ + +P D QTC KFGS N D++ Sbjct: 123 NYEVRYKSNVLIYPTGEVLWVPPAIYQSSCTIDVTYFPFDQQTCIMKFGSWTFNGDQVSL 182 Query: 572 VI--DKRIYSM---FESXAWDVTDL 631 + +K + ++S WD+ ++ Sbjct: 183 ALYNNKNFVDLSDYWKSGTWDIIEV 207 >UniRef50_Q93329 Cluster: Putative uncharacterized protein lev-8; n=2; Caenorhabditis|Rep: Putative uncharacterized protein lev-8 - Caenorhabditis elegans Length = 531 Score = 63.7 bits (148), Expect = 5e-09 Identities = 39/154 (25%), Positives = 75/154 (48%), Gaps = 7/154 (4%) Frame = +2 Query: 128 LSLMIDSLLATYDRESPP----DSKIVVNLTLHL-RHANIRESESTVRILADLQMNWIDK 292 +S ++++LL Y++ P + V +L R ++ E + L+M W DK Sbjct: 29 VSQLLENLLTDYNKAVRPVHNASDALKVKFGANLCRLIDVDEVNQVLTTSLWLEMQWYDK 88 Query: 293 RLSWSAGEWGCSTWL-VSSERLWRPDVVLL-NAAATTAGDYALRARVSNNGSVSWIKRLD 466 +L+W+ +WG ++ + S+++W PD+VL NA A++ ++G V W Sbjct: 89 KLTWNPTDWGGVEYIHIPSDQIWIPDIVLYNNADGEPHITITSLAKIDHHGRVVWQPPSI 148 Query: 467 ISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 568 + + + +P D QTC KFG ++ + +D Sbjct: 149 YKSFCPINIKYFPYDWQTCEMKFGGWSNDGETLD 182 >UniRef50_Q0GQR6 Cluster: GABA-gated ion channel; n=2; Apis mellifera|Rep: GABA-gated ion channel - Apis mellifera (Honeybee) Length = 463 Score = 63.7 bits (148), Expect = 5e-09 Identities = 41/149 (27%), Positives = 70/149 (46%), Gaps = 7/149 (4%) Frame = +2 Query: 116 NATSLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESESTVRILADLQMNW 283 N +++S ++D+LL YD PD V + + +R I E + T + + +W Sbjct: 2 NHSNISELLDNLLRGYDNSVRPDFGGPPATVEVDIMVRSMGPISEVDMTYSMDCYFRQSW 61 Query: 284 IDKRLSWSAGEWGCSTWLVSSERLWRPDVVLLNAAAT---TAGDYALRARVSNNGSVSWI 454 +D+RL++ G+ + + R+W+PD N + T R+ +G V + Sbjct: 62 VDRRLAFQGGKETLALSISMLARIWKPDTYFYNGKHSYLHTITSPNKFVRLYQDGRVLYS 121 Query: 455 KRLDISTPISMQLDNWPNDMQTCTFKFGS 541 RL I M L+N+P D Q C +FGS Sbjct: 122 SRLTIKAGCPMNLENFPMDTQRCPLQFGS 150 >UniRef50_Q15822 Cluster: Neuronal acetylcholine receptor subunit alpha-2 precursor; n=98; Euteleostomi|Rep: Neuronal acetylcholine receptor subunit alpha-2 precursor - Homo sapiens (Human) Length = 529 Score = 63.7 bits (148), Expect = 5e-09 Identities = 38/127 (29%), Positives = 65/127 (51%), Gaps = 7/127 (5%) Frame = +2 Query: 269 LQMNWIDKRLSWSAGEWGCSTWL-VSSERLWRPDVVLLNAA-ATTAGDYALRARVSNNGS 442 L+ W D +L W+ ++G T L V SE +W PD+VL N A A + +A + + G+ Sbjct: 111 LKQEWSDYKLRWNPADFGNITSLRVPSEMIWIPDIVLYNNADGEFAVTHMTKAHLFSTGT 170 Query: 443 VSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNS-----DEMDFVIDKRIYSMFES 607 V W+ + S+ + +P D Q C KFGS ++ ++M+ +D + Y +ES Sbjct: 171 VHWVPPAIYKSSCSIDVTFFPFDQQNCKMKFGSWTYDKAKIDLEQMEQTVDLKDY--WES 228 Query: 608 XAWDVTD 628 W + + Sbjct: 229 GEWAIVN 235 >UniRef50_Q8JFN7 Cluster: Neuronal acetylcholine receptor subunit alpha-9-I precursor; n=8; Clupeocephala|Rep: Neuronal acetylcholine receptor subunit alpha-9-I precursor - Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri) Length = 572 Score = 63.7 bits (148), Expect = 5e-09 Identities = 38/154 (24%), Positives = 70/154 (45%), Gaps = 7/154 (4%) Frame = +2 Query: 137 MIDSLLATYDRESPP--DSKIVVNLTLHLRHANIRESESTVRILAD---LQMNWIDKRLS 301 +++ L+ Y P D+ +N+TL + + I++ + ++L ++ W D L Sbjct: 28 LLNDLMENYSSALRPVEDTDKTLNVTLQITLSQIKDMDERNQVLTTYLWIRQTWFDAYLK 87 Query: 302 WSAGEW-GCSTWLVSSERLWRPDVVLLNAAATTA-GDYALRARVSNNGSVSWIKRLDIST 475 W E+ G + S +WRPD+VL N A A G + NG ++W + Sbjct: 88 WDKEEYDGLEVIRIPSNLVWRPDIVLYNKADEEASGPADTNVVLRYNGEITWDMPAITKS 147 Query: 476 PISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVI 577 + + +P D Q C FGS +N +++D + Sbjct: 148 SCVVDVSYFPFDWQWCNLTFGSWTYNGNQVDIAM 181 >UniRef50_UPI00015B5C4C Cluster: PREDICTED: similar to GABA-gated ion channel; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to GABA-gated ion channel - Nasonia vitripennis Length = 442 Score = 63.3 bits (147), Expect = 7e-09 Identities = 41/152 (26%), Positives = 72/152 (47%), Gaps = 7/152 (4%) Frame = +2 Query: 107 ECENATSLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESESTVRILADLQ 274 + N ++S ++D+LL YD P+ VV + + +R I E + T + + Sbjct: 43 QSNNHGNISELLDNLLRGYDNSVRPNFGGPPAVVEVDIMVRSMGPISEVDMTYSMDCYFR 102 Query: 275 MNWIDKRLSWSAGEWGCSTWLVSSERLWRPDVVLLNAAAT---TAGDYALRARVSNNGSV 445 +W+D+RL++ +G+ + + R+W+PD N + T R+ +G V Sbjct: 103 QSWVDRRLAFQSGKETLALSISMLARIWKPDTYFYNGKQSYLHTITSPNKFVRLYQDGRV 162 Query: 446 SWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 541 + RL I M L+++P D Q C KFGS Sbjct: 163 LYSSRLTIKAACPMNLEDFPMDTQRCPLKFGS 194 >UniRef50_UPI0000E47D8F Cluster: PREDICTED: similar to nicotinic acetylcholine receptor alpha 7c subunit; n=1; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to nicotinic acetylcholine receptor alpha 7c subunit - Strongylocentrotus purpuratus Length = 257 Score = 63.3 bits (147), Expect = 7e-09 Identities = 38/133 (28%), Positives = 66/133 (49%), Gaps = 4/133 (3%) Frame = +2 Query: 236 ESESTVRILADLQMNWIDKRLSWSAGEW-GCSTWLVSSERLWRPDVVLL-NAAATTAGDY 409 E E + I ++ W D+ L W + G + VS +++W PD+ L N + Sbjct: 19 EMEQRITINGWRKLQWRDEFLGWDKETYDGIDSLEVSPDKIWLPDIKLYENIDKDFQSED 78 Query: 410 ALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDF-VIDKR 586 A+ A V+N+G V+W + IS+ + + +P D+QTCT FGS + D ++ D Sbjct: 79 AVNALVTNDGMVTWYTPMVISSSCKINVRYFPFDVQTCTLTFGSWAYTIDSLNLNYSDDA 138 Query: 587 IYSMF-ESXAWDV 622 ++F + WD+ Sbjct: 139 TQNVFLNNGVWDL 151 >UniRef50_UPI0000E47C59 Cluster: PREDICTED: similar to alpha-9 nicotinic acetylcholine receptor subunit precursor; n=1; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to alpha-9 nicotinic acetylcholine receptor subunit precursor - Strongylocentrotus purpuratus Length = 451 Score = 63.3 bits (147), Expect = 7e-09 Identities = 36/99 (36%), Positives = 51/99 (51%), Gaps = 3/99 (3%) Frame = +2 Query: 278 NWIDKRLSWSAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYALRARV--SNNGSVS 448 NW D+ + W +G T L ++SE +W PDVVL N AA D+ V +N G V+ Sbjct: 42 NWKDEFMMWDPAVYGNITDLKIASELVWMPDVVLYNNAAKEYKDFMKDEIVVITNEGQVN 101 Query: 449 WIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEM 565 W IS+ S+ ++ +P D Q C KFG H E+ Sbjct: 102 WAAPKIISSYCSINVNTFPFDEQQCPMKFGPWQHEGKEL 140 >UniRef50_Q4S866 Cluster: Chromosome 5 SCAF14709, whole genome shotgun sequence; n=1; Tetraodon nigroviridis|Rep: Chromosome 5 SCAF14709, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 215 Score = 63.3 bits (147), Expect = 7e-09 Identities = 29/99 (29%), Positives = 55/99 (55%), Gaps = 1/99 (1%) Frame = +2 Query: 269 LQMNWIDKRLSWSAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 445 + + W D +L WS E+ G + V S+R+WRPDVVL + + +A V ++G++ Sbjct: 45 VDVEWTDMKLRWSPEEYVGITIIRVPSDRIWRPDVVLYDNSDGRFEGTVTKAVVKHDGTI 104 Query: 446 SWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDE 562 +W + + ++ + +P D+Q C+ KFGS ++ + Sbjct: 105 TWTAPANYKSACTIDVTFFPFDLQNCSMKFGSWTYDGSQ 143 >UniRef50_Q9N4M3 Cluster: Acetylcholine receptor protein 6; n=1; Caenorhabditis elegans|Rep: Acetylcholine receptor protein 6 - Caenorhabditis elegans Length = 562 Score = 63.3 bits (147), Expect = 7e-09 Identities = 32/118 (27%), Positives = 59/118 (50%), Gaps = 2/118 (1%) Frame = +2 Query: 227 NIRESESTVRILADLQMNWIDKRLSWSAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAG 403 ++ E + + + L +W+D RLSW+ E+G T + E LW PD++L N A + Sbjct: 44 DVHEKDQVITLKGTLIHHWLDYRLSWNPDEFGNITLMHFPGEMLWLPDIILYNNAHGSPW 103 Query: 404 -DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFV 574 + VS G V+W + ++ ++ +P D+Q C KFGS + +++ + Sbjct: 104 VSETTQVHVSFEGRVTWQPPVVYDAFCNIDIEWYPYDLQICELKFGSWTYGGSQLNLI 161 >UniRef50_Q24352 Cluster: Gamma-aminobutyric acid receptor alpha-like precursor (GABA(A) receptor alpha-like and glycine receptor-like subunit of Drosophila); n=3; Diptera|Rep: Gamma-aminobutyric acid receptor alpha-like precursor (GABA(A) receptor alpha-like and glycine receptor-like subunit of Drosophila) - Drosophila melanogaster (Fruit fly) Length = 686 Score = 63.3 bits (147), Expect = 7e-09 Identities = 41/152 (26%), Positives = 69/152 (45%), Gaps = 7/152 (4%) Frame = +2 Query: 107 ECENATSLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESESTVRILADLQ 274 + N ++S ++D+LL YD PD + + + +R I E + T + + Sbjct: 102 QSNNHANISELLDNLLRGYDNSIRPDFGGPPATIEVDIMVRSMGPISEVDMTYSMDCYFR 161 Query: 275 MNWIDKRLSWSAGEWGCSTWLVSSERLWRPDVVLLNAAAT---TAGDYALRARVSNNGSV 445 +W+DKRL++ + + + R+W+PD N + T R+ NG V Sbjct: 162 QSWVDKRLAFEGAQDTLALSVSMLARIWKPDTYFYNGKQSYLHTITTPNKFVRIYQNGRV 221 Query: 446 SWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 541 + RL I M L ++P D+Q C KFGS Sbjct: 222 LYSSRLTIKAGCPMNLADFPMDIQKCPLKFGS 253 >UniRef50_Q9GP98 Cluster: Acetylcholine receptor protein 22; n=3; Caenorhabditis|Rep: Acetylcholine receptor protein 22 - Caenorhabditis elegans Length = 434 Score = 62.9 bits (146), Expect = 9e-09 Identities = 38/154 (24%), Positives = 73/154 (47%), Gaps = 7/154 (4%) Frame = +2 Query: 194 VVNLTLHLRHAN---IRESESTVRILADLQMNWIDKRLSWSAGEW-GCSTWLVSSERLWR 361 V+N+T+ + N + E ++IL +W D L+W EW G ++ ++W Sbjct: 60 VLNVTVQPQIYNLVEVNEQNEQIKILLWFPQSWKDDYLTWDPKEWNGIERIIIPKSQIWI 119 Query: 362 PDVVLLNAAATT--AGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKF 535 PD + N T ++ R R V + K +D++ P+S+ ++P D+Q C +F Sbjct: 120 PDGYIFNTVEETEPLENHNARVRYDGRVEVDFNKLVDLTCPMSVL--SFPFDVQLCALQF 177 Query: 536 GSRMHNSDEMDF-VIDKRIYSMFESXAWDVTDLS 634 GS + + + F V+D + ++ WD+ + Sbjct: 178 GSWSYQAHAISFNVLDTFVPKKSKNSEWDIVSFN 211 >UniRef50_Q2XWK5 Cluster: Nicotinic acetylcholine receptor subunit type H; n=1; Lymnaea stagnalis|Rep: Nicotinic acetylcholine receptor subunit type H - Lymnaea stagnalis (Great pond snail) Length = 450 Score = 62.9 bits (146), Expect = 9e-09 Identities = 46/174 (26%), Positives = 77/174 (44%), Gaps = 6/174 (3%) Frame = +2 Query: 131 SLMIDSLLATYDRE----SPPDSKIVVNLTLHLRHAN-IRESESTVRILADLQMNWIDKR 295 S ++ LL YDR P + V+ L L+ + E + ++ + W D R Sbjct: 25 SRLMRDLLTDYDRRVRPVQRPSDTVHVSFGLGLKALLFVDEKREYMETVSYMLTAWHDGR 84 Query: 296 LSWSAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVSWIKRLDIS 472 L W+ ++ G T + + LW PD+V + A + +G VSWI L + Sbjct: 85 LMWNMSQYAGIDTIKIPAVDLWTPDIVPYTSIDEDIHLMETMAVIYASGHVSWIPTLHLR 144 Query: 473 TPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDKRIYSMFESXAWDVTDLS 634 +P S+ L +P D Q C+ KF S ++ D ++ + A+DV+D S Sbjct: 145 SPCSVNLKYFPFDEQKCSIKFASYGYHGDHLNIT----YFGSTPEHAFDVSDYS 194 >UniRef50_Q8WSF7 Cluster: GABA A receptor alpha subunit; n=1; Aplysia californica|Rep: GABA A receptor alpha subunit - Aplysia californica (California sea hare) Length = 448 Score = 62.5 bits (145), Expect = 1e-08 Identities = 41/154 (26%), Positives = 71/154 (46%), Gaps = 7/154 (4%) Frame = +2 Query: 125 SLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESESTVRILADLQMNWIDK 292 ++S ++DSLL YD+ P + VN + LR I E + + W+D Sbjct: 33 NISQVLDSLLEGYDKRLRPGFGGEALTVNADISLRSMGPISELNMIYTLDCYFRQRWMDH 92 Query: 293 RLSWSAGEWGCSTWLVSSERLWRPDVVLLNAAAT---TAGDYALRARVSNNGSVSWIKRL 463 RL+ + + + ER+W PD V N + + R++ NG+V + +RL Sbjct: 93 RLAMNVSLENLTLGIKILERIWHPDTVFYNGQKSYLHAITSHNRFLRIAANGTVLFSQRL 152 Query: 464 DISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEM 565 I M +N+P D+Q C GS +++D++ Sbjct: 153 TIQATCRMHPENFPMDIQHCPLLIGSFAYSTDDV 186 >UniRef50_Q66T21 Cluster: Nicotinic acetylcholine receptor subunit alpha 9; n=4; Culicidae|Rep: Nicotinic acetylcholine receptor subunit alpha 9 - Anopheles gambiae (African malaria mosquito) Length = 406 Score = 62.5 bits (145), Expect = 1e-08 Identities = 43/170 (25%), Positives = 74/170 (43%), Gaps = 8/170 (4%) Frame = +2 Query: 149 LLATYD---RESPPDSKIVVNLTLHLRHANIRESESTVRILADLQMNWIDKRLSWSAGEW 319 LL YD R S + V + + H I E +ST+ + ++ +W D +L+W+ + Sbjct: 46 LLKGYDPSIRPSQHYNVTTVETGITITHVEINEIKSTLSVYGWMKFSWNDPKLTWNPASY 105 Query: 320 G-CSTWLVSSERLWRPDVVLL-NAAATTAGDYA-LRARVSNNGSVSWIKRLDISTPISMQ 490 G + +WRPDVVL NA + Y V + G V W+ + + Sbjct: 106 GNLNVVRWDPTIVWRPDVVLYNNAGGSDQHHYGDTNVLVYSEGKVLWVPPTEYHAFCELN 165 Query: 491 LDNWPNDMQTCTFKFGSRMHNSDEMDFVI--DKRIYSMFESXAWDVTDLS 634 + WP D Q C K GS + ++ I + +I ++ + W + +S Sbjct: 166 MRLWPFDYQKCIVKIGSWTFDGYMLNLTIGSEPQIETLVSNSEWKIAKIS 215 >UniRef50_A7RLP3 Cluster: Predicted protein; n=3; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 417 Score = 62.5 bits (145), Expect = 1e-08 Identities = 48/186 (25%), Positives = 82/186 (44%), Gaps = 15/186 (8%) Frame = +2 Query: 149 LLATYDR---ESPPDSKIVVNLTLH-LRHANIRESESTVRILADLQMNWIDKRLSWSAGE 316 LL YD+ S PD ++ +N +L ++ ++++ E V + MNWI+ L W + Sbjct: 20 LLDGYDKVVLPSEPD-RLALNFSLKFVQIMDVKDKEQLVSVECWYSMNWINSFLKWDKKK 78 Query: 317 W-GCSTWLVSSERLWRPDVVLLN----AAATTAG--DYALRARVSNNGSVSWIKRLDIST 475 + S +W PD+ L N T+ G + V + G W + + Sbjct: 79 YQNESRVFFDPSEIWVPDIALYNNGDDKVQTSGGRTKFLTNIVVEDTGKCVWSGPVTFTF 138 Query: 476 PISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDK----RIYSMFESXAWDVTDLSXAV 643 SM L WP D Q CT KFGS + + +F+I K + E+ W++ +++ A+ Sbjct: 139 TCSMALSRWPFDDQNCTMKFGSLSYGKN--NFIISKVKVSKSDDFIENSNWELKNITVAL 196 Query: 644 XXXXRG 661 G Sbjct: 197 QETDHG 202 >UniRef50_A2TM48 Cluster: Nicotinic acetylcholine receptor alpha 1 subunit; n=3; Aphidinae|Rep: Nicotinic acetylcholine receptor alpha 1 subunit - Sitobion avenae (English grain aphid) Length = 496 Score = 62.5 bits (145), Expect = 1e-08 Identities = 49/162 (30%), Positives = 74/162 (45%), Gaps = 12/162 (7%) Frame = +2 Query: 92 IASAAECENATSLSLMIDSLLATYDRESPPDSK----IVVNLTLHLRHA---NIRESEST 250 + SA C T + D LL+ Y+R P S ++V L L L N+++ T Sbjct: 12 LLSAVGCLCNTDAKRLYDDLLSNYNRLIRPVSNNTDTVLVKLGLRLSQLIELNLKDQILT 71 Query: 251 VRILADLQMNWIDKRLSWSAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYAL---- 415 + L+ W D + W E+G L V SE +W PD+VL N A G+Y + Sbjct: 72 TNVW--LEHEWADHKFIWEPLEYGGVKELYVPSEHIWLPDIVLYNNAD---GEYVVTTMT 126 Query: 416 RARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 541 +A + ++G V W + + + +P D QTC KFGS Sbjct: 127 KAVLHHSGKVMWTPPAIFKSSCEIDVRYFPFDQQTCFMKFGS 168 >UniRef50_Q2XWL0 Cluster: Nicotinic acetylcholine receptor subunit type C; n=1; Lymnaea stagnalis|Rep: Nicotinic acetylcholine receptor subunit type C - Lymnaea stagnalis (Great pond snail) Length = 506 Score = 62.1 bits (144), Expect = 2e-08 Identities = 40/136 (29%), Positives = 66/136 (48%), Gaps = 6/136 (4%) Frame = +2 Query: 179 PDSKIVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWSAGEWGCSTWL-VSSER 352 P K+ V L L L ++ E + I L+ W D RL W E+G L + S++ Sbjct: 54 PMKKLTVKLGLRLSQVLSVDERNQILTISVWLRQEWYDFRLKWEPSEYGGVNVLNIPSDQ 113 Query: 353 LWRPDVVLLNAAATTAGDYAL----RARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQT 520 LW+PD+VL N A GD+ + +A V++ G + W + + ++ +P D+Q Sbjct: 114 LWKPDLVLYNNA---DGDFQITLKTKAIVNHTGRIVWEPPAIYKSYCPIDVEYFPFDIQE 170 Query: 521 CTFKFGSRMHNSDEMD 568 C K S ++ E+D Sbjct: 171 CFLKISSWTYHGHELD 186 >UniRef50_P48180 Cluster: Acetylcholine receptor subunit alpha-type acr-16 precursor; n=3; Caenorhabditis|Rep: Acetylcholine receptor subunit alpha-type acr-16 precursor - Caenorhabditis elegans Length = 498 Score = 62.1 bits (144), Expect = 2e-08 Identities = 46/169 (27%), Positives = 75/169 (44%), Gaps = 7/169 (4%) Frame = +2 Query: 83 TCAIASAAECENATSLSLMIDSLLATYDRESPPDSKIVVNLTLHLRHA-----NIRESES 247 +CAI +A + L D L+ Y+ P + +T+HL+ A ++ E Sbjct: 9 SCAILAAPTLGSLQERRLYED-LMRNYNNLERPVANHSEPVTVHLKVALQQIIDVDEKNQ 67 Query: 248 TVRILADLQMNWIDKRLSWSAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGD-YALRA 421 V + A L W D L W E+G T + + ++W+PDV+L N+ T Y Sbjct: 68 VVYVNAWLDYTWNDYNLVWDKAEYGNITDVRFPAGKIWKPDVLLYNSVDTNFDSTYQTNM 127 Query: 422 RVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 568 V + G V W+ + + +P D Q C FKFGS ++ ++D Sbjct: 128 IVYSTGLVHWVPPGIFKISCKIDIQWFPFDEQKCFFKFGSWTYDGYKLD 176 >UniRef50_A7UFK6 Cluster: Nicotinic acetylcholine receptor alpha subunit; n=2; Ascaris suum|Rep: Nicotinic acetylcholine receptor alpha subunit - Ascaris suum (Pig roundworm) (Ascaris lumbricoides) Length = 513 Score = 61.7 bits (143), Expect = 2e-08 Identities = 40/148 (27%), Positives = 67/148 (45%), Gaps = 7/148 (4%) Frame = +2 Query: 137 MIDSLLATYDRES----PPDSKIVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLS 301 + D L+ Y++ P + + L L L ++ E + + L+ WIDK+LS Sbjct: 28 LYDDLMVNYNKHRRPAMSPHEPVTIKLKLRLSQIIDVHEIDQIMTYSVWLKQVWIDKKLS 87 Query: 302 WSAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAG-DYALRARVSNNGSVSWIKRLDIST 475 W + G S V E +W PD+VL N A + + +A + +G V+W + Sbjct: 88 WDPKNYGGVSVLYVPYEMIWVPDIVLYNNADSNYNITISTKATLHYSGEVTWEPPAIFKS 147 Query: 476 PISMQLDNWPNDMQTCTFKFGSRMHNSD 559 + + +P D Q C KFGS ++ D Sbjct: 148 MCQIDVRWFPFDEQKCHLKFGSWTYSED 175 >UniRef50_P54245 Cluster: Uncharacterized acetylcholine receptor-like protein F18G5.4 precursor; n=2; Caenorhabditis|Rep: Uncharacterized acetylcholine receptor-like protein F18G5.4 precursor - Caenorhabditis elegans Length = 615 Score = 61.7 bits (143), Expect = 2e-08 Identities = 35/128 (27%), Positives = 66/128 (51%), Gaps = 6/128 (4%) Frame = +2 Query: 269 LQMNWIDKRLSWSAGEWG-CSTWLVSSERLWRPDVVLLNAAATT--AGDYALRARVSNNG 439 L +NW+D RLSW+ W + R+W+PD++L+N A A + V+++G Sbjct: 165 LNINWMDPRLSWNESLWSEIKAIYIPHARIWKPDIILVNNAIREYYASLVSTDVMVTSDG 224 Query: 440 SVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVI--DK-RIYSMFESX 610 +V+W+ + +++ +P D Q C KF S H+ E++ + DK + S + Sbjct: 225 NVTWLFSALFRSSCPIRVRYYPFDDQQCDLKFASWSHDITEINLGLNTDKGDLSSYMNNS 284 Query: 611 AWDVTDLS 634 +D+ D++ Sbjct: 285 EFDLVDMT 292 >UniRef50_Q9U298 Cluster: Neuronal acetylcholine receptor subunit eat-2 precursor; n=1; Caenorhabditis elegans|Rep: Neuronal acetylcholine receptor subunit eat-2 precursor - Caenorhabditis elegans Length = 474 Score = 61.7 bits (143), Expect = 2e-08 Identities = 45/155 (29%), Positives = 73/155 (47%), Gaps = 7/155 (4%) Frame = +2 Query: 137 MIDSLLATYDRESPP--DSKIVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLS 301 ++ L YD P D + VN+ L L + ++ E + ++ Q W D +L Sbjct: 28 LLKDLREGYDPVERPVADHRKPVNVKLRLILQQLVDVDERNQVITLVVWNQYTWNDYKLR 87 Query: 302 WSAGEWGCSTWL-VSSERLWRPDVVLLNAAATTA-GDYALRARVSNNGSVSWIKRLDIST 475 WS E+G T L + LW+PD++L N+A + + VS+NG V + +S Sbjct: 88 WSPEEYGNITTLQIPHGTLWKPDILLFNSANEHFDASFPVHMVVSSNGDVLFAPPGIVSF 147 Query: 476 PISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVID 580 S+ + +P D Q C KFGS + ++D ID Sbjct: 148 SCSLSMTWFPYDQQVCYLKFGSWTYGK-KLDLQID 181 >UniRef50_A7S622 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 299 Score = 61.3 bits (142), Expect = 3e-08 Identities = 38/154 (24%), Positives = 71/154 (46%), Gaps = 10/154 (6%) Frame = +2 Query: 137 MIDSLLATYDRESPP----DSKIVVNLTLHLRH-ANIRESESTVRILADLQMNWIDKRLS 301 ++ L Y + + P D+ +V L+ +++++E ++I+ M W + L+ Sbjct: 4 LLRDLFQNYSKYARPSIESDAPAIVTFRAKLKQIVDLKDNEQLLKIILYNYMQWENPILT 63 Query: 302 WSAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGD----YALRARVSNNGSVSWIKRLD 466 W ++G + V+ E +W PD+V+ N+A G Y + NG+ W+ Sbjct: 64 WDPRDYGGVQEINVAPEEVWVPDIVIYNSAEDVLGGLTHKYKTDVVIQANGTNIWLAPAM 123 Query: 467 ISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 568 T + + +P D Q C KFGS H+S +D Sbjct: 124 FLTTCQLDVRYFPFDEQKCLLKFGSWTHDSSRLD 157 >UniRef50_UPI0000E49402 Cluster: PREDICTED: similar to alpha 10 subunit of nicotinic acetylcholine receptor; n=1; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to alpha 10 subunit of nicotinic acetylcholine receptor - Strongylocentrotus purpuratus Length = 473 Score = 60.9 bits (141), Expect = 4e-08 Identities = 32/98 (32%), Positives = 52/98 (53%), Gaps = 2/98 (2%) Frame = +2 Query: 281 WIDKRLSWSAGEWGCSTWL-VSSERLWRPDVVLL-NAAATTAGDYALRARVSNNGSVSWI 454 W D L W+ ++G +T L V E +WRPD+VL NA ++ G A +S++G V W Sbjct: 80 WTDSNLKWNPADYGDTTVLIVPIETIWRPDIVLFTNADSSFNGMMMTSASISHDGIVRWN 139 Query: 455 KRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 568 + + + +P D Q C+ KFGS ++ ++D Sbjct: 140 APAIYQSTCKIDITYFPFDEQHCSLKFGSWAYHGFQID 177 >UniRef50_O16926 Cluster: Acetylcholine receptor protein 15; n=2; Caenorhabditis|Rep: Acetylcholine receptor protein 15 - Caenorhabditis elegans Length = 479 Score = 60.9 bits (141), Expect = 4e-08 Identities = 46/172 (26%), Positives = 80/172 (46%), Gaps = 8/172 (4%) Frame = +2 Query: 137 MIDSLLATYDRESPP--DSK--IVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLS 301 +I+ L++ Y RE P DS +VV+L + L+ N+ E E + + A L+ W D+ L Sbjct: 25 LINDLMSGYVREERPTLDSSKPVVVSLGVFLQQIINLSEKEEQLEVNAWLKFQWRDENLR 84 Query: 302 WSAGEWGCSTWLVSS-ERLWRPDVVLLNAAATTA-GDYALRARVSNNGSVSWIKRLDIST 475 W + T L + LW PD++L N+ + Y + + G+++W+ Sbjct: 85 WEPTAYENVTDLRHPPDALWTPDILLYNSVDSEFDSSYKVNLVNYHTGNINWMPPGIFKV 144 Query: 476 PISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDKRIYSMF-ESXAWDVTD 628 + + +P D Q C FKFGS + D++ +S F + W + D Sbjct: 145 SCKLDIYWFPFDEQVCYFKFGSWTYTRDKIQLEKGDFDFSEFIPNGEWIIID 196 >UniRef50_Q9UGM1 Cluster: Neuronal acetylcholine receptor subunit alpha-9 precursor; n=30; Euteleostomi|Rep: Neuronal acetylcholine receptor subunit alpha-9 precursor - Homo sapiens (Human) Length = 479 Score = 60.9 bits (141), Expect = 4e-08 Identities = 45/184 (24%), Positives = 83/184 (45%), Gaps = 10/184 (5%) Frame = +2 Query: 101 AAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHANIRESESTVRILAD-- 268 AAE + + + L Y P D+ V+N+TL + + I++ + +IL Sbjct: 22 AAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQITLSQIKDMDERNQILTAYL 81 Query: 269 -LQMNWIDKRLSWSAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGD-YALRARVSNNG 439 ++ W D L+W ++ G + + S+ +WRPD+VL N A + + + +G Sbjct: 82 WIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKADDESSEPVNTNVVLRYDG 141 Query: 440 SVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDF--VIDKRIYSMF-ESX 610 ++W + + + +P D Q C FGS +N +++D +D S F E Sbjct: 142 LITWDAPAITKSSCVVDVTYFPFDNQQCNLTFGSWTYNGNQVDIFNALDSGDLSDFIEDV 201 Query: 611 AWDV 622 W+V Sbjct: 202 EWEV 205 >UniRef50_UPI00015B4DDF Cluster: PREDICTED: similar to neurotransmitter gated ion channel; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to neurotransmitter gated ion channel - Nasonia vitripennis Length = 461 Score = 60.5 bits (140), Expect = 5e-08 Identities = 39/156 (25%), Positives = 70/156 (44%), Gaps = 5/156 (3%) Frame = +2 Query: 116 NATSLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHANIRESESTVRILADLQMNWI 286 N T + LLA YD+ + P + V++ L+++ + + + + + M W Sbjct: 38 NETWTDRLKQHLLAKYDKFARPAQHWNTTTVSVKLNVQTVEVDDMTNVMAANVWVVMTWN 97 Query: 287 DKRLSWSAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALR-ARVSNNGSVSWIKR 460 D +L+W++ E+ G + + +W PD+ LLN+AA Y R VS G V W+ Sbjct: 98 DDKLTWNSSEYSGLKQVNLGAHEIWLPDIYLLNSAAHGMEYYGDRHCVVSEQGVVLWVTP 157 Query: 461 LDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 568 + WP +M TC S ++ ++D Sbjct: 158 TIFHGYCHLDFTFWPFEMNTCRLSLSSWTYDGTQVD 193 >UniRef50_Q7T2S3 Cluster: Nicotinic acetylcholine receptor alpha 4 subunit; n=2; Tetraodontidae|Rep: Nicotinic acetylcholine receptor alpha 4 subunit - Fugu rubripes (Japanese pufferfish) (Takifugu rubripes) Length = 622 Score = 60.5 bits (140), Expect = 5e-08 Identities = 44/179 (24%), Positives = 86/179 (48%), Gaps = 15/179 (8%) Frame = +2 Query: 137 MIDSLLATYDRESPPDSKIVVNLTLHL-----RHANIRESESTVRILADLQMNWIDKRLS 301 ++ L A Y++ S P + +H + ++ E + ++ W D +L Sbjct: 14 LLQDLFAHYNKLSRPVENTTDTVLVHFGLSIAQLIDVDEKNQMMTTNVWVKQEWNDYKLR 73 Query: 302 WSAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNGSVSWIKRLD 466 W+ E+ T + + SE +WRPD+VL N A GD+A+ +A++ +G + W+ Sbjct: 74 WNPEEYENVTSIRIPSEIIWRPDIVLYNNAD---GDFAVTHLTKAQLFYDGRIKWMPPAI 130 Query: 467 ISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFV-----IDKRIYSMFESXAWDVTD 628 + S+ + +P D Q+C KFGS ++ ++D + +D+ Y +ES W + + Sbjct: 131 YKSSCSIDVTFFPFDQQSCKMKFGSWTYDRAKIDLISMASDVDQMDY--WESGEWVIVN 187 >UniRef50_A7RLM4 Cluster: Predicted protein; n=2; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 300 Score = 60.5 bits (140), Expect = 5e-08 Identities = 39/156 (25%), Positives = 75/156 (48%), Gaps = 8/156 (5%) Frame = +2 Query: 161 YDRESPPDSK--IVVNLTLHLRHANIRESESTVRIL---ADLQMNWIDKRLSWSAGEW-G 322 YD + P + + +N+T + I E ++L +++ +W+D L+W+ ++ G Sbjct: 3 YDPQVRPSDRADMPINITFGISLNEIYELTDRTQLLITKVEIRESWVDTSLAWNKSDFEG 62 Query: 323 CSTWLVSSERLWRPDVVLLNAAATTAGDYALR--ARVSNNGSVSWIKRLDISTPISMQLD 496 + ++ E +WRPD+VL N A GD R A V+++G VS + T + Sbjct: 63 LAKIVLRPESIWRPDIVLYNNAGEDFGDGQTRTNAVVTSDGLVSMTIPSILKTSCKIDAT 122 Query: 497 NWPNDMQTCTFKFGSRMHNSDEMDFVIDKRIYSMFE 604 +P D Q+C FGS ++ + + ++ + E Sbjct: 123 RYPFDKQSCPMIFGSWTYDGNLLSIKMESHSADLSE 158 >UniRef50_P07510 Cluster: Acetylcholine receptor subunit gamma precursor; n=31; Gnathostomata|Rep: Acetylcholine receptor subunit gamma precursor - Homo sapiens (Human) Length = 517 Score = 60.5 bits (140), Expect = 5e-08 Identities = 43/157 (27%), Positives = 74/157 (47%), Gaps = 8/157 (5%) Frame = +2 Query: 137 MIDSLLATYDRESPPDSKI--VVNLTLHLRHANI---RESESTVRILADLQMNWIDKRLS 301 ++ L+ YD P + VVN++L L N+ E E + ++M W D RL Sbjct: 29 LLADLMQNYDPNLRPAERDSDVVNVSLKLTLTNLISLNEREEALTTNVWIEMQWCDYRLR 88 Query: 302 WSAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARV--SNNGSVSWIKRLDIS 472 W ++ G V S +WRPD+VL N + AL V S +G + W+ Sbjct: 89 WDPRDYEGLWVLRVPSTMVWRPDIVLENNVDGVF-EVALYCNVLVSPDGCIYWLPPAIFR 147 Query: 473 TPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDK 583 + S+ + +P D Q C+ F S+ ++++E+D + + Sbjct: 148 SACSISVTYFPFDWQNCSLIFQSQTYSTNEIDLQLSQ 184 >UniRef50_UPI0000E49844 Cluster: PREDICTED: similar to nicotinic acetylcholine receptor alpha2 subunit; n=1; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to nicotinic acetylcholine receptor alpha2 subunit - Strongylocentrotus purpuratus Length = 570 Score = 60.1 bits (139), Expect = 7e-08 Identities = 46/190 (24%), Positives = 90/190 (47%), Gaps = 13/190 (6%) Frame = +2 Query: 92 IASAAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHANIRESESTVRILA 265 +A A C ++ + + L Y+R P ++ V+++ L + + + + +I+ Sbjct: 67 LAFAQGCTSSEAEERLFTKLFYKYNRLIRPVENNSEVLDVNFRLTMSQLIDVDEKNQIMT 126 Query: 266 D---LQMNWIDKRLSWSAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYAL----RA 421 L+ W+D +L W+ E+ S V S+ +W PD+VL N A G+Y + +A Sbjct: 127 TNVWLKQLWMDYKLQWNPAEYDNISILRVPSKMIWTPDLVLYNNAD---GNYEVTLMAKA 183 Query: 422 RVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFV---IDKRIY 592 V ++G+V W+ + + + +P D Q C KFGS ++ +D + D + Sbjct: 184 LVYSDGTVYWLPPAIYKSSCKINVRYFPFDEQFCPMKFGSWTYDGSLIDLIPSSNDVDLE 243 Query: 593 SMFESXAWDV 622 ++S WD+ Sbjct: 244 DYWQSGEWDI 253 >UniRef50_UPI0000E47C58 Cluster: PREDICTED: similar to nicotinic acetylcholine receptor beta 5 subunit; n=1; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to nicotinic acetylcholine receptor beta 5 subunit - Strongylocentrotus purpuratus Length = 477 Score = 60.1 bits (139), Expect = 7e-08 Identities = 32/102 (31%), Positives = 50/102 (49%), Gaps = 3/102 (2%) Frame = +2 Query: 269 LQMNWIDKRLSWSAGEWG-CSTWLVSSERLWRPDVVLLNAAATTAGDYALRA--RVSNNG 439 L + W D L W + + ++ + +W PD+ L N A + DYA + V + G Sbjct: 58 LDVRWHDDYLVWEPTRYNNVKNFKITRDDVWMPDLWLYNNAGSRYEDYAAHSICSVYHTG 117 Query: 440 SVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEM 565 V W I T +M + N+P D+QTCT FG H ++E+ Sbjct: 118 KVVWQSPTIIKTHCTMDVTNFPFDVQTCTVTFGPWQHGANEI 159 >UniRef50_Q23022 Cluster: Acetylcholine receptor subunit alpha-type unc-38 precursor; n=9; Chromadorea|Rep: Acetylcholine receptor subunit alpha-type unc-38 precursor - Caenorhabditis elegans Length = 511 Score = 60.1 bits (139), Expect = 7e-08 Identities = 38/142 (26%), Positives = 65/142 (45%), Gaps = 7/142 (4%) Frame = +2 Query: 137 MIDSLLATYDRE----SPPDSKIVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLS 301 + D L+ Y+R + P+ + + L L L ++ E + + L+ WID++LS Sbjct: 30 LYDDLMVNYNRHRRPSTSPNKPLTIKLKLRLSQIIDVHEIDQIMTCSVWLKQTWIDRKLS 89 Query: 302 WSAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAG-DYALRARVSNNGSVSWIKRLDIST 475 W + G + V E +W PD+VL N A + + +A + G V+W + Sbjct: 90 WDPVNYGGVNVLYVPYEMIWVPDIVLYNNADSNYNITISTKATLHYTGEVTWEPPAIFKS 149 Query: 476 PISMQLDNWPNDMQTCTFKFGS 541 + + +P D Q C KFGS Sbjct: 150 MCQIDVRWFPFDEQQCHLKFGS 171 >UniRef50_Q2XWK3 Cluster: Nicotinic acetylcholine receptor subunit type K; n=1; Lymnaea stagnalis|Rep: Nicotinic acetylcholine receptor subunit type K - Lymnaea stagnalis (Great pond snail) Length = 501 Score = 59.7 bits (138), Expect = 9e-08 Identities = 42/157 (26%), Positives = 72/157 (45%), Gaps = 10/157 (6%) Frame = +2 Query: 137 MIDSLLATYDRESP---P----DSKIVVNLTLHL-RHANIRESESTVRILADLQMNWIDK 292 +I +LLA Y R P + I +N + L + ++ E + + + W D Sbjct: 31 LIKNLLARYKRRGTYARPVKEYNDSITINFNMQLIQIMDLDEKNQVLTLNVWDRYIWHDL 90 Query: 293 RLSWSAGEWG-CSTWLVSSERLWRPDVVLLNAAATTAGDYA-LRARVSNNGSVSWIKRLD 466 L+W+ + G V S ++W PD+ L N A + R V +NG V W+ + Sbjct: 91 HLTWNETKHGGVKNIRVPSNKIWIPDLKLYNYADERLAERRDARCVVESNGKVLWMPQAI 150 Query: 467 ISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVI 577 + + + +P D+Q CT KFGS HN + +D ++ Sbjct: 151 YKSSCEIDVATFPFDIQNCTLKFGSWTHNGNLIDLMV 187 >UniRef50_Q65XS8 Cluster: Acetylcholine receptor protein 25; n=2; Caenorhabditis elegans|Rep: Acetylcholine receptor protein 25 - Caenorhabditis elegans Length = 544 Score = 59.3 bits (137), Expect = 1e-07 Identities = 39/133 (29%), Positives = 65/133 (48%), Gaps = 3/133 (2%) Frame = +2 Query: 191 IVVNLTLHLRH-ANIRESESTVRILADLQMNWIDKRLSWSAGEWGCSTWL-VSSERLWRP 364 ++V + L L+ ++ E V + A L+ +W+D L W ++G T L +LW P Sbjct: 51 VMVKMGLVLQQIVDVDEKNQVVDVNAWLKFSWVDYSLKWKPEDYGGVTDLRFRKGQLWTP 110 Query: 365 DVVLLNAAATTAGD-YALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 541 DV++ N+A YA V NG V+W+ +Q+ +P D+Q C KFGS Sbjct: 111 DVLMYNSADPQFDSRYASNLLVYPNGLVNWMPPGLYRLSCKIQVVWFPFDVQECFLKFGS 170 Query: 542 RMHNSDEMDFVID 580 + +++ ID Sbjct: 171 WTFDGTKLNLEID 183 >UniRef50_A7SI11 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 404 Score = 59.3 bits (137), Expect = 1e-07 Identities = 47/177 (26%), Positives = 81/177 (45%), Gaps = 14/177 (7%) Frame = +2 Query: 134 LMIDSLLATYDRESPP---DSKIVVNLTLHLRHANIRESESTVRILAD---LQMNWIDKR 295 L+ D L +D + P + V+N T+ L+ I E ++ + ++ W D + Sbjct: 5 LVTDLLAGYHDSQRPALDNNEPTVINFTIRLQQ--IYELNGQLQKMVSSVWIEQAWWDHK 62 Query: 296 LSWSAGEWGCSTWLVSSER--LWRPDVVLLNAAATTAGDYALR----ARVSNNGSVSWIK 457 L W ++G +V ER +W PDVVLLN A ++ + V +NG V W+ Sbjct: 63 LQWDQSKYGGIKEVVLPERGVIWVPDVVLLNNAEKSSMGKPVNEGNPVLVESNGVVRWLA 122 Query: 458 RLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDF-VIDKRIYSMF-ESXAWDV 622 + + + M + ++P D Q C KF S + E+ +D + + ES WD+ Sbjct: 123 PVVLKSRCKMDVRSYPFDEQYCGLKFASWTGSQSELRLDAMDNDVRQNYSESSEWDL 179 >UniRef50_UPI0000E464AB Cluster: PREDICTED: similar to nicotinic acetylcholine receptor; n=1; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to nicotinic acetylcholine receptor - Strongylocentrotus purpuratus Length = 528 Score = 58.8 bits (136), Expect = 2e-07 Identities = 35/128 (27%), Positives = 59/128 (46%), Gaps = 8/128 (6%) Frame = +2 Query: 269 LQMNWIDKRLSWSAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYALR----ARVSN 433 ++ W D RL W ++G T + + LW+PD+VL N G YA+ +V Sbjct: 68 VRQRWEDYRLVWDPADYGNITMVHIPIFLLWKPDIVLYN---NVGGSYAITMLTMTQVYP 124 Query: 434 NGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDKRIYSM---FE 604 NG+V W + + + ++P D Q C KFGS H+ ++D + +E Sbjct: 125 NGTVDWFPPAVYRSSCPINIHDFPFDEQRCPLKFGSWTHDYSKIDLQPISEFVGLERFWE 184 Query: 605 SXAWDVTD 628 + WD+ + Sbjct: 185 NQEWDIAE 192 >UniRef50_Q7Z6B2 Cluster: 5-hydroxytryptamine serotonin receptor 3E; n=30; Theria|Rep: 5-hydroxytryptamine serotonin receptor 3E - Homo sapiens (Human) Length = 471 Score = 58.8 bits (136), Expect = 2e-07 Identities = 34/140 (24%), Positives = 66/140 (47%), Gaps = 9/140 (6%) Frame = +2 Query: 269 LQMNWIDKRLSWSAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 445 L+M W + +SW+ E G + ++++ LW PD+ ++ L A VSN G + Sbjct: 106 LEMVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEGRI 165 Query: 446 SWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDKRIYSMFES------ 607 + K + + + ++ + +P D Q CT F S ++ D M ++K ++ + ++ Sbjct: 166 RYKKPMKVDSICNLDIFYFPFDQQNCTLTFSSFLYTVDSMLLDMEKEVWEITDASRNILQ 225 Query: 608 --XAWDVTDLSXAVXXXXRG 661 W++ LS A RG Sbjct: 226 THGEWELLGLSKATAKLSRG 245 >UniRef50_Q23355 Cluster: Putative uncharacterized protein acr-8; n=2; Caenorhabditis|Rep: Putative uncharacterized protein acr-8 - Caenorhabditis elegans Length = 537 Score = 58.4 bits (135), Expect = 2e-07 Identities = 35/102 (34%), Positives = 49/102 (48%), Gaps = 2/102 (1%) Frame = +2 Query: 269 LQMNWIDKRLSWSAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYALR-ARVSNNGS 442 L+M W D RL W G WG L V +++W PD++L N A + A V NG Sbjct: 77 LEMQWFDYRLMWDPGRWGKIRKLHVPVDQIWIPDILLYNNADGEPHITIMSDAIVYYNGL 136 Query: 443 VSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 568 V W + S+ ++ +P D QTC KFG +N +D Sbjct: 137 VVWKPPSIYKSFCSIDIEYFPYDTQTCWMKFGGWTYNGFLLD 178 >UniRef50_O46132 Cluster: Nicotinic acetylcholine receptor, alpha1 subunit; n=1; Locusta migratoria|Rep: Nicotinic acetylcholine receptor, alpha1 subunit - Locusta migratoria (Migratory locust) Length = 559 Score = 58.0 bits (134), Expect = 3e-07 Identities = 30/102 (29%), Positives = 51/102 (50%), Gaps = 2/102 (1%) Frame = +2 Query: 269 LQMNWIDKRLSWSAGEWG-CSTWLVSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 442 ++ W D +L W+ ++G T V SE +W PD+VL N + A +A + + G Sbjct: 37 VEQEWNDYKLKWNPDDYGGVDTLHVPSEHIWLPDIVLTNNSEGNFEVTLATKATIYHQGL 96 Query: 443 VSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 568 V W + + ++ +P D QTC KFGS ++ ++D Sbjct: 97 VEWKPPAIYKSSCEIDVEYFPFDEQTCVLKFGSWTYDGFKVD 138 >UniRef50_P25162 Cluster: Acetylcholine receptor subunit beta-like 2 precursor; n=7; Diptera|Rep: Acetylcholine receptor subunit beta-like 2 precursor - Drosophila melanogaster (Fruit fly) Length = 519 Score = 58.0 bits (134), Expect = 3e-07 Identities = 44/154 (28%), Positives = 70/154 (45%), Gaps = 10/154 (6%) Frame = +2 Query: 137 MIDSLLATYDRESPPDSKIVVNLT--LHLRHANIRESESTVRILAD---LQMNWIDKRLS 301 + D LL+ Y+R P LT L L+ + + E +++ ++ W D +L Sbjct: 33 LYDDLLSNYNRLIRPVVNNTETLTVWLGLKLSQLIEVNLKNQVMTTNLWVKQRWFDYKLR 92 Query: 302 WSAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNGSVSWIKRLD 466 W E+G L V SE +W PD+VL N G+Y + +A + G V W Sbjct: 93 WDPEEYGGVEQLYVPSEHIWVPDIVLYN---NWDGNYEVTLMTKATLKYTGEVFWEPPAI 149 Query: 467 ISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 568 + M ++ +P D Q C KFGS +N ++D Sbjct: 150 YKSSCEMNVEYFPYDEQICFMKFGSWTYNGAQVD 183 >UniRef50_UPI00015B5C6B Cluster: PREDICTED: similar to nicotinic acetylcholine receptor alpha9 subunit; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to nicotinic acetylcholine receptor alpha9 subunit - Nasonia vitripennis Length = 304 Score = 57.6 bits (133), Expect = 3e-07 Identities = 34/122 (27%), Positives = 60/122 (49%), Gaps = 6/122 (4%) Frame = +2 Query: 275 MNWIDKRLSWSAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYAL---RARVSNNGS 442 MNW D L+W+ ++ G T V S+ LW PD+ + N + G + +S++G Sbjct: 95 MNWTDPHLTWNPEDFEGLDTIQVPSDSLWTPDIAVHNTHDASKGKPGIAKTNCGLSHDGH 154 Query: 443 VSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD-FVIDKRIYS-MFESXAW 616 V+ + + ST ++P D+Q CT S +++DE+ ++ K + S + W Sbjct: 155 VTCVPAVKYSTNCLPDFTDYPYDLQVCTIDLASWAYSTDEIQLLMLRKPVTSDLSPGQEW 214 Query: 617 DV 622 DV Sbjct: 215 DV 216 >UniRef50_Q9GQ00 Cluster: Serotonin-gated chloride channel; n=4; Caenorhabditis|Rep: Serotonin-gated chloride channel - Caenorhabditis elegans Length = 489 Score = 57.6 bits (133), Expect = 3e-07 Identities = 44/162 (27%), Positives = 78/162 (48%), Gaps = 10/162 (6%) Frame = +2 Query: 113 ENATSLSLMIDSLLATYDRESPP-DSKIVVNLTLHLRH-ANIRESESTVRILADLQMNWI 286 E A S +++++++ Y + P + + VN+ +H++ ++ E S I W Sbjct: 29 EGAWSEGKIMNTIMSNYTKMLPDAEDSVQVNIEIHVQDMGSLNEISSDFEIDILFTQLWH 88 Query: 287 DKRLSWSAGEWGCSTWLVSSERL----WRPDVVLLNAAATT---AGDYALRARVSNNGSV 445 D LS+ A C + RL W P+ ++N+ TT + + + NG+V Sbjct: 89 DSALSF-AHLPACKRNITMETRLLPKIWSPNTCMINSKRTTVHASPSENVMVILYENGTV 147 Query: 446 SWIK-RLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 568 WI RL + +P ++ L +P D QTC F S HNS+E++ Sbjct: 148 -WINHRLSVKSPCNLDLRQFPFDTQTCILIFESYSHNSEEVE 188 >UniRef50_Q29ND1 Cluster: GA17977-PA; n=3; Schizophora|Rep: GA17977-PA - Drosophila pseudoobscura (Fruit fly) Length = 531 Score = 57.6 bits (133), Expect = 3e-07 Identities = 40/155 (25%), Positives = 74/155 (47%), Gaps = 7/155 (4%) Frame = +2 Query: 137 MIDSLLATYDRESPP----DSKIVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLS 301 +++ LL+TY+ P + V L L+ ++ E + L + W D L Sbjct: 14 LLNHLLSTYNTLERPVANESEPLEVKFGLTLQQIIDVDEKNQLLITNLWLSLEWNDYNLR 73 Query: 302 WSAGEWGCSTWL-VSSERLWRPDVVLLNAAATTA-GDYALRARVSNNGSVSWIKRLDIST 475 W+ E+G L ++ +LW+PDV++ N+A G Y V +NGS ++ + Sbjct: 74 WNETEYGGVKDLRITPNKLWKPDVLMYNSADEGFDGTYHTNIVVKHNGSCLYVPPGIFKS 133 Query: 476 PISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVID 580 + + +P D Q C KFGS ++ +++D V++ Sbjct: 134 TCKIDITWFPFDDQHCEMKFGSWTYDGNQLDLVLN 168 >UniRef50_A7SW63 Cluster: Predicted protein; n=3; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 324 Score = 57.6 bits (133), Expect = 3e-07 Identities = 36/154 (23%), Positives = 76/154 (49%), Gaps = 10/154 (6%) Frame = +2 Query: 137 MIDSLLATYDRESPP----DSKIVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLS 301 ++ LL Y +++ P + + + L + LR ++ E + + I ++ W D L Sbjct: 4 LLKYLLQNYSKDARPVLNVNDPVQLKLGIMLRQVIDLNERDQILTINVWIRQYWKDHLLK 63 Query: 302 WSAGEWG-CSTWLVSSERLWRPDVVLLNAAATTAGDYALRAR----VSNNGSVSWIKRLD 466 W+ ++G + ++ +R+W+PDV+L N G + V+++GS +W+ Sbjct: 64 WNPDDFGGIKSINIAPDRVWKPDVLLYNRTDLRFGSLNNKIDTNVIVNHDGSTTWLAPAI 123 Query: 467 ISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 568 I + + + +P D+Q+C FGS H+ ++D Sbjct: 124 IKSECKIDVRFFPFDVQSCELTFGSWTHDGLKID 157 >UniRef50_A7RK99 Cluster: Predicted protein; n=2; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 446 Score = 57.6 bits (133), Expect = 3e-07 Identities = 46/188 (24%), Positives = 81/188 (43%), Gaps = 14/188 (7%) Frame = +2 Query: 113 ENATSLSLMIDSLLATYDRESPPDS---KIVVNLTLHLRHANIRESESTVRIL---ADLQ 274 +NA +L D LL YDR P S + ++ LT L+ + + ++ +++ A + Sbjct: 24 QNAVRKALRAD-LLKDYDRIVGPVSHSPRSLLELTFVLKITKLNKVDTKNQVISVNAWVF 82 Query: 275 MNWIDKRLSWSAGEWGCSTWLVSSERLWRPDVVLLNAA---ATTAGDYAL---RARVSNN 436 W D L W ++ S + +W PDV L+N AG L V + Sbjct: 83 QQWKDPSLQWDKAKYNLHKTRFSPKEIWVPDVSLINNGDKLVHVAGGAELFNADTVVRQS 142 Query: 437 GSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDKR--IYSMFESX 610 G V WI + ++ ++++ WP D Q CT F S + E+ +D + Sbjct: 143 GKVDWIAQASFTSTCNLRVRFWPMDDQFCTLTFSSWTYTESEIALKMDNSGLTTGHLSNN 202 Query: 611 AWDVTDLS 634 WD+ +++ Sbjct: 203 EWDILNIT 210 >UniRef50_UPI0000E48B7E Cluster: PREDICTED: similar to neuronal nicotinic acetylcholine receptor alpha3 subunit; n=1; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to neuronal nicotinic acetylcholine receptor alpha3 subunit - Strongylocentrotus purpuratus Length = 525 Score = 57.2 bits (132), Expect = 5e-07 Identities = 31/123 (25%), Positives = 63/123 (51%), Gaps = 7/123 (5%) Frame = +2 Query: 281 WIDKRLSWSAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAG-DYALRARVSNNGSVSWI 454 W D L W+ ++ G + + +E +WRPD++L N A + + A V G+V+W+ Sbjct: 89 WQDHHLMWNPEDYEGITELHIPAENIWRPDILLYNNANGNFDVQFLVNAIVKYTGTVTWL 148 Query: 455 KRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDF-----VIDKRIYSMFESXAWD 619 + ++ ++ +P D Q+C KFG H++ ++D V+D+ Y + + W+ Sbjct: 149 PPAIYKSSCTIDIEYFPFDEQSCKMKFGPWTHDTLKIDMASSNDVVDQEDY--WPNGEWE 206 Query: 620 VTD 628 + + Sbjct: 207 IVE 209 >UniRef50_A0EIZ9 Cluster: Nicotinic acetylcholine receptor beta2 subunit; n=1; Apis mellifera|Rep: Nicotinic acetylcholine receptor beta2 subunit - Apis mellifera (Honeybee) Length = 427 Score = 57.2 bits (132), Expect = 5e-07 Identities = 42/162 (25%), Positives = 76/162 (46%), Gaps = 10/162 (6%) Frame = +2 Query: 110 CENATSLSLMIDS---LLATYDRESPPDSKIV--VNLTLHLRHANIRESESTVRILADLQ 274 C++ TS S + L YDR+ P+ K ++ L ++H N+ E TV L+ Sbjct: 28 CKDITSTSALYRLKLYLFCDYDRDIIPEQKNATKIDFGLSIQHYNVDEYSHTVDFHVMLK 87 Query: 275 MNWIDKRLSWSAGEW-GCSTWLVSSERLWRPDVVL--LNAAATTAGDYALRARVSNNGSV 445 + W L+W + E+ ++ V S +W PD+V+ + + ++ V N+G++ Sbjct: 88 LMWEQSHLTWKSSEFDSINSIRVKSYEIWVPDIVMHSVTSVGIDLEMPSVECIVFNSGTI 147 Query: 446 SWIKRLDISTPISMQLDN--WPNDMQTCTFKFGSRMHNSDEM 565 + TP+ + D+ WP D+ CT S H S+E+ Sbjct: 148 LCVP-FTTYTPV-CEYDHTWWPYDILNCTIHIASWSHGSNEI 187 >UniRef50_Q60S81 Cluster: Neuronal acetylcholine receptor subunit eat-2 precursor; n=1; Caenorhabditis briggsae|Rep: Neuronal acetylcholine receptor subunit eat-2 precursor - Caenorhabditis briggsae Length = 477 Score = 57.2 bits (132), Expect = 5e-07 Identities = 43/155 (27%), Positives = 72/155 (46%), Gaps = 7/155 (4%) Frame = +2 Query: 137 MIDSLLATYDRESPP--DSKIVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLS 301 ++ L YD P D VN+ L L + ++ E + ++ Q W D ++ Sbjct: 26 LLKDLREGYDPMERPVSDHMKPVNVKLRLILQQLVDVDEKNQVITLVVWTQYTWNDYKMK 85 Query: 302 WSAGEWGCSTWL-VSSERLWRPDVVLLNAAATTA-GDYALRARVSNNGSVSWIKRLDIST 475 WS E+G T L + LW+PD++L N+A + + VSN+G+V + + Sbjct: 86 WSPEEYGNITSLQIPFGTLWKPDILLFNSANEHFDSSFPVNMVVSNDGNVLFAPPGIMQF 145 Query: 476 PISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVID 580 S+ + +P D Q C KFGS + ++D ID Sbjct: 146 SCSLSMTWFPYDEQVCYLKFGSWTYGK-KLDLRID 179 >UniRef50_UPI0000D55E50 Cluster: PREDICTED: similar to AcetylCholine Receptor family member (acr-21); n=3; Endopterygota|Rep: PREDICTED: similar to AcetylCholine Receptor family member (acr-21) - Tribolium castaneum Length = 649 Score = 56.8 bits (131), Expect = 6e-07 Identities = 37/162 (22%), Positives = 73/162 (45%), Gaps = 8/162 (4%) Frame = +2 Query: 107 ECENATSLSLMIDSLLATYDRESPPDSKIVVNLT----LHLRHA-NIRESESTVRILADL 271 EC+ + + ++ L+ YD P + LT + L H ++ E + + Sbjct: 13 ECQGDENEARLMRHLMTNYDAAVRPVENSSLPLTVIFGISLHHIIDVDEKNQILTTNCWI 72 Query: 272 QMNWIDKRLSWSAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARV--SNNGS 442 WID L W+A ++ G + R+WRPD++L N A + V S++G Sbjct: 73 TQAWIDHHLRWNASDFAGIKVIRIPYTRVWRPDLILYNNADPQFQSSVINTNVIVSSSGE 132 Query: 443 VSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 568 V W+ + + ++ +P D+Q+C K+ S ++ +++ Sbjct: 133 VLWLSHGIYRSSCDINVEYFPFDLQSCHMKWASWTYDGYQVE 174 >UniRef50_A7SNK1 Cluster: Predicted protein; n=2; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 526 Score = 56.8 bits (131), Expect = 6e-07 Identities = 34/108 (31%), Positives = 55/108 (50%), Gaps = 6/108 (5%) Frame = +2 Query: 269 LQMNWIDKRLSWSAGEWGCSTWL-VSSERLWRPDVVLLNAA-----ATTAGDYALRARVS 430 ++MNW + L W+A E+G L +S +W PD+VL N A A T + + ++ Sbjct: 136 VRMNWNNHLLRWNASEYGGIDKLNISPTLMWLPDIVLHNNAEENVPAGTLYQFKTKVQLF 195 Query: 431 NNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFV 574 N+G W I + ++ + +P D Q C KFGS +N E++ V Sbjct: 196 NDGLCVWYAPTIIQSGCNIDITYFPFDDQLCELKFGSWTYNGLEVNIV 243 >UniRef50_A7RUG1 Cluster: Predicted protein; n=2; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 497 Score = 56.8 bits (131), Expect = 6e-07 Identities = 41/176 (23%), Positives = 83/176 (47%), Gaps = 14/176 (7%) Frame = +2 Query: 137 MIDSLLATYDRESPP-----DSKIVVNLTLHL-RHANIRESESTVRILADLQMNWIDKRL 298 ++ LL Y++++ P ++ +V L L + N+ + + ++ W + L Sbjct: 15 LLGDLLKGYNKDAHPVPILNKTQYMVTFGLELVQLVNVDDKNQIITTNVWVRQRWTNLLL 74 Query: 299 SWSAGEWGCSTWL-VSSERLWRPDVVLLNAAAT--TAG--DYALRARVSNNGSVSWIKRL 463 W ++G T + + + ++W PD+VL N+A + + G Y R ++++G +W Sbjct: 75 KWDPDKYGGITRVRIDASKIWIPDIVLYNSADSEFSGGLEKYKTRVILNHDGVNAWYSPA 134 Query: 464 DISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDKR-IYS--MFESXAWDV 622 + + + +P D QTC KFGS ++D DK ++S +S WD+ Sbjct: 135 SFRSTCQIDVTFFPFDQQTCFMKFGSWTFEVVDLDIFADKSPLHSSQYMKSAEWDL 190 >UniRef50_P91197 Cluster: Acetylcholine receptor protein 11; n=2; Caenorhabditis|Rep: Acetylcholine receptor protein 11 - Caenorhabditis elegans Length = 461 Score = 56.4 bits (130), Expect = 8e-07 Identities = 42/166 (25%), Positives = 72/166 (43%), Gaps = 9/166 (5%) Frame = +2 Query: 110 CENATSLSLMIDSLLATYDRESPP----DSKIVVNLTLHLRHA-NIRESESTVRILADLQ 274 C+ + + + + LL Y+ P + V + L L+ ++ E V + A L Sbjct: 20 CDGSVAETKLFTDLLKGYNPLERPVQNSSQPLEVKIKLFLQQILDVDEKNQIVSVNAWLS 79 Query: 275 MNWIDKRLSWSAGEWGCSTWLV---SSERLWRPDVVLLNAAATT-AGDYALRARVSNNGS 442 W D +L W ++G + SS+ +W+PDV+L N+AA + + G+ Sbjct: 80 YTWFDHKLQWEPKKYGGIQDIRFPGSSDHIWKPDVLLYNSAAEDFDSTFKSNLLTYHTGT 139 Query: 443 VSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVID 580 V WI + + + +P D Q C KFGS + +D ID Sbjct: 140 VVWIPPGVLKFVCQLDVTWFPFDDQVCEMKFGSWTFHGYAIDLQID 185 >UniRef50_O62083 Cluster: Putative uncharacterized protein acr-19; n=2; Caenorhabditis|Rep: Putative uncharacterized protein acr-19 - Caenorhabditis elegans Length = 554 Score = 56.4 bits (130), Expect = 8e-07 Identities = 31/104 (29%), Positives = 52/104 (50%), Gaps = 2/104 (1%) Frame = +2 Query: 269 LQMNWIDKRLSWSAGEWG-CSTWLVSSERLWRPDVVLLNAAATTAGD-YALRARVSNNGS 442 L+M+W D L+W E+G + +W+PDV+L N+ + + A V G+ Sbjct: 77 LRMSWTDHYLTWDPSEFGNIKEVRLPINNIWKPDVLLYNSVDQQFDSTWPVNAVVLYTGN 136 Query: 443 VSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFV 574 V+WI I + ++ + +P D Q CT KFGS ++ D + Sbjct: 137 VTWIPPAIIRSSCAIDIAYFPFDTQHCTMKFGSWTYSGFFTDLI 180 >UniRef50_A5H038 Cluster: Nicotinic acetylcholine receptor subunit 6 isoform VIII; n=1; Musca domestica|Rep: Nicotinic acetylcholine receptor subunit 6 isoform VIII - Musca domestica (House fly) Length = 396 Score = 56.4 bits (130), Expect = 8e-07 Identities = 39/154 (25%), Positives = 73/154 (47%), Gaps = 7/154 (4%) Frame = +2 Query: 137 MIDSLLATYDRESPP----DSKIVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLS 301 +++ LL+TY+ P + V L L+ ++ E + L + W D L Sbjct: 29 LLNHLLSTYNTLERPVANESDPLEVKFGLTLQQIIDVDEKNQLLITNLWLSLEWNDYNLR 88 Query: 302 WSAGEWGCSTWL-VSSERLWRPDVVLLNAAATTA-GDYALRARVSNNGSVSWIKRLDIST 475 W+ E+G L ++ +LW+PDV++ N+A G Y V +NG+ ++ + Sbjct: 89 WNDSEYGGVKDLRITPNKLWKPDVLMYNSADEGFDGTYHTNIVVKHNGNCLYVPPGIFKS 148 Query: 476 PISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVI 577 + + +P D Q C KFGS ++ +++D V+ Sbjct: 149 TCKIDITWFPFDDQHCEMKFGSWTYDGNQLDLVL 182 >UniRef50_Q7KT97 Cluster: CG32975-PB, isoform B; n=69; Eumetazoa|Rep: CG32975-PB, isoform B - Drosophila melanogaster (Fruit fly) Length = 808 Score = 56.0 bits (129), Expect = 1e-06 Identities = 30/102 (29%), Positives = 51/102 (50%), Gaps = 2/102 (1%) Frame = +2 Query: 269 LQMNWIDKRLSWSAGEWGCSTWL-VSSERLWRPDVVLLNAAATTA-GDYALRARVSNNGS 442 L++ W D L W+ ++G L + R+W+PDV++ N+A G Y V NNGS Sbjct: 365 LKLEWNDMNLRWNTSDYGGVKDLRIPPHRIWKPDVLMYNSADEGFDGTYQTNVVVRNNGS 424 Query: 443 VSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 568 ++ + + + +P D Q C KFGS ++ ++D Sbjct: 425 CLYVPPGIFKSTCKIDITWFPFDDQRCEMKFGSWTYDGFQLD 466 >UniRef50_Q17BK9 Cluster: Nicotinic acetylcholine receptor, putative; n=1; Aedes aegypti|Rep: Nicotinic acetylcholine receptor, putative - Aedes aegypti (Yellowfever mosquito) Length = 378 Score = 56.0 bits (129), Expect = 1e-06 Identities = 35/128 (27%), Positives = 60/128 (46%), Gaps = 4/128 (3%) Frame = +2 Query: 209 LHLRHANIRESESTVRILADLQMNWIDKRLSWSAGEW-GCSTWLVSSERLWRPDVVLLNA 385 L L++ +I + + I ++++W D+ L+W E G +V S+ +W PD++ A Sbjct: 3 LVLQNFDIDDDRQKLFINVWIRLSWKDQFLTWDPREHNGLKDLMVDSKDIWLPDMMPYAA 62 Query: 386 AATTAGDYAL---RARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNS 556 + D + + V ++G V I D + NWP D CT +FG S Sbjct: 63 YYSNNLDVSCTSPKCSVLSDGEVRCIPACDYHSLCETDFRNWPFDRMNCTIRFGMWAEYS 122 Query: 557 DEMDFVID 580 +E+DF D Sbjct: 123 NEVDFTAD 130 >UniRef50_A7S9T6 Cluster: Predicted protein; n=2; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 321 Score = 56.0 bits (129), Expect = 1e-06 Identities = 34/155 (21%), Positives = 76/155 (49%), Gaps = 10/155 (6%) Frame = +2 Query: 134 LMIDSLLATYDRESPPDSKI--VVNLTLHLRHANIRESESTVRILAD---LQMNWIDKRL 298 L+ L A Y P ++ VV ++ + ++ + +IL +++ W D L Sbjct: 6 LLYKHLFANYSNVVRPVKRVEEVVPVSFDIGYSQMVNLVEKNQILISNLWVRLKWYDPWL 65 Query: 299 SWSAGEWG-CSTWLVSSERLWRPDVVLLNAA-ATTAGD---YALRARVSNNGSVSWIKRL 463 +W+ ++G + V +W PD+VL N + ++G+ + + + ++G+V W+ + Sbjct: 66 TWNESDFGGMKSIKVDPSCVWVPDIVLYNNVDSDSSGEMYKFTTKVNIHSDGTVQWLSPI 125 Query: 464 DISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 568 + + + + N+P D Q C +FGS ++ E++ Sbjct: 126 QVKSECKIDITNFPLDEQFCKLEFGSWAYDGFELN 160 >UniRef50_A6QL44 Cluster: Nicotinic acetylcholine receptor non-alpha subunit precursor ShAR2beta; n=1; Schistosoma haematobium|Rep: Nicotinic acetylcholine receptor non-alpha subunit precursor ShAR2beta - Schistosoma haematobium (Blood fluke) Length = 545 Score = 56.0 bits (129), Expect = 1e-06 Identities = 32/130 (24%), Positives = 64/130 (49%), Gaps = 3/130 (2%) Frame = +2 Query: 188 KIVVNLTLHL-RHANIRESESTVRILADLQMNWIDKRLSWSAGEWGCSTWL-VSSERLWR 361 K+VV L + + + E++ +R W D L W+A ++G L + ++W Sbjct: 60 KMVVQYGLQMIQLLGLDENKQVLRTNCWAVYRWSDSLLKWNASQYGGIKELRIFPHQIWT 119 Query: 362 PDVVLLNAAATTAGDYAL-RARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFG 538 PD+ L N A ++ R V ++G++ WI++ + +++ +P D Q C +FG Sbjct: 120 PDIKLYNFADERLQEFREGRLVVDSSGNILWIQQALFRSTCQVEITYFPFDSQVCMLEFG 179 Query: 539 SRMHNSDEMD 568 S ++ ++D Sbjct: 180 SMAYDKTQLD 189 >UniRef50_Q10052 Cluster: Gaba/glycine receptor family (See gbr) protein 3; n=4; Caenorhabditis|Rep: Gaba/glycine receptor family (See gbr) protein 3 - Caenorhabditis elegans Length = 438 Score = 55.6 bits (128), Expect = 1e-06 Identities = 49/171 (28%), Positives = 80/171 (46%), Gaps = 10/171 (5%) Frame = +2 Query: 83 TCAIASAAECE-NATSLSLMIDSLLATYDRESPPDSKIVVNLTLHLRHANIRE-SESTVR 256 T ++ A CE N+ ++ LL YD+ P + V +++ L +I SE + Sbjct: 20 TESLVDPAHCEYNSNHRKSILTDLLQDYDKTMVPSNNSV-QVSVELTVQDISSISEISSS 78 Query: 257 ILADLQMN--WIDKRLSWSAGEWGCSTWLVS--SERLWRPDVVLLNAAATTAGDYA---L 415 +AD+ + W D RL + + L S SERLW P+V +N+ +T + Sbjct: 79 FIADVWFSQVWYDPRLEYRNISCKTNLSLDSYVSERLWTPNVCFVNSKSTQVHKSPASNI 138 Query: 416 RARVSNNGSVSWIK-RLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEM 565 + NG+V W+ R+ +S P S +L +P D Q C F S +N E+ Sbjct: 139 LLIIYPNGTV-WLNYRVQVSAPCSFELSRFPIDAQECHLVFESYSYNIAEV 188 >UniRef50_O17848 Cluster: Putative uncharacterized protein acr-18; n=2; Caenorhabditis|Rep: Putative uncharacterized protein acr-18 - Caenorhabditis elegans Length = 510 Score = 55.6 bits (128), Expect = 1e-06 Identities = 34/139 (24%), Positives = 62/139 (44%), Gaps = 6/139 (4%) Frame = +2 Query: 230 IRESESTVRILADLQMNWIDKRLSWSAGEWG-CSTWLVSSERLWRPDVVLLNAAATTA-- 400 + E + V I L++ WID+ L+W ++G S V + ++W+PDV++ N A Sbjct: 69 VDERDQIVNIYCWLELYWIDETLTWDPKKFGNLSRIHVPAHKIWKPDVLVYNNANMNVEE 128 Query: 401 GDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVID 580 + A V N G V + + ++ L +P D Q C F S + ++D Sbjct: 129 NEMETNAIVDNTGRVMLFRSMITDISCNLNLQQFPFDQQICFVTFASWSMDGSKLDLSAT 188 Query: 581 KRIYSM---FESXAWDVTD 628 + ++ + W +TD Sbjct: 189 PKTDNLELYIRNTEWGLTD 207 >UniRef50_A7RNI2 Cluster: Predicted protein; n=3; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 485 Score = 55.6 bits (128), Expect = 1e-06 Identities = 40/175 (22%), Positives = 80/175 (45%), Gaps = 13/175 (7%) Frame = +2 Query: 137 MIDSLLATYDRESPP--DSKIVVNLTLHLRHANIRESESTVRILAD---LQMNWIDKRLS 301 +++ L Y++E+ P + + + + +A + S +IL + W++ L+ Sbjct: 30 LLNDLFKDYNKEARPVLNKSEAIEVQFDMAYAQLINLNSKDQILQSKVWFRQRWVNPFLT 89 Query: 302 WSAGEWGCSTWL-VSSERLWRPDVVLLN--AAATTAGDYAL--RARVSNNGSVSWIKRLD 466 W +G T + V+ +W+PD+VL + T Y RA + +NG W + Sbjct: 90 WDPKMYGGLTSINVNPNMIWKPDIVLYHNIGFGETGAIYKFDTRATIMHNGYTEWFAPTE 149 Query: 467 ISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVI--DKRIYSMF-ESXAWDV 622 I + ++ + +P D Q C KFGS ++ +++ D S + +S WD+ Sbjct: 150 IHSICAIDITYFPFDEQFCKMKFGSWSYSGRQLNLTSKGDSADLSKYTKSGEWDL 204 >UniRef50_O61519 Cluster: Ligand-gated ion channel protein 6; n=4; Caenorhabditis elegans|Rep: Ligand-gated ion channel protein 6 - Caenorhabditis elegans Length = 462 Score = 55.2 bits (127), Expect = 2e-06 Identities = 37/156 (23%), Positives = 73/156 (46%), Gaps = 6/156 (3%) Frame = +2 Query: 92 IASAAECENATSLSLMIDSLLATYDRE-SPPDSKIVVNLTLH-LRHANIRESESTVRILA 265 + + A E + + +L+ TYD + P D +V +T + ++ +++ T++ Sbjct: 17 LTAVAFLETSNTETLLQQLFNQTYDVDMKPSDDLTMVTITPNTFILLSMDQTQETIQYSE 76 Query: 266 DLQMNWIDKRLSWSAGEWGCST-WL-VSSERLWRPDVVLLNAA-ATTAGDYALR-ARVSN 433 + + W D L W+ W+ +S+ R W PDV+ N D ++ A + Sbjct: 77 EFLLRWYDPILHWNQSAVSYENDWIKISASRAWIPDVIFTNGIDMDPLLDKDMQMADLRY 136 Query: 434 NGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 541 NG + + +S+P +++DN+P D+Q C GS Sbjct: 137 NGEIRTSRPAVVSSPCPLEIDNFPYDVQKCNISMGS 172 >UniRef50_A7RS33 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 460 Score = 55.2 bits (127), Expect = 2e-06 Identities = 42/172 (24%), Positives = 76/172 (44%), Gaps = 11/172 (6%) Frame = +2 Query: 149 LLATYDRESPP----DSKIVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWSAG 313 LLA Y R P D I + + L ++ E T+ + +++ W D RL W+ Sbjct: 9 LLANYSRNIIPQKYKDIPIKIKFDIALNQIIDLDERLQTITTIVWVRLYWTDFRLRWNHT 68 Query: 314 EWG-CSTWLVSSERLWRPDVVLLNAAATT---AGDYALRARVSNNGSVSWIKRLDISTPI 481 ++G +++ S +LW PD+ L N A + V+++GS+ W + Sbjct: 69 KYGGIKSFVTPSRQLWLPDITLYNNANDNYEKEKEEYYGLTVNSDGSIGWYYPTIFKSSC 128 Query: 482 SMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVID--KRIYSMFESXAWDVTDL 631 ++ + +P D Q C KFGS ++ +D I S ++ W + D+ Sbjct: 129 TIDVTYFPFDDQKCILKFGSWSYHGLSLDIFHSGPGDIKSFTDNGEWVLVDM 180 >UniRef50_Q4RZC6 Cluster: Chromosome 1 SCAF14944, whole genome shotgun sequence; n=1; Tetraodon nigroviridis|Rep: Chromosome 1 SCAF14944, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 547 Score = 54.8 bits (126), Expect = 2e-06 Identities = 27/105 (25%), Positives = 50/105 (47%), Gaps = 2/105 (1%) Frame = +2 Query: 269 LQMNWIDKRLSWSAGEW-GCSTWLVSSERLWRPDVVLLNAAATT-AGDYALRARVSNNGS 442 ++ W D L W+ ++ G + S +WRPD+VL N A +G ++ NG Sbjct: 139 IRQRWNDAYLKWNKEDYDGLEVIHIPSSLVWRPDLVLYNKADDDFSGPMDTNVKLRYNGE 198 Query: 443 VSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVI 577 ++W + + + +P D Q C FGS +N +++D ++ Sbjct: 199 ITWDAPAITKSSCVVDVSYFPFDSQECNLTFGSWTYNGNQVDIIM 243 >UniRef50_UPI0000E4930A Cluster: PREDICTED: similar to nicotinic acetylcholine receptor subunit Dalpha7; n=1; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to nicotinic acetylcholine receptor subunit Dalpha7 - Strongylocentrotus purpuratus Length = 1094 Score = 54.4 bits (125), Expect = 3e-06 Identities = 28/102 (27%), Positives = 50/102 (49%), Gaps = 2/102 (1%) Frame = +2 Query: 269 LQMNWIDKRLSWSAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGD-YALRARVSNNGS 442 ++ W D L+W+ E+G + V + +WRPD+++ N+AA + + V++ G Sbjct: 757 MRQRWTDPTLAWNKSEYGGLDKIRVLPDMIWRPDILVYNSAAPKFDPTFHTKVTVTSEGL 816 Query: 443 VSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 568 WI T + + +P D+Q C KFGS + +D Sbjct: 817 CEWIPPGIFKTSCPIDVTYFPFDIQECEIKFGSWTYGGFTVD 858 >UniRef50_UPI0000E47621 Cluster: PREDICTED: similar to nicotinic acetylcholine receptor subunit type G, partial; n=1; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to nicotinic acetylcholine receptor subunit type G, partial - Strongylocentrotus purpuratus Length = 283 Score = 54.4 bits (125), Expect = 3e-06 Identities = 40/159 (25%), Positives = 69/159 (43%), Gaps = 5/159 (3%) Frame = +2 Query: 113 ENATSLSLMIDSLLATYDRESP-PDSKIVVNLTLHLRHA-NIRESESTVRILADLQMNWI 286 E A +S ++D +T R + I V + L + + ++ E+ + + W Sbjct: 11 EEALLVSRLLDHGYSTIVRPVMYQEDTITVKIDLAIVNLLDMDEANQIMTANTFMTQEWN 70 Query: 287 DKRLSWSAGE-WGCSTWLVSSERLWRPDVVLLNAA--ATTAGDYALRARVSNNGSVSWIK 457 D L W E W + V +WRPD++L N A G A + +G+V+W Sbjct: 71 DAFLQWEPSESWNITDVQVPINNIWRPDIILHNNANDELNGGIRWTHAWIRYDGTVTWKT 130 Query: 458 RLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFV 574 + + M +P D Q C+ K GS +N DE++ + Sbjct: 131 NYILMSACPMNPLYFPFDTQNCSLKLGSWTYNEDEINVI 169 >UniRef50_Q9XTY8 Cluster: Putative uncharacterized protein lgc-25; n=3; Caenorhabditis|Rep: Putative uncharacterized protein lgc-25 - Caenorhabditis elegans Length = 502 Score = 54.4 bits (125), Expect = 3e-06 Identities = 31/128 (24%), Positives = 55/128 (42%), Gaps = 4/128 (3%) Frame = +2 Query: 197 VNLTLHLRHAN-IRESESTVRILADLQMNWIDKRLSWSAGEWGCSTWLVSSERLWRPDVV 373 VN+ L + H + E E T + + WID+ + W A + + +S+ LW+P + Sbjct: 54 VNVFLSIAHVEKVDEHEQTALVHGHIWATWIDEYMQWDAKKENVTKLTISAHSLWQPALA 113 Query: 374 LLNAAATTAGDY---ALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSR 544 L N+A + A+ A V + G V NWP D Q+C Sbjct: 114 LYNSARGNSWHLYMGAMPATVYSTGKVWSTGTFSFYVTCQFDFTNWPFDQQSCPIVIADW 173 Query: 545 MHNSDEMD 568 ++N ++++ Sbjct: 174 VYNLNQVN 181 >UniRef50_Q9N5U8 Cluster: Acetylcholine receptor protein 21; n=2; Caenorhabditis|Rep: Acetylcholine receptor protein 21 - Caenorhabditis elegans Length = 469 Score = 54.4 bits (125), Expect = 3e-06 Identities = 35/151 (23%), Positives = 73/151 (48%), Gaps = 8/151 (5%) Frame = +2 Query: 149 LLATYDRESPPD--SKIVVNLTLHLRHANIRESESTVRILAD---LQMNWIDKRLSWSAG 313 LL Y+ E P SK +N+T I + + +IL ++++W+D +L W Sbjct: 7 LLYDYNNEVRPSVHSKEPINVTFVFSLTQIIDVDERNQILTTNSWIRLHWVDYKLVWDPR 66 Query: 314 EWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYALRARVSNN--GSVSWIKRLDISTPIS 484 + T + + S+++W+PD++L N A + V + G++ W ++ Sbjct: 67 LYQNVTRIHIPSDKIWKPDIILYNNADAQYMKSVMSTDVIVDYLGNIHWPLSAIFTSSCP 126 Query: 485 MQLDNWPNDMQTCTFKFGSRMHNSDEMDFVI 577 + + ++P D QTC K+ S ++ ++D ++ Sbjct: 127 LDVKHYPFDRQTCILKYASWAYDGTKIDLLL 157 >UniRef50_Q2XWL2 Cluster: Nicotinic acetylcholine receptor subunit type A; n=1; Lymnaea stagnalis|Rep: Nicotinic acetylcholine receptor subunit type A - Lymnaea stagnalis (Great pond snail) Length = 485 Score = 54.4 bits (125), Expect = 3e-06 Identities = 34/133 (25%), Positives = 60/133 (45%), Gaps = 3/133 (2%) Frame = +2 Query: 191 IVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWSAGEWGCSTWL-VSSERLWRP 364 I VN + L+ ++ E + L+M W L W E+G T + V + +W P Sbjct: 53 INVNFGIILQQIIDVDEKNQIIHTNIWLRMTWNAANLMWDPKEYGNLTSIRVPKQMVWVP 112 Query: 365 DVVLLNAAATTAGD-YALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 541 D++L N+A+ D Y ++ NG+ W+ + ++ + +P D Q C K+GS Sbjct: 113 DILLYNSASDGFDDTYPTNVVINYNGNCLWVPPGMFKSTCAIDITWFPFDDQRCNLKYGS 172 Query: 542 RMHNSDEMDFVID 580 H ++ D Sbjct: 173 WTHEGHLLNLTAD 185 >UniRef50_Q07001 Cluster: Acetylcholine receptor subunit delta precursor; n=38; Gnathostomata|Rep: Acetylcholine receptor subunit delta precursor - Homo sapiens (Human) Length = 517 Score = 54.4 bits (125), Expect = 3e-06 Identities = 37/142 (26%), Positives = 67/142 (47%), Gaps = 7/142 (4%) Frame = +2 Query: 161 YDRESPP----DSKIVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWSAGEWG- 322 Y++E P + + V L L L + +++E E T+ ++ W D RL W+A E+G Sbjct: 38 YNKELRPVAHKEESVDVALALTLSNLISLKEVEETLTTNVWIEHGWTDNRLKWNAEEFGN 97 Query: 323 CSTWLVSSERLWRPDVVL-LNAAATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDN 499 S + + +W P++VL N + Y+ V + G V W+ + + + Sbjct: 98 ISVLRLPPDMVWLPEIVLENNNDGSFQISYSCNVLVYHYGFVYWLPPAIFRSSCPISVTY 157 Query: 500 WPNDMQTCTFKFGSRMHNSDEM 565 +P D Q C+ KF S + + E+ Sbjct: 158 FPFDWQNCSLKFSSLKYTAKEI 179 >UniRef50_UPI0000ECB6ED Cluster: Acetylcholine receptor subunit alpha precursor.; n=1; Gallus gallus|Rep: Acetylcholine receptor subunit alpha precursor. - Gallus gallus Length = 352 Score = 54.0 bits (124), Expect = 4e-06 Identities = 37/145 (25%), Positives = 66/145 (45%), Gaps = 10/145 (6%) Frame = +2 Query: 137 MIDSLLATYDRESPPDSK----IVVNLTLHL-RHANIRESESTVRILADLQMNWIDKRLS 301 ++D L Y + P +VV + L L + N+ E V L+ W D L Sbjct: 26 LVDDLFRDYSKVVRPVENHRDAVVVTVGLQLIQLINVDEVNQIVTTNVRLKQQWTDINLK 85 Query: 302 WSAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNGSVSWIKRLD 466 W+ ++G + + S+ +WRPD+VL N A GD+A+ + + + G ++W Sbjct: 86 WNPDDYGGVKQIRIPSDDIWRPDLVLYNNA---DGDFAIVKYTKVLLEHTGKITWTPPAI 142 Query: 467 ISTPISMQLDNWPNDMQTCTFKFGS 541 + + + +P D Q C+ K G+ Sbjct: 143 FKSYCEIIVTYFPFDQQNCSMKLGT 167 >UniRef50_Q67X94 Cluster: Putative uncharacterized protein lgc-2; n=3; Caenorhabditis|Rep: Putative uncharacterized protein lgc-2 - Caenorhabditis elegans Length = 509 Score = 54.0 bits (124), Expect = 4e-06 Identities = 35/153 (22%), Positives = 73/153 (47%), Gaps = 10/153 (6%) Frame = +2 Query: 137 MIDSLLATYDRESPPDSKIVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWSAG 313 + + LL+ ++ +PPD + V L L H I E + T+ +L + +W+D L+W Sbjct: 70 LTEYLLSRHNLNAPPDGLLYVEYELELVHILGIDELKQTMTVLIYVDEHWVDPSLTWDPA 129 Query: 314 EWG--CSTWLVSSERLWRPDVVLLNAAATTAGDY-----ALR--ARVSNNGSVSWIKRLD 466 +G TW + +++W PD+++ N + + A+R AR+ NG++ Sbjct: 130 LFGGITKTW-IPLDKIWVPDIIVFNMVKSNRLAHEDLLSAVRAPARIHYNGTIVASHPAV 188 Query: 467 ISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEM 565 + + + ++P D Q C + S + +++ Sbjct: 189 HTVSCEINIRHFPLDDQRCAIEIASWAYGQEKI 221 >UniRef50_A7RS32 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 325 Score = 54.0 bits (124), Expect = 4e-06 Identities = 40/152 (26%), Positives = 70/152 (46%), Gaps = 12/152 (7%) Frame = +2 Query: 149 LLATYDRESPP----DSKIVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWSAG 313 L TY+++ P D + V L L L ++ + T+ ++ ++ W D RL W+ Sbjct: 20 LFRTYNKDVLPKETLDKGVPVRLDLALNQIIDVNKRAQTMTVVIWVRQYWRDPRLRWNVS 79 Query: 314 EW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYAL------RARVSNNGSVSWIKRLDIS 472 + G ++ + RLW PD+ L N A DY L +++ G VS Sbjct: 80 AYDGVDNIVIKASRLWLPDITLYNNA---RDDYKLDKESQHSLTITSRGGVSRFFPTIYK 136 Query: 473 TPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 568 + ++ + ++P D QTC K GS +N E++ Sbjct: 137 SSCALNIRHFPFDDQTCILKLGSWSYNVFEVN 168 >UniRef50_P18505 Cluster: Gamma-aminobutyric acid receptor subunit beta-1 precursor (GABA(A) receptor subunit beta-1); n=104; Euteleostomi|Rep: Gamma-aminobutyric acid receptor subunit beta-1 precursor (GABA(A) receptor subunit beta-1) - Homo sapiens (Human) Length = 474 Score = 54.0 bits (124), Expect = 4e-06 Identities = 41/169 (24%), Positives = 73/169 (43%), Gaps = 7/169 (4%) Frame = +2 Query: 86 CAIASAAECENATSLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESESTV 253 C S E N + + +D LL YD PD + V + + + + + E Sbjct: 23 CCAHSTNEPSNMSYVKETVDRLLKGYDIRLRPDFGGPPVDVGMRIDVASIDMVSEVNMDY 82 Query: 254 RILADLQMNWIDKRLSWSAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---AR 424 + Q +W DKRLS+S + +++LW PD LN + ++ R Sbjct: 83 TLTMYFQQSWKDKRLSYSGIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIR 142 Query: 425 VSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDF 571 + +G+V + R+ + M L +P D Q CT + S + +D+++F Sbjct: 143 LHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEF 191 >UniRef50_P31644 Cluster: Gamma-aminobutyric acid receptor subunit alpha-5 precursor (GABA(A) receptor subunit alpha-5); n=86; Euteleostomi|Rep: Gamma-aminobutyric acid receptor subunit alpha-5 precursor (GABA(A) receptor subunit alpha-5) - Homo sapiens (Human) Length = 462 Score = 54.0 bits (124), Expect = 4e-06 Identities = 39/161 (24%), Positives = 73/161 (45%), Gaps = 7/161 (4%) Frame = +2 Query: 113 ENATSLSLMIDSLLATYDRESPPD--SKIV-VNLTLHLRHAN-IRESESTVRILADLQMN 280 +N T + ++D LL YD P +I V +++ + ++E I + + Sbjct: 44 DNITIFTRILDGLLDGYDNRLRPGLGERITQVRTDIYVTSFGPVSDTEMEYTIDVFFRQS 103 Query: 281 WIDKRLSWSAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSW 451 W D+RL + + + ++W PD N + A + R+ ++G++ + Sbjct: 104 WKDERLRFKGPMQRLPLNNLLASKIWTPDTFFHNGKKSIAHNMTTPNKLLRLEDDGTLLY 163 Query: 452 IKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFV 574 RL IS MQL+++P D C KFGS + + E+ +V Sbjct: 164 TMRLTISAECPMQLEDFPMDAHACPLKFGSYAYPNSEVVYV 204 >UniRef50_UPI0000D56893 Cluster: PREDICTED: similar to CG6698-PA; n=1; Tribolium castaneum|Rep: PREDICTED: similar to CG6698-PA - Tribolium castaneum Length = 419 Score = 53.6 bits (123), Expect = 6e-06 Identities = 32/118 (27%), Positives = 54/118 (45%), Gaps = 4/118 (3%) Frame = +2 Query: 197 VNLTLHLRHANIRESESTVRILADLQMNWIDKRLSWSAGEWG-CSTWLVSSERLWRPDVV 373 V L L + E +S ++ + + W D++L W+ E+G +T + +W P++ Sbjct: 224 VGLKLGTNIVTLNEYKSVLQYSGTISLTWHDEKLHWNTSEYGDINTLHIFRREIWIPELF 283 Query: 374 LLNAAATTAGDYA--LRARVSNNGSVSWIKRLDISTPISM-QLDNWPNDMQTCTFKFG 538 L NA A G+ V++ G V WI ++I++ S L WP D C G Sbjct: 284 LFNAIAEN-GELLEDTMLTVNSTGHVKWITTININSWCSPDDLGRWPRDEHQCDIVLG 340 >UniRef50_UPI000058896A Cluster: PREDICTED: similar to cholinergic receptor neuronal nicotinic alpha protein 2; n=5; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to cholinergic receptor neuronal nicotinic alpha protein 2 - Strongylocentrotus purpuratus Length = 329 Score = 53.6 bits (123), Expect = 6e-06 Identities = 34/108 (31%), Positives = 58/108 (53%), Gaps = 3/108 (2%) Frame = +2 Query: 227 NIRESESTVRILADLQMNWIDKRLSWSAGEWG-CSTWLVSSERLWRPDVVLLNA--AATT 397 NIR S S +R +M+W+D R+ W+ E+G S + V S ++ PD+ L N+ + T Sbjct: 39 NIRMSLSNLR-----EMHWVDPRMVWNPLEYGNISKFRVHSSEVFVPDITLYNSHSPSKT 93 Query: 398 AGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 541 D + ++N+G+V + + I S+ L ++P D C K+GS Sbjct: 94 MSD-DISTLMTNHGTVYYTPPVAIEAACSLDLKDYPYDSHICRLKWGS 140 >UniRef50_Q7PJX0 Cluster: ENSANGP00000022703; n=1; Anopheles gambiae str. PEST|Rep: ENSANGP00000022703 - Anopheles gambiae str. PEST Length = 223 Score = 53.6 bits (123), Expect = 6e-06 Identities = 37/160 (23%), Positives = 75/160 (46%), Gaps = 9/160 (5%) Frame = +2 Query: 182 DSKIVVNLTL--HLRHANIRESESTVRILADLQMNWIDKRLSWSAGEW-GCSTWLVSSER 352 D VN+T+ ++ ES++ +++ +++ W D+ L W++ EW G + SE Sbjct: 64 DHTQTVNVTVAYYVLTYEFEESDNLLQLGVWMELQWTDEYLRWNSTEWSGIERLAIGSEE 123 Query: 353 LWRPDVVLLNAAATTA--GDYAL-RARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTC 523 +W PD ++ + A + V+ NG+V + ++ WP D+ C Sbjct: 124 IWMPDFRHFSSYYNPEDLNECANPKCSVAPNGTVVCLPVCGMNAKCDADYSRWPFDVHRC 183 Query: 524 TFKFGSRMHNSDEMD-FVIDKRI--YSMFESXAWDVTDLS 634 +G+ ++ DE+D ++D + F+S W+V L+ Sbjct: 184 NLWYGTWANSMDEVDVHILDVCLGRNPEFKSPKWNVISLA 223 >UniRef50_Q4R170 Cluster: Putative uncharacterized protein; n=1; Caenorhabditis elegans|Rep: Putative uncharacterized protein - Caenorhabditis elegans Length = 404 Score = 53.6 bits (123), Expect = 6e-06 Identities = 33/136 (24%), Positives = 60/136 (44%), Gaps = 3/136 (2%) Frame = +2 Query: 176 PPDSKIVVNLTLHLRHANIRESESTVRILADLQMNWIDKRLSWSAGEWGCSTWL-VSSER 352 PP +I + L++ ++ + E E L D + +W D RLSW ++G + V + Sbjct: 79 PPRFEITIQLSM-MKLVEVVEPEEKATFLFDYRADWYDTRLSWDPEDYGGINHIYVPRSK 137 Query: 353 LWRPDVVLLNAAATTAGD--YALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCT 526 +W P+ +++ + D Y A + +NGS+ S M + +P D TC+ Sbjct: 138 VWIPETTIVDCSEIKVFDNEYTRYAWLHSNGSIGMYIASVTSVVCQMDVYKFPMDTHTCS 197 Query: 527 FKFGSRMHNSDEMDFV 574 F + +E V Sbjct: 198 VNFLFMTYQLEEFTIV 213 >UniRef50_Q18556 Cluster: Putative uncharacterized protein acr-9; n=2; Caenorhabditis|Rep: Putative uncharacterized protein acr-9 - Caenorhabditis elegans Length = 534 Score = 53.6 bits (123), Expect = 6e-06 Identities = 33/135 (24%), Positives = 66/135 (48%), Gaps = 5/135 (3%) Frame = +2 Query: 191 IVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWSAGEWGCSTWL---VSSERLW 358 +VV++ ++L+ ++ E + ++A ++ W D +L W E+G + ++ +W Sbjct: 53 LVVSVKIYLQQILDVDEKNQVITLVAWIEYQWTDYKLKWDPSEYGGIKDIRIPGNANAIW 112 Query: 359 RPDVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKF 535 +PDV+L N+A Y + VS G V + + + + +P D Q C KF Sbjct: 113 KPDVLLYNSADENFDSTYPVNYVVSYTGDVLQVPPGILKLSCKIDITYFPFDDQICHLKF 172 Query: 536 GSRMHNSDEMDFVID 580 GS ++ + +D I+ Sbjct: 173 GSWTYSGNFIDLRIN 187 >UniRef50_O18228 Cluster: Putative uncharacterized protein lgc-7; n=4; Caenorhabditis|Rep: Putative uncharacterized protein lgc-7 - Caenorhabditis elegans Length = 439 Score = 53.6 bits (123), Expect = 6e-06 Identities = 39/169 (23%), Positives = 75/169 (44%), Gaps = 8/169 (4%) Frame = +2 Query: 107 ECENATSLSLMIDSLLATYDRESPPDSK----IVVNLTLHLRHA-NIRESESTVRILADL 271 E + T + D L+ YD P + +++N++++ + +E T+ ++ Sbjct: 21 EVDGITVAEQLKDVLMEGYDSSIRPVNNERDILIINISMNTMSVLTLDPAEETINFSSEF 80 Query: 272 QMNWIDKRLSWSAGEWGCSTWLVSSER-LWRPDVVLLNAAATT-AGDYALR-ARVSNNGS 442 + W D+ L W+ ++ TWL E LW PD + + T D + R V ++G+ Sbjct: 81 ILQWKDEFLFWNKSDYNI-TWLKLKESFLWTPDTTVSTSIDTNYLIDASERYVSVKHDGT 139 Query: 443 VSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDKRI 589 V + M +D +P D QTC K G + + E+ ++ + I Sbjct: 140 VRQSIYAVFTNLCDMNVDKFPYDQQTCMIKMGPWSYTTQEVTCIVGRDI 188 >UniRef50_UPI00006A0B5C Cluster: Gamma-aminobutyric-acid receptor subunit alpha-3 precursor (GABA(A) receptor subunit alpha-3).; n=2; Xenopus tropicalis|Rep: Gamma-aminobutyric-acid receptor subunit alpha-3 precursor (GABA(A) receptor subunit alpha-3). - Xenopus tropicalis Length = 465 Score = 53.2 bits (122), Expect = 7e-06 Identities = 29/122 (23%), Positives = 60/122 (49%), Gaps = 3/122 (2%) Frame = +2 Query: 215 LRHANIRESESTVRILADLQMNWIDKRLSWSAGEWGCSTWLVSSERLWRPDVVLLNAAAT 394 ++ N+ E T+ + + +W+D+RL + + + ++W PD N + Sbjct: 76 VKQVNMPSLEYTIDVF--FRQSWLDERLKFDGPIRTLPLNNLLASKIWTPDTFFHNGKKS 133 Query: 395 TAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEM 565 A + R+ +NG++ + RL I +M L+++P D+ C KFGS M+ ++++ Sbjct: 134 VAHNMTTPNKLLRLIDNGTLLYTMRLTIHAECTMHLEDFPMDVHACPLKFGSCMYCNEQV 193 Query: 566 DF 571 F Sbjct: 194 SF 195 >UniRef50_Q2XWK9 Cluster: Nicotinic acetylcholine receptor subunit type D; n=1; Lymnaea stagnalis|Rep: Nicotinic acetylcholine receptor subunit type D - Lymnaea stagnalis (Great pond snail) Length = 554 Score = 53.2 bits (122), Expect = 7e-06 Identities = 34/135 (25%), Positives = 63/135 (46%), Gaps = 2/135 (1%) Frame = +2 Query: 188 KIVVNLTLHLRHANIRESESTVRILADLQMNWIDKRLSWSAGEWGCSTWL-VSSERLWRP 364 K+++ +TL + ++ E + L W D++L W+ ++ L + LW+P Sbjct: 106 KVLIGITL-TQIFDLDEKNQVLTTNVWLDQEWTDQKLHWNPTDYNDLKRLRIPCRHLWKP 164 Query: 365 DVVLLNAAAT-TAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 541 D+VL N+ T G A V + G V W + + + + +P D Q C+ K GS Sbjct: 165 DIVLYNSVEDYTDGYMQSLAMVHHTGVVFWPPIVRFQSTCQVDITYFPFDDQVCSMKLGS 224 Query: 542 RMHNSDEMDFVIDKR 586 ++ ++D +D R Sbjct: 225 WAYDGFQVD--VDNR 237 >UniRef50_Q2XWK4 Cluster: Nicotinic acetylcholine receptor subunit type I; n=1; Lymnaea stagnalis|Rep: Nicotinic acetylcholine receptor subunit type I - Lymnaea stagnalis (Great pond snail) Length = 527 Score = 53.2 bits (122), Expect = 7e-06 Identities = 42/178 (23%), Positives = 78/178 (43%), Gaps = 14/178 (7%) Frame = +2 Query: 137 MIDSLLATYDRESPPDSKIVV---NLTLH-----LRHANIRESESTVRILADLQMNWIDK 292 +I SLL Y+R+ ++ N+T+ ++ ++ ES ++ + W D Sbjct: 62 LISSLLKKYERQGKQGRPVINTSDNMTVLFGLSLIQILDVDESNQVLKASMWYRYEWNDM 121 Query: 293 RLSWS-AGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYA-LRARVSNNGSVSWIKRLD 466 L W A + + S +W PD++L N A + V NNG + W+ + Sbjct: 122 LLKWDPAMHDDIQSIRIPSSMIWLPDILLYNFADDRLREQRDALCIVQNNGDIQWMPQAI 181 Query: 467 ISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEM--DFVIDKR--IYSMFESXAWDVTD 628 + + S +P D+Q+C KFGS +N ++ +FV + + S WD+ + Sbjct: 182 LRSSCSFDTKYFPFDVQSCWLKFGSWTYNGFKLNVEFVREHSFDLSDYVMSNEWDIIE 239 >UniRef50_Q21645 Cluster: Acetylcholine receptor protein 10; n=2; Caenorhabditis|Rep: Acetylcholine receptor protein 10 - Caenorhabditis elegans Length = 510 Score = 53.2 bits (122), Expect = 7e-06 Identities = 32/113 (28%), Positives = 52/113 (46%), Gaps = 4/113 (3%) Frame = +2 Query: 251 VRILADLQMNWIDKRLSWSAGEWGCST---WLVSSERLWRPDVVLLNAAATTA-GDYALR 418 + + A L+ W+D RL W ++ T + ++WRPD++L N+A+ + Sbjct: 12 IEVNAWLKYVWMDYRLQWDPLQYDNITSIRFAGGENQIWRPDILLYNSASEDFDSSFKSN 71 Query: 419 ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVI 577 V N G V+WI M + +P D Q C KFGS ++ +D I Sbjct: 72 EVVYNTGEVNWIPPGIFRASCKMDITYFPFDDQVCYLKFGSWTYHGLALDLSI 124 >UniRef50_A7S2J7 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 462 Score = 53.2 bits (122), Expect = 7e-06 Identities = 40/150 (26%), Positives = 71/150 (47%), Gaps = 10/150 (6%) Frame = +2 Query: 122 TSLSLMIDSLLATYDRESPP---DS-KIVVNLTLHLRHANIRESEST-VRILADLQMNWI 286 T+ ++ L YD E P DS K+ V +L L S+S V + ++ W Sbjct: 36 TAEKRLLADLFRNYDSEVRPVFNDSDKVNVEFSLSLIQIIAVNSKSQLVTVSVWIRQKWT 95 Query: 287 DKRLSWSAGEWG-CSTWLVSSERLWRPDVVLLNAAATT-AGD---YALRARVSNNGSVSW 451 + L+W+ ++G + ++ ++W PD++L N A T AG Y S++G+ W Sbjct: 96 NPMLAWNTSKYGGIESVNLNPAKVWIPDIILYNNADETYAGGLEKYKTSVIASSDGTQEW 155 Query: 452 IKRLDISTPISMQLDNWPNDMQTCTFKFGS 541 ++ ++ + +P D Q C+ KFGS Sbjct: 156 NSPASFTSTCNINVRYFPFDSQNCSLKFGS 185 >UniRef50_UPI0000F2C37E Cluster: PREDICTED: similar to CHRNG protein; n=1; Monodelphis domestica|Rep: PREDICTED: similar to CHRNG protein - Monodelphis domestica Length = 497 Score = 52.8 bits (121), Expect = 1e-05 Identities = 41/145 (28%), Positives = 67/145 (46%), Gaps = 10/145 (6%) Frame = +2 Query: 137 MIDSLLATYD---RESPPDSKIVVNLTLHLRHANI---RESESTVRILADLQMNWIDKRL 298 +++ L+ Y+ R + DS I+ N+TL L N+ E E + ++M W D RL Sbjct: 27 LLNDLMRNYNPNLRPAEVDSDII-NVTLKLTLTNLISLNEREEALTTNVWIEMQWCDYRL 85 Query: 299 SWSAGEWGCSTWL--VSSERLWRPDVVLLNAAATTAGDYALRARV--SNNGSVSWIKRLD 466 W ++ W+ + S +WRPD+VL N + AL V S NG + W+ Sbjct: 86 RWDPRDYE-DVWVLRIPSTMVWRPDIVLENNVDGVF-EVALYCNVLVSPNGCIYWLPPAI 143 Query: 467 ISTPISMQLDNWPNDMQTCTFKFGS 541 + + + +P D Q C+ F S Sbjct: 144 FRSSCPVTVTYFPFDWQNCSLVFQS 168 >UniRef50_UPI00015A4976 Cluster: 5-hydroxytryptamine receptor 3 subunit C; n=2; Danio rerio|Rep: 5-hydroxytryptamine receptor 3 subunit C - Danio rerio Length = 410 Score = 52.8 bits (121), Expect = 1e-05 Identities = 30/140 (21%), Positives = 59/140 (42%) Frame = +2 Query: 185 SKIVVNLTLHLRHANIRESESTVRILADLQMNWIDKRLSWSAGEWGCSTWLVSSERLWRP 364 + + V+LTL+ + E + ++ W + L+W E G + E++W P Sbjct: 10 TNVTVDLTLY-GILGVNEKSQVLETYLWVRTRWQIEGLTWDPAECGTKKISLPREKIWFP 68 Query: 365 DVVLLNAAATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSR 544 D+V+ V++ G V + I + + + +P D Q CT+ F S Sbjct: 69 DIVINEFMDENRAPDTYYVYVTSTGQVIDGRPFHIISSCKLDIYTFPFDFQNCTYTFNSY 128 Query: 545 MHNSDEMDFVIDKRIYSMFE 604 H+ D++ K + +F+ Sbjct: 129 KHSRDDVQLFFYKPVKDIFK 148 >UniRef50_Q6TMY0 Cluster: Nicotinic acetylcholine receptor non-alpha subunit precursor; n=3; Schistosoma|Rep: Nicotinic acetylcholine receptor non-alpha subunit precursor - Schistosoma bovis (Blood fluke) Length = 740 Score = 52.8 bits (121), Expect = 1e-05 Identities = 25/116 (21%), Positives = 56/116 (48%), Gaps = 2/116 (1%) Frame = +2 Query: 227 NIRESESTVRILADLQMNWIDKRLSWSAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAG 403 ++ E + + L + W D W+A ++ + + ER+W+PD++L N+A+ Sbjct: 74 DVDEKNQVLSTIIWLDLKWSDYHFHWNASDYENIRQINLPPERIWKPDILLYNSASEKFD 133 Query: 404 D-YALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 568 + + V N G++ W+ + ++++ +P D Q C K G+ + + +D Sbjct: 134 QIFPTKVIVRNTGNIQWVPPGLFHSICDIEVNWFPFDSQNCIMKLGTWTYQGNTVD 189 >UniRef50_Q0GQQ6 Cluster: Cys-loop ligand-gated ion channel subunit; n=3; Endopterygota|Rep: Cys-loop ligand-gated ion channel subunit - Apis mellifera (Honeybee) Length = 510 Score = 52.8 bits (121), Expect = 1e-05 Identities = 36/147 (24%), Positives = 65/147 (44%), Gaps = 8/147 (5%) Frame = +2 Query: 125 SLSLMIDSLLATYDRESPPD----SKIVVNLTLHLRHAN-IRESESTVRILADLQMNWID 289 ++++++++LL Y+ P + VV + +R + E + + + +W D Sbjct: 36 NITMVLENLLMNYENNQLPTHGKGTPTVVKTNILIRSMGPVSELDMDYSMDCYFRQSWRD 95 Query: 290 KRLSWSAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKR 460 RLS+ S + ER+WRPD N + + R+S +G + + R Sbjct: 96 SRLSFLGPIKSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRISQDGDILYSMR 155 Query: 461 LDISTPISMQLDNWPNDMQTCTFKFGS 541 L I M+L N+P D Q+C GS Sbjct: 156 LTIKAKCPMELRNFPMDRQSCPLILGS 182 >UniRef50_Q4V4V5 Cluster: IP12579p; n=6; Endopterygota|Rep: IP12579p - Drosophila melanogaster (Fruit fly) Length = 612 Score = 52.4 bits (120), Expect = 1e-05 Identities = 36/147 (24%), Positives = 64/147 (43%), Gaps = 8/147 (5%) Frame = +2 Query: 125 SLSLMIDSLLATYDRESPPDS----KIVVNLTLHLRHAN-IRESESTVRILADLQMNWID 289 ++S+++++LL Y++ P VV + +R + E + + + W D Sbjct: 107 NISMILENLLKRYEQSQLPTHGQGVPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRD 166 Query: 290 KRLSWSAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKR 460 KRLS+ S + +++WRPD N + + R+ NG + + R Sbjct: 167 KRLSFKGPIKSLSLSIKMLDKIWRPDTYFYNGKHSQIHMITVPNKLLRLDQNGGILYSMR 226 Query: 461 LDISTPISMQLDNWPNDMQTCTFKFGS 541 L I M+L N+P D Q+C GS Sbjct: 227 LTIKATCPMELQNFPMDRQSCPLVIGS 253 >UniRef50_Q19351 Cluster: Ligand-gated ion channel protein 3; n=3; Caenorhabditis|Rep: Ligand-gated ion channel protein 3 - Caenorhabditis elegans Length = 355 Score = 52.4 bits (120), Expect = 1e-05 Identities = 42/166 (25%), Positives = 77/166 (46%), Gaps = 5/166 (3%) Frame = +2 Query: 83 TCAIASAAECENATSLSLMIDSLLATYDRESPPDSKIVVNLTLHLRHA-NIRESESTVRI 259 T +A +E +S S + LL +++ SPPD ++ ++ + L H I E +++ Sbjct: 56 TVGVAEFSEQYQGSS-SRLTRHLLEKHNKCSPPDGRVDISHNIELVHIIGINELNQNMQV 114 Query: 260 LADLQMNWIDKRLSWSAGEW-GCS-TWLVSSERLWRPDVVLLNAAATTAGDYALRA--RV 427 L + W D LSW E+ G TWL +W PD+++ N A+R+ +V Sbjct: 115 LVYIVQQWTDASLSWKVEEFRGIKHTWL-PEHSIWIPDIIVFNTLEHKMLLEAVRSPIKV 173 Query: 428 SNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEM 565 S G V++ + + + +P D Q +F S ++ D++ Sbjct: 174 SYTGEVTYAYPAIYTVLCQIGIATFPFDDQVYV-QFASWAYDEDKI 218 >UniRef50_Q86YW4 Cluster: Ligand-gated ion channel subunit; n=10; Theria|Rep: Ligand-gated ion channel subunit - Homo sapiens (Human) Length = 411 Score = 52.4 bits (120), Expect = 1e-05 Identities = 27/101 (26%), Positives = 49/101 (48%) Frame = +2 Query: 269 LQMNWIDKRLSWSAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVS 448 L+++W+D RL+W+ + E LW P + +L A D + +ARV +G V Sbjct: 86 LRLSWLDTRLAWNTSAHPRHAITLPWESLWTPRLTILEALWVDWRDQSPQARVDQDGHVK 145 Query: 449 WIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDF 571 L T + +L ++P D C+ F + + + E++F Sbjct: 146 LNLALTTETNCNFELLHFPRDHSNCSLSFYALSNTAMELEF 186 >UniRef50_Q6Q069 Cluster: Neuronal nicotinic acetylcholine Apisa7-2 subunit; n=3; Apis mellifera|Rep: Neuronal nicotinic acetylcholine Apisa7-2 subunit - Apis mellifera (Honeybee) Length = 461 Score = 52.0 bits (119), Expect = 2e-05 Identities = 32/129 (24%), Positives = 56/129 (43%), Gaps = 3/129 (2%) Frame = +2 Query: 191 IVVNLTLHLRHANIRESESTVRILADLQMNWIDKRLSWSAGEW-GCSTWLVSSERLWRPD 367 +V L+LH ++ E + + W D L W+A E+ G V R+WRPD Sbjct: 33 VVFGLSLH-HIIDVDEKNQILTTNCWVTQIWTDHHLKWNASEFAGIRVIRVPYNRVWRPD 91 Query: 368 VVLLNAAATTAGDYALRARV--SNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 541 +L N A + V S+ G V W+ + + ++ +P D Q C K+ S Sbjct: 92 TILYNNADPQYSSAVINTNVIVSHTGEVVWLSHGIFRSSCDIDVEFFPFDEQRCVLKWAS 151 Query: 542 RMHNSDEMD 568 ++ +++ Sbjct: 152 WTYDGYQLE 160 >UniRef50_Q6F6K3 Cluster: Acetylcholine receptor protein 17, isoform b; n=4; Caenorhabditis|Rep: Acetylcholine receptor protein 17, isoform b - Caenorhabditis elegans Length = 515 Score = 52.0 bits (119), Expect = 2e-05 Identities = 33/152 (21%), Positives = 72/152 (47%), Gaps = 9/152 (5%) Frame = +2 Query: 137 MIDSLLATYDRESPP---DSKIVVNLTLHLRHANIR---ESESTVRILADLQMNWIDKRL 298 +I L Y +E P +S N+T+ L I+ E++ + + ++ W D+ L Sbjct: 27 LIKYLFRDYHKELRPVKDESSGPTNVTVQLYFKQIQKVHENDQIITLYCWIEEYWQDEFL 86 Query: 299 SWSAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYALR--ARVSNNGSVSWIKRLDI 469 +W+ ++G L V SE +W+PD+++ N A + ++ ++ + G +S + + Sbjct: 87 TWNPSDFGNIKSLHVPSEMIWKPDLLVYNNANMNIKENEMQTNVQIEHTGKISLFRAIIT 146 Query: 470 STPISMQLDNWPNDMQTCTFKFGSRMHNSDEM 565 +Q++ +P D Q C S ++ ++ Sbjct: 147 DITCDLQMEKFPYDQQICFIMLASWSYDGSQI 178 >UniRef50_Q2XWK7 Cluster: Nicotinic acetylcholine receptor subunit type F; n=1; Lymnaea stagnalis|Rep: Nicotinic acetylcholine receptor subunit type F - Lymnaea stagnalis (Great pond snail) Length = 488 Score = 52.0 bits (119), Expect = 2e-05 Identities = 29/101 (28%), Positives = 50/101 (49%), Gaps = 2/101 (1%) Frame = +2 Query: 272 QMNWIDKRLSWSAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYA-LRARVSNNGSV 445 + W D L W ++ T + + SE +W PD++L N A + VS++GS+ Sbjct: 97 EYTWSDVLLKWDIEQYDNITDVRIPSEHIWLPDILLYNFADDRLKEQRNALVVVSHDGSL 156 Query: 446 SWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 568 W+ + + + + +P D QTC KFGS +N ++D Sbjct: 157 LWMPQAILRSSCAFNTLYFPFDEQTCVLKFGSWSYNGFKLD 197 >UniRef50_A7S2N9 Cluster: Predicted protein; n=3; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 545 Score = 52.0 bits (119), Expect = 2e-05 Identities = 34/131 (25%), Positives = 70/131 (53%), Gaps = 5/131 (3%) Frame = +2 Query: 191 IVVNLTLHLRHANIRESESTVRILADLQMNWIDKRLSWSAGEWGCSTWL-VSSERLWRPD 367 +V+ +++H + ++ E + ++ ++ W + L W+ +G + VS ++W PD Sbjct: 77 VVLGMSVH-QIIDVYEKDQIIKTSFWVRQIWYNPFLRWNETFYGGIKEINVSPLQVWTPD 135 Query: 368 VVLLNAA-ATTAG---DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKF 535 +VL N A A+T G ++ R VS++G W+ + S+ ++++ +P D Q C+ KF Sbjct: 136 LVLYNNADASTDGSLENFKTRIIVSSDGKNMWLAPVIFSSSCTIKIKYFPFDDQYCSLKF 195 Query: 536 GSRMHNSDEMD 568 GS + +D Sbjct: 196 GSWTFDGFHLD 206 >UniRef50_UPI0000586C99 Cluster: PREDICTED: similar to nicotinic acetylcholine receptor subunit type A; n=1; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to nicotinic acetylcholine receptor subunit type A - Strongylocentrotus purpuratus Length = 357 Score = 51.6 bits (118), Expect = 2e-05 Identities = 35/124 (28%), Positives = 56/124 (45%), Gaps = 7/124 (5%) Frame = +2 Query: 281 WIDKRLSWSAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYALRAR----VSNNGSV 445 W D+ L W + T L + + ++W PD VL N + D + V ++GSV Sbjct: 130 WRDEYLMWEPRAYNNLTVLRIPASKIWLPDTVLYNTRQSN-NDQLMTVETLTIVKSDGSV 188 Query: 446 SWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDKRIYSMFE--SXAWD 619 W L + + S+ + +P D Q C K GS H+ +D+ +D S E + WD Sbjct: 189 DWSAPLTMISECSINVYYYPFDQQECALKMGSWQHDRKFIDY-LDGTADSATEQRNGEWD 247 Query: 620 VTDL 631 T + Sbjct: 248 TTSI 251 >UniRef50_Q22224 Cluster: Putative uncharacterized protein acr-14; n=2; Caenorhabditis|Rep: Putative uncharacterized protein acr-14 - Caenorhabditis elegans Length = 500 Score = 51.6 bits (118), Expect = 2e-05 Identities = 38/130 (29%), Positives = 62/130 (47%), Gaps = 9/130 (6%) Frame = +2 Query: 227 NIRESESTVRILADLQMNWIDKRLSWSAGEWG------CSTWLVSSERLWRPDVVLLNAA 388 ++ E + ILA + +W D +L+W +G S +S +LWRPDV+L N+ Sbjct: 59 DVDEKNQVMSILAYMDYHWNDYKLTWDPKLFGGIRDVRFSGDDDASFKLWRPDVLLFNSV 118 Query: 389 ATT-AGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSD-- 559 + + Y+ R VS+NG V + + +P D QTC K GS +N Sbjct: 119 SESFDSTYSSRFIVSSNGDVQQNPPGIFRFVCQIDVTYYPFDKQTCFLKLGSWTYNGQYI 178 Query: 560 EMDFVIDKRI 589 +DF++ + I Sbjct: 179 NLDFLLTQII 188 >UniRef50_P36544 Cluster: Neuronal acetylcholine receptor subunit alpha-7 precursor; n=65; Euteleostomi|Rep: Neuronal acetylcholine receptor subunit alpha-7 precursor - Homo sapiens (Human) Length = 502 Score = 51.6 bits (118), Expect = 2e-05 Identities = 30/124 (24%), Positives = 57/124 (45%), Gaps = 3/124 (2%) Frame = +2 Query: 269 LQMNWIDKRLSWSAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSNNGS 442 LQM+W D L W+ E+ G T ++W+PD++L N+A + V+++G Sbjct: 78 LQMSWTDHYLQWNVSEYPGVKTVRFPDGQIWKPDILLYNSADERFDATFHTNVLVNSSGH 137 Query: 443 VSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDKR-IYSMFESXAWD 619 ++ + + + +P D+Q C KFGS + +D + + I + WD Sbjct: 138 CQYLPPGIFKSSCYIDVRWFPFDVQHCKLKFGSWSYGGWSLDLQMQEADISGYIPNGEWD 197 Query: 620 VTDL 631 + + Sbjct: 198 LVGI 201 >UniRef50_UPI00015B6212 Cluster: PREDICTED: similar to nicotinic acetylcholine receptor alpha9 subunit; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to nicotinic acetylcholine receptor alpha9 subunit - Nasonia vitripennis Length = 443 Score = 51.2 bits (117), Expect = 3e-05 Identities = 47/174 (27%), Positives = 77/174 (44%), Gaps = 8/174 (4%) Frame = +2 Query: 83 TCAIASAAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHANIR-ESESTV 253 TC++A+A + L D YD P K N+++H I ES+ Sbjct: 29 TCSLAAAKSPHLRLNRYLFCD-----YDITVRPVIHHKNATNISIHFDPLRIDFMDESST 83 Query: 254 RILADLQM-NWIDKRLSWSAGEW-GCSTWLVSSERLWRPDVVLLNAA---ATTAGDYALR 418 IL +W+D+ L+W+ ++ G + V S ++W PD+ L N+A T G ++ Sbjct: 84 FILHTWNTWSWMDEFLTWNPKDFDGINETRVESAKIWTPDLALYNSADMTETQIGIPSVP 143 Query: 419 ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVID 580 + N+G + I + T + WP D QTC + S N+ +D ID Sbjct: 144 CILVNDGQLVCIAPVKYVTHCTTDFTYWPYDEQTCNIRLSS--WNNHALDINID 195 >UniRef50_Q6TMY3 Cluster: Nicotinic acetylcholine receptor alpha subunit precursor; n=4; Schistosoma|Rep: Nicotinic acetylcholine receptor alpha subunit precursor - Schistosoma haematobium (Blood fluke) Length = 714 Score = 51.2 bits (117), Expect = 3e-05 Identities = 33/140 (23%), Positives = 67/140 (47%), Gaps = 4/140 (2%) Frame = +2 Query: 164 DRESPPDSKIV-VNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWSAGEWGCSTWL 337 +R S D++ + V++ L ++ E + + + + W D W+ E+G T L Sbjct: 47 ERPSANDTETLNVSVKFFLNQVMDVDEKNQVLTTIIWMDLIWNDYHFLWNPKEFGNITTL 106 Query: 338 -VSSERLWRPDVVLLNAAATTAG-DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPND 511 + +WRPD++L N A + + ++G+V W+ + ++ + +P D Sbjct: 107 NLPYTAVWRPDILLYNCADEKFDRTFPTNTIIKHDGTVQWMPPGLFKSTCNIDILWFPFD 166 Query: 512 MQTCTFKFGSRMHNSDEMDF 571 Q+C KFGS + D+++F Sbjct: 167 EQSCILKFGSWTYYGDQINF 186 >UniRef50_A7SLK4 Cluster: Predicted protein; n=2; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 319 Score = 51.2 bits (117), Expect = 3e-05 Identities = 43/164 (26%), Positives = 81/164 (49%), Gaps = 11/164 (6%) Frame = +2 Query: 131 SLMIDSLLATYDRESPPDSK---IVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRL 298 +L++ +LL YDR P SK +VV + +++ + ++E I L+ W D+RL Sbjct: 23 TLVLKNLLEGYDRRIRPGSKGEPVVVYVDMYVSNIWAMQEMNMDFTIDIYLRQYWRDERL 82 Query: 299 SWSAGEWGCSTWLVS--SERLWRPDVVLLNAAAT-----TAGDYALRARVSNNGSVSWIK 457 + G L S ++++W P L T +Y L+ V +GS+ + Sbjct: 83 QFETQTPGAMLTLSSDINKQIWVPSTYFLATKKAYFHDVTTDNYLLQ--VKPDGSLFYSI 140 Query: 458 RLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDKRI 589 RL I+T + L ++P+D Q+C+ S + S ++ +V ++R+ Sbjct: 141 RLTITTSCRLDLRDFPHDTQSCSLSLESYGYQSTDVLYVWNERL 184 >UniRef50_A7RFJ2 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 278 Score = 51.2 bits (117), Expect = 3e-05 Identities = 32/130 (24%), Positives = 62/130 (47%), Gaps = 2/130 (1%) Frame = +2 Query: 191 IVVNLTLHLRH-ANIRESESTVRILADLQMNWIDKRLSWSAGEWGCSTWL-VSSERLWRP 364 I V + HL A + E E +++ ++ W + L W+ E+G T + V + +W P Sbjct: 31 ITVVFSAHLLGLAKVNEKEQSIKTHLWIKEEWYNPFLMWNPEEFGNITEIIVPANMIWVP 90 Query: 365 DVVLLNAAATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSR 544 D++L N +T + + ++ NG+ +W +T + + +P D QTC F S Sbjct: 91 DIILYNKGSTL---FNTKVIIAFNGNNTWRSPAIYNTMCVLDVKYFPFDEQTCDLVFASW 147 Query: 545 MHNSDEMDFV 574 + +++ V Sbjct: 148 TRDISKLNLV 157 >UniRef50_UPI0000E48474 Cluster: PREDICTED: similar to nicotinic acetylcholine receptor subunit type G, partial; n=1; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to nicotinic acetylcholine receptor subunit type G, partial - Strongylocentrotus purpuratus Length = 452 Score = 50.8 bits (116), Expect = 4e-05 Identities = 33/117 (28%), Positives = 55/117 (47%), Gaps = 7/117 (5%) Frame = +2 Query: 236 ESESTVRILADLQMNWIDKRLSWSAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYA 412 E + I ++ +W D++L W + G + + +W PDV L + A + DY Sbjct: 2 ERNQVLTINVWIEQHWDDEKLVWDPDAYEGIEILRIPATEIWLPDVTLYDNA--DSNDYV 59 Query: 413 LRARVSN-----NGSVS-WIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEM 565 +R SN +G V W K + + + + +P D Q C+ KFGS +NS +M Sbjct: 60 AHSRQSNALVNADGRVDLWSKPALVKSTCKIDVKFFPFDEQMCSMKFGSWTYNSFQM 116 >UniRef50_UPI0000E47329 Cluster: PREDICTED: similar to novel cholinergic receptor, nicotinic, alpha polypeptide protein; n=1; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to novel cholinergic receptor, nicotinic, alpha polypeptide protein - Strongylocentrotus purpuratus Length = 802 Score = 50.8 bits (116), Expect = 4e-05 Identities = 36/130 (27%), Positives = 60/130 (46%), Gaps = 5/130 (3%) Frame = +2 Query: 194 VVNLTLHLRHANIRESESTVRILAD---LQMNWIDKRLSWSAGEWGCSTWL-VSSERLWR 361 ++N++ L + I + + ++L ++ W D RL W E+G T + V +E LW Sbjct: 421 ILNVSFGLSISQIIDLDERNQVLTSKVWVKQQWRDYRLQWEPEEYGGITKIKVPNECLWI 480 Query: 362 PDVVLLNAAATTAG-DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFG 538 PD++L N A A A + G V+W + + + +P D Q C KFG Sbjct: 481 PDILLYNNADGAFDIQSASWAGIDYTGLVTWWPPAVYKSSCQINVAYYPFDEQHCLLKFG 540 Query: 539 SRMHNSDEMD 568 S ++ MD Sbjct: 541 SWTYDGVVMD 550 >UniRef50_Q9GQU9 Cluster: Nicotinic acetylcholine receptor-like subunit ACR-12; n=2; Caenorhabditis|Rep: Nicotinic acetylcholine receptor-like subunit ACR-12 - Caenorhabditis elegans Length = 573 Score = 50.8 bits (116), Expect = 4e-05 Identities = 33/120 (27%), Positives = 56/120 (46%), Gaps = 2/120 (1%) Frame = +2 Query: 215 LRHANIRESESTVRILADLQMNWIDKRLSWSAGEWG-CSTWLVSSERLWRPDVVLLNAAA 391 +R ++ E + L+M W D +L+W+ ++G T + S+ +W PD+VL N AA Sbjct: 72 IRIIDVDEKNQVLTTNLWLEMKWNDAKLTWTPEKYGGLKTLHIPSDFIWTPDLVLYNNAA 131 Query: 392 TTAGDYALR-ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 568 L A V+ G+V W + + + +P D Q C KFG+ + +D Sbjct: 132 GDPDITILTDALVTFEGNVYWQPPAIYKSFCPIDVTWFPYDSQKCEMKFGTWTYTGRYVD 191 >UniRef50_UPI0000E473D1 Cluster: PREDICTED: similar to neuronal acetylcholine receptor subunit alpha-9 precursor; n=2; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to neuronal acetylcholine receptor subunit alpha-9 precursor - Strongylocentrotus purpuratus Length = 510 Score = 50.4 bits (115), Expect = 5e-05 Identities = 26/110 (23%), Positives = 56/110 (50%), Gaps = 2/110 (1%) Frame = +2 Query: 236 ESESTVRILADLQMNWIDKRLSWSAGEWG-CSTWLVSSERLWRPDVVLL-NAAATTAGDY 409 E + V++ + +W D+ L W ++G T S + +W+PD+ L+ N ++ Sbjct: 140 ERKQHVQLSGWRRQDWRDEFLQWDPDDYGGLETITFSKDGIWKPDITLIENVNQDFINEF 199 Query: 410 ALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSD 559 + V+ +GSV+W + +++ + + +P D QTC + S ++S+ Sbjct: 200 SADVIVTYDGSVTWFTPIILTSACMVGVRYFPFDFQTCQMTYMSWAYDSN 249 >UniRef50_Q9VPQ8 Cluster: CG11822-PA, isoform A (Nicotinic acetylcholine receptor beta subunit) (Nicotinic acetylcholine receptor beta 3 (Dbeta3) subunit); n=4; Sophophora|Rep: CG11822-PA, isoform A (Nicotinic acetylcholine receptor beta subunit) (Nicotinic acetylcholine receptor beta 3 (Dbeta3) subunit) - Drosophila melanogaster (Fruit fly) Length = 441 Score = 50.4 bits (115), Expect = 5e-05 Identities = 34/147 (23%), Positives = 62/147 (42%), Gaps = 5/147 (3%) Frame = +2 Query: 116 NATSLSLMIDSLLATYDRESPP---DSKIVVNLTLHLRHANIRESESTVRILADLQMNWI 286 N +L + L YD + P + V+L + + + +I E + L + W Sbjct: 47 NVKALDRLHAGLFTNYDSDVQPVFQGTPTNVSLEMVVTYIDIDELNGKLTTHCWLNLRWR 106 Query: 287 DKRLSWSAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYA-LRARVSNNGSVSWIKR 460 D+ W ++ T + + S +W P + L N G A + +S++G W+ Sbjct: 107 DEERVWQPSQYDNITQITLKSSEVWTPQITLFNG--DEGGLMAETQVTLSHDGHFRWMPP 164 Query: 461 LDISTPISMQLDNWPNDMQTCTFKFGS 541 + + + NWP+D Q+C K GS Sbjct: 165 AVYTAYCELNMLNWPHDKQSCKLKIGS 191 >UniRef50_A7S2P0 Cluster: Predicted protein; n=4; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 541 Score = 50.4 bits (115), Expect = 5e-05 Identities = 32/154 (20%), Positives = 72/154 (46%), Gaps = 10/154 (6%) Frame = +2 Query: 137 MIDSLLATYDRESPP----DSKIVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLS 301 ++ + +YD + P + V L L L ++ E + + ++ W + ++ Sbjct: 72 LLADVFGSYDNKLRPVLSKTHNVTVKLGLTLNQIMDVIEKFELLSVSLYVRQKWENPLVA 131 Query: 302 WSAGEWGCSTWL-VSSERLWRPDVVLLNAAAT----TAGDYALRARVSNNGSVSWIKRLD 466 W+ E+G + + LW+PD+ L N A + + + + +V+ +G+ +W+ Sbjct: 132 WNKSEYGGIVQVNLDPSTLWKPDIYLYNNADSGYDGSLYGFTAKIKVNYSGTNTWLAPKI 191 Query: 467 ISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 568 +T + + +P D Q C KFGS ++++ +D Sbjct: 192 FTTSCKINVKYFPFDQQECRLKFGSWTYDANSVD 225 >UniRef50_P34903 Cluster: Gamma-aminobutyric acid receptor subunit alpha-3 precursor (GABA(A) receptor subunit alpha-3); n=94; Euteleostomi|Rep: Gamma-aminobutyric acid receptor subunit alpha-3 precursor (GABA(A) receptor subunit alpha-3) - Homo sapiens (Human) Length = 492 Score = 50.4 bits (115), Expect = 5e-05 Identities = 36/158 (22%), Positives = 69/158 (43%), Gaps = 7/158 (4%) Frame = +2 Query: 113 ENATSLSLMIDSLLATYDRESPP---DSKIVVNLTLHLRHAN-IRESESTVRILADLQMN 280 +N T + ++D LL YD P D+ V +++ + +++ I + Sbjct: 62 DNITIFTRILDRLLDGYDNRLRPGLGDAVTEVKTDIYVTSFGPVSDTDMEYTIDVFFRQT 121 Query: 281 WIDKRLSWSAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSW 451 W D+RL + + + ++W PD N + A + R+ +NG++ + Sbjct: 122 WHDERLKFDGPMKILPLNNLLASKIWTPDTFFHNGKKSVAHNMTTPNKLLRLVDNGTLLY 181 Query: 452 IKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEM 565 RL I M L+++P D+ C KFGS + + E+ Sbjct: 182 TMRLTIHAECPMHLEDFPMDVHACPLKFGSYAYTTAEV 219 >UniRef50_Q621V5 Cluster: Putative uncharacterized protein CBG02331; n=1; Caenorhabditis briggsae|Rep: Putative uncharacterized protein CBG02331 - Caenorhabditis briggsae Length = 472 Score = 50.0 bits (114), Expect = 7e-05 Identities = 44/151 (29%), Positives = 71/151 (47%), Gaps = 9/151 (5%) Frame = +2 Query: 140 IDSLLATYDRESPPDSKIVVNLTLHLRHANIRE-SESTVRILADLQMN--WIDKRLSWSA 310 + LL YD+ P + V +++ L +I SE + +AD+ + W D RL + Sbjct: 75 LSDLLQDYDKTMVPSNNSV-QVSVELTVQDISSISEISSSFIADVWFSQVWEDPRLEYRN 133 Query: 311 GEWGCSTWLVS--SERLWRPDVVLLNAAATTAGDYA---LRARVSNNGSVSWIK-RLDIS 472 + L S SERLW P+V +N+ +T + + NG+V W+ R+ +S Sbjct: 134 ISCKTNLSLDSYVSERLWTPNVCFVNSKSTQVHKSPASNILLIIYPNGTV-WLNYRVQVS 192 Query: 473 TPISMQLDNWPNDMQTCTFKFGSRMHNSDEM 565 P S +L +P D Q C F S +N E+ Sbjct: 193 APCSFELSRFPIDAQECHLVFESYSYNIAEV 223 >UniRef50_A7RR86 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 479 Score = 50.0 bits (114), Expect = 7e-05 Identities = 31/138 (22%), Positives = 65/138 (47%), Gaps = 8/138 (5%) Frame = +2 Query: 197 VNLTLHLRHANIRESESTVRILAD---LQMNWIDKRLSWSAGEWGCSTWL-VSSERLWRP 364 + + + A + E +S +I+ ++ W + RL W ++G T + +S +W P Sbjct: 58 IKVIFDIAFAQLVELDSKNQIMTSYIWVRQFWSNTRLRWDPSKYGGQTSVNLSPHLIWLP 117 Query: 365 DVVLLNAA-ATTAGD---YALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFK 532 D+VL N + T G+ + + + N G++ W + + + + +P D Q C+ Sbjct: 118 DIVLYNNINSNTIGEMFKFDTKVVLHNTGAIEWYAPTLVKSICKIDITYFPFDKQNCSLV 177 Query: 533 FGSRMHNSDEMDFVIDKR 586 FGS + S+ + I ++ Sbjct: 178 FGSWTYTSEFLSLDIKQK 195 >UniRef50_P02708 Cluster: Acetylcholine receptor subunit alpha precursor; n=142; Coelomata|Rep: Acetylcholine receptor subunit alpha precursor - Homo sapiens (Human) Length = 482 Score = 50.0 bits (114), Expect = 7e-05 Identities = 26/92 (28%), Positives = 48/92 (52%), Gaps = 5/92 (5%) Frame = +2 Query: 281 WIDKRLSWSAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNGSV 445 W+D L W+ ++G + + SE++WRPD+VL N A GD+A+ + + G + Sbjct: 105 WVDYNLKWNPDDYGGVKKIHIPSEKIWRPDLVLYNNA---DGDFAIVKFTKVLLQYTGHI 161 Query: 446 SWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 541 +W + + + ++P D Q C+ K G+ Sbjct: 162 TWTPPAIFKSYCEIIVTHFPFDEQNCSMKLGT 193 >UniRef50_Q4RR58 Cluster: Chromosome 14 SCAF15003, whole genome shotgun sequence; n=1; Tetraodon nigroviridis|Rep: Chromosome 14 SCAF15003, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 470 Score = 49.6 bits (113), Expect = 9e-05 Identities = 36/141 (25%), Positives = 65/141 (46%), Gaps = 7/141 (4%) Frame = +2 Query: 137 MIDSLLATYDRESPPDSKI--VVNLTLHLRHANIRESESTVRILAD---LQMNWIDKRLS 301 + L A Y++ S P + VV + L A + + + +++ L+ W D +L Sbjct: 7 LFKKLFAGYNKYSRPVPNVTDVVIVKFGLSIAQLIDVDEKNQMMTTNVWLKQEWNDYKLR 66 Query: 302 WSAGEWGCSTWL-VSSERLWRPDVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDIST 475 W ++ T + V SE +W PD+VL N A A + +A + +NG + W+ ++ Sbjct: 67 WRPSDYDNVTSIRVPSELIWVPDIVLYNNADGEFAVTHMTKAHLFHNGKIRWVPPAIYNS 126 Query: 476 PISMQLDNWPNDMQTCTFKFG 538 + + +P D T KFG Sbjct: 127 SCIIDVTFFPFDQHTARCKFG 147 >UniRef50_A7RND6 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 254 Score = 49.6 bits (113), Expect = 9e-05 Identities = 27/99 (27%), Positives = 49/99 (49%), Gaps = 1/99 (1%) Frame = +2 Query: 281 WIDKRLSWSAGEWGCSTWLVSS-ERLWRPDVVLLNAAATTAGDYALRARVSNNGSVSWIK 457 W D RL+W+ E+G ++L +++W PD++L A G RA +++ G V + Sbjct: 3 WKDPRLTWNPTEFGNISYLTMKVDKIWSPDMML--TLADIPGSLEFRAIITHEGLVKIFQ 60 Query: 458 RLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFV 574 IST + + +P D TC + G N+ ++ + Sbjct: 61 PTSISTTCEVNIAFYPFDEHTCFIEIGPWSMNTAAVNVI 99 >UniRef50_UPI000069FF34 Cluster: UPI000069FF34 related cluster; n=1; Xenopus tropicalis|Rep: UPI000069FF34 UniRef100 entry - Xenopus tropicalis Length = 356 Score = 49.2 bits (112), Expect = 1e-04 Identities = 27/91 (29%), Positives = 43/91 (47%), Gaps = 1/91 (1%) Frame = +2 Query: 269 LQMNWIDKRLSWSAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 445 L W ++ LSW + E+ G S + +W PD+ + + D L + NNG+V Sbjct: 3 LLQTWENQLLSWDSEEFCGISRVSIPESTIWIPDIYISETIEDNSLD-VLYVHLYNNGTV 61 Query: 446 SWIKRLDISTPISMQLDNWPNDMQTCTFKFG 538 K L++ T ++ L +P D Q C FG Sbjct: 62 QRTKTLNVMTTCTLDLYKFPFDEQKCNLTFG 92 >UniRef50_Q9W288 Cluster: CG6698-PA; n=4; Sophophora|Rep: CG6698-PA - Drosophila melanogaster (Fruit fly) Length = 585 Score = 49.2 bits (112), Expect = 1e-04 Identities = 31/143 (21%), Positives = 63/143 (44%), Gaps = 4/143 (2%) Frame = +2 Query: 122 TSLSLMIDSLLATYDRESPPDSKIVVNLTLHLRHANIRESESTVRILADLQMNWIDKRLS 301 T ++ L + S P + ++ R ++ S ++ + M+W D RL Sbjct: 214 TKTEKLLSHLNIQAENASMPANLSSISFHFQTRSLAYEQTSSLLQTRMHMMMHWRDSRLV 273 Query: 302 WSAGEWG-CSTWLVSSERLWRPDVVLLNAAATTAGD--YALRARVSNNGSVS-WIKRLDI 469 W ++G ++ R+W+P + +LN A + G + V NGS++ + + L + Sbjct: 274 WKPEDFGSLESFEHPDLRIWKPHMNVLNGALQSMGQVLQSYELMVYANGSITLYAQNLQL 333 Query: 470 STPISMQLDNWPNDMQTCTFKFG 538 ++ NWP++ TC + G Sbjct: 334 ASWCVDSARNWPSERVTCDIELG 356 >UniRef50_Q14DU4 Cluster: CHRNG protein; n=3; Euarchontoglires|Rep: CHRNG protein - Homo sapiens (Human) Length = 465 Score = 49.2 bits (112), Expect = 1e-04 Identities = 33/113 (29%), Positives = 53/113 (46%), Gaps = 7/113 (6%) Frame = +2 Query: 137 MIDSLLATYDRESPPDSKI--VVNLTLHLRHANI---RESESTVRILADLQMNWIDKRLS 301 ++ L+ YD P + VVN++L L N+ E E + ++M W D RL Sbjct: 29 LLADLMQNYDPNLRPAERDSDVVNVSLKLTLTNLISLNEREEALTTNVWIEMQWCDYRLR 88 Query: 302 WSAGEW-GCSTWLVSSERLWRPDVVLLNAAAT-TAGDYALRARVSNNGSVSWI 454 W ++ G V S +WRPD+VL N + T + + L+ + S+ WI Sbjct: 89 WDPRDYEGLWVLRVPSTMVWRPDIVLENKSQTYSTNEIDLQLSQEDGQSIEWI 141 >UniRef50_Q99928 Cluster: Gamma-aminobutyric acid receptor subunit gamma-3 precursor (GABA(A) receptor subunit gamma-3); n=106; Euteleostomi|Rep: Gamma-aminobutyric acid receptor subunit gamma-3 precursor (GABA(A) receptor subunit gamma-3) - Homo sapiens (Human) Length = 467 Score = 49.2 bits (112), Expect = 1e-04 Identities = 38/172 (22%), Positives = 73/172 (42%), Gaps = 7/172 (4%) Frame = +2 Query: 122 TSLSLMIDSLLATYDRESPPDSKI---VVNLTLHLRHAN-IRESESTVRILADLQMNWID 289 T ++L+++ LL YD++ PD I V+++ +++ + +I W D Sbjct: 45 TDVTLILNKLLREYDKKLRPDIGIKPTVIDVDIYVNSIGPVSSINMEYQIDIFFAQTWTD 104 Query: 290 KRLSWSAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKR 460 RL +++ + +W PD + N+ A R+ N+G + + R Sbjct: 105 SRLRFNSTMKILTLNSNMVGLIWIPDTIFRNSKTAEAHWITTPNQLLRIWNDGKILYTLR 164 Query: 461 LDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDKRIYSMFESXAW 616 L I+ +QL N+P D +C F S + +EM + K + +W Sbjct: 165 LTINAECQLQLHNFPMDEHSCPLIFSSYGYPKEEMIYRWRKNSVEAADQKSW 216 >UniRef50_UPI000069F132 Cluster: 5-hydroxytryptamine receptor 3 subunit D; n=3; Euteleostomi|Rep: 5-hydroxytryptamine receptor 3 subunit D - Xenopus tropicalis Length = 415 Score = 48.8 bits (111), Expect = 2e-04 Identities = 29/118 (24%), Positives = 53/118 (44%), Gaps = 2/118 (1%) Frame = +2 Query: 194 VVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWSAGEWG-CSTWLVSSERLWRPD 367 VVN+++ + + E + + L M W ++ W G V +E +W PD Sbjct: 11 VVNISITVYAILGVNEKDQLLTSFLWLTMVWFNEFAEWEPALCGGVQNISVPAEEMWIPD 70 Query: 368 VVLLNAAATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 541 + +L + V +NG V ++K L + + ++ + +P D+Q CT FGS Sbjct: 71 IFVLQFVDEDKSPHLPYLLVDHNGRVRFLKPLRVVSSCNLSIFRFPFDIQNCTLTFGS 128 >UniRef50_UPI00006602DC Cluster: Homolog of Homo sapiens "5-hydroxytryptamine 3 receptor B subunit; n=1; Takifugu rubripes|Rep: Homolog of Homo sapiens "5-hydroxytryptamine 3 receptor B subunit - Takifugu rubripes Length = 271 Score = 48.8 bits (111), Expect = 2e-04 Identities = 29/95 (30%), Positives = 49/95 (51%), Gaps = 2/95 (2%) Frame = +2 Query: 281 WIDKRLSWSAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDY-ALRARVSNNGSVSWI 454 W ++ L+W++ + G VS LW PD+V+ + T+ +Y + A +S+NG V Sbjct: 55 WKNEFLAWNSSVFCGMELLPVSLSLLWVPDIVIREDVSDTSSNYMSPLATLSSNGWVHSS 114 Query: 455 KRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSD 559 R +++ + L +P DMQ C FGS + D Sbjct: 115 LRHVLTSTCKLDLKLFPFDMQICNLSFGSMSFSDD 149 >UniRef50_O44452 Cluster: Putative uncharacterized protein; n=2; Caenorhabditis|Rep: Putative uncharacterized protein - Caenorhabditis elegans Length = 464 Score = 48.8 bits (111), Expect = 2e-04 Identities = 40/176 (22%), Positives = 77/176 (43%), Gaps = 10/176 (5%) Frame = +2 Query: 137 MIDSLLATYDRESPPDSK----IVVNLTLHLRH-ANIRESESTVRILADLQMNWIDKRLS 301 +I+++ YD+ P ++ ++V++T+ L +RE++ + W D +L+ Sbjct: 44 LIETIQRRYDKRVRPFAESNRPVIVHMTIVLGILTEVRENQQVASFVISHVQKWRDPKLA 103 Query: 302 WSAGEWGCSTWLVSSERL-WRPDVVLLNAAATT--AGDYALRARVSNNGSVSWIKRLDIS 472 W+ + T +V L W P + + N+ T D R+ + G V +S Sbjct: 104 WNPADHSGLTQVVMPRSLVWVPKLFIYNSMDTKDMLTDDRYDVRIQHTGHVKVNSPQFVS 163 Query: 473 TPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDF-VIDKRIYSMFESXA-WDVTDLS 634 T + +D +P D Q C S + + +EMD + S F A W V +++ Sbjct: 164 TLCRINIDLFPFDTQFCAIALASPLLSVEEMDVNATQPPVDSYFSGNAEWQVMNVT 219 >UniRef50_A7S6R3 Cluster: Predicted protein; n=3; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 409 Score = 48.8 bits (111), Expect = 2e-04 Identities = 43/161 (26%), Positives = 74/161 (45%), Gaps = 5/161 (3%) Frame = +2 Query: 104 AECENATSLS-LMIDSLLATYDRESPPDS---KIVVNLTLHLR-HANIRESESTVRILAD 268 +E NAT L M+ S + YDR++ P++ + V L++ ++ +I+E+ Sbjct: 37 SEIINATRLQERMLSS--SNYDRKARPNAGKEPLDVYLSIGVQAFTSIKETNMEFTTSLF 94 Query: 269 LQMNWIDKRLSWSAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVS 448 L+ W D RL+ + S V ++WRPD + N A +S G V Sbjct: 95 LRQEWTDIRLAHGL-DGTISLGGVEVNQIWRPDTYINNNNDYELHVENQLALISKYGDVY 153 Query: 449 WIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDF 571 + R+ + M L N+P D+Q C+ F S + +D + F Sbjct: 154 FSARMLVRASCQMYLQNFPMDVQKCSLVFESFAYTNDHVAF 194 >UniRef50_P41849 Cluster: Uncharacterized glycine receptor-like protein T20B12.9; n=2; Caenorhabditis|Rep: Uncharacterized glycine receptor-like protein T20B12.9 - Caenorhabditis elegans Length = 476 Score = 48.8 bits (111), Expect = 2e-04 Identities = 46/164 (28%), Positives = 78/164 (47%), Gaps = 11/164 (6%) Frame = +2 Query: 107 ECENATSLSLMIDSLLATYDRESPPDSKIVVNLTLHLRHANIRE-SESTVRILADLQMN- 280 E + +L +ID+LL YD P+++ VN+T+ L + SE T D+ + Sbjct: 9 EFNSRINLGKLIDTLLTDYDTHLLPEAE-GVNVTIELHVQGVSGISEITGDFSLDVMYSE 67 Query: 281 -WIDKRLSWSAGEWGCSTWL---VSS--ERLWRPDVVLLNAAATTAGDYALRAR---VSN 433 W D RLS+ C+T + VS +++W PD ++N+ +++ + Sbjct: 68 IWQDPRLSFKHLNV-CATNITLKVSDFRKKIWTPDTCIINSKSSSIHSSPSENTFVILYE 126 Query: 434 NGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEM 565 NG V RL++ TP S+ L +P D +C S N+DE+ Sbjct: 127 NGLVWSNFRLNVKTPCSVNLKMFPFDSLSCEIVLESYSFNTDEV 170 >UniRef50_O18276 Cluster: Gamma-aminobutyric acid receptor subunit beta precursor (GABA(A) receptor subunit beta); n=3; Rhabditida|Rep: Gamma-aminobutyric acid receptor subunit beta precursor (GABA(A) receptor subunit beta) - Caenorhabditis elegans Length = 550 Score = 48.8 bits (111), Expect = 2e-04 Identities = 44/158 (27%), Positives = 71/158 (44%), Gaps = 10/158 (6%) Frame = +2 Query: 122 TSLSLMIDSLLATYD-RESPPDSKIVVNLTLHLRHAN---IRESESTVRILADLQMNWID 289 ++ S ++ LL YD R P + LT+ + A+ I E + + L W D Sbjct: 52 SNASSLLSDLLLDYDIRLRPGFGGDALLLTMDIIIASFDSISEVDMDYTLTMYLHQYWTD 111 Query: 290 KRLSWSAGEWGCSTWLVS---SERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSW 451 +RL WS E +S S+ +W PD L N + + R R++ +G V++ Sbjct: 112 ERLRWS-NEIPIDEMTLSGEFSQNIWVPDTFLANDKHSYLHEVTERNKMLRINVDGKVAY 170 Query: 452 IKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEM 565 RL + SM L N+P D Q CT + S + + E+ Sbjct: 171 GMRLTSTLSCSMNLRNFPLDSQNCTVEIESYGYTTSEV 208 >UniRef50_A7S9T8 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 390 Score = 48.4 bits (110), Expect = 2e-04 Identities = 29/105 (27%), Positives = 45/105 (42%), Gaps = 5/105 (4%) Frame = +2 Query: 269 LQMNWIDKRLSWSAGEWGCSTWL-VSSERLWRPDVVLLNAA--ATTAGDYALRARVS--N 433 ++ W D L W + G T + V LW+PD+VL N Y +V + Sbjct: 13 VRQTWTDAWLKWDPAKHGGITAINVDPSFLWKPDMVLYNNVNDEDRGEQYLFNTKVIIYS 72 Query: 434 NGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 568 G + W + T + + +P D QTC FGS +N ++D Sbjct: 73 TGDIEWYSPNILKTHCKIDIQYFPFDTQTCKLTFGSWTYNGLKID 117 >UniRef50_A6XBS1 Cluster: Amorphous calcium carbonate binding protein 1; n=1; Pinctada fucata|Rep: Amorphous calcium carbonate binding protein 1 - Pinctada fucata (Pearl oyster) Length = 240 Score = 48.4 bits (110), Expect = 2e-04 Identities = 48/171 (28%), Positives = 76/171 (44%), Gaps = 10/171 (5%) Frame = +2 Query: 86 CAIASAAECENATSLSLMIDSLLATYD---RESPPDSKI-VVNLTLHLRHANIRESEST- 250 C + SA + + ++ LL Y+ R P D VV++ L H + +S+S Sbjct: 16 CVLFSAVVAKCDYPEAKLLKFLLDDYEKLVRPVPKDGNATVVSMGFSLNHIDDYDSDSME 75 Query: 251 VRILADLQMNWIDKRLSWS--AGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDY--AL 415 ++ A L + W D RL+W+ G +G L + +W PDVVLLN + L Sbjct: 76 LKSNAWLSLKWNDPRLTWNKDGGPFGNVKALHLPPSDIWVPDVVLLNGLQPFQPQFPDRL 135 Query: 416 RARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 568 A V + G + I + T + D D TC FKF S ++ E++ Sbjct: 136 TALVKDTGDIYLITPSVLETRCTP--DKADGDKATCRFKFMSWTYDGGEVE 184 >UniRef50_UPI0000E47720 Cluster: PREDICTED: similar to alpha-9 nicotinic acetylcholine receptor subunit precursor; n=4; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to alpha-9 nicotinic acetylcholine receptor subunit precursor - Strongylocentrotus purpuratus Length = 572 Score = 48.0 bits (109), Expect = 3e-04 Identities = 28/101 (27%), Positives = 45/101 (44%), Gaps = 2/101 (1%) Frame = +2 Query: 281 WIDKRLSWSAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYA-LRARVSNNGSVSWI 454 W D+ + W ++ G V +W PD+ L YA VS+NG++ W Sbjct: 193 WTDENMIWDPLDFDGVDYVTVKKNDVWLPDICLYQNVVKDFISYADTYIVVSSNGTMDWY 252 Query: 455 KRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVI 577 + I+T + + +P D+Q C FG N+D + F I Sbjct: 253 VPVIIATSCPIDITYFPYDVQHCNLTFGPWTLNTDRVRFQI 293 >UniRef50_UPI00003CEF8B Cluster: R03E1.3; n=1; Caenorhabditis elegans|Rep: R03E1.3 - Caenorhabditis elegans Length = 467 Score = 48.0 bits (109), Expect = 3e-04 Identities = 29/111 (26%), Positives = 46/111 (41%), Gaps = 4/111 (3%) Frame = +2 Query: 197 VNLTLHLRHAN-IRESESTVRILADLQMNWIDKRLSWSAGEWGCSTWLVSSERLWRPDVV 373 VN+ L + H + E E T + + WID+ + W A + + +S+ LW+P + Sbjct: 54 VNVFLSIAHVEKVDEHEQTALVHGHIWATWIDEYMQWDAKKENVTKLTISAHSLWQPALA 113 Query: 374 LLNAAATTAGDY---ALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQ 517 L N+A + A+ A V + G V NWP D Q Sbjct: 114 LYNSARGNSWHLYMGAMPATVYSTGKVWSTGTFSFYVTCQFDFTNWPFDQQ 164 >UniRef50_Q9GUF0 Cluster: Ligand-gated ion channel protein 10; n=3; Caenorhabditis|Rep: Ligand-gated ion channel protein 10 - Caenorhabditis elegans Length = 493 Score = 48.0 bits (109), Expect = 3e-04 Identities = 40/165 (24%), Positives = 72/165 (43%), Gaps = 10/165 (6%) Frame = +2 Query: 101 AAECENATSL----SLMIDSLLATYDRESPP--DSKIVVNLTLHLRHA-NIRESESTVRI 259 A CEN +L S +++ + YDR P ++VN+T+ L ++E++ Sbjct: 57 ALNCENFRTLDNETSAILNDIFVGYDRRVLPFVQGPVLVNMTIVLGILIELKENQQLAAY 116 Query: 260 LADLQMNWIDKRLSWSAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRA--RVS 430 + W D RLSW ++ G +V +W P + + N+ + RA R+ Sbjct: 117 VISHTQRWYDGRLSWDPSKYRGQREVIVPQTMVWIPKLFVYNSLESKDMLTENRADVRLY 176 Query: 431 NNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEM 565 +NG + + +Q +++P D Q C S + N +EM Sbjct: 177 HNGRIKINIPQYVQAICRIQTESFPFDCQFCAVALASPLLNVNEM 221 >UniRef50_Q6BET0 Cluster: Putative uncharacterized protein; n=2; Caenorhabditis|Rep: Putative uncharacterized protein - Caenorhabditis elegans Length = 536 Score = 48.0 bits (109), Expect = 3e-04 Identities = 32/163 (19%), Positives = 71/163 (43%), Gaps = 12/163 (7%) Frame = +2 Query: 119 ATSLSLMIDSLLATYDRESPPD------SKIVVNLTLHLRHANIRESESTVRILADLQMN 280 A +++ +++++L YD+ P +K+ ++L + + + +T + Sbjct: 59 AQNVTHLLNNVLKNYDQHFRPGFNSGKPTKVYIDLFIRTM-GPVSDLFNTYSFNCYFRQK 117 Query: 281 WIDKRLSWSAGEWG---CSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGS 442 W D RL ++ G S + +++W+PD N A + R+ +G+ Sbjct: 118 WTDDRLHFNNSGIGFRQLSLSMAMLDKIWKPDTYFWNGAGSYVHGITTSNRLVRLEPDGT 177 Query: 443 VSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDF 571 + + R+ + M + +P D Q C GS ++SDE+ + Sbjct: 178 ILYSSRITVKAKCQMDMSRYPLDKQACRLVIGSYAYSSDEVQY 220 >UniRef50_P48169 Cluster: Gamma-aminobutyric acid receptor subunit alpha-4 precursor (GABA(A) receptor subunit alpha-4); n=26; Euteleostomi|Rep: Gamma-aminobutyric acid receptor subunit alpha-4 precursor (GABA(A) receptor subunit alpha-4) - Homo sapiens (Human) Length = 554 Score = 48.0 bits (109), Expect = 3e-04 Identities = 32/119 (26%), Positives = 51/119 (42%), Gaps = 3/119 (2%) Frame = +2 Query: 236 ESESTVRILADLQMNWIDKRLSWSAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYAL 415 E E T+ + + WIDKRL + + ++W PD N + + + Sbjct: 90 EMEYTMDVF--FRQTWIDKRLKYDGPIEILRLNNMMVTKVWTPDTFFRNGKKSVSHNMTA 147 Query: 416 RA---RVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDK 583 R+ NG++ + RL IS M+L ++P D C KFGS + EM + K Sbjct: 148 PNKLFRIMRNGTILYTMRLTISAECPMRLVDFPMDGHACPLKFGSYAYPKSEMIYTWTK 206 >UniRef50_UPI0000E20C28 Cluster: PREDICTED: gamma-aminobutyric acid A receptor, alpha 6 isoform 1; n=1; Pan troglodytes|Rep: PREDICTED: gamma-aminobutyric acid A receptor, alpha 6 isoform 1 - Pan troglodytes Length = 478 Score = 47.6 bits (108), Expect = 4e-04 Identities = 38/164 (23%), Positives = 69/164 (42%), Gaps = 8/164 (4%) Frame = +2 Query: 125 SLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESESTVRILADLQMNWIDK 292 ++S ++D+LL YD P + V +++ + + E + + W D+ Sbjct: 31 NVSRILDNLLEGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTDE 90 Query: 293 RLSWSAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRA---RVSNNGSVSWIKRL 463 RL + S + ++W PD N + A + R+ NG++ + RL Sbjct: 91 RLKFGGPTEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTMRL 150 Query: 464 DISTPISMQLDNWPNDMQTCTFKFGS-RMHNSDEMDFVIDKRIY 592 I+ M+L N+P D C KFGS +H + D + +Y Sbjct: 151 TINADCPMRLVNFPMDGHACPLKFGSYNVHFEGKKDNSSNSLLY 194 >UniRef50_A2TM50 Cluster: Nicotinic acetylcholine receptor alpha 4 subunit; n=4; Aphidinae|Rep: Nicotinic acetylcholine receptor alpha 4 subunit - Sitobion avenae (English grain aphid) Length = 532 Score = 47.6 bits (108), Expect = 4e-04 Identities = 40/154 (25%), Positives = 67/154 (43%), Gaps = 10/154 (6%) Frame = +2 Query: 137 MIDSLLATYDRESPPDSKIVVNLTLHLRHANIRESESTVRILADLQMNWI-----DKRLS 301 + D LL+ Y+R P NLT+ + + +E ++ W+ D L Sbjct: 34 LFDDLLSNYNRLIRPVQNHSENLTVWMGLKLTQLTEMNLKSQVMTTSVWLIQKRFDCNLK 93 Query: 302 WSAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNGSVSWIKRLD 466 W ++G L V S+ +W PD+VL N A G+Y + +A + G V W Sbjct: 94 WDPKDYGGLDKLYVPSDHIWLPDIVLFNNA---DGNYEVTLMTKAVLKYTGEVLWSPPAI 150 Query: 467 ISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 568 + + + +P D Q C FGS +N +++D Sbjct: 151 YKSYCEINVLYFPFDEQNCYMMFGSWTYNGNQVD 184 >UniRef50_Q4RN70 Cluster: Chromosome undetermined SCAF15016, whole genome shotgun sequence; n=22; Eukaryota|Rep: Chromosome undetermined SCAF15016, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 269 Score = 47.2 bits (107), Expect = 5e-04 Identities = 40/163 (24%), Positives = 71/163 (43%), Gaps = 7/163 (4%) Frame = +2 Query: 104 AECENATSLSLMIDSLLATYDRESPP---DSKIVVNLTLHLRHAN-IRESESTVRILADL 271 AE + L I L+ Y++ P + + V ++L + + I E L Sbjct: 17 AEVKEGEILPPTIQRLMKGYNKYLRPFFDNGPVTVGMSLDIASIDTISEINMDYTATIFL 76 Query: 272 QMNWIDKRLSWSAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGS 442 + W D+RL + G S E LW PD ++++ + D + R+ NG+ Sbjct: 77 RQRWTDERLVFE-GNKSLSLDGRLVELLWVPDTFIVDSKKSFLHDITVENRLIRIFPNGT 135 Query: 443 VSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDF 571 V + R+ + +M L +P D QTCT + S +N +++ F Sbjct: 136 VLYALRITTTVACNMDLTKYPMDKQTCTLQLESWGYNINDVMF 178 >UniRef50_Q95Y52 Cluster: Putative uncharacterized protein; n=2; Caenorhabditis|Rep: Putative uncharacterized protein - Caenorhabditis elegans Length = 508 Score = 47.2 bits (107), Expect = 5e-04 Identities = 39/184 (21%), Positives = 85/184 (46%), Gaps = 11/184 (5%) Frame = +2 Query: 113 ENATSLSLMIDSLLATYDRESPPDSKIVVNLTLHLRH-ANIRESESTVRILADLQMNWID 289 +N + S ++ ++++ Y+R P ++ V + + ++ I + S ++ + W D Sbjct: 61 KNCANDSFILGTIMSNYNRHKIPGGQVDVEVEVWVQEITTISDITSDFQLDIYIYETWYD 120 Query: 290 KRLSWS---AGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYA---LRARVSNNGSVSW 451 L+++ ++ S V E+LW P+ +N+ + + NG+V Sbjct: 121 PALNYAFMNPCKYNLSLNSVLLEKLWTPNSCFINSKTADIHKSPFPNIFLMIYANGTVWT 180 Query: 452 IKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDE--MDFVID--KRIYSMFESXAWD 619 RL + P M L +P D TC+ F S +N+DE MD+ ++ +++ E ++ Sbjct: 181 NYRLKLQGPCIMDLTKFPFDNVTCSLTFESFNYNTDEVKMDWSVNGVQKMRDKMELADYE 240 Query: 620 VTDL 631 + D+ Sbjct: 241 LVDI 244 >UniRef50_A7S2G2 Cluster: Predicted protein; n=2; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 270 Score = 47.2 bits (107), Expect = 5e-04 Identities = 32/133 (24%), Positives = 62/133 (46%), Gaps = 10/133 (7%) Frame = +2 Query: 197 VNLTLHLRHANI---RESESTVRILADLQMNWIDKRLSWSA----GEWGCSTWLVSSERL 355 VN+T+++R ++ RE + + W D RL+++ G+ L +++ + Sbjct: 4 VNITVNMRINSVFDVREEAMDYTMRFAFRQKWRDPRLTYNISLTRGQGHPYIQLETADLI 63 Query: 356 WRPDVVLLNAAATTAGDYA---LRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCT 526 W PD +NA + D L R+ +GS+ +++ ++ M L +P D Q C Sbjct: 64 WYPDTFFMNARKSYIHDVTKKNLGIRLFPDGSIYMSQKITVTAECQMDLRKFPMDTQVCV 123 Query: 527 FKFGSRMHNSDEM 565 +F S H + E+ Sbjct: 124 LQFESFFHTAAEI 136 >UniRef50_A7RLM5 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 317 Score = 47.2 bits (107), Expect = 5e-04 Identities = 27/105 (25%), Positives = 50/105 (47%), Gaps = 5/105 (4%) Frame = +2 Query: 269 LQMNWIDKRLSWSAGEWGCSTWL-VSSERLWRPDVVLLNAAA----TTAGDYALRARVSN 433 L+M W D L W+ ++G T + + + +W P V++ N A + R V + Sbjct: 58 LRMGWKDAFLQWNPADYGGVTQINLEASDIWTPPVIIYNQAGDLGESITSSNTPRPVVRS 117 Query: 434 NGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 568 +G+V W+ I + + + +P D Q C FGS ++ ++D Sbjct: 118 DGTVLWMVPTVIKSSCVIDVKYFPFDQQLCKIIFGSWHYDVSKLD 162 >UniRef50_P45963 Cluster: Acetylcholine receptor subunit alpha-type acr-7 precursor; n=2; Caenorhabditis|Rep: Acetylcholine receptor subunit alpha-type acr-7 precursor - Caenorhabditis elegans Length = 538 Score = 47.2 bits (107), Expect = 5e-04 Identities = 31/142 (21%), Positives = 63/142 (44%), Gaps = 8/142 (5%) Frame = +2 Query: 179 PDSKIVVNLTLHLRHANIRESE-STVRILADLQMNWIDKRLSWSAGEWG--CSTWLVSSE 349 P + V + + ++ + +++ + + A L+ W D RL W+ ++ S + Sbjct: 52 PKKALTVTMKVFIQQVLLVDAKHQMIEVNAWLKYIWTDFRLRWNPLDYENITSVRFQGED 111 Query: 350 RLWRPDVVLLNAAATTAGD-----YALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDM 514 ++W+PD++L N + Y A ++G ++WI M + +P D Sbjct: 112 QIWQPDILLYNRYIEDEQESFDITYKTNAVAYSDGVINWIPPGIFKLSCKMDITLFPFDE 171 Query: 515 QTCTFKFGSRMHNSDEMDFVID 580 Q C KFGS ++ +D +D Sbjct: 172 QICFMKFGSWTYHGFALDLRLD 193 >UniRef50_P46098 Cluster: 5-hydroxytryptamine receptor 3 precursor; n=50; Tetrapoda|Rep: 5-hydroxytryptamine receptor 3 precursor - Homo sapiens (Human) Length = 478 Score = 47.2 bits (107), Expect = 5e-04 Identities = 25/115 (21%), Positives = 51/115 (44%), Gaps = 1/115 (0%) Frame = +2 Query: 227 NIRESESTVRILADLQMNWIDKRLSWSAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAG 403 N+ E + + W D+ L W+ ++ T L + ++ +W PD+++ Sbjct: 72 NVDEKNQVLTTYIWYRQYWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKS 131 Query: 404 DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 568 + + G V K L + T S+ + N+P D+Q C+ F S +H +++ Sbjct: 132 PNIPYVYIRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLHTIQDIN 186 >UniRef50_Q4RLA7 Cluster: Chromosome 21 SCAF15022, whole genome shotgun sequence; n=5; Clupeocephala|Rep: Chromosome 21 SCAF15022, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 592 Score = 46.8 bits (106), Expect = 6e-04 Identities = 28/121 (23%), Positives = 57/121 (47%), Gaps = 3/121 (2%) Frame = +2 Query: 269 LQMNWIDKRLSWSAGEW-GCSTWLVSSERLWRPDVVLLNAAATT-AGDYALRARVSNNGS 442 L+M+W D L W+ E G +++++W PD++L N+A + V+++G Sbjct: 96 LRMSWFDHYLQWNQSEHPGVKNLRFTTDQIWTPDILLYNSADDDFDSTFKTNVLVNSSGY 155 Query: 443 VSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDKR-IYSMFESXAWD 619 + + ++ + +P D+Q C KFGS ++ +D ++ I + WD Sbjct: 156 AEYQPPGIFMSTCNVDVRWFPFDIQRCELKFGSWTYDGWLLDLQMNNADISGYMPNGEWD 215 Query: 620 V 622 + Sbjct: 216 L 216 >UniRef50_Q20828 Cluster: Putative uncharacterized protein; n=2; Caenorhabditis|Rep: Putative uncharacterized protein - Caenorhabditis elegans Length = 517 Score = 46.8 bits (106), Expect = 6e-04 Identities = 41/173 (23%), Positives = 80/173 (46%), Gaps = 11/173 (6%) Frame = +2 Query: 83 TCAIASAAEC--ENATSLSLMIDSLLATYDR-ESPPDSKIVVNLTLHLRHAN-IRESEST 250 T A+A+ E E TS +I+ LL Y +P +S ++V + + ++ N + E S Sbjct: 49 TNAVAATDEDGEELCTSDKTIIEKLLNNYKSFRTPSESGVIVWIEVWVQEVNSVNEITSD 108 Query: 251 VRILADLQMNWIDKRLSW---SAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR- 418 + + W+D L + + ++ S +++W+P+ V +N+ + + Sbjct: 109 FDMDIYVTELWMDSALRYEHLNPCKYNLSLNSEILDQIWKPNTVFINSKSANIHKSPFKN 168 Query: 419 --ARVSNNGSVSWIK-RLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 568 + NG+V W+ R+ + P SM +P D Q+C S +N+ E+D Sbjct: 169 VFLMIYPNGTV-WVNYRVQVKGPCSMDFSAFPMDQQSCHLTLESFSYNNQEVD 220 >UniRef50_Q9UN88 Cluster: Gamma-aminobutyric acid receptor subunit theta precursor (GABA(A) receptor subunit theta); n=18; Tetrapoda|Rep: Gamma-aminobutyric acid receptor subunit theta precursor (GABA(A) receptor subunit theta) - Homo sapiens (Human) Length = 632 Score = 46.8 bits (106), Expect = 6e-04 Identities = 35/145 (24%), Positives = 60/145 (41%), Gaps = 7/145 (4%) Frame = +2 Query: 110 CENATSLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESESTVRILADLQM 277 C N + ++D +L+ YD P+ + + V +++++ I E I Sbjct: 53 CANEAVVQKILDRVLSRYDVRLRPNFGGAPVPVRISIYVTSIEQISEMNMDYTITMFFHQ 112 Query: 278 NWIDKRLSWSAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSN---NGSVS 448 W D RL++ + E+LW PD LN+ D + RV +G+V Sbjct: 113 TWKDSRLAYYETTLNLTLDYRMHEKLWVPDCYFLNSKDAFVHDVTVENRVFQLHPDGTVR 172 Query: 449 WIKRLDISTPISMQLDNWPNDMQTC 523 + RL + S+ L +P D Q C Sbjct: 173 YGIRLTTTAACSLDLHKFPMDKQAC 197 >UniRef50_O00591 Cluster: Gamma-aminobutyric acid receptor subunit pi precursor (GABA(A) receptor subunit pi); n=19; Euteleostomi|Rep: Gamma-aminobutyric acid receptor subunit pi precursor (GABA(A) receptor subunit pi) - Homo sapiens (Human) Length = 440 Score = 46.8 bits (106), Expect = 6e-04 Identities = 40/164 (24%), Positives = 78/164 (47%), Gaps = 9/164 (5%) Frame = +2 Query: 107 ECENATSLSLM-IDSLLATYDRESPPD---SKIVVNLTLHLRH-ANIRESESTVRILADL 271 E + LSL ++L A Y++ P+ + + LTL + ++I ES L Sbjct: 29 EVGRSDKLSLPGFENLTAGYNKFLRPNFGGEPVQIALTLDIASISSISESNMDYTATIYL 88 Query: 272 QMNWIDKRLSWSAGE-WGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNG 439 + W+D+RL + + + LV E LW PD ++ + + + + R+ +NG Sbjct: 89 RQRWMDQRLVFEGNKSFTLDARLV--EFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNG 146 Query: 440 SVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDF 571 +V + R+ + +M L +P D QTC + S ++ ++++F Sbjct: 147 TVLYALRITTTVACNMDLSKYPMDTQTCKLQLESWGYDGNDVEF 190 >UniRef50_UPI0000F1DA85 Cluster: PREDICTED: similar to MGC52789 protein; n=1; Danio rerio|Rep: PREDICTED: similar to MGC52789 protein - Danio rerio Length = 433 Score = 46.4 bits (105), Expect = 9e-04 Identities = 27/114 (23%), Positives = 50/114 (43%), Gaps = 2/114 (1%) Frame = +2 Query: 230 IRESESTVRILADLQMNWIDKRLSWSAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGD 406 + E ++ L W + +W ++ G S V + +W PD+V+ + T Sbjct: 77 VNEKAQSISTQVLLAHGWGNDFTTWKPDDFCGMSACSVKKDMVWTPDIVIAESIKTEIAT 136 Query: 407 YALR-ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEM 565 R+ + G V L +++ M L +P D Q+CT S +H+SD++ Sbjct: 137 MENAFVRLESRGIVFASNTLAVTSACKMDLHLFPFDTQSCTLTIMSSVHSSDQL 190 >UniRef50_UPI0000EB6CC4 Cluster: glycine receptor, beta b; n=1; Danio rerio|Rep: glycine receptor, beta b - Danio rerio Length = 451 Score = 46.0 bits (104), Expect = 0.001 Identities = 40/163 (24%), Positives = 72/163 (44%), Gaps = 11/163 (6%) Frame = +2 Query: 119 ATSLSLMIDSLLATYDRESPPDSKIV-----VNLTLHLRHANIRESESTVRILADLQMNW 283 A S S +++ LL TYD P+ K + VN+ ++ +I+E+ R+ L+ W Sbjct: 61 ANSTSNILNKLLITYDPRIRPNFKGIPVEDRVNIFIN-SFGSIQETTMDYRVNIFLRQRW 119 Query: 284 IDKRLSWSAGEWGCSTWLVSSER---LWRPDVVLLNAAATTAGDYA---LRARVSNNGSV 445 D RL ++ + V + LW+PD+ N + D + + NG V Sbjct: 120 NDPRLRLPQ-DFKSDSLTVDPKMFKCLWKPDLFFANEKSANFHDVTQENILLFIFRNGDV 178 Query: 446 SWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFV 574 RL ++ + L +P D Q C + S + +D++ F+ Sbjct: 179 LISMRLSVTLSCPLDLTLFPMDTQRCKMQLESFGYTTDDLQFM 221 >UniRef50_UPI000065F0EC Cluster: Homolog of Homo sapiens "5-hydroxytryptamine receptor 3 subunit C; n=2; Takifugu rubripes|Rep: Homolog of Homo sapiens "5-hydroxytryptamine receptor 3 subunit C - Takifugu rubripes Length = 411 Score = 46.0 bits (104), Expect = 0.001 Identities = 34/140 (24%), Positives = 58/140 (41%), Gaps = 10/140 (7%) Frame = +2 Query: 251 VRILADLQMNWIDKRLSWSAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVS 430 + ++ L + W LSW E G V E +W PDV + + Sbjct: 45 ITVVGVLGVEWDIDGLSWDVQECGTEKVSVLRESIWVPDVHIAEFMEEDQSPRTPFVYLY 104 Query: 431 NNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEM---------DFVIDK 583 N G V + + + + + + +P D+Q CT FGS +H + E+ D + + Sbjct: 105 NTGGVFDDRPIRVVSSCKLDIYTFPFDIQNCTLTFGSYVHFASEIRMSQGSTAEDILQES 164 Query: 584 RIYSMFESXA-WDVTDLSXA 640 R +FE+ WD+ D+ A Sbjct: 165 R--EVFETNGEWDLADIEIA 182 >UniRef50_UPI0000660F16 Cluster: Homolog of Homo sapiens "Splice Isoform 2 of 5-hydroxytryptamine 3 receptor precursor; n=1; Takifugu rubripes|Rep: Homolog of Homo sapiens "Splice Isoform 2 of 5-hydroxytryptamine 3 receptor precursor - Takifugu rubripes Length = 430 Score = 45.6 bits (103), Expect = 0.002 Identities = 26/99 (26%), Positives = 40/99 (40%) Frame = +2 Query: 269 LQMNWIDKRLSWSAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVS 448 L W LSW E G V E +W PDV + + N G V Sbjct: 7 LMQEWDIDGLSWDVQECGTEKVSVLRESIWVPDVHIAEFMEENKSQRTPFVYLYNTGGVF 66 Query: 449 WIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEM 565 + + + + + + +P D+Q CT FGS +H + E+ Sbjct: 67 DDRPIRVVSSCKLDIYTFPFDIQNCTLTFGSYVHFASEI 105 >UniRef50_Q4S0E0 Cluster: Chromosome 2 SCAF14781, whole genome shotgun sequence; n=5; Euteleostomi|Rep: Chromosome 2 SCAF14781, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 525 Score = 45.6 bits (103), Expect = 0.002 Identities = 35/126 (27%), Positives = 56/126 (44%), Gaps = 5/126 (3%) Frame = +2 Query: 179 PDSKIVVNLTLHLRHANIRESESTVRILADLQMNWIDKRLSWSAGEWGCSTWLVSS--ER 352 P + N+ ++ +I E+ R+ L+ W D RL++S S L S + Sbjct: 113 PPVNVTCNIFIN-SFGSIAETTMDYRVNIFLRQKWNDPRLAYSKYP-DPSLDLDPSMLDS 170 Query: 353 LWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTC 523 +W+PD+ N D R+ NG+V + RL + M L N+P D+QTC Sbjct: 171 IWKPDLFFANEKGANFHDVTTDNKLLRIFKNGNVLYSIRLTLILSCPMDLKNFPMDVQTC 230 Query: 524 TFKFGS 541 T + S Sbjct: 231 TMQLES 236 >UniRef50_Q7NDN8 Cluster: Glr4197 protein; n=1; Gloeobacter violaceus|Rep: Glr4197 protein - Gloeobacter violaceus Length = 359 Score = 45.6 bits (103), Expect = 0.002 Identities = 30/124 (24%), Positives = 55/124 (44%), Gaps = 5/124 (4%) Frame = +2 Query: 164 DRESPP----DSKIVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWSAGEWGCS 328 D SPP D + VN ++L ++ + T ++ A L ++W D+RL++ G Sbjct: 45 DMVSPPPPIADEPLTVNTGIYLIECYSLDDKAETFKVNAFLSLSWKDRRLAFDPVRSGVR 104 Query: 329 TWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPN 508 E +W P++ +N D + VS +G+V +++R + +P Sbjct: 105 VKTYEPEAIWIPEIRFVNVENARDAD-VVDISVSPDGTVQYLERFSARVLSPLDFRRYPF 163 Query: 509 DMQT 520 D QT Sbjct: 164 DSQT 167 >UniRef50_Q8TA51 Cluster: Putative uncharacterized protein; n=3; Caenorhabditis|Rep: Putative uncharacterized protein - Caenorhabditis elegans Length = 428 Score = 45.6 bits (103), Expect = 0.002 Identities = 27/98 (27%), Positives = 46/98 (46%), Gaps = 4/98 (4%) Frame = +2 Query: 269 LQMNWIDKRLSWSAGEWGCSTW-LVSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 442 L+++W D+RL W+ EW L S RLW PD+ + + D+ + +N + Sbjct: 107 LKLSWKDRRLRWNPEEWKTEVLRLKSMGRLWSPDINSDKLQTGSQSTDFVNYHDIQSNYN 166 Query: 443 VSWIKRLDISTPISMQLD--NWPNDMQTCTFKFGSRMH 550 + RL+ Q+D +PND + C F S ++ Sbjct: 167 GNVTARLEFRMKAQCQIDYTEYPNDRKHCCFNLQSNLY 204 >UniRef50_A7RTF8 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 262 Score = 45.6 bits (103), Expect = 0.002 Identities = 19/73 (26%), Positives = 38/73 (52%) Frame = +2 Query: 347 ERLWRPDVVLLNAAATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCT 526 +++W+PD + N ++T + + G V + +R+ + M L N+P D Q+C+ Sbjct: 35 KQIWKPDTYINNEKSSTVPENQFLLTIDPEGRVVYSQRMTVVASCMMYLRNYPMDTQSCS 94 Query: 527 FKFGSRMHNSDEM 565 F S N+D++ Sbjct: 95 ISFESYGMNNDDL 107 >UniRef50_A7T7Z5 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 152 Score = 45.2 bits (102), Expect = 0.002 Identities = 35/136 (25%), Positives = 59/136 (43%), Gaps = 10/136 (7%) Frame = +2 Query: 161 YDRESPP----DSKIVVNLTLHL-RHANIRESESTVRILADLQMNWIDKRLSWSAGEWGC 325 YD+E P ++ V L L + ++ VR+ NW D L+W ++G Sbjct: 17 YDKEVRPVMNNHEQLKVYFALKLVQIVDVDGKSEAVRVNVWTTQNWKDPFLTWDPSDYGG 76 Query: 326 STWL-VSSERLWRPDVVLLNAAATT-AGD---YALRARVSNNGSVSWIKRLDISTPISMQ 490 + V+ +W P ++L N AA AG Y + +++NG+V+W + Sbjct: 77 IEEINVTPTMVWLPIIILYNNAANGFAGGPEKYKTKVVINSNGTVNWFAATQFLFSCKIN 136 Query: 491 LDNWPNDMQTCTFKFG 538 + +P D Q C FG Sbjct: 137 IRWFPFDEQYCYMTFG 152 >UniRef50_A7SDE9 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 299 Score = 45.2 bits (102), Expect = 0.002 Identities = 36/124 (29%), Positives = 57/124 (45%), Gaps = 7/124 (5%) Frame = +2 Query: 191 IVVNLTLHLRH-ANIRESESTVRILADLQMNWIDKRLSWSAGEWGCSTWLVSSE--RLWR 361 +VV+L++++ NI E+ + + W D+RL A S L E R+WR Sbjct: 4 VVVDLSIYVSSFGNIEEANMEYKFFGYFRQFWKDERL---ANRVNHSVILKGDEISRMWR 60 Query: 362 PDVVLLNA--AATTAGDYALRARVS--NNGSVSWIKRLDISTPISMQLDNWPNDMQTCTF 529 PD NA ++ T D + + V+ NG V + + I+ + L +P D Q C Sbjct: 61 PDPFCYNARKSSLTDADADINSMVTIHPNGDVVYSRMTIITAECELNLHKFPMDEQKCHL 120 Query: 530 KFGS 541 K GS Sbjct: 121 KIGS 124 >UniRef50_UPI0000F1E62D Cluster: PREDICTED: hypothetical protein; n=1; Danio rerio|Rep: PREDICTED: hypothetical protein - Danio rerio Length = 357 Score = 44.8 bits (101), Expect = 0.003 Identities = 25/91 (27%), Positives = 39/91 (42%) Frame = +2 Query: 269 LQMNWIDKRLSWSAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVS 448 L + W + LSW E G + ++LW PD+V+ V +NG V Sbjct: 63 LDVFWNIEGLSWDPEECGTDRISLPRKQLWMPDIVINEFMDENKAPVTYYLYVQHNGMVM 122 Query: 449 WIKRLDISTPISMQLDNWPNDMQTCTFKFGS 541 + + + M + +P D+Q CTF F S Sbjct: 123 DDRPTHVISSCIMDIYTFPFDIQNCTFTFNS 153 >UniRef50_UPI0000E49D12 Cluster: PREDICTED: similar to acetylcholin receptor alpha subunit 1A; n=2; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to acetylcholin receptor alpha subunit 1A - Strongylocentrotus purpuratus Length = 462 Score = 44.8 bits (101), Expect = 0.003 Identities = 33/143 (23%), Positives = 62/143 (43%), Gaps = 8/143 (5%) Frame = +2 Query: 236 ESESTVRILADLQMNWIDKRLSWSAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYA 412 E + + ++++M W D+ L W EW G ++ + +W+PD L A Sbjct: 85 EHSQHITLRSNMKMTWRDEYLQWDPSEWDGITSVTLRPSDIWKPDFDLEQNVERVHFIVA 144 Query: 413 LRARVSN-NGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKF------GSRMHNSDEMDF 571 +++ G+V WI + +T + + +P D+Q C F S+M E D Sbjct: 145 DTYVIADYTGTVRWIFPVITTTACKINIVYFPYDVQQCNVTFYPWTLDNSQMRLLAEDDD 204 Query: 572 VIDKRIYSMFESXAWDVTDLSXA 640 +++Y + WD+T+ A Sbjct: 205 DAHQQMY--IRNGVWDLTNFQAA 225 >UniRef50_UPI000058727F Cluster: PREDICTED: similar to Chain B, Refined Structure Of The Nicotinic Acetylcholine Receptor At 4a Resolution.; n=2; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to Chain B, Refined Structure Of The Nicotinic Acetylcholine Receptor At 4a Resolution. - Strongylocentrotus purpuratus Length = 449 Score = 44.8 bits (101), Expect = 0.003 Identities = 33/116 (28%), Positives = 57/116 (49%), Gaps = 5/116 (4%) Frame = +2 Query: 191 IVVNLTLHLRHANIRESESTVRILADLQMNWIDKRLSWSAGEWGCSTWLVSSERL-WRPD 367 + V+LTL ++ E + + + + + W D+RL+W +G +G T L RL W P Sbjct: 61 VTVHLTLQ-SVKDVNEKKQGMVGTSTITVVWRDERLTWMSGHYGNITVLTLPCRLVWTPS 119 Query: 368 VVLLNAAATTA----GDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTC 523 + L N+ + + ++ + N+G V+ L ST +M L +P D QTC Sbjct: 120 IRLGNSNSEDSRILKNPEDIKVFIKNDGQVTLETNLLHSTACAMNLALFPFDTQTC 175 >UniRef50_UPI00006A0062 Cluster: UPI00006A0062 related cluster; n=1; Xenopus tropicalis|Rep: UPI00006A0062 UniRef100 entry - Xenopus tropicalis Length = 457 Score = 44.8 bits (101), Expect = 0.003 Identities = 28/104 (26%), Positives = 50/104 (48%), Gaps = 2/104 (1%) Frame = +2 Query: 260 LADLQMNWIDKRLSWSAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALR-ARVSN 433 +A + +W + ++W + + G +VS +WRPD+ + + ++ Sbjct: 77 VACITQSWKNDFVNWDSNTYCGIEKVVVSDTLVWRPDLYIYEMVDDDDKSPKINYLKIYY 136 Query: 434 NGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEM 565 NG V+ K L I+ SMQ +P D Q C+ FGS ++N E+ Sbjct: 137 NGIVTNSKPLRIAGSCSMQNFKFPFDEQNCSLTFGSYVYNDFEV 180 >UniRef50_A7SVS1 Cluster: Predicted protein; n=5; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 318 Score = 44.8 bits (101), Expect = 0.003 Identities = 39/165 (23%), Positives = 72/165 (43%), Gaps = 8/165 (4%) Frame = +2 Query: 125 SLSLMIDSLLATYDRESPPDSKI-VVNLTLHLRHANIRE-SESTVRILADLQMN--WIDK 292 ++S ++D + YD+ P I V++ L + + E SE+ + D+ + W + Sbjct: 1 NISKLLDDVFKRYDKRIRPYYGIKAVDIQLDMLILSFGELSETNMEFTVDMYLGQFWKEP 60 Query: 293 RLSWSAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVS----NNGSVSWIKR 460 RL++ + V+SE+LW PD +N+ T + +GSV R Sbjct: 61 RLAFGIKREIILSG-VASEKLWVPDTFFVNSIDTKVHALLFSNKKVWINLTDGSVMLSAR 119 Query: 461 LDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDKRIYS 595 L + L N+P D QTC F S + ++++ ++ S Sbjct: 120 LTTRNSCKVDLRNYPMDEQTCHLPFESFSYEQKDLNYTWRSKVGS 164 >UniRef50_A7S8Q4 Cluster: Predicted protein; n=3; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 311 Score = 44.8 bits (101), Expect = 0.003 Identities = 29/121 (23%), Positives = 57/121 (47%), Gaps = 7/121 (5%) Frame = +2 Query: 227 NIRESESTVRILADLQMNWIDKRLSWSAGEWGCSTWL-VSSERLWRPDVVL---LNAAAT 394 ++ + + + ++ W + L+W +G L VS++ +W PD++L ++ Sbjct: 34 DVNAKQQAITVYGWVRQMWNNSLLTWDPALFGGLDILHVSAKDVWVPDILLFYNVDEQDQ 93 Query: 395 TAGD---YALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEM 565 TAG Y + +NG+ W + + +++ +P D QTC KFGS H+ + Sbjct: 94 TAGGRTTYKTDVIMYSNGTNKWRSPALLKSICKIKVKFFPFDSQTCKLKFGSFSHDITTL 153 Query: 566 D 568 D Sbjct: 154 D 154 >UniRef50_O75311 Cluster: Glycine receptor subunit alpha-3 precursor; n=128; Euteleostomi|Rep: Glycine receptor subunit alpha-3 precursor - Homo sapiens (Human) Length = 464 Score = 44.8 bits (101), Expect = 0.003 Identities = 37/145 (25%), Positives = 64/145 (44%), Gaps = 8/145 (5%) Frame = +2 Query: 161 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWSAGEWGCS 328 YD P+ K VN+T ++ +I E+ R+ L+ W D RL++S Sbjct: 57 YDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPDDSL 116 Query: 329 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLD 496 S + +W+PD+ N + R+ NG+V + RL ++ M L Sbjct: 117 DLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLK 176 Query: 497 NWPNDMQTCTFKFGSRMHNSDEMDF 571 N+P D+QTC + S + +++ F Sbjct: 177 NFPMDVQTCIMQLESFGYTMNDLIF 201 >UniRef50_O14764 Cluster: Gamma-aminobutyric acid receptor subunit delta precursor (GABA(A) receptor subunit delta); n=27; Euteleostomi|Rep: Gamma-aminobutyric acid receptor subunit delta precursor (GABA(A) receptor subunit delta) - Homo sapiens (Human) Length = 452 Score = 44.8 bits (101), Expect = 0.003 Identities = 37/149 (24%), Positives = 64/149 (42%), Gaps = 7/149 (4%) Frame = +2 Query: 140 IDSLLATYDRESPPD-SKIVVNLTLHLRHANI---RESESTVRILADLQMNWIDKRLSWS 307 +D L+A Y R P VN+ L L A+I E+ + L +W D RLS++ Sbjct: 44 LDGLIAGYARNFRPGIGGPPVNVALALEVASIDHISEANMEYTMTVFLHQSWRDSRLSYN 103 Query: 308 AGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTP 478 ++LW PD ++NA + D + R+ +G + + R+ + Sbjct: 104 HTNETLGLDSRFVDKLWLPDTFIVNAKSAWFHDVTVENKLIRLQPDGVILYSIRITSTVA 163 Query: 479 ISMQLDNWPNDMQTCTFKFGSRMHNSDEM 565 M L +P D Q C S ++S+++ Sbjct: 164 CDMDLAKYPMDEQECMLDLESYGYSSEDI 192 >UniRef50_Q6U4B6 Cluster: Nicotinic acetylcholine receptor alpha 2 subunit; n=2; Nilaparvata lugens|Rep: Nicotinic acetylcholine receptor alpha 2 subunit - Nilaparvata lugens (Brown planthopper) Length = 590 Score = 44.4 bits (100), Expect = 0.003 Identities = 30/89 (33%), Positives = 42/89 (47%), Gaps = 5/89 (5%) Frame = +2 Query: 311 GEWGCSTWL-VSSERLWRPDVVLLNAA----ATTAGDYALRARVSNNGSVSWIKRLDIST 475 G G ST L V SE +W PD+VL N A A A +A + G V W + Sbjct: 117 GGVGSSTELAVPSEHIWDPDIVLYNNADGKYAVGGSMTATKAYLHYGGGVWWSPPAIYGS 176 Query: 476 PISMQLDNWPNDMQTCTFKFGSRMHNSDE 562 + ++ +P D Q C KFGS ++ D+ Sbjct: 177 SCEIDVEYFPFDEQGCYMKFGSWTYDGDQ 205 >UniRef50_Q22085 Cluster: Putative uncharacterized protein lgc-17; n=12; Caenorhabditis|Rep: Putative uncharacterized protein lgc-17 - Caenorhabditis elegans Length = 401 Score = 44.4 bits (100), Expect = 0.003 Identities = 34/157 (21%), Positives = 65/157 (41%), Gaps = 10/157 (6%) Frame = +2 Query: 203 LTLHLRHANIRESESTVRILADLQMNWIDKRLSWSAGEW-GCSTWLVSSERLWRPDVVLL 379 L +L+ ++E E V ++ +L W D RLSW++ + T V E++W P + Sbjct: 79 LLYYLKLVEVQEPEEKVSVVLELVEQWYDPRLSWNSSLYSNIPTVFVRQEKVWSPTLSAF 138 Query: 380 NA-AATTAGDYALR-ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHN 553 D R + + G + + +S+ M + +P D QTC F + N Sbjct: 139 GVNEIIDFRDQDFRIVSIDDIGYIQDYLSVRVSSNCPMDVSRFPFDSQTCQICFCLPIFN 198 Query: 554 -------SDEMDFVIDKRIYSMFESXAWDVTDLSXAV 643 ++ + ++ ++I + W V L+ V Sbjct: 199 IRQVKILNEIYEGILQEKIIKTMGNSEWKVVSLTNRV 235 >UniRef50_A4FTX5 Cluster: CHRNB4 protein; n=1; Homo sapiens|Rep: CHRNB4 protein - Homo sapiens (Human) Length = 198 Score = 44.4 bits (100), Expect = 0.003 Identities = 29/115 (25%), Positives = 54/115 (46%), Gaps = 8/115 (6%) Frame = +2 Query: 89 AIASAAECENATSLSLMIDSLL--ATYDRESPP--DSKIVVNLTLHLRHA---NIRESES 247 A+ C A + ++D LL Y+ P S ++++ L L A ++ E E Sbjct: 14 ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQ 73 Query: 248 TVRILADLQMNWIDKRLSWSAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDY 409 + L+ W D RL+W++ + G + + ++R+W PD+VL N + T + Sbjct: 74 IMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNKSLRTGSTW 128 >UniRef50_UPI0000E45D33 Cluster: PREDICTED: similar to nicotinic acetylcholine receptor subunit alpha 6; n=2; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to nicotinic acetylcholine receptor subunit alpha 6 - Strongylocentrotus purpuratus Length = 440 Score = 44.0 bits (99), Expect = 0.005 Identities = 25/104 (24%), Positives = 47/104 (45%), Gaps = 4/104 (3%) Frame = +2 Query: 236 ESESTVRILADLQMNWIDKRLSWSAGE-WGCSTWLVSSERLWRPDVVL---LNAAATTAG 403 E+ V + +++++ W D+ L W E G + + ++WRPDVVL L+ + Sbjct: 77 ETHQMVTVRSNMRLQWTDEYLQWDPDENGGIYNITLKTNQVWRPDVVLDEDLDRDFISIP 136 Query: 404 DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKF 535 + V G++ W+ ++ M + +P D Q C F Sbjct: 137 EADTFVIVQYTGAMDWLFPAITTSACKMNIQYFPFDTQQCVLTF 180 >UniRef50_Q7ZTN5 Cluster: MGC52789 protein; n=1; Xenopus laevis|Rep: MGC52789 protein - Xenopus laevis (African clawed frog) Length = 459 Score = 44.0 bits (99), Expect = 0.005 Identities = 30/124 (24%), Positives = 56/124 (45%), Gaps = 2/124 (1%) Frame = +2 Query: 185 SKIVVNLTLHLRHANIRESESTVRILADLQMNWIDKRLSWSAGEW-GCSTWLVSSERLWR 361 S I +++TL+ A + S T+ L + W ++ +SW+ + + E LW+ Sbjct: 53 SHIYIDITLYTI-AKLDTSTQTLTSFVWLTLEWTNEYISWNPNNFCDMKEFNTLGESLWK 111 Query: 362 PDVVLLNAAATTAGDYALRA-RVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFG 538 PD+ + + V +G V+ K L I + + + +P D QTC+ FG Sbjct: 112 PDLYIYQITEVDDKSPVIPYFTVHYDGKVTLDKPLRILSSCDVNIYKFPFDTQTCSLTFG 171 Query: 539 SRMH 550 S ++ Sbjct: 172 SYIY 175 >UniRef50_Q4BXY7 Cluster: Neurotransmitter-gated ion-channel ligand-binding; n=2; Chroococcales|Rep: Neurotransmitter-gated ion-channel ligand-binding - Crocosphaera watsonii Length = 340 Score = 44.0 bits (99), Expect = 0.005 Identities = 35/136 (25%), Positives = 63/136 (46%), Gaps = 1/136 (0%) Frame = +2 Query: 170 ESPPDSKIVVNL-TLHLRHANIRESESTVRILADLQMNWIDKRLSWSAGEWGCSTWLVSS 346 + P ++I+V + TL L A I E E TV I L + W D R + S + Sbjct: 34 DDPEITQILVGIYTLDL--AKINEVEQTVYIDFYLGLQWYDSRFDSALSNTNLSPYQRKL 91 Query: 347 ERLWRPDVVLLNAAATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCT 526 E +W+P++ ++N + +++ G V++ +R S+ L +P D QT Sbjct: 92 EEVWQPNLHIIN-QRNLDKELDEIVHINSQGIVTYRQRYYGKLATSLDLRRFPFDEQTIK 150 Query: 527 FKFGSRMHNSDEMDFV 574 + S ++ +E+ FV Sbjct: 151 IELISFSYSPEEIHFV 166 >UniRef50_Q61I41 Cluster: Putative uncharacterized protein CBG10413; n=1; Caenorhabditis briggsae|Rep: Putative uncharacterized protein CBG10413 - Caenorhabditis briggsae Length = 366 Score = 44.0 bits (99), Expect = 0.005 Identities = 31/133 (23%), Positives = 59/133 (44%), Gaps = 4/133 (3%) Frame = +2 Query: 176 PPDSKIVVNLTLHLRHANIRESESTVRILADLQMNWIDKRLSWSAGEW-GCSTWLVSSER 352 PP +++ + + + L+ ++ E E L D W D RL+W+ E+ G S V + Sbjct: 69 PPMTELNLIMAM-LKLVDVVEVEEKATFLFDYSAEWTDHRLTWNPLEYGGISHIYVPQKS 127 Query: 353 LWRPDVVLLNAAAT---TAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTC 523 +W P++ + +A + D A ++ NG+V + S M + +P D C Sbjct: 128 IWLPEITIADAHEVKFFESEDAPSIAWINFNGTVGFYTSTVASVICEMDVFQFPMDQHEC 187 Query: 524 TFKFGSRMHNSDE 562 + + +DE Sbjct: 188 GVSVVANTYFADE 200 >UniRef50_Q2WF65 Cluster: Gaba/glycine receptor family (See gbr) protein 2, isoform a; n=3; Caenorhabditis|Rep: Gaba/glycine receptor family (See gbr) protein 2, isoform a - Caenorhabditis elegans Length = 546 Score = 44.0 bits (99), Expect = 0.005 Identities = 34/166 (20%), Positives = 69/166 (41%), Gaps = 13/166 (7%) Frame = +2 Query: 107 ECENATSLSLMIDSLL----ATYDRESPP-----DSKIVVNLTLHLRH-ANIRESESTVR 256 E + + + +D+LL YD +SPP + VV L +++ ++ R + Sbjct: 19 EASRSEPVPIYLDNLLNAGRQVYDNQSPPVQHDKEEVTVVELAMYIEGMSSFRTQTMDFQ 78 Query: 257 ILADLQMNWIDKRLSWSAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYA---LRARV 427 + Q W D RL+ + ++W+PDV NA + + Sbjct: 79 LDVYFQQFWRDPRLAHNETRRVLVKDKAVLHKMWKPDVYFANARIAEFHEVTQPNFLVWI 138 Query: 428 SNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEM 565 +GS+ + R+ + ++ L+ WP D Q C + S + ++++ Sbjct: 139 QPDGSILYDTRISMVVVCTLNLEKWPLDSQRCHLRILSYAYTTEQL 184 >UniRef50_UPI00015B60A2 Cluster: PREDICTED: similar to nicotinic acetylcholine receptor alpha6 subunit; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to nicotinic acetylcholine receptor alpha6 subunit - Nasonia vitripennis Length = 724 Score = 43.6 bits (98), Expect = 0.006 Identities = 29/113 (25%), Positives = 59/113 (52%), Gaps = 7/113 (6%) Frame = +2 Query: 137 MIDSLLATYDR-ESPPDSK---IVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLS 301 +++ LL+ Y+ E P +++ + V + L+ ++ E + A L++ W D L Sbjct: 73 LLNKLLSNYNTLERPVENESEPLQVKFGITLQQIIDVDEKNQILTTNAWLKLEWTDYNLQ 132 Query: 302 WSAGEWGCSTWL-VSSERLWRPDVVLLNAAAT-TAGDYALRARVSNNGSVSWI 454 W+ E+G L ++ +LW+PDV++ N+A G + V++NGS ++ Sbjct: 133 WNESEFGGVKDLRITPSKLWKPDVLMYNSAEEGFDGTFQTNVVVTHNGSCLYV 185 >UniRef50_Q4SRT2 Cluster: Chromosome undetermined SCAF14492, whole genome shotgun sequence; n=6; Euteleostomi|Rep: Chromosome undetermined SCAF14492, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 445 Score = 43.6 bits (98), Expect = 0.006 Identities = 25/100 (25%), Positives = 45/100 (45%), Gaps = 1/100 (1%) Frame = +2 Query: 281 WIDKRLSWSAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVSWIK 457 W D+ L W E+ G S + SE +W PDV++ V+ +G V + Sbjct: 74 WTDEFLVWDPEEFDGLSEISLPSEAVWIPDVIVTEFVDAGKAPPIPYVYVNASGWVRSYR 133 Query: 458 RLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVI 577 + + S+++ +P D C+ F S +H+ E+D + Sbjct: 134 PMQVVLACSLEMFAFPFDKHNCSLSFRSWLHSVKEIDLAL 173 >UniRef50_A2BGE6 Cluster: Glycine receptor, alpha 4b; n=5; Danio rerio|Rep: Glycine receptor, alpha 4b - Danio rerio (Zebrafish) (Brachydanio rerio) Length = 536 Score = 43.6 bits (98), Expect = 0.006 Identities = 37/145 (25%), Positives = 62/145 (42%), Gaps = 8/145 (5%) Frame = +2 Query: 161 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWSAGEWGCS 328 YD P+ K VN+T ++ +I E+ R+ L+ W D RL++ Sbjct: 101 YDARIRPNFKGPPVNVTCNIFINSFGSITETTMDYRLNVFLRQQWNDPRLAYKEYPDDSL 160 Query: 329 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLD 496 S + +W+PD+ N + R+ NG+V + RL + M L Sbjct: 161 DLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFQNGNVLYSIRLTLILSCPMDLK 220 Query: 497 NWPNDMQTCTFKFGSRMHNSDEMDF 571 N+P D QTCT + S + +++ F Sbjct: 221 NFPMDTQTCTMQLESFGYTMNDLIF 245 >UniRef50_Q93323 Cluster: Putative uncharacterized protein lgc-21; n=2; Caenorhabditis|Rep: Putative uncharacterized protein lgc-21 - Caenorhabditis elegans Length = 409 Score = 43.6 bits (98), Expect = 0.006 Identities = 37/148 (25%), Positives = 60/148 (40%), Gaps = 7/148 (4%) Frame = +2 Query: 113 ENATSLS-LMIDSLLATYDRESPPDSKIVVNLT-LHLRHANIRESESTVRILADLQMNWI 286 E+A L+ L I +A+ + +N L+H + E + I L+++W Sbjct: 33 ESAKKLAKLNIPHAIASIPPNYLSQQPVTINFAQFTLQHFELNEHLKDISIHGYLELSWH 92 Query: 287 DKRLSWSAGEWGCSTWLVSS-ERLWRPDVVLLNAAATTAGDYALRAR---VSNNGSVSWI 454 D RL W+ W + +V S +W P + N A R +N G+VS Sbjct: 93 DDRLMWNQDTWKKNKLVVHSFHHIWVPLLGSQNPENHLKNGDAFEIRKVETTNQGNVSAK 152 Query: 455 KRLDISTPI-SMQLDNWPNDMQTCTFKF 535 + T +N+PND+ C F F Sbjct: 153 VAFSLRTFCDDTDFENYPNDVYKCCFSF 180 >UniRef50_Q4W520 Cluster: Putative uncharacterized protein; n=1; Caenorhabditis elegans|Rep: Putative uncharacterized protein - Caenorhabditis elegans Length = 397 Score = 43.6 bits (98), Expect = 0.006 Identities = 29/133 (21%), Positives = 59/133 (44%), Gaps = 12/133 (9%) Frame = +2 Query: 209 LHLRHAN-IRESESTVRILADLQMNWIDKRLSWSAGEW-GCSTWLVSSERLWRP------ 364 LH+ H + I++ + +++ W+D+RL W+ + G T+ + +WR Sbjct: 62 LHVDHIHDIQDEQGVLKMALTFTFTWMDERLMWNPSNYSGIRTFSTTRHEMWRKKFWTPT 121 Query: 365 ----DVVLLNAAATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFK 532 DV + + + +S++G V R+ ++ P ++PND + CTF Sbjct: 122 LMMTDVPNSRRPSDVFKPFDMDIYISSSGMVRTSARMMLTIPCRTGFGSYPNDYKNCTFT 181 Query: 533 FGSRMHNSDEMDF 571 S + +D+ F Sbjct: 182 LMSPYY-ADQFRF 193 >UniRef50_P25123 Cluster: Gamma-aminobutyric acid receptor subunit beta precursor (GABA(A) receptor subunit beta); n=45; Pancrustacea|Rep: Gamma-aminobutyric acid receptor subunit beta precursor (GABA(A) receptor subunit beta) - Drosophila melanogaster (Fruit fly) Length = 606 Score = 43.6 bits (98), Expect = 0.006 Identities = 40/152 (26%), Positives = 70/152 (46%), Gaps = 13/152 (8%) Frame = +2 Query: 125 SLSLMIDSLLATYDRESPPD---SKIVVNLTLH-LRHANIRESESTVRILADLQMNWIDK 292 ++S ++DS +YD+ P+ + V +T++ L +++ E + + W D Sbjct: 58 NISAILDSFSVSYDKRVRPNYGGPPVEVGVTMYVLSISSVSEVLMDFTLDFYFRQFWTDP 117 Query: 293 RLSWSAGEWGCSTWLVSSE---RLWRPDVVLLNAA------ATTAGDYALRARVSNNGSV 445 RL++ G T V SE +W PD +N ATT+ ++ RV ++GS+ Sbjct: 118 RLAYRKRP-GVETLSVGSEFIKNIWVPDTFFVNEKQSYFHIATTSNEFI---RVHHSGSI 173 Query: 446 SWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 541 + RL I+ M L +P D Q C + S Sbjct: 174 TRSIRLTITASCPMNLQYFPMDRQLCHIEIES 205 >UniRef50_UPI0000E4906A Cluster: PREDICTED: similar to nicotinic acetylcholine receptor subunit type G; n=1; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to nicotinic acetylcholine receptor subunit type G - Strongylocentrotus purpuratus Length = 705 Score = 43.2 bits (97), Expect = 0.008 Identities = 23/104 (22%), Positives = 49/104 (47%), Gaps = 2/104 (1%) Frame = +2 Query: 236 ESESTVRILADLQMNWIDKRLSWSAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDY- 409 E++ + I+A ++M+W D+ ++W+ ++ G + LW PD+ L + + Y Sbjct: 35 ETQQQLTIMAYMRMSWRDEFITWNPDDYDGIELLALRPSDLWLPDIALYQSCSKEFISYQ 94 Query: 410 ALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 541 NG+ W +++ + + +P D+Q C FG+ Sbjct: 95 ETYVLCLYNGTCDWHFPAILTSTCKVDVRYFPFDIQLCDLTFGA 138 >UniRef50_Q4RU50 Cluster: Chromosome 1 SCAF14995, whole genome shotgun sequence; n=3; Tetraodontidae|Rep: Chromosome 1 SCAF14995, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 1044 Score = 43.2 bits (97), Expect = 0.008 Identities = 24/90 (26%), Positives = 39/90 (43%) Frame = +2 Query: 281 WIDKRLSWSAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVSWIKR 460 W + LSW A E G + E+LW PD+ + + N G V Sbjct: 11 WDIEGLSWDAEECGTQRVSLPREKLWIPDIHITEFMDEDKSPRTPYVYIYNTGHVFDDSP 70 Query: 461 LDISTPISMQLDNWPNDMQTCTFKFGSRMH 550 L + + + + ++P D+Q C+ FGS +H Sbjct: 71 LRVVSTCKLGIYSFPFDIQNCSLTFGSYIH 100 >UniRef50_O16426 Cluster: Ligand-gated ion channel protein 1; n=2; Caenorhabditis elegans|Rep: Ligand-gated ion channel protein 1 - Caenorhabditis elegans Length = 371 Score = 42.7 bits (96), Expect = 0.011 Identities = 29/120 (24%), Positives = 53/120 (44%), Gaps = 4/120 (3%) Frame = +2 Query: 176 PPDSKIVVNLTLHLRHANIRESESTVRILADLQMNWIDKRLSWSAGEW-GCSTWLVSSER 352 PP +++ + + + L+ ++ E E V L D W D+RL W+ E+ G S V Sbjct: 51 PPITELKLTMAM-LKLVDVVEVEEKVTFLFDYLAEWTDQRLKWNPLEYGGISHIYVPQRM 109 Query: 353 LWRPDVVLLNAAAT---TAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTC 523 +W P+V + +A + D A ++ NG+ + S + + +P D C Sbjct: 110 IWLPEVTIADAHEVKFFESDDAPRTAWINYNGTTGFYTSTVSSVICQLDVYKFPLDRHEC 169 >UniRef50_P34271 Cluster: Acetylcholine receptor-like protein cup-4 precursor; n=3; Caenorhabditis|Rep: Acetylcholine receptor-like protein cup-4 precursor - Caenorhabditis elegans Length = 433 Score = 42.7 bits (96), Expect = 0.011 Identities = 27/131 (20%), Positives = 56/131 (42%), Gaps = 9/131 (6%) Frame = +2 Query: 194 VVNLTLHLRHANIRESESTVRILADLQMNWIDKRLSWSAGEWGCSTWL-VSSERLWRPDV 370 +V++ H+ H +I + E T+ + + M W D+ L W ++ + V ++W+P + Sbjct: 74 IVDVHWHIIHVSINQREQTMTVHGHIYMRWFDEFLVWDPKDFNNIQYARVKKWQVWQPKI 133 Query: 371 VLLNAAA--TTAGDYALRARV------SNNGSVSWIKRLDISTPISMQLDNWPNDMQTCT 526 + N+A+ +A D++ A V + V I + ++P D+ C Sbjct: 134 KVSNSASGLGSAFDFSTSAHVIIQMMGKDRAKVEMYPTFSIKVGCAFDFTDYPYDLNKCA 193 Query: 527 FKFGSRMHNSD 559 S +D Sbjct: 194 INLFSTSTMAD 204 >UniRef50_Q9NA62 Cluster: Putative uncharacterized protein; n=1; Caenorhabditis elegans|Rep: Putative uncharacterized protein - Caenorhabditis elegans Length = 434 Score = 42.3 bits (95), Expect = 0.014 Identities = 37/150 (24%), Positives = 70/150 (46%), Gaps = 10/150 (6%) Frame = +2 Query: 149 LLATYDRESPPDS---KIVVNLTLHLRHANIRESESTVRILADLQMNWIDKRLSWSAGEW 319 L+ Y R + P+ K+ V +T+ ++I T I + W DKRL++S + Sbjct: 63 LMTNYSRNALPEPAPVKVEVEITIQ-DISDISAITGTFTIDYWISAIWNDKRLAFSHLDP 121 Query: 320 GCSTWLVSSE---RLWRPDVVLLNAAATTAGDYA---LRARVSNNGSVSWIK-RLDISTP 478 + + +LW P+V ++N+ +T D + + NG++ W+ R+ P Sbjct: 122 CRKNLSLDHDMEPKLWSPNVCIVNSKSTKVHDSPKPNILLMIFPNGTI-WLNYRIRSEAP 180 Query: 479 ISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 568 M L N+P D C+ F S +N+ +++ Sbjct: 181 CQMNLRNFPLDSIRCSLVFESYSYNAADVE 210 >UniRef50_A7SRB3 Cluster: Predicted protein; n=3; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 331 Score = 42.3 bits (95), Expect = 0.014 Identities = 24/101 (23%), Positives = 49/101 (48%), Gaps = 1/101 (0%) Frame = +2 Query: 269 LQMNWIDKRLSWSAGEWG-CSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 445 L+ W + L W+ +G + + + +W PD+VL N + + + +S++G+ Sbjct: 62 LKCLWNNHLLRWNESHYGGIKSINIDPKLVWLPDIVLYNNGSMD--QFKTKVILSSDGTN 119 Query: 446 SWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 568 +W + + S+ + +P D Q CT FGS ++ +D Sbjct: 120 TWYAPSILRSRCSIDITFFPFDDQRCTLHFGSWTYDGLRVD 160 >UniRef50_A7S8M2 Cluster: Predicted protein; n=2; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 303 Score = 42.3 bits (95), Expect = 0.014 Identities = 39/153 (25%), Positives = 75/153 (49%), Gaps = 14/153 (9%) Frame = +2 Query: 125 SLSLMIDSLLATYD---RESPPDS---KIVVNLTLH-LRHANIRESESTVRILADLQMNW 283 SL ++D ++ YD R + PD+ I V+L + + ++ E ++ + ++ W Sbjct: 2 SLDELLDVMVNCYDNRVRPTYPDNGPVNIQVDLFIQSVSKFSVINMEYSMTLY--IRQRW 59 Query: 284 IDKRLSWSAGEWGCSTWLVSSE----RLWRPDVVLLNA--AATTAGD-YALRARVSNNGS 442 +D+RL++ G+ ++ + ++W PD ++N + T +G ++ R+S NGS Sbjct: 60 LDQRLAY--GDMFPEDFITLGQEMVSQIWTPDTYIVNKKQSMTNSGHGMSMFIRISRNGS 117 Query: 443 VSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 541 V + + M L N+P D Q C FK S Sbjct: 118 VIFSAENTLVLVCQMDLRNFPMDEQQCDFKIES 150 >UniRef50_UPI0000E47589 Cluster: PREDICTED: similar to gamma-aminobutyric acid A receptor beta 2S chain precursor - chicken; n=1; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to gamma-aminobutyric acid A receptor beta 2S chain precursor - chicken - Strongylocentrotus purpuratus Length = 418 Score = 41.9 bits (94), Expect = 0.018 Identities = 25/104 (24%), Positives = 50/104 (48%), Gaps = 3/104 (2%) Frame = +2 Query: 272 QMNWIDKRLSWSAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGS 442 + +W D+RLS+ S + +ER+W PD N + D + R ++G+ Sbjct: 11 RQHWKDERLSYDPCLGNVSLSGILAERIWVPDTYFPNDKRSFVHDVTVTNKLLRFHHDGT 70 Query: 443 VSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFV 574 +++ R+ M L ++P D Q C+ + S + + +++FV Sbjct: 71 ITYGMRITSVASCYMDLVHYPMDEQNCSLEIESYGYTTADVNFV 114 >UniRef50_Q4SRT3 Cluster: Chromosome undetermined SCAF14492, whole genome shotgun sequence; n=3; Clupeocephala|Rep: Chromosome undetermined SCAF14492, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 457 Score = 41.9 bits (94), Expect = 0.018 Identities = 27/125 (21%), Positives = 58/125 (46%), Gaps = 8/125 (6%) Frame = +2 Query: 227 NIRESESTVRILADLQMNWIDKRLSWSAGEWG-CSTWLVSSERLWRPDVVL--LNAAATT 397 N+ E + + +W D+ L W+ ++ + + +W PD+++ L + T Sbjct: 39 NVDEKNQVLTTYVWYRQSWTDEFLVWNPEDFDEVKQVSMPTANVWVPDILINELLSPVTC 98 Query: 398 AGDYALR-----ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDE 562 + D VS++G V K + + T ++ + N+P D+Q C+ F S +H D+ Sbjct: 99 SVDVGKSPDIPYVYVSHDGLVRNYKPIQVVTACTLNIYNFPFDVQKCSLTFQSWLHTIDD 158 Query: 563 MDFVI 577 ++ + Sbjct: 159 INITL 163 >UniRef50_Q4SC79 Cluster: Chromosome undetermined SCAF14659, whole genome shotgun sequence; n=2; Euteleostomi|Rep: Chromosome undetermined SCAF14659, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 481 Score = 41.9 bits (94), Expect = 0.018 Identities = 33/135 (24%), Positives = 57/135 (42%), Gaps = 7/135 (5%) Frame = +2 Query: 140 IDSLLATYDRESPPD-SKIVVNLTLHLRHANI---RESESTVRILADLQMNWIDKRLSWS 307 +D L+ Y R P VN+ + + A+I E+ + L+ +W D RLS++ Sbjct: 32 LDDLMKGYARNFRPGIGGPPVNVAMAIEVASIDHISEANMEYTMTVFLRQSWHDDRLSYN 91 Query: 308 AGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTP 478 ++LW PD ++NA + D + R+ NG + + R+ + Sbjct: 92 HTNKTLGLDSRFVDKLWLPDTFIVNAKSAWFHDVTVENKLIRLQPNGVILYSSRITSTVA 151 Query: 479 ISMQLDNWPNDMQTC 523 M L +P D Q C Sbjct: 152 CDMDLTKYPMDEQEC 166 >UniRef50_Q8MM20 Cluster: Putative uncharacterized protein; n=3; Caenorhabditis|Rep: Putative uncharacterized protein - Caenorhabditis elegans Length = 428 Score = 41.9 bits (94), Expect = 0.018 Identities = 45/163 (27%), Positives = 72/163 (44%), Gaps = 11/163 (6%) Frame = +2 Query: 110 CENATSL--SLMIDSLLATYDRESPPDSKIVVNLTLHLRHANIRESESTVRILADLQMN- 280 C N T + L+ID L Y++ P ++ V + + ++ SE T DL MN Sbjct: 54 CANDTEIIDHLLIDRALY-YNKHKLPSPQVDVRIEMWVQEVT-SVSELTQDFEIDLYMNE 111 Query: 281 -WIDKRLSW---SAGEWGCS-TWLVSSERLWRPDVVLLNA--AATTAGDYA-LRARVSNN 436 W D L++ + + S W V + +W P+ +N+ A + + + V N Sbjct: 112 YWTDPGLAYDILNPCQGNLSFDWAVM-QNIWTPNTCFINSKKAQLHSSPFTNVFLMVFPN 170 Query: 437 GSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEM 565 GSV R+ + P M L +P D CT F S +N DE+ Sbjct: 171 GSVWSNWRIKSTGPCVMDLTKFPMDSIECTLTFESFNYNKDEV 213 >UniRef50_A7SDF1 Cluster: Predicted protein; n=2; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 273 Score = 41.9 bits (94), Expect = 0.018 Identities = 36/153 (23%), Positives = 69/153 (45%), Gaps = 10/153 (6%) Frame = +2 Query: 137 MIDSLLATYDRESPP---DSKIVVNLTLHLRH-ANIRESESTVRILADLQMNWIDKRLSW 304 +I+ L A YD+ P D ++ L++ NI+E+ ++ + W + RL Sbjct: 4 IINKLFADYDKTLRPGDGDGPTLITADLYVSSFGNIQETNMEYKVFGFFRQYWREDRL-- 61 Query: 305 SAGEWGCSTWLVSSE--RLWRPDVVLLNAAATTAG--DYALRARV--SNNGSVSWIKRLD 466 AG+ + L E +W+PD NA + D ++ + V +GSV + + + Sbjct: 62 -AGKHNKTVILTGKEIDNMWKPDPFCNNARESNLRETDESISSMVFLEPDGSVLYSRLII 120 Query: 467 ISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEM 565 ++ +M L +P D Q C K S + ++ + Sbjct: 121 VTAECNMNLRFFPMDEQKCYLKLSSYSYTTENI 153 >UniRef50_A7RTX5 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 386 Score = 41.5 bits (93), Expect = 0.024 Identities = 27/115 (23%), Positives = 40/115 (34%), Gaps = 5/115 (4%) Frame = +2 Query: 251 VRILADLQMNWIDKRLSWSAGEWGCSTWLVSSERLWRPDVVLLN-AAATTAGDYALRAR- 424 + + A + W L WS + S E +W PD L N AG Sbjct: 76 ITVNAWILQTWTHPVLKWSPRRRNVTKTRFSIEEVWVPDTALFNNGEKAVAGRQKFFESS 135 Query: 425 ---VSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVID 580 ++ +G W ++ + WP D CT F SR + + EM D Sbjct: 136 DVIMTYDGKAKWRTYATLTNKCKLNAKFWPMDEHVCTLTFSSRRYTASEMKIQSD 190 >UniRef50_UPI00015B4D8A Cluster: PREDICTED: similar to glutamate-gated chloride channel; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to glutamate-gated chloride channel - Nasonia vitripennis Length = 510 Score = 41.1 bits (92), Expect = 0.032 Identities = 31/130 (23%), Positives = 58/130 (44%), Gaps = 6/130 (4%) Frame = +2 Query: 170 ESPPDSKIVVNLTLHLRH-ANIRESESTVRILADLQMNWIDKRLSWS--AGEWGCSTWLV 340 E+ D +V + L +R A I + + + + W+D+RL ++ G+ T L Sbjct: 56 ENGTDGPAIVRVNLFVRSIATISDIKMEYSVQLTFREQWVDERLRFNDFGGKLKYLT-LT 114 Query: 341 SSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPND 511 + R+W PD+ N + + R+ +GSV + R+ ++ M L +P D Sbjct: 115 DASRVWMPDLFFANEKEGHFHNIIMPNVYIRIFPDGSVLYSIRISLTLSCPMNLKLYPLD 174 Query: 512 MQTCTFKFGS 541 Q C+ + S Sbjct: 175 RQICSLRMAS 184 >UniRef50_UPI0000E4929C Cluster: PREDICTED: similar to nicotinic acetylcholine receptor beta 1 subunit variant 1; n=1; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to nicotinic acetylcholine receptor beta 1 subunit variant 1 - Strongylocentrotus purpuratus Length = 472 Score = 41.1 bits (92), Expect = 0.032 Identities = 27/96 (28%), Positives = 47/96 (48%), Gaps = 5/96 (5%) Frame = +2 Query: 269 LQMNWIDKRLSWSAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGD-YALR---ARVSN 433 +++ W D RLSW+ E+ +L + E +W P V++ N+A + D +A+ A + + Sbjct: 78 VELMWKDPRLSWNESEYDGIQYLNLDPETIWMPRVIMQNSAMESVEDPFAMHRSYAIIFS 137 Query: 434 NGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 541 +G + T + N+P D QTCT S Sbjct: 138 DGYIRVTVPARFVTFCLTNVVNFPFDNQTCTVTVSS 173 >UniRef50_Q4SJX0 Cluster: Chromosome 1 SCAF14573, whole genome shotgun sequence; n=1; Tetraodon nigroviridis|Rep: Chromosome 1 SCAF14573, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 371 Score = 41.1 bits (92), Expect = 0.032 Identities = 37/139 (26%), Positives = 59/139 (42%), Gaps = 7/139 (5%) Frame = +2 Query: 146 SLLATYDRESPP----DSKIVVNLTLHLRHANIRESESTVRILADLQMNWIDKRLSWSAG 313 S AT R+ PP D V++ L L H + + Q W DKRLS+S Sbjct: 52 SQCATSRRKCPPRPRCDHTSVLDGPL-LTHWTQADMAHDYTLTMYFQQAWRDKRLSYSEI 110 Query: 314 EWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPIS 484 + + +++LW PD LN + ++ R+ +G+V + R+ + Sbjct: 111 AYNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACM 170 Query: 485 MQLDNWPNDMQTCTFKFGS 541 M L +P D Q CT + S Sbjct: 171 MDLRRYPLDEQNCTLEIES 189 >UniRef50_Q7PTU5 Cluster: ENSANGP00000015420; n=2; Anopheles gambiae str. PEST|Rep: ENSANGP00000015420 - Anopheles gambiae str. PEST Length = 238 Score = 41.1 bits (92), Expect = 0.032 Identities = 32/133 (24%), Positives = 56/133 (42%), Gaps = 7/133 (5%) Frame = +2 Query: 197 VNLTLH--LRHANIRESESTVRILADLQMNWIDKRLSWSAGEWGCSTWL-VSSERLWRPD 367 +N+T + L +I E S + + M W D L+W+A +W T L ++++ +W P Sbjct: 60 INITTYAVLYSFDISEYRSVMSFQVNYYMRWQDSSLAWNASDWSNITTLNINNDEIWSPQ 119 Query: 368 VVLLNAAATTAGDYAL---RARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFG 538 +++ + + NG VS IS S WP + C F Sbjct: 120 FENIDSDYEEQPSVSCLNPDCLLRVNGYVSCSPVCRISAKCSSDYSRWPFNTLVCRMWFT 179 Query: 539 SR-MHNSDEMDFV 574 +R DE++F+ Sbjct: 180 NRDKELVDEVNFL 192 >UniRef50_Q6U4B7 Cluster: Nicotinic acetylcholine receptor alpha 3 subunit; n=2; Nilaparvata lugens|Rep: Nicotinic acetylcholine receptor alpha 3 subunit - Nilaparvata lugens (Brown planthopper) Length = 575 Score = 41.1 bits (92), Expect = 0.032 Identities = 35/152 (23%), Positives = 63/152 (41%), Gaps = 6/152 (3%) Frame = +2 Query: 137 MIDSLLATYDRESPP----DSKIVVNLTLHLRHANIRESESTVRIL-ADLQMNWIDKRLS 301 + D LL+ Y++ P +++V L L L ++ +++ L++ W D + Sbjct: 31 LYDDLLSNYNKLIRPVGNNSDRLLVKLGLKLSQLIDVNGKNQIKVTNVWLEVTWYDYKGH 90 Query: 302 WSAGEWGCSTWLVSSERL-WRPDVVLLNAAATTAGDYALRARVSNNGSVSWIKRLDISTP 478 W+ +G L L W PD+VL N A + V W + Sbjct: 91 WNPASYGGVDDLYVPLLLHWGPDIVLYNNADGKY-EVVTYGTAGILHKVEWKPPAIYKSF 149 Query: 479 ISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFV 574 + ++ +P D Q C KFGS +N ++D + Sbjct: 150 CEIDVEYFPFDEQKCVMKFGSWTYNGAQVDLL 181 >UniRef50_Q6U4B5 Cluster: Nicotinic acetylcholine receptor beta 1 subunit; n=5; Neoptera|Rep: Nicotinic acetylcholine receptor beta 1 subunit - Nilaparvata lugens (Brown planthopper) Length = 530 Score = 41.1 bits (92), Expect = 0.032 Identities = 29/108 (26%), Positives = 47/108 (43%), Gaps = 9/108 (8%) Frame = +2 Query: 281 WIDKRLSWSAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYALRAR------VSNNG 439 W D W +G + L + ++W+PD+VL N A G Y ++ + + NG Sbjct: 91 WSDSLQLWDEAHYGGVSHLRLPPGKVWKPDIVLFNNAD---GHYFVKYKSHQQDMIRPNG 147 Query: 440 SVSWIKRLDISTPISMQLD--NWPNDMQTCTFKFGSRMHNSDEMDFVI 577 + W+ S +D +P D QTC KFGS ++D + Sbjct: 148 ELIWLPPAIFHDRSSCTIDVKYFPFDEQTCVMKFGSWTFPGKQVDLAL 195 >UniRef50_A7SN20 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 114 Score = 41.1 bits (92), Expect = 0.032 Identities = 29/108 (26%), Positives = 48/108 (44%), Gaps = 8/108 (7%) Frame = +2 Query: 281 WIDKRLSWSAGEW-GCSTWLVSSERLWRPDVVL---LNAAATTAG---DYALRARVSNNG 439 W + W+A E+ G +V S ++W PDV L +N AG Y + ++G Sbjct: 1 WHHPYMRWNASEFDGIKEVMVDSSQIWVPDVTLYNNINEQDHKAGGRSTYKTDVNIYSDG 60 Query: 440 SVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDF-VID 580 W + + + +P D QTC +F S +S +M+ V+D Sbjct: 61 RAVWRSPAIFKSTCDVYVMYFPFDKQTCYLRFSSWRMDSSKMELRVLD 108 >UniRef50_UPI0000584BCE Cluster: PREDICTED: hypothetical protein; n=1; Strongylocentrotus purpuratus|Rep: PREDICTED: hypothetical protein - Strongylocentrotus purpuratus Length = 577 Score = 40.7 bits (91), Expect = 0.043 Identities = 22/103 (21%), Positives = 52/103 (50%), Gaps = 3/103 (2%) Frame = +2 Query: 236 ESESTVRILADLQMNWIDKRLSWSAGEWGCSTWLVSSERLWRPDVVL---LNAAATTAGD 406 E+ + ++ +++ W+D+ L W E+ + ++ + +W P++ L ++ + D Sbjct: 62 ETNQVITLVVYVRLMWVDEYLQWDPAEYDRTIMIIPKD-IWLPELTLDENVDRDFISFPD 120 Query: 407 YALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKF 535 + A + +G+V+W I+T + + +P D+Q CT F Sbjct: 121 TYITA--TPDGTVNWFFPAVITTTCKVDVRFFPFDIQECTLTF 161 >UniRef50_UPI000065DFE4 Cluster: 5-hydroxytryptamine 3 receptor precursor (5-HT-3) (Serotonin-gated ion channel receptor) (5-HT3R).; n=1; Takifugu rubripes|Rep: 5-hydroxytryptamine 3 receptor precursor (5-HT-3) (Serotonin-gated ion channel receptor) (5-HT3R). - Takifugu rubripes Length = 488 Score = 40.7 bits (91), Expect = 0.043 Identities = 25/125 (20%), Positives = 58/125 (46%), Gaps = 8/125 (6%) Frame = +2 Query: 227 NIRESESTVRILADLQMNWIDKRLSWSAGEWG-CSTWLVSSERLWRPDVVLLN--AAATT 397 N+ E + + +W D+ L W+ ++ + + +W PD+++ ++ T Sbjct: 39 NVDEKNQVLTTYVWYRQSWTDEFLVWNPEDFDEVKQVSIPTANVWVPDILINEFLSSVTC 98 Query: 398 AGDYALR-----ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDE 562 + D V+++G V K + + T ++ + N+P D+Q C+ F S +H D+ Sbjct: 99 SVDVGKSPDIPYVYVTHDGLVRNYKPIQVVTACTLNIYNFPFDVQKCSLTFQSWLHTIDD 158 Query: 563 MDFVI 577 ++ + Sbjct: 159 INITL 163 >UniRef50_A4TVG5 Cluster: Glycine receptor, alpha 4 subunit; n=1; Magnetospirillum gryphiswaldense|Rep: Glycine receptor, alpha 4 subunit - Magnetospirillum gryphiswaldense Length = 356 Score = 40.7 bits (91), Expect = 0.043 Identities = 37/132 (28%), Positives = 56/132 (42%), Gaps = 10/132 (7%) Frame = +2 Query: 230 IRESESTVRILADLQMNWIDKRLSW-----SAG--EWGCSTWLVSSERLWRPDVVLLNAA 388 I E+E T D+++ W D RL++ +AG E+ +W P VV N Sbjct: 48 ITENEGTFTATVDMRLRWRDLRLAYPAEAKAAGYQEYRNDAAEKRLAEIWNPGVVFSNMV 107 Query: 389 ATTAGDYALRA-RVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMH--NSD 559 Y R R+S NG V ++R + S LD +P D Q SR+ Sbjct: 108 GEPT--YQKRGLRISPNGQVELMQRTTATFTASFPLDKFPFDRQKLNVDLVSRLEPIQRV 165 Query: 560 EMDFVIDKRIYS 595 ++DF D+ +S Sbjct: 166 QLDFRQDELEFS 177 >UniRef50_O97141 Cluster: Nicotinic acetylcholine beta subunit homolog; n=1; Haementeria ghilianii|Rep: Nicotinic acetylcholine beta subunit homolog - Haementeria ghilianii (Amazon leech) Length = 233 Score = 40.7 bits (91), Expect = 0.043 Identities = 36/146 (24%), Positives = 60/146 (41%), Gaps = 2/146 (1%) Frame = +2 Query: 110 CENATSLSLMIDSLLATYDRE-SPPDSKIVVNLTLHLRHANIRESESTVRILADLQMNWI 286 C + + + L Y++E P D+ + L H + E V + + +W Sbjct: 19 CSHLQGQTKLWKKLFDHYNKELEPEDAGLKFGLAFVRAHYEKQSHEVHVHVWE--RYSWT 76 Query: 287 DKRLSWSAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVSWIKRL 463 DKRLSW E+ G ++ VS + LW PD L + AL +++ G + ++ + Sbjct: 77 DKRLSWEPSEFDGVTSLRVSHDHLWLPDFQLYHGFEERVETKAL---LTHEGHLVYVPAV 133 Query: 464 DISTPISMQLDNWPNDMQTCTFKFGS 541 T + N C FK GS Sbjct: 134 LYKT----HCEKGANHSLHCHFKVGS 155 >UniRef50_Q2PMX5 Cluster: GABA receptor; n=1; Tetranychus urticae|Rep: GABA receptor - Tetranychus urticae (Two-spotted spider mite) Length = 585 Score = 40.3 bits (90), Expect = 0.056 Identities = 35/125 (28%), Positives = 54/125 (43%), Gaps = 8/125 (6%) Frame = +2 Query: 191 IVVNLTLHLRHANIRESESTVRILADLQMN--WIDKRLSWSAGEWGCSTWLVSSE---RL 355 + V +T+H+ + SE + AD W D RLS+ A G S LV +E ++ Sbjct: 70 VKVGVTMHILTIS-SVSEVQMDFTADFYFRQLWRDSRLSFKARH-GISQILVDAEVADKI 127 Query: 356 WRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCT 526 W PD N + + R+S++G V RL ++ M L +P D Q C Sbjct: 128 WVPDTFFANEKQAYFHEATTKNTFLRISHDGQVLRSIRLTVTASCPMNLQYFPMDRQKCN 187 Query: 527 FKFGS 541 + S Sbjct: 188 IEIES 192 >UniRef50_A7SDF0 Cluster: Predicted protein; n=2; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 349 Score = 39.9 bits (89), Expect = 0.075 Identities = 30/98 (30%), Positives = 48/98 (48%), Gaps = 6/98 (6%) Frame = +2 Query: 281 WIDKRLSWSAGEWGCSTWLVSSE--RLWRPDVVLLNA--AATTAGDYALRARVS--NNGS 442 W D+RL A S L E ++WRPD NA ++ TA D + + ++ NG Sbjct: 6 WKDERL---ANRLNKSVVLKGDEITKMWRPDPFCYNARESSLTASDDDINSMMTIHPNGD 62 Query: 443 VSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNS 556 V + + I+ M+L ++P D Q C K GS +++ Sbjct: 63 VVYSRMTIITAECEMKLHDFPMDEQQCHLKLGSYSYST 100 >UniRef50_P54244 Cluster: Acetylcholine receptor subunit alpha-type deg-3 precursor; n=2; Caenorhabditis|Rep: Acetylcholine receptor subunit alpha-type deg-3 precursor - Caenorhabditis elegans Length = 564 Score = 39.9 bits (89), Expect = 0.075 Identities = 30/157 (19%), Positives = 65/157 (41%), Gaps = 12/157 (7%) Frame = +2 Query: 188 KIVVNLTLHLRHANIRESESTVRILADLQMNWIDKRLSWSAGEWG-CSTWLVSSERLWRP 364 K+ ++++L+ + + E +++ + W D+ L W+ E+G ++ ++ LW P Sbjct: 79 KVHISISLY-QIIEVDEPSQNIKLNVWMIQKWRDEYLDWNPNEYGMINSTIIPFHHLWIP 137 Query: 365 DVVLLNAAATTAGD---YALRARVSN------NGSVSWIKRLDISTPISMQLDNWPNDMQ 517 D L N+ + + Y SN +S++ + + + +P D Q Sbjct: 138 DTYLYNSVKMSRDETERYMNIQATSNYWKGEKGAELSFLYPAIYTITCRLNIRFFPYDRQ 197 Query: 518 TCTFKFGSRMHNSDEMDFVIDKRI--YSMFESXAWDV 622 CT S ++ +D+ D + S + W V Sbjct: 198 NCTLTISSWTNSKSALDYYADTEVSMQSFIPNEEWQV 234 >UniRef50_Q9U358 Cluster: Putative uncharacterized protein acc-4; n=2; Caenorhabditis|Rep: Putative uncharacterized protein acc-4 - Caenorhabditis elegans Length = 408 Score = 39.5 bits (88), Expect = 0.099 Identities = 33/152 (21%), Positives = 67/152 (44%), Gaps = 9/152 (5%) Frame = +2 Query: 137 MIDSLLATYDR-ESPPDSKIVVNLTLHLRHAN-IRESESTVRILADLQMNWIDKRLSWSA 310 +I +L Y++ + P +VV++ + ++ + I E S + + W D L++S Sbjct: 55 IIAQILDGYNKLDLPGGGHVVVSIEIWVQEVSKIIEITSEFELDIYVTERWTDPSLAYSH 114 Query: 311 GEWGCSTWLVSS----ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDI 469 S V ++W P +N+ + + ++ +NGS+ R+ + Sbjct: 115 LNPCKSNMSVDGATILNKIWNPHACFVNSKLANIHESPFKNIFLQIYSNGSIWHNYRIKL 174 Query: 470 STPISMQLDNWPNDMQTCTFKFGSRMHNSDEM 565 + P S L +P D Q C + S HN+D++ Sbjct: 175 TGPCSSTLRTFPIDQQRCMLFYESFTHNTDQV 206 >UniRef50_Q9TVI7 Cluster: Putative uncharacterized protein; n=2; Caenorhabditis|Rep: Putative uncharacterized protein - Caenorhabditis elegans Length = 538 Score = 39.5 bits (88), Expect = 0.099 Identities = 45/151 (29%), Positives = 67/151 (44%), Gaps = 12/151 (7%) Frame = +2 Query: 137 MIDSLLATYDRESPPDSKIV-VNLTLHL-RHANIRE--SESTVRILADLQMNWIDKRLSW 304 ++ LL+ YDR P K V V++ L + R + I E S ST+ IL W D LS+ Sbjct: 91 ILTELLSKYDRNLVPKMKGVDVDVELLIQRVSEISEIQSSSTMHIL--FSQIWHDPGLSF 148 Query: 305 SAGEWG-CSTWLVSSERL----WRPDVVLLNAAATTAGDYA---LRARVSNNGSVSWIKR 460 E C T L S R+ W P+V ++N+ + + + NG+V R Sbjct: 149 EHEEGAHCLTNLSLSHRMVDNIWLPNVCIVNSKGSAIHKSPTPNIFLAIFPNGTVWMNYR 208 Query: 461 LDISTPISMQLDNWPNDMQTCTFKFGSRMHN 553 + + +P M +P D CT F S N Sbjct: 209 VVVESPCEMDFSFFPMDRVMCTTIFESYAFN 239 >UniRef50_Q61KY4 Cluster: Putative uncharacterized protein CBG09157; n=2; Caenorhabditis|Rep: Putative uncharacterized protein CBG09157 - Caenorhabditis briggsae Length = 371 Score = 32.7 bits (71), Expect(2) = 0.11 Identities = 19/80 (23%), Positives = 38/80 (47%), Gaps = 6/80 (7%) Frame = +2 Query: 149 LLATYDRESPP--DSKIVVNLTLHLRHAN---IRESESTVRILADLQMNWIDKRLSWSAG 313 LL Y + + P +S ++N+T ++ N + E +++L +W D+ L+W Sbjct: 15 LLDDYYKNARPVRNSSSILNVTALIQIYNLVEVNEKNEQIKLLLWFPQSWRDEYLTWDPE 74 Query: 314 EW-GCSTWLVSSERLWRPDV 370 EW G ++ +W D+ Sbjct: 75 EWNGIEKIIIPKAMIWLVDL 94 Score = 25.8 bits (54), Expect(2) = 0.11 Identities = 11/37 (29%), Positives = 23/37 (62%) Frame = +2 Query: 461 LDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDF 571 +D++ P+S+ ++P D Q C +FGS + ++ + F Sbjct: 92 VDLTCPMSVS--SFPFDSQLCALQFGSWSYPNNVLSF 126 >UniRef50_Q9XTE5 Cluster: Putative uncharacterized protein lgc-31; n=3; Caenorhabditis|Rep: Putative uncharacterized protein lgc-31 - Caenorhabditis elegans Length = 503 Score = 39.1 bits (87), Expect = 0.13 Identities = 27/121 (22%), Positives = 53/121 (43%), Gaps = 7/121 (5%) Frame = +2 Query: 281 WIDKRLSWSAGEW-GCSTWLVSSERLWRPDVVL---LNAAATTAGDYALRARVSNNGSVS 448 W D+ L W+ + G +SS +W P+ L LN RV+ G V Sbjct: 12 WEDEFLKWNPSSYEGAEEIFLSSSDIWIPEFSLYYSLNFNDAVKLQSNNDVRVNYTGQVR 71 Query: 449 WIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDKRIYSM---FESXAWD 619 + + + + +P D+Q C+ FGS H++D + + + + S+ +++ W+ Sbjct: 72 YYIPFSSESLCKLDVKFFPFDVQQCSLLFGSWAHSNDSIKYSLYSQNLSLIDFYDNQEWE 131 Query: 620 V 622 + Sbjct: 132 L 132 >UniRef50_O61884 Cluster: Acetylcholine receptor protein 23; n=2; Caenorhabditis|Rep: Acetylcholine receptor protein 23 - Caenorhabditis elegans Length = 545 Score = 39.1 bits (87), Expect = 0.13 Identities = 34/138 (24%), Positives = 57/138 (41%), Gaps = 9/138 (6%) Frame = +2 Query: 185 SKIVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWSAGEWGCSTWLVSS-ERLW 358 S I V L+L L + E + + + A W+D+ L W E+ T +++ + +W Sbjct: 50 SPINVTLSLQLYQIIQVNEPQQYLLLNAWAVERWVDQMLGWDPSEFDNETEIMARHDDIW 109 Query: 359 RPDVVLLNA------AATTAGDYALRARVSNNGS-VSWIKRLDISTPISMQLDNWPNDMQ 517 PD L N+ A+ L N G+ V + + L +P D Q Sbjct: 110 LPDTTLYNSLEMDDSASKKLTHVKLTTLGKNQGAMVELLYPTIYKISCLLNLKYFPFDTQ 169 Query: 518 TCTFKFGSRMHNSDEMDF 571 TC FGS ++ +D+ Sbjct: 170 TCRMTFGSWSFDNSLIDY 187 >UniRef50_A7RNN1 Cluster: Predicted protein; n=2; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 317 Score = 39.1 bits (87), Expect = 0.13 Identities = 26/115 (22%), Positives = 53/115 (46%), Gaps = 7/115 (6%) Frame = +2 Query: 281 WIDKRLSWSAGEWG-CSTWLVSSERLWRPDVVLLNAA---ATTAG---DYALRARVSNNG 439 W + L W+ ++G T V+ +W PD+VL N + +G + + ++G Sbjct: 72 WENPFLVWNESDYGGVHTLHVTFNDVWVPDIVLYNNGDPDLSLSGFTEKFKTFIILHSSG 131 Query: 440 SVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDKRIYSMFE 604 + +W+ + + + +P D QTC+ FGS +++ + + + YS E Sbjct: 132 TCTWMSPTTFKSSCKLDITKFPFDSQTCSMTFGSWTYDNRLLSMDLLDKQYSHTE 186 >UniRef50_A7RF65 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 290 Score = 39.1 bits (87), Expect = 0.13 Identities = 36/139 (25%), Positives = 63/139 (45%), Gaps = 10/139 (7%) Frame = +2 Query: 140 IDSLLATYDRESPPDSKI-VVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWS 307 +++LL YD+ P S +N+T+ L R +IRE E + L W D RL+ + Sbjct: 9 MNNLLRNYDKRIRPYSNTDKLNITVQLAVERFGDIREKEMDFSLEVYLNQTWHDDRLNHT 68 Query: 308 AGEWGCSTWLVSSE---RLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDI 469 ++S E +W+PD ++L + T + + ++G+V RL + Sbjct: 69 LDH----PIILSGEFKGSVWQPDTIILYVRSLTVYNSLSEPSSITIYSDGTVRSTVRLAL 124 Query: 470 STPISMQLDNWPNDMQTCT 526 M L ++P D Q C+ Sbjct: 125 VINCLMDLRDYPLDEQECS 143 >UniRef50_UPI00015B58ED Cluster: PREDICTED: similar to GABA-gated ion channel; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to GABA-gated ion channel - Nasonia vitripennis Length = 513 Score = 38.7 bits (86), Expect = 0.17 Identities = 29/107 (27%), Positives = 46/107 (42%), Gaps = 3/107 (2%) Frame = +2 Query: 230 IRESESTVRILADLQMNWIDKRLSWSAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDY 409 I E I L W D+RL++S + + +E++W PD N + D Sbjct: 89 ISEVNMDYTITMYLNQYWKDERLAFSHEKEILTLSGDFAEKIWVPDTFFANDKHSFLHDV 148 Query: 410 ALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 541 R R++ +GSV++ R + M L +P D Q CT + S Sbjct: 149 TERNKLVRLAGDGSVTYGMRFTTTLACMMDLHYYPLDSQNCTVEIES 195 >UniRef50_Q60NW3 Cluster: Putative uncharacterized protein CBG22525; n=1; Caenorhabditis briggsae|Rep: Putative uncharacterized protein CBG22525 - Caenorhabditis briggsae Length = 393 Score = 38.7 bits (86), Expect = 0.17 Identities = 32/157 (20%), Positives = 71/157 (45%), Gaps = 11/157 (7%) Frame = +2 Query: 134 LMIDSLLATYDRESPPDSKIVVNLTLHLRHANIRESESTVRILADLQMNWIDKRLSWSAG 313 ++I++ + R S P + I + HLR ++ +S+ T+ + + W+D+R W Sbjct: 40 ILINATASMPGRGSNPITAITMLHVDHLR--DLDQSKGTMSMSLSFLVTWMDERFRWDPK 97 Query: 314 EWGCSTWLVSSER------LWRPDVVLLNAAATTAG-----DYALRARVSNNGSVSWIKR 460 ++ S V+ ++ W P++ + + ++ + + V ++G+V R Sbjct: 98 DYH-SVRSVNGDKPSWSSAFWVPNIQIADMPSSQKSPGLFMNPGVEITVESSGTVKAFVR 156 Query: 461 LDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDF 571 ++ P ++P D Q C+F S + +DE F Sbjct: 157 TSMTIPCYFNFGDFPRDYQNCSFTLLSPYY-ADEFQF 192 >UniRef50_O01792 Cluster: Putative uncharacterized protein; n=2; Caenorhabditis|Rep: Putative uncharacterized protein - Caenorhabditis elegans Length = 469 Score = 38.7 bits (86), Expect = 0.17 Identities = 37/150 (24%), Positives = 72/150 (48%), Gaps = 10/150 (6%) Frame = +2 Query: 137 MIDSLLATYDRESPPDSKIVVNLTLHLRHANIRESESTVRILADLQMN--WIDKRLSWSA 310 ++D ++A Y R S P + + V + + ++ + S + AD+ + W D RL++S Sbjct: 35 ILDVIMANYSR-SLPGNPVGVQVEVTVQDV-MELSVLSNSFTADIWFSSIWYDPRLAYSH 92 Query: 311 GEWGCSTWLVSSER----LWRPDVVLLNAAAT---TAGDYALRARVSNNGSVSWIK-RLD 466 + C L +R +W P+V ++N + + + + NG++ W+ R+ Sbjct: 93 LD-NCRQNLSFDDRFEKLIWSPNVCIVNTKSAHVHRSPKPNVLLMLLPNGTI-WLNYRIR 150 Query: 467 ISTPISMQLDNWPNDMQTCTFKFGSRMHNS 556 + +P SM L +P D Q C F S +N+ Sbjct: 151 VQSPCSMDLARFPIDTQYCQLVFESYSYNT 180 Database: uniref50 Posted date: Oct 5, 2007 11:19 AM Number of letters in database: 575,637,011 Number of sequences in database: 1,657,284 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.279 0.0580 0.190 Matrix: BLOSUM62 Gap Penalties: Existence: 9, Extension: 2 Number of Hits to DB: 723,146,390 Number of Sequences: 1657284 Number of extensions: 15407969 Number of successful extensions: 46024 Number of sequences better than 10.0: 291 Number of HSP's better than 10.0 without gapping: 43320 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 45744 length of database: 575,637,011 effective HSP length: 99 effective length of database: 411,565,895 effective search space used: 70377768045 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 37 (14.9 bits) X3: 62 (25.0 bits) S1: 41 (21.7 bits)
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