BLASTX 2.2.12 [Aug-07-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= BmNP01_FL5_E18 (911 letters) Database: uniref50 1,657,284 sequences; 575,637,011 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value UniRef50_UPI0000D55EDD Cluster: PREDICTED: similar to CG11822-PA... 85 3e-15 UniRef50_Q2XWK6 Cluster: Nicotinic acetylcholine receptor subuni... 75 2e-12 UniRef50_A7RFJ5 Cluster: Predicted protein; n=2; Nematostella ve... 75 2e-12 UniRef50_Q4S3I4 Cluster: Chromosome 1 SCAF14749, whole genome sh... 75 3e-12 UniRef50_Q4S3I6 Cluster: Chromosome 1 SCAF14749, whole genome sh... 73 1e-11 UniRef50_Q2XWK8 Cluster: Nicotinic acetylcholine receptor subuni... 72 2e-11 UniRef50_Q60KR8 Cluster: Putative uncharacterized protein CBG239... 71 5e-11 UniRef50_P48182 Cluster: Acetylcholine receptor subunit beta-typ... 71 5e-11 UniRef50_Q17BK7 Cluster: Nicotinic acetylcholine receptor, beta-... 70 7e-11 UniRef50_UPI0000E49401 Cluster: PREDICTED: similar to alpha 10 s... 69 2e-10 UniRef50_Q4S864 Cluster: Chromosome 5 SCAF14709, whole genome sh... 69 2e-10 UniRef50_P30532 Cluster: Neuronal acetylcholine receptor subunit... 69 2e-10 UniRef50_UPI00015A3E3C Cluster: Neuronal acetylcholine receptor ... 68 3e-10 UniRef50_Q5BW84 Cluster: SJCHGC08361 protein; n=1; Schistosoma j... 67 5e-10 UniRef50_Q2XWL1 Cluster: Nicotinic acetylcholine receptor subuni... 67 5e-10 UniRef50_A0EIZ7 Cluster: Nicotinic acetylcholine receptor alpha9... 67 5e-10 UniRef50_Q9N4M3 Cluster: Acetylcholine receptor protein 6; n=1; ... 67 7e-10 UniRef50_P91766 Cluster: Acetylcholine receptor subunit alpha-li... 67 7e-10 UniRef50_UPI0001560C7D Cluster: PREDICTED: similar to cholinergi... 66 9e-10 UniRef50_UPI00015B4A35 Cluster: PREDICTED: similar to nicotinic ... 66 1e-09 UniRef50_Q93329 Cluster: Putative uncharacterized protein lev-8;... 66 1e-09 UniRef50_Q27218 Cluster: Acetylcholine receptor subunit beta-typ... 66 1e-09 UniRef50_P17644 Cluster: Acetylcholine receptor subunit alpha-li... 66 1e-09 UniRef50_A7S3F7 Cluster: Predicted protein; n=1; Nematostella ve... 66 2e-09 UniRef50_Q7T2R4 Cluster: Nicotinic acetylcholine receptor alpha ... 65 3e-09 UniRef50_Q15822 Cluster: Neuronal acetylcholine receptor subunit... 65 3e-09 UniRef50_UPI00015B5C4C Cluster: PREDICTED: similar to GABA-gated... 64 4e-09 UniRef50_UPI0000EBE733 Cluster: PREDICTED: similar to nicotinic ... 64 4e-09 UniRef50_O44497 Cluster: Putative uncharacterized protein; n=2; ... 64 4e-09 UniRef50_Q24352 Cluster: Gamma-aminobutyric acid receptor alpha-... 64 4e-09 UniRef50_P11230 Cluster: Acetylcholine receptor subunit beta pre... 64 4e-09 UniRef50_UPI00015B4DDF Cluster: PREDICTED: similar to neurotrans... 64 5e-09 UniRef50_UPI0000E47C59 Cluster: PREDICTED: similar to alpha-9 ni... 64 5e-09 UniRef50_Q4RRI3 Cluster: Chromosome 16 SCAF15002, whole genome s... 64 5e-09 UniRef50_Q2XWK3 Cluster: Nicotinic acetylcholine receptor subuni... 64 5e-09 UniRef50_Q04844 Cluster: Acetylcholine receptor subunit epsilon ... 64 5e-09 UniRef50_UPI0000E47D8F Cluster: PREDICTED: similar to nicotinic ... 64 6e-09 UniRef50_Q66T35 Cluster: Nicotinic acetylcholine receptor subuni... 64 6e-09 UniRef50_P48180 Cluster: Acetylcholine receptor subunit alpha-ty... 64 6e-09 UniRef50_Q7T2S3 Cluster: Nicotinic acetylcholine receptor alpha ... 63 8e-09 UniRef50_Q8WSF7 Cluster: GABA A receptor alpha subunit; n=1; Apl... 63 8e-09 UniRef50_Q0GQR6 Cluster: GABA-gated ion channel; n=2; Apis melli... 63 8e-09 UniRef50_P17787 Cluster: Neuronal acetylcholine receptor subunit... 63 8e-09 UniRef50_P43681 Cluster: Neuronal acetylcholine receptor subunit... 63 8e-09 UniRef50_P04755 Cluster: Acetylcholine receptor subunit beta-lik... 63 8e-09 UniRef50_UPI0000E49402 Cluster: PREDICTED: similar to alpha 10 s... 63 1e-08 UniRef50_Q4RIA9 Cluster: Chromosome 8 SCAF15044, whole genome sh... 63 1e-08 UniRef50_Q2XWL0 Cluster: Nicotinic acetylcholine receptor subuni... 63 1e-08 UniRef50_A7UFK6 Cluster: Nicotinic acetylcholine receptor alpha ... 63 1e-08 UniRef50_A7SW63 Cluster: Predicted protein; n=3; Nematostella ve... 63 1e-08 UniRef50_P54245 Cluster: Uncharacterized acetylcholine receptor-... 63 1e-08 UniRef50_Q4S866 Cluster: Chromosome 5 SCAF14709, whole genome sh... 62 1e-08 UniRef50_P07510 Cluster: Acetylcholine receptor subunit gamma pr... 62 1e-08 UniRef50_A7RLP3 Cluster: Predicted protein; n=3; Nematostella ve... 62 2e-08 UniRef50_A7RHV9 Cluster: Predicted protein; n=3; Nematostella ve... 62 2e-08 UniRef50_A2TM48 Cluster: Nicotinic acetylcholine receptor alpha ... 62 2e-08 UniRef50_Q66T21 Cluster: Nicotinic acetylcholine receptor subuni... 62 3e-08 UniRef50_Q23022 Cluster: Acetylcholine receptor subunit alpha-ty... 62 3e-08 UniRef50_Q4SXG5 Cluster: Chromosome undetermined SCAF12416, whol... 61 3e-08 UniRef50_Q8JFN7 Cluster: Neuronal acetylcholine receptor subunit... 61 3e-08 UniRef50_Q65XS8 Cluster: Acetylcholine receptor protein 25; n=2;... 61 4e-08 UniRef50_Q2XWK5 Cluster: Nicotinic acetylcholine receptor subuni... 61 4e-08 UniRef50_Q29ND1 Cluster: GA17977-PA; n=3; Schizophora|Rep: GA179... 61 4e-08 UniRef50_O16926 Cluster: Acetylcholine receptor protein 15; n=2;... 61 4e-08 UniRef50_O46132 Cluster: Nicotinic acetylcholine receptor, alpha... 60 8e-08 UniRef50_A7RLM4 Cluster: Predicted protein; n=2; Nematostella ve... 60 8e-08 UniRef50_A0EIZ9 Cluster: Nicotinic acetylcholine receptor beta2 ... 60 8e-08 UniRef50_UPI0000D55E50 Cluster: PREDICTED: similar to AcetylChol... 60 1e-07 UniRef50_Q23355 Cluster: Putative uncharacterized protein acr-8;... 60 1e-07 UniRef50_A5H038 Cluster: Nicotinic acetylcholine receptor subuni... 60 1e-07 UniRef50_Q7Z6B2 Cluster: 5-hydroxytryptamine serotonin receptor ... 60 1e-07 UniRef50_UPI0000E49844 Cluster: PREDICTED: similar to nicotinic ... 59 1e-07 UniRef50_A7S622 Cluster: Predicted protein; n=1; Nematostella ve... 59 1e-07 UniRef50_A7RUG1 Cluster: Predicted protein; n=2; Nematostella ve... 59 1e-07 UniRef50_A6QL44 Cluster: Nicotinic acetylcholine receptor non-al... 59 1e-07 UniRef50_Q9U298 Cluster: Neuronal acetylcholine receptor subunit... 59 1e-07 UniRef50_UPI00015B5C6B Cluster: PREDICTED: similar to nicotinic ... 59 2e-07 UniRef50_UPI0000E48B7E Cluster: PREDICTED: similar to neuronal n... 59 2e-07 UniRef50_Q9GQ00 Cluster: Serotonin-gated chloride channel; n=4; ... 59 2e-07 UniRef50_A7SNK1 Cluster: Predicted protein; n=2; Nematostella ve... 59 2e-07 UniRef50_Q7KT97 Cluster: CG32975-PB, isoform B; n=69; Eumetazoa|... 58 2e-07 UniRef50_A7T134 Cluster: Predicted protein; n=1; Nematostella ve... 58 2e-07 UniRef50_A7RK99 Cluster: Predicted protein; n=2; Nematostella ve... 58 2e-07 UniRef50_UPI0000E47C58 Cluster: PREDICTED: similar to nicotinic ... 58 3e-07 UniRef50_P91197 Cluster: Acetylcholine receptor protein 11; n=2;... 58 4e-07 UniRef50_O62083 Cluster: Putative uncharacterized protein acr-19... 58 4e-07 UniRef50_O61519 Cluster: Ligand-gated ion channel protein 6; n=4... 58 4e-07 UniRef50_P25162 Cluster: Acetylcholine receptor subunit beta-lik... 58 4e-07 UniRef50_A7SI11 Cluster: Predicted protein; n=1; Nematostella ve... 57 5e-07 UniRef50_Q07001 Cluster: Acetylcholine receptor subunit delta pr... 57 5e-07 UniRef50_UPI0000E464AB Cluster: PREDICTED: similar to nicotinic ... 57 7e-07 UniRef50_UPI0000ECB6ED Cluster: Acetylcholine receptor subunit a... 57 7e-07 UniRef50_Q4RZC6 Cluster: Chromosome 1 SCAF14944, whole genome sh... 57 7e-07 UniRef50_UPI0000E4930A Cluster: PREDICTED: similar to nicotinic ... 56 9e-07 UniRef50_Q9GP98 Cluster: Acetylcholine receptor protein 22; n=3;... 56 9e-07 UniRef50_Q2XWL2 Cluster: Nicotinic acetylcholine receptor subuni... 56 9e-07 UniRef50_Q2XWK9 Cluster: Nicotinic acetylcholine receptor subuni... 56 9e-07 UniRef50_O18228 Cluster: Putative uncharacterized protein lgc-7;... 56 9e-07 UniRef50_A7S9T6 Cluster: Predicted protein; n=2; Nematostella ve... 56 9e-07 UniRef50_Q9UGM1 Cluster: Neuronal acetylcholine receptor subunit... 56 9e-07 UniRef50_UPI0000D56893 Cluster: PREDICTED: similar to CG6698-PA;... 56 1e-06 UniRef50_UPI0000E47621 Cluster: PREDICTED: similar to nicotinic ... 56 2e-06 UniRef50_Q6Q069 Cluster: Neuronal nicotinic acetylcholine Apisa7... 56 2e-06 UniRef50_Q17BK9 Cluster: Nicotinic acetylcholine receptor, putat... 56 2e-06 UniRef50_Q10052 Cluster: Gaba/glycine receptor family (See gbr) ... 56 2e-06 UniRef50_A7RS32 Cluster: Predicted protein; n=1; Nematostella ve... 56 2e-06 UniRef50_UPI000058896A Cluster: PREDICTED: similar to cholinergi... 55 2e-06 UniRef50_O17848 Cluster: Putative uncharacterized protein acr-18... 55 2e-06 UniRef50_A7RS33 Cluster: Predicted protein; n=1; Nematostella ve... 55 2e-06 UniRef50_Q21645 Cluster: Acetylcholine receptor protein 10; n=2;... 55 3e-06 UniRef50_A7S2N9 Cluster: Predicted protein; n=3; Nematostella ve... 55 3e-06 UniRef50_A7S2J7 Cluster: Predicted protein; n=1; Nematostella ve... 55 3e-06 UniRef50_Q60S81 Cluster: Neuronal acetylcholine receptor subunit... 55 3e-06 UniRef50_UPI00015B6212 Cluster: PREDICTED: similar to nicotinic ... 54 4e-06 UniRef50_UPI0000F2C37E Cluster: PREDICTED: similar to CHRNG prot... 54 4e-06 UniRef50_A7RNI2 Cluster: Predicted protein; n=3; Nematostella ve... 54 4e-06 UniRef50_A7RFJ2 Cluster: Predicted protein; n=1; Nematostella ve... 54 4e-06 UniRef50_P31644 Cluster: Gamma-aminobutyric acid receptor subuni... 54 4e-06 UniRef50_Q9XTY8 Cluster: Putative uncharacterized protein lgc-25... 54 5e-06 UniRef50_Q6TMY0 Cluster: Nicotinic acetylcholine receptor non-al... 54 5e-06 UniRef50_UPI00015A4976 Cluster: 5-hydroxytryptamine receptor 3 s... 54 7e-06 UniRef50_Q7PJX0 Cluster: ENSANGP00000022703; n=1; Anopheles gamb... 54 7e-06 UniRef50_Q86YW4 Cluster: Ligand-gated ion channel subunit; n=10;... 54 7e-06 UniRef50_Q2XWK4 Cluster: Nicotinic acetylcholine receptor subuni... 53 9e-06 UniRef50_P36544 Cluster: Neuronal acetylcholine receptor subunit... 53 9e-06 UniRef50_UPI0000E48474 Cluster: PREDICTED: similar to nicotinic ... 53 1e-05 UniRef50_Q6F6K3 Cluster: Acetylcholine receptor protein 17, isof... 53 1e-05 UniRef50_Q18556 Cluster: Putative uncharacterized protein acr-9;... 53 1e-05 UniRef50_Q2XWK7 Cluster: Nicotinic acetylcholine receptor subuni... 52 2e-05 UniRef50_Q0GQQ6 Cluster: Cys-loop ligand-gated ion channel subun... 52 2e-05 UniRef50_A7S2P0 Cluster: Predicted protein; n=4; Nematostella ve... 52 2e-05 UniRef50_UPI00006A0B5C Cluster: Gamma-aminobutyric-acid receptor... 52 2e-05 UniRef50_Q9GQU9 Cluster: Nicotinic acetylcholine receptor-like s... 52 2e-05 UniRef50_Q6TMY3 Cluster: Nicotinic acetylcholine receptor alpha ... 52 2e-05 UniRef50_Q4V4V5 Cluster: IP12579p; n=6; Endopterygota|Rep: IP125... 52 2e-05 UniRef50_A7RND6 Cluster: Predicted protein; n=1; Nematostella ve... 52 2e-05 UniRef50_UPI0000E473D1 Cluster: PREDICTED: similar to neuronal a... 52 3e-05 UniRef50_Q67X94 Cluster: Putative uncharacterized protein lgc-2;... 52 3e-05 UniRef50_Q4R170 Cluster: Putative uncharacterized protein; n=1; ... 52 3e-05 UniRef50_A7SLK4 Cluster: Predicted protein; n=2; Nematostella ve... 52 3e-05 UniRef50_A6XBS1 Cluster: Amorphous calcium carbonate binding pro... 52 3e-05 UniRef50_P18505 Cluster: Gamma-aminobutyric acid receptor subuni... 52 3e-05 UniRef50_UPI00006602DC Cluster: Homolog of Homo sapiens "5-hydro... 51 4e-05 UniRef50_P47870-2 Cluster: Isoform Long of P47870 ; n=22; Eumeta... 51 4e-05 UniRef50_Q4RR58 Cluster: Chromosome 14 SCAF15003, whole genome s... 51 4e-05 UniRef50_Q9VPQ8 Cluster: CG11822-PA, isoform A (Nicotinic acetyl... 51 4e-05 UniRef50_Q14DU4 Cluster: CHRNG protein; n=3; Euarchontoglires|Re... 51 4e-05 UniRef50_P34903 Cluster: Gamma-aminobutyric acid receptor subuni... 51 4e-05 UniRef50_P02708 Cluster: Acetylcholine receptor subunit alpha pr... 51 4e-05 UniRef50_Q9N5U8 Cluster: Acetylcholine receptor protein 21; n=2;... 51 5e-05 UniRef50_Q20828 Cluster: Putative uncharacterized protein; n=2; ... 51 5e-05 UniRef50_Q19351 Cluster: Ligand-gated ion channel protein 3; n=3... 51 5e-05 UniRef50_P45963 Cluster: Acetylcholine receptor subunit alpha-ty... 51 5e-05 UniRef50_Q6BET0 Cluster: Putative uncharacterized protein; n=2; ... 50 6e-05 UniRef50_A7S2G2 Cluster: Predicted protein; n=2; Nematostella ve... 50 6e-05 UniRef50_A2TM50 Cluster: Nicotinic acetylcholine receptor alpha ... 50 6e-05 UniRef50_Q95Y52 Cluster: Putative uncharacterized protein; n=2; ... 50 8e-05 UniRef50_Q621V5 Cluster: Putative uncharacterized protein CBG023... 50 8e-05 UniRef50_A7RR86 Cluster: Predicted protein; n=1; Nematostella ve... 50 8e-05 UniRef50_A7RLM5 Cluster: Predicted protein; n=1; Nematostella ve... 50 8e-05 UniRef50_UPI0000F1DA85 Cluster: PREDICTED: similar to MGC52789 p... 50 1e-04 UniRef50_UPI0000E47329 Cluster: PREDICTED: similar to novel chol... 50 1e-04 UniRef50_UPI0000586C99 Cluster: PREDICTED: similar to nicotinic ... 50 1e-04 UniRef50_UPI000069FF34 Cluster: UPI000069FF34 related cluster; n... 50 1e-04 UniRef50_Q22224 Cluster: Putative uncharacterized protein acr-14... 50 1e-04 UniRef50_P41849 Cluster: Uncharacterized glycine receptor-like p... 50 1e-04 UniRef50_A7S9T8 Cluster: Predicted protein; n=1; Nematostella ve... 49 2e-04 UniRef50_P48169 Cluster: Gamma-aminobutyric acid receptor subuni... 49 2e-04 UniRef50_UPI0000E47720 Cluster: PREDICTED: similar to alpha-9 ni... 48 3e-04 UniRef50_Q8TA51 Cluster: Putative uncharacterized protein; n=3; ... 48 3e-04 UniRef50_O44452 Cluster: Putative uncharacterized protein; n=2; ... 48 3e-04 UniRef50_Q9W288 Cluster: CG6698-PA; n=4; Sophophora|Rep: CG6698-... 48 3e-04 UniRef50_UPI00003CEF8B Cluster: R03E1.3; n=1; Caenorhabditis ele... 48 4e-04 UniRef50_Q4RLA7 Cluster: Chromosome 21 SCAF15022, whole genome s... 48 4e-04 UniRef50_Q9GUF0 Cluster: Ligand-gated ion channel protein 10; n=... 48 4e-04 UniRef50_A4FTX5 Cluster: CHRNB4 protein; n=1; Homo sapiens|Rep: ... 48 4e-04 UniRef50_UPI000069F132 Cluster: 5-hydroxytryptamine receptor 3 s... 47 6e-04 UniRef50_O14764 Cluster: Gamma-aminobutyric acid receptor subuni... 47 6e-04 UniRef50_Q4RN70 Cluster: Chromosome undetermined SCAF15016, whol... 47 8e-04 UniRef50_Q4W520 Cluster: Putative uncharacterized protein; n=1; ... 47 8e-04 UniRef50_Q2WF65 Cluster: Gaba/glycine receptor family (See gbr) ... 47 8e-04 UniRef50_O00591 Cluster: Gamma-aminobutyric acid receptor subuni... 47 8e-04 UniRef50_UPI0000E20C28 Cluster: PREDICTED: gamma-aminobutyric ac... 46 0.001 UniRef50_UPI0000EB6CC4 Cluster: glycine receptor, beta b; n=1; D... 46 0.001 UniRef50_UPI0000660F16 Cluster: Homolog of Homo sapiens "Splice ... 46 0.001 UniRef50_Q7NDN8 Cluster: Glr4197 protein; n=1; Gloeobacter viola... 46 0.001 UniRef50_A7T7Z5 Cluster: Predicted protein; n=1; Nematostella ve... 46 0.001 UniRef50_Q9UN88 Cluster: Gamma-aminobutyric acid receptor subuni... 46 0.001 UniRef50_UPI00015B60A2 Cluster: PREDICTED: similar to nicotinic ... 46 0.002 UniRef50_UPI0000F1E62D Cluster: PREDICTED: hypothetical protein;... 46 0.002 UniRef50_UPI0000E45D33 Cluster: PREDICTED: similar to nicotinic ... 46 0.002 UniRef50_Q4BXY7 Cluster: Neurotransmitter-gated ion-channel liga... 46 0.002 UniRef50_Q8MM20 Cluster: Putative uncharacterized protein; n=3; ... 46 0.002 UniRef50_Q7PTU5 Cluster: ENSANGP00000015420; n=2; Anopheles gamb... 46 0.002 UniRef50_A7S8Q4 Cluster: Predicted protein; n=3; Nematostella ve... 46 0.002 UniRef50_UPI00015B4D8A Cluster: PREDICTED: similar to glutamate-... 45 0.002 UniRef50_UPI000065F0EC Cluster: Homolog of Homo sapiens "5-hydro... 45 0.002 UniRef50_Q4SRT2 Cluster: Chromosome undetermined SCAF14492, whol... 45 0.002 UniRef50_Q93323 Cluster: Putative uncharacterized protein lgc-21... 45 0.002 UniRef50_O18276 Cluster: Gamma-aminobutyric acid receptor subuni... 45 0.002 UniRef50_UPI000058727F Cluster: PREDICTED: similar to Chain B, R... 45 0.003 UniRef50_UPI00006A0062 Cluster: UPI00006A0062 related cluster; n... 45 0.003 UniRef50_Q7ZTN5 Cluster: MGC52789 protein; n=1; Xenopus laevis|R... 45 0.003 UniRef50_Q4RU50 Cluster: Chromosome 1 SCAF14995, whole genome sh... 45 0.003 UniRef50_Q6U4B6 Cluster: Nicotinic acetylcholine receptor alpha ... 45 0.003 UniRef50_A7SRB3 Cluster: Predicted protein; n=3; Nematostella ve... 45 0.003 UniRef50_A7S763 Cluster: Predicted protein; n=1; Nematostella ve... 45 0.003 UniRef50_P25123 Cluster: Gamma-aminobutyric acid receptor subuni... 45 0.003 UniRef50_UPI0000E4906A Cluster: PREDICTED: similar to nicotinic ... 44 0.004 UniRef50_Q4SC79 Cluster: Chromosome undetermined SCAF14659, whol... 44 0.004 UniRef50_UPI0000E49D12 Cluster: PREDICTED: similar to acetylchol... 44 0.005 UniRef50_Q6U4B7 Cluster: Nicotinic acetylcholine receptor alpha ... 44 0.005 UniRef50_Q22085 Cluster: Putative uncharacterized protein lgc-17... 44 0.005 UniRef50_O17547 Cluster: GluClalpha2A protein; n=66; Chromadorea... 44 0.005 UniRef50_A7SDE9 Cluster: Predicted protein; n=1; Nematostella ve... 44 0.005 UniRef50_P34271 Cluster: Acetylcholine receptor-like protein cup... 44 0.005 UniRef50_Q4S0E0 Cluster: Chromosome 2 SCAF14781, whole genome sh... 44 0.007 UniRef50_Q61I41 Cluster: Putative uncharacterized protein CBG104... 44 0.007 UniRef50_A7RTF8 Cluster: Predicted protein; n=1; Nematostella ve... 44 0.007 UniRef50_A7SN20 Cluster: Predicted protein; n=1; Nematostella ve... 43 0.009 UniRef50_P54244 Cluster: Acetylcholine receptor subunit alpha-ty... 43 0.013 UniRef50_O16426 Cluster: Ligand-gated ion channel protein 1; n=2... 42 0.017 UniRef50_Q94900 Cluster: Glutamate-gated chloride channel precur... 42 0.017 UniRef50_UPI0000E4929C Cluster: PREDICTED: similar to nicotinic ... 42 0.022 UniRef50_A2BGE6 Cluster: Glycine receptor, alpha 4b; n=5; Danio ... 42 0.022 UniRef50_Q9U358 Cluster: Putative uncharacterized protein acc-4;... 42 0.022 UniRef50_A7SVS1 Cluster: Predicted protein; n=5; Nematostella ve... 42 0.022 UniRef50_A7RTX5 Cluster: Predicted protein; n=1; Nematostella ve... 42 0.022 UniRef50_O75311 Cluster: Glycine receptor subunit alpha-3 precur... 42 0.022 UniRef50_UPI0000E47589 Cluster: PREDICTED: similar to gamma-amin... 42 0.029 UniRef50_Q6U4B5 Cluster: Nicotinic acetylcholine receptor beta 1... 42 0.029 UniRef50_Q9XTE5 Cluster: Putative uncharacterized protein lgc-31... 41 0.038 UniRef50_Q9TVI7 Cluster: Putative uncharacterized protein; n=2; ... 41 0.038 UniRef50_Q9NA62 Cluster: Putative uncharacterized protein; n=1; ... 41 0.038 UniRef50_Q2PMX5 Cluster: GABA receptor; n=1; Tetranychus urticae... 41 0.038 UniRef50_A7SDF1 Cluster: Predicted protein; n=2; Nematostella ve... 41 0.038 UniRef50_A7RNN1 Cluster: Predicted protein; n=2; Nematostella ve... 41 0.038 UniRef50_A4TVG5 Cluster: Glycine receptor, alpha 4 subunit; n=1;... 41 0.050 UniRef50_O61884 Cluster: Acetylcholine receptor protein 23; n=2;... 41 0.050 UniRef50_A7S8M2 Cluster: Predicted protein; n=2; Nematostella ve... 41 0.050 UniRef50_A7S2G5 Cluster: Predicted protein; n=1; Nematostella ve... 41 0.050 UniRef50_UPI0000584BCE Cluster: PREDICTED: hypothetical protein;... 40 0.067 UniRef50_Q60NW3 Cluster: Putative uncharacterized protein CBG225... 40 0.067 UniRef50_O17402 Cluster: Putative uncharacterized protein; n=2; ... 40 0.067 UniRef50_Q9VGI0 Cluster: CG14723-PA, isoform A; n=12; Endopteryg... 40 0.088 UniRef50_Q21005 Cluster: Putative uncharacterized protein acc-1;... 40 0.12 UniRef50_O97141 Cluster: Nicotinic acetylcholine beta subunit ho... 40 0.12 UniRef50_A7SDF0 Cluster: Predicted protein; n=2; Nematostella ve... 40 0.12 UniRef50_A7RF65 Cluster: Predicted protein; n=1; Nematostella ve... 40 0.12 UniRef50_O76554 Cluster: Acetylcholine receptor subunit alpha-ty... 40 0.12 UniRef50_Q6QWI5 Cluster: Acetylcholine receptor 20 (63.9 kD) alt... 39 0.15 UniRef50_A7SFG6 Cluster: Predicted protein; n=4; Nematostella ve... 39 0.15 UniRef50_Q61KY4 Cluster: Putative uncharacterized protein CBG091... 31 0.16 UniRef50_Q8WSF8 Cluster: Soluble acetylcholine receptor; n=2; Ap... 38 0.27 UniRef50_Q0GQQ7 Cluster: PH-sensitive chloride channel variant 4... 38 0.27 UniRef50_Q7YTP9 Cluster: Putative uncharacterized protein; n=2; ... 38 0.36 UniRef50_P58154 Cluster: Acetylcholine-binding protein precursor... 38 0.36 UniRef50_UPI00015B58ED Cluster: PREDICTED: similar to GABA-gated... 38 0.47 UniRef50_Q4SXG4 Cluster: Chromosome undetermined SCAF12416, whol... 38 0.47 UniRef50_Q21420 Cluster: Putative uncharacterized protein; n=4; ... 38 0.47 UniRef50_A7RT31 Cluster: Predicted protein; n=1; Nematostella ve... 38 0.47 UniRef50_O01792 Cluster: Putative uncharacterized protein; n=2; ... 37 0.62 UniRef50_A7SCG0 Cluster: Predicted protein; n=1; Nematostella ve... 37 0.62 UniRef50_A7S5Y7 Cluster: Predicted protein; n=1; Nematostella ve... 37 0.82 UniRef50_Q61R47 Cluster: Putative uncharacterized protein CBG067... 36 1.1 UniRef50_Q5WN65 Cluster: Putative uncharacterized protein CBG081... 36 1.1 UniRef50_UPI0000DB7771 Cluster: PREDICTED: similar to nicotinic ... 36 1.4 UniRef50_Q3JT18 Cluster: Flavoprotein reductase; n=2; Burkholder... 36 1.9 UniRef50_UPI0000E4771F Cluster: PREDICTED: hypothetical protein;... 35 2.5 UniRef50_Q4SGK0 Cluster: Chromosome 3 SCAF14593, whole genome sh... 35 2.5 UniRef50_A7K8M5 Cluster: Putative uncharacterized protein z265L;... 35 2.5 UniRef50_P54246 Cluster: Acetylcholine receptor subunit alpha-ty... 35 2.5 UniRef50_UPI0001560B17 Cluster: PREDICTED: similar to precursor ... 35 3.3 UniRef50_UPI0000E81668 Cluster: PREDICTED: similar to Probable p... 35 3.3 UniRef50_UPI0000E46711 Cluster: PREDICTED: similar to Neuronal a... 35 3.3 UniRef50_Q9V9Y4 Cluster: CG11340-PA; n=2; Sophophora|Rep: CG1134... 35 3.3 UniRef50_P91985 Cluster: Putative uncharacterized protein; n=1; ... 35 3.3 UniRef50_UPI0000E46D49 Cluster: PREDICTED: similar to nicotinic ... 34 4.4 UniRef50_UPI000051DDF1 Cluster: ACETYLCHOLINE-BINDING PROTEIN; n... 34 5.8 UniRef50_UPI00015ADFAB Cluster: hypothetical protein NEMVEDRAFT_... 34 5.8 UniRef50_Q098H2 Cluster: Sensor protein; n=1; Stigmatella aurant... 34 5.8 UniRef50_A2Y2V1 Cluster: Putative uncharacterized protein; n=2; ... 34 5.8 UniRef50_A7RTF6 Cluster: Predicted protein; n=2; Nematostella ve... 34 5.8 UniRef50_Q4STL8 Cluster: Chromosome undetermined SCAF14147, whol... 33 7.7 UniRef50_A7NZ98 Cluster: Chromosome chr6 scaffold_3, whole genom... 33 7.7 UniRef50_Q9W4G1 Cluster: CG6927-PA; n=6; Diptera|Rep: CG6927-PA ... 33 7.7 UniRef50_Q9VUV2 Cluster: CG33989-PD, isoform D; n=2; Drosophila ... 33 7.7 UniRef50_Q9VDU9 Cluster: CG7411-PA; n=12; Endopterygota|Rep: CG7... 33 7.7 >UniRef50_UPI0000D55EDD Cluster: PREDICTED: similar to CG11822-PA, isoform A; n=1; Tribolium castaneum|Rep: PREDICTED: similar to CG11822-PA, isoform A - Tribolium castaneum Length = 438 Score = 84.6 bits (200), Expect = 3e-15 Identities = 46/159 (28%), Positives = 82/159 (51%), Gaps = 8/159 (5%) Frame = +2 Query: 92 NATSLSLMIDSLLATYDRDSPP-----DSKIVVNLTLHLRHANIRESESTVRIQADLQMN 256 N+T + LL YD+ + P +K+V LT+ RH + E +ST+ + + ++++ Sbjct: 36 NSTVTDKLRQDLLLNYDKFARPAQHYNTTKVVFGLTI--RHIELNEFKSTLVVHSWIRLS 93 Query: 257 WIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLLNAAATTAGDYA--LRARVSNNGSVSW 427 W D++L WN+ +G T ++ +W+PD+ L N+A ++ + + V G V W Sbjct: 94 WKDEKLQWNSTNYGGLETLNLADHEIWQPDIFLYNSATSSGITHYGNVNCIVYEGGDVLW 153 Query: 428 IKRLDISTPISMQLDSWPNDMQTCTFKFGSRMHNSDEMD 544 + S ++ L WP D Q C FGS +N D++D Sbjct: 154 VPPAQFSVLCNLNLKYWPFDTQRCEMIFGSWTYNGDQID 192 >UniRef50_Q2XWK6 Cluster: Nicotinic acetylcholine receptor subunit type G; n=1; Lymnaea stagnalis|Rep: Nicotinic acetylcholine receptor subunit type G - Lymnaea stagnalis (Great pond snail) Length = 618 Score = 75.4 bits (177), Expect = 2e-12 Identities = 48/153 (31%), Positives = 80/153 (52%), Gaps = 8/153 (5%) Frame = +2 Query: 110 LMIDSLLATYDRDSPP------DSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKR 271 L+++ LLA Y R S P ++ LTL ++ +++ E + I L+ W+D+R Sbjct: 90 LLMERLLARYHRYSRPVMNASLSVQVKFGLTL-VQISDMDEVNQVLTINVWLEQEWVDER 148 Query: 272 LSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAAT-TAGDYALRARVSNNGSVSWIKRLDI 445 L+W+ E+ L + E+LW PD+VL N+A T G +A V +NG+V W Sbjct: 149 LTWSPKEYNNLHILRIPCEKLWLPDIVLYNSADDYTTGYMNSKAMVQHNGTVFWPPPAKF 208 Query: 446 STPISMQLDSWPNDMQTCTFKFGSRMHNSDEMD 544 + + + +P D QTC KFGS ++ ++D Sbjct: 209 RSSCKIDITYFPFDDQTCELKFGSWTYDGFQVD 241 >UniRef50_A7RFJ5 Cluster: Predicted protein; n=2; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 328 Score = 75.4 bits (177), Expect = 2e-12 Identities = 47/158 (29%), Positives = 81/158 (51%), Gaps = 9/158 (5%) Frame = +2 Query: 110 LMIDSLLATYDRDSPP--DSKIVVNLTLHL-RHANIRESESTVRIQADLQMNWIDKRLSW 280 +++ L YDRD P ++ +VV L R A + E + V L+ W++ LSW Sbjct: 8 ILLRYLFTNYDRDIHPGGNNPVVVTFGAKLGRIAAVDEKNNVVLAHWYLKQKWVNPSLSW 67 Query: 281 NAGEWG-CSTWLVSSERLWRPDVVLLNAAATT---AGDYALRARVSN--NGSVSWIKRLD 442 NA E+G +T V +RLW PD+VL N A AG + + ++ +G++ W+ Sbjct: 68 NASEFGGVNTLHVEPDRLWVPDIVLYNNADPKNDLAGGFQYKTKIEMQADGTMIWLAPAM 127 Query: 443 ISTPISMQLDSWPNDMQTCTFKFGSRMHNSDEMDFVID 556 + M + +P D Q+C +F S M+++ +++ ID Sbjct: 128 FHSACPMDIRYFPFDEQSCDLQFASWMYDTSKLEMKID 165 >UniRef50_Q4S3I4 Cluster: Chromosome 1 SCAF14749, whole genome shotgun sequence; n=2; Euteleostomi|Rep: Chromosome 1 SCAF14749, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 503 Score = 74.5 bits (175), Expect = 3e-12 Identities = 41/124 (33%), Positives = 63/124 (50%), Gaps = 3/124 (2%) Frame = +2 Query: 203 NIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLL-NAAATTA 376 ++ E + L WID +L WN ++G T + V SE LW PD+VL NA Sbjct: 50 DVDEKNQLMTTNVWLCQEWIDYKLRWNPDKYGGITSIRVPSENLWLPDIVLYENADGRFE 109 Query: 377 GDYALRARVSNNGSVSWIKRLDISTPISMQLDSWPNDMQTCTFKFGSRMHNSDEMDFV-I 553 G +A V NG+++W + +M + +P D Q CT KFGS ++ +D + I Sbjct: 110 GSLMTKAIVRYNGAITWTPPASYKSACTMDVTFFPFDRQNCTMKFGSWTYDGTMVDLILI 169 Query: 554 DKRI 565 DK++ Sbjct: 170 DKQV 173 >UniRef50_Q4S3I6 Cluster: Chromosome 1 SCAF14749, whole genome shotgun sequence; n=1; Tetraodon nigroviridis|Rep: Chromosome 1 SCAF14749, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 340 Score = 72.9 bits (171), Expect = 1e-11 Identities = 50/170 (29%), Positives = 78/170 (45%), Gaps = 6/170 (3%) Frame = +2 Query: 62 CAIASAAECENATSLSLMIDSLLATYDRDSPPDSK---IVVNLTL-HLRHANIRESESTV 229 C AS AE E L+ R + +S+ I + ++L L H N R+ T Sbjct: 1 CTAASCAEVEERLVSHLLAPDRYNKLIRPAVNNSQQVTIYIQVSLAQLIHVNERDQIMTT 60 Query: 230 RIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARV 403 L W D RL WN E+ G + ++ +W PD+VL N A T Y A + Sbjct: 61 NCW--LSQVWYDYRLMWNPEEYEGIKKIRLPTQHIWLPDIVLYNNADGTYEVSYYSNAVI 118 Query: 404 SNNGSVSWIKRLDISTPISMQLDSWPNDMQTCTFKFGSRMHNSDEMDFVI 553 SNNG V+W+ + +++ +P D Q CT +F S ++ E+D ++ Sbjct: 119 SNNGEVNWLPPAIYKSACKIEVRDFPFDQQNCTLQFRSWTYDHTEIDLIL 168 >UniRef50_Q2XWK8 Cluster: Nicotinic acetylcholine receptor subunit type E; n=16; Protostomia|Rep: Nicotinic acetylcholine receptor subunit type E - Lymnaea stagnalis (Great pond snail) Length = 538 Score = 72.1 bits (169), Expect = 2e-11 Identities = 44/135 (32%), Positives = 70/135 (51%), Gaps = 6/135 (4%) Frame = +2 Query: 164 KIVVNLTLHLRHA-NIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWR 337 K+VV + + L +I E + L+ W DK+L+W A E+G L V SE +W Sbjct: 56 KLVVKMGIRLSQLIDIDEKNQIMTTNVWLRQEWTDKKLTWQASEYGGVDHLYVPSEHIWL 115 Query: 338 PDVVLLNAAATTAGDYAL----RARVSNNGSVSWIKRLDISTPISMQLDSWPNDMQTCTF 505 PD+VL N A G+Y + +A V + G V W + ++ ++ +P D Q+C Sbjct: 116 PDIVLYNNAD---GNYEVTLMTKATVHSTGLVVWEPPAIYKSSCTINVEFFPFDEQSCKM 172 Query: 506 KFGSRMHNSDEMDFV 550 KFGS ++ D++D V Sbjct: 173 KFGSWTYDGDQVDLV 187 >UniRef50_Q60KR8 Cluster: Putative uncharacterized protein CBG23934; n=1; Caenorhabditis briggsae|Rep: Putative uncharacterized protein CBG23934 - Caenorhabditis briggsae Length = 551 Score = 70.5 bits (165), Expect = 5e-11 Identities = 43/167 (25%), Positives = 81/167 (48%), Gaps = 8/167 (4%) Frame = +2 Query: 74 SAAECENATSLSLMIDSLLATYDRDS-PPDSK----IVVNLTLHLRH-ANIRESESTVRI 235 S + + T+ + ++LL+ Y+R + PP K + + L L ++ E + + + Sbjct: 10 SLFKLNDCTAYKNLFETLLSRYNRIAFPPGEKHNNSLKIEFKLRLDQIVDVHEKDQVITL 69 Query: 236 QADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAG-DYALRARVSN 409 + L W D RLSWN E+G T + E +W PD++L N A + + VS+ Sbjct: 70 KGILVHRWHDIRLSWNPQEFGDITLMHFPGEMIWLPDIILYNNAHGSPWVSETTQVHVSH 129 Query: 410 NGSVSWIKRLDISTPISMQLDSWPNDMQTCTFKFGSRMHNSDEMDFV 550 G V+W + ++ ++ +P D+Q C KFGS + +++ + Sbjct: 130 EGRVTWHPPVAYDAFCNIDIEWYPYDLQICELKFGSWTYGGSQLNLI 176 >UniRef50_P48182 Cluster: Acetylcholine receptor subunit beta-type acr-2 precursor; n=3; Rhabditida|Rep: Acetylcholine receptor subunit beta-type acr-2 precursor - Caenorhabditis elegans Length = 575 Score = 70.5 bits (165), Expect = 5e-11 Identities = 37/115 (32%), Positives = 59/115 (51%), Gaps = 2/115 (1%) Frame = +2 Query: 203 NIRESESTVRIQADLQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLLNAA-ATTA 376 N+ E ++ L M W D +L+WN E+G S V S+R+W PD+VL N A Sbjct: 99 NVDEKNQILQTNVWLTMKWNDFQLAWNPAEYGNISNLHVPSDRVWLPDIVLFNNADGNYE 158 Query: 377 GDYALRARVSNNGSVSWIKRLDISTPISMQLDSWPNDMQTCTFKFGSRMHNSDEM 541 + V ++G V+W+ + + ++ +P D Q CT FGS +NS+E+ Sbjct: 159 VSFKSNVFVDHHGDVTWVPPAMFKSSCRIDVEWFPFDEQCCTLVFGSWTYNSEEV 213 >UniRef50_Q17BK7 Cluster: Nicotinic acetylcholine receptor, beta-2 subunit, putative; n=1; Aedes aegypti|Rep: Nicotinic acetylcholine receptor, beta-2 subunit, putative - Aedes aegypti (Yellowfever mosquito) Length = 434 Score = 70.1 bits (164), Expect = 7e-11 Identities = 44/149 (29%), Positives = 73/149 (48%), Gaps = 8/149 (5%) Frame = +2 Query: 125 LLATYDRDSPP--DSKIVVNLTLHLRHANIRESESTVRIQADL--QMNWIDKRLSWNAGE 292 L +YD + P D K VN+++ + EST + A++ M WID+ L W++ E Sbjct: 41 LCNSYDANQRPVKDIKFAVNVSVLPVLMSFEYDESTNALNANMLVTMEWIDENLKWDSKE 100 Query: 293 WGCSTWL-VSSERLWRPDVVLLNAAA---TTAGDYALRARVSNNGSVSWIKRLDISTPIS 460 + T + +SS+++W PD L ++ T LR+ V +G+V + D S Sbjct: 101 YNNQTTIAISSDQIWTPDFQLYSSTVKFDTKQSCTNLRSLVKYDGTVIAVPTCDFSARCE 160 Query: 461 MQLDSWPNDMQTCTFKFGSRMHNSDEMDF 547 WP D Q C FG+ M ++ E+D+ Sbjct: 161 ADYTDWPLDTQRCRMLFGAWMEHAGEVDY 189 >UniRef50_UPI0000E49401 Cluster: PREDICTED: similar to alpha 10 subunit of nicotinic acetylcholine receptor; n=1; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to alpha 10 subunit of nicotinic acetylcholine receptor - Strongylocentrotus purpuratus Length = 347 Score = 68.5 bits (160), Expect = 2e-10 Identities = 32/105 (30%), Positives = 57/105 (54%), Gaps = 2/105 (1%) Frame = +2 Query: 242 DLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATT-AGDYALRARVSNNG 415 +LQ W D L WN ++G T + + S +W+PD++L N A ++ G A VSN+G Sbjct: 87 NLQFEWSDPNLKWNPDDYGGITKITIPSSNIWKPDILLYNNADSSFKGAMKTNAAVSNDG 146 Query: 416 SVSWIKRLDISTPISMQLDSWPNDMQTCTFKFGSRMHNSDEMDFV 550 V+W + + ++ +P D Q CT +FGS + ++ ++ + Sbjct: 147 IVTWFAPAIFRSSCKININYFPFDKQECTLQFGSWAYTTEHLNLL 191 >UniRef50_Q4S864 Cluster: Chromosome 5 SCAF14709, whole genome shotgun sequence; n=3; Tetraodontidae|Rep: Chromosome 5 SCAF14709, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 733 Score = 68.5 bits (160), Expect = 2e-10 Identities = 35/101 (34%), Positives = 54/101 (53%), Gaps = 2/101 (1%) Frame = +2 Query: 257 WIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGSVSWI 430 W D +L WN E+G ++ V S R+W+PD+VL N A D +A + NG V+WI Sbjct: 233 WNDYKLRWNPKEYGGVEYIRVPSSRIWKPDIVLYNNAVGDFQVDDKTKALLRYNGDVTWI 292 Query: 431 KRLDISTPISMQLDSWPNDMQTCTFKFGSRMHNSDEMDFVI 553 + + + +P D Q CT KFGS ++ ++D V+ Sbjct: 293 PPAIFKSSCKIDVTYFPFDYQNCTMKFGSWTYDKAKIDLVL 333 Score = 62.5 bits (145), Expect = 1e-08 Identities = 36/121 (29%), Positives = 59/121 (48%), Gaps = 3/121 (2%) Frame = +2 Query: 164 KIVVNLTLHLRHA-NIRESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWR 337 ++ V L + L ++ E E + L +W+D RLSW+ ++ G + + S +W Sbjct: 33 RVPVKLQVSLAQLISVNEREQIMTTNLWLMQHWVDYRLSWDPAKYEGINKLRIPSRLIWL 92 Query: 338 PDVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDSWPNDMQTCTFKFG 514 PD+VL N A T A V NGS++W+ + +++ +P D Q CT KF Sbjct: 93 PDIVLYNNADGTYEVTVYTNAIVLFNGSINWLPPAIYKSACKIEVKHFPFDQQNCTLKFR 152 Query: 515 S 517 S Sbjct: 153 S 153 >UniRef50_P30532 Cluster: Neuronal acetylcholine receptor subunit alpha-5 precursor; n=70; Euteleostomi|Rep: Neuronal acetylcholine receptor subunit alpha-5 precursor - Homo sapiens (Human) Length = 468 Score = 68.5 bits (160), Expect = 2e-10 Identities = 37/154 (24%), Positives = 74/154 (48%), Gaps = 6/154 (3%) Frame = +2 Query: 113 MIDSLLATYDRDSPP----DSKIVVNLTLHLRH-ANIRESESTVRIQADLQMNWIDKRLS 277 ++ L Y+R P + KI + L + ++ E + L+ WID +L Sbjct: 50 LLKDLFQDYERWVRPVEHLNDKIKIKFGLAISQLVDVDEKNQLMTTNVWLKQEWIDVKLR 109 Query: 278 WNAGEWG-CSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVSWIKRLDISTP 454 WN ++G V S+ +W PD+VL + A + + + NG+V+W + + Sbjct: 110 WNPDDYGGIKVIRVPSDSVWTPDIVLFDNADGRFEGTSTKTVIRYNGTVTWTPPANYKSS 169 Query: 455 ISMQLDSWPNDMQTCTFKFGSRMHNSDEMDFVID 556 ++ + +P D+Q C+ KFGS ++ ++D +++ Sbjct: 170 CTIDVTFFPFDLQNCSMKFGSWTYDGSQVDIILE 203 >UniRef50_UPI00015A3E3C Cluster: Neuronal acetylcholine receptor subunit alpha-4 precursor.; n=1; Danio rerio|Rep: Neuronal acetylcholine receptor subunit alpha-4 precursor. - Danio rerio Length = 556 Score = 68.1 bits (159), Expect = 3e-10 Identities = 43/165 (26%), Positives = 83/165 (50%), Gaps = 10/165 (6%) Frame = +2 Query: 86 CENATSLSLMIDSLLATYDRDSPPDSKI--VVNLTLHLRHA---NIRESESTVRIQADLQ 250 C+ + +++SLL+ Y + + P + VV++ L A ++ E + ++ Sbjct: 24 CDEVQAEERLLNSLLSAYSKLTRPVHSVSDVVHVHFGLSIAQLIDVDEKNQMMTTNVWVK 83 Query: 251 MNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNG 415 W+D RL W + G S+ + ++ +W+PD+VL N A GD+ + +A + ++G Sbjct: 84 QEWLDYRLRWTPEDNGNVSSMRIPAQFIWKPDIVLYNNAD---GDFTVTHLTKAHLLHDG 140 Query: 416 SVSWIKRLDISTPISMQLDSWPNDMQTCTFKFGSRMHNSDEMDFV 550 V+WI + S+ + P D Q CT KFGS ++ ++D + Sbjct: 141 RVTWIPPAIYKSSCSIDVTFLPFDQQNCTIKFGSWTYDRSKIDLI 185 >UniRef50_Q5BW84 Cluster: SJCHGC08361 protein; n=1; Schistosoma japonicum|Rep: SJCHGC08361 protein - Schistosoma japonicum (Blood fluke) Length = 213 Score = 67.3 bits (157), Expect = 5e-10 Identities = 39/152 (25%), Positives = 72/152 (47%), Gaps = 8/152 (5%) Frame = +2 Query: 116 IDSLLATYDRDSPP----DSKIVVNLTLHLRH-ANIRESESTVRIQADLQMNWIDKRLSW 280 ID+L+ Y+ P K+ V +++ L+ + E + L+ W D L W Sbjct: 16 IDTLMKNYESSVRPLKNISEKLTVKISIRLQQIGGLNERNQVLTTILFLEQIWEDDYLKW 75 Query: 281 NAGEWG-CSTWLVSSERLWRPDVVLLNAAATTAGDY--ALRARVSNNGSVSWIKRLDIST 451 N E+G T + ++++W PD + N A T + + + ++G VSW + + T Sbjct: 76 NESEFGNVRTLRIPAKQVWTPDTYVFNNADHTNSGFLEGIYVIIHSSGKVSWPIPVQLKT 135 Query: 452 PISMQLDSWPNDMQTCTFKFGSRMHNSDEMDF 547 + + +P D Q C +FGS M+ SD +++ Sbjct: 136 SCKVDITLFPFDHQNCEIQFGSWMYKSDWIEY 167 >UniRef50_Q2XWL1 Cluster: Nicotinic acetylcholine receptor subunit type B; n=1; Lymnaea stagnalis|Rep: Nicotinic acetylcholine receptor subunit type B - Lymnaea stagnalis (Great pond snail) Length = 527 Score = 67.3 bits (157), Expect = 5e-10 Identities = 34/99 (34%), Positives = 56/99 (56%), Gaps = 2/99 (2%) Frame = +2 Query: 254 NWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLLNAAATTAGDYALRARV-SNNGSVSW 427 +WID L+WN E+G +T V+++ +W+PD+ L N A T + V S+NG V W Sbjct: 88 SWIDMYLAWNESEYGNITTVRVNNDDIWKPDIKLYNYADTRLEEKREALCVLSSNGEVVW 147 Query: 428 IKRLDISTPISMQLDSWPNDMQTCTFKFGSRMHNSDEMD 544 I + + S+ + +P D+Q C KFGS ++ ++D Sbjct: 148 IPQAVFKSSCSIDIRHFPFDVQRCDMKFGSWTYDGSKLD 186 >UniRef50_A0EIZ7 Cluster: Nicotinic acetylcholine receptor alpha9 subunit; n=1; Apis mellifera|Rep: Nicotinic acetylcholine receptor alpha9 subunit - Apis mellifera (Honeybee) Length = 431 Score = 67.3 bits (157), Expect = 5e-10 Identities = 44/170 (25%), Positives = 80/170 (47%), Gaps = 8/170 (4%) Frame = +2 Query: 89 ENATSLSLMIDSLLATYDRDSPPDS--KIVVNLTLHL--RHANIRESESTVRIQADLQMN 256 ++ T+L + L YD + P S +I N+T+ L + + S + + + + + Sbjct: 39 DHPTTLLKLKRYLFCEYDPNVRPISSHQIANNVTMQLLPKLMEFDDWTSVMELHSWMTLM 98 Query: 257 WIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATT---AGDYALRARVSNNGSVS 424 W D LSW ++ G + V S+ +W PD+ + N+ T G V ++GSVS Sbjct: 99 WTDSHLSWKPSDFDGINYIYVKSDDIWVPDISVYNSGDMTFDQTGIPPTTCLVFSSGSVS 158 Query: 425 WIKRLDISTPISMQLDSWPNDMQTCTFKFGSRMHNSDEMDFVIDKRIYSM 574 + + + SWP D C FGS +H+ +E++ +DK+ + M Sbjct: 159 CVPSVKHVAKCATDFSSWPYDTHRCRINFGSWVHSGEEVNIFLDKKGFHM 208 >UniRef50_Q9N4M3 Cluster: Acetylcholine receptor protein 6; n=1; Caenorhabditis elegans|Rep: Acetylcholine receptor protein 6 - Caenorhabditis elegans Length = 562 Score = 66.9 bits (156), Expect = 7e-10 Identities = 33/118 (27%), Positives = 60/118 (50%), Gaps = 2/118 (1%) Frame = +2 Query: 203 NIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLL-NAAATTA 376 ++ E + + ++ L +W+D RLSWN E+G T + E LW PD++L NA + Sbjct: 44 DVHEKDQVITLKGTLIHHWLDYRLSWNPDEFGNITLMHFPGEMLWLPDIILYNNAHGSPW 103 Query: 377 GDYALRARVSNNGSVSWIKRLDISTPISMQLDSWPNDMQTCTFKFGSRMHNSDEMDFV 550 + VS G V+W + ++ ++ +P D+Q C KFGS + +++ + Sbjct: 104 VSETTQVHVSFEGRVTWQPPVVYDAFCNIDIEWYPYDLQICELKFGSWTYGGSQLNLI 161 >UniRef50_P91766 Cluster: Acetylcholine receptor subunit alpha-like precursor; n=31; Coelomata|Rep: Acetylcholine receptor subunit alpha-like precursor - Manduca sexta (Tobacco hawkmoth) (Tobacco hornworm) Length = 516 Score = 66.9 bits (156), Expect = 7e-10 Identities = 44/165 (26%), Positives = 75/165 (45%), Gaps = 9/165 (5%) Frame = +2 Query: 77 AAECENATSLSLMIDSLLATYDRDSPPDSKIVVNLTLHLR-------HANIRESESTVRI 235 A C + D LL+ Y++ P + LT+ ++ N++ T + Sbjct: 16 ATGCAGNPDAKRLYDDLLSNYNKLVRPVLNVSDALTVRIKLKLSQLIDVNLKNQIMTTNL 75 Query: 236 QADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAA-ATTAGDYALRARVSN 409 ++ +W D +LSW E+G L V S+ +WRPD+VL N A A +A ++ Sbjct: 76 W--VEQSWYDYKLSWEPREYGGVEMLHVPSDHIWRPDIVLYNNADGNFEVTLATKATLNY 133 Query: 410 NGSVSWIKRLDISTPISMQLDSWPNDMQTCTFKFGSRMHNSDEMD 544 G V W + + ++ +P D QTC KFGS ++ ++D Sbjct: 134 TGRVEWRPPAIYKSSCEIDVEYFPFDQQTCVMKFGSWTYDGFQVD 178 >UniRef50_UPI0001560C7D Cluster: PREDICTED: similar to cholinergic receptor, nicotinic, alpha 2 (neuronal); n=2; Laurasiatheria|Rep: PREDICTED: similar to cholinergic receptor, nicotinic, alpha 2 (neuronal) - Equus caballus Length = 630 Score = 66.5 bits (155), Expect = 9e-10 Identities = 42/140 (30%), Positives = 67/140 (47%), Gaps = 4/140 (2%) Frame = +2 Query: 137 YDRDSPPDSKIV-VNLTLHLRHA-NIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTW 310 Y R P S +V V L + ++ E + L+ W D +L WN ++G T Sbjct: 71 YARPVPNTSDVVIVRFGLSIAQLIDVDEKNQMMTTNVWLKQEWSDYKLRWNPADFGNITS 130 Query: 311 L-VSSERLWRPDVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDSWPN 484 L V SE +W PD+VL N A A + +A + + G+V W+ + S+ + +P Sbjct: 131 LRVPSEMIWIPDIVLYNNADGEFAVTHMTKAHLFSTGTVHWVPPAIYKSSCSIDVTFFPF 190 Query: 485 DMQTCTFKFGSRMHNSDEMD 544 D Q C KFGS ++ ++D Sbjct: 191 DQQNCKMKFGSWTYDKAKID 210 >UniRef50_UPI00015B4A35 Cluster: PREDICTED: similar to nicotinic acetylcholine receptor alpha9 subunit; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to nicotinic acetylcholine receptor alpha9 subunit - Nasonia vitripennis Length = 431 Score = 66.1 bits (154), Expect = 1e-09 Identities = 41/149 (27%), Positives = 65/149 (43%), Gaps = 8/149 (5%) Frame = +2 Query: 125 LLATYDRDSPP--DSKIVVNLTLHLRHA--NIRESESTVRIQADLQMNWIDKRLSWNAGE 292 L YD P VN+++ +R N + +ST + A + W D+ L+W + Sbjct: 39 LFCEYDTSIRPVLSKNTAVNVSVVIRPMLMNFIDDKSTFILHAWISFEWTDQHLTWKPED 98 Query: 293 W-GCSTWLVSSERLWRPDVVLLNAA---ATTAGDYALRARVSNNGSVSWIKRLDISTPIS 460 + G V S+ +W PD L N+ + G ++S+ GSV + + T Sbjct: 99 FDGVQETRVKSDEIWVPDFALYNSGDMETSQTGIPETLCQLSHTGSVICLPSIKYKTLCE 158 Query: 461 MQLDSWPNDMQTCTFKFGSRMHNSDEMDF 547 WP D QTCT + GS H +E+ F Sbjct: 159 SDFTYWPYDKQTCTLRMGSWTHTGEEISF 187 >UniRef50_Q93329 Cluster: Putative uncharacterized protein lev-8; n=2; Caenorhabditis|Rep: Putative uncharacterized protein lev-8 - Caenorhabditis elegans Length = 531 Score = 66.1 bits (154), Expect = 1e-09 Identities = 40/154 (25%), Positives = 75/154 (48%), Gaps = 7/154 (4%) Frame = +2 Query: 104 LSLMIDSLLATYDRDSPP----DSKIVVNLTLHL-RHANIRESESTVRIQADLQMNWIDK 268 +S ++++LL Y++ P + V +L R ++ E + L+M W DK Sbjct: 29 VSQLLENLLTDYNKAVRPVHNASDALKVKFGANLCRLIDVDEVNQVLTTSLWLEMQWYDK 88 Query: 269 RLSWNAGEWGCSTWL-VSSERLWRPDVVLL-NAAATTAGDYALRARVSNNGSVSWIKRLD 442 +L+WN +WG ++ + S+++W PD+VL NA A++ ++G V W Sbjct: 89 KLTWNPTDWGGVEYIHIPSDQIWIPDIVLYNNADGEPHITITSLAKIDHHGRVVWQPPSI 148 Query: 443 ISTPISMQLDSWPNDMQTCTFKFGSRMHNSDEMD 544 + + + +P D QTC KFG ++ + +D Sbjct: 149 YKSFCPINIKYFPYDWQTCEMKFGGWSNDGETLD 182 >UniRef50_Q27218 Cluster: Acetylcholine receptor subunit beta-type lev-1 precursor; n=6; Caenorhabditis|Rep: Acetylcholine receptor subunit beta-type lev-1 precursor - Caenorhabditis elegans Length = 507 Score = 66.1 bits (154), Expect = 1e-09 Identities = 37/135 (27%), Positives = 67/135 (49%), Gaps = 5/135 (3%) Frame = +2 Query: 203 NIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAA-ATTA 376 N+ E E + L M W D +L W+ ++ T + V+ E++W PD+VL N A Sbjct: 77 NVDEKEQVMHTNVWLTMKWDDFQLKWDPRDYANITQIRVAPEKVWLPDIVLFNNADGNYE 136 Query: 377 GDYALRARVSNNGSVSWIKRLDISTPISMQLDSWPNDMQTCTFKFGSRMHNSDE--MDFV 550 + + + G+V W+ + + ++ +P D Q C+ FGS +N DE +DF+ Sbjct: 137 VSFMCNVLILSTGTVLWVPPAIYKSSCIIDVEFFPFDDQLCSLTFGSWTYNRDEIKLDFL 196 Query: 551 IDKRI-YSMFESGSV 592 R+ +S + + S+ Sbjct: 197 TSDRVDFSEYSTSSI 211 >UniRef50_P17644 Cluster: Acetylcholine receptor subunit alpha-like 2 precursor; n=38; Neoptera|Rep: Acetylcholine receptor subunit alpha-like 2 precursor - Drosophila melanogaster (Fruit fly) Length = 576 Score = 66.1 bits (154), Expect = 1e-09 Identities = 48/156 (30%), Positives = 75/156 (48%), Gaps = 12/156 (7%) Frame = +2 Query: 113 MIDSLLATYDRDSPPDSK----IVVNLTLHLRHA---NIRESESTVRIQADLQMNWIDKR 271 + D LL+ Y+R P S ++V L L L N+++ T + L+ W D + Sbjct: 48 LYDDLLSNYNRLIRPVSNNTDTVLVKLGLRLSQLIDLNLKDQILTTNVW--LEHEWQDHK 105 Query: 272 LSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNGSVSWIKR 436 W+ E+G T L V SE +W PD+VL N A G+Y + +A + G V W Sbjct: 106 FKWDPSEYGGVTELYVPSEHIWLPDIVLYNNAD---GEYVVTTMTKAILHYTGKVVWTPP 162 Query: 437 LDISTPISMQLDSWPNDMQTCTFKFGSRMHNSDEMD 544 + + + +P D QTC KFGS ++ D++D Sbjct: 163 AIFKSSCEIDVRYFPFDQQTCFMKFGSWTYDGDQID 198 >UniRef50_A7S3F7 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 334 Score = 65.7 bits (153), Expect = 2e-09 Identities = 42/143 (29%), Positives = 72/143 (50%), Gaps = 8/143 (5%) Frame = +2 Query: 113 MIDSLLATYDRDSPP---DSKIV-VNLTLHLRHA-NIRESESTVRIQADLQMNWIDKRLS 277 +I LL TY+ + P D+ V + LT+ L+ ++ E ++ L+ W D RL+ Sbjct: 7 LIHDLLDTYNPRARPVTNDNHTVGLKLTIRLQQIMDVDEKNEVIQTFLILEQMWNDTRLA 66 Query: 278 WNAGEWG-CSTWLVSSERLWRPDVVLLNAAATTAG--DYALRARVSNNGSVSWIKRLDIS 448 WN E+G + S+ +W PD+ +LN+A + +R +++ G V W+ L + Sbjct: 67 WNETEYGGIKQMTLRSKLIWTPDISVLNSANKDMDLREKNIRLFINSAGEVLWMNPLILH 126 Query: 449 TPISMQLDSWPNDMQTCTFKFGS 517 T M + +P D Q C +FGS Sbjct: 127 TSCGMDIAHFPFDNQACELRFGS 149 >UniRef50_Q7T2R4 Cluster: Nicotinic acetylcholine receptor alpha 9d subunit; n=7; Clupeocephala|Rep: Nicotinic acetylcholine receptor alpha 9d subunit - Fugu rubripes (Japanese pufferfish) (Takifugu rubripes) Length = 521 Score = 64.9 bits (151), Expect = 3e-09 Identities = 42/152 (27%), Positives = 74/152 (48%), Gaps = 7/152 (4%) Frame = +2 Query: 110 LMIDSLLATYDRDSPP--DSKIVVNLTLHLRHANIRESESTVRIQAD---LQMNWIDKRL 274 LM D L + Y P D+ ++N+TL + + I + + +I ++ W+D L Sbjct: 12 LMTD-LFSNYTNALRPVEDTDHIINVTLQITLSQIIDMDERNQILTTYLWVRQVWMDAYL 70 Query: 275 SWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATT-AGDYALRARVSNNGSVSWIKRLDIS 448 +W ++ G T + S +WRPD+VL N+A + + ++G V W + Sbjct: 71 TWKKEDYDGLDTIRIPSSYVWRPDIVLYNSADDEFSSSMETNVVLRHDGQVMWDQPAITK 130 Query: 449 TPISMQLDSWPNDMQTCTFKFGSRMHNSDEMD 544 + S+ + +P D+Q C FGS HN ++MD Sbjct: 131 SSCSVDVAHFPFDLQECHLTFGSWTHNGNQMD 162 >UniRef50_Q15822 Cluster: Neuronal acetylcholine receptor subunit alpha-2 precursor; n=98; Euteleostomi|Rep: Neuronal acetylcholine receptor subunit alpha-2 precursor - Homo sapiens (Human) Length = 529 Score = 64.9 bits (151), Expect = 3e-09 Identities = 35/116 (30%), Positives = 58/116 (50%), Gaps = 2/116 (1%) Frame = +2 Query: 203 NIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAA-ATTA 376 ++ E + L+ W D +L WN ++G T L V SE +W PD+VL N A A Sbjct: 97 DVDEKNQMMTTNVWLKQEWSDYKLRWNPADFGNITSLRVPSEMIWIPDIVLYNNADGEFA 156 Query: 377 GDYALRARVSNNGSVSWIKRLDISTPISMQLDSWPNDMQTCTFKFGSRMHNSDEMD 544 + +A + + G+V W+ + S+ + +P D Q C KFGS ++ ++D Sbjct: 157 VTHMTKAHLFSTGTVHWVPPAIYKSSCSIDVTFFPFDQQNCKMKFGSWTYDKAKID 212 >UniRef50_UPI00015B5C4C Cluster: PREDICTED: similar to GABA-gated ion channel; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to GABA-gated ion channel - Nasonia vitripennis Length = 442 Score = 64.5 bits (150), Expect = 4e-09 Identities = 41/152 (26%), Positives = 71/152 (46%), Gaps = 7/152 (4%) Frame = +2 Query: 83 ECENATSLSLMIDSLLATYDRDSPPD---SKIVVNLTLHLRHAN-IRESESTVRIQADLQ 250 + N ++S ++D+LL YD P+ VV + + +R I E + T + + Sbjct: 43 QSNNHGNISELLDNLLRGYDNSVRPNFGGPPAVVEVDIMVRSMGPISEVDMTYSMDCYFR 102 Query: 251 MNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAAT---TAGDYALRARVSNNGSV 421 +W+D+RL++ +G+ + + R+W+PD N + T R+ +G V Sbjct: 103 QSWVDRRLAFQSGKETLALSISMLARIWKPDTYFYNGKQSYLHTITSPNKFVRLYQDGRV 162 Query: 422 SWIKRLDISTPISMQLDSWPNDMQTCTFKFGS 517 + RL I M L+ +P D Q C KFGS Sbjct: 163 LYSSRLTIKAACPMNLEDFPMDTQRCPLKFGS 194 >UniRef50_UPI0000EBE733 Cluster: PREDICTED: similar to nicotinic acetylcholine receptor alpha6 subunit; n=2; Bos taurus|Rep: PREDICTED: similar to nicotinic acetylcholine receptor alpha6 subunit - Bos taurus Length = 630 Score = 64.5 bits (150), Expect = 4e-09 Identities = 42/166 (25%), Positives = 77/166 (46%), Gaps = 10/166 (6%) Frame = +2 Query: 86 CENATSLSLMIDSLLATYDRDSPPDSKIVVNLTLHL-----RHANIRESESTVRIQADLQ 250 C S + L A Y++ P + +T++ + A++ E + L+ Sbjct: 33 CAGCASEERLFHKLFAHYNQFIRPVENVSDPITVYFEVAITQLADVDEVNQIMETNLWLR 92 Query: 251 MNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRAR----VSNNG 415 W D +L W+ E+ G T V +E +W+PD+VL N A GD+ ++ + + +G Sbjct: 93 HIWNDYKLRWDPTEYDGIETLRVPAEMIWKPDIVLYNNAV---GDFQVKGKTKALLKYDG 149 Query: 416 SVSWIKRLDISTPISMQLDSWPNDMQTCTFKFGSRMHNSDEMDFVI 553 ++W + M + +P D Q C+ KFGS ++ E+D +I Sbjct: 150 MITWTPPAIFKSSCPMDITFFPFDHQNCSLKFGSWTYDKAEIDLLI 195 >UniRef50_O44497 Cluster: Putative uncharacterized protein; n=2; Caenorhabditis|Rep: Putative uncharacterized protein - Caenorhabditis elegans Length = 445 Score = 64.5 bits (150), Expect = 4e-09 Identities = 34/151 (22%), Positives = 66/151 (43%), Gaps = 2/151 (1%) Frame = +2 Query: 74 SAAECENATSLSLMIDSLLATYDRDSPPDSKIVVNLTLHLRHANIRESESTVRIQADLQM 253 S C+ + + TY + +K+V ++ + + I E V++ + Sbjct: 54 SCHSCQGGDRAWKLRTHIQTTYQNATDNKTKVVRVESVRINNVEIDERRQNVKVFGRFVL 113 Query: 254 NWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATT-AGDYALRARVSN-NGSVSW 427 +W D +SW+ +WG S ++W P++V +N +T+ G + +N G + Sbjct: 114 SWNDTMVSWDKEQWGLSWLNFYWIQIWTPNIVQINGGSTSNPGQVTSKVLAANYTGQIYL 173 Query: 428 IKRLDISTPISMQLDSWPNDMQTCTFKFGSR 520 +TP Q + +PNDMQ +KF + Sbjct: 174 WSDFSFTTPFRFQYEDYPNDMQRVCYKFDDK 204 >UniRef50_Q24352 Cluster: Gamma-aminobutyric acid receptor alpha-like precursor (GABA(A) receptor alpha-like and glycine receptor-like subunit of Drosophila); n=3; Diptera|Rep: Gamma-aminobutyric acid receptor alpha-like precursor (GABA(A) receptor alpha-like and glycine receptor-like subunit of Drosophila) - Drosophila melanogaster (Fruit fly) Length = 686 Score = 64.5 bits (150), Expect = 4e-09 Identities = 41/152 (26%), Positives = 68/152 (44%), Gaps = 7/152 (4%) Frame = +2 Query: 83 ECENATSLSLMIDSLLATYDRDSPPD---SKIVVNLTLHLRHAN-IRESESTVRIQADLQ 250 + N ++S ++D+LL YD PD + + + +R I E + T + + Sbjct: 102 QSNNHANISELLDNLLRGYDNSIRPDFGGPPATIEVDIMVRSMGPISEVDMTYSMDCYFR 161 Query: 251 MNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAAT---TAGDYALRARVSNNGSV 421 +W+DKRL++ + + + R+W+PD N + T R+ NG V Sbjct: 162 QSWVDKRLAFEGAQDTLALSVSMLARIWKPDTYFYNGKQSYLHTITTPNKFVRIYQNGRV 221 Query: 422 SWIKRLDISTPISMQLDSWPNDMQTCTFKFGS 517 + RL I M L +P D+Q C KFGS Sbjct: 222 LYSSRLTIKAGCPMNLADFPMDIQKCPLKFGS 253 >UniRef50_P11230 Cluster: Acetylcholine receptor subunit beta precursor; n=30; Gnathostomata|Rep: Acetylcholine receptor subunit beta precursor - Homo sapiens (Human) Length = 501 Score = 64.5 bits (150), Expect = 4e-09 Identities = 45/130 (34%), Positives = 68/130 (52%), Gaps = 4/130 (3%) Frame = +2 Query: 164 KIVVNLTL-HLRHANIRESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWR 337 ++ V L L L N ++ E + ++ DL+ W D RLSW+ E G + +++E +W Sbjct: 53 RVSVGLILAQLISLNEKDEEMSTKVYLDLE--WTDYRLSWDPAEHDGIDSLRITAESVWL 110 Query: 338 PDVVLLNAAATTAGDYAL--RARVSNNGSVSWIKRLDISTPISMQLDSWPNDMQTCTFKF 511 PDVVLLN D AL VS++GSV W + S+Q+ +P D Q CT F Sbjct: 111 PDVVLLNNNDGNF-DVALDISVVVSSDGSVRWQPPGIYRSSCSIQVTYFPFDWQNCTMVF 169 Query: 512 GSRMHNSDEM 541 S ++S E+ Sbjct: 170 SSYSYDSSEV 179 >UniRef50_UPI00015B4DDF Cluster: PREDICTED: similar to neurotransmitter gated ion channel; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to neurotransmitter gated ion channel - Nasonia vitripennis Length = 461 Score = 64.1 bits (149), Expect = 5e-09 Identities = 40/156 (25%), Positives = 70/156 (44%), Gaps = 5/156 (3%) Frame = +2 Query: 92 NATSLSLMIDSLLATYDRDSPPD---SKIVVNLTLHLRHANIRESESTVRIQADLQMNWI 262 N T + LLA YD+ + P + V++ L+++ + + + + + M W Sbjct: 38 NETWTDRLKQHLLAKYDKFARPAQHWNTTTVSVKLNVQTVEVDDMTNVMAANVWVVMTWN 97 Query: 263 DKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALR-ARVSNNGSVSWIKR 436 D +L+WN+ E+ G + + +W PD+ LLN+AA Y R VS G V W+ Sbjct: 98 DDKLTWNSSEYSGLKQVNLGAHEIWLPDIYLLNSAAHGMEYYGDRHCVVSEQGVVLWVTP 157 Query: 437 LDISTPISMQLDSWPNDMQTCTFKFGSRMHNSDEMD 544 + WP +M TC S ++ ++D Sbjct: 158 TIFHGYCHLDFTFWPFEMNTCRLSLSSWTYDGTQVD 193 >UniRef50_UPI0000E47C59 Cluster: PREDICTED: similar to alpha-9 nicotinic acetylcholine receptor subunit precursor; n=1; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to alpha-9 nicotinic acetylcholine receptor subunit precursor - Strongylocentrotus purpuratus Length = 451 Score = 64.1 bits (149), Expect = 5e-09 Identities = 36/99 (36%), Positives = 53/99 (53%), Gaps = 3/99 (3%) Frame = +2 Query: 254 NWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYALRARV--SNNGSVS 424 NW D+ + W+ +G T L ++SE +W PDVVL N AA D+ V +N G V+ Sbjct: 42 NWKDEFMMWDPAVYGNITDLKIASELVWMPDVVLYNNAAKEYKDFMKDEIVVITNEGQVN 101 Query: 425 WIKRLDISTPISMQLDSWPNDMQTCTFKFGSRMHNSDEM 541 W IS+ S+ ++++P D Q C KFG H E+ Sbjct: 102 WAAPKIISSYCSINVNTFPFDEQQCPMKFGPWQHEGKEL 140 >UniRef50_Q4RRI3 Cluster: Chromosome 16 SCAF15002, whole genome shotgun sequence; n=3; Euteleostomi|Rep: Chromosome 16 SCAF15002, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 636 Score = 64.1 bits (149), Expect = 5e-09 Identities = 38/153 (24%), Positives = 72/153 (47%), Gaps = 7/153 (4%) Frame = +2 Query: 113 MIDSLLATYDRDSPP--DSKIVVNLTLHLRHANIRESESTVRIQAD---LQMNWIDKRLS 277 ++ L + Y P D+ ++N+TL + + I + + +I ++ W+D L Sbjct: 13 LLTDLFSNYTSALRPVEDTHNILNVTLQVTLSQIIDMDERNQILTAYLWIRRVWVDAHLK 72 Query: 278 WNAGEW-GCSTWLVSSERLWRPDVVLLNAAATT-AGDYALRARVSNNGSVSWIKRLDIST 451 WN E+ G T + S +WRPD+VL N A G + ++G ++W + Sbjct: 73 WNKDEYDGLDTIRIPSSYVWRPDIVLYNNADDHFTGPMDTNVVIRHDGQITWDSPAITKS 132 Query: 452 PISMQLDSWPNDMQTCTFKFGSRMHNSDEMDFV 550 + + +P D Q C F +GS +N +++D + Sbjct: 133 SCRVDVSFFPFDAQQCRFTYGSWTYNGNQLDIL 165 >UniRef50_Q2XWK3 Cluster: Nicotinic acetylcholine receptor subunit type K; n=1; Lymnaea stagnalis|Rep: Nicotinic acetylcholine receptor subunit type K - Lymnaea stagnalis (Great pond snail) Length = 501 Score = 64.1 bits (149), Expect = 5e-09 Identities = 39/148 (26%), Positives = 69/148 (46%), Gaps = 3/148 (2%) Frame = +2 Query: 158 DSKIVVNLTLHL-RHANIRESESTVRIQADLQMNWIDKRLSWNAGEWG-CSTWLVSSERL 331 + I +N + L + ++ E + + + W D L+WN + G V S ++ Sbjct: 53 NDSITINFNMQLIQIMDLDEKNQVLTLNVWDRYIWHDLHLTWNETKHGGVKNIRVPSNKI 112 Query: 332 WRPDVVLLNAAATTAGDYA-LRARVSNNGSVSWIKRLDISTPISMQLDSWPNDMQTCTFK 508 W PD+ L N A + R V +NG V W+ + + + + ++P D+Q CT K Sbjct: 113 WIPDLKLYNYADERLAERRDARCVVESNGKVLWMPQAIYKSSCEIDVATFPFDIQNCTLK 172 Query: 509 FGSRMHNSDEMDFVIDKRIYSMFESGSV 592 FGS HN + +D ++ E+GS+ Sbjct: 173 FGSWTHNGNLIDLMVLSMDGETGENGSI 200 >UniRef50_Q04844 Cluster: Acetylcholine receptor subunit epsilon precursor; n=35; Euteleostomi|Rep: Acetylcholine receptor subunit epsilon precursor - Homo sapiens (Human) Length = 493 Score = 64.1 bits (149), Expect = 5e-09 Identities = 36/134 (26%), Positives = 71/134 (52%), Gaps = 3/134 (2%) Frame = +2 Query: 155 PDSKIVVNLTLHLRHA-NIRESESTVRIQADLQMNWIDKRLSWNAGEWG-CSTWLVSSER 328 P+ + ++L + L + ++ E E T+ + ++W D RL+++ ++G T V SE Sbjct: 45 PEDTVTISLKVTLTNLISLNEKEETLTTSVWIGIDWQDYRLNYSKDDFGGIETLRVPSEL 104 Query: 329 LWRPDVVLLNAAATTAG-DYALRARVSNNGSVSWIKRLDISTPISMQLDSWPNDMQTCTF 505 +W P++VL N G Y V GSV+W+ + ++++ +P D Q C+ Sbjct: 105 VWLPEIVLENNIDGQFGVAYDANVLVYEGGSVTWLPPAIYRSVCAVEVTYFPFDWQNCSL 164 Query: 506 KFGSRMHNSDEMDF 547 F S+ +N++E++F Sbjct: 165 IFRSQTYNAEEVEF 178 >UniRef50_UPI0000E47D8F Cluster: PREDICTED: similar to nicotinic acetylcholine receptor alpha 7c subunit; n=1; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to nicotinic acetylcholine receptor alpha 7c subunit - Strongylocentrotus purpuratus Length = 257 Score = 63.7 bits (148), Expect = 6e-09 Identities = 34/113 (30%), Positives = 59/113 (52%), Gaps = 2/113 (1%) Frame = +2 Query: 212 ESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLL-NAAATTAGDY 385 E E + I ++ W D+ L W+ + G + VS +++W PD+ L N + Sbjct: 19 EMEQRITINGWRKLQWRDEFLGWDKETYDGIDSLEVSPDKIWLPDIKLYENIDKDFQSED 78 Query: 386 ALRARVSNNGSVSWIKRLDISTPISMQLDSWPNDMQTCTFKFGSRMHNSDEMD 544 A+ A V+N+G V+W + IS+ + + +P D+QTCT FGS + D ++ Sbjct: 79 AVNALVTNDGMVTWYTPMVISSSCKINVRYFPFDVQTCTLTFGSWAYTIDSLN 131 >UniRef50_Q66T35 Cluster: Nicotinic acetylcholine receptor subunit alpha 3; n=7; Coelomata|Rep: Nicotinic acetylcholine receptor subunit alpha 3 - Anopheles gambiae (African malaria mosquito) Length = 710 Score = 63.7 bits (148), Expect = 6e-09 Identities = 43/167 (25%), Positives = 74/167 (44%), Gaps = 9/167 (5%) Frame = +2 Query: 71 ASAAECENATSLSLMIDSLLATYDRDSPPDSKIVVNLTLHLR-------HANIRESESTV 229 A + C + D LL+ Y++ P + LT+ ++ N++ T Sbjct: 13 AVVSVCGGNPDAKRLYDDLLSNYNKLVRPVVNVTDALTVKIKLKLSQLIDVNLKNQIMTT 72 Query: 230 RIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAA-ATTAGDYALRARV 403 + ++ W D +L W E+G L V S+ +WRPD+VL N A A +A + Sbjct: 73 NLW--VEQTWYDYKLKWEPKEYGGVEMLHVPSDHIWRPDIVLYNNADGNFEVTLATKATL 130 Query: 404 SNNGSVSWIKRLDISTPISMQLDSWPNDMQTCTFKFGSRMHNSDEMD 544 + G V W + + ++ +P D QTC KFGS ++ ++D Sbjct: 131 NYTGRVEWRPPAIYKSSCEIDVEYFPFDEQTCVMKFGSWTYDGFQVD 177 >UniRef50_P48180 Cluster: Acetylcholine receptor subunit alpha-type acr-16 precursor; n=3; Caenorhabditis|Rep: Acetylcholine receptor subunit alpha-type acr-16 precursor - Caenorhabditis elegans Length = 498 Score = 63.7 bits (148), Expect = 6e-09 Identities = 46/169 (27%), Positives = 76/169 (44%), Gaps = 7/169 (4%) Frame = +2 Query: 59 TCAIASAAECENATSLSLMIDSLLATYDRDSPPDSKIVVNLTLHLRHA-----NIRESES 223 +CAI +A + L D L+ Y+ P + +T+HL+ A ++ E Sbjct: 9 SCAILAAPTLGSLQERRLYED-LMRNYNNLERPVANHSEPVTVHLKVALQQIIDVDEKNQ 67 Query: 224 TVRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGD-YALRA 397 V + A L W D L W+ E+G T + + ++W+PDV+L N+ T Y Sbjct: 68 VVYVNAWLDYTWNDYNLVWDKAEYGNITDVRFPAGKIWKPDVLLYNSVDTNFDSTYQTNM 127 Query: 398 RVSNNGSVSWIKRLDISTPISMQLDSWPNDMQTCTFKFGSRMHNSDEMD 544 V + G V W+ + + +P D Q C FKFGS ++ ++D Sbjct: 128 IVYSTGLVHWVPPGIFKISCKIDIQWFPFDEQKCFFKFGSWTYDGYKLD 176 >UniRef50_Q7T2S3 Cluster: Nicotinic acetylcholine receptor alpha 4 subunit; n=2; Tetraodontidae|Rep: Nicotinic acetylcholine receptor alpha 4 subunit - Fugu rubripes (Japanese pufferfish) (Takifugu rubripes) Length = 622 Score = 63.3 bits (147), Expect = 8e-09 Identities = 40/156 (25%), Positives = 76/156 (48%), Gaps = 10/156 (6%) Frame = +2 Query: 113 MIDSLLATYDRDSPPDSKIVVNLTLHL-----RHANIRESESTVRIQADLQMNWIDKRLS 277 ++ L A Y++ S P + +H + ++ E + ++ W D +L Sbjct: 14 LLQDLFAHYNKLSRPVENTTDTVLVHFGLSIAQLIDVDEKNQMMTTNVWVKQEWNDYKLR 73 Query: 278 WNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNGSVSWIKRLD 442 WN E+ T + + SE +WRPD+VL N A GD+A+ +A++ +G + W+ Sbjct: 74 WNPEEYENVTSIRIPSEIIWRPDIVLYNNAD---GDFAVTHLTKAQLFYDGRIKWMPPAI 130 Query: 443 ISTPISMQLDSWPNDMQTCTFKFGSRMHNSDEMDFV 550 + S+ + +P D Q+C KFGS ++ ++D + Sbjct: 131 YKSSCSIDVTFFPFDQQSCKMKFGSWTYDRAKIDLI 166 >UniRef50_Q8WSF7 Cluster: GABA A receptor alpha subunit; n=1; Aplysia californica|Rep: GABA A receptor alpha subunit - Aplysia californica (California sea hare) Length = 448 Score = 63.3 bits (147), Expect = 8e-09 Identities = 41/154 (26%), Positives = 71/154 (46%), Gaps = 7/154 (4%) Frame = +2 Query: 101 SLSLMIDSLLATYDRDSPPD---SKIVVNLTLHLRHAN-IRESESTVRIQADLQMNWIDK 268 ++S ++DSLL YD+ P + VN + LR I E + + W+D Sbjct: 33 NISQVLDSLLEGYDKRLRPGFGGEALTVNADISLRSMGPISELNMIYTLDCYFRQRWMDH 92 Query: 269 RLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAAT---TAGDYALRARVSNNGSVSWIKRL 439 RL+ N + + ER+W PD V N + + R++ NG+V + +RL Sbjct: 93 RLAMNVSLENLTLGIKILERIWHPDTVFYNGQKSYLHAITSHNRFLRIAANGTVLFSQRL 152 Query: 440 DISTPISMQLDSWPNDMQTCTFKFGSRMHNSDEM 541 I M +++P D+Q C GS +++D++ Sbjct: 153 TIQATCRMHPENFPMDIQHCPLLIGSFAYSTDDV 186 >UniRef50_Q0GQR6 Cluster: GABA-gated ion channel; n=2; Apis mellifera|Rep: GABA-gated ion channel - Apis mellifera (Honeybee) Length = 463 Score = 63.3 bits (147), Expect = 8e-09 Identities = 40/149 (26%), Positives = 70/149 (46%), Gaps = 7/149 (4%) Frame = +2 Query: 92 NATSLSLMIDSLLATYDRDSPPD---SKIVVNLTLHLRHAN-IRESESTVRIQADLQMNW 259 N +++S ++D+LL YD PD V + + +R I E + T + + +W Sbjct: 2 NHSNISELLDNLLRGYDNSVRPDFGGPPATVEVDIMVRSMGPISEVDMTYSMDCYFRQSW 61 Query: 260 IDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAAT---TAGDYALRARVSNNGSVSWI 430 +D+RL++ G+ + + R+W+PD N + T R+ +G V + Sbjct: 62 VDRRLAFQGGKETLALSISMLARIWKPDTYFYNGKHSYLHTITSPNKFVRLYQDGRVLYS 121 Query: 431 KRLDISTPISMQLDSWPNDMQTCTFKFGS 517 RL I M L+++P D Q C +FGS Sbjct: 122 SRLTIKAGCPMNLENFPMDTQRCPLQFGS 150 >UniRef50_P17787 Cluster: Neuronal acetylcholine receptor subunit beta-2 precursor; n=69; Euteleostomi|Rep: Neuronal acetylcholine receptor subunit beta-2 precursor - Homo sapiens (Human) Length = 502 Score = 63.3 bits (147), Expect = 8e-09 Identities = 39/139 (28%), Positives = 64/139 (46%), Gaps = 3/139 (2%) Frame = +2 Query: 167 IVVNLTLHLRHA-NIRESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 340 + V L + L ++ E E + L W D RL+W E+ + S+ +W P Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115 Query: 341 DVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDSWPNDMQTCTFKFGS 517 DVVL N A + A VS +GS+ W+ + +++ +P D Q CT KF S Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRS 175 Query: 518 RMHNSDEMDFVIDKRIYSM 574 ++ E+D V+ + S+ Sbjct: 176 WTYDRTEIDLVLKSEVASL 194 >UniRef50_P43681 Cluster: Neuronal acetylcholine receptor subunit alpha-4 precursor; n=35; Euteleostomi|Rep: Neuronal acetylcholine receptor subunit alpha-4 precursor - Homo sapiens (Human) Length = 627 Score = 63.3 bits (147), Expect = 8e-09 Identities = 44/156 (28%), Positives = 78/156 (50%), Gaps = 10/156 (6%) Frame = +2 Query: 113 MIDSLLATYDRDSPPDSKI--VVNLTLHLRHA---NIRESESTVRIQADLQMNWIDKRLS 277 ++ L + Y++ S P + I VV + L A ++ E + ++ W D +L Sbjct: 40 LLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLR 99 Query: 278 WNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNGSVSWIKRLD 442 W+ ++ T + + SE +WRPD+VL N A GD+A+ +A + ++G V W Sbjct: 100 WDPADYENVTSIRIPSELIWRPDIVLYNNAD---GDFAVTHLTKAHLFHDGRVQWTPPAI 156 Query: 443 ISTPISMQLDSWPNDMQTCTFKFGSRMHNSDEMDFV 550 + S+ + +P D Q CT KFGS ++ ++D V Sbjct: 157 YKSSCSIDVTFFPFDQQNCTMKFGSWTYDKAKIDLV 192 >UniRef50_P04755 Cluster: Acetylcholine receptor subunit beta-like 1 precursor; n=20; Protostomia|Rep: Acetylcholine receptor subunit beta-like 1 precursor - Drosophila melanogaster (Fruit fly) Length = 521 Score = 63.3 bits (147), Expect = 8e-09 Identities = 32/122 (26%), Positives = 60/122 (49%), Gaps = 5/122 (4%) Frame = +2 Query: 203 NIRESESTVRIQADLQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLLNAAATTAG 379 N+ E ++ L++ W D +L W+ ++G + +++W+PD+VL N A G Sbjct: 66 NVNEKNQVMKSNVWLRLVWYDYQLQWDEADYGGIGVLRLPPDKVWKPDIVLFNNAD---G 122 Query: 380 DYALRAR----VSNNGSVSWIKRLDISTPISMQLDSWPNDMQTCTFKFGSRMHNSDEMDF 547 +Y +R + + G V W+ + ++ + +P D QTC KFGS N D++ Sbjct: 123 NYEVRYKSNVLIYPTGEVLWVPPAIYQSSCTIDVTYFPFDQQTCIMKFGSWTFNGDQVSL 182 Query: 548 VI 553 + Sbjct: 183 AL 184 >UniRef50_UPI0000E49402 Cluster: PREDICTED: similar to alpha 10 subunit of nicotinic acetylcholine receptor; n=1; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to alpha 10 subunit of nicotinic acetylcholine receptor - Strongylocentrotus purpuratus Length = 473 Score = 62.9 bits (146), Expect = 1e-08 Identities = 33/98 (33%), Positives = 52/98 (53%), Gaps = 2/98 (2%) Frame = +2 Query: 257 WIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLL-NAAATTAGDYALRARVSNNGSVSWI 430 W D L WN ++G +T L V E +WRPD+VL NA ++ G A +S++G V W Sbjct: 80 WTDSNLKWNPADYGDTTVLIVPIETIWRPDIVLFTNADSSFNGMMMTSASISHDGIVRWN 139 Query: 431 KRLDISTPISMQLDSWPNDMQTCTFKFGSRMHNSDEMD 544 + + + +P D Q C+ KFGS ++ ++D Sbjct: 140 APAIYQSTCKIDITYFPFDEQHCSLKFGSWAYHGFQID 177 >UniRef50_Q4RIA9 Cluster: Chromosome 8 SCAF15044, whole genome shotgun sequence; n=3; Clupeocephala|Rep: Chromosome 8 SCAF15044, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 549 Score = 62.9 bits (146), Expect = 1e-08 Identities = 40/139 (28%), Positives = 65/139 (46%), Gaps = 3/139 (2%) Frame = +2 Query: 167 IVVNLTLHLRHA-NIRESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 340 + V L + L ++ E E + L W D RL+W E+ G + S+ +W P Sbjct: 30 VTVQLMVSLAQLISVHEREQVMTTNVWLTQEWQDYRLTWIPEEFDGMLKVRLPSKHIWLP 89 Query: 341 DVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDSWPNDMQTCTFKFGS 517 DVVL N A + A VS +GS+ W+ + +++ +P D Q CT +F S Sbjct: 90 DVVLYNNADGVYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTLRFRS 149 Query: 518 RMHNSDEMDFVIDKRIYSM 574 ++ E+D V+ + SM Sbjct: 150 WTYDRTEIDLVLRADVASM 168 >UniRef50_Q2XWL0 Cluster: Nicotinic acetylcholine receptor subunit type C; n=1; Lymnaea stagnalis|Rep: Nicotinic acetylcholine receptor subunit type C - Lymnaea stagnalis (Great pond snail) Length = 506 Score = 62.9 bits (146), Expect = 1e-08 Identities = 40/136 (29%), Positives = 66/136 (48%), Gaps = 6/136 (4%) Frame = +2 Query: 155 PDSKIVVNLTLHLRHA-NIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSER 328 P K+ V L L L ++ E + I L+ W D RL W E+G L + S++ Sbjct: 54 PMKKLTVKLGLRLSQVLSVDERNQILTISVWLRQEWYDFRLKWEPSEYGGVNVLNIPSDQ 113 Query: 329 LWRPDVVLLNAAATTAGDYAL----RARVSNNGSVSWIKRLDISTPISMQLDSWPNDMQT 496 LW+PD+VL N A GD+ + +A V++ G + W + + ++ +P D+Q Sbjct: 114 LWKPDLVLYNNA---DGDFQITLKTKAIVNHTGRIVWEPPAIYKSYCPIDVEYFPFDIQE 170 Query: 497 CTFKFGSRMHNSDEMD 544 C K S ++ E+D Sbjct: 171 CFLKISSWTYHGHELD 186 >UniRef50_A7UFK6 Cluster: Nicotinic acetylcholine receptor alpha subunit; n=2; Ascaris suum|Rep: Nicotinic acetylcholine receptor alpha subunit - Ascaris suum (Pig roundworm) (Ascaris lumbricoides) Length = 513 Score = 62.9 bits (146), Expect = 1e-08 Identities = 40/148 (27%), Positives = 68/148 (45%), Gaps = 7/148 (4%) Frame = +2 Query: 113 MIDSLLATYDRDS----PPDSKIVVNLTLHLRHA-NIRESESTVRIQADLQMNWIDKRLS 277 + D L+ Y++ P + + L L L ++ E + + L+ WIDK+LS Sbjct: 28 LYDDLMVNYNKHRRPAMSPHEPVTIKLKLRLSQIIDVHEIDQIMTYSVWLKQVWIDKKLS 87 Query: 278 WNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAG-DYALRARVSNNGSVSWIKRLDIST 451 W+ + G S V E +W PD+VL N A + + +A + +G V+W + Sbjct: 88 WDPKNYGGVSVLYVPYEMIWVPDIVLYNNADSNYNITISTKATLHYSGEVTWEPPAIFKS 147 Query: 452 PISMQLDSWPNDMQTCTFKFGSRMHNSD 535 + + +P D Q C KFGS ++ D Sbjct: 148 MCQIDVRWFPFDEQKCHLKFGSWTYSED 175 >UniRef50_A7SW63 Cluster: Predicted protein; n=3; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 324 Score = 62.9 bits (146), Expect = 1e-08 Identities = 38/154 (24%), Positives = 76/154 (49%), Gaps = 10/154 (6%) Frame = +2 Query: 113 MIDSLLATYDRDSPP----DSKIVVNLTLHLRHA-NIRESESTVRIQADLQMNWIDKRLS 277 ++ LL Y +D+ P + + + L + LR ++ E + + I ++ W D L Sbjct: 4 LLKYLLQNYSKDARPVLNVNDPVQLKLGIMLRQVIDLNERDQILTINVWIRQYWKDHLLK 63 Query: 278 WNAGEWG-CSTWLVSSERLWRPDVVLLNAAATTAGDYALRAR----VSNNGSVSWIKRLD 442 WN ++G + ++ +R+W+PDV+L N G + V+++GS +W+ Sbjct: 64 WNPDDFGGIKSINIAPDRVWKPDVLLYNRTDLRFGSLNNKIDTNVIVNHDGSTTWLAPAI 123 Query: 443 ISTPISMQLDSWPNDMQTCTFKFGSRMHNSDEMD 544 I + + + +P D+Q+C FGS H+ ++D Sbjct: 124 IKSECKIDVRFFPFDVQSCELTFGSWTHDGLKID 157 >UniRef50_P54245 Cluster: Uncharacterized acetylcholine receptor-like protein F18G5.4 precursor; n=2; Caenorhabditis|Rep: Uncharacterized acetylcholine receptor-like protein F18G5.4 precursor - Caenorhabditis elegans Length = 615 Score = 62.9 bits (146), Expect = 1e-08 Identities = 32/114 (28%), Positives = 58/114 (50%), Gaps = 3/114 (2%) Frame = +2 Query: 212 ESESTVRIQADLQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLLNAAATT--AGD 382 E + ++ L +NW+D RLSWN W + R+W+PD++L+N A A Sbjct: 154 ERNQALTTRSWLNINWMDPRLSWNESLWSEIKAIYIPHARIWKPDIILVNNAIREYYASL 213 Query: 383 YALRARVSNNGSVSWIKRLDISTPISMQLDSWPNDMQTCTFKFGSRMHNSDEMD 544 + V+++G+V+W+ + +++ +P D Q C KF S H+ E++ Sbjct: 214 VSTDVMVTSDGNVTWLFSALFRSSCPIRVRYYPFDDQQCDLKFASWSHDITEIN 267 >UniRef50_Q4S866 Cluster: Chromosome 5 SCAF14709, whole genome shotgun sequence; n=1; Tetraodon nigroviridis|Rep: Chromosome 5 SCAF14709, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 215 Score = 62.5 bits (145), Expect = 1e-08 Identities = 28/99 (28%), Positives = 55/99 (55%), Gaps = 1/99 (1%) Frame = +2 Query: 245 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 421 + + W D +L W+ E+ G + V S+R+WRPDVVL + + +A V ++G++ Sbjct: 45 VDVEWTDMKLRWSPEEYVGITIIRVPSDRIWRPDVVLYDNSDGRFEGTVTKAVVKHDGTI 104 Query: 422 SWIKRLDISTPISMQLDSWPNDMQTCTFKFGSRMHNSDE 538 +W + + ++ + +P D+Q C+ KFGS ++ + Sbjct: 105 TWTAPANYKSACTIDVTFFPFDLQNCSMKFGSWTYDGSQ 143 >UniRef50_P07510 Cluster: Acetylcholine receptor subunit gamma precursor; n=31; Gnathostomata|Rep: Acetylcholine receptor subunit gamma precursor - Homo sapiens (Human) Length = 517 Score = 62.5 bits (145), Expect = 1e-08 Identities = 43/157 (27%), Positives = 76/157 (48%), Gaps = 8/157 (5%) Frame = +2 Query: 113 MIDSLLATYDRDSPPDSKI--VVNLTLHLRHANI---RESESTVRIQADLQMNWIDKRLS 277 ++ L+ YD + P + VVN++L L N+ E E + ++M W D RL Sbjct: 29 LLADLMQNYDPNLRPAERDSDVVNVSLKLTLTNLISLNEREEALTTNVWIEMQWCDYRLR 88 Query: 278 WNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARV--SNNGSVSWIKRLDIS 448 W+ ++ G V S +WRPD+VL N + AL V S +G + W+ Sbjct: 89 WDPRDYEGLWVLRVPSTMVWRPDIVLENNVDGVF-EVALYCNVLVSPDGCIYWLPPAIFR 147 Query: 449 TPISMQLDSWPNDMQTCTFKFGSRMHNSDEMDFVIDK 559 + S+ + +P D Q C+ F S+ ++++E+D + + Sbjct: 148 SACSISVTYFPFDWQNCSLIFQSQTYSTNEIDLQLSQ 184 >UniRef50_A7RLP3 Cluster: Predicted protein; n=3; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 417 Score = 62.1 bits (144), Expect = 2e-08 Identities = 44/156 (28%), Positives = 72/156 (46%), Gaps = 11/156 (7%) Frame = +2 Query: 125 LLATYDR---DSPPDSKIVVNLTLH-LRHANIRESESTVRIQADLQMNWIDKRLSWNAGE 292 LL YD+ S PD ++ +N +L ++ ++++ E V ++ MNWI+ L W+ + Sbjct: 20 LLDGYDKVVLPSEPD-RLALNFSLKFVQIMDVKDKEQLVSVECWYSMNWINSFLKWDKKK 78 Query: 293 W-GCSTWLVSSERLWRPDVVLLN----AAATTAG--DYALRARVSNNGSVSWIKRLDIST 451 + S +W PD+ L N T+ G + V + G W + + Sbjct: 79 YQNESRVFFDPSEIWVPDIALYNNGDDKVQTSGGRTKFLTNIVVEDTGKCVWSGPVTFTF 138 Query: 452 PISMQLDSWPNDMQTCTFKFGSRMHNSDEMDFVIDK 559 SM L WP D Q CT KFGS + + +F+I K Sbjct: 139 TCSMALSRWPFDDQNCTMKFGSLSYGKN--NFIISK 172 >UniRef50_A7RHV9 Cluster: Predicted protein; n=3; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 336 Score = 62.1 bits (144), Expect = 2e-08 Identities = 38/138 (27%), Positives = 70/138 (50%), Gaps = 8/138 (5%) Frame = +2 Query: 176 NLTLHLRHANIRESESTVRIQAD---LQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPD 343 N+TL + +I + + +I + ++ +WI + LSW+ E+G + +VSS+ LW+PD Sbjct: 38 NVTLDITFNSIIDVDEKHQILSSSVWIRQSWIAETLSWDPAEYGGVNQIVVSSQLLWQPD 97 Query: 344 VVLLNAAA----TTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDSWPNDMQTCTFKF 511 VL N + R RV ++G V W T + + +P D Q C F Sbjct: 98 TVLYNNIFEEFDSRLDTTVTRVRVYSSGFVYWAMPYVFKTMCKIDVTDFPFDSQRCPITF 157 Query: 512 GSRMHNSDEMDFVIDKRI 565 G+ ++ +E++ + +KR+ Sbjct: 158 GAWQYDQNEVNLINNKRL 175 >UniRef50_A2TM48 Cluster: Nicotinic acetylcholine receptor alpha 1 subunit; n=3; Aphidinae|Rep: Nicotinic acetylcholine receptor alpha 1 subunit - Sitobion avenae (English grain aphid) Length = 496 Score = 62.1 bits (144), Expect = 2e-08 Identities = 49/162 (30%), Positives = 74/162 (45%), Gaps = 12/162 (7%) Frame = +2 Query: 68 IASAAECENATSLSLMIDSLLATYDRDSPPDSK----IVVNLTLHLRHA---NIRESEST 226 + SA C T + D LL+ Y+R P S ++V L L L N+++ T Sbjct: 12 LLSAVGCLCNTDAKRLYDDLLSNYNRLIRPVSNNTDTVLVKLGLRLSQLIELNLKDQILT 71 Query: 227 VRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYAL---- 391 + L+ W D + W E+G L V SE +W PD+VL N A G+Y + Sbjct: 72 TNVW--LEHEWADHKFIWEPLEYGGVKELYVPSEHIWLPDIVLYNNAD---GEYVVTTMT 126 Query: 392 RARVSNNGSVSWIKRLDISTPISMQLDSWPNDMQTCTFKFGS 517 +A + ++G V W + + + +P D QTC KFGS Sbjct: 127 KAVLHHSGKVMWTPPAIFKSSCEIDVRYFPFDQQTCFMKFGS 168 >UniRef50_Q66T21 Cluster: Nicotinic acetylcholine receptor subunit alpha 9; n=4; Culicidae|Rep: Nicotinic acetylcholine receptor subunit alpha 9 - Anopheles gambiae (African malaria mosquito) Length = 406 Score = 61.7 bits (143), Expect = 3e-08 Identities = 40/137 (29%), Positives = 60/137 (43%), Gaps = 6/137 (4%) Frame = +2 Query: 125 LLATYD---RDSPPDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWNAGEW 295 LL YD R S + V + + H I E +ST+ + ++ +W D +L+WN + Sbjct: 46 LLKGYDPSIRPSQHYNVTTVETGITITHVEINEIKSTLSVYGWMKFSWNDPKLTWNPASY 105 Query: 296 G-CSTWLVSSERLWRPDVVLL-NAAATTAGDYA-LRARVSNNGSVSWIKRLDISTPISMQ 466 G + +WRPDVVL NA + Y V + G V W+ + + Sbjct: 106 GNLNVVRWDPTIVWRPDVVLYNNAGGSDQHHYGDTNVLVYSEGKVLWVPPTEYHAFCELN 165 Query: 467 LDSWPNDMQTCTFKFGS 517 + WP D Q C K GS Sbjct: 166 MRLWPFDYQKCIVKIGS 182 >UniRef50_Q23022 Cluster: Acetylcholine receptor subunit alpha-type unc-38 precursor; n=9; Chromadorea|Rep: Acetylcholine receptor subunit alpha-type unc-38 precursor - Caenorhabditis elegans Length = 511 Score = 61.7 bits (143), Expect = 3e-08 Identities = 38/142 (26%), Positives = 66/142 (46%), Gaps = 7/142 (4%) Frame = +2 Query: 113 MIDSLLATYDR----DSPPDSKIVVNLTLHLRHA-NIRESESTVRIQADLQMNWIDKRLS 277 + D L+ Y+R + P+ + + L L L ++ E + + L+ WID++LS Sbjct: 30 LYDDLMVNYNRHRRPSTSPNKPLTIKLKLRLSQIIDVHEIDQIMTCSVWLKQTWIDRKLS 89 Query: 278 WNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAG-DYALRARVSNNGSVSWIKRLDIST 451 W+ + G + V E +W PD+VL N A + + +A + G V+W + Sbjct: 90 WDPVNYGGVNVLYVPYEMIWVPDIVLYNNADSNYNITISTKATLHYTGEVTWEPPAIFKS 149 Query: 452 PISMQLDSWPNDMQTCTFKFGS 517 + + +P D Q C KFGS Sbjct: 150 MCQIDVRWFPFDEQQCHLKFGS 171 >UniRef50_Q4SXG5 Cluster: Chromosome undetermined SCAF12416, whole genome shotgun sequence; n=3; Tetraodontidae|Rep: Chromosome undetermined SCAF12416, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 643 Score = 61.3 bits (142), Expect = 3e-08 Identities = 44/166 (26%), Positives = 83/166 (50%), Gaps = 6/166 (3%) Frame = +2 Query: 65 AIASAAECENATSLSLMIDSLLATYDRDSPPDSKIVVNLTLHLRH---ANIRESESTVRI 235 ++ A E E+A +L + L SP + ++VV + + L N++ E + + Sbjct: 16 SLGGAFEVESALLKNLFSNYTLKVRPAVSP-EQRVVVRVGMILSSFVGLNMKNEEMSTIV 74 Query: 236 QADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVS-- 406 +L+ W D RLSW+ ++ G + S ++W PD+VL+N + AL+ V Sbjct: 75 VMNLE--WTDYRLSWSPKDYDGIEVLRIPSGKIWLPDIVLINNNDGVF-EVALQVHVQVY 131 Query: 407 NNGSVSWIKRLDISTPISMQLDSWPNDMQTCTFKFGSRMHNSDEMD 544 +NG V+W + ++++ +P D Q C+ +F S ++S E+D Sbjct: 132 SNGRVTWTPPALYCSSCGVKVEYFPFDWQNCSMQFRSYTYDSTEID 177 >UniRef50_Q8JFN7 Cluster: Neuronal acetylcholine receptor subunit alpha-9-I precursor; n=8; Clupeocephala|Rep: Neuronal acetylcholine receptor subunit alpha-9-I precursor - Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri) Length = 572 Score = 61.3 bits (142), Expect = 3e-08 Identities = 37/154 (24%), Positives = 70/154 (45%), Gaps = 7/154 (4%) Frame = +2 Query: 113 MIDSLLATYDRDSPP--DSKIVVNLTLHLRHANIRESESTVRIQAD---LQMNWIDKRLS 277 +++ L+ Y P D+ +N+TL + + I++ + ++ ++ W D L Sbjct: 28 LLNDLMENYSSALRPVEDTDKTLNVTLQITLSQIKDMDERNQVLTTYLWIRQTWFDAYLK 87 Query: 278 WNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTA-GDYALRARVSNNGSVSWIKRLDIST 451 W+ E+ G + S +WRPD+VL N A A G + NG ++W + Sbjct: 88 WDKEEYDGLEVIRIPSNLVWRPDIVLYNKADEEASGPADTNVVLRYNGEITWDMPAITKS 147 Query: 452 PISMQLDSWPNDMQTCTFKFGSRMHNSDEMDFVI 553 + + +P D Q C FGS +N +++D + Sbjct: 148 SCVVDVSYFPFDWQWCNLTFGSWTYNGNQVDIAM 181 >UniRef50_Q65XS8 Cluster: Acetylcholine receptor protein 25; n=2; Caenorhabditis elegans|Rep: Acetylcholine receptor protein 25 - Caenorhabditis elegans Length = 544 Score = 60.9 bits (141), Expect = 4e-08 Identities = 39/133 (29%), Positives = 65/133 (48%), Gaps = 3/133 (2%) Frame = +2 Query: 167 IVVNLTLHLRH-ANIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRP 340 ++V + L L+ ++ E V + A L+ +W+D L W ++G T L +LW P Sbjct: 51 VMVKMGLVLQQIVDVDEKNQVVDVNAWLKFSWVDYSLKWKPEDYGGVTDLRFRKGQLWTP 110 Query: 341 DVVLLNAAATTAGD-YALRARVSNNGSVSWIKRLDISTPISMQLDSWPNDMQTCTFKFGS 517 DV++ N+A YA V NG V+W+ +Q+ +P D+Q C KFGS Sbjct: 111 DVLMYNSADPQFDSRYASNLLVYPNGLVNWMPPGLYRLSCKIQVVWFPFDVQECFLKFGS 170 Query: 518 RMHNSDEMDFVID 556 + +++ ID Sbjct: 171 WTFDGTKLNLEID 183 >UniRef50_Q2XWK5 Cluster: Nicotinic acetylcholine receptor subunit type H; n=1; Lymnaea stagnalis|Rep: Nicotinic acetylcholine receptor subunit type H - Lymnaea stagnalis (Great pond snail) Length = 450 Score = 60.9 bits (141), Expect = 4e-08 Identities = 42/152 (27%), Positives = 68/152 (44%), Gaps = 6/152 (3%) Frame = +2 Query: 107 SLMIDSLLATYDRD----SPPDSKIVVNLTLHLRHAN-IRESESTVRIQADLQMNWIDKR 271 S ++ LL YDR P + V+ L L+ + E + + + W D R Sbjct: 25 SRLMRDLLTDYDRRVRPVQRPSDTVHVSFGLGLKALLFVDEKREYMETVSYMLTAWHDGR 84 Query: 272 LSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVSWIKRLDIS 448 L WN ++ G T + + LW PD+V + A + +G VSWI L + Sbjct: 85 LMWNMSQYAGIDTIKIPAVDLWTPDIVPYTSIDEDIHLMETMAVIYASGHVSWIPTLHLR 144 Query: 449 TPISMQLDSWPNDMQTCTFKFGSRMHNSDEMD 544 +P S+ L +P D Q C+ KF S ++ D ++ Sbjct: 145 SPCSVNLKYFPFDEQKCSIKFASYGYHGDHLN 176 >UniRef50_Q29ND1 Cluster: GA17977-PA; n=3; Schizophora|Rep: GA17977-PA - Drosophila pseudoobscura (Fruit fly) Length = 531 Score = 60.9 bits (141), Expect = 4e-08 Identities = 41/155 (26%), Positives = 74/155 (47%), Gaps = 7/155 (4%) Frame = +2 Query: 113 MIDSLLATYDRDSPP----DSKIVVNLTLHLRHA-NIRESESTVRIQADLQMNWIDKRLS 277 +++ LL+TY+ P + V L L+ ++ E + L + W D L Sbjct: 14 LLNHLLSTYNTLERPVANESEPLEVKFGLTLQQIIDVDEKNQLLITNLWLSLEWNDYNLR 73 Query: 278 WNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTA-GDYALRARVSNNGSVSWIKRLDIST 451 WN E+G L ++ +LW+PDV++ N+A G Y V +NGS ++ + Sbjct: 74 WNETEYGGVKDLRITPNKLWKPDVLMYNSADEGFDGTYHTNIVVKHNGSCLYVPPGIFKS 133 Query: 452 PISMQLDSWPNDMQTCTFKFGSRMHNSDEMDFVID 556 + + +P D Q C KFGS ++ +++D V++ Sbjct: 134 TCKIDITWFPFDDQHCEMKFGSWTYDGNQLDLVLN 168 >UniRef50_O16926 Cluster: Acetylcholine receptor protein 15; n=2; Caenorhabditis|Rep: Acetylcholine receptor protein 15 - Caenorhabditis elegans Length = 479 Score = 60.9 bits (141), Expect = 4e-08 Identities = 41/150 (27%), Positives = 73/150 (48%), Gaps = 7/150 (4%) Frame = +2 Query: 113 MIDSLLATYDRDSPP--DSK--IVVNLTLHLRHA-NIRESESTVRIQADLQMNWIDKRLS 277 +I+ L++ Y R+ P DS +VV+L + L+ N+ E E + + A L+ W D+ L Sbjct: 25 LINDLMSGYVREERPTLDSSKPVVVSLGVFLQQIINLSEKEEQLEVNAWLKFQWRDENLR 84 Query: 278 WNAGEWGCSTWLVSS-ERLWRPDVVLLNAAATTA-GDYALRARVSNNGSVSWIKRLDIST 451 W + T L + LW PD++L N+ + Y + + G+++W+ Sbjct: 85 WEPTAYENVTDLRHPPDALWTPDILLYNSVDSEFDSSYKVNLVNYHTGNINWMPPGIFKV 144 Query: 452 PISMQLDSWPNDMQTCTFKFGSRMHNSDEM 541 + + +P D Q C FKFGS + D++ Sbjct: 145 SCKLDIYWFPFDEQVCYFKFGSWTYTRDKI 174 >UniRef50_O46132 Cluster: Nicotinic acetylcholine receptor, alpha1 subunit; n=1; Locusta migratoria|Rep: Nicotinic acetylcholine receptor, alpha1 subunit - Locusta migratoria (Migratory locust) Length = 559 Score = 60.1 bits (139), Expect = 8e-08 Identities = 31/102 (30%), Positives = 51/102 (50%), Gaps = 2/102 (1%) Frame = +2 Query: 245 LQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 418 ++ W D +L WN ++G T V SE +W PD+VL N + A +A + + G Sbjct: 37 VEQEWNDYKLKWNPDDYGGVDTLHVPSEHIWLPDIVLTNNSEGNFEVTLATKATIYHQGL 96 Query: 419 VSWIKRLDISTPISMQLDSWPNDMQTCTFKFGSRMHNSDEMD 544 V W + + ++ +P D QTC KFGS ++ ++D Sbjct: 97 VEWKPPAIYKSSCEIDVEYFPFDEQTCVLKFGSWTYDGFKVD 138 >UniRef50_A7RLM4 Cluster: Predicted protein; n=2; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 300 Score = 60.1 bits (139), Expect = 8e-08 Identities = 39/156 (25%), Positives = 74/156 (47%), Gaps = 8/156 (5%) Frame = +2 Query: 137 YDRDSPPDSK--IVVNLTLHLRHANIRESESTVRI---QADLQMNWIDKRLSWNAGEW-G 298 YD P + + +N+T + I E ++ + +++ +W+D L+WN ++ G Sbjct: 3 YDPQVRPSDRADMPINITFGISLNEIYELTDRTQLLITKVEIRESWVDTSLAWNKSDFEG 62 Query: 299 CSTWLVSSERLWRPDVVLLNAAATTAGDYALR--ARVSNNGSVSWIKRLDISTPISMQLD 472 + ++ E +WRPD+VL N A GD R A V+++G VS + T + Sbjct: 63 LAKIVLRPESIWRPDIVLYNNAGEDFGDGQTRTNAVVTSDGLVSMTIPSILKTSCKIDAT 122 Query: 473 SWPNDMQTCTFKFGSRMHNSDEMDFVIDKRIYSMFE 580 +P D Q+C FGS ++ + + ++ + E Sbjct: 123 RYPFDKQSCPMIFGSWTYDGNLLSIKMESHSADLSE 158 >UniRef50_A0EIZ9 Cluster: Nicotinic acetylcholine receptor beta2 subunit; n=1; Apis mellifera|Rep: Nicotinic acetylcholine receptor beta2 subunit - Apis mellifera (Honeybee) Length = 427 Score = 60.1 bits (139), Expect = 8e-08 Identities = 40/160 (25%), Positives = 71/160 (44%), Gaps = 8/160 (5%) Frame = +2 Query: 86 CENATSLSLMIDS---LLATYDRDSPPDSKIV--VNLTLHLRHANIRESESTVRIQADLQ 250 C++ TS S + L YDRD P+ K ++ L ++H N+ E TV L+ Sbjct: 28 CKDITSTSALYRLKLYLFCDYDRDIIPEQKNATKIDFGLSIQHYNVDEYSHTVDFHVMLK 87 Query: 251 MNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVL--LNAAATTAGDYALRARVSNNGSV 421 + W L+W + E+ ++ V S +W PD+V+ + + ++ V N+G++ Sbjct: 88 LMWEQSHLTWKSSEFDSINSIRVKSYEIWVPDIVMHSVTSVGIDLEMPSVECIVFNSGTI 147 Query: 422 SWIKRLDISTPISMQLDSWPNDMQTCTFKFGSRMHNSDEM 541 + + WP D+ CT S H S+E+ Sbjct: 148 LCVPFTTYTPVCEYDHTWWPYDILNCTIHIASWSHGSNEI 187 >UniRef50_UPI0000D55E50 Cluster: PREDICTED: similar to AcetylCholine Receptor family member (acr-21); n=3; Endopterygota|Rep: PREDICTED: similar to AcetylCholine Receptor family member (acr-21) - Tribolium castaneum Length = 649 Score = 59.7 bits (138), Expect = 1e-07 Identities = 38/162 (23%), Positives = 73/162 (45%), Gaps = 8/162 (4%) Frame = +2 Query: 83 ECENATSLSLMIDSLLATYDRDSPPDSKIVVNLT----LHLRHA-NIRESESTVRIQADL 247 EC+ + + ++ L+ YD P + LT + L H ++ E + + Sbjct: 13 ECQGDENEARLMRHLMTNYDAAVRPVENSSLPLTVIFGISLHHIIDVDEKNQILTTNCWI 72 Query: 248 QMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARV--SNNGS 418 WID L WNA ++ G + R+WRPD++L N A + V S++G Sbjct: 73 TQAWIDHHLRWNASDFAGIKVIRIPYTRVWRPDLILYNNADPQFQSSVINTNVIVSSSGE 132 Query: 419 VSWIKRLDISTPISMQLDSWPNDMQTCTFKFGSRMHNSDEMD 544 V W+ + + ++ +P D+Q+C K+ S ++ +++ Sbjct: 133 VLWLSHGIYRSSCDINVEYFPFDLQSCHMKWASWTYDGYQVE 174 >UniRef50_Q23355 Cluster: Putative uncharacterized protein acr-8; n=2; Caenorhabditis|Rep: Putative uncharacterized protein acr-8 - Caenorhabditis elegans Length = 537 Score = 59.7 bits (138), Expect = 1e-07 Identities = 37/120 (30%), Positives = 56/120 (46%), Gaps = 2/120 (1%) Frame = +2 Query: 191 LRHANIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAA 367 +R ++ E + L+M W D RL W+ G WG L V +++W PD++L N A Sbjct: 59 IRIIDVDEVNQVLTTNLWLEMQWFDYRLMWDPGRWGKIRKLHVPVDQIWIPDILLYNNAD 118 Query: 368 TTAGDYALR-ARVSNNGSVSWIKRLDISTPISMQLDSWPNDMQTCTFKFGSRMHNSDEMD 544 + A V NG V W + S+ ++ +P D QTC KFG +N +D Sbjct: 119 GEPHITIMSDAIVYYNGLVVWKPPSIYKSFCSIDIEYFPYDTQTCWMKFGGWTYNGFLLD 178 >UniRef50_A5H038 Cluster: Nicotinic acetylcholine receptor subunit 6 isoform VIII; n=1; Musca domestica|Rep: Nicotinic acetylcholine receptor subunit 6 isoform VIII - Musca domestica (House fly) Length = 396 Score = 59.7 bits (138), Expect = 1e-07 Identities = 40/154 (25%), Positives = 73/154 (47%), Gaps = 7/154 (4%) Frame = +2 Query: 113 MIDSLLATYDRDSPP----DSKIVVNLTLHLRHA-NIRESESTVRIQADLQMNWIDKRLS 277 +++ LL+TY+ P + V L L+ ++ E + L + W D L Sbjct: 29 LLNHLLSTYNTLERPVANESDPLEVKFGLTLQQIIDVDEKNQLLITNLWLSLEWNDYNLR 88 Query: 278 WNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTA-GDYALRARVSNNGSVSWIKRLDIST 451 WN E+G L ++ +LW+PDV++ N+A G Y V +NG+ ++ + Sbjct: 89 WNDSEYGGVKDLRITPNKLWKPDVLMYNSADEGFDGTYHTNIVVKHNGNCLYVPPGIFKS 148 Query: 452 PISMQLDSWPNDMQTCTFKFGSRMHNSDEMDFVI 553 + + +P D Q C KFGS ++ +++D V+ Sbjct: 149 TCKIDITWFPFDDQHCEMKFGSWTYDGNQLDLVL 182 >UniRef50_Q7Z6B2 Cluster: 5-hydroxytryptamine serotonin receptor 3E; n=30; Theria|Rep: 5-hydroxytryptamine serotonin receptor 3E - Homo sapiens (Human) Length = 471 Score = 59.7 bits (138), Expect = 1e-07 Identities = 29/114 (25%), Positives = 58/114 (50%), Gaps = 1/114 (0%) Frame = +2 Query: 245 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 421 L+M W + +SWN E G + ++++ LW PD+ ++ L A VSN G + Sbjct: 106 LEMVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEGRI 165 Query: 422 SWIKRLDISTPISMQLDSWPNDMQTCTFKFGSRMHNSDEMDFVIDKRIYSMFES 583 + K + + + ++ + +P D Q CT F S ++ D M ++K ++ + ++ Sbjct: 166 RYKKPMKVDSICNLDIFYFPFDQQNCTLTFSSFLYTVDSMLLDMEKEVWEITDA 219 >UniRef50_UPI0000E49844 Cluster: PREDICTED: similar to nicotinic acetylcholine receptor alpha2 subunit; n=1; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to nicotinic acetylcholine receptor alpha2 subunit - Strongylocentrotus purpuratus Length = 570 Score = 59.3 bits (137), Expect = 1e-07 Identities = 45/171 (26%), Positives = 81/171 (47%), Gaps = 10/171 (5%) Frame = +2 Query: 68 IASAAECENATSLSLMIDSLLATYDRDSPP---DSKIV-VNLTLHLRHA-NIRESESTVR 232 +A A C ++ + + L Y+R P +S+++ VN L + ++ E + Sbjct: 67 LAFAQGCTSSEAEERLFTKLFYKYNRLIRPVENNSEVLDVNFRLTMSQLIDVDEKNQIMT 126 Query: 233 IQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYAL----RA 397 L+ W+D +L WN E+ S V S+ +W PD+VL N A G+Y + +A Sbjct: 127 TNVWLKQLWMDYKLQWNPAEYDNISILRVPSKMIWTPDLVLYNNAD---GNYEVTLMAKA 183 Query: 398 RVSNNGSVSWIKRLDISTPISMQLDSWPNDMQTCTFKFGSRMHNSDEMDFV 550 V ++G+V W+ + + + +P D Q C KFGS ++ +D + Sbjct: 184 LVYSDGTVYWLPPAIYKSSCKINVRYFPFDEQFCPMKFGSWTYDGSLIDLI 234 >UniRef50_A7S622 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 299 Score = 59.3 bits (137), Expect = 1e-07 Identities = 35/135 (25%), Positives = 64/135 (47%), Gaps = 6/135 (4%) Frame = +2 Query: 158 DSKIVVNLTLHLRH-ANIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERL 331 D+ +V L+ +++++E ++I M W + L+W+ ++G + V+ E + Sbjct: 23 DAPAIVTFRAKLKQIVDLKDNEQLLKIILYNYMQWENPILTWDPRDYGGVQEINVAPEEV 82 Query: 332 WRPDVVLLNAAATTAGD----YALRARVSNNGSVSWIKRLDISTPISMQLDSWPNDMQTC 499 W PD+V+ N+A G Y + NG+ W+ T + + +P D Q C Sbjct: 83 WVPDIVIYNSAEDVLGGLTHKYKTDVVIQANGTNIWLAPAMFLTTCQLDVRYFPFDEQKC 142 Query: 500 TFKFGSRMHNSDEMD 544 KFGS H+S +D Sbjct: 143 LLKFGSWTHDSSRLD 157 >UniRef50_A7RUG1 Cluster: Predicted protein; n=2; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 497 Score = 59.3 bits (137), Expect = 1e-07 Identities = 38/160 (23%), Positives = 76/160 (47%), Gaps = 11/160 (6%) Frame = +2 Query: 113 MIDSLLATYDRDSPP-----DSKIVVNLTLHL-RHANIRESESTVRIQADLQMNWIDKRL 274 ++ LL Y++D+ P ++ +V L L + N+ + + ++ W + L Sbjct: 15 LLGDLLKGYNKDAHPVPILNKTQYMVTFGLELVQLVNVDDKNQIITTNVWVRQRWTNLLL 74 Query: 275 SWNAGEWGCSTWL-VSSERLWRPDVVLLNAAAT--TAG--DYALRARVSNNGSVSWIKRL 439 W+ ++G T + + + ++W PD+VL N+A + + G Y R ++++G +W Sbjct: 75 KWDPDKYGGITRVRIDASKIWIPDIVLYNSADSEFSGGLEKYKTRVILNHDGVNAWYSPA 134 Query: 440 DISTPISMQLDSWPNDMQTCTFKFGSRMHNSDEMDFVIDK 559 + + + +P D QTC KFGS ++D DK Sbjct: 135 SFRSTCQIDVTFFPFDQQTCFMKFGSWTFEVVDLDIFADK 174 >UniRef50_A6QL44 Cluster: Nicotinic acetylcholine receptor non-alpha subunit precursor ShAR2beta; n=1; Schistosoma haematobium|Rep: Nicotinic acetylcholine receptor non-alpha subunit precursor ShAR2beta - Schistosoma haematobium (Blood fluke) Length = 545 Score = 59.3 bits (137), Expect = 1e-07 Identities = 33/130 (25%), Positives = 64/130 (49%), Gaps = 3/130 (2%) Frame = +2 Query: 164 KIVVNLTLHL-RHANIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWR 337 K+VV L + + + E++ +R W D L WNA ++G L + ++W Sbjct: 60 KMVVQYGLQMIQLLGLDENKQVLRTNCWAVYRWSDSLLKWNASQYGGIKELRIFPHQIWT 119 Query: 338 PDVVLLNAAATTAGDYAL-RARVSNNGSVSWIKRLDISTPISMQLDSWPNDMQTCTFKFG 514 PD+ L N A ++ R V ++G++ WI++ + +++ +P D Q C +FG Sbjct: 120 PDIKLYNFADERLQEFREGRLVVDSSGNILWIQQALFRSTCQVEITYFPFDSQVCMLEFG 179 Query: 515 SRMHNSDEMD 544 S ++ ++D Sbjct: 180 SMAYDKTQLD 189 >UniRef50_Q9U298 Cluster: Neuronal acetylcholine receptor subunit eat-2 precursor; n=1; Caenorhabditis elegans|Rep: Neuronal acetylcholine receptor subunit eat-2 precursor - Caenorhabditis elegans Length = 474 Score = 59.3 bits (137), Expect = 1e-07 Identities = 44/155 (28%), Positives = 72/155 (46%), Gaps = 7/155 (4%) Frame = +2 Query: 113 MIDSLLATYDRDSPP--DSKIVVNLTLHL---RHANIRESESTVRIQADLQMNWIDKRLS 277 ++ L YD P D + VN+ L L + ++ E + + Q W D +L Sbjct: 28 LLKDLREGYDPVERPVADHRKPVNVKLRLILQQLVDVDERNQVITLVVWNQYTWNDYKLR 87 Query: 278 WNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTA-GDYALRARVSNNGSVSWIKRLDIST 451 W+ E+G T L + LW+PD++L N+A + + VS+NG V + +S Sbjct: 88 WSPEEYGNITTLQIPHGTLWKPDILLFNSANEHFDASFPVHMVVSSNGDVLFAPPGIVSF 147 Query: 452 PISMQLDSWPNDMQTCTFKFGSRMHNSDEMDFVID 556 S+ + +P D Q C KFGS + ++D ID Sbjct: 148 SCSLSMTWFPYDQQVCYLKFGSWTYGK-KLDLQID 181 >UniRef50_UPI00015B5C6B Cluster: PREDICTED: similar to nicotinic acetylcholine receptor alpha9 subunit; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to nicotinic acetylcholine receptor alpha9 subunit - Nasonia vitripennis Length = 304 Score = 58.8 bits (136), Expect = 2e-07 Identities = 38/152 (25%), Positives = 67/152 (44%), Gaps = 9/152 (5%) Frame = +2 Query: 125 LLATYDRDSPPD-----SKIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWNAG 289 L YD D P + V L R + ++ + + + MNW D L+WN Sbjct: 48 LFCDYDEDVRPQIGAKGNATNVGLMFMPRFISFDDASNVFEMHSWSIMNWTDPHLTWNPE 107 Query: 290 EW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYAL---RARVSNNGSVSWIKRLDISTPI 457 ++ G T V S+ LW PD+ + N + G + +S++G V+ + + ST Sbjct: 108 DFEGLDTIQVPSDSLWTPDIAVHNTHDASKGKPGIAKTNCGLSHDGHVTCVPAVKYSTNC 167 Query: 458 SMQLDSWPNDMQTCTFKFGSRMHNSDEMDFVI 553 +P D+Q CT S +++DE+ ++ Sbjct: 168 LPDFTDYPYDLQVCTIDLASWAYSTDEIQLLM 199 >UniRef50_UPI0000E48B7E Cluster: PREDICTED: similar to neuronal nicotinic acetylcholine receptor alpha3 subunit; n=1; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to neuronal nicotinic acetylcholine receptor alpha3 subunit - Strongylocentrotus purpuratus Length = 525 Score = 58.8 bits (136), Expect = 2e-07 Identities = 30/115 (26%), Positives = 57/115 (49%), Gaps = 2/115 (1%) Frame = +2 Query: 206 IRESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAG- 379 I E + ++ W D L WN ++ G + + +E +WRPD++L N A Sbjct: 72 IDEKNQVMTTSVWVKHEWQDHHLMWNPEDYEGITELHIPAENIWRPDILLYNNANGNFDV 131 Query: 380 DYALRARVSNNGSVSWIKRLDISTPISMQLDSWPNDMQTCTFKFGSRMHNSDEMD 544 + + A V G+V+W+ + ++ ++ +P D Q+C KFG H++ ++D Sbjct: 132 QFLVNAIVKYTGTVTWLPPAIYKSSCTIDIEYFPFDEQSCKMKFGPWTHDTLKID 186 >UniRef50_Q9GQ00 Cluster: Serotonin-gated chloride channel; n=4; Caenorhabditis|Rep: Serotonin-gated chloride channel - Caenorhabditis elegans Length = 489 Score = 58.8 bits (136), Expect = 2e-07 Identities = 44/162 (27%), Positives = 78/162 (48%), Gaps = 10/162 (6%) Frame = +2 Query: 89 ENATSLSLMIDSLLATYDRDSPP-DSKIVVNLTLHLRH-ANIRESESTVRIQADLQMNWI 262 E A S +++++++ Y + P + + VN+ +H++ ++ E S I W Sbjct: 29 EGAWSEGKIMNTIMSNYTKMLPDAEDSVQVNIEIHVQDMGSLNEISSDFEIDILFTQLWH 88 Query: 263 DKRLSWNAGEWGCSTWLVSSERL----WRPDVVLLNAAATT---AGDYALRARVSNNGSV 421 D LS+ A C + RL W P+ ++N+ TT + + + NG+V Sbjct: 89 DSALSF-AHLPACKRNITMETRLLPKIWSPNTCMINSKRTTVHASPSENVMVILYENGTV 147 Query: 422 SWIK-RLDISTPISMQLDSWPNDMQTCTFKFGSRMHNSDEMD 544 WI RL + +P ++ L +P D QTC F S HNS+E++ Sbjct: 148 -WINHRLSVKSPCNLDLRQFPFDTQTCILIFESYSHNSEEVE 188 >UniRef50_A7SNK1 Cluster: Predicted protein; n=2; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 526 Score = 58.8 bits (136), Expect = 2e-07 Identities = 35/108 (32%), Positives = 55/108 (50%), Gaps = 6/108 (5%) Frame = +2 Query: 245 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAA-----ATTAGDYALRARVS 406 ++MNW + L WNA E+G L +S +W PD+VL N A A T + + ++ Sbjct: 136 VRMNWNNHLLRWNASEYGGIDKLNISPTLMWLPDIVLHNNAEENVPAGTLYQFKTKVQLF 195 Query: 407 NNGSVSWIKRLDISTPISMQLDSWPNDMQTCTFKFGSRMHNSDEMDFV 550 N+G W I + ++ + +P D Q C KFGS +N E++ V Sbjct: 196 NDGLCVWYAPTIIQSGCNIDITYFPFDDQLCELKFGSWTYNGLEVNIV 243 >UniRef50_Q7KT97 Cluster: CG32975-PB, isoform B; n=69; Eumetazoa|Rep: CG32975-PB, isoform B - Drosophila melanogaster (Fruit fly) Length = 808 Score = 58.4 bits (135), Expect = 2e-07 Identities = 31/102 (30%), Positives = 51/102 (50%), Gaps = 2/102 (1%) Frame = +2 Query: 245 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTA-GDYALRARVSNNGS 418 L++ W D L WN ++G L + R+W+PDV++ N+A G Y V NNGS Sbjct: 365 LKLEWNDMNLRWNTSDYGGVKDLRIPPHRIWKPDVLMYNSADEGFDGTYQTNVVVRNNGS 424 Query: 419 VSWIKRLDISTPISMQLDSWPNDMQTCTFKFGSRMHNSDEMD 544 ++ + + + +P D Q C KFGS ++ ++D Sbjct: 425 CLYVPPGIFKSTCKIDITWFPFDDQRCEMKFGSWTYDGFQLD 466 >UniRef50_A7T134 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 301 Score = 58.4 bits (135), Expect = 2e-07 Identities = 44/149 (29%), Positives = 66/149 (44%), Gaps = 14/149 (9%) Frame = +2 Query: 113 MIDSLLATYDRDSPP--DSKIVVNLTLHLRHANI-----RESESTVRIQADLQMNWIDKR 271 ++D L YD+ P D VV L L L+ I +E E R+ + W D + Sbjct: 4 LLDQLFQGYDKRVRPVTDPSDVVELKLGLKIQKIVKIDSKEQEMITRVW--VTQVWRDPK 61 Query: 272 LSWNAGEWG-CSTWLVSSERLWRPDVVLLNAA---ATTAGD---YALRARVSNNGSVSWI 430 L W+ + G T V +W PD+ L N A + AG + + V+N G V W Sbjct: 62 LRWDVEKGGGIETIFVDPSEIWTPDISLYNNADDSVSVAGSEKKFQTKIVVANTGKVVWQ 121 Query: 431 KRLDISTPISMQLDSWPNDMQTCTFKFGS 517 + S+++ WP D+Q C+ FGS Sbjct: 122 SPATFRSECSIKIRYWPFDVQKCSMTFGS 150 >UniRef50_A7RK99 Cluster: Predicted protein; n=2; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 446 Score = 58.4 bits (135), Expect = 2e-07 Identities = 44/168 (26%), Positives = 74/168 (44%), Gaps = 12/168 (7%) Frame = +2 Query: 89 ENATSLSLMIDSLLATYDRDSPPDS---KIVVNLTLHLRHANIRESES---TVRIQADLQ 250 +NA +L D LL YDR P S + ++ LT L+ + + ++ + + A + Sbjct: 24 QNAVRKALRAD-LLKDYDRIVGPVSHSPRSLLELTFVLKITKLNKVDTKNQVISVNAWVF 82 Query: 251 MNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAA---ATTAGDYAL---RARVSNN 412 W D L W+ ++ S + +W PDV L+N AG L V + Sbjct: 83 QQWKDPSLQWDKAKYNLHKTRFSPKEIWVPDVSLINNGDKLVHVAGGAELFNADTVVRQS 142 Query: 413 GSVSWIKRLDISTPISMQLDSWPNDMQTCTFKFGSRMHNSDEMDFVID 556 G V WI + ++ ++++ WP D Q CT F S + E+ +D Sbjct: 143 GKVDWIAQASFTSTCNLRVRFWPMDDQFCTLTFSSWTYTESEIALKMD 190 >UniRef50_UPI0000E47C58 Cluster: PREDICTED: similar to nicotinic acetylcholine receptor beta 5 subunit; n=1; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to nicotinic acetylcholine receptor beta 5 subunit - Strongylocentrotus purpuratus Length = 477 Score = 58.0 bits (134), Expect = 3e-07 Identities = 31/102 (30%), Positives = 50/102 (49%), Gaps = 3/102 (2%) Frame = +2 Query: 245 LQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLLNAAATTAGDYALRA--RVSNNG 415 L + W D L W + + ++ + +W PD+ L N A + DYA + V + G Sbjct: 58 LDVRWHDDYLVWEPTRYNNVKNFKITRDDVWMPDLWLYNNAGSRYEDYAAHSICSVYHTG 117 Query: 416 SVSWIKRLDISTPISMQLDSWPNDMQTCTFKFGSRMHNSDEM 541 V W I T +M + ++P D+QTCT FG H ++E+ Sbjct: 118 KVVWQSPTIIKTHCTMDVTNFPFDVQTCTVTFGPWQHGANEI 159 >UniRef50_P91197 Cluster: Acetylcholine receptor protein 11; n=2; Caenorhabditis|Rep: Acetylcholine receptor protein 11 - Caenorhabditis elegans Length = 461 Score = 57.6 bits (133), Expect = 4e-07 Identities = 42/166 (25%), Positives = 72/166 (43%), Gaps = 9/166 (5%) Frame = +2 Query: 86 CENATSLSLMIDSLLATYDRDSPP----DSKIVVNLTLHLRHA-NIRESESTVRIQADLQ 250 C+ + + + + LL Y+ P + V + L L+ ++ E V + A L Sbjct: 20 CDGSVAETKLFTDLLKGYNPLERPVQNSSQPLEVKIKLFLQQILDVDEKNQIVSVNAWLS 79 Query: 251 MNWIDKRLSWNAGEWGCSTWLV---SSERLWRPDVVLLNAAATT-AGDYALRARVSNNGS 418 W D +L W ++G + SS+ +W+PDV+L N+AA + + G+ Sbjct: 80 YTWFDHKLQWEPKKYGGIQDIRFPGSSDHIWKPDVLLYNSAAEDFDSTFKSNLLTYHTGT 139 Query: 419 VSWIKRLDISTPISMQLDSWPNDMQTCTFKFGSRMHNSDEMDFVID 556 V WI + + + +P D Q C KFGS + +D ID Sbjct: 140 VVWIPPGVLKFVCQLDVTWFPFDDQVCEMKFGSWTFHGYAIDLQID 185 >UniRef50_O62083 Cluster: Putative uncharacterized protein acr-19; n=2; Caenorhabditis|Rep: Putative uncharacterized protein acr-19 - Caenorhabditis elegans Length = 554 Score = 57.6 bits (133), Expect = 4e-07 Identities = 33/118 (27%), Positives = 57/118 (48%), Gaps = 2/118 (1%) Frame = +2 Query: 203 NIRESESTVRIQADLQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLLNAAATTAG 379 +I E + L+M+W D L+W+ E+G + +W+PDV+L N+ Sbjct: 63 DIDEKHQIMNSNVWLRMSWTDHYLTWDPSEFGNIKEVRLPINNIWKPDVLLYNSVDQQFD 122 Query: 380 D-YALRARVSNNGSVSWIKRLDISTPISMQLDSWPNDMQTCTFKFGSRMHNSDEMDFV 550 + + A V G+V+WI I + ++ + +P D Q CT KFGS ++ D + Sbjct: 123 STWPVNAVVLYTGNVTWIPPAIIRSSCAIDIAYFPFDTQHCTMKFGSWTYSGFFTDLI 180 >UniRef50_O61519 Cluster: Ligand-gated ion channel protein 6; n=4; Caenorhabditis elegans|Rep: Ligand-gated ion channel protein 6 - Caenorhabditis elegans Length = 462 Score = 57.6 bits (133), Expect = 4e-07 Identities = 38/156 (24%), Positives = 73/156 (46%), Gaps = 6/156 (3%) Frame = +2 Query: 68 IASAAECENATSLSLMIDSLLATYDRD-SPPDSKIVVNLTLH-LRHANIRESESTVRIQA 241 + + A E + + +L+ TYD D P D +V +T + ++ +++ T++ Sbjct: 17 LTAVAFLETSNTETLLQQLFNQTYDVDMKPSDDLTMVTITPNTFILLSMDQTQETIQYSE 76 Query: 242 DLQMNWIDKRLSWNAGEWGCST-WL-VSSERLWRPDVVLLNAA-ATTAGDYALR-ARVSN 409 + + W D L WN W+ +S+ R W PDV+ N D ++ A + Sbjct: 77 EFLLRWYDPILHWNQSAVSYENDWIKISASRAWIPDVIFTNGIDMDPLLDKDMQMADLRY 136 Query: 410 NGSVSWIKRLDISTPISMQLDSWPNDMQTCTFKFGS 517 NG + + +S+P +++D++P D+Q C GS Sbjct: 137 NGEIRTSRPAVVSSPCPLEIDNFPYDVQKCNISMGS 172 >UniRef50_P25162 Cluster: Acetylcholine receptor subunit beta-like 2 precursor; n=7; Diptera|Rep: Acetylcholine receptor subunit beta-like 2 precursor - Drosophila melanogaster (Fruit fly) Length = 519 Score = 57.6 bits (133), Expect = 4e-07 Identities = 44/156 (28%), Positives = 69/156 (44%), Gaps = 12/156 (7%) Frame = +2 Query: 113 MIDSLLATYDRDSPPDSKIVVNLTL-------HLRHANIRESESTVRIQADLQMNWIDKR 271 + D LL+ Y+R P LT+ L N++ T + ++ W D + Sbjct: 33 LYDDLLSNYNRLIRPVVNNTETLTVWLGLKLSQLIEVNLKNQVMTTNLW--VKQRWFDYK 90 Query: 272 LSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNGSVSWIKR 436 L W+ E+G L V SE +W PD+VL N G+Y + +A + G V W Sbjct: 91 LRWDPEEYGGVEQLYVPSEHIWVPDIVLYN---NWDGNYEVTLMTKATLKYTGEVFWEPP 147 Query: 437 LDISTPISMQLDSWPNDMQTCTFKFGSRMHNSDEMD 544 + M ++ +P D Q C KFGS +N ++D Sbjct: 148 AIYKSSCEMNVEYFPYDEQICFMKFGSWTYNGAQVD 183 >UniRef50_A7SI11 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 404 Score = 57.2 bits (132), Expect = 5e-07 Identities = 41/154 (26%), Positives = 70/154 (45%), Gaps = 11/154 (7%) Frame = +2 Query: 113 MIDSLLATYDRDSPP----DSKIVVNLTLHLRHANIRESESTVRIQAD-LQMNWIDKRLS 277 ++ LLA Y P + V+N T+ L+ + + + ++ W D +L Sbjct: 5 LVTDLLAGYHDSQRPALDNNEPTVINFTIRLQQIYELNGQLQKMVSSVWIEQAWWDHKLQ 64 Query: 278 WNAGEWGCSTWLVSSER--LWRPDVVLLNAAATTAGDYALR----ARVSNNGSVSWIKRL 439 W+ ++G +V ER +W PDVVLLN A ++ + V +NG V W+ + Sbjct: 65 WDQSKYGGIKEVVLPERGVIWVPDVVLLNNAEKSSMGKPVNEGNPVLVESNGVVRWLAPV 124 Query: 440 DISTPISMQLDSWPNDMQTCTFKFGSRMHNSDEM 541 + + M + S+P D Q C KF S + E+ Sbjct: 125 VLKSRCKMDVRSYPFDEQYCGLKFASWTGSQSEL 158 >UniRef50_Q07001 Cluster: Acetylcholine receptor subunit delta precursor; n=38; Gnathostomata|Rep: Acetylcholine receptor subunit delta precursor - Homo sapiens (Human) Length = 517 Score = 57.2 bits (132), Expect = 5e-07 Identities = 35/131 (26%), Positives = 62/131 (47%), Gaps = 3/131 (2%) Frame = +2 Query: 158 DSKIVVNLTLHLRHA-NIRESESTVRIQADLQMNWIDKRLSWNAGEWG-CSTWLVSSERL 331 + + V L L L + +++E E T+ ++ W D RL WNA E+G S + + + Sbjct: 49 EESVDVALALTLSNLISLKEVEETLTTNVWIEHGWTDNRLKWNAEEFGNISVLRLPPDMV 108 Query: 332 WRPDVVL-LNAAATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDSWPNDMQTCTFK 508 W P++VL N + Y+ V + G V W+ + + + +P D Q C+ K Sbjct: 109 WLPEIVLENNNDGSFQISYSCNVLVYHYGFVYWLPPAIFRSSCPISVTYFPFDWQNCSLK 168 Query: 509 FGSRMHNSDEM 541 F S + + E+ Sbjct: 169 FSSLKYTAKEI 179 >UniRef50_UPI0000E464AB Cluster: PREDICTED: similar to nicotinic acetylcholine receptor; n=1; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to nicotinic acetylcholine receptor - Strongylocentrotus purpuratus Length = 528 Score = 56.8 bits (131), Expect = 7e-07 Identities = 32/105 (30%), Positives = 51/105 (48%), Gaps = 5/105 (4%) Frame = +2 Query: 245 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYALR----ARVSN 409 ++ W D RL W+ ++G T + + LW+PD+VL N G YA+ +V Sbjct: 68 VRQRWEDYRLVWDPADYGNITMVHIPIFLLWKPDIVLYN---NVGGSYAITMLTMTQVYP 124 Query: 410 NGSVSWIKRLDISTPISMQLDSWPNDMQTCTFKFGSRMHNSDEMD 544 NG+V W + + + +P D Q C KFGS H+ ++D Sbjct: 125 NGTVDWFPPAVYRSSCPINIHDFPFDEQRCPLKFGSWTHDYSKID 169 >UniRef50_UPI0000ECB6ED Cluster: Acetylcholine receptor subunit alpha precursor.; n=1; Gallus gallus|Rep: Acetylcholine receptor subunit alpha precursor. - Gallus gallus Length = 352 Score = 56.8 bits (131), Expect = 7e-07 Identities = 38/145 (26%), Positives = 66/145 (45%), Gaps = 10/145 (6%) Frame = +2 Query: 113 MIDSLLATYDRDSPPDSK----IVVNLTLHL-RHANIRESESTVRIQADLQMNWIDKRLS 277 ++D L Y + P +VV + L L + N+ E V L+ W D L Sbjct: 26 LVDDLFRDYSKVVRPVENHRDAVVVTVGLQLIQLINVDEVNQIVTTNVRLKQQWTDINLK 85 Query: 278 WNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNGSVSWIKRLD 442 WN ++G + + S+ +WRPD+VL N A GD+A+ + + + G ++W Sbjct: 86 WNPDDYGGVKQIRIPSDDIWRPDLVLYNNA---DGDFAIVKYTKVLLEHTGKITWTPPAI 142 Query: 443 ISTPISMQLDSWPNDMQTCTFKFGS 517 + + + +P D Q C+ K G+ Sbjct: 143 FKSYCEIIVTYFPFDQQNCSMKLGT 167 >UniRef50_Q4RZC6 Cluster: Chromosome 1 SCAF14944, whole genome shotgun sequence; n=1; Tetraodon nigroviridis|Rep: Chromosome 1 SCAF14944, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 547 Score = 56.8 bits (131), Expect = 7e-07 Identities = 28/105 (26%), Positives = 50/105 (47%), Gaps = 2/105 (1%) Frame = +2 Query: 245 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATT-AGDYALRARVSNNGS 418 ++ W D L WN ++ G + S +WRPD+VL N A +G ++ NG Sbjct: 139 IRQRWNDAYLKWNKEDYDGLEVIHIPSSLVWRPDLVLYNKADDDFSGPMDTNVKLRYNGE 198 Query: 419 VSWIKRLDISTPISMQLDSWPNDMQTCTFKFGSRMHNSDEMDFVI 553 ++W + + + +P D Q C FGS +N +++D ++ Sbjct: 199 ITWDAPAITKSSCVVDVSYFPFDSQECNLTFGSWTYNGNQVDIIM 243 >UniRef50_UPI0000E4930A Cluster: PREDICTED: similar to nicotinic acetylcholine receptor subunit Dalpha7; n=1; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to nicotinic acetylcholine receptor subunit Dalpha7 - Strongylocentrotus purpuratus Length = 1094 Score = 56.4 bits (130), Expect = 9e-07 Identities = 29/102 (28%), Positives = 50/102 (49%), Gaps = 2/102 (1%) Frame = +2 Query: 245 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGD-YALRARVSNNGS 418 ++ W D L+WN E+G + V + +WRPD+++ N+AA + + V++ G Sbjct: 757 MRQRWTDPTLAWNKSEYGGLDKIRVLPDMIWRPDILVYNSAAPKFDPTFHTKVTVTSEGL 816 Query: 419 VSWIKRLDISTPISMQLDSWPNDMQTCTFKFGSRMHNSDEMD 544 WI T + + +P D+Q C KFGS + +D Sbjct: 817 CEWIPPGIFKTSCPIDVTYFPFDIQECEIKFGSWTYGGFTVD 858 >UniRef50_Q9GP98 Cluster: Acetylcholine receptor protein 22; n=3; Caenorhabditis|Rep: Acetylcholine receptor protein 22 - Caenorhabditis elegans Length = 434 Score = 56.4 bits (130), Expect = 9e-07 Identities = 38/136 (27%), Positives = 67/136 (49%), Gaps = 7/136 (5%) Frame = +2 Query: 170 VVNLTLHLRHAN---IRESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWR 337 V+N+T+ + N + E ++I +W D L+W+ EW G ++ ++W Sbjct: 60 VLNVTVQPQIYNLVEVNEQNEQIKILLWFPQSWKDDYLTWDPKEWNGIERIIIPKSQIWI 119 Query: 338 PDVVLLNAAATTAGDYALRARVSNNG--SVSWIKRLDISTPISMQLDSWPNDMQTCTFKF 511 PD + N T ARV +G V + K +D++ P+S+ S+P D+Q C +F Sbjct: 120 PDGYIFNTVEETEPLENHNARVRYDGRVEVDFNKLVDLTCPMSVL--SFPFDVQLCALQF 177 Query: 512 GSRMHNSDEMDF-VID 556 GS + + + F V+D Sbjct: 178 GSWSYQAHAISFNVLD 193 >UniRef50_Q2XWL2 Cluster: Nicotinic acetylcholine receptor subunit type A; n=1; Lymnaea stagnalis|Rep: Nicotinic acetylcholine receptor subunit type A - Lymnaea stagnalis (Great pond snail) Length = 485 Score = 56.4 bits (130), Expect = 9e-07 Identities = 34/133 (25%), Positives = 61/133 (45%), Gaps = 3/133 (2%) Frame = +2 Query: 167 IVVNLTLHLRHA-NIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRP 340 I VN + L+ ++ E + L+M W L W+ E+G T + V + +W P Sbjct: 53 INVNFGIILQQIIDVDEKNQIIHTNIWLRMTWNAANLMWDPKEYGNLTSIRVPKQMVWVP 112 Query: 341 DVVLLNAAATTAGD-YALRARVSNNGSVSWIKRLDISTPISMQLDSWPNDMQTCTFKFGS 517 D++L N+A+ D Y ++ NG+ W+ + ++ + +P D Q C K+GS Sbjct: 113 DILLYNSASDGFDDTYPTNVVINYNGNCLWVPPGMFKSTCAIDITWFPFDDQRCNLKYGS 172 Query: 518 RMHNSDEMDFVID 556 H ++ D Sbjct: 173 WTHEGHLLNLTAD 185 >UniRef50_Q2XWK9 Cluster: Nicotinic acetylcholine receptor subunit type D; n=1; Lymnaea stagnalis|Rep: Nicotinic acetylcholine receptor subunit type D - Lymnaea stagnalis (Great pond snail) Length = 554 Score = 56.4 bits (130), Expect = 9e-07 Identities = 35/135 (25%), Positives = 63/135 (46%), Gaps = 2/135 (1%) Frame = +2 Query: 164 KIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRP 340 K+++ +TL + ++ E + L W D++L WN ++ L + LW+P Sbjct: 106 KVLIGITL-TQIFDLDEKNQVLTTNVWLDQEWTDQKLHWNPTDYNDLKRLRIPCRHLWKP 164 Query: 341 DVVLLNAAAT-TAGDYALRARVSNNGSVSWIKRLDISTPISMQLDSWPNDMQTCTFKFGS 517 D+VL N+ T G A V + G V W + + + + +P D Q C+ K GS Sbjct: 165 DIVLYNSVEDYTDGYMQSLAMVHHTGVVFWPPIVRFQSTCQVDITYFPFDDQVCSMKLGS 224 Query: 518 RMHNSDEMDFVIDKR 562 ++ ++D +D R Sbjct: 225 WAYDGFQVD--VDNR 237 >UniRef50_O18228 Cluster: Putative uncharacterized protein lgc-7; n=4; Caenorhabditis|Rep: Putative uncharacterized protein lgc-7 - Caenorhabditis elegans Length = 439 Score = 56.4 bits (130), Expect = 9e-07 Identities = 40/169 (23%), Positives = 75/169 (44%), Gaps = 8/169 (4%) Frame = +2 Query: 83 ECENATSLSLMIDSLLATYDRDSPPDSK----IVVNLTLHLRHA-NIRESESTVRIQADL 247 E + T + D L+ YD P + +++N++++ + +E T+ ++ Sbjct: 21 EVDGITVAEQLKDVLMEGYDSSIRPVNNERDILIINISMNTMSVLTLDPAEETINFSSEF 80 Query: 248 QMNWIDKRLSWNAGEWGCSTWLVSSER-LWRPDVVLLNAAATT-AGDYALR-ARVSNNGS 418 + W D+ L WN ++ TWL E LW PD + + T D + R V ++G+ Sbjct: 81 ILQWKDEFLFWNKSDYNI-TWLKLKESFLWTPDTTVSTSIDTNYLIDASERYVSVKHDGT 139 Query: 419 VSWIKRLDISTPISMQLDSWPNDMQTCTFKFGSRMHNSDEMDFVIDKRI 565 V + M +D +P D QTC K G + + E+ ++ + I Sbjct: 140 VRQSIYAVFTNLCDMNVDKFPYDQQTCMIKMGPWSYTTQEVTCIVGRDI 188 >UniRef50_A7S9T6 Cluster: Predicted protein; n=2; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 321 Score = 56.4 bits (130), Expect = 9e-07 Identities = 34/155 (21%), Positives = 76/155 (49%), Gaps = 10/155 (6%) Frame = +2 Query: 110 LMIDSLLATYDRDSPPDSKI--VVNLTLHLRHA---NIRESESTVRIQADLQMNWIDKRL 274 L+ L A Y P ++ VV ++ + ++ N+ E + +++ W D L Sbjct: 6 LLYKHLFANYSNVVRPVKRVEEVVPVSFDIGYSQMVNLVEKNQILISNLWVRLKWYDPWL 65 Query: 275 SWNAGEWG-CSTWLVSSERLWRPDVVLLNAA-ATTAGD---YALRARVSNNGSVSWIKRL 439 +WN ++G + V +W PD+VL N + ++G+ + + + ++G+V W+ + Sbjct: 66 TWNESDFGGMKSIKVDPSCVWVPDIVLYNNVDSDSSGEMYKFTTKVNIHSDGTVQWLSPI 125 Query: 440 DISTPISMQLDSWPNDMQTCTFKFGSRMHNSDEMD 544 + + + + ++P D Q C +FGS ++ E++ Sbjct: 126 QVKSECKIDITNFPLDEQFCKLEFGSWAYDGFELN 160 >UniRef50_Q9UGM1 Cluster: Neuronal acetylcholine receptor subunit alpha-9 precursor; n=30; Euteleostomi|Rep: Neuronal acetylcholine receptor subunit alpha-9 precursor - Homo sapiens (Human) Length = 479 Score = 56.4 bits (130), Expect = 9e-07 Identities = 38/163 (23%), Positives = 75/163 (46%), Gaps = 7/163 (4%) Frame = +2 Query: 77 AAECENATSLSLMIDSLLATYDRDSPP--DSKIVVNLTLHLRHANIRESESTVRIQAD-- 244 AAE + + + L Y P D+ V+N+TL + + I++ + +I Sbjct: 22 AAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQITLSQIKDMDERNQILTAYL 81 Query: 245 -LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGD-YALRARVSNNG 415 ++ W D L+W+ ++ G + + S+ +WRPD+VL N A + + + +G Sbjct: 82 WIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKADDESSEPVNTNVVLRYDG 141 Query: 416 SVSWIKRLDISTPISMQLDSWPNDMQTCTFKFGSRMHNSDEMD 544 ++W + + + +P D Q C FGS +N +++D Sbjct: 142 LITWDAPAITKSSCVVDVTYFPFDNQQCNLTFGSWTYNGNQVD 184 >UniRef50_UPI0000D56893 Cluster: PREDICTED: similar to CG6698-PA; n=1; Tribolium castaneum|Rep: PREDICTED: similar to CG6698-PA - Tribolium castaneum Length = 419 Score = 56.0 bits (129), Expect = 1e-06 Identities = 33/118 (27%), Positives = 54/118 (45%), Gaps = 4/118 (3%) Frame = +2 Query: 173 VNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVV 349 V L L + E +S ++ + + W D++L WN E+G +T + +W P++ Sbjct: 224 VGLKLGTNIVTLNEYKSVLQYSGTISLTWHDEKLHWNTSEYGDINTLHIFRREIWIPELF 283 Query: 350 LLNAAATTAGDYA--LRARVSNNGSVSWIKRLDISTPISM-QLDSWPNDMQTCTFKFG 514 L NA A G+ V++ G V WI ++I++ S L WP D C G Sbjct: 284 LFNAIAEN-GELLEDTMLTVNSTGHVKWITTININSWCSPDDLGRWPRDEHQCDIVLG 340 >UniRef50_UPI0000E47621 Cluster: PREDICTED: similar to nicotinic acetylcholine receptor subunit type G, partial; n=1; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to nicotinic acetylcholine receptor subunit type G, partial - Strongylocentrotus purpuratus Length = 283 Score = 55.6 bits (128), Expect = 2e-06 Identities = 40/159 (25%), Positives = 69/159 (43%), Gaps = 5/159 (3%) Frame = +2 Query: 89 ENATSLSLMIDSLLATYDRDSP-PDSKIVVNLTLHLRHA-NIRESESTVRIQADLQMNWI 262 E A +S ++D +T R + I V + L + + ++ E+ + + W Sbjct: 11 EEALLVSRLLDHGYSTIVRPVMYQEDTITVKIDLAIVNLLDMDEANQIMTANTFMTQEWN 70 Query: 263 DKRLSWNAGE-WGCSTWLVSSERLWRPDVVLLNAA--ATTAGDYALRARVSNNGSVSWIK 433 D L W E W + V +WRPD++L N A G A + +G+V+W Sbjct: 71 DAFLQWEPSESWNITDVQVPINNIWRPDIILHNNANDELNGGIRWTHAWIRYDGTVTWKT 130 Query: 434 RLDISTPISMQLDSWPNDMQTCTFKFGSRMHNSDEMDFV 550 + + M +P D Q C+ K GS +N DE++ + Sbjct: 131 NYILMSACPMNPLYFPFDTQNCSLKLGSWTYNEDEINVI 169 >UniRef50_Q6Q069 Cluster: Neuronal nicotinic acetylcholine Apisa7-2 subunit; n=3; Apis mellifera|Rep: Neuronal nicotinic acetylcholine Apisa7-2 subunit - Apis mellifera (Honeybee) Length = 461 Score = 55.6 bits (128), Expect = 2e-06 Identities = 33/129 (25%), Positives = 56/129 (43%), Gaps = 3/129 (2%) Frame = +2 Query: 167 IVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPD 343 +V L+LH ++ E + + W D L WNA E+ G V R+WRPD Sbjct: 33 VVFGLSLH-HIIDVDEKNQILTTNCWVTQIWTDHHLKWNASEFAGIRVIRVPYNRVWRPD 91 Query: 344 VVLLNAAATTAGDYALRARV--SNNGSVSWIKRLDISTPISMQLDSWPNDMQTCTFKFGS 517 +L N A + V S+ G V W+ + + ++ +P D Q C K+ S Sbjct: 92 TILYNNADPQYSSAVINTNVIVSHTGEVVWLSHGIFRSSCDIDVEFFPFDEQRCVLKWAS 151 Query: 518 RMHNSDEMD 544 ++ +++ Sbjct: 152 WTYDGYQLE 160 >UniRef50_Q17BK9 Cluster: Nicotinic acetylcholine receptor, putative; n=1; Aedes aegypti|Rep: Nicotinic acetylcholine receptor, putative - Aedes aegypti (Yellowfever mosquito) Length = 378 Score = 55.6 bits (128), Expect = 2e-06 Identities = 34/128 (26%), Positives = 61/128 (47%), Gaps = 4/128 (3%) Frame = +2 Query: 185 LHLRHANIRESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNA 361 L L++ +I + + I ++++W D+ L+W+ E G +V S+ +W PD++ A Sbjct: 3 LVLQNFDIDDDRQKLFINVWIRLSWKDQFLTWDPREHNGLKDLMVDSKDIWLPDMMPYAA 62 Query: 362 AATTAGDYAL---RARVSNNGSVSWIKRLDISTPISMQLDSWPNDMQTCTFKFGSRMHNS 532 + D + + V ++G V I D + +WP D CT +FG S Sbjct: 63 YYSNNLDVSCTSPKCSVLSDGEVRCIPACDYHSLCETDFRNWPFDRMNCTIRFGMWAEYS 122 Query: 533 DEMDFVID 556 +E+DF D Sbjct: 123 NEVDFTAD 130 >UniRef50_Q10052 Cluster: Gaba/glycine receptor family (See gbr) protein 3; n=4; Caenorhabditis|Rep: Gaba/glycine receptor family (See gbr) protein 3 - Caenorhabditis elegans Length = 438 Score = 55.6 bits (128), Expect = 2e-06 Identities = 47/170 (27%), Positives = 79/170 (46%), Gaps = 9/170 (5%) Frame = +2 Query: 59 TCAIASAAECE-NATSLSLMIDSLLATYDRDS-PPDSKIVVNLTLHLRH-ANIRESESTV 229 T ++ A CE N+ ++ LL YD+ P ++ + V++ L ++ ++I E S+ Sbjct: 20 TESLVDPAHCEYNSNHRKSILTDLLQDYDKTMVPSNNSVQVSVELTVQDISSISEISSSF 79 Query: 230 RIQADLQMNWIDKRLSWNAGEWGCSTWLVS--SERLWRPDVVLLNAAATTAGDYA---LR 394 W D RL + + L S SERLW P+V +N+ +T + Sbjct: 80 IADVWFSQVWYDPRLEYRNISCKTNLSLDSYVSERLWTPNVCFVNSKSTQVHKSPASNIL 139 Query: 395 ARVSNNGSVSWIK-RLDISTPISMQLDSWPNDMQTCTFKFGSRMHNSDEM 541 + NG+V W+ R+ +S P S +L +P D Q C F S +N E+ Sbjct: 140 LIIYPNGTV-WLNYRVQVSAPCSFELSRFPIDAQECHLVFESYSYNIAEV 188 >UniRef50_A7RS32 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 325 Score = 55.6 bits (128), Expect = 2e-06 Identities = 42/152 (27%), Positives = 68/152 (44%), Gaps = 12/152 (7%) Frame = +2 Query: 125 LLATYDRDSPP----DSKIVVNLTLHLRHA-NIRESESTVRIQADLQMNWIDKRLSWNAG 289 L TY++D P D + V L L L ++ + T+ + ++ W D RL WN Sbjct: 20 LFRTYNKDVLPKETLDKGVPVRLDLALNQIIDVNKRAQTMTVVIWVRQYWRDPRLRWNVS 79 Query: 290 EW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYAL------RARVSNNGSVSWIKRLDIS 448 + G ++ + RLW PD+ L N A DY L +++ G VS Sbjct: 80 AYDGVDNIVIKASRLWLPDITLYNNA---RDDYKLDKESQHSLTITSRGGVSRFFPTIYK 136 Query: 449 TPISMQLDSWPNDMQTCTFKFGSRMHNSDEMD 544 + ++ + +P D QTC K GS +N E++ Sbjct: 137 SSCALNIRHFPFDDQTCILKLGSWSYNVFEVN 168 >UniRef50_UPI000058896A Cluster: PREDICTED: similar to cholinergic receptor neuronal nicotinic alpha protein 2; n=5; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to cholinergic receptor neuronal nicotinic alpha protein 2 - Strongylocentrotus purpuratus Length = 329 Score = 55.2 bits (127), Expect = 2e-06 Identities = 35/108 (32%), Positives = 57/108 (52%), Gaps = 3/108 (2%) Frame = +2 Query: 203 NIRESESTVRIQADLQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLLNA--AATT 373 NIR S S +R +M+W+D R+ WN E+G S + V S ++ PD+ L N+ + T Sbjct: 39 NIRMSLSNLR-----EMHWVDPRMVWNPLEYGNISKFRVHSSEVFVPDITLYNSHSPSKT 93 Query: 374 AGDYALRARVSNNGSVSWIKRLDISTPISMQLDSWPNDMQTCTFKFGS 517 D + ++N+G+V + + I S+ L +P D C K+GS Sbjct: 94 MSD-DISTLMTNHGTVYYTPPVAIEAACSLDLKDYPYDSHICRLKWGS 140 >UniRef50_O17848 Cluster: Putative uncharacterized protein acr-18; n=2; Caenorhabditis|Rep: Putative uncharacterized protein acr-18 - Caenorhabditis elegans Length = 510 Score = 55.2 bits (127), Expect = 2e-06 Identities = 31/116 (26%), Positives = 55/116 (47%), Gaps = 3/116 (2%) Frame = +2 Query: 206 IRESESTVRIQADLQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLLNAAATTA-- 376 + E + V I L++ WID+ L+W+ ++G S V + ++W+PDV++ N A Sbjct: 69 VDERDQIVNIYCWLELYWIDETLTWDPKKFGNLSRIHVPAHKIWKPDVLVYNNANMNVEE 128 Query: 377 GDYALRARVSNNGSVSWIKRLDISTPISMQLDSWPNDMQTCTFKFGSRMHNSDEMD 544 + A V N G V + + ++ L +P D Q C F S + ++D Sbjct: 129 NEMETNAIVDNTGRVMLFRSMITDISCNLNLQQFPFDQQICFVTFASWSMDGSKLD 184 >UniRef50_A7RS33 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 460 Score = 55.2 bits (127), Expect = 2e-06 Identities = 39/149 (26%), Positives = 68/149 (45%), Gaps = 9/149 (6%) Frame = +2 Query: 125 LLATYDRDSPP----DSKIVVNLTLHLRHA-NIRESESTVRIQADLQMNWIDKRLSWNAG 289 LLA Y R+ P D I + + L ++ E T+ +++ W D RL WN Sbjct: 9 LLANYSRNIIPQKYKDIPIKIKFDIALNQIIDLDERLQTITTIVWVRLYWTDFRLRWNHT 68 Query: 290 EWG-CSTWLVSSERLWRPDVVLLNAAATT---AGDYALRARVSNNGSVSWIKRLDISTPI 457 ++G +++ S +LW PD+ L N A + V+++GS+ W + Sbjct: 69 KYGGIKSFVTPSRQLWLPDITLYNNANDNYEKEKEEYYGLTVNSDGSIGWYYPTIFKSSC 128 Query: 458 SMQLDSWPNDMQTCTFKFGSRMHNSDEMD 544 ++ + +P D Q C KFGS ++ +D Sbjct: 129 TIDVTYFPFDDQKCILKFGSWSYHGLSLD 157 >UniRef50_Q21645 Cluster: Acetylcholine receptor protein 10; n=2; Caenorhabditis|Rep: Acetylcholine receptor protein 10 - Caenorhabditis elegans Length = 510 Score = 54.8 bits (126), Expect = 3e-06 Identities = 32/113 (28%), Positives = 53/113 (46%), Gaps = 4/113 (3%) Frame = +2 Query: 227 VRIQADLQMNWIDKRLSWNAGEWGCST---WLVSSERLWRPDVVLLNAAATTA-GDYALR 394 + + A L+ W+D RL W+ ++ T + ++WRPD++L N+A+ + Sbjct: 12 IEVNAWLKYVWMDYRLQWDPLQYDNITSIRFAGGENQIWRPDILLYNSASEDFDSSFKSN 71 Query: 395 ARVSNNGSVSWIKRLDISTPISMQLDSWPNDMQTCTFKFGSRMHNSDEMDFVI 553 V N G V+WI M + +P D Q C KFGS ++ +D I Sbjct: 72 EVVYNTGEVNWIPPGIFRASCKMDITYFPFDDQVCYLKFGSWTYHGLALDLSI 124 >UniRef50_A7S2N9 Cluster: Predicted protein; n=3; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 545 Score = 54.8 bits (126), Expect = 3e-06 Identities = 35/131 (26%), Positives = 70/131 (53%), Gaps = 5/131 (3%) Frame = +2 Query: 167 IVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPD 343 +V+ +++H + ++ E + ++ ++ W + L WN +G + VS ++W PD Sbjct: 77 VVLGMSVH-QIIDVYEKDQIIKTSFWVRQIWYNPFLRWNETFYGGIKEINVSPLQVWTPD 135 Query: 344 VVLLNAA-ATTAG---DYALRARVSNNGSVSWIKRLDISTPISMQLDSWPNDMQTCTFKF 511 +VL N A A+T G ++ R VS++G W+ + S+ ++++ +P D Q C+ KF Sbjct: 136 LVLYNNADASTDGSLENFKTRIIVSSDGKNMWLAPVIFSSSCTIKIKYFPFDDQYCSLKF 195 Query: 512 GSRMHNSDEMD 544 GS + +D Sbjct: 196 GSWTFDGFHLD 206 >UniRef50_A7S2J7 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 462 Score = 54.8 bits (126), Expect = 3e-06 Identities = 40/150 (26%), Positives = 71/150 (47%), Gaps = 10/150 (6%) Frame = +2 Query: 98 TSLSLMIDSLLATYDRDSPP---DS-KIVVNLTLHLRHANIRESEST-VRIQADLQMNWI 262 T+ ++ L YD + P DS K+ V +L L S+S V + ++ W Sbjct: 36 TAEKRLLADLFRNYDSEVRPVFNDSDKVNVEFSLSLIQIIAVNSKSQLVTVSVWIRQKWT 95 Query: 263 DKRLSWNAGEWG-CSTWLVSSERLWRPDVVLLNAAATT-AGD---YALRARVSNNGSVSW 427 + L+WN ++G + ++ ++W PD++L N A T AG Y S++G+ W Sbjct: 96 NPMLAWNTSKYGGIESVNLNPAKVWIPDIILYNNADETYAGGLEKYKTSVIASSDGTQEW 155 Query: 428 IKRLDISTPISMQLDSWPNDMQTCTFKFGS 517 ++ ++ + +P D Q C+ KFGS Sbjct: 156 NSPASFTSTCNINVRYFPFDSQNCSLKFGS 185 >UniRef50_Q60S81 Cluster: Neuronal acetylcholine receptor subunit eat-2 precursor; n=1; Caenorhabditis briggsae|Rep: Neuronal acetylcholine receptor subunit eat-2 precursor - Caenorhabditis briggsae Length = 477 Score = 54.8 bits (126), Expect = 3e-06 Identities = 37/131 (28%), Positives = 63/131 (48%), Gaps = 3/131 (2%) Frame = +2 Query: 173 VNLTLHLRH-ANIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDV 346 V L L L+ ++ E + + Q W D ++ W+ E+G T L + LW+PD+ Sbjct: 50 VKLRLILQQLVDVDEKNQVITLVVWTQYTWNDYKMKWSPEEYGNITSLQIPFGTLWKPDI 109 Query: 347 VLLNAAATTA-GDYALRARVSNNGSVSWIKRLDISTPISMQLDSWPNDMQTCTFKFGSRM 523 +L N+A + + VSN+G+V + + S+ + +P D Q C KFGS Sbjct: 110 LLFNSANEHFDSSFPVNMVVSNDGNVLFAPPGIMQFSCSLSMTWFPYDEQVCYLKFGSWT 169 Query: 524 HNSDEMDFVID 556 + ++D ID Sbjct: 170 YGK-KLDLRID 179 >UniRef50_UPI00015B6212 Cluster: PREDICTED: similar to nicotinic acetylcholine receptor alpha9 subunit; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to nicotinic acetylcholine receptor alpha9 subunit - Nasonia vitripennis Length = 443 Score = 54.4 bits (125), Expect = 4e-06 Identities = 46/174 (26%), Positives = 76/174 (43%), Gaps = 8/174 (4%) Frame = +2 Query: 59 TCAIASAAECENATSLSLMIDSLLATYDRDSPP--DSKIVVNLTLHLRHANI--RESEST 226 TC++A+A + L D YD P K N+++H I + ST Sbjct: 29 TCSLAAAKSPHLRLNRYLFCD-----YDITVRPVIHHKNATNISIHFDPLRIDFMDESST 83 Query: 227 VRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA---ATTAGDYALR 394 + +W+D+ L+WN ++ G + V S ++W PD+ L N+A T G ++ Sbjct: 84 FILHTWNTWSWMDEFLTWNPKDFDGINETRVESAKIWTPDLALYNSADMTETQIGIPSVP 143 Query: 395 ARVSNNGSVSWIKRLDISTPISMQLDSWPNDMQTCTFKFGSRMHNSDEMDFVID 556 + N+G + I + T + WP D QTC + S N+ +D ID Sbjct: 144 CILVNDGQLVCIAPVKYVTHCTTDFTYWPYDEQTCNIRLSS--WNNHALDINID 195 >UniRef50_UPI0000F2C37E Cluster: PREDICTED: similar to CHRNG protein; n=1; Monodelphis domestica|Rep: PREDICTED: similar to CHRNG protein - Monodelphis domestica Length = 497 Score = 54.4 bits (125), Expect = 4e-06 Identities = 41/145 (28%), Positives = 68/145 (46%), Gaps = 10/145 (6%) Frame = +2 Query: 113 MIDSLLATYDRDSPP---DSKIVVNLTLHLRHANI---RESESTVRIQADLQMNWIDKRL 274 +++ L+ Y+ + P DS I+ N+TL L N+ E E + ++M W D RL Sbjct: 27 LLNDLMRNYNPNLRPAEVDSDII-NVTLKLTLTNLISLNEREEALTTNVWIEMQWCDYRL 85 Query: 275 SWNAGEWGCSTWL--VSSERLWRPDVVLLNAAATTAGDYAL--RARVSNNGSVSWIKRLD 442 W+ ++ W+ + S +WRPD+VL N + AL VS NG + W+ Sbjct: 86 RWDPRDYE-DVWVLRIPSTMVWRPDIVLEN-NVDGVFEVALYCNVLVSPNGCIYWLPPAI 143 Query: 443 ISTPISMQLDSWPNDMQTCTFKFGS 517 + + + +P D Q C+ F S Sbjct: 144 FRSSCPVTVTYFPFDWQNCSLVFQS 168 >UniRef50_A7RNI2 Cluster: Predicted protein; n=3; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 485 Score = 54.4 bits (125), Expect = 4e-06 Identities = 32/154 (20%), Positives = 74/154 (48%), Gaps = 10/154 (6%) Frame = +2 Query: 113 MIDSLLATYDRDSPP--DSKIVVNLTLHLRHA---NIRESESTVRIQADLQMNWIDKRLS 277 +++ L Y++++ P + + + + +A N+ + ++ + + W++ L+ Sbjct: 30 LLNDLFKDYNKEARPVLNKSEAIEVQFDMAYAQLINLNSKDQILQSKVWFRQRWVNPFLT 89 Query: 278 WNAGEWGCSTWL-VSSERLWRPDVVLLN--AAATTAGDYAL--RARVSNNGSVSWIKRLD 442 W+ +G T + V+ +W+PD+VL + T Y RA + +NG W + Sbjct: 90 WDPKMYGGLTSINVNPNMIWKPDIVLYHNIGFGETGAIYKFDTRATIMHNGYTEWFAPTE 149 Query: 443 ISTPISMQLDSWPNDMQTCTFKFGSRMHNSDEMD 544 I + ++ + +P D Q C KFGS ++ +++ Sbjct: 150 IHSICAIDITYFPFDEQFCKMKFGSWSYSGRQLN 183 >UniRef50_A7RFJ2 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 278 Score = 54.4 bits (125), Expect = 4e-06 Identities = 33/130 (25%), Positives = 62/130 (47%), Gaps = 2/130 (1%) Frame = +2 Query: 167 IVVNLTLHLRH-ANIRESESTVRIQADLQMNWIDKRLSWNAGEWGCST-WLVSSERLWRP 340 I V + HL A + E E +++ ++ W + L WN E+G T +V + +W P Sbjct: 31 ITVVFSAHLLGLAKVNEKEQSIKTHLWIKEEWYNPFLMWNPEEFGNITEIIVPANMIWVP 90 Query: 341 DVVLLNAAATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDSWPNDMQTCTFKFGSR 520 D++L N +T + + ++ NG+ +W +T + + +P D QTC F S Sbjct: 91 DIILYNKGSTL---FNTKVIIAFNGNNTWRSPAIYNTMCVLDVKYFPFDEQTCDLVFASW 147 Query: 521 MHNSDEMDFV 550 + +++ V Sbjct: 148 TRDISKLNLV 157 >UniRef50_P31644 Cluster: Gamma-aminobutyric acid receptor subunit alpha-5 precursor (GABA(A) receptor subunit alpha-5); n=86; Euteleostomi|Rep: Gamma-aminobutyric acid receptor subunit alpha-5 precursor (GABA(A) receptor subunit alpha-5) - Homo sapiens (Human) Length = 462 Score = 54.4 bits (125), Expect = 4e-06 Identities = 39/161 (24%), Positives = 72/161 (44%), Gaps = 7/161 (4%) Frame = +2 Query: 89 ENATSLSLMIDSLLATYDRDSPPD--SKIV-VNLTLHLRHAN-IRESESTVRIQADLQMN 256 +N T + ++D LL YD P +I V +++ + ++E I + + Sbjct: 44 DNITIFTRILDGLLDGYDNRLRPGLGERITQVRTDIYVTSFGPVSDTEMEYTIDVFFRQS 103 Query: 257 WIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSW 427 W D+RL + + + ++W PD N + A + R+ ++G++ + Sbjct: 104 WKDERLRFKGPMQRLPLNNLLASKIWTPDTFFHNGKKSIAHNMTTPNKLLRLEDDGTLLY 163 Query: 428 IKRLDISTPISMQLDSWPNDMQTCTFKFGSRMHNSDEMDFV 550 RL IS MQL+ +P D C KFGS + + E+ +V Sbjct: 164 TMRLTISAECPMQLEDFPMDAHACPLKFGSYAYPNSEVVYV 204 >UniRef50_Q9XTY8 Cluster: Putative uncharacterized protein lgc-25; n=3; Caenorhabditis|Rep: Putative uncharacterized protein lgc-25 - Caenorhabditis elegans Length = 502 Score = 54.0 bits (124), Expect = 5e-06 Identities = 30/128 (23%), Positives = 56/128 (43%), Gaps = 4/128 (3%) Frame = +2 Query: 173 VNLTLHLRHAN-IRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVV 349 VN+ L + H + E E T + + WID+ + W+A + + +S+ LW+P + Sbjct: 54 VNVFLSIAHVEKVDEHEQTALVHGHIWATWIDEYMQWDAKKENVTKLTISAHSLWQPALA 113 Query: 350 LLNAAATTAGDY---ALRARVSNNGSVSWIKRLDISTPISMQLDSWPNDMQTCTFKFGSR 520 L N+A + A+ A V + G V +WP D Q+C Sbjct: 114 LYNSARGNSWHLYMGAMPATVYSTGKVWSTGTFSFYVTCQFDFTNWPFDQQSCPIVIADW 173 Query: 521 MHNSDEMD 544 ++N ++++ Sbjct: 174 VYNLNQVN 181 >UniRef50_Q6TMY0 Cluster: Nicotinic acetylcholine receptor non-alpha subunit precursor; n=3; Schistosoma|Rep: Nicotinic acetylcholine receptor non-alpha subunit precursor - Schistosoma bovis (Blood fluke) Length = 740 Score = 54.0 bits (124), Expect = 5e-06 Identities = 25/102 (24%), Positives = 51/102 (50%), Gaps = 2/102 (1%) Frame = +2 Query: 245 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGD-YALRARVSNNGS 418 L + W D WNA ++ + + ER+W+PD++L N+A+ + + V N G+ Sbjct: 88 LDLKWSDYHFHWNASDYENIRQINLPPERIWKPDILLYNSASEKFDQIFPTKVIVRNTGN 147 Query: 419 VSWIKRLDISTPISMQLDSWPNDMQTCTFKFGSRMHNSDEMD 544 + W+ + ++++ +P D Q C K G+ + + +D Sbjct: 148 IQWVPPGLFHSICDIEVNWFPFDSQNCIMKLGTWTYQGNTVD 189 >UniRef50_UPI00015A4976 Cluster: 5-hydroxytryptamine receptor 3 subunit C; n=2; Danio rerio|Rep: 5-hydroxytryptamine receptor 3 subunit C - Danio rerio Length = 410 Score = 53.6 bits (123), Expect = 7e-06 Identities = 30/140 (21%), Positives = 61/140 (43%) Frame = +2 Query: 161 SKIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRP 340 + + V+LTL+ + E + ++ W + L+W+ E G + E++W P Sbjct: 10 TNVTVDLTLY-GILGVNEKSQVLETYLWVRTRWQIEGLTWDPAECGTKKISLPREKIWFP 68 Query: 341 DVVLLNAAATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDSWPNDMQTCTFKFGSR 520 D+V+ V++ G V + I + + + ++P D Q CT+ F S Sbjct: 69 DIVINEFMDENRAPDTYYVYVTSTGQVIDGRPFHIISSCKLDIYTFPFDFQNCTYTFNSY 128 Query: 521 MHNSDEMDFVIDKRIYSMFE 580 H+ D++ K + +F+ Sbjct: 129 KHSRDDVQLFFYKPVKDIFK 148 >UniRef50_Q7PJX0 Cluster: ENSANGP00000022703; n=1; Anopheles gambiae str. PEST|Rep: ENSANGP00000022703 - Anopheles gambiae str. PEST Length = 223 Score = 53.6 bits (123), Expect = 7e-06 Identities = 41/171 (23%), Positives = 79/171 (46%), Gaps = 13/171 (7%) Frame = +2 Query: 71 ASAAECENATSL----SLMIDSLLAT-YDRDSPP--DSKIVVNLTL--HLRHANIRESES 223 A++ EC + L + + D+LL Y + P D VN+T+ ++ ES++ Sbjct: 28 AASLECNSEKQLENRENQLKDTLLCKGYRTNVRPRKDHTQTVNVTVAYYVLTYEFEESDN 87 Query: 224 TVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNA--AATTAGDYA-L 391 +++ +++ W D+ L WN+ EW G + SE +W PD ++ + A Sbjct: 88 LLQLGVWMELQWTDEYLRWNSTEWSGIERLAIGSEEIWMPDFRHFSSYYNPEDLNECANP 147 Query: 392 RARVSNNGSVSWIKRLDISTPISMQLDSWPNDMQTCTFKFGSRMHNSDEMD 544 + V+ NG+V + ++ WP D+ C +G+ ++ DE+D Sbjct: 148 KCSVAPNGTVVCLPVCGMNAKCDADYSRWPFDVHRCNLWYGTWANSMDEVD 198 >UniRef50_Q86YW4 Cluster: Ligand-gated ion channel subunit; n=10; Theria|Rep: Ligand-gated ion channel subunit - Homo sapiens (Human) Length = 411 Score = 53.6 bits (123), Expect = 7e-06 Identities = 28/101 (27%), Positives = 48/101 (47%) Frame = +2 Query: 245 LQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVS 424 L+++W+D RL+WN + E LW P + +L A D + +ARV +G V Sbjct: 86 LRLSWLDTRLAWNTSAHPRHAITLPWESLWTPRLTILEALWVDWRDQSPQARVDQDGHVK 145 Query: 425 WIKRLDISTPISMQLDSWPNDMQTCTFKFGSRMHNSDEMDF 547 L T + +L +P D C+ F + + + E++F Sbjct: 146 LNLALTTETNCNFELLHFPRDHSNCSLSFYALSNTAMELEF 186 >UniRef50_Q2XWK4 Cluster: Nicotinic acetylcholine receptor subunit type I; n=1; Lymnaea stagnalis|Rep: Nicotinic acetylcholine receptor subunit type I - Lymnaea stagnalis (Great pond snail) Length = 527 Score = 53.2 bits (122), Expect = 9e-06 Identities = 37/154 (24%), Positives = 69/154 (44%), Gaps = 10/154 (6%) Frame = +2 Query: 113 MIDSLLATYDRDSPPDSKIVV---NLTLH-----LRHANIRESESTVRIQADLQMNWIDK 268 +I SLL Y+R ++ N+T+ ++ ++ ES ++ + W D Sbjct: 62 LISSLLKKYERQGKQGRPVINTSDNMTVLFGLSLIQILDVDESNQVLKASMWYRYEWNDM 121 Query: 269 RLSWN-AGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYA-LRARVSNNGSVSWIKRLD 442 L W+ A + + S +W PD++L N A + V NNG + W+ + Sbjct: 122 LLKWDPAMHDDIQSIRIPSSMIWLPDILLYNFADDRLREQRDALCIVQNNGDIQWMPQAI 181 Query: 443 ISTPISMQLDSWPNDMQTCTFKFGSRMHNSDEMD 544 + + S +P D+Q+C KFGS +N +++ Sbjct: 182 LRSSCSFDTKYFPFDVQSCWLKFGSWTYNGFKLN 215 >UniRef50_P36544 Cluster: Neuronal acetylcholine receptor subunit alpha-7 precursor; n=65; Euteleostomi|Rep: Neuronal acetylcholine receptor subunit alpha-7 precursor - Homo sapiens (Human) Length = 502 Score = 53.2 bits (122), Expect = 9e-06 Identities = 35/135 (25%), Positives = 64/135 (47%), Gaps = 2/135 (1%) Frame = +2 Query: 146 DSPPDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSS 322 DS P + + +L+L L+ ++ E + LQM+W D L WN E+ G T Sbjct: 47 DSQPLT-VYFSLSL-LQIMDVDEKNQVLTTNIWLQMSWTDHYLQWNVSEYPGVKTVRFPD 104 Query: 323 ERLWRPDVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDSWPNDMQTC 499 ++W+PD++L N+A + V+++G ++ + + + +P D+Q C Sbjct: 105 GQIWKPDILLYNSADERFDATFHTNVLVNSSGHCQYLPPGIFKSSCYIDVRWFPFDVQHC 164 Query: 500 TFKFGSRMHNSDEMD 544 KFGS + +D Sbjct: 165 KLKFGSWSYGGWSLD 179 >UniRef50_UPI0000E48474 Cluster: PREDICTED: similar to nicotinic acetylcholine receptor subunit type G, partial; n=1; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to nicotinic acetylcholine receptor subunit type G, partial - Strongylocentrotus purpuratus Length = 452 Score = 52.8 bits (121), Expect = 1e-05 Identities = 33/117 (28%), Positives = 56/117 (47%), Gaps = 7/117 (5%) Frame = +2 Query: 212 ESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYA 388 E + I ++ +W D++L W+ + G + + +W PDV L + A + DY Sbjct: 2 ERNQVLTINVWIEQHWDDEKLVWDPDAYEGIEILRIPATEIWLPDVTLYDNA--DSNDYV 59 Query: 389 LRARVSN-----NGSVS-WIKRLDISTPISMQLDSWPNDMQTCTFKFGSRMHNSDEM 541 +R SN +G V W K + + + + +P D Q C+ KFGS +NS +M Sbjct: 60 AHSRQSNALVNADGRVDLWSKPALVKSTCKIDVKFFPFDEQMCSMKFGSWTYNSFQM 116 >UniRef50_Q6F6K3 Cluster: Acetylcholine receptor protein 17, isoform b; n=4; Caenorhabditis|Rep: Acetylcholine receptor protein 17, isoform b - Caenorhabditis elegans Length = 515 Score = 52.8 bits (121), Expect = 1e-05 Identities = 32/152 (21%), Positives = 72/152 (47%), Gaps = 9/152 (5%) Frame = +2 Query: 113 MIDSLLATYDRDSPP---DSKIVVNLTLHLRHANIR---ESESTVRIQADLQMNWIDKRL 274 +I L Y ++ P +S N+T+ L I+ E++ + + ++ W D+ L Sbjct: 27 LIKYLFRDYHKELRPVKDESSGPTNVTVQLYFKQIQKVHENDQIITLYCWIEEYWQDEFL 86 Query: 275 SWNAGEWG-CSTWLVSSERLWRPDVVLLNAAATTAGDYALR--ARVSNNGSVSWIKRLDI 445 +WN ++G + V SE +W+PD+++ N A + ++ ++ + G +S + + Sbjct: 87 TWNPSDFGNIKSLHVPSEMIWKPDLLVYNNANMNIKENEMQTNVQIEHTGKISLFRAIIT 146 Query: 446 STPISMQLDSWPNDMQTCTFKFGSRMHNSDEM 541 +Q++ +P D Q C S ++ ++ Sbjct: 147 DITCDLQMEKFPYDQQICFIMLASWSYDGSQI 178 >UniRef50_Q18556 Cluster: Putative uncharacterized protein acr-9; n=2; Caenorhabditis|Rep: Putative uncharacterized protein acr-9 - Caenorhabditis elegans Length = 534 Score = 52.8 bits (121), Expect = 1e-05 Identities = 33/135 (24%), Positives = 66/135 (48%), Gaps = 5/135 (3%) Frame = +2 Query: 167 IVVNLTLHLRHA-NIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWL---VSSERLW 334 +VV++ ++L+ ++ E + + A ++ W D +L W+ E+G + ++ +W Sbjct: 53 LVVSVKIYLQQILDVDEKNQVITLVAWIEYQWTDYKLKWDPSEYGGIKDIRIPGNANAIW 112 Query: 335 RPDVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDSWPNDMQTCTFKF 511 +PDV+L N+A Y + VS G V + + + + +P D Q C KF Sbjct: 113 KPDVLLYNSADENFDSTYPVNYVVSYTGDVLQVPPGILKLSCKIDITYFPFDDQICHLKF 172 Query: 512 GSRMHNSDEMDFVID 556 GS ++ + +D I+ Sbjct: 173 GSWTYSGNFIDLRIN 187 >UniRef50_Q2XWK7 Cluster: Nicotinic acetylcholine receptor subunit type F; n=1; Lymnaea stagnalis|Rep: Nicotinic acetylcholine receptor subunit type F - Lymnaea stagnalis (Great pond snail) Length = 488 Score = 52.4 bits (120), Expect = 2e-05 Identities = 29/101 (28%), Positives = 51/101 (50%), Gaps = 2/101 (1%) Frame = +2 Query: 248 QMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYA-LRARVSNNGSV 421 + W D L W+ ++ T + + SE +W PD++L N A + VS++GS+ Sbjct: 97 EYTWSDVLLKWDIEQYDNITDVRIPSEHIWLPDILLYNFADDRLKEQRNALVVVSHDGSL 156 Query: 422 SWIKRLDISTPISMQLDSWPNDMQTCTFKFGSRMHNSDEMD 544 W+ + + + + +P D QTC KFGS +N ++D Sbjct: 157 LWMPQAILRSSCAFNTLYFPFDEQTCVLKFGSWSYNGFKLD 197 >UniRef50_Q0GQQ6 Cluster: Cys-loop ligand-gated ion channel subunit; n=3; Endopterygota|Rep: Cys-loop ligand-gated ion channel subunit - Apis mellifera (Honeybee) Length = 510 Score = 52.4 bits (120), Expect = 2e-05 Identities = 35/147 (23%), Positives = 66/147 (44%), Gaps = 8/147 (5%) Frame = +2 Query: 101 SLSLMIDSLLATYDRDSPPD----SKIVVNLTLHLRHAN-IRESESTVRIQADLQMNWID 265 ++++++++LL Y+ + P + VV + +R + E + + + +W D Sbjct: 36 NITMVLENLLMNYENNQLPTHGKGTPTVVKTNILIRSMGPVSELDMDYSMDCYFRQSWRD 95 Query: 266 KRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKR 436 RLS+ S + ER+WRPD N + + R+S +G + + R Sbjct: 96 SRLSFLGPIKSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRISQDGDILYSMR 155 Query: 437 LDISTPISMQLDSWPNDMQTCTFKFGS 517 L I M+L ++P D Q+C GS Sbjct: 156 LTIKAKCPMELRNFPMDRQSCPLILGS 182 >UniRef50_A7S2P0 Cluster: Predicted protein; n=4; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 541 Score = 52.4 bits (120), Expect = 2e-05 Identities = 30/132 (22%), Positives = 64/132 (48%), Gaps = 6/132 (4%) Frame = +2 Query: 167 IVVNLTLHLRHA-NIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRP 340 + V L L L ++ E + + ++ W + ++WN E+G + + LW+P Sbjct: 94 VTVKLGLTLNQIMDVIEKFELLSVSLYVRQKWENPLVAWNKSEYGGIVQVNLDPSTLWKP 153 Query: 341 DVVLLNAAAT----TAGDYALRARVSNNGSVSWIKRLDISTPISMQLDSWPNDMQTCTFK 508 D+ L N A + + + + +V+ +G+ +W+ +T + + +P D Q C K Sbjct: 154 DIYLYNNADSGYDGSLYGFTAKIKVNYSGTNTWLAPKIFTTSCKINVKYFPFDQQECRLK 213 Query: 509 FGSRMHNSDEMD 544 FGS ++++ +D Sbjct: 214 FGSWTYDANSVD 225 >UniRef50_UPI00006A0B5C Cluster: Gamma-aminobutyric-acid receptor subunit alpha-3 precursor (GABA(A) receptor subunit alpha-3).; n=2; Xenopus tropicalis|Rep: Gamma-aminobutyric-acid receptor subunit alpha-3 precursor (GABA(A) receptor subunit alpha-3). - Xenopus tropicalis Length = 465 Score = 52.0 bits (119), Expect = 2e-05 Identities = 29/122 (23%), Positives = 60/122 (49%), Gaps = 3/122 (2%) Frame = +2 Query: 191 LRHANIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAAT 370 ++ N+ E T+ + + +W+D+RL ++ + + ++W PD N + Sbjct: 76 VKQVNMPSLEYTIDVF--FRQSWLDERLKFDGPIRTLPLNNLLASKIWTPDTFFHNGKKS 133 Query: 371 TAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDSWPNDMQTCTFKFGSRMHNSDEM 541 A + R+ +NG++ + RL I +M L+ +P D+ C KFGS M+ ++++ Sbjct: 134 VAHNMTTPNKLLRLIDNGTLLYTMRLTIHAECTMHLEDFPMDVHACPLKFGSCMYCNEQV 193 Query: 542 DF 547 F Sbjct: 194 SF 195 >UniRef50_Q9GQU9 Cluster: Nicotinic acetylcholine receptor-like subunit ACR-12; n=2; Caenorhabditis|Rep: Nicotinic acetylcholine receptor-like subunit ACR-12 - Caenorhabditis elegans Length = 573 Score = 52.0 bits (119), Expect = 2e-05 Identities = 33/120 (27%), Positives = 55/120 (45%), Gaps = 2/120 (1%) Frame = +2 Query: 191 LRHANIRESESTVRIQADLQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLLNAAA 367 +R ++ E + L+M W D +L+W ++G T + S+ +W PD+VL N AA Sbjct: 72 IRIIDVDEKNQVLTTNLWLEMKWNDAKLTWTPEKYGGLKTLHIPSDFIWTPDLVLYNNAA 131 Query: 368 TTAGDYALR-ARVSNNGSVSWIKRLDISTPISMQLDSWPNDMQTCTFKFGSRMHNSDEMD 544 L A V+ G+V W + + + +P D Q C KFG+ + +D Sbjct: 132 GDPDITILTDALVTFEGNVYWQPPAIYKSFCPIDVTWFPYDSQKCEMKFGTWTYTGRYVD 191 >UniRef50_Q6TMY3 Cluster: Nicotinic acetylcholine receptor alpha subunit precursor; n=4; Schistosoma|Rep: Nicotinic acetylcholine receptor alpha subunit precursor - Schistosoma haematobium (Blood fluke) Length = 714 Score = 52.0 bits (119), Expect = 2e-05 Identities = 28/103 (27%), Positives = 51/103 (49%), Gaps = 2/103 (1%) Frame = +2 Query: 245 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAG-DYALRARVSNNGS 418 + + W D WN E+G T L + +WRPD++L N A + + ++G+ Sbjct: 84 MDLIWNDYHFLWNPKEFGNITTLNLPYTAVWRPDILLYNCADEKFDRTFPTNTIIKHDGT 143 Query: 419 VSWIKRLDISTPISMQLDSWPNDMQTCTFKFGSRMHNSDEMDF 547 V W+ + ++ + +P D Q+C KFGS + D+++F Sbjct: 144 VQWMPPGLFKSTCNIDILWFPFDEQSCILKFGSWTYYGDQINF 186 >UniRef50_Q4V4V5 Cluster: IP12579p; n=6; Endopterygota|Rep: IP12579p - Drosophila melanogaster (Fruit fly) Length = 612 Score = 52.0 bits (119), Expect = 2e-05 Identities = 35/147 (23%), Positives = 64/147 (43%), Gaps = 8/147 (5%) Frame = +2 Query: 101 SLSLMIDSLLATYDRDSPPDS----KIVVNLTLHLRHAN-IRESESTVRIQADLQMNWID 265 ++S+++++LL Y++ P VV + +R + E + + + W D Sbjct: 107 NISMILENLLKRYEQSQLPTHGQGVPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRD 166 Query: 266 KRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKR 436 KRLS+ S + +++WRPD N + + R+ NG + + R Sbjct: 167 KRLSFKGPIKSLSLSIKMLDKIWRPDTYFYNGKHSQIHMITVPNKLLRLDQNGGILYSMR 226 Query: 437 LDISTPISMQLDSWPNDMQTCTFKFGS 517 L I M+L ++P D Q+C GS Sbjct: 227 LTIKATCPMELQNFPMDRQSCPLVIGS 253 >UniRef50_A7RND6 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 254 Score = 52.0 bits (119), Expect = 2e-05 Identities = 28/99 (28%), Positives = 49/99 (49%), Gaps = 1/99 (1%) Frame = +2 Query: 257 WIDKRLSWNAGEWGCSTWLVSS-ERLWRPDVVLLNAAATTAGDYALRARVSNNGSVSWIK 433 W D RL+WN E+G ++L +++W PD++L A G RA +++ G V + Sbjct: 3 WKDPRLTWNPTEFGNISYLTMKVDKIWSPDMML--TLADIPGSLEFRAIITHEGLVKIFQ 60 Query: 434 RLDISTPISMQLDSWPNDMQTCTFKFGSRMHNSDEMDFV 550 IST + + +P D TC + G N+ ++ + Sbjct: 61 PTSISTTCEVNIAFYPFDEHTCFIEIGPWSMNTAAVNVI 99 >UniRef50_UPI0000E473D1 Cluster: PREDICTED: similar to neuronal acetylcholine receptor subunit alpha-9 precursor; n=2; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to neuronal acetylcholine receptor subunit alpha-9 precursor - Strongylocentrotus purpuratus Length = 510 Score = 51.6 bits (118), Expect = 3e-05 Identities = 26/110 (23%), Positives = 57/110 (51%), Gaps = 2/110 (1%) Frame = +2 Query: 212 ESESTVRIQADLQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLL-NAAATTAGDY 385 E + V++ + +W D+ L W+ ++G T S + +W+PD+ L+ N ++ Sbjct: 140 ERKQHVQLSGWRRQDWRDEFLQWDPDDYGGLETITFSKDGIWKPDITLIENVNQDFINEF 199 Query: 386 ALRARVSNNGSVSWIKRLDISTPISMQLDSWPNDMQTCTFKFGSRMHNSD 535 + V+ +GSV+W + +++ + + +P D QTC + S ++S+ Sbjct: 200 SADVIVTYDGSVTWFTPIILTSACMVGVRYFPFDFQTCQMTYMSWAYDSN 249 >UniRef50_Q67X94 Cluster: Putative uncharacterized protein lgc-2; n=3; Caenorhabditis|Rep: Putative uncharacterized protein lgc-2 - Caenorhabditis elegans Length = 509 Score = 51.6 bits (118), Expect = 3e-05 Identities = 34/153 (22%), Positives = 73/153 (47%), Gaps = 10/153 (6%) Frame = +2 Query: 113 MIDSLLATYDRDSPPDSKIVVNLTLHLRHA-NIRESESTVRIQADLQMNWIDKRLSWNAG 289 + + LL+ ++ ++PPD + V L L H I E + T+ + + +W+D L+W+ Sbjct: 70 LTEYLLSRHNLNAPPDGLLYVEYELELVHILGIDELKQTMTVLIYVDEHWVDPSLTWDPA 129 Query: 290 EWG--CSTWLVSSERLWRPDVVLLNAAATTAGDY-----ALR--ARVSNNGSVSWIKRLD 442 +G TW + +++W PD+++ N + + A+R AR+ NG++ Sbjct: 130 LFGGITKTW-IPLDKIWVPDIIVFNMVKSNRLAHEDLLSAVRAPARIHYNGTIVASHPAV 188 Query: 443 ISTPISMQLDSWPNDMQTCTFKFGSRMHNSDEM 541 + + + +P D Q C + S + +++ Sbjct: 189 HTVSCEINIRHFPLDDQRCAIEIASWAYGQEKI 221 >UniRef50_Q4R170 Cluster: Putative uncharacterized protein; n=1; Caenorhabditis elegans|Rep: Putative uncharacterized protein - Caenorhabditis elegans Length = 404 Score = 51.6 bits (118), Expect = 3e-05 Identities = 32/136 (23%), Positives = 60/136 (44%), Gaps = 3/136 (2%) Frame = +2 Query: 152 PPDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSER 328 PP +I + L++ ++ + E E D + +W D RLSW+ ++G + V + Sbjct: 79 PPRFEITIQLSM-MKLVEVVEPEEKATFLFDYRADWYDTRLSWDPEDYGGINHIYVPRSK 137 Query: 329 LWRPDVVLLNAAATTAGD--YALRARVSNNGSVSWIKRLDISTPISMQLDSWPNDMQTCT 502 +W P+ +++ + D Y A + +NGS+ S M + +P D TC+ Sbjct: 138 VWIPETTIVDCSEIKVFDNEYTRYAWLHSNGSIGMYIASVTSVVCQMDVYKFPMDTHTCS 197 Query: 503 FKFGSRMHNSDEMDFV 550 F + +E V Sbjct: 198 VNFLFMTYQLEEFTIV 213 >UniRef50_A7SLK4 Cluster: Predicted protein; n=2; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 319 Score = 51.6 bits (118), Expect = 3e-05 Identities = 43/164 (26%), Positives = 80/164 (48%), Gaps = 11/164 (6%) Frame = +2 Query: 107 SLMIDSLLATYDRDSPPDSK---IVVNLTLHLRHA-NIRESESTVRIQADLQMNWIDKRL 274 +L++ +LL YDR P SK +VV + +++ + ++E I L+ W D+RL Sbjct: 23 TLVLKNLLEGYDRRIRPGSKGEPVVVYVDMYVSNIWAMQEMNMDFTIDIYLRQYWRDERL 82 Query: 275 SWNAGEWGCSTWLVS--SERLWRPDVVLLNAAAT-----TAGDYALRARVSNNGSVSWIK 433 + G L S ++++W P L T +Y L+ V +GS+ + Sbjct: 83 QFETQTPGAMLTLSSDINKQIWVPSTYFLATKKAYFHDVTTDNYLLQ--VKPDGSLFYSI 140 Query: 434 RLDISTPISMQLDSWPNDMQTCTFKFGSRMHNSDEMDFVIDKRI 565 RL I+T + L +P+D Q+C+ S + S ++ +V ++R+ Sbjct: 141 RLTITTSCRLDLRDFPHDTQSCSLSLESYGYQSTDVLYVWNERL 184 >UniRef50_A6XBS1 Cluster: Amorphous calcium carbonate binding protein 1; n=1; Pinctada fucata|Rep: Amorphous calcium carbonate binding protein 1 - Pinctada fucata (Pearl oyster) Length = 240 Score = 51.6 bits (118), Expect = 3e-05 Identities = 49/171 (28%), Positives = 76/171 (44%), Gaps = 10/171 (5%) Frame = +2 Query: 62 CAIASAAECENATSLSLMIDSLLATYD---RDSPPDSKI-VVNLTLHLRHANIRESEST- 226 C + SA + + ++ LL Y+ R P D VV++ L H + +S+S Sbjct: 16 CVLFSAVVAKCDYPEAKLLKFLLDDYEKLVRPVPKDGNATVVSMGFSLNHIDDYDSDSME 75 Query: 227 VRIQADLQMNWIDKRLSWN--AGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDY--AL 391 ++ A L + W D RL+WN G +G L + +W PDVVLLN + L Sbjct: 76 LKSNAWLSLKWNDPRLTWNKDGGPFGNVKALHLPPSDIWVPDVVLLNGLQPFQPQFPDRL 135 Query: 392 RARVSNNGSVSWIKRLDISTPISMQLDSWPNDMQTCTFKFGSRMHNSDEMD 544 A V + G + I + T + D D TC FKF S ++ E++ Sbjct: 136 TALVKDTGDIYLITPSVLETRCTP--DKADGDKATCRFKFMSWTYDGGEVE 184 >UniRef50_P18505 Cluster: Gamma-aminobutyric acid receptor subunit beta-1 precursor (GABA(A) receptor subunit beta-1); n=104; Euteleostomi|Rep: Gamma-aminobutyric acid receptor subunit beta-1 precursor (GABA(A) receptor subunit beta-1) - Homo sapiens (Human) Length = 474 Score = 51.6 bits (118), Expect = 3e-05 Identities = 40/169 (23%), Positives = 73/169 (43%), Gaps = 7/169 (4%) Frame = +2 Query: 62 CAIASAAECENATSLSLMIDSLLATYDRDSPPD---SKIVVNLTLHLRHAN-IRESESTV 229 C S E N + + +D LL YD PD + V + + + + + E Sbjct: 23 CCAHSTNEPSNMSYVKETVDRLLKGYDIRLRPDFGGPPVDVGMRIDVASIDMVSEVNMDY 82 Query: 230 RIQADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---AR 400 + Q +W DKRLS++ + +++LW PD LN + ++ R Sbjct: 83 TLTMYFQQSWKDKRLSYSGIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIR 142 Query: 401 VSNNGSVSWIKRLDISTPISMQLDSWPNDMQTCTFKFGSRMHNSDEMDF 547 + +G+V + R+ + M L +P D Q CT + S + +D+++F Sbjct: 143 LHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEF 191 >UniRef50_UPI00006602DC Cluster: Homolog of Homo sapiens "5-hydroxytryptamine 3 receptor B subunit; n=1; Takifugu rubripes|Rep: Homolog of Homo sapiens "5-hydroxytryptamine 3 receptor B subunit - Takifugu rubripes Length = 271 Score = 51.2 bits (117), Expect = 4e-05 Identities = 30/95 (31%), Positives = 49/95 (51%), Gaps = 2/95 (2%) Frame = +2 Query: 257 WIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDY-ALRARVSNNGSVSWI 430 W ++ L+WN+ + G VS LW PD+V+ + T+ +Y + A +S+NG V Sbjct: 55 WKNEFLAWNSSVFCGMELLPVSLSLLWVPDIVIREDVSDTSSNYMSPLATLSSNGWVHSS 114 Query: 431 KRLDISTPISMQLDSWPNDMQTCTFKFGSRMHNSD 535 R +++ + L +P DMQ C FGS + D Sbjct: 115 LRHVLTSTCKLDLKLFPFDMQICNLSFGSMSFSDD 149 >UniRef50_P47870-2 Cluster: Isoform Long of P47870 ; n=22; Eumetazoa|Rep: Isoform Long of P47870 - Homo sapiens (Human) Length = 512 Score = 51.2 bits (117), Expect = 4e-05 Identities = 41/169 (24%), Positives = 73/169 (43%), Gaps = 7/169 (4%) Frame = +2 Query: 62 CAIASAAECENATSLSLMIDSLLATYDRDSPPD---SKIVVNLTLHLRHAN-IRESESTV 229 CA S + N + + +D LL YD PD + V + + + + + E Sbjct: 23 CA-QSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDIASIDMVSEVNMDY 81 Query: 230 RIQADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---AR 400 + Q W DKRLS+N + +++LW PD LN + ++ R Sbjct: 82 TLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIR 141 Query: 401 VSNNGSVSWIKRLDISTPISMQLDSWPNDMQTCTFKFGSRMHNSDEMDF 547 + +G+V + R+ + M L +P D Q CT + S + +D+++F Sbjct: 142 LHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEF 190 >UniRef50_Q4RR58 Cluster: Chromosome 14 SCAF15003, whole genome shotgun sequence; n=1; Tetraodon nigroviridis|Rep: Chromosome 14 SCAF15003, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 470 Score = 51.2 bits (117), Expect = 4e-05 Identities = 35/141 (24%), Positives = 62/141 (43%), Gaps = 7/141 (4%) Frame = +2 Query: 113 MIDSLLATYDRDSPP----DSKIVVNLTLHLRHA-NIRESESTVRIQADLQMNWIDKRLS 277 + L A Y++ S P ++V L + ++ E + L+ W D +L Sbjct: 7 LFKKLFAGYNKYSRPVPNVTDVVIVKFGLSIAQLIDVDEKNQMMTTNVWLKQEWNDYKLR 66 Query: 278 WNAGEWGCSTWL-VSSERLWRPDVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDIST 451 W ++ T + V SE +W PD+VL N A A + +A + +NG + W+ ++ Sbjct: 67 WRPSDYDNVTSIRVPSELIWVPDIVLYNNADGEFAVTHMTKAHLFHNGKIRWVPPAIYNS 126 Query: 452 PISMQLDSWPNDMQTCTFKFG 514 + + +P D T KFG Sbjct: 127 SCIIDVTFFPFDQHTARCKFG 147 >UniRef50_Q9VPQ8 Cluster: CG11822-PA, isoform A (Nicotinic acetylcholine receptor beta subunit) (Nicotinic acetylcholine receptor beta 3 (Dbeta3) subunit); n=4; Sophophora|Rep: CG11822-PA, isoform A (Nicotinic acetylcholine receptor beta subunit) (Nicotinic acetylcholine receptor beta 3 (Dbeta3) subunit) - Drosophila melanogaster (Fruit fly) Length = 441 Score = 51.2 bits (117), Expect = 4e-05 Identities = 34/147 (23%), Positives = 62/147 (42%), Gaps = 5/147 (3%) Frame = +2 Query: 92 NATSLSLMIDSLLATYDRDSPP---DSKIVVNLTLHLRHANIRESESTVRIQADLQMNWI 262 N +L + L YD D P + V+L + + + +I E + L + W Sbjct: 47 NVKALDRLHAGLFTNYDSDVQPVFQGTPTNVSLEMVVTYIDIDELNGKLTTHCWLNLRWR 106 Query: 263 DKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYA-LRARVSNNGSVSWIKR 436 D+ W ++ T + + S +W P + L N G A + +S++G W+ Sbjct: 107 DEERVWQPSQYDNITQITLKSSEVWTPQITLFNG--DEGGLMAETQVTLSHDGHFRWMPP 164 Query: 437 LDISTPISMQLDSWPNDMQTCTFKFGS 517 + + + +WP+D Q+C K GS Sbjct: 165 AVYTAYCELNMLNWPHDKQSCKLKIGS 191 >UniRef50_Q14DU4 Cluster: CHRNG protein; n=3; Euarchontoglires|Rep: CHRNG protein - Homo sapiens (Human) Length = 465 Score = 51.2 bits (117), Expect = 4e-05 Identities = 33/113 (29%), Positives = 55/113 (48%), Gaps = 7/113 (6%) Frame = +2 Query: 113 MIDSLLATYDRDSPPDSKI--VVNLTLHLRHANI---RESESTVRIQADLQMNWIDKRLS 277 ++ L+ YD + P + VVN++L L N+ E E + ++M W D RL Sbjct: 29 LLADLMQNYDPNLRPAERDSDVVNVSLKLTLTNLISLNEREEALTTNVWIEMQWCDYRLR 88 Query: 278 WNAGEW-GCSTWLVSSERLWRPDVVLLNAAAT-TAGDYALRARVSNNGSVSWI 430 W+ ++ G V S +WRPD+VL N + T + + L+ + S+ WI Sbjct: 89 WDPRDYEGLWVLRVPSTMVWRPDIVLENKSQTYSTNEIDLQLSQEDGQSIEWI 141 >UniRef50_P34903 Cluster: Gamma-aminobutyric acid receptor subunit alpha-3 precursor (GABA(A) receptor subunit alpha-3); n=94; Euteleostomi|Rep: Gamma-aminobutyric acid receptor subunit alpha-3 precursor (GABA(A) receptor subunit alpha-3) - Homo sapiens (Human) Length = 492 Score = 51.2 bits (117), Expect = 4e-05 Identities = 36/158 (22%), Positives = 69/158 (43%), Gaps = 7/158 (4%) Frame = +2 Query: 89 ENATSLSLMIDSLLATYDRDSPP---DSKIVVNLTLHLRHAN-IRESESTVRIQADLQMN 256 +N T + ++D LL YD P D+ V +++ + +++ I + Sbjct: 62 DNITIFTRILDRLLDGYDNRLRPGLGDAVTEVKTDIYVTSFGPVSDTDMEYTIDVFFRQT 121 Query: 257 WIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSW 427 W D+RL ++ + + ++W PD N + A + R+ +NG++ + Sbjct: 122 WHDERLKFDGPMKILPLNNLLASKIWTPDTFFHNGKKSVAHNMTTPNKLLRLVDNGTLLY 181 Query: 428 IKRLDISTPISMQLDSWPNDMQTCTFKFGSRMHNSDEM 541 RL I M L+ +P D+ C KFGS + + E+ Sbjct: 182 TMRLTIHAECPMHLEDFPMDVHACPLKFGSYAYTTAEV 219 >UniRef50_P02708 Cluster: Acetylcholine receptor subunit alpha precursor; n=142; Coelomata|Rep: Acetylcholine receptor subunit alpha precursor - Homo sapiens (Human) Length = 482 Score = 51.2 bits (117), Expect = 4e-05 Identities = 27/92 (29%), Positives = 47/92 (51%), Gaps = 5/92 (5%) Frame = +2 Query: 257 WIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNGSV 421 W+D L WN ++G + + SE++WRPD+VL N A GD+A+ + + G + Sbjct: 105 WVDYNLKWNPDDYGGVKKIHIPSEKIWRPDLVLYNNA---DGDFAIVKFTKVLLQYTGHI 161 Query: 422 SWIKRLDISTPISMQLDSWPNDMQTCTFKFGS 517 +W + + + +P D Q C+ K G+ Sbjct: 162 TWTPPAIFKSYCEIIVTHFPFDEQNCSMKLGT 193 >UniRef50_Q9N5U8 Cluster: Acetylcholine receptor protein 21; n=2; Caenorhabditis|Rep: Acetylcholine receptor protein 21 - Caenorhabditis elegans Length = 469 Score = 50.8 bits (116), Expect = 5e-05 Identities = 32/151 (21%), Positives = 73/151 (48%), Gaps = 8/151 (5%) Frame = +2 Query: 125 LLATYDRDSPPD--SKIVVNLTLHL---RHANIRESESTVRIQADLQMNWIDKRLSWNAG 289 LL Y+ + P SK +N+T + ++ E + + ++++W+D +L W+ Sbjct: 7 LLYDYNNEVRPSVHSKEPINVTFVFSLTQIIDVDERNQILTTNSWIRLHWVDYKLVWDPR 66 Query: 290 EWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYALRARVSNN--GSVSWIKRLDISTPIS 460 + T + + S+++W+PD++L N A + V + G++ W ++ Sbjct: 67 LYQNVTRIHIPSDKIWKPDIILYNNADAQYMKSVMSTDVIVDYLGNIHWPLSAIFTSSCP 126 Query: 461 MQLDSWPNDMQTCTFKFGSRMHNSDEMDFVI 553 + + +P D QTC K+ S ++ ++D ++ Sbjct: 127 LDVKHYPFDRQTCILKYASWAYDGTKIDLLL 157 >UniRef50_Q20828 Cluster: Putative uncharacterized protein; n=2; Caenorhabditis|Rep: Putative uncharacterized protein - Caenorhabditis elegans Length = 517 Score = 50.8 bits (116), Expect = 5e-05 Identities = 42/173 (24%), Positives = 81/173 (46%), Gaps = 11/173 (6%) Frame = +2 Query: 59 TCAIASAAEC--ENATSLSLMIDSLLATYDR-DSPPDSKIVVNLTLHLRHAN-IRESEST 226 T A+A+ E E TS +I+ LL Y +P +S ++V + + ++ N + E S Sbjct: 49 TNAVAATDEDGEELCTSDKTIIEKLLNNYKSFRTPSESGVIVWIEVWVQEVNSVNEITSD 108 Query: 227 VRIQADLQMNWIDKRLSW---NAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR- 394 + + W+D L + N ++ S +++W+P+ V +N+ + + Sbjct: 109 FDMDIYVTELWMDSALRYEHLNPCKYNLSLNSEILDQIWKPNTVFINSKSANIHKSPFKN 168 Query: 395 --ARVSNNGSVSWIK-RLDISTPISMQLDSWPNDMQTCTFKFGSRMHNSDEMD 544 + NG+V W+ R+ + P SM ++P D Q+C S +N+ E+D Sbjct: 169 VFLMIYPNGTV-WVNYRVQVKGPCSMDFSAFPMDQQSCHLTLESFSYNNQEVD 220 >UniRef50_Q19351 Cluster: Ligand-gated ion channel protein 3; n=3; Caenorhabditis|Rep: Ligand-gated ion channel protein 3 - Caenorhabditis elegans Length = 355 Score = 50.8 bits (116), Expect = 5e-05 Identities = 41/166 (24%), Positives = 77/166 (46%), Gaps = 5/166 (3%) Frame = +2 Query: 59 TCAIASAAECENATSLSLMIDSLLATYDRDSPPDSKIVVNLTLHLRHA-NIRESESTVRI 235 T +A +E +S S + LL +++ SPPD ++ ++ + L H I E +++ Sbjct: 56 TVGVAEFSEQYQGSS-SRLTRHLLEKHNKCSPPDGRVDISHNIELVHIIGINELNQNMQV 114 Query: 236 QADLQMNWIDKRLSWNAGEW-GCS-TWLVSSERLWRPDVVLLNAAATTAGDYALRA--RV 403 + W D LSW E+ G TWL +W PD+++ N A+R+ +V Sbjct: 115 LVYIVQQWTDASLSWKVEEFRGIKHTWL-PEHSIWIPDIIVFNTLEHKMLLEAVRSPIKV 173 Query: 404 SNNGSVSWIKRLDISTPISMQLDSWPNDMQTCTFKFGSRMHNSDEM 541 S G V++ + + + ++P D Q +F S ++ D++ Sbjct: 174 SYTGEVTYAYPAIYTVLCQIGIATFPFDDQVYV-QFASWAYDEDKI 218 >UniRef50_P45963 Cluster: Acetylcholine receptor subunit alpha-type acr-7 precursor; n=2; Caenorhabditis|Rep: Acetylcholine receptor subunit alpha-type acr-7 precursor - Caenorhabditis elegans Length = 538 Score = 50.8 bits (116), Expect = 5e-05 Identities = 32/142 (22%), Positives = 63/142 (44%), Gaps = 8/142 (5%) Frame = +2 Query: 155 PDSKIVVNLTLHLRHANIRESE-STVRIQADLQMNWIDKRLSWNAGEWG--CSTWLVSSE 325 P + V + + ++ + +++ + + A L+ W D RL WN ++ S + Sbjct: 52 PKKALTVTMKVFIQQVLLVDAKHQMIEVNAWLKYIWTDFRLRWNPLDYENITSVRFQGED 111 Query: 326 RLWRPDVVLLNAAATTAGD-----YALRARVSNNGSVSWIKRLDISTPISMQLDSWPNDM 490 ++W+PD++L N + Y A ++G ++WI M + +P D Sbjct: 112 QIWQPDILLYNRYIEDEQESFDITYKTNAVAYSDGVINWIPPGIFKLSCKMDITLFPFDE 171 Query: 491 QTCTFKFGSRMHNSDEMDFVID 556 Q C KFGS ++ +D +D Sbjct: 172 QICFMKFGSWTYHGFALDLRLD 193 >UniRef50_Q6BET0 Cluster: Putative uncharacterized protein; n=2; Caenorhabditis|Rep: Putative uncharacterized protein - Caenorhabditis elegans Length = 536 Score = 50.4 bits (115), Expect = 6e-05 Identities = 33/163 (20%), Positives = 71/163 (43%), Gaps = 12/163 (7%) Frame = +2 Query: 95 ATSLSLMIDSLLATYDRDSPPD------SKIVVNLTLHLRHANIRESESTVRIQADLQMN 256 A +++ +++++L YD+ P +K+ ++L + + + +T + Sbjct: 59 AQNVTHLLNNVLKNYDQHFRPGFNSGKPTKVYIDLFIRTM-GPVSDLFNTYSFNCYFRQK 117 Query: 257 WIDKRLSWNAGEWG---CSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGS 418 W D RL +N G S + +++W+PD N A + R+ +G+ Sbjct: 118 WTDDRLHFNNSGIGFRQLSLSMAMLDKIWKPDTYFWNGAGSYVHGITTSNRLVRLEPDGT 177 Query: 419 VSWIKRLDISTPISMQLDSWPNDMQTCTFKFGSRMHNSDEMDF 547 + + R+ + M + +P D Q C GS ++SDE+ + Sbjct: 178 ILYSSRITVKAKCQMDMSRYPLDKQACRLVIGSYAYSSDEVQY 220 >UniRef50_A7S2G2 Cluster: Predicted protein; n=2; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 270 Score = 50.4 bits (115), Expect = 6e-05 Identities = 33/133 (24%), Positives = 63/133 (47%), Gaps = 10/133 (7%) Frame = +2 Query: 173 VNLTLHLRHANI---RESESTVRIQADLQMNWIDKRLSWNA----GEWGCSTWLVSSERL 331 VN+T+++R ++ RE ++ + W D RL++N G+ L +++ + Sbjct: 4 VNITVNMRINSVFDVREEAMDYTMRFAFRQKWRDPRLTYNISLTRGQGHPYIQLETADLI 63 Query: 332 WRPDVVLLNAAATTAGDYA---LRARVSNNGSVSWIKRLDISTPISMQLDSWPNDMQTCT 502 W PD +NA + D L R+ +GS+ +++ ++ M L +P D Q C Sbjct: 64 WYPDTFFMNARKSYIHDVTKKNLGIRLFPDGSIYMSQKITVTAECQMDLRKFPMDTQVCV 123 Query: 503 FKFGSRMHNSDEM 541 +F S H + E+ Sbjct: 124 LQFESFFHTAAEI 136 >UniRef50_A2TM50 Cluster: Nicotinic acetylcholine receptor alpha 4 subunit; n=4; Aphidinae|Rep: Nicotinic acetylcholine receptor alpha 4 subunit - Sitobion avenae (English grain aphid) Length = 532 Score = 50.4 bits (115), Expect = 6e-05 Identities = 41/154 (26%), Positives = 69/154 (44%), Gaps = 10/154 (6%) Frame = +2 Query: 113 MIDSLLATYDRDSPPDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWI-----DKRLS 277 + D LL+ Y+R P NLT+ + + +E ++ Q W+ D L Sbjct: 34 LFDDLLSNYNRLIRPVQNHSENLTVWMGLKLTQLTEMNLKSQVMTTSVWLIQKRFDCNLK 93 Query: 278 WNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNGSVSWIKRLD 442 W+ ++G L V S+ +W PD+VL N A G+Y + +A + G V W Sbjct: 94 WDPKDYGGLDKLYVPSDHIWLPDIVLFNNA---DGNYEVTLMTKAVLKYTGEVLWSPPAI 150 Query: 443 ISTPISMQLDSWPNDMQTCTFKFGSRMHNSDEMD 544 + + + +P D Q C FGS +N +++D Sbjct: 151 YKSYCEINVLYFPFDEQNCYMMFGSWTYNGNQVD 184 >UniRef50_Q95Y52 Cluster: Putative uncharacterized protein; n=2; Caenorhabditis|Rep: Putative uncharacterized protein - Caenorhabditis elegans Length = 508 Score = 50.0 bits (114), Expect = 8e-05 Identities = 36/158 (22%), Positives = 72/158 (45%), Gaps = 7/158 (4%) Frame = +2 Query: 89 ENATSLSLMIDSLLATYDRDSPPDSKIVVNLTLHLRH-ANIRESESTVRIQADLQMNWID 265 +N + S ++ ++++ Y+R P ++ V + + ++ I + S ++ + W D Sbjct: 61 KNCANDSFILGTIMSNYNRHKIPGGQVDVEVEVWVQEITTISDITSDFQLDIYIYETWYD 120 Query: 266 KRLSW---NAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYA---LRARVSNNGSVSW 427 L++ N ++ S V E+LW P+ +N+ + + NG+V Sbjct: 121 PALNYAFMNPCKYNLSLNSVLLEKLWTPNSCFINSKTADIHKSPFPNIFLMIYANGTVWT 180 Query: 428 IKRLDISTPISMQLDSWPNDMQTCTFKFGSRMHNSDEM 541 RL + P M L +P D TC+ F S +N+DE+ Sbjct: 181 NYRLKLQGPCIMDLTKFPFDNVTCSLTFESFNYNTDEV 218 >UniRef50_Q621V5 Cluster: Putative uncharacterized protein CBG02331; n=1; Caenorhabditis briggsae|Rep: Putative uncharacterized protein CBG02331 - Caenorhabditis briggsae Length = 472 Score = 50.0 bits (114), Expect = 8e-05 Identities = 42/150 (28%), Positives = 70/150 (46%), Gaps = 8/150 (5%) Frame = +2 Query: 116 IDSLLATYDRDS-PPDSKIVVNLTLHLRH-ANIRESESTVRIQADLQMNWIDKRLSWNAG 289 + LL YD+ P ++ + V++ L ++ ++I E S+ W D RL + Sbjct: 75 LSDLLQDYDKTMVPSNNSVQVSVELTVQDISSISEISSSFIADVWFSQVWEDPRLEYRNI 134 Query: 290 EWGCSTWLVS--SERLWRPDVVLLNAAATTAGDYA---LRARVSNNGSVSWIK-RLDIST 451 + L S SERLW P+V +N+ +T + + NG+V W+ R+ +S Sbjct: 135 SCKTNLSLDSYVSERLWTPNVCFVNSKSTQVHKSPASNILLIIYPNGTV-WLNYRVQVSA 193 Query: 452 PISMQLDSWPNDMQTCTFKFGSRMHNSDEM 541 P S +L +P D Q C F S +N E+ Sbjct: 194 PCSFELSRFPIDAQECHLVFESYSYNIAEV 223 >UniRef50_A7RR86 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 479 Score = 50.0 bits (114), Expect = 8e-05 Identities = 27/107 (25%), Positives = 53/107 (49%), Gaps = 5/107 (4%) Frame = +2 Query: 257 WIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAA-ATTAGD---YALRARVSNNGSV 421 W + RL W+ ++G T + +S +W PD+VL N + T G+ + + + N G++ Sbjct: 89 WSNTRLRWDPSKYGGQTSVNLSPHLIWLPDIVLYNNINSNTIGEMFKFDTKVVLHNTGAI 148 Query: 422 SWIKRLDISTPISMQLDSWPNDMQTCTFKFGSRMHNSDEMDFVIDKR 562 W + + + + +P D Q C+ FGS + S+ + I ++ Sbjct: 149 EWYAPTLVKSICKIDITYFPFDKQNCSLVFGSWTYTSEFLSLDIKQK 195 >UniRef50_A7RLM5 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 317 Score = 50.0 bits (114), Expect = 8e-05 Identities = 29/118 (24%), Positives = 52/118 (44%), Gaps = 5/118 (4%) Frame = +2 Query: 206 IRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAA----T 370 + E L+M W D L WN ++G T + + + +W P V++ N A + Sbjct: 45 VEEKNMVFTTNVRLRMGWKDAFLQWNPADYGGVTQINLEASDIWTPPVIIYNQAGDLGES 104 Query: 371 TAGDYALRARVSNNGSVSWIKRLDISTPISMQLDSWPNDMQTCTFKFGSRMHNSDEMD 544 R V ++G+V W+ I + + + +P D Q C FGS ++ ++D Sbjct: 105 ITSSNTPRPVVRSDGTVLWMVPTVIKSSCVIDVKYFPFDQQLCKIIFGSWHYDVSKLD 162 >UniRef50_UPI0000F1DA85 Cluster: PREDICTED: similar to MGC52789 protein; n=1; Danio rerio|Rep: PREDICTED: similar to MGC52789 protein - Danio rerio Length = 433 Score = 49.6 bits (113), Expect = 1e-04 Identities = 28/114 (24%), Positives = 51/114 (44%), Gaps = 2/114 (1%) Frame = +2 Query: 206 IRESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGD 382 + E ++ Q L W + +W ++ G S V + +W PD+V+ + T Sbjct: 77 VNEKAQSISTQVLLAHGWGNDFTTWKPDDFCGMSACSVKKDMVWTPDIVIAESIKTEIAT 136 Query: 383 YALR-ARVSNNGSVSWIKRLDISTPISMQLDSWPNDMQTCTFKFGSRMHNSDEM 541 R+ + G V L +++ M L +P D Q+CT S +H+SD++ Sbjct: 137 MENAFVRLESRGIVFASNTLAVTSACKMDLHLFPFDTQSCTLTIMSSVHSSDQL 190 >UniRef50_UPI0000E47329 Cluster: PREDICTED: similar to novel cholinergic receptor, nicotinic, alpha polypeptide protein; n=1; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to novel cholinergic receptor, nicotinic, alpha polypeptide protein - Strongylocentrotus purpuratus Length = 802 Score = 49.6 bits (113), Expect = 1e-04 Identities = 32/102 (31%), Positives = 47/102 (46%), Gaps = 2/102 (1%) Frame = +2 Query: 245 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAG-DYALRARVSNNGS 418 ++ W D RL W E+G T + V +E LW PD++L N A A A + G Sbjct: 449 VKQQWRDYRLQWEPEEYGGITKIKVPNECLWIPDILLYNNADGAFDIQSASWAGIDYTGL 508 Query: 419 VSWIKRLDISTPISMQLDSWPNDMQTCTFKFGSRMHNSDEMD 544 V+W + + + +P D Q C KFGS ++ MD Sbjct: 509 VTWWPPAVYKSSCQINVAYYPFDEQHCLLKFGSWTYDGVVMD 550 >UniRef50_UPI0000586C99 Cluster: PREDICTED: similar to nicotinic acetylcholine receptor subunit type A; n=1; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to nicotinic acetylcholine receptor subunit type A - Strongylocentrotus purpuratus Length = 357 Score = 49.6 bits (113), Expect = 1e-04 Identities = 29/103 (28%), Positives = 48/103 (46%), Gaps = 5/103 (4%) Frame = +2 Query: 257 WIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYALRAR----VSNNGSV 421 W D+ L W + T L + + ++W PD VL N + D + V ++GSV Sbjct: 130 WRDEYLMWEPRAYNNLTVLRIPASKIWLPDTVLYNTRQSN-NDQLMTVETLTIVKSDGSV 188 Query: 422 SWIKRLDISTPISMQLDSWPNDMQTCTFKFGSRMHNSDEMDFV 550 W L + + S+ + +P D Q C K GS H+ +D++ Sbjct: 189 DWSAPLTMISECSINVYYYPFDQQECALKMGSWQHDRKFIDYL 231 >UniRef50_UPI000069FF34 Cluster: UPI000069FF34 related cluster; n=1; Xenopus tropicalis|Rep: UPI000069FF34 UniRef100 entry - Xenopus tropicalis Length = 356 Score = 49.6 bits (113), Expect = 1e-04 Identities = 27/91 (29%), Positives = 44/91 (48%), Gaps = 1/91 (1%) Frame = +2 Query: 245 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 421 L W ++ LSW++ E+ G S + +W PD+ + + D L + NNG+V Sbjct: 3 LLQTWENQLLSWDSEEFCGISRVSIPESTIWIPDIYISETIEDNSLD-VLYVHLYNNGTV 61 Query: 422 SWIKRLDISTPISMQLDSWPNDMQTCTFKFG 514 K L++ T ++ L +P D Q C FG Sbjct: 62 QRTKTLNVMTTCTLDLYKFPFDEQKCNLTFG 92 >UniRef50_Q22224 Cluster: Putative uncharacterized protein acr-14; n=2; Caenorhabditis|Rep: Putative uncharacterized protein acr-14 - Caenorhabditis elegans Length = 500 Score = 49.6 bits (113), Expect = 1e-04 Identities = 37/130 (28%), Positives = 62/130 (47%), Gaps = 9/130 (6%) Frame = +2 Query: 203 NIRESESTVRIQADLQMNWIDKRLSWNAGEWG------CSTWLVSSERLWRPDVVLLNAA 364 ++ E + I A + +W D +L+W+ +G S +S +LWRPDV+L N+ Sbjct: 59 DVDEKNQVMSILAYMDYHWNDYKLTWDPKLFGGIRDVRFSGDDDASFKLWRPDVLLFNSV 118 Query: 365 ATT-AGDYALRARVSNNGSVSWIKRLDISTPISMQLDSWPNDMQTCTFKFGSRMHNSD-- 535 + + Y+ R VS+NG V + + +P D QTC K GS +N Sbjct: 119 SESFDSTYSSRFIVSSNGDVQQNPPGIFRFVCQIDVTYYPFDKQTCFLKLGSWTYNGQYI 178 Query: 536 EMDFVIDKRI 565 +DF++ + I Sbjct: 179 NLDFLLTQII 188 >UniRef50_P41849 Cluster: Uncharacterized glycine receptor-like protein T20B12.9; n=2; Caenorhabditis|Rep: Uncharacterized glycine receptor-like protein T20B12.9 - Caenorhabditis elegans Length = 476 Score = 49.6 bits (113), Expect = 1e-04 Identities = 46/164 (28%), Positives = 78/164 (47%), Gaps = 11/164 (6%) Frame = +2 Query: 83 ECENATSLSLMIDSLLATYDRDSPPDSKIVVNLTLHLRHANIRE-SESTVRIQADLQMN- 256 E + +L +ID+LL YD P+++ VN+T+ L + SE T D+ + Sbjct: 9 EFNSRINLGKLIDTLLTDYDTHLLPEAE-GVNVTIELHVQGVSGISEITGDFSLDVMYSE 67 Query: 257 -WIDKRLSWNAGEWGCSTWL---VSS--ERLWRPDVVLLNAAATTAGDYALRAR---VSN 409 W D RLS+ C+T + VS +++W PD ++N+ +++ + Sbjct: 68 IWQDPRLSFKHLNV-CATNITLKVSDFRKKIWTPDTCIINSKSSSIHSSPSENTFVILYE 126 Query: 410 NGSVSWIKRLDISTPISMQLDSWPNDMQTCTFKFGSRMHNSDEM 541 NG V RL++ TP S+ L +P D +C S N+DE+ Sbjct: 127 NGLVWSNFRLNVKTPCSVNLKMFPFDSLSCEIVLESYSFNTDEV 170 >UniRef50_A7S9T8 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 390 Score = 48.8 bits (111), Expect = 2e-04 Identities = 29/105 (27%), Positives = 46/105 (43%), Gaps = 5/105 (4%) Frame = +2 Query: 245 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAA--ATTAGDYALRARVS--N 409 ++ W D L W+ + G T + V LW+PD+VL N Y +V + Sbjct: 13 VRQTWTDAWLKWDPAKHGGITAINVDPSFLWKPDMVLYNNVNDEDRGEQYLFNTKVIIYS 72 Query: 410 NGSVSWIKRLDISTPISMQLDSWPNDMQTCTFKFGSRMHNSDEMD 544 G + W + T + + +P D QTC FGS +N ++D Sbjct: 73 TGDIEWYSPNILKTHCKIDIQYFPFDTQTCKLTFGSWTYNGLKID 117 >UniRef50_P48169 Cluster: Gamma-aminobutyric acid receptor subunit alpha-4 precursor (GABA(A) receptor subunit alpha-4); n=26; Euteleostomi|Rep: Gamma-aminobutyric acid receptor subunit alpha-4 precursor (GABA(A) receptor subunit alpha-4) - Homo sapiens (Human) Length = 554 Score = 48.8 bits (111), Expect = 2e-04 Identities = 39/157 (24%), Positives = 67/157 (42%), Gaps = 8/157 (5%) Frame = +2 Query: 113 MIDSLLATYD-RDSP----PDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLS 277 ++DSLL YD R P P +++ ++ + + + E + + WIDKRL Sbjct: 51 ILDSLLDGYDNRLRPGFGGPVTEVKTDIYV-TSFGPVSDVEMEYTMDVFFRQTWIDKRLK 109 Query: 278 WNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRA---RVSNNGSVSWIKRLDIS 448 ++ + ++W PD N + + + R+ NG++ + RL IS Sbjct: 110 YDGPIEILRLNNMMVTKVWTPDTFFRNGKKSVSHNMTAPNKLFRIMRNGTILYTMRLTIS 169 Query: 449 TPISMQLDSWPNDMQTCTFKFGSRMHNSDEMDFVIDK 559 M+L +P D C KFGS + EM + K Sbjct: 170 AECPMRLVDFPMDGHACPLKFGSYAYPKSEMIYTWTK 206 >UniRef50_UPI0000E47720 Cluster: PREDICTED: similar to alpha-9 nicotinic acetylcholine receptor subunit precursor; n=4; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to alpha-9 nicotinic acetylcholine receptor subunit precursor - Strongylocentrotus purpuratus Length = 572 Score = 48.4 bits (110), Expect = 3e-04 Identities = 28/101 (27%), Positives = 46/101 (45%), Gaps = 2/101 (1%) Frame = +2 Query: 257 WIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYA-LRARVSNNGSVSWI 430 W D+ + W+ ++ G V +W PD+ L YA VS+NG++ W Sbjct: 193 WTDENMIWDPLDFDGVDYVTVKKNDVWLPDICLYQNVVKDFISYADTYIVVSSNGTMDWY 252 Query: 431 KRLDISTPISMQLDSWPNDMQTCTFKFGSRMHNSDEMDFVI 553 + I+T + + +P D+Q C FG N+D + F I Sbjct: 253 VPVIIATSCPIDITYFPYDVQHCNLTFGPWTLNTDRVRFQI 293 >UniRef50_Q8TA51 Cluster: Putative uncharacterized protein; n=3; Caenorhabditis|Rep: Putative uncharacterized protein - Caenorhabditis elegans Length = 428 Score = 48.4 bits (110), Expect = 3e-04 Identities = 29/104 (27%), Positives = 48/104 (46%), Gaps = 4/104 (3%) Frame = +2 Query: 227 VRIQADLQMNWIDKRLSWNAGEWGCSTW-LVSSERLWRPDVVLLN-AAATTAGDYALRAR 400 + I L+++W D+RL WN EW L S RLW PD+ + + D+ Sbjct: 101 MNINGFLKLSWKDRRLRWNPEEWKTEVLRLKSMGRLWSPDINSDKLQTGSQSTDFVNYHD 160 Query: 401 VSNNGSVSWIKRLDISTPISMQLD--SWPNDMQTCTFKFGSRMH 526 + +N + + RL+ Q+D +PND + C F S ++ Sbjct: 161 IQSNYNGNVTARLEFRMKAQCQIDYTEYPNDRKHCCFNLQSNLY 204 >UniRef50_O44452 Cluster: Putative uncharacterized protein; n=2; Caenorhabditis|Rep: Putative uncharacterized protein - Caenorhabditis elegans Length = 464 Score = 48.4 bits (110), Expect = 3e-04 Identities = 36/152 (23%), Positives = 67/152 (44%), Gaps = 8/152 (5%) Frame = +2 Query: 113 MIDSLLATYDRDSPPDSK----IVVNLTLHLRH-ANIRESESTVRIQADLQMNWIDKRLS 277 +I+++ YD+ P ++ ++V++T+ L +RE++ W D +L+ Sbjct: 44 LIETIQRRYDKRVRPFAESNRPVIVHMTIVLGILTEVRENQQVASFVISHVQKWRDPKLA 103 Query: 278 WNAGEWGCSTWLVSSERL-WRPDVVLLNAAATT--AGDYALRARVSNNGSVSWIKRLDIS 448 WN + T +V L W P + + N+ T D R+ + G V +S Sbjct: 104 WNPADHSGLTQVVMPRSLVWVPKLFIYNSMDTKDMLTDDRYDVRIQHTGHVKVNSPQFVS 163 Query: 449 TPISMQLDSWPNDMQTCTFKFGSRMHNSDEMD 544 T + +D +P D Q C S + + +EMD Sbjct: 164 TLCRINIDLFPFDTQFCAIALASPLLSVEEMD 195 >UniRef50_Q9W288 Cluster: CG6698-PA; n=4; Sophophora|Rep: CG6698-PA - Drosophila melanogaster (Fruit fly) Length = 585 Score = 48.0 bits (109), Expect = 3e-04 Identities = 30/143 (20%), Positives = 64/143 (44%), Gaps = 4/143 (2%) Frame = +2 Query: 98 TSLSLMIDSLLATYDRDSPPDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLS 277 T ++ L + S P + ++ R ++ S ++ + + M+W D RL Sbjct: 214 TKTEKLLSHLNIQAENASMPANLSSISFHFQTRSLAYEQTSSLLQTRMHMMMHWRDSRLV 273 Query: 278 WNAGEWG-CSTWLVSSERLWRPDVVLLNAAATTAGD--YALRARVSNNGSVS-WIKRLDI 445 W ++G ++ R+W+P + +LN A + G + V NGS++ + + L + Sbjct: 274 WKPEDFGSLESFEHPDLRIWKPHMNVLNGALQSMGQVLQSYELMVYANGSITLYAQNLQL 333 Query: 446 STPISMQLDSWPNDMQTCTFKFG 514 ++ +WP++ TC + G Sbjct: 334 ASWCVDSARNWPSERVTCDIELG 356 >UniRef50_UPI00003CEF8B Cluster: R03E1.3; n=1; Caenorhabditis elegans|Rep: R03E1.3 - Caenorhabditis elegans Length = 467 Score = 47.6 bits (108), Expect = 4e-04 Identities = 28/111 (25%), Positives = 47/111 (42%), Gaps = 4/111 (3%) Frame = +2 Query: 173 VNLTLHLRHAN-IRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVV 349 VN+ L + H + E E T + + WID+ + W+A + + +S+ LW+P + Sbjct: 54 VNVFLSIAHVEKVDEHEQTALVHGHIWATWIDEYMQWDAKKENVTKLTISAHSLWQPALA 113 Query: 350 LLNAAATTAGDY---ALRARVSNNGSVSWIKRLDISTPISMQLDSWPNDMQ 493 L N+A + A+ A V + G V +WP D Q Sbjct: 114 LYNSARGNSWHLYMGAMPATVYSTGKVWSTGTFSFYVTCQFDFTNWPFDQQ 164 >UniRef50_Q4RLA7 Cluster: Chromosome 21 SCAF15022, whole genome shotgun sequence; n=5; Clupeocephala|Rep: Chromosome 21 SCAF15022, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 592 Score = 47.6 bits (108), Expect = 4e-04 Identities = 28/111 (25%), Positives = 51/111 (45%), Gaps = 2/111 (1%) Frame = +2 Query: 191 LRHANIRESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAA 367 L H + E + L+M+W D L WN E G +++++W PD++L N+A Sbjct: 78 LFHFSQDEKNQILTTNIWLRMSWFDHYLQWNQSEHPGVKNLRFTTDQIWTPDILLYNSAD 137 Query: 368 TT-AGDYALRARVSNNGSVSWIKRLDISTPISMQLDSWPNDMQTCTFKFGS 517 + V+++G + + ++ + +P D+Q C KFGS Sbjct: 138 DDFDSTFKTNVLVNSSGYAEYQPPGIFMSTCNVDVRWFPFDIQRCELKFGS 188 >UniRef50_Q9GUF0 Cluster: Ligand-gated ion channel protein 10; n=3; Caenorhabditis|Rep: Ligand-gated ion channel protein 10 - Caenorhabditis elegans Length = 493 Score = 47.6 bits (108), Expect = 4e-04 Identities = 41/165 (24%), Positives = 72/165 (43%), Gaps = 10/165 (6%) Frame = +2 Query: 77 AAECENATSL----SLMIDSLLATYDRDSPP--DSKIVVNLTLHLRHA-NIRESESTVRI 235 A CEN +L S +++ + YDR P ++VN+T+ L ++E++ Sbjct: 57 ALNCENFRTLDNETSAILNDIFVGYDRRVLPFVQGPVLVNMTIVLGILIELKENQQLAAY 116 Query: 236 QADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRA--RVS 406 W D RLSW+ ++ G +V +W P + + N+ + RA R+ Sbjct: 117 VISHTQRWYDGRLSWDPSKYRGQREVIVPQTMVWIPKLFVYNSLESKDMLTENRADVRLY 176 Query: 407 NNGSVSWIKRLDISTPISMQLDSWPNDMQTCTFKFGSRMHNSDEM 541 +NG + + +Q +S+P D Q C S + N +EM Sbjct: 177 HNGRIKINIPQYVQAICRIQTESFPFDCQFCAVALASPLLNVNEM 221 >UniRef50_A4FTX5 Cluster: CHRNB4 protein; n=1; Homo sapiens|Rep: CHRNB4 protein - Homo sapiens (Human) Length = 198 Score = 47.6 bits (108), Expect = 4e-04 Identities = 30/115 (26%), Positives = 55/115 (47%), Gaps = 8/115 (6%) Frame = +2 Query: 65 AIASAAECENATSLSLMIDSLL--ATYD---RDSPPDSKIV-VNLTLHLRHA-NIRESES 223 A+ C A + ++D LL Y+ R + S+++ + L L L ++ E E Sbjct: 14 ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQ 73 Query: 224 TVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDY 385 + L+ W D RL+WN+ + G + + ++R+W PD+VL N + T + Sbjct: 74 IMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNKSLRTGSTW 128 >UniRef50_UPI000069F132 Cluster: 5-hydroxytryptamine receptor 3 subunit D; n=3; Euteleostomi|Rep: 5-hydroxytryptamine receptor 3 subunit D - Xenopus tropicalis Length = 415 Score = 47.2 bits (107), Expect = 6e-04 Identities = 29/118 (24%), Positives = 53/118 (44%), Gaps = 2/118 (1%) Frame = +2 Query: 170 VVNLTLHLRHA-NIRESESTVRIQADLQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPD 343 VVN+++ + + E + + L M W ++ W G V +E +W PD Sbjct: 11 VVNISITVYAILGVNEKDQLLTSFLWLTMVWFNEFAEWEPALCGGVQNISVPAEEMWIPD 70 Query: 344 VVLLNAAATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDSWPNDMQTCTFKFGS 517 + +L + V +NG V ++K L + + ++ + +P D+Q CT FGS Sbjct: 71 IFVLQFVDEDKSPHLPYLLVDHNGRVRFLKPLRVVSSCNLSIFRFPFDIQNCTLTFGS 128 >UniRef50_O14764 Cluster: Gamma-aminobutyric acid receptor subunit delta precursor (GABA(A) receptor subunit delta); n=27; Euteleostomi|Rep: Gamma-aminobutyric acid receptor subunit delta precursor (GABA(A) receptor subunit delta) - Homo sapiens (Human) Length = 452 Score = 47.2 bits (107), Expect = 6e-04 Identities = 38/149 (25%), Positives = 65/149 (43%), Gaps = 7/149 (4%) Frame = +2 Query: 116 IDSLLATYDRDSPPD-SKIVVNLTLHLRHANI---RESESTVRIQADLQMNWIDKRLSWN 283 +D L+A Y R+ P VN+ L L A+I E+ + L +W D RLS+N Sbjct: 44 LDGLIAGYARNFRPGIGGPPVNVALALEVASIDHISEANMEYTMTVFLHQSWRDSRLSYN 103 Query: 284 AGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTP 454 ++LW PD ++NA + D + R+ +G + + R+ + Sbjct: 104 HTNETLGLDSRFVDKLWLPDTFIVNAKSAWFHDVTVENKLIRLQPDGVILYSIRITSTVA 163 Query: 455 ISMQLDSWPNDMQTCTFKFGSRMHNSDEM 541 M L +P D Q C S ++S+++ Sbjct: 164 CDMDLAKYPMDEQECMLDLESYGYSSEDI 192 >UniRef50_Q4RN70 Cluster: Chromosome undetermined SCAF15016, whole genome shotgun sequence; n=22; Eukaryota|Rep: Chromosome undetermined SCAF15016, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 269 Score = 46.8 bits (106), Expect = 8e-04 Identities = 40/163 (24%), Positives = 71/163 (43%), Gaps = 7/163 (4%) Frame = +2 Query: 80 AECENATSLSLMIDSLLATYDRDSPP---DSKIVVNLTLHLRHAN-IRESESTVRIQADL 247 AE + L I L+ Y++ P + + V ++L + + I E L Sbjct: 17 AEVKEGEILPPTIQRLMKGYNKYLRPFFDNGPVTVGMSLDIASIDTISEINMDYTATIFL 76 Query: 248 QMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGS 418 + W D+RL + G S E LW PD ++++ + D + R+ NG+ Sbjct: 77 RQRWTDERLVFE-GNKSLSLDGRLVELLWVPDTFIVDSKKSFLHDITVENRLIRIFPNGT 135 Query: 419 VSWIKRLDISTPISMQLDSWPNDMQTCTFKFGSRMHNSDEMDF 547 V + R+ + +M L +P D QTCT + S +N +++ F Sbjct: 136 VLYALRITTTVACNMDLTKYPMDKQTCTLQLESWGYNINDVMF 178 >UniRef50_Q4W520 Cluster: Putative uncharacterized protein; n=1; Caenorhabditis elegans|Rep: Putative uncharacterized protein - Caenorhabditis elegans Length = 397 Score = 46.8 bits (106), Expect = 8e-04 Identities = 31/133 (23%), Positives = 59/133 (44%), Gaps = 12/133 (9%) Frame = +2 Query: 185 LHLRHAN-IRESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP------ 340 LH+ H + I++ + +++ W+D+RL WN + G T+ + +WR Sbjct: 62 LHVDHIHDIQDEQGVLKMALTFTFTWMDERLMWNPSNYSGIRTFSTTRHEMWRKKFWTPT 121 Query: 341 ----DVVLLNAAATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDSWPNDMQTCTFK 508 DV + + + +S++G V R+ ++ P S+PND + CTF Sbjct: 122 LMMTDVPNSRRPSDVFKPFDMDIYISSSGMVRTSARMMLTIPCRTGFGSYPNDYKNCTFT 181 Query: 509 FGSRMHNSDEMDF 547 S + +D+ F Sbjct: 182 LMSPYY-ADQFRF 193 >UniRef50_Q2WF65 Cluster: Gaba/glycine receptor family (See gbr) protein 2, isoform a; n=3; Caenorhabditis|Rep: Gaba/glycine receptor family (See gbr) protein 2, isoform a - Caenorhabditis elegans Length = 546 Score = 46.8 bits (106), Expect = 8e-04 Identities = 35/166 (21%), Positives = 68/166 (40%), Gaps = 13/166 (7%) Frame = +2 Query: 83 ECENATSLSLMIDSLL----ATYDRDSPP-----DSKIVVNLTLHLRH-ANIRESESTVR 232 E + + + +D+LL YD SPP + VV L +++ ++ R + Sbjct: 19 EASRSEPVPIYLDNLLNAGRQVYDNQSPPVQHDKEEVTVVELAMYIEGMSSFRTQTMDFQ 78 Query: 233 IQADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYA---LRARV 403 + Q W D RL+ N ++W+PDV NA + + Sbjct: 79 LDVYFQQFWRDPRLAHNETRRVLVKDKAVLHKMWKPDVYFANARIAEFHEVTQPNFLVWI 138 Query: 404 SNNGSVSWIKRLDISTPISMQLDSWPNDMQTCTFKFGSRMHNSDEM 541 +GS+ + R+ + ++ L+ WP D Q C + S + ++++ Sbjct: 139 QPDGSILYDTRISMVVVCTLNLEKWPLDSQRCHLRILSYAYTTEQL 184 >UniRef50_O00591 Cluster: Gamma-aminobutyric acid receptor subunit pi precursor (GABA(A) receptor subunit pi); n=19; Euteleostomi|Rep: Gamma-aminobutyric acid receptor subunit pi precursor (GABA(A) receptor subunit pi) - Homo sapiens (Human) Length = 440 Score = 46.8 bits (106), Expect = 8e-04 Identities = 40/164 (24%), Positives = 78/164 (47%), Gaps = 9/164 (5%) Frame = +2 Query: 83 ECENATSLSLM-IDSLLATYDRDSPPD---SKIVVNLTLHLRH-ANIRESESTVRIQADL 247 E + LSL ++L A Y++ P+ + + LTL + ++I ES L Sbjct: 29 EVGRSDKLSLPGFENLTAGYNKFLRPNFGGEPVQIALTLDIASISSISESNMDYTATIYL 88 Query: 248 QMNWIDKRLSWNAGE-WGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNG 415 + W+D+RL + + + LV E LW PD ++ + + + + R+ +NG Sbjct: 89 RQRWMDQRLVFEGNKSFTLDARLV--EFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNG 146 Query: 416 SVSWIKRLDISTPISMQLDSWPNDMQTCTFKFGSRMHNSDEMDF 547 +V + R+ + +M L +P D QTC + S ++ ++++F Sbjct: 147 TVLYALRITTTVACNMDLSKYPMDTQTCKLQLESWGYDGNDVEF 190 >UniRef50_UPI0000E20C28 Cluster: PREDICTED: gamma-aminobutyric acid A receptor, alpha 6 isoform 1; n=1; Pan troglodytes|Rep: PREDICTED: gamma-aminobutyric acid A receptor, alpha 6 isoform 1 - Pan troglodytes Length = 478 Score = 46.4 bits (105), Expect = 0.001 Identities = 37/164 (22%), Positives = 69/164 (42%), Gaps = 8/164 (4%) Frame = +2 Query: 101 SLSLMIDSLLATYDRDSPPD---SKIVVNLTLHLRHAN-IRESESTVRIQADLQMNWIDK 268 ++S ++D+LL YD P + V +++ + + E + + W D+ Sbjct: 31 NVSRILDNLLEGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTDE 90 Query: 269 RLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRA---RVSNNGSVSWIKRL 439 RL + S + ++W PD N + A + R+ NG++ + RL Sbjct: 91 RLKFGGPTEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTMRL 150 Query: 440 DISTPISMQLDSWPNDMQTCTFKFGS-RMHNSDEMDFVIDKRIY 568 I+ M+L ++P D C KFGS +H + D + +Y Sbjct: 151 TINADCPMRLVNFPMDGHACPLKFGSYNVHFEGKKDNSSNSLLY 194 >UniRef50_UPI0000EB6CC4 Cluster: glycine receptor, beta b; n=1; Danio rerio|Rep: glycine receptor, beta b - Danio rerio Length = 451 Score = 46.4 bits (105), Expect = 0.001 Identities = 40/163 (24%), Positives = 72/163 (44%), Gaps = 11/163 (6%) Frame = +2 Query: 95 ATSLSLMIDSLLATYDRDSPPDSKIV-----VNLTLHLRHANIRESESTVRIQADLQMNW 259 A S S +++ LL TYD P+ K + VN+ ++ +I+E+ R+ L+ W Sbjct: 61 ANSTSNILNKLLITYDPRIRPNFKGIPVEDRVNIFIN-SFGSIQETTMDYRVNIFLRQRW 119 Query: 260 IDKRLSWNAGEWGCSTWLVSSER---LWRPDVVLLNAAATTAGDYA---LRARVSNNGSV 421 D RL ++ + V + LW+PD+ N + D + + NG V Sbjct: 120 NDPRLRLPQ-DFKSDSLTVDPKMFKCLWKPDLFFANEKSANFHDVTQENILLFIFRNGDV 178 Query: 422 SWIKRLDISTPISMQLDSWPNDMQTCTFKFGSRMHNSDEMDFV 550 RL ++ + L +P D Q C + S + +D++ F+ Sbjct: 179 LISMRLSVTLSCPLDLTLFPMDTQRCKMQLESFGYTTDDLQFM 221 >UniRef50_UPI0000660F16 Cluster: Homolog of Homo sapiens "Splice Isoform 2 of 5-hydroxytryptamine 3 receptor precursor; n=1; Takifugu rubripes|Rep: Homolog of Homo sapiens "Splice Isoform 2 of 5-hydroxytryptamine 3 receptor precursor - Takifugu rubripes Length = 430 Score = 46.4 bits (105), Expect = 0.001 Identities = 26/99 (26%), Positives = 42/99 (42%) Frame = +2 Query: 245 LQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVS 424 L W LSW+ E G V E +W PDV + + N G V Sbjct: 7 LMQEWDIDGLSWDVQECGTEKVSVLRESIWVPDVHIAEFMEENKSQRTPFVYLYNTGGVF 66 Query: 425 WIKRLDISTPISMQLDSWPNDMQTCTFKFGSRMHNSDEM 541 + + + + + + ++P D+Q CT FGS +H + E+ Sbjct: 67 DDRPIRVVSSCKLDIYTFPFDIQNCTLTFGSYVHFASEI 105 >UniRef50_Q7NDN8 Cluster: Glr4197 protein; n=1; Gloeobacter violaceus|Rep: Glr4197 protein - Gloeobacter violaceus Length = 359 Score = 46.4 bits (105), Expect = 0.001 Identities = 30/124 (24%), Positives = 56/124 (45%), Gaps = 5/124 (4%) Frame = +2 Query: 140 DRDSPP----DSKIVVNLTLHLRHA-NIRESESTVRIQADLQMNWIDKRLSWNAGEWGCS 304 D SPP D + VN ++L ++ + T ++ A L ++W D+RL+++ G Sbjct: 45 DMVSPPPPIADEPLTVNTGIYLIECYSLDDKAETFKVNAFLSLSWKDRRLAFDPVRSGVR 104 Query: 305 TWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDSWPN 484 E +W P++ +N D + VS +G+V +++R + +P Sbjct: 105 VKTYEPEAIWIPEIRFVNVENARDAD-VVDISVSPDGTVQYLERFSARVLSPLDFRRYPF 163 Query: 485 DMQT 496 D QT Sbjct: 164 DSQT 167 >UniRef50_A7T7Z5 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 152 Score = 46.4 bits (105), Expect = 0.001 Identities = 28/101 (27%), Positives = 47/101 (46%), Gaps = 5/101 (4%) Frame = +2 Query: 227 VRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATT-AGD---YAL 391 VR+ NW D L+W+ ++G + V+ +W P ++L N AA AG Y Sbjct: 52 VRVNVWTTQNWKDPFLTWDPSDYGGIEEINVTPTMVWLPIIILYNNAANGFAGGPEKYKT 111 Query: 392 RARVSNNGSVSWIKRLDISTPISMQLDSWPNDMQTCTFKFG 514 + +++NG+V+W + + +P D Q C FG Sbjct: 112 KVVINSNGTVNWFAATQFLFSCKINIRWFPFDEQYCYMTFG 152 >UniRef50_Q9UN88 Cluster: Gamma-aminobutyric acid receptor subunit theta precursor (GABA(A) receptor subunit theta); n=18; Tetrapoda|Rep: Gamma-aminobutyric acid receptor subunit theta precursor (GABA(A) receptor subunit theta) - Homo sapiens (Human) Length = 632 Score = 46.0 bits (104), Expect = 0.001 Identities = 35/145 (24%), Positives = 60/145 (41%), Gaps = 7/145 (4%) Frame = +2 Query: 86 CENATSLSLMIDSLLATYDRDSPPD---SKIVVNLTLHLRHAN-IRESESTVRIQADLQM 253 C N + ++D +L+ YD P+ + + V +++++ I E I Sbjct: 53 CANEAVVQKILDRVLSRYDVRLRPNFGGAPVPVRISIYVTSIEQISEMNMDYTITMFFHQ 112 Query: 254 NWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSN---NGSVS 424 W D RL++ + E+LW PD LN+ D + RV +G+V Sbjct: 113 TWKDSRLAYYETTLNLTLDYRMHEKLWVPDCYFLNSKDAFVHDVTVENRVFQLHPDGTVR 172 Query: 425 WIKRLDISTPISMQLDSWPNDMQTC 499 + RL + S+ L +P D Q C Sbjct: 173 YGIRLTTTAACSLDLHKFPMDKQAC 197 >UniRef50_UPI00015B60A2 Cluster: PREDICTED: similar to nicotinic acetylcholine receptor alpha6 subunit; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to nicotinic acetylcholine receptor alpha6 subunit - Nasonia vitripennis Length = 724 Score = 45.6 bits (103), Expect = 0.002 Identities = 22/78 (28%), Positives = 40/78 (51%), Gaps = 2/78 (2%) Frame = +2 Query: 203 NIRESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAAT-TA 376 ++ E + A L++ W D L WN E+ G ++ +LW+PDV++ N+A Sbjct: 108 DVDEKNQILTTNAWLKLEWTDYNLQWNESEFGGVKDLRITPSKLWKPDVLMYNSAEEGFD 167 Query: 377 GDYALRARVSNNGSVSWI 430 G + V++NGS ++ Sbjct: 168 GTFQTNVVVTHNGSCLYV 185 >UniRef50_UPI0000F1E62D Cluster: PREDICTED: hypothetical protein; n=1; Danio rerio|Rep: PREDICTED: hypothetical protein - Danio rerio Length = 357 Score = 45.6 bits (103), Expect = 0.002 Identities = 25/91 (27%), Positives = 41/91 (45%) Frame = +2 Query: 245 LQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVS 424 L + W + LSW+ E G + ++LW PD+V+ V +NG V Sbjct: 63 LDVFWNIEGLSWDPEECGTDRISLPRKQLWMPDIVINEFMDENKAPVTYYLYVQHNGMVM 122 Query: 425 WIKRLDISTPISMQLDSWPNDMQTCTFKFGS 517 + + + M + ++P D+Q CTF F S Sbjct: 123 DDRPTHVISSCIMDIYTFPFDIQNCTFTFNS 153 >UniRef50_UPI0000E45D33 Cluster: PREDICTED: similar to nicotinic acetylcholine receptor subunit alpha 6; n=2; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to nicotinic acetylcholine receptor subunit alpha 6 - Strongylocentrotus purpuratus Length = 440 Score = 45.6 bits (103), Expect = 0.002 Identities = 25/104 (24%), Positives = 49/104 (47%), Gaps = 4/104 (3%) Frame = +2 Query: 212 ESESTVRIQADLQMNWIDKRLSWNAGE-WGCSTWLVSSERLWRPDVVL---LNAAATTAG 379 E+ V +++++++ W D+ L W+ E G + + ++WRPDVVL L+ + Sbjct: 77 ETHQMVTVRSNMRLQWTDEYLQWDPDENGGIYNITLKTNQVWRPDVVLDEDLDRDFISIP 136 Query: 380 DYALRARVSNNGSVSWIKRLDISTPISMQLDSWPNDMQTCTFKF 511 + V G++ W+ ++ M + +P D Q C F Sbjct: 137 EADTFVIVQYTGAMDWLFPAITTSACKMNIQYFPFDTQQCVLTF 180 >UniRef50_Q4BXY7 Cluster: Neurotransmitter-gated ion-channel ligand-binding; n=2; Chroococcales|Rep: Neurotransmitter-gated ion-channel ligand-binding - Crocosphaera watsonii Length = 340 Score = 45.6 bits (103), Expect = 0.002 Identities = 36/136 (26%), Positives = 62/136 (45%), Gaps = 1/136 (0%) Frame = +2 Query: 146 DSPPDSKIVVNL-TLHLRHANIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWLVSS 322 D P ++I+V + TL L A I E E TV I L + W D R S + Sbjct: 34 DDPEITQILVGIYTLDL--AKINEVEQTVYIDFYLGLQWYDSRFDSALSNTNLSPYQRKL 91 Query: 323 ERLWRPDVVLLNAAATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDSWPNDMQTCT 502 E +W+P++ ++N + +++ G V++ +R S+ L +P D QT Sbjct: 92 EEVWQPNLHIIN-QRNLDKELDEIVHINSQGIVTYRQRYYGKLATSLDLRRFPFDEQTIK 150 Query: 503 FKFGSRMHNSDEMDFV 550 + S ++ +E+ FV Sbjct: 151 IELISFSYSPEEIHFV 166 >UniRef50_Q8MM20 Cluster: Putative uncharacterized protein; n=3; Caenorhabditis|Rep: Putative uncharacterized protein - Caenorhabditis elegans Length = 428 Score = 45.6 bits (103), Expect = 0.002 Identities = 46/163 (28%), Positives = 73/163 (44%), Gaps = 11/163 (6%) Frame = +2 Query: 86 CENATSL--SLMIDSLLATYDRDSPPDSKIVVNLTLHLRHANIRESESTVRIQADLQMN- 256 C N T + L+ID L Y++ P ++ V + + ++ SE T + DL MN Sbjct: 54 CANDTEIIDHLLIDRALY-YNKHKLPSPQVDVRIEMWVQEVT-SVSELTQDFEIDLYMNE 111 Query: 257 -WIDKRLSW---NAGEWGCS-TWLVSSERLWRPDVVLLNA--AATTAGDYA-LRARVSNN 412 W D L++ N + S W V + +W P+ +N+ A + + + V N Sbjct: 112 YWTDPGLAYDILNPCQGNLSFDWAVM-QNIWTPNTCFINSKKAQLHSSPFTNVFLMVFPN 170 Query: 413 GSVSWIKRLDISTPISMQLDSWPNDMQTCTFKFGSRMHNSDEM 541 GSV R+ + P M L +P D CT F S +N DE+ Sbjct: 171 GSVWSNWRIKSTGPCVMDLTKFPMDSIECTLTFESFNYNKDEV 213 >UniRef50_Q7PTU5 Cluster: ENSANGP00000015420; n=2; Anopheles gambiae str. PEST|Rep: ENSANGP00000015420 - Anopheles gambiae str. PEST Length = 238 Score = 45.6 bits (103), Expect = 0.002 Identities = 34/133 (25%), Positives = 57/133 (42%), Gaps = 7/133 (5%) Frame = +2 Query: 173 VNLTLH--LRHANIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPD 343 +N+T + L +I E S + Q + M W D L+WNA +W T L ++++ +W P Sbjct: 60 INITTYAVLYSFDISEYRSVMSFQVNYYMRWQDSSLAWNASDWSNITTLNINNDEIWSPQ 119 Query: 344 VVLLNAAATTAGDYAL---RARVSNNGSVSWIKRLDISTPISMQLDSWPNDMQTCTFKFG 514 +++ + + NG VS IS S WP + C F Sbjct: 120 FENIDSDYEEQPSVSCLNPDCLLRVNGYVSCSPVCRISAKCSSDYSRWPFNTLVCRMWFT 179 Query: 515 SR-MHNSDEMDFV 550 +R DE++F+ Sbjct: 180 NRDKELVDEVNFL 192 >UniRef50_A7S8Q4 Cluster: Predicted protein; n=3; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 311 Score = 45.6 bits (103), Expect = 0.002 Identities = 29/121 (23%), Positives = 58/121 (47%), Gaps = 7/121 (5%) Frame = +2 Query: 203 NIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVL---LNAAAT 370 ++ + + + ++ W + L+W+ +G L VS++ +W PD++L ++ Sbjct: 34 DVNAKQQAITVYGWVRQMWNNSLLTWDPALFGGLDILHVSAKDVWVPDILLFYNVDEQDQ 93 Query: 371 TAGD---YALRARVSNNGSVSWIKRLDISTPISMQLDSWPNDMQTCTFKFGSRMHNSDEM 541 TAG Y + +NG+ W + + +++ +P D QTC KFGS H+ + Sbjct: 94 TAGGRTTYKTDVIMYSNGTNKWRSPALLKSICKIKVKFFPFDSQTCKLKFGSFSHDITTL 153 Query: 542 D 544 D Sbjct: 154 D 154 >UniRef50_UPI00015B4D8A Cluster: PREDICTED: similar to glutamate-gated chloride channel; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to glutamate-gated chloride channel - Nasonia vitripennis Length = 510 Score = 45.2 bits (102), Expect = 0.002 Identities = 32/126 (25%), Positives = 57/126 (45%), Gaps = 6/126 (4%) Frame = +2 Query: 158 DSKIVVNLTLHLRH-ANIRESESTVRIQADLQMNWIDKRLSWN--AGEWGCSTWLVSSER 328 D +V + L +R A I + + +Q + W+D+RL +N G+ T L + R Sbjct: 60 DGPAIVRVNLFVRSIATISDIKMEYSVQLTFREQWVDERLRFNDFGGKLKYLT-LTDASR 118 Query: 329 LWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDSWPNDMQTC 499 +W PD+ N + + R+ +GSV + R+ ++ M L +P D Q C Sbjct: 119 VWMPDLFFANEKEGHFHNIIMPNVYIRIFPDGSVLYSIRISLTLSCPMNLKLYPLDRQIC 178 Query: 500 TFKFGS 517 + + S Sbjct: 179 SLRMAS 184 >UniRef50_UPI000065F0EC Cluster: Homolog of Homo sapiens "5-hydroxytryptamine receptor 3 subunit C; n=2; Takifugu rubripes|Rep: Homolog of Homo sapiens "5-hydroxytryptamine receptor 3 subunit C - Takifugu rubripes Length = 411 Score = 45.2 bits (102), Expect = 0.002 Identities = 26/99 (26%), Positives = 43/99 (43%) Frame = +2 Query: 245 LQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVS 424 L + W LSW+ E G V E +W PDV + + N G V Sbjct: 51 LGVEWDIDGLSWDVQECGTEKVSVLRESIWVPDVHIAEFMEEDQSPRTPFVYLYNTGGVF 110 Query: 425 WIKRLDISTPISMQLDSWPNDMQTCTFKFGSRMHNSDEM 541 + + + + + + ++P D+Q CT FGS +H + E+ Sbjct: 111 DDRPIRVVSSCKLDIYTFPFDIQNCTLTFGSYVHFASEI 149 >UniRef50_Q4SRT2 Cluster: Chromosome undetermined SCAF14492, whole genome shotgun sequence; n=6; Euteleostomi|Rep: Chromosome undetermined SCAF14492, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 445 Score = 45.2 bits (102), Expect = 0.002 Identities = 25/100 (25%), Positives = 47/100 (47%), Gaps = 1/100 (1%) Frame = +2 Query: 257 WIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVSWIK 433 W D+ L W+ E+ G S + SE +W PDV++ V+ +G V + Sbjct: 74 WTDEFLVWDPEEFDGLSEISLPSEAVWIPDVIVTEFVDAGKAPPIPYVYVNASGWVRSYR 133 Query: 434 RLDISTPISMQLDSWPNDMQTCTFKFGSRMHNSDEMDFVI 553 + + S+++ ++P D C+ F S +H+ E+D + Sbjct: 134 PMQVVLACSLEMFAFPFDKHNCSLSFRSWLHSVKEIDLAL 173 >UniRef50_Q93323 Cluster: Putative uncharacterized protein lgc-21; n=2; Caenorhabditis|Rep: Putative uncharacterized protein lgc-21 - Caenorhabditis elegans Length = 409 Score = 45.2 bits (102), Expect = 0.002 Identities = 37/148 (25%), Positives = 61/148 (41%), Gaps = 7/148 (4%) Frame = +2 Query: 89 ENATSLS-LMIDSLLATYDRDSPPDSKIVVNLT-LHLRHANIRESESTVRIQADLQMNWI 262 E+A L+ L I +A+ + + +N L+H + E + I L+++W Sbjct: 33 ESAKKLAKLNIPHAIASIPPNYLSQQPVTINFAQFTLQHFELNEHLKDISIHGYLELSWH 92 Query: 263 DKRLSWNAGEWGCSTWLVSS-ERLWRPDVVLLNAAATTAGDYALRAR---VSNNGSVSWI 430 D RL WN W + +V S +W P + N A R +N G+VS Sbjct: 93 DDRLMWNQDTWKKNKLVVHSFHHIWVPLLGSQNPENHLKNGDAFEIRKVETTNQGNVSAK 152 Query: 431 KRLDISTPI-SMQLDSWPNDMQTCTFKF 511 + T +++PND+ C F F Sbjct: 153 VAFSLRTFCDDTDFENYPNDVYKCCFSF 180 >UniRef50_O18276 Cluster: Gamma-aminobutyric acid receptor subunit beta precursor (GABA(A) receptor subunit beta); n=3; Rhabditida|Rep: Gamma-aminobutyric acid receptor subunit beta precursor (GABA(A) receptor subunit beta) - Caenorhabditis elegans Length = 550 Score = 45.2 bits (102), Expect = 0.002 Identities = 42/158 (26%), Positives = 71/158 (44%), Gaps = 10/158 (6%) Frame = +2 Query: 98 TSLSLMIDSLLATYD-RDSPPDSKIVVNLTLHLRHAN---IRESESTVRIQADLQMNWID 265 ++ S ++ LL YD R P + LT+ + A+ I E + + L W D Sbjct: 52 SNASSLLSDLLLDYDIRLRPGFGGDALLLTMDIIIASFDSISEVDMDYTLTMYLHQYWTD 111 Query: 266 KRLSWNAGEWGCSTWLVS---SERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSW 427 +RL W + E +S S+ +W PD L N + + R R++ +G V++ Sbjct: 112 ERLRW-SNEIPIDEMTLSGEFSQNIWVPDTFLANDKHSYLHEVTERNKMLRINVDGKVAY 170 Query: 428 IKRLDISTPISMQLDSWPNDMQTCTFKFGSRMHNSDEM 541 RL + SM L ++P D Q CT + S + + E+ Sbjct: 171 GMRLTSTLSCSMNLRNFPLDSQNCTVEIESYGYTTSEV 208 >UniRef50_UPI000058727F Cluster: PREDICTED: similar to Chain B, Refined Structure Of The Nicotinic Acetylcholine Receptor At 4a Resolution.; n=2; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to Chain B, Refined Structure Of The Nicotinic Acetylcholine Receptor At 4a Resolution. - Strongylocentrotus purpuratus Length = 449 Score = 44.8 bits (101), Expect = 0.003 Identities = 33/116 (28%), Positives = 57/116 (49%), Gaps = 5/116 (4%) Frame = +2 Query: 167 IVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWLVSSERL-WRPD 343 + V+LTL ++ E + + + + + W D+RL+W +G +G T L RL W P Sbjct: 61 VTVHLTLQ-SVKDVNEKKQGMVGTSTITVVWRDERLTWMSGHYGNITVLTLPCRLVWTPS 119 Query: 344 VVLLNAAATTA----GDYALRARVSNNGSVSWIKRLDISTPISMQLDSWPNDMQTC 499 + L N+ + + ++ + N+G V+ L ST +M L +P D QTC Sbjct: 120 IRLGNSNSEDSRILKNPEDIKVFIKNDGQVTLETNLLHSTACAMNLALFPFDTQTC 175 >UniRef50_UPI00006A0062 Cluster: UPI00006A0062 related cluster; n=1; Xenopus tropicalis|Rep: UPI00006A0062 UniRef100 entry - Xenopus tropicalis Length = 457 Score = 44.8 bits (101), Expect = 0.003 Identities = 28/103 (27%), Positives = 50/103 (48%), Gaps = 2/103 (1%) Frame = +2 Query: 239 ADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALR-ARVSNN 412 A + +W + ++W++ + G +VS +WRPD+ + + ++ N Sbjct: 78 ACITQSWKNDFVNWDSNTYCGIEKVVVSDTLVWRPDLYIYEMVDDDDKSPKINYLKIYYN 137 Query: 413 GSVSWIKRLDISTPISMQLDSWPNDMQTCTFKFGSRMHNSDEM 541 G V+ K L I+ SMQ +P D Q C+ FGS ++N E+ Sbjct: 138 GIVTNSKPLRIAGSCSMQNFKFPFDEQNCSLTFGSYVYNDFEV 180 >UniRef50_Q7ZTN5 Cluster: MGC52789 protein; n=1; Xenopus laevis|Rep: MGC52789 protein - Xenopus laevis (African clawed frog) Length = 459 Score = 44.8 bits (101), Expect = 0.003 Identities = 31/124 (25%), Positives = 56/124 (45%), Gaps = 2/124 (1%) Frame = +2 Query: 161 SKIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWR 337 S I +++TL+ A + S T+ L + W ++ +SWN + + E LW+ Sbjct: 53 SHIYIDITLYTI-AKLDTSTQTLTSFVWLTLEWTNEYISWNPNNFCDMKEFNTLGESLWK 111 Query: 338 PDVVLLNAAATTAGDYALRA-RVSNNGSVSWIKRLDISTPISMQLDSWPNDMQTCTFKFG 514 PD+ + + V +G V+ K L I + + + +P D QTC+ FG Sbjct: 112 PDLYIYQITEVDDKSPVIPYFTVHYDGKVTLDKPLRILSSCDVNIYKFPFDTQTCSLTFG 171 Query: 515 SRMH 526 S ++ Sbjct: 172 SYIY 175 >UniRef50_Q4RU50 Cluster: Chromosome 1 SCAF14995, whole genome shotgun sequence; n=3; Tetraodontidae|Rep: Chromosome 1 SCAF14995, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 1044 Score = 44.8 bits (101), Expect = 0.003 Identities = 25/90 (27%), Positives = 40/90 (44%) Frame = +2 Query: 257 WIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVSWIKR 436 W + LSW+A E G + E+LW PD+ + + N G V Sbjct: 11 WDIEGLSWDAEECGTQRVSLPREKLWIPDIHITEFMDEDKSPRTPYVYIYNTGHVFDDSP 70 Query: 437 LDISTPISMQLDSWPNDMQTCTFKFGSRMH 526 L + + + + S+P D+Q C+ FGS +H Sbjct: 71 LRVVSTCKLGIYSFPFDIQNCSLTFGSYIH 100 >UniRef50_Q6U4B6 Cluster: Nicotinic acetylcholine receptor alpha 2 subunit; n=2; Nilaparvata lugens|Rep: Nicotinic acetylcholine receptor alpha 2 subunit - Nilaparvata lugens (Brown planthopper) Length = 590 Score = 44.8 bits (101), Expect = 0.003 Identities = 35/106 (33%), Positives = 48/106 (45%), Gaps = 12/106 (11%) Frame = +2 Query: 257 WIDKRLS--WNA-----GEWGCSTWL-VSSERLWRPDVVLLNAA----ATTAGDYALRAR 400 W D + S WN G G ST L V SE +W PD+VL N A A A +A Sbjct: 100 WQDHKSSGFWNPSDDEYGGVGSSTELAVPSEHIWDPDIVLYNNADGKYAVGGSMTATKAY 159 Query: 401 VSNNGSVSWIKRLDISTPISMQLDSWPNDMQTCTFKFGSRMHNSDE 538 + G V W + + ++ +P D Q C KFGS ++ D+ Sbjct: 160 LHYGGGVWWSPPAIYGSSCEIDVEYFPFDEQGCYMKFGSWTYDGDQ 205 >UniRef50_A7SRB3 Cluster: Predicted protein; n=3; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 331 Score = 44.8 bits (101), Expect = 0.003 Identities = 25/101 (24%), Positives = 49/101 (48%), Gaps = 1/101 (0%) Frame = +2 Query: 245 LQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 421 L+ W + L WN +G + + + +W PD+VL N + + + +S++G+ Sbjct: 62 LKCLWNNHLLRWNESHYGGIKSINIDPKLVWLPDIVLYNNGSMD--QFKTKVILSSDGTN 119 Query: 422 SWIKRLDISTPISMQLDSWPNDMQTCTFKFGSRMHNSDEMD 544 +W + + S+ + +P D Q CT FGS ++ +D Sbjct: 120 TWYAPSILRSRCSIDITFFPFDDQRCTLHFGSWTYDGLRVD 160 >UniRef50_A7S763 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 278 Score = 44.8 bits (101), Expect = 0.003 Identities = 37/139 (26%), Positives = 61/139 (43%), Gaps = 5/139 (3%) Frame = +2 Query: 158 DSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWLVSS--ERL 331 D IV L +I E++ R+ + W D RL+++ + L + + + Sbjct: 4 DPVIVYTDMFVLDIGDISEADMEFRVMFFYRQYWQDTRLAYDYTGYNKRLALNARMVDYM 63 Query: 332 WRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDSWPNDMQTCT 502 W PD+ +N + D + RV +G V RL ++ M+L S+P D QTC Sbjct: 64 WIPDIYFVNEKSGIKHDLTKQNEVVRVWPDGRVFHSIRLSMTASCPMKLHSYPMDKQTCK 123 Query: 503 FKFGSRMHNSDEMDFVIDK 559 F S + S E+ F +K Sbjct: 124 LSFESFSYPSTELIFKWNK 142 >UniRef50_P25123 Cluster: Gamma-aminobutyric acid receptor subunit beta precursor (GABA(A) receptor subunit beta); n=45; Pancrustacea|Rep: Gamma-aminobutyric acid receptor subunit beta precursor (GABA(A) receptor subunit beta) - Drosophila melanogaster (Fruit fly) Length = 606 Score = 44.8 bits (101), Expect = 0.003 Identities = 40/152 (26%), Positives = 70/152 (46%), Gaps = 13/152 (8%) Frame = +2 Query: 101 SLSLMIDSLLATYDRDSPPD---SKIVVNLTLH-LRHANIRESESTVRIQADLQMNWIDK 268 ++S ++DS +YD+ P+ + V +T++ L +++ E + + W D Sbjct: 58 NISAILDSFSVSYDKRVRPNYGGPPVEVGVTMYVLSISSVSEVLMDFTLDFYFRQFWTDP 117 Query: 269 RLSWNAGEWGCSTWLVSSE---RLWRPDVVLLNAA------ATTAGDYALRARVSNNGSV 421 RL++ G T V SE +W PD +N ATT+ ++ RV ++GS+ Sbjct: 118 RLAYRKRP-GVETLSVGSEFIKNIWVPDTFFVNEKQSYFHIATTSNEFI---RVHHSGSI 173 Query: 422 SWIKRLDISTPISMQLDSWPNDMQTCTFKFGS 517 + RL I+ M L +P D Q C + S Sbjct: 174 TRSIRLTITASCPMNLQYFPMDRQLCHIEIES 205 >UniRef50_UPI0000E4906A Cluster: PREDICTED: similar to nicotinic acetylcholine receptor subunit type G; n=1; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to nicotinic acetylcholine receptor subunit type G - Strongylocentrotus purpuratus Length = 705 Score = 44.4 bits (100), Expect = 0.004 Identities = 24/104 (23%), Positives = 48/104 (46%), Gaps = 2/104 (1%) Frame = +2 Query: 212 ESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDY- 385 E++ + I A ++M+W D+ ++WN ++ G + LW PD+ L + + Y Sbjct: 35 ETQQQLTIMAYMRMSWRDEFITWNPDDYDGIELLALRPSDLWLPDIALYQSCSKEFISYQ 94 Query: 386 ALRARVSNNGSVSWIKRLDISTPISMQLDSWPNDMQTCTFKFGS 517 NG+ W +++ + + +P D+Q C FG+ Sbjct: 95 ETYVLCLYNGTCDWHFPAILTSTCKVDVRYFPFDIQLCDLTFGA 138 >UniRef50_Q4SC79 Cluster: Chromosome undetermined SCAF14659, whole genome shotgun sequence; n=2; Euteleostomi|Rep: Chromosome undetermined SCAF14659, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 481 Score = 44.4 bits (100), Expect = 0.004 Identities = 34/135 (25%), Positives = 58/135 (42%), Gaps = 7/135 (5%) Frame = +2 Query: 116 IDSLLATYDRDSPPD-SKIVVNLTLHLRHANI---RESESTVRIQADLQMNWIDKRLSWN 283 +D L+ Y R+ P VN+ + + A+I E+ + L+ +W D RLS+N Sbjct: 32 LDDLMKGYARNFRPGIGGPPVNVAMAIEVASIDHISEANMEYTMTVFLRQSWHDDRLSYN 91 Query: 284 AGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTP 454 ++LW PD ++NA + D + R+ NG + + R+ + Sbjct: 92 HTNKTLGLDSRFVDKLWLPDTFIVNAKSAWFHDVTVENKLIRLQPNGVILYSSRITSTVA 151 Query: 455 ISMQLDSWPNDMQTC 499 M L +P D Q C Sbjct: 152 CDMDLTKYPMDEQEC 166 >UniRef50_UPI0000E49D12 Cluster: PREDICTED: similar to acetylcholin receptor alpha subunit 1A; n=2; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to acetylcholin receptor alpha subunit 1A - Strongylocentrotus purpuratus Length = 462 Score = 44.0 bits (99), Expect = 0.005 Identities = 24/102 (23%), Positives = 48/102 (47%), Gaps = 2/102 (1%) Frame = +2 Query: 212 ESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYA 388 E + ++++++M W D+ L W+ EW G ++ + +W+PD L A Sbjct: 85 EHSQHITLRSNMKMTWRDEYLQWDPSEWDGITSVTLRPSDIWKPDFDLEQNVERVHFIVA 144 Query: 389 LRARVSN-NGSVSWIKRLDISTPISMQLDSWPNDMQTCTFKF 511 +++ G+V WI + +T + + +P D+Q C F Sbjct: 145 DTYVIADYTGTVRWIFPVITTTACKINIVYFPYDVQQCNVTF 186 >UniRef50_Q6U4B7 Cluster: Nicotinic acetylcholine receptor alpha 3 subunit; n=2; Nilaparvata lugens|Rep: Nicotinic acetylcholine receptor alpha 3 subunit - Nilaparvata lugens (Brown planthopper) Length = 575 Score = 44.0 bits (99), Expect = 0.005 Identities = 39/166 (23%), Positives = 69/166 (41%), Gaps = 6/166 (3%) Frame = +2 Query: 113 MIDSLLATYDRDSPP----DSKIVVNLTLHLRHANIRESESTVRI-QADLQMNWIDKRLS 277 + D LL+ Y++ P +++V L L L ++ +++ L++ W D + Sbjct: 31 LYDDLLSNYNKLIRPVGNNSDRLLVKLGLKLSQLIDVNGKNQIKVTNVWLEVTWYDYKGH 90 Query: 278 WNAGEWGCSTWLVSSERL-WRPDVVLLNAAATTAGDYALRARVSNNGSVSWIKRLDISTP 454 WN +G L L W PD+VL N A + V W + Sbjct: 91 WNPASYGGVDDLYVPLLLHWGPDIVLYNNADGKY-EVVTYGTAGILHKVEWKPPAIYKSF 149 Query: 455 ISMQLDSWPNDMQTCTFKFGSRMHNSDEMDFVIDKRIYSMFESGSV 592 + ++ +P D Q C KFGS +N ++D ++ RI ++ V Sbjct: 150 CEIDVEYFPFDEQKCVMKFGSWTYNGAQVD-LLKHRIDQNYDDNKV 194 >UniRef50_Q22085 Cluster: Putative uncharacterized protein lgc-17; n=12; Caenorhabditis|Rep: Putative uncharacterized protein lgc-17 - Caenorhabditis elegans Length = 401 Score = 44.0 bits (99), Expect = 0.005 Identities = 29/114 (25%), Positives = 48/114 (42%), Gaps = 3/114 (2%) Frame = +2 Query: 179 LTLHLRHANIRESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLL 355 L +L+ ++E E V + +L W D RLSWN+ + T V E++W P + Sbjct: 79 LLYYLKLVEVQEPEEKVSVVLELVEQWYDPRLSWNSSLYSNIPTVFVRQEKVWSPTLSAF 138 Query: 356 NA-AATTAGDYALR-ARVSNNGSVSWIKRLDISTPISMQLDSWPNDMQTCTFKF 511 D R + + G + + +S+ M + +P D QTC F Sbjct: 139 GVNEIIDFRDQDFRIVSIDDIGYIQDYLSVRVSSNCPMDVSRFPFDSQTCQICF 192 >UniRef50_O17547 Cluster: GluClalpha2A protein; n=66; Chromadorea|Rep: GluClalpha2A protein - Caenorhabditis elegans Length = 657 Score = 44.0 bits (99), Expect = 0.005 Identities = 30/134 (22%), Positives = 60/134 (44%), Gaps = 6/134 (4%) Frame = +2 Query: 167 IVVNLTLHLRH-ANIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWLV--SSERLWR 337 +VV++ + LR + I +Q + +W+DKRLS+ +L+ + + +W Sbjct: 281 VVVSVNMLLRSISKIDNVNMEYSVQLTFRESWVDKRLSFGVKGDAQPDFLILTAGQEIWM 340 Query: 338 PDVVLLN---AAATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDSWPNDMQTCTFK 508 PD N A + RV +G++ + R+ + M L +P D+Q C Sbjct: 341 PDSFFQNENQAYKHMIDKPNVLIRVHKDGTILYSVRISLVLSCPMHLQYYPMDVQQCFID 400 Query: 509 FGSRMHNSDEMDFV 550 S + + ++++V Sbjct: 401 LASYAYTTKDIEYV 414 >UniRef50_A7SDE9 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 299 Score = 44.0 bits (99), Expect = 0.005 Identities = 36/124 (29%), Positives = 57/124 (45%), Gaps = 7/124 (5%) Frame = +2 Query: 167 IVVNLTLHLRH-ANIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWLVSSE--RLWR 337 +VV+L++++ NI E+ + + W D+RL A S L E R+WR Sbjct: 4 VVVDLSIYVSSFGNIEEANMEYKFFGYFRQFWKDERL---ANRVNHSVILKGDEISRMWR 60 Query: 338 PDVVLLNA--AATTAGDYALRARVS--NNGSVSWIKRLDISTPISMQLDSWPNDMQTCTF 505 PD NA ++ T D + + V+ NG V + + I+ + L +P D Q C Sbjct: 61 PDPFCYNARKSSLTDADADINSMVTIHPNGDVVYSRMTIITAECELNLHKFPMDEQKCHL 120 Query: 506 KFGS 517 K GS Sbjct: 121 KIGS 124 >UniRef50_P34271 Cluster: Acetylcholine receptor-like protein cup-4 precursor; n=3; Caenorhabditis|Rep: Acetylcholine receptor-like protein cup-4 precursor - Caenorhabditis elegans Length = 433 Score = 44.0 bits (99), Expect = 0.005 Identities = 27/131 (20%), Positives = 56/131 (42%), Gaps = 9/131 (6%) Frame = +2 Query: 170 VVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDV 346 +V++ H+ H +I + E T+ + + M W D+ L W+ ++ + V ++W+P + Sbjct: 74 IVDVHWHIIHVSINQREQTMTVHGHIYMRWFDEFLVWDPKDFNNIQYARVKKWQVWQPKI 133 Query: 347 VLLNAAA--TTAGDYALRARV------SNNGSVSWIKRLDISTPISMQLDSWPNDMQTCT 502 + N+A+ +A D++ A V + V I + +P D+ C Sbjct: 134 KVSNSASGLGSAFDFSTSAHVIIQMMGKDRAKVEMYPTFSIKVGCAFDFTDYPYDLNKCA 193 Query: 503 FKFGSRMHNSD 535 S +D Sbjct: 194 INLFSTSTMAD 204 >UniRef50_Q4S0E0 Cluster: Chromosome 2 SCAF14781, whole genome shotgun sequence; n=5; Euteleostomi|Rep: Chromosome 2 SCAF14781, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 525 Score = 43.6 bits (98), Expect = 0.007 Identities = 33/126 (26%), Positives = 56/126 (44%), Gaps = 5/126 (3%) Frame = +2 Query: 155 PDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWLVSS--ER 328 P + N+ ++ +I E+ R+ L+ W D RL+++ S L S + Sbjct: 113 PPVNVTCNIFIN-SFGSIAETTMDYRVNIFLRQKWNDPRLAYSKYP-DPSLDLDPSMLDS 170 Query: 329 LWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDSWPNDMQTC 499 +W+PD+ N D R+ NG+V + RL + M L ++P D+QTC Sbjct: 171 IWKPDLFFANEKGANFHDVTTDNKLLRIFKNGNVLYSIRLTLILSCPMDLKNFPMDVQTC 230 Query: 500 TFKFGS 517 T + S Sbjct: 231 TMQLES 236 >UniRef50_Q61I41 Cluster: Putative uncharacterized protein CBG10413; n=1; Caenorhabditis briggsae|Rep: Putative uncharacterized protein CBG10413 - Caenorhabditis briggsae Length = 366 Score = 43.6 bits (98), Expect = 0.007 Identities = 31/133 (23%), Positives = 58/133 (43%), Gaps = 4/133 (3%) Frame = +2 Query: 152 PPDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSER 328 PP +++ + + + L+ ++ E E D W D RL+WN E+ G S V + Sbjct: 69 PPMTELNLIMAM-LKLVDVVEVEEKATFLFDYSAEWTDHRLTWNPLEYGGISHIYVPQKS 127 Query: 329 LWRPDVVLLNAAAT---TAGDYALRARVSNNGSVSWIKRLDISTPISMQLDSWPNDMQTC 499 +W P++ + +A + D A ++ NG+V + S M + +P D C Sbjct: 128 IWLPEITIADAHEVKFFESEDAPSIAWINFNGTVGFYTSTVASVICEMDVFQFPMDQHEC 187 Query: 500 TFKFGSRMHNSDE 538 + + +DE Sbjct: 188 GVSVVANTYFADE 200 >UniRef50_A7RTF8 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 262 Score = 43.6 bits (98), Expect = 0.007 Identities = 18/73 (24%), Positives = 38/73 (52%) Frame = +2 Query: 323 ERLWRPDVVLLNAAATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDSWPNDMQTCT 502 +++W+PD + N ++T + + G V + +R+ + M L ++P D Q+C+ Sbjct: 35 KQIWKPDTYINNEKSSTVPENQFLLTIDPEGRVVYSQRMTVVASCMMYLRNYPMDTQSCS 94 Query: 503 FKFGSRMHNSDEM 541 F S N+D++ Sbjct: 95 ISFESYGMNNDDL 107 >UniRef50_A7SN20 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 114 Score = 43.2 bits (97), Expect = 0.009 Identities = 30/108 (27%), Positives = 48/108 (44%), Gaps = 8/108 (7%) Frame = +2 Query: 257 WIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVL---LNAAATTAG---DYALRARVSNNG 415 W + WNA E+ G +V S ++W PDV L +N AG Y + ++G Sbjct: 1 WHHPYMRWNASEFDGIKEVMVDSSQIWVPDVTLYNNINEQDHKAGGRSTYKTDVNIYSDG 60 Query: 416 SVSWIKRLDISTPISMQLDSWPNDMQTCTFKFGSRMHNSDEMDF-VID 556 W + + + +P D QTC +F S +S +M+ V+D Sbjct: 61 RAVWRSPAIFKSTCDVYVMYFPFDKQTCYLRFSSWRMDSSKMELRVLD 108 >UniRef50_P54244 Cluster: Acetylcholine receptor subunit alpha-type deg-3 precursor; n=2; Caenorhabditis|Rep: Acetylcholine receptor subunit alpha-type deg-3 precursor - Caenorhabditis elegans Length = 564 Score = 42.7 bits (96), Expect = 0.013 Identities = 29/150 (19%), Positives = 62/150 (41%), Gaps = 10/150 (6%) Frame = +2 Query: 146 DSPPDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWNAGEWG-CSTWLVSS 322 D K+ ++++L+ + + E +++ + W D+ L WN E+G ++ ++ Sbjct: 73 DHKKSLKVHISISLY-QIIEVDEPSQNIKLNVWMIQKWRDEYLDWNPNEYGMINSTIIPF 131 Query: 323 ERLWRPDVVLLNAAATTAGD---YALRARVSN------NGSVSWIKRLDISTPISMQLDS 475 LW PD L N+ + + Y SN +S++ + + + Sbjct: 132 HHLWIPDTYLYNSVKMSRDETERYMNIQATSNYWKGEKGAELSFLYPAIYTITCRLNIRF 191 Query: 476 WPNDMQTCTFKFGSRMHNSDEMDFVIDKRI 565 +P D Q CT S ++ +D+ D + Sbjct: 192 FPYDRQNCTLTISSWTNSKSALDYYADTEV 221 >UniRef50_O16426 Cluster: Ligand-gated ion channel protein 1; n=2; Caenorhabditis elegans|Rep: Ligand-gated ion channel protein 1 - Caenorhabditis elegans Length = 371 Score = 42.3 bits (95), Expect = 0.017 Identities = 29/120 (24%), Positives = 52/120 (43%), Gaps = 4/120 (3%) Frame = +2 Query: 152 PPDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSER 328 PP +++ + + + L+ ++ E E V D W D+RL WN E+ G S V Sbjct: 51 PPITELKLTMAM-LKLVDVVEVEEKVTFLFDYLAEWTDQRLKWNPLEYGGISHIYVPQRM 109 Query: 329 LWRPDVVLLNAAAT---TAGDYALRARVSNNGSVSWIKRLDISTPISMQLDSWPNDMQTC 499 +W P+V + +A + D A ++ NG+ + S + + +P D C Sbjct: 110 IWLPEVTIADAHEVKFFESDDAPRTAWINYNGTTGFYTSTVSSVICQLDVYKFPLDRHEC 169 >UniRef50_Q94900 Cluster: Glutamate-gated chloride channel precursor; n=21; Pancrustacea|Rep: Glutamate-gated chloride channel precursor - Drosophila melanogaster (Fruit fly) Length = 456 Score = 42.3 bits (95), Expect = 0.017 Identities = 32/137 (23%), Positives = 60/137 (43%), Gaps = 6/137 (4%) Frame = +2 Query: 158 DSKIVVNLTLHLRHA-NIRESESTVRIQADLQMNWIDKRLSWN--AGEWGCSTWLVSSER 328 D +V + L +R I + + +Q + W D+RL ++ G T L + R Sbjct: 59 DGPAIVRINLFVRSIMTISDIKMEYSVQLTFREQWTDERLKFDDIQGRLKYLT-LTEANR 117 Query: 329 LWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDSWPNDMQTC 499 +W PD+ N + + R+ NGSV + R+ ++ M L +P D Q C Sbjct: 118 VWMPDLFFSNEKEGHFHNIIMPNVYIRIFPNGSVLYSIRISLTLACPMNLKLYPLDRQIC 177 Query: 500 TFKFGSRMHNSDEMDFV 550 + + S ++++ F+ Sbjct: 178 SLRMASYGWTTNDLVFL 194 >UniRef50_UPI0000E4929C Cluster: PREDICTED: similar to nicotinic acetylcholine receptor beta 1 subunit variant 1; n=1; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to nicotinic acetylcholine receptor beta 1 subunit variant 1 - Strongylocentrotus purpuratus Length = 472 Score = 41.9 bits (94), Expect = 0.022 Identities = 29/109 (26%), Positives = 51/109 (46%), Gaps = 5/109 (4%) Frame = +2 Query: 206 IRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGD 382 + + V A +++ W D RLSWN E+ +L + E +W P V++ N+A + D Sbjct: 65 LNDRRQVVSGSAWVELMWKDPRLSWNESEYDGIQYLNLDPETIWMPRVIMQNSAMESVED 124 Query: 383 -YALR---ARVSNNGSVSWIKRLDISTPISMQLDSWPNDMQTCTFKFGS 517 +A+ A + ++G + T + ++P D QTCT S Sbjct: 125 PFAMHRSYAIIFSDGYIRVTVPARFVTFCLTNVVNFPFDNQTCTVTVSS 173 >UniRef50_A2BGE6 Cluster: Glycine receptor, alpha 4b; n=5; Danio rerio|Rep: Glycine receptor, alpha 4b - Danio rerio (Zebrafish) (Brachydanio rerio) Length = 536 Score = 41.9 bits (94), Expect = 0.022 Identities = 31/135 (22%), Positives = 57/135 (42%), Gaps = 4/135 (2%) Frame = +2 Query: 155 PDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERL 331 P + N+ ++ +I E+ R+ L+ W D RL++ S + + Sbjct: 112 PPVNVTCNIFIN-SFGSITETTMDYRLNVFLRQQWNDPRLAYKEYPDDSLDLDPSMLDSI 170 Query: 332 WRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDSWPNDMQTCT 502 W+PD+ N + R+ NG+V + RL + M L ++P D QTCT Sbjct: 171 WKPDLFFANEKGANFHEVTTDNKLLRIFQNGNVLYSIRLTLILSCPMDLKNFPMDTQTCT 230 Query: 503 FKFGSRMHNSDEMDF 547 + S + +++ F Sbjct: 231 MQLESFGYTMNDLIF 245 >UniRef50_Q9U358 Cluster: Putative uncharacterized protein acc-4; n=2; Caenorhabditis|Rep: Putative uncharacterized protein acc-4 - Caenorhabditis elegans Length = 408 Score = 41.9 bits (94), Expect = 0.022 Identities = 33/152 (21%), Positives = 68/152 (44%), Gaps = 9/152 (5%) Frame = +2 Query: 113 MIDSLLATYDR-DSPPDSKIVVNLTLHLRHAN-IRESESTVRIQADLQMNWIDKRLSWNA 286 +I +L Y++ D P +VV++ + ++ + I E S + + W D L+++ Sbjct: 55 IIAQILDGYNKLDLPGGGHVVVSIEIWVQEVSKIIEITSEFELDIYVTERWTDPSLAYSH 114 Query: 287 GEWGCSTWLVSS----ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDI 445 S V ++W P +N+ + + ++ +NGS+ R+ + Sbjct: 115 LNPCKSNMSVDGATILNKIWNPHACFVNSKLANIHESPFKNIFLQIYSNGSIWHNYRIKL 174 Query: 446 STPISMQLDSWPNDMQTCTFKFGSRMHNSDEM 541 + P S L ++P D Q C + S HN+D++ Sbjct: 175 TGPCSSTLRTFPIDQQRCMLFYESFTHNTDQV 206 >UniRef50_A7SVS1 Cluster: Predicted protein; n=5; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 318 Score = 41.9 bits (94), Expect = 0.022 Identities = 38/165 (23%), Positives = 72/165 (43%), Gaps = 8/165 (4%) Frame = +2 Query: 101 SLSLMIDSLLATYDRDSPPDSKI-VVNLTLHLRHANIRE-SESTVRIQADLQMN--WIDK 268 ++S ++D + YD+ P I V++ L + + E SE+ + D+ + W + Sbjct: 1 NISKLLDDVFKRYDKRIRPYYGIKAVDIQLDMLILSFGELSETNMEFTVDMYLGQFWKEP 60 Query: 269 RLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVS----NNGSVSWIKR 436 RL++ + V+SE+LW PD +N+ T + +GSV R Sbjct: 61 RLAFGIKREIILSG-VASEKLWVPDTFFVNSIDTKVHALLFSNKKVWINLTDGSVMLSAR 119 Query: 437 LDISTPISMQLDSWPNDMQTCTFKFGSRMHNSDEMDFVIDKRIYS 571 L + L ++P D QTC F S + ++++ ++ S Sbjct: 120 LTTRNSCKVDLRNYPMDEQTCHLPFESFSYEQKDLNYTWRSKVGS 164 >UniRef50_A7RTX5 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 386 Score = 41.9 bits (94), Expect = 0.022 Identities = 26/115 (22%), Positives = 40/115 (34%), Gaps = 5/115 (4%) Frame = +2 Query: 227 VRIQADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLN-AAATTAGDYALRAR- 400 + + A + W L W+ + S E +W PD L N AG Sbjct: 76 ITVNAWILQTWTHPVLKWSPRRRNVTKTRFSIEEVWVPDTALFNNGEKAVAGRQKFFESS 135 Query: 401 ---VSNNGSVSWIKRLDISTPISMQLDSWPNDMQTCTFKFGSRMHNSDEMDFVID 556 ++ +G W ++ + WP D CT F SR + + EM D Sbjct: 136 DVIMTYDGKAKWRTYATLTNKCKLNAKFWPMDEHVCTLTFSSRRYTASEMKIQSD 190 >UniRef50_O75311 Cluster: Glycine receptor subunit alpha-3 precursor; n=128; Euteleostomi|Rep: Glycine receptor subunit alpha-3 precursor - Homo sapiens (Human) Length = 464 Score = 41.9 bits (94), Expect = 0.022 Identities = 30/135 (22%), Positives = 59/135 (43%), Gaps = 4/135 (2%) Frame = +2 Query: 155 PDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERL 331 P + N+ ++ +I E+ R+ L+ W D RL+++ S + + Sbjct: 68 PPVNVTCNIFIN-SFGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPDDSLDLDPSMLDSI 126 Query: 332 WRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDSWPNDMQTCT 502 W+PD+ N + R+ NG+V + RL ++ M L ++P D+QTC Sbjct: 127 WKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFPMDVQTCI 186 Query: 503 FKFGSRMHNSDEMDF 547 + S + +++ F Sbjct: 187 MQLESFGYTMNDLIF 201 >UniRef50_UPI0000E47589 Cluster: PREDICTED: similar to gamma-aminobutyric acid A receptor beta 2S chain precursor - chicken; n=1; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to gamma-aminobutyric acid A receptor beta 2S chain precursor - chicken - Strongylocentrotus purpuratus Length = 418 Score = 41.5 bits (93), Expect = 0.029 Identities = 25/104 (24%), Positives = 50/104 (48%), Gaps = 3/104 (2%) Frame = +2 Query: 248 QMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGS 418 + +W D+RLS++ S + +ER+W PD N + D + R ++G+ Sbjct: 11 RQHWKDERLSYDPCLGNVSLSGILAERIWVPDTYFPNDKRSFVHDVTVTNKLLRFHHDGT 70 Query: 419 VSWIKRLDISTPISMQLDSWPNDMQTCTFKFGSRMHNSDEMDFV 550 +++ R+ M L +P D Q C+ + S + + +++FV Sbjct: 71 ITYGMRITSVASCYMDLVHYPMDEQNCSLEIESYGYTTADVNFV 114 >UniRef50_Q6U4B5 Cluster: Nicotinic acetylcholine receptor beta 1 subunit; n=5; Neoptera|Rep: Nicotinic acetylcholine receptor beta 1 subunit - Nilaparvata lugens (Brown planthopper) Length = 530 Score = 41.5 bits (93), Expect = 0.029 Identities = 29/108 (26%), Positives = 48/108 (44%), Gaps = 9/108 (8%) Frame = +2 Query: 257 WIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYALRAR------VSNNG 415 W D W+ +G + L + ++W+PD+VL N A G Y ++ + + NG Sbjct: 91 WSDSLQLWDEAHYGGVSHLRLPPGKVWKPDIVLFNNAD---GHYFVKYKSHQQDMIRPNG 147 Query: 416 SVSWIKRLDISTPISMQLDS--WPNDMQTCTFKFGSRMHNSDEMDFVI 553 + W+ S +D +P D QTC KFGS ++D + Sbjct: 148 ELIWLPPAIFHDRSSCTIDVKYFPFDEQTCVMKFGSWTFPGKQVDLAL 195 >UniRef50_Q9XTE5 Cluster: Putative uncharacterized protein lgc-31; n=3; Caenorhabditis|Rep: Putative uncharacterized protein lgc-31 - Caenorhabditis elegans Length = 503 Score = 41.1 bits (92), Expect = 0.038 Identities = 27/112 (24%), Positives = 48/112 (42%), Gaps = 4/112 (3%) Frame = +2 Query: 257 WIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVL---LNAAATTAGDYALRARVSNNGSVS 424 W D+ L WN + G +SS +W P+ L LN RV+ G V Sbjct: 12 WEDEFLKWNPSSYEGAEEIFLSSSDIWIPEFSLYYSLNFNDAVKLQSNNDVRVNYTGQVR 71 Query: 425 WIKRLDISTPISMQLDSWPNDMQTCTFKFGSRMHNSDEMDFVIDKRIYSMFE 580 + + + + +P D+Q C+ FGS H++D + + + + S+ + Sbjct: 72 YYIPFSSESLCKLDVKFFPFDVQQCSLLFGSWAHSNDSIKYSLYSQNLSLID 123 >UniRef50_Q9TVI7 Cluster: Putative uncharacterized protein; n=2; Caenorhabditis|Rep: Putative uncharacterized protein - Caenorhabditis elegans Length = 538 Score = 41.1 bits (92), Expect = 0.038 Identities = 41/149 (27%), Positives = 66/149 (44%), Gaps = 10/149 (6%) Frame = +2 Query: 113 MIDSLLATYDRDSPPDSKIV-VNLTLHL-RHANIRESESTVRIQADLQMNWIDKRLSWNA 286 ++ LL+ YDR+ P K V V++ L + R + I E +S+ + W D LS+ Sbjct: 91 ILTELLSKYDRNLVPKMKGVDVDVELLIQRVSEISEIQSSSTMHILFSQIWHDPGLSFEH 150 Query: 287 GEWG-CSTWLVSSERL----WRPDVVLLNAAATTAGDYA---LRARVSNNGSVSWIKRLD 442 E C T L S R+ W P+V ++N+ + + + NG+V R+ Sbjct: 151 EEGAHCLTNLSLSHRMVDNIWLPNVCIVNSKGSAIHKSPTPNIFLAIFPNGTVWMNYRVV 210 Query: 443 ISTPISMQLDSWPNDMQTCTFKFGSRMHN 529 + +P M +P D CT F S N Sbjct: 211 VESPCEMDFSFFPMDRVMCTTIFESYAFN 239 >UniRef50_Q9NA62 Cluster: Putative uncharacterized protein; n=1; Caenorhabditis elegans|Rep: Putative uncharacterized protein - Caenorhabditis elegans Length = 434 Score = 41.1 bits (92), Expect = 0.038 Identities = 35/150 (23%), Positives = 71/150 (47%), Gaps = 10/150 (6%) Frame = +2 Query: 125 LLATYDRDSPPDS---KIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWNAGEW 295 L+ Y R++ P+ K+ V +T+ ++I T I + W DKRL+++ + Sbjct: 63 LMTNYSRNALPEPAPVKVEVEITIQ-DISDISAITGTFTIDYWISAIWNDKRLAFSHLDP 121 Query: 296 GCSTWLVSSE---RLWRPDVVLLNAAATTAGDYA---LRARVSNNGSVSWIK-RLDISTP 454 + + +LW P+V ++N+ +T D + + NG++ W+ R+ P Sbjct: 122 CRKNLSLDHDMEPKLWSPNVCIVNSKSTKVHDSPKPNILLMIFPNGTI-WLNYRIRSEAP 180 Query: 455 ISMQLDSWPNDMQTCTFKFGSRMHNSDEMD 544 M L ++P D C+ F S +N+ +++ Sbjct: 181 CQMNLRNFPLDSIRCSLVFESYSYNAADVE 210 >UniRef50_Q2PMX5 Cluster: GABA receptor; n=1; Tetranychus urticae|Rep: GABA receptor - Tetranychus urticae (Two-spotted spider mite) Length = 585 Score = 41.1 bits (92), Expect = 0.038 Identities = 33/124 (26%), Positives = 54/124 (43%), Gaps = 7/124 (5%) Frame = +2 Query: 167 IVVNLTLH-LRHANIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWLVSSE---RLW 334 + V +T+H L +++ E + + W D RLS+ A G S LV +E ++W Sbjct: 70 VKVGVTMHILTISSVSEVQMDFTADFYFRQLWRDSRLSFKARH-GISQILVDAEVADKIW 128 Query: 335 RPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDSWPNDMQTCTF 505 PD N + + R+S++G V RL ++ M L +P D Q C Sbjct: 129 VPDTFFANEKQAYFHEATTKNTFLRISHDGQVLRSIRLTVTASCPMNLQYFPMDRQKCNI 188 Query: 506 KFGS 517 + S Sbjct: 189 EIES 192 >UniRef50_A7SDF1 Cluster: Predicted protein; n=2; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 273 Score = 41.1 bits (92), Expect = 0.038 Identities = 36/153 (23%), Positives = 69/153 (45%), Gaps = 10/153 (6%) Frame = +2 Query: 113 MIDSLLATYDRDSPP---DSKIVVNLTLHLRH-ANIRESESTVRIQADLQMNWIDKRLSW 280 +I+ L A YD+ P D ++ L++ NI+E+ ++ + W + RL Sbjct: 4 IINKLFADYDKTLRPGDGDGPTLITADLYVSSFGNIQETNMEYKVFGFFRQYWREDRL-- 61 Query: 281 NAGEWGCSTWLVSSE--RLWRPDVVLLNAAATTAG--DYALRARV--SNNGSVSWIKRLD 442 AG+ + L E +W+PD NA + D ++ + V +GSV + + + Sbjct: 62 -AGKHNKTVILTGKEIDNMWKPDPFCNNARESNLRETDESISSMVFLEPDGSVLYSRLII 120 Query: 443 ISTPISMQLDSWPNDMQTCTFKFGSRMHNSDEM 541 ++ +M L +P D Q C K S + ++ + Sbjct: 121 VTAECNMNLRFFPMDEQKCYLKLSSYSYTTENI 153 >UniRef50_A7RNN1 Cluster: Predicted protein; n=2; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 317 Score = 41.1 bits (92), Expect = 0.038 Identities = 27/115 (23%), Positives = 53/115 (46%), Gaps = 7/115 (6%) Frame = +2 Query: 257 WIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLLNAA---ATTAG---DYALRARVSNNG 415 W + L WN ++G T V+ +W PD+VL N + +G + + ++G Sbjct: 72 WENPFLVWNESDYGGVHTLHVTFNDVWVPDIVLYNNGDPDLSLSGFTEKFKTFIILHSSG 131 Query: 416 SVSWIKRLDISTPISMQLDSWPNDMQTCTFKFGSRMHNSDEMDFVIDKRIYSMFE 580 + +W+ + + + +P D QTC+ FGS +++ + + + YS E Sbjct: 132 TCTWMSPTTFKSSCKLDITKFPFDSQTCSMTFGSWTYDNRLLSMDLLDKQYSHTE 186 >UniRef50_A4TVG5 Cluster: Glycine receptor, alpha 4 subunit; n=1; Magnetospirillum gryphiswaldense|Rep: Glycine receptor, alpha 4 subunit - Magnetospirillum gryphiswaldense Length = 356 Score = 40.7 bits (91), Expect = 0.050 Identities = 38/132 (28%), Positives = 57/132 (43%), Gaps = 10/132 (7%) Frame = +2 Query: 206 IRESESTVRIQADLQMNWIDKRLSW--NAGEWGCSTWL--VSSERL---WRPDVVLLNAA 364 I E+E T D+++ W D RL++ A G + + +RL W P VV N Sbjct: 48 ITENEGTFTATVDMRLRWRDLRLAYPAEAKAAGYQEYRNDAAEKRLAEIWNPGVVFSNMV 107 Query: 365 ATTAGDYALRA-RVSNNGSVSWIKRLDISTPISMQLDSWPNDMQTCTFKFGSRMH--NSD 535 Y R R+S NG V ++R + S LD +P D Q SR+ Sbjct: 108 GEPT--YQKRGLRISPNGQVELMQRTTATFTASFPLDKFPFDRQKLNVDLVSRLEPIQRV 165 Query: 536 EMDFVIDKRIYS 571 ++DF D+ +S Sbjct: 166 QLDFRQDELEFS 177 >UniRef50_O61884 Cluster: Acetylcholine receptor protein 23; n=2; Caenorhabditis|Rep: Acetylcholine receptor protein 23 - Caenorhabditis elegans Length = 545 Score = 40.7 bits (91), Expect = 0.050 Identities = 34/138 (24%), Positives = 58/138 (42%), Gaps = 9/138 (6%) Frame = +2 Query: 161 SKIVVNLTLHLRHA-NIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERLW 334 S I V L+L L + E + + + A W+D+ L W+ E+ T +++ + +W Sbjct: 50 SPINVTLSLQLYQIIQVNEPQQYLLLNAWAVERWVDQMLGWDPSEFDNETEIMARHDDIW 109 Query: 335 RPDVVLLNA------AATTAGDYALRARVSNNGS-VSWIKRLDISTPISMQLDSWPNDMQ 493 PD L N+ A+ L N G+ V + + L +P D Q Sbjct: 110 LPDTTLYNSLEMDDSASKKLTHVKLTTLGKNQGAMVELLYPTIYKISCLLNLKYFPFDTQ 169 Query: 494 TCTFKFGSRMHNSDEMDF 547 TC FGS ++ +D+ Sbjct: 170 TCRMTFGSWSFDNSLIDY 187 >UniRef50_A7S8M2 Cluster: Predicted protein; n=2; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 303 Score = 40.7 bits (91), Expect = 0.050 Identities = 38/153 (24%), Positives = 75/153 (49%), Gaps = 14/153 (9%) Frame = +2 Query: 101 SLSLMIDSLLATYD---RDSPPDSKIVVNLTLHLRHANIRESESTVRIQADLQM----NW 259 SL ++D ++ YD R + PD+ VN+ + L ++ + S + ++ + + W Sbjct: 2 SLDELLDVMVNCYDNRVRPTYPDNG-PVNIQVDLFIQSVSKF-SVINMEYSMTLYIRQRW 59 Query: 260 IDKRLSWNAGEWGCSTWLVSSE----RLWRPDVVLLNA--AATTAGD-YALRARVSNNGS 418 +D+RL++ G+ ++ + ++W PD ++N + T +G ++ R+S NGS Sbjct: 60 LDQRLAY--GDMFPEDFITLGQEMVSQIWTPDTYIVNKKQSMTNSGHGMSMFIRISRNGS 117 Query: 419 VSWIKRLDISTPISMQLDSWPNDMQTCTFKFGS 517 V + + M L ++P D Q C FK S Sbjct: 118 VIFSAENTLVLVCQMDLRNFPMDEQQCDFKIES 150 >UniRef50_A7S2G5 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 423 Score = 40.7 bits (91), Expect = 0.050 Identities = 25/86 (29%), Positives = 41/86 (47%), Gaps = 6/86 (6%) Frame = +2 Query: 113 MIDSLLATYDRDSPP----DSKIVVNLTLHLRH-ANIRESESTVRIQADLQMNWIDKRLS 277 +++ LL YDR+ P + + V L L L ++ E + ++ W + L+ Sbjct: 15 LLEKLLTGYDRNERPVLNDNESVTVTLGLTLNQIVDVDEKNQLLTTSTWIRQIWYNPLLT 74 Query: 278 WNAGEW-GCSTWLVSSERLWRPDVVL 352 WN E+ G T VS +W PD+VL Sbjct: 75 WNVTEYGGLKTINVSPTIIWLPDIVL 100 >UniRef50_UPI0000584BCE Cluster: PREDICTED: hypothetical protein; n=1; Strongylocentrotus purpuratus|Rep: PREDICTED: hypothetical protein - Strongylocentrotus purpuratus Length = 577 Score = 40.3 bits (90), Expect = 0.067 Identities = 22/103 (21%), Positives = 52/103 (50%), Gaps = 3/103 (2%) Frame = +2 Query: 212 ESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVL---LNAAATTAGD 382 E+ + + +++ W+D+ L W+ E+ + ++ + +W P++ L ++ + D Sbjct: 62 ETNQVITLVVYVRLMWVDEYLQWDPAEYDRTIMIIPKD-IWLPELTLDENVDRDFISFPD 120 Query: 383 YALRARVSNNGSVSWIKRLDISTPISMQLDSWPNDMQTCTFKF 511 + A + +G+V+W I+T + + +P D+Q CT F Sbjct: 121 TYITA--TPDGTVNWFFPAVITTTCKVDVRFFPFDIQECTLTF 161 >UniRef50_Q60NW3 Cluster: Putative uncharacterized protein CBG22525; n=1; Caenorhabditis briggsae|Rep: Putative uncharacterized protein CBG22525 - Caenorhabditis briggsae Length = 393 Score = 40.3 bits (90), Expect = 0.067 Identities = 37/178 (20%), Positives = 77/178 (43%), Gaps = 11/178 (6%) Frame = +2 Query: 110 LMIDSLLATYDRDSPPDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWNAG 289 ++I++ + R S P + I + HLR ++ +S+ T+ + + W+D+R W+ Sbjct: 40 ILINATASMPGRGSNPITAITMLHVDHLR--DLDQSKGTMSMSLSFLVTWMDERFRWDPK 97 Query: 290 EWGCSTWLVSSER------LWRPDVVLLNAAATTAG-----DYALRARVSNNGSVSWIKR 436 ++ S V+ ++ W P++ + + ++ + + V ++G+V R Sbjct: 98 DYH-SVRSVNGDKPSWSSAFWVPNIQIADMPSSQKSPGLFMNPGVEITVESSGTVKAFVR 156 Query: 437 LDISTPISMQLDSWPNDMQTCTFKFGSRMHNSDEMDFVIDKRIYSMFESGSVGCDGSV 610 ++ P +P D Q C+F S + +DE F +S SG G V Sbjct: 157 TSMTIPCYFNFGDFPRDYQNCSFTLLSPYY-ADEFQF----NDWSTINSGKYGTPDQV 209 >UniRef50_O17402 Cluster: Putative uncharacterized protein; n=2; Caenorhabditis|Rep: Putative uncharacterized protein - Caenorhabditis elegans Length = 563 Score = 40.3 bits (90), Expect = 0.067 Identities = 25/88 (28%), Positives = 40/88 (45%), Gaps = 3/88 (3%) Frame = +2 Query: 245 LQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYA---LRARVSNNG 415 L M W D+RL+ N T + ++R+W PD+ +N+ + L V +G Sbjct: 175 LAMGWFDRRLAHNCTHPILVTSKLIADRIWYPDLYFVNSKYAYLQEVTTPNLMVIVYPDG 234 Query: 416 SVSWIKRLDISTPISMQLDSWPNDMQTC 499 + RLD++ M L +P D Q C Sbjct: 235 LIFKTMRLDVTLSCMMDLKLFPLDYQEC 262 >UniRef50_Q9VGI0 Cluster: CG14723-PA, isoform A; n=12; Endopterygota|Rep: CG14723-PA, isoform A - Drosophila melanogaster (Fruit fly) Length = 426 Score = 39.9 bits (89), Expect = 0.088 Identities = 36/164 (21%), Positives = 73/164 (44%), Gaps = 10/164 (6%) Frame = +2 Query: 89 ENATSLSLMIDSLLATYDRDSPPD-----SKIVVNLTLHLRHANIRESESTVRIQADLQM 253 E++ SL ++ TYD++ P + + ++T+ L +I E T L Sbjct: 51 ESSLSLPDILPIPSKTYDKNRAPKLLGQPTVVYFHVTV-LSLDSINEESMTYVTDIFLAQ 109 Query: 254 NWIDKRLSW--NAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRAR---VSNNGS 418 +W D RL N E + +WRPD NA T + ++ + ++ + Sbjct: 110 SWRDPRLRLPENMSEQYRILDVDWLHSIWRPDCFFKNAKKVTFHEMSIPNHYLWLYHDKT 169 Query: 419 VSWIKRLDISTPISMQLDSWPNDMQTCTFKFGSRMHNSDEMDFV 550 + ++ +L + +M+ +S+P+D Q C+ S H +++ F+ Sbjct: 170 LLYMSKLTLVLSCAMKFESYPHDTQICSMMIESLSHTVEDLVFI 213 >UniRef50_Q21005 Cluster: Putative uncharacterized protein acc-1; n=2; Caenorhabditis|Rep: Putative uncharacterized protein acc-1 - Caenorhabditis elegans Length = 466 Score = 39.5 bits (88), Expect = 0.12 Identities = 39/164 (23%), Positives = 74/164 (45%), Gaps = 9/164 (5%) Frame = +2 Query: 77 AAECENATSLSLMIDSLLA-TYDRDSPPDSKIVVNLTLHLRHANIRESESTVRIQADLQM 253 A +N + + +I++LL +Y++ P V + + ++ SE T + DL + Sbjct: 24 AQSLDNCANDTEIINALLKDSYNKHYIPSHPTHVRVDMWVQEVT-SVSELTQDFEIDLYI 82 Query: 254 N--WIDKRLSW---NAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSN 409 N W D L + N + S +RLW P+ +N+ + + + V + Sbjct: 83 NEFWEDPALVYEDMNPCKRNISFDDKVLQRLWLPNTCFINSKSAAIHESPFKNVFLMVFS 142 Query: 410 NGSVSWIKRLDISTPISMQLDSWPNDMQTCTFKFGSRMHNSDEM 541 NG++ R+ ++ P M+L +P D Q C F S +N+ E+ Sbjct: 143 NGTLWTNYRMKLTGPCDMKLKRFPFDKQKCYLTFESFNYNTGEV 186 >UniRef50_O97141 Cluster: Nicotinic acetylcholine beta subunit homolog; n=1; Haementeria ghilianii|Rep: Nicotinic acetylcholine beta subunit homolog - Haementeria ghilianii (Amazon leech) Length = 233 Score = 39.5 bits (88), Expect = 0.12 Identities = 33/145 (22%), Positives = 59/145 (40%), Gaps = 1/145 (0%) Frame = +2 Query: 86 CENATSLSLMIDSLLATYDRDSPPDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWID 265 C + + + L Y+++ P+ + L A+ + V + + +W D Sbjct: 19 CSHLQGQTKLWKKLFDHYNKELEPEDA-GLKFGLAFVRAHYEKQSHEVHVHVWERYSWTD 77 Query: 266 KRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVSWIKRLD 442 KRLSW E+ G ++ VS + LW PD L + AL +++ G + ++ + Sbjct: 78 KRLSWEPSEFDGVTSLRVSHDHLWLPDFQLYHGFEERVETKAL---LTHEGHLVYVPAVL 134 Query: 443 ISTPISMQLDSWPNDMQTCTFKFGS 517 T + N C FK GS Sbjct: 135 YKT----HCEKGANHSLHCHFKVGS 155 >UniRef50_A7SDF0 Cluster: Predicted protein; n=2; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 349 Score = 39.5 bits (88), Expect = 0.12 Identities = 30/98 (30%), Positives = 47/98 (47%), Gaps = 6/98 (6%) Frame = +2 Query: 257 WIDKRLSWNAGEWGCSTWLVSSE--RLWRPDVVLLNA--AATTAGDYALRARVS--NNGS 418 W D+RL A S L E ++WRPD NA ++ TA D + + ++ NG Sbjct: 6 WKDERL---ANRLNKSVVLKGDEITKMWRPDPFCYNARESSLTASDDDINSMMTIHPNGD 62 Query: 419 VSWIKRLDISTPISMQLDSWPNDMQTCTFKFGSRMHNS 532 V + + I+ M+L +P D Q C K GS +++ Sbjct: 63 VVYSRMTIITAECEMKLHDFPMDEQQCHLKLGSYSYST 100 >UniRef50_A7RF65 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 290 Score = 39.5 bits (88), Expect = 0.12 Identities = 36/139 (25%), Positives = 62/139 (44%), Gaps = 10/139 (7%) Frame = +2 Query: 116 IDSLLATYDRDSPPDSKI-VVNLTLHL---RHANIRESESTVRIQADLQMNWIDKRLSWN 283 +++LL YD+ P S +N+T+ L R +IRE E ++ L W D RL+ Sbjct: 9 MNNLLRNYDKRIRPYSNTDKLNITVQLAVERFGDIREKEMDFSLEVYLNQTWHDDRLNHT 68 Query: 284 AGEWGCSTWLVSSE---RLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDI 445 ++S E +W+PD ++L + T + + ++G+V RL + Sbjct: 69 LDH----PIILSGEFKGSVWQPDTIILYVRSLTVYNSLSEPSSITIYSDGTVRSTVRLAL 124 Query: 446 STPISMQLDSWPNDMQTCT 502 M L +P D Q C+ Sbjct: 125 VINCLMDLRDYPLDEQECS 143 >UniRef50_O76554 Cluster: Acetylcholine receptor subunit alpha-type des-2 precursor; n=2; Caenorhabditis|Rep: Acetylcholine receptor subunit alpha-type des-2 precursor - Caenorhabditis elegans Length = 548 Score = 39.5 bits (88), Expect = 0.12 Identities = 38/176 (21%), Positives = 75/176 (42%), Gaps = 13/176 (7%) Frame = +2 Query: 59 TCAIASAAECENATSLSLMIDSLLATYDRDSPP--DSKIVVNLTLHL---RHANIRESES 223 T A A+ T + L+ D LL YD+ + P D+ +N++ + + + E + Sbjct: 12 TTASLCIADTPVPTQIRLVHD-LLDNYDKKAKPMWDNSKPINVSFSMDLYQILELNEPQQ 70 Query: 224 TVRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGD--YALR 394 + + A + W D+ L WN ++ T L + + +W PD L N+ D L Sbjct: 71 YILLNAWIIERWFDEFLYWNPDDYENITELRLPYDSIWLPDTTLYNSLVMKDDDTRRLLN 130 Query: 395 ARVSNN-----GSVSWIKRLDISTPISMQLDSWPNDMQTCTFKFGSRMHNSDEMDF 547 ++++ + + + + L +P D+Q CT F S ++ +D+ Sbjct: 131 SKLTTDTHRRAALIELLYPTIYKFSCLLDLRFFPFDVQVCTMTFSSWTYDQKGIDY 186 Database: uniref50 Posted date: Oct 5, 2007 11:19 AM Number of letters in database: 575,637,011 Number of sequences in database: 1,657,284 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.279 0.0580 0.190 Matrix: BLOSUM62 Gap Penalties: Existence: 9, Extension: 2 Number of Hits to DB: 788,667,666 Number of Sequences: 1657284 Number of extensions: 16755594 Number of successful extensions: 51395 Number of sequences better than 10.0: 289 Number of HSP's better than 10.0 without gapping: 48241 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 51095 length of database: 575,637,011 effective HSP length: 100 effective length of database: 409,908,611 effective search space used: 83211448033 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 37 (14.9 bits) X3: 62 (25.0 bits) S1: 41 (21.7 bits)
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