BLASTX 2.2.12 [Aug-07-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= BmNP01_FL5_A14 (868 letters) Database: uniref50 1,657,284 sequences; 575,637,011 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value UniRef50_UPI0000D55EDD Cluster: PREDICTED: similar to CG11822-PA... 89 1e-16 UniRef50_Q4S3I4 Cluster: Chromosome 1 SCAF14749, whole genome sh... 82 2e-14 UniRef50_Q2XWK6 Cluster: Nicotinic acetylcholine receptor subuni... 79 1e-13 UniRef50_Q4S3I6 Cluster: Chromosome 1 SCAF14749, whole genome sh... 78 3e-13 UniRef50_A7RFJ5 Cluster: Predicted protein; n=2; Nematostella ve... 76 1e-12 UniRef50_Q27218 Cluster: Acetylcholine receptor subunit beta-typ... 75 2e-12 UniRef50_P48182 Cluster: Acetylcholine receptor subunit beta-typ... 73 7e-12 UniRef50_P30532 Cluster: Neuronal acetylcholine receptor subunit... 73 9e-12 UniRef50_Q4S864 Cluster: Chromosome 5 SCAF14709, whole genome sh... 72 2e-11 UniRef50_UPI00015A3E3C Cluster: Neuronal acetylcholine receptor ... 72 2e-11 UniRef50_Q2XWK8 Cluster: Nicotinic acetylcholine receptor subuni... 71 5e-11 UniRef50_A7S3F7 Cluster: Predicted protein; n=1; Nematostella ve... 71 5e-11 UniRef50_UPI0001560C7D Cluster: PREDICTED: similar to cholinergi... 70 7e-11 UniRef50_Q15822 Cluster: Neuronal acetylcholine receptor subunit... 70 9e-11 UniRef50_P43681 Cluster: Neuronal acetylcholine receptor subunit... 69 1e-10 UniRef50_Q60KR8 Cluster: Putative uncharacterized protein CBG239... 69 2e-10 UniRef50_Q5BW84 Cluster: SJCHGC08361 protein; n=1; Schistosoma j... 69 2e-10 UniRef50_Q2XWL1 Cluster: Nicotinic acetylcholine receptor subuni... 69 2e-10 UniRef50_Q17BK7 Cluster: Nicotinic acetylcholine receptor, beta-... 69 2e-10 UniRef50_P17787 Cluster: Neuronal acetylcholine receptor subunit... 69 2e-10 UniRef50_UPI0000E49844 Cluster: PREDICTED: similar to nicotinic ... 69 2e-10 UniRef50_UPI0000E49401 Cluster: PREDICTED: similar to alpha 10 s... 69 2e-10 UniRef50_Q7T2R4 Cluster: Nicotinic acetylcholine receptor alpha ... 69 2e-10 UniRef50_Q4RIA9 Cluster: Chromosome 8 SCAF15044, whole genome sh... 68 3e-10 UniRef50_A7RHV9 Cluster: Predicted protein; n=3; Nematostella ve... 68 4e-10 UniRef50_P91766 Cluster: Acetylcholine receptor subunit alpha-li... 68 4e-10 UniRef50_UPI0000EBE733 Cluster: PREDICTED: similar to nicotinic ... 67 5e-10 UniRef50_Q4RRI3 Cluster: Chromosome 16 SCAF15002, whole genome s... 67 5e-10 UniRef50_Q93329 Cluster: Putative uncharacterized protein lev-8;... 67 5e-10 UniRef50_A7T134 Cluster: Predicted protein; n=1; Nematostella ve... 67 5e-10 UniRef50_P04755 Cluster: Acetylcholine receptor subunit beta-lik... 67 5e-10 UniRef50_P17644 Cluster: Acetylcholine receptor subunit alpha-li... 67 5e-10 UniRef50_A7RLP3 Cluster: Predicted protein; n=3; Nematostella ve... 67 6e-10 UniRef50_UPI00015B4A35 Cluster: PREDICTED: similar to nicotinic ... 66 8e-10 UniRef50_UPI0000E47D8F Cluster: PREDICTED: similar to nicotinic ... 66 8e-10 UniRef50_O44497 Cluster: Putative uncharacterized protein; n=2; ... 66 8e-10 UniRef50_Q2XWK5 Cluster: Nicotinic acetylcholine receptor subuni... 66 1e-09 UniRef50_UPI0000E48B7E Cluster: PREDICTED: similar to neuronal n... 65 2e-09 UniRef50_Q7T2S3 Cluster: Nicotinic acetylcholine receptor alpha ... 65 2e-09 UniRef50_Q9N4M3 Cluster: Acetylcholine receptor protein 6; n=1; ... 65 2e-09 UniRef50_Q8JFN7 Cluster: Neuronal acetylcholine receptor subunit... 65 2e-09 UniRef50_UPI0000E47C59 Cluster: PREDICTED: similar to alpha-9 ni... 65 3e-09 UniRef50_Q9GP98 Cluster: Acetylcholine receptor protein 22; n=3;... 65 3e-09 UniRef50_Q66T35 Cluster: Nicotinic acetylcholine receptor subuni... 65 3e-09 UniRef50_Q66T21 Cluster: Nicotinic acetylcholine receptor subuni... 65 3e-09 UniRef50_O16926 Cluster: Acetylcholine receptor protein 15; n=2;... 65 3e-09 UniRef50_P11230 Cluster: Acetylcholine receptor subunit beta pre... 65 3e-09 UniRef50_P48180 Cluster: Acetylcholine receptor subunit alpha-ty... 65 3e-09 UniRef50_Q8WSF7 Cluster: GABA A receptor alpha subunit; n=1; Apl... 64 3e-09 UniRef50_A0EIZ7 Cluster: Nicotinic acetylcholine receptor alpha9... 64 3e-09 UniRef50_Q7Z6B2 Cluster: 5-hydroxytryptamine serotonin receptor ... 64 3e-09 UniRef50_P54245 Cluster: Uncharacterized acetylcholine receptor-... 64 3e-09 UniRef50_P07510 Cluster: Acetylcholine receptor subunit gamma pr... 64 3e-09 UniRef50_UPI00015B4DDF Cluster: PREDICTED: similar to neurotrans... 64 6e-09 UniRef50_UPI0000E49402 Cluster: PREDICTED: similar to alpha 10 s... 64 6e-09 UniRef50_Q4SXG5 Cluster: Chromosome undetermined SCAF12416, whol... 64 6e-09 UniRef50_Q0GQR6 Cluster: GABA-gated ion channel; n=2; Apis melli... 64 6e-09 UniRef50_A7UFK6 Cluster: Nicotinic acetylcholine receptor alpha ... 64 6e-09 UniRef50_A7RNI2 Cluster: Predicted protein; n=3; Nematostella ve... 64 6e-09 UniRef50_UPI00015B5C4C Cluster: PREDICTED: similar to GABA-gated... 63 8e-09 UniRef50_Q24352 Cluster: Gamma-aminobutyric acid receptor alpha-... 63 8e-09 UniRef50_Q04844 Cluster: Acetylcholine receptor subunit epsilon ... 63 8e-09 UniRef50_Q2XWK3 Cluster: Nicotinic acetylcholine receptor subuni... 63 1e-08 UniRef50_UPI00015B5C6B Cluster: PREDICTED: similar to nicotinic ... 62 1e-08 UniRef50_A7RLM4 Cluster: Predicted protein; n=2; Nematostella ve... 62 1e-08 UniRef50_A2TM48 Cluster: Nicotinic acetylcholine receptor alpha ... 62 1e-08 UniRef50_Q4S866 Cluster: Chromosome 5 SCAF14709, whole genome sh... 62 2e-08 UniRef50_Q2XWL0 Cluster: Nicotinic acetylcholine receptor subuni... 62 2e-08 UniRef50_A7S622 Cluster: Predicted protein; n=1; Nematostella ve... 62 2e-08 UniRef50_Q23022 Cluster: Acetylcholine receptor subunit alpha-ty... 62 2e-08 UniRef50_Q65XS8 Cluster: Acetylcholine receptor protein 25; n=2;... 61 3e-08 UniRef50_Q9UGM1 Cluster: Neuronal acetylcholine receptor subunit... 60 5e-08 UniRef50_Q9U298 Cluster: Neuronal acetylcholine receptor subunit... 60 5e-08 UniRef50_UPI0000E47C58 Cluster: PREDICTED: similar to nicotinic ... 60 7e-08 UniRef50_Q9GQ00 Cluster: Serotonin-gated chloride channel; n=4; ... 60 7e-08 UniRef50_O62083 Cluster: Putative uncharacterized protein acr-19... 60 7e-08 UniRef50_O46132 Cluster: Nicotinic acetylcholine receptor, alpha... 60 7e-08 UniRef50_A7SI11 Cluster: Predicted protein; n=1; Nematostella ve... 60 7e-08 UniRef50_A7RS33 Cluster: Predicted protein; n=1; Nematostella ve... 60 7e-08 UniRef50_Q29ND1 Cluster: GA17977-PA; n=3; Schizophora|Rep: GA179... 60 9e-08 UniRef50_A7SW63 Cluster: Predicted protein; n=3; Nematostella ve... 60 9e-08 UniRef50_Q7KT97 Cluster: CG32975-PB, isoform B; n=69; Eumetazoa|... 59 1e-07 UniRef50_O61519 Cluster: Ligand-gated ion channel protein 6; n=4... 59 1e-07 UniRef50_A7RK99 Cluster: Predicted protein; n=2; Nematostella ve... 59 1e-07 UniRef50_UPI0000E464AB Cluster: PREDICTED: similar to nicotinic ... 59 2e-07 UniRef50_UPI0000D55E50 Cluster: PREDICTED: similar to AcetylChol... 59 2e-07 UniRef50_Q23355 Cluster: Putative uncharacterized protein acr-8;... 59 2e-07 UniRef50_P91197 Cluster: Acetylcholine receptor protein 11; n=2;... 59 2e-07 UniRef50_A7SNK1 Cluster: Predicted protein; n=2; Nematostella ve... 59 2e-07 UniRef50_A5H038 Cluster: Nicotinic acetylcholine receptor subuni... 59 2e-07 UniRef50_P25162 Cluster: Acetylcholine receptor subunit beta-lik... 58 2e-07 UniRef50_A7S9T6 Cluster: Predicted protein; n=2; Nematostella ve... 58 3e-07 UniRef50_A7RS32 Cluster: Predicted protein; n=1; Nematostella ve... 58 3e-07 UniRef50_A6QL44 Cluster: Nicotinic acetylcholine receptor non-al... 58 3e-07 UniRef50_O18228 Cluster: Putative uncharacterized protein lgc-7;... 58 4e-07 UniRef50_A7RUG1 Cluster: Predicted protein; n=2; Nematostella ve... 58 4e-07 UniRef50_UPI0000E47621 Cluster: PREDICTED: similar to nicotinic ... 57 5e-07 UniRef50_UPI0000ECB6ED Cluster: Acetylcholine receptor subunit a... 57 5e-07 UniRef50_A7S2J7 Cluster: Predicted protein; n=1; Nematostella ve... 57 5e-07 UniRef50_A0EIZ9 Cluster: Nicotinic acetylcholine receptor beta2 ... 57 5e-07 UniRef50_UPI0000D56893 Cluster: PREDICTED: similar to CG6698-PA;... 57 7e-07 UniRef50_Q4RZC6 Cluster: Chromosome 1 SCAF14944, whole genome sh... 57 7e-07 UniRef50_UPI00015B6212 Cluster: PREDICTED: similar to nicotinic ... 56 9e-07 UniRef50_UPI0000E4930A Cluster: PREDICTED: similar to nicotinic ... 56 9e-07 UniRef50_Q17BK9 Cluster: Nicotinic acetylcholine receptor, putat... 56 9e-07 UniRef50_Q07001 Cluster: Acetylcholine receptor subunit delta pr... 56 9e-07 UniRef50_P36544 Cluster: Neuronal acetylcholine receptor subunit... 56 9e-07 UniRef50_Q10052 Cluster: Gaba/glycine receptor family (See gbr) ... 56 1e-06 UniRef50_Q60S81 Cluster: Neuronal acetylcholine receptor subunit... 56 1e-06 UniRef50_UPI000058896A Cluster: PREDICTED: similar to cholinergi... 56 2e-06 UniRef50_Q19351 Cluster: Ligand-gated ion channel protein 3; n=3... 56 2e-06 UniRef50_O17848 Cluster: Putative uncharacterized protein acr-18... 56 2e-06 UniRef50_Q7PJX0 Cluster: ENSANGP00000022703; n=1; Anopheles gamb... 55 2e-06 UniRef50_Q67X94 Cluster: Putative uncharacterized protein lgc-2;... 55 2e-06 UniRef50_Q2XWL2 Cluster: Nicotinic acetylcholine receptor subuni... 55 2e-06 UniRef50_Q2XWK9 Cluster: Nicotinic acetylcholine receptor subuni... 55 2e-06 UniRef50_A7S2N9 Cluster: Predicted protein; n=3; Nematostella ve... 55 2e-06 UniRef50_UPI0000586C99 Cluster: PREDICTED: similar to nicotinic ... 55 3e-06 UniRef50_P47870-2 Cluster: Isoform Long of P47870 ; n=22; Eumeta... 55 3e-06 UniRef50_Q9XTY8 Cluster: Putative uncharacterized protein lgc-25... 55 3e-06 UniRef50_Q9N5U8 Cluster: Acetylcholine receptor protein 21; n=2;... 55 3e-06 UniRef50_Q6TMY0 Cluster: Nicotinic acetylcholine receptor non-al... 55 3e-06 UniRef50_Q22224 Cluster: Putative uncharacterized protein acr-14... 55 3e-06 UniRef50_Q6F6K3 Cluster: Acetylcholine receptor protein 17, isof... 54 4e-06 UniRef50_A7S2P0 Cluster: Predicted protein; n=4; Nematostella ve... 54 4e-06 UniRef50_Q86YW4 Cluster: Ligand-gated ion channel subunit; n=10;... 54 4e-06 UniRef50_P18505 Cluster: Gamma-aminobutyric acid receptor subuni... 54 4e-06 UniRef50_Q6Q069 Cluster: Neuronal nicotinic acetylcholine Apisa7... 54 5e-06 UniRef50_Q4R170 Cluster: Putative uncharacterized protein; n=1; ... 54 5e-06 UniRef50_Q2XWK4 Cluster: Nicotinic acetylcholine receptor subuni... 54 5e-06 UniRef50_Q18556 Cluster: Putative uncharacterized protein acr-9;... 54 5e-06 UniRef50_P31644 Cluster: Gamma-aminobutyric acid receptor subuni... 54 5e-06 UniRef50_UPI00015A4976 Cluster: 5-hydroxytryptamine receptor 3 s... 54 6e-06 UniRef50_UPI00006A0B5C Cluster: Gamma-aminobutyric-acid receptor... 54 6e-06 UniRef50_Q21645 Cluster: Acetylcholine receptor protein 10; n=2;... 54 6e-06 UniRef50_O44452 Cluster: Putative uncharacterized protein; n=2; ... 54 6e-06 UniRef50_UPI0000F2C37E Cluster: PREDICTED: similar to CHRNG prot... 53 8e-06 UniRef50_Q6TMY3 Cluster: Nicotinic acetylcholine receptor alpha ... 53 8e-06 UniRef50_A7RFJ2 Cluster: Predicted protein; n=1; Nematostella ve... 53 8e-06 UniRef50_Q14DU4 Cluster: CHRNG protein; n=3; Euarchontoglires|Re... 53 8e-06 UniRef50_P02708 Cluster: Acetylcholine receptor subunit alpha pr... 53 8e-06 UniRef50_UPI0000E47329 Cluster: PREDICTED: similar to novel chol... 53 1e-05 UniRef50_Q4V4V5 Cluster: IP12579p; n=6; Endopterygota|Rep: IP125... 52 1e-05 UniRef50_Q2XWK7 Cluster: Nicotinic acetylcholine receptor subuni... 52 1e-05 UniRef50_Q0GQQ6 Cluster: Cys-loop ligand-gated ion channel subun... 52 1e-05 UniRef50_A7RND6 Cluster: Predicted protein; n=1; Nematostella ve... 52 2e-05 UniRef50_Q4RLA7 Cluster: Chromosome 21 SCAF15022, whole genome s... 52 3e-05 UniRef50_P46098 Cluster: 5-hydroxytryptamine receptor 3 precurso... 52 3e-05 UniRef50_UPI0000E48474 Cluster: PREDICTED: similar to nicotinic ... 51 3e-05 UniRef50_Q7ZTN5 Cluster: MGC52789 protein; n=1; Xenopus laevis|R... 51 3e-05 UniRef50_A7SLK4 Cluster: Predicted protein; n=2; Nematostella ve... 51 3e-05 UniRef50_UPI0000E473D1 Cluster: PREDICTED: similar to neuronal a... 51 4e-05 UniRef50_UPI00006602DC Cluster: Homolog of Homo sapiens "5-hydro... 51 4e-05 UniRef50_A7RR86 Cluster: Predicted protein; n=1; Nematostella ve... 51 4e-05 UniRef50_A6XBS1 Cluster: Amorphous calcium carbonate binding pro... 51 4e-05 UniRef50_Q99928 Cluster: Gamma-aminobutyric acid receptor subuni... 51 4e-05 UniRef50_P34903 Cluster: Gamma-aminobutyric acid receptor subuni... 51 4e-05 UniRef50_UPI0000E47720 Cluster: PREDICTED: similar to alpha-9 ni... 50 6e-05 UniRef50_Q9VPQ8 Cluster: CG11822-PA, isoform A (Nicotinic acetyl... 50 6e-05 UniRef50_Q9GQU9 Cluster: Nicotinic acetylcholine receptor-like s... 50 6e-05 UniRef50_Q621V5 Cluster: Putative uncharacterized protein CBG023... 50 6e-05 UniRef50_UPI0000660F16 Cluster: Homolog of Homo sapiens "Splice ... 50 8e-05 UniRef50_Q4RR58 Cluster: Chromosome 14 SCAF15003, whole genome s... 50 8e-05 UniRef50_Q6BET0 Cluster: Putative uncharacterized protein; n=2; ... 50 8e-05 UniRef50_UPI000069FF34 Cluster: UPI000069FF34 related cluster; n... 50 1e-04 UniRef50_Q95Y52 Cluster: Putative uncharacterized protein; n=2; ... 50 1e-04 UniRef50_Q9W288 Cluster: CG6698-PA; n=4; Sophophora|Rep: CG6698-... 49 1e-04 UniRef50_A7S2G2 Cluster: Predicted protein; n=2; Nematostella ve... 49 1e-04 UniRef50_A7RLM5 Cluster: Predicted protein; n=1; Nematostella ve... 49 1e-04 UniRef50_P45963 Cluster: Acetylcholine receptor subunit alpha-ty... 49 1e-04 UniRef50_UPI0000E49D12 Cluster: PREDICTED: similar to acetylchol... 49 2e-04 UniRef50_UPI000069F132 Cluster: 5-hydroxytryptamine receptor 3 s... 49 2e-04 UniRef50_UPI000065F0EC Cluster: Homolog of Homo sapiens "5-hydro... 49 2e-04 UniRef50_Q20828 Cluster: Putative uncharacterized protein; n=2; ... 49 2e-04 UniRef50_A7S9T8 Cluster: Predicted protein; n=1; Nematostella ve... 49 2e-04 UniRef50_A7S6R3 Cluster: Predicted protein; n=3; Nematostella ve... 49 2e-04 UniRef50_P41849 Cluster: Uncharacterized glycine receptor-like p... 49 2e-04 UniRef50_UPI00003CEF8B Cluster: R03E1.3; n=1; Caenorhabditis ele... 48 2e-04 UniRef50_Q9GUF0 Cluster: Ligand-gated ion channel protein 10; n=... 48 2e-04 UniRef50_Q6U4B6 Cluster: Nicotinic acetylcholine receptor alpha ... 48 2e-04 UniRef50_Q2WF65 Cluster: Gaba/glycine receptor family (See gbr) ... 48 2e-04 UniRef50_A2TM50 Cluster: Nicotinic acetylcholine receptor alpha ... 48 2e-04 UniRef50_P48169 Cluster: Gamma-aminobutyric acid receptor subuni... 48 2e-04 UniRef50_UPI0000F1E62D Cluster: PREDICTED: hypothetical protein;... 48 4e-04 UniRef50_UPI0000E20C28 Cluster: PREDICTED: gamma-aminobutyric ac... 48 4e-04 UniRef50_Q8TA51 Cluster: Putative uncharacterized protein; n=3; ... 48 4e-04 UniRef50_Q22085 Cluster: Putative uncharacterized protein lgc-17... 48 4e-04 UniRef50_O18276 Cluster: Gamma-aminobutyric acid receptor subuni... 48 4e-04 UniRef50_Q4RN70 Cluster: Chromosome undetermined SCAF15016, whol... 47 5e-04 UniRef50_O16426 Cluster: Ligand-gated ion channel protein 1; n=2... 47 5e-04 UniRef50_A7S8Q4 Cluster: Predicted protein; n=3; Nematostella ve... 47 7e-04 UniRef50_A4FTX5 Cluster: CHRNB4 protein; n=1; Homo sapiens|Rep: ... 47 7e-04 UniRef50_Q9UN88 Cluster: Gamma-aminobutyric acid receptor subuni... 47 7e-04 UniRef50_O00591 Cluster: Gamma-aminobutyric acid receptor subuni... 47 7e-04 UniRef50_O14764 Cluster: Gamma-aminobutyric acid receptor subuni... 47 7e-04 UniRef50_UPI0000F1DA85 Cluster: PREDICTED: similar to MGC52789 p... 46 0.001 UniRef50_UPI0000E45D33 Cluster: PREDICTED: similar to nicotinic ... 46 0.001 UniRef50_Q7NDN8 Cluster: Glr4197 protein; n=1; Gloeobacter viola... 46 0.001 UniRef50_Q61I41 Cluster: Putative uncharacterized protein CBG104... 46 0.001 UniRef50_O75311 Cluster: Glycine receptor subunit alpha-3 precur... 46 0.001 UniRef50_UPI00015B60A2 Cluster: PREDICTED: similar to nicotinic ... 46 0.002 UniRef50_UPI0000EB6CC4 Cluster: glycine receptor, beta b; n=1; D... 46 0.002 UniRef50_UPI00006A0062 Cluster: UPI00006A0062 related cluster; n... 46 0.002 UniRef50_Q93323 Cluster: Putative uncharacterized protein lgc-21... 46 0.002 UniRef50_Q4W520 Cluster: Putative uncharacterized protein; n=1; ... 46 0.002 UniRef50_A7T7Z5 Cluster: Predicted protein; n=1; Nematostella ve... 46 0.002 UniRef50_A7RTF8 Cluster: Predicted protein; n=1; Nematostella ve... 46 0.002 UniRef50_UPI0000E4906A Cluster: PREDICTED: similar to nicotinic ... 45 0.002 UniRef50_A7SDE9 Cluster: Predicted protein; n=1; Nematostella ve... 45 0.002 UniRef50_A7SVS1 Cluster: Predicted protein; n=5; Nematostella ve... 45 0.003 UniRef50_UPI000058727F Cluster: PREDICTED: similar to Chain B, R... 44 0.004 UniRef50_Q4S0E0 Cluster: Chromosome 2 SCAF14781, whole genome sh... 44 0.004 UniRef50_A7SRB3 Cluster: Predicted protein; n=3; Nematostella ve... 44 0.004 UniRef50_Q4SRT3 Cluster: Chromosome undetermined SCAF14492, whol... 44 0.005 UniRef50_Q4SRT2 Cluster: Chromosome undetermined SCAF14492, whol... 44 0.005 UniRef50_Q4SC79 Cluster: Chromosome undetermined SCAF14659, whol... 44 0.005 UniRef50_Q9XTE5 Cluster: Putative uncharacterized protein lgc-31... 44 0.005 UniRef50_Q8MM20 Cluster: Putative uncharacterized protein; n=3; ... 44 0.005 UniRef50_P25123 Cluster: Gamma-aminobutyric acid receptor subuni... 44 0.005 UniRef50_Q4RU50 Cluster: Chromosome 1 SCAF14995, whole genome sh... 44 0.007 UniRef50_A2BGE6 Cluster: Glycine receptor, alpha 4b; n=5; Danio ... 44 0.007 UniRef50_Q4BXY7 Cluster: Neurotransmitter-gated ion-channel liga... 44 0.007 UniRef50_UPI00015B4D8A Cluster: PREDICTED: similar to glutamate-... 43 0.009 UniRef50_UPI0000E4929C Cluster: PREDICTED: similar to nicotinic ... 43 0.009 UniRef50_Q7PTU5 Cluster: ENSANGP00000015420; n=2; Anopheles gamb... 43 0.009 UniRef50_Q6U4B7 Cluster: Nicotinic acetylcholine receptor alpha ... 43 0.009 UniRef50_A7SN20 Cluster: Predicted protein; n=1; Nematostella ve... 43 0.009 UniRef50_P34271 Cluster: Acetylcholine receptor-like protein cup... 43 0.009 UniRef50_UPI000065DFE4 Cluster: 5-hydroxytryptamine 3 receptor p... 43 0.012 UniRef50_A4TVG5 Cluster: Glycine receptor, alpha 4 subunit; n=1;... 43 0.012 UniRef50_O97141 Cluster: Nicotinic acetylcholine beta subunit ho... 43 0.012 UniRef50_UPI0000E47589 Cluster: PREDICTED: similar to gamma-amin... 42 0.015 UniRef50_A7S8M2 Cluster: Predicted protein; n=2; Nematostella ve... 42 0.015 UniRef50_A7SDF1 Cluster: Predicted protein; n=2; Nematostella ve... 42 0.020 UniRef50_A7RNN1 Cluster: Predicted protein; n=2; Nematostella ve... 42 0.020 UniRef50_Q6U4B5 Cluster: Nicotinic acetylcholine receptor beta 1... 42 0.027 UniRef50_P54244 Cluster: Acetylcholine receptor subunit alpha-ty... 42 0.027 UniRef50_UPI0000584BCE Cluster: PREDICTED: hypothetical protein;... 41 0.035 UniRef50_Q9NA62 Cluster: Putative uncharacterized protein; n=1; ... 41 0.035 UniRef50_A7RTX5 Cluster: Predicted protein; n=1; Nematostella ve... 41 0.047 UniRef50_Q2PMX5 Cluster: GABA receptor; n=1; Tetranychus urticae... 40 0.062 UniRef50_O17402 Cluster: Putative uncharacterized protein; n=2; ... 40 0.082 UniRef50_A7SDF0 Cluster: Predicted protein; n=2; Nematostella ve... 40 0.082 UniRef50_Q94900 Cluster: Glutamate-gated chloride channel precur... 40 0.082 UniRef50_Q61KY4 Cluster: Putative uncharacterized protein CBG091... 33 0.088 UniRef50_Q9TVI7 Cluster: Putative uncharacterized protein; n=2; ... 40 0.11 UniRef50_O61884 Cluster: Acetylcholine receptor protein 23; n=2;... 40 0.11 UniRef50_A7S2G5 Cluster: Predicted protein; n=1; Nematostella ve... 40 0.11 UniRef50_Q60NW3 Cluster: Putative uncharacterized protein CBG225... 39 0.14 UniRef50_Q0GQQ7 Cluster: PH-sensitive chloride channel variant 4... 39 0.14 UniRef50_P58154 Cluster: Acetylcholine-binding protein precursor... 39 0.14 UniRef50_A7RT31 Cluster: Predicted protein; n=1; Nematostella ve... 39 0.19 UniRef50_A7RF65 Cluster: Predicted protein; n=1; Nematostella ve... 39 0.19 UniRef50_Q9VGI0 Cluster: CG14723-PA, isoform A; n=12; Endopteryg... 38 0.25 UniRef50_Q9U358 Cluster: Putative uncharacterized protein acc-4;... 38 0.25 UniRef50_Q8WSF8 Cluster: Soluble acetylcholine receptor; n=2; Ap... 38 0.25 UniRef50_Q21005 Cluster: Putative uncharacterized protein acc-1;... 38 0.25 UniRef50_A7SFG6 Cluster: Predicted protein; n=4; Nematostella ve... 38 0.33 UniRef50_UPI00015B58ED Cluster: PREDICTED: similar to GABA-gated... 38 0.44 UniRef50_UPI0000DD81A8 Cluster: PREDICTED: SET domain containing... 38 0.44 UniRef50_Q4SXG4 Cluster: Chromosome undetermined SCAF12416, whol... 38 0.44 UniRef50_Q6QWI5 Cluster: Acetylcholine receptor 20 (63.9 kD) alt... 38 0.44 UniRef50_O01792 Cluster: Putative uncharacterized protein; n=2; ... 38 0.44 UniRef50_Q4SGK0 Cluster: Chromosome 3 SCAF14593, whole genome sh... 37 0.58 UniRef50_Q61R47 Cluster: Putative uncharacterized protein CBG067... 37 0.58 UniRef50_UPI0000E46711 Cluster: PREDICTED: similar to Neuronal a... 37 0.76 UniRef50_Q6IGG5 Cluster: HDC06343; n=1; Drosophila melanogaster|... 37 0.76 UniRef50_Q5WN65 Cluster: Putative uncharacterized protein CBG081... 37 0.76 UniRef50_A7SQS7 Cluster: Predicted protein; n=1; Nematostella ve... 37 0.76 UniRef50_UPI000051DDF1 Cluster: ACETYLCHOLINE-BINDING PROTEIN; n... 36 1.0 UniRef50_A7SCG0 Cluster: Predicted protein; n=1; Nematostella ve... 36 1.0 UniRef50_UPI0000E4906F Cluster: PREDICTED: similar to nicotinic ... 36 1.3 UniRef50_Q7YTP9 Cluster: Putative uncharacterized protein; n=2; ... 36 1.3 UniRef50_Q21420 Cluster: Putative uncharacterized protein; n=4; ... 36 1.3 UniRef50_UPI0000DB7771 Cluster: PREDICTED: similar to nicotinic ... 36 1.8 UniRef50_Q08861 Cluster: Gamma-aminobutyric acid-grated chloride... 36 1.8 UniRef50_A7S5Y7 Cluster: Predicted protein; n=1; Nematostella ve... 36 1.8 UniRef50_UPI0000E48167 Cluster: PREDICTED: similar to nicotinic ... 35 2.3 UniRef50_UPI0000E4771F Cluster: PREDICTED: hypothetical protein;... 35 2.3 UniRef50_A7SH22 Cluster: Predicted protein; n=1; Nematostella ve... 35 2.3 UniRef50_UPI0000E81668 Cluster: PREDICTED: similar to Probable p... 35 3.1 UniRef50_UPI0000E4732A Cluster: PREDICTED: similar to nicotinic ... 35 3.1 UniRef50_Q3JT18 Cluster: Flavoprotein reductase; n=2; Burkholder... 35 3.1 UniRef50_UPI0000E46D49 Cluster: PREDICTED: similar to nicotinic ... 34 4.1 UniRef50_A7RTF6 Cluster: Predicted protein; n=2; Nematostella ve... 34 4.1 UniRef50_Q8EKA6 Cluster: Fibronectin type III domain protein; n=... 34 5.4 UniRef50_Q7NHR7 Cluster: Gll2468 protein; n=1; Gloeobacter viola... 34 5.4 UniRef50_A6W6S5 Cluster: Diguanylate cyclase/phosphodiesterase; ... 34 5.4 UniRef50_A0VAW4 Cluster: Uncharacterized peroxidase-related enzy... 34 5.4 UniRef50_P91985 Cluster: Putative uncharacterized protein; n=1; ... 34 5.4 UniRef50_P54246 Cluster: Acetylcholine receptor subunit alpha-ty... 34 5.4 UniRef50_UPI0001560B17 Cluster: PREDICTED: similar to precursor ... 33 7.1 UniRef50_UPI000041A8E7 Cluster: PREDICTED: similar to Gamma-amin... 33 7.1 UniRef50_Q4STL8 Cluster: Chromosome undetermined SCAF14147, whol... 33 7.1 UniRef50_Q9W4G1 Cluster: CG6927-PA; n=6; Diptera|Rep: CG6927-PA ... 33 7.1 UniRef50_Q9VDU9 Cluster: CG7411-PA; n=12; Endopterygota|Rep: CG7... 33 7.1 UniRef50_Q5XGW2 Cluster: LOC495127 protein; n=2; Xenopus laevis|... 33 9.4 >UniRef50_UPI0000D55EDD Cluster: PREDICTED: similar to CG11822-PA, isoform A; n=1; Tribolium castaneum|Rep: PREDICTED: similar to CG11822-PA, isoform A - Tribolium castaneum Length = 438 Score = 89.0 bits (211), Expect = 1e-16 Identities = 51/184 (27%), Positives = 93/184 (50%), Gaps = 11/184 (5%) Frame = +2 Query: 107 NATSLSLMIDSLLATYDRESPP-----DSKIVVNLTLHLRHANIRESESTVRILADLQMN 271 N+T + LL YD+ + P +K+V LT+ RH + E +ST+ + + ++++ Sbjct: 36 NSTVTDKLRQDLLLNYDKFARPAQHYNTTKVVFGLTI--RHIELNEFKSTLVVHSWIRLS 93 Query: 272 WIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLLNAAATTAGDYA--LRARVSNNGSVSW 442 W D++L WN+ +G T ++ +W+PD+ L N+A ++ + + V G V W Sbjct: 94 WKDEKLQWNSTNYGGLETLNLADHEIWQPDIFLYNSATSSGITHYGNVNCIVYEGGDVLW 153 Query: 443 IKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDK---RIYSMFESGAWDV 613 + S ++ L WP D Q C FGS +N D++D D ++ + E+ W++ Sbjct: 154 VPPAQFSVLCNLNLKYWPFDTQRCEMIFGSWTYNGDQIDIDPDNDGVKMELLIENSEWNI 213 Query: 614 TDLS 625 D S Sbjct: 214 VDKS 217 >UniRef50_Q4S3I4 Cluster: Chromosome 1 SCAF14749, whole genome shotgun sequence; n=2; Euteleostomi|Rep: Chromosome 1 SCAF14749, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 503 Score = 81.8 bits (193), Expect = 2e-14 Identities = 45/136 (33%), Positives = 71/136 (52%), Gaps = 5/136 (3%) Frame = +2 Query: 260 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLL-NAAATTAGDYALRARVSNNGS 433 L WID +L WN ++G T + V SE LW PD+VL NA G +A V NG+ Sbjct: 64 LCQEWIDYKLRWNPDKYGGITSIRVPSENLWLPDIVLYENADGRFEGSLMTKAIVRYNGA 123 Query: 434 VSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFV-IDKRI--YSMFESGA 604 ++W + +M + +P D Q CT KFGS ++ +D + IDK++ F++G Sbjct: 124 ITWTPPASYKSACTMDVTFFPFDRQNCTMKFGSWTYDGTMVDLILIDKQVDRKDFFDNGE 183 Query: 605 WDVTDLSSAVXSQDRG 652 W++ + A ++ G Sbjct: 184 WEILSATGAKGNRKDG 199 >UniRef50_Q2XWK6 Cluster: Nicotinic acetylcholine receptor subunit type G; n=1; Lymnaea stagnalis|Rep: Nicotinic acetylcholine receptor subunit type G - Lymnaea stagnalis (Great pond snail) Length = 618 Score = 79.0 bits (186), Expect = 1e-13 Identities = 53/178 (29%), Positives = 90/178 (50%), Gaps = 12/178 (6%) Frame = +2 Query: 125 LMIDSLLATYDRESPP--DSKIVVNLTLHLRHANIRESESTVRILAD---LQMNWIDKRL 289 L+++ LLA Y R S P ++ + V + L I + + ++L L+ W+D+RL Sbjct: 90 LLMERLLARYHRYSRPVMNASLSVQVKFGLTLVQISDMDEVNQVLTINVWLEQEWVDERL 149 Query: 290 SWNAGEWGCSTWL-VSSERLWRPDVVLLNAAAT-TAGDYALRARVSNNGSVSWIKRLDIS 463 +W+ E+ L + E+LW PD+VL N+A T G +A V +NG+V W Sbjct: 150 TWSPKEYNNLHILRIPCEKLWLPDIVLYNSADDYTTGYMNSKAMVQHNGTVFWPPPAKFR 209 Query: 464 TPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDF-----VIDKRIYSMFESGAWDVTDL 622 + + + +P D QTC KFGS ++ ++D +D + Y SG W++ D+ Sbjct: 210 SSCKIDITYFPFDDQTCELKFGSWTYDGFQVDITNRSATVDLQNYVF--SGEWELMDV 265 >UniRef50_Q4S3I6 Cluster: Chromosome 1 SCAF14749, whole genome shotgun sequence; n=1; Tetraodon nigroviridis|Rep: Chromosome 1 SCAF14749, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 340 Score = 78.2 bits (184), Expect = 3e-13 Identities = 56/191 (29%), Positives = 87/191 (45%), Gaps = 9/191 (4%) Frame = +2 Query: 77 CAIASAAECENATSLSLMIDSLLATYDRESPPDSK---IVVNLTL-HLRHANIRESESTV 244 C AS AE E L+ R + +S+ I + ++L L H N R+ T Sbjct: 1 CTAASCAEVEERLVSHLLAPDRYNKLIRPAVNNSQQVTIYIQVSLAQLIHVNERDQIMTT 60 Query: 245 RILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARV 418 L W D RL WN E+ G + ++ +W PD+VL N A T Y A + Sbjct: 61 NCW--LSQVWYDYRLMWNPEEYEGIKKIRLPTQHIWLPDIVLYNNADGTYEVSYYSNAVI 118 Query: 419 SNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDKRIYSMFE- 595 SNNG V+W+ + +++ ++P D Q CT +F S ++ E+D ++ S + Sbjct: 119 SNNGEVNWLPPAIYKSACKIEVRDFPFDQQNCTLQFRSWTYDHTEIDLILVSDYASRDDF 178 Query: 596 --SGAWDVTDL 622 SG WD+ L Sbjct: 179 KPSGEWDIVSL 189 >UniRef50_A7RFJ5 Cluster: Predicted protein; n=2; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 328 Score = 76.2 bits (179), Expect = 1e-12 Identities = 49/179 (27%), Positives = 90/179 (50%), Gaps = 12/179 (6%) Frame = +2 Query: 125 LMIDSLLATYDRESPP--DSKIVVNLTLHL-RHANIRESESTVRILADLQMNWIDKRLSW 295 +++ L YDR+ P ++ +VV L R A + E + V L+ W++ LSW Sbjct: 8 ILLRYLFTNYDRDIHPGGNNPVVVTFGAKLGRIAAVDEKNNVVLAHWYLKQKWVNPSLSW 67 Query: 296 NAGEWG-CSTWLVSSERLWRPDVVLLNAAATT---AGDYALRARVSN--NGSVSWIKRLD 457 NA E+G +T V +RLW PD+VL N A AG + + ++ +G++ W+ Sbjct: 68 NASEFGGVNTLHVEPDRLWVPDIVLYNNADPKNDLAGGFQYKTKIEMQADGTMIWLAPAM 127 Query: 458 ISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVID---KRIYSMFESGAWDVTDLS 625 + M + +P D Q+C +F S M+++ +++ ID ++ F + W++ L+ Sbjct: 128 FHSACPMDIRYFPFDEQSCDLQFASWMYDTSKLEMKIDANETKVMDTFTNKEWEIPKLT 186 >UniRef50_Q27218 Cluster: Acetylcholine receptor subunit beta-type lev-1 precursor; n=6; Caenorhabditis|Rep: Acetylcholine receptor subunit beta-type lev-1 precursor - Caenorhabditis elegans Length = 507 Score = 74.9 bits (176), Expect = 2e-12 Identities = 51/176 (28%), Positives = 86/176 (48%), Gaps = 6/176 (3%) Frame = +2 Query: 161 ESPPDSKIVVNLTLHLRHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSS 337 E P KI + L L + N+ E E + L M W D +L W+ ++ T + V+ Sbjct: 61 ELPMIVKIGMQLVLLI---NVDEKEQVMHTNVWLTMKWDDFQLKWDPRDYANITQIRVAP 117 Query: 338 ERLWRPDVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTC 514 E++W PD+VL N A + + + G+V W+ + + ++ +P D Q C Sbjct: 118 EKVWLPDIVLFNNADGNYEVSFMCNVLILSTGTVLWVPPAIYKSSCIIDVEFFPFDDQLC 177 Query: 515 TFKFGSRMHNSDE--MDFVIDKRI-YSMFE-SGAWDVTDLSSAVXSQDRGEVEARV 670 + FGS +N DE +DF+ R+ +S + S WD+ D AV + DR +E ++ Sbjct: 178 SLTFGSWTYNRDEIKLDFLTSDRVDFSEYSTSSIWDMMD-GPAVLTSDRSRIEFQI 232 >UniRef50_P48182 Cluster: Acetylcholine receptor subunit beta-type acr-2 precursor; n=3; Rhabditida|Rep: Acetylcholine receptor subunit beta-type acr-2 precursor - Caenorhabditis elegans Length = 575 Score = 73.3 bits (172), Expect = 7e-12 Identities = 43/142 (30%), Positives = 71/142 (50%), Gaps = 7/142 (4%) Frame = +2 Query: 218 NIRESESTVRILADLQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLLNAA-ATTA 391 N+ E ++ L M W D +L+WN E+G S V S+R+W PD+VL N A Sbjct: 99 NVDEKNQILQTNVWLTMKWNDFQLAWNPAEYGNISNLHVPSDRVWLPDIVLFNNADGNYE 158 Query: 392 GDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEM----- 556 + V ++G V+W+ + + ++ +P D Q CT FGS +NS+E+ Sbjct: 159 VSFKSNVFVDHHGDVTWVPPAMFKSSCRIDVEWFPFDEQCCTLVFGSWTYNSEEVRLHWY 218 Query: 557 DFVIDKRIYSMFESGAWDVTDL 622 + + +++ SG WDV D+ Sbjct: 219 NNIQAVQLHDYSYSGIWDVIDV 240 >UniRef50_P30532 Cluster: Neuronal acetylcholine receptor subunit alpha-5 precursor; n=70; Euteleostomi|Rep: Neuronal acetylcholine receptor subunit alpha-5 precursor - Homo sapiens (Human) Length = 468 Score = 72.9 bits (171), Expect = 9e-12 Identities = 43/179 (24%), Positives = 85/179 (47%), Gaps = 11/179 (6%) Frame = +2 Query: 128 MIDSLLATYDRESPP----DSKIVVNLTLHLRH-ANIRESESTVRILADLQMNWIDKRLS 292 ++ L Y+R P + KI + L + ++ E + L+ WID +L Sbjct: 50 LLKDLFQDYERWVRPVEHLNDKIKIKFGLAISQLVDVDEKNQLMTTNVWLKQEWIDVKLR 109 Query: 293 WNAGEWG-CSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVSWIKRLDISTP 469 WN ++G V S+ +W PD+VL + A + + + NG+V+W + + Sbjct: 110 WNPDDYGGIKVIRVPSDSVWTPDIVLFDNADGRFEGTSTKTVIRYNGTVTWTPPANYKSS 169 Query: 470 ISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFV-----IDKRIYSMFESGAWDVTDLSSA 631 ++ + +P D+Q C+ KFGS ++ ++D + +DKR F++G W++ + + Sbjct: 170 CTIDVTFFPFDLQNCSMKFGSWTYDGSQVDIILEDQDVDKR--DFFDNGEWEIVSATGS 226 >UniRef50_Q4S864 Cluster: Chromosome 5 SCAF14709, whole genome shotgun sequence; n=3; Tetraodontidae|Rep: Chromosome 5 SCAF14709, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 733 Score = 72.1 bits (169), Expect = 2e-11 Identities = 39/121 (32%), Positives = 62/121 (51%), Gaps = 5/121 (4%) Frame = +2 Query: 272 WIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGSVSWI 445 W D +L WN E+G ++ V S R+W+PD+VL N A D +A + NG V+WI Sbjct: 233 WNDYKLRWNPKEYGGVEYIRVPSSRIWKPDIVLYNNAVGDFQVDDKTKALLRYNGDVTWI 292 Query: 446 KRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVI---DKRIYSMFESGAWDVT 616 + + + +P D Q CT KFGS ++ ++D V+ + +E+G W + Sbjct: 293 PPAIFKSSCKIDVTYFPFDYQNCTMKFGSWTYDKAKIDLVLIGSTMNLKDFWETGDWLII 352 Query: 617 D 619 D Sbjct: 353 D 353 Score = 62.1 bits (144), Expect = 2e-08 Identities = 39/120 (32%), Positives = 60/120 (50%), Gaps = 2/120 (1%) Frame = +2 Query: 179 KIVVNLTLHLRHANIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 355 K+ V+L L N RE T + L +W+D RLSW+ ++ G + + S +W P Sbjct: 37 KLQVSLA-QLISVNEREQIMTTNLW--LMQHWVDYRLSWDPAKYEGINKLRIPSRLIWLP 93 Query: 356 DVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 532 D+VL N A T A V NGS++W+ + +++ ++P D Q CT KF S Sbjct: 94 DIVLYNNADGTYEVTVYTNAIVLFNGSINWLPPAIYKSACKIEVKHFPFDQQNCTLKFRS 153 >UniRef50_UPI00015A3E3C Cluster: Neuronal acetylcholine receptor subunit alpha-4 precursor.; n=1; Danio rerio|Rep: Neuronal acetylcholine receptor subunit alpha-4 precursor. - Danio rerio Length = 556 Score = 71.7 bits (168), Expect = 2e-11 Identities = 49/187 (26%), Positives = 96/187 (51%), Gaps = 15/187 (8%) Frame = +2 Query: 101 CENATSLSLMIDSLLATYDRESPPDSKI--VVNLTLHLRHANIRESESTVRILAD---LQ 265 C+ + +++SLL+ Y + + P + VV++ L A + + + +++ ++ Sbjct: 24 CDEVQAEERLLNSLLSAYSKLTRPVHSVSDVVHVHFGLSIAQLIDVDEKNQMMTTNVWVK 83 Query: 266 MNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNG 430 W+D RL W + G S+ + ++ +W+PD+VL N A GD+ + +A + ++G Sbjct: 84 QEWLDYRLRWTPEDNGNVSSMRIPAQFIWKPDIVLYNNAD---GDFTVTHLTKAHLLHDG 140 Query: 431 SVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFV-----IDKRIYSMFE 595 V+WI + S+ + P D Q CT KFGS ++ ++D + +D+ Y +E Sbjct: 141 RVTWIPPAIYKSSCSIDVTFLPFDQQNCTIKFGSWTYDRSKIDLIRIADSVDQLDY--WE 198 Query: 596 SGAWDVT 616 SG W +T Sbjct: 199 SGEWLIT 205 >UniRef50_Q2XWK8 Cluster: Nicotinic acetylcholine receptor subunit type E; n=16; Protostomia|Rep: Nicotinic acetylcholine receptor subunit type E - Lymnaea stagnalis (Great pond snail) Length = 538 Score = 70.5 bits (165), Expect = 5e-11 Identities = 44/135 (32%), Positives = 70/135 (51%), Gaps = 6/135 (4%) Frame = +2 Query: 179 KIVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWR 352 K+VV + + L +I E + L+ W DK+L+W A E+G L V SE +W Sbjct: 56 KLVVKMGIRLSQLIDIDEKNQIMTTNVWLRQEWTDKKLTWQASEYGGVDHLYVPSEHIWL 115 Query: 353 PDVVLLNAAATTAGDYAL----RARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTF 520 PD+VL N A G+Y + +A V + G V W + ++ ++ +P D Q+C Sbjct: 116 PDIVLYNNAD---GNYEVTLMTKATVHSTGLVVWEPPAIYKSSCTINVEFFPFDEQSCKM 172 Query: 521 KFGSRMHNSDEMDFV 565 KFGS ++ D++D V Sbjct: 173 KFGSWTYDGDQVDLV 187 >UniRef50_A7S3F7 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 334 Score = 70.5 bits (165), Expect = 5e-11 Identities = 49/178 (27%), Positives = 85/178 (47%), Gaps = 11/178 (6%) Frame = +2 Query: 128 MIDSLLATYDRESPP---DSKIV-VNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLS 292 +I LL TY+ + P D+ V + LT+ L+ ++ E ++ L+ W D RL+ Sbjct: 7 LIHDLLDTYNPRARPVTNDNHTVGLKLTIRLQQIMDVDEKNEVIQTFLILEQMWNDTRLA 66 Query: 293 WNAGEWG-CSTWLVSSERLWRPDVVLLNAAATTAG--DYALRARVSNNGSVSWIKRLDIS 463 WN E+G + S+ +W PD+ +LN+A + +R +++ G V W+ L + Sbjct: 67 WNETEYGGIKQMTLRSKLIWTPDISVLNSANKDMDLREKNIRLFINSAGEVLWMNPLILH 126 Query: 464 TPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD---FVIDKRIYSMFESGAWDVTDLSS 628 T M + ++P D Q C +FGS + MD F + E+G W + +S Sbjct: 127 TSCGMDIAHFPFDNQACELRFGSWSTSLRYMDVHPFEDTANLQYFVENGEWILESTTS 184 >UniRef50_UPI0001560C7D Cluster: PREDICTED: similar to cholinergic receptor, nicotinic, alpha 2 (neuronal); n=2; Laurasiatheria|Rep: PREDICTED: similar to cholinergic receptor, nicotinic, alpha 2 (neuronal) - Equus caballus Length = 630 Score = 70.1 bits (164), Expect = 7e-11 Identities = 49/173 (28%), Positives = 82/173 (47%), Gaps = 9/173 (5%) Frame = +2 Query: 152 YDRESPPDSKIV-VNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTW 325 Y R P S +V V L + ++ E + L+ W D +L WN ++G T Sbjct: 71 YARPVPNTSDVVIVRFGLSIAQLIDVDEKNQMMTTNVWLKQEWSDYKLRWNPADFGNITS 130 Query: 326 L-VSSERLWRPDVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPN 499 L V SE +W PD+VL N A A + +A + + G+V W+ + S+ + +P Sbjct: 131 LRVPSEMIWIPDIVLYNNADGEFAVTHMTKAHLFSTGTVHWVPPAIYKSSCSIDVTFFPF 190 Query: 500 DMQTCTFKFGSRMHNS-----DEMDFVIDKRIYSMFESGAWDVTDLSSAVXSQ 643 D Q C KFGS ++ ++M+ +D + Y +ESG W + + + S+ Sbjct: 191 DQQNCKMKFGSWTYDKAKIDLEQMEQTVDLKDY--WESGEWAIINATGTYNSK 241 >UniRef50_Q15822 Cluster: Neuronal acetylcholine receptor subunit alpha-2 precursor; n=98; Euteleostomi|Rep: Neuronal acetylcholine receptor subunit alpha-2 precursor - Homo sapiens (Human) Length = 529 Score = 69.7 bits (163), Expect = 9e-11 Identities = 41/135 (30%), Positives = 69/135 (51%), Gaps = 7/135 (5%) Frame = +2 Query: 260 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAA-ATTAGDYALRARVSNNGS 433 L+ W D +L WN ++G T L V SE +W PD+VL N A A + +A + + G+ Sbjct: 111 LKQEWSDYKLRWNPADFGNITSLRVPSEMIWIPDIVLYNNADGEFAVTHMTKAHLFSTGT 170 Query: 434 VSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNS-----DEMDFVIDKRIYSMFES 598 V W+ + S+ + +P D Q C KFGS ++ ++M+ +D + Y +ES Sbjct: 171 VHWVPPAIYKSSCSIDVTFFPFDQQNCKMKFGSWTYDKAKIDLEQMEQTVDLKDY--WES 228 Query: 599 GAWDVTDLSSAVXSQ 643 G W + + + S+ Sbjct: 229 GEWAIVNATGTYNSK 243 >UniRef50_P43681 Cluster: Neuronal acetylcholine receptor subunit alpha-4 precursor; n=35; Euteleostomi|Rep: Neuronal acetylcholine receptor subunit alpha-4 precursor - Homo sapiens (Human) Length = 627 Score = 69.3 bits (162), Expect = 1e-10 Identities = 55/202 (27%), Positives = 101/202 (50%), Gaps = 14/202 (6%) Frame = +2 Query: 56 LLPFLLTCAIASAAECEN-ATSLSLMIDSLLATYDRESPPDSKI--VVNLTLHLRHANIR 226 LL L T + +++ E A + ++ L + Y++ S P + I VV + L A + Sbjct: 15 LLLLLGTGLLRASSHVETRAHAEERLLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLI 74 Query: 227 ESESTVRILAD---LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAG 394 + + +++ ++ W D +L W+ ++ T + + SE +WRPD+VL N A G Sbjct: 75 DVDEKNQMMTTNVWVKQEWHDYKLRWDPADYENVTSIRIPSELIWRPDIVLYNNAD---G 131 Query: 395 DYAL----RARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDF 562 D+A+ +A + ++G V W + S+ + +P D Q CT KFGS ++ ++D Sbjct: 132 DFAVTHLTKAHLFHDGRVQWTPPAIYKSSCSIDVTFFPFDQQNCTMKFGSWTYDKAKIDL 191 Query: 563 V-IDKRI--YSMFESGAWDVTD 619 V + R+ +ESG W + D Sbjct: 192 VNMHSRVDQLDFWESGEWVIVD 213 >UniRef50_Q60KR8 Cluster: Putative uncharacterized protein CBG23934; n=1; Caenorhabditis briggsae|Rep: Putative uncharacterized protein CBG23934 - Caenorhabditis briggsae Length = 551 Score = 68.9 bits (161), Expect = 2e-10 Identities = 43/167 (25%), Positives = 80/167 (47%), Gaps = 8/167 (4%) Frame = +2 Query: 89 SAAECENATSLSLMIDSLLATYDRES-PPDSK----IVVNLTLHLRH-ANIRESESTVRI 250 S + + T+ + ++LL+ Y+R + PP K + + L L ++ E + + + Sbjct: 10 SLFKLNDCTAYKNLFETLLSRYNRIAFPPGEKHNNSLKIEFKLRLDQIVDVHEKDQVITL 69 Query: 251 LADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAG-DYALRARVSN 424 L W D RLSWN E+G T + E +W PD++L N A + + VS+ Sbjct: 70 KGILVHRWHDIRLSWNPQEFGDITLMHFPGEMIWLPDIILYNNAHGSPWVSETTQVHVSH 129 Query: 425 NGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFV 565 G V+W + ++ ++ +P D+Q C KFGS + +++ + Sbjct: 130 EGRVTWHPPVAYDAFCNIDIEWYPYDLQICELKFGSWTYGGSQLNLI 176 >UniRef50_Q5BW84 Cluster: SJCHGC08361 protein; n=1; Schistosoma japonicum|Rep: SJCHGC08361 protein - Schistosoma japonicum (Blood fluke) Length = 213 Score = 68.9 bits (161), Expect = 2e-10 Identities = 39/152 (25%), Positives = 73/152 (48%), Gaps = 8/152 (5%) Frame = +2 Query: 131 IDSLLATYDRESPP----DSKIVVNLTLHLRH-ANIRESESTVRILADLQMNWIDKRLSW 295 ID+L+ Y+ P K+ V +++ L+ + E + + L+ W D L W Sbjct: 16 IDTLMKNYESSVRPLKNISEKLTVKISIRLQQIGGLNERNQVLTTILFLEQIWEDDYLKW 75 Query: 296 NAGEWG-CSTWLVSSERLWRPDVVLLNAAATTAGDY--ALRARVSNNGSVSWIKRLDIST 466 N E+G T + ++++W PD + N A T + + + ++G VSW + + T Sbjct: 76 NESEFGNVRTLRIPAKQVWTPDTYVFNNADHTNSGFLEGIYVIIHSSGKVSWPIPVQLKT 135 Query: 467 PISMQLDNWPNDMQTCTFKFGSRMHNSDEMDF 562 + + +P D Q C +FGS M+ SD +++ Sbjct: 136 SCKVDITLFPFDHQNCEIQFGSWMYKSDWIEY 167 >UniRef50_Q2XWL1 Cluster: Nicotinic acetylcholine receptor subunit type B; n=1; Lymnaea stagnalis|Rep: Nicotinic acetylcholine receptor subunit type B - Lymnaea stagnalis (Great pond snail) Length = 527 Score = 68.9 bits (161), Expect = 2e-10 Identities = 39/125 (31%), Positives = 67/125 (53%), Gaps = 8/125 (6%) Frame = +2 Query: 269 NWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLLNAAATTAGDYALRARV-SNNGSVSW 442 +WID L+WN E+G +T V+++ +W+PD+ L N A T + V S+NG V W Sbjct: 88 SWIDMYLAWNESEYGNITTVRVNNDDIWKPDIKLYNYADTRLEEKREALCVLSSNGEVVW 147 Query: 443 IKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVI---DKRIYSMFE---SGA 604 I + + S+ + ++P D+Q C KFGS ++ ++D D + + M + S Sbjct: 148 IPQAVFKSSCSIDIRHFPFDVQRCDMKFGSWTYDGSKLDIQFRYPDVKGFEMDDYIVSNE 207 Query: 605 WDVTD 619 WD+ + Sbjct: 208 WDIVE 212 >UniRef50_Q17BK7 Cluster: Nicotinic acetylcholine receptor, beta-2 subunit, putative; n=1; Aedes aegypti|Rep: Nicotinic acetylcholine receptor, beta-2 subunit, putative - Aedes aegypti (Yellowfever mosquito) Length = 434 Score = 68.9 bits (161), Expect = 2e-10 Identities = 44/149 (29%), Positives = 73/149 (48%), Gaps = 8/149 (5%) Frame = +2 Query: 140 LLATYDRESPP--DSKIVVNLTLHLRHANIRESESTVRILADL--QMNWIDKRLSWNAGE 307 L +YD P D K VN+++ + EST + A++ M WID+ L W++ E Sbjct: 41 LCNSYDANQRPVKDIKFAVNVSVLPVLMSFEYDESTNALNANMLVTMEWIDENLKWDSKE 100 Query: 308 WGCSTWL-VSSERLWRPDVVLLNAAA---TTAGDYALRARVSNNGSVSWIKRLDISTPIS 475 + T + +SS+++W PD L ++ T LR+ V +G+V + D S Sbjct: 101 YNNQTTIAISSDQIWTPDFQLYSSTVKFDTKQSCTNLRSLVKYDGTVIAVPTCDFSARCE 160 Query: 476 MQLDNWPNDMQTCTFKFGSRMHNSDEMDF 562 +WP D Q C FG+ M ++ E+D+ Sbjct: 161 ADYTDWPLDTQRCRMLFGAWMEHAGEVDY 189 >UniRef50_P17787 Cluster: Neuronal acetylcholine receptor subunit beta-2 precursor; n=69; Euteleostomi|Rep: Neuronal acetylcholine receptor subunit beta-2 precursor - Homo sapiens (Human) Length = 502 Score = 68.9 bits (161), Expect = 2e-10 Identities = 44/153 (28%), Positives = 72/153 (47%), Gaps = 6/153 (3%) Frame = +2 Query: 182 IVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 355 + V L + L ++ E E + L W D RL+W E+ + S+ +W P Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115 Query: 356 DVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 532 DVVL N A + A VS +GS+ W+ + +++ ++P D Q CT KF S Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRS 175 Query: 533 RMHNSDEMDFVIDKRIYSMFE---SGAWDVTDL 622 ++ E+D V+ + S+ + SG WD+ L Sbjct: 176 WTYDRTEIDLVLKSEVASLDDFTPSGEWDIVAL 208 >UniRef50_UPI0000E49844 Cluster: PREDICTED: similar to nicotinic acetylcholine receptor alpha2 subunit; n=1; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to nicotinic acetylcholine receptor alpha2 subunit - Strongylocentrotus purpuratus Length = 570 Score = 68.5 bits (160), Expect = 2e-10 Identities = 53/209 (25%), Positives = 102/209 (48%), Gaps = 15/209 (7%) Frame = +2 Query: 32 KMSTTY-IILLPFLLTCAIASAAE-CENATSLSLMIDSLLATYDRESPP--DSKIVVNLT 199 + TT+ +I+ FL+ I + A+ C ++ + + L Y+R P ++ V+++ Sbjct: 48 RTGTTFSLIMKSFLVAIMILAFAQGCTSSEAEERLFTKLFYKYNRLIRPVENNSEVLDVN 107 Query: 200 LHLRHANIRESESTVRILAD---LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVL 367 L + + + + +I+ L+ W+D +L WN E+ S V S+ +W PD+VL Sbjct: 108 FRLTMSQLIDVDEKNQIMTTNVWLKQLWMDYKLQWNPAEYDNISILRVPSKMIWTPDLVL 167 Query: 368 LNAAATTAGDYAL----RARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSR 535 N A G+Y + +A V ++G+V W+ + + + +P D Q C KFGS Sbjct: 168 YNNAD---GNYEVTLMAKALVYSDGTVYWLPPAIYKSSCKINVRYFPFDEQFCPMKFGSW 224 Query: 536 MHNSDEMDFV---IDKRIYSMFESGAWDV 613 ++ +D + D + ++SG WD+ Sbjct: 225 TYDGSLIDLIPSSNDVDLEDYWQSGEWDI 253 >UniRef50_UPI0000E49401 Cluster: PREDICTED: similar to alpha 10 subunit of nicotinic acetylcholine receptor; n=1; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to alpha 10 subunit of nicotinic acetylcholine receptor - Strongylocentrotus purpuratus Length = 347 Score = 68.5 bits (160), Expect = 2e-10 Identities = 32/105 (30%), Positives = 57/105 (54%), Gaps = 2/105 (1%) Frame = +2 Query: 257 DLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATT-AGDYALRARVSNNG 430 +LQ W D L WN ++G T + + S +W+PD++L N A ++ G A VSN+G Sbjct: 87 NLQFEWSDPNLKWNPDDYGGITKITIPSSNIWKPDILLYNNADSSFKGAMKTNAAVSNDG 146 Query: 431 SVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFV 565 V+W + + ++ +P D Q CT +FGS + ++ ++ + Sbjct: 147 IVTWFAPAIFRSSCKININYFPFDKQECTLQFGSWAYTTEHLNLL 191 >UniRef50_Q7T2R4 Cluster: Nicotinic acetylcholine receptor alpha 9d subunit; n=7; Clupeocephala|Rep: Nicotinic acetylcholine receptor alpha 9d subunit - Fugu rubripes (Japanese pufferfish) (Takifugu rubripes) Length = 521 Score = 68.5 bits (160), Expect = 2e-10 Identities = 43/152 (28%), Positives = 76/152 (50%), Gaps = 7/152 (4%) Frame = +2 Query: 125 LMIDSLLATYDRESPP--DSKIVVNLTLHLRHANIRESESTVRILAD---LQMNWIDKRL 289 LM D L + Y P D+ ++N+TL + + I + + +IL ++ W+D L Sbjct: 12 LMTD-LFSNYTNALRPVEDTDHIINVTLQITLSQIIDMDERNQILTTYLWVRQVWMDAYL 70 Query: 290 SWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATT-AGDYALRARVSNNGSVSWIKRLDIS 463 +W ++ G T + S +WRPD+VL N+A + + ++G V W + Sbjct: 71 TWKKEDYDGLDTIRIPSSYVWRPDIVLYNSADDEFSSSMETNVVLRHDGQVMWDQPAITK 130 Query: 464 TPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 559 + S+ + ++P D+Q C FGS HN ++MD Sbjct: 131 SSCSVDVAHFPFDLQECHLTFGSWTHNGNQMD 162 >UniRef50_Q4RIA9 Cluster: Chromosome 8 SCAF15044, whole genome shotgun sequence; n=3; Clupeocephala|Rep: Chromosome 8 SCAF15044, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 549 Score = 68.1 bits (159), Expect = 3e-10 Identities = 45/153 (29%), Positives = 73/153 (47%), Gaps = 6/153 (3%) Frame = +2 Query: 182 IVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 355 + V L + L ++ E E + L W D RL+W E+ G + S+ +W P Sbjct: 30 VTVQLMVSLAQLISVHEREQVMTTNVWLTQEWQDYRLTWIPEEFDGMLKVRLPSKHIWLP 89 Query: 356 DVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 532 DVVL N A + A VS +GS+ W+ + +++ ++P D Q CT +F S Sbjct: 90 DVVLYNNADGVYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTLRFRS 149 Query: 533 RMHNSDEMDFVIDKRIYSMFE---SGAWDVTDL 622 ++ E+D V+ + SM + SG WD+ L Sbjct: 150 WTYDRTEIDLVLRADVASMDDFTPSGEWDIIAL 182 >UniRef50_A7RHV9 Cluster: Predicted protein; n=3; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 336 Score = 67.7 bits (158), Expect = 4e-10 Identities = 43/153 (28%), Positives = 79/153 (51%), Gaps = 12/153 (7%) Frame = +2 Query: 191 NLTLHLRHANIRESESTVRILAD---LQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPD 358 N+TL + +I + + +IL+ ++ +WI + LSW+ E+G + +VSS+ LW+PD Sbjct: 38 NVTLDITFNSIIDVDEKHQILSSSVWIRQSWIAETLSWDPAEYGGVNQIVVSSQLLWQPD 97 Query: 359 VVLLNAAA----TTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKF 526 VL N + R RV ++G V W T + + ++P D Q C F Sbjct: 98 TVLYNNIFEEFDSRLDTTVTRVRVYSSGFVYWAMPYVFKTMCKIDVTDFPFDSQRCPITF 157 Query: 527 GSRMHNSDEMDFVIDKRIYSM----FESGAWDV 613 G+ ++ +E++ + +KR+ ++ E+G W V Sbjct: 158 GAWQYDQNEVNLINNKRLATVASTRVENGEWTV 190 >UniRef50_P91766 Cluster: Acetylcholine receptor subunit alpha-like precursor; n=31; Coelomata|Rep: Acetylcholine receptor subunit alpha-like precursor - Manduca sexta (Tobacco hawkmoth) (Tobacco hornworm) Length = 516 Score = 67.7 bits (158), Expect = 4e-10 Identities = 45/174 (25%), Positives = 78/174 (44%), Gaps = 9/174 (5%) Frame = +2 Query: 65 FLLTCAIASAAECENATSLSLMIDSLLATYDRESPPDSKIVVNLTLHLR-------HANI 223 + L + A C + D LL+ Y++ P + LT+ ++ N+ Sbjct: 7 YYLHGVVLFATGCAGNPDAKRLYDDLLSNYNKLVRPVLNVSDALTVRIKLKLSQLIDVNL 66 Query: 224 RESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAA-ATTAGD 397 + T + ++ +W D +LSW E+G L V S+ +WRPD+VL N A Sbjct: 67 KNQIMTTNLW--VEQSWYDYKLSWEPREYGGVEMLHVPSDHIWRPDIVLYNNADGNFEVT 124 Query: 398 YALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 559 A +A ++ G V W + + ++ +P D QTC KFGS ++ ++D Sbjct: 125 LATKATLNYTGRVEWRPPAIYKSSCEIDVEYFPFDQQTCVMKFGSWTYDGFQVD 178 >UniRef50_UPI0000EBE733 Cluster: PREDICTED: similar to nicotinic acetylcholine receptor alpha6 subunit; n=2; Bos taurus|Rep: PREDICTED: similar to nicotinic acetylcholine receptor alpha6 subunit - Bos taurus Length = 630 Score = 67.3 bits (157), Expect = 5e-10 Identities = 46/188 (24%), Positives = 87/188 (46%), Gaps = 13/188 (6%) Frame = +2 Query: 101 CENATSLSLMIDSLLATYDRESPPDSKIVVNLTLHL-----RHANIRESESTVRILADLQ 265 C S + L A Y++ P + +T++ + A++ E + L+ Sbjct: 33 CAGCASEERLFHKLFAHYNQFIRPVENVSDPITVYFEVAITQLADVDEVNQIMETNLWLR 92 Query: 266 MNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRAR----VSNNG 430 W D +L W+ E+ G T V +E +W+PD+VL N A GD+ ++ + + +G Sbjct: 93 HIWNDYKLRWDPTEYDGIETLRVPAEMIWKPDIVLYNNAV---GDFQVKGKTKALLKYDG 149 Query: 431 SVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD-FVIDKRI--YSMFESG 601 ++W + M + +P D Q C+ KFGS ++ E+D +I ++ +E+ Sbjct: 150 MITWTPPAIFKSSCPMDITFFPFDHQNCSLKFGSWTYDKAEIDLLIIGSKVDMNEFWENS 209 Query: 602 AWDVTDLS 625 W++ D S Sbjct: 210 EWEIVDAS 217 >UniRef50_Q4RRI3 Cluster: Chromosome 16 SCAF15002, whole genome shotgun sequence; n=3; Euteleostomi|Rep: Chromosome 16 SCAF15002, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 636 Score = 67.3 bits (157), Expect = 5e-10 Identities = 42/172 (24%), Positives = 82/172 (47%), Gaps = 10/172 (5%) Frame = +2 Query: 128 MIDSLLATYDRESPP--DSKIVVNLTLHLRHANIRESESTVRILAD---LQMNWIDKRLS 292 ++ L + Y P D+ ++N+TL + + I + + +IL ++ W+D L Sbjct: 13 LLTDLFSNYTSALRPVEDTHNILNVTLQVTLSQIIDMDERNQILTAYLWIRRVWVDAHLK 72 Query: 293 WNAGEW-GCSTWLVSSERLWRPDVVLLNAAATT-AGDYALRARVSNNGSVSWIKRLDIST 466 WN E+ G T + S +WRPD+VL N A G + ++G ++W + Sbjct: 73 WNKDEYDGLDTIRIPSSYVWRPDIVLYNNADDHFTGPMDTNVVIRHDGQITWDSPAITKS 132 Query: 467 PISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFV--IDKR-IYSMFESGAWDV 613 + + +P D Q C F +GS +N +++D + +D + + E+ W++ Sbjct: 133 SCRVDVSFFPFDAQQCRFTYGSWTYNGNQLDILNALDSADLADLVENVEWEI 184 >UniRef50_Q93329 Cluster: Putative uncharacterized protein lev-8; n=2; Caenorhabditis|Rep: Putative uncharacterized protein lev-8 - Caenorhabditis elegans Length = 531 Score = 67.3 bits (157), Expect = 5e-10 Identities = 44/172 (25%), Positives = 79/172 (45%), Gaps = 7/172 (4%) Frame = +2 Query: 65 FLLTCAIASAAECENATSLSLMIDSLLATYDRESPP----DSKIVVNLTLHL-RHANIRE 229 FLL I +S ++++LL Y++ P + V +L R ++ E Sbjct: 11 FLLVIFILHIVTINANKHVSQLLENLLTDYNKAVRPVHNASDALKVKFGANLCRLIDVDE 70 Query: 230 SESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLL-NAAATTAGDYA 403 + L+M W DK+L+WN +WG ++ + S+++W PD+VL NA Sbjct: 71 VNQVLTTSLWLEMQWYDKKLTWNPTDWGGVEYIHIPSDQIWIPDIVLYNNADGEPHITIT 130 Query: 404 LRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 559 A++ ++G V W + + + +P D QTC KFG ++ + +D Sbjct: 131 SLAKIDHHGRVVWQPPSIYKSFCPINIKYFPYDWQTCEMKFGGWSNDGETLD 182 >UniRef50_A7T134 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 301 Score = 67.3 bits (157), Expect = 5e-10 Identities = 51/184 (27%), Positives = 83/184 (45%), Gaps = 18/184 (9%) Frame = +2 Query: 128 MIDSLLATYDRESPP--DSKIVVNLTLHLRHANI-----RESESTVRILADLQMNWIDKR 286 ++D L YD+ P D VV L L L+ I +E E R+ + W D + Sbjct: 4 LLDQLFQGYDKRVRPVTDPSDVVELKLGLKIQKIVKIDSKEQEMITRVW--VTQVWRDPK 61 Query: 287 LSWNAGEWG-CSTWLVSSERLWRPDVVLLNAA---ATTAGD---YALRARVSNNGSVSWI 445 L W+ + G T V +W PD+ L N A + AG + + V+N G V W Sbjct: 62 LRWDVEKGGGIETIFVDPSEIWTPDISLYNNADDSVSVAGSEKKFQTKIVVANTGKVVWQ 121 Query: 446 KRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDF--VIDKRIYS--MFESGAWDV 613 + S+++ WP D+Q C+ FGS + + ++ + D Y+ +SG WD+ Sbjct: 122 SPATFRSECSIKIRYWPFDVQKCSMTFGSFIFPASALNVTSLYDSSFYTDRFMQSGDWDI 181 Query: 614 TDLS 625 ++S Sbjct: 182 KEVS 185 >UniRef50_P04755 Cluster: Acetylcholine receptor subunit beta-like 1 precursor; n=20; Protostomia|Rep: Acetylcholine receptor subunit beta-like 1 precursor - Drosophila melanogaster (Fruit fly) Length = 521 Score = 67.3 bits (157), Expect = 5e-10 Identities = 37/145 (25%), Positives = 72/145 (49%), Gaps = 10/145 (6%) Frame = +2 Query: 218 NIRESESTVRILADLQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLLNAAATTAG 394 N+ E ++ L++ W D +L W+ ++G + +++W+PD+VL N A G Sbjct: 66 NVNEKNQVMKSNVWLRLVWYDYQLQWDEADYGGIGVLRLPPDKVWKPDIVLFNNAD---G 122 Query: 395 DYALRAR----VSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDF 562 +Y +R + + G V W+ + ++ + +P D QTC KFGS N D++ Sbjct: 123 NYEVRYKSNVLIYPTGEVLWVPPAIYQSSCTIDVTYFPFDQQTCIMKFGSWTFNGDQVSL 182 Query: 563 VI--DKRIYSM---FESGAWDVTDL 622 + +K + ++SG WD+ ++ Sbjct: 183 ALYNNKNFVDLSDYWKSGTWDIIEV 207 >UniRef50_P17644 Cluster: Acetylcholine receptor subunit alpha-like 2 precursor; n=38; Neoptera|Rep: Acetylcholine receptor subunit alpha-like 2 precursor - Drosophila melanogaster (Fruit fly) Length = 576 Score = 67.3 bits (157), Expect = 5e-10 Identities = 56/181 (30%), Positives = 84/181 (46%), Gaps = 12/181 (6%) Frame = +2 Query: 53 ILLPFLLTCAIASAAECENATSLSLMIDSLLATYDRESPPDSK----IVVNLTLHLRHA- 217 +LL LL C A N + L D LL+ Y+R P S ++V L L L Sbjct: 28 LLLVLLLLCETVQA----NPDAKRLY-DDLLSNYNRLIRPVSNNTDTVLVKLGLRLSQLI 82 Query: 218 --NIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATT 388 N+++ T + L+ W D + W+ E+G T L V SE +W PD+VL N A Sbjct: 83 DLNLKDQILTTNVW--LEHEWQDHKFKWDPSEYGGVTELYVPSEHIWLPDIVLYNNAD-- 138 Query: 389 AGDYAL----RARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEM 556 G+Y + +A + G V W + + + +P D QTC KFGS ++ D++ Sbjct: 139 -GEYVVTTMTKAILHYTGKVVWTPPAIFKSSCEIDVRYFPFDQQTCFMKFGSWTYDGDQI 197 Query: 557 D 559 D Sbjct: 198 D 198 >UniRef50_A7RLP3 Cluster: Predicted protein; n=3; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 417 Score = 66.9 bits (156), Expect = 6e-10 Identities = 49/187 (26%), Positives = 85/187 (45%), Gaps = 15/187 (8%) Frame = +2 Query: 140 LLATYDR---ESPPDSKIVVNLTLH-LRHANIRESESTVRILADLQMNWIDKRLSWNAGE 307 LL YD+ S PD ++ +N +L ++ ++++ E V + MNWI+ L W+ + Sbjct: 20 LLDGYDKVVLPSEPD-RLALNFSLKFVQIMDVKDKEQLVSVECWYSMNWINSFLKWDKKK 78 Query: 308 W-GCSTWLVSSERLWRPDVVLLN----AAATTAG--DYALRARVSNNGSVSWIKRLDIST 466 + S +W PD+ L N T+ G + V + G W + + Sbjct: 79 YQNESRVFFDPSEIWVPDIALYNNGDDKVQTSGGRTKFLTNIVVEDTGKCVWSGPVTFTF 138 Query: 467 PISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDK----RIYSMFESGAWDVTDLSSAV 634 SM L WP D Q CT KFGS + + +F+I K + E+ W++ +++ A+ Sbjct: 139 TCSMALSRWPFDDQNCTMKFGSLSYGKN--NFIISKVKVSKSDDFIENSNWELKNITVAL 196 Query: 635 XSQDRGE 655 D G+ Sbjct: 197 QETDHGD 203 >UniRef50_UPI00015B4A35 Cluster: PREDICTED: similar to nicotinic acetylcholine receptor alpha9 subunit; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to nicotinic acetylcholine receptor alpha9 subunit - Nasonia vitripennis Length = 431 Score = 66.5 bits (155), Expect = 8e-10 Identities = 48/186 (25%), Positives = 79/186 (42%), Gaps = 9/186 (4%) Frame = +2 Query: 32 KMSTTYIILLPFLLTCAIASAAECENATSLSLMIDS-LLATYDRESPP--DSKIVVNLTL 202 ++S ++L L A +A S +L + L YD P VN+++ Sbjct: 2 RLSLVLLLLAAVGLCRAATDTCNILSAKSPTLRLKRHLFCEYDTSIRPVLSKNTAVNVSV 61 Query: 203 HLRHA--NIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLN 373 +R N + +ST + A + W D+ L+W ++ G V S+ +W PD L N Sbjct: 62 VIRPMLMNFIDDKSTFILHAWISFEWTDQHLTWKPEDFDGVQETRVKSDEIWVPDFALYN 121 Query: 374 AA---ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHN 544 + + G ++S+ GSV + + T WP D QTCT + GS H Sbjct: 122 SGDMETSQTGIPETLCQLSHTGSVICLPSIKYKTLCESDFTYWPYDKQTCTLRMGSWTHT 181 Query: 545 SDEMDF 562 +E+ F Sbjct: 182 GEEISF 187 >UniRef50_UPI0000E47D8F Cluster: PREDICTED: similar to nicotinic acetylcholine receptor alpha 7c subunit; n=1; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to nicotinic acetylcholine receptor alpha 7c subunit - Strongylocentrotus purpuratus Length = 257 Score = 66.5 bits (155), Expect = 8e-10 Identities = 39/133 (29%), Positives = 68/133 (51%), Gaps = 4/133 (3%) Frame = +2 Query: 227 ESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLL-NAAATTAGDY 400 E E + I ++ W D+ L W+ + G + VS +++W PD+ L N + Sbjct: 19 EMEQRITINGWRKLQWRDEFLGWDKETYDGIDSLEVSPDKIWLPDIKLYENIDKDFQSED 78 Query: 401 ALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDF-VIDKR 577 A+ A V+N+G V+W + IS+ + + +P D+QTCT FGS + D ++ D Sbjct: 79 AVNALVTNDGMVTWYTPMVISSSCKINVRYFPFDVQTCTLTFGSWAYTIDSLNLNYSDDA 138 Query: 578 IYSMF-ESGAWDV 613 ++F +G WD+ Sbjct: 139 TQNVFLNNGVWDL 151 >UniRef50_O44497 Cluster: Putative uncharacterized protein; n=2; Caenorhabditis|Rep: Putative uncharacterized protein - Caenorhabditis elegans Length = 445 Score = 66.5 bits (155), Expect = 8e-10 Identities = 34/151 (22%), Positives = 67/151 (44%), Gaps = 2/151 (1%) Frame = +2 Query: 89 SAAECENATSLSLMIDSLLATYDRESPPDSKIVVNLTLHLRHANIRESESTVRILADLQM 268 S C+ + + TY + +K+V ++ + + I E V++ + Sbjct: 54 SCHSCQGGDRAWKLRTHIQTTYQNATDNKTKVVRVESVRINNVEIDERRQNVKVFGRFVL 113 Query: 269 NWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATT-AGDYALRARVSN-NGSVSW 442 +W D +SW+ +WG S ++W P++V +N +T+ G + +N G + Sbjct: 114 SWNDTMVSWDKEQWGLSWLNFYWIQIWTPNIVQINGGSTSNPGQVTSKVLAANYTGQIYL 173 Query: 443 IKRLDISTPISMQLDNWPNDMQTCTFKFGSR 535 +TP Q +++PNDMQ +KF + Sbjct: 174 WSDFSFTTPFRFQYEDYPNDMQRVCYKFDDK 204 >UniRef50_Q2XWK5 Cluster: Nicotinic acetylcholine receptor subunit type H; n=1; Lymnaea stagnalis|Rep: Nicotinic acetylcholine receptor subunit type H - Lymnaea stagnalis (Great pond snail) Length = 450 Score = 66.1 bits (154), Expect = 1e-09 Identities = 48/175 (27%), Positives = 78/175 (44%), Gaps = 6/175 (3%) Frame = +2 Query: 122 SLMIDSLLATYDRE----SPPDSKIVVNLTLHLRHAN-IRESESTVRILADLQMNWIDKR 286 S ++ LL YDR P + V+ L L+ + E + ++ + W D R Sbjct: 25 SRLMRDLLTDYDRRVRPVQRPSDTVHVSFGLGLKALLFVDEKREYMETVSYMLTAWHDGR 84 Query: 287 LSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVSWIKRLDIS 463 L WN ++ G T + + LW PD+V + A + +G VSWI L + Sbjct: 85 LMWNMSQYAGIDTIKIPAVDLWTPDIVPYTSIDEDIHLMETMAVIYASGHVSWIPTLHLR 144 Query: 464 TPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDKRIYSMFESGAWDVTDLSS 628 +P S+ L +P D Q C+ KF S ++ D ++ + A+DV+D SS Sbjct: 145 SPCSVNLKYFPFDEQKCSIKFASYGYHGDHLNIT----YFGSTPEHAFDVSDYSS 195 >UniRef50_UPI0000E48B7E Cluster: PREDICTED: similar to neuronal nicotinic acetylcholine receptor alpha3 subunit; n=1; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to neuronal nicotinic acetylcholine receptor alpha3 subunit - Strongylocentrotus purpuratus Length = 525 Score = 65.3 bits (152), Expect = 2e-09 Identities = 50/203 (24%), Positives = 95/203 (46%), Gaps = 8/203 (3%) Frame = +2 Query: 35 MSTTYIILLPFLLTCAIASAAECENATSLSLMIDSLLATYDRESPPDSKIVVNLTLHLRH 214 + TT I ++ + A + AAE A +L+ + + ES P +VV L + Sbjct: 13 LHTTLIYIIMNITGTAASRAAELLYA-NLTEDYNIFIRPVKNESDP---VVVKFGLSISQ 68 Query: 215 A-NIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATT 388 I E + ++ W D L WN ++ G + + +E +WRPD++L N A Sbjct: 69 LIAIDEKNQVMTTSVWVKHEWQDHHLMWNPEDYEGITELHIPAENIWRPDILLYNNANGN 128 Query: 389 AG-DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDF- 562 + + A V G+V+W+ + ++ ++ +P D Q+C KFG H++ ++D Sbjct: 129 FDVQFLVNAIVKYTGTVTWLPPAIYKSSCTIDIEYFPFDEQSCKMKFGPWTHDTLKIDMA 188 Query: 563 ----VIDKRIYSMFESGAWDVTD 619 V+D+ Y + +G W++ + Sbjct: 189 SSNDVVDQEDY--WPNGEWEIVE 209 >UniRef50_Q7T2S3 Cluster: Nicotinic acetylcholine receptor alpha 4 subunit; n=2; Tetraodontidae|Rep: Nicotinic acetylcholine receptor alpha 4 subunit - Fugu rubripes (Japanese pufferfish) (Takifugu rubripes) Length = 622 Score = 65.3 bits (152), Expect = 2e-09 Identities = 46/179 (25%), Positives = 87/179 (48%), Gaps = 15/179 (8%) Frame = +2 Query: 128 MIDSLLATYDRESPPDSKIVVNLTLHL-----RHANIRESESTVRILADLQMNWIDKRLS 292 ++ L A Y++ S P + +H + ++ E + ++ W D +L Sbjct: 14 LLQDLFAHYNKLSRPVENTTDTVLVHFGLSIAQLIDVDEKNQMMTTNVWVKQEWNDYKLR 73 Query: 293 WNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNGSVSWIKRLD 457 WN E+ T + + SE +WRPD+VL N A GD+A+ +A++ +G + W+ Sbjct: 74 WNPEEYENVTSIRIPSEIIWRPDIVLYNNAD---GDFAVTHLTKAQLFYDGRIKWMPPAI 130 Query: 458 ISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFV-----IDKRIYSMFESGAWDVTD 619 + S+ + +P D Q+C KFGS ++ ++D + +D+ Y +ESG W + + Sbjct: 131 YKSSCSIDVTFFPFDQQSCKMKFGSWTYDRAKIDLISMASDVDQMDY--WESGEWVIVN 187 >UniRef50_Q9N4M3 Cluster: Acetylcholine receptor protein 6; n=1; Caenorhabditis elegans|Rep: Acetylcholine receptor protein 6 - Caenorhabditis elegans Length = 562 Score = 65.3 bits (152), Expect = 2e-09 Identities = 33/118 (27%), Positives = 59/118 (50%), Gaps = 2/118 (1%) Frame = +2 Query: 218 NIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLL-NAAATTA 391 ++ E + + + L +W+D RLSWN E+G T + E LW PD++L NA + Sbjct: 44 DVHEKDQVITLKGTLIHHWLDYRLSWNPDEFGNITLMHFPGEMLWLPDIILYNNAHGSPW 103 Query: 392 GDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFV 565 + VS G V+W + ++ ++ +P D+Q C KFGS + +++ + Sbjct: 104 VSETTQVHVSFEGRVTWQPPVVYDAFCNIDIEWYPYDLQICELKFGSWTYGGSQLNLI 161 >UniRef50_Q8JFN7 Cluster: Neuronal acetylcholine receptor subunit alpha-9-I precursor; n=8; Clupeocephala|Rep: Neuronal acetylcholine receptor subunit alpha-9-I precursor - Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri) Length = 572 Score = 65.3 bits (152), Expect = 2e-09 Identities = 44/180 (24%), Positives = 82/180 (45%), Gaps = 7/180 (3%) Frame = +2 Query: 50 IILLPFLLTCAIASAAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHANI 223 ++LL ++ +C I + + L+ D L+ Y P D+ +N+TL + + I Sbjct: 4 VVLLTWI-SCWIDVCTSAQGRYAQKLLND-LMENYSSALRPVEDTDKTLNVTLQITLSQI 61 Query: 224 RESESTVRILAD---LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTA 391 ++ + ++L ++ W D L W+ E+ G + S +WRPD+VL N A A Sbjct: 62 KDMDERNQVLTTYLWIRQTWFDAYLKWDKEEYDGLEVIRIPSNLVWRPDIVLYNKADEEA 121 Query: 392 -GDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVI 568 G + NG ++W + + + +P D Q C FGS +N +++D + Sbjct: 122 SGPADTNVVLRYNGEITWDMPAITKSSCVVDVSYFPFDWQWCNLTFGSWTYNGNQVDIAM 181 >UniRef50_UPI0000E47C59 Cluster: PREDICTED: similar to alpha-9 nicotinic acetylcholine receptor subunit precursor; n=1; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to alpha-9 nicotinic acetylcholine receptor subunit precursor - Strongylocentrotus purpuratus Length = 451 Score = 64.9 bits (151), Expect = 3e-09 Identities = 42/125 (33%), Positives = 64/125 (51%), Gaps = 5/125 (4%) Frame = +2 Query: 269 NWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYALRARV--SNNGSVS 439 NW D+ + W+ +G T L ++SE +W PDVVL N AA D+ V +N G V+ Sbjct: 42 NWKDEFMMWDPAVYGNITDLKIASELVWMPDVVLYNNAAKEYKDFMKDEIVVITNEGQVN 101 Query: 440 WIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD-FVIDKRIYSMFES-GAWDV 613 W IS+ S+ ++ +P D Q C KFG H E+ + S+F S G WD+ Sbjct: 102 WAAPKIISSYCSINVNTFPFDEQQCPMKFGPWQHEGKELRIWGGGSGDASVFNSDGQWDI 161 Query: 614 TDLSS 628 +++ Sbjct: 162 LAMTA 166 >UniRef50_Q9GP98 Cluster: Acetylcholine receptor protein 22; n=3; Caenorhabditis|Rep: Acetylcholine receptor protein 22 - Caenorhabditis elegans Length = 434 Score = 64.9 bits (151), Expect = 3e-09 Identities = 39/164 (23%), Positives = 78/164 (47%), Gaps = 7/164 (4%) Frame = +2 Query: 185 VVNLTLHLRHAN---IRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWR 352 V+N+T+ + N + E ++IL +W D L+W+ EW G ++ ++W Sbjct: 60 VLNVTVQPQIYNLVEVNEQNEQIKILLWFPQSWKDDYLTWDPKEWNGIERIIIPKSQIWI 119 Query: 353 PDVVLLNAAATT--AGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKF 526 PD + N T ++ R R V + K +D++ P+S+ ++P D+Q C +F Sbjct: 120 PDGYIFNTVEETEPLENHNARVRYDGRVEVDFNKLVDLTCPMSVL--SFPFDVQLCALQF 177 Query: 527 GSRMHNSDEMDF-VIDKRIYSMFESGAWDVTDLSSAVXSQDRGE 655 GS + + + F V+D + ++ WD+ ++ + G+ Sbjct: 178 GSWSYQAHAISFNVLDTFVPKKSKNSEWDIVSFNATKMTTKYGD 221 >UniRef50_Q66T35 Cluster: Nicotinic acetylcholine receptor subunit alpha 3; n=7; Coelomata|Rep: Nicotinic acetylcholine receptor subunit alpha 3 - Anopheles gambiae (African malaria mosquito) Length = 710 Score = 64.9 bits (151), Expect = 3e-09 Identities = 50/190 (26%), Positives = 84/190 (44%), Gaps = 10/190 (5%) Frame = +2 Query: 86 ASAAECENATSLSLMIDSLLATYDRESPPDSKIVVNLTLHLR-------HANIRESESTV 244 A + C + D LL+ Y++ P + LT+ ++ N++ T Sbjct: 13 AVVSVCGGNPDAKRLYDDLLSNYNKLVRPVVNVTDALTVKIKLKLSQLIDVNLKNQIMTT 72 Query: 245 RILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAA-ATTAGDYALRARV 418 + ++ W D +L W E+G L V S+ +WRPD+VL N A A +A + Sbjct: 73 NLW--VEQTWYDYKLKWEPKEYGGVEMLHVPSDHIWRPDIVLYNNADGNFEVTLATKATL 130 Query: 419 SNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDKRIYSMFES 598 + G V W + + ++ +P D QTC KFGS ++ ++D + I M E+ Sbjct: 131 NYTGRVEWRPPAIYKSSCEIDVEYFPFDEQTCVMKFGSWTYDGFQVDL---RHIDEMNET 187 Query: 599 GAWDV-TDLS 625 +V DLS Sbjct: 188 NVVEVGVDLS 197 >UniRef50_Q66T21 Cluster: Nicotinic acetylcholine receptor subunit alpha 9; n=4; Culicidae|Rep: Nicotinic acetylcholine receptor subunit alpha 9 - Anopheles gambiae (African malaria mosquito) Length = 406 Score = 64.9 bits (151), Expect = 3e-09 Identities = 44/170 (25%), Positives = 74/170 (43%), Gaps = 8/170 (4%) Frame = +2 Query: 140 LLATYD---RESPPDSKIVVNLTLHLRHANIRESESTVRILADLQMNWIDKRLSWNAGEW 310 LL YD R S + V + + H I E +ST+ + ++ +W D +L+WN + Sbjct: 46 LLKGYDPSIRPSQHYNVTTVETGITITHVEINEIKSTLSVYGWMKFSWNDPKLTWNPASY 105 Query: 311 G-CSTWLVSSERLWRPDVVLL-NAAATTAGDYA-LRARVSNNGSVSWIKRLDISTPISMQ 481 G + +WRPDVVL NA + Y V + G V W+ + + Sbjct: 106 GNLNVVRWDPTIVWRPDVVLYNNAGGSDQHHYGDTNVLVYSEGKVLWVPPTEYHAFCELN 165 Query: 482 LDNWPNDMQTCTFKFGSRMHNSDEMDFVI--DKRIYSMFESGAWDVTDLS 625 + WP D Q C K GS + ++ I + +I ++ + W + +S Sbjct: 166 MRLWPFDYQKCIVKIGSWTFDGYMLNLTIGSEPQIETLVSNSEWKIAKIS 215 >UniRef50_O16926 Cluster: Acetylcholine receptor protein 15; n=2; Caenorhabditis|Rep: Acetylcholine receptor protein 15 - Caenorhabditis elegans Length = 479 Score = 64.9 bits (151), Expect = 3e-09 Identities = 52/197 (26%), Positives = 91/197 (46%), Gaps = 8/197 (4%) Frame = +2 Query: 53 ILLPFLLTCAIASAAECENATSLSLMIDSLLATYDRESPP--DSK--IVVNLTLHLRHA- 217 +LLP LL + + + + +I+ L++ Y RE P DS +VV+L + L+ Sbjct: 1 MLLPILLHFLLL-ITQLNGSPAEVRLINDLMSGYVREERPTLDSSKPVVVSLGVFLQQII 59 Query: 218 NIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERLWRPDVVLLNAAATTA- 391 N+ E E + + A L+ W D+ L W + T L + LW PD++L N+ + Sbjct: 60 NLSEKEEQLEVNAWLKFQWRDENLRWEPTAYENVTDLRHPPDALWTPDILLYNSVDSEFD 119 Query: 392 GDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVID 571 Y + + G+++W+ + + +P D Q C FKFGS + D++ Sbjct: 120 SSYKVNLVNYHTGNINWMPPGIFKVSCKLDIYWFPFDEQVCYFKFGSWTYTRDKIQLEKG 179 Query: 572 KRIYSMF-ESGAWDVTD 619 +S F +G W + D Sbjct: 180 DFDFSEFIPNGEWIIID 196 >UniRef50_P11230 Cluster: Acetylcholine receptor subunit beta precursor; n=30; Gnathostomata|Rep: Acetylcholine receptor subunit beta precursor - Homo sapiens (Human) Length = 501 Score = 64.9 bits (151), Expect = 3e-09 Identities = 47/137 (34%), Positives = 70/137 (51%), Gaps = 4/137 (2%) Frame = +2 Query: 158 RESPPDSKIVVNLTL-HLRHANIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLV 331 RE ++ V L L L N ++ E + ++ DL+ W D RLSW+ E G + + Sbjct: 46 REVGDRVRVSVGLILAQLISLNEKDEEMSTKVYLDLE--WTDYRLSWDPAEHDGIDSLRI 103 Query: 332 SSERLWRPDVVLLNAAATTAGDYAL--RARVSNNGSVSWIKRLDISTPISMQLDNWPNDM 505 ++E +W PDVVLLN D AL VS++GSV W + S+Q+ +P D Sbjct: 104 TAESVWLPDVVLLNNNDGNF-DVALDISVVVSSDGSVRWQPPGIYRSSCSIQVTYFPFDW 162 Query: 506 QTCTFKFGSRMHNSDEM 556 Q CT F S ++S E+ Sbjct: 163 QNCTMVFSSYSYDSSEV 179 >UniRef50_P48180 Cluster: Acetylcholine receptor subunit alpha-type acr-16 precursor; n=3; Caenorhabditis|Rep: Acetylcholine receptor subunit alpha-type acr-16 precursor - Caenorhabditis elegans Length = 498 Score = 64.9 bits (151), Expect = 3e-09 Identities = 47/171 (27%), Positives = 78/171 (45%), Gaps = 7/171 (4%) Frame = +2 Query: 68 LLTCAIASAAECENATSLSLMIDSLLATYDRESPPDSKIVVNLTLHLRHA-----NIRES 232 L++CAI +A + L D L+ Y+ P + +T+HL+ A ++ E Sbjct: 7 LISCAILAAPTLGSLQERRLYED-LMRNYNNLERPVANHSEPVTVHLKVALQQIIDVDEK 65 Query: 233 ESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGD-YAL 406 V + A L W D L W+ E+G T + + ++W+PDV+L N+ T Y Sbjct: 66 NQVVYVNAWLDYTWNDYNLVWDKAEYGNITDVRFPAGKIWKPDVLLYNSVDTNFDSTYQT 125 Query: 407 RARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 559 V + G V W+ + + +P D Q C FKFGS ++ ++D Sbjct: 126 NMIVYSTGLVHWVPPGIFKISCKIDIQWFPFDEQKCFFKFGSWTYDGYKLD 176 >UniRef50_Q8WSF7 Cluster: GABA A receptor alpha subunit; n=1; Aplysia californica|Rep: GABA A receptor alpha subunit - Aplysia californica (California sea hare) Length = 448 Score = 64.5 bits (150), Expect = 3e-09 Identities = 42/154 (27%), Positives = 71/154 (46%), Gaps = 7/154 (4%) Frame = +2 Query: 116 SLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESESTVRILADLQMNWIDK 283 ++S ++DSLL YD+ P + VN + LR I E + + W+D Sbjct: 33 NISQVLDSLLEGYDKRLRPGFGGEALTVNADISLRSMGPISELNMIYTLDCYFRQRWMDH 92 Query: 284 RLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAAT---TAGDYALRARVSNNGSVSWIKRL 454 RL+ N + + ER+W PD V N + + R++ NG+V + +RL Sbjct: 93 RLAMNVSLENLTLGIKILERIWHPDTVFYNGQKSYLHAITSHNRFLRIAANGTVLFSQRL 152 Query: 455 DISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEM 556 I M +N+P D+Q C GS +++D++ Sbjct: 153 TIQATCRMHPENFPMDIQHCPLLIGSFAYSTDDV 186 >UniRef50_A0EIZ7 Cluster: Nicotinic acetylcholine receptor alpha9 subunit; n=1; Apis mellifera|Rep: Nicotinic acetylcholine receptor alpha9 subunit - Apis mellifera (Honeybee) Length = 431 Score = 64.5 bits (150), Expect = 3e-09 Identities = 43/170 (25%), Positives = 79/170 (46%), Gaps = 8/170 (4%) Frame = +2 Query: 104 ENATSLSLMIDSLLATYDRESPPDS--KIVVNLTLHL--RHANIRESESTVRILADLQMN 271 ++ T+L + L YD P S +I N+T+ L + + S + + + + + Sbjct: 39 DHPTTLLKLKRYLFCEYDPNVRPISSHQIANNVTMQLLPKLMEFDDWTSVMELHSWMTLM 98 Query: 272 WIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATT---AGDYALRARVSNNGSVS 439 W D LSW ++ G + V S+ +W PD+ + N+ T G V ++GSVS Sbjct: 99 WTDSHLSWKPSDFDGINYIYVKSDDIWVPDISVYNSGDMTFDQTGIPPTTCLVFSSGSVS 158 Query: 440 WIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDKRIYSM 589 + + + +WP D C FGS +H+ +E++ +DK+ + M Sbjct: 159 CVPSVKHVAKCATDFSSWPYDTHRCRINFGSWVHSGEEVNIFLDKKGFHM 208 >UniRef50_Q7Z6B2 Cluster: 5-hydroxytryptamine serotonin receptor 3E; n=30; Theria|Rep: 5-hydroxytryptamine serotonin receptor 3E - Homo sapiens (Human) Length = 471 Score = 64.5 bits (150), Expect = 3e-09 Identities = 36/140 (25%), Positives = 67/140 (47%), Gaps = 9/140 (6%) Frame = +2 Query: 260 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 436 L+M W + +SWN E G + ++++ LW PD+ ++ L A VSN G + Sbjct: 106 LEMVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEGRI 165 Query: 437 SWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDKRIYSMFES------ 598 + K + + + ++ + +P D Q CT F S ++ D M ++K ++ + ++ Sbjct: 166 RYKKPMKVDSICNLDIFYFPFDQQNCTLTFSSFLYTVDSMLLDMEKEVWEITDASRNILQ 225 Query: 599 --GAWDVTDLSSAVXSQDRG 652 G W++ LS A RG Sbjct: 226 THGEWELLGLSKATAKLSRG 245 >UniRef50_P54245 Cluster: Uncharacterized acetylcholine receptor-like protein F18G5.4 precursor; n=2; Caenorhabditis|Rep: Uncharacterized acetylcholine receptor-like protein F18G5.4 precursor - Caenorhabditis elegans Length = 615 Score = 64.5 bits (150), Expect = 3e-09 Identities = 36/129 (27%), Positives = 67/129 (51%), Gaps = 6/129 (4%) Frame = +2 Query: 260 LQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLLNAAATT--AGDYALRARVSNNG 430 L +NW+D RLSWN W + R+W+PD++L+N A A + V+++G Sbjct: 165 LNINWMDPRLSWNESLWSEIKAIYIPHARIWKPDIILVNNAIREYYASLVSTDVMVTSDG 224 Query: 431 SVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVI--DK-RIYSMFESG 601 +V+W+ + +++ +P D Q C KF S H+ E++ + DK + S + Sbjct: 225 NVTWLFSALFRSSCPIRVRYYPFDDQQCDLKFASWSHDITEINLGLNTDKGDLSSYMNNS 284 Query: 602 AWDVTDLSS 628 +D+ D+++ Sbjct: 285 EFDLVDMTA 293 >UniRef50_P07510 Cluster: Acetylcholine receptor subunit gamma precursor; n=31; Gnathostomata|Rep: Acetylcholine receptor subunit gamma precursor - Homo sapiens (Human) Length = 517 Score = 64.5 bits (150), Expect = 3e-09 Identities = 47/179 (26%), Positives = 81/179 (45%), Gaps = 8/179 (4%) Frame = +2 Query: 62 PFLLTCAIASAAECENATSLSLMIDSLLATYDRESPPDSKI--VVNLTLHLRHANI---R 226 P LL +A + ++ L+ YD P + VVN++L L N+ Sbjct: 7 PLLLLLLLAVCLGAQGRNQEERLLADLMQNYDPNLRPAERDSDVVNVSLKLTLTNLISLN 66 Query: 227 ESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYA 403 E E + ++M W D RL W+ ++ G V S +WRPD+VL N + A Sbjct: 67 EREEALTTNVWIEMQWCDYRLRWDPRDYEGLWVLRVPSTMVWRPDIVLENNVDGVF-EVA 125 Query: 404 LRARV--SNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDK 574 L V S +G + W+ + S+ + +P D Q C+ F S+ ++++E+D + + Sbjct: 126 LYCNVLVSPDGCIYWLPPAIFRSACSISVTYFPFDWQNCSLIFQSQTYSTNEIDLQLSQ 184 >UniRef50_UPI00015B4DDF Cluster: PREDICTED: similar to neurotransmitter gated ion channel; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to neurotransmitter gated ion channel - Nasonia vitripennis Length = 461 Score = 63.7 bits (148), Expect = 6e-09 Identities = 43/168 (25%), Positives = 75/168 (44%), Gaps = 5/168 (2%) Frame = +2 Query: 71 LTCAIASAAECENATSLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHANIRESEST 241 LT + +S N T + LLA YD+ + P + V++ L+++ + + + Sbjct: 26 LTLSKSSNYPAWNETWTDRLKQHLLAKYDKFARPAQHWNTTTVSVKLNVQTVEVDDMTNV 85 Query: 242 VRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALR-AR 415 + + M W D +L+WN+ E+ G + + +W PD+ LLN+AA Y R Sbjct: 86 MAANVWVVMTWNDDKLTWNSSEYSGLKQVNLGAHEIWLPDIYLLNSAAHGMEYYGDRHCV 145 Query: 416 VSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 559 VS G V W+ + WP +M TC S ++ ++D Sbjct: 146 VSEQGVVLWVTPTIFHGYCHLDFTFWPFEMNTCRLSLSSWTYDGTQVD 193 >UniRef50_UPI0000E49402 Cluster: PREDICTED: similar to alpha 10 subunit of nicotinic acetylcholine receptor; n=1; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to alpha 10 subunit of nicotinic acetylcholine receptor - Strongylocentrotus purpuratus Length = 473 Score = 63.7 bits (148), Expect = 6e-09 Identities = 36/122 (29%), Positives = 60/122 (49%), Gaps = 5/122 (4%) Frame = +2 Query: 272 WIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLL-NAAATTAGDYALRARVSNNGSVSWI 445 W D L WN ++G +T L V E +WRPD+VL NA ++ G A +S++G V W Sbjct: 80 WTDSNLKWNPADYGDTTVLIVPIETIWRPDIVLFTNADSSFNGMMMTSASISHDGIVRWN 139 Query: 446 KRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDF---VIDKRIYSMFESGAWDVT 616 + + + +P D Q C+ KFGS ++ ++D I + ++G W + Sbjct: 140 APAIYQSTCKIDITYFPFDEQHCSLKFGSWAYHGFQIDLKNRTTSGDISAYIDNGEWTLV 199 Query: 617 DL 622 + Sbjct: 200 GM 201 >UniRef50_Q4SXG5 Cluster: Chromosome undetermined SCAF12416, whole genome shotgun sequence; n=3; Tetraodontidae|Rep: Chromosome undetermined SCAF12416, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 643 Score = 63.7 bits (148), Expect = 6e-09 Identities = 48/179 (26%), Positives = 90/179 (50%), Gaps = 9/179 (5%) Frame = +2 Query: 50 IILLPFLLTCAIAS---AAECENATSLSLMIDSLLATYDRESPPDSKIVVNLTLHLRH-- 214 ++LL +C + S A E E+A +L + L SP + ++VV + + L Sbjct: 3 LLLLLSCCSCTLISLGGAFEVESALLKNLFSNYTLKVRPAVSP-EQRVVVRVGMILSSFV 61 Query: 215 -ANIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATT 388 N++ E + ++ +L+ W D RLSW+ ++ G + S ++W PD+VL+N Sbjct: 62 GLNMKNEEMSTIVVMNLE--WTDYRLSWSPKDYDGIEVLRIPSGKIWLPDIVLINNNDGV 119 Query: 389 AGDYALRARVS--NNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 559 + AL+ V +NG V+W + ++++ +P D Q C+ +F S ++S E+D Sbjct: 120 F-EVALQVHVQVYSNGRVTWTPPALYCSSCGVKVEYFPFDWQNCSMQFRSYTYDSTEID 177 >UniRef50_Q0GQR6 Cluster: GABA-gated ion channel; n=2; Apis mellifera|Rep: GABA-gated ion channel - Apis mellifera (Honeybee) Length = 463 Score = 63.7 bits (148), Expect = 6e-09 Identities = 41/149 (27%), Positives = 70/149 (46%), Gaps = 7/149 (4%) Frame = +2 Query: 107 NATSLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESESTVRILADLQMNW 274 N +++S ++D+LL YD PD V + + +R I E + T + + +W Sbjct: 2 NHSNISELLDNLLRGYDNSVRPDFGGPPATVEVDIMVRSMGPISEVDMTYSMDCYFRQSW 61 Query: 275 IDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAAT---TAGDYALRARVSNNGSVSWI 445 +D+RL++ G+ + + R+W+PD N + T R+ +G V + Sbjct: 62 VDRRLAFQGGKETLALSISMLARIWKPDTYFYNGKHSYLHTITSPNKFVRLYQDGRVLYS 121 Query: 446 KRLDISTPISMQLDNWPNDMQTCTFKFGS 532 RL I M L+N+P D Q C +FGS Sbjct: 122 SRLTIKAGCPMNLENFPMDTQRCPLQFGS 150 >UniRef50_A7UFK6 Cluster: Nicotinic acetylcholine receptor alpha subunit; n=2; Ascaris suum|Rep: Nicotinic acetylcholine receptor alpha subunit - Ascaris suum (Pig roundworm) (Ascaris lumbricoides) Length = 513 Score = 63.7 bits (148), Expect = 6e-09 Identities = 46/171 (26%), Positives = 77/171 (45%), Gaps = 7/171 (4%) Frame = +2 Query: 59 LPFLLTCAIASAAECENATSLSLMIDSLLATYDRES----PPDSKIVVNLTLHLRHA-NI 223 L +L+ C + E+A L D L+ Y++ P + + L L L ++ Sbjct: 8 LLWLVVCGTSLTVGNEDAKRL---YDDLMVNYNKHRRPAMSPHEPVTIKLKLRLSQIIDV 64 Query: 224 RESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAG-D 397 E + + L+ WIDK+LSW+ + G S V E +W PD+VL N A + Sbjct: 65 HEIDQIMTYSVWLKQVWIDKKLSWDPKNYGGVSVLYVPYEMIWVPDIVLYNNADSNYNIT 124 Query: 398 YALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSD 550 + +A + +G V+W + + + +P D Q C KFGS ++ D Sbjct: 125 ISTKATLHYSGEVTWEPPAIFKSMCQIDVRWFPFDEQKCHLKFGSWTYSED 175 >UniRef50_A7RNI2 Cluster: Predicted protein; n=3; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 485 Score = 63.7 bits (148), Expect = 6e-09 Identities = 49/206 (23%), Positives = 93/206 (45%), Gaps = 13/206 (6%) Frame = +2 Query: 35 MSTTYIILLPFLLTCAIASAAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHL 208 M+ + LLPFL S E+ +++ L Y++E+ P + + + + Sbjct: 1 MAPLLLSLLPFLFVFPSLSVDHTEDVEHR--LLNDLFKDYNKEARPVLNKSEAIEVQFDM 58 Query: 209 RHANIRESESTVRILAD---LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN- 373 +A + S +IL + W++ L+W+ +G T + V+ +W+PD+VL + Sbjct: 59 AYAQLINLNSKDQILQSKVWFRQRWVNPFLTWDPKMYGGLTSINVNPNMIWKPDIVLYHN 118 Query: 374 -AAATTAGDYAL--RARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHN 544 T Y RA + +NG W +I + ++ + +P D Q C KFGS ++ Sbjct: 119 IGFGETGAIYKFDTRATIMHNGYTEWFAPTEIHSICAIDITYFPFDEQFCKMKFGSWSYS 178 Query: 545 SDEMDFVI--DKRIYSMF-ESGAWDV 613 +++ D S + +SG WD+ Sbjct: 179 GRQLNLTSKGDSADLSKYTKSGEWDL 204 >UniRef50_UPI00015B5C4C Cluster: PREDICTED: similar to GABA-gated ion channel; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to GABA-gated ion channel - Nasonia vitripennis Length = 442 Score = 63.3 bits (147), Expect = 8e-09 Identities = 41/152 (26%), Positives = 72/152 (47%), Gaps = 7/152 (4%) Frame = +2 Query: 98 ECENATSLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESESTVRILADLQ 265 + N ++S ++D+LL YD P+ VV + + +R I E + T + + Sbjct: 43 QSNNHGNISELLDNLLRGYDNSVRPNFGGPPAVVEVDIMVRSMGPISEVDMTYSMDCYFR 102 Query: 266 MNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAAT---TAGDYALRARVSNNGSV 436 +W+D+RL++ +G+ + + R+W+PD N + T R+ +G V Sbjct: 103 QSWVDRRLAFQSGKETLALSISMLARIWKPDTYFYNGKQSYLHTITSPNKFVRLYQDGRV 162 Query: 437 SWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 532 + RL I M L+++P D Q C KFGS Sbjct: 163 LYSSRLTIKAACPMNLEDFPMDTQRCPLKFGS 194 >UniRef50_Q24352 Cluster: Gamma-aminobutyric acid receptor alpha-like precursor (GABA(A) receptor alpha-like and glycine receptor-like subunit of Drosophila); n=3; Diptera|Rep: Gamma-aminobutyric acid receptor alpha-like precursor (GABA(A) receptor alpha-like and glycine receptor-like subunit of Drosophila) - Drosophila melanogaster (Fruit fly) Length = 686 Score = 63.3 bits (147), Expect = 8e-09 Identities = 41/152 (26%), Positives = 69/152 (45%), Gaps = 7/152 (4%) Frame = +2 Query: 98 ECENATSLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESESTVRILADLQ 265 + N ++S ++D+LL YD PD + + + +R I E + T + + Sbjct: 102 QSNNHANISELLDNLLRGYDNSIRPDFGGPPATIEVDIMVRSMGPISEVDMTYSMDCYFR 161 Query: 266 MNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAAT---TAGDYALRARVSNNGSV 436 +W+DKRL++ + + + R+W+PD N + T R+ NG V Sbjct: 162 QSWVDKRLAFEGAQDTLALSVSMLARIWKPDTYFYNGKQSYLHTITTPNKFVRIYQNGRV 221 Query: 437 SWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 532 + RL I M L ++P D+Q C KFGS Sbjct: 222 LYSSRLTIKAGCPMNLADFPMDIQKCPLKFGS 253 >UniRef50_Q04844 Cluster: Acetylcholine receptor subunit epsilon precursor; n=35; Euteleostomi|Rep: Acetylcholine receptor subunit epsilon precursor - Homo sapiens (Human) Length = 493 Score = 63.3 bits (147), Expect = 8e-09 Identities = 36/134 (26%), Positives = 71/134 (52%), Gaps = 3/134 (2%) Frame = +2 Query: 170 PDSKIVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEWG-CSTWLVSSER 343 P+ + ++L + L + ++ E E T+ + ++W D RL+++ ++G T V SE Sbjct: 45 PEDTVTISLKVTLTNLISLNEKEETLTTSVWIGIDWQDYRLNYSKDDFGGIETLRVPSEL 104 Query: 344 LWRPDVVLLNAAATTAG-DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTF 520 +W P++VL N G Y V GSV+W+ + ++++ +P D Q C+ Sbjct: 105 VWLPEIVLENNIDGQFGVAYDANVLVYEGGSVTWLPPAIYRSVCAVEVTYFPFDWQNCSL 164 Query: 521 KFGSRMHNSDEMDF 562 F S+ +N++E++F Sbjct: 165 IFRSQTYNAEEVEF 178 >UniRef50_Q2XWK3 Cluster: Nicotinic acetylcholine receptor subunit type K; n=1; Lymnaea stagnalis|Rep: Nicotinic acetylcholine receptor subunit type K - Lymnaea stagnalis (Great pond snail) Length = 501 Score = 62.9 bits (146), Expect = 1e-08 Identities = 46/173 (26%), Positives = 79/173 (45%), Gaps = 10/173 (5%) Frame = +2 Query: 128 MIDSLLATYDRESP---P----DSKIVVNLTLHL-RHANIRESESTVRILADLQMNWIDK 283 +I +LLA Y R P + I +N + L + ++ E + + + W D Sbjct: 31 LIKNLLARYKRRGTYARPVKEYNDSITINFNMQLIQIMDLDEKNQVLTLNVWDRYIWHDL 90 Query: 284 RLSWNAGEWG-CSTWLVSSERLWRPDVVLLNAAATTAGDYA-LRARVSNNGSVSWIKRLD 457 L+WN + G V S ++W PD+ L N A + R V +NG V W+ + Sbjct: 91 HLTWNETKHGGVKNIRVPSNKIWIPDLKLYNYADERLAERRDARCVVESNGKVLWMPQAI 150 Query: 458 ISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDKRIYSMFESGAWDVT 616 + + + +P D+Q CT KFGS HN + +D ++ E+G+ D++ Sbjct: 151 YKSSCEIDVATFPFDIQNCTLKFGSWTHNGNLIDLMVLSMDGETGENGSIDMS 203 >UniRef50_UPI00015B5C6B Cluster: PREDICTED: similar to nicotinic acetylcholine receptor alpha9 subunit; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to nicotinic acetylcholine receptor alpha9 subunit - Nasonia vitripennis Length = 304 Score = 62.5 bits (145), Expect = 1e-08 Identities = 38/132 (28%), Positives = 65/132 (49%), Gaps = 6/132 (4%) Frame = +2 Query: 266 MNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYAL---RARVSNNGS 433 MNW D L+WN ++ G T V S+ LW PD+ + N + G + +S++G Sbjct: 95 MNWTDPHLTWNPEDFEGLDTIQVPSDSLWTPDIAVHNTHDASKGKPGIAKTNCGLSHDGH 154 Query: 434 VSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD-FVIDKRIYSMFESG-AW 607 V+ + + ST ++P D+Q CT S +++DE+ ++ K + S G W Sbjct: 155 VTCVPAVKYSTNCLPDFTDYPYDLQVCTIDLASWAYSTDEIQLLMLRKPVTSDLSPGQEW 214 Query: 608 DVTDLSSAVXSQ 643 DV +S V ++ Sbjct: 215 DVLYSNSYVLNE 226 >UniRef50_A7RLM4 Cluster: Predicted protein; n=2; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 300 Score = 62.5 bits (145), Expect = 1e-08 Identities = 40/156 (25%), Positives = 75/156 (48%), Gaps = 8/156 (5%) Frame = +2 Query: 152 YDRESPPDSK--IVVNLTLHLRHANIRESESTVRIL---ADLQMNWIDKRLSWNAGEW-G 313 YD + P + + +N+T + I E ++L +++ +W+D L+WN ++ G Sbjct: 3 YDPQVRPSDRADMPINITFGISLNEIYELTDRTQLLITKVEIRESWVDTSLAWNKSDFEG 62 Query: 314 CSTWLVSSERLWRPDVVLLNAAATTAGDYALR--ARVSNNGSVSWIKRLDISTPISMQLD 487 + ++ E +WRPD+VL N A GD R A V+++G VS + T + Sbjct: 63 LAKIVLRPESIWRPDIVLYNNAGEDFGDGQTRTNAVVTSDGLVSMTIPSILKTSCKIDAT 122 Query: 488 NWPNDMQTCTFKFGSRMHNSDEMDFVIDKRIYSMFE 595 +P D Q+C FGS ++ + + ++ + E Sbjct: 123 RYPFDKQSCPMIFGSWTYDGNLLSIKMESHSADLSE 158 >UniRef50_A2TM48 Cluster: Nicotinic acetylcholine receptor alpha 1 subunit; n=3; Aphidinae|Rep: Nicotinic acetylcholine receptor alpha 1 subunit - Sitobion avenae (English grain aphid) Length = 496 Score = 62.5 bits (145), Expect = 1e-08 Identities = 49/162 (30%), Positives = 74/162 (45%), Gaps = 12/162 (7%) Frame = +2 Query: 83 IASAAECENATSLSLMIDSLLATYDRESPPDSK----IVVNLTLHLRHA---NIRESEST 241 + SA C T + D LL+ Y+R P S ++V L L L N+++ T Sbjct: 12 LLSAVGCLCNTDAKRLYDDLLSNYNRLIRPVSNNTDTVLVKLGLRLSQLIELNLKDQILT 71 Query: 242 VRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYAL---- 406 + L+ W D + W E+G L V SE +W PD+VL N A G+Y + Sbjct: 72 TNVW--LEHEWADHKFIWEPLEYGGVKELYVPSEHIWLPDIVLYNNAD---GEYVVTTMT 126 Query: 407 RARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 532 +A + ++G V W + + + +P D QTC KFGS Sbjct: 127 KAVLHHSGKVMWTPPAIFKSSCEIDVRYFPFDQQTCFMKFGS 168 >UniRef50_Q4S866 Cluster: Chromosome 5 SCAF14709, whole genome shotgun sequence; n=1; Tetraodon nigroviridis|Rep: Chromosome 5 SCAF14709, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 215 Score = 62.1 bits (144), Expect = 2e-08 Identities = 28/99 (28%), Positives = 55/99 (55%), Gaps = 1/99 (1%) Frame = +2 Query: 260 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 436 + + W D +L W+ E+ G + V S+R+WRPDVVL + + +A V ++G++ Sbjct: 45 VDVEWTDMKLRWSPEEYVGITIIRVPSDRIWRPDVVLYDNSDGRFEGTVTKAVVKHDGTI 104 Query: 437 SWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDE 553 +W + + ++ + +P D+Q C+ KFGS ++ + Sbjct: 105 TWTAPANYKSACTIDVTFFPFDLQNCSMKFGSWTYDGSQ 143 >UniRef50_Q2XWL0 Cluster: Nicotinic acetylcholine receptor subunit type C; n=1; Lymnaea stagnalis|Rep: Nicotinic acetylcholine receptor subunit type C - Lymnaea stagnalis (Great pond snail) Length = 506 Score = 62.1 bits (144), Expect = 2e-08 Identities = 40/136 (29%), Positives = 66/136 (48%), Gaps = 6/136 (4%) Frame = +2 Query: 170 PDSKIVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSER 343 P K+ V L L L ++ E + I L+ W D RL W E+G L + S++ Sbjct: 54 PMKKLTVKLGLRLSQVLSVDERNQILTISVWLRQEWYDFRLKWEPSEYGGVNVLNIPSDQ 113 Query: 344 LWRPDVVLLNAAATTAGDYAL----RARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQT 511 LW+PD+VL N A GD+ + +A V++ G + W + + ++ +P D+Q Sbjct: 114 LWKPDLVLYNNA---DGDFQITLKTKAIVNHTGRIVWEPPAIYKSYCPIDVEYFPFDIQE 170 Query: 512 CTFKFGSRMHNSDEMD 559 C K S ++ E+D Sbjct: 171 CFLKISSWTYHGHELD 186 >UniRef50_A7S622 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 299 Score = 62.1 bits (144), Expect = 2e-08 Identities = 44/177 (24%), Positives = 81/177 (45%), Gaps = 15/177 (8%) Frame = +2 Query: 128 MIDSLLATYDRESPP----DSKIVVNLTLHLRH-ANIRESESTVRILADLQMNWIDKRLS 292 ++ L Y + + P D+ +V L+ +++++E ++I+ M W + L+ Sbjct: 4 LLRDLFQNYSKYARPSIESDAPAIVTFRAKLKQIVDLKDNEQLLKIILYNYMQWENPILT 63 Query: 293 WNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGD----YALRARVSNNGSVSWIKRLD 457 W+ ++G + V+ E +W PD+V+ N+A G Y + NG+ W+ Sbjct: 64 WDPRDYGGVQEINVAPEEVWVPDIVIYNSAEDVLGGLTHKYKTDVVIQANGTNIWLAPAM 123 Query: 458 ISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVI-----DKRIYSMFESGAWDV 613 T + + +P D Q C KFGS H+S +D +K IY+ E G W + Sbjct: 124 FLTTCQLDVRYFPFDEQKCLLKFGSWTHDSSRLDMRTQTNGSNKDIYT--EHGEWQL 178 >UniRef50_Q23022 Cluster: Acetylcholine receptor subunit alpha-type unc-38 precursor; n=9; Chromadorea|Rep: Acetylcholine receptor subunit alpha-type unc-38 precursor - Caenorhabditis elegans Length = 511 Score = 62.1 bits (144), Expect = 2e-08 Identities = 44/170 (25%), Positives = 76/170 (44%), Gaps = 7/170 (4%) Frame = +2 Query: 44 TYIILLPFLLTCAIASAAECENATSLSLMIDSLLATYDRE----SPPDSKIVVNLTLHLR 211 ++ + L LL C I+ E + D L+ Y+R + P+ + + L L L Sbjct: 3 SFWLFLLLLLFC-ISFIKLTEGNEDAKRLYDDLMVNYNRHRRPSTSPNKPLTIKLKLRLS 61 Query: 212 HA-NIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAAT 385 ++ E + + L+ WID++LSW+ + G + V E +W PD+VL N A + Sbjct: 62 QIIDVHEIDQIMTCSVWLKQTWIDRKLSWDPVNYGGVNVLYVPYEMIWVPDIVLYNNADS 121 Query: 386 TAG-DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 532 + +A + G V+W + + + +P D Q C KFGS Sbjct: 122 NYNITISTKATLHYTGEVTWEPPAIFKSMCQIDVRWFPFDEQQCHLKFGS 171 >UniRef50_Q65XS8 Cluster: Acetylcholine receptor protein 25; n=2; Caenorhabditis elegans|Rep: Acetylcholine receptor protein 25 - Caenorhabditis elegans Length = 544 Score = 61.3 bits (142), Expect = 3e-08 Identities = 42/148 (28%), Positives = 71/148 (47%), Gaps = 6/148 (4%) Frame = +2 Query: 182 IVVNLTLHLRH-ANIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRP 355 ++V + L L+ ++ E V + A L+ +W+D L W ++G T L +LW P Sbjct: 51 VMVKMGLVLQQIVDVDEKNQVVDVNAWLKFSWVDYSLKWKPEDYGGVTDLRFRKGQLWTP 110 Query: 356 DVVLLNAAATTAGD-YALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 532 DV++ N+A YA V NG V+W+ +Q+ +P D+Q C KFGS Sbjct: 111 DVLMYNSADPQFDSRYASNLLVYPNGLVNWMPPGLYRLSCKIQVVWFPFDVQECFLKFGS 170 Query: 533 RMHNSDEMDFVIDKR---IYSMFESGAW 607 + +++ ID I + ++G W Sbjct: 171 WTFDGTKLNLEIDDNGFDISNYMQNGEW 198 >UniRef50_Q9UGM1 Cluster: Neuronal acetylcholine receptor subunit alpha-9 precursor; n=30; Euteleostomi|Rep: Neuronal acetylcholine receptor subunit alpha-9 precursor - Homo sapiens (Human) Length = 479 Score = 60.5 bits (140), Expect = 5e-08 Identities = 45/184 (24%), Positives = 84/184 (45%), Gaps = 10/184 (5%) Frame = +2 Query: 92 AAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHANIRESESTVRILAD-- 259 AAE + + + L Y P D+ V+N+TL + + I++ + +IL Sbjct: 22 AAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQITLSQIKDMDERNQILTAYL 81 Query: 260 -LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGD-YALRARVSNNG 430 ++ W D L+W+ ++ G + + S+ +WRPD+VL N A + + + +G Sbjct: 82 WIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKADDESSEPVNTNVVLRYDG 141 Query: 431 SVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDF--VIDKRIYSMF-ESG 601 ++W + + + +P D Q C FGS +N +++D +D S F E Sbjct: 142 LITWDAPAITKSSCVVDVTYFPFDNQQCNLTFGSWTYNGNQVDIFNALDSGDLSDFIEDV 201 Query: 602 AWDV 613 W+V Sbjct: 202 EWEV 205 >UniRef50_Q9U298 Cluster: Neuronal acetylcholine receptor subunit eat-2 precursor; n=1; Caenorhabditis elegans|Rep: Neuronal acetylcholine receptor subunit eat-2 precursor - Caenorhabditis elegans Length = 474 Score = 60.5 bits (140), Expect = 5e-08 Identities = 44/155 (28%), Positives = 73/155 (47%), Gaps = 7/155 (4%) Frame = +2 Query: 128 MIDSLLATYDRESPP--DSKIVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLS 292 ++ L YD P D + VN+ L L + ++ E + ++ Q W D +L Sbjct: 28 LLKDLREGYDPVERPVADHRKPVNVKLRLILQQLVDVDERNQVITLVVWNQYTWNDYKLR 87 Query: 293 WNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTA-GDYALRARVSNNGSVSWIKRLDIST 466 W+ E+G T L + LW+PD++L N+A + + VS+NG V + +S Sbjct: 88 WSPEEYGNITTLQIPHGTLWKPDILLFNSANEHFDASFPVHMVVSSNGDVLFAPPGIVSF 147 Query: 467 PISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVID 571 S+ + +P D Q C KFGS + ++D ID Sbjct: 148 SCSLSMTWFPYDQQVCYLKFGSWTYGK-KLDLQID 181 >UniRef50_UPI0000E47C58 Cluster: PREDICTED: similar to nicotinic acetylcholine receptor beta 5 subunit; n=1; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to nicotinic acetylcholine receptor beta 5 subunit - Strongylocentrotus purpuratus Length = 477 Score = 60.1 bits (139), Expect = 7e-08 Identities = 32/102 (31%), Positives = 50/102 (49%), Gaps = 3/102 (2%) Frame = +2 Query: 260 LQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLLNAAATTAGDYALRA--RVSNNG 430 L + W D L W + + ++ + +W PD+ L N A + DYA + V + G Sbjct: 58 LDVRWHDDYLVWEPTRYNNVKNFKITRDDVWMPDLWLYNNAGSRYEDYAAHSICSVYHTG 117 Query: 431 SVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEM 556 V W I T +M + N+P D+QTCT FG H ++E+ Sbjct: 118 KVVWQSPTIIKTHCTMDVTNFPFDVQTCTVTFGPWQHGANEI 159 >UniRef50_Q9GQ00 Cluster: Serotonin-gated chloride channel; n=4; Caenorhabditis|Rep: Serotonin-gated chloride channel - Caenorhabditis elegans Length = 489 Score = 60.1 bits (139), Expect = 7e-08 Identities = 50/183 (27%), Positives = 87/183 (47%), Gaps = 11/183 (6%) Frame = +2 Query: 44 TYIILLPFLLTCAIASAAEC-ENATSLSLMIDSLLATYDRESPP-DSKIVVNLTLHLRH- 214 T ++LL T A +C E A S +++++++ Y + P + + VN+ +H++ Sbjct: 8 TLLLLLFVHSTQAKGKRRKCPEGAWSEGKIMNTIMSNYTKMLPDAEDSVQVNIEIHVQDM 67 Query: 215 ANIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSSERL----WRPDVVLLNAAA 382 ++ E S I W D LS+ A C + RL W P+ ++N+ Sbjct: 68 GSLNEISSDFEIDILFTQLWHDSALSF-AHLPACKRNITMETRLLPKIWSPNTCMINSKR 126 Query: 383 TT---AGDYALRARVSNNGSVSWIK-RLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSD 550 TT + + + NG+V WI RL + +P ++ L +P D QTC F S HNS+ Sbjct: 127 TTVHASPSENVMVILYENGTV-WINHRLSVKSPCNLDLRQFPFDTQTCILIFESYSHNSE 185 Query: 551 EMD 559 E++ Sbjct: 186 EVE 188 >UniRef50_O62083 Cluster: Putative uncharacterized protein acr-19; n=2; Caenorhabditis|Rep: Putative uncharacterized protein acr-19 - Caenorhabditis elegans Length = 554 Score = 60.1 bits (139), Expect = 7e-08 Identities = 37/128 (28%), Positives = 65/128 (50%), Gaps = 5/128 (3%) Frame = +2 Query: 260 LQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLLNAAATTAGD-YALRARVSNNGS 433 L+M+W D L+W+ E+G + +W+PDV+L N+ + + A V G+ Sbjct: 77 LRMSWTDHYLTWDPSEFGNIKEVRLPINNIWKPDVLLYNSVDQQFDSTWPVNAVVLYTGN 136 Query: 434 VSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHN---SDEMDFVIDKRIYSMFESGA 604 V+WI I + ++ + +P D Q CT KFGS ++ +D ++ I Y +G Sbjct: 137 VTWIPPAIIRSSCAIDIAYFPFDTQHCTMKFGSWTYSGFFTDLINTTISPATYK--PNGE 194 Query: 605 WDVTDLSS 628 W++ L+S Sbjct: 195 WELLGLTS 202 >UniRef50_O46132 Cluster: Nicotinic acetylcholine receptor, alpha1 subunit; n=1; Locusta migratoria|Rep: Nicotinic acetylcholine receptor, alpha1 subunit - Locusta migratoria (Migratory locust) Length = 559 Score = 60.1 bits (139), Expect = 7e-08 Identities = 31/102 (30%), Positives = 51/102 (50%), Gaps = 2/102 (1%) Frame = +2 Query: 260 LQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 433 ++ W D +L WN ++G T V SE +W PD+VL N + A +A + + G Sbjct: 37 VEQEWNDYKLKWNPDDYGGVDTLHVPSEHIWLPDIVLTNNSEGNFEVTLATKATIYHQGL 96 Query: 434 VSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 559 V W + + ++ +P D QTC KFGS ++ ++D Sbjct: 97 VEWKPPAIYKSSCEIDVEYFPFDEQTCVLKFGSWTYDGFKVD 138 >UniRef50_A7SI11 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 404 Score = 60.1 bits (139), Expect = 7e-08 Identities = 47/177 (26%), Positives = 82/177 (46%), Gaps = 14/177 (7%) Frame = +2 Query: 125 LMIDSLLATYDRESPP---DSKIVVNLTLHLRHANIRESESTVRILAD---LQMNWIDKR 286 L+ D L +D + P + V+N T+ L+ I E ++ + ++ W D + Sbjct: 5 LVTDLLAGYHDSQRPALDNNEPTVINFTIRLQQ--IYELNGQLQKMVSSVWIEQAWWDHK 62 Query: 287 LSWNAGEWGCSTWLVSSER--LWRPDVVLLNAAATTAGDYALR----ARVSNNGSVSWIK 448 L W+ ++G +V ER +W PDVVLLN A ++ + V +NG V W+ Sbjct: 63 LQWDQSKYGGIKEVVLPERGVIWVPDVVLLNNAEKSSMGKPVNEGNPVLVESNGVVRWLA 122 Query: 449 RLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDF-VIDKRIYSMF-ESGAWDV 613 + + + M + ++P D Q C KF S + E+ +D + + ES WD+ Sbjct: 123 PVVLKSRCKMDVRSYPFDEQYCGLKFASWTGSQSELRLDAMDNDVRQNYSESSEWDL 179 >UniRef50_A7RS33 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 460 Score = 60.1 bits (139), Expect = 7e-08 Identities = 44/172 (25%), Positives = 77/172 (44%), Gaps = 11/172 (6%) Frame = +2 Query: 140 LLATYDRESPP----DSKIVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAG 304 LLA Y R P D I + + L ++ E T+ + +++ W D RL WN Sbjct: 9 LLANYSRNIIPQKYKDIPIKIKFDIALNQIIDLDERLQTITTIVWVRLYWTDFRLRWNHT 68 Query: 305 EWG-CSTWLVSSERLWRPDVVLLNAAATT---AGDYALRARVSNNGSVSWIKRLDISTPI 472 ++G +++ S +LW PD+ L N A + V+++GS+ W + Sbjct: 69 KYGGIKSFVTPSRQLWLPDITLYNNANDNYEKEKEEYYGLTVNSDGSIGWYYPTIFKSSC 128 Query: 473 SMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVID--KRIYSMFESGAWDVTDL 622 ++ + +P D Q C KFGS ++ +D I S ++G W + D+ Sbjct: 129 TIDVTYFPFDDQKCILKFGSWSYHGLSLDIFHSGPGDIKSFTDNGEWVLVDM 180 >UniRef50_Q29ND1 Cluster: GA17977-PA; n=3; Schizophora|Rep: GA17977-PA - Drosophila pseudoobscura (Fruit fly) Length = 531 Score = 59.7 bits (138), Expect = 9e-08 Identities = 41/155 (26%), Positives = 74/155 (47%), Gaps = 7/155 (4%) Frame = +2 Query: 128 MIDSLLATYDRESPP----DSKIVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLS 292 +++ LL+TY+ P + V L L+ ++ E + L + W D L Sbjct: 14 LLNHLLSTYNTLERPVANESEPLEVKFGLTLQQIIDVDEKNQLLITNLWLSLEWNDYNLR 73 Query: 293 WNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTA-GDYALRARVSNNGSVSWIKRLDIST 466 WN E+G L ++ +LW+PDV++ N+A G Y V +NGS ++ + Sbjct: 74 WNETEYGGVKDLRITPNKLWKPDVLMYNSADEGFDGTYHTNIVVKHNGSCLYVPPGIFKS 133 Query: 467 PISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVID 571 + + +P D Q C KFGS ++ +++D V++ Sbjct: 134 TCKIDITWFPFDDQHCEMKFGSWTYDGNQLDLVLN 168 >UniRef50_A7SW63 Cluster: Predicted protein; n=3; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 324 Score = 59.7 bits (138), Expect = 9e-08 Identities = 37/154 (24%), Positives = 76/154 (49%), Gaps = 10/154 (6%) Frame = +2 Query: 128 MIDSLLATYDRESPP----DSKIVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLS 292 ++ LL Y +++ P + + + L + LR ++ E + + I ++ W D L Sbjct: 4 LLKYLLQNYSKDARPVLNVNDPVQLKLGIMLRQVIDLNERDQILTINVWIRQYWKDHLLK 63 Query: 293 WNAGEWG-CSTWLVSSERLWRPDVVLLNAAATTAGDYALRAR----VSNNGSVSWIKRLD 457 WN ++G + ++ +R+W+PDV+L N G + V+++GS +W+ Sbjct: 64 WNPDDFGGIKSINIAPDRVWKPDVLLYNRTDLRFGSLNNKIDTNVIVNHDGSTTWLAPAI 123 Query: 458 ISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 559 I + + + +P D+Q+C FGS H+ ++D Sbjct: 124 IKSECKIDVRFFPFDVQSCELTFGSWTHDGLKID 157 >UniRef50_Q7KT97 Cluster: CG32975-PB, isoform B; n=69; Eumetazoa|Rep: CG32975-PB, isoform B - Drosophila melanogaster (Fruit fly) Length = 808 Score = 59.3 bits (137), Expect = 1e-07 Identities = 35/124 (28%), Positives = 59/124 (47%), Gaps = 6/124 (4%) Frame = +2 Query: 260 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTA-GDYALRARVSNNGS 433 L++ W D L WN ++G L + R+W+PDV++ N+A G Y V NNGS Sbjct: 365 LKLEWNDMNLRWNTSDYGGVKDLRIPPHRIWKPDVLMYNSADEGFDGTYQTNVVVRNNGS 424 Query: 434 VSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDKR----IYSMFESG 601 ++ + + + +P D Q C KFGS ++ ++D + I S +G Sbjct: 425 CLYVPPGIFKSTCKIDITWFPFDDQRCEMKFGSWTYDGFQLDLQLQDETGGDISSYVLNG 484 Query: 602 AWDV 613 W++ Sbjct: 485 EWEL 488 >UniRef50_O61519 Cluster: Ligand-gated ion channel protein 6; n=4; Caenorhabditis elegans|Rep: Ligand-gated ion channel protein 6 - Caenorhabditis elegans Length = 462 Score = 59.3 bits (137), Expect = 1e-07 Identities = 41/172 (23%), Positives = 80/172 (46%), Gaps = 6/172 (3%) Frame = +2 Query: 35 MSTTYIILLPFLLTCAIASAAECENATSLSLMIDSLLATYDRE-SPPDSKIVVNLTLH-L 208 M + ++LL + + + A E + + +L+ TYD + P D +V +T + Sbjct: 1 MLISCLLLLMLWILRFLTAVAFLETSNTETLLQQLFNQTYDVDMKPSDDLTMVTITPNTF 60 Query: 209 RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCST-WL-VSSERLWRPDVVLLNAA- 379 ++ +++ T++ + + W D L WN W+ +S+ R W PDV+ N Sbjct: 61 ILLSMDQTQETIQYSEEFLLRWYDPILHWNQSAVSYENDWIKISASRAWIPDVIFTNGID 120 Query: 380 ATTAGDYALR-ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 532 D ++ A + NG + + +S+P +++DN+P D+Q C GS Sbjct: 121 MDPLLDKDMQMADLRYNGEIRTSRPAVVSSPCPLEIDNFPYDVQKCNISMGS 172 >UniRef50_A7RK99 Cluster: Predicted protein; n=2; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 446 Score = 59.3 bits (137), Expect = 1e-07 Identities = 52/211 (24%), Positives = 90/211 (42%), Gaps = 14/211 (6%) Frame = +2 Query: 35 MSTTYIILLPFLLTCAIASAAECENATSLSLMIDSLLATYDRESPPDS---KIVVNLTLH 205 M T LL LL + + +NA +L D LL YDR P S + ++ LT Sbjct: 1 MLRTETCLLFLLLHGLDCANIQEQNAVRKALRAD-LLKDYDRIVGPVSHSPRSLLELTFV 59 Query: 206 LRHANIRESESTVRIL---ADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNA 376 L+ + + ++ +++ A + W D L W+ ++ S + +W PDV L+N Sbjct: 60 LKITKLNKVDTKNQVISVNAWVFQQWKDPSLQWDKAKYNLHKTRFSPKEIWVPDVSLINN 119 Query: 377 A---ATTAGDYAL---RARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRM 538 AG L V +G V WI + ++ ++++ WP D Q CT F S Sbjct: 120 GDKLVHVAGGAELFNADTVVRQSGKVDWIAQASFTSTCNLRVRFWPMDDQFCTLTFSSWT 179 Query: 539 HNSDEMDFVIDKR--IYSMFESGAWDVTDLS 625 + E+ +D + WD+ +++ Sbjct: 180 YTESEIALKMDNSGLTTGHLSNNEWDILNIT 210 >UniRef50_UPI0000E464AB Cluster: PREDICTED: similar to nicotinic acetylcholine receptor; n=1; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to nicotinic acetylcholine receptor - Strongylocentrotus purpuratus Length = 528 Score = 58.8 bits (136), Expect = 2e-07 Identities = 35/128 (27%), Positives = 60/128 (46%), Gaps = 8/128 (6%) Frame = +2 Query: 260 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYALR----ARVSN 424 ++ W D RL W+ ++G T + + LW+PD+VL N G YA+ +V Sbjct: 68 VRQRWEDYRLVWDPADYGNITMVHIPIFLLWKPDIVLYN---NVGGSYAITMLTMTQVYP 124 Query: 425 NGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDKRIYSM---FE 595 NG+V W + + + ++P D Q C KFGS H+ ++D + +E Sbjct: 125 NGTVDWFPPAVYRSSCPINIHDFPFDEQRCPLKFGSWTHDYSKIDLQPISEFVGLERFWE 184 Query: 596 SGAWDVTD 619 + WD+ + Sbjct: 185 NQEWDIAE 192 >UniRef50_UPI0000D55E50 Cluster: PREDICTED: similar to AcetylCholine Receptor family member (acr-21); n=3; Endopterygota|Rep: PREDICTED: similar to AcetylCholine Receptor family member (acr-21) - Tribolium castaneum Length = 649 Score = 58.8 bits (136), Expect = 2e-07 Identities = 38/162 (23%), Positives = 73/162 (45%), Gaps = 8/162 (4%) Frame = +2 Query: 98 ECENATSLSLMIDSLLATYDRESPPDSKIVVNLT----LHLRHA-NIRESESTVRILADL 262 EC+ + + ++ L+ YD P + LT + L H ++ E + + Sbjct: 13 ECQGDENEARLMRHLMTNYDAAVRPVENSSLPLTVIFGISLHHIIDVDEKNQILTTNCWI 72 Query: 263 QMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARV--SNNGS 433 WID L WNA ++ G + R+WRPD++L N A + V S++G Sbjct: 73 TQAWIDHHLRWNASDFAGIKVIRIPYTRVWRPDLILYNNADPQFQSSVINTNVIVSSSGE 132 Query: 434 VSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 559 V W+ + + ++ +P D+Q+C K+ S ++ +++ Sbjct: 133 VLWLSHGIYRSSCDINVEYFPFDLQSCHMKWASWTYDGYQVE 174 >UniRef50_Q23355 Cluster: Putative uncharacterized protein acr-8; n=2; Caenorhabditis|Rep: Putative uncharacterized protein acr-8 - Caenorhabditis elegans Length = 537 Score = 58.8 bits (136), Expect = 2e-07 Identities = 35/102 (34%), Positives = 50/102 (49%), Gaps = 2/102 (1%) Frame = +2 Query: 260 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYALR-ARVSNNGS 433 L+M W D RL W+ G WG L V +++W PD++L N A + A V NG Sbjct: 77 LEMQWFDYRLMWDPGRWGKIRKLHVPVDQIWIPDILLYNNADGEPHITIMSDAIVYYNGL 136 Query: 434 VSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 559 V W + S+ ++ +P D QTC KFG +N +D Sbjct: 137 VVWKPPSIYKSFCSIDIEYFPYDTQTCWMKFGGWTYNGFLLD 178 >UniRef50_P91197 Cluster: Acetylcholine receptor protein 11; n=2; Caenorhabditis|Rep: Acetylcholine receptor protein 11 - Caenorhabditis elegans Length = 461 Score = 58.8 bits (136), Expect = 2e-07 Identities = 45/181 (24%), Positives = 79/181 (43%), Gaps = 9/181 (4%) Frame = +2 Query: 56 LLPFLLTCAIASAAECENATSLSLMIDSLLATYDRESPP----DSKIVVNLTLHLRHA-N 220 L+ +L+ I + C+ + + + + LL Y+ P + V + L L+ + Sbjct: 5 LINSILSLVIIHSNLCDGSVAETKLFTDLLKGYNPLERPVQNSSQPLEVKIKLFLQQILD 64 Query: 221 IRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLV---SSERLWRPDVVLLNAAATT- 388 + E V + A L W D +L W ++G + SS+ +W+PDV+L N+AA Sbjct: 65 VDEKNQIVSVNAWLSYTWFDHKLQWEPKKYGGIQDIRFPGSSDHIWKPDVLLYNSAAEDF 124 Query: 389 AGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVI 568 + + G+V WI + + + +P D Q C KFGS + +D I Sbjct: 125 DSTFKSNLLTYHTGTVVWIPPGVLKFVCQLDVTWFPFDDQVCEMKFGSWTFHGYAIDLQI 184 Query: 569 D 571 D Sbjct: 185 D 185 >UniRef50_A7SNK1 Cluster: Predicted protein; n=2; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 526 Score = 58.8 bits (136), Expect = 2e-07 Identities = 35/108 (32%), Positives = 55/108 (50%), Gaps = 6/108 (5%) Frame = +2 Query: 260 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAA-----ATTAGDYALRARVS 421 ++MNW + L WNA E+G L +S +W PD+VL N A A T + + ++ Sbjct: 136 VRMNWNNHLLRWNASEYGGIDKLNISPTLMWLPDIVLHNNAEENVPAGTLYQFKTKVQLF 195 Query: 422 NNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFV 565 N+G W I + ++ + +P D Q C KFGS +N E++ V Sbjct: 196 NDGLCVWYAPTIIQSGCNIDITYFPFDDQLCELKFGSWTYNGLEVNIV 243 >UniRef50_A5H038 Cluster: Nicotinic acetylcholine receptor subunit 6 isoform VIII; n=1; Musca domestica|Rep: Nicotinic acetylcholine receptor subunit 6 isoform VIII - Musca domestica (House fly) Length = 396 Score = 58.8 bits (136), Expect = 2e-07 Identities = 46/184 (25%), Positives = 85/184 (46%), Gaps = 7/184 (3%) Frame = +2 Query: 38 STTYIILLPFLLTCAIASAAECENATSLSLMIDSLLATYDRESPP----DSKIVVNLTLH 205 ++ Y++LL F++ C+ L+ + LL+TY+ P + V L Sbjct: 5 TSLYLVLLIFVII-----KESCQGPHEKRLL-NHLLSTYNTLERPVANESDPLEVKFGLT 58 Query: 206 LRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAA 379 L+ ++ E + L + W D L WN E+G L ++ +LW+PDV++ N+A Sbjct: 59 LQQIIDVDEKNQLLITNLWLSLEWNDYNLRWNDSEYGGVKDLRITPNKLWKPDVLMYNSA 118 Query: 380 ATTA-GDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEM 556 G Y V +NG+ ++ + + + +P D Q C KFGS ++ +++ Sbjct: 119 DEGFDGTYHTNIVVKHNGNCLYVPPGIFKSTCKIDITWFPFDDQHCEMKFGSWTYDGNQL 178 Query: 557 DFVI 568 D V+ Sbjct: 179 DLVL 182 >UniRef50_P25162 Cluster: Acetylcholine receptor subunit beta-like 2 precursor; n=7; Diptera|Rep: Acetylcholine receptor subunit beta-like 2 precursor - Drosophila melanogaster (Fruit fly) Length = 519 Score = 58.4 bits (135), Expect = 2e-07 Identities = 44/154 (28%), Positives = 71/154 (46%), Gaps = 10/154 (6%) Frame = +2 Query: 128 MIDSLLATYDRESPPDSKIVVNLT--LHLRHANIRESESTVRILAD---LQMNWIDKRLS 292 + D LL+ Y+R P LT L L+ + + E +++ ++ W D +L Sbjct: 33 LYDDLLSNYNRLIRPVVNNTETLTVWLGLKLSQLIEVNLKNQVMTTNLWVKQRWFDYKLR 92 Query: 293 WNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNGSVSWIKRLD 457 W+ E+G L V SE +W PD+VL N G+Y + +A + G V W Sbjct: 93 WDPEEYGGVEQLYVPSEHIWVPDIVLYN---NWDGNYEVTLMTKATLKYTGEVFWEPPAI 149 Query: 458 ISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 559 + M ++ +P D Q C KFGS +N ++D Sbjct: 150 YKSSCEMNVEYFPYDEQICFMKFGSWTYNGAQVD 183 >UniRef50_A7S9T6 Cluster: Predicted protein; n=2; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 321 Score = 58.0 bits (134), Expect = 3e-07 Identities = 35/155 (22%), Positives = 76/155 (49%), Gaps = 10/155 (6%) Frame = +2 Query: 125 LMIDSLLATYDRESPPDSKI--VVNLTLHLRHANIRESESTVRILAD---LQMNWIDKRL 289 L+ L A Y P ++ VV ++ + ++ + +IL +++ W D L Sbjct: 6 LLYKHLFANYSNVVRPVKRVEEVVPVSFDIGYSQMVNLVEKNQILISNLWVRLKWYDPWL 65 Query: 290 SWNAGEWG-CSTWLVSSERLWRPDVVLLNAA-ATTAGD---YALRARVSNNGSVSWIKRL 454 +WN ++G + V +W PD+VL N + ++G+ + + + ++G+V W+ + Sbjct: 66 TWNESDFGGMKSIKVDPSCVWVPDIVLYNNVDSDSSGEMYKFTTKVNIHSDGTVQWLSPI 125 Query: 455 DISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 559 + + + + N+P D Q C +FGS ++ E++ Sbjct: 126 QVKSECKIDITNFPLDEQFCKLEFGSWAYDGFELN 160 >UniRef50_A7RS32 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 325 Score = 58.0 bits (134), Expect = 3e-07 Identities = 45/170 (26%), Positives = 77/170 (45%), Gaps = 14/170 (8%) Frame = +2 Query: 140 LLATYDRESPP----DSKIVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAG 304 L TY+++ P D + V L L L ++ + T+ ++ ++ W D RL WN Sbjct: 20 LFRTYNKDVLPKETLDKGVPVRLDLALNQIIDVNKRAQTMTVVIWVRQYWRDPRLRWNVS 79 Query: 305 EW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYAL------RARVSNNGSVSWIKRLDIS 463 + G ++ + RLW PD+ L N A DY L +++ G VS Sbjct: 80 AYDGVDNIVIKASRLWLPDITLYNNA---RDDYKLDKESQHSLTITSRGGVSRFFPTIYK 136 Query: 464 TPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDF--VIDKRIYSMFESGAW 607 + ++ + ++P D QTC K GS +N E++ V + + S +G W Sbjct: 137 SSCALNIRHFPFDDQTCILKLGSWSYNVFEVNLTNVGNGDLNSFISNGEW 186 >UniRef50_A6QL44 Cluster: Nicotinic acetylcholine receptor non-alpha subunit precursor ShAR2beta; n=1; Schistosoma haematobium|Rep: Nicotinic acetylcholine receptor non-alpha subunit precursor ShAR2beta - Schistosoma haematobium (Blood fluke) Length = 545 Score = 58.0 bits (134), Expect = 3e-07 Identities = 33/130 (25%), Positives = 64/130 (49%), Gaps = 3/130 (2%) Frame = +2 Query: 179 KIVVNLTLHL-RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWR 352 K+VV L + + + E++ +R W D L WNA ++G L + ++W Sbjct: 60 KMVVQYGLQMIQLLGLDENKQVLRTNCWAVYRWSDSLLKWNASQYGGIKELRIFPHQIWT 119 Query: 353 PDVVLLNAAATTAGDYAL-RARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFG 529 PD+ L N A ++ R V ++G++ WI++ + +++ +P D Q C +FG Sbjct: 120 PDIKLYNFADERLQEFREGRLVVDSSGNILWIQQALFRSTCQVEITYFPFDSQVCMLEFG 179 Query: 530 SRMHNSDEMD 559 S ++ ++D Sbjct: 180 SMAYDKTQLD 189 >UniRef50_O18228 Cluster: Putative uncharacterized protein lgc-7; n=4; Caenorhabditis|Rep: Putative uncharacterized protein lgc-7 - Caenorhabditis elegans Length = 439 Score = 57.6 bits (133), Expect = 4e-07 Identities = 42/180 (23%), Positives = 79/180 (43%), Gaps = 8/180 (4%) Frame = +2 Query: 65 FLLTCAIASAAECENATSLSLMIDSLLATYDRESPPDSK----IVVNLTLHLRHA-NIRE 229 F L + + E + T + D L+ YD P + +++N++++ + Sbjct: 10 FYLAISWCNLLEVDGITVAEQLKDVLMEGYDSSIRPVNNERDILIINISMNTMSVLTLDP 69 Query: 230 SESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSSER-LWRPDVVLLNAAATT-AGDYA 403 +E T+ ++ + W D+ L WN ++ TWL E LW PD + + T D + Sbjct: 70 AEETINFSSEFILQWKDEFLFWNKSDYNI-TWLKLKESFLWTPDTTVSTSIDTNYLIDAS 128 Query: 404 LR-ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDKRI 580 R V ++G+V + M +D +P D QTC K G + + E+ ++ + I Sbjct: 129 ERYVSVKHDGTVRQSIYAVFTNLCDMNVDKFPYDQQTCMIKMGPWSYTTQEVTCIVGRDI 188 >UniRef50_A7RUG1 Cluster: Predicted protein; n=2; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 497 Score = 57.6 bits (133), Expect = 4e-07 Identities = 41/176 (23%), Positives = 84/176 (47%), Gaps = 14/176 (7%) Frame = +2 Query: 128 MIDSLLATYDRESPP-----DSKIVVNLTLHL-RHANIRESESTVRILADLQMNWIDKRL 289 ++ LL Y++++ P ++ +V L L + N+ + + ++ W + L Sbjct: 15 LLGDLLKGYNKDAHPVPILNKTQYMVTFGLELVQLVNVDDKNQIITTNVWVRQRWTNLLL 74 Query: 290 SWNAGEWGCSTWL-VSSERLWRPDVVLLNAAAT--TAG--DYALRARVSNNGSVSWIKRL 454 W+ ++G T + + + ++W PD+VL N+A + + G Y R ++++G +W Sbjct: 75 KWDPDKYGGITRVRIDASKIWIPDIVLYNSADSEFSGGLEKYKTRVILNHDGVNAWYSPA 134 Query: 455 DISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDKR-IYS--MFESGAWDV 613 + + + +P D QTC KFGS ++D DK ++S +S WD+ Sbjct: 135 SFRSTCQIDVTFFPFDQQTCFMKFGSWTFEVVDLDIFADKSPLHSSQYMKSAEWDL 190 >UniRef50_UPI0000E47621 Cluster: PREDICTED: similar to nicotinic acetylcholine receptor subunit type G, partial; n=1; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to nicotinic acetylcholine receptor subunit type G, partial - Strongylocentrotus purpuratus Length = 283 Score = 57.2 bits (132), Expect = 5e-07 Identities = 44/180 (24%), Positives = 77/180 (42%), Gaps = 8/180 (4%) Frame = +2 Query: 104 ENATSLSLMIDSLLATYDRESP-PDSKIVVNLTLHLRHA-NIRESESTVRILADLQMNWI 277 E A +S ++D +T R + I V + L + + ++ E+ + + W Sbjct: 11 EEALLVSRLLDHGYSTIVRPVMYQEDTITVKIDLAIVNLLDMDEANQIMTANTFMTQEWN 70 Query: 278 DKRLSWNAGE-WGCSTWLVSSERLWRPDVVLLNAA--ATTAGDYALRARVSNNGSVSWIK 448 D L W E W + V +WRPD++L N A G A + +G+V+W Sbjct: 71 DAFLQWEPSESWNITDVQVPINNIWRPDIILHNNANDELNGGIRWTHAWIRYDGTVTWKT 130 Query: 449 RLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDKRIYSMFE---SGAWDVTD 619 + + M +P D Q C+ K GS +N DE++ + + + +G WD+ D Sbjct: 131 NYILMSACPMNPLYFPFDTQNCSLKLGSWTYNEDEINVIANSTSGDATQYQPNGEWDLID 190 >UniRef50_UPI0000ECB6ED Cluster: Acetylcholine receptor subunit alpha precursor.; n=1; Gallus gallus|Rep: Acetylcholine receptor subunit alpha precursor. - Gallus gallus Length = 352 Score = 57.2 bits (132), Expect = 5e-07 Identities = 46/166 (27%), Positives = 75/166 (45%), Gaps = 11/166 (6%) Frame = +2 Query: 68 LLTCAIASAAEC-ENATSLSLMIDSLLATYDRESPPDSK----IVVNLTLHL-RHANIRE 229 LL + A A C E+ T L +D L Y + P +VV + L L + N+ E Sbjct: 8 LLIFSAAGPALCYEHETRL---VDDLFRDYSKVVRPVENHRDAVVVTVGLQLIQLINVDE 64 Query: 230 SESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYAL 406 V L+ W D L WN ++G + + S+ +WRPD+VL N A GD+A+ Sbjct: 65 VNQIVTTNVRLKQQWTDINLKWNPDDYGGVKQIRIPSDDIWRPDLVLYNNA---DGDFAI 121 Query: 407 ----RARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 532 + + + G ++W + + + +P D Q C+ K G+ Sbjct: 122 VKYTKVLLEHTGKITWTPPAIFKSYCEIIVTYFPFDQQNCSMKLGT 167 >UniRef50_A7S2J7 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 462 Score = 57.2 bits (132), Expect = 5e-07 Identities = 49/179 (27%), Positives = 83/179 (46%), Gaps = 13/179 (7%) Frame = +2 Query: 35 MSTTYIILLPFLLTCAIASAAECENA---TSLSLMIDSLLATYDRESPP---DS-KIVVN 193 +S +ILL LL S+ + A T+ ++ L YD E P DS K+ V Sbjct: 7 ISLLLLILLVLLLAGFSESSRKRRGASRETAEKRLLADLFRNYDSEVRPVFNDSDKVNVE 66 Query: 194 LTLHLRHANIRESEST-VRILADLQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVL 367 +L L S+S V + ++ W + L+WN ++G + ++ ++W PD++L Sbjct: 67 FSLSLIQIIAVNSKSQLVTVSVWIRQKWTNPMLAWNTSKYGGIESVNLNPAKVWIPDIIL 126 Query: 368 LNAAATT-AGD---YALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 532 N A T AG Y S++G+ W ++ ++ + +P D Q C+ KFGS Sbjct: 127 YNNADETYAGGLEKYKTSVIASSDGTQEWNSPASFTSTCNINVRYFPFDSQNCSLKFGS 185 >UniRef50_A0EIZ9 Cluster: Nicotinic acetylcholine receptor beta2 subunit; n=1; Apis mellifera|Rep: Nicotinic acetylcholine receptor beta2 subunit - Apis mellifera (Honeybee) Length = 427 Score = 57.2 bits (132), Expect = 5e-07 Identities = 42/162 (25%), Positives = 76/162 (46%), Gaps = 10/162 (6%) Frame = +2 Query: 101 CENATSLSLMIDS---LLATYDRESPPDSKIV--VNLTLHLRHANIRESESTVRILADLQ 265 C++ TS S + L YDR+ P+ K ++ L ++H N+ E TV L+ Sbjct: 28 CKDITSTSALYRLKLYLFCDYDRDIIPEQKNATKIDFGLSIQHYNVDEYSHTVDFHVMLK 87 Query: 266 MNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVL--LNAAATTAGDYALRARVSNNGSV 436 + W L+W + E+ ++ V S +W PD+V+ + + ++ V N+G++ Sbjct: 88 LMWEQSHLTWKSSEFDSINSIRVKSYEIWVPDIVMHSVTSVGIDLEMPSVECIVFNSGTI 147 Query: 437 SWIKRLDISTPISMQLDN--WPNDMQTCTFKFGSRMHNSDEM 556 + TP+ + D+ WP D+ CT S H S+E+ Sbjct: 148 LCVP-FTTYTPV-CEYDHTWWPYDILNCTIHIASWSHGSNEI 187 >UniRef50_UPI0000D56893 Cluster: PREDICTED: similar to CG6698-PA; n=1; Tribolium castaneum|Rep: PREDICTED: similar to CG6698-PA - Tribolium castaneum Length = 419 Score = 56.8 bits (131), Expect = 7e-07 Identities = 37/152 (24%), Positives = 68/152 (44%), Gaps = 5/152 (3%) Frame = +2 Query: 188 VNLTLHLRHANIRESESTVRILADLQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVV 364 V L L + E +S ++ + + W D++L WN E+G +T + +W P++ Sbjct: 224 VGLKLGTNIVTLNEYKSVLQYSGTISLTWHDEKLHWNTSEYGDINTLHIFRREIWIPELF 283 Query: 365 LLNAAATTAGDYA--LRARVSNNGSVSWIKRLDISTPISM-QLDNWPNDMQTCTFKFG-S 532 L NA A G+ V++ G V WI ++I++ S L WP D C G Sbjct: 284 LFNAIAEN-GELLEDTMLTVNSTGHVKWITTININSWCSPDDLGRWPRDEHQCDIVLGFF 342 Query: 533 RMHNSDEMDFVIDKRIYSMFESGAWDVTDLSS 628 + ++ F ++ ++ S W + ++ S Sbjct: 343 NEFQNLQLAFNANESTFNCPYSSRWAILEVES 374 >UniRef50_Q4RZC6 Cluster: Chromosome 1 SCAF14944, whole genome shotgun sequence; n=1; Tetraodon nigroviridis|Rep: Chromosome 1 SCAF14944, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 547 Score = 56.8 bits (131), Expect = 7e-07 Identities = 28/105 (26%), Positives = 50/105 (47%), Gaps = 2/105 (1%) Frame = +2 Query: 260 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATT-AGDYALRARVSNNGS 433 ++ W D L WN ++ G + S +WRPD+VL N A +G ++ NG Sbjct: 139 IRQRWNDAYLKWNKEDYDGLEVIHIPSSLVWRPDLVLYNKADDDFSGPMDTNVKLRYNGE 198 Query: 434 VSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVI 568 ++W + + + +P D Q C FGS +N +++D ++ Sbjct: 199 ITWDAPAITKSSCVVDVSYFPFDSQECNLTFGSWTYNGNQVDIIM 243 >UniRef50_UPI00015B6212 Cluster: PREDICTED: similar to nicotinic acetylcholine receptor alpha9 subunit; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to nicotinic acetylcholine receptor alpha9 subunit - Nasonia vitripennis Length = 443 Score = 56.4 bits (130), Expect = 9e-07 Identities = 53/194 (27%), Positives = 88/194 (45%), Gaps = 13/194 (6%) Frame = +2 Query: 29 HKMSTTYIILLPFLL--TCAIASAAECENATSLS--LMIDS-LLATYDRESPP--DSKIV 187 +++S +ILL L+ C + + C A + S L ++ L YD P K Sbjct: 4 YRLSLVLVILLGLLVHVMCVGETNSTCSLAAAKSPHLRLNRYLFCDYDITVRPVIHHKNA 63 Query: 188 VNLTLHLRHANIR-ESESTVRILADLQM-NWIDKRLSWNAGEW-GCSTWLVSSERLWRPD 358 N+++H I ES+ IL +W+D+ L+WN ++ G + V S ++W PD Sbjct: 64 TNISIHFDPLRIDFMDESSTFILHTWNTWSWMDEFLTWNPKDFDGINETRVESAKIWTPD 123 Query: 359 VVLLNAA---ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFG 529 + L N+A T G ++ + N+G + I + T + WP D QTC + Sbjct: 124 LALYNSADMTETQIGIPSVPCILVNDGQLVCIAPVKYVTHCTTDFTYWPYDEQTCNIRLS 183 Query: 530 SRMHNSDEMDFVID 571 S N+ +D ID Sbjct: 184 S--WNNHALDINID 195 >UniRef50_UPI0000E4930A Cluster: PREDICTED: similar to nicotinic acetylcholine receptor subunit Dalpha7; n=1; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to nicotinic acetylcholine receptor subunit Dalpha7 - Strongylocentrotus purpuratus Length = 1094 Score = 56.4 bits (130), Expect = 9e-07 Identities = 29/102 (28%), Positives = 50/102 (49%), Gaps = 2/102 (1%) Frame = +2 Query: 260 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGD-YALRARVSNNGS 433 ++ W D L+WN E+G + V + +WRPD+++ N+AA + + V++ G Sbjct: 757 MRQRWTDPTLAWNKSEYGGLDKIRVLPDMIWRPDILVYNSAAPKFDPTFHTKVTVTSEGL 816 Query: 434 VSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 559 WI T + + +P D+Q C KFGS + +D Sbjct: 817 CEWIPPGIFKTSCPIDVTYFPFDIQECEIKFGSWTYGGFTVD 858 >UniRef50_Q17BK9 Cluster: Nicotinic acetylcholine receptor, putative; n=1; Aedes aegypti|Rep: Nicotinic acetylcholine receptor, putative - Aedes aegypti (Yellowfever mosquito) Length = 378 Score = 56.4 bits (130), Expect = 9e-07 Identities = 35/128 (27%), Positives = 61/128 (47%), Gaps = 4/128 (3%) Frame = +2 Query: 200 LHLRHANIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNA 376 L L++ +I + + I ++++W D+ L+W+ E G +V S+ +W PD++ A Sbjct: 3 LVLQNFDIDDDRQKLFINVWIRLSWKDQFLTWDPREHNGLKDLMVDSKDIWLPDMMPYAA 62 Query: 377 AATTAGDYAL---RARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNS 547 + D + + V ++G V I D + NWP D CT +FG S Sbjct: 63 YYSNNLDVSCTSPKCSVLSDGEVRCIPACDYHSLCETDFRNWPFDRMNCTIRFGMWAEYS 122 Query: 548 DEMDFVID 571 +E+DF D Sbjct: 123 NEVDFTAD 130 >UniRef50_Q07001 Cluster: Acetylcholine receptor subunit delta precursor; n=38; Gnathostomata|Rep: Acetylcholine receptor subunit delta precursor - Homo sapiens (Human) Length = 517 Score = 56.4 bits (130), Expect = 9e-07 Identities = 38/142 (26%), Positives = 67/142 (47%), Gaps = 7/142 (4%) Frame = +2 Query: 152 YDRESPP----DSKIVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEWG- 313 Y++E P + + V L L L + +++E E T+ ++ W D RL WNA E+G Sbjct: 38 YNKELRPVAHKEESVDVALALTLSNLISLKEVEETLTTNVWIEHGWTDNRLKWNAEEFGN 97 Query: 314 CSTWLVSSERLWRPDVVL-LNAAATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDN 490 S + + +W P++VL N + Y+ V + G V W+ + + + Sbjct: 98 ISVLRLPPDMVWLPEIVLENNNDGSFQISYSCNVLVYHYGFVYWLPPAIFRSSCPISVTY 157 Query: 491 WPNDMQTCTFKFGSRMHNSDEM 556 +P D Q C+ KF S + + E+ Sbjct: 158 FPFDWQNCSLKFSSLKYTAKEI 179 >UniRef50_P36544 Cluster: Neuronal acetylcholine receptor subunit alpha-7 precursor; n=65; Euteleostomi|Rep: Neuronal acetylcholine receptor subunit alpha-7 precursor - Homo sapiens (Human) Length = 502 Score = 56.4 bits (130), Expect = 9e-07 Identities = 32/124 (25%), Positives = 58/124 (46%), Gaps = 3/124 (2%) Frame = +2 Query: 260 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSNNGS 433 LQM+W D L WN E+ G T ++W+PD++L N+A + V+++G Sbjct: 78 LQMSWTDHYLQWNVSEYPGVKTVRFPDGQIWKPDILLYNSADERFDATFHTNVLVNSSGH 137 Query: 434 VSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDKR-IYSMFESGAWD 610 ++ + + + +P D+Q C KFGS + +D + + I +G WD Sbjct: 138 CQYLPPGIFKSSCYIDVRWFPFDVQHCKLKFGSWSYGGWSLDLQMQEADISGYIPNGEWD 197 Query: 611 VTDL 622 + + Sbjct: 198 LVGI 201 >UniRef50_Q10052 Cluster: Gaba/glycine receptor family (See gbr) protein 3; n=4; Caenorhabditis|Rep: Gaba/glycine receptor family (See gbr) protein 3 - Caenorhabditis elegans Length = 438 Score = 56.0 bits (129), Expect = 1e-06 Identities = 49/171 (28%), Positives = 80/171 (46%), Gaps = 10/171 (5%) Frame = +2 Query: 74 TCAIASAAECE-NATSLSLMIDSLLATYDRESPPDSKIVVNLTLHLRHANIRE-SESTVR 247 T ++ A CE N+ ++ LL YD+ P + V +++ L +I SE + Sbjct: 20 TESLVDPAHCEYNSNHRKSILTDLLQDYDKTMVPSNNSV-QVSVELTVQDISSISEISSS 78 Query: 248 ILADLQMN--WIDKRLSWNAGEWGCSTWLVS--SERLWRPDVVLLNAAATTAGDYA---L 406 +AD+ + W D RL + + L S SERLW P+V +N+ +T + Sbjct: 79 FIADVWFSQVWYDPRLEYRNISCKTNLSLDSYVSERLWTPNVCFVNSKSTQVHKSPASNI 138 Query: 407 RARVSNNGSVSWIK-RLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEM 556 + NG+V W+ R+ +S P S +L +P D Q C F S +N E+ Sbjct: 139 LLIIYPNGTV-WLNYRVQVSAPCSFELSRFPIDAQECHLVFESYSYNIAEV 188 >UniRef50_Q60S81 Cluster: Neuronal acetylcholine receptor subunit eat-2 precursor; n=1; Caenorhabditis briggsae|Rep: Neuronal acetylcholine receptor subunit eat-2 precursor - Caenorhabditis briggsae Length = 477 Score = 56.0 bits (129), Expect = 1e-06 Identities = 42/155 (27%), Positives = 72/155 (46%), Gaps = 7/155 (4%) Frame = +2 Query: 128 MIDSLLATYDRESPP--DSKIVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLS 292 ++ L YD P D VN+ L L + ++ E + ++ Q W D ++ Sbjct: 26 LLKDLREGYDPMERPVSDHMKPVNVKLRLILQQLVDVDEKNQVITLVVWTQYTWNDYKMK 85 Query: 293 WNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTA-GDYALRARVSNNGSVSWIKRLDIST 466 W+ E+G T L + LW+PD++L N+A + + VSN+G+V + + Sbjct: 86 WSPEEYGNITSLQIPFGTLWKPDILLFNSANEHFDSSFPVNMVVSNDGNVLFAPPGIMQF 145 Query: 467 PISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVID 571 S+ + +P D Q C KFGS + ++D ID Sbjct: 146 SCSLSMTWFPYDEQVCYLKFGSWTYGK-KLDLRID 179 >UniRef50_UPI000058896A Cluster: PREDICTED: similar to cholinergic receptor neuronal nicotinic alpha protein 2; n=5; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to cholinergic receptor neuronal nicotinic alpha protein 2 - Strongylocentrotus purpuratus Length = 329 Score = 55.6 bits (128), Expect = 2e-06 Identities = 35/108 (32%), Positives = 58/108 (53%), Gaps = 3/108 (2%) Frame = +2 Query: 218 NIRESESTVRILADLQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLLNA--AATT 388 NIR S S +R +M+W+D R+ WN E+G S + V S ++ PD+ L N+ + T Sbjct: 39 NIRMSLSNLR-----EMHWVDPRMVWNPLEYGNISKFRVHSSEVFVPDITLYNSHSPSKT 93 Query: 389 AGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 532 D + ++N+G+V + + I S+ L ++P D C K+GS Sbjct: 94 MSD-DISTLMTNHGTVYYTPPVAIEAACSLDLKDYPYDSHICRLKWGS 140 >UniRef50_Q19351 Cluster: Ligand-gated ion channel protein 3; n=3; Caenorhabditis|Rep: Ligand-gated ion channel protein 3 - Caenorhabditis elegans Length = 355 Score = 55.6 bits (128), Expect = 2e-06 Identities = 44/180 (24%), Positives = 82/180 (45%), Gaps = 6/180 (3%) Frame = +2 Query: 35 MSTTYIILLPFLLTCAIASAAECENAT-SLSLMIDSLLATYDRESPPDSKIVVNLTLHLR 211 M +++ + F+ T + A E S S + LL +++ SPPD ++ ++ + L Sbjct: 41 MQCSFLTIFIFITTVTVGVAEFSEQYQGSSSRLTRHLLEKHNKCSPPDGRVDISHNIELV 100 Query: 212 HA-NIRESESTVRILADLQMNWIDKRLSWNAGEW-GCS-TWLVSSERLWRPDVVLLNAAA 382 H I E +++L + W D LSW E+ G TWL +W PD+++ N Sbjct: 101 HIIGINELNQNMQVLVYIVQQWTDASLSWKVEEFRGIKHTWL-PEHSIWIPDIIVFNTLE 159 Query: 383 TTAGDYALRA--RVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEM 556 A+R+ +VS G V++ + + + +P D Q +F S ++ D++ Sbjct: 160 HKMLLEAVRSPIKVSYTGEVTYAYPAIYTVLCQIGIATFPFDDQVYV-QFASWAYDEDKI 218 >UniRef50_O17848 Cluster: Putative uncharacterized protein acr-18; n=2; Caenorhabditis|Rep: Putative uncharacterized protein acr-18 - Caenorhabditis elegans Length = 510 Score = 55.6 bits (128), Expect = 2e-06 Identities = 34/139 (24%), Positives = 63/139 (45%), Gaps = 6/139 (4%) Frame = +2 Query: 221 IRESESTVRILADLQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLLNAAATTA-- 391 + E + V I L++ WID+ L+W+ ++G S V + ++W+PDV++ N A Sbjct: 69 VDERDQIVNIYCWLELYWIDETLTWDPKKFGNLSRIHVPAHKIWKPDVLVYNNANMNVEE 128 Query: 392 GDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVID 571 + A V N G V + + ++ L +P D Q C F S + ++D Sbjct: 129 NEMETNAIVDNTGRVMLFRSMITDISCNLNLQQFPFDQQICFVTFASWSMDGSKLDLSAT 188 Query: 572 KRIYSM---FESGAWDVTD 619 + ++ + W +TD Sbjct: 189 PKTDNLELYIRNTEWGLTD 207 >UniRef50_Q7PJX0 Cluster: ENSANGP00000022703; n=1; Anopheles gambiae str. PEST|Rep: ENSANGP00000022703 - Anopheles gambiae str. PEST Length = 223 Score = 55.2 bits (127), Expect = 2e-06 Identities = 38/160 (23%), Positives = 75/160 (46%), Gaps = 9/160 (5%) Frame = +2 Query: 173 DSKIVVNLTL--HLRHANIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSER 343 D VN+T+ ++ ES++ +++ +++ W D+ L WN+ EW G + SE Sbjct: 64 DHTQTVNVTVAYYVLTYEFEESDNLLQLGVWMELQWTDEYLRWNSTEWSGIERLAIGSEE 123 Query: 344 LWRPDVVLLNA--AATTAGDYA-LRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTC 514 +W PD ++ + A + V+ NG+V + ++ WP D+ C Sbjct: 124 IWMPDFRHFSSYYNPEDLNECANPKCSVAPNGTVVCLPVCGMNAKCDADYSRWPFDVHRC 183 Query: 515 TFKFGSRMHNSDEMD-FVIDKRI--YSMFESGAWDVTDLS 625 +G+ ++ DE+D ++D + F+S W+V L+ Sbjct: 184 NLWYGTWANSMDEVDVHILDVCLGRNPEFKSPKWNVISLA 223 >UniRef50_Q67X94 Cluster: Putative uncharacterized protein lgc-2; n=3; Caenorhabditis|Rep: Putative uncharacterized protein lgc-2 - Caenorhabditis elegans Length = 509 Score = 55.2 bits (127), Expect = 2e-06 Identities = 42/199 (21%), Positives = 89/199 (44%), Gaps = 12/199 (6%) Frame = +2 Query: 128 MIDSLLATYDRESPPDSKIVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAG 304 + + LL+ ++ +PPD + V L L H I E + T+ +L + +W+D L+W+ Sbjct: 70 LTEYLLSRHNLNAPPDGLLYVEYELELVHILGIDELKQTMTVLIYVDEHWVDPSLTWDPA 129 Query: 305 EWG--CSTWLVSSERLWRPDVVLLNAAATTAGDY-----ALR--ARVSNNGSVSWIKRLD 457 +G TW + +++W PD+++ N + + A+R AR+ NG++ Sbjct: 130 LFGGITKTW-IPLDKIWVPDIIVFNMVKSNRLAHEDLLSAVRAPARIHYNGTIVASHPAV 188 Query: 458 ISTPISMQLDNWPNDMQTCTFKFGSRMHNSDE--MDFVIDKRIYSMFESGAWDVTDLSSA 631 + + + ++P D Q C + S + ++ + D + + W + +L+ + Sbjct: 189 HTVSCEINIRHFPLDDQRCAIEIASWAYGQEKIRLHAHTDHSLEHYKRNEEWHLLNLNVS 248 Query: 632 VXSQDRGEVEARVAMFXMS 688 + VE F +S Sbjct: 249 EEKYEHEGVEVSEVKFEIS 267 >UniRef50_Q2XWL2 Cluster: Nicotinic acetylcholine receptor subunit type A; n=1; Lymnaea stagnalis|Rep: Nicotinic acetylcholine receptor subunit type A - Lymnaea stagnalis (Great pond snail) Length = 485 Score = 55.2 bits (127), Expect = 2e-06 Identities = 37/149 (24%), Positives = 66/149 (44%), Gaps = 7/149 (4%) Frame = +2 Query: 182 IVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRP 355 I VN + L+ ++ E + L+M W L W+ E+G T + V + +W P Sbjct: 53 INVNFGIILQQIIDVDEKNQIIHTNIWLRMTWNAANLMWDPKEYGNLTSIRVPKQMVWVP 112 Query: 356 DVVLLNAAATTAGD-YALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 532 D++L N+A+ D Y ++ NG+ W+ + ++ + +P D Q C K+GS Sbjct: 113 DILLYNSASDGFDDTYPTNVVINYNGNCLWVPPGMFKSTCAIDITWFPFDDQRCNLKYGS 172 Query: 533 RMHNSDEMDFVIDK----RIYSMFESGAW 607 H ++ D I + +G W Sbjct: 173 WTHEGHLLNLTADSDDGGDISTFIRNGEW 201 >UniRef50_Q2XWK9 Cluster: Nicotinic acetylcholine receptor subunit type D; n=1; Lymnaea stagnalis|Rep: Nicotinic acetylcholine receptor subunit type D - Lymnaea stagnalis (Great pond snail) Length = 554 Score = 55.2 bits (127), Expect = 2e-06 Identities = 35/135 (25%), Positives = 63/135 (46%), Gaps = 2/135 (1%) Frame = +2 Query: 179 KIVVNLTLHLRHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRP 355 K+++ +TL + ++ E + L W D++L WN ++ L + LW+P Sbjct: 106 KVLIGITL-TQIFDLDEKNQVLTTNVWLDQEWTDQKLHWNPTDYNDLKRLRIPCRHLWKP 164 Query: 356 DVVLLNAAAT-TAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 532 D+VL N+ T G A V + G V W + + + + +P D Q C+ K GS Sbjct: 165 DIVLYNSVEDYTDGYMQSLAMVHHTGVVFWPPIVRFQSTCQVDITYFPFDDQVCSMKLGS 224 Query: 533 RMHNSDEMDFVIDKR 577 ++ ++D +D R Sbjct: 225 WAYDGFQVD--VDNR 237 >UniRef50_A7S2N9 Cluster: Predicted protein; n=3; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 545 Score = 55.2 bits (127), Expect = 2e-06 Identities = 38/152 (25%), Positives = 76/152 (50%), Gaps = 8/152 (5%) Frame = +2 Query: 182 IVVNLTLHLRHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPD 358 +V+ +++H + ++ E + ++ ++ W + L WN +G + VS ++W PD Sbjct: 77 VVLGMSVH-QIIDVYEKDQIIKTSFWVRQIWYNPFLRWNETFYGGIKEINVSPLQVWTPD 135 Query: 359 VVLLNAA-ATTAG---DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKF 526 +VL N A A+T G ++ R VS++G W+ + S+ ++++ +P D Q C+ KF Sbjct: 136 LVLYNNADASTDGSLENFKTRIIVSSDGKNMWLAPVIFSSSCTIKIKYFPFDDQYCSLKF 195 Query: 527 GSRMHNSDEMDF---VIDKRIYSMFESGAWDV 613 GS + +D + +G WD+ Sbjct: 196 GSWTFDGFHLDLKPEAPQASLSKFIPNGEWDL 227 >UniRef50_UPI0000586C99 Cluster: PREDICTED: similar to nicotinic acetylcholine receptor subunit type A; n=1; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to nicotinic acetylcholine receptor subunit type A - Strongylocentrotus purpuratus Length = 357 Score = 54.8 bits (126), Expect = 3e-06 Identities = 36/126 (28%), Positives = 58/126 (46%), Gaps = 7/126 (5%) Frame = +2 Query: 272 WIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYALRAR----VSNNGSV 436 W D+ L W + T L + + ++W PD VL N + D + V ++GSV Sbjct: 130 WRDEYLMWEPRAYNNLTVLRIPASKIWLPDTVLYNTRQSN-NDQLMTVETLTIVKSDGSV 188 Query: 437 SWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDKRIYSMFE--SGAWD 610 W L + + S+ + +P D Q C K GS H+ +D+ +D S E +G WD Sbjct: 189 DWSAPLTMISECSINVYYYPFDQQECALKMGSWQHDRKFIDY-LDGTADSATEQRNGEWD 247 Query: 611 VTDLSS 628 T + + Sbjct: 248 TTSIKA 253 >UniRef50_P47870-2 Cluster: Isoform Long of P47870 ; n=22; Eumetazoa|Rep: Isoform Long of P47870 - Homo sapiens (Human) Length = 512 Score = 54.8 bits (126), Expect = 3e-06 Identities = 44/182 (24%), Positives = 79/182 (43%), Gaps = 10/182 (5%) Frame = +2 Query: 47 YIILLPFLLTCAIASAAECENATSLSLM---IDSLLATYDRESPPD---SKIVVNLTLHL 208 Y + F L A A + +++SL+ +D LL YD PD + V + + + Sbjct: 9 YFGIWSFPLIIAAVCAQSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDI 68 Query: 209 RHAN-IRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAAT 385 + + E + Q W DKRLS+N + +++LW PD LN + Sbjct: 69 ASIDMVSEVNMDYTLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLNDKKS 128 Query: 386 TAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEM 556 ++ R+ +G+V + R+ + M L +P D Q CT + S + +D++ Sbjct: 129 FVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDI 188 Query: 557 DF 562 +F Sbjct: 189 EF 190 >UniRef50_Q9XTY8 Cluster: Putative uncharacterized protein lgc-25; n=3; Caenorhabditis|Rep: Putative uncharacterized protein lgc-25 - Caenorhabditis elegans Length = 502 Score = 54.8 bits (126), Expect = 3e-06 Identities = 31/128 (24%), Positives = 56/128 (43%), Gaps = 4/128 (3%) Frame = +2 Query: 188 VNLTLHLRHAN-IRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVV 364 VN+ L + H + E E T + + WID+ + W+A + + +S+ LW+P + Sbjct: 54 VNVFLSIAHVEKVDEHEQTALVHGHIWATWIDEYMQWDAKKENVTKLTISAHSLWQPALA 113 Query: 365 LLNAAATTAGDY---ALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSR 535 L N+A + A+ A V + G V NWP D Q+C Sbjct: 114 LYNSARGNSWHLYMGAMPATVYSTGKVWSTGTFSFYVTCQFDFTNWPFDQQSCPIVIADW 173 Query: 536 MHNSDEMD 559 ++N ++++ Sbjct: 174 VYNLNQVN 181 >UniRef50_Q9N5U8 Cluster: Acetylcholine receptor protein 21; n=2; Caenorhabditis|Rep: Acetylcholine receptor protein 21 - Caenorhabditis elegans Length = 469 Score = 54.8 bits (126), Expect = 3e-06 Identities = 35/151 (23%), Positives = 74/151 (49%), Gaps = 8/151 (5%) Frame = +2 Query: 140 LLATYDRESPPD--SKIVVNLTLHLRHANIRESESTVRILAD---LQMNWIDKRLSWNAG 304 LL Y+ E P SK +N+T I + + +IL ++++W+D +L W+ Sbjct: 7 LLYDYNNEVRPSVHSKEPINVTFVFSLTQIIDVDERNQILTTNSWIRLHWVDYKLVWDPR 66 Query: 305 EWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYALRARVSNN--GSVSWIKRLDISTPIS 475 + T + + S+++W+PD++L N A + V + G++ W ++ Sbjct: 67 LYQNVTRIHIPSDKIWKPDIILYNNADAQYMKSVMSTDVIVDYLGNIHWPLSAIFTSSCP 126 Query: 476 MQLDNWPNDMQTCTFKFGSRMHNSDEMDFVI 568 + + ++P D QTC K+ S ++ ++D ++ Sbjct: 127 LDVKHYPFDRQTCILKYASWAYDGTKIDLLL 157 >UniRef50_Q6TMY0 Cluster: Nicotinic acetylcholine receptor non-alpha subunit precursor; n=3; Schistosoma|Rep: Nicotinic acetylcholine receptor non-alpha subunit precursor - Schistosoma bovis (Blood fluke) Length = 740 Score = 54.8 bits (126), Expect = 3e-06 Identities = 26/116 (22%), Positives = 56/116 (48%), Gaps = 2/116 (1%) Frame = +2 Query: 218 NIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAG 394 ++ E + + L + W D WNA ++ + + ER+W+PD++L N+A+ Sbjct: 74 DVDEKNQVLSTIIWLDLKWSDYHFHWNASDYENIRQINLPPERIWKPDILLYNSASEKFD 133 Query: 395 D-YALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 559 + + V N G++ W+ + ++++ +P D Q C K G+ + + +D Sbjct: 134 QIFPTKVIVRNTGNIQWVPPGLFHSICDIEVNWFPFDSQNCIMKLGTWTYQGNTVD 189 >UniRef50_Q22224 Cluster: Putative uncharacterized protein acr-14; n=2; Caenorhabditis|Rep: Putative uncharacterized protein acr-14 - Caenorhabditis elegans Length = 500 Score = 54.8 bits (126), Expect = 3e-06 Identities = 53/191 (27%), Positives = 84/191 (43%), Gaps = 9/191 (4%) Frame = +2 Query: 35 MSTTYIILLPFLLTCAIASAAECENATSLSLMIDSLLATYDRESPPDSKIVVNLTLHLRH 214 MS + ILL F + S E L DS + S P + V L+ + Sbjct: 1 MSFVFFILLTFYIQVK-GSVDEYRLLQYLKENYDSFERPVENSSAP-LDVKVRFLLN-QI 57 Query: 215 ANIRESESTVRILADLQMNWIDKRLSWNAGEWG------CSTWLVSSERLWRPDVVLLNA 376 ++ E + ILA + +W D +L+W+ +G S +S +LWRPDV+L N+ Sbjct: 58 MDVDEKNQVMSILAYMDYHWNDYKLTWDPKLFGGIRDVRFSGDDDASFKLWRPDVLLFNS 117 Query: 377 AATT-AGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSD- 550 + + Y+ R VS+NG V + + +P D QTC K GS +N Sbjct: 118 VSESFDSTYSSRFIVSSNGDVQQNPPGIFRFVCQIDVTYYPFDKQTCFLKLGSWTYNGQY 177 Query: 551 -EMDFVIDKRI 580 +DF++ + I Sbjct: 178 INLDFLLTQII 188 >UniRef50_Q6F6K3 Cluster: Acetylcholine receptor protein 17, isoform b; n=4; Caenorhabditis|Rep: Acetylcholine receptor protein 17, isoform b - Caenorhabditis elegans Length = 515 Score = 54.4 bits (125), Expect = 4e-06 Identities = 39/178 (21%), Positives = 83/178 (46%), Gaps = 9/178 (5%) Frame = +2 Query: 50 IILLPFLLTCAIASAAECENATSLSLMIDSLLATYDRESPP---DSKIVVNLTLHLRHAN 220 I++L FL+ A+A + +I L Y +E P +S N+T+ L Sbjct: 10 IVVLHFLMGLAMAQQKQ---------LIKYLFRDYHKELRPVKDESSGPTNVTVQLYFKQ 60 Query: 221 IR---ESESTVRILADLQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLLNAAATT 388 I+ E++ + + ++ W D+ L+WN ++G + V SE +W+PD+++ N A Sbjct: 61 IQKVHENDQIITLYCWIEEYWQDEFLTWNPSDFGNIKSLHVPSEMIWKPDLLVYNNANMN 120 Query: 389 AGDYALR--ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEM 556 + ++ ++ + G +S + + +Q++ +P D Q C S ++ ++ Sbjct: 121 IKENEMQTNVQIEHTGKISLFRAIITDITCDLQMEKFPYDQQICFIMLASWSYDGSQI 178 >UniRef50_A7S2P0 Cluster: Predicted protein; n=4; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 541 Score = 54.4 bits (125), Expect = 4e-06 Identities = 37/174 (21%), Positives = 80/174 (45%), Gaps = 13/174 (7%) Frame = +2 Query: 128 MIDSLLATYDRESPP----DSKIVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLS 292 ++ + +YD + P + V L L L ++ E + + ++ W + ++ Sbjct: 72 LLADVFGSYDNKLRPVLSKTHNVTVKLGLTLNQIMDVIEKFELLSVSLYVRQKWENPLVA 131 Query: 293 WNAGEWGCSTWL-VSSERLWRPDVVLLNAAAT----TAGDYALRARVSNNGSVSWIKRLD 457 WN E+G + + LW+PD+ L N A + + + + +V+ +G+ +W+ Sbjct: 132 WNKSEYGGIVQVNLDPSTLWKPDIYLYNNADSGYDGSLYGFTAKIKVNYSGTNTWLAPKI 191 Query: 458 ISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDK---RIYSMFESGAWD 610 +T + + +P D Q C KFGS ++++ +D ++ I ++G WD Sbjct: 192 FTTSCKINVKYFPFDQQECRLKFGSWTYDANSVDIFPEEDQASIKGYQKNGEWD 245 >UniRef50_Q86YW4 Cluster: Ligand-gated ion channel subunit; n=10; Theria|Rep: Ligand-gated ion channel subunit - Homo sapiens (Human) Length = 411 Score = 54.4 bits (125), Expect = 4e-06 Identities = 28/101 (27%), Positives = 49/101 (48%) Frame = +2 Query: 260 LQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVS 439 L+++W+D RL+WN + E LW P + +L A D + +ARV +G V Sbjct: 86 LRLSWLDTRLAWNTSAHPRHAITLPWESLWTPRLTILEALWVDWRDQSPQARVDQDGHVK 145 Query: 440 WIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDF 562 L T + +L ++P D C+ F + + + E++F Sbjct: 146 LNLALTTETNCNFELLHFPRDHSNCSLSFYALSNTAMELEF 186 >UniRef50_P18505 Cluster: Gamma-aminobutyric acid receptor subunit beta-1 precursor (GABA(A) receptor subunit beta-1); n=104; Euteleostomi|Rep: Gamma-aminobutyric acid receptor subunit beta-1 precursor (GABA(A) receptor subunit beta-1) - Homo sapiens (Human) Length = 474 Score = 54.4 bits (125), Expect = 4e-06 Identities = 42/180 (23%), Positives = 79/180 (43%), Gaps = 9/180 (5%) Frame = +2 Query: 50 IILLPFLLT--CAIASAAECENATSLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRH 214 ++ P ++T C S E N + + +D LL YD PD + V + + + Sbjct: 12 LLSFPVMITMVCCAHSTNEPSNMSYVKETVDRLLKGYDIRLRPDFGGPPVDVGMRIDVAS 71 Query: 215 AN-IRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTA 391 + + E + Q +W DKRLS++ + +++LW PD LN + Sbjct: 72 IDMVSEVNMDYTLTMYFQQSWKDKRLSYSGIPLNLTLDNRVADQLWVPDTYFLNDKKSFV 131 Query: 392 GDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDF 562 ++ R+ +G+V + R+ + M L +P D Q CT + S + +D+++F Sbjct: 132 HGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEF 191 >UniRef50_Q6Q069 Cluster: Neuronal nicotinic acetylcholine Apisa7-2 subunit; n=3; Apis mellifera|Rep: Neuronal nicotinic acetylcholine Apisa7-2 subunit - Apis mellifera (Honeybee) Length = 461 Score = 54.0 bits (124), Expect = 5e-06 Identities = 33/129 (25%), Positives = 56/129 (43%), Gaps = 3/129 (2%) Frame = +2 Query: 182 IVVNLTLHLRHANIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPD 358 +V L+LH ++ E + + W D L WNA E+ G V R+WRPD Sbjct: 33 VVFGLSLH-HIIDVDEKNQILTTNCWVTQIWTDHHLKWNASEFAGIRVIRVPYNRVWRPD 91 Query: 359 VVLLNAAATTAGDYALRARV--SNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 532 +L N A + V S+ G V W+ + + ++ +P D Q C K+ S Sbjct: 92 TILYNNADPQYSSAVINTNVIVSHTGEVVWLSHGIFRSSCDIDVEFFPFDEQRCVLKWAS 151 Query: 533 RMHNSDEMD 559 ++ +++ Sbjct: 152 WTYDGYQLE 160 >UniRef50_Q4R170 Cluster: Putative uncharacterized protein; n=1; Caenorhabditis elegans|Rep: Putative uncharacterized protein - Caenorhabditis elegans Length = 404 Score = 54.0 bits (124), Expect = 5e-06 Identities = 33/136 (24%), Positives = 61/136 (44%), Gaps = 3/136 (2%) Frame = +2 Query: 167 PPDSKIVVNLTLHLRHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSER 343 PP +I + L++ ++ + E E L D + +W D RLSW+ ++G + V + Sbjct: 79 PPRFEITIQLSM-MKLVEVVEPEEKATFLFDYRADWYDTRLSWDPEDYGGINHIYVPRSK 137 Query: 344 LWRPDVVLLNAAATTAGD--YALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCT 517 +W P+ +++ + D Y A + +NGS+ S M + +P D TC+ Sbjct: 138 VWIPETTIVDCSEIKVFDNEYTRYAWLHSNGSIGMYIASVTSVVCQMDVYKFPMDTHTCS 197 Query: 518 FKFGSRMHNSDEMDFV 565 F + +E V Sbjct: 198 VNFLFMTYQLEEFTIV 213 >UniRef50_Q2XWK4 Cluster: Nicotinic acetylcholine receptor subunit type I; n=1; Lymnaea stagnalis|Rep: Nicotinic acetylcholine receptor subunit type I - Lymnaea stagnalis (Great pond snail) Length = 527 Score = 54.0 bits (124), Expect = 5e-06 Identities = 42/178 (23%), Positives = 79/178 (44%), Gaps = 14/178 (7%) Frame = +2 Query: 128 MIDSLLATYDRESPPDSKIVV---NLTLH-----LRHANIRESESTVRILADLQMNWIDK 283 +I SLL Y+R+ ++ N+T+ ++ ++ ES ++ + W D Sbjct: 62 LISSLLKKYERQGKQGRPVINTSDNMTVLFGLSLIQILDVDESNQVLKASMWYRYEWNDM 121 Query: 284 RLSWN-AGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYA-LRARVSNNGSVSWIKRLD 457 L W+ A + + S +W PD++L N A + V NNG + W+ + Sbjct: 122 LLKWDPAMHDDIQSIRIPSSMIWLPDILLYNFADDRLREQRDALCIVQNNGDIQWMPQAI 181 Query: 458 ISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEM--DFVIDKR--IYSMFESGAWDVTD 619 + + S +P D+Q+C KFGS +N ++ +FV + + S WD+ + Sbjct: 182 LRSSCSFDTKYFPFDVQSCWLKFGSWTYNGFKLNVEFVREHSFDLSDYVMSNEWDIIE 239 >UniRef50_Q18556 Cluster: Putative uncharacterized protein acr-9; n=2; Caenorhabditis|Rep: Putative uncharacterized protein acr-9 - Caenorhabditis elegans Length = 534 Score = 54.0 bits (124), Expect = 5e-06 Identities = 33/135 (24%), Positives = 67/135 (49%), Gaps = 5/135 (3%) Frame = +2 Query: 182 IVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL---VSSERLW 349 +VV++ ++L+ ++ E + ++A ++ W D +L W+ E+G + ++ +W Sbjct: 53 LVVSVKIYLQQILDVDEKNQVITLVAWIEYQWTDYKLKWDPSEYGGIKDIRIPGNANAIW 112 Query: 350 RPDVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKF 526 +PDV+L N+A Y + VS G V + + + + +P D Q C KF Sbjct: 113 KPDVLLYNSADENFDSTYPVNYVVSYTGDVLQVPPGILKLSCKIDITYFPFDDQICHLKF 172 Query: 527 GSRMHNSDEMDFVID 571 GS ++ + +D I+ Sbjct: 173 GSWTYSGNFIDLRIN 187 >UniRef50_P31644 Cluster: Gamma-aminobutyric acid receptor subunit alpha-5 precursor (GABA(A) receptor subunit alpha-5); n=86; Euteleostomi|Rep: Gamma-aminobutyric acid receptor subunit alpha-5 precursor (GABA(A) receptor subunit alpha-5) - Homo sapiens (Human) Length = 462 Score = 54.0 bits (124), Expect = 5e-06 Identities = 39/161 (24%), Positives = 73/161 (45%), Gaps = 7/161 (4%) Frame = +2 Query: 104 ENATSLSLMIDSLLATYDRESPPD--SKIV-VNLTLHLRHAN-IRESESTVRILADLQMN 271 +N T + ++D LL YD P +I V +++ + ++E I + + Sbjct: 44 DNITIFTRILDGLLDGYDNRLRPGLGERITQVRTDIYVTSFGPVSDTEMEYTIDVFFRQS 103 Query: 272 WIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSW 442 W D+RL + + + ++W PD N + A + R+ ++G++ + Sbjct: 104 WKDERLRFKGPMQRLPLNNLLASKIWTPDTFFHNGKKSIAHNMTTPNKLLRLEDDGTLLY 163 Query: 443 IKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFV 565 RL IS MQL+++P D C KFGS + + E+ +V Sbjct: 164 TMRLTISAECPMQLEDFPMDAHACPLKFGSYAYPNSEVVYV 204 >UniRef50_UPI00015A4976 Cluster: 5-hydroxytryptamine receptor 3 subunit C; n=2; Danio rerio|Rep: 5-hydroxytryptamine receptor 3 subunit C - Danio rerio Length = 410 Score = 53.6 bits (123), Expect = 6e-06 Identities = 33/157 (21%), Positives = 66/157 (42%), Gaps = 8/157 (5%) Frame = +2 Query: 176 SKIVVNLTLHLRHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRP 355 + + V+LTL+ + E + ++ W + L+W+ E G + E++W P Sbjct: 10 TNVTVDLTLY-GILGVNEKSQVLETYLWVRTRWQIEGLTWDPAECGTKKISLPREKIWFP 68 Query: 356 DVVLLNAAATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSR 535 D+V+ V++ G V + I + + + +P D Q CT+ F S Sbjct: 69 DIVINEFMDENRAPDTYYVYVTSTGQVIDGRPFHIISSCKLDIYTFPFDFQNCTYTFNSY 128 Query: 536 MHNSDEMDFVIDKRIYSMFE--------SGAWDVTDL 622 H+ D++ K + +F+ G W++ D+ Sbjct: 129 KHSRDDVQLFFYKPVKDIFKESLDLMTTKGEWELIDM 165 >UniRef50_UPI00006A0B5C Cluster: Gamma-aminobutyric-acid receptor subunit alpha-3 precursor (GABA(A) receptor subunit alpha-3).; n=2; Xenopus tropicalis|Rep: Gamma-aminobutyric-acid receptor subunit alpha-3 precursor (GABA(A) receptor subunit alpha-3). - Xenopus tropicalis Length = 465 Score = 53.6 bits (123), Expect = 6e-06 Identities = 29/122 (23%), Positives = 61/122 (50%), Gaps = 3/122 (2%) Frame = +2 Query: 206 LRHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAAT 385 ++ N+ E T+ + + +W+D+RL ++ + + ++W PD N + Sbjct: 76 VKQVNMPSLEYTIDVF--FRQSWLDERLKFDGPIRTLPLNNLLASKIWTPDTFFHNGKKS 133 Query: 386 TAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEM 556 A + R+ +NG++ + RL I +M L+++P D+ C KFGS M+ ++++ Sbjct: 134 VAHNMTTPNKLLRLIDNGTLLYTMRLTIHAECTMHLEDFPMDVHACPLKFGSCMYCNEQV 193 Query: 557 DF 562 F Sbjct: 194 SF 195 >UniRef50_Q21645 Cluster: Acetylcholine receptor protein 10; n=2; Caenorhabditis|Rep: Acetylcholine receptor protein 10 - Caenorhabditis elegans Length = 510 Score = 53.6 bits (123), Expect = 6e-06 Identities = 32/113 (28%), Positives = 53/113 (46%), Gaps = 4/113 (3%) Frame = +2 Query: 242 VRILADLQMNWIDKRLSWNAGEWGCST---WLVSSERLWRPDVVLLNAAATTA-GDYALR 409 + + A L+ W+D RL W+ ++ T + ++WRPD++L N+A+ + Sbjct: 12 IEVNAWLKYVWMDYRLQWDPLQYDNITSIRFAGGENQIWRPDILLYNSASEDFDSSFKSN 71 Query: 410 ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVI 568 V N G V+WI M + +P D Q C KFGS ++ +D I Sbjct: 72 EVVYNTGEVNWIPPGIFRASCKMDITYFPFDDQVCYLKFGSWTYHGLALDLSI 124 >UniRef50_O44452 Cluster: Putative uncharacterized protein; n=2; Caenorhabditis|Rep: Putative uncharacterized protein - Caenorhabditis elegans Length = 464 Score = 53.6 bits (123), Expect = 6e-06 Identities = 45/192 (23%), Positives = 83/192 (43%), Gaps = 11/192 (5%) Frame = +2 Query: 128 MIDSLLATYDRESPPDSK----IVVNLTLHLRH-ANIRESESTVRILADLQMNWIDKRLS 292 +I+++ YD+ P ++ ++V++T+ L +RE++ + W D +L+ Sbjct: 44 LIETIQRRYDKRVRPFAESNRPVIVHMTIVLGILTEVRENQQVASFVISHVQKWRDPKLA 103 Query: 293 WNAGEWGCSTWLVSSERL-WRPDVVLLNAAATT--AGDYALRARVSNNGSVSWIKRLDIS 463 WN + T +V L W P + + N+ T D R+ + G V +S Sbjct: 104 WNPADHSGLTQVVMPRSLVWVPKLFIYNSMDTKDMLTDDRYDVRIQHTGHVKVNSPQFVS 163 Query: 464 TPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDF-VIDKRIYSMFESGA-WDVTDLS-SAV 634 T + +D +P D Q C S + + +EMD + S F A W V +++ + Sbjct: 164 TLCRINIDLFPFDTQFCAIALASPLLSVEEMDVNATQPPVDSYFSGNAEWQVMNVTVKQM 223 Query: 635 XSQDRGEVEARV 670 + GE A V Sbjct: 224 KFMEEGEYRAEV 235 >UniRef50_UPI0000F2C37E Cluster: PREDICTED: similar to CHRNG protein; n=1; Monodelphis domestica|Rep: PREDICTED: similar to CHRNG protein - Monodelphis domestica Length = 497 Score = 53.2 bits (122), Expect = 8e-06 Identities = 41/145 (28%), Positives = 68/145 (46%), Gaps = 10/145 (6%) Frame = +2 Query: 128 MIDSLLATYD---RESPPDSKIVVNLTLHLRHANI---RESESTVRILADLQMNWIDKRL 289 +++ L+ Y+ R + DS I+ N+TL L N+ E E + ++M W D RL Sbjct: 27 LLNDLMRNYNPNLRPAEVDSDII-NVTLKLTLTNLISLNEREEALTTNVWIEMQWCDYRL 85 Query: 290 SWNAGEWGCSTWL--VSSERLWRPDVVLLNAAATTAGDYALRARV--SNNGSVSWIKRLD 457 W+ ++ W+ + S +WRPD+VL N + AL V S NG + W+ Sbjct: 86 RWDPRDYE-DVWVLRIPSTMVWRPDIVLENNVDGVF-EVALYCNVLVSPNGCIYWLPPAI 143 Query: 458 ISTPISMQLDNWPNDMQTCTFKFGS 532 + + + +P D Q C+ F S Sbjct: 144 FRSSCPVTVTYFPFDWQNCSLVFQS 168 >UniRef50_Q6TMY3 Cluster: Nicotinic acetylcholine receptor alpha subunit precursor; n=4; Schistosoma|Rep: Nicotinic acetylcholine receptor alpha subunit precursor - Schistosoma haematobium (Blood fluke) Length = 714 Score = 53.2 bits (122), Expect = 8e-06 Identities = 34/140 (24%), Positives = 67/140 (47%), Gaps = 4/140 (2%) Frame = +2 Query: 155 DRESPPDSKIV-VNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL 328 +R S D++ + V++ L ++ E + + + + W D WN E+G T L Sbjct: 47 ERPSANDTETLNVSVKFFLNQVMDVDEKNQVLTTIIWMDLIWNDYHFLWNPKEFGNITTL 106 Query: 329 -VSSERLWRPDVVLLNAAATTAG-DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPND 502 + +WRPD++L N A + + ++G+V W+ + ++ + +P D Sbjct: 107 NLPYTAVWRPDILLYNCADEKFDRTFPTNTIIKHDGTVQWMPPGLFKSTCNIDILWFPFD 166 Query: 503 MQTCTFKFGSRMHNSDEMDF 562 Q+C KFGS + D+++F Sbjct: 167 EQSCILKFGSWTYYGDQINF 186 >UniRef50_A7RFJ2 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 278 Score = 53.2 bits (122), Expect = 8e-06 Identities = 33/130 (25%), Positives = 62/130 (47%), Gaps = 2/130 (1%) Frame = +2 Query: 182 IVVNLTLHLRH-ANIRESESTVRILADLQMNWIDKRLSWNAGEWGCST-WLVSSERLWRP 355 I V + HL A + E E +++ ++ W + L WN E+G T +V + +W P Sbjct: 31 ITVVFSAHLLGLAKVNEKEQSIKTHLWIKEEWYNPFLMWNPEEFGNITEIIVPANMIWVP 90 Query: 356 DVVLLNAAATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSR 535 D++L N +T + + ++ NG+ +W +T + + +P D QTC F S Sbjct: 91 DIILYNKGSTL---FNTKVIIAFNGNNTWRSPAIYNTMCVLDVKYFPFDEQTCDLVFASW 147 Query: 536 MHNSDEMDFV 565 + +++ V Sbjct: 148 TRDISKLNLV 157 >UniRef50_Q14DU4 Cluster: CHRNG protein; n=3; Euarchontoglires|Rep: CHRNG protein - Homo sapiens (Human) Length = 465 Score = 53.2 bits (122), Expect = 8e-06 Identities = 37/135 (27%), Positives = 60/135 (44%), Gaps = 7/135 (5%) Frame = +2 Query: 62 PFLLTCAIASAAECENATSLSLMIDSLLATYDRESPPDSKI--VVNLTLHLRHANI---R 226 P LL +A + ++ L+ YD P + VVN++L L N+ Sbjct: 7 PLLLLLLLAVCLGAQGRNQEERLLADLMQNYDPNLRPAERDSDVVNVSLKLTLTNLISLN 66 Query: 227 ESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAAT-TAGDY 400 E E + ++M W D RL W+ ++ G V S +WRPD+VL N + T + + Sbjct: 67 EREEALTTNVWIEMQWCDYRLRWDPRDYEGLWVLRVPSTMVWRPDIVLENKSQTYSTNEI 126 Query: 401 ALRARVSNNGSVSWI 445 L+ + S+ WI Sbjct: 127 DLQLSQEDGQSIEWI 141 >UniRef50_P02708 Cluster: Acetylcholine receptor subunit alpha precursor; n=142; Coelomata|Rep: Acetylcholine receptor subunit alpha precursor - Homo sapiens (Human) Length = 482 Score = 53.2 bits (122), Expect = 8e-06 Identities = 34/124 (27%), Positives = 62/124 (50%), Gaps = 8/124 (6%) Frame = +2 Query: 272 WIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNGSV 436 W+D L WN ++G + + SE++WRPD+VL N A GD+A+ + + G + Sbjct: 105 WVDYNLKWNPDDYGGVKKIHIPSEKIWRPDLVLYNNA---DGDFAIVKFTKVLLQYTGHI 161 Query: 437 SWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSD--EMDFVIDKRIYSMF-ESGAW 607 +W + + + ++P D Q C+ K G+ ++ ++ D+ S F ESG W Sbjct: 162 TWTPPAIFKSYCEIIVTHFPFDEQNCSMKLGTWTYDGSVVAINPESDQPDLSNFMESGEW 221 Query: 608 DVTD 619 + + Sbjct: 222 VIKE 225 >UniRef50_UPI0000E47329 Cluster: PREDICTED: similar to novel cholinergic receptor, nicotinic, alpha polypeptide protein; n=1; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to novel cholinergic receptor, nicotinic, alpha polypeptide protein - Strongylocentrotus purpuratus Length = 802 Score = 52.8 bits (121), Expect = 1e-05 Identities = 39/153 (25%), Positives = 69/153 (45%), Gaps = 8/153 (5%) Frame = +2 Query: 185 VVNLTLHLRHANIRESESTVRILAD---LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWR 352 ++N++ L + I + + ++L ++ W D RL W E+G T + V +E LW Sbjct: 421 ILNVSFGLSISQIIDLDERNQVLTSKVWVKQQWRDYRLQWEPEEYGGITKIKVPNECLWI 480 Query: 353 PDVVLLNAAATTAG-DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFG 529 PD++L N A A A + G V+W + + + +P D Q C KFG Sbjct: 481 PDILLYNNADGAFDIQSASWAGIDYTGLVTWWPPAVYKSSCQINVAYYPFDEQHCLLKFG 540 Query: 530 SRMHNSDEMD---FVIDKRIYSMFESGAWDVTD 619 S ++ MD + I +++G W + + Sbjct: 541 SWTYDGVVMDLRPISQNAEIRDYWDNGEWQIIE 573 >UniRef50_Q4V4V5 Cluster: IP12579p; n=6; Endopterygota|Rep: IP12579p - Drosophila melanogaster (Fruit fly) Length = 612 Score = 52.4 bits (120), Expect = 1e-05 Identities = 36/147 (24%), Positives = 64/147 (43%), Gaps = 8/147 (5%) Frame = +2 Query: 116 SLSLMIDSLLATYDRESPPDS----KIVVNLTLHLRHAN-IRESESTVRILADLQMNWID 280 ++S+++++LL Y++ P VV + +R + E + + + W D Sbjct: 107 NISMILENLLKRYEQSQLPTHGQGVPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRD 166 Query: 281 KRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKR 451 KRLS+ S + +++WRPD N + + R+ NG + + R Sbjct: 167 KRLSFKGPIKSLSLSIKMLDKIWRPDTYFYNGKHSQIHMITVPNKLLRLDQNGGILYSMR 226 Query: 452 LDISTPISMQLDNWPNDMQTCTFKFGS 532 L I M+L N+P D Q+C GS Sbjct: 227 LTIKATCPMELQNFPMDRQSCPLVIGS 253 >UniRef50_Q2XWK7 Cluster: Nicotinic acetylcholine receptor subunit type F; n=1; Lymnaea stagnalis|Rep: Nicotinic acetylcholine receptor subunit type F - Lymnaea stagnalis (Great pond snail) Length = 488 Score = 52.4 bits (120), Expect = 1e-05 Identities = 29/101 (28%), Positives = 51/101 (50%), Gaps = 2/101 (1%) Frame = +2 Query: 263 QMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYA-LRARVSNNGSV 436 + W D L W+ ++ T + + SE +W PD++L N A + VS++GS+ Sbjct: 97 EYTWSDVLLKWDIEQYDNITDVRIPSEHIWLPDILLYNFADDRLKEQRNALVVVSHDGSL 156 Query: 437 SWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 559 W+ + + + + +P D QTC KFGS +N ++D Sbjct: 157 LWMPQAILRSSCAFNTLYFPFDEQTCVLKFGSWSYNGFKLD 197 >UniRef50_Q0GQQ6 Cluster: Cys-loop ligand-gated ion channel subunit; n=3; Endopterygota|Rep: Cys-loop ligand-gated ion channel subunit - Apis mellifera (Honeybee) Length = 510 Score = 52.4 bits (120), Expect = 1e-05 Identities = 36/147 (24%), Positives = 65/147 (44%), Gaps = 8/147 (5%) Frame = +2 Query: 116 SLSLMIDSLLATYDRESPPD----SKIVVNLTLHLRHAN-IRESESTVRILADLQMNWID 280 ++++++++LL Y+ P + VV + +R + E + + + +W D Sbjct: 36 NITMVLENLLMNYENNQLPTHGKGTPTVVKTNILIRSMGPVSELDMDYSMDCYFRQSWRD 95 Query: 281 KRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKR 451 RLS+ S + ER+WRPD N + + R+S +G + + R Sbjct: 96 SRLSFLGPIKSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRISQDGDILYSMR 155 Query: 452 LDISTPISMQLDNWPNDMQTCTFKFGS 532 L I M+L N+P D Q+C GS Sbjct: 156 LTIKAKCPMELRNFPMDRQSCPLILGS 182 >UniRef50_A7RND6 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 254 Score = 52.0 bits (119), Expect = 2e-05 Identities = 31/119 (26%), Positives = 58/119 (48%), Gaps = 2/119 (1%) Frame = +2 Query: 272 WIDKRLSWNAGEWGCSTWLVSS-ERLWRPDVVLLNAAATTAGDYALRARVSNNGSVSWIK 448 W D RL+WN E+G ++L +++W PD++L A G RA +++ G V + Sbjct: 3 WKDPRLTWNPTEFGNISYLTMKVDKIWSPDMML--TLADIPGSLEFRAIITHEGLVKIFQ 60 Query: 449 RLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDKRIYSMFES-GAWDVTDL 622 IST + + +P D TC + G N+ ++ + I + + + W+++ L Sbjct: 61 PTSISTTCEVNIAFYPFDEHTCFIEIGPWSMNTAAVNVISMGLILTDYSTHNEWNLSPL 119 >UniRef50_Q4RLA7 Cluster: Chromosome 21 SCAF15022, whole genome shotgun sequence; n=5; Clupeocephala|Rep: Chromosome 21 SCAF15022, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 592 Score = 51.6 bits (118), Expect = 3e-05 Identities = 30/121 (24%), Positives = 58/121 (47%), Gaps = 3/121 (2%) Frame = +2 Query: 260 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATT-AGDYALRARVSNNGS 433 L+M+W D L WN E G +++++W PD++L N+A + V+++G Sbjct: 96 LRMSWFDHYLQWNQSEHPGVKNLRFTTDQIWTPDILLYNSADDDFDSTFKTNVLVNSSGY 155 Query: 434 VSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDKR-IYSMFESGAWD 610 + + ++ + +P D+Q C KFGS ++ +D ++ I +G WD Sbjct: 156 AEYQPPGIFMSTCNVDVRWFPFDIQRCELKFGSWTYDGWLLDLQMNNADISGYMPNGEWD 215 Query: 611 V 613 + Sbjct: 216 L 216 >UniRef50_P46098 Cluster: 5-hydroxytryptamine receptor 3 precursor; n=50; Tetrapoda|Rep: 5-hydroxytryptamine receptor 3 precursor - Homo sapiens (Human) Length = 478 Score = 51.6 bits (118), Expect = 3e-05 Identities = 39/175 (22%), Positives = 74/175 (42%), Gaps = 6/175 (3%) Frame = +2 Query: 53 ILLPFLLTCAIASAAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHL---RHA 217 +LLP LL A + +L + D LL Y + P D + +++ + Sbjct: 12 LLLPTLLAQGEARRSRNTTRPALLRLSDYLLTNYRKGVRPVRDWRKPTTVSIDVIVYAIL 71 Query: 218 NIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAG 394 N+ E + + W D+ L WN ++ T L + ++ +W PD+++ Sbjct: 72 NVDEKNQVLTTYIWYRQYWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKS 131 Query: 395 DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 559 + + G V K L + T S+ + N+P D+Q C+ F S +H +++ Sbjct: 132 PNIPYVYIRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLHTIQDIN 186 >UniRef50_UPI0000E48474 Cluster: PREDICTED: similar to nicotinic acetylcholine receptor subunit type G, partial; n=1; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to nicotinic acetylcholine receptor subunit type G, partial - Strongylocentrotus purpuratus Length = 452 Score = 51.2 bits (117), Expect = 3e-05 Identities = 33/117 (28%), Positives = 56/117 (47%), Gaps = 7/117 (5%) Frame = +2 Query: 227 ESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYA 403 E + I ++ +W D++L W+ + G + + +W PDV L + A + DY Sbjct: 2 ERNQVLTINVWIEQHWDDEKLVWDPDAYEGIEILRIPATEIWLPDVTLYDNA--DSNDYV 59 Query: 404 LRARVSN-----NGSVS-WIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEM 556 +R SN +G V W K + + + + +P D Q C+ KFGS +NS +M Sbjct: 60 AHSRQSNALVNADGRVDLWSKPALVKSTCKIDVKFFPFDEQMCSMKFGSWTYNSFQM 116 >UniRef50_Q7ZTN5 Cluster: MGC52789 protein; n=1; Xenopus laevis|Rep: MGC52789 protein - Xenopus laevis (African clawed frog) Length = 459 Score = 51.2 bits (117), Expect = 3e-05 Identities = 45/179 (25%), Positives = 78/179 (43%), Gaps = 13/179 (7%) Frame = +2 Query: 176 SKIVVNLTLHLRHANIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWR 352 S I +++TL+ A + S T+ L + W ++ +SWN + + E LW+ Sbjct: 53 SHIYIDITLYTI-AKLDTSTQTLTSFVWLTLEWTNEYISWNPNNFCDMKEFNTLGESLWK 111 Query: 353 PDVVLLNAAATTAGDYALRA-RVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFG 529 PD+ + + V +G V+ K L I + + + +P D QTC+ FG Sbjct: 112 PDLYIYQITEVDDKSPVIPYFTVHYDGKVTLDKPLRILSSCDVNIYKFPFDTQTCSLTFG 171 Query: 530 S--------RMH---NSDEMDFVIDKRIYSMFESGAWDVTDLSSAVXSQDRGEVEARVA 673 S MH NS E+D DK + G W++ ++ + G+V ++VA Sbjct: 172 SYIYTVKDILMHPKLNSSEVD---DKSFAAFVGKGDWNLINVDVSEFELTDGDVYSKVA 227 >UniRef50_A7SLK4 Cluster: Predicted protein; n=2; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 319 Score = 51.2 bits (117), Expect = 3e-05 Identities = 43/164 (26%), Positives = 81/164 (49%), Gaps = 11/164 (6%) Frame = +2 Query: 122 SLMIDSLLATYDRESPPDSK---IVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRL 289 +L++ +LL YDR P SK +VV + +++ + ++E I L+ W D+RL Sbjct: 23 TLVLKNLLEGYDRRIRPGSKGEPVVVYVDMYVSNIWAMQEMNMDFTIDIYLRQYWRDERL 82 Query: 290 SWNAGEWGCSTWLVS--SERLWRPDVVLLNAAAT-----TAGDYALRARVSNNGSVSWIK 448 + G L S ++++W P L T +Y L+ V +GS+ + Sbjct: 83 QFETQTPGAMLTLSSDINKQIWVPSTYFLATKKAYFHDVTTDNYLLQ--VKPDGSLFYSI 140 Query: 449 RLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDKRI 580 RL I+T + L ++P+D Q+C+ S + S ++ +V ++R+ Sbjct: 141 RLTITTSCRLDLRDFPHDTQSCSLSLESYGYQSTDVLYVWNERL 184 >UniRef50_UPI0000E473D1 Cluster: PREDICTED: similar to neuronal acetylcholine receptor subunit alpha-9 precursor; n=2; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to neuronal acetylcholine receptor subunit alpha-9 precursor - Strongylocentrotus purpuratus Length = 510 Score = 50.8 bits (116), Expect = 4e-05 Identities = 26/110 (23%), Positives = 57/110 (51%), Gaps = 2/110 (1%) Frame = +2 Query: 227 ESESTVRILADLQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLL-NAAATTAGDY 400 E + V++ + +W D+ L W+ ++G T S + +W+PD+ L+ N ++ Sbjct: 140 ERKQHVQLSGWRRQDWRDEFLQWDPDDYGGLETITFSKDGIWKPDITLIENVNQDFINEF 199 Query: 401 ALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSD 550 + V+ +GSV+W + +++ + + +P D QTC + S ++S+ Sbjct: 200 SADVIVTYDGSVTWFTPIILTSACMVGVRYFPFDFQTCQMTYMSWAYDSN 249 >UniRef50_UPI00006602DC Cluster: Homolog of Homo sapiens "5-hydroxytryptamine 3 receptor B subunit; n=1; Takifugu rubripes|Rep: Homolog of Homo sapiens "5-hydroxytryptamine 3 receptor B subunit - Takifugu rubripes Length = 271 Score = 50.8 bits (116), Expect = 4e-05 Identities = 30/95 (31%), Positives = 49/95 (51%), Gaps = 2/95 (2%) Frame = +2 Query: 272 WIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDY-ALRARVSNNGSVSWI 445 W ++ L+WN+ + G VS LW PD+V+ + T+ +Y + A +S+NG V Sbjct: 55 WKNEFLAWNSSVFCGMELLPVSLSLLWVPDIVIREDVSDTSSNYMSPLATLSSNGWVHSS 114 Query: 446 KRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSD 550 R +++ + L +P DMQ C FGS + D Sbjct: 115 LRHVLTSTCKLDLKLFPFDMQICNLSFGSMSFSDD 149 >UniRef50_A7RR86 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 479 Score = 50.8 bits (116), Expect = 4e-05 Identities = 33/153 (21%), Positives = 72/153 (47%), Gaps = 11/153 (7%) Frame = +2 Query: 188 VNLTLHLRHANIRESESTVRILAD---LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRP 355 + + + A + E +S +I+ ++ W + RL W+ ++G T + +S +W P Sbjct: 58 IKVIFDIAFAQLVELDSKNQIMTSYIWVRQFWSNTRLRWDPSKYGGQTSVNLSPHLIWLP 117 Query: 356 DVVLLNAA-ATTAGD---YALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFK 523 D+VL N + T G+ + + + N G++ W + + + + +P D Q C+ Sbjct: 118 DIVLYNNINSNTIGEMFKFDTKVVLHNTGAIEWYAPTLVKSICKIDITYFPFDKQNCSLV 177 Query: 524 FGSRMHNSDEMDFVIDKR---IYSMFESGAWDV 613 FGS + S+ + I ++ + +G W++ Sbjct: 178 FGSWTYTSEFLSLDIKQKEPDLSKYTPNGQWEM 210 >UniRef50_A6XBS1 Cluster: Amorphous calcium carbonate binding protein 1; n=1; Pinctada fucata|Rep: Amorphous calcium carbonate binding protein 1 - Pinctada fucata (Pearl oyster) Length = 240 Score = 50.8 bits (116), Expect = 4e-05 Identities = 48/171 (28%), Positives = 75/171 (43%), Gaps = 7/171 (4%) Frame = +2 Query: 68 LLTCAIASAAECENATSLSLMIDSLLATYDRESPPDSKI-VVNLTLHLRHANIRESEST- 241 +L A+ + + A L ++D R P D VV++ L H + +S+S Sbjct: 17 VLFSAVVAKCDYPEAKLLKFLLDDYEKLV-RPVPKDGNATVVSMGFSLNHIDDYDSDSME 75 Query: 242 VRILADLQMNWIDKRLSWN--AGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDY--AL 406 ++ A L + W D RL+WN G +G L + +W PDVVLLN + L Sbjct: 76 LKSNAWLSLKWNDPRLTWNKDGGPFGNVKALHLPPSDIWVPDVVLLNGLQPFQPQFPDRL 135 Query: 407 RARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 559 A V + G + I + T + D D TC FKF S ++ E++ Sbjct: 136 TALVKDTGDIYLITPSVLETRCTP--DKADGDKATCRFKFMSWTYDGGEVE 184 >UniRef50_Q99928 Cluster: Gamma-aminobutyric acid receptor subunit gamma-3 precursor (GABA(A) receptor subunit gamma-3); n=106; Euteleostomi|Rep: Gamma-aminobutyric acid receptor subunit gamma-3 precursor (GABA(A) receptor subunit gamma-3) - Homo sapiens (Human) Length = 467 Score = 50.8 bits (116), Expect = 4e-05 Identities = 39/172 (22%), Positives = 73/172 (42%), Gaps = 7/172 (4%) Frame = +2 Query: 113 TSLSLMIDSLLATYDRESPPDSKI---VVNLTLHLRHAN-IRESESTVRILADLQMNWID 280 T ++L+++ LL YD++ PD I V+++ +++ + +I W D Sbjct: 45 TDVTLILNKLLREYDKKLRPDIGIKPTVIDVDIYVNSIGPVSSINMEYQIDIFFAQTWTD 104 Query: 281 KRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKR 451 RL +N+ + +W PD + N+ A R+ N+G + + R Sbjct: 105 SRLRFNSTMKILTLNSNMVGLIWIPDTIFRNSKTAEAHWITTPNQLLRIWNDGKILYTLR 164 Query: 452 LDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDKRIYSMFESGAW 607 L I+ +QL N+P D +C F S + +EM + K + +W Sbjct: 165 LTINAECQLQLHNFPMDEHSCPLIFSSYGYPKEEMIYRWRKNSVEAADQKSW 216 >UniRef50_P34903 Cluster: Gamma-aminobutyric acid receptor subunit alpha-3 precursor (GABA(A) receptor subunit alpha-3); n=94; Euteleostomi|Rep: Gamma-aminobutyric acid receptor subunit alpha-3 precursor (GABA(A) receptor subunit alpha-3) - Homo sapiens (Human) Length = 492 Score = 50.8 bits (116), Expect = 4e-05 Identities = 36/158 (22%), Positives = 70/158 (44%), Gaps = 7/158 (4%) Frame = +2 Query: 104 ENATSLSLMIDSLLATYDRESPP---DSKIVVNLTLHLRHAN-IRESESTVRILADLQMN 271 +N T + ++D LL YD P D+ V +++ + +++ I + Sbjct: 62 DNITIFTRILDRLLDGYDNRLRPGLGDAVTEVKTDIYVTSFGPVSDTDMEYTIDVFFRQT 121 Query: 272 WIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSW 442 W D+RL ++ + + ++W PD N + A + R+ +NG++ + Sbjct: 122 WHDERLKFDGPMKILPLNNLLASKIWTPDTFFHNGKKSVAHNMTTPNKLLRLVDNGTLLY 181 Query: 443 IKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEM 556 RL I M L+++P D+ C KFGS + + E+ Sbjct: 182 TMRLTIHAECPMHLEDFPMDVHACPLKFGSYAYTTAEV 219 >UniRef50_UPI0000E47720 Cluster: PREDICTED: similar to alpha-9 nicotinic acetylcholine receptor subunit precursor; n=4; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to alpha-9 nicotinic acetylcholine receptor subunit precursor - Strongylocentrotus purpuratus Length = 572 Score = 50.4 bits (115), Expect = 6e-05 Identities = 31/118 (26%), Positives = 52/118 (44%), Gaps = 6/118 (5%) Frame = +2 Query: 272 WIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYA-LRARVSNNGSVSWI 445 W D+ + W+ ++ G V +W PD+ L YA VS+NG++ W Sbjct: 193 WTDENMIWDPLDFDGVDYVTVKKNDVWLPDICLYQNVVKDFISYADTYIVVSSNGTMDWY 252 Query: 446 KRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVI----DKRIYSMFESGAW 607 + I+T + + +P D+Q C FG N+D + F I D + ++G W Sbjct: 253 VPVIIATSCPIDITYFPYDVQHCNLTFGPWTLNTDRVRFQISTDDDANVNLFHKNGVW 310 >UniRef50_Q9VPQ8 Cluster: CG11822-PA, isoform A (Nicotinic acetylcholine receptor beta subunit) (Nicotinic acetylcholine receptor beta 3 (Dbeta3) subunit); n=4; Sophophora|Rep: CG11822-PA, isoform A (Nicotinic acetylcholine receptor beta subunit) (Nicotinic acetylcholine receptor beta 3 (Dbeta3) subunit) - Drosophila melanogaster (Fruit fly) Length = 441 Score = 50.4 bits (115), Expect = 6e-05 Identities = 34/147 (23%), Positives = 62/147 (42%), Gaps = 5/147 (3%) Frame = +2 Query: 107 NATSLSLMIDSLLATYDRESPP---DSKIVVNLTLHLRHANIRESESTVRILADLQMNWI 277 N +L + L YD + P + V+L + + + +I E + L + W Sbjct: 47 NVKALDRLHAGLFTNYDSDVQPVFQGTPTNVSLEMVVTYIDIDELNGKLTTHCWLNLRWR 106 Query: 278 DKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYA-LRARVSNNGSVSWIKR 451 D+ W ++ T + + S +W P + L N G A + +S++G W+ Sbjct: 107 DEERVWQPSQYDNITQITLKSSEVWTPQITLFNG--DEGGLMAETQVTLSHDGHFRWMPP 164 Query: 452 LDISTPISMQLDNWPNDMQTCTFKFGS 532 + + + NWP+D Q+C K GS Sbjct: 165 AVYTAYCELNMLNWPHDKQSCKLKIGS 191 >UniRef50_Q9GQU9 Cluster: Nicotinic acetylcholine receptor-like subunit ACR-12; n=2; Caenorhabditis|Rep: Nicotinic acetylcholine receptor-like subunit ACR-12 - Caenorhabditis elegans Length = 573 Score = 50.4 bits (115), Expect = 6e-05 Identities = 33/120 (27%), Positives = 55/120 (45%), Gaps = 2/120 (1%) Frame = +2 Query: 206 LRHANIRESESTVRILADLQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLLNAAA 382 +R ++ E + L+M W D +L+W ++G T + S+ +W PD+VL N AA Sbjct: 72 IRIIDVDEKNQVLTTNLWLEMKWNDAKLTWTPEKYGGLKTLHIPSDFIWTPDLVLYNNAA 131 Query: 383 TTAGDYALR-ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 559 L A V+ G+V W + + + +P D Q C KFG+ + +D Sbjct: 132 GDPDITILTDALVTFEGNVYWQPPAIYKSFCPIDVTWFPYDSQKCEMKFGTWTYTGRYVD 191 >UniRef50_Q621V5 Cluster: Putative uncharacterized protein CBG02331; n=1; Caenorhabditis briggsae|Rep: Putative uncharacterized protein CBG02331 - Caenorhabditis briggsae Length = 472 Score = 50.4 bits (115), Expect = 6e-05 Identities = 44/151 (29%), Positives = 71/151 (47%), Gaps = 9/151 (5%) Frame = +2 Query: 131 IDSLLATYDRESPPDSKIVVNLTLHLRHANIRE-SESTVRILADLQMN--WIDKRLSWNA 301 + LL YD+ P + V +++ L +I SE + +AD+ + W D RL + Sbjct: 75 LSDLLQDYDKTMVPSNNSV-QVSVELTVQDISSISEISSSFIADVWFSQVWEDPRLEYRN 133 Query: 302 GEWGCSTWLVS--SERLWRPDVVLLNAAATTAGDYA---LRARVSNNGSVSWIK-RLDIS 463 + L S SERLW P+V +N+ +T + + NG+V W+ R+ +S Sbjct: 134 ISCKTNLSLDSYVSERLWTPNVCFVNSKSTQVHKSPASNILLIIYPNGTV-WLNYRVQVS 192 Query: 464 TPISMQLDNWPNDMQTCTFKFGSRMHNSDEM 556 P S +L +P D Q C F S +N E+ Sbjct: 193 APCSFELSRFPIDAQECHLVFESYSYNIAEV 223 >UniRef50_UPI0000660F16 Cluster: Homolog of Homo sapiens "Splice Isoform 2 of 5-hydroxytryptamine 3 receptor precursor; n=1; Takifugu rubripes|Rep: Homolog of Homo sapiens "Splice Isoform 2 of 5-hydroxytryptamine 3 receptor precursor - Takifugu rubripes Length = 430 Score = 50.0 bits (114), Expect = 8e-05 Identities = 36/142 (25%), Positives = 59/142 (41%), Gaps = 10/142 (7%) Frame = +2 Query: 260 LQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVS 439 L W LSW+ E G V E +W PDV + + N G V Sbjct: 7 LMQEWDIDGLSWDVQECGTEKVSVLRESIWVPDVHIAEFMEENKSQRTPFVYLYNTGGVF 66 Query: 440 WIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEM---------DFVIDKRIYSMF 592 + + + + + + +P D+Q CT FGS +H + E+ D + + R +F Sbjct: 67 DDRPIRVVSSCKLDIYTFPFDIQNCTLTFGSYVHFASEIRMSQGSTAEDILQESR--EVF 124 Query: 593 E-SGAWDVTDLSSAVXSQDRGE 655 E +G WD+ D+ + + GE Sbjct: 125 ETNGEWDLADIQAVPFTLSLGE 146 >UniRef50_Q4RR58 Cluster: Chromosome 14 SCAF15003, whole genome shotgun sequence; n=1; Tetraodon nigroviridis|Rep: Chromosome 14 SCAF15003, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 470 Score = 50.0 bits (114), Expect = 8e-05 Identities = 36/141 (25%), Positives = 65/141 (46%), Gaps = 7/141 (4%) Frame = +2 Query: 128 MIDSLLATYDRESPPDSKI--VVNLTLHLRHANIRESESTVRILAD---LQMNWIDKRLS 292 + L A Y++ S P + VV + L A + + + +++ L+ W D +L Sbjct: 7 LFKKLFAGYNKYSRPVPNVTDVVIVKFGLSIAQLIDVDEKNQMMTTNVWLKQEWNDYKLR 66 Query: 293 WNAGEWGCSTWL-VSSERLWRPDVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDIST 466 W ++ T + V SE +W PD+VL N A A + +A + +NG + W+ ++ Sbjct: 67 WRPSDYDNVTSIRVPSELIWVPDIVLYNNADGEFAVTHMTKAHLFHNGKIRWVPPAIYNS 126 Query: 467 PISMQLDNWPNDMQTCTFKFG 529 + + +P D T KFG Sbjct: 127 SCIIDVTFFPFDQHTARCKFG 147 >UniRef50_Q6BET0 Cluster: Putative uncharacterized protein; n=2; Caenorhabditis|Rep: Putative uncharacterized protein - Caenorhabditis elegans Length = 536 Score = 50.0 bits (114), Expect = 8e-05 Identities = 33/163 (20%), Positives = 71/163 (43%), Gaps = 12/163 (7%) Frame = +2 Query: 110 ATSLSLMIDSLLATYDRESPPD------SKIVVNLTLHLRHANIRESESTVRILADLQMN 271 A +++ +++++L YD+ P +K+ ++L + + + +T + Sbjct: 59 AQNVTHLLNNVLKNYDQHFRPGFNSGKPTKVYIDLFIRTM-GPVSDLFNTYSFNCYFRQK 117 Query: 272 WIDKRLSWNAGEWG---CSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGS 433 W D RL +N G S + +++W+PD N A + R+ +G+ Sbjct: 118 WTDDRLHFNNSGIGFRQLSLSMAMLDKIWKPDTYFWNGAGSYVHGITTSNRLVRLEPDGT 177 Query: 434 VSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDF 562 + + R+ + M + +P D Q C GS ++SDE+ + Sbjct: 178 ILYSSRITVKAKCQMDMSRYPLDKQACRLVIGSYAYSSDEVQY 220 >UniRef50_UPI000069FF34 Cluster: UPI000069FF34 related cluster; n=1; Xenopus tropicalis|Rep: UPI000069FF34 UniRef100 entry - Xenopus tropicalis Length = 356 Score = 49.6 bits (113), Expect = 1e-04 Identities = 27/91 (29%), Positives = 44/91 (48%), Gaps = 1/91 (1%) Frame = +2 Query: 260 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 436 L W ++ LSW++ E+ G S + +W PD+ + + D L + NNG+V Sbjct: 3 LLQTWENQLLSWDSEEFCGISRVSIPESTIWIPDIYISETIEDNSLD-VLYVHLYNNGTV 61 Query: 437 SWIKRLDISTPISMQLDNWPNDMQTCTFKFG 529 K L++ T ++ L +P D Q C FG Sbjct: 62 QRTKTLNVMTTCTLDLYKFPFDEQKCNLTFG 92 >UniRef50_Q95Y52 Cluster: Putative uncharacterized protein; n=2; Caenorhabditis|Rep: Putative uncharacterized protein - Caenorhabditis elegans Length = 508 Score = 49.6 bits (113), Expect = 1e-04 Identities = 40/184 (21%), Positives = 85/184 (46%), Gaps = 11/184 (5%) Frame = +2 Query: 104 ENATSLSLMIDSLLATYDRESPPDSKIVVNLTLHLRH-ANIRESESTVRILADLQMNWID 280 +N + S ++ ++++ Y+R P ++ V + + ++ I + S ++ + W D Sbjct: 61 KNCANDSFILGTIMSNYNRHKIPGGQVDVEVEVWVQEITTISDITSDFQLDIYIYETWYD 120 Query: 281 KRLSW---NAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYA---LRARVSNNGSVSW 442 L++ N ++ S V E+LW P+ +N+ + + NG+V Sbjct: 121 PALNYAFMNPCKYNLSLNSVLLEKLWTPNSCFINSKTADIHKSPFPNIFLMIYANGTVWT 180 Query: 443 IKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDE--MDFVID--KRIYSMFESGAWD 610 RL + P M L +P D TC+ F S +N+DE MD+ ++ +++ E ++ Sbjct: 181 NYRLKLQGPCIMDLTKFPFDNVTCSLTFESFNYNTDEVKMDWSVNGVQKMRDKMELADYE 240 Query: 611 VTDL 622 + D+ Sbjct: 241 LVDI 244 >UniRef50_Q9W288 Cluster: CG6698-PA; n=4; Sophophora|Rep: CG6698-PA - Drosophila melanogaster (Fruit fly) Length = 585 Score = 49.2 bits (112), Expect = 1e-04 Identities = 31/143 (21%), Positives = 63/143 (44%), Gaps = 4/143 (2%) Frame = +2 Query: 113 TSLSLMIDSLLATYDRESPPDSKIVVNLTLHLRHANIRESESTVRILADLQMNWIDKRLS 292 T ++ L + S P + ++ R ++ S ++ + M+W D RL Sbjct: 214 TKTEKLLSHLNIQAENASMPANLSSISFHFQTRSLAYEQTSSLLQTRMHMMMHWRDSRLV 273 Query: 293 WNAGEWG-CSTWLVSSERLWRPDVVLLNAAATTAGD--YALRARVSNNGSVS-WIKRLDI 460 W ++G ++ R+W+P + +LN A + G + V NGS++ + + L + Sbjct: 274 WKPEDFGSLESFEHPDLRIWKPHMNVLNGALQSMGQVLQSYELMVYANGSITLYAQNLQL 333 Query: 461 STPISMQLDNWPNDMQTCTFKFG 529 ++ NWP++ TC + G Sbjct: 334 ASWCVDSARNWPSERVTCDIELG 356 >UniRef50_A7S2G2 Cluster: Predicted protein; n=2; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 270 Score = 49.2 bits (112), Expect = 1e-04 Identities = 33/133 (24%), Positives = 62/133 (46%), Gaps = 10/133 (7%) Frame = +2 Query: 188 VNLTLHLRHANI---RESESTVRILADLQMNWIDKRLSWNA----GEWGCSTWLVSSERL 346 VN+T+++R ++ RE + + W D RL++N G+ L +++ + Sbjct: 4 VNITVNMRINSVFDVREEAMDYTMRFAFRQKWRDPRLTYNISLTRGQGHPYIQLETADLI 63 Query: 347 WRPDVVLLNAAATTAGDYA---LRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCT 517 W PD +NA + D L R+ +GS+ +++ ++ M L +P D Q C Sbjct: 64 WYPDTFFMNARKSYIHDVTKKNLGIRLFPDGSIYMSQKITVTAECQMDLRKFPMDTQVCV 123 Query: 518 FKFGSRMHNSDEM 556 +F S H + E+ Sbjct: 124 LQFESFFHTAAEI 136 >UniRef50_A7RLM5 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 317 Score = 49.2 bits (112), Expect = 1e-04 Identities = 28/105 (26%), Positives = 50/105 (47%), Gaps = 5/105 (4%) Frame = +2 Query: 260 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAA----TTAGDYALRARVSN 424 L+M W D L WN ++G T + + + +W P V++ N A + R V + Sbjct: 58 LRMGWKDAFLQWNPADYGGVTQINLEASDIWTPPVIIYNQAGDLGESITSSNTPRPVVRS 117 Query: 425 NGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 559 +G+V W+ I + + + +P D Q C FGS ++ ++D Sbjct: 118 DGTVLWMVPTVIKSSCVIDVKYFPFDQQLCKIIFGSWHYDVSKLD 162 >UniRef50_P45963 Cluster: Acetylcholine receptor subunit alpha-type acr-7 precursor; n=2; Caenorhabditis|Rep: Acetylcholine receptor subunit alpha-type acr-7 precursor - Caenorhabditis elegans Length = 538 Score = 49.2 bits (112), Expect = 1e-04 Identities = 32/142 (22%), Positives = 63/142 (44%), Gaps = 8/142 (5%) Frame = +2 Query: 170 PDSKIVVNLTLHLRHANIRESE-STVRILADLQMNWIDKRLSWNAGEWG--CSTWLVSSE 340 P + V + + ++ + +++ + + A L+ W D RL WN ++ S + Sbjct: 52 PKKALTVTMKVFIQQVLLVDAKHQMIEVNAWLKYIWTDFRLRWNPLDYENITSVRFQGED 111 Query: 341 RLWRPDVVLLNAAATTAGD-----YALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDM 505 ++W+PD++L N + Y A ++G ++WI M + +P D Sbjct: 112 QIWQPDILLYNRYIEDEQESFDITYKTNAVAYSDGVINWIPPGIFKLSCKMDITLFPFDE 171 Query: 506 QTCTFKFGSRMHNSDEMDFVID 571 Q C KFGS ++ +D +D Sbjct: 172 QICFMKFGSWTYHGFALDLRLD 193 >UniRef50_UPI0000E49D12 Cluster: PREDICTED: similar to acetylcholin receptor alpha subunit 1A; n=2; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to acetylcholin receptor alpha subunit 1A - Strongylocentrotus purpuratus Length = 462 Score = 48.8 bits (111), Expect = 2e-04 Identities = 34/143 (23%), Positives = 65/143 (45%), Gaps = 8/143 (5%) Frame = +2 Query: 227 ESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYA 403 E + + ++++M W D+ L W+ EW G ++ + +W+PD L A Sbjct: 85 EHSQHITLRSNMKMTWRDEYLQWDPSEWDGITSVTLRPSDIWKPDFDLEQNVERVHFIVA 144 Query: 404 LRARVSN-NGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKF------GSRMHNSDEMDF 562 +++ G+V WI + +T + + +P D+Q C F S+M E D Sbjct: 145 DTYVIADYTGTVRWIFPVITTTACKINIVYFPYDVQQCNVTFYPWTLDNSQMRLLAEDDD 204 Query: 563 VIDKRIYSMFESGAWDVTDLSSA 631 +++Y +G WD+T+ +A Sbjct: 205 DAHQQMY--IRNGVWDLTNFQAA 225 >UniRef50_UPI000069F132 Cluster: 5-hydroxytryptamine receptor 3 subunit D; n=3; Euteleostomi|Rep: 5-hydroxytryptamine receptor 3 subunit D - Xenopus tropicalis Length = 415 Score = 48.8 bits (111), Expect = 2e-04 Identities = 29/118 (24%), Positives = 53/118 (44%), Gaps = 2/118 (1%) Frame = +2 Query: 185 VVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPD 358 VVN+++ + + E + + L M W ++ W G V +E +W PD Sbjct: 11 VVNISITVYAILGVNEKDQLLTSFLWLTMVWFNEFAEWEPALCGGVQNISVPAEEMWIPD 70 Query: 359 VVLLNAAATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 532 + +L + V +NG V ++K L + + ++ + +P D+Q CT FGS Sbjct: 71 IFVLQFVDEDKSPHLPYLLVDHNGRVRFLKPLRVVSSCNLSIFRFPFDIQNCTLTFGS 128 >UniRef50_UPI000065F0EC Cluster: Homolog of Homo sapiens "5-hydroxytryptamine receptor 3 subunit C; n=2; Takifugu rubripes|Rep: Homolog of Homo sapiens "5-hydroxytryptamine receptor 3 subunit C - Takifugu rubripes Length = 411 Score = 48.8 bits (111), Expect = 2e-04 Identities = 36/148 (24%), Positives = 63/148 (42%), Gaps = 10/148 (6%) Frame = +2 Query: 242 VRILADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVS 421 + ++ L + W LSW+ E G V E +W PDV + + Sbjct: 45 ITVVGVLGVEWDIDGLSWDVQECGTEKVSVLRESIWVPDVHIAEFMEEDQSPRTPFVYLY 104 Query: 422 NNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEM---------DFVIDK 574 N G V + + + + + + +P D+Q CT FGS +H + E+ D + + Sbjct: 105 NTGGVFDDRPIRVVSSCKLDIYTFPFDIQNCTLTFGSYVHFASEIRMSQGSTAEDILQES 164 Query: 575 RIYSMFE-SGAWDVTDLSSAVXSQDRGE 655 R +FE +G WD+ D+ A + G+ Sbjct: 165 R--EVFETNGEWDLADIEIAPVTLSLGK 190 >UniRef50_Q20828 Cluster: Putative uncharacterized protein; n=2; Caenorhabditis|Rep: Putative uncharacterized protein - Caenorhabditis elegans Length = 517 Score = 48.8 bits (111), Expect = 2e-04 Identities = 42/173 (24%), Positives = 80/173 (46%), Gaps = 11/173 (6%) Frame = +2 Query: 74 TCAIASAAEC--ENATSLSLMIDSLLATYDR-ESPPDSKIVVNLTLHLRHAN-IRESEST 241 T A+A+ E E TS +I+ LL Y +P +S ++V + + ++ N + E S Sbjct: 49 TNAVAATDEDGEELCTSDKTIIEKLLNNYKSFRTPSESGVIVWIEVWVQEVNSVNEITSD 108 Query: 242 VRILADLQMNWIDKRLSW---NAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR- 409 + + W+D L + N ++ S +++W+P+ V +N+ + + Sbjct: 109 FDMDIYVTELWMDSALRYEHLNPCKYNLSLNSEILDQIWKPNTVFINSKSANIHKSPFKN 168 Query: 410 --ARVSNNGSVSWIK-RLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 559 + NG+V W+ R+ + P SM +P D Q+C S +N+ E+D Sbjct: 169 VFLMIYPNGTV-WVNYRVQVKGPCSMDFSAFPMDQQSCHLTLESFSYNNQEVD 220 >UniRef50_A7S9T8 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 390 Score = 48.8 bits (111), Expect = 2e-04 Identities = 29/105 (27%), Positives = 46/105 (43%), Gaps = 5/105 (4%) Frame = +2 Query: 260 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAA--ATTAGDYALRARVS--N 424 ++ W D L W+ + G T + V LW+PD+VL N Y +V + Sbjct: 13 VRQTWTDAWLKWDPAKHGGITAINVDPSFLWKPDMVLYNNVNDEDRGEQYLFNTKVIIYS 72 Query: 425 NGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 559 G + W + T + + +P D QTC FGS +N ++D Sbjct: 73 TGDIEWYSPNILKTHCKIDIQYFPFDTQTCKLTFGSWTYNGLKID 117 >UniRef50_A7S6R3 Cluster: Predicted protein; n=3; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 409 Score = 48.8 bits (111), Expect = 2e-04 Identities = 43/161 (26%), Positives = 74/161 (45%), Gaps = 5/161 (3%) Frame = +2 Query: 95 AECENATSLS-LMIDSLLATYDRESPPDS---KIVVNLTLHLR-HANIRESESTVRILAD 259 +E NAT L M+ S + YDR++ P++ + V L++ ++ +I+E+ Sbjct: 37 SEIINATRLQERMLSS--SNYDRKARPNAGKEPLDVYLSIGVQAFTSIKETNMEFTTSLF 94 Query: 260 LQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVS 439 L+ W D RL+ + S V ++WRPD + N A +S G V Sbjct: 95 LRQEWTDIRLAHGL-DGTISLGGVEVNQIWRPDTYINNNNDYELHVENQLALISKYGDVY 153 Query: 440 WIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDF 562 + R+ + M L N+P D+Q C+ F S + +D + F Sbjct: 154 FSARMLVRASCQMYLQNFPMDVQKCSLVFESFAYTNDHVAF 194 >UniRef50_P41849 Cluster: Uncharacterized glycine receptor-like protein T20B12.9; n=2; Caenorhabditis|Rep: Uncharacterized glycine receptor-like protein T20B12.9 - Caenorhabditis elegans Length = 476 Score = 48.8 bits (111), Expect = 2e-04 Identities = 46/164 (28%), Positives = 78/164 (47%), Gaps = 11/164 (6%) Frame = +2 Query: 98 ECENATSLSLMIDSLLATYDRESPPDSKIVVNLTLHLRHANIRE-SESTVRILADLQMN- 271 E + +L +ID+LL YD P+++ VN+T+ L + SE T D+ + Sbjct: 9 EFNSRINLGKLIDTLLTDYDTHLLPEAE-GVNVTIELHVQGVSGISEITGDFSLDVMYSE 67 Query: 272 -WIDKRLSWNAGEWGCSTWL---VSS--ERLWRPDVVLLNAAATTAGDYALRAR---VSN 424 W D RLS+ C+T + VS +++W PD ++N+ +++ + Sbjct: 68 IWQDPRLSFKHLNV-CATNITLKVSDFRKKIWTPDTCIINSKSSSIHSSPSENTFVILYE 126 Query: 425 NGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEM 556 NG V RL++ TP S+ L +P D +C S N+DE+ Sbjct: 127 NGLVWSNFRLNVKTPCSVNLKMFPFDSLSCEIVLESYSFNTDEV 170 >UniRef50_UPI00003CEF8B Cluster: R03E1.3; n=1; Caenorhabditis elegans|Rep: R03E1.3 - Caenorhabditis elegans Length = 467 Score = 48.4 bits (110), Expect = 2e-04 Identities = 29/111 (26%), Positives = 47/111 (42%), Gaps = 4/111 (3%) Frame = +2 Query: 188 VNLTLHLRHAN-IRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVV 364 VN+ L + H + E E T + + WID+ + W+A + + +S+ LW+P + Sbjct: 54 VNVFLSIAHVEKVDEHEQTALVHGHIWATWIDEYMQWDAKKENVTKLTISAHSLWQPALA 113 Query: 365 LLNAAATTAGDY---ALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQ 508 L N+A + A+ A V + G V NWP D Q Sbjct: 114 LYNSARGNSWHLYMGAMPATVYSTGKVWSTGTFSFYVTCQFDFTNWPFDQQ 164 >UniRef50_Q9GUF0 Cluster: Ligand-gated ion channel protein 10; n=3; Caenorhabditis|Rep: Ligand-gated ion channel protein 10 - Caenorhabditis elegans Length = 493 Score = 48.4 bits (110), Expect = 2e-04 Identities = 40/165 (24%), Positives = 73/165 (44%), Gaps = 10/165 (6%) Frame = +2 Query: 92 AAECENATSL----SLMIDSLLATYDRESPP--DSKIVVNLTLHLRHA-NIRESESTVRI 250 A CEN +L S +++ + YDR P ++VN+T+ L ++E++ Sbjct: 57 ALNCENFRTLDNETSAILNDIFVGYDRRVLPFVQGPVLVNMTIVLGILIELKENQQLAAY 116 Query: 251 LADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRA--RVS 421 + W D RLSW+ ++ G +V +W P + + N+ + RA R+ Sbjct: 117 VISHTQRWYDGRLSWDPSKYRGQREVIVPQTMVWIPKLFVYNSLESKDMLTENRADVRLY 176 Query: 422 NNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEM 556 +NG + + +Q +++P D Q C S + N +EM Sbjct: 177 HNGRIKINIPQYVQAICRIQTESFPFDCQFCAVALASPLLNVNEM 221 >UniRef50_Q6U4B6 Cluster: Nicotinic acetylcholine receptor alpha 2 subunit; n=2; Nilaparvata lugens|Rep: Nicotinic acetylcholine receptor alpha 2 subunit - Nilaparvata lugens (Brown planthopper) Length = 590 Score = 48.4 bits (110), Expect = 2e-04 Identities = 56/200 (28%), Positives = 86/200 (43%), Gaps = 24/200 (12%) Frame = +2 Query: 26 CHK-MSTTYIILLPFLLTCAIASAAECENATSLSLMIDSLLATYDRESPPDSK----IVV 190 C K M T +ILL ++ + + A S + LL+ Y+R P + ++ Sbjct: 6 CTKLMRTCPLILLILIILLLLCETVDGAAANPDSKRLGDLLSNYNRLIRPVTNSTDTVLG 65 Query: 191 NLTLHLRHANIRESESTVRILA-----DL--QMNWIDKRLS--WNA-----GEWGCSTWL 328 + L LR + + + S +I+ DL W D + S WN G G ST L Sbjct: 66 SGKLGLRLSQLIDVNSKNQIMGTNVWVDLGHHSEWQDHKSSGFWNPSDDEYGGVGSSTEL 125 Query: 329 -VSSERLWRPDVVLLNAA----ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNW 493 V SE +W PD+VL N A A A +A + G V W + + ++ + Sbjct: 126 AVPSEHIWDPDIVLYNNADGKYAVGGSMTATKAYLHYGGGVWWSPPAIYGSSCEIDVEYF 185 Query: 494 PNDMQTCTFKFGSRMHNSDE 553 P D Q C KFGS ++ D+ Sbjct: 186 PFDEQGCYMKFGSWTYDGDQ 205 >UniRef50_Q2WF65 Cluster: Gaba/glycine receptor family (See gbr) protein 2, isoform a; n=3; Caenorhabditis|Rep: Gaba/glycine receptor family (See gbr) protein 2, isoform a - Caenorhabditis elegans Length = 546 Score = 48.4 bits (110), Expect = 2e-04 Identities = 38/177 (21%), Positives = 73/177 (41%), Gaps = 13/177 (7%) Frame = +2 Query: 65 FLLTCAIASAAECENATSLSLMIDSLL----ATYDRESPP-----DSKIVVNLTLHLRH- 214 FLL + E + + + +D+LL YD +SPP + VV L +++ Sbjct: 8 FLLLYRNSPKVEASRSEPVPIYLDNLLNAGRQVYDNQSPPVQHDKEEVTVVELAMYIEGM 67 Query: 215 ANIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAG 394 ++ R ++ Q W D RL+ N ++W+PDV NA Sbjct: 68 SSFRTQTMDFQLDVYFQQFWRDPRLAHNETRRVLVKDKAVLHKMWKPDVYFANARIAEFH 127 Query: 395 DYA---LRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEM 556 + + +GS+ + R+ + ++ L+ WP D Q C + S + ++++ Sbjct: 128 EVTQPNFLVWIQPDGSILYDTRISMVVVCTLNLEKWPLDSQRCHLRILSYAYTTEQL 184 >UniRef50_A2TM50 Cluster: Nicotinic acetylcholine receptor alpha 4 subunit; n=4; Aphidinae|Rep: Nicotinic acetylcholine receptor alpha 4 subunit - Sitobion avenae (English grain aphid) Length = 532 Score = 48.4 bits (110), Expect = 2e-04 Identities = 47/184 (25%), Positives = 79/184 (42%), Gaps = 14/184 (7%) Frame = +2 Query: 50 IILLPFLLT---CAIA-SAAECENATSLSLMIDSLLATYDRESPPDSKIVVNLTLHLRHA 217 + +LP LL C A + + E + D LL+ Y+R P NLT+ + Sbjct: 4 LFILPLLLPLSYCEFALNNTKFEGNPYKKHLFDDLLSNYNRLIRPVQNHSENLTVWMGLK 63 Query: 218 NIRESESTVRILADLQMNWI-----DKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAA 379 + +E ++ W+ D L W+ ++G L V S+ +W PD+VL N A Sbjct: 64 LTQLTEMNLKSQVMTTSVWLIQKRFDCNLKWDPKDYGGLDKLYVPSDHIWLPDIVLFNNA 123 Query: 380 ATTAGDYAL----RARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNS 547 G+Y + +A + G V W + + + +P D Q C FGS +N Sbjct: 124 ---DGNYEVTLMTKAVLKYTGEVLWSPPAIYKSYCEINVLYFPFDEQNCYMMFGSWTYNG 180 Query: 548 DEMD 559 +++D Sbjct: 181 NQVD 184 >UniRef50_P48169 Cluster: Gamma-aminobutyric acid receptor subunit alpha-4 precursor (GABA(A) receptor subunit alpha-4); n=26; Euteleostomi|Rep: Gamma-aminobutyric acid receptor subunit alpha-4 precursor (GABA(A) receptor subunit alpha-4) - Homo sapiens (Human) Length = 554 Score = 48.4 bits (110), Expect = 2e-04 Identities = 32/119 (26%), Positives = 52/119 (43%), Gaps = 3/119 (2%) Frame = +2 Query: 227 ESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYAL 406 E E T+ + + WIDKRL ++ + ++W PD N + + + Sbjct: 90 EMEYTMDVF--FRQTWIDKRLKYDGPIEILRLNNMMVTKVWTPDTFFRNGKKSVSHNMTA 147 Query: 407 RA---RVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDK 574 R+ NG++ + RL IS M+L ++P D C KFGS + EM + K Sbjct: 148 PNKLFRIMRNGTILYTMRLTISAECPMRLVDFPMDGHACPLKFGSYAYPKSEMIYTWTK 206 >UniRef50_UPI0000F1E62D Cluster: PREDICTED: hypothetical protein; n=1; Danio rerio|Rep: PREDICTED: hypothetical protein - Danio rerio Length = 357 Score = 47.6 bits (108), Expect = 4e-04 Identities = 32/129 (24%), Positives = 56/129 (43%), Gaps = 8/129 (6%) Frame = +2 Query: 260 LQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVS 439 L + W + LSW+ E G + ++LW PD+V+ V +NG V Sbjct: 63 LDVFWNIEGLSWDPEECGTDRISLPRKQLWMPDIVINEFMDENKAPVTYYLYVQHNGMVM 122 Query: 440 WIKRLDISTPISMQLDNWPNDMQTCTFKFGS-RMHNSD-------EMDFVIDKRIYSMFE 595 + + + M + +P D+Q CTF F S ++ SD E++ + + M Sbjct: 123 DDRPTHVISSCIMDIYTFPFDIQNCTFTFNSYKLFASDIQMLFFEEVEVTLANSLAVMKT 182 Query: 596 SGAWDVTDL 622 G W++ +L Sbjct: 183 KGEWELVNL 191 >UniRef50_UPI0000E20C28 Cluster: PREDICTED: gamma-aminobutyric acid A receptor, alpha 6 isoform 1; n=1; Pan troglodytes|Rep: PREDICTED: gamma-aminobutyric acid A receptor, alpha 6 isoform 1 - Pan troglodytes Length = 478 Score = 47.6 bits (108), Expect = 4e-04 Identities = 38/164 (23%), Positives = 69/164 (42%), Gaps = 8/164 (4%) Frame = +2 Query: 116 SLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESESTVRILADLQMNWIDK 283 ++S ++D+LL YD P + V +++ + + E + + W D+ Sbjct: 31 NVSRILDNLLEGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTDE 90 Query: 284 RLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRA---RVSNNGSVSWIKRL 454 RL + S + ++W PD N + A + R+ NG++ + RL Sbjct: 91 RLKFGGPTEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTMRL 150 Query: 455 DISTPISMQLDNWPNDMQTCTFKFGS-RMHNSDEMDFVIDKRIY 583 I+ M+L N+P D C KFGS +H + D + +Y Sbjct: 151 TINADCPMRLVNFPMDGHACPLKFGSYNVHFEGKKDNSSNSLLY 194 >UniRef50_Q8TA51 Cluster: Putative uncharacterized protein; n=3; Caenorhabditis|Rep: Putative uncharacterized protein - Caenorhabditis elegans Length = 428 Score = 47.6 bits (108), Expect = 4e-04 Identities = 28/98 (28%), Positives = 46/98 (46%), Gaps = 4/98 (4%) Frame = +2 Query: 260 LQMNWIDKRLSWNAGEWGCSTW-LVSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 433 L+++W D+RL WN EW L S RLW PD+ + + D+ + +N + Sbjct: 107 LKLSWKDRRLRWNPEEWKTEVLRLKSMGRLWSPDINSDKLQTGSQSTDFVNYHDIQSNYN 166 Query: 434 VSWIKRLDISTPISMQLD--NWPNDMQTCTFKFGSRMH 541 + RL+ Q+D +PND + C F S ++ Sbjct: 167 GNVTARLEFRMKAQCQIDYTEYPNDRKHCCFNLQSNLY 204 >UniRef50_Q22085 Cluster: Putative uncharacterized protein lgc-17; n=12; Caenorhabditis|Rep: Putative uncharacterized protein lgc-17 - Caenorhabditis elegans Length = 401 Score = 47.6 bits (108), Expect = 4e-04 Identities = 35/157 (22%), Positives = 66/157 (42%), Gaps = 10/157 (6%) Frame = +2 Query: 194 LTLHLRHANIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLL 370 L +L+ ++E E V ++ +L W D RLSWN+ + T V E++W P + Sbjct: 79 LLYYLKLVEVQEPEEKVSVVLELVEQWYDPRLSWNSSLYSNIPTVFVRQEKVWSPTLSAF 138 Query: 371 NA-AATTAGDYALR-ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHN 544 D R + + G + + +S+ M + +P D QTC F + N Sbjct: 139 GVNEIIDFRDQDFRIVSIDDIGYIQDYLSVRVSSNCPMDVSRFPFDSQTCQICFCLPIFN 198 Query: 545 -------SDEMDFVIDKRIYSMFESGAWDVTDLSSAV 634 ++ + ++ ++I + W V L++ V Sbjct: 199 IRQVKILNEIYEGILQEKIIKTMGNSEWKVVSLTNRV 235 >UniRef50_O18276 Cluster: Gamma-aminobutyric acid receptor subunit beta precursor (GABA(A) receptor subunit beta); n=3; Rhabditida|Rep: Gamma-aminobutyric acid receptor subunit beta precursor (GABA(A) receptor subunit beta) - Caenorhabditis elegans Length = 550 Score = 47.6 bits (108), Expect = 4e-04 Identities = 43/158 (27%), Positives = 71/158 (44%), Gaps = 10/158 (6%) Frame = +2 Query: 113 TSLSLMIDSLLATYD-RESPPDSKIVVNLTLHLRHAN---IRESESTVRILADLQMNWID 280 ++ S ++ LL YD R P + LT+ + A+ I E + + L W D Sbjct: 52 SNASSLLSDLLLDYDIRLRPGFGGDALLLTMDIIIASFDSISEVDMDYTLTMYLHQYWTD 111 Query: 281 KRLSWNAGEWGCSTWLVS---SERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSW 442 +RL W+ E +S S+ +W PD L N + + R R++ +G V++ Sbjct: 112 ERLRWS-NEIPIDEMTLSGEFSQNIWVPDTFLANDKHSYLHEVTERNKMLRINVDGKVAY 170 Query: 443 IKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEM 556 RL + SM L N+P D Q CT + S + + E+ Sbjct: 171 GMRLTSTLSCSMNLRNFPLDSQNCTVEIESYGYTTSEV 208 >UniRef50_Q4RN70 Cluster: Chromosome undetermined SCAF15016, whole genome shotgun sequence; n=22; Eukaryota|Rep: Chromosome undetermined SCAF15016, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 269 Score = 47.2 bits (107), Expect = 5e-04 Identities = 40/163 (24%), Positives = 71/163 (43%), Gaps = 7/163 (4%) Frame = +2 Query: 95 AECENATSLSLMIDSLLATYDRESPP---DSKIVVNLTLHLRHAN-IRESESTVRILADL 262 AE + L I L+ Y++ P + + V ++L + + I E L Sbjct: 17 AEVKEGEILPPTIQRLMKGYNKYLRPFFDNGPVTVGMSLDIASIDTISEINMDYTATIFL 76 Query: 263 QMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGS 433 + W D+RL + G S E LW PD ++++ + D + R+ NG+ Sbjct: 77 RQRWTDERLVFE-GNKSLSLDGRLVELLWVPDTFIVDSKKSFLHDITVENRLIRIFPNGT 135 Query: 434 VSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDF 562 V + R+ + +M L +P D QTCT + S +N +++ F Sbjct: 136 VLYALRITTTVACNMDLTKYPMDKQTCTLQLESWGYNINDVMF 178 >UniRef50_O16426 Cluster: Ligand-gated ion channel protein 1; n=2; Caenorhabditis elegans|Rep: Ligand-gated ion channel protein 1 - Caenorhabditis elegans Length = 371 Score = 47.2 bits (107), Expect = 5e-04 Identities = 39/163 (23%), Positives = 67/163 (41%), Gaps = 8/163 (4%) Frame = +2 Query: 167 PPDSKIVVNLTLHLRHANIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSER 343 PP +++ + + + L+ ++ E E V L D W D+RL WN E+ G S V Sbjct: 51 PPITELKLTMAM-LKLVDVVEVEEKVTFLFDYLAEWTDQRLKWNPLEYGGISHIYVPQRM 109 Query: 344 LWRPDVVLLNAAAT---TAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTC 514 +W P+V + +A + D A ++ NG+ + S + + +P D C Sbjct: 110 IWLPEVTIADAHEVKFFESDDAPRTAWINYNGTTGFYTSTVSSVICQLDVYKFPLDRHEC 169 Query: 515 TFKFGSRMHNSDEMDFVID----KRIYSMFESGAWDVTDLSSA 631 + +DE D + S +G W VT + A Sbjct: 170 GVSVLFHTYFADEYVIKSDMEPLPKPLSQLGNGEWKVTYIGVA 212 >UniRef50_A7S8Q4 Cluster: Predicted protein; n=3; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 311 Score = 46.8 bits (106), Expect = 7e-04 Identities = 34/147 (23%), Positives = 67/147 (45%), Gaps = 12/147 (8%) Frame = +2 Query: 218 NIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVL---LNAAAT 385 ++ + + + ++ W + L+W+ +G L VS++ +W PD++L ++ Sbjct: 34 DVNAKQQAITVYGWVRQMWNNSLLTWDPALFGGLDILHVSAKDVWVPDILLFYNVDEQDQ 93 Query: 386 TAGD---YALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMH----- 541 TAG Y + +NG+ W + + +++ +P D QTC KFGS H Sbjct: 94 TAGGRTTYKTDVIMYSNGTNKWRSPALLKSICKIKVKFFPFDSQTCKLKFGSFSHDITTL 153 Query: 542 NSDEMDFVIDKRIYSMFESGAWDVTDL 622 + M+ R Y ++G W + D+ Sbjct: 154 DMSPMNLTFPTRYYQ--KNGEWSIYDI 178 >UniRef50_A4FTX5 Cluster: CHRNB4 protein; n=1; Homo sapiens|Rep: CHRNB4 protein - Homo sapiens (Human) Length = 198 Score = 46.8 bits (106), Expect = 7e-04 Identities = 33/123 (26%), Positives = 58/123 (47%), Gaps = 8/123 (6%) Frame = +2 Query: 56 LLPFLLTCAIASAAECENATSLSLMIDSLL--ATYDRESPP--DSKIVVNLTLHLRHA-- 217 L+ F L A+ C A + ++D LL Y+ P S ++++ L L A Sbjct: 7 LVLFFLV-ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQL 65 Query: 218 -NIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTA 391 ++ E E + L+ W D RL+WN+ + G + + ++R+W PD+VL N + T Sbjct: 66 ISVNEREQIMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNKSLRTG 125 Query: 392 GDY 400 + Sbjct: 126 STW 128 >UniRef50_Q9UN88 Cluster: Gamma-aminobutyric acid receptor subunit theta precursor (GABA(A) receptor subunit theta); n=18; Tetrapoda|Rep: Gamma-aminobutyric acid receptor subunit theta precursor (GABA(A) receptor subunit theta) - Homo sapiens (Human) Length = 632 Score = 46.8 bits (106), Expect = 7e-04 Identities = 35/145 (24%), Positives = 60/145 (41%), Gaps = 7/145 (4%) Frame = +2 Query: 101 CENATSLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESESTVRILADLQM 268 C N + ++D +L+ YD P+ + + V +++++ I E I Sbjct: 53 CANEAVVQKILDRVLSRYDVRLRPNFGGAPVPVRISIYVTSIEQISEMNMDYTITMFFHQ 112 Query: 269 NWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSN---NGSVS 439 W D RL++ + E+LW PD LN+ D + RV +G+V Sbjct: 113 TWKDSRLAYYETTLNLTLDYRMHEKLWVPDCYFLNSKDAFVHDVTVENRVFQLHPDGTVR 172 Query: 440 WIKRLDISTPISMQLDNWPNDMQTC 514 + RL + S+ L +P D Q C Sbjct: 173 YGIRLTTTAACSLDLHKFPMDKQAC 197 >UniRef50_O00591 Cluster: Gamma-aminobutyric acid receptor subunit pi precursor (GABA(A) receptor subunit pi); n=19; Euteleostomi|Rep: Gamma-aminobutyric acid receptor subunit pi precursor (GABA(A) receptor subunit pi) - Homo sapiens (Human) Length = 440 Score = 46.8 bits (106), Expect = 7e-04 Identities = 40/164 (24%), Positives = 78/164 (47%), Gaps = 9/164 (5%) Frame = +2 Query: 98 ECENATSLSLM-IDSLLATYDRESPPD---SKIVVNLTLHLRH-ANIRESESTVRILADL 262 E + LSL ++L A Y++ P+ + + LTL + ++I ES L Sbjct: 29 EVGRSDKLSLPGFENLTAGYNKFLRPNFGGEPVQIALTLDIASISSISESNMDYTATIYL 88 Query: 263 QMNWIDKRLSWNAGE-WGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNG 430 + W+D+RL + + + LV E LW PD ++ + + + + R+ +NG Sbjct: 89 RQRWMDQRLVFEGNKSFTLDARLV--EFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNG 146 Query: 431 SVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDF 562 +V + R+ + +M L +P D QTC + S ++ ++++F Sbjct: 147 TVLYALRITTTVACNMDLSKYPMDTQTCKLQLESWGYDGNDVEF 190 >UniRef50_O14764 Cluster: Gamma-aminobutyric acid receptor subunit delta precursor (GABA(A) receptor subunit delta); n=27; Euteleostomi|Rep: Gamma-aminobutyric acid receptor subunit delta precursor (GABA(A) receptor subunit delta) - Homo sapiens (Human) Length = 452 Score = 46.8 bits (106), Expect = 7e-04 Identities = 38/149 (25%), Positives = 64/149 (42%), Gaps = 7/149 (4%) Frame = +2 Query: 131 IDSLLATYDRESPPD-SKIVVNLTLHLRHANI---RESESTVRILADLQMNWIDKRLSWN 298 +D L+A Y R P VN+ L L A+I E+ + L +W D RLS+N Sbjct: 44 LDGLIAGYARNFRPGIGGPPVNVALALEVASIDHISEANMEYTMTVFLHQSWRDSRLSYN 103 Query: 299 AGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTP 469 ++LW PD ++NA + D + R+ +G + + R+ + Sbjct: 104 HTNETLGLDSRFVDKLWLPDTFIVNAKSAWFHDVTVENKLIRLQPDGVILYSIRITSTVA 163 Query: 470 ISMQLDNWPNDMQTCTFKFGSRMHNSDEM 556 M L +P D Q C S ++S+++ Sbjct: 164 CDMDLAKYPMDEQECMLDLESYGYSSEDI 192 >UniRef50_UPI0000F1DA85 Cluster: PREDICTED: similar to MGC52789 protein; n=1; Danio rerio|Rep: PREDICTED: similar to MGC52789 protein - Danio rerio Length = 433 Score = 46.4 bits (105), Expect = 0.001 Identities = 27/114 (23%), Positives = 50/114 (43%), Gaps = 2/114 (1%) Frame = +2 Query: 221 IRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGD 397 + E ++ L W + +W ++ G S V + +W PD+V+ + T Sbjct: 77 VNEKAQSISTQVLLAHGWGNDFTTWKPDDFCGMSACSVKKDMVWTPDIVIAESIKTEIAT 136 Query: 398 YALR-ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEM 556 R+ + G V L +++ M L +P D Q+CT S +H+SD++ Sbjct: 137 MENAFVRLESRGIVFASNTLAVTSACKMDLHLFPFDTQSCTLTIMSSVHSSDQL 190 >UniRef50_UPI0000E45D33 Cluster: PREDICTED: similar to nicotinic acetylcholine receptor subunit alpha 6; n=2; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to nicotinic acetylcholine receptor subunit alpha 6 - Strongylocentrotus purpuratus Length = 440 Score = 46.4 bits (105), Expect = 0.001 Identities = 32/139 (23%), Positives = 59/139 (42%), Gaps = 8/139 (5%) Frame = +2 Query: 227 ESESTVRILADLQMNWIDKRLSWNAGE-WGCSTWLVSSERLWRPDVVL---LNAAATTAG 394 E+ V + +++++ W D+ L W+ E G + + ++WRPDVVL L+ + Sbjct: 77 ETHQMVTVRSNMRLQWTDEYLQWDPDENGGIYNITLKTNQVWRPDVVLDEDLDRDFISIP 136 Query: 395 DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVI-- 568 + V G++ W+ ++ M + +P D Q C F + +M F Sbjct: 137 EADTFVIVQYTGAMDWLFPAITTSACKMNIQYFPFDTQQCVLTFYPWTLDESKMRFFAKN 196 Query: 569 --DKRIYSMFESGAWDVTD 619 D +G W +TD Sbjct: 197 DEDALQARYVRNGIWSMTD 215 >UniRef50_Q7NDN8 Cluster: Glr4197 protein; n=1; Gloeobacter violaceus|Rep: Glr4197 protein - Gloeobacter violaceus Length = 359 Score = 46.0 bits (104), Expect = 0.001 Identities = 30/124 (24%), Positives = 56/124 (45%), Gaps = 5/124 (4%) Frame = +2 Query: 155 DRESPP----DSKIVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 319 D SPP D + VN ++L ++ + T ++ A L ++W D+RL+++ G Sbjct: 45 DMVSPPPPIADEPLTVNTGIYLIECYSLDDKAETFKVNAFLSLSWKDRRLAFDPVRSGVR 104 Query: 320 TWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPN 499 E +W P++ +N D + VS +G+V +++R + +P Sbjct: 105 VKTYEPEAIWIPEIRFVNVENARDAD-VVDISVSPDGTVQYLERFSARVLSPLDFRRYPF 163 Query: 500 DMQT 511 D QT Sbjct: 164 DSQT 167 >UniRef50_Q61I41 Cluster: Putative uncharacterized protein CBG10413; n=1; Caenorhabditis briggsae|Rep: Putative uncharacterized protein CBG10413 - Caenorhabditis briggsae Length = 366 Score = 46.0 bits (104), Expect = 0.001 Identities = 32/133 (24%), Positives = 59/133 (44%), Gaps = 4/133 (3%) Frame = +2 Query: 167 PPDSKIVVNLTLHLRHANIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSER 343 PP +++ + + + L+ ++ E E L D W D RL+WN E+ G S V + Sbjct: 69 PPMTELNLIMAM-LKLVDVVEVEEKATFLFDYSAEWTDHRLTWNPLEYGGISHIYVPQKS 127 Query: 344 LWRPDVVLLNAAAT---TAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTC 514 +W P++ + +A + D A ++ NG+V + S M + +P D C Sbjct: 128 IWLPEITIADAHEVKFFESEDAPSIAWINFNGTVGFYTSTVASVICEMDVFQFPMDQHEC 187 Query: 515 TFKFGSRMHNSDE 553 + + +DE Sbjct: 188 GVSVVANTYFADE 200 >UniRef50_O75311 Cluster: Glycine receptor subunit alpha-3 precursor; n=128; Euteleostomi|Rep: Glycine receptor subunit alpha-3 precursor - Homo sapiens (Human) Length = 464 Score = 46.0 bits (104), Expect = 0.001 Identities = 45/181 (24%), Positives = 77/181 (42%), Gaps = 11/181 (6%) Frame = +2 Query: 53 ILLPFLLTCAIASAAECENATSLSLMIDSLLAT---YDRESPPDSK-IVVNLTLHL---R 211 +LL + T SA S S +D L+ YD P+ K VN+T ++ Sbjct: 21 LLLSLVATKETDSARSRSAPMSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINS 80 Query: 212 HANIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERLWRPDVVLLNAAATT 388 +I E+ R+ L+ W D RL+++ S + +W+PD+ N Sbjct: 81 FGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGAN 140 Query: 389 AGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 559 + R+ NG+V + RL ++ M L N+P D+QTC + S + +++ Sbjct: 141 FHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFPMDVQTCIMQLESFGYTMNDLI 200 Query: 560 F 562 F Sbjct: 201 F 201 >UniRef50_UPI00015B60A2 Cluster: PREDICTED: similar to nicotinic acetylcholine receptor alpha6 subunit; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to nicotinic acetylcholine receptor alpha6 subunit - Nasonia vitripennis Length = 724 Score = 45.6 bits (103), Expect = 0.002 Identities = 29/113 (25%), Positives = 58/113 (51%), Gaps = 7/113 (6%) Frame = +2 Query: 128 MIDSLLATYDR-ESPPDSK---IVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLS 292 +++ LL+ Y+ E P +++ + V + L+ ++ E + A L++ W D L Sbjct: 73 LLNKLLSNYNTLERPVENESEPLQVKFGITLQQIIDVDEKNQILTTNAWLKLEWTDYNLQ 132 Query: 293 WNAGEW-GCSTWLVSSERLWRPDVVLLNAAAT-TAGDYALRARVSNNGSVSWI 445 WN E+ G ++ +LW+PDV++ N+A G + V++NGS ++ Sbjct: 133 WNESEFGGVKDLRITPSKLWKPDVLMYNSAEEGFDGTFQTNVVVTHNGSCLYV 185 >UniRef50_UPI0000EB6CC4 Cluster: glycine receptor, beta b; n=1; Danio rerio|Rep: glycine receptor, beta b - Danio rerio Length = 451 Score = 45.6 bits (103), Expect = 0.002 Identities = 40/163 (24%), Positives = 72/163 (44%), Gaps = 11/163 (6%) Frame = +2 Query: 110 ATSLSLMIDSLLATYDRESPPDSKIV-----VNLTLHLRHANIRESESTVRILADLQMNW 274 A S S +++ LL TYD P+ K + VN+ ++ +I+E+ R+ L+ W Sbjct: 61 ANSTSNILNKLLITYDPRIRPNFKGIPVEDRVNIFIN-SFGSIQETTMDYRVNIFLRQRW 119 Query: 275 IDKRLSWNAGEWGCSTWLVSSER---LWRPDVVLLNAAATTAGDYA---LRARVSNNGSV 436 D RL ++ + V + LW+PD+ N + D + + NG V Sbjct: 120 NDPRLRLPQ-DFKSDSLTVDPKMFKCLWKPDLFFANEKSANFHDVTQENILLFIFRNGDV 178 Query: 437 SWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFV 565 RL ++ + L +P D Q C + S + +D++ F+ Sbjct: 179 LISMRLSVTLSCPLDLTLFPMDTQRCKMQLESFGYTTDDLQFM 221 >UniRef50_UPI00006A0062 Cluster: UPI00006A0062 related cluster; n=1; Xenopus tropicalis|Rep: UPI00006A0062 UniRef100 entry - Xenopus tropicalis Length = 457 Score = 45.6 bits (103), Expect = 0.002 Identities = 34/130 (26%), Positives = 60/130 (46%), Gaps = 2/130 (1%) Frame = +2 Query: 251 LADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALR-ARVSN 424 +A + +W + ++W++ + G +VS +WRPD+ + + ++ Sbjct: 77 VACITQSWKNDFVNWDSNTYCGIEKVVVSDTLVWRPDLYIYEMVDDDDKSPKINYLKIYY 136 Query: 425 NGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDKRIYSMFESGA 604 NG V+ K L I+ SMQ +P D Q C+ FGS ++N D +Y M S + Sbjct: 137 NGIVTNSKPLRIAGSCSMQNFKFPFDEQNCSLTFGSYVYN--------DFEVYMMAASNS 188 Query: 605 WDVTDLSSAV 634 VT+ S + Sbjct: 189 SQVTENSKDI 198 >UniRef50_Q93323 Cluster: Putative uncharacterized protein lgc-21; n=2; Caenorhabditis|Rep: Putative uncharacterized protein lgc-21 - Caenorhabditis elegans Length = 409 Score = 45.6 bits (103), Expect = 0.002 Identities = 38/148 (25%), Positives = 60/148 (40%), Gaps = 7/148 (4%) Frame = +2 Query: 104 ENATSLS-LMIDSLLATYDRESPPDSKIVVNLT-LHLRHANIRESESTVRILADLQMNWI 277 E+A L+ L I +A+ + +N L+H + E + I L+++W Sbjct: 33 ESAKKLAKLNIPHAIASIPPNYLSQQPVTINFAQFTLQHFELNEHLKDISIHGYLELSWH 92 Query: 278 DKRLSWNAGEWGCSTWLVSS-ERLWRPDVVLLNAAATTAGDYALRAR---VSNNGSVSWI 445 D RL WN W + +V S +W P + N A R +N G+VS Sbjct: 93 DDRLMWNQDTWKKNKLVVHSFHHIWVPLLGSQNPENHLKNGDAFEIRKVETTNQGNVSAK 152 Query: 446 KRLDISTPI-SMQLDNWPNDMQTCTFKF 526 + T +N+PND+ C F F Sbjct: 153 VAFSLRTFCDDTDFENYPNDVYKCCFSF 180 >UniRef50_Q4W520 Cluster: Putative uncharacterized protein; n=1; Caenorhabditis elegans|Rep: Putative uncharacterized protein - Caenorhabditis elegans Length = 397 Score = 45.6 bits (103), Expect = 0.002 Identities = 30/133 (22%), Positives = 59/133 (44%), Gaps = 12/133 (9%) Frame = +2 Query: 200 LHLRHAN-IRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP------ 355 LH+ H + I++ + +++ W+D+RL WN + G T+ + +WR Sbjct: 62 LHVDHIHDIQDEQGVLKMALTFTFTWMDERLMWNPSNYSGIRTFSTTRHEMWRKKFWTPT 121 Query: 356 ----DVVLLNAAATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFK 523 DV + + + +S++G V R+ ++ P ++PND + CTF Sbjct: 122 LMMTDVPNSRRPSDVFKPFDMDIYISSSGMVRTSARMMLTIPCRTGFGSYPNDYKNCTFT 181 Query: 524 FGSRMHNSDEMDF 562 S + +D+ F Sbjct: 182 LMSPYY-ADQFRF 193 >UniRef50_A7T7Z5 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 152 Score = 45.6 bits (103), Expect = 0.002 Identities = 35/136 (25%), Positives = 60/136 (44%), Gaps = 10/136 (7%) Frame = +2 Query: 152 YDRESPP----DSKIVVNLTLHL-RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGC 316 YD+E P ++ V L L + ++ VR+ NW D L+W+ ++G Sbjct: 17 YDKEVRPVMNNHEQLKVYFALKLVQIVDVDGKSEAVRVNVWTTQNWKDPFLTWDPSDYGG 76 Query: 317 STWL-VSSERLWRPDVVLLNAAATT-AGD---YALRARVSNNGSVSWIKRLDISTPISMQ 481 + V+ +W P ++L N AA AG Y + +++NG+V+W + Sbjct: 77 IEEINVTPTMVWLPIIILYNNAANGFAGGPEKYKTKVVINSNGTVNWFAATQFLFSCKIN 136 Query: 482 LDNWPNDMQTCTFKFG 529 + +P D Q C FG Sbjct: 137 IRWFPFDEQYCYMTFG 152 >UniRef50_A7RTF8 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 262 Score = 45.6 bits (103), Expect = 0.002 Identities = 19/73 (26%), Positives = 38/73 (52%) Frame = +2 Query: 338 ERLWRPDVVLLNAAATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCT 517 +++W+PD + N ++T + + G V + +R+ + M L N+P D Q+C+ Sbjct: 35 KQIWKPDTYINNEKSSTVPENQFLLTIDPEGRVVYSQRMTVVASCMMYLRNYPMDTQSCS 94 Query: 518 FKFGSRMHNSDEM 556 F S N+D++ Sbjct: 95 ISFESYGMNNDDL 107 >UniRef50_UPI0000E4906A Cluster: PREDICTED: similar to nicotinic acetylcholine receptor subunit type G; n=1; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to nicotinic acetylcholine receptor subunit type G - Strongylocentrotus purpuratus Length = 705 Score = 45.2 bits (102), Expect = 0.002 Identities = 24/104 (23%), Positives = 49/104 (47%), Gaps = 2/104 (1%) Frame = +2 Query: 227 ESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDY- 400 E++ + I+A ++M+W D+ ++WN ++ G + LW PD+ L + + Y Sbjct: 35 ETQQQLTIMAYMRMSWRDEFITWNPDDYDGIELLALRPSDLWLPDIALYQSCSKEFISYQ 94 Query: 401 ALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 532 NG+ W +++ + + +P D+Q C FG+ Sbjct: 95 ETYVLCLYNGTCDWHFPAILTSTCKVDVRYFPFDIQLCDLTFGA 138 >UniRef50_A7SDE9 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 299 Score = 45.2 bits (102), Expect = 0.002 Identities = 36/124 (29%), Positives = 57/124 (45%), Gaps = 7/124 (5%) Frame = +2 Query: 182 IVVNLTLHLRH-ANIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSSE--RLWR 352 +VV+L++++ NI E+ + + W D+RL A S L E R+WR Sbjct: 4 VVVDLSIYVSSFGNIEEANMEYKFFGYFRQFWKDERL---ANRVNHSVILKGDEISRMWR 60 Query: 353 PDVVLLNA--AATTAGDYALRARVS--NNGSVSWIKRLDISTPISMQLDNWPNDMQTCTF 520 PD NA ++ T D + + V+ NG V + + I+ + L +P D Q C Sbjct: 61 PDPFCYNARKSSLTDADADINSMVTIHPNGDVVYSRMTIITAECELNLHKFPMDEQKCHL 120 Query: 521 KFGS 532 K GS Sbjct: 121 KIGS 124 >UniRef50_A7SVS1 Cluster: Predicted protein; n=5; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 318 Score = 44.8 bits (101), Expect = 0.003 Identities = 39/165 (23%), Positives = 72/165 (43%), Gaps = 8/165 (4%) Frame = +2 Query: 116 SLSLMIDSLLATYDRESPPDSKI-VVNLTLHLRHANIRE-SESTVRILADLQMN--WIDK 283 ++S ++D + YD+ P I V++ L + + E SE+ + D+ + W + Sbjct: 1 NISKLLDDVFKRYDKRIRPYYGIKAVDIQLDMLILSFGELSETNMEFTVDMYLGQFWKEP 60 Query: 284 RLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVS----NNGSVSWIKR 451 RL++ + V+SE+LW PD +N+ T + +GSV R Sbjct: 61 RLAFGIKREIILSG-VASEKLWVPDTFFVNSIDTKVHALLFSNKKVWINLTDGSVMLSAR 119 Query: 452 LDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDKRIYS 586 L + L N+P D QTC F S + ++++ ++ S Sbjct: 120 LTTRNSCKVDLRNYPMDEQTCHLPFESFSYEQKDLNYTWRSKVGS 164 >UniRef50_UPI000058727F Cluster: PREDICTED: similar to Chain B, Refined Structure Of The Nicotinic Acetylcholine Receptor At 4a Resolution.; n=2; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to Chain B, Refined Structure Of The Nicotinic Acetylcholine Receptor At 4a Resolution. - Strongylocentrotus purpuratus Length = 449 Score = 44.4 bits (100), Expect = 0.004 Identities = 33/116 (28%), Positives = 57/116 (49%), Gaps = 5/116 (4%) Frame = +2 Query: 182 IVVNLTLHLRHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSSERL-WRPD 358 + V+LTL ++ E + + + + + W D+RL+W +G +G T L RL W P Sbjct: 61 VTVHLTLQ-SVKDVNEKKQGMVGTSTITVVWRDERLTWMSGHYGNITVLTLPCRLVWTPS 119 Query: 359 VVLLNAAATTA----GDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTC 514 + L N+ + + ++ + N+G V+ L ST +M L +P D QTC Sbjct: 120 IRLGNSNSEDSRILKNPEDIKVFIKNDGQVTLETNLLHSTACAMNLALFPFDTQTC 175 >UniRef50_Q4S0E0 Cluster: Chromosome 2 SCAF14781, whole genome shotgun sequence; n=5; Euteleostomi|Rep: Chromosome 2 SCAF14781, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 525 Score = 44.4 bits (100), Expect = 0.004 Identities = 34/126 (26%), Positives = 56/126 (44%), Gaps = 5/126 (3%) Frame = +2 Query: 170 PDSKIVVNLTLHLRHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSS--ER 343 P + N+ ++ +I E+ R+ L+ W D RL+++ S L S + Sbjct: 113 PPVNVTCNIFIN-SFGSIAETTMDYRVNIFLRQKWNDPRLAYSKYP-DPSLDLDPSMLDS 170 Query: 344 LWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTC 514 +W+PD+ N D R+ NG+V + RL + M L N+P D+QTC Sbjct: 171 IWKPDLFFANEKGANFHDVTTDNKLLRIFKNGNVLYSIRLTLILSCPMDLKNFPMDVQTC 230 Query: 515 TFKFGS 532 T + S Sbjct: 231 TMQLES 236 >UniRef50_A7SRB3 Cluster: Predicted protein; n=3; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 331 Score = 44.4 bits (100), Expect = 0.004 Identities = 25/101 (24%), Positives = 49/101 (48%), Gaps = 1/101 (0%) Frame = +2 Query: 260 LQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 436 L+ W + L WN +G + + + +W PD+VL N + + + +S++G+ Sbjct: 62 LKCLWNNHLLRWNESHYGGIKSINIDPKLVWLPDIVLYNNGSMD--QFKTKVILSSDGTN 119 Query: 437 SWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 559 +W + + S+ + +P D Q CT FGS ++ +D Sbjct: 120 TWYAPSILRSRCSIDITFFPFDDQRCTLHFGSWTYDGLRVD 160 >UniRef50_Q4SRT3 Cluster: Chromosome undetermined SCAF14492, whole genome shotgun sequence; n=3; Clupeocephala|Rep: Chromosome undetermined SCAF14492, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 457 Score = 44.0 bits (99), Expect = 0.005 Identities = 28/125 (22%), Positives = 58/125 (46%), Gaps = 8/125 (6%) Frame = +2 Query: 218 NIRESESTVRILADLQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVL--LNAAATT 388 N+ E + + +W D+ L WN ++ + + +W PD+++ L + T Sbjct: 39 NVDEKNQVLTTYVWYRQSWTDEFLVWNPEDFDEVKQVSMPTANVWVPDILINELLSPVTC 98 Query: 389 AGDYALR-----ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDE 553 + D VS++G V K + + T ++ + N+P D+Q C+ F S +H D+ Sbjct: 99 SVDVGKSPDIPYVYVSHDGLVRNYKPIQVVTACTLNIYNFPFDVQKCSLTFQSWLHTIDD 158 Query: 554 MDFVI 568 ++ + Sbjct: 159 INITL 163 >UniRef50_Q4SRT2 Cluster: Chromosome undetermined SCAF14492, whole genome shotgun sequence; n=6; Euteleostomi|Rep: Chromosome undetermined SCAF14492, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 445 Score = 44.0 bits (99), Expect = 0.005 Identities = 25/100 (25%), Positives = 46/100 (46%), Gaps = 1/100 (1%) Frame = +2 Query: 272 WIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVSWIK 448 W D+ L W+ E+ G S + SE +W PDV++ V+ +G V + Sbjct: 74 WTDEFLVWDPEEFDGLSEISLPSEAVWIPDVIVTEFVDAGKAPPIPYVYVNASGWVRSYR 133 Query: 449 RLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVI 568 + + S+++ +P D C+ F S +H+ E+D + Sbjct: 134 PMQVVLACSLEMFAFPFDKHNCSLSFRSWLHSVKEIDLAL 173 >UniRef50_Q4SC79 Cluster: Chromosome undetermined SCAF14659, whole genome shotgun sequence; n=2; Euteleostomi|Rep: Chromosome undetermined SCAF14659, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 481 Score = 44.0 bits (99), Expect = 0.005 Identities = 34/135 (25%), Positives = 57/135 (42%), Gaps = 7/135 (5%) Frame = +2 Query: 131 IDSLLATYDRESPPD-SKIVVNLTLHLRHANI---RESESTVRILADLQMNWIDKRLSWN 298 +D L+ Y R P VN+ + + A+I E+ + L+ +W D RLS+N Sbjct: 32 LDDLMKGYARNFRPGIGGPPVNVAMAIEVASIDHISEANMEYTMTVFLRQSWHDDRLSYN 91 Query: 299 AGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTP 469 ++LW PD ++NA + D + R+ NG + + R+ + Sbjct: 92 HTNKTLGLDSRFVDKLWLPDTFIVNAKSAWFHDVTVENKLIRLQPNGVILYSSRITSTVA 151 Query: 470 ISMQLDNWPNDMQTC 514 M L +P D Q C Sbjct: 152 CDMDLTKYPMDEQEC 166 >UniRef50_Q9XTE5 Cluster: Putative uncharacterized protein lgc-31; n=3; Caenorhabditis|Rep: Putative uncharacterized protein lgc-31 - Caenorhabditis elegans Length = 503 Score = 44.0 bits (99), Expect = 0.005 Identities = 31/130 (23%), Positives = 58/130 (44%), Gaps = 7/130 (5%) Frame = +2 Query: 272 WIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVL---LNAAATTAGDYALRARVSNNGSVS 439 W D+ L WN + G +SS +W P+ L LN RV+ G V Sbjct: 12 WEDEFLKWNPSSYEGAEEIFLSSSDIWIPEFSLYYSLNFNDAVKLQSNNDVRVNYTGQVR 71 Query: 440 WIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDKRIYSM---FESGAWD 610 + + + + +P D+Q C+ FGS H++D + + + + S+ +++ W+ Sbjct: 72 YYIPFSSESLCKLDVKFFPFDVQQCSLLFGSWAHSNDSIKYSLYSQNLSLIDFYDNQEWE 131 Query: 611 VTDLSSAVXS 640 + +S+V S Sbjct: 132 LDTHNSSVHS 141 >UniRef50_Q8MM20 Cluster: Putative uncharacterized protein; n=3; Caenorhabditis|Rep: Putative uncharacterized protein - Caenorhabditis elegans Length = 428 Score = 44.0 bits (99), Expect = 0.005 Identities = 46/163 (28%), Positives = 72/163 (44%), Gaps = 11/163 (6%) Frame = +2 Query: 101 CENATSL--SLMIDSLLATYDRESPPDSKIVVNLTLHLRHANIRESESTVRILADLQMN- 271 C N T + L+ID L Y++ P ++ V + + ++ SE T DL MN Sbjct: 54 CANDTEIIDHLLIDRALY-YNKHKLPSPQVDVRIEMWVQEVT-SVSELTQDFEIDLYMNE 111 Query: 272 -WIDKRLSW---NAGEWGCS-TWLVSSERLWRPDVVLLNA--AATTAGDYA-LRARVSNN 427 W D L++ N + S W V + +W P+ +N+ A + + + V N Sbjct: 112 YWTDPGLAYDILNPCQGNLSFDWAVM-QNIWTPNTCFINSKKAQLHSSPFTNVFLMVFPN 170 Query: 428 GSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEM 556 GSV R+ + P M L +P D CT F S +N DE+ Sbjct: 171 GSVWSNWRIKSTGPCVMDLTKFPMDSIECTLTFESFNYNKDEV 213 >UniRef50_P25123 Cluster: Gamma-aminobutyric acid receptor subunit beta precursor (GABA(A) receptor subunit beta); n=45; Pancrustacea|Rep: Gamma-aminobutyric acid receptor subunit beta precursor (GABA(A) receptor subunit beta) - Drosophila melanogaster (Fruit fly) Length = 606 Score = 44.0 bits (99), Expect = 0.005 Identities = 40/152 (26%), Positives = 70/152 (46%), Gaps = 13/152 (8%) Frame = +2 Query: 116 SLSLMIDSLLATYDRESPPD---SKIVVNLTLH-LRHANIRESESTVRILADLQMNWIDK 283 ++S ++DS +YD+ P+ + V +T++ L +++ E + + W D Sbjct: 58 NISAILDSFSVSYDKRVRPNYGGPPVEVGVTMYVLSISSVSEVLMDFTLDFYFRQFWTDP 117 Query: 284 RLSWNAGEWGCSTWLVSSE---RLWRPDVVLLNAA------ATTAGDYALRARVSNNGSV 436 RL++ G T V SE +W PD +N ATT+ ++ RV ++GS+ Sbjct: 118 RLAYRKRP-GVETLSVGSEFIKNIWVPDTFFVNEKQSYFHIATTSNEFI---RVHHSGSI 173 Query: 437 SWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 532 + RL I+ M L +P D Q C + S Sbjct: 174 TRSIRLTITASCPMNLQYFPMDRQLCHIEIES 205 >UniRef50_Q4RU50 Cluster: Chromosome 1 SCAF14995, whole genome shotgun sequence; n=3; Tetraodontidae|Rep: Chromosome 1 SCAF14995, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 1044 Score = 43.6 bits (98), Expect = 0.007 Identities = 24/90 (26%), Positives = 40/90 (44%) Frame = +2 Query: 272 WIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVSWIKR 451 W + LSW+A E G + E+LW PD+ + + N G V Sbjct: 11 WDIEGLSWDAEECGTQRVSLPREKLWIPDIHITEFMDEDKSPRTPYVYIYNTGHVFDDSP 70 Query: 452 LDISTPISMQLDNWPNDMQTCTFKFGSRMH 541 L + + + + ++P D+Q C+ FGS +H Sbjct: 71 LRVVSTCKLGIYSFPFDIQNCSLTFGSYIH 100 >UniRef50_A2BGE6 Cluster: Glycine receptor, alpha 4b; n=5; Danio rerio|Rep: Glycine receptor, alpha 4b - Danio rerio (Zebrafish) (Brachydanio rerio) Length = 536 Score = 43.6 bits (98), Expect = 0.007 Identities = 37/145 (25%), Positives = 62/145 (42%), Gaps = 8/145 (5%) Frame = +2 Query: 152 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 319 YD P+ K VN+T ++ +I E+ R+ L+ W D RL++ Sbjct: 101 YDARIRPNFKGPPVNVTCNIFINSFGSITETTMDYRLNVFLRQQWNDPRLAYKEYPDDSL 160 Query: 320 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLD 487 S + +W+PD+ N + R+ NG+V + RL + M L Sbjct: 161 DLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFQNGNVLYSIRLTLILSCPMDLK 220 Query: 488 NWPNDMQTCTFKFGSRMHNSDEMDF 562 N+P D QTCT + S + +++ F Sbjct: 221 NFPMDTQTCTMQLESFGYTMNDLIF 245 >UniRef50_Q4BXY7 Cluster: Neurotransmitter-gated ion-channel ligand-binding; n=2; Chroococcales|Rep: Neurotransmitter-gated ion-channel ligand-binding - Crocosphaera watsonii Length = 340 Score = 43.6 bits (98), Expect = 0.007 Identities = 41/160 (25%), Positives = 70/160 (43%), Gaps = 4/160 (2%) Frame = +2 Query: 161 ESPPDSKIVVNL-TLHLRHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSS 337 + P ++I+V + TL L A I E E TV I L + W D R S + Sbjct: 34 DDPEITQILVGIYTLDL--AKINEVEQTVYIDFYLGLQWYDSRFDSALSNTNLSPYQRKL 91 Query: 338 ERLWRPDVVLLNAAATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCT 517 E +W+P++ ++N + +++ G V++ +R S+ L +P D QT Sbjct: 92 EEVWQPNLHIIN-QRNLDKELDEIVHINSQGIVTYRQRYYGKLATSLDLRRFPFDEQTIK 150 Query: 518 FKFGSRMHNSDEMDFVIDKR---IYSMFESGAWDVTDLSS 628 + S ++ +E+ FV + I S W + LSS Sbjct: 151 IELISFSYSPEEIHFVEAEELNGISSEISLVNWSIIGLSS 190 >UniRef50_UPI00015B4D8A Cluster: PREDICTED: similar to glutamate-gated chloride channel; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to glutamate-gated chloride channel - Nasonia vitripennis Length = 510 Score = 43.2 bits (97), Expect = 0.009 Identities = 32/130 (24%), Positives = 58/130 (44%), Gaps = 6/130 (4%) Frame = +2 Query: 161 ESPPDSKIVVNLTLHLRH-ANIRESESTVRILADLQMNWIDKRLSWN--AGEWGCSTWLV 331 E+ D +V + L +R A I + + + + W+D+RL +N G+ T L Sbjct: 56 ENGTDGPAIVRVNLFVRSIATISDIKMEYSVQLTFREQWVDERLRFNDFGGKLKYLT-LT 114 Query: 332 SSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPND 502 + R+W PD+ N + + R+ +GSV + R+ ++ M L +P D Sbjct: 115 DASRVWMPDLFFANEKEGHFHNIIMPNVYIRIFPDGSVLYSIRISLTLSCPMNLKLYPLD 174 Query: 503 MQTCTFKFGS 532 Q C+ + S Sbjct: 175 RQICSLRMAS 184 >UniRef50_UPI0000E4929C Cluster: PREDICTED: similar to nicotinic acetylcholine receptor beta 1 subunit variant 1; n=1; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to nicotinic acetylcholine receptor beta 1 subunit variant 1 - Strongylocentrotus purpuratus Length = 472 Score = 43.2 bits (97), Expect = 0.009 Identities = 28/96 (29%), Positives = 47/96 (48%), Gaps = 5/96 (5%) Frame = +2 Query: 260 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGD-YALR---ARVSN 424 +++ W D RLSWN E+ +L + E +W P V++ N+A + D +A+ A + + Sbjct: 78 VELMWKDPRLSWNESEYDGIQYLNLDPETIWMPRVIMQNSAMESVEDPFAMHRSYAIIFS 137 Query: 425 NGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 532 +G + T + N+P D QTCT S Sbjct: 138 DGYIRVTVPARFVTFCLTNVVNFPFDNQTCTVTVSS 173 >UniRef50_Q7PTU5 Cluster: ENSANGP00000015420; n=2; Anopheles gambiae str. PEST|Rep: ENSANGP00000015420 - Anopheles gambiae str. PEST Length = 238 Score = 43.2 bits (97), Expect = 0.009 Identities = 33/133 (24%), Positives = 56/133 (42%), Gaps = 7/133 (5%) Frame = +2 Query: 188 VNLTLH--LRHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPD 358 +N+T + L +I E S + + M W D L+WNA +W T L ++++ +W P Sbjct: 60 INITTYAVLYSFDISEYRSVMSFQVNYYMRWQDSSLAWNASDWSNITTLNINNDEIWSPQ 119 Query: 359 VVLLNAAATTAGDYAL---RARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFG 529 +++ + + NG VS IS S WP + C F Sbjct: 120 FENIDSDYEEQPSVSCLNPDCLLRVNGYVSCSPVCRISAKCSSDYSRWPFNTLVCRMWFT 179 Query: 530 SR-MHNSDEMDFV 565 +R DE++F+ Sbjct: 180 NRDKELVDEVNFL 192 >UniRef50_Q6U4B7 Cluster: Nicotinic acetylcholine receptor alpha 3 subunit; n=2; Nilaparvata lugens|Rep: Nicotinic acetylcholine receptor alpha 3 subunit - Nilaparvata lugens (Brown planthopper) Length = 575 Score = 43.2 bits (97), Expect = 0.009 Identities = 36/152 (23%), Positives = 63/152 (41%), Gaps = 6/152 (3%) Frame = +2 Query: 128 MIDSLLATYDRESPP----DSKIVVNLTLHLRHANIRESESTVRIL-ADLQMNWIDKRLS 292 + D LL+ Y++ P +++V L L L ++ +++ L++ W D + Sbjct: 31 LYDDLLSNYNKLIRPVGNNSDRLLVKLGLKLSQLIDVNGKNQIKVTNVWLEVTWYDYKGH 90 Query: 293 WNAGEWGCSTWLVSSERL-WRPDVVLLNAAATTAGDYALRARVSNNGSVSWIKRLDISTP 469 WN +G L L W PD+VL N A + V W + Sbjct: 91 WNPASYGGVDDLYVPLLLHWGPDIVLYNNADGKY-EVVTYGTAGILHKVEWKPPAIYKSF 149 Query: 470 ISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFV 565 + ++ +P D Q C KFGS +N ++D + Sbjct: 150 CEIDVEYFPFDEQKCVMKFGSWTYNGAQVDLL 181 >UniRef50_A7SN20 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 114 Score = 43.2 bits (97), Expect = 0.009 Identities = 30/108 (27%), Positives = 48/108 (44%), Gaps = 8/108 (7%) Frame = +2 Query: 272 WIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVL---LNAAATTAG---DYALRARVSNNG 430 W + WNA E+ G +V S ++W PDV L +N AG Y + ++G Sbjct: 1 WHHPYMRWNASEFDGIKEVMVDSSQIWVPDVTLYNNINEQDHKAGGRSTYKTDVNIYSDG 60 Query: 431 SVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDF-VID 571 W + + + +P D QTC +F S +S +M+ V+D Sbjct: 61 RAVWRSPAIFKSTCDVYVMYFPFDKQTCYLRFSSWRMDSSKMELRVLD 108 >UniRef50_P34271 Cluster: Acetylcholine receptor-like protein cup-4 precursor; n=3; Caenorhabditis|Rep: Acetylcholine receptor-like protein cup-4 precursor - Caenorhabditis elegans Length = 433 Score = 43.2 bits (97), Expect = 0.009 Identities = 27/131 (20%), Positives = 57/131 (43%), Gaps = 9/131 (6%) Frame = +2 Query: 185 VVNLTLHLRHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDV 361 +V++ H+ H +I + E T+ + + M W D+ L W+ ++ + V ++W+P + Sbjct: 74 IVDVHWHIIHVSINQREQTMTVHGHIYMRWFDEFLVWDPKDFNNIQYARVKKWQVWQPKI 133 Query: 362 VLLNAAA--TTAGDYALRARV------SNNGSVSWIKRLDISTPISMQLDNWPNDMQTCT 517 + N+A+ +A D++ A V + V I + ++P D+ C Sbjct: 134 KVSNSASGLGSAFDFSTSAHVIIQMMGKDRAKVEMYPTFSIKVGCAFDFTDYPYDLNKCA 193 Query: 518 FKFGSRMHNSD 550 S +D Sbjct: 194 INLFSTSTMAD 204 >UniRef50_UPI000065DFE4 Cluster: 5-hydroxytryptamine 3 receptor precursor (5-HT-3) (Serotonin-gated ion channel receptor) (5-HT3R).; n=1; Takifugu rubripes|Rep: 5-hydroxytryptamine 3 receptor precursor (5-HT-3) (Serotonin-gated ion channel receptor) (5-HT3R). - Takifugu rubripes Length = 488 Score = 42.7 bits (96), Expect = 0.012 Identities = 26/125 (20%), Positives = 58/125 (46%), Gaps = 8/125 (6%) Frame = +2 Query: 218 NIRESESTVRILADLQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLLN--AAATT 388 N+ E + + +W D+ L WN ++ + + +W PD+++ ++ T Sbjct: 39 NVDEKNQVLTTYVWYRQSWTDEFLVWNPEDFDEVKQVSIPTANVWVPDILINEFLSSVTC 98 Query: 389 AGDYALR-----ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDE 553 + D V+++G V K + + T ++ + N+P D+Q C+ F S +H D+ Sbjct: 99 SVDVGKSPDIPYVYVTHDGLVRNYKPIQVVTACTLNIYNFPFDVQKCSLTFQSWLHTIDD 158 Query: 554 MDFVI 568 ++ + Sbjct: 159 INITL 163 >UniRef50_A4TVG5 Cluster: Glycine receptor, alpha 4 subunit; n=1; Magnetospirillum gryphiswaldense|Rep: Glycine receptor, alpha 4 subunit - Magnetospirillum gryphiswaldense Length = 356 Score = 42.7 bits (96), Expect = 0.012 Identities = 45/162 (27%), Positives = 70/162 (43%), Gaps = 16/162 (9%) Frame = +2 Query: 221 IRESESTVRILADLQMNWIDKRLSW--NAGEWGCSTWL--VSSERL---WRPDVVLLNAA 379 I E+E T D+++ W D RL++ A G + + +RL W P VV N Sbjct: 48 ITENEGTFTATVDMRLRWRDLRLAYPAEAKAAGYQEYRNDAAEKRLAEIWNPGVVFSNMV 107 Query: 380 ATTAGDYALRA-RVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMH--NSD 550 Y R R+S NG V ++R + S LD +P D Q SR+ Sbjct: 108 GEPT--YQKRGLRISPNGQVELMQRTTATFTASFPLDKFPFDRQKLNVDLVSRLEPIQRV 165 Query: 551 EMDFVIDKRIYS----MFESGAW--DVTDLSSAVXSQDRGEV 658 ++DF D+ +S + E W + +L+ A + RGE+ Sbjct: 166 QLDFRQDELEFSNTRYISEIDGWIPGLVELAQAPVAAWRGEI 207 >UniRef50_O97141 Cluster: Nicotinic acetylcholine beta subunit homolog; n=1; Haementeria ghilianii|Rep: Nicotinic acetylcholine beta subunit homolog - Haementeria ghilianii (Amazon leech) Length = 233 Score = 42.7 bits (96), Expect = 0.012 Identities = 40/161 (24%), Positives = 67/161 (41%), Gaps = 5/161 (3%) Frame = +2 Query: 65 FLLTCAIASAAE---CENATSLSLMIDSLLATYDRE-SPPDSKIVVNLTLHLRHANIRES 232 FL+ +A + E C + + + L Y++E P D+ + L H + Sbjct: 4 FLVAVLVALSVENIFCSHLQGQTKLWKKLFDHYNKELEPEDAGLKFGLAFVRAHYEKQSH 63 Query: 233 ESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALR 409 E V + + +W DKRLSW E+ G ++ VS + LW PD L + AL Sbjct: 64 EVHVHVWE--RYSWTDKRLSWEPSEFDGVTSLRVSHDHLWLPDFQLYHGFEERVETKAL- 120 Query: 410 ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 532 +++ G + ++ + T + N C FK GS Sbjct: 121 --LTHEGHLVYVPAVLYKT----HCEKGANHSLHCHFKVGS 155 >UniRef50_UPI0000E47589 Cluster: PREDICTED: similar to gamma-aminobutyric acid A receptor beta 2S chain precursor - chicken; n=1; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to gamma-aminobutyric acid A receptor beta 2S chain precursor - chicken - Strongylocentrotus purpuratus Length = 418 Score = 42.3 bits (95), Expect = 0.015 Identities = 25/104 (24%), Positives = 51/104 (49%), Gaps = 3/104 (2%) Frame = +2 Query: 263 QMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGS 433 + +W D+RLS++ S + +ER+W PD N + D + R ++G+ Sbjct: 11 RQHWKDERLSYDPCLGNVSLSGILAERIWVPDTYFPNDKRSFVHDVTVTNKLLRFHHDGT 70 Query: 434 VSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFV 565 +++ R+ M L ++P D Q C+ + S + + +++FV Sbjct: 71 ITYGMRITSVASCYMDLVHYPMDEQNCSLEIESYGYTTADVNFV 114 >UniRef50_A7S8M2 Cluster: Predicted protein; n=2; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 303 Score = 42.3 bits (95), Expect = 0.015 Identities = 39/153 (25%), Positives = 75/153 (49%), Gaps = 14/153 (9%) Frame = +2 Query: 116 SLSLMIDSLLATYD---RESPPDS---KIVVNLTLH-LRHANIRESESTVRILADLQMNW 274 SL ++D ++ YD R + PD+ I V+L + + ++ E ++ + ++ W Sbjct: 2 SLDELLDVMVNCYDNRVRPTYPDNGPVNIQVDLFIQSVSKFSVINMEYSMTLY--IRQRW 59 Query: 275 IDKRLSWNAGEWGCSTWLVSSE----RLWRPDVVLLNA--AATTAGD-YALRARVSNNGS 433 +D+RL++ G+ ++ + ++W PD ++N + T +G ++ R+S NGS Sbjct: 60 LDQRLAY--GDMFPEDFITLGQEMVSQIWTPDTYIVNKKQSMTNSGHGMSMFIRISRNGS 117 Query: 434 VSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 532 V + + M L N+P D Q C FK S Sbjct: 118 VIFSAENTLVLVCQMDLRNFPMDEQQCDFKIES 150 >UniRef50_A7SDF1 Cluster: Predicted protein; n=2; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 273 Score = 41.9 bits (94), Expect = 0.020 Identities = 36/153 (23%), Positives = 69/153 (45%), Gaps = 10/153 (6%) Frame = +2 Query: 128 MIDSLLATYDRESPP---DSKIVVNLTLHLRH-ANIRESESTVRILADLQMNWIDKRLSW 295 +I+ L A YD+ P D ++ L++ NI+E+ ++ + W + RL Sbjct: 4 IINKLFADYDKTLRPGDGDGPTLITADLYVSSFGNIQETNMEYKVFGFFRQYWREDRL-- 61 Query: 296 NAGEWGCSTWLVSSE--RLWRPDVVLLNAAATTAG--DYALRARV--SNNGSVSWIKRLD 457 AG+ + L E +W+PD NA + D ++ + V +GSV + + + Sbjct: 62 -AGKHNKTVILTGKEIDNMWKPDPFCNNARESNLRETDESISSMVFLEPDGSVLYSRLII 120 Query: 458 ISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEM 556 ++ +M L +P D Q C K S + ++ + Sbjct: 121 VTAECNMNLRFFPMDEQKCYLKLSSYSYTTENI 153 >UniRef50_A7RNN1 Cluster: Predicted protein; n=2; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 317 Score = 41.9 bits (94), Expect = 0.020 Identities = 29/125 (23%), Positives = 57/125 (45%), Gaps = 11/125 (8%) Frame = +2 Query: 272 WIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLLNAA---ATTAG---DYALRARVSNNG 430 W + L WN ++G T V+ +W PD+VL N + +G + + ++G Sbjct: 72 WENPFLVWNESDYGGVHTLHVTFNDVWVPDIVLYNNGDPDLSLSGFTEKFKTFIILHSSG 131 Query: 431 SVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDKRIYS----MFES 598 + +W+ + + + +P D QTC+ FGS +++ + + + YS E+ Sbjct: 132 TCTWMSPTTFKSSCKLDITKFPFDSQTCSMTFGSWTYDNRLLSMDLLDKQYSHTERYVEN 191 Query: 599 GAWDV 613 G W + Sbjct: 192 GDWSL 196 >UniRef50_Q6U4B5 Cluster: Nicotinic acetylcholine receptor beta 1 subunit; n=5; Neoptera|Rep: Nicotinic acetylcholine receptor beta 1 subunit - Nilaparvata lugens (Brown planthopper) Length = 530 Score = 41.5 bits (93), Expect = 0.027 Identities = 29/108 (26%), Positives = 48/108 (44%), Gaps = 9/108 (8%) Frame = +2 Query: 272 WIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYALRAR------VSNNG 430 W D W+ +G + L + ++W+PD+VL N A G Y ++ + + NG Sbjct: 91 WSDSLQLWDEAHYGGVSHLRLPPGKVWKPDIVLFNNAD---GHYFVKYKSHQQDMIRPNG 147 Query: 431 SVSWIKRLDISTPISMQLD--NWPNDMQTCTFKFGSRMHNSDEMDFVI 568 + W+ S +D +P D QTC KFGS ++D + Sbjct: 148 ELIWLPPAIFHDRSSCTIDVKYFPFDEQTCVMKFGSWTFPGKQVDLAL 195 >UniRef50_P54244 Cluster: Acetylcholine receptor subunit alpha-type deg-3 precursor; n=2; Caenorhabditis|Rep: Acetylcholine receptor subunit alpha-type deg-3 precursor - Caenorhabditis elegans Length = 564 Score = 41.5 bits (93), Expect = 0.027 Identities = 31/157 (19%), Positives = 65/157 (41%), Gaps = 12/157 (7%) Frame = +2 Query: 179 KIVVNLTLHLRHANIRESESTVRILADLQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRP 355 K+ ++++L+ + + E +++ + W D+ L WN E+G ++ ++ LW P Sbjct: 79 KVHISISLY-QIIEVDEPSQNIKLNVWMIQKWRDEYLDWNPNEYGMINSTIIPFHHLWIP 137 Query: 356 DVVLLNAAATTAGD---YALRARVSN------NGSVSWIKRLDISTPISMQLDNWPNDMQ 508 D L N+ + + Y SN +S++ + + + +P D Q Sbjct: 138 DTYLYNSVKMSRDETERYMNIQATSNYWKGEKGAELSFLYPAIYTITCRLNIRFFPYDRQ 197 Query: 509 TCTFKFGSRMHNSDEMDFVIDKRI--YSMFESGAWDV 613 CT S ++ +D+ D + S + W V Sbjct: 198 NCTLTISSWTNSKSALDYYADTEVSMQSFIPNEEWQV 234 >UniRef50_UPI0000584BCE Cluster: PREDICTED: hypothetical protein; n=1; Strongylocentrotus purpuratus|Rep: PREDICTED: hypothetical protein - Strongylocentrotus purpuratus Length = 577 Score = 41.1 bits (92), Expect = 0.035 Identities = 22/103 (21%), Positives = 53/103 (51%), Gaps = 3/103 (2%) Frame = +2 Query: 227 ESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVL---LNAAATTAGD 397 E+ + ++ +++ W+D+ L W+ E+ + ++ + +W P++ L ++ + D Sbjct: 62 ETNQVITLVVYVRLMWVDEYLQWDPAEYDRTIMIIPKD-IWLPELTLDENVDRDFISFPD 120 Query: 398 YALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKF 526 + A + +G+V+W I+T + + +P D+Q CT F Sbjct: 121 TYITA--TPDGTVNWFFPAVITTTCKVDVRFFPFDIQECTLTF 161 >UniRef50_Q9NA62 Cluster: Putative uncharacterized protein; n=1; Caenorhabditis elegans|Rep: Putative uncharacterized protein - Caenorhabditis elegans Length = 434 Score = 41.1 bits (92), Expect = 0.035 Identities = 36/150 (24%), Positives = 70/150 (46%), Gaps = 10/150 (6%) Frame = +2 Query: 140 LLATYDRESPPDS---KIVVNLTLHLRHANIRESESTVRILADLQMNWIDKRLSWNAGEW 310 L+ Y R + P+ K+ V +T+ ++I T I + W DKRL+++ + Sbjct: 63 LMTNYSRNALPEPAPVKVEVEITIQ-DISDISAITGTFTIDYWISAIWNDKRLAFSHLDP 121 Query: 311 GCSTWLVSSE---RLWRPDVVLLNAAATTAGDYA---LRARVSNNGSVSWIK-RLDISTP 469 + + +LW P+V ++N+ +T D + + NG++ W+ R+ P Sbjct: 122 CRKNLSLDHDMEPKLWSPNVCIVNSKSTKVHDSPKPNILLMIFPNGTI-WLNYRIRSEAP 180 Query: 470 ISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 559 M L N+P D C+ F S +N+ +++ Sbjct: 181 CQMNLRNFPLDSIRCSLVFESYSYNAADVE 210 >UniRef50_A7RTX5 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 386 Score = 40.7 bits (91), Expect = 0.047 Identities = 30/144 (20%), Positives = 49/144 (34%), Gaps = 9/144 (6%) Frame = +2 Query: 242 VRILADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLN-AAATTAGDYALRAR- 415 + + A + W L W+ + S E +W PD L N AG Sbjct: 76 ITVNAWILQTWTHPVLKWSPRRRNVTKTRFSIEEVWVPDTALFNNGEKAVAGRQKFFESS 135 Query: 416 ---VSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEM----DFVIDK 574 ++ +G W ++ + WP D CT F SR + + EM D + Sbjct: 136 DVIMTYDGKAKWRTYATLTNKCKLNAKFWPMDEHVCTLTFSSRRYTASEMKIQSDTTNEH 195 Query: 575 RIYSMFESGAWDVTDLSSAVXSQD 646 + WDV ++ + D Sbjct: 196 ATTDHLSNSEWDVIKITVKTGNVD 219 >UniRef50_Q2PMX5 Cluster: GABA receptor; n=1; Tetranychus urticae|Rep: GABA receptor - Tetranychus urticae (Two-spotted spider mite) Length = 585 Score = 40.3 bits (90), Expect = 0.062 Identities = 35/125 (28%), Positives = 54/125 (43%), Gaps = 8/125 (6%) Frame = +2 Query: 182 IVVNLTLHLRHANIRESESTVRILADLQMN--WIDKRLSWNAGEWGCSTWLVSSE---RL 346 + V +T+H+ + SE + AD W D RLS+ A G S LV +E ++ Sbjct: 70 VKVGVTMHILTIS-SVSEVQMDFTADFYFRQLWRDSRLSFKARH-GISQILVDAEVADKI 127 Query: 347 WRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCT 517 W PD N + + R+S++G V RL ++ M L +P D Q C Sbjct: 128 WVPDTFFANEKQAYFHEATTKNTFLRISHDGQVLRSIRLTVTASCPMNLQYFPMDRQKCN 187 Query: 518 FKFGS 532 + S Sbjct: 188 IEIES 192 >UniRef50_O17402 Cluster: Putative uncharacterized protein; n=2; Caenorhabditis|Rep: Putative uncharacterized protein - Caenorhabditis elegans Length = 563 Score = 39.9 bits (89), Expect = 0.082 Identities = 25/88 (28%), Positives = 40/88 (45%), Gaps = 3/88 (3%) Frame = +2 Query: 260 LQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYA---LRARVSNNG 430 L M W D+RL+ N T + ++R+W PD+ +N+ + L V +G Sbjct: 175 LAMGWFDRRLAHNCTHPILVTSKLIADRIWYPDLYFVNSKYAYLQEVTTPNLMVIVYPDG 234 Query: 431 SVSWIKRLDISTPISMQLDNWPNDMQTC 514 + RLD++ M L +P D Q C Sbjct: 235 LIFKTMRLDVTLSCMMDLKLFPLDYQEC 262 >UniRef50_A7SDF0 Cluster: Predicted protein; n=2; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 349 Score = 39.9 bits (89), Expect = 0.082 Identities = 30/98 (30%), Positives = 48/98 (48%), Gaps = 6/98 (6%) Frame = +2 Query: 272 WIDKRLSWNAGEWGCSTWLVSSE--RLWRPDVVLLNA--AATTAGDYALRARVS--NNGS 433 W D+RL A S L E ++WRPD NA ++ TA D + + ++ NG Sbjct: 6 WKDERL---ANRLNKSVVLKGDEITKMWRPDPFCYNARESSLTASDDDINSMMTIHPNGD 62 Query: 434 VSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNS 547 V + + I+ M+L ++P D Q C K GS +++ Sbjct: 63 VVYSRMTIITAECEMKLHDFPMDEQQCHLKLGSYSYST 100 >UniRef50_Q94900 Cluster: Glutamate-gated chloride channel precursor; n=21; Pancrustacea|Rep: Glutamate-gated chloride channel precursor - Drosophila melanogaster (Fruit fly) Length = 456 Score = 39.9 bits (89), Expect = 0.082 Identities = 40/186 (21%), Positives = 77/186 (41%), Gaps = 14/186 (7%) Frame = +2 Query: 50 IILLPFLLTCAIASAAECENATSLSLMIDSLLAT--YDRESPP------DSKIVVNLTLH 205 I+ L + ++A+ A+ ++D +L YD P D +V + L Sbjct: 10 ILYFASLCSASLANNAKINFREKEKKVLDQILGAGKYDARIRPSGINGTDGPAIVRINLF 69 Query: 206 LRHA-NIRESESTVRILADLQMNWIDKRLSWN--AGEWGCSTWLVSSERLWRPDVVLLNA 376 +R I + + + + W D+RL ++ G T L + R+W PD+ N Sbjct: 70 VRSIMTISDIKMEYSVQLTFREQWTDERLKFDDIQGRLKYLT-LTEANRVWMPDLFFSNE 128 Query: 377 AATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNS 547 + + R+ NGSV + R+ ++ M L +P D Q C+ + S + Sbjct: 129 KEGHFHNIIMPNVYIRIFPNGSVLYSIRISLTLACPMNLKLYPLDRQICSLRMASYGWTT 188 Query: 548 DEMDFV 565 +++ F+ Sbjct: 189 NDLVFL 194 >UniRef50_Q61KY4 Cluster: Putative uncharacterized protein CBG09157; n=2; Caenorhabditis|Rep: Putative uncharacterized protein CBG09157 - Caenorhabditis briggsae Length = 371 Score = 33.1 bits (72), Expect(2) = 0.088 Identities = 19/80 (23%), Positives = 39/80 (48%), Gaps = 6/80 (7%) Frame = +2 Query: 140 LLATYDRESPP--DSKIVVNLTLHLRHAN---IRESESTVRILADLQMNWIDKRLSWNAG 304 LL Y + + P +S ++N+T ++ N + E +++L +W D+ L+W+ Sbjct: 15 LLDDYYKNARPVRNSSSILNVTALIQIYNLVEVNEKNEQIKLLLWFPQSWRDEYLTWDPE 74 Query: 305 EW-GCSTWLVSSERLWRPDV 361 EW G ++ +W D+ Sbjct: 75 EWNGIEKIIIPKAMIWLVDL 94 Score = 25.8 bits (54), Expect(2) = 0.088 Identities = 11/37 (29%), Positives = 23/37 (62%) Frame = +2 Query: 452 LDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDF 562 +D++ P+S+ ++P D Q C +FGS + ++ + F Sbjct: 92 VDLTCPMSVS--SFPFDSQLCALQFGSWSYPNNVLSF 126 >UniRef50_Q9TVI7 Cluster: Putative uncharacterized protein; n=2; Caenorhabditis|Rep: Putative uncharacterized protein - Caenorhabditis elegans Length = 538 Score = 39.5 bits (88), Expect = 0.11 Identities = 45/151 (29%), Positives = 67/151 (44%), Gaps = 12/151 (7%) Frame = +2 Query: 128 MIDSLLATYDRESPPDSKIV-VNLTLHL-RHANIRE--SESTVRILADLQMNWIDKRLSW 295 ++ LL+ YDR P K V V++ L + R + I E S ST+ IL W D LS+ Sbjct: 91 ILTELLSKYDRNLVPKMKGVDVDVELLIQRVSEISEIQSSSTMHIL--FSQIWHDPGLSF 148 Query: 296 NAGEWG-CSTWLVSSERL----WRPDVVLLNAAATTAGDYA---LRARVSNNGSVSWIKR 451 E C T L S R+ W P+V ++N+ + + + NG+V R Sbjct: 149 EHEEGAHCLTNLSLSHRMVDNIWLPNVCIVNSKGSAIHKSPTPNIFLAIFPNGTVWMNYR 208 Query: 452 LDISTPISMQLDNWPNDMQTCTFKFGSRMHN 544 + + +P M +P D CT F S N Sbjct: 209 VVVESPCEMDFSFFPMDRVMCTTIFESYAFN 239 >UniRef50_O61884 Cluster: Acetylcholine receptor protein 23; n=2; Caenorhabditis|Rep: Acetylcholine receptor protein 23 - Caenorhabditis elegans Length = 545 Score = 39.5 bits (88), Expect = 0.11 Identities = 34/138 (24%), Positives = 58/138 (42%), Gaps = 9/138 (6%) Frame = +2 Query: 176 SKIVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERLW 349 S I V L+L L + E + + + A W+D+ L W+ E+ T +++ + +W Sbjct: 50 SPINVTLSLQLYQIIQVNEPQQYLLLNAWAVERWVDQMLGWDPSEFDNETEIMARHDDIW 109 Query: 350 RPDVVLLNA------AATTAGDYALRARVSNNGS-VSWIKRLDISTPISMQLDNWPNDMQ 508 PD L N+ A+ L N G+ V + + L +P D Q Sbjct: 110 LPDTTLYNSLEMDDSASKKLTHVKLTTLGKNQGAMVELLYPTIYKISCLLNLKYFPFDTQ 169 Query: 509 TCTFKFGSRMHNSDEMDF 562 TC FGS ++ +D+ Sbjct: 170 TCRMTFGSWSFDNSLIDY 187 >UniRef50_A7S2G5 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 423 Score = 39.5 bits (88), Expect = 0.11 Identities = 25/86 (29%), Positives = 40/86 (46%), Gaps = 6/86 (6%) Frame = +2 Query: 128 MIDSLLATYDRESPP----DSKIVVNLTLHLRH-ANIRESESTVRILADLQMNWIDKRLS 292 +++ LL YDR P + + V L L L ++ E + ++ W + L+ Sbjct: 15 LLEKLLTGYDRNERPVLNDNESVTVTLGLTLNQIVDVDEKNQLLTTSTWIRQIWYNPLLT 74 Query: 293 WNAGEWG-CSTWLVSSERLWRPDVVL 367 WN E+G T VS +W PD+VL Sbjct: 75 WNVTEYGGLKTINVSPTIIWLPDIVL 100 >UniRef50_Q60NW3 Cluster: Putative uncharacterized protein CBG22525; n=1; Caenorhabditis briggsae|Rep: Putative uncharacterized protein CBG22525 - Caenorhabditis briggsae Length = 393 Score = 39.1 bits (87), Expect = 0.14 Identities = 32/157 (20%), Positives = 72/157 (45%), Gaps = 11/157 (7%) Frame = +2 Query: 125 LMIDSLLATYDRESPPDSKIVVNLTLHLRHANIRESESTVRILADLQMNWIDKRLSWNAG 304 ++I++ + R S P + I + HLR ++ +S+ T+ + + W+D+R W+ Sbjct: 40 ILINATASMPGRGSNPITAITMLHVDHLR--DLDQSKGTMSMSLSFLVTWMDERFRWDPK 97 Query: 305 EWGCSTWLVSSER------LWRPDVVLLNAAATTAG-----DYALRARVSNNGSVSWIKR 451 ++ S V+ ++ W P++ + + ++ + + V ++G+V R Sbjct: 98 DYH-SVRSVNGDKPSWSSAFWVPNIQIADMPSSQKSPGLFMNPGVEITVESSGTVKAFVR 156 Query: 452 LDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDF 562 ++ P ++P D Q C+F S + +DE F Sbjct: 157 TSMTIPCYFNFGDFPRDYQNCSFTLLSPYY-ADEFQF 192 >UniRef50_Q0GQQ7 Cluster: PH-sensitive chloride channel variant 4; n=2; Apocrita|Rep: PH-sensitive chloride channel variant 4 - Apis mellifera (Honeybee) Length = 489 Score = 39.1 bits (87), Expect = 0.14 Identities = 43/184 (23%), Positives = 77/184 (41%), Gaps = 10/184 (5%) Frame = +2 Query: 44 TYIILLPFLLTCAIASAAE--CENATSLSLMIDSLLAT--YDRE--SPPDSKIVVNLT-L 202 T + +L LT AE E+ S ++D+LL + YD+ P + VN++ L Sbjct: 34 TILCILTLALTLVTLVRAEDIFEDGKSDKEILDNLLLSTRYDKRLLPPVQGTLTVNVSVL 93 Query: 203 HLRHANIRESESTVRILADLQMNWIDKRLSW-NAGEWGCSTWLVSSERLWRPDV--VLLN 373 L A+ ES + LQ W D RL + N ++ + + +W PD ++ Sbjct: 94 LLSLASPDESSLKYEVEFLLQQQWYDPRLRYSNRSQYEFLNAIHHYDDIWLPDTYFIMHG 153 Query: 374 AAATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDE 553 R+ NG+V+++ R + +L+ +P D C+F S + Sbjct: 154 DFKDPLIPVHFALRIYRNGTVNYLMRRHLILSCQGRLNIFPFDDPLCSFAIESISYEQTA 213 Query: 554 MDFV 565 + +V Sbjct: 214 ITYV 217 Database: uniref50 Posted date: Oct 5, 2007 11:19 AM Number of letters in database: 575,637,011 Number of sequences in database: 1,657,284 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.279 0.0580 0.190 Matrix: BLOSUM62 Gap Penalties: Existence: 9, Extension: 2 Number of Hits to DB: 835,429,216 Number of Sequences: 1657284 Number of extensions: 18361211 Number of successful extensions: 56410 Number of sequences better than 10.0: 298 Number of HSP's better than 10.0 without gapping: 52697 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 56088 length of database: 575,637,011 effective HSP length: 100 effective length of database: 409,908,611 effective search space used: 77062818868 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 37 (14.9 bits) X3: 62 (25.0 bits) S1: 41 (21.7 bits)
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