Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= 030905E5_E08_e445_10.seq
(1552 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_O43924 Cluster: Retinal rod rhodopsin-sensitive cGMP 3'... 256 2e-66
UniRef50_UPI00006CF342 Cluster: GMP-PDE, delta subunit family pr... 131 4e-29
UniRef50_A2FVK6 Cluster: GMP-PDE, delta subunit family protein; ... 122 3e-26
UniRef50_Q3SE82 Cluster: PDEdelta, putative; n=1; Paramecium tet... 95 6e-18
UniRef50_Q3SE90 Cluster: UNC119 homologue, putative; n=10; Oligo... 44 0.011
UniRef50_Q3SE85 Cluster: UNC119 homologue, putative; n=2; Parame... 44 0.011
UniRef50_A4I307 Cluster: Putative uncharacterized protein; n=6; ... 42 0.058
UniRef50_Q5SYM3 Cluster: Unc-119 homolog; n=2; Eutheria|Rep: Unc... 39 0.31
UniRef50_Q13432 Cluster: Protein unc-119 homolog; n=54; Eumetazo... 38 0.71
UniRef50_Q4T421 Cluster: Chromosome undetermined SCAF9846, whole... 37 1.6
UniRef50_Q9XYQ2 Cluster: Protein unc-119 homolog; n=22; Eukaryot... 36 3.8
UniRef50_UPI00006CBA24 Cluster: hypothetical protein TTHERM_0055... 35 5.0
UniRef50_UPI0000545996 Cluster: PREDICTED: similar to ENSANGP000... 35 6.6
UniRef50_Q24F30 Cluster: Putative uncharacterized protein; n=1; ... 35 6.6
UniRef50_Q29VI2 Cluster: Tyrosine phosphatase; n=2; Filobasidiel... 35 6.6
>UniRef50_O43924 Cluster: Retinal rod rhodopsin-sensitive cGMP
3',5'-cyclic phosphodiesterase subunit delta; n=31;
Eumetazoa|Rep: Retinal rod rhodopsin-sensitive cGMP
3',5'-cyclic phosphodiesterase subunit delta - Homo
sapiens (Human)
Length = 150
Score = 256 bits (626), Expect = 2e-66
Identities = 113/148 (76%), Positives = 134/148 (90%)
Frame = +3
Query: 213 AKQDRVETILKGFQINWLNLRDADSGKILWQYNEDMSNPEVEHEARVPKRILKCRVVSRE 392
AK +R IL+GF++NW+NLRDA++GKILWQ ED+S P VEHEARVPK+ILKC+ VSRE
Sbjct: 3 AKDERAREILRGFKLNWMNLRDAETGKILWQGTEDLSVPGVEHEARVPKKILKCKAVSRE 62
Query: 393 LNFSSIESMDRFRLEQKVLFKGRCLEEWFFEFGYVIPNSTNTWQSVIESAPESQMMPANV 572
LNFSS E M++FRLEQKV FKG+CLEEWFFEFG+VIPNSTNTWQS+IE+APESQMMPA+V
Sbjct: 63 LNFSSTEQMEKFRLEQKVYFKGQCLEEWFFEFGFVIPNSTNTWQSLIEAAPESQMMPASV 122
Query: 573 LNGNVVIETKFFDGDLLITTSRVRLFYI 656
L GNV+IETKFFD DLL++TSRVRLFY+
Sbjct: 123 LTGNVIIETKFFDDDLLVSTSRVRLFYV 150
>UniRef50_UPI00006CF342 Cluster: GMP-PDE, delta subunit family
protein; n=1; Tetrahymena thermophila SB210|Rep:
GMP-PDE, delta subunit family protein - Tetrahymena
thermophila SB210
Length = 333
Score = 131 bits (317), Expect = 4e-29
Identities = 62/134 (46%), Positives = 95/134 (70%), Gaps = 2/134 (1%)
Frame = +3
Query: 231 ETILKGFQINWLNLRDADSGKILW--QYNEDMSNPEVEHEARVPKRILKCRVVSRELNFS 404
+ I +GFQIN L + DAD+G LW Q ++ + N E E +A +PK IL+C+ VSR++NFS
Sbjct: 156 QLIKQGFQINELTMGDADTGNKLWVCQDSQQLINSEKEIQANIPKEILQCKSVSRDINFS 215
Query: 405 SIESMDRFRLEQKVLFKGRCLEEWFFEFGYVIPNSTNTWQSVIESAPESQMMPANVLNGN 584
S ++ + L+Q G+ +E++ F+FG+VIP STN WQS+I+++ E M+P +L+GN
Sbjct: 216 SAHTIKKLSLKQIFSLNGQPIEQFSFDFGFVIPGSTNNWQSIIQASEE--MIPVEILSGN 273
Query: 585 VVIETKFFDGDLLI 626
+V+ETKF+D D LI
Sbjct: 274 LVVETKFYDEDNLI 287
>UniRef50_A2FVK6 Cluster: GMP-PDE, delta subunit family protein;
n=1; Trichomonas vaginalis G3|Rep: GMP-PDE, delta
subunit family protein - Trichomonas vaginalis G3
Length = 156
Score = 122 bits (294), Expect = 3e-26
Identities = 56/145 (38%), Positives = 98/145 (67%), Gaps = 2/145 (1%)
Frame = +3
Query: 225 RVETILKGFQINWLNLRDADSGKILWQYNEDMSNP--EVEHEARVPKRILKCRVVSRELN 398
+ + ILKGF++ L L+++ +GK+ W ++D ++ +A +PK +L V RE+
Sbjct: 12 QAQRILKGFKLISLTLKNSSNGKVAWT-SKDWTDDVFSAVKDAHLPKEMLGYPAVGREIV 70
Query: 399 FSSIESMDRFRLEQKVLFKGRCLEEWFFEFGYVIPNSTNTWQSVIESAPESQMMPANVLN 578
FS+ E++ FR++Q +L G+ +E+W ++FG+VIP S N+W++++E+A E M+PA L+
Sbjct: 71 FSTEEAIKEFRIQQDILVHGQNIEQWNYKFGFVIPGSENSWETIVEAAGEGNMLPAEYLS 130
Query: 579 GNVVIETKFFDGDLLITTSRVRLFY 653
GN+ I T F+ G+L I+ S VR+FY
Sbjct: 131 GNMYILTSFYAGNLFISRSVVRVFY 155
>UniRef50_Q3SE82 Cluster: PDEdelta, putative; n=1; Paramecium
tetraurelia|Rep: PDEdelta, putative - Paramecium
tetraurelia
Length = 154
Score = 94.7 bits (225), Expect = 6e-18
Identities = 44/148 (29%), Positives = 81/148 (54%)
Frame = +3
Query: 210 EAKQDRVETILKGFQINWLNLRDADSGKILWQYNEDMSNPEVEHEARVPKRILKCRVVSR 389
E Q V+ I GFQI + ++D+++ ++ W + ++ PK I+ + +R
Sbjct: 7 ELTQGEVQKIKDGFQIQKVIMKDSETQQVYWDSTSENITQDIMDITLDPK-IITSKAATR 65
Query: 390 ELNFSSIESMDRFRLEQKVLFKGRCLEEWFFEFGYVIPNSTNTWQSVIESAPESQMMPAN 569
+ FS+ E + L Q + +E + F+FG+V+P + NTW S I + P QM+P
Sbjct: 66 SIQFSTKEKLQDLILIQDAYLHDQKIEHFVFKFGFVMPETVNTWDSTIVNRPPEQMLPKE 125
Query: 570 VLNGNVVIETKFFDGDLLITTSRVRLFY 653
+ +GN++++ + F+ D LI +VR+FY
Sbjct: 126 IQSGNLIVDIQMFEQDHLIFNVKVRIFY 153
>UniRef50_Q3SE90 Cluster: UNC119 homologue, putative; n=10;
Oligohymenophorea|Rep: UNC119 homologue, putative -
Paramecium tetraurelia
Length = 187
Score = 44.0 bits (99), Expect = 0.011
Identities = 36/146 (24%), Positives = 70/146 (47%), Gaps = 18/146 (12%)
Frame = +3
Query: 270 LRDADSGKILWQYNEDMSNPEVEH-------EARVPK-----RILKCRVVSRELNFS-SI 410
+RD +SG++L++ D +E+ ++R K + + + + +L FS
Sbjct: 40 IRDMESGQVLFEVERDPDEESIENLPPALQDDSRRIKYHFGPQFFELKTIGAQLTFSVGD 99
Query: 411 ESMDRFRLEQKVLFKGRCLEEWFFEFGYVIPNSTNTWQSVIESAPE-----SQMMPANVL 575
+ + F + ++ F+ L + F+F + IPNSTNTW+ I + PE Q+M N
Sbjct: 100 KPIKNFTIIERHYFRNVLLRSYEFQFPFCIPNSTNTWEH-IYTIPEIAEDIKQLMIENPF 158
Query: 576 NGNVVIETKFFDGDLLITTSRVRLFY 653
+ ++ +F GD L+ ++ Y
Sbjct: 159 --DTKSDSFYFVGDTLVMHNKAEYDY 182
>UniRef50_Q3SE85 Cluster: UNC119 homologue, putative; n=2;
Paramecium tetraurelia|Rep: UNC119 homologue, putative -
Paramecium tetraurelia
Length = 174
Score = 44.0 bits (99), Expect = 0.011
Identities = 25/91 (27%), Positives = 45/91 (49%), Gaps = 2/91 (2%)
Frame = +3
Query: 270 LRDADSGKILWQYNEDMSNPEVEHEA-RVPKRILKCRVVSRELNFSSIES-MDRFRLEQK 443
LRDAD IL+ + D N + E + + + + + F + + + L +
Sbjct: 35 LRDADDNFILFDFENDEENQQQEVLSYQFTPQYFDIKTLGATKIFKTFDKPLKNLLLVDR 94
Query: 444 VLFKGRCLEEWFFEFGYVIPNSTNTWQSVIE 536
FK ++E+ F F + IP+STNTW+S+ +
Sbjct: 95 FYFKNNLIKEYEFCFPFCIPHSTNTWESMYD 125
>UniRef50_A4I307 Cluster: Putative uncharacterized protein; n=6;
Trypanosomatidae|Rep: Putative uncharacterized protein -
Leishmania infantum
Length = 197
Score = 41.5 bits (93), Expect = 0.058
Identities = 14/42 (33%), Positives = 30/42 (71%)
Frame = +3
Query: 411 ESMDRFRLEQKVLFKGRCLEEWFFEFGYVIPNSTNTWQSVIE 536
+ + +FR+ ++ F+ ++ + FEFG+ IP+STNTW+++ +
Sbjct: 110 QPVPKFRMIERHYFRNVLIKSFDFEFGFCIPHSTNTWEAIYD 151
>UniRef50_Q5SYM3 Cluster: Unc-119 homolog; n=2; Eutheria|Rep:
Unc-119 homolog - Mus musculus (Mouse)
Length = 262
Score = 39.1 bits (87), Expect = 0.31
Identities = 20/73 (27%), Positives = 40/73 (54%), Gaps = 1/73 (1%)
Frame = +3
Query: 366 LKCRVVSRELNFS-SIESMDRFRLEQKVLFKGRCLEEWFFEFGYVIPNSTNTWQSVIESA 542
L+ R V + F+ + ++ FR+ ++ F+ + L+ + F FG+ IP+S NT + + +
Sbjct: 138 LRLRQVGATVEFTVGDKPVNNFRMIERHYFRNQLLKSFDFHFGFCIPSSKNTCEHIYDFP 197
Query: 543 PESQMMPANVLNG 581
P S+ + L G
Sbjct: 198 PLSEELILKSLQG 210
>UniRef50_Q13432 Cluster: Protein unc-119 homolog; n=54;
Eumetazoa|Rep: Protein unc-119 homolog - Homo sapiens
(Human)
Length = 240
Score = 37.9 bits (84), Expect = 0.71
Identities = 18/71 (25%), Positives = 41/71 (57%), Gaps = 1/71 (1%)
Frame = +3
Query: 366 LKCRVVSRELNFS-SIESMDRFRLEQKVLFKGRCLEEWFFEFGYVIPNSTNTWQSVIESA 542
L+ R V + F+ + ++ FR+ ++ F+ + L+ + F FG+ IP+S NT + + +
Sbjct: 138 LRLRQVGATVEFTVGDKPVNNFRMIERHYFRNQLLKSFDFHFGFCIPSSKNTCEHIYDFP 197
Query: 543 PESQMMPANVL 575
P S+ + + ++
Sbjct: 198 PLSEELISEMI 208
>UniRef50_Q4T421 Cluster: Chromosome undetermined SCAF9846, whole
genome shotgun sequence; n=1; Tetraodon
nigroviridis|Rep: Chromosome undetermined SCAF9846,
whole genome shotgun sequence - Tetraodon nigroviridis
(Green puffer)
Length = 210
Score = 36.7 bits (81), Expect = 1.6
Identities = 14/40 (35%), Positives = 26/40 (65%)
Frame = +3
Query: 417 MDRFRLEQKVLFKGRCLEEWFFEFGYVIPNSTNTWQSVIE 536
++ FR+ ++ F+ L+ + F+FG+ IPNS NT + + E
Sbjct: 126 LNHFRMIERHYFRDHLLKSFDFDFGFCIPNSRNTCEHIYE 165
>UniRef50_Q9XYQ2 Cluster: Protein unc-119 homolog; n=22;
Eukaryota|Rep: Protein unc-119 homolog - Drosophila
melanogaster (Fruit fly)
Length = 265
Score = 35.5 bits (78), Expect = 3.8
Identities = 17/58 (29%), Positives = 32/58 (55%), Gaps = 1/58 (1%)
Frame = +3
Query: 366 LKCRVVSRELNFS-SIESMDRFRLEQKVLFKGRCLEEWFFEFGYVIPNSTNTWQSVIE 536
L + V + F+ + ++ FR+ ++ F+ R L+ + FEFG+ P S NT + + E
Sbjct: 161 LNLKTVGATVEFTVGSQPLNNFRMIERHFFRDRLLKTFDFEFGFCFPFSKNTVEHIYE 218
>UniRef50_UPI00006CBA24 Cluster: hypothetical protein
TTHERM_00558430; n=1; Tetrahymena thermophila SB210|Rep:
hypothetical protein TTHERM_00558430 - Tetrahymena
thermophila SB210
Length = 1322
Score = 35.1 bits (77), Expect = 5.0
Identities = 24/99 (24%), Positives = 47/99 (47%)
Frame = +3
Query: 225 RVETILKGFQINWLNLRDADSGKILWQYNEDMSNPEVEHEARVPKRILKCRVVSRELNFS 404
RV+ +LK Q N N+ + K +++ +D E++ + K+++KC+V +N+S
Sbjct: 662 RVDRMLKASQEN-PNIFNYLFFKFVYENKDDKELDELDKTQMIFKKLIKCQVEKAAINYS 720
Query: 405 SIESMDRFRLEQKVLFKGRCLEEWFFEFGYVIPNSTNTW 521
L K L ++ +F+F N+ NT+
Sbjct: 721 KSRDEYIKILSNKYLKNNFLIDLKYFDFSNSSNNNLNTY 759
>UniRef50_UPI0000545996 Cluster: PREDICTED: similar to
ENSANGP00000004777 isoform 2; n=3; Danio rerio|Rep:
PREDICTED: similar to ENSANGP00000004777 isoform 2 -
Danio rerio
Length = 261
Score = 34.7 bits (76), Expect = 6.6
Identities = 18/56 (32%), Positives = 33/56 (58%), Gaps = 1/56 (1%)
Frame = +3
Query: 366 LKCRVVSRELNFS-SIESMDRFRLEQKVLFKGRCLEEWFFEFGYVIPNSTNTWQSV 530
L R + L F+ +++++FRL +K F+ L+ + FE G+ IP+S NT + +
Sbjct: 152 LNLREIGAMLEFTVGGKAVNKFRLIEKHYFRDLLLKTFDFEIGFCIPHSRNTCEHI 207
>UniRef50_Q24F30 Cluster: Putative uncharacterized protein; n=1;
Tetrahymena thermophila SB210|Rep: Putative
uncharacterized protein - Tetrahymena thermophila SB210
Length = 1308
Score = 34.7 bits (76), Expect = 6.6
Identities = 22/59 (37%), Positives = 29/59 (49%), Gaps = 1/59 (1%)
Frame = -3
Query: 365 YTLRNPSFMLHFRIRHIFIVLPEDFS*VCITE-IQPVYLEAFKDGFHTVLFGFFGGQNF 192
Y+ NP F + RI I + P DF +C E QP Y +D +V GFF G +F
Sbjct: 497 YSCINPQFSIKSRINFIKPLTPSDFGSLCANEGSQPSYFIGQRDLQLSVNQGFFFGFSF 555
>UniRef50_Q29VI2 Cluster: Tyrosine phosphatase; n=2; Filobasidiella
neoformans|Rep: Tyrosine phosphatase - Cryptococcus
neoformans var. neoformans
Length = 763
Score = 34.7 bits (76), Expect = 6.6
Identities = 20/59 (33%), Positives = 31/59 (52%)
Frame = -1
Query: 457 PLNRTFCSNLNLSIDSMELKFNSRDTTLHFSIRFGTRASCSTSGFDISSLYCQRIFPES 281
PL+ + + +DS +++ NSR +L S G ASCS+S D+ S +C P S
Sbjct: 192 PLSSLSRDDSAMQVDSPQIRSNSRPGSLMASPALGGPASCSSSP-DLGSFFCDSPAPSS 249
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 1,067,272,968
Number of Sequences: 1657284
Number of extensions: 19054858
Number of successful extensions: 40846
Number of sequences better than 10.0: 15
Number of HSP's better than 10.0 without gapping: 37521
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 40356
length of database: 575,637,011
effective HSP length: 104
effective length of database: 403,279,475
effective search space used: 166151143700
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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