Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= 030905E5_E04_e413_10.seq
(1530 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
DQ317589-1|ABC59511.1| 147|Homo sapiens truncated surfactant pu... 89 5e-17
M60258-1|AAA36596.1| 526|Homo sapiens cerebroside sulfate activ... 88 9e-17
M60257-1|AAA36595.1| 524|Homo sapiens cerebroside sulfate activ... 88 9e-17
M60255-1|AAA36594.1| 527|Homo sapiens cerebroside sulfate activ... 88 9e-17
M32221-1|AAA60303.1| 524|Homo sapiens PSAP protein. 88 9e-17
J03077-1|AAA52560.1| 524|Homo sapiens GLBA protein. 88 9e-17
J03015-1|AAB59494.1| 524|Homo sapiens sphingolipid activator pr... 88 9e-17
D00422-1|BAA00321.1| 527|Homo sapiens sphingolipid activator pr... 88 9e-17
CR456746-1|CAG33027.1| 524|Homo sapiens PSAP protein. 88 9e-17
BT006849-1|AAP35495.1| 524|Homo sapiens prosaposin (variant Gau... 88 9e-17
BC007612-1|AAH07612.1| 524|Homo sapiens prosaposin (variant Gau... 88 9e-17
BC004275-1|AAH04275.1| 524|Homo sapiens prosaposin (variant Gau... 88 9e-17
BC001503-1|AAH01503.1| 524|Homo sapiens prosaposin (variant Gau... 88 9e-17
AL731541-2|CAI40837.1| 524|Homo sapiens prosaposin (variant Gau... 88 9e-17
AL731541-1|CAI40836.1| 559|Homo sapiens prosaposin (variant Gau... 88 9e-17
AK223290-1|BAD97010.1| 524|Homo sapiens prosaposin (variant Gau... 88 9e-17
AB209776-1|BAD93013.1| 530|Homo sapiens prosaposin variant prot... 88 9e-17
M24461-1|AAB59541.1| 381|Homo sapiens pulmonary surfactant-asso... 86 3e-16
AF400074-1|AAK77913.1| 381|Homo sapiens surfactant, pulmonary-a... 86 3e-16
J02761-1|AAA60212.1| 381|Homo sapiens pulmonary surfactant-asso... 85 5e-16
BC032785-1|AAH32785.1| 381|Homo sapiens surfactant, pulmonary-a... 85 5e-16
X57108-1|CAA40392.1| 210|Homo sapiens cerebroside sulfate activ... 85 6e-16
BC091483-1|AAH91483.1| 240|Homo sapiens PSAP protein protein. 58 2e-15
DQ991252-1|ABJ55983.1| 521|Homo sapiens prosaposin-like protein... 56 3e-07
BC068579-1|AAH68579.1| 543|Homo sapiens PSAPL1 protein protein. 56 3e-07
AK097698-1|BAC05143.1| 241|Homo sapiens protein ( Homo sapiens ... 56 3e-07
X57107-1|CAA40391.1| 67|Homo sapiens cerebroside sulfate activ... 49 5e-05
M16764-1|AAA88099.1| 286|Homo sapiens pulmonary surfactant-asso... 42 0.006
>DQ317589-1|ABC59511.1| 147|Homo sapiens truncated surfactant
pulmonary-associated protein B protein.
Length = 147
Score = 88.6 bits (210), Expect = 5e-17
Identities = 35/133 (26%), Positives = 66/133 (49%)
Frame = +2
Query: 89 LAPTNTKXHLVGNIRCSWGPSYWCSNFSTGRECKATHHCVSRFWPKYIFPEDTDDICKIC 268
L T ++ C+ GP +WC + +C+A HC+ W DD+C+ C
Sbjct: 13 LCGPGTAAWTTSSLACAQGPEFWCQSLEQALQCRALGHCLQEVWGHV----GADDLCQEC 68
Query: 269 TDMVKQARDQLESNTTQEDLKEVFEGSCKLIPIKVVAKKCMQLADDFVPELVETLASQMN 448
D+V + Q+ ++E E C ++P+K++ +C Q+ DD+ P +++ +Q++
Sbjct: 69 EDIVHILNKMAKEAIFQDTMREFLEQECNVLPLKLLMPQCNQVLDDYFPLVIDYFQNQID 128
Query: 449 PNIVCSVAGLCNN 487
N +C GLC +
Sbjct: 129 SNSICMHLGLCKS 141
>M60258-1|AAA36596.1| 526|Homo sapiens cerebroside sulfate
activator protein protein.
Length = 526
Score = 87.8 bits (208), Expect = 9e-17
Identities = 43/140 (30%), Positives = 71/140 (50%), Gaps = 1/140 (0%)
Frame = +2
Query: 116 LVGNIRCSWGPSYWCSNFSTGRECKATHHCVSRFWPKYIFPEDTDDICKICTDMVKQARD 295
++G C+ G + WC N T +C A HC+ W K P C IC D+V A D
Sbjct: 19 VLGLKECTRGSAVWCQNVKTASDCGAVKHCLQTVWNK---PTVKSLPCDICKDVVTAAGD 75
Query: 296 QLESNTTQEDLKEVFEGSCKLIPIKVVAKKCMQLADDFVPELVETLASQMN-PNIVCSVA 472
L+ N T+E++ E +C +P ++ C ++ D ++P +++ + +M+ P VCS
Sbjct: 76 MLKDNATEEEILVYLEKTCDWLPKPNMSASCKEIVDSYLPVILDIIKGEMSRPGEVCSAL 135
Query: 473 GLCNNYKIDALLFEYNSQKE 532
LC + + L E N QK+
Sbjct: 136 NLCES--LQKHLAELNHQKQ 153
Score = 85.0 bits (201), Expect = 6e-16
Identities = 42/181 (23%), Positives = 92/181 (50%), Gaps = 2/181 (1%)
Frame = +2
Query: 224 KYIFPEDTDDICKICTDMVKQARDQLESNTTQEDLKEVFEGSCKLIPIKVVAKKCMQLAD 403
K+ P +D C++C +VK+ +++N T++++ + F+ C +P K ++++C ++ D
Sbjct: 306 KHEVPAKSDVYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLP-KSLSEECQEVVD 364
Query: 404 DFVPELVETLASQMNPNIVCSVAGLCNNYKIDALLFEYNSQKERVVGCNNCQGTVGALRK 583
+ ++ L +++P +VCS+ LC+ ++ AL K+ C C+ VG L +
Sbjct: 365 TYGSSILSILLEEVSPELVCSMLHLCSGTRLPALTVHVTQPKDGGF-CEVCKKLVGYLDR 423
Query: 584 KFDQ-TPYEDFLVGLLKVCRGM-DSLSDSCSMLVFKYYENIVDAVKKDLTPQSICHVSGQ 757
++ + ++ L L K C + D C V +Y +++ + + + P +C G
Sbjct: 424 NLEKNSTKQEILAALEKGCSFLPDPYQKQCDQFVAEYEPVLIEILVEVMDPSFVCLKIGA 483
Query: 758 C 760
C
Sbjct: 484 C 484
Score = 52.0 bits (119), Expect = 6e-06
Identities = 17/35 (48%), Positives = 20/35 (57%)
Frame = +2
Query: 116 LVGNIRCSWGPSYWCSNFSTGRECKATHHCVSRFW 220
L+G +C WGPSYWC N T +C A HC W
Sbjct: 491 LLGTEKCIWGPSYWCQNTETAAQCNAVEHCKRHVW 525
Score = 43.2 bits (97), Expect = 0.003
Identities = 46/203 (22%), Positives = 88/203 (43%), Gaps = 27/203 (13%)
Frame = +2
Query: 236 PEDTDDICKICTDMVKQARDQLESNTT--QEDLKEVFEGSCKLIP-IKVVAKKCMQLADD 406
P+D D+C+ C MV + + +N+T Q ++ V E +L P + ++K + +
Sbjct: 191 PKDNGDVCQDCIQMVTDIQTAVRTNSTFVQALVEHVKEECDRLGPGMADISKNYISQYSE 250
Query: 407 FVPELVETLASQMNPNIVCSVAGLCNNYK-----------------IDALLFEYNSQKER 535
+++ + Q P +C++ G C+ K I AL +K
Sbjct: 251 IAIQMMMHMDQQ--PKEICALVGFCDEVKEMPMQTLVPAKVASKNVIPALELVEPIKKHE 308
Query: 536 V-----VGCNNCQGTVGALRKKFDQTPYE-DFLVGLLKVCRGM-DSLSDSCSMLVFKYYE 694
V V C C+ V + K D E + L K+C + SLS+ C +V Y
Sbjct: 309 VPAKSDVYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLPKSLSEECQEVVDTYGS 368
Query: 695 NIVDAVKKDLTPQSICHVSGQCT 763
+I+ + ++++P+ +C + C+
Sbjct: 369 SILSILLEEVSPELVCSMLHLCS 391
>M60257-1|AAA36595.1| 524|Homo sapiens cerebroside sulfate
activator protein protein.
Length = 524
Score = 87.8 bits (208), Expect = 9e-17
Identities = 43/140 (30%), Positives = 71/140 (50%), Gaps = 1/140 (0%)
Frame = +2
Query: 116 LVGNIRCSWGPSYWCSNFSTGRECKATHHCVSRFWPKYIFPEDTDDICKICTDMVKQARD 295
++G C+ G + WC N T +C A HC+ W K P C IC D+V A D
Sbjct: 19 VLGLKECTRGSAVWCQNVKTASDCGAVKHCLQTVWNK---PTVKSLPCDICKDVVTAAGD 75
Query: 296 QLESNTTQEDLKEVFEGSCKLIPIKVVAKKCMQLADDFVPELVETLASQMN-PNIVCSVA 472
L+ N T+E++ E +C +P ++ C ++ D ++P +++ + +M+ P VCS
Sbjct: 76 MLKDNATEEEILVYLEKTCDWLPKPNMSASCKEIVDSYLPVILDIIKGEMSRPGEVCSAL 135
Query: 473 GLCNNYKIDALLFEYNSQKE 532
LC + + L E N QK+
Sbjct: 136 NLCES--LQKHLAELNHQKQ 153
Score = 85.0 bits (201), Expect = 6e-16
Identities = 42/181 (23%), Positives = 92/181 (50%), Gaps = 2/181 (1%)
Frame = +2
Query: 224 KYIFPEDTDDICKICTDMVKQARDQLESNTTQEDLKEVFEGSCKLIPIKVVAKKCMQLAD 403
K+ P +D C++C +VK+ +++N T++++ + F+ C +P K ++++C ++ D
Sbjct: 304 KHEVPAKSDVYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLP-KSLSEECQEVVD 362
Query: 404 DFVPELVETLASQMNPNIVCSVAGLCNNYKIDALLFEYNSQKERVVGCNNCQGTVGALRK 583
+ ++ L +++P +VCS+ LC+ ++ AL K+ C C+ VG L +
Sbjct: 363 TYGSSILSILLEEVSPELVCSMLHLCSGTRLPALTVHVTQPKDGGF-CEVCKKLVGYLDR 421
Query: 584 KFDQ-TPYEDFLVGLLKVCRGM-DSLSDSCSMLVFKYYENIVDAVKKDLTPQSICHVSGQ 757
++ + ++ L L K C + D C V +Y +++ + + + P +C G
Sbjct: 422 NLEKNSTKQEILAALEKGCSFLPDPYQKQCDQFVAEYEPVLIEILVEVMDPSFVCLKIGA 481
Query: 758 C 760
C
Sbjct: 482 C 482
Score = 52.0 bits (119), Expect = 6e-06
Identities = 17/35 (48%), Positives = 20/35 (57%)
Frame = +2
Query: 116 LVGNIRCSWGPSYWCSNFSTGRECKATHHCVSRFW 220
L+G +C WGPSYWC N T +C A HC W
Sbjct: 489 LLGTEKCIWGPSYWCQNTETAAQCNAVEHCKRHVW 523
Score = 42.7 bits (96), Expect = 0.003
Identities = 47/203 (23%), Positives = 86/203 (42%), Gaps = 27/203 (13%)
Frame = +2
Query: 236 PEDTDDICKICTDMVKQARDQLESNTT--QEDLKEVFEGSCKLIP-IKVVAKKCMQLADD 406
P+D D+C+ C MV + + +N+T Q ++ V E +L P + ++K +
Sbjct: 191 PKDNGDVCQDCIQMVTDIQTAVRTNSTFVQALVEHVKEECDRLGPGMADISKNYISQ--- 247
Query: 407 FVPELVETLASQMNPNIVCSVAGLCNNYK-----------------IDALLFEYNSQKER 535
E+ + M P +C++ G C+ K I AL +K
Sbjct: 248 -YSEIAIQMMMHMQPKEICALVGFCDEVKEMPMQTLVPAKVASKNVIPALELVEPIKKHE 306
Query: 536 V-----VGCNNCQGTVGALRKKFDQTPYE-DFLVGLLKVCRGM-DSLSDSCSMLVFKYYE 694
V V C C+ V + K D E + L K+C + SLS+ C +V Y
Sbjct: 307 VPAKSDVYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLPKSLSEECQEVVDTYGS 366
Query: 695 NIVDAVKKDLTPQSICHVSGQCT 763
+I+ + ++++P+ +C + C+
Sbjct: 367 SILSILLEEVSPELVCSMLHLCS 389
>M60255-1|AAA36594.1| 527|Homo sapiens cerebroside sulfate
activator protein protein.
Length = 527
Score = 87.8 bits (208), Expect = 9e-17
Identities = 43/140 (30%), Positives = 71/140 (50%), Gaps = 1/140 (0%)
Frame = +2
Query: 116 LVGNIRCSWGPSYWCSNFSTGRECKATHHCVSRFWPKYIFPEDTDDICKICTDMVKQARD 295
++G C+ G + WC N T +C A HC+ W K P C IC D+V A D
Sbjct: 19 VLGLKECTRGSAVWCQNVKTASDCGAVKHCLQTVWNK---PTVKSLPCDICKDVVTAAGD 75
Query: 296 QLESNTTQEDLKEVFEGSCKLIPIKVVAKKCMQLADDFVPELVETLASQMN-PNIVCSVA 472
L+ N T+E++ E +C +P ++ C ++ D ++P +++ + +M+ P VCS
Sbjct: 76 MLKDNATEEEILVYLEKTCDWLPKPNMSASCKEIVDSYLPVILDIIKGEMSRPGEVCSAL 135
Query: 473 GLCNNYKIDALLFEYNSQKE 532
LC + + L E N QK+
Sbjct: 136 NLCES--LQKHLAELNHQKQ 153
Score = 85.0 bits (201), Expect = 6e-16
Identities = 42/181 (23%), Positives = 92/181 (50%), Gaps = 2/181 (1%)
Frame = +2
Query: 224 KYIFPEDTDDICKICTDMVKQARDQLESNTTQEDLKEVFEGSCKLIPIKVVAKKCMQLAD 403
K+ P +D C++C +VK+ +++N T++++ + F+ C +P K ++++C ++ D
Sbjct: 307 KHEVPAKSDVYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLP-KSLSEECQEVVD 365
Query: 404 DFVPELVETLASQMNPNIVCSVAGLCNNYKIDALLFEYNSQKERVVGCNNCQGTVGALRK 583
+ ++ L +++P +VCS+ LC+ ++ AL K+ C C+ VG L +
Sbjct: 366 TYGSSILSILLEEVSPELVCSMLHLCSGTRLPALTVHVTQPKDGGF-CEVCKKLVGYLDR 424
Query: 584 KFDQ-TPYEDFLVGLLKVCRGM-DSLSDSCSMLVFKYYENIVDAVKKDLTPQSICHVSGQ 757
++ + ++ L L K C + D C V +Y +++ + + + P +C G
Sbjct: 425 NLEKNSTKQEILAALEKGCSFLPDPYQKQCDQFVAEYEPVLIEILVEVMDPSFVCLKIGA 484
Query: 758 C 760
C
Sbjct: 485 C 485
Score = 52.0 bits (119), Expect = 6e-06
Identities = 17/35 (48%), Positives = 20/35 (57%)
Frame = +2
Query: 116 LVGNIRCSWGPSYWCSNFSTGRECKATHHCVSRFW 220
L+G +C WGPSYWC N T +C A HC W
Sbjct: 492 LLGTEKCIWGPSYWCQNTETAAQCNAVEHCKRHVW 526
Score = 44.4 bits (100), Expect = 0.001
Identities = 46/203 (22%), Positives = 88/203 (43%), Gaps = 27/203 (13%)
Frame = +2
Query: 236 PEDTDDICKICTDMVKQARDQLESNTT--QEDLKEVFEGSCKLIP-IKVVAKKCMQLADD 406
P+D D+C+ C MV + + +N+T Q ++ V E +L P + ++K + +
Sbjct: 191 PKDNGDVCQDCIQMVTDIQTAVRTNSTFVQALVEHVKEECDRLGPGMADISKNYISQYSE 250
Query: 407 FVPELVETLASQMNPNIVCSVAGLCNNYK-----------------IDALLFEYNSQKER 535
+++ + Q P +C++ G C+ K I AL +K
Sbjct: 251 IAIQMMMHMQDQ-QPKEICALVGFCDEVKEMPMQTLVPAKVASKNVIPALELVEPIKKHE 309
Query: 536 V-----VGCNNCQGTVGALRKKFDQTPYE-DFLVGLLKVCRGM-DSLSDSCSMLVFKYYE 694
V V C C+ V + K D E + L K+C + SLS+ C +V Y
Sbjct: 310 VPAKSDVYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLPKSLSEECQEVVDTYGS 369
Query: 695 NIVDAVKKDLTPQSICHVSGQCT 763
+I+ + ++++P+ +C + C+
Sbjct: 370 SILSILLEEVSPELVCSMLHLCS 392
>M32221-1|AAA60303.1| 524|Homo sapiens PSAP protein.
Length = 524
Score = 87.8 bits (208), Expect = 9e-17
Identities = 43/140 (30%), Positives = 71/140 (50%), Gaps = 1/140 (0%)
Frame = +2
Query: 116 LVGNIRCSWGPSYWCSNFSTGRECKATHHCVSRFWPKYIFPEDTDDICKICTDMVKQARD 295
++G C+ G + WC N T +C A HC+ W K P C IC D+V A D
Sbjct: 19 VLGLKECTRGSAVWCQNVKTASDCGAVKHCLQTVWNK---PTVKSLPCDICKDVVTAAGD 75
Query: 296 QLESNTTQEDLKEVFEGSCKLIPIKVVAKKCMQLADDFVPELVETLASQMN-PNIVCSVA 472
L+ N T+E++ E +C +P ++ C ++ D ++P +++ + +M+ P VCS
Sbjct: 76 MLKDNATEEEILVYLEKTCDWLPKPNMSASCKEIVDSYLPVILDIIKGEMSRPGEVCSAL 135
Query: 473 GLCNNYKIDALLFEYNSQKE 532
LC + + L E N QK+
Sbjct: 136 NLCES--LQKHLAELNHQKQ 153
Score = 85.0 bits (201), Expect = 6e-16
Identities = 42/181 (23%), Positives = 92/181 (50%), Gaps = 2/181 (1%)
Frame = +2
Query: 224 KYIFPEDTDDICKICTDMVKQARDQLESNTTQEDLKEVFEGSCKLIPIKVVAKKCMQLAD 403
K+ P +D C++C +VK+ +++N T++++ + F+ C +P K ++++C ++ D
Sbjct: 304 KHEVPAKSDVYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLP-KSLSEECQEVVD 362
Query: 404 DFVPELVETLASQMNPNIVCSVAGLCNNYKIDALLFEYNSQKERVVGCNNCQGTVGALRK 583
+ ++ L +++P +VCS+ LC+ ++ AL K+ C C+ VG L +
Sbjct: 363 TYGSSILSILLEEVSPELVCSMLHLCSGTRLPALTVHVTQPKDGGF-CEVCKKLVGYLDR 421
Query: 584 KFDQ-TPYEDFLVGLLKVCRGM-DSLSDSCSMLVFKYYENIVDAVKKDLTPQSICHVSGQ 757
++ + ++ L L K C + D C V +Y +++ + + + P +C G
Sbjct: 422 NLEKNSTKQEILAALEKGCSFLPDPYQKQCDQFVAEYEPVLIEILVEVMDPSFVCLKIGA 481
Query: 758 C 760
C
Sbjct: 482 C 482
Score = 52.0 bits (119), Expect = 6e-06
Identities = 17/35 (48%), Positives = 20/35 (57%)
Frame = +2
Query: 116 LVGNIRCSWGPSYWCSNFSTGRECKATHHCVSRFW 220
L+G +C WGPSYWC N T +C A HC W
Sbjct: 489 LLGTEKCIWGPSYWCQNTETAAQCNAVEHCKRHVW 523
Score = 46.4 bits (105), Expect = 3e-04
Identities = 48/202 (23%), Positives = 85/202 (42%), Gaps = 26/202 (12%)
Frame = +2
Query: 236 PEDTDDICKICTDMVKQARDQLESNTT--QEDLKEVFEGSCKLIPIKVVAKKCMQLADDF 409
P+D D+C+ C MV + + +N+T Q ++ V E +L P +A C +
Sbjct: 191 PKDNGDVCQDCIQMVTDIQTAVRTNSTFVQALVEHVKEECDRLGP--GMADICKNYISQY 248
Query: 410 VPELVETLASQMNPNIVCSVAGLCNNYK-----------------IDALLFEYNSQKERV 538
E+ + M P +C++ G C+ K I AL +K V
Sbjct: 249 -SEIAIQMMMHMQPKEICALVGFCDEVKEMPMQTLVPAKVASKNVIPALELVEPIKKHEV 307
Query: 539 -----VGCNNCQGTVGALRKKFDQTPYE-DFLVGLLKVCRGM-DSLSDSCSMLVFKYYEN 697
V C C+ V + K D E + L K+C + SLS+ C +V Y +
Sbjct: 308 PAKSDVYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLPKSLSEECQEVVDTYGSS 367
Query: 698 IVDAVKKDLTPQSICHVSGQCT 763
I+ + ++++P+ +C + C+
Sbjct: 368 ILSILLEEVSPELVCSMLHLCS 389
>J03077-1|AAA52560.1| 524|Homo sapiens GLBA protein.
Length = 524
Score = 87.8 bits (208), Expect = 9e-17
Identities = 43/140 (30%), Positives = 71/140 (50%), Gaps = 1/140 (0%)
Frame = +2
Query: 116 LVGNIRCSWGPSYWCSNFSTGRECKATHHCVSRFWPKYIFPEDTDDICKICTDMVKQARD 295
++G C+ G + WC N T +C A HC+ W K P C IC D+V A D
Sbjct: 19 VLGLKECTRGSAVWCQNVKTASDCGAVKHCLQTVWNK---PTVKSLPCDICKDVVTAAGD 75
Query: 296 QLESNTTQEDLKEVFEGSCKLIPIKVVAKKCMQLADDFVPELVETLASQMN-PNIVCSVA 472
L+ N T+E++ E +C +P ++ C ++ D ++P +++ + +M+ P VCS
Sbjct: 76 MLKDNATEEEILVYLEKTCDWLPKPNMSASCKEIVDSYLPVILDIIKGEMSRPGEVCSAL 135
Query: 473 GLCNNYKIDALLFEYNSQKE 532
LC + + L E N QK+
Sbjct: 136 NLCES--LQKHLAELNHQKQ 153
Score = 85.0 bits (201), Expect = 6e-16
Identities = 42/181 (23%), Positives = 92/181 (50%), Gaps = 2/181 (1%)
Frame = +2
Query: 224 KYIFPEDTDDICKICTDMVKQARDQLESNTTQEDLKEVFEGSCKLIPIKVVAKKCMQLAD 403
K+ P +D C++C +VK+ +++N T++++ + F+ C +P K ++++C ++ D
Sbjct: 304 KHEVPAKSDVYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLP-KSLSEECQEVVD 362
Query: 404 DFVPELVETLASQMNPNIVCSVAGLCNNYKIDALLFEYNSQKERVVGCNNCQGTVGALRK 583
+ ++ L +++P +VCS+ LC+ ++ AL K+ C C+ VG L +
Sbjct: 363 TYGSSILSILLEEVSPELVCSMLHLCSGTRLPALTVHVTQPKDGGF-CEVCKKLVGYLDR 421
Query: 584 KFDQ-TPYEDFLVGLLKVCRGM-DSLSDSCSMLVFKYYENIVDAVKKDLTPQSICHVSGQ 757
++ + ++ L L K C + D C V +Y +++ + + + P +C G
Sbjct: 422 NLEKNSTKQEILAALEKGCSFLPDPYQKQCDQFVAEYEPVLIEILVEVMDPSFVCLKIGA 481
Query: 758 C 760
C
Sbjct: 482 C 482
Score = 52.0 bits (119), Expect = 6e-06
Identities = 17/35 (48%), Positives = 20/35 (57%)
Frame = +2
Query: 116 LVGNIRCSWGPSYWCSNFSTGRECKATHHCVSRFW 220
L+G +C WGPSYWC N T +C A HC W
Sbjct: 489 LLGTEKCIWGPSYWCQNTETAAQCNAVEHCKRHVW 523
Score = 46.4 bits (105), Expect = 3e-04
Identities = 48/202 (23%), Positives = 85/202 (42%), Gaps = 26/202 (12%)
Frame = +2
Query: 236 PEDTDDICKICTDMVKQARDQLESNTT--QEDLKEVFEGSCKLIPIKVVAKKCMQLADDF 409
P+D D+C+ C MV + + +N+T Q ++ V E +L P +A C +
Sbjct: 191 PKDNGDVCQDCIQMVTDIQTAVRTNSTFVQALVEHVKEECDRLGP--GMADICKNYISQY 248
Query: 410 VPELVETLASQMNPNIVCSVAGLCNNYK-----------------IDALLFEYNSQKERV 538
E+ + M P +C++ G C+ K I AL +K V
Sbjct: 249 -SEIAIQMMMHMQPKEICALVGFCDEVKEMPMQTLVPAKVASKNVIPALELVEPIKKHEV 307
Query: 539 -----VGCNNCQGTVGALRKKFDQTPYE-DFLVGLLKVCRGM-DSLSDSCSMLVFKYYEN 697
V C C+ V + K D E + L K+C + SLS+ C +V Y +
Sbjct: 308 PAKSDVYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLPKSLSEECQEVVDTYGSS 367
Query: 698 IVDAVKKDLTPQSICHVSGQCT 763
I+ + ++++P+ +C + C+
Sbjct: 368 ILSILLEEVSPELVCSMLHLCS 389
>J03015-1|AAB59494.1| 524|Homo sapiens sphingolipid activator
precursor protein.
Length = 524
Score = 87.8 bits (208), Expect = 9e-17
Identities = 43/140 (30%), Positives = 71/140 (50%), Gaps = 1/140 (0%)
Frame = +2
Query: 116 LVGNIRCSWGPSYWCSNFSTGRECKATHHCVSRFWPKYIFPEDTDDICKICTDMVKQARD 295
++G C+ G + WC N T +C A HC+ W K P C IC D+V A D
Sbjct: 19 VLGLKECTRGSAVWCQNVKTASDCGAVKHCLQTVWNK---PTVKSLPCDICKDVVTAAGD 75
Query: 296 QLESNTTQEDLKEVFEGSCKLIPIKVVAKKCMQLADDFVPELVETLASQMN-PNIVCSVA 472
L+ N T+E++ E +C +P ++ C ++ D ++P +++ + +M+ P VCS
Sbjct: 76 MLKDNATEEEILVYLEKTCDWLPKPNMSASCKEIVDSYLPVILDIIKGEMSRPGEVCSAL 135
Query: 473 GLCNNYKIDALLFEYNSQKE 532
LC + + L E N QK+
Sbjct: 136 NLCES--LQKHLAELNHQKQ 153
Score = 85.0 bits (201), Expect = 6e-16
Identities = 42/181 (23%), Positives = 92/181 (50%), Gaps = 2/181 (1%)
Frame = +2
Query: 224 KYIFPEDTDDICKICTDMVKQARDQLESNTTQEDLKEVFEGSCKLIPIKVVAKKCMQLAD 403
K+ P +D C++C +VK+ +++N T++++ + F+ C +P K ++++C ++ D
Sbjct: 304 KHEVPAKSDVYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLP-KSLSEECQEVVD 362
Query: 404 DFVPELVETLASQMNPNIVCSVAGLCNNYKIDALLFEYNSQKERVVGCNNCQGTVGALRK 583
+ ++ L +++P +VCS+ LC+ ++ AL K+ C C+ VG L +
Sbjct: 363 TYGSSILSILLEEVSPELVCSMLHLCSGTRLPALTVHVTQPKDGGF-CEVCKKLVGYLDR 421
Query: 584 KFDQ-TPYEDFLVGLLKVCRGM-DSLSDSCSMLVFKYYENIVDAVKKDLTPQSICHVSGQ 757
++ + ++ L L K C + D C V +Y +++ + + + P +C G
Sbjct: 422 NLEKNSTKQEILAALEKGCSFLPDPYQKQCDQFVAEYEPVLIEILVEVMDPSFVCLKIGA 481
Query: 758 C 760
C
Sbjct: 482 C 482
Score = 52.0 bits (119), Expect = 6e-06
Identities = 17/35 (48%), Positives = 20/35 (57%)
Frame = +2
Query: 116 LVGNIRCSWGPSYWCSNFSTGRECKATHHCVSRFW 220
L+G +C WGPSYWC N T +C A HC W
Sbjct: 489 LLGTEKCIWGPSYWCQNTETAAQCNAVEHCKRHVW 523
Score = 46.4 bits (105), Expect = 3e-04
Identities = 48/202 (23%), Positives = 85/202 (42%), Gaps = 26/202 (12%)
Frame = +2
Query: 236 PEDTDDICKICTDMVKQARDQLESNTT--QEDLKEVFEGSCKLIPIKVVAKKCMQLADDF 409
P+D D+C+ C MV + + +N+T Q ++ V E +L P +A C +
Sbjct: 191 PKDNGDVCQDCIQMVTDIQTAVRTNSTFVQALVEHVKEECDRLGP--GMADICKNYISQY 248
Query: 410 VPELVETLASQMNPNIVCSVAGLCNNYK-----------------IDALLFEYNSQKERV 538
E+ + M P +C++ G C+ K I AL +K V
Sbjct: 249 -SEIAIQMMMHMQPKEICALVGFCDEVKEMPMQTLVPAKVASKNVIPALELVEPIKKHEV 307
Query: 539 -----VGCNNCQGTVGALRKKFDQTPYE-DFLVGLLKVCRGM-DSLSDSCSMLVFKYYEN 697
V C C+ V + K D E + L K+C + SLS+ C +V Y +
Sbjct: 308 PAKSDVYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLPKSLSEECQEVVDTYGSS 367
Query: 698 IVDAVKKDLTPQSICHVSGQCT 763
I+ + ++++P+ +C + C+
Sbjct: 368 ILSILLEEVSPELVCSMLHLCS 389
>D00422-1|BAA00321.1| 527|Homo sapiens sphingolipid activator
proteins protein.
Length = 527
Score = 87.8 bits (208), Expect = 9e-17
Identities = 43/140 (30%), Positives = 71/140 (50%), Gaps = 1/140 (0%)
Frame = +2
Query: 116 LVGNIRCSWGPSYWCSNFSTGRECKATHHCVSRFWPKYIFPEDTDDICKICTDMVKQARD 295
++G C+ G + WC N T +C A HC+ W K P C IC D+V A D
Sbjct: 19 VLGLKECTRGSAVWCQNVKTASDCGAVKHCLQTVWNK---PTVKSLPCDICKDVVTAAGD 75
Query: 296 QLESNTTQEDLKEVFEGSCKLIPIKVVAKKCMQLADDFVPELVETLASQMN-PNIVCSVA 472
L+ N T+E++ E +C +P ++ C ++ D ++P +++ + +M+ P VCS
Sbjct: 76 MLKDNATEEEILVYLEKTCDWLPKPNMSASCKEIVDSYLPVILDIIKGEMSRPGEVCSAL 135
Query: 473 GLCNNYKIDALLFEYNSQKE 532
LC + + L E N QK+
Sbjct: 136 NLCES--LQKHLAELNHQKQ 153
Score = 85.0 bits (201), Expect = 6e-16
Identities = 42/181 (23%), Positives = 92/181 (50%), Gaps = 2/181 (1%)
Frame = +2
Query: 224 KYIFPEDTDDICKICTDMVKQARDQLESNTTQEDLKEVFEGSCKLIPIKVVAKKCMQLAD 403
K+ P +D C++C +VK+ +++N T++++ + F+ C +P K ++++C ++ D
Sbjct: 307 KHEVPAKSDVYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLP-KSLSEECQEVVD 365
Query: 404 DFVPELVETLASQMNPNIVCSVAGLCNNYKIDALLFEYNSQKERVVGCNNCQGTVGALRK 583
+ ++ L +++P +VCS+ LC+ ++ AL K+ C C+ VG L +
Sbjct: 366 TYGSSILSILLEEVSPELVCSMLHLCSGTRLPALTVHVTQPKDGGF-CEVCKKLVGYLDR 424
Query: 584 KFDQ-TPYEDFLVGLLKVCRGM-DSLSDSCSMLVFKYYENIVDAVKKDLTPQSICHVSGQ 757
++ + ++ L L K C + D C V +Y +++ + + + P +C G
Sbjct: 425 NLEKNSTKQEILAALEKGCSFLPDPYQKQCDQFVAEYEPVLIEILVEVMDPSFVCLKIGA 484
Query: 758 C 760
C
Sbjct: 485 C 485
Score = 52.0 bits (119), Expect = 6e-06
Identities = 17/35 (48%), Positives = 20/35 (57%)
Frame = +2
Query: 116 LVGNIRCSWGPSYWCSNFSTGRECKATHHCVSRFW 220
L+G +C WGPSYWC N T +C A HC W
Sbjct: 492 LLGTEKCIWGPSYWCQNTETAAQCNAVEHCKRHVW 526
Score = 44.0 bits (99), Expect = 0.001
Identities = 46/203 (22%), Positives = 87/203 (42%), Gaps = 27/203 (13%)
Frame = +2
Query: 236 PEDTDDICKICTDMVKQARDQLESNTT--QEDLKEVFEGSCKLIP-IKVVAKKCMQLADD 406
P+D D+C+ C MV + + +N+T Q ++ V E +L P + + K + +
Sbjct: 191 PKDNGDVCQDCIQMVTDIQTAVRTNSTFVQALVEHVKEECDRLGPGMADICKNYISQYSE 250
Query: 407 FVPELVETLASQMNPNIVCSVAGLCNNYK-----------------IDALLFEYNSQKER 535
+++ + Q P +C++ G C+ K I AL +K
Sbjct: 251 IAIQMMMHMQDQ-QPKEICALVGFCDEVKEMPMQTLVPAKVASKNVIPALELVEPIKKHE 309
Query: 536 V-----VGCNNCQGTVGALRKKFDQTPYE-DFLVGLLKVCRGM-DSLSDSCSMLVFKYYE 694
V V C C+ V + K D E + L K+C + SLS+ C +V Y
Sbjct: 310 VPAKSDVYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLPKSLSEECQEVVDTYGS 369
Query: 695 NIVDAVKKDLTPQSICHVSGQCT 763
+I+ + ++++P+ +C + C+
Sbjct: 370 SILSILLEEVSPELVCSMLHLCS 392
>CR456746-1|CAG33027.1| 524|Homo sapiens PSAP protein.
Length = 524
Score = 87.8 bits (208), Expect = 9e-17
Identities = 43/140 (30%), Positives = 71/140 (50%), Gaps = 1/140 (0%)
Frame = +2
Query: 116 LVGNIRCSWGPSYWCSNFSTGRECKATHHCVSRFWPKYIFPEDTDDICKICTDMVKQARD 295
++G C+ G + WC N T +C A HC+ W K P C IC D+V A D
Sbjct: 19 VLGLKECTRGSAVWCQNVKTASDCGAVKHCLQTVWNK---PTVKSLPCDICKDVVTAAGD 75
Query: 296 QLESNTTQEDLKEVFEGSCKLIPIKVVAKKCMQLADDFVPELVETLASQMN-PNIVCSVA 472
L+ N T+E++ E +C +P ++ C ++ D ++P +++ + +M+ P VCS
Sbjct: 76 MLKDNATEEEILVYLEKTCDWLPKPNMSASCKEIVDSYLPVILDIIKGEMSRPGEVCSAL 135
Query: 473 GLCNNYKIDALLFEYNSQKE 532
LC + + L E N QK+
Sbjct: 136 NLCES--LQKHLAELNHQKQ 153
Score = 83.8 bits (198), Expect = 1e-15
Identities = 42/181 (23%), Positives = 91/181 (50%), Gaps = 2/181 (1%)
Frame = +2
Query: 224 KYIFPEDTDDICKICTDMVKQARDQLESNTTQEDLKEVFEGSCKLIPIKVVAKKCMQLAD 403
K+ P +D C++C +VK+ +++N T++++ + F+ C +P K ++++C ++ D
Sbjct: 304 KHEVPAKSDVYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLP-KSLSEECQEVVD 362
Query: 404 DFVPELVETLASQMNPNIVCSVAGLCNNYKIDALLFEYNSQKERVVGCNNCQGTVGALRK 583
+ + L +++P +VCS+ LC+ ++ AL K+ C C+ VG L +
Sbjct: 363 TYGSSIPSILLEEVSPELVCSMLHLCSGTRLPALTVHVTQPKDGGF-CEVCKKLVGYLDR 421
Query: 584 KFDQ-TPYEDFLVGLLKVCRGM-DSLSDSCSMLVFKYYENIVDAVKKDLTPQSICHVSGQ 757
++ + ++ L L K C + D C V +Y +++ + + + P +C G
Sbjct: 422 NLEKNSTKQEILAALEKGCSFLPDPYQKQCDQFVAEYEPVLIEILVEVMDPSFVCLKIGA 481
Query: 758 C 760
C
Sbjct: 482 C 482
Score = 52.0 bits (119), Expect = 6e-06
Identities = 17/35 (48%), Positives = 20/35 (57%)
Frame = +2
Query: 116 LVGNIRCSWGPSYWCSNFSTGRECKATHHCVSRFW 220
L+G +C WGPSYWC N T +C A HC W
Sbjct: 489 LLGTEKCIWGPSYWCQNTETAAQCNAVEHCKRHVW 523
Score = 45.2 bits (102), Expect = 6e-04
Identities = 48/202 (23%), Positives = 84/202 (41%), Gaps = 26/202 (12%)
Frame = +2
Query: 236 PEDTDDICKICTDMVKQARDQLESNTT--QEDLKEVFEGSCKLIPIKVVAKKCMQLADDF 409
P+D D+C+ C MV + + +N+T Q ++ V E +L P +A C +
Sbjct: 191 PKDNGDVCQDCIQMVTDIQTAVRTNSTFVQALVEHVKEECDRLGP--GMADICKNYISQY 248
Query: 410 VPELVETLASQMNPNIVCSVAGLCNNYK-----------------IDALLFEYNSQKERV 538
E+ + M P +C++ G C+ K I AL +K V
Sbjct: 249 -SEIAIQMMMHMQPKEICALVGFCDEVKEMPMQTLVPAKVASKNVIPALELVEPIKKHEV 307
Query: 539 -----VGCNNCQGTVGALRKKFDQTPYE-DFLVGLLKVCRGM-DSLSDSCSMLVFKYYEN 697
V C C+ V + K D E + L K+C + SLS+ C +V Y +
Sbjct: 308 PAKSDVYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLPKSLSEECQEVVDTYGSS 367
Query: 698 IVDAVKKDLTPQSICHVSGQCT 763
I + ++++P+ +C + C+
Sbjct: 368 IPSILLEEVSPELVCSMLHLCS 389
>BT006849-1|AAP35495.1| 524|Homo sapiens prosaposin (variant
Gaucher disease and variant metachromatic
leukodystrophy) protein.
Length = 524
Score = 87.8 bits (208), Expect = 9e-17
Identities = 43/140 (30%), Positives = 71/140 (50%), Gaps = 1/140 (0%)
Frame = +2
Query: 116 LVGNIRCSWGPSYWCSNFSTGRECKATHHCVSRFWPKYIFPEDTDDICKICTDMVKQARD 295
++G C+ G + WC N T +C A HC+ W K P C IC D+V A D
Sbjct: 19 VLGLKECTRGSAVWCQNVKTASDCGAVKHCLQTVWNK---PTVKSLPCDICKDVVTAAGD 75
Query: 296 QLESNTTQEDLKEVFEGSCKLIPIKVVAKKCMQLADDFVPELVETLASQMN-PNIVCSVA 472
L+ N T+E++ E +C +P ++ C ++ D ++P +++ + +M+ P VCS
Sbjct: 76 MLKDNATEEEILVYLEKTCDWLPKPNMSASCKEIVDSYLPVILDIIKGEMSRPGEVCSAL 135
Query: 473 GLCNNYKIDALLFEYNSQKE 532
LC + + L E N QK+
Sbjct: 136 NLCES--LQKHLAELNHQKQ 153
Score = 85.0 bits (201), Expect = 6e-16
Identities = 42/181 (23%), Positives = 92/181 (50%), Gaps = 2/181 (1%)
Frame = +2
Query: 224 KYIFPEDTDDICKICTDMVKQARDQLESNTTQEDLKEVFEGSCKLIPIKVVAKKCMQLAD 403
K+ P +D C++C +VK+ +++N T++++ + F+ C +P K ++++C ++ D
Sbjct: 304 KHEVPAKSDVYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLP-KSLSEECQEVVD 362
Query: 404 DFVPELVETLASQMNPNIVCSVAGLCNNYKIDALLFEYNSQKERVVGCNNCQGTVGALRK 583
+ ++ L +++P +VCS+ LC+ ++ AL K+ C C+ VG L +
Sbjct: 363 TYGSSILSILLEEVSPELVCSMLHLCSGTRLPALTVHVTQPKDGGF-CEVCKKLVGYLDR 421
Query: 584 KFDQ-TPYEDFLVGLLKVCRGM-DSLSDSCSMLVFKYYENIVDAVKKDLTPQSICHVSGQ 757
++ + ++ L L K C + D C V +Y +++ + + + P +C G
Sbjct: 422 NLEKNSTKQEILAALEKGCSFLPDPYQKQCDQFVAEYEPVLIEILVEVMDPSFVCLKIGA 481
Query: 758 C 760
C
Sbjct: 482 C 482
Score = 52.0 bits (119), Expect = 6e-06
Identities = 17/35 (48%), Positives = 20/35 (57%)
Frame = +2
Query: 116 LVGNIRCSWGPSYWCSNFSTGRECKATHHCVSRFW 220
L+G +C WGPSYWC N T +C A HC W
Sbjct: 489 LLGTEKCIWGPSYWCQNTETAAQCNAVEHCKRHVW 523
Score = 46.4 bits (105), Expect = 3e-04
Identities = 48/202 (23%), Positives = 85/202 (42%), Gaps = 26/202 (12%)
Frame = +2
Query: 236 PEDTDDICKICTDMVKQARDQLESNTT--QEDLKEVFEGSCKLIPIKVVAKKCMQLADDF 409
P+D D+C+ C MV + + +N+T Q ++ V E +L P +A C +
Sbjct: 191 PKDNGDVCQDCIQMVTDIQTAVRTNSTFVQALVEHVKEECDRLGP--GMADICKNYISQY 248
Query: 410 VPELVETLASQMNPNIVCSVAGLCNNYK-----------------IDALLFEYNSQKERV 538
E+ + M P +C++ G C+ K I AL +K V
Sbjct: 249 -SEIAIQMMMHMQPKEICALVGFCDEVKEMPMQTLVPAKVASKNVIPALELVEPIKKHEV 307
Query: 539 -----VGCNNCQGTVGALRKKFDQTPYE-DFLVGLLKVCRGM-DSLSDSCSMLVFKYYEN 697
V C C+ V + K D E + L K+C + SLS+ C +V Y +
Sbjct: 308 PAKSDVYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLPKSLSEECQEVVDTYGSS 367
Query: 698 IVDAVKKDLTPQSICHVSGQCT 763
I+ + ++++P+ +C + C+
Sbjct: 368 ILSILLEEVSPELVCSMLHLCS 389
>BC007612-1|AAH07612.1| 524|Homo sapiens prosaposin (variant
Gaucher disease and variant metachromatic
leukodystrophy) protein.
Length = 524
Score = 87.8 bits (208), Expect = 9e-17
Identities = 43/140 (30%), Positives = 71/140 (50%), Gaps = 1/140 (0%)
Frame = +2
Query: 116 LVGNIRCSWGPSYWCSNFSTGRECKATHHCVSRFWPKYIFPEDTDDICKICTDMVKQARD 295
++G C+ G + WC N T +C A HC+ W K P C IC D+V A D
Sbjct: 19 VLGLKECTRGSAVWCQNVKTASDCGAVKHCLQTVWNK---PTVKSLPCDICKDVVTAAGD 75
Query: 296 QLESNTTQEDLKEVFEGSCKLIPIKVVAKKCMQLADDFVPELVETLASQMN-PNIVCSVA 472
L+ N T+E++ E +C +P ++ C ++ D ++P +++ + +M+ P VCS
Sbjct: 76 MLKDNATEEEILVYLEKTCDWLPKPNMSASCKEIVDSYLPVILDIIKGEMSRPGEVCSAL 135
Query: 473 GLCNNYKIDALLFEYNSQKE 532
LC + + L E N QK+
Sbjct: 136 NLCES--LQKHLAELNHQKQ 153
Score = 85.0 bits (201), Expect = 6e-16
Identities = 42/181 (23%), Positives = 92/181 (50%), Gaps = 2/181 (1%)
Frame = +2
Query: 224 KYIFPEDTDDICKICTDMVKQARDQLESNTTQEDLKEVFEGSCKLIPIKVVAKKCMQLAD 403
K+ P +D C++C +VK+ +++N T++++ + F+ C +P K ++++C ++ D
Sbjct: 304 KHEVPAKSDVYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLP-KSLSEECQEVVD 362
Query: 404 DFVPELVETLASQMNPNIVCSVAGLCNNYKIDALLFEYNSQKERVVGCNNCQGTVGALRK 583
+ ++ L +++P +VCS+ LC+ ++ AL K+ C C+ VG L +
Sbjct: 363 TYGSSILSILLEEVSPELVCSMLHLCSGTRLPALTVHVTQPKDGGF-CEVCKKLVGYLDR 421
Query: 584 KFDQ-TPYEDFLVGLLKVCRGM-DSLSDSCSMLVFKYYENIVDAVKKDLTPQSICHVSGQ 757
++ + ++ L L K C + D C V +Y +++ + + + P +C G
Sbjct: 422 NLEKNSTKQEILAALEKGCSFLPDPYQKQCDQFVAEYEPVLIEILVEVMDPSFVCLKIGA 481
Query: 758 C 760
C
Sbjct: 482 C 482
Score = 52.0 bits (119), Expect = 6e-06
Identities = 17/35 (48%), Positives = 20/35 (57%)
Frame = +2
Query: 116 LVGNIRCSWGPSYWCSNFSTGRECKATHHCVSRFW 220
L+G +C WGPSYWC N T +C A HC W
Sbjct: 489 LLGTEKCIWGPSYWCQNTETAAQCNAVEHCKRHVW 523
Score = 46.4 bits (105), Expect = 3e-04
Identities = 48/202 (23%), Positives = 85/202 (42%), Gaps = 26/202 (12%)
Frame = +2
Query: 236 PEDTDDICKICTDMVKQARDQLESNTT--QEDLKEVFEGSCKLIPIKVVAKKCMQLADDF 409
P+D D+C+ C MV + + +N+T Q ++ V E +L P +A C +
Sbjct: 191 PKDNGDVCQDCIQMVTDIQTAVRTNSTFVQALVEHVKEECDRLGP--GMADICKNYISQY 248
Query: 410 VPELVETLASQMNPNIVCSVAGLCNNYK-----------------IDALLFEYNSQKERV 538
E+ + M P +C++ G C+ K I AL +K V
Sbjct: 249 -SEIAIQMMMHMQPKEICALVGFCDEVKEMPMQTLVPAKVASKNVIPALELVEPIKKHEV 307
Query: 539 -----VGCNNCQGTVGALRKKFDQTPYE-DFLVGLLKVCRGM-DSLSDSCSMLVFKYYEN 697
V C C+ V + K D E + L K+C + SLS+ C +V Y +
Sbjct: 308 PAKSDVYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLPKSLSEECQEVVDTYGSS 367
Query: 698 IVDAVKKDLTPQSICHVSGQCT 763
I+ + ++++P+ +C + C+
Sbjct: 368 ILSILLEEVSPELVCSMLHLCS 389
>BC004275-1|AAH04275.1| 524|Homo sapiens prosaposin (variant
Gaucher disease and variant metachromatic
leukodystrophy) protein.
Length = 524
Score = 87.8 bits (208), Expect = 9e-17
Identities = 43/140 (30%), Positives = 71/140 (50%), Gaps = 1/140 (0%)
Frame = +2
Query: 116 LVGNIRCSWGPSYWCSNFSTGRECKATHHCVSRFWPKYIFPEDTDDICKICTDMVKQARD 295
++G C+ G + WC N T +C A HC+ W K P C IC D+V A D
Sbjct: 19 VLGLKECTRGSAVWCQNVKTASDCGAVKHCLQTVWNK---PTVKSLPCDICKDVVTAAGD 75
Query: 296 QLESNTTQEDLKEVFEGSCKLIPIKVVAKKCMQLADDFVPELVETLASQMN-PNIVCSVA 472
L+ N T+E++ E +C +P ++ C ++ D ++P +++ + +M+ P VCS
Sbjct: 76 MLKDNATEEEILVYLEKTCDWLPKPNMSASCKEIVDSYLPVILDIIKGEMSRPGEVCSAL 135
Query: 473 GLCNNYKIDALLFEYNSQKE 532
LC + + L E N QK+
Sbjct: 136 NLCES--LQKHLAELNHQKQ 153
Score = 85.0 bits (201), Expect = 6e-16
Identities = 42/181 (23%), Positives = 92/181 (50%), Gaps = 2/181 (1%)
Frame = +2
Query: 224 KYIFPEDTDDICKICTDMVKQARDQLESNTTQEDLKEVFEGSCKLIPIKVVAKKCMQLAD 403
K+ P +D C++C +VK+ +++N T++++ + F+ C +P K ++++C ++ D
Sbjct: 304 KHEVPAKSDVYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLP-KSLSEECQEVVD 362
Query: 404 DFVPELVETLASQMNPNIVCSVAGLCNNYKIDALLFEYNSQKERVVGCNNCQGTVGALRK 583
+ ++ L +++P +VCS+ LC+ ++ AL K+ C C+ VG L +
Sbjct: 363 TYGSSILSILLEEVSPELVCSMLHLCSGTRLPALTVHVTQPKDGGF-CEVCKKLVGYLDR 421
Query: 584 KFDQ-TPYEDFLVGLLKVCRGM-DSLSDSCSMLVFKYYENIVDAVKKDLTPQSICHVSGQ 757
++ + ++ L L K C + D C V +Y +++ + + + P +C G
Sbjct: 422 NLEKNSTKQEILAALEKGCSFLPDPYQKQCDQFVAEYEPVLIEILVEVMDPSFVCLKIGA 481
Query: 758 C 760
C
Sbjct: 482 C 482
Score = 52.0 bits (119), Expect = 6e-06
Identities = 17/35 (48%), Positives = 20/35 (57%)
Frame = +2
Query: 116 LVGNIRCSWGPSYWCSNFSTGRECKATHHCVSRFW 220
L+G +C WGPSYWC N T +C A HC W
Sbjct: 489 LLGTEKCIWGPSYWCQNTETAAQCNAVEHCKRHVW 523
Score = 46.4 bits (105), Expect = 3e-04
Identities = 48/202 (23%), Positives = 85/202 (42%), Gaps = 26/202 (12%)
Frame = +2
Query: 236 PEDTDDICKICTDMVKQARDQLESNTT--QEDLKEVFEGSCKLIPIKVVAKKCMQLADDF 409
P+D D+C+ C MV + + +N+T Q ++ V E +L P +A C +
Sbjct: 191 PKDNGDVCQDCIQMVTDIQTAVRTNSTFVQALVEHVKEECDRLGP--GMADICKNYISQY 248
Query: 410 VPELVETLASQMNPNIVCSVAGLCNNYK-----------------IDALLFEYNSQKERV 538
E+ + M P +C++ G C+ K I AL +K V
Sbjct: 249 -SEIAIQMMMHMQPKEICALVGFCDEVKEMPMQTLVPAKVASKNVIPALELVEPIKKHEV 307
Query: 539 -----VGCNNCQGTVGALRKKFDQTPYE-DFLVGLLKVCRGM-DSLSDSCSMLVFKYYEN 697
V C C+ V + K D E + L K+C + SLS+ C +V Y +
Sbjct: 308 PAKSDVYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLPKSLSEECQEVVDTYGSS 367
Query: 698 IVDAVKKDLTPQSICHVSGQCT 763
I+ + ++++P+ +C + C+
Sbjct: 368 ILSILLEEVSPELVCSMLHLCS 389
>BC001503-1|AAH01503.1| 524|Homo sapiens prosaposin (variant
Gaucher disease and variant metachromatic
leukodystrophy) protein.
Length = 524
Score = 87.8 bits (208), Expect = 9e-17
Identities = 43/140 (30%), Positives = 71/140 (50%), Gaps = 1/140 (0%)
Frame = +2
Query: 116 LVGNIRCSWGPSYWCSNFSTGRECKATHHCVSRFWPKYIFPEDTDDICKICTDMVKQARD 295
++G C+ G + WC N T +C A HC+ W K P C IC D+V A D
Sbjct: 19 VLGLKECTRGSAVWCQNVKTASDCGAVKHCLQTVWNK---PTVKSLPCDICKDVVTAAGD 75
Query: 296 QLESNTTQEDLKEVFEGSCKLIPIKVVAKKCMQLADDFVPELVETLASQMN-PNIVCSVA 472
L+ N T+E++ E +C +P ++ C ++ D ++P +++ + +M+ P VCS
Sbjct: 76 MLKDNATEEEILVYLEKTCDWLPKPNMSASCKEIVDSYLPVILDIIKGEMSRPGEVCSAL 135
Query: 473 GLCNNYKIDALLFEYNSQKE 532
LC + + L E N QK+
Sbjct: 136 NLCES--LQKHLAELNHQKQ 153
Score = 85.0 bits (201), Expect = 6e-16
Identities = 42/181 (23%), Positives = 92/181 (50%), Gaps = 2/181 (1%)
Frame = +2
Query: 224 KYIFPEDTDDICKICTDMVKQARDQLESNTTQEDLKEVFEGSCKLIPIKVVAKKCMQLAD 403
K+ P +D C++C +VK+ +++N T++++ + F+ C +P K ++++C ++ D
Sbjct: 304 KHEVPAKSDVYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLP-KSLSEECQEVVD 362
Query: 404 DFVPELVETLASQMNPNIVCSVAGLCNNYKIDALLFEYNSQKERVVGCNNCQGTVGALRK 583
+ ++ L +++P +VCS+ LC+ ++ AL K+ C C+ VG L +
Sbjct: 363 TYGSSILSILLEEVSPELVCSMLHLCSGTRLPALTVHVTQPKDGGF-CEVCKKLVGYLDR 421
Query: 584 KFDQ-TPYEDFLVGLLKVCRGM-DSLSDSCSMLVFKYYENIVDAVKKDLTPQSICHVSGQ 757
++ + ++ L L K C + D C V +Y +++ + + + P +C G
Sbjct: 422 NLEKNSTKQEILAALEKGCSFLPDPYQKQCDQFVAEYEPVLIEILVEVMDPSFVCLKIGA 481
Query: 758 C 760
C
Sbjct: 482 C 482
Score = 52.0 bits (119), Expect = 6e-06
Identities = 17/35 (48%), Positives = 20/35 (57%)
Frame = +2
Query: 116 LVGNIRCSWGPSYWCSNFSTGRECKATHHCVSRFW 220
L+G +C WGPSYWC N T +C A HC W
Sbjct: 489 LLGTEKCIWGPSYWCQNTETAAQCNAVEHCKRHVW 523
Score = 46.4 bits (105), Expect = 3e-04
Identities = 48/202 (23%), Positives = 85/202 (42%), Gaps = 26/202 (12%)
Frame = +2
Query: 236 PEDTDDICKICTDMVKQARDQLESNTT--QEDLKEVFEGSCKLIPIKVVAKKCMQLADDF 409
P+D D+C+ C MV + + +N+T Q ++ V E +L P +A C +
Sbjct: 191 PKDNGDVCQDCIQMVTDIQTAVRTNSTFVQALVEHVKEECDRLGP--GMADICKNYISQY 248
Query: 410 VPELVETLASQMNPNIVCSVAGLCNNYK-----------------IDALLFEYNSQKERV 538
E+ + M P +C++ G C+ K I AL +K V
Sbjct: 249 -SEIAIQMMMHMQPKEICALVGFCDEVKEMPMQTLVPAKVASKNVIPALELVEPIKKHEV 307
Query: 539 -----VGCNNCQGTVGALRKKFDQTPYE-DFLVGLLKVCRGM-DSLSDSCSMLVFKYYEN 697
V C C+ V + K D E + L K+C + SLS+ C +V Y +
Sbjct: 308 PAKSDVYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLPKSLSEECQEVVDTYGSS 367
Query: 698 IVDAVKKDLTPQSICHVSGQCT 763
I+ + ++++P+ +C + C+
Sbjct: 368 ILSILLEEVSPELVCSMLHLCS 389
>AL731541-2|CAI40837.1| 524|Homo sapiens prosaposin (variant
Gaucher disease and variant metachromatic
leukodystrophy) protein.
Length = 524
Score = 87.8 bits (208), Expect = 9e-17
Identities = 43/140 (30%), Positives = 71/140 (50%), Gaps = 1/140 (0%)
Frame = +2
Query: 116 LVGNIRCSWGPSYWCSNFSTGRECKATHHCVSRFWPKYIFPEDTDDICKICTDMVKQARD 295
++G C+ G + WC N T +C A HC+ W K P C IC D+V A D
Sbjct: 19 VLGLKECTRGSAVWCQNVKTASDCGAVKHCLQTVWNK---PTVKSLPCDICKDVVTAAGD 75
Query: 296 QLESNTTQEDLKEVFEGSCKLIPIKVVAKKCMQLADDFVPELVETLASQMN-PNIVCSVA 472
L+ N T+E++ E +C +P ++ C ++ D ++P +++ + +M+ P VCS
Sbjct: 76 MLKDNATEEEILVYLEKTCDWLPKPNMSASCKEIVDSYLPVILDIIKGEMSRPGEVCSAL 135
Query: 473 GLCNNYKIDALLFEYNSQKE 532
LC + + L E N QK+
Sbjct: 136 NLCES--LQKHLAELNHQKQ 153
Score = 85.0 bits (201), Expect = 6e-16
Identities = 42/181 (23%), Positives = 92/181 (50%), Gaps = 2/181 (1%)
Frame = +2
Query: 224 KYIFPEDTDDICKICTDMVKQARDQLESNTTQEDLKEVFEGSCKLIPIKVVAKKCMQLAD 403
K+ P +D C++C +VK+ +++N T++++ + F+ C +P K ++++C ++ D
Sbjct: 304 KHEVPAKSDVYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLP-KSLSEECQEVVD 362
Query: 404 DFVPELVETLASQMNPNIVCSVAGLCNNYKIDALLFEYNSQKERVVGCNNCQGTVGALRK 583
+ ++ L +++P +VCS+ LC+ ++ AL K+ C C+ VG L +
Sbjct: 363 TYGSSILSILLEEVSPELVCSMLHLCSGTRLPALTVHVTQPKDGGF-CEVCKKLVGYLDR 421
Query: 584 KFDQ-TPYEDFLVGLLKVCRGM-DSLSDSCSMLVFKYYENIVDAVKKDLTPQSICHVSGQ 757
++ + ++ L L K C + D C V +Y +++ + + + P +C G
Sbjct: 422 NLEKNSTKQEILAALEKGCSFLPDPYQKQCDQFVAEYEPVLIEILVEVMDPSFVCLKIGA 481
Query: 758 C 760
C
Sbjct: 482 C 482
Score = 52.0 bits (119), Expect = 6e-06
Identities = 17/35 (48%), Positives = 20/35 (57%)
Frame = +2
Query: 116 LVGNIRCSWGPSYWCSNFSTGRECKATHHCVSRFW 220
L+G +C WGPSYWC N T +C A HC W
Sbjct: 489 LLGTEKCIWGPSYWCQNTETAAQCNAVEHCKRHVW 523
Score = 46.4 bits (105), Expect = 3e-04
Identities = 48/202 (23%), Positives = 85/202 (42%), Gaps = 26/202 (12%)
Frame = +2
Query: 236 PEDTDDICKICTDMVKQARDQLESNTT--QEDLKEVFEGSCKLIPIKVVAKKCMQLADDF 409
P+D D+C+ C MV + + +N+T Q ++ V E +L P +A C +
Sbjct: 191 PKDNGDVCQDCIQMVTDIQTAVRTNSTFVQALVEHVKEECDRLGP--GMADICKNYISQY 248
Query: 410 VPELVETLASQMNPNIVCSVAGLCNNYK-----------------IDALLFEYNSQKERV 538
E+ + M P +C++ G C+ K I AL +K V
Sbjct: 249 -SEIAIQMMMHMQPKEICALVGFCDEVKEMPMQTLVPAKVASKNVIPALELVEPIKKHEV 307
Query: 539 -----VGCNNCQGTVGALRKKFDQTPYE-DFLVGLLKVCRGM-DSLSDSCSMLVFKYYEN 697
V C C+ V + K D E + L K+C + SLS+ C +V Y +
Sbjct: 308 PAKSDVYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLPKSLSEECQEVVDTYGSS 367
Query: 698 IVDAVKKDLTPQSICHVSGQCT 763
I+ + ++++P+ +C + C+
Sbjct: 368 ILSILLEEVSPELVCSMLHLCS 389
>AL731541-1|CAI40836.1| 559|Homo sapiens prosaposin (variant
Gaucher disease and variant metachromatic
leukodystrophy) protein.
Length = 559
Score = 87.8 bits (208), Expect = 9e-17
Identities = 43/140 (30%), Positives = 71/140 (50%), Gaps = 1/140 (0%)
Frame = +2
Query: 116 LVGNIRCSWGPSYWCSNFSTGRECKATHHCVSRFWPKYIFPEDTDDICKICTDMVKQARD 295
++G C+ G + WC N T +C A HC+ W K P C IC D+V A D
Sbjct: 19 VLGLKECTRGSAVWCQNVKTASDCGAVKHCLQTVWNK---PTVKSLPCDICKDVVTAAGD 75
Query: 296 QLESNTTQEDLKEVFEGSCKLIPIKVVAKKCMQLADDFVPELVETLASQMN-PNIVCSVA 472
L+ N T+E++ E +C +P ++ C ++ D ++P +++ + +M+ P VCS
Sbjct: 76 MLKDNATEEEILVYLEKTCDWLPKPNMSASCKEIVDSYLPVILDIIKGEMSRPGEVCSAL 135
Query: 473 GLCNNYKIDALLFEYNSQKE 532
LC + + L E N QK+
Sbjct: 136 NLCES--LQKHLAELNHQKQ 153
Score = 85.0 bits (201), Expect = 6e-16
Identities = 42/181 (23%), Positives = 92/181 (50%), Gaps = 2/181 (1%)
Frame = +2
Query: 224 KYIFPEDTDDICKICTDMVKQARDQLESNTTQEDLKEVFEGSCKLIPIKVVAKKCMQLAD 403
K+ P +D C++C +VK+ +++N T++++ + F+ C +P K ++++C ++ D
Sbjct: 304 KHEVPAKSDVYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLP-KSLSEECQEVVD 362
Query: 404 DFVPELVETLASQMNPNIVCSVAGLCNNYKIDALLFEYNSQKERVVGCNNCQGTVGALRK 583
+ ++ L +++P +VCS+ LC+ ++ AL K+ C C+ VG L +
Sbjct: 363 TYGSSILSILLEEVSPELVCSMLHLCSGTRLPALTVHVTQPKDGGF-CEVCKKLVGYLDR 421
Query: 584 KFDQ-TPYEDFLVGLLKVCRGM-DSLSDSCSMLVFKYYENIVDAVKKDLTPQSICHVSGQ 757
++ + ++ L L K C + D C V +Y +++ + + + P +C G
Sbjct: 422 NLEKNSTKQEILAALEKGCSFLPDPYQKQCDQFVAEYEPVLIEILVEVMDPSFVCLKIGA 481
Query: 758 C 760
C
Sbjct: 482 C 482
Score = 52.0 bits (119), Expect = 6e-06
Identities = 17/35 (48%), Positives = 20/35 (57%)
Frame = +2
Query: 116 LVGNIRCSWGPSYWCSNFSTGRECKATHHCVSRFW 220
L+G +C WGPSYWC N T +C A HC W
Sbjct: 489 LLGTEKCIWGPSYWCQNTETAAQCNAVEHCKRHVW 523
Score = 46.4 bits (105), Expect = 3e-04
Identities = 48/202 (23%), Positives = 85/202 (42%), Gaps = 26/202 (12%)
Frame = +2
Query: 236 PEDTDDICKICTDMVKQARDQLESNTT--QEDLKEVFEGSCKLIPIKVVAKKCMQLADDF 409
P+D D+C+ C MV + + +N+T Q ++ V E +L P +A C +
Sbjct: 191 PKDNGDVCQDCIQMVTDIQTAVRTNSTFVQALVEHVKEECDRLGP--GMADICKNYISQY 248
Query: 410 VPELVETLASQMNPNIVCSVAGLCNNYK-----------------IDALLFEYNSQKERV 538
E+ + M P +C++ G C+ K I AL +K V
Sbjct: 249 -SEIAIQMMMHMQPKEICALVGFCDEVKEMPMQTLVPAKVASKNVIPALELVEPIKKHEV 307
Query: 539 -----VGCNNCQGTVGALRKKFDQTPYE-DFLVGLLKVCRGM-DSLSDSCSMLVFKYYEN 697
V C C+ V + K D E + L K+C + SLS+ C +V Y +
Sbjct: 308 PAKSDVYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLPKSLSEECQEVVDTYGSS 367
Query: 698 IVDAVKKDLTPQSICHVSGQCT 763
I+ + ++++P+ +C + C+
Sbjct: 368 ILSILLEEVSPELVCSMLHLCS 389
>AK223290-1|BAD97010.1| 524|Homo sapiens prosaposin (variant
Gaucher disease and variant metachromatic
leukodystrophy) v protein.
Length = 524
Score = 87.8 bits (208), Expect = 9e-17
Identities = 43/140 (30%), Positives = 71/140 (50%), Gaps = 1/140 (0%)
Frame = +2
Query: 116 LVGNIRCSWGPSYWCSNFSTGRECKATHHCVSRFWPKYIFPEDTDDICKICTDMVKQARD 295
++G C+ G + WC N T +C A HC+ W K P C IC D+V A D
Sbjct: 19 VLGLKECTRGSAVWCQNVKTASDCGAVKHCLQTVWNK---PTVKSLPCDICKDVVTAAGD 75
Query: 296 QLESNTTQEDLKEVFEGSCKLIPIKVVAKKCMQLADDFVPELVETLASQMN-PNIVCSVA 472
L+ N T+E++ E +C +P ++ C ++ D ++P +++ + +M+ P VCS
Sbjct: 76 MLKDNATEEEILVYLEKTCDWLPKPNMSASCKEIVDSYLPVILDIIKGEMSRPGEVCSAL 135
Query: 473 GLCNNYKIDALLFEYNSQKE 532
LC + + L E N QK+
Sbjct: 136 NLCES--LQKHLAELNHQKQ 153
Score = 85.0 bits (201), Expect = 6e-16
Identities = 42/181 (23%), Positives = 92/181 (50%), Gaps = 2/181 (1%)
Frame = +2
Query: 224 KYIFPEDTDDICKICTDMVKQARDQLESNTTQEDLKEVFEGSCKLIPIKVVAKKCMQLAD 403
K+ P +D C++C +VK+ +++N T++++ + F+ C +P K ++++C ++ D
Sbjct: 304 KHEVPAKSDVYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLP-KSLSEECQEVVD 362
Query: 404 DFVPELVETLASQMNPNIVCSVAGLCNNYKIDALLFEYNSQKERVVGCNNCQGTVGALRK 583
+ ++ L +++P +VCS+ LC+ ++ AL K+ C C+ VG L +
Sbjct: 363 TYGSSILSILLEEVSPELVCSMLHLCSGTRLPALTVHVTQPKDGGF-CEVCKKLVGYLDR 421
Query: 584 KFDQ-TPYEDFLVGLLKVCRGM-DSLSDSCSMLVFKYYENIVDAVKKDLTPQSICHVSGQ 757
++ + ++ L L K C + D C V +Y +++ + + + P +C G
Sbjct: 422 NLEKNSTKQEILAALEKGCSFLPDPYQKQCDQFVAEYEPVLIEILVEVMDPSFVCLKIGA 481
Query: 758 C 760
C
Sbjct: 482 C 482
Score = 52.0 bits (119), Expect = 6e-06
Identities = 17/35 (48%), Positives = 20/35 (57%)
Frame = +2
Query: 116 LVGNIRCSWGPSYWCSNFSTGRECKATHHCVSRFW 220
L+G +C WGPSYWC N T +C A HC W
Sbjct: 489 LLGTEKCIWGPSYWCQNTETAAQCNAVEHCKRHVW 523
Score = 45.6 bits (103), Expect = 5e-04
Identities = 48/202 (23%), Positives = 85/202 (42%), Gaps = 26/202 (12%)
Frame = +2
Query: 236 PEDTDDICKICTDMVKQARDQLESNTT--QEDLKEVFEGSCKLIPIKVVAKKCMQLADDF 409
P+D D+C+ C MV + + +N+T Q ++ V E +L P +A C +
Sbjct: 191 PKDNGDVCQDCIRMVTDIQTAVRTNSTFVQALVEHVKEECDRLGP--GMADICKNYISQY 248
Query: 410 VPELVETLASQMNPNIVCSVAGLCNNYK-----------------IDALLFEYNSQKERV 538
E+ + M P +C++ G C+ K I AL +K V
Sbjct: 249 -SEIAIQMMMHMQPKEICALVGFCDEVKEMPMQTLVPAKVASKNVIPALELVEPIKKHEV 307
Query: 539 -----VGCNNCQGTVGALRKKFDQTPYE-DFLVGLLKVCRGM-DSLSDSCSMLVFKYYEN 697
V C C+ V + K D E + L K+C + SLS+ C +V Y +
Sbjct: 308 PAKSDVYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLPKSLSEECQEVVDTYGSS 367
Query: 698 IVDAVKKDLTPQSICHVSGQCT 763
I+ + ++++P+ +C + C+
Sbjct: 368 ILSILLEEVSPELVCSMLHLCS 389
>AB209776-1|BAD93013.1| 530|Homo sapiens prosaposin variant
protein.
Length = 530
Score = 87.8 bits (208), Expect = 9e-17
Identities = 43/140 (30%), Positives = 71/140 (50%), Gaps = 1/140 (0%)
Frame = +2
Query: 116 LVGNIRCSWGPSYWCSNFSTGRECKATHHCVSRFWPKYIFPEDTDDICKICTDMVKQARD 295
++G C+ G + WC N T +C A HC+ W K P C IC D+V A D
Sbjct: 22 VLGLKECTRGSAVWCQNVKTASDCGAVKHCLQTVWNK---PTVKSLPCDICKDVVTAAGD 78
Query: 296 QLESNTTQEDLKEVFEGSCKLIPIKVVAKKCMQLADDFVPELVETLASQMN-PNIVCSVA 472
L+ N T+E++ E +C +P ++ C ++ D ++P +++ + +M+ P VCS
Sbjct: 79 MLKDNATEEEILVYLEKTCDWLPKPNMSASCKEIVDSYLPVILDIIKGEMSRPGEVCSAL 138
Query: 473 GLCNNYKIDALLFEYNSQKE 532
LC + + L E N QK+
Sbjct: 139 NLCES--LQKHLAELNHQKQ 156
Score = 85.0 bits (201), Expect = 6e-16
Identities = 42/181 (23%), Positives = 92/181 (50%), Gaps = 2/181 (1%)
Frame = +2
Query: 224 KYIFPEDTDDICKICTDMVKQARDQLESNTTQEDLKEVFEGSCKLIPIKVVAKKCMQLAD 403
K+ P +D C++C +VK+ +++N T++++ + F+ C +P K ++++C ++ D
Sbjct: 310 KHEVPAKSDVYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLP-KSLSEECQEVVD 368
Query: 404 DFVPELVETLASQMNPNIVCSVAGLCNNYKIDALLFEYNSQKERVVGCNNCQGTVGALRK 583
+ ++ L +++P +VCS+ LC+ ++ AL K+ C C+ VG L +
Sbjct: 369 TYGSSILSILLEEVSPELVCSMLHLCSGTRLPALTVHVTQPKDGGF-CEVCKKLVGYLDR 427
Query: 584 KFDQ-TPYEDFLVGLLKVCRGM-DSLSDSCSMLVFKYYENIVDAVKKDLTPQSICHVSGQ 757
++ + ++ L L K C + D C V +Y +++ + + + P +C G
Sbjct: 428 NLEKNSTKQEILAALEKGCSFLPDPYQKQCDQFVAEYEPVLIEILVEVMDPSFVCLKIGA 487
Query: 758 C 760
C
Sbjct: 488 C 488
Score = 52.0 bits (119), Expect = 6e-06
Identities = 17/35 (48%), Positives = 20/35 (57%)
Frame = +2
Query: 116 LVGNIRCSWGPSYWCSNFSTGRECKATHHCVSRFW 220
L+G +C WGPSYWC N T +C A HC W
Sbjct: 495 LLGTEKCIWGPSYWCQNTETAAQCNAVEHCKRHVW 529
Score = 44.0 bits (99), Expect = 0.001
Identities = 46/203 (22%), Positives = 87/203 (42%), Gaps = 27/203 (13%)
Frame = +2
Query: 236 PEDTDDICKICTDMVKQARDQLESNTT--QEDLKEVFEGSCKLIP-IKVVAKKCMQLADD 406
P+D D+C+ C MV + + +N+T Q ++ V E +L P + + K + +
Sbjct: 194 PKDNGDVCQDCIQMVTDIQTAVRTNSTFVQALVEHVKEECDRLGPGMADICKNYISQYSE 253
Query: 407 FVPELVETLASQMNPNIVCSVAGLCNNYK-----------------IDALLFEYNSQKER 535
+++ + Q P +C++ G C+ K I AL +K
Sbjct: 254 IAIQMMMHMQDQ-QPKEICALVGFCDEVKEMPMQTLVPAKVASKNVIPALELVEPIKKHE 312
Query: 536 V-----VGCNNCQGTVGALRKKFDQTPYE-DFLVGLLKVCRGM-DSLSDSCSMLVFKYYE 694
V V C C+ V + K D E + L K+C + SLS+ C +V Y
Sbjct: 313 VPAKSDVYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLPKSLSEECQEVVDTYGS 372
Query: 695 NIVDAVKKDLTPQSICHVSGQCT 763
+I+ + ++++P+ +C + C+
Sbjct: 373 SILSILLEEVSPELVCSMLHLCS 395
>M24461-1|AAB59541.1| 381|Homo sapiens pulmonary
surfactant-associated protein SP-B protein.
Length = 381
Score = 86.2 bits (204), Expect = 3e-16
Identities = 34/133 (25%), Positives = 66/133 (49%)
Frame = +2
Query: 89 LAPTNTKXHLVGNIRCSWGPSYWCSNFSTGRECKATHHCVSRFWPKYIFPEDTDDICKIC 268
L T ++ C+ GP +WC + +C+A HC+ W DD+C+ C
Sbjct: 17 LCGPGTAAWTTSSLACAQGPEFWCQSLEQALQCRALGHCLQEVWGHV----GADDLCQEC 72
Query: 269 TDMVKQARDQLESNTTQEDLKEVFEGSCKLIPIKVVAKKCMQLADDFVPELVETLASQMN 448
D+V + Q+ +++ E C ++P+K++ +C Q+ DD+ P +++ +Q++
Sbjct: 73 EDIVHILNKMAKEAIFQDTMRKFLEQECNVLPLKLLMPQCNQVLDDYFPLVIDYFQNQID 132
Query: 449 PNIVCSVAGLCNN 487
N +C GLC +
Sbjct: 133 SNGICMHLGLCKS 145
>AF400074-1|AAK77913.1| 381|Homo sapiens surfactant,
pulmonary-associated protein B protein.
Length = 381
Score = 86.2 bits (204), Expect = 3e-16
Identities = 34/133 (25%), Positives = 66/133 (49%)
Frame = +2
Query: 89 LAPTNTKXHLVGNIRCSWGPSYWCSNFSTGRECKATHHCVSRFWPKYIFPEDTDDICKIC 268
L T ++ C+ GP +WC + +C+A HC+ W DD+C+ C
Sbjct: 17 LCGPGTAAWTTSSLACAQGPEFWCQSLEQALQCRALGHCLQEVWGHV----GADDLCQEC 72
Query: 269 TDMVKQARDQLESNTTQEDLKEVFEGSCKLIPIKVVAKKCMQLADDFVPELVETLASQMN 448
D+V + Q+ +++ E C ++P+K++ +C Q+ DD+ P +++ +Q++
Sbjct: 73 EDIVHILNKMAKEAIFQDTMRKFLEQECNVLPLKLLMPQCNQVLDDYFPLVIDYFQNQID 132
Query: 449 PNIVCSVAGLCNN 487
N +C GLC +
Sbjct: 133 SNGICMHLGLCKS 145
>J02761-1|AAA60212.1| 381|Homo sapiens pulmonary
surfactant-associated protein SP-B protein.
Length = 381
Score = 85.4 bits (202), Expect = 5e-16
Identities = 34/133 (25%), Positives = 65/133 (48%)
Frame = +2
Query: 89 LAPTNTKXHLVGNIRCSWGPSYWCSNFSTGRECKATHHCVSRFWPKYIFPEDTDDICKIC 268
L T ++ C+ GP +WC + +C+A HC+ W DD+C+ C
Sbjct: 17 LCGPGTAAWTTSSLACAQGPEFWCQSLEQALQCRALGHCLQEVWGHV----GADDLCQEC 72
Query: 269 TDMVKQARDQLESNTTQEDLKEVFEGSCKLIPIKVVAKKCMQLADDFVPELVETLASQMN 448
D+V + Q+ +++ E C ++P+K++ +C Q+ DD+ P +++ +Q +
Sbjct: 73 EDIVHILNKMAKEAIFQDTMRKFLEQECNVLPLKLLMPQCNQVLDDYFPLVIDYFQNQTD 132
Query: 449 PNIVCSVAGLCNN 487
N +C GLC +
Sbjct: 133 SNGICMHLGLCKS 145
>BC032785-1|AAH32785.1| 381|Homo sapiens surfactant,
pulmonary-associated protein B protein.
Length = 381
Score = 85.4 bits (202), Expect = 5e-16
Identities = 34/133 (25%), Positives = 65/133 (48%)
Frame = +2
Query: 89 LAPTNTKXHLVGNIRCSWGPSYWCSNFSTGRECKATHHCVSRFWPKYIFPEDTDDICKIC 268
L T ++ C+ GP +WC + +C+A HC+ W DD+C+ C
Sbjct: 17 LCGPGTAAWTTSSLACAQGPEFWCQSLEQALQCRALGHCLQEVWGHV----GADDLCQEC 72
Query: 269 TDMVKQARDQLESNTTQEDLKEVFEGSCKLIPIKVVAKKCMQLADDFVPELVETLASQMN 448
D+V + Q+ +++ E C ++P+K++ +C Q+ DD+ P +++ +Q +
Sbjct: 73 EDIVHILNKMAKEAIFQDTMRKFLEQECNVLPLKLLMPQCNQVLDDYFPLVIDYFQNQTD 132
Query: 449 PNIVCSVAGLCNN 487
N +C GLC +
Sbjct: 133 SNGICMHLGLCKS 145
>X57108-1|CAA40392.1| 210|Homo sapiens cerebroside sulfate
activator protein.
Length = 210
Score = 85.0 bits (201), Expect = 6e-16
Identities = 42/181 (23%), Positives = 92/181 (50%), Gaps = 2/181 (1%)
Frame = +2
Query: 224 KYIFPEDTDDICKICTDMVKQARDQLESNTTQEDLKEVFEGSCKLIPIKVVAKKCMQLAD 403
K+ P +D C++C +VK+ +++N T++++ + F+ C +P K ++++C ++ D
Sbjct: 1 KHEVPAKSDVYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLP-KSLSEECQEVVD 59
Query: 404 DFVPELVETLASQMNPNIVCSVAGLCNNYKIDALLFEYNSQKERVVGCNNCQGTVGALRK 583
+ ++ L +++P +VCS+ LC+ ++ AL K+ C C+ VG L +
Sbjct: 60 TYGSSILSILLEEVSPELVCSMLHLCSGTRLPALTVHVTQPKDGGF-CEVCKKLVGYLDR 118
Query: 584 KFDQ-TPYEDFLVGLLKVCRGM-DSLSDSCSMLVFKYYENIVDAVKKDLTPQSICHVSGQ 757
++ + ++ L L K C + D C V +Y +++ + + + P +C G
Sbjct: 119 NLEKNSTKQEILAALEKGCSFLPDPYQKQCDQFVAEYEPVLIEILVEVMDPSFVCLKIGA 178
Query: 758 C 760
C
Sbjct: 179 C 179
Score = 40.7 bits (91), Expect = 0.014
Identities = 13/24 (54%), Positives = 16/24 (66%)
Frame = +2
Query: 116 LVGNIRCSWGPSYWCSNFSTGREC 187
L+G +C WGPSYWC N T +C
Sbjct: 186 LLGTEKCIWGPSYWCQNTETAAQC 209
>BC091483-1|AAH91483.1| 240|Homo sapiens PSAP protein protein.
Length = 240
Score = 58.4 bits (135), Expect(2) = 2e-15
Identities = 28/82 (34%), Positives = 41/82 (50%)
Frame = +2
Query: 116 LVGNIRCSWGPSYWCSNFSTGRECKATHHCVSRFWPKYIFPEDTDDICKICTDMVKQARD 295
++G C+ G + WC N T +C A HC+ W K P C IC D+V A D
Sbjct: 19 VLGLKECTRGSAVWCQNVKTASDCGAVKHCLQTVWNK---PTVKSLPCDICKDVVTAAGD 75
Query: 296 QLESNTTQEDLKEVFEGSCKLI 361
L+ N T+E++ E S +L+
Sbjct: 76 MLKDNATEEEILVYLEVSPELV 97
Score = 52.8 bits (121), Expect = 3e-06
Identities = 25/82 (30%), Positives = 41/82 (50%)
Frame = +2
Query: 236 PEDTDDICKICTDMVKQARDQLESNTTQEDLKEVFEGSCKLIPIKVVAKKCMQLADDFVP 415
P+D C++C +V LE N+T++++ E C +P K+C Q ++ P
Sbjct: 119 PKD-GGFCEVCKKLVGYLDRNLEKNSTKQEILAALEKGCSFLP-DPYQKQCDQFVAEYEP 176
Query: 416 ELVETLASQMNPNIVCSVAGLC 481
L+E L M+P+ VC G C
Sbjct: 177 VLIEILVEVMDPSFVCLKIGAC 198
Score = 52.0 bits (119), Expect = 6e-06
Identities = 17/35 (48%), Positives = 20/35 (57%)
Frame = +2
Query: 116 LVGNIRCSWGPSYWCSNFSTGRECKATHHCVSRFW 220
L+G +C WGPSYWC N T +C A HC W
Sbjct: 205 LLGTEKCIWGPSYWCQNTETAAQCNAVEHCKRHVW 239
Score = 45.6 bits (103), Expect(2) = 2e-15
Identities = 26/109 (23%), Positives = 51/109 (46%), Gaps = 2/109 (1%)
Frame = +2
Query: 440 QMNPNIVCSVAGLCNNYKIDALLFEYNSQKERVVGCNNCQGTVGALRKKFDQ-TPYEDFL 616
+++P +VCS+ LC+ ++ AL K+ C C+ VG L + ++ + ++ L
Sbjct: 91 EVSPELVCSMLHLCSGTRLPALTVHVTQPKDGGF-CEVCKKLVGYLDRNLEKNSTKQEIL 149
Query: 617 VGLLKVCRGM-DSLSDSCSMLVFKYYENIVDAVKKDLTPQSICHVSGQC 760
L K C + D C V +Y +++ + + + P +C G C
Sbjct: 150 AALEKGCSFLPDPYQKQCDQFVAEYEPVLIEILVEVMDPSFVCLKIGAC 198
>DQ991252-1|ABJ55983.1| 521|Homo sapiens prosaposin-like protein 1
protein.
Length = 521
Score = 56.0 bits (129), Expect = 3e-07
Identities = 41/179 (22%), Positives = 82/179 (45%), Gaps = 11/179 (6%)
Frame = +2
Query: 257 CKICTDMVKQARDQLESNTTQEDLKEVFEGSCKLIPIKVVAKKCMQLADDFVPELVETLA 436
C++C ++V++ L SN+++ + E C ++P + K+C+ L D + P LV+ L
Sbjct: 294 CEVCMNVVQKLDHWLMSNSSELMITHALERVCSVMPASIT-KECIILVDTYSPSLVQ-LV 351
Query: 437 SQMNPNIVCSVAGLCNNYKI-----DALLF----EYNSQKERVVGCNNCQGTVGALRKKF 589
+++ P VC LC N + DA E++++ + CN C+ +
Sbjct: 352 AKITPEKVCKFIRLCGNRRRARAVHDAYAIVPSPEWDAENQGSF-CNGCKRLLTVSSHNL 410
Query: 590 D-QTPYEDFLVGLLKVCRGMD-SLSDSCSMLVFKYYENIVDAVKKDLTPQSICHVSGQC 760
+ ++ D LV C + C V +Y +++++K + P ++C G C
Sbjct: 411 ESKSTKRDILVAFKGGCSILPLPYMIQCKHFVTQYEPVLIESLKDMMDPVAVCKKVGAC 469
Score = 54.4 bits (125), Expect = 1e-06
Identities = 30/122 (24%), Positives = 50/122 (40%), Gaps = 2/122 (1%)
Frame = +2
Query: 122 GNIRCSWGPSYWCSNFSTGRECKATHHCVSRFWPKYIFPEDTDDICKICTDMVKQARDQL 301
G C+ G + WC + T C A +C W K P C +C D+ A + L
Sbjct: 22 GPQECAKGSTVWCQDLQTAARCGAVGYCQGAVWNK---PTAKSLPCDVCQDIAAAAGNGL 78
Query: 302 ESNTTQEDLKEVFEGSCKLIPIKVVAKKCMQLADDFVPELVETL--ASQMNPNIVCSVAG 475
+ T+ D+ + +C+ +P + + C + D ++ L A P VC+
Sbjct: 79 NPDATESDILALVMKTCEWLPSQESSAGCKWMVDAHSSAILSMLRGAPDSAPAQVCTALS 138
Query: 476 LC 481
LC
Sbjct: 139 LC 140
Score = 54.4 bits (125), Expect = 1e-06
Identities = 23/82 (28%), Positives = 41/82 (50%)
Frame = +2
Query: 239 EDTDDICKICTDMVKQARDQLESNTTQEDLKEVFEGSCKLIPIKVVAKKCMQLADDFVPE 418
E+ C C ++ + LES +T+ D+ F+G C ++P+ + +C + P
Sbjct: 390 ENQGSFCNGCKRLLTVSSHNLESKSTKRDILVAFKGGCSILPLPYMI-QCKHFVTQYEPV 448
Query: 419 LVETLASQMNPNIVCSVAGLCN 484
L+E+L M+P VC G C+
Sbjct: 449 LIESLKDMMDPVAVCKKVGACH 470
Score = 40.7 bits (91), Expect = 0.014
Identities = 13/35 (37%), Positives = 19/35 (54%)
Frame = +2
Query: 116 LVGNIRCSWGPSYWCSNFSTGRECKATHHCVSRFW 220
L+G +C+ GPS+WC + + C A HC W
Sbjct: 476 LLGTDQCALGPSFWCRSQEAAKLCNAVQHCQKHVW 510
>BC068579-1|AAH68579.1| 543|Homo sapiens PSAPL1 protein protein.
Length = 543
Score = 56.0 bits (129), Expect = 3e-07
Identities = 41/179 (22%), Positives = 82/179 (45%), Gaps = 11/179 (6%)
Frame = +2
Query: 257 CKICTDMVKQARDQLESNTTQEDLKEVFEGSCKLIPIKVVAKKCMQLADDFVPELVETLA 436
C++C ++V++ L SN+++ + E C ++P + K+C+ L D + P LV+ L
Sbjct: 316 CEVCMNVVQKLDHWLMSNSSELMITHALERVCSVMPASIT-KECIILVDTYSPSLVQ-LV 373
Query: 437 SQMNPNIVCSVAGLCNNYKI-----DALLF----EYNSQKERVVGCNNCQGTVGALRKKF 589
+++ P VC LC N + DA E++++ + CN C+ +
Sbjct: 374 AKITPEKVCKFIRLCGNRRRARAVHDAYAIVPSPEWDAENQGSF-CNGCKRLLTVSSHNL 432
Query: 590 D-QTPYEDFLVGLLKVCRGMD-SLSDSCSMLVFKYYENIVDAVKKDLTPQSICHVSGQC 760
+ ++ D LV C + C V +Y +++++K + P ++C G C
Sbjct: 433 ESKSTKRDILVAFKGGCSILPLPYMIQCKHFVTQYEPVLIESLKDMMDPVAVCKKVGAC 491
Score = 54.4 bits (125), Expect = 1e-06
Identities = 30/122 (24%), Positives = 50/122 (40%), Gaps = 2/122 (1%)
Frame = +2
Query: 122 GNIRCSWGPSYWCSNFSTGRECKATHHCVSRFWPKYIFPEDTDDICKICTDMVKQARDQL 301
G C+ G + WC + T C A +C W K P C +C D+ A + L
Sbjct: 44 GPQECAKGSTVWCQDLQTAARCGAVGYCQGAVWNK---PTAKSLPCDVCQDIAAAAGNGL 100
Query: 302 ESNTTQEDLKEVFEGSCKLIPIKVVAKKCMQLADDFVPELVETL--ASQMNPNIVCSVAG 475
+ T+ D+ + +C+ +P + + C + D ++ L A P VC+
Sbjct: 101 NPDATESDILALVMKTCEWLPSQESSAGCKWMVDAHSSAILSMLRGAPDSAPAQVCTALS 160
Query: 476 LC 481
LC
Sbjct: 161 LC 162
Score = 54.4 bits (125), Expect = 1e-06
Identities = 23/82 (28%), Positives = 41/82 (50%)
Frame = +2
Query: 239 EDTDDICKICTDMVKQARDQLESNTTQEDLKEVFEGSCKLIPIKVVAKKCMQLADDFVPE 418
E+ C C ++ + LES +T+ D+ F+G C ++P+ + +C + P
Sbjct: 412 ENQGSFCNGCKRLLTVSSHNLESKSTKRDILVAFKGGCSILPLPYMI-QCKHFVTQYEPV 470
Query: 419 LVETLASQMNPNIVCSVAGLCN 484
L+E+L M+P VC G C+
Sbjct: 471 LIESLKDMMDPVAVCKKVGACH 492
Score = 40.7 bits (91), Expect = 0.014
Identities = 13/35 (37%), Positives = 19/35 (54%)
Frame = +2
Query: 116 LVGNIRCSWGPSYWCSNFSTGRECKATHHCVSRFW 220
L+G +C+ GPS+WC + + C A HC W
Sbjct: 498 LLGTDQCALGPSFWCRSQEAAKLCNAVQHCQKHVW 532
>AK097698-1|BAC05143.1| 241|Homo sapiens protein ( Homo sapiens
cDNA FLJ40379 fis, clone TESTI2035262, weakly similar to
PROACTIVATOR POLYPEPTIDE PRECURSOR. ).
Length = 241
Score = 56.0 bits (129), Expect = 3e-07
Identities = 41/179 (22%), Positives = 82/179 (45%), Gaps = 11/179 (6%)
Frame = +2
Query: 257 CKICTDMVKQARDQLESNTTQEDLKEVFEGSCKLIPIKVVAKKCMQLADDFVPELVETLA 436
C++C ++V++ L SN+++ + E C ++P + K+C+ L D + P LV+ L
Sbjct: 26 CEVCMNVVQKLDHWLMSNSSELMITHALERVCSVMPASIT-KECIILVDTYSPSLVQ-LV 83
Query: 437 SQMNPNIVCSVAGLCNNYKI-----DALLF----EYNSQKERVVGCNNCQGTVGALRKKF 589
+++ P VC LC N + DA E++++ + CN C+ +
Sbjct: 84 AKITPEKVCKFIRLCGNRRRARAVHDAYAIVPSPEWDAENQGSF-CNGCKRLLTVSSHNL 142
Query: 590 D-QTPYEDFLVGLLKVCRGMD-SLSDSCSMLVFKYYENIVDAVKKDLTPQSICHVSGQC 760
+ ++ D LV C + C V +Y +++++K + P ++C G C
Sbjct: 143 ESKSTKRDILVAFKGGCSILPLPYMIQCKHFVTQYEPVLIESLKDMMDPVAVCKKVGAC 201
Score = 54.4 bits (125), Expect = 1e-06
Identities = 23/82 (28%), Positives = 41/82 (50%)
Frame = +2
Query: 239 EDTDDICKICTDMVKQARDQLESNTTQEDLKEVFEGSCKLIPIKVVAKKCMQLADDFVPE 418
E+ C C ++ + LES +T+ D+ F+G C ++P+ + +C + P
Sbjct: 122 ENQGSFCNGCKRLLTVSSHNLESKSTKRDILVAFKGGCSILPLPYMI-QCKHFVTQYEPV 180
Query: 419 LVETLASQMNPNIVCSVAGLCN 484
L+E+L M+P VC G C+
Sbjct: 181 LIESLKDMMDPVAVCKKVGACH 202
Score = 37.5 bits (83), Expect = 0.13
Identities = 12/30 (40%), Positives = 18/30 (60%)
Frame = +2
Query: 116 LVGNIRCSWGPSYWCSNFSTGRECKATHHC 205
L+G +C+ GPS+WC + + C A HC
Sbjct: 208 LLGTDQCALGPSFWCRSQEAAKLCNAVQHC 237
>X57107-1|CAA40391.1| 67|Homo sapiens cerebroside sulfate
activator protein.
Length = 67
Score = 48.8 bits (111), Expect = 5e-05
Identities = 18/63 (28%), Positives = 36/63 (57%)
Frame = +2
Query: 257 CKICTDMVKQARDQLESNTTQEDLKEVFEGSCKLIPIKVVAKKCMQLADDFVPELVETLA 436
C IC D+V A D L+ N T+E++ E +C +P ++ C ++ D ++P +++ +
Sbjct: 5 CDICKDVVTAAGDMLKDNATEEEILVYLEKTCDWLPKPNMSASCKEIVDSYLPVILDIIK 64
Query: 437 SQM 445
+M
Sbjct: 65 GEM 67
>M16764-1|AAA88099.1| 286|Homo sapiens pulmonary
surfactant-associated proteolipid protein protein.
Length = 286
Score = 41.9 bits (94), Expect = 0.006
Identities = 14/46 (30%), Positives = 29/46 (63%)
Frame = +2
Query: 350 CKLIPIKVVAKKCMQLADDFVPELVETLASQMNPNIVCSVAGLCNN 487
C ++P+K++ +C Q+ DD+ P +++ +Q + N +C GLC +
Sbjct: 5 CNVLPLKLLMPQCNQVLDDYFPLVIDYFQNQTDSNGICMHLGLCKS 50
Score = 39.5 bits (88), Expect = 0.032
Identities = 32/168 (19%), Positives = 64/168 (38%)
Frame = +2
Query: 257 CKICTDMVKQARDQLESNTTQEDLKEVFEGSCKLIPIKVVAKKCMQLADDFVPELVETLA 436
C +C ++K+ + + + + +V C+++P+ V C LA+ + L++TL
Sbjct: 113 CWLCRALIKRIQAMIPKGALRVAVAQV----CRVVPL-VAGGICQCLAERYSVILLDTLL 167
Query: 437 SQMNPNIVCSVAGLCNNYKIDALLFEYNSQKERVVGCNNCQGTVGALRKKFDQTPYEDFL 616
+M P +VC + C+ R C+ C +Q L
Sbjct: 168 GRMLPQLVCRLVLRCSMDDSAGPRSPTGEWLPRDSECHLCMSVTTQAGNSSEQA----IL 223
Query: 617 VGLLKVCRGMDSLSDSCSMLVFKYYENIVDAVKKDLTPQSICHVSGQC 760
+L+ C G + C V ++ ++ V + + C G C
Sbjct: 224 QAMLQACVGSWLDREKCKQFVEQHTPQLLTLVPRGWDAHTTCQALGVC 271
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 176,086,834
Number of Sequences: 237096
Number of extensions: 3763153
Number of successful extensions: 12538
Number of sequences better than 10.0: 28
Number of HSP's better than 10.0 without gapping: 11689
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 12466
length of database: 76,859,062
effective HSP length: 93
effective length of database: 54,809,134
effective search space used: 22800599744
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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