BLASTX 2.2.12 [Aug-07-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= 030731E7_G07_e631_13.seq (1589 letters) Database: uniref50 1,657,284 sequences; 575,637,011 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value UniRef50_Q7PCV3 Cluster: ENSANGP00000031808; n=9; Endopterygota|... 276 1e-72 UniRef50_Q2LZ66 Cluster: GA19341-PA; n=2; Endopterygota|Rep: GA1... 259 1e-67 UniRef50_P45376 Cluster: Aldose reductase; n=21; Bilateria|Rep: ... 257 5e-67 UniRef50_P15121 Cluster: Aldose reductase; n=72; Eumetazoa|Rep: ... 249 2e-64 UniRef50_Q8CI22 Cluster: 2310005E10Rik protein; n=30; Tetrapoda|... 243 9e-63 UniRef50_Q9VTL0 Cluster: CG6083-PA; n=4; Diptera|Rep: CG6083-PA ... 241 5e-62 UniRef50_UPI00015B56A2 Cluster: PREDICTED: similar to GA10458-PA... 227 5e-58 UniRef50_P14550 Cluster: Alcohol dehydrogenase [NADP+]; n=44; Bi... 226 1e-57 UniRef50_Q9NAI5 Cluster: Putative uncharacterized protein; n=3; ... 218 3e-55 UniRef50_UPI0000588153 Cluster: PREDICTED: hypothetical protein;... 204 7e-51 UniRef50_Q7QK25 Cluster: ENSANGP00000019775; n=2; Anopheles gamb... 204 7e-51 UniRef50_Q0VGY1 Cluster: 3-alpha-hydroxysteroid dehydrogenase; n... 202 3e-50 UniRef50_Q17DN0 Cluster: Aldo-keto reductase; n=5; Culicidae|Rep... 195 3e-48 UniRef50_UPI00015B56A3 Cluster: PREDICTED: similar to aldo-keto ... 192 2e-47 UniRef50_Q2S340 Cluster: Aldehyde reductase; n=10; Bacteria|Rep:... 190 9e-47 UniRef50_A5KSS3 Cluster: Aldehyde reductase; n=1; candidate divi... 190 1e-46 UniRef50_Q8K023 Cluster: Aldo-keto reductase family 1 member C18... 185 2e-45 UniRef50_A2QBD7 Cluster: Catalytic activity: an alcohol + NADP(+... 184 8e-45 UniRef50_UPI000065D0BD Cluster: Homolog of Homo sapiens "AKR1B1 ... 183 1e-44 UniRef50_A7SIT3 Cluster: Predicted protein; n=1; Nematostella ve... 183 1e-44 UniRef50_Q10494 Cluster: Probable oxidoreductase C26F1.07; n=2; ... 182 2e-44 UniRef50_P51857 Cluster: 3-oxo-5-beta-steroid 4-dehydrogenase (E... 182 3e-44 UniRef50_Q7JVH6 Cluster: LD24696p; n=2; Sophophora|Rep: LD24696p... 181 4e-44 UniRef50_UPI0000E4A7CE Cluster: PREDICTED: similar to LOC553452 ... 180 1e-43 UniRef50_Q96JD6-2 Cluster: Isoform 2 of Q96JD6 ; n=4; Catarrhini... 180 1e-43 UniRef50_Q96JD6 Cluster: Aldo-keto reductase family 1 member C-l... 180 1e-43 UniRef50_Q0PGJ6 Cluster: Aldo-keto reductase; n=32; Magnoliophyt... 179 2e-43 UniRef50_P27800 Cluster: Aldehyde reductase 1; n=18; root|Rep: A... 179 2e-43 UniRef50_Q8VC28 Cluster: Aldo-keto reductase family 1 member C13... 179 2e-43 UniRef50_Q54B70 Cluster: Aldehyde reductase; n=2; Dictyostelium ... 178 4e-43 UniRef50_UPI0000E45E29 Cluster: PREDICTED: similar to aldose red... 177 9e-43 UniRef50_Q5BKE9 Cluster: LOC594893 protein; n=5; Xenopus tropica... 175 4e-42 UniRef50_Q96UH3 Cluster: Aldehyde reductase; n=13; Pezizomycotin... 174 5e-42 UniRef50_A4RQH8 Cluster: Predicted protein; n=2; Ostreococcus|Re... 172 2e-41 UniRef50_Q2V420 Cluster: Uncharacterized protein At2g37770.1; n=... 171 6e-41 UniRef50_UPI0000498F1F Cluster: oxidoreductase, aldo/keto reduct... 168 3e-40 UniRef50_Q0IBY6 Cluster: Alcohol dehydrogenase; n=2; Chroococcal... 167 7e-40 UniRef50_UPI0000D9A956 Cluster: PREDICTED: similar to aldo-keto ... 167 9e-40 UniRef50_Q7QVQ9 Cluster: GLP_302_44328_45269; n=1; Giardia lambl... 166 2e-39 UniRef50_A3U9Y0 Cluster: Aldehyde reductase; n=5; Bacteroidetes|... 165 4e-39 UniRef50_A2R6Z3 Cluster: Catalytic activity: an alcohol + NADP(+... 164 5e-39 UniRef50_Q22352 Cluster: Putative uncharacterized protein T08H10... 162 3e-38 UniRef50_Q2UGR1 Cluster: Aldo/keto reductase family proteins; n=... 160 8e-38 UniRef50_A2EYY6 Cluster: Oxidoreductase, aldo/keto reductase fam... 159 2e-37 UniRef50_P38715 Cluster: NADPH-dependent aldose reductase GRE3; ... 159 2e-37 UniRef50_Q1IN88 Cluster: Aldehyde reductase; n=5; Bacteria|Rep: ... 159 2e-37 UniRef50_Q9U2J5 Cluster: Putative uncharacterized protein; n=2; ... 158 4e-37 UniRef50_A2FPE2 Cluster: Oxidoreductase, aldo/keto reductase fam... 158 4e-37 UniRef50_Q4PAT5 Cluster: Putative uncharacterized protein; n=1; ... 157 6e-37 UniRef50_Q8SSK6 Cluster: ALDOSE REDUCTASE; n=1; Encephalitozoon ... 157 1e-36 UniRef50_Q55FL3 Cluster: Aldo-keto reductase; n=2; Dictyostelium... 156 1e-36 UniRef50_Q7ZA52 Cluster: Aldose reductase; n=6; Pezizomycotina|R... 156 2e-36 UniRef50_A2QVE5 Cluster: Similarity: shows similarity to several... 156 2e-36 UniRef50_Q7PLK6 Cluster: CG40064-PA; n=1; Drosophila melanogaste... 155 2e-36 UniRef50_Q7ZWA4 Cluster: Zgc:56622; n=6; cellular organisms|Rep:... 154 5e-36 UniRef50_Q9VHX4 Cluster: CG2767-PA; n=4; Endopterygota|Rep: CG27... 154 5e-36 UniRef50_Q9Y020 Cluster: 3-dehydroecdysone 3beta-reductase precu... 153 1e-35 UniRef50_Q16K66 Cluster: Aldo-keto reductase; n=2; Aedes aegypti... 152 2e-35 UniRef50_A7CWF9 Cluster: Aldehyde reductase; n=2; Bacteria|Rep: ... 151 4e-35 UniRef50_P26690 Cluster: NAD(P)H-dependent 6'-deoxychalcone synt... 151 4e-35 UniRef50_UPI00015B4B22 Cluster: PREDICTED: similar to GA15457-PA... 151 7e-35 UniRef50_A2EHN6 Cluster: Oxidoreductase, aldo/keto reductase fam... 150 1e-34 UniRef50_A7PNI3 Cluster: Chromosome chr1 scaffold_22, whole geno... 149 2e-34 UniRef50_Q17G72 Cluster: Aldo-keto reductase; n=9; Endopterygota... 149 2e-34 UniRef50_Q6RZX1 Cluster: Gld1; n=22; Pezizomycotina|Rep: Gld1 - ... 149 3e-34 UniRef50_UPI000023D0F1 Cluster: hypothetical protein FG03517.1; ... 148 3e-34 UniRef50_Q0CLQ2 Cluster: Putative uncharacterized protein; n=1; ... 146 1e-33 UniRef50_Q1YPE5 Cluster: Aldehyde reductase; n=7; Bacteria|Rep: ... 146 2e-33 UniRef50_Q6CFG7 Cluster: Yarrowia lipolytica chromosome B of str... 146 2e-33 UniRef50_UPI00015B40FA Cluster: PREDICTED: similar to CG2767-PA;... 145 2e-33 UniRef50_Q6C2L0 Cluster: Yarrowia lipolytica chromosome F of str... 145 3e-33 UniRef50_Q03PG5 Cluster: Aldo/keto reductase of diketogulonate r... 144 4e-33 UniRef50_Q1U9L6 Cluster: 2,5-didehydrogluconate reductase; n=3; ... 144 6e-33 UniRef50_A1D4E3 Cluster: D-xylose reductase (Xyl1), putative; n=... 144 6e-33 UniRef50_P28475 Cluster: NADP-dependent D-sorbitol-6-phosphate d... 142 2e-32 UniRef50_Q6TY50 Cluster: Reductase 2; n=10; Magnoliophyta|Rep: R... 142 2e-32 UniRef50_Q5FK98 Cluster: Oxidoreductase; n=8; Lactobacillales|Re... 141 4e-32 UniRef50_Q5KI95 Cluster: Aldo-keto reductase, putative; n=14; Di... 141 4e-32 UniRef50_P23901 Cluster: Aldose reductase; n=9; Poaceae|Rep: Ald... 141 5e-32 UniRef50_Q23320 Cluster: Putative uncharacterized protein; n=4; ... 140 9e-32 UniRef50_UPI0000499B0E Cluster: oxidoreductase, aldo/keto reduct... 140 1e-31 UniRef50_A6W8E7 Cluster: 2,5-didehydrogluconate reductase; n=3; ... 140 1e-31 UniRef50_Q9FJK0 Cluster: Aldose reductase-like protein; n=3; cor... 140 1e-31 UniRef50_Q01J82 Cluster: OSIGBa0152K17.5 protein; n=28; Magnolio... 139 2e-31 UniRef50_Q41399 Cluster: Chalcone reductase; n=4; eudicotyledons... 138 3e-31 UniRef50_Q88SL1 Cluster: Oxidoreductase; n=51; Lactobacillales|R... 138 4e-31 UniRef50_A6WDZ5 Cluster: Aldo/keto reductase; n=5; Bacteria|Rep:... 138 5e-31 UniRef50_Q4FY75 Cluster: Aldo-keto reductase-like protein; n=5; ... 138 5e-31 UniRef50_A2QL02 Cluster: Putative frameshift; n=1; Aspergillus n... 136 2e-30 UniRef50_P14065 Cluster: Protein GCY; n=13; Saccharomycetales|Re... 136 2e-30 UniRef50_UPI0000519CC2 Cluster: PREDICTED: similar to CG2767-PA;... 136 2e-30 UniRef50_A5E082 Cluster: GCY protein; n=4; Saccharomycetales|Rep... 134 5e-30 UniRef50_A3LTU8 Cluster: D-arabinose dehydrogenase; n=5; Sacchar... 134 8e-30 UniRef50_Q8WRT0 Cluster: 3-dehydrecdysone 3b-reductase; n=1; Tri... 132 2e-29 UniRef50_P38115 Cluster: D-arabinose dehydrogenase [NAD(P)+] hea... 132 2e-29 UniRef50_Q5T2L2 Cluster: Aldo-keto reductase family 1 member C-l... 132 2e-29 UniRef50_Q968S3 Cluster: Aldoketoreductase-like protein; n=1; Or... 132 3e-29 UniRef50_P22045 Cluster: Probable reductase; n=101; cellular org... 132 3e-29 UniRef50_Q7N0E4 Cluster: 2,5-diketo-D-gluconic acid reductase A;... 130 8e-29 UniRef50_Q41E86 Cluster: 2,5-didehydrogluconate reductase; n=2; ... 130 8e-29 UniRef50_Q8J0K1 Cluster: 4-dihydromethyltrisporate dehydrogenase... 130 8e-29 UniRef50_Q4Q5N9 Cluster: Prostaglandin f synthase, putative; n=7... 130 1e-28 UniRef50_A6ESC0 Cluster: ARA1; n=1; unidentified eubacterium SCB... 128 5e-28 UniRef50_UPI00015B4912 Cluster: PREDICTED: similar to aldo-keto ... 127 7e-28 UniRef50_Q7PM68 Cluster: ENSANGP00000014386; n=1; Anopheles gamb... 127 7e-28 UniRef50_UPI0000D56CE5 Cluster: PREDICTED: similar to CG6084-PA,... 126 1e-27 UniRef50_Q01HB5 Cluster: OSIGBa0136O08-OSIGBa0153H12.9 protein; ... 126 1e-27 UniRef50_Q7G764 Cluster: Probable NAD(P)H-dependent oxidoreducta... 126 1e-27 UniRef50_Q03TW0 Cluster: Aldo/keto reductase of diketogulonate r... 126 2e-27 UniRef50_Q8ZI40 Cluster: 2,5-diketo-D-gluconic acid reductase A;... 126 2e-27 UniRef50_Q9ZBW7 Cluster: Putative oxidoreductase; n=2; Actinomyc... 125 4e-27 UniRef50_Q7G765 Cluster: Probable NAD(P)H-dependent oxidoreducta... 124 5e-27 UniRef50_P70883 Cluster: AkrI; n=1; Butyrivibrio fibrisolvens|Re... 124 9e-27 UniRef50_Q9HGY0 Cluster: Glycerol dehydrogenase; n=8; Saccharomy... 124 9e-27 UniRef50_Q9X0A2 Cluster: Oxidoreductase, aldo/keto reductase fam... 123 1e-26 UniRef50_Q7VG53 Cluster: Aldo-keto reductase; n=28; Bacteria|Rep... 123 1e-26 UniRef50_Q05KR9 Cluster: Benzil reductase; n=5; Bacillales|Rep: ... 123 1e-26 UniRef50_A6RKL9 Cluster: Putative uncharacterized protein; n=3; ... 123 2e-26 UniRef50_Q03XK0 Cluster: Aldo/keto reductase of diketogulonate r... 122 2e-26 UniRef50_Q7R2T6 Cluster: GLP_291_56367_57278; n=1; Giardia lambl... 122 2e-26 UniRef50_UPI00006CD296 Cluster: oxidoreductase, aldo/keto reduct... 122 3e-26 UniRef50_Q8F1G4 Cluster: Aldehyde reductase; n=8; Bacteria|Rep: ... 122 3e-26 UniRef50_A6NPD6 Cluster: Putative uncharacterized protein; n=3; ... 121 6e-26 UniRef50_Q7XY49 Cluster: Mannose 6-phosphate reductase; n=1; Gri... 121 6e-26 UniRef50_Q4PDR0 Cluster: Putative uncharacterized protein; n=1; ... 121 6e-26 UniRef50_Q6NII7 Cluster: Putative oxidoreductase; n=2; Corynebac... 120 1e-25 UniRef50_A0JRJ3 Cluster: 2,5-didehydrogluconate reductase; n=3; ... 120 1e-25 UniRef50_A7CUW0 Cluster: 2,5-didehydrogluconate reductase; n=6; ... 120 1e-25 UniRef50_Q11BF8 Cluster: Aldo/keto reductase; n=12; Bacteria|Rep... 119 2e-25 UniRef50_A6LZ55 Cluster: 2,5-didehydrogluconate reductase; n=1; ... 119 2e-25 UniRef50_UPI00015B5BD7 Cluster: PREDICTED: similar to aldo-keto ... 119 2e-25 UniRef50_Q68ST9 Cluster: Reductase AKOR2; n=2; Pleurotus djamor|... 119 2e-25 UniRef50_P06632 Cluster: 2,5-diketo-D-gluconic acid reductase A;... 119 2e-25 UniRef50_Q83N50 Cluster: 2,5-diketo-D-gluconic acid reductase; n... 118 3e-25 UniRef50_A7BA05 Cluster: Putative uncharacterized protein; n=1; ... 118 4e-25 UniRef50_Q838E0 Cluster: Oxidoreductase, aldo/keto reductase fam... 117 7e-25 UniRef50_Q9ZUJ6 Cluster: T2K10.1 protein; n=16; core eudicotyled... 117 7e-25 UniRef50_A7P424 Cluster: Chromosome chr1 scaffold_5, whole genom... 117 7e-25 UniRef50_A3C1Z7 Cluster: Putative uncharacterized protein; n=2; ... 117 7e-25 UniRef50_Q5HR31 Cluster: Oxidoreductase, aldo/keto reductase fam... 117 1e-24 UniRef50_Q1VRG6 Cluster: YvgN; n=1; Psychroflexus torquis ATCC 7... 117 1e-24 UniRef50_Q4P4P1 Cluster: Putative uncharacterized protein; n=1; ... 117 1e-24 UniRef50_A7ALH6 Cluster: Putative uncharacterized protein; n=1; ... 116 2e-24 UniRef50_A5PDA8 Cluster: Putative oxidoreductase protein; n=1; E... 114 5e-24 UniRef50_A2UAH0 Cluster: Aldo/keto reductase; n=1; Bacillus coag... 114 7e-24 UniRef50_Q4PHK0 Cluster: Putative uncharacterized protein; n=1; ... 113 1e-23 UniRef50_Q28P63 Cluster: Aldo/keto reductase; n=4; Rhodobacterac... 112 2e-23 UniRef50_Q17DN1 Cluster: Aldo-keto reductase; n=1; Aedes aegypti... 112 2e-23 UniRef50_Q5FT75 Cluster: Putative 2,5-diketo-D-gluconic acid red... 112 3e-23 UniRef50_Q5FLI5 Cluster: Aldehyde reductase; n=2; Bacteria|Rep: ... 112 3e-23 UniRef50_Q24C22 Cluster: Oxidoreductase, aldo/keto reductase fam... 111 5e-23 UniRef50_Q7NB44 Cluster: ARA1; n=3; Firmicutes|Rep: ARA1 - Mycop... 111 6e-23 UniRef50_Q03X85 Cluster: Aldo/keto reductase of diketogulonate r... 110 9e-23 UniRef50_UPI00006CCCD7 Cluster: oxidoreductase, aldo/keto reduct... 110 1e-22 UniRef50_Q890A0 Cluster: Oxidoreductase; n=6; Lactobacillales|Re... 110 1e-22 UniRef50_Q1RFP0 Cluster: 2,5-diketo-D-gluconic acid reductase A;... 109 2e-22 UniRef50_Q5TNP1 Cluster: ENSANGP00000029046; n=2; Culicidae|Rep:... 109 3e-22 UniRef50_A0JRJ6 Cluster: Aldo/keto reductase; n=2; Micrococcinea... 108 3e-22 UniRef50_A0AWM8 Cluster: Aldo/keto reductase; n=4; Actinomycetal... 108 5e-22 UniRef50_Q235V6 Cluster: Oxidoreductase, aldo/keto reductase fam... 107 8e-22 UniRef50_A2QB88 Cluster: Contig An01c0460, complete genome. prec... 107 8e-22 UniRef50_Q8ET73 Cluster: 2,5-diketo-D-gluconate reductase; n=12;... 107 1e-21 UniRef50_Q043M4 Cluster: Aldo/keto reductase of diketogulonate r... 107 1e-21 UniRef50_A0JX62 Cluster: 2,5-didehydrogluconate reductase; n=9; ... 106 1e-21 UniRef50_Q929C8 Cluster: Lin2349 protein; n=12; Listeria|Rep: Li... 106 2e-21 UniRef50_Q5FKI1 Cluster: Reductase-dehydrogenase; n=1; Lactobaci... 106 2e-21 UniRef50_A5AD50 Cluster: Putative uncharacterized protein; n=3; ... 106 2e-21 UniRef50_O13848 Cluster: NADH/NADPH dependent indole-3-acetaldeh... 106 2e-21 UniRef50_UPI00006CA3CB Cluster: oxidoreductase, aldo/keto reduct... 105 2e-21 UniRef50_UPI0000DB6EE9 Cluster: PREDICTED: similar to C35D10.6; ... 105 3e-21 UniRef50_Q4JX70 Cluster: Putative oxidoreductase; n=1; Corynebac... 105 3e-21 UniRef50_P82125 Cluster: 1,5-anhydro-D-fructose reductase; n=1; ... 105 3e-21 UniRef50_Q17568 Cluster: Putative uncharacterized protein; n=1; ... 105 4e-21 UniRef50_Q927E1 Cluster: Lin2848 protein; n=13; Listeria|Rep: Li... 104 6e-21 UniRef50_Q5BLA6 Cluster: Zgc:110782; n=2; Danio rerio|Rep: Zgc:1... 104 7e-21 UniRef50_Q18483 Cluster: Putative uncharacterized protein; n=2; ... 104 7e-21 UniRef50_Q568D7 Cluster: Zgc:110366; n=7; Euteleostomi|Rep: Zgc:... 103 1e-20 UniRef50_Q7WSY4 Cluster: Putative aldo-keto reductase; n=1; Prop... 103 1e-20 UniRef50_A3VHZ9 Cluster: Oxidoreductase; n=1; Rhodobacterales ba... 103 1e-20 UniRef50_Q572D2 Cluster: Aldo-keto reductase, putative; n=1; Phy... 103 1e-20 UniRef50_Q88TV9 Cluster: Oxidoreductase; n=4; Lactobacillus|Rep:... 103 2e-20 UniRef50_Q3E9M9 Cluster: Uncharacterized protein At5g01670.2; n=... 103 2e-20 UniRef50_Q9A2X8 Cluster: Oxidoreductase, aldo/keto reductase fam... 102 2e-20 UniRef50_Q54NR2 Cluster: Aldo-keto reductase; n=3; Dictyostelium... 102 3e-20 UniRef50_A5VK30 Cluster: 2,5-didehydrogluconate reductase; n=2; ... 101 4e-20 UniRef50_P47137 Cluster: Probable oxidoreductase YJR096W; n=8; S... 101 4e-20 UniRef50_Q02198 Cluster: Morphine 6-dehydrogenase; n=5; Bacteria... 101 4e-20 UniRef50_P91997 Cluster: Putative uncharacterized protein; n=4; ... 101 5e-20 UniRef50_A4FEB9 Cluster: 2,5-diketo-D-gluconic acid reductase; n... 101 7e-20 UniRef50_Q5XJM7 Cluster: Zgc:101765; n=5; Eumetazoa|Rep: Zgc:101... 100 1e-19 UniRef50_A1UEC5 Cluster: 2,5-didehydrogluconate reductase; n=20;... 100 1e-19 UniRef50_A5BF24 Cluster: Putative uncharacterized protein; n=1; ... 100 1e-19 UniRef50_A3UJS6 Cluster: Oxidoreductase; n=3; Alphaproteobacteri... 99 2e-19 UniRef50_Q6CEJ0 Cluster: Yarrowia lipolytica chromosome B of str... 99 2e-19 UniRef50_Q7VHE1 Cluster: Putative uncharacterized protein; n=1; ... 99 3e-19 UniRef50_Q0SFM4 Cluster: Probable 2,5-didehydrogluconate reducta... 99 3e-19 UniRef50_A6RMS0 Cluster: Putative uncharacterized protein; n=1; ... 98 6e-19 UniRef50_Q4WP69 Cluster: Aldehyde reductase, putative; n=1; Aspe... 97 9e-19 UniRef50_Q0CK00 Cluster: Predicted protein; n=1; Aspergillus ter... 97 9e-19 UniRef50_Q8G7K9 Cluster: Dehydrogenase or reductase protein; n=4... 97 1e-18 UniRef50_A6VNW9 Cluster: Aldo/keto reductase precursor; n=1; Act... 97 1e-18 UniRef50_Q89JN4 Cluster: Oxidoreductase; n=8; Rhizobiales|Rep: O... 97 1e-18 UniRef50_A7RRF6 Cluster: Predicted protein; n=2; Nematostella ve... 96 2e-18 UniRef50_Q6F7K7 Cluster: 2,5-diketo-D-gluconate reductase; n=20;... 96 3e-18 UniRef50_Q9C1X5 Cluster: Xylose and arabinose reductase; n=1; Sc... 96 3e-18 UniRef50_Q2U219 Cluster: Aldo/keto reductase family proteins; n=... 96 3e-18 UniRef50_Q15NA5 Cluster: Aldo/keto reductase; n=2; Gammaproteoba... 95 3e-18 UniRef50_Q8Y463 Cluster: Lmo2592 protein; n=40; Bacteria|Rep: Lm... 95 5e-18 UniRef50_Q8EUH6 Cluster: Oxidoreductase; n=1; Mycoplasma penetra... 95 6e-18 UniRef50_A4YQ04 Cluster: 2,5-diketo-D-gluconate reductase B; n=1... 95 6e-18 UniRef50_Q1DLF1 Cluster: Putative uncharacterized protein; n=1; ... 95 6e-18 UniRef50_A7D761 Cluster: Aldo/keto reductase; n=2; Halobacteriac... 94 8e-18 UniRef50_A3JU52 Cluster: 2,5-diketo-D-gluconic acid reductase A;... 94 1e-17 UniRef50_Q5UX52 Cluster: Oxidoreductase aldo/keto reductase fami... 94 1e-17 UniRef50_Q5B034 Cluster: Putative uncharacterized protein; n=1; ... 93 1e-17 UniRef50_Q4PE96 Cluster: Putative uncharacterized protein; n=1; ... 93 2e-17 UniRef50_Q5FK99 Cluster: Oxidoreductase aldo-keto reductase fami... 93 2e-17 UniRef50_Q927P9 Cluster: Lin2739 protein; n=12; Bacteria|Rep: Li... 92 3e-17 UniRef50_Q14LU6 Cluster: Putative aldo/keto reductase oxidoreduc... 92 3e-17 UniRef50_Q1Q8W8 Cluster: Aldo/keto reductase; n=1; Psychrobacter... 92 4e-17 UniRef50_A5DRJ6 Cluster: Putative uncharacterized protein; n=4; ... 92 4e-17 UniRef50_A6SI80 Cluster: Putative uncharacterized protein; n=1; ... 91 6e-17 UniRef50_Q09632 Cluster: Probable oxidoreductase ZK1290.5; n=2; ... 91 6e-17 UniRef50_Q8EVT8 Cluster: Oxidoreductase-aldo/keto reductase fami... 91 1e-16 UniRef50_Q9X265 Cluster: Oxidoreductase, aldo/keto reductase fam... 90 1e-16 UniRef50_Q9HM42 Cluster: Alcohol dehydrogenase related protein; ... 90 1e-16 UniRef50_Q4V008 Cluster: Oxidoreductase; n=4; Proteobacteria|Rep... 90 2e-16 UniRef50_Q6WGK4 Cluster: Aldose reductase; n=1; Pristionchus pac... 89 2e-16 UniRef50_Q4DJ59 Cluster: Aldo/keto reductase, putative; n=2; Try... 89 2e-16 UniRef50_Q5V6N9 Cluster: Alcohol dehydrogenase; n=2; Halobacteri... 89 2e-16 UniRef50_A5ZYE6 Cluster: Putative uncharacterized protein; n=1; ... 89 3e-16 UniRef50_Q03U37 Cluster: Aldo/keto reductase of diketogulonate r... 89 4e-16 UniRef50_A7BES9 Cluster: Putative uncharacterized protein; n=1; ... 89 4e-16 UniRef50_A3VRL4 Cluster: Putative uncharacterized protein; n=1; ... 88 5e-16 UniRef50_Q5KD52 Cluster: Oxidoreductase, putative; n=1; Filobasi... 88 5e-16 UniRef50_UPI00005A2CCB Cluster: PREDICTED: similar to Aldose red... 87 9e-16 UniRef50_P15339 Cluster: 2,5-diketo-D-gluconic acid reductase B;... 87 1e-15 UniRef50_Q6U5V3 Cluster: Putative uncharacterized protein; n=1; ... 87 2e-15 UniRef50_A2RMU6 Cluster: Oxidoreductase, aldo/keto reductase fam... 87 2e-15 UniRef50_A0L1A2 Cluster: Aldo/keto reductase; n=8; Gammaproteoba... 87 2e-15 UniRef50_Q4WUF7 Cluster: Aldo-keto reductase, putative; n=3; Pez... 87 2e-15 UniRef50_Q11DV1 Cluster: Aldo/keto reductase; n=10; Alphaproteob... 85 5e-15 UniRef50_O14088 Cluster: Xylose and arabinose reductase; n=1; Sc... 85 5e-15 UniRef50_A7D6Q0 Cluster: Aldo/keto reductase; n=1; Halorubrum la... 85 5e-15 UniRef50_P91021 Cluster: Putative uncharacterized protein; n=1; ... 85 6e-15 UniRef50_Q4P1G1 Cluster: Putative uncharacterized protein; n=1; ... 85 6e-15 UniRef50_Q8ZH36 Cluster: 2,5-diketo-D-gluconic acid reductase B;... 85 6e-15 UniRef50_UPI000155CAC7 Cluster: PREDICTED: hypothetical protein;... 84 9e-15 UniRef50_Q7M4N1 Cluster: Dihydrodiol dehydrogenase DD2; n=2; Hom... 70 1e-14 UniRef50_Q8EVS8 Cluster: Oxidoreductase; n=1; Mycoplasma penetra... 83 1e-14 UniRef50_Q5B5R6 Cluster: Putative uncharacterized protein; n=1; ... 83 1e-14 UniRef50_Q2BBN7 Cluster: YvgN; n=1; Bacillus sp. NRRL B-14911|Re... 83 2e-14 UniRef50_Q1M4Z6 Cluster: Putative aldo-keto reductase/oxidase; n... 83 2e-14 UniRef50_A7TLC4 Cluster: Putative uncharacterized protein; n=1; ... 83 2e-14 UniRef50_Q00XM4 Cluster: Aldo/keto reductase family proteins; n=... 83 3e-14 UniRef50_A6PR52 Cluster: Aldo/keto reductase; n=1; Victivallis v... 82 5e-14 UniRef50_A3WP89 Cluster: Aldo/keto reductase; n=1; Idiomarina ba... 82 5e-14 UniRef50_A3T261 Cluster: Putative uncharacterized protein; n=1; ... 82 5e-14 UniRef50_Q5K8C5 Cluster: Aldo-keto reductase, putative; n=1; Fil... 82 5e-14 UniRef50_Q3CZS2 Cluster: Oxidoreductase, aldo/keto reductase fam... 81 8e-14 UniRef50_Q5V398 Cluster: Oxidoreductase aldo/keto reductase fami... 81 8e-14 UniRef50_Q4Q973 Cluster: Aldo/keto reductase, putative; n=3; Lei... 81 1e-13 UniRef50_Q6L139 Cluster: 2,5-diketo-D-gluconic acid reductase; n... 81 1e-13 UniRef50_Q5UYI9 Cluster: Oxidoreductase; n=1; Haloarcula marismo... 81 1e-13 UniRef50_Q5NLW3 Cluster: Putative oxidoreductase; n=1; Zymomonas... 80 1e-13 UniRef50_Q5V663 Cluster: Aldehyde reductase; n=6; Halobacteriace... 80 1e-13 UniRef50_Q2H7A8 Cluster: Putative uncharacterized protein; n=1; ... 79 2e-13 UniRef50_Q76L37 Cluster: Conjugated polyketone reductase C1; n=3... 79 3e-13 UniRef50_A1CAM7 Cluster: Aldo-keto reductase, putative; n=9; Dik... 79 4e-13 UniRef50_Q9P734 Cluster: Related to 2, 5-diketo-D-gluconic acid ... 78 6e-13 UniRef50_Q68A33 Cluster: Aldo-keto reductase 1a; n=1; Ciona inte... 78 7e-13 UniRef50_Q21274 Cluster: Putative uncharacterized protein; n=1; ... 77 1e-12 UniRef50_Q9P6D3 Cluster: Related to aldo-keto reductase YPR1; n=... 77 1e-12 UniRef50_Q75E75 Cluster: ABL209Cp; n=1; Eremothecium gossypii|Re... 77 1e-12 UniRef50_A4R217 Cluster: Putative uncharacterized protein; n=1; ... 75 5e-12 UniRef50_Q979I4 Cluster: Aldo / keto reductase; n=3; Archaea|Rep... 75 5e-12 UniRef50_Q59Z55 Cluster: Potential aldo/keto reductase; n=6; Sac... 75 7e-12 UniRef50_Q4JCC1 Cluster: 2,5-diketo-D-gluconic acid reductase A;... 75 7e-12 UniRef50_Q1PV10 Cluster: Putative uncharacterized protein; n=1; ... 74 1e-11 UniRef50_Q013C5 Cluster: Glycerol dehydrogenase, putative; n=2; ... 73 2e-11 UniRef50_A7SGW6 Cluster: Predicted protein; n=1; Nematostella ve... 73 2e-11 UniRef50_Q07551 Cluster: NADPH-dependent alpha-keto amide reduct... 73 2e-11 UniRef50_Q61U89 Cluster: Putative uncharacterized protein CBG054... 73 3e-11 UniRef50_A7RUA2 Cluster: Predicted protein; n=1; Nematostella ve... 73 3e-11 UniRef50_Q5KCN9 Cluster: Putative uncharacterized protein; n=1; ... 72 4e-11 UniRef50_Q5FHT2 Cluster: Aldehyde reductase; n=4; Lactobacillus|... 71 8e-11 UniRef50_A3H9Y8 Cluster: Aldo/keto reductase; n=2; Caldivirga ma... 71 8e-11 UniRef50_UPI000038E317 Cluster: hypothetical protein Faci_030017... 70 2e-10 UniRef50_Q11B35 Cluster: Aldo/keto reductase; n=1; Mesorhizobium... 70 2e-10 UniRef50_Q9V2P1 Cluster: Myo-inositol degradation; n=5; Archaea|... 70 2e-10 UniRef50_Q5KKZ8 Cluster: Aldo-keto reductase, putative; n=2; Fil... 69 3e-10 UniRef50_A6QVW8 Cluster: Predicted protein; n=1; Ajellomyces cap... 69 5e-10 UniRef50_Q97U17 Cluster: Oxidoreductase, aldo/keto reductase fam... 68 8e-10 UniRef50_A7D7K7 Cluster: Aldo/keto reductase; n=1; Halorubrum la... 68 8e-10 UniRef50_A7D6I8 Cluster: Aldo/keto reductase; n=1; Halorubrum la... 68 8e-10 UniRef50_A5BYJ4 Cluster: Putative uncharacterized protein; n=1; ... 67 1e-09 UniRef50_Q6CGE9 Cluster: Similar to sp|P47137 Saccharomyces cere... 67 1e-09 UniRef50_Q4WI64 Cluster: Aldehyde reductase, putative; n=22; Pez... 67 1e-09 UniRef50_Q0DHN0 Cluster: Os05g0456200 protein; n=2; Oryza sativa... 66 2e-09 UniRef50_Q89RG2 Cluster: Aldo/keto reductase; n=11; Bacteria|Rep... 66 3e-09 UniRef50_P76234 Cluster: Uncharacterized protein yeaE; n=39; Bac... 66 3e-09 UniRef50_A7PNT1 Cluster: Chromosome chr8 scaffold_23, whole geno... 65 4e-09 UniRef50_Q6CWB9 Cluster: Similarities with sp|Q12458 Saccharomyc... 65 4e-09 UniRef50_A7EW94 Cluster: Putative uncharacterized protein; n=1; ... 65 4e-09 UniRef50_A1RB46 Cluster: 2,5-diketo-D-gluconate reductase; n=1; ... 65 6e-09 UniRef50_Q97UV9 Cluster: Oxidoreductase; n=1; Sulfolobus solfata... 65 6e-09 UniRef50_Q5V1M9 Cluster: Oxidoreductase aldo/keto reductase fami... 64 7e-09 UniRef50_A1S0T5 Cluster: Aldo/keto reductase; n=2; Thermoprotei|... 64 7e-09 UniRef50_Q16CS5 Cluster: 2,5-diketo-D-gluconic acid reductase B,... 64 1e-08 UniRef50_A7LSN6 Cluster: Putative uncharacterized protein; n=3; ... 64 1e-08 UniRef50_Q7NK63 Cluster: Gll1617 protein; n=1; Gloeobacter viola... 64 1e-08 UniRef50_Q64UK5 Cluster: Aldo/keto reductase family oxidoreducta... 63 2e-08 UniRef50_Q2CAL9 Cluster: 2,5-didehydrogluconate reductase; n=2; ... 63 2e-08 UniRef50_Q14LA8 Cluster: Putative aldo/keto reductase oxidoreduc... 63 2e-08 UniRef50_A2G4I3 Cluster: Oxidoreductase, aldo/keto reductase fam... 63 2e-08 UniRef50_UPI000023DF27 Cluster: hypothetical protein FG07276.1; ... 62 4e-08 UniRef50_A3LWP0 Cluster: Aldo/keto reductase; n=7; Saccharomycet... 62 4e-08 UniRef50_Q97V56 Cluster: Dehydrogenase; n=8; Thermoprotei|Rep: D... 62 4e-08 UniRef50_Q76L36 Cluster: Conjugated polyketone reductase C2; n=1... 62 5e-08 UniRef50_A6R5B4 Cluster: NAD(P)H-dependent D-xylose reductase; n... 61 9e-08 UniRef50_Q0GU15 Cluster: ORF28; n=3; Bacteria|Rep: ORF28 - Lacto... 60 1e-07 UniRef50_Q4Q5X1 Cluster: Aldehyde reductase, putative; n=75; cel... 60 1e-07 UniRef50_UPI0001556575 Cluster: PREDICTED: similar to Aldo-keto ... 60 2e-07 UniRef50_A4IJ00 Cluster: LOC548351 protein; n=1; Xenopus tropica... 60 2e-07 UniRef50_A2WWZ1 Cluster: Putative uncharacterized protein; n=1; ... 60 2e-07 UniRef50_A1CLD1 Cluster: Gamma-cysteine synthetase regulatory su... 59 3e-07 UniRef50_Q64W37 Cluster: 2,5-diketo-D-gluconic acid reductase; n... 59 4e-07 UniRef50_Q8DK16 Cluster: Tlr1054 protein; n=6; Cyanobacteria|Rep... 58 8e-07 UniRef50_Q5ZTU6 Cluster: D-xylose reductase III; n=5; Legionella... 57 1e-06 UniRef50_Q9USV2 Cluster: Xylose and arabinose reductase; n=2; Sc... 57 1e-06 UniRef50_Q55ML8 Cluster: Putative uncharacterized protein; n=2; ... 57 1e-06 UniRef50_Q55FL2 Cluster: Putative uncharacterized protein; n=1; ... 56 2e-06 UniRef50_Q4WF80 Cluster: Glycerol dehydrogenase (GCY1), putative... 56 2e-06 UniRef50_Q8ZU65 Cluster: Aldo-keto reductase, putative; n=4; The... 56 2e-06 UniRef50_Q03BE0 Cluster: Aldo/keto reductase family enzyme; n=5;... 56 3e-06 UniRef50_A7HEV1 Cluster: Aldo/keto reductase; n=13; Bacteria|Rep... 56 3e-06 UniRef50_Q18903 Cluster: Putative uncharacterized protein C56G3.... 56 3e-06 UniRef50_A6QXT4 Cluster: Predicted protein; n=1; Ajellomyces cap... 56 3e-06 UniRef50_Q5BC40 Cluster: Putative uncharacterized protein; n=1; ... 54 1e-05 UniRef50_A6SUJ2 Cluster: Uncharacterized conserved protein; n=2;... 54 1e-05 UniRef50_Q016B0 Cluster: COG0667: Predicted oxidoreductases; n=4... 54 1e-05 UniRef50_Q9X0R5 Cluster: Oxidoreductase, aldo/keto reductase fam... 53 2e-05 UniRef50_Q8PN61 Cluster: Oxidoreductase; n=5; Proteobacteria|Rep... 53 2e-05 UniRef50_A6BIJ0 Cluster: Putative uncharacterized protein; n=1; ... 53 2e-05 UniRef50_A2FJN9 Cluster: Putative uncharacterized protein; n=4; ... 53 2e-05 UniRef50_Q6L0T3 Cluster: Oxidoreductase; n=2; Thermoplasmatales|... 52 3e-05 UniRef50_Q8YAN3 Cluster: Lmo0084 protein; n=11; Listeria monocyt... 52 6e-05 UniRef50_A7PU13 Cluster: Chromosome chr7 scaffold_31, whole geno... 52 6e-05 UniRef50_Q59ZT1 Cluster: Putative uncharacterized protein; n=1; ... 52 6e-05 UniRef50_Q2H1Q3 Cluster: Putative uncharacterized protein; n=1; ... 51 7e-05 UniRef50_Q5KKC5 Cluster: Putative uncharacterized protein; n=2; ... 51 1e-04 UniRef50_A1RA11 Cluster: Oxidoreductase, aldo/keto reductase fam... 50 2e-04 UniRef50_Q8UIN0 Cluster: Oxidoreductase; n=3; Alphaproteobacteri... 50 2e-04 UniRef50_Q21EY6 Cluster: Aldo/keto reductase; n=1; Saccharophagu... 50 2e-04 UniRef50_P0A9T5 Cluster: Protein tas; n=88; Bacteria|Rep: Protei... 50 2e-04 UniRef50_UPI0000DAE567 Cluster: hypothetical protein Rgryl_01000... 49 3e-04 UniRef50_UPI000023DA24 Cluster: hypothetical protein FG10036.1; ... 49 3e-04 UniRef50_Q8EUX1 Cluster: Aldo/keto reductase family oxidoreducta... 49 3e-04 UniRef50_Q87SA8 Cluster: Oxidoreductase Tas, aldo/keto reductase... 49 3e-04 UniRef50_Q660Z5 Cluster: Aldose reductase, putative; n=3; Borrel... 49 3e-04 UniRef50_A2UBC7 Cluster: Aldo/keto reductase; n=3; cellular orga... 49 3e-04 UniRef50_Q1IPE6 Cluster: Aldo/keto reductase; n=21; Bacteria|Rep... 49 4e-04 UniRef50_UPI000023DAA9 Cluster: hypothetical protein FG00321.1; ... 48 5e-04 UniRef50_Q2JB77 Cluster: Aldo/keto reductase; n=1; Frankia sp. C... 48 5e-04 UniRef50_Q1U6R9 Cluster: Aldo/keto reductase; n=25; Bacilli|Rep:... 48 5e-04 UniRef50_A7RPK2 Cluster: Predicted protein; n=1; Nematostella ve... 48 5e-04 UniRef50_A3DNU7 Cluster: Aldo/keto reductase; n=3; Desulfurococc... 48 5e-04 UniRef50_UPI00005F9591 Cluster: COG0656: Aldo/keto reductases, r... 48 7e-04 UniRef50_Q6GIV4 Cluster: Aldo/keto reductase family protein; n=1... 48 7e-04 UniRef50_A7HAM2 Cluster: Aldo/keto reductase; n=9; cellular orga... 48 7e-04 UniRef50_Q82JL9 Cluster: Putative oxidoreductase; n=2; Streptomy... 48 0.001 UniRef50_Q2SL81 Cluster: Predicted oxidoreductase; n=10; Bacteri... 48 0.001 UniRef50_Q0UQ60 Cluster: Putative uncharacterized protein; n=1; ... 48 0.001 UniRef50_Q67NQ1 Cluster: Oxidoreductase; n=1; Symbiobacterium th... 47 0.001 UniRef50_A4M6J9 Cluster: Aldo/keto reductase; n=1; Petrotoga mob... 47 0.001 UniRef50_P80874 Cluster: General stress protein 69; n=16; cellul... 47 0.001 UniRef50_Q2JHT1 Cluster: Aldo/keto reductase Tas; n=25; cellular... 47 0.002 UniRef50_Q93KW0 Cluster: Putative oxidoreductase; n=1; Streptomy... 47 0.002 UniRef50_A6W292 Cluster: Aldo/keto reductase; n=9; Bacteria|Rep:... 47 0.002 UniRef50_A1ZPI5 Cluster: Oxidoreductase; n=1; Microscilla marina... 47 0.002 UniRef50_A0YSM3 Cluster: Probable oxidoreductase; n=1; Lyngbya s... 47 0.002 UniRef50_P93818 Cluster: F19P19.12 protein; n=4; Arabidopsis tha... 47 0.002 UniRef50_Q9C2J8 Cluster: Related to D-xylose reductase II, III p... 47 0.002 UniRef50_Q7D001 Cluster: AGR_C_2023p; n=14; Proteobacteria|Rep: ... 46 0.002 UniRef50_Q1IQ78 Cluster: Aldo/keto reductase; n=1; Acidobacteria... 46 0.002 UniRef50_A1B5W4 Cluster: Aldo/keto reductase; n=1; Paracoccus de... 46 0.002 UniRef50_A0LJ47 Cluster: Aldo/keto reductase; n=1; Syntrophobact... 46 0.002 UniRef50_A4QYG8 Cluster: Putative uncharacterized protein; n=1; ... 46 0.002 UniRef50_A0RWV1 Cluster: Oxidoreductase; n=4; Thermoprotei|Rep: ... 37 0.003 UniRef50_A6WAE5 Cluster: Aldo/keto reductase; n=1; Kineococcus r... 46 0.003 UniRef50_A5VEK4 Cluster: Aldo/keto reductase; n=5; Bacteria|Rep:... 46 0.003 UniRef50_A0QHX8 Cluster: General stress protein 69; n=2; Mycobac... 46 0.003 UniRef50_P46905 Cluster: Uncharacterized oxidoreductase yccK; n=... 46 0.003 UniRef50_UPI0000D9C1BD Cluster: PREDICTED: similar to aldo-keto ... 46 0.004 UniRef50_Q98G15 Cluster: Mll3531 protein; n=3; Bacteria|Rep: Mll... 46 0.004 UniRef50_A6X3I0 Cluster: Aldo/keto reductase; n=3; Bacteria|Rep:... 46 0.004 UniRef50_Q872E2 Cluster: Related to gamma-glutamylcysteine synth... 46 0.004 UniRef50_Q60BI7 Cluster: Oxidoreductase, aldo/keto reductase fam... 45 0.005 UniRef50_Q11BU4 Cluster: Aldo/keto reductase; n=11; Proteobacter... 45 0.005 UniRef50_A0QWF1 Cluster: Aldo/keto reductase; n=1; Mycobacterium... 45 0.005 UniRef50_P40690 Cluster: Aldo-keto reductase; n=4; Piroplasmida|... 45 0.005 UniRef50_Q88SS2 Cluster: Oxidoreductase; n=13; Firmicutes|Rep: O... 45 0.006 UniRef50_Q81RN9 Cluster: Oxidoreductase, aldo/keto reductase fam... 45 0.006 UniRef50_A7CVG9 Cluster: Aldo/keto reductase; n=1; Opitutaceae b... 45 0.006 UniRef50_A1RAH7 Cluster: Oxidoreductase, aldo/keto reductase fam... 45 0.006 UniRef50_A0K1H5 Cluster: Aldo/keto reductase; n=6; Actinomycetal... 45 0.006 UniRef50_Q2BBT9 Cluster: Probable oxidoreductase protein; n=2; B... 44 0.008 UniRef50_Q0LP88 Cluster: Aldo/keto reductase; n=4; Bacteria|Rep:... 44 0.008 UniRef50_A7BLU0 Cluster: Aldo/keto reductase family; n=1; Beggia... 44 0.008 UniRef50_Q3I1P2 Cluster: Aldo-keto oxidoreductase; n=6; Bacteria... 44 0.011 UniRef50_Q03I00 Cluster: Aryl-alcohol dehydrogenase related enzy... 44 0.011 UniRef50_UPI00015BB020 Cluster: aldo/keto reductase; n=1; Ignico... 44 0.015 UniRef50_UPI0000447325 Cluster: PREDICTED: similar to aldo-keto ... 44 0.015 UniRef50_A6LWU9 Cluster: Aldo/keto reductase; n=3; Clostridium|R... 44 0.015 UniRef50_O94246 Cluster: Glutamate-cysteine ligase regulatory su... 44 0.015 UniRef50_A7B5J6 Cluster: Putative uncharacterized protein; n=1; ... 43 0.019 UniRef50_UPI0000611A01 Cluster: PREDICTED: similar to MGC80525 p... 43 0.026 UniRef50_A0Q648 Cluster: Aldo/keto reductase family protein; n=1... 43 0.026 UniRef50_Q2H7Q3 Cluster: Putative uncharacterized protein; n=1; ... 43 0.026 UniRef50_A6VXU3 Cluster: Aldo/keto reductase; n=14; Proteobacter... 42 0.034 UniRef50_A5FAZ9 Cluster: Aldo/keto reductase; n=1; Flavobacteriu... 42 0.034 UniRef50_A1GCG3 Cluster: Aldo/keto reductase; n=3; Bacteria|Rep:... 42 0.034 UniRef50_A3H7G3 Cluster: Aldo/keto reductase; n=2; Caldivirga ma... 42 0.034 UniRef50_Q986W6 Cluster: Mlr7180 protein; n=4; Alphaproteobacter... 42 0.045 UniRef50_Q88ZU3 Cluster: Oxidoreductase; n=1; Lactobacillus plan... 42 0.045 UniRef50_Q55493 Cluster: Auxin-induced protein; n=2; Bacteria|Re... 42 0.045 UniRef50_A3U5K6 Cluster: Oxidoreductase, aldo/keto reductase fam... 42 0.045 UniRef50_A0ZMD5 Cluster: Tas; n=1; Nodularia spumigena CCY 9414|... 42 0.045 UniRef50_Q6A7U3 Cluster: Putative oxidoreductase; n=1; Propionib... 42 0.060 UniRef50_Q3WEJ4 Cluster: Aldo/keto reductase; n=9; Bacteria|Rep:... 42 0.060 UniRef50_Q03UP0 Cluster: Aryl-alcohol dehydrogenase family enzym... 42 0.060 UniRef50_A0Y7Y8 Cluster: Aldo/keto reductase; n=1; marine gamma ... 42 0.060 UniRef50_Q034L5 Cluster: Aryl-alcohol dehydrogenase related enzy... 41 0.079 UniRef50_Q01Z07 Cluster: Aldo/keto reductase; n=4; cellular orga... 41 0.079 UniRef50_A7B2Y7 Cluster: Putative uncharacterized protein; n=1; ... 41 0.079 UniRef50_A7T149 Cluster: Predicted protein; n=1; Nematostella ve... 41 0.079 UniRef50_A6SJ74 Cluster: Putative uncharacterized protein; n=1; ... 41 0.079 UniRef50_Q8EVP7 Cluster: Putative oxidoreductase; n=3; Bacteria|... 41 0.10 UniRef50_Q04TM6 Cluster: Aryl-alcohol dehydrogenase-related oxid... 41 0.10 UniRef50_A7DS16 Cluster: Aldo/keto reductase; n=1; Candidatus Ni... 41 0.10 UniRef50_P49261 Cluster: Rho beta-crystallin; n=1; Lepidodactylu... 41 0.10 UniRef50_Q8Y5Q1 Cluster: Lmo2005 protein; n=34; cellular organis... 40 0.14 UniRef50_Q82NW9 Cluster: Putative oxidoreductase; n=3; Streptomy... 40 0.14 UniRef50_Q7NJD8 Cluster: Gll1894 protein; n=5; Bacteria|Rep: Gll... 40 0.14 UniRef50_Q391C9 Cluster: Aldo/keto reductase; n=10; Proteobacter... 40 0.14 UniRef50_Q2AI49 Cluster: Aldo/keto reductase; n=1; Halothermothr... 40 0.14 UniRef50_Q8PVL5 Cluster: Oxidoreductase, ALDO/KETO reductase fam... 40 0.14 UniRef50_Q7UZ40 Cluster: Putative oxidoreductase-possibly Aldo/k... 40 0.18 UniRef50_Q2J7H2 Cluster: Aldo/keto reductase; n=16; Bacteria|Rep... 40 0.18 UniRef50_Q1MJ49 Cluster: Putative general stress protein; n=2; R... 40 0.18 UniRef50_Q0RGM0 Cluster: Putative aldoketoreductase; n=2; Franki... 40 0.18 UniRef50_A6AKU1 Cluster: Aldo/keto reductase; n=2; Gammaproteoba... 40 0.18 UniRef50_A3EV07 Cluster: Putative oxidoreductase; n=1; Leptospir... 40 0.18 UniRef50_A3LSR5 Cluster: D-threo-aldose 1-dehydrogenase; n=5; Sa... 40 0.18 UniRef50_Q8EZ83 Cluster: Aldo/keto reductase family protein; n=1... 40 0.24 UniRef50_Q837G5 Cluster: Oxidoreductase, aldo/keto reductase 2 f... 40 0.24 UniRef50_Q1FHF4 Cluster: Aldo/keto reductase:4Fe-4S ferredoxin, ... 40 0.24 UniRef50_A5Z5D1 Cluster: Putative uncharacterized protein; n=4; ... 40 0.24 UniRef50_A1SGJ5 Cluster: Aldo/keto reductase precursor; n=1; Noc... 40 0.24 UniRef50_A1RJL6 Cluster: Aldo/keto reductase; n=37; Bacteria|Rep... 40 0.24 UniRef50_Q27ST7 Cluster: Oxidoreductase; n=2; Eukaryota|Rep: Oxi... 40 0.24 UniRef50_A0RX58 Cluster: Oxidoreductase; n=1; Cenarchaeum symbio... 40 0.24 UniRef50_Q98IA6 Cluster: Aryl-alcohol dehydrogenase; n=1; Mesorh... 39 0.32 UniRef50_Q025S3 Cluster: Aldo/keto reductase precursor; n=1; Sol... 39 0.32 UniRef50_Q09923 Cluster: Aldo-keto reductase yakc [NADP+]; n=13;... 39 0.32 UniRef50_Q4TC86 Cluster: Chromosome undetermined SCAF7044, whole... 39 0.42 UniRef50_Q98JS9 Cluster: Aldo/keto reductase; n=39; Bacteria|Rep... 39 0.42 UniRef50_Q88TP1 Cluster: Oxidoreductase; n=3; Bacteria|Rep: Oxid... 39 0.42 UniRef50_Q099T4 Cluster: Oxidoreductase; n=2; Proteobacteria|Rep... 39 0.42 UniRef50_A6PQ08 Cluster: Aldo/keto reductase precursor; n=1; Vic... 39 0.42 UniRef50_A6EEC4 Cluster: Putative Norsolorinic acid reductase; n... 39 0.42 UniRef50_Q97UJ7 Cluster: Oxidoreductase; n=4; Archaea|Rep: Oxido... 39 0.42 UniRef50_Q2FGN2 Cluster: Oxidoreductase, aldo/keto reductase fam... 38 0.55 UniRef50_Q4HND9 Cluster: Oxidoreductase, aldo/keto reductase fam... 38 0.55 UniRef50_Q08VS2 Cluster: Twin-arginine translocation pathway sig... 38 0.55 UniRef50_Q08P32 Cluster: Aldo/keto reductase; n=3; Proteobacteri... 38 0.55 UniRef50_A4CIJ8 Cluster: Putative uncharacterized protein; n=2; ... 38 0.55 UniRef50_A1SLH1 Cluster: Aldo/keto reductase; n=27; Bacteria|Rep... 38 0.55 UniRef50_Q33BE9 Cluster: Aldo/keto reductase, putative; n=1; Ory... 38 0.55 UniRef50_Q23TY7 Cluster: Oxidoreductase, aldo/keto reductase fam... 38 0.55 UniRef50_Q89JX0 Cluster: Oxidoreductase; n=26; Bacteria|Rep: Oxi... 38 0.73 UniRef50_Q7NH41 Cluster: Gll2696 protein; n=1; Gloeobacter viola... 38 0.73 UniRef50_Q38Z15 Cluster: Putative aldo/keto reductase; n=2; Bact... 38 0.73 UniRef50_Q08NK7 Cluster: Aldo/keto reductase; n=1; Stigmatella a... 38 0.73 UniRef50_A6DNQ2 Cluster: YqkF; n=1; Lentisphaera araneosa HTCC21... 38 0.73 UniRef50_A1ZSV4 Cluster: Oxidoreductase, aldo/keto reductase fam... 38 0.73 UniRef50_Q9SAC2 Cluster: T16B5.5 protein; n=23; Magnoliophyta|Re... 38 0.73 UniRef50_Q97ZZ1 Cluster: Oxidoreductase; n=4; Sulfolobaceae|Rep:... 38 0.73 UniRef50_A0YC40 Cluster: Putative uncharacterized protein; n=1; ... 38 0.97 UniRef50_Q1JST0 Cluster: Aldo-keto reductase, putative; n=1; Tox... 38 0.97 UniRef50_Q1GHE2 Cluster: Aldo/keto reductase; n=8; Alphaproteoba... 37 1.3 UniRef50_A7HL79 Cluster: Aldo/keto reductase; n=1; Fervidobacter... 37 1.3 UniRef50_A6C9W8 Cluster: Aldo/keto reductase; n=2; Planctomyceta... 37 1.3 UniRef50_A0JTR5 Cluster: Aldo/keto reductase; n=2; Actinomycetal... 37 1.3 UniRef50_A0GDL6 Cluster: Aldo/keto reductase; n=1; Burkholderia ... 37 1.3 UniRef50_Q5ASJ7 Cluster: Putative uncharacterized protein; n=1; ... 37 1.3 UniRef50_P76187 Cluster: Oxidoreductase ydhF; n=51; Gammaproteob... 37 1.3 UniRef50_Q3WFK9 Cluster: Aldo/keto reductase precursor; n=1; Fra... 37 1.7 UniRef50_Q28MK3 Cluster: Aldo/keto reductase; n=19; Alphaproteob... 37 1.7 UniRef50_Q11KU9 Cluster: Twin-arginine translocation pathway sig... 37 1.7 >UniRef50_Q7PCV3 Cluster: ENSANGP00000031808; n=9; Endopterygota|Rep: ENSANGP00000031808 - Anopheles gambiae str. PEST Length = 316 Score = 276 bits (676), Expect = 1e-72 Identities = 136/246 (55%), Positives = 159/246 (64%), Gaps = 1/246 (0%) Frame = +1 Query: 121 VPVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKT 300 VP NG IP+ G+GTW S PG+V QAVKDAID+GYRHI CA VY NE EVGE I Sbjct: 6 VPNAIFKNGNSIPMFGLGTWNSPPGQVAQAVKDAIDVGYRHIDCAHVYQNEHEVGEGIAA 65 Query: 301 KIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDA 480 KI EGVVKREDLF+TSKLWNTFHRPDLV GA + +L+NL +DYLDLYLIHWP Y+E Sbjct: 66 KIAEGVVKREDLFVTSKLWNTFHRPDLVEGACKTTLQNLKLDYLDLYLIHWPVGYQEGTE 125 Query: 481 IFPTDADGK-IQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPGH 657 +FP DGK FSD DYVDTW +E LV GLVR++GVSNFN+KQ+QR+LD A + P Sbjct: 126 LFPMGPDGKTFLFSDADYVDTWPEMEKLVDAGLVRNIGVSNFNAKQVQRVLDVARIPPAT 185 Query: 658 *PGRMPSVFKPXAIEAVLRRP*YYDNGVLPRWGXPDRPWAKPGDPHLMEDPKLKEIADRL 837 I P G P RPW K DP LM+D + ++A + Sbjct: 186 NQIECHPYLHQSKITTFCAEKGIIVTAYSP-LGSPARPWVKADDPVLMDDATVGQLAKKH 244 Query: 838 GKXAAQ 855 GK AAQ Sbjct: 245 GKSAAQ 250 Score = 49.6 bits (113), Expect = 2e-04 Identities = 17/33 (51%), Positives = 25/33 (75%) Frame = +2 Query: 656 TNQVECHPYLNXKRLKQFCEDRDIMITXYSPXG 754 TNQ+ECHPYL+ ++ FC ++ I++T YSP G Sbjct: 185 TNQIECHPYLHQSKITTFCAEKGIIVTAYSPLG 217 >UniRef50_Q2LZ66 Cluster: GA19341-PA; n=2; Endopterygota|Rep: GA19341-PA - Drosophila pseudoobscura (Fruit fly) Length = 315 Score = 259 bits (635), Expect = 1e-67 Identities = 128/251 (50%), Positives = 166/251 (66%), Gaps = 5/251 (1%) Frame = +1 Query: 118 SVPVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIK 297 S P LS+G +P++G+GTW+S P V QAVKDAIDIGYRH CA +YGNE VG AI+ Sbjct: 2 STPSFLLSSGRNMPMVGLGTWRSPPEVVAQAVKDAIDIGYRHFDCAHIYGNELHVGVAIR 61 Query: 298 TKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDD 477 KIQEG+V R++LFITSKLWNTFH+P+LVR A E SLRNL IDYLDLYL+HWP AYK D Sbjct: 62 EKIQEGLVTRDELFITSKLWNTFHKPELVRAACETSLRNLGIDYLDLYLMHWPMAYKSGD 121 Query: 478 AIFPTDAD-GKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPG 654 ++PT D GK F D+DY+DTWKA+E LV GLV ++GVSNFN KQ+ R+L A +KP Sbjct: 122 NLYPTCPDTGKAVFEDIDYLDTWKAMEDLVDSGLVNAIGVSNFNEKQINRLLCLAKLKPV 181 Query: 655 H*PGRMPSVFKPXAIEAVLRRP*YYDNGV----LPRWGXPDRPWAKPGDPHLMEDPKLKE 822 + ++ + YDN + G P+ KPG L+++P + Sbjct: 182 MLQIECHPYLRQKSLITLC-----YDNAIGVTAYSSLGSGHTPYEKPGSYPLLQNPIIVS 236 Query: 823 IADRLGKXAAQ 855 +A++ G+ AQ Sbjct: 237 VAEKYGRTPAQ 247 Score = 38.3 bits (85), Expect = 0.55 Identities = 16/31 (51%), Positives = 18/31 (58%) Frame = +2 Query: 662 QVECHPYLNXKRLKQFCEDRDIMITXYSPXG 754 Q+ECHPYL K L C D I +T YS G Sbjct: 184 QIECHPYLRQKSLITLCYDNAIGVTAYSSLG 214 >UniRef50_P45376 Cluster: Aldose reductase; n=21; Bilateria|Rep: Aldose reductase - Mus musculus (Mouse) Length = 316 Score = 257 bits (630), Expect = 5e-67 Identities = 126/243 (51%), Positives = 164/243 (67%), Gaps = 3/243 (1%) Frame = +1 Query: 136 LSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQEG 315 L+NG K+P +G+GTWKS PG+VT+AVK AID+GYRHI CA VY NEKEVG A++ K++E Sbjct: 7 LNNGTKMPTLGLGTWKSPPGQVTEAVKVAIDLGYRHIDCAQVYQNEKEVGVALQEKLKEQ 66 Query: 316 VVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTD 495 VVKR+DLFI SKLW TFH +V+GA + +L +L +DYLDLYLIHWP +K FP D Sbjct: 67 VVKRQDLFIVSKLWCTFHDKSMVKGAFQKTLSDLQLDYLDLYLIHWPTGFKPGPDYFPLD 126 Query: 496 ADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPGH*PGRMP 675 A G + SD D+VDTW A+E LV GLV+++GVSNFN Q++RIL+ +K + P Sbjct: 127 ASGNVIPSDTDFVDTWTAMEQLVDEGLVKTIGVSNFNPLQIERILNKPGLK--YKPAVNQ 184 Query: 676 SVFKPXAIEAVLRRP*YYDNGVLPRW---GXPDRPWAKPGDPHLMEDPKLKEIADRLGKX 846 P + L + V+ + G PDRPWAKP DP L+EDP++K IA + K Sbjct: 185 IECHPYLTQEKLIEYCHSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAKYNKT 244 Query: 847 AAQ 855 AQ Sbjct: 245 TAQ 247 Score = 47.2 bits (107), Expect = 0.001 Identities = 16/32 (50%), Positives = 24/32 (75%) Frame = +2 Query: 659 NQVECHPYLNXKRLKQFCEDRDIMITXYSPXG 754 NQ+ECHPYL ++L ++C + I++T YSP G Sbjct: 183 NQIECHPYLTQEKLIEYCHSKGIVVTAYSPLG 214 >UniRef50_P15121 Cluster: Aldose reductase; n=72; Eumetazoa|Rep: Aldose reductase - Homo sapiens (Human) Length = 316 Score = 249 bits (609), Expect = 2e-64 Identities = 122/243 (50%), Positives = 162/243 (66%), Gaps = 3/243 (1%) Frame = +1 Query: 136 LSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQEG 315 L+NGAK+P++G+GTWKS PG+VT+AVK AID+GYRHI CA VY NE EVG AI+ K++E Sbjct: 7 LNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLREQ 66 Query: 316 VVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTD 495 VVKRE+LFI SKLW T+H LV+GA + +L +L +DYLDLYLIHWP +K FP D Sbjct: 67 VVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFPLD 126 Query: 496 ADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPGH*PGRMP 675 G + SD + +DTW A+E LV GLV+++G+SNFN Q++ IL+ +K + P Sbjct: 127 ESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLK--YKPAVNQ 184 Query: 676 SVFKPXAIEAVLRRP*YYDNGVLPRW---GXPDRPWAKPGDPHLMEDPKLKEIADRLGKX 846 P + L + V+ + G PDRPWAKP DP L+EDP++K IA + K Sbjct: 185 IECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAKHNKT 244 Query: 847 AAQ 855 AQ Sbjct: 245 TAQ 247 Score = 49.2 bits (112), Expect = 3e-04 Identities = 17/32 (53%), Positives = 25/32 (78%) Frame = +2 Query: 659 NQVECHPYLNXKRLKQFCEDRDIMITXYSPXG 754 NQ+ECHPYL ++L Q+C+ + I++T YSP G Sbjct: 183 NQIECHPYLTQEKLIQYCQSKGIVVTAYSPLG 214 >UniRef50_Q8CI22 Cluster: 2310005E10Rik protein; n=30; Tetrapoda|Rep: 2310005E10Rik protein - Mus musculus (Mouse) Length = 316 Score = 243 bits (595), Expect = 9e-63 Identities = 124/244 (50%), Positives = 160/244 (65%), Gaps = 3/244 (1%) Frame = +1 Query: 133 TLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQE 312 TL GAK+P++G+GTWKS P +V +AVK AID GYRHI CA+VY NE EVGEAI+ KIQE Sbjct: 6 TLLTGAKMPIVGLGTWKSPPAKVREAVKVAIDAGYRHIDCAYVYQNESEVGEAIQEKIQE 65 Query: 313 GVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPT 492 VKREDLFI SKLW+TF LV+ A + +L +L +DYLDLYLIHWPQ ++ + PT Sbjct: 66 KAVKREDLFIVSKLWSTFFEKSLVKKAFQNTLSDLKLDYLDLYLIHWPQGFQSGNVFLPT 125 Query: 493 DADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPGH*PGRM 672 D G I S ++D W+A+E LV GLV++LGVSNFN Q++R+L+ +K H P Sbjct: 126 DDKGSILSSKYTFLDAWEAMEELVDQGLVKALGVSNFNHFQIERLLNKPGLK--HKPVTN 183 Query: 673 PSVFKPXAIEAVLRRP*YYDNGVLPRW---GXPDRPWAKPGDPHLMEDPKLKEIADRLGK 843 P + L + + + + G PDRP AKP DP L+E PK+KEIA + K Sbjct: 184 QVECHPYLTQEKLTQYCHSKGITITAYSPLGSPDRPSAKPEDPLLLEIPKIKEIAAKHKK 243 Query: 844 XAAQ 855 AAQ Sbjct: 244 TAAQ 247 >UniRef50_Q9VTL0 Cluster: CG6083-PA; n=4; Diptera|Rep: CG6083-PA - Drosophila melanogaster (Fruit fly) Length = 322 Score = 241 bits (589), Expect = 5e-62 Identities = 122/252 (48%), Positives = 161/252 (63%), Gaps = 6/252 (2%) Frame = +1 Query: 118 SVPVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIK 297 S P LSNG +P++G+GTW+S P VTQAVKDAIDIGYRH CA +YGNE +VG A++ Sbjct: 2 STPNFLLSNGKNMPMLGLGTWRSPPEVVTQAVKDAIDIGYRHFDCAHIYGNEAQVGAALR 61 Query: 298 TKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKE-D 474 K+ EGVV R++LFITSKLWNT H+PDLVR A E S+RNL + YL+LYL+HWP AYK Sbjct: 62 EKMDEGVVTRDELFITSKLWNTHHKPDLVRPACETSIRNLGVKYLNLYLMHWPMAYKSGS 121 Query: 475 DAIFPTDAD-GKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKP 651 D ++PT D K F D+DYVDTW+A+E LV GL +++GVSNFN +Q+ R+L A +KP Sbjct: 122 DNLYPTCPDTNKAAFEDIDYVDTWRAMENLVDEGLCQAIGVSNFNEQQMNRLLSVAKLKP 181 Query: 652 GH*PGRMPSVFKPXAIEAVLRRP*YYDNGVLPR----WGXPDRPWAKPGDPHLMEDPKLK 819 + + YDN + G P+ KPG L++ P + Sbjct: 182 VVLQIECHPYLSQKPLITLC-----YDNAIAVTAYSCLGSGHTPYEKPGAYPLLQHPTIL 236 Query: 820 EIADRLGKXAAQ 855 IA++ + AAQ Sbjct: 237 AIAEKYERTAAQ 248 Score = 38.7 bits (86), Expect = 0.42 Identities = 17/34 (50%), Positives = 20/34 (58%) Frame = +2 Query: 653 VTNQVECHPYLNXKRLKQFCEDRDIMITXYSPXG 754 V Q+ECHPYL+ K L C D I +T YS G Sbjct: 182 VVLQIECHPYLSQKPLITLCYDNAIAVTAYSCLG 215 >UniRef50_UPI00015B56A2 Cluster: PREDICTED: similar to GA10458-PA; n=2; Nasonia vitripennis|Rep: PREDICTED: similar to GA10458-PA - Nasonia vitripennis Length = 569 Score = 227 bits (556), Expect = 5e-58 Identities = 108/244 (44%), Positives = 158/244 (64%) Frame = +1 Query: 121 VPVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKT 300 VP T ++G K+P+IG+GT+ SKPGEV +AVK AI++GYRH+ AF Y NEKE+G AI+ Sbjct: 3 VPTVTFNDGYKMPMIGLGTFLSKPGEVAEAVKYAIEVGYRHVDTAFFYENEKEIGSAIRE 62 Query: 301 KIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDA 480 KI +G +KRED+F+T+KLW H+ D V A + SL NL DY+DL+L+HWP A+K DA Sbjct: 63 KINDGTIKREDIFVTTKLWCNSHKEDEVVPACKKSLENLGFDYIDLFLVHWPFAFKSGDA 122 Query: 481 IFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPGH* 660 + P DA GKI+FSD DY++TWK +E GL RS+G+SNFNS+Q+ R+L +A +KP + Sbjct: 123 LTPRDAAGKIEFSDTDYLETWKGMEECKRQGLARSIGLSNFNSEQIARLLSSAKIKPVNN 182 Query: 661 PGRMPSVFKPXAIEAVLRRP*YYDNGVLPRWGXPDRPWAKPGDPHLMEDPKLKEIADRLG 840 + + ++ G P RP + G +L ++P+++++A + Sbjct: 183 QVEVTMNLNQKPLIEFCKKHEITVTGFSPL----GRPGNRHGIQNLWDEPQIQKLAQKYK 238 Query: 841 KXAA 852 K A Sbjct: 239 KTPA 242 Score = 150 bits (364), Expect = 9e-35 Identities = 83/208 (39%), Positives = 121/208 (58%), Gaps = 1/208 (0%) Frame = +1 Query: 235 YRHIXCAFVYGNEKEVGEAIKTKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRN 414 YRHI A++Y NEK +G AI+ KI++G VKREDLF+T+KL H+ V A + SL + Sbjct: 301 YRHIDTAYLYDNEKYIGNAIREKIKDGTVKREDLFVTTKLSYYAHKESEVVPACKQSLND 360 Query: 415 LNIDYLDLYLIHWP-QAYKEDDAIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLG 591 L +DY+DLYLIHWP + Y + +A GK+ SD DY++TWK +E GL RS+G Sbjct: 361 LGLDYIDLYLIHWPIRRYFRHN----KNASGKLLLSDTDYLETWKGMEECKRQGLARSIG 416 Query: 592 VSNFNSKQLQRILDNASVKPGH*PGRMPSVFKPXAIEAVLRRP*YYDNGVLPRWGXPDRP 771 VSNFNS+Q+ R+L+ A +KP + + A+ ++ G P RP Sbjct: 417 VSNFNSEQITRLLEAAKIKPVNNQVEVSLKLNQKALIEFCKKHDITVTGYSPL----GRP 472 Query: 772 WAKPGDPHLMEDPKLKEIADRLGKXAAQ 855 + G + +DP ++E+ + GK AQ Sbjct: 473 GNRYGITNAWDDPIIQELVKKYGKTPAQ 500 Score = 35.5 bits (78), Expect = 3.9 Identities = 16/34 (47%), Positives = 21/34 (61%) Frame = +2 Query: 653 VTNQVECHPYLNXKRLKQFCEDRDIMITXYSPXG 754 V NQVE LN K L +FC+ +I +T +SP G Sbjct: 180 VNNQVEVTMNLNQKPLIEFCKKHEITVTGFSPLG 213 >UniRef50_P14550 Cluster: Alcohol dehydrogenase [NADP+]; n=44; Bilateria|Rep: Alcohol dehydrogenase [NADP+] - Homo sapiens (Human) Length = 325 Score = 226 bits (553), Expect = 1e-57 Identities = 112/241 (46%), Positives = 152/241 (63%), Gaps = 1/241 (0%) Frame = +1 Query: 136 LSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQEG 315 L G K+P+IG+GTWKS+PG+V AVK A+ +GYRHI CA +YGNE E+GEA+K + G Sbjct: 8 LHTGQKMPLIGLGTWKSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALKEDVGPG 67 Query: 316 -VVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPT 492 V RE+LF+TSKLWNT H P+ V AL +L +L ++YLDLYL+HWP A++ D FP Sbjct: 68 KAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDNPFPK 127 Query: 493 DADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPGH*PGRM 672 +ADG I + Y +TWKALE LV GLV++LG+SNFNS+Q+ IL ASV+P Sbjct: 128 NADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASVRPAVLQVEC 187 Query: 673 PSVFKPXAIEAVLRRP*YYDNGVLPRWGXPDRPWAKPGDPHLMEDPKLKEIADRLGKXAA 852 + A + P G DR W P +P L+E+P + +A++ G+ A Sbjct: 188 HPYLAQNELIAHCQARGLEVTAYSP-LGSSDRAWRDPDEPVLLEEPVVLALAEKYGRSPA 246 Query: 853 Q 855 Q Sbjct: 247 Q 247 Score = 39.5 bits (88), Expect = 0.24 Identities = 16/31 (51%), Positives = 19/31 (61%) Frame = +2 Query: 662 QVECHPYLNXKRLKQFCEDRDIMITXYSPXG 754 QVECHPYL L C+ R + +T YSP G Sbjct: 184 QVECHPYLAQNELIAHCQARGLEVTAYSPLG 214 >UniRef50_Q9NAI5 Cluster: Putative uncharacterized protein; n=3; Caenorhabditis|Rep: Putative uncharacterized protein - Caenorhabditis elegans Length = 316 Score = 218 bits (533), Expect = 3e-55 Identities = 107/240 (44%), Positives = 144/240 (60%) Frame = +1 Query: 136 LSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQEG 315 L++G IP IG+GTW+SKPGEV A+K A+ GYRHI CA VY N+KEVGEA+K + EG Sbjct: 7 LNSGYSIPAIGLGTWQSKPGEVAAAIKTAVAAGYRHIDCAHVYQNQKEVGEALKEILDEG 66 Query: 316 VVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTD 495 VKRE+LFITSK+WNTFH +++ L +L + Y+DL LIHWPQ Y E +FP Sbjct: 67 KVKREELFITSKVWNTFHSEAKAHENIDIILSDLQLSYVDLMLIHWPQGYAEGAELFPAG 126 Query: 496 ADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPGH*PGRMP 675 +GK+++SDVDY++TWKA E G RS+G+SNF Q+QR+ D A VKP + Sbjct: 127 ENGKMRYSDVDYLETWKAFEAAQKAGKCRSIGLSNFTHSQIQRVWDAAEVKPACLQVELH 186 Query: 676 SVFKPXAIEAVLRRP*YYDNGVLPRWGXPDRPWAKPGDPHLMEDPKLKEIADRLGKXAAQ 855 F + + G P + K GDP+++ + + IA GK AQ Sbjct: 187 PYFTQVKLREFCKEKGIVVVGYSPLGNPGSAFFRKDGDPNVLTNEVVAGIAKAHGKTPAQ 246 >UniRef50_UPI0000588153 Cluster: PREDICTED: hypothetical protein; n=1; Strongylocentrotus purpuratus|Rep: PREDICTED: hypothetical protein - Strongylocentrotus purpuratus Length = 333 Score = 204 bits (497), Expect = 7e-51 Identities = 103/243 (42%), Positives = 143/243 (58%), Gaps = 2/243 (0%) Frame = +1 Query: 133 TLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQE 312 TL +G +P++G+GTWK K EV A+ A+D GYRH CA +YGNEKEVG A++ +Q Sbjct: 6 TLPSGHAMPLVGLGTWKLKADEVAGAIGAAVDAGYRHFDCALIYGNEKEVGVALREAMQR 65 Query: 313 GVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKE--DDAIF 486 +KRED+FIT+K+WNTFH + V SL +L +DY+DLY++HWP ++ +F Sbjct: 66 LGLKREDVFITTKVWNTFHAKEDVAECFNRSLTDLQLDYIDLYIMHWPLGFQNLGPTVMF 125 Query: 487 PTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPGH*PG 666 P G I +SDV Y++TW A+E LV G +SLG+SNFNSKQL +L +++V P Sbjct: 126 PRTETGDIVYSDVHYLETWSAMEDLVKTGKCKSLGLSNFNSKQLDDVLQHSTVPPSVLQV 185 Query: 667 RMPSVFKPXAIEAVLRRP*YYDNGVLPRWGXPDRPWAKPGDPHLMEDPKLKEIADRLGKX 846 + R + P G DR W G+P + +DP L +IA RL K Sbjct: 186 ESHPFLPQVELLNFCRERSVVVSAYSP-LGCGDRAWKLSGEPSIFDDPGLLKIAQRLRKS 244 Query: 847 AAQ 855 AQ Sbjct: 245 IAQ 247 Score = 37.9 bits (84), Expect = 0.73 Identities = 14/31 (45%), Positives = 20/31 (64%) Frame = +2 Query: 662 QVECHPYLNXKRLKQFCEDRDIMITXYSPXG 754 QVE HP+L L FC +R ++++ YSP G Sbjct: 184 QVESHPFLPQVELLNFCRERSVVVSAYSPLG 214 >UniRef50_Q7QK25 Cluster: ENSANGP00000019775; n=2; Anopheles gambiae str. PEST|Rep: ENSANGP00000019775 - Anopheles gambiae str. PEST Length = 319 Score = 204 bits (497), Expect = 7e-51 Identities = 112/252 (44%), Positives = 154/252 (61%), Gaps = 5/252 (1%) Frame = +1 Query: 115 TSVPVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAI 294 T VP SNG +IPV+G GT+ ++ G+ + VK AID+GYRHI AF+Y NE E+G+AI Sbjct: 3 TQVPTVRFSNGYEIPVLGYGTYLAQKGQCVELVKKAIDLGYRHIDTAFLYENEVEIGQAI 62 Query: 295 KTKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYK-- 468 + KI EGV++RED+F+T+KLWNTFH P V A S L+I Y+DL+L+H P + Sbjct: 63 RDKIAEGVIRREDVFVTTKLWNTFHDPQHVEEAFRRSFDMLDIGYIDLFLMHSPMGVQFS 122 Query: 469 --EDDAIFPTDADGKIQFSDVDYVDTWKALEPLV-CHGLVRSLGVSNFNSKQLQRILDNA 639 E + P DA G + FSDVDYV+TWKA+E LV G VRS+G+SNFNS+Q++RIL A Sbjct: 123 GYEYADMQPKDAAGNMLFSDVDYVETWKAMEKLVTAGGRVRSIGLSNFNSEQIERILQIA 182 Query: 640 SVKPGH*PGRMPSVFKPXAIEAVLRRP*YYDNGVLPRWGXPDRPWAKPGDPHLMEDPKLK 819 +VKP + + + A + P G P R G+ + ++DPK+ Sbjct: 183 TVKPVNNQVEANPGYDQRKLIAFCQARGITVTAYGP-MGRPHR--TTNGNRNALDDPKVL 239 Query: 820 EIADRLGKXAAQ 855 EI + GK Q Sbjct: 240 EIGRKYGKTGGQ 251 Score = 36.3 bits (80), Expect = 2.2 Identities = 15/34 (44%), Positives = 21/34 (61%) Frame = +2 Query: 653 VTNQVECHPYLNXKRLKQFCEDRDIMITXYSPXG 754 V NQVE +P + ++L FC+ R I +T Y P G Sbjct: 187 VNNQVEANPGYDQRKLIAFCQARGITVTAYGPMG 220 >UniRef50_Q0VGY1 Cluster: 3-alpha-hydroxysteroid dehydrogenase; n=13; Tetrapoda|Rep: 3-alpha-hydroxysteroid dehydrogenase - Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) Length = 324 Score = 202 bits (492), Expect = 3e-50 Identities = 109/245 (44%), Positives = 142/245 (57%), Gaps = 5/245 (2%) Frame = +1 Query: 136 LSNGAKIPVIGIGTW---KSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKI 306 L++G K+PVIG GT+ K + K AID+GYRHI CAF+YGNE+EVG AI+ KI Sbjct: 11 LNDGHKMPVIGFGTYAPPKFPKSLAEEGTKVAIDVGYRHIDCAFLYGNEEEVGRAIRAKI 70 Query: 307 QEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIF 486 +G VKRED+F T KLW+T H P+ VR ALE SL++L +DY+DL++IH P +K D +F Sbjct: 71 ADGTVKREDVFYTGKLWSTSHTPERVRPALEKSLKDLQLDYMDLFIIHMPMEFKPGDDLF 130 Query: 487 PTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILD--NASVKPGH* 660 P D +GK + + D DTWKALE GLVRS+GVSNFN KQL+ IL+ KP Sbjct: 131 PADENGKFIYHNTDLRDTWKALEKCKDAGLVRSIGVSNFNHKQLELILNMPGLKYKPVCN 190 Query: 661 PGRMPSVFKPXAIEAVLRRP*YYDNGVLPRWGXPDRPWAKPGDPHLMEDPKLKEIADRLG 840 + + G D W + P L+EDP L EIA + Sbjct: 191 QVECHVYLNQSKLLEFCKSKDIVLVGYSVLGSSRDERWIEASTPVLLEDPALTEIAKKHN 250 Query: 841 KXAAQ 855 + AQ Sbjct: 251 RTPAQ 255 Score = 46.0 bits (104), Expect = 0.003 Identities = 18/34 (52%), Positives = 24/34 (70%) Frame = +2 Query: 653 VTNQVECHPYLNXKRLKQFCEDRDIMITXYSPXG 754 V NQVECH YLN +L +FC+ +DI++ YS G Sbjct: 188 VCNQVECHVYLNQSKLLEFCKSKDIVLVGYSVLG 221 >UniRef50_Q17DN0 Cluster: Aldo-keto reductase; n=5; Culicidae|Rep: Aldo-keto reductase - Aedes aegypti (Yellowfever mosquito) Length = 324 Score = 195 bits (475), Expect = 3e-48 Identities = 97/181 (53%), Positives = 124/181 (68%), Gaps = 4/181 (2%) Frame = +1 Query: 121 VPVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKT 300 +P L+NG ++P IG+GT SK E +AV AID G+RHI A+ Y NE VG AI+ Sbjct: 6 IPTVKLNNGLEMPAIGLGTSMSKGDECCKAVMTAIDEGFRHIDTAYNYRNEDVVGRAIRA 65 Query: 301 KIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYK---- 468 KI+EGVV RE+LF+T+KLWNTFH PD V A SL +L +DY+DL+LIH P Y+ Sbjct: 66 KIEEGVVTREELFVTTKLWNTFHHPDHVPMAFGKSLEHLGLDYVDLFLIHMPFGYEFNGW 125 Query: 469 EDDAIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVK 648 + + P D +G + SD DYVDTWKA+E L+ G V S+GVSNFNS+QL+RIL N VK Sbjct: 126 DPEKRTPLDDNGNVLCSDDDYVDTWKAMEKLLESGRVHSIGVSNFNSEQLERILANCRVK 185 Query: 649 P 651 P Sbjct: 186 P 186 Score = 45.6 bits (103), Expect = 0.004 Identities = 19/34 (55%), Positives = 25/34 (73%) Frame = +2 Query: 653 VTNQVECHPYLNXKRLKQFCEDRDIMITXYSPXG 754 VTNQVEC +N K L +FC +RDI++T +SP G Sbjct: 187 VTNQVECSARINQKLLIEFCMERDIVVTAHSPFG 220 >UniRef50_UPI00015B56A3 Cluster: PREDICTED: similar to aldo-keto reductase; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to aldo-keto reductase - Nasonia vitripennis Length = 321 Score = 192 bits (469), Expect = 2e-47 Identities = 88/175 (50%), Positives = 122/175 (69%), Gaps = 2/175 (1%) Frame = +1 Query: 133 TLSNGAKIPVIGIGTWK--SKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKI 306 TLS+G K+PV+G+GTW+ + P EV AVK AID GYRH CA YGNE E+G+AI+ KI Sbjct: 9 TLSDGNKVPVLGLGTWQGGNDPDEVENAVKLAIDAGYRHFDCASFYGNEAEIGKAIQEKI 68 Query: 307 QEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIF 486 +GVVKREDLF+ +K+WN + +LV A + SL+ L + Y+DLYL+HWP +Y Sbjct: 69 DQGVVKREDLFVVTKVWNDERKQELVVAACKRSLKKLGLGYIDLYLVHWPFSYPILYQYI 128 Query: 487 PTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKP 651 + +VDY++TW+ +E + GL RS+GVSNFNS+QL R+L++AS+KP Sbjct: 129 VLPTYNAVTLDEVDYIETWRGMEECIKLGLTRSIGVSNFNSQQLTRLLESASIKP 183 Score = 43.2 bits (97), Expect = 0.019 Identities = 17/34 (50%), Positives = 23/34 (67%) Frame = +2 Query: 653 VTNQVECHPYLNXKRLKQFCEDRDIMITXYSPXG 754 V NQ+E H LN K+L++FC + I +T YSP G Sbjct: 184 VMNQIELHINLNQKKLREFCASKSIAVTGYSPFG 217 >UniRef50_Q2S340 Cluster: Aldehyde reductase; n=10; Bacteria|Rep: Aldehyde reductase - Salinibacter ruber (strain DSM 13855) Length = 321 Score = 190 bits (463), Expect = 9e-47 Identities = 104/243 (42%), Positives = 137/243 (56%), Gaps = 2/243 (0%) Frame = +1 Query: 133 TLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQE 312 + NG ++P+IG+GTWKS PGEV +AV A++ GYRH+ CA +Y NE EVG A+ Sbjct: 5 SFENGDEMPMIGLGTWKSPPGEVYEAVTTALEAGYRHVDCAPIYKNETEVGAALSDSFDA 64 Query: 313 GVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPT 492 G ++R+D+++TSKLWN H PD VR ALE +L +L +D LDLYLIHWP A + + FP Sbjct: 65 GGIRRDDVWVTSKLWNNAHHPDDVRPALEQTLSDLRLDALDLYLIHWPVAL-QPEVDFPE 123 Query: 493 DADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPGH*PGRM 672 D + V +TW A+E L GLVR +GVSNF+ LQ ILD V+P M Sbjct: 124 SPDDFVSPEAVPLTETWAAMEALKKDGLVRHIGVSNFSVPNLQMILDAGEVRPEMNQVEM 183 Query: 673 PSVFKPXAIEAVLRRP*YYDNGVLPRWGXPDRPWAKPGD--PHLMEDPKLKEIADRLGKX 846 + + P G DRP A D P LM +P + +IADR G Sbjct: 184 HPYLPQPELVSFAEAHNIPITAYSP-LGSGDRPDAMKADDEPTLMANPTINDIADRHGVS 242 Query: 847 AAQ 855 AQ Sbjct: 243 PAQ 245 Score = 38.7 bits (86), Expect = 0.42 Identities = 18/32 (56%), Positives = 19/32 (59%) Frame = +2 Query: 659 NQVECHPYLNXKRLKQFCEDRDIMITXYSPXG 754 NQVE HPYL L F E +I IT YSP G Sbjct: 179 NQVEMHPYLPQPELVSFAEAHNIPITAYSPLG 210 >UniRef50_A5KSS3 Cluster: Aldehyde reductase; n=1; candidate division TM7 genomosp. GTL1|Rep: Aldehyde reductase - candidate division TM7 genomosp. GTL1 Length = 299 Score = 190 bits (462), Expect = 1e-46 Identities = 103/241 (42%), Positives = 138/241 (57%) Frame = +1 Query: 133 TLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQE 312 TL N +P++G GTW+ G V+ AI GYRHI CA +YGNEKEVGE I+ I + Sbjct: 5 TLRNKQTLPLLGYGTWELPTGTTADLVETAIKAGYRHIDCAMIYGNEKEVGEGIRRTIDQ 64 Query: 313 GVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPT 492 GVVKREDLF+TSKLWNT H V A +L +L +DYLDLYLIHW A++ D + P Sbjct: 65 GVVKREDLFVTSKLWNTDHAQVDVGVACRKTLNDLGLDYLDLYLIHWGVAFEHGDNLEPL 124 Query: 493 DADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPGH*PGRM 672 D DG +FS + +TW+A+E LV GLV+S+GV+NF + L +L A +KP + Sbjct: 125 DDDGVAKFSFISMKETWQAMEELVEQGLVKSMGVANFTAPMLLDLLSYAKIKPAVHQIEL 184 Query: 673 PSVFKPXAIEAVLRRP*YYDNGVLPRWGXPDRPWAKPGDPHLMEDPKLKEIADRLGKXAA 852 + A Y N + + P+ P ++ DP +KE+A LGK A Sbjct: 185 HPYLAQNDLVAFC----YSQNIAVTAYS----PFGSTEAP-VLTDPTVKEVAKGLGKTPA 235 Query: 853 Q 855 Q Sbjct: 236 Q 236 Score = 37.5 bits (83), Expect = 0.97 Identities = 15/32 (46%), Positives = 20/32 (62%) Frame = +2 Query: 659 NQVECHPYLNXKRLKQFCEDRDIMITXYSPXG 754 +Q+E HPYL L FC ++I +T YSP G Sbjct: 180 HQIELHPYLAQNDLVAFCYSQNIAVTAYSPFG 211 >UniRef50_Q8K023 Cluster: Aldo-keto reductase family 1 member C18; n=72; Tetrapoda|Rep: Aldo-keto reductase family 1 member C18 - Mus musculus (Mouse) Length = 323 Score = 185 bits (451), Expect = 2e-45 Identities = 86/174 (49%), Positives = 124/174 (71%), Gaps = 3/174 (1%) Frame = +1 Query: 136 LSNGAKIPVIGIGTWKSKPG---EVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKI 306 L++G IPV+G GT+ ++ + ++ K AID+G+ HI C+ +Y NE+E+G+AI +KI Sbjct: 10 LNDGHSIPVLGFGTYATEEHLKKKSMESTKIAIDVGFCHIDCSHLYQNEEEIGQAILSKI 69 Query: 307 QEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIF 486 ++G VKRED+F TSKLW+T HRP+LVR +LE SLR LN+DY+DLYLIH+P + K + + Sbjct: 70 EDGTVKREDIFYTSKLWSTSHRPELVRPSLENSLRKLNLDYVDLYLIHFPVSLKPGNELL 129 Query: 487 PTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVK 648 P D G + F VD DTW+A+E GL +S+GVSNFN +QL+ IL+ +K Sbjct: 130 PKDEHGNLIFDTVDLCDTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLK 183 Score = 39.9 bits (89), Expect = 0.18 Identities = 16/34 (47%), Positives = 21/34 (61%) Frame = +2 Query: 653 VTNQVECHPYLNXKRLKQFCEDRDIMITXYSPXG 754 V NQVECH YLN +L +C+ DI++ Y G Sbjct: 187 VCNQVECHLYLNQSKLLAYCKMNDIVLVAYGALG 220 >UniRef50_A2QBD7 Cluster: Catalytic activity: an alcohol + NADP(+) <=> an aldehyde + NADPH; n=4; Trichocomaceae|Rep: Catalytic activity: an alcohol + NADP(+) <=> an aldehyde + NADPH - Aspergillus niger Length = 323 Score = 184 bits (447), Expect = 8e-45 Identities = 85/173 (49%), Positives = 120/173 (69%) Frame = +1 Query: 133 TLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQE 312 T++ GAKIP +G GTW++KP EV AV+ A+ GYRHI CA +Y NE EVG I+ + Sbjct: 8 TINTGAKIPAVGFGTWQAKPLEVENAVEVALREGYRHIDCAAIYRNETEVGNGIR----K 63 Query: 313 GVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPT 492 V RE++FIT KLWNT H P+ V AL+ +L++L + YLDLYL+HWP A+K D FP Sbjct: 64 SGVPREEIFITGKLWNTKHAPEDVEPALDKTLQDLGVAYLDLYLMHWPCAFKGGDKWFPL 123 Query: 493 DADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKP 651 + DG +++DY+ T++A+E L+ G VR++GVSNFN ++L+ +L SV P Sbjct: 124 NDDGVFDLANIDYITTYRAMEKLLATGKVRAIGVSNFNIRRLEELLGQVSVVP 176 Score = 43.2 bits (97), Expect = 0.019 Identities = 17/32 (53%), Positives = 21/32 (65%) Frame = +2 Query: 659 NQVECHPYLNXKRLKQFCEDRDIMITXYSPXG 754 NQ+E HPYL L QFC+ + I+I YSP G Sbjct: 179 NQIEAHPYLQQPDLLQFCQSKGILIEAYSPLG 210 >UniRef50_UPI000065D0BD Cluster: Homolog of Homo sapiens "AKR1B1 protein.; n=1; Takifugu rubripes|Rep: Homolog of Homo sapiens "AKR1B1 protein. - Takifugu rubripes Length = 330 Score = 183 bits (446), Expect = 1e-44 Identities = 107/272 (39%), Positives = 146/272 (53%), Gaps = 27/272 (9%) Frame = +1 Query: 121 VPVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKT 300 +P TL+ GA +PV+G+GTWKS G T+AVK AI GYRHI A+VY NE EVG ++ Sbjct: 2 IPSVTLNTGALMPVLGLGTWKSGKGVTTEAVKVAIGAGYRHIDTAYVYENETEVGAGVQA 61 Query: 301 KIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKE--- 471 I +GVVKRE+LFI SKLW TFH P LVRGA E +L +LN+DY+DLYL+H+P Sbjct: 62 MIDQGVVKREELFIVSKLWCTFHTPSLVRGACEKTLSSLNLDYVDLYLMHFPMGALSATL 121 Query: 472 -----DDAI----------------FPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSL 588 D I FP D ++ ++DTW+A+E LV GL +++ Sbjct: 122 DLTSLTDVIPTVFRDFSPLQPGEDPFPLDEHNQLICDGTSFLDTWEAMEELVDDGLAKAI 181 Query: 589 GVSNFNSKQLQRILDNASVKPGH*PGRMPSVFKPXAIEAVL---RRP*YYDNGVLPRWGX 759 G+SNFN Q++ +L+ +K H P P + L R G Sbjct: 182 GISNFNKDQIEAVLNKPGLK--HKPATNQIECHPHLNQEKLIHFCRSRGISVTAFACLGS 239 Query: 760 PDRPWAKPGDPHLMEDPKLKEIADRLGKXAAQ 855 DR WA +P ++DP++ IA + AQ Sbjct: 240 ADRSWASADEPSFLDDPQINAIARKNQMTPAQ 271 Score = 43.6 bits (98), Expect = 0.015 Identities = 16/33 (48%), Positives = 23/33 (69%) Frame = +2 Query: 656 TNQVECHPYLNXKRLKQFCEDRDIMITXYSPXG 754 TNQ+ECHP+LN ++L FC R I +T ++ G Sbjct: 206 TNQIECHPHLNQEKLIHFCRSRGISVTAFACLG 238 >UniRef50_A7SIT3 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 323 Score = 183 bits (445), Expect = 1e-44 Identities = 98/234 (41%), Positives = 141/234 (60%), Gaps = 3/234 (1%) Frame = +1 Query: 136 LSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQEG 315 L+ GA IP + +GTW+S EV AV+ AI++GYRHI CA +YGNE E+GEA+ + EG Sbjct: 10 LNTGASIPAMALGTWQSSKEEVGNAVRLAIELGYRHIDCAEIYGNEGEIGEALSEVLTEG 69 Query: 316 VVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTD 495 VKRE+LF+TSKLW H PD V A + +L+NL +DYLDLYLIH P A+K+ + + Sbjct: 70 KVKREELFVTSKLWCDSHHPDDVLPACQATLKNLQLDYLDLYLIHIPVAFKKGVRLPHSI 129 Query: 496 ADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPGH*PGRMP 675 A+G I ++ +TW+A+E LV GL +++GVSNF+ K+L ++L+ AS+ P + Sbjct: 130 AEGIIGYTPEGVQNTWQAMEGLVAKGLCKAIGVSNFSVKRLNKLLETASIVPACNQVELH 189 Query: 676 SVFKPXAIEAVLRRP*YYDNGVLPRWGXPDRPWAK---PGDPHLMEDPKLKEIA 828 ++ P G P R K +P +ME+P +KEIA Sbjct: 190 PYLPQEKLKEFCDSKGILLTAYSP-LGNPGRLVPKERLEREPKVMEEPVIKEIA 242 Score = 48.0 bits (109), Expect = 7e-04 Identities = 18/32 (56%), Positives = 25/32 (78%) Frame = +2 Query: 659 NQVECHPYLNXKRLKQFCEDRDIMITXYSPXG 754 NQVE HPYL ++LK+FC+ + I++T YSP G Sbjct: 184 NQVELHPYLPQEKLKEFCDSKGILLTAYSPLG 215 >UniRef50_Q10494 Cluster: Probable oxidoreductase C26F1.07; n=2; Schizosaccharomyces pombe|Rep: Probable oxidoreductase C26F1.07 - Schizosaccharomyces pombe (Fission yeast) Length = 321 Score = 182 bits (443), Expect = 2e-44 Identities = 86/173 (49%), Positives = 117/173 (67%) Frame = +1 Query: 133 TLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQE 312 TL++G+KIP +G+GTW+S+P + AVK A+ GYRHI A +YGNE EVG+ IK E Sbjct: 17 TLADGSKIPGLGLGTWRSEPNQTKNAVKTALQYGYRHIDAAAIYGNEDEVGDGIK----E 72 Query: 313 GVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPT 492 V R+D+++TSKLW H P+ V ALE +L++L +DYLD YLIHWP ++K + FP Sbjct: 73 SGVPRKDIWVTSKLWCNAHAPEAVPKALEKTLKDLKLDYLDEYLIHWPVSFKTGEDKFPK 132 Query: 493 DADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKP 651 D DG + + +TWKA+E L+ G VR +G+SNFN L+RIL A VKP Sbjct: 133 DKDGNLIYEKNPIEETWKAMEKLLETGKVRHIGLSNFNDTNLERILKVAKVKP 185 >UniRef50_P51857 Cluster: 3-oxo-5-beta-steroid 4-dehydrogenase (EC 1.3.1.3) (Delta(4)-3- ketosteroid 5-beta-reductase); n=124; cellular organisms|Rep: 3-oxo-5-beta-steroid 4-dehydrogenase (EC 1.3.1.3) (Delta(4)-3- ketosteroid 5-beta-reductase) - Homo sapiens (Human) Length = 326 Score = 182 bits (442), Expect = 3e-44 Identities = 107/248 (43%), Positives = 143/248 (57%), Gaps = 8/248 (3%) Frame = +1 Query: 136 LSNGAKIPVIGIGTW---KSKP-GEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTK 303 LS+G IP+IG+GT+ KS P G +VK AID GYRHI A++Y NE EVGEAI+ K Sbjct: 12 LSDGNSIPIIGLGTYSEPKSTPKGACATSVKVAIDTGYRHIDGAYIYQNEHEVGEAIREK 71 Query: 304 IQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAI 483 I EG V+RED+F KLW T H P++VR LE +LR L +DY+DLY+I P A+K D I Sbjct: 72 IAEGKVRREDIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLYIIEVPMAFKPGDEI 131 Query: 484 FPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPGH*P 663 +P D +GK + + TW+A+E GLV+SLGVSNFN +QL+ IL+ +K H P Sbjct: 132 YPRDENGKWLYHKSNLCATWEAMEACKDAGLVKSLGVSNFNRRQLELILNKPGLK--HKP 189 Query: 664 GRMPSVFKPXAIEAVLRRP*YYDNGVLPRW---GXPDRP-WAKPGDPHLMEDPKLKEIAD 831 P + L + + V+ + G P W P L++D L + Sbjct: 190 VSNQVECHPYFTQPKLLKFCQQHDIVITAYSPLGTSRNPIWVNVSSPPLLKDALLNSLGK 249 Query: 832 RLGKXAAQ 855 R K AAQ Sbjct: 250 RYNKTAAQ 257 >UniRef50_Q7JVH6 Cluster: LD24696p; n=2; Sophophora|Rep: LD24696p - Drosophila melanogaster (Fruit fly) Length = 311 Score = 181 bits (441), Expect = 4e-44 Identities = 84/181 (46%), Positives = 123/181 (67%), Gaps = 1/181 (0%) Frame = +1 Query: 112 MTSV-PVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGE 288 MT++ P L+NG ++P +G+GTWKS + + + A+D+GYRH+ AFVY NE EVG+ Sbjct: 1 MTNLAPTIRLNNGREMPTLGLGTWKSFESDAYHSTRHALDVGYRHLDTAFVYENEAEVGQ 60 Query: 289 AIKTKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYK 468 AI KI EGVV RE++F+T+KL H P LV A +SL NL ++Y+DLYL+H P K Sbjct: 61 AISEKIAEGVVTREEVFVTTKLGGIHHDPALVERACRLSLSNLGLEYVDLYLMHMPVGQK 120 Query: 469 EDDAIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVK 648 + ++ G ++ +DVDY+DTW+ +E LV GL RS+G+SNFN+ Q +R+L N ++ Sbjct: 121 FHN---DSNVHGTLELTDVDYLDTWREMEKLVDLGLTRSIGLSNFNAAQTERVLANCRIR 177 Query: 649 P 651 P Sbjct: 178 P 178 >UniRef50_UPI0000E4A7CE Cluster: PREDICTED: similar to LOC553452 protein; n=6; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to LOC553452 protein - Strongylocentrotus purpuratus Length = 321 Score = 180 bits (437), Expect = 1e-43 Identities = 104/244 (42%), Positives = 136/244 (55%), Gaps = 4/244 (1%) Frame = +1 Query: 136 LSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQEG 315 L G K+P++G GTW+ KP EV + ++ AID GYRHI A +YGNEK VG+ IK KI +G Sbjct: 10 LPGGRKLPLLGFGTWQIKPEEVGRVIETAIDCGYRHIDEASLYGNEKGVGDGIKAKIDDG 69 Query: 316 VVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTD 495 +KREDLF+TSKLW T P V + SL +L + YLDL+LIH P + FP D Sbjct: 70 TIKREDLFVTSKLWVTDSHPSRVEPSCRQSLSDLGLAYLDLFLIHCPTSAVGGKGPFPMD 129 Query: 496 ADGKIQFSD-VDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKP-GH*PGR 669 +G D +DYVDTW+ +E LV GLVR++GVSNF Q+QR+LD P + Sbjct: 130 DNGLFIGDDTIDYVDTWRIMESLVDKGLVRAIGVSNFTVAQIQRVLDLPPKYPIANVQVE 189 Query: 670 MPSVFKPXAIEAVLRRP*YYDNGVLPRWGXPDRPWAKPG--DPHLMEDPKLKEIADRLGK 843 + ++ P G P+R K DP LMEDP + IA + G Sbjct: 190 CHPFLAQNELIEFCKKQGITVTAYSP-LGSPERVLQKRATTDPLLMEDPVVCAIAKKKGV 248 Query: 844 XAAQ 855 AQ Sbjct: 249 SPAQ 252 Score = 41.5 bits (93), Expect = 0.060 Identities = 16/31 (51%), Positives = 21/31 (67%) Frame = +2 Query: 662 QVECHPYLNXKRLKQFCEDRDIMITXYSPXG 754 QVECHP+L L +FC+ + I +T YSP G Sbjct: 187 QVECHPFLAQNELIEFCKKQGITVTAYSPLG 217 >UniRef50_Q96JD6-2 Cluster: Isoform 2 of Q96JD6 ; n=4; Catarrhini|Rep: Isoform 2 of Q96JD6 - Homo sapiens (Human) Length = 263 Score = 180 bits (437), Expect = 1e-43 Identities = 87/184 (47%), Positives = 120/184 (65%), Gaps = 19/184 (10%) Frame = +1 Query: 154 IPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQEGVVKRED 333 IP +G+ +WK+ PG+VT+AVK+AID GYRH CA+ Y NE+EVG I+ KI+EG V+RED Sbjct: 4 IPAVGLSSWKASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEGAVRRED 63 Query: 334 LFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKE---------DDAIF 486 LFI +KLW T H+ LV A SL+ L ++YLDLYLIHWP +K + F Sbjct: 64 LFIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPMGFKPPHPEWIMSCSELSF 123 Query: 487 ----------PTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDN 636 P D + SD D++DTW+A+E LV GLV+++GVSNFN +QL+R+L+ Sbjct: 124 CLSHPRVQDLPLDESNMVIPSDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERLLNK 183 Query: 637 ASVK 648 ++ Sbjct: 184 PGLR 187 >UniRef50_Q96JD6 Cluster: Aldo-keto reductase family 1 member C-like protein 2; n=37; Euteleostomi|Rep: Aldo-keto reductase family 1 member C-like protein 2 - Homo sapiens (Human) Length = 320 Score = 180 bits (437), Expect = 1e-43 Identities = 87/184 (47%), Positives = 120/184 (65%), Gaps = 19/184 (10%) Frame = +1 Query: 154 IPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQEGVVKRED 333 IP +G+ +WK+ PG+VT+AVK+AID GYRH CA+ Y NE+EVG I+ KI+EG V+RED Sbjct: 4 IPAVGLSSWKASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEGAVRRED 63 Query: 334 LFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKE---------DDAIF 486 LFI +KLW T H+ LV A SL+ L ++YLDLYLIHWP +K + F Sbjct: 64 LFIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPMGFKPPHPEWIMSCSELSF 123 Query: 487 ----------PTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDN 636 P D + SD D++DTW+A+E LV GLV+++GVSNFN +QL+R+L+ Sbjct: 124 CLSHPRVQDLPLDESNMVIPSDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERLLNK 183 Query: 637 ASVK 648 ++ Sbjct: 184 PGLR 187 Score = 52.4 bits (120), Expect = 3e-05 Identities = 19/34 (55%), Positives = 24/34 (70%) Frame = +2 Query: 653 VTNQVECHPYLNXKRLKQFCEDRDIMITXYSPXG 754 +TNQ+ECHPYL K L FC+ RD+ +T Y P G Sbjct: 191 LTNQIECHPYLTQKNLISFCQSRDVSVTAYRPLG 224 >UniRef50_Q0PGJ6 Cluster: Aldo-keto reductase; n=32; Magnoliophyta|Rep: Aldo-keto reductase - Arabidopsis thaliana (Mouse-ear cress) Length = 315 Score = 179 bits (435), Expect = 2e-43 Identities = 97/240 (40%), Positives = 138/240 (57%) Frame = +1 Query: 136 LSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQEG 315 L+ GAK P +G+GTW++ PG V AV A+ IGYRHI CA +YGNEKE+G +K ++ Sbjct: 10 LNTGAKFPSVGLGTWQASPGLVGDAVAAAVKIGYRHIDCAQIYGNEKEIGAVLKKLFEDR 69 Query: 316 VVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTD 495 VVKREDLFITSKLW T H P V AL +L++L ++Y+DLYLIHWP K+ + Sbjct: 70 VVKREDLFITSKLWCTDHDPQDVPEALNRTLKDLQLEYVDLYLIHWPARIKKGSVGIKPE 129 Query: 496 ADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPGH*PGRMP 675 VD TWKA+E L G R++GVSNF++K+L +L+ A V P Sbjct: 130 -----NLLPVDIPSTWKAMEALYDSGKARAIGVSNFSTKKLADLLELARVPPAVNQVECH 184 Query: 676 SVFKPXAIEAVLRRP*YYDNGVLPRWGXPDRPWAKPGDPHLMEDPKLKEIADRLGKXAAQ 855 ++ ++ + + + P G P W K ++++P L +A++LGK AQ Sbjct: 185 PSWRQTKLQEFCKSKGVHLSAYSP-LGSPGTTWLK---SDVLKNPILNMVAEKLGKSPAQ 240 >UniRef50_P27800 Cluster: Aldehyde reductase 1; n=18; root|Rep: Aldehyde reductase 1 - Sporobolomyces salmonicolor Length = 323 Score = 179 bits (435), Expect = 2e-43 Identities = 107/251 (42%), Positives = 149/251 (59%), Gaps = 6/251 (2%) Frame = +1 Query: 121 VPVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKT 300 V TTL+ GA + ++G GTW++ PGEV Q VK AI+ GYRH+ A VY N+ EVG AIK Sbjct: 2 VGTTTLNTGASLELVGYGTWQAAPGEVGQGVKVAIETGYRHLDLAKVYSNQPEVGAAIK- 60 Query: 301 KIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAY-KEDD 477 E VKREDLFITSKLWN HRP+ V AL+ +L+ L ++YLDLYLIHWP A+ E D Sbjct: 61 ---EAGVKREDLFITSKLWNNSHRPEQVEPALDDTLKELGLEYLDLYLIHWPVAFPPEGD 117 Query: 478 A---IFPTDADGKIQFS-DVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASV 645 +FP D +++ +V VDTWKA+ L+ G V+++GVSNF++K + I++ V Sbjct: 118 ITQNLFPKANDKEVKLDLEVSLVDTWKAMVKLLDTGKVKAIGVSNFDAKMVDAIIEATGV 177 Query: 646 KPG-H*PGRMPSVFKPXAIEAVLRRP*YYDNGVLPRWGXPDRPWAKPGDPHLMEDPKLKE 822 P + R P + +P I A + + P G P L++ P++K Sbjct: 178 TPSVNQIERHPLLLQPELI-AHHKAKNIHITAYSPLGNN------TVGAPLLVQHPEIKR 230 Query: 823 IADRLGKXAAQ 855 IA++ G AQ Sbjct: 231 IAEKNGCTPAQ 241 >UniRef50_Q8VC28 Cluster: Aldo-keto reductase family 1 member C13; n=11; Theria|Rep: Aldo-keto reductase family 1 member C13 - Mus musculus (Mouse) Length = 323 Score = 179 bits (435), Expect = 2e-43 Identities = 85/174 (48%), Positives = 122/174 (70%), Gaps = 3/174 (1%) Frame = +1 Query: 136 LSNGAKIPVIGIGTWKSKPGEVTQAVKDA---IDIGYRHIXCAFVYGNEKEVGEAIKTKI 306 L++G IP +G GT+K K +++++ A +D+GYRH+ A+ Y E+E+G+AI++KI Sbjct: 10 LNDGHLIPALGFGTYKPKEVPKSKSLEAACLALDVGYRHVDTAYAYQVEEEIGQAIQSKI 69 Query: 307 QEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIF 486 + GVVKREDLFIT+KLW T RP+LV+ ALE SL+ L +DY+DLY++H+P K D F Sbjct: 70 KAGVVKREDLFITTKLWCTCFRPELVKPALEKSLKKLQLDYVDLYIMHYPVPMKSGDNDF 129 Query: 487 PTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVK 648 P + GK VD+ DTW+ LE GLV+S+GVSNFN +QL+RIL+ +K Sbjct: 130 PVNEQGKSLLDTVDFCDTWERLEECKDAGLVKSIGVSNFNHRQLERILNKPGLK 183 Score = 44.8 bits (101), Expect = 0.006 Identities = 17/34 (50%), Positives = 23/34 (67%) Frame = +2 Query: 653 VTNQVECHPYLNXKRLKQFCEDRDIMITXYSPXG 754 V NQVECH YLN ++L +CE +DI++ Y G Sbjct: 187 VCNQVECHLYLNQRKLLDYCESKDIVLVAYGALG 220 >UniRef50_Q54B70 Cluster: Aldehyde reductase; n=2; Dictyostelium discoideum|Rep: Aldehyde reductase - Dictyostelium discoideum AX4 Length = 297 Score = 178 bits (433), Expect = 4e-43 Identities = 92/177 (51%), Positives = 118/177 (66%), Gaps = 1/177 (0%) Frame = +1 Query: 124 PVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTK 303 P LS+G KIP++G GTWK++ V +AV+ A+D GYRHI CA VY NEKEVGEA K Sbjct: 3 PSFKLSSGHKIPLVGFGTWKAETTLVGKAVEVALDAGYRHIDCAAVYLNEKEVGEAFTKK 62 Query: 304 IQ-EGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDA 480 E VKRED+FITSKLWNTFH+ + VR ALE +L +L + YLDLYL+HWP A++ Sbjct: 63 FTTEATVKREDVFITSKLWNTFHKKEHVRPALERTLSDLGLQYLDLYLVHWPVAFEYTSN 122 Query: 481 IFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKP 651 T G Q V +TW+ +E LV GLV+S+G+SNFN + L +L A +KP Sbjct: 123 DIQT--SGSTQ-EFVSIRETWEEMEKLVDAGLVKSIGLSNFNVQGLMEVLSYARIKP 176 Score = 43.6 bits (98), Expect = 0.015 Identities = 17/32 (53%), Positives = 23/32 (71%) Frame = +2 Query: 659 NQVECHPYLNXKRLKQFCEDRDIMITXYSPXG 754 NQVE HP+L+ LK+FC+ +I +T YSP G Sbjct: 179 NQVELHPFLSQPELKKFCDKHNIHLTAYSPLG 210 >UniRef50_UPI0000E45E29 Cluster: PREDICTED: similar to aldose reductase; n=1; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to aldose reductase - Strongylocentrotus purpuratus Length = 274 Score = 177 bits (430), Expect = 9e-43 Identities = 95/226 (42%), Positives = 127/226 (56%) Frame = +1 Query: 178 WKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQEGVVKREDLFITSKLW 357 W SKPG+V AVK AID GYRHI CA VYGNE EVG +K K VVKRED+FITSKLW Sbjct: 5 WMSKPGQVEAAVKAAIDCGYRHIDCAHVYGNEAEVGAGLKEKFDANVVKREDIFITSKLW 64 Query: 358 NTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTDADGKIQFSDVDYVD 537 N H PD V A +++L+NL + Y+DLYL+HWP AY Sbjct: 65 NNKHHPDDVEQACDITLKNLQLSYVDLYLMHWPMAY------------------------ 100 Query: 538 TWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPGH*PGRMPSVFKPXAIEAVLRR 717 +A+E LV G +++G+SNF+ K ++R+++ A+++P + + + + + Sbjct: 101 --QAMEKLVTSGKCKAIGLSNFSMKMMKRVIEKATIQPANLQVELHPLLTQEKLIEFCKE 158 Query: 718 P*YYDNGVLPRWGXPDRPWAKPGDPHLMEDPKLKEIADRLGKXAAQ 855 P G PDRPW K DP LMEDP + IA + GK AQ Sbjct: 159 HNMTVTAYSP-LGAPDRPWVKDDDPKLMEDPIVTGIATKKGKSPAQ 203 >UniRef50_Q5BKE9 Cluster: LOC594893 protein; n=5; Xenopus tropicalis|Rep: LOC594893 protein - Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) Length = 345 Score = 175 bits (425), Expect = 4e-42 Identities = 98/232 (42%), Positives = 133/232 (57%), Gaps = 4/232 (1%) Frame = +1 Query: 172 GTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQEGVVKREDLFITSK 351 GT KS +V A K A+D+GYRH+ AF+Y +E VG+A + K +G +KREDLF TSK Sbjct: 47 GTEKSFIDDVRVATKMALDLGYRHVDGAFLYSSETGVGQAFREKFADGTLKREDLFYTSK 106 Query: 352 LWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTDADGKIQFSDVDY 531 LWNTFH+P LVR ALE +L L +DY+DLYLIH P ++K + +FP + DG F D Sbjct: 107 LWNTFHQPHLVRPALEKTLSFLQMDYVDLYLIHMPMSFKPAEELFPKNEDGTCAFDQPDL 166 Query: 532 VDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPGH*PGRMPSVFKPXAIEAVL 711 + TW+ALE GLV+S+GVSNFN +QL+ IL+ +K + P P + + Sbjct: 167 LQTWQALEECRDAGLVKSIGVSNFNRRQLEMILNKPGLK--YKPVCNQIECHPYLNQKQM 224 Query: 712 RRP*YYDNGVLPRWGXPDRP----WAKPGDPHLMEDPKLKEIADRLGKXAAQ 855 + V+ +G P W P L+EDP L I + K AQ Sbjct: 225 LEFCKSKDIVVVAYGVLGSPGAGKWVDQSCPILLEDPVLISIGQKYSKSPAQ 276 Score = 48.8 bits (111), Expect = 4e-04 Identities = 17/34 (50%), Positives = 25/34 (73%) Frame = +2 Query: 653 VTNQVECHPYLNXKRLKQFCEDRDIMITXYSPXG 754 V NQ+ECHPYLN K++ +FC+ +DI++ Y G Sbjct: 209 VCNQIECHPYLNQKQMLEFCKSKDIVVVAYGVLG 242 >UniRef50_Q96UH3 Cluster: Aldehyde reductase; n=13; Pezizomycotina|Rep: Aldehyde reductase - Coccidioides posadasii Length = 314 Score = 174 bits (424), Expect = 5e-42 Identities = 81/172 (47%), Positives = 115/172 (66%) Frame = +1 Query: 136 LSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQEG 315 L+ G IP IG GTW+ + + AV A+ GYRHI A VYG EK +G A+ Sbjct: 10 LNTGEDIPAIGFGTWQDENAQ-EDAVLTALSAGYRHIDTAAVYGTEKAIGRALA----RS 64 Query: 316 VVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTD 495 + R++LFITSKLWN HRP+ V A++ SL+NL IDYLDLYL+HWP A+ D +FP D Sbjct: 65 RLSRDELFITSKLWNNKHRPEDVEQAIDQSLKNLEIDYLDLYLMHWPAAFAPGDDMFPKD 124 Query: 496 ADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKP 651 + G + D+DYVDT+KA+E LV G +++G+SNF+ +++R+L++ S+ P Sbjct: 125 SQGNSKTVDIDYVDTYKAMEKLVKSGKTKAIGISNFSKGEMERLLESCSIVP 176 >UniRef50_A4RQH8 Cluster: Predicted protein; n=2; Ostreococcus|Rep: Predicted protein - Ostreococcus lucimarinus CCE9901 Length = 337 Score = 172 bits (419), Expect = 2e-41 Identities = 83/170 (48%), Positives = 107/170 (62%) Frame = +1 Query: 139 SNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQEGV 318 +NG +IP +G+GTWK++P EV AV+DA+ GY H+ CA Y NE EVGEA++ + G Sbjct: 11 ANGLRIPRVGLGTWKARPNEVRDAVRDALGAGYAHVDCAAAYANESEVGEALREAFERGD 70 Query: 319 VKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTDA 498 KRED+F+TSKLWN RP VR AL +L +L + YLDLYLIHWP A+K + P DA Sbjct: 71 AKREDVFVTSKLWNDRRRPRDVREALMTTLNDLGVGYLDLYLIHWPVAWKRGTVLQP-DA 129 Query: 499 DGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVK 648 + I + W LE V GLVR +GVSNFN QL + D+ K Sbjct: 130 EASI-------AECWSELERCVADGLVRHIGVSNFNEAQLAALCDDPRTK 172 >UniRef50_Q2V420 Cluster: Uncharacterized protein At2g37770.1; n=1; Arabidopsis thaliana|Rep: Uncharacterized protein At2g37770.1 - Arabidopsis thaliana (Mouse-ear cress) Length = 283 Score = 171 bits (415), Expect = 6e-41 Identities = 84/172 (48%), Positives = 111/172 (64%) Frame = +1 Query: 136 LSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQEG 315 L+ GAK P +G+GTW++ PG V AV A+ IGYRHI CA +YGNEKE+G +K ++ Sbjct: 10 LNTGAKFPSVGLGTWQASPGLVGDAVAAAVKIGYRHIDCAQIYGNEKEIGAVLKKLFEDR 69 Query: 316 VVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTD 495 VVKREDLFITSKLW T H P V AL +L++L ++Y+DLYLIHWP K+ + Sbjct: 70 VVKREDLFITSKLWCTDHDPQDVPEALNRTLKDLQLEYVDLYLIHWPARIKKGSVGIKPE 129 Query: 496 ADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKP 651 VD TWKA+E L G R++GVSNF++K+L +L+ A V P Sbjct: 130 -----NLLPVDIPSTWKAMEALYDSGKARAIGVSNFSTKKLADLLELARVPP 176 >UniRef50_UPI0000498F1F Cluster: oxidoreductase, aldo/keto reductase family; n=2; Entamoeba histolytica HM-1:IMSS|Rep: oxidoreductase, aldo/keto reductase family - Entamoeba histolytica HM-1:IMSS Length = 305 Score = 168 bits (409), Expect = 3e-40 Identities = 97/241 (40%), Positives = 136/241 (56%) Frame = +1 Query: 133 TLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQE 312 TL+NG KIP +G+GTW S GEV +AV+ AI GYRHI CA YGNEKEVG+ IK+ I + Sbjct: 6 TLNNGYKIPKLGLGTWMSANGEVGKAVEIAIKNGYRHIDCAKAYGNEKEVGDGIKSAIAK 65 Query: 313 GVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPT 492 G VKRE+LF+T+KLW+T + VR A SL+ L ++YLDLY+IH P + F Sbjct: 66 GYVKREELFVTTKLWSTDKHKEDVRPACLESLKKLQLEYLDLYIIHIPLTADKKTGEFTE 125 Query: 493 DADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPGH*PGRM 672 + + +TW+ +E LV GLV+S+GVSNFN K+L+ +L A ++P Sbjct: 126 EI--------IPIEETWREMEKLVEEGLVKSIGVSNFNIKKLEELLAIAKIQPAVNQFEF 177 Query: 673 PSVFKPXAIEAVLRRP*YYDNGVLPRWGXPDRPWAKPGDPHLMEDPKLKEIADRLGKXAA 852 ++ + ++ + G P P G P E+ +K IA + K AA Sbjct: 178 HIYYQRPKLHQFCKKHNIHITGYCPL----GNPGISSGVPAPFENEVVKAIAKKHNKKAA 233 Query: 853 Q 855 Q Sbjct: 234 Q 234 >UniRef50_Q0IBY6 Cluster: Alcohol dehydrogenase; n=2; Chroococcales|Rep: Alcohol dehydrogenase - Synechococcus sp. (strain CC9311) Length = 336 Score = 167 bits (406), Expect = 7e-40 Identities = 95/252 (37%), Positives = 147/252 (58%), Gaps = 3/252 (1%) Frame = +1 Query: 109 IMTSVPVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGE 288 ++ ++ +LSNG ++P++G+GT KS+ +V ++V++AI IGYRHI CA +YGNE+EVG+ Sbjct: 15 VIPTMQYASLSNGDRMPLLGLGTGKSESRQVYKSVREAIKIGYRHIDCASIYGNEEEVGD 74 Query: 289 AIKTKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYK 468 AI+ IQ + R +L+ITSKLW+ H + V AL SL+NL +DYL+LYLIHWP + Sbjct: 75 AIRDAIQNHEITRSELWITSKLWSNCHGKNHVEAALSQSLQNLGVDYLNLYLIHWPVGIR 134 Query: 469 EDDAIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVK 648 + F D + + +TW+A+E GL + +GVSNF K+LQ+++ + K Sbjct: 135 PEKT-FAESVDDLLTPEESPISETWEAMESTRDKGLTKHIGVSNFTVKKLQQLVSHCKQK 193 Query: 649 PG-H*PGRMPSVFKPXAIEAVLRRP*YYDNGVLPRWGXPDRPWA-KPGD-PHLMEDPKLK 819 P + P + +P IE P G DRP + K D P +++ P ++ Sbjct: 194 PEVNQVEHHPLLQQPTLIEYCASEE-ILITAYSP-LGSMDRPQSLKVKDAPAVLDHPVIR 251 Query: 820 EIADRLGKXAAQ 855 IA+ G AQ Sbjct: 252 AIAETRGCSPAQ 263 >UniRef50_UPI0000D9A956 Cluster: PREDICTED: similar to aldo-keto reductase family 1, member B10, partial; n=1; Macaca mulatta|Rep: PREDICTED: similar to aldo-keto reductase family 1, member B10, partial - Macaca mulatta Length = 275 Score = 167 bits (405), Expect = 9e-40 Identities = 104/234 (44%), Positives = 134/234 (57%), Gaps = 9/234 (3%) Frame = +1 Query: 181 KSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQEGVVKREDLFITSK--- 351 KS G+V +AVK AID GYRHI CA+VY NE EVGEAI+ KIQE VKREDLFI SK Sbjct: 42 KSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEKIQEQAVKREDLFIVSKVHM 101 Query: 352 ---LWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTDADGKIQFSD 522 LW TF LVR A E +L++L + YLD+YLIHWPQ +K Sbjct: 102 AHWLWTTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFK------------------ 143 Query: 523 VDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPGH*PGRMPSVFKPXAIE 702 A+E LV GLV++LG+SNFN Q++++L+ +K + P P + Sbjct: 144 --------AMEELVDEGLVKALGISNFNHFQIEKLLNKPGLK--YKPVTNQVECHPYLTQ 193 Query: 703 AVLRRP*YYDNGVLPRW---GXPDRPWAKPGDPHLMEDPKLKEIADRLGKXAAQ 855 L + + + + G PDRPWAKP DP L+E+PK+KEIA + K AQ Sbjct: 194 EKLIQYCHSKGITITAYSPLGSPDRPWAKPEDPSLLEEPKIKEIAAKHKKTTAQ 247 Score = 52.0 bits (119), Expect = 4e-05 Identities = 21/34 (61%), Positives = 25/34 (73%) Frame = +2 Query: 653 VTNQVECHPYLNXKRLKQFCEDRDIMITXYSPXG 754 VTNQVECHPYL ++L Q+C + I IT YSP G Sbjct: 181 VTNQVECHPYLTQEKLIQYCHSKGITITAYSPLG 214 >UniRef50_Q7QVQ9 Cluster: GLP_302_44328_45269; n=1; Giardia lamblia ATCC 50803|Rep: GLP_302_44328_45269 - Giardia lamblia ATCC 50803 Length = 313 Score = 166 bits (403), Expect = 2e-39 Identities = 77/169 (45%), Positives = 111/169 (65%), Gaps = 4/169 (2%) Frame = +1 Query: 157 PVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQEGV--VKRE 330 P +G GTW++ P V AV+ A+ GYRHI CA+VY NE+ +G A ++ +KRE Sbjct: 5 PRLGFGTWQAPPEAVQTAVETALMTGYRHIDCAYVYQNEEAIGRAFGKIFKDASSGIKRE 64 Query: 331 DLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDA--IFPTDADG 504 D++ITSKLWN HRP+LVR + ++ +L +DYLDL+L+HWP A+ +D +FP DA+G Sbjct: 65 DVWITSKLWNYNHRPELVREQCKKTMSDLQVDYLDLFLVHWPLAFVRNDVGDLFPKDAEG 124 Query: 505 KIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKP 651 + V DTW+A+E LV GLV+ +GVSN+ L +L+ A +KP Sbjct: 125 RAMLEKVPLADTWRAMEQLVEEGLVKHIGVSNYTVPLLADLLNYAKIKP 173 Score = 36.7 bits (81), Expect = 1.7 Identities = 16/40 (40%), Positives = 21/40 (52%) Frame = +2 Query: 653 VTNQVECHPYLNXKRLKQFCEDRDIMITXYSPXGXLPTDP 772 + NQ+E HP+ +FC D I +T YSP G DP Sbjct: 174 LVNQIEIHPWHPNDATVKFCLDNGIGVTAYSPMGGSYADP 213 >UniRef50_A3U9Y0 Cluster: Aldehyde reductase; n=5; Bacteroidetes|Rep: Aldehyde reductase - Croceibacter atlanticus HTCC2559 Length = 316 Score = 165 bits (400), Expect = 4e-39 Identities = 91/240 (37%), Positives = 132/240 (55%), Gaps = 4/240 (1%) Frame = +1 Query: 127 VTTLS--NGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKT 300 +TTL +G IP IG+GTWKS P +V +AVK A++ GY+HI CA Y NE VGEA K Sbjct: 1 MTTLKFRDGDSIPSIGLGTWKSDPEDVKKAVKIALENGYKHIDCAAAYDNEDAVGEAFKE 60 Query: 301 KIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDA 480 + G VKRED+F+TSKLWN H+ + V AL+ +L++LN+DYLDLYL+HWP A+K Sbjct: 61 SFESGNVKREDIFVTSKLWNNAHKKEDVIPALKKTLKDLNLDYLDLYLMHWPVAFKPSVN 120 Query: 481 IFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPGH* 660 FP + + + +T A+ GL++ +GVSNF+ ++L+ + P Sbjct: 121 GFPEKDEDYLSLEEAPLHETLNAMIEAKKQGLIKHVGVSNFSKEKLESLKGKVEEMPEMN 180 Query: 661 PGRMPSVFKPXAIEAVLRRP*YYDNGVLPRWGXPDRPWAKPGD--PHLMEDPKLKEIADR 834 + + + + G P G DR D P L ED +K++A+R Sbjct: 181 QVELHPYLPQNDLYSYCSKEGILLTGYSP-LGSGDRSEGMKADDEPSLFEDDTIKKVAER 239 >UniRef50_A2R6Z3 Cluster: Catalytic activity: an alcohol + NADP(+) <=> an aldehyde + NADPH; n=9; Pezizomycotina|Rep: Catalytic activity: an alcohol + NADP(+) <=> an aldehyde + NADPH - Aspergillus niger Length = 345 Score = 164 bits (399), Expect = 5e-39 Identities = 83/174 (47%), Positives = 111/174 (63%), Gaps = 2/174 (1%) Frame = +1 Query: 136 LSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQEG 315 L+ G +P +G+GTW+SK EV AV A+ GYRHI A VYGNE+EVG+ ++ Sbjct: 9 LNTGYDMPAVGLGTWQSKKDEVRDAVIAALKCGYRHIDAAAVYGNEQEVGDGMRLS---- 64 Query: 316 VVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYK-EDDAIFP- 489 V RE++F+TSKLWNT H P+ V A++ SL +L DYLDLYLIHWP A++ I P Sbjct: 65 GVPREEIFLTSKLWNTHHHPENVEEAVDKSLADLQTDYLDLYLIHWPVAFRYSTTTIQPV 124 Query: 490 TDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKP 651 + G I DV DTW A+E LV G VRS+GVSNF ++++ +L A + P Sbjct: 125 NEQTGLIDVVDVPIKDTWAAMEKLVEKGKVRSIGVSNFTREKIEELLKTAKITP 178 >UniRef50_Q22352 Cluster: Putative uncharacterized protein T08H10.1; n=2; Caenorhabditis|Rep: Putative uncharacterized protein T08H10.1 - Caenorhabditis elegans Length = 333 Score = 162 bits (393), Expect = 3e-38 Identities = 95/258 (36%), Positives = 149/258 (57%), Gaps = 8/258 (3%) Frame = +1 Query: 106 LIMTSVPVTTLSNGAKIPVIGIGTWKSKP-GEVTQAVKDAIDIGYRHIXCAFVYGNEKEV 282 + + S+P+ T GA++P+ G+GTW+ K E+T A++ A+D GYR I A +Y NE + Sbjct: 1 MTVDSIPLNT---GAQLPLFGLGTWQVKDEAELTVALRAALDAGYRLIDTAHLYQNEHII 57 Query: 283 GEAIKTKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQA 462 G+ + I G +KRED+F+TSKL T H P+ V +E L+ L ++Y+DLYLIH P Sbjct: 58 GKVLHEYISSGKLKREDIFVTSKLPFTAHAPEDVPKCVESQLKALQLEYIDLYLIHCPFP 117 Query: 463 YKEDDAIF-PTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNA 639 +K + F P +G++ +++ ++DTW+ALE L G +++LGVSNF+ QLQ + D A Sbjct: 118 FKHQEGSFAPLMENGELAVTEIAHIDTWRALEKLYKEGKLKALGVSNFSCNQLQALYDAA 177 Query: 640 SVKPGH*PGRMPSVFKPXAIEAVLRRP*YYDNGVLPRWGXPDRPWAKP------GDPHLM 801 VKP + + + A+ ++ P G P R A+P GDP L Sbjct: 178 EVKPANQQVECHIYWPQQELRALCKKLGVTVTAYAP-LGSPGRKAARPDGVWPEGDPLL- 235 Query: 802 EDPKLKEIADRLGKXAAQ 855 +P +K++A + K AAQ Sbjct: 236 -EPIVKQLAAKYHKTAAQ 252 >UniRef50_Q2UGR1 Cluster: Aldo/keto reductase family proteins; n=2; Ascomycota|Rep: Aldo/keto reductase family proteins - Aspergillus oryzae Length = 323 Score = 160 bits (389), Expect = 8e-38 Identities = 92/241 (38%), Positives = 129/241 (53%), Gaps = 2/241 (0%) Frame = +1 Query: 136 LSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQEG 315 L++G IP IG+GTW SKP EV AV+ A+ GYRHI A Y NE EVG K + Sbjct: 9 LNSGYNIPAIGLGTWLSKPHEVENAVEAALRAGYRHIDAAACYQNENEVGNGWK----KS 64 Query: 316 VVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKE-DDAIFPT 492 V R+ +FITSKLWNT H P+ V A+ +L++L DYLDLYLIHWP A++ ++ + P Sbjct: 65 GVPRDQIFITSKLWNTHHHPEHVEEAVNKTLKDLQTDYLDLYLIHWPVAFEHTNETLTPI 124 Query: 493 D-ADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPGH*PGR 669 D + + ++V DTW ALE LV +RS+G+SNF ++ +L A + P Sbjct: 125 DPVTKRFRLANVPIADTWAALEKLVEAKKIRSIGISNFTQDKIDDLLKTAKIPPAVNQIE 184 Query: 670 MPSVFKPXAIEAVLRRP*YYDNGVLPRWGXPDRPWAKPGDPHLMEDPKLKEIADRLGKXA 849 + + L+ P P +++DP +K IAD+LGK Sbjct: 185 AHPYLQQPGLHKYLKEKNILSVAYSPLGNNIYNA------PRVVDDPDVKAIADKLGKDP 238 Query: 850 A 852 A Sbjct: 239 A 239 Score = 35.9 bits (79), Expect = 3.0 Identities = 13/32 (40%), Positives = 21/32 (65%) Frame = +2 Query: 659 NQVECHPYLNXKRLKQFCEDRDIMITXYSPXG 754 NQ+E HPYL L ++ ++++I+ YSP G Sbjct: 181 NQIEAHPYLQQPGLHKYLKEKNILSVAYSPLG 212 >UniRef50_A2EYY6 Cluster: Oxidoreductase, aldo/keto reductase family protein; n=9; Trichomonas vaginalis G3|Rep: Oxidoreductase, aldo/keto reductase family protein - Trichomonas vaginalis G3 Length = 308 Score = 159 bits (386), Expect = 2e-37 Identities = 95/245 (38%), Positives = 138/245 (56%), Gaps = 10/245 (4%) Frame = +1 Query: 151 KIPVIGIGTWKSKPGE-----VTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQEG 315 +IP IG+GTWKS E +T A+K+A GY HI CA Y NE VG+A++ G Sbjct: 3 RIPTIGLGTWKSPRSEDLVNAITYAIKEA---GYVHIDCALCYENEDIVGQALQQCWDSG 59 Query: 316 VVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKE---DDAIF 486 + KRE+++ITSKLWNT HR ++V A +L++L +DYLDLYL+H+P A++ ++ Sbjct: 60 I-KRENIWITSKLWNTHHRLEIVEEACRKTLKDLRLDYLDLYLMHYPFAFQNTGIGGSLN 118 Query: 487 PTDADGKIQFSD-VDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRI-LDNASVKPGH* 660 P D G F D V +DTWKA+E LV GLV+ +GVSN+ QL+R+ +A P Sbjct: 119 PLDEKGNTIFDDGVSLIDTWKAMEKLVEKGLVKRIGVSNWTINQLERLKYSDAKTTPYTN 178 Query: 661 PGRMPSVFKPXAIEAVLRRP*YYDNGVLPRWGXPDRPWAKPGDPHLMEDPKLKEIADRLG 840 + + + + G G PD WAKP +P +++D +L +IA G Sbjct: 179 QVEFNLYMQQGPLREYMHKEGIIVTG-YSTLGTPD--WAKPDEPVVLKDEELNKIAAETG 235 Query: 841 KXAAQ 855 K + Sbjct: 236 KSVGE 240 >UniRef50_P38715 Cluster: NADPH-dependent aldose reductase GRE3; n=39; cellular organisms|Rep: NADPH-dependent aldose reductase GRE3 - Saccharomyces cerevisiae (Baker's yeast) Length = 327 Score = 159 bits (386), Expect = 2e-37 Identities = 82/185 (44%), Positives = 115/185 (62%), Gaps = 10/185 (5%) Frame = +1 Query: 127 VTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKI 306 + TL+NG K+P++G+G WK + +AI +GYR A YGNEKEVGE I+ I Sbjct: 4 LVTLNNGLKMPLVGLGCWKIDKKVCANQIYEAIKLGYRLFDGACDYGNEKEVGEGIRKAI 63 Query: 307 QEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYK------ 468 EG+V R+D+F+ SKLWN FH PD V+ AL+ +L ++ +DYLDLY IH+P A+K Sbjct: 64 SEGLVSRKDIFVVSKLWNNFHHPDHVKLALKKTLSDMGLDYLDLYYIHFPIAFKYVPFEE 123 Query: 469 EDDAIFPTDAD----GKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDN 636 + F T AD G I + V +DT++ALE V GL++S+GVSNF +Q +L Sbjct: 124 KYPPGFYTGADDEKKGHITEAHVPIIDTYRALEECVDEGLIKSIGVSNFQGSLIQDLLRG 183 Query: 637 ASVKP 651 +KP Sbjct: 184 CRIKP 188 Score = 36.3 bits (80), Expect = 2.2 Identities = 15/34 (44%), Positives = 20/34 (58%) Frame = +2 Query: 653 VTNQVECHPYLNXKRLKQFCEDRDIMITXYSPXG 754 V Q+E HPYL + L +FC+ DI + YS G Sbjct: 189 VALQIEHHPYLTQEHLVEFCKLHDIQVVAYSSFG 222 >UniRef50_Q1IN88 Cluster: Aldehyde reductase; n=5; Bacteria|Rep: Aldehyde reductase - Acidobacteria bacterium (strain Ellin345) Length = 313 Score = 159 bits (385), Expect = 2e-37 Identities = 92/242 (38%), Positives = 134/242 (55%), Gaps = 2/242 (0%) Frame = +1 Query: 136 LSNGA-KIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQE 312 L +GA IP +G GT + P A +DA+ G+RH CA Y NE+EVGEA++ Sbjct: 13 LHHGAGHIPALGFGTLIADPALTITATRDALAAGFRHFDCAERYRNEREVGEALRAGRAA 72 Query: 313 GVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPT 492 G + RE++F+T+KLWNT HRP+ V A E SL L +DYLDLYLIH P A++ D P Sbjct: 73 GNIAREEIFVTTKLWNTNHRPERVEPAFEASLDRLGLDYLDLYLIHTPFAFQPGDEQDPR 132 Query: 493 DADGKIQFSD-VDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPGH*PGR 669 D +G + + + V +TW ALE LV G R++G+S+ + +L I + A +KP Sbjct: 133 DQNGSVIYDEGVTLRETWSALENLVDRGRCRAIGLSDISMDRLAPIYEAARIKPAVVQVE 192 Query: 670 MPSVFKPXAIEAVLRRP*YYDNGVLPRWGXPDRPWAKPGDPHLMEDPKLKEIADRLGKXA 849 + +R NG++ P +PG L+EDP + +++R+GK A Sbjct: 193 SHPYLPETELLEFCKR-----NGIVLLAFAPLGHGMRPG---LLEDPVITSVSERVGKTA 244 Query: 850 AQ 855 AQ Sbjct: 245 AQ 246 >UniRef50_Q9U2J5 Cluster: Putative uncharacterized protein; n=2; Caenorhabditis|Rep: Putative uncharacterized protein - Caenorhabditis elegans Length = 339 Score = 158 bits (383), Expect = 4e-37 Identities = 84/253 (33%), Positives = 133/253 (52%), Gaps = 5/253 (1%) Frame = +1 Query: 112 MTSVPVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEA 291 M TL++G ++PVIG GTW+ + V+DA++ GYRHI A + N++EV Sbjct: 1 MPIADTVTLNSGYEMPVIGYGTWQLPKNLAAERVRDALEAGYRHIDSALSFKNQEEVAAG 60 Query: 292 IKTKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKE 471 IK + V+RE+LF++SK+WNT+H + ++ L Y+DL +IHWP + E Sbjct: 61 IKDWCKIRKVRREELFLSSKIWNTYHSRNRCMQQIDEMLEIFETTYMDLIVIHWPFGWAE 120 Query: 472 DD-----AIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDN 636 D+ ++P A+GK+++SDVDY++TWKALE G +RS+G++NFN Q++++ Sbjct: 121 DEPPGERGLWPRGANGKMRYSDVDYLETWKALEDAHRSGKIRSIGLANFNIGQVEQVWTK 180 Query: 637 ASVKPGH*PGRMPSVFKPXAIEAVLRRP*YYDNGVLPRWGXPDRPWAKPGDPHLMEDPKL 816 +KP M I R + + K DP+L+ + L Sbjct: 181 GLIKPAVLQVEMNPFLDQEEIRQFCREKGIILTAFMLTGNPGSALYRKHEDPNLLYNETL 240 Query: 817 KEIADRLGKXAAQ 855 + IA GK Q Sbjct: 241 QSIAKGHGKSVVQ 253 >UniRef50_A2FPE2 Cluster: Oxidoreductase, aldo/keto reductase family protein; n=3; Trichomonas vaginalis G3|Rep: Oxidoreductase, aldo/keto reductase family protein - Trichomonas vaginalis G3 Length = 309 Score = 158 bits (383), Expect = 4e-37 Identities = 91/241 (37%), Positives = 142/241 (58%), Gaps = 7/241 (2%) Frame = +1 Query: 154 IPVIGIGTWKSK-PGEVTQAVKDAI-DIGYRHIXCAFVYGNEKEVGEAIKTKIQEGVVKR 327 IP IG+GT+ ++ P + AV AI D GYRH+ CA Y N++ +GEA+ +G VKR Sbjct: 4 IPSIGLGTFLAEDPAALKAAVHSAIEDSGYRHVDCAAYYKNQEIIGEALSEIFAKGQVKR 63 Query: 328 EDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAY--KEDDAIFPTDAD 501 E+++ITSK+WNT HRPDL+ ++ +L+ L ++YLDL L+HW A+ +EDD P D Sbjct: 64 EEVWITSKVWNTKHRPDLLVKDVKKTLKELKLEYLDLVLVHWACAFQSREDDEYLPRDET 123 Query: 502 GKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPGH*PGRMPS- 678 GKI ++D ++TWKA+E GL + +GVSNF+ +QL+R+ + VK ++ S Sbjct: 124 GKIITENIDILETWKAMEECYNLGLAKHIGVSNFSIEQLERMRYDPGVKIQPYCNQVESH 183 Query: 679 --VFKPXAIEAVLRRP*YYDNGVLPRWGXPDRPWAKPGDPHLMEDPKLKEIADRLGKXAA 852 + + ++ + +R Y + P+ P L++DP L E+A +GK A Sbjct: 184 MYLQQQPMLDYLTQRKMYMISYTCLGRATLKGPYGYP----LLQDPVLNEVAKEIGKTPA 239 Query: 853 Q 855 Q Sbjct: 240 Q 240 >UniRef50_Q4PAT5 Cluster: Putative uncharacterized protein; n=1; Ustilago maydis|Rep: Putative uncharacterized protein - Ustilago maydis (Smut fungus) Length = 700 Score = 157 bits (382), Expect = 6e-37 Identities = 78/179 (43%), Positives = 115/179 (64%), Gaps = 6/179 (3%) Frame = +1 Query: 133 TLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQE 312 TL+NGA+IP +G GTWK + T AV AI GYRHI CA+ Y NE +A+ I++ Sbjct: 13 TLANGAQIPKLGFGTWKMSKEQATPAVAHAIKTGYRHIDCAWAYRNE----DAVAAGIKK 68 Query: 313 GVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAY-KEDDAIFP 489 V R L++TSKLWN+FH P+ V AL+ SL++L DYLDLYL+HWP A+ ++ P Sbjct: 69 AGVPRSQLWLTSKLWNSFHHPEHVEKALDASLKDLGTDYLDLYLMHWPVAFLNSKGSMVP 128 Query: 490 ---TDADGKIQFSDV--DYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKP 651 + ++ D+ D++ T++ +E +V G VR++GVSNFN ++ ++D AS+KP Sbjct: 129 SIRSTGGHPVESEDLSRDFMATYRVMEEMVKKGKVRNIGVSNFNIRRTSEVVDEASIKP 187 >UniRef50_Q8SSK6 Cluster: ALDOSE REDUCTASE; n=1; Encephalitozoon cuniculi|Rep: ALDOSE REDUCTASE - Encephalitozoon cuniculi Length = 301 Score = 157 bits (380), Expect = 1e-36 Identities = 76/173 (43%), Positives = 103/173 (59%), Gaps = 1/173 (0%) Frame = +1 Query: 136 LSNGAKIPVIGIGTWKSKPGEVTQ-AVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQE 312 L+NG +IP +G+GTW + V + A+++A+ +GYRHI AF+YGNEK +G +K E Sbjct: 8 LNNGKEIPTVGLGTWGMEDEAVLEGAIRNALSLGYRHIDTAFIYGNEKMIGNILKKLFDE 67 Query: 313 GVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPT 492 GVV+R+DLFITSKLWNTFH L SL +L +DY+DLYLIHWP + Sbjct: 68 GVVQRKDLFITSKLWNTFH--GCPEDGLRRSLNDLQMDYVDLYLIHWPVTFDPAPDGTVE 125 Query: 493 DADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKP 651 K D V WK +E LV GL +S+G+SNF ++IL + P Sbjct: 126 SCGKKYNVGKFDAVGVWKKMEALVDLGLAKSIGISNFGKANTEKILGTCRICP 178 Score = 37.9 bits (84), Expect = 0.73 Identities = 15/34 (44%), Positives = 20/34 (58%) Frame = +2 Query: 662 QVECHPYLNXKRLKQFCEDRDIMITXYSPXGXLP 763 Q+E HPYLN K L +F + + I + YS G P Sbjct: 182 QIELHPYLNQKELVEFMKSKGIQVISYSSLGSAP 215 >UniRef50_Q55FL3 Cluster: Aldo-keto reductase; n=2; Dictyostelium discoideum AX4|Rep: Aldo-keto reductase - Dictyostelium discoideum AX4 Length = 321 Score = 156 bits (379), Expect = 1e-36 Identities = 81/178 (45%), Positives = 115/178 (64%), Gaps = 6/178 (3%) Frame = +1 Query: 136 LSNGAKIPVIGIGTWKSK-PGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQE 312 L++G +IP IG+GT+ S+ PGEV A+ +A+ GYRHI A YGNEK +G ++K +E Sbjct: 19 LNDGNQIPSIGLGTYYSENPGEVGDAINNALKNGYRHIDGAAFYGNEKVIGNSLKEIFKE 78 Query: 313 GVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPT 492 G +KRED+F TSKLWN+ H +LV ++ +L I YLDLYLIHWP A++ + + T Sbjct: 79 GEIKREDIFYTSKLWNSCHNSNLVVKHCVKTIEDLGIGYLDLYLIHWPIAFENSNPLGLT 138 Query: 493 -----DADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKP 651 D +G + V +TW+ +E LV GLV+S+GVSNFN + L +L A +KP Sbjct: 139 IEPLRDQNGNPIIAPVSIRETWQEMEKLVELGLVKSIGVSNFNVQNLVDLLTYAKIKP 196 Score = 41.9 bits (94), Expect = 0.045 Identities = 16/34 (47%), Positives = 23/34 (67%) Frame = +2 Query: 653 VTNQVECHPYLNXKRLKQFCEDRDIMITXYSPXG 754 V NQVE HPYL +L+++C+ +I + YSP G Sbjct: 197 VVNQVEIHPYLTQFKLQEYCDKYEIKLVAYSPLG 230 >UniRef50_Q7ZA52 Cluster: Aldose reductase; n=6; Pezizomycotina|Rep: Aldose reductase - Magnaporthe grisea (Rice blast fungus) (Pyricularia grisea) Length = 312 Score = 156 bits (378), Expect = 2e-36 Identities = 80/177 (45%), Positives = 112/177 (63%), Gaps = 4/177 (2%) Frame = +1 Query: 133 TLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQE 312 TL+ GAKIP G+GTW+ G + +AV AI GYR I A+VYGNE+EVG+ I+ I Sbjct: 7 TLNTGAKIPAFGLGTWQGDKGVIKEAVLTAIKSGYRLIDGAYVYGNEEEVGQGIREAISS 66 Query: 313 GVVKREDLFITSKLWNTF-HRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKED--DAI 483 G+VKREDLF+ SK W T+ R +L L+ SL+ L +DY+DLYL+HWP + D Sbjct: 67 GIVKREDLFVVSKCWATYTTRCEL---GLDQSLKLLGLDYVDLYLVHWPILMNPEGNDEK 123 Query: 484 FPTDADGKIQFSDV-DYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKP 651 FP ADG ++VDTWK +E L G +++GVSN++ L+++L +A+ P Sbjct: 124 FPKHADGSRDIIHTHNHVDTWKLMEKLPATGKTKAVGVSNYSKAWLEQLLPHATTVP 180 Score = 36.7 bits (81), Expect = 1.7 Identities = 16/32 (50%), Positives = 20/32 (62%) Frame = +2 Query: 659 NQVECHPYLNXKRLKQFCEDRDIMITXYSPXG 754 NQVE HP L + L FC+++ I I YSP G Sbjct: 183 NQVENHPQLPQQELVDFCKEKGIHIMAYSPLG 214 >UniRef50_A2QVE5 Cluster: Similarity: shows similarity to several dehydrogenases of different specificities; n=4; Pezizomycotina|Rep: Similarity: shows similarity to several dehydrogenases of different specificities - Aspergillus niger Length = 381 Score = 156 bits (378), Expect = 2e-36 Identities = 79/180 (43%), Positives = 111/180 (61%), Gaps = 7/180 (3%) Frame = +1 Query: 133 TLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQE 312 TL++GA+IP +G GTW+S PG+V AV +A+ GYRH+ A +Y N++EV E IK ++ Sbjct: 8 TLNSGAQIPQLGFGTWQSAPGQVGDAVYEALKAGYRHLDLATIYQNQREVAEGIKRAYKD 67 Query: 313 GV-VKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFP 489 +KRED+FITSKLWN+ H P +V AL+ L L +DYLDLYL+HWP ++ +FP Sbjct: 68 VPGLKREDIFITSKLWNSQHDPAVVEKALDECLAELELDYLDLYLVHWPVSFTTGSELFP 127 Query: 490 TDADGKIQFSDV------DYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKP 651 D ++ DV VDTWKA+ L R++GVSN L+ I++ V P Sbjct: 128 LVKDSSVEGGDVVINDDISIVDTWKAMTQLP-KSKARTVGVSNHMIPHLEAIINATGVVP 186 >UniRef50_Q7PLK6 Cluster: CG40064-PA; n=1; Drosophila melanogaster|Rep: CG40064-PA - Drosophila melanogaster (Fruit fly) Length = 361 Score = 155 bits (377), Expect = 2e-36 Identities = 73/154 (47%), Positives = 107/154 (69%), Gaps = 2/154 (1%) Frame = +1 Query: 196 EVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQEGVVKREDLFITSKLWNTFHRP 375 + + AV AI+ G+RH A+ Y NEKE+GEA++T+I+ G + RE++F+T+KLWNT H P Sbjct: 45 QCSAAVHCAIETGFRHFDTAYYYENEKEIGEALRTQIKMGNISRENIFLTTKLWNTHHDP 104 Query: 376 DLVRGALEVSLRNLNIDYLDLYLIHWPQAYKE--DDAIFPTDADGKIQFSDVDYVDTWKA 549 VR E L L Y+DLYL+H+P YK D+ + P D ++Q ++DY+DTW+A Sbjct: 105 RDVRRICEKQLELLGFSYIDLYLMHFPVGYKYVCDEILMPMSGD-ELQTVEIDYLDTWRA 163 Query: 550 LEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKP 651 +E LV G+VRS+G+SNFN +Q+QRI+ +S KP Sbjct: 164 MENLVKLGMVRSIGLSNFNMEQIQRIIQCSSSKP 197 >UniRef50_Q7ZWA4 Cluster: Zgc:56622; n=6; cellular organisms|Rep: Zgc:56622 - Danio rerio (Zebrafish) (Brachydanio rerio) Length = 289 Score = 154 bits (374), Expect = 5e-36 Identities = 72/150 (48%), Positives = 101/150 (67%), Gaps = 1/150 (0%) Frame = +1 Query: 205 QAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQEGVVKREDLFITSKLWNTFHRPDLV 384 +A + AI GYRHI AF Y NE +VG AI+ KIQ+G+++R+D+FI SKLW T H P+ + Sbjct: 4 RACEAAIAAGYRHIDTAFCYRNEVDVGMAIQNKIQQGIIRRQDMFIVSKLWGTHHAPEDI 63 Query: 385 RGALEVSLRNLNIDYLDLYLIHWPQAYKE-DDAIFPTDADGKIQFSDVDYVDTWKALEPL 561 SL +L +DYLD YL+H+P K+ D +FP + DGKI +D+DYVD W+ +E L Sbjct: 64 PVCFNKSLSDLQLDYLDQYLVHFPVGLKKVGDELFP-ERDGKILTTDIDYVDVWRGMEAL 122 Query: 562 VCHGLVRSLGVSNFNSKQLQRILDNASVKP 651 G V+S+GVSNF +Q+ R+L A + P Sbjct: 123 KATGKVKSIGVSNFTMEQIDRLLSVAKIPP 152 Score = 37.5 bits (83), Expect = 0.97 Identities = 15/32 (46%), Positives = 21/32 (65%) Frame = +2 Query: 659 NQVECHPYLNXKRLKQFCEDRDIMITXYSPXG 754 NQVE HPYL L +C+ ++I +T +SP G Sbjct: 155 NQVELHPYLVQSDLIDYCKSKNIALTAHSPFG 186 >UniRef50_Q9VHX4 Cluster: CG2767-PA; n=4; Endopterygota|Rep: CG2767-PA - Drosophila melanogaster (Fruit fly) Length = 329 Score = 154 bits (374), Expect = 5e-36 Identities = 75/184 (40%), Positives = 112/184 (60%), Gaps = 2/184 (1%) Frame = +1 Query: 112 MTSVPVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEA 291 M + T +NG K+PVIGIGTW++ E+ A+ A++ GYRHI A VYGNEK +G Sbjct: 1 MVNTKFLTFNNGEKMPVIGIGTWQASDEEIETAIDAALEAGYRHIDTAPVYGNEKAIGRV 60 Query: 292 IKTKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYK- 468 +K + G VKRE+LFI +K+ +RP V ++ SL +L +DY+DLYL+H P Sbjct: 61 LKRWLDAGKVKREELFIVTKVPPVSNRPHEVEPTIKKSLEDLQLDYVDLYLVHTPFTINI 120 Query: 469 EDDAIFPTDADGKIQFS-DVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASV 645 +D F D +G ++ ++ W A+E LV GL +S+GVSNF+ Q+ R+L N + Sbjct: 121 NEDGSFKLDKEGLMEVDVTTNHAAIWVAMEALVEKGLTKSIGVSNFSKDQVARLLKNCKI 180 Query: 646 KPGH 657 +P + Sbjct: 181 RPAN 184 Score = 37.9 bits (84), Expect = 0.73 Identities = 15/32 (46%), Positives = 20/32 (62%) Frame = +2 Query: 659 NQVECHPYLNXKRLKQFCEDRDIMITXYSPXG 754 NQ+E H YL + L FC+ +I +T YSP G Sbjct: 185 NQIEHHVYLQQRDLVDFCKSENITVTAYSPLG 216 >UniRef50_Q9Y020 Cluster: 3-dehydroecdysone 3beta-reductase precursor; n=1; Spodoptera littoralis|Rep: 3-dehydroecdysone 3beta-reductase precursor - Spodoptera littoralis (Egyptian cotton leafworm) Length = 345 Score = 153 bits (371), Expect = 1e-35 Identities = 76/186 (40%), Positives = 112/186 (60%), Gaps = 9/186 (4%) Frame = +1 Query: 121 VPVTTLSNGAKIPVIGIGTW---------KSKPGEVTQAVKDAIDIGYRHIXCAFVYGNE 273 VP+ + N ++P I +GT+ SK ++ V AID+GYRH A +Y E Sbjct: 22 VPMLKMLNDREMPAIALGTYLGFDKGGAVTSKDKQLRNVVMQAIDLGYRHFDTAAIYNTE 81 Query: 274 KEVGEAIKTKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHW 453 EVGEAI+ KI EGV+KRED+F+T+KLWNT H+ + V A++ +L +DY+DL+L+HW Sbjct: 82 AEVGEAIRMKIDEGVIKREDVFLTTKLWNTHHKREQVAVAMKETLNKTGLDYVDLFLMHW 141 Query: 454 PQAYKEDDAIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILD 633 P A ED S+ DY++TW+A E +V G +S+G+SNFN Q+ +L Sbjct: 142 PIALNED-----------YSHSNTDYLETWRATEEMVKLGYTKSIGLSNFNKLQVATVLQ 190 Query: 634 NASVKP 651 ++KP Sbjct: 191 ECTIKP 196 >UniRef50_Q16K66 Cluster: Aldo-keto reductase; n=2; Aedes aegypti|Rep: Aldo-keto reductase - Aedes aegypti (Yellowfever mosquito) Length = 303 Score = 152 bits (369), Expect = 2e-35 Identities = 90/243 (37%), Positives = 136/243 (55%), Gaps = 3/243 (1%) Frame = +1 Query: 136 LSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQEG 315 L+NG IP IG+GT+K + A+K A++ GYR I AFVY NE+ VG+A++ +G Sbjct: 4 LNNGHSIPPIGLGTYKITGSDGVAAIKSAVEFGYRLIDTAFVYNNEQVVGQALREIFSQG 63 Query: 316 -VVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPT 492 + RED+FI SKL TFHRP+ V +SL L +DY+DLYL+H P A ++ Sbjct: 64 NDINREDVFIVSKLGPTFHRPEAVEKGCRLSLERLGLDYVDLYLMHTPVAARDSG----- 118 Query: 493 DADGKIQFSD-VDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPGH*PGR 669 D + + + D V ++TWKALE GLVRS+GVSNFN +QL I+ + S++P Sbjct: 119 DGNDRSEIDDEVTPLETWKALEECQRKGLVRSIGVSNFNEEQLMEIVTHGSIRPVVNQVE 178 Query: 670 MPSVFKPXAIEAVLRRP*YYDNGVLPRWGXPDRPWAKPGDPHL-MEDPKLKEIADRLGKX 846 F + R + ++ + +P KPG H+ ++ L ++A++ G+ Sbjct: 179 CSIGFHQVKLRKFCNR----EGILIMAYSPLGKP--KPGKKHVFLDSSDLNKMAEKYGRS 232 Query: 847 AAQ 855 AQ Sbjct: 233 PAQ 235 Score = 34.7 bits (76), Expect = 6.8 Identities = 15/34 (44%), Positives = 20/34 (58%) Frame = +2 Query: 653 VTNQVECHPYLNXKRLKQFCEDRDIMITXYSPXG 754 V NQVEC + +L++FC I+I YSP G Sbjct: 173 VVNQVECSIGFHQVKLRKFCNREGILIMAYSPLG 206 >UniRef50_A7CWF9 Cluster: Aldehyde reductase; n=2; Bacteria|Rep: Aldehyde reductase - Opitutaceae bacterium TAV2 Length = 347 Score = 151 bits (367), Expect = 4e-35 Identities = 94/251 (37%), Positives = 133/251 (52%), Gaps = 7/251 (2%) Frame = +1 Query: 121 VPVTTLSNGAKIPVIGIGTWKSK---PGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEA 291 +P TL++GA++P IG+GT+ S PGEV +V A ++GYRH CA VY NE+E+G Sbjct: 16 IPQRTLASGARMPAIGMGTFGSDHAAPGEVAASVYAAAELGYRHFDCAAVYSNEREIGAT 75 Query: 292 IKTKIQEGV-VKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWP-QAY 465 + + ++REDL+ITSKLWN H V A E SLR+L +DYLDLYLIHWP + Sbjct: 76 FRRILTSNTGIRREDLWITSKLWNDKHAEADVIPAFEKSLRDLGLDYLDLYLIHWPFPNF 135 Query: 466 KEDDAIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASV 645 + + + +++ TW+ LE L GLVR +G SN +LQ +L +A V Sbjct: 136 HPPGCDVSSRSPDARPYIHAEFMKTWRQLETLHDRGLVRHIGTSNMTIAKLQLLLRDARV 195 Query: 646 KPGH*PGRMPSVFKPXAIEAVLRRP*YYDNGVLPRWGXPDRPW--AKPGDPHLMEDPKLK 819 +P + F+ A+ +R G P G P RP D +EDP ++ Sbjct: 196 RPAVNEMELHPHFQQPALFDYVRVRNIVPVGYCP-LGSPGRPERDRTAEDTSPLEDPVIQ 254 Query: 820 EIADRLGKXAA 852 IA G A Sbjct: 255 RIAAAHGMHPA 265 >UniRef50_P26690 Cluster: NAD(P)H-dependent 6'-deoxychalcone synthase; n=3; Papilionoideae|Rep: NAD(P)H-dependent 6'-deoxychalcone synthase - Glycine max (Soybean) Length = 315 Score = 151 bits (367), Expect = 4e-35 Identities = 86/237 (36%), Positives = 135/237 (56%), Gaps = 2/237 (0%) Frame = +1 Query: 151 KIPVIGIGTWK--SKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQEGVVK 324 ++PV+G+G+ + + +A+ +A+ GYRH A YG+E+ +GEA+K I G+V Sbjct: 20 RMPVVGMGSAPDFTCKKDTKEAIIEAVKQGYRHFDTAAAYGSEQALGEALKEAIHLGLVS 79 Query: 325 REDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTDADG 504 R+DLF+TSKLW T + P LV AL SL+ L ++YLDLYLIHWP + + FP + + Sbjct: 80 RQDLFVTSKLWVTENHPHLVLPALRKSLKTLQLEYLDLYLIHWPLSSQPGKFSFPIEVED 139 Query: 505 KIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPGH*PGRMPSVF 684 + F D W+++E GL +++GVSNF+ K+LQ +L A+++P M + Sbjct: 140 LLPF---DVKGVWESMEECQKLGLTKAIGVSNFSVKKLQNLLSVATIRPVVDQVEMNLAW 196 Query: 685 KPXAIEAVLRRP*YYDNGVLPRWGXPDRPWAKPGDPHLMEDPKLKEIADRLGKXAAQ 855 + + + +NG++ P R A G +ME+ LKEIA+ GK AQ Sbjct: 197 QQKKLREFCK-----ENGIIVTAFSPLRKGASRGPNEVMENDVLKEIAEAHGKSIAQ 248 >UniRef50_UPI00015B4B22 Cluster: PREDICTED: similar to GA15457-PA; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to GA15457-PA - Nasonia vitripennis Length = 388 Score = 151 bits (365), Expect = 7e-35 Identities = 78/175 (44%), Positives = 110/175 (62%), Gaps = 1/175 (0%) Frame = +1 Query: 136 LSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQEG 315 LS+G +IP +G+GT K E+ A+ A++ GYRHI AF Y NE +G+ +K +G Sbjct: 28 LSSGHEIPAVGLGTSTIKLDEMDNAISSALENGYRHIDTAFSYDNEAAIGKILKKWFDKG 87 Query: 316 VVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAI-FPT 492 KRED+FITSKL + +RP V L+ SL++L +DY+D+YLIH P A KE + + Sbjct: 88 G-KREDIFITSKLPSQGNRPQSVETYLKRSLKDLGLDYVDMYLIHTPFAVKEGENLSSKQ 146 Query: 493 DADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPGH 657 D DG F DVD+ WKA+E V G +S+G+SNFN Q+ I +NA +KP + Sbjct: 147 DKDGNDLFDDVDHKALWKAMERQVKEGRAKSIGLSNFNQSQVLNIYNNAEIKPSN 201 Score = 41.1 bits (92), Expect = 0.079 Identities = 15/31 (48%), Positives = 24/31 (77%) Frame = +2 Query: 662 QVECHPYLNXKRLKQFCEDRDIMITXYSPXG 754 QVE H YL K+L++FC++ +I++T Y+P G Sbjct: 203 QVETHAYLQQKQLRKFCKEHNIVMTAYAPLG 233 >UniRef50_A2EHN6 Cluster: Oxidoreductase, aldo/keto reductase family protein; n=10; Trichomonas vaginalis|Rep: Oxidoreductase, aldo/keto reductase family protein - Trichomonas vaginalis G3 Length = 312 Score = 150 bits (363), Expect = 1e-34 Identities = 91/243 (37%), Positives = 132/243 (54%), Gaps = 8/243 (3%) Frame = +1 Query: 151 KIPVIGIGTWKSK-PGEVTQAVKDAID-IGYRHIXCAFVYGNEKEVGEAIKTKIQEGVVK 324 +IP +G GT+ + P ++ A+ AI+ G RHI AF Y N+ +GE +K +G +K Sbjct: 2 EIPQLGFGTYLANDPAKLKAALHYAIEECGVRHIDTAFAYYNQNVIGETLKEIFAKGKIK 61 Query: 325 REDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYK----EDDAIFPT 492 RED+FIT+KLW T HR DLV L +L L + Y+DL+LIH P A+K +D + P Sbjct: 62 REDMFITTKLWCTHHRKDLVEPELHENLAQLQLSYVDLFLIHQPIAFKSLPAKDGTMMPK 121 Query: 493 DADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKP--GH*PG 666 D GKIQ+ +D ++T+ A+E GL R +GVSNF+ +QL+RI N +KP Sbjct: 122 DEKGKIQYEQIDILETYHAMEECQKKGLTRHIGVSNFSIEQLERIWFNCEIKPYANQVEC 181 Query: 667 RMPSVFKPXAIEAVLRRP*YYDNGVLPRWGXPDRPWAKPGDPHLMEDPKLKEIADRLGKX 846 + FKP + + G P P P L+EDP +K++A K Sbjct: 182 NIYRQFKPLLSYCESHNIYLMAHTTI---GHP--PLKGPFGTSLLEDPVVKQVASEAKKT 236 Query: 847 AAQ 855 +AQ Sbjct: 237 SAQ 239 >UniRef50_A7PNI3 Cluster: Chromosome chr1 scaffold_22, whole genome shotgun sequence; n=2; Vitis vinifera|Rep: Chromosome chr1 scaffold_22, whole genome shotgun sequence - Vitis vinifera (Grape) Length = 360 Score = 149 bits (362), Expect = 2e-34 Identities = 77/173 (44%), Positives = 109/173 (63%), Gaps = 1/173 (0%) Frame = +1 Query: 136 LSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQEG 315 L+ AKIP IG+GTW+S +AVK A+ GYR I CA +YGNE EVGEA+ + G Sbjct: 14 LNTKAKIPAIGLGTWQSGGDLCVEAVKRALSEGYRQIDCAHLYGNEVEVGEAL-AEAFNG 72 Query: 316 VVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTD 495 +KRED+F+TSKL+ T + + + ++ VSL+NL + YLDLYL+HWP DA P Sbjct: 73 SLKREDVFLTSKLYCTMNSLNKIENSVRVSLKNLGVTYLDLYLMHWPDITAFGDATDPPS 132 Query: 496 ADGKIQFSDVDYV-DTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKP 651 G ++ + WKA+E L+ GLVR++GVSNF +Q++ +L A + P Sbjct: 133 NSGNDHRQFLNRLKKAWKAMEGLIELGLVRAIGVSNFGVQQIKELLKFAKIVP 185 Score = 35.9 bits (79), Expect = 3.0 Identities = 14/41 (34%), Positives = 24/41 (58%) Frame = +2 Query: 659 NQVECHPYLNXKRLKQFCEDRDIMITXYSPXGXLPTDPGLS 781 NQV+ HP+ L +FC+ + I ++ ++P G + PG S Sbjct: 188 NQVKLHPFWRQDELVKFCQSKGIHVSAHTPLGVPASGPGPS 228 >UniRef50_Q17G72 Cluster: Aldo-keto reductase; n=9; Endopterygota|Rep: Aldo-keto reductase - Aedes aegypti (Yellowfever mosquito) Length = 316 Score = 149 bits (361), Expect = 2e-34 Identities = 86/242 (35%), Positives = 130/242 (53%), Gaps = 1/242 (0%) Frame = +1 Query: 133 TLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQE 312 T NG +P +G GTW++ EV +A+ +A++ GYRHI A VY NEK +G+ +K + Sbjct: 8 TFENGTTMPALGFGTWRASDEEVEKALNEALEAGYRHIDTAPVYLNEKTIGKVLKEWMDA 67 Query: 313 GVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPT 492 G V R++LFI +KL R V L+ SL +L ++Y+DLY +H P E D F Sbjct: 68 GKVTRDELFIVTKLPPHGTRASTVEKFLKNSLDDLQLEYVDLYHVHVPFTVPEVDGPFLV 127 Query: 493 DADGKIQF-SDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPGH*PGR 669 + DG I + D+V WKA+E + GL R++G+SNFN +Q+QRILDN +KP + Sbjct: 128 E-DGLIVLETTTDHVALWKAMEEVYEAGLARNIGLSNFNQRQIQRILDNCQIKPANLQIE 186 Query: 670 MPSVFKPXAIEAVLRRP*YYDNGVLPRWGXPDRPWAKPGDPHLMEDPKLKEIADRLGKXA 849 + + + P P L+++P +K+IA++LGK Sbjct: 187 NHIYLQQPELVKFCKANGITVTAYSPLGSKGIEKLLGREVPDLLDNPVVKDIAEKLGKSP 246 Query: 850 AQ 855 AQ Sbjct: 247 AQ 248 >UniRef50_Q6RZX1 Cluster: Gld1; n=22; Pezizomycotina|Rep: Gld1 - Trichoderma atroviride (Hypocrea atroviridis) Length = 327 Score = 149 bits (360), Expect = 3e-34 Identities = 90/251 (35%), Positives = 138/251 (54%), Gaps = 10/251 (3%) Frame = +1 Query: 133 TLSNGAKIPVIGIGTWKSK--PGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKI 306 TL+ GAKIP +G GT+ ++ GE AV A+D+GYRH+ CA+ Y NE EVG+AI+ + Sbjct: 16 TLNTGAKIPAVGFGTFANEGAKGETYAAVTKALDVGYRHLDCAWFYLNEDEVGDAIRDFL 75 Query: 307 -QEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWP-QAYKEDDA 480 + V R+DLFI +K+WN H P+ V+ + + S NL +DY+DL+L+HWP A K D Sbjct: 76 ARRPDVTRKDLFICTKVWNHLHEPEDVKWSAKNSCENLKVDYIDLFLVHWPIAAEKNADR 135 Query: 481 IFPTDADGKIQFSDV---DYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKP 651 DGK + + TW+A+E LV G+V+++GVSN+ L+++L+ A +KP Sbjct: 136 TVKIGPDGKYVINKALTENPEPTWRAMEELVDSGIVKAIGVSNWTIPGLKQLLEFARIKP 195 Query: 652 GH*PGRM-PSVFKPXAIEAVLRRP*YYDNGVLPRWGXP--DRPWAKPGDPHLMEDPKLKE 822 + P + +E + N +LP P + + ++P L Sbjct: 196 AVNQIEIHPFLPNTELVEFC------FQNDILPEAYSPLGSQNQVPTTGERVRDNPTLNA 249 Query: 823 IADRLGKXAAQ 855 +ADR G AQ Sbjct: 250 VADRRGSSLAQ 260 Score = 37.1 bits (82), Expect = 1.3 Identities = 15/32 (46%), Positives = 19/32 (59%) Frame = +2 Query: 659 NQVECHPYLNXKRLKQFCEDRDIMITXYSPXG 754 NQ+E HP+L L +FC DI+ YSP G Sbjct: 198 NQIEIHPFLPNTELVEFCFQNDILPEAYSPLG 229 >UniRef50_UPI000023D0F1 Cluster: hypothetical protein FG03517.1; n=1; Gibberella zeae PH-1|Rep: hypothetical protein FG03517.1 - Gibberella zeae PH-1 Length = 364 Score = 148 bits (359), Expect = 3e-34 Identities = 76/166 (45%), Positives = 106/166 (63%) Frame = +1 Query: 154 IPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQEGVVKRED 333 IP G+GTW + G V AV+ A+ GYRHI A ++ NE EVG+ IK V R++ Sbjct: 60 IPAFGLGTWLAGKGVVVPAVEYALKGGYRHIDTALIWRNEDEVGKGIKAS----GVSRDE 115 Query: 334 LFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTDADGKIQ 513 +++T KLWNT HRP+LVR A+E S+ NL ++YLDLYLIH+P A+ + D D Sbjct: 116 IWVTGKLWNTDHRPELVRKAIETSIANLGVEYLDLYLIHYPVAWVPE----TRDVD---- 167 Query: 514 FSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKP 651 ++ +DTWKA+E LV GL R++G SNF K + +IL AS++P Sbjct: 168 -NNTSLIDTWKAMEELVRAGLTRNIGFSNFAPKDINKILKIASIQP 212 >UniRef50_Q0CLQ2 Cluster: Putative uncharacterized protein; n=1; Aspergillus terreus NIH2624|Rep: Putative uncharacterized protein - Aspergillus terreus (strain NIH 2624) Length = 301 Score = 146 bits (354), Expect = 1e-33 Identities = 97/263 (36%), Positives = 137/263 (52%), Gaps = 24/263 (9%) Frame = +1 Query: 136 LSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQEG 315 LS+G +P +G+GTW SKP EV AV+ A+ +GYRHI A Y NE EVG K + Sbjct: 9 LSSGYDMPAVGLGTWLSKPHEVENAVETALRLGYRHIDAAACYLNENEVGNGWK----KS 64 Query: 316 VVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYL----------------- 444 V R+ +FITSKLWNT H PD V A+ +L++L DYLDLYL Sbjct: 65 GVPRDQIFITSKLWNTHHHPDHVEEAVNKTLKDLQTDYLDLYLVFPSLLVLIHDLLSLLT 124 Query: 445 ---IHWPQAYKE-DDAIFPTDADGK-IQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNS 609 IHWP A++ ++ + P D K + +++ DTW ALE LV G VRS+GVSNF Sbjct: 125 NNKIHWPVAFEHTNETLTPIDPVSKRFRLANIPIADTWAALEKLVDAGKVRSIGVSNFTI 184 Query: 610 KQLQRILDNASVKPGH*PGRMPSVFKPXAIEAVLRRP*YYDNGVLPRWGXPDRPWAKP-- 783 ++++ +L A + P ++ + P + L + Y V P Sbjct: 185 EKIEELLKTARIPPA--VNQIEA--HPYLQQPALHK--YLKEKVTNILSVAYSPLGNNIY 238 Query: 784 GDPHLMEDPKLKEIADRLGKXAA 852 P +++DP +KEIA +L K A Sbjct: 239 NAPRVVDDPTVKEIAQKLNKDPA 261 >UniRef50_Q1YPE5 Cluster: Aldehyde reductase; n=7; Bacteria|Rep: Aldehyde reductase - gamma proteobacterium HTCC2207 Length = 330 Score = 146 bits (353), Expect = 2e-33 Identities = 75/186 (40%), Positives = 113/186 (60%), Gaps = 9/186 (4%) Frame = +1 Query: 121 VPVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKT 300 VP +S+ + +P +G+G WK QAV +AI +GYRH+ A YGNE++VGE I Sbjct: 7 VPGVKVSSKS-MPAVGLGLWKITQDSAAQAVYEAIKVGYRHLDSAADYGNEQQVGEGIAR 65 Query: 301 KIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQA--YKED 474 I EG+ RE+L+IT+KLWNT+HR + V A S+ +L +DY+DLYL+H+P A Y + Sbjct: 66 AIAEGLCSREELWITTKLWNTYHRAEHVEAACRRSMDDLGLDYIDLYLVHFPIALRYVDF 125 Query: 475 DAIFPTD-------ADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILD 633 + +P + D ++ V +TW A+E LV GLVR +GV N+++ L ++ Sbjct: 126 NDRYPAEWIFDHSAEDPAMELDQVPLSETWGAMEQLVESGLVRQIGVCNYSAVLLHDLMS 185 Query: 634 NASVKP 651 A +KP Sbjct: 186 YARIKP 191 >UniRef50_Q6CFG7 Cluster: Yarrowia lipolytica chromosome B of strain CLIB122 of Yarrowia lipolytica; n=9; Ascomycota|Rep: Yarrowia lipolytica chromosome B of strain CLIB122 of Yarrowia lipolytica - Yarrowia lipolytica (Candida lipolytica) Length = 337 Score = 146 bits (353), Expect = 2e-33 Identities = 81/184 (44%), Positives = 112/184 (60%), Gaps = 4/184 (2%) Frame = +1 Query: 112 MTSVPVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAI-DIGYRHIXCAFVYGNEKEVGE 288 MTS+ T L+NG IP IG+GTWKS EV AV+ A+ + GYRHI AF Y NE VG Sbjct: 29 MTSLDFT-LNNGKTIPAIGLGTWKSTTEEVAGAVECALTEGGYRHIDTAFNYRNEDAVGL 87 Query: 289 AIKTKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYK 468 IK +++G VKRED+F+T+K+W T+H D V L++SL L +DY+D+ LIHWP Sbjct: 88 GIKRAMEKG-VKREDIFVTTKIWVTYH--DRVEENLDMSLERLGLDYVDMLLIHWPVPLN 144 Query: 469 E--DDAIFPTDADGKIQFSDV-DYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNA 639 +D ++P DG + TWK +E ++ G +S+GVSNF+ L+ +L A Sbjct: 145 PNGNDPVYPLRPDGSRDIDESGSQPKTWKQMEAVLKTGKTKSIGVSNFSIPYLEELLKEA 204 Query: 640 SVKP 651 V P Sbjct: 205 EVVP 208 Score = 37.1 bits (82), Expect = 1.3 Identities = 15/32 (46%), Positives = 21/32 (65%) Frame = +2 Query: 659 NQVECHPYLNXKRLKQFCEDRDIMITXYSPXG 754 NQVE HP L L +FC+ +I++T +SP G Sbjct: 211 NQVELHPLLPQLELMEFCKKNNIVMTAFSPFG 242 >UniRef50_UPI00015B40FA Cluster: PREDICTED: similar to CG2767-PA; n=2; Nasonia vitripennis|Rep: PREDICTED: similar to CG2767-PA - Nasonia vitripennis Length = 356 Score = 145 bits (352), Expect = 2e-33 Identities = 75/187 (40%), Positives = 115/187 (61%), Gaps = 3/187 (1%) Frame = +1 Query: 106 LIMTSVPVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVG 285 +I + LS+G +P+IG+GTW+ P + AV A++ GYRHI AF YGNE+ +G Sbjct: 20 VITSGYKTIKLSSGHDMPMIGLGTWQMPPEAIEVAVTAALESGYRHIDTAFTYGNEEAIG 79 Query: 286 EAIKTKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAY 465 + +K +G KREDLFIT+KL R + V L++SL L ++Y+++YLIH P A+ Sbjct: 80 KTLKKWFDKG-GKREDLFITTKLPPIGMRAEYVESYLKLSLEKLGLEYVNMYLIHKPFAF 138 Query: 466 KEDDAIF--PTDADGKIQF-SDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDN 636 +D + + DG + +D D+V W+A+E V G VRS+G+SNFN QL + ++ Sbjct: 139 VKDKYKYEPALNPDGSVVLDTDTDHVAIWRAMEKQVKAGRVRSIGLSNFNKSQLLNVYEH 198 Query: 637 ASVKPGH 657 A +KP + Sbjct: 199 AEIKPSN 205 >UniRef50_Q6C2L0 Cluster: Yarrowia lipolytica chromosome F of strain CLIB122 of Yarrowia lipolytica; n=3; Yarrowia lipolytica|Rep: Yarrowia lipolytica chromosome F of strain CLIB122 of Yarrowia lipolytica - Yarrowia lipolytica (Candida lipolytica) Length = 324 Score = 145 bits (351), Expect = 3e-33 Identities = 74/178 (41%), Positives = 115/178 (64%), Gaps = 6/178 (3%) Frame = +1 Query: 136 LSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQEG 315 L++G IP +G+GT + G V + V AI GYRHI AF+YG+E +VG+ IK I E Sbjct: 9 LNDGHSIPALGLGT--ASDGNVEEVVYAAIKNGYRHIDTAFIYGSEVDVGKGIKRAIDEE 66 Query: 316 VVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDD----AI 483 +VKRE+LF+T+K+W TF+ + V +L++SL++L++DY+DL L+HWP + D AI Sbjct: 67 LVKRENLFVTTKVWPTFY--NRVSESLDISLKDLSLDYVDLLLVHWPVSLLADSDDPRAI 124 Query: 484 FPTDADGKIQFSDV--DYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKP 651 + + DG +++SD D++ T+K +E G +S+GVSN + L+R+LD P Sbjct: 125 YLVNTDGSVRYSDSLDDWITTYKQIEEEKLSGRTKSIGVSNVSEVYLKRLLDQVKTVP 182 Score = 35.5 bits (78), Expect = 3.9 Identities = 15/32 (46%), Positives = 20/32 (62%) Frame = +2 Query: 659 NQVECHPYLNXKRLKQFCEDRDIMITXYSPXG 754 NQ E HPYL K+ +F E I++T +SP G Sbjct: 185 NQFEIHPYLPQKKEIEFNEKHGILVTAFSPLG 216 >UniRef50_Q03PG5 Cluster: Aldo/keto reductase of diketogulonate reductase family; n=1; Lactobacillus brevis ATCC 367|Rep: Aldo/keto reductase of diketogulonate reductase family - Lactobacillus brevis (strain ATCC 367 / JCM 1170) Length = 268 Score = 144 bits (350), Expect = 4e-33 Identities = 94/244 (38%), Positives = 135/244 (55%), Gaps = 2/244 (0%) Frame = +1 Query: 130 TTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQ 309 T LSNG IP++G GT+ +V A+K A+D GYRH+ CA +YGNE VGEAIK Sbjct: 4 TQLSNGVTIPMLGFGTYLIDSKDVPAAIKTALDAGYRHLDCAHIYGNEPAVGEAIKA--- 60 Query: 310 EGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFP 489 + R DLFITSK+WN D A + +L +L +DYLDLYLIHWP EDD Sbjct: 61 -SGIDRSDLFITSKVWNADQGYDKTLAAFDQTLSDLQLDYLDLYLIHWP---NEDDFELT 116 Query: 490 TDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPGH*PGR 669 +DTW+ LE L VR++GVSNF+ QL+++ + A+VKP Sbjct: 117 --------------LDTWRVLETLYQQKKVRAIGVSNFSEDQLKQVFEMATVKP-----M 157 Query: 670 MPSVFK-PXAIEAVLRRP*YYDNGVLPRWGXPDRPWAKPGDPHL-MEDPKLKEIADRLGK 843 + + + P ++A L + DN ++ + ++ G HL +EDP + ++A++ GK Sbjct: 158 INQIERHPYKVQADLGQ-FDTDNDIV------NEGYSPIGHGHLILEDPVITKLAEKYGK 210 Query: 844 XAAQ 855 AQ Sbjct: 211 SPAQ 214 >UniRef50_Q1U9L6 Cluster: 2,5-didehydrogluconate reductase; n=3; Lactobacillus|Rep: 2,5-didehydrogluconate reductase - Lactobacillus reuteri 100-23 Length = 288 Score = 144 bits (349), Expect = 6e-33 Identities = 81/183 (44%), Positives = 111/183 (60%), Gaps = 1/183 (0%) Frame = +1 Query: 106 LIMTSVPVT-TLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEV 282 L +T++ T L+NG KIP +G GT+++ QAVK+AI+ GYRHI A VYGNE+ V Sbjct: 2 LELTNINSTFNLNNGVKIPCVGYGTFRTPADVAEQAVKEAIETGYRHIDTAAVYGNEEAV 61 Query: 283 GEAIKTKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQA 462 G+ IK + +KREDLF+TSKLWNT + + A + +L L +DYLDLYLIHWP Sbjct: 62 GKGIK----DSGIKREDLFVTSKLWNTNRGYEQTKKAFQETLDRLQMDYLDLYLIHWPAN 117 Query: 463 YKEDDAIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNAS 642 K+ F DA KI +TW+A+E L G +R++GVSNF + ++ A Sbjct: 118 EKQ----FGDDA-AKIN------AETWRAMEDLYNEGKIRAIGVSNFMPHHIAELMKTAK 166 Query: 643 VKP 651 V P Sbjct: 167 VAP 169 >UniRef50_A1D4E3 Cluster: D-xylose reductase (Xyl1), putative; n=5; Pezizomycotina|Rep: D-xylose reductase (Xyl1), putative - Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / NRRL 181)(Aspergillus fischerianus (strain ATCC 1020 / DSM 3700 / NRRL 181)) Length = 321 Score = 144 bits (349), Expect = 6e-33 Identities = 75/183 (40%), Positives = 107/183 (58%), Gaps = 5/183 (2%) Frame = +1 Query: 118 SVPVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIK 297 + P T L++G +P++G G WK + AI GYR A YGNE E G+ + Sbjct: 2 TTPSTKLNSGYDMPLVGFGLWKVNNETCADQIYHAIKAGYRLFDGACDYGNEVEAGKGVA 61 Query: 298 TKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYK-ED 474 IQEG+VKREDLFI SKLWN+FH D V L + +DY DL+++H+P A K D Sbjct: 62 RAIQEGIVKREDLFIVSKLWNSFHDGDRVEPICRKQLADWGLDYFDLFIVHFPIALKYVD 121 Query: 475 DAI-FP---TDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNAS 642 A+ +P + K++FS+ +TW A+E LV L RS+GVSNF+++ L +L A Sbjct: 122 PAVRYPPGWLSENNKLEFSNASIQETWTAMESLVDKKLARSIGVSNFSAQLLMDLLRYAR 181 Query: 643 VKP 651 ++P Sbjct: 182 IRP 184 Score = 34.3 bits (75), Expect = 9.0 Identities = 15/35 (42%), Positives = 20/35 (57%) Frame = +2 Query: 656 TNQVECHPYLNXKRLKQFCEDRDIMITXYSPXGXL 760 T Q+E HPYL +RL + + I +T YS G L Sbjct: 186 TLQIEHHPYLTQERLVTYAQKEGIAVTAYSSFGPL 220 >UniRef50_P28475 Cluster: NADP-dependent D-sorbitol-6-phosphate dehydrogenase; n=71; Magnoliophyta|Rep: NADP-dependent D-sorbitol-6-phosphate dehydrogenase - Malus domestica (Apple) (Malus sylvestris) Length = 310 Score = 142 bits (345), Expect = 2e-32 Identities = 89/249 (35%), Positives = 133/249 (53%), Gaps = 8/249 (3%) Frame = +1 Query: 133 TLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQE 312 TLS+G ++PVIG+G W+ + E+ + + +AI IGYRH CA Y +E +VGEA+ + Sbjct: 5 TLSSGYEMPVIGLGLWRLEKDELKEVILNAIKIGYRHFDCAAHYKSEADVGEALAEAFKT 64 Query: 313 GVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPT 492 G+VKRE+LFIT+K+WN+ H V A + SL L IDYLDLYL+H+P K + Sbjct: 65 GLVKREELFITTKIWNSDH--GHVVEACKNSLEKLQIDYLDLYLVHYPMPTKHNAIGKTA 122 Query: 493 DADGKIQFSDVDYV----DTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPGH* 660 G+ + D+D TW+ +E V GLVRS+G+SN+ + L + +KP Sbjct: 123 SLLGEDKVLDIDVTISLQQTWEGMEKTVSLGLVRSIGLSNYELFLTRDCLAYSKIKPAVS 182 Query: 661 PGRMPSVFKPXAIEAVLRRP*YYDNGVLPRWGXPDRPWAKP----GDPHLMEDPKLKEIA 828 F+ ++ + +GVLP P A G ++DP L ++A Sbjct: 183 QFETHPYFQRDSLVKFCMK-----HGVLPTAHTPLGGAAANKDMFGSVSPLDDPVLNDVA 237 Query: 829 DRLGKXAAQ 855 + GK AQ Sbjct: 238 KKYGKSVAQ 246 >UniRef50_Q6TY50 Cluster: Reductase 2; n=10; Magnoliophyta|Rep: Reductase 2 - Hydrangea macrophylla (Bigleaf hydrangea) Length = 321 Score = 142 bits (344), Expect = 2e-32 Identities = 74/183 (40%), Positives = 116/183 (63%), Gaps = 5/183 (2%) Frame = +1 Query: 118 SVPVTTLSNGA-KIPVIGIGTWKSKPGE---VTQAVKDAIDIGYRHIXCAFVYGNEKEVG 285 ++P LS+G K+PV+G+GT P + V +AV +A+ +GYRH A +Y +E+ +G Sbjct: 4 TIPEVPLSSGGRKMPVLGLGTAADPPVDPETVRKAVTEALKLGYRHFDTAALYNSEQPLG 63 Query: 286 EAIKTKIQEGVVK-REDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQA 462 +AI + EG++K R++LFITSKLW + + V AL+ +L+NL ++Y+D+YLIHWP + Sbjct: 64 DAIAEALGEGLIKSRDELFITSKLWCSDAHRENVEPALQKTLKNLKLEYIDMYLIHWPVS 123 Query: 463 YKEDDAIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNAS 642 K + +P K F +DY W+A+E GL +++GVSNF+ K+L +L NA Sbjct: 124 SKPGNYEYPIK---KEDFLQMDYKSVWEAMEECQKLGLTKAIGVSNFSCKKLSDVLANAK 180 Query: 643 VKP 651 V P Sbjct: 181 VPP 183 >UniRef50_Q5FK98 Cluster: Oxidoreductase; n=8; Lactobacillales|Rep: Oxidoreductase - Lactobacillus acidophilus Length = 285 Score = 141 bits (342), Expect = 4e-32 Identities = 72/174 (41%), Positives = 108/174 (62%), Gaps = 1/174 (0%) Frame = +1 Query: 133 TLSNGAKIPVIGIGTWKSKPGEVTQ-AVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQ 309 TL+NG KIP+IG GTW++ GEV + +V A++ GYRHI A YGNE VG AI Q Sbjct: 11 TLNNGVKIPIIGFGTWQTPDGEVAEESVLAALNCGYRHIDTASAYGNEDSVGRAI----Q 66 Query: 310 EGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFP 489 + + R +LFIT+KLWN+ H + + A++ SL +L +DYLD+YLIHWP D Sbjct: 67 KSGINRHELFITTKLWNSDHGYEKTKKAIDQSLLDLKLDYLDMYLIHWPNPSSMRD---- 122 Query: 490 TDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKP 651 +++++ ++W+A+E V G +R++GVSNF L +++ A +KP Sbjct: 123 -------HWAEIN-AESWRAMEEAVRAGKIRAIGVSNFRKHHLDALMETAEIKP 168 >UniRef50_Q5KI95 Cluster: Aldo-keto reductase, putative; n=14; Dikarya|Rep: Aldo-keto reductase, putative - Cryptococcus neoformans (Filobasidiella neoformans) Length = 353 Score = 141 bits (342), Expect = 4e-32 Identities = 76/187 (40%), Positives = 108/187 (57%), Gaps = 3/187 (1%) Frame = +1 Query: 100 SNLIMTSVPVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKE 279 ++LIM++ L+ GA IP IG+GTW++K GEV QAV A+ GYRHI A Y NE E Sbjct: 29 NSLIMSAPTSFKLNTGASIPAIGLGTWQAKAGEVRQAVAHALKAGYRHIDGALCYQNEDE 88 Query: 280 VGEAIKTKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWP- 456 VG IK + V R ++F+TSK+W+++H D V L+ +L++L DYLDLYLIHWP Sbjct: 89 VGLGIK----DSGVPRSEIFLTSKVWSSYH--DRVEECLDTTLKSLQTDYLDLYLIHWPV 142 Query: 457 -QAYKEDDAIFPTDADGKIQFS-DVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRIL 630 A +FP DG D D TW +E ++ G +++G+SN ++ I+ Sbjct: 143 RLAPNGTHPLFPVKPDGSRNLDWDWDQAKTWAQMEDVLKKGKAKAIGLSNAGIPIIEHII 202 Query: 631 DNASVKP 651 V P Sbjct: 203 KTGKVTP 209 Score = 37.5 bits (83), Expect = 0.97 Identities = 14/32 (43%), Positives = 21/32 (65%) Frame = +2 Query: 659 NQVECHPYLNXKRLKQFCEDRDIMITXYSPXG 754 NQVE HPY L ++C+++ I++ YSP G Sbjct: 212 NQVELHPYCPQHALLKYCKEKGILLEAYSPLG 243 >UniRef50_P23901 Cluster: Aldose reductase; n=9; Poaceae|Rep: Aldose reductase - Hordeum vulgare (Barley) Length = 320 Score = 141 bits (341), Expect = 5e-32 Identities = 73/173 (42%), Positives = 109/173 (63%), Gaps = 1/173 (0%) Frame = +1 Query: 136 LSNGAKIPVIGIGTWKSKPGEVTQAVKDAI-DIGYRHIXCAFVYGNEKEVGEAIKTKIQE 312 L +G +P +G+GTW++ + +V+ AI + GYRH+ A YG EKEVG+ +K ++ Sbjct: 18 LKSGHAMPAVGLGTWRAG-SDTAHSVRTAITEAGYRHVDTAAEYGVEKEVGKGLKAAMEA 76 Query: 313 GVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPT 492 G+ R+DLF+TSK+W T P+ VR ALE +L++L +DY+DLY IHWP K D A P Sbjct: 77 GI-DRKDLFVTSKIWCTNLAPERVRPALENTLKDLQLDYIDLYHIHWPFRLK-DGAHMPP 134 Query: 493 DADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKP 651 +A ++F D WK +E LV GLV+ +GV N+ +L R+L +A + P Sbjct: 135 EAGEVLEF---DMEGVWKEMENLVKDGLVKDIGVCNYTVTKLNRLLRSAKIPP 184 >UniRef50_Q23320 Cluster: Putative uncharacterized protein; n=4; Caenorhabditis|Rep: Putative uncharacterized protein - Caenorhabditis elegans Length = 320 Score = 140 bits (339), Expect = 9e-32 Identities = 72/173 (41%), Positives = 106/173 (61%) Frame = +1 Query: 115 TSVPVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAI 294 + VP+ TLSNG +P IG+GTW+ E +++A+ GYRHI A +Y NE ++G+A+ Sbjct: 3 SKVPIFTLSNGVLMPSIGLGTWQMTGEEGKTVIRNAVLAGYRHIDTATLYQNEHQIGDAL 62 Query: 295 KTKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKED 474 EG++KRED+FIT+K + PD+V AL SL+ L +DY+DLYL H P + K+ Sbjct: 63 AELFAEGILKREDIFITTKAFCHEVAPDVVEEALRNSLKRLRLDYVDLYLAHIPASTKD- 121 Query: 475 DAIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILD 633 DG + SDV D W+ E + GL +++GVSNFN Q+ RI++ Sbjct: 122 --------DGSFR-SDVKVEDIWRGFEKVYGLGLTKAIGVSNFNESQIVRIMN 165 >UniRef50_UPI0000499B0E Cluster: oxidoreductase, aldo/keto reductase family; n=1; Entamoeba histolytica HM-1:IMSS|Rep: oxidoreductase, aldo/keto reductase family - Entamoeba histolytica HM-1:IMSS Length = 307 Score = 140 bits (338), Expect = 1e-31 Identities = 87/241 (36%), Positives = 129/241 (53%), Gaps = 1/241 (0%) Frame = +1 Query: 136 LSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGE-AIKTKIQE 312 L+NG +P IG+GTW + PGEV +AV A++ GYR I CA Y NEKE+GE I+ ++ Sbjct: 8 LNNGKFMPAIGLGTWLAAPGEVGKAVTLALENGYRLIDCARFYKNEKEIGEMGIEPFLKN 67 Query: 313 GVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPT 492 RE+LF+TSKLW + +R + S+++L YLDLYLIHWP A K D + P Sbjct: 68 H--PREELFVTSKLW--MDQVTRIRESCLESIQDLKCKYLDLYLIHWPIALKVDASNPPK 123 Query: 493 DADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPGH*PGRM 672 D F D+D + W+ +E LV GLV+S+G+SNF Q+++I+ +KP + Sbjct: 124 PED----FLDMDITEIWQEMERLVDEGLVKSIGLSNFTIPQIEKIMKMCRIKPVINQVEL 179 Query: 673 PSVFKPXAIEAVLRRP*YYDNGVLPRWGXPDRPWAKPGDPHLMEDPKLKEIADRLGKXAA 852 + + V + P G P A D + ++D + +A + K A Sbjct: 180 NVYLQQNKLREVCKSYNIVVEAYRPIGGKP----ANESDKNCLDDEVVVSLAKKYNKTTA 235 Query: 853 Q 855 Q Sbjct: 236 Q 236 >UniRef50_A6W8E7 Cluster: 2,5-didehydrogluconate reductase; n=3; Actinomycetales|Rep: 2,5-didehydrogluconate reductase - Kineococcus radiotolerans SRS30216 Length = 289 Score = 140 bits (338), Expect = 1e-31 Identities = 92/246 (37%), Positives = 128/246 (52%) Frame = +1 Query: 118 SVPVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIK 297 +VP L++G +IP +G G ++ +PG+ QAVK A+D+GYRHI A +YGNE EV + Sbjct: 11 TVPTILLNDGREIPQLGFGVFQIEPGDTAQAVKTALDLGYRHIDTAQMYGNEAEVAQG-- 68 Query: 298 TKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDD 477 I + V R+++++TSKL N FH PD R A++ S+ L +DLYLIHWP Sbjct: 69 --IADSGVPRDEIWVTSKLNNGFHEPDAARKAVDDSVEKLR-GPIDLYLIHWP------- 118 Query: 478 AIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPGH 657 PT G D+V TWK LE G +RS+GVSNF LQR+ A+V P Sbjct: 119 --LPTLYGG-------DFVSTWKVLEEARAAGKLRSIGVSNFQVNHLQRLAQEATVVPA- 168 Query: 658 *PGRMPSVFKPXAIEAVLRRP*YYDNGVLPRWGXPDRPWAKPGDPHLMEDPKLKEIADRL 837 V E V R + GV W+ +++DP + +A+RL Sbjct: 169 --VNQIEVHPYFGNEEVRRHCGEHQIGV--------EAWSPIAQGKVLDDPTVTAVANRL 218 Query: 838 GKXAAQ 855 GK AQ Sbjct: 219 GKSPAQ 224 >UniRef50_Q9FJK0 Cluster: Aldose reductase-like protein; n=3; core eudicotyledons|Rep: Aldose reductase-like protein - Arabidopsis thaliana (Mouse-ear cress) Length = 316 Score = 140 bits (338), Expect = 1e-31 Identities = 89/245 (36%), Positives = 132/245 (53%), Gaps = 2/245 (0%) Frame = +1 Query: 127 VTTLSNGAKIPVIGIGTW-KSKPGEVT-QAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKT 300 V L G IP++G+GT+ K E T AV AI IGYRH A +YG+E+ +G A+ Sbjct: 5 VARLRCGETIPLLGMGTYCPQKDRESTISAVHQAIKIGYRHFDTAKIYGSEEALGTALGQ 64 Query: 301 KIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDA 480 I G V+R+DLF+TSKLW++ H + AL +L+ + +DYLD YL+HWP K Sbjct: 65 AISYGTVQRDDLFVTSKLWSSDHHDPI--SALIQTLKTMGLDYLDNYLVHWPIKLK-PGV 121 Query: 481 IFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPGH* 660 P + + + D+ +TW+ +E + GL RS+GVSNF+SK++ +LD ASV P Sbjct: 122 SEPIPKEDEFE-KDLGIEETWQGMERCLEMGLCRSIGVSNFSSKKIFDLLDFASVSPSVN 180 Query: 661 PGRMPSVFKPXAIEAVLRRP*YYDNGVLPRWGXPDRPWAKPGDPHLMEDPKLKEIADRLG 840 M +++ + V + +G P G P W G ++E P +K IA + Sbjct: 181 QVEMHPLWRQRKLRKVCEENNIHVSGYSP-LGGPGNCW---GSTAVIEHPIIKSIALKHN 236 Query: 841 KXAAQ 855 AQ Sbjct: 237 ATPAQ 241 >UniRef50_Q01J82 Cluster: OSIGBa0152K17.5 protein; n=28; Magnoliophyta|Rep: OSIGBa0152K17.5 protein - Oryza sativa (Rice) Length = 323 Score = 139 bits (337), Expect = 2e-31 Identities = 89/256 (34%), Positives = 133/256 (51%), Gaps = 8/256 (3%) Frame = +1 Query: 112 MTSVPVTTLSNGA--KIPVIGIGTWKS---KPGEVTQAVKDAIDIGYRHIXCAFVYGNEK 276 M +VP L +GA +P +G+GT S P A A+++G+RH A +YG E Sbjct: 1 MAAVPEVALRHGAGRPMPAVGVGTADSAATSPETKRGAALAALEVGFRHFDTAALYGTEA 60 Query: 277 EVGEAIKTKIQEGVV-KREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHW 453 +GEAI + G+V RE++F+T+KLW T P LV +L SLRNL ++Y+DLYL+HW Sbjct: 61 PLGEAIAEATRRGLVASREEVFVTTKLWCTQCHPGLVLPSLRESLRNLQMEYVDLYLVHW 120 Query: 454 PQAYKEDDAIFPTDADGKIQFSDVDYVDTWKALEPLVCH--GLVRSLGVSNFNSKQLQRI 627 P + K + P + + F D+ W+A+E CH GL +++GVSNF +K L ++ Sbjct: 121 PISVKPGPPMLPVKREDAVPF---DFEGVWRAMEE--CHRLGLAKAIGVSNFTTKHLDKL 175 Query: 628 LDNASVKPGH*PGRMPSVFKPXAIEAVLRRP*YYDNGVLPRWGXPDRPWAKPGDPHLMED 807 L A++ P M V++ + P G + W G+ +ME Sbjct: 176 LAVATIPPAVNQVEMNPVWQQRTVREYCAAKGIRVAAYSPLGG---QNWIGEGN-DVMES 231 Query: 808 PKLKEIADRLGKXAAQ 855 P L +IA GK AQ Sbjct: 232 PVLADIARARGKSIAQ 247 >UniRef50_Q41399 Cluster: Chalcone reductase; n=4; eudicotyledons|Rep: Chalcone reductase - Sesbania rostrata Length = 322 Score = 138 bits (335), Expect = 3e-31 Identities = 85/249 (34%), Positives = 136/249 (54%), Gaps = 4/249 (1%) Frame = +1 Query: 121 VPVTTLSNGAKIPVIGIGTW-KSKPGE--VTQAVKDAIDIGYRHIXCAFVYGNEKEVGEA 291 +P L++G K+PVIG+GT +S+P + DAI +GYRH A VYG E+ +G A Sbjct: 6 IPEVLLNSGHKMPVIGMGTSVESRPSNDVLASIFVDAIQVGYRHFDSASVYGTEEAIGMA 65 Query: 292 IKTKIQEGVVK-REDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYK 468 + I++G++K R+++FITSK WNT DL+ AL+ +L+ L ++Y+DLYLIHWP + Sbjct: 66 VSKAIEQGLIKSRDEVFITSKPWNTDAHHDLIVPALKTTLKKLGMEYVDLYLIHWPVRLR 125 Query: 469 EDDAIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVK 648 D + K D TWKA+E GL +S+G+ N+ +K+L ++L+ A++ Sbjct: 126 HD--LENPVIFSKEDLLPFDIEGTWKAMEECYRLGLAKSIGICNYGTKKLTKLLEIATIP 183 Query: 649 PGH*PGRMPSVFKPXAIEAVLRRP*YYDNGVLPRWGXPDRPWAKPGDPHLMEDPKLKEIA 828 P M ++ + ++ + + P G W G +ME+ L++IA Sbjct: 184 PAVNQVEMNPSWQQGNLREFCKQKGIHVSAWSP-LGAYKIFW---GSGAVMENQILQDIA 239 Query: 829 DRLGKXAAQ 855 GK AQ Sbjct: 240 TAKGKTIAQ 248 >UniRef50_Q88SL1 Cluster: Oxidoreductase; n=51; Lactobacillales|Rep: Oxidoreductase - Lactobacillus plantarum Length = 286 Score = 138 bits (334), Expect = 4e-31 Identities = 76/174 (43%), Positives = 99/174 (56%), Gaps = 1/174 (0%) Frame = +1 Query: 133 TLSNGAKIPVIGIGTWKSKPGEVT-QAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQ 309 TL+NG KIP++G GTW++ G+V +V A+ GYRHI A YGNE+ VG+AI Sbjct: 12 TLNNGTKIPIVGFGTWQTPDGQVAYDSVLAALKAGYRHIDTAAAYGNEESVGKAIA---- 67 Query: 310 EGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFP 489 + V REDLF+T+KLWN H D + AL+ SL L +DY+DLYLIHWP D Sbjct: 68 DSGVAREDLFVTTKLWNADHGYDAAKKALDTSLAKLGLDYVDLYLIHWPNPAAMRDNWEQ 127 Query: 490 TDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKP 651 +A DTW+A+E R++GVSNF K L +L A V P Sbjct: 128 LNA------------DTWRAMEEAYTARKARAIGVSNFRPKHLDALLKTAKVVP 169 >UniRef50_A6WDZ5 Cluster: Aldo/keto reductase; n=5; Bacteria|Rep: Aldo/keto reductase - Kineococcus radiotolerans SRS30216 Length = 343 Score = 138 bits (333), Expect = 5e-31 Identities = 96/247 (38%), Positives = 125/247 (50%), Gaps = 7/247 (2%) Frame = +1 Query: 121 VPVTTLSNGAKIPVIGIGTWKS---KPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEA 291 VP L GA +P IGIGT+ S P EV AV A+ GYR + CA VYGNE +VGEA Sbjct: 13 VPRRELRGGATVPAIGIGTFGSDRYSPAEVAAAVAGAVAAGYRLVDCAAVYGNEAQVGEA 72 Query: 292 IKTKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKE 471 + + GV R++LF+ SK+WN H P ++ SLR+L +D+LD +HWP Sbjct: 73 LAGAVAGGV-DRDELFVVSKVWNDAHAPADAVASVHRSLRDLRLDHLDAVFVHWPFP-NH 130 Query: 472 DDAIFPTDA-DGKIQFSDVD-YVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASV 645 + TDA D + + D D Y+ W ALE LV GLVR LG SN +L +L +A + Sbjct: 131 HPPMADTDARDPRARPYDHDAYLALWGALEGLVDSGLVRHLGTSNTTVAKLDLLLRDARI 190 Query: 646 KPGH*PGRMPSVFKPXAIEAVLRRP*YYDNGVLPRWGXPDRPW--AKPGDPHLMEDPKLK 819 P + F+ + A R G P G P RP PGD EDP + Sbjct: 191 PPALNEMELHPCFQQPELFAHCVRHGIQPVGYSP-LGSPSRPERDRTPGDVVDTEDPVVV 249 Query: 820 EIADRLG 840 IA G Sbjct: 250 RIAREHG 256 >UniRef50_Q4FY75 Cluster: Aldo-keto reductase-like protein; n=5; Trypanosomatidae|Rep: Aldo-keto reductase-like protein - Leishmania major strain Friedlin Length = 372 Score = 138 bits (333), Expect = 5e-31 Identities = 73/178 (41%), Positives = 99/178 (55%), Gaps = 8/178 (4%) Frame = +1 Query: 154 IPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQEGVVKRED 333 IP +G GT++ E T AV A+ GYRH+ CA YGNE VGEA+ ++ +RED Sbjct: 30 IPQLGFGTYRLPVSEATDAVAFALSCGYRHVDCAKAYGNEAAVGEALAQALRTRCTRRED 89 Query: 334 LFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQA------YKEDDAIFPTD 495 LF+TSKLW T PD V A +L L +DYLDLYLIHWP + D+ +P Sbjct: 90 LFVTSKLWPTDQHPDHVEAACRATLAALQLDYLDLYLIHWPVCMRHTPHWTSDEDRYPRH 149 Query: 496 ADGKIQF-SDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDN-ASVKPGH*P 663 DG + V +DTW A+ LV GLV+S+G++N + + ++ A K H P Sbjct: 150 RDGTPAIDTSVTLLDTWTAMNRLVDRGLVKSIGLANCTTAHVNDLVKAVAEAKLAHLP 207 >UniRef50_A2QL02 Cluster: Putative frameshift; n=1; Aspergillus niger|Rep: Putative frameshift - Aspergillus niger Length = 357 Score = 136 bits (329), Expect = 2e-30 Identities = 89/249 (35%), Positives = 132/249 (53%), Gaps = 8/249 (3%) Frame = +1 Query: 133 TLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQE 312 TL+ GAKIP +G+GT++ P + V + G R I A VYG E++VG IK + Sbjct: 39 TLNTGAKIPALGVGTFQD-PDSQEETVCQVLQRGMRLIDTARVYGVEQQVGRGIK----K 93 Query: 313 GVVKREDLFITSKLW-NTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFP 489 V RE++F+ +KLW N FH PD V A++ SLR+L Y+DL L+H+P +K + FP Sbjct: 94 SGVPREEIFLGTKLWCNDFH-PDDVERAVDDSLRDLYTPYVDLLLMHYPCTFKRGEDRFP 152 Query: 490 TDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPGH*PGR 669 DA+G++ + +VDTW+ALE +V G VR++GVSNF+ +++ +L S P Sbjct: 153 RDAEGRMIHGETTFVDTWRALEKVVKTGKVRAIGVSNFSKGEIETLLRETSTVPAVHQME 212 Query: 670 MPSVFKPXAIEAVLRRP*YYDNGVLPRWGXPD----RPWAKPGDPHLM---EDPKLKEIA 828 + + LR + P D W+K H+M + P LKEI Sbjct: 213 VHPYLQQKGFNEWLREKGIHVVQFSPLGNMNDFYRQAGWSKE-IAHMMRVIDQPILKEIG 271 Query: 829 DRLGKXAAQ 855 + GK Q Sbjct: 272 QKYGKSPVQ 280 >UniRef50_P14065 Cluster: Protein GCY; n=13; Saccharomycetales|Rep: Protein GCY - Saccharomyces cerevisiae (Baker's yeast) Length = 312 Score = 136 bits (329), Expect = 2e-30 Identities = 74/180 (41%), Positives = 113/180 (62%), Gaps = 9/180 (5%) Frame = +1 Query: 118 SVPVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIK 297 S + +L+ GA+IP IG+GTW+SK + +AV A+ GYRHI A +Y NE +VG+AIK Sbjct: 8 STKILSLNTGAQIPQIGLGTWQSKENDAYKAVLTALKDGYRHIDTAAIYRNEDQVGQAIK 67 Query: 298 TKIQEGVVKREDLFITSKLWNT-FHRPDLVRGALEVSLRNLNIDYLDLYLIHWP----QA 462 + V RE++F+T+KLW T H P++ AL+ SL+ L +DY+DLYL+HWP A Sbjct: 68 ----DSGVPREEIFVTTKLWCTQHHEPEV---ALDQSLKRLGLDYVDLYLMHWPARLDPA 120 Query: 463 Y--KEDDAIFPTDADGK--IQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRIL 630 Y ED PT DG + ++ +++ TW+ ++ L G +++GVSNF+ L+ +L Sbjct: 121 YIKNEDILSVPTKKDGSRAVDITNWNFIKTWELMQELPKTGKTKAVGVSNFSINNLKDLL 180 Score = 36.3 bits (80), Expect = 2.2 Identities = 15/32 (46%), Positives = 19/32 (59%) Frame = +2 Query: 659 NQVECHPYLNXKRLKQFCEDRDIMITXYSPXG 754 NQVE HP L L FC+ + I++ YSP G Sbjct: 192 NQVEIHPLLPQDELINFCKSKGIVVEAYSPLG 223 >UniRef50_UPI0000519CC2 Cluster: PREDICTED: similar to CG2767-PA; n=1; Apis mellifera|Rep: PREDICTED: similar to CG2767-PA - Apis mellifera Length = 321 Score = 136 bits (328), Expect = 2e-30 Identities = 68/173 (39%), Positives = 106/173 (61%), Gaps = 2/173 (1%) Frame = +1 Query: 136 LSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQEG 315 L NG +P+IG GTW+++ E+ A+ A++ GYRHI A Y NEK +G+ +K Sbjct: 8 LPNGELMPIIGFGTWQAQEKELEDALNIALEAGYRHIDTATSYENEKVIGDVLKNWFDSK 67 Query: 316 VVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAY-KEDDAIFPT 492 +KR D+FI +KL +R + V ++ SL+NL ++YLDLYLIH P + K D + P Sbjct: 68 KLKRSDIFIVTKLPAVGNRAEDVEKWIKTSLQNLRLEYLDLYLIHVPIGFEKVGDILHPF 127 Query: 493 DADGKIQF-SDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVK 648 D +G I+ + ++V+ W +E V G +++G+SNFN Q++RIL N +K Sbjct: 128 DENGHIRLDNSTNHVEIWAEMEKQVKCGRTKAIGLSNFNISQIKRILKNTKMK 180 Score = 37.1 bits (82), Expect = 1.3 Identities = 15/31 (48%), Positives = 19/31 (61%) Frame = +2 Query: 662 QVECHPYLNXKRLKQFCEDRDIMITXYSPXG 754 Q+E H Y K L +FC+ +I IT YSP G Sbjct: 185 QIELHVYFQQKELVKFCKQENIPITAYSPLG 215 >UniRef50_A5E082 Cluster: GCY protein; n=4; Saccharomycetales|Rep: GCY protein - Lodderomyces elongisporus (Yeast) (Saccharomyces elongisporus) Length = 295 Score = 134 bits (325), Expect = 5e-30 Identities = 72/184 (39%), Positives = 109/184 (59%), Gaps = 2/184 (1%) Frame = +1 Query: 100 SNLIMTSVPVTTLSNGAKIPVIGIGTWKSKPGEVT-QAVKDAIDIGYRHIXCAFVYGNEK 276 S+ + + TL+NG KIP IG+GTW + + +A A+ GY+HI A YGNE Sbjct: 2 SSQLSINTKTYTLNNGLKIPAIGLGTWLADEEDAAYKATLTALKNGYKHIDTAAAYGNED 61 Query: 277 EVGEAIKTKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWP 456 +VG AI + V R+++F+T+KLWN H+ GAL+ SL+ L ++Y+DLYLIHWP Sbjct: 62 QVGRAIA----DSGVSRDEIFVTTKLWNDQHKDP--EGALDESLKKLGLEYVDLYLIHWP 115 Query: 457 QAYKEDDAIFPTDADGKIQFSDVDYVDTWKALEPLVCHG-LVRSLGVSNFNSKQLQRILD 633 D + + D D+VDTW+ L+ + G V+++GVSNFN K+L ++L+ Sbjct: 116 ---------LSVDPKTEKPYDDYDFVDTWRNLQKIYKEGKKVKAIGVSNFNKKKLDKLLN 166 Query: 634 NASV 645 + V Sbjct: 167 SEGV 170 Score = 37.1 bits (82), Expect = 1.3 Identities = 16/34 (47%), Positives = 20/34 (58%) Frame = +2 Query: 653 VTNQVECHPYLNXKRLKQFCEDRDIMITXYSPXG 754 V NQ+E HP L L + + +DI IT YSP G Sbjct: 175 VINQIEAHPLLTQPDLFDYLKSKDIYITAYSPLG 208 >UniRef50_A3LTU8 Cluster: D-arabinose dehydrogenase; n=5; Saccharomycetales|Rep: D-arabinose dehydrogenase - Pichia stipitis (Yeast) Length = 326 Score = 134 bits (323), Expect = 8e-30 Identities = 82/212 (38%), Positives = 127/212 (59%), Gaps = 10/212 (4%) Frame = +1 Query: 136 LSNGAKIPVIGIGTWKSK-PGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQE 312 LSNG IP +G+GT + P E+ + V A+ GYRHI A+ YG E+ +G+A+K +E Sbjct: 12 LSNGKTIPALGLGTVPPEDPHELKEQVITAVKAGYRHIDTAWYYGTEEYIGQALKQLFEE 71 Query: 313 GVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIF-- 486 G+VKREDLFIT+K+W +F R +L+ SL +L +DY+DL+L HWP D+ Sbjct: 72 GIVKREDLFITTKVWPSFWRNP--EKSLDKSLADLGLDYVDLFLQHWPVVLHGDENGLPP 129 Query: 487 -PTDADGKIQFSD-----VDYVDTWKALEPLVCH-GLVRSLGVSNFNSKQLQRILDNASV 645 P D DGK+ + D + Y+D + +LE ++ + V+S+GVSN++ +L+++L A+V Sbjct: 130 QPRDKDGKLIYDDDPVSGIKYIDAYHSLEDIMDNTSKVKSIGVSNYSIPKLRKLL--AAV 187 Query: 646 KPGH*PGRMPSVFKPXAIEAVLRRP*YYDNGV 741 + H P + P + L + YDNGV Sbjct: 188 RK-HKPVVNQIEYHPLLPQQDLVKY-CYDNGV 217 Score = 36.7 bits (81), Expect = 1.7 Identities = 15/34 (44%), Positives = 21/34 (61%) Frame = +2 Query: 653 VTNQVECHPYLNXKRLKQFCEDRDIMITXYSPXG 754 V NQ+E HP L + L ++C D + I+ YSP G Sbjct: 193 VVNQIEYHPLLPQQDLVKYCYDNGVHISAYSPVG 226 >UniRef50_Q8WRT0 Cluster: 3-dehydrecdysone 3b-reductase; n=1; Trichoplusia ni|Rep: 3-dehydrecdysone 3b-reductase - Trichoplusia ni (Cabbage looper) Length = 308 Score = 132 bits (320), Expect = 2e-29 Identities = 75/178 (42%), Positives = 107/178 (60%), Gaps = 2/178 (1%) Frame = +1 Query: 124 PVTTLSNGAKIPVIGIGTWK-SKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKT 300 P+ L++G IP + +GT+ +V QAV AI GYRHI A +YGNE+EVG+ I Sbjct: 25 PLKQLNDGNAIPSLALGTFGFGDIPKVRQAVLWAIQAGYRHIDTAALYGNEEEVGKGIAD 84 Query: 301 KIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKED-D 477 IQ+G+VKRE+LF+T+KLWN H V AL SL L + Y+DLYLIH P+A E+ D Sbjct: 85 AIQQGLVKREELFVTTKLWNDKHGRHQVVPALRESLTKLGLSYVDLYLIHSPEATNENGD 144 Query: 478 AIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKP 651 + D+D ++TW +E GL +S+GVSNF++ L R++ ++ P Sbjct: 145 PV------------DIDVLNTWNGMEEAKKLGLAKSIGVSNFDTALLDRLIAGSNTVP 190 >UniRef50_P38115 Cluster: D-arabinose dehydrogenase [NAD(P)+] heavy chain; n=3; Saccharomycetaceae|Rep: D-arabinose dehydrogenase [NAD(P)+] heavy chain - Saccharomyces cerevisiae (Baker's yeast) Length = 344 Score = 132 bits (320), Expect = 2e-29 Identities = 79/187 (42%), Positives = 111/187 (59%), Gaps = 14/187 (7%) Frame = +1 Query: 133 TLSNGAKIPVIGIGTWK--SKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKI 306 +L+NG +IP +G+GT K E QAVK AI GYRHI A+ Y E VGEAIK + Sbjct: 26 SLNNGVRIPALGLGTANPHEKLAETKQAVKAAIKAGYRHIDTAWAYETEPFVGEAIKELL 85 Query: 307 QEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAY---KEDD 477 ++G +KREDLFIT+K+W D V +L SL+ L ++Y+DL L HWP + K+ Sbjct: 86 EDGSIKREDLFITTKVWPVLW--DEVDRSLNESLKALGLEYVDLLLQHWPLCFEKIKDPK 143 Query: 478 AI-----FPTDADGKIQF-SDVDYVDTWKALEPLVC---HGLVRSLGVSNFNSKQLQRIL 630 I P D GK + +D DY++T+K LE + VR++GVSNF+ + L+R++ Sbjct: 144 GISGLVKTPVDDSGKTMYAADGDYLETYKQLEKIYLDPNDHRVRAIGVSNFSIEYLERLI 203 Query: 631 DNASVKP 651 VKP Sbjct: 204 KECRVKP 210 Score = 41.5 bits (93), Expect = 0.060 Identities = 17/32 (53%), Positives = 22/32 (68%) Frame = +2 Query: 659 NQVECHPYLNXKRLKQFCEDRDIMITXYSPXG 754 NQVE HP+L L++FC DI++T YSP G Sbjct: 213 NQVETHPHLPQMELRKFCFMHDILLTAYSPLG 244 >UniRef50_Q5T2L2 Cluster: Aldo-keto reductase family 1 member C-like protein 1; n=14; Eutheria|Rep: Aldo-keto reductase family 1 member C-like protein 1 - Homo sapiens (Human) Length = 302 Score = 132 bits (319), Expect = 2e-29 Identities = 66/141 (46%), Positives = 93/141 (65%), Gaps = 4/141 (2%) Frame = +1 Query: 136 LSNGAKIPVIGIGTWK---SKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKI 306 L++G +PV+G GT+ + + +A K AID+G+RHI A++Y NE+EVG+AI KI Sbjct: 13 LNDGPFMPVLGFGTYAPDHTPKSQAAEATKVAIDVGFRHIDSAYLYQNEEEVGQAIWEKI 72 Query: 307 QEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKE-DDAI 483 +G VKRE++F T KLW TF R +LV ALE SL+ L DY+DL++IH P A K+ + Sbjct: 73 ADGTVKREEIFYTIKLWATFFRAELVHPALERSLKKLGPDYVDLFIIHVPFAMKQPGKEL 132 Query: 484 FPTDADGKIQFSDVDYVDTWK 546 P DA G+I V+ DTW+ Sbjct: 133 LPKDASGEIILETVELCDTWE 153 Score = 45.2 bits (102), Expect = 0.005 Identities = 20/39 (51%), Positives = 26/39 (66%) Frame = +2 Query: 638 PL*NQVTNQVECHPYLNXKRLKQFCEDRDIMITXYSPXG 754 P NQV VECHPYLN +L +FC+ +DI++ YS G Sbjct: 167 PTCNQV---VECHPYLNQSKLLEFCKSKDIVLVAYSALG 202 >UniRef50_Q968S3 Cluster: Aldoketoreductase-like protein; n=1; Orconectes limosus|Rep: Aldoketoreductase-like protein - Orconectes limosus (Spinycheek crayfish) Length = 336 Score = 132 bits (318), Expect = 3e-29 Identities = 86/257 (33%), Positives = 132/257 (51%), Gaps = 9/257 (3%) Frame = +1 Query: 112 MTSVPVTTLSNGAKIPVIGIGTW------KSKPGEVTQAVKDAIDIGYRHIXCAFVYGNE 273 MT +P L++G+ IPV+G+GT K VT ++ A++ GYRH A YGNE Sbjct: 8 MTKIPTILLNSGSHIPVMGLGTGSLGRNGKMSEEAVTAVLETALECGYRHFDSAAYYGNE 67 Query: 274 KEVGEAIKTKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHW 453 +G+ ++ I EG VKRE+LFIT+KL +R V L+ SL NL + Y+DLYL+H+ Sbjct: 68 AIIGQVLRRWISEGKVKREELFITTKLPTRGNREKDVARFLQKSLDNLRLPYVDLYLVHY 127 Query: 454 PQAYKEDDAIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILD 633 P + D AD D W+A+E + G +++G+SNFN+ Q+QRI+ Sbjct: 128 PCGILDTDR-ERLSADEVTVDPTTDIHAIWRAMEAQLAAGKTKNIGLSNFNADQVQRIIK 186 Query: 634 NASVKPGH*PGRMPSVFKPXAIEAVLRRP*YYDNGVLPRWG--XPDRPWAKPGDPH-LME 804 V+P + + A+ A + P G R ++PG+ L+E Sbjct: 187 GCQVRPAVLQVEVHVYMQQGALRAFCAQHDIVVCAFCPLGGPFRLIRKASRPGEVKLLLE 246 Query: 805 DPKLKEIADRLGKXAAQ 855 DP++ ++A K AQ Sbjct: 247 DPQVLDVATAHHKTPAQ 263 >UniRef50_P22045 Cluster: Probable reductase; n=101; cellular organisms|Rep: Probable reductase - Leishmania major Length = 284 Score = 132 bits (318), Expect = 3e-29 Identities = 75/176 (42%), Positives = 103/176 (58%), Gaps = 1/176 (0%) Frame = +1 Query: 127 VTTLSNGAKIPVIGIGTWKSKPGEVTQ-AVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTK 303 + TLSNG K+P G+G W+S GEVT+ AV A+ GYRHI A +Y NE+ VG ++ Sbjct: 8 MVTLSNGVKMPQFGLGVWQSPAGEVTENAVNWALCAGYRHIDTAAIYKNEESVGAGLRAS 67 Query: 304 IQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAI 483 V RED+FIT+KLWNT + A E S + L +DY+DLYLIHWP+ D + Sbjct: 68 ----GVPREDVFITTKLWNTEQGYESTLAAFEESRQKLGVDYIDLYLIHWPRG---KDIL 120 Query: 484 FPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKP 651 +GK Y+D+W+A E L VR++GVSNF+ L+ +L +V P Sbjct: 121 ---SKEGK------KYLDSWRAFEQLYKEKKVRAIGVSNFHIHHLEDVLAMCTVTP 167 Score = 35.9 bits (79), Expect = 3.0 Identities = 18/47 (38%), Positives = 27/47 (57%), Gaps = 2/47 (4%) Frame = +2 Query: 653 VTNQVECHPYLNXKRLKQFCEDRDIMITXYSP--XGXLPTDPGLSLV 787 + NQVE HP N L+ FC+ + I + +SP G L ++P LS + Sbjct: 168 MVNQVELHPLNNQADLRAFCDAKQIKVEAWSPLGQGKLLSNPILSAI 214 >UniRef50_Q7N0E4 Cluster: 2,5-diketo-D-gluconic acid reductase A; n=2; Bacteria|Rep: 2,5-diketo-D-gluconic acid reductase A - Photorhabdus luminescens subsp. laumondii Length = 292 Score = 130 bits (315), Expect = 8e-29 Identities = 72/180 (40%), Positives = 101/180 (56%) Frame = +1 Query: 112 MTSVPVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEA 291 M + P+ L++G +P +G+G+W S ++ + + A+DIGYR I A +Y NEK VG A Sbjct: 1 MDNQPIIRLADGNHMPQLGLGSWASDDQQIAETIHAALDIGYRAIDTAAIYNNEKGVGNA 60 Query: 292 IKTKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKE 471 +QE + RED+F+T+KLWN H R AL SL L +DY+DLYLIHWP Sbjct: 61 ----LQETDIPREDIFVTTKLWNDRHLD--ARAALTESLEKLQLDYVDLYLIHWPAP--- 111 Query: 472 DDAIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKP 651 P D YV W+ L L GL+RS+GVSNF + +QR+++ V P Sbjct: 112 -----PQD----------QYVGAWQQLIELQKEGLIRSIGVSNFQPEHIQRLINETGVHP 156 >UniRef50_Q41E86 Cluster: 2,5-didehydrogluconate reductase; n=2; Bacteria|Rep: 2,5-didehydrogluconate reductase - Exiguobacterium sibiricum 255-15 Length = 274 Score = 130 bits (315), Expect = 8e-29 Identities = 87/242 (35%), Positives = 126/242 (52%), Gaps = 1/242 (0%) Frame = +1 Query: 133 TLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQE 312 TL+NG +P +G G +K EV +AV++A+ +GYR I A +Y NE VG A+K + Sbjct: 5 TLNNGLVMPQLGYGVFKVPEQEVYEAVREALRVGYRSIDTAMIYENEAGVGRALK----D 60 Query: 313 GVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPT 492 + RED+F+T+K+WN + A E SL+ L +DY+DLYLIHWP ++D Sbjct: 61 SGIPREDIFLTTKVWNKDQGYERTLAAFETSLQKLGVDYVDLYLIHWPM--PDEDL---- 114 Query: 493 DADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPGH*PGRM 672 Y+DTW+ALE L G +++GVSNF+ L R+L+ +V P + Sbjct: 115 ------------YMDTWRALEQLYRDGKAKAIGVSNFHIPHLTRVLEEGTVVPAVNQIEL 162 Query: 673 PSVFKPXAIEAVLRRP*YYDNG-VLPRWGXPDRPWAKPGDPHLMEDPKLKEIADRLGKXA 849 AI A ++ NG V+ W P K D + DP + +IA R GK Sbjct: 163 HPFLSQEAIRAFCQK-----NGIVVEAWS----PLMKGRD--ALTDPVITDIAARHGKTP 211 Query: 850 AQ 855 AQ Sbjct: 212 AQ 213 >UniRef50_Q8J0K1 Cluster: 4-dihydromethyltrisporate dehydrogenase; n=2; Parasitella parasitica|Rep: 4-dihydromethyltrisporate dehydrogenase - Parasitella parasitica Length = 321 Score = 130 bits (315), Expect = 8e-29 Identities = 71/174 (40%), Positives = 99/174 (56%), Gaps = 7/174 (4%) Frame = +1 Query: 151 KIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQEGVVKRE 330 K+P+ G G WK + + + AI IGYR A YGNE EVG I I+EG+VKRE Sbjct: 14 KMPLRGFGCWKIEKKDAENTIYQAIKIGYRLFDGACDYGNEVEVGRGINKAIKEGLVKRE 73 Query: 331 DLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHW--PQAYKEDDAIFPTD--- 495 +LFI +KLWNTFH VR A + L++ ++Y DLYLIH+ P Y + +P + Sbjct: 74 ELFIVTKLWNTFHSKQHVRTAFDRQLKDWGLEYFDLYLIHFPIPLQYVDPAVSYPPEWYV 133 Query: 496 --ADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKP 651 AD K+ F + W +E LV L R++GV+NFN + + +L A +KP Sbjct: 134 PHAD-KLNFERSPIHECWAEMEKLVQAKLTRNIGVANFNCQAILDLLSYAKIKP 186 >UniRef50_Q4Q5N9 Cluster: Prostaglandin f synthase, putative; n=7; cellular organisms|Rep: Prostaglandin f synthase, putative - Leishmania major Length = 279 Score = 130 bits (313), Expect = 1e-28 Identities = 86/241 (35%), Positives = 122/241 (50%) Frame = +1 Query: 133 TLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQE 312 TLSNG ++P +GIGTW++K G +K A++ GYRH+ A Y NEK VG+ I E Sbjct: 9 TLSNGVQVPQLGIGTWEAKDGNEVVNIKWAVNAGYRHVDTAHYYKNEKGVGQG----ISE 64 Query: 313 GVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPT 492 V R D+F+T+KLWN H + A E S + L ++Y+DLYLIHWP + Sbjct: 65 CGVPRSDIFVTTKLWNYDHGYESALAAFEQSRQALGVEYVDLYLIHWPGPNR-------- 116 Query: 493 DADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPGH*PGRM 672 Y++TW+A E L VR++GVSNF L +L N +V P M Sbjct: 117 -----------SYIETWRAFEKLYEMKKVRAIGVSNFEPHHLDDLLANCTVPPMVNQVEM 165 Query: 673 PSVFKPXAIEAVLRRP*YYDNGVLPRWGXPDRPWAKPGDPHLMEDPKLKEIADRLGKXAA 852 F+ A+ A N + W RP K L+ +P+L E+A++ + AA Sbjct: 166 HPHFQQKALRAYCAE----KNIAVTAW----RPLGKGA---LLTEPQLVELAEKHKRSAA 214 Query: 853 Q 855 Q Sbjct: 215 Q 215 >UniRef50_A6ESC0 Cluster: ARA1; n=1; unidentified eubacterium SCB49|Rep: ARA1 - unidentified eubacterium SCB49 Length = 280 Score = 128 bits (308), Expect = 5e-28 Identities = 71/173 (41%), Positives = 100/173 (57%), Gaps = 1/173 (0%) Frame = +1 Query: 136 LSNGAKIPVIGIGTWKSKPGEVT-QAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQE 312 L+N IP IG GTW++ G+ A+K AID GY+HI A +Y NEK VG IK E Sbjct: 7 LNNNINIPAIGFGTWQTPDGQTAINAIKTAIDAGYKHIDAAAIYKNEKGVGLGIK----E 62 Query: 313 GVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPT 492 + R+DLF+TSK+WN + A + ++ +L +DYLDLYLIHWP A + Sbjct: 63 ANIDRKDLFVTSKVWNEQRGYENTLKAFDNTINDLQLDYLDLYLIHWPAAAHQ------- 115 Query: 493 DADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKP 651 + Q ++ DTW A+E L G +++LGVSNF L +L +A++KP Sbjct: 116 -FENWKQLNN----DTWSAMEKLYKDGKIKALGVSNFMEHHLTPLLQHATIKP 163 >UniRef50_UPI00015B4912 Cluster: PREDICTED: similar to aldo-keto reductase; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to aldo-keto reductase - Nasonia vitripennis Length = 353 Score = 127 bits (307), Expect = 7e-28 Identities = 80/251 (31%), Positives = 125/251 (49%), Gaps = 8/251 (3%) Frame = +1 Query: 127 VTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKI 306 V LS+G P++G+GT + + A++ G HI +FVY NE+ +G+ +K Sbjct: 30 VYRLSSGHNFPIVGLGTHGLNEDVLETVLTGALEKGIGHIDTSFVYKNEETIGKVLKDWF 89 Query: 307 QEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQA--YKEDDA 480 +G KRED+F+TSKL + P+ V +++SL L + YLD+YLIH P A +KED Sbjct: 90 AKGG-KREDIFVTSKLPYYDNHPESVEKYIKLSLEKLGLQYLDMYLIHAPFAVHHKEDSY 148 Query: 481 IFPTDADGKIQF-SDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPGH 657 T+ DG + + D + WK +E V G +S+G+SNFN Q+ IL A +KP + Sbjct: 149 ELATNEDGSVVLDTQTDPIAVWKEMEKQVKEGRTKSIGLSNFNETQITNILKEAKIKPSN 208 Query: 658 *PGRMPSVFKPXAIEAVLRRP*YYDNGVLPRWGXPDRPWAKPGD-----PHLMEDPKLKE 822 + + + + ++ G P R PG P + + P + E Sbjct: 209 LQVEVHAYHQQKPLIEFCQKNGIIVTGYAPLGSPGARKELHPGQMEEEFPDVFKLPVVNE 268 Query: 823 IADRLGKXAAQ 855 IA + GK Q Sbjct: 269 IAKKHGKSVVQ 279 >UniRef50_Q7PM68 Cluster: ENSANGP00000014386; n=1; Anopheles gambiae str. PEST|Rep: ENSANGP00000014386 - Anopheles gambiae str. PEST Length = 310 Score = 127 bits (307), Expect = 7e-28 Identities = 66/167 (39%), Positives = 94/167 (56%), Gaps = 1/167 (0%) Frame = +1 Query: 154 IPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQE-GVVKRE 330 +P IG+GT+ + +A++ AID+GYR A YGNE VGEAI+ KI+E + R+ Sbjct: 17 LPTIGLGTYSILGADGKEAIRTAIDVGYRMFDTAVAYGNEAIVGEAIREKIRECNNLTRD 76 Query: 331 DLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTDADGKI 510 D FI SKL ++HR DLV ++L L +DY+DLYL+H P A + + Sbjct: 77 DFFIISKLSGSYHRQDLVEKCCRMTLDRLGMDYVDLYLMHTPVALQSEKKCARNGTKLNA 136 Query: 511 QFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKP 651 + + W LE GL RS+GVSNFN Q+ +L +AS+ P Sbjct: 137 IDDSIAPTEAWIGLEQCYQEGLCRSIGVSNFNEHQINALLSDASIVP 183 Score = 35.1 bits (77), Expect = 5.2 Identities = 11/32 (34%), Positives = 22/32 (68%) Frame = +2 Query: 659 NQVECHPYLNXKRLKQFCEDRDIMITXYSPXG 754 NQ+EC N + +++FC+ ++I++ Y+P G Sbjct: 186 NQIECSIGFNQRPMRKFCQQQNILVMGYTPLG 217 >UniRef50_UPI0000D56CE5 Cluster: PREDICTED: similar to CG6084-PA, isoform A; n=1; Tribolium castaneum|Rep: PREDICTED: similar to CG6084-PA, isoform A - Tribolium castaneum Length = 493 Score = 126 bits (305), Expect = 1e-27 Identities = 76/197 (38%), Positives = 110/197 (55%), Gaps = 9/197 (4%) Frame = +1 Query: 292 IKTKIQEGVVKREDLFITSKLWNTFH-RPD---LVRGALEVSLRNLNIDYLDLYLIHWPQ 459 +K +Q G + D+ I S + F+ P+ + SL+NL +DYLD+YL+HWP Sbjct: 231 LKYNVQLGNIVISDMLIESANFFDFYLAPEDMSYISTFSSESLKNLQLDYLDVYLMHWPH 290 Query: 460 AYKEDDAIFPTDAD-GKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDN 636 A KE ++ P D G SDVD+VDTWKA+E + L +S+G+SNFNS Q+ R+L + Sbjct: 291 ALKEGPSLHPIDPKTGLFIPSDVDFVDTWKAMEKMHEKDLTKSIGISNFNSNQIDRLLKS 350 Query: 637 ASVKPGH*PGRMPSVFKPXAIEAVLRRP*YYDNGV----LPRWGXPDRPWAKPGDPHLME 804 A + P P ++ LR+ D G+ G P RPW KPGDP+++ Sbjct: 351 AKIA----PVINQIECHPYLNQSKLRK-FCSDRGITVTSYSPLGSPARPWQKPGDPYVIN 405 Query: 805 DPKLKEIADRLGKXAAQ 855 DPK+KEI ++ GK AQ Sbjct: 406 DPKIKEIGNKYGKSPAQ 422 Score = 108 bits (259), Expect = 5e-22 Identities = 66/180 (36%), Positives = 106/180 (58%) Frame = +1 Query: 112 MTSVPVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEA 291 M +P+ L+NG +IPV G+ + EV + V+ + YR + C+ ++ NEK G A Sbjct: 5 MRDIPIAKLNNGIEIPVFGLAAPQDF-FEV-ENVQLVVSSNYRLMDCS-IFENEKRFGVA 61 Query: 292 IKTKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKE 471 ++ I+ G ++R+DLF+ SK T + +LV+ AL +L+ L + YLDLYLI P A K Sbjct: 62 LQQLIEGGKIRRKDLFLMSKFCCT-NTTNLVKAALLDTLKKLQVAYLDLYLIERPPACK- 119 Query: 472 DDAIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKP 651 D + ++TW+A+E L L R++G+SNFNSKQ++RIL+N +++P Sbjct: 120 ----------------DHNLIETWEAMEGLYSEKLTRAIGLSNFNSKQIERILENCTIRP 163 Score = 56.0 bits (129), Expect = 3e-06 Identities = 21/34 (61%), Positives = 26/34 (76%) Frame = +2 Query: 653 VTNQVECHPYLNXKRLKQFCEDRDIMITXYSPXG 754 V NQ+ECHPYLN +L++FC DR I +T YSP G Sbjct: 356 VINQIECHPYLNQSKLRKFCSDRGITVTSYSPLG 389 Score = 45.6 bits (103), Expect = 0.004 Identities = 15/32 (46%), Positives = 23/32 (71%) Frame = +2 Query: 659 NQVECHPYLNXKRLKQFCEDRDIMITXYSPXG 754 NQ++CHPYLN +L+++C + I + YSP G Sbjct: 166 NQIQCHPYLNQAKLRKYCSNNGIAVISYSPLG 197 >UniRef50_Q01HB5 Cluster: OSIGBa0136O08-OSIGBa0153H12.9 protein; n=4; Oryza sativa|Rep: OSIGBa0136O08-OSIGBa0153H12.9 protein - Oryza sativa (Rice) Length = 337 Score = 126 bits (305), Expect = 1e-27 Identities = 75/184 (40%), Positives = 105/184 (57%), Gaps = 5/184 (2%) Frame = +1 Query: 115 TSVPVTTLSNGAKIPVIGIGTWKSKP-GEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEA 291 T+VP TL++G +PV+G GT S P ++ + A+ +GYRH+ A VYG E VG A Sbjct: 18 TAVPCVTLNSGHAMPVLGFGTGSSTPPADLAATIAHAVRLGYRHLDTAAVYGTEGAVGAA 77 Query: 292 IKTKIQEGVV-KREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAY- 465 + ++ G V R +LF+T+KL P V AL SL L +DY+DL+LIHWP A Sbjct: 78 VAEAVRCGAVASRGELFVTTKLSMADAHPPRVVAALRESLSRLGLDYVDLFLIHWPVAIG 137 Query: 466 KEDDAIFPTDADGKIQFSDVDYVDTWKALEPLVCH--GLVRSLGVSNFNSKQLQRILDNA 639 K+D A T D D W+ +E CH GL RS+GVSNF++ ++ R+L A Sbjct: 138 KKDAAGELTWDDLSRGLVPFDMEGVWRGMEE--CHRLGLARSIGVSNFSAAKMSRLLALA 195 Query: 640 SVKP 651 +V P Sbjct: 196 AVPP 199 >UniRef50_Q7G764 Cluster: Probable NAD(P)H-dependent oxidoreductase 1; n=32; Eukaryota|Rep: Probable NAD(P)H-dependent oxidoreductase 1 - Oryza sativa subsp. japonica (Rice) Length = 321 Score = 126 bits (305), Expect = 1e-27 Identities = 86/256 (33%), Positives = 138/256 (53%), Gaps = 8/256 (3%) Frame = +1 Query: 112 MTSVPVTTLSNGAK-IPVIGIGTWK---SKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKE 279 M ++P S + +P +G+GT + + T A+ AI++GYRH A +Y E Sbjct: 1 MATIPEVPASELIQTMPRVGMGTAAFPFTSSEDTTAAMLRAIELGYRHFDTARIYATEGC 60 Query: 280 VGEAIKTKIQEGVV-KREDLFITSKLW-NTFHRPDLVRGALEVSLRNLNIDYLDLYLIHW 453 VGEA+ ++ G++ R D+F+TSK+W + H +V A E +LRNL +DY+DL L+HW Sbjct: 61 VGEAVAEAVRRGLIASRADVFVTSKIWCSDLHAGRVVPAARE-TLRNLGMDYVDLLLVHW 119 Query: 454 PQAYKEDDAIFPTDADGKIQFSDVDYVDTWKALEPLVCH--GLVRSLGVSNFNSKQLQRI 627 P + + FP + + D++ V W+ +E CH GL R++GVSNF++K+L+++ Sbjct: 120 PVSLTPGNYDFPFPKEVILPSFDMEGV--WRGMEE--CHRLGLARAIGVSNFSAKKLEQL 175 Query: 628 LDNASVKPGH*PGRMPSVFKPXAIEAVLRRP*YYDNGVLPRWGXPDRPWAKPGDPHLMED 807 L A+V+P + +++ + V RR G P G PW G +M+ Sbjct: 176 LSLAAVRPAVNQVEVNPMWQQRTLREVCRREGVQLCGYSP-LGAKGTPW---GSAAVMDS 231 Query: 808 PKLKEIADRLGKXAAQ 855 L+EIA GK AQ Sbjct: 232 GVLQEIAGAKGKTLAQ 247 >UniRef50_Q03TW0 Cluster: Aldo/keto reductase of diketogulonate reductase family; n=1; Lactobacillus brevis ATCC 367|Rep: Aldo/keto reductase of diketogulonate reductase family - Lactobacillus brevis (strain ATCC 367 / JCM 1170) Length = 293 Score = 126 bits (304), Expect = 2e-27 Identities = 73/183 (39%), Positives = 107/183 (58%), Gaps = 1/183 (0%) Frame = +1 Query: 106 LIMTSVPVTTLSNGAKIPVIGIGTWKSKPGEVTQ-AVKDAIDIGYRHIXCAFVYGNEKEV 282 ++ +P ++NG +IP +G+G ++ E T+ A+K A+ GYRHI A YGNE+ V Sbjct: 6 ILHNDIPDLPMNNGHQIPQLGLGVFQVDNAEDTKNAIKWALAAGYRHIDTAAYYGNEQWV 65 Query: 283 GEAIKTKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQA 462 GEAI+ E V R+ +F+TSKLWN+ D + A + +L L +DYLDLYLIHWP Sbjct: 66 GEAIR----ESDVPRDQIFVTSKLWNSVRGYDETQAAFQETLDKLGLDYLDLYLIHWP-- 119 Query: 463 YKEDDAIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNAS 642 A G Y+D+W+A+E L G ++++GVSNFN Q+ IL + + Sbjct: 120 -----------APG--------YLDSWRAMEDLYKAGKIKNIGVSNFNQTQMADILAHGT 160 Query: 643 VKP 651 VKP Sbjct: 161 VKP 163 >UniRef50_Q8ZI40 Cluster: 2,5-diketo-D-gluconic acid reductase A; n=74; Bacteria|Rep: 2,5-diketo-D-gluconic acid reductase A - Yersinia pestis Length = 277 Score = 126 bits (303), Expect = 2e-27 Identities = 73/181 (40%), Positives = 102/181 (56%), Gaps = 1/181 (0%) Frame = +1 Query: 112 MTSVPVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEA 291 MT P+ L +G +P +G+G W++ E AV A+++GYR I A +Y NE+ VG+A Sbjct: 1 MTMQPLIKLYDGRLMPQLGLGVWQASIQETELAVSKALEVGYRSIDTAAIYKNEEGVGKA 60 Query: 292 IKTKIQEGVVKREDLFITSKLWN-TFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYK 468 +K V R++LFIT+KLWN H P + ALE SL+ L +DY+DLYLIHWP K Sbjct: 61 LKA----AAVARDELFITTKLWNDDQHNP---QQALETSLQKLQLDYVDLYLIHWPDP-K 112 Query: 469 EDDAIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVK 648 +D YV W+ L L GL+RS+GV NF+ LQR++D + Sbjct: 113 QD-----------------HYVSAWRELVTLKEQGLIRSIGVCNFHIPHLQRLIDETGIA 155 Query: 649 P 651 P Sbjct: 156 P 156 >UniRef50_Q9ZBW7 Cluster: Putative oxidoreductase; n=2; Actinomycetales|Rep: Putative oxidoreductase - Streptomyces coelicolor Length = 277 Score = 125 bits (301), Expect = 4e-27 Identities = 72/179 (40%), Positives = 98/179 (54%) Frame = +1 Query: 115 TSVPVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAI 294 + VP L+NG ++P +G G W+ + AV A++ GYR I A +YGNE+ G AI Sbjct: 3 SKVPPIILNNGVEMPQLGFGVWQVPDDDAQTAVALALEAGYRSIDTAAIYGNEEGTGRAI 62 Query: 295 KTKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKED 474 G+ REDLF+T+KLWN+ D A + S+ L ++YLDLYLIHWP KE Sbjct: 63 AAS---GLA-REDLFVTTKLWNSDQGYDSTLRAFDTSMAKLGLEYLDLYLIHWPMPAKE- 117 Query: 475 DAIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKP 651 YVDT+KA E L+ G VR++GVSNF + L+R+ SV P Sbjct: 118 -----------------RYVDTYKAFEKLLADGRVRAIGVSNFLPEHLERLTAETSVIP 159 >UniRef50_Q7G765 Cluster: Probable NAD(P)H-dependent oxidoreductase 2; n=6; Magnoliophyta|Rep: Probable NAD(P)H-dependent oxidoreductase 2 - Oryza sativa subsp. japonica (Rice) Length = 322 Score = 124 bits (300), Expect = 5e-27 Identities = 86/241 (35%), Positives = 126/241 (52%), Gaps = 7/241 (2%) Frame = +1 Query: 154 IPVIGIGTWK---SKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQEGVV- 321 +P IG+GT + E T A+ AI++GYRH A +Y E V EA+ ++ G+V Sbjct: 18 MPRIGMGTAAFPFTSSEETTAALLRAIELGYRHFDTARLYATEGCVSEAVAEAVRRGLVA 77 Query: 322 KREDLFITSKLW-NTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTDA 498 R D+F+TSKLW + H +V A E +LRNL +DY+DL L+HWP FP Sbjct: 78 SRADVFVTSKLWCSDLHAGRVVPAARE-TLRNLGMDYVDLLLVHWPATVAPGSYDFPFPK 136 Query: 499 DGKIQFSDVDYVDTWKALEPLVCH--GLVRSLGVSNFNSKQLQRILDNASVKPGH*PGRM 672 + D++ V W+ +E CH GL R++GVSNF++K+L+++L A V+P M Sbjct: 137 EEMAPAFDMEGV--WRGMEE--CHRLGLARAIGVSNFSAKKLEQLLSFAVVRPAANQVEM 192 Query: 673 PSVFKPXAIEAVLRRP*YYDNGVLPRWGXPDRPWAKPGDPHLMEDPKLKEIADRLGKXAA 852 +++ + V RR G P G PW G +M+ L +IA GK A Sbjct: 193 NPMWQQRTLREVCRREGVQLCGYSP-LGAKGTPW---GSAAVMDSGVLHDIAQTKGKTLA 248 Query: 853 Q 855 Q Sbjct: 249 Q 249 >UniRef50_P70883 Cluster: AkrI; n=1; Butyrivibrio fibrisolvens|Rep: AkrI - Butyrivibrio fibrisolvens Length = 172 Score = 124 bits (298), Expect = 9e-27 Identities = 69/167 (41%), Positives = 93/167 (55%), Gaps = 1/167 (0%) Frame = +1 Query: 136 LSNGAKIPVIGIGTWKSKP-GEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQE 312 L+NG IP+ G GT+K K E +V+ A+ GYRHI A Y NEK V AIK ++E Sbjct: 10 LNNGTAIPMFGYGTYKIKDQNEAYNSVRLALKNGYRHIDTAAFYENEKFVANAIKDFMEE 69 Query: 313 GVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPT 492 KRED+F+TSK W T D A E ++ + +DYLDLYL+HWP +Y DD T Sbjct: 70 SQTKREDIFVTSKAWKTELGYDKTLAAFEKTMNEMQMDYLDLYLVHWPASYAFDDDWENT 129 Query: 493 DADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILD 633 + TWKA+ + G V+++GVSNF + L I+D Sbjct: 130 NRQ------------TWKAMTEIYKSGRVKAIGVSNFLTHHLDTIID 164 >UniRef50_Q9HGY0 Cluster: Glycerol dehydrogenase; n=8; Saccharomycetaceae|Rep: Glycerol dehydrogenase - Zygosaccharomyces rouxii (Candida mogii) Length = 310 Score = 124 bits (298), Expect = 9e-27 Identities = 69/187 (36%), Positives = 107/187 (57%), Gaps = 7/187 (3%) Frame = +1 Query: 109 IMTSVPVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGE 288 + S L+ G IP +G+GTW+SK E +AV +A+ GYRHI A VYGNE EVG+ Sbjct: 4 LQNSTSTLKLNTGQTIPQVGLGTWRSKENEGYKAVIEALKAGYRHIDGAAVYGNEGEVGK 63 Query: 289 AIKTKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYK 468 A IQ+ V R ++F+T+KLW T R + AL+ SL+ L +DY+ LYL+HWP + Sbjct: 64 A----IQDSGVPRNEIFLTTKLWCTHQRNP--QEALDQSLQRLGLDYVGLYLVHWPVPLR 117 Query: 469 EDDA------IFPTDADGKIQFS-DVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRI 627 ++ F DG + +++ TW+ ++ L+ G +++GVSNF+ L+ + Sbjct: 118 TENIKDGNLFQFAEKPDGSKDVDLEWNFIKTWELMQKLLESGKTKAIGVSNFSVNNLKDL 177 Query: 628 LDNASVK 648 L + K Sbjct: 178 LAAPTTK 184 Score = 38.3 bits (85), Expect = 0.55 Identities = 16/32 (50%), Positives = 21/32 (65%) Frame = +2 Query: 659 NQVECHPYLNXKRLKQFCEDRDIMITXYSPXG 754 NQVE HP L + L Q+C ++ I+I YSP G Sbjct: 190 NQVEFHPLLPQEELIQYCSEKGIVIEAYSPLG 221 >UniRef50_Q9X0A2 Cluster: Oxidoreductase, aldo/keto reductase family; n=21; Bacteria|Rep: Oxidoreductase, aldo/keto reductase family - Thermotoga maritima Length = 286 Score = 123 bits (297), Expect = 1e-26 Identities = 83/246 (33%), Positives = 131/246 (53%), Gaps = 1/246 (0%) Frame = +1 Query: 121 VPVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKT 300 VP TL+NG ++P++G G ++ P + + V +AI +GYR I A Y NE+ VG AIK Sbjct: 3 VPKVTLNNGVEMPILGYGVFQIPPEKTEECVYEAIKVGYRLIDTAASYMNEEGVGRAIKR 62 Query: 301 KIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDA 480 I EG+V+RE+LF+T+KLW + + + A E SL+ L ++Y+DLYLIH P Sbjct: 63 AIDEGIVRREELFVTTKLWVSDVGYESTKKAFEKSLKKLQLEYIDLYLIHQP-------- 114 Query: 481 IFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPGH* 660 F DV WKA+E + GLVR++GVSNF +L ++ + + P Sbjct: 115 -----------FGDVHC--AWKAMEEMYKDGLVRAIGVSNFYPDRLMDLMVHHEIVPAVN 161 Query: 661 PGRMPSVFKPXAIEAVLRRP*YYDNGVLPR-WGXPDRPWAKPGDPHLMEDPKLKEIADRL 837 + ++ +R + + P WG P+A+ G ++ ++ L+ IA++ Sbjct: 162 QIEIHPFYQRQEEIEFMR-----NYNIQPEAWG----PFAE-GRKNIFQNGVLRSIAEKY 211 Query: 838 GKXAAQ 855 GK AQ Sbjct: 212 GKTVAQ 217 >UniRef50_Q7VG53 Cluster: Aldo-keto reductase; n=28; Bacteria|Rep: Aldo-keto reductase - Helicobacter hepaticus Length = 292 Score = 123 bits (297), Expect = 1e-26 Identities = 70/173 (40%), Positives = 101/173 (58%) Frame = +1 Query: 133 TLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQE 312 TL+NG KIP +G+GTW+ V AV++A +GYRHI A YGNE+ VGEA++ + Sbjct: 16 TLNNGNKIPKLGLGTWRIDDNVVEAAVREAFKVGYRHIDTAQAYGNERGVGEAVR----K 71 Query: 313 GVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPT 492 +KRE+LFITSK+ + +++ SL+ + +D++DL LIH PQ P Sbjct: 72 SKIKREELFITSKIRAEYKDYKSASASIDTSLKTMKLDFIDLMLIHSPQ---------PW 122 Query: 493 DADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKP 651 ++ K + + V+ + ALE G VRS+GVSNF K L+ IL N KP Sbjct: 123 NSFRKGDYFK-ENVEVYNALEDAQKAGKVRSIGVSNFLQKDLENILKNCKTKP 174 >UniRef50_Q05KR9 Cluster: Benzil reductase; n=5; Bacillales|Rep: Benzil reductase - Bacillus subtilis Length = 276 Score = 123 bits (297), Expect = 1e-26 Identities = 76/173 (43%), Positives = 98/173 (56%), Gaps = 1/173 (0%) Frame = +1 Query: 136 LSNGAKIPVIGIGTWKSKPG-EVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQE 312 L NG ++P G+G +K + G E T++VK AI GYR I A +Y NE+ VG IK E Sbjct: 11 LHNGVEMPWFGLGVFKVENGNEATESVKAAIKNGYRSIDTAAIYKNEEGVGIGIK----E 66 Query: 313 GVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPT 492 V RE+LFITSK+WN + A E SL L +DYLDLYLIHWP Sbjct: 67 SGVAREELFITSKVWNEDQGYETTLAAFEKSLERLQLDYLDLYLIHWP------------ 114 Query: 493 DADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKP 651 GK + Y DTW+ALE L G +R++GVSNF L+ +L +A +KP Sbjct: 115 ---GKDK-----YKDTWRALEKLYKDGKIRAIGVSNFQVHHLEELLKDAEIKP 159 >UniRef50_A6RKL9 Cluster: Putative uncharacterized protein; n=3; Sclerotiniaceae|Rep: Putative uncharacterized protein - Botryotinia fuckeliana B05.10 Length = 360 Score = 123 bits (296), Expect = 2e-26 Identities = 68/170 (40%), Positives = 100/170 (58%), Gaps = 3/170 (1%) Frame = +1 Query: 157 PVIGIGTWKSK--PGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQEGVVKRE 330 P+IG GTW K P T+AV AI+IGYR I CA VYGNE VG I+ ++ +KRE Sbjct: 40 PLIGFGTWNLKVSPENTTEAVAYAIEIGYRQIDCAAVYGNEVAVGRGIEEGLKRAGLKRE 99 Query: 331 DLFITSKLWNTFHRP-DLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTDADGK 507 D+++TSKLWN H + V L +L++L ++YLDLYLIHWP + + A Sbjct: 100 DIWVTSKLWNDHHGSYENVEKGLNQTLQDLGLEYLDLYLIHWPIGFSSNGA--------- 150 Query: 508 IQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPGH 657 ++D+V T+K++ L V ++GVSNF+ QL+ ++ ++ H Sbjct: 151 ---KNLDHVQTYKSMISLP-KSRVLNIGVSNFSPLQLKNVVSTGTIPYMH 196 >UniRef50_Q03XK0 Cluster: Aldo/keto reductase of diketogulonate reductase family; n=3; Lactobacillales|Rep: Aldo/keto reductase of diketogulonate reductase family - Leuconostoc mesenteroides subsp. mesenteroides (strain ATCC 8293 /NCDO 523) Length = 292 Score = 122 bits (295), Expect = 2e-26 Identities = 70/174 (40%), Positives = 102/174 (58%), Gaps = 1/174 (0%) Frame = +1 Query: 133 TLSNGAKIPVIGIGTWK-SKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQ 309 TL++G ++P++G G ++ + G QAV DAI GYR I A YGNE+EVGEAI I Sbjct: 5 TLASGIEMPLLGFGVFQVQEKGAAKQAVLDAIKTGYRLIDTAASYGNEREVGEAILEAIN 64 Query: 310 EGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFP 489 +G+VKRE+LF+TSK+W A++ SL+ LN+DYLDLYLIH P Sbjct: 65 QGIVKREELFVTSKMWVQDVSAQQATAAIQSSLQRLNLDYLDLYLIHQP----------- 113 Query: 490 TDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKP 651 ++DV W+A+E G ++++GVSNF+ QL + + + +KP Sbjct: 114 --------YNDV--FGAWRAMESAYRSGQLKAIGVSNFDIAQLTNLAEFSDIKP 157 >UniRef50_Q7R2T6 Cluster: GLP_291_56367_57278; n=1; Giardia lamblia ATCC 50803|Rep: GLP_291_56367_57278 - Giardia lamblia ATCC 50803 Length = 303 Score = 122 bits (295), Expect = 2e-26 Identities = 64/169 (37%), Positives = 92/169 (54%), Gaps = 4/169 (2%) Frame = +1 Query: 157 PVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQEGV--VKRE 330 P +G GT+ + E A++ A+ +GYRH CA+ YGNE+ +GE K + VKRE Sbjct: 6 PCVGFGTYLVEDPE---AIRSAVKLGYRHFDCAYRYGNERMIGEVFKEIFNDDSYGVKRE 62 Query: 331 DLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKE--DDAIFPTDADG 504 DL+I SKLW FH P+ V + +LR+L ++YLD++L+HWP A K D +D G Sbjct: 63 DLWIVSKLWPNFHEPEKVAYQISETLRDLQLEYLDVFLMHWPLAIKHLADRDYASSDGKG 122 Query: 505 KIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKP 651 TW+A+E V R +GVSN + L +L +KP Sbjct: 123 GTLLGTTPIRKTWEAMEACVDKKQTRFIGVSNMGTAMLVDLLSYCRIKP 171 Score = 35.9 bits (79), Expect = 3.0 Identities = 15/33 (45%), Positives = 17/33 (51%) Frame = +2 Query: 656 TNQVECHPYLNXKRLKQFCEDRDIMITXYSPXG 754 TNQ E PY RL +FC I +T Y P G Sbjct: 173 TNQFESQPYFPNDRLIEFCNSNGIYVTAYRPLG 205 >UniRef50_UPI00006CD296 Cluster: oxidoreductase, aldo/keto reductase family protein; n=1; Tetrahymena thermophila SB210|Rep: oxidoreductase, aldo/keto reductase family protein - Tetrahymena thermophila SB210 Length = 295 Score = 122 bits (294), Expect = 3e-26 Identities = 65/175 (37%), Positives = 104/175 (59%), Gaps = 1/175 (0%) Frame = +1 Query: 130 TTLSNGAKIPVIGIGTWKS-KPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKI 306 T L NG+K+PV G+GT+K E+ ++ A+D+GYRHI A +Y NEK++G+A++ Sbjct: 8 TELCNGSKLPVFGLGTYKVVSKEEMVTFLRTALDLGYRHIDTAIMYENEKQIGDALQEIY 67 Query: 307 QEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIF 486 +EG KREDLF+ +KL++ ++ V + SL+NL +Y+DLYL+H+ + Sbjct: 68 KEGKYKREDLFLVTKLFS--NKNTKVEDQVRQSLQNLQTNYIDLYLLHYASSP------- 118 Query: 487 PTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKP 651 PTD + + + W E LV GL+R++G+SNFN + L + +KP Sbjct: 119 PTD---QFELTHKPVFQVWAEFEELVQKGLIRNIGISNFNVQMLLDLYSYCKIKP 170 >UniRef50_Q8F1G4 Cluster: Aldehyde reductase; n=8; Bacteria|Rep: Aldehyde reductase - Leptospira interrogans Length = 278 Score = 122 bits (294), Expect = 3e-26 Identities = 69/173 (39%), Positives = 100/173 (57%), Gaps = 1/173 (0%) Frame = +1 Query: 136 LSNGAKIPVIGIGTWKSKPG-EVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQE 312 L+NG +P++G+G WK+K G E +AV +A++ GYRHI A +Y NE +VG+AI+ E Sbjct: 14 LNNGISMPILGLGVWKTKSGKECKEAVLNALEAGYRHIDTARIYDNEVDVGQAIR----E 69 Query: 313 GVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPT 492 + R+++FIT+KLWN D R ALE SL L ID++DLYLIH+P K Sbjct: 70 SGIPRKEIFITTKLWNADQGSDKTRKALENSLDRLGIDFVDLYLIHFPVTSKR------- 122 Query: 493 DADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKP 651 +D+WK LE L L +++GVSN+ L +L N+ + P Sbjct: 123 -------------MDSWKELEKLYHDKLCKAIGVSNYTIIHLTELLKNSQITP 162 Score = 35.9 bits (79), Expect = 3.0 Identities = 14/30 (46%), Positives = 19/30 (63%) Frame = +2 Query: 659 NQVECHPYLNXKRLKQFCEDRDIMITXYSP 748 NQVE HP+LN L ++C+ I + YSP Sbjct: 165 NQVEFHPFLNQIHLLEYCKKHKIQLEAYSP 194 >UniRef50_A6NPD6 Cluster: Putative uncharacterized protein; n=3; Bacteria|Rep: Putative uncharacterized protein - Bacteroides capillosus ATCC 29799 Length = 287 Score = 121 bits (291), Expect = 6e-26 Identities = 72/172 (41%), Positives = 98/172 (56%) Frame = +1 Query: 136 LSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQEG 315 LSNG IP +G GT+K+ G+ + + +AI GYRH A YG E +G+A+ E Sbjct: 10 LSNGLSIPAVGFGTYKTGDGD-SAVLSNAIAQGYRHFDTASFYGTETALGQAVA----ES 64 Query: 316 VVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTD 495 + RED F+TSKLW T D A + +L L DYLDLYLIHWP+ E + Sbjct: 65 DIPREDFFLTSKLWKTEMGYDAALRAFDATLERLGTDYLDLYLIHWPRPDLELE------ 118 Query: 496 ADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKP 651 ++ +D +TW+ALE L GLVR++GVSNF L+ IL +A+V P Sbjct: 119 -----DWAKLDR-ETWRALERLYESGLVRAIGVSNFLPHHLEPILASANVAP 164 >UniRef50_Q7XY49 Cluster: Mannose 6-phosphate reductase; n=1; Griffithsia japonica|Rep: Mannose 6-phosphate reductase - Griffithsia japonica (Red alga) Length = 174 Score = 121 bits (291), Expect = 6e-26 Identities = 59/110 (53%), Positives = 71/110 (64%) Frame = +1 Query: 118 SVPVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIK 297 S TL +GAK+P+ G GTWK+ E QAV A+ GYRHI CA VY NE VG AI Sbjct: 2 STNTATLQSGAKMPLNGFGTWKASVEETEQAVTAALRAGYRHIDCAAVYWNEAAVGTAIS 61 Query: 298 TKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLI 447 I GVVKREDLFITSK+WNT H D V + SL++ +DY DL+L+ Sbjct: 62 KAISGGVVKREDLFITSKVWNTCHATDKVVDSCRQSLKDHQVDYFDLFLV 111 >UniRef50_Q4PDR0 Cluster: Putative uncharacterized protein; n=1; Ustilago maydis|Rep: Putative uncharacterized protein - Ustilago maydis (Smut fungus) Length = 339 Score = 121 bits (291), Expect = 6e-26 Identities = 72/190 (37%), Positives = 112/190 (58%), Gaps = 12/190 (6%) Frame = +1 Query: 118 SVPVTTLSNGAKIPVIGIGTWKSKPG-----EVTQAVKDAIDIGYRHIXCAFVYGNEKEV 282 ++P TL+ GAK+P +G+G W+ +PG E+ A+ AI +GYRH+ A Y NE EV Sbjct: 4 NIPSFTLNTGAKLPSVGMGCWQGQPGPGRDNELVDALVRAIKVGYRHLDTATGYRNEAEV 63 Query: 283 GEAIKTKIQEGVVKREDLFITSKLW-NTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQ 459 G+A++ Q GV R ++F+T+KL H D+V+ LE SL L IDY+DL+L+HWPQ Sbjct: 64 GQAVR---QSGVA-RSEIFVTTKLRPGGVH--DVVQ-ELENSLNELGIDYIDLWLLHWPQ 116 Query: 460 AYKEDDAIFPTDADGKIQFS---DVDYVDTWKALEPLVCH---GLVRSLGVSNFNSKQLQ 621 + +DD F T ++ + +TW +E + + G V+++GVSNF+ K L+ Sbjct: 117 GFTKDDGGFGTGESFGLEHQKHLGPTFNETWAKMEDVFLNSHKGKVKAIGVSNFSIKNLE 176 Query: 622 RILDNASVKP 651 + + V P Sbjct: 177 ILAKTSKVTP 186 Score = 40.3 bits (90), Expect = 0.14 Identities = 15/32 (46%), Positives = 21/32 (65%) Frame = +2 Query: 659 NQVECHPYLNXKRLKQFCEDRDIMITXYSPXG 754 NQ+E HPYL L ++C+ + I +T YSP G Sbjct: 189 NQIEAHPYLPEHELVKYCKHKSIHVTAYSPLG 220 >UniRef50_Q6NII7 Cluster: Putative oxidoreductase; n=2; Corynebacterium|Rep: Putative oxidoreductase - Corynebacterium diphtheriae Length = 290 Score = 120 bits (289), Expect = 1e-25 Identities = 63/177 (35%), Positives = 101/177 (57%) Frame = +1 Query: 121 VPVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKT 300 +P TL++G ++P IG GT+K + + +AV+ AI++GYRHI A +Y NE+EVG A+ Sbjct: 11 IPTITLNDGTEMPAIGFGTYKLREQDAYRAVRSAIEVGYRHIDTASLYKNEEEVGRAVAD 70 Query: 301 KIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDA 480 I G V R++LFIT+K+WN H L + + + SL L +DY+D ++HWP K Sbjct: 71 AITAGEVARDELFITTKVWNDMHGDQLTQRSFQESLHRLGLDYIDCCMVHWPWPQK---- 126 Query: 481 IFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKP 651 G YV+++ AL + G ++S+ V+NF + L+ I+ + P Sbjct: 127 -------GL-------YVESFAALAKIQGLGQLQSVAVANFYPEVLREIVAETGIAP 169 >UniRef50_A0JRJ3 Cluster: 2,5-didehydrogluconate reductase; n=3; Actinobacteria (class)|Rep: 2,5-didehydrogluconate reductase - Arthrobacter sp. (strain FB24) Length = 276 Score = 120 bits (289), Expect = 1e-25 Identities = 70/180 (38%), Positives = 96/180 (53%) Frame = +1 Query: 112 MTSVPVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEA 291 M PV L++G +IP IG+GTW +V AV +A++ GYRHI A YGNEK VG Sbjct: 1 MALSPVIELNDGHRIPQIGLGTWPLDDHQVAAAVVNAVEGGYRHIDTAVKYGNEKGVGNG 60 Query: 292 IKTKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKE 471 I++ + R +LFIT+KL F D L+ SL+ L +DY+DL LIHWP ++ Sbjct: 61 IRS----SGLDRSELFITTKLDGEFQGQDRAVAGLDGSLKRLGLDYVDLLLIHWPLPRRD 116 Query: 472 DDAIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKP 651 +++ TWK E L G VRS+GVSNF L+R++ V P Sbjct: 117 ------------------EFISTWKTFERLQADGKVRSIGVSNFKPAHLERLMAACDVVP 158 >UniRef50_A7CUW0 Cluster: 2,5-didehydrogluconate reductase; n=6; Bacteria|Rep: 2,5-didehydrogluconate reductase - Opitutaceae bacterium TAV2 Length = 334 Score = 120 bits (288), Expect = 1e-25 Identities = 83/248 (33%), Positives = 118/248 (47%) Frame = +1 Query: 112 MTSVPVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEA 291 M +P LS+G IP +G+G W+ ++ A + GYR I A +YGNE+ VG A Sbjct: 56 MRMIPTLPLSDGTSIPQLGLGVWQMPDDGAGVPIQAAFNAGYRAIDTAPIYGNEEGVGRA 115 Query: 292 IKTKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKE 471 I+ + R++L+IT+K+WN+ D A+ SL L ++Y+DLYLIHWP Sbjct: 116 IRAS----GLPRKELYITTKVWNSAQGYDSTLRAVRESLGRLQLEYVDLYLIHWPVP--- 168 Query: 472 DDAIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKP 651 KI YVDTWKAL + GL RS+GVSNF LQR+ D + P Sbjct: 169 -----------KID----RYVDTWKALAKIKADGLARSIGVSNFTPVYLQRLFDETGIVP 213 Query: 652 GH*PGRMPSVFKPXAIEAVLRRP*YYDNGVLPRWGXPDRPWAKPGDPHLMEDPKLKEIAD 831 V + L++ + + W+ G L+ DP L IA Sbjct: 214 ---------VVNQVELHPRLQQ--HELRAFHAKHRIVTEAWSPLGQGTLLADPVLAGIAQ 262 Query: 832 RLGKXAAQ 855 + G+ AAQ Sbjct: 263 KHGRSAAQ 270 >UniRef50_Q11BF8 Cluster: Aldo/keto reductase; n=12; Bacteria|Rep: Aldo/keto reductase - Mesorhizobium sp. (strain BNC1) Length = 308 Score = 119 bits (287), Expect = 2e-25 Identities = 79/240 (32%), Positives = 131/240 (54%), Gaps = 2/240 (0%) Frame = +1 Query: 142 NGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQEGVV 321 +G ++P+IG+G +++ P E T AV++A+ +GYRHI A YGNE+EVGE I+ + G+ Sbjct: 25 SGVEMPMIGLGVFQTPPDETTAAVEEALRLGYRHIDTAAAYGNEREVGEGIR---RAGIA 81 Query: 322 KREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTDAD 501 R+++FI +K+W + + D A + S L +D +DL L+H P P+ D Sbjct: 82 -RDEVFIETKIWISDYGYDETLHAFDKSAGKLGVDQIDLLLLHQP---------LPSAFD 131 Query: 502 GKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPGH*PGRMPSV 681 + ++ALE L+ G VR++GVSNF + L R+L S+ P + Sbjct: 132 RTL--------GAYRALEKLLADGKVRAIGVSNFMPEHLTRLLTETSIVPAVNQIEVHPY 183 Query: 682 FKPXAIEAVLRRP*YYDNGVLPRWGXP--DRPWAKPGDPHLMEDPKLKEIADRLGKXAAQ 855 F+ A++ + + ++G+L + P + + G+ +EDP L EIA + GK AAQ Sbjct: 184 FQQRALQRL-----HAEHGILTQAWSPIGGITFYRGGEKSTLEDPVLLEIAQQHGKSAAQ 238 >UniRef50_A6LZ55 Cluster: 2,5-didehydrogluconate reductase; n=1; Clostridium beijerinckii NCIMB 8052|Rep: 2,5-didehydrogluconate reductase - Clostridium beijerinckii NCIMB 8052 Length = 289 Score = 119 bits (287), Expect = 2e-25 Identities = 64/171 (37%), Positives = 99/171 (57%), Gaps = 1/171 (0%) Frame = +1 Query: 142 NGAKIPVIGIGTWKSKPGEVTQ-AVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQEGV 318 NG KIP +G G +K GE + AV +AI IGYRH A +YGNEK++G AI ++ Sbjct: 12 NGIKIPQVGFGVYKLNKGEDFETAVGEAIKIGYRHFDTAKIYGNEKDLGLAI----EKSQ 67 Query: 319 VKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTDA 498 + RE+ FITSK+WNT H + + A E + + LN++YLD+YLIH+ +Y Sbjct: 68 IPREEFFITSKVWNTDHGYEATKKAFEQTCKKLNVEYLDMYLIHFASSY----------- 116 Query: 499 DGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKP 651 Y++TW A+E L G ++ +GV+NF + L+ ++ ++ + P Sbjct: 117 ----------YLETWHAMEELYLQGKIKVIGVANFQIQHLEELMKHSRITP 157 >UniRef50_UPI00015B5BD7 Cluster: PREDICTED: similar to aldo-keto reductase; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to aldo-keto reductase - Nasonia vitripennis Length = 310 Score = 119 bits (286), Expect = 2e-25 Identities = 74/176 (42%), Positives = 109/176 (61%), Gaps = 4/176 (2%) Frame = +1 Query: 136 LSNGAKIPVIGIGTWKSKPGEVTQAVKD-AIDIGYRHIXCAFVYGNEKEVGEAIKTKIQE 312 L+NG +P++GIGT+K + EV + V D + +G+R I A VY NE+++G A+K + + Sbjct: 28 LNNGYDMPLVGIGTYKVRGREVIKRVIDESFAVGFRSIDTAVVYRNEEDIGLALKELLPK 87 Query: 313 GVVKREDLFITSKLWNTFH-RPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFP 489 +KRED+FITSKL + + PD +R ++E SL+ L+ YLDLYLIHWP A + I Sbjct: 88 YNLKREDIFITSKLSPSDNGDPDKIRKSVEDSLKALDTSYLDLYLIHWPGASR----ILE 143 Query: 490 TDADG-KIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNAS-VKP 651 D K++ V TW L L GL+RS+GVSN+ L+ +L++ S VKP Sbjct: 144 NSPDNPKLR------VTTWATLVELQQKGLLRSIGVSNYTVGHLEHLLEHCSGVKP 193 Score = 35.9 bits (79), Expect = 3.0 Identities = 15/36 (41%), Positives = 19/36 (52%) Frame = +2 Query: 659 NQVECHPYLNXKRLKQFCEDRDIMITXYSPXGXLPT 766 NQVECHP+ L +FC + I + YS G T Sbjct: 196 NQVECHPHFRQDELIEFCTKQGIHVQAYSSLGTSDT 231 >UniRef50_Q68ST9 Cluster: Reductase AKOR2; n=2; Pleurotus djamor|Rep: Reductase AKOR2 - Pleurotus djamor Length = 306 Score = 119 bits (286), Expect = 2e-25 Identities = 70/187 (37%), Positives = 106/187 (56%), Gaps = 7/187 (3%) Frame = +1 Query: 112 MTSVPVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKD----AIDIGYRHIXCAFVYGNEKE 279 M++ P L+ GA++P + +G W E K+ A+ GYRHI A +Y EK Sbjct: 1 MSAYPPIVLNTGARMPALALGGWAGLTEEERTQAKEWFLTALKSGYRHIDTAQIYYTEKS 60 Query: 280 VGEAIKTKIQEGVVKREDLFITSKL-WNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWP 456 VG AI+ E + RE+LFIT+KL WN R V + + SL NL +Y+DLYL+H+P Sbjct: 61 VGNAIR----ESGIPREELFITTKLPWNHHSR---VAESFQKSLENLGTEYIDLYLVHFP 113 Query: 457 Q-AYKEDDAIFPTDADGKIQFSDVDYV-DTWKALEPLVCHGLVRSLGVSNFNSKQLQRIL 630 Q + ++ FP + DG I+ + + D W +E L+ G V+++GVSN++ K L+ +L Sbjct: 114 QRVFYDETTDFPRNPDGSIKVVNSPTLNDVWADVETLLDTGKVKAIGVSNYSIKTLEELL 173 Query: 631 DNASVKP 651 A V P Sbjct: 174 KTAKVVP 180 Score = 39.9 bits (89), Expect = 0.18 Identities = 17/40 (42%), Positives = 26/40 (65%), Gaps = 2/40 (5%) Frame = +2 Query: 659 NQVECHPYLNXKRLKQFCEDRDIMITXYSPXG--XLPTDP 772 NQVE HP+L +L +C+++ I +T Y+P G + TDP Sbjct: 183 NQVELHPFLAQSKLLAYCKEKGIAVTAYTPTGYQTVLTDP 222 >UniRef50_P06632 Cluster: 2,5-diketo-D-gluconic acid reductase A; n=8; Actinomycetales|Rep: 2,5-diketo-D-gluconic acid reductase A - Corynebacterium sp. (strain ATCC 31090) Length = 278 Score = 119 bits (286), Expect = 2e-25 Identities = 72/178 (40%), Positives = 99/178 (55%) Frame = +1 Query: 118 SVPVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIK 297 +VP L++G IP +G G +K P + +AV++A+++GYRHI A +YGNE+ VG AI Sbjct: 2 TVPSIVLNDGNSIPQLGYGVFKVPPADTQRAVEEALEVGYRHIDTAAIYGNEEGVGAAIA 61 Query: 298 TKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDD 477 G+ R+DLFIT+KLWN H D A+ SL L +D +DLYL+HWP Sbjct: 62 A---SGIA-RDDLFITTKLWNDRHDGDEPAAAIAESLAKLALDQVDLYLVHWPT------ 111 Query: 478 AIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKP 651 P AD +YV W+ + L GL RS+GVSN L+RI+ V P Sbjct: 112 ---PA-AD--------NYVHAWEKMIELRAAGLTRSIGVSNHLVPHLERIVAATGVVP 157 >UniRef50_Q83N50 Cluster: 2,5-diketo-D-gluconic acid reductase; n=2; Tropheryma whipplei|Rep: 2,5-diketo-D-gluconic acid reductase - Tropheryma whipplei (strain Twist) (Whipple's bacillus) Length = 283 Score = 118 bits (285), Expect = 3e-25 Identities = 69/173 (39%), Positives = 101/173 (58%) Frame = +1 Query: 109 IMTSVPVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGE 288 ++T VP L +G IP G+GT++ P E + V+ AI++GYRHI A +Y NE+EVG Sbjct: 5 VLTYVPSVLLGDGVSIPQFGLGTYELPPNEASSVVQSAIELGYRHIDTASLYANEREVGR 64 Query: 289 AIKTKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYK 468 AI + +KRE+ F+T+KLWN+ +P R A E SL L++DY+DLYLIHWP Sbjct: 65 AIAS----SGIKREEFFVTTKLWNS-DQPK-PREAFERSLDLLSLDYVDLYLIHWPCP-- 116 Query: 469 EDDAIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRI 627 P++ Y++ W+ L L G +S+GVSNF S+ + +I Sbjct: 117 ------PSEL----------YINVWEVLLELKESGRAKSVGVSNFLSEHIDKI 153 >UniRef50_A7BA05 Cluster: Putative uncharacterized protein; n=1; Actinomyces odontolyticus ATCC 17982|Rep: Putative uncharacterized protein - Actinomyces odontolyticus ATCC 17982 Length = 292 Score = 118 bits (284), Expect = 4e-25 Identities = 68/177 (38%), Positives = 98/177 (55%) Frame = +1 Query: 121 VPVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKT 300 +P L G+ IPV+G GT+K P + AV A+++GYRHI A +YGNE EVG A++ Sbjct: 16 IPTFMLPTGSPIPVLGFGTYKVAPEDTYDAVSRALEVGYRHIDTAQMYGNEAEVGAALEA 75 Query: 301 KIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDA 480 G+ REDLFIT+K+ N+ H PD ++ SL +L DY+DL L+HWP Sbjct: 76 ---SGIA-REDLFITTKVDNSNHEPDRAAASIRRSLEDLRTDYVDLLLVHWP-------- 123 Query: 481 IFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKP 651 PT G D W ALE G R++G+SN+ + ++ + + A+V P Sbjct: 124 -LPTLYGG-------DVALPWPALEDAFNAGGARAIGLSNYEREHVEAVREVATVAP 172 >UniRef50_Q838E0 Cluster: Oxidoreductase, aldo/keto reductase family; n=24; Bacilli|Rep: Oxidoreductase, aldo/keto reductase family - Enterococcus faecalis (Streptococcus faecalis) Length = 279 Score = 117 bits (282), Expect = 7e-25 Identities = 71/184 (38%), Positives = 95/184 (51%), Gaps = 2/184 (1%) Frame = +1 Query: 106 LIMTSVPVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVG 285 +I + TL+NG KIP +G+G ++ E + V++ I GYR I A +YGNE G Sbjct: 1 MITSLADTVTLNNGTKIPGMGLGVFQIPDEETAKVVEEGIINGYRLIDTAQIYGNESGTG 60 Query: 286 EAIKTKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWP--Q 459 IK + + REDLF+TSK+WN D A SL L +DYLDLYLIHWP Sbjct: 61 AGIKAGLAATGLNREDLFVTSKVWNAHISYDETIQAFNDSLERLGLDYLDLYLIHWPGNN 120 Query: 460 AYKEDDAIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNA 639 +YKE +W+ALE L G V+++GVSNF L+ +L A Sbjct: 121 SYKE----------------------SWQALETLYAEGKVKAIGVSNFQVHHLEDLLSYA 158 Query: 640 SVKP 651 V P Sbjct: 159 KVVP 162 Score = 39.9 bits (89), Expect = 0.18 Identities = 16/32 (50%), Positives = 21/32 (65%) Frame = +2 Query: 653 VTNQVECHPYLNXKRLKQFCEDRDIMITXYSP 748 V NQVE HP L+ K ++ FCE DI + +SP Sbjct: 163 VINQVELHPKLDQKEVRDFCEKHDIKVQAWSP 194 >UniRef50_Q9ZUJ6 Cluster: T2K10.1 protein; n=16; core eudicotyledons|Rep: T2K10.1 protein - Arabidopsis thaliana (Mouse-ear cress) Length = 176 Score = 117 bits (282), Expect = 7e-25 Identities = 66/177 (37%), Positives = 100/177 (56%), Gaps = 8/177 (4%) Frame = +1 Query: 112 MTSVPVTTLSNGAK----IPVIGIGTWKS---KPGEVTQAVKDAIDIGYRHIXCAFVYGN 270 +T+VP + +G +PV+G GT S +P + + V +AI +GYRH + Y Sbjct: 3 LTTVPTLAIRSGPSGHHSMPVLGFGTAASPLPEPTMLKETVIEAIKLGYRHFDTSPRYQT 62 Query: 271 EKEVGEAIKTKIQEGVVK-REDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLI 447 E+ +GEA+ + G+V+ R + F+T+KLW LV A++ SL+NL +DYLDLY+I Sbjct: 63 EEPIGEALAEAVSLGLVRSRSEFFVTTKLWCADAHGGLVVPAIKRSLKNLKLDYLDLYII 122 Query: 448 HWPQAYKEDDAIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQL 618 HWP + K FP D D F +D+ W +E GL + +GVSNF+ K+L Sbjct: 123 HWPVSSKPGKYKFPIDED---DFMPMDFEVVWSEMEECQRLGLAKCIGVSNFSCKKL 176 >UniRef50_A7P424 Cluster: Chromosome chr1 scaffold_5, whole genome shotgun sequence; n=1; Vitis vinifera|Rep: Chromosome chr1 scaffold_5, whole genome shotgun sequence - Vitis vinifera (Grape) Length = 247 Score = 117 bits (282), Expect = 7e-25 Identities = 91/264 (34%), Positives = 132/264 (50%), Gaps = 16/264 (6%) Frame = +1 Query: 112 MTSVPVTTL-SNGAKIPVIGIGT--WKSKPGE-VTQAVKDAIDIGYRHIXCAFVYGNEKE 279 M S+P TL S G IP++G+ T + P E + ++ AI++GYRH C Y +EK Sbjct: 1 MISIPEMTLGSTGKAIPLVGMVTTVYPFAPSETMIDSILTAIELGYRHFDCVAAYLSEKP 60 Query: 280 VGEAIKTKIQEGVVK-REDLFITSKLWNTFHRPDLVRGALEVSLR---------NLNIDY 429 +GEAIK ++ G++K R++LFITSKLW + D V AL+ +L+ NL +DY Sbjct: 61 LGEAIKKAVKLGLIKSRDELFITSKLWCSDAHHDRVLPALQNTLKISSILSFSKNLQLDY 120 Query: 430 LDLYLIHWPQAYKEDDAIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNS 609 LDLYLIHW +DG + +D WKA+E L +++GVSNF+ Sbjct: 121 LDLYLIHW--------------SDGHLP---IDLGSVWKAMEDFQKLSLTKAIGVSNFSC 163 Query: 610 KQLQRILDNASVKP--GH*PGRMPSVFKPXAIEAVLRRP*YYDNGVLPRWGXPDRPWAKP 783 +L+ +L AS+ P P++ A + R + P W P W Sbjct: 164 NKLEELLQTASILPAVNQVSENEPTLAAEEAQGVIYVRKRVSISRHTPPW-VPKEHW--- 219 Query: 784 GDPHLMEDPKLKEIADRLGKXAAQ 855 G +ME LK+IA G AQ Sbjct: 220 GTDRVMECEVLKKIARETGNSIAQ 243 >UniRef50_A3C1Z7 Cluster: Putative uncharacterized protein; n=2; Oryza sativa (japonica cultivar-group)|Rep: Putative uncharacterized protein - Oryza sativa subsp. japonica (Rice) Length = 288 Score = 117 bits (282), Expect = 7e-25 Identities = 80/253 (31%), Positives = 124/253 (49%), Gaps = 8/253 (3%) Frame = +1 Query: 121 VPVTTLSNGAKIPVIGIGTWK-----SKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVG 285 +P LS+G +P +G+GT + P V V AI+ GYRH A VY E +G Sbjct: 1 MPEAALSSGKPMPRVGMGTASFPLGATDPSTVKDVVLRAIEAGYRHFDTAAVYQTEAILG 60 Query: 286 EAIKTKIQEGVV-KREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQA 462 +A+ ++ G+V R++L+ITSKLW P V +L +LR + ++YLDLYLIH+P + Sbjct: 61 DAVAEAVRAGLVASRDELYITSKLWVAHAHPGHVLPSLRRALRKMQMEYLDLYLIHFPVS 120 Query: 463 YK--EDDAIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDN 636 + ED D + +D WK +E GL +++GVSNF+ K+L+ +L Sbjct: 121 MRLAEDPESMTYSKDDLVM---MDMEGVWKEMEECQRLGLTKAIGVSNFSCKKLETLLSF 177 Query: 637 ASVKPGH*PGRMPSVFKPXAIEAVLRRP*YYDNGVLPRWGXPDRPWAKPGDPHLMEDPKL 816 A++ P + + + + P G PW+ +M+ P L Sbjct: 178 ATISPAANQVEVHPYCRQNKLREFCKEKGIQLCAYSP-LGGKGTPWSNNA---VMDCPLL 233 Query: 817 KEIADRLGKXAAQ 855 K+IA GK AQ Sbjct: 234 KQIAMERGKTIAQ 246 >UniRef50_Q5HR31 Cluster: Oxidoreductase, aldo/keto reductase family; n=3; Staphylococcus|Rep: Oxidoreductase, aldo/keto reductase family - Staphylococcus epidermidis (strain ATCC 35984 / RP62A) Length = 279 Score = 117 bits (281), Expect = 1e-24 Identities = 64/175 (36%), Positives = 98/175 (56%) Frame = +1 Query: 127 VTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKI 306 V L+NG +P +G+G +K ++ + V+ A+D GYR A+ YGNEK +G A+K Sbjct: 5 VQILNNGYPMPAVGLGVYKIADEQMEEVVRTALDAGYRAFDTAYFYGNEKALGSALK--- 61 Query: 307 QEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIF 486 V+R++LFITSKLWN + D SL NL +DYLDL+LIHWP E+D + Sbjct: 62 -HSNVERDELFITSKLWNDYQGYDQTIEYFNKSLDNLGLDYLDLFLIHWP---CENDQL- 116 Query: 487 PTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKP 651 Y++++KALE L G ++++GV NF L++++ + P Sbjct: 117 --------------YIESYKALEHLYEEGKIKAIGVCNFKIHHLEKLMKETKITP 157 Score = 39.9 bits (89), Expect = 0.18 Identities = 13/30 (43%), Positives = 21/30 (70%) Frame = +2 Query: 659 NQVECHPYLNXKRLKQFCEDRDIMITXYSP 748 NQ+E HPY N + ++ FC++ DI +T + P Sbjct: 160 NQIELHPYFNQQDVQDFCDEHDIKVTAWMP 189 >UniRef50_Q1VRG6 Cluster: YvgN; n=1; Psychroflexus torquis ATCC 700755|Rep: YvgN - Psychroflexus torquis ATCC 700755 Length = 280 Score = 117 bits (281), Expect = 1e-24 Identities = 69/173 (39%), Positives = 103/173 (59%), Gaps = 1/173 (0%) Frame = +1 Query: 136 LSNGAKIPVIGIGTWKSKPGEVTQAV-KDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQE 312 L++G +IP++G GT+K+ E +++ K A+ +GYR I +Y NE+ VG+AIK + Sbjct: 5 LNDGNRIPIVGFGTYKANEEEGIKSIQKSALTLGYRLIDTVAIYQNEEAVGKAIKAR--- 61 Query: 313 GVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPT 492 GV+ RE++F+T+KLW R AL+ SLR L+++Y+DLYLIHWP +AI Sbjct: 62 GVL-REEIFVTTKLWRENLGYKQTRIALDESLRKLDLNYIDLYLIHWPA-----NAINYK 115 Query: 493 DADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKP 651 D DTW+A+E L G ++SLGVSNF + L+ + A V P Sbjct: 116 D-------WQKTNADTWRAMEELQAEGKIKSLGVSNFWPEHLEALFQTAKVSP 161 >UniRef50_Q4P4P1 Cluster: Putative uncharacterized protein; n=1; Ustilago maydis|Rep: Putative uncharacterized protein - Ustilago maydis (Smut fungus) Length = 322 Score = 117 bits (281), Expect = 1e-24 Identities = 66/173 (38%), Positives = 96/173 (55%), Gaps = 1/173 (0%) Frame = +1 Query: 136 LSNGAKIPVIGIGTWKS-KPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQE 312 L+NG +IP + +G +K+ G A K A D GYRHI A Y NE+ VG A+ +E Sbjct: 21 LNNGQEIPQVALGVYKAPNDGSTENACKWAFDAGYRHIDSAARYMNEESVGRALAEWTKE 80 Query: 313 GVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPT 492 V R ++FITSKLW+ H D A+E SL+ LN+DY+D+YL+H P + + Sbjct: 81 NNVPRSEIFITSKLWDADH--DKAAAAIEDSLKKLNVDYMDMYLMHSPGTMGAEKRL--- 135 Query: 493 DADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKP 651 + WKALE V G ++++GVSNF+ ++L +L N +KP Sbjct: 136 --------------EAWKALEEAVDAGKIKTIGVSNFDVEELDHLLANCRIKP 174 >UniRef50_A7ALH6 Cluster: Putative uncharacterized protein; n=1; Parabacteroides merdae ATCC 43184|Rep: Putative uncharacterized protein - Parabacteroides merdae ATCC 43184 Length = 301 Score = 116 bits (278), Expect = 2e-24 Identities = 91/250 (36%), Positives = 125/250 (50%), Gaps = 2/250 (0%) Frame = +1 Query: 112 MTSVPVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEA 291 M VP L+NG ++P +G+GT+ K + V AI +G+R I A YGNEKEVGE Sbjct: 26 MNKVPTVKLNNGMEMPQLGVGTFLVKDN-AAERVCHAIKVGFRLIDTAQGYGNEKEVGEG 84 Query: 292 IKTKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKE 471 I + G+ +RE LFIT+K+ R VR +L+ SL +L DY+DL LIHWP Sbjct: 85 I---CRSGIDRRE-LFITTKVNTMEMRGGTVRQSLDKSLADLGTDYIDLVLIHWP----- 135 Query: 472 DDAIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKP 651 G I+ +TW+ LE V G +RS+GVSNFN L +L+ A ++P Sbjct: 136 --------VKGHIK-------ETWQILEEYVDKGKIRSIGVSNFNPHHLDELLEYARIRP 180 Query: 652 GH*PGRMPSVFKPXAIEAVLRRP*YYDNGVLPRWGXPDRPWAKPGD--PHLMEDPKLKEI 825 V IE + + + G R G W G +++DP + EI Sbjct: 181 ---------VVNQIEIEPYMTQ--HDVVGYTFRKGIQVEAWGPLGQGVTGVLDDPAIGEI 229 Query: 826 ADRLGKXAAQ 855 A R GK AAQ Sbjct: 230 AARHGKSAAQ 239 >UniRef50_A5PDA8 Cluster: Putative oxidoreductase protein; n=1; Erythrobacter sp. SD-21|Rep: Putative oxidoreductase protein - Erythrobacter sp. SD-21 Length = 272 Score = 114 bits (275), Expect = 5e-24 Identities = 68/180 (37%), Positives = 94/180 (52%) Frame = +1 Query: 112 MTSVPVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEA 291 MT P L++G +IP +G GTW+ + + QAV AID+GY I A +YGNEK VG Sbjct: 1 MTDYPTLNLNDGRQIPQLGFGTWQMEEEDAPQAVSTAIDVGYWLIDTAAIYGNEKGVG-- 58 Query: 292 IKTKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKE 471 +GV + D+F+ +K+WN D A E L L +++D+ LIHWP K+ Sbjct: 59 ------KGVGEWSDIFLQTKIWNDSQGYDRTLRAAEKCLERLGREHVDMLLIHWPCPEKD 112 Query: 472 DDAIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKP 651 +VDTWKAL L G +S+GVSNF + L+RI+D V P Sbjct: 113 ------------------QFVDTWKALIELRDAGKAKSIGVSNFREEDLKRIIDETGVTP 154 >UniRef50_A2UAH0 Cluster: Aldo/keto reductase; n=1; Bacillus coagulans 36D1|Rep: Aldo/keto reductase - Bacillus coagulans 36D1 Length = 273 Score = 114 bits (274), Expect = 7e-24 Identities = 66/182 (36%), Positives = 100/182 (54%), Gaps = 2/182 (1%) Frame = +1 Query: 112 MTSVPVT-TLSNGAKIPVIGIGTWKSKPGEVT-QAVKDAIDIGYRHIXCAFVYGNEKEVG 285 M+S+ T L NG IP IG+GTW+ GE T AV A+ GYRHI A+ Y NE+ VG Sbjct: 1 MSSLHETFVLENGVAIPKIGLGTWQVPNGETTYHAVSFALKNGYRHIDTAYAYHNEESVG 60 Query: 286 EAIKTKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAY 465 +A++ + + R D+F+TSKL D + ++ N ++ LDLYLIH P + Sbjct: 61 KAVR----DSGIDRRDIFVTSKLPAEIKSYDKALKTFDETMGNFGLEQLDLYLIHAPWPW 116 Query: 466 KEDDAIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASV 645 E A + + ++ WKA+E + G R++GVSNF+ L+ +++NA + Sbjct: 117 SEKGADYTKEN-----------IEVWKAMEEIYESGRCRAIGVSNFSVSDLKAVMENAKI 165 Query: 646 KP 651 KP Sbjct: 166 KP 167 >UniRef50_Q4PHK0 Cluster: Putative uncharacterized protein; n=1; Ustilago maydis|Rep: Putative uncharacterized protein - Ustilago maydis (Smut fungus) Length = 355 Score = 113 bits (272), Expect = 1e-23 Identities = 73/201 (36%), Positives = 105/201 (52%), Gaps = 29/201 (14%) Frame = +1 Query: 136 LSNGAKIPVIGIGTWKSKPGEVTQAVKDAID-----------------IGYRHIX----- 249 L+ GA+IPVIG+GTW+S PGEV +AV+ AI +GY + Sbjct: 16 LNTGAEIPVIGLGTWQSAPGEVAKAVESAIKAGYRHIVSMLTSLLTLTLGYVALHPLYIP 75 Query: 250 -----CAFVYGNEKEVGEAIKTKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRN 414 A++YGNE EVG+ IK V R +LF+T+K+W T+HR L+ SL+ Sbjct: 76 FLAKDAAWIYGNENEVGQGIKAS----GVPRSELFVTTKIWCTYHRQP--EACLDESLQR 129 Query: 415 LNIDYLDLYLIHWP-QAYKEDDAIFPTDADGKIQFS-DVDYVDTWKALEPLVCHGLVRSL 588 L +DY+DL L+HWP K D P + DG D TW+ +E L G +++ Sbjct: 130 LGLDYVDLLLVHWPVPLVKRGDEKIPLNEDGSRAIDRDWSPEQTWELMEKLPATGKTKAI 189 Query: 589 GVSNFNSKQLQRILDNASVKP 651 GVSN++ L ++L A + P Sbjct: 190 GVSNWSIAFLDKLLAKAKIVP 210 Score = 37.5 bits (83), Expect = 0.97 Identities = 15/32 (46%), Positives = 20/32 (62%) Frame = +2 Query: 659 NQVECHPYLNXKRLKQFCEDRDIMITXYSPXG 754 NQVE HP+L L ++C D+ I+ YSP G Sbjct: 213 NQVELHPFLPQHELVKYCHDKGILPQAYSPLG 244 >UniRef50_Q28P63 Cluster: Aldo/keto reductase; n=4; Rhodobacteraceae|Rep: Aldo/keto reductase - Jannaschia sp. (strain CCS1) Length = 276 Score = 112 bits (270), Expect = 2e-23 Identities = 62/180 (34%), Positives = 98/180 (54%) Frame = +1 Query: 112 MTSVPVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEA 291 MT PV +GA+IP +G G W+ + V+ AI+IGYR I A++Y NE +GE Sbjct: 1 MTDRPVIKFHDGAQIPQVGFGIWQVPQDIAGETVRSAIEIGYRMIDGAYLYMNEAGLGEG 60 Query: 292 IKTKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKE 471 ++ + R+++F+T+K+WN R ++E SL+ + ++ LDL LIHWP Sbjct: 61 LRA----SGLPRDEVFVTTKVWNNEQGAAKARASVERSLKTIGVEQLDLVLIHWP----- 111 Query: 472 DDAIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKP 651 + D+ Y++TWKA + + GL+RS+G SNFN+ L+RI+ P Sbjct: 112 ------------VPSQDL-YLETWKAFQDMRDEGLMRSIGTSNFNADHLERIIAETGEAP 158 >UniRef50_Q17DN1 Cluster: Aldo-keto reductase; n=1; Aedes aegypti|Rep: Aldo-keto reductase - Aedes aegypti (Yellowfever mosquito) Length = 284 Score = 112 bits (270), Expect = 2e-23 Identities = 55/108 (50%), Positives = 77/108 (71%), Gaps = 2/108 (1%) Frame = +1 Query: 124 PVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTK 303 P+ L+NG ++PV+G+GTW SK GE +A+K AID GYRHI A+ Y NEKEVGEAI+ K Sbjct: 6 PMVKLNNGLEMPVLGLGTWLSKEGEGVEAIKAAIDAGYRHIDTAYFYQNEKEVGEAIRAK 65 Query: 304 IQEGVVKREDLFITSKL--WNTFHRPDLVRGALEVSLRNLNIDYLDLY 441 I+EGVV REDLF+T+K W+T +L+ + L+ ++DY+D + Sbjct: 66 IEEGVVCREDLFVTTKFIDWDT---KNLMPYDADGKLQFSDVDYIDTW 110 Score = 83.4 bits (197), Expect = 1e-14 Identities = 35/57 (61%), Positives = 46/57 (80%) Frame = +1 Query: 481 IFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKP 651 + P DADGK+QFSDVDY+DTWKA+E L+ G V+S+GVSNFNS+Q+ R+L +KP Sbjct: 90 LMPYDADGKLQFSDVDYIDTWKAMEKLLKTGKVKSIGVSNFNSEQITRLLAECEIKP 146 Score = 50.4 bits (115), Expect = 1e-04 Identities = 20/34 (58%), Positives = 27/34 (79%) Frame = +2 Query: 653 VTNQVECHPYLNXKRLKQFCEDRDIMITXYSPXG 754 VTNQVEC+P LN ++L +FC++ DI +T YSP G Sbjct: 147 VTNQVECNPSLNQRKLTEFCKNLDITLTAYSPLG 180 >UniRef50_Q5FT75 Cluster: Putative 2,5-diketo-D-gluconic acid reductase; n=1; Gluconobacter oxydans|Rep: Putative 2,5-diketo-D-gluconic acid reductase - Gluconobacter oxydans (Gluconobacter suboxydans) Length = 279 Score = 112 bits (269), Expect = 3e-23 Identities = 68/175 (38%), Positives = 94/175 (53%) Frame = +1 Query: 127 VTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKI 306 V + +G +P IG+G W++ P E + VK+A+ +GYR + A +Y NE+ VG+ Sbjct: 13 VISFHDGHTMPQIGLGVWETPPDETAEVVKEAVKLGYRSVDTARLYKNEEGVGK------ 66 Query: 307 QEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIF 486 G+ ++F+T+KLWN D A E S R L LDLYLIHWP Sbjct: 67 --GLEDHPEIFLTTKLWNDEQGYDSTLRAYEESARLLRRPVLDLYLIHWPMP-------- 116 Query: 487 PTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKP 651 A G+ YV+TWKAL L G V+S+GVSNF S+ L+RI+D V P Sbjct: 117 ---AQGQ-------YVETWKALVELKKSGRVKSIGVSNFESEHLERIMDATGVVP 161 >UniRef50_Q5FLI5 Cluster: Aldehyde reductase; n=2; Bacteria|Rep: Aldehyde reductase - Lactobacillus acidophilus Length = 278 Score = 112 bits (269), Expect = 3e-23 Identities = 81/244 (33%), Positives = 122/244 (50%), Gaps = 3/244 (1%) Frame = +1 Query: 133 TLSNGAKIPVIGIGTWKSKP-GEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQ 309 TL+NG K+P +G G ++ + Q V+D +++GYR + A +YGNE+ VG+AIK Sbjct: 6 TLNNGIKMPRLGFGVYQIDDLAQAQQVVEDGLEVGYRLVDTAQIYGNEQAVGDAIK---- 61 Query: 310 EGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFP 489 V RED+FITSK+W + D A + S++ L +DY+DLYLIH P Y Sbjct: 62 HSNVPREDIFITSKIWVDDYGYDNTLKAFDDSMKKLQLDYIDLYLIHKP--YN------- 112 Query: 490 TDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPGH*PGR 669 DY TW+ALE L G +R++GVS+F +++L ++ VKP Sbjct: 113 ------------DYYGTWRALERLYQEGRIRAIGVSSFWNERLADLITFNDVKPA----- 155 Query: 670 MPSVFKPXAIEAVLRRP*YYDNGVLPRWGXPDRPWA--KPGDPHLMEDPKLKEIADRLGK 843 IE + + + + G WA G H+ +P L+EIA++ K Sbjct: 156 ------VNQIETNVWNQEWKSQQYMEKEGVQPEAWAPFAEGANHIFTNPLLEEIAEKHHK 209 Query: 844 XAAQ 855 AQ Sbjct: 210 TTAQ 213 >UniRef50_Q24C22 Cluster: Oxidoreductase, aldo/keto reductase family protein; n=4; Oligohymenophorea|Rep: Oxidoreductase, aldo/keto reductase family protein - Tetrahymena thermophila SB210 Length = 297 Score = 111 bits (267), Expect = 5e-23 Identities = 65/177 (36%), Positives = 93/177 (52%) Frame = +1 Query: 121 VPVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKT 300 VP+ G IP IG GT++ + + V +A+ IGY HI A VY NE+++ + I Sbjct: 13 VPILNFREGGSIPQIGYGTYELRQNDCIIGVTEALKIGYTHIDTASVYRNEQDIAKVIHN 72 Query: 301 KIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDA 480 +KREDLFITSK+ + + A++ L LNI YLD LIHWP K Sbjct: 73 PAYG--IKREDLFITSKISPGEQGYEQAKKAVQDMLTRLNIKYLDCVLIHWPGVSK---- 126 Query: 481 IFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKP 651 P + Q ++TWKAL L G+++ +GVSNFN LQ +++ + KP Sbjct: 127 -LPPNDPKNAQIR----LETWKALIELRKAGVIKHIGVSNFNINHLQHLIEKSEFKP 178 >UniRef50_Q7NB44 Cluster: ARA1; n=3; Firmicutes|Rep: ARA1 - Mycoplasma gallisepticum Length = 289 Score = 111 bits (266), Expect = 6e-23 Identities = 61/173 (35%), Positives = 99/173 (57%), Gaps = 1/173 (0%) Frame = +1 Query: 136 LSNGAKIPVIGIGTWKSKPGEVT-QAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQE 312 L+N K+P IG GT+K + G+ T +AVK A+++GYRH+ CA +Y N+ V + IK Sbjct: 16 LANNYKMPSIGFGTYKLEDGKQTVEAVKTALEVGYRHLDCAEIYENQLSVSQGIKLS--- 72 Query: 313 GVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPT 492 V R+++FITSK+WN + + A L++L+++YLDL LIHWP D Sbjct: 73 -GVNRKEIFITSKIWNDDKGYESTKKAFHKILKDLDLEYLDLLLIHWPIGKGFKD----- 126 Query: 493 DADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKP 651 + +V+ TWKA+E G ++++G+SNF ++ + +A + P Sbjct: 127 ------NWQEVN-AQTWKAMEEFYLEGKIKAIGLSNFLVHHIEALKKSAKILP 172 >UniRef50_Q03X85 Cluster: Aldo/keto reductase of diketogulonate reductase family; n=1; Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293|Rep: Aldo/keto reductase of diketogulonate reductase family - Leuconostoc mesenteroides subsp. mesenteroides (strain ATCC 8293 /NCDO 523) Length = 288 Score = 110 bits (265), Expect = 9e-23 Identities = 56/129 (43%), Positives = 78/129 (60%), Gaps = 2/129 (1%) Frame = +1 Query: 133 TLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQE 312 TL+NGA++P +G G ++ E QAV DAI+ GYR I A VYGNE E G+ + I Sbjct: 5 TLNNGAQMPQLGFGVFQIPAEETKQAVVDAINAGYRSIDTARVYGNEAETGQGVNEAIAN 64 Query: 313 GVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWP--QAYKEDDAIF 486 VV RE+LF+T+KLW + + +GA++ SL+ L DY DL L+H P Y A+ Sbjct: 65 AVVAREELFLTTKLWLSEFSYEAAKGAIDDSLKKLGTDYADLILLHQPYGDVYGAYKALA 124 Query: 487 PTDADGKIQ 513 ADGK++ Sbjct: 125 EAQADGKVK 133 >UniRef50_UPI00006CCCD7 Cluster: oxidoreductase, aldo/keto reductase family protein; n=1; Tetrahymena thermophila SB210|Rep: oxidoreductase, aldo/keto reductase family protein - Tetrahymena thermophila SB210 Length = 323 Score = 110 bits (264), Expect = 1e-22 Identities = 64/188 (34%), Positives = 102/188 (54%), Gaps = 6/188 (3%) Frame = +1 Query: 106 LIMTSVPVTTLSNGAKIPVIGIGTW------KSKPGEVTQAVKDAIDIGYRHIXCAFVYG 267 +I + L+NG K+P++G+GT + E+T + +A+D GYR+ A Y Sbjct: 7 IINQDIKYVQLNNGYKMPLLGLGTQPYDIVTRVTVEEMTTLLSNALDFGYRNFDTAKQYR 66 Query: 268 NEKEVGEAIKTKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLI 447 NE E+G+A + Q+G KRED+FIT+KL+ F ++ ++ SL L Y+DLYLI Sbjct: 67 NEVEIGQAFQNIFQQGKYKREDVFITTKLF-PFKIEKKIKEVVQNSLDQLQTSYIDLYLI 125 Query: 448 HWPQAYKEDDAIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRI 627 W T+ DG + + + W+ LE V G++RS+GV+NFN + + + Sbjct: 126 QW------SFTPVLTNFDGSVAVNHRPIHEVWRELEECVELGMIRSIGVANFNCQMVLDL 179 Query: 628 LDNASVKP 651 L A +KP Sbjct: 180 LSYAKIKP 187 >UniRef50_Q890A0 Cluster: Oxidoreductase; n=6; Lactobacillales|Rep: Oxidoreductase - Lactobacillus plantarum Length = 282 Score = 110 bits (264), Expect = 1e-22 Identities = 64/173 (36%), Positives = 96/173 (55%), Gaps = 1/173 (0%) Frame = +1 Query: 136 LSNGAKIPVIGIGTWKSKPGEVT-QAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQE 312 L+NG IP + GTW+ GE T QAV+ A+ GYRHI A Y NE VG+AI+ + Sbjct: 10 LANGVNIPKVAFGTWQIPGGEATYQAVRAALAAGYRHIDTALAYQNEASVGQAIR----D 65 Query: 313 GVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPT 492 + RE +F+T+KL + SL+NL +DY+DLYL+H P +P Sbjct: 66 SGIPREQIFVTTKLPAETKSYQGALNDFDRSLKNLGLDYVDLYLVHAP---------WPW 116 Query: 493 DADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKP 651 G++ D +D W+A+E + G +++GVSNF + L+ IL+ A++ P Sbjct: 117 GQVGRVY--DEANLDVWQAMEAIYQSGRAKAIGVSNFAVRDLKNILNQATIPP 167 >UniRef50_Q1RFP0 Cluster: 2,5-diketo-D-gluconic acid reductase A; n=21; Bacteria|Rep: 2,5-diketo-D-gluconic acid reductase A - Escherichia coli (strain UTI89 / UPEC) Length = 294 Score = 109 bits (262), Expect = 2e-22 Identities = 68/180 (37%), Positives = 95/180 (52%), Gaps = 2/180 (1%) Frame = +1 Query: 118 SVPVTTLSNGAKIPVIGIGTWKSKPGEVT-QAVKDAIDIGYRHIXCAFVYGNEKEVGEAI 294 +V + LSN K+P++G G ++ +V Q+V +AI GYR I A VYGNE VGEA+ Sbjct: 5 TVEFSVLSNNLKMPMMGFGVFQVTDKDVCKQSVLNAIRTGYRLIDTAAVYGNEDAVGEAV 64 Query: 295 KTKIQEGVVKREDLFITSKLW-NTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKE 471 + I EG+ RE+LFITSKLW D+ +E SL+ ++Y DLYL+H QA + Sbjct: 65 REAISEGLCTREELFITSKLWVQDMLNQDIAAAGIEASLKKSGLEYFDLYLLH--QAMR- 121 Query: 472 DDAIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKP 651 DY W+ALE G ++++GVSNF L + VKP Sbjct: 122 ------------------DYFSAWRALEDAYEEGKLKAIGVSNFYPHVLANFCETVRVKP 163 >UniRef50_Q5TNP1 Cluster: ENSANGP00000029046; n=2; Culicidae|Rep: ENSANGP00000029046 - Anopheles gambiae str. PEST Length = 331 Score = 109 bits (261), Expect = 3e-22 Identities = 67/168 (39%), Positives = 93/168 (55%), Gaps = 3/168 (1%) Frame = +1 Query: 136 LSNGAKIPVIGIGTWKSKPGEVTQAVKD-AIDIGYRHIXCAFVYGNEKEVGEAIKTKIQE 312 L+ G IP+ G GT++ E+ V D A++ GYRHI A VY NE+ +G A+KT + + Sbjct: 36 LNTGFDIPLAGFGTYQIHGQELIYQVLDYALEAGYRHIDTAVVYRNEEYIGTALKTLLPK 95 Query: 313 GVVKREDLFITSKLWNTFHRPD-LVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFP 489 +KRED+FITSKL + + + V + SL NL DYLDLYLIHWP + Sbjct: 96 YNLKREDIFITSKLISQSGKDEAFVEQMVRKSLANLQTDYLDLYLIHWPGVSGKCGRWKW 155 Query: 490 TDADGKIQFSDVDY-VDTWKALEPLVCHGLVRSLGVSNFNSKQLQRIL 630 +V Y +W AL L G +RS+GVSN+ K L+ +L Sbjct: 156 LFGMQVTHPDNVKYRAASWNALSKLEREGCLRSIGVSNYTVKHLKEML 203 >UniRef50_A0JRJ6 Cluster: Aldo/keto reductase; n=2; Micrococcineae|Rep: Aldo/keto reductase - Arthrobacter sp. (strain FB24) Length = 281 Score = 108 bits (260), Expect = 3e-22 Identities = 66/178 (37%), Positives = 94/178 (52%) Frame = +1 Query: 118 SVPVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIK 297 ++P TL+NG KIP +G G ++ P E + V+DA++ GYRHI A Y NE VG AI Sbjct: 8 TIPQLTLNNGVKIPQLGFGVFQVPPEETQRIVEDALEAGYRHIDTAAAYRNEAGVGAAIS 67 Query: 298 TKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDD 477 + RED+FIT+KL N A + S + L ++++DLYLIHW Sbjct: 68 A----SGIPREDIFITTKLRN--GEQGNAHEAFQNSRKALGVEFVDLYLIHW-------- 113 Query: 478 AIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKP 651 P + G Y + WKA+E L + +R++GVSNF + L +L A V P Sbjct: 114 ---PVPSQGL-------YTEAWKAMEKLYANSQIRAIGVSNFLGEHLDTLLPAADVVP 161 >UniRef50_A0AWM8 Cluster: Aldo/keto reductase; n=4; Actinomycetales|Rep: Aldo/keto reductase - Arthrobacter sp. (strain FB24) Length = 287 Score = 108 bits (259), Expect = 5e-22 Identities = 68/179 (37%), Positives = 93/179 (51%) Frame = +1 Query: 115 TSVPVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAI 294 + +P L +G IP +G+GTW E AV+ A+ GYR + AF Y NE+ VG I Sbjct: 11 SDIPRLKLPHGHTIPRLGLGTWPMLEDECETAVRFALQSGYRLVDTAFQYRNEEAVGRGI 70 Query: 295 KTKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKED 474 +T V R +LFI+SK H D V+ A + SLR L +D+LD+++ HWP Sbjct: 71 RT----AGVPRSELFISSKFNKESHSIDGVQRAYDESLRKLGLDHLDMFMCHWP------ 120 Query: 475 DAIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKP 651 A GK YVD WK L L+ G V+++GVSNF L+ I+D V P Sbjct: 121 -----VPALGK-------YVDAWKGLVKLLEEGRVKAIGVSNFKPAHLKDIIDATGVVP 167 >UniRef50_Q235V6 Cluster: Oxidoreductase, aldo/keto reductase family protein; n=2; Tetrahymena thermophila SB210|Rep: Oxidoreductase, aldo/keto reductase family protein - Tetrahymena thermophila SB210 Length = 332 Score = 107 bits (257), Expect = 8e-22 Identities = 63/173 (36%), Positives = 99/173 (57%), Gaps = 1/173 (0%) Frame = +1 Query: 136 LSNGAKIPVIGIGTWK-SKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQE 312 L+NG +P++G+GT+ + E+T ++ A+D GYRHI A Y NE +GE++KT +E Sbjct: 10 LNNGQIMPLVGLGTYLLNSKEEMTNLLRTALDAGYRHIDTAVNYQNEAMIGESLKTIFKE 69 Query: 313 GVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPT 492 G R+DLFI SK++ ++ + +++ SL+ L +DY+DLY +H+P + + Sbjct: 70 GKYSRKDLFIVSKVFP--NKGINMLESVKKSLKELQLDYVDLYYLHFPLGFLSE------ 121 Query: 493 DADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKP 651 K +F + W LE GL +S+GVSNFN L +L A VKP Sbjct: 122 ----KEEFVHLPVHVAWAQLEEAHRLGLAKSIGVSNFNVMALADLLSYAKVKP 170 >UniRef50_A2QB88 Cluster: Contig An01c0460, complete genome. precursor; n=1; Aspergillus niger|Rep: Contig An01c0460, complete genome. precursor - Aspergillus niger Length = 351 Score = 107 bits (257), Expect = 8e-22 Identities = 68/178 (38%), Positives = 100/178 (56%), Gaps = 13/178 (7%) Frame = +1 Query: 157 PVIGIGTWKSKPGE--VTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQEGVVKRE 330 P +G+GT++ G V +AV A+ GYRHI A YGNE EVGEAIK E + RE Sbjct: 47 PAVGLGTFQGDAGNRGVKEAVLQALRCGYRHIDTATAYGNEIEVGEAIK----ESRIPRE 102 Query: 331 DLFITSKLWNTFHRPDLVRGALEVSLRNLNIDY-LDLYLIHWPQAYKEDDAIFPTDADGK 507 ++ +T+KL T+HR V AL++SL L ++Y L ++L + +Y A P + Sbjct: 103 EIIVTTKLAQTWHRVSDVERALDLSLERLQLNYGLSMHL-YSASSYSVPHAYSPGPDNNT 161 Query: 508 IQFSDV----------DYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKP 651 I+ + DY TW A+E LV G ++ +GVSNFN +L+R+L +A + P Sbjct: 162 IRHPNGKPIIDHELSRDYPSTWAAMESLVDKGKLKMIGVSNFNILKLERLLGSARIPP 219 Score = 34.7 bits (76), Expect = 6.8 Identities = 14/35 (40%), Positives = 19/35 (54%) Frame = +2 Query: 659 NQVECHPYLNXKRLKQFCEDRDIMITXYSPXGXLP 763 NQ+E HPYL L +FC+ I + + P G P Sbjct: 222 NQIELHPYLPQVELVRFCKANGIHLVAHQPLGGKP 256 >UniRef50_Q8ET73 Cluster: 2,5-diketo-D-gluconate reductase; n=12; Bacteria|Rep: 2,5-diketo-D-gluconate reductase - Oceanobacillus iheyensis Length = 280 Score = 107 bits (256), Expect = 1e-21 Identities = 65/181 (35%), Positives = 90/181 (49%) Frame = +1 Query: 109 IMTSVPVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGE 288 ++ +P TL +G IP +G GT++ + QA+ +AID GYR I A+ Y NE VGE Sbjct: 1 MVNQIPNVTLHDGLTIPKVGFGTYRLNGNDGVQAINNAIDHGYRLIDTAYNYENEGTVGE 60 Query: 289 AIKTKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYK 468 A++ RE L ITSKL +H D ++ SL N+DY DLYLIHWP Sbjct: 61 AVR----RSSTPREQLLITSKLPGRYHHYDKAVTTIQESLYRANLDYYDLYLIHWPN--- 113 Query: 469 EDDAIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVK 648 D+ YV+ W+AL G +RS+GV NF + L+R+ Sbjct: 114 --------------PIQDI-YVEAWQALIEAKRRGYIRSIGVCNFLPEHLERLKQETGEL 158 Query: 649 P 651 P Sbjct: 159 P 159 >UniRef50_Q043M4 Cluster: Aldo/keto reductase of diketogulonate reductase family; n=2; Lactobacillus|Rep: Aldo/keto reductase of diketogulonate reductase family - Lactobacillus gasseri (strain ATCC 33323 / DSM 20243) Length = 273 Score = 107 bits (256), Expect = 1e-21 Identities = 63/173 (36%), Positives = 92/173 (53%) Frame = +1 Query: 133 TLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQE 312 TL+N KIP+ G GT++ P + QAV A + GYR I A Y NE++VGEA+K Sbjct: 5 TLNNDVKIPIFGFGTYEISPDQTKQAVLSAFEEGYRLIDTAQYYQNEQQVGEAVKA---- 60 Query: 313 GVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPT 492 + R+++FIT+K + + L+ SLR + +DY DL LIHWP + Sbjct: 61 SGLNRDEVFITTKTMTDGYEDTKI--GLDESLRRIGLDYFDLVLIHWPMGHD-------- 110 Query: 493 DADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKP 651 +DTW ALE G R++G+SNFNS+Q ++ +SV+P Sbjct: 111 -------------IDTWHALEAAYKAGKTRAIGISNFNSRQTLDLIHQSSVRP 150 >UniRef50_A0JX62 Cluster: 2,5-didehydrogluconate reductase; n=9; Bacteria|Rep: 2,5-didehydrogluconate reductase - Arthrobacter sp. (strain FB24) Length = 291 Score = 106 bits (255), Expect = 1e-21 Identities = 82/261 (31%), Positives = 124/261 (47%), Gaps = 13/261 (4%) Frame = +1 Query: 112 MTSVPVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEA 291 M + P +L+NG I +G G +K P + V A++ GYRH A +YGNE VG+A Sbjct: 1 MKNSPRLSLNNGVLIDQLGFGLYKVPPADAAGLVTMALEAGYRHFDTAAMYGNETGVGKA 60 Query: 292 IKTKIQ-----------EGV--VKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYL 432 I E + REDLF+T+K+WN H D A + S+ NL ++Y+ Sbjct: 61 IGALAGFAGGGPAGGSGEAAPSLSREDLFVTTKVWNDDHGYDATMRAFDTSMSNLGMEYV 120 Query: 433 DLYLIHWPQAYKEDDAIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSK 612 DLYLIHWP A + +F ++++A+E L G +R++GVSNF Sbjct: 121 DLYLIHWPCARR---GLF---------------TESYRAMETLYREGRIRAIGVSNFQPA 162 Query: 613 QLQRILDNASVKPGH*PGRMPSVFKPXAIEAVLRRP*YYDNGVLPRWGXPDRPWAKPGDP 792 L+ +L+ A V P + P + LR+ +D R G W+ G Sbjct: 163 HLEHLLETAEVVPAVNQIEL----HPWLQQDELRQ--LHD-----RLGIRTEAWSPLGRG 211 Query: 793 HLMEDPKLKEIADRLGKXAAQ 855 ++ DP + E+A + AAQ Sbjct: 212 QVLADPVVLELAAAHRRSAAQ 232 >UniRef50_Q929C8 Cluster: Lin2349 protein; n=12; Listeria|Rep: Lin2349 protein - Listeria innocua Length = 294 Score = 106 bits (254), Expect = 2e-21 Identities = 70/173 (40%), Positives = 93/173 (53%), Gaps = 1/173 (0%) Frame = +1 Query: 136 LSNGAKIPVIGIGTWKSKPGE-VTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQE 312 L IP IG+G ++ E + AV+ AI++GYR A VY NE VG+AI + Sbjct: 11 LPGNETIPYIGLGVFQVTEQEFIAGAVEKAIEVGYRLFDTAAVYNNEAIVGQAIL----D 66 Query: 313 GVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPT 492 V RE+LFI+SK+WN D A E +LRNL +DYLDLYLIHWP A K Sbjct: 67 SAVPREELFISSKVWNGDLGYDETLFAFERTLRNLKLDYLDLYLIHWPVAGK-------- 118 Query: 493 DADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKP 651 Y D+W+A+E L L++S+GV+NF L +L A+ KP Sbjct: 119 ------------YRDSWRAMERLHDEKLIKSIGVANFKQHHLSDLLVAANEKP 159 >UniRef50_Q5FKI1 Cluster: Reductase-dehydrogenase; n=1; Lactobacillus acidophilus|Rep: Reductase-dehydrogenase - Lactobacillus acidophilus Length = 271 Score = 106 bits (254), Expect = 2e-21 Identities = 60/172 (34%), Positives = 94/172 (54%) Frame = +1 Query: 136 LSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQEG 315 L+NG KIP I +GTW EV + V+ A++IGYR A YGNE VG+ I Sbjct: 9 LNNGEKIPQIQLGTWLINNDEVNKVVRQAVNIGYRGFDTAKDYGNESGVGKG----IWNS 64 Query: 316 VVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTD 495 ++R D+F+T+KL + + A++ +L ++Y+DL LIH PQ + E + Sbjct: 65 DIERSDIFLTTKLPTAVKDYEGTKKAIDAALDKFGLEYIDLLLIHSPQPWIEVNRTNDRH 124 Query: 496 ADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKP 651 G + + W+A+E V G VRS+GVSNF + ++ I++N ++ P Sbjct: 125 FKGNL--------ENWRAMEEAVKAGKVRSIGVSNFLQEDIENIVNNGTITP 168 >UniRef50_A5AD50 Cluster: Putative uncharacterized protein; n=3; Magnoliophyta|Rep: Putative uncharacterized protein - Vitis vinifera (Grape) Length = 304 Score = 106 bits (254), Expect = 2e-21 Identities = 48/76 (63%), Positives = 59/76 (77%) Frame = +1 Query: 136 LSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQEG 315 L+ GAK+P +G+GTW+S PG V QAV AI +GYRHI CA VYGNE+E+G +K +G Sbjct: 10 LNTGAKMPSVGLGTWQSDPGLVGQAVAIAIKVGYRHIDCAQVYGNEEEIGIVLKKLFDDG 69 Query: 316 VVKREDLFITSKLWNT 363 VVKREDL+ITSKLW T Sbjct: 70 VVKREDLWITSKLWCT 85 Score = 36.3 bits (80), Expect = 2.2 Identities = 13/31 (41%), Positives = 19/31 (61%) Frame = +2 Query: 662 QVECHPYLNXKRLKQFCEDRDIMITXYSPXG 754 QVECHP +L FC+ + + +T +SP G Sbjct: 161 QVECHPSWQQSKLHAFCKSKGVHLTGFSPLG 191 >UniRef50_O13848 Cluster: NADH/NADPH dependent indole-3-acetaldehyde reductase AKR3C2; n=1; Schizosaccharomyces pombe|Rep: NADH/NADPH dependent indole-3-acetaldehyde reductase AKR3C2 - Schizosaccharomyces pombe (Fission yeast) Length = 284 Score = 106 bits (254), Expect = 2e-21 Identities = 75/177 (42%), Positives = 99/177 (55%), Gaps = 8/177 (4%) Frame = +1 Query: 145 GAKIPV--IGIGT--WKSKPGEVTQ----AVKDAIDIGYRHIXCAFVYGNEKEVGEAIKT 300 G KIPV G+GT +K + GE+ + +VK+A+ G+ HI CA VYGNE+EVG A+K Sbjct: 7 GPKIPVPAYGVGTALFKKEKGEINRTIVDSVKNALAAGFIHIDCAEVYGNEEEVGVALK- 65 Query: 301 KIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDA 480 E V R LFITSK+ H D + AL SLR L DYLDLYL+H P + E Sbjct: 66 ---EANVPRSKLFITSKV---MHNVDNIPEALNESLRKLGTDYLDLYLLHSPIPFYEK-- 117 Query: 481 IFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKP 651 KI S + WKA+E + GLV S+GVSNF L+ +L +++ P Sbjct: 118 --------KIPIS-----EGWKAMETALGTGLVHSVGVSNFRIPDLEELLKTSTITP 161 >UniRef50_UPI00006CA3CB Cluster: oxidoreductase, aldo/keto reductase family protein; n=3; Tetrahymena thermophila SB210|Rep: oxidoreductase, aldo/keto reductase family protein - Tetrahymena thermophila SB210 Length = 299 Score = 105 bits (253), Expect = 2e-21 Identities = 64/176 (36%), Positives = 94/176 (53%), Gaps = 1/176 (0%) Frame = +1 Query: 127 VTTLSNGAKIPVIGIGTWKSKP-GEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTK 303 V TLSNG K+P G+G+ + + EVT ++ A+D+GYRHI A +Y NE+ +G A+KT Sbjct: 9 VITLSNGQKMPAFGLGSSRVQSVEEVTNLIRKALDVGYRHIDTAQMYENEQFIGAALKTI 68 Query: 304 IQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAI 483 EG KRED+F+ +K + ++ L+ L +DY+DL LIH P A DD Sbjct: 69 FGEGKYKREDIFLVTK--QASIKGVSCLEIMKEQLQKLQVDYVDLLLIHVPLAAPSDD-- 124 Query: 484 FPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKP 651 Q++ W E + GL + LGVSNFN + + +L +KP Sbjct: 125 -------YQQWNHKPVHQIWAEFEEIHSLGLAKGLGVSNFNCQMIIDLLAYCKIKP 173 >UniRef50_UPI0000DB6EE9 Cluster: PREDICTED: similar to C35D10.6; n=2; Endopterygota|Rep: PREDICTED: similar to C35D10.6 - Apis mellifera Length = 292 Score = 105 bits (252), Expect = 3e-21 Identities = 62/169 (36%), Positives = 95/169 (56%), Gaps = 2/169 (1%) Frame = +1 Query: 136 LSNGAKIPVIGIGTWKSKPGE-VTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQE 312 LS+G +P+IG GT+K + E V Q V +++++G+R I A Y NE+++G A+K + + Sbjct: 10 LSSGYDMPLIGFGTYKIQGRELVYQVVDESLNVGFRSIDTAVGYRNEEDIGYALKNLLPK 69 Query: 313 GVVKREDLFITSKLWNTFH-RPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFP 489 ++R D+FIT+KL + + P + ++ SL+ N Y+DLYLIHWP A + P Sbjct: 70 YNLQRSDIFITTKLPPSVNGDPKGIEQCVQKSLKAFNTTYIDLYLIHWPGATR-----IP 124 Query: 490 TDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDN 636 + TW L L G +RS+GVSNF K LQ +L N Sbjct: 125 ETSTNNPSLR----AKTWNKLVDLKKQGFIRSIGVSNFTIKHLQELLQN 169 >UniRef50_Q4JX70 Cluster: Putative oxidoreductase; n=1; Corynebacterium jeikeium K411|Rep: Putative oxidoreductase - Corynebacterium jeikeium (strain K411) Length = 285 Score = 105 bits (252), Expect = 3e-21 Identities = 52/134 (38%), Positives = 80/134 (59%) Frame = +1 Query: 118 SVPVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIK 297 +VP +++G P +G+G W+ + +V+ AI+ GYRHI A +YGNE+ VG A+ Sbjct: 7 AVPTLEMNDGKTTPQLGLGVWQLSDEDTYTSVRAAIETGYRHIDTAAIYGNEEAVGRAVA 66 Query: 298 TKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDD 477 ++ G V+RE+LFIT+KLWN + A S + L +DY+DLYL+HWP + D Sbjct: 67 DAVKAGDVQREELFITTKLWNADQA--CGKEAFAESQKKLGMDYVDLYLLHWP-CPQADS 123 Query: 478 AIFPTDADGKIQFS 519 + D+ +IQ S Sbjct: 124 FVQAYDSMAEIQQS 137 >UniRef50_P82125 Cluster: 1,5-anhydro-D-fructose reductase; n=1; Sus scrofa|Rep: 1,5-anhydro-D-fructose reductase - Sus scrofa (Pig) Length = 206 Score = 105 bits (252), Expect = 3e-21 Identities = 60/128 (46%), Positives = 73/128 (57%), Gaps = 1/128 (0%) Frame = +1 Query: 151 KIPVIGIGTWKSKPG-EVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQEGVVKR 327 KIPV+G+GTW++ PG EVT+AVK AID GYRH A++Y NE EVG I+ KI EGVV+R Sbjct: 1 KIPVLGLGTWQAAPGGEVTEAVKVAIDTGYRHPDSAYLYHNEDEVGVGIQAKIDEGVVRR 60 Query: 328 EDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTDADGK 507 EDLFI SK YLDL IHWP +K + P D G Sbjct: 61 EDLFIVSK----------------------KXXYLDLXNIHWPMQFKPGEVDLPVDRSGM 98 Query: 508 IQFSDVDY 531 I S+ D+ Sbjct: 99 IVASNTDF 106 Score = 36.7 bits (81), Expect = 1.7 Identities = 16/34 (47%), Positives = 21/34 (61%) Frame = +2 Query: 653 VTNQVECHPYLNXKRLKQFCEDRDIMITXYSPXG 754 VTNQ+E HPYL K F + R++ +T Y P G Sbjct: 110 VTNQIESHPYLTQK--ISFXQSRNVSVTAYRPLG 141 >UniRef50_Q17568 Cluster: Putative uncharacterized protein; n=1; Caenorhabditis elegans|Rep: Putative uncharacterized protein - Caenorhabditis elegans Length = 287 Score = 105 bits (251), Expect = 4e-21 Identities = 57/174 (32%), Positives = 101/174 (58%), Gaps = 2/174 (1%) Frame = +1 Query: 136 LSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQEG 315 L NG +IP + +GT+++K ++ AV +A+ +GYR A Y NEK++G A+KT + Sbjct: 4 LKNGQEIPKLALGTYEAKGDQLFAAVDEALKVGYRSFDTAKYYENEKDLGLALKTLLPRH 63 Query: 316 VVKREDLFITSKL--WNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFP 489 + ED+++TSK+ +++ + +L+R + SL L+ YLDL L+H+P+ P Sbjct: 64 NICSEDIYLTSKVFPYSSKNAAELIRKDVNESLELLDRKYLDLVLVHYPR---------P 114 Query: 490 TDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKP 651 D + + + + DTW ALE L G +RS+GVSN+ ++ + +++P Sbjct: 115 LDTEDLNENNKMYRKDTWIALEKLHAEGKIRSIGVSNYEPHHIEEMRSYITIEP 168 Score = 34.7 bits (76), Expect = 6.8 Identities = 12/32 (37%), Positives = 19/32 (59%) Frame = +2 Query: 659 NQVECHPYLNXKRLKQFCEDRDIMITXYSPXG 754 NQ+E HP+ K L+ +C +I+ +SP G Sbjct: 171 NQIEYHPHFQRKVLRAYCNKNEILFQAFSPLG 202 >UniRef50_Q927E1 Cluster: Lin2848 protein; n=13; Listeria|Rep: Lin2848 protein - Listeria innocua Length = 280 Score = 104 bits (250), Expect = 6e-21 Identities = 62/173 (35%), Positives = 96/173 (55%), Gaps = 1/173 (0%) Frame = +1 Query: 136 LSNGAKIPVIGIGTWK-SKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQE 312 L+NG ++P G G +K + + A++ A+D+GYR A Y NEKE+G+ + Sbjct: 11 LNNGIEMPRHGFGVYKLTDEQRMRTALETAVDVGYRLFDTASFYHNEKELGDFFASS--- 67 Query: 313 GVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPT 492 +KR++ F+T+K+WNT D A E S + L +D +DLYL+HWP K+D Sbjct: 68 -GLKRDEFFVTTKMWNTEQGYDETLRAFEKSQKKLQLDQVDLYLVHWP---KQD------ 117 Query: 493 DADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKP 651 + +TW+A+E L GLVR++GVSNF + L R+ +A+V P Sbjct: 118 -----------TFFETWRAVEKLYDEGLVRAIGVSNFEAHHLDRLRTSANVLP 159 >UniRef50_Q5BLA6 Cluster: Zgc:110782; n=2; Danio rerio|Rep: Zgc:110782 - Danio rerio (Zebrafish) (Brachydanio rerio) Length = 287 Score = 104 bits (249), Expect = 7e-21 Identities = 62/178 (34%), Positives = 99/178 (55%), Gaps = 1/178 (0%) Frame = +1 Query: 121 VPVTTLSNGAKIPVIGIGTWKSKPGE-VTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIK 297 VP L +G ++P++G+GT+K + E + Q+V A+ GYR A VYGNE +G+ +K Sbjct: 3 VPSVRLMSGTQMPLLGLGTYKLQDHEQLKQSVSCALQAGYRAFDTAAVYGNEAHLGQVLK 62 Query: 298 TKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDD 477 + + + RED+FI SKL + H G L SL L+ +Y+DLYLIHWP + Sbjct: 63 ELLPKYGLIREDVFIISKLAPSDHGLRAKEGCLR-SLEQLDCEYIDLYLIHWPGM----E 117 Query: 478 AIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKP 651 + P D+ + S+ +W LE G +++GVSN+ +K ++ +L + V P Sbjct: 118 GLDPEDS----RHSEY-RAQSWATLEEFHASGQFKAIGVSNYTAKHIRELLASCRVPP 170 >UniRef50_Q18483 Cluster: Putative uncharacterized protein; n=2; Caenorhabditis|Rep: Putative uncharacterized protein - Caenorhabditis elegans Length = 287 Score = 104 bits (249), Expect = 7e-21 Identities = 60/167 (35%), Positives = 97/167 (58%), Gaps = 1/167 (0%) Frame = +1 Query: 154 IPVIGIGTWKSKPGEVTQAVKDA-IDIGYRHIXCAFVYGNEKEVGEAIKTKIQEGVVKRE 330 +P+IGIGTW+ + E+ + V DA GYR I A VY NE ++G ++ + +KRE Sbjct: 11 MPLIGIGTWQVQKEEILRQVIDAGFKEGYRFIDTAQVYNNEAKIGRILEKLLPANGLKRE 70 Query: 331 DLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTDADGKI 510 D++ITSKL + R ++E SL NL ++YLDL LIHWP + + + A+ K+ Sbjct: 71 DIWITSKLAPSNAGVKKARESIEESLSNLKVEYLDLLLIHWPGSSLKSE----NPANKKL 126 Query: 511 QFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKP 651 + V++W + ++ G +RS+GVSNF L+ + +++V P Sbjct: 127 R------VESWNVMCEMMAEGKLRSVGVSNFEICHLEELKKDSNVVP 167 >UniRef50_Q568D7 Cluster: Zgc:110366; n=7; Euteleostomi|Rep: Zgc:110366 - Danio rerio (Zebrafish) (Brachydanio rerio) Length = 289 Score = 103 bits (248), Expect = 1e-20 Identities = 65/179 (36%), Positives = 98/179 (54%), Gaps = 1/179 (0%) Frame = +1 Query: 118 SVPVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAI-DIGYRHIXCAFVYGNEKEVGEAI 294 S P L NG IP++G+GT G +AV A+ + G RHI A YG E+ +G+A+ Sbjct: 12 SCPAVPLHNGLNIPILGLGT-SHYGGYSHEAVLYALQECGIRHIDTAKRYGCEEALGKAV 70 Query: 295 KTKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKED 474 E V+RE+L++T+KLW + + A S L +DYLDLYL+HWP Sbjct: 71 T----ESGVQREELWVTTKLWPGDYGYQSTKQACRDSRARLGVDYLDLYLMHWP------ 120 Query: 475 DAIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKP 651 D++ P + +++ ++TW+ALE L GL R++GVSNF L + D+ + P Sbjct: 121 DSMVPGRSSQEVR------LETWRALEELYDEGLCRAIGVSNFLIPHLNELKDSGGIVP 173 >UniRef50_Q7WSY4 Cluster: Putative aldo-keto reductase; n=1; Propionibacterium freudenreichii subsp. shermanii|Rep: Putative aldo-keto reductase - Propionibacterium freudenreichii subsp. shermanii Length = 280 Score = 103 bits (247), Expect = 1e-20 Identities = 60/172 (34%), Positives = 89/172 (51%) Frame = +1 Query: 115 TSVPVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAI 294 T P LS G ++P++G+GTW K E AV AI+ GYR + A YGNE+ VG+A+ Sbjct: 6 TPTPTVELSGGTRMPMLGMGTWPLKGEECRAAVASAIEQGYRLVDTAEAYGNEEAVGKAV 65 Query: 295 KTKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKED 474 + E R ++F+T+K +H V ALE SL L +DY+DL+L+HWP Sbjct: 66 R----EAGPDRAEIFVTTKFSKQWHSRKGVHEALEHSLERLGLDYVDLFLMHWPMP---- 117 Query: 475 DAIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRIL 630 + YVD ++ + L GL +++GVSNF L ++ Sbjct: 118 --------------GEGSYVDAYRGMVELKEQGLAKAIGVSNFKVHHLDDLI 155 >UniRef50_A3VHZ9 Cluster: Oxidoreductase; n=1; Rhodobacterales bacterium HTCC2654|Rep: Oxidoreductase - Rhodobacterales bacterium HTCC2654 Length = 278 Score = 103 bits (247), Expect = 1e-20 Identities = 61/160 (38%), Positives = 87/160 (54%) Frame = +1 Query: 124 PVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTK 303 P TL+NG ++P +G+GTW E +AV AI+ GYR I A Y NE VG+ I+ Sbjct: 8 PTVTLANGVEMPQLGLGTWPMTDDEAAKAVATAIETGYRLIDTAENYKNETGVGQGIR-- 65 Query: 304 IQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAI 483 + V R+++F+T+K+ +H D R A E SL L +DY+DL+LIHWP Sbjct: 66 --DAGVARDEVFLTTKMNKQWHSVDGARRACEASLERLGLDYIDLFLIHWPN-------- 115 Query: 484 FPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNF 603 P YV+ ++ L L+ GLVR++G SNF Sbjct: 116 -PDQG---------TYVEAFEGLTRLLDAGLVRAIGTSNF 145 >UniRef50_Q572D2 Cluster: Aldo-keto reductase, putative; n=1; Phytophthora infestans|Rep: Aldo-keto reductase, putative - Phytophthora infestans (Potato late blight fungus) Length = 255 Score = 103 bits (247), Expect = 1e-20 Identities = 64/179 (35%), Positives = 97/179 (54%), Gaps = 1/179 (0%) Frame = +1 Query: 118 SVPVTTLSNGAKIPVIGIGTWKSKPG-EVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAI 294 +VP L +GA+IP+IG+G ++S+PG E A+ ++ +GYRHI A +YGNE++VG A+ Sbjct: 4 NVPTKILPSGARIPMIGLGVYQSEPGPETYNAILTSLKLGYRHIDTAEIYGNEEDVGRAV 63 Query: 295 KTKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKED 474 + + + RE++F+T+KL+ T A + S L I Y+ LYL+H P KE Sbjct: 64 R----DSGIPREEIFVTTKLFTTNWGYSKALAAGKASNDRLGIVYIYLYLLHAPGPPKE- 118 Query: 475 DAIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKP 651 DTW+A+E L +R +GVSNFN L + A +KP Sbjct: 119 ------------------RADTWRAVEDLREQETLRDIGVSNFNETLLATLRKTAHIKP 159 >UniRef50_Q88TV9 Cluster: Oxidoreductase; n=4; Lactobacillus|Rep: Oxidoreductase - Lactobacillus plantarum Length = 288 Score = 103 bits (246), Expect = 2e-20 Identities = 67/181 (37%), Positives = 93/181 (51%), Gaps = 1/181 (0%) Frame = +1 Query: 112 MTSVPVTTLSNGAKIPVIGIGTWK-SKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGE 288 MT P TL++G IP IG GT++ G QAVK+A+ IGYRHI A Y NE EVG+ Sbjct: 1 MTKTPTITLNDGRAIPAIGFGTFQIPDDGSTYQAVKEALVIGYRHIDTAVAYFNEDEVGQ 60 Query: 289 AIKTKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYK 468 AIK + + R+ +++TSKLW + D A++ SL L +DY+DLYLIH P Sbjct: 61 AIK----DSGIPRDQIWVTSKLWLQDYGFDAASRAIDRSLTKLRLDYIDLYLIHQP---- 112 Query: 469 EDDAIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVK 648 + DV W+A+E G ++S+GVSN Q+ + Sbjct: 113 ---------------YGDVP--GAWQAMEAAQKAGKLKSIGVSNMTPTLWQKFVPQFETI 155 Query: 649 P 651 P Sbjct: 156 P 156 >UniRef50_Q3E9M9 Cluster: Uncharacterized protein At5g01670.2; n=7; Magnoliophyta|Rep: Uncharacterized protein At5g01670.2 - Arabidopsis thaliana (Mouse-ear cress) Length = 349 Score = 103 bits (246), Expect = 2e-20 Identities = 70/199 (35%), Positives = 101/199 (50%), Gaps = 27/199 (13%) Frame = +1 Query: 136 LSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQEG 315 L +G KIP +G+GTW+S V ++ GYRHI A+ YG+++EVG+ IK + G Sbjct: 18 LLSGHKIPAVGLGTWRSGSQAAHAVVTAIVEGGYRHIDTAWEYGDQREVGQGIKRAMHAG 77 Query: 316 VVKREDLFIT----------------SKLWN-----------TFHRPDLVRGALEVSLRN 414 + +R DLF+T S L N T P+ VR AL+ +L+ Sbjct: 78 L-ERRDLFVTSKLWYTLILRKMINLSSPLMNVLVGTCLNKRCTELSPERVRPALQNTLKE 136 Query: 415 LNIDYLDLYLIHWPQAYKEDDAIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGV 594 L ++YLDLYLIHWP +E + P D D D W+ +E L LVR++GV Sbjct: 137 LQLEYLDLYLIHWPIRLREGASKPPKAGD----VLDFDMEGVWREMENLSKDSLVRNIGV 192 Query: 595 SNFNSKQLQRILDNASVKP 651 NF +L ++L A + P Sbjct: 193 CNFTVTKLNKLLGFAELIP 211 >UniRef50_Q9A2X8 Cluster: Oxidoreductase, aldo/keto reductase family; n=3; Caulobacter|Rep: Oxidoreductase, aldo/keto reductase family - Caulobacter crescentus (Caulobacter vibrioides) Length = 279 Score = 102 bits (245), Expect = 2e-20 Identities = 62/171 (36%), Positives = 93/171 (54%), Gaps = 1/171 (0%) Frame = +1 Query: 112 MTSVPVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEA 291 M+ + S +P +G GTW+ + G V+ A++IGYRHI A +YGNE++VG A Sbjct: 1 MSKLVPAVRSGDVLMPALGFGTWQLENGTAVPLVEKALEIGYRHIDTAQIYGNERDVGAA 60 Query: 292 IKTKIQEGVVKREDLFITSKLW-NTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYK 468 I+ VKR+++F+T+K+W + F DL R A E SL L +D +DL L+HWP+ Sbjct: 61 IR----NSGVKRDEIFLTTKVWIDQFADGDLQRSA-EKSLEKLGVDQVDLLLLHWPK--- 112 Query: 469 EDDAIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQ 621 +V +T KAL + G R++G+SNF S QL+ Sbjct: 113 ----------------PEVPLAETLKALNAVRAKGWTRAIGLSNFPSAQLE 147 Score = 35.9 bits (79), Expect = 3.0 Identities = 19/43 (44%), Positives = 25/43 (58%), Gaps = 2/43 (4%) Frame = +2 Query: 656 TNQVECHPYLNXKRLKQFCEDRDIMITXYSP--XGXLPTDPGL 778 T+QVE HPYL+ K LK + + IT +SP G + DP L Sbjct: 159 TDQVEYHPYLSLKTLKAKADQLGVSITAWSPLAQGKVAQDPVL 201 >UniRef50_Q54NR2 Cluster: Aldo-keto reductase; n=3; Dictyostelium discoideum AX4|Rep: Aldo-keto reductase - Dictyostelium discoideum AX4 Length = 305 Score = 102 bits (244), Expect = 3e-20 Identities = 64/178 (35%), Positives = 92/178 (51%), Gaps = 8/178 (4%) Frame = +1 Query: 142 NGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKI--QEG 315 N K+P++GIGT+K ++ +K ++ GYR I A +Y NE+ +G+ + + +G Sbjct: 23 NPIKMPMLGIGTFKLN--DIENIIKVGLENGYRRIDTASMYNNEERIGKVLNEMVTKNDG 80 Query: 316 V----VKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAI 483 + +KREDLFITSK + A E SL+ L +DYLD YLIHWP Sbjct: 81 LDGKKIKREDLFITSKCSFMEQGYENALKAFESSLKKLQLDYLDCYLIHWPGV------- 133 Query: 484 FPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILD--NASVKP 651 DG + + TW+ALE L VRS+GVSN+ L +L N +KP Sbjct: 134 --KGLDGSDSGNSIQRAQTWRALEKLYQDKKVRSIGVSNYTINHLTELLSSPNLQIKP 189 >UniRef50_A5VK30 Cluster: 2,5-didehydrogluconate reductase; n=2; Lactobacillus reuteri|Rep: 2,5-didehydrogluconate reductase - Lactobacillus reuteri F275 Length = 300 Score = 101 bits (243), Expect = 4e-20 Identities = 61/177 (34%), Positives = 94/177 (53%), Gaps = 1/177 (0%) Frame = +1 Query: 124 PVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTK 303 P L+NG IP +G+G WK+ E Q VK+AI Y I A YGNE VG+ I+ Sbjct: 11 PKIKLNNGHLIPQLGLGVWKASLAETQQMVKEAIMNDYVLIDTAKQYGNEAAVGQGIQDG 70 Query: 304 IQEGVVKREDLFITSKLWNTFHRP-DLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDA 480 + KR+ +F+T+K++N D +R A+ L+ L +Y+DL L+HWP K Sbjct: 71 FKATGRKRDSIFLTTKIFNGDQGDYDKLRQAVNEQLKKLQTNYVDLLLLHWPVNDK---- 126 Query: 481 IFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKP 651 Y ++W+ALE + G +++GV NFN +++ +LD+A +KP Sbjct: 127 ----------------YNESWRALEDIYKDGQAKAIGVCNFNVERMTDLLDHAKIKP 167 >UniRef50_P47137 Cluster: Probable oxidoreductase YJR096W; n=8; Saccharomycetales|Rep: Probable oxidoreductase YJR096W - Saccharomyces cerevisiae (Baker's yeast) Length = 282 Score = 101 bits (243), Expect = 4e-20 Identities = 61/174 (35%), Positives = 95/174 (54%), Gaps = 3/174 (1%) Frame = +1 Query: 136 LSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQE- 312 LSNG KIP I +GT+ + + V + + GYRH A +YGNEKEVG+ I + E Sbjct: 8 LSNGFKIPSIALGTYDIPRSQTAEIVYEGVKCGYRHFDTAVLYGNEKEVGDGIIKWLNED 67 Query: 313 -GVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLN-IDYLDLYLIHWPQAYKEDDAIF 486 G KRE++F T+KLWN+ + + A+ L ++ + Y+DL LIH P Sbjct: 68 PGNHKREEIFYTTKLWNSQNGYKRAKAAIRQCLNEVSGLQYIDLLLIHSPL--------- 118 Query: 487 PTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVK 648 K++ ++TW+A++ V GLV+S+GVSN+ K + +L+ +K Sbjct: 119 ---EGSKLR------LETWRAMQEAVDEGLVKSIGVSNYGKKHIDELLNWPELK 163 >UniRef50_Q02198 Cluster: Morphine 6-dehydrogenase; n=5; Bacteria|Rep: Morphine 6-dehydrogenase - Pseudomonas putida Length = 296 Score = 101 bits (243), Expect = 4e-20 Identities = 76/246 (30%), Positives = 113/246 (45%), Gaps = 2/246 (0%) Frame = +1 Query: 124 PVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTK 303 P+ L+NG K+P +G+G + + E A+ AI GYR I A Y NE +VGE I+ Sbjct: 6 PLINLNNGVKMPALGLGVFAASAEETASAIASAISSGYRLIDTARSYNNEAQVGEGIR-- 63 Query: 304 IQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAI 483 V R ++F+T+KL+N + + A + SL L +DY+DLYL+HWP Sbjct: 64 --NSGVDRAEMFVTTKLFNCDYGYERALRAFDESLGRLGLDYVDLYLLHWP--------- 112 Query: 484 FPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPGH*P 663 D + IQ +WKA E ++ G R++GV NF QL ++ + V P Sbjct: 113 -TKDWNATIQ--------SWKAAEKILGDGRARAIGVCNFLEDQLDELIAASDVVPAVNQ 163 Query: 664 GRMPSVFKPXAIEAVLRRP*YYDNGVLPRWGXPDRPWA--KPGDPHLMEDPKLKEIADRL 837 + F + A R P G + G H + DP + IA+ Sbjct: 164 IELHPYFAQKPLLAKNRALGIVTEAWSPIGGAINDGDGDNHGGRKHPLTDPVITTIAEAH 223 Query: 838 GKXAAQ 855 G+ AAQ Sbjct: 224 GRSAAQ 229 >UniRef50_P91997 Cluster: Putative uncharacterized protein; n=4; Caenorhabditis|Rep: Putative uncharacterized protein - Caenorhabditis elegans Length = 297 Score = 101 bits (242), Expect = 5e-20 Identities = 61/174 (35%), Positives = 96/174 (55%), Gaps = 2/174 (1%) Frame = +1 Query: 136 LSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQEG 315 L++G IP +G GT+K V A+ A+ GYR A Y NEKE+GEA+K + + Sbjct: 15 LNSGYNIPFVGFGTYKVTGENVPPAIDAALTAGYRMFDTAKYYLNEKELGEALKILLPKH 74 Query: 316 VVKREDLFITSKLW-NTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPT 492 + R D+F+TSK + + + + RG +E SL++L DY+D+YL+H+P+ P Sbjct: 75 GLSRSDVFLTSKFFPESKNCREACRGFVEESLQSLQTDYIDMYLVHYPK---------PN 125 Query: 493 DADGKIQFSDVDYVD-TWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKP 651 D+D ++ +Y ++ LE G VRS+GVSN+ L+ + A V P Sbjct: 126 DSDND-DVNNAEYRKIAYEVLEEAKAAGKVRSIGVSNYEIVHLEELKTYAKVPP 178 >UniRef50_A4FEB9 Cluster: 2,5-diketo-D-gluconic acid reductase; n=1; Saccharopolyspora erythraea NRRL 2338|Rep: 2,5-diketo-D-gluconic acid reductase - Saccharopolyspora erythraea (strain NRRL 23338) Length = 159 Score = 101 bits (241), Expect = 7e-20 Identities = 52/115 (45%), Positives = 69/115 (60%) Frame = +1 Query: 112 MTSVPVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEA 291 MTSVP TL+NG ++P +G G ++ E AV A++ GYR I A YGNE VG A Sbjct: 1 MTSVPTVTLNNGVEMPQLGYGVFQVPEDETAAAVGAALEAGYRSIDTAAAYGNEAAVGRA 60 Query: 292 IKTKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWP 456 + G+ R++LF+T+KLWN D A + SL L +D+LDLYLIHWP Sbjct: 61 L---AGSGLA-RDELFVTTKLWNADQGYDNALRAFDTSLELLGLDHLDLYLIHWP 111 >UniRef50_Q5XJM7 Cluster: Zgc:101765; n=5; Eumetazoa|Rep: Zgc:101765 - Danio rerio (Zebrafish) (Brachydanio rerio) Length = 288 Score = 100 bits (239), Expect = 1e-19 Identities = 75/247 (30%), Positives = 117/247 (47%), Gaps = 3/247 (1%) Frame = +1 Query: 124 PVTTLSNGAKIPVIGIGTWKSKPGEVT-QAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKT 300 P L+N ++P++G+GT++ + E T AV A+ GYR A VY NE +G A++ Sbjct: 6 PSVLLNNDIQMPLLGLGTFRLQGQEDTYSAVDAALKAGYRAFDTAAVYRNEAHLGHALRC 65 Query: 301 KIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWP--QAYKED 474 + + + RED+FITSKL + R + SL L + Y+DLYLIHWP Q Sbjct: 66 LLPKHGLSREDVFITSKL-GPKDQGSKARNGCQKSLEQLGLGYIDLYLIHWPGTQGLPVG 124 Query: 475 DAIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPG 654 D P + +W+ LE G R++GVSN+ + +Q +L + V Sbjct: 125 DKRNPENR-----------AQSWRVLEEFYSEGKFRAIGVSNYTVEHMQELLKSCKVP-- 171 Query: 655 H*PGRMPSVFKPXAIEAVLRRP*YYDNGVLPRWGXPDRPWAKPGDPHLMEDPKLKEIADR 834 P + F P ++ LR G+ G + ++ G L+ +P + EIA Sbjct: 172 --PAVLQVEFHPKLLQNDLR-------GLCKIRGVCFQAYSSLGTGLLLSNPVVLEIAKE 222 Query: 835 LGKXAAQ 855 G+ AQ Sbjct: 223 CGRTPAQ 229 >UniRef50_A1UEC5 Cluster: 2,5-didehydrogluconate reductase; n=20; Corynebacterineae|Rep: 2,5-didehydrogluconate reductase - Mycobacterium sp. (strain KMS) Length = 283 Score = 100 bits (239), Expect = 1e-19 Identities = 61/177 (34%), Positives = 90/177 (50%) Frame = +1 Query: 121 VPVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKT 300 +P +L++G IPV+G+G + E ++V A++ GYR I A VYGNE VG A+ Sbjct: 11 IPSVSLNDGHSIPVLGLGVGELSEAEAERSVAAALEAGYRLIDTAAVYGNEAAVGRAVNA 70 Query: 301 KIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDA 480 + RE++++T+KL + A SL L +DY+DLYLIHW Sbjct: 71 ----SGIPREEIYVTTKLAVADQGFGTSQDAARASLERLGLDYVDLYLIHW--------- 117 Query: 481 IFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKP 651 P GK Y+D+W L G+ RS+GV NFN++ L I+D + P Sbjct: 118 --PAGDHGK-------YIDSWGGLMKAKQDGVARSIGVCNFNAEHLSNIIDLSFFTP 165 >UniRef50_A5BF24 Cluster: Putative uncharacterized protein; n=1; Vitis vinifera|Rep: Putative uncharacterized protein - Vitis vinifera (Grape) Length = 212 Score = 100 bits (239), Expect = 1e-19 Identities = 64/179 (35%), Positives = 98/179 (54%), Gaps = 4/179 (2%) Frame = +1 Query: 127 VTTLSNGAKIPVIGIGT--WKSKPGE-VTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIK 297 +T S G IP++G+ T + P E + ++ AI++GYRH C Y +EK +GEAIK Sbjct: 1 MTLGSTGKAIPLVGMVTTVYPFAPSETMIDSILTAIELGYRHFDCVAAYLSEKPLGEAIK 60 Query: 298 TKIQEGVVK-REDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKED 474 ++ G++K R++LFIT + AL NL +DYLDLYLIHW + K Sbjct: 61 KAVKLGLIKSRDELFITLQ-------------AL-----NLQLDYLDLYLIHWSVSLKPG 102 Query: 475 DAIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKP 651 + P + D + +D WKA+E L +++GVSNF+ +L+ +L AS+ P Sbjct: 103 NYELPVNKDDHLP---IDLGSVWKAMEDFQKLSLTKAIGVSNFSCNKLEELLQTASILP 158 >UniRef50_A3UJS6 Cluster: Oxidoreductase; n=3; Alphaproteobacteria|Rep: Oxidoreductase - Oceanicaulis alexandrii HTCC2633 Length = 275 Score = 99 bits (238), Expect = 2e-19 Identities = 60/157 (38%), Positives = 84/157 (53%) Frame = +1 Query: 133 TLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQE 312 T +NGA IP +G GTW+ + + + V A+ GYRHI A +YGNE VG+ K Q Sbjct: 5 TQANGADIPKLGFGTWQLEDEDAARGVATALKTGYRHIDTAQIYGNEAAVGDGWK---QS 61 Query: 313 GVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPT 492 G VKRED F+T+K+W R ++ +++ SL L DY+DL L+HWP Sbjct: 62 G-VKREDFFLTTKVWRDKFRDGDLQASVKESLDKLKTDYVDLLLLHWP------------ 108 Query: 493 DADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNF 603 +V +T KA+ + G VR +GVSNF Sbjct: 109 -------VPEVPIAETMKAMNEVKEAGQVRHIGVSNF 138 >UniRef50_Q6CEJ0 Cluster: Yarrowia lipolytica chromosome B of strain CLIB122 of Yarrowia lipolytica; n=1; Yarrowia lipolytica|Rep: Yarrowia lipolytica chromosome B of strain CLIB122 of Yarrowia lipolytica - Yarrowia lipolytica (Candida lipolytica) Length = 302 Score = 99 bits (238), Expect = 2e-19 Identities = 70/186 (37%), Positives = 95/186 (51%), Gaps = 8/186 (4%) Frame = +1 Query: 118 SVPVTTLSNGAKIPVIGIGT---WKSKPGE-----VTQAVKDAIDIGYRHIXCAFVYGNE 273 +VP LSNG +IP IG G+ WK PGE + AV AI+ G+ HI A YG E Sbjct: 2 TVPKVKLSNGLEIPAIGFGSGTKWKRPPGEKEERELIDAVVSAINAGHLHIDTAEFYGTE 61 Query: 274 KEVGEAIKTKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHW 453 K++GEAIK E V R+D+F+TSK D + ++ L+ L DY DL+LIH Sbjct: 62 KQIGEAIK----ESGVPRKDIFLTSKTLFGLLADDPIE-SISNQLKTLQTDYFDLFLIHV 116 Query: 454 PQAYKEDDAIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILD 633 P DD + D W LE L GL +++GVSN + +L+ I+ Sbjct: 117 P---PNDDI-------------NYDLAKAWGVLEQLYEKGLAKAIGVSNHSPAELETIIK 160 Query: 634 NASVKP 651 A +KP Sbjct: 161 VAKIKP 166 >UniRef50_Q7VHE1 Cluster: Putative uncharacterized protein; n=1; Helicobacter hepaticus|Rep: Putative uncharacterized protein - Helicobacter hepaticus Length = 270 Score = 99.1 bits (236), Expect = 3e-19 Identities = 70/241 (29%), Positives = 118/241 (48%) Frame = +1 Query: 133 TLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQE 312 TL+NG K+P++G+GT+ +A+ +AI++GYR A +Y NE E+G AI ++ Sbjct: 5 TLNNGVKMPILGLGTYSLTGKAGQKAMSEAIEVGYRLFDSAQMYNNEAELGAAINAAVKG 64 Query: 313 GVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPT 492 G +KRE+ FI +KL + DL + ++E SL+ L +DY+D LIH P Y + A++ Sbjct: 65 G-IKREEFFIQTKLLES-SSEDLAKKSIEKSLKTLGLDYIDSLLIHMP--YSQSKAMY-- 118 Query: 493 DADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPGH*PGRM 672 +A+E G++R +G+SNF +K + + V P Sbjct: 119 -----------------RAMESFYKQGILRVIGISNFGAKAYSEFVKSCEVIPAINQCET 161 Query: 673 PSVFKPXAIEAVLRRP*YYDNGVLPRWGXPDRPWAKPGDPHLMEDPKLKEIADRLGKXAA 852 + + + ++ +L W P+ G ++E+P LK IA + K A Sbjct: 162 HLLLQQKPLREAMKS----KKTLLQSWS----PFI-AGKGSILENPTLKSIAQKYNKTPA 212 Query: 853 Q 855 Q Sbjct: 213 Q 213 >UniRef50_Q0SFM4 Cluster: Probable 2,5-didehydrogluconate reductase; n=1; Rhodococcus sp. RHA1|Rep: Probable 2,5-didehydrogluconate reductase - Rhodococcus sp. (strain RHA1) Length = 265 Score = 99.1 bits (236), Expect = 3e-19 Identities = 78/234 (33%), Positives = 113/234 (48%) Frame = +1 Query: 154 IPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQEGVVKRED 333 IP +G+GTW + T+AV I+ GYR I A +Y NE VG A+ E V RE+ Sbjct: 4 IPPLGLGTWPLTGPDATRAVLSGIEAGYRLIDTATIYDNEDAVGVALA----ECGVPREE 59 Query: 334 LFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTDADGKIQ 513 LF+T+KL + H +RGA+E SL+NL +D LDL+LIHWP Sbjct: 60 LFVTTKLRGSDHVSGDIRGAVERSLKNLGLDRLDLFLIHWPLPRHN-------------- 105 Query: 514 FSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPGH*PGRMPSVFKPX 693 YV ++A+ GLVR +GVSNF L+R++ G P+V + Sbjct: 106 ----RYVAAFEAMLACRDAGLVRHVGVSNFLETHLRRVVAET--------GESPAVNQIQ 153 Query: 694 AIEAVLRRP*YYDNGVLPRWGXPDRPWAKPGDPHLMEDPKLKEIADRLGKXAAQ 855 ++ R P + L G + W+ G ++ P + +IA RL + AQ Sbjct: 154 MDPSLARLPVRRADDEL---GVSTQSWSPLGRGEVLGSPVVTDIARRLDRTPAQ 204 >UniRef50_A6RMS0 Cluster: Putative uncharacterized protein; n=1; Botryotinia fuckeliana B05.10|Rep: Putative uncharacterized protein - Botryotinia fuckeliana B05.10 Length = 286 Score = 97.9 bits (233), Expect = 6e-19 Identities = 79/243 (32%), Positives = 119/243 (48%), Gaps = 3/243 (1%) Frame = +1 Query: 136 LSNGAKIPVIGIGTWKSKPG--EVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQ 309 L NG+ +P IG+GT++ G +V VK AI GYRHI A YGNE+ +G+AIK Sbjct: 10 LVNGSTLPAIGLGTFQGDDGNEKVKNIVKAAIQAGYRHIDGAAAYGNEEAIGDAIK---- 65 Query: 310 EGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFP 489 E + R++L ++ W H P V AL++SL L ++Y+ P AY P Sbjct: 66 ESGISRDEL---AQPW---HEPKDVERALDLSLEALGLEYV-------PHAYLPG----P 108 Query: 490 TDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPGH*PGR 669 + D + Y +TW+A+E LV G +++G+SNFN + +RIL+ A ++P Sbjct: 109 NNVDYE---RSRKYTETWQAMEKLVDSGKAKAIGLSNFNILKTKRILEIARIRPAVNQVE 165 Query: 670 MPSVFKPXAIEAVLRRP*YYDNGVLPRWGXPDRPWAKPGD-PHLMEDPKLKEIADRLGKX 846 F + A + + P G P A D P + D K+ +IA + G Sbjct: 166 AHPYFPQHELLAFCEKEHIHLMAHQPLGGKPVGVVAPHADIPGPLFDTKIAQIAAQTGMT 225 Query: 847 AAQ 855 AQ Sbjct: 226 PAQ 228 >UniRef50_Q4WP69 Cluster: Aldehyde reductase, putative; n=1; Aspergillus fumigatus|Rep: Aldehyde reductase, putative - Aspergillus fumigatus (Sartorya fumigata) Length = 350 Score = 97.5 bits (232), Expect = 9e-19 Identities = 62/148 (41%), Positives = 84/148 (56%), Gaps = 7/148 (4%) Frame = +1 Query: 229 IGYRHIXCAFVYGNEKEVGEAIKTKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSL 408 +GYRHI A V NE EVG K K+ V RE +F+TSKLWNT H P V AL+ ++ Sbjct: 72 VGYRHIDSAAVGLNEAEVGRGWK-KLG---VPREGIFLTSKLWNTHHHPSHVEEALDKTV 127 Query: 409 RNLNIDYLDLYLI----HWPQAYKEDDAIFPTDADGKIQFS--DVDYVDTWKALEPLVCH 570 ++L +YLDLYL+ H Y+ P G +F D+ DTW A E LV Sbjct: 128 KDLQTNYLDLYLLYPLGHILHTYQRH---IPASRPGHKRFRLVDIPIGDTWAAREKLVNA 184 Query: 571 GLVRSLGVSN-FNSKQLQRILDNASVKP 651 G +RSLGVSN F ++++ +L+ A + P Sbjct: 185 GKIRSLGVSNLFTIEKMEELLNTADIPP 212 >UniRef50_Q0CK00 Cluster: Predicted protein; n=1; Aspergillus terreus NIH2624|Rep: Predicted protein - Aspergillus terreus (strain NIH 2624) Length = 292 Score = 97.5 bits (232), Expect = 9e-19 Identities = 69/185 (37%), Positives = 96/185 (51%), Gaps = 9/185 (4%) Frame = +1 Query: 124 PVTTLSNGAKIPVIGIGT----WKSKPGEVT-----QAVKDAIDIGYRHIXCAFVYGNEK 276 P +L +G +P++G GT +K P + T + +K A++ G+ HI A YG E+ Sbjct: 4 PALSLKDGNLVPILGFGTGTAWYKDDPNDPTNPELIEVLKAALEKGFHHIDAADSYGTER 63 Query: 277 EVGEAIKTKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWP 456 EVG AI+ E + RE LFIT+K+ + V GAL+ SL L +DY+DLYL+H P Sbjct: 64 EVGIAIR----ESGIPREQLFITTKVLEGWKD---VPGALDASLERLQLDYVDLYLLHNP 116 Query: 457 QAYKEDDAIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDN 636 + P D IQ WK LE + G RS+GVSNF L+ IL+ Sbjct: 117 Y-------VIPNLTD--IQ-------SAWKGLEAVKATGKARSIGVSNFQRNHLEAILET 160 Query: 637 ASVKP 651 SV P Sbjct: 161 CSVVP 165 >UniRef50_Q8G7K9 Cluster: Dehydrogenase or reductase protein; n=4; Bifidobacterium|Rep: Dehydrogenase or reductase protein - Bifidobacterium longum Length = 289 Score = 97.1 bits (231), Expect = 1e-18 Identities = 60/178 (33%), Positives = 86/178 (48%) Frame = +1 Query: 118 SVPVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIK 297 +VP L +G IP +G+G + V V+ A++ GYRHI A Y NE VG A+ Sbjct: 10 NVPDIALKDGHSIPQVGLGVLRIDDEGVVPVVESALEAGYRHIDGAAGYNNEAGVGRALA 69 Query: 298 TKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDD 477 KRE L++T+KL ++ D A + SL+ L +DY+D+Y+IHWP + Sbjct: 70 ASGYNKGAKRETLWVTTKLRDSQQGYDSALKAFDNSLKLLQLDYVDMYMIHWPTPF---- 125 Query: 478 AIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKP 651 D DTWKA L G+ R+LGV NF L+R+ + P Sbjct: 126 --------------DWRSTDTWKAFVKLRDEGMARTLGVCNFMPADLKRLHEETGAWP 169 >UniRef50_A6VNW9 Cluster: Aldo/keto reductase precursor; n=1; Actinobacillus succinogenes 130Z|Rep: Aldo/keto reductase precursor - Actinobacillus succinogenes 130Z Length = 315 Score = 97.1 bits (231), Expect = 1e-18 Identities = 68/240 (28%), Positives = 113/240 (47%) Frame = +1 Query: 136 LSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQEG 315 L+NG ++P+IGIG W P + ++V +A+ GYR I A +Y NE+ VG A++ + Sbjct: 47 LNNGIEMPIIGIGVWTLTPEQTEKSVGEALKAGYRLIDTARMYRNEQAVGRAVR----DS 102 Query: 316 VVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTD 495 + RE++FIT+K++ + + A+ LR L+ DY+DL L+H+P Sbjct: 103 GIPREEIFITTKIYGSGDYAN-AEAAINERLRLLDTDYIDLLLLHYP------------- 148 Query: 496 ADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPGH*PGRMP 675 D + WK +E V G +R++G+SN++ K RI+ A++ P + Sbjct: 149 --------DQNDTKAWKVMEQFVKAGKIRAIGLSNYHRKTFNRIMQAATITPAVVQNEVH 200 Query: 676 SVFKPXAIEAVLRRP*YYDNGVLPRWGXPDRPWAKPGDPHLMEDPKLKEIADRLGKXAAQ 855 + +A LR P G + G L DP + +A + K AQ Sbjct: 201 IYNQDKQTKAFLRNYGTQMEAWYPLGGR--NSYGNGGKDVLFADPTIVSLAKKYAKSPAQ 258 >UniRef50_Q89JN4 Cluster: Oxidoreductase; n=8; Rhizobiales|Rep: Oxidoreductase - Bradyrhizobium japonicum Length = 272 Score = 96.7 bits (230), Expect = 1e-18 Identities = 42/109 (38%), Positives = 70/109 (64%) Frame = +1 Query: 139 SNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQEGV 318 +NGA+IP IG+GTW+ + V+ A+ +GYRHI A VY NE+EVG+ ++ Sbjct: 6 ANGARIPAIGLGTWELSGRPCARVVEQALRLGYRHIDTAQVYDNEREVGDGVRA----SG 61 Query: 319 VKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAY 465 V+R+D+F+T+K+W P+ + +++ SL L + +DL L+HWP ++ Sbjct: 62 VRRDDVFLTTKVWTNHFAPNDLERSVKESLARLRLPSVDLLLLHWPNSH 110 Score = 37.5 bits (83), Expect = 0.97 Identities = 17/45 (37%), Positives = 26/45 (57%), Gaps = 2/45 (4%) Frame = +2 Query: 653 VTNQVECHPYLNXKRLKQFCEDRDIMITXYSP--XGXLPTDPGLS 781 V NQVE HPYL+ +++ C+ + + YSP G + TD L+ Sbjct: 154 VCNQVEFHPYLDQAKVRAACDQHGLALVAYSPIARGRIKTDQTLA 198 >UniRef50_A7RRF6 Cluster: Predicted protein; n=2; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 275 Score = 96.3 bits (229), Expect = 2e-18 Identities = 64/180 (35%), Positives = 93/180 (51%) Frame = +1 Query: 112 MTSVPVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEA 291 +T TLS+G KIP G+G + QAV A++ GYR I A Y NEK VGEA Sbjct: 1 LTLSSTRTLSDGYKIPRFGLGLYDLDEKHTKQAVLWALENGYRMIDTAASYNNEKRVGEA 60 Query: 292 IKTKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKE 471 ++ E V R ++++ +K+++T H + A + SL L +DY+DLYLIH Sbjct: 61 LR----ESAVPRSEVYLVTKVYHTDHGYEKTMKAYDRSLSALGVDYVDLYLIH------- 109 Query: 472 DDAIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKP 651 FP A V +W+A+ L GL RS+GVSNFN L+ + ++ + P Sbjct: 110 ----FPVPA---------GVVGSWEAMAELQGKGLTRSIGVSNFNIHHLEALQKHSVIPP 156 Score = 39.1 bits (87), Expect = 0.32 Identities = 16/32 (50%), Positives = 18/32 (56%) Frame = +2 Query: 653 VTNQVECHPYLNXKRLKQFCEDRDIMITXYSP 748 V NQ+E HPYL + L FC I I YSP Sbjct: 157 VVNQIEVHPYLQMEELVDFCRKHSIAIQAYSP 188 >UniRef50_Q6F7K7 Cluster: 2,5-diketo-D-gluconate reductase; n=20; Bacteria|Rep: 2,5-diketo-D-gluconate reductase - Acinetobacter sp. (strain ADP1) Length = 297 Score = 95.9 bits (228), Expect = 3e-18 Identities = 63/181 (34%), Positives = 90/181 (49%) Frame = +1 Query: 109 IMTSVPVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGE 288 I ++P L +G IP +G GT+ K + + A+ GYR + AF Y NE VG Sbjct: 18 IEKNIPDLILHDGHSIPALGFGTYTLKGQQGVDTMLRALGHGYRMLDSAFNYENEGAVGA 77 Query: 289 AIKTKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYK 468 A++ Q G++ R+++FITSKL H D +E SL + DYLDLYLIHWP + Sbjct: 78 AVR---QSGLL-RDEIFITSKLPGRHHAYDKAMETIEESLYRMQFDYLDLYLIHWPNPQQ 133 Query: 469 EDDAIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVK 648 G Y++ W+AL G +RS+GVSNF K ++ + V Sbjct: 134 -----------GL-------YIEAWQALIDAQKKGYIRSIGVSNFLPKHIETLRRETGVI 175 Query: 649 P 651 P Sbjct: 176 P 176 >UniRef50_Q9C1X5 Cluster: Xylose and arabinose reductase; n=1; Schizosaccharomyces pombe|Rep: Xylose and arabinose reductase - Schizosaccharomyces pombe (Fission yeast) Length = 283 Score = 95.9 bits (228), Expect = 3e-18 Identities = 68/171 (39%), Positives = 87/171 (50%) Frame = +1 Query: 115 TSVPVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAI 294 T TL+NG IP IG G + K E V A+D GYRHI A VYGNE G+AI Sbjct: 6 TESTTVTLTNGMVIPRIGFGAFMLKYNECYGLVTQALDSGYRHIDTAAVYGNEDICGKAI 65 Query: 295 KTKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKED 474 ++ VKR D+F+TSKL N R A+ SL +L Y+DL+LI P Sbjct: 66 VDWCEKNNVKRTDIFLTSKLANCSDYYS-TRAAIRSSLHHLG-TYIDLFLIQSP------ 117 Query: 475 DAIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRI 627 A GK + +WKA+E V G +RS+GVSN+ K LQ + Sbjct: 118 -------AGGK-----KSRIASWKAMEEFVDSGDIRSVGVSNYGVKHLQEL 156 Score = 36.7 bits (81), Expect = 1.7 Identities = 13/30 (43%), Positives = 20/30 (66%) Frame = +2 Query: 659 NQVECHPYLNXKRLKQFCEDRDIMITXYSP 748 NQ+E HP+L+ + ++C+ DI I YSP Sbjct: 168 NQIELHPFLSQDDIVKYCQSHDIAIEAYSP 197 >UniRef50_Q2U219 Cluster: Aldo/keto reductase family proteins; n=6; Pezizomycotina|Rep: Aldo/keto reductase family proteins - Aspergillus oryzae Length = 294 Score = 95.9 bits (228), Expect = 3e-18 Identities = 64/187 (34%), Positives = 99/187 (52%), Gaps = 9/187 (4%) Frame = +1 Query: 118 SVPVTTLSNGAKIPVIGIGT---WKSKPG------EVTQAVKDAIDIGYRHIXCAFVYGN 270 + P L++ IP++G GT W + G E+ +A+K AI +GYRH+ A VYG Sbjct: 8 NTPRVKLNDNVSIPILGYGTGTAWYKQAGDDSVNRELVEAIKTAIRLGYRHLDGAEVYGT 67 Query: 271 EKEVGEAIKTKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIH 450 E E+G AIK E + RE+LF+T+K+ + A++ SLR L ++Y+DLYLIH Sbjct: 68 EAELGVAIK----ESGIPREELFVTTKVITNIAD---IPSAIDQSLRKLQLNYVDLYLIH 120 Query: 451 WPQAYKEDDAIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRIL 630 P F +DG++Q W A+E + G +++GVSN++ L+ L Sbjct: 121 SP---------FFAKSDGELQ-------QAWAAMEKVQQAGKAKAIGVSNYHQSHLEATL 164 Query: 631 DNASVKP 651 A + P Sbjct: 165 KTAVIAP 171 Score = 38.7 bits (86), Expect = 0.42 Identities = 17/41 (41%), Positives = 23/41 (56%) Frame = +2 Query: 653 VTNQVECHPYLNXKRLKQFCEDRDIMITXYSPXGXLPTDPG 775 V NQ+E HPYL + L +F ++DI I Y P + PG Sbjct: 172 VINQIEHHPYLQQEELLRFQREKDIKIASYGPLTPILRAPG 212 >UniRef50_Q15NA5 Cluster: Aldo/keto reductase; n=2; Gammaproteobacteria|Rep: Aldo/keto reductase - Pseudoalteromonas atlantica (strain T6c / BAA-1087) Length = 273 Score = 95.5 bits (227), Expect = 3e-18 Identities = 60/159 (37%), Positives = 83/159 (52%) Frame = +1 Query: 154 IPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQEGVVKRED 333 IP G GT++ K + AV++A+D+GYRHI A Y NE EVG+AI + R + Sbjct: 11 IPTPGFGTYRLKGDDAKLAVENALDVGYRHIDTAQAYENEAEVGDAISA----SKISRGE 66 Query: 334 LFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTDADGKIQ 513 LF+T+K+W D +++ SL LN DY+DL L+HWP D K+ Sbjct: 67 LFVTTKVWFDNLSADKFITSVQNSLTQLNTDYVDLLLVHWP------------SPDNKV- 113 Query: 514 FSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRIL 630 S +Y+ KA + GL R +GVSNF QL L Sbjct: 114 -SMAEYLKELKACKE---RGLTRHIGVSNFTQSQLDEAL 148 Score = 37.9 bits (84), Expect = 0.73 Identities = 14/34 (41%), Positives = 20/34 (58%) Frame = +2 Query: 653 VTNQVECHPYLNXKRLKQFCEDRDIMITXYSPXG 754 +TNQ+E HP K L +C+ +I +T Y P G Sbjct: 157 LTNQIEVHPNFQNKELVAYCQRNNIQVTAYMPLG 190 >UniRef50_Q8Y463 Cluster: Lmo2592 protein; n=40; Bacteria|Rep: Lmo2592 protein - Listeria monocytogenes Length = 283 Score = 95.1 bits (226), Expect = 5e-18 Identities = 78/241 (32%), Positives = 117/241 (48%), Gaps = 1/241 (0%) Frame = +1 Query: 136 LSNGAKIPVIGIGTWK-SKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQE 312 L+NG ++P++G GT++ + E AVKDAI GYRHI A Y NE+ VG I Sbjct: 6 LNNGVEVPILGFGTYQITDAAEAEHAVKDAIKAGYRHIDTAQSYMNEEAVGRGIAA---- 61 Query: 313 GVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPT 492 V R++LFIT+K+W V + + SL+ L +DY+DL LIH P Sbjct: 62 SGVDRKELFITTKIWVENVSYKGVMSSFDRSLKRLGLDYVDLLLIHQP------------ 109 Query: 493 DADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPGH*PGRM 672 F+DV W A+E L G +R++GVSNF+ ++ + V P + Sbjct: 110 -------FNDV--YGAWIAMEELQASGKIRAIGVSNFSPDRVIDLAAFNEVTPQVNQIEV 160 Query: 673 PSVFKPXAIEAVLRRP*YYDNGVLPRWGXPDRPWAKPGDPHLMEDPKLKEIADRLGKXAA 852 + A A+LR+ + + W P+A+ G + +P L +I + GK AA Sbjct: 161 NPFQQQTANLAILRK----EGVAIEAWA----PFAE-GKNDIFNNPVLTKIGAKYGKSAA 211 Query: 853 Q 855 Q Sbjct: 212 Q 212 >UniRef50_Q8EUH6 Cluster: Oxidoreductase; n=1; Mycoplasma penetrans|Rep: Oxidoreductase - Mycoplasma penetrans Length = 285 Score = 94.7 bits (225), Expect = 6e-18 Identities = 62/173 (35%), Positives = 92/173 (53%), Gaps = 1/173 (0%) Frame = +1 Query: 136 LSNGAKIPVIGIGTWKSKPGEVTQAVKDAID-IGYRHIXCAFVYGNEKEVGEAIKTKIQE 312 L+NG +P+IG+G +K++ + AID GYR I A VY NE+ VG AIK + Sbjct: 6 LANGLHMPIIGLGVYKAEGENCENTIIKAIDDYGYRMIDTAQVYFNEEFVGNAIK----Q 61 Query: 313 GVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPT 492 +KRED+FIT+K+W + + + ++ SL+ L +Y+DL L+H P Sbjct: 62 TKIKREDIFITTKVWISNYGYNNTMYSISKSLKKLQTNYIDLVLLHQPFG---------- 111 Query: 493 DADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKP 651 DY WKALE L G+V+++GVSNF + +L + VKP Sbjct: 112 -----------DYYSAWKALEVLYKKGIVKAIGVSNFEADRLVDFCLHVDVKP 153 >UniRef50_A4YQ04 Cluster: 2,5-diketo-D-gluconate reductase B; n=15; Proteobacteria|Rep: 2,5-diketo-D-gluconate reductase B - Bradyrhizobium sp. (strain ORS278) Length = 273 Score = 94.7 bits (225), Expect = 6e-18 Identities = 42/106 (39%), Positives = 66/106 (62%) Frame = +1 Query: 139 SNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQEGV 318 + G ++P +G+GT++ + AV+ A+ +GYRHI A +Y NE +G A+ Sbjct: 6 TQGVRLPKLGLGTFRMQGTVCRDAVESALALGYRHIDTAEMYANEDAIGAALAA----AQ 61 Query: 319 VKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWP 456 + REDL +T+K+W PD +R A + SL+ L +D++DLYLIHWP Sbjct: 62 IAREDLHVTTKVWPENLAPDAIRRAFDTSLKKLRLDFVDLYLIHWP 107 >UniRef50_Q1DLF1 Cluster: Putative uncharacterized protein; n=1; Coccidioides immitis|Rep: Putative uncharacterized protein - Coccidioides immitis Length = 324 Score = 94.7 bits (225), Expect = 6e-18 Identities = 65/177 (36%), Positives = 94/177 (53%), Gaps = 10/177 (5%) Frame = +1 Query: 151 KIPVIGIGTWKSKP-----GEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQEG 315 +IP G+GT++ P G V +V A+ IGYRHI A YG V I I+ Sbjct: 15 RIPARGLGTFQVDPSLYPEGSVKDSVLHALKIGYRHIDAALAYG-WGSVERGIGAAIRAS 73 Query: 316 VVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAY-KEDDAIFPT 492 V RED+F+ +KL N FH P+ V + +SL+NL + Y+ P AY K ++ Sbjct: 74 GVPREDVFVVTKLHNCFHAPEDVEVGMNMSLKNLGLGYV-------PYAYTKGENYSTVR 126 Query: 493 DADGK----IQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKP 651 DGK I+ S + TWKA+E LV G + +GVSNF++ +L+R+L + P Sbjct: 127 KPDGKPVVDIELSRA-FDTTWKAMENLVDQGKAKLIGVSNFSTPKLKRLLSVCRIFP 182 Score = 42.7 bits (96), Expect = 0.026 Identities = 17/37 (45%), Positives = 23/37 (62%) Frame = +2 Query: 653 VTNQVECHPYLNXKRLKQFCEDRDIMITXYSPXGXLP 763 V NQVE +PY K+L +FC + +I +T Y P G P Sbjct: 183 VVNQVELNPYFPQKQLLRFCHEHEIHVTAYGPLGCTP 219 >UniRef50_A7D761 Cluster: Aldo/keto reductase; n=2; Halobacteriaceae|Rep: Aldo/keto reductase - Halorubrum lacusprofundi ATCC 49239 Length = 665 Score = 94.3 bits (224), Expect = 8e-18 Identities = 56/185 (30%), Positives = 85/185 (45%), Gaps = 18/185 (9%) Frame = +1 Query: 151 KIPVIGIGTWKSKPGEVTQAVKD---AIDIGYRHIXCAFVYGNEKEVGEAIKTKIQEGVV 321 ++P +G G + + GE V A+D GYR + A +YGNE +GE + G Sbjct: 375 RLPAVGFGCSRYRDGEYVDRVDSIATALDAGYRLLDSAELYGNEHRIGELLAAP---GAP 431 Query: 322 KREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAY------------ 465 RE +F+ K W T HR + + A S L ID D Y +HWP A Sbjct: 432 DRERVFLLGKAWRTNHRREHLLAACAGSREELGIDAFDCYALHWPSALEHRGELNRLAEK 491 Query: 466 ---KEDDAIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDN 636 +++ FP DG+ +DV W+ LE + G R+LG+ N + QL+ +L+ Sbjct: 492 PVERQETLTFPEGEDGEPATADVALATAWRNLEAVHERGWARTLGICNVSRAQLETVLET 551 Query: 637 ASVKP 651 + P Sbjct: 552 GEIDP 556 >UniRef50_A3JU52 Cluster: 2,5-diketo-D-gluconic acid reductase A; n=1; Rhodobacterales bacterium HTCC2150|Rep: 2,5-diketo-D-gluconic acid reductase A - Rhodobacterales bacterium HTCC2150 Length = 334 Score = 93.9 bits (223), Expect = 1e-17 Identities = 66/180 (36%), Positives = 87/180 (48%), Gaps = 8/180 (4%) Frame = +1 Query: 112 MTSVPVT-TLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGE 288 MT+ T TL+ IP +G GT+ + + AI GYRHI A Y NEK VG Sbjct: 33 MTNTATTFTLNTTTTIPAVGFGTYLISNDDAKSTISAAIQAGYRHIDTASGYQNEKTVGA 92 Query: 289 AIKTKIQEGVVKREDLFITSKLW--NTF--HRPDLVRGAL---EVSLRNLNIDYLDLYLI 447 IK +Q + R+DLF+T+KLW N P L + SL L +DY+DLYLI Sbjct: 93 GIKAGLQSAGITRKDLFVTAKLWPGNPAWGDAPKTKAQTLDECDASLARLGLDYVDLYLI 152 Query: 448 HWPQAYKEDDAIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRI 627 H P G ++ ++ W+AL L +G RS+GVSNFN L I Sbjct: 153 HAPYG-------------GDMR------LEQWRALLELQANGKARSIGVSNFNESHLNEI 193 >UniRef50_Q5UX52 Cluster: Oxidoreductase aldo/keto reductase family; n=1; Haloarcula marismortui|Rep: Oxidoreductase aldo/keto reductase family - Haloarcula marismortui (Halobacterium marismortui) Length = 274 Score = 93.9 bits (223), Expect = 1e-17 Identities = 61/166 (36%), Positives = 83/166 (50%) Frame = +1 Query: 145 GAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQEGVVK 324 G +P +G+GTW+ + V+ A+ +GYRHI A YGNE++VG + V Sbjct: 8 GTSVPALGLGTWQLTGQSCRETVETALGMGYRHIDTAQAYGNERQVG----LGMDAAAVD 63 Query: 325 REDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTDADG 504 RED+F+T+KL + VR + SL L DYLDL LIHWP P A Sbjct: 64 REDVFLTTKLDGSNRDERSVRRSTRESLNKLGTDYLDLLLIHWPNT--------PWMA-- 113 Query: 505 KIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNAS 642 +T A+ +V GLVR +GVSNF+ L R D +S Sbjct: 114 -------SLSETLGAMNDVVEEGLVRHIGVSNFSPSLLDRARDISS 152 Score = 40.3 bits (90), Expect = 0.14 Identities = 17/43 (39%), Positives = 27/43 (62%), Gaps = 2/43 (4%) Frame = +2 Query: 656 TNQVECHPYLNXKRLKQFCEDRDIMITXYSP--XGXLPTDPGL 778 T+QV+ HPY + ++L +C D+++T YSP G + DP L Sbjct: 157 TDQVQYHPYWDQRKLLDYCRIHDVLLTAYSPLARGGVLDDPAL 199 >UniRef50_Q5B034 Cluster: Putative uncharacterized protein; n=1; Emericella nidulans|Rep: Putative uncharacterized protein - Emericella nidulans (Aspergillus nidulans) Length = 186 Score = 93.5 bits (222), Expect = 1e-17 Identities = 61/166 (36%), Positives = 91/166 (54%), Gaps = 1/166 (0%) Frame = +1 Query: 136 LSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQEG 315 L+ GA IP +G+GTWKS+PGEV +A+ A+ GYRHI A +G Sbjct: 9 LNPGALIPAVGLGTWKSEPGEVARALAHALKTGYRHIDAA--------LG---------- 50 Query: 316 VVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTD 495 V RE++FITSKLWNT H+P++ G L+ +L L +D LDL Y E + P + Sbjct: 51 -VPREEIFITSKLWNT-HQPNIKEG-LQKTLDALGVDCLDL--------YNETSDLLPVN 99 Query: 496 ADG-KIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRIL 630 DG + D +TW+ +E G +++GV+N++ L+ +L Sbjct: 100 PDGTRAVDRSWDQSETWRQMEDFYKSGKAKAIGVANWSIPYLEELL 145 >UniRef50_Q4PE96 Cluster: Putative uncharacterized protein; n=1; Ustilago maydis|Rep: Putative uncharacterized protein - Ustilago maydis (Smut fungus) Length = 293 Score = 93.1 bits (221), Expect = 2e-17 Identities = 64/170 (37%), Positives = 88/170 (51%), Gaps = 2/170 (1%) Frame = +1 Query: 133 TLSNGAKIPVIGIGTWKSKPGEVTQAVKDAID-IGYRHIXCAFVYGNEKEVGEAIKTKIQ 309 T+ +G +P GIG W + E QA+ +A D GYRH+ A Y NE + GEA++ Sbjct: 20 TMVDGYAMPRFGIGAWDMRGSECKQALLNAFDKAGYRHVDTARYYRNEADCGEAVR---- 75 Query: 310 EGVVKREDLFITSKLW-NTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIF 486 E V R +LF T+K++ N R A+E SL +DYLDL L+H P Sbjct: 76 ECSVPRSELFYTTKVYLNEMGGGSKTRLAVEDSLAKAGLDYLDLVLLHAP---------- 125 Query: 487 PTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDN 636 DG +F +D+W L LV G VRSLGVSNF +Q ++D+ Sbjct: 126 ----DGGKKFR----LDSWDTLTELVQEGKVRSLGVSNFGPHHIQELIDS 167 >UniRef50_Q5FK99 Cluster: Oxidoreductase aldo-keto reductase family; n=5; Lactobacillus|Rep: Oxidoreductase aldo-keto reductase family - Lactobacillus acidophilus Length = 289 Score = 92.7 bits (220), Expect = 2e-17 Identities = 64/181 (35%), Positives = 92/181 (50%), Gaps = 1/181 (0%) Frame = +1 Query: 112 MTSVPVTTLSNGAKIPVIGIGTWK-SKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGE 288 MT +P L++G +IP +G G ++ S E +AV+ AI GYR I A Y N+ VGE Sbjct: 1 MTDIPKIKLNDGNEIPQLGFGVFQISNHDEAVKAVESAISNGYRLIDTAEAYNNQTAVGE 60 Query: 289 AIKTKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYK 468 AIK V R+D+F+T+KLW + + A++ L+ L DY+D+ L+H QAY Sbjct: 61 AIKNSD----VNRDDIFLTTKLWVSNFTYEKASKAIDEDLKELGTDYIDMMLLH--QAYG 114 Query: 469 EDDAIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVK 648 D W+ALE G +S+GVSNF QL + ++VK Sbjct: 115 -------------------DVAGAWRALEDAQKAGKTKSIGVSNFWPDQLMNLQLMSNVK 155 Query: 649 P 651 P Sbjct: 156 P 156 >UniRef50_Q927P9 Cluster: Lin2739 protein; n=12; Bacteria|Rep: Lin2739 protein - Listeria innocua Length = 283 Score = 92.3 bits (219), Expect = 3e-17 Identities = 62/170 (36%), Positives = 92/170 (54%), Gaps = 1/170 (0%) Frame = +1 Query: 136 LSNGAKIPVIGIGTWK-SKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQE 312 L+NG ++P++G GT++ + GE QAVK+AI GYRHI A Y NE+ VG I Sbjct: 6 LNNGIEVPILGFGTYQITDAGEAEQAVKEAIAAGYRHIDTAQSYMNEEAVGRGIAA---- 61 Query: 313 GVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPT 492 V R++LFIT+K+W V + + SL+ L +DY+DL LIH P Sbjct: 62 SGVDRKELFITTKIWVENVSYKGVMSSFDRSLKRLGLDYIDLLLIHQP------------ 109 Query: 493 DADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNAS 642 ++DV W A+E L G ++++GVSNF + R++D A+ Sbjct: 110 -------YNDV--YGAWMAMEELQAQGKIKAIGVSNFG---VDRVVDLAA 147 >UniRef50_Q14LU6 Cluster: Putative aldo/keto reductase oxidoreductase protein; n=1; Spiroplasma citri|Rep: Putative aldo/keto reductase oxidoreductase protein - Spiroplasma citri Length = 138 Score = 92.3 bits (219), Expect = 3e-17 Identities = 47/105 (44%), Positives = 70/105 (66%), Gaps = 1/105 (0%) Frame = +1 Query: 136 LSNGAKIPVIGIGTWK-SKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQE 312 L NG +IP+IG+GT+K + EV QA+ A+ GYRHI A +YGNE+ +G+AIK + Sbjct: 10 LFNGVEIPLIGLGTYKMTDEHEVYQAIITALQNGYRHIDTAQIYGNEELIGKAIK----D 65 Query: 313 GVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLI 447 V R+++F+TSK+WN H+ D ++ L+ L+ DYLDL L+ Sbjct: 66 SGVPRKEIFLTSKIWNANHKYDAALQEIDNILKRLDTDYLDLCLV 110 >UniRef50_Q1Q8W8 Cluster: Aldo/keto reductase; n=1; Psychrobacter cryohalolentis K5|Rep: Aldo/keto reductase - Psychrobacter cryohalolentis (strain K5) Length = 282 Score = 91.9 bits (218), Expect = 4e-17 Identities = 60/155 (38%), Positives = 84/155 (54%), Gaps = 2/155 (1%) Frame = +1 Query: 148 AKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQEGVVKR 327 A IPV+G+GTW+S + V + +GY HI A YGNE EVG+ IK Q GV R Sbjct: 14 ANIPVLGLGTWQSTGQDCIDVVSQGLRMGYEHIDTAQAYGNEVEVGKGIK---QSGVA-R 69 Query: 328 EDLFITSKLW--NTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTDAD 501 + F+T+K++ + P+ + A + SL NL+ DY+DL L+HWP D Sbjct: 70 DKFFLTTKIFPDDMKFEPEKLVAAAKRSLENLDTDYVDLLLLHWP--------------D 115 Query: 502 GKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFN 606 ++ S +T AL L GL R++GVSNFN Sbjct: 116 DRVPLS-----ETIPALCELQKQGLTRNIGVSNFN 145 Score = 35.5 bits (78), Expect = 3.9 Identities = 14/32 (43%), Positives = 20/32 (62%) Frame = +2 Query: 653 VTNQVECHPYLNXKRLKQFCEDRDIMITXYSP 748 V NQVE HP++ K L+ F + I++ YSP Sbjct: 161 VVNQVEFHPFIKQKTLQTFLNNHHILLEAYSP 192 >UniRef50_A5DRJ6 Cluster: Putative uncharacterized protein; n=4; Pichia guilliermondii|Rep: Putative uncharacterized protein - Pichia guilliermondii (Yeast) (Candida guilliermondii) Length = 287 Score = 91.9 bits (218), Expect = 4e-17 Identities = 59/173 (34%), Positives = 92/173 (53%), Gaps = 2/173 (1%) Frame = +1 Query: 136 LSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKI-QE 312 L NG++IP G+G + + V+ A+D+GYR I A Y NE+E GE IK + ++ Sbjct: 12 LLNGSRIPACGVGVYLLPASQTAGIVEKALDVGYRLIDTAQEYENERETGEGIKAWLGKD 71 Query: 313 GVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNL-NIDYLDLYLIHWPQAYKEDDAIFP 489 KRED+ T+K+ N D +L+ SL + +++Y+DL LIH P + K+ Sbjct: 72 KNNKREDVLYTTKITNLNQGYDRTWRSLKESLNKVKHLEYIDLVLIHDPLSDKK------ 125 Query: 490 TDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVK 648 ++TWKAL+ V G+V+S+GVSNF +Q + D +K Sbjct: 126 ------------TRIETWKALQEAVDSGMVKSIGVSNFGKHHIQELYDWEGLK 166 >UniRef50_A6SI80 Cluster: Putative uncharacterized protein; n=1; Botryotinia fuckeliana B05.10|Rep: Putative uncharacterized protein - Botryotinia fuckeliana B05.10 Length = 253 Score = 91.5 bits (217), Expect = 6e-17 Identities = 62/183 (33%), Positives = 90/183 (49%), Gaps = 7/183 (3%) Frame = +1 Query: 124 PVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTK 303 P L++G ++P +G G WK V +AI GYR Sbjct: 4 PTLKLNSGHEMPQVGFGLWKVDNATCADTVYNAIKTGYR--------------------- 42 Query: 304 IQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYK-EDDA 480 + +G DLFI SKLWN+FH D V L + IDY DL+++H+P A + D A Sbjct: 43 LFDGAC---DLFIVSKLWNSFHDGDRVGPITRKQLADWGIDYFDLFIVHFPVALRYVDPA 99 Query: 481 I-FP-----TDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNAS 642 + +P +D +G +Q S +TW+A+E LV GL +S+GVSNF L +L A Sbjct: 100 VRYPPGWQYSDKEGDVQQSKASIQETWQAMEKLVDEGLAKSIGVSNFQGALLIDLLRYAR 159 Query: 643 VKP 651 ++P Sbjct: 160 IRP 162 >UniRef50_Q09632 Cluster: Probable oxidoreductase ZK1290.5; n=2; Caenorhabditis|Rep: Probable oxidoreductase ZK1290.5 - Caenorhabditis elegans Length = 321 Score = 91.5 bits (217), Expect = 6e-17 Identities = 66/178 (37%), Positives = 94/178 (52%), Gaps = 1/178 (0%) Frame = +1 Query: 121 VPVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAID-IGYRHIXCAFVYGNEKEVGEAIK 297 +P T LSN ++P+IG+GT S G AV +I GYR I A YG EK++G A+K Sbjct: 2 IPTTVLSNNVEMPLIGLGTTHSG-GYYHDAVLHSIKKCGYRLIDTAKRYGVEKQLGIAVK 60 Query: 298 TKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDD 477 V RE++F+++KLW D V A + S L DYLD+Y+IH PQ D Sbjct: 61 NCS----VPREEMFLSTKLWPV-DCGDEVYNAFQTSCEKLQTDYLDMYMIHMPQL--PDW 113 Query: 478 AIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKP 651 + + K TW+ +E L VRS+GVSN++ + L +L+ AS+ P Sbjct: 114 IVNQKETKEK----------TWRQMELLYEDEHVRSIGVSNYSIEDLDELLEFASILP 161 >UniRef50_Q8EVT8 Cluster: Oxidoreductase-aldo/keto reductase family; n=1; Mycoplasma penetrans|Rep: Oxidoreductase-aldo/keto reductase family - Mycoplasma penetrans Length = 299 Score = 90.6 bits (215), Expect = 1e-16 Identities = 60/178 (33%), Positives = 96/178 (53%), Gaps = 2/178 (1%) Frame = +1 Query: 124 PVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTK 303 P+ TL++G +IP+IG+GT A+K A++IG R A +YGNEKEVGE I+ Sbjct: 35 PLLTLNDGYQIPIIGLGTTSLHNQTCKNAIKAALEIGIRLFDTASLYGNEKEVGETIR-- 92 Query: 304 IQEGVVKREDLFITSKLW--NTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDD 477 E + R ++F+ +KL+ F P+ A+E +L LN DY+D+ L+H P E+D Sbjct: 93 --ESNINRNEIFVITKLYPGAQFANPE---KAIEEALNKLNTDYIDMMLLHHP---GEND 144 Query: 478 AIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKP 651 V +KA+E + G ++S+G+SN+ K++ L ++KP Sbjct: 145 ------------------VKAYKAIEKYIEKGKIKSVGLSNWYIKEINSFLPQINIKP 184 >UniRef50_Q9X265 Cluster: Oxidoreductase, aldo/keto reductase family; n=2; Thermotoga|Rep: Oxidoreductase, aldo/keto reductase family - Thermotoga maritima Length = 274 Score = 90.2 bits (214), Expect = 1e-16 Identities = 62/177 (35%), Positives = 92/177 (51%), Gaps = 12/177 (6%) Frame = +1 Query: 145 GAKIPVIGIGTWK---------SKPGEVTQAVKDAIDIGYRHIXCAFVYGN---EKEVGE 288 G +IP +G+GTW S+ E+ + +K AI +GY HI A YG E+ +G+ Sbjct: 10 GEEIPALGLGTWGIGGFETPDYSRDEEMVELLKTAIKMGYTHIDTAEYYGGGHTEELIGK 69 Query: 289 AIKTKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYK 468 AIK +REDLFI SK+W T R D + +LE +L+ L+ DY+DLYLIHWP Sbjct: 70 AIKD------FRREDLFIVSKVWPTHLRRDDLLRSLENTLKRLDTDYVDLYLIHWPN--- 120 Query: 469 EDDAIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNA 639 ++ +T A+ V GL+R +GVSNF+ + L+ + + Sbjct: 121 ----------------PEIPLEETLSAMAEGVRQGLIRYIGVSNFDRRLLEEAISKS 161 >UniRef50_Q9HM42 Cluster: Alcohol dehydrogenase related protein; n=1; Thermoplasma acidophilum|Rep: Alcohol dehydrogenase related protein - Thermoplasma acidophilum Length = 284 Score = 90.2 bits (214), Expect = 1e-16 Identities = 58/164 (35%), Positives = 84/164 (51%), Gaps = 2/164 (1%) Frame = +1 Query: 145 GAKIPVIGIGTW--KSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQEGV 318 G K+ VIG+GTW + E ++++ A+D G I A +YG E VGEAIK Sbjct: 13 GRKVSVIGVGTWSLEGSRSENVRSIRYALDHGVNFIDTAEMYGTEDIVGEAIKG------ 66 Query: 319 VKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTDA 498 +REDLFI +K+W T V + E SL+ L DY+DLY +HWP Sbjct: 67 YRREDLFIATKVWPTHFAYHDVLKSCEESLKKLGTDYVDLYQLHWPN------------- 113 Query: 499 DGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRIL 630 V +T A+E LV G +R +G+SNF+ K+++ + Sbjct: 114 ------PSVSIKETMSAMEKLVDEGRIRYIGISNFSVKEMKEAM 151 >UniRef50_Q4V008 Cluster: Oxidoreductase; n=4; Proteobacteria|Rep: Oxidoreductase - Xanthomonas campestris pv. campestris (strain 8004) Length = 267 Score = 89.8 bits (213), Expect = 2e-16 Identities = 56/150 (37%), Positives = 83/150 (55%) Frame = +1 Query: 154 IPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQEGVVKRED 333 +P G+GT++ K V +V++A+ +GYR I A +Y NE +VG+AI + V R+ Sbjct: 3 VPAFGLGTFRLKDQVVIDSVRNALALGYRAIDTAQIYDNEAQVGQAIA----DAGVPRDQ 58 Query: 334 LFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTDADGKIQ 513 LF+T+K+W D ++ +L+ SLR L DY+DL LIHWP P D Q Sbjct: 59 LFVTTKIWVDRFSRDTLQPSLQESLRKLGTDYVDLTLIHWPS---------PKD-----Q 104 Query: 514 FSDVDYVDTWKALEPLVCHGLVRSLGVSNF 603 +Y++ AL GL R++GVSNF Sbjct: 105 VPMREYLE---ALADAKAQGLTRAIGVSNF 131 >UniRef50_Q6WGK4 Cluster: Aldose reductase; n=1; Pristionchus pacificus|Rep: Aldose reductase - Pristionchus pacificus Length = 293 Score = 89.4 bits (212), Expect = 2e-16 Identities = 54/168 (32%), Positives = 89/168 (52%), Gaps = 1/168 (0%) Frame = +1 Query: 151 KIPVIGIGTWKSKPGEV-TQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQEGVVKR 327 ++P+IG+GT++ + V T + +A +GYR I A +Y NE +G + +++ +KR Sbjct: 15 RMPMIGVGTYQVQSQSVLTDTIDEAFRLGYRFIDTAQIYRNEAILGRILPDLLEKHSLKR 74 Query: 328 EDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTDADGK 507 ED+FITSK+ ++ SL +L Y+DL LIHWP + ++ Sbjct: 75 EDIFITSKVSPINQGKGKTSKSVLKSLTDLQTPYIDLVLIHWPGTSR-----LKSNHKDN 129 Query: 508 IQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKP 651 +F YV+ LE L+ G +RS+GVSN+ K L+ +L + P Sbjct: 130 AKFRAETYVE----LETLMDEGKIRSIGVSNYEIKHLETLLAECRILP 173 Score = 34.7 bits (76), Expect = 6.8 Identities = 12/32 (37%), Positives = 18/32 (56%) Frame = +2 Query: 659 NQVECHPYLNXKRLKQFCEDRDIMITXYSPXG 754 NQ ECHP+ L ++C+++ I YS G Sbjct: 176 NQCECHPHFRNSELAEYCKEKGIHFQAYSSLG 207 >UniRef50_Q4DJ59 Cluster: Aldo/keto reductase, putative; n=2; Trypanosoma|Rep: Aldo/keto reductase, putative - Trypanosoma cruzi Length = 322 Score = 89.4 bits (212), Expect = 2e-16 Identities = 58/176 (32%), Positives = 90/176 (51%), Gaps = 1/176 (0%) Frame = +1 Query: 118 SVPVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIK 297 ++P+ S G +IP +G+GT++ E AV A+ +G+R + A Y NE+ VG A Sbjct: 14 ALPLLESSGGMRIPHMGVGTYELYGDESRIAVLAALRLGFRLVDTAAGYHNEEHVGAA-- 71 Query: 298 TKIQEGVVKREDLFITSKLW-NTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKED 474 I+E V+RE+LF+ K+ +LV + S+R L I Y D LIHWP Sbjct: 72 --IEESGVQREELFVVVKIAPKAMASEELVEKGIRESVRKLRIAYADCVLIHWPGC---- 125 Query: 475 DAIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNAS 642 + P +A+G WK ++ L G++R LGVSNF + ++ NA+ Sbjct: 126 GGLKPEEAEGHRAARH----RCWKVMQALKKEGIIRHLGVSNFAPRHFPHLVGNAA 177 Score = 35.5 bits (78), Expect = 3.9 Identities = 14/32 (43%), Positives = 19/32 (59%) Frame = +2 Query: 653 VTNQVECHPYLNXKRLKQFCEDRDIMITXYSP 748 V NQ+E HP + FC +RDI++ YSP Sbjct: 192 VINQIELHPLCVQQEACDFCRERDIILQQYSP 223 >UniRef50_Q5V6N9 Cluster: Alcohol dehydrogenase; n=2; Halobacteriaceae|Rep: Alcohol dehydrogenase - Haloarcula marismortui (Halobacterium marismortui) Length = 667 Score = 89.4 bits (212), Expect = 2e-16 Identities = 55/185 (29%), Positives = 87/185 (47%), Gaps = 18/185 (9%) Frame = +1 Query: 151 KIPVIGIGTWKSKPG---EVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQEGVV 321 ++P IG G + + G + ++ A+D GYR + A +YGNE +G + G Sbjct: 377 RLPAIGFGCSRYRDGTYIDRADSIAAALDAGYRLLDSAELYGNEHRIGRILAAP---GAP 433 Query: 322 KREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAY------------ 465 R +FI K+W T HR + A SL L ID D Y +HWP+A Sbjct: 434 DRRRVFILGKVWRTNHRRKHMLTACRSSLDELGIDAFDCYALHWPEALAHRGSLTRLAEK 493 Query: 466 ---KEDDAIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDN 636 +++ FP + G I+ V W+ LE L G R+LG+ N + QL+ +++ Sbjct: 494 SVARQEALTFPKNDRGDIETDSVSLQRAWENLEALHERGWTRTLGLCNVSQTQLETVIET 553 Query: 637 ASVKP 651 +V+P Sbjct: 554 GTVRP 558 >UniRef50_A5ZYE6 Cluster: Putative uncharacterized protein; n=1; Ruminococcus obeum ATCC 29174|Rep: Putative uncharacterized protein - Ruminococcus obeum ATCC 29174 Length = 263 Score = 89.0 bits (211), Expect = 3e-16 Identities = 58/167 (34%), Positives = 87/167 (52%), Gaps = 1/167 (0%) Frame = +1 Query: 154 IPVIGIGTWKSKPG-EVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQEGVVKRE 330 +P++G+G +K+ E A+ A+ GYR + A Y NE+ VG I + V R+ Sbjct: 1 MPLLGLGLYKTTDAVEAEDAIAAAVQNGYRLLDTASAYKNEEFVG----CGIAKCGVPRK 56 Query: 331 DLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTDADGKI 510 DLFIT+K+WN R V GA + SL L +DY+DLYLIHWP G Sbjct: 57 DLFITTKIWNNAQRLGDVEGAFQRSLDRLGLDYIDLYLIHWP-------------VPG-- 101 Query: 511 QFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKP 651 +++TWK +E ++ G S+GVSNF + L+ + + + P Sbjct: 102 -----CFLNTWKDMEKILESGRALSIGVSNFEIRHLEELRRVSGIVP 143 Score = 37.9 bits (84), Expect = 0.73 Identities = 13/30 (43%), Positives = 19/30 (63%) Frame = +2 Query: 659 NQVECHPYLNXKRLKQFCEDRDIMITXYSP 748 NQ+ECHP K L ++C+ DI + Y+P Sbjct: 146 NQIECHPLCYPKELIEYCQANDIQVQAYAP 175 >UniRef50_Q03U37 Cluster: Aldo/keto reductase of diketogulonate reductase family; n=5; Lactobacillus|Rep: Aldo/keto reductase of diketogulonate reductase family - Lactobacillus brevis (strain ATCC 367 / JCM 1170) Length = 282 Score = 88.6 bits (210), Expect = 4e-16 Identities = 66/184 (35%), Positives = 93/184 (50%), Gaps = 4/184 (2%) Frame = +1 Query: 112 MTSVPVTT---LSNGAKIPVIGIGTWK-SKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKE 279 MT +T L++G ++PV+G GT+ + + A++ A D GYR A +Y NE Sbjct: 1 MTPTEITATRKLADGRQMPVMGFGTYLLNDQPTMNTAIQTAWDAGYRMFDTAMLYRNEDI 60 Query: 280 VGEAIKTKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQ 459 +G AI+ Q G+ RE LF+TSK+ D A+E SL+ L DYLDL LIHWP Sbjct: 61 LGPAIQ---QLGL-PREGLFLTSKVAEIVQGYDQTMKAVEGSLKRLQTDYLDLLLIHWP- 115 Query: 460 AYKEDDAIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNA 639 +E + DTW+ALE L G V+S+GVSN+ L+ + A Sbjct: 116 -VRE------------------HFFDTWRALEQLKADGQVKSIGVSNYTIAHLELLATKA 156 Query: 640 SVKP 651 P Sbjct: 157 KEMP 160 Score = 38.7 bits (86), Expect = 0.42 Identities = 16/34 (47%), Positives = 22/34 (64%) Frame = +2 Query: 653 VTNQVECHPYLNXKRLKQFCEDRDIMITXYSPXG 754 V NQVE HPYLN + L + ++ DI+ +SP G Sbjct: 161 VVNQVEYHPYLNQQALADYDQEHDIVTEAWSPLG 194 >UniRef50_A7BES9 Cluster: Putative uncharacterized protein; n=1; Actinomyces odontolyticus ATCC 17982|Rep: Putative uncharacterized protein - Actinomyces odontolyticus ATCC 17982 Length = 282 Score = 88.6 bits (210), Expect = 4e-16 Identities = 71/241 (29%), Positives = 111/241 (46%) Frame = +1 Query: 133 TLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQE 312 TL+NG IP +G+GT+ +P + AV A+D Y I A VY NE+ VG ++ + Sbjct: 5 TLNNGITIPQVGLGTYLLEPDDAQSAVTYALDNDYTLIDTANVYVNERAVGRGMRASSK- 63 Query: 313 GVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPT 492 R+++F+ +KLW +F A+E +L L DY+DL ++H P Sbjct: 64 ---ARDEIFLETKLWPSFFER---ASAVEETLERLGTDYIDLMILHQPAG---------- 107 Query: 493 DADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPGH*PGRM 672 D V ++ LE G +R++G+SNF+ Q QRILD V P Sbjct: 108 -----------DTVAGYRILEKAHKEGKIRAIGLSNFDVAQTQRILDECEVVPTINQVEC 156 Query: 673 PSVFKPXAIEAVLRRP*YYDNGVLPRWGXPDRPWAKPGDPHLMEDPKLKEIADRLGKXAA 852 F ++A+L+ N L W P G+ +M +P ++ +A+ K A Sbjct: 157 HPYFPQTELKALLKD----HNITLQAW----YPLGGRGNDSIMSEPIVQGLAEEHSKSPA 208 Query: 853 Q 855 Q Sbjct: 209 Q 209 >UniRef50_A3VRL4 Cluster: Putative uncharacterized protein; n=1; Parvularcula bermudensis HTCC2503|Rep: Putative uncharacterized protein - Parvularcula bermudensis HTCC2503 Length = 278 Score = 88.2 bits (209), Expect = 5e-16 Identities = 41/101 (40%), Positives = 64/101 (63%) Frame = +1 Query: 154 IPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQEGVVKRED 333 IP +G GTW+ + + + + AI+ GYRHI A +Y NEK+VGE IK + + R++ Sbjct: 11 IPRLGFGTWQLEGEDARTSTRTAIETGYRHIDGAAIYKNEKKVGEGIK----DSGIPRDE 66 Query: 334 LFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWP 456 LF+T+K+WN + A++ SL L +DY++L L+HWP Sbjct: 67 LFVTTKIWNEDIQKGRHSEAVDESLDRLGLDYVNLILLHWP 107 >UniRef50_Q5KD52 Cluster: Oxidoreductase, putative; n=1; Filobasidiella neoformans|Rep: Oxidoreductase, putative - Cryptococcus neoformans (Filobasidiella neoformans) Length = 321 Score = 88.2 bits (209), Expect = 5e-16 Identities = 66/177 (37%), Positives = 92/177 (51%), Gaps = 4/177 (2%) Frame = +1 Query: 133 TLSNGAKIPVIGIGTWKSKPGEVTQ-AVKDAIDIGYRHIXCA---FVYGNEKEVGEAIKT 300 TL++G +IP I GTWK P EVT V AID+G+ HI A VY NE+EVG+AIK Sbjct: 7 TLNDGHRIPAIAFGTWKI-PKEVTPFQVGQAIDVGFDHIDTAQGRIVYHNEEEVGQAIK- 64 Query: 301 KIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDA 480 E + R L++T+K W+ R ++ SL L ++YLDLYLIH PQ K D Sbjct: 65 ---ESGLSRNQLWVTTK-WSGIDGKG-ARQSIGESLEKLGLEYLDLYLIHSPQVTKGDIK 119 Query: 481 IFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKP 651 + + + + K + S +FN +QLQ +L +A+VKP Sbjct: 120 GAWKELETLQKEGKTKSIGVSKQVYYQTIFFASLSDVWDSFNKEQLQELLAHATVKP 176 >UniRef50_UPI00005A2CCB Cluster: PREDICTED: similar to Aldose reductase (AR) (Aldehyde reductase); n=1; Canis lupus familiaris|Rep: PREDICTED: similar to Aldose reductase (AR) (Aldehyde reductase) - Canis familiaris Length = 182 Score = 87.4 bits (207), Expect = 9e-16 Identities = 39/78 (50%), Positives = 55/78 (70%) Frame = +1 Query: 136 LSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQEG 315 L NG K+P++G+ TWKS P +VT+AVK +D+GY HI C N++EVG A++ K++ Sbjct: 25 LGNGIKVPIMGLATWKSPPSKVTEAVKVVMDLGYCHIDCTHKLQNKREVGLAVQEKLKGQ 84 Query: 316 VVKREDLFITSKLWNTFH 369 VKREDL I S+L +T H Sbjct: 85 GVKREDLSILSELQHTHH 102 >UniRef50_P15339 Cluster: 2,5-diketo-D-gluconic acid reductase B; n=6; Actinomycetales|Rep: 2,5-diketo-D-gluconic acid reductase B - Corynebacterium sp. (strain SHS752001) Length = 277 Score = 87.0 bits (206), Expect = 1e-15 Identities = 58/180 (32%), Positives = 88/180 (48%) Frame = +1 Query: 112 MTSVPVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEA 291 M ++P +L++G G+GT+ + E A+ AID GYR + A Y NE EVG A Sbjct: 1 MPNIPTISLNDGRPFAEPGLGTYNLRGDEGVAAMVAAIDSGYRLLDTAVNYENESEVGRA 60 Query: 292 IKTKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKE 471 ++ V R++L + SK+ H ++ SL L +D +DL LIHW Sbjct: 61 VRA----SSVDRDELIVASKIPGRQHGRAEAVDSIRGSLDRLGLDVIDLQLIHW------ 110 Query: 472 DDAIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKP 651 P + G+ ++DTW+ + GLVRS+GVSNF L+ ++D V P Sbjct: 111 -----PNPSVGR-------WLDTWRGMIDAREAGLVRSIGVSNFTEPMLKTLIDETGVTP 158 >UniRef50_Q6U5V3 Cluster: Putative uncharacterized protein; n=1; Klebsiella pneumoniae|Rep: Putative uncharacterized protein - Klebsiella pneumoniae Length = 279 Score = 86.6 bits (205), Expect = 2e-15 Identities = 56/172 (32%), Positives = 84/172 (48%) Frame = +1 Query: 136 LSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQEG 315 L++G +P G G W +V ++ A+ G+RH A Y NE VG A++ Sbjct: 8 LNDGYYMPRPGCGLWLIDNRDVDSLIRQALKAGFRHFDTAQAYFNEDGVGRALRYT---- 63 Query: 316 VVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTD 495 V RE LFITSK+ + +L L ++YL+L+LIHWP K Sbjct: 64 EVPREQLFITSKIRGRDMGYARTLVSFNETLERLGVEYLELFLIHWPIPAKN-------- 115 Query: 496 ADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKP 651 YV+TW+A L GL+RS+GVSNF + ++R++++ V P Sbjct: 116 ----------LYVETWEASIELEASGLIRSIGVSNFTCQHIERLIEDTGVVP 157 >UniRef50_A2RMU6 Cluster: Oxidoreductase, aldo/keto reductase family; n=3; Lactococcus lactis|Rep: Oxidoreductase, aldo/keto reductase family - Lactococcus lactis subsp. cremoris (strain MG1363) Length = 281 Score = 86.6 bits (205), Expect = 2e-15 Identities = 76/243 (31%), Positives = 116/243 (47%), Gaps = 3/243 (1%) Frame = +1 Query: 136 LSNGAKIPVIGIGTWKSKPGEVTQ-AVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQE 312 L++G IP G+G ++ GE T+ AVK+A+ +GYRHI A Y NE+ VG AI + Sbjct: 7 LNDGNIIPQFGLGVYQIPEGEATENAVKEALRLGYRHIDTAHAYQNERSVGRAIHS---S 63 Query: 313 GVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPT 492 G+ E ++ITSKLW + + D A+E L LN+ +DL L+H Sbjct: 64 GIPISE-IWITSKLWPSDY--DDASQAIERMLELLNLKQIDLLLLHQQVG---------- 110 Query: 493 DADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPGH*PGRM 672 +Y W ALE V G V+S+G+SNF+ ++L + + A +K P + Sbjct: 111 -----------NYRKAWIALENAVKSGKVKSIGISNFDGERLVDLFNFADIK----PSAL 155 Query: 673 PSVFKPXAIEAVLRRP*YYDNGVLPRWGXPDRPW--AKPGDPHLMEDPKLKEIADRLGKX 846 P + L+ L +G W GD L+++ +LK+IA + K Sbjct: 156 QVETHPYHQQKELQE-------FLKPYGTKIESWYPLGHGDQRLLDESRLKKIAQKYNKT 208 Query: 847 AAQ 855 AQ Sbjct: 209 VAQ 211 >UniRef50_A0L1A2 Cluster: Aldo/keto reductase; n=8; Gammaproteobacteria|Rep: Aldo/keto reductase - Shewanella sp. (strain ANA-3) Length = 280 Score = 86.6 bits (205), Expect = 2e-15 Identities = 65/176 (36%), Positives = 90/176 (51%), Gaps = 3/176 (1%) Frame = +1 Query: 112 MTSVPVTTLSNGAKI---PVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEV 282 MT TT SN A + P++G GT++ K AV A++ G RHI A +YGNE+ V Sbjct: 1 MTQTNATT-SNQAPLTAMPMLGTGTFRLKDNAAFDAVLMALEEGSRHIDTAQIYGNEQAV 59 Query: 283 GEAIKTKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQA 462 G+AI T + RE+LFIT+K+W + ++ SL L YLDL LIHWP Sbjct: 60 GDAINTS----GIPREELFITTKVWTENLTKERFETSVIDSLTALQTKYLDLLLIHWPLN 115 Query: 463 YKEDDAIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRIL 630 E S V+Y+ KA+ + GL R +GVSNF + QL + + Sbjct: 116 SDEP--------------SMVEYLSELKAV---LDKGLTRRIGVSNFTNAQLAQAI 154 Score = 40.7 bits (91), Expect = 0.10 Identities = 14/31 (45%), Positives = 21/31 (67%) Frame = +2 Query: 656 TNQVECHPYLNXKRLKQFCEDRDIMITXYSP 748 TNQVE HPYL +++ FC ++++T Y P Sbjct: 164 TNQVEVHPYLINRKVTDFCRQHNVLVTGYMP 194 >UniRef50_Q4WUF7 Cluster: Aldo-keto reductase, putative; n=3; Pezizomycotina|Rep: Aldo-keto reductase, putative - Aspergillus fumigatus (Sartorya fumigata) Length = 283 Score = 86.6 bits (205), Expect = 2e-15 Identities = 58/175 (33%), Positives = 91/175 (52%), Gaps = 2/175 (1%) Frame = +1 Query: 139 SNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQEGV 318 ++ KIP +G G ++S G+ Q+ A++ GYRHI A YGNEKEVGEA++ + Sbjct: 15 NSDVKIPRLGFGVYRSPTGQCVQSSLRALEAGYRHIDTAQFYGNEKEVGEALR----KCG 70 Query: 319 VKREDLFITSKLWNTFHRPDLVRGALEVSLRNL--NIDYLDLYLIHWPQAYKEDDAIFPT 492 + R D+F+T+K+ + P+ L S+ + Y+DL+LIH + Sbjct: 71 IPRSDVFVTTKILSPAGSPEATYQKLLESVEKIGGRDGYVDLFLIH-------------S 117 Query: 493 DADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPGH 657 + G ++ W+ALE L+ G RS+GVSNF K ++ + A V P H Sbjct: 118 SSSGSAGRKEL-----WQALERLLEEGKTRSIGVSNFGVKHIEEMKAYAKVWPPH 167 >UniRef50_Q11DV1 Cluster: Aldo/keto reductase; n=10; Alphaproteobacteria|Rep: Aldo/keto reductase - Mesorhizobium sp. (strain BNC1) Length = 274 Score = 85.0 bits (201), Expect = 5e-15 Identities = 38/109 (34%), Positives = 63/109 (57%) Frame = +1 Query: 130 TTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQ 309 T ++GA IP +G G ++ EV + + A++ G+RH A +Y NE +G A+ + Sbjct: 3 TVTAHGATIPALGFGVFRMSDAEVERIIPAALEAGFRHFDTAQIYQNEAALGRAL----E 58 Query: 310 EGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWP 456 +REDLF+T+K+W + D +++ SL L +D +DL L+HWP Sbjct: 59 RAGARREDLFLTTKVWVDNYSADKFAASVDESLEKLKVDQVDLLLLHWP 107 Score = 35.5 bits (78), Expect = 3.9 Identities = 19/47 (40%), Positives = 23/47 (48%), Gaps = 2/47 (4%) Frame = +2 Query: 653 VTNQVECHPYLNXKRLKQFCEDRDIMITXY--SPXGXLPTDPGLSLV 787 VTNQVE HPYL L D + +T Y G +P DP L + Sbjct: 154 VTNQVELHPYLPQHSLVAAARDSAVAVTAYYGMADGAVPKDPVLQQI 200 >UniRef50_O14088 Cluster: Xylose and arabinose reductase; n=1; Schizosaccharomyces pombe|Rep: Xylose and arabinose reductase - Schizosaccharomyces pombe (Fission yeast) Length = 275 Score = 85.0 bits (201), Expect = 5e-15 Identities = 54/167 (32%), Positives = 84/167 (50%) Frame = +1 Query: 136 LSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQEG 315 L+NG K P G++ + +V A+ GYRHI A +Y NE + G AI ++E Sbjct: 8 LNNGLKCPQFAYGSYMVNRTKCFDSVYAALQCGYRHIDSAQMYHNEADCGRAILKFMEET 67 Query: 316 VVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTD 495 KRED++ TSKL N +++ S++ + Y+DL+L+H P Sbjct: 68 GTKREDIWFTSKL-NDLSGYKSTLSSIDASVKACGLGYIDLFLLHSPYG----------- 115 Query: 496 ADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDN 636 D +++WKALE V G +R++GVSNF +Q +LD+ Sbjct: 116 ----------DRIESWKALEKGVEEGKLRAIGVSNFGPHHIQELLDS 152 Score = 34.3 bits (75), Expect = 9.0 Identities = 10/30 (33%), Positives = 20/30 (66%) Frame = +2 Query: 659 NQVECHPYLNXKRLKQFCEDRDIMITXYSP 748 NQ+E HP+ + +++ +CE + I + Y+P Sbjct: 161 NQIELHPFCSQQKVVDYCESKGIQLAAYAP 190 >UniRef50_A7D6Q0 Cluster: Aldo/keto reductase; n=1; Halorubrum lacusprofundi ATCC 49239|Rep: Aldo/keto reductase - Halorubrum lacusprofundi ATCC 49239 Length = 309 Score = 85.0 bits (201), Expect = 5e-15 Identities = 57/168 (33%), Positives = 87/168 (51%), Gaps = 1/168 (0%) Frame = +1 Query: 118 SVPVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIK 297 ++P TL +G +P +G+GT+ ++ +V+ A+ GY HI A Y NE+ +GE + Sbjct: 33 TIPTQTLPSGDTLPALGLGTYALDDDQIADSVRAALSSGYTHIDTAEGYHNEEAIGEVL- 91 Query: 298 TKIQEGVVKREDLFITSK-LWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKED 474 R+D+F+TSK L L++ + E SL L DYLDLYLIHWP Sbjct: 92 -----AEYDRDDVFLTSKVLAKNLGYESLIQ-SCEASLERLETDYLDLYLIHWPN----- 140 Query: 475 DAIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQL 618 P + ++ +A+ L GLVR++GVSNF++ QL Sbjct: 141 ----PA----------ISLRESLQAMAELHDRGLVRNVGVSNFSAYQL 174 >UniRef50_P91021 Cluster: Putative uncharacterized protein; n=1; Caenorhabditis elegans|Rep: Putative uncharacterized protein - Caenorhabditis elegans Length = 134 Score = 84.6 bits (200), Expect = 6e-15 Identities = 44/84 (52%), Positives = 54/84 (64%) Frame = +1 Query: 133 TLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQE 312 TLSN +P +G+GTW+S +V AVK A+ GY I A Y NE+ +G AIK I E Sbjct: 49 TLSNAHSMPAVGLGTWQSNAEDVISAVKAAVKNGYSLIDTASGYNNEEFIGTAIKEVIAE 108 Query: 313 GVVKREDLFITSKLWNTFHRPDLV 384 GVVKREDLFIT+K+ N F LV Sbjct: 109 GVVKREDLFITTKVPNLFSSLRLV 132 >UniRef50_Q4P1G1 Cluster: Putative uncharacterized protein; n=1; Ustilago maydis|Rep: Putative uncharacterized protein - Ustilago maydis (Smut fungus) Length = 320 Score = 84.6 bits (200), Expect = 6e-15 Identities = 55/172 (31%), Positives = 91/172 (52%), Gaps = 1/172 (0%) Frame = +1 Query: 121 VPVTTLSNGAKIPVIGIGTWKSK-PGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIK 297 +P L++G ++P + GT + + + V A+D G+R I A VY NE +G I+ Sbjct: 3 IPTVRLASGLELPRLAFGTGTALYNSDAAKQVTMALDSGFRFIDGAEVYANEASMGAGIE 62 Query: 298 TKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDD 477 + + +KR D+++ +K+ + DL + A++V L+ L +D LD YL+H P Sbjct: 63 SFLASSGLKRNDIYVLTKVGKEGMK-DL-QSAIKVELQKLKVDQLDSYLLHLP------- 113 Query: 478 AIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILD 633 P DG VD WK LE + GL +S+GVSN+ + +Q++LD Sbjct: 114 ---PRGQDGL-----PSNVDAWKELEKIKQAGLTKSIGVSNWLASDIQQLLD 157 >UniRef50_Q8ZH36 Cluster: 2,5-diketo-D-gluconic acid reductase B; n=91; Proteobacteria|Rep: 2,5-diketo-D-gluconic acid reductase B - Yersinia pestis Length = 267 Score = 84.6 bits (200), Expect = 6e-15 Identities = 44/106 (41%), Positives = 63/106 (59%) Frame = +1 Query: 154 IPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQEGVVKRED 333 IPV G+GT++ + V +V A+ +GYR I A +Y NE VG+AI QE + R++ Sbjct: 3 IPVFGLGTFRLQDQIVIDSVSQALTLGYRAIDTAQIYENEAPVGQAI----QESGINRDE 58 Query: 334 LFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKE 471 LFIT+K+W D + +L S++ L DY+DL LIHWP E Sbjct: 59 LFITTKIWIANLSKDKLIPSLRESIQKLKTDYVDLTLIHWPSPNDE 104 >UniRef50_UPI000155CAC7 Cluster: PREDICTED: hypothetical protein; n=1; Ornithorhynchus anatinus|Rep: PREDICTED: hypothetical protein - Ornithorhynchus anatinus Length = 419 Score = 84.2 bits (199), Expect = 9e-15 Identities = 61/159 (38%), Positives = 85/159 (53%), Gaps = 3/159 (1%) Frame = +1 Query: 121 VPVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAI-DIGYRHIXCAFVYGNEKEVGEAIK 297 VP L+NG IP++G+GT G AV A+ + G RHI A YG E +G+AI Sbjct: 12 VPTVPLANGLNIPILGLGT-SHVGGYSHDAVIYALKECGIRHIDTAKRYGCELLLGKAI- 69 Query: 298 TKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDD 477 QE VKRE+L+IT+KLW T + + + + S L ++YLDL+LIHWP D Sbjct: 70 ---QESGVKREELWITTKLWLTDYGYESAKQSCLESCNRLGVEYLDLFLIHWP------D 120 Query: 478 AIFPTDADGKIQFSDVDYVDTWKALEPLV--CHGLVRSL 588 A P + + + +TW+A+E L H L SL Sbjct: 121 AQLPGKSSREAR------AETWRAMEELYDQVHNLQSSL 153 >UniRef50_Q7M4N1 Cluster: Dihydrodiol dehydrogenase DD2; n=2; Homo sapiens|Rep: Dihydrodiol dehydrogenase DD2 - Homo sapiens (Human) Length = 188 Score = 69.7 bits (163), Expect(2) = 1e-14 Identities = 34/61 (55%), Positives = 43/61 (70%) Frame = +1 Query: 220 AIDIGYRHIXCAFVYGNEKEVGEAIKTKIQEGVVKREDLFITSKLWNTFHRPDLVRGALE 399 AI+ G+ HI A VY NE++VG I +G VKRED+F TSKLW+ HRP+LVR ALE Sbjct: 2 AIEAGFHHIDSAHVYNNEEQVG------IADGSVKREDIFYTSKLWSNSHRPELVRPALE 55 Query: 400 V 402 + Sbjct: 56 I 56 Score = 43.6 bits (98), Expect = 0.015 Identities = 19/40 (47%), Positives = 25/40 (62%) Frame = +2 Query: 653 VTNQVECHPYLNXKRLKQFCEDRDIMITXYSPXGXLPTDP 772 V NQVECHPY N ++L FC +DI++ YS G +P Sbjct: 98 VCNQVECHPYFNQRKLLDFC--KDIVLVAYSALGSHREEP 135 Score = 34.3 bits (75), Expect(2) = 1e-14 Identities = 19/48 (39%), Positives = 28/48 (58%) Frame = +1 Query: 505 KIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVK 648 +I F VD TW+A+E +S+GVSNFN + L+ IL+ +K Sbjct: 55 EILFDTVDLCATWEAME--------KSIGVSNFNHRLLEMILNKPGLK 94 >UniRef50_Q8EVS8 Cluster: Oxidoreductase; n=1; Mycoplasma penetrans|Rep: Oxidoreductase - Mycoplasma penetrans Length = 289 Score = 83.4 bits (197), Expect = 1e-14 Identities = 50/115 (43%), Positives = 67/115 (58%), Gaps = 1/115 (0%) Frame = +1 Query: 115 TSVPVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAI 294 ++V + TL+NG KIP IG G ++ E VK AI IGYR I A Y NEKE G I Sbjct: 4 SNVKLITLNNGNKIPSIGFGVFQIPKEETADCVKKAISIGYRLIDTAQAYHNEKETGLGI 63 Query: 295 KTKIQEGVVKREDLFITSKLW-NTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWP 456 K VKRE++F+T+K+W + + R +E SL+ L+ YLDL L+H P Sbjct: 64 KL----SGVKREEIFLTTKVWVSNYER--CYESVIE-SLKRLDTSYLDLILLHQP 111 Database: uniref50 Posted date: Oct 5, 2007 11:19 AM Number of letters in database: 575,637,011 Number of sequences in database: 1,657,284 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.279 0.0580 0.190 Matrix: BLOSUM62 Gap Penalties: Existence: 9, Extension: 2 Number of Hits to DB: 1,023,252,796 Number of Sequences: 1657284 Number of extensions: 18490190 Number of successful extensions: 52015 Number of sequences better than 10.0: 500 Number of HSP's better than 10.0 without gapping: 48502 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 51438 length of database: 575,637,011 effective HSP length: 104 effective length of database: 403,279,475 effective search space used: 171393776875 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 37 (14.9 bits) X3: 62 (25.0 bits) S1: 41 (21.7 bits)
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