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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= 030731E7_G07_e631_13.seq
         (1589 letters)

Database: uniref50 
           1,657,284 sequences; 575,637,011 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

UniRef50_Q7PCV3 Cluster: ENSANGP00000031808; n=9; Endopterygota|...   276   1e-72
UniRef50_Q2LZ66 Cluster: GA19341-PA; n=2; Endopterygota|Rep: GA1...   259   1e-67
UniRef50_P45376 Cluster: Aldose reductase; n=21; Bilateria|Rep: ...   257   5e-67
UniRef50_P15121 Cluster: Aldose reductase; n=72; Eumetazoa|Rep: ...   249   2e-64
UniRef50_Q8CI22 Cluster: 2310005E10Rik protein; n=30; Tetrapoda|...   243   9e-63
UniRef50_Q9VTL0 Cluster: CG6083-PA; n=4; Diptera|Rep: CG6083-PA ...   241   5e-62
UniRef50_UPI00015B56A2 Cluster: PREDICTED: similar to GA10458-PA...   227   5e-58
UniRef50_P14550 Cluster: Alcohol dehydrogenase [NADP+]; n=44; Bi...   226   1e-57
UniRef50_Q9NAI5 Cluster: Putative uncharacterized protein; n=3; ...   218   3e-55
UniRef50_UPI0000588153 Cluster: PREDICTED: hypothetical protein;...   204   7e-51
UniRef50_Q7QK25 Cluster: ENSANGP00000019775; n=2; Anopheles gamb...   204   7e-51
UniRef50_Q0VGY1 Cluster: 3-alpha-hydroxysteroid dehydrogenase; n...   202   3e-50
UniRef50_Q17DN0 Cluster: Aldo-keto reductase; n=5; Culicidae|Rep...   195   3e-48
UniRef50_UPI00015B56A3 Cluster: PREDICTED: similar to aldo-keto ...   192   2e-47
UniRef50_Q2S340 Cluster: Aldehyde reductase; n=10; Bacteria|Rep:...   190   9e-47
UniRef50_A5KSS3 Cluster: Aldehyde reductase; n=1; candidate divi...   190   1e-46
UniRef50_Q8K023 Cluster: Aldo-keto reductase family 1 member C18...   185   2e-45
UniRef50_A2QBD7 Cluster: Catalytic activity: an alcohol + NADP(+...   184   8e-45
UniRef50_UPI000065D0BD Cluster: Homolog of Homo sapiens "AKR1B1 ...   183   1e-44
UniRef50_A7SIT3 Cluster: Predicted protein; n=1; Nematostella ve...   183   1e-44
UniRef50_Q10494 Cluster: Probable oxidoreductase C26F1.07; n=2; ...   182   2e-44
UniRef50_P51857 Cluster: 3-oxo-5-beta-steroid 4-dehydrogenase (E...   182   3e-44
UniRef50_Q7JVH6 Cluster: LD24696p; n=2; Sophophora|Rep: LD24696p...   181   4e-44
UniRef50_UPI0000E4A7CE Cluster: PREDICTED: similar to LOC553452 ...   180   1e-43
UniRef50_Q96JD6-2 Cluster: Isoform 2 of Q96JD6 ; n=4; Catarrhini...   180   1e-43
UniRef50_Q96JD6 Cluster: Aldo-keto reductase family 1 member C-l...   180   1e-43
UniRef50_Q0PGJ6 Cluster: Aldo-keto reductase; n=32; Magnoliophyt...   179   2e-43
UniRef50_P27800 Cluster: Aldehyde reductase 1; n=18; root|Rep: A...   179   2e-43
UniRef50_Q8VC28 Cluster: Aldo-keto reductase family 1 member C13...   179   2e-43
UniRef50_Q54B70 Cluster: Aldehyde reductase; n=2; Dictyostelium ...   178   4e-43
UniRef50_UPI0000E45E29 Cluster: PREDICTED: similar to aldose red...   177   9e-43
UniRef50_Q5BKE9 Cluster: LOC594893 protein; n=5; Xenopus tropica...   175   4e-42
UniRef50_Q96UH3 Cluster: Aldehyde reductase; n=13; Pezizomycotin...   174   5e-42
UniRef50_A4RQH8 Cluster: Predicted protein; n=2; Ostreococcus|Re...   172   2e-41
UniRef50_Q2V420 Cluster: Uncharacterized protein At2g37770.1; n=...   171   6e-41
UniRef50_UPI0000498F1F Cluster: oxidoreductase, aldo/keto reduct...   168   3e-40
UniRef50_Q0IBY6 Cluster: Alcohol dehydrogenase; n=2; Chroococcal...   167   7e-40
UniRef50_UPI0000D9A956 Cluster: PREDICTED: similar to aldo-keto ...   167   9e-40
UniRef50_Q7QVQ9 Cluster: GLP_302_44328_45269; n=1; Giardia lambl...   166   2e-39
UniRef50_A3U9Y0 Cluster: Aldehyde reductase; n=5; Bacteroidetes|...   165   4e-39
UniRef50_A2R6Z3 Cluster: Catalytic activity: an alcohol + NADP(+...   164   5e-39
UniRef50_Q22352 Cluster: Putative uncharacterized protein T08H10...   162   3e-38
UniRef50_Q2UGR1 Cluster: Aldo/keto reductase family proteins; n=...   160   8e-38
UniRef50_A2EYY6 Cluster: Oxidoreductase, aldo/keto reductase fam...   159   2e-37
UniRef50_P38715 Cluster: NADPH-dependent aldose reductase GRE3; ...   159   2e-37
UniRef50_Q1IN88 Cluster: Aldehyde reductase; n=5; Bacteria|Rep: ...   159   2e-37
UniRef50_Q9U2J5 Cluster: Putative uncharacterized protein; n=2; ...   158   4e-37
UniRef50_A2FPE2 Cluster: Oxidoreductase, aldo/keto reductase fam...   158   4e-37
UniRef50_Q4PAT5 Cluster: Putative uncharacterized protein; n=1; ...   157   6e-37
UniRef50_Q8SSK6 Cluster: ALDOSE REDUCTASE; n=1; Encephalitozoon ...   157   1e-36
UniRef50_Q55FL3 Cluster: Aldo-keto reductase; n=2; Dictyostelium...   156   1e-36
UniRef50_Q7ZA52 Cluster: Aldose reductase; n=6; Pezizomycotina|R...   156   2e-36
UniRef50_A2QVE5 Cluster: Similarity: shows similarity to several...   156   2e-36
UniRef50_Q7PLK6 Cluster: CG40064-PA; n=1; Drosophila melanogaste...   155   2e-36
UniRef50_Q7ZWA4 Cluster: Zgc:56622; n=6; cellular organisms|Rep:...   154   5e-36
UniRef50_Q9VHX4 Cluster: CG2767-PA; n=4; Endopterygota|Rep: CG27...   154   5e-36
UniRef50_Q9Y020 Cluster: 3-dehydroecdysone 3beta-reductase precu...   153   1e-35
UniRef50_Q16K66 Cluster: Aldo-keto reductase; n=2; Aedes aegypti...   152   2e-35
UniRef50_A7CWF9 Cluster: Aldehyde reductase; n=2; Bacteria|Rep: ...   151   4e-35
UniRef50_P26690 Cluster: NAD(P)H-dependent 6'-deoxychalcone synt...   151   4e-35
UniRef50_UPI00015B4B22 Cluster: PREDICTED: similar to GA15457-PA...   151   7e-35
UniRef50_A2EHN6 Cluster: Oxidoreductase, aldo/keto reductase fam...   150   1e-34
UniRef50_A7PNI3 Cluster: Chromosome chr1 scaffold_22, whole geno...   149   2e-34
UniRef50_Q17G72 Cluster: Aldo-keto reductase; n=9; Endopterygota...   149   2e-34
UniRef50_Q6RZX1 Cluster: Gld1; n=22; Pezizomycotina|Rep: Gld1 - ...   149   3e-34
UniRef50_UPI000023D0F1 Cluster: hypothetical protein FG03517.1; ...   148   3e-34
UniRef50_Q0CLQ2 Cluster: Putative uncharacterized protein; n=1; ...   146   1e-33
UniRef50_Q1YPE5 Cluster: Aldehyde reductase; n=7; Bacteria|Rep: ...   146   2e-33
UniRef50_Q6CFG7 Cluster: Yarrowia lipolytica chromosome B of str...   146   2e-33
UniRef50_UPI00015B40FA Cluster: PREDICTED: similar to CG2767-PA;...   145   2e-33
UniRef50_Q6C2L0 Cluster: Yarrowia lipolytica chromosome F of str...   145   3e-33
UniRef50_Q03PG5 Cluster: Aldo/keto reductase of diketogulonate r...   144   4e-33
UniRef50_Q1U9L6 Cluster: 2,5-didehydrogluconate reductase; n=3; ...   144   6e-33
UniRef50_A1D4E3 Cluster: D-xylose reductase (Xyl1), putative; n=...   144   6e-33
UniRef50_P28475 Cluster: NADP-dependent D-sorbitol-6-phosphate d...   142   2e-32
UniRef50_Q6TY50 Cluster: Reductase 2; n=10; Magnoliophyta|Rep: R...   142   2e-32
UniRef50_Q5FK98 Cluster: Oxidoreductase; n=8; Lactobacillales|Re...   141   4e-32
UniRef50_Q5KI95 Cluster: Aldo-keto reductase, putative; n=14; Di...   141   4e-32
UniRef50_P23901 Cluster: Aldose reductase; n=9; Poaceae|Rep: Ald...   141   5e-32
UniRef50_Q23320 Cluster: Putative uncharacterized protein; n=4; ...   140   9e-32
UniRef50_UPI0000499B0E Cluster: oxidoreductase, aldo/keto reduct...   140   1e-31
UniRef50_A6W8E7 Cluster: 2,5-didehydrogluconate reductase; n=3; ...   140   1e-31
UniRef50_Q9FJK0 Cluster: Aldose reductase-like protein; n=3; cor...   140   1e-31
UniRef50_Q01J82 Cluster: OSIGBa0152K17.5 protein; n=28; Magnolio...   139   2e-31
UniRef50_Q41399 Cluster: Chalcone reductase; n=4; eudicotyledons...   138   3e-31
UniRef50_Q88SL1 Cluster: Oxidoreductase; n=51; Lactobacillales|R...   138   4e-31
UniRef50_A6WDZ5 Cluster: Aldo/keto reductase; n=5; Bacteria|Rep:...   138   5e-31
UniRef50_Q4FY75 Cluster: Aldo-keto reductase-like protein; n=5; ...   138   5e-31
UniRef50_A2QL02 Cluster: Putative frameshift; n=1; Aspergillus n...   136   2e-30
UniRef50_P14065 Cluster: Protein GCY; n=13; Saccharomycetales|Re...   136   2e-30
UniRef50_UPI0000519CC2 Cluster: PREDICTED: similar to CG2767-PA;...   136   2e-30
UniRef50_A5E082 Cluster: GCY protein; n=4; Saccharomycetales|Rep...   134   5e-30
UniRef50_A3LTU8 Cluster: D-arabinose dehydrogenase; n=5; Sacchar...   134   8e-30
UniRef50_Q8WRT0 Cluster: 3-dehydrecdysone 3b-reductase; n=1; Tri...   132   2e-29
UniRef50_P38115 Cluster: D-arabinose dehydrogenase [NAD(P)+] hea...   132   2e-29
UniRef50_Q5T2L2 Cluster: Aldo-keto reductase family 1 member C-l...   132   2e-29
UniRef50_Q968S3 Cluster: Aldoketoreductase-like protein; n=1; Or...   132   3e-29
UniRef50_P22045 Cluster: Probable reductase; n=101; cellular org...   132   3e-29
UniRef50_Q7N0E4 Cluster: 2,5-diketo-D-gluconic acid reductase A;...   130   8e-29
UniRef50_Q41E86 Cluster: 2,5-didehydrogluconate reductase; n=2; ...   130   8e-29
UniRef50_Q8J0K1 Cluster: 4-dihydromethyltrisporate dehydrogenase...   130   8e-29
UniRef50_Q4Q5N9 Cluster: Prostaglandin f synthase, putative; n=7...   130   1e-28
UniRef50_A6ESC0 Cluster: ARA1; n=1; unidentified eubacterium SCB...   128   5e-28
UniRef50_UPI00015B4912 Cluster: PREDICTED: similar to aldo-keto ...   127   7e-28
UniRef50_Q7PM68 Cluster: ENSANGP00000014386; n=1; Anopheles gamb...   127   7e-28
UniRef50_UPI0000D56CE5 Cluster: PREDICTED: similar to CG6084-PA,...   126   1e-27
UniRef50_Q01HB5 Cluster: OSIGBa0136O08-OSIGBa0153H12.9 protein; ...   126   1e-27
UniRef50_Q7G764 Cluster: Probable NAD(P)H-dependent oxidoreducta...   126   1e-27
UniRef50_Q03TW0 Cluster: Aldo/keto reductase of diketogulonate r...   126   2e-27
UniRef50_Q8ZI40 Cluster: 2,5-diketo-D-gluconic acid reductase A;...   126   2e-27
UniRef50_Q9ZBW7 Cluster: Putative oxidoreductase; n=2; Actinomyc...   125   4e-27
UniRef50_Q7G765 Cluster: Probable NAD(P)H-dependent oxidoreducta...   124   5e-27
UniRef50_P70883 Cluster: AkrI; n=1; Butyrivibrio fibrisolvens|Re...   124   9e-27
UniRef50_Q9HGY0 Cluster: Glycerol dehydrogenase; n=8; Saccharomy...   124   9e-27
UniRef50_Q9X0A2 Cluster: Oxidoreductase, aldo/keto reductase fam...   123   1e-26
UniRef50_Q7VG53 Cluster: Aldo-keto reductase; n=28; Bacteria|Rep...   123   1e-26
UniRef50_Q05KR9 Cluster: Benzil reductase; n=5; Bacillales|Rep: ...   123   1e-26
UniRef50_A6RKL9 Cluster: Putative uncharacterized protein; n=3; ...   123   2e-26
UniRef50_Q03XK0 Cluster: Aldo/keto reductase of diketogulonate r...   122   2e-26
UniRef50_Q7R2T6 Cluster: GLP_291_56367_57278; n=1; Giardia lambl...   122   2e-26
UniRef50_UPI00006CD296 Cluster: oxidoreductase, aldo/keto reduct...   122   3e-26
UniRef50_Q8F1G4 Cluster: Aldehyde reductase; n=8; Bacteria|Rep: ...   122   3e-26
UniRef50_A6NPD6 Cluster: Putative uncharacterized protein; n=3; ...   121   6e-26
UniRef50_Q7XY49 Cluster: Mannose 6-phosphate reductase; n=1; Gri...   121   6e-26
UniRef50_Q4PDR0 Cluster: Putative uncharacterized protein; n=1; ...   121   6e-26
UniRef50_Q6NII7 Cluster: Putative oxidoreductase; n=2; Corynebac...   120   1e-25
UniRef50_A0JRJ3 Cluster: 2,5-didehydrogluconate reductase; n=3; ...   120   1e-25
UniRef50_A7CUW0 Cluster: 2,5-didehydrogluconate reductase; n=6; ...   120   1e-25
UniRef50_Q11BF8 Cluster: Aldo/keto reductase; n=12; Bacteria|Rep...   119   2e-25
UniRef50_A6LZ55 Cluster: 2,5-didehydrogluconate reductase; n=1; ...   119   2e-25
UniRef50_UPI00015B5BD7 Cluster: PREDICTED: similar to aldo-keto ...   119   2e-25
UniRef50_Q68ST9 Cluster: Reductase AKOR2; n=2; Pleurotus djamor|...   119   2e-25
UniRef50_P06632 Cluster: 2,5-diketo-D-gluconic acid reductase A;...   119   2e-25
UniRef50_Q83N50 Cluster: 2,5-diketo-D-gluconic acid reductase; n...   118   3e-25
UniRef50_A7BA05 Cluster: Putative uncharacterized protein; n=1; ...   118   4e-25
UniRef50_Q838E0 Cluster: Oxidoreductase, aldo/keto reductase fam...   117   7e-25
UniRef50_Q9ZUJ6 Cluster: T2K10.1 protein; n=16; core eudicotyled...   117   7e-25
UniRef50_A7P424 Cluster: Chromosome chr1 scaffold_5, whole genom...   117   7e-25
UniRef50_A3C1Z7 Cluster: Putative uncharacterized protein; n=2; ...   117   7e-25
UniRef50_Q5HR31 Cluster: Oxidoreductase, aldo/keto reductase fam...   117   1e-24
UniRef50_Q1VRG6 Cluster: YvgN; n=1; Psychroflexus torquis ATCC 7...   117   1e-24
UniRef50_Q4P4P1 Cluster: Putative uncharacterized protein; n=1; ...   117   1e-24
UniRef50_A7ALH6 Cluster: Putative uncharacterized protein; n=1; ...   116   2e-24
UniRef50_A5PDA8 Cluster: Putative oxidoreductase protein; n=1; E...   114   5e-24
UniRef50_A2UAH0 Cluster: Aldo/keto reductase; n=1; Bacillus coag...   114   7e-24
UniRef50_Q4PHK0 Cluster: Putative uncharacterized protein; n=1; ...   113   1e-23
UniRef50_Q28P63 Cluster: Aldo/keto reductase; n=4; Rhodobacterac...   112   2e-23
UniRef50_Q17DN1 Cluster: Aldo-keto reductase; n=1; Aedes aegypti...   112   2e-23
UniRef50_Q5FT75 Cluster: Putative 2,5-diketo-D-gluconic acid red...   112   3e-23
UniRef50_Q5FLI5 Cluster: Aldehyde reductase; n=2; Bacteria|Rep: ...   112   3e-23
UniRef50_Q24C22 Cluster: Oxidoreductase, aldo/keto reductase fam...   111   5e-23
UniRef50_Q7NB44 Cluster: ARA1; n=3; Firmicutes|Rep: ARA1 - Mycop...   111   6e-23
UniRef50_Q03X85 Cluster: Aldo/keto reductase of diketogulonate r...   110   9e-23
UniRef50_UPI00006CCCD7 Cluster: oxidoreductase, aldo/keto reduct...   110   1e-22
UniRef50_Q890A0 Cluster: Oxidoreductase; n=6; Lactobacillales|Re...   110   1e-22
UniRef50_Q1RFP0 Cluster: 2,5-diketo-D-gluconic acid reductase A;...   109   2e-22
UniRef50_Q5TNP1 Cluster: ENSANGP00000029046; n=2; Culicidae|Rep:...   109   3e-22
UniRef50_A0JRJ6 Cluster: Aldo/keto reductase; n=2; Micrococcinea...   108   3e-22
UniRef50_A0AWM8 Cluster: Aldo/keto reductase; n=4; Actinomycetal...   108   5e-22
UniRef50_Q235V6 Cluster: Oxidoreductase, aldo/keto reductase fam...   107   8e-22
UniRef50_A2QB88 Cluster: Contig An01c0460, complete genome. prec...   107   8e-22
UniRef50_Q8ET73 Cluster: 2,5-diketo-D-gluconate reductase; n=12;...   107   1e-21
UniRef50_Q043M4 Cluster: Aldo/keto reductase of diketogulonate r...   107   1e-21
UniRef50_A0JX62 Cluster: 2,5-didehydrogluconate reductase; n=9; ...   106   1e-21
UniRef50_Q929C8 Cluster: Lin2349 protein; n=12; Listeria|Rep: Li...   106   2e-21
UniRef50_Q5FKI1 Cluster: Reductase-dehydrogenase; n=1; Lactobaci...   106   2e-21
UniRef50_A5AD50 Cluster: Putative uncharacterized protein; n=3; ...   106   2e-21
UniRef50_O13848 Cluster: NADH/NADPH dependent indole-3-acetaldeh...   106   2e-21
UniRef50_UPI00006CA3CB Cluster: oxidoreductase, aldo/keto reduct...   105   2e-21
UniRef50_UPI0000DB6EE9 Cluster: PREDICTED: similar to C35D10.6; ...   105   3e-21
UniRef50_Q4JX70 Cluster: Putative oxidoreductase; n=1; Corynebac...   105   3e-21
UniRef50_P82125 Cluster: 1,5-anhydro-D-fructose reductase; n=1; ...   105   3e-21
UniRef50_Q17568 Cluster: Putative uncharacterized protein; n=1; ...   105   4e-21
UniRef50_Q927E1 Cluster: Lin2848 protein; n=13; Listeria|Rep: Li...   104   6e-21
UniRef50_Q5BLA6 Cluster: Zgc:110782; n=2; Danio rerio|Rep: Zgc:1...   104   7e-21
UniRef50_Q18483 Cluster: Putative uncharacterized protein; n=2; ...   104   7e-21
UniRef50_Q568D7 Cluster: Zgc:110366; n=7; Euteleostomi|Rep: Zgc:...   103   1e-20
UniRef50_Q7WSY4 Cluster: Putative aldo-keto reductase; n=1; Prop...   103   1e-20
UniRef50_A3VHZ9 Cluster: Oxidoreductase; n=1; Rhodobacterales ba...   103   1e-20
UniRef50_Q572D2 Cluster: Aldo-keto reductase, putative; n=1; Phy...   103   1e-20
UniRef50_Q88TV9 Cluster: Oxidoreductase; n=4; Lactobacillus|Rep:...   103   2e-20
UniRef50_Q3E9M9 Cluster: Uncharacterized protein At5g01670.2; n=...   103   2e-20
UniRef50_Q9A2X8 Cluster: Oxidoreductase, aldo/keto reductase fam...   102   2e-20
UniRef50_Q54NR2 Cluster: Aldo-keto reductase; n=3; Dictyostelium...   102   3e-20
UniRef50_A5VK30 Cluster: 2,5-didehydrogluconate reductase; n=2; ...   101   4e-20
UniRef50_P47137 Cluster: Probable oxidoreductase YJR096W; n=8; S...   101   4e-20
UniRef50_Q02198 Cluster: Morphine 6-dehydrogenase; n=5; Bacteria...   101   4e-20
UniRef50_P91997 Cluster: Putative uncharacterized protein; n=4; ...   101   5e-20
UniRef50_A4FEB9 Cluster: 2,5-diketo-D-gluconic acid reductase; n...   101   7e-20
UniRef50_Q5XJM7 Cluster: Zgc:101765; n=5; Eumetazoa|Rep: Zgc:101...   100   1e-19
UniRef50_A1UEC5 Cluster: 2,5-didehydrogluconate reductase; n=20;...   100   1e-19
UniRef50_A5BF24 Cluster: Putative uncharacterized protein; n=1; ...   100   1e-19
UniRef50_A3UJS6 Cluster: Oxidoreductase; n=3; Alphaproteobacteri...    99   2e-19
UniRef50_Q6CEJ0 Cluster: Yarrowia lipolytica chromosome B of str...    99   2e-19
UniRef50_Q7VHE1 Cluster: Putative uncharacterized protein; n=1; ...    99   3e-19
UniRef50_Q0SFM4 Cluster: Probable 2,5-didehydrogluconate reducta...    99   3e-19
UniRef50_A6RMS0 Cluster: Putative uncharacterized protein; n=1; ...    98   6e-19
UniRef50_Q4WP69 Cluster: Aldehyde reductase, putative; n=1; Aspe...    97   9e-19
UniRef50_Q0CK00 Cluster: Predicted protein; n=1; Aspergillus ter...    97   9e-19
UniRef50_Q8G7K9 Cluster: Dehydrogenase or reductase protein; n=4...    97   1e-18
UniRef50_A6VNW9 Cluster: Aldo/keto reductase precursor; n=1; Act...    97   1e-18
UniRef50_Q89JN4 Cluster: Oxidoreductase; n=8; Rhizobiales|Rep: O...    97   1e-18
UniRef50_A7RRF6 Cluster: Predicted protein; n=2; Nematostella ve...    96   2e-18
UniRef50_Q6F7K7 Cluster: 2,5-diketo-D-gluconate reductase; n=20;...    96   3e-18
UniRef50_Q9C1X5 Cluster: Xylose and arabinose reductase; n=1; Sc...    96   3e-18
UniRef50_Q2U219 Cluster: Aldo/keto reductase family proteins; n=...    96   3e-18
UniRef50_Q15NA5 Cluster: Aldo/keto reductase; n=2; Gammaproteoba...    95   3e-18
UniRef50_Q8Y463 Cluster: Lmo2592 protein; n=40; Bacteria|Rep: Lm...    95   5e-18
UniRef50_Q8EUH6 Cluster: Oxidoreductase; n=1; Mycoplasma penetra...    95   6e-18
UniRef50_A4YQ04 Cluster: 2,5-diketo-D-gluconate reductase B; n=1...    95   6e-18
UniRef50_Q1DLF1 Cluster: Putative uncharacterized protein; n=1; ...    95   6e-18
UniRef50_A7D761 Cluster: Aldo/keto reductase; n=2; Halobacteriac...    94   8e-18
UniRef50_A3JU52 Cluster: 2,5-diketo-D-gluconic acid reductase A;...    94   1e-17
UniRef50_Q5UX52 Cluster: Oxidoreductase aldo/keto reductase fami...    94   1e-17
UniRef50_Q5B034 Cluster: Putative uncharacterized protein; n=1; ...    93   1e-17
UniRef50_Q4PE96 Cluster: Putative uncharacterized protein; n=1; ...    93   2e-17
UniRef50_Q5FK99 Cluster: Oxidoreductase aldo-keto reductase fami...    93   2e-17
UniRef50_Q927P9 Cluster: Lin2739 protein; n=12; Bacteria|Rep: Li...    92   3e-17
UniRef50_Q14LU6 Cluster: Putative aldo/keto reductase oxidoreduc...    92   3e-17
UniRef50_Q1Q8W8 Cluster: Aldo/keto reductase; n=1; Psychrobacter...    92   4e-17
UniRef50_A5DRJ6 Cluster: Putative uncharacterized protein; n=4; ...    92   4e-17
UniRef50_A6SI80 Cluster: Putative uncharacterized protein; n=1; ...    91   6e-17
UniRef50_Q09632 Cluster: Probable oxidoreductase ZK1290.5; n=2; ...    91   6e-17
UniRef50_Q8EVT8 Cluster: Oxidoreductase-aldo/keto reductase fami...    91   1e-16
UniRef50_Q9X265 Cluster: Oxidoreductase, aldo/keto reductase fam...    90   1e-16
UniRef50_Q9HM42 Cluster: Alcohol dehydrogenase related protein; ...    90   1e-16
UniRef50_Q4V008 Cluster: Oxidoreductase; n=4; Proteobacteria|Rep...    90   2e-16
UniRef50_Q6WGK4 Cluster: Aldose reductase; n=1; Pristionchus pac...    89   2e-16
UniRef50_Q4DJ59 Cluster: Aldo/keto reductase, putative; n=2; Try...    89   2e-16
UniRef50_Q5V6N9 Cluster: Alcohol dehydrogenase; n=2; Halobacteri...    89   2e-16
UniRef50_A5ZYE6 Cluster: Putative uncharacterized protein; n=1; ...    89   3e-16
UniRef50_Q03U37 Cluster: Aldo/keto reductase of diketogulonate r...    89   4e-16
UniRef50_A7BES9 Cluster: Putative uncharacterized protein; n=1; ...    89   4e-16
UniRef50_A3VRL4 Cluster: Putative uncharacterized protein; n=1; ...    88   5e-16
UniRef50_Q5KD52 Cluster: Oxidoreductase, putative; n=1; Filobasi...    88   5e-16
UniRef50_UPI00005A2CCB Cluster: PREDICTED: similar to Aldose red...    87   9e-16
UniRef50_P15339 Cluster: 2,5-diketo-D-gluconic acid reductase B;...    87   1e-15
UniRef50_Q6U5V3 Cluster: Putative uncharacterized protein; n=1; ...    87   2e-15
UniRef50_A2RMU6 Cluster: Oxidoreductase, aldo/keto reductase fam...    87   2e-15
UniRef50_A0L1A2 Cluster: Aldo/keto reductase; n=8; Gammaproteoba...    87   2e-15
UniRef50_Q4WUF7 Cluster: Aldo-keto reductase, putative; n=3; Pez...    87   2e-15
UniRef50_Q11DV1 Cluster: Aldo/keto reductase; n=10; Alphaproteob...    85   5e-15
UniRef50_O14088 Cluster: Xylose and arabinose reductase; n=1; Sc...    85   5e-15
UniRef50_A7D6Q0 Cluster: Aldo/keto reductase; n=1; Halorubrum la...    85   5e-15
UniRef50_P91021 Cluster: Putative uncharacterized protein; n=1; ...    85   6e-15
UniRef50_Q4P1G1 Cluster: Putative uncharacterized protein; n=1; ...    85   6e-15
UniRef50_Q8ZH36 Cluster: 2,5-diketo-D-gluconic acid reductase B;...    85   6e-15
UniRef50_UPI000155CAC7 Cluster: PREDICTED: hypothetical protein;...    84   9e-15
UniRef50_Q7M4N1 Cluster: Dihydrodiol dehydrogenase DD2; n=2; Hom...    70   1e-14
UniRef50_Q8EVS8 Cluster: Oxidoreductase; n=1; Mycoplasma penetra...    83   1e-14
UniRef50_Q5B5R6 Cluster: Putative uncharacterized protein; n=1; ...    83   1e-14
UniRef50_Q2BBN7 Cluster: YvgN; n=1; Bacillus sp. NRRL B-14911|Re...    83   2e-14
UniRef50_Q1M4Z6 Cluster: Putative aldo-keto reductase/oxidase; n...    83   2e-14
UniRef50_A7TLC4 Cluster: Putative uncharacterized protein; n=1; ...    83   2e-14
UniRef50_Q00XM4 Cluster: Aldo/keto reductase family proteins; n=...    83   3e-14
UniRef50_A6PR52 Cluster: Aldo/keto reductase; n=1; Victivallis v...    82   5e-14
UniRef50_A3WP89 Cluster: Aldo/keto reductase; n=1; Idiomarina ba...    82   5e-14
UniRef50_A3T261 Cluster: Putative uncharacterized protein; n=1; ...    82   5e-14
UniRef50_Q5K8C5 Cluster: Aldo-keto reductase, putative; n=1; Fil...    82   5e-14
UniRef50_Q3CZS2 Cluster: Oxidoreductase, aldo/keto reductase fam...    81   8e-14
UniRef50_Q5V398 Cluster: Oxidoreductase aldo/keto reductase fami...    81   8e-14
UniRef50_Q4Q973 Cluster: Aldo/keto reductase, putative; n=3; Lei...    81   1e-13
UniRef50_Q6L139 Cluster: 2,5-diketo-D-gluconic acid reductase; n...    81   1e-13
UniRef50_Q5UYI9 Cluster: Oxidoreductase; n=1; Haloarcula marismo...    81   1e-13
UniRef50_Q5NLW3 Cluster: Putative oxidoreductase; n=1; Zymomonas...    80   1e-13
UniRef50_Q5V663 Cluster: Aldehyde reductase; n=6; Halobacteriace...    80   1e-13
UniRef50_Q2H7A8 Cluster: Putative uncharacterized protein; n=1; ...    79   2e-13
UniRef50_Q76L37 Cluster: Conjugated polyketone reductase C1; n=3...    79   3e-13
UniRef50_A1CAM7 Cluster: Aldo-keto reductase, putative; n=9; Dik...    79   4e-13
UniRef50_Q9P734 Cluster: Related to 2, 5-diketo-D-gluconic acid ...    78   6e-13
UniRef50_Q68A33 Cluster: Aldo-keto reductase 1a; n=1; Ciona inte...    78   7e-13
UniRef50_Q21274 Cluster: Putative uncharacterized protein; n=1; ...    77   1e-12
UniRef50_Q9P6D3 Cluster: Related to aldo-keto reductase YPR1; n=...    77   1e-12
UniRef50_Q75E75 Cluster: ABL209Cp; n=1; Eremothecium gossypii|Re...    77   1e-12
UniRef50_A4R217 Cluster: Putative uncharacterized protein; n=1; ...    75   5e-12
UniRef50_Q979I4 Cluster: Aldo / keto reductase; n=3; Archaea|Rep...    75   5e-12
UniRef50_Q59Z55 Cluster: Potential aldo/keto reductase; n=6; Sac...    75   7e-12
UniRef50_Q4JCC1 Cluster: 2,5-diketo-D-gluconic acid reductase A;...    75   7e-12
UniRef50_Q1PV10 Cluster: Putative uncharacterized protein; n=1; ...    74   1e-11
UniRef50_Q013C5 Cluster: Glycerol dehydrogenase, putative; n=2; ...    73   2e-11
UniRef50_A7SGW6 Cluster: Predicted protein; n=1; Nematostella ve...    73   2e-11
UniRef50_Q07551 Cluster: NADPH-dependent alpha-keto amide reduct...    73   2e-11
UniRef50_Q61U89 Cluster: Putative uncharacterized protein CBG054...    73   3e-11
UniRef50_A7RUA2 Cluster: Predicted protein; n=1; Nematostella ve...    73   3e-11
UniRef50_Q5KCN9 Cluster: Putative uncharacterized protein; n=1; ...    72   4e-11
UniRef50_Q5FHT2 Cluster: Aldehyde reductase; n=4; Lactobacillus|...    71   8e-11
UniRef50_A3H9Y8 Cluster: Aldo/keto reductase; n=2; Caldivirga ma...    71   8e-11
UniRef50_UPI000038E317 Cluster: hypothetical protein Faci_030017...    70   2e-10
UniRef50_Q11B35 Cluster: Aldo/keto reductase; n=1; Mesorhizobium...    70   2e-10
UniRef50_Q9V2P1 Cluster: Myo-inositol degradation; n=5; Archaea|...    70   2e-10
UniRef50_Q5KKZ8 Cluster: Aldo-keto reductase, putative; n=2; Fil...    69   3e-10
UniRef50_A6QVW8 Cluster: Predicted protein; n=1; Ajellomyces cap...    69   5e-10
UniRef50_Q97U17 Cluster: Oxidoreductase, aldo/keto reductase fam...    68   8e-10
UniRef50_A7D7K7 Cluster: Aldo/keto reductase; n=1; Halorubrum la...    68   8e-10
UniRef50_A7D6I8 Cluster: Aldo/keto reductase; n=1; Halorubrum la...    68   8e-10
UniRef50_A5BYJ4 Cluster: Putative uncharacterized protein; n=1; ...    67   1e-09
UniRef50_Q6CGE9 Cluster: Similar to sp|P47137 Saccharomyces cere...    67   1e-09
UniRef50_Q4WI64 Cluster: Aldehyde reductase, putative; n=22; Pez...    67   1e-09
UniRef50_Q0DHN0 Cluster: Os05g0456200 protein; n=2; Oryza sativa...    66   2e-09
UniRef50_Q89RG2 Cluster: Aldo/keto reductase; n=11; Bacteria|Rep...    66   3e-09
UniRef50_P76234 Cluster: Uncharacterized protein yeaE; n=39; Bac...    66   3e-09
UniRef50_A7PNT1 Cluster: Chromosome chr8 scaffold_23, whole geno...    65   4e-09
UniRef50_Q6CWB9 Cluster: Similarities with sp|Q12458 Saccharomyc...    65   4e-09
UniRef50_A7EW94 Cluster: Putative uncharacterized protein; n=1; ...    65   4e-09
UniRef50_A1RB46 Cluster: 2,5-diketo-D-gluconate reductase; n=1; ...    65   6e-09
UniRef50_Q97UV9 Cluster: Oxidoreductase; n=1; Sulfolobus solfata...    65   6e-09
UniRef50_Q5V1M9 Cluster: Oxidoreductase aldo/keto reductase fami...    64   7e-09
UniRef50_A1S0T5 Cluster: Aldo/keto reductase; n=2; Thermoprotei|...    64   7e-09
UniRef50_Q16CS5 Cluster: 2,5-diketo-D-gluconic acid reductase B,...    64   1e-08
UniRef50_A7LSN6 Cluster: Putative uncharacterized protein; n=3; ...    64   1e-08
UniRef50_Q7NK63 Cluster: Gll1617 protein; n=1; Gloeobacter viola...    64   1e-08
UniRef50_Q64UK5 Cluster: Aldo/keto reductase family oxidoreducta...    63   2e-08
UniRef50_Q2CAL9 Cluster: 2,5-didehydrogluconate reductase; n=2; ...    63   2e-08
UniRef50_Q14LA8 Cluster: Putative aldo/keto reductase oxidoreduc...    63   2e-08
UniRef50_A2G4I3 Cluster: Oxidoreductase, aldo/keto reductase fam...    63   2e-08
UniRef50_UPI000023DF27 Cluster: hypothetical protein FG07276.1; ...    62   4e-08
UniRef50_A3LWP0 Cluster: Aldo/keto reductase; n=7; Saccharomycet...    62   4e-08
UniRef50_Q97V56 Cluster: Dehydrogenase; n=8; Thermoprotei|Rep: D...    62   4e-08
UniRef50_Q76L36 Cluster: Conjugated polyketone reductase C2; n=1...    62   5e-08
UniRef50_A6R5B4 Cluster: NAD(P)H-dependent D-xylose reductase; n...    61   9e-08
UniRef50_Q0GU15 Cluster: ORF28; n=3; Bacteria|Rep: ORF28 - Lacto...    60   1e-07
UniRef50_Q4Q5X1 Cluster: Aldehyde reductase, putative; n=75; cel...    60   1e-07
UniRef50_UPI0001556575 Cluster: PREDICTED: similar to Aldo-keto ...    60   2e-07
UniRef50_A4IJ00 Cluster: LOC548351 protein; n=1; Xenopus tropica...    60   2e-07
UniRef50_A2WWZ1 Cluster: Putative uncharacterized protein; n=1; ...    60   2e-07
UniRef50_A1CLD1 Cluster: Gamma-cysteine synthetase regulatory su...    59   3e-07
UniRef50_Q64W37 Cluster: 2,5-diketo-D-gluconic acid reductase; n...    59   4e-07
UniRef50_Q8DK16 Cluster: Tlr1054 protein; n=6; Cyanobacteria|Rep...    58   8e-07
UniRef50_Q5ZTU6 Cluster: D-xylose reductase III; n=5; Legionella...    57   1e-06
UniRef50_Q9USV2 Cluster: Xylose and arabinose reductase; n=2; Sc...    57   1e-06
UniRef50_Q55ML8 Cluster: Putative uncharacterized protein; n=2; ...    57   1e-06
UniRef50_Q55FL2 Cluster: Putative uncharacterized protein; n=1; ...    56   2e-06
UniRef50_Q4WF80 Cluster: Glycerol dehydrogenase (GCY1), putative...    56   2e-06
UniRef50_Q8ZU65 Cluster: Aldo-keto reductase, putative; n=4; The...    56   2e-06
UniRef50_Q03BE0 Cluster: Aldo/keto reductase family enzyme; n=5;...    56   3e-06
UniRef50_A7HEV1 Cluster: Aldo/keto reductase; n=13; Bacteria|Rep...    56   3e-06
UniRef50_Q18903 Cluster: Putative uncharacterized protein C56G3....    56   3e-06
UniRef50_A6QXT4 Cluster: Predicted protein; n=1; Ajellomyces cap...    56   3e-06
UniRef50_Q5BC40 Cluster: Putative uncharacterized protein; n=1; ...    54   1e-05
UniRef50_A6SUJ2 Cluster: Uncharacterized conserved protein; n=2;...    54   1e-05
UniRef50_Q016B0 Cluster: COG0667: Predicted oxidoreductases; n=4...    54   1e-05
UniRef50_Q9X0R5 Cluster: Oxidoreductase, aldo/keto reductase fam...    53   2e-05
UniRef50_Q8PN61 Cluster: Oxidoreductase; n=5; Proteobacteria|Rep...    53   2e-05
UniRef50_A6BIJ0 Cluster: Putative uncharacterized protein; n=1; ...    53   2e-05
UniRef50_A2FJN9 Cluster: Putative uncharacterized protein; n=4; ...    53   2e-05
UniRef50_Q6L0T3 Cluster: Oxidoreductase; n=2; Thermoplasmatales|...    52   3e-05
UniRef50_Q8YAN3 Cluster: Lmo0084 protein; n=11; Listeria monocyt...    52   6e-05
UniRef50_A7PU13 Cluster: Chromosome chr7 scaffold_31, whole geno...    52   6e-05
UniRef50_Q59ZT1 Cluster: Putative uncharacterized protein; n=1; ...    52   6e-05
UniRef50_Q2H1Q3 Cluster: Putative uncharacterized protein; n=1; ...    51   7e-05
UniRef50_Q5KKC5 Cluster: Putative uncharacterized protein; n=2; ...    51   1e-04
UniRef50_A1RA11 Cluster: Oxidoreductase, aldo/keto reductase fam...    50   2e-04
UniRef50_Q8UIN0 Cluster: Oxidoreductase; n=3; Alphaproteobacteri...    50   2e-04
UniRef50_Q21EY6 Cluster: Aldo/keto reductase; n=1; Saccharophagu...    50   2e-04
UniRef50_P0A9T5 Cluster: Protein tas; n=88; Bacteria|Rep: Protei...    50   2e-04
UniRef50_UPI0000DAE567 Cluster: hypothetical protein Rgryl_01000...    49   3e-04
UniRef50_UPI000023DA24 Cluster: hypothetical protein FG10036.1; ...    49   3e-04
UniRef50_Q8EUX1 Cluster: Aldo/keto reductase family oxidoreducta...    49   3e-04
UniRef50_Q87SA8 Cluster: Oxidoreductase Tas, aldo/keto reductase...    49   3e-04
UniRef50_Q660Z5 Cluster: Aldose reductase, putative; n=3; Borrel...    49   3e-04
UniRef50_A2UBC7 Cluster: Aldo/keto reductase; n=3; cellular orga...    49   3e-04
UniRef50_Q1IPE6 Cluster: Aldo/keto reductase; n=21; Bacteria|Rep...    49   4e-04
UniRef50_UPI000023DAA9 Cluster: hypothetical protein FG00321.1; ...    48   5e-04
UniRef50_Q2JB77 Cluster: Aldo/keto reductase; n=1; Frankia sp. C...    48   5e-04
UniRef50_Q1U6R9 Cluster: Aldo/keto reductase; n=25; Bacilli|Rep:...    48   5e-04
UniRef50_A7RPK2 Cluster: Predicted protein; n=1; Nematostella ve...    48   5e-04
UniRef50_A3DNU7 Cluster: Aldo/keto reductase; n=3; Desulfurococc...    48   5e-04
UniRef50_UPI00005F9591 Cluster: COG0656: Aldo/keto reductases, r...    48   7e-04
UniRef50_Q6GIV4 Cluster: Aldo/keto reductase family protein; n=1...    48   7e-04
UniRef50_A7HAM2 Cluster: Aldo/keto reductase; n=9; cellular orga...    48   7e-04
UniRef50_Q82JL9 Cluster: Putative oxidoreductase; n=2; Streptomy...    48   0.001
UniRef50_Q2SL81 Cluster: Predicted oxidoreductase; n=10; Bacteri...    48   0.001
UniRef50_Q0UQ60 Cluster: Putative uncharacterized protein; n=1; ...    48   0.001
UniRef50_Q67NQ1 Cluster: Oxidoreductase; n=1; Symbiobacterium th...    47   0.001
UniRef50_A4M6J9 Cluster: Aldo/keto reductase; n=1; Petrotoga mob...    47   0.001
UniRef50_P80874 Cluster: General stress protein 69; n=16; cellul...    47   0.001
UniRef50_Q2JHT1 Cluster: Aldo/keto reductase Tas; n=25; cellular...    47   0.002
UniRef50_Q93KW0 Cluster: Putative oxidoreductase; n=1; Streptomy...    47   0.002
UniRef50_A6W292 Cluster: Aldo/keto reductase; n=9; Bacteria|Rep:...    47   0.002
UniRef50_A1ZPI5 Cluster: Oxidoreductase; n=1; Microscilla marina...    47   0.002
UniRef50_A0YSM3 Cluster: Probable oxidoreductase; n=1; Lyngbya s...    47   0.002
UniRef50_P93818 Cluster: F19P19.12 protein; n=4; Arabidopsis tha...    47   0.002
UniRef50_Q9C2J8 Cluster: Related to D-xylose reductase II, III p...    47   0.002
UniRef50_Q7D001 Cluster: AGR_C_2023p; n=14; Proteobacteria|Rep: ...    46   0.002
UniRef50_Q1IQ78 Cluster: Aldo/keto reductase; n=1; Acidobacteria...    46   0.002
UniRef50_A1B5W4 Cluster: Aldo/keto reductase; n=1; Paracoccus de...    46   0.002
UniRef50_A0LJ47 Cluster: Aldo/keto reductase; n=1; Syntrophobact...    46   0.002
UniRef50_A4QYG8 Cluster: Putative uncharacterized protein; n=1; ...    46   0.002
UniRef50_A0RWV1 Cluster: Oxidoreductase; n=4; Thermoprotei|Rep: ...    37   0.003
UniRef50_A6WAE5 Cluster: Aldo/keto reductase; n=1; Kineococcus r...    46   0.003
UniRef50_A5VEK4 Cluster: Aldo/keto reductase; n=5; Bacteria|Rep:...    46   0.003
UniRef50_A0QHX8 Cluster: General stress protein 69; n=2; Mycobac...    46   0.003
UniRef50_P46905 Cluster: Uncharacterized oxidoreductase yccK; n=...    46   0.003
UniRef50_UPI0000D9C1BD Cluster: PREDICTED: similar to aldo-keto ...    46   0.004
UniRef50_Q98G15 Cluster: Mll3531 protein; n=3; Bacteria|Rep: Mll...    46   0.004
UniRef50_A6X3I0 Cluster: Aldo/keto reductase; n=3; Bacteria|Rep:...    46   0.004
UniRef50_Q872E2 Cluster: Related to gamma-glutamylcysteine synth...    46   0.004
UniRef50_Q60BI7 Cluster: Oxidoreductase, aldo/keto reductase fam...    45   0.005
UniRef50_Q11BU4 Cluster: Aldo/keto reductase; n=11; Proteobacter...    45   0.005
UniRef50_A0QWF1 Cluster: Aldo/keto reductase; n=1; Mycobacterium...    45   0.005
UniRef50_P40690 Cluster: Aldo-keto reductase; n=4; Piroplasmida|...    45   0.005
UniRef50_Q88SS2 Cluster: Oxidoreductase; n=13; Firmicutes|Rep: O...    45   0.006
UniRef50_Q81RN9 Cluster: Oxidoreductase, aldo/keto reductase fam...    45   0.006
UniRef50_A7CVG9 Cluster: Aldo/keto reductase; n=1; Opitutaceae b...    45   0.006
UniRef50_A1RAH7 Cluster: Oxidoreductase, aldo/keto reductase fam...    45   0.006
UniRef50_A0K1H5 Cluster: Aldo/keto reductase; n=6; Actinomycetal...    45   0.006
UniRef50_Q2BBT9 Cluster: Probable oxidoreductase protein; n=2; B...    44   0.008
UniRef50_Q0LP88 Cluster: Aldo/keto reductase; n=4; Bacteria|Rep:...    44   0.008
UniRef50_A7BLU0 Cluster: Aldo/keto reductase family; n=1; Beggia...    44   0.008
UniRef50_Q3I1P2 Cluster: Aldo-keto oxidoreductase; n=6; Bacteria...    44   0.011
UniRef50_Q03I00 Cluster: Aryl-alcohol dehydrogenase related enzy...    44   0.011
UniRef50_UPI00015BB020 Cluster: aldo/keto reductase; n=1; Ignico...    44   0.015
UniRef50_UPI0000447325 Cluster: PREDICTED: similar to aldo-keto ...    44   0.015
UniRef50_A6LWU9 Cluster: Aldo/keto reductase; n=3; Clostridium|R...    44   0.015
UniRef50_O94246 Cluster: Glutamate-cysteine ligase regulatory su...    44   0.015
UniRef50_A7B5J6 Cluster: Putative uncharacterized protein; n=1; ...    43   0.019
UniRef50_UPI0000611A01 Cluster: PREDICTED: similar to MGC80525 p...    43   0.026
UniRef50_A0Q648 Cluster: Aldo/keto reductase family protein; n=1...    43   0.026
UniRef50_Q2H7Q3 Cluster: Putative uncharacterized protein; n=1; ...    43   0.026
UniRef50_A6VXU3 Cluster: Aldo/keto reductase; n=14; Proteobacter...    42   0.034
UniRef50_A5FAZ9 Cluster: Aldo/keto reductase; n=1; Flavobacteriu...    42   0.034
UniRef50_A1GCG3 Cluster: Aldo/keto reductase; n=3; Bacteria|Rep:...    42   0.034
UniRef50_A3H7G3 Cluster: Aldo/keto reductase; n=2; Caldivirga ma...    42   0.034
UniRef50_Q986W6 Cluster: Mlr7180 protein; n=4; Alphaproteobacter...    42   0.045
UniRef50_Q88ZU3 Cluster: Oxidoreductase; n=1; Lactobacillus plan...    42   0.045
UniRef50_Q55493 Cluster: Auxin-induced protein; n=2; Bacteria|Re...    42   0.045
UniRef50_A3U5K6 Cluster: Oxidoreductase, aldo/keto reductase fam...    42   0.045
UniRef50_A0ZMD5 Cluster: Tas; n=1; Nodularia spumigena CCY 9414|...    42   0.045
UniRef50_Q6A7U3 Cluster: Putative oxidoreductase; n=1; Propionib...    42   0.060
UniRef50_Q3WEJ4 Cluster: Aldo/keto reductase; n=9; Bacteria|Rep:...    42   0.060
UniRef50_Q03UP0 Cluster: Aryl-alcohol dehydrogenase family enzym...    42   0.060
UniRef50_A0Y7Y8 Cluster: Aldo/keto reductase; n=1; marine gamma ...    42   0.060
UniRef50_Q034L5 Cluster: Aryl-alcohol dehydrogenase related enzy...    41   0.079
UniRef50_Q01Z07 Cluster: Aldo/keto reductase; n=4; cellular orga...    41   0.079
UniRef50_A7B2Y7 Cluster: Putative uncharacterized protein; n=1; ...    41   0.079
UniRef50_A7T149 Cluster: Predicted protein; n=1; Nematostella ve...    41   0.079
UniRef50_A6SJ74 Cluster: Putative uncharacterized protein; n=1; ...    41   0.079
UniRef50_Q8EVP7 Cluster: Putative oxidoreductase; n=3; Bacteria|...    41   0.10 
UniRef50_Q04TM6 Cluster: Aryl-alcohol dehydrogenase-related oxid...    41   0.10 
UniRef50_A7DS16 Cluster: Aldo/keto reductase; n=1; Candidatus Ni...    41   0.10 
UniRef50_P49261 Cluster: Rho beta-crystallin; n=1; Lepidodactylu...    41   0.10 
UniRef50_Q8Y5Q1 Cluster: Lmo2005 protein; n=34; cellular organis...    40   0.14 
UniRef50_Q82NW9 Cluster: Putative oxidoreductase; n=3; Streptomy...    40   0.14 
UniRef50_Q7NJD8 Cluster: Gll1894 protein; n=5; Bacteria|Rep: Gll...    40   0.14 
UniRef50_Q391C9 Cluster: Aldo/keto reductase; n=10; Proteobacter...    40   0.14 
UniRef50_Q2AI49 Cluster: Aldo/keto reductase; n=1; Halothermothr...    40   0.14 
UniRef50_Q8PVL5 Cluster: Oxidoreductase, ALDO/KETO reductase fam...    40   0.14 
UniRef50_Q7UZ40 Cluster: Putative oxidoreductase-possibly Aldo/k...    40   0.18 
UniRef50_Q2J7H2 Cluster: Aldo/keto reductase; n=16; Bacteria|Rep...    40   0.18 
UniRef50_Q1MJ49 Cluster: Putative general stress protein; n=2; R...    40   0.18 
UniRef50_Q0RGM0 Cluster: Putative aldoketoreductase; n=2; Franki...    40   0.18 
UniRef50_A6AKU1 Cluster: Aldo/keto reductase; n=2; Gammaproteoba...    40   0.18 
UniRef50_A3EV07 Cluster: Putative oxidoreductase; n=1; Leptospir...    40   0.18 
UniRef50_A3LSR5 Cluster: D-threo-aldose 1-dehydrogenase; n=5; Sa...    40   0.18 
UniRef50_Q8EZ83 Cluster: Aldo/keto reductase family protein; n=1...    40   0.24 
UniRef50_Q837G5 Cluster: Oxidoreductase, aldo/keto reductase 2 f...    40   0.24 
UniRef50_Q1FHF4 Cluster: Aldo/keto reductase:4Fe-4S ferredoxin, ...    40   0.24 
UniRef50_A5Z5D1 Cluster: Putative uncharacterized protein; n=4; ...    40   0.24 
UniRef50_A1SGJ5 Cluster: Aldo/keto reductase precursor; n=1; Noc...    40   0.24 
UniRef50_A1RJL6 Cluster: Aldo/keto reductase; n=37; Bacteria|Rep...    40   0.24 
UniRef50_Q27ST7 Cluster: Oxidoreductase; n=2; Eukaryota|Rep: Oxi...    40   0.24 
UniRef50_A0RX58 Cluster: Oxidoreductase; n=1; Cenarchaeum symbio...    40   0.24 
UniRef50_Q98IA6 Cluster: Aryl-alcohol dehydrogenase; n=1; Mesorh...    39   0.32 
UniRef50_Q025S3 Cluster: Aldo/keto reductase precursor; n=1; Sol...    39   0.32 
UniRef50_Q09923 Cluster: Aldo-keto reductase yakc [NADP+]; n=13;...    39   0.32 
UniRef50_Q4TC86 Cluster: Chromosome undetermined SCAF7044, whole...    39   0.42 
UniRef50_Q98JS9 Cluster: Aldo/keto reductase; n=39; Bacteria|Rep...    39   0.42 
UniRef50_Q88TP1 Cluster: Oxidoreductase; n=3; Bacteria|Rep: Oxid...    39   0.42 
UniRef50_Q099T4 Cluster: Oxidoreductase; n=2; Proteobacteria|Rep...    39   0.42 
UniRef50_A6PQ08 Cluster: Aldo/keto reductase precursor; n=1; Vic...    39   0.42 
UniRef50_A6EEC4 Cluster: Putative Norsolorinic acid reductase; n...    39   0.42 
UniRef50_Q97UJ7 Cluster: Oxidoreductase; n=4; Archaea|Rep: Oxido...    39   0.42 
UniRef50_Q2FGN2 Cluster: Oxidoreductase, aldo/keto reductase fam...    38   0.55 
UniRef50_Q4HND9 Cluster: Oxidoreductase, aldo/keto reductase fam...    38   0.55 
UniRef50_Q08VS2 Cluster: Twin-arginine translocation pathway sig...    38   0.55 
UniRef50_Q08P32 Cluster: Aldo/keto reductase; n=3; Proteobacteri...    38   0.55 
UniRef50_A4CIJ8 Cluster: Putative uncharacterized protein; n=2; ...    38   0.55 
UniRef50_A1SLH1 Cluster: Aldo/keto reductase; n=27; Bacteria|Rep...    38   0.55 
UniRef50_Q33BE9 Cluster: Aldo/keto reductase, putative; n=1; Ory...    38   0.55 
UniRef50_Q23TY7 Cluster: Oxidoreductase, aldo/keto reductase fam...    38   0.55 
UniRef50_Q89JX0 Cluster: Oxidoreductase; n=26; Bacteria|Rep: Oxi...    38   0.73 
UniRef50_Q7NH41 Cluster: Gll2696 protein; n=1; Gloeobacter viola...    38   0.73 
UniRef50_Q38Z15 Cluster: Putative aldo/keto reductase; n=2; Bact...    38   0.73 
UniRef50_Q08NK7 Cluster: Aldo/keto reductase; n=1; Stigmatella a...    38   0.73 
UniRef50_A6DNQ2 Cluster: YqkF; n=1; Lentisphaera araneosa HTCC21...    38   0.73 
UniRef50_A1ZSV4 Cluster: Oxidoreductase, aldo/keto reductase fam...    38   0.73 
UniRef50_Q9SAC2 Cluster: T16B5.5 protein; n=23; Magnoliophyta|Re...    38   0.73 
UniRef50_Q97ZZ1 Cluster: Oxidoreductase; n=4; Sulfolobaceae|Rep:...    38   0.73 
UniRef50_A0YC40 Cluster: Putative uncharacterized protein; n=1; ...    38   0.97 
UniRef50_Q1JST0 Cluster: Aldo-keto reductase, putative; n=1; Tox...    38   0.97 
UniRef50_Q1GHE2 Cluster: Aldo/keto reductase; n=8; Alphaproteoba...    37   1.3  
UniRef50_A7HL79 Cluster: Aldo/keto reductase; n=1; Fervidobacter...    37   1.3  
UniRef50_A6C9W8 Cluster: Aldo/keto reductase; n=2; Planctomyceta...    37   1.3  
UniRef50_A0JTR5 Cluster: Aldo/keto reductase; n=2; Actinomycetal...    37   1.3  
UniRef50_A0GDL6 Cluster: Aldo/keto reductase; n=1; Burkholderia ...    37   1.3  
UniRef50_Q5ASJ7 Cluster: Putative uncharacterized protein; n=1; ...    37   1.3  
UniRef50_P76187 Cluster: Oxidoreductase ydhF; n=51; Gammaproteob...    37   1.3  
UniRef50_Q3WFK9 Cluster: Aldo/keto reductase precursor; n=1; Fra...    37   1.7  
UniRef50_Q28MK3 Cluster: Aldo/keto reductase; n=19; Alphaproteob...    37   1.7  
UniRef50_Q11KU9 Cluster: Twin-arginine translocation pathway sig...    37   1.7  

>UniRef50_Q7PCV3 Cluster: ENSANGP00000031808; n=9;
           Endopterygota|Rep: ENSANGP00000031808 - Anopheles
           gambiae str. PEST
          Length = 316

 Score =  276 bits (676), Expect = 1e-72
 Identities = 136/246 (55%), Positives = 159/246 (64%), Gaps = 1/246 (0%)
 Frame = +1

Query: 121 VPVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKT 300
           VP     NG  IP+ G+GTW S PG+V QAVKDAID+GYRHI CA VY NE EVGE I  
Sbjct: 6   VPNAIFKNGNSIPMFGLGTWNSPPGQVAQAVKDAIDVGYRHIDCAHVYQNEHEVGEGIAA 65

Query: 301 KIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDA 480
           KI EGVVKREDLF+TSKLWNTFHRPDLV GA + +L+NL +DYLDLYLIHWP  Y+E   
Sbjct: 66  KIAEGVVKREDLFVTSKLWNTFHRPDLVEGACKTTLQNLKLDYLDLYLIHWPVGYQEGTE 125

Query: 481 IFPTDADGK-IQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPGH 657
           +FP   DGK   FSD DYVDTW  +E LV  GLVR++GVSNFN+KQ+QR+LD A + P  
Sbjct: 126 LFPMGPDGKTFLFSDADYVDTWPEMEKLVDAGLVRNIGVSNFNAKQVQRVLDVARIPPAT 185

Query: 658 *PGRMPSVFKPXAIEAVLRRP*YYDNGVLPRWGXPDRPWAKPGDPHLMEDPKLKEIADRL 837
                        I               P  G P RPW K  DP LM+D  + ++A + 
Sbjct: 186 NQIECHPYLHQSKITTFCAEKGIIVTAYSP-LGSPARPWVKADDPVLMDDATVGQLAKKH 244

Query: 838 GKXAAQ 855
           GK AAQ
Sbjct: 245 GKSAAQ 250



 Score = 49.6 bits (113), Expect = 2e-04
 Identities = 17/33 (51%), Positives = 25/33 (75%)
 Frame = +2

Query: 656 TNQVECHPYLNXKRLKQFCEDRDIMITXYSPXG 754
           TNQ+ECHPYL+  ++  FC ++ I++T YSP G
Sbjct: 185 TNQIECHPYLHQSKITTFCAEKGIIVTAYSPLG 217


>UniRef50_Q2LZ66 Cluster: GA19341-PA; n=2; Endopterygota|Rep:
           GA19341-PA - Drosophila pseudoobscura (Fruit fly)
          Length = 315

 Score =  259 bits (635), Expect = 1e-67
 Identities = 128/251 (50%), Positives = 166/251 (66%), Gaps = 5/251 (1%)
 Frame = +1

Query: 118 SVPVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIK 297
           S P   LS+G  +P++G+GTW+S P  V QAVKDAIDIGYRH  CA +YGNE  VG AI+
Sbjct: 2   STPSFLLSSGRNMPMVGLGTWRSPPEVVAQAVKDAIDIGYRHFDCAHIYGNELHVGVAIR 61

Query: 298 TKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDD 477
            KIQEG+V R++LFITSKLWNTFH+P+LVR A E SLRNL IDYLDLYL+HWP AYK  D
Sbjct: 62  EKIQEGLVTRDELFITSKLWNTFHKPELVRAACETSLRNLGIDYLDLYLMHWPMAYKSGD 121

Query: 478 AIFPTDAD-GKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPG 654
            ++PT  D GK  F D+DY+DTWKA+E LV  GLV ++GVSNFN KQ+ R+L  A +KP 
Sbjct: 122 NLYPTCPDTGKAVFEDIDYLDTWKAMEDLVDSGLVNAIGVSNFNEKQINRLLCLAKLKPV 181

Query: 655 H*PGRMPSVFKPXAIEAVLRRP*YYDNGV----LPRWGXPDRPWAKPGDPHLMEDPKLKE 822
                     +  ++  +      YDN +        G    P+ KPG   L+++P +  
Sbjct: 182 MLQIECHPYLRQKSLITLC-----YDNAIGVTAYSSLGSGHTPYEKPGSYPLLQNPIIVS 236

Query: 823 IADRLGKXAAQ 855
           +A++ G+  AQ
Sbjct: 237 VAEKYGRTPAQ 247



 Score = 38.3 bits (85), Expect = 0.55
 Identities = 16/31 (51%), Positives = 18/31 (58%)
 Frame = +2

Query: 662 QVECHPYLNXKRLKQFCEDRDIMITXYSPXG 754
           Q+ECHPYL  K L   C D  I +T YS  G
Sbjct: 184 QIECHPYLRQKSLITLCYDNAIGVTAYSSLG 214


>UniRef50_P45376 Cluster: Aldose reductase; n=21; Bilateria|Rep:
           Aldose reductase - Mus musculus (Mouse)
          Length = 316

 Score =  257 bits (630), Expect = 5e-67
 Identities = 126/243 (51%), Positives = 164/243 (67%), Gaps = 3/243 (1%)
 Frame = +1

Query: 136 LSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQEG 315
           L+NG K+P +G+GTWKS PG+VT+AVK AID+GYRHI CA VY NEKEVG A++ K++E 
Sbjct: 7   LNNGTKMPTLGLGTWKSPPGQVTEAVKVAIDLGYRHIDCAQVYQNEKEVGVALQEKLKEQ 66

Query: 316 VVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTD 495
           VVKR+DLFI SKLW TFH   +V+GA + +L +L +DYLDLYLIHWP  +K     FP D
Sbjct: 67  VVKRQDLFIVSKLWCTFHDKSMVKGAFQKTLSDLQLDYLDLYLIHWPTGFKPGPDYFPLD 126

Query: 496 ADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPGH*PGRMP 675
           A G +  SD D+VDTW A+E LV  GLV+++GVSNFN  Q++RIL+   +K  + P    
Sbjct: 127 ASGNVIPSDTDFVDTWTAMEQLVDEGLVKTIGVSNFNPLQIERILNKPGLK--YKPAVNQ 184

Query: 676 SVFKPXAIEAVLRRP*YYDNGVLPRW---GXPDRPWAKPGDPHLMEDPKLKEIADRLGKX 846
               P   +  L    +    V+  +   G PDRPWAKP DP L+EDP++K IA +  K 
Sbjct: 185 IECHPYLTQEKLIEYCHSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAKYNKT 244

Query: 847 AAQ 855
            AQ
Sbjct: 245 TAQ 247



 Score = 47.2 bits (107), Expect = 0.001
 Identities = 16/32 (50%), Positives = 24/32 (75%)
 Frame = +2

Query: 659 NQVECHPYLNXKRLKQFCEDRDIMITXYSPXG 754
           NQ+ECHPYL  ++L ++C  + I++T YSP G
Sbjct: 183 NQIECHPYLTQEKLIEYCHSKGIVVTAYSPLG 214


>UniRef50_P15121 Cluster: Aldose reductase; n=72; Eumetazoa|Rep:
           Aldose reductase - Homo sapiens (Human)
          Length = 316

 Score =  249 bits (609), Expect = 2e-64
 Identities = 122/243 (50%), Positives = 162/243 (66%), Gaps = 3/243 (1%)
 Frame = +1

Query: 136 LSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQEG 315
           L+NGAK+P++G+GTWKS PG+VT+AVK AID+GYRHI CA VY NE EVG AI+ K++E 
Sbjct: 7   LNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLREQ 66

Query: 316 VVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTD 495
           VVKRE+LFI SKLW T+H   LV+GA + +L +L +DYLDLYLIHWP  +K     FP D
Sbjct: 67  VVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFPLD 126

Query: 496 ADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPGH*PGRMP 675
             G +  SD + +DTW A+E LV  GLV+++G+SNFN  Q++ IL+   +K  + P    
Sbjct: 127 ESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLK--YKPAVNQ 184

Query: 676 SVFKPXAIEAVLRRP*YYDNGVLPRW---GXPDRPWAKPGDPHLMEDPKLKEIADRLGKX 846
               P   +  L +       V+  +   G PDRPWAKP DP L+EDP++K IA +  K 
Sbjct: 185 IECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAKHNKT 244

Query: 847 AAQ 855
            AQ
Sbjct: 245 TAQ 247



 Score = 49.2 bits (112), Expect = 3e-04
 Identities = 17/32 (53%), Positives = 25/32 (78%)
 Frame = +2

Query: 659 NQVECHPYLNXKRLKQFCEDRDIMITXYSPXG 754
           NQ+ECHPYL  ++L Q+C+ + I++T YSP G
Sbjct: 183 NQIECHPYLTQEKLIQYCQSKGIVVTAYSPLG 214


>UniRef50_Q8CI22 Cluster: 2310005E10Rik protein; n=30;
           Tetrapoda|Rep: 2310005E10Rik protein - Mus musculus
           (Mouse)
          Length = 316

 Score =  243 bits (595), Expect = 9e-63
 Identities = 124/244 (50%), Positives = 160/244 (65%), Gaps = 3/244 (1%)
 Frame = +1

Query: 133 TLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQE 312
           TL  GAK+P++G+GTWKS P +V +AVK AID GYRHI CA+VY NE EVGEAI+ KIQE
Sbjct: 6   TLLTGAKMPIVGLGTWKSPPAKVREAVKVAIDAGYRHIDCAYVYQNESEVGEAIQEKIQE 65

Query: 313 GVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPT 492
             VKREDLFI SKLW+TF    LV+ A + +L +L +DYLDLYLIHWPQ ++  +   PT
Sbjct: 66  KAVKREDLFIVSKLWSTFFEKSLVKKAFQNTLSDLKLDYLDLYLIHWPQGFQSGNVFLPT 125

Query: 493 DADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPGH*PGRM 672
           D  G I  S   ++D W+A+E LV  GLV++LGVSNFN  Q++R+L+   +K  H P   
Sbjct: 126 DDKGSILSSKYTFLDAWEAMEELVDQGLVKALGVSNFNHFQIERLLNKPGLK--HKPVTN 183

Query: 673 PSVFKPXAIEAVLRRP*YYDNGVLPRW---GXPDRPWAKPGDPHLMEDPKLKEIADRLGK 843
                P   +  L +  +     +  +   G PDRP AKP DP L+E PK+KEIA +  K
Sbjct: 184 QVECHPYLTQEKLTQYCHSKGITITAYSPLGSPDRPSAKPEDPLLLEIPKIKEIAAKHKK 243

Query: 844 XAAQ 855
            AAQ
Sbjct: 244 TAAQ 247


>UniRef50_Q9VTL0 Cluster: CG6083-PA; n=4; Diptera|Rep: CG6083-PA -
           Drosophila melanogaster (Fruit fly)
          Length = 322

 Score =  241 bits (589), Expect = 5e-62
 Identities = 122/252 (48%), Positives = 161/252 (63%), Gaps = 6/252 (2%)
 Frame = +1

Query: 118 SVPVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIK 297
           S P   LSNG  +P++G+GTW+S P  VTQAVKDAIDIGYRH  CA +YGNE +VG A++
Sbjct: 2   STPNFLLSNGKNMPMLGLGTWRSPPEVVTQAVKDAIDIGYRHFDCAHIYGNEAQVGAALR 61

Query: 298 TKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKE-D 474
            K+ EGVV R++LFITSKLWNT H+PDLVR A E S+RNL + YL+LYL+HWP AYK   
Sbjct: 62  EKMDEGVVTRDELFITSKLWNTHHKPDLVRPACETSIRNLGVKYLNLYLMHWPMAYKSGS 121

Query: 475 DAIFPTDAD-GKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKP 651
           D ++PT  D  K  F D+DYVDTW+A+E LV  GL +++GVSNFN +Q+ R+L  A +KP
Sbjct: 122 DNLYPTCPDTNKAAFEDIDYVDTWRAMENLVDEGLCQAIGVSNFNEQQMNRLLSVAKLKP 181

Query: 652 GH*PGRMPSVFKPXAIEAVLRRP*YYDNGVLPR----WGXPDRPWAKPGDPHLMEDPKLK 819
                          +  +      YDN +        G    P+ KPG   L++ P + 
Sbjct: 182 VVLQIECHPYLSQKPLITLC-----YDNAIAVTAYSCLGSGHTPYEKPGAYPLLQHPTIL 236

Query: 820 EIADRLGKXAAQ 855
            IA++  + AAQ
Sbjct: 237 AIAEKYERTAAQ 248



 Score = 38.7 bits (86), Expect = 0.42
 Identities = 17/34 (50%), Positives = 20/34 (58%)
 Frame = +2

Query: 653 VTNQVECHPYLNXKRLKQFCEDRDIMITXYSPXG 754
           V  Q+ECHPYL+ K L   C D  I +T YS  G
Sbjct: 182 VVLQIECHPYLSQKPLITLCYDNAIAVTAYSCLG 215


>UniRef50_UPI00015B56A2 Cluster: PREDICTED: similar to GA10458-PA;
           n=2; Nasonia vitripennis|Rep: PREDICTED: similar to
           GA10458-PA - Nasonia vitripennis
          Length = 569

 Score =  227 bits (556), Expect = 5e-58
 Identities = 108/244 (44%), Positives = 158/244 (64%)
 Frame = +1

Query: 121 VPVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKT 300
           VP  T ++G K+P+IG+GT+ SKPGEV +AVK AI++GYRH+  AF Y NEKE+G AI+ 
Sbjct: 3   VPTVTFNDGYKMPMIGLGTFLSKPGEVAEAVKYAIEVGYRHVDTAFFYENEKEIGSAIRE 62

Query: 301 KIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDA 480
           KI +G +KRED+F+T+KLW   H+ D V  A + SL NL  DY+DL+L+HWP A+K  DA
Sbjct: 63  KINDGTIKREDIFVTTKLWCNSHKEDEVVPACKKSLENLGFDYIDLFLVHWPFAFKSGDA 122

Query: 481 IFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPGH* 660
           + P DA GKI+FSD DY++TWK +E     GL RS+G+SNFNS+Q+ R+L +A +KP + 
Sbjct: 123 LTPRDAAGKIEFSDTDYLETWKGMEECKRQGLARSIGLSNFNSEQIARLLSSAKIKPVNN 182

Query: 661 PGRMPSVFKPXAIEAVLRRP*YYDNGVLPRWGXPDRPWAKPGDPHLMEDPKLKEIADRLG 840
              +        +    ++      G  P      RP  + G  +L ++P+++++A +  
Sbjct: 183 QVEVTMNLNQKPLIEFCKKHEITVTGFSPL----GRPGNRHGIQNLWDEPQIQKLAQKYK 238

Query: 841 KXAA 852
           K  A
Sbjct: 239 KTPA 242



 Score =  150 bits (364), Expect = 9e-35
 Identities = 83/208 (39%), Positives = 121/208 (58%), Gaps = 1/208 (0%)
 Frame = +1

Query: 235 YRHIXCAFVYGNEKEVGEAIKTKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRN 414
           YRHI  A++Y NEK +G AI+ KI++G VKREDLF+T+KL    H+   V  A + SL +
Sbjct: 301 YRHIDTAYLYDNEKYIGNAIREKIKDGTVKREDLFVTTKLSYYAHKESEVVPACKQSLND 360

Query: 415 LNIDYLDLYLIHWP-QAYKEDDAIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLG 591
           L +DY+DLYLIHWP + Y   +     +A GK+  SD DY++TWK +E     GL RS+G
Sbjct: 361 LGLDYIDLYLIHWPIRRYFRHN----KNASGKLLLSDTDYLETWKGMEECKRQGLARSIG 416

Query: 592 VSNFNSKQLQRILDNASVKPGH*PGRMPSVFKPXAIEAVLRRP*YYDNGVLPRWGXPDRP 771
           VSNFNS+Q+ R+L+ A +KP +    +       A+    ++      G  P      RP
Sbjct: 417 VSNFNSEQITRLLEAAKIKPVNNQVEVSLKLNQKALIEFCKKHDITVTGYSPL----GRP 472

Query: 772 WAKPGDPHLMEDPKLKEIADRLGKXAAQ 855
             + G  +  +DP ++E+  + GK  AQ
Sbjct: 473 GNRYGITNAWDDPIIQELVKKYGKTPAQ 500



 Score = 35.5 bits (78), Expect = 3.9
 Identities = 16/34 (47%), Positives = 21/34 (61%)
 Frame = +2

Query: 653 VTNQVECHPYLNXKRLKQFCEDRDIMITXYSPXG 754
           V NQVE    LN K L +FC+  +I +T +SP G
Sbjct: 180 VNNQVEVTMNLNQKPLIEFCKKHEITVTGFSPLG 213


>UniRef50_P14550 Cluster: Alcohol dehydrogenase [NADP+]; n=44;
           Bilateria|Rep: Alcohol dehydrogenase [NADP+] - Homo
           sapiens (Human)
          Length = 325

 Score =  226 bits (553), Expect = 1e-57
 Identities = 112/241 (46%), Positives = 152/241 (63%), Gaps = 1/241 (0%)
 Frame = +1

Query: 136 LSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQEG 315
           L  G K+P+IG+GTWKS+PG+V  AVK A+ +GYRHI CA +YGNE E+GEA+K  +  G
Sbjct: 8   LHTGQKMPLIGLGTWKSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALKEDVGPG 67

Query: 316 -VVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPT 492
             V RE+LF+TSKLWNT H P+ V  AL  +L +L ++YLDLYL+HWP A++  D  FP 
Sbjct: 68  KAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDNPFPK 127

Query: 493 DADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPGH*PGRM 672
           +ADG I +    Y +TWKALE LV  GLV++LG+SNFNS+Q+  IL  ASV+P       
Sbjct: 128 NADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASVRPAVLQVEC 187

Query: 673 PSVFKPXAIEAVLRRP*YYDNGVLPRWGXPDRPWAKPGDPHLMEDPKLKEIADRLGKXAA 852
                   + A  +          P  G  DR W  P +P L+E+P +  +A++ G+  A
Sbjct: 188 HPYLAQNELIAHCQARGLEVTAYSP-LGSSDRAWRDPDEPVLLEEPVVLALAEKYGRSPA 246

Query: 853 Q 855
           Q
Sbjct: 247 Q 247



 Score = 39.5 bits (88), Expect = 0.24
 Identities = 16/31 (51%), Positives = 19/31 (61%)
 Frame = +2

Query: 662 QVECHPYLNXKRLKQFCEDRDIMITXYSPXG 754
           QVECHPYL    L   C+ R + +T YSP G
Sbjct: 184 QVECHPYLAQNELIAHCQARGLEVTAYSPLG 214


>UniRef50_Q9NAI5 Cluster: Putative uncharacterized protein; n=3;
           Caenorhabditis|Rep: Putative uncharacterized protein -
           Caenorhabditis elegans
          Length = 316

 Score =  218 bits (533), Expect = 3e-55
 Identities = 107/240 (44%), Positives = 144/240 (60%)
 Frame = +1

Query: 136 LSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQEG 315
           L++G  IP IG+GTW+SKPGEV  A+K A+  GYRHI CA VY N+KEVGEA+K  + EG
Sbjct: 7   LNSGYSIPAIGLGTWQSKPGEVAAAIKTAVAAGYRHIDCAHVYQNQKEVGEALKEILDEG 66

Query: 316 VVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTD 495
            VKRE+LFITSK+WNTFH        +++ L +L + Y+DL LIHWPQ Y E   +FP  
Sbjct: 67  KVKREELFITSKVWNTFHSEAKAHENIDIILSDLQLSYVDLMLIHWPQGYAEGAELFPAG 126

Query: 496 ADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPGH*PGRMP 675
            +GK+++SDVDY++TWKA E     G  RS+G+SNF   Q+QR+ D A VKP      + 
Sbjct: 127 ENGKMRYSDVDYLETWKAFEAAQKAGKCRSIGLSNFTHSQIQRVWDAAEVKPACLQVELH 186

Query: 676 SVFKPXAIEAVLRRP*YYDNGVLPRWGXPDRPWAKPGDPHLMEDPKLKEIADRLGKXAAQ 855
             F    +    +       G  P        + K GDP+++ +  +  IA   GK  AQ
Sbjct: 187 PYFTQVKLREFCKEKGIVVVGYSPLGNPGSAFFRKDGDPNVLTNEVVAGIAKAHGKTPAQ 246


>UniRef50_UPI0000588153 Cluster: PREDICTED: hypothetical protein;
           n=1; Strongylocentrotus purpuratus|Rep: PREDICTED:
           hypothetical protein - Strongylocentrotus purpuratus
          Length = 333

 Score =  204 bits (497), Expect = 7e-51
 Identities = 103/243 (42%), Positives = 143/243 (58%), Gaps = 2/243 (0%)
 Frame = +1

Query: 133 TLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQE 312
           TL +G  +P++G+GTWK K  EV  A+  A+D GYRH  CA +YGNEKEVG A++  +Q 
Sbjct: 6   TLPSGHAMPLVGLGTWKLKADEVAGAIGAAVDAGYRHFDCALIYGNEKEVGVALREAMQR 65

Query: 313 GVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKE--DDAIF 486
             +KRED+FIT+K+WNTFH  + V      SL +L +DY+DLY++HWP  ++      +F
Sbjct: 66  LGLKREDVFITTKVWNTFHAKEDVAECFNRSLTDLQLDYIDLYIMHWPLGFQNLGPTVMF 125

Query: 487 PTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPGH*PG 666
           P    G I +SDV Y++TW A+E LV  G  +SLG+SNFNSKQL  +L +++V P     
Sbjct: 126 PRTETGDIVYSDVHYLETWSAMEDLVKTGKCKSLGLSNFNSKQLDDVLQHSTVPPSVLQV 185

Query: 667 RMPSVFKPXAIEAVLRRP*YYDNGVLPRWGXPDRPWAKPGDPHLMEDPKLKEIADRLGKX 846
                     +    R      +   P  G  DR W   G+P + +DP L +IA RL K 
Sbjct: 186 ESHPFLPQVELLNFCRERSVVVSAYSP-LGCGDRAWKLSGEPSIFDDPGLLKIAQRLRKS 244

Query: 847 AAQ 855
            AQ
Sbjct: 245 IAQ 247



 Score = 37.9 bits (84), Expect = 0.73
 Identities = 14/31 (45%), Positives = 20/31 (64%)
 Frame = +2

Query: 662 QVECHPYLNXKRLKQFCEDRDIMITXYSPXG 754
           QVE HP+L    L  FC +R ++++ YSP G
Sbjct: 184 QVESHPFLPQVELLNFCRERSVVVSAYSPLG 214


>UniRef50_Q7QK25 Cluster: ENSANGP00000019775; n=2; Anopheles gambiae
           str. PEST|Rep: ENSANGP00000019775 - Anopheles gambiae
           str. PEST
          Length = 319

 Score =  204 bits (497), Expect = 7e-51
 Identities = 112/252 (44%), Positives = 154/252 (61%), Gaps = 5/252 (1%)
 Frame = +1

Query: 115 TSVPVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAI 294
           T VP    SNG +IPV+G GT+ ++ G+  + VK AID+GYRHI  AF+Y NE E+G+AI
Sbjct: 3   TQVPTVRFSNGYEIPVLGYGTYLAQKGQCVELVKKAIDLGYRHIDTAFLYENEVEIGQAI 62

Query: 295 KTKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYK-- 468
           + KI EGV++RED+F+T+KLWNTFH P  V  A   S   L+I Y+DL+L+H P   +  
Sbjct: 63  RDKIAEGVIRREDVFVTTKLWNTFHDPQHVEEAFRRSFDMLDIGYIDLFLMHSPMGVQFS 122

Query: 469 --EDDAIFPTDADGKIQFSDVDYVDTWKALEPLV-CHGLVRSLGVSNFNSKQLQRILDNA 639
             E   + P DA G + FSDVDYV+TWKA+E LV   G VRS+G+SNFNS+Q++RIL  A
Sbjct: 123 GYEYADMQPKDAAGNMLFSDVDYVETWKAMEKLVTAGGRVRSIGLSNFNSEQIERILQIA 182

Query: 640 SVKPGH*PGRMPSVFKPXAIEAVLRRP*YYDNGVLPRWGXPDRPWAKPGDPHLMEDPKLK 819
           +VKP +        +    + A  +          P  G P R     G+ + ++DPK+ 
Sbjct: 183 TVKPVNNQVEANPGYDQRKLIAFCQARGITVTAYGP-MGRPHR--TTNGNRNALDDPKVL 239

Query: 820 EIADRLGKXAAQ 855
           EI  + GK   Q
Sbjct: 240 EIGRKYGKTGGQ 251



 Score = 36.3 bits (80), Expect = 2.2
 Identities = 15/34 (44%), Positives = 21/34 (61%)
 Frame = +2

Query: 653 VTNQVECHPYLNXKRLKQFCEDRDIMITXYSPXG 754
           V NQVE +P  + ++L  FC+ R I +T Y P G
Sbjct: 187 VNNQVEANPGYDQRKLIAFCQARGITVTAYGPMG 220


>UniRef50_Q0VGY1 Cluster: 3-alpha-hydroxysteroid dehydrogenase;
           n=13; Tetrapoda|Rep: 3-alpha-hydroxysteroid
           dehydrogenase - Xenopus tropicalis (Western clawed frog)
           (Silurana tropicalis)
          Length = 324

 Score =  202 bits (492), Expect = 3e-50
 Identities = 109/245 (44%), Positives = 142/245 (57%), Gaps = 5/245 (2%)
 Frame = +1

Query: 136 LSNGAKIPVIGIGTW---KSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKI 306
           L++G K+PVIG GT+   K       +  K AID+GYRHI CAF+YGNE+EVG AI+ KI
Sbjct: 11  LNDGHKMPVIGFGTYAPPKFPKSLAEEGTKVAIDVGYRHIDCAFLYGNEEEVGRAIRAKI 70

Query: 307 QEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIF 486
            +G VKRED+F T KLW+T H P+ VR ALE SL++L +DY+DL++IH P  +K  D +F
Sbjct: 71  ADGTVKREDVFYTGKLWSTSHTPERVRPALEKSLKDLQLDYMDLFIIHMPMEFKPGDDLF 130

Query: 487 PTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILD--NASVKPGH* 660
           P D +GK  + + D  DTWKALE     GLVRS+GVSNFN KQL+ IL+      KP   
Sbjct: 131 PADENGKFIYHNTDLRDTWKALEKCKDAGLVRSIGVSNFNHKQLELILNMPGLKYKPVCN 190

Query: 661 PGRMPSVFKPXAIEAVLRRP*YYDNGVLPRWGXPDRPWAKPGDPHLMEDPKLKEIADRLG 840
                       +    +       G        D  W +   P L+EDP L EIA +  
Sbjct: 191 QVECHVYLNQSKLLEFCKSKDIVLVGYSVLGSSRDERWIEASTPVLLEDPALTEIAKKHN 250

Query: 841 KXAAQ 855
           +  AQ
Sbjct: 251 RTPAQ 255



 Score = 46.0 bits (104), Expect = 0.003
 Identities = 18/34 (52%), Positives = 24/34 (70%)
 Frame = +2

Query: 653 VTNQVECHPYLNXKRLKQFCEDRDIMITXYSPXG 754
           V NQVECH YLN  +L +FC+ +DI++  YS  G
Sbjct: 188 VCNQVECHVYLNQSKLLEFCKSKDIVLVGYSVLG 221


>UniRef50_Q17DN0 Cluster: Aldo-keto reductase; n=5; Culicidae|Rep:
           Aldo-keto reductase - Aedes aegypti (Yellowfever
           mosquito)
          Length = 324

 Score =  195 bits (475), Expect = 3e-48
 Identities = 97/181 (53%), Positives = 124/181 (68%), Gaps = 4/181 (2%)
 Frame = +1

Query: 121 VPVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKT 300
           +P   L+NG ++P IG+GT  SK  E  +AV  AID G+RHI  A+ Y NE  VG AI+ 
Sbjct: 6   IPTVKLNNGLEMPAIGLGTSMSKGDECCKAVMTAIDEGFRHIDTAYNYRNEDVVGRAIRA 65

Query: 301 KIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYK---- 468
           KI+EGVV RE+LF+T+KLWNTFH PD V  A   SL +L +DY+DL+LIH P  Y+    
Sbjct: 66  KIEEGVVTREELFVTTKLWNTFHHPDHVPMAFGKSLEHLGLDYVDLFLIHMPFGYEFNGW 125

Query: 469 EDDAIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVK 648
           + +   P D +G +  SD DYVDTWKA+E L+  G V S+GVSNFNS+QL+RIL N  VK
Sbjct: 126 DPEKRTPLDDNGNVLCSDDDYVDTWKAMEKLLESGRVHSIGVSNFNSEQLERILANCRVK 185

Query: 649 P 651
           P
Sbjct: 186 P 186



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 19/34 (55%), Positives = 25/34 (73%)
 Frame = +2

Query: 653 VTNQVECHPYLNXKRLKQFCEDRDIMITXYSPXG 754
           VTNQVEC   +N K L +FC +RDI++T +SP G
Sbjct: 187 VTNQVECSARINQKLLIEFCMERDIVVTAHSPFG 220


>UniRef50_UPI00015B56A3 Cluster: PREDICTED: similar to aldo-keto
           reductase; n=1; Nasonia vitripennis|Rep: PREDICTED:
           similar to aldo-keto reductase - Nasonia vitripennis
          Length = 321

 Score =  192 bits (469), Expect = 2e-47
 Identities = 88/175 (50%), Positives = 122/175 (69%), Gaps = 2/175 (1%)
 Frame = +1

Query: 133 TLSNGAKIPVIGIGTWK--SKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKI 306
           TLS+G K+PV+G+GTW+  + P EV  AVK AID GYRH  CA  YGNE E+G+AI+ KI
Sbjct: 9   TLSDGNKVPVLGLGTWQGGNDPDEVENAVKLAIDAGYRHFDCASFYGNEAEIGKAIQEKI 68

Query: 307 QEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIF 486
            +GVVKREDLF+ +K+WN   + +LV  A + SL+ L + Y+DLYL+HWP +Y       
Sbjct: 69  DQGVVKREDLFVVTKVWNDERKQELVVAACKRSLKKLGLGYIDLYLVHWPFSYPILYQYI 128

Query: 487 PTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKP 651
                  +   +VDY++TW+ +E  +  GL RS+GVSNFNS+QL R+L++AS+KP
Sbjct: 129 VLPTYNAVTLDEVDYIETWRGMEECIKLGLTRSIGVSNFNSQQLTRLLESASIKP 183



 Score = 43.2 bits (97), Expect = 0.019
 Identities = 17/34 (50%), Positives = 23/34 (67%)
 Frame = +2

Query: 653 VTNQVECHPYLNXKRLKQFCEDRDIMITXYSPXG 754
           V NQ+E H  LN K+L++FC  + I +T YSP G
Sbjct: 184 VMNQIELHINLNQKKLREFCASKSIAVTGYSPFG 217


>UniRef50_Q2S340 Cluster: Aldehyde reductase; n=10; Bacteria|Rep:
           Aldehyde reductase - Salinibacter ruber (strain DSM
           13855)
          Length = 321

 Score =  190 bits (463), Expect = 9e-47
 Identities = 104/243 (42%), Positives = 137/243 (56%), Gaps = 2/243 (0%)
 Frame = +1

Query: 133 TLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQE 312
           +  NG ++P+IG+GTWKS PGEV +AV  A++ GYRH+ CA +Y NE EVG A+      
Sbjct: 5   SFENGDEMPMIGLGTWKSPPGEVYEAVTTALEAGYRHVDCAPIYKNETEVGAALSDSFDA 64

Query: 313 GVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPT 492
           G ++R+D+++TSKLWN  H PD VR ALE +L +L +D LDLYLIHWP A  + +  FP 
Sbjct: 65  GGIRRDDVWVTSKLWNNAHHPDDVRPALEQTLSDLRLDALDLYLIHWPVAL-QPEVDFPE 123

Query: 493 DADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPGH*PGRM 672
             D  +    V   +TW A+E L   GLVR +GVSNF+   LQ ILD   V+P      M
Sbjct: 124 SPDDFVSPEAVPLTETWAAMEALKKDGLVRHIGVSNFSVPNLQMILDAGEVRPEMNQVEM 183

Query: 673 PSVFKPXAIEAVLRRP*YYDNGVLPRWGXPDRPWAKPGD--PHLMEDPKLKEIADRLGKX 846
                   + +             P  G  DRP A   D  P LM +P + +IADR G  
Sbjct: 184 HPYLPQPELVSFAEAHNIPITAYSP-LGSGDRPDAMKADDEPTLMANPTINDIADRHGVS 242

Query: 847 AAQ 855
            AQ
Sbjct: 243 PAQ 245



 Score = 38.7 bits (86), Expect = 0.42
 Identities = 18/32 (56%), Positives = 19/32 (59%)
 Frame = +2

Query: 659 NQVECHPYLNXKRLKQFCEDRDIMITXYSPXG 754
           NQVE HPYL    L  F E  +I IT YSP G
Sbjct: 179 NQVEMHPYLPQPELVSFAEAHNIPITAYSPLG 210


>UniRef50_A5KSS3 Cluster: Aldehyde reductase; n=1; candidate
           division TM7 genomosp. GTL1|Rep: Aldehyde reductase -
           candidate division TM7 genomosp. GTL1
          Length = 299

 Score =  190 bits (462), Expect = 1e-46
 Identities = 103/241 (42%), Positives = 138/241 (57%)
 Frame = +1

Query: 133 TLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQE 312
           TL N   +P++G GTW+   G     V+ AI  GYRHI CA +YGNEKEVGE I+  I +
Sbjct: 5   TLRNKQTLPLLGYGTWELPTGTTADLVETAIKAGYRHIDCAMIYGNEKEVGEGIRRTIDQ 64

Query: 313 GVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPT 492
           GVVKREDLF+TSKLWNT H    V  A   +L +L +DYLDLYLIHW  A++  D + P 
Sbjct: 65  GVVKREDLFVTSKLWNTDHAQVDVGVACRKTLNDLGLDYLDLYLIHWGVAFEHGDNLEPL 124

Query: 493 DADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPGH*PGRM 672
           D DG  +FS +   +TW+A+E LV  GLV+S+GV+NF +  L  +L  A +KP      +
Sbjct: 125 DDDGVAKFSFISMKETWQAMEELVEQGLVKSMGVANFTAPMLLDLLSYAKIKPAVHQIEL 184

Query: 673 PSVFKPXAIEAVLRRP*YYDNGVLPRWGXPDRPWAKPGDPHLMEDPKLKEIADRLGKXAA 852
                   + A      Y  N  +  +     P+     P ++ DP +KE+A  LGK  A
Sbjct: 185 HPYLAQNDLVAFC----YSQNIAVTAYS----PFGSTEAP-VLTDPTVKEVAKGLGKTPA 235

Query: 853 Q 855
           Q
Sbjct: 236 Q 236



 Score = 37.5 bits (83), Expect = 0.97
 Identities = 15/32 (46%), Positives = 20/32 (62%)
 Frame = +2

Query: 659 NQVECHPYLNXKRLKQFCEDRDIMITXYSPXG 754
           +Q+E HPYL    L  FC  ++I +T YSP G
Sbjct: 180 HQIELHPYLAQNDLVAFCYSQNIAVTAYSPFG 211


>UniRef50_Q8K023 Cluster: Aldo-keto reductase family 1 member C18;
           n=72; Tetrapoda|Rep: Aldo-keto reductase family 1 member
           C18 - Mus musculus (Mouse)
          Length = 323

 Score =  185 bits (451), Expect = 2e-45
 Identities = 86/174 (49%), Positives = 124/174 (71%), Gaps = 3/174 (1%)
 Frame = +1

Query: 136 LSNGAKIPVIGIGTWKSKPG---EVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKI 306
           L++G  IPV+G GT+ ++     +  ++ K AID+G+ HI C+ +Y NE+E+G+AI +KI
Sbjct: 10  LNDGHSIPVLGFGTYATEEHLKKKSMESTKIAIDVGFCHIDCSHLYQNEEEIGQAILSKI 69

Query: 307 QEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIF 486
           ++G VKRED+F TSKLW+T HRP+LVR +LE SLR LN+DY+DLYLIH+P + K  + + 
Sbjct: 70  EDGTVKREDIFYTSKLWSTSHRPELVRPSLENSLRKLNLDYVDLYLIHFPVSLKPGNELL 129

Query: 487 PTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVK 648
           P D  G + F  VD  DTW+A+E     GL +S+GVSNFN +QL+ IL+   +K
Sbjct: 130 PKDEHGNLIFDTVDLCDTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLK 183



 Score = 39.9 bits (89), Expect = 0.18
 Identities = 16/34 (47%), Positives = 21/34 (61%)
 Frame = +2

Query: 653 VTNQVECHPYLNXKRLKQFCEDRDIMITXYSPXG 754
           V NQVECH YLN  +L  +C+  DI++  Y   G
Sbjct: 187 VCNQVECHLYLNQSKLLAYCKMNDIVLVAYGALG 220


>UniRef50_A2QBD7 Cluster: Catalytic activity: an alcohol + NADP(+)
           <=> an aldehyde + NADPH; n=4; Trichocomaceae|Rep:
           Catalytic activity: an alcohol + NADP(+) <=> an aldehyde
           + NADPH - Aspergillus niger
          Length = 323

 Score =  184 bits (447), Expect = 8e-45
 Identities = 85/173 (49%), Positives = 120/173 (69%)
 Frame = +1

Query: 133 TLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQE 312
           T++ GAKIP +G GTW++KP EV  AV+ A+  GYRHI CA +Y NE EVG  I+    +
Sbjct: 8   TINTGAKIPAVGFGTWQAKPLEVENAVEVALREGYRHIDCAAIYRNETEVGNGIR----K 63

Query: 313 GVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPT 492
             V RE++FIT KLWNT H P+ V  AL+ +L++L + YLDLYL+HWP A+K  D  FP 
Sbjct: 64  SGVPREEIFITGKLWNTKHAPEDVEPALDKTLQDLGVAYLDLYLMHWPCAFKGGDKWFPL 123

Query: 493 DADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKP 651
           + DG    +++DY+ T++A+E L+  G VR++GVSNFN ++L+ +L   SV P
Sbjct: 124 NDDGVFDLANIDYITTYRAMEKLLATGKVRAIGVSNFNIRRLEELLGQVSVVP 176



 Score = 43.2 bits (97), Expect = 0.019
 Identities = 17/32 (53%), Positives = 21/32 (65%)
 Frame = +2

Query: 659 NQVECHPYLNXKRLKQFCEDRDIMITXYSPXG 754
           NQ+E HPYL    L QFC+ + I+I  YSP G
Sbjct: 179 NQIEAHPYLQQPDLLQFCQSKGILIEAYSPLG 210


>UniRef50_UPI000065D0BD Cluster: Homolog of Homo sapiens "AKR1B1
           protein.; n=1; Takifugu rubripes|Rep: Homolog of Homo
           sapiens "AKR1B1 protein. - Takifugu rubripes
          Length = 330

 Score =  183 bits (446), Expect = 1e-44
 Identities = 107/272 (39%), Positives = 146/272 (53%), Gaps = 27/272 (9%)
 Frame = +1

Query: 121 VPVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKT 300
           +P  TL+ GA +PV+G+GTWKS  G  T+AVK AI  GYRHI  A+VY NE EVG  ++ 
Sbjct: 2   IPSVTLNTGALMPVLGLGTWKSGKGVTTEAVKVAIGAGYRHIDTAYVYENETEVGAGVQA 61

Query: 301 KIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKE--- 471
            I +GVVKRE+LFI SKLW TFH P LVRGA E +L +LN+DY+DLYL+H+P        
Sbjct: 62  MIDQGVVKREELFIVSKLWCTFHTPSLVRGACEKTLSSLNLDYVDLYLMHFPMGALSATL 121

Query: 472 -----DDAI----------------FPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSL 588
                 D I                FP D   ++      ++DTW+A+E LV  GL +++
Sbjct: 122 DLTSLTDVIPTVFRDFSPLQPGEDPFPLDEHNQLICDGTSFLDTWEAMEELVDDGLAKAI 181

Query: 589 GVSNFNSKQLQRILDNASVKPGH*PGRMPSVFKPXAIEAVL---RRP*YYDNGVLPRWGX 759
           G+SNFN  Q++ +L+   +K  H P        P   +  L    R            G 
Sbjct: 182 GISNFNKDQIEAVLNKPGLK--HKPATNQIECHPHLNQEKLIHFCRSRGISVTAFACLGS 239

Query: 760 PDRPWAKPGDPHLMEDPKLKEIADRLGKXAAQ 855
            DR WA   +P  ++DP++  IA +     AQ
Sbjct: 240 ADRSWASADEPSFLDDPQINAIARKNQMTPAQ 271



 Score = 43.6 bits (98), Expect = 0.015
 Identities = 16/33 (48%), Positives = 23/33 (69%)
 Frame = +2

Query: 656 TNQVECHPYLNXKRLKQFCEDRDIMITXYSPXG 754
           TNQ+ECHP+LN ++L  FC  R I +T ++  G
Sbjct: 206 TNQIECHPHLNQEKLIHFCRSRGISVTAFACLG 238


>UniRef50_A7SIT3 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 323

 Score =  183 bits (445), Expect = 1e-44
 Identities = 98/234 (41%), Positives = 141/234 (60%), Gaps = 3/234 (1%)
 Frame = +1

Query: 136 LSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQEG 315
           L+ GA IP + +GTW+S   EV  AV+ AI++GYRHI CA +YGNE E+GEA+   + EG
Sbjct: 10  LNTGASIPAMALGTWQSSKEEVGNAVRLAIELGYRHIDCAEIYGNEGEIGEALSEVLTEG 69

Query: 316 VVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTD 495
            VKRE+LF+TSKLW   H PD V  A + +L+NL +DYLDLYLIH P A+K+   +  + 
Sbjct: 70  KVKREELFVTSKLWCDSHHPDDVLPACQATLKNLQLDYLDLYLIHIPVAFKKGVRLPHSI 129

Query: 496 ADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPGH*PGRMP 675
           A+G I ++     +TW+A+E LV  GL +++GVSNF+ K+L ++L+ AS+ P      + 
Sbjct: 130 AEGIIGYTPEGVQNTWQAMEGLVAKGLCKAIGVSNFSVKRLNKLLETASIVPACNQVELH 189

Query: 676 SVFKPXAIEAVLRRP*YYDNGVLPRWGXPDRPWAK---PGDPHLMEDPKLKEIA 828
                  ++              P  G P R   K     +P +ME+P +KEIA
Sbjct: 190 PYLPQEKLKEFCDSKGILLTAYSP-LGNPGRLVPKERLEREPKVMEEPVIKEIA 242



 Score = 48.0 bits (109), Expect = 7e-04
 Identities = 18/32 (56%), Positives = 25/32 (78%)
 Frame = +2

Query: 659 NQVECHPYLNXKRLKQFCEDRDIMITXYSPXG 754
           NQVE HPYL  ++LK+FC+ + I++T YSP G
Sbjct: 184 NQVELHPYLPQEKLKEFCDSKGILLTAYSPLG 215


>UniRef50_Q10494 Cluster: Probable oxidoreductase C26F1.07; n=2;
           Schizosaccharomyces pombe|Rep: Probable oxidoreductase
           C26F1.07 - Schizosaccharomyces pombe (Fission yeast)
          Length = 321

 Score =  182 bits (443), Expect = 2e-44
 Identities = 86/173 (49%), Positives = 117/173 (67%)
 Frame = +1

Query: 133 TLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQE 312
           TL++G+KIP +G+GTW+S+P +   AVK A+  GYRHI  A +YGNE EVG+ IK    E
Sbjct: 17  TLADGSKIPGLGLGTWRSEPNQTKNAVKTALQYGYRHIDAAAIYGNEDEVGDGIK----E 72

Query: 313 GVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPT 492
             V R+D+++TSKLW   H P+ V  ALE +L++L +DYLD YLIHWP ++K  +  FP 
Sbjct: 73  SGVPRKDIWVTSKLWCNAHAPEAVPKALEKTLKDLKLDYLDEYLIHWPVSFKTGEDKFPK 132

Query: 493 DADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKP 651
           D DG + +      +TWKA+E L+  G VR +G+SNFN   L+RIL  A VKP
Sbjct: 133 DKDGNLIYEKNPIEETWKAMEKLLETGKVRHIGLSNFNDTNLERILKVAKVKP 185


>UniRef50_P51857 Cluster: 3-oxo-5-beta-steroid 4-dehydrogenase (EC
           1.3.1.3) (Delta(4)-3- ketosteroid 5-beta-reductase);
           n=124; cellular organisms|Rep: 3-oxo-5-beta-steroid
           4-dehydrogenase (EC 1.3.1.3) (Delta(4)-3- ketosteroid
           5-beta-reductase) - Homo sapiens (Human)
          Length = 326

 Score =  182 bits (442), Expect = 3e-44
 Identities = 107/248 (43%), Positives = 143/248 (57%), Gaps = 8/248 (3%)
 Frame = +1

Query: 136 LSNGAKIPVIGIGTW---KSKP-GEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTK 303
           LS+G  IP+IG+GT+   KS P G    +VK AID GYRHI  A++Y NE EVGEAI+ K
Sbjct: 12  LSDGNSIPIIGLGTYSEPKSTPKGACATSVKVAIDTGYRHIDGAYIYQNEHEVGEAIREK 71

Query: 304 IQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAI 483
           I EG V+RED+F   KLW T H P++VR  LE +LR L +DY+DLY+I  P A+K  D I
Sbjct: 72  IAEGKVRREDIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLYIIEVPMAFKPGDEI 131

Query: 484 FPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPGH*P 663
           +P D +GK  +   +   TW+A+E     GLV+SLGVSNFN +QL+ IL+   +K  H P
Sbjct: 132 YPRDENGKWLYHKSNLCATWEAMEACKDAGLVKSLGVSNFNRRQLELILNKPGLK--HKP 189

Query: 664 GRMPSVFKPXAIEAVLRRP*YYDNGVLPRW---GXPDRP-WAKPGDPHLMEDPKLKEIAD 831
                   P   +  L +     + V+  +   G    P W     P L++D  L  +  
Sbjct: 190 VSNQVECHPYFTQPKLLKFCQQHDIVITAYSPLGTSRNPIWVNVSSPPLLKDALLNSLGK 249

Query: 832 RLGKXAAQ 855
           R  K AAQ
Sbjct: 250 RYNKTAAQ 257


>UniRef50_Q7JVH6 Cluster: LD24696p; n=2; Sophophora|Rep: LD24696p -
           Drosophila melanogaster (Fruit fly)
          Length = 311

 Score =  181 bits (441), Expect = 4e-44
 Identities = 84/181 (46%), Positives = 123/181 (67%), Gaps = 1/181 (0%)
 Frame = +1

Query: 112 MTSV-PVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGE 288
           MT++ P   L+NG ++P +G+GTWKS   +   + + A+D+GYRH+  AFVY NE EVG+
Sbjct: 1   MTNLAPTIRLNNGREMPTLGLGTWKSFESDAYHSTRHALDVGYRHLDTAFVYENEAEVGQ 60

Query: 289 AIKTKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYK 468
           AI  KI EGVV RE++F+T+KL    H P LV  A  +SL NL ++Y+DLYL+H P   K
Sbjct: 61  AISEKIAEGVVTREEVFVTTKLGGIHHDPALVERACRLSLSNLGLEYVDLYLMHMPVGQK 120

Query: 469 EDDAIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVK 648
             +    ++  G ++ +DVDY+DTW+ +E LV  GL RS+G+SNFN+ Q +R+L N  ++
Sbjct: 121 FHN---DSNVHGTLELTDVDYLDTWREMEKLVDLGLTRSIGLSNFNAAQTERVLANCRIR 177

Query: 649 P 651
           P
Sbjct: 178 P 178


>UniRef50_UPI0000E4A7CE Cluster: PREDICTED: similar to LOC553452
           protein; n=6; Strongylocentrotus purpuratus|Rep:
           PREDICTED: similar to LOC553452 protein -
           Strongylocentrotus purpuratus
          Length = 321

 Score =  180 bits (437), Expect = 1e-43
 Identities = 104/244 (42%), Positives = 136/244 (55%), Gaps = 4/244 (1%)
 Frame = +1

Query: 136 LSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQEG 315
           L  G K+P++G GTW+ KP EV + ++ AID GYRHI  A +YGNEK VG+ IK KI +G
Sbjct: 10  LPGGRKLPLLGFGTWQIKPEEVGRVIETAIDCGYRHIDEASLYGNEKGVGDGIKAKIDDG 69

Query: 316 VVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTD 495
            +KREDLF+TSKLW T   P  V  +   SL +L + YLDL+LIH P +       FP D
Sbjct: 70  TIKREDLFVTSKLWVTDSHPSRVEPSCRQSLSDLGLAYLDLFLIHCPTSAVGGKGPFPMD 129

Query: 496 ADGKIQFSD-VDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKP-GH*PGR 669
            +G     D +DYVDTW+ +E LV  GLVR++GVSNF   Q+QR+LD     P  +    
Sbjct: 130 DNGLFIGDDTIDYVDTWRIMESLVDKGLVRAIGVSNFTVAQIQRVLDLPPKYPIANVQVE 189

Query: 670 MPSVFKPXAIEAVLRRP*YYDNGVLPRWGXPDRPWAKPG--DPHLMEDPKLKEIADRLGK 843
                    +    ++         P  G P+R   K    DP LMEDP +  IA + G 
Sbjct: 190 CHPFLAQNELIEFCKKQGITVTAYSP-LGSPERVLQKRATTDPLLMEDPVVCAIAKKKGV 248

Query: 844 XAAQ 855
             AQ
Sbjct: 249 SPAQ 252



 Score = 41.5 bits (93), Expect = 0.060
 Identities = 16/31 (51%), Positives = 21/31 (67%)
 Frame = +2

Query: 662 QVECHPYLNXKRLKQFCEDRDIMITXYSPXG 754
           QVECHP+L    L +FC+ + I +T YSP G
Sbjct: 187 QVECHPFLAQNELIEFCKKQGITVTAYSPLG 217


>UniRef50_Q96JD6-2 Cluster: Isoform 2 of Q96JD6 ; n=4;
           Catarrhini|Rep: Isoform 2 of Q96JD6 - Homo sapiens
           (Human)
          Length = 263

 Score =  180 bits (437), Expect = 1e-43
 Identities = 87/184 (47%), Positives = 120/184 (65%), Gaps = 19/184 (10%)
 Frame = +1

Query: 154 IPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQEGVVKRED 333
           IP +G+ +WK+ PG+VT+AVK+AID GYRH  CA+ Y NE+EVG  I+ KI+EG V+RED
Sbjct: 4   IPAVGLSSWKASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEGAVRRED 63

Query: 334 LFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKE---------DDAIF 486
           LFI +KLW T H+  LV  A   SL+ L ++YLDLYLIHWP  +K           +  F
Sbjct: 64  LFIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPMGFKPPHPEWIMSCSELSF 123

Query: 487 ----------PTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDN 636
                     P D    +  SD D++DTW+A+E LV  GLV+++GVSNFN +QL+R+L+ 
Sbjct: 124 CLSHPRVQDLPLDESNMVIPSDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERLLNK 183

Query: 637 ASVK 648
             ++
Sbjct: 184 PGLR 187


>UniRef50_Q96JD6 Cluster: Aldo-keto reductase family 1 member C-like
           protein 2; n=37; Euteleostomi|Rep: Aldo-keto reductase
           family 1 member C-like protein 2 - Homo sapiens (Human)
          Length = 320

 Score =  180 bits (437), Expect = 1e-43
 Identities = 87/184 (47%), Positives = 120/184 (65%), Gaps = 19/184 (10%)
 Frame = +1

Query: 154 IPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQEGVVKRED 333
           IP +G+ +WK+ PG+VT+AVK+AID GYRH  CA+ Y NE+EVG  I+ KI+EG V+RED
Sbjct: 4   IPAVGLSSWKASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEGAVRRED 63

Query: 334 LFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKE---------DDAIF 486
           LFI +KLW T H+  LV  A   SL+ L ++YLDLYLIHWP  +K           +  F
Sbjct: 64  LFIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPMGFKPPHPEWIMSCSELSF 123

Query: 487 ----------PTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDN 636
                     P D    +  SD D++DTW+A+E LV  GLV+++GVSNFN +QL+R+L+ 
Sbjct: 124 CLSHPRVQDLPLDESNMVIPSDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERLLNK 183

Query: 637 ASVK 648
             ++
Sbjct: 184 PGLR 187



 Score = 52.4 bits (120), Expect = 3e-05
 Identities = 19/34 (55%), Positives = 24/34 (70%)
 Frame = +2

Query: 653 VTNQVECHPYLNXKRLKQFCEDRDIMITXYSPXG 754
           +TNQ+ECHPYL  K L  FC+ RD+ +T Y P G
Sbjct: 191 LTNQIECHPYLTQKNLISFCQSRDVSVTAYRPLG 224


>UniRef50_Q0PGJ6 Cluster: Aldo-keto reductase; n=32;
           Magnoliophyta|Rep: Aldo-keto reductase - Arabidopsis
           thaliana (Mouse-ear cress)
          Length = 315

 Score =  179 bits (435), Expect = 2e-43
 Identities = 97/240 (40%), Positives = 138/240 (57%)
 Frame = +1

Query: 136 LSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQEG 315
           L+ GAK P +G+GTW++ PG V  AV  A+ IGYRHI CA +YGNEKE+G  +K   ++ 
Sbjct: 10  LNTGAKFPSVGLGTWQASPGLVGDAVAAAVKIGYRHIDCAQIYGNEKEIGAVLKKLFEDR 69

Query: 316 VVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTD 495
           VVKREDLFITSKLW T H P  V  AL  +L++L ++Y+DLYLIHWP   K+       +
Sbjct: 70  VVKREDLFITSKLWCTDHDPQDVPEALNRTLKDLQLEYVDLYLIHWPARIKKGSVGIKPE 129

Query: 496 ADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPGH*PGRMP 675
                    VD   TWKA+E L   G  R++GVSNF++K+L  +L+ A V P        
Sbjct: 130 -----NLLPVDIPSTWKAMEALYDSGKARAIGVSNFSTKKLADLLELARVPPAVNQVECH 184

Query: 676 SVFKPXAIEAVLRRP*YYDNGVLPRWGXPDRPWAKPGDPHLMEDPKLKEIADRLGKXAAQ 855
             ++   ++   +    + +   P  G P   W K     ++++P L  +A++LGK  AQ
Sbjct: 185 PSWRQTKLQEFCKSKGVHLSAYSP-LGSPGTTWLK---SDVLKNPILNMVAEKLGKSPAQ 240


>UniRef50_P27800 Cluster: Aldehyde reductase 1; n=18; root|Rep:
           Aldehyde reductase 1 - Sporobolomyces salmonicolor
          Length = 323

 Score =  179 bits (435), Expect = 2e-43
 Identities = 107/251 (42%), Positives = 149/251 (59%), Gaps = 6/251 (2%)
 Frame = +1

Query: 121 VPVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKT 300
           V  TTL+ GA + ++G GTW++ PGEV Q VK AI+ GYRH+  A VY N+ EVG AIK 
Sbjct: 2   VGTTTLNTGASLELVGYGTWQAAPGEVGQGVKVAIETGYRHLDLAKVYSNQPEVGAAIK- 60

Query: 301 KIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAY-KEDD 477
              E  VKREDLFITSKLWN  HRP+ V  AL+ +L+ L ++YLDLYLIHWP A+  E D
Sbjct: 61  ---EAGVKREDLFITSKLWNNSHRPEQVEPALDDTLKELGLEYLDLYLIHWPVAFPPEGD 117

Query: 478 A---IFPTDADGKIQFS-DVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASV 645
               +FP   D +++   +V  VDTWKA+  L+  G V+++GVSNF++K +  I++   V
Sbjct: 118 ITQNLFPKANDKEVKLDLEVSLVDTWKAMVKLLDTGKVKAIGVSNFDAKMVDAIIEATGV 177

Query: 646 KPG-H*PGRMPSVFKPXAIEAVLRRP*YYDNGVLPRWGXPDRPWAKPGDPHLMEDPKLKE 822
            P  +   R P + +P  I A  +    +     P            G P L++ P++K 
Sbjct: 178 TPSVNQIERHPLLLQPELI-AHHKAKNIHITAYSPLGNN------TVGAPLLVQHPEIKR 230

Query: 823 IADRLGKXAAQ 855
           IA++ G   AQ
Sbjct: 231 IAEKNGCTPAQ 241


>UniRef50_Q8VC28 Cluster: Aldo-keto reductase family 1 member C13;
           n=11; Theria|Rep: Aldo-keto reductase family 1 member
           C13 - Mus musculus (Mouse)
          Length = 323

 Score =  179 bits (435), Expect = 2e-43
 Identities = 85/174 (48%), Positives = 122/174 (70%), Gaps = 3/174 (1%)
 Frame = +1

Query: 136 LSNGAKIPVIGIGTWKSKPGEVTQAVKDA---IDIGYRHIXCAFVYGNEKEVGEAIKTKI 306
           L++G  IP +G GT+K K    +++++ A   +D+GYRH+  A+ Y  E+E+G+AI++KI
Sbjct: 10  LNDGHLIPALGFGTYKPKEVPKSKSLEAACLALDVGYRHVDTAYAYQVEEEIGQAIQSKI 69

Query: 307 QEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIF 486
           + GVVKREDLFIT+KLW T  RP+LV+ ALE SL+ L +DY+DLY++H+P   K  D  F
Sbjct: 70  KAGVVKREDLFITTKLWCTCFRPELVKPALEKSLKKLQLDYVDLYIMHYPVPMKSGDNDF 129

Query: 487 PTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVK 648
           P +  GK     VD+ DTW+ LE     GLV+S+GVSNFN +QL+RIL+   +K
Sbjct: 130 PVNEQGKSLLDTVDFCDTWERLEECKDAGLVKSIGVSNFNHRQLERILNKPGLK 183



 Score = 44.8 bits (101), Expect = 0.006
 Identities = 17/34 (50%), Positives = 23/34 (67%)
 Frame = +2

Query: 653 VTNQVECHPYLNXKRLKQFCEDRDIMITXYSPXG 754
           V NQVECH YLN ++L  +CE +DI++  Y   G
Sbjct: 187 VCNQVECHLYLNQRKLLDYCESKDIVLVAYGALG 220


>UniRef50_Q54B70 Cluster: Aldehyde reductase; n=2; Dictyostelium
           discoideum|Rep: Aldehyde reductase - Dictyostelium
           discoideum AX4
          Length = 297

 Score =  178 bits (433), Expect = 4e-43
 Identities = 92/177 (51%), Positives = 118/177 (66%), Gaps = 1/177 (0%)
 Frame = +1

Query: 124 PVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTK 303
           P   LS+G KIP++G GTWK++   V +AV+ A+D GYRHI CA VY NEKEVGEA   K
Sbjct: 3   PSFKLSSGHKIPLVGFGTWKAETTLVGKAVEVALDAGYRHIDCAAVYLNEKEVGEAFTKK 62

Query: 304 IQ-EGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDA 480
              E  VKRED+FITSKLWNTFH+ + VR ALE +L +L + YLDLYL+HWP A++    
Sbjct: 63  FTTEATVKREDVFITSKLWNTFHKKEHVRPALERTLSDLGLQYLDLYLVHWPVAFEYTSN 122

Query: 481 IFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKP 651
              T   G  Q   V   +TW+ +E LV  GLV+S+G+SNFN + L  +L  A +KP
Sbjct: 123 DIQT--SGSTQ-EFVSIRETWEEMEKLVDAGLVKSIGLSNFNVQGLMEVLSYARIKP 176



 Score = 43.6 bits (98), Expect = 0.015
 Identities = 17/32 (53%), Positives = 23/32 (71%)
 Frame = +2

Query: 659 NQVECHPYLNXKRLKQFCEDRDIMITXYSPXG 754
           NQVE HP+L+   LK+FC+  +I +T YSP G
Sbjct: 179 NQVELHPFLSQPELKKFCDKHNIHLTAYSPLG 210


>UniRef50_UPI0000E45E29 Cluster: PREDICTED: similar to aldose
           reductase; n=1; Strongylocentrotus purpuratus|Rep:
           PREDICTED: similar to aldose reductase -
           Strongylocentrotus purpuratus
          Length = 274

 Score =  177 bits (430), Expect = 9e-43
 Identities = 95/226 (42%), Positives = 127/226 (56%)
 Frame = +1

Query: 178 WKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQEGVVKREDLFITSKLW 357
           W SKPG+V  AVK AID GYRHI CA VYGNE EVG  +K K    VVKRED+FITSKLW
Sbjct: 5   WMSKPGQVEAAVKAAIDCGYRHIDCAHVYGNEAEVGAGLKEKFDANVVKREDIFITSKLW 64

Query: 358 NTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTDADGKIQFSDVDYVD 537
           N  H PD V  A +++L+NL + Y+DLYL+HWP AY                        
Sbjct: 65  NNKHHPDDVEQACDITLKNLQLSYVDLYLMHWPMAY------------------------ 100

Query: 538 TWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPGH*PGRMPSVFKPXAIEAVLRR 717
             +A+E LV  G  +++G+SNF+ K ++R+++ A+++P +    +  +     +    + 
Sbjct: 101 --QAMEKLVTSGKCKAIGLSNFSMKMMKRVIEKATIQPANLQVELHPLLTQEKLIEFCKE 158

Query: 718 P*YYDNGVLPRWGXPDRPWAKPGDPHLMEDPKLKEIADRLGKXAAQ 855
                    P  G PDRPW K  DP LMEDP +  IA + GK  AQ
Sbjct: 159 HNMTVTAYSP-LGAPDRPWVKDDDPKLMEDPIVTGIATKKGKSPAQ 203


>UniRef50_Q5BKE9 Cluster: LOC594893 protein; n=5; Xenopus
           tropicalis|Rep: LOC594893 protein - Xenopus tropicalis
           (Western clawed frog) (Silurana tropicalis)
          Length = 345

 Score =  175 bits (425), Expect = 4e-42
 Identities = 98/232 (42%), Positives = 133/232 (57%), Gaps = 4/232 (1%)
 Frame = +1

Query: 172 GTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQEGVVKREDLFITSK 351
           GT KS   +V  A K A+D+GYRH+  AF+Y +E  VG+A + K  +G +KREDLF TSK
Sbjct: 47  GTEKSFIDDVRVATKMALDLGYRHVDGAFLYSSETGVGQAFREKFADGTLKREDLFYTSK 106

Query: 352 LWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTDADGKIQFSDVDY 531
           LWNTFH+P LVR ALE +L  L +DY+DLYLIH P ++K  + +FP + DG   F   D 
Sbjct: 107 LWNTFHQPHLVRPALEKTLSFLQMDYVDLYLIHMPMSFKPAEELFPKNEDGTCAFDQPDL 166

Query: 532 VDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPGH*PGRMPSVFKPXAIEAVL 711
           + TW+ALE     GLV+S+GVSNFN +QL+ IL+   +K  + P        P   +  +
Sbjct: 167 LQTWQALEECRDAGLVKSIGVSNFNRRQLEMILNKPGLK--YKPVCNQIECHPYLNQKQM 224

Query: 712 RRP*YYDNGVLPRWGXPDRP----WAKPGDPHLMEDPKLKEIADRLGKXAAQ 855
                  + V+  +G    P    W     P L+EDP L  I  +  K  AQ
Sbjct: 225 LEFCKSKDIVVVAYGVLGSPGAGKWVDQSCPILLEDPVLISIGQKYSKSPAQ 276



 Score = 48.8 bits (111), Expect = 4e-04
 Identities = 17/34 (50%), Positives = 25/34 (73%)
 Frame = +2

Query: 653 VTNQVECHPYLNXKRLKQFCEDRDIMITXYSPXG 754
           V NQ+ECHPYLN K++ +FC+ +DI++  Y   G
Sbjct: 209 VCNQIECHPYLNQKQMLEFCKSKDIVVVAYGVLG 242


>UniRef50_Q96UH3 Cluster: Aldehyde reductase; n=13;
           Pezizomycotina|Rep: Aldehyde reductase - Coccidioides
           posadasii
          Length = 314

 Score =  174 bits (424), Expect = 5e-42
 Identities = 81/172 (47%), Positives = 115/172 (66%)
 Frame = +1

Query: 136 LSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQEG 315
           L+ G  IP IG GTW+ +  +   AV  A+  GYRHI  A VYG EK +G A+       
Sbjct: 10  LNTGEDIPAIGFGTWQDENAQ-EDAVLTALSAGYRHIDTAAVYGTEKAIGRALA----RS 64

Query: 316 VVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTD 495
            + R++LFITSKLWN  HRP+ V  A++ SL+NL IDYLDLYL+HWP A+   D +FP D
Sbjct: 65  RLSRDELFITSKLWNNKHRPEDVEQAIDQSLKNLEIDYLDLYLMHWPAAFAPGDDMFPKD 124

Query: 496 ADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKP 651
           + G  +  D+DYVDT+KA+E LV  G  +++G+SNF+  +++R+L++ S+ P
Sbjct: 125 SQGNSKTVDIDYVDTYKAMEKLVKSGKTKAIGISNFSKGEMERLLESCSIVP 176


>UniRef50_A4RQH8 Cluster: Predicted protein; n=2; Ostreococcus|Rep:
           Predicted protein - Ostreococcus lucimarinus CCE9901
          Length = 337

 Score =  172 bits (419), Expect = 2e-41
 Identities = 83/170 (48%), Positives = 107/170 (62%)
 Frame = +1

Query: 139 SNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQEGV 318
           +NG +IP +G+GTWK++P EV  AV+DA+  GY H+ CA  Y NE EVGEA++   + G 
Sbjct: 11  ANGLRIPRVGLGTWKARPNEVRDAVRDALGAGYAHVDCAAAYANESEVGEALREAFERGD 70

Query: 319 VKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTDA 498
            KRED+F+TSKLWN   RP  VR AL  +L +L + YLDLYLIHWP A+K    + P DA
Sbjct: 71  AKREDVFVTSKLWNDRRRPRDVREALMTTLNDLGVGYLDLYLIHWPVAWKRGTVLQP-DA 129

Query: 499 DGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVK 648
           +  I        + W  LE  V  GLVR +GVSNFN  QL  + D+   K
Sbjct: 130 EASI-------AECWSELERCVADGLVRHIGVSNFNEAQLAALCDDPRTK 172


>UniRef50_Q2V420 Cluster: Uncharacterized protein At2g37770.1; n=1;
           Arabidopsis thaliana|Rep: Uncharacterized protein
           At2g37770.1 - Arabidopsis thaliana (Mouse-ear cress)
          Length = 283

 Score =  171 bits (415), Expect = 6e-41
 Identities = 84/172 (48%), Positives = 111/172 (64%)
 Frame = +1

Query: 136 LSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQEG 315
           L+ GAK P +G+GTW++ PG V  AV  A+ IGYRHI CA +YGNEKE+G  +K   ++ 
Sbjct: 10  LNTGAKFPSVGLGTWQASPGLVGDAVAAAVKIGYRHIDCAQIYGNEKEIGAVLKKLFEDR 69

Query: 316 VVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTD 495
           VVKREDLFITSKLW T H P  V  AL  +L++L ++Y+DLYLIHWP   K+       +
Sbjct: 70  VVKREDLFITSKLWCTDHDPQDVPEALNRTLKDLQLEYVDLYLIHWPARIKKGSVGIKPE 129

Query: 496 ADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKP 651
                    VD   TWKA+E L   G  R++GVSNF++K+L  +L+ A V P
Sbjct: 130 -----NLLPVDIPSTWKAMEALYDSGKARAIGVSNFSTKKLADLLELARVPP 176


>UniRef50_UPI0000498F1F Cluster: oxidoreductase, aldo/keto reductase
           family; n=2; Entamoeba histolytica HM-1:IMSS|Rep:
           oxidoreductase, aldo/keto reductase family - Entamoeba
           histolytica HM-1:IMSS
          Length = 305

 Score =  168 bits (409), Expect = 3e-40
 Identities = 97/241 (40%), Positives = 136/241 (56%)
 Frame = +1

Query: 133 TLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQE 312
           TL+NG KIP +G+GTW S  GEV +AV+ AI  GYRHI CA  YGNEKEVG+ IK+ I +
Sbjct: 6   TLNNGYKIPKLGLGTWMSANGEVGKAVEIAIKNGYRHIDCAKAYGNEKEVGDGIKSAIAK 65

Query: 313 GVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPT 492
           G VKRE+LF+T+KLW+T    + VR A   SL+ L ++YLDLY+IH P    +    F  
Sbjct: 66  GYVKREELFVTTKLWSTDKHKEDVRPACLESLKKLQLEYLDLYIIHIPLTADKKTGEFTE 125

Query: 493 DADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPGH*PGRM 672
           +         +   +TW+ +E LV  GLV+S+GVSNFN K+L+ +L  A ++P       
Sbjct: 126 EI--------IPIEETWREMEKLVEEGLVKSIGVSNFNIKKLEELLAIAKIQPAVNQFEF 177

Query: 673 PSVFKPXAIEAVLRRP*YYDNGVLPRWGXPDRPWAKPGDPHLMEDPKLKEIADRLGKXAA 852
              ++   +    ++   +  G  P       P    G P   E+  +K IA +  K AA
Sbjct: 178 HIYYQRPKLHQFCKKHNIHITGYCPL----GNPGISSGVPAPFENEVVKAIAKKHNKKAA 233

Query: 853 Q 855
           Q
Sbjct: 234 Q 234


>UniRef50_Q0IBY6 Cluster: Alcohol dehydrogenase; n=2;
           Chroococcales|Rep: Alcohol dehydrogenase - Synechococcus
           sp. (strain CC9311)
          Length = 336

 Score =  167 bits (406), Expect = 7e-40
 Identities = 95/252 (37%), Positives = 147/252 (58%), Gaps = 3/252 (1%)
 Frame = +1

Query: 109 IMTSVPVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGE 288
           ++ ++   +LSNG ++P++G+GT KS+  +V ++V++AI IGYRHI CA +YGNE+EVG+
Sbjct: 15  VIPTMQYASLSNGDRMPLLGLGTGKSESRQVYKSVREAIKIGYRHIDCASIYGNEEEVGD 74

Query: 289 AIKTKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYK 468
           AI+  IQ   + R +L+ITSKLW+  H  + V  AL  SL+NL +DYL+LYLIHWP   +
Sbjct: 75  AIRDAIQNHEITRSELWITSKLWSNCHGKNHVEAALSQSLQNLGVDYLNLYLIHWPVGIR 134

Query: 469 EDDAIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVK 648
            +   F    D  +   +    +TW+A+E     GL + +GVSNF  K+LQ+++ +   K
Sbjct: 135 PEKT-FAESVDDLLTPEESPISETWEAMESTRDKGLTKHIGVSNFTVKKLQQLVSHCKQK 193

Query: 649 PG-H*PGRMPSVFKPXAIEAVLRRP*YYDNGVLPRWGXPDRPWA-KPGD-PHLMEDPKLK 819
           P  +     P + +P  IE              P  G  DRP + K  D P +++ P ++
Sbjct: 194 PEVNQVEHHPLLQQPTLIEYCASEE-ILITAYSP-LGSMDRPQSLKVKDAPAVLDHPVIR 251

Query: 820 EIADRLGKXAAQ 855
            IA+  G   AQ
Sbjct: 252 AIAETRGCSPAQ 263


>UniRef50_UPI0000D9A956 Cluster: PREDICTED: similar to aldo-keto
           reductase family 1, member B10, partial; n=1; Macaca
           mulatta|Rep: PREDICTED: similar to aldo-keto reductase
           family 1, member B10, partial - Macaca mulatta
          Length = 275

 Score =  167 bits (405), Expect = 9e-40
 Identities = 104/234 (44%), Positives = 134/234 (57%), Gaps = 9/234 (3%)
 Frame = +1

Query: 181 KSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQEGVVKREDLFITSK--- 351
           KS  G+V +AVK AID GYRHI CA+VY NE EVGEAI+ KIQE  VKREDLFI SK   
Sbjct: 42  KSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEKIQEQAVKREDLFIVSKVHM 101

Query: 352 ---LWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTDADGKIQFSD 522
              LW TF    LVR A E +L++L + YLD+YLIHWPQ +K                  
Sbjct: 102 AHWLWTTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFK------------------ 143

Query: 523 VDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPGH*PGRMPSVFKPXAIE 702
                   A+E LV  GLV++LG+SNFN  Q++++L+   +K  + P        P   +
Sbjct: 144 --------AMEELVDEGLVKALGISNFNHFQIEKLLNKPGLK--YKPVTNQVECHPYLTQ 193

Query: 703 AVLRRP*YYDNGVLPRW---GXPDRPWAKPGDPHLMEDPKLKEIADRLGKXAAQ 855
             L +  +     +  +   G PDRPWAKP DP L+E+PK+KEIA +  K  AQ
Sbjct: 194 EKLIQYCHSKGITITAYSPLGSPDRPWAKPEDPSLLEEPKIKEIAAKHKKTTAQ 247



 Score = 52.0 bits (119), Expect = 4e-05
 Identities = 21/34 (61%), Positives = 25/34 (73%)
 Frame = +2

Query: 653 VTNQVECHPYLNXKRLKQFCEDRDIMITXYSPXG 754
           VTNQVECHPYL  ++L Q+C  + I IT YSP G
Sbjct: 181 VTNQVECHPYLTQEKLIQYCHSKGITITAYSPLG 214


>UniRef50_Q7QVQ9 Cluster: GLP_302_44328_45269; n=1; Giardia lamblia
           ATCC 50803|Rep: GLP_302_44328_45269 - Giardia lamblia
           ATCC 50803
          Length = 313

 Score =  166 bits (403), Expect = 2e-39
 Identities = 77/169 (45%), Positives = 111/169 (65%), Gaps = 4/169 (2%)
 Frame = +1

Query: 157 PVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQEGV--VKRE 330
           P +G GTW++ P  V  AV+ A+  GYRHI CA+VY NE+ +G A     ++    +KRE
Sbjct: 5   PRLGFGTWQAPPEAVQTAVETALMTGYRHIDCAYVYQNEEAIGRAFGKIFKDASSGIKRE 64

Query: 331 DLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDA--IFPTDADG 504
           D++ITSKLWN  HRP+LVR   + ++ +L +DYLDL+L+HWP A+  +D   +FP DA+G
Sbjct: 65  DVWITSKLWNYNHRPELVREQCKKTMSDLQVDYLDLFLVHWPLAFVRNDVGDLFPKDAEG 124

Query: 505 KIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKP 651
           +     V   DTW+A+E LV  GLV+ +GVSN+    L  +L+ A +KP
Sbjct: 125 RAMLEKVPLADTWRAMEQLVEEGLVKHIGVSNYTVPLLADLLNYAKIKP 173



 Score = 36.7 bits (81), Expect = 1.7
 Identities = 16/40 (40%), Positives = 21/40 (52%)
 Frame = +2

Query: 653 VTNQVECHPYLNXKRLKQFCEDRDIMITXYSPXGXLPTDP 772
           + NQ+E HP+       +FC D  I +T YSP G    DP
Sbjct: 174 LVNQIEIHPWHPNDATVKFCLDNGIGVTAYSPMGGSYADP 213


>UniRef50_A3U9Y0 Cluster: Aldehyde reductase; n=5;
           Bacteroidetes|Rep: Aldehyde reductase - Croceibacter
           atlanticus HTCC2559
          Length = 316

 Score =  165 bits (400), Expect = 4e-39
 Identities = 91/240 (37%), Positives = 132/240 (55%), Gaps = 4/240 (1%)
 Frame = +1

Query: 127 VTTLS--NGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKT 300
           +TTL   +G  IP IG+GTWKS P +V +AVK A++ GY+HI CA  Y NE  VGEA K 
Sbjct: 1   MTTLKFRDGDSIPSIGLGTWKSDPEDVKKAVKIALENGYKHIDCAAAYDNEDAVGEAFKE 60

Query: 301 KIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDA 480
             + G VKRED+F+TSKLWN  H+ + V  AL+ +L++LN+DYLDLYL+HWP A+K    
Sbjct: 61  SFESGNVKREDIFVTSKLWNNAHKKEDVIPALKKTLKDLNLDYLDLYLMHWPVAFKPSVN 120

Query: 481 IFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPGH* 660
            FP   +  +   +    +T  A+      GL++ +GVSNF+ ++L+ +       P   
Sbjct: 121 GFPEKDEDYLSLEEAPLHETLNAMIEAKKQGLIKHVGVSNFSKEKLESLKGKVEEMPEMN 180

Query: 661 PGRMPSVFKPXAIEAVLRRP*YYDNGVLPRWGXPDRPWAKPGD--PHLMEDPKLKEIADR 834
              +        + +   +      G  P  G  DR      D  P L ED  +K++A+R
Sbjct: 181 QVELHPYLPQNDLYSYCSKEGILLTGYSP-LGSGDRSEGMKADDEPSLFEDDTIKKVAER 239


>UniRef50_A2R6Z3 Cluster: Catalytic activity: an alcohol + NADP(+)
           <=> an aldehyde + NADPH; n=9; Pezizomycotina|Rep:
           Catalytic activity: an alcohol + NADP(+) <=> an aldehyde
           + NADPH - Aspergillus niger
          Length = 345

 Score =  164 bits (399), Expect = 5e-39
 Identities = 83/174 (47%), Positives = 111/174 (63%), Gaps = 2/174 (1%)
 Frame = +1

Query: 136 LSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQEG 315
           L+ G  +P +G+GTW+SK  EV  AV  A+  GYRHI  A VYGNE+EVG+ ++      
Sbjct: 9   LNTGYDMPAVGLGTWQSKKDEVRDAVIAALKCGYRHIDAAAVYGNEQEVGDGMRLS---- 64

Query: 316 VVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYK-EDDAIFP- 489
            V RE++F+TSKLWNT H P+ V  A++ SL +L  DYLDLYLIHWP A++     I P 
Sbjct: 65  GVPREEIFLTSKLWNTHHHPENVEEAVDKSLADLQTDYLDLYLIHWPVAFRYSTTTIQPV 124

Query: 490 TDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKP 651
            +  G I   DV   DTW A+E LV  G VRS+GVSNF  ++++ +L  A + P
Sbjct: 125 NEQTGLIDVVDVPIKDTWAAMEKLVEKGKVRSIGVSNFTREKIEELLKTAKITP 178


>UniRef50_Q22352 Cluster: Putative uncharacterized protein T08H10.1;
           n=2; Caenorhabditis|Rep: Putative uncharacterized
           protein T08H10.1 - Caenorhabditis elegans
          Length = 333

 Score =  162 bits (393), Expect = 3e-38
 Identities = 95/258 (36%), Positives = 149/258 (57%), Gaps = 8/258 (3%)
 Frame = +1

Query: 106 LIMTSVPVTTLSNGAKIPVIGIGTWKSKP-GEVTQAVKDAIDIGYRHIXCAFVYGNEKEV 282
           + + S+P+ T   GA++P+ G+GTW+ K   E+T A++ A+D GYR I  A +Y NE  +
Sbjct: 1   MTVDSIPLNT---GAQLPLFGLGTWQVKDEAELTVALRAALDAGYRLIDTAHLYQNEHII 57

Query: 283 GEAIKTKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQA 462
           G+ +   I  G +KRED+F+TSKL  T H P+ V   +E  L+ L ++Y+DLYLIH P  
Sbjct: 58  GKVLHEYISSGKLKREDIFVTSKLPFTAHAPEDVPKCVESQLKALQLEYIDLYLIHCPFP 117

Query: 463 YKEDDAIF-PTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNA 639
           +K  +  F P   +G++  +++ ++DTW+ALE L   G +++LGVSNF+  QLQ + D A
Sbjct: 118 FKHQEGSFAPLMENGELAVTEIAHIDTWRALEKLYKEGKLKALGVSNFSCNQLQALYDAA 177

Query: 640 SVKPGH*PGRMPSVFKPXAIEAVLRRP*YYDNGVLPRWGXPDRPWAKP------GDPHLM 801
            VKP +        +    + A+ ++         P  G P R  A+P      GDP L 
Sbjct: 178 EVKPANQQVECHIYWPQQELRALCKKLGVTVTAYAP-LGSPGRKAARPDGVWPEGDPLL- 235

Query: 802 EDPKLKEIADRLGKXAAQ 855
            +P +K++A +  K AAQ
Sbjct: 236 -EPIVKQLAAKYHKTAAQ 252


>UniRef50_Q2UGR1 Cluster: Aldo/keto reductase family proteins; n=2;
           Ascomycota|Rep: Aldo/keto reductase family proteins -
           Aspergillus oryzae
          Length = 323

 Score =  160 bits (389), Expect = 8e-38
 Identities = 92/241 (38%), Positives = 129/241 (53%), Gaps = 2/241 (0%)
 Frame = +1

Query: 136 LSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQEG 315
           L++G  IP IG+GTW SKP EV  AV+ A+  GYRHI  A  Y NE EVG   K    + 
Sbjct: 9   LNSGYNIPAIGLGTWLSKPHEVENAVEAALRAGYRHIDAAACYQNENEVGNGWK----KS 64

Query: 316 VVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKE-DDAIFPT 492
            V R+ +FITSKLWNT H P+ V  A+  +L++L  DYLDLYLIHWP A++  ++ + P 
Sbjct: 65  GVPRDQIFITSKLWNTHHHPEHVEEAVNKTLKDLQTDYLDLYLIHWPVAFEHTNETLTPI 124

Query: 493 D-ADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPGH*PGR 669
           D    + + ++V   DTW ALE LV    +RS+G+SNF   ++  +L  A + P      
Sbjct: 125 DPVTKRFRLANVPIADTWAALEKLVEAKKIRSIGISNFTQDKIDDLLKTAKIPPAVNQIE 184

Query: 670 MPSVFKPXAIEAVLRRP*YYDNGVLPRWGXPDRPWAKPGDPHLMEDPKLKEIADRLGKXA 849
                +   +   L+          P              P +++DP +K IAD+LGK  
Sbjct: 185 AHPYLQQPGLHKYLKEKNILSVAYSPLGNNIYNA------PRVVDDPDVKAIADKLGKDP 238

Query: 850 A 852
           A
Sbjct: 239 A 239



 Score = 35.9 bits (79), Expect = 3.0
 Identities = 13/32 (40%), Positives = 21/32 (65%)
 Frame = +2

Query: 659 NQVECHPYLNXKRLKQFCEDRDIMITXYSPXG 754
           NQ+E HPYL    L ++ ++++I+   YSP G
Sbjct: 181 NQIEAHPYLQQPGLHKYLKEKNILSVAYSPLG 212


>UniRef50_A2EYY6 Cluster: Oxidoreductase, aldo/keto reductase family
           protein; n=9; Trichomonas vaginalis G3|Rep:
           Oxidoreductase, aldo/keto reductase family protein -
           Trichomonas vaginalis G3
          Length = 308

 Score =  159 bits (386), Expect = 2e-37
 Identities = 95/245 (38%), Positives = 138/245 (56%), Gaps = 10/245 (4%)
 Frame = +1

Query: 151 KIPVIGIGTWKSKPGE-----VTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQEG 315
           +IP IG+GTWKS   E     +T A+K+A   GY HI CA  Y NE  VG+A++     G
Sbjct: 3   RIPTIGLGTWKSPRSEDLVNAITYAIKEA---GYVHIDCALCYENEDIVGQALQQCWDSG 59

Query: 316 VVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKE---DDAIF 486
           + KRE+++ITSKLWNT HR ++V  A   +L++L +DYLDLYL+H+P A++      ++ 
Sbjct: 60  I-KRENIWITSKLWNTHHRLEIVEEACRKTLKDLRLDYLDLYLMHYPFAFQNTGIGGSLN 118

Query: 487 PTDADGKIQFSD-VDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRI-LDNASVKPGH* 660
           P D  G   F D V  +DTWKA+E LV  GLV+ +GVSN+   QL+R+   +A   P   
Sbjct: 119 PLDEKGNTIFDDGVSLIDTWKAMEKLVEKGLVKRIGVSNWTINQLERLKYSDAKTTPYTN 178

Query: 661 PGRMPSVFKPXAIEAVLRRP*YYDNGVLPRWGXPDRPWAKPGDPHLMEDPKLKEIADRLG 840
                   +   +   + +      G     G PD  WAKP +P +++D +L +IA   G
Sbjct: 179 QVEFNLYMQQGPLREYMHKEGIIVTG-YSTLGTPD--WAKPDEPVVLKDEELNKIAAETG 235

Query: 841 KXAAQ 855
           K   +
Sbjct: 236 KSVGE 240


>UniRef50_P38715 Cluster: NADPH-dependent aldose reductase GRE3;
           n=39; cellular organisms|Rep: NADPH-dependent aldose
           reductase GRE3 - Saccharomyces cerevisiae (Baker's
           yeast)
          Length = 327

 Score =  159 bits (386), Expect = 2e-37
 Identities = 82/185 (44%), Positives = 115/185 (62%), Gaps = 10/185 (5%)
 Frame = +1

Query: 127 VTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKI 306
           + TL+NG K+P++G+G WK         + +AI +GYR    A  YGNEKEVGE I+  I
Sbjct: 4   LVTLNNGLKMPLVGLGCWKIDKKVCANQIYEAIKLGYRLFDGACDYGNEKEVGEGIRKAI 63

Query: 307 QEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYK------ 468
            EG+V R+D+F+ SKLWN FH PD V+ AL+ +L ++ +DYLDLY IH+P A+K      
Sbjct: 64  SEGLVSRKDIFVVSKLWNNFHHPDHVKLALKKTLSDMGLDYLDLYYIHFPIAFKYVPFEE 123

Query: 469 EDDAIFPTDAD----GKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDN 636
           +    F T AD    G I  + V  +DT++ALE  V  GL++S+GVSNF    +Q +L  
Sbjct: 124 KYPPGFYTGADDEKKGHITEAHVPIIDTYRALEECVDEGLIKSIGVSNFQGSLIQDLLRG 183

Query: 637 ASVKP 651
             +KP
Sbjct: 184 CRIKP 188



 Score = 36.3 bits (80), Expect = 2.2
 Identities = 15/34 (44%), Positives = 20/34 (58%)
 Frame = +2

Query: 653 VTNQVECHPYLNXKRLKQFCEDRDIMITXYSPXG 754
           V  Q+E HPYL  + L +FC+  DI +  YS  G
Sbjct: 189 VALQIEHHPYLTQEHLVEFCKLHDIQVVAYSSFG 222


>UniRef50_Q1IN88 Cluster: Aldehyde reductase; n=5; Bacteria|Rep:
           Aldehyde reductase - Acidobacteria bacterium (strain
           Ellin345)
          Length = 313

 Score =  159 bits (385), Expect = 2e-37
 Identities = 92/242 (38%), Positives = 134/242 (55%), Gaps = 2/242 (0%)
 Frame = +1

Query: 136 LSNGA-KIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQE 312
           L +GA  IP +G GT  + P     A +DA+  G+RH  CA  Y NE+EVGEA++     
Sbjct: 13  LHHGAGHIPALGFGTLIADPALTITATRDALAAGFRHFDCAERYRNEREVGEALRAGRAA 72

Query: 313 GVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPT 492
           G + RE++F+T+KLWNT HRP+ V  A E SL  L +DYLDLYLIH P A++  D   P 
Sbjct: 73  GNIAREEIFVTTKLWNTNHRPERVEPAFEASLDRLGLDYLDLYLIHTPFAFQPGDEQDPR 132

Query: 493 DADGKIQFSD-VDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPGH*PGR 669
           D +G + + + V   +TW ALE LV  G  R++G+S+ +  +L  I + A +KP      
Sbjct: 133 DQNGSVIYDEGVTLRETWSALENLVDRGRCRAIGLSDISMDRLAPIYEAARIKPAVVQVE 192

Query: 670 MPSVFKPXAIEAVLRRP*YYDNGVLPRWGXPDRPWAKPGDPHLMEDPKLKEIADRLGKXA 849
                    +    +R     NG++     P     +PG   L+EDP +  +++R+GK A
Sbjct: 193 SHPYLPETELLEFCKR-----NGIVLLAFAPLGHGMRPG---LLEDPVITSVSERVGKTA 244

Query: 850 AQ 855
           AQ
Sbjct: 245 AQ 246


>UniRef50_Q9U2J5 Cluster: Putative uncharacterized protein; n=2;
           Caenorhabditis|Rep: Putative uncharacterized protein -
           Caenorhabditis elegans
          Length = 339

 Score =  158 bits (383), Expect = 4e-37
 Identities = 84/253 (33%), Positives = 133/253 (52%), Gaps = 5/253 (1%)
 Frame = +1

Query: 112 MTSVPVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEA 291
           M      TL++G ++PVIG GTW+       + V+DA++ GYRHI  A  + N++EV   
Sbjct: 1   MPIADTVTLNSGYEMPVIGYGTWQLPKNLAAERVRDALEAGYRHIDSALSFKNQEEVAAG 60

Query: 292 IKTKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKE 471
           IK   +   V+RE+LF++SK+WNT+H  +     ++  L      Y+DL +IHWP  + E
Sbjct: 61  IKDWCKIRKVRREELFLSSKIWNTYHSRNRCMQQIDEMLEIFETTYMDLIVIHWPFGWAE 120

Query: 472 DD-----AIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDN 636
           D+      ++P  A+GK+++SDVDY++TWKALE     G +RS+G++NFN  Q++++   
Sbjct: 121 DEPPGERGLWPRGANGKMRYSDVDYLETWKALEDAHRSGKIRSIGLANFNIGQVEQVWTK 180

Query: 637 ASVKPGH*PGRMPSVFKPXAIEAVLRRP*YYDNGVLPRWGXPDRPWAKPGDPHLMEDPKL 816
             +KP      M        I    R         +         + K  DP+L+ +  L
Sbjct: 181 GLIKPAVLQVEMNPFLDQEEIRQFCREKGIILTAFMLTGNPGSALYRKHEDPNLLYNETL 240

Query: 817 KEIADRLGKXAAQ 855
           + IA   GK   Q
Sbjct: 241 QSIAKGHGKSVVQ 253


>UniRef50_A2FPE2 Cluster: Oxidoreductase, aldo/keto reductase family
           protein; n=3; Trichomonas vaginalis G3|Rep:
           Oxidoreductase, aldo/keto reductase family protein -
           Trichomonas vaginalis G3
          Length = 309

 Score =  158 bits (383), Expect = 4e-37
 Identities = 91/241 (37%), Positives = 142/241 (58%), Gaps = 7/241 (2%)
 Frame = +1

Query: 154 IPVIGIGTWKSK-PGEVTQAVKDAI-DIGYRHIXCAFVYGNEKEVGEAIKTKIQEGVVKR 327
           IP IG+GT+ ++ P  +  AV  AI D GYRH+ CA  Y N++ +GEA+     +G VKR
Sbjct: 4   IPSIGLGTFLAEDPAALKAAVHSAIEDSGYRHVDCAAYYKNQEIIGEALSEIFAKGQVKR 63

Query: 328 EDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAY--KEDDAIFPTDAD 501
           E+++ITSK+WNT HRPDL+   ++ +L+ L ++YLDL L+HW  A+  +EDD   P D  
Sbjct: 64  EEVWITSKVWNTKHRPDLLVKDVKKTLKELKLEYLDLVLVHWACAFQSREDDEYLPRDET 123

Query: 502 GKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPGH*PGRMPS- 678
           GKI   ++D ++TWKA+E     GL + +GVSNF+ +QL+R+  +  VK      ++ S 
Sbjct: 124 GKIITENIDILETWKAMEECYNLGLAKHIGVSNFSIEQLERMRYDPGVKIQPYCNQVESH 183

Query: 679 --VFKPXAIEAVLRRP*YYDNGVLPRWGXPDRPWAKPGDPHLMEDPKLKEIADRLGKXAA 852
             + +   ++ + +R  Y  +           P+  P    L++DP L E+A  +GK  A
Sbjct: 184 MYLQQQPMLDYLTQRKMYMISYTCLGRATLKGPYGYP----LLQDPVLNEVAKEIGKTPA 239

Query: 853 Q 855
           Q
Sbjct: 240 Q 240


>UniRef50_Q4PAT5 Cluster: Putative uncharacterized protein; n=1;
           Ustilago maydis|Rep: Putative uncharacterized protein -
           Ustilago maydis (Smut fungus)
          Length = 700

 Score =  157 bits (382), Expect = 6e-37
 Identities = 78/179 (43%), Positives = 115/179 (64%), Gaps = 6/179 (3%)
 Frame = +1

Query: 133 TLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQE 312
           TL+NGA+IP +G GTWK    + T AV  AI  GYRHI CA+ Y NE    +A+   I++
Sbjct: 13  TLANGAQIPKLGFGTWKMSKEQATPAVAHAIKTGYRHIDCAWAYRNE----DAVAAGIKK 68

Query: 313 GVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAY-KEDDAIFP 489
             V R  L++TSKLWN+FH P+ V  AL+ SL++L  DYLDLYL+HWP A+     ++ P
Sbjct: 69  AGVPRSQLWLTSKLWNSFHHPEHVEKALDASLKDLGTDYLDLYLMHWPVAFLNSKGSMVP 128

Query: 490 ---TDADGKIQFSDV--DYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKP 651
              +     ++  D+  D++ T++ +E +V  G VR++GVSNFN ++   ++D AS+KP
Sbjct: 129 SIRSTGGHPVESEDLSRDFMATYRVMEEMVKKGKVRNIGVSNFNIRRTSEVVDEASIKP 187


>UniRef50_Q8SSK6 Cluster: ALDOSE REDUCTASE; n=1; Encephalitozoon
           cuniculi|Rep: ALDOSE REDUCTASE - Encephalitozoon
           cuniculi
          Length = 301

 Score =  157 bits (380), Expect = 1e-36
 Identities = 76/173 (43%), Positives = 103/173 (59%), Gaps = 1/173 (0%)
 Frame = +1

Query: 136 LSNGAKIPVIGIGTWKSKPGEVTQ-AVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQE 312
           L+NG +IP +G+GTW  +   V + A+++A+ +GYRHI  AF+YGNEK +G  +K    E
Sbjct: 8   LNNGKEIPTVGLGTWGMEDEAVLEGAIRNALSLGYRHIDTAFIYGNEKMIGNILKKLFDE 67

Query: 313 GVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPT 492
           GVV+R+DLFITSKLWNTFH        L  SL +L +DY+DLYLIHWP  +         
Sbjct: 68  GVVQRKDLFITSKLWNTFH--GCPEDGLRRSLNDLQMDYVDLYLIHWPVTFDPAPDGTVE 125

Query: 493 DADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKP 651
               K      D V  WK +E LV  GL +S+G+SNF     ++IL    + P
Sbjct: 126 SCGKKYNVGKFDAVGVWKKMEALVDLGLAKSIGISNFGKANTEKILGTCRICP 178



 Score = 37.9 bits (84), Expect = 0.73
 Identities = 15/34 (44%), Positives = 20/34 (58%)
 Frame = +2

Query: 662 QVECHPYLNXKRLKQFCEDRDIMITXYSPXGXLP 763
           Q+E HPYLN K L +F + + I +  YS  G  P
Sbjct: 182 QIELHPYLNQKELVEFMKSKGIQVISYSSLGSAP 215


>UniRef50_Q55FL3 Cluster: Aldo-keto reductase; n=2; Dictyostelium
           discoideum AX4|Rep: Aldo-keto reductase - Dictyostelium
           discoideum AX4
          Length = 321

 Score =  156 bits (379), Expect = 1e-36
 Identities = 81/178 (45%), Positives = 115/178 (64%), Gaps = 6/178 (3%)
 Frame = +1

Query: 136 LSNGAKIPVIGIGTWKSK-PGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQE 312
           L++G +IP IG+GT+ S+ PGEV  A+ +A+  GYRHI  A  YGNEK +G ++K   +E
Sbjct: 19  LNDGNQIPSIGLGTYYSENPGEVGDAINNALKNGYRHIDGAAFYGNEKVIGNSLKEIFKE 78

Query: 313 GVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPT 492
           G +KRED+F TSKLWN+ H  +LV      ++ +L I YLDLYLIHWP A++  + +  T
Sbjct: 79  GEIKREDIFYTSKLWNSCHNSNLVVKHCVKTIEDLGIGYLDLYLIHWPIAFENSNPLGLT 138

Query: 493 -----DADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKP 651
                D +G    + V   +TW+ +E LV  GLV+S+GVSNFN + L  +L  A +KP
Sbjct: 139 IEPLRDQNGNPIIAPVSIRETWQEMEKLVELGLVKSIGVSNFNVQNLVDLLTYAKIKP 196



 Score = 41.9 bits (94), Expect = 0.045
 Identities = 16/34 (47%), Positives = 23/34 (67%)
 Frame = +2

Query: 653 VTNQVECHPYLNXKRLKQFCEDRDIMITXYSPXG 754
           V NQVE HPYL   +L+++C+  +I +  YSP G
Sbjct: 197 VVNQVEIHPYLTQFKLQEYCDKYEIKLVAYSPLG 230


>UniRef50_Q7ZA52 Cluster: Aldose reductase; n=6; Pezizomycotina|Rep:
           Aldose reductase - Magnaporthe grisea (Rice blast
           fungus) (Pyricularia grisea)
          Length = 312

 Score =  156 bits (378), Expect = 2e-36
 Identities = 80/177 (45%), Positives = 112/177 (63%), Gaps = 4/177 (2%)
 Frame = +1

Query: 133 TLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQE 312
           TL+ GAKIP  G+GTW+   G + +AV  AI  GYR I  A+VYGNE+EVG+ I+  I  
Sbjct: 7   TLNTGAKIPAFGLGTWQGDKGVIKEAVLTAIKSGYRLIDGAYVYGNEEEVGQGIREAISS 66

Query: 313 GVVKREDLFITSKLWNTF-HRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKED--DAI 483
           G+VKREDLF+ SK W T+  R +L    L+ SL+ L +DY+DLYL+HWP     +  D  
Sbjct: 67  GIVKREDLFVVSKCWATYTTRCEL---GLDQSLKLLGLDYVDLYLVHWPILMNPEGNDEK 123

Query: 484 FPTDADGKIQFSDV-DYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKP 651
           FP  ADG        ++VDTWK +E L   G  +++GVSN++   L+++L +A+  P
Sbjct: 124 FPKHADGSRDIIHTHNHVDTWKLMEKLPATGKTKAVGVSNYSKAWLEQLLPHATTVP 180



 Score = 36.7 bits (81), Expect = 1.7
 Identities = 16/32 (50%), Positives = 20/32 (62%)
 Frame = +2

Query: 659 NQVECHPYLNXKRLKQFCEDRDIMITXYSPXG 754
           NQVE HP L  + L  FC+++ I I  YSP G
Sbjct: 183 NQVENHPQLPQQELVDFCKEKGIHIMAYSPLG 214


>UniRef50_A2QVE5 Cluster: Similarity: shows similarity to several
           dehydrogenases of different specificities; n=4;
           Pezizomycotina|Rep: Similarity: shows similarity to
           several dehydrogenases of different specificities -
           Aspergillus niger
          Length = 381

 Score =  156 bits (378), Expect = 2e-36
 Identities = 79/180 (43%), Positives = 111/180 (61%), Gaps = 7/180 (3%)
 Frame = +1

Query: 133 TLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQE 312
           TL++GA+IP +G GTW+S PG+V  AV +A+  GYRH+  A +Y N++EV E IK   ++
Sbjct: 8   TLNSGAQIPQLGFGTWQSAPGQVGDAVYEALKAGYRHLDLATIYQNQREVAEGIKRAYKD 67

Query: 313 GV-VKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFP 489
              +KRED+FITSKLWN+ H P +V  AL+  L  L +DYLDLYL+HWP ++     +FP
Sbjct: 68  VPGLKREDIFITSKLWNSQHDPAVVEKALDECLAELELDYLDLYLVHWPVSFTTGSELFP 127

Query: 490 TDADGKIQFSDV------DYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKP 651
              D  ++  DV        VDTWKA+  L      R++GVSN     L+ I++   V P
Sbjct: 128 LVKDSSVEGGDVVINDDISIVDTWKAMTQLP-KSKARTVGVSNHMIPHLEAIINATGVVP 186


>UniRef50_Q7PLK6 Cluster: CG40064-PA; n=1; Drosophila
           melanogaster|Rep: CG40064-PA - Drosophila melanogaster
           (Fruit fly)
          Length = 361

 Score =  155 bits (377), Expect = 2e-36
 Identities = 73/154 (47%), Positives = 107/154 (69%), Gaps = 2/154 (1%)
 Frame = +1

Query: 196 EVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQEGVVKREDLFITSKLWNTFHRP 375
           + + AV  AI+ G+RH   A+ Y NEKE+GEA++T+I+ G + RE++F+T+KLWNT H P
Sbjct: 45  QCSAAVHCAIETGFRHFDTAYYYENEKEIGEALRTQIKMGNISRENIFLTTKLWNTHHDP 104

Query: 376 DLVRGALEVSLRNLNIDYLDLYLIHWPQAYKE--DDAIFPTDADGKIQFSDVDYVDTWKA 549
             VR   E  L  L   Y+DLYL+H+P  YK   D+ + P   D ++Q  ++DY+DTW+A
Sbjct: 105 RDVRRICEKQLELLGFSYIDLYLMHFPVGYKYVCDEILMPMSGD-ELQTVEIDYLDTWRA 163

Query: 550 LEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKP 651
           +E LV  G+VRS+G+SNFN +Q+QRI+  +S KP
Sbjct: 164 MENLVKLGMVRSIGLSNFNMEQIQRIIQCSSSKP 197


>UniRef50_Q7ZWA4 Cluster: Zgc:56622; n=6; cellular organisms|Rep:
           Zgc:56622 - Danio rerio (Zebrafish) (Brachydanio rerio)
          Length = 289

 Score =  154 bits (374), Expect = 5e-36
 Identities = 72/150 (48%), Positives = 101/150 (67%), Gaps = 1/150 (0%)
 Frame = +1

Query: 205 QAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQEGVVKREDLFITSKLWNTFHRPDLV 384
           +A + AI  GYRHI  AF Y NE +VG AI+ KIQ+G+++R+D+FI SKLW T H P+ +
Sbjct: 4   RACEAAIAAGYRHIDTAFCYRNEVDVGMAIQNKIQQGIIRRQDMFIVSKLWGTHHAPEDI 63

Query: 385 RGALEVSLRNLNIDYLDLYLIHWPQAYKE-DDAIFPTDADGKIQFSDVDYVDTWKALEPL 561
                 SL +L +DYLD YL+H+P   K+  D +FP + DGKI  +D+DYVD W+ +E L
Sbjct: 64  PVCFNKSLSDLQLDYLDQYLVHFPVGLKKVGDELFP-ERDGKILTTDIDYVDVWRGMEAL 122

Query: 562 VCHGLVRSLGVSNFNSKQLQRILDNASVKP 651
              G V+S+GVSNF  +Q+ R+L  A + P
Sbjct: 123 KATGKVKSIGVSNFTMEQIDRLLSVAKIPP 152



 Score = 37.5 bits (83), Expect = 0.97
 Identities = 15/32 (46%), Positives = 21/32 (65%)
 Frame = +2

Query: 659 NQVECHPYLNXKRLKQFCEDRDIMITXYSPXG 754
           NQVE HPYL    L  +C+ ++I +T +SP G
Sbjct: 155 NQVELHPYLVQSDLIDYCKSKNIALTAHSPFG 186


>UniRef50_Q9VHX4 Cluster: CG2767-PA; n=4; Endopterygota|Rep:
           CG2767-PA - Drosophila melanogaster (Fruit fly)
          Length = 329

 Score =  154 bits (374), Expect = 5e-36
 Identities = 75/184 (40%), Positives = 112/184 (60%), Gaps = 2/184 (1%)
 Frame = +1

Query: 112 MTSVPVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEA 291
           M +    T +NG K+PVIGIGTW++   E+  A+  A++ GYRHI  A VYGNEK +G  
Sbjct: 1   MVNTKFLTFNNGEKMPVIGIGTWQASDEEIETAIDAALEAGYRHIDTAPVYGNEKAIGRV 60

Query: 292 IKTKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYK- 468
           +K  +  G VKRE+LFI +K+    +RP  V   ++ SL +L +DY+DLYL+H P     
Sbjct: 61  LKRWLDAGKVKREELFIVTKVPPVSNRPHEVEPTIKKSLEDLQLDYVDLYLVHTPFTINI 120

Query: 469 EDDAIFPTDADGKIQFS-DVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASV 645
            +D  F  D +G ++     ++   W A+E LV  GL +S+GVSNF+  Q+ R+L N  +
Sbjct: 121 NEDGSFKLDKEGLMEVDVTTNHAAIWVAMEALVEKGLTKSIGVSNFSKDQVARLLKNCKI 180

Query: 646 KPGH 657
           +P +
Sbjct: 181 RPAN 184



 Score = 37.9 bits (84), Expect = 0.73
 Identities = 15/32 (46%), Positives = 20/32 (62%)
 Frame = +2

Query: 659 NQVECHPYLNXKRLKQFCEDRDIMITXYSPXG 754
           NQ+E H YL  + L  FC+  +I +T YSP G
Sbjct: 185 NQIEHHVYLQQRDLVDFCKSENITVTAYSPLG 216


>UniRef50_Q9Y020 Cluster: 3-dehydroecdysone 3beta-reductase
           precursor; n=1; Spodoptera littoralis|Rep:
           3-dehydroecdysone 3beta-reductase precursor - Spodoptera
           littoralis (Egyptian cotton leafworm)
          Length = 345

 Score =  153 bits (371), Expect = 1e-35
 Identities = 76/186 (40%), Positives = 112/186 (60%), Gaps = 9/186 (4%)
 Frame = +1

Query: 121 VPVTTLSNGAKIPVIGIGTW---------KSKPGEVTQAVKDAIDIGYRHIXCAFVYGNE 273
           VP+  + N  ++P I +GT+          SK  ++   V  AID+GYRH   A +Y  E
Sbjct: 22  VPMLKMLNDREMPAIALGTYLGFDKGGAVTSKDKQLRNVVMQAIDLGYRHFDTAAIYNTE 81

Query: 274 KEVGEAIKTKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHW 453
            EVGEAI+ KI EGV+KRED+F+T+KLWNT H+ + V  A++ +L    +DY+DL+L+HW
Sbjct: 82  AEVGEAIRMKIDEGVIKREDVFLTTKLWNTHHKREQVAVAMKETLNKTGLDYVDLFLMHW 141

Query: 454 PQAYKEDDAIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILD 633
           P A  ED              S+ DY++TW+A E +V  G  +S+G+SNFN  Q+  +L 
Sbjct: 142 PIALNED-----------YSHSNTDYLETWRATEEMVKLGYTKSIGLSNFNKLQVATVLQ 190

Query: 634 NASVKP 651
             ++KP
Sbjct: 191 ECTIKP 196


>UniRef50_Q16K66 Cluster: Aldo-keto reductase; n=2; Aedes
           aegypti|Rep: Aldo-keto reductase - Aedes aegypti
           (Yellowfever mosquito)
          Length = 303

 Score =  152 bits (369), Expect = 2e-35
 Identities = 90/243 (37%), Positives = 136/243 (55%), Gaps = 3/243 (1%)
 Frame = +1

Query: 136 LSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQEG 315
           L+NG  IP IG+GT+K    +   A+K A++ GYR I  AFVY NE+ VG+A++    +G
Sbjct: 4   LNNGHSIPPIGLGTYKITGSDGVAAIKSAVEFGYRLIDTAFVYNNEQVVGQALREIFSQG 63

Query: 316 -VVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPT 492
             + RED+FI SKL  TFHRP+ V     +SL  L +DY+DLYL+H P A ++       
Sbjct: 64  NDINREDVFIVSKLGPTFHRPEAVEKGCRLSLERLGLDYVDLYLMHTPVAARDSG----- 118

Query: 493 DADGKIQFSD-VDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPGH*PGR 669
           D + + +  D V  ++TWKALE     GLVRS+GVSNFN +QL  I+ + S++P      
Sbjct: 119 DGNDRSEIDDEVTPLETWKALEECQRKGLVRSIGVSNFNEEQLMEIVTHGSIRPVVNQVE 178

Query: 670 MPSVFKPXAIEAVLRRP*YYDNGVLPRWGXPDRPWAKPGDPHL-MEDPKLKEIADRLGKX 846
               F    +     R    +  ++  +    +P  KPG  H+ ++   L ++A++ G+ 
Sbjct: 179 CSIGFHQVKLRKFCNR----EGILIMAYSPLGKP--KPGKKHVFLDSSDLNKMAEKYGRS 232

Query: 847 AAQ 855
            AQ
Sbjct: 233 PAQ 235



 Score = 34.7 bits (76), Expect = 6.8
 Identities = 15/34 (44%), Positives = 20/34 (58%)
 Frame = +2

Query: 653 VTNQVECHPYLNXKRLKQFCEDRDIMITXYSPXG 754
           V NQVEC    +  +L++FC    I+I  YSP G
Sbjct: 173 VVNQVECSIGFHQVKLRKFCNREGILIMAYSPLG 206


>UniRef50_A7CWF9 Cluster: Aldehyde reductase; n=2; Bacteria|Rep:
           Aldehyde reductase - Opitutaceae bacterium TAV2
          Length = 347

 Score =  151 bits (367), Expect = 4e-35
 Identities = 94/251 (37%), Positives = 133/251 (52%), Gaps = 7/251 (2%)
 Frame = +1

Query: 121 VPVTTLSNGAKIPVIGIGTWKSK---PGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEA 291
           +P  TL++GA++P IG+GT+ S    PGEV  +V  A ++GYRH  CA VY NE+E+G  
Sbjct: 16  IPQRTLASGARMPAIGMGTFGSDHAAPGEVAASVYAAAELGYRHFDCAAVYSNEREIGAT 75

Query: 292 IKTKIQEGV-VKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWP-QAY 465
            +  +     ++REDL+ITSKLWN  H    V  A E SLR+L +DYLDLYLIHWP   +
Sbjct: 76  FRRILTSNTGIRREDLWITSKLWNDKHAEADVIPAFEKSLRDLGLDYLDLYLIHWPFPNF 135

Query: 466 KEDDAIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASV 645
                   + +     +   +++ TW+ LE L   GLVR +G SN    +LQ +L +A V
Sbjct: 136 HPPGCDVSSRSPDARPYIHAEFMKTWRQLETLHDRGLVRHIGTSNMTIAKLQLLLRDARV 195

Query: 646 KPGH*PGRMPSVFKPXAIEAVLRRP*YYDNGVLPRWGXPDRPW--AKPGDPHLMEDPKLK 819
           +P      +   F+  A+   +R       G  P  G P RP       D   +EDP ++
Sbjct: 196 RPAVNEMELHPHFQQPALFDYVRVRNIVPVGYCP-LGSPGRPERDRTAEDTSPLEDPVIQ 254

Query: 820 EIADRLGKXAA 852
            IA   G   A
Sbjct: 255 RIAAAHGMHPA 265


>UniRef50_P26690 Cluster: NAD(P)H-dependent 6'-deoxychalcone
           synthase; n=3; Papilionoideae|Rep: NAD(P)H-dependent
           6'-deoxychalcone synthase - Glycine max (Soybean)
          Length = 315

 Score =  151 bits (367), Expect = 4e-35
 Identities = 86/237 (36%), Positives = 135/237 (56%), Gaps = 2/237 (0%)
 Frame = +1

Query: 151 KIPVIGIGTWK--SKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQEGVVK 324
           ++PV+G+G+    +   +  +A+ +A+  GYRH   A  YG+E+ +GEA+K  I  G+V 
Sbjct: 20  RMPVVGMGSAPDFTCKKDTKEAIIEAVKQGYRHFDTAAAYGSEQALGEALKEAIHLGLVS 79

Query: 325 REDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTDADG 504
           R+DLF+TSKLW T + P LV  AL  SL+ L ++YLDLYLIHWP + +     FP + + 
Sbjct: 80  RQDLFVTSKLWVTENHPHLVLPALRKSLKTLQLEYLDLYLIHWPLSSQPGKFSFPIEVED 139

Query: 505 KIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPGH*PGRMPSVF 684
            + F   D    W+++E     GL +++GVSNF+ K+LQ +L  A+++P      M   +
Sbjct: 140 LLPF---DVKGVWESMEECQKLGLTKAIGVSNFSVKKLQNLLSVATIRPVVDQVEMNLAW 196

Query: 685 KPXAIEAVLRRP*YYDNGVLPRWGXPDRPWAKPGDPHLMEDPKLKEIADRLGKXAAQ 855
           +   +    +     +NG++     P R  A  G   +ME+  LKEIA+  GK  AQ
Sbjct: 197 QQKKLREFCK-----ENGIIVTAFSPLRKGASRGPNEVMENDVLKEIAEAHGKSIAQ 248


>UniRef50_UPI00015B4B22 Cluster: PREDICTED: similar to GA15457-PA;
           n=1; Nasonia vitripennis|Rep: PREDICTED: similar to
           GA15457-PA - Nasonia vitripennis
          Length = 388

 Score =  151 bits (365), Expect = 7e-35
 Identities = 78/175 (44%), Positives = 110/175 (62%), Gaps = 1/175 (0%)
 Frame = +1

Query: 136 LSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQEG 315
           LS+G +IP +G+GT   K  E+  A+  A++ GYRHI  AF Y NE  +G+ +K    +G
Sbjct: 28  LSSGHEIPAVGLGTSTIKLDEMDNAISSALENGYRHIDTAFSYDNEAAIGKILKKWFDKG 87

Query: 316 VVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAI-FPT 492
             KRED+FITSKL +  +RP  V   L+ SL++L +DY+D+YLIH P A KE + +    
Sbjct: 88  G-KREDIFITSKLPSQGNRPQSVETYLKRSLKDLGLDYVDMYLIHTPFAVKEGENLSSKQ 146

Query: 493 DADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPGH 657
           D DG   F DVD+   WKA+E  V  G  +S+G+SNFN  Q+  I +NA +KP +
Sbjct: 147 DKDGNDLFDDVDHKALWKAMERQVKEGRAKSIGLSNFNQSQVLNIYNNAEIKPSN 201



 Score = 41.1 bits (92), Expect = 0.079
 Identities = 15/31 (48%), Positives = 24/31 (77%)
 Frame = +2

Query: 662 QVECHPYLNXKRLKQFCEDRDIMITXYSPXG 754
           QVE H YL  K+L++FC++ +I++T Y+P G
Sbjct: 203 QVETHAYLQQKQLRKFCKEHNIVMTAYAPLG 233


>UniRef50_A2EHN6 Cluster: Oxidoreductase, aldo/keto reductase family
           protein; n=10; Trichomonas vaginalis|Rep:
           Oxidoreductase, aldo/keto reductase family protein -
           Trichomonas vaginalis G3
          Length = 312

 Score =  150 bits (363), Expect = 1e-34
 Identities = 91/243 (37%), Positives = 132/243 (54%), Gaps = 8/243 (3%)
 Frame = +1

Query: 151 KIPVIGIGTWKSK-PGEVTQAVKDAID-IGYRHIXCAFVYGNEKEVGEAIKTKIQEGVVK 324
           +IP +G GT+ +  P ++  A+  AI+  G RHI  AF Y N+  +GE +K    +G +K
Sbjct: 2   EIPQLGFGTYLANDPAKLKAALHYAIEECGVRHIDTAFAYYNQNVIGETLKEIFAKGKIK 61

Query: 325 REDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYK----EDDAIFPT 492
           RED+FIT+KLW T HR DLV   L  +L  L + Y+DL+LIH P A+K    +D  + P 
Sbjct: 62  REDMFITTKLWCTHHRKDLVEPELHENLAQLQLSYVDLFLIHQPIAFKSLPAKDGTMMPK 121

Query: 493 DADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKP--GH*PG 666
           D  GKIQ+  +D ++T+ A+E     GL R +GVSNF+ +QL+RI  N  +KP       
Sbjct: 122 DEKGKIQYEQIDILETYHAMEECQKKGLTRHIGVSNFSIEQLERIWFNCEIKPYANQVEC 181

Query: 667 RMPSVFKPXAIEAVLRRP*YYDNGVLPRWGXPDRPWAKPGDPHLMEDPKLKEIADRLGKX 846
            +   FKP              +  +   G P  P   P    L+EDP +K++A    K 
Sbjct: 182 NIYRQFKPLLSYCESHNIYLMAHTTI---GHP--PLKGPFGTSLLEDPVVKQVASEAKKT 236

Query: 847 AAQ 855
           +AQ
Sbjct: 237 SAQ 239


>UniRef50_A7PNI3 Cluster: Chromosome chr1 scaffold_22, whole genome
           shotgun sequence; n=2; Vitis vinifera|Rep: Chromosome
           chr1 scaffold_22, whole genome shotgun sequence - Vitis
           vinifera (Grape)
          Length = 360

 Score =  149 bits (362), Expect = 2e-34
 Identities = 77/173 (44%), Positives = 109/173 (63%), Gaps = 1/173 (0%)
 Frame = +1

Query: 136 LSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQEG 315
           L+  AKIP IG+GTW+S      +AVK A+  GYR I CA +YGNE EVGEA+  +   G
Sbjct: 14  LNTKAKIPAIGLGTWQSGGDLCVEAVKRALSEGYRQIDCAHLYGNEVEVGEAL-AEAFNG 72

Query: 316 VVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTD 495
            +KRED+F+TSKL+ T +  + +  ++ VSL+NL + YLDLYL+HWP      DA  P  
Sbjct: 73  SLKREDVFLTSKLYCTMNSLNKIENSVRVSLKNLGVTYLDLYLMHWPDITAFGDATDPPS 132

Query: 496 ADGKIQFSDVDYV-DTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKP 651
             G      ++ +   WKA+E L+  GLVR++GVSNF  +Q++ +L  A + P
Sbjct: 133 NSGNDHRQFLNRLKKAWKAMEGLIELGLVRAIGVSNFGVQQIKELLKFAKIVP 185



 Score = 35.9 bits (79), Expect = 3.0
 Identities = 14/41 (34%), Positives = 24/41 (58%)
 Frame = +2

Query: 659 NQVECHPYLNXKRLKQFCEDRDIMITXYSPXGXLPTDPGLS 781
           NQV+ HP+     L +FC+ + I ++ ++P G   + PG S
Sbjct: 188 NQVKLHPFWRQDELVKFCQSKGIHVSAHTPLGVPASGPGPS 228


>UniRef50_Q17G72 Cluster: Aldo-keto reductase; n=9;
           Endopterygota|Rep: Aldo-keto reductase - Aedes aegypti
           (Yellowfever mosquito)
          Length = 316

 Score =  149 bits (361), Expect = 2e-34
 Identities = 86/242 (35%), Positives = 130/242 (53%), Gaps = 1/242 (0%)
 Frame = +1

Query: 133 TLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQE 312
           T  NG  +P +G GTW++   EV +A+ +A++ GYRHI  A VY NEK +G+ +K  +  
Sbjct: 8   TFENGTTMPALGFGTWRASDEEVEKALNEALEAGYRHIDTAPVYLNEKTIGKVLKEWMDA 67

Query: 313 GVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPT 492
           G V R++LFI +KL     R   V   L+ SL +L ++Y+DLY +H P    E D  F  
Sbjct: 68  GKVTRDELFIVTKLPPHGTRASTVEKFLKNSLDDLQLEYVDLYHVHVPFTVPEVDGPFLV 127

Query: 493 DADGKIQF-SDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPGH*PGR 669
           + DG I   +  D+V  WKA+E +   GL R++G+SNFN +Q+QRILDN  +KP +    
Sbjct: 128 E-DGLIVLETTTDHVALWKAMEEVYEAGLARNIGLSNFNQRQIQRILDNCQIKPANLQIE 186

Query: 670 MPSVFKPXAIEAVLRRP*YYDNGVLPRWGXPDRPWAKPGDPHLMEDPKLKEIADRLGKXA 849
                +   +    +          P              P L+++P +K+IA++LGK  
Sbjct: 187 NHIYLQQPELVKFCKANGITVTAYSPLGSKGIEKLLGREVPDLLDNPVVKDIAEKLGKSP 246

Query: 850 AQ 855
           AQ
Sbjct: 247 AQ 248


>UniRef50_Q6RZX1 Cluster: Gld1; n=22; Pezizomycotina|Rep: Gld1 -
           Trichoderma atroviride (Hypocrea atroviridis)
          Length = 327

 Score =  149 bits (360), Expect = 3e-34
 Identities = 90/251 (35%), Positives = 138/251 (54%), Gaps = 10/251 (3%)
 Frame = +1

Query: 133 TLSNGAKIPVIGIGTWKSK--PGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKI 306
           TL+ GAKIP +G GT+ ++   GE   AV  A+D+GYRH+ CA+ Y NE EVG+AI+  +
Sbjct: 16  TLNTGAKIPAVGFGTFANEGAKGETYAAVTKALDVGYRHLDCAWFYLNEDEVGDAIRDFL 75

Query: 307 -QEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWP-QAYKEDDA 480
            +   V R+DLFI +K+WN  H P+ V+ + + S  NL +DY+DL+L+HWP  A K  D 
Sbjct: 76  ARRPDVTRKDLFICTKVWNHLHEPEDVKWSAKNSCENLKVDYIDLFLVHWPIAAEKNADR 135

Query: 481 IFPTDADGKIQFSDV---DYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKP 651
                 DGK   +     +   TW+A+E LV  G+V+++GVSN+    L+++L+ A +KP
Sbjct: 136 TVKIGPDGKYVINKALTENPEPTWRAMEELVDSGIVKAIGVSNWTIPGLKQLLEFARIKP 195

Query: 652 GH*PGRM-PSVFKPXAIEAVLRRP*YYDNGVLPRWGXP--DRPWAKPGDPHLMEDPKLKE 822
                 + P +     +E        + N +LP    P   +         + ++P L  
Sbjct: 196 AVNQIEIHPFLPNTELVEFC------FQNDILPEAYSPLGSQNQVPTTGERVRDNPTLNA 249

Query: 823 IADRLGKXAAQ 855
           +ADR G   AQ
Sbjct: 250 VADRRGSSLAQ 260



 Score = 37.1 bits (82), Expect = 1.3
 Identities = 15/32 (46%), Positives = 19/32 (59%)
 Frame = +2

Query: 659 NQVECHPYLNXKRLKQFCEDRDIMITXYSPXG 754
           NQ+E HP+L    L +FC   DI+   YSP G
Sbjct: 198 NQIEIHPFLPNTELVEFCFQNDILPEAYSPLG 229


>UniRef50_UPI000023D0F1 Cluster: hypothetical protein FG03517.1;
           n=1; Gibberella zeae PH-1|Rep: hypothetical protein
           FG03517.1 - Gibberella zeae PH-1
          Length = 364

 Score =  148 bits (359), Expect = 3e-34
 Identities = 76/166 (45%), Positives = 106/166 (63%)
 Frame = +1

Query: 154 IPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQEGVVKRED 333
           IP  G+GTW +  G V  AV+ A+  GYRHI  A ++ NE EVG+ IK       V R++
Sbjct: 60  IPAFGLGTWLAGKGVVVPAVEYALKGGYRHIDTALIWRNEDEVGKGIKAS----GVSRDE 115

Query: 334 LFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTDADGKIQ 513
           +++T KLWNT HRP+LVR A+E S+ NL ++YLDLYLIH+P A+  +      D D    
Sbjct: 116 IWVTGKLWNTDHRPELVRKAIETSIANLGVEYLDLYLIHYPVAWVPE----TRDVD---- 167

Query: 514 FSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKP 651
            ++   +DTWKA+E LV  GL R++G SNF  K + +IL  AS++P
Sbjct: 168 -NNTSLIDTWKAMEELVRAGLTRNIGFSNFAPKDINKILKIASIQP 212


>UniRef50_Q0CLQ2 Cluster: Putative uncharacterized protein; n=1;
           Aspergillus terreus NIH2624|Rep: Putative
           uncharacterized protein - Aspergillus terreus (strain
           NIH 2624)
          Length = 301

 Score =  146 bits (354), Expect = 1e-33
 Identities = 97/263 (36%), Positives = 137/263 (52%), Gaps = 24/263 (9%)
 Frame = +1

Query: 136 LSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQEG 315
           LS+G  +P +G+GTW SKP EV  AV+ A+ +GYRHI  A  Y NE EVG   K    + 
Sbjct: 9   LSSGYDMPAVGLGTWLSKPHEVENAVETALRLGYRHIDAAACYLNENEVGNGWK----KS 64

Query: 316 VVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYL----------------- 444
            V R+ +FITSKLWNT H PD V  A+  +L++L  DYLDLYL                 
Sbjct: 65  GVPRDQIFITSKLWNTHHHPDHVEEAVNKTLKDLQTDYLDLYLVFPSLLVLIHDLLSLLT 124

Query: 445 ---IHWPQAYKE-DDAIFPTDADGK-IQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNS 609
              IHWP A++  ++ + P D   K  + +++   DTW ALE LV  G VRS+GVSNF  
Sbjct: 125 NNKIHWPVAFEHTNETLTPIDPVSKRFRLANIPIADTWAALEKLVDAGKVRSIGVSNFTI 184

Query: 610 KQLQRILDNASVKPGH*PGRMPSVFKPXAIEAVLRRP*YYDNGVLPRWGXPDRPWAKP-- 783
           ++++ +L  A + P     ++ +   P   +  L +  Y    V         P      
Sbjct: 185 EKIEELLKTARIPPA--VNQIEA--HPYLQQPALHK--YLKEKVTNILSVAYSPLGNNIY 238

Query: 784 GDPHLMEDPKLKEIADRLGKXAA 852
             P +++DP +KEIA +L K  A
Sbjct: 239 NAPRVVDDPTVKEIAQKLNKDPA 261


>UniRef50_Q1YPE5 Cluster: Aldehyde reductase; n=7; Bacteria|Rep:
           Aldehyde reductase - gamma proteobacterium HTCC2207
          Length = 330

 Score =  146 bits (353), Expect = 2e-33
 Identities = 75/186 (40%), Positives = 113/186 (60%), Gaps = 9/186 (4%)
 Frame = +1

Query: 121 VPVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKT 300
           VP   +S+ + +P +G+G WK       QAV +AI +GYRH+  A  YGNE++VGE I  
Sbjct: 7   VPGVKVSSKS-MPAVGLGLWKITQDSAAQAVYEAIKVGYRHLDSAADYGNEQQVGEGIAR 65

Query: 301 KIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQA--YKED 474
            I EG+  RE+L+IT+KLWNT+HR + V  A   S+ +L +DY+DLYL+H+P A  Y + 
Sbjct: 66  AIAEGLCSREELWITTKLWNTYHRAEHVEAACRRSMDDLGLDYIDLYLVHFPIALRYVDF 125

Query: 475 DAIFPTD-------ADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILD 633
           +  +P +        D  ++   V   +TW A+E LV  GLVR +GV N+++  L  ++ 
Sbjct: 126 NDRYPAEWIFDHSAEDPAMELDQVPLSETWGAMEQLVESGLVRQIGVCNYSAVLLHDLMS 185

Query: 634 NASVKP 651
            A +KP
Sbjct: 186 YARIKP 191


>UniRef50_Q6CFG7 Cluster: Yarrowia lipolytica chromosome B of strain
           CLIB122 of Yarrowia lipolytica; n=9; Ascomycota|Rep:
           Yarrowia lipolytica chromosome B of strain CLIB122 of
           Yarrowia lipolytica - Yarrowia lipolytica (Candida
           lipolytica)
          Length = 337

 Score =  146 bits (353), Expect = 2e-33
 Identities = 81/184 (44%), Positives = 112/184 (60%), Gaps = 4/184 (2%)
 Frame = +1

Query: 112 MTSVPVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAI-DIGYRHIXCAFVYGNEKEVGE 288
           MTS+  T L+NG  IP IG+GTWKS   EV  AV+ A+ + GYRHI  AF Y NE  VG 
Sbjct: 29  MTSLDFT-LNNGKTIPAIGLGTWKSTTEEVAGAVECALTEGGYRHIDTAFNYRNEDAVGL 87

Query: 289 AIKTKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYK 468
            IK  +++G VKRED+F+T+K+W T+H  D V   L++SL  L +DY+D+ LIHWP    
Sbjct: 88  GIKRAMEKG-VKREDIFVTTKIWVTYH--DRVEENLDMSLERLGLDYVDMLLIHWPVPLN 144

Query: 469 E--DDAIFPTDADGKIQFSDV-DYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNA 639
              +D ++P   DG     +      TWK +E ++  G  +S+GVSNF+   L+ +L  A
Sbjct: 145 PNGNDPVYPLRPDGSRDIDESGSQPKTWKQMEAVLKTGKTKSIGVSNFSIPYLEELLKEA 204

Query: 640 SVKP 651
            V P
Sbjct: 205 EVVP 208



 Score = 37.1 bits (82), Expect = 1.3
 Identities = 15/32 (46%), Positives = 21/32 (65%)
 Frame = +2

Query: 659 NQVECHPYLNXKRLKQFCEDRDIMITXYSPXG 754
           NQVE HP L    L +FC+  +I++T +SP G
Sbjct: 211 NQVELHPLLPQLELMEFCKKNNIVMTAFSPFG 242


>UniRef50_UPI00015B40FA Cluster: PREDICTED: similar to CG2767-PA;
           n=2; Nasonia vitripennis|Rep: PREDICTED: similar to
           CG2767-PA - Nasonia vitripennis
          Length = 356

 Score =  145 bits (352), Expect = 2e-33
 Identities = 75/187 (40%), Positives = 115/187 (61%), Gaps = 3/187 (1%)
 Frame = +1

Query: 106 LIMTSVPVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVG 285
           +I +      LS+G  +P+IG+GTW+  P  +  AV  A++ GYRHI  AF YGNE+ +G
Sbjct: 20  VITSGYKTIKLSSGHDMPMIGLGTWQMPPEAIEVAVTAALESGYRHIDTAFTYGNEEAIG 79

Query: 286 EAIKTKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAY 465
           + +K    +G  KREDLFIT+KL     R + V   L++SL  L ++Y+++YLIH P A+
Sbjct: 80  KTLKKWFDKG-GKREDLFITTKLPPIGMRAEYVESYLKLSLEKLGLEYVNMYLIHKPFAF 138

Query: 466 KEDDAIF--PTDADGKIQF-SDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDN 636
            +D   +    + DG +   +D D+V  W+A+E  V  G VRS+G+SNFN  QL  + ++
Sbjct: 139 VKDKYKYEPALNPDGSVVLDTDTDHVAIWRAMEKQVKAGRVRSIGLSNFNKSQLLNVYEH 198

Query: 637 ASVKPGH 657
           A +KP +
Sbjct: 199 AEIKPSN 205


>UniRef50_Q6C2L0 Cluster: Yarrowia lipolytica chromosome F of strain
           CLIB122 of Yarrowia lipolytica; n=3; Yarrowia
           lipolytica|Rep: Yarrowia lipolytica chromosome F of
           strain CLIB122 of Yarrowia lipolytica - Yarrowia
           lipolytica (Candida lipolytica)
          Length = 324

 Score =  145 bits (351), Expect = 3e-33
 Identities = 74/178 (41%), Positives = 115/178 (64%), Gaps = 6/178 (3%)
 Frame = +1

Query: 136 LSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQEG 315
           L++G  IP +G+GT  +  G V + V  AI  GYRHI  AF+YG+E +VG+ IK  I E 
Sbjct: 9   LNDGHSIPALGLGT--ASDGNVEEVVYAAIKNGYRHIDTAFIYGSEVDVGKGIKRAIDEE 66

Query: 316 VVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDD----AI 483
           +VKRE+LF+T+K+W TF+  + V  +L++SL++L++DY+DL L+HWP +   D     AI
Sbjct: 67  LVKRENLFVTTKVWPTFY--NRVSESLDISLKDLSLDYVDLLLVHWPVSLLADSDDPRAI 124

Query: 484 FPTDADGKIQFSDV--DYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKP 651
           +  + DG +++SD   D++ T+K +E     G  +S+GVSN +   L+R+LD     P
Sbjct: 125 YLVNTDGSVRYSDSLDDWITTYKQIEEEKLSGRTKSIGVSNVSEVYLKRLLDQVKTVP 182



 Score = 35.5 bits (78), Expect = 3.9
 Identities = 15/32 (46%), Positives = 20/32 (62%)
 Frame = +2

Query: 659 NQVECHPYLNXKRLKQFCEDRDIMITXYSPXG 754
           NQ E HPYL  K+  +F E   I++T +SP G
Sbjct: 185 NQFEIHPYLPQKKEIEFNEKHGILVTAFSPLG 216


>UniRef50_Q03PG5 Cluster: Aldo/keto reductase of diketogulonate
           reductase family; n=1; Lactobacillus brevis ATCC
           367|Rep: Aldo/keto reductase of diketogulonate reductase
           family - Lactobacillus brevis (strain ATCC 367 / JCM
           1170)
          Length = 268

 Score =  144 bits (350), Expect = 4e-33
 Identities = 94/244 (38%), Positives = 135/244 (55%), Gaps = 2/244 (0%)
 Frame = +1

Query: 130 TTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQ 309
           T LSNG  IP++G GT+     +V  A+K A+D GYRH+ CA +YGNE  VGEAIK    
Sbjct: 4   TQLSNGVTIPMLGFGTYLIDSKDVPAAIKTALDAGYRHLDCAHIYGNEPAVGEAIKA--- 60

Query: 310 EGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFP 489
              + R DLFITSK+WN     D    A + +L +L +DYLDLYLIHWP    EDD    
Sbjct: 61  -SGIDRSDLFITSKVWNADQGYDKTLAAFDQTLSDLQLDYLDLYLIHWP---NEDDFELT 116

Query: 490 TDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPGH*PGR 669
                         +DTW+ LE L     VR++GVSNF+  QL+++ + A+VKP      
Sbjct: 117 --------------LDTWRVLETLYQQKKVRAIGVSNFSEDQLKQVFEMATVKP-----M 157

Query: 670 MPSVFK-PXAIEAVLRRP*YYDNGVLPRWGXPDRPWAKPGDPHL-MEDPKLKEIADRLGK 843
           +  + + P  ++A L +    DN ++      +  ++  G  HL +EDP + ++A++ GK
Sbjct: 158 INQIERHPYKVQADLGQ-FDTDNDIV------NEGYSPIGHGHLILEDPVITKLAEKYGK 210

Query: 844 XAAQ 855
             AQ
Sbjct: 211 SPAQ 214


>UniRef50_Q1U9L6 Cluster: 2,5-didehydrogluconate reductase; n=3;
           Lactobacillus|Rep: 2,5-didehydrogluconate reductase -
           Lactobacillus reuteri 100-23
          Length = 288

 Score =  144 bits (349), Expect = 6e-33
 Identities = 81/183 (44%), Positives = 111/183 (60%), Gaps = 1/183 (0%)
 Frame = +1

Query: 106 LIMTSVPVT-TLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEV 282
           L +T++  T  L+NG KIP +G GT+++      QAVK+AI+ GYRHI  A VYGNE+ V
Sbjct: 2   LELTNINSTFNLNNGVKIPCVGYGTFRTPADVAEQAVKEAIETGYRHIDTAAVYGNEEAV 61

Query: 283 GEAIKTKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQA 462
           G+ IK    +  +KREDLF+TSKLWNT    +  + A + +L  L +DYLDLYLIHWP  
Sbjct: 62  GKGIK----DSGIKREDLFVTSKLWNTNRGYEQTKKAFQETLDRLQMDYLDLYLIHWPAN 117

Query: 463 YKEDDAIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNAS 642
            K+    F  DA  KI        +TW+A+E L   G +R++GVSNF    +  ++  A 
Sbjct: 118 EKQ----FGDDA-AKIN------AETWRAMEDLYNEGKIRAIGVSNFMPHHIAELMKTAK 166

Query: 643 VKP 651
           V P
Sbjct: 167 VAP 169


>UniRef50_A1D4E3 Cluster: D-xylose reductase (Xyl1), putative; n=5;
           Pezizomycotina|Rep: D-xylose reductase (Xyl1), putative
           - Neosartorya fischeri (strain ATCC 1020 / DSM 3700 /
           NRRL 181)(Aspergillus fischerianus (strain ATCC 1020 /
           DSM 3700 / NRRL 181))
          Length = 321

 Score =  144 bits (349), Expect = 6e-33
 Identities = 75/183 (40%), Positives = 107/183 (58%), Gaps = 5/183 (2%)
 Frame = +1

Query: 118 SVPVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIK 297
           + P T L++G  +P++G G WK         +  AI  GYR    A  YGNE E G+ + 
Sbjct: 2   TTPSTKLNSGYDMPLVGFGLWKVNNETCADQIYHAIKAGYRLFDGACDYGNEVEAGKGVA 61

Query: 298 TKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYK-ED 474
             IQEG+VKREDLFI SKLWN+FH  D V       L +  +DY DL+++H+P A K  D
Sbjct: 62  RAIQEGIVKREDLFIVSKLWNSFHDGDRVEPICRKQLADWGLDYFDLFIVHFPIALKYVD 121

Query: 475 DAI-FP---TDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNAS 642
            A+ +P      + K++FS+    +TW A+E LV   L RS+GVSNF+++ L  +L  A 
Sbjct: 122 PAVRYPPGWLSENNKLEFSNASIQETWTAMESLVDKKLARSIGVSNFSAQLLMDLLRYAR 181

Query: 643 VKP 651
           ++P
Sbjct: 182 IRP 184



 Score = 34.3 bits (75), Expect = 9.0
 Identities = 15/35 (42%), Positives = 20/35 (57%)
 Frame = +2

Query: 656 TNQVECHPYLNXKRLKQFCEDRDIMITXYSPXGXL 760
           T Q+E HPYL  +RL  + +   I +T YS  G L
Sbjct: 186 TLQIEHHPYLTQERLVTYAQKEGIAVTAYSSFGPL 220


>UniRef50_P28475 Cluster: NADP-dependent D-sorbitol-6-phosphate
           dehydrogenase; n=71; Magnoliophyta|Rep: NADP-dependent
           D-sorbitol-6-phosphate dehydrogenase - Malus domestica
           (Apple) (Malus sylvestris)
          Length = 310

 Score =  142 bits (345), Expect = 2e-32
 Identities = 89/249 (35%), Positives = 133/249 (53%), Gaps = 8/249 (3%)
 Frame = +1

Query: 133 TLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQE 312
           TLS+G ++PVIG+G W+ +  E+ + + +AI IGYRH  CA  Y +E +VGEA+    + 
Sbjct: 5   TLSSGYEMPVIGLGLWRLEKDELKEVILNAIKIGYRHFDCAAHYKSEADVGEALAEAFKT 64

Query: 313 GVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPT 492
           G+VKRE+LFIT+K+WN+ H    V  A + SL  L IDYLDLYL+H+P   K +      
Sbjct: 65  GLVKREELFITTKIWNSDH--GHVVEACKNSLEKLQIDYLDLYLVHYPMPTKHNAIGKTA 122

Query: 493 DADGKIQFSDVDYV----DTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPGH* 660
              G+ +  D+D       TW+ +E  V  GLVRS+G+SN+     +  L  + +KP   
Sbjct: 123 SLLGEDKVLDIDVTISLQQTWEGMEKTVSLGLVRSIGLSNYELFLTRDCLAYSKIKPAVS 182

Query: 661 PGRMPSVFKPXAIEAVLRRP*YYDNGVLPRWGXPDRPWAKP----GDPHLMEDPKLKEIA 828
                  F+  ++     +     +GVLP    P    A      G    ++DP L ++A
Sbjct: 183 QFETHPYFQRDSLVKFCMK-----HGVLPTAHTPLGGAAANKDMFGSVSPLDDPVLNDVA 237

Query: 829 DRLGKXAAQ 855
            + GK  AQ
Sbjct: 238 KKYGKSVAQ 246


>UniRef50_Q6TY50 Cluster: Reductase 2; n=10; Magnoliophyta|Rep:
           Reductase 2 - Hydrangea macrophylla (Bigleaf hydrangea)
          Length = 321

 Score =  142 bits (344), Expect = 2e-32
 Identities = 74/183 (40%), Positives = 116/183 (63%), Gaps = 5/183 (2%)
 Frame = +1

Query: 118 SVPVTTLSNGA-KIPVIGIGTWKSKPGE---VTQAVKDAIDIGYRHIXCAFVYGNEKEVG 285
           ++P   LS+G  K+PV+G+GT    P +   V +AV +A+ +GYRH   A +Y +E+ +G
Sbjct: 4   TIPEVPLSSGGRKMPVLGLGTAADPPVDPETVRKAVTEALKLGYRHFDTAALYNSEQPLG 63

Query: 286 EAIKTKIQEGVVK-REDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQA 462
           +AI   + EG++K R++LFITSKLW +    + V  AL+ +L+NL ++Y+D+YLIHWP +
Sbjct: 64  DAIAEALGEGLIKSRDELFITSKLWCSDAHRENVEPALQKTLKNLKLEYIDMYLIHWPVS 123

Query: 463 YKEDDAIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNAS 642
            K  +  +P     K  F  +DY   W+A+E     GL +++GVSNF+ K+L  +L NA 
Sbjct: 124 SKPGNYEYPIK---KEDFLQMDYKSVWEAMEECQKLGLTKAIGVSNFSCKKLSDVLANAK 180

Query: 643 VKP 651
           V P
Sbjct: 181 VPP 183


>UniRef50_Q5FK98 Cluster: Oxidoreductase; n=8; Lactobacillales|Rep:
           Oxidoreductase - Lactobacillus acidophilus
          Length = 285

 Score =  141 bits (342), Expect = 4e-32
 Identities = 72/174 (41%), Positives = 108/174 (62%), Gaps = 1/174 (0%)
 Frame = +1

Query: 133 TLSNGAKIPVIGIGTWKSKPGEVTQ-AVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQ 309
           TL+NG KIP+IG GTW++  GEV + +V  A++ GYRHI  A  YGNE  VG AI    Q
Sbjct: 11  TLNNGVKIPIIGFGTWQTPDGEVAEESVLAALNCGYRHIDTASAYGNEDSVGRAI----Q 66

Query: 310 EGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFP 489
           +  + R +LFIT+KLWN+ H  +  + A++ SL +L +DYLD+YLIHWP      D    
Sbjct: 67  KSGINRHELFITTKLWNSDHGYEKTKKAIDQSLLDLKLDYLDMYLIHWPNPSSMRD---- 122

Query: 490 TDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKP 651
                   +++++  ++W+A+E  V  G +R++GVSNF    L  +++ A +KP
Sbjct: 123 -------HWAEIN-AESWRAMEEAVRAGKIRAIGVSNFRKHHLDALMETAEIKP 168


>UniRef50_Q5KI95 Cluster: Aldo-keto reductase, putative; n=14;
           Dikarya|Rep: Aldo-keto reductase, putative -
           Cryptococcus neoformans (Filobasidiella neoformans)
          Length = 353

 Score =  141 bits (342), Expect = 4e-32
 Identities = 76/187 (40%), Positives = 108/187 (57%), Gaps = 3/187 (1%)
 Frame = +1

Query: 100 SNLIMTSVPVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKE 279
           ++LIM++     L+ GA IP IG+GTW++K GEV QAV  A+  GYRHI  A  Y NE E
Sbjct: 29  NSLIMSAPTSFKLNTGASIPAIGLGTWQAKAGEVRQAVAHALKAGYRHIDGALCYQNEDE 88

Query: 280 VGEAIKTKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWP- 456
           VG  IK    +  V R ++F+TSK+W+++H  D V   L+ +L++L  DYLDLYLIHWP 
Sbjct: 89  VGLGIK----DSGVPRSEIFLTSKVWSSYH--DRVEECLDTTLKSLQTDYLDLYLIHWPV 142

Query: 457 -QAYKEDDAIFPTDADGKIQFS-DVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRIL 630
             A      +FP   DG      D D   TW  +E ++  G  +++G+SN     ++ I+
Sbjct: 143 RLAPNGTHPLFPVKPDGSRNLDWDWDQAKTWAQMEDVLKKGKAKAIGLSNAGIPIIEHII 202

Query: 631 DNASVKP 651
               V P
Sbjct: 203 KTGKVTP 209



 Score = 37.5 bits (83), Expect = 0.97
 Identities = 14/32 (43%), Positives = 21/32 (65%)
 Frame = +2

Query: 659 NQVECHPYLNXKRLKQFCEDRDIMITXYSPXG 754
           NQVE HPY     L ++C+++ I++  YSP G
Sbjct: 212 NQVELHPYCPQHALLKYCKEKGILLEAYSPLG 243


>UniRef50_P23901 Cluster: Aldose reductase; n=9; Poaceae|Rep: Aldose
           reductase - Hordeum vulgare (Barley)
          Length = 320

 Score =  141 bits (341), Expect = 5e-32
 Identities = 73/173 (42%), Positives = 109/173 (63%), Gaps = 1/173 (0%)
 Frame = +1

Query: 136 LSNGAKIPVIGIGTWKSKPGEVTQAVKDAI-DIGYRHIXCAFVYGNEKEVGEAIKTKIQE 312
           L +G  +P +G+GTW++   +   +V+ AI + GYRH+  A  YG EKEVG+ +K  ++ 
Sbjct: 18  LKSGHAMPAVGLGTWRAG-SDTAHSVRTAITEAGYRHVDTAAEYGVEKEVGKGLKAAMEA 76

Query: 313 GVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPT 492
           G+  R+DLF+TSK+W T   P+ VR ALE +L++L +DY+DLY IHWP   K D A  P 
Sbjct: 77  GI-DRKDLFVTSKIWCTNLAPERVRPALENTLKDLQLDYIDLYHIHWPFRLK-DGAHMPP 134

Query: 493 DADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKP 651
           +A   ++F   D    WK +E LV  GLV+ +GV N+   +L R+L +A + P
Sbjct: 135 EAGEVLEF---DMEGVWKEMENLVKDGLVKDIGVCNYTVTKLNRLLRSAKIPP 184


>UniRef50_Q23320 Cluster: Putative uncharacterized protein; n=4;
           Caenorhabditis|Rep: Putative uncharacterized protein -
           Caenorhabditis elegans
          Length = 320

 Score =  140 bits (339), Expect = 9e-32
 Identities = 72/173 (41%), Positives = 106/173 (61%)
 Frame = +1

Query: 115 TSVPVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAI 294
           + VP+ TLSNG  +P IG+GTW+    E    +++A+  GYRHI  A +Y NE ++G+A+
Sbjct: 3   SKVPIFTLSNGVLMPSIGLGTWQMTGEEGKTVIRNAVLAGYRHIDTATLYQNEHQIGDAL 62

Query: 295 KTKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKED 474
                EG++KRED+FIT+K +     PD+V  AL  SL+ L +DY+DLYL H P + K+ 
Sbjct: 63  AELFAEGILKREDIFITTKAFCHEVAPDVVEEALRNSLKRLRLDYVDLYLAHIPASTKD- 121

Query: 475 DAIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILD 633
                   DG  + SDV   D W+  E +   GL +++GVSNFN  Q+ RI++
Sbjct: 122 --------DGSFR-SDVKVEDIWRGFEKVYGLGLTKAIGVSNFNESQIVRIMN 165


>UniRef50_UPI0000499B0E Cluster: oxidoreductase, aldo/keto reductase
           family; n=1; Entamoeba histolytica HM-1:IMSS|Rep:
           oxidoreductase, aldo/keto reductase family - Entamoeba
           histolytica HM-1:IMSS
          Length = 307

 Score =  140 bits (338), Expect = 1e-31
 Identities = 87/241 (36%), Positives = 129/241 (53%), Gaps = 1/241 (0%)
 Frame = +1

Query: 136 LSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGE-AIKTKIQE 312
           L+NG  +P IG+GTW + PGEV +AV  A++ GYR I CA  Y NEKE+GE  I+  ++ 
Sbjct: 8   LNNGKFMPAIGLGTWLAAPGEVGKAVTLALENGYRLIDCARFYKNEKEIGEMGIEPFLKN 67

Query: 313 GVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPT 492
               RE+LF+TSKLW    +   +R +   S+++L   YLDLYLIHWP A K D +  P 
Sbjct: 68  H--PREELFVTSKLW--MDQVTRIRESCLESIQDLKCKYLDLYLIHWPIALKVDASNPPK 123

Query: 493 DADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPGH*PGRM 672
             D    F D+D  + W+ +E LV  GLV+S+G+SNF   Q+++I+    +KP      +
Sbjct: 124 PED----FLDMDITEIWQEMERLVDEGLVKSIGLSNFTIPQIEKIMKMCRIKPVINQVEL 179

Query: 673 PSVFKPXAIEAVLRRP*YYDNGVLPRWGXPDRPWAKPGDPHLMEDPKLKEIADRLGKXAA 852
               +   +  V +          P  G P    A   D + ++D  +  +A +  K  A
Sbjct: 180 NVYLQQNKLREVCKSYNIVVEAYRPIGGKP----ANESDKNCLDDEVVVSLAKKYNKTTA 235

Query: 853 Q 855
           Q
Sbjct: 236 Q 236


>UniRef50_A6W8E7 Cluster: 2,5-didehydrogluconate reductase; n=3;
           Actinomycetales|Rep: 2,5-didehydrogluconate reductase -
           Kineococcus radiotolerans SRS30216
          Length = 289

 Score =  140 bits (338), Expect = 1e-31
 Identities = 92/246 (37%), Positives = 128/246 (52%)
 Frame = +1

Query: 118 SVPVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIK 297
           +VP   L++G +IP +G G ++ +PG+  QAVK A+D+GYRHI  A +YGNE EV +   
Sbjct: 11  TVPTILLNDGREIPQLGFGVFQIEPGDTAQAVKTALDLGYRHIDTAQMYGNEAEVAQG-- 68

Query: 298 TKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDD 477
             I +  V R+++++TSKL N FH PD  R A++ S+  L    +DLYLIHWP       
Sbjct: 69  --IADSGVPRDEIWVTSKLNNGFHEPDAARKAVDDSVEKLR-GPIDLYLIHWP------- 118

Query: 478 AIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPGH 657
              PT   G       D+V TWK LE     G +RS+GVSNF    LQR+   A+V P  
Sbjct: 119 --LPTLYGG-------DFVSTWKVLEEARAAGKLRSIGVSNFQVNHLQRLAQEATVVPA- 168

Query: 658 *PGRMPSVFKPXAIEAVLRRP*YYDNGVLPRWGXPDRPWAKPGDPHLMEDPKLKEIADRL 837
                  V      E V R    +  GV          W+      +++DP +  +A+RL
Sbjct: 169 --VNQIEVHPYFGNEEVRRHCGEHQIGV--------EAWSPIAQGKVLDDPTVTAVANRL 218

Query: 838 GKXAAQ 855
           GK  AQ
Sbjct: 219 GKSPAQ 224


>UniRef50_Q9FJK0 Cluster: Aldose reductase-like protein; n=3; core
           eudicotyledons|Rep: Aldose reductase-like protein -
           Arabidopsis thaliana (Mouse-ear cress)
          Length = 316

 Score =  140 bits (338), Expect = 1e-31
 Identities = 89/245 (36%), Positives = 132/245 (53%), Gaps = 2/245 (0%)
 Frame = +1

Query: 127 VTTLSNGAKIPVIGIGTW-KSKPGEVT-QAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKT 300
           V  L  G  IP++G+GT+   K  E T  AV  AI IGYRH   A +YG+E+ +G A+  
Sbjct: 5   VARLRCGETIPLLGMGTYCPQKDRESTISAVHQAIKIGYRHFDTAKIYGSEEALGTALGQ 64

Query: 301 KIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDA 480
            I  G V+R+DLF+TSKLW++ H   +   AL  +L+ + +DYLD YL+HWP   K    
Sbjct: 65  AISYGTVQRDDLFVTSKLWSSDHHDPI--SALIQTLKTMGLDYLDNYLVHWPIKLK-PGV 121

Query: 481 IFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPGH* 660
             P   + + +  D+   +TW+ +E  +  GL RS+GVSNF+SK++  +LD ASV P   
Sbjct: 122 SEPIPKEDEFE-KDLGIEETWQGMERCLEMGLCRSIGVSNFSSKKIFDLLDFASVSPSVN 180

Query: 661 PGRMPSVFKPXAIEAVLRRP*YYDNGVLPRWGXPDRPWAKPGDPHLMEDPKLKEIADRLG 840
              M  +++   +  V      + +G  P  G P   W   G   ++E P +K IA +  
Sbjct: 181 QVEMHPLWRQRKLRKVCEENNIHVSGYSP-LGGPGNCW---GSTAVIEHPIIKSIALKHN 236

Query: 841 KXAAQ 855
              AQ
Sbjct: 237 ATPAQ 241


>UniRef50_Q01J82 Cluster: OSIGBa0152K17.5 protein; n=28;
           Magnoliophyta|Rep: OSIGBa0152K17.5 protein - Oryza
           sativa (Rice)
          Length = 323

 Score =  139 bits (337), Expect = 2e-31
 Identities = 89/256 (34%), Positives = 133/256 (51%), Gaps = 8/256 (3%)
 Frame = +1

Query: 112 MTSVPVTTLSNGA--KIPVIGIGTWKS---KPGEVTQAVKDAIDIGYRHIXCAFVYGNEK 276
           M +VP   L +GA   +P +G+GT  S    P     A   A+++G+RH   A +YG E 
Sbjct: 1   MAAVPEVALRHGAGRPMPAVGVGTADSAATSPETKRGAALAALEVGFRHFDTAALYGTEA 60

Query: 277 EVGEAIKTKIQEGVV-KREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHW 453
            +GEAI    + G+V  RE++F+T+KLW T   P LV  +L  SLRNL ++Y+DLYL+HW
Sbjct: 61  PLGEAIAEATRRGLVASREEVFVTTKLWCTQCHPGLVLPSLRESLRNLQMEYVDLYLVHW 120

Query: 454 PQAYKEDDAIFPTDADGKIQFSDVDYVDTWKALEPLVCH--GLVRSLGVSNFNSKQLQRI 627
           P + K    + P   +  + F   D+   W+A+E   CH  GL +++GVSNF +K L ++
Sbjct: 121 PISVKPGPPMLPVKREDAVPF---DFEGVWRAMEE--CHRLGLAKAIGVSNFTTKHLDKL 175

Query: 628 LDNASVKPGH*PGRMPSVFKPXAIEAVLRRP*YYDNGVLPRWGXPDRPWAKPGDPHLMED 807
           L  A++ P      M  V++   +               P  G   + W   G+  +ME 
Sbjct: 176 LAVATIPPAVNQVEMNPVWQQRTVREYCAAKGIRVAAYSPLGG---QNWIGEGN-DVMES 231

Query: 808 PKLKEIADRLGKXAAQ 855
           P L +IA   GK  AQ
Sbjct: 232 PVLADIARARGKSIAQ 247


>UniRef50_Q41399 Cluster: Chalcone reductase; n=4;
           eudicotyledons|Rep: Chalcone reductase - Sesbania
           rostrata
          Length = 322

 Score =  138 bits (335), Expect = 3e-31
 Identities = 85/249 (34%), Positives = 136/249 (54%), Gaps = 4/249 (1%)
 Frame = +1

Query: 121 VPVTTLSNGAKIPVIGIGTW-KSKPGE--VTQAVKDAIDIGYRHIXCAFVYGNEKEVGEA 291
           +P   L++G K+PVIG+GT  +S+P    +     DAI +GYRH   A VYG E+ +G A
Sbjct: 6   IPEVLLNSGHKMPVIGMGTSVESRPSNDVLASIFVDAIQVGYRHFDSASVYGTEEAIGMA 65

Query: 292 IKTKIQEGVVK-REDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYK 468
           +   I++G++K R+++FITSK WNT    DL+  AL+ +L+ L ++Y+DLYLIHWP   +
Sbjct: 66  VSKAIEQGLIKSRDEVFITSKPWNTDAHHDLIVPALKTTLKKLGMEYVDLYLIHWPVRLR 125

Query: 469 EDDAIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVK 648
            D  +       K      D   TWKA+E     GL +S+G+ N+ +K+L ++L+ A++ 
Sbjct: 126 HD--LENPVIFSKEDLLPFDIEGTWKAMEECYRLGLAKSIGICNYGTKKLTKLLEIATIP 183

Query: 649 PGH*PGRMPSVFKPXAIEAVLRRP*YYDNGVLPRWGXPDRPWAKPGDPHLMEDPKLKEIA 828
           P      M   ++   +    ++   + +   P  G     W   G   +ME+  L++IA
Sbjct: 184 PAVNQVEMNPSWQQGNLREFCKQKGIHVSAWSP-LGAYKIFW---GSGAVMENQILQDIA 239

Query: 829 DRLGKXAAQ 855
              GK  AQ
Sbjct: 240 TAKGKTIAQ 248


>UniRef50_Q88SL1 Cluster: Oxidoreductase; n=51; Lactobacillales|Rep:
           Oxidoreductase - Lactobacillus plantarum
          Length = 286

 Score =  138 bits (334), Expect = 4e-31
 Identities = 76/174 (43%), Positives = 99/174 (56%), Gaps = 1/174 (0%)
 Frame = +1

Query: 133 TLSNGAKIPVIGIGTWKSKPGEVT-QAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQ 309
           TL+NG KIP++G GTW++  G+V   +V  A+  GYRHI  A  YGNE+ VG+AI     
Sbjct: 12  TLNNGTKIPIVGFGTWQTPDGQVAYDSVLAALKAGYRHIDTAAAYGNEESVGKAIA---- 67

Query: 310 EGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFP 489
           +  V REDLF+T+KLWN  H  D  + AL+ SL  L +DY+DLYLIHWP      D    
Sbjct: 68  DSGVAREDLFVTTKLWNADHGYDAAKKALDTSLAKLGLDYVDLYLIHWPNPAAMRDNWEQ 127

Query: 490 TDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKP 651
            +A            DTW+A+E        R++GVSNF  K L  +L  A V P
Sbjct: 128 LNA------------DTWRAMEEAYTARKARAIGVSNFRPKHLDALLKTAKVVP 169


>UniRef50_A6WDZ5 Cluster: Aldo/keto reductase; n=5; Bacteria|Rep:
           Aldo/keto reductase - Kineococcus radiotolerans SRS30216
          Length = 343

 Score =  138 bits (333), Expect = 5e-31
 Identities = 96/247 (38%), Positives = 125/247 (50%), Gaps = 7/247 (2%)
 Frame = +1

Query: 121 VPVTTLSNGAKIPVIGIGTWKS---KPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEA 291
           VP   L  GA +P IGIGT+ S    P EV  AV  A+  GYR + CA VYGNE +VGEA
Sbjct: 13  VPRRELRGGATVPAIGIGTFGSDRYSPAEVAAAVAGAVAAGYRLVDCAAVYGNEAQVGEA 72

Query: 292 IKTKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKE 471
           +   +  GV  R++LF+ SK+WN  H P     ++  SLR+L +D+LD   +HWP     
Sbjct: 73  LAGAVAGGV-DRDELFVVSKVWNDAHAPADAVASVHRSLRDLRLDHLDAVFVHWPFP-NH 130

Query: 472 DDAIFPTDA-DGKIQFSDVD-YVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASV 645
              +  TDA D + +  D D Y+  W ALE LV  GLVR LG SN    +L  +L +A +
Sbjct: 131 HPPMADTDARDPRARPYDHDAYLALWGALEGLVDSGLVRHLGTSNTTVAKLDLLLRDARI 190

Query: 646 KPGH*PGRMPSVFKPXAIEAVLRRP*YYDNGVLPRWGXPDRPW--AKPGDPHLMEDPKLK 819
            P      +   F+   + A   R      G  P  G P RP     PGD    EDP + 
Sbjct: 191 PPALNEMELHPCFQQPELFAHCVRHGIQPVGYSP-LGSPSRPERDRTPGDVVDTEDPVVV 249

Query: 820 EIADRLG 840
            IA   G
Sbjct: 250 RIAREHG 256


>UniRef50_Q4FY75 Cluster: Aldo-keto reductase-like protein; n=5;
           Trypanosomatidae|Rep: Aldo-keto reductase-like protein -
           Leishmania major strain Friedlin
          Length = 372

 Score =  138 bits (333), Expect = 5e-31
 Identities = 73/178 (41%), Positives = 99/178 (55%), Gaps = 8/178 (4%)
 Frame = +1

Query: 154 IPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQEGVVKRED 333
           IP +G GT++    E T AV  A+  GYRH+ CA  YGNE  VGEA+   ++    +RED
Sbjct: 30  IPQLGFGTYRLPVSEATDAVAFALSCGYRHVDCAKAYGNEAAVGEALAQALRTRCTRRED 89

Query: 334 LFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQA------YKEDDAIFPTD 495
           LF+TSKLW T   PD V  A   +L  L +DYLDLYLIHWP        +  D+  +P  
Sbjct: 90  LFVTSKLWPTDQHPDHVEAACRATLAALQLDYLDLYLIHWPVCMRHTPHWTSDEDRYPRH 149

Query: 496 ADGKIQF-SDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDN-ASVKPGH*P 663
            DG     + V  +DTW A+  LV  GLV+S+G++N  +  +  ++   A  K  H P
Sbjct: 150 RDGTPAIDTSVTLLDTWTAMNRLVDRGLVKSIGLANCTTAHVNDLVKAVAEAKLAHLP 207


>UniRef50_A2QL02 Cluster: Putative frameshift; n=1; Aspergillus
           niger|Rep: Putative frameshift - Aspergillus niger
          Length = 357

 Score =  136 bits (329), Expect = 2e-30
 Identities = 89/249 (35%), Positives = 132/249 (53%), Gaps = 8/249 (3%)
 Frame = +1

Query: 133 TLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQE 312
           TL+ GAKIP +G+GT++  P    + V   +  G R I  A VYG E++VG  IK    +
Sbjct: 39  TLNTGAKIPALGVGTFQD-PDSQEETVCQVLQRGMRLIDTARVYGVEQQVGRGIK----K 93

Query: 313 GVVKREDLFITSKLW-NTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFP 489
             V RE++F+ +KLW N FH PD V  A++ SLR+L   Y+DL L+H+P  +K  +  FP
Sbjct: 94  SGVPREEIFLGTKLWCNDFH-PDDVERAVDDSLRDLYTPYVDLLLMHYPCTFKRGEDRFP 152

Query: 490 TDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPGH*PGR 669
            DA+G++   +  +VDTW+ALE +V  G VR++GVSNF+  +++ +L   S  P      
Sbjct: 153 RDAEGRMIHGETTFVDTWRALEKVVKTGKVRAIGVSNFSKGEIETLLRETSTVPAVHQME 212

Query: 670 MPSVFKPXAIEAVLRRP*YYDNGVLPRWGXPD----RPWAKPGDPHLM---EDPKLKEIA 828
           +    +       LR    +     P     D      W+K    H+M   + P LKEI 
Sbjct: 213 VHPYLQQKGFNEWLREKGIHVVQFSPLGNMNDFYRQAGWSKE-IAHMMRVIDQPILKEIG 271

Query: 829 DRLGKXAAQ 855
            + GK   Q
Sbjct: 272 QKYGKSPVQ 280


>UniRef50_P14065 Cluster: Protein GCY; n=13; Saccharomycetales|Rep:
           Protein GCY - Saccharomyces cerevisiae (Baker's yeast)
          Length = 312

 Score =  136 bits (329), Expect = 2e-30
 Identities = 74/180 (41%), Positives = 113/180 (62%), Gaps = 9/180 (5%)
 Frame = +1

Query: 118 SVPVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIK 297
           S  + +L+ GA+IP IG+GTW+SK  +  +AV  A+  GYRHI  A +Y NE +VG+AIK
Sbjct: 8   STKILSLNTGAQIPQIGLGTWQSKENDAYKAVLTALKDGYRHIDTAAIYRNEDQVGQAIK 67

Query: 298 TKIQEGVVKREDLFITSKLWNT-FHRPDLVRGALEVSLRNLNIDYLDLYLIHWP----QA 462
               +  V RE++F+T+KLW T  H P++   AL+ SL+ L +DY+DLYL+HWP     A
Sbjct: 68  ----DSGVPREEIFVTTKLWCTQHHEPEV---ALDQSLKRLGLDYVDLYLMHWPARLDPA 120

Query: 463 Y--KEDDAIFPTDADGK--IQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRIL 630
           Y   ED    PT  DG   +  ++ +++ TW+ ++ L   G  +++GVSNF+   L+ +L
Sbjct: 121 YIKNEDILSVPTKKDGSRAVDITNWNFIKTWELMQELPKTGKTKAVGVSNFSINNLKDLL 180



 Score = 36.3 bits (80), Expect = 2.2
 Identities = 15/32 (46%), Positives = 19/32 (59%)
 Frame = +2

Query: 659 NQVECHPYLNXKRLKQFCEDRDIMITXYSPXG 754
           NQVE HP L    L  FC+ + I++  YSP G
Sbjct: 192 NQVEIHPLLPQDELINFCKSKGIVVEAYSPLG 223


>UniRef50_UPI0000519CC2 Cluster: PREDICTED: similar to CG2767-PA;
           n=1; Apis mellifera|Rep: PREDICTED: similar to CG2767-PA
           - Apis mellifera
          Length = 321

 Score =  136 bits (328), Expect = 2e-30
 Identities = 68/173 (39%), Positives = 106/173 (61%), Gaps = 2/173 (1%)
 Frame = +1

Query: 136 LSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQEG 315
           L NG  +P+IG GTW+++  E+  A+  A++ GYRHI  A  Y NEK +G+ +K      
Sbjct: 8   LPNGELMPIIGFGTWQAQEKELEDALNIALEAGYRHIDTATSYENEKVIGDVLKNWFDSK 67

Query: 316 VVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAY-KEDDAIFPT 492
            +KR D+FI +KL    +R + V   ++ SL+NL ++YLDLYLIH P  + K  D + P 
Sbjct: 68  KLKRSDIFIVTKLPAVGNRAEDVEKWIKTSLQNLRLEYLDLYLIHVPIGFEKVGDILHPF 127

Query: 493 DADGKIQF-SDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVK 648
           D +G I+  +  ++V+ W  +E  V  G  +++G+SNFN  Q++RIL N  +K
Sbjct: 128 DENGHIRLDNSTNHVEIWAEMEKQVKCGRTKAIGLSNFNISQIKRILKNTKMK 180



 Score = 37.1 bits (82), Expect = 1.3
 Identities = 15/31 (48%), Positives = 19/31 (61%)
 Frame = +2

Query: 662 QVECHPYLNXKRLKQFCEDRDIMITXYSPXG 754
           Q+E H Y   K L +FC+  +I IT YSP G
Sbjct: 185 QIELHVYFQQKELVKFCKQENIPITAYSPLG 215


>UniRef50_A5E082 Cluster: GCY protein; n=4; Saccharomycetales|Rep:
           GCY protein - Lodderomyces elongisporus (Yeast)
           (Saccharomyces elongisporus)
          Length = 295

 Score =  134 bits (325), Expect = 5e-30
 Identities = 72/184 (39%), Positives = 109/184 (59%), Gaps = 2/184 (1%)
 Frame = +1

Query: 100 SNLIMTSVPVTTLSNGAKIPVIGIGTWKSKPGEVT-QAVKDAIDIGYRHIXCAFVYGNEK 276
           S+ +  +    TL+NG KIP IG+GTW +   +   +A   A+  GY+HI  A  YGNE 
Sbjct: 2   SSQLSINTKTYTLNNGLKIPAIGLGTWLADEEDAAYKATLTALKNGYKHIDTAAAYGNED 61

Query: 277 EVGEAIKTKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWP 456
           +VG AI     +  V R+++F+T+KLWN  H+     GAL+ SL+ L ++Y+DLYLIHWP
Sbjct: 62  QVGRAIA----DSGVSRDEIFVTTKLWNDQHKDP--EGALDESLKKLGLEYVDLYLIHWP 115

Query: 457 QAYKEDDAIFPTDADGKIQFSDVDYVDTWKALEPLVCHG-LVRSLGVSNFNSKQLQRILD 633
                       D   +  + D D+VDTW+ L+ +   G  V+++GVSNFN K+L ++L+
Sbjct: 116 ---------LSVDPKTEKPYDDYDFVDTWRNLQKIYKEGKKVKAIGVSNFNKKKLDKLLN 166

Query: 634 NASV 645
           +  V
Sbjct: 167 SEGV 170



 Score = 37.1 bits (82), Expect = 1.3
 Identities = 16/34 (47%), Positives = 20/34 (58%)
 Frame = +2

Query: 653 VTNQVECHPYLNXKRLKQFCEDRDIMITXYSPXG 754
           V NQ+E HP L    L  + + +DI IT YSP G
Sbjct: 175 VINQIEAHPLLTQPDLFDYLKSKDIYITAYSPLG 208


>UniRef50_A3LTU8 Cluster: D-arabinose dehydrogenase; n=5;
           Saccharomycetales|Rep: D-arabinose dehydrogenase -
           Pichia stipitis (Yeast)
          Length = 326

 Score =  134 bits (323), Expect = 8e-30
 Identities = 82/212 (38%), Positives = 127/212 (59%), Gaps = 10/212 (4%)
 Frame = +1

Query: 136 LSNGAKIPVIGIGTWKSK-PGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQE 312
           LSNG  IP +G+GT   + P E+ + V  A+  GYRHI  A+ YG E+ +G+A+K   +E
Sbjct: 12  LSNGKTIPALGLGTVPPEDPHELKEQVITAVKAGYRHIDTAWYYGTEEYIGQALKQLFEE 71

Query: 313 GVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIF-- 486
           G+VKREDLFIT+K+W +F R      +L+ SL +L +DY+DL+L HWP     D+     
Sbjct: 72  GIVKREDLFITTKVWPSFWRNP--EKSLDKSLADLGLDYVDLFLQHWPVVLHGDENGLPP 129

Query: 487 -PTDADGKIQFSD-----VDYVDTWKALEPLVCH-GLVRSLGVSNFNSKQLQRILDNASV 645
            P D DGK+ + D     + Y+D + +LE ++ +   V+S+GVSN++  +L+++L  A+V
Sbjct: 130 QPRDKDGKLIYDDDPVSGIKYIDAYHSLEDIMDNTSKVKSIGVSNYSIPKLRKLL--AAV 187

Query: 646 KPGH*PGRMPSVFKPXAIEAVLRRP*YYDNGV 741
           +  H P      + P   +  L +   YDNGV
Sbjct: 188 RK-HKPVVNQIEYHPLLPQQDLVKY-CYDNGV 217



 Score = 36.7 bits (81), Expect = 1.7
 Identities = 15/34 (44%), Positives = 21/34 (61%)
 Frame = +2

Query: 653 VTNQVECHPYLNXKRLKQFCEDRDIMITXYSPXG 754
           V NQ+E HP L  + L ++C D  + I+ YSP G
Sbjct: 193 VVNQIEYHPLLPQQDLVKYCYDNGVHISAYSPVG 226


>UniRef50_Q8WRT0 Cluster: 3-dehydrecdysone 3b-reductase; n=1;
           Trichoplusia ni|Rep: 3-dehydrecdysone 3b-reductase -
           Trichoplusia ni (Cabbage looper)
          Length = 308

 Score =  132 bits (320), Expect = 2e-29
 Identities = 75/178 (42%), Positives = 107/178 (60%), Gaps = 2/178 (1%)
 Frame = +1

Query: 124 PVTTLSNGAKIPVIGIGTWK-SKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKT 300
           P+  L++G  IP + +GT+      +V QAV  AI  GYRHI  A +YGNE+EVG+ I  
Sbjct: 25  PLKQLNDGNAIPSLALGTFGFGDIPKVRQAVLWAIQAGYRHIDTAALYGNEEEVGKGIAD 84

Query: 301 KIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKED-D 477
            IQ+G+VKRE+LF+T+KLWN  H    V  AL  SL  L + Y+DLYLIH P+A  E+ D
Sbjct: 85  AIQQGLVKREELFVTTKLWNDKHGRHQVVPALRESLTKLGLSYVDLYLIHSPEATNENGD 144

Query: 478 AIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKP 651
            +            D+D ++TW  +E     GL +S+GVSNF++  L R++  ++  P
Sbjct: 145 PV------------DIDVLNTWNGMEEAKKLGLAKSIGVSNFDTALLDRLIAGSNTVP 190


>UniRef50_P38115 Cluster: D-arabinose dehydrogenase [NAD(P)+] heavy
           chain; n=3; Saccharomycetaceae|Rep: D-arabinose
           dehydrogenase [NAD(P)+] heavy chain - Saccharomyces
           cerevisiae (Baker's yeast)
          Length = 344

 Score =  132 bits (320), Expect = 2e-29
 Identities = 79/187 (42%), Positives = 111/187 (59%), Gaps = 14/187 (7%)
 Frame = +1

Query: 133 TLSNGAKIPVIGIGTWK--SKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKI 306
           +L+NG +IP +G+GT     K  E  QAVK AI  GYRHI  A+ Y  E  VGEAIK  +
Sbjct: 26  SLNNGVRIPALGLGTANPHEKLAETKQAVKAAIKAGYRHIDTAWAYETEPFVGEAIKELL 85

Query: 307 QEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAY---KEDD 477
           ++G +KREDLFIT+K+W      D V  +L  SL+ L ++Y+DL L HWP  +   K+  
Sbjct: 86  EDGSIKREDLFITTKVWPVLW--DEVDRSLNESLKALGLEYVDLLLQHWPLCFEKIKDPK 143

Query: 478 AI-----FPTDADGKIQF-SDVDYVDTWKALEPLVC---HGLVRSLGVSNFNSKQLQRIL 630
            I      P D  GK  + +D DY++T+K LE +        VR++GVSNF+ + L+R++
Sbjct: 144 GISGLVKTPVDDSGKTMYAADGDYLETYKQLEKIYLDPNDHRVRAIGVSNFSIEYLERLI 203

Query: 631 DNASVKP 651
               VKP
Sbjct: 204 KECRVKP 210



 Score = 41.5 bits (93), Expect = 0.060
 Identities = 17/32 (53%), Positives = 22/32 (68%)
 Frame = +2

Query: 659 NQVECHPYLNXKRLKQFCEDRDIMITXYSPXG 754
           NQVE HP+L    L++FC   DI++T YSP G
Sbjct: 213 NQVETHPHLPQMELRKFCFMHDILLTAYSPLG 244


>UniRef50_Q5T2L2 Cluster: Aldo-keto reductase family 1 member C-like
           protein 1; n=14; Eutheria|Rep: Aldo-keto reductase
           family 1 member C-like protein 1 - Homo sapiens (Human)
          Length = 302

 Score =  132 bits (319), Expect = 2e-29
 Identities = 66/141 (46%), Positives = 93/141 (65%), Gaps = 4/141 (2%)
 Frame = +1

Query: 136 LSNGAKIPVIGIGTWK---SKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKI 306
           L++G  +PV+G GT+    +   +  +A K AID+G+RHI  A++Y NE+EVG+AI  KI
Sbjct: 13  LNDGPFMPVLGFGTYAPDHTPKSQAAEATKVAIDVGFRHIDSAYLYQNEEEVGQAIWEKI 72

Query: 307 QEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKE-DDAI 483
            +G VKRE++F T KLW TF R +LV  ALE SL+ L  DY+DL++IH P A K+    +
Sbjct: 73  ADGTVKREEIFYTIKLWATFFRAELVHPALERSLKKLGPDYVDLFIIHVPFAMKQPGKEL 132

Query: 484 FPTDADGKIQFSDVDYVDTWK 546
            P DA G+I    V+  DTW+
Sbjct: 133 LPKDASGEIILETVELCDTWE 153



 Score = 45.2 bits (102), Expect = 0.005
 Identities = 20/39 (51%), Positives = 26/39 (66%)
 Frame = +2

Query: 638 PL*NQVTNQVECHPYLNXKRLKQFCEDRDIMITXYSPXG 754
           P  NQV   VECHPYLN  +L +FC+ +DI++  YS  G
Sbjct: 167 PTCNQV---VECHPYLNQSKLLEFCKSKDIVLVAYSALG 202


>UniRef50_Q968S3 Cluster: Aldoketoreductase-like protein; n=1;
           Orconectes limosus|Rep: Aldoketoreductase-like protein -
           Orconectes limosus (Spinycheek crayfish)
          Length = 336

 Score =  132 bits (318), Expect = 3e-29
 Identities = 86/257 (33%), Positives = 132/257 (51%), Gaps = 9/257 (3%)
 Frame = +1

Query: 112 MTSVPVTTLSNGAKIPVIGIGTW------KSKPGEVTQAVKDAIDIGYRHIXCAFVYGNE 273
           MT +P   L++G+ IPV+G+GT       K     VT  ++ A++ GYRH   A  YGNE
Sbjct: 8   MTKIPTILLNSGSHIPVMGLGTGSLGRNGKMSEEAVTAVLETALECGYRHFDSAAYYGNE 67

Query: 274 KEVGEAIKTKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHW 453
             +G+ ++  I EG VKRE+LFIT+KL    +R   V   L+ SL NL + Y+DLYL+H+
Sbjct: 68  AIIGQVLRRWISEGKVKREELFITTKLPTRGNREKDVARFLQKSLDNLRLPYVDLYLVHY 127

Query: 454 PQAYKEDDAIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILD 633
           P    + D      AD        D    W+A+E  +  G  +++G+SNFN+ Q+QRI+ 
Sbjct: 128 PCGILDTDR-ERLSADEVTVDPTTDIHAIWRAMEAQLAAGKTKNIGLSNFNADQVQRIIK 186

Query: 634 NASVKPGH*PGRMPSVFKPXAIEAVLRRP*YYDNGVLPRWG--XPDRPWAKPGDPH-LME 804
              V+P      +    +  A+ A   +         P  G     R  ++PG+   L+E
Sbjct: 187 GCQVRPAVLQVEVHVYMQQGALRAFCAQHDIVVCAFCPLGGPFRLIRKASRPGEVKLLLE 246

Query: 805 DPKLKEIADRLGKXAAQ 855
           DP++ ++A    K  AQ
Sbjct: 247 DPQVLDVATAHHKTPAQ 263


>UniRef50_P22045 Cluster: Probable reductase; n=101; cellular
           organisms|Rep: Probable reductase - Leishmania major
          Length = 284

 Score =  132 bits (318), Expect = 3e-29
 Identities = 75/176 (42%), Positives = 103/176 (58%), Gaps = 1/176 (0%)
 Frame = +1

Query: 127 VTTLSNGAKIPVIGIGTWKSKPGEVTQ-AVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTK 303
           + TLSNG K+P  G+G W+S  GEVT+ AV  A+  GYRHI  A +Y NE+ VG  ++  
Sbjct: 8   MVTLSNGVKMPQFGLGVWQSPAGEVTENAVNWALCAGYRHIDTAAIYKNEESVGAGLRAS 67

Query: 304 IQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAI 483
                V RED+FIT+KLWNT    +    A E S + L +DY+DLYLIHWP+     D +
Sbjct: 68  ----GVPREDVFITTKLWNTEQGYESTLAAFEESRQKLGVDYIDLYLIHWPRG---KDIL 120

Query: 484 FPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKP 651
                +GK       Y+D+W+A E L     VR++GVSNF+   L+ +L   +V P
Sbjct: 121 ---SKEGK------KYLDSWRAFEQLYKEKKVRAIGVSNFHIHHLEDVLAMCTVTP 167



 Score = 35.9 bits (79), Expect = 3.0
 Identities = 18/47 (38%), Positives = 27/47 (57%), Gaps = 2/47 (4%)
 Frame = +2

Query: 653 VTNQVECHPYLNXKRLKQFCEDRDIMITXYSP--XGXLPTDPGLSLV 787
           + NQVE HP  N   L+ FC+ + I +  +SP   G L ++P LS +
Sbjct: 168 MVNQVELHPLNNQADLRAFCDAKQIKVEAWSPLGQGKLLSNPILSAI 214


>UniRef50_Q7N0E4 Cluster: 2,5-diketo-D-gluconic acid reductase A;
           n=2; Bacteria|Rep: 2,5-diketo-D-gluconic acid reductase
           A - Photorhabdus luminescens subsp. laumondii
          Length = 292

 Score =  130 bits (315), Expect = 8e-29
 Identities = 72/180 (40%), Positives = 101/180 (56%)
 Frame = +1

Query: 112 MTSVPVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEA 291
           M + P+  L++G  +P +G+G+W S   ++ + +  A+DIGYR I  A +Y NEK VG A
Sbjct: 1   MDNQPIIRLADGNHMPQLGLGSWASDDQQIAETIHAALDIGYRAIDTAAIYNNEKGVGNA 60

Query: 292 IKTKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKE 471
               +QE  + RED+F+T+KLWN  H     R AL  SL  L +DY+DLYLIHWP     
Sbjct: 61  ----LQETDIPREDIFVTTKLWNDRHLD--ARAALTESLEKLQLDYVDLYLIHWPAP--- 111

Query: 472 DDAIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKP 651
                P D           YV  W+ L  L   GL+RS+GVSNF  + +QR+++   V P
Sbjct: 112 -----PQD----------QYVGAWQQLIELQKEGLIRSIGVSNFQPEHIQRLINETGVHP 156


>UniRef50_Q41E86 Cluster: 2,5-didehydrogluconate reductase; n=2;
           Bacteria|Rep: 2,5-didehydrogluconate reductase -
           Exiguobacterium sibiricum 255-15
          Length = 274

 Score =  130 bits (315), Expect = 8e-29
 Identities = 87/242 (35%), Positives = 126/242 (52%), Gaps = 1/242 (0%)
 Frame = +1

Query: 133 TLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQE 312
           TL+NG  +P +G G +K    EV +AV++A+ +GYR I  A +Y NE  VG A+K    +
Sbjct: 5   TLNNGLVMPQLGYGVFKVPEQEVYEAVREALRVGYRSIDTAMIYENEAGVGRALK----D 60

Query: 313 GVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPT 492
             + RED+F+T+K+WN     +    A E SL+ L +DY+DLYLIHWP    ++D     
Sbjct: 61  SGIPREDIFLTTKVWNKDQGYERTLAAFETSLQKLGVDYVDLYLIHWPM--PDEDL---- 114

Query: 493 DADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPGH*PGRM 672
                       Y+DTW+ALE L   G  +++GVSNF+   L R+L+  +V P      +
Sbjct: 115 ------------YMDTWRALEQLYRDGKAKAIGVSNFHIPHLTRVLEEGTVVPAVNQIEL 162

Query: 673 PSVFKPXAIEAVLRRP*YYDNG-VLPRWGXPDRPWAKPGDPHLMEDPKLKEIADRLGKXA 849
                  AI A  ++     NG V+  W     P  K  D   + DP + +IA R GK  
Sbjct: 163 HPFLSQEAIRAFCQK-----NGIVVEAWS----PLMKGRD--ALTDPVITDIAARHGKTP 211

Query: 850 AQ 855
           AQ
Sbjct: 212 AQ 213


>UniRef50_Q8J0K1 Cluster: 4-dihydromethyltrisporate dehydrogenase;
           n=2; Parasitella parasitica|Rep:
           4-dihydromethyltrisporate dehydrogenase - Parasitella
           parasitica
          Length = 321

 Score =  130 bits (315), Expect = 8e-29
 Identities = 71/174 (40%), Positives = 99/174 (56%), Gaps = 7/174 (4%)
 Frame = +1

Query: 151 KIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQEGVVKRE 330
           K+P+ G G WK +  +    +  AI IGYR    A  YGNE EVG  I   I+EG+VKRE
Sbjct: 14  KMPLRGFGCWKIEKKDAENTIYQAIKIGYRLFDGACDYGNEVEVGRGINKAIKEGLVKRE 73

Query: 331 DLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHW--PQAYKEDDAIFPTD--- 495
           +LFI +KLWNTFH    VR A +  L++  ++Y DLYLIH+  P  Y +    +P +   
Sbjct: 74  ELFIVTKLWNTFHSKQHVRTAFDRQLKDWGLEYFDLYLIHFPIPLQYVDPAVSYPPEWYV 133

Query: 496 --ADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKP 651
             AD K+ F      + W  +E LV   L R++GV+NFN + +  +L  A +KP
Sbjct: 134 PHAD-KLNFERSPIHECWAEMEKLVQAKLTRNIGVANFNCQAILDLLSYAKIKP 186


>UniRef50_Q4Q5N9 Cluster: Prostaglandin f synthase, putative; n=7;
           cellular organisms|Rep: Prostaglandin f synthase,
           putative - Leishmania major
          Length = 279

 Score =  130 bits (313), Expect = 1e-28
 Identities = 86/241 (35%), Positives = 122/241 (50%)
 Frame = +1

Query: 133 TLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQE 312
           TLSNG ++P +GIGTW++K G     +K A++ GYRH+  A  Y NEK VG+     I E
Sbjct: 9   TLSNGVQVPQLGIGTWEAKDGNEVVNIKWAVNAGYRHVDTAHYYKNEKGVGQG----ISE 64

Query: 313 GVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPT 492
             V R D+F+T+KLWN  H  +    A E S + L ++Y+DLYLIHWP   +        
Sbjct: 65  CGVPRSDIFVTTKLWNYDHGYESALAAFEQSRQALGVEYVDLYLIHWPGPNR-------- 116

Query: 493 DADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPGH*PGRM 672
                       Y++TW+A E L     VR++GVSNF    L  +L N +V P      M
Sbjct: 117 -----------SYIETWRAFEKLYEMKKVRAIGVSNFEPHHLDDLLANCTVPPMVNQVEM 165

Query: 673 PSVFKPXAIEAVLRRP*YYDNGVLPRWGXPDRPWAKPGDPHLMEDPKLKEIADRLGKXAA 852
              F+  A+ A         N  +  W    RP  K     L+ +P+L E+A++  + AA
Sbjct: 166 HPHFQQKALRAYCAE----KNIAVTAW----RPLGKGA---LLTEPQLVELAEKHKRSAA 214

Query: 853 Q 855
           Q
Sbjct: 215 Q 215


>UniRef50_A6ESC0 Cluster: ARA1; n=1; unidentified eubacterium
           SCB49|Rep: ARA1 - unidentified eubacterium SCB49
          Length = 280

 Score =  128 bits (308), Expect = 5e-28
 Identities = 71/173 (41%), Positives = 100/173 (57%), Gaps = 1/173 (0%)
 Frame = +1

Query: 136 LSNGAKIPVIGIGTWKSKPGEVT-QAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQE 312
           L+N   IP IG GTW++  G+    A+K AID GY+HI  A +Y NEK VG  IK    E
Sbjct: 7   LNNNINIPAIGFGTWQTPDGQTAINAIKTAIDAGYKHIDAAAIYKNEKGVGLGIK----E 62

Query: 313 GVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPT 492
             + R+DLF+TSK+WN     +    A + ++ +L +DYLDLYLIHWP A  +       
Sbjct: 63  ANIDRKDLFVTSKVWNEQRGYENTLKAFDNTINDLQLDYLDLYLIHWPAAAHQ------- 115

Query: 493 DADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKP 651
             +   Q ++    DTW A+E L   G +++LGVSNF    L  +L +A++KP
Sbjct: 116 -FENWKQLNN----DTWSAMEKLYKDGKIKALGVSNFMEHHLTPLLQHATIKP 163


>UniRef50_UPI00015B4912 Cluster: PREDICTED: similar to aldo-keto
           reductase; n=1; Nasonia vitripennis|Rep: PREDICTED:
           similar to aldo-keto reductase - Nasonia vitripennis
          Length = 353

 Score =  127 bits (307), Expect = 7e-28
 Identities = 80/251 (31%), Positives = 125/251 (49%), Gaps = 8/251 (3%)
 Frame = +1

Query: 127 VTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKI 306
           V  LS+G   P++G+GT       +   +  A++ G  HI  +FVY NE+ +G+ +K   
Sbjct: 30  VYRLSSGHNFPIVGLGTHGLNEDVLETVLTGALEKGIGHIDTSFVYKNEETIGKVLKDWF 89

Query: 307 QEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQA--YKEDDA 480
            +G  KRED+F+TSKL    + P+ V   +++SL  L + YLD+YLIH P A  +KED  
Sbjct: 90  AKGG-KREDIFVTSKLPYYDNHPESVEKYIKLSLEKLGLQYLDMYLIHAPFAVHHKEDSY 148

Query: 481 IFPTDADGKIQF-SDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPGH 657
              T+ DG +   +  D +  WK +E  V  G  +S+G+SNFN  Q+  IL  A +KP +
Sbjct: 149 ELATNEDGSVVLDTQTDPIAVWKEMEKQVKEGRTKSIGLSNFNETQITNILKEAKIKPSN 208

Query: 658 *PGRMPSVFKPXAIEAVLRRP*YYDNGVLPRWGXPDRPWAKPGD-----PHLMEDPKLKE 822
               + +  +   +    ++      G  P      R    PG      P + + P + E
Sbjct: 209 LQVEVHAYHQQKPLIEFCQKNGIIVTGYAPLGSPGARKELHPGQMEEEFPDVFKLPVVNE 268

Query: 823 IADRLGKXAAQ 855
           IA + GK   Q
Sbjct: 269 IAKKHGKSVVQ 279


>UniRef50_Q7PM68 Cluster: ENSANGP00000014386; n=1; Anopheles gambiae
           str. PEST|Rep: ENSANGP00000014386 - Anopheles gambiae
           str. PEST
          Length = 310

 Score =  127 bits (307), Expect = 7e-28
 Identities = 66/167 (39%), Positives = 94/167 (56%), Gaps = 1/167 (0%)
 Frame = +1

Query: 154 IPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQE-GVVKRE 330
           +P IG+GT+     +  +A++ AID+GYR    A  YGNE  VGEAI+ KI+E   + R+
Sbjct: 17  LPTIGLGTYSILGADGKEAIRTAIDVGYRMFDTAVAYGNEAIVGEAIREKIRECNNLTRD 76

Query: 331 DLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTDADGKI 510
           D FI SKL  ++HR DLV     ++L  L +DY+DLYL+H P A + +            
Sbjct: 77  DFFIISKLSGSYHRQDLVEKCCRMTLDRLGMDYVDLYLMHTPVALQSEKKCARNGTKLNA 136

Query: 511 QFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKP 651
               +   + W  LE     GL RS+GVSNFN  Q+  +L +AS+ P
Sbjct: 137 IDDSIAPTEAWIGLEQCYQEGLCRSIGVSNFNEHQINALLSDASIVP 183



 Score = 35.1 bits (77), Expect = 5.2
 Identities = 11/32 (34%), Positives = 22/32 (68%)
 Frame = +2

Query: 659 NQVECHPYLNXKRLKQFCEDRDIMITXYSPXG 754
           NQ+EC    N + +++FC+ ++I++  Y+P G
Sbjct: 186 NQIECSIGFNQRPMRKFCQQQNILVMGYTPLG 217


>UniRef50_UPI0000D56CE5 Cluster: PREDICTED: similar to CG6084-PA,
           isoform A; n=1; Tribolium castaneum|Rep: PREDICTED:
           similar to CG6084-PA, isoform A - Tribolium castaneum
          Length = 493

 Score =  126 bits (305), Expect = 1e-27
 Identities = 76/197 (38%), Positives = 110/197 (55%), Gaps = 9/197 (4%)
 Frame = +1

Query: 292 IKTKIQEGVVKREDLFITSKLWNTFH-RPD---LVRGALEVSLRNLNIDYLDLYLIHWPQ 459
           +K  +Q G +   D+ I S  +  F+  P+    +      SL+NL +DYLD+YL+HWP 
Sbjct: 231 LKYNVQLGNIVISDMLIESANFFDFYLAPEDMSYISTFSSESLKNLQLDYLDVYLMHWPH 290

Query: 460 AYKEDDAIFPTDAD-GKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDN 636
           A KE  ++ P D   G    SDVD+VDTWKA+E +    L +S+G+SNFNS Q+ R+L +
Sbjct: 291 ALKEGPSLHPIDPKTGLFIPSDVDFVDTWKAMEKMHEKDLTKSIGISNFNSNQIDRLLKS 350

Query: 637 ASVKPGH*PGRMPSVFKPXAIEAVLRRP*YYDNGV----LPRWGXPDRPWAKPGDPHLME 804
           A +     P        P   ++ LR+    D G+        G P RPW KPGDP+++ 
Sbjct: 351 AKIA----PVINQIECHPYLNQSKLRK-FCSDRGITVTSYSPLGSPARPWQKPGDPYVIN 405

Query: 805 DPKLKEIADRLGKXAAQ 855
           DPK+KEI ++ GK  AQ
Sbjct: 406 DPKIKEIGNKYGKSPAQ 422



 Score =  108 bits (259), Expect = 5e-22
 Identities = 66/180 (36%), Positives = 106/180 (58%)
 Frame = +1

Query: 112 MTSVPVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEA 291
           M  +P+  L+NG +IPV G+   +    EV + V+  +   YR + C+ ++ NEK  G A
Sbjct: 5   MRDIPIAKLNNGIEIPVFGLAAPQDF-FEV-ENVQLVVSSNYRLMDCS-IFENEKRFGVA 61

Query: 292 IKTKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKE 471
           ++  I+ G ++R+DLF+ SK   T +  +LV+ AL  +L+ L + YLDLYLI  P A K 
Sbjct: 62  LQQLIEGGKIRRKDLFLMSKFCCT-NTTNLVKAALLDTLKKLQVAYLDLYLIERPPACK- 119

Query: 472 DDAIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKP 651
                           D + ++TW+A+E L    L R++G+SNFNSKQ++RIL+N +++P
Sbjct: 120 ----------------DHNLIETWEAMEGLYSEKLTRAIGLSNFNSKQIERILENCTIRP 163



 Score = 56.0 bits (129), Expect = 3e-06
 Identities = 21/34 (61%), Positives = 26/34 (76%)
 Frame = +2

Query: 653 VTNQVECHPYLNXKRLKQFCEDRDIMITXYSPXG 754
           V NQ+ECHPYLN  +L++FC DR I +T YSP G
Sbjct: 356 VINQIECHPYLNQSKLRKFCSDRGITVTSYSPLG 389



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 15/32 (46%), Positives = 23/32 (71%)
 Frame = +2

Query: 659 NQVECHPYLNXKRLKQFCEDRDIMITXYSPXG 754
           NQ++CHPYLN  +L+++C +  I +  YSP G
Sbjct: 166 NQIQCHPYLNQAKLRKYCSNNGIAVISYSPLG 197


>UniRef50_Q01HB5 Cluster: OSIGBa0136O08-OSIGBa0153H12.9 protein;
           n=4; Oryza sativa|Rep: OSIGBa0136O08-OSIGBa0153H12.9
           protein - Oryza sativa (Rice)
          Length = 337

 Score =  126 bits (305), Expect = 1e-27
 Identities = 75/184 (40%), Positives = 105/184 (57%), Gaps = 5/184 (2%)
 Frame = +1

Query: 115 TSVPVTTLSNGAKIPVIGIGTWKSKP-GEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEA 291
           T+VP  TL++G  +PV+G GT  S P  ++   +  A+ +GYRH+  A VYG E  VG A
Sbjct: 18  TAVPCVTLNSGHAMPVLGFGTGSSTPPADLAATIAHAVRLGYRHLDTAAVYGTEGAVGAA 77

Query: 292 IKTKIQEGVV-KREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAY- 465
           +   ++ G V  R +LF+T+KL      P  V  AL  SL  L +DY+DL+LIHWP A  
Sbjct: 78  VAEAVRCGAVASRGELFVTTKLSMADAHPPRVVAALRESLSRLGLDYVDLFLIHWPVAIG 137

Query: 466 KEDDAIFPTDADGKIQFSDVDYVDTWKALEPLVCH--GLVRSLGVSNFNSKQLQRILDNA 639
           K+D A   T  D        D    W+ +E   CH  GL RS+GVSNF++ ++ R+L  A
Sbjct: 138 KKDAAGELTWDDLSRGLVPFDMEGVWRGMEE--CHRLGLARSIGVSNFSAAKMSRLLALA 195

Query: 640 SVKP 651
           +V P
Sbjct: 196 AVPP 199


>UniRef50_Q7G764 Cluster: Probable NAD(P)H-dependent oxidoreductase
           1; n=32; Eukaryota|Rep: Probable NAD(P)H-dependent
           oxidoreductase 1 - Oryza sativa subsp. japonica (Rice)
          Length = 321

 Score =  126 bits (305), Expect = 1e-27
 Identities = 86/256 (33%), Positives = 138/256 (53%), Gaps = 8/256 (3%)
 Frame = +1

Query: 112 MTSVPVTTLSNGAK-IPVIGIGTWK---SKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKE 279
           M ++P    S   + +P +G+GT     +   + T A+  AI++GYRH   A +Y  E  
Sbjct: 1   MATIPEVPASELIQTMPRVGMGTAAFPFTSSEDTTAAMLRAIELGYRHFDTARIYATEGC 60

Query: 280 VGEAIKTKIQEGVV-KREDLFITSKLW-NTFHRPDLVRGALEVSLRNLNIDYLDLYLIHW 453
           VGEA+   ++ G++  R D+F+TSK+W +  H   +V  A E +LRNL +DY+DL L+HW
Sbjct: 61  VGEAVAEAVRRGLIASRADVFVTSKIWCSDLHAGRVVPAARE-TLRNLGMDYVDLLLVHW 119

Query: 454 PQAYKEDDAIFPTDADGKIQFSDVDYVDTWKALEPLVCH--GLVRSLGVSNFNSKQLQRI 627
           P +    +  FP   +  +   D++ V  W+ +E   CH  GL R++GVSNF++K+L+++
Sbjct: 120 PVSLTPGNYDFPFPKEVILPSFDMEGV--WRGMEE--CHRLGLARAIGVSNFSAKKLEQL 175

Query: 628 LDNASVKPGH*PGRMPSVFKPXAIEAVLRRP*YYDNGVLPRWGXPDRPWAKPGDPHLMED 807
           L  A+V+P      +  +++   +  V RR      G  P  G    PW   G   +M+ 
Sbjct: 176 LSLAAVRPAVNQVEVNPMWQQRTLREVCRREGVQLCGYSP-LGAKGTPW---GSAAVMDS 231

Query: 808 PKLKEIADRLGKXAAQ 855
             L+EIA   GK  AQ
Sbjct: 232 GVLQEIAGAKGKTLAQ 247


>UniRef50_Q03TW0 Cluster: Aldo/keto reductase of diketogulonate
           reductase family; n=1; Lactobacillus brevis ATCC
           367|Rep: Aldo/keto reductase of diketogulonate reductase
           family - Lactobacillus brevis (strain ATCC 367 / JCM
           1170)
          Length = 293

 Score =  126 bits (304), Expect = 2e-27
 Identities = 73/183 (39%), Positives = 107/183 (58%), Gaps = 1/183 (0%)
 Frame = +1

Query: 106 LIMTSVPVTTLSNGAKIPVIGIGTWKSKPGEVTQ-AVKDAIDIGYRHIXCAFVYGNEKEV 282
           ++   +P   ++NG +IP +G+G ++    E T+ A+K A+  GYRHI  A  YGNE+ V
Sbjct: 6   ILHNDIPDLPMNNGHQIPQLGLGVFQVDNAEDTKNAIKWALAAGYRHIDTAAYYGNEQWV 65

Query: 283 GEAIKTKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQA 462
           GEAI+    E  V R+ +F+TSKLWN+    D  + A + +L  L +DYLDLYLIHWP  
Sbjct: 66  GEAIR----ESDVPRDQIFVTSKLWNSVRGYDETQAAFQETLDKLGLDYLDLYLIHWP-- 119

Query: 463 YKEDDAIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNAS 642
                      A G        Y+D+W+A+E L   G ++++GVSNFN  Q+  IL + +
Sbjct: 120 -----------APG--------YLDSWRAMEDLYKAGKIKNIGVSNFNQTQMADILAHGT 160

Query: 643 VKP 651
           VKP
Sbjct: 161 VKP 163


>UniRef50_Q8ZI40 Cluster: 2,5-diketo-D-gluconic acid reductase A;
           n=74; Bacteria|Rep: 2,5-diketo-D-gluconic acid reductase
           A - Yersinia pestis
          Length = 277

 Score =  126 bits (303), Expect = 2e-27
 Identities = 73/181 (40%), Positives = 102/181 (56%), Gaps = 1/181 (0%)
 Frame = +1

Query: 112 MTSVPVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEA 291
           MT  P+  L +G  +P +G+G W++   E   AV  A+++GYR I  A +Y NE+ VG+A
Sbjct: 1   MTMQPLIKLYDGRLMPQLGLGVWQASIQETELAVSKALEVGYRSIDTAAIYKNEEGVGKA 60

Query: 292 IKTKIQEGVVKREDLFITSKLWN-TFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYK 468
           +K       V R++LFIT+KLWN   H P   + ALE SL+ L +DY+DLYLIHWP   K
Sbjct: 61  LKA----AAVARDELFITTKLWNDDQHNP---QQALETSLQKLQLDYVDLYLIHWPDP-K 112

Query: 469 EDDAIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVK 648
           +D                  YV  W+ L  L   GL+RS+GV NF+   LQR++D   + 
Sbjct: 113 QD-----------------HYVSAWRELVTLKEQGLIRSIGVCNFHIPHLQRLIDETGIA 155

Query: 649 P 651
           P
Sbjct: 156 P 156


>UniRef50_Q9ZBW7 Cluster: Putative oxidoreductase; n=2;
           Actinomycetales|Rep: Putative oxidoreductase -
           Streptomyces coelicolor
          Length = 277

 Score =  125 bits (301), Expect = 4e-27
 Identities = 72/179 (40%), Positives = 98/179 (54%)
 Frame = +1

Query: 115 TSVPVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAI 294
           + VP   L+NG ++P +G G W+    +   AV  A++ GYR I  A +YGNE+  G AI
Sbjct: 3   SKVPPIILNNGVEMPQLGFGVWQVPDDDAQTAVALALEAGYRSIDTAAIYGNEEGTGRAI 62

Query: 295 KTKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKED 474
                 G+  REDLF+T+KLWN+    D    A + S+  L ++YLDLYLIHWP   KE 
Sbjct: 63  AAS---GLA-REDLFVTTKLWNSDQGYDSTLRAFDTSMAKLGLEYLDLYLIHWPMPAKE- 117

Query: 475 DAIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKP 651
                             YVDT+KA E L+  G VR++GVSNF  + L+R+    SV P
Sbjct: 118 -----------------RYVDTYKAFEKLLADGRVRAIGVSNFLPEHLERLTAETSVIP 159


>UniRef50_Q7G765 Cluster: Probable NAD(P)H-dependent oxidoreductase
           2; n=6; Magnoliophyta|Rep: Probable NAD(P)H-dependent
           oxidoreductase 2 - Oryza sativa subsp. japonica (Rice)
          Length = 322

 Score =  124 bits (300), Expect = 5e-27
 Identities = 86/241 (35%), Positives = 126/241 (52%), Gaps = 7/241 (2%)
 Frame = +1

Query: 154 IPVIGIGTWK---SKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQEGVV- 321
           +P IG+GT     +   E T A+  AI++GYRH   A +Y  E  V EA+   ++ G+V 
Sbjct: 18  MPRIGMGTAAFPFTSSEETTAALLRAIELGYRHFDTARLYATEGCVSEAVAEAVRRGLVA 77

Query: 322 KREDLFITSKLW-NTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTDA 498
            R D+F+TSKLW +  H   +V  A E +LRNL +DY+DL L+HWP         FP   
Sbjct: 78  SRADVFVTSKLWCSDLHAGRVVPAARE-TLRNLGMDYVDLLLVHWPATVAPGSYDFPFPK 136

Query: 499 DGKIQFSDVDYVDTWKALEPLVCH--GLVRSLGVSNFNSKQLQRILDNASVKPGH*PGRM 672
           +      D++ V  W+ +E   CH  GL R++GVSNF++K+L+++L  A V+P      M
Sbjct: 137 EEMAPAFDMEGV--WRGMEE--CHRLGLARAIGVSNFSAKKLEQLLSFAVVRPAANQVEM 192

Query: 673 PSVFKPXAIEAVLRRP*YYDNGVLPRWGXPDRPWAKPGDPHLMEDPKLKEIADRLGKXAA 852
             +++   +  V RR      G  P  G    PW   G   +M+   L +IA   GK  A
Sbjct: 193 NPMWQQRTLREVCRREGVQLCGYSP-LGAKGTPW---GSAAVMDSGVLHDIAQTKGKTLA 248

Query: 853 Q 855
           Q
Sbjct: 249 Q 249


>UniRef50_P70883 Cluster: AkrI; n=1; Butyrivibrio fibrisolvens|Rep:
           AkrI - Butyrivibrio fibrisolvens
          Length = 172

 Score =  124 bits (298), Expect = 9e-27
 Identities = 69/167 (41%), Positives = 93/167 (55%), Gaps = 1/167 (0%)
 Frame = +1

Query: 136 LSNGAKIPVIGIGTWKSKP-GEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQE 312
           L+NG  IP+ G GT+K K   E   +V+ A+  GYRHI  A  Y NEK V  AIK  ++E
Sbjct: 10  LNNGTAIPMFGYGTYKIKDQNEAYNSVRLALKNGYRHIDTAAFYENEKFVANAIKDFMEE 69

Query: 313 GVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPT 492
              KRED+F+TSK W T    D    A E ++  + +DYLDLYL+HWP +Y  DD    T
Sbjct: 70  SQTKREDIFVTSKAWKTELGYDKTLAAFEKTMNEMQMDYLDLYLVHWPASYAFDDDWENT 129

Query: 493 DADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILD 633
           +              TWKA+  +   G V+++GVSNF +  L  I+D
Sbjct: 130 NRQ------------TWKAMTEIYKSGRVKAIGVSNFLTHHLDTIID 164


>UniRef50_Q9HGY0 Cluster: Glycerol dehydrogenase; n=8;
           Saccharomycetaceae|Rep: Glycerol dehydrogenase -
           Zygosaccharomyces rouxii (Candida mogii)
          Length = 310

 Score =  124 bits (298), Expect = 9e-27
 Identities = 69/187 (36%), Positives = 107/187 (57%), Gaps = 7/187 (3%)
 Frame = +1

Query: 109 IMTSVPVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGE 288
           +  S     L+ G  IP +G+GTW+SK  E  +AV +A+  GYRHI  A VYGNE EVG+
Sbjct: 4   LQNSTSTLKLNTGQTIPQVGLGTWRSKENEGYKAVIEALKAGYRHIDGAAVYGNEGEVGK 63

Query: 289 AIKTKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYK 468
           A    IQ+  V R ++F+T+KLW T  R    + AL+ SL+ L +DY+ LYL+HWP   +
Sbjct: 64  A----IQDSGVPRNEIFLTTKLWCTHQRNP--QEALDQSLQRLGLDYVGLYLVHWPVPLR 117

Query: 469 EDDA------IFPTDADGKIQFS-DVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRI 627
            ++        F    DG      + +++ TW+ ++ L+  G  +++GVSNF+   L+ +
Sbjct: 118 TENIKDGNLFQFAEKPDGSKDVDLEWNFIKTWELMQKLLESGKTKAIGVSNFSVNNLKDL 177

Query: 628 LDNASVK 648
           L   + K
Sbjct: 178 LAAPTTK 184



 Score = 38.3 bits (85), Expect = 0.55
 Identities = 16/32 (50%), Positives = 21/32 (65%)
 Frame = +2

Query: 659 NQVECHPYLNXKRLKQFCEDRDIMITXYSPXG 754
           NQVE HP L  + L Q+C ++ I+I  YSP G
Sbjct: 190 NQVEFHPLLPQEELIQYCSEKGIVIEAYSPLG 221


>UniRef50_Q9X0A2 Cluster: Oxidoreductase, aldo/keto reductase
           family; n=21; Bacteria|Rep: Oxidoreductase, aldo/keto
           reductase family - Thermotoga maritima
          Length = 286

 Score =  123 bits (297), Expect = 1e-26
 Identities = 83/246 (33%), Positives = 131/246 (53%), Gaps = 1/246 (0%)
 Frame = +1

Query: 121 VPVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKT 300
           VP  TL+NG ++P++G G ++  P +  + V +AI +GYR I  A  Y NE+ VG AIK 
Sbjct: 3   VPKVTLNNGVEMPILGYGVFQIPPEKTEECVYEAIKVGYRLIDTAASYMNEEGVGRAIKR 62

Query: 301 KIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDA 480
            I EG+V+RE+LF+T+KLW +    +  + A E SL+ L ++Y+DLYLIH P        
Sbjct: 63  AIDEGIVRREELFVTTKLWVSDVGYESTKKAFEKSLKKLQLEYIDLYLIHQP-------- 114

Query: 481 IFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPGH* 660
                      F DV     WKA+E +   GLVR++GVSNF   +L  ++ +  + P   
Sbjct: 115 -----------FGDVHC--AWKAMEEMYKDGLVRAIGVSNFYPDRLMDLMVHHEIVPAVN 161

Query: 661 PGRMPSVFKPXAIEAVLRRP*YYDNGVLPR-WGXPDRPWAKPGDPHLMEDPKLKEIADRL 837
              +   ++       +R     +  + P  WG    P+A+ G  ++ ++  L+ IA++ 
Sbjct: 162 QIEIHPFYQRQEEIEFMR-----NYNIQPEAWG----PFAE-GRKNIFQNGVLRSIAEKY 211

Query: 838 GKXAAQ 855
           GK  AQ
Sbjct: 212 GKTVAQ 217


>UniRef50_Q7VG53 Cluster: Aldo-keto reductase; n=28; Bacteria|Rep:
           Aldo-keto reductase - Helicobacter hepaticus
          Length = 292

 Score =  123 bits (297), Expect = 1e-26
 Identities = 70/173 (40%), Positives = 101/173 (58%)
 Frame = +1

Query: 133 TLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQE 312
           TL+NG KIP +G+GTW+     V  AV++A  +GYRHI  A  YGNE+ VGEA++    +
Sbjct: 16  TLNNGNKIPKLGLGTWRIDDNVVEAAVREAFKVGYRHIDTAQAYGNERGVGEAVR----K 71

Query: 313 GVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPT 492
             +KRE+LFITSK+   +        +++ SL+ + +D++DL LIH PQ         P 
Sbjct: 72  SKIKREELFITSKIRAEYKDYKSASASIDTSLKTMKLDFIDLMLIHSPQ---------PW 122

Query: 493 DADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKP 651
           ++  K  +   + V+ + ALE     G VRS+GVSNF  K L+ IL N   KP
Sbjct: 123 NSFRKGDYFK-ENVEVYNALEDAQKAGKVRSIGVSNFLQKDLENILKNCKTKP 174


>UniRef50_Q05KR9 Cluster: Benzil reductase; n=5; Bacillales|Rep:
           Benzil reductase - Bacillus subtilis
          Length = 276

 Score =  123 bits (297), Expect = 1e-26
 Identities = 76/173 (43%), Positives = 98/173 (56%), Gaps = 1/173 (0%)
 Frame = +1

Query: 136 LSNGAKIPVIGIGTWKSKPG-EVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQE 312
           L NG ++P  G+G +K + G E T++VK AI  GYR I  A +Y NE+ VG  IK    E
Sbjct: 11  LHNGVEMPWFGLGVFKVENGNEATESVKAAIKNGYRSIDTAAIYKNEEGVGIGIK----E 66

Query: 313 GVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPT 492
             V RE+LFITSK+WN     +    A E SL  L +DYLDLYLIHWP            
Sbjct: 67  SGVAREELFITSKVWNEDQGYETTLAAFEKSLERLQLDYLDLYLIHWP------------ 114

Query: 493 DADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKP 651
              GK +     Y DTW+ALE L   G +R++GVSNF    L+ +L +A +KP
Sbjct: 115 ---GKDK-----YKDTWRALEKLYKDGKIRAIGVSNFQVHHLEELLKDAEIKP 159


>UniRef50_A6RKL9 Cluster: Putative uncharacterized protein; n=3;
           Sclerotiniaceae|Rep: Putative uncharacterized protein -
           Botryotinia fuckeliana B05.10
          Length = 360

 Score =  123 bits (296), Expect = 2e-26
 Identities = 68/170 (40%), Positives = 100/170 (58%), Gaps = 3/170 (1%)
 Frame = +1

Query: 157 PVIGIGTWKSK--PGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQEGVVKRE 330
           P+IG GTW  K  P   T+AV  AI+IGYR I CA VYGNE  VG  I+  ++   +KRE
Sbjct: 40  PLIGFGTWNLKVSPENTTEAVAYAIEIGYRQIDCAAVYGNEVAVGRGIEEGLKRAGLKRE 99

Query: 331 DLFITSKLWNTFHRP-DLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTDADGK 507
           D+++TSKLWN  H   + V   L  +L++L ++YLDLYLIHWP  +  + A         
Sbjct: 100 DIWVTSKLWNDHHGSYENVEKGLNQTLQDLGLEYLDLYLIHWPIGFSSNGA--------- 150

Query: 508 IQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPGH 657
               ++D+V T+K++  L     V ++GVSNF+  QL+ ++   ++   H
Sbjct: 151 ---KNLDHVQTYKSMISLP-KSRVLNIGVSNFSPLQLKNVVSTGTIPYMH 196


>UniRef50_Q03XK0 Cluster: Aldo/keto reductase of diketogulonate
           reductase family; n=3; Lactobacillales|Rep: Aldo/keto
           reductase of diketogulonate reductase family -
           Leuconostoc mesenteroides subsp. mesenteroides (strain
           ATCC 8293 /NCDO 523)
          Length = 292

 Score =  122 bits (295), Expect = 2e-26
 Identities = 70/174 (40%), Positives = 102/174 (58%), Gaps = 1/174 (0%)
 Frame = +1

Query: 133 TLSNGAKIPVIGIGTWK-SKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQ 309
           TL++G ++P++G G ++  + G   QAV DAI  GYR I  A  YGNE+EVGEAI   I 
Sbjct: 5   TLASGIEMPLLGFGVFQVQEKGAAKQAVLDAIKTGYRLIDTAASYGNEREVGEAILEAIN 64

Query: 310 EGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFP 489
           +G+VKRE+LF+TSK+W           A++ SL+ LN+DYLDLYLIH P           
Sbjct: 65  QGIVKREELFVTSKMWVQDVSAQQATAAIQSSLQRLNLDYLDLYLIHQP----------- 113

Query: 490 TDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKP 651
                   ++DV     W+A+E     G ++++GVSNF+  QL  + + + +KP
Sbjct: 114 --------YNDV--FGAWRAMESAYRSGQLKAIGVSNFDIAQLTNLAEFSDIKP 157


>UniRef50_Q7R2T6 Cluster: GLP_291_56367_57278; n=1; Giardia lamblia
           ATCC 50803|Rep: GLP_291_56367_57278 - Giardia lamblia
           ATCC 50803
          Length = 303

 Score =  122 bits (295), Expect = 2e-26
 Identities = 64/169 (37%), Positives = 92/169 (54%), Gaps = 4/169 (2%)
 Frame = +1

Query: 157 PVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQEGV--VKRE 330
           P +G GT+  +  E   A++ A+ +GYRH  CA+ YGNE+ +GE  K    +    VKRE
Sbjct: 6   PCVGFGTYLVEDPE---AIRSAVKLGYRHFDCAYRYGNERMIGEVFKEIFNDDSYGVKRE 62

Query: 331 DLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKE--DDAIFPTDADG 504
           DL+I SKLW  FH P+ V   +  +LR+L ++YLD++L+HWP A K   D     +D  G
Sbjct: 63  DLWIVSKLWPNFHEPEKVAYQISETLRDLQLEYLDVFLMHWPLAIKHLADRDYASSDGKG 122

Query: 505 KIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKP 651
                      TW+A+E  V     R +GVSN  +  L  +L    +KP
Sbjct: 123 GTLLGTTPIRKTWEAMEACVDKKQTRFIGVSNMGTAMLVDLLSYCRIKP 171



 Score = 35.9 bits (79), Expect = 3.0
 Identities = 15/33 (45%), Positives = 17/33 (51%)
 Frame = +2

Query: 656 TNQVECHPYLNXKRLKQFCEDRDIMITXYSPXG 754
           TNQ E  PY    RL +FC    I +T Y P G
Sbjct: 173 TNQFESQPYFPNDRLIEFCNSNGIYVTAYRPLG 205


>UniRef50_UPI00006CD296 Cluster: oxidoreductase, aldo/keto reductase
           family protein; n=1; Tetrahymena thermophila SB210|Rep:
           oxidoreductase, aldo/keto reductase family protein -
           Tetrahymena thermophila SB210
          Length = 295

 Score =  122 bits (294), Expect = 3e-26
 Identities = 65/175 (37%), Positives = 104/175 (59%), Gaps = 1/175 (0%)
 Frame = +1

Query: 130 TTLSNGAKIPVIGIGTWKS-KPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKI 306
           T L NG+K+PV G+GT+K     E+   ++ A+D+GYRHI  A +Y NEK++G+A++   
Sbjct: 8   TELCNGSKLPVFGLGTYKVVSKEEMVTFLRTALDLGYRHIDTAIMYENEKQIGDALQEIY 67

Query: 307 QEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIF 486
           +EG  KREDLF+ +KL++  ++   V   +  SL+NL  +Y+DLYL+H+  +        
Sbjct: 68  KEGKYKREDLFLVTKLFS--NKNTKVEDQVRQSLQNLQTNYIDLYLLHYASSP------- 118

Query: 487 PTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKP 651
           PTD   + + +       W   E LV  GL+R++G+SNFN + L  +     +KP
Sbjct: 119 PTD---QFELTHKPVFQVWAEFEELVQKGLIRNIGISNFNVQMLLDLYSYCKIKP 170


>UniRef50_Q8F1G4 Cluster: Aldehyde reductase; n=8; Bacteria|Rep:
           Aldehyde reductase - Leptospira interrogans
          Length = 278

 Score =  122 bits (294), Expect = 3e-26
 Identities = 69/173 (39%), Positives = 100/173 (57%), Gaps = 1/173 (0%)
 Frame = +1

Query: 136 LSNGAKIPVIGIGTWKSKPG-EVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQE 312
           L+NG  +P++G+G WK+K G E  +AV +A++ GYRHI  A +Y NE +VG+AI+    E
Sbjct: 14  LNNGISMPILGLGVWKTKSGKECKEAVLNALEAGYRHIDTARIYDNEVDVGQAIR----E 69

Query: 313 GVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPT 492
             + R+++FIT+KLWN     D  R ALE SL  L ID++DLYLIH+P   K        
Sbjct: 70  SGIPRKEIFITTKLWNADQGSDKTRKALENSLDRLGIDFVDLYLIHFPVTSKR------- 122

Query: 493 DADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKP 651
                        +D+WK LE L    L +++GVSN+    L  +L N+ + P
Sbjct: 123 -------------MDSWKELEKLYHDKLCKAIGVSNYTIIHLTELLKNSQITP 162



 Score = 35.9 bits (79), Expect = 3.0
 Identities = 14/30 (46%), Positives = 19/30 (63%)
 Frame = +2

Query: 659 NQVECHPYLNXKRLKQFCEDRDIMITXYSP 748
           NQVE HP+LN   L ++C+   I +  YSP
Sbjct: 165 NQVEFHPFLNQIHLLEYCKKHKIQLEAYSP 194


>UniRef50_A6NPD6 Cluster: Putative uncharacterized protein; n=3;
           Bacteria|Rep: Putative uncharacterized protein -
           Bacteroides capillosus ATCC 29799
          Length = 287

 Score =  121 bits (291), Expect = 6e-26
 Identities = 72/172 (41%), Positives = 98/172 (56%)
 Frame = +1

Query: 136 LSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQEG 315
           LSNG  IP +G GT+K+  G+ +  + +AI  GYRH   A  YG E  +G+A+     E 
Sbjct: 10  LSNGLSIPAVGFGTYKTGDGD-SAVLSNAIAQGYRHFDTASFYGTETALGQAVA----ES 64

Query: 316 VVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTD 495
            + RED F+TSKLW T    D    A + +L  L  DYLDLYLIHWP+   E +      
Sbjct: 65  DIPREDFFLTSKLWKTEMGYDAALRAFDATLERLGTDYLDLYLIHWPRPDLELE------ 118

Query: 496 ADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKP 651
                 ++ +D  +TW+ALE L   GLVR++GVSNF    L+ IL +A+V P
Sbjct: 119 -----DWAKLDR-ETWRALERLYESGLVRAIGVSNFLPHHLEPILASANVAP 164


>UniRef50_Q7XY49 Cluster: Mannose 6-phosphate reductase; n=1;
           Griffithsia japonica|Rep: Mannose 6-phosphate reductase
           - Griffithsia japonica (Red alga)
          Length = 174

 Score =  121 bits (291), Expect = 6e-26
 Identities = 59/110 (53%), Positives = 71/110 (64%)
 Frame = +1

Query: 118 SVPVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIK 297
           S    TL +GAK+P+ G GTWK+   E  QAV  A+  GYRHI CA VY NE  VG AI 
Sbjct: 2   STNTATLQSGAKMPLNGFGTWKASVEETEQAVTAALRAGYRHIDCAAVYWNEAAVGTAIS 61

Query: 298 TKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLI 447
             I  GVVKREDLFITSK+WNT H  D V  +   SL++  +DY DL+L+
Sbjct: 62  KAISGGVVKREDLFITSKVWNTCHATDKVVDSCRQSLKDHQVDYFDLFLV 111


>UniRef50_Q4PDR0 Cluster: Putative uncharacterized protein; n=1;
           Ustilago maydis|Rep: Putative uncharacterized protein -
           Ustilago maydis (Smut fungus)
          Length = 339

 Score =  121 bits (291), Expect = 6e-26
 Identities = 72/190 (37%), Positives = 112/190 (58%), Gaps = 12/190 (6%)
 Frame = +1

Query: 118 SVPVTTLSNGAKIPVIGIGTWKSKPG-----EVTQAVKDAIDIGYRHIXCAFVYGNEKEV 282
           ++P  TL+ GAK+P +G+G W+ +PG     E+  A+  AI +GYRH+  A  Y NE EV
Sbjct: 4   NIPSFTLNTGAKLPSVGMGCWQGQPGPGRDNELVDALVRAIKVGYRHLDTATGYRNEAEV 63

Query: 283 GEAIKTKIQEGVVKREDLFITSKLW-NTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQ 459
           G+A++   Q GV  R ++F+T+KL     H  D+V+  LE SL  L IDY+DL+L+HWPQ
Sbjct: 64  GQAVR---QSGVA-RSEIFVTTKLRPGGVH--DVVQ-ELENSLNELGIDYIDLWLLHWPQ 116

Query: 460 AYKEDDAIFPTDADGKIQFS---DVDYVDTWKALEPLVCH---GLVRSLGVSNFNSKQLQ 621
            + +DD  F T     ++        + +TW  +E +  +   G V+++GVSNF+ K L+
Sbjct: 117 GFTKDDGGFGTGESFGLEHQKHLGPTFNETWAKMEDVFLNSHKGKVKAIGVSNFSIKNLE 176

Query: 622 RILDNASVKP 651
            +   + V P
Sbjct: 177 ILAKTSKVTP 186



 Score = 40.3 bits (90), Expect = 0.14
 Identities = 15/32 (46%), Positives = 21/32 (65%)
 Frame = +2

Query: 659 NQVECHPYLNXKRLKQFCEDRDIMITXYSPXG 754
           NQ+E HPYL    L ++C+ + I +T YSP G
Sbjct: 189 NQIEAHPYLPEHELVKYCKHKSIHVTAYSPLG 220


>UniRef50_Q6NII7 Cluster: Putative oxidoreductase; n=2;
           Corynebacterium|Rep: Putative oxidoreductase -
           Corynebacterium diphtheriae
          Length = 290

 Score =  120 bits (289), Expect = 1e-25
 Identities = 63/177 (35%), Positives = 101/177 (57%)
 Frame = +1

Query: 121 VPVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKT 300
           +P  TL++G ++P IG GT+K +  +  +AV+ AI++GYRHI  A +Y NE+EVG A+  
Sbjct: 11  IPTITLNDGTEMPAIGFGTYKLREQDAYRAVRSAIEVGYRHIDTASLYKNEEEVGRAVAD 70

Query: 301 KIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDA 480
            I  G V R++LFIT+K+WN  H   L + + + SL  L +DY+D  ++HWP   K    
Sbjct: 71  AITAGEVARDELFITTKVWNDMHGDQLTQRSFQESLHRLGLDYIDCCMVHWPWPQK---- 126

Query: 481 IFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKP 651
                  G        YV+++ AL  +   G ++S+ V+NF  + L+ I+    + P
Sbjct: 127 -------GL-------YVESFAALAKIQGLGQLQSVAVANFYPEVLREIVAETGIAP 169


>UniRef50_A0JRJ3 Cluster: 2,5-didehydrogluconate reductase; n=3;
           Actinobacteria (class)|Rep: 2,5-didehydrogluconate
           reductase - Arthrobacter sp. (strain FB24)
          Length = 276

 Score =  120 bits (289), Expect = 1e-25
 Identities = 70/180 (38%), Positives = 96/180 (53%)
 Frame = +1

Query: 112 MTSVPVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEA 291
           M   PV  L++G +IP IG+GTW     +V  AV +A++ GYRHI  A  YGNEK VG  
Sbjct: 1   MALSPVIELNDGHRIPQIGLGTWPLDDHQVAAAVVNAVEGGYRHIDTAVKYGNEKGVGNG 60

Query: 292 IKTKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKE 471
           I++      + R +LFIT+KL   F   D     L+ SL+ L +DY+DL LIHWP   ++
Sbjct: 61  IRS----SGLDRSELFITTKLDGEFQGQDRAVAGLDGSLKRLGLDYVDLLLIHWPLPRRD 116

Query: 472 DDAIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKP 651
                             +++ TWK  E L   G VRS+GVSNF    L+R++    V P
Sbjct: 117 ------------------EFISTWKTFERLQADGKVRSIGVSNFKPAHLERLMAACDVVP 158


>UniRef50_A7CUW0 Cluster: 2,5-didehydrogluconate reductase; n=6;
           Bacteria|Rep: 2,5-didehydrogluconate reductase -
           Opitutaceae bacterium TAV2
          Length = 334

 Score =  120 bits (288), Expect = 1e-25
 Identities = 83/248 (33%), Positives = 118/248 (47%)
 Frame = +1

Query: 112 MTSVPVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEA 291
           M  +P   LS+G  IP +G+G W+         ++ A + GYR I  A +YGNE+ VG A
Sbjct: 56  MRMIPTLPLSDGTSIPQLGLGVWQMPDDGAGVPIQAAFNAGYRAIDTAPIYGNEEGVGRA 115

Query: 292 IKTKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKE 471
           I+       + R++L+IT+K+WN+    D    A+  SL  L ++Y+DLYLIHWP     
Sbjct: 116 IRAS----GLPRKELYITTKVWNSAQGYDSTLRAVRESLGRLQLEYVDLYLIHWPVP--- 168

Query: 472 DDAIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKP 651
                      KI      YVDTWKAL  +   GL RS+GVSNF    LQR+ D   + P
Sbjct: 169 -----------KID----RYVDTWKALAKIKADGLARSIGVSNFTPVYLQRLFDETGIVP 213

Query: 652 GH*PGRMPSVFKPXAIEAVLRRP*YYDNGVLPRWGXPDRPWAKPGDPHLMEDPKLKEIAD 831
                    V     +   L++  +       +       W+  G   L+ DP L  IA 
Sbjct: 214 ---------VVNQVELHPRLQQ--HELRAFHAKHRIVTEAWSPLGQGTLLADPVLAGIAQ 262

Query: 832 RLGKXAAQ 855
           + G+ AAQ
Sbjct: 263 KHGRSAAQ 270


>UniRef50_Q11BF8 Cluster: Aldo/keto reductase; n=12; Bacteria|Rep:
           Aldo/keto reductase - Mesorhizobium sp. (strain BNC1)
          Length = 308

 Score =  119 bits (287), Expect = 2e-25
 Identities = 79/240 (32%), Positives = 131/240 (54%), Gaps = 2/240 (0%)
 Frame = +1

Query: 142 NGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQEGVV 321
           +G ++P+IG+G +++ P E T AV++A+ +GYRHI  A  YGNE+EVGE I+   + G+ 
Sbjct: 25  SGVEMPMIGLGVFQTPPDETTAAVEEALRLGYRHIDTAAAYGNEREVGEGIR---RAGIA 81

Query: 322 KREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTDAD 501
            R+++FI +K+W + +  D    A + S   L +D +DL L+H P          P+  D
Sbjct: 82  -RDEVFIETKIWISDYGYDETLHAFDKSAGKLGVDQIDLLLLHQP---------LPSAFD 131

Query: 502 GKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPGH*PGRMPSV 681
             +          ++ALE L+  G VR++GVSNF  + L R+L   S+ P      +   
Sbjct: 132 RTL--------GAYRALEKLLADGKVRAIGVSNFMPEHLTRLLTETSIVPAVNQIEVHPY 183

Query: 682 FKPXAIEAVLRRP*YYDNGVLPRWGXP--DRPWAKPGDPHLMEDPKLKEIADRLGKXAAQ 855
           F+  A++ +     + ++G+L +   P     + + G+   +EDP L EIA + GK AAQ
Sbjct: 184 FQQRALQRL-----HAEHGILTQAWSPIGGITFYRGGEKSTLEDPVLLEIAQQHGKSAAQ 238


>UniRef50_A6LZ55 Cluster: 2,5-didehydrogluconate reductase; n=1;
           Clostridium beijerinckii NCIMB 8052|Rep:
           2,5-didehydrogluconate reductase - Clostridium
           beijerinckii NCIMB 8052
          Length = 289

 Score =  119 bits (287), Expect = 2e-25
 Identities = 64/171 (37%), Positives = 99/171 (57%), Gaps = 1/171 (0%)
 Frame = +1

Query: 142 NGAKIPVIGIGTWKSKPGEVTQ-AVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQEGV 318
           NG KIP +G G +K   GE  + AV +AI IGYRH   A +YGNEK++G AI    ++  
Sbjct: 12  NGIKIPQVGFGVYKLNKGEDFETAVGEAIKIGYRHFDTAKIYGNEKDLGLAI----EKSQ 67

Query: 319 VKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTDA 498
           + RE+ FITSK+WNT H  +  + A E + + LN++YLD+YLIH+  +Y           
Sbjct: 68  IPREEFFITSKVWNTDHGYEATKKAFEQTCKKLNVEYLDMYLIHFASSY----------- 116

Query: 499 DGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKP 651
                     Y++TW A+E L   G ++ +GV+NF  + L+ ++ ++ + P
Sbjct: 117 ----------YLETWHAMEELYLQGKIKVIGVANFQIQHLEELMKHSRITP 157


>UniRef50_UPI00015B5BD7 Cluster: PREDICTED: similar to aldo-keto
           reductase; n=1; Nasonia vitripennis|Rep: PREDICTED:
           similar to aldo-keto reductase - Nasonia vitripennis
          Length = 310

 Score =  119 bits (286), Expect = 2e-25
 Identities = 74/176 (42%), Positives = 109/176 (61%), Gaps = 4/176 (2%)
 Frame = +1

Query: 136 LSNGAKIPVIGIGTWKSKPGEVTQAVKD-AIDIGYRHIXCAFVYGNEKEVGEAIKTKIQE 312
           L+NG  +P++GIGT+K +  EV + V D +  +G+R I  A VY NE+++G A+K  + +
Sbjct: 28  LNNGYDMPLVGIGTYKVRGREVIKRVIDESFAVGFRSIDTAVVYRNEEDIGLALKELLPK 87

Query: 313 GVVKREDLFITSKLWNTFH-RPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFP 489
             +KRED+FITSKL  + +  PD +R ++E SL+ L+  YLDLYLIHWP A +    I  
Sbjct: 88  YNLKREDIFITSKLSPSDNGDPDKIRKSVEDSLKALDTSYLDLYLIHWPGASR----ILE 143

Query: 490 TDADG-KIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNAS-VKP 651
              D  K++      V TW  L  L   GL+RS+GVSN+    L+ +L++ S VKP
Sbjct: 144 NSPDNPKLR------VTTWATLVELQQKGLLRSIGVSNYTVGHLEHLLEHCSGVKP 193



 Score = 35.9 bits (79), Expect = 3.0
 Identities = 15/36 (41%), Positives = 19/36 (52%)
 Frame = +2

Query: 659 NQVECHPYLNXKRLKQFCEDRDIMITXYSPXGXLPT 766
           NQVECHP+     L +FC  + I +  YS  G   T
Sbjct: 196 NQVECHPHFRQDELIEFCTKQGIHVQAYSSLGTSDT 231


>UniRef50_Q68ST9 Cluster: Reductase AKOR2; n=2; Pleurotus
           djamor|Rep: Reductase AKOR2 - Pleurotus djamor
          Length = 306

 Score =  119 bits (286), Expect = 2e-25
 Identities = 70/187 (37%), Positives = 106/187 (56%), Gaps = 7/187 (3%)
 Frame = +1

Query: 112 MTSVPVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKD----AIDIGYRHIXCAFVYGNEKE 279
           M++ P   L+ GA++P + +G W     E     K+    A+  GYRHI  A +Y  EK 
Sbjct: 1   MSAYPPIVLNTGARMPALALGGWAGLTEEERTQAKEWFLTALKSGYRHIDTAQIYYTEKS 60

Query: 280 VGEAIKTKIQEGVVKREDLFITSKL-WNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWP 456
           VG AI+    E  + RE+LFIT+KL WN   R   V  + + SL NL  +Y+DLYL+H+P
Sbjct: 61  VGNAIR----ESGIPREELFITTKLPWNHHSR---VAESFQKSLENLGTEYIDLYLVHFP 113

Query: 457 Q-AYKEDDAIFPTDADGKIQFSDVDYV-DTWKALEPLVCHGLVRSLGVSNFNSKQLQRIL 630
           Q  + ++   FP + DG I+  +   + D W  +E L+  G V+++GVSN++ K L+ +L
Sbjct: 114 QRVFYDETTDFPRNPDGSIKVVNSPTLNDVWADVETLLDTGKVKAIGVSNYSIKTLEELL 173

Query: 631 DNASVKP 651
             A V P
Sbjct: 174 KTAKVVP 180



 Score = 39.9 bits (89), Expect = 0.18
 Identities = 17/40 (42%), Positives = 26/40 (65%), Gaps = 2/40 (5%)
 Frame = +2

Query: 659 NQVECHPYLNXKRLKQFCEDRDIMITXYSPXG--XLPTDP 772
           NQVE HP+L   +L  +C+++ I +T Y+P G   + TDP
Sbjct: 183 NQVELHPFLAQSKLLAYCKEKGIAVTAYTPTGYQTVLTDP 222


>UniRef50_P06632 Cluster: 2,5-diketo-D-gluconic acid reductase A;
           n=8; Actinomycetales|Rep: 2,5-diketo-D-gluconic acid
           reductase A - Corynebacterium sp. (strain ATCC 31090)
          Length = 278

 Score =  119 bits (286), Expect = 2e-25
 Identities = 72/178 (40%), Positives = 99/178 (55%)
 Frame = +1

Query: 118 SVPVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIK 297
           +VP   L++G  IP +G G +K  P +  +AV++A+++GYRHI  A +YGNE+ VG AI 
Sbjct: 2   TVPSIVLNDGNSIPQLGYGVFKVPPADTQRAVEEALEVGYRHIDTAAIYGNEEGVGAAIA 61

Query: 298 TKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDD 477
                G+  R+DLFIT+KLWN  H  D    A+  SL  L +D +DLYL+HWP       
Sbjct: 62  A---SGIA-RDDLFITTKLWNDRHDGDEPAAAIAESLAKLALDQVDLYLVHWPT------ 111

Query: 478 AIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKP 651
              P  AD        +YV  W+ +  L   GL RS+GVSN     L+RI+    V P
Sbjct: 112 ---PA-AD--------NYVHAWEKMIELRAAGLTRSIGVSNHLVPHLERIVAATGVVP 157


>UniRef50_Q83N50 Cluster: 2,5-diketo-D-gluconic acid reductase; n=2;
           Tropheryma whipplei|Rep: 2,5-diketo-D-gluconic acid
           reductase - Tropheryma whipplei (strain Twist)
           (Whipple's bacillus)
          Length = 283

 Score =  118 bits (285), Expect = 3e-25
 Identities = 69/173 (39%), Positives = 101/173 (58%)
 Frame = +1

Query: 109 IMTSVPVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGE 288
           ++T VP   L +G  IP  G+GT++  P E +  V+ AI++GYRHI  A +Y NE+EVG 
Sbjct: 5   VLTYVPSVLLGDGVSIPQFGLGTYELPPNEASSVVQSAIELGYRHIDTASLYANEREVGR 64

Query: 289 AIKTKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYK 468
           AI +      +KRE+ F+T+KLWN+  +P   R A E SL  L++DY+DLYLIHWP    
Sbjct: 65  AIAS----SGIKREEFFVTTKLWNS-DQPK-PREAFERSLDLLSLDYVDLYLIHWPCP-- 116

Query: 469 EDDAIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRI 627
                 P++           Y++ W+ L  L   G  +S+GVSNF S+ + +I
Sbjct: 117 ------PSEL----------YINVWEVLLELKESGRAKSVGVSNFLSEHIDKI 153


>UniRef50_A7BA05 Cluster: Putative uncharacterized protein; n=1;
           Actinomyces odontolyticus ATCC 17982|Rep: Putative
           uncharacterized protein - Actinomyces odontolyticus ATCC
           17982
          Length = 292

 Score =  118 bits (284), Expect = 4e-25
 Identities = 68/177 (38%), Positives = 98/177 (55%)
 Frame = +1

Query: 121 VPVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKT 300
           +P   L  G+ IPV+G GT+K  P +   AV  A+++GYRHI  A +YGNE EVG A++ 
Sbjct: 16  IPTFMLPTGSPIPVLGFGTYKVAPEDTYDAVSRALEVGYRHIDTAQMYGNEAEVGAALEA 75

Query: 301 KIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDA 480
               G+  REDLFIT+K+ N+ H PD    ++  SL +L  DY+DL L+HWP        
Sbjct: 76  ---SGIA-REDLFITTKVDNSNHEPDRAAASIRRSLEDLRTDYVDLLLVHWP-------- 123

Query: 481 IFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKP 651
             PT   G       D    W ALE     G  R++G+SN+  + ++ + + A+V P
Sbjct: 124 -LPTLYGG-------DVALPWPALEDAFNAGGARAIGLSNYEREHVEAVREVATVAP 172


>UniRef50_Q838E0 Cluster: Oxidoreductase, aldo/keto reductase
           family; n=24; Bacilli|Rep: Oxidoreductase, aldo/keto
           reductase family - Enterococcus faecalis (Streptococcus
           faecalis)
          Length = 279

 Score =  117 bits (282), Expect = 7e-25
 Identities = 71/184 (38%), Positives = 95/184 (51%), Gaps = 2/184 (1%)
 Frame = +1

Query: 106 LIMTSVPVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVG 285
           +I +     TL+NG KIP +G+G ++    E  + V++ I  GYR I  A +YGNE   G
Sbjct: 1   MITSLADTVTLNNGTKIPGMGLGVFQIPDEETAKVVEEGIINGYRLIDTAQIYGNESGTG 60

Query: 286 EAIKTKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWP--Q 459
             IK  +    + REDLF+TSK+WN     D    A   SL  L +DYLDLYLIHWP   
Sbjct: 61  AGIKAGLAATGLNREDLFVTSKVWNAHISYDETIQAFNDSLERLGLDYLDLYLIHWPGNN 120

Query: 460 AYKEDDAIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNA 639
           +YKE                      +W+ALE L   G V+++GVSNF    L+ +L  A
Sbjct: 121 SYKE----------------------SWQALETLYAEGKVKAIGVSNFQVHHLEDLLSYA 158

Query: 640 SVKP 651
            V P
Sbjct: 159 KVVP 162



 Score = 39.9 bits (89), Expect = 0.18
 Identities = 16/32 (50%), Positives = 21/32 (65%)
 Frame = +2

Query: 653 VTNQVECHPYLNXKRLKQFCEDRDIMITXYSP 748
           V NQVE HP L+ K ++ FCE  DI +  +SP
Sbjct: 163 VINQVELHPKLDQKEVRDFCEKHDIKVQAWSP 194


>UniRef50_Q9ZUJ6 Cluster: T2K10.1 protein; n=16; core
           eudicotyledons|Rep: T2K10.1 protein - Arabidopsis
           thaliana (Mouse-ear cress)
          Length = 176

 Score =  117 bits (282), Expect = 7e-25
 Identities = 66/177 (37%), Positives = 100/177 (56%), Gaps = 8/177 (4%)
 Frame = +1

Query: 112 MTSVPVTTLSNGAK----IPVIGIGTWKS---KPGEVTQAVKDAIDIGYRHIXCAFVYGN 270
           +T+VP   + +G      +PV+G GT  S   +P  + + V +AI +GYRH   +  Y  
Sbjct: 3   LTTVPTLAIRSGPSGHHSMPVLGFGTAASPLPEPTMLKETVIEAIKLGYRHFDTSPRYQT 62

Query: 271 EKEVGEAIKTKIQEGVVK-REDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLI 447
           E+ +GEA+   +  G+V+ R + F+T+KLW       LV  A++ SL+NL +DYLDLY+I
Sbjct: 63  EEPIGEALAEAVSLGLVRSRSEFFVTTKLWCADAHGGLVVPAIKRSLKNLKLDYLDLYII 122

Query: 448 HWPQAYKEDDAIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQL 618
           HWP + K     FP D D    F  +D+   W  +E     GL + +GVSNF+ K+L
Sbjct: 123 HWPVSSKPGKYKFPIDED---DFMPMDFEVVWSEMEECQRLGLAKCIGVSNFSCKKL 176


>UniRef50_A7P424 Cluster: Chromosome chr1 scaffold_5, whole genome
           shotgun sequence; n=1; Vitis vinifera|Rep: Chromosome
           chr1 scaffold_5, whole genome shotgun sequence - Vitis
           vinifera (Grape)
          Length = 247

 Score =  117 bits (282), Expect = 7e-25
 Identities = 91/264 (34%), Positives = 132/264 (50%), Gaps = 16/264 (6%)
 Frame = +1

Query: 112 MTSVPVTTL-SNGAKIPVIGIGT--WKSKPGE-VTQAVKDAIDIGYRHIXCAFVYGNEKE 279
           M S+P  TL S G  IP++G+ T  +   P E +  ++  AI++GYRH  C   Y +EK 
Sbjct: 1   MISIPEMTLGSTGKAIPLVGMVTTVYPFAPSETMIDSILTAIELGYRHFDCVAAYLSEKP 60

Query: 280 VGEAIKTKIQEGVVK-REDLFITSKLWNTFHRPDLVRGALEVSLR---------NLNIDY 429
           +GEAIK  ++ G++K R++LFITSKLW +    D V  AL+ +L+         NL +DY
Sbjct: 61  LGEAIKKAVKLGLIKSRDELFITSKLWCSDAHHDRVLPALQNTLKISSILSFSKNLQLDY 120

Query: 430 LDLYLIHWPQAYKEDDAIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNS 609
           LDLYLIHW              +DG +    +D    WKA+E      L +++GVSNF+ 
Sbjct: 121 LDLYLIHW--------------SDGHLP---IDLGSVWKAMEDFQKLSLTKAIGVSNFSC 163

Query: 610 KQLQRILDNASVKP--GH*PGRMPSVFKPXAIEAVLRRP*YYDNGVLPRWGXPDRPWAKP 783
            +L+ +L  AS+ P         P++    A   +  R     +   P W  P   W   
Sbjct: 164 NKLEELLQTASILPAVNQVSENEPTLAAEEAQGVIYVRKRVSISRHTPPW-VPKEHW--- 219

Query: 784 GDPHLMEDPKLKEIADRLGKXAAQ 855
           G   +ME   LK+IA   G   AQ
Sbjct: 220 GTDRVMECEVLKKIARETGNSIAQ 243


>UniRef50_A3C1Z7 Cluster: Putative uncharacterized protein; n=2;
           Oryza sativa (japonica cultivar-group)|Rep: Putative
           uncharacterized protein - Oryza sativa subsp. japonica
           (Rice)
          Length = 288

 Score =  117 bits (282), Expect = 7e-25
 Identities = 80/253 (31%), Positives = 124/253 (49%), Gaps = 8/253 (3%)
 Frame = +1

Query: 121 VPVTTLSNGAKIPVIGIGTWK-----SKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVG 285
           +P   LS+G  +P +G+GT       + P  V   V  AI+ GYRH   A VY  E  +G
Sbjct: 1   MPEAALSSGKPMPRVGMGTASFPLGATDPSTVKDVVLRAIEAGYRHFDTAAVYQTEAILG 60

Query: 286 EAIKTKIQEGVV-KREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQA 462
           +A+   ++ G+V  R++L+ITSKLW     P  V  +L  +LR + ++YLDLYLIH+P +
Sbjct: 61  DAVAEAVRAGLVASRDELYITSKLWVAHAHPGHVLPSLRRALRKMQMEYLDLYLIHFPVS 120

Query: 463 YK--EDDAIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDN 636
            +  ED        D  +    +D    WK +E     GL +++GVSNF+ K+L+ +L  
Sbjct: 121 MRLAEDPESMTYSKDDLVM---MDMEGVWKEMEECQRLGLTKAIGVSNFSCKKLETLLSF 177

Query: 637 ASVKPGH*PGRMPSVFKPXAIEAVLRRP*YYDNGVLPRWGXPDRPWAKPGDPHLMEDPKL 816
           A++ P      +    +   +    +          P  G    PW+      +M+ P L
Sbjct: 178 ATISPAANQVEVHPYCRQNKLREFCKEKGIQLCAYSP-LGGKGTPWSNNA---VMDCPLL 233

Query: 817 KEIADRLGKXAAQ 855
           K+IA   GK  AQ
Sbjct: 234 KQIAMERGKTIAQ 246


>UniRef50_Q5HR31 Cluster: Oxidoreductase, aldo/keto reductase
           family; n=3; Staphylococcus|Rep: Oxidoreductase,
           aldo/keto reductase family - Staphylococcus epidermidis
           (strain ATCC 35984 / RP62A)
          Length = 279

 Score =  117 bits (281), Expect = 1e-24
 Identities = 64/175 (36%), Positives = 98/175 (56%)
 Frame = +1

Query: 127 VTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKI 306
           V  L+NG  +P +G+G +K    ++ + V+ A+D GYR    A+ YGNEK +G A+K   
Sbjct: 5   VQILNNGYPMPAVGLGVYKIADEQMEEVVRTALDAGYRAFDTAYFYGNEKALGSALK--- 61

Query: 307 QEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIF 486
               V+R++LFITSKLWN +   D        SL NL +DYLDL+LIHWP    E+D + 
Sbjct: 62  -HSNVERDELFITSKLWNDYQGYDQTIEYFNKSLDNLGLDYLDLFLIHWP---CENDQL- 116

Query: 487 PTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKP 651
                         Y++++KALE L   G ++++GV NF    L++++    + P
Sbjct: 117 --------------YIESYKALEHLYEEGKIKAIGVCNFKIHHLEKLMKETKITP 157



 Score = 39.9 bits (89), Expect = 0.18
 Identities = 13/30 (43%), Positives = 21/30 (70%)
 Frame = +2

Query: 659 NQVECHPYLNXKRLKQFCEDRDIMITXYSP 748
           NQ+E HPY N + ++ FC++ DI +T + P
Sbjct: 160 NQIELHPYFNQQDVQDFCDEHDIKVTAWMP 189


>UniRef50_Q1VRG6 Cluster: YvgN; n=1; Psychroflexus torquis ATCC
           700755|Rep: YvgN - Psychroflexus torquis ATCC 700755
          Length = 280

 Score =  117 bits (281), Expect = 1e-24
 Identities = 69/173 (39%), Positives = 103/173 (59%), Gaps = 1/173 (0%)
 Frame = +1

Query: 136 LSNGAKIPVIGIGTWKSKPGEVTQAV-KDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQE 312
           L++G +IP++G GT+K+   E  +++ K A+ +GYR I    +Y NE+ VG+AIK +   
Sbjct: 5   LNDGNRIPIVGFGTYKANEEEGIKSIQKSALTLGYRLIDTVAIYQNEEAVGKAIKAR--- 61

Query: 313 GVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPT 492
           GV+ RE++F+T+KLW         R AL+ SLR L+++Y+DLYLIHWP      +AI   
Sbjct: 62  GVL-REEIFVTTKLWRENLGYKQTRIALDESLRKLDLNYIDLYLIHWPA-----NAINYK 115

Query: 493 DADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKP 651
           D             DTW+A+E L   G ++SLGVSNF  + L+ +   A V P
Sbjct: 116 D-------WQKTNADTWRAMEELQAEGKIKSLGVSNFWPEHLEALFQTAKVSP 161


>UniRef50_Q4P4P1 Cluster: Putative uncharacterized protein; n=1;
           Ustilago maydis|Rep: Putative uncharacterized protein -
           Ustilago maydis (Smut fungus)
          Length = 322

 Score =  117 bits (281), Expect = 1e-24
 Identities = 66/173 (38%), Positives = 96/173 (55%), Gaps = 1/173 (0%)
 Frame = +1

Query: 136 LSNGAKIPVIGIGTWKS-KPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQE 312
           L+NG +IP + +G +K+   G    A K A D GYRHI  A  Y NE+ VG A+    +E
Sbjct: 21  LNNGQEIPQVALGVYKAPNDGSTENACKWAFDAGYRHIDSAARYMNEESVGRALAEWTKE 80

Query: 313 GVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPT 492
             V R ++FITSKLW+  H  D    A+E SL+ LN+DY+D+YL+H P     +  +   
Sbjct: 81  NNVPRSEIFITSKLWDADH--DKAAAAIEDSLKKLNVDYMDMYLMHSPGTMGAEKRL--- 135

Query: 493 DADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKP 651
                         + WKALE  V  G ++++GVSNF+ ++L  +L N  +KP
Sbjct: 136 --------------EAWKALEEAVDAGKIKTIGVSNFDVEELDHLLANCRIKP 174


>UniRef50_A7ALH6 Cluster: Putative uncharacterized protein; n=1;
           Parabacteroides merdae ATCC 43184|Rep: Putative
           uncharacterized protein - Parabacteroides merdae ATCC
           43184
          Length = 301

 Score =  116 bits (278), Expect = 2e-24
 Identities = 91/250 (36%), Positives = 125/250 (50%), Gaps = 2/250 (0%)
 Frame = +1

Query: 112 MTSVPVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEA 291
           M  VP   L+NG ++P +G+GT+  K     + V  AI +G+R I  A  YGNEKEVGE 
Sbjct: 26  MNKVPTVKLNNGMEMPQLGVGTFLVKDN-AAERVCHAIKVGFRLIDTAQGYGNEKEVGEG 84

Query: 292 IKTKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKE 471
           I    + G+ +RE LFIT+K+     R   VR +L+ SL +L  DY+DL LIHWP     
Sbjct: 85  I---CRSGIDRRE-LFITTKVNTMEMRGGTVRQSLDKSLADLGTDYIDLVLIHWP----- 135

Query: 472 DDAIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKP 651
                     G I+       +TW+ LE  V  G +RS+GVSNFN   L  +L+ A ++P
Sbjct: 136 --------VKGHIK-------ETWQILEEYVDKGKIRSIGVSNFNPHHLDELLEYARIRP 180

Query: 652 GH*PGRMPSVFKPXAIEAVLRRP*YYDNGVLPRWGXPDRPWAKPGD--PHLMEDPKLKEI 825
                    V     IE  + +  +   G   R G     W   G     +++DP + EI
Sbjct: 181 ---------VVNQIEIEPYMTQ--HDVVGYTFRKGIQVEAWGPLGQGVTGVLDDPAIGEI 229

Query: 826 ADRLGKXAAQ 855
           A R GK AAQ
Sbjct: 230 AARHGKSAAQ 239


>UniRef50_A5PDA8 Cluster: Putative oxidoreductase protein; n=1;
           Erythrobacter sp. SD-21|Rep: Putative oxidoreductase
           protein - Erythrobacter sp. SD-21
          Length = 272

 Score =  114 bits (275), Expect = 5e-24
 Identities = 68/180 (37%), Positives = 94/180 (52%)
 Frame = +1

Query: 112 MTSVPVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEA 291
           MT  P   L++G +IP +G GTW+ +  +  QAV  AID+GY  I  A +YGNEK VG  
Sbjct: 1   MTDYPTLNLNDGRQIPQLGFGTWQMEEEDAPQAVSTAIDVGYWLIDTAAIYGNEKGVG-- 58

Query: 292 IKTKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKE 471
                 +GV +  D+F+ +K+WN     D    A E  L  L  +++D+ LIHWP   K+
Sbjct: 59  ------KGVGEWSDIFLQTKIWNDSQGYDRTLRAAEKCLERLGREHVDMLLIHWPCPEKD 112

Query: 472 DDAIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKP 651
                              +VDTWKAL  L   G  +S+GVSNF  + L+RI+D   V P
Sbjct: 113 ------------------QFVDTWKALIELRDAGKAKSIGVSNFREEDLKRIIDETGVTP 154


>UniRef50_A2UAH0 Cluster: Aldo/keto reductase; n=1; Bacillus
           coagulans 36D1|Rep: Aldo/keto reductase - Bacillus
           coagulans 36D1
          Length = 273

 Score =  114 bits (274), Expect = 7e-24
 Identities = 66/182 (36%), Positives = 100/182 (54%), Gaps = 2/182 (1%)
 Frame = +1

Query: 112 MTSVPVT-TLSNGAKIPVIGIGTWKSKPGEVT-QAVKDAIDIGYRHIXCAFVYGNEKEVG 285
           M+S+  T  L NG  IP IG+GTW+   GE T  AV  A+  GYRHI  A+ Y NE+ VG
Sbjct: 1   MSSLHETFVLENGVAIPKIGLGTWQVPNGETTYHAVSFALKNGYRHIDTAYAYHNEESVG 60

Query: 286 EAIKTKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAY 465
           +A++    +  + R D+F+TSKL       D      + ++ N  ++ LDLYLIH P  +
Sbjct: 61  KAVR----DSGIDRRDIFVTSKLPAEIKSYDKALKTFDETMGNFGLEQLDLYLIHAPWPW 116

Query: 466 KEDDAIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASV 645
            E  A +  +            ++ WKA+E +   G  R++GVSNF+   L+ +++NA +
Sbjct: 117 SEKGADYTKEN-----------IEVWKAMEEIYESGRCRAIGVSNFSVSDLKAVMENAKI 165

Query: 646 KP 651
           KP
Sbjct: 166 KP 167


>UniRef50_Q4PHK0 Cluster: Putative uncharacterized protein; n=1;
           Ustilago maydis|Rep: Putative uncharacterized protein -
           Ustilago maydis (Smut fungus)
          Length = 355

 Score =  113 bits (272), Expect = 1e-23
 Identities = 73/201 (36%), Positives = 105/201 (52%), Gaps = 29/201 (14%)
 Frame = +1

Query: 136 LSNGAKIPVIGIGTWKSKPGEVTQAVKDAID-----------------IGYRHIX----- 249
           L+ GA+IPVIG+GTW+S PGEV +AV+ AI                  +GY  +      
Sbjct: 16  LNTGAEIPVIGLGTWQSAPGEVAKAVESAIKAGYRHIVSMLTSLLTLTLGYVALHPLYIP 75

Query: 250 -----CAFVYGNEKEVGEAIKTKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRN 414
                 A++YGNE EVG+ IK       V R +LF+T+K+W T+HR       L+ SL+ 
Sbjct: 76  FLAKDAAWIYGNENEVGQGIKAS----GVPRSELFVTTKIWCTYHRQP--EACLDESLQR 129

Query: 415 LNIDYLDLYLIHWP-QAYKEDDAIFPTDADGKIQFS-DVDYVDTWKALEPLVCHGLVRSL 588
           L +DY+DL L+HWP    K  D   P + DG      D     TW+ +E L   G  +++
Sbjct: 130 LGLDYVDLLLVHWPVPLVKRGDEKIPLNEDGSRAIDRDWSPEQTWELMEKLPATGKTKAI 189

Query: 589 GVSNFNSKQLQRILDNASVKP 651
           GVSN++   L ++L  A + P
Sbjct: 190 GVSNWSIAFLDKLLAKAKIVP 210



 Score = 37.5 bits (83), Expect = 0.97
 Identities = 15/32 (46%), Positives = 20/32 (62%)
 Frame = +2

Query: 659 NQVECHPYLNXKRLKQFCEDRDIMITXYSPXG 754
           NQVE HP+L    L ++C D+ I+   YSP G
Sbjct: 213 NQVELHPFLPQHELVKYCHDKGILPQAYSPLG 244


>UniRef50_Q28P63 Cluster: Aldo/keto reductase; n=4;
           Rhodobacteraceae|Rep: Aldo/keto reductase - Jannaschia
           sp. (strain CCS1)
          Length = 276

 Score =  112 bits (270), Expect = 2e-23
 Identities = 62/180 (34%), Positives = 98/180 (54%)
 Frame = +1

Query: 112 MTSVPVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEA 291
           MT  PV    +GA+IP +G G W+       + V+ AI+IGYR I  A++Y NE  +GE 
Sbjct: 1   MTDRPVIKFHDGAQIPQVGFGIWQVPQDIAGETVRSAIEIGYRMIDGAYLYMNEAGLGEG 60

Query: 292 IKTKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKE 471
           ++       + R+++F+T+K+WN        R ++E SL+ + ++ LDL LIHWP     
Sbjct: 61  LRA----SGLPRDEVFVTTKVWNNEQGAAKARASVERSLKTIGVEQLDLVLIHWP----- 111

Query: 472 DDAIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKP 651
                       +   D+ Y++TWKA + +   GL+RS+G SNFN+  L+RI+      P
Sbjct: 112 ------------VPSQDL-YLETWKAFQDMRDEGLMRSIGTSNFNADHLERIIAETGEAP 158


>UniRef50_Q17DN1 Cluster: Aldo-keto reductase; n=1; Aedes
           aegypti|Rep: Aldo-keto reductase - Aedes aegypti
           (Yellowfever mosquito)
          Length = 284

 Score =  112 bits (270), Expect = 2e-23
 Identities = 55/108 (50%), Positives = 77/108 (71%), Gaps = 2/108 (1%)
 Frame = +1

Query: 124 PVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTK 303
           P+  L+NG ++PV+G+GTW SK GE  +A+K AID GYRHI  A+ Y NEKEVGEAI+ K
Sbjct: 6   PMVKLNNGLEMPVLGLGTWLSKEGEGVEAIKAAIDAGYRHIDTAYFYQNEKEVGEAIRAK 65

Query: 304 IQEGVVKREDLFITSKL--WNTFHRPDLVRGALEVSLRNLNIDYLDLY 441
           I+EGVV REDLF+T+K   W+T    +L+    +  L+  ++DY+D +
Sbjct: 66  IEEGVVCREDLFVTTKFIDWDT---KNLMPYDADGKLQFSDVDYIDTW 110



 Score = 83.4 bits (197), Expect = 1e-14
 Identities = 35/57 (61%), Positives = 46/57 (80%)
 Frame = +1

Query: 481 IFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKP 651
           + P DADGK+QFSDVDY+DTWKA+E L+  G V+S+GVSNFNS+Q+ R+L    +KP
Sbjct: 90  LMPYDADGKLQFSDVDYIDTWKAMEKLLKTGKVKSIGVSNFNSEQITRLLAECEIKP 146



 Score = 50.4 bits (115), Expect = 1e-04
 Identities = 20/34 (58%), Positives = 27/34 (79%)
 Frame = +2

Query: 653 VTNQVECHPYLNXKRLKQFCEDRDIMITXYSPXG 754
           VTNQVEC+P LN ++L +FC++ DI +T YSP G
Sbjct: 147 VTNQVECNPSLNQRKLTEFCKNLDITLTAYSPLG 180


>UniRef50_Q5FT75 Cluster: Putative 2,5-diketo-D-gluconic acid
           reductase; n=1; Gluconobacter oxydans|Rep: Putative
           2,5-diketo-D-gluconic acid reductase - Gluconobacter
           oxydans (Gluconobacter suboxydans)
          Length = 279

 Score =  112 bits (269), Expect = 3e-23
 Identities = 68/175 (38%), Positives = 94/175 (53%)
 Frame = +1

Query: 127 VTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKI 306
           V +  +G  +P IG+G W++ P E  + VK+A+ +GYR +  A +Y NE+ VG+      
Sbjct: 13  VISFHDGHTMPQIGLGVWETPPDETAEVVKEAVKLGYRSVDTARLYKNEEGVGK------ 66

Query: 307 QEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIF 486
             G+    ++F+T+KLWN     D    A E S R L    LDLYLIHWP          
Sbjct: 67  --GLEDHPEIFLTTKLWNDEQGYDSTLRAYEESARLLRRPVLDLYLIHWPMP-------- 116

Query: 487 PTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKP 651
              A G+       YV+TWKAL  L   G V+S+GVSNF S+ L+RI+D   V P
Sbjct: 117 ---AQGQ-------YVETWKALVELKKSGRVKSIGVSNFESEHLERIMDATGVVP 161


>UniRef50_Q5FLI5 Cluster: Aldehyde reductase; n=2; Bacteria|Rep:
           Aldehyde reductase - Lactobacillus acidophilus
          Length = 278

 Score =  112 bits (269), Expect = 3e-23
 Identities = 81/244 (33%), Positives = 122/244 (50%), Gaps = 3/244 (1%)
 Frame = +1

Query: 133 TLSNGAKIPVIGIGTWKSKP-GEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQ 309
           TL+NG K+P +G G ++     +  Q V+D +++GYR +  A +YGNE+ VG+AIK    
Sbjct: 6   TLNNGIKMPRLGFGVYQIDDLAQAQQVVEDGLEVGYRLVDTAQIYGNEQAVGDAIK---- 61

Query: 310 EGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFP 489
              V RED+FITSK+W   +  D    A + S++ L +DY+DLYLIH P  Y        
Sbjct: 62  HSNVPREDIFITSKIWVDDYGYDNTLKAFDDSMKKLQLDYIDLYLIHKP--YN------- 112

Query: 490 TDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPGH*PGR 669
                       DY  TW+ALE L   G +R++GVS+F +++L  ++    VKP      
Sbjct: 113 ------------DYYGTWRALERLYQEGRIRAIGVSSFWNERLADLITFNDVKPA----- 155

Query: 670 MPSVFKPXAIEAVLRRP*YYDNGVLPRWGXPDRPWA--KPGDPHLMEDPKLKEIADRLGK 843
                    IE  +    +     + + G     WA    G  H+  +P L+EIA++  K
Sbjct: 156 ------VNQIETNVWNQEWKSQQYMEKEGVQPEAWAPFAEGANHIFTNPLLEEIAEKHHK 209

Query: 844 XAAQ 855
             AQ
Sbjct: 210 TTAQ 213


>UniRef50_Q24C22 Cluster: Oxidoreductase, aldo/keto reductase family
           protein; n=4; Oligohymenophorea|Rep: Oxidoreductase,
           aldo/keto reductase family protein - Tetrahymena
           thermophila SB210
          Length = 297

 Score =  111 bits (267), Expect = 5e-23
 Identities = 65/177 (36%), Positives = 93/177 (52%)
 Frame = +1

Query: 121 VPVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKT 300
           VP+     G  IP IG GT++ +  +    V +A+ IGY HI  A VY NE+++ + I  
Sbjct: 13  VPILNFREGGSIPQIGYGTYELRQNDCIIGVTEALKIGYTHIDTASVYRNEQDIAKVIHN 72

Query: 301 KIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDA 480
                 +KREDLFITSK+       +  + A++  L  LNI YLD  LIHWP   K    
Sbjct: 73  PAYG--IKREDLFITSKISPGEQGYEQAKKAVQDMLTRLNIKYLDCVLIHWPGVSK---- 126

Query: 481 IFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKP 651
             P +     Q      ++TWKAL  L   G+++ +GVSNFN   LQ +++ +  KP
Sbjct: 127 -LPPNDPKNAQIR----LETWKALIELRKAGVIKHIGVSNFNINHLQHLIEKSEFKP 178


>UniRef50_Q7NB44 Cluster: ARA1; n=3; Firmicutes|Rep: ARA1 -
           Mycoplasma gallisepticum
          Length = 289

 Score =  111 bits (266), Expect = 6e-23
 Identities = 61/173 (35%), Positives = 99/173 (57%), Gaps = 1/173 (0%)
 Frame = +1

Query: 136 LSNGAKIPVIGIGTWKSKPGEVT-QAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQE 312
           L+N  K+P IG GT+K + G+ T +AVK A+++GYRH+ CA +Y N+  V + IK     
Sbjct: 16  LANNYKMPSIGFGTYKLEDGKQTVEAVKTALEVGYRHLDCAEIYENQLSVSQGIKLS--- 72

Query: 313 GVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPT 492
             V R+++FITSK+WN     +  + A    L++L+++YLDL LIHWP      D     
Sbjct: 73  -GVNRKEIFITSKIWNDDKGYESTKKAFHKILKDLDLEYLDLLLIHWPIGKGFKD----- 126

Query: 493 DADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKP 651
                  + +V+   TWKA+E     G ++++G+SNF    ++ +  +A + P
Sbjct: 127 ------NWQEVN-AQTWKAMEEFYLEGKIKAIGLSNFLVHHIEALKKSAKILP 172


>UniRef50_Q03X85 Cluster: Aldo/keto reductase of diketogulonate
           reductase family; n=1; Leuconostoc mesenteroides subsp.
           mesenteroides ATCC 8293|Rep: Aldo/keto reductase of
           diketogulonate reductase family - Leuconostoc
           mesenteroides subsp. mesenteroides (strain ATCC 8293
           /NCDO 523)
          Length = 288

 Score =  110 bits (265), Expect = 9e-23
 Identities = 56/129 (43%), Positives = 78/129 (60%), Gaps = 2/129 (1%)
 Frame = +1

Query: 133 TLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQE 312
           TL+NGA++P +G G ++    E  QAV DAI+ GYR I  A VYGNE E G+ +   I  
Sbjct: 5   TLNNGAQMPQLGFGVFQIPAEETKQAVVDAINAGYRSIDTARVYGNEAETGQGVNEAIAN 64

Query: 313 GVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWP--QAYKEDDAIF 486
            VV RE+LF+T+KLW +    +  +GA++ SL+ L  DY DL L+H P    Y    A+ 
Sbjct: 65  AVVAREELFLTTKLWLSEFSYEAAKGAIDDSLKKLGTDYADLILLHQPYGDVYGAYKALA 124

Query: 487 PTDADGKIQ 513
              ADGK++
Sbjct: 125 EAQADGKVK 133


>UniRef50_UPI00006CCCD7 Cluster: oxidoreductase, aldo/keto reductase
           family protein; n=1; Tetrahymena thermophila SB210|Rep:
           oxidoreductase, aldo/keto reductase family protein -
           Tetrahymena thermophila SB210
          Length = 323

 Score =  110 bits (264), Expect = 1e-22
 Identities = 64/188 (34%), Positives = 102/188 (54%), Gaps = 6/188 (3%)
 Frame = +1

Query: 106 LIMTSVPVTTLSNGAKIPVIGIGTW------KSKPGEVTQAVKDAIDIGYRHIXCAFVYG 267
           +I   +    L+NG K+P++G+GT       +    E+T  + +A+D GYR+   A  Y 
Sbjct: 7   IINQDIKYVQLNNGYKMPLLGLGTQPYDIVTRVTVEEMTTLLSNALDFGYRNFDTAKQYR 66

Query: 268 NEKEVGEAIKTKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLI 447
           NE E+G+A +   Q+G  KRED+FIT+KL+  F     ++  ++ SL  L   Y+DLYLI
Sbjct: 67  NEVEIGQAFQNIFQQGKYKREDVFITTKLF-PFKIEKKIKEVVQNSLDQLQTSYIDLYLI 125

Query: 448 HWPQAYKEDDAIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRI 627
            W            T+ DG +  +     + W+ LE  V  G++RS+GV+NFN + +  +
Sbjct: 126 QW------SFTPVLTNFDGSVAVNHRPIHEVWRELEECVELGMIRSIGVANFNCQMVLDL 179

Query: 628 LDNASVKP 651
           L  A +KP
Sbjct: 180 LSYAKIKP 187


>UniRef50_Q890A0 Cluster: Oxidoreductase; n=6; Lactobacillales|Rep:
           Oxidoreductase - Lactobacillus plantarum
          Length = 282

 Score =  110 bits (264), Expect = 1e-22
 Identities = 64/173 (36%), Positives = 96/173 (55%), Gaps = 1/173 (0%)
 Frame = +1

Query: 136 LSNGAKIPVIGIGTWKSKPGEVT-QAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQE 312
           L+NG  IP +  GTW+   GE T QAV+ A+  GYRHI  A  Y NE  VG+AI+    +
Sbjct: 10  LANGVNIPKVAFGTWQIPGGEATYQAVRAALAAGYRHIDTALAYQNEASVGQAIR----D 65

Query: 313 GVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPT 492
             + RE +F+T+KL              + SL+NL +DY+DLYL+H P         +P 
Sbjct: 66  SGIPREQIFVTTKLPAETKSYQGALNDFDRSLKNLGLDYVDLYLVHAP---------WPW 116

Query: 493 DADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKP 651
              G++   D   +D W+A+E +   G  +++GVSNF  + L+ IL+ A++ P
Sbjct: 117 GQVGRVY--DEANLDVWQAMEAIYQSGRAKAIGVSNFAVRDLKNILNQATIPP 167


>UniRef50_Q1RFP0 Cluster: 2,5-diketo-D-gluconic acid reductase A;
           n=21; Bacteria|Rep: 2,5-diketo-D-gluconic acid reductase
           A - Escherichia coli (strain UTI89 / UPEC)
          Length = 294

 Score =  109 bits (262), Expect = 2e-22
 Identities = 68/180 (37%), Positives = 95/180 (52%), Gaps = 2/180 (1%)
 Frame = +1

Query: 118 SVPVTTLSNGAKIPVIGIGTWKSKPGEVT-QAVKDAIDIGYRHIXCAFVYGNEKEVGEAI 294
           +V  + LSN  K+P++G G ++    +V  Q+V +AI  GYR I  A VYGNE  VGEA+
Sbjct: 5   TVEFSVLSNNLKMPMMGFGVFQVTDKDVCKQSVLNAIRTGYRLIDTAAVYGNEDAVGEAV 64

Query: 295 KTKIQEGVVKREDLFITSKLW-NTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKE 471
           +  I EG+  RE+LFITSKLW       D+    +E SL+   ++Y DLYL+H  QA + 
Sbjct: 65  REAISEGLCTREELFITSKLWVQDMLNQDIAAAGIEASLKKSGLEYFDLYLLH--QAMR- 121

Query: 472 DDAIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKP 651
                             DY   W+ALE     G ++++GVSNF    L    +   VKP
Sbjct: 122 ------------------DYFSAWRALEDAYEEGKLKAIGVSNFYPHVLANFCETVRVKP 163


>UniRef50_Q5TNP1 Cluster: ENSANGP00000029046; n=2; Culicidae|Rep:
           ENSANGP00000029046 - Anopheles gambiae str. PEST
          Length = 331

 Score =  109 bits (261), Expect = 3e-22
 Identities = 67/168 (39%), Positives = 93/168 (55%), Gaps = 3/168 (1%)
 Frame = +1

Query: 136 LSNGAKIPVIGIGTWKSKPGEVTQAVKD-AIDIGYRHIXCAFVYGNEKEVGEAIKTKIQE 312
           L+ G  IP+ G GT++    E+   V D A++ GYRHI  A VY NE+ +G A+KT + +
Sbjct: 36  LNTGFDIPLAGFGTYQIHGQELIYQVLDYALEAGYRHIDTAVVYRNEEYIGTALKTLLPK 95

Query: 313 GVVKREDLFITSKLWNTFHRPD-LVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFP 489
             +KRED+FITSKL +   + +  V   +  SL NL  DYLDLYLIHWP    +      
Sbjct: 96  YNLKREDIFITSKLISQSGKDEAFVEQMVRKSLANLQTDYLDLYLIHWPGVSGKCGRWKW 155

Query: 490 TDADGKIQFSDVDY-VDTWKALEPLVCHGLVRSLGVSNFNSKQLQRIL 630
                     +V Y   +W AL  L   G +RS+GVSN+  K L+ +L
Sbjct: 156 LFGMQVTHPDNVKYRAASWNALSKLEREGCLRSIGVSNYTVKHLKEML 203


>UniRef50_A0JRJ6 Cluster: Aldo/keto reductase; n=2;
           Micrococcineae|Rep: Aldo/keto reductase - Arthrobacter
           sp. (strain FB24)
          Length = 281

 Score =  108 bits (260), Expect = 3e-22
 Identities = 66/178 (37%), Positives = 94/178 (52%)
 Frame = +1

Query: 118 SVPVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIK 297
           ++P  TL+NG KIP +G G ++  P E  + V+DA++ GYRHI  A  Y NE  VG AI 
Sbjct: 8   TIPQLTLNNGVKIPQLGFGVFQVPPEETQRIVEDALEAGYRHIDTAAAYRNEAGVGAAIS 67

Query: 298 TKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDD 477
                  + RED+FIT+KL N          A + S + L ++++DLYLIHW        
Sbjct: 68  A----SGIPREDIFITTKLRN--GEQGNAHEAFQNSRKALGVEFVDLYLIHW-------- 113

Query: 478 AIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKP 651
              P  + G        Y + WKA+E L  +  +R++GVSNF  + L  +L  A V P
Sbjct: 114 ---PVPSQGL-------YTEAWKAMEKLYANSQIRAIGVSNFLGEHLDTLLPAADVVP 161


>UniRef50_A0AWM8 Cluster: Aldo/keto reductase; n=4;
           Actinomycetales|Rep: Aldo/keto reductase - Arthrobacter
           sp. (strain FB24)
          Length = 287

 Score =  108 bits (259), Expect = 5e-22
 Identities = 68/179 (37%), Positives = 93/179 (51%)
 Frame = +1

Query: 115 TSVPVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAI 294
           + +P   L +G  IP +G+GTW     E   AV+ A+  GYR +  AF Y NE+ VG  I
Sbjct: 11  SDIPRLKLPHGHTIPRLGLGTWPMLEDECETAVRFALQSGYRLVDTAFQYRNEEAVGRGI 70

Query: 295 KTKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKED 474
           +T      V R +LFI+SK     H  D V+ A + SLR L +D+LD+++ HWP      
Sbjct: 71  RT----AGVPRSELFISSKFNKESHSIDGVQRAYDESLRKLGLDHLDMFMCHWP------ 120

Query: 475 DAIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKP 651
                  A GK       YVD WK L  L+  G V+++GVSNF    L+ I+D   V P
Sbjct: 121 -----VPALGK-------YVDAWKGLVKLLEEGRVKAIGVSNFKPAHLKDIIDATGVVP 167


>UniRef50_Q235V6 Cluster: Oxidoreductase, aldo/keto reductase family
           protein; n=2; Tetrahymena thermophila SB210|Rep:
           Oxidoreductase, aldo/keto reductase family protein -
           Tetrahymena thermophila SB210
          Length = 332

 Score =  107 bits (257), Expect = 8e-22
 Identities = 63/173 (36%), Positives = 99/173 (57%), Gaps = 1/173 (0%)
 Frame = +1

Query: 136 LSNGAKIPVIGIGTWK-SKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQE 312
           L+NG  +P++G+GT+  +   E+T  ++ A+D GYRHI  A  Y NE  +GE++KT  +E
Sbjct: 10  LNNGQIMPLVGLGTYLLNSKEEMTNLLRTALDAGYRHIDTAVNYQNEAMIGESLKTIFKE 69

Query: 313 GVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPT 492
           G   R+DLFI SK++   ++   +  +++ SL+ L +DY+DLY +H+P  +  +      
Sbjct: 70  GKYSRKDLFIVSKVFP--NKGINMLESVKKSLKELQLDYVDLYYLHFPLGFLSE------ 121

Query: 493 DADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKP 651
               K +F  +     W  LE     GL +S+GVSNFN   L  +L  A VKP
Sbjct: 122 ----KEEFVHLPVHVAWAQLEEAHRLGLAKSIGVSNFNVMALADLLSYAKVKP 170


>UniRef50_A2QB88 Cluster: Contig An01c0460, complete genome.
           precursor; n=1; Aspergillus niger|Rep: Contig An01c0460,
           complete genome. precursor - Aspergillus niger
          Length = 351

 Score =  107 bits (257), Expect = 8e-22
 Identities = 68/178 (38%), Positives = 100/178 (56%), Gaps = 13/178 (7%)
 Frame = +1

Query: 157 PVIGIGTWKSKPGE--VTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQEGVVKRE 330
           P +G+GT++   G   V +AV  A+  GYRHI  A  YGNE EVGEAIK    E  + RE
Sbjct: 47  PAVGLGTFQGDAGNRGVKEAVLQALRCGYRHIDTATAYGNEIEVGEAIK----ESRIPRE 102

Query: 331 DLFITSKLWNTFHRPDLVRGALEVSLRNLNIDY-LDLYLIHWPQAYKEDDAIFPTDADGK 507
           ++ +T+KL  T+HR   V  AL++SL  L ++Y L ++L +   +Y    A  P   +  
Sbjct: 103 EIIVTTKLAQTWHRVSDVERALDLSLERLQLNYGLSMHL-YSASSYSVPHAYSPGPDNNT 161

Query: 508 IQFSDV----------DYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKP 651
           I+  +           DY  TW A+E LV  G ++ +GVSNFN  +L+R+L +A + P
Sbjct: 162 IRHPNGKPIIDHELSRDYPSTWAAMESLVDKGKLKMIGVSNFNILKLERLLGSARIPP 219



 Score = 34.7 bits (76), Expect = 6.8
 Identities = 14/35 (40%), Positives = 19/35 (54%)
 Frame = +2

Query: 659 NQVECHPYLNXKRLKQFCEDRDIMITXYSPXGXLP 763
           NQ+E HPYL    L +FC+   I +  + P G  P
Sbjct: 222 NQIELHPYLPQVELVRFCKANGIHLVAHQPLGGKP 256


>UniRef50_Q8ET73 Cluster: 2,5-diketo-D-gluconate reductase; n=12;
           Bacteria|Rep: 2,5-diketo-D-gluconate reductase -
           Oceanobacillus iheyensis
          Length = 280

 Score =  107 bits (256), Expect = 1e-21
 Identities = 65/181 (35%), Positives = 90/181 (49%)
 Frame = +1

Query: 109 IMTSVPVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGE 288
           ++  +P  TL +G  IP +G GT++    +  QA+ +AID GYR I  A+ Y NE  VGE
Sbjct: 1   MVNQIPNVTLHDGLTIPKVGFGTYRLNGNDGVQAINNAIDHGYRLIDTAYNYENEGTVGE 60

Query: 289 AIKTKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYK 468
           A++         RE L ITSKL   +H  D     ++ SL   N+DY DLYLIHWP    
Sbjct: 61  AVR----RSSTPREQLLITSKLPGRYHHYDKAVTTIQESLYRANLDYYDLYLIHWPN--- 113

Query: 469 EDDAIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVK 648
                            D+ YV+ W+AL      G +RS+GV NF  + L+R+       
Sbjct: 114 --------------PIQDI-YVEAWQALIEAKRRGYIRSIGVCNFLPEHLERLKQETGEL 158

Query: 649 P 651
           P
Sbjct: 159 P 159


>UniRef50_Q043M4 Cluster: Aldo/keto reductase of diketogulonate
           reductase family; n=2; Lactobacillus|Rep: Aldo/keto
           reductase of diketogulonate reductase family -
           Lactobacillus gasseri (strain ATCC 33323 / DSM 20243)
          Length = 273

 Score =  107 bits (256), Expect = 1e-21
 Identities = 63/173 (36%), Positives = 92/173 (53%)
 Frame = +1

Query: 133 TLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQE 312
           TL+N  KIP+ G GT++  P +  QAV  A + GYR I  A  Y NE++VGEA+K     
Sbjct: 5   TLNNDVKIPIFGFGTYEISPDQTKQAVLSAFEEGYRLIDTAQYYQNEQQVGEAVKA---- 60

Query: 313 GVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPT 492
             + R+++FIT+K     +    +   L+ SLR + +DY DL LIHWP  +         
Sbjct: 61  SGLNRDEVFITTKTMTDGYEDTKI--GLDESLRRIGLDYFDLVLIHWPMGHD-------- 110

Query: 493 DADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKP 651
                        +DTW ALE     G  R++G+SNFNS+Q   ++  +SV+P
Sbjct: 111 -------------IDTWHALEAAYKAGKTRAIGISNFNSRQTLDLIHQSSVRP 150


>UniRef50_A0JX62 Cluster: 2,5-didehydrogluconate reductase; n=9;
           Bacteria|Rep: 2,5-didehydrogluconate reductase -
           Arthrobacter sp. (strain FB24)
          Length = 291

 Score =  106 bits (255), Expect = 1e-21
 Identities = 82/261 (31%), Positives = 124/261 (47%), Gaps = 13/261 (4%)
 Frame = +1

Query: 112 MTSVPVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEA 291
           M + P  +L+NG  I  +G G +K  P +    V  A++ GYRH   A +YGNE  VG+A
Sbjct: 1   MKNSPRLSLNNGVLIDQLGFGLYKVPPADAAGLVTMALEAGYRHFDTAAMYGNETGVGKA 60

Query: 292 IKTKIQ-----------EGV--VKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYL 432
           I                E    + REDLF+T+K+WN  H  D    A + S+ NL ++Y+
Sbjct: 61  IGALAGFAGGGPAGGSGEAAPSLSREDLFVTTKVWNDDHGYDATMRAFDTSMSNLGMEYV 120

Query: 433 DLYLIHWPQAYKEDDAIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSK 612
           DLYLIHWP A +    +F                ++++A+E L   G +R++GVSNF   
Sbjct: 121 DLYLIHWPCARR---GLF---------------TESYRAMETLYREGRIRAIGVSNFQPA 162

Query: 613 QLQRILDNASVKPGH*PGRMPSVFKPXAIEAVLRRP*YYDNGVLPRWGXPDRPWAKPGDP 792
            L+ +L+ A V P      +     P   +  LR+   +D     R G     W+  G  
Sbjct: 163 HLEHLLETAEVVPAVNQIEL----HPWLQQDELRQ--LHD-----RLGIRTEAWSPLGRG 211

Query: 793 HLMEDPKLKEIADRLGKXAAQ 855
            ++ DP + E+A    + AAQ
Sbjct: 212 QVLADPVVLELAAAHRRSAAQ 232


>UniRef50_Q929C8 Cluster: Lin2349 protein; n=12; Listeria|Rep:
           Lin2349 protein - Listeria innocua
          Length = 294

 Score =  106 bits (254), Expect = 2e-21
 Identities = 70/173 (40%), Positives = 93/173 (53%), Gaps = 1/173 (0%)
 Frame = +1

Query: 136 LSNGAKIPVIGIGTWKSKPGE-VTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQE 312
           L     IP IG+G ++    E +  AV+ AI++GYR    A VY NE  VG+AI     +
Sbjct: 11  LPGNETIPYIGLGVFQVTEQEFIAGAVEKAIEVGYRLFDTAAVYNNEAIVGQAIL----D 66

Query: 313 GVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPT 492
             V RE+LFI+SK+WN     D    A E +LRNL +DYLDLYLIHWP A K        
Sbjct: 67  SAVPREELFISSKVWNGDLGYDETLFAFERTLRNLKLDYLDLYLIHWPVAGK-------- 118

Query: 493 DADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKP 651
                       Y D+W+A+E L    L++S+GV+NF    L  +L  A+ KP
Sbjct: 119 ------------YRDSWRAMERLHDEKLIKSIGVANFKQHHLSDLLVAANEKP 159


>UniRef50_Q5FKI1 Cluster: Reductase-dehydrogenase; n=1;
           Lactobacillus acidophilus|Rep: Reductase-dehydrogenase -
           Lactobacillus acidophilus
          Length = 271

 Score =  106 bits (254), Expect = 2e-21
 Identities = 60/172 (34%), Positives = 94/172 (54%)
 Frame = +1

Query: 136 LSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQEG 315
           L+NG KIP I +GTW     EV + V+ A++IGYR    A  YGNE  VG+     I   
Sbjct: 9   LNNGEKIPQIQLGTWLINNDEVNKVVRQAVNIGYRGFDTAKDYGNESGVGKG----IWNS 64

Query: 316 VVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTD 495
            ++R D+F+T+KL       +  + A++ +L    ++Y+DL LIH PQ + E +      
Sbjct: 65  DIERSDIFLTTKLPTAVKDYEGTKKAIDAALDKFGLEYIDLLLIHSPQPWIEVNRTNDRH 124

Query: 496 ADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKP 651
             G +        + W+A+E  V  G VRS+GVSNF  + ++ I++N ++ P
Sbjct: 125 FKGNL--------ENWRAMEEAVKAGKVRSIGVSNFLQEDIENIVNNGTITP 168


>UniRef50_A5AD50 Cluster: Putative uncharacterized protein; n=3;
           Magnoliophyta|Rep: Putative uncharacterized protein -
           Vitis vinifera (Grape)
          Length = 304

 Score =  106 bits (254), Expect = 2e-21
 Identities = 48/76 (63%), Positives = 59/76 (77%)
 Frame = +1

Query: 136 LSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQEG 315
           L+ GAK+P +G+GTW+S PG V QAV  AI +GYRHI CA VYGNE+E+G  +K    +G
Sbjct: 10  LNTGAKMPSVGLGTWQSDPGLVGQAVAIAIKVGYRHIDCAQVYGNEEEIGIVLKKLFDDG 69

Query: 316 VVKREDLFITSKLWNT 363
           VVKREDL+ITSKLW T
Sbjct: 70  VVKREDLWITSKLWCT 85



 Score = 36.3 bits (80), Expect = 2.2
 Identities = 13/31 (41%), Positives = 19/31 (61%)
 Frame = +2

Query: 662 QVECHPYLNXKRLKQFCEDRDIMITXYSPXG 754
           QVECHP     +L  FC+ + + +T +SP G
Sbjct: 161 QVECHPSWQQSKLHAFCKSKGVHLTGFSPLG 191


>UniRef50_O13848 Cluster: NADH/NADPH dependent indole-3-acetaldehyde
           reductase AKR3C2; n=1; Schizosaccharomyces pombe|Rep:
           NADH/NADPH dependent indole-3-acetaldehyde reductase
           AKR3C2 - Schizosaccharomyces pombe (Fission yeast)
          Length = 284

 Score =  106 bits (254), Expect = 2e-21
 Identities = 75/177 (42%), Positives = 99/177 (55%), Gaps = 8/177 (4%)
 Frame = +1

Query: 145 GAKIPV--IGIGT--WKSKPGEVTQ----AVKDAIDIGYRHIXCAFVYGNEKEVGEAIKT 300
           G KIPV   G+GT  +K + GE+ +    +VK+A+  G+ HI CA VYGNE+EVG A+K 
Sbjct: 7   GPKIPVPAYGVGTALFKKEKGEINRTIVDSVKNALAAGFIHIDCAEVYGNEEEVGVALK- 65

Query: 301 KIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDA 480
              E  V R  LFITSK+    H  D +  AL  SLR L  DYLDLYL+H P  + E   
Sbjct: 66  ---EANVPRSKLFITSKV---MHNVDNIPEALNESLRKLGTDYLDLYLLHSPIPFYEK-- 117

Query: 481 IFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKP 651
                   KI  S     + WKA+E  +  GLV S+GVSNF    L+ +L  +++ P
Sbjct: 118 --------KIPIS-----EGWKAMETALGTGLVHSVGVSNFRIPDLEELLKTSTITP 161


>UniRef50_UPI00006CA3CB Cluster: oxidoreductase, aldo/keto reductase
           family protein; n=3; Tetrahymena thermophila SB210|Rep:
           oxidoreductase, aldo/keto reductase family protein -
           Tetrahymena thermophila SB210
          Length = 299

 Score =  105 bits (253), Expect = 2e-21
 Identities = 64/176 (36%), Positives = 94/176 (53%), Gaps = 1/176 (0%)
 Frame = +1

Query: 127 VTTLSNGAKIPVIGIGTWKSKP-GEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTK 303
           V TLSNG K+P  G+G+ + +   EVT  ++ A+D+GYRHI  A +Y NE+ +G A+KT 
Sbjct: 9   VITLSNGQKMPAFGLGSSRVQSVEEVTNLIRKALDVGYRHIDTAQMYENEQFIGAALKTI 68

Query: 304 IQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAI 483
             EG  KRED+F+ +K      +       ++  L+ L +DY+DL LIH P A   DD  
Sbjct: 69  FGEGKYKREDIFLVTK--QASIKGVSCLEIMKEQLQKLQVDYVDLLLIHVPLAAPSDD-- 124

Query: 484 FPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKP 651
                    Q++       W   E +   GL + LGVSNFN + +  +L    +KP
Sbjct: 125 -------YQQWNHKPVHQIWAEFEEIHSLGLAKGLGVSNFNCQMIIDLLAYCKIKP 173


>UniRef50_UPI0000DB6EE9 Cluster: PREDICTED: similar to C35D10.6;
           n=2; Endopterygota|Rep: PREDICTED: similar to C35D10.6 -
           Apis mellifera
          Length = 292

 Score =  105 bits (252), Expect = 3e-21
 Identities = 62/169 (36%), Positives = 95/169 (56%), Gaps = 2/169 (1%)
 Frame = +1

Query: 136 LSNGAKIPVIGIGTWKSKPGE-VTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQE 312
           LS+G  +P+IG GT+K +  E V Q V +++++G+R I  A  Y NE+++G A+K  + +
Sbjct: 10  LSSGYDMPLIGFGTYKIQGRELVYQVVDESLNVGFRSIDTAVGYRNEEDIGYALKNLLPK 69

Query: 313 GVVKREDLFITSKLWNTFH-RPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFP 489
             ++R D+FIT+KL  + +  P  +   ++ SL+  N  Y+DLYLIHWP A +      P
Sbjct: 70  YNLQRSDIFITTKLPPSVNGDPKGIEQCVQKSLKAFNTTYIDLYLIHWPGATR-----IP 124

Query: 490 TDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDN 636
             +             TW  L  L   G +RS+GVSNF  K LQ +L N
Sbjct: 125 ETSTNNPSLR----AKTWNKLVDLKKQGFIRSIGVSNFTIKHLQELLQN 169


>UniRef50_Q4JX70 Cluster: Putative oxidoreductase; n=1;
           Corynebacterium jeikeium K411|Rep: Putative
           oxidoreductase - Corynebacterium jeikeium (strain K411)
          Length = 285

 Score =  105 bits (252), Expect = 3e-21
 Identities = 52/134 (38%), Positives = 80/134 (59%)
 Frame = +1

Query: 118 SVPVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIK 297
           +VP   +++G   P +G+G W+    +   +V+ AI+ GYRHI  A +YGNE+ VG A+ 
Sbjct: 7   AVPTLEMNDGKTTPQLGLGVWQLSDEDTYTSVRAAIETGYRHIDTAAIYGNEEAVGRAVA 66

Query: 298 TKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDD 477
             ++ G V+RE+LFIT+KLWN        + A   S + L +DY+DLYL+HWP   + D 
Sbjct: 67  DAVKAGDVQREELFITTKLWNADQA--CGKEAFAESQKKLGMDYVDLYLLHWP-CPQADS 123

Query: 478 AIFPTDADGKIQFS 519
            +   D+  +IQ S
Sbjct: 124 FVQAYDSMAEIQQS 137


>UniRef50_P82125 Cluster: 1,5-anhydro-D-fructose reductase; n=1; Sus
           scrofa|Rep: 1,5-anhydro-D-fructose reductase - Sus
           scrofa (Pig)
          Length = 206

 Score =  105 bits (252), Expect = 3e-21
 Identities = 60/128 (46%), Positives = 73/128 (57%), Gaps = 1/128 (0%)
 Frame = +1

Query: 151 KIPVIGIGTWKSKPG-EVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQEGVVKR 327
           KIPV+G+GTW++ PG EVT+AVK AID GYRH   A++Y NE EVG  I+ KI EGVV+R
Sbjct: 1   KIPVLGLGTWQAAPGGEVTEAVKVAIDTGYRHPDSAYLYHNEDEVGVGIQAKIDEGVVRR 60

Query: 328 EDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTDADGK 507
           EDLFI SK                         YLDL  IHWP  +K  +   P D  G 
Sbjct: 61  EDLFIVSK----------------------KXXYLDLXNIHWPMQFKPGEVDLPVDRSGM 98

Query: 508 IQFSDVDY 531
           I  S+ D+
Sbjct: 99  IVASNTDF 106



 Score = 36.7 bits (81), Expect = 1.7
 Identities = 16/34 (47%), Positives = 21/34 (61%)
 Frame = +2

Query: 653 VTNQVECHPYLNXKRLKQFCEDRDIMITXYSPXG 754
           VTNQ+E HPYL  K    F + R++ +T Y P G
Sbjct: 110 VTNQIESHPYLTQK--ISFXQSRNVSVTAYRPLG 141


>UniRef50_Q17568 Cluster: Putative uncharacterized protein; n=1;
           Caenorhabditis elegans|Rep: Putative uncharacterized
           protein - Caenorhabditis elegans
          Length = 287

 Score =  105 bits (251), Expect = 4e-21
 Identities = 57/174 (32%), Positives = 101/174 (58%), Gaps = 2/174 (1%)
 Frame = +1

Query: 136 LSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQEG 315
           L NG +IP + +GT+++K  ++  AV +A+ +GYR    A  Y NEK++G A+KT +   
Sbjct: 4   LKNGQEIPKLALGTYEAKGDQLFAAVDEALKVGYRSFDTAKYYENEKDLGLALKTLLPRH 63

Query: 316 VVKREDLFITSKL--WNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFP 489
            +  ED+++TSK+  +++ +  +L+R  +  SL  L+  YLDL L+H+P+         P
Sbjct: 64  NICSEDIYLTSKVFPYSSKNAAELIRKDVNESLELLDRKYLDLVLVHYPR---------P 114

Query: 490 TDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKP 651
            D +   + + +   DTW ALE L   G +RS+GVSN+    ++ +    +++P
Sbjct: 115 LDTEDLNENNKMYRKDTWIALEKLHAEGKIRSIGVSNYEPHHIEEMRSYITIEP 168



 Score = 34.7 bits (76), Expect = 6.8
 Identities = 12/32 (37%), Positives = 19/32 (59%)
 Frame = +2

Query: 659 NQVECHPYLNXKRLKQFCEDRDIMITXYSPXG 754
           NQ+E HP+   K L+ +C   +I+   +SP G
Sbjct: 171 NQIEYHPHFQRKVLRAYCNKNEILFQAFSPLG 202


>UniRef50_Q927E1 Cluster: Lin2848 protein; n=13; Listeria|Rep:
           Lin2848 protein - Listeria innocua
          Length = 280

 Score =  104 bits (250), Expect = 6e-21
 Identities = 62/173 (35%), Positives = 96/173 (55%), Gaps = 1/173 (0%)
 Frame = +1

Query: 136 LSNGAKIPVIGIGTWK-SKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQE 312
           L+NG ++P  G G +K +    +  A++ A+D+GYR    A  Y NEKE+G+   +    
Sbjct: 11  LNNGIEMPRHGFGVYKLTDEQRMRTALETAVDVGYRLFDTASFYHNEKELGDFFASS--- 67

Query: 313 GVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPT 492
             +KR++ F+T+K+WNT    D    A E S + L +D +DLYL+HWP   K+D      
Sbjct: 68  -GLKRDEFFVTTKMWNTEQGYDETLRAFEKSQKKLQLDQVDLYLVHWP---KQD------ 117

Query: 493 DADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKP 651
                       + +TW+A+E L   GLVR++GVSNF +  L R+  +A+V P
Sbjct: 118 -----------TFFETWRAVEKLYDEGLVRAIGVSNFEAHHLDRLRTSANVLP 159


>UniRef50_Q5BLA6 Cluster: Zgc:110782; n=2; Danio rerio|Rep:
           Zgc:110782 - Danio rerio (Zebrafish) (Brachydanio rerio)
          Length = 287

 Score =  104 bits (249), Expect = 7e-21
 Identities = 62/178 (34%), Positives = 99/178 (55%), Gaps = 1/178 (0%)
 Frame = +1

Query: 121 VPVTTLSNGAKIPVIGIGTWKSKPGE-VTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIK 297
           VP   L +G ++P++G+GT+K +  E + Q+V  A+  GYR    A VYGNE  +G+ +K
Sbjct: 3   VPSVRLMSGTQMPLLGLGTYKLQDHEQLKQSVSCALQAGYRAFDTAAVYGNEAHLGQVLK 62

Query: 298 TKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDD 477
             + +  + RED+FI SKL  + H      G L  SL  L+ +Y+DLYLIHWP      +
Sbjct: 63  ELLPKYGLIREDVFIISKLAPSDHGLRAKEGCLR-SLEQLDCEYIDLYLIHWPGM----E 117

Query: 478 AIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKP 651
            + P D+    + S+     +W  LE     G  +++GVSN+ +K ++ +L +  V P
Sbjct: 118 GLDPEDS----RHSEY-RAQSWATLEEFHASGQFKAIGVSNYTAKHIRELLASCRVPP 170


>UniRef50_Q18483 Cluster: Putative uncharacterized protein; n=2;
           Caenorhabditis|Rep: Putative uncharacterized protein -
           Caenorhabditis elegans
          Length = 287

 Score =  104 bits (249), Expect = 7e-21
 Identities = 60/167 (35%), Positives = 97/167 (58%), Gaps = 1/167 (0%)
 Frame = +1

Query: 154 IPVIGIGTWKSKPGEVTQAVKDA-IDIGYRHIXCAFVYGNEKEVGEAIKTKIQEGVVKRE 330
           +P+IGIGTW+ +  E+ + V DA    GYR I  A VY NE ++G  ++  +    +KRE
Sbjct: 11  MPLIGIGTWQVQKEEILRQVIDAGFKEGYRFIDTAQVYNNEAKIGRILEKLLPANGLKRE 70

Query: 331 DLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTDADGKI 510
           D++ITSKL  +       R ++E SL NL ++YLDL LIHWP +  + +      A+ K+
Sbjct: 71  DIWITSKLAPSNAGVKKARESIEESLSNLKVEYLDLLLIHWPGSSLKSE----NPANKKL 126

Query: 511 QFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKP 651
           +      V++W  +  ++  G +RS+GVSNF    L+ +  +++V P
Sbjct: 127 R------VESWNVMCEMMAEGKLRSVGVSNFEICHLEELKKDSNVVP 167


>UniRef50_Q568D7 Cluster: Zgc:110366; n=7; Euteleostomi|Rep:
           Zgc:110366 - Danio rerio (Zebrafish) (Brachydanio rerio)
          Length = 289

 Score =  103 bits (248), Expect = 1e-20
 Identities = 65/179 (36%), Positives = 98/179 (54%), Gaps = 1/179 (0%)
 Frame = +1

Query: 118 SVPVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAI-DIGYRHIXCAFVYGNEKEVGEAI 294
           S P   L NG  IP++G+GT     G   +AV  A+ + G RHI  A  YG E+ +G+A+
Sbjct: 12  SCPAVPLHNGLNIPILGLGT-SHYGGYSHEAVLYALQECGIRHIDTAKRYGCEEALGKAV 70

Query: 295 KTKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKED 474
                E  V+RE+L++T+KLW   +     + A   S   L +DYLDLYL+HWP      
Sbjct: 71  T----ESGVQREELWVTTKLWPGDYGYQSTKQACRDSRARLGVDYLDLYLMHWP------ 120

Query: 475 DAIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKP 651
           D++ P  +  +++      ++TW+ALE L   GL R++GVSNF    L  + D+  + P
Sbjct: 121 DSMVPGRSSQEVR------LETWRALEELYDEGLCRAIGVSNFLIPHLNELKDSGGIVP 173


>UniRef50_Q7WSY4 Cluster: Putative aldo-keto reductase; n=1;
           Propionibacterium freudenreichii subsp. shermanii|Rep:
           Putative aldo-keto reductase - Propionibacterium
           freudenreichii subsp. shermanii
          Length = 280

 Score =  103 bits (247), Expect = 1e-20
 Identities = 60/172 (34%), Positives = 89/172 (51%)
 Frame = +1

Query: 115 TSVPVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAI 294
           T  P   LS G ++P++G+GTW  K  E   AV  AI+ GYR +  A  YGNE+ VG+A+
Sbjct: 6   TPTPTVELSGGTRMPMLGMGTWPLKGEECRAAVASAIEQGYRLVDTAEAYGNEEAVGKAV 65

Query: 295 KTKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKED 474
           +    E    R ++F+T+K    +H    V  ALE SL  L +DY+DL+L+HWP      
Sbjct: 66  R----EAGPDRAEIFVTTKFSKQWHSRKGVHEALEHSLERLGLDYVDLFLMHWPMP---- 117

Query: 475 DAIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRIL 630
                          +  YVD ++ +  L   GL +++GVSNF    L  ++
Sbjct: 118 --------------GEGSYVDAYRGMVELKEQGLAKAIGVSNFKVHHLDDLI 155


>UniRef50_A3VHZ9 Cluster: Oxidoreductase; n=1; Rhodobacterales
           bacterium HTCC2654|Rep: Oxidoreductase - Rhodobacterales
           bacterium HTCC2654
          Length = 278

 Score =  103 bits (247), Expect = 1e-20
 Identities = 61/160 (38%), Positives = 87/160 (54%)
 Frame = +1

Query: 124 PVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTK 303
           P  TL+NG ++P +G+GTW     E  +AV  AI+ GYR I  A  Y NE  VG+ I+  
Sbjct: 8   PTVTLANGVEMPQLGLGTWPMTDDEAAKAVATAIETGYRLIDTAENYKNETGVGQGIR-- 65

Query: 304 IQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAI 483
             +  V R+++F+T+K+   +H  D  R A E SL  L +DY+DL+LIHWP         
Sbjct: 66  --DAGVARDEVFLTTKMNKQWHSVDGARRACEASLERLGLDYIDLFLIHWPN-------- 115

Query: 484 FPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNF 603
            P             YV+ ++ L  L+  GLVR++G SNF
Sbjct: 116 -PDQG---------TYVEAFEGLTRLLDAGLVRAIGTSNF 145


>UniRef50_Q572D2 Cluster: Aldo-keto reductase, putative; n=1;
           Phytophthora infestans|Rep: Aldo-keto reductase,
           putative - Phytophthora infestans (Potato late blight
           fungus)
          Length = 255

 Score =  103 bits (247), Expect = 1e-20
 Identities = 64/179 (35%), Positives = 97/179 (54%), Gaps = 1/179 (0%)
 Frame = +1

Query: 118 SVPVTTLSNGAKIPVIGIGTWKSKPG-EVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAI 294
           +VP   L +GA+IP+IG+G ++S+PG E   A+  ++ +GYRHI  A +YGNE++VG A+
Sbjct: 4   NVPTKILPSGARIPMIGLGVYQSEPGPETYNAILTSLKLGYRHIDTAEIYGNEEDVGRAV 63

Query: 295 KTKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKED 474
           +    +  + RE++F+T+KL+ T         A + S   L I Y+ LYL+H P   KE 
Sbjct: 64  R----DSGIPREEIFVTTKLFTTNWGYSKALAAGKASNDRLGIVYIYLYLLHAPGPPKE- 118

Query: 475 DAIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKP 651
                               DTW+A+E L     +R +GVSNFN   L  +   A +KP
Sbjct: 119 ------------------RADTWRAVEDLREQETLRDIGVSNFNETLLATLRKTAHIKP 159


>UniRef50_Q88TV9 Cluster: Oxidoreductase; n=4; Lactobacillus|Rep:
           Oxidoreductase - Lactobacillus plantarum
          Length = 288

 Score =  103 bits (246), Expect = 2e-20
 Identities = 67/181 (37%), Positives = 93/181 (51%), Gaps = 1/181 (0%)
 Frame = +1

Query: 112 MTSVPVTTLSNGAKIPVIGIGTWK-SKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGE 288
           MT  P  TL++G  IP IG GT++    G   QAVK+A+ IGYRHI  A  Y NE EVG+
Sbjct: 1   MTKTPTITLNDGRAIPAIGFGTFQIPDDGSTYQAVKEALVIGYRHIDTAVAYFNEDEVGQ 60

Query: 289 AIKTKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYK 468
           AIK    +  + R+ +++TSKLW   +  D    A++ SL  L +DY+DLYLIH P    
Sbjct: 61  AIK----DSGIPRDQIWVTSKLWLQDYGFDAASRAIDRSLTKLRLDYIDLYLIHQP---- 112

Query: 469 EDDAIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVK 648
                          + DV     W+A+E     G ++S+GVSN      Q+ +      
Sbjct: 113 ---------------YGDVP--GAWQAMEAAQKAGKLKSIGVSNMTPTLWQKFVPQFETI 155

Query: 649 P 651
           P
Sbjct: 156 P 156


>UniRef50_Q3E9M9 Cluster: Uncharacterized protein At5g01670.2; n=7;
           Magnoliophyta|Rep: Uncharacterized protein At5g01670.2 -
           Arabidopsis thaliana (Mouse-ear cress)
          Length = 349

 Score =  103 bits (246), Expect = 2e-20
 Identities = 70/199 (35%), Positives = 101/199 (50%), Gaps = 27/199 (13%)
 Frame = +1

Query: 136 LSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQEG 315
           L +G KIP +G+GTW+S        V   ++ GYRHI  A+ YG+++EVG+ IK  +  G
Sbjct: 18  LLSGHKIPAVGLGTWRSGSQAAHAVVTAIVEGGYRHIDTAWEYGDQREVGQGIKRAMHAG 77

Query: 316 VVKREDLFIT----------------SKLWN-----------TFHRPDLVRGALEVSLRN 414
           + +R DLF+T                S L N           T   P+ VR AL+ +L+ 
Sbjct: 78  L-ERRDLFVTSKLWYTLILRKMINLSSPLMNVLVGTCLNKRCTELSPERVRPALQNTLKE 136

Query: 415 LNIDYLDLYLIHWPQAYKEDDAIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGV 594
           L ++YLDLYLIHWP   +E  +  P   D      D D    W+ +E L    LVR++GV
Sbjct: 137 LQLEYLDLYLIHWPIRLREGASKPPKAGD----VLDFDMEGVWREMENLSKDSLVRNIGV 192

Query: 595 SNFNSKQLQRILDNASVKP 651
            NF   +L ++L  A + P
Sbjct: 193 CNFTVTKLNKLLGFAELIP 211


>UniRef50_Q9A2X8 Cluster: Oxidoreductase, aldo/keto reductase
           family; n=3; Caulobacter|Rep: Oxidoreductase, aldo/keto
           reductase family - Caulobacter crescentus (Caulobacter
           vibrioides)
          Length = 279

 Score =  102 bits (245), Expect = 2e-20
 Identities = 62/171 (36%), Positives = 93/171 (54%), Gaps = 1/171 (0%)
 Frame = +1

Query: 112 MTSVPVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEA 291
           M+ +     S    +P +G GTW+ + G     V+ A++IGYRHI  A +YGNE++VG A
Sbjct: 1   MSKLVPAVRSGDVLMPALGFGTWQLENGTAVPLVEKALEIGYRHIDTAQIYGNERDVGAA 60

Query: 292 IKTKIQEGVVKREDLFITSKLW-NTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYK 468
           I+       VKR+++F+T+K+W + F   DL R A E SL  L +D +DL L+HWP+   
Sbjct: 61  IR----NSGVKRDEIFLTTKVWIDQFADGDLQRSA-EKSLEKLGVDQVDLLLLHWPK--- 112

Query: 469 EDDAIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQ 621
                            +V   +T KAL  +   G  R++G+SNF S QL+
Sbjct: 113 ----------------PEVPLAETLKALNAVRAKGWTRAIGLSNFPSAQLE 147



 Score = 35.9 bits (79), Expect = 3.0
 Identities = 19/43 (44%), Positives = 25/43 (58%), Gaps = 2/43 (4%)
 Frame = +2

Query: 656 TNQVECHPYLNXKRLKQFCEDRDIMITXYSP--XGXLPTDPGL 778
           T+QVE HPYL+ K LK   +   + IT +SP   G +  DP L
Sbjct: 159 TDQVEYHPYLSLKTLKAKADQLGVSITAWSPLAQGKVAQDPVL 201


>UniRef50_Q54NR2 Cluster: Aldo-keto reductase; n=3; Dictyostelium
           discoideum AX4|Rep: Aldo-keto reductase - Dictyostelium
           discoideum AX4
          Length = 305

 Score =  102 bits (244), Expect = 3e-20
 Identities = 64/178 (35%), Positives = 92/178 (51%), Gaps = 8/178 (4%)
 Frame = +1

Query: 142 NGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKI--QEG 315
           N  K+P++GIGT+K    ++   +K  ++ GYR I  A +Y NE+ +G+ +   +   +G
Sbjct: 23  NPIKMPMLGIGTFKLN--DIENIIKVGLENGYRRIDTASMYNNEERIGKVLNEMVTKNDG 80

Query: 316 V----VKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAI 483
           +    +KREDLFITSK        +    A E SL+ L +DYLD YLIHWP         
Sbjct: 81  LDGKKIKREDLFITSKCSFMEQGYENALKAFESSLKKLQLDYLDCYLIHWPGV------- 133

Query: 484 FPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILD--NASVKP 651
                DG    + +    TW+ALE L     VRS+GVSN+    L  +L   N  +KP
Sbjct: 134 --KGLDGSDSGNSIQRAQTWRALEKLYQDKKVRSIGVSNYTINHLTELLSSPNLQIKP 189


>UniRef50_A5VK30 Cluster: 2,5-didehydrogluconate reductase; n=2;
           Lactobacillus reuteri|Rep: 2,5-didehydrogluconate
           reductase - Lactobacillus reuteri F275
          Length = 300

 Score =  101 bits (243), Expect = 4e-20
 Identities = 61/177 (34%), Positives = 94/177 (53%), Gaps = 1/177 (0%)
 Frame = +1

Query: 124 PVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTK 303
           P   L+NG  IP +G+G WK+   E  Q VK+AI   Y  I  A  YGNE  VG+ I+  
Sbjct: 11  PKIKLNNGHLIPQLGLGVWKASLAETQQMVKEAIMNDYVLIDTAKQYGNEAAVGQGIQDG 70

Query: 304 IQEGVVKREDLFITSKLWNTFHRP-DLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDA 480
            +    KR+ +F+T+K++N      D +R A+   L+ L  +Y+DL L+HWP   K    
Sbjct: 71  FKATGRKRDSIFLTTKIFNGDQGDYDKLRQAVNEQLKKLQTNYVDLLLLHWPVNDK---- 126

Query: 481 IFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKP 651
                           Y ++W+ALE +   G  +++GV NFN +++  +LD+A +KP
Sbjct: 127 ----------------YNESWRALEDIYKDGQAKAIGVCNFNVERMTDLLDHAKIKP 167


>UniRef50_P47137 Cluster: Probable oxidoreductase YJR096W; n=8;
           Saccharomycetales|Rep: Probable oxidoreductase YJR096W -
           Saccharomyces cerevisiae (Baker's yeast)
          Length = 282

 Score =  101 bits (243), Expect = 4e-20
 Identities = 61/174 (35%), Positives = 95/174 (54%), Gaps = 3/174 (1%)
 Frame = +1

Query: 136 LSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQE- 312
           LSNG KIP I +GT+     +  + V + +  GYRH   A +YGNEKEVG+ I   + E 
Sbjct: 8   LSNGFKIPSIALGTYDIPRSQTAEIVYEGVKCGYRHFDTAVLYGNEKEVGDGIIKWLNED 67

Query: 313 -GVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLN-IDYLDLYLIHWPQAYKEDDAIF 486
            G  KRE++F T+KLWN+ +     + A+   L  ++ + Y+DL LIH P          
Sbjct: 68  PGNHKREEIFYTTKLWNSQNGYKRAKAAIRQCLNEVSGLQYIDLLLIHSPL--------- 118

Query: 487 PTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVK 648
                 K++      ++TW+A++  V  GLV+S+GVSN+  K +  +L+   +K
Sbjct: 119 ---EGSKLR------LETWRAMQEAVDEGLVKSIGVSNYGKKHIDELLNWPELK 163


>UniRef50_Q02198 Cluster: Morphine 6-dehydrogenase; n=5;
           Bacteria|Rep: Morphine 6-dehydrogenase - Pseudomonas
           putida
          Length = 296

 Score =  101 bits (243), Expect = 4e-20
 Identities = 76/246 (30%), Positives = 113/246 (45%), Gaps = 2/246 (0%)
 Frame = +1

Query: 124 PVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTK 303
           P+  L+NG K+P +G+G + +   E   A+  AI  GYR I  A  Y NE +VGE I+  
Sbjct: 6   PLINLNNGVKMPALGLGVFAASAEETASAIASAISSGYRLIDTARSYNNEAQVGEGIR-- 63

Query: 304 IQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAI 483
                V R ++F+T+KL+N  +  +    A + SL  L +DY+DLYL+HWP         
Sbjct: 64  --NSGVDRAEMFVTTKLFNCDYGYERALRAFDESLGRLGLDYVDLYLLHWP--------- 112

Query: 484 FPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPGH*P 663
              D +  IQ        +WKA E ++  G  R++GV NF   QL  ++  + V P    
Sbjct: 113 -TKDWNATIQ--------SWKAAEKILGDGRARAIGVCNFLEDQLDELIAASDVVPAVNQ 163

Query: 664 GRMPSVFKPXAIEAVLRRP*YYDNGVLPRWGXPDRPWA--KPGDPHLMEDPKLKEIADRL 837
             +   F    + A  R          P  G  +        G  H + DP +  IA+  
Sbjct: 164 IELHPYFAQKPLLAKNRALGIVTEAWSPIGGAINDGDGDNHGGRKHPLTDPVITTIAEAH 223

Query: 838 GKXAAQ 855
           G+ AAQ
Sbjct: 224 GRSAAQ 229


>UniRef50_P91997 Cluster: Putative uncharacterized protein; n=4;
           Caenorhabditis|Rep: Putative uncharacterized protein -
           Caenorhabditis elegans
          Length = 297

 Score =  101 bits (242), Expect = 5e-20
 Identities = 61/174 (35%), Positives = 96/174 (55%), Gaps = 2/174 (1%)
 Frame = +1

Query: 136 LSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQEG 315
           L++G  IP +G GT+K     V  A+  A+  GYR    A  Y NEKE+GEA+K  + + 
Sbjct: 15  LNSGYNIPFVGFGTYKVTGENVPPAIDAALTAGYRMFDTAKYYLNEKELGEALKILLPKH 74

Query: 316 VVKREDLFITSKLW-NTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPT 492
            + R D+F+TSK +  + +  +  RG +E SL++L  DY+D+YL+H+P+         P 
Sbjct: 75  GLSRSDVFLTSKFFPESKNCREACRGFVEESLQSLQTDYIDMYLVHYPK---------PN 125

Query: 493 DADGKIQFSDVDYVD-TWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKP 651
           D+D     ++ +Y    ++ LE     G VRS+GVSN+    L+ +   A V P
Sbjct: 126 DSDND-DVNNAEYRKIAYEVLEEAKAAGKVRSIGVSNYEIVHLEELKTYAKVPP 178


>UniRef50_A4FEB9 Cluster: 2,5-diketo-D-gluconic acid reductase; n=1;
           Saccharopolyspora erythraea NRRL 2338|Rep:
           2,5-diketo-D-gluconic acid reductase - Saccharopolyspora
           erythraea (strain NRRL 23338)
          Length = 159

 Score =  101 bits (241), Expect = 7e-20
 Identities = 52/115 (45%), Positives = 69/115 (60%)
 Frame = +1

Query: 112 MTSVPVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEA 291
           MTSVP  TL+NG ++P +G G ++    E   AV  A++ GYR I  A  YGNE  VG A
Sbjct: 1   MTSVPTVTLNNGVEMPQLGYGVFQVPEDETAAAVGAALEAGYRSIDTAAAYGNEAAVGRA 60

Query: 292 IKTKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWP 456
           +      G+  R++LF+T+KLWN     D    A + SL  L +D+LDLYLIHWP
Sbjct: 61  L---AGSGLA-RDELFVTTKLWNADQGYDNALRAFDTSLELLGLDHLDLYLIHWP 111


>UniRef50_Q5XJM7 Cluster: Zgc:101765; n=5; Eumetazoa|Rep: Zgc:101765
           - Danio rerio (Zebrafish) (Brachydanio rerio)
          Length = 288

 Score =  100 bits (239), Expect = 1e-19
 Identities = 75/247 (30%), Positives = 117/247 (47%), Gaps = 3/247 (1%)
 Frame = +1

Query: 124 PVTTLSNGAKIPVIGIGTWKSKPGEVT-QAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKT 300
           P   L+N  ++P++G+GT++ +  E T  AV  A+  GYR    A VY NE  +G A++ 
Sbjct: 6   PSVLLNNDIQMPLLGLGTFRLQGQEDTYSAVDAALKAGYRAFDTAAVYRNEAHLGHALRC 65

Query: 301 KIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWP--QAYKED 474
            + +  + RED+FITSKL     +    R   + SL  L + Y+DLYLIHWP  Q     
Sbjct: 66  LLPKHGLSREDVFITSKL-GPKDQGSKARNGCQKSLEQLGLGYIDLYLIHWPGTQGLPVG 124

Query: 475 DAIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPG 654
           D   P +              +W+ LE     G  R++GVSN+  + +Q +L +  V   
Sbjct: 125 DKRNPENR-----------AQSWRVLEEFYSEGKFRAIGVSNYTVEHMQELLKSCKVP-- 171

Query: 655 H*PGRMPSVFKPXAIEAVLRRP*YYDNGVLPRWGXPDRPWAKPGDPHLMEDPKLKEIADR 834
             P  +   F P  ++  LR       G+    G   + ++  G   L+ +P + EIA  
Sbjct: 172 --PAVLQVEFHPKLLQNDLR-------GLCKIRGVCFQAYSSLGTGLLLSNPVVLEIAKE 222

Query: 835 LGKXAAQ 855
            G+  AQ
Sbjct: 223 CGRTPAQ 229


>UniRef50_A1UEC5 Cluster: 2,5-didehydrogluconate reductase; n=20;
           Corynebacterineae|Rep: 2,5-didehydrogluconate reductase
           - Mycobacterium sp. (strain KMS)
          Length = 283

 Score =  100 bits (239), Expect = 1e-19
 Identities = 61/177 (34%), Positives = 90/177 (50%)
 Frame = +1

Query: 121 VPVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKT 300
           +P  +L++G  IPV+G+G  +    E  ++V  A++ GYR I  A VYGNE  VG A+  
Sbjct: 11  IPSVSLNDGHSIPVLGLGVGELSEAEAERSVAAALEAGYRLIDTAAVYGNEAAVGRAVNA 70

Query: 301 KIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDA 480
                 + RE++++T+KL          + A   SL  L +DY+DLYLIHW         
Sbjct: 71  ----SGIPREEIYVTTKLAVADQGFGTSQDAARASLERLGLDYVDLYLIHW--------- 117

Query: 481 IFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKP 651
             P    GK       Y+D+W  L      G+ RS+GV NFN++ L  I+D +   P
Sbjct: 118 --PAGDHGK-------YIDSWGGLMKAKQDGVARSIGVCNFNAEHLSNIIDLSFFTP 165


>UniRef50_A5BF24 Cluster: Putative uncharacterized protein; n=1;
           Vitis vinifera|Rep: Putative uncharacterized protein -
           Vitis vinifera (Grape)
          Length = 212

 Score =  100 bits (239), Expect = 1e-19
 Identities = 64/179 (35%), Positives = 98/179 (54%), Gaps = 4/179 (2%)
 Frame = +1

Query: 127 VTTLSNGAKIPVIGIGT--WKSKPGE-VTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIK 297
           +T  S G  IP++G+ T  +   P E +  ++  AI++GYRH  C   Y +EK +GEAIK
Sbjct: 1   MTLGSTGKAIPLVGMVTTVYPFAPSETMIDSILTAIELGYRHFDCVAAYLSEKPLGEAIK 60

Query: 298 TKIQEGVVK-REDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKED 474
             ++ G++K R++LFIT +             AL     NL +DYLDLYLIHW  + K  
Sbjct: 61  KAVKLGLIKSRDELFITLQ-------------AL-----NLQLDYLDLYLIHWSVSLKPG 102

Query: 475 DAIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKP 651
           +   P + D  +    +D    WKA+E      L +++GVSNF+  +L+ +L  AS+ P
Sbjct: 103 NYELPVNKDDHLP---IDLGSVWKAMEDFQKLSLTKAIGVSNFSCNKLEELLQTASILP 158


>UniRef50_A3UJS6 Cluster: Oxidoreductase; n=3;
           Alphaproteobacteria|Rep: Oxidoreductase - Oceanicaulis
           alexandrii HTCC2633
          Length = 275

 Score =   99 bits (238), Expect = 2e-19
 Identities = 60/157 (38%), Positives = 84/157 (53%)
 Frame = +1

Query: 133 TLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQE 312
           T +NGA IP +G GTW+ +  +  + V  A+  GYRHI  A +YGNE  VG+  K   Q 
Sbjct: 5   TQANGADIPKLGFGTWQLEDEDAARGVATALKTGYRHIDTAQIYGNEAAVGDGWK---QS 61

Query: 313 GVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPT 492
           G VKRED F+T+K+W    R   ++ +++ SL  L  DY+DL L+HWP            
Sbjct: 62  G-VKREDFFLTTKVWRDKFRDGDLQASVKESLDKLKTDYVDLLLLHWP------------ 108

Query: 493 DADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNF 603
                    +V   +T KA+  +   G VR +GVSNF
Sbjct: 109 -------VPEVPIAETMKAMNEVKEAGQVRHIGVSNF 138


>UniRef50_Q6CEJ0 Cluster: Yarrowia lipolytica chromosome B of strain
           CLIB122 of Yarrowia lipolytica; n=1; Yarrowia
           lipolytica|Rep: Yarrowia lipolytica chromosome B of
           strain CLIB122 of Yarrowia lipolytica - Yarrowia
           lipolytica (Candida lipolytica)
          Length = 302

 Score =   99 bits (238), Expect = 2e-19
 Identities = 70/186 (37%), Positives = 95/186 (51%), Gaps = 8/186 (4%)
 Frame = +1

Query: 118 SVPVTTLSNGAKIPVIGIGT---WKSKPGE-----VTQAVKDAIDIGYRHIXCAFVYGNE 273
           +VP   LSNG +IP IG G+   WK  PGE     +  AV  AI+ G+ HI  A  YG E
Sbjct: 2   TVPKVKLSNGLEIPAIGFGSGTKWKRPPGEKEERELIDAVVSAINAGHLHIDTAEFYGTE 61

Query: 274 KEVGEAIKTKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHW 453
           K++GEAIK    E  V R+D+F+TSK        D +  ++   L+ L  DY DL+LIH 
Sbjct: 62  KQIGEAIK----ESGVPRKDIFLTSKTLFGLLADDPIE-SISNQLKTLQTDYFDLFLIHV 116

Query: 454 PQAYKEDDAIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILD 633
           P     DD              + D    W  LE L   GL +++GVSN +  +L+ I+ 
Sbjct: 117 P---PNDDI-------------NYDLAKAWGVLEQLYEKGLAKAIGVSNHSPAELETIIK 160

Query: 634 NASVKP 651
            A +KP
Sbjct: 161 VAKIKP 166


>UniRef50_Q7VHE1 Cluster: Putative uncharacterized protein; n=1;
           Helicobacter hepaticus|Rep: Putative uncharacterized
           protein - Helicobacter hepaticus
          Length = 270

 Score = 99.1 bits (236), Expect = 3e-19
 Identities = 70/241 (29%), Positives = 118/241 (48%)
 Frame = +1

Query: 133 TLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQE 312
           TL+NG K+P++G+GT+        +A+ +AI++GYR    A +Y NE E+G AI   ++ 
Sbjct: 5   TLNNGVKMPILGLGTYSLTGKAGQKAMSEAIEVGYRLFDSAQMYNNEAELGAAINAAVKG 64

Query: 313 GVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPT 492
           G +KRE+ FI +KL  +    DL + ++E SL+ L +DY+D  LIH P  Y +  A++  
Sbjct: 65  G-IKREEFFIQTKLLES-SSEDLAKKSIEKSLKTLGLDYIDSLLIHMP--YSQSKAMY-- 118

Query: 493 DADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPGH*PGRM 672
                            +A+E     G++R +G+SNF +K     + +  V P       
Sbjct: 119 -----------------RAMESFYKQGILRVIGISNFGAKAYSEFVKSCEVIPAINQCET 161

Query: 673 PSVFKPXAIEAVLRRP*YYDNGVLPRWGXPDRPWAKPGDPHLMEDPKLKEIADRLGKXAA 852
             + +   +   ++        +L  W     P+   G   ++E+P LK IA +  K  A
Sbjct: 162 HLLLQQKPLREAMKS----KKTLLQSWS----PFI-AGKGSILENPTLKSIAQKYNKTPA 212

Query: 853 Q 855
           Q
Sbjct: 213 Q 213


>UniRef50_Q0SFM4 Cluster: Probable 2,5-didehydrogluconate reductase;
           n=1; Rhodococcus sp. RHA1|Rep: Probable
           2,5-didehydrogluconate reductase - Rhodococcus sp.
           (strain RHA1)
          Length = 265

 Score = 99.1 bits (236), Expect = 3e-19
 Identities = 78/234 (33%), Positives = 113/234 (48%)
 Frame = +1

Query: 154 IPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQEGVVKRED 333
           IP +G+GTW     + T+AV   I+ GYR I  A +Y NE  VG A+     E  V RE+
Sbjct: 4   IPPLGLGTWPLTGPDATRAVLSGIEAGYRLIDTATIYDNEDAVGVALA----ECGVPREE 59

Query: 334 LFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTDADGKIQ 513
           LF+T+KL  + H    +RGA+E SL+NL +D LDL+LIHWP                   
Sbjct: 60  LFVTTKLRGSDHVSGDIRGAVERSLKNLGLDRLDLFLIHWPLPRHN-------------- 105

Query: 514 FSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPGH*PGRMPSVFKPX 693
                YV  ++A+      GLVR +GVSNF    L+R++           G  P+V +  
Sbjct: 106 ----RYVAAFEAMLACRDAGLVRHVGVSNFLETHLRRVVAET--------GESPAVNQIQ 153

Query: 694 AIEAVLRRP*YYDNGVLPRWGXPDRPWAKPGDPHLMEDPKLKEIADRLGKXAAQ 855
              ++ R P    +  L   G   + W+  G   ++  P + +IA RL +  AQ
Sbjct: 154 MDPSLARLPVRRADDEL---GVSTQSWSPLGRGEVLGSPVVTDIARRLDRTPAQ 204


>UniRef50_A6RMS0 Cluster: Putative uncharacterized protein; n=1;
           Botryotinia fuckeliana B05.10|Rep: Putative
           uncharacterized protein - Botryotinia fuckeliana B05.10
          Length = 286

 Score = 97.9 bits (233), Expect = 6e-19
 Identities = 79/243 (32%), Positives = 119/243 (48%), Gaps = 3/243 (1%)
 Frame = +1

Query: 136 LSNGAKIPVIGIGTWKSKPG--EVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQ 309
           L NG+ +P IG+GT++   G  +V   VK AI  GYRHI  A  YGNE+ +G+AIK    
Sbjct: 10  LVNGSTLPAIGLGTFQGDDGNEKVKNIVKAAIQAGYRHIDGAAAYGNEEAIGDAIK---- 65

Query: 310 EGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFP 489
           E  + R++L   ++ W   H P  V  AL++SL  L ++Y+       P AY       P
Sbjct: 66  ESGISRDEL---AQPW---HEPKDVERALDLSLEALGLEYV-------PHAYLPG----P 108

Query: 490 TDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPGH*PGR 669
            + D +       Y +TW+A+E LV  G  +++G+SNFN  + +RIL+ A ++P      
Sbjct: 109 NNVDYE---RSRKYTETWQAMEKLVDSGKAKAIGLSNFNILKTKRILEIARIRPAVNQVE 165

Query: 670 MPSVFKPXAIEAVLRRP*YYDNGVLPRWGXPDRPWAKPGD-PHLMEDPKLKEIADRLGKX 846
               F    + A   +   +     P  G P    A   D P  + D K+ +IA + G  
Sbjct: 166 AHPYFPQHELLAFCEKEHIHLMAHQPLGGKPVGVVAPHADIPGPLFDTKIAQIAAQTGMT 225

Query: 847 AAQ 855
            AQ
Sbjct: 226 PAQ 228


>UniRef50_Q4WP69 Cluster: Aldehyde reductase, putative; n=1;
           Aspergillus fumigatus|Rep: Aldehyde reductase, putative
           - Aspergillus fumigatus (Sartorya fumigata)
          Length = 350

 Score = 97.5 bits (232), Expect = 9e-19
 Identities = 62/148 (41%), Positives = 84/148 (56%), Gaps = 7/148 (4%)
 Frame = +1

Query: 229 IGYRHIXCAFVYGNEKEVGEAIKTKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSL 408
           +GYRHI  A V  NE EVG   K K+    V RE +F+TSKLWNT H P  V  AL+ ++
Sbjct: 72  VGYRHIDSAAVGLNEAEVGRGWK-KLG---VPREGIFLTSKLWNTHHHPSHVEEALDKTV 127

Query: 409 RNLNIDYLDLYLI----HWPQAYKEDDAIFPTDADGKIQFS--DVDYVDTWKALEPLVCH 570
           ++L  +YLDLYL+    H    Y+      P    G  +F   D+   DTW A E LV  
Sbjct: 128 KDLQTNYLDLYLLYPLGHILHTYQRH---IPASRPGHKRFRLVDIPIGDTWAAREKLVNA 184

Query: 571 GLVRSLGVSN-FNSKQLQRILDNASVKP 651
           G +RSLGVSN F  ++++ +L+ A + P
Sbjct: 185 GKIRSLGVSNLFTIEKMEELLNTADIPP 212


>UniRef50_Q0CK00 Cluster: Predicted protein; n=1; Aspergillus
           terreus NIH2624|Rep: Predicted protein - Aspergillus
           terreus (strain NIH 2624)
          Length = 292

 Score = 97.5 bits (232), Expect = 9e-19
 Identities = 69/185 (37%), Positives = 96/185 (51%), Gaps = 9/185 (4%)
 Frame = +1

Query: 124 PVTTLSNGAKIPVIGIGT----WKSKPGEVT-----QAVKDAIDIGYRHIXCAFVYGNEK 276
           P  +L +G  +P++G GT    +K  P + T     + +K A++ G+ HI  A  YG E+
Sbjct: 4   PALSLKDGNLVPILGFGTGTAWYKDDPNDPTNPELIEVLKAALEKGFHHIDAADSYGTER 63

Query: 277 EVGEAIKTKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWP 456
           EVG AI+    E  + RE LFIT+K+   +     V GAL+ SL  L +DY+DLYL+H P
Sbjct: 64  EVGIAIR----ESGIPREQLFITTKVLEGWKD---VPGALDASLERLQLDYVDLYLLHNP 116

Query: 457 QAYKEDDAIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDN 636
                   + P   D  IQ         WK LE +   G  RS+GVSNF    L+ IL+ 
Sbjct: 117 Y-------VIPNLTD--IQ-------SAWKGLEAVKATGKARSIGVSNFQRNHLEAILET 160

Query: 637 ASVKP 651
            SV P
Sbjct: 161 CSVVP 165


>UniRef50_Q8G7K9 Cluster: Dehydrogenase or reductase protein; n=4;
           Bifidobacterium|Rep: Dehydrogenase or reductase protein
           - Bifidobacterium longum
          Length = 289

 Score = 97.1 bits (231), Expect = 1e-18
 Identities = 60/178 (33%), Positives = 86/178 (48%)
 Frame = +1

Query: 118 SVPVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIK 297
           +VP   L +G  IP +G+G  +     V   V+ A++ GYRHI  A  Y NE  VG A+ 
Sbjct: 10  NVPDIALKDGHSIPQVGLGVLRIDDEGVVPVVESALEAGYRHIDGAAGYNNEAGVGRALA 69

Query: 298 TKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDD 477
                   KRE L++T+KL ++    D    A + SL+ L +DY+D+Y+IHWP  +    
Sbjct: 70  ASGYNKGAKRETLWVTTKLRDSQQGYDSALKAFDNSLKLLQLDYVDMYMIHWPTPF---- 125

Query: 478 AIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKP 651
                         D    DTWKA   L   G+ R+LGV NF    L+R+ +     P
Sbjct: 126 --------------DWRSTDTWKAFVKLRDEGMARTLGVCNFMPADLKRLHEETGAWP 169


>UniRef50_A6VNW9 Cluster: Aldo/keto reductase precursor; n=1;
           Actinobacillus succinogenes 130Z|Rep: Aldo/keto
           reductase precursor - Actinobacillus succinogenes 130Z
          Length = 315

 Score = 97.1 bits (231), Expect = 1e-18
 Identities = 68/240 (28%), Positives = 113/240 (47%)
 Frame = +1

Query: 136 LSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQEG 315
           L+NG ++P+IGIG W   P +  ++V +A+  GYR I  A +Y NE+ VG A++    + 
Sbjct: 47  LNNGIEMPIIGIGVWTLTPEQTEKSVGEALKAGYRLIDTARMYRNEQAVGRAVR----DS 102

Query: 316 VVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTD 495
            + RE++FIT+K++ +    +    A+   LR L+ DY+DL L+H+P             
Sbjct: 103 GIPREEIFITTKIYGSGDYAN-AEAAINERLRLLDTDYIDLLLLHYP------------- 148

Query: 496 ADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPGH*PGRMP 675
                   D +    WK +E  V  G +R++G+SN++ K   RI+  A++ P      + 
Sbjct: 149 --------DQNDTKAWKVMEQFVKAGKIRAIGLSNYHRKTFNRIMQAATITPAVVQNEVH 200

Query: 676 SVFKPXAIEAVLRRP*YYDNGVLPRWGXPDRPWAKPGDPHLMEDPKLKEIADRLGKXAAQ 855
              +    +A LR          P  G     +   G   L  DP +  +A +  K  AQ
Sbjct: 201 IYNQDKQTKAFLRNYGTQMEAWYPLGGR--NSYGNGGKDVLFADPTIVSLAKKYAKSPAQ 258


>UniRef50_Q89JN4 Cluster: Oxidoreductase; n=8; Rhizobiales|Rep:
           Oxidoreductase - Bradyrhizobium japonicum
          Length = 272

 Score = 96.7 bits (230), Expect = 1e-18
 Identities = 42/109 (38%), Positives = 70/109 (64%)
 Frame = +1

Query: 139 SNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQEGV 318
           +NGA+IP IG+GTW+       + V+ A+ +GYRHI  A VY NE+EVG+ ++       
Sbjct: 6   ANGARIPAIGLGTWELSGRPCARVVEQALRLGYRHIDTAQVYDNEREVGDGVRA----SG 61

Query: 319 VKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAY 465
           V+R+D+F+T+K+W     P+ +  +++ SL  L +  +DL L+HWP ++
Sbjct: 62  VRRDDVFLTTKVWTNHFAPNDLERSVKESLARLRLPSVDLLLLHWPNSH 110



 Score = 37.5 bits (83), Expect = 0.97
 Identities = 17/45 (37%), Positives = 26/45 (57%), Gaps = 2/45 (4%)
 Frame = +2

Query: 653 VTNQVECHPYLNXKRLKQFCEDRDIMITXYSP--XGXLPTDPGLS 781
           V NQVE HPYL+  +++  C+   + +  YSP   G + TD  L+
Sbjct: 154 VCNQVEFHPYLDQAKVRAACDQHGLALVAYSPIARGRIKTDQTLA 198


>UniRef50_A7RRF6 Cluster: Predicted protein; n=2; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 275

 Score = 96.3 bits (229), Expect = 2e-18
 Identities = 64/180 (35%), Positives = 93/180 (51%)
 Frame = +1

Query: 112 MTSVPVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEA 291
           +T     TLS+G KIP  G+G +        QAV  A++ GYR I  A  Y NEK VGEA
Sbjct: 1   LTLSSTRTLSDGYKIPRFGLGLYDLDEKHTKQAVLWALENGYRMIDTAASYNNEKRVGEA 60

Query: 292 IKTKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKE 471
           ++    E  V R ++++ +K+++T H  +    A + SL  L +DY+DLYLIH       
Sbjct: 61  LR----ESAVPRSEVYLVTKVYHTDHGYEKTMKAYDRSLSALGVDYVDLYLIH------- 109

Query: 472 DDAIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKP 651
               FP  A           V +W+A+  L   GL RS+GVSNFN   L+ +  ++ + P
Sbjct: 110 ----FPVPA---------GVVGSWEAMAELQGKGLTRSIGVSNFNIHHLEALQKHSVIPP 156



 Score = 39.1 bits (87), Expect = 0.32
 Identities = 16/32 (50%), Positives = 18/32 (56%)
 Frame = +2

Query: 653 VTNQVECHPYLNXKRLKQFCEDRDIMITXYSP 748
           V NQ+E HPYL  + L  FC    I I  YSP
Sbjct: 157 VVNQIEVHPYLQMEELVDFCRKHSIAIQAYSP 188


>UniRef50_Q6F7K7 Cluster: 2,5-diketo-D-gluconate reductase; n=20;
           Bacteria|Rep: 2,5-diketo-D-gluconate reductase -
           Acinetobacter sp. (strain ADP1)
          Length = 297

 Score = 95.9 bits (228), Expect = 3e-18
 Identities = 63/181 (34%), Positives = 90/181 (49%)
 Frame = +1

Query: 109 IMTSVPVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGE 288
           I  ++P   L +G  IP +G GT+  K  +    +  A+  GYR +  AF Y NE  VG 
Sbjct: 18  IEKNIPDLILHDGHSIPALGFGTYTLKGQQGVDTMLRALGHGYRMLDSAFNYENEGAVGA 77

Query: 289 AIKTKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYK 468
           A++   Q G++ R+++FITSKL    H  D     +E SL  +  DYLDLYLIHWP   +
Sbjct: 78  AVR---QSGLL-RDEIFITSKLPGRHHAYDKAMETIEESLYRMQFDYLDLYLIHWPNPQQ 133

Query: 469 EDDAIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVK 648
                      G        Y++ W+AL      G +RS+GVSNF  K ++ +     V 
Sbjct: 134 -----------GL-------YIEAWQALIDAQKKGYIRSIGVSNFLPKHIETLRRETGVI 175

Query: 649 P 651
           P
Sbjct: 176 P 176


>UniRef50_Q9C1X5 Cluster: Xylose and arabinose reductase; n=1;
           Schizosaccharomyces pombe|Rep: Xylose and arabinose
           reductase - Schizosaccharomyces pombe (Fission yeast)
          Length = 283

 Score = 95.9 bits (228), Expect = 3e-18
 Identities = 68/171 (39%), Positives = 87/171 (50%)
 Frame = +1

Query: 115 TSVPVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAI 294
           T     TL+NG  IP IG G +  K  E    V  A+D GYRHI  A VYGNE   G+AI
Sbjct: 6   TESTTVTLTNGMVIPRIGFGAFMLKYNECYGLVTQALDSGYRHIDTAAVYGNEDICGKAI 65

Query: 295 KTKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKED 474
               ++  VKR D+F+TSKL N        R A+  SL +L   Y+DL+LI  P      
Sbjct: 66  VDWCEKNNVKRTDIFLTSKLANCSDYYS-TRAAIRSSLHHLG-TYIDLFLIQSP------ 117

Query: 475 DAIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRI 627
                  A GK        + +WKA+E  V  G +RS+GVSN+  K LQ +
Sbjct: 118 -------AGGK-----KSRIASWKAMEEFVDSGDIRSVGVSNYGVKHLQEL 156



 Score = 36.7 bits (81), Expect = 1.7
 Identities = 13/30 (43%), Positives = 20/30 (66%)
 Frame = +2

Query: 659 NQVECHPYLNXKRLKQFCEDRDIMITXYSP 748
           NQ+E HP+L+   + ++C+  DI I  YSP
Sbjct: 168 NQIELHPFLSQDDIVKYCQSHDIAIEAYSP 197


>UniRef50_Q2U219 Cluster: Aldo/keto reductase family proteins; n=6;
           Pezizomycotina|Rep: Aldo/keto reductase family proteins
           - Aspergillus oryzae
          Length = 294

 Score = 95.9 bits (228), Expect = 3e-18
 Identities = 64/187 (34%), Positives = 99/187 (52%), Gaps = 9/187 (4%)
 Frame = +1

Query: 118 SVPVTTLSNGAKIPVIGIGT---WKSKPG------EVTQAVKDAIDIGYRHIXCAFVYGN 270
           + P   L++   IP++G GT   W  + G      E+ +A+K AI +GYRH+  A VYG 
Sbjct: 8   NTPRVKLNDNVSIPILGYGTGTAWYKQAGDDSVNRELVEAIKTAIRLGYRHLDGAEVYGT 67

Query: 271 EKEVGEAIKTKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIH 450
           E E+G AIK    E  + RE+LF+T+K+         +  A++ SLR L ++Y+DLYLIH
Sbjct: 68  EAELGVAIK----ESGIPREELFVTTKVITNIAD---IPSAIDQSLRKLQLNYVDLYLIH 120

Query: 451 WPQAYKEDDAIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRIL 630
            P         F   +DG++Q         W A+E +   G  +++GVSN++   L+  L
Sbjct: 121 SP---------FFAKSDGELQ-------QAWAAMEKVQQAGKAKAIGVSNYHQSHLEATL 164

Query: 631 DNASVKP 651
             A + P
Sbjct: 165 KTAVIAP 171



 Score = 38.7 bits (86), Expect = 0.42
 Identities = 17/41 (41%), Positives = 23/41 (56%)
 Frame = +2

Query: 653 VTNQVECHPYLNXKRLKQFCEDRDIMITXYSPXGXLPTDPG 775
           V NQ+E HPYL  + L +F  ++DI I  Y P   +   PG
Sbjct: 172 VINQIEHHPYLQQEELLRFQREKDIKIASYGPLTPILRAPG 212


>UniRef50_Q15NA5 Cluster: Aldo/keto reductase; n=2;
           Gammaproteobacteria|Rep: Aldo/keto reductase -
           Pseudoalteromonas atlantica (strain T6c / BAA-1087)
          Length = 273

 Score = 95.5 bits (227), Expect = 3e-18
 Identities = 60/159 (37%), Positives = 83/159 (52%)
 Frame = +1

Query: 154 IPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQEGVVKRED 333
           IP  G GT++ K  +   AV++A+D+GYRHI  A  Y NE EVG+AI        + R +
Sbjct: 11  IPTPGFGTYRLKGDDAKLAVENALDVGYRHIDTAQAYENEAEVGDAISA----SKISRGE 66

Query: 334 LFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTDADGKIQ 513
           LF+T+K+W      D    +++ SL  LN DY+DL L+HWP              D K+ 
Sbjct: 67  LFVTTKVWFDNLSADKFITSVQNSLTQLNTDYVDLLLVHWP------------SPDNKV- 113

Query: 514 FSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRIL 630
            S  +Y+   KA +     GL R +GVSNF   QL   L
Sbjct: 114 -SMAEYLKELKACKE---RGLTRHIGVSNFTQSQLDEAL 148



 Score = 37.9 bits (84), Expect = 0.73
 Identities = 14/34 (41%), Positives = 20/34 (58%)
 Frame = +2

Query: 653 VTNQVECHPYLNXKRLKQFCEDRDIMITXYSPXG 754
           +TNQ+E HP    K L  +C+  +I +T Y P G
Sbjct: 157 LTNQIEVHPNFQNKELVAYCQRNNIQVTAYMPLG 190


>UniRef50_Q8Y463 Cluster: Lmo2592 protein; n=40; Bacteria|Rep:
           Lmo2592 protein - Listeria monocytogenes
          Length = 283

 Score = 95.1 bits (226), Expect = 5e-18
 Identities = 78/241 (32%), Positives = 117/241 (48%), Gaps = 1/241 (0%)
 Frame = +1

Query: 136 LSNGAKIPVIGIGTWK-SKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQE 312
           L+NG ++P++G GT++ +   E   AVKDAI  GYRHI  A  Y NE+ VG  I      
Sbjct: 6   LNNGVEVPILGFGTYQITDAAEAEHAVKDAIKAGYRHIDTAQSYMNEEAVGRGIAA---- 61

Query: 313 GVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPT 492
             V R++LFIT+K+W        V  + + SL+ L +DY+DL LIH P            
Sbjct: 62  SGVDRKELFITTKIWVENVSYKGVMSSFDRSLKRLGLDYVDLLLIHQP------------ 109

Query: 493 DADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPGH*PGRM 672
                  F+DV     W A+E L   G +R++GVSNF+  ++  +     V P      +
Sbjct: 110 -------FNDV--YGAWIAMEELQASGKIRAIGVSNFSPDRVIDLAAFNEVTPQVNQIEV 160

Query: 673 PSVFKPXAIEAVLRRP*YYDNGVLPRWGXPDRPWAKPGDPHLMEDPKLKEIADRLGKXAA 852
               +  A  A+LR+    +   +  W     P+A+ G   +  +P L +I  + GK AA
Sbjct: 161 NPFQQQTANLAILRK----EGVAIEAWA----PFAE-GKNDIFNNPVLTKIGAKYGKSAA 211

Query: 853 Q 855
           Q
Sbjct: 212 Q 212


>UniRef50_Q8EUH6 Cluster: Oxidoreductase; n=1; Mycoplasma
           penetrans|Rep: Oxidoreductase - Mycoplasma penetrans
          Length = 285

 Score = 94.7 bits (225), Expect = 6e-18
 Identities = 62/173 (35%), Positives = 92/173 (53%), Gaps = 1/173 (0%)
 Frame = +1

Query: 136 LSNGAKIPVIGIGTWKSKPGEVTQAVKDAID-IGYRHIXCAFVYGNEKEVGEAIKTKIQE 312
           L+NG  +P+IG+G +K++       +  AID  GYR I  A VY NE+ VG AIK    +
Sbjct: 6   LANGLHMPIIGLGVYKAEGENCENTIIKAIDDYGYRMIDTAQVYFNEEFVGNAIK----Q 61

Query: 313 GVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPT 492
             +KRED+FIT+K+W + +  +    ++  SL+ L  +Y+DL L+H P            
Sbjct: 62  TKIKREDIFITTKVWISNYGYNNTMYSISKSLKKLQTNYIDLVLLHQPFG---------- 111

Query: 493 DADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKP 651
                      DY   WKALE L   G+V+++GVSNF + +L     +  VKP
Sbjct: 112 -----------DYYSAWKALEVLYKKGIVKAIGVSNFEADRLVDFCLHVDVKP 153


>UniRef50_A4YQ04 Cluster: 2,5-diketo-D-gluconate reductase B; n=15;
           Proteobacteria|Rep: 2,5-diketo-D-gluconate reductase B -
           Bradyrhizobium sp. (strain ORS278)
          Length = 273

 Score = 94.7 bits (225), Expect = 6e-18
 Identities = 42/106 (39%), Positives = 66/106 (62%)
 Frame = +1

Query: 139 SNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQEGV 318
           + G ++P +G+GT++ +      AV+ A+ +GYRHI  A +Y NE  +G A+        
Sbjct: 6   TQGVRLPKLGLGTFRMQGTVCRDAVESALALGYRHIDTAEMYANEDAIGAALAA----AQ 61

Query: 319 VKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWP 456
           + REDL +T+K+W     PD +R A + SL+ L +D++DLYLIHWP
Sbjct: 62  IAREDLHVTTKVWPENLAPDAIRRAFDTSLKKLRLDFVDLYLIHWP 107


>UniRef50_Q1DLF1 Cluster: Putative uncharacterized protein; n=1;
           Coccidioides immitis|Rep: Putative uncharacterized
           protein - Coccidioides immitis
          Length = 324

 Score = 94.7 bits (225), Expect = 6e-18
 Identities = 65/177 (36%), Positives = 94/177 (53%), Gaps = 10/177 (5%)
 Frame = +1

Query: 151 KIPVIGIGTWKSKP-----GEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQEG 315
           +IP  G+GT++  P     G V  +V  A+ IGYRHI  A  YG    V   I   I+  
Sbjct: 15  RIPARGLGTFQVDPSLYPEGSVKDSVLHALKIGYRHIDAALAYG-WGSVERGIGAAIRAS 73

Query: 316 VVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAY-KEDDAIFPT 492
            V RED+F+ +KL N FH P+ V   + +SL+NL + Y+       P AY K ++     
Sbjct: 74  GVPREDVFVVTKLHNCFHAPEDVEVGMNMSLKNLGLGYV-------PYAYTKGENYSTVR 126

Query: 493 DADGK----IQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKP 651
             DGK    I+ S   +  TWKA+E LV  G  + +GVSNF++ +L+R+L    + P
Sbjct: 127 KPDGKPVVDIELSRA-FDTTWKAMENLVDQGKAKLIGVSNFSTPKLKRLLSVCRIFP 182



 Score = 42.7 bits (96), Expect = 0.026
 Identities = 17/37 (45%), Positives = 23/37 (62%)
 Frame = +2

Query: 653 VTNQVECHPYLNXKRLKQFCEDRDIMITXYSPXGXLP 763
           V NQVE +PY   K+L +FC + +I +T Y P G  P
Sbjct: 183 VVNQVELNPYFPQKQLLRFCHEHEIHVTAYGPLGCTP 219


>UniRef50_A7D761 Cluster: Aldo/keto reductase; n=2;
           Halobacteriaceae|Rep: Aldo/keto reductase - Halorubrum
           lacusprofundi ATCC 49239
          Length = 665

 Score = 94.3 bits (224), Expect = 8e-18
 Identities = 56/185 (30%), Positives = 85/185 (45%), Gaps = 18/185 (9%)
 Frame = +1

Query: 151 KIPVIGIGTWKSKPGEVTQAVKD---AIDIGYRHIXCAFVYGNEKEVGEAIKTKIQEGVV 321
           ++P +G G  + + GE    V     A+D GYR +  A +YGNE  +GE +      G  
Sbjct: 375 RLPAVGFGCSRYRDGEYVDRVDSIATALDAGYRLLDSAELYGNEHRIGELLAAP---GAP 431

Query: 322 KREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAY------------ 465
            RE +F+  K W T HR + +  A   S   L ID  D Y +HWP A             
Sbjct: 432 DRERVFLLGKAWRTNHRREHLLAACAGSREELGIDAFDCYALHWPSALEHRGELNRLAEK 491

Query: 466 ---KEDDAIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDN 636
              +++   FP   DG+   +DV     W+ LE +   G  R+LG+ N +  QL+ +L+ 
Sbjct: 492 PVERQETLTFPEGEDGEPATADVALATAWRNLEAVHERGWARTLGICNVSRAQLETVLET 551

Query: 637 ASVKP 651
             + P
Sbjct: 552 GEIDP 556


>UniRef50_A3JU52 Cluster: 2,5-diketo-D-gluconic acid reductase A;
           n=1; Rhodobacterales bacterium HTCC2150|Rep:
           2,5-diketo-D-gluconic acid reductase A - Rhodobacterales
           bacterium HTCC2150
          Length = 334

 Score = 93.9 bits (223), Expect = 1e-17
 Identities = 66/180 (36%), Positives = 87/180 (48%), Gaps = 8/180 (4%)
 Frame = +1

Query: 112 MTSVPVT-TLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGE 288
           MT+   T TL+    IP +G GT+     +    +  AI  GYRHI  A  Y NEK VG 
Sbjct: 33  MTNTATTFTLNTTTTIPAVGFGTYLISNDDAKSTISAAIQAGYRHIDTASGYQNEKTVGA 92

Query: 289 AIKTKIQEGVVKREDLFITSKLW--NTF--HRPDLVRGAL---EVSLRNLNIDYLDLYLI 447
            IK  +Q   + R+DLF+T+KLW  N      P      L   + SL  L +DY+DLYLI
Sbjct: 93  GIKAGLQSAGITRKDLFVTAKLWPGNPAWGDAPKTKAQTLDECDASLARLGLDYVDLYLI 152

Query: 448 HWPQAYKEDDAIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRI 627
           H P               G ++      ++ W+AL  L  +G  RS+GVSNFN   L  I
Sbjct: 153 HAPYG-------------GDMR------LEQWRALLELQANGKARSIGVSNFNESHLNEI 193


>UniRef50_Q5UX52 Cluster: Oxidoreductase aldo/keto reductase family;
           n=1; Haloarcula marismortui|Rep: Oxidoreductase
           aldo/keto reductase family - Haloarcula marismortui
           (Halobacterium marismortui)
          Length = 274

 Score = 93.9 bits (223), Expect = 1e-17
 Identities = 61/166 (36%), Positives = 83/166 (50%)
 Frame = +1

Query: 145 GAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQEGVVK 324
           G  +P +G+GTW+       + V+ A+ +GYRHI  A  YGNE++VG      +    V 
Sbjct: 8   GTSVPALGLGTWQLTGQSCRETVETALGMGYRHIDTAQAYGNERQVG----LGMDAAAVD 63

Query: 325 REDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTDADG 504
           RED+F+T+KL  +      VR +   SL  L  DYLDL LIHWP          P  A  
Sbjct: 64  REDVFLTTKLDGSNRDERSVRRSTRESLNKLGTDYLDLLLIHWPNT--------PWMA-- 113

Query: 505 KIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNAS 642
                     +T  A+  +V  GLVR +GVSNF+   L R  D +S
Sbjct: 114 -------SLSETLGAMNDVVEEGLVRHIGVSNFSPSLLDRARDISS 152



 Score = 40.3 bits (90), Expect = 0.14
 Identities = 17/43 (39%), Positives = 27/43 (62%), Gaps = 2/43 (4%)
 Frame = +2

Query: 656 TNQVECHPYLNXKRLKQFCEDRDIMITXYSP--XGXLPTDPGL 778
           T+QV+ HPY + ++L  +C   D+++T YSP   G +  DP L
Sbjct: 157 TDQVQYHPYWDQRKLLDYCRIHDVLLTAYSPLARGGVLDDPAL 199


>UniRef50_Q5B034 Cluster: Putative uncharacterized protein; n=1;
           Emericella nidulans|Rep: Putative uncharacterized
           protein - Emericella nidulans (Aspergillus nidulans)
          Length = 186

 Score = 93.5 bits (222), Expect = 1e-17
 Identities = 61/166 (36%), Positives = 91/166 (54%), Gaps = 1/166 (0%)
 Frame = +1

Query: 136 LSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQEG 315
           L+ GA IP +G+GTWKS+PGEV +A+  A+  GYRHI  A        +G          
Sbjct: 9   LNPGALIPAVGLGTWKSEPGEVARALAHALKTGYRHIDAA--------LG---------- 50

Query: 316 VVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTD 495
            V RE++FITSKLWNT H+P++  G L+ +L  L +D LDL        Y E   + P +
Sbjct: 51  -VPREEIFITSKLWNT-HQPNIKEG-LQKTLDALGVDCLDL--------YNETSDLLPVN 99

Query: 496 ADG-KIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRIL 630
            DG +      D  +TW+ +E     G  +++GV+N++   L+ +L
Sbjct: 100 PDGTRAVDRSWDQSETWRQMEDFYKSGKAKAIGVANWSIPYLEELL 145


>UniRef50_Q4PE96 Cluster: Putative uncharacterized protein; n=1;
           Ustilago maydis|Rep: Putative uncharacterized protein -
           Ustilago maydis (Smut fungus)
          Length = 293

 Score = 93.1 bits (221), Expect = 2e-17
 Identities = 64/170 (37%), Positives = 88/170 (51%), Gaps = 2/170 (1%)
 Frame = +1

Query: 133 TLSNGAKIPVIGIGTWKSKPGEVTQAVKDAID-IGYRHIXCAFVYGNEKEVGEAIKTKIQ 309
           T+ +G  +P  GIG W  +  E  QA+ +A D  GYRH+  A  Y NE + GEA++    
Sbjct: 20  TMVDGYAMPRFGIGAWDMRGSECKQALLNAFDKAGYRHVDTARYYRNEADCGEAVR---- 75

Query: 310 EGVVKREDLFITSKLW-NTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIF 486
           E  V R +LF T+K++ N        R A+E SL    +DYLDL L+H P          
Sbjct: 76  ECSVPRSELFYTTKVYLNEMGGGSKTRLAVEDSLAKAGLDYLDLVLLHAP---------- 125

Query: 487 PTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDN 636
               DG  +F     +D+W  L  LV  G VRSLGVSNF    +Q ++D+
Sbjct: 126 ----DGGKKFR----LDSWDTLTELVQEGKVRSLGVSNFGPHHIQELIDS 167


>UniRef50_Q5FK99 Cluster: Oxidoreductase aldo-keto reductase family;
           n=5; Lactobacillus|Rep: Oxidoreductase aldo-keto
           reductase family - Lactobacillus acidophilus
          Length = 289

 Score = 92.7 bits (220), Expect = 2e-17
 Identities = 64/181 (35%), Positives = 92/181 (50%), Gaps = 1/181 (0%)
 Frame = +1

Query: 112 MTSVPVTTLSNGAKIPVIGIGTWK-SKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGE 288
           MT +P   L++G +IP +G G ++ S   E  +AV+ AI  GYR I  A  Y N+  VGE
Sbjct: 1   MTDIPKIKLNDGNEIPQLGFGVFQISNHDEAVKAVESAISNGYRLIDTAEAYNNQTAVGE 60

Query: 289 AIKTKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYK 468
           AIK       V R+D+F+T+KLW +    +    A++  L+ L  DY+D+ L+H  QAY 
Sbjct: 61  AIKNSD----VNRDDIFLTTKLWVSNFTYEKASKAIDEDLKELGTDYIDMMLLH--QAYG 114

Query: 469 EDDAIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVK 648
                              D    W+ALE     G  +S+GVSNF   QL  +   ++VK
Sbjct: 115 -------------------DVAGAWRALEDAQKAGKTKSIGVSNFWPDQLMNLQLMSNVK 155

Query: 649 P 651
           P
Sbjct: 156 P 156


>UniRef50_Q927P9 Cluster: Lin2739 protein; n=12; Bacteria|Rep:
           Lin2739 protein - Listeria innocua
          Length = 283

 Score = 92.3 bits (219), Expect = 3e-17
 Identities = 62/170 (36%), Positives = 92/170 (54%), Gaps = 1/170 (0%)
 Frame = +1

Query: 136 LSNGAKIPVIGIGTWK-SKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQE 312
           L+NG ++P++G GT++ +  GE  QAVK+AI  GYRHI  A  Y NE+ VG  I      
Sbjct: 6   LNNGIEVPILGFGTYQITDAGEAEQAVKEAIAAGYRHIDTAQSYMNEEAVGRGIAA---- 61

Query: 313 GVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPT 492
             V R++LFIT+K+W        V  + + SL+ L +DY+DL LIH P            
Sbjct: 62  SGVDRKELFITTKIWVENVSYKGVMSSFDRSLKRLGLDYIDLLLIHQP------------ 109

Query: 493 DADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNAS 642
                  ++DV     W A+E L   G ++++GVSNF    + R++D A+
Sbjct: 110 -------YNDV--YGAWMAMEELQAQGKIKAIGVSNFG---VDRVVDLAA 147


>UniRef50_Q14LU6 Cluster: Putative aldo/keto reductase
           oxidoreductase protein; n=1; Spiroplasma citri|Rep:
           Putative aldo/keto reductase oxidoreductase protein -
           Spiroplasma citri
          Length = 138

 Score = 92.3 bits (219), Expect = 3e-17
 Identities = 47/105 (44%), Positives = 70/105 (66%), Gaps = 1/105 (0%)
 Frame = +1

Query: 136 LSNGAKIPVIGIGTWK-SKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQE 312
           L NG +IP+IG+GT+K +   EV QA+  A+  GYRHI  A +YGNE+ +G+AIK    +
Sbjct: 10  LFNGVEIPLIGLGTYKMTDEHEVYQAIITALQNGYRHIDTAQIYGNEELIGKAIK----D 65

Query: 313 GVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLI 447
             V R+++F+TSK+WN  H+ D     ++  L+ L+ DYLDL L+
Sbjct: 66  SGVPRKEIFLTSKIWNANHKYDAALQEIDNILKRLDTDYLDLCLV 110


>UniRef50_Q1Q8W8 Cluster: Aldo/keto reductase; n=1; Psychrobacter
           cryohalolentis K5|Rep: Aldo/keto reductase -
           Psychrobacter cryohalolentis (strain K5)
          Length = 282

 Score = 91.9 bits (218), Expect = 4e-17
 Identities = 60/155 (38%), Positives = 84/155 (54%), Gaps = 2/155 (1%)
 Frame = +1

Query: 148 AKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQEGVVKR 327
           A IPV+G+GTW+S   +    V   + +GY HI  A  YGNE EVG+ IK   Q GV  R
Sbjct: 14  ANIPVLGLGTWQSTGQDCIDVVSQGLRMGYEHIDTAQAYGNEVEVGKGIK---QSGVA-R 69

Query: 328 EDLFITSKLW--NTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTDAD 501
           +  F+T+K++  +    P+ +  A + SL NL+ DY+DL L+HWP              D
Sbjct: 70  DKFFLTTKIFPDDMKFEPEKLVAAAKRSLENLDTDYVDLLLLHWP--------------D 115

Query: 502 GKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFN 606
            ++  S     +T  AL  L   GL R++GVSNFN
Sbjct: 116 DRVPLS-----ETIPALCELQKQGLTRNIGVSNFN 145



 Score = 35.5 bits (78), Expect = 3.9
 Identities = 14/32 (43%), Positives = 20/32 (62%)
 Frame = +2

Query: 653 VTNQVECHPYLNXKRLKQFCEDRDIMITXYSP 748
           V NQVE HP++  K L+ F  +  I++  YSP
Sbjct: 161 VVNQVEFHPFIKQKTLQTFLNNHHILLEAYSP 192


>UniRef50_A5DRJ6 Cluster: Putative uncharacterized protein; n=4;
           Pichia guilliermondii|Rep: Putative uncharacterized
           protein - Pichia guilliermondii (Yeast) (Candida
           guilliermondii)
          Length = 287

 Score = 91.9 bits (218), Expect = 4e-17
 Identities = 59/173 (34%), Positives = 92/173 (53%), Gaps = 2/173 (1%)
 Frame = +1

Query: 136 LSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKI-QE 312
           L NG++IP  G+G +     +    V+ A+D+GYR I  A  Y NE+E GE IK  + ++
Sbjct: 12  LLNGSRIPACGVGVYLLPASQTAGIVEKALDVGYRLIDTAQEYENERETGEGIKAWLGKD 71

Query: 313 GVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNL-NIDYLDLYLIHWPQAYKEDDAIFP 489
              KRED+  T+K+ N     D    +L+ SL  + +++Y+DL LIH P + K+      
Sbjct: 72  KNNKREDVLYTTKITNLNQGYDRTWRSLKESLNKVKHLEYIDLVLIHDPLSDKK------ 125

Query: 490 TDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVK 648
                         ++TWKAL+  V  G+V+S+GVSNF    +Q + D   +K
Sbjct: 126 ------------TRIETWKALQEAVDSGMVKSIGVSNFGKHHIQELYDWEGLK 166


>UniRef50_A6SI80 Cluster: Putative uncharacterized protein; n=1;
           Botryotinia fuckeliana B05.10|Rep: Putative
           uncharacterized protein - Botryotinia fuckeliana B05.10
          Length = 253

 Score = 91.5 bits (217), Expect = 6e-17
 Identities = 62/183 (33%), Positives = 90/183 (49%), Gaps = 7/183 (3%)
 Frame = +1

Query: 124 PVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTK 303
           P   L++G ++P +G G WK         V +AI  GYR                     
Sbjct: 4   PTLKLNSGHEMPQVGFGLWKVDNATCADTVYNAIKTGYR--------------------- 42

Query: 304 IQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYK-EDDA 480
           + +G     DLFI SKLWN+FH  D V       L +  IDY DL+++H+P A +  D A
Sbjct: 43  LFDGAC---DLFIVSKLWNSFHDGDRVGPITRKQLADWGIDYFDLFIVHFPVALRYVDPA 99

Query: 481 I-FP-----TDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNAS 642
           + +P     +D +G +Q S     +TW+A+E LV  GL +S+GVSNF    L  +L  A 
Sbjct: 100 VRYPPGWQYSDKEGDVQQSKASIQETWQAMEKLVDEGLAKSIGVSNFQGALLIDLLRYAR 159

Query: 643 VKP 651
           ++P
Sbjct: 160 IRP 162


>UniRef50_Q09632 Cluster: Probable oxidoreductase ZK1290.5; n=2;
           Caenorhabditis|Rep: Probable oxidoreductase ZK1290.5 -
           Caenorhabditis elegans
          Length = 321

 Score = 91.5 bits (217), Expect = 6e-17
 Identities = 66/178 (37%), Positives = 94/178 (52%), Gaps = 1/178 (0%)
 Frame = +1

Query: 121 VPVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAID-IGYRHIXCAFVYGNEKEVGEAIK 297
           +P T LSN  ++P+IG+GT  S  G    AV  +I   GYR I  A  YG EK++G A+K
Sbjct: 2   IPTTVLSNNVEMPLIGLGTTHSG-GYYHDAVLHSIKKCGYRLIDTAKRYGVEKQLGIAVK 60

Query: 298 TKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDD 477
                  V RE++F+++KLW      D V  A + S   L  DYLD+Y+IH PQ    D 
Sbjct: 61  NCS----VPREEMFLSTKLWPV-DCGDEVYNAFQTSCEKLQTDYLDMYMIHMPQL--PDW 113

Query: 478 AIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKP 651
            +   +   K          TW+ +E L     VRS+GVSN++ + L  +L+ AS+ P
Sbjct: 114 IVNQKETKEK----------TWRQMELLYEDEHVRSIGVSNYSIEDLDELLEFASILP 161


>UniRef50_Q8EVT8 Cluster: Oxidoreductase-aldo/keto reductase family;
           n=1; Mycoplasma penetrans|Rep: Oxidoreductase-aldo/keto
           reductase family - Mycoplasma penetrans
          Length = 299

 Score = 90.6 bits (215), Expect = 1e-16
 Identities = 60/178 (33%), Positives = 96/178 (53%), Gaps = 2/178 (1%)
 Frame = +1

Query: 124 PVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTK 303
           P+ TL++G +IP+IG+GT          A+K A++IG R    A +YGNEKEVGE I+  
Sbjct: 35  PLLTLNDGYQIPIIGLGTTSLHNQTCKNAIKAALEIGIRLFDTASLYGNEKEVGETIR-- 92

Query: 304 IQEGVVKREDLFITSKLW--NTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDD 477
             E  + R ++F+ +KL+    F  P+    A+E +L  LN DY+D+ L+H P    E+D
Sbjct: 93  --ESNINRNEIFVITKLYPGAQFANPE---KAIEEALNKLNTDYIDMMLLHHP---GEND 144

Query: 478 AIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKP 651
                             V  +KA+E  +  G ++S+G+SN+  K++   L   ++KP
Sbjct: 145 ------------------VKAYKAIEKYIEKGKIKSVGLSNWYIKEINSFLPQINIKP 184


>UniRef50_Q9X265 Cluster: Oxidoreductase, aldo/keto reductase
           family; n=2; Thermotoga|Rep: Oxidoreductase, aldo/keto
           reductase family - Thermotoga maritima
          Length = 274

 Score = 90.2 bits (214), Expect = 1e-16
 Identities = 62/177 (35%), Positives = 92/177 (51%), Gaps = 12/177 (6%)
 Frame = +1

Query: 145 GAKIPVIGIGTWK---------SKPGEVTQAVKDAIDIGYRHIXCAFVYGN---EKEVGE 288
           G +IP +G+GTW          S+  E+ + +K AI +GY HI  A  YG    E+ +G+
Sbjct: 10  GEEIPALGLGTWGIGGFETPDYSRDEEMVELLKTAIKMGYTHIDTAEYYGGGHTEELIGK 69

Query: 289 AIKTKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYK 468
           AIK        +REDLFI SK+W T  R D +  +LE +L+ L+ DY+DLYLIHWP    
Sbjct: 70  AIKD------FRREDLFIVSKVWPTHLRRDDLLRSLENTLKRLDTDYVDLYLIHWPN--- 120

Query: 469 EDDAIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNA 639
                            ++   +T  A+   V  GL+R +GVSNF+ + L+  +  +
Sbjct: 121 ----------------PEIPLEETLSAMAEGVRQGLIRYIGVSNFDRRLLEEAISKS 161


>UniRef50_Q9HM42 Cluster: Alcohol dehydrogenase related protein;
           n=1; Thermoplasma acidophilum|Rep: Alcohol dehydrogenase
           related protein - Thermoplasma acidophilum
          Length = 284

 Score = 90.2 bits (214), Expect = 1e-16
 Identities = 58/164 (35%), Positives = 84/164 (51%), Gaps = 2/164 (1%)
 Frame = +1

Query: 145 GAKIPVIGIGTW--KSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQEGV 318
           G K+ VIG+GTW  +    E  ++++ A+D G   I  A +YG E  VGEAIK       
Sbjct: 13  GRKVSVIGVGTWSLEGSRSENVRSIRYALDHGVNFIDTAEMYGTEDIVGEAIKG------ 66

Query: 319 VKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTDA 498
            +REDLFI +K+W T      V  + E SL+ L  DY+DLY +HWP              
Sbjct: 67  YRREDLFIATKVWPTHFAYHDVLKSCEESLKKLGTDYVDLYQLHWPN------------- 113

Query: 499 DGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRIL 630
                   V   +T  A+E LV  G +R +G+SNF+ K+++  +
Sbjct: 114 ------PSVSIKETMSAMEKLVDEGRIRYIGISNFSVKEMKEAM 151


>UniRef50_Q4V008 Cluster: Oxidoreductase; n=4; Proteobacteria|Rep:
           Oxidoreductase - Xanthomonas campestris pv. campestris
           (strain 8004)
          Length = 267

 Score = 89.8 bits (213), Expect = 2e-16
 Identities = 56/150 (37%), Positives = 83/150 (55%)
 Frame = +1

Query: 154 IPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQEGVVKRED 333
           +P  G+GT++ K   V  +V++A+ +GYR I  A +Y NE +VG+AI     +  V R+ 
Sbjct: 3   VPAFGLGTFRLKDQVVIDSVRNALALGYRAIDTAQIYDNEAQVGQAIA----DAGVPRDQ 58

Query: 334 LFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTDADGKIQ 513
           LF+T+K+W      D ++ +L+ SLR L  DY+DL LIHWP          P D     Q
Sbjct: 59  LFVTTKIWVDRFSRDTLQPSLQESLRKLGTDYVDLTLIHWPS---------PKD-----Q 104

Query: 514 FSDVDYVDTWKALEPLVCHGLVRSLGVSNF 603
               +Y++   AL      GL R++GVSNF
Sbjct: 105 VPMREYLE---ALADAKAQGLTRAIGVSNF 131


>UniRef50_Q6WGK4 Cluster: Aldose reductase; n=1; Pristionchus
           pacificus|Rep: Aldose reductase - Pristionchus pacificus
          Length = 293

 Score = 89.4 bits (212), Expect = 2e-16
 Identities = 54/168 (32%), Positives = 89/168 (52%), Gaps = 1/168 (0%)
 Frame = +1

Query: 151 KIPVIGIGTWKSKPGEV-TQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQEGVVKR 327
           ++P+IG+GT++ +   V T  + +A  +GYR I  A +Y NE  +G  +   +++  +KR
Sbjct: 15  RMPMIGVGTYQVQSQSVLTDTIDEAFRLGYRFIDTAQIYRNEAILGRILPDLLEKHSLKR 74

Query: 328 EDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTDADGK 507
           ED+FITSK+            ++  SL +L   Y+DL LIHWP   +       ++    
Sbjct: 75  EDIFITSKVSPINQGKGKTSKSVLKSLTDLQTPYIDLVLIHWPGTSR-----LKSNHKDN 129

Query: 508 IQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKP 651
            +F    YV+    LE L+  G +RS+GVSN+  K L+ +L    + P
Sbjct: 130 AKFRAETYVE----LETLMDEGKIRSIGVSNYEIKHLETLLAECRILP 173



 Score = 34.7 bits (76), Expect = 6.8
 Identities = 12/32 (37%), Positives = 18/32 (56%)
 Frame = +2

Query: 659 NQVECHPYLNXKRLKQFCEDRDIMITXYSPXG 754
           NQ ECHP+     L ++C+++ I    YS  G
Sbjct: 176 NQCECHPHFRNSELAEYCKEKGIHFQAYSSLG 207


>UniRef50_Q4DJ59 Cluster: Aldo/keto reductase, putative; n=2;
           Trypanosoma|Rep: Aldo/keto reductase, putative -
           Trypanosoma cruzi
          Length = 322

 Score = 89.4 bits (212), Expect = 2e-16
 Identities = 58/176 (32%), Positives = 90/176 (51%), Gaps = 1/176 (0%)
 Frame = +1

Query: 118 SVPVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIK 297
           ++P+   S G +IP +G+GT++    E   AV  A+ +G+R +  A  Y NE+ VG A  
Sbjct: 14  ALPLLESSGGMRIPHMGVGTYELYGDESRIAVLAALRLGFRLVDTAAGYHNEEHVGAA-- 71

Query: 298 TKIQEGVVKREDLFITSKLW-NTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKED 474
             I+E  V+RE+LF+  K+        +LV   +  S+R L I Y D  LIHWP      
Sbjct: 72  --IEESGVQREELFVVVKIAPKAMASEELVEKGIRESVRKLRIAYADCVLIHWPGC---- 125

Query: 475 DAIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNAS 642
             + P +A+G            WK ++ L   G++R LGVSNF  +    ++ NA+
Sbjct: 126 GGLKPEEAEGHRAARH----RCWKVMQALKKEGIIRHLGVSNFAPRHFPHLVGNAA 177



 Score = 35.5 bits (78), Expect = 3.9
 Identities = 14/32 (43%), Positives = 19/32 (59%)
 Frame = +2

Query: 653 VTNQVECHPYLNXKRLKQFCEDRDIMITXYSP 748
           V NQ+E HP    +    FC +RDI++  YSP
Sbjct: 192 VINQIELHPLCVQQEACDFCRERDIILQQYSP 223


>UniRef50_Q5V6N9 Cluster: Alcohol dehydrogenase; n=2;
           Halobacteriaceae|Rep: Alcohol dehydrogenase - Haloarcula
           marismortui (Halobacterium marismortui)
          Length = 667

 Score = 89.4 bits (212), Expect = 2e-16
 Identities = 55/185 (29%), Positives = 87/185 (47%), Gaps = 18/185 (9%)
 Frame = +1

Query: 151 KIPVIGIGTWKSKPG---EVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQEGVV 321
           ++P IG G  + + G   +   ++  A+D GYR +  A +YGNE  +G  +      G  
Sbjct: 377 RLPAIGFGCSRYRDGTYIDRADSIAAALDAGYRLLDSAELYGNEHRIGRILAAP---GAP 433

Query: 322 KREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAY------------ 465
            R  +FI  K+W T HR   +  A   SL  L ID  D Y +HWP+A             
Sbjct: 434 DRRRVFILGKVWRTNHRRKHMLTACRSSLDELGIDAFDCYALHWPEALAHRGSLTRLAEK 493

Query: 466 ---KEDDAIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDN 636
              +++   FP +  G I+   V     W+ LE L   G  R+LG+ N +  QL+ +++ 
Sbjct: 494 SVARQEALTFPKNDRGDIETDSVSLQRAWENLEALHERGWTRTLGLCNVSQTQLETVIET 553

Query: 637 ASVKP 651
            +V+P
Sbjct: 554 GTVRP 558


>UniRef50_A5ZYE6 Cluster: Putative uncharacterized protein; n=1;
           Ruminococcus obeum ATCC 29174|Rep: Putative
           uncharacterized protein - Ruminococcus obeum ATCC 29174
          Length = 263

 Score = 89.0 bits (211), Expect = 3e-16
 Identities = 58/167 (34%), Positives = 87/167 (52%), Gaps = 1/167 (0%)
 Frame = +1

Query: 154 IPVIGIGTWKSKPG-EVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQEGVVKRE 330
           +P++G+G +K+    E   A+  A+  GYR +  A  Y NE+ VG      I +  V R+
Sbjct: 1   MPLLGLGLYKTTDAVEAEDAIAAAVQNGYRLLDTASAYKNEEFVG----CGIAKCGVPRK 56

Query: 331 DLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTDADGKI 510
           DLFIT+K+WN   R   V GA + SL  L +DY+DLYLIHWP               G  
Sbjct: 57  DLFITTKIWNNAQRLGDVEGAFQRSLDRLGLDYIDLYLIHWP-------------VPG-- 101

Query: 511 QFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKP 651
                 +++TWK +E ++  G   S+GVSNF  + L+ +   + + P
Sbjct: 102 -----CFLNTWKDMEKILESGRALSIGVSNFEIRHLEELRRVSGIVP 143



 Score = 37.9 bits (84), Expect = 0.73
 Identities = 13/30 (43%), Positives = 19/30 (63%)
 Frame = +2

Query: 659 NQVECHPYLNXKRLKQFCEDRDIMITXYSP 748
           NQ+ECHP    K L ++C+  DI +  Y+P
Sbjct: 146 NQIECHPLCYPKELIEYCQANDIQVQAYAP 175


>UniRef50_Q03U37 Cluster: Aldo/keto reductase of diketogulonate
           reductase family; n=5; Lactobacillus|Rep: Aldo/keto
           reductase of diketogulonate reductase family -
           Lactobacillus brevis (strain ATCC 367 / JCM 1170)
          Length = 282

 Score = 88.6 bits (210), Expect = 4e-16
 Identities = 66/184 (35%), Positives = 93/184 (50%), Gaps = 4/184 (2%)
 Frame = +1

Query: 112 MTSVPVTT---LSNGAKIPVIGIGTWK-SKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKE 279
           MT   +T    L++G ++PV+G GT+  +    +  A++ A D GYR    A +Y NE  
Sbjct: 1   MTPTEITATRKLADGRQMPVMGFGTYLLNDQPTMNTAIQTAWDAGYRMFDTAMLYRNEDI 60

Query: 280 VGEAIKTKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQ 459
           +G AI+   Q G+  RE LF+TSK+       D    A+E SL+ L  DYLDL LIHWP 
Sbjct: 61  LGPAIQ---QLGL-PREGLFLTSKVAEIVQGYDQTMKAVEGSLKRLQTDYLDLLLIHWP- 115

Query: 460 AYKEDDAIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNA 639
             +E                   + DTW+ALE L   G V+S+GVSN+    L+ +   A
Sbjct: 116 -VRE------------------HFFDTWRALEQLKADGQVKSIGVSNYTIAHLELLATKA 156

Query: 640 SVKP 651
              P
Sbjct: 157 KEMP 160



 Score = 38.7 bits (86), Expect = 0.42
 Identities = 16/34 (47%), Positives = 22/34 (64%)
 Frame = +2

Query: 653 VTNQVECHPYLNXKRLKQFCEDRDIMITXYSPXG 754
           V NQVE HPYLN + L  + ++ DI+   +SP G
Sbjct: 161 VVNQVEYHPYLNQQALADYDQEHDIVTEAWSPLG 194


>UniRef50_A7BES9 Cluster: Putative uncharacterized protein; n=1;
           Actinomyces odontolyticus ATCC 17982|Rep: Putative
           uncharacterized protein - Actinomyces odontolyticus ATCC
           17982
          Length = 282

 Score = 88.6 bits (210), Expect = 4e-16
 Identities = 71/241 (29%), Positives = 111/241 (46%)
 Frame = +1

Query: 133 TLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQE 312
           TL+NG  IP +G+GT+  +P +   AV  A+D  Y  I  A VY NE+ VG  ++   + 
Sbjct: 5   TLNNGITIPQVGLGTYLLEPDDAQSAVTYALDNDYTLIDTANVYVNERAVGRGMRASSK- 63

Query: 313 GVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPT 492
               R+++F+ +KLW +F        A+E +L  L  DY+DL ++H P            
Sbjct: 64  ---ARDEIFLETKLWPSFFER---ASAVEETLERLGTDYIDLMILHQPAG---------- 107

Query: 493 DADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPGH*PGRM 672
                      D V  ++ LE     G +R++G+SNF+  Q QRILD   V P       
Sbjct: 108 -----------DTVAGYRILEKAHKEGKIRAIGLSNFDVAQTQRILDECEVVPTINQVEC 156

Query: 673 PSVFKPXAIEAVLRRP*YYDNGVLPRWGXPDRPWAKPGDPHLMEDPKLKEIADRLGKXAA 852
              F    ++A+L+      N  L  W     P    G+  +M +P ++ +A+   K  A
Sbjct: 157 HPYFPQTELKALLKD----HNITLQAW----YPLGGRGNDSIMSEPIVQGLAEEHSKSPA 208

Query: 853 Q 855
           Q
Sbjct: 209 Q 209


>UniRef50_A3VRL4 Cluster: Putative uncharacterized protein; n=1;
           Parvularcula bermudensis HTCC2503|Rep: Putative
           uncharacterized protein - Parvularcula bermudensis
           HTCC2503
          Length = 278

 Score = 88.2 bits (209), Expect = 5e-16
 Identities = 41/101 (40%), Positives = 64/101 (63%)
 Frame = +1

Query: 154 IPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQEGVVKRED 333
           IP +G GTW+ +  +   + + AI+ GYRHI  A +Y NEK+VGE IK    +  + R++
Sbjct: 11  IPRLGFGTWQLEGEDARTSTRTAIETGYRHIDGAAIYKNEKKVGEGIK----DSGIPRDE 66

Query: 334 LFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWP 456
           LF+T+K+WN   +      A++ SL  L +DY++L L+HWP
Sbjct: 67  LFVTTKIWNEDIQKGRHSEAVDESLDRLGLDYVNLILLHWP 107


>UniRef50_Q5KD52 Cluster: Oxidoreductase, putative; n=1;
           Filobasidiella neoformans|Rep: Oxidoreductase, putative
           - Cryptococcus neoformans (Filobasidiella neoformans)
          Length = 321

 Score = 88.2 bits (209), Expect = 5e-16
 Identities = 66/177 (37%), Positives = 92/177 (51%), Gaps = 4/177 (2%)
 Frame = +1

Query: 133 TLSNGAKIPVIGIGTWKSKPGEVTQ-AVKDAIDIGYRHIXCA---FVYGNEKEVGEAIKT 300
           TL++G +IP I  GTWK  P EVT   V  AID+G+ HI  A    VY NE+EVG+AIK 
Sbjct: 7   TLNDGHRIPAIAFGTWKI-PKEVTPFQVGQAIDVGFDHIDTAQGRIVYHNEEEVGQAIK- 64

Query: 301 KIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDA 480
              E  + R  L++T+K W+        R ++  SL  L ++YLDLYLIH PQ  K D  
Sbjct: 65  ---ESGLSRNQLWVTTK-WSGIDGKG-ARQSIGESLEKLGLEYLDLYLIHSPQVTKGDIK 119

Query: 481 IFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKP 651
               + +   +      +   K +          S    +FN +QLQ +L +A+VKP
Sbjct: 120 GAWKELETLQKEGKTKSIGVSKQVYYQTIFFASLSDVWDSFNKEQLQELLAHATVKP 176


>UniRef50_UPI00005A2CCB Cluster: PREDICTED: similar to Aldose
           reductase (AR) (Aldehyde reductase); n=1; Canis lupus
           familiaris|Rep: PREDICTED: similar to Aldose reductase
           (AR) (Aldehyde reductase) - Canis familiaris
          Length = 182

 Score = 87.4 bits (207), Expect = 9e-16
 Identities = 39/78 (50%), Positives = 55/78 (70%)
 Frame = +1

Query: 136 LSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQEG 315
           L NG K+P++G+ TWKS P +VT+AVK  +D+GY HI C     N++EVG A++ K++  
Sbjct: 25  LGNGIKVPIMGLATWKSPPSKVTEAVKVVMDLGYCHIDCTHKLQNKREVGLAVQEKLKGQ 84

Query: 316 VVKREDLFITSKLWNTFH 369
            VKREDL I S+L +T H
Sbjct: 85  GVKREDLSILSELQHTHH 102


>UniRef50_P15339 Cluster: 2,5-diketo-D-gluconic acid reductase B;
           n=6; Actinomycetales|Rep: 2,5-diketo-D-gluconic acid
           reductase B - Corynebacterium sp. (strain SHS752001)
          Length = 277

 Score = 87.0 bits (206), Expect = 1e-15
 Identities = 58/180 (32%), Positives = 88/180 (48%)
 Frame = +1

Query: 112 MTSVPVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEA 291
           M ++P  +L++G      G+GT+  +  E   A+  AID GYR +  A  Y NE EVG A
Sbjct: 1   MPNIPTISLNDGRPFAEPGLGTYNLRGDEGVAAMVAAIDSGYRLLDTAVNYENESEVGRA 60

Query: 292 IKTKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKE 471
           ++       V R++L + SK+    H       ++  SL  L +D +DL LIHW      
Sbjct: 61  VRA----SSVDRDELIVASKIPGRQHGRAEAVDSIRGSLDRLGLDVIDLQLIHW------ 110

Query: 472 DDAIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKP 651
                P  + G+       ++DTW+ +      GLVRS+GVSNF    L+ ++D   V P
Sbjct: 111 -----PNPSVGR-------WLDTWRGMIDAREAGLVRSIGVSNFTEPMLKTLIDETGVTP 158


>UniRef50_Q6U5V3 Cluster: Putative uncharacterized protein; n=1;
           Klebsiella pneumoniae|Rep: Putative uncharacterized
           protein - Klebsiella pneumoniae
          Length = 279

 Score = 86.6 bits (205), Expect = 2e-15
 Identities = 56/172 (32%), Positives = 84/172 (48%)
 Frame = +1

Query: 136 LSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQEG 315
           L++G  +P  G G W     +V   ++ A+  G+RH   A  Y NE  VG A++      
Sbjct: 8   LNDGYYMPRPGCGLWLIDNRDVDSLIRQALKAGFRHFDTAQAYFNEDGVGRALRYT---- 63

Query: 316 VVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTD 495
            V RE LFITSK+            +   +L  L ++YL+L+LIHWP   K         
Sbjct: 64  EVPREQLFITSKIRGRDMGYARTLVSFNETLERLGVEYLELFLIHWPIPAKN-------- 115

Query: 496 ADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKP 651
                      YV+TW+A   L   GL+RS+GVSNF  + ++R++++  V P
Sbjct: 116 ----------LYVETWEASIELEASGLIRSIGVSNFTCQHIERLIEDTGVVP 157


>UniRef50_A2RMU6 Cluster: Oxidoreductase, aldo/keto reductase
           family; n=3; Lactococcus lactis|Rep: Oxidoreductase,
           aldo/keto reductase family - Lactococcus lactis subsp.
           cremoris (strain MG1363)
          Length = 281

 Score = 86.6 bits (205), Expect = 2e-15
 Identities = 76/243 (31%), Positives = 116/243 (47%), Gaps = 3/243 (1%)
 Frame = +1

Query: 136 LSNGAKIPVIGIGTWKSKPGEVTQ-AVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQE 312
           L++G  IP  G+G ++   GE T+ AVK+A+ +GYRHI  A  Y NE+ VG AI +    
Sbjct: 7   LNDGNIIPQFGLGVYQIPEGEATENAVKEALRLGYRHIDTAHAYQNERSVGRAIHS---S 63

Query: 313 GVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPT 492
           G+   E ++ITSKLW + +  D    A+E  L  LN+  +DL L+H              
Sbjct: 64  GIPISE-IWITSKLWPSDY--DDASQAIERMLELLNLKQIDLLLLHQQVG---------- 110

Query: 493 DADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPGH*PGRM 672
                      +Y   W ALE  V  G V+S+G+SNF+ ++L  + + A +K    P  +
Sbjct: 111 -----------NYRKAWIALENAVKSGKVKSIGISNFDGERLVDLFNFADIK----PSAL 155

Query: 673 PSVFKPXAIEAVLRRP*YYDNGVLPRWGXPDRPW--AKPGDPHLMEDPKLKEIADRLGKX 846
                P   +  L+         L  +G     W     GD  L+++ +LK+IA +  K 
Sbjct: 156 QVETHPYHQQKELQE-------FLKPYGTKIESWYPLGHGDQRLLDESRLKKIAQKYNKT 208

Query: 847 AAQ 855
            AQ
Sbjct: 209 VAQ 211


>UniRef50_A0L1A2 Cluster: Aldo/keto reductase; n=8;
           Gammaproteobacteria|Rep: Aldo/keto reductase -
           Shewanella sp. (strain ANA-3)
          Length = 280

 Score = 86.6 bits (205), Expect = 2e-15
 Identities = 65/176 (36%), Positives = 90/176 (51%), Gaps = 3/176 (1%)
 Frame = +1

Query: 112 MTSVPVTTLSNGAKI---PVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEV 282
           MT    TT SN A +   P++G GT++ K      AV  A++ G RHI  A +YGNE+ V
Sbjct: 1   MTQTNATT-SNQAPLTAMPMLGTGTFRLKDNAAFDAVLMALEEGSRHIDTAQIYGNEQAV 59

Query: 283 GEAIKTKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQA 462
           G+AI T      + RE+LFIT+K+W      +    ++  SL  L   YLDL LIHWP  
Sbjct: 60  GDAINTS----GIPREELFITTKVWTENLTKERFETSVIDSLTALQTKYLDLLLIHWPLN 115

Query: 463 YKEDDAIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRIL 630
             E               S V+Y+   KA+   +  GL R +GVSNF + QL + +
Sbjct: 116 SDEP--------------SMVEYLSELKAV---LDKGLTRRIGVSNFTNAQLAQAI 154



 Score = 40.7 bits (91), Expect = 0.10
 Identities = 14/31 (45%), Positives = 21/31 (67%)
 Frame = +2

Query: 656 TNQVECHPYLNXKRLKQFCEDRDIMITXYSP 748
           TNQVE HPYL  +++  FC   ++++T Y P
Sbjct: 164 TNQVEVHPYLINRKVTDFCRQHNVLVTGYMP 194


>UniRef50_Q4WUF7 Cluster: Aldo-keto reductase, putative; n=3;
           Pezizomycotina|Rep: Aldo-keto reductase, putative -
           Aspergillus fumigatus (Sartorya fumigata)
          Length = 283

 Score = 86.6 bits (205), Expect = 2e-15
 Identities = 58/175 (33%), Positives = 91/175 (52%), Gaps = 2/175 (1%)
 Frame = +1

Query: 139 SNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQEGV 318
           ++  KIP +G G ++S  G+  Q+   A++ GYRHI  A  YGNEKEVGEA++    +  
Sbjct: 15  NSDVKIPRLGFGVYRSPTGQCVQSSLRALEAGYRHIDTAQFYGNEKEVGEALR----KCG 70

Query: 319 VKREDLFITSKLWNTFHRPDLVRGALEVSLRNL--NIDYLDLYLIHWPQAYKEDDAIFPT 492
           + R D+F+T+K+ +    P+     L  S+  +     Y+DL+LIH             +
Sbjct: 71  IPRSDVFVTTKILSPAGSPEATYQKLLESVEKIGGRDGYVDLFLIH-------------S 117

Query: 493 DADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPGH 657
            + G     ++     W+ALE L+  G  RS+GVSNF  K ++ +   A V P H
Sbjct: 118 SSSGSAGRKEL-----WQALERLLEEGKTRSIGVSNFGVKHIEEMKAYAKVWPPH 167


>UniRef50_Q11DV1 Cluster: Aldo/keto reductase; n=10;
           Alphaproteobacteria|Rep: Aldo/keto reductase -
           Mesorhizobium sp. (strain BNC1)
          Length = 274

 Score = 85.0 bits (201), Expect = 5e-15
 Identities = 38/109 (34%), Positives = 63/109 (57%)
 Frame = +1

Query: 130 TTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQ 309
           T  ++GA IP +G G ++    EV + +  A++ G+RH   A +Y NE  +G A+    +
Sbjct: 3   TVTAHGATIPALGFGVFRMSDAEVERIIPAALEAGFRHFDTAQIYQNEAALGRAL----E 58

Query: 310 EGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWP 456
               +REDLF+T+K+W   +  D    +++ SL  L +D +DL L+HWP
Sbjct: 59  RAGARREDLFLTTKVWVDNYSADKFAASVDESLEKLKVDQVDLLLLHWP 107



 Score = 35.5 bits (78), Expect = 3.9
 Identities = 19/47 (40%), Positives = 23/47 (48%), Gaps = 2/47 (4%)
 Frame = +2

Query: 653 VTNQVECHPYLNXKRLKQFCEDRDIMITXY--SPXGXLPTDPGLSLV 787
           VTNQVE HPYL    L     D  + +T Y     G +P DP L  +
Sbjct: 154 VTNQVELHPYLPQHSLVAAARDSAVAVTAYYGMADGAVPKDPVLQQI 200


>UniRef50_O14088 Cluster: Xylose and arabinose reductase; n=1;
           Schizosaccharomyces pombe|Rep: Xylose and arabinose
           reductase - Schizosaccharomyces pombe (Fission yeast)
          Length = 275

 Score = 85.0 bits (201), Expect = 5e-15
 Identities = 54/167 (32%), Positives = 84/167 (50%)
 Frame = +1

Query: 136 LSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQEG 315
           L+NG K P    G++     +   +V  A+  GYRHI  A +Y NE + G AI   ++E 
Sbjct: 8   LNNGLKCPQFAYGSYMVNRTKCFDSVYAALQCGYRHIDSAQMYHNEADCGRAILKFMEET 67

Query: 316 VVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTD 495
             KRED++ TSKL N          +++ S++   + Y+DL+L+H P             
Sbjct: 68  GTKREDIWFTSKL-NDLSGYKSTLSSIDASVKACGLGYIDLFLLHSPYG----------- 115

Query: 496 ADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDN 636
                     D +++WKALE  V  G +R++GVSNF    +Q +LD+
Sbjct: 116 ----------DRIESWKALEKGVEEGKLRAIGVSNFGPHHIQELLDS 152



 Score = 34.3 bits (75), Expect = 9.0
 Identities = 10/30 (33%), Positives = 20/30 (66%)
 Frame = +2

Query: 659 NQVECHPYLNXKRLKQFCEDRDIMITXYSP 748
           NQ+E HP+ + +++  +CE + I +  Y+P
Sbjct: 161 NQIELHPFCSQQKVVDYCESKGIQLAAYAP 190


>UniRef50_A7D6Q0 Cluster: Aldo/keto reductase; n=1; Halorubrum
           lacusprofundi ATCC 49239|Rep: Aldo/keto reductase -
           Halorubrum lacusprofundi ATCC 49239
          Length = 309

 Score = 85.0 bits (201), Expect = 5e-15
 Identities = 57/168 (33%), Positives = 87/168 (51%), Gaps = 1/168 (0%)
 Frame = +1

Query: 118 SVPVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIK 297
           ++P  TL +G  +P +G+GT+     ++  +V+ A+  GY HI  A  Y NE+ +GE + 
Sbjct: 33  TIPTQTLPSGDTLPALGLGTYALDDDQIADSVRAALSSGYTHIDTAEGYHNEEAIGEVL- 91

Query: 298 TKIQEGVVKREDLFITSK-LWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKED 474
                    R+D+F+TSK L        L++ + E SL  L  DYLDLYLIHWP      
Sbjct: 92  -----AEYDRDDVFLTSKVLAKNLGYESLIQ-SCEASLERLETDYLDLYLIHWPN----- 140

Query: 475 DAIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQL 618
               P           +   ++ +A+  L   GLVR++GVSNF++ QL
Sbjct: 141 ----PA----------ISLRESLQAMAELHDRGLVRNVGVSNFSAYQL 174


>UniRef50_P91021 Cluster: Putative uncharacterized protein; n=1;
           Caenorhabditis elegans|Rep: Putative uncharacterized
           protein - Caenorhabditis elegans
          Length = 134

 Score = 84.6 bits (200), Expect = 6e-15
 Identities = 44/84 (52%), Positives = 54/84 (64%)
 Frame = +1

Query: 133 TLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQE 312
           TLSN   +P +G+GTW+S   +V  AVK A+  GY  I  A  Y NE+ +G AIK  I E
Sbjct: 49  TLSNAHSMPAVGLGTWQSNAEDVISAVKAAVKNGYSLIDTASGYNNEEFIGTAIKEVIAE 108

Query: 313 GVVKREDLFITSKLWNTFHRPDLV 384
           GVVKREDLFIT+K+ N F    LV
Sbjct: 109 GVVKREDLFITTKVPNLFSSLRLV 132


>UniRef50_Q4P1G1 Cluster: Putative uncharacterized protein; n=1;
           Ustilago maydis|Rep: Putative uncharacterized protein -
           Ustilago maydis (Smut fungus)
          Length = 320

 Score = 84.6 bits (200), Expect = 6e-15
 Identities = 55/172 (31%), Positives = 91/172 (52%), Gaps = 1/172 (0%)
 Frame = +1

Query: 121 VPVTTLSNGAKIPVIGIGTWKSK-PGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIK 297
           +P   L++G ++P +  GT  +    +  + V  A+D G+R I  A VY NE  +G  I+
Sbjct: 3   IPTVRLASGLELPRLAFGTGTALYNSDAAKQVTMALDSGFRFIDGAEVYANEASMGAGIE 62

Query: 298 TKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDD 477
           + +    +KR D+++ +K+     + DL + A++V L+ L +D LD YL+H P       
Sbjct: 63  SFLASSGLKRNDIYVLTKVGKEGMK-DL-QSAIKVELQKLKVDQLDSYLLHLP------- 113

Query: 478 AIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILD 633
              P   DG         VD WK LE +   GL +S+GVSN+ +  +Q++LD
Sbjct: 114 ---PRGQDGL-----PSNVDAWKELEKIKQAGLTKSIGVSNWLASDIQQLLD 157


>UniRef50_Q8ZH36 Cluster: 2,5-diketo-D-gluconic acid reductase B;
           n=91; Proteobacteria|Rep: 2,5-diketo-D-gluconic acid
           reductase B - Yersinia pestis
          Length = 267

 Score = 84.6 bits (200), Expect = 6e-15
 Identities = 44/106 (41%), Positives = 63/106 (59%)
 Frame = +1

Query: 154 IPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQEGVVKRED 333
           IPV G+GT++ +   V  +V  A+ +GYR I  A +Y NE  VG+AI    QE  + R++
Sbjct: 3   IPVFGLGTFRLQDQIVIDSVSQALTLGYRAIDTAQIYENEAPVGQAI----QESGINRDE 58

Query: 334 LFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKE 471
           LFIT+K+W      D +  +L  S++ L  DY+DL LIHWP    E
Sbjct: 59  LFITTKIWIANLSKDKLIPSLRESIQKLKTDYVDLTLIHWPSPNDE 104


>UniRef50_UPI000155CAC7 Cluster: PREDICTED: hypothetical protein;
           n=1; Ornithorhynchus anatinus|Rep: PREDICTED:
           hypothetical protein - Ornithorhynchus anatinus
          Length = 419

 Score = 84.2 bits (199), Expect = 9e-15
 Identities = 61/159 (38%), Positives = 85/159 (53%), Gaps = 3/159 (1%)
 Frame = +1

Query: 121 VPVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAI-DIGYRHIXCAFVYGNEKEVGEAIK 297
           VP   L+NG  IP++G+GT     G    AV  A+ + G RHI  A  YG E  +G+AI 
Sbjct: 12  VPTVPLANGLNIPILGLGT-SHVGGYSHDAVIYALKECGIRHIDTAKRYGCELLLGKAI- 69

Query: 298 TKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDD 477
              QE  VKRE+L+IT+KLW T +  +  + +   S   L ++YLDL+LIHWP      D
Sbjct: 70  ---QESGVKREELWITTKLWLTDYGYESAKQSCLESCNRLGVEYLDLFLIHWP------D 120

Query: 478 AIFPTDADGKIQFSDVDYVDTWKALEPLV--CHGLVRSL 588
           A  P  +  + +       +TW+A+E L    H L  SL
Sbjct: 121 AQLPGKSSREAR------AETWRAMEELYDQVHNLQSSL 153


>UniRef50_Q7M4N1 Cluster: Dihydrodiol dehydrogenase DD2; n=2; Homo
           sapiens|Rep: Dihydrodiol dehydrogenase DD2 - Homo
           sapiens (Human)
          Length = 188

 Score = 69.7 bits (163), Expect(2) = 1e-14
 Identities = 34/61 (55%), Positives = 43/61 (70%)
 Frame = +1

Query: 220 AIDIGYRHIXCAFVYGNEKEVGEAIKTKIQEGVVKREDLFITSKLWNTFHRPDLVRGALE 399
           AI+ G+ HI  A VY NE++VG      I +G VKRED+F TSKLW+  HRP+LVR ALE
Sbjct: 2   AIEAGFHHIDSAHVYNNEEQVG------IADGSVKREDIFYTSKLWSNSHRPELVRPALE 55

Query: 400 V 402
           +
Sbjct: 56  I 56



 Score = 43.6 bits (98), Expect = 0.015
 Identities = 19/40 (47%), Positives = 25/40 (62%)
 Frame = +2

Query: 653 VTNQVECHPYLNXKRLKQFCEDRDIMITXYSPXGXLPTDP 772
           V NQVECHPY N ++L  FC  +DI++  YS  G    +P
Sbjct: 98  VCNQVECHPYFNQRKLLDFC--KDIVLVAYSALGSHREEP 135



 Score = 34.3 bits (75), Expect(2) = 1e-14
 Identities = 19/48 (39%), Positives = 28/48 (58%)
 Frame = +1

Query: 505 KIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVK 648
           +I F  VD   TW+A+E        +S+GVSNFN + L+ IL+   +K
Sbjct: 55  EILFDTVDLCATWEAME--------KSIGVSNFNHRLLEMILNKPGLK 94


>UniRef50_Q8EVS8 Cluster: Oxidoreductase; n=1; Mycoplasma
           penetrans|Rep: Oxidoreductase - Mycoplasma penetrans
          Length = 289

 Score = 83.4 bits (197), Expect = 1e-14
 Identities = 50/115 (43%), Positives = 67/115 (58%), Gaps = 1/115 (0%)
 Frame = +1

Query: 115 TSVPVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAI 294
           ++V + TL+NG KIP IG G ++    E    VK AI IGYR I  A  Y NEKE G  I
Sbjct: 4   SNVKLITLNNGNKIPSIGFGVFQIPKEETADCVKKAISIGYRLIDTAQAYHNEKETGLGI 63

Query: 295 KTKIQEGVVKREDLFITSKLW-NTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWP 456
           K       VKRE++F+T+K+W + + R       +E SL+ L+  YLDL L+H P
Sbjct: 64  KL----SGVKREEIFLTTKVWVSNYER--CYESVIE-SLKRLDTSYLDLILLHQP 111


  Database: uniref50
    Posted date:  Oct 5, 2007 11:19 AM
  Number of letters in database: 575,637,011
  Number of sequences in database:  1,657,284
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 1,023,252,796
Number of Sequences: 1657284
Number of extensions: 18490190
Number of successful extensions: 52015
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 48502
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 51438
length of database: 575,637,011
effective HSP length: 104
effective length of database: 403,279,475
effective search space used: 171393776875
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

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