Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= 030731E7_G07_e631_13.seq
(1589 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
X15414-1|CAA33460.1| 316|Homo sapiens protein ( Human mRNA for ... 250 1e-65
M59783-1|AAA51712.1| 316|Homo sapiens aldose reductase protein. 250 1e-65
M34720-1|AAA35560.1| 316|Homo sapiens protein ( Human aldose re... 250 1e-65
J05474-1|AAA51715.1| 316|Homo sapiens aldose reductase protein. 250 1e-65
J05017-1|AAA51714.1| 316|Homo sapiens ALDR1 protein. 250 1e-65
J04795-1|AAA51713.1| 316|Homo sapiens ALDR1 protein. 250 1e-65
BT019859-1|AAV38662.1| 316|Homo sapiens aldo-keto reductase fam... 250 1e-65
BC010391-1|AAH10391.1| 316|Homo sapiens aldo-keto reductase fam... 250 1e-65
BC000260-1|AAH00260.1| 316|Homo sapiens aldo-keto reductase fam... 250 1e-65
AF328729-1|AAN09721.1| 316|Homo sapiens CTCL tumor antigen HD-C... 250 1e-65
AF032455-1|AAB88851.1| 316|Homo sapiens aldose reductase protein. 250 1e-65
AB209796-1|BAD93033.1| 260|Homo sapiens aldo-keto reductase fam... 250 1e-65
CR542203-1|CAG47000.1| 316|Homo sapiens AKR1B1 protein. 249 2e-65
CR450351-1|CAG29347.1| 316|Homo sapiens AKR1B1 protein. 248 4e-65
BC005387-1|AAH05387.1| 316|Homo sapiens aldo-keto reductase fam... 244 7e-64
U37100-1|AAC17469.1| 316|Homo sapiens aldose reductase-like pep... 240 9e-63
CR541801-1|CAG46600.1| 316|Homo sapiens AKR1B10 protein. 240 9e-63
BT006794-1|AAP35440.1| 316|Homo sapiens aldo-keto reductase fam... 240 9e-63
BC008837-1|AAH08837.1| 316|Homo sapiens aldo-keto reductase fam... 240 9e-63
AF052577-1|AAC36465.1| 316|Homo sapiens aldo-keto reductase pro... 240 9e-63
AF524864-1|AAO13380.1| 316|Homo sapiens aldo-ketoreductase prot... 237 6e-62
J04794-1|AAA51711.1| 325|Homo sapiens ALDR1 protein. 227 9e-59
CR457010-1|CAG33291.1| 325|Homo sapiens AKR1A1 protein. 227 9e-59
BT007003-1|AAP35649.1| 325|Homo sapiens aldo-keto reductase fam... 227 9e-59
BC005394-1|AAH05394.1| 325|Homo sapiens aldo-keto reductase fam... 227 9e-59
BC000670-1|AAH00670.1| 325|Homo sapiens aldo-keto reductase fam... 227 9e-59
AL355480-3|CAI22459.1| 325|Homo sapiens aldo-keto reductase fam... 227 9e-59
AF112485-1|AAF01260.1| 325|Homo sapiens aldehyde reductase prot... 227 9e-59
AF036683-1|AAB92369.1| 325|Homo sapiens aldehyde reductase prot... 227 9e-59
Z28339-1|CAA82193.1| 326|Homo sapiens delta 4-3-oxosteroid 5 be... 182 2e-45
BC130627-1|AAI30628.1| 326|Homo sapiens aldo-keto reductase fam... 182 2e-45
BC130625-1|AAI30626.1| 326|Homo sapiens aldo-keto reductase fam... 182 2e-45
AF283659-1|AAG39381.1| 326|Homo sapiens 5-beta steroid reductas... 182 2e-45
L32592-1|AAB38486.1| 323|Homo sapiens dihydrodiol dehydrogenase... 180 1e-44
U05861-1|AAA18115.1| 323|Homo sapiens hepatic dihydrodiol dehyd... 180 2e-44
U05684-1|AAA16227.1| 323|Homo sapiens dihydrodiol dehydrogenase... 180 2e-44
U05598-1|AAA20937.1| 323|Homo sapiens dihydrodiol dehydrogenase... 180 2e-44
S68330-1|AAD14013.1| 323|Homo sapiens chlordecone reductase hom... 180 2e-44
M86609-1|AAB02880.1| 323|Homo sapiens dihydrodiol dehydrogenase... 180 2e-44
BT007197-1|AAP35861.1| 323|Homo sapiens aldo-keto reductase fam... 180 2e-44
BT006653-1|AAP35299.1| 323|Homo sapiens aldo-keto reductase fam... 180 2e-44
BC063574-1|AAH63574.1| 323|Homo sapiens aldo-keto reductase fam... 180 2e-44
BC040210-1|AAH40210.1| 323|Homo sapiens aldo-keto reductase fam... 180 2e-44
BC020216-1|AAH20216.1| 323|Homo sapiens aldo-keto reductase fam... 180 2e-44
BC015490-1|AAH15490.1| 323|Homo sapiens aldo-keto reductase fam... 180 2e-44
BC007024-1|AAH07024.1| 323|Homo sapiens aldo-keto reductase fam... 180 2e-44
BC002862-1|AAH02862.1| 307|Homo sapiens AKR1CL2 protein protein. 180 2e-44
AL713867-2|CAI16409.1| 323|Homo sapiens aldo-keto reductase fam... 180 2e-44
AL713867-1|CAI16408.1| 323|Homo sapiens aldo-keto reductase fam... 180 2e-44
AL391427-1|CAI14726.1| 323|Homo sapiens aldo-keto reductase fam... 180 2e-44
AF263242-1|AAK58523.1| 320|Homo sapiens aldo-keto reductase loo... 180 2e-44
AB209017-1|BAD92254.1| 286|Homo sapiens aldo-keto reductase fam... 180 2e-44
AB055603-1|BAC54568.1| 307|Homo sapiens aldo-keto reductase rel... 180 2e-44
AB040821-1|BAC54566.1| 263|Homo sapiens aldo-keto reductase rel... 180 2e-44
AB040820-1|BAC54565.1| 250|Homo sapiens aldo-keto reductase rel... 180 2e-44
AB032153-1|BAA92891.1| 323|Homo sapiens bile acid-binding prote... 180 2e-44
AB032150-1|BAA92886.1| 323|Homo sapiens 20 alph-hydroxysteroid ... 180 2e-44
AB031084-1|BAA92884.1| 323|Homo sapiens bile acid-binding prote... 180 2e-44
AB031083-1|BAA92883.1| 323|Homo sapiens 20 alpha-hydroxysteroid... 180 2e-44
AB021654-1|BAA36169.1| 323|Homo sapiens DD2/bile acid-binding p... 180 2e-44
D17793-1|BAA04619.2| 325|Homo sapiens KIAA0119 protein. 179 3e-44
BT007286-1|AAP35950.1| 323|Homo sapiens aldo-keto reductase fam... 179 3e-44
BC019230-1|AAH19230.1| 323|Homo sapiens aldo-keto reductase fam... 179 3e-44
BC001479-1|AAH01479.1| 323|Homo sapiens aldo-keto reductase fam... 179 3e-44
AL391427-4|CAI14729.1| 323|Homo sapiens aldo-keto reductase fam... 179 3e-44
AB032157-1|BAA92892.1| 323|Homo sapiens prostaglandin F synthas... 179 3e-44
AB018580-1|BAA88488.1| 323|Homo sapiens hluPGFS protein. 179 3e-44
S68288-1|AAD14011.1| 323|Homo sapiens chlordecone reductase hom... 176 2e-43
L43839-1|AAB41916.1| 323|Homo sapiens 3-alpha-hydroxysteroid de... 175 3e-43
AF149416-1|AAF07272.2| 323|Homo sapiens 3-alpha hydroxysteroid ... 174 6e-43
AL355480-2|CAI22458.1| 147|Homo sapiens aldo-keto reductase fam... 174 9e-43
D26124-1|BAA05121.1| 306|Homo sapiens dihydrodiol dehydrogenase... 173 1e-42
DQ269985-1|ABB76132.1| 323|Homo sapiens type II 3a-hydroxystero... 173 1e-42
S68290-1|AAD14012.1| 320|Homo sapiens chlordecone reductase hom... 171 5e-42
AB045829-1|BAA99542.1| 323|Homo sapiens 3alpha-hydroxysteroid d... 168 6e-41
S68287-1|AAD14010.1| 323|Homo sapiens chlordecone reductase pro... 167 7e-41
D26125-1|BAA05122.1| 321|Homo sapiens 3 alpha-hydroxysteroid/di... 167 7e-41
AL355303-2|CAI14202.1| 323|Homo sapiens aldo-keto reductase fam... 167 7e-41
AB032163-1|BAA92893.1| 323|Homo sapiens dihydrodiol dehydrogena... 167 7e-41
AB031085-1|BAA92885.1| 323|Homo sapiens dihydrodiol dehydrogena... 167 7e-41
BC020744-1|AAH20744.1| 323|Homo sapiens aldo-keto reductase fam... 167 1e-40
M33375-1|AAA35658.1| 308|Homo sapiens protein ( Human chlordeco... 165 5e-40
AL713867-3|CAI16410.1| 247|Homo sapiens aldo-keto reductase fam... 146 1e-34
AB040822-1|BAC54567.1| 222|Homo sapiens aldo-keto reductase rel... 144 8e-34
AL391427-2|CAI14727.1| 302|Homo sapiens aldo-keto reductase fam... 132 3e-30
AL355303-1|CAI14201.1| 302|Homo sapiens aldo-keto reductase fam... 132 3e-30
BC101205-1|AAI01206.1| 129|Homo sapiens aldo-keto reductase fam... 116 2e-25
BC101204-1|AAI01205.1| 129|Homo sapiens aldo-keto reductase fam... 116 2e-25
AK131335-1|BAD18494.1| 129|Homo sapiens protein ( Homo sapiens ... 116 2e-25
AB037902-1|BAA92887.1| 130|Homo sapiens truncated aldo-keto red... 116 2e-25
AK058142-1|BAB71682.1| 146|Homo sapiens protein ( Homo sapiens ... 58 7e-08
AB028065-1|BAA88489.1| 67|Homo sapiens prostaglandin F synthas... 58 9e-08
AB037905-2|BAA92890.1| 45|Homo sapiens truncated aldo-keto red... 50 2e-05
AK131252-1|BAD18431.1| 415|Homo sapiens protein ( Homo sapiens ... 36 0.31
U33429-1|AAC50955.1| 367|Homo sapiens K+ channel beta 2 subunit... 34 1.3
L47665-1|AAC41926.1| 419|Homo sapiens K+ channel beta-subunit p... 34 1.3
CR542287-1|CAG47082.1| 353|Homo sapiens KCNAB2 protein. 34 1.3
BC130413-1|AAI30414.1| 367|Homo sapiens potassium voltage-gated... 34 1.3
BC126424-1|AAI26425.1| 367|Homo sapiens potassium voltage-gated... 34 1.3
BC110351-1|AAI10352.1| 395|Homo sapiens KCNAB2 protein protein. 34 1.3
AL035406-6|CAI19886.1| 253|Homo sapiens potassium voltage-gated... 34 1.3
AL035406-5|CAI19887.1| 254|Homo sapiens potassium voltage-gated... 34 1.3
AL035406-4|CAC08512.1| 367|Homo sapiens potassium voltage-gated... 34 1.3
AL035406-3|CAI19885.1| 353|Homo sapiens potassium voltage-gated... 34 1.3
AK075032-1|BAC11364.1| 524|Homo sapiens protein ( Homo sapiens ... 34 1.3
AF044253-1|AAB99859.1| 353|Homo sapiens potassium channel beta ... 34 1.3
AF029749-1|AAB84170.1| 367|Homo sapiens potassium channel beta ... 34 1.3
U72619-1|AAB61992.1| 22|Homo sapiens aldose reductase protein. 34 1.7
X83127-1|CAA58208.1| 401|Homo sapiens voltage gated potassium c... 33 2.2
U33428-1|AAC50953.1| 401|Homo sapiens K+ channel beta 1a subuni... 33 2.2
U16953-1|AAC50122.1| 408|Homo sapiens potassium channel beta3 s... 33 2.2
L39833-1|AAC37573.1| 408|Homo sapiens K+ channel beta-subunit p... 33 2.2
BC043166-1|AAH43166.1| 401|Homo sapiens potassium voltage-gated... 33 2.2
AF026947-1|AAC52104.1| 330|Homo sapiens aflatoxin aldehyde redu... 32 5.0
Y16675-1|CAA76347.1| 330|Homo sapiens aflatoxin B1-aldehyde red... 32 6.7
CR542264-1|CAG47060.1| 353|Homo sapiens KCNAB2 protein. 32 6.7
BT007347-1|AAP36011.1| 330|Homo sapiens aldo-keto reductase fam... 32 6.7
BC013996-1|AAH13996.1| 330|Homo sapiens AKR7A2 protein protein. 32 6.7
BC012171-1|AAH12171.1| 330|Homo sapiens AKR7A2 protein protein. 32 6.7
BC011586-1|AAH11586.1| 330|Homo sapiens AKR7A2 protein protein. 32 6.7
BC010852-1|AAH10852.1| 330|Homo sapiens AKR7A2 protein protein. 32 6.7
BC007352-1|AAH07352.2| 358|Homo sapiens AKR7A2 protein protein. 32 6.7
BC004111-1|AAH04111.3| 330|Homo sapiens AKR7A2 protein protein. 32 6.7
AL035413-8|CAB72321.1| 330|Homo sapiens aldo-keto reductase fam... 32 6.7
AJ278012-1|CAC79668.1| 259|Homo sapiens aflatoxin B1 aldehyde r... 31 8.8
>X15414-1|CAA33460.1| 316|Homo sapiens protein ( Human mRNA for
aldose reductase (EC 1.1.1.2). ).
Length = 316
Score = 250 bits (611), Expect = 1e-65
Identities = 122/243 (50%), Positives = 162/243 (66%), Gaps = 3/243 (1%)
Frame = +1
Query: 136 LSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQEG 315
L+NGAK+P++G+GTWKS PG+VT+AVK AID+GYRHI CA VY NE EVG AI+ K++E
Sbjct: 7 LNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLREQ 66
Query: 316 VVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTD 495
VVKRE+LFI SKLW T+H LV+GA + +L +L +DYLDLYLIHWP +K FP D
Sbjct: 67 VVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFPLD 126
Query: 496 ADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPGH*PGRMP 675
G + SD + +DTW A+E LV GLV+++G+SNFN Q++ IL+ +K + P
Sbjct: 127 ESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLK--YKPAVNQ 184
Query: 676 SVFKPXAIEAVLRRP*YYDNGVLPRW---GXPDRPWAKPGDPHLMEDPKLKEIADRLGKX 846
P + L + V+ + G PDRPWAKP DP L+EDP++K IA + K
Sbjct: 185 IECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAKHNKT 244
Query: 847 AAQ 855
AQ
Sbjct: 245 TAQ 247
Score = 49.6 bits (113), Expect = 3e-05
Identities = 17/32 (53%), Positives = 25/32 (78%)
Frame = +2
Query: 659 NQVECHPYLNXKRLKQFCEDRDIMITXYSPXG 754
NQ+ECHPYL ++L Q+C+ + I++T YSP G
Sbjct: 183 NQIECHPYLTQEKLIQYCQSKGIVVTAYSPLG 214
>M59783-1|AAA51712.1| 316|Homo sapiens aldose reductase protein.
Length = 316
Score = 250 bits (611), Expect = 1e-65
Identities = 122/243 (50%), Positives = 162/243 (66%), Gaps = 3/243 (1%)
Frame = +1
Query: 136 LSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQEG 315
L+NGAK+P++G+GTWKS PG+VT+AVK AID+GYRHI CA VY NE EVG AI+ K++E
Sbjct: 7 LNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLREQ 66
Query: 316 VVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTD 495
VVKRE+LFI SKLW T+H LV+GA + +L +L +DYLDLYLIHWP +K FP D
Sbjct: 67 VVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFPLD 126
Query: 496 ADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPGH*PGRMP 675
G + SD + +DTW A+E LV GLV+++G+SNFN Q++ IL+ +K + P
Sbjct: 127 ESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLK--YKPAVNQ 184
Query: 676 SVFKPXAIEAVLRRP*YYDNGVLPRW---GXPDRPWAKPGDPHLMEDPKLKEIADRLGKX 846
P + L + V+ + G PDRPWAKP DP L+EDP++K IA + K
Sbjct: 185 IECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAKHNKT 244
Query: 847 AAQ 855
AQ
Sbjct: 245 TAQ 247
Score = 49.6 bits (113), Expect = 3e-05
Identities = 17/32 (53%), Positives = 25/32 (78%)
Frame = +2
Query: 659 NQVECHPYLNXKRLKQFCEDRDIMITXYSPXG 754
NQ+ECHPYL ++L Q+C+ + I++T YSP G
Sbjct: 183 NQIECHPYLTQEKLIQYCQSKGIVVTAYSPLG 214
>M34720-1|AAA35560.1| 316|Homo sapiens protein ( Human aldose
reductase mRNA, complete cds. ).
Length = 316
Score = 250 bits (611), Expect = 1e-65
Identities = 122/243 (50%), Positives = 162/243 (66%), Gaps = 3/243 (1%)
Frame = +1
Query: 136 LSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQEG 315
L+NGAK+P++G+GTWKS PG+VT+AVK AID+GYRHI CA VY NE EVG AI+ K++E
Sbjct: 7 LNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLREQ 66
Query: 316 VVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTD 495
VVKRE+LFI SKLW T+H LV+GA + +L +L +DYLDLYLIHWP +K FP D
Sbjct: 67 VVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFPLD 126
Query: 496 ADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPGH*PGRMP 675
G + SD + +DTW A+E LV GLV+++G+SNFN Q++ IL+ +K + P
Sbjct: 127 ESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLK--YKPAVNQ 184
Query: 676 SVFKPXAIEAVLRRP*YYDNGVLPRW---GXPDRPWAKPGDPHLMEDPKLKEIADRLGKX 846
P + L + V+ + G PDRPWAKP DP L+EDP++K IA + K
Sbjct: 185 IECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAKHNKT 244
Query: 847 AAQ 855
AQ
Sbjct: 245 TAQ 247
Score = 49.6 bits (113), Expect = 3e-05
Identities = 17/32 (53%), Positives = 25/32 (78%)
Frame = +2
Query: 659 NQVECHPYLNXKRLKQFCEDRDIMITXYSPXG 754
NQ+ECHPYL ++L Q+C+ + I++T YSP G
Sbjct: 183 NQIECHPYLTQEKLIQYCQSKGIVVTAYSPLG 214
>J05474-1|AAA51715.1| 316|Homo sapiens aldose reductase protein.
Length = 316
Score = 250 bits (611), Expect = 1e-65
Identities = 122/243 (50%), Positives = 162/243 (66%), Gaps = 3/243 (1%)
Frame = +1
Query: 136 LSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQEG 315
L+NGAK+P++G+GTWKS PG+VT+AVK AID+GYRHI CA VY NE EVG AI+ K++E
Sbjct: 7 LNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLREQ 66
Query: 316 VVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTD 495
VVKRE+LFI SKLW T+H LV+GA + +L +L +DYLDLYLIHWP +K FP D
Sbjct: 67 VVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFPLD 126
Query: 496 ADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPGH*PGRMP 675
G + SD + +DTW A+E LV GLV+++G+SNFN Q++ IL+ +K + P
Sbjct: 127 ESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLK--YKPAVNQ 184
Query: 676 SVFKPXAIEAVLRRP*YYDNGVLPRW---GXPDRPWAKPGDPHLMEDPKLKEIADRLGKX 846
P + L + V+ + G PDRPWAKP DP L+EDP++K IA + K
Sbjct: 185 IECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAKHNKT 244
Query: 847 AAQ 855
AQ
Sbjct: 245 TAQ 247
Score = 49.6 bits (113), Expect = 3e-05
Identities = 17/32 (53%), Positives = 25/32 (78%)
Frame = +2
Query: 659 NQVECHPYLNXKRLKQFCEDRDIMITXYSPXG 754
NQ+ECHPYL ++L Q+C+ + I++T YSP G
Sbjct: 183 NQIECHPYLTQEKLIQYCQSKGIVVTAYSPLG 214
>J05017-1|AAA51714.1| 316|Homo sapiens ALDR1 protein.
Length = 316
Score = 250 bits (611), Expect = 1e-65
Identities = 122/243 (50%), Positives = 162/243 (66%), Gaps = 3/243 (1%)
Frame = +1
Query: 136 LSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQEG 315
L+NGAK+P++G+GTWKS PG+VT+AVK AID+GYRHI CA VY NE EVG AI+ K++E
Sbjct: 7 LNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLREQ 66
Query: 316 VVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTD 495
VVKRE+LFI SKLW T+H LV+GA + +L +L +DYLDLYLIHWP +K FP D
Sbjct: 67 VVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFPLD 126
Query: 496 ADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPGH*PGRMP 675
G + SD + +DTW A+E LV GLV+++G+SNFN Q++ IL+ +K + P
Sbjct: 127 ESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLK--YKPAVNQ 184
Query: 676 SVFKPXAIEAVLRRP*YYDNGVLPRW---GXPDRPWAKPGDPHLMEDPKLKEIADRLGKX 846
P + L + V+ + G PDRPWAKP DP L+EDP++K IA + K
Sbjct: 185 IECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAKHNKT 244
Query: 847 AAQ 855
AQ
Sbjct: 245 TAQ 247
Score = 49.6 bits (113), Expect = 3e-05
Identities = 17/32 (53%), Positives = 25/32 (78%)
Frame = +2
Query: 659 NQVECHPYLNXKRLKQFCEDRDIMITXYSPXG 754
NQ+ECHPYL ++L Q+C+ + I++T YSP G
Sbjct: 183 NQIECHPYLTQEKLIQYCQSKGIVVTAYSPLG 214
>J04795-1|AAA51713.1| 316|Homo sapiens ALDR1 protein.
Length = 316
Score = 250 bits (611), Expect = 1e-65
Identities = 122/243 (50%), Positives = 162/243 (66%), Gaps = 3/243 (1%)
Frame = +1
Query: 136 LSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQEG 315
L+NGAK+P++G+GTWKS PG+VT+AVK AID+GYRHI CA VY NE EVG AI+ K++E
Sbjct: 7 LNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLREQ 66
Query: 316 VVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTD 495
VVKRE+LFI SKLW T+H LV+GA + +L +L +DYLDLYLIHWP +K FP D
Sbjct: 67 VVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFPLD 126
Query: 496 ADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPGH*PGRMP 675
G + SD + +DTW A+E LV GLV+++G+SNFN Q++ IL+ +K + P
Sbjct: 127 ESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLK--YKPAVNQ 184
Query: 676 SVFKPXAIEAVLRRP*YYDNGVLPRW---GXPDRPWAKPGDPHLMEDPKLKEIADRLGKX 846
P + L + V+ + G PDRPWAKP DP L+EDP++K IA + K
Sbjct: 185 IECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAKHNKT 244
Query: 847 AAQ 855
AQ
Sbjct: 245 TAQ 247
Score = 49.6 bits (113), Expect = 3e-05
Identities = 17/32 (53%), Positives = 25/32 (78%)
Frame = +2
Query: 659 NQVECHPYLNXKRLKQFCEDRDIMITXYSPXG 754
NQ+ECHPYL ++L Q+C+ + I++T YSP G
Sbjct: 183 NQIECHPYLTQEKLIQYCQSKGIVVTAYSPLG 214
>BT019859-1|AAV38662.1| 316|Homo sapiens aldo-keto reductase family
1, member B1 (aldose reductase) protein.
Length = 316
Score = 250 bits (611), Expect = 1e-65
Identities = 122/243 (50%), Positives = 162/243 (66%), Gaps = 3/243 (1%)
Frame = +1
Query: 136 LSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQEG 315
L+NGAK+P++G+GTWKS PG+VT+AVK AID+GYRHI CA VY NE EVG AI+ K++E
Sbjct: 7 LNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLREQ 66
Query: 316 VVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTD 495
VVKRE+LFI SKLW T+H LV+GA + +L +L +DYLDLYLIHWP +K FP D
Sbjct: 67 VVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFPLD 126
Query: 496 ADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPGH*PGRMP 675
G + SD + +DTW A+E LV GLV+++G+SNFN Q++ IL+ +K + P
Sbjct: 127 ESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLK--YKPAVNQ 184
Query: 676 SVFKPXAIEAVLRRP*YYDNGVLPRW---GXPDRPWAKPGDPHLMEDPKLKEIADRLGKX 846
P + L + V+ + G PDRPWAKP DP L+EDP++K IA + K
Sbjct: 185 IECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAKHNKT 244
Query: 847 AAQ 855
AQ
Sbjct: 245 TAQ 247
Score = 49.6 bits (113), Expect = 3e-05
Identities = 17/32 (53%), Positives = 25/32 (78%)
Frame = +2
Query: 659 NQVECHPYLNXKRLKQFCEDRDIMITXYSPXG 754
NQ+ECHPYL ++L Q+C+ + I++T YSP G
Sbjct: 183 NQIECHPYLTQEKLIQYCQSKGIVVTAYSPLG 214
>BC010391-1|AAH10391.1| 316|Homo sapiens aldo-keto reductase family
1, member B1 (aldose reductase) protein.
Length = 316
Score = 250 bits (611), Expect = 1e-65
Identities = 122/243 (50%), Positives = 162/243 (66%), Gaps = 3/243 (1%)
Frame = +1
Query: 136 LSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQEG 315
L+NGAK+P++G+GTWKS PG+VT+AVK AID+GYRHI CA VY NE EVG AI+ K++E
Sbjct: 7 LNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLREQ 66
Query: 316 VVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTD 495
VVKRE+LFI SKLW T+H LV+GA + +L +L +DYLDLYLIHWP +K FP D
Sbjct: 67 VVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFPLD 126
Query: 496 ADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPGH*PGRMP 675
G + SD + +DTW A+E LV GLV+++G+SNFN Q++ IL+ +K + P
Sbjct: 127 ESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLK--YKPAVNQ 184
Query: 676 SVFKPXAIEAVLRRP*YYDNGVLPRW---GXPDRPWAKPGDPHLMEDPKLKEIADRLGKX 846
P + L + V+ + G PDRPWAKP DP L+EDP++K IA + K
Sbjct: 185 IECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAKHNKT 244
Query: 847 AAQ 855
AQ
Sbjct: 245 TAQ 247
Score = 49.6 bits (113), Expect = 3e-05
Identities = 17/32 (53%), Positives = 25/32 (78%)
Frame = +2
Query: 659 NQVECHPYLNXKRLKQFCEDRDIMITXYSPXG 754
NQ+ECHPYL ++L Q+C+ + I++T YSP G
Sbjct: 183 NQIECHPYLTQEKLIQYCQSKGIVVTAYSPLG 214
>BC000260-1|AAH00260.1| 316|Homo sapiens aldo-keto reductase family
1, member B1 (aldose reductase) protein.
Length = 316
Score = 250 bits (611), Expect = 1e-65
Identities = 122/243 (50%), Positives = 162/243 (66%), Gaps = 3/243 (1%)
Frame = +1
Query: 136 LSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQEG 315
L+NGAK+P++G+GTWKS PG+VT+AVK AID+GYRHI CA VY NE EVG AI+ K++E
Sbjct: 7 LNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLREQ 66
Query: 316 VVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTD 495
VVKRE+LFI SKLW T+H LV+GA + +L +L +DYLDLYLIHWP +K FP D
Sbjct: 67 VVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFPLD 126
Query: 496 ADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPGH*PGRMP 675
G + SD + +DTW A+E LV GLV+++G+SNFN Q++ IL+ +K + P
Sbjct: 127 ESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLK--YKPAVNQ 184
Query: 676 SVFKPXAIEAVLRRP*YYDNGVLPRW---GXPDRPWAKPGDPHLMEDPKLKEIADRLGKX 846
P + L + V+ + G PDRPWAKP DP L+EDP++K IA + K
Sbjct: 185 IECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAKHNKT 244
Query: 847 AAQ 855
AQ
Sbjct: 245 TAQ 247
Score = 49.6 bits (113), Expect = 3e-05
Identities = 17/32 (53%), Positives = 25/32 (78%)
Frame = +2
Query: 659 NQVECHPYLNXKRLKQFCEDRDIMITXYSPXG 754
NQ+ECHPYL ++L Q+C+ + I++T YSP G
Sbjct: 183 NQIECHPYLTQEKLIQYCQSKGIVVTAYSPLG 214
>AF328729-1|AAN09721.1| 316|Homo sapiens CTCL tumor antigen
HD-CL-07 protein.
Length = 316
Score = 250 bits (611), Expect = 1e-65
Identities = 122/243 (50%), Positives = 162/243 (66%), Gaps = 3/243 (1%)
Frame = +1
Query: 136 LSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQEG 315
L+NGAK+P++G+GTWKS PG+VT+AVK AID+GYRHI CA VY NE EVG AI+ K++E
Sbjct: 7 LNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLREQ 66
Query: 316 VVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTD 495
VVKRE+LFI SKLW T+H LV+GA + +L +L +DYLDLYLIHWP +K FP D
Sbjct: 67 VVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFPLD 126
Query: 496 ADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPGH*PGRMP 675
G + SD + +DTW A+E LV GLV+++G+SNFN Q++ IL+ +K + P
Sbjct: 127 ESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLK--YKPAVNQ 184
Query: 676 SVFKPXAIEAVLRRP*YYDNGVLPRW---GXPDRPWAKPGDPHLMEDPKLKEIADRLGKX 846
P + L + V+ + G PDRPWAKP DP L+EDP++K IA + K
Sbjct: 185 IECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAKHNKT 244
Query: 847 AAQ 855
AQ
Sbjct: 245 TAQ 247
Score = 49.6 bits (113), Expect = 3e-05
Identities = 17/32 (53%), Positives = 25/32 (78%)
Frame = +2
Query: 659 NQVECHPYLNXKRLKQFCEDRDIMITXYSPXG 754
NQ+ECHPYL ++L Q+C+ + I++T YSP G
Sbjct: 183 NQIECHPYLTQEKLIQYCQSKGIVVTAYSPLG 214
>AF032455-1|AAB88851.1| 316|Homo sapiens aldose reductase protein.
Length = 316
Score = 250 bits (611), Expect = 1e-65
Identities = 122/243 (50%), Positives = 162/243 (66%), Gaps = 3/243 (1%)
Frame = +1
Query: 136 LSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQEG 315
L+NGAK+P++G+GTWKS PG+VT+AVK AID+GYRHI CA VY NE EVG AI+ K++E
Sbjct: 7 LNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLREQ 66
Query: 316 VVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTD 495
VVKRE+LFI SKLW T+H LV+GA + +L +L +DYLDLYLIHWP +K FP D
Sbjct: 67 VVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFPLD 126
Query: 496 ADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPGH*PGRMP 675
G + SD + +DTW A+E LV GLV+++G+SNFN Q++ IL+ +K + P
Sbjct: 127 ESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLK--YKPAVNQ 184
Query: 676 SVFKPXAIEAVLRRP*YYDNGVLPRW---GXPDRPWAKPGDPHLMEDPKLKEIADRLGKX 846
P + L + V+ + G PDRPWAKP DP L+EDP++K IA + K
Sbjct: 185 IECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAKHNKT 244
Query: 847 AAQ 855
AQ
Sbjct: 245 TAQ 247
Score = 49.6 bits (113), Expect = 3e-05
Identities = 17/32 (53%), Positives = 25/32 (78%)
Frame = +2
Query: 659 NQVECHPYLNXKRLKQFCEDRDIMITXYSPXG 754
NQ+ECHPYL ++L Q+C+ + I++T YSP G
Sbjct: 183 NQIECHPYLTQEKLIQYCQSKGIVVTAYSPLG 214
>AB209796-1|BAD93033.1| 260|Homo sapiens aldo-keto reductase family
1, member B1 variant protein.
Length = 260
Score = 250 bits (611), Expect = 1e-65
Identities = 122/243 (50%), Positives = 162/243 (66%), Gaps = 3/243 (1%)
Frame = +1
Query: 136 LSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQEG 315
L+NGAK+P++G+GTWKS PG+VT+AVK AID+GYRHI CA VY NE EVG AI+ K++E
Sbjct: 4 LNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLREQ 63
Query: 316 VVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTD 495
VVKRE+LFI SKLW T+H LV+GA + +L +L +DYLDLYLIHWP +K FP D
Sbjct: 64 VVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFPLD 123
Query: 496 ADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPGH*PGRMP 675
G + SD + +DTW A+E LV GLV+++G+SNFN Q++ IL+ +K + P
Sbjct: 124 ESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLK--YKPAVNQ 181
Query: 676 SVFKPXAIEAVLRRP*YYDNGVLPRW---GXPDRPWAKPGDPHLMEDPKLKEIADRLGKX 846
P + L + V+ + G PDRPWAKP DP L+EDP++K IA + K
Sbjct: 182 IECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAKHNKT 241
Query: 847 AAQ 855
AQ
Sbjct: 242 TAQ 244
Score = 49.6 bits (113), Expect = 3e-05
Identities = 17/32 (53%), Positives = 25/32 (78%)
Frame = +2
Query: 659 NQVECHPYLNXKRLKQFCEDRDIMITXYSPXG 754
NQ+ECHPYL ++L Q+C+ + I++T YSP G
Sbjct: 180 NQIECHPYLTQEKLIQYCQSKGIVVTAYSPLG 211
>CR542203-1|CAG47000.1| 316|Homo sapiens AKR1B1 protein.
Length = 316
Score = 249 bits (609), Expect = 2e-65
Identities = 122/243 (50%), Positives = 162/243 (66%), Gaps = 3/243 (1%)
Frame = +1
Query: 136 LSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQEG 315
L+NGAK+P++G+GTWKS PG+VT+AVK AID+GYRHI CA VY NE EVG AI+ K++E
Sbjct: 7 LNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLREQ 66
Query: 316 VVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTD 495
VVKRE+LFI SKLW T+H LV+GA + +L +L +DYLDLYLIHWP +K FP D
Sbjct: 67 VVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPIGFKPGKEFFPLD 126
Query: 496 ADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPGH*PGRMP 675
G + SD + +DTW A+E LV GLV+++G+SNFN Q++ IL+ +K + P
Sbjct: 127 ESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLK--YKPAVNQ 184
Query: 676 SVFKPXAIEAVLRRP*YYDNGVLPRW---GXPDRPWAKPGDPHLMEDPKLKEIADRLGKX 846
P + L + V+ + G PDRPWAKP DP L+EDP++K IA + K
Sbjct: 185 IECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAKHNKT 244
Query: 847 AAQ 855
AQ
Sbjct: 245 TAQ 247
Score = 49.6 bits (113), Expect = 3e-05
Identities = 17/32 (53%), Positives = 25/32 (78%)
Frame = +2
Query: 659 NQVECHPYLNXKRLKQFCEDRDIMITXYSPXG 754
NQ+ECHPYL ++L Q+C+ + I++T YSP G
Sbjct: 183 NQIECHPYLTQEKLIQYCQSKGIVVTAYSPLG 214
>CR450351-1|CAG29347.1| 316|Homo sapiens AKR1B1 protein.
Length = 316
Score = 248 bits (607), Expect = 4e-65
Identities = 121/243 (49%), Positives = 161/243 (66%), Gaps = 3/243 (1%)
Frame = +1
Query: 136 LSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQEG 315
L+NGAK+P++G+GTWKS PG+VT+AVK AID+GYRHI CA VY NE EVG AI+ K++E
Sbjct: 7 LNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLREQ 66
Query: 316 VVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTD 495
VVKRE+LFI SKLW T+H LV+GA + +L +L +DYLDLYLIHWP ++ FP D
Sbjct: 67 VVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFRPGKEFFPLD 126
Query: 496 ADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPGH*PGRMP 675
G + SD + +DTW A+E LV GLV+++G+SNFN Q++ IL +K + P
Sbjct: 127 ESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILSKPGLK--YKPAVNQ 184
Query: 676 SVFKPXAIEAVLRRP*YYDNGVLPRW---GXPDRPWAKPGDPHLMEDPKLKEIADRLGKX 846
P + L + V+ + G PDRPWAKP DP L+EDP++K IA + K
Sbjct: 185 IECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAKHNKT 244
Query: 847 AAQ 855
AQ
Sbjct: 245 TAQ 247
Score = 49.6 bits (113), Expect = 3e-05
Identities = 17/32 (53%), Positives = 25/32 (78%)
Frame = +2
Query: 659 NQVECHPYLNXKRLKQFCEDRDIMITXYSPXG 754
NQ+ECHPYL ++L Q+C+ + I++T YSP G
Sbjct: 183 NQIECHPYLTQEKLIQYCQSKGIVVTAYSPLG 214
>BC005387-1|AAH05387.1| 316|Homo sapiens aldo-keto reductase family
1, member B1 (aldose reductase) protein.
Length = 316
Score = 244 bits (597), Expect = 7e-64
Identities = 121/243 (49%), Positives = 161/243 (66%), Gaps = 3/243 (1%)
Frame = +1
Query: 136 LSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQEG 315
L+NGAK+P++G+GTWKS PG+VT+AVK AID+GYRHI CA VY NE EVG AI+ K++E
Sbjct: 7 LNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLREQ 66
Query: 316 VVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTD 495
VVKRE+LFI SKLW T+H LV+GA + +L +L +DYLDLYLIHWP +K FP D
Sbjct: 67 VVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFPLD 126
Query: 496 ADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPGH*PGRMP 675
G + SD + +DT A+E LV GLV+++G+SNFN Q++ IL+ +K + P
Sbjct: 127 ESGNVVPSDTNILDTRAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLK--YKPAVNQ 184
Query: 676 SVFKPXAIEAVLRRP*YYDNGVLPRW---GXPDRPWAKPGDPHLMEDPKLKEIADRLGKX 846
P + L + V+ + G PDRPWAKP DP L+EDP++K IA + K
Sbjct: 185 IECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAKHNKT 244
Query: 847 AAQ 855
AQ
Sbjct: 245 TAQ 247
Score = 49.6 bits (113), Expect = 3e-05
Identities = 17/32 (53%), Positives = 25/32 (78%)
Frame = +2
Query: 659 NQVECHPYLNXKRLKQFCEDRDIMITXYSPXG 754
NQ+ECHPYL ++L Q+C+ + I++T YSP G
Sbjct: 183 NQIECHPYLTQEKLIQYCQSKGIVVTAYSPLG 214
>U37100-1|AAC17469.1| 316|Homo sapiens aldose reductase-like
peptide protein.
Length = 316
Score = 240 bits (588), Expect = 9e-63
Identities = 122/243 (50%), Positives = 159/243 (65%), Gaps = 3/243 (1%)
Frame = +1
Query: 136 LSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQEG 315
LS AK+P++G+GTWKS G+V +AVK AID GYRHI CA+VY NE EVGEAI+ KIQE
Sbjct: 7 LSTKAKMPIVGLGTWKSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEKIQEK 66
Query: 316 VVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTD 495
VKREDLFI SKLW TF LVR A E +L++L + YLD+YLIHWPQ +K D +FP D
Sbjct: 67 AVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGDDLFPKD 126
Query: 496 ADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPGH*PGRMP 675
G ++D W+A+E LV GLV++LGVSNF+ Q++++L+ +K + P
Sbjct: 127 DKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLK--YKPVTNQ 184
Query: 676 SVFKPXAIEAVLRRP*YYDNGVLPRW---GXPDRPWAKPGDPHLMEDPKLKEIADRLGKX 846
P + L + + + + G PDRPWAKP DP L+EDPK+KEIA + K
Sbjct: 185 VECHPYLTQEKLIQYCHSKGITVTAYSPLGSPDRPWAKPEDPSLLEDPKIKEIAAKHKKT 244
Query: 847 AAQ 855
AAQ
Sbjct: 245 AAQ 247
Score = 52.0 bits (119), Expect = 6e-06
Identities = 20/34 (58%), Positives = 25/34 (73%)
Frame = +2
Query: 653 VTNQVECHPYLNXKRLKQFCEDRDIMITXYSPXG 754
VTNQVECHPYL ++L Q+C + I +T YSP G
Sbjct: 181 VTNQVECHPYLTQEKLIQYCHSKGITVTAYSPLG 214
>CR541801-1|CAG46600.1| 316|Homo sapiens AKR1B10 protein.
Length = 316
Score = 240 bits (588), Expect = 9e-63
Identities = 122/243 (50%), Positives = 159/243 (65%), Gaps = 3/243 (1%)
Frame = +1
Query: 136 LSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQEG 315
LS AK+P++G+GTWKS G+V +AVK AID GYRHI CA+VY NE EVGEAI+ KIQE
Sbjct: 7 LSTKAKMPIVGLGTWKSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEKIQEK 66
Query: 316 VVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTD 495
VKREDLFI SKLW TF LVR A E +L++L + YLD+YLIHWPQ +K D +FP D
Sbjct: 67 AVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGDDLFPKD 126
Query: 496 ADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPGH*PGRMP 675
G ++D W+A+E LV GLV++LGVSNF+ Q++++L+ +K + P
Sbjct: 127 DKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLK--YKPVTNQ 184
Query: 676 SVFKPXAIEAVLRRP*YYDNGVLPRW---GXPDRPWAKPGDPHLMEDPKLKEIADRLGKX 846
P + L + + + + G PDRPWAKP DP L+EDPK+KEIA + K
Sbjct: 185 VECHPYLTQEKLIQYCHSKGITVTAYSPLGSPDRPWAKPEDPSLLEDPKIKEIAAKHKKT 244
Query: 847 AAQ 855
AAQ
Sbjct: 245 AAQ 247
Score = 52.0 bits (119), Expect = 6e-06
Identities = 20/34 (58%), Positives = 25/34 (73%)
Frame = +2
Query: 653 VTNQVECHPYLNXKRLKQFCEDRDIMITXYSPXG 754
VTNQVECHPYL ++L Q+C + I +T YSP G
Sbjct: 181 VTNQVECHPYLTQEKLIQYCHSKGITVTAYSPLG 214
>BT006794-1|AAP35440.1| 316|Homo sapiens aldo-keto reductase family
1, member B10 (aldose reductase) protein.
Length = 316
Score = 240 bits (588), Expect = 9e-63
Identities = 122/243 (50%), Positives = 159/243 (65%), Gaps = 3/243 (1%)
Frame = +1
Query: 136 LSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQEG 315
LS AK+P++G+GTWKS G+V +AVK AID GYRHI CA+VY NE EVGEAI+ KIQE
Sbjct: 7 LSTKAKMPIVGLGTWKSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEKIQEK 66
Query: 316 VVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTD 495
VKREDLFI SKLW TF LVR A E +L++L + YLD+YLIHWPQ +K D +FP D
Sbjct: 67 AVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGDDLFPKD 126
Query: 496 ADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPGH*PGRMP 675
G ++D W+A+E LV GLV++LGVSNF+ Q++++L+ +K + P
Sbjct: 127 DKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLK--YKPVTNQ 184
Query: 676 SVFKPXAIEAVLRRP*YYDNGVLPRW---GXPDRPWAKPGDPHLMEDPKLKEIADRLGKX 846
P + L + + + + G PDRPWAKP DP L+EDPK+KEIA + K
Sbjct: 185 VECHPYLTQEKLIQYCHSKGITVTAYSPLGSPDRPWAKPEDPSLLEDPKIKEIAAKHKKT 244
Query: 847 AAQ 855
AAQ
Sbjct: 245 AAQ 247
Score = 52.0 bits (119), Expect = 6e-06
Identities = 20/34 (58%), Positives = 25/34 (73%)
Frame = +2
Query: 653 VTNQVECHPYLNXKRLKQFCEDRDIMITXYSPXG 754
VTNQVECHPYL ++L Q+C + I +T YSP G
Sbjct: 181 VTNQVECHPYLTQEKLIQYCHSKGITVTAYSPLG 214
>BC008837-1|AAH08837.1| 316|Homo sapiens aldo-keto reductase family
1, member B10 (aldose reductase) protein.
Length = 316
Score = 240 bits (588), Expect = 9e-63
Identities = 122/243 (50%), Positives = 159/243 (65%), Gaps = 3/243 (1%)
Frame = +1
Query: 136 LSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQEG 315
LS AK+P++G+GTWKS G+V +AVK AID GYRHI CA+VY NE EVGEAI+ KIQE
Sbjct: 7 LSTKAKMPIVGLGTWKSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEKIQEK 66
Query: 316 VVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTD 495
VKREDLFI SKLW TF LVR A E +L++L + YLD+YLIHWPQ +K D +FP D
Sbjct: 67 AVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGDDLFPKD 126
Query: 496 ADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPGH*PGRMP 675
G ++D W+A+E LV GLV++LGVSNF+ Q++++L+ +K + P
Sbjct: 127 DKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLK--YKPVTNQ 184
Query: 676 SVFKPXAIEAVLRRP*YYDNGVLPRW---GXPDRPWAKPGDPHLMEDPKLKEIADRLGKX 846
P + L + + + + G PDRPWAKP DP L+EDPK+KEIA + K
Sbjct: 185 VECHPYLTQEKLIQYCHSKGITVTAYSPLGSPDRPWAKPEDPSLLEDPKIKEIAAKHKKT 244
Query: 847 AAQ 855
AAQ
Sbjct: 245 AAQ 247
Score = 52.0 bits (119), Expect = 6e-06
Identities = 20/34 (58%), Positives = 25/34 (73%)
Frame = +2
Query: 653 VTNQVECHPYLNXKRLKQFCEDRDIMITXYSPXG 754
VTNQVECHPYL ++L Q+C + I +T YSP G
Sbjct: 181 VTNQVECHPYLTQEKLIQYCHSKGITVTAYSPLG 214
>AF052577-1|AAC36465.1| 316|Homo sapiens aldo-keto reductase
protein.
Length = 316
Score = 240 bits (588), Expect = 9e-63
Identities = 122/243 (50%), Positives = 159/243 (65%), Gaps = 3/243 (1%)
Frame = +1
Query: 136 LSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQEG 315
LS AK+P++G+GTWKS G+V +AVK AID GYRHI CA+VY NE EVGEAI+ KIQE
Sbjct: 7 LSTKAKMPIVGLGTWKSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEKIQEK 66
Query: 316 VVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTD 495
VKREDLFI SKLW TF LVR A E +L++L + YLD+YLIHWPQ +K D +FP D
Sbjct: 67 AVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGDDLFPKD 126
Query: 496 ADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPGH*PGRMP 675
G ++D W+A+E LV GLV++LGVSNF+ Q++++L+ +K + P
Sbjct: 127 DKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLK--YKPVTNQ 184
Query: 676 SVFKPXAIEAVLRRP*YYDNGVLPRW---GXPDRPWAKPGDPHLMEDPKLKEIADRLGKX 846
P + L + + + + G PDRPWAKP DP L+EDPK+KEIA + K
Sbjct: 185 VECHPYLTQEKLIQYCHSKGITVTAYSPLGSPDRPWAKPEDPSLLEDPKIKEIAAKHKKT 244
Query: 847 AAQ 855
AAQ
Sbjct: 245 AAQ 247
Score = 52.0 bits (119), Expect = 6e-06
Identities = 20/34 (58%), Positives = 25/34 (73%)
Frame = +2
Query: 653 VTNQVECHPYLNXKRLKQFCEDRDIMITXYSPXG 754
VTNQVECHPYL ++L Q+C + I +T YSP G
Sbjct: 181 VTNQVECHPYLTQEKLIQYCHSKGITVTAYSPLG 214
>AF524864-1|AAO13380.1| 316|Homo sapiens aldo-ketoreductase
protein.
Length = 316
Score = 237 bits (581), Expect = 6e-62
Identities = 121/243 (49%), Positives = 158/243 (65%), Gaps = 3/243 (1%)
Frame = +1
Query: 136 LSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQEG 315
LS AK+P++G+GTWKS G+V +AVK AID GYRHI CA+VY NE EVGEAI+ KIQE
Sbjct: 7 LSTKAKMPIVGLGTWKSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEKIQEK 66
Query: 316 VVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTD 495
VKREDLFI SKLW TF LVR A E +L++ + YLD+YLIHWPQ +K D +FP D
Sbjct: 67 AVKREDLFIASKLWPTFFERPLVRKAFEKTLKDPKLSYLDVYLIHWPQGFKSGDDLFPKD 126
Query: 496 ADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPGH*PGRMP 675
G ++D W+A+E LV GLV++LGVSNF+ Q++++L+ +K + P
Sbjct: 127 DKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLK--YKPVTNQ 184
Query: 676 SVFKPXAIEAVLRRP*YYDNGVLPRW---GXPDRPWAKPGDPHLMEDPKLKEIADRLGKX 846
P + L + + + + G PDRPWAKP DP L+EDPK+KEIA + K
Sbjct: 185 VECHPYLTQEKLIQYCHSKGITVTAYSPLGSPDRPWAKPEDPSLLEDPKIKEIAAKHKKT 244
Query: 847 AAQ 855
AAQ
Sbjct: 245 AAQ 247
Score = 52.0 bits (119), Expect = 6e-06
Identities = 20/34 (58%), Positives = 25/34 (73%)
Frame = +2
Query: 653 VTNQVECHPYLNXKRLKQFCEDRDIMITXYSPXG 754
VTNQVECHPYL ++L Q+C + I +T YSP G
Sbjct: 181 VTNQVECHPYLTQEKLIQYCHSKGITVTAYSPLG 214
>J04794-1|AAA51711.1| 325|Homo sapiens ALDR1 protein.
Length = 325
Score = 227 bits (555), Expect = 9e-59
Identities = 112/241 (46%), Positives = 152/241 (63%), Gaps = 1/241 (0%)
Frame = +1
Query: 136 LSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQEG 315
L G K+P+IG+GTWKS+PG+V AVK A+ +GYRHI CA +YGNE E+GEA+K + G
Sbjct: 8 LHTGQKMPLIGLGTWKSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALKEDVGPG 67
Query: 316 -VVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPT 492
V RE+LF+TSKLWNT H P+ V AL +L +L ++YLDLYL+HWP A++ D FP
Sbjct: 68 KAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDNPFPK 127
Query: 493 DADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPGH*PGRM 672
+ADG I + Y +TWKALE LV GLV++LG+SNFNS+Q+ IL ASV+P
Sbjct: 128 NADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASVRPAVLQVEC 187
Query: 673 PSVFKPXAIEAVLRRP*YYDNGVLPRWGXPDRPWAKPGDPHLMEDPKLKEIADRLGKXAA 852
+ A + P G DR W P +P L+E+P + +A++ G+ A
Sbjct: 188 HPYLAQNELIAHCQARGLEVTAYSP-LGSSDRAWRDPDEPVLLEEPVVLALAEKYGRSPA 246
Query: 853 Q 855
Q
Sbjct: 247 Q 247
Score = 39.9 bits (89), Expect = 0.025
Identities = 16/31 (51%), Positives = 19/31 (61%)
Frame = +2
Query: 662 QVECHPYLNXKRLKQFCEDRDIMITXYSPXG 754
QVECHPYL L C+ R + +T YSP G
Sbjct: 184 QVECHPYLAQNELIAHCQARGLEVTAYSPLG 214
>CR457010-1|CAG33291.1| 325|Homo sapiens AKR1A1 protein.
Length = 325
Score = 227 bits (555), Expect = 9e-59
Identities = 112/241 (46%), Positives = 152/241 (63%), Gaps = 1/241 (0%)
Frame = +1
Query: 136 LSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQEG 315
L G K+P+IG+GTWKS+PG+V AVK A+ +GYRHI CA +YGNE E+GEA+K + G
Sbjct: 8 LHTGQKMPLIGLGTWKSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALKEDVGPG 67
Query: 316 -VVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPT 492
V RE+LF+TSKLWNT H P+ V AL +L +L ++YLDLYL+HWP A++ D FP
Sbjct: 68 KAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDNPFPK 127
Query: 493 DADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPGH*PGRM 672
+ADG I + Y +TWKALE LV GLV++LG+SNFNS+Q+ IL ASV+P
Sbjct: 128 NADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASVRPAVLQVEC 187
Query: 673 PSVFKPXAIEAVLRRP*YYDNGVLPRWGXPDRPWAKPGDPHLMEDPKLKEIADRLGKXAA 852
+ A + P G DR W P +P L+E+P + +A++ G+ A
Sbjct: 188 HPYLAQNELIAHCQARGLEVTAYSP-LGSSDRAWRDPDEPVLLEEPVVLALAEKYGRSPA 246
Query: 853 Q 855
Q
Sbjct: 247 Q 247
Score = 39.9 bits (89), Expect = 0.025
Identities = 16/31 (51%), Positives = 19/31 (61%)
Frame = +2
Query: 662 QVECHPYLNXKRLKQFCEDRDIMITXYSPXG 754
QVECHPYL L C+ R + +T YSP G
Sbjct: 184 QVECHPYLAQNELIAHCQARGLEVTAYSPLG 214
>BT007003-1|AAP35649.1| 325|Homo sapiens aldo-keto reductase family
1, member A1 (aldehyde reductase) protein.
Length = 325
Score = 227 bits (555), Expect = 9e-59
Identities = 112/241 (46%), Positives = 152/241 (63%), Gaps = 1/241 (0%)
Frame = +1
Query: 136 LSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQEG 315
L G K+P+IG+GTWKS+PG+V AVK A+ +GYRHI CA +YGNE E+GEA+K + G
Sbjct: 8 LHTGQKMPLIGLGTWKSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALKEDVGPG 67
Query: 316 -VVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPT 492
V RE+LF+TSKLWNT H P+ V AL +L +L ++YLDLYL+HWP A++ D FP
Sbjct: 68 KAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDNPFPK 127
Query: 493 DADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPGH*PGRM 672
+ADG I + Y +TWKALE LV GLV++LG+SNFNS+Q+ IL ASV+P
Sbjct: 128 NADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASVRPAVLQVEC 187
Query: 673 PSVFKPXAIEAVLRRP*YYDNGVLPRWGXPDRPWAKPGDPHLMEDPKLKEIADRLGKXAA 852
+ A + P G DR W P +P L+E+P + +A++ G+ A
Sbjct: 188 HPYLAQNELIAHCQARGLEVTAYSP-LGSSDRAWRDPDEPVLLEEPVVLALAEKYGRSPA 246
Query: 853 Q 855
Q
Sbjct: 247 Q 247
Score = 39.9 bits (89), Expect = 0.025
Identities = 16/31 (51%), Positives = 19/31 (61%)
Frame = +2
Query: 662 QVECHPYLNXKRLKQFCEDRDIMITXYSPXG 754
QVECHPYL L C+ R + +T YSP G
Sbjct: 184 QVECHPYLAQNELIAHCQARGLEVTAYSPLG 214
>BC005394-1|AAH05394.1| 325|Homo sapiens aldo-keto reductase family
1, member A1 (aldehyde reductase) protein.
Length = 325
Score = 227 bits (555), Expect = 9e-59
Identities = 112/241 (46%), Positives = 152/241 (63%), Gaps = 1/241 (0%)
Frame = +1
Query: 136 LSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQEG 315
L G K+P+IG+GTWKS+PG+V AVK A+ +GYRHI CA +YGNE E+GEA+K + G
Sbjct: 8 LHTGQKMPLIGLGTWKSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALKEDVGPG 67
Query: 316 -VVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPT 492
V RE+LF+TSKLWNT H P+ V AL +L +L ++YLDLYL+HWP A++ D FP
Sbjct: 68 KAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDNPFPK 127
Query: 493 DADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPGH*PGRM 672
+ADG I + Y +TWKALE LV GLV++LG+SNFNS+Q+ IL ASV+P
Sbjct: 128 NADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASVRPAVLQVEC 187
Query: 673 PSVFKPXAIEAVLRRP*YYDNGVLPRWGXPDRPWAKPGDPHLMEDPKLKEIADRLGKXAA 852
+ A + P G DR W P +P L+E+P + +A++ G+ A
Sbjct: 188 HPYLAQNELIAHCQARGLEVTAYSP-LGSSDRAWRDPDEPVLLEEPVVLALAEKYGRSPA 246
Query: 853 Q 855
Q
Sbjct: 247 Q 247
Score = 39.9 bits (89), Expect = 0.025
Identities = 16/31 (51%), Positives = 19/31 (61%)
Frame = +2
Query: 662 QVECHPYLNXKRLKQFCEDRDIMITXYSPXG 754
QVECHPYL L C+ R + +T YSP G
Sbjct: 184 QVECHPYLAQNELIAHCQARGLEVTAYSPLG 214
>BC000670-1|AAH00670.1| 325|Homo sapiens aldo-keto reductase family
1, member A1 (aldehyde reductase) protein.
Length = 325
Score = 227 bits (555), Expect = 9e-59
Identities = 112/241 (46%), Positives = 152/241 (63%), Gaps = 1/241 (0%)
Frame = +1
Query: 136 LSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQEG 315
L G K+P+IG+GTWKS+PG+V AVK A+ +GYRHI CA +YGNE E+GEA+K + G
Sbjct: 8 LHTGQKMPLIGLGTWKSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALKEDVGPG 67
Query: 316 -VVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPT 492
V RE+LF+TSKLWNT H P+ V AL +L +L ++YLDLYL+HWP A++ D FP
Sbjct: 68 KAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDNPFPK 127
Query: 493 DADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPGH*PGRM 672
+ADG I + Y +TWKALE LV GLV++LG+SNFNS+Q+ IL ASV+P
Sbjct: 128 NADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASVRPAVLQVEC 187
Query: 673 PSVFKPXAIEAVLRRP*YYDNGVLPRWGXPDRPWAKPGDPHLMEDPKLKEIADRLGKXAA 852
+ A + P G DR W P +P L+E+P + +A++ G+ A
Sbjct: 188 HPYLAQNELIAHCQARGLEVTAYSP-LGSSDRAWRDPDEPVLLEEPVVLALAEKYGRSPA 246
Query: 853 Q 855
Q
Sbjct: 247 Q 247
Score = 39.9 bits (89), Expect = 0.025
Identities = 16/31 (51%), Positives = 19/31 (61%)
Frame = +2
Query: 662 QVECHPYLNXKRLKQFCEDRDIMITXYSPXG 754
QVECHPYL L C+ R + +T YSP G
Sbjct: 184 QVECHPYLAQNELIAHCQARGLEVTAYSPLG 214
>AL355480-3|CAI22459.1| 325|Homo sapiens aldo-keto reductase family
1, member A1 (aldehydetase, 1 protein.
Length = 325
Score = 227 bits (555), Expect = 9e-59
Identities = 112/241 (46%), Positives = 152/241 (63%), Gaps = 1/241 (0%)
Frame = +1
Query: 136 LSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQEG 315
L G K+P+IG+GTWKS+PG+V AVK A+ +GYRHI CA +YGNE E+GEA+K + G
Sbjct: 8 LHTGQKMPLIGLGTWKSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALKEDVGPG 67
Query: 316 -VVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPT 492
V RE+LF+TSKLWNT H P+ V AL +L +L ++YLDLYL+HWP A++ D FP
Sbjct: 68 KAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDNPFPK 127
Query: 493 DADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPGH*PGRM 672
+ADG I + Y +TWKALE LV GLV++LG+SNFNS+Q+ IL ASV+P
Sbjct: 128 NADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASVRPAVLQVEC 187
Query: 673 PSVFKPXAIEAVLRRP*YYDNGVLPRWGXPDRPWAKPGDPHLMEDPKLKEIADRLGKXAA 852
+ A + P G DR W P +P L+E+P + +A++ G+ A
Sbjct: 188 HPYLAQNELIAHCQARGLEVTAYSP-LGSSDRAWRDPDEPVLLEEPVVLALAEKYGRSPA 246
Query: 853 Q 855
Q
Sbjct: 247 Q 247
Score = 39.9 bits (89), Expect = 0.025
Identities = 16/31 (51%), Positives = 19/31 (61%)
Frame = +2
Query: 662 QVECHPYLNXKRLKQFCEDRDIMITXYSPXG 754
QVECHPYL L C+ R + +T YSP G
Sbjct: 184 QVECHPYLAQNELIAHCQARGLEVTAYSPLG 214
>AF112485-1|AAF01260.1| 325|Homo sapiens aldehyde reductase
protein.
Length = 325
Score = 227 bits (555), Expect = 9e-59
Identities = 112/241 (46%), Positives = 152/241 (63%), Gaps = 1/241 (0%)
Frame = +1
Query: 136 LSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQEG 315
L G K+P+IG+GTWKS+PG+V AVK A+ +GYRHI CA +YGNE E+GEA+K + G
Sbjct: 8 LHTGQKMPLIGLGTWKSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALKEDVGPG 67
Query: 316 -VVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPT 492
V RE+LF+TSKLWNT H P+ V AL +L +L ++YLDLYL+HWP A++ D FP
Sbjct: 68 KAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDNPFPK 127
Query: 493 DADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPGH*PGRM 672
+ADG I + Y +TWKALE LV GLV++LG+SNFNS+Q+ IL ASV+P
Sbjct: 128 NADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASVRPAVLQVEC 187
Query: 673 PSVFKPXAIEAVLRRP*YYDNGVLPRWGXPDRPWAKPGDPHLMEDPKLKEIADRLGKXAA 852
+ A + P G DR W P +P L+E+P + +A++ G+ A
Sbjct: 188 HPYLAQNELIAHCQARGLEVTAYSP-LGSSDRAWRDPDEPVLLEEPVVLALAEKYGRSPA 246
Query: 853 Q 855
Q
Sbjct: 247 Q 247
Score = 39.9 bits (89), Expect = 0.025
Identities = 16/31 (51%), Positives = 19/31 (61%)
Frame = +2
Query: 662 QVECHPYLNXKRLKQFCEDRDIMITXYSPXG 754
QVECHPYL L C+ R + +T YSP G
Sbjct: 184 QVECHPYLAQNELIAHCQARGLEVTAYSPLG 214
>AF036683-1|AAB92369.1| 325|Homo sapiens aldehyde reductase
protein.
Length = 325
Score = 227 bits (555), Expect = 9e-59
Identities = 112/241 (46%), Positives = 152/241 (63%), Gaps = 1/241 (0%)
Frame = +1
Query: 136 LSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQEG 315
L G K+P+IG+GTWKS+PG+V AVK A+ +GYRHI CA +YGNE E+GEA+K + G
Sbjct: 8 LHTGQKMPLIGLGTWKSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALKEDVGPG 67
Query: 316 -VVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPT 492
V RE+LF+TSKLWNT H P+ V AL +L +L ++YLDLYL+HWP A++ D FP
Sbjct: 68 KAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDNPFPK 127
Query: 493 DADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPGH*PGRM 672
+ADG I + Y +TWKALE LV GLV++LG+SNFNS+Q+ IL ASV+P
Sbjct: 128 NADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASVRPAVLQVEC 187
Query: 673 PSVFKPXAIEAVLRRP*YYDNGVLPRWGXPDRPWAKPGDPHLMEDPKLKEIADRLGKXAA 852
+ A + P G DR W P +P L+E+P + +A++ G+ A
Sbjct: 188 HPYLAQNELIAHCQARGLEVTAYSP-LGSSDRAWRDPDEPVLLEEPVVLALAEKYGRSPA 246
Query: 853 Q 855
Q
Sbjct: 247 Q 247
Score = 39.9 bits (89), Expect = 0.025
Identities = 16/31 (51%), Positives = 19/31 (61%)
Frame = +2
Query: 662 QVECHPYLNXKRLKQFCEDRDIMITXYSPXG 754
QVECHPYL L C+ R + +T YSP G
Sbjct: 184 QVECHPYLAQNELIAHCQARGLEVTAYSPLG 214
>Z28339-1|CAA82193.1| 326|Homo sapiens delta 4-3-oxosteroid 5
beta-reductase protein.
Length = 326
Score = 182 bits (444), Expect = 2e-45
Identities = 107/248 (43%), Positives = 143/248 (57%), Gaps = 8/248 (3%)
Frame = +1
Query: 136 LSNGAKIPVIGIGTW---KSKP-GEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTK 303
LS+G IP+IG+GT+ KS P G +VK AID GYRHI A++Y NE EVGEAI+ K
Sbjct: 12 LSDGNSIPIIGLGTYSEPKSTPKGACATSVKVAIDTGYRHIDGAYIYQNEHEVGEAIREK 71
Query: 304 IQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAI 483
I EG V+RED+F KLW T H P++VR LE +LR L +DY+DLY+I P A+K D I
Sbjct: 72 IAEGKVRREDIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLYIIEVPMAFKPGDEI 131
Query: 484 FPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPGH*P 663
+P D +GK + + TW+A+E GLV+SLGVSNFN +QL+ IL+ +K H P
Sbjct: 132 YPRDENGKWLYHKSNLCATWEAMEACKDAGLVKSLGVSNFNRRQLELILNKPGLK--HKP 189
Query: 664 GRMPSVFKPXAIEAVLRRP*YYDNGVLPRW---GXPDRP-WAKPGDPHLMEDPKLKEIAD 831
P + L + + V+ + G P W P L++D L +
Sbjct: 190 VSNQVECHPYFTQPKLLKFCQQHDIVITAYSPLGTSRNPIWVNVSSPPLLKDALLNSLGK 249
Query: 832 RLGKXAAQ 855
R K AAQ
Sbjct: 250 RYNKTAAQ 257
>BC130627-1|AAI30628.1| 326|Homo sapiens aldo-keto reductase family
1, member D1 (delta 4-3-ketosteroid-5-beta-reductase
protein.
Length = 326
Score = 182 bits (444), Expect = 2e-45
Identities = 107/248 (43%), Positives = 143/248 (57%), Gaps = 8/248 (3%)
Frame = +1
Query: 136 LSNGAKIPVIGIGTW---KSKP-GEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTK 303
LS+G IP+IG+GT+ KS P G +VK AID GYRHI A++Y NE EVGEAI+ K
Sbjct: 12 LSDGNSIPIIGLGTYSEPKSTPKGACATSVKVAIDTGYRHIDGAYIYQNEHEVGEAIREK 71
Query: 304 IQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAI 483
I EG V+RED+F KLW T H P++VR LE +LR L +DY+DLY+I P A+K D I
Sbjct: 72 IAEGKVRREDIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLYIIEVPMAFKPGDEI 131
Query: 484 FPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPGH*P 663
+P D +GK + + TW+A+E GLV+SLGVSNFN +QL+ IL+ +K H P
Sbjct: 132 YPRDENGKWLYHKSNLCATWEAMEACKDAGLVKSLGVSNFNRRQLELILNKPGLK--HKP 189
Query: 664 GRMPSVFKPXAIEAVLRRP*YYDNGVLPRW---GXPDRP-WAKPGDPHLMEDPKLKEIAD 831
P + L + + V+ + G P W P L++D L +
Sbjct: 190 VSNQVECHPYFTQPKLLKFCQQHDIVITAYSPLGTSRNPIWVNVSSPPLLKDALLNSLGK 249
Query: 832 RLGKXAAQ 855
R K AAQ
Sbjct: 250 RYNKTAAQ 257
>BC130625-1|AAI30626.1| 326|Homo sapiens aldo-keto reductase family
1, member D1 (delta 4-3-ketosteroid-5-beta-reductase
protein.
Length = 326
Score = 182 bits (444), Expect = 2e-45
Identities = 107/248 (43%), Positives = 143/248 (57%), Gaps = 8/248 (3%)
Frame = +1
Query: 136 LSNGAKIPVIGIGTW---KSKP-GEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTK 303
LS+G IP+IG+GT+ KS P G +VK AID GYRHI A++Y NE EVGEAI+ K
Sbjct: 12 LSDGNSIPIIGLGTYSEPKSTPKGACATSVKVAIDTGYRHIDGAYIYQNEHEVGEAIREK 71
Query: 304 IQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAI 483
I EG V+RED+F KLW T H P++VR LE +LR L +DY+DLY+I P A+K D I
Sbjct: 72 IAEGKVRREDIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLYIIEVPMAFKPGDEI 131
Query: 484 FPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPGH*P 663
+P D +GK + + TW+A+E GLV+SLGVSNFN +QL+ IL+ +K H P
Sbjct: 132 YPRDENGKWLYHKSNLCATWEAMEACKDAGLVKSLGVSNFNRRQLELILNKPGLK--HKP 189
Query: 664 GRMPSVFKPXAIEAVLRRP*YYDNGVLPRW---GXPDRP-WAKPGDPHLMEDPKLKEIAD 831
P + L + + V+ + G P W P L++D L +
Sbjct: 190 VSNQVECHPYFTQPKLLKFCQQHDIVITAYSPLGTSRNPIWVNVSSPPLLKDALLNSLGK 249
Query: 832 RLGKXAAQ 855
R K AAQ
Sbjct: 250 RYNKTAAQ 257
>AF283659-1|AAG39381.1| 326|Homo sapiens 5-beta steroid reductase
protein.
Length = 326
Score = 182 bits (444), Expect = 2e-45
Identities = 107/248 (43%), Positives = 143/248 (57%), Gaps = 8/248 (3%)
Frame = +1
Query: 136 LSNGAKIPVIGIGTW---KSKP-GEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTK 303
LS+G IP+IG+GT+ KS P G +VK AID GYRHI A++Y NE EVGEAI+ K
Sbjct: 12 LSDGNSIPIIGLGTYSEPKSTPKGACATSVKVAIDTGYRHIDGAYIYQNEHEVGEAIREK 71
Query: 304 IQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAI 483
I EG V+RED+F KLW T H P++VR LE +LR L +DY+DLY+I P A+K D I
Sbjct: 72 IAEGKVRREDIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLYIIEVPMAFKPGDEI 131
Query: 484 FPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPGH*P 663
+P D +GK + + TW+A+E GLV+SLGVSNFN +QL+ IL+ +K H P
Sbjct: 132 YPRDENGKWLYHKSNLCATWEAMEACKDAGLVKSLGVSNFNRRQLELILNKPGLK--HKP 189
Query: 664 GRMPSVFKPXAIEAVLRRP*YYDNGVLPRW---GXPDRP-WAKPGDPHLMEDPKLKEIAD 831
P + L + + V+ + G P W P L++D L +
Sbjct: 190 VSNQVECHPYFTQPKLLKFCQQHDIVITAYSPLGTSRNPIWVNVSSPPLLKDALLNSLGK 249
Query: 832 RLGKXAAQ 855
R K AAQ
Sbjct: 250 RYNKTAAQ 257
>L32592-1|AAB38486.1| 323|Homo sapiens dihydrodiol
dehydrogenase/bile acid-binding protein protein.
Length = 323
Score = 180 bits (439), Expect = 1e-44
Identities = 102/240 (42%), Positives = 138/240 (57%), Gaps = 7/240 (2%)
Frame = +1
Query: 136 LSNGAKIPVIGIGTWKSKPGEVT-----QAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKT 300
L++G +PV+G GT+ P EV +AVK AI+ GY HI A VY NE++VG AI++
Sbjct: 10 LNDGHFMPVLGFGTYA--PAEVPKSKALEAVKLAIEAGYHHIDSAHVYNNEEQVGLAIRS 67
Query: 301 KIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDA 480
KI +G VKRED+F TSKLW+ HRP+LVR ALE SL+NL +DY DLYLIH+P + K +
Sbjct: 68 KIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYADLYLIHFPVSVKPGEE 127
Query: 481 IFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVK--PG 654
+ P D +GKI F VD TW+A+E GL +S+GVSNFN + L+ IL+ +K P
Sbjct: 128 VIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNEPGLKYEPV 187
Query: 655 H*PGRMPSVFKPXAIEAVLRRP*YYDNGVLPRWGXPDRPWAKPGDPHLMEDPKLKEIADR 834
F + + + PW P P L+EDP L +A +
Sbjct: 188 CNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKK 247
Score = 50.0 bits (114), Expect = 2e-05
Identities = 19/40 (47%), Positives = 26/40 (65%)
Frame = +2
Query: 653 VTNQVECHPYLNXKRLKQFCEDRDIMITXYSPXGXLPTDP 772
V NQVECHPY N ++L FC+ +DI++ YS G +P
Sbjct: 187 VCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEP 226
>U05861-1|AAA18115.1| 323|Homo sapiens hepatic dihydrodiol
dehydrogenase protein.
Length = 323
Score = 180 bits (437), Expect = 2e-44
Identities = 101/240 (42%), Positives = 139/240 (57%), Gaps = 7/240 (2%)
Frame = +1
Query: 136 LSNGAKIPVIGIGTWKSKPGEVT-----QAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKT 300
L++G +PV+G GT+ P EV +A K AI+ G+RHI A +Y NE++VG AI++
Sbjct: 10 LNDGHFMPVLGFGTYA--PAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRS 67
Query: 301 KIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDA 480
KI +G VKRED+F TSKLW HRP+LVR ALE SL+NL +DY+DLYLIH+P + K +
Sbjct: 68 KIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEE 127
Query: 481 IFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASV--KPG 654
+ P D +GKI F VD TW+A+E GL +S+GVSNFN +QL+ IL+ + KP
Sbjct: 128 VIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPV 187
Query: 655 H*PGRMPSVFKPXAIEAVLRRP*YYDNGVLPRWGXPDRPWAKPGDPHLMEDPKLKEIADR 834
F + + + PW P P L+EDP L +A +
Sbjct: 188 CNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKK 247
Score = 50.0 bits (114), Expect = 2e-05
Identities = 19/40 (47%), Positives = 26/40 (65%)
Frame = +2
Query: 653 VTNQVECHPYLNXKRLKQFCEDRDIMITXYSPXGXLPTDP 772
V NQVECHPY N ++L FC+ +DI++ YS G +P
Sbjct: 187 VCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEP 226
>U05684-1|AAA16227.1| 323|Homo sapiens dihydrodiol dehydrogenase
protein.
Length = 323
Score = 180 bits (437), Expect = 2e-44
Identities = 101/240 (42%), Positives = 139/240 (57%), Gaps = 7/240 (2%)
Frame = +1
Query: 136 LSNGAKIPVIGIGTWKSKPGEVT-----QAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKT 300
L++G +PV+G GT+ P EV +A K AI+ G+RHI A +Y NE++VG AI++
Sbjct: 10 LNDGHFMPVLGFGTYA--PAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRS 67
Query: 301 KIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDA 480
KI +G VKRED+F TSKLW HRP+LVR ALE SL+NL +DY+DLYLIH+P + K +
Sbjct: 68 KIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEE 127
Query: 481 IFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASV--KPG 654
+ P D +GKI F VD TW+A+E GL +S+GVSNFN +QL+ IL+ + KP
Sbjct: 128 VIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPV 187
Query: 655 H*PGRMPSVFKPXAIEAVLRRP*YYDNGVLPRWGXPDRPWAKPGDPHLMEDPKLKEIADR 834
F + + + PW P P L+EDP L +A +
Sbjct: 188 CNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKK 247
Score = 50.0 bits (114), Expect = 2e-05
Identities = 19/40 (47%), Positives = 26/40 (65%)
Frame = +2
Query: 653 VTNQVECHPYLNXKRLKQFCEDRDIMITXYSPXGXLPTDP 772
V NQVECHPY N ++L FC+ +DI++ YS G +P
Sbjct: 187 VCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEP 226
>U05598-1|AAA20937.1| 323|Homo sapiens dihydrodiol dehydrogenase
protein.
Length = 323
Score = 180 bits (437), Expect = 2e-44
Identities = 101/240 (42%), Positives = 139/240 (57%), Gaps = 7/240 (2%)
Frame = +1
Query: 136 LSNGAKIPVIGIGTWKSKPGEVT-----QAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKT 300
L++G +PV+G GT+ P EV +AVK AI+ G+ HI A VY NE++VG AI++
Sbjct: 10 LNDGHFMPVLGFGTYA--PAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLAIRS 67
Query: 301 KIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDA 480
KI +G VKRED+F TSKLW+ HRP+LVR ALE SL+NL +DY+DLYLIH+P + K +
Sbjct: 68 KIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEE 127
Query: 481 IFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASV--KPG 654
+ P D +GKI F VD TW+A+E GL +S+GVSNFN + L+ IL+ + KP
Sbjct: 128 VIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKYKPV 187
Query: 655 H*PGRMPSVFKPXAIEAVLRRP*YYDNGVLPRWGXPDRPWAKPGDPHLMEDPKLKEIADR 834
F + + + PW P P L+EDP L +A +
Sbjct: 188 CNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKK 247
Score = 50.0 bits (114), Expect = 2e-05
Identities = 19/40 (47%), Positives = 26/40 (65%)
Frame = +2
Query: 653 VTNQVECHPYLNXKRLKQFCEDRDIMITXYSPXGXLPTDP 772
V NQVECHPY N ++L FC+ +DI++ YS G +P
Sbjct: 187 VCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEP 226
>S68330-1|AAD14013.1| 323|Homo sapiens chlordecone reductase
homolog protein.
Length = 323
Score = 180 bits (437), Expect = 2e-44
Identities = 101/240 (42%), Positives = 139/240 (57%), Gaps = 7/240 (2%)
Frame = +1
Query: 136 LSNGAKIPVIGIGTWKSKPGEVT-----QAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKT 300
L++G +PV+G GT+ P EV +AVK AI+ G+ HI A VY NE++VG AI++
Sbjct: 10 LNDGHFMPVLGFGTYA--PAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLAIRS 67
Query: 301 KIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDA 480
KI +G VKRED+F TSKLW+ HRP+LVR ALE SL+NL +DY+DLYLIH+P + K +
Sbjct: 68 KIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEE 127
Query: 481 IFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVK--PG 654
+ P D +GKI F VD TW+A+E GL +S+GVSNFN + L+ IL+ +K P
Sbjct: 128 VIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNEPGLKYEPV 187
Query: 655 H*PGRMPSVFKPXAIEAVLRRP*YYDNGVLPRWGXPDRPWAKPGDPHLMEDPKLKEIADR 834
F + + + PW P P L+EDP L +A +
Sbjct: 188 CNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKK 247
Score = 50.0 bits (114), Expect = 2e-05
Identities = 19/40 (47%), Positives = 26/40 (65%)
Frame = +2
Query: 653 VTNQVECHPYLNXKRLKQFCEDRDIMITXYSPXGXLPTDP 772
V NQVECHPY N ++L FC+ +DI++ YS G +P
Sbjct: 187 VCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEP 226
>M86609-1|AAB02880.1| 323|Homo sapiens dihydrodiol dehydrogenase
protein.
Length = 323
Score = 180 bits (437), Expect = 2e-44
Identities = 101/240 (42%), Positives = 139/240 (57%), Gaps = 7/240 (2%)
Frame = +1
Query: 136 LSNGAKIPVIGIGTWKSKPGEVT-----QAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKT 300
L++G +PV+G GT+ P EV +A K AI+ G+RHI A +Y NE++VG AI++
Sbjct: 10 LNDGHFMPVLGFGTYA--PAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRS 67
Query: 301 KIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDA 480
KI +G VKRED+F TSKLW HRP+LVR ALE SL+NL +DY+DLYLIH+P + K +
Sbjct: 68 KIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEE 127
Query: 481 IFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASV--KPG 654
+ P D +GKI F VD TW+A+E GL +S+GVSNFN +QL+ IL+ + KP
Sbjct: 128 VIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPV 187
Query: 655 H*PGRMPSVFKPXAIEAVLRRP*YYDNGVLPRWGXPDRPWAKPGDPHLMEDPKLKEIADR 834
F + + + PW P P L+EDP L +A +
Sbjct: 188 CNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKK 247
Score = 50.0 bits (114), Expect = 2e-05
Identities = 19/40 (47%), Positives = 26/40 (65%)
Frame = +2
Query: 653 VTNQVECHPYLNXKRLKQFCEDRDIMITXYSPXGXLPTDP 772
V NQVECHPY N ++L FC+ +DI++ YS G +P
Sbjct: 187 VCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEP 226
>BT007197-1|AAP35861.1| 323|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 323
Score = 180 bits (437), Expect = 2e-44
Identities = 101/240 (42%), Positives = 139/240 (57%), Gaps = 7/240 (2%)
Frame = +1
Query: 136 LSNGAKIPVIGIGTWKSKPGEVT-----QAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKT 300
L++G +PV+G GT+ P EV +A K AI+ G+RHI A +Y NE++VG AI++
Sbjct: 10 LNDGHFMPVLGFGTYA--PAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRS 67
Query: 301 KIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDA 480
KI +G VKRED+F TSKLW HRP+LVR ALE SL+NL +DY+DLYLIH+P + K +
Sbjct: 68 KIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEE 127
Query: 481 IFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASV--KPG 654
+ P D +GKI F VD TW+A+E GL +S+GVSNFN +QL+ IL+ + KP
Sbjct: 128 VIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPV 187
Query: 655 H*PGRMPSVFKPXAIEAVLRRP*YYDNGVLPRWGXPDRPWAKPGDPHLMEDPKLKEIADR 834
F + + + PW P P L+EDP L +A +
Sbjct: 188 CNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKK 247
Score = 50.0 bits (114), Expect = 2e-05
Identities = 19/40 (47%), Positives = 26/40 (65%)
Frame = +2
Query: 653 VTNQVECHPYLNXKRLKQFCEDRDIMITXYSPXGXLPTDP 772
V NQVECHPY N ++L FC+ +DI++ YS G +P
Sbjct: 187 VCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEP 226
>BT006653-1|AAP35299.1| 323|Homo sapiens aldo-keto reductase family
1, member C2 (dihydrodiol dehydrogenase 2; bile acid
protein.
Length = 323
Score = 180 bits (437), Expect = 2e-44
Identities = 101/240 (42%), Positives = 139/240 (57%), Gaps = 7/240 (2%)
Frame = +1
Query: 136 LSNGAKIPVIGIGTWKSKPGEVT-----QAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKT 300
L++G +PV+G GT+ P EV +AVK AI+ G+ HI A VY NE++VG AI++
Sbjct: 10 LNDGHFMPVLGFGTYA--PAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLAIRS 67
Query: 301 KIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDA 480
KI +G VKRED+F TSKLW+ HRP+LVR ALE SL+NL +DY+DLYLIH+P + K +
Sbjct: 68 KIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEE 127
Query: 481 IFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASV--KPG 654
+ P D +GKI F VD TW+A+E GL +S+GVSNFN + L+ IL+ + KP
Sbjct: 128 VIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKYKPV 187
Query: 655 H*PGRMPSVFKPXAIEAVLRRP*YYDNGVLPRWGXPDRPWAKPGDPHLMEDPKLKEIADR 834
F + + + PW P P L+EDP L +A +
Sbjct: 188 CNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKK 247
Score = 50.0 bits (114), Expect = 2e-05
Identities = 19/40 (47%), Positives = 26/40 (65%)
Frame = +2
Query: 653 VTNQVECHPYLNXKRLKQFCEDRDIMITXYSPXGXLPTDP 772
V NQVECHPY N ++L FC+ +DI++ YS G +P
Sbjct: 187 VCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEP 226
>BC063574-1|AAH63574.1| 323|Homo sapiens aldo-keto reductase family
1, member C2 (dihydrodiol dehydrogenase 2; bile acid
protein.
Length = 323
Score = 180 bits (437), Expect = 2e-44
Identities = 101/240 (42%), Positives = 139/240 (57%), Gaps = 7/240 (2%)
Frame = +1
Query: 136 LSNGAKIPVIGIGTWKSKPGEVT-----QAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKT 300
L++G +PV+G GT+ P EV +AVK AI+ G+ HI A VY NE++VG AI++
Sbjct: 10 LNDGHFMPVLGFGTYA--PAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLAIRS 67
Query: 301 KIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDA 480
KI +G VKRED+F TSKLW+ HRP+LVR ALE SL+NL +DY+DLYLIH+P + K +
Sbjct: 68 KIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEE 127
Query: 481 IFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASV--KPG 654
+ P D +GKI F VD TW+A+E GL +S+GVSNFN + L+ IL+ + KP
Sbjct: 128 VIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKYKPV 187
Query: 655 H*PGRMPSVFKPXAIEAVLRRP*YYDNGVLPRWGXPDRPWAKPGDPHLMEDPKLKEIADR 834
F + + + PW P P L+EDP L +A +
Sbjct: 188 CNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKK 247
Score = 50.0 bits (114), Expect = 2e-05
Identities = 19/40 (47%), Positives = 26/40 (65%)
Frame = +2
Query: 653 VTNQVECHPYLNXKRLKQFCEDRDIMITXYSPXGXLPTDP 772
V NQVECHPY N ++L FC+ +DI++ YS G +P
Sbjct: 187 VCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEP 226
>BC040210-1|AAH40210.1| 323|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 323
Score = 180 bits (437), Expect = 2e-44
Identities = 101/240 (42%), Positives = 139/240 (57%), Gaps = 7/240 (2%)
Frame = +1
Query: 136 LSNGAKIPVIGIGTWKSKPGEVT-----QAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKT 300
L++G +PV+G GT+ P EV +A K AI+ G+RHI A +Y NE++VG AI++
Sbjct: 10 LNDGHFMPVLGFGTYA--PAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRS 67
Query: 301 KIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDA 480
KI +G VKRED+F TSKLW HRP+LVR ALE SL+NL +DY+DLYLIH+P + K +
Sbjct: 68 KIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEE 127
Query: 481 IFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASV--KPG 654
+ P D +GKI F VD TW+A+E GL +S+GVSNFN +QL+ IL+ + KP
Sbjct: 128 VIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPV 187
Query: 655 H*PGRMPSVFKPXAIEAVLRRP*YYDNGVLPRWGXPDRPWAKPGDPHLMEDPKLKEIADR 834
F + + + PW P P L+EDP L +A +
Sbjct: 188 CNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKK 247
Score = 50.0 bits (114), Expect = 2e-05
Identities = 19/40 (47%), Positives = 26/40 (65%)
Frame = +2
Query: 653 VTNQVECHPYLNXKRLKQFCEDRDIMITXYSPXGXLPTDP 772
V NQVECHPY N ++L FC+ +DI++ YS G +P
Sbjct: 187 VCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEP 226
>BC020216-1|AAH20216.1| 323|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 323
Score = 180 bits (437), Expect = 2e-44
Identities = 101/240 (42%), Positives = 139/240 (57%), Gaps = 7/240 (2%)
Frame = +1
Query: 136 LSNGAKIPVIGIGTWKSKPGEVT-----QAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKT 300
L++G +PV+G GT+ P EV +A K AI+ G+RHI A +Y NE++VG AI++
Sbjct: 10 LNDGHFMPVLGFGTYA--PAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRS 67
Query: 301 KIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDA 480
KI +G VKRED+F TSKLW HRP+LVR ALE SL+NL +DY+DLYLIH+P + K +
Sbjct: 68 KIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEE 127
Query: 481 IFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASV--KPG 654
+ P D +GKI F VD TW+A+E GL +S+GVSNFN +QL+ IL+ + KP
Sbjct: 128 VIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPV 187
Query: 655 H*PGRMPSVFKPXAIEAVLRRP*YYDNGVLPRWGXPDRPWAKPGDPHLMEDPKLKEIADR 834
F + + + PW P P L+EDP L +A +
Sbjct: 188 CNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKK 247
Score = 50.0 bits (114), Expect = 2e-05
Identities = 19/40 (47%), Positives = 26/40 (65%)
Frame = +2
Query: 653 VTNQVECHPYLNXKRLKQFCEDRDIMITXYSPXGXLPTDP 772
V NQVECHPY N ++L FC+ +DI++ YS G +P
Sbjct: 187 VCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEP 226
>BC015490-1|AAH15490.1| 323|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 323
Score = 180 bits (437), Expect = 2e-44
Identities = 101/240 (42%), Positives = 139/240 (57%), Gaps = 7/240 (2%)
Frame = +1
Query: 136 LSNGAKIPVIGIGTWKSKPGEVT-----QAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKT 300
L++G +PV+G GT+ P EV +A K AI+ G+RHI A +Y NE++VG AI++
Sbjct: 10 LNDGHFMPVLGFGTYA--PAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRS 67
Query: 301 KIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDA 480
KI +G VKRED+F TSKLW HRP+LVR ALE SL+NL +DY+DLYLIH+P + K +
Sbjct: 68 KIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEE 127
Query: 481 IFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASV--KPG 654
+ P D +GKI F VD TW+A+E GL +S+GVSNFN +QL+ IL+ + KP
Sbjct: 128 VIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPV 187
Query: 655 H*PGRMPSVFKPXAIEAVLRRP*YYDNGVLPRWGXPDRPWAKPGDPHLMEDPKLKEIADR 834
F + + + PW P P L+EDP L +A +
Sbjct: 188 CNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKK 247
Score = 50.0 bits (114), Expect = 2e-05
Identities = 19/40 (47%), Positives = 26/40 (65%)
Frame = +2
Query: 653 VTNQVECHPYLNXKRLKQFCEDRDIMITXYSPXGXLPTDP 772
V NQVECHPY N ++L FC+ +DI++ YS G +P
Sbjct: 187 VCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEP 226
>BC007024-1|AAH07024.1| 323|Homo sapiens aldo-keto reductase family
1, member C2 (dihydrodiol dehydrogenase 2; bile acid
protein.
Length = 323
Score = 180 bits (437), Expect = 2e-44
Identities = 101/240 (42%), Positives = 139/240 (57%), Gaps = 7/240 (2%)
Frame = +1
Query: 136 LSNGAKIPVIGIGTWKSKPGEVT-----QAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKT 300
L++G +PV+G GT+ P EV +AVK AI+ G+ HI A VY NE++VG AI++
Sbjct: 10 LNDGHFMPVLGFGTYA--PAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLAIRS 67
Query: 301 KIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDA 480
KI +G VKRED+F TSKLW+ HRP+LVR ALE SL+NL +DY+DLYLIH+P + K +
Sbjct: 68 KIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEE 127
Query: 481 IFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASV--KPG 654
+ P D +GKI F VD TW+A+E GL +S+GVSNFN + L+ IL+ + KP
Sbjct: 128 VIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKYKPV 187
Query: 655 H*PGRMPSVFKPXAIEAVLRRP*YYDNGVLPRWGXPDRPWAKPGDPHLMEDPKLKEIADR 834
F + + + PW P P L+EDP L +A +
Sbjct: 188 CNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKK 247
Score = 50.0 bits (114), Expect = 2e-05
Identities = 19/40 (47%), Positives = 26/40 (65%)
Frame = +2
Query: 653 VTNQVECHPYLNXKRLKQFCEDRDIMITXYSPXGXLPTDP 772
V NQVECHPY N ++L FC+ +DI++ YS G +P
Sbjct: 187 VCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEP 226
>BC002862-1|AAH02862.1| 307|Homo sapiens AKR1CL2 protein protein.
Length = 307
Score = 180 bits (437), Expect = 2e-44
Identities = 87/184 (47%), Positives = 120/184 (65%), Gaps = 19/184 (10%)
Frame = +1
Query: 154 IPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQEGVVKRED 333
IP +G+ +WK+ PG+VT+AVK+AID GYRH CA+ Y NE+EVG I+ KI+EG V+RED
Sbjct: 4 IPAVGLSSWKASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEGAVRRED 63
Query: 334 LFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKE---------DDAIF 486
LFI +KLW T H+ LV A SL+ L ++YLDLYLIHWP +K + F
Sbjct: 64 LFIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPMGFKPPHPEWIMSCSELSF 123
Query: 487 ----------PTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDN 636
P D + SD D++DTW+A+E LV GLV+++GVSNFN +QL+R+L+
Sbjct: 124 CLSHPRVQDLPLDESNMVIPSDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERLLNK 183
Query: 637 ASVK 648
++
Sbjct: 184 PGLR 187
Score = 52.8 bits (121), Expect = 3e-06
Identities = 19/34 (55%), Positives = 24/34 (70%)
Frame = +2
Query: 653 VTNQVECHPYLNXKRLKQFCEDRDIMITXYSPXG 754
+TNQ+ECHPYL K L FC+ RD+ +T Y P G
Sbjct: 191 LTNQIECHPYLTQKNLISFCQSRDVSVTAYRPLG 224
>AL713867-2|CAI16409.1| 323|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 323
Score = 180 bits (437), Expect = 2e-44
Identities = 101/240 (42%), Positives = 139/240 (57%), Gaps = 7/240 (2%)
Frame = +1
Query: 136 LSNGAKIPVIGIGTWKSKPGEVT-----QAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKT 300
L++G +PV+G GT+ P EV +A K AI+ G+RHI A +Y NE++VG AI++
Sbjct: 10 LNDGHFMPVLGFGTYA--PAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRS 67
Query: 301 KIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDA 480
KI +G VKRED+F TSKLW HRP+LVR ALE SL+NL +DY+DLYLIH+P + K +
Sbjct: 68 KIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEE 127
Query: 481 IFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASV--KPG 654
+ P D +GKI F VD TW+A+E GL +S+GVSNFN +QL+ IL+ + KP
Sbjct: 128 VIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPV 187
Query: 655 H*PGRMPSVFKPXAIEAVLRRP*YYDNGVLPRWGXPDRPWAKPGDPHLMEDPKLKEIADR 834
F + + + PW P P L+EDP L +A +
Sbjct: 188 CNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKK 247
Score = 50.0 bits (114), Expect = 2e-05
Identities = 19/40 (47%), Positives = 26/40 (65%)
Frame = +2
Query: 653 VTNQVECHPYLNXKRLKQFCEDRDIMITXYSPXGXLPTDP 772
V NQVECHPY N ++L FC+ +DI++ YS G +P
Sbjct: 187 VCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEP 226
>AL713867-1|CAI16408.1| 323|Homo sapiens aldo-keto reductase family
1, member C2 (dihydrodiol dehydrogenase 2; bile acid
protein.
Length = 323
Score = 180 bits (437), Expect = 2e-44
Identities = 101/240 (42%), Positives = 139/240 (57%), Gaps = 7/240 (2%)
Frame = +1
Query: 136 LSNGAKIPVIGIGTWKSKPGEVT-----QAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKT 300
L++G +PV+G GT+ P EV +AVK AI+ G+ HI A VY NE++VG AI++
Sbjct: 10 LNDGHFMPVLGFGTYA--PAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLAIRS 67
Query: 301 KIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDA 480
KI +G VKRED+F TSKLW+ HRP+LVR ALE SL+NL +DY+DLYLIH+P + K +
Sbjct: 68 KIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEE 127
Query: 481 IFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASV--KPG 654
+ P D +GKI F VD TW+A+E GL +S+GVSNFN + L+ IL+ + KP
Sbjct: 128 VIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKYKPV 187
Query: 655 H*PGRMPSVFKPXAIEAVLRRP*YYDNGVLPRWGXPDRPWAKPGDPHLMEDPKLKEIADR 834
F + + + PW P P L+EDP L +A +
Sbjct: 188 CNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKK 247
Score = 50.0 bits (114), Expect = 2e-05
Identities = 19/40 (47%), Positives = 26/40 (65%)
Frame = +2
Query: 653 VTNQVECHPYLNXKRLKQFCEDRDIMITXYSPXGXLPTDP 772
V NQVECHPY N ++L FC+ +DI++ YS G +P
Sbjct: 187 VCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEP 226
>AL391427-1|CAI14726.1| 323|Homo sapiens aldo-keto reductase family
1, member C2 (dihydrodiol dehydrogenase 2; bile acid
protein.
Length = 323
Score = 180 bits (437), Expect = 2e-44
Identities = 101/240 (42%), Positives = 139/240 (57%), Gaps = 7/240 (2%)
Frame = +1
Query: 136 LSNGAKIPVIGIGTWKSKPGEVT-----QAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKT 300
L++G +PV+G GT+ P EV +AVK AI+ G+ HI A VY NE++VG AI++
Sbjct: 10 LNDGHFMPVLGFGTYA--PAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLAIRS 67
Query: 301 KIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDA 480
KI +G VKRED+F TSKLW+ HRP+LVR ALE SL+NL +DY+DLYLIH+P + K +
Sbjct: 68 KIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEE 127
Query: 481 IFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASV--KPG 654
+ P D +GKI F VD TW+A+E GL +S+GVSNFN + L+ IL+ + KP
Sbjct: 128 VIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKYKPV 187
Query: 655 H*PGRMPSVFKPXAIEAVLRRP*YYDNGVLPRWGXPDRPWAKPGDPHLMEDPKLKEIADR 834
F + + + PW P P L+EDP L +A +
Sbjct: 188 CNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKK 247
Score = 50.0 bits (114), Expect = 2e-05
Identities = 19/40 (47%), Positives = 26/40 (65%)
Frame = +2
Query: 653 VTNQVECHPYLNXKRLKQFCEDRDIMITXYSPXGXLPTDP 772
V NQVECHPY N ++L FC+ +DI++ YS G +P
Sbjct: 187 VCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEP 226
>AF263242-1|AAK58523.1| 320|Homo sapiens aldo-keto reductase
loopADR protein.
Length = 320
Score = 180 bits (437), Expect = 2e-44
Identities = 87/184 (47%), Positives = 120/184 (65%), Gaps = 19/184 (10%)
Frame = +1
Query: 154 IPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQEGVVKRED 333
IP +G+ +WK+ PG+VT+AVK+AID GYRH CA+ Y NE+EVG I+ KI+EG V+RED
Sbjct: 4 IPAVGLSSWKASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEGAVRRED 63
Query: 334 LFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKE---------DDAIF 486
LFI +KLW T H+ LV A SL+ L ++YLDLYLIHWP +K + F
Sbjct: 64 LFIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPMGFKPPHPEWIMSCSELSF 123
Query: 487 ----------PTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDN 636
P D + SD D++DTW+A+E LV GLV+++GVSNFN +QL+R+L+
Sbjct: 124 CLSHPRVQDLPLDESNMVIPSDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERLLNK 183
Query: 637 ASVK 648
++
Sbjct: 184 PGLR 187
Score = 52.8 bits (121), Expect = 3e-06
Identities = 19/34 (55%), Positives = 24/34 (70%)
Frame = +2
Query: 653 VTNQVECHPYLNXKRLKQFCEDRDIMITXYSPXG 754
+TNQ+ECHPYL K L FC+ RD+ +T Y P G
Sbjct: 191 LTNQIECHPYLTQKNLISFCQSRDVSVTAYRPLG 224
>AB209017-1|BAD92254.1| 286|Homo sapiens aldo-keto reductase family
1, member C2 variant protein.
Length = 286
Score = 180 bits (437), Expect = 2e-44
Identities = 101/240 (42%), Positives = 139/240 (57%), Gaps = 7/240 (2%)
Frame = +1
Query: 136 LSNGAKIPVIGIGTWKSKPGEVT-----QAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKT 300
L++G +PV+G GT+ P EV +AVK AI+ G+ HI A VY NE++VG AI++
Sbjct: 23 LNDGHFMPVLGFGTYA--PAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLAIRS 80
Query: 301 KIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDA 480
KI +G VKRED+F TSKLW+ HRP+LVR ALE SL+NL +DY+DLYLIH+P + K +
Sbjct: 81 KIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEE 140
Query: 481 IFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASV--KPG 654
+ P D +GKI F VD TW+A+E GL +S+GVSNFN + L+ IL+ + KP
Sbjct: 141 VIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKYKPV 200
Query: 655 H*PGRMPSVFKPXAIEAVLRRP*YYDNGVLPRWGXPDRPWAKPGDPHLMEDPKLKEIADR 834
F + + + PW P P L+EDP L +A +
Sbjct: 201 CNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKK 260
Score = 50.0 bits (114), Expect = 2e-05
Identities = 19/40 (47%), Positives = 26/40 (65%)
Frame = +2
Query: 653 VTNQVECHPYLNXKRLKQFCEDRDIMITXYSPXGXLPTDP 772
V NQVECHPY N ++L FC+ +DI++ YS G +P
Sbjct: 200 VCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEP 239
>AB055603-1|BAC54568.1| 307|Homo sapiens aldo-keto reductase
related protein 4 protein.
Length = 307
Score = 180 bits (437), Expect = 2e-44
Identities = 87/184 (47%), Positives = 120/184 (65%), Gaps = 19/184 (10%)
Frame = +1
Query: 154 IPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQEGVVKRED 333
IP +G+ +WK+ PG+VT+AVK+AID GYRH CA+ Y NE+EVG I+ KI+EG V+RED
Sbjct: 4 IPAVGLSSWKASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEGAVRRED 63
Query: 334 LFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKE---------DDAIF 486
LFI +KLW T H+ LV A SL+ L ++YLDLYLIHWP +K + F
Sbjct: 64 LFIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPMGFKPPHPEWIMSCSELSF 123
Query: 487 ----------PTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDN 636
P D + SD D++DTW+A+E LV GLV+++GVSNFN +QL+R+L+
Sbjct: 124 CLSHPRVQDLPLDESNMVIPSDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERLLNK 183
Query: 637 ASVK 648
++
Sbjct: 184 PGLR 187
Score = 52.8 bits (121), Expect = 3e-06
Identities = 19/34 (55%), Positives = 24/34 (70%)
Frame = +2
Query: 653 VTNQVECHPYLNXKRLKQFCEDRDIMITXYSPXG 754
+TNQ+ECHPYL K L FC+ RD+ +T Y P G
Sbjct: 191 LTNQIECHPYLTQKNLISFCQSRDVSVTAYRPLG 224
>AB040821-1|BAC54566.1| 263|Homo sapiens aldo-keto reductase
related protein 2 protein.
Length = 263
Score = 180 bits (437), Expect = 2e-44
Identities = 87/184 (47%), Positives = 120/184 (65%), Gaps = 19/184 (10%)
Frame = +1
Query: 154 IPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQEGVVKRED 333
IP +G+ +WK+ PG+VT+AVK+AID GYRH CA+ Y NE+EVG I+ KI+EG V+RED
Sbjct: 4 IPAVGLSSWKASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEGAVRRED 63
Query: 334 LFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKE---------DDAIF 486
LFI +KLW T H+ LV A SL+ L ++YLDLYLIHWP +K + F
Sbjct: 64 LFIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPMGFKPPHPEWIMSCSELSF 123
Query: 487 ----------PTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDN 636
P D + SD D++DTW+A+E LV GLV+++GVSNFN +QL+R+L+
Sbjct: 124 CLSHPRVQDLPLDESNMVIPSDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERLLNK 183
Query: 637 ASVK 648
++
Sbjct: 184 PGLR 187
>AB040820-1|BAC54565.1| 250|Homo sapiens aldo-keto reductase
related protein 1 protein.
Length = 250
Score = 180 bits (437), Expect = 2e-44
Identities = 87/184 (47%), Positives = 120/184 (65%), Gaps = 19/184 (10%)
Frame = +1
Query: 154 IPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQEGVVKRED 333
IP +G+ +WK+ PG+VT+AVK+AID GYRH CA+ Y NE+EVG I+ KI+EG V+RED
Sbjct: 4 IPAVGLSSWKASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEGAVRRED 63
Query: 334 LFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKE---------DDAIF 486
LFI +KLW T H+ LV A SL+ L ++YLDLYLIHWP +K + F
Sbjct: 64 LFIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPMGFKPPHPEWIMSCSELSF 123
Query: 487 ----------PTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDN 636
P D + SD D++DTW+A+E LV GLV+++GVSNFN +QL+R+L+
Sbjct: 124 CLSHPRVQDLPLDESNMVIPSDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERLLNK 183
Query: 637 ASVK 648
++
Sbjct: 184 PGLR 187
>AB032153-1|BAA92891.1| 323|Homo sapiens bile acid-binding protein
protein.
Length = 323
Score = 180 bits (437), Expect = 2e-44
Identities = 101/240 (42%), Positives = 139/240 (57%), Gaps = 7/240 (2%)
Frame = +1
Query: 136 LSNGAKIPVIGIGTWKSKPGEVT-----QAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKT 300
L++G +PV+G GT+ P EV +AVK AI+ G+ HI A VY NE++VG AI++
Sbjct: 10 LNDGHFMPVLGFGTYA--PAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLAIRS 67
Query: 301 KIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDA 480
KI +G VKRED+F TSKLW+ HRP+LVR ALE SL+NL +DY+DLYLIH+P + K +
Sbjct: 68 KIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEE 127
Query: 481 IFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASV--KPG 654
+ P D +GKI F VD TW+A+E GL +S+GVSNFN + L+ IL+ + KP
Sbjct: 128 VIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKYKPV 187
Query: 655 H*PGRMPSVFKPXAIEAVLRRP*YYDNGVLPRWGXPDRPWAKPGDPHLMEDPKLKEIADR 834
F + + + PW P P L+EDP L +A +
Sbjct: 188 CNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKK 247
Score = 50.0 bits (114), Expect = 2e-05
Identities = 19/40 (47%), Positives = 26/40 (65%)
Frame = +2
Query: 653 VTNQVECHPYLNXKRLKQFCEDRDIMITXYSPXGXLPTDP 772
V NQVECHPY N ++L FC+ +DI++ YS G +P
Sbjct: 187 VCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEP 226
>AB032150-1|BAA92886.1| 323|Homo sapiens 20 alph-hydroxysteroid
dehydrogenase protein.
Length = 323
Score = 180 bits (437), Expect = 2e-44
Identities = 101/240 (42%), Positives = 139/240 (57%), Gaps = 7/240 (2%)
Frame = +1
Query: 136 LSNGAKIPVIGIGTWKSKPGEVT-----QAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKT 300
L++G +PV+G GT+ P EV +A K AI+ G+RHI A +Y NE++VG AI++
Sbjct: 10 LNDGHFMPVLGFGTYA--PAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRS 67
Query: 301 KIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDA 480
KI +G VKRED+F TSKLW HRP+LVR ALE SL+NL +DY+DLYLIH+P + K +
Sbjct: 68 KIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEE 127
Query: 481 IFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASV--KPG 654
+ P D +GKI F VD TW+A+E GL +S+GVSNFN +QL+ IL+ + KP
Sbjct: 128 VIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPV 187
Query: 655 H*PGRMPSVFKPXAIEAVLRRP*YYDNGVLPRWGXPDRPWAKPGDPHLMEDPKLKEIADR 834
F + + + PW P P L+EDP L +A +
Sbjct: 188 CNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKK 247
Score = 50.0 bits (114), Expect = 2e-05
Identities = 19/40 (47%), Positives = 26/40 (65%)
Frame = +2
Query: 653 VTNQVECHPYLNXKRLKQFCEDRDIMITXYSPXGXLPTDP 772
V NQVECHPY N ++L FC+ +DI++ YS G +P
Sbjct: 187 VCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEP 226
>AB031084-1|BAA92884.1| 323|Homo sapiens bile acid-binding protein
protein.
Length = 323
Score = 180 bits (437), Expect = 2e-44
Identities = 101/240 (42%), Positives = 139/240 (57%), Gaps = 7/240 (2%)
Frame = +1
Query: 136 LSNGAKIPVIGIGTWKSKPGEVT-----QAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKT 300
L++G +PV+G GT+ P EV +AVK AI+ G+ HI A VY NE++VG AI++
Sbjct: 10 LNDGHFMPVLGFGTYA--PAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLAIRS 67
Query: 301 KIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDA 480
KI +G VKRED+F TSKLW+ HRP+LVR ALE SL+NL +DY+DLYLIH+P + K +
Sbjct: 68 KIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEE 127
Query: 481 IFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASV--KPG 654
+ P D +GKI F VD TW+A+E GL +S+GVSNFN + L+ IL+ + KP
Sbjct: 128 VIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKYKPV 187
Query: 655 H*PGRMPSVFKPXAIEAVLRRP*YYDNGVLPRWGXPDRPWAKPGDPHLMEDPKLKEIADR 834
F + + + PW P P L+EDP L +A +
Sbjct: 188 CNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKK 247
Score = 50.0 bits (114), Expect = 2e-05
Identities = 19/40 (47%), Positives = 26/40 (65%)
Frame = +2
Query: 653 VTNQVECHPYLNXKRLKQFCEDRDIMITXYSPXGXLPTDP 772
V NQVECHPY N ++L FC+ +DI++ YS G +P
Sbjct: 187 VCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEP 226
>AB031083-1|BAA92883.1| 323|Homo sapiens 20 alpha-hydroxysteroid
dehydrogenase protein.
Length = 323
Score = 180 bits (437), Expect = 2e-44
Identities = 101/240 (42%), Positives = 139/240 (57%), Gaps = 7/240 (2%)
Frame = +1
Query: 136 LSNGAKIPVIGIGTWKSKPGEVT-----QAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKT 300
L++G +PV+G GT+ P EV +A K AI+ G+RHI A +Y NE++VG AI++
Sbjct: 10 LNDGHFMPVLGFGTYA--PAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRS 67
Query: 301 KIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDA 480
KI +G VKRED+F TSKLW HRP+LVR ALE SL+NL +DY+DLYLIH+P + K +
Sbjct: 68 KIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEE 127
Query: 481 IFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASV--KPG 654
+ P D +GKI F VD TW+A+E GL +S+GVSNFN +QL+ IL+ + KP
Sbjct: 128 VIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPV 187
Query: 655 H*PGRMPSVFKPXAIEAVLRRP*YYDNGVLPRWGXPDRPWAKPGDPHLMEDPKLKEIADR 834
F + + + PW P P L+EDP L +A +
Sbjct: 188 CNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKK 247
Score = 50.0 bits (114), Expect = 2e-05
Identities = 19/40 (47%), Positives = 26/40 (65%)
Frame = +2
Query: 653 VTNQVECHPYLNXKRLKQFCEDRDIMITXYSPXGXLPTDP 772
V NQVECHPY N ++L FC+ +DI++ YS G +P
Sbjct: 187 VCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEP 226
>AB021654-1|BAA36169.1| 323|Homo sapiens DD2/bile acid-binding
protein/AKR1C2/3alpha-hydroxysteroid dehydrogenase type
3 protein.
Length = 323
Score = 180 bits (437), Expect = 2e-44
Identities = 101/240 (42%), Positives = 139/240 (57%), Gaps = 7/240 (2%)
Frame = +1
Query: 136 LSNGAKIPVIGIGTWKSKPGEVT-----QAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKT 300
L++G +PV+G GT+ P EV +AVK AI+ G+ HI A VY NE++VG AI++
Sbjct: 10 LNDGHFMPVLGFGTYA--PAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLAIRS 67
Query: 301 KIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDA 480
KI +G VKRED+F TSKLW+ HRP+LVR ALE SL+NL +DY+DLYLIH+P + K +
Sbjct: 68 KIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEE 127
Query: 481 IFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASV--KPG 654
+ P D +GKI F VD TW+A+E GL +S+GVSNFN + L+ IL+ + KP
Sbjct: 128 VIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKYKPV 187
Query: 655 H*PGRMPSVFKPXAIEAVLRRP*YYDNGVLPRWGXPDRPWAKPGDPHLMEDPKLKEIADR 834
F + + + PW P P L+EDP L +A +
Sbjct: 188 CNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKK 247
Score = 50.0 bits (114), Expect = 2e-05
Identities = 19/40 (47%), Positives = 26/40 (65%)
Frame = +2
Query: 653 VTNQVECHPYLNXKRLKQFCEDRDIMITXYSPXGXLPTDP 772
V NQVECHPY N ++L FC+ +DI++ YS G +P
Sbjct: 187 VCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEP 226
>D17793-1|BAA04619.2| 325|Homo sapiens KIAA0119 protein.
Length = 325
Score = 179 bits (435), Expect = 3e-44
Identities = 102/241 (42%), Positives = 141/241 (58%), Gaps = 8/241 (3%)
Frame = +1
Query: 136 LSNGAKIPVIGIGTW------KSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIK 297
L++G +PV+G GT+ +SK EVT K AI+ G+RHI A +Y NE++VG AI+
Sbjct: 12 LNDGHFMPVLGFGTYAPPEVPRSKALEVT---KLAIEAGFRHIDSAHLYNNEEQVGLAIR 68
Query: 298 TKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDD 477
+KI +G VKRED+F TSKLW+TFHRP+LVR ALE SL+ +DY+DLYLIH P + K +
Sbjct: 69 SKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLKPGE 128
Query: 478 AIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASV--KP 651
+ PTD +GK+ F VD TW+A+E GL +S+GVSNFN +QL+ IL+ + KP
Sbjct: 129 ELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKP 188
Query: 652 GH*PGRMPSVFKPXAIEAVLRRP*YYDNGVLPRWGXPDRPWAKPGDPHLMEDPKLKEIAD 831
F + + D+ W P P L+EDP L +A
Sbjct: 189 VCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGSQRDKRWVDPNSPVLLEDPVLCALAK 248
Query: 832 R 834
+
Sbjct: 249 K 249
Score = 48.0 bits (109), Expect = 9e-05
Identities = 18/34 (52%), Positives = 23/34 (67%)
Frame = +2
Query: 653 VTNQVECHPYLNXKRLKQFCEDRDIMITXYSPXG 754
V NQVECHPY N +L FC+ +DI++ YS G
Sbjct: 189 VCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALG 222
>BT007286-1|AAP35950.1| 323|Homo sapiens aldo-keto reductase family
1, member C3 (3-alpha hydroxysteroid dehydrogenase,
protein.
Length = 323
Score = 179 bits (435), Expect = 3e-44
Identities = 102/241 (42%), Positives = 141/241 (58%), Gaps = 8/241 (3%)
Frame = +1
Query: 136 LSNGAKIPVIGIGTW------KSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIK 297
L++G +PV+G GT+ +SK EVT K AI+ G+RHI A +Y NE++VG AI+
Sbjct: 10 LNDGHFMPVLGFGTYAPPEVPRSKALEVT---KLAIEAGFRHIDSAHLYNNEEQVGLAIR 66
Query: 298 TKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDD 477
+KI +G VKRED+F TSKLW+TFHRP+LVR ALE SL+ +DY+DLYLIH P + K +
Sbjct: 67 SKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLKPGE 126
Query: 478 AIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASV--KP 651
+ PTD +GK+ F VD TW+A+E GL +S+GVSNFN +QL+ IL+ + KP
Sbjct: 127 ELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKP 186
Query: 652 GH*PGRMPSVFKPXAIEAVLRRP*YYDNGVLPRWGXPDRPWAKPGDPHLMEDPKLKEIAD 831
F + + D+ W P P L+EDP L +A
Sbjct: 187 VCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGSQRDKRWVDPNSPVLLEDPVLCALAK 246
Query: 832 R 834
+
Sbjct: 247 K 247
Score = 48.0 bits (109), Expect = 9e-05
Identities = 18/34 (52%), Positives = 23/34 (67%)
Frame = +2
Query: 653 VTNQVECHPYLNXKRLKQFCEDRDIMITXYSPXG 754
V NQVECHPY N +L FC+ +DI++ YS G
Sbjct: 187 VCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALG 220
>BC019230-1|AAH19230.1| 323|Homo sapiens aldo-keto reductase family
1, member C3 (3-alpha hydroxysteroid dehydrogenase,
protein.
Length = 323
Score = 179 bits (435), Expect = 3e-44
Identities = 102/241 (42%), Positives = 141/241 (58%), Gaps = 8/241 (3%)
Frame = +1
Query: 136 LSNGAKIPVIGIGTW------KSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIK 297
L++G +PV+G GT+ +SK EVT K AI+ G+RHI A +Y NE++VG AI+
Sbjct: 10 LNDGHFMPVLGFGTYAPPEVPRSKALEVT---KLAIEAGFRHIDSAHLYNNEEQVGLAIR 66
Query: 298 TKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDD 477
+KI +G VKRED+F TSKLW+TFHRP+LVR ALE SL+ +DY+DLYLIH P + K +
Sbjct: 67 SKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLKPGE 126
Query: 478 AIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASV--KP 651
+ PTD +GK+ F VD TW+A+E GL +S+GVSNFN +QL+ IL+ + KP
Sbjct: 127 ELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKP 186
Query: 652 GH*PGRMPSVFKPXAIEAVLRRP*YYDNGVLPRWGXPDRPWAKPGDPHLMEDPKLKEIAD 831
F + + D+ W P P L+EDP L +A
Sbjct: 187 VCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGSQRDKRWVDPNSPVLLEDPVLCALAK 246
Query: 832 R 834
+
Sbjct: 247 K 247
Score = 48.0 bits (109), Expect = 9e-05
Identities = 18/34 (52%), Positives = 23/34 (67%)
Frame = +2
Query: 653 VTNQVECHPYLNXKRLKQFCEDRDIMITXYSPXG 754
V NQVECHPY N +L FC+ +DI++ YS G
Sbjct: 187 VCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALG 220
>BC001479-1|AAH01479.1| 323|Homo sapiens aldo-keto reductase family
1, member C3 (3-alpha hydroxysteroid dehydrogenase,
protein.
Length = 323
Score = 179 bits (435), Expect = 3e-44
Identities = 102/241 (42%), Positives = 141/241 (58%), Gaps = 8/241 (3%)
Frame = +1
Query: 136 LSNGAKIPVIGIGTW------KSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIK 297
L++G +PV+G GT+ +SK EVT K AI+ G+RHI A +Y NE++VG AI+
Sbjct: 10 LNDGHFMPVLGFGTYAPPEVPRSKALEVT---KLAIEAGFRHIDSAHLYNNEEQVGLAIR 66
Query: 298 TKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDD 477
+KI +G VKRED+F TSKLW+TFHRP+LVR ALE SL+ +DY+DLYLIH P + K +
Sbjct: 67 SKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLKPGE 126
Query: 478 AIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASV--KP 651
+ PTD +GK+ F VD TW+A+E GL +S+GVSNFN +QL+ IL+ + KP
Sbjct: 127 ELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKP 186
Query: 652 GH*PGRMPSVFKPXAIEAVLRRP*YYDNGVLPRWGXPDRPWAKPGDPHLMEDPKLKEIAD 831
F + + D+ W P P L+EDP L +A
Sbjct: 187 VCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGSQRDKRWVDPNSPVLLEDPVLCALAK 246
Query: 832 R 834
+
Sbjct: 247 K 247
Score = 48.0 bits (109), Expect = 9e-05
Identities = 18/34 (52%), Positives = 23/34 (67%)
Frame = +2
Query: 653 VTNQVECHPYLNXKRLKQFCEDRDIMITXYSPXG 754
V NQVECHPY N +L FC+ +DI++ YS G
Sbjct: 187 VCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALG 220
>AL391427-4|CAI14729.1| 323|Homo sapiens aldo-keto reductase family
1, member C3 (3-alpha hydroxysteroid dehydrogenase,
protein.
Length = 323
Score = 179 bits (435), Expect = 3e-44
Identities = 102/241 (42%), Positives = 141/241 (58%), Gaps = 8/241 (3%)
Frame = +1
Query: 136 LSNGAKIPVIGIGTW------KSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIK 297
L++G +PV+G GT+ +SK EVT K AI+ G+RHI A +Y NE++VG AI+
Sbjct: 10 LNDGHFMPVLGFGTYAPPEVPRSKALEVT---KLAIEAGFRHIDSAHLYNNEEQVGLAIR 66
Query: 298 TKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDD 477
+KI +G VKRED+F TSKLW+TFHRP+LVR ALE SL+ +DY+DLYLIH P + K +
Sbjct: 67 SKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLKPGE 126
Query: 478 AIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASV--KP 651
+ PTD +GK+ F VD TW+A+E GL +S+GVSNFN +QL+ IL+ + KP
Sbjct: 127 ELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKP 186
Query: 652 GH*PGRMPSVFKPXAIEAVLRRP*YYDNGVLPRWGXPDRPWAKPGDPHLMEDPKLKEIAD 831
F + + D+ W P P L+EDP L +A
Sbjct: 187 VCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGSQRDKRWVDPNSPVLLEDPVLCALAK 246
Query: 832 R 834
+
Sbjct: 247 K 247
Score = 48.0 bits (109), Expect = 9e-05
Identities = 18/34 (52%), Positives = 23/34 (67%)
Frame = +2
Query: 653 VTNQVECHPYLNXKRLKQFCEDRDIMITXYSPXG 754
V NQVECHPY N +L FC+ +DI++ YS G
Sbjct: 187 VCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALG 220
>AB032157-1|BAA92892.1| 323|Homo sapiens prostaglandin F synthase
protein.
Length = 323
Score = 179 bits (435), Expect = 3e-44
Identities = 102/241 (42%), Positives = 141/241 (58%), Gaps = 8/241 (3%)
Frame = +1
Query: 136 LSNGAKIPVIGIGTW------KSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIK 297
L++G +PV+G GT+ +SK EVT K AI+ G+RHI A +Y NE++VG AI+
Sbjct: 10 LNDGHFMPVLGFGTYAPPEVPRSKALEVT---KLAIEAGFRHIDSAHLYNNEEQVGLAIR 66
Query: 298 TKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDD 477
+KI +G VKRED+F TSKLW+TFHRP+LVR ALE SL+ +DY+DLYLIH P + K +
Sbjct: 67 SKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLKPGE 126
Query: 478 AIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASV--KP 651
+ PTD +GK+ F VD TW+A+E GL +S+GVSNFN +QL+ IL+ + KP
Sbjct: 127 ELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKP 186
Query: 652 GH*PGRMPSVFKPXAIEAVLRRP*YYDNGVLPRWGXPDRPWAKPGDPHLMEDPKLKEIAD 831
F + + D+ W P P L+EDP L +A
Sbjct: 187 VCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGSQRDKRWVDPNSPVLLEDPVLCALAK 246
Query: 832 R 834
+
Sbjct: 247 K 247
Score = 48.0 bits (109), Expect = 9e-05
Identities = 18/34 (52%), Positives = 23/34 (67%)
Frame = +2
Query: 653 VTNQVECHPYLNXKRLKQFCEDRDIMITXYSPXG 754
V NQVECHPY N +L FC+ +DI++ YS G
Sbjct: 187 VCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALG 220
>AB018580-1|BAA88488.1| 323|Homo sapiens hluPGFS protein.
Length = 323
Score = 179 bits (435), Expect = 3e-44
Identities = 102/241 (42%), Positives = 141/241 (58%), Gaps = 8/241 (3%)
Frame = +1
Query: 136 LSNGAKIPVIGIGTW------KSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIK 297
L++G +PV+G GT+ +SK EVT K AI+ G+RHI A +Y NE++VG AI+
Sbjct: 10 LNDGHFMPVLGFGTYAPPEVPRSKALEVT---KLAIEAGFRHIDSAHLYNNEEQVGLAIR 66
Query: 298 TKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDD 477
+KI +G VKRED+F TSKLW+TFHRP+LVR ALE SL+ +DY+DLYLIH P + K +
Sbjct: 67 SKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLKPGE 126
Query: 478 AIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASV--KP 651
+ PTD +GK+ F VD TW+A+E GL +S+GVSNFN +QL+ IL+ + KP
Sbjct: 127 ELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKP 186
Query: 652 GH*PGRMPSVFKPXAIEAVLRRP*YYDNGVLPRWGXPDRPWAKPGDPHLMEDPKLKEIAD 831
F + + D+ W P P L+EDP L +A
Sbjct: 187 VCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGSQRDKRWVDPNSPVLLEDPVLCALAK 246
Query: 832 R 834
+
Sbjct: 247 K 247
Score = 48.0 bits (109), Expect = 9e-05
Identities = 18/34 (52%), Positives = 23/34 (67%)
Frame = +2
Query: 653 VTNQVECHPYLNXKRLKQFCEDRDIMITXYSPXG 754
V NQVECHPY N +L FC+ +DI++ YS G
Sbjct: 187 VCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALG 220
>S68288-1|AAD14011.1| 323|Homo sapiens chlordecone reductase
homolog protein.
Length = 323
Score = 176 bits (429), Expect = 2e-43
Identities = 101/241 (41%), Positives = 141/241 (58%), Gaps = 8/241 (3%)
Frame = +1
Query: 136 LSNGAKIPVIGIGTW------KSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIK 297
L++G +PV+G GT+ +SK EVT K AI+ G+RHI A +Y NE++VG AI+
Sbjct: 10 LNDGHFMPVLGFGTYAPPEVPRSKALEVT---KLAIEAGFRHIDSAHLYNNEEQVGLAIR 66
Query: 298 TKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDD 477
+KI +G V+RED+F TSKLW+TFHRP+LVR ALE SL+ +DY+DLYLIH P + K +
Sbjct: 67 SKIADGSVEREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLKPGE 126
Query: 478 AIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASV--KP 651
+ PTD +GK+ F VD TW+A+E GL +S+GVSNFN +QL+ IL+ + KP
Sbjct: 127 ELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEIILNKPGLKYKP 186
Query: 652 GH*PGRMPSVFKPXAIEAVLRRP*YYDNGVLPRWGXPDRPWAKPGDPHLMEDPKLKEIAD 831
F + + D+ W P P L+EDP L +A
Sbjct: 187 VCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGSQRDKRWVDPNSPVLLEDPVLCALAK 246
Query: 832 R 834
+
Sbjct: 247 K 247
Score = 48.0 bits (109), Expect = 9e-05
Identities = 18/34 (52%), Positives = 23/34 (67%)
Frame = +2
Query: 653 VTNQVECHPYLNXKRLKQFCEDRDIMITXYSPXG 754
V NQVECHPY N +L FC+ +DI++ YS G
Sbjct: 187 VCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALG 220
>L43839-1|AAB41916.1| 323|Homo sapiens 3-alpha-hydroxysteroid
dehydrogenase protein.
Length = 323
Score = 175 bits (427), Expect = 3e-43
Identities = 101/241 (41%), Positives = 140/241 (58%), Gaps = 8/241 (3%)
Frame = +1
Query: 136 LSNGAKIPVIGIGTW------KSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIK 297
L++G +PV+G GT+ +SK EVT K AI+ G+RHI A +Y NE++VG AI+
Sbjct: 10 LNDGHFMPVLGFGTYAPPEVPRSKALEVT---KLAIEAGFRHIDSAHLYNNEEQVGLAIR 66
Query: 298 TKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDD 477
+KI +G V RED+F TSKLW+TFHRP+LVR ALE SL+ +DY+DLYLIH P + K +
Sbjct: 67 SKIADGSVMREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLKPGE 126
Query: 478 AIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASV--KP 651
+ PTD +GK+ F VD TW+A+E GL +S+GVSNFN +QL+ IL+ + KP
Sbjct: 127 ELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEIILNKPGLKYKP 186
Query: 652 GH*PGRMPSVFKPXAIEAVLRRP*YYDNGVLPRWGXPDRPWAKPGDPHLMEDPKLKEIAD 831
F + + D+ W P P L+EDP L +A
Sbjct: 187 VCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGSQRDKRWVDPNSPVLLEDPVLCALAK 246
Query: 832 R 834
+
Sbjct: 247 K 247
Score = 48.0 bits (109), Expect = 9e-05
Identities = 18/34 (52%), Positives = 23/34 (67%)
Frame = +2
Query: 653 VTNQVECHPYLNXKRLKQFCEDRDIMITXYSPXG 754
V NQVECHPY N +L FC+ +DI++ YS G
Sbjct: 187 VCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALG 220
>AF149416-1|AAF07272.2| 323|Homo sapiens 3-alpha hydroxysteroid
dehydrogenase type IIb protein.
Length = 323
Score = 174 bits (424), Expect = 6e-43
Identities = 97/238 (40%), Positives = 138/238 (57%), Gaps = 5/238 (2%)
Frame = +1
Query: 136 LSNGAKIPVIGIGTWKSKPGEVTQAV---KDAIDIGYRHIXCAFVYGNEKEVGEAIKTKI 306
L++G +PV+G GT+ ++A+ K AI+ G+RHI A +Y NE++VG AI++KI
Sbjct: 10 LNDGHFMPVLGFGTYAPPEVPRSKALEVSKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKI 69
Query: 307 QEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIF 486
+G VKRED+F TSKLW+T HRP+LVR ALE SL+ +DY+DLYLIH P + K + +
Sbjct: 70 ADGSVKREDIFYTSKLWSTSHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLKPGEELS 129
Query: 487 PTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASV--KPGH* 660
PTD +GK+ F VD TW+A+E GL +S+GVSNFN +QL+ IL+ + KP
Sbjct: 130 PTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCN 189
Query: 661 PGRMPSVFKPXAIEAVLRRP*YYDNGVLPRWGXPDRPWAKPGDPHLMEDPKLKEIADR 834
F + + D+ W P P L+EDP L +A +
Sbjct: 190 QVECHPYFNRSKLLDFCKSKDIVLVAYSALGSQRDKRWVDPNSPVLLEDPVLCALAKK 247
Score = 48.0 bits (109), Expect = 9e-05
Identities = 18/34 (52%), Positives = 23/34 (67%)
Frame = +2
Query: 653 VTNQVECHPYLNXKRLKQFCEDRDIMITXYSPXG 754
V NQVECHPY N +L FC+ +DI++ YS G
Sbjct: 187 VCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALG 220
>AL355480-2|CAI22458.1| 147|Homo sapiens aldo-keto reductase family
1, member A1 (aldehydela) protein.
Length = 147
Score = 174 bits (423), Expect = 9e-43
Identities = 77/140 (55%), Positives = 101/140 (72%), Gaps = 1/140 (0%)
Frame = +1
Query: 136 LSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQEG 315
L G K+P+IG+GTWKS+PG+V AVK A+ +GYRHI CA +YGNE E+GEA+K + G
Sbjct: 8 LHTGQKMPLIGLGTWKSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALKEDVGPG 67
Query: 316 -VVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPT 492
V RE+LF+TSKLWNT H P+ V AL +L +L ++YLDLYL+HWP A++ D FP
Sbjct: 68 KAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDNPFPK 127
Query: 493 DADGKIQFSDVDYVDTWKAL 552
+ADG I + Y +TWKAL
Sbjct: 128 NADGTICYDSTHYKETWKAL 147
>D26124-1|BAA05121.1| 306|Homo sapiens dihydrodiol dehydrogenase
isoform DD1 protein.
Length = 306
Score = 173 bits (422), Expect = 1e-42
Identities = 98/232 (42%), Positives = 133/232 (57%), Gaps = 7/232 (3%)
Frame = +1
Query: 160 VIGIGTWKSKPGEVT-----QAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQEGVVK 324
V+G GT+ P EV +A K AI+ G+RHI A +Y NE++VG AI++KI +G VK
Sbjct: 1 VLGFGTYA--PAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVK 58
Query: 325 REDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTDADG 504
RED+F TSKLW HRP+LVR ALE SL+NL +DY+DLYLIH+P + K + + P D +G
Sbjct: 59 REDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENG 118
Query: 505 KIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASV--KPGH*PGRMPS 678
KI F VD TW+A+E GL +S+GVSNFN +QL+ IL+ + KP
Sbjct: 119 KILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHP 178
Query: 679 VFKPXAIEAVLRRP*YYDNGVLPRWGXPDRPWAKPGDPHLMEDPKLKEIADR 834
F + + + PW P P L+EDP L +A +
Sbjct: 179 YFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKK 230
Score = 50.0 bits (114), Expect = 2e-05
Identities = 19/40 (47%), Positives = 26/40 (65%)
Frame = +2
Query: 653 VTNQVECHPYLNXKRLKQFCEDRDIMITXYSPXGXLPTDP 772
V NQVECHPY N ++L FC+ +DI++ YS G +P
Sbjct: 170 VCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEP 209
>DQ269985-1|ABB76132.1| 323|Homo sapiens type II 3a-hydroxysteroid
dehydrogenase variant protein.
Length = 323
Score = 173 bits (421), Expect = 1e-42
Identities = 98/240 (40%), Positives = 137/240 (57%), Gaps = 7/240 (2%)
Frame = +1
Query: 136 LSNGAKIPVIGIGTWKSKPGEVT-----QAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKT 300
L++G +PV+G GT+ P EV +A K AI+ G+RHI A +Y NE++VG A+++
Sbjct: 10 LNDGHFMPVLGFGTYA--PAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAVRS 67
Query: 301 KIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDA 480
KI +G VKRED+F TSKLW HRP+LVR ALE SL+ +DY+DLYLIH P + K +
Sbjct: 68 KIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKKAQLDYVDLYLIHSPMSLKPGEE 127
Query: 481 IFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASV--KPG 654
+ PTD +GK+ F VD TW+A+E GL +S+GVSNFN +QL+ IL+ + KP
Sbjct: 128 LSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPV 187
Query: 655 H*PGRMPSVFKPXAIEAVLRRP*YYDNGVLPRWGXPDRPWAKPGDPHLMEDPKLKEIADR 834
F + + D+ W P P L+EDP L +A +
Sbjct: 188 CNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGSQRDKRWVDPNSPVLLEDPVLCALAKK 247
Score = 48.0 bits (109), Expect = 9e-05
Identities = 18/34 (52%), Positives = 23/34 (67%)
Frame = +2
Query: 653 VTNQVECHPYLNXKRLKQFCEDRDIMITXYSPXG 754
V NQVECHPY N +L FC+ +DI++ YS G
Sbjct: 187 VCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALG 220
>S68290-1|AAD14012.1| 320|Homo sapiens chlordecone reductase
homolog protein.
Length = 320
Score = 171 bits (417), Expect = 5e-42
Identities = 99/240 (41%), Positives = 135/240 (56%), Gaps = 7/240 (2%)
Frame = +1
Query: 136 LSNGAKIPVIGIGTWKSKPGEVT-----QAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKT 300
L++G +PV+G GT+ P EV +A K AI+ G+RHI A +Y NE++VG AI++
Sbjct: 7 LNDGHFMPVLGFGTYA--PAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRS 64
Query: 301 KIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDA 480
KI +G VKRED+F TSKLW HRP+L R ALE SL+NL +DY+DLYLIH+P + K +
Sbjct: 65 KIADGSVKREDIFYTSKLWCNSHRPELDRPALERSLKNLQLDYVDLYLIHFPVSVKPGEE 124
Query: 481 IFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILD--NASVKPG 654
+ P D +GKI F VD TW+A+E L +S+GVSNFN L+ IL+ VKP
Sbjct: 125 VIPKDENGKILFDTVDLCATWEAVEKCKDAELAKSIGVSNFNRSTLEMILNKPGLQVKPV 184
Query: 655 H*PGRMPSVFKPXAIEAVLRRP*YYDNGVLPRWGXPDRPWAKPGDPHLMEDPKLKEIADR 834
F + + + PW P P L+EDP L +A +
Sbjct: 185 CNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSLREEPWVDPNSPVLLEDPVLCALAKK 244
Score = 52.8 bits (121), Expect = 3e-06
Identities = 20/40 (50%), Positives = 27/40 (67%)
Frame = +2
Query: 653 VTNQVECHPYLNXKRLKQFCEDRDIMITXYSPXGXLPTDP 772
V NQVECHPY N ++L FC+ +DI++ YS G L +P
Sbjct: 184 VCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSLREEP 223
>AB045829-1|BAA99542.1| 323|Homo sapiens 3alpha-hydroxysteroid
dehydrogenase variant protein.
Length = 323
Score = 168 bits (408), Expect = 6e-41
Identities = 82/174 (47%), Positives = 117/174 (67%), Gaps = 3/174 (1%)
Frame = +1
Query: 136 LSNGAKIPVIGIGTWKSKPGEVTQAV---KDAIDIGYRHIXCAFVYGNEKEVGEAIKTKI 306
L++G +PV+G GT+ +AV K AI+ G+RHI A++Y NE++VG AI++KI
Sbjct: 10 LNDGHFMPVLGFGTYAPPEVPRNRAVEVTKLAIEAGFRHIDSAYLYNNEEQVGLAIRSKI 69
Query: 307 QEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIF 486
+G VKRED+F TSKLW TF +P +V+ ALE SL+ L +DY+DLYL+H+P A K +
Sbjct: 70 ADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALKPGETPL 129
Query: 487 PTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVK 648
P D +GK+ F VD TW+ +E GL +S+GVSNFN +QL+ IL+ +K
Sbjct: 130 PKDENGKVIFDTVDLCATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILNKPGLK 183
Score = 47.6 bits (108), Expect = 1e-04
Identities = 18/34 (52%), Positives = 24/34 (70%)
Frame = +2
Query: 653 VTNQVECHPYLNXKRLKQFCEDRDIMITXYSPXG 754
V NQVECHPYLN +L FC+ +DI++ +S G
Sbjct: 187 VCNQVECHPYLNQSKLLDFCKSKDIVLVAHSALG 220
>S68287-1|AAD14010.1| 323|Homo sapiens chlordecone reductase
protein.
Length = 323
Score = 167 bits (407), Expect = 7e-41
Identities = 82/174 (47%), Positives = 117/174 (67%), Gaps = 3/174 (1%)
Frame = +1
Query: 136 LSNGAKIPVIGIGTWKSKPGEVTQAV---KDAIDIGYRHIXCAFVYGNEKEVGEAIKTKI 306
L++G +PV+G GT+ +AV K AI+ G+RHI A++Y NE++VG AI++KI
Sbjct: 10 LNDGHFMPVLGFGTYAPPEVPRNRAVEVTKLAIEAGFRHIDSAYLYNNEEQVGLAIRSKI 69
Query: 307 QEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIF 486
+G VKRED+F TSKLW TF +P +V+ ALE SL+ L +DY+DLYL+H+P A K +
Sbjct: 70 ADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALKPGETPL 129
Query: 487 PTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVK 648
P D +GK+ F VD TW+ +E GL +S+GVSNFN +QL+ IL+ +K
Sbjct: 130 PKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILNKPGLK 183
Score = 47.6 bits (108), Expect = 1e-04
Identities = 18/34 (52%), Positives = 24/34 (70%)
Frame = +2
Query: 653 VTNQVECHPYLNXKRLKQFCEDRDIMITXYSPXG 754
V NQVECHPYLN +L FC+ +DI++ +S G
Sbjct: 187 VCNQVECHPYLNQSKLLDFCKSKDIVLVAHSALG 220
>D26125-1|BAA05122.1| 321|Homo sapiens 3
alpha-hydroxysteroid/dihydrodiol dehydrogenase DD4
protein.
Length = 321
Score = 167 bits (407), Expect = 7e-41
Identities = 82/174 (47%), Positives = 117/174 (67%), Gaps = 3/174 (1%)
Frame = +1
Query: 136 LSNGAKIPVIGIGTWKSKPGEVTQAV---KDAIDIGYRHIXCAFVYGNEKEVGEAIKTKI 306
L++G +PV+G GT+ +AV K AI+ G+RHI A++Y NE++VG AI++KI
Sbjct: 8 LNDGHFMPVLGFGTYAPPEVPRNRAVEVTKLAIEAGFRHIDSAYLYNNEEQVGLAIRSKI 67
Query: 307 QEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIF 486
+G VKRED+F TSKLW TF +P +V+ ALE SL+ L +DY+DLYL+H+P A K +
Sbjct: 68 ADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALKPGETPL 127
Query: 487 PTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVK 648
P D +GK+ F VD TW+ +E GL +S+GVSNFN +QL+ IL+ +K
Sbjct: 128 PKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILNKPGLK 181
Score = 47.6 bits (108), Expect = 1e-04
Identities = 18/34 (52%), Positives = 24/34 (70%)
Frame = +2
Query: 653 VTNQVECHPYLNXKRLKQFCEDRDIMITXYSPXG 754
V NQVECHPYLN +L FC+ +DI++ +S G
Sbjct: 185 VCNQVECHPYLNQSKLLDFCKSKDIVLVAHSALG 218
>AL355303-2|CAI14202.1| 323|Homo sapiens aldo-keto reductase family
1, member C4 (chlordecone reductase; 3-alpha hydroxy
protein.
Length = 323
Score = 167 bits (407), Expect = 7e-41
Identities = 82/174 (47%), Positives = 117/174 (67%), Gaps = 3/174 (1%)
Frame = +1
Query: 136 LSNGAKIPVIGIGTWKSKPGEVTQAV---KDAIDIGYRHIXCAFVYGNEKEVGEAIKTKI 306
L++G +PV+G GT+ +AV K AI+ G+RHI A++Y NE++VG AI++KI
Sbjct: 10 LNDGHFMPVLGFGTYAPPEVPRNRAVEVTKLAIEAGFRHIDSAYLYNNEEQVGLAIRSKI 69
Query: 307 QEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIF 486
+G VKRED+F TSKLW TF +P +V+ ALE SL+ L +DY+DLYL+H+P A K +
Sbjct: 70 ADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALKPGETPL 129
Query: 487 PTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVK 648
P D +GK+ F VD TW+ +E GL +S+GVSNFN +QL+ IL+ +K
Sbjct: 130 PKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILNKPGLK 183
Score = 47.6 bits (108), Expect = 1e-04
Identities = 18/34 (52%), Positives = 24/34 (70%)
Frame = +2
Query: 653 VTNQVECHPYLNXKRLKQFCEDRDIMITXYSPXG 754
V NQVECHPYLN +L FC+ +DI++ +S G
Sbjct: 187 VCNQVECHPYLNQSKLLDFCKSKDIVLVAHSALG 220
>AB032163-1|BAA92893.1| 323|Homo sapiens dihydrodiol dehydrogenase
4 protein.
Length = 323
Score = 167 bits (407), Expect = 7e-41
Identities = 82/174 (47%), Positives = 117/174 (67%), Gaps = 3/174 (1%)
Frame = +1
Query: 136 LSNGAKIPVIGIGTWKSKPGEVTQAV---KDAIDIGYRHIXCAFVYGNEKEVGEAIKTKI 306
L++G +PV+G GT+ +AV K AI+ G+RHI A++Y NE++VG AI++KI
Sbjct: 10 LNDGHFMPVLGFGTYAPPEVPRNRAVEVTKLAIEAGFRHIDSAYLYNNEEQVGLAIRSKI 69
Query: 307 QEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIF 486
+G VKRED+F TSKLW TF +P +V+ ALE SL+ L +DY+DLYL+H+P A K +
Sbjct: 70 ADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALKPGETPL 129
Query: 487 PTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVK 648
P D +GK+ F VD TW+ +E GL +S+GVSNFN +QL+ IL+ +K
Sbjct: 130 PKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILNKPGLK 183
Score = 47.6 bits (108), Expect = 1e-04
Identities = 18/34 (52%), Positives = 24/34 (70%)
Frame = +2
Query: 653 VTNQVECHPYLNXKRLKQFCEDRDIMITXYSPXG 754
V NQVECHPYLN +L FC+ +DI++ +S G
Sbjct: 187 VCNQVECHPYLNQSKLLDFCKSKDIVLVAHSALG 220
>AB031085-1|BAA92885.1| 323|Homo sapiens dihydrodiol dehydrogenase
4 protein.
Length = 323
Score = 167 bits (407), Expect = 7e-41
Identities = 82/174 (47%), Positives = 117/174 (67%), Gaps = 3/174 (1%)
Frame = +1
Query: 136 LSNGAKIPVIGIGTWKSKPGEVTQAV---KDAIDIGYRHIXCAFVYGNEKEVGEAIKTKI 306
L++G +PV+G GT+ +AV K AI+ G+RHI A++Y NE++VG AI++KI
Sbjct: 10 LNDGHFMPVLGFGTYAPPEVPRNRAVEVTKLAIEAGFRHIDSAYLYNNEEQVGLAIRSKI 69
Query: 307 QEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIF 486
+G VKRED+F TSKLW TF +P +V+ ALE SL+ L +DY+DLYL+H+P A K +
Sbjct: 70 ADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALKPGETPL 129
Query: 487 PTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVK 648
P D +GK+ F VD TW+ +E GL +S+GVSNFN +QL+ IL+ +K
Sbjct: 130 PKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILNKPGLK 183
Score = 47.6 bits (108), Expect = 1e-04
Identities = 18/34 (52%), Positives = 24/34 (70%)
Frame = +2
Query: 653 VTNQVECHPYLNXKRLKQFCEDRDIMITXYSPXG 754
V NQVECHPYLN +L FC+ +DI++ +S G
Sbjct: 187 VCNQVECHPYLNQSKLLDFCKSKDIVLVAHSALG 220
>BC020744-1|AAH20744.1| 323|Homo sapiens aldo-keto reductase family
1, member C4 (chlordecone reductase; 3-alpha hydroxy
protein.
Length = 323
Score = 167 bits (406), Expect = 1e-40
Identities = 82/174 (47%), Positives = 117/174 (67%), Gaps = 3/174 (1%)
Frame = +1
Query: 136 LSNGAKIPVIGIGTWKSKPGEVTQAV---KDAIDIGYRHIXCAFVYGNEKEVGEAIKTKI 306
L++G +PV+G GT+ +AV K AI+ G+RHI A++Y NE++VG AI++KI
Sbjct: 10 LNDGHFMPVLGFGTYAPPEVPRNRAVEVTKLAIEAGFRHIDSAYLYNNEEQVGLAIRSKI 69
Query: 307 QEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIF 486
+G VKRED+F TSKLW TF +P +V+ ALE SL+ L +DY+DLYL+H+P A K +
Sbjct: 70 ADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALKPGETPL 129
Query: 487 PTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVK 648
P D +GK+ F VD TW+ +E GL +S+GVSNFN +QL+ IL+ +K
Sbjct: 130 PKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNYRQLEMILNKPGLK 183
Score = 47.6 bits (108), Expect = 1e-04
Identities = 18/34 (52%), Positives = 24/34 (70%)
Frame = +2
Query: 653 VTNQVECHPYLNXKRLKQFCEDRDIMITXYSPXG 754
V NQVECHPYLN +L FC+ +DI++ +S G
Sbjct: 187 VCNQVECHPYLNQSKLLDFCKSKDIVLVAHSALG 220
>M33375-1|AAA35658.1| 308|Homo sapiens protein ( Human chlordecone
reductase mRNA, complete cds. ).
Length = 308
Score = 165 bits (400), Expect = 5e-40
Identities = 80/168 (47%), Positives = 113/168 (67%), Gaps = 3/168 (1%)
Frame = +1
Query: 154 IPVIGIGTWKSKPGEVTQAV---KDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQEGVVK 324
+PV+G GT+ +AV K AI+ G+RHI A++Y NE++VG AI++KI +G VK
Sbjct: 1 MPVLGFGTYAPPEVPRNRAVEVTKLAIEAGFRHIDSAYLYNNEEQVGLAIRSKIADGSVK 60
Query: 325 REDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTDADG 504
RED+F TSKLW TF +P +V+ ALE SL+ L +DY+DLYL+H+P A K + P D +G
Sbjct: 61 REDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALKPGETPLPKDENG 120
Query: 505 KIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVK 648
K+ F VD TW+ +E GL +S+GVSNFN +QL+ IL+ +K
Sbjct: 121 KVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILNKPGLK 168
Score = 47.6 bits (108), Expect = 1e-04
Identities = 18/34 (52%), Positives = 24/34 (70%)
Frame = +2
Query: 653 VTNQVECHPYLNXKRLKQFCEDRDIMITXYSPXG 754
V NQVECHPYLN +L FC+ +DI++ +S G
Sbjct: 172 VCNQVECHPYLNQSKLLDFCKSKDIVLVAHSALG 205
>AL713867-3|CAI16410.1| 247|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 247
Score = 146 bits (355), Expect = 1e-34
Identities = 80/188 (42%), Positives = 107/188 (56%), Gaps = 2/188 (1%)
Frame = +1
Query: 277 EVGEAIKTKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWP 456
EVG AI++KI +G VKRED+F TSKLW HRP+LVR ALE SL+NL +DY+DLYLIH+P
Sbjct: 26 EVGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFP 85
Query: 457 QAYKEDDAIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDN 636
+ K + + P D +GKI F VD TW+A+E GL +S+GVSNFN +QL+ IL+
Sbjct: 86 VSVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNK 145
Query: 637 ASV--KPGH*PGRMPSVFKPXAIEAVLRRP*YYDNGVLPRWGXPDRPWAKPGDPHLMEDP 810
+ KP F + + + PW P P L+EDP
Sbjct: 146 PGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDP 205
Query: 811 KLKEIADR 834
L +A +
Sbjct: 206 VLCALAKK 213
Score = 50.0 bits (114), Expect = 2e-05
Identities = 19/40 (47%), Positives = 26/40 (65%)
Frame = +2
Query: 653 VTNQVECHPYLNXKRLKQFCEDRDIMITXYSPXGXLPTDP 772
V NQVECHPY N ++L FC+ +DI++ YS G +P
Sbjct: 153 VCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEP 192
>AB040822-1|BAC54567.1| 222|Homo sapiens aldo-keto reductase
related protein 3 protein.
Length = 222
Score = 144 bits (349), Expect = 8e-34
Identities = 71/152 (46%), Positives = 94/152 (61%), Gaps = 19/152 (12%)
Frame = +1
Query: 154 IPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKIQEGVVKRED 333
IP +G+ +WK+ PG+VT+AVK+AID GYRH CA+ Y NE+EVG I+ KI+EG V+RED
Sbjct: 4 IPAVGLSSWKASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEGAVRRED 63
Query: 334 LFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKE---------DDAIF 486
LFI +KLW T H+ LV A SL+ L ++YLDLYLIHWP +K + F
Sbjct: 64 LFIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPMGFKPPHPEWIMSCSELSF 123
Query: 487 ----------PTDADGKIQFSDVDYVDTWKAL 552
P D + SD D++DTW+ L
Sbjct: 124 CLSHPRVQDLPLDESNMVIPSDTDFLDTWEIL 155
>AL391427-2|CAI14727.1| 302|Homo sapiens aldo-keto reductase family
1, member C-like 1 protein.
Length = 302
Score = 132 bits (319), Expect = 3e-30
Identities = 66/141 (46%), Positives = 93/141 (65%), Gaps = 4/141 (2%)
Frame = +1
Query: 136 LSNGAKIPVIGIGTWK---SKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKI 306
L++G +PV+G GT+ + + +A K AID+G+RHI A++Y NE+EVG+AI KI
Sbjct: 13 LNDGPFMPVLGFGTYAPDHTPKSQAAEATKVAIDVGFRHIDSAYLYQNEEEVGQAIWEKI 72
Query: 307 QEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKE-DDAI 483
+G VKRE++F T KLW TF R +LV ALE SL+ L DY+DL++IH P A K+ +
Sbjct: 73 ADGTVKREEIFYTIKLWATFFRAELVHPALERSLKKLGPDYVDLFIIHVPFAMKQPGKEL 132
Query: 484 FPTDADGKIQFSDVDYVDTWK 546
P DA G+I V+ DTW+
Sbjct: 133 LPKDASGEIILETVELCDTWE 153
Score = 45.6 bits (103), Expect = 5e-04
Identities = 20/39 (51%), Positives = 26/39 (66%)
Frame = +2
Query: 638 PL*NQVTNQVECHPYLNXKRLKQFCEDRDIMITXYSPXG 754
P NQV VECHPYLN +L +FC+ +DI++ YS G
Sbjct: 167 PTCNQV---VECHPYLNQSKLLEFCKSKDIVLVAYSALG 202
Score = 31.9 bits (69), Expect = 6.7
Identities = 13/31 (41%), Positives = 17/31 (54%)
Frame = +1
Query: 763 DRPWAKPGDPHLMEDPKLKEIADRLGKXAAQ 855
D W P PHL+E+P LK IA + + Q
Sbjct: 206 DPQWVDPDCPHLLEEPILKSIAKKHSRSPGQ 236
>AL355303-1|CAI14201.1| 302|Homo sapiens aldo-keto reductase family
1, member C-like 1 protein.
Length = 302
Score = 132 bits (319), Expect = 3e-30
Identities = 66/141 (46%), Positives = 93/141 (65%), Gaps = 4/141 (2%)
Frame = +1
Query: 136 LSNGAKIPVIGIGTWK---SKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKI 306
L++G +PV+G GT+ + + +A K AID+G+RHI A++Y NE+EVG+AI KI
Sbjct: 13 LNDGPFMPVLGFGTYAPDHTPKSQAAEATKVAIDVGFRHIDSAYLYQNEEEVGQAIWEKI 72
Query: 307 QEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKE-DDAI 483
+G VKRE++F T KLW TF R +LV ALE SL+ L DY+DL++IH P A K+ +
Sbjct: 73 ADGTVKREEIFYTIKLWATFFRAELVHPALERSLKKLGPDYVDLFIIHVPFAMKQPGKEL 132
Query: 484 FPTDADGKIQFSDVDYVDTWK 546
P DA G+I V+ DTW+
Sbjct: 133 LPKDASGEIILETVELCDTWE 153
Score = 45.6 bits (103), Expect = 5e-04
Identities = 20/39 (51%), Positives = 26/39 (66%)
Frame = +2
Query: 638 PL*NQVTNQVECHPYLNXKRLKQFCEDRDIMITXYSPXG 754
P NQV VECHPYLN +L +FC+ +DI++ YS G
Sbjct: 167 PTCNQV---VECHPYLNQSKLLEFCKSKDIVLVAYSALG 202
Score = 31.9 bits (69), Expect = 6.7
Identities = 13/31 (41%), Positives = 17/31 (54%)
Frame = +1
Query: 763 DRPWAKPGDPHLMEDPKLKEIADRLGKXAAQ 855
D W P PHL+E+P LK IA + + Q
Sbjct: 206 DPQWVDPDCPHLLEEPILKSIAKKHSRSPGQ 236
>BC101205-1|AAI01206.1| 129|Homo sapiens aldo-keto reductase family
1, member C-like 1 protein.
Length = 129
Score = 116 bits (279), Expect = 2e-25
Identities = 57/114 (50%), Positives = 79/114 (69%), Gaps = 3/114 (2%)
Frame = +1
Query: 136 LSNGAKIPVIGIGTWK---SKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKI 306
L++G +PV+G GT+ + + +A K AID+G+RHI A++Y NE+EVG+AI KI
Sbjct: 13 LNDGPFMPVLGFGTYAPDHTPKSQAAEATKVAIDVGFRHIDSAYLYQNEEEVGQAIWEKI 72
Query: 307 QEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYK 468
+G VKRE++F T KLW TF R +LV ALE SL+ L DY+DL++IH P A K
Sbjct: 73 ADGTVKREEIFYTIKLWATFFRAELVHPALERSLKKLGPDYVDLFIIHVPFAMK 126
>BC101204-1|AAI01205.1| 129|Homo sapiens aldo-keto reductase family
1, member C-like 1 protein.
Length = 129
Score = 116 bits (279), Expect = 2e-25
Identities = 57/114 (50%), Positives = 79/114 (69%), Gaps = 3/114 (2%)
Frame = +1
Query: 136 LSNGAKIPVIGIGTWK---SKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKI 306
L++G +PV+G GT+ + + +A K AID+G+RHI A++Y NE+EVG+AI KI
Sbjct: 13 LNDGPFMPVLGFGTYAPDHTPKSQAAEATKVAIDVGFRHIDSAYLYQNEEEVGQAIWEKI 72
Query: 307 QEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYK 468
+G VKRE++F T KLW TF R +LV ALE SL+ L DY+DL++IH P A K
Sbjct: 73 ADGTVKREEIFYTIKLWATFFRAELVHPALERSLKKLGPDYVDLFIIHVPFAMK 126
>AK131335-1|BAD18494.1| 129|Homo sapiens protein ( Homo sapiens
cDNA FLJ16347 fis, clone TESTI2036288, moderately
similar to PROSTAGLANDIN-F SYNTHASE 1 (EC 1.1.1.188). ).
Length = 129
Score = 116 bits (279), Expect = 2e-25
Identities = 57/114 (50%), Positives = 79/114 (69%), Gaps = 3/114 (2%)
Frame = +1
Query: 136 LSNGAKIPVIGIGTWK---SKPGEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKI 306
L++G +PV+G GT+ + + +A K AID+G+RHI A++Y NE+EVG+AI KI
Sbjct: 13 LNDGPFMPVLGFGTYAPDHTPKSQAAEATKVAIDVGFRHIDSAYLYQNEEEVGQAIWEKI 72
Query: 307 QEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYK 468
+G VKRE++F T KLW TF R +LV ALE SL+ L DY+DL++IH P A K
Sbjct: 73 ADGTVKREEIFYTIKLWATFFRAELVHPALERSLKKLGPDYVDLFIIHVPFAMK 126
>AB037902-1|BAA92887.1| 130|Homo sapiens truncated aldo-keto
reductase protein.
Length = 130
Score = 116 bits (279), Expect = 2e-25
Identities = 52/110 (47%), Positives = 79/110 (71%), Gaps = 3/110 (2%)
Frame = +1
Query: 136 LSNGAKIPVIGIGTWKSKP---GEVTQAVKDAIDIGYRHIXCAFVYGNEKEVGEAIKTKI 306
L++G +P++G GT ++ V +AV+ AID+GYRHI A+ + NE+ +G+AI+ KI
Sbjct: 11 LNDGKFMPILGFGTSVARKVAMSNVEEAVQVAIDVGYRHIDSAYTHLNEEGIGQAIRKKI 70
Query: 307 QEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWP 456
G VKR+D+F T+K+W TF RP+LV+ LE+SL+ L + Y+DLYL H+P
Sbjct: 71 ANGTVKRKDIFYTTKVWGTFSRPELVQRGLEMSLKKLQLSYMDLYLFHFP 120
>AK058142-1|BAB71682.1| 146|Homo sapiens protein ( Homo sapiens
cDNA FLJ25413 fis, clone TST03402, highly similar to
3-OXO-5-BETA-STEROID 4-DEHYDROGENASE (EC 1.3.99.6). ).
Length = 146
Score = 58.4 bits (135), Expect = 7e-08
Identities = 28/63 (44%), Positives = 40/63 (63%)
Frame = +1
Query: 460 AYKEDDAIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNA 639
A+K D I+P D +GK + + TW+A+E GLV+SLGVSNFN +QL+ IL+
Sbjct: 2 AFKPGDEIYPRDENGKWLYHKSNLCATWEAMEACKDAGLVKSLGVSNFNRRQLELILNKP 61
Query: 640 SVK 648
+K
Sbjct: 62 GLK 64
Score = 52.0 bits (119), Expect = 6e-06
Identities = 20/34 (58%), Positives = 25/34 (73%)
Frame = +2
Query: 653 VTNQVECHPYLNXKRLKQFCEDRDIMITXYSPXG 754
V+NQVECHPY +L +FC+ DI+IT YSP G
Sbjct: 68 VSNQVECHPYFTQPKLLKFCQQHDIVITAYSPLG 101
>AB028065-1|BAA88489.1| 67|Homo sapiens prostaglandin F synthase
protein.
Length = 67
Score = 58.0 bits (134), Expect = 9e-08
Identities = 26/58 (44%), Positives = 38/58 (65%)
Frame = +1
Query: 475 DAIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVK 648
+ + PTD +GK+ F VD TW+A+E GL +S+GVSNFN +QL+ IL+ +K
Sbjct: 3 EELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLK 60
>AB037905-2|BAA92890.1| 45|Homo sapiens truncated aldo-keto
reductase protein.
Length = 45
Score = 50.4 bits (115), Expect = 2e-05
Identities = 19/35 (54%), Positives = 27/35 (77%)
Frame = +1
Query: 352 LWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWP 456
+W TF RP+LV+ LE+SL+ L + Y+DLYL H+P
Sbjct: 1 VWGTFSRPELVQRGLEMSLKKLQLSYMDLYLFHFP 35
>AK131252-1|BAD18431.1| 415|Homo sapiens protein ( Homo sapiens
cDNA FLJ16180 fis, clone BRHIP3000240, highly similar
to Homo sapiens potassium channel beta 2 subunit
(HKvbeta2.2) mRNA. ).
Length = 415
Score = 36.3 bits (80), Expect = 0.31
Identities = 39/174 (22%), Positives = 76/174 (43%), Gaps = 15/174 (8%)
Frame = +1
Query: 142 NGAKIPVIGIGTWKSKPGEVTQAVKD-----AIDIGYRHIXCAFVYGNEKEVGEAIKTKI 306
+G ++ +G+GTW + G++T + + A D G A VY K + I
Sbjct: 78 SGLRVSCLGLGTWVTFGGQITDEMAEQLMTLAYDNGINLFDTAEVYAAGK-AEVVLGNII 136
Query: 307 QEGVVKREDLFITSKL-W-------NTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQA 462
++ +R L IT+K+ W R ++ G L+ SL L ++Y+D+ + P
Sbjct: 137 KKKGWRRSSLVITTKIFWGGKAETERGLSRKHIIEG-LKASLERLQLEYVDVVFANRP-- 193
Query: 463 YKEDDAIFPTDADGKIQFSDVDYV--DTWKALEPLVCHGLVRSLGVSNFNSKQL 618
D P + D ++ +T +A+ ++ G+ G S ++S ++
Sbjct: 194 ----DPNTPMEGDPFSSSKSRTFIIEETVRAMTHVINQGMAMYWGTSRWSSMEI 243
>U33429-1|AAC50955.1| 367|Homo sapiens K+ channel beta 2 subunit
protein.
Length = 367
Score = 34.3 bits (75), Expect = 1.3
Identities = 30/118 (25%), Positives = 54/118 (45%), Gaps = 13/118 (11%)
Frame = +1
Query: 142 NGAKIPVIGIGTWKSKPGEVTQAVKD-----AIDIGYRHIXCAFVYGNEKEVGEAIKTKI 306
+G ++ +G+GTW + G++T + + A D G A VY K + I
Sbjct: 45 SGLRVSCLGLGTWVTFGGQITDEMAEQLMTLAYDNGINLFDTAEVYAAGK-AEVVLGNII 103
Query: 307 QEGVVKREDLFITSKL-W-------NTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWP 456
++ +R L IT+K+ W R ++ G L+ SL L ++Y+D+ + P
Sbjct: 104 KKKGWRRSSLVITTKIFWGGKAETERGLSRKHIIEG-LKASLERLQLEYVDVVFANRP 160
>L47665-1|AAC41926.1| 419|Homo sapiens K+ channel beta-subunit
protein.
Length = 419
Score = 34.3 bits (75), Expect = 1.3
Identities = 31/129 (24%), Positives = 61/129 (47%), Gaps = 13/129 (10%)
Frame = +1
Query: 115 TSVPVTTLS-NGAKIPVIGIGTWKSKPGEVTQAVKDAI-DIGYRHIXCAFVYGNEKEVGE 288
T +P L +G ++ +G+GTW + G+++ V + + I Y F G+
Sbjct: 87 TGMPHRNLGKSGLRVSCLGLGTWVTFGGQISDEVAERLMTIAYESGVNLFDTAEVYAAGK 146
Query: 289 A---IKTKIQEGVVKREDLFITSKLW--------NTFHRPDLVRGALEVSLRNLNIDYLD 435
A + + I++ +R L IT+KL+ R ++ G L+ SL+ L ++Y+D
Sbjct: 147 AEVILGSIIKKKGWRRSSLVITTKLYWGGKAETERGLSRKHIIEG-LKGSLQRLQLEYVD 205
Query: 436 LYLIHWPQA 462
+ + P +
Sbjct: 206 VVFANRPDS 214
>CR542287-1|CAG47082.1| 353|Homo sapiens KCNAB2 protein.
Length = 353
Score = 34.3 bits (75), Expect = 1.3
Identities = 30/118 (25%), Positives = 54/118 (45%), Gaps = 13/118 (11%)
Frame = +1
Query: 142 NGAKIPVIGIGTWKSKPGEVTQAVKD-----AIDIGYRHIXCAFVYGNEKEVGEAIKTKI 306
+G ++ +G+GTW + G++T + + A D G A VY K + I
Sbjct: 31 SGLRVSCLGLGTWVTFGGQITDEMAEQLMTLAYDNGINLFDTAEVYAAGK-AEVVLGNII 89
Query: 307 QEGVVKREDLFITSKL-W-------NTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWP 456
++ +R L IT+K+ W R ++ G L+ SL L ++Y+D+ + P
Sbjct: 90 KKKGWRRSSLVITTKIFWGGKAETERGLSRKHIIEG-LKASLERLQLEYVDVVFANRP 146
>BC130413-1|AAI30414.1| 367|Homo sapiens potassium voltage-gated
channel, shaker-related subfamily, beta member 2
protein.
Length = 367
Score = 34.3 bits (75), Expect = 1.3
Identities = 30/118 (25%), Positives = 54/118 (45%), Gaps = 13/118 (11%)
Frame = +1
Query: 142 NGAKIPVIGIGTWKSKPGEVTQAVKD-----AIDIGYRHIXCAFVYGNEKEVGEAIKTKI 306
+G ++ +G+GTW + G++T + + A D G A VY K + I
Sbjct: 45 SGLRVSCLGLGTWVTFGGQITDEMAEQLMTLAYDNGINLFDTAEVYAAGK-AEVVLGNII 103
Query: 307 QEGVVKREDLFITSKL-W-------NTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWP 456
++ +R L IT+K+ W R ++ G L+ SL L ++Y+D+ + P
Sbjct: 104 KKKGWRRSSLVITTKIFWGGKAETERGLSRKHIIEG-LKASLERLQLEYVDVVFANRP 160
>BC126424-1|AAI26425.1| 367|Homo sapiens potassium voltage-gated
channel, shaker-related subfamily, beta member 2
protein.
Length = 367
Score = 34.3 bits (75), Expect = 1.3
Identities = 30/118 (25%), Positives = 54/118 (45%), Gaps = 13/118 (11%)
Frame = +1
Query: 142 NGAKIPVIGIGTWKSKPGEVTQAVKD-----AIDIGYRHIXCAFVYGNEKEVGEAIKTKI 306
+G ++ +G+GTW + G++T + + A D G A VY K + I
Sbjct: 45 SGLRVSCLGLGTWVTFGGQITDEMAEQLMTLAYDNGINLFDTAEVYAAGK-AEVVLGNII 103
Query: 307 QEGVVKREDLFITSKL-W-------NTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWP 456
++ +R L IT+K+ W R ++ G L+ SL L ++Y+D+ + P
Sbjct: 104 KKKGWRRSSLVITTKIFWGGKAETERGLSRKHIIEG-LKASLERLQLEYVDVVFANRP 160
>BC110351-1|AAI10352.1| 395|Homo sapiens KCNAB2 protein protein.
Length = 395
Score = 34.3 bits (75), Expect = 1.3
Identities = 30/118 (25%), Positives = 54/118 (45%), Gaps = 13/118 (11%)
Frame = +1
Query: 142 NGAKIPVIGIGTWKSKPGEVTQAVKD-----AIDIGYRHIXCAFVYGNEKEVGEAIKTKI 306
+G ++ +G+GTW + G++T + + A D G A VY K + I
Sbjct: 45 SGLRVSCLGLGTWVTFGGQITDEMAEQLMTLAYDNGINLFDTAEVYAAGK-AEVVLGNII 103
Query: 307 QEGVVKREDLFITSKL-W-------NTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWP 456
++ +R L IT+K+ W R ++ G L+ SL L ++Y+D+ + P
Sbjct: 104 KKKGWRRSSLVITTKIFWGGKAETERGLSRKHIIEG-LKASLERLQLEYVDVVFANRP 160
>AL035406-6|CAI19886.1| 253|Homo sapiens potassium voltage-gated
channel, shaker-related subfamily, beta member 2
protein.
Length = 253
Score = 34.3 bits (75), Expect = 1.3
Identities = 30/118 (25%), Positives = 54/118 (45%), Gaps = 13/118 (11%)
Frame = +1
Query: 142 NGAKIPVIGIGTWKSKPGEVTQAVKD-----AIDIGYRHIXCAFVYGNEKEVGEAIKTKI 306
+G ++ +G+GTW + G++T + + A D G A VY K + I
Sbjct: 45 SGLRVSCLGLGTWVTFGGQITDEMAEQLMTLAYDNGINLFDTAEVYAAGK-AEVVLGNII 103
Query: 307 QEGVVKREDLFITSKL-W-------NTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWP 456
++ +R L IT+K+ W R ++ G L+ SL L ++Y+D+ + P
Sbjct: 104 KKKGWRRSSLVITTKIFWGGKAETERGLSRKHIIEG-LKASLERLQLEYVDVVFANRP 160
>AL035406-5|CAI19887.1| 254|Homo sapiens potassium voltage-gated
channel, shaker-related subfamily, beta member 2
protein.
Length = 254
Score = 34.3 bits (75), Expect = 1.3
Identities = 30/118 (25%), Positives = 54/118 (45%), Gaps = 13/118 (11%)
Frame = +1
Query: 142 NGAKIPVIGIGTWKSKPGEVTQAVKD-----AIDIGYRHIXCAFVYGNEKEVGEAIKTKI 306
+G ++ +G+GTW + G++T + + A D G A VY K + I
Sbjct: 31 SGLRVSCLGLGTWVTFGGQITDEMAEQLMTLAYDNGINLFDTAEVYAAGK-AEVVLGNII 89
Query: 307 QEGVVKREDLFITSKL-W-------NTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWP 456
++ +R L IT+K+ W R ++ G L+ SL L ++Y+D+ + P
Sbjct: 90 KKKGWRRSSLVITTKIFWGGKAETERGLSRKHIIEG-LKASLERLQLEYVDVVFANRP 146
>AL035406-4|CAC08512.1| 367|Homo sapiens potassium voltage-gated
channel, shaker-related subfamily, beta member 2
protein.
Length = 367
Score = 34.3 bits (75), Expect = 1.3
Identities = 30/118 (25%), Positives = 54/118 (45%), Gaps = 13/118 (11%)
Frame = +1
Query: 142 NGAKIPVIGIGTWKSKPGEVTQAVKD-----AIDIGYRHIXCAFVYGNEKEVGEAIKTKI 306
+G ++ +G+GTW + G++T + + A D G A VY K + I
Sbjct: 45 SGLRVSCLGLGTWVTFGGQITDEMAEQLMTLAYDNGINLFDTAEVYAAGK-AEVVLGNII 103
Query: 307 QEGVVKREDLFITSKL-W-------NTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWP 456
++ +R L IT+K+ W R ++ G L+ SL L ++Y+D+ + P
Sbjct: 104 KKKGWRRSSLVITTKIFWGGKAETERGLSRKHIIEG-LKASLERLQLEYVDVVFANRP 160
>AL035406-3|CAI19885.1| 353|Homo sapiens potassium voltage-gated
channel, shaker-related subfamily, beta member 2
protein.
Length = 353
Score = 34.3 bits (75), Expect = 1.3
Identities = 30/118 (25%), Positives = 54/118 (45%), Gaps = 13/118 (11%)
Frame = +1
Query: 142 NGAKIPVIGIGTWKSKPGEVTQAVKD-----AIDIGYRHIXCAFVYGNEKEVGEAIKTKI 306
+G ++ +G+GTW + G++T + + A D G A VY K + I
Sbjct: 31 SGLRVSCLGLGTWVTFGGQITDEMAEQLMTLAYDNGINLFDTAEVYAAGK-AEVVLGNII 89
Query: 307 QEGVVKREDLFITSKL-W-------NTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWP 456
++ +R L IT+K+ W R ++ G L+ SL L ++Y+D+ + P
Sbjct: 90 KKKGWRRSSLVITTKIFWGGKAETERGLSRKHIIEG-LKASLERLQLEYVDVVFANRP 146
>AK075032-1|BAC11364.1| 524|Homo sapiens protein ( Homo sapiens
cDNA FLJ90551 fis, clone OVARC1000779, weakly similar to
ZINC FINGER PROTEIN 157. ).
Length = 524
Score = 34.3 bits (75), Expect = 1.3
Identities = 19/42 (45%), Positives = 22/42 (52%)
Frame = +3
Query: 534 GHVEGSRASRVPRARPQPRCLELQLEAAPEDTRQRLCETRSL 659
GH + +RA R R PQP C EL L + P ETRSL
Sbjct: 425 GHRQ-ARAQRAGRGAPQPLCRELPLSSRPSSQGHGGSETRSL 465
>AF044253-1|AAB99859.1| 353|Homo sapiens potassium channel beta 2
subunit protein.
Length = 353
Score = 34.3 bits (75), Expect = 1.3
Identities = 30/118 (25%), Positives = 54/118 (45%), Gaps = 13/118 (11%)
Frame = +1
Query: 142 NGAKIPVIGIGTWKSKPGEVTQAVKD-----AIDIGYRHIXCAFVYGNEKEVGEAIKTKI 306
+G ++ +G+GTW + G++T + + A D G A VY K + I
Sbjct: 31 SGLRVSCLGLGTWVTFGGQITDEMAEQLMTLAYDNGINLFDTAEVYAAGK-AEVVLGNII 89
Query: 307 QEGVVKREDLFITSKL-W-------NTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWP 456
++ +R L IT+K+ W R ++ G L+ SL L ++Y+D+ + P
Sbjct: 90 KKKGWRRSSLVITTKIFWGGKAETERGLSRKHIIEG-LKASLERLQLEYVDVVFANRP 146
>AF029749-1|AAB84170.1| 367|Homo sapiens potassium channel beta 2
subunit protein.
Length = 367
Score = 34.3 bits (75), Expect = 1.3
Identities = 30/118 (25%), Positives = 54/118 (45%), Gaps = 13/118 (11%)
Frame = +1
Query: 142 NGAKIPVIGIGTWKSKPGEVTQAVKD-----AIDIGYRHIXCAFVYGNEKEVGEAIKTKI 306
+G ++ +G+GTW + G++T + + A D G A VY K + I
Sbjct: 45 SGLRVSCLGLGTWVTFGGQITDEMAEQLMTLAYDNGINLFDTAEVYAAGK-AEVVLGNII 103
Query: 307 QEGVVKREDLFITSKL-W-------NTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWP 456
++ +R L IT+K+ W R ++ G L+ SL L ++Y+D+ + P
Sbjct: 104 KKKGWRRSSLVITTKIFWGGKAETERGLSRKHIIEG-LKASLERLQLEYVDVVFANRP 160
>U72619-1|AAB61992.1| 22|Homo sapiens aldose reductase protein.
Length = 22
Score = 33.9 bits (74), Expect = 1.7
Identities = 11/16 (68%), Positives = 16/16 (100%)
Frame = +1
Query: 136 LSNGAKIPVIGIGTWK 183
L+NGAK+P++G+GTWK
Sbjct: 7 LNNGAKMPILGLGTWK 22
>X83127-1|CAA58208.1| 401|Homo sapiens voltage gated potassium
channels, beta subunit protein.
Length = 401
Score = 33.5 bits (73), Expect = 2.2
Identities = 28/119 (23%), Positives = 57/119 (47%), Gaps = 12/119 (10%)
Frame = +1
Query: 142 NGAKIPVIGIGTWKSKPGEVTQAVKDAI-DIGYRHIXCAFVYGNEKEVGEA---IKTKIQ 309
+G ++ +G+GTW + G+++ V + + I Y F G+A + + I+
Sbjct: 79 SGLRVSCLGLGTWVTFGGQISDEVAERLMTIAYESGVNLFDTAEVYAAGKAEVILGSIIK 138
Query: 310 EGVVKREDLFITSKLW--------NTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQA 462
+ +R L IT+KL+ R ++ G L+ SL+ L ++Y+D+ + P +
Sbjct: 139 KKGWRRSSLVITTKLYWGGKAETERGLSRKHIIEG-LKGSLQRLQLEYVDVVFANRPDS 196
>U33428-1|AAC50953.1| 401|Homo sapiens K+ channel beta 1a subunit
protein.
Length = 401
Score = 33.5 bits (73), Expect = 2.2
Identities = 28/119 (23%), Positives = 57/119 (47%), Gaps = 12/119 (10%)
Frame = +1
Query: 142 NGAKIPVIGIGTWKSKPGEVTQAVKDAI-DIGYRHIXCAFVYGNEKEVGEA---IKTKIQ 309
+G ++ +G+GTW + G+++ V + + I Y F G+A + + I+
Sbjct: 79 SGLRVSCLGLGTWVTFGGQISDEVAERLMTIAYESGVNLFDTAEVYAAGKAEVILGSIIK 138
Query: 310 EGVVKREDLFITSKLW--------NTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQA 462
+ +R L IT+KL+ R ++ G L+ SL+ L ++Y+D+ + P +
Sbjct: 139 KKGWRRSSLVITTKLYWGGKAETERGLSRKHIIEG-LKGSLQRLQLEYVDVVFANRPDS 196
>U16953-1|AAC50122.1| 408|Homo sapiens potassium channel beta3
subunit protein.
Length = 408
Score = 33.5 bits (73), Expect = 2.2
Identities = 28/119 (23%), Positives = 57/119 (47%), Gaps = 12/119 (10%)
Frame = +1
Query: 142 NGAKIPVIGIGTWKSKPGEVTQAVKDAI-DIGYRHIXCAFVYGNEKEVGEA---IKTKIQ 309
+G ++ +G+GTW + G+++ V + + I Y F G+A + + I+
Sbjct: 86 SGLRVSCLGLGTWVTFGGQISDEVAERLMTIAYESGVNLFDTAEVYAAGKAEVILGSIIK 145
Query: 310 EGVVKREDLFITSKLW--------NTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQA 462
+ +R L IT+KL+ R ++ G L+ SL+ L ++Y+D+ + P +
Sbjct: 146 KKGWRRSSLVITTKLYWGGKAETERGLSRKHIIEG-LKGSLQRLQLEYVDVVFANRPDS 203
>L39833-1|AAC37573.1| 408|Homo sapiens K+ channel beta-subunit
protein.
Length = 408
Score = 33.5 bits (73), Expect = 2.2
Identities = 28/119 (23%), Positives = 57/119 (47%), Gaps = 12/119 (10%)
Frame = +1
Query: 142 NGAKIPVIGIGTWKSKPGEVTQAVKDAI-DIGYRHIXCAFVYGNEKEVGEA---IKTKIQ 309
+G ++ +G+GTW + G+++ V + + I Y F G+A + + I+
Sbjct: 86 SGLRVSCLGLGTWVTFGGQISDEVAERLMTIAYESGVNLFDTAEVYAAGKAEVILGSIIK 145
Query: 310 EGVVKREDLFITSKLW--------NTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQA 462
+ +R L IT+KL+ R ++ G L+ SL+ L ++Y+D+ + P +
Sbjct: 146 KKGWRRSSLVITTKLYWGGKAETERGLSRKHIIEG-LKGSLQRLQLEYVDVVFANRPDS 203
>BC043166-1|AAH43166.1| 401|Homo sapiens potassium voltage-gated
channel, shaker-related subfamily, beta member 1
protein.
Length = 401
Score = 33.5 bits (73), Expect = 2.2
Identities = 28/119 (23%), Positives = 57/119 (47%), Gaps = 12/119 (10%)
Frame = +1
Query: 142 NGAKIPVIGIGTWKSKPGEVTQAVKDAI-DIGYRHIXCAFVYGNEKEVGEA---IKTKIQ 309
+G ++ +G+GTW + G+++ V + + I Y F G+A + + I+
Sbjct: 79 SGLRVSCLGLGTWVTFGGQISDEVAERLMTIAYESGVNLFDTAEVYAAGKAEVILGSIIK 138
Query: 310 EGVVKREDLFITSKLW--------NTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQA 462
+ +R L IT+KL+ R ++ G L+ SL+ L ++Y+D+ + P +
Sbjct: 139 KKGWRRSSLVITTKLYWGGKAETERGLSRKHIIEG-LKGSLQRLQLEYVDVVFANRPDS 196
>AF026947-1|AAC52104.1| 330|Homo sapiens aflatoxin aldehyde
reductase AFAR protein.
Length = 330
Score = 32.3 bits (70), Expect = 5.0
Identities = 23/86 (26%), Positives = 41/86 (47%), Gaps = 3/86 (3%)
Frame = +1
Query: 208 AVKDAIDIGYRHIXCAFVY--GNEKEVGEAIKTKIQEGVVKREDLFITSKLWNTFH-RPD 378
AV+ ++ G+ + AF+Y G + + + + G R + + W+ +PD
Sbjct: 30 AVRAFLERGHTELDTAFMYSDGQSETILGGLGLGLGGGDC-RVKIATKANPWDGKSLKPD 88
Query: 379 LVRGALEVSLRNLNIDYLDLYLIHWP 456
VR LE SL+ L +DL+ +H P
Sbjct: 89 SVRSQLETSLKRLQCPQVDLFYLHTP 114
>Y16675-1|CAA76347.1| 330|Homo sapiens aflatoxin B1-aldehyde
reductase protein.
Length = 330
Score = 31.9 bits (69), Expect = 6.7
Identities = 23/86 (26%), Positives = 41/86 (47%), Gaps = 3/86 (3%)
Frame = +1
Query: 208 AVKDAIDIGYRHIXCAFVY--GNEKEVGEAIKTKIQEGVVKREDLFITSKLWNTFH-RPD 378
AV+ ++ G+ + AF+Y G + + + + G R + + W+ +PD
Sbjct: 30 AVRAFLERGHTELDTAFMYSDGQSETILGGLGLGLGGGDC-RVKIATKANPWDGKSLKPD 88
Query: 379 LVRGALEVSLRNLNIDYLDLYLIHWP 456
VR LE SL+ L +DL+ +H P
Sbjct: 89 SVRSQLETSLKRLQCPQVDLFYLHAP 114
>CR542264-1|CAG47060.1| 353|Homo sapiens KCNAB2 protein.
Length = 353
Score = 31.9 bits (69), Expect = 6.7
Identities = 29/118 (24%), Positives = 53/118 (44%), Gaps = 13/118 (11%)
Frame = +1
Query: 142 NGAKIPVIGIGTWKSKPGEVTQAVKD-----AIDIGYRHIXCAFVYGNEKEVGEAIKTKI 306
+G ++ +G+GTW + G++T + + A D G A VY K + I
Sbjct: 31 SGLRVSCLGLGTWVTFGGQITDEMAEQLMTLAYDNGINLFDTAEVYAAGK-AEVVLGNII 89
Query: 307 QEGVVKREDLFITSKL-W-------NTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWP 456
++ +R L IT+K+ W R ++ G L+ SL ++Y+D+ + P
Sbjct: 90 KKKGWRRSSLVITTKIFWGGKAETERGLSRKHIIEG-LKASLERRQLEYVDVVFANRP 146
>BT007347-1|AAP36011.1| 330|Homo sapiens aldo-keto reductase family
7, member A2 (aflatoxin aldehyde reductase) protein.
Length = 330
Score = 31.9 bits (69), Expect = 6.7
Identities = 23/86 (26%), Positives = 41/86 (47%), Gaps = 3/86 (3%)
Frame = +1
Query: 208 AVKDAIDIGYRHIXCAFVY--GNEKEVGEAIKTKIQEGVVKREDLFITSKLWNTFH-RPD 378
AV+ ++ G+ + AF+Y G + + + + G R + + W+ +PD
Sbjct: 30 AVRAFLERGHTELDTAFMYSDGQSETILGGLGLGLGGGDC-RVKIATKANPWDGKSLKPD 88
Query: 379 LVRGALEVSLRNLNIDYLDLYLIHWP 456
VR LE SL+ L +DL+ +H P
Sbjct: 89 SVRSQLETSLKRLQCPQVDLFYLHAP 114
>BC013996-1|AAH13996.1| 330|Homo sapiens AKR7A2 protein protein.
Length = 330
Score = 31.9 bits (69), Expect = 6.7
Identities = 23/86 (26%), Positives = 41/86 (47%), Gaps = 3/86 (3%)
Frame = +1
Query: 208 AVKDAIDIGYRHIXCAFVY--GNEKEVGEAIKTKIQEGVVKREDLFITSKLWNTFH-RPD 378
AV+ ++ G+ + AF+Y G + + + + G R + + W+ +PD
Sbjct: 30 AVRAFLERGHTELDTAFMYSDGQSETILGGLGLGLGGGDC-RVKIATKANPWDGKSLKPD 88
Query: 379 LVRGALEVSLRNLNIDYLDLYLIHWP 456
VR LE SL+ L +DL+ +H P
Sbjct: 89 SVRSQLETSLKRLQCPQVDLFYLHAP 114
>BC012171-1|AAH12171.1| 330|Homo sapiens AKR7A2 protein protein.
Length = 330
Score = 31.9 bits (69), Expect = 6.7
Identities = 23/86 (26%), Positives = 41/86 (47%), Gaps = 3/86 (3%)
Frame = +1
Query: 208 AVKDAIDIGYRHIXCAFVY--GNEKEVGEAIKTKIQEGVVKREDLFITSKLWNTFH-RPD 378
AV+ ++ G+ + AF+Y G + + + + G R + + W+ +PD
Sbjct: 30 AVRAFLERGHTELDTAFMYSDGQSETILGGLGLGLGGGDC-RVKIATKANPWDGKSLKPD 88
Query: 379 LVRGALEVSLRNLNIDYLDLYLIHWP 456
VR LE SL+ L +DL+ +H P
Sbjct: 89 SVRSQLETSLKRLQCPQVDLFYLHAP 114
>BC011586-1|AAH11586.1| 330|Homo sapiens AKR7A2 protein protein.
Length = 330
Score = 31.9 bits (69), Expect = 6.7
Identities = 23/86 (26%), Positives = 41/86 (47%), Gaps = 3/86 (3%)
Frame = +1
Query: 208 AVKDAIDIGYRHIXCAFVY--GNEKEVGEAIKTKIQEGVVKREDLFITSKLWNTFH-RPD 378
AV+ ++ G+ + AF+Y G + + + + G R + + W+ +PD
Sbjct: 30 AVRAFLERGHTELDTAFMYSDGQSETILGGLGLGLGGGDC-RVKIATKANPWDGKSLKPD 88
Query: 379 LVRGALEVSLRNLNIDYLDLYLIHWP 456
VR LE SL+ L +DL+ +H P
Sbjct: 89 SVRSQLETSLKRLQCPQVDLFYLHAP 114
>BC010852-1|AAH10852.1| 330|Homo sapiens AKR7A2 protein protein.
Length = 330
Score = 31.9 bits (69), Expect = 6.7
Identities = 23/86 (26%), Positives = 41/86 (47%), Gaps = 3/86 (3%)
Frame = +1
Query: 208 AVKDAIDIGYRHIXCAFVY--GNEKEVGEAIKTKIQEGVVKREDLFITSKLWNTFH-RPD 378
AV+ ++ G+ + AF+Y G + + + + G R + + W+ +PD
Sbjct: 30 AVRAFLERGHTELDTAFMYSDGQSETILGGLGLGLGGGDC-RVKIATKANPWDGKSLKPD 88
Query: 379 LVRGALEVSLRNLNIDYLDLYLIHWP 456
VR LE SL+ L +DL+ +H P
Sbjct: 89 SVRSQLETSLKRLQCPQVDLFYLHAP 114
>BC007352-1|AAH07352.2| 358|Homo sapiens AKR7A2 protein protein.
Length = 358
Score = 31.9 bits (69), Expect = 6.7
Identities = 23/86 (26%), Positives = 41/86 (47%), Gaps = 3/86 (3%)
Frame = +1
Query: 208 AVKDAIDIGYRHIXCAFVY--GNEKEVGEAIKTKIQEGVVKREDLFITSKLWNTFH-RPD 378
AV+ ++ G+ + AF+Y G + + + + G R + + W+ +PD
Sbjct: 58 AVRAFLERGHTELDTAFMYSDGQSETILGGLGLGLGGGDC-RVKIATKANPWDGKSLKPD 116
Query: 379 LVRGALEVSLRNLNIDYLDLYLIHWP 456
VR LE SL+ L +DL+ +H P
Sbjct: 117 SVRSQLETSLKRLQCPQVDLFYLHAP 142
>BC004111-1|AAH04111.3| 330|Homo sapiens AKR7A2 protein protein.
Length = 330
Score = 31.9 bits (69), Expect = 6.7
Identities = 23/86 (26%), Positives = 41/86 (47%), Gaps = 3/86 (3%)
Frame = +1
Query: 208 AVKDAIDIGYRHIXCAFVY--GNEKEVGEAIKTKIQEGVVKREDLFITSKLWNTFH-RPD 378
AV+ ++ G+ + AF+Y G + + + + G R + + W+ +PD
Sbjct: 30 AVRAFLERGHTELDTAFMYSDGQSETILGGLGLGLGGGDC-RVKIATKANPWDGKSLKPD 88
Query: 379 LVRGALEVSLRNLNIDYLDLYLIHWP 456
VR LE SL+ L +DL+ +H P
Sbjct: 89 SVRSQLETSLKRLQCPQVDLFYLHAP 114
>AL035413-8|CAB72321.1| 330|Homo sapiens aldo-keto reductase family
7, member A2 (aflatoxin aldehyde reductase) protein.
Length = 330
Score = 31.9 bits (69), Expect = 6.7
Identities = 23/86 (26%), Positives = 41/86 (47%), Gaps = 3/86 (3%)
Frame = +1
Query: 208 AVKDAIDIGYRHIXCAFVY--GNEKEVGEAIKTKIQEGVVKREDLFITSKLWNTFH-RPD 378
AV+ ++ G+ + AF+Y G + + + + G R + + W+ +PD
Sbjct: 30 AVRAFLERGHTELDTAFMYSDGQSETILGGLGLGLGGGDC-RVKIATKANPWDGKSLKPD 88
Query: 379 LVRGALEVSLRNLNIDYLDLYLIHWP 456
VR LE SL+ L +DL+ +H P
Sbjct: 89 SVRSQLETSLKRLQCPQVDLFYLHAP 114
>AJ278012-1|CAC79668.1| 259|Homo sapiens aflatoxin B1 aldehyde
reductase 3 protein.
Length = 259
Score = 31.5 bits (68), Expect = 8.8
Identities = 13/29 (44%), Positives = 18/29 (62%)
Frame = +1
Query: 370 RPDLVRGALEVSLRNLNIDYLDLYLIHWP 456
+PD VR LE SL+ L +DL+ +H P
Sbjct: 15 KPDSVRSQLETSLKRLQCPUVDLFYLHAP 43
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 155,873,188
Number of Sequences: 237096
Number of extensions: 2910837
Number of successful extensions: 6696
Number of sequences better than 10.0: 125
Number of HSP's better than 10.0 without gapping: 6145
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 6669
length of database: 76,859,062
effective HSP length: 94
effective length of database: 54,572,038
effective search space used: 23738836530
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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