SilkBase IMG001 IMG002 IMG003 IMG005 IMG006 IMG007 IMG008 IMG009 kuwako IMG010 IMG011 IMG012

Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= 030731E7_B08_e634_04.seq
         (1525 letters)

Database: uniref50 
           1,657,284 sequences; 575,637,011 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

UniRef50_Q5BLA6 Cluster: Zgc:110782; n=2; Danio rerio|Rep: Zgc:1...   138   3e-31
UniRef50_Q5XJM7 Cluster: Zgc:101765; n=5; Eumetazoa|Rep: Zgc:101...   136   1e-30
UniRef50_UPI00015B5BD7 Cluster: PREDICTED: similar to aldo-keto ...   130   7e-29
UniRef50_UPI0000DB6EE9 Cluster: PREDICTED: similar to C35D10.6; ...   124   6e-27
UniRef50_Q5TNP1 Cluster: ENSANGP00000029046; n=2; Culicidae|Rep:...   117   7e-25
UniRef50_Q6WGK4 Cluster: Aldose reductase; n=1; Pristionchus pac...   115   4e-24
UniRef50_Q1U9L6 Cluster: 2,5-didehydrogluconate reductase; n=3; ...   113   1e-23
UniRef50_P70883 Cluster: AkrI; n=1; Butyrivibrio fibrisolvens|Re...   110   1e-22
UniRef50_Q54NR2 Cluster: Aldo-keto reductase; n=3; Dictyostelium...   108   3e-22
UniRef50_Q21274 Cluster: Putative uncharacterized protein; n=1; ...   108   4e-22
UniRef50_Q18483 Cluster: Putative uncharacterized protein; n=2; ...   108   4e-22
UniRef50_Q17568 Cluster: Putative uncharacterized protein; n=1; ...   107   6e-22
UniRef50_P91997 Cluster: Putative uncharacterized protein; n=4; ...   106   1e-21
UniRef50_A6NPD6 Cluster: Putative uncharacterized protein; n=3; ...   104   5e-21
UniRef50_A6ESC0 Cluster: ARA1; n=1; unidentified eubacterium SCB...   103   9e-21
UniRef50_Q88SL1 Cluster: Oxidoreductase; n=51; Lactobacillales|R...   101   4e-20
UniRef50_Q5FLI5 Cluster: Aldehyde reductase; n=2; Bacteria|Rep: ...    99   2e-19
UniRef50_Q8F1G4 Cluster: Aldehyde reductase; n=8; Bacteria|Rep: ...   100   2e-19
UniRef50_Q838E0 Cluster: Oxidoreductase, aldo/keto reductase fam...    99   3e-19
UniRef50_Q23320 Cluster: Putative uncharacterized protein; n=4; ...    98   6e-19
UniRef50_Q9X0A2 Cluster: Oxidoreductase, aldo/keto reductase fam...    96   2e-18
UniRef50_Q05KR9 Cluster: Benzil reductase; n=5; Bacillales|Rep: ...    96   2e-18
UniRef50_Q5HR31 Cluster: Oxidoreductase, aldo/keto reductase fam...    94   8e-18
UniRef50_Q2V420 Cluster: Uncharacterized protein At2g37770.1; n=...    93   2e-17
UniRef50_Q0PGJ6 Cluster: Aldo-keto reductase; n=32; Magnoliophyt...    93   2e-17
UniRef50_P45376 Cluster: Aldose reductase; n=21; Bilateria|Rep: ...    93   2e-17
UniRef50_P15121 Cluster: Aldose reductase; n=72; Eumetazoa|Rep: ...    92   4e-17
UniRef50_Q03TW0 Cluster: Aldo/keto reductase of diketogulonate r...    91   7e-17
UniRef50_Q8CI22 Cluster: 2310005E10Rik protein; n=30; Tetrapoda|...    91   9e-17
UniRef50_Q41E86 Cluster: 2,5-didehydrogluconate reductase; n=2; ...    91   9e-17
UniRef50_Q9VHX4 Cluster: CG2767-PA; n=4; Endopterygota|Rep: CG27...    91   9e-17
UniRef50_Q03PG5 Cluster: Aldo/keto reductase of diketogulonate r...    90   2e-16
UniRef50_Q16K66 Cluster: Aldo-keto reductase; n=2; Aedes aegypti...    90   2e-16
UniRef50_Q5FK98 Cluster: Oxidoreductase; n=8; Lactobacillales|Re...    89   2e-16
UniRef50_A2UAH0 Cluster: Aldo/keto reductase; n=1; Bacillus coag...    89   2e-16
UniRef50_A6LZ55 Cluster: 2,5-didehydrogluconate reductase; n=1; ...    89   4e-16
UniRef50_Q09632 Cluster: Probable oxidoreductase ZK1290.5; n=2; ...    89   4e-16
UniRef50_Q03XK0 Cluster: Aldo/keto reductase of diketogulonate r...    88   5e-16
UniRef50_Q7NB44 Cluster: ARA1; n=3; Firmicutes|Rep: ARA1 - Mycop...    88   7e-16
UniRef50_Q61U89 Cluster: Putative uncharacterized protein CBG054...    88   7e-16
UniRef50_A0JRJ6 Cluster: Aldo/keto reductase; n=2; Micrococcinea...    87   9e-16
UniRef50_Q24C22 Cluster: Oxidoreductase, aldo/keto reductase fam...    87   9e-16
UniRef50_P38715 Cluster: NADPH-dependent aldose reductase GRE3; ...    87   1e-15
UniRef50_Q2LZ66 Cluster: GA19341-PA; n=2; Endopterygota|Rep: GA1...    86   2e-15
UniRef50_Q22352 Cluster: Putative uncharacterized protein T08H10...    86   2e-15
UniRef50_UPI0000588153 Cluster: PREDICTED: hypothetical protein;...    86   3e-15
UniRef50_UPI000065D0BD Cluster: Homolog of Homo sapiens "AKR1B1 ...    86   3e-15
UniRef50_P22045 Cluster: Probable reductase; n=101; cellular org...    86   3e-15
UniRef50_Q02198 Cluster: Morphine 6-dehydrogenase; n=5; Bacteria...    86   3e-15
UniRef50_Q55FL3 Cluster: Aldo-keto reductase; n=2; Dictyostelium...    85   5e-15
UniRef50_Q7VG53 Cluster: Aldo-keto reductase; n=28; Bacteria|Rep...    85   6e-15
UniRef50_P38115 Cluster: D-arabinose dehydrogenase [NAD(P)+] hea...    85   6e-15
UniRef50_Q8WRT0 Cluster: 3-dehydrecdysone 3b-reductase; n=1; Tri...    84   8e-15
UniRef50_Q54B70 Cluster: Aldehyde reductase; n=2; Dictyostelium ...    84   8e-15
UniRef50_Q9VTL0 Cluster: CG6083-PA; n=4; Diptera|Rep: CG6083-PA ...    84   1e-14
UniRef50_A5E082 Cluster: GCY protein; n=4; Saccharomycetales|Rep...    84   1e-14
UniRef50_A3LTU8 Cluster: D-arabinose dehydrogenase; n=5; Sacchar...    84   1e-14
UniRef50_UPI00006CA3CB Cluster: oxidoreductase, aldo/keto reduct...    83   1e-14
UniRef50_Q568D7 Cluster: Zgc:110366; n=7; Euteleostomi|Rep: Zgc:...    83   1e-14
UniRef50_A3JU52 Cluster: 2,5-diketo-D-gluconic acid reductase A;...    83   1e-14
UniRef50_Q2UGR1 Cluster: Aldo/keto reductase family proteins; n=...    83   1e-14
UniRef50_A7PNI3 Cluster: Chromosome chr1 scaffold_22, whole geno...    83   2e-14
UniRef50_Q0IBY6 Cluster: Alcohol dehydrogenase; n=2; Chroococcal...    82   3e-14
UniRef50_Q6TY50 Cluster: Reductase 2; n=10; Magnoliophyta|Rep: R...    82   3e-14
UniRef50_Q7PM68 Cluster: ENSANGP00000014386; n=1; Anopheles gamb...    82   3e-14
UniRef50_Q8SSK6 Cluster: ALDOSE REDUCTASE; n=1; Encephalitozoon ...    82   4e-14
UniRef50_Q6NII7 Cluster: Putative oxidoreductase; n=2; Corynebac...    81   6e-14
UniRef50_Q1RFP0 Cluster: 2,5-diketo-D-gluconic acid reductase A;...    81   6e-14
UniRef50_Q9ZBW7 Cluster: Putative oxidoreductase; n=2; Actinomyc...    81   8e-14
UniRef50_Q927E1 Cluster: Lin2848 protein; n=13; Listeria|Rep: Li...    81   8e-14
UniRef50_A5KSS3 Cluster: Aldehyde reductase; n=1; candidate divi...    81   8e-14
UniRef50_Q7ZA52 Cluster: Aldose reductase; n=6; Pezizomycotina|R...    81   8e-14
UniRef50_A6RKL9 Cluster: Putative uncharacterized protein; n=3; ...    81   8e-14
UniRef50_A7CWF9 Cluster: Aldehyde reductase; n=2; Bacteria|Rep: ...    81   1e-13
UniRef50_A4FEB9 Cluster: 2,5-diketo-D-gluconic acid reductase; n...    81   1e-13
UniRef50_A1D4E3 Cluster: D-xylose reductase (Xyl1), putative; n=...    81   1e-13
UniRef50_Q235V6 Cluster: Oxidoreductase, aldo/keto reductase fam...    80   1e-13
UniRef50_Q4P4P1 Cluster: Putative uncharacterized protein; n=1; ...    80   1e-13
UniRef50_Q890A0 Cluster: Oxidoreductase; n=6; Lactobacillales|Re...    80   2e-13
UniRef50_Q7JVH6 Cluster: LD24696p; n=2; Sophophora|Rep: LD24696p...    80   2e-13
UniRef50_Q4PE96 Cluster: Putative uncharacterized protein; n=1; ...    80   2e-13
UniRef50_Q8EVT8 Cluster: Oxidoreductase-aldo/keto reductase fami...    79   2e-13
UniRef50_UPI00015B56A2 Cluster: PREDICTED: similar to GA10458-PA...    79   3e-13
UniRef50_UPI00006CCCD7 Cluster: oxidoreductase, aldo/keto reduct...    79   3e-13
UniRef50_UPI0000498F1F Cluster: oxidoreductase, aldo/keto reduct...    79   3e-13
UniRef50_Q2S340 Cluster: Aldehyde reductase; n=10; Bacteria|Rep:...    79   3e-13
UniRef50_Q1VRG6 Cluster: YvgN; n=1; Psychroflexus torquis ATCC 7...    79   3e-13
UniRef50_A0JX62 Cluster: 2,5-didehydrogluconate reductase; n=9; ...    79   3e-13
UniRef50_A2R6Z3 Cluster: Catalytic activity: an alcohol + NADP(+...    79   3e-13
UniRef50_P47137 Cluster: Probable oxidoreductase YJR096W; n=8; S...    79   3e-13
UniRef50_UPI00006CD296 Cluster: oxidoreductase, aldo/keto reduct...    79   4e-13
UniRef50_A4RQH8 Cluster: Predicted protein; n=2; Ostreococcus|Re...    79   4e-13
UniRef50_Q968S3 Cluster: Aldoketoreductase-like protein; n=1; Or...    79   4e-13
UniRef50_Q9C1X5 Cluster: Xylose and arabinose reductase; n=1; Sc...    79   4e-13
UniRef50_Q7VHE1 Cluster: Putative uncharacterized protein; n=1; ...    78   5e-13
UniRef50_Q4Q5N9 Cluster: Prostaglandin f synthase, putative; n=7...    78   7e-13
UniRef50_Q17G72 Cluster: Aldo-keto reductase; n=9; Endopterygota...    78   7e-13
UniRef50_UPI0000519CC2 Cluster: PREDICTED: similar to CG2767-PA;...    77   9e-13
UniRef50_Q8Y463 Cluster: Lmo2592 protein; n=40; Bacteria|Rep: Lm...    77   9e-13
UniRef50_Q4PDR0 Cluster: Putative uncharacterized protein; n=1; ...    77   1e-12
UniRef50_Q88TV9 Cluster: Oxidoreductase; n=4; Lactobacillus|Rep:...    77   2e-12
UniRef50_A6VNW9 Cluster: Aldo/keto reductase precursor; n=1; Act...    76   2e-12
UniRef50_Q10494 Cluster: Probable oxidoreductase C26F1.07; n=2; ...    76   2e-12
UniRef50_A7ALH6 Cluster: Putative uncharacterized protein; n=1; ...    76   3e-12
UniRef50_A2QBD7 Cluster: Catalytic activity: an alcohol + NADP(+...    76   3e-12
UniRef50_UPI00015B56A3 Cluster: PREDICTED: similar to aldo-keto ...    75   4e-12
UniRef50_Q1IN88 Cluster: Aldehyde reductase; n=5; Bacteria|Rep: ...    75   4e-12
UniRef50_Q9Y020 Cluster: 3-dehydroecdysone 3beta-reductase precu...    75   4e-12
UniRef50_A2QVE5 Cluster: Similarity: shows similarity to several...    75   4e-12
UniRef50_P14550 Cluster: Alcohol dehydrogenase [NADP+]; n=44; Bi...    75   4e-12
UniRef50_Q96UH3 Cluster: Aldehyde reductase; n=13; Pezizomycotin...    75   5e-12
UniRef50_Q5FKI1 Cluster: Reductase-dehydrogenase; n=1; Lactobaci...    75   7e-12
UniRef50_Q11BF8 Cluster: Aldo/keto reductase; n=12; Bacteria|Rep...    75   7e-12
UniRef50_Q03X85 Cluster: Aldo/keto reductase of diketogulonate r...    75   7e-12
UniRef50_A7SIT3 Cluster: Predicted protein; n=1; Nematostella ve...    75   7e-12
UniRef50_Q6C2L0 Cluster: Yarrowia lipolytica chromosome F of str...    74   9e-12
UniRef50_UPI00015B4B22 Cluster: PREDICTED: similar to GA15457-PA...    74   1e-11
UniRef50_Q8EUH6 Cluster: Oxidoreductase; n=1; Mycoplasma penetra...    74   1e-11
UniRef50_Q17DN0 Cluster: Aldo-keto reductase; n=5; Culicidae|Rep...    74   1e-11
UniRef50_Q929C8 Cluster: Lin2349 protein; n=12; Listeria|Rep: Li...    73   2e-11
UniRef50_Q3CZS2 Cluster: Oxidoreductase, aldo/keto reductase fam...    73   2e-11
UniRef50_Q03U37 Cluster: Aldo/keto reductase of diketogulonate r...    73   2e-11
UniRef50_Q927P9 Cluster: Lin2739 protein; n=12; Bacteria|Rep: Li...    73   2e-11
UniRef50_Q043M4 Cluster: Aldo/keto reductase of diketogulonate r...    73   2e-11
UniRef50_P27800 Cluster: Aldehyde reductase 1; n=18; root|Rep: A...    73   2e-11
UniRef50_Q14LU6 Cluster: Putative aldo/keto reductase oxidoreduc...    73   3e-11
UniRef50_Q41399 Cluster: Chalcone reductase; n=4; eudicotyledons...    73   3e-11
UniRef50_Q6CFG7 Cluster: Yarrowia lipolytica chromosome B of str...    73   3e-11
UniRef50_A4YQ04 Cluster: 2,5-diketo-D-gluconate reductase B; n=1...    72   3e-11
UniRef50_A1UEC5 Cluster: 2,5-didehydrogluconate reductase; n=20;...    72   3e-11
UniRef50_Q5KI95 Cluster: Aldo-keto reductase, putative; n=14; Di...    72   3e-11
UniRef50_UPI00015B40FA Cluster: PREDICTED: similar to CG2767-PA;...    72   5e-11
UniRef50_Q1YPE5 Cluster: Aldehyde reductase; n=7; Bacteria|Rep: ...    72   5e-11
UniRef50_A0JRJ3 Cluster: 2,5-didehydrogluconate reductase; n=3; ...    72   5e-11
UniRef50_A7RRF6 Cluster: Predicted protein; n=2; Nematostella ve...    71   6e-11
UniRef50_P28475 Cluster: NADP-dependent D-sorbitol-6-phosphate d...    71   8e-11
UniRef50_P23901 Cluster: Aldose reductase; n=9; Poaceae|Rep: Ald...    71   8e-11
UniRef50_Q5KCN9 Cluster: Putative uncharacterized protein; n=1; ...    70   1e-10
UniRef50_A2QL02 Cluster: Putative frameshift; n=1; Aspergillus n...    70   1e-10
UniRef50_UPI0000E4A7CE Cluster: PREDICTED: similar to LOC553452 ...    70   2e-10
UniRef50_UPI000023D0F1 Cluster: hypothetical protein FG03517.1; ...    70   2e-10
UniRef50_A3U9Y0 Cluster: Aldehyde reductase; n=5; Bacteroidetes|...    70   2e-10
UniRef50_Q9NAI5 Cluster: Putative uncharacterized protein; n=3; ...    70   2e-10
UniRef50_Q2BBN7 Cluster: YvgN; n=1; Bacillus sp. NRRL B-14911|Re...    69   3e-10
UniRef50_Q75E75 Cluster: ABL209Cp; n=1; Eremothecium gossypii|Re...    69   3e-10
UniRef50_A7EW94 Cluster: Putative uncharacterized protein; n=1; ...    69   4e-10
UniRef50_P06632 Cluster: 2,5-diketo-D-gluconic acid reductase A;...    69   4e-10
UniRef50_UPI0000D56CE5 Cluster: PREDICTED: similar to CG6084-PA,...    68   6e-10
UniRef50_Q0VGY1 Cluster: 3-alpha-hydroxysteroid dehydrogenase; n...    68   6e-10
UniRef50_Q9FJK0 Cluster: Aldose reductase-like protein; n=3; cor...    68   6e-10
UniRef50_Q8G7K9 Cluster: Dehydrogenase or reductase protein; n=4...    68   8e-10
UniRef50_Q7ZWA4 Cluster: Zgc:56622; n=6; cellular organisms|Rep:...    67   1e-09
UniRef50_Q7QK25 Cluster: ENSANGP00000019775; n=2; Anopheles gamb...    67   1e-09
UniRef50_Q4JX70 Cluster: Putative oxidoreductase; n=1; Corynebac...    67   1e-09
UniRef50_Q01HB5 Cluster: OSIGBa0136O08-OSIGBa0153H12.9 protein; ...    67   1e-09
UniRef50_A7SGW6 Cluster: Predicted protein; n=1; Nematostella ve...    67   1e-09
UniRef50_Q7G765 Cluster: Probable NAD(P)H-dependent oxidoreducta...    67   1e-09
UniRef50_Q5FK99 Cluster: Oxidoreductase aldo-keto reductase fami...    66   2e-09
UniRef50_Q9P6D3 Cluster: Related to aldo-keto reductase YPR1; n=...    66   2e-09
UniRef50_Q0CLQ2 Cluster: Putative uncharacterized protein; n=1; ...    66   2e-09
UniRef50_Q7N0E4 Cluster: 2,5-diketo-D-gluconic acid reductase A;...    66   2e-09
UniRef50_Q7PCV3 Cluster: ENSANGP00000031808; n=9; Endopterygota|...    66   2e-09
UniRef50_Q68ST9 Cluster: Reductase AKOR2; n=2; Pleurotus djamor|...    66   2e-09
UniRef50_Q96JD6-2 Cluster: Isoform 2 of Q96JD6 ; n=4; Catarrhini...    66   3e-09
UniRef50_Q83N50 Cluster: 2,5-diketo-D-gluconic acid reductase; n...    66   3e-09
UniRef50_Q572D2 Cluster: Aldo-keto reductase, putative; n=1; Phy...    66   3e-09
UniRef50_Q68A33 Cluster: Aldo-keto reductase 1a; n=1; Ciona inte...    66   3e-09
UniRef50_Q96JD6 Cluster: Aldo-keto reductase family 1 member C-l...    66   3e-09
UniRef50_A5VK30 Cluster: 2,5-didehydrogluconate reductase; n=2; ...    65   4e-09
UniRef50_Q7XY49 Cluster: Mannose 6-phosphate reductase; n=1; Gri...    65   4e-09
UniRef50_Q7QVQ9 Cluster: GLP_302_44328_45269; n=1; Giardia lambl...    65   4e-09
UniRef50_Q8J0K1 Cluster: 4-dihydromethyltrisporate dehydrogenase...    65   4e-09
UniRef50_A5DRJ6 Cluster: Putative uncharacterized protein; n=4; ...    65   4e-09
UniRef50_P26690 Cluster: NAD(P)H-dependent 6'-deoxychalcone synt...    65   4e-09
UniRef50_Q4WUF7 Cluster: Aldo-keto reductase, putative; n=3; Pez...    65   5e-09
UniRef50_Q5UX52 Cluster: Oxidoreductase aldo/keto reductase fami...    65   5e-09
UniRef50_A7CUW0 Cluster: 2,5-didehydrogluconate reductase; n=6; ...    64   7e-09
UniRef50_A5ZYE6 Cluster: Putative uncharacterized protein; n=1; ...    64   7e-09
UniRef50_A7RUA2 Cluster: Predicted protein; n=1; Nematostella ve...    64   7e-09
UniRef50_A2G4I3 Cluster: Oxidoreductase, aldo/keto reductase fam...    64   7e-09
UniRef50_Q9HGY0 Cluster: Glycerol dehydrogenase; n=8; Saccharomy...    64   7e-09
UniRef50_Q6CGE9 Cluster: Similar to sp|P47137 Saccharomyces cere...    64   7e-09
UniRef50_Q4DJ59 Cluster: Aldo/keto reductase, putative; n=2; Try...    64   9e-09
UniRef50_Q76L37 Cluster: Conjugated polyketone reductase C1; n=3...    64   9e-09
UniRef50_Q7G764 Cluster: Probable NAD(P)H-dependent oxidoreducta...    64   9e-09
UniRef50_P14065 Cluster: Protein GCY; n=13; Saccharomycetales|Re...    64   9e-09
UniRef50_Q6U5V3 Cluster: Putative uncharacterized protein; n=1; ...    64   1e-08
UniRef50_A7BA05 Cluster: Putative uncharacterized protein; n=1; ...    64   1e-08
UniRef50_Q4FY75 Cluster: Aldo-keto reductase-like protein; n=5; ...    64   1e-08
UniRef50_Q2U219 Cluster: Aldo/keto reductase family proteins; n=...    64   1e-08
UniRef50_O14088 Cluster: Xylose and arabinose reductase; n=1; Sc...    64   1e-08
UniRef50_Q9X265 Cluster: Oxidoreductase, aldo/keto reductase fam...    63   2e-08
UniRef50_Q6RZX1 Cluster: Gld1; n=22; Pezizomycotina|Rep: Gld1 - ...    63   2e-08
UniRef50_A3VHZ9 Cluster: Oxidoreductase; n=1; Rhodobacterales ba...    63   2e-08
UniRef50_Q00XM4 Cluster: Aldo/keto reductase family proteins; n=...    63   2e-08
UniRef50_Q8ZI40 Cluster: 2,5-diketo-D-gluconic acid reductase A;...    63   2e-08
UniRef50_UPI000155CAC7 Cluster: PREDICTED: hypothetical protein;...    62   3e-08
UniRef50_Q4Q973 Cluster: Aldo/keto reductase, putative; n=3; Lei...    62   3e-08
UniRef50_A2EHN6 Cluster: Oxidoreductase, aldo/keto reductase fam...    62   3e-08
UniRef50_Q4PAT5 Cluster: Putative uncharacterized protein; n=1; ...    62   3e-08
UniRef50_Q8EVS8 Cluster: Oxidoreductase; n=1; Mycoplasma penetra...    62   4e-08
UniRef50_A5PDA8 Cluster: Putative oxidoreductase protein; n=1; E...    62   4e-08
UniRef50_A7D6Q0 Cluster: Aldo/keto reductase; n=1; Halorubrum la...    62   4e-08
UniRef50_Q8VC28 Cluster: Aldo-keto reductase family 1 member C13...    62   4e-08
UniRef50_UPI0000E45E29 Cluster: PREDICTED: similar to aldose red...    62   5e-08
UniRef50_Q5K8C5 Cluster: Aldo-keto reductase, putative; n=1; Fil...    62   5e-08
UniRef50_Q9A2X8 Cluster: Oxidoreductase, aldo/keto reductase fam...    61   7e-08
UniRef50_Q7WSY4 Cluster: Putative aldo-keto reductase; n=1; Prop...    61   7e-08
UniRef50_Q9ZUJ6 Cluster: T2K10.1 protein; n=16; core eudicotyled...    61   7e-08
UniRef50_Q7R2T6 Cluster: GLP_291_56367_57278; n=1; Giardia lambl...    61   7e-08
UniRef50_Q5BKE9 Cluster: LOC594893 protein; n=5; Xenopus tropica...    61   9e-08
UniRef50_Q5KD52 Cluster: Oxidoreductase, putative; n=1; Filobasi...    61   9e-08
UniRef50_A3T261 Cluster: Putative uncharacterized protein; n=1; ...    60   2e-07
UniRef50_A1CAM7 Cluster: Aldo-keto reductase, putative; n=9; Dik...    60   2e-07
UniRef50_Q11B35 Cluster: Aldo/keto reductase; n=1; Mesorhizobium...    60   2e-07
UniRef50_A5AD50 Cluster: Putative uncharacterized protein; n=3; ...    60   2e-07
UniRef50_A3C1Z7 Cluster: Putative uncharacterized protein; n=2; ...    60   2e-07
UniRef50_UPI0000D9A956 Cluster: PREDICTED: similar to aldo-keto ...    59   3e-07
UniRef50_Q6F7K7 Cluster: 2,5-diketo-D-gluconate reductase; n=20;...    59   3e-07
UniRef50_Q9U2J5 Cluster: Putative uncharacterized protein; n=2; ...    59   3e-07
UniRef50_A6RMS0 Cluster: Putative uncharacterized protein; n=1; ...    59   3e-07
UniRef50_Q5UYI9 Cluster: Oxidoreductase; n=1; Haloarcula marismo...    59   3e-07
UniRef50_P51857 Cluster: 3-oxo-5-beta-steroid 4-dehydrogenase (E...    59   3e-07
UniRef50_Q8ET73 Cluster: 2,5-diketo-D-gluconate reductase; n=12;...    58   5e-07
UniRef50_Q0GU15 Cluster: ORF28; n=3; Bacteria|Rep: ORF28 - Lacto...    58   5e-07
UniRef50_Q8K023 Cluster: Aldo-keto reductase family 1 member C18...    58   5e-07
UniRef50_A3UJS6 Cluster: Oxidoreductase; n=3; Alphaproteobacteri...    58   6e-07
UniRef50_Q01J82 Cluster: OSIGBa0152K17.5 protein; n=28; Magnolio...    58   6e-07
UniRef50_P91021 Cluster: Putative uncharacterized protein; n=1; ...    58   6e-07
UniRef50_Q4V008 Cluster: Oxidoreductase; n=4; Proteobacteria|Rep...    58   8e-07
UniRef50_Q4Q5X1 Cluster: Aldehyde reductase, putative; n=75; cel...    58   8e-07
UniRef50_UPI0000499B0E Cluster: oxidoreductase, aldo/keto reduct...    57   1e-06
UniRef50_A6WDZ5 Cluster: Aldo/keto reductase; n=5; Bacteria|Rep:...    57   1e-06
UniRef50_UPI00015B4912 Cluster: PREDICTED: similar to aldo-keto ...    57   1e-06
UniRef50_Q11DV1 Cluster: Aldo/keto reductase; n=10; Alphaproteob...    57   1e-06
UniRef50_Q0SFM4 Cluster: Probable 2,5-didehydrogluconate reducta...    57   1e-06
UniRef50_A2EYY6 Cluster: Oxidoreductase, aldo/keto reductase fam...    57   1e-06
UniRef50_A6SJ74 Cluster: Putative uncharacterized protein; n=1; ...    57   1e-06
UniRef50_Q6CEJ0 Cluster: Yarrowia lipolytica chromosome B of str...    56   2e-06
UniRef50_Q59Z55 Cluster: Potential aldo/keto reductase; n=6; Sac...    56   2e-06
UniRef50_Q9HM42 Cluster: Alcohol dehydrogenase related protein; ...    56   2e-06
UniRef50_Q5NLW3 Cluster: Putative oxidoreductase; n=1; Zymomonas...    56   2e-06
UniRef50_A7P424 Cluster: Chromosome chr1 scaffold_5, whole genom...    56   2e-06
UniRef50_Q76L36 Cluster: Conjugated polyketone reductase C2; n=1...    56   2e-06
UniRef50_A7D7K7 Cluster: Aldo/keto reductase; n=1; Halorubrum la...    56   2e-06
UniRef50_Q5T2L2 Cluster: Aldo-keto reductase family 1 member C-l...    56   2e-06
UniRef50_Q9P734 Cluster: Related to 2, 5-diketo-D-gluconic acid ...    56   3e-06
UniRef50_Q5B5R6 Cluster: Putative uncharacterized protein; n=1; ...    56   3e-06
UniRef50_UPI000038E317 Cluster: hypothetical protein Faci_030017...    55   4e-06
UniRef50_Q28P63 Cluster: Aldo/keto reductase; n=4; Rhodobacterac...    55   4e-06
UniRef50_A6W8E7 Cluster: 2,5-didehydrogluconate reductase; n=3; ...    55   4e-06
UniRef50_A0AWM8 Cluster: Aldo/keto reductase; n=4; Actinomycetal...    55   4e-06
UniRef50_P15339 Cluster: 2,5-diketo-D-gluconic acid reductase B;...    55   4e-06
UniRef50_Q14LA8 Cluster: Putative aldo/keto reductase oxidoreduc...    55   6e-06
UniRef50_A1RB46 Cluster: 2,5-diketo-D-gluconate reductase; n=1; ...    55   6e-06
UniRef50_O13848 Cluster: NADH/NADPH dependent indole-3-acetaldeh...    55   6e-06
UniRef50_A7TLC4 Cluster: Putative uncharacterized protein; n=1; ...    55   6e-06
UniRef50_Q89JN4 Cluster: Oxidoreductase; n=8; Rhizobiales|Rep: O...    54   7e-06
UniRef50_A7LSN6 Cluster: Putative uncharacterized protein; n=3; ...    54   7e-06
UniRef50_A7BES9 Cluster: Putative uncharacterized protein; n=1; ...    54   7e-06
UniRef50_Q7PLK6 Cluster: CG40064-PA; n=1; Drosophila melanogaste...    54   7e-06
UniRef50_Q64W37 Cluster: 2,5-diketo-D-gluconic acid reductase; n...    54   1e-05
UniRef50_Q6XUT6 Cluster: Oxido-reductase/dehydratase; n=3; Bacte...    54   1e-05
UniRef50_A2RMU6 Cluster: Oxidoreductase, aldo/keto reductase fam...    53   2e-05
UniRef50_A2FPE2 Cluster: Oxidoreductase, aldo/keto reductase fam...    53   2e-05
UniRef50_Q4P1G1 Cluster: Putative uncharacterized protein; n=1; ...    53   2e-05
UniRef50_Q5FT75 Cluster: Putative 2,5-diketo-D-gluconic acid red...    53   2e-05
UniRef50_Q8ZH36 Cluster: 2,5-diketo-D-gluconic acid reductase B;...    53   2e-05
UniRef50_P76234 Cluster: Uncharacterized protein yeaE; n=39; Bac...    52   3e-05
UniRef50_Q15NA5 Cluster: Aldo/keto reductase; n=2; Gammaproteoba...    52   4e-05
UniRef50_Q03UP2 Cluster: Aryl-alcohol dehydrogenase family enzym...    52   4e-05
UniRef50_A3LWP0 Cluster: Aldo/keto reductase; n=7; Saccharomycet...    52   4e-05
UniRef50_Q1M4Z6 Cluster: Putative aldo-keto reductase/oxidase; n...    51   7e-05
UniRef50_A2QB88 Cluster: Contig An01c0460, complete genome. prec...    51   7e-05
UniRef50_UPI00005F9591 Cluster: COG0656: Aldo/keto reductases, r...    51   9e-05
UniRef50_A3H9Y8 Cluster: Aldo/keto reductase; n=2; Caldivirga ma...    51   9e-05
UniRef50_Q8PN61 Cluster: Oxidoreductase; n=5; Proteobacteria|Rep...    50   1e-04
UniRef50_Q1DLF1 Cluster: Putative uncharacterized protein; n=1; ...    50   1e-04
UniRef50_Q5V663 Cluster: Aldehyde reductase; n=6; Halobacteriace...    50   1e-04
UniRef50_Q5V398 Cluster: Oxidoreductase aldo/keto reductase fami...    50   1e-04
UniRef50_Q64UK5 Cluster: Aldo/keto reductase family oxidoreducta...    50   2e-04
UniRef50_A2WWZ1 Cluster: Putative uncharacterized protein; n=1; ...    50   2e-04
UniRef50_Q17DN1 Cluster: Aldo-keto reductase; n=1; Aedes aegypti...    50   2e-04
UniRef50_Q4PHK0 Cluster: Putative uncharacterized protein; n=1; ...    50   2e-04
UniRef50_Q2CAL9 Cluster: 2,5-didehydrogluconate reductase; n=2; ...    49   3e-04
UniRef50_Q21EY6 Cluster: Aldo/keto reductase; n=1; Saccharophagu...    49   3e-04
UniRef50_A0JTR5 Cluster: Aldo/keto reductase; n=2; Actinomycetal...    49   4e-04
UniRef50_Q013C5 Cluster: Glycerol dehydrogenase, putative; n=2; ...    49   4e-04
UniRef50_Q0CK00 Cluster: Predicted protein; n=1; Aspergillus ter...    49   4e-04
UniRef50_Q97UV9 Cluster: Oxidoreductase; n=1; Sulfolobus solfata...    49   4e-04
UniRef50_Q39MY8 Cluster: Aldo/keto reductase; n=10; Bacteria|Rep...    48   5e-04
UniRef50_Q2FGN2 Cluster: Oxidoreductase, aldo/keto reductase fam...    48   5e-04
UniRef50_Q4WP69 Cluster: Aldehyde reductase, putative; n=1; Aspe...    48   5e-04
UniRef50_Q5V6N9 Cluster: Alcohol dehydrogenase; n=2; Halobacteri...    48   5e-04
UniRef50_Q4HND9 Cluster: Oxidoreductase, aldo/keto reductase fam...    48   6e-04
UniRef50_A5BF24 Cluster: Putative uncharacterized protein; n=1; ...    48   6e-04
UniRef50_Q9USV2 Cluster: Xylose and arabinose reductase; n=2; Sc...    48   6e-04
UniRef50_A7D6I8 Cluster: Aldo/keto reductase; n=1; Halorubrum la...    48   6e-04
UniRef50_Q03BE0 Cluster: Aldo/keto reductase family enzyme; n=5;...    48   9e-04
UniRef50_Q4WI64 Cluster: Aldehyde reductase, putative; n=22; Pez...    48   9e-04
UniRef50_A5BYJ4 Cluster: Putative uncharacterized protein; n=1; ...    47   0.001
UniRef50_Q5B034 Cluster: Putative uncharacterized protein; n=1; ...    47   0.001
UniRef50_Q1Q8W8 Cluster: Aldo/keto reductase; n=1; Psychrobacter...    46   0.003
UniRef50_Q2H7A8 Cluster: Putative uncharacterized protein; n=1; ...    46   0.003
UniRef50_Q8YXI8 Cluster: All1225 protein; n=9; Cyanobacteria|Rep...    46   0.003
UniRef50_Q03I00 Cluster: Aryl-alcohol dehydrogenase related enzy...    46   0.003
UniRef50_A6PR52 Cluster: Aldo/keto reductase; n=1; Victivallis v...    46   0.003
UniRef50_Q98IA6 Cluster: Aryl-alcohol dehydrogenase; n=1; Mesorh...    45   0.005
UniRef50_A0VAL7 Cluster: Aldo/keto reductase; n=2; Proteobacteri...    45   0.005
UniRef50_A6SI80 Cluster: Putative uncharacterized protein; n=1; ...    45   0.005
UniRef50_Q6L139 Cluster: 2,5-diketo-D-gluconic acid reductase; n...    45   0.005
UniRef50_Q07551 Cluster: NADPH-dependent alpha-keto amide reduct...    45   0.005
UniRef50_Q096Q3 Cluster: Oxidoreductase, aldo reductase; n=1; St...    45   0.006
UniRef50_Q3E9M9 Cluster: Uncharacterized protein At5g01670.2; n=...    45   0.006
UniRef50_Q55ML8 Cluster: Putative uncharacterized protein; n=2; ...    45   0.006
UniRef50_A1CCJ1 Cluster: Aldo/keto reductase; n=2; Trichocomacea...    45   0.006
UniRef50_A7D761 Cluster: Aldo/keto reductase; n=2; Halobacteriac...    45   0.006
UniRef50_Q89RG2 Cluster: Aldo/keto reductase; n=11; Bacteria|Rep...    44   0.008
UniRef50_A3VRL4 Cluster: Putative uncharacterized protein; n=1; ...    44   0.008
UniRef50_Q9V2P1 Cluster: Myo-inositol degradation; n=5; Archaea|...    44   0.008
UniRef50_UPI000023DF27 Cluster: hypothetical protein FG07276.1; ...    44   0.011
UniRef50_Q97L01 Cluster: Fe-S oxidoreductase; n=4; Clostridium|R...    44   0.011
UniRef50_Q97KZ9 Cluster: Fe-S oxidoreductase; n=6; cellular orga...    44   0.011
UniRef50_Q660Z5 Cluster: Aldose reductase, putative; n=3; Borrel...    44   0.011
UniRef50_Q5FHT2 Cluster: Aldehyde reductase; n=4; Lactobacillus|...    44   0.014
UniRef50_A5UXT4 Cluster: Aldo/keto reductase; n=2; Roseiflexus|R...    44   0.014
UniRef50_Q1PV10 Cluster: Putative uncharacterized protein; n=1; ...    43   0.018
UniRef50_Q16CS5 Cluster: 2,5-diketo-D-gluconic acid reductase B,...    43   0.018
UniRef50_Q0B0F0 Cluster: Oxidoreductase; n=1; Syntrophomonas wol...    43   0.018
UniRef50_A1S0T5 Cluster: Aldo/keto reductase; n=2; Thermoprotei|...    43   0.018
UniRef50_A6FYX9 Cluster: Oxidoreductase; n=1; Plesiocystis pacif...    43   0.024
UniRef50_Q31SB1 Cluster: Putative uncharacterized protein; n=2; ...    42   0.032
UniRef50_Q97V56 Cluster: Dehydrogenase; n=8; Thermoprotei|Rep: D...    42   0.032
UniRef50_A7PNT1 Cluster: Chromosome chr8 scaffold_23, whole geno...    42   0.043
UniRef50_Q18903 Cluster: Putative uncharacterized protein C56G3....    42   0.043
UniRef50_Q5V0P8 Cluster: Oxidoreductase; n=2; Halobacteriaceae|R...    42   0.043
UniRef50_Q0W0V6 Cluster: Predicted aldo/keto reductase; n=2; Eur...    42   0.043
UniRef50_P82125 Cluster: 1,5-anhydro-D-fructose reductase; n=1; ...    42   0.043
UniRef50_Q49V75 Cluster: Putative oxidoreductase; n=1; Staphyloc...    42   0.056
UniRef50_A6W292 Cluster: Aldo/keto reductase; n=9; Bacteria|Rep:...    42   0.056
UniRef50_A6DRY4 Cluster: Aldo/keto reductase; n=1; Lentisphaera ...    42   0.056
UniRef50_A3DNU7 Cluster: Aldo/keto reductase; n=3; Desulfurococc...    42   0.056
UniRef50_A6S357 Cluster: Putative uncharacterized protein; n=2; ...    41   0.075
UniRef50_Q2J7H2 Cluster: Aldo/keto reductase; n=16; Bacteria|Rep...    41   0.099
UniRef50_Q4WF80 Cluster: Glycerol dehydrogenase (GCY1), putative...    41   0.099
UniRef50_Q97U17 Cluster: Oxidoreductase, aldo/keto reductase fam...    41   0.099
UniRef50_Q7D001 Cluster: AGR_C_2023p; n=14; Proteobacteria|Rep: ...    40   0.13 
UniRef50_Q097V7 Cluster: MocA; n=1; Stigmatella aurantiaca DW4/3...    40   0.13 
UniRef50_A6SUJ2 Cluster: Uncharacterized conserved protein; n=2;...    40   0.13 
UniRef50_A0JVH3 Cluster: Aldo/keto reductase; n=17; Bacteria|Rep...    40   0.13 
UniRef50_Q6NKP1 Cluster: At5g53580; n=18; cellular organisms|Rep...    40   0.13 
UniRef50_A1DD54 Cluster: Aldo/keto reductase; n=3; Trichocomacea...    40   0.13 
UniRef50_Q5V1M9 Cluster: Oxidoreductase aldo/keto reductase fami...    40   0.13 
UniRef50_Q8EVP7 Cluster: Putative oxidoreductase; n=3; Bacteria|...    40   0.17 
UniRef50_Q7NK63 Cluster: Gll1617 protein; n=1; Gloeobacter viola...    40   0.17 
UniRef50_Q1EZH4 Cluster: Aldo/keto reductase:4Fe-4S ferredoxin, ...    40   0.17 
UniRef50_A1SY15 Cluster: Aldo/keto reductase; n=1; Psychromonas ...    40   0.17 
UniRef50_A0L1A2 Cluster: Aldo/keto reductase; n=8; Gammaproteoba...    40   0.17 
UniRef50_A4IJ00 Cluster: LOC548351 protein; n=1; Xenopus tropica...    40   0.23 
UniRef50_A3WP89 Cluster: Aldo/keto reductase; n=1; Idiomarina ba...    40   0.23 
UniRef50_A0L4P0 Cluster: Aldo/keto reductase; n=1; Magnetococcus...    40   0.23 
UniRef50_Q94A68 Cluster: Uncharacterized oxidoreductase At1g0669...    40   0.23 
UniRef50_Q98EU0 Cluster: Oxidoreductase; MocA; n=27; Bacteria|Re...    39   0.30 
UniRef50_Q82JL9 Cluster: Putative oxidoreductase; n=2; Streptomy...    39   0.30 
UniRef50_Q3AEN5 Cluster: Oxidoreductase, aldo/keto reductase fam...    39   0.30 
UniRef50_Q1FGT0 Cluster: Aldo/keto reductase; n=1; Clostridium p...    39   0.30 
UniRef50_Q0RGM0 Cluster: Putative aldoketoreductase; n=2; Franki...    39   0.30 
UniRef50_Q9VGF3 Cluster: CG18547-PA; n=7; Endopterygota|Rep: CG1...    39   0.30 
UniRef50_Q5KKZ8 Cluster: Aldo-keto reductase, putative; n=2; Fil...    39   0.30 
UniRef50_A0QHX8 Cluster: General stress protein 69; n=2; Mycobac...    39   0.40 
UniRef50_Q295T6 Cluster: GA14985-PA; n=1; Drosophila pseudoobscu...    39   0.40 
UniRef50_Q979I4 Cluster: Aldo / keto reductase; n=3; Archaea|Rep...    39   0.40 
UniRef50_Q8ZU65 Cluster: Aldo-keto reductase, putative; n=4; The...    39   0.40 
UniRef50_UPI0000DAE567 Cluster: hypothetical protein Rgryl_01000...    38   0.53 
UniRef50_Q08NK7 Cluster: Aldo/keto reductase; n=1; Stigmatella a...    38   0.53 
UniRef50_A6BIJ0 Cluster: Putative uncharacterized protein; n=1; ...    38   0.53 
UniRef50_A6R5B4 Cluster: NAD(P)H-dependent D-xylose reductase; n...    38   0.53 
UniRef50_Q4JCC1 Cluster: 2,5-diketo-D-gluconic acid reductase A;...    38   0.53 
UniRef50_Q8DK16 Cluster: Tlr1054 protein; n=6; Cyanobacteria|Rep...    38   0.69 
UniRef50_Q03X89 Cluster: Aryl-alcohol dehydrogenase family enzym...    38   0.69 
UniRef50_A5CYR4 Cluster: Predicted oxidoreductases; n=2; Clostri...    38   0.69 
UniRef50_A2UBC7 Cluster: Aldo/keto reductase; n=3; cellular orga...    38   0.69 
UniRef50_A4R217 Cluster: Putative uncharacterized protein; n=1; ...    38   0.69 
UniRef50_A5UJH5 Cluster: Predicted oxidoreductase, aldo/keto red...    38   0.69 
UniRef50_O66660 Cluster: Putative uncharacterized protein; n=1; ...    38   0.92 
UniRef50_Q0AQX2 Cluster: Aldo/keto reductase; n=1; Maricaulis ma...    38   0.92 
UniRef50_A0YSM3 Cluster: Probable oxidoreductase; n=1; Lyngbya s...    38   0.92 
UniRef50_Q5ASJ7 Cluster: Putative uncharacterized protein; n=1; ...    38   0.92 
UniRef50_UPI0001556575 Cluster: PREDICTED: similar to Aldo-keto ...    37   1.2  
UniRef50_Q8UIN0 Cluster: Oxidoreductase; n=3; Alphaproteobacteri...    37   1.2  
UniRef50_Q8EUX1 Cluster: Aldo/keto reductase family oxidoreducta...    37   1.2  
UniRef50_Q3ZWR6 Cluster: Oxidoreductase, aldo reductase; n=3; De...    37   1.2  
UniRef50_Q7D3N9 Cluster: AGR_pAT_274p; n=3; Proteobacteria|Rep: ...    37   1.2  
UniRef50_Q022Y6 Cluster: Aldo/keto reductase precursor; n=2; Sol...    37   1.2  
UniRef50_A7HEV1 Cluster: Aldo/keto reductase; n=13; Bacteria|Rep...    37   1.2  
UniRef50_A6WAE5 Cluster: Aldo/keto reductase; n=1; Kineococcus r...    37   1.2  
UniRef50_A6LWU9 Cluster: Aldo/keto reductase; n=3; Clostridium|R...    37   1.2  
UniRef50_A1RJL6 Cluster: Aldo/keto reductase; n=37; Bacteria|Rep...    37   1.2  
UniRef50_Q6CWB9 Cluster: Similarities with sp|Q12458 Saccharomyc...    37   1.2  
UniRef50_A4QYA4 Cluster: Putative uncharacterized protein; n=1; ...    37   1.2  
UniRef50_A1CGI8 Cluster: Aldo-keto reductase (AKR13), puatative;...    37   1.2  
UniRef50_Q2NFN7 Cluster: Predicted oxidoreductase; n=1; Methanos...    37   1.2  
UniRef50_Q89JX0 Cluster: Oxidoreductase; n=26; Bacteria|Rep: Oxi...    37   1.6  
UniRef50_Q93KW0 Cluster: Putative oxidoreductase; n=1; Streptomy...    37   1.6  
UniRef50_Q0AL14 Cluster: Aldo/keto reductase; n=1; Maricaulis ma...    37   1.6  
UniRef50_A3IX63 Cluster: Putative oxidoreductase; n=1; Cyanothec...    37   1.6  
UniRef50_A0LHW7 Cluster: Aldo/keto reductase precursor; n=1; Syn...    37   1.6  
UniRef50_A5UNN5 Cluster: Predicted oxidoreductase, aldo/keto red...    37   1.6  
UniRef50_Q837G5 Cluster: Oxidoreductase, aldo/keto reductase 2 f...    36   2.1  
UniRef50_A7BLU0 Cluster: Aldo/keto reductase family; n=1; Beggia...    36   2.1  
UniRef50_A3I2P1 Cluster: Putative oxidoreductase-possibly Aldo/k...    36   2.1  
UniRef50_Q2RWD2 Cluster: Aldo/keto reductase; n=1; Rhodospirillu...    36   2.8  
UniRef50_A0V7Q3 Cluster: Aldo/keto reductase precursor; n=5; Pro...    36   2.8  
UniRef50_Q2SL81 Cluster: Predicted oxidoreductase; n=10; Bacteri...    36   3.7  
UniRef50_Q1IXS0 Cluster: Putative aldehyde reductase; n=1; Deino...    36   3.7  
UniRef50_Q1IXM8 Cluster: Aldo/keto reductase; n=2; Bacteria|Rep:...    36   3.7  
UniRef50_A5VEK4 Cluster: Aldo/keto reductase; n=5; Bacteria|Rep:...    36   3.7  
UniRef50_A0K1H5 Cluster: Aldo/keto reductase; n=6; Actinomycetal...    36   3.7  
UniRef50_Q0DHN0 Cluster: Os05g0456200 protein; n=2; Oryza sativa...    36   3.7  
UniRef50_A2XRY8 Cluster: Putative uncharacterized protein; n=2; ...    36   3.7  
UniRef50_P49249 Cluster: IN2-2 protein; n=6; Magnoliophyta|Rep: ...    36   3.7  
UniRef50_Q5ZTU6 Cluster: D-xylose reductase III; n=5; Legionella...    35   4.9  
UniRef50_Q1GLY3 Cluster: Aldo/keto reductase; n=9; Proteobacteri...    35   4.9  
UniRef50_A5FZX7 Cluster: Aldo/keto reductase precursor; n=4; Bac...    35   4.9  
UniRef50_A4E7S8 Cluster: Putative uncharacterized protein; n=1; ...    35   4.9  
UniRef50_Q983C8 Cluster: Oxido-reductase, and dehydratase; MocA;...    35   6.5  
UniRef50_Q8EZ83 Cluster: Aldo/keto reductase family protein; n=1...    35   6.5  
UniRef50_Q87SA8 Cluster: Oxidoreductase Tas, aldo/keto reductase...    35   6.5  
UniRef50_Q2BBT9 Cluster: Probable oxidoreductase protein; n=2; B...    35   6.5  
UniRef50_Q1IQ78 Cluster: Aldo/keto reductase; n=1; Acidobacteria...    35   6.5  
UniRef50_Q118N2 Cluster: Putative uncharacterized protein; n=1; ...    35   6.5  
UniRef50_Q0FFB1 Cluster: Aldo/keto reductase; n=1; alpha proteob...    35   6.5  
UniRef50_Q23TY7 Cluster: Oxidoreductase, aldo/keto reductase fam...    35   6.5  
UniRef50_P77256 Cluster: Uncharacterized oxidoreductase ydjG; n=...    35   6.5  
UniRef50_P40691 Cluster: Auxin-induced protein PCNT115; n=65; ce...    35   6.5  
UniRef50_Q982V1 Cluster: Mll8482 protein; n=9; Alphaproteobacter...    34   8.6  
UniRef50_Q8YAN3 Cluster: Lmo0084 protein; n=11; Listeria monocyt...    34   8.6  
UniRef50_Q88TP1 Cluster: Oxidoreductase; n=3; Bacteria|Rep: Oxid...    34   8.6  
UniRef50_Q7UZ40 Cluster: Putative oxidoreductase-possibly Aldo/k...    34   8.6  
UniRef50_Q3A5H0 Cluster: Predicted oxidoreductase, aryl-alcohol ...    34   8.6  
UniRef50_Q2JHT1 Cluster: Aldo/keto reductase Tas; n=25; cellular...    34   8.6  
UniRef50_A5ZM37 Cluster: Putative uncharacterized protein; n=1; ...    34   8.6  
UniRef50_Q338B1 Cluster: Auxin-induced protein PCNT115, putative...    34   8.6  
UniRef50_Q5KKC5 Cluster: Putative uncharacterized protein; n=2; ...    34   8.6  
UniRef50_Q9YBV5 Cluster: Putative uncharacterized protein; n=1; ...    34   8.6  
UniRef50_Q5V3K3 Cluster: Oxidoreductase aldo/keto reductase fami...    34   8.6  
UniRef50_Q5V161 Cluster: Aldo/keto reductase; n=2; Halobacteriac...    34   8.6  

>UniRef50_Q5BLA6 Cluster: Zgc:110782; n=2; Danio rerio|Rep:
           Zgc:110782 - Danio rerio (Zebrafish) (Brachydanio rerio)
          Length = 287

 Score =  138 bits (335), Expect = 3e-31
 Identities = 71/149 (47%), Positives = 97/149 (65%)
 Frame = +3

Query: 252 LNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPK 431
           L +G +MP +GL T+K+     + Q+V  AL+AGYR FDTAA+YGNE +L    K+LLPK
Sbjct: 8   LMSGTQMPLLGLGTYKLQDHEQLKQSVSCALQAGYRAFDTAAVYGNEAHLGQVLKELLPK 67

Query: 432 YKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLDFENRN 611
           Y L R D+FIISKL P ++G  A  +     +L  L  +YIDLYL+H PG+  LD E+  
Sbjct: 68  YGLIREDVFIISKLAPSDHGLRA--KEGCLRSLEQLDCEYIDLYLIHWPGMEGLDPEDSR 125

Query: 612 SSRIRKQTWATLVDLYHDHKIRALGVSNY 698
            S  R Q+WATL + +   + +A+GVSNY
Sbjct: 126 HSEYRAQSWATLEEFHASGQFKAIGVSNY 154


>UniRef50_Q5XJM7 Cluster: Zgc:101765; n=5; Eumetazoa|Rep: Zgc:101765
           - Danio rerio (Zebrafish) (Brachydanio rerio)
          Length = 288

 Score =  136 bits (329), Expect = 1e-30
 Identities = 70/151 (46%), Positives = 91/151 (60%)
 Frame = +3

Query: 252 LNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPK 431
           LNN ++MP +GL TF++         VD ALKAGYR FDTAA+Y NE +L  A + LLPK
Sbjct: 10  LNNDIQMPLLGLGTFRLQGQEDTYSAVDAALKAGYRAFDTAAVYRNEAHLGHALRCLLPK 69

Query: 432 YKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLDFENRN 611
           + L R D+FI SKL P + G  A        +L  LGL YIDLYL+H PG   L   ++ 
Sbjct: 70  HGLSREDVFITSKLGPKDQGSKA--RNGCQKSLEQLGLGYIDLYLIHWPGTQGLPVGDKR 127

Query: 612 SSRIRKQTWATLVDLYHDHKIRALGVSNYFI 704
           +   R Q+W  L + Y + K RA+GVSNY +
Sbjct: 128 NPENRAQSWRVLEEFYSEGKFRAIGVSNYTV 158


>UniRef50_UPI00015B5BD7 Cluster: PREDICTED: similar to aldo-keto
           reductase; n=1; Nasonia vitripennis|Rep: PREDICTED:
           similar to aldo-keto reductase - Nasonia vitripennis
          Length = 310

 Score =  130 bits (315), Expect = 7e-29
 Identities = 61/151 (40%), Positives = 94/151 (62%)
 Frame = +3

Query: 252 LNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPK 431
           LNNG +MP +G+ T+K+     + + +D++   G+R  DTA +Y NE  +  A K+LLPK
Sbjct: 28  LNNGYDMPLVGIGTYKVRGREVIKRVIDESFAVGFRSIDTAVVYRNEEDIGLALKELLPK 87

Query: 432 YKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLDFENRN 611
           Y LKR DIFI SKL P + G      ++  ++L  L   Y+DLYL+H PG  ++   + +
Sbjct: 88  YNLKREDIFITSKLSPSDNGDPDKIRKSVEDSLKALDTSYLDLYLIHWPGASRILENSPD 147

Query: 612 SSRIRKQTWATLVDLYHDHKIRALGVSNYFI 704
           + ++R  TWATLV+L     +R++GVSNY +
Sbjct: 148 NPKLRVTTWATLVELQQKGLLRSIGVSNYTV 178


>UniRef50_UPI0000DB6EE9 Cluster: PREDICTED: similar to C35D10.6;
           n=2; Endopterygota|Rep: PREDICTED: similar to C35D10.6 -
           Apis mellifera
          Length = 292

 Score =  124 bits (299), Expect = 6e-27
 Identities = 64/151 (42%), Positives = 88/151 (58%)
 Frame = +3

Query: 252 LNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPK 431
           L++G +MP IG  T+K+     V Q VD++L  G+R  DTA  Y NE  + +A K LLPK
Sbjct: 10  LSSGYDMPLIGFGTYKIQGRELVYQVVDESLNVGFRSIDTAVGYRNEEDIGYALKNLLPK 69

Query: 432 YKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLDFENRN 611
           Y L+R DIFI +KL P   G     E+    +L      YIDLYL+H PG  ++   + N
Sbjct: 70  YNLQRSDIFITTKLPPSVNGDPKGIEQCVQKSLKAFNTTYIDLYLIHWPGATRIPETSTN 129

Query: 612 SSRIRKQTWATLVDLYHDHKIRALGVSNYFI 704
           +  +R +TW  LVDL     IR++GVSN+ I
Sbjct: 130 NPSLRAKTWNKLVDLKKQGFIRSIGVSNFTI 160


>UniRef50_Q5TNP1 Cluster: ENSANGP00000029046; n=2; Culicidae|Rep:
           ENSANGP00000029046 - Anopheles gambiae str. PEST
          Length = 331

 Score =  117 bits (282), Expect = 7e-25
 Identities = 63/163 (38%), Positives = 93/163 (57%), Gaps = 10/163 (6%)
 Frame = +3

Query: 246 FTLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLL 425
           F LN G ++P  G  T+++     + Q +D AL+AGYR  DTA +Y NE Y+  A K LL
Sbjct: 34  FKLNTGFDIPLAGFGTYQIHGQELIYQVLDYALEAGYRHIDTAVVYRNEEYIGTALKTLL 93

Query: 426 PKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGI------- 584
           PKY LKR DIFI SKL+  +    A  E+    +L+NL  DY+DLYL+H PG+       
Sbjct: 94  PKYNLKREDIFITSKLISQSGKDEAFVEQMVRKSLANLQTDYLDLYLIHWPGVSGKCGRW 153

Query: 585 ---YKLDFENRNSSRIRKQTWATLVDLYHDHKIRALGVSNYFI 704
              + +   + ++ + R  +W  L  L  +  +R++GVSNY +
Sbjct: 154 KWLFGMQVTHPDNVKYRAASWNALSKLEREGCLRSIGVSNYTV 196


>UniRef50_Q6WGK4 Cluster: Aldose reductase; n=1; Pristionchus
           pacificus|Rep: Aldose reductase - Pristionchus pacificus
          Length = 293

 Score =  115 bits (276), Expect = 4e-24
 Identities = 59/145 (40%), Positives = 88/145 (60%)
 Frame = +3

Query: 270 MPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPKYKLKRG 449
           MP IG+ T+++     +  T+D+A + GYR  DTA +Y NE  L      LL K+ LKR 
Sbjct: 16  MPMIGVGTYQVQSQSVLTDTIDEAFRLGYRFIDTAQIYRNEAILGRILPDLLEKHSLKRE 75

Query: 450 DIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLDFENRNSSRIRK 629
           DIFI SK+ P N G G  T ++   +L++L   YIDL L+H PG  +L   ++++++ R 
Sbjct: 76  DIFITSKVSPINQGKGK-TSKSVLKSLTDLQTPYIDLVLIHWPGTSRLKSNHKDNAKFRA 134

Query: 630 QTWATLVDLYHDHKIRALGVSNYFI 704
           +T+  L  L  + KIR++GVSNY I
Sbjct: 135 ETYVELETLMDEGKIRSIGVSNYEI 159


>UniRef50_Q1U9L6 Cluster: 2,5-didehydrogluconate reductase; n=3;
           Lactobacillus|Rep: 2,5-didehydrogluconate reductase -
           Lactobacillus reuteri 100-23
          Length = 288

 Score =  113 bits (272), Expect = 1e-23
 Identities = 65/151 (43%), Positives = 93/151 (61%)
 Frame = +3

Query: 246 FTLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLL 425
           F LNNGV++P +G  TF+        Q V +A++ GYR  DTAA+YGNE     A  K +
Sbjct: 11  FNLNNGVKIPCVGYGTFRTPADVAE-QAVKEAIETGYRHIDTAAVYGNEE----AVGKGI 65

Query: 426 PKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLDFEN 605
               +KR D+F+ SKL   N G    T++AF  TL  L +DY+DLYL+H P   K  F +
Sbjct: 66  KDSGIKREDLFVTSKLWNTNRGYEQ-TKKAFQETLDRLQMDYLDLYLIHWPANEK-QFGD 123

Query: 606 RNSSRIRKQTWATLVDLYHDHKIRALGVSNY 698
            ++++I  +TW  + DLY++ KIRA+GVSN+
Sbjct: 124 -DAAKINAETWRAMEDLYNEGKIRAIGVSNF 153


>UniRef50_P70883 Cluster: AkrI; n=1; Butyrivibrio fibrisolvens|Rep:
           AkrI - Butyrivibrio fibrisolvens
          Length = 172

 Score =  110 bits (264), Expect = 1e-22
 Identities = 59/155 (38%), Positives = 86/155 (55%)
 Frame = +3

Query: 234 LPQQFTLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAF 413
           L  +  LNNG  +P  G  T+K+        +V  ALK GYR  DTAA Y NE ++  A 
Sbjct: 4   LTTRIKLNNGTAIPMFGYGTYKIKDQNEAYNSVRLALKNGYRHIDTAAFYENEKFVANAI 63

Query: 414 KKLLPKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKL 593
           K  + + + KR DIF+ SK      G    T  AF  T++ + +DY+DLYLVH P  Y  
Sbjct: 64  KDFMEESQTKREDIFVTSKAWKTELGYDK-TLAAFEKTMNEMQMDYLDLYLVHWPASYAF 122

Query: 594 DFENRNSSRIRKQTWATLVDLYHDHKIRALGVSNY 698
           D +  N++R   QTW  + ++Y   +++A+GVSN+
Sbjct: 123 DDDWENTNR---QTWKAMTEIYKSGRVKAIGVSNF 154


>UniRef50_Q54NR2 Cluster: Aldo-keto reductase; n=3; Dictyostelium
           discoideum AX4|Rep: Aldo-keto reductase - Dictyostelium
           discoideum AX4
          Length = 305

 Score =  108 bits (260), Expect = 3e-22
 Identities = 63/171 (36%), Positives = 97/171 (56%), Gaps = 8/171 (4%)
 Frame = +3

Query: 216 EDFKYILPQQFTLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEV 395
           E+  +I+  +  LN  ++MP +G+ TFK+     +++     L+ GYR  DTA++Y NE 
Sbjct: 10  ENENFIILNELNLNP-IKMPMLGIGTFKLNDIENIIKV---GLENGYRRIDTASMYNNEE 65

Query: 396 YLNFAFKKLLPKY------KLKRGDIFIISKLLPCNY--GGGAVTERAFHNTLSNLGLDY 551
            +     +++ K       K+KR D+FI SK   C++   G     +AF ++L  L LDY
Sbjct: 66  RIGKVLNEMVTKNDGLDGKKIKREDLFITSK---CSFMEQGYENALKAFESSLKKLQLDY 122

Query: 552 IDLYLVHNPGIYKLDFENRNSSRIRKQTWATLVDLYHDHKIRALGVSNYFI 704
           +D YL+H PG+  LD  +  +S  R QTW  L  LY D K+R++GVSNY I
Sbjct: 123 LDCYLIHWPGVKGLDGSDSGNSIQRAQTWRALEKLYQDKKVRSIGVSNYTI 173


>UniRef50_Q21274 Cluster: Putative uncharacterized protein; n=1;
           Caenorhabditis elegans|Rep: Putative uncharacterized
           protein - Caenorhabditis elegans
          Length = 301

 Score =  108 bits (259), Expect = 4e-22
 Identities = 62/165 (37%), Positives = 91/165 (55%), Gaps = 3/165 (1%)
 Frame = +3

Query: 222 FKYILPQQFTLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYL 401
           F  ++   F  ++G EMP IGL   ++     +  +++ ALK+GYR FDTA LY NE +L
Sbjct: 4   FTNVVGGAFKFSDGYEMPKIGLGISRIETQQDLDVSIEAALKSGYRQFDTANLYKNETFL 63

Query: 402 NFAFKKLLPKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNP- 578
             + KK LP++ L R D+FI +K+   N      TE+   N+L+ L  DY+DL L+H P 
Sbjct: 64  GNSLKKYLPQFGLTREDVFITTKVRTLNENTVEETEKQLANSLATLQTDYVDLLLIHYPR 123

Query: 579 --GIYKLDFENRNSSRIRKQTWATLVDLYHDHKIRALGVSNYFIW 707
                  D    N SR RK  W TL       ++R++GVSNY ++
Sbjct: 124 DRDTGNDDDYEINKSR-RKIVWQTLEKAKESGRVRSIGVSNYEVY 167


>UniRef50_Q18483 Cluster: Putative uncharacterized protein; n=2;
           Caenorhabditis|Rep: Putative uncharacterized protein -
           Caenorhabditis elegans
          Length = 287

 Score =  108 bits (259), Expect = 4e-22
 Identities = 59/155 (38%), Positives = 91/155 (58%)
 Frame = +3

Query: 240 QQFTLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKK 419
           +++  NN   MP IG+ T+++     + Q +D   K GYR  DTA +Y NE  +    +K
Sbjct: 4   REYVKNN---MPLIGIGTWQVQKEEILRQVIDAGFKEGYRFIDTAQVYNNEAKIGRILEK 60

Query: 420 LLPKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLDF 599
           LLP   LKR DI+I SKL P N G     E +   +LSNL ++Y+DL L+H PG   L  
Sbjct: 61  LLPANGLKREDIWITSKLAPSNAGVKKARE-SIEESLSNLKVEYLDLLLIHWPG-SSLKS 118

Query: 600 ENRNSSRIRKQTWATLVDLYHDHKIRALGVSNYFI 704
           EN  + ++R ++W  + ++  + K+R++GVSN+ I
Sbjct: 119 ENPANKKLRVESWNVMCEMMAEGKLRSVGVSNFEI 153


>UniRef50_Q17568 Cluster: Putative uncharacterized protein; n=1;
           Caenorhabditis elegans|Rep: Putative uncharacterized
           protein - Caenorhabditis elegans
          Length = 287

 Score =  107 bits (258), Expect = 6e-22
 Identities = 60/152 (39%), Positives = 84/152 (55%), Gaps = 1/152 (0%)
 Frame = +3

Query: 246 FTLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLL 425
           F L NG E+P + L T++      +   VD+ALK GYR FDTA  Y NE  L  A K LL
Sbjct: 2   FKLKNGQEIPKLALGTYE-AKGDQLFAAVDEALKVGYRSFDTAKYYENEKDLGLALKTLL 60

Query: 426 PKYKLKRGDIFIISKLLPCNYGGGA-VTERAFHNTLSNLGLDYIDLYLVHNPGIYKLDFE 602
           P++ +   DI++ SK+ P +    A +  +  + +L  L   Y+DL LVH P     +  
Sbjct: 61  PRHNICSEDIYLTSKVFPYSSKNAAELIRKDVNESLELLDRKYLDLVLVHYPRPLDTEDL 120

Query: 603 NRNSSRIRKQTWATLVDLYHDHKIRALGVSNY 698
           N N+   RK TW  L  L+ + KIR++GVSNY
Sbjct: 121 NENNKMYRKDTWIALEKLHAEGKIRSIGVSNY 152


>UniRef50_P91997 Cluster: Putative uncharacterized protein; n=4;
           Caenorhabditis|Rep: Putative uncharacterized protein -
           Caenorhabditis elegans
          Length = 297

 Score =  106 bits (255), Expect = 1e-21
 Identities = 61/151 (40%), Positives = 83/151 (54%)
 Frame = +3

Query: 252 LNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPK 431
           LN+G  +P +G  T+K+     V   +D AL AGYRMFDTA  Y NE  L  A K LLPK
Sbjct: 15  LNSGYNIPFVGFGTYKVTG-ENVPPAIDAALTAGYRMFDTAKYYLNEKELGEALKILLPK 73

Query: 432 YKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLDFENRN 611
           + L R D+F+ SK  P +             +L +L  DYID+YLVH P     D ++ N
Sbjct: 74  HGLSRSDVFLTSKFFPESKNCREACRGFVEESLQSLQTDYIDMYLVHYPKPNDSDNDDVN 133

Query: 612 SSRIRKQTWATLVDLYHDHKIRALGVSNYFI 704
           ++  RK  +  L +     K+R++GVSNY I
Sbjct: 134 NAEYRKIAYEVLEEAKAAGKVRSIGVSNYEI 164


>UniRef50_A6NPD6 Cluster: Putative uncharacterized protein; n=3;
           Bacteria|Rep: Putative uncharacterized protein -
           Bacteroides capillosus ATCC 29799
          Length = 287

 Score =  104 bits (250), Expect = 5e-21
 Identities = 60/152 (39%), Positives = 87/152 (57%)
 Frame = +3

Query: 243 QFTLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKL 422
           QF L+NG+ +PA+G  T+K G   + +  + +A+  GYR FDTA+ YG E  L  A    
Sbjct: 7   QFVLSNGLSIPAVGFGTYKTGDGDSAV--LSNAIAQGYRHFDTASFYGTETALGQA---- 60

Query: 423 LPKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLDFE 602
           + +  + R D F+ SKL     G  A   RAF  TL  LG DY+DLYL+H P   + D E
Sbjct: 61  VAESDIPREDFFLTSKLWKTEMGYDAAL-RAFDATLERLGTDYLDLYLIHWP---RPDLE 116

Query: 603 NRNSSRIRKQTWATLVDLYHDHKIRALGVSNY 698
             + +++ ++TW  L  LY    +RA+GVSN+
Sbjct: 117 LEDWAKLDRETWRALERLYESGLVRAIGVSNF 148


>UniRef50_A6ESC0 Cluster: ARA1; n=1; unidentified eubacterium
           SCB49|Rep: ARA1 - unidentified eubacterium SCB49
          Length = 280

 Score =  103 bits (248), Expect = 9e-21
 Identities = 58/155 (37%), Positives = 87/155 (56%)
 Frame = +3

Query: 234 LPQQFTLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAF 413
           + + F LNN + +PAIG  T++     T +  +  A+ AGY+  D AA+Y NE  +    
Sbjct: 1   MKEYFKLNNNINIPAIGFGTWQTPDGQTAINAIKTAIDAGYKHIDAAAIYKNEKGVGLGI 60

Query: 414 KKLLPKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKL 593
           K+      + R D+F+ SK+      G   T +AF NT+++L LDY+DLYL+H P     
Sbjct: 61  KEA----NIDRKDLFVTSKVWN-EQRGYENTLKAFDNTINDLQLDYLDLYLIHWPAAAH- 114

Query: 594 DFENRNSSRIRKQTWATLVDLYHDHKIRALGVSNY 698
            FE  N  ++   TW+ +  LY D KI+ALGVSN+
Sbjct: 115 QFE--NWKQLNNDTWSAMEKLYKDGKIKALGVSNF 147


>UniRef50_Q88SL1 Cluster: Oxidoreductase; n=51; Lactobacillales|Rep:
           Oxidoreductase - Lactobacillus plantarum
          Length = 286

 Score =  101 bits (243), Expect = 4e-20
 Identities = 59/157 (37%), Positives = 88/157 (56%), Gaps = 2/157 (1%)
 Frame = +3

Query: 234 LPQQFTLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAF 413
           L   +TLNNG ++P +G  T++         +V  ALKAGYR  DTAA YGNE  +    
Sbjct: 7   LTDTYTLNNGTKIPIVGFGTWQTPDGQVAYDSVLAALKAGYRHIDTAAAYGNEESVG--- 63

Query: 414 KKLLPKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVH--NPGIY 587
            K +    + R D+F+ +KL   ++G  A  ++A   +L+ LGLDY+DLYL+H  NP   
Sbjct: 64  -KAIADSGVAREDLFVTTKLWNADHGYDA-AKKALDTSLAKLGLDYVDLYLIHWPNPAAM 121

Query: 588 KLDFENRNSSRIRKQTWATLVDLYHDHKIRALGVSNY 698
           + ++E  N+      TW  + + Y   K RA+GVSN+
Sbjct: 122 RDNWEQLNA-----DTWRAMEEAYTARKARAIGVSNF 153


>UniRef50_Q5FLI5 Cluster: Aldehyde reductase; n=2; Bacteria|Rep:
           Aldehyde reductase - Lactobacillus acidophilus
          Length = 278

 Score =   99 bits (238), Expect = 2e-19
 Identities = 60/151 (39%), Positives = 86/151 (56%)
 Frame = +3

Query: 249 TLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLP 428
           TLNNG++MP +G   +++       Q V+D L+ GYR+ DTA +YGNE  +  A K    
Sbjct: 6   TLNNGIKMPRLGFGVYQIDDLAQAQQVVEDGLEVGYRLVDTAQIYGNEQAVGDAIK---- 61

Query: 429 KYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLDFENR 608
              + R DIFI SK+   +YG    T +AF +++  L LDYIDLYL+H P  Y  D+   
Sbjct: 62  HSNVPREDIFITSKIWVDDYGYDN-TLKAFDDSMKKLQLDYIDLYLIHKP--YN-DYYG- 116

Query: 609 NSSRIRKQTWATLVDLYHDHKIRALGVSNYF 701
                   TW  L  LY + +IRA+GVS+++
Sbjct: 117 --------TWRALERLYQEGRIRAIGVSSFW 139


>UniRef50_Q8F1G4 Cluster: Aldehyde reductase; n=8; Bacteria|Rep:
           Aldehyde reductase - Leptospira interrogans
          Length = 278

 Score = 99.5 bits (237), Expect = 2e-19
 Identities = 61/157 (38%), Positives = 84/157 (53%)
 Frame = +3

Query: 234 LPQQFTLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAF 413
           L Q   LNNG+ MP +GL  +K        + V +AL+AGYR  DTA +Y NEV +  A 
Sbjct: 8   LKQTIMLNNGISMPILGLGVWKTKSGKECKEAVLNALEAGYRHIDTARIYDNEVDVGQAI 67

Query: 414 KKLLPKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKL 593
           +    +  + R +IFI +KL   + G    T +A  N+L  LG+D++DLYL+H P   K 
Sbjct: 68  R----ESGIPRKEIFITTKLWNADQGSDK-TRKALENSLDRLGIDFVDLYLIHFPVTSK- 121

Query: 594 DFENRNSSRIRKQTWATLVDLYHDHKIRALGVSNYFI 704
                     R  +W  L  LYHD   +A+GVSNY I
Sbjct: 122 ----------RMDSWKELEKLYHDKLCKAIGVSNYTI 148


>UniRef50_Q838E0 Cluster: Oxidoreductase, aldo/keto reductase
           family; n=24; Bacilli|Rep: Oxidoreductase, aldo/keto
           reductase family - Enterococcus faecalis (Streptococcus
           faecalis)
          Length = 279

 Score = 99.1 bits (236), Expect = 3e-19
 Identities = 59/155 (38%), Positives = 88/155 (56%)
 Frame = +3

Query: 234 LPQQFTLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAF 413
           L    TLNNG ++P +GL  F++    T  + V++ +  GYR+ DTA +YGNE       
Sbjct: 5   LADTVTLNNGTKIPGMGLGVFQIPDEETA-KVVEEGIINGYRLIDTAQIYGNESGTGAGI 63

Query: 414 KKLLPKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKL 593
           K  L    L R D+F+ SK+   +      T +AF+++L  LGLDY+DLYL+H PG    
Sbjct: 64  KAGLAATGLNREDLFVTSKVWNAHISYDE-TIQAFNDSLERLGLDYLDLYLIHWPG---- 118

Query: 594 DFENRNSSRIRKQTWATLVDLYHDHKIRALGVSNY 698
                N+S   K++W  L  LY + K++A+GVSN+
Sbjct: 119 -----NNS--YKESWQALETLYAEGKVKAIGVSNF 146


>UniRef50_Q23320 Cluster: Putative uncharacterized protein; n=4;
           Caenorhabditis|Rep: Putative uncharacterized protein -
           Caenorhabditis elegans
          Length = 320

 Score = 97.9 bits (233), Expect = 6e-19
 Identities = 61/151 (40%), Positives = 83/151 (54%)
 Frame = +3

Query: 246 FTLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLL 425
           FTL+NGV MP+IGL T++M         + +A+ AGYR  DTA LY NE  +  A  +L 
Sbjct: 8   FTLSNGVLMPSIGLGTWQMTG-EEGKTVIRNAVLAGYRHIDTATLYQNEHQIGDALAELF 66

Query: 426 PKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLDFEN 605
            +  LKR DIFI +K   C+     V E A  N+L  L LDY+DLYL H P   K D   
Sbjct: 67  AEGILKREDIFITTKAF-CHEVAPDVVEEALRNSLKRLRLDYVDLYLAHIPASTKDDGSF 125

Query: 606 RNSSRIRKQTWATLVDLYHDHKIRALGVSNY 698
           R+  ++ +  W     +Y     +A+GVSN+
Sbjct: 126 RSDVKV-EDIWRGFEKVYGLGLTKAIGVSNF 155


>UniRef50_Q9X0A2 Cluster: Oxidoreductase, aldo/keto reductase
           family; n=21; Bacteria|Rep: Oxidoreductase, aldo/keto
           reductase family - Thermotoga maritima
          Length = 286

 Score = 95.9 bits (228), Expect = 2e-18
 Identities = 56/151 (37%), Positives = 90/151 (59%)
 Frame = +3

Query: 249 TLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLP 428
           TLNNGVEMP +G   F++    T  + V +A+K GYR+ DTAA Y NE  +  A K+ + 
Sbjct: 7   TLNNGVEMPILGYGVFQIPPEKTE-ECVYEAIKVGYRLIDTAASYMNEEGVGRAIKRAID 65

Query: 429 KYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLDFENR 608
           +  ++R ++F+ +KL   + G  + T++AF  +L  L L+YIDLYL+H P      F + 
Sbjct: 66  EGIVRREELFVTTKLWVSDVGYES-TKKAFEKSLKKLQLEYIDLYLIHQP------FGDV 118

Query: 609 NSSRIRKQTWATLVDLYHDHKIRALGVSNYF 701
           + +      W  + ++Y D  +RA+GVSN++
Sbjct: 119 HCA------WKAMEEMYKDGLVRAIGVSNFY 143


>UniRef50_Q05KR9 Cluster: Benzil reductase; n=5; Bacillales|Rep:
           Benzil reductase - Bacillus subtilis
          Length = 276

 Score = 95.9 bits (228), Expect = 2e-18
 Identities = 62/149 (41%), Positives = 81/149 (54%)
 Frame = +3

Query: 252 LNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPK 431
           L+NGVEMP  GL  FK+ +     ++V  A+K GYR  DTAA+Y NE  +    K    +
Sbjct: 11  LHNGVEMPWFGLGVFKVENGNEATESVKAAIKNGYRSIDTAAIYKNEEGVGIGIK----E 66

Query: 432 YKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLDFENRN 611
             + R ++FI SK+   +  G   T  AF  +L  L LDY+DLYL+H PG  K       
Sbjct: 67  SGVAREELFITSKVWNEDQ-GYETTLAAFEKSLERLQLDYLDLYLIHWPGKDKY------ 119

Query: 612 SSRIRKQTWATLVDLYHDHKIRALGVSNY 698
                K TW  L  LY D KIRA+GVSN+
Sbjct: 120 -----KDTWRALEKLYKDGKIRAIGVSNF 143


>UniRef50_Q5HR31 Cluster: Oxidoreductase, aldo/keto reductase
           family; n=3; Staphylococcus|Rep: Oxidoreductase,
           aldo/keto reductase family - Staphylococcus epidermidis
           (strain ATCC 35984 / RP62A)
          Length = 279

 Score = 94.3 bits (224), Expect = 8e-18
 Identities = 62/151 (41%), Positives = 86/151 (56%)
 Frame = +3

Query: 252 LNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPK 431
           LNNG  MPA+GL  +K+     + + V  AL AGYR FDTA  YGNE  L  A K     
Sbjct: 8   LNNGYPMPAVGLGVYKIAD-EQMEEVVRTALDAGYRAFDTAYFYGNEKALGSALKHS--- 63

Query: 432 YKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLDFENRN 611
             ++R ++FI SKL   +Y G   T   F+ +L NLGLDY+DL+L+H P       EN  
Sbjct: 64  -NVERDELFITSKLWN-DYQGYDQTIEYFNKSLDNLGLDYLDLFLIHWP------CEN-- 113

Query: 612 SSRIRKQTWATLVDLYHDHKIRALGVSNYFI 704
             ++  +++  L  LY + KI+A+GV N+ I
Sbjct: 114 -DQLYIESYKALEHLYEEGKIKAIGVCNFKI 143


>UniRef50_Q2V420 Cluster: Uncharacterized protein At2g37770.1; n=1;
           Arabidopsis thaliana|Rep: Uncharacterized protein
           At2g37770.1 - Arabidopsis thaliana (Mouse-ear cress)
          Length = 283

 Score = 93.1 bits (221), Expect = 2e-17
 Identities = 59/155 (38%), Positives = 82/155 (52%), Gaps = 4/155 (2%)
 Frame = +3

Query: 246 FTLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLL 425
           F LN G + P++GL T++      V   V  A+K GYR  D A +YGNE  +    KKL 
Sbjct: 8   FKLNTGAKFPSVGLGTWQASPGL-VGDAVAAAVKIGYRHIDCAQIYGNEKEIGAVLKKLF 66

Query: 426 PKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYK---LD 596
               +KR D+FI SKL   ++    V E A + TL +L L+Y+DLYL+H P   K   + 
Sbjct: 67  EDRVVKREDLFITSKLWCTDHDPQDVPE-ALNRTLKDLQLEYVDLYLIHWPARIKKGSVG 125

Query: 597 FENRNSSRIR-KQTWATLVDLYHDHKIRALGVSNY 698
            +  N   +    TW  +  LY   K RA+GVSN+
Sbjct: 126 IKPENLLPVDIPSTWKAMEALYDSGKARAIGVSNF 160


>UniRef50_Q0PGJ6 Cluster: Aldo-keto reductase; n=32;
           Magnoliophyta|Rep: Aldo-keto reductase - Arabidopsis
           thaliana (Mouse-ear cress)
          Length = 315

 Score = 93.1 bits (221), Expect = 2e-17
 Identities = 59/155 (38%), Positives = 82/155 (52%), Gaps = 4/155 (2%)
 Frame = +3

Query: 246 FTLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLL 425
           F LN G + P++GL T++      V   V  A+K GYR  D A +YGNE  +    KKL 
Sbjct: 8   FKLNTGAKFPSVGLGTWQASPGL-VGDAVAAAVKIGYRHIDCAQIYGNEKEIGAVLKKLF 66

Query: 426 PKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYK---LD 596
               +KR D+FI SKL   ++    V E A + TL +L L+Y+DLYL+H P   K   + 
Sbjct: 67  EDRVVKREDLFITSKLWCTDHDPQDVPE-ALNRTLKDLQLEYVDLYLIHWPARIKKGSVG 125

Query: 597 FENRNSSRIR-KQTWATLVDLYHDHKIRALGVSNY 698
            +  N   +    TW  +  LY   K RA+GVSN+
Sbjct: 126 IKPENLLPVDIPSTWKAMEALYDSGKARAIGVSNF 160


>UniRef50_P45376 Cluster: Aldose reductase; n=21; Bilateria|Rep:
           Aldose reductase - Mus musculus (Mouse)
          Length = 316

 Score = 93.1 bits (221), Expect = 2e-17
 Identities = 57/158 (36%), Positives = 84/158 (53%), Gaps = 9/158 (5%)
 Frame = +3

Query: 252 LNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPK 431
           LNNG +MP +GL T+K      V + V  A+  GYR  D A +Y NE  +  A ++ L +
Sbjct: 7   LNNGTKMPTLGLGTWKSPPGQ-VTEAVKVAIDLGYRHIDCAQVYQNEKEVGVALQEKLKE 65

Query: 432 YKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVH-------NPGIYK 590
             +KR D+FI+SKL  C +   ++ + AF  TLS+L LDY+DLYL+H        P  + 
Sbjct: 66  QVVKRQDLFIVSKLW-CTFHDKSMVKGAFQKTLSDLQLDYLDLYLIHWPTGFKPGPDYFP 124

Query: 591 LDFENR--NSSRIRKQTWATLVDLYHDHKIRALGVSNY 698
           LD       S      TW  +  L  +  ++ +GVSN+
Sbjct: 125 LDASGNVIPSDTDFVDTWTAMEQLVDEGLVKTIGVSNF 162


>UniRef50_P15121 Cluster: Aldose reductase; n=72; Eumetazoa|Rep:
           Aldose reductase - Homo sapiens (Human)
          Length = 316

 Score = 91.9 bits (218), Expect = 4e-17
 Identities = 60/165 (36%), Positives = 91/165 (55%), Gaps = 10/165 (6%)
 Frame = +3

Query: 234 LPQQFTLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAF 413
           +  +  LNNG +MP +GL T+K      V + V  A+  GYR  D A +Y NE  +  A 
Sbjct: 1   MASRLLLNNGAKMPILGLGTWKSPPGQ-VTEAVKVAIDVGYRHIDCAHVYQNENEVGVAI 59

Query: 414 KKLLPKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVH-----NP 578
           ++ L +  +KR ++FI+SKL  C Y    + + A   TLS+L LDY+DLYL+H      P
Sbjct: 60  QEKLREQVVKREELFIVSKLW-CTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKP 118

Query: 579 G--IYKLDFENRN---SSRIRKQTWATLVDLYHDHKIRALGVSNY 698
           G   + LD E+ N   S      TWA + +L  +  ++A+G+SN+
Sbjct: 119 GKEFFPLD-ESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNF 162


>UniRef50_Q03TW0 Cluster: Aldo/keto reductase of diketogulonate
           reductase family; n=1; Lactobacillus brevis ATCC
           367|Rep: Aldo/keto reductase of diketogulonate reductase
           family - Lactobacillus brevis (strain ATCC 367 / JCM
           1170)
          Length = 293

 Score = 91.1 bits (216), Expect = 7e-17
 Identities = 57/149 (38%), Positives = 80/149 (53%)
 Frame = +3

Query: 252 LNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPK 431
           +NNG ++P +GL  F++ +       +  AL AGYR  DTAA YGNE ++  A +    +
Sbjct: 16  MNNGHQIPQLGLGVFQVDNAEDTKNAIKWALAAGYRHIDTAAYYGNEQWVGEAIR----E 71

Query: 432 YKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLDFENRN 611
             + R  IF+ SKL   +  G   T+ AF  TL  LGLDY+DLYL+H P    LD     
Sbjct: 72  SDVPRDQIFVTSKLWN-SVRGYDETQAAFQETLDKLGLDYLDLYLIHWPAPGYLD----- 125

Query: 612 SSRIRKQTWATLVDLYHDHKIRALGVSNY 698
                  +W  + DLY   KI+ +GVSN+
Sbjct: 126 -------SWRAMEDLYKAGKIKNIGVSNF 147


>UniRef50_Q8CI22 Cluster: 2310005E10Rik protein; n=30;
           Tetrapoda|Rep: 2310005E10Rik protein - Mus musculus
           (Mouse)
          Length = 316

 Score = 90.6 bits (215), Expect = 9e-17
 Identities = 59/159 (37%), Positives = 89/159 (55%), Gaps = 9/159 (5%)
 Frame = +3

Query: 249 TLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLP 428
           TL  G +MP +GL T+K      V + V  A+ AGYR  D A +Y NE  +  A ++ + 
Sbjct: 6   TLLTGAKMPIVGLGTWKSPPA-KVREAVKVAIDAGYRHIDCAYVYQNESEVGEAIQEKIQ 64

Query: 429 KYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNP-----GIYKL 593
           +  +KR D+FI+SKL    +   ++ ++AF NTLS+L LDY+DLYL+H P     G   L
Sbjct: 65  EKAVKREDLFIVSKLW-STFFEKSLVKKAFQNTLSDLKLDYLDLYLIHWPQGFQSGNVFL 123

Query: 594 DFENRNSSRIRKQT----WATLVDLYHDHKIRALGVSNY 698
             +++ S    K T    W  + +L     ++ALGVSN+
Sbjct: 124 PTDDKGSILSSKYTFLDAWEAMEELVDQGLVKALGVSNF 162


>UniRef50_Q41E86 Cluster: 2,5-didehydrogluconate reductase; n=2;
           Bacteria|Rep: 2,5-didehydrogluconate reductase -
           Exiguobacterium sibiricum 255-15
          Length = 274

 Score = 90.6 bits (215), Expect = 9e-17
 Identities = 58/152 (38%), Positives = 79/152 (51%)
 Frame = +3

Query: 249 TLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLP 428
           TLNNG+ MP +G   FK+     V + V +AL+ GYR  DTA +Y NE  +  A K    
Sbjct: 5   TLNNGLVMPQLGYGVFKVPE-QEVYEAVREALRVGYRSIDTAMIYENEAGVGRALKDS-- 61

Query: 429 KYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLDFENR 608
              + R DIF+ +K+   + G    T  AF  +L  LG+DY+DLYL+H P          
Sbjct: 62  --GIPREDIFLTTKVWNKDQGYER-TLAAFETSLQKLGVDYVDLYLIHWP---------M 109

Query: 609 NSSRIRKQTWATLVDLYHDHKIRALGVSNYFI 704
               +   TW  L  LY D K +A+GVSN+ I
Sbjct: 110 PDEDLYMDTWRALEQLYRDGKAKAIGVSNFHI 141


>UniRef50_Q9VHX4 Cluster: CG2767-PA; n=4; Endopterygota|Rep:
           CG2767-PA - Drosophila melanogaster (Fruit fly)
          Length = 329

 Score = 90.6 bits (215), Expect = 9e-17
 Identities = 57/161 (35%), Positives = 84/161 (52%), Gaps = 11/161 (6%)
 Frame = +3

Query: 249 TLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLP 428
           T NNG +MP IG+ T++      +   +D AL+AGYR  DTA +YGNE  +    K+ L 
Sbjct: 8   TFNNGEKMPVIGIGTWQASD-EEIETAIDAALEAGYRHIDTAPVYGNEKAIGRVLKRWLD 66

Query: 429 KYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNP--------GI 584
             K+KR ++FI++K+ P +     V E     +L +L LDY+DLYLVH P        G 
Sbjct: 67  AGKVKREELFIVTKVPPVSNRPHEV-EPTIKKSLEDLQLDYVDLYLVHTPFTININEDGS 125

Query: 585 YKLDFENRNSSRI---RKQTWATLVDLYHDHKIRALGVSNY 698
           +KLD E      +       W  +  L      +++GVSN+
Sbjct: 126 FKLDKEGLMEVDVTTNHAAIWVAMEALVEKGLTKSIGVSNF 166


>UniRef50_Q03PG5 Cluster: Aldo/keto reductase of diketogulonate
           reductase family; n=1; Lactobacillus brevis ATCC
           367|Rep: Aldo/keto reductase of diketogulonate reductase
           family - Lactobacillus brevis (strain ATCC 367 / JCM
           1170)
          Length = 268

 Score = 89.8 bits (213), Expect = 2e-16
 Identities = 58/149 (38%), Positives = 78/149 (52%)
 Frame = +3

Query: 252 LNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPK 431
           L+NGV +P +G  T+ +     V   +  AL AGYR  D A +YGNE  +  A K     
Sbjct: 6   LSNGVTIPMLGFGTYLIDS-KDVPAAIKTALDAGYRHLDCAHIYGNEPAVGEAIKAS--- 61

Query: 432 YKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLDFENRN 611
             + R D+FI SK+   + G    T  AF  TLS+L LDY+DLYL+H P        N +
Sbjct: 62  -GIDRSDLFITSKVWNADQGYDK-TLAAFDQTLSDLQLDYLDLYLIHWP--------NED 111

Query: 612 SSRIRKQTWATLVDLYHDHKIRALGVSNY 698
              +   TW  L  LY   K+RA+GVSN+
Sbjct: 112 DFELTLDTWRVLETLYQQKKVRAIGVSNF 140


>UniRef50_Q16K66 Cluster: Aldo-keto reductase; n=2; Aedes
           aegypti|Rep: Aldo-keto reductase - Aedes aegypti
           (Yellowfever mosquito)
          Length = 303

 Score = 89.8 bits (213), Expect = 2e-16
 Identities = 55/155 (35%), Positives = 85/155 (54%), Gaps = 6/155 (3%)
 Frame = +3

Query: 252 LNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPK 431
           LNNG  +P IGL T+K+     V   +  A++ GYR+ DTA +Y NE  +  A +++  +
Sbjct: 4   LNNGHSIPPIGLGTYKITGSDGVA-AIKSAVEFGYRLIDTAFVYNNEQVVGQALREIFSQ 62

Query: 432 YK-LKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLDFENR 608
              + R D+FI+SKL P  +   AV E+    +L  LGLDY+DLYL+H P   +   +  
Sbjct: 63  GNDINREDVFIVSKLGPTFHRPEAV-EKGCRLSLERLGLDYVDLYLMHTPVAARDSGDGN 121

Query: 609 NSSRIRK-----QTWATLVDLYHDHKIRALGVSNY 698
           + S I       +TW  L +      +R++GVSN+
Sbjct: 122 DRSEIDDEVTPLETWKALEECQRKGLVRSIGVSNF 156


>UniRef50_Q5FK98 Cluster: Oxidoreductase; n=8; Lactobacillales|Rep:
           Oxidoreductase - Lactobacillus acidophilus
          Length = 285

 Score = 89.4 bits (212), Expect = 2e-16
 Identities = 53/155 (34%), Positives = 86/155 (55%)
 Frame = +3

Query: 234 LPQQFTLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAF 413
           L   +TLNNGV++P IG  T++        ++V  AL  GYR  DTA+ YGNE  +    
Sbjct: 6   LQDTYTLNNGVKIPIIGFGTWQTPDGEVAEESVLAALNCGYRHIDTASAYGNEDSVG--- 62

Query: 414 KKLLPKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKL 593
            + + K  + R ++FI +KL   ++ G   T++A   +L +L LDY+D+YL+H P    +
Sbjct: 63  -RAIQKSGINRHELFITTKLWNSDH-GYEKTKKAIDQSLLDLKLDYLDMYLIHWPNPSSM 120

Query: 594 DFENRNSSRIRKQTWATLVDLYHDHKIRALGVSNY 698
                + + I  ++W  + +     KIRA+GVSN+
Sbjct: 121 ---RDHWAEINAESWRAMEEAVRAGKIRAIGVSNF 152


>UniRef50_A2UAH0 Cluster: Aldo/keto reductase; n=1; Bacillus
           coagulans 36D1|Rep: Aldo/keto reductase - Bacillus
           coagulans 36D1
          Length = 273

 Score = 89.4 bits (212), Expect = 2e-16
 Identities = 53/157 (33%), Positives = 81/157 (51%)
 Frame = +3

Query: 234 LPQQFTLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAF 413
           L + F L NGV +P IGL T+++ +  T    V  ALK GYR  DTA  Y NE  +    
Sbjct: 4   LHETFVLENGVAIPKIGLGTWQVPNGETTYHAVSFALKNGYRHIDTAYAYHNEESVG--- 60

Query: 414 KKLLPKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKL 593
            K +    + R DIF+ SK LP          + F  T+ N GL+ +DLYL+H P  +  
Sbjct: 61  -KAVRDSGIDRRDIFVTSK-LPAEIKSYDKALKTFDETMGNFGLEQLDLYLIHAP--WPW 116

Query: 594 DFENRNSSRIRKQTWATLVDLYHDHKIRALGVSNYFI 704
             +  + ++   + W  + ++Y   + RA+GVSN+ +
Sbjct: 117 SEKGADYTKENIEVWKAMEEIYESGRCRAIGVSNFSV 153


>UniRef50_A6LZ55 Cluster: 2,5-didehydrogluconate reductase; n=1;
           Clostridium beijerinckii NCIMB 8052|Rep:
           2,5-didehydrogluconate reductase - Clostridium
           beijerinckii NCIMB 8052
          Length = 289

 Score = 88.6 bits (210), Expect = 4e-16
 Identities = 51/149 (34%), Positives = 81/149 (54%)
 Frame = +3

Query: 258 NGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPKYK 437
           NG+++P +G   +K+         V +A+K GYR FDTA +YGNE  L  A    + K +
Sbjct: 12  NGIKIPQVGFGVYKLNKGEDFETAVGEAIKIGYRHFDTAKIYGNEKDLGLA----IEKSQ 67

Query: 438 LKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLDFENRNSS 617
           + R + FI SK+   ++G  A T++AF  T   L ++Y+D+YL+H    Y L        
Sbjct: 68  IPREEFFITSKVWNTDHGYEA-TKKAFEQTCKKLNVEYLDMYLIHFASSYYL-------- 118

Query: 618 RIRKQTWATLVDLYHDHKIRALGVSNYFI 704
               +TW  + +LY   KI+ +GV+N+ I
Sbjct: 119 ----ETWHAMEELYLQGKIKVIGVANFQI 143


>UniRef50_Q09632 Cluster: Probable oxidoreductase ZK1290.5; n=2;
           Caenorhabditis|Rep: Probable oxidoreductase ZK1290.5 -
           Caenorhabditis elegans
          Length = 321

 Score = 88.6 bits (210), Expect = 4e-16
 Identities = 56/153 (36%), Positives = 80/153 (52%), Gaps = 2/153 (1%)
 Frame = +3

Query: 252 LNNGVEMPAIGLDTFKMGHFY--TVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLL 425
           L+N VEMP IGL T   G +Y   VL ++    K GYR+ DTA  YG E  L  A K   
Sbjct: 7   LSNNVEMPLIGLGTTHSGGYYHDAVLHSIK---KCGYRLIDTAKRYGVEKQLGIAVKNC- 62

Query: 426 PKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLDFEN 605
               + R ++F+ +KL P + G       AF  +   L  DY+D+Y++H P   +L    
Sbjct: 63  ---SVPREEMFLSTKLWPVDCGDEVYN--AFQTSCEKLQTDYLDMYMIHMP---QLPDWI 114

Query: 606 RNSSRIRKQTWATLVDLYHDHKIRALGVSNYFI 704
            N    +++TW  +  LY D  +R++GVSNY I
Sbjct: 115 VNQKETKEKTWRQMELLYEDEHVRSIGVSNYSI 147


>UniRef50_Q03XK0 Cluster: Aldo/keto reductase of diketogulonate
           reductase family; n=3; Lactobacillales|Rep: Aldo/keto
           reductase of diketogulonate reductase family -
           Leuconostoc mesenteroides subsp. mesenteroides (strain
           ATCC 8293 /NCDO 523)
          Length = 292

 Score = 88.2 bits (209), Expect = 5e-16
 Identities = 53/152 (34%), Positives = 80/152 (52%)
 Frame = +3

Query: 249 TLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLP 428
           TL +G+EMP +G   F++       Q V DA+K GYR+ DTAA YGNE  +  A  + + 
Sbjct: 5   TLASGIEMPLLGFGVFQVQEKGAAKQAVLDAIKTGYRLIDTAASYGNEREVGEAILEAIN 64

Query: 429 KYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLDFENR 608
           +  +KR ++F+ SK+   +      T  A  ++L  L LDY+DLYL+H P  Y   F   
Sbjct: 65  QGIVKREELFVTSKMWVQDVSAQQAT-AAIQSSLQRLNLDYLDLYLIHQP--YNDVF--- 118

Query: 609 NSSRIRKQTWATLVDLYHDHKIRALGVSNYFI 704
                    W  +   Y   +++A+GVSN+ I
Sbjct: 119 -------GAWRAMESAYRSGQLKAIGVSNFDI 143


>UniRef50_Q7NB44 Cluster: ARA1; n=3; Firmicutes|Rep: ARA1 -
           Mycoplasma gallisepticum
          Length = 289

 Score = 87.8 bits (208), Expect = 7e-16
 Identities = 53/151 (35%), Positives = 87/151 (57%)
 Frame = +3

Query: 252 LNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPK 431
           L N  +MP+IG  T+K+      ++ V  AL+ GYR  D A +Y N++ ++   K     
Sbjct: 16  LANNYKMPSIGFGTYKLEDGKQTVEAVKTALEVGYRHLDCAEIYENQLSVSQGIK----L 71

Query: 432 YKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLDFENRN 611
             + R +IFI SK+   + G  + T++AFH  L +L L+Y+DL L+H P I K  F++ N
Sbjct: 72  SGVNRKEIFITSKIWNDDKGYES-TKKAFHKILKDLDLEYLDLLLIHWP-IGK-GFKD-N 127

Query: 612 SSRIRKQTWATLVDLYHDHKIRALGVSNYFI 704
              +  QTW  + + Y + KI+A+G+SN+ +
Sbjct: 128 WQEVNAQTWKAMEEFYLEGKIKAIGLSNFLV 158


>UniRef50_Q61U89 Cluster: Putative uncharacterized protein CBG05425;
           n=1; Caenorhabditis briggsae|Rep: Putative
           uncharacterized protein CBG05425 - Caenorhabditis
           briggsae
          Length = 319

 Score = 87.8 bits (208), Expect = 7e-16
 Identities = 46/114 (40%), Positives = 63/114 (55%), Gaps = 1/114 (0%)
 Frame = +3

Query: 318 VLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPKYKLKRGDIFIISKLLPC-NYGG 494
           +L  VD A++ GYR FDTA  Y NE  L  A K LLPKYKL   DIF+ +K+ P  N   
Sbjct: 79  LLHAVDKAVEVGYRSFDTAKYYENEGELGEALKILLPKYKLSTEDIFLTTKIFPVENAAS 138

Query: 495 GAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLDFENRNSSRIRKQTWATLVDL 656
           G + ++    +L  L  +Y+DL LVH P  +  D ++  +   RK+ W  L  L
Sbjct: 139 GELIKKDIEESLKLLNREYLDLVLVHYPRPFTTDDKDERNKIYRKEAWLALESL 192


>UniRef50_A0JRJ6 Cluster: Aldo/keto reductase; n=2;
           Micrococcineae|Rep: Aldo/keto reductase - Arthrobacter
           sp. (strain FB24)
          Length = 281

 Score = 87.4 bits (207), Expect = 9e-16
 Identities = 57/152 (37%), Positives = 82/152 (53%)
 Frame = +3

Query: 243 QFTLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKL 422
           Q TLNNGV++P +G   F++    T  + V+DAL+AGYR  DTAA Y NE  +  A    
Sbjct: 11  QLTLNNGVKIPQLGFGVFQVPPEETQ-RIVEDALEAGYRHIDTAAAYRNEAGVGAA---- 65

Query: 423 LPKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLDFE 602
           +    + R DIFI +KL     G       AF N+   LG++++DLYL+H P        
Sbjct: 66  ISASGIPREDIFITTKLRNGEQGN---AHEAFQNSRKALGVEFVDLYLIHWP-------- 114

Query: 603 NRNSSRIRKQTWATLVDLYHDHKIRALGVSNY 698
              S  +  + W  +  LY + +IRA+GVSN+
Sbjct: 115 -VPSQGLYTEAWKAMEKLYANSQIRAIGVSNF 145


>UniRef50_Q24C22 Cluster: Oxidoreductase, aldo/keto reductase family
           protein; n=4; Oligohymenophorea|Rep: Oxidoreductase,
           aldo/keto reductase family protein - Tetrahymena
           thermophila SB210
          Length = 297

 Score = 87.4 bits (207), Expect = 9e-16
 Identities = 51/148 (34%), Positives = 82/148 (55%)
 Frame = +3

Query: 261 GVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPKYKL 440
           G  +P IG  T+++     ++  V +ALK GY   DTA++Y NE  +        P Y +
Sbjct: 21  GGSIPQIGYGTYELRQNDCIIG-VTEALKIGYTHIDTASVYRNEQDIAKVIHN--PAYGI 77

Query: 441 KRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLDFENRNSSR 620
           KR D+FI SK+ P   G     ++A  + L+ L + Y+D  L+H PG+ KL   +  +++
Sbjct: 78  KREDLFITSKISPGEQGYEQA-KKAVQDMLTRLNIKYLDCVLIHWPGVSKLPPNDPKNAQ 136

Query: 621 IRKQTWATLVDLYHDHKIRALGVSNYFI 704
           IR +TW  L++L     I+ +GVSN+ I
Sbjct: 137 IRLETWKALIELRKAGVIKHIGVSNFNI 164


>UniRef50_P38715 Cluster: NADPH-dependent aldose reductase GRE3;
           n=39; cellular organisms|Rep: NADPH-dependent aldose
           reductase GRE3 - Saccharomyces cerevisiae (Baker's
           yeast)
          Length = 327

 Score = 87.0 bits (206), Expect = 1e-15
 Identities = 48/121 (39%), Positives = 73/121 (60%), Gaps = 1/121 (0%)
 Frame = +3

Query: 249 TLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLP 428
           TLNNG++MP +GL  +K+       Q + +A+K GYR+FD A  YGNE  +    +K + 
Sbjct: 6   TLNNGLKMPLVGLGCWKIDKKVCANQ-IYEAIKLGYRLFDGACDYGNEKEVGEGIRKAIS 64

Query: 429 KYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYK-LDFEN 605
           +  + R DIF++SKL   N+      + A   TLS++GLDY+DLY +H P  +K + FE 
Sbjct: 65  EGLVSRKDIFVVSKLWN-NFHHPDHVKLALKKTLSDMGLDYLDLYYIHFPIAFKYVPFEE 123

Query: 606 R 608
           +
Sbjct: 124 K 124


>UniRef50_Q2LZ66 Cluster: GA19341-PA; n=2; Endopterygota|Rep:
           GA19341-PA - Drosophila pseudoobscura (Fruit fly)
          Length = 315

 Score = 86.2 bits (204), Expect = 2e-15
 Identities = 56/161 (34%), Positives = 83/161 (51%), Gaps = 10/161 (6%)
 Frame = +3

Query: 246 FTLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLL 425
           F L++G  MP +GL T++      V Q V DA+  GYR FD A +YGNE+++  A ++ +
Sbjct: 6   FLLSSGRNMPMVGLGTWRSPP-EVVAQAVKDAIDIGYRHFDCAHIYGNELHVGVAIREKI 64

Query: 426 PKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKL---- 593
            +  + R ++FI SKL    +    +   A   +L NLG+DY+DLYL+H P  YK     
Sbjct: 65  QEGLVTRDELFITSKLWN-TFHKPELVRAACETSLRNLGIDYLDLYLMHWPMAYKSGDNL 123

Query: 594 -----DFENRNSSRI-RKQTWATLVDLYHDHKIRALGVSNY 698
                D        I    TW  + DL     + A+GVSN+
Sbjct: 124 YPTCPDTGKAVFEDIDYLDTWKAMEDLVDSGLVNAIGVSNF 164


>UniRef50_Q22352 Cluster: Putative uncharacterized protein T08H10.1;
           n=2; Caenorhabditis|Rep: Putative uncharacterized
           protein T08H10.1 - Caenorhabditis elegans
          Length = 333

 Score = 86.2 bits (204), Expect = 2e-15
 Identities = 57/159 (35%), Positives = 79/159 (49%), Gaps = 10/159 (6%)
 Frame = +3

Query: 252 LNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPK 431
           LN G ++P  GL T+++     +   +  AL AGYR+ DTA LY NE  +     + +  
Sbjct: 8   LNTGAQLPLFGLGTWQVKDEAELTVALRAALDAGYRLIDTAHLYQNEHIIGKVLHEYISS 67

Query: 432 YKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLD----- 596
            KLKR DIF+ SKL P          +   + L  L L+YIDLYL+H P  +K       
Sbjct: 68  GKLKREDIFVTSKL-PFTAHAPEDVPKCVESQLKALQLEYIDLYLIHCPFPFKHQEGSFA 126

Query: 597 --FENRN---SSRIRKQTWATLVDLYHDHKIRALGVSNY 698
              EN     +      TW  L  LY + K++ALGVSN+
Sbjct: 127 PLMENGELAVTEIAHIDTWRALEKLYKEGKLKALGVSNF 165


>UniRef50_UPI0000588153 Cluster: PREDICTED: hypothetical protein;
           n=1; Strongylocentrotus purpuratus|Rep: PREDICTED:
           hypothetical protein - Strongylocentrotus purpuratus
          Length = 333

 Score = 85.8 bits (203), Expect = 3e-15
 Identities = 57/161 (35%), Positives = 87/161 (54%), Gaps = 11/161 (6%)
 Frame = +3

Query: 249 TLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLP 428
           TL +G  MP +GL T+K+     V   +  A+ AGYR FD A +YGNE  +  A ++ + 
Sbjct: 6   TLPSGHAMPLVGLGTWKL-KADEVAGAIGAAVDAGYRHFDCALIYGNEKEVGVALREAMQ 64

Query: 429 KYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNP-GIYKLD--- 596
           +  LKR D+FI +K+    +    V E  F+ +L++L LDYIDLY++H P G   L    
Sbjct: 65  RLGLKREDVFITTKVWNTFHAKEDVAE-CFNRSLTDLQLDYIDLYIMHWPLGFQNLGPTV 123

Query: 597 -FENRNSSRI------RKQTWATLVDLYHDHKIRALGVSNY 698
            F    +  I        +TW+ + DL    K ++LG+SN+
Sbjct: 124 MFPRTETGDIVYSDVHYLETWSAMEDLVKTGKCKSLGLSNF 164


>UniRef50_UPI000065D0BD Cluster: Homolog of Homo sapiens "AKR1B1
           protein.; n=1; Takifugu rubripes|Rep: Homolog of Homo
           sapiens "AKR1B1 protein. - Takifugu rubripes
          Length = 330

 Score = 85.8 bits (203), Expect = 3e-15
 Identities = 46/110 (41%), Positives = 66/110 (60%)
 Frame = +3

Query: 249 TLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLP 428
           TLN G  MP +GL T+K G   T  + V  A+ AGYR  DTA +Y NE  +    + ++ 
Sbjct: 6   TLNTGALMPVLGLGTWKSGKGVTT-EAVKVAIGAGYRHIDTAYVYENETEVGAGVQAMID 64

Query: 429 KYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNP 578
           +  +KR ++FI+SKL  C +   ++   A   TLS+L LDY+DLYL+H P
Sbjct: 65  QGVVKREELFIVSKLW-CTFHTPSLVRGACEKTLSSLNLDYVDLYLMHFP 113


>UniRef50_P22045 Cluster: Probable reductase; n=101; cellular
           organisms|Rep: Probable reductase - Leishmania major
          Length = 284

 Score = 85.8 bits (203), Expect = 3e-15
 Identities = 57/152 (37%), Positives = 79/152 (51%)
 Frame = +3

Query: 249 TLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLP 428
           TL+NGV+MP  GL  ++          V+ AL AGYR  DTAA+Y NE  +       L 
Sbjct: 10  TLSNGVKMPQFGLGVWQSPAGEVTENAVNWALCAGYRHIDTAAIYKNEESVGAG----LR 65

Query: 429 KYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLDFENR 608
              + R D+FI +KL     G  + T  AF  +   LG+DYIDLYL+H P     D  ++
Sbjct: 66  ASGVPREDVFITTKLWNTEQGYES-TLAAFEESRQKLGVDYIDLYLIHWP--RGKDILSK 122

Query: 609 NSSRIRKQTWATLVDLYHDHKIRALGVSNYFI 704
              +    +W     LY + K+RA+GVSN+ I
Sbjct: 123 EGKKY-LDSWRAFEQLYKEKKVRAIGVSNFHI 153


>UniRef50_Q02198 Cluster: Morphine 6-dehydrogenase; n=5;
           Bacteria|Rep: Morphine 6-dehydrogenase - Pseudomonas
           putida
          Length = 296

 Score = 85.8 bits (203), Expect = 3e-15
 Identities = 53/149 (35%), Positives = 79/149 (53%)
 Frame = +3

Query: 252 LNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPK 431
           LNNGV+MPA+GL  F      T    +  A+ +GYR+ DTA  Y NE  +    +     
Sbjct: 10  LNNGVKMPALGLGVFAASAEETA-SAIASAISSGYRLIDTARSYNNEAQVGEGIRNS--- 65

Query: 432 YKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLDFENRN 611
             + R ++F+ +KL  C+YG      RAF  +L  LGLDY+DLYL+H P       ++ N
Sbjct: 66  -GVDRAEMFVTTKLFNCDYGYERAL-RAFDESLGRLGLDYVDLYLLHWP------TKDWN 117

Query: 612 SSRIRKQTWATLVDLYHDHKIRALGVSNY 698
           ++    Q+W     +  D + RA+GV N+
Sbjct: 118 AT---IQSWKAAEKILGDGRARAIGVCNF 143


>UniRef50_Q55FL3 Cluster: Aldo-keto reductase; n=2; Dictyostelium
           discoideum AX4|Rep: Aldo-keto reductase - Dictyostelium
           discoideum AX4
          Length = 321

 Score = 85.0 bits (201), Expect = 5e-15
 Identities = 54/165 (32%), Positives = 89/165 (53%), Gaps = 14/165 (8%)
 Frame = +3

Query: 246 FTLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLL 425
           F LN+G ++P+IGL T+   +   V   +++ALK GYR  D AA YGNE  +  + K++ 
Sbjct: 17  FKLNDGNQIPSIGLGTYYSENPGEVGDAINNALKNGYRHIDGAAFYGNEKVIGNSLKEIF 76

Query: 426 PKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVH--------NP- 578
            + ++KR DIF  SKL    +    V +     T+ +LG+ Y+DLYL+H        NP 
Sbjct: 77  KEGEIKREDIFYTSKLWNSCHNSNLVVKHCV-KTIEDLGIGYLDLYLIHWPIAFENSNPL 135

Query: 579 GIYKLDFENRNSSRIR-----KQTWATLVDLYHDHKIRALGVSNY 698
           G+      ++N + I      ++TW  +  L     ++++GVSN+
Sbjct: 136 GLTIEPLRDQNGNPIIAPVSIRETWQEMEKLVELGLVKSIGVSNF 180


>UniRef50_Q7VG53 Cluster: Aldo-keto reductase; n=28; Bacteria|Rep:
           Aldo-keto reductase - Helicobacter hepaticus
          Length = 292

 Score = 84.6 bits (200), Expect = 6e-15
 Identities = 54/156 (34%), Positives = 83/156 (53%)
 Frame = +3

Query: 231 ILPQQFTLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFA 410
           IL + FTLNNG ++P +GL T+++     V   V +A K GYR  DTA  YGNE  +  A
Sbjct: 10  ILNEFFTLNNGNKIPKLGLGTWRIDD-NVVEAAVREAFKVGYRHIDTAQAYGNERGVGEA 68

Query: 411 FKKLLPKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYK 590
            +    K K+KR ++FI SK +   Y        +   +L  + LD+IDL L+H+P  + 
Sbjct: 69  VR----KSKIKREELFITSK-IRAEYKDYKSASASIDTSLKTMKLDFIDLMLIHSPQPWN 123

Query: 591 LDFENRNSSRIRKQTWATLVDLYHDHKIRALGVSNY 698
             F   +  +   + +  L D     K+R++GVSN+
Sbjct: 124 -SFRKGDYFKENVEVYNALEDAQKAGKVRSIGVSNF 158


>UniRef50_P38115 Cluster: D-arabinose dehydrogenase [NAD(P)+] heavy
           chain; n=3; Saccharomycetaceae|Rep: D-arabinose
           dehydrogenase [NAD(P)+] heavy chain - Saccharomyces
           cerevisiae (Baker's yeast)
          Length = 344

 Score = 84.6 bits (200), Expect = 6e-15
 Identities = 60/175 (34%), Positives = 90/175 (51%), Gaps = 22/175 (12%)
 Frame = +3

Query: 246 FTLNNGVEMPAIGLDTFKMGH-FYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKL 422
           F+LNNGV +PA+GL T           Q V  A+KAGYR  DTA  Y  E ++  A K+L
Sbjct: 25  FSLNNGVRIPALGLGTANPHEKLAETKQAVKAAIKAGYRHIDTAWAYETEPFVGEAIKEL 84

Query: 423 LPKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNP-------- 578
           L    +KR D+FI +K+ P  +      +R+ + +L  LGL+Y+DL L H P        
Sbjct: 85  LEDGSIKREDLFITTKVWPVLWD---EVDRSLNESLKALGLEYVDLLLQHWPLCFEKIKD 141

Query: 579 -----GIYKLDFENRNSSRIRK-----QTWATLVDLY---HDHKIRALGVSNYFI 704
                G+ K   ++   +         +T+  L  +Y   +DH++RA+GVSN+ I
Sbjct: 142 PKGISGLVKTPVDDSGKTMYAADGDYLETYKQLEKIYLDPNDHRVRAIGVSNFSI 196


>UniRef50_Q8WRT0 Cluster: 3-dehydrecdysone 3b-reductase; n=1;
           Trichoplusia ni|Rep: 3-dehydrecdysone 3b-reductase -
           Trichoplusia ni (Cabbage looper)
          Length = 308

 Score = 84.2 bits (199), Expect = 8e-15
 Identities = 53/150 (35%), Positives = 81/150 (54%), Gaps = 1/150 (0%)
 Frame = +3

Query: 252 LNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPK 431
           LN+G  +P++ L TF  G    V Q V  A++AGYR  DTAALYGNE  +       + +
Sbjct: 29  LNDGNAIPSLALGTFGFGDIPKVRQAVLWAIQAGYRHIDTAALYGNEEEVGKGIADAIQQ 88

Query: 432 YKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLDFENRN 611
             +KR ++F+ +KL    +G   V   A   +L+ LGL Y+DLYL+H+P   +   EN +
Sbjct: 89  GLVKREELFVTTKLWNDKHGRHQVVP-ALRESLTKLGLSYVDLYLIHSP---EATNENGD 144

Query: 612 SSRIR-KQTWATLVDLYHDHKIRALGVSNY 698
              I    TW  + +       +++GVSN+
Sbjct: 145 PVDIDVLNTWNGMEEAKKLGLAKSIGVSNF 174


>UniRef50_Q54B70 Cluster: Aldehyde reductase; n=2; Dictyostelium
           discoideum|Rep: Aldehyde reductase - Dictyostelium
           discoideum AX4
          Length = 297

 Score = 84.2 bits (199), Expect = 8e-15
 Identities = 58/162 (35%), Positives = 89/162 (54%), Gaps = 7/162 (4%)
 Frame = +3

Query: 246 FTLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAF-KKL 422
           F L++G ++P +G  T+K      V + V+ AL AGYR  D AA+Y NE  +  AF KK 
Sbjct: 5   FKLSSGHKIPLVGFGTWK-AETTLVGKAVEVALDAGYRHIDCAAVYLNEKEVGEAFTKKF 63

Query: 423 LPKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKL--- 593
             +  +KR D+FI SKL    +    V   A   TLS+LGL Y+DLYLVH P  ++    
Sbjct: 64  TTEATVKREDVFITSKLWNTFHKKEHVRP-ALERTLSDLGLQYLDLYLVHWPVAFEYTSN 122

Query: 594 DFENRNSSR---IRKQTWATLVDLYHDHKIRALGVSNYFIWG 710
           D +   S++     ++TW  +  L     ++++G+SN+ + G
Sbjct: 123 DIQTSGSTQEFVSIRETWEEMEKLVDAGLVKSIGLSNFNVQG 164


>UniRef50_Q9VTL0 Cluster: CG6083-PA; n=4; Diptera|Rep: CG6083-PA -
           Drosophila melanogaster (Fruit fly)
          Length = 322

 Score = 83.8 bits (198), Expect = 1e-14
 Identities = 54/162 (33%), Positives = 84/162 (51%), Gaps = 11/162 (6%)
 Frame = +3

Query: 246 FTLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLL 425
           F L+NG  MP +GL T++      V Q V DA+  GYR FD A +YGNE  +  A ++ +
Sbjct: 6   FLLSNGKNMPMLGLGTWRSPP-EVVTQAVKDAIDIGYRHFDCAHIYGNEAQVGAALREKM 64

Query: 426 PKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLDFEN 605
            +  + R ++FI SKL   ++    V   A   ++ NLG+ Y++LYL+H P  YK   +N
Sbjct: 65  DEGVVTRDELFITSKLWNTHHKPDLV-RPACETSIRNLGVKYLNLYLMHWPMAYKSGSDN 123

Query: 606 -------RNSSRIRK----QTWATLVDLYHDHKIRALGVSNY 698
                   N +         TW  + +L  +   +A+GVSN+
Sbjct: 124 LYPTCPDTNKAAFEDIDYVDTWRAMENLVDEGLCQAIGVSNF 165


>UniRef50_A5E082 Cluster: GCY protein; n=4; Saccharomycetales|Rep:
           GCY protein - Lodderomyces elongisporus (Yeast)
           (Saccharomyces elongisporus)
          Length = 295

 Score = 83.8 bits (198), Expect = 1e-14
 Identities = 53/152 (34%), Positives = 78/152 (51%), Gaps = 1/152 (0%)
 Frame = +3

Query: 246 FTLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLL 425
           +TLNNG+++PAIGL T+         +    ALK GY+  DTAA YGNE  +     + +
Sbjct: 12  YTLNNGLKIPAIGLGTWLADEEDAAYKATLTALKNGYKHIDTAAAYGNEDQVG----RAI 67

Query: 426 PKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLDFEN 605
               + R +IF+ +KL    +      E A   +L  LGL+Y+DLYL+H P       E 
Sbjct: 68  ADSGVSRDEIFVTTKLWNDQHKD---PEGALDESLKKLGLEYVDLYLIHWPLSVDPKTEK 124

Query: 606 RNSSRIRKQTWATLVDLYHD-HKIRALGVSNY 698
                    TW  L  +Y +  K++A+GVSN+
Sbjct: 125 PYDDYDFVDTWRNLQKIYKEGKKVKAIGVSNF 156


>UniRef50_A3LTU8 Cluster: D-arabinose dehydrogenase; n=5;
           Saccharomycetales|Rep: D-arabinose dehydrogenase -
           Pichia stipitis (Yeast)
          Length = 326

 Score = 83.8 bits (198), Expect = 1e-14
 Identities = 59/172 (34%), Positives = 90/172 (52%), Gaps = 19/172 (11%)
 Frame = +3

Query: 246 FTLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLL 425
           F L+NG  +PA+GL T      + + + V  A+KAGYR  DTA  YG E Y+  A K+L 
Sbjct: 10  FVLSNGKTIPALGLGTVPPEDPHELKEQVITAVKAGYRHIDTAWYYGTEEYIGQALKQLF 69

Query: 426 PKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLDFEN 605
            +  +KR D+FI +K+ P  +      E++   +L++LGLDY+DL+L H P +   D EN
Sbjct: 70  EEGIVKREDLFITTKVWPSFWRN---PEKSLDKSLADLGLDYVDLFLQHWPVVLHGD-EN 125

Query: 606 RNSSRIRKQTWATL-----------VDLYHD--------HKIRALGVSNYFI 704
               + R +    +           +D YH          K++++GVSNY I
Sbjct: 126 GLPPQPRDKDGKLIYDDDPVSGIKYIDAYHSLEDIMDNTSKVKSIGVSNYSI 177


>UniRef50_UPI00006CA3CB Cluster: oxidoreductase, aldo/keto reductase
           family protein; n=3; Tetrahymena thermophila SB210|Rep:
           oxidoreductase, aldo/keto reductase family protein -
           Tetrahymena thermophila SB210
          Length = 299

 Score = 83.4 bits (197), Expect = 1e-14
 Identities = 50/151 (33%), Positives = 75/151 (49%), Gaps = 1/151 (0%)
 Frame = +3

Query: 249 TLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLP 428
           TL+NG +MPA GL + ++     V   +  AL  GYR  DTA +Y NE ++  A K +  
Sbjct: 11  TLSNGQKMPAFGLGSSRVQSVEEVTNLIRKALDVGYRHIDTAQMYENEQFIGAALKTIFG 70

Query: 429 KYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNP-GIYKLDFEN 605
           + K KR DIF+++K        G          L  L +DY+DL L+H P      D++ 
Sbjct: 71  EGKYKREDIFLVTKQASIK---GVSCLEIMKEQLQKLQVDYVDLLLIHVPLAAPSDDYQQ 127

Query: 606 RNSSRIRKQTWATLVDLYHDHKIRALGVSNY 698
            N   +  Q WA   +++     + LGVSN+
Sbjct: 128 WNHKPVH-QIWAEFEEIHSLGLAKGLGVSNF 157


>UniRef50_Q568D7 Cluster: Zgc:110366; n=7; Euteleostomi|Rep:
           Zgc:110366 - Danio rerio (Zebrafish) (Brachydanio rerio)
          Length = 289

 Score = 83.4 bits (197), Expect = 1e-14
 Identities = 52/151 (34%), Positives = 85/151 (56%)
 Frame = +3

Query: 252 LNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPK 431
           L+NG+ +P +GL T   G  Y+    +    + G R  DTA  YG E  L     K + +
Sbjct: 18  LHNGLNIPILGLGTSHYGG-YSHEAVLYALQECGIRHIDTAKRYGCEEALG----KAVTE 72

Query: 432 YKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLDFENRN 611
             ++R ++++ +KL P +YG  + T++A  ++ + LG+DY+DLYL+H P         R+
Sbjct: 73  SGVQREELWVTTKLWPGDYGYQS-TKQACRDSRARLGVDYLDLYLMHWPDSM---VPGRS 128

Query: 612 SSRIRKQTWATLVDLYHDHKIRALGVSNYFI 704
           S  +R +TW  L +LY +   RA+GVSN+ I
Sbjct: 129 SQEVRLETWRALEELYDEGLCRAIGVSNFLI 159


>UniRef50_A3JU52 Cluster: 2,5-diketo-D-gluconic acid reductase A;
           n=1; Rhodobacterales bacterium HTCC2150|Rep:
           2,5-diketo-D-gluconic acid reductase A - Rhodobacterales
           bacterium HTCC2150
          Length = 334

 Score = 83.4 bits (197), Expect = 1e-14
 Identities = 56/157 (35%), Positives = 82/157 (52%), Gaps = 6/157 (3%)
 Frame = +3

Query: 246 FTLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLL 425
           FTLN    +PA+G  T+ + +      T+  A++AGYR  DTA+ Y NE  +    K  L
Sbjct: 40  FTLNTTTTIPAVGFGTYLISND-DAKSTISAAIQAGYRHIDTASGYQNEKTVGAGIKAGL 98

Query: 426 PKYKLKRGDIFIISKLLPCNYGGG------AVTERAFHNTLSNLGLDYIDLYLVHNPGIY 587
               + R D+F+ +KL P N   G      A T      +L+ LGLDY+DLYL+H P  Y
Sbjct: 99  QSAGITRKDLFVTAKLWPGNPAWGDAPKTKAQTLDECDASLARLGLDYVDLYLIHAP--Y 156

Query: 588 KLDFENRNSSRIRKQTWATLVDLYHDHKIRALGVSNY 698
             D        +R + W  L++L  + K R++GVSN+
Sbjct: 157 GGD--------MRLEQWRALLELQANGKARSIGVSNF 185


>UniRef50_Q2UGR1 Cluster: Aldo/keto reductase family proteins; n=2;
           Ascomycota|Rep: Aldo/keto reductase family proteins -
           Aspergillus oryzae
          Length = 323

 Score = 83.4 bits (197), Expect = 1e-14
 Identities = 62/166 (37%), Positives = 86/166 (51%), Gaps = 11/166 (6%)
 Frame = +3

Query: 234 LPQQFTLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAF 413
           L + F LN+G  +PAIGL T+ +   + V   V+ AL+AGYR  D AA Y NE  +   +
Sbjct: 3   LGRTFKLNSGYNIPAIGLGTW-LSKPHEVENAVEAALRAGYRHIDAAACYQNENEVGNGW 61

Query: 414 KKLLPKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKL 593
           KK      + R  IFI SKL   ++    V E A + TL +L  DY+DLYL+H P  ++ 
Sbjct: 62  KKS----GVPRDQIFITSKLWNTHHHPEHV-EEAVNKTLKDLQTDYLDLYLIHWPVAFEH 116

Query: 594 DFENRN-----SSRIR------KQTWATLVDLYHDHKIRALGVSNY 698
             E        + R R        TWA L  L    KIR++G+SN+
Sbjct: 117 TNETLTPIDPVTKRFRLANVPIADTWAALEKLVEAKKIRSIGISNF 162


>UniRef50_A7PNI3 Cluster: Chromosome chr1 scaffold_22, whole genome
           shotgun sequence; n=2; Vitis vinifera|Rep: Chromosome
           chr1 scaffold_22, whole genome shotgun sequence - Vitis
           vinifera (Grape)
          Length = 360

 Score = 82.6 bits (195), Expect = 2e-14
 Identities = 58/161 (36%), Positives = 79/161 (49%), Gaps = 10/161 (6%)
 Frame = +3

Query: 246 FTLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLL 425
           F LN   ++PAIGL T++ G    V + V  AL  GYR  D A LYGNEV +  A  +  
Sbjct: 12  FLLNTKAKIPAIGLGTWQSGGDLCV-EAVKRALSEGYRQIDCAHLYGNEVEVGEALAEAF 70

Query: 426 PKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKL---- 593
               LKR D+F+ SKL  C        E +   +L NLG+ Y+DLYL+H P I       
Sbjct: 71  -NGSLKREDVFLTSKLY-CTMNSLNKIENSVRVSLKNLGVTYLDLYLMHWPDITAFGDAT 128

Query: 594 ------DFENRNSSRIRKQTWATLVDLYHDHKIRALGVSNY 698
                   ++R      K+ W  +  L     +RA+GVSN+
Sbjct: 129 DPPSNSGNDHRQFLNRLKKAWKAMEGLIELGLVRAIGVSNF 169


>UniRef50_Q0IBY6 Cluster: Alcohol dehydrogenase; n=2;
           Chroococcales|Rep: Alcohol dehydrogenase - Synechococcus
           sp. (strain CC9311)
          Length = 336

 Score = 82.2 bits (194), Expect = 3e-14
 Identities = 46/122 (37%), Positives = 73/122 (59%), Gaps = 2/122 (1%)
 Frame = +3

Query: 219 DFKYILP--QQFTLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNE 392
           + K ++P  Q  +L+NG  MP +GL T K      V ++V +A+K GYR  D A++YGNE
Sbjct: 11  NIKDVIPTMQYASLSNGDRMPLLGLGTGK-SESRQVYKSVREAIKIGYRHIDCASIYGNE 69

Query: 393 VYLNFAFKKLLPKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVH 572
             +  A +  +  +++ R +++I SKL    +G   V E A   +L NLG+DY++LYL+H
Sbjct: 70  EEVGDAIRDAIQNHEITRSELWITSKLWSNCHGKNHV-EAALSQSLQNLGVDYLNLYLIH 128

Query: 573 NP 578
            P
Sbjct: 129 WP 130


>UniRef50_Q6TY50 Cluster: Reductase 2; n=10; Magnoliophyta|Rep:
           Reductase 2 - Hydrangea macrophylla (Bigleaf hydrangea)
          Length = 321

 Score = 82.2 bits (194), Expect = 3e-14
 Identities = 58/166 (34%), Positives = 86/166 (51%), Gaps = 9/166 (5%)
 Frame = +3

Query: 228 YILPQQFTLNNGVEMPAIGLDTFKMGHF--YTVLQTVDDALKAGYRMFDTAALYGNEVYL 401
           + +P+    + G +MP +GL T         TV + V +ALK GYR FDTAALY +E  L
Sbjct: 3   FTIPEVPLSSGGRKMPVLGLGTAADPPVDPETVRKAVTEALKLGYRHFDTAALYNSEQPL 62

Query: 402 NFAFKKLLPKYKLK-RGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVH-- 572
             A  + L +  +K R ++FI SKL  C+       E A   TL NL L+YID+YL+H  
Sbjct: 63  GDAIAEALGEGLIKSRDELFITSKLW-CSDAHRENVEPALQKTLKNLKLEYIDMYLIHWP 121

Query: 573 ---NPGIYKLDFENRNSSRI-RKQTWATLVDLYHDHKIRALGVSNY 698
               PG Y+   +  +  ++  K  W  + +       +A+GVSN+
Sbjct: 122 VSSKPGNYEYPIKKEDFLQMDYKSVWEAMEECQKLGLTKAIGVSNF 167


>UniRef50_Q7PM68 Cluster: ENSANGP00000014386; n=1; Anopheles gambiae
           str. PEST|Rep: ENSANGP00000014386 - Anopheles gambiae
           str. PEST
          Length = 310

 Score = 82.2 bits (194), Expect = 3e-14
 Identities = 53/157 (33%), Positives = 81/157 (51%), Gaps = 10/157 (6%)
 Frame = +3

Query: 258 NGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFK-KLLPKY 434
           + + +P IGL T+ +       + +  A+  GYRMFDTA  YGNE  +  A + K+    
Sbjct: 13  HSIALPTIGLGTYSILGA-DGKEAIRTAIDVGYRMFDTAVAYGNEAIVGEAIREKIRECN 71

Query: 435 KLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLDFE-NRN 611
            L R D FIISKL   +Y    + E+    TL  LG+DY+DLYL+H P   + + +  RN
Sbjct: 72  NLTRDDFFIISKLSG-SYHRQDLVEKCCRMTLDRLGMDYVDLYLMHTPVALQSEKKCARN 130

Query: 612 SSRIR--------KQTWATLVDLYHDHKIRALGVSNY 698
            +++          + W  L   Y +   R++GVSN+
Sbjct: 131 GTKLNAIDDSIAPTEAWIGLEQCYQEGLCRSIGVSNF 167


>UniRef50_Q8SSK6 Cluster: ALDOSE REDUCTASE; n=1; Encephalitozoon
           cuniculi|Rep: ALDOSE REDUCTASE - Encephalitozoon
           cuniculi
          Length = 301

 Score = 81.8 bits (193), Expect = 4e-14
 Identities = 44/109 (40%), Positives = 63/109 (57%)
 Frame = +3

Query: 252 LNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPK 431
           LNNG E+P +GL T+ M     +   + +AL  GYR  DTA +YGNE  +    KKL  +
Sbjct: 8   LNNGKEIPTVGLGTWGMEDEAVLEGAIRNALSLGYRHIDTAFIYGNEKMIGNILKKLFDE 67

Query: 432 YKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNP 578
             ++R D+FI SKL    +G     E     +L++L +DY+DLYL+H P
Sbjct: 68  GVVQRKDLFITSKLWNTFHG---CPEDGLRRSLNDLQMDYVDLYLIHWP 113


>UniRef50_Q6NII7 Cluster: Putative oxidoreductase; n=2;
           Corynebacterium|Rep: Putative oxidoreductase -
           Corynebacterium diphtheriae
          Length = 290

 Score = 81.4 bits (192), Expect = 6e-14
 Identities = 46/116 (39%), Positives = 68/116 (58%)
 Frame = +3

Query: 231 ILPQQFTLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFA 410
           I+P   TLN+G EMPAIG  T+K+       + V  A++ GYR  DTA+LY NE  +  A
Sbjct: 10  IIPT-ITLNDGTEMPAIGFGTYKLRE-QDAYRAVRSAIEVGYRHIDTASLYKNEEEVGRA 67

Query: 411 FKKLLPKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNP 578
               +   ++ R ++FI +K+   +  G  +T+R+F  +L  LGLDYID  +VH P
Sbjct: 68  VADAITAGEVARDELFITTKVWN-DMHGDQLTQRSFQESLHRLGLDYIDCCMVHWP 122


>UniRef50_Q1RFP0 Cluster: 2,5-diketo-D-gluconic acid reductase A;
           n=21; Bacteria|Rep: 2,5-diketo-D-gluconic acid reductase
           A - Escherichia coli (strain UTI89 / UPEC)
          Length = 294

 Score = 81.4 bits (192), Expect = 6e-14
 Identities = 47/150 (31%), Positives = 78/150 (52%)
 Frame = +3

Query: 252 LNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPK 431
           L+N ++MP +G   F++       Q+V +A++ GYR+ DTAA+YGNE  +  A ++ + +
Sbjct: 11  LSNNLKMPMMGFGVFQVTDKDVCKQSVLNAIRTGYRLIDTAAVYGNEDAVGEAVREAISE 70

Query: 432 YKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLDFENRN 611
               R ++FI SKL   +     +       +L   GL+Y DLYL+H             
Sbjct: 71  GLCTREELFITSKLWVQDMLNQDIAAAGIEASLKKSGLEYFDLYLLH------------Q 118

Query: 612 SSRIRKQTWATLVDLYHDHKIRALGVSNYF 701
           + R     W  L D Y + K++A+GVSN++
Sbjct: 119 AMRDYFSAWRALEDAYEEGKLKAIGVSNFY 148


>UniRef50_Q9ZBW7 Cluster: Putative oxidoreductase; n=2;
           Actinomycetales|Rep: Putative oxidoreductase -
           Streptomyces coelicolor
          Length = 277

 Score = 81.0 bits (191), Expect = 8e-14
 Identities = 56/149 (37%), Positives = 81/149 (54%)
 Frame = +3

Query: 252 LNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPK 431
           LNNGVEMP +G   +++         V  AL+AGYR  DTAA+YGNE     A    +  
Sbjct: 10  LNNGVEMPQLGFGVWQVPDD-DAQTAVALALEAGYRSIDTAAIYGNEEGTGRA----IAA 64

Query: 432 YKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLDFENRN 611
             L R D+F+ +KL   + G  + T RAF  +++ LGL+Y+DLYL+H P   K  + +  
Sbjct: 65  SGLAREDLFVTTKLWNSDQGYDS-TLRAFDTSMAKLGLEYLDLYLIHWPMPAKERYVD-- 121

Query: 612 SSRIRKQTWATLVDLYHDHKIRALGVSNY 698
                  T+     L  D ++RA+GVSN+
Sbjct: 122 -------TYKAFEKLLADGRVRAIGVSNF 143


>UniRef50_Q927E1 Cluster: Lin2848 protein; n=13; Listeria|Rep:
           Lin2848 protein - Listeria innocua
          Length = 280

 Score = 81.0 bits (191), Expect = 8e-14
 Identities = 54/151 (35%), Positives = 76/151 (50%)
 Frame = +3

Query: 246 FTLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLL 425
           + LNNG+EMP  G   +K+     +   ++ A+  GYR+FDTA+ Y NE  L   F    
Sbjct: 9   YRLNNGIEMPRHGFGVYKLTDEQRMRTALETAVDVGYRLFDTASFYHNEKELGDFF---- 64

Query: 426 PKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLDFEN 605
               LKR + F+ +K+     G    T RAF  +   L LD +DLYLVH P   K D   
Sbjct: 65  ASSGLKRDEFFVTTKMWNTEQGYDE-TLRAFEKSQKKLQLDQVDLYLVHWP---KQD--- 117

Query: 606 RNSSRIRKQTWATLVDLYHDHKIRALGVSNY 698
                   +TW  +  LY +  +RA+GVSN+
Sbjct: 118 -----TFFETWRAVEKLYDEGLVRAIGVSNF 143


>UniRef50_A5KSS3 Cluster: Aldehyde reductase; n=1; candidate
           division TM7 genomosp. GTL1|Rep: Aldehyde reductase -
           candidate division TM7 genomosp. GTL1
          Length = 299

 Score = 81.0 bits (191), Expect = 8e-14
 Identities = 51/159 (32%), Positives = 85/159 (53%), Gaps = 9/159 (5%)
 Frame = +3

Query: 249 TLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLP 428
           TL N   +P +G  T+++    T    V+ A+KAGYR  D A +YGNE  +    ++ + 
Sbjct: 5   TLRNKQTLPLLGYGTWELPTG-TTADLVETAIKAGYRHIDCAMIYGNEKEVGEGIRRTID 63

Query: 429 KYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLV-------HNPGIY 587
           +  +KR D+F+ SKL   ++    V   A   TL++LGLDY+DLYL+       H   + 
Sbjct: 64  QGVVKREDLFVTSKLWNTDHAQVDVGV-ACRKTLNDLGLDYLDLYLIHWGVAFEHGDNLE 122

Query: 588 KLDFEN--RNSSRIRKQTWATLVDLYHDHKIRALGVSNY 698
            LD +   + S    K+TW  + +L     ++++GV+N+
Sbjct: 123 PLDDDGVAKFSFISMKETWQAMEELVEQGLVKSMGVANF 161


>UniRef50_Q7ZA52 Cluster: Aldose reductase; n=6; Pezizomycotina|Rep:
           Aldose reductase - Magnaporthe grisea (Rice blast
           fungus) (Pyricularia grisea)
          Length = 312

 Score = 81.0 bits (191), Expect = 8e-14
 Identities = 58/165 (35%), Positives = 85/165 (51%), Gaps = 12/165 (7%)
 Frame = +3

Query: 240 QQFTLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKK 419
           + FTLN G ++PA GL T++ G    + + V  A+K+GYR+ D A +YGNE  +    ++
Sbjct: 4   KDFTLNTGAKIPAFGLGTWQ-GDKGVIKEAVLTAIKSGYRLIDGAYVYGNEEEVGQGIRE 62

Query: 420 LLPKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVH-----NPGI 584
            +    +KR D+F++SK   C        E     +L  LGLDY+DLYLVH     NP  
Sbjct: 63  AISSGIVKREDLFVVSK---CWATYTTRCELGLDQSLKLLGLDYVDLYLVHWPILMNPEG 119

Query: 585 YKLDF-ENRNSSR------IRKQTWATLVDLYHDHKIRALGVSNY 698
               F ++ + SR          TW  +  L    K +A+GVSNY
Sbjct: 120 NDEKFPKHADGSRDIIHTHNHVDTWKLMEKLPATGKTKAVGVSNY 164


>UniRef50_A6RKL9 Cluster: Putative uncharacterized protein; n=3;
           Sclerotiniaceae|Rep: Putative uncharacterized protein -
           Botryotinia fuckeliana B05.10
          Length = 360

 Score = 81.0 bits (191), Expect = 8e-14
 Identities = 48/147 (32%), Positives = 81/147 (55%), Gaps = 2/147 (1%)
 Frame = +3

Query: 264 VEMPAIGLDTFKMGHF-YTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPKYKL 440
           +  P IG  T+ +        + V  A++ GYR  D AA+YGNEV +    ++ L +  L
Sbjct: 37  ISQPLIGFGTWNLKVSPENTTEAVAYAIEIGYRQIDCAAVYGNEVAVGRGIEEGLKRAGL 96

Query: 441 KRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLDFENRNSSR 620
           KR DI++ SKL   ++G     E+  + TL +LGL+Y+DLYL+H P    + F +  +  
Sbjct: 97  KREDIWVTSKLWNDHHGSYENVEKGLNQTLQDLGLEYLDLYLIHWP----IGFSSNGAKN 152

Query: 621 I-RKQTWATLVDLYHDHKIRALGVSNY 698
           +   QT+ +++ L    ++  +GVSN+
Sbjct: 153 LDHVQTYKSMISL-PKSRVLNIGVSNF 178


>UniRef50_A7CWF9 Cluster: Aldehyde reductase; n=2; Bacteria|Rep:
           Aldehyde reductase - Opitutaceae bacterium TAV2
          Length = 347

 Score = 80.6 bits (190), Expect = 1e-13
 Identities = 49/118 (41%), Positives = 69/118 (58%), Gaps = 3/118 (2%)
 Frame = +3

Query: 234 LPQQFTLNNGVEMPAIGLDTFKMGHFYT--VLQTVDDALKAGYRMFDTAALYGNEVYLNF 407
           +PQ+ TL +G  MPAIG+ TF   H     V  +V  A + GYR FD AA+Y NE  +  
Sbjct: 16  IPQR-TLASGARMPAIGMGTFGSDHAAPGEVAASVYAAAELGYRHFDCAAVYSNEREIGA 74

Query: 408 AFKKLLPKYK-LKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNP 578
            F+++L     ++R D++I SKL    +    V   AF  +L +LGLDY+DLYL+H P
Sbjct: 75  TFRRILTSNTGIRREDLWITSKLWNDKHAEADVIP-AFEKSLRDLGLDYLDLYLIHWP 131


>UniRef50_A4FEB9 Cluster: 2,5-diketo-D-gluconic acid reductase; n=1;
           Saccharopolyspora erythraea NRRL 2338|Rep:
           2,5-diketo-D-gluconic acid reductase - Saccharopolyspora
           erythraea (strain NRRL 23338)
          Length = 159

 Score = 80.6 bits (190), Expect = 1e-13
 Identities = 49/110 (44%), Positives = 63/110 (57%)
 Frame = +3

Query: 249 TLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLP 428
           TLNNGVEMP +G   F++    T    V  AL+AGYR  DTAA YGNE     A  + L 
Sbjct: 8   TLNNGVEMPQLGYGVFQVPEDETAA-AVGAALEAGYRSIDTAAAYGNEA----AVGRALA 62

Query: 429 KYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNP 578
              L R ++F+ +KL   + G      RAF  +L  LGLD++DLYL+H P
Sbjct: 63  GSGLARDELFVTTKLWNADQGYDNAL-RAFDTSLELLGLDHLDLYLIHWP 111


>UniRef50_A1D4E3 Cluster: D-xylose reductase (Xyl1), putative; n=5;
           Pezizomycotina|Rep: D-xylose reductase (Xyl1), putative
           - Neosartorya fischeri (strain ATCC 1020 / DSM 3700 /
           NRRL 181)(Aspergillus fischerianus (strain ATCC 1020 /
           DSM 3700 / NRRL 181))
          Length = 321

 Score = 80.6 bits (190), Expect = 1e-13
 Identities = 56/163 (34%), Positives = 84/163 (51%), Gaps = 14/163 (8%)
 Frame = +3

Query: 252 LNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPK 431
           LN+G +MP +G   +K+ +  T    +  A+KAGYR+FD A  YGNEV       + + +
Sbjct: 8   LNSGYDMPLVGFGLWKVNN-ETCADQIYHAIKAGYRLFDGACDYGNEVEAGKGVARAIQE 66

Query: 432 YKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYK-LD---- 596
             +KR D+FI+SKL    + G  V E      L++ GLDY DL++VH P   K +D    
Sbjct: 67  GIVKREDLFIVSKLWNSFHDGDRV-EPICRKQLADWGLDYFDLFIVHFPIALKYVDPAVR 125

Query: 597 ------FENRN---SSRIRKQTWATLVDLYHDHKIRALGVSNY 698
                  EN     S+   ++TW  +  L      R++GVSN+
Sbjct: 126 YPPGWLSENNKLEFSNASIQETWTAMESLVDKKLARSIGVSNF 168


>UniRef50_Q235V6 Cluster: Oxidoreductase, aldo/keto reductase family
           protein; n=2; Tetrahymena thermophila SB210|Rep:
           Oxidoreductase, aldo/keto reductase family protein -
           Tetrahymena thermophila SB210
          Length = 332

 Score = 80.2 bits (189), Expect = 1e-13
 Identities = 50/149 (33%), Positives = 76/149 (51%)
 Frame = +3

Query: 252 LNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPK 431
           LNNG  MP +GL T+ +     +   +  AL AGYR  DTA  Y NE  +  + K +  +
Sbjct: 10  LNNGQIMPLVGLGTYLLNSKEEMTNLLRTALDAGYRHIDTAVNYQNEAMIGESLKTIFKE 69

Query: 432 YKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLDFENRN 611
            K  R D+FI+SK+ P N G   +   +   +L  L LDY+DLY +H P  +  + E   
Sbjct: 70  GKYSRKDLFIVSKVFP-NKGINML--ESVKKSLKELQLDYVDLYYLHFPLGFLSEKEEFV 126

Query: 612 SSRIRKQTWATLVDLYHDHKIRALGVSNY 698
              +    WA L + +     +++GVSN+
Sbjct: 127 HLPVH-VAWAQLEEAHRLGLAKSIGVSNF 154


>UniRef50_Q4P4P1 Cluster: Putative uncharacterized protein; n=1;
           Ustilago maydis|Rep: Putative uncharacterized protein -
           Ustilago maydis (Smut fungus)
          Length = 322

 Score = 80.2 bits (189), Expect = 1e-13
 Identities = 50/156 (32%), Positives = 77/156 (49%)
 Frame = +3

Query: 231 ILPQQFTLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFA 410
           I  Q+  LNNG E+P + L  +K  +  +       A  AGYR  D+AA Y NE  +  A
Sbjct: 14  ISTQRIKLNNGQEIPQVALGVYKAPNDGSTENACKWAFDAGYRHIDSAARYMNEESVGRA 73

Query: 411 FKKLLPKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYK 590
             +   +  + R +IFI SKL   ++   A    A  ++L  L +DY+D+YL+H+PG   
Sbjct: 74  LAEWTKENNVPRSEIFITSKLWDADHDKAAA---AIEDSLKKLNVDYMDMYLMHSPGTM- 129

Query: 591 LDFENRNSSRIRKQTWATLVDLYHDHKIRALGVSNY 698
                   +  R + W  L +     KI+ +GVSN+
Sbjct: 130 -------GAEKRLEAWKALEEAVDAGKIKTIGVSNF 158


>UniRef50_Q890A0 Cluster: Oxidoreductase; n=6; Lactobacillales|Rep:
           Oxidoreductase - Lactobacillus plantarum
          Length = 282

 Score = 79.8 bits (188), Expect = 2e-13
 Identities = 51/158 (32%), Positives = 73/158 (46%)
 Frame = +3

Query: 231 ILPQQFTLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFA 410
           +L   + L NGV +P +   T+++       Q V  AL AGYR  DTA  Y NE  +  A
Sbjct: 3   VLTTMYQLANGVNIPKVAFGTWQIPGGEATYQAVRAALAAGYRHIDTALAYQNEASVGQA 62

Query: 411 FKKLLPKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYK 590
            +       + R  IF+ +K LP            F  +L NLGLDY+DLYLVH P  + 
Sbjct: 63  IR----DSGIPREQIFVTTK-LPAETKSYQGALNDFDRSLKNLGLDYVDLYLVHAP--WP 115

Query: 591 LDFENRNSSRIRKQTWATLVDLYHDHKIRALGVSNYFI 704
                R         W  +  +Y   + +A+GVSN+ +
Sbjct: 116 WGQVGRVYDEANLDVWQAMEAIYQSGRAKAIGVSNFAV 153


>UniRef50_Q7JVH6 Cluster: LD24696p; n=2; Sophophora|Rep: LD24696p -
           Drosophila melanogaster (Fruit fly)
          Length = 311

 Score = 79.8 bits (188), Expect = 2e-13
 Identities = 52/155 (33%), Positives = 80/155 (51%), Gaps = 6/155 (3%)
 Frame = +3

Query: 252 LNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPK 431
           LNNG EMP +GL T+K         +   AL  GYR  DTA +Y NE  +  A  + + +
Sbjct: 10  LNNGREMPTLGLGTWKSFES-DAYHSTRHALDVGYRHLDTAFVYENEAEVGQAISEKIAE 68

Query: 432 YKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLDFENRN 611
             + R ++F+ +KL   ++   A+ ERA   +LSNLGL+Y+DLYL+H P   K   ++  
Sbjct: 69  GVVTREEVFVTTKLGGIHHDP-ALVERACRLSLSNLGLEYVDLYLMHMPVGQKFHNDSNV 127

Query: 612 SSRIR------KQTWATLVDLYHDHKIRALGVSNY 698
              +         TW  +  L      R++G+SN+
Sbjct: 128 HGTLELTDVDYLDTWREMEKLVDLGLTRSIGLSNF 162


>UniRef50_Q4PE96 Cluster: Putative uncharacterized protein; n=1;
           Ustilago maydis|Rep: Putative uncharacterized protein -
           Ustilago maydis (Smut fungus)
          Length = 293

 Score = 79.8 bits (188), Expect = 2e-13
 Identities = 51/160 (31%), Positives = 77/160 (48%)
 Frame = +3

Query: 219 DFKYILPQQFTLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVY 398
           D K  L    T+ +G  MP  G+  + M         ++   KAGYR  DTA  Y NE  
Sbjct: 10  DEKLTLGSSITMVDGYAMPRFGIGAWDMRGSECKQALLNAFDKAGYRHVDTARYYRNEAD 69

Query: 399 LNFAFKKLLPKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNP 578
              A ++      + R ++F  +K+     GGG+ T  A  ++L+  GLDY+DL L+H P
Sbjct: 70  CGEAVREC----SVPRSELFYTTKVYLNEMGGGSKTRLAVEDSLAKAGLDYLDLVLLHAP 125

Query: 579 GIYKLDFENRNSSRIRKQTWATLVDLYHDHKIRALGVSNY 698
                        + R  +W TL +L  + K+R+LGVSN+
Sbjct: 126 D---------GGKKFRLDSWDTLTELVQEGKVRSLGVSNF 156


>UniRef50_Q8EVT8 Cluster: Oxidoreductase-aldo/keto reductase family;
           n=1; Mycoplasma penetrans|Rep: Oxidoreductase-aldo/keto
           reductase family - Mycoplasma penetrans
          Length = 299

 Score = 79.4 bits (187), Expect = 2e-13
 Identities = 45/115 (39%), Positives = 66/115 (57%)
 Frame = +3

Query: 237 PQQFTLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFK 416
           P   TLN+G ++P IGL T  + H  T    +  AL+ G R+FDTA+LYGNE  +     
Sbjct: 34  PPLLTLNDGYQIPIIGLGTTSL-HNQTCKNAIKAALEIGIRLFDTASLYGNEKEVG---- 88

Query: 417 KLLPKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPG 581
           + + +  + R +IF+I+KL P      A  E+A    L+ L  DYID+ L+H+PG
Sbjct: 89  ETIRESNINRNEIFVITKLYP--GAQFANPEKAIEEALNKLNTDYIDMMLLHHPG 141


>UniRef50_UPI00015B56A2 Cluster: PREDICTED: similar to GA10458-PA;
           n=2; Nasonia vitripennis|Rep: PREDICTED: similar to
           GA10458-PA - Nasonia vitripennis
          Length = 569

 Score = 79.0 bits (186), Expect = 3e-13
 Identities = 47/114 (41%), Positives = 63/114 (55%)
 Frame = +3

Query: 249 TLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLP 428
           T N+G +MP IGL TF +     V + V  A++ GYR  DTA  Y NE  +  A ++ + 
Sbjct: 7   TFNDGYKMPMIGLGTF-LSKPGEVAEAVKYAIEVGYRHVDTAFFYENEKEIGSAIREKIN 65

Query: 429 KYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYK 590
              +KR DIF+ +KL  CN         A   +L NLG DYIDL+LVH P  +K
Sbjct: 66  DGTIKREDIFVTTKLW-CNSHKEDEVVPACKKSLENLGFDYIDLFLVHWPFAFK 118



 Score = 65.3 bits (152), Expect = 4e-09
 Identities = 43/122 (35%), Positives = 65/122 (53%), Gaps = 7/122 (5%)
 Frame = +3

Query: 354 YRMFDTAALYGNEVYLNFAFKKLLPKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLS 533
           YR  DTA LY NE Y+  A ++ +    +KR D+F+ +KL    +    V   A   +L+
Sbjct: 301 YRHIDTAYLYDNEKYIGNAIREKIKDGTVKREDLFVTTKLSYYAHKESEVVP-ACKQSLN 359

Query: 534 NLGLDYIDLYLVHNPGIYKLDFENRNSS-------RIRKQTWATLVDLYHDHKIRALGVS 692
           +LGLDYIDLYL+H P I +    N+N+S           +TW  + +       R++GVS
Sbjct: 360 DLGLDYIDLYLIHWP-IRRYFRHNKNASGKLLLSDTDYLETWKGMEECKRQGLARSIGVS 418

Query: 693 NY 698
           N+
Sbjct: 419 NF 420


>UniRef50_UPI00006CCCD7 Cluster: oxidoreductase, aldo/keto reductase
           family protein; n=1; Tetrahymena thermophila SB210|Rep:
           oxidoreductase, aldo/keto reductase family protein -
           Tetrahymena thermophila SB210
          Length = 323

 Score = 79.0 bits (186), Expect = 3e-13
 Identities = 57/169 (33%), Positives = 84/169 (49%), Gaps = 8/169 (4%)
 Frame = +3

Query: 216 EDFKYILPQQFTLNNGVEMPAIGLDT--FKMGHFYTVLQT---VDDALKAGYRMFDTAAL 380
           +D KY+      LNNG +MP +GL T  + +    TV +    + +AL  GYR FDTA  
Sbjct: 10  QDIKYV-----QLNNGYKMPLLGLGTQPYDIVTRVTVEEMTTLLSNALDFGYRNFDTAKQ 64

Query: 381 YGNEVYLNFAFKKLLPKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDL 560
           Y NEV +  AF+ +  + K KR D+FI +KL P  +      +    N+L  L   YIDL
Sbjct: 65  YRNEVEIGQAFQNIFQQGKYKREDVFITTKLFP--FKIEKKIKEVVQNSLDQLQTSYIDL 122

Query: 561 YLVH---NPGIYKLDFENRNSSRIRKQTWATLVDLYHDHKIRALGVSNY 698
           YL+     P +   D     + R   + W  L +      IR++GV+N+
Sbjct: 123 YLIQWSFTPVLTNFDGSVAVNHRPIHEVWRELEECVELGMIRSIGVANF 171


>UniRef50_UPI0000498F1F Cluster: oxidoreductase, aldo/keto reductase
           family; n=2; Entamoeba histolytica HM-1:IMSS|Rep:
           oxidoreductase, aldo/keto reductase family - Entamoeba
           histolytica HM-1:IMSS
          Length = 305

 Score = 79.0 bits (186), Expect = 3e-13
 Identities = 52/154 (33%), Positives = 81/154 (52%), Gaps = 1/154 (0%)
 Frame = +3

Query: 246 FTLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLL 425
           FTLNNG ++P +GL T+ M     V + V+ A+K GYR  D A  YGNE  +    K  +
Sbjct: 5   FTLNNGYKIPKLGLGTW-MSANGEVGKAVEIAIKNGYRHIDCAKAYGNEKEVGDGIKSAI 63

Query: 426 PKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNP-GIYKLDFE 602
            K  +KR ++F+ +KL   +     V   A   +L  L L+Y+DLY++H P    K   E
Sbjct: 64  AKGYVKREELFVTTKLWSTDKHKEDV-RPACLESLKKLQLEYLDLYIIHIPLTADKKTGE 122

Query: 603 NRNSSRIRKQTWATLVDLYHDHKIRALGVSNYFI 704
                   ++TW  +  L  +  ++++GVSN+ I
Sbjct: 123 FTEEIIPIEETWREMEKLVEEGLVKSIGVSNFNI 156


>UniRef50_Q2S340 Cluster: Aldehyde reductase; n=10; Bacteria|Rep:
           Aldehyde reductase - Salinibacter ruber (strain DSM
           13855)
          Length = 321

 Score = 79.0 bits (186), Expect = 3e-13
 Identities = 56/163 (34%), Positives = 80/163 (49%), Gaps = 8/163 (4%)
 Frame = +3

Query: 240 QQFTLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKK 419
           Q  +  NG EMP IGL T+K      V + V  AL+AGYR  D A +Y NE  +  A   
Sbjct: 2   QSISFENGDEMPMIGLGTWKSPPG-EVYEAVTTALEAGYRHVDCAPIYKNETEVGAALSD 60

Query: 420 LLPKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIY--KL 593
                 ++R D+++ SKL    +    V   A   TLS+L LD +DLYL+H P     ++
Sbjct: 61  SFDAGGIRRDDVWVTSKLWNNAHHPDDV-RPALEQTLSDLRLDALDLYLIHWPVALQPEV 119

Query: 594 DFENRNSSRIR------KQTWATLVDLYHDHKIRALGVSNYFI 704
           DF       +        +TWA +  L  D  +R +GVSN+ +
Sbjct: 120 DFPESPDDFVSPEAVPLTETWAAMEALKKDGLVRHIGVSNFSV 162


>UniRef50_Q1VRG6 Cluster: YvgN; n=1; Psychroflexus torquis ATCC
           700755|Rep: YvgN - Psychroflexus torquis ATCC 700755
          Length = 280

 Score = 79.0 bits (186), Expect = 3e-13
 Identities = 53/152 (34%), Positives = 78/152 (51%), Gaps = 2/152 (1%)
 Frame = +3

Query: 252 LNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPK 431
           LN+G  +P +G  T+K      +      AL  GYR+ DT A+Y NE     A  K +  
Sbjct: 5   LNDGNRIPIVGFGTYKANEEEGIKSIQKSALTLGYRLIDTVAIYQNEE----AVGKAIKA 60

Query: 432 YKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNP--GIYKLDFEN 605
             + R +IF+ +KL   N  G   T  A   +L  L L+YIDLYL+H P   I   D++ 
Sbjct: 61  RGVLREEIFVTTKLWRENL-GYKQTRIALDESLRKLDLNYIDLYLIHWPANAINYKDWQK 119

Query: 606 RNSSRIRKQTWATLVDLYHDHKIRALGVSNYF 701
            N+      TW  + +L  + KI++LGVSN++
Sbjct: 120 TNA-----DTWRAMEELQAEGKIKSLGVSNFW 146


>UniRef50_A0JX62 Cluster: 2,5-didehydrogluconate reductase; n=9;
           Bacteria|Rep: 2,5-didehydrogluconate reductase -
           Arthrobacter sp. (strain FB24)
          Length = 291

 Score = 79.0 bits (186), Expect = 3e-13
 Identities = 57/165 (34%), Positives = 87/165 (52%), Gaps = 13/165 (7%)
 Frame = +3

Query: 243 QFTLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKL 422
           + +LNNGV +  +G   +K+         V  AL+AGYR FDTAA+YGNE  +  A   L
Sbjct: 6   RLSLNNGVLIDQLGFGLYKVPPA-DAAGLVTMALEAGYRHFDTAAMYGNETGVGKAIGAL 64

Query: 423 L-------------PKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLY 563
                             L R D+F+ +K+   ++G  A T RAF  ++SNLG++Y+DLY
Sbjct: 65  AGFAGGGPAGGSGEAAPSLSREDLFVTTKVWNDDHGYDA-TMRAFDTSMSNLGMEYVDLY 123

Query: 564 LVHNPGIYKLDFENRNSSRIRKQTWATLVDLYHDHKIRALGVSNY 698
           L+H P   +  F          +++  +  LY + +IRA+GVSN+
Sbjct: 124 LIHWPCARRGLF---------TESYRAMETLYREGRIRAIGVSNF 159


>UniRef50_A2R6Z3 Cluster: Catalytic activity: an alcohol + NADP(+)
           <=> an aldehyde + NADPH; n=9; Pezizomycotina|Rep:
           Catalytic activity: an alcohol + NADP(+) <=> an aldehyde
           + NADPH - Aspergillus niger
          Length = 345

 Score = 79.0 bits (186), Expect = 3e-13
 Identities = 58/166 (34%), Positives = 85/166 (51%), Gaps = 11/166 (6%)
 Frame = +3

Query: 234 LPQQFTLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAF 413
           L + F LN G +MPA+GL T++      V   V  ALK GYR  D AA+YGNE  +    
Sbjct: 3   LNRTFKLNTGYDMPAVGLGTWQSKKD-EVRDAVIAALKCGYRHIDAAAVYGNEQEVGDGM 61

Query: 414 KKLLPKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYK- 590
           +       + R +IF+ SKL   ++    V E A   +L++L  DY+DLYL+H P  ++ 
Sbjct: 62  R----LSGVPREEIFLTSKLWNTHHHPENV-EEAVDKSLADLQTDYLDLYLIHWPVAFRY 116

Query: 591 ----LDFENRNSSRIR------KQTWATLVDLYHDHKIRALGVSNY 698
               +   N  +  I       K TWA +  L    K+R++GVSN+
Sbjct: 117 STTTIQPVNEQTGLIDVVDVPIKDTWAAMEKLVEKGKVRSIGVSNF 162


>UniRef50_P47137 Cluster: Probable oxidoreductase YJR096W; n=8;
           Saccharomycetales|Rep: Probable oxidoreductase YJR096W -
           Saccharomyces cerevisiae (Baker's yeast)
          Length = 282

 Score = 79.0 bits (186), Expect = 3e-13
 Identities = 52/159 (32%), Positives = 85/159 (53%), Gaps = 3/159 (1%)
 Frame = +3

Query: 231 ILPQQFTLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFA 410
           ++P+ + L+NG ++P+I L T+ +    T  + V + +K GYR FDTA LYGNE  +   
Sbjct: 1   MVPKFYKLSNGFKIPSIALGTYDIPRSQTA-EIVYEGVKCGYRHFDTAVLYGNEKEVGDG 59

Query: 411 FKKLLPK--YKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNL-GLDYIDLYLVHNPG 581
             K L +     KR +IF  +KL   +  G    + A    L+ + GL YIDL L+H+P 
Sbjct: 60  IIKWLNEDPGNHKREEIFYTTKLWN-SQNGYKRAKAAIRQCLNEVSGLQYIDLLLIHSP- 117

Query: 582 IYKLDFENRNSSRIRKQTWATLVDLYHDHKIRALGVSNY 698
                      S++R +TW  + +   +  ++++GVSNY
Sbjct: 118 --------LEGSKLRLETWRAMQEAVDEGLVKSIGVSNY 148


>UniRef50_UPI00006CD296 Cluster: oxidoreductase, aldo/keto reductase
           family protein; n=1; Tetrahymena thermophila SB210|Rep:
           oxidoreductase, aldo/keto reductase family protein -
           Tetrahymena thermophila SB210
          Length = 295

 Score = 78.6 bits (185), Expect = 4e-13
 Identities = 50/150 (33%), Positives = 75/150 (50%), Gaps = 1/150 (0%)
 Frame = +3

Query: 252 LNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPK 431
           L NG ++P  GL T+K+     ++  +  AL  GYR  DTA +Y NE  +  A +++  +
Sbjct: 10  LCNGSKLPVFGLGTYKVVSKEEMVTFLRTALDLGYRHIDTAIMYENEKQIGDALQEIYKE 69

Query: 432 YKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLD-FENR 608
            K KR D+F+++KL           E     +L NL  +YIDLYL+H       D FE  
Sbjct: 70  GKYKREDLFLVTKLFS---NKNTKVEDQVRQSLQNLQTNYIDLYLLHYASSPPTDQFELT 126

Query: 609 NSSRIRKQTWATLVDLYHDHKIRALGVSNY 698
           +      Q WA   +L     IR +G+SN+
Sbjct: 127 HKPVF--QVWAEFEELVQKGLIRNIGISNF 154


>UniRef50_A4RQH8 Cluster: Predicted protein; n=2; Ostreococcus|Rep:
           Predicted protein - Ostreococcus lucimarinus CCE9901
          Length = 337

 Score = 78.6 bits (185), Expect = 4e-13
 Identities = 52/148 (35%), Positives = 75/148 (50%), Gaps = 1/148 (0%)
 Frame = +3

Query: 258 NGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPKYK 437
           NG+ +P +GL T+K      V   V DAL AGY   D AA Y NE  +  A ++   +  
Sbjct: 12  NGLRIPRVGLGTWK-ARPNEVRDAVRDALGAGYAHVDCAAAYANESEVGEALREAFERGD 70

Query: 438 LKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLDFENRNSS 617
            KR D+F+ SKL         V E A   TL++LG+ Y+DLYL+H P  +K     +  +
Sbjct: 71  AKREDVFVTSKLWNDRRRPRDVRE-ALMTTLNDLGVGYLDLYLIHWPVAWKRGTVLQPDA 129

Query: 618 RIR-KQTWATLVDLYHDHKIRALGVSNY 698
                + W+ L     D  +R +GVSN+
Sbjct: 130 EASIAECWSELERCVADGLVRHIGVSNF 157


>UniRef50_Q968S3 Cluster: Aldoketoreductase-like protein; n=1;
           Orconectes limosus|Rep: Aldoketoreductase-like protein -
           Orconectes limosus (Spinycheek crayfish)
          Length = 336

 Score = 78.6 bits (185), Expect = 4e-13
 Identities = 47/130 (36%), Positives = 69/130 (53%), Gaps = 6/130 (4%)
 Frame = +3

Query: 252 LNNGVEMPAIGLDTFKMGHF-----YTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFK 416
           LN+G  +P +GL T  +G         V   ++ AL+ GYR FD+AA YGNE  +    +
Sbjct: 16  LNSGSHIPVMGLGTGSLGRNGKMSEEAVTAVLETALECGYRHFDSAAYYGNEAIIGQVLR 75

Query: 417 KLLPKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNP-GIYKL 593
           + + + K+KR ++FI +K LP          R    +L NL L Y+DLYLVH P GI   
Sbjct: 76  RWISEGKVKREELFITTK-LPTRGNREKDVARFLQKSLDNLRLPYVDLYLVHYPCGILDT 134

Query: 594 DFENRNSSRI 623
           D E  ++  +
Sbjct: 135 DRERLSADEV 144


>UniRef50_Q9C1X5 Cluster: Xylose and arabinose reductase; n=1;
           Schizosaccharomyces pombe|Rep: Xylose and arabinose
           reductase - Schizosaccharomyces pombe (Fission yeast)
          Length = 283

 Score = 78.6 bits (185), Expect = 4e-13
 Identities = 53/150 (35%), Positives = 74/150 (49%)
 Frame = +3

Query: 249 TLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLP 428
           TL NG+ +P IG   F +  +      V  AL +GYR  DTAA+YGNE     A      
Sbjct: 12  TLTNGMVIPRIGFGAFML-KYNECYGLVTQALDSGYRHIDTAAVYGNEDICGKAIVDWCE 70

Query: 429 KYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLDFENR 608
           K  +KR DIF+ SKL  C+      T  A  ++L +LG  YIDL+L+ +P          
Sbjct: 71  KNNVKRTDIFLTSKLANCS--DYYSTRAAIRSSLHHLG-TYIDLFLIQSPA--------- 118

Query: 609 NSSRIRKQTWATLVDLYHDHKIRALGVSNY 698
              + R  +W  + +      IR++GVSNY
Sbjct: 119 GGKKSRIASWKAMEEFVDSGDIRSVGVSNY 148


>UniRef50_Q7VHE1 Cluster: Putative uncharacterized protein; n=1;
           Helicobacter hepaticus|Rep: Putative uncharacterized
           protein - Helicobacter hepaticus
          Length = 270

 Score = 78.2 bits (184), Expect = 5e-13
 Identities = 43/113 (38%), Positives = 66/113 (58%)
 Frame = +3

Query: 240 QQFTLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKK 419
           Q  TLNNGV+MP +GL T+ +       + + +A++ GYR+FD+A +Y NE  L  A   
Sbjct: 2   QTLTLNNGVKMPILGLGTYSLTG-KAGQKAMSEAIEVGYRLFDSAQMYNNEAELGAAINA 60

Query: 420 LLPKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNP 578
            + K  +KR + FI +KLL  +     + +++   +L  LGLDYID  L+H P
Sbjct: 61  AV-KGGIKREEFFIQTKLLESS--SEDLAKKSIEKSLKTLGLDYIDSLLIHMP 110


>UniRef50_Q4Q5N9 Cluster: Prostaglandin f synthase, putative; n=7;
           cellular organisms|Rep: Prostaglandin f synthase,
           putative - Leishmania major
          Length = 279

 Score = 77.8 bits (183), Expect = 7e-13
 Identities = 53/150 (35%), Positives = 80/150 (53%)
 Frame = +3

Query: 249 TLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLP 428
           TL+NGV++P +G+ T++      V+  +  A+ AGYR  DTA  Y NE  +     +   
Sbjct: 9   TLSNGVQVPQLGIGTWEAKDGNEVVN-IKWAVNAGYRHVDTAHYYKNEKGVGQGISEC-- 65

Query: 429 KYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLDFENR 608
              + R DIF+ +KL   ++G  +    AF  +   LG++Y+DLYL+H PG         
Sbjct: 66  --GVPRSDIFVTTKLWNYDHGYESALA-AFEQSRQALGVEYVDLYLIHWPG--------P 114

Query: 609 NSSRIRKQTWATLVDLYHDHKIRALGVSNY 698
           N S I  +TW     LY   K+RA+GVSN+
Sbjct: 115 NRSYI--ETWRAFEKLYEMKKVRAIGVSNF 142


>UniRef50_Q17G72 Cluster: Aldo-keto reductase; n=9;
           Endopterygota|Rep: Aldo-keto reductase - Aedes aegypti
           (Yellowfever mosquito)
          Length = 316

 Score = 77.8 bits (183), Expect = 7e-13
 Identities = 53/160 (33%), Positives = 88/160 (55%), Gaps = 10/160 (6%)
 Frame = +3

Query: 249 TLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLP 428
           T  NG  MPA+G  T++      V + +++AL+AGYR  DTA +Y NE  +    K+ + 
Sbjct: 8   TFENGTTMPALGFGTWRASD-EEVEKALNEALEAGYRHIDTAPVYLNEKTIGKVLKEWMD 66

Query: 429 KYKLKRGDIFIISKLLPCNYGGGAVT-ERAFHNTLSNLGLDYIDLYLVHNP-GIYKLD-- 596
             K+ R ++FI++KL P  +G  A T E+   N+L +L L+Y+DLY VH P  + ++D  
Sbjct: 67  AGKVTRDELFIVTKLPP--HGTRASTVEKFLKNSLDDLQLEYVDLYHVHVPFTVPEVDGP 124

Query: 597 FENRNSSRIRKQT------WATLVDLYHDHKIRALGVSNY 698
           F   +   + + T      W  + ++Y     R +G+SN+
Sbjct: 125 FLVEDGLIVLETTTDHVALWKAMEEVYEAGLARNIGLSNF 164


>UniRef50_UPI0000519CC2 Cluster: PREDICTED: similar to CG2767-PA;
           n=1; Apis mellifera|Rep: PREDICTED: similar to CG2767-PA
           - Apis mellifera
          Length = 321

 Score = 77.4 bits (182), Expect = 9e-13
 Identities = 56/162 (34%), Positives = 79/162 (48%), Gaps = 11/162 (6%)
 Frame = +3

Query: 252 LNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPK 431
           L NG  MP IG  T++      +   ++ AL+AGYR  DTA  Y NE  +    K     
Sbjct: 8   LPNGELMPIIGFGTWQAQE-KELEDALNIALEAGYRHIDTATSYENEKVIGDVLKNWFDS 66

Query: 432 YKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNP-GIYKL----- 593
            KLKR DIFI++K LP         E+    +L NL L+Y+DLYL+H P G  K+     
Sbjct: 67  KKLKRSDIFIVTK-LPAVGNRAEDVEKWIKTSLQNLRLEYLDLYLIHVPIGFEKVGDILH 125

Query: 594 DFENRNSSRIRKQT-----WATLVDLYHDHKIRALGVSNYFI 704
            F+     R+   T     WA +       + +A+G+SN+ I
Sbjct: 126 PFDENGHIRLDNSTNHVEIWAEMEKQVKCGRTKAIGLSNFNI 167


>UniRef50_Q8Y463 Cluster: Lmo2592 protein; n=40; Bacteria|Rep:
           Lmo2592 protein - Listeria monocytogenes
          Length = 283

 Score = 77.4 bits (182), Expect = 9e-13
 Identities = 53/149 (35%), Positives = 76/149 (51%)
 Frame = +3

Query: 252 LNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPK 431
           LNNGVE+P +G  T+++         V DA+KAGYR  DTA  Y NE     A  + +  
Sbjct: 6   LNNGVEVPILGFGTYQITDAAEAEHAVKDAIKAGYRHIDTAQSYMNEE----AVGRGIAA 61

Query: 432 YKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLDFENRN 611
             + R ++FI +K+   N     V   +F  +L  LGLDY+DL L+H P      F +  
Sbjct: 62  SGVDRKELFITTKIWVENVSYKGVMS-SFDRSLKRLGLDYVDLLLIHQP------FNDVY 114

Query: 612 SSRIRKQTWATLVDLYHDHKIRALGVSNY 698
            +      W  + +L    KIRA+GVSN+
Sbjct: 115 GA------WIAMEELQASGKIRAIGVSNF 137


>UniRef50_Q4PDR0 Cluster: Putative uncharacterized protein; n=1;
           Ustilago maydis|Rep: Putative uncharacterized protein -
           Ustilago maydis (Smut fungus)
          Length = 339

 Score = 77.0 bits (181), Expect = 1e-12
 Identities = 58/172 (33%), Positives = 90/172 (52%), Gaps = 19/172 (11%)
 Frame = +3

Query: 246 FTLNNGVEMPAIGLDTFK----MGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAF 413
           FTLN G ++P++G+  ++     G    ++  +  A+K GYR  DTA  Y NE  +  A 
Sbjct: 8   FTLNTGAKLPSVGMGCWQGQPGPGRDNELVDALVRAIKVGYRHLDTATGYRNEAEVGQAV 67

Query: 414 KKLLPKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNP-GIYK 590
           ++      + R +IF+ +KL P   GG     +   N+L+ LG+DYIDL+L+H P G  K
Sbjct: 68  RQS----GVARSEIFVTTKLRP---GGVHDVVQELENSLNELGIDYIDLWLLHWPQGFTK 120

Query: 591 LD--FENRNSSRIRKQ---------TWATLVDLY---HDHKIRALGVSNYFI 704
            D  F    S  +  Q         TWA + D++   H  K++A+GVSN+ I
Sbjct: 121 DDGGFGTGESFGLEHQKHLGPTFNETWAKMEDVFLNSHKGKVKAIGVSNFSI 172


>UniRef50_Q88TV9 Cluster: Oxidoreductase; n=4; Lactobacillus|Rep:
           Oxidoreductase - Lactobacillus plantarum
          Length = 288

 Score = 76.6 bits (180), Expect = 2e-12
 Identities = 47/110 (42%), Positives = 62/110 (56%)
 Frame = +3

Query: 249 TLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLP 428
           TLN+G  +PAIG  TF++    +  Q V +AL  GYR  DTA  Y NE  +  A K    
Sbjct: 8   TLNDGRAIPAIGFGTFQIPDDGSTYQAVKEALVIGYRHIDTAVAYFNEDEVGQAIK---- 63

Query: 429 KYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNP 578
              + R  I++ SKL   +YG  A + RA   +L+ L LDYIDLYL+H P
Sbjct: 64  DSGIPRDQIWVTSKLWLQDYGFDAAS-RAIDRSLTKLRLDYIDLYLIHQP 112


>UniRef50_A6VNW9 Cluster: Aldo/keto reductase precursor; n=1;
           Actinobacillus succinogenes 130Z|Rep: Aldo/keto
           reductase precursor - Actinobacillus succinogenes 130Z
          Length = 315

 Score = 76.2 bits (179), Expect = 2e-12
 Identities = 56/151 (37%), Positives = 80/151 (52%), Gaps = 2/151 (1%)
 Frame = +3

Query: 252 LNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPK 431
           LNNG+EMP IG+  + +    T  ++V +ALKAGYR+ DTA +Y NE     A  + +  
Sbjct: 47  LNNGIEMPIIGIGVWTLTPEQTE-KSVGEALKAGYRLIDTARMYRNEQ----AVGRAVRD 101

Query: 432 YKLKRGDIFIISKLLPCNYGGG--AVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLDFEN 605
             + R +IFI +K+    YG G  A  E A +  L  L  DYIDL L+H P        +
Sbjct: 102 SGIPREEIFITTKI----YGSGDYANAEAAINERLRLLDTDYIDLLLLHYP--------D 149

Query: 606 RNSSRIRKQTWATLVDLYHDHKIRALGVSNY 698
           +N ++     W  +       KIRA+G+SNY
Sbjct: 150 QNDTK----AWKVMEQFVKAGKIRAIGLSNY 176


>UniRef50_Q10494 Cluster: Probable oxidoreductase C26F1.07; n=2;
           Schizosaccharomyces pombe|Rep: Probable oxidoreductase
           C26F1.07 - Schizosaccharomyces pombe (Fission yeast)
          Length = 321

 Score = 76.2 bits (179), Expect = 2e-12
 Identities = 53/160 (33%), Positives = 83/160 (51%), Gaps = 9/160 (5%)
 Frame = +3

Query: 246 FTLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLL 425
           FTL +G ++P +GL T++     T    V  AL+ GYR  D AA+YGNE  +    K+  
Sbjct: 16  FTLADGSKIPGLGLGTWRSEPNQTK-NAVKTALQYGYRHIDAAAIYGNEDEVGDGIKES- 73

Query: 426 PKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLDFE- 602
               + R DI++ SKL  CN        +A   TL +L LDY+D YL+H P  +K   + 
Sbjct: 74  ---GVPRKDIWVTSKLW-CNAHAPEAVPKALEKTLKDLKLDYLDEYLIHWPVSFKTGEDK 129

Query: 603 ---NRNSSRIR-----KQTWATLVDLYHDHKIRALGVSNY 698
              +++ + I      ++TW  +  L    K+R +G+SN+
Sbjct: 130 FPKDKDGNLIYEKNPIEETWKAMEKLLETGKVRHIGLSNF 169


>UniRef50_A7ALH6 Cluster: Putative uncharacterized protein; n=1;
           Parabacteroides merdae ATCC 43184|Rep: Putative
           uncharacterized protein - Parabacteroides merdae ATCC
           43184
          Length = 301

 Score = 75.8 bits (178), Expect = 3e-12
 Identities = 51/149 (34%), Positives = 79/149 (53%)
 Frame = +3

Query: 252 LNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPK 431
           LNNG+EMP +G+ TF +       + V  A+K G+R+ DTA  YGNE  +       + +
Sbjct: 34  LNNGMEMPQLGVGTFLVKD--NAAERVCHAIKVGFRLIDTAQGYGNEKEVGEG----ICR 87

Query: 432 YKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLDFENRN 611
             + R ++FI +K+      GG V + +   +L++LG DYIDL L+H P    +      
Sbjct: 88  SGIDRRELFITTKVNTMEMRGGTVRQ-SLDKSLADLGTDYIDLVLIHWPVKGHI------ 140

Query: 612 SSRIRKQTWATLVDLYHDHKIRALGVSNY 698
                K+TW  L +     KIR++GVSN+
Sbjct: 141 -----KETWQILEEYVDKGKIRSIGVSNF 164


>UniRef50_A2QBD7 Cluster: Catalytic activity: an alcohol + NADP(+)
           <=> an aldehyde + NADPH; n=4; Trichocomaceae|Rep:
           Catalytic activity: an alcohol + NADP(+) <=> an aldehyde
           + NADPH - Aspergillus niger
          Length = 323

 Score = 75.8 bits (178), Expect = 3e-12
 Identities = 59/168 (35%), Positives = 85/168 (50%), Gaps = 11/168 (6%)
 Frame = +3

Query: 234 LPQQFTLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAF 413
           LP  FT+N G ++PA+G  T++      V   V+ AL+ GYR  D AA+Y NE  +    
Sbjct: 3   LPSHFTINTGAKIPAVGFGTWQAKPL-EVENAVEVALREGYRHIDCAAIYRNETEVGNGI 61

Query: 414 KKLLPKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYK- 590
           +K      + R +IFI  KL    +    V E A   TL +LG+ Y+DLYL+H P  +K 
Sbjct: 62  RKS----GVPREEIFITGKLWNTKHAPEDV-EPALDKTLQDLGVAYLDLYLMHWPCAFKG 116

Query: 591 ------LD----FENRNSSRIRKQTWATLVDLYHDHKIRALGVSNYFI 704
                 L+    F+  N   I   T+  +  L    K+RA+GVSN+ I
Sbjct: 117 GDKWFPLNDDGVFDLANIDYI--TTYRAMEKLLATGKVRAIGVSNFNI 162


>UniRef50_UPI00015B56A3 Cluster: PREDICTED: similar to aldo-keto
           reductase; n=1; Nasonia vitripennis|Rep: PREDICTED:
           similar to aldo-keto reductase - Nasonia vitripennis
          Length = 321

 Score = 75.4 bits (177), Expect = 4e-12
 Identities = 51/162 (31%), Positives = 88/162 (54%), Gaps = 10/162 (6%)
 Frame = +3

Query: 243 QFTLNNGVEMPAIGLDTFKMGHFYTVLQT-VDDALKAGYRMFDTAALYGNEVYLNFAFKK 419
           + TL++G ++P +GL T++ G+    ++  V  A+ AGYR FD A+ YGNE  +  A ++
Sbjct: 7   EITLSDGNKVPVLGLGTWQGGNDPDEVENAVKLAIDAGYRHFDCASFYGNEAEIGKAIQE 66

Query: 420 LLPKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLDF 599
            + +  +KR D+F+++K+         V   A   +L  LGL YIDLYLVH P  Y + +
Sbjct: 67  KIDQGVVKREDLFVVTKVWNDERKQELVV-AACKRSLKKLGLGYIDLYLVHWPFSYPILY 125

Query: 600 E-----NRNSSRIRK----QTWATLVDLYHDHKIRALGVSNY 698
           +       N+  + +    +TW  + +       R++GVSN+
Sbjct: 126 QYIVLPTYNAVTLDEVDYIETWRGMEECIKLGLTRSIGVSNF 167


>UniRef50_Q1IN88 Cluster: Aldehyde reductase; n=5; Bacteria|Rep:
           Aldehyde reductase - Acidobacteria bacterium (strain
           Ellin345)
          Length = 313

 Score = 75.4 bits (177), Expect = 4e-12
 Identities = 55/159 (34%), Positives = 83/159 (52%), Gaps = 11/159 (6%)
 Frame = +3

Query: 252 LNNGV-EMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLP 428
           L++G   +PA+G  T       T+  T  DAL AG+R FD A  Y NE  +  A +    
Sbjct: 13  LHHGAGHIPALGFGTLIADPALTITAT-RDALAAGFRHFDCAERYRNEREVGEALRAGRA 71

Query: 429 KYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIY----KLD 596
              + R +IF+ +KL   N+    V E AF  +L  LGLDY+DLYL+H P  +    + D
Sbjct: 72  AGNIAREEIFVTTKLWNTNHRPERV-EPAFEASLDRLGLDYLDLYLIHTPFAFQPGDEQD 130

Query: 597 FENRNSSRI------RKQTWATLVDLYHDHKIRALGVSN 695
             ++N S I       ++TW+ L +L    + RA+G+S+
Sbjct: 131 PRDQNGSVIYDEGVTLRETWSALENLVDRGRCRAIGLSD 169


>UniRef50_Q9Y020 Cluster: 3-dehydroecdysone 3beta-reductase
           precursor; n=1; Spodoptera littoralis|Rep:
           3-dehydroecdysone 3beta-reductase precursor - Spodoptera
           littoralis (Egyptian cotton leafworm)
          Length = 345

 Score = 75.4 bits (177), Expect = 4e-12
 Identities = 50/155 (32%), Positives = 79/155 (50%), Gaps = 8/155 (5%)
 Frame = +3

Query: 258 NGVEMPAIGLDT---FKMGHFYT-----VLQTVDDALKAGYRMFDTAALYGNEVYLNFAF 413
           N  EMPAI L T   F  G   T     +   V  A+  GYR FDTAA+Y  E  +  A 
Sbjct: 29  NDREMPAIALGTYLGFDKGGAVTSKDKQLRNVVMQAIDLGYRHFDTAAIYNTEAEVGEAI 88

Query: 414 KKLLPKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKL 593
           +  + +  +KR D+F+ +KL   ++    V   A   TL+  GLDY+DL+L+H P     
Sbjct: 89  RMKIDEGVIKREDVFLTTKLWNTHHKREQVAV-AMKETLNKTGLDYVDLFLMHWPIALNE 147

Query: 594 DFENRNSSRIRKQTWATLVDLYHDHKIRALGVSNY 698
           D+ + N+  +  +TW    ++      +++G+SN+
Sbjct: 148 DYSHSNTDYL--ETWRATEEMVKLGYTKSIGLSNF 180


>UniRef50_A2QVE5 Cluster: Similarity: shows similarity to several
           dehydrogenases of different specificities; n=4;
           Pezizomycotina|Rep: Similarity: shows similarity to
           several dehydrogenases of different specificities -
           Aspergillus niger
          Length = 381

 Score = 75.4 bits (177), Expect = 4e-12
 Identities = 48/116 (41%), Positives = 65/116 (56%), Gaps = 1/116 (0%)
 Frame = +3

Query: 234 LPQQFTLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAF 413
           L ++ TLN+G ++P +G  T++      V   V +ALKAGYR  D A +Y N+  +    
Sbjct: 3   LGKKVTLNSGAQIPQLGFGTWQSAPGQ-VGDAVYEALKAGYRHLDLATIYQNQREVAEGI 61

Query: 414 KKLLPKYK-LKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNP 578
           K+       LKR DIFI SKL    +   AV E+A    L+ L LDY+DLYLVH P
Sbjct: 62  KRAYKDVPGLKREDIFITSKLWNSQHDP-AVVEKALDECLAELELDYLDLYLVHWP 116


>UniRef50_P14550 Cluster: Alcohol dehydrogenase [NADP+]; n=44;
           Bilateria|Rep: Alcohol dehydrogenase [NADP+] - Homo
           sapiens (Human)
          Length = 325

 Score = 75.4 bits (177), Expect = 4e-12
 Identities = 58/159 (36%), Positives = 80/159 (50%), Gaps = 10/159 (6%)
 Frame = +3

Query: 252 LNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKK-LLP 428
           L+ G +MP IGL T+K      V   V  AL  GYR  D AA+YGNE  +  A K+ + P
Sbjct: 8   LHTGQKMPLIGLGTWK-SEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALKEDVGP 66

Query: 429 KYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVH---------NPG 581
              + R ++F+ SKL    +    V E A   TL++L L+Y+DLYL+H         NP 
Sbjct: 67  GKAVPREELFVTSKLWNTKHHPEDV-EPALRKTLADLQLEYLDLYLMHWPYAFERGDNPF 125

Query: 582 IYKLDFENRNSSRIRKQTWATLVDLYHDHKIRALGVSNY 698
               D      S   K+TW  L  L     ++ALG+SN+
Sbjct: 126 PKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNF 164


>UniRef50_Q96UH3 Cluster: Aldehyde reductase; n=13;
           Pezizomycotina|Rep: Aldehyde reductase - Coccidioides
           posadasii
          Length = 314

 Score = 74.9 bits (176), Expect = 5e-12
 Identities = 56/160 (35%), Positives = 82/160 (51%), Gaps = 9/160 (5%)
 Frame = +3

Query: 246 FTLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLL 425
           F LN G ++PAIG  T++  +       V  AL AGYR  DTAA+YG E     A  + L
Sbjct: 8   FRLNTGEDIPAIGFGTWQDENAQE--DAVLTALSAGYRHIDTAAVYGTEK----AIGRAL 61

Query: 426 PKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKL--DF 599
            + +L R ++FI SKL    +    V E+A   +L NL +DY+DLYL+H P  +    D 
Sbjct: 62  ARSRLSRDELFITSKLWNNKHRPEDV-EQAIDQSLKNLEIDYLDLYLMHWPAAFAPGDDM 120

Query: 600 ENRNSSRIRK-------QTWATLVDLYHDHKIRALGVSNY 698
             ++S    K        T+  +  L    K +A+G+SN+
Sbjct: 121 FPKDSQGNSKTVDIDYVDTYKAMEKLVKSGKTKAIGISNF 160


>UniRef50_Q5FKI1 Cluster: Reductase-dehydrogenase; n=1;
           Lactobacillus acidophilus|Rep: Reductase-dehydrogenase -
           Lactobacillus acidophilus
          Length = 271

 Score = 74.5 bits (175), Expect = 7e-12
 Identities = 50/150 (33%), Positives = 80/150 (53%), Gaps = 1/150 (0%)
 Frame = +3

Query: 252 LNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPK 431
           LNNG ++P I L T+ + +   V + V  A+  GYR FDTA  YGNE  +     K +  
Sbjct: 9   LNNGEKIPQIQLGTWLINND-EVNKVVRQAVNIGYRGFDTAKDYGNESGVG----KGIWN 63

Query: 432 YKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIY-KLDFENR 608
             ++R DIF+ +KL P        T++A    L   GL+YIDL L+H+P  + +++  N 
Sbjct: 64  SDIERSDIFLTTKL-PTAVKDYEGTKKAIDAALDKFGLEYIDLLLIHSPQPWIEVNRTND 122

Query: 609 NSSRIRKQTWATLVDLYHDHKIRALGVSNY 698
              +   + W  + +     K+R++GVSN+
Sbjct: 123 RHFKGNLENWRAMEEAVKAGKVRSIGVSNF 152


>UniRef50_Q11BF8 Cluster: Aldo/keto reductase; n=12; Bacteria|Rep:
           Aldo/keto reductase - Mesorhizobium sp. (strain BNC1)
          Length = 308

 Score = 74.5 bits (175), Expect = 7e-12
 Identities = 55/147 (37%), Positives = 75/147 (51%)
 Frame = +3

Query: 258 NGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPKYK 437
           +GVEMP IGL  F+     T    V++AL+ GYR  DTAA YGNE  +    ++      
Sbjct: 25  SGVEMPMIGLGVFQTPPDETTA-AVEEALRLGYRHIDTAAAYGNEREVGEGIRRA----G 79

Query: 438 LKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLDFENRNSS 617
           + R ++FI +K+   +YG    T  AF  +   LG+D IDL L+H P     D   R   
Sbjct: 80  IARDEVFIETKIWISDYGYDE-TLHAFDKSAGKLGVDQIDLLLLHQPLPSAFD---RTLG 135

Query: 618 RIRKQTWATLVDLYHDHKIRALGVSNY 698
             R      L  L  D K+RA+GVSN+
Sbjct: 136 AYR-----ALEKLLADGKVRAIGVSNF 157


>UniRef50_Q03X85 Cluster: Aldo/keto reductase of diketogulonate
           reductase family; n=1; Leuconostoc mesenteroides subsp.
           mesenteroides ATCC 8293|Rep: Aldo/keto reductase of
           diketogulonate reductase family - Leuconostoc
           mesenteroides subsp. mesenteroides (strain ATCC 8293
           /NCDO 523)
          Length = 288

 Score = 74.5 bits (175), Expect = 7e-12
 Identities = 48/153 (31%), Positives = 76/153 (49%), Gaps = 2/153 (1%)
 Frame = +3

Query: 249 TLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLP 428
           TLNNG +MP +G   F++    T  Q V DA+ AGYR  DTA +YGNE        + + 
Sbjct: 5   TLNNGAQMPQLGFGVFQIPAEETK-QAVVDAINAGYRSIDTARVYGNEAETGQGVNEAIA 63

Query: 429 KYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNP--GIYKLDFE 602
              + R ++F+ +KL    +   A  + A  ++L  LG DY DL L+H P   +Y     
Sbjct: 64  NAVVAREELFLTTKLWLSEFSYEA-AKGAIDDSLKKLGTDYADLILLHQPYGDVY----- 117

Query: 603 NRNSSRIRKQTWATLVDLYHDHKIRALGVSNYF 701
                      +  L +   D K++++G+SN++
Sbjct: 118 ---------GAYKALAEAQADGKVKSIGISNFY 141


>UniRef50_A7SIT3 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 323

 Score = 74.5 bits (175), Expect = 7e-12
 Identities = 53/160 (33%), Positives = 79/160 (49%), Gaps = 9/160 (5%)
 Frame = +3

Query: 252 LNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPK 431
           LN G  +PA+ L T++      V   V  A++ GYR  D A +YGNE  +  A  ++L +
Sbjct: 10  LNTGASIPAMALGTWQSSK-EEVGNAVRLAIELGYRHIDCAEIYGNEGEIGEALSEVLTE 68

Query: 432 YKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLDFENRN 611
            K+KR ++F+ SKL  C+         A   TL NL LDY+DLYL+H P  +K      +
Sbjct: 69  GKVKREELFVTSKLW-CDSHHPDDVLPACQATLKNLQLDYLDLYLIHIPVAFKKGVRLPH 127

Query: 612 S---------SRIRKQTWATLVDLYHDHKIRALGVSNYFI 704
           S             + TW  +  L      +A+GVSN+ +
Sbjct: 128 SIAEGIIGYTPEGVQNTWQAMEGLVAKGLCKAIGVSNFSV 167


>UniRef50_Q6C2L0 Cluster: Yarrowia lipolytica chromosome F of strain
           CLIB122 of Yarrowia lipolytica; n=3; Yarrowia
           lipolytica|Rep: Yarrowia lipolytica chromosome F of
           strain CLIB122 of Yarrowia lipolytica - Yarrowia
           lipolytica (Candida lipolytica)
          Length = 324

 Score = 74.1 bits (174), Expect = 9e-12
 Identities = 44/115 (38%), Positives = 68/115 (59%)
 Frame = +3

Query: 234 LPQQFTLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAF 413
           +   F LN+G  +PA+GL T   G+   V + V  A+K GYR  DTA +YG+EV +    
Sbjct: 3   ITDSFKLNDGHSIPALGLGTASDGN---VEEVVYAAIKNGYRHIDTAFIYGSEVDVGKGI 59

Query: 414 KKLLPKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNP 578
           K+ + +  +KR ++F+ +K+ P  Y    V+E +   +L +L LDY+DL LVH P
Sbjct: 60  KRAIDEELVKRENLFVTTKVWPTFY--NRVSE-SLDISLKDLSLDYVDLLLVHWP 111


>UniRef50_UPI00015B4B22 Cluster: PREDICTED: similar to GA15457-PA;
           n=1; Nasonia vitripennis|Rep: PREDICTED: similar to
           GA15457-PA - Nasonia vitripennis
          Length = 388

 Score = 73.7 bits (173), Expect = 1e-11
 Identities = 53/164 (32%), Positives = 81/164 (49%), Gaps = 11/164 (6%)
 Frame = +3

Query: 240 QQFTLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKK 419
           ++  L++G E+PA+GL T  +     +   +  AL+ GYR  DTA  Y NE  +    KK
Sbjct: 24  EKLKLSSGHEIPAVGLGTSTI-KLDEMDNAISSALENGYRHIDTAFSYDNEAAIGKILKK 82

Query: 420 LLPKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLDF 599
              K   KR DIFI SKL P         E     +L +LGLDY+D+YL+H P   K + 
Sbjct: 83  WFDKGG-KREDIFITSKL-PSQGNRPQSVETYLKRSLKDLGLDYVDMYLIHTPFAVK-EG 139

Query: 600 ENRNSSRIR-----------KQTWATLVDLYHDHKIRALGVSNY 698
           EN +S + +           K  W  +     + + +++G+SN+
Sbjct: 140 ENLSSKQDKDGNDLFDDVDHKALWKAMERQVKEGRAKSIGLSNF 183


>UniRef50_Q8EUH6 Cluster: Oxidoreductase; n=1; Mycoplasma
           penetrans|Rep: Oxidoreductase - Mycoplasma penetrans
          Length = 285

 Score = 73.7 bits (173), Expect = 1e-11
 Identities = 56/152 (36%), Positives = 79/152 (51%), Gaps = 3/152 (1%)
 Frame = +3

Query: 252 LNNGVEMPAIGLDTFKM---GHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKL 422
           L NG+ MP IGL  +K        T+++ +DD    GYRM DTA +Y NE ++  A K+ 
Sbjct: 6   LANGLHMPIIGLGVYKAEGENCENTIIKAIDDY---GYRMIDTAQVYFNEEFVGNAIKQT 62

Query: 423 LPKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLDFE 602
               K+KR DIFI +K+   NYG    T  +   +L  L  +YIDL L+H P      F 
Sbjct: 63  ----KIKREDIFITTKVWISNYGYNN-TMYSISKSLKKLQTNYIDLVLLHQP------FG 111

Query: 603 NRNSSRIRKQTWATLVDLYHDHKIRALGVSNY 698
           +  S+      W  L  LY    ++A+GVSN+
Sbjct: 112 DYYSA------WKALEVLYKKGIVKAIGVSNF 137


>UniRef50_Q17DN0 Cluster: Aldo-keto reductase; n=5; Culicidae|Rep:
           Aldo-keto reductase - Aedes aegypti (Yellowfever
           mosquito)
          Length = 324

 Score = 73.7 bits (173), Expect = 1e-11
 Identities = 54/162 (33%), Positives = 80/162 (49%), Gaps = 13/162 (8%)
 Frame = +3

Query: 252 LNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPK 431
           LNNG+EMPAIGL T  M       + V  A+  G+R  DTA  Y NE  +  A +  + +
Sbjct: 11  LNNGLEMPAIGLGT-SMSKGDECCKAVMTAIDEGFRHIDTAYNYRNEDVVGRAIRAKIEE 69

Query: 432 YKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKL---DFE 602
             + R ++F+ +KL    +    V   AF  +L +LGLDY+DL+L+H P  Y+    D E
Sbjct: 70  GVVTREELFVTTKLWNTFHHPDHVP-MAFGKSLEHLGLDYVDLFLIHMPFGYEFNGWDPE 128

Query: 603 NRN----------SSRIRKQTWATLVDLYHDHKIRALGVSNY 698
            R           S      TW  +  L    ++ ++GVSN+
Sbjct: 129 KRTPLDDNGNVLCSDDDYVDTWKAMEKLLESGRVHSIGVSNF 170


>UniRef50_Q929C8 Cluster: Lin2349 protein; n=12; Listeria|Rep:
           Lin2349 protein - Listeria innocua
          Length = 294

 Score = 73.3 bits (172), Expect = 2e-11
 Identities = 50/155 (32%), Positives = 79/155 (50%)
 Frame = +3

Query: 234 LPQQFTLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAF 413
           L  +  L     +P IGL  F++     +   V+ A++ GYR+FDTAA+Y NE  +  A 
Sbjct: 5   LQDRMILPGNETIPYIGLGVFQVTEQEFIAGAVEKAIEVGYRLFDTAAVYNNEAIVGQA- 63

Query: 414 KKLLPKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKL 593
              +    + R ++FI SK+   + G    T  AF  TL NL LDY+DLYL+H P   K 
Sbjct: 64  ---ILDSAVPREELFISSKVWNGDLGYDE-TLFAFERTLRNLKLDYLDLYLIHWPVAGKY 119

Query: 594 DFENRNSSRIRKQTWATLVDLYHDHKIRALGVSNY 698
                      + +W  +  L+ +  I+++GV+N+
Sbjct: 120 -----------RDSWRAMERLHDEKLIKSIGVANF 143


>UniRef50_Q3CZS2 Cluster: Oxidoreductase, aldo/keto reductase
           family; n=2; Streptococcus agalactiae|Rep:
           Oxidoreductase, aldo/keto reductase family -
           Streptococcus agalactiae H36B
          Length = 245

 Score = 73.3 bits (172), Expect = 2e-11
 Identities = 45/115 (39%), Positives = 63/115 (54%)
 Frame = +3

Query: 234 LPQQFTLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAF 413
           L Q F LNNGV++P++G   F++       Q+V DAL+ GYR+ DTA+ Y NE  +  A 
Sbjct: 3   LNQFFILNNGVKIPSLGFGVFQIDDPLECEQSVLDALQVGYRLIDTASGYLNEEAVGRAI 62

Query: 414 KKLLPKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNP 578
           K    K  + R +IF+++KL             A    L  L LDYI+LYL+H P
Sbjct: 63  K----KSGIPRKEIFVVTKLW-IQDASEEKAGPAIDRALKRLQLDYINLYLIHQP 112


>UniRef50_Q03U37 Cluster: Aldo/keto reductase of diketogulonate
           reductase family; n=5; Lactobacillus|Rep: Aldo/keto
           reductase of diketogulonate reductase family -
           Lactobacillus brevis (strain ATCC 367 / JCM 1170)
          Length = 282

 Score = 73.3 bits (172), Expect = 2e-11
 Identities = 53/151 (35%), Positives = 77/151 (50%)
 Frame = +3

Query: 252 LNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPK 431
           L +G +MP +G  T+ +    T+   +  A  AGYRMFDTA LY NE  L  A ++L   
Sbjct: 12  LADGRQMPVMGFGTYLLNDQPTMNTAIQTAWDAGYRMFDTAMLYRNEDILGPAIQQL--- 68

Query: 432 YKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLDFENRN 611
             L R  +F+ SK+     G    T +A   +L  L  DY+DL L+H P + +  F+   
Sbjct: 69  -GLPREGLFLTSKVAEIVQGYDQ-TMKAVEGSLKRLQTDYLDLLLIHWP-VREHFFD--- 122

Query: 612 SSRIRKQTWATLVDLYHDHKIRALGVSNYFI 704
                  TW  L  L  D +++++GVSNY I
Sbjct: 123 -------TWRALEQLKADGQVKSIGVSNYTI 146


>UniRef50_Q927P9 Cluster: Lin2739 protein; n=12; Bacteria|Rep:
           Lin2739 protein - Listeria innocua
          Length = 283

 Score = 72.9 bits (171), Expect = 2e-11
 Identities = 51/149 (34%), Positives = 75/149 (50%)
 Frame = +3

Query: 252 LNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPK 431
           LNNG+E+P +G  T+++       Q V +A+ AGYR  DTA  Y NE     A  + +  
Sbjct: 6   LNNGIEVPILGFGTYQITDAGEAEQAVKEAIAAGYRHIDTAQSYMNEE----AVGRGIAA 61

Query: 432 YKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLDFENRN 611
             + R ++FI +K+   N     V   +F  +L  LGLDYIDL L+H P  Y   +    
Sbjct: 62  SGVDRKELFITTKIWVENVSYKGVMS-SFDRSLKRLGLDYIDLLLIHQP--YNDVY---- 114

Query: 612 SSRIRKQTWATLVDLYHDHKIRALGVSNY 698
                   W  + +L    KI+A+GVSN+
Sbjct: 115 ------GAWMAMEELQAQGKIKAIGVSNF 137


>UniRef50_Q043M4 Cluster: Aldo/keto reductase of diketogulonate
           reductase family; n=2; Lactobacillus|Rep: Aldo/keto
           reductase of diketogulonate reductase family -
           Lactobacillus gasseri (strain ATCC 33323 / DSM 20243)
          Length = 273

 Score = 72.9 bits (171), Expect = 2e-11
 Identities = 52/153 (33%), Positives = 74/153 (48%)
 Frame = +3

Query: 240 QQFTLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKK 419
           +Q TLNN V++P  G  T+++    T  Q V  A + GYR+ DTA  Y NE  +  A K 
Sbjct: 2   KQLTLNNDVKIPIFGFGTYEISPDQTK-QAVLSAFEEGYRLIDTAQYYQNEQQVGEAVK- 59

Query: 420 LLPKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLDF 599
                 L R ++FI +K +   Y     T+     +L  +GLDY DL L+H P  + +D 
Sbjct: 60  ---ASGLNRDEVFITTKTMTDGYED---TKIGLDESLRRIGLDYFDLVLIHWPMGHDID- 112

Query: 600 ENRNSSRIRKQTWATLVDLYHDHKIRALGVSNY 698
                      TW  L   Y   K RA+G+SN+
Sbjct: 113 -----------TWHALEAAYKAGKTRAIGISNF 134


>UniRef50_P27800 Cluster: Aldehyde reductase 1; n=18; root|Rep:
           Aldehyde reductase 1 - Sporobolomyces salmonicolor
          Length = 323

 Score = 72.9 bits (171), Expect = 2e-11
 Identities = 54/164 (32%), Positives = 81/164 (49%), Gaps = 14/164 (8%)
 Frame = +3

Query: 249 TLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLP 428
           TLN G  +  +G  T++      V Q V  A++ GYR  D A +Y N+  +  A K+   
Sbjct: 6   TLNTGASLELVGYGTWQAAPG-EVGQGVKVAIETGYRHLDLAKVYSNQPEVGAAIKEA-- 62

Query: 429 KYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLD---- 596
              +KR D+FI SKL   ++    V E A  +TL  LGL+Y+DLYL+H P  +  +    
Sbjct: 63  --GVKREDLFITSKLWNNSHRPEQV-EPALDDTLKELGLEYLDLYLIHWPVAFPPEGDIT 119

Query: 597 ---FENRNSSRIR-------KQTWATLVDLYHDHKIRALGVSNY 698
              F   N   ++         TW  +V L    K++A+GVSN+
Sbjct: 120 QNLFPKANDKEVKLDLEVSLVDTWKAMVKLLDTGKVKAIGVSNF 163


>UniRef50_Q14LU6 Cluster: Putative aldo/keto reductase
           oxidoreductase protein; n=1; Spiroplasma citri|Rep:
           Putative aldo/keto reductase oxidoreductase protein -
           Spiroplasma citri
          Length = 138

 Score = 72.5 bits (170), Expect = 3e-11
 Identities = 45/112 (40%), Positives = 60/112 (53%)
 Frame = +3

Query: 234 LPQQFTLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAF 413
           L  +  L NGVE+P IGL T+KM   + V Q +  AL+ GYR  DTA +YGNE  +  A 
Sbjct: 4   LTTKLKLFNGVEIPLIGLGTYKMTDEHEVYQAIITALQNGYRHIDTAQIYGNEELIGKAI 63

Query: 414 KKLLPKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLV 569
           K       + R +IF+ SK+   N+   A  +    N L  L  DY+DL LV
Sbjct: 64  K----DSGVPRKEIFLTSKIWNANHKYDAALQE-IDNILKRLDTDYLDLCLV 110


>UniRef50_Q41399 Cluster: Chalcone reductase; n=4;
           eudicotyledons|Rep: Chalcone reductase - Sesbania
           rostrata
          Length = 322

 Score = 72.5 bits (170), Expect = 3e-11
 Identities = 50/159 (31%), Positives = 83/159 (52%), Gaps = 10/159 (6%)
 Frame = +3

Query: 252 LNNGVEMPAIGLDT-FKMGHFYTVLQTVD-DALKAGYRMFDTAALYGNEVYLNFAFKKLL 425
           LN+G +MP IG+ T  +      VL ++  DA++ GYR FD+A++YG E  +  A  K +
Sbjct: 11  LNSGHKMPVIGMGTSVESRPSNDVLASIFVDAIQVGYRHFDSASVYGTEEAIGMAVSKAI 70

Query: 426 PKYKLK-RGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLDFE 602
            +  +K R ++FI SK    +     +   A   TL  LG++Y+DLYL+H P   + D E
Sbjct: 71  EQGLIKSRDEVFITSKPWNTDAHHDLIVP-ALKTTLKKLGMEYVDLYLIHWPVRLRHDLE 129

Query: 603 NR---NSSRIR----KQTWATLVDLYHDHKIRALGVSNY 698
           N    +   +     + TW  + + Y     +++G+ NY
Sbjct: 130 NPVIFSKEDLLPFDIEGTWKAMEECYRLGLAKSIGICNY 168


>UniRef50_Q6CFG7 Cluster: Yarrowia lipolytica chromosome B of strain
           CLIB122 of Yarrowia lipolytica; n=9; Ascomycota|Rep:
           Yarrowia lipolytica chromosome B of strain CLIB122 of
           Yarrowia lipolytica - Yarrowia lipolytica (Candida
           lipolytica)
          Length = 337

 Score = 72.5 bits (170), Expect = 3e-11
 Identities = 57/166 (34%), Positives = 84/166 (50%), Gaps = 13/166 (7%)
 Frame = +3

Query: 246 FTLNNGVEMPAIGLDTFKMGHFYTVLQTVDDAL-KAGYRMFDTAALYGNEVYLNFAFKKL 422
           FTLNNG  +PAIGL T+K      V   V+ AL + GYR  DTA  Y NE  +    K+ 
Sbjct: 34  FTLNNGKTIPAIGLGTWK-STTEEVAGAVECALTEGGYRHIDTAFNYRNEDAVGLGIKRA 92

Query: 423 LPKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVH-----NPG-- 581
           + K  +KR DIF+ +K+    +      E     +L  LGLDY+D+ L+H     NP   
Sbjct: 93  MEK-GVKREDIFVTTKIWVTYHDR---VEENLDMSLERLGLDYVDMLLIHWPVPLNPNGN 148

Query: 582 --IYKL---DFENRNSSRIRKQTWATLVDLYHDHKIRALGVSNYFI 704
             +Y L      + + S  + +TW  +  +    K +++GVSN+ I
Sbjct: 149 DPVYPLRPDGSRDIDESGSQPKTWKQMEAVLKTGKTKSIGVSNFSI 194


>UniRef50_A4YQ04 Cluster: 2,5-diketo-D-gluconate reductase B; n=15;
           Proteobacteria|Rep: 2,5-diketo-D-gluconate reductase B -
           Bradyrhizobium sp. (strain ORS278)
          Length = 273

 Score = 72.1 bits (169), Expect = 3e-11
 Identities = 51/149 (34%), Positives = 77/149 (51%), Gaps = 1/149 (0%)
 Frame = +3

Query: 261 GVEMPAIGLDTFKMGHFYTVLQ-TVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPKYK 437
           GV +P +GL TF+M    TV +  V+ AL  GYR  DTA +Y NE  +  A    L   +
Sbjct: 8   GVRLPKLGLGTFRMQG--TVCRDAVESALALGYRHIDTAEMYANEDAIGAA----LAAAQ 61

Query: 438 LKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLDFENRNSS 617
           + R D+ + +K+ P N    A+  RAF  +L  L LD++DLYL+H P           + 
Sbjct: 62  IAREDLHVTTKVWPENLAPDAI-RRAFDTSLKKLRLDFVDLYLIHWPA----------TG 110

Query: 618 RIRKQTWATLVDLYHDHKIRALGVSNYFI 704
                   TL+ L  + + RA+GV+N+ +
Sbjct: 111 MNLPAAMETLMALKQEGRTRAIGVANFTV 139


>UniRef50_A1UEC5 Cluster: 2,5-didehydrogluconate reductase; n=20;
           Corynebacterineae|Rep: 2,5-didehydrogluconate reductase
           - Mycobacterium sp. (strain KMS)
          Length = 283

 Score = 72.1 bits (169), Expect = 3e-11
 Identities = 49/150 (32%), Positives = 79/150 (52%)
 Frame = +3

Query: 249 TLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLP 428
           +LN+G  +P +GL   ++       ++V  AL+AGYR+ DTAA+YGNE     A  + + 
Sbjct: 15  SLNDGHSIPVLGLGVGELSEAEAE-RSVAAALEAGYRLIDTAAVYGNEA----AVGRAVN 69

Query: 429 KYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLDFENR 608
              + R +I++ +KL   + G G  ++ A   +L  LGLDY+DLYL+H P          
Sbjct: 70  ASGIPREEIYVTTKLAVADQGFG-TSQDAARASLERLGLDYVDLYLIHWPA-------GD 121

Query: 609 NSSRIRKQTWATLVDLYHDHKIRALGVSNY 698
           +   I   +W  L+    D   R++GV N+
Sbjct: 122 HGKYI--DSWGGLMKAKQDGVARSIGVCNF 149


>UniRef50_Q5KI95 Cluster: Aldo-keto reductase, putative; n=14;
           Dikarya|Rep: Aldo-keto reductase, putative -
           Cryptococcus neoformans (Filobasidiella neoformans)
          Length = 353

 Score = 72.1 bits (169), Expect = 3e-11
 Identities = 57/165 (34%), Positives = 78/165 (47%), Gaps = 12/165 (7%)
 Frame = +3

Query: 237 PQQFTLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFK 416
           P  F LN G  +PAIGL T++      V Q V  ALKAGYR  D A  Y NE  +    K
Sbjct: 36  PTSFKLNTGASIPAIGLGTWQ-AKAGEVRQAVAHALKAGYRHIDGALCYQNEDEVGLGIK 94

Query: 417 KLLPKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNP------ 578
                  + R +IF+ SK+    +      E     TL +L  DY+DLYL+H P      
Sbjct: 95  DS----GVPRSEIFLTSKVWSSYHDR---VEECLDTTLKSLQTDYLDLYLIHWPVRLAPN 147

Query: 579 GIYKLDFENRNSSR------IRKQTWATLVDLYHDHKIRALGVSN 695
           G + L     + SR       + +TWA + D+    K +A+G+SN
Sbjct: 148 GTHPLFPVKPDGSRNLDWDWDQAKTWAQMEDVLKKGKAKAIGLSN 192


>UniRef50_UPI00015B40FA Cluster: PREDICTED: similar to CG2767-PA;
           n=2; Nasonia vitripennis|Rep: PREDICTED: similar to
           CG2767-PA - Nasonia vitripennis
          Length = 356

 Score = 71.7 bits (168), Expect = 5e-11
 Identities = 45/115 (39%), Positives = 63/115 (54%)
 Frame = +3

Query: 252 LNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPK 431
           L++G +MP IGL T++M     +   V  AL++GYR  DTA  YGNE  +    KK   K
Sbjct: 30  LSSGHDMPMIGLGTWQMPP-EAIEVAVTAALESGYRHIDTAFTYGNEEAIGKTLKKWFDK 88

Query: 432 YKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLD 596
              KR D+FI +KL P       V E     +L  LGL+Y+++YL+H P  +  D
Sbjct: 89  GG-KREDLFITTKLPPIGMRAEYV-ESYLKLSLEKLGLEYVNMYLIHKPFAFVKD 141


>UniRef50_Q1YPE5 Cluster: Aldehyde reductase; n=7; Bacteria|Rep:
           Aldehyde reductase - gamma proteobacterium HTCC2207
          Length = 330

 Score = 71.7 bits (168), Expect = 5e-11
 Identities = 43/114 (37%), Positives = 64/114 (56%), Gaps = 1/114 (0%)
 Frame = +3

Query: 270 MPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPKYKLKRG 449
           MPA+GL  +K+    +  Q V +A+K GYR  D+AA YGNE  +     + + +    R 
Sbjct: 17  MPAVGLGLWKITQD-SAAQAVYEAIKVGYRHLDSAADYGNEQQVGEGIARAIAEGLCSRE 75

Query: 450 DIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNP-GIYKLDFENR 608
           +++I +KL    Y      E A   ++ +LGLDYIDLYLVH P  +  +DF +R
Sbjct: 76  ELWITTKLWN-TYHRAEHVEAACRRSMDDLGLDYIDLYLVHFPIALRYVDFNDR 128


>UniRef50_A0JRJ3 Cluster: 2,5-didehydrogluconate reductase; n=3;
           Actinobacteria (class)|Rep: 2,5-didehydrogluconate
           reductase - Arthrobacter sp. (strain FB24)
          Length = 276

 Score = 71.7 bits (168), Expect = 5e-11
 Identities = 51/149 (34%), Positives = 75/149 (50%)
 Frame = +3

Query: 252 LNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPK 431
           LN+G  +P IGL T+ +   + V   V +A++ GYR  DTA  YGNE  +    +     
Sbjct: 9   LNDGHRIPQIGLGTWPLDD-HQVAAAVVNAVEGGYRHIDTAVKYGNEKGVGNGIR----S 63

Query: 432 YKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLDFENRN 611
             L R ++FI +K L   + G          +L  LGLDY+DL L+H P   + +F +  
Sbjct: 64  SGLDRSELFITTK-LDGEFQGQDRAVAGLDGSLKRLGLDYVDLLLIHWPLPRRDEFIS-- 120

Query: 612 SSRIRKQTWATLVDLYHDHKIRALGVSNY 698
                  TW T   L  D K+R++GVSN+
Sbjct: 121 -------TWKTFERLQADGKVRSIGVSNF 142


>UniRef50_A7RRF6 Cluster: Predicted protein; n=2; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 275

 Score = 71.3 bits (167), Expect = 6e-11
 Identities = 40/110 (36%), Positives = 67/110 (60%)
 Frame = +3

Query: 249 TLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLP 428
           TL++G ++P  GL  + +   +T  Q V  AL+ GYRM DTAA Y NE  +  A ++   
Sbjct: 8   TLSDGYKIPRFGLGLYDLDEKHTK-QAVLWALENGYRMIDTAASYNNEKRVGEALRESA- 65

Query: 429 KYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNP 578
              + R ++++++K+   ++G    T +A+  +LS LG+DY+DLYL+H P
Sbjct: 66  ---VPRSEVYLVTKVYHTDHGYEK-TMKAYDRSLSALGVDYVDLYLIHFP 111


>UniRef50_P28475 Cluster: NADP-dependent D-sorbitol-6-phosphate
           dehydrogenase; n=71; Magnoliophyta|Rep: NADP-dependent
           D-sorbitol-6-phosphate dehydrogenase - Malus domestica
           (Apple) (Malus sylvestris)
          Length = 310

 Score = 70.9 bits (166), Expect = 8e-11
 Identities = 53/163 (32%), Positives = 84/163 (51%), Gaps = 13/163 (7%)
 Frame = +3

Query: 249 TLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLP 428
           TL++G EMP IGL  +++     + + + +A+K GYR FD AA Y +E  +  A  +   
Sbjct: 5   TLSSGYEMPVIGLGLWRLEKD-ELKEVILNAIKIGYRHFDCAAHYKSEADVGEALAEAFK 63

Query: 429 KYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLDFENR 608
              +KR ++FI +K+   N   G V E A  N+L  L +DY+DLYLVH P   K +   +
Sbjct: 64  TGLVKREELFITTKI--WNSDHGHVVE-ACKNSLEKLQIDYLDLYLVHYPMPTKHNAIGK 120

Query: 609 NSSRI-------------RKQTWATLVDLYHDHKIRALGVSNY 698
            +S +              +QTW  +        +R++G+SNY
Sbjct: 121 TASLLGEDKVLDIDVTISLQQTWEGMEKTVSLGLVRSIGLSNY 163


>UniRef50_P23901 Cluster: Aldose reductase; n=9; Poaceae|Rep: Aldose
           reductase - Hordeum vulgare (Barley)
          Length = 320

 Score = 70.9 bits (166), Expect = 8e-11
 Identities = 53/159 (33%), Positives = 77/159 (48%), Gaps = 6/159 (3%)
 Frame = +3

Query: 246 FTLNNGVEMPAIGLDTFKMGHFYTVLQTVDDAL-KAGYRMFDTAALYGNEVYLNFAFKKL 422
           F L +G  MPA+GL T++ G       +V  A+ +AGYR  DTAA YG E  +    K  
Sbjct: 16  FVLKSGHAMPAVGLGTWRAGS--DTAHSVRTAITEAGYRHVDTAAEYGVEKEVGKGLKAA 73

Query: 423 LPKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNP-----GIY 587
           + +  + R D+F+ SK+   N     V   A  NTL +L LDYIDLY +H P     G +
Sbjct: 74  M-EAGIDRKDLFVTSKIWCTNLAPERVRP-ALENTLKDLQLDYIDLYHIHWPFRLKDGAH 131

Query: 588 KLDFENRNSSRIRKQTWATLVDLYHDHKIRALGVSNYFI 704
                        +  W  + +L  D  ++ +GV NY +
Sbjct: 132 MPPEAGEVLEFDMEGVWKEMENLVKDGLVKDIGVCNYTV 170


>UniRef50_Q5KCN9 Cluster: Putative uncharacterized protein; n=1;
           Filobasidiella neoformans|Rep: Putative uncharacterized
           protein - Cryptococcus neoformans (Filobasidiella
           neoformans)
          Length = 295

 Score = 70.1 bits (164), Expect = 1e-10
 Identities = 47/155 (30%), Positives = 80/155 (51%), Gaps = 5/155 (3%)
 Frame = +3

Query: 249 TLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLP 428
           TLN+GV++P IG       +    ++ +  ALK GY   D A +Y N    + + K  L 
Sbjct: 7   TLNDGVKIPKIGFGLGTTHYAKECVEHLVSALKTGYTYIDCAQMYKN----SKSVKDALE 62

Query: 429 KYKLKRGDIFIISKLLPCNYGGG-AVTER----AFHNTLSNLGLDYIDLYLVHNPGIYKL 593
           K+  KR DIF++ K   C  GGG + +E+         L  +G+DY+DLYL+H+P ++  
Sbjct: 63  KWGGKREDIFLLQK---CGSGGGDSESEKNPKVILKGLLQEMGVDYVDLYLLHSPLLFAP 119

Query: 594 DFENRNSSRIRKQTWATLVDLYHDHKIRALGVSNY 698
            +          + WA + ++  +   +++GVSN+
Sbjct: 120 KYS-------INEAWAIMEEIKSEGLAKSIGVSNF 147


>UniRef50_A2QL02 Cluster: Putative frameshift; n=1; Aspergillus
           niger|Rep: Putative frameshift - Aspergillus niger
          Length = 357

 Score = 70.1 bits (164), Expect = 1e-10
 Identities = 54/160 (33%), Positives = 80/160 (50%), Gaps = 9/160 (5%)
 Frame = +3

Query: 246 FTLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLL 425
           +TLN G ++PA+G+ TF+        +TV   L+ G R+ DTA +YG E  +    K   
Sbjct: 38  YTLNTGAKIPALGVGTFQDPDSQE--ETVCQVLQRGMRLIDTARVYGVEQQVGRGIK--- 92

Query: 426 PKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYK----- 590
            K  + R +IF+ +KL  CN       ERA  ++L +L   Y+DL L+H P  +K     
Sbjct: 93  -KSGVPREEIFLGTKLW-CNDFHPDDVERAVDDSLRDLYTPYVDLLLMHYPCTFKRGEDR 150

Query: 591 --LDFENR--NSSRIRKQTWATLVDLYHDHKIRALGVSNY 698
              D E R  +       TW  L  +    K+RA+GVSN+
Sbjct: 151 FPRDAEGRMIHGETTFVDTWRALEKVVKTGKVRAIGVSNF 190


>UniRef50_UPI0000E4A7CE Cluster: PREDICTED: similar to LOC553452
           protein; n=6; Strongylocentrotus purpuratus|Rep:
           PREDICTED: similar to LOC553452 protein -
           Strongylocentrotus purpuratus
          Length = 321

 Score = 69.7 bits (163), Expect = 2e-10
 Identities = 49/161 (30%), Positives = 81/161 (50%), Gaps = 10/161 (6%)
 Frame = +3

Query: 252 LNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPK 431
           L  G ++P +G  T+++     V + ++ A+  GYR  D A+LYGNE  +    K  +  
Sbjct: 10  LPGGRKLPLLGFGTWQIKP-EEVGRVIETAIDCGYRHIDEASLYGNEKGVGDGIKAKIDD 68

Query: 432 YKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNP-------GIYK 590
             +KR D+F+ SKL   +     V E +   +LS+LGL Y+DL+L+H P       G + 
Sbjct: 69  GTIKREDLFVTSKLWVTDSHPSRV-EPSCRQSLSDLGLAYLDLFLIHCPTSAVGGKGPFP 127

Query: 591 LDFEN---RNSSRIRKQTWATLVDLYHDHKIRALGVSNYFI 704
           +D       + +     TW  +  L     +RA+GVSN+ +
Sbjct: 128 MDDNGLFIGDDTIDYVDTWRIMESLVDKGLVRAIGVSNFTV 168


>UniRef50_UPI000023D0F1 Cluster: hypothetical protein FG03517.1;
           n=1; Gibberella zeae PH-1|Rep: hypothetical protein
           FG03517.1 - Gibberella zeae PH-1
          Length = 364

 Score = 69.7 bits (163), Expect = 2e-10
 Identities = 46/153 (30%), Positives = 79/153 (51%), Gaps = 1/153 (0%)
 Frame = +3

Query: 243 QFTLNNGV-EMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKK 419
           +F  N  V ++PA GL T+  G    V+  V+ ALK GYR  DTA ++ NE  +    K 
Sbjct: 50  EFNKNETVRDIPAFGLGTWLAGKG-VVVPAVEYALKGGYRHIDTALIWRNEDEVGKGIKA 108

Query: 420 LLPKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLDF 599
                 + R +I++  KL   ++    V  +A   +++NLG++Y+DLYL+H P  +  + 
Sbjct: 109 S----GVSRDEIWVTGKLWNTDHRPELV-RKAIETSIANLGVEYLDLYLIHYPVAWVPET 163

Query: 600 ENRNSSRIRKQTWATLVDLYHDHKIRALGVSNY 698
            + +++     TW  + +L      R +G SN+
Sbjct: 164 RDVDNNTSLIDTWKAMEELVRAGLTRNIGFSNF 196


>UniRef50_A3U9Y0 Cluster: Aldehyde reductase; n=5;
           Bacteroidetes|Rep: Aldehyde reductase - Croceibacter
           atlanticus HTCC2559
          Length = 316

 Score = 69.7 bits (163), Expect = 2e-10
 Identities = 45/111 (40%), Positives = 61/111 (54%)
 Frame = +3

Query: 258 NGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPKYK 437
           +G  +P+IGL T+K      V + V  AL+ GY+  D AA Y NE  +  AFK+      
Sbjct: 8   DGDSIPSIGLGTWKSDP-EDVKKAVKIALENGYKHIDCAAAYDNEDAVGEAFKESFESGN 66

Query: 438 LKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYK 590
           +KR DIF+ SKL    +    V   A   TL +L LDY+DLYL+H P  +K
Sbjct: 67  VKREDIFVTSKLWNNAHKKEDVIP-ALKKTLKDLNLDYLDLYLMHWPVAFK 116


>UniRef50_Q9NAI5 Cluster: Putative uncharacterized protein; n=3;
           Caenorhabditis|Rep: Putative uncharacterized protein -
           Caenorhabditis elegans
          Length = 316

 Score = 69.7 bits (163), Expect = 2e-10
 Identities = 53/164 (32%), Positives = 81/164 (49%), Gaps = 11/164 (6%)
 Frame = +3

Query: 240 QQFTLNNGVEMPAIGLDTF--KMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAF 413
           Q   LN+G  +PAIGL T+  K G     ++T   A+ AGYR  D A +Y N+  +  A 
Sbjct: 3   QSLKLNSGYSIPAIGLGTWQSKPGEVAAAIKT---AVAAGYRHIDCAHVYQNQKEVGEAL 59

Query: 414 KKLLPKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKL 593
           K++L + K+KR ++FI SK+    +   A         LS+L L Y+DL L+H P  Y  
Sbjct: 60  KEILDEGKVKREELFITSKVWN-TFHSEAKAHENIDIILSDLQLSYVDLMLIHWPQGYAE 118

Query: 594 D---FENRNSSRIR------KQTWATLVDLYHDHKIRALGVSNY 698
               F    + ++R       +TW          K R++G+SN+
Sbjct: 119 GAELFPAGENGKMRYSDVDYLETWKAFEAAQKAGKCRSIGLSNF 162


>UniRef50_Q2BBN7 Cluster: YvgN; n=1; Bacillus sp. NRRL B-14911|Rep:
           YvgN - Bacillus sp. NRRL B-14911
          Length = 268

 Score = 68.9 bits (161), Expect = 3e-10
 Identities = 49/163 (30%), Positives = 74/163 (45%), Gaps = 10/163 (6%)
 Frame = +3

Query: 240 QQFTLNNGVEMPAIGLDTFKMGH--------FYTVLQTVDDALKAGYRMFDTAALYGNEV 395
           +  TLNNG+EMP +G  T   G             +  +  A++ GYR  D A +Y NE 
Sbjct: 2   EYITLNNGLEMPIVGTGTNTYGKENNDYNGDLTNEIPELASAIELGYRSIDAAIMYRNEE 61

Query: 396 YLNFAFKKLLPKYKLKRGDIFIISKLLPCN--YGGGAVTERAFHNTLSNLGLDYIDLYLV 569
            +      +L + K+ R + FI +K+            T  A  N+L N   DY+DL L+
Sbjct: 62  LVG----SVLAESKVPREEFFITTKIPASEEYISSKEATRAAIDNSLKNFQTDYLDLLLI 117

Query: 570 HNPGIYKLDFENRNSSRIRKQTWATLVDLYHDHKIRALGVSNY 698
           H P   K+  +N         TW    + Y   K++A+GVSN+
Sbjct: 118 HFPIEDKVQLKN---------TWEVFEEYYEAGKLKAIGVSNF 151


>UniRef50_Q75E75 Cluster: ABL209Cp; n=1; Eremothecium gossypii|Rep:
           ABL209Cp - Ashbya gossypii (Yeast) (Eremothecium
           gossypii)
          Length = 310

 Score = 68.9 bits (161), Expect = 3e-10
 Identities = 50/152 (32%), Positives = 81/152 (53%), Gaps = 3/152 (1%)
 Frame = +3

Query: 252 LNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPK 431
           L++G ++P++GL  +++    TV   V +AL+ GYR+FD+A  Y NE  +       L  
Sbjct: 15  LSDGTQIPSVGLGVYQVSE-QTVQDLVYEALEVGYRLFDSAQAYHNEDGVARGIAAWLKH 73

Query: 432 YK-LKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLG-LDYIDLYLVHNPGIYKLDFEN 605
               +R D++  +K+   N+G  A T+++   +L   G L YIDL LVH P         
Sbjct: 74  APGRRREDVYFTTKINTQNHGYEA-TKKSLEKSLHAAGPLGYIDLVLVHAP--------- 123

Query: 606 RNSSRIRK-QTWATLVDLYHDHKIRALGVSNY 698
             S R R+  TW  L +   + ++R++GVSNY
Sbjct: 124 -MSDRTRRLGTWQALEEAVVEGQVRSIGVSNY 154


>UniRef50_A7EW94 Cluster: Putative uncharacterized protein; n=1;
           Sclerotinia sclerotiorum 1980|Rep: Putative
           uncharacterized protein - Sclerotinia sclerotiorum 1980
          Length = 326

 Score = 68.5 bits (160), Expect = 4e-10
 Identities = 53/158 (33%), Positives = 75/158 (47%)
 Frame = +3

Query: 225 KYILPQQFTLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLN 404
           K+ +  +  +N+G E+P +G   ++          V  A  AGYR  D+AA Y NE    
Sbjct: 39  KFNINSKLRMNSGYEIPILGYGVYQTPASQCE-DLVAKAFDAGYRHVDSAAAYRNEGPCA 97

Query: 405 FAFKKLLPKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGI 584
            A ++      + R DIF  SK+ P +      T+     TL   GL YIDL L+H P  
Sbjct: 98  AAIRRS----SIPREDIFFTSKIPPRSLSYEN-TKAQVAKTLMETGLGYIDLMLIHAP-- 150

Query: 585 YKLDFENRNSSRIRKQTWATLVDLYHDHKIRALGVSNY 698
               +  R +   RK  W  LV+   + KIR+LGVSNY
Sbjct: 151 ----YGGRAA---RKGAWKALVEAQEEGKIRSLGVSNY 181


>UniRef50_P06632 Cluster: 2,5-diketo-D-gluconic acid reductase A;
           n=8; Actinomycetales|Rep: 2,5-diketo-D-gluconic acid
           reductase A - Corynebacterium sp. (strain ATCC 31090)
          Length = 278

 Score = 68.5 bits (160), Expect = 4e-10
 Identities = 49/151 (32%), Positives = 77/151 (50%)
 Frame = +3

Query: 252 LNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPK 431
           LN+G  +P +G   FK+    T  + V++AL+ GYR  DTAA+YGNE  +  A    +  
Sbjct: 8   LNDGNSIPQLGYGVFKVPPADTQ-RAVEEALEVGYRHIDTAAIYGNEEGVGAA----IAA 62

Query: 432 YKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLDFENRN 611
             + R D+FI +KL    + G      A   +L+ L LD +DLYLVH P     ++ +  
Sbjct: 63  SGIARDDLFITTKLWNDRHDGDE-PAAAIAESLAKLALDQVDLYLVHWPTPAADNYVH-- 119

Query: 612 SSRIRKQTWATLVDLYHDHKIRALGVSNYFI 704
                   W  +++L      R++GVSN+ +
Sbjct: 120 -------AWEKMIELRAAGLTRSIGVSNHLV 143


>UniRef50_UPI0000D56CE5 Cluster: PREDICTED: similar to CG6084-PA,
           isoform A; n=1; Tribolium castaneum|Rep: PREDICTED:
           similar to CG6084-PA, isoform A - Tribolium castaneum
          Length = 493

 Score = 68.1 bits (159), Expect = 6e-10
 Identities = 46/149 (30%), Positives = 79/149 (53%)
 Frame = +3

Query: 252 LNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPK 431
           LNNG+E+P  GL   +   F+ V + V   + + YR+ D  +++ NE     A ++L+  
Sbjct: 13  LNNGIEIPVFGLAAPQ--DFFEV-ENVQLVVSSNYRLMD-CSIFENEKRFGVALQQLIEG 68

Query: 432 YKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLDFENRN 611
            K++R D+F++SK   C      + + A  +TL  L + Y+DLYL+  P   K      +
Sbjct: 69  GKIRRKDLFLMSKF--CCTNTTNLVKAALLDTLKKLQVAYLDLYLIERPPACK------D 120

Query: 612 SSRIRKQTWATLVDLYHDHKIRALGVSNY 698
            + I  +TW  +  LY +   RA+G+SN+
Sbjct: 121 HNLI--ETWEAMEGLYSEKLTRAIGLSNF 147


>UniRef50_Q0VGY1 Cluster: 3-alpha-hydroxysteroid dehydrogenase;
           n=13; Tetrapoda|Rep: 3-alpha-hydroxysteroid
           dehydrogenase - Xenopus tropicalis (Western clawed frog)
           (Silurana tropicalis)
          Length = 324

 Score = 68.1 bits (159), Expect = 6e-10
 Identities = 51/160 (31%), Positives = 76/160 (47%), Gaps = 11/160 (6%)
 Frame = +3

Query: 252 LNNGVEMPAIGLDTFKMGHFYTVL--QTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLL 425
           LN+G +MP IG  T+    F   L  +    A+  GYR  D A LYGNE  +  A +  +
Sbjct: 11  LNDGHKMPVIGFGTYAPPKFPKSLAEEGTKVAIDVGYRHIDCAFLYGNEEEVGRAIRAKI 70

Query: 426 PKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYK----L 593
               +KR D+F   KL   ++    V   A   +L +L LDY+DL+++H P  +K    L
Sbjct: 71  ADGTVKREDVFYTGKLWSTSHTPERV-RPALEKSLKDLQLDYMDLFIIHMPMEFKPGDDL 129

Query: 594 DFENRNSSRI-----RKQTWATLVDLYHDHKIRALGVSNY 698
              + N   I      + TW  L        +R++GVSN+
Sbjct: 130 FPADENGKFIYHNTDLRDTWKALEKCKDAGLVRSIGVSNF 169


>UniRef50_Q9FJK0 Cluster: Aldose reductase-like protein; n=3; core
           eudicotyledons|Rep: Aldose reductase-like protein -
           Arabidopsis thaliana (Mouse-ear cress)
          Length = 316

 Score = 68.1 bits (159), Expect = 6e-10
 Identities = 48/157 (30%), Positives = 78/157 (49%), Gaps = 8/157 (5%)
 Frame = +3

Query: 252 LNNGVEMPAIGLDTF-KMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLP 428
           L  G  +P +G+ T+       + +  V  A+K GYR FDTA +YG+E  L  A  + + 
Sbjct: 8   LRCGETIPLLGMGTYCPQKDRESTISAVHQAIKIGYRHFDTAKIYGSEEALGTALGQAIS 67

Query: 429 KYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVH-----NPGIYK- 590
              ++R D+F+ SKL   ++        A   TL  +GLDY+D YLVH      PG+ + 
Sbjct: 68  YGTVQRDDLFVTSKLWSSDHHDPI---SALIQTLKTMGLDYLDNYLVHWPIKLKPGVSEP 124

Query: 591 LDFENRNSSRIR-KQTWATLVDLYHDHKIRALGVSNY 698
           +  E+     +  ++TW  +         R++GVSN+
Sbjct: 125 IPKEDEFEKDLGIEETWQGMERCLEMGLCRSIGVSNF 161


>UniRef50_Q8G7K9 Cluster: Dehydrogenase or reductase protein; n=4;
           Bifidobacterium|Rep: Dehydrogenase or reductase protein
           - Bifidobacterium longum
          Length = 289

 Score = 67.7 bits (158), Expect = 8e-10
 Identities = 48/149 (32%), Positives = 73/149 (48%)
 Frame = +3

Query: 252 LNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPK 431
           L +G  +P +GL   ++     V+  V+ AL+AGYR  D AA Y NE  +  A       
Sbjct: 16  LKDGHSIPQVGLGVLRIDD-EGVVPVVESALEAGYRHIDGAAGYNNEAGVGRALAASGYN 74

Query: 432 YKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLDFENRN 611
              KR  +++ +KL     G  +   +AF N+L  L LDY+D+Y++H P      F+ R+
Sbjct: 75  KGAKRETLWVTTKLRDSQQGYDSAL-KAFDNSLKLLQLDYVDMYMIHWP----TPFDWRS 129

Query: 612 SSRIRKQTWATLVDLYHDHKIRALGVSNY 698
           +      TW   V L  +   R LGV N+
Sbjct: 130 T-----DTWKAFVKLRDEGMARTLGVCNF 153


>UniRef50_Q7ZWA4 Cluster: Zgc:56622; n=6; cellular organisms|Rep:
           Zgc:56622 - Danio rerio (Zebrafish) (Brachydanio rerio)
          Length = 289

 Score = 67.3 bits (157), Expect = 1e-09
 Identities = 44/129 (34%), Positives = 70/129 (54%), Gaps = 9/129 (6%)
 Frame = +3

Query: 339 ALKAGYRMFDTAALYGNEVYLNFAFKKLLPKYKLKRGDIFIISKLLPCNYGGGAVTERAF 518
           A+ AGYR  DTA  Y NEV +  A +  + +  ++R D+FI+SKL   ++    +    F
Sbjct: 9   AIAAGYRHIDTAFCYRNEVDVGMAIQNKIQQGIIRRQDMFIVSKLWGTHHAPEDIPV-CF 67

Query: 519 HNTLSNLGLDYIDLYLVHNP-GIYKLD---FENRNSSRIRK-----QTWATLVDLYHDHK 671
           + +LS+L LDY+D YLVH P G+ K+    F  R+   +         W  +  L    K
Sbjct: 68  NKSLSDLQLDYLDQYLVHFPVGLKKVGDELFPERDGKILTTDIDYVDVWRGMEALKATGK 127

Query: 672 IRALGVSNY 698
           ++++GVSN+
Sbjct: 128 VKSIGVSNF 136


>UniRef50_Q7QK25 Cluster: ENSANGP00000019775; n=2; Anopheles gambiae
           str. PEST|Rep: ENSANGP00000019775 - Anopheles gambiae
           str. PEST
          Length = 319

 Score = 67.3 bits (157), Expect = 1e-09
 Identities = 37/108 (34%), Positives = 60/108 (55%)
 Frame = +3

Query: 255 NNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPKY 434
           +NG E+P +G  T+ +      ++ V  A+  GYR  DTA LY NEV +  A +  + + 
Sbjct: 11  SNGYEIPVLGYGTY-LAQKGQCVELVKKAIDLGYRHIDTAFLYENEVEIGQAIRDKIAEG 69

Query: 435 KLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNP 578
            ++R D+F+ +KL    +    V E AF  +   L + YIDL+L+H+P
Sbjct: 70  VIRREDVFVTTKLWNTFHDPQHV-EEAFRRSFDMLDIGYIDLFLMHSP 116


>UniRef50_Q4JX70 Cluster: Putative oxidoreductase; n=1;
           Corynebacterium jeikeium K411|Rep: Putative
           oxidoreductase - Corynebacterium jeikeium (strain K411)
          Length = 285

 Score = 66.9 bits (156), Expect = 1e-09
 Identities = 38/109 (34%), Positives = 61/109 (55%)
 Frame = +3

Query: 252 LNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPK 431
           +N+G   P +GL  +++    T   +V  A++ GYR  DTAA+YGNE  +  A    +  
Sbjct: 13  MNDGKTTPQLGLGVWQLSDEDTYT-SVRAAIETGYRHIDTAAIYGNEEAVGRAVADAVKA 71

Query: 432 YKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNP 578
             ++R ++FI +KL   +   G   + AF  +   LG+DY+DLYL+H P
Sbjct: 72  GDVQREELFITTKLWNADQACG---KEAFAESQKKLGMDYVDLYLLHWP 117


>UniRef50_Q01HB5 Cluster: OSIGBa0136O08-OSIGBa0153H12.9 protein;
           n=4; Oryza sativa|Rep: OSIGBa0136O08-OSIGBa0153H12.9
           protein - Oryza sativa (Rice)
          Length = 337

 Score = 66.9 bits (156), Expect = 1e-09
 Identities = 40/111 (36%), Positives = 60/111 (54%), Gaps = 1/111 (0%)
 Frame = +3

Query: 249 TLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLP 428
           TLN+G  MP +G  T        +  T+  A++ GYR  DTAA+YG E  +  A  + + 
Sbjct: 24  TLNSGHAMPVLGFGTGSSTPPADLAATIAHAVRLGYRHLDTAAVYGTEGAVGAAVAEAVR 83

Query: 429 KYKL-KRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNP 578
              +  RG++F+ +KL   +     V   A   +LS LGLDY+DL+L+H P
Sbjct: 84  CGAVASRGELFVTTKLSMADAHPPRVVA-ALRESLSRLGLDYVDLFLIHWP 133


>UniRef50_A7SGW6 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 264

 Score = 66.9 bits (156), Expect = 1e-09
 Identities = 53/151 (35%), Positives = 78/151 (51%), Gaps = 1/151 (0%)
 Frame = +3

Query: 249 TLNNGVEMPAIGLDTFKMGHFYTVLQTVD-DALKAGYRMFDTAALYGNEVYLNFAFKKLL 425
           TLN+G +MP  GL  F++    T  + V   ALK GYRM DTA +Y NE  +  A +   
Sbjct: 14  TLNDGRKMPLFGLGVFRLE---TGCEDVCLFALKNGYRMLDTADIYQNEKEVGSAVR--- 67

Query: 426 PKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLDFEN 605
            K  LKR DI++ +KL P   G     + A   ++  L + Y+DL+L+H P         
Sbjct: 68  -KSGLKREDIYVTTKLKPSEEGHSNALKYA-KESIKKLDIGYVDLFLIHTP--------- 116

Query: 606 RNSSRIRKQTWATLVDLYHDHKIRALGVSNY 698
           R  + I    +  L+ L  +  IR++GVSN+
Sbjct: 117 RPGNII--AAYDALLTLKEEGLIRSVGVSNF 145


>UniRef50_Q7G765 Cluster: Probable NAD(P)H-dependent oxidoreductase
           2; n=6; Magnoliophyta|Rep: Probable NAD(P)H-dependent
           oxidoreductase 2 - Oryza sativa subsp. japonica (Rice)
          Length = 322

 Score = 66.9 bits (156), Expect = 1e-09
 Identities = 51/153 (33%), Positives = 73/153 (47%), Gaps = 10/153 (6%)
 Frame = +3

Query: 270 MPAIGLDT--FKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPKYKL- 440
           MP IG+ T  F           +  A++ GYR FDTA LY  E  ++ A  + + +  + 
Sbjct: 18  MPRIGMGTAAFPFTSSEETTAALLRAIELGYRHFDTARLYATEGCVSEAVAEAVRRGLVA 77

Query: 441 KRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVH-----NPGIYKLDF-- 599
            R D+F+ SKL   +   G V   A   TL NLG+DY+DL LVH      PG Y   F  
Sbjct: 78  SRADVFVTSKLWCSDLHAGRVVPAA-RETLRNLGMDYVDLLLVHWPATVAPGSYDFPFPK 136

Query: 600 ENRNSSRIRKQTWATLVDLYHDHKIRALGVSNY 698
           E    +   +  W  + + +     RA+GVSN+
Sbjct: 137 EEMAPAFDMEGVWRGMEECHRLGLARAIGVSNF 169


>UniRef50_Q5FK99 Cluster: Oxidoreductase aldo-keto reductase family;
           n=5; Lactobacillus|Rep: Oxidoreductase aldo-keto
           reductase family - Lactobacillus acidophilus
          Length = 289

 Score = 66.5 bits (155), Expect = 2e-09
 Identities = 46/150 (30%), Positives = 72/150 (48%)
 Frame = +3

Query: 252 LNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPK 431
           LN+G E+P +G   F++ +    ++ V+ A+  GYR+ DTA  Y N+  +  A K     
Sbjct: 9   LNDGNEIPQLGFGVFQISNHDEAVKAVESAISNGYRLIDTAEAYNNQTAVGEAIK----N 64

Query: 432 YKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLDFENRN 611
             + R DIF+ +KL   N+     + +A    L  LG DYID+ L+H    Y  D     
Sbjct: 65  SDVNRDDIFLTTKLWVSNFTYEKAS-KAIDEDLKELGTDYIDMMLLHQ--AYG-DVAG-- 118

Query: 612 SSRIRKQTWATLVDLYHDHKIRALGVSNYF 701
                   W  L D     K +++GVSN++
Sbjct: 119 -------AWRALEDAQKAGKTKSIGVSNFW 141


>UniRef50_Q9P6D3 Cluster: Related to aldo-keto reductase YPR1; n=10;
           Pezizomycotina|Rep: Related to aldo-keto reductase YPR1
           - Neurospora crassa
          Length = 322

 Score = 66.5 bits (155), Expect = 2e-09
 Identities = 43/122 (35%), Positives = 67/122 (54%)
 Frame = +3

Query: 339 ALKAGYRMFDTAALYGNEVYLNFAFKKLLPKYKLKRGDIFIISKLLPCNYGGGAVTERAF 518
           AL AGY   D A +YGNEV L  A    + + KL R  ++I +K +     G  VT+ +F
Sbjct: 67  ALNAGYAHLDGAEVYGNEVELGRA----IAQSKLPRSSLYITTKTIV--RAGDTVTQ-SF 119

Query: 519 HNTLSNLGLDYIDLYLVHNPGIYKLDFENRNSSRIRKQTWATLVDLYHDHKIRALGVSNY 698
           + +L  LGLDY+DLYL+H+P      F  +N  ++ +  W  +  +      +++GVSN+
Sbjct: 120 NRSLEKLGLDYVDLYLLHSP------FFAKNPEQL-QAAWREMEKIKDSGMAKSIGVSNF 172

Query: 699 FI 704
            I
Sbjct: 173 LI 174


>UniRef50_Q0CLQ2 Cluster: Putative uncharacterized protein; n=1;
           Aspergillus terreus NIH2624|Rep: Putative
           uncharacterized protein - Aspergillus terreus (strain
           NIH 2624)
          Length = 301

 Score = 66.5 bits (155), Expect = 2e-09
 Identities = 44/110 (40%), Positives = 62/110 (56%)
 Frame = +3

Query: 240 QQFTLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKK 419
           + F L++G +MPA+GL T+ +   + V   V+ AL+ GYR  D AA Y NE  +   +KK
Sbjct: 5   RSFKLSSGYDMPAVGLGTW-LSKPHEVENAVETALRLGYRHIDAAACYLNENEVGNGWKK 63

Query: 420 LLPKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLV 569
                 + R  IFI SKL   ++    V E A + TL +L  DY+DLYLV
Sbjct: 64  S----GVPRDQIFITSKLWNTHHHPDHV-EEAVNKTLKDLQTDYLDLYLV 108


>UniRef50_Q7N0E4 Cluster: 2,5-diketo-D-gluconic acid reductase A;
           n=2; Bacteria|Rep: 2,5-diketo-D-gluconic acid reductase
           A - Photorhabdus luminescens subsp. laumondii
          Length = 292

 Score = 66.1 bits (154), Expect = 2e-09
 Identities = 48/149 (32%), Positives = 73/149 (48%)
 Frame = +3

Query: 252 LNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPK 431
           L +G  MP +GL ++       + +T+  AL  GYR  DTAA+Y NE  +  A    L +
Sbjct: 9   LADGNHMPQLGLGSWASDD-QQIAETIHAALDIGYRAIDTAAIYNNEKGVGNA----LQE 63

Query: 432 YKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLDFENRN 611
             + R DIF+ +KL    +        A   +L  L LDY+DLYL+H P   +  +    
Sbjct: 64  TDIPREDIFVTTKLWNDRH---LDARAALTESLEKLQLDYVDLYLIHWPAPPQDQYVG-- 118

Query: 612 SSRIRKQTWATLVDLYHDHKIRALGVSNY 698
                   W  L++L  +  IR++GVSN+
Sbjct: 119 -------AWQQLIELQKEGLIRSIGVSNF 140


>UniRef50_Q7PCV3 Cluster: ENSANGP00000031808; n=9;
           Endopterygota|Rep: ENSANGP00000031808 - Anopheles
           gambiae str. PEST
          Length = 316

 Score = 66.1 bits (154), Expect = 2e-09
 Identities = 42/111 (37%), Positives = 57/111 (51%)
 Frame = +3

Query: 258 NGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPKYK 437
           NG  +P  GL T+       V Q V DA+  GYR  D A +Y NE  +       + +  
Sbjct: 13  NGNSIPMFGLGTWNSPPGQ-VAQAVKDAIDVGYRHIDCAHVYQNEHEVGEGIAAKIAEGV 71

Query: 438 LKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYK 590
           +KR D+F+ SKL    +    + E A   TL NL LDY+DLYL+H P  Y+
Sbjct: 72  VKREDLFVTSKLWN-TFHRPDLVEGACKTTLQNLKLDYLDLYLIHWPVGYQ 121


>UniRef50_Q68ST9 Cluster: Reductase AKOR2; n=2; Pleurotus
           djamor|Rep: Reductase AKOR2 - Pleurotus djamor
          Length = 306

 Score = 66.1 bits (154), Expect = 2e-09
 Identities = 58/165 (35%), Positives = 79/165 (47%), Gaps = 14/165 (8%)
 Frame = +3

Query: 252 LNNGVEMPAIGLDTFKMGHFYTVLQTVD---DALKAGYRMFDTAALYGNEVYLNFAFKKL 422
           LN G  MPA+ L  +         Q  +    ALK+GYR  DTA +Y  E  +  A ++ 
Sbjct: 9   LNTGARMPALALGGWAGLTEEERTQAKEWFLTALKSGYRHIDTAQIYYTEKSVGNAIRES 68

Query: 423 LPKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPG--IY--K 590
                + R ++FI +KL P N+    V E +F  +L NLG +YIDLYLVH P    Y   
Sbjct: 69  ----GIPREELFITTKL-PWNHHS-RVAE-SFQKSLENLGTEYIDLYLVHFPQRVFYDET 121

Query: 591 LDFENRNSSRIR-------KQTWATLVDLYHDHKIRALGVSNYFI 704
            DF       I+          WA +  L    K++A+GVSNY I
Sbjct: 122 TDFPRNPDGSIKVVNSPTLNDVWADVETLLDTGKVKAIGVSNYSI 166


>UniRef50_Q96JD6-2 Cluster: Isoform 2 of Q96JD6 ; n=4;
           Catarrhini|Rep: Isoform 2 of Q96JD6 - Homo sapiens
           (Human)
          Length = 263

 Score = 65.7 bits (153), Expect = 3e-09
 Identities = 38/108 (35%), Positives = 61/108 (56%)
 Frame = +3

Query: 267 EMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPKYKLKR 446
           ++PA+GL ++K      V + V +A+ AGYR FD A  Y NE  +    +  + +  ++R
Sbjct: 3   DIPAVGLSSWKASPG-KVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEGAVRR 61

Query: 447 GDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYK 590
            D+FI +KL  C     ++ E A   +L  L L+Y+DLYL+H P  +K
Sbjct: 62  EDLFIATKLW-CTCHKKSLVETACRKSLKALKLNYLDLYLIHWPMGFK 108


>UniRef50_Q83N50 Cluster: 2,5-diketo-D-gluconic acid reductase; n=2;
           Tropheryma whipplei|Rep: 2,5-diketo-D-gluconic acid
           reductase - Tropheryma whipplei (strain Twist)
           (Whipple's bacillus)
          Length = 283

 Score = 65.7 bits (153), Expect = 3e-09
 Identities = 46/149 (30%), Positives = 72/149 (48%)
 Frame = +3

Query: 252 LNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPK 431
           L +GV +P  GL T+++         V  A++ GYR  DTA+LY NE  +  A    +  
Sbjct: 14  LGDGVSIPQFGLGTYELPP-NEASSVVQSAIELGYRHIDTASLYANEREVGRA----IAS 68

Query: 432 YKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLDFENRN 611
             +KR + F+ +KL   +         AF  +L  L LDY+DLYL+H P           
Sbjct: 69  SGIKREEFFVTTKLWNSDQ---PKPREAFERSLDLLSLDYVDLYLIHWP---------CP 116

Query: 612 SSRIRKQTWATLVDLYHDHKIRALGVSNY 698
            S +    W  L++L    + +++GVSN+
Sbjct: 117 PSELYINVWEVLLELKESGRAKSVGVSNF 145


>UniRef50_Q572D2 Cluster: Aldo-keto reductase, putative; n=1;
           Phytophthora infestans|Rep: Aldo-keto reductase,
           putative - Phytophthora infestans (Potato late blight
           fungus)
          Length = 255

 Score = 65.7 bits (153), Expect = 3e-09
 Identities = 47/149 (31%), Positives = 69/149 (46%)
 Frame = +3

Query: 252 LNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPK 431
           L +G  +P IGL  ++          +  +LK GYR  DTA +YGNE  +  A +     
Sbjct: 10  LPSGARIPMIGLGVYQSEPGPETYNAILTSLKLGYRHIDTAEIYGNEEDVGRAVR----D 65

Query: 432 YKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLDFENRN 611
             + R +IF+ +KL   N+G       A   +   LG+ YI LYL+H PG          
Sbjct: 66  SGIPREEIFVTTKLFTTNWGYSKAL-AAGKASNDRLGIVYIYLYLLHAPG---------- 114

Query: 612 SSRIRKQTWATLVDLYHDHKIRALGVSNY 698
             + R  TW  + DL     +R +GVSN+
Sbjct: 115 PPKERADTWRAVEDLREQETLRDIGVSNF 143


>UniRef50_Q68A33 Cluster: Aldo-keto reductase 1a; n=1; Ciona
           intestinalis|Rep: Aldo-keto reductase 1a - Ciona
           intestinalis (Transparent sea squirt)
          Length = 584

 Score = 65.7 bits (153), Expect = 3e-09
 Identities = 50/162 (30%), Positives = 76/162 (46%), Gaps = 11/162 (6%)
 Frame = +3

Query: 252 LNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALY-GNEVYLNFAFK---- 416
           LN+G  MP IGL T ++  F    +TV  ALK GYRM DTA +Y G +   NF       
Sbjct: 262 LNSGYMMPPIGLGTARL--FSKTYETVKTALKLGYRMLDTAQIYTGEDKINNFKVSSEEE 319

Query: 417 --KLLPKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVH----NP 578
             + +    + R ++FI++KL P +        +    +L  L  DYIDL L+H    + 
Sbjct: 320 IGRAIADSDVPRSELFIVTKLAPESMEKENAIAKV-EESLKKLRTDYIDLLLIHDFYMST 378

Query: 579 GIYKLDFENRNSSRIRKQTWATLVDLYHDHKIRALGVSNYFI 704
                D +           W T+ ++     +R++GVSN +I
Sbjct: 379 ACGPDDTDLPECKNNPFLAWKTMEEMQAKGLVRSIGVSNIYI 420


>UniRef50_Q96JD6 Cluster: Aldo-keto reductase family 1 member C-like
           protein 2; n=37; Euteleostomi|Rep: Aldo-keto reductase
           family 1 member C-like protein 2 - Homo sapiens (Human)
          Length = 320

 Score = 65.7 bits (153), Expect = 3e-09
 Identities = 38/108 (35%), Positives = 61/108 (56%)
 Frame = +3

Query: 267 EMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPKYKLKR 446
           ++PA+GL ++K      V + V +A+ AGYR FD A  Y NE  +    +  + +  ++R
Sbjct: 3   DIPAVGLSSWKASPG-KVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEGAVRR 61

Query: 447 GDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYK 590
            D+FI +KL  C     ++ E A   +L  L L+Y+DLYL+H P  +K
Sbjct: 62  EDLFIATKLW-CTCHKKSLVETACRKSLKALKLNYLDLYLIHWPMGFK 108


>UniRef50_A5VK30 Cluster: 2,5-didehydrogluconate reductase; n=2;
           Lactobacillus reuteri|Rep: 2,5-didehydrogluconate
           reductase - Lactobacillus reuteri F275
          Length = 300

 Score = 65.3 bits (152), Expect = 4e-09
 Identities = 46/155 (29%), Positives = 72/155 (46%)
 Frame = +3

Query: 234 LPQQFTLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAF 413
           L  +  LNNG  +P +GL  +K     T  Q V +A+   Y + DTA  YGNE  +    
Sbjct: 9   LQPKIKLNNGHLIPQLGLGVWKASLAETQ-QMVKEAIMNDYVLIDTAKQYGNEAAVGQGI 67

Query: 414 KKLLPKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKL 593
           +        KR  IF+ +K+   + G      +A +  L  L  +Y+DL L+H P   K 
Sbjct: 68  QDGFKATGRKRDSIFLTTKIFNGDQGDYDKLRQAVNEQLKKLQTNYVDLLLLHWPVNDKY 127

Query: 594 DFENRNSSRIRKQTWATLVDLYHDHKIRALGVSNY 698
           +           ++W  L D+Y D + +A+GV N+
Sbjct: 128 N-----------ESWRALEDIYKDGQAKAIGVCNF 151


>UniRef50_Q7XY49 Cluster: Mannose 6-phosphate reductase; n=1;
           Griffithsia japonica|Rep: Mannose 6-phosphate reductase
           - Griffithsia japonica (Red alga)
          Length = 174

 Score = 65.3 bits (152), Expect = 4e-09
 Identities = 41/112 (36%), Positives = 60/112 (53%)
 Frame = +3

Query: 249 TLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLP 428
           TL +G +MP  G  T+K     T  Q V  AL+AGYR  D AA+Y NE  +  A  K + 
Sbjct: 7   TLQSGAKMPLNGFGTWKASVEETE-QAVTAALRAGYRHIDCAAVYWNEAAVGTAISKAIS 65

Query: 429 KYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGI 584
              +KR D+FI SK+    +    V + +   +L +  +DY DL+LV + G+
Sbjct: 66  GGVVKREDLFITSKVWNTCHATDKVVD-SCRQSLKDHQVDYFDLFLVRDIGV 116


>UniRef50_Q7QVQ9 Cluster: GLP_302_44328_45269; n=1; Giardia lamblia
           ATCC 50803|Rep: GLP_302_44328_45269 - Giardia lamblia
           ATCC 50803
          Length = 313

 Score = 65.3 bits (152), Expect = 4e-09
 Identities = 50/157 (31%), Positives = 77/157 (49%), Gaps = 13/157 (8%)
 Frame = +3

Query: 273 PAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPKYK--LKR 446
           P +G  T++      V   V+ AL  GYR  D A +Y NE  +  AF K+       +KR
Sbjct: 5   PRLGFGTWQAPP-EAVQTAVETALMTGYRHIDCAYVYQNEEAIGRAFGKIFKDASSGIKR 63

Query: 447 GDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNP---------GIYKLDF 599
            D++I SKL   N+    V E+    T+S+L +DY+DL+LVH P          ++  D 
Sbjct: 64  EDVWITSKLWNYNHRPELVREQC-KKTMSDLQVDYLDLFLVHWPLAFVRNDVGDLFPKDA 122

Query: 600 ENRNS-SRI-RKQTWATLVDLYHDHKIRALGVSNYFI 704
           E R    ++    TW  +  L  +  ++ +GVSNY +
Sbjct: 123 EGRAMLEKVPLADTWRAMEQLVEEGLVKHIGVSNYTV 159


>UniRef50_Q8J0K1 Cluster: 4-dihydromethyltrisporate dehydrogenase;
           n=2; Parasitella parasitica|Rep:
           4-dihydromethyltrisporate dehydrogenase - Parasitella
           parasitica
          Length = 321

 Score = 65.3 bits (152), Expect = 4e-09
 Identities = 34/84 (40%), Positives = 49/84 (58%)
 Frame = +3

Query: 327 TVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPKYKLKRGDIFIISKLLPCNYGGGAVT 506
           T+  A+K GYR+FD A  YGNEV +     K + +  +KR ++FI++KL    +    V 
Sbjct: 33  TIYQAIKIGYRLFDGACDYGNEVEVGRGINKAIKEGLVKREELFIVTKLWNTFHSKQHV- 91

Query: 507 ERAFHNTLSNLGLDYIDLYLVHNP 578
             AF   L + GL+Y DLYL+H P
Sbjct: 92  RTAFDRQLKDWGLEYFDLYLIHFP 115


>UniRef50_A5DRJ6 Cluster: Putative uncharacterized protein; n=4;
           Pichia guilliermondii|Rep: Putative uncharacterized
           protein - Pichia guilliermondii (Yeast) (Candida
           guilliermondii)
          Length = 287

 Score = 65.3 bits (152), Expect = 4e-09
 Identities = 49/153 (32%), Positives = 74/153 (48%), Gaps = 2/153 (1%)
 Frame = +3

Query: 246 FTLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLL 425
           F L NG  +PA G+  + +    T    V+ AL  GYR+ DTA  Y NE       K  L
Sbjct: 10  FPLLNGSRIPACGVGVYLLPASQTA-GIVEKALDVGYRLIDTAQEYENERETGEGIKAWL 68

Query: 426 PKYK-LKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNL-GLDYIDLYLVHNPGIYKLDF 599
            K K  KR D+   +K+   N G    T R+   +L+ +  L+YIDL L+H+P       
Sbjct: 69  GKDKNNKREDVLYTTKITNLNQGYDR-TWRSLKESLNKVKHLEYIDLVLIHDP------- 120

Query: 600 ENRNSSRIRKQTWATLVDLYHDHKIRALGVSNY 698
              +  + R +TW  L +      ++++GVSN+
Sbjct: 121 --LSDKKTRIETWKALQEAVDSGMVKSIGVSNF 151


>UniRef50_P26690 Cluster: NAD(P)H-dependent 6'-deoxychalcone
           synthase; n=3; Papilionoideae|Rep: NAD(P)H-dependent
           6'-deoxychalcone synthase - Glycine max (Soybean)
          Length = 315

 Score = 65.3 bits (152), Expect = 4e-09
 Identities = 43/133 (32%), Positives = 66/133 (49%), Gaps = 6/133 (4%)
 Frame = +3

Query: 324 QTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPKYKLKRGDIFIISKLLPCNYGGGAV 503
           + + +A+K GYR FDTAA YG+E  L  A K+ +    + R D+F+ SKL         V
Sbjct: 40  EAIIEAVKQGYRHFDTAAAYGSEQALGEALKEAIHLGLVSRQDLFVTSKLWVTENHPHLV 99

Query: 504 TERAFHNTLSNLGLDYIDLYLVH-----NPGIYKLDFENRNSSRIR-KQTWATLVDLYHD 665
              A   +L  L L+Y+DLYL+H      PG +    E  +      K  W ++ +    
Sbjct: 100 LP-ALRKSLKTLQLEYLDLYLIHWPLSSQPGKFSFPIEVEDLLPFDVKGVWESMEECQKL 158

Query: 666 HKIRALGVSNYFI 704
              +A+GVSN+ +
Sbjct: 159 GLTKAIGVSNFSV 171


>UniRef50_Q4WUF7 Cluster: Aldo-keto reductase, putative; n=3;
           Pezizomycotina|Rep: Aldo-keto reductase, putative -
           Aspergillus fumigatus (Sartorya fumigata)
          Length = 283

 Score = 64.9 bits (151), Expect = 5e-09
 Identities = 45/149 (30%), Positives = 75/149 (50%), Gaps = 1/149 (0%)
 Frame = +3

Query: 255 NNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPKY 434
           N+ V++P +G   ++      V  ++  AL+AGYR  DTA  YGNE  +  A +K     
Sbjct: 15  NSDVKIPRLGFGVYRSPTGQCVQSSLR-ALEAGYRHIDTAQFYGNEKEVGEALRKC---- 69

Query: 435 KLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLD-YIDLYLVHNPGIYKLDFENRN 611
            + R D+F+ +K+L       A  ++   +     G D Y+DL+L+H+         + +
Sbjct: 70  GIPRSDVFVTTKILSPAGSPEATYQKLLESVEKIGGRDGYVDLFLIHS---------SSS 120

Query: 612 SSRIRKQTWATLVDLYHDHKIRALGVSNY 698
            S  RK+ W  L  L  + K R++GVSN+
Sbjct: 121 GSAGRKELWQALERLLEEGKTRSIGVSNF 149


>UniRef50_Q5UX52 Cluster: Oxidoreductase aldo/keto reductase family;
           n=1; Haloarcula marismortui|Rep: Oxidoreductase
           aldo/keto reductase family - Haloarcula marismortui
           (Halobacterium marismortui)
          Length = 274

 Score = 64.9 bits (151), Expect = 5e-09
 Identities = 46/146 (31%), Positives = 73/146 (50%)
 Frame = +3

Query: 261 GVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPKYKL 440
           G  +PA+GL T+++    +  +TV+ AL  GYR  DTA  YGNE  +       +    +
Sbjct: 8   GTSVPALGLGTWQLTG-QSCRETVETALGMGYRHIDTAQAYGNERQVGLG----MDAAAV 62

Query: 441 KRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLDFENRNSSR 620
            R D+F+ +KL   N    +V  R+   +L+ LG DY+DL L+H P        N     
Sbjct: 63  DREDVFLTTKLDGSNRDERSV-RRSTRESLNKLGTDYLDLLLIHWP--------NTPWMA 113

Query: 621 IRKQTWATLVDLYHDHKIRALGVSNY 698
              +T   + D+  +  +R +GVSN+
Sbjct: 114 SLSETLGAMNDVVEEGLVRHIGVSNF 139


>UniRef50_A7CUW0 Cluster: 2,5-didehydrogluconate reductase; n=6;
           Bacteria|Rep: 2,5-didehydrogluconate reductase -
           Opitutaceae bacterium TAV2
          Length = 334

 Score = 64.5 bits (150), Expect = 7e-09
 Identities = 48/149 (32%), Positives = 75/149 (50%)
 Frame = +3

Query: 252 LNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPK 431
           L++G  +P +GL  ++M      +  +  A  AGYR  DTA +YGNE  +  A +     
Sbjct: 64  LSDGTSIPQLGLGVWQMPDDGAGVP-IQAAFNAGYRAIDTAPIYGNEEGVGRAIRAS--- 119

Query: 432 YKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLDFENRN 611
             L R +++I +K+     G  + T RA   +L  L L+Y+DLYL+H P + K+D     
Sbjct: 120 -GLPRKELYITTKVWNSAQGYDS-TLRAVRESLGRLQLEYVDLYLIHWP-VPKID----- 171

Query: 612 SSRIRKQTWATLVDLYHDHKIRALGVSNY 698
                  TW  L  +  D   R++GVSN+
Sbjct: 172 ---RYVDTWKALAKIKADGLARSIGVSNF 197


>UniRef50_A5ZYE6 Cluster: Putative uncharacterized protein; n=1;
           Ruminococcus obeum ATCC 29174|Rep: Putative
           uncharacterized protein - Ruminococcus obeum ATCC 29174
          Length = 263

 Score = 64.5 bits (150), Expect = 7e-09
 Identities = 39/103 (37%), Positives = 55/103 (53%)
 Frame = +3

Query: 270 MPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPKYKLKRG 449
           MP +GL  +K          +  A++ GYR+ DTA+ Y NE ++       + K  + R 
Sbjct: 1   MPLLGLGLYKTTDAVEAEDAIAAAVQNGYRLLDTASAYKNEEFVGCG----IAKCGVPRK 56

Query: 450 DIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNP 578
           D+FI +K+       G V E AF  +L  LGLDYIDLYL+H P
Sbjct: 57  DLFITTKIWNNAQRLGDV-EGAFQRSLDRLGLDYIDLYLIHWP 98


>UniRef50_A7RUA2 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 246

 Score = 64.5 bits (150), Expect = 7e-09
 Identities = 48/143 (33%), Positives = 70/143 (48%)
 Frame = +3

Query: 270 MPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPKYKLKRG 449
           +P +G  T  +G     L  V  AL+ GYR+ DTA  Y           K +    + R 
Sbjct: 1   VPVMGFGTATLGE--DTLSVVKTALETGYRLIDTAQGYPLS---EPQVAKAIADSGIPRK 55

Query: 450 DIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLDFENRNSSRIRK 629
           DIFII+KL P  Y G   T ++   +L  L  DYIDL+L+H+             +   K
Sbjct: 56  DIFIITKLHP-RYLGYEPTLKSVEMSLRALSTDYIDLFLIHS------------KTGTWK 102

Query: 630 QTWATLVDLYHDHKIRALGVSNY 698
           ++W  + +L+   KIR+LGVSN+
Sbjct: 103 ESWKAMEELHRQGKIRSLGVSNF 125


>UniRef50_A2G4I3 Cluster: Oxidoreductase, aldo/keto reductase family
           protein; n=2; Eukaryota|Rep: Oxidoreductase, aldo/keto
           reductase family protein - Trichomonas vaginalis G3
          Length = 286

 Score = 64.5 bits (150), Expect = 7e-09
 Identities = 51/153 (33%), Positives = 78/153 (50%), Gaps = 4/153 (2%)
 Frame = +3

Query: 252 LNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKA----GYRMFDTAALYGNEVYLNFAFKK 419
           L+NG ++P IGL  +  G+    L+T   A+K     G  + DTA LYG+ +   F  K 
Sbjct: 10  LSNGNKIPKIGLGCWNFGNPGCPLETEQSAVKTAVNGGMVLLDTAELYGDGLSEEF-LKD 68

Query: 420 LLPKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLDF 599
           L+   + K   +FI+SK+LP N G   +       +L +LG++Y+DLYL+H  G   L  
Sbjct: 69  LIKPIREK---LFIVSKVLPSNAGRKNIFNSC-EKSLQHLGIEYLDLYLLHWRGRVPL-- 122

Query: 600 ENRNSSRIRKQTWATLVDLYHDHKIRALGVSNY 698
                    K+T   + +L    KI+  GVSN+
Sbjct: 123 ---------KETVECMEELVKQGKIKQWGVSNF 146


>UniRef50_Q9HGY0 Cluster: Glycerol dehydrogenase; n=8;
           Saccharomycetaceae|Rep: Glycerol dehydrogenase -
           Zygosaccharomyces rouxii (Candida mogii)
          Length = 310

 Score = 64.5 bits (150), Expect = 7e-09
 Identities = 52/167 (31%), Positives = 80/167 (47%), Gaps = 16/167 (9%)
 Frame = +3

Query: 252 LNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPK 431
           LN G  +P +GL T++        + V +ALKAGYR  D AA+YGNE  +     K +  
Sbjct: 13  LNTGQTIPQVGLGTWRSKE-NEGYKAVIEALKAGYRHIDGAAVYGNEGEVG----KAIQD 67

Query: 432 YKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNP----------- 578
             + R +IF+ +KL  C +      + A   +L  LGLDY+ LYLVH P           
Sbjct: 68  SGVPRNEIFLTTKLW-CTHQRN--PQEALDQSLQRLGLDYVGLYLVHWPVPLRTENIKDG 124

Query: 579 GIYKLDFENRNSSRIRKQ-----TWATLVDLYHDHKIRALGVSNYFI 704
            +++   +   S  +  +     TW  +  L    K +A+GVSN+ +
Sbjct: 125 NLFQFAEKPDGSKDVDLEWNFIKTWELMQKLLESGKTKAIGVSNFSV 171


>UniRef50_Q6CGE9 Cluster: Similar to sp|P47137 Saccharomyces
           cerevisiae Probable oxidoreductase YJR096W; n=2;
           Yarrowia lipolytica|Rep: Similar to sp|P47137
           Saccharomyces cerevisiae Probable oxidoreductase YJR096W
           - Yarrowia lipolytica (Candida lipolytica)
          Length = 287

 Score = 64.5 bits (150), Expect = 7e-09
 Identities = 47/150 (31%), Positives = 69/150 (46%), Gaps = 4/150 (2%)
 Frame = +3

Query: 261 GVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPKY-K 437
           G  +P IGL  +      +  ++V +AL  GYR+FDTA  Y NE        + L     
Sbjct: 15  GTVIPVIGLGVYSSN---STTKSVTEALNLGYRLFDTANEYQNETDTAKGISEWLKSNPN 71

Query: 438 LKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNL---GLDYIDLYLVHNPGIYKLDFENR 608
           +KR D++  +K+     GG   T+      L+     GLDYID+ ++H P      +   
Sbjct: 72  VKREDVWYCTKIDDAR-GGYEGTKSRVEEALTKAKVGGLDYIDMLIIHAP------YTAP 124

Query: 609 NSSRIRKQTWATLVDLYHDHKIRALGVSNY 698
             +  R + W  L +   D KIR L VSNY
Sbjct: 125 PHTETRMKVWKALSEFVDDGKIRTLAVSNY 154


>UniRef50_Q4DJ59 Cluster: Aldo/keto reductase, putative; n=2;
           Trypanosoma|Rep: Aldo/keto reductase, putative -
           Trypanosoma cruzi
          Length = 322

 Score = 64.1 bits (149), Expect = 9e-09
 Identities = 41/149 (27%), Positives = 76/149 (51%), Gaps = 1/149 (0%)
 Frame = +3

Query: 255 NNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPKY 434
           + G+ +P +G+ T+++    + +  +  AL+ G+R+ DTAA Y NE ++  A ++     
Sbjct: 21  SGGMRIPHMGVGTYELYGDESRIAVLA-ALRLGFRLVDTAAGYHNEEHVGAAIEES---- 75

Query: 435 KLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLDFENRNS 614
            ++R ++F++ K+ P       + E+    ++  L + Y D  L+H PG   L  E    
Sbjct: 76  GVQREELFVVVKIAPKAMASEELVEKGIRESVRKLRIAYADCVLIHWPGCGGLKPEEAEG 135

Query: 615 SR-IRKQTWATLVDLYHDHKIRALGVSNY 698
            R  R + W  +  L  +  IR LGVSN+
Sbjct: 136 HRAARHRCWKVMQALKKEGIIRHLGVSNF 164


>UniRef50_Q76L37 Cluster: Conjugated polyketone reductase C1; n=3;
           Saccharomycetales|Rep: Conjugated polyketone reductase
           C1 - Candida parapsilosis (Yeast)
          Length = 304

 Score = 64.1 bits (149), Expect = 9e-09
 Identities = 52/168 (30%), Positives = 82/168 (48%), Gaps = 13/168 (7%)
 Frame = +3

Query: 240 QQFTLNNGVEMPAIGLDT----FKMGHF---YTVLQTVDDALKAGYRMFDTAALYGNEVY 398
           ++F L+NG ++PA+   T    FK GH      ++ T++ AL++G+R  D A +YG    
Sbjct: 6   KEFKLSNGNKIPAVAFGTGTKYFKRGHNDLDKQLIGTLELALRSGFRHIDGAEIYGTNKE 65

Query: 399 LNFAFKKLLPKYKLKRGDIFIISKLLPCN--YGGGAVTERAFHNTLS----NLGLDYIDL 560
           +  A K +     L R D+FI  K    N  Y G     +  +N L     +LGL+Y+DL
Sbjct: 66  IGIALKNV----GLNRKDVFITDKYNSGNHTYDGKHSKHQNPYNALKADLEDLGLEYVDL 121

Query: 561 YLVHNPGIYKLDFENRNSSRIRKQTWATLVDLYHDHKIRALGVSNYFI 704
           YL+H P I       ++      + W  L    ++   R +GVSN+ I
Sbjct: 122 YLIHFPYI-----SEKSHGFDLVEAWRYLERAKNEGLARNIGVSNFTI 164


>UniRef50_Q7G764 Cluster: Probable NAD(P)H-dependent oxidoreductase
           1; n=32; Eukaryota|Rep: Probable NAD(P)H-dependent
           oxidoreductase 1 - Oryza sativa subsp. japonica (Rice)
          Length = 321

 Score = 64.1 bits (149), Expect = 9e-09
 Identities = 49/153 (32%), Positives = 72/153 (47%), Gaps = 10/153 (6%)
 Frame = +3

Query: 270 MPAIGLDT--FKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPKYKL- 440
           MP +G+ T  F           +  A++ GYR FDTA +Y  E  +  A  + + +  + 
Sbjct: 16  MPRVGMGTAAFPFTSSEDTTAAMLRAIELGYRHFDTARIYATEGCVGEAVAEAVRRGLIA 75

Query: 441 KRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVH-----NPGIYKLDF-- 599
            R D+F+ SK+   +   G V   A   TL NLG+DY+DL LVH      PG Y   F  
Sbjct: 76  SRADVFVTSKIWCSDLHAGRVVPAA-RETLRNLGMDYVDLLLVHWPVSLTPGNYDFPFPK 134

Query: 600 ENRNSSRIRKQTWATLVDLYHDHKIRALGVSNY 698
           E    S   +  W  + + +     RA+GVSN+
Sbjct: 135 EVILPSFDMEGVWRGMEECHRLGLARAIGVSNF 167


>UniRef50_P14065 Cluster: Protein GCY; n=13; Saccharomycetales|Rep:
           Protein GCY - Saccharomyces cerevisiae (Baker's yeast)
          Length = 312

 Score = 64.1 bits (149), Expect = 9e-09
 Identities = 57/169 (33%), Positives = 81/169 (47%), Gaps = 17/169 (10%)
 Frame = +3

Query: 249 TLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLP 428
           +LN G ++P IGL T++        + V  ALK GYR  DTAA+Y NE  +  A K    
Sbjct: 13  SLNTGAQIPQIGLGTWQSKE-NDAYKAVLTALKDGYRHIDTAAIYRNEDQVGQAIKDS-- 69

Query: 429 KYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPG------IYK 590
              + R +IF+ +KL    +    V   A   +L  LGLDY+DLYL+H P       I  
Sbjct: 70  --GVPREEIFVTTKLWCTQHHEPEV---ALDQSLKRLGLDYVDLYLMHWPARLDPAYIKN 124

Query: 591 LDF----ENRNSSRIRK-------QTWATLVDLYHDHKIRALGVSNYFI 704
            D       ++ SR          +TW  + +L    K +A+GVSN+ I
Sbjct: 125 EDILSVPTKKDGSRAVDITNWNFIKTWELMQELPKTGKTKAVGVSNFSI 173


>UniRef50_Q6U5V3 Cluster: Putative uncharacterized protein; n=1;
           Klebsiella pneumoniae|Rep: Putative uncharacterized
           protein - Klebsiella pneumoniae
          Length = 279

 Score = 63.7 bits (148), Expect = 1e-08
 Identities = 49/149 (32%), Positives = 79/149 (53%)
 Frame = +3

Query: 252 LNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPK 431
           LN+G  MP  G   + + +   V   +  ALKAG+R FDTA  Y NE  +  A +     
Sbjct: 8   LNDGYYMPRPGCGLWLIDN-RDVDSLIRQALKAGFRHFDTAQAYFNEDGVGRALRYT--- 63

Query: 432 YKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLDFENRN 611
            ++ R  +FI SK+   +  G A T  +F+ TL  LG++Y++L+L+H P    +  +N  
Sbjct: 64  -EVPREQLFITSKIRGRDM-GYARTLVSFNETLERLGVEYLELFLIHWP----IPAKN-- 115

Query: 612 SSRIRKQTWATLVDLYHDHKIRALGVSNY 698
              +  +TW   ++L     IR++GVSN+
Sbjct: 116 ---LYVETWEASIELEASGLIRSIGVSNF 141


>UniRef50_A7BA05 Cluster: Putative uncharacterized protein; n=1;
           Actinomyces odontolyticus ATCC 17982|Rep: Putative
           uncharacterized protein - Actinomyces odontolyticus ATCC
           17982
          Length = 292

 Score = 63.7 bits (148), Expect = 1e-08
 Identities = 50/153 (32%), Positives = 71/153 (46%), Gaps = 2/153 (1%)
 Frame = +3

Query: 246 FTLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLL 425
           F L  G  +P +G  T+K+    T    V  AL+ GYR  DTA +YGNE  +  A    L
Sbjct: 19  FMLPTGSPIPVLGFGTYKVAPEDTY-DAVSRALEVGYRHIDTAQMYGNEAEVGAA----L 73

Query: 426 PKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVH--NPGIYKLDF 599
               + R D+FI +K+   N+        +   +L +L  DY+DL LVH   P +Y  D 
Sbjct: 74  EASGIAREDLFITTKVDNSNHEPDRAA-ASIRRSLEDLRTDYVDLLLVHWPLPTLYGGDV 132

Query: 600 ENRNSSRIRKQTWATLVDLYHDHKIRALGVSNY 698
                       W  L D ++    RA+G+SNY
Sbjct: 133 ---------ALPWPALEDAFNAGGARAIGLSNY 156


>UniRef50_Q4FY75 Cluster: Aldo-keto reductase-like protein; n=5;
           Trypanosomatidae|Rep: Aldo-keto reductase-like protein -
           Leishmania major strain Friedlin
          Length = 372

 Score = 63.7 bits (148), Expect = 1e-08
 Identities = 39/115 (33%), Positives = 57/115 (49%)
 Frame = +3

Query: 234 LPQQFTLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAF 413
           +  +  + +   +P +G  T+++         V  AL  GYR  D A  YGNE  +  A 
Sbjct: 18  ITHRIAMRDSHTIPQLGFGTYRLP-VSEATDAVAFALSCGYRHVDCAKAYGNEAAVGEAL 76

Query: 414 KKLLPKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNP 578
            + L     +R D+F+ SKL P +     V E A   TL+ L LDY+DLYL+H P
Sbjct: 77  AQALRTRCTRREDLFVTSKLWPTDQHPDHV-EAACRATLAALQLDYLDLYLIHWP 130


>UniRef50_Q2U219 Cluster: Aldo/keto reductase family proteins; n=6;
           Pezizomycotina|Rep: Aldo/keto reductase family proteins
           - Aspergillus oryzae
          Length = 294

 Score = 63.7 bits (148), Expect = 1e-08
 Identities = 48/157 (30%), Positives = 77/157 (49%), Gaps = 8/157 (5%)
 Frame = +3

Query: 252 LNNGVEMPAIGLDT----FKMGHFYTV----LQTVDDALKAGYRMFDTAALYGNEVYLNF 407
           LN+ V +P +G  T    +K     +V    ++ +  A++ GYR  D A +YG E  L  
Sbjct: 14  LNDNVSIPILGYGTGTAWYKQAGDDSVNRELVEAIKTAIRLGYRHLDGAEVYGTEAELGV 73

Query: 408 AFKKLLPKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIY 587
           A K+      + R ++F+ +K++       A    A   +L  L L+Y+DLYL+H+P   
Sbjct: 74  AIKES----GIPREELFVTTKVIT----NIADIPSAIDQSLRKLQLNYVDLYLIHSPFFA 125

Query: 588 KLDFENRNSSRIRKQTWATLVDLYHDHKIRALGVSNY 698
           K D E        +Q WA +  +    K +A+GVSNY
Sbjct: 126 KSDGE-------LQQAWAAMEKVQQAGKAKAIGVSNY 155


>UniRef50_O14088 Cluster: Xylose and arabinose reductase; n=1;
           Schizosaccharomyces pombe|Rep: Xylose and arabinose
           reductase - Schizosaccharomyces pombe (Fission yeast)
          Length = 275

 Score = 63.7 bits (148), Expect = 1e-08
 Identities = 47/149 (31%), Positives = 72/149 (48%)
 Frame = +3

Query: 252 LNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPK 431
           LNNG++ P     ++ +        +V  AL+ GYR  D+A +Y NE     A  K + +
Sbjct: 8   LNNGLKCPQFAYGSYMVNRT-KCFDSVYAALQCGYRHIDSAQMYHNEADCGRAILKFMEE 66

Query: 432 YKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLDFENRN 611
              KR DI+  SKL   +  G   T  +   ++   GL YIDL+L+H+P           
Sbjct: 67  TGTKREDIWFTSKL--NDLSGYKSTLSSIDASVKACGLGYIDLFLLHSP----------Y 114

Query: 612 SSRIRKQTWATLVDLYHDHKIRALGVSNY 698
             RI  ++W  L     + K+RA+GVSN+
Sbjct: 115 GDRI--ESWKALEKGVEEGKLRAIGVSNF 141


>UniRef50_Q9X265 Cluster: Oxidoreductase, aldo/keto reductase
           family; n=2; Thermotoga|Rep: Oxidoreductase, aldo/keto
           reductase family - Thermotoga maritima
          Length = 274

 Score = 63.3 bits (147), Expect = 2e-08
 Identities = 48/154 (31%), Positives = 76/154 (49%), Gaps = 8/154 (5%)
 Frame = +3

Query: 261 GVEMPAIGLDTFKMGHFYT--------VLQTVDDALKAGYRMFDTAALYGNEVYLNFAFK 416
           G E+PA+GL T+ +G F T        +++ +  A+K GY   DTA  YG   +      
Sbjct: 10  GEEIPALGLGTWGIGGFETPDYSRDEEMVELLKTAIKMGYTHIDTAEYYGGG-HTEELIG 68

Query: 417 KLLPKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLD 596
           K +  ++  R D+FI+SK+ P +     +  R+  NTL  L  DY+DLYL+H P      
Sbjct: 69  KAIKDFR--REDLFIVSKVWPTHLRRDDLL-RSLENTLKRLDTDYVDLYLIHWP------ 119

Query: 597 FENRNSSRIRKQTWATLVDLYHDHKIRALGVSNY 698
               N     ++T + + +      IR +GVSN+
Sbjct: 120 ----NPEIPLEETLSAMAEGVRQGLIRYIGVSNF 149


>UniRef50_Q6RZX1 Cluster: Gld1; n=22; Pezizomycotina|Rep: Gld1 -
           Trichoderma atroviride (Hypocrea atroviridis)
          Length = 327

 Score = 63.3 bits (147), Expect = 2e-08
 Identities = 53/170 (31%), Positives = 80/170 (47%), Gaps = 15/170 (8%)
 Frame = +3

Query: 246 FTLNNGVEMPAIGLDTF-KMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKL 422
           +TLN G ++PA+G  TF   G        V  AL  GYR  D A  Y NE  +  A +  
Sbjct: 15  YTLNTGAKIPAVGFGTFANEGAKGETYAAVTKALDVGYRHLDCAWFYLNEDEVGDAIRDF 74

Query: 423 LPKYK-LKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLDF 599
           L +   + R D+FI +K+    +    V   A  N+  NL +DYIDL+LVH P   + + 
Sbjct: 75  LARRPDVTRKDLFICTKVWNHLHEPEDVKWSA-KNSCENLKVDYIDLFLVHWPIAAEKNA 133

Query: 600 E-------------NRNSSRIRKQTWATLVDLYHDHKIRALGVSNYFIWG 710
           +             N+  +   + TW  + +L     ++A+GVSN+ I G
Sbjct: 134 DRTVKIGPDGKYVINKALTENPEPTWRAMEELVDSGIVKAIGVSNWTIPG 183


>UniRef50_A3VHZ9 Cluster: Oxidoreductase; n=1; Rhodobacterales
           bacterium HTCC2654|Rep: Oxidoreductase - Rhodobacterales
           bacterium HTCC2654
          Length = 278

 Score = 62.9 bits (146), Expect = 2e-08
 Identities = 40/110 (36%), Positives = 58/110 (52%)
 Frame = +3

Query: 249 TLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLP 428
           TL NGVEMP +GL T+ M       + V  A++ GYR+ DTA  Y NE  +    +    
Sbjct: 11  TLANGVEMPQLGLGTWPMTDDEAA-KAVATAIETGYRLIDTAENYKNETGVGQGIRDA-- 67

Query: 429 KYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNP 578
              + R ++F+ +K+    +       RA   +L  LGLDYIDL+L+H P
Sbjct: 68  --GVARDEVFLTTKMNK-QWHSVDGARRACEASLERLGLDYIDLFLIHWP 114


>UniRef50_Q00XM4 Cluster: Aldo/keto reductase family proteins; n=2;
           Ostreococcus|Rep: Aldo/keto reductase family proteins -
           Ostreococcus tauri
          Length = 336

 Score = 62.9 bits (146), Expect = 2e-08
 Identities = 45/146 (30%), Positives = 67/146 (45%)
 Frame = +3

Query: 261 GVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPKYKL 440
           G+ MP +   T+++    T    V DAL+ G++  DTA++YGNE  +  A +    +   
Sbjct: 59  GITMPMLAFGTYRL-RGETCRDAVRDALRCGFQHVDTASVYGNERDVGEALRACHREVSE 117

Query: 441 KRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLDFENRNSSR 620
           +   IF+ SK+ P           A       LG    DL LVH PG  K   ++     
Sbjct: 118 R---IFVTSKIAPSEMRSEEEAAAAIAGVNERLGRTP-DLVLVHWPGRDKESPDSERHRD 173

Query: 621 IRKQTWATLVDLYHDHKIRALGVSNY 698
            R+ TW  L +     + RA+GVSNY
Sbjct: 174 ARRWTWRALENALKMGQCRAIGVSNY 199


>UniRef50_Q8ZI40 Cluster: 2,5-diketo-D-gluconic acid reductase A;
           n=74; Bacteria|Rep: 2,5-diketo-D-gluconic acid reductase
           A - Yersinia pestis
          Length = 277

 Score = 62.9 bits (146), Expect = 2e-08
 Identities = 50/151 (33%), Positives = 73/151 (48%)
 Frame = +3

Query: 252 LNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPK 431
           L +G  MP +GL  ++     T L  V  AL+ GYR  DTAA+Y NE  +  A K     
Sbjct: 9   LYDGRLMPQLGLGVWQASIQETEL-AVSKALEVGYRSIDTAAIYKNEEGVGKALKAAA-- 65

Query: 432 YKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLDFENRN 611
             + R ++FI +KL   +       ++A   +L  L LDY+DLYL+H P       + + 
Sbjct: 66  --VARDELFITTKLWNDDQHN---PQQALETSLQKLQLDYVDLYLIHWP-------DPKQ 113

Query: 612 SSRIRKQTWATLVDLYHDHKIRALGVSNYFI 704
              +    W  LV L     IR++GV N+ I
Sbjct: 114 DHYV--SAWRELVTLKEQGLIRSIGVCNFHI 142


>UniRef50_UPI000155CAC7 Cluster: PREDICTED: hypothetical protein;
           n=1; Ornithorhynchus anatinus|Rep: PREDICTED:
           hypothetical protein - Ornithorhynchus anatinus
          Length = 419

 Score = 62.5 bits (145), Expect = 3e-08
 Identities = 43/137 (31%), Positives = 71/137 (51%), Gaps = 1/137 (0%)
 Frame = +3

Query: 252 LNNGVEMPAIGLDTFKMGHFYTVLQTVDDALK-AGYRMFDTAALYGNEVYLNFAFKKLLP 428
           L NG+ +P +GL T  +G +      V  ALK  G R  DTA  YG E+ L     K + 
Sbjct: 17  LANGLNIPILGLGTSHVGGYSH--DAVIYALKECGIRHIDTAKRYGCELLLG----KAIQ 70

Query: 429 KYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLDFENR 608
           +  +KR +++I +KL   +YG  +  +    +  + LG++Y+DL+L+H P         +
Sbjct: 71  ESGVKREELWITTKLWLTDYGYESAKQSCLESC-NRLGVEYLDLFLIHWP---DAQLPGK 126

Query: 609 NSSRIRKQTWATLVDLY 659
           +S   R +TW  + +LY
Sbjct: 127 SSREARAETWRAMEELY 143


>UniRef50_Q4Q973 Cluster: Aldo/keto reductase, putative; n=3;
           Leishmania|Rep: Aldo/keto reductase, putative -
           Leishmania major
          Length = 414

 Score = 62.5 bits (145), Expect = 3e-08
 Identities = 42/144 (29%), Positives = 70/144 (48%), Gaps = 1/144 (0%)
 Frame = +3

Query: 270 MPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPKYKLKRG 449
           +P IG+ T+++     V   V  AL+ GYR+ DTAA Y NE  +       +    + R 
Sbjct: 20  VPPIGIGTYELRGDACV-SAVRAALQMGYRLIDTAAAYRNEELVGEG----ISSSGVPRA 74

Query: 450 DIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLDFENRNSSR-IR 626
           D+FI+ K+   +        +   +++  L +DY D  L+H PG   L  ++ +  R  R
Sbjct: 75  DLFIVVKIAMKSMSSDEAVRQGILDSIRKLRIDYADCVLMHWPGCGGLKPQDASGHRAAR 134

Query: 627 KQTWATLVDLYHDHKIRALGVSNY 698
            + W  + +L    K+R  GVSN+
Sbjct: 135 ARCWRIMHELQALGKVRYCGVSNF 158


>UniRef50_A2EHN6 Cluster: Oxidoreductase, aldo/keto reductase family
           protein; n=10; Trichomonas vaginalis|Rep:
           Oxidoreductase, aldo/keto reductase family protein -
           Trichomonas vaginalis G3
          Length = 312

 Score = 62.5 bits (145), Expect = 3e-08
 Identities = 35/110 (31%), Positives = 57/110 (51%), Gaps = 1/110 (0%)
 Frame = +3

Query: 264 VEMPAIGLDTFKMGHFYTVLQTVDDALK-AGYRMFDTAALYGNEVYLNFAFKKLLPKYKL 440
           +E+P +G  T+       +   +  A++  G R  DTA  Y N+  +    K++  K K+
Sbjct: 1   MEIPQLGFGTYLANDPAKLKAALHYAIEECGVRHIDTAFAYYNQNVIGETLKEIFAKGKI 60

Query: 441 KRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYK 590
           KR D+FI +KL  C +    + E   H  L+ L L Y+DL+L+H P  +K
Sbjct: 61  KREDMFITTKLW-CTHHRKDLVEPELHENLAQLQLSYVDLFLIHQPIAFK 109


>UniRef50_Q4PAT5 Cluster: Putative uncharacterized protein; n=1;
           Ustilago maydis|Rep: Putative uncharacterized protein -
           Ustilago maydis (Smut fungus)
          Length = 700

 Score = 62.5 bits (145), Expect = 3e-08
 Identities = 52/168 (30%), Positives = 78/168 (46%), Gaps = 15/168 (8%)
 Frame = +3

Query: 246 FTLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLL 425
           FTL NG ++P +G  T+KM         V  A+K GYR  D A  Y NE  +    KK  
Sbjct: 12  FTLANGAQIPKLGFGTWKMSKEQAT-PAVAHAIKTGYRHIDCAWAYRNEDAVAAGIKKA- 69

Query: 426 PKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLD--- 596
               + R  +++ SKL    +    V E+A   +L +LG DY+DLYL+H P  +      
Sbjct: 70  ---GVPRSQLWLTSKLWNSFHHPEHV-EKALDASLKDLGTDYLDLYLMHWPVAFLNSKGS 125

Query: 597 ------------FENRNSSRIRKQTWATLVDLYHDHKIRALGVSNYFI 704
                        E+ + SR    T+  + ++    K+R +GVSN+ I
Sbjct: 126 MVPSIRSTGGHPVESEDLSRDFMATYRVMEEMVKKGKVRNIGVSNFNI 173


>UniRef50_Q8EVS8 Cluster: Oxidoreductase; n=1; Mycoplasma
           penetrans|Rep: Oxidoreductase - Mycoplasma penetrans
          Length = 289

 Score = 62.1 bits (144), Expect = 4e-08
 Identities = 50/154 (32%), Positives = 75/154 (48%), Gaps = 3/154 (1%)
 Frame = +3

Query: 249 TLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLP 428
           TLNNG ++P+IG   F++    T    V  A+  GYR+ DTA  Y NE       K    
Sbjct: 10  TLNNGNKIPSIGFGVFQIPKEETA-DCVKKAISIGYRLIDTAQAYHNEKETGLGIK---- 64

Query: 429 KYKLKRGDIFIISKLLPCNYGGGAVTERAFHN---TLSNLGLDYIDLYLVHNPGIYKLDF 599
              +KR +IF+ +K+   NY      ER + +   +L  L   Y+DL L+H P      F
Sbjct: 65  LSGVKREEIFLTTKVWVSNY------ERCYESVIESLKRLDTSYLDLILLHQP------F 112

Query: 600 ENRNSSRIRKQTWATLVDLYHDHKIRALGVSNYF 701
            N        + +  L  LY ++K+R +GVSN++
Sbjct: 113 GN------YYKAYQDLERLYKENKVRNIGVSNFW 140


>UniRef50_A5PDA8 Cluster: Putative oxidoreductase protein; n=1;
           Erythrobacter sp. SD-21|Rep: Putative oxidoreductase
           protein - Erythrobacter sp. SD-21
          Length = 272

 Score = 62.1 bits (144), Expect = 4e-08
 Identities = 48/149 (32%), Positives = 75/149 (50%)
 Frame = +3

Query: 252 LNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPK 431
           LN+G ++P +G  T++M       Q V  A+  GY + DTAA+YGNE        K + K
Sbjct: 9   LNDGRQIPQLGFGTWQMEE-EDAPQAVSTAIDVGYWLIDTAAIYGNE--------KGVGK 59

Query: 432 YKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLDFENRN 611
              +  DIF+ +K+   + G    T RA    L  LG +++D+ L+H P   K  F +  
Sbjct: 60  GVGEWSDIFLQTKIWNDSQGYDR-TLRAAEKCLERLGREHVDMLLIHWPCPEKDQFVD-- 116

Query: 612 SSRIRKQTWATLVDLYHDHKIRALGVSNY 698
                  TW  L++L    K +++GVSN+
Sbjct: 117 -------TWKALIELRDAGKAKSIGVSNF 138


>UniRef50_A7D6Q0 Cluster: Aldo/keto reductase; n=1; Halorubrum
           lacusprofundi ATCC 49239|Rep: Aldo/keto reductase -
           Halorubrum lacusprofundi ATCC 49239
          Length = 309

 Score = 62.1 bits (144), Expect = 4e-08
 Identities = 49/155 (31%), Positives = 80/155 (51%)
 Frame = +3

Query: 234 LPQQFTLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAF 413
           +P Q TL +G  +PA+GL T+ +     +  +V  AL +GY   DTA  Y NE     A 
Sbjct: 34  IPTQ-TLPSGDTLPALGLGTYALDDDQ-IADSVRAALSSGYTHIDTAEGYHNEE----AI 87

Query: 414 KKLLPKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKL 593
            ++L +Y   R D+F+ SK+L  N G  ++ +     +L  L  DY+DLYL+H P     
Sbjct: 88  GEVLAEYD--RDDVFLTSKVLAKNLGYESLIQSC-EASLERLETDYLDLYLIHWP----- 139

Query: 594 DFENRNSSRIRKQTWATLVDLYHDHKIRALGVSNY 698
                N +   +++   + +L+    +R +GVSN+
Sbjct: 140 -----NPAISLRESLQAMAELHDRGLVRNVGVSNF 169


>UniRef50_Q8VC28 Cluster: Aldo-keto reductase family 1 member C13;
           n=11; Theria|Rep: Aldo-keto reductase family 1 member
           C13 - Mus musculus (Mouse)
          Length = 323

 Score = 62.1 bits (144), Expect = 4e-08
 Identities = 50/160 (31%), Positives = 74/160 (46%), Gaps = 11/160 (6%)
 Frame = +3

Query: 252 LNNGVEMPAIGLDTFKMGHF--YTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLL 425
           LN+G  +PA+G  T+K         L+    AL  GYR  DTA  Y  E  +  A +  +
Sbjct: 10  LNDGHLIPALGFGTYKPKEVPKSKSLEAACLALDVGYRHVDTAYAYQVEEEIGQAIQSKI 69

Query: 426 PKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKL---D 596
               +KR D+FI +KL  C      + + A   +L  L LDY+DLY++H P   K    D
Sbjct: 70  KAGVVKREDLFITTKLW-CTCFRPELVKPALEKSLKKLQLDYVDLYIMHYPVPMKSGDND 128

Query: 597 FE-NRNSSRIRK-----QTWATLVDLYHDHKIRALGVSNY 698
           F  N     +        TW  L +      ++++GVSN+
Sbjct: 129 FPVNEQGKSLLDTVDFCDTWERLEECKDAGLVKSIGVSNF 168


>UniRef50_UPI0000E45E29 Cluster: PREDICTED: similar to aldose
           reductase; n=1; Strongylocentrotus purpuratus|Rep:
           PREDICTED: similar to aldose reductase -
           Strongylocentrotus purpuratus
          Length = 274

 Score = 61.7 bits (143), Expect = 5e-08
 Identities = 37/87 (42%), Positives = 47/87 (54%)
 Frame = +3

Query: 330 VDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPKYKLKRGDIFIISKLLPCNYGGGAVTE 509
           V  A+  GYR  D A +YGNE  +    K+      +KR DIFI SKL    +    V E
Sbjct: 16  VKAAIDCGYRHIDCAHVYGNEAEVGAGLKEKFDANVVKREDIFITSKLWNNKHHPDDV-E 74

Query: 510 RAFHNTLSNLGLDYIDLYLVHNPGIYK 590
           +A   TL NL L Y+DLYL+H P  Y+
Sbjct: 75  QACDITLKNLQLSYVDLYLMHWPMAYQ 101


>UniRef50_Q5K8C5 Cluster: Aldo-keto reductase, putative; n=1;
           Filobasidiella neoformans|Rep: Aldo-keto reductase,
           putative - Cryptococcus neoformans (Filobasidiella
           neoformans)
          Length = 303

 Score = 61.7 bits (143), Expect = 5e-08
 Identities = 47/155 (30%), Positives = 69/155 (44%)
 Frame = +3

Query: 234 LPQQFTLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAF 413
           L  +  +++G  +P  GL  ++M    T    V  AL+AGYR  DTA  Y NE     A 
Sbjct: 29  LDARLKMHDGNAIPQFGLGVYEMNDKETY-DCVKWALEAGYRHVDTAEWYENEAPCGKAI 87

Query: 414 KKLLPKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKL 593
              L      R +IF+ SKL   +    A  +     +L   G++Y DLYL+H+      
Sbjct: 88  ADFLKATGTSREEIFLTSKLKNNSSYEQAFVD--LKGSLKRSGVEYFDLYLMHSA----- 140

Query: 594 DFENRNSSRIRKQTWATLVDLYHDHKIRALGVSNY 698
                    IRK  W  L D      ++++GVSN+
Sbjct: 141 ----IGGPVIRKNVWKALCDAQSQGLVKSIGVSNF 171


>UniRef50_Q9A2X8 Cluster: Oxidoreductase, aldo/keto reductase
           family; n=3; Caulobacter|Rep: Oxidoreductase, aldo/keto
           reductase family - Caulobacter crescentus (Caulobacter
           vibrioides)
          Length = 279

 Score = 61.3 bits (142), Expect = 7e-08
 Identities = 37/105 (35%), Positives = 61/105 (58%)
 Frame = +3

Query: 264 VEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPKYKLK 443
           V MPA+G  T+++ +  T +  V+ AL+ GYR  DTA +YGNE  +  A +       +K
Sbjct: 13  VLMPALGFGTWQLENG-TAVPLVEKALEIGYRHIDTAQIYGNERDVGAAIR----NSGVK 67

Query: 444 RGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNP 578
           R +IF+ +K+    +  G + +R+   +L  LG+D +DL L+H P
Sbjct: 68  RDEIFLTTKVWIDQFADGDL-QRSAEKSLEKLGVDQVDLLLLHWP 111


>UniRef50_Q7WSY4 Cluster: Putative aldo-keto reductase; n=1;
           Propionibacterium freudenreichii subsp. shermanii|Rep:
           Putative aldo-keto reductase - Propionibacterium
           freudenreichii subsp. shermanii
          Length = 280

 Score = 61.3 bits (142), Expect = 7e-08
 Identities = 38/109 (34%), Positives = 58/109 (53%)
 Frame = +3

Query: 252 LNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPK 431
           L+ G  MP +G+ T+ +         V  A++ GYR+ DTA  YGNE  +  A ++  P 
Sbjct: 13  LSGGTRMPMLGMGTWPLKG-EECRAAVASAIEQGYRLVDTAEAYGNEEAVGKAVREAGPD 71

Query: 432 YKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNP 578
               R +IF+ +K     +    V E A  ++L  LGLDY+DL+L+H P
Sbjct: 72  ----RAEIFVTTKFSKQWHSRKGVHE-ALEHSLERLGLDYVDLFLMHWP 115


>UniRef50_Q9ZUJ6 Cluster: T2K10.1 protein; n=16; core
           eudicotyledons|Rep: T2K10.1 protein - Arabidopsis
           thaliana (Mouse-ear cress)
          Length = 176

 Score = 61.3 bits (142), Expect = 7e-08
 Identities = 40/132 (30%), Positives = 67/132 (50%), Gaps = 7/132 (5%)
 Frame = +3

Query: 324 QTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPKYKLK-RGDIFIISKLLPCNYGGGA 500
           +TV +A+K GYR FDT+  Y  E  +  A  + +    ++ R + F+ +KL   +  GG 
Sbjct: 41  ETVIEAIKLGYRHFDTSPRYQTEEPIGEALAEAVSLGLVRSRSEFFVTTKLWCADAHGGL 100

Query: 501 VTERAFHNTLSNLGLDYIDLYLVH-----NPGIYKLDFENRNSSRIR-KQTWATLVDLYH 662
           V   A   +L NL LDY+DLY++H      PG YK   +  +   +  +  W+ + +   
Sbjct: 101 VVP-AIKRSLKNLKLDYLDLYIIHWPVSSKPGKYKFPIDEDDFMPMDFEVVWSEMEECQR 159

Query: 663 DHKIRALGVSNY 698
               + +GVSN+
Sbjct: 160 LGLAKCIGVSNF 171


>UniRef50_Q7R2T6 Cluster: GLP_291_56367_57278; n=1; Giardia lamblia
           ATCC 50803|Rep: GLP_291_56367_57278 - Giardia lamblia
           ATCC 50803
          Length = 303

 Score = 61.3 bits (142), Expect = 7e-08
 Identities = 33/87 (37%), Positives = 50/87 (57%), Gaps = 2/87 (2%)
 Frame = +3

Query: 324 QTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLL--PKYKLKRGDIFIISKLLPCNYGGG 497
           + +  A+K GYR FD A  YGNE  +   FK++     Y +KR D++I+SKL P N+   
Sbjct: 19  EAIRSAVKLGYRHFDCAYRYGNERMIGEVFKEIFNDDSYGVKREDLWIVSKLWP-NFHEP 77

Query: 498 AVTERAFHNTLSNLGLDYIDLYLVHNP 578
                    TL +L L+Y+D++L+H P
Sbjct: 78  EKVAYQISETLRDLQLEYLDVFLMHWP 104


>UniRef50_Q5BKE9 Cluster: LOC594893 protein; n=5; Xenopus
           tropicalis|Rep: LOC594893 protein - Xenopus tropicalis
           (Western clawed frog) (Silurana tropicalis)
          Length = 345

 Score = 60.9 bits (141), Expect = 9e-08
 Identities = 44/129 (34%), Positives = 64/129 (49%), Gaps = 9/129 (6%)
 Frame = +3

Query: 339 ALKAGYRMFDTAALYGNEVYLNFAFKKLLPKYKLKRGDIFIISKLLPCNYGGGAVTERAF 518
           AL  GYR  D A LY +E  +  AF++      LKR D+F  SKL    +    +   A 
Sbjct: 63  ALDLGYRHVDGAFLYSSETGVGQAFREKFADGTLKREDLFYTSKLWN-TFHQPHLVRPAL 121

Query: 519 HNTLSNLGLDYIDLYLVHNPGIYK----LDFENRNSSRI-----RKQTWATLVDLYHDHK 671
             TLS L +DY+DLYL+H P  +K    L  +N + +         QTW  L +      
Sbjct: 122 EKTLSFLQMDYVDLYLIHMPMSFKPAEELFPKNEDGTCAFDQPDLLQTWQALEECRDAGL 181

Query: 672 IRALGVSNY 698
           ++++GVSN+
Sbjct: 182 VKSIGVSNF 190


>UniRef50_Q5KD52 Cluster: Oxidoreductase, putative; n=1;
           Filobasidiella neoformans|Rep: Oxidoreductase, putative
           - Cryptococcus neoformans (Filobasidiella neoformans)
          Length = 321

 Score = 60.9 bits (141), Expect = 9e-08
 Identities = 49/153 (32%), Positives = 76/153 (49%), Gaps = 3/153 (1%)
 Frame = +3

Query: 243 QFTLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAA---LYGNEVYLNFAF 413
           + TLN+G  +PAI   T+K+    T  Q V  A+  G+   DTA    +Y NE  +  A 
Sbjct: 5   EITLNDGHRIPAIAFGTWKIPKEVTPFQ-VGQAIDVGFDHIDTAQGRIVYHNEEEVGQAI 63

Query: 414 KKLLPKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKL 593
           K+      L R  +++ +K    + G GA   ++   +L  LGL+Y+DLYL+H+P + K 
Sbjct: 64  KES----GLSRNQLWVTTKWSGID-GKGA--RQSIGESLEKLGLEYLDLYLIHSPQVTKG 116

Query: 594 DFENRNSSRIRKQTWATLVDLYHDHKIRALGVS 692
           D          K  W  L  L  + K +++GVS
Sbjct: 117 DI---------KGAWKELETLQKEGKTKSIGVS 140


>UniRef50_A3T261 Cluster: Putative uncharacterized protein; n=1;
           Sulfitobacter sp. NAS-14.1|Rep: Putative uncharacterized
           protein - Sulfitobacter sp. NAS-14.1
          Length = 274

 Score = 60.1 bits (139), Expect = 2e-07
 Identities = 47/150 (31%), Positives = 72/150 (48%)
 Frame = +3

Query: 249 TLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLP 428
           TL    + P++G  TF++    TV   V  AL  G+R  DTA  Y NE  +    ++   
Sbjct: 4   TLIGPAQTPSLGFGTFQLEQD-TVADMVAAALSEGFRHIDTAQAYQNEEQVGEGLRRA-- 60

Query: 429 KYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLDFENR 608
              ++R ++F+ +K+LP ++   A T  A   +L  LG DY+DL L+H P          
Sbjct: 61  --DVRRDEVFLTTKILPEHFSPEAFTAAA-DASLKRLGTDYVDLLLLHWP---------- 107

Query: 609 NSSRIRKQTWATLVDLYHDHKIRALGVSNY 698
           +      +T   L DL    K+R  GVSN+
Sbjct: 108 SKEVPIAETIGALNDLISAGKVRHGGVSNF 137


>UniRef50_A1CAM7 Cluster: Aldo-keto reductase, putative; n=9;
           Dikarya|Rep: Aldo-keto reductase, putative - Aspergillus
           clavatus
          Length = 283

 Score = 60.1 bits (139), Expect = 2e-07
 Identities = 44/150 (29%), Positives = 74/150 (49%), Gaps = 2/150 (1%)
 Frame = +3

Query: 255 NNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPKY 434
           N+ V +P +G   ++      V Q+   AL+AGYR  DTA  Y NE  +  A    L   
Sbjct: 15  NSSVRIPRLGFGVYRSPTRQCV-QSCLTALQAGYRNIDTAQFYANEQEVGEA----LRTS 69

Query: 435 KLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLD--YIDLYLVHNPGIYKLDFENR 608
            + R D+F+ +K+L    G    T +    ++  +G +  Y+DL+L+H+         + 
Sbjct: 70  GIPRSDVFVTTKIL-SPAGSPEATYKKLLESVEKIGGENGYVDLFLIHS---------SS 119

Query: 609 NSSRIRKQTWATLVDLYHDHKIRALGVSNY 698
           + S  RK+ W  L  L  + K +++GVSN+
Sbjct: 120 SGSAGRKELWQALEKLLEEGKTKSIGVSNF 149


>UniRef50_Q11B35 Cluster: Aldo/keto reductase; n=1; Mesorhizobium
           sp. BNC1|Rep: Aldo/keto reductase - Mesorhizobium sp.
           (strain BNC1)
          Length = 253

 Score = 59.7 bits (138), Expect = 2e-07
 Identities = 49/148 (33%), Positives = 73/148 (49%), Gaps = 3/148 (2%)
 Frame = +3

Query: 270 MPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPKYKLKRG 449
           MP +GL T+++ H     +TV  A   GYRM DT+  YG +  +  A +       L R 
Sbjct: 1   MPILGLGTWQLTH--ETARTVRAAFDLGYRMVDTSGDYGTQSAIGEAIRAS----GLDRD 54

Query: 450 DIFIISKLLPCNYGGGAVTERAFHNTLSNL---GLDYIDLYLVHNPGIYKLDFENRNSSR 620
           DI++++K+          TE A++ T +NL   GLDY DL L+H P         R+ + 
Sbjct: 55  DIYLVTKV--------EETEDAYNATQANLRELGLDYADLILIHRP--------PRHGA- 97

Query: 621 IRKQTWATLVDLYHDHKIRALGVSNYFI 704
             ++ W  L+    D   R +GVSNY I
Sbjct: 98  -GEELWRALIRAREDGLTRDIGVSNYSI 124


>UniRef50_A5AD50 Cluster: Putative uncharacterized protein; n=3;
           Magnoliophyta|Rep: Putative uncharacterized protein -
           Vitis vinifera (Grape)
          Length = 304

 Score = 59.7 bits (138), Expect = 2e-07
 Identities = 33/76 (43%), Positives = 44/76 (57%)
 Frame = +3

Query: 246 FTLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLL 425
           F LN G +MP++GL T++      V Q V  A+K GYR  D A +YGNE  +    KKL 
Sbjct: 8   FQLNTGAKMPSVGLGTWQSDPGL-VGQAVAIAIKVGYRHIDCAQVYGNEEEIGIVLKKLF 66

Query: 426 PKYKLKRGDIFIISKL 473
               +KR D++I SKL
Sbjct: 67  DDGVVKREDLWITSKL 82


>UniRef50_A3C1Z7 Cluster: Putative uncharacterized protein; n=2;
           Oryza sativa (japonica cultivar-group)|Rep: Putative
           uncharacterized protein - Oryza sativa subsp. japonica
           (Rice)
          Length = 288

 Score = 59.7 bits (138), Expect = 2e-07
 Identities = 50/162 (30%), Positives = 79/162 (48%), Gaps = 13/162 (8%)
 Frame = +3

Query: 252 LNNGVEMPAIGLDT--FKMGHF--YTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKK 419
           L++G  MP +G+ T  F +G     TV   V  A++AGYR FDTAA+Y  E  L  A  +
Sbjct: 6   LSSGKPMPRVGMGTASFPLGATDPSTVKDVVLRAIEAGYRHFDTAAVYQTEAILGDAVAE 65

Query: 420 LL-PKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKL- 593
            +       R +++I SKL   +   G V   +    L  + ++Y+DLYL+H P   +L 
Sbjct: 66  AVRAGLVASRDELYITSKLWVAHAHPGHVLP-SLRRALRKMQMEYLDLYLIHFPVSMRLA 124

Query: 594 -DFENRNSSR------IRKQTWATLVDLYHDHKIRALGVSNY 698
            D E+   S+        +  W  + +       +A+GVSN+
Sbjct: 125 EDPESMTYSKDDLVMMDMEGVWKEMEECQRLGLTKAIGVSNF 166


>UniRef50_UPI0000D9A956 Cluster: PREDICTED: similar to aldo-keto
           reductase family 1, member B10, partial; n=1; Macaca
           mulatta|Rep: PREDICTED: similar to aldo-keto reductase
           family 1, member B10, partial - Macaca mulatta
          Length = 275

 Score = 59.3 bits (137), Expect = 3e-07
 Identities = 34/96 (35%), Positives = 54/96 (56%), Gaps = 5/96 (5%)
 Frame = +3

Query: 318 VLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPKYKLKRGDIFIISKL-----LPC 482
           V + V  A+ AGYR  D A +Y NE  +  A ++ + +  +KR D+FI+SK+     L  
Sbjct: 48  VKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEKIQEQAVKREDLFIVSKVHMAHWLWT 107

Query: 483 NYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYK 590
            +    +  +AF  TL +L L Y+D+YL+H P  +K
Sbjct: 108 TFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFK 143


>UniRef50_Q6F7K7 Cluster: 2,5-diketo-D-gluconate reductase; n=20;
           Bacteria|Rep: 2,5-diketo-D-gluconate reductase -
           Acinetobacter sp. (strain ADP1)
          Length = 297

 Score = 59.3 bits (137), Expect = 3e-07
 Identities = 47/149 (31%), Positives = 70/149 (46%)
 Frame = +3

Query: 252 LNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPK 431
           L++G  +PA+G  T+ +     V  T+  AL  GYRM D+A  Y NE  +  A ++    
Sbjct: 27  LHDGHSIPALGFGTYTLKGQQGV-DTMLRALGHGYRMLDSAFNYENEGAVGAAVRQS--- 82

Query: 432 YKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLDFENRN 611
             L R +IFI SKL P  +            +L  +  DY+DLYL+H P           
Sbjct: 83  -GLLRDEIFITSKL-PGRHHAYDKAMETIEESLYRMQFDYLDLYLIHWP---------NP 131

Query: 612 SSRIRKQTWATLVDLYHDHKIRALGVSNY 698
              +  + W  L+D      IR++GVSN+
Sbjct: 132 QQGLYIEAWQALIDAQKKGYIRSIGVSNF 160


>UniRef50_Q9U2J5 Cluster: Putative uncharacterized protein; n=2;
           Caenorhabditis|Rep: Putative uncharacterized protein -
           Caenorhabditis elegans
          Length = 339

 Score = 58.8 bits (136), Expect = 3e-07
 Identities = 46/166 (27%), Positives = 79/166 (47%), Gaps = 14/166 (8%)
 Frame = +3

Query: 249 TLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLP 428
           TLN+G EMP IG  T+++       + V DAL+AGYR  D+A  + N+  +    K    
Sbjct: 8   TLNSGYEMPVIGYGTWQLPKNLAA-ERVRDALEAGYRHIDSALSFKNQEEVAAGIKDWCK 66

Query: 429 KYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNP---------- 578
             K++R ++F+ SK+    +      ++     L      Y+DL ++H P          
Sbjct: 67  IRKVRREELFLSSKIWNTYHSRNRCMQQ-IDEMLEIFETTYMDLIVIHWPFGWAEDEPPG 125

Query: 579 --GIYK--LDFENRNSSRIRKQTWATLVDLYHDHKIRALGVSNYFI 704
             G++    + + R S     +TW  L D +   KIR++G++N+ I
Sbjct: 126 ERGLWPRGANGKMRYSDVDYLETWKALEDAHRSGKIRSIGLANFNI 171


>UniRef50_A6RMS0 Cluster: Putative uncharacterized protein; n=1;
           Botryotinia fuckeliana B05.10|Rep: Putative
           uncharacterized protein - Botryotinia fuckeliana B05.10
          Length = 286

 Score = 58.8 bits (136), Expect = 3e-07
 Identities = 54/155 (34%), Positives = 74/155 (47%), Gaps = 2/155 (1%)
 Frame = +3

Query: 246 FTLNNGVEMPAIGLDTFKMGHFYT-VLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKL 422
           F L NG  +PAIGL TF+       V   V  A++AGYR  D AA YGNE  +  A K  
Sbjct: 8   FRLVNGSTLPAIGLGTFQGDDGNEKVKNIVKAAIQAGYRHIDGAAAYGNEEAIGDAIK-- 65

Query: 423 LPKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYI-DLYLVHNPGIYKLDF 599
             +  + R +       L   +      ERA   +L  LGL+Y+   YL   PG   +D+
Sbjct: 66  --ESGISRDE-------LAQPWHEPKDVERALDLSLEALGLEYVPHAYL---PGPNNVDY 113

Query: 600 ENRNSSRIRKQTWATLVDLYHDHKIRALGVSNYFI 704
           E    SR   +TW  +  L    K +A+G+SN+ I
Sbjct: 114 ER---SRKYTETWQAMEKLVDSGKAKAIGLSNFNI 145


>UniRef50_Q5UYI9 Cluster: Oxidoreductase; n=1; Haloarcula
           marismortui|Rep: Oxidoreductase - Haloarcula marismortui
           (Halobacterium marismortui)
          Length = 264

 Score = 58.8 bits (136), Expect = 3e-07
 Identities = 47/128 (36%), Positives = 64/128 (50%)
 Frame = +3

Query: 315 TVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPKYKLKRGDIFIISKLLPCNYGG 494
           TV ++V   L  GY   DTA  Y NE  +  A    L  Y   R D+F+ SK+LP +   
Sbjct: 13  TVQKSVRAGLNVGYAHVDTAEGYKNESEIGEA----LADYD--REDVFLTSKVLPKHLDY 66

Query: 495 GAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLDFENRNSSRIRKQTWATLVDLYHDHKI 674
            +V E A   +L  LG DY+DLYLVH P          N +   ++T   +  L+   KI
Sbjct: 67  ESVIE-ACEASLDRLGTDYLDLYLVHWP----------NPATSIRETMNAMATLHDQGKI 115

Query: 675 RALGVSNY 698
           R +GVSN+
Sbjct: 116 RNVGVSNF 123


>UniRef50_P51857 Cluster: 3-oxo-5-beta-steroid 4-dehydrogenase (EC
           1.3.1.3) (Delta(4)-3- ketosteroid 5-beta-reductase);
           n=124; cellular organisms|Rep: 3-oxo-5-beta-steroid
           4-dehydrogenase (EC 1.3.1.3) (Delta(4)-3- ketosteroid
           5-beta-reductase) - Homo sapiens (Human)
          Length = 326

 Score = 58.8 bits (136), Expect = 3e-07
 Identities = 48/161 (29%), Positives = 75/161 (46%), Gaps = 12/161 (7%)
 Frame = +3

Query: 252 LNNGVEMPAIGLDTF---KMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKL 422
           L++G  +P IGL T+   K         +V  A+  GYR  D A +Y NE  +  A ++ 
Sbjct: 12  LSDGNSIPIIGLGTYSEPKSTPKGACATSVKVAIDTGYRHIDGAYIYQNEHEVGEAIREK 71

Query: 423 LPKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLDFE 602
           + + K++R DIF   KL   N+    V       TL  L LDY+DLY++  P  +K   E
Sbjct: 72  IAEGKVRREDIFYCGKLWATNHVPEMV-RPTLERTLRVLQLDYVDLYIIEVPMAFKPGDE 130

Query: 603 ----NRNSSRIRKQ-----TWATLVDLYHDHKIRALGVSNY 698
               + N   +  +     TW  +        +++LGVSN+
Sbjct: 131 IYPRDENGKWLYHKSNLCATWEAMEACKDAGLVKSLGVSNF 171


>UniRef50_Q8ET73 Cluster: 2,5-diketo-D-gluconate reductase; n=12;
           Bacteria|Rep: 2,5-diketo-D-gluconate reductase -
           Oceanobacillus iheyensis
          Length = 280

 Score = 58.4 bits (135), Expect = 5e-07
 Identities = 44/150 (29%), Positives = 70/150 (46%)
 Frame = +3

Query: 249 TLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLP 428
           TL++G+ +P +G  T+++     V Q +++A+  GYR+ DTA  Y NE  +  A +    
Sbjct: 9   TLHDGLTIPKVGFGTYRLNGNDGV-QAINNAIDHGYRLIDTAYNYENEGTVGEAVR---- 63

Query: 429 KYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLDFENR 608
           +    R  + I SK LP  Y            +L    LDY DLYL+H P   +      
Sbjct: 64  RSSTPREQLLITSK-LPGRYHHYDKAVTTIQESLYRANLDYYDLYLIHWPNPIQ------ 116

Query: 609 NSSRIRKQTWATLVDLYHDHKIRALGVSNY 698
               I  + W  L++      IR++GV N+
Sbjct: 117 ---DIYVEAWQALIEAKRRGYIRSIGVCNF 143


>UniRef50_Q0GU15 Cluster: ORF28; n=3; Bacteria|Rep: ORF28 -
           Lactococcus lactis
          Length = 281

 Score = 58.4 bits (135), Expect = 5e-07
 Identities = 45/147 (30%), Positives = 69/147 (46%), Gaps = 4/147 (2%)
 Frame = +3

Query: 270 MPAIGLDTFKMGHFYTV----LQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPKYK 437
           +PAIGL T+ MG+        ++ +   + AG  + DTA +YGN    +   + +     
Sbjct: 11  VPAIGLGTWHMGNSTATRAKEIKAIQAGIDAGATVIDTAEMYGNGRSESLVGEAIA---N 67

Query: 438 LKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLDFENRNSS 617
           + R  +F+I K+LP N     ++  +   +L  LG DY+DLYL H  G   L        
Sbjct: 68  IDREKLFLIDKVLPSNASADRMSH-SLDTSLKLLGTDYVDLYLYHWRGAVPL-------- 118

Query: 618 RIRKQTWATLVDLYHDHKIRALGVSNY 698
               +T  TL  L    KI+  GVSN+
Sbjct: 119 ---SETVETLQSLQQQGKIKHWGVSNF 142


>UniRef50_Q8K023 Cluster: Aldo-keto reductase family 1 member C18;
           n=72; Tetrapoda|Rep: Aldo-keto reductase family 1 member
           C18 - Mus musculus (Mouse)
          Length = 323

 Score = 58.4 bits (135), Expect = 5e-07
 Identities = 36/115 (31%), Positives = 56/115 (48%), Gaps = 2/115 (1%)
 Frame = +3

Query: 240 QQFTLNNGVEMPAIGLDTFKMGHFYTV--LQTVDDALKAGYRMFDTAALYGNEVYLNFAF 413
           Q+  LN+G  +P +G  T+          +++   A+  G+   D + LY NE  +  A 
Sbjct: 6   QKIELNDGHSIPVLGFGTYATEEHLKKKSMESTKIAIDVGFCHIDCSHLYQNEEEIGQAI 65

Query: 414 KKLLPKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNP 578
              +    +KR DIF  SKL   ++    V   +  N+L  L LDY+DLYL+H P
Sbjct: 66  LSKIEDGTVKREDIFYTSKLWSTSHRPELVRP-SLENSLRKLNLDYVDLYLIHFP 119


>UniRef50_A3UJS6 Cluster: Oxidoreductase; n=3;
           Alphaproteobacteria|Rep: Oxidoreductase - Oceanicaulis
           alexandrii HTCC2633
          Length = 275

 Score = 58.0 bits (134), Expect = 6e-07
 Identities = 36/110 (32%), Positives = 58/110 (52%)
 Frame = +3

Query: 249 TLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLP 428
           T  NG ++P +G  T+++       + V  ALK GYR  DTA +YGNE  +   +K    
Sbjct: 5   TQANGADIPKLGFGTWQLED-EDAARGVATALKTGYRHIDTAQIYGNEAAVGDGWK---- 59

Query: 429 KYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNP 578
           +  +KR D F+ +K+    +  G + + +   +L  L  DY+DL L+H P
Sbjct: 60  QSGVKREDFFLTTKVWRDKFRDGDL-QASVKESLDKLKTDYVDLLLLHWP 108


>UniRef50_Q01J82 Cluster: OSIGBa0152K17.5 protein; n=28;
           Magnoliophyta|Rep: OSIGBa0152K17.5 protein - Oryza
           sativa (Rice)
          Length = 323

 Score = 58.0 bits (134), Expect = 6e-07
 Identities = 46/155 (29%), Positives = 72/155 (46%), Gaps = 9/155 (5%)
 Frame = +3

Query: 261 GVEMPAIGLDTFKMGHFY--TVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPK- 431
           G  MPA+G+ T         T       AL+ G+R FDTAALYG E  L  A  +   + 
Sbjct: 14  GRPMPAVGVGTADSAATSPETKRGAALAALEVGFRHFDTAALYGTEAPLGEAIAEATRRG 73

Query: 432 YKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVH-----NPGIYKLD 596
               R ++F+ +KL  C      +   +   +L NL ++Y+DLYLVH      PG   L 
Sbjct: 74  LVASREEVFVTTKLW-CTQCHPGLVLPSLRESLRNLQMEYVDLYLVHWPISVKPGPPMLP 132

Query: 597 FENRNSSRIR-KQTWATLVDLYHDHKIRALGVSNY 698
            +  ++     +  W  + + +     +A+GVSN+
Sbjct: 133 VKREDAVPFDFEGVWRAMEECHRLGLAKAIGVSNF 167


>UniRef50_P91021 Cluster: Putative uncharacterized protein; n=1;
           Caenorhabditis elegans|Rep: Putative uncharacterized
           protein - Caenorhabditis elegans
          Length = 134

 Score = 58.0 bits (134), Expect = 6e-07
 Identities = 29/75 (38%), Positives = 48/75 (64%)
 Frame = +3

Query: 249 TLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLP 428
           TL+N   MPA+GL T++  +   V+  V  A+K GY + DTA+ Y NE ++  A K+++ 
Sbjct: 49  TLSNAHSMPAVGLGTWQ-SNAEDVISAVKAAVKNGYSLIDTASGYNNEEFIGTAIKEVIA 107

Query: 429 KYKLKRGDIFIISKL 473
           +  +KR D+FI +K+
Sbjct: 108 EGVVKREDLFITTKV 122


>UniRef50_Q4V008 Cluster: Oxidoreductase; n=4; Proteobacteria|Rep:
           Oxidoreductase - Xanthomonas campestris pv. campestris
           (strain 8004)
          Length = 267

 Score = 57.6 bits (133), Expect = 8e-07
 Identities = 44/145 (30%), Positives = 71/145 (48%)
 Frame = +3

Query: 270 MPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPKYKLKRG 449
           +PA GL TF++     V+ +V +AL  GYR  DTA +Y NE  +  A    +    + R 
Sbjct: 3   VPAFGLGTFRLKD-QVVIDSVRNALALGYRAIDTAQIYDNEAQVGQA----IADAGVPRD 57

Query: 450 DIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLDFENRNSSRIRK 629
            +F+ +K+    +    + + +   +L  LG DY+DL L+H P         ++   +R+
Sbjct: 58  QLFVTTKIWVDRFSRDTL-QPSLQESLRKLGTDYVDLTLIHWP-------SPKDQVPMRE 109

Query: 630 QTWATLVDLYHDHKIRALGVSNYFI 704
              A L D       RA+GVSN+ I
Sbjct: 110 YLEA-LADAKAQGLTRAIGVSNFTI 133


>UniRef50_Q4Q5X1 Cluster: Aldehyde reductase, putative; n=75;
           cellular organisms|Rep: Aldehyde reductase, putative -
           Leishmania major
          Length = 286

 Score = 57.6 bits (133), Expect = 8e-07
 Identities = 47/153 (30%), Positives = 71/153 (46%), Gaps = 4/153 (2%)
 Frame = +3

Query: 252 LNNGVEMPAIGLDTFKMGHF----YTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKK 419
           L +G   PA+G   + MG         L  +   ++AG  + DTA +YGN        + 
Sbjct: 9   LPDGTAAPALGQGVWMMGETPENRTRELAALRAGMEAGMTLIDTAEMYGNGRSERLVAEA 68

Query: 420 LLPKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLDF 599
           +    +  R  +FI+SK+LP N    A+  R+   +L N+G DY+DLYL+H  G   L  
Sbjct: 69  IK---ETPRERLFIVSKVLPTNASRAAIF-RSCDASLQNIGTDYLDLYLLHWRGRVPL-- 122

Query: 600 ENRNSSRIRKQTWATLVDLYHDHKIRALGVSNY 698
                     +T   + +L    KIR  GVSN+
Sbjct: 123 ---------SETVTCMEELVKSGKIRRWGVSNF 146


>UniRef50_UPI0000499B0E Cluster: oxidoreductase, aldo/keto reductase
           family; n=1; Entamoeba histolytica HM-1:IMSS|Rep:
           oxidoreductase, aldo/keto reductase family - Entamoeba
           histolytica HM-1:IMSS
          Length = 307

 Score = 57.2 bits (132), Expect = 1e-06
 Identities = 49/164 (29%), Positives = 77/164 (46%), Gaps = 6/164 (3%)
 Frame = +3

Query: 231 ILPQQFTLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYL-NF 407
           +L   F LNNG  MPAIGL T+ +     V + V  AL+ GYR+ D A  Y NE  +   
Sbjct: 1   MLQHGFFLNNGKFMPAIGLGTW-LAAPGEVGKAVTLALENGYRLIDCARFYKNEKEIGEM 59

Query: 408 AFKKLLPKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIY 587
             +  L  +   R ++F+ SKL         + E     ++ +L   Y+DLYL+H P   
Sbjct: 60  GIEPFLKNH--PREELFVTSKLWMDQV--TRIRESCL-ESIQDLKCKYLDLYLIHWPIAL 114

Query: 588 KLDFENRNS-----SRIRKQTWATLVDLYHDHKIRALGVSNYFI 704
           K+D  N             + W  +  L  +  ++++G+SN+ I
Sbjct: 115 KVDASNPPKPEDFLDMDITEIWQEMERLVDEGLVKSIGLSNFTI 158


>UniRef50_A6WDZ5 Cluster: Aldo/keto reductase; n=5; Bacteria|Rep:
           Aldo/keto reductase - Kineococcus radiotolerans SRS30216
          Length = 343

 Score = 57.2 bits (132), Expect = 1e-06
 Identities = 37/111 (33%), Positives = 57/111 (51%), Gaps = 2/111 (1%)
 Frame = +3

Query: 252 LNNGVEMPAIGLDTFKMGHFYT--VLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLL 425
           L  G  +PAIG+ TF    +    V   V  A+ AGYR+ D AA+YGNE  +  A    +
Sbjct: 18  LRGGATVPAIGIGTFGSDRYSPAEVAAAVAGAVAAGYRLVDCAAVYGNEAQVGEALAGAV 77

Query: 426 PKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNP 578
               + R ++F++SK+   +    A    + H +L +L LD++D   VH P
Sbjct: 78  AG-GVDRDELFVVSKVWN-DAHAPADAVASVHRSLRDLRLDHLDAVFVHWP 126


>UniRef50_UPI00015B4912 Cluster: PREDICTED: similar to aldo-keto
           reductase; n=1; Nasonia vitripennis|Rep: PREDICTED:
           similar to aldo-keto reductase - Nasonia vitripennis
          Length = 353

 Score = 56.8 bits (131), Expect = 1e-06
 Identities = 40/112 (35%), Positives = 56/112 (50%), Gaps = 1/112 (0%)
 Frame = +3

Query: 246 FTLNNGVEMPAIGLDTFKMGHFYTVLQTV-DDALKAGYRMFDTAALYGNEVYLNFAFKKL 422
           + L++G   P +GL T  +     VL+TV   AL+ G    DT+ +Y NE  +    K  
Sbjct: 31  YRLSSGHNFPIVGLGTHGLNE--DVLETVLTGALEKGIGHIDTSFVYKNEETIGKVLKDW 88

Query: 423 LPKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNP 578
             K   KR DIF+ SKL P         E+    +L  LGL Y+D+YL+H P
Sbjct: 89  FAKGG-KREDIFVTSKL-PYYDNHPESVEKYIKLSLEKLGLQYLDMYLIHAP 138


>UniRef50_Q11DV1 Cluster: Aldo/keto reductase; n=10;
           Alphaproteobacteria|Rep: Aldo/keto reductase -
           Mesorhizobium sp. (strain BNC1)
          Length = 274

 Score = 56.8 bits (131), Expect = 1e-06
 Identities = 35/107 (32%), Positives = 56/107 (52%)
 Frame = +3

Query: 258 NGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPKYK 437
           +G  +PA+G   F+M     V + +  AL+AG+R FDTA +Y NE     A  + L +  
Sbjct: 7   HGATIPALGFGVFRMSDA-EVERIIPAALEAGFRHFDTAQIYQNEA----ALGRALERAG 61

Query: 438 LKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNP 578
            +R D+F+ +K+   NY        +   +L  L +D +DL L+H P
Sbjct: 62  ARREDLFLTTKVWVDNYSADKFA-ASVDESLEKLKVDQVDLLLLHWP 107


>UniRef50_Q0SFM4 Cluster: Probable 2,5-didehydrogluconate reductase;
           n=1; Rhodococcus sp. RHA1|Rep: Probable
           2,5-didehydrogluconate reductase - Rhodococcus sp.
           (strain RHA1)
          Length = 265

 Score = 56.8 bits (131), Expect = 1e-06
 Identities = 34/105 (32%), Positives = 59/105 (56%)
 Frame = +3

Query: 264 VEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPKYKLK 443
           +++P +GL T+ +       + V   ++AGYR+ DTA +Y NE  +  A    L +  + 
Sbjct: 2   MDIPPLGLGTWPLTG-PDATRAVLSGIEAGYRLIDTATIYDNEDAVGVA----LAECGVP 56

Query: 444 RGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNP 578
           R ++F+ +KL   ++  G +   A   +L NLGLD +DL+L+H P
Sbjct: 57  REELFVTTKLRGSDHVSGDI-RGAVERSLKNLGLDRLDLFLIHWP 100


>UniRef50_A2EYY6 Cluster: Oxidoreductase, aldo/keto reductase family
           protein; n=9; Trichomonas vaginalis G3|Rep:
           Oxidoreductase, aldo/keto reductase family protein -
           Trichomonas vaginalis G3
          Length = 308

 Score = 56.8 bits (131), Expect = 1e-06
 Identities = 38/104 (36%), Positives = 56/104 (53%), Gaps = 1/104 (0%)
 Frame = +3

Query: 270 MPAIGLDTFKMGHFYTVLQTVDDALK-AGYRMFDTAALYGNEVYLNFAFKKLLPKYKLKR 446
           +P IGL T+K      ++  +  A+K AGY   D A  Y NE  +  A ++      +KR
Sbjct: 4   IPTIGLGTWKSPRSEDLVNAITYAIKEAGYVHIDCALCYENEDIVGQALQQCWDS-GIKR 62

Query: 447 GDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNP 578
            +I+I SKL   ++    + E A   TL +L LDY+DLYL+H P
Sbjct: 63  ENIWITSKLWNTHHRL-EIVEEACRKTLKDLRLDYLDLYLMHYP 105


>UniRef50_A6SJ74 Cluster: Putative uncharacterized protein; n=1;
           Botryotinia fuckeliana B05.10|Rep: Putative
           uncharacterized protein - Botryotinia fuckeliana B05.10
          Length = 166

 Score = 56.8 bits (131), Expect = 1e-06
 Identities = 44/113 (38%), Positives = 57/113 (50%), Gaps = 2/113 (1%)
 Frame = +3

Query: 366 DTAALYGNEVYLNFAFKKLLPKYKLKRGDIFIISKLLP--CNYGGGAVTERAFHNTLSNL 539
           D+AA Y NE     A +K      + R DIF  SK+ P   +Y     T+     TL   
Sbjct: 5   DSAAAYRNEGPCAIAIQKS----SIPREDIFFTSKIPPRALSYEN---TKAQVAKTLMET 57

Query: 540 GLDYIDLYLVHNPGIYKLDFENRNSSRIRKQTWATLVDLYHDHKIRALGVSNY 698
           GLDYIDL L+H P      +  R++   RK  W  LV+   + KIR+LGVSNY
Sbjct: 58  GLDYIDLMLIHAP------YGGRDA---RKGAWKALVEAQEEGKIRSLGVSNY 101


>UniRef50_Q6CEJ0 Cluster: Yarrowia lipolytica chromosome B of strain
           CLIB122 of Yarrowia lipolytica; n=1; Yarrowia
           lipolytica|Rep: Yarrowia lipolytica chromosome B of
           strain CLIB122 of Yarrowia lipolytica - Yarrowia
           lipolytica (Candida lipolytica)
          Length = 302

 Score = 56.4 bits (130), Expect = 2e-06
 Identities = 47/156 (30%), Positives = 72/156 (46%), Gaps = 7/156 (4%)
 Frame = +3

Query: 252 LNNGVEMPAIGLDT---FKMG----HFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFA 410
           L+NG+E+PAIG  +   +K          ++  V  A+ AG+   DTA  YG E  +  A
Sbjct: 8   LSNGLEIPAIGFGSGTKWKRPPGEKEERELIDAVVSAINAGHLHIDTAEFYGTEKQIGEA 67

Query: 411 FKKLLPKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYK 590
            K    +  + R DIF+ SK L        +   +  N L  L  DY DL+L+H P    
Sbjct: 68  IK----ESGVPRKDIFLTSKTLFGLLADDPI--ESISNQLKTLQTDYFDLFLIHVPPNDD 121

Query: 591 LDFENRNSSRIRKQTWATLVDLYHDHKIRALGVSNY 698
           ++++         + W  L  LY     +A+GVSN+
Sbjct: 122 INYD-------LAKAWGVLEQLYEKGLAKAIGVSNH 150


>UniRef50_Q59Z55 Cluster: Potential aldo/keto reductase; n=6;
           Saccharomycetales|Rep: Potential aldo/keto reductase -
           Candida albicans (Yeast)
          Length = 319

 Score = 56.4 bits (130), Expect = 2e-06
 Identities = 36/114 (31%), Positives = 60/114 (52%), Gaps = 3/114 (2%)
 Frame = +3

Query: 246 FTLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLL 425
           + LNNG  +P IG  T+ +        T   ALK GYR  DTA  Y NE  ++   K+ L
Sbjct: 16  YKLNNGSHIPVIGFGTYLLDASQAADLTYQ-ALKDGYRHIDTALAYHNEKEVSQGIKRFL 74

Query: 426 PKY-KLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNL--GLDYIDLYLVHNP 578
             + +++R DI+  +K +     G   T++A     +++   ++Y+DL L+H+P
Sbjct: 75  KDHPEVQRSDIWFTTK-IDTQSLGYEETKKAVERIKNDVKDNIEYVDLILIHSP 127


>UniRef50_Q9HM42 Cluster: Alcohol dehydrogenase related protein;
           n=1; Thermoplasma acidophilum|Rep: Alcohol dehydrogenase
           related protein - Thermoplasma acidophilum
          Length = 284

 Score = 56.4 bits (130), Expect = 2e-06
 Identities = 43/149 (28%), Positives = 74/149 (49%), Gaps = 1/149 (0%)
 Frame = +3

Query: 261 GVEMPAIGLDTFKM-GHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPKYK 437
           G ++  IG+ T+ + G     ++++  AL  G    DTA +YG E  +  A K       
Sbjct: 13  GRKVSVIGVGTWSLEGSRSENVRSIRYALDHGVNFIDTAEMYGTEDIVGEAIKGY----- 67

Query: 438 LKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLDFENRNSS 617
            +R D+FI +K+ P ++    V  ++   +L  LG DY+DLY +H P          N S
Sbjct: 68  -RREDLFIATKVWPTHFAYHDVL-KSCEESLKKLGTDYVDLYQLHWP----------NPS 115

Query: 618 RIRKQTWATLVDLYHDHKIRALGVSNYFI 704
              K+T + +  L  + +IR +G+SN+ +
Sbjct: 116 VSIKETMSAMEKLVDEGRIRYIGISNFSV 144


>UniRef50_Q5NLW3 Cluster: Putative oxidoreductase; n=1; Zymomonas
           mobilis|Rep: Putative oxidoreductase - Zymomonas mobilis
          Length = 273

 Score = 56.0 bits (129), Expect = 2e-06
 Identities = 46/151 (30%), Positives = 70/151 (46%)
 Frame = +3

Query: 252 LNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPK 431
           LN+G  MPAIG   +++         V      GYR  DTAA Y NE  +    +     
Sbjct: 9   LNDGHSMPAIGQGVYQLNPAQAE-SMVALGYDLGYRAVDTAAWYENEEGVGEGLRS---- 63

Query: 432 YKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLDFENRN 611
              +    FI +KL+P + G       A   ++ NLG+  ++LYL+H PG  +  +E   
Sbjct: 64  ---RHARSFITTKLMPQDMGRVNCFV-ALDKSIRNLGVTSLNLYLIHWPGQDRKRYE--- 116

Query: 612 SSRIRKQTWATLVDLYHDHKIRALGVSNYFI 704
                 +TW TL+ +    K  ++GVSN+ I
Sbjct: 117 ------ETWQTLIQIRAIGKASSIGVSNFTI 141


>UniRef50_A7P424 Cluster: Chromosome chr1 scaffold_5, whole genome
           shotgun sequence; n=1; Vitis vinifera|Rep: Chromosome
           chr1 scaffold_5, whole genome shotgun sequence - Vitis
           vinifera (Grape)
          Length = 247

 Score = 56.0 bits (129), Expect = 2e-06
 Identities = 50/168 (29%), Positives = 78/168 (46%), Gaps = 13/168 (7%)
 Frame = +3

Query: 234 LPQQFTLNNGVEMPAIGLDT--FKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNF 407
           +P+    + G  +P +G+ T  +      T++ ++  A++ GYR FD  A Y +E  L  
Sbjct: 4   IPEMTLGSTGKAIPLVGMVTTVYPFAPSETMIDSILTAIELGYRHFDCVAAYLSEKPLGE 63

Query: 408 AFKKLLPKYKLK-RGDIFIISKLLPCNYGGGAVTERAFHNTLS---------NLGLDYID 557
           A KK +    +K R ++FI SKL  C+         A  NTL          NL LDY+D
Sbjct: 64  AIKKAVKLGLIKSRDELFITSKLW-CSDAHHDRVLPALQNTLKISSILSFSKNLQLDYLD 122

Query: 558 LYLVH-NPGIYKLDFENRNSSRIRKQTWATLVDLYHDHKIRALGVSNY 698
           LYL+H + G   +D  +          W  + D       +A+GVSN+
Sbjct: 123 LYLIHWSDGHLPIDLGS---------VWKAMEDFQKLSLTKAIGVSNF 161


>UniRef50_Q76L36 Cluster: Conjugated polyketone reductase C2; n=1;
           Candida parapsilosis|Rep: Conjugated polyketone
           reductase C2 - Candida parapsilosis (Yeast)
          Length = 307

 Score = 56.0 bits (129), Expect = 2e-06
 Identities = 48/168 (28%), Positives = 79/168 (47%), Gaps = 13/168 (7%)
 Frame = +3

Query: 231 ILPQQFTLNNGVEMP-AIGLDT-FKMGHFYTVLQT--VDD---ALKAGYRMFDTAALYGN 389
           +LP+ F   +G E+  A+G  T +K       + T  VD+    LK G+R  DTA  Y  
Sbjct: 6   LLPKTFRTKSGKEISIALGTGTKWKQAQTINDVSTELVDNILLGLKLGFRHIDTAEAYNT 65

Query: 390 EVYLNFAFKKLLPKYKLKRGDIFIISKLLPCNYGGGAVT------ERAFHNTLSNLGLDY 551
           +  +  A K+      + R DI++ +K  P   G G++         +    L+ LG+DY
Sbjct: 66  QKEVGEALKRT----DVPREDIWVTTKYSP---GWGSIKAYSKSPSDSIDKALAQLGVDY 118

Query: 552 IDLYLVHNPGIYKLDFENRNSSRIRKQTWATLVDLYHDHKIRALGVSN 695
           +DL+L+H+P         +      +Q W  LV+     K+R +G+SN
Sbjct: 119 VDLFLIHSP----FFTTEQTHGYTLEQAWEALVEAKKAGKVREIGISN 162


>UniRef50_A7D7K7 Cluster: Aldo/keto reductase; n=1; Halorubrum
           lacusprofundi ATCC 49239|Rep: Aldo/keto reductase -
           Halorubrum lacusprofundi ATCC 49239
          Length = 265

 Score = 56.0 bits (129), Expect = 2e-06
 Identities = 41/112 (36%), Positives = 57/112 (50%), Gaps = 1/112 (0%)
 Frame = +3

Query: 264 VEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPKYKLK 443
           +E+P +GL T ++        TV  AL+AGYR  DTA +Y NE     A  + +    + 
Sbjct: 4   LELP-LGLGTSRLDDPAECRATVAAALEAGYRHVDTAQMYDNET----AVGEGIATADVD 58

Query: 444 RGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNP-GIYKLD 596
           R D+ + +K+ P N     V E A   +L  LGLD +DL  VH P G Y  D
Sbjct: 59  RDDVVVATKIHPDNLAPADVRETA-RKSLDRLGLDRVDLLYVHWPTGAYDPD 109


>UniRef50_Q5T2L2 Cluster: Aldo-keto reductase family 1 member C-like
           protein 1; n=14; Eutheria|Rep: Aldo-keto reductase
           family 1 member C-like protein 1 - Homo sapiens (Human)
          Length = 302

 Score = 56.0 bits (129), Expect = 2e-06
 Identities = 34/111 (30%), Positives = 53/111 (47%), Gaps = 2/111 (1%)
 Frame = +3

Query: 252 LNNGVEMPAIGLDTFKMGHF--YTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLL 425
           LN+G  MP +G  T+   H       +    A+  G+R  D+A LY NE  +  A  + +
Sbjct: 13  LNDGPFMPVLGFGTYAPDHTPKSQAAEATKVAIDVGFRHIDSAYLYQNEEEVGQAIWEKI 72

Query: 426 PKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNP 578
               +KR +IF   KL    +    +   A   +L  LG DY+DL+++H P
Sbjct: 73  ADGTVKREEIFYTIKLW-ATFFRAELVHPALERSLKKLGPDYVDLFIIHVP 122


>UniRef50_Q9P734 Cluster: Related to 2, 5-diketo-D-gluconic acid
           reductase; n=5; Pezizomycotina|Rep: Related to 2,
           5-diketo-D-gluconic acid reductase - Neurospora crassa
          Length = 289

 Score = 55.6 bits (128), Expect = 3e-06
 Identities = 49/160 (30%), Positives = 72/160 (45%), Gaps = 4/160 (2%)
 Frame = +3

Query: 231 ILPQQFTLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFA 410
           +L ++  L+NG+ +P I L  + M    T  + V  AL AGYR FD+A  Y NE     A
Sbjct: 8   MLSRRVKLSNGLSIPQIQLGLYMMSGPETT-RAVRWALGAGYRGFDSAQWYYNEREAGQA 66

Query: 411 FKKLLPKYK----LKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNP 578
               L   +    L R D+   SKL   +    AV   +   ++   GL YIDL+L+H+P
Sbjct: 67  ILSFLSSPENTAGLTRKDVHFTSKLRDNSTNYDAV-RASISKSVKASGLGYIDLFLLHSP 125

Query: 579 GIYKLDFENRNSSRIRKQTWATLVDLYHDHKIRALGVSNY 698
                          R  +W  + D     +++  GVSNY
Sbjct: 126 ---------LGGREARLTSWKAVEDAVLAGEVKMAGVSNY 156


>UniRef50_Q5B5R6 Cluster: Putative uncharacterized protein; n=1;
           Emericella nidulans|Rep: Putative uncharacterized
           protein - Emericella nidulans (Aspergillus nidulans)
          Length = 682

 Score = 55.6 bits (128), Expect = 3e-06
 Identities = 41/110 (37%), Positives = 56/110 (50%)
 Frame = +3

Query: 240 QQFTLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKK 419
           + F LN G  +PA+GL T +      V + V  ALK GYR  DTA   G E  +  A K 
Sbjct: 412 RSFRLNTGALIPAVGLGTRRAQKPGLVYRAVRSALKTGYRHIDTAMSSGVEHEIGQAVK- 470

Query: 420 LLPKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLV 569
                 + R  +++ +KL   N     V E A   +LS LG+DY+DLYL+
Sbjct: 471 ---DSGVSRSQVWVTTKL--DNRWHTRVQE-ALDMSLSELGMDYVDLYLM 514


>UniRef50_UPI000038E317 Cluster: hypothetical protein Faci_03001732;
           n=1; Ferroplasma acidarmanus fer1|Rep: hypothetical
           protein Faci_03001732 - Ferroplasma acidarmanus fer1
          Length = 278

 Score = 55.2 bits (127), Expect = 4e-06
 Identities = 39/116 (33%), Positives = 58/116 (50%)
 Frame = +3

Query: 351 GYRMFDTAALYGNEVYLNFAFKKLLPKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTL 530
           G  + DTA LY  E  +  A K        KR ++F+ SK+ P +    ++ E+A + +L
Sbjct: 52  GINLIDTAELYRTEKLVGTAIKSY------KRDELFLASKVFPTHLSPKSL-EKALNRSL 104

Query: 531 SNLGLDYIDLYLVHNPGIYKLDFENRNSSRIRKQTWATLVDLYHDHKIRALGVSNY 698
            NL  DYIDLY +H P          N +   K+T  T+  +    KIR +GVSN+
Sbjct: 105 KNLDTDYIDLYQIHFP----------NPTVDIKKTLRTMEKMVDKGKIRHIGVSNF 150


>UniRef50_Q28P63 Cluster: Aldo/keto reductase; n=4;
           Rhodobacteraceae|Rep: Aldo/keto reductase - Jannaschia
           sp. (strain CCS1)
          Length = 276

 Score = 55.2 bits (127), Expect = 4e-06
 Identities = 39/148 (26%), Positives = 71/148 (47%)
 Frame = +3

Query: 255 NNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPKY 434
           ++G ++P +G   +++       +TV  A++ GYRM D A LY NE  L    +      
Sbjct: 10  HDGAQIPQVGFGIWQVPQDIAG-ETVRSAIEIGYRMIDGAYLYMNEAGLGEGLRAS---- 64

Query: 435 KLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLDFENRNS 614
            L R ++F+ +K+   N  G A    +   +L  +G++ +DL L+H P           S
Sbjct: 65  GLPRDEVFVTTKVWN-NEQGAAKARASVERSLKTIGVEQLDLVLIHWP---------VPS 114

Query: 615 SRIRKQTWATLVDLYHDHKIRALGVSNY 698
             +  +TW    D+  +  +R++G SN+
Sbjct: 115 QDLYLETWKAFQDMRDEGLMRSIGTSNF 142


  Database: uniref50
    Posted date:  Oct 5, 2007 11:19 AM
  Number of letters in database: 575,637,011
  Number of sequences in database:  1,657,284
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 1,211,982,708
Number of Sequences: 1657284
Number of extensions: 22438353
Number of successful extensions: 52476
Number of sequences better than 10.0: 449
Number of HSP's better than 10.0 without gapping: 43259
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 49670
length of database: 575,637,011
effective HSP length: 104
effective length of database: 403,279,475
effective search space used: 162521628425
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

- SilkBase 1999-2023 -