BLASTX 2.2.12 [Aug-07-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= 030731E7_B08_e634_04.seq (1525 letters) Database: uniref50 1,657,284 sequences; 575,637,011 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value UniRef50_Q5BLA6 Cluster: Zgc:110782; n=2; Danio rerio|Rep: Zgc:1... 138 3e-31 UniRef50_Q5XJM7 Cluster: Zgc:101765; n=5; Eumetazoa|Rep: Zgc:101... 136 1e-30 UniRef50_UPI00015B5BD7 Cluster: PREDICTED: similar to aldo-keto ... 130 7e-29 UniRef50_UPI0000DB6EE9 Cluster: PREDICTED: similar to C35D10.6; ... 124 6e-27 UniRef50_Q5TNP1 Cluster: ENSANGP00000029046; n=2; Culicidae|Rep:... 117 7e-25 UniRef50_Q6WGK4 Cluster: Aldose reductase; n=1; Pristionchus pac... 115 4e-24 UniRef50_Q1U9L6 Cluster: 2,5-didehydrogluconate reductase; n=3; ... 113 1e-23 UniRef50_P70883 Cluster: AkrI; n=1; Butyrivibrio fibrisolvens|Re... 110 1e-22 UniRef50_Q54NR2 Cluster: Aldo-keto reductase; n=3; Dictyostelium... 108 3e-22 UniRef50_Q21274 Cluster: Putative uncharacterized protein; n=1; ... 108 4e-22 UniRef50_Q18483 Cluster: Putative uncharacterized protein; n=2; ... 108 4e-22 UniRef50_Q17568 Cluster: Putative uncharacterized protein; n=1; ... 107 6e-22 UniRef50_P91997 Cluster: Putative uncharacterized protein; n=4; ... 106 1e-21 UniRef50_A6NPD6 Cluster: Putative uncharacterized protein; n=3; ... 104 5e-21 UniRef50_A6ESC0 Cluster: ARA1; n=1; unidentified eubacterium SCB... 103 9e-21 UniRef50_Q88SL1 Cluster: Oxidoreductase; n=51; Lactobacillales|R... 101 4e-20 UniRef50_Q5FLI5 Cluster: Aldehyde reductase; n=2; Bacteria|Rep: ... 99 2e-19 UniRef50_Q8F1G4 Cluster: Aldehyde reductase; n=8; Bacteria|Rep: ... 100 2e-19 UniRef50_Q838E0 Cluster: Oxidoreductase, aldo/keto reductase fam... 99 3e-19 UniRef50_Q23320 Cluster: Putative uncharacterized protein; n=4; ... 98 6e-19 UniRef50_Q9X0A2 Cluster: Oxidoreductase, aldo/keto reductase fam... 96 2e-18 UniRef50_Q05KR9 Cluster: Benzil reductase; n=5; Bacillales|Rep: ... 96 2e-18 UniRef50_Q5HR31 Cluster: Oxidoreductase, aldo/keto reductase fam... 94 8e-18 UniRef50_Q2V420 Cluster: Uncharacterized protein At2g37770.1; n=... 93 2e-17 UniRef50_Q0PGJ6 Cluster: Aldo-keto reductase; n=32; Magnoliophyt... 93 2e-17 UniRef50_P45376 Cluster: Aldose reductase; n=21; Bilateria|Rep: ... 93 2e-17 UniRef50_P15121 Cluster: Aldose reductase; n=72; Eumetazoa|Rep: ... 92 4e-17 UniRef50_Q03TW0 Cluster: Aldo/keto reductase of diketogulonate r... 91 7e-17 UniRef50_Q8CI22 Cluster: 2310005E10Rik protein; n=30; Tetrapoda|... 91 9e-17 UniRef50_Q41E86 Cluster: 2,5-didehydrogluconate reductase; n=2; ... 91 9e-17 UniRef50_Q9VHX4 Cluster: CG2767-PA; n=4; Endopterygota|Rep: CG27... 91 9e-17 UniRef50_Q03PG5 Cluster: Aldo/keto reductase of diketogulonate r... 90 2e-16 UniRef50_Q16K66 Cluster: Aldo-keto reductase; n=2; Aedes aegypti... 90 2e-16 UniRef50_Q5FK98 Cluster: Oxidoreductase; n=8; Lactobacillales|Re... 89 2e-16 UniRef50_A2UAH0 Cluster: Aldo/keto reductase; n=1; Bacillus coag... 89 2e-16 UniRef50_A6LZ55 Cluster: 2,5-didehydrogluconate reductase; n=1; ... 89 4e-16 UniRef50_Q09632 Cluster: Probable oxidoreductase ZK1290.5; n=2; ... 89 4e-16 UniRef50_Q03XK0 Cluster: Aldo/keto reductase of diketogulonate r... 88 5e-16 UniRef50_Q7NB44 Cluster: ARA1; n=3; Firmicutes|Rep: ARA1 - Mycop... 88 7e-16 UniRef50_Q61U89 Cluster: Putative uncharacterized protein CBG054... 88 7e-16 UniRef50_A0JRJ6 Cluster: Aldo/keto reductase; n=2; Micrococcinea... 87 9e-16 UniRef50_Q24C22 Cluster: Oxidoreductase, aldo/keto reductase fam... 87 9e-16 UniRef50_P38715 Cluster: NADPH-dependent aldose reductase GRE3; ... 87 1e-15 UniRef50_Q2LZ66 Cluster: GA19341-PA; n=2; Endopterygota|Rep: GA1... 86 2e-15 UniRef50_Q22352 Cluster: Putative uncharacterized protein T08H10... 86 2e-15 UniRef50_UPI0000588153 Cluster: PREDICTED: hypothetical protein;... 86 3e-15 UniRef50_UPI000065D0BD Cluster: Homolog of Homo sapiens "AKR1B1 ... 86 3e-15 UniRef50_P22045 Cluster: Probable reductase; n=101; cellular org... 86 3e-15 UniRef50_Q02198 Cluster: Morphine 6-dehydrogenase; n=5; Bacteria... 86 3e-15 UniRef50_Q55FL3 Cluster: Aldo-keto reductase; n=2; Dictyostelium... 85 5e-15 UniRef50_Q7VG53 Cluster: Aldo-keto reductase; n=28; Bacteria|Rep... 85 6e-15 UniRef50_P38115 Cluster: D-arabinose dehydrogenase [NAD(P)+] hea... 85 6e-15 UniRef50_Q8WRT0 Cluster: 3-dehydrecdysone 3b-reductase; n=1; Tri... 84 8e-15 UniRef50_Q54B70 Cluster: Aldehyde reductase; n=2; Dictyostelium ... 84 8e-15 UniRef50_Q9VTL0 Cluster: CG6083-PA; n=4; Diptera|Rep: CG6083-PA ... 84 1e-14 UniRef50_A5E082 Cluster: GCY protein; n=4; Saccharomycetales|Rep... 84 1e-14 UniRef50_A3LTU8 Cluster: D-arabinose dehydrogenase; n=5; Sacchar... 84 1e-14 UniRef50_UPI00006CA3CB Cluster: oxidoreductase, aldo/keto reduct... 83 1e-14 UniRef50_Q568D7 Cluster: Zgc:110366; n=7; Euteleostomi|Rep: Zgc:... 83 1e-14 UniRef50_A3JU52 Cluster: 2,5-diketo-D-gluconic acid reductase A;... 83 1e-14 UniRef50_Q2UGR1 Cluster: Aldo/keto reductase family proteins; n=... 83 1e-14 UniRef50_A7PNI3 Cluster: Chromosome chr1 scaffold_22, whole geno... 83 2e-14 UniRef50_Q0IBY6 Cluster: Alcohol dehydrogenase; n=2; Chroococcal... 82 3e-14 UniRef50_Q6TY50 Cluster: Reductase 2; n=10; Magnoliophyta|Rep: R... 82 3e-14 UniRef50_Q7PM68 Cluster: ENSANGP00000014386; n=1; Anopheles gamb... 82 3e-14 UniRef50_Q8SSK6 Cluster: ALDOSE REDUCTASE; n=1; Encephalitozoon ... 82 4e-14 UniRef50_Q6NII7 Cluster: Putative oxidoreductase; n=2; Corynebac... 81 6e-14 UniRef50_Q1RFP0 Cluster: 2,5-diketo-D-gluconic acid reductase A;... 81 6e-14 UniRef50_Q9ZBW7 Cluster: Putative oxidoreductase; n=2; Actinomyc... 81 8e-14 UniRef50_Q927E1 Cluster: Lin2848 protein; n=13; Listeria|Rep: Li... 81 8e-14 UniRef50_A5KSS3 Cluster: Aldehyde reductase; n=1; candidate divi... 81 8e-14 UniRef50_Q7ZA52 Cluster: Aldose reductase; n=6; Pezizomycotina|R... 81 8e-14 UniRef50_A6RKL9 Cluster: Putative uncharacterized protein; n=3; ... 81 8e-14 UniRef50_A7CWF9 Cluster: Aldehyde reductase; n=2; Bacteria|Rep: ... 81 1e-13 UniRef50_A4FEB9 Cluster: 2,5-diketo-D-gluconic acid reductase; n... 81 1e-13 UniRef50_A1D4E3 Cluster: D-xylose reductase (Xyl1), putative; n=... 81 1e-13 UniRef50_Q235V6 Cluster: Oxidoreductase, aldo/keto reductase fam... 80 1e-13 UniRef50_Q4P4P1 Cluster: Putative uncharacterized protein; n=1; ... 80 1e-13 UniRef50_Q890A0 Cluster: Oxidoreductase; n=6; Lactobacillales|Re... 80 2e-13 UniRef50_Q7JVH6 Cluster: LD24696p; n=2; Sophophora|Rep: LD24696p... 80 2e-13 UniRef50_Q4PE96 Cluster: Putative uncharacterized protein; n=1; ... 80 2e-13 UniRef50_Q8EVT8 Cluster: Oxidoreductase-aldo/keto reductase fami... 79 2e-13 UniRef50_UPI00015B56A2 Cluster: PREDICTED: similar to GA10458-PA... 79 3e-13 UniRef50_UPI00006CCCD7 Cluster: oxidoreductase, aldo/keto reduct... 79 3e-13 UniRef50_UPI0000498F1F Cluster: oxidoreductase, aldo/keto reduct... 79 3e-13 UniRef50_Q2S340 Cluster: Aldehyde reductase; n=10; Bacteria|Rep:... 79 3e-13 UniRef50_Q1VRG6 Cluster: YvgN; n=1; Psychroflexus torquis ATCC 7... 79 3e-13 UniRef50_A0JX62 Cluster: 2,5-didehydrogluconate reductase; n=9; ... 79 3e-13 UniRef50_A2R6Z3 Cluster: Catalytic activity: an alcohol + NADP(+... 79 3e-13 UniRef50_P47137 Cluster: Probable oxidoreductase YJR096W; n=8; S... 79 3e-13 UniRef50_UPI00006CD296 Cluster: oxidoreductase, aldo/keto reduct... 79 4e-13 UniRef50_A4RQH8 Cluster: Predicted protein; n=2; Ostreococcus|Re... 79 4e-13 UniRef50_Q968S3 Cluster: Aldoketoreductase-like protein; n=1; Or... 79 4e-13 UniRef50_Q9C1X5 Cluster: Xylose and arabinose reductase; n=1; Sc... 79 4e-13 UniRef50_Q7VHE1 Cluster: Putative uncharacterized protein; n=1; ... 78 5e-13 UniRef50_Q4Q5N9 Cluster: Prostaglandin f synthase, putative; n=7... 78 7e-13 UniRef50_Q17G72 Cluster: Aldo-keto reductase; n=9; Endopterygota... 78 7e-13 UniRef50_UPI0000519CC2 Cluster: PREDICTED: similar to CG2767-PA;... 77 9e-13 UniRef50_Q8Y463 Cluster: Lmo2592 protein; n=40; Bacteria|Rep: Lm... 77 9e-13 UniRef50_Q4PDR0 Cluster: Putative uncharacterized protein; n=1; ... 77 1e-12 UniRef50_Q88TV9 Cluster: Oxidoreductase; n=4; Lactobacillus|Rep:... 77 2e-12 UniRef50_A6VNW9 Cluster: Aldo/keto reductase precursor; n=1; Act... 76 2e-12 UniRef50_Q10494 Cluster: Probable oxidoreductase C26F1.07; n=2; ... 76 2e-12 UniRef50_A7ALH6 Cluster: Putative uncharacterized protein; n=1; ... 76 3e-12 UniRef50_A2QBD7 Cluster: Catalytic activity: an alcohol + NADP(+... 76 3e-12 UniRef50_UPI00015B56A3 Cluster: PREDICTED: similar to aldo-keto ... 75 4e-12 UniRef50_Q1IN88 Cluster: Aldehyde reductase; n=5; Bacteria|Rep: ... 75 4e-12 UniRef50_Q9Y020 Cluster: 3-dehydroecdysone 3beta-reductase precu... 75 4e-12 UniRef50_A2QVE5 Cluster: Similarity: shows similarity to several... 75 4e-12 UniRef50_P14550 Cluster: Alcohol dehydrogenase [NADP+]; n=44; Bi... 75 4e-12 UniRef50_Q96UH3 Cluster: Aldehyde reductase; n=13; Pezizomycotin... 75 5e-12 UniRef50_Q5FKI1 Cluster: Reductase-dehydrogenase; n=1; Lactobaci... 75 7e-12 UniRef50_Q11BF8 Cluster: Aldo/keto reductase; n=12; Bacteria|Rep... 75 7e-12 UniRef50_Q03X85 Cluster: Aldo/keto reductase of diketogulonate r... 75 7e-12 UniRef50_A7SIT3 Cluster: Predicted protein; n=1; Nematostella ve... 75 7e-12 UniRef50_Q6C2L0 Cluster: Yarrowia lipolytica chromosome F of str... 74 9e-12 UniRef50_UPI00015B4B22 Cluster: PREDICTED: similar to GA15457-PA... 74 1e-11 UniRef50_Q8EUH6 Cluster: Oxidoreductase; n=1; Mycoplasma penetra... 74 1e-11 UniRef50_Q17DN0 Cluster: Aldo-keto reductase; n=5; Culicidae|Rep... 74 1e-11 UniRef50_Q929C8 Cluster: Lin2349 protein; n=12; Listeria|Rep: Li... 73 2e-11 UniRef50_Q3CZS2 Cluster: Oxidoreductase, aldo/keto reductase fam... 73 2e-11 UniRef50_Q03U37 Cluster: Aldo/keto reductase of diketogulonate r... 73 2e-11 UniRef50_Q927P9 Cluster: Lin2739 protein; n=12; Bacteria|Rep: Li... 73 2e-11 UniRef50_Q043M4 Cluster: Aldo/keto reductase of diketogulonate r... 73 2e-11 UniRef50_P27800 Cluster: Aldehyde reductase 1; n=18; root|Rep: A... 73 2e-11 UniRef50_Q14LU6 Cluster: Putative aldo/keto reductase oxidoreduc... 73 3e-11 UniRef50_Q41399 Cluster: Chalcone reductase; n=4; eudicotyledons... 73 3e-11 UniRef50_Q6CFG7 Cluster: Yarrowia lipolytica chromosome B of str... 73 3e-11 UniRef50_A4YQ04 Cluster: 2,5-diketo-D-gluconate reductase B; n=1... 72 3e-11 UniRef50_A1UEC5 Cluster: 2,5-didehydrogluconate reductase; n=20;... 72 3e-11 UniRef50_Q5KI95 Cluster: Aldo-keto reductase, putative; n=14; Di... 72 3e-11 UniRef50_UPI00015B40FA Cluster: PREDICTED: similar to CG2767-PA;... 72 5e-11 UniRef50_Q1YPE5 Cluster: Aldehyde reductase; n=7; Bacteria|Rep: ... 72 5e-11 UniRef50_A0JRJ3 Cluster: 2,5-didehydrogluconate reductase; n=3; ... 72 5e-11 UniRef50_A7RRF6 Cluster: Predicted protein; n=2; Nematostella ve... 71 6e-11 UniRef50_P28475 Cluster: NADP-dependent D-sorbitol-6-phosphate d... 71 8e-11 UniRef50_P23901 Cluster: Aldose reductase; n=9; Poaceae|Rep: Ald... 71 8e-11 UniRef50_Q5KCN9 Cluster: Putative uncharacterized protein; n=1; ... 70 1e-10 UniRef50_A2QL02 Cluster: Putative frameshift; n=1; Aspergillus n... 70 1e-10 UniRef50_UPI0000E4A7CE Cluster: PREDICTED: similar to LOC553452 ... 70 2e-10 UniRef50_UPI000023D0F1 Cluster: hypothetical protein FG03517.1; ... 70 2e-10 UniRef50_A3U9Y0 Cluster: Aldehyde reductase; n=5; Bacteroidetes|... 70 2e-10 UniRef50_Q9NAI5 Cluster: Putative uncharacterized protein; n=3; ... 70 2e-10 UniRef50_Q2BBN7 Cluster: YvgN; n=1; Bacillus sp. NRRL B-14911|Re... 69 3e-10 UniRef50_Q75E75 Cluster: ABL209Cp; n=1; Eremothecium gossypii|Re... 69 3e-10 UniRef50_A7EW94 Cluster: Putative uncharacterized protein; n=1; ... 69 4e-10 UniRef50_P06632 Cluster: 2,5-diketo-D-gluconic acid reductase A;... 69 4e-10 UniRef50_UPI0000D56CE5 Cluster: PREDICTED: similar to CG6084-PA,... 68 6e-10 UniRef50_Q0VGY1 Cluster: 3-alpha-hydroxysteroid dehydrogenase; n... 68 6e-10 UniRef50_Q9FJK0 Cluster: Aldose reductase-like protein; n=3; cor... 68 6e-10 UniRef50_Q8G7K9 Cluster: Dehydrogenase or reductase protein; n=4... 68 8e-10 UniRef50_Q7ZWA4 Cluster: Zgc:56622; n=6; cellular organisms|Rep:... 67 1e-09 UniRef50_Q7QK25 Cluster: ENSANGP00000019775; n=2; Anopheles gamb... 67 1e-09 UniRef50_Q4JX70 Cluster: Putative oxidoreductase; n=1; Corynebac... 67 1e-09 UniRef50_Q01HB5 Cluster: OSIGBa0136O08-OSIGBa0153H12.9 protein; ... 67 1e-09 UniRef50_A7SGW6 Cluster: Predicted protein; n=1; Nematostella ve... 67 1e-09 UniRef50_Q7G765 Cluster: Probable NAD(P)H-dependent oxidoreducta... 67 1e-09 UniRef50_Q5FK99 Cluster: Oxidoreductase aldo-keto reductase fami... 66 2e-09 UniRef50_Q9P6D3 Cluster: Related to aldo-keto reductase YPR1; n=... 66 2e-09 UniRef50_Q0CLQ2 Cluster: Putative uncharacterized protein; n=1; ... 66 2e-09 UniRef50_Q7N0E4 Cluster: 2,5-diketo-D-gluconic acid reductase A;... 66 2e-09 UniRef50_Q7PCV3 Cluster: ENSANGP00000031808; n=9; Endopterygota|... 66 2e-09 UniRef50_Q68ST9 Cluster: Reductase AKOR2; n=2; Pleurotus djamor|... 66 2e-09 UniRef50_Q96JD6-2 Cluster: Isoform 2 of Q96JD6 ; n=4; Catarrhini... 66 3e-09 UniRef50_Q83N50 Cluster: 2,5-diketo-D-gluconic acid reductase; n... 66 3e-09 UniRef50_Q572D2 Cluster: Aldo-keto reductase, putative; n=1; Phy... 66 3e-09 UniRef50_Q68A33 Cluster: Aldo-keto reductase 1a; n=1; Ciona inte... 66 3e-09 UniRef50_Q96JD6 Cluster: Aldo-keto reductase family 1 member C-l... 66 3e-09 UniRef50_A5VK30 Cluster: 2,5-didehydrogluconate reductase; n=2; ... 65 4e-09 UniRef50_Q7XY49 Cluster: Mannose 6-phosphate reductase; n=1; Gri... 65 4e-09 UniRef50_Q7QVQ9 Cluster: GLP_302_44328_45269; n=1; Giardia lambl... 65 4e-09 UniRef50_Q8J0K1 Cluster: 4-dihydromethyltrisporate dehydrogenase... 65 4e-09 UniRef50_A5DRJ6 Cluster: Putative uncharacterized protein; n=4; ... 65 4e-09 UniRef50_P26690 Cluster: NAD(P)H-dependent 6'-deoxychalcone synt... 65 4e-09 UniRef50_Q4WUF7 Cluster: Aldo-keto reductase, putative; n=3; Pez... 65 5e-09 UniRef50_Q5UX52 Cluster: Oxidoreductase aldo/keto reductase fami... 65 5e-09 UniRef50_A7CUW0 Cluster: 2,5-didehydrogluconate reductase; n=6; ... 64 7e-09 UniRef50_A5ZYE6 Cluster: Putative uncharacterized protein; n=1; ... 64 7e-09 UniRef50_A7RUA2 Cluster: Predicted protein; n=1; Nematostella ve... 64 7e-09 UniRef50_A2G4I3 Cluster: Oxidoreductase, aldo/keto reductase fam... 64 7e-09 UniRef50_Q9HGY0 Cluster: Glycerol dehydrogenase; n=8; Saccharomy... 64 7e-09 UniRef50_Q6CGE9 Cluster: Similar to sp|P47137 Saccharomyces cere... 64 7e-09 UniRef50_Q4DJ59 Cluster: Aldo/keto reductase, putative; n=2; Try... 64 9e-09 UniRef50_Q76L37 Cluster: Conjugated polyketone reductase C1; n=3... 64 9e-09 UniRef50_Q7G764 Cluster: Probable NAD(P)H-dependent oxidoreducta... 64 9e-09 UniRef50_P14065 Cluster: Protein GCY; n=13; Saccharomycetales|Re... 64 9e-09 UniRef50_Q6U5V3 Cluster: Putative uncharacterized protein; n=1; ... 64 1e-08 UniRef50_A7BA05 Cluster: Putative uncharacterized protein; n=1; ... 64 1e-08 UniRef50_Q4FY75 Cluster: Aldo-keto reductase-like protein; n=5; ... 64 1e-08 UniRef50_Q2U219 Cluster: Aldo/keto reductase family proteins; n=... 64 1e-08 UniRef50_O14088 Cluster: Xylose and arabinose reductase; n=1; Sc... 64 1e-08 UniRef50_Q9X265 Cluster: Oxidoreductase, aldo/keto reductase fam... 63 2e-08 UniRef50_Q6RZX1 Cluster: Gld1; n=22; Pezizomycotina|Rep: Gld1 - ... 63 2e-08 UniRef50_A3VHZ9 Cluster: Oxidoreductase; n=1; Rhodobacterales ba... 63 2e-08 UniRef50_Q00XM4 Cluster: Aldo/keto reductase family proteins; n=... 63 2e-08 UniRef50_Q8ZI40 Cluster: 2,5-diketo-D-gluconic acid reductase A;... 63 2e-08 UniRef50_UPI000155CAC7 Cluster: PREDICTED: hypothetical protein;... 62 3e-08 UniRef50_Q4Q973 Cluster: Aldo/keto reductase, putative; n=3; Lei... 62 3e-08 UniRef50_A2EHN6 Cluster: Oxidoreductase, aldo/keto reductase fam... 62 3e-08 UniRef50_Q4PAT5 Cluster: Putative uncharacterized protein; n=1; ... 62 3e-08 UniRef50_Q8EVS8 Cluster: Oxidoreductase; n=1; Mycoplasma penetra... 62 4e-08 UniRef50_A5PDA8 Cluster: Putative oxidoreductase protein; n=1; E... 62 4e-08 UniRef50_A7D6Q0 Cluster: Aldo/keto reductase; n=1; Halorubrum la... 62 4e-08 UniRef50_Q8VC28 Cluster: Aldo-keto reductase family 1 member C13... 62 4e-08 UniRef50_UPI0000E45E29 Cluster: PREDICTED: similar to aldose red... 62 5e-08 UniRef50_Q5K8C5 Cluster: Aldo-keto reductase, putative; n=1; Fil... 62 5e-08 UniRef50_Q9A2X8 Cluster: Oxidoreductase, aldo/keto reductase fam... 61 7e-08 UniRef50_Q7WSY4 Cluster: Putative aldo-keto reductase; n=1; Prop... 61 7e-08 UniRef50_Q9ZUJ6 Cluster: T2K10.1 protein; n=16; core eudicotyled... 61 7e-08 UniRef50_Q7R2T6 Cluster: GLP_291_56367_57278; n=1; Giardia lambl... 61 7e-08 UniRef50_Q5BKE9 Cluster: LOC594893 protein; n=5; Xenopus tropica... 61 9e-08 UniRef50_Q5KD52 Cluster: Oxidoreductase, putative; n=1; Filobasi... 61 9e-08 UniRef50_A3T261 Cluster: Putative uncharacterized protein; n=1; ... 60 2e-07 UniRef50_A1CAM7 Cluster: Aldo-keto reductase, putative; n=9; Dik... 60 2e-07 UniRef50_Q11B35 Cluster: Aldo/keto reductase; n=1; Mesorhizobium... 60 2e-07 UniRef50_A5AD50 Cluster: Putative uncharacterized protein; n=3; ... 60 2e-07 UniRef50_A3C1Z7 Cluster: Putative uncharacterized protein; n=2; ... 60 2e-07 UniRef50_UPI0000D9A956 Cluster: PREDICTED: similar to aldo-keto ... 59 3e-07 UniRef50_Q6F7K7 Cluster: 2,5-diketo-D-gluconate reductase; n=20;... 59 3e-07 UniRef50_Q9U2J5 Cluster: Putative uncharacterized protein; n=2; ... 59 3e-07 UniRef50_A6RMS0 Cluster: Putative uncharacterized protein; n=1; ... 59 3e-07 UniRef50_Q5UYI9 Cluster: Oxidoreductase; n=1; Haloarcula marismo... 59 3e-07 UniRef50_P51857 Cluster: 3-oxo-5-beta-steroid 4-dehydrogenase (E... 59 3e-07 UniRef50_Q8ET73 Cluster: 2,5-diketo-D-gluconate reductase; n=12;... 58 5e-07 UniRef50_Q0GU15 Cluster: ORF28; n=3; Bacteria|Rep: ORF28 - Lacto... 58 5e-07 UniRef50_Q8K023 Cluster: Aldo-keto reductase family 1 member C18... 58 5e-07 UniRef50_A3UJS6 Cluster: Oxidoreductase; n=3; Alphaproteobacteri... 58 6e-07 UniRef50_Q01J82 Cluster: OSIGBa0152K17.5 protein; n=28; Magnolio... 58 6e-07 UniRef50_P91021 Cluster: Putative uncharacterized protein; n=1; ... 58 6e-07 UniRef50_Q4V008 Cluster: Oxidoreductase; n=4; Proteobacteria|Rep... 58 8e-07 UniRef50_Q4Q5X1 Cluster: Aldehyde reductase, putative; n=75; cel... 58 8e-07 UniRef50_UPI0000499B0E Cluster: oxidoreductase, aldo/keto reduct... 57 1e-06 UniRef50_A6WDZ5 Cluster: Aldo/keto reductase; n=5; Bacteria|Rep:... 57 1e-06 UniRef50_UPI00015B4912 Cluster: PREDICTED: similar to aldo-keto ... 57 1e-06 UniRef50_Q11DV1 Cluster: Aldo/keto reductase; n=10; Alphaproteob... 57 1e-06 UniRef50_Q0SFM4 Cluster: Probable 2,5-didehydrogluconate reducta... 57 1e-06 UniRef50_A2EYY6 Cluster: Oxidoreductase, aldo/keto reductase fam... 57 1e-06 UniRef50_A6SJ74 Cluster: Putative uncharacterized protein; n=1; ... 57 1e-06 UniRef50_Q6CEJ0 Cluster: Yarrowia lipolytica chromosome B of str... 56 2e-06 UniRef50_Q59Z55 Cluster: Potential aldo/keto reductase; n=6; Sac... 56 2e-06 UniRef50_Q9HM42 Cluster: Alcohol dehydrogenase related protein; ... 56 2e-06 UniRef50_Q5NLW3 Cluster: Putative oxidoreductase; n=1; Zymomonas... 56 2e-06 UniRef50_A7P424 Cluster: Chromosome chr1 scaffold_5, whole genom... 56 2e-06 UniRef50_Q76L36 Cluster: Conjugated polyketone reductase C2; n=1... 56 2e-06 UniRef50_A7D7K7 Cluster: Aldo/keto reductase; n=1; Halorubrum la... 56 2e-06 UniRef50_Q5T2L2 Cluster: Aldo-keto reductase family 1 member C-l... 56 2e-06 UniRef50_Q9P734 Cluster: Related to 2, 5-diketo-D-gluconic acid ... 56 3e-06 UniRef50_Q5B5R6 Cluster: Putative uncharacterized protein; n=1; ... 56 3e-06 UniRef50_UPI000038E317 Cluster: hypothetical protein Faci_030017... 55 4e-06 UniRef50_Q28P63 Cluster: Aldo/keto reductase; n=4; Rhodobacterac... 55 4e-06 UniRef50_A6W8E7 Cluster: 2,5-didehydrogluconate reductase; n=3; ... 55 4e-06 UniRef50_A0AWM8 Cluster: Aldo/keto reductase; n=4; Actinomycetal... 55 4e-06 UniRef50_P15339 Cluster: 2,5-diketo-D-gluconic acid reductase B;... 55 4e-06 UniRef50_Q14LA8 Cluster: Putative aldo/keto reductase oxidoreduc... 55 6e-06 UniRef50_A1RB46 Cluster: 2,5-diketo-D-gluconate reductase; n=1; ... 55 6e-06 UniRef50_O13848 Cluster: NADH/NADPH dependent indole-3-acetaldeh... 55 6e-06 UniRef50_A7TLC4 Cluster: Putative uncharacterized protein; n=1; ... 55 6e-06 UniRef50_Q89JN4 Cluster: Oxidoreductase; n=8; Rhizobiales|Rep: O... 54 7e-06 UniRef50_A7LSN6 Cluster: Putative uncharacterized protein; n=3; ... 54 7e-06 UniRef50_A7BES9 Cluster: Putative uncharacterized protein; n=1; ... 54 7e-06 UniRef50_Q7PLK6 Cluster: CG40064-PA; n=1; Drosophila melanogaste... 54 7e-06 UniRef50_Q64W37 Cluster: 2,5-diketo-D-gluconic acid reductase; n... 54 1e-05 UniRef50_Q6XUT6 Cluster: Oxido-reductase/dehydratase; n=3; Bacte... 54 1e-05 UniRef50_A2RMU6 Cluster: Oxidoreductase, aldo/keto reductase fam... 53 2e-05 UniRef50_A2FPE2 Cluster: Oxidoreductase, aldo/keto reductase fam... 53 2e-05 UniRef50_Q4P1G1 Cluster: Putative uncharacterized protein; n=1; ... 53 2e-05 UniRef50_Q5FT75 Cluster: Putative 2,5-diketo-D-gluconic acid red... 53 2e-05 UniRef50_Q8ZH36 Cluster: 2,5-diketo-D-gluconic acid reductase B;... 53 2e-05 UniRef50_P76234 Cluster: Uncharacterized protein yeaE; n=39; Bac... 52 3e-05 UniRef50_Q15NA5 Cluster: Aldo/keto reductase; n=2; Gammaproteoba... 52 4e-05 UniRef50_Q03UP2 Cluster: Aryl-alcohol dehydrogenase family enzym... 52 4e-05 UniRef50_A3LWP0 Cluster: Aldo/keto reductase; n=7; Saccharomycet... 52 4e-05 UniRef50_Q1M4Z6 Cluster: Putative aldo-keto reductase/oxidase; n... 51 7e-05 UniRef50_A2QB88 Cluster: Contig An01c0460, complete genome. prec... 51 7e-05 UniRef50_UPI00005F9591 Cluster: COG0656: Aldo/keto reductases, r... 51 9e-05 UniRef50_A3H9Y8 Cluster: Aldo/keto reductase; n=2; Caldivirga ma... 51 9e-05 UniRef50_Q8PN61 Cluster: Oxidoreductase; n=5; Proteobacteria|Rep... 50 1e-04 UniRef50_Q1DLF1 Cluster: Putative uncharacterized protein; n=1; ... 50 1e-04 UniRef50_Q5V663 Cluster: Aldehyde reductase; n=6; Halobacteriace... 50 1e-04 UniRef50_Q5V398 Cluster: Oxidoreductase aldo/keto reductase fami... 50 1e-04 UniRef50_Q64UK5 Cluster: Aldo/keto reductase family oxidoreducta... 50 2e-04 UniRef50_A2WWZ1 Cluster: Putative uncharacterized protein; n=1; ... 50 2e-04 UniRef50_Q17DN1 Cluster: Aldo-keto reductase; n=1; Aedes aegypti... 50 2e-04 UniRef50_Q4PHK0 Cluster: Putative uncharacterized protein; n=1; ... 50 2e-04 UniRef50_Q2CAL9 Cluster: 2,5-didehydrogluconate reductase; n=2; ... 49 3e-04 UniRef50_Q21EY6 Cluster: Aldo/keto reductase; n=1; Saccharophagu... 49 3e-04 UniRef50_A0JTR5 Cluster: Aldo/keto reductase; n=2; Actinomycetal... 49 4e-04 UniRef50_Q013C5 Cluster: Glycerol dehydrogenase, putative; n=2; ... 49 4e-04 UniRef50_Q0CK00 Cluster: Predicted protein; n=1; Aspergillus ter... 49 4e-04 UniRef50_Q97UV9 Cluster: Oxidoreductase; n=1; Sulfolobus solfata... 49 4e-04 UniRef50_Q39MY8 Cluster: Aldo/keto reductase; n=10; Bacteria|Rep... 48 5e-04 UniRef50_Q2FGN2 Cluster: Oxidoreductase, aldo/keto reductase fam... 48 5e-04 UniRef50_Q4WP69 Cluster: Aldehyde reductase, putative; n=1; Aspe... 48 5e-04 UniRef50_Q5V6N9 Cluster: Alcohol dehydrogenase; n=2; Halobacteri... 48 5e-04 UniRef50_Q4HND9 Cluster: Oxidoreductase, aldo/keto reductase fam... 48 6e-04 UniRef50_A5BF24 Cluster: Putative uncharacterized protein; n=1; ... 48 6e-04 UniRef50_Q9USV2 Cluster: Xylose and arabinose reductase; n=2; Sc... 48 6e-04 UniRef50_A7D6I8 Cluster: Aldo/keto reductase; n=1; Halorubrum la... 48 6e-04 UniRef50_Q03BE0 Cluster: Aldo/keto reductase family enzyme; n=5;... 48 9e-04 UniRef50_Q4WI64 Cluster: Aldehyde reductase, putative; n=22; Pez... 48 9e-04 UniRef50_A5BYJ4 Cluster: Putative uncharacterized protein; n=1; ... 47 0.001 UniRef50_Q5B034 Cluster: Putative uncharacterized protein; n=1; ... 47 0.001 UniRef50_Q1Q8W8 Cluster: Aldo/keto reductase; n=1; Psychrobacter... 46 0.003 UniRef50_Q2H7A8 Cluster: Putative uncharacterized protein; n=1; ... 46 0.003 UniRef50_Q8YXI8 Cluster: All1225 protein; n=9; Cyanobacteria|Rep... 46 0.003 UniRef50_Q03I00 Cluster: Aryl-alcohol dehydrogenase related enzy... 46 0.003 UniRef50_A6PR52 Cluster: Aldo/keto reductase; n=1; Victivallis v... 46 0.003 UniRef50_Q98IA6 Cluster: Aryl-alcohol dehydrogenase; n=1; Mesorh... 45 0.005 UniRef50_A0VAL7 Cluster: Aldo/keto reductase; n=2; Proteobacteri... 45 0.005 UniRef50_A6SI80 Cluster: Putative uncharacterized protein; n=1; ... 45 0.005 UniRef50_Q6L139 Cluster: 2,5-diketo-D-gluconic acid reductase; n... 45 0.005 UniRef50_Q07551 Cluster: NADPH-dependent alpha-keto amide reduct... 45 0.005 UniRef50_Q096Q3 Cluster: Oxidoreductase, aldo reductase; n=1; St... 45 0.006 UniRef50_Q3E9M9 Cluster: Uncharacterized protein At5g01670.2; n=... 45 0.006 UniRef50_Q55ML8 Cluster: Putative uncharacterized protein; n=2; ... 45 0.006 UniRef50_A1CCJ1 Cluster: Aldo/keto reductase; n=2; Trichocomacea... 45 0.006 UniRef50_A7D761 Cluster: Aldo/keto reductase; n=2; Halobacteriac... 45 0.006 UniRef50_Q89RG2 Cluster: Aldo/keto reductase; n=11; Bacteria|Rep... 44 0.008 UniRef50_A3VRL4 Cluster: Putative uncharacterized protein; n=1; ... 44 0.008 UniRef50_Q9V2P1 Cluster: Myo-inositol degradation; n=5; Archaea|... 44 0.008 UniRef50_UPI000023DF27 Cluster: hypothetical protein FG07276.1; ... 44 0.011 UniRef50_Q97L01 Cluster: Fe-S oxidoreductase; n=4; Clostridium|R... 44 0.011 UniRef50_Q97KZ9 Cluster: Fe-S oxidoreductase; n=6; cellular orga... 44 0.011 UniRef50_Q660Z5 Cluster: Aldose reductase, putative; n=3; Borrel... 44 0.011 UniRef50_Q5FHT2 Cluster: Aldehyde reductase; n=4; Lactobacillus|... 44 0.014 UniRef50_A5UXT4 Cluster: Aldo/keto reductase; n=2; Roseiflexus|R... 44 0.014 UniRef50_Q1PV10 Cluster: Putative uncharacterized protein; n=1; ... 43 0.018 UniRef50_Q16CS5 Cluster: 2,5-diketo-D-gluconic acid reductase B,... 43 0.018 UniRef50_Q0B0F0 Cluster: Oxidoreductase; n=1; Syntrophomonas wol... 43 0.018 UniRef50_A1S0T5 Cluster: Aldo/keto reductase; n=2; Thermoprotei|... 43 0.018 UniRef50_A6FYX9 Cluster: Oxidoreductase; n=1; Plesiocystis pacif... 43 0.024 UniRef50_Q31SB1 Cluster: Putative uncharacterized protein; n=2; ... 42 0.032 UniRef50_Q97V56 Cluster: Dehydrogenase; n=8; Thermoprotei|Rep: D... 42 0.032 UniRef50_A7PNT1 Cluster: Chromosome chr8 scaffold_23, whole geno... 42 0.043 UniRef50_Q18903 Cluster: Putative uncharacterized protein C56G3.... 42 0.043 UniRef50_Q5V0P8 Cluster: Oxidoreductase; n=2; Halobacteriaceae|R... 42 0.043 UniRef50_Q0W0V6 Cluster: Predicted aldo/keto reductase; n=2; Eur... 42 0.043 UniRef50_P82125 Cluster: 1,5-anhydro-D-fructose reductase; n=1; ... 42 0.043 UniRef50_Q49V75 Cluster: Putative oxidoreductase; n=1; Staphyloc... 42 0.056 UniRef50_A6W292 Cluster: Aldo/keto reductase; n=9; Bacteria|Rep:... 42 0.056 UniRef50_A6DRY4 Cluster: Aldo/keto reductase; n=1; Lentisphaera ... 42 0.056 UniRef50_A3DNU7 Cluster: Aldo/keto reductase; n=3; Desulfurococc... 42 0.056 UniRef50_A6S357 Cluster: Putative uncharacterized protein; n=2; ... 41 0.075 UniRef50_Q2J7H2 Cluster: Aldo/keto reductase; n=16; Bacteria|Rep... 41 0.099 UniRef50_Q4WF80 Cluster: Glycerol dehydrogenase (GCY1), putative... 41 0.099 UniRef50_Q97U17 Cluster: Oxidoreductase, aldo/keto reductase fam... 41 0.099 UniRef50_Q7D001 Cluster: AGR_C_2023p; n=14; Proteobacteria|Rep: ... 40 0.13 UniRef50_Q097V7 Cluster: MocA; n=1; Stigmatella aurantiaca DW4/3... 40 0.13 UniRef50_A6SUJ2 Cluster: Uncharacterized conserved protein; n=2;... 40 0.13 UniRef50_A0JVH3 Cluster: Aldo/keto reductase; n=17; Bacteria|Rep... 40 0.13 UniRef50_Q6NKP1 Cluster: At5g53580; n=18; cellular organisms|Rep... 40 0.13 UniRef50_A1DD54 Cluster: Aldo/keto reductase; n=3; Trichocomacea... 40 0.13 UniRef50_Q5V1M9 Cluster: Oxidoreductase aldo/keto reductase fami... 40 0.13 UniRef50_Q8EVP7 Cluster: Putative oxidoreductase; n=3; Bacteria|... 40 0.17 UniRef50_Q7NK63 Cluster: Gll1617 protein; n=1; Gloeobacter viola... 40 0.17 UniRef50_Q1EZH4 Cluster: Aldo/keto reductase:4Fe-4S ferredoxin, ... 40 0.17 UniRef50_A1SY15 Cluster: Aldo/keto reductase; n=1; Psychromonas ... 40 0.17 UniRef50_A0L1A2 Cluster: Aldo/keto reductase; n=8; Gammaproteoba... 40 0.17 UniRef50_A4IJ00 Cluster: LOC548351 protein; n=1; Xenopus tropica... 40 0.23 UniRef50_A3WP89 Cluster: Aldo/keto reductase; n=1; Idiomarina ba... 40 0.23 UniRef50_A0L4P0 Cluster: Aldo/keto reductase; n=1; Magnetococcus... 40 0.23 UniRef50_Q94A68 Cluster: Uncharacterized oxidoreductase At1g0669... 40 0.23 UniRef50_Q98EU0 Cluster: Oxidoreductase; MocA; n=27; Bacteria|Re... 39 0.30 UniRef50_Q82JL9 Cluster: Putative oxidoreductase; n=2; Streptomy... 39 0.30 UniRef50_Q3AEN5 Cluster: Oxidoreductase, aldo/keto reductase fam... 39 0.30 UniRef50_Q1FGT0 Cluster: Aldo/keto reductase; n=1; Clostridium p... 39 0.30 UniRef50_Q0RGM0 Cluster: Putative aldoketoreductase; n=2; Franki... 39 0.30 UniRef50_Q9VGF3 Cluster: CG18547-PA; n=7; Endopterygota|Rep: CG1... 39 0.30 UniRef50_Q5KKZ8 Cluster: Aldo-keto reductase, putative; n=2; Fil... 39 0.30 UniRef50_A0QHX8 Cluster: General stress protein 69; n=2; Mycobac... 39 0.40 UniRef50_Q295T6 Cluster: GA14985-PA; n=1; Drosophila pseudoobscu... 39 0.40 UniRef50_Q979I4 Cluster: Aldo / keto reductase; n=3; Archaea|Rep... 39 0.40 UniRef50_Q8ZU65 Cluster: Aldo-keto reductase, putative; n=4; The... 39 0.40 UniRef50_UPI0000DAE567 Cluster: hypothetical protein Rgryl_01000... 38 0.53 UniRef50_Q08NK7 Cluster: Aldo/keto reductase; n=1; Stigmatella a... 38 0.53 UniRef50_A6BIJ0 Cluster: Putative uncharacterized protein; n=1; ... 38 0.53 UniRef50_A6R5B4 Cluster: NAD(P)H-dependent D-xylose reductase; n... 38 0.53 UniRef50_Q4JCC1 Cluster: 2,5-diketo-D-gluconic acid reductase A;... 38 0.53 UniRef50_Q8DK16 Cluster: Tlr1054 protein; n=6; Cyanobacteria|Rep... 38 0.69 UniRef50_Q03X89 Cluster: Aryl-alcohol dehydrogenase family enzym... 38 0.69 UniRef50_A5CYR4 Cluster: Predicted oxidoreductases; n=2; Clostri... 38 0.69 UniRef50_A2UBC7 Cluster: Aldo/keto reductase; n=3; cellular orga... 38 0.69 UniRef50_A4R217 Cluster: Putative uncharacterized protein; n=1; ... 38 0.69 UniRef50_A5UJH5 Cluster: Predicted oxidoreductase, aldo/keto red... 38 0.69 UniRef50_O66660 Cluster: Putative uncharacterized protein; n=1; ... 38 0.92 UniRef50_Q0AQX2 Cluster: Aldo/keto reductase; n=1; Maricaulis ma... 38 0.92 UniRef50_A0YSM3 Cluster: Probable oxidoreductase; n=1; Lyngbya s... 38 0.92 UniRef50_Q5ASJ7 Cluster: Putative uncharacterized protein; n=1; ... 38 0.92 UniRef50_UPI0001556575 Cluster: PREDICTED: similar to Aldo-keto ... 37 1.2 UniRef50_Q8UIN0 Cluster: Oxidoreductase; n=3; Alphaproteobacteri... 37 1.2 UniRef50_Q8EUX1 Cluster: Aldo/keto reductase family oxidoreducta... 37 1.2 UniRef50_Q3ZWR6 Cluster: Oxidoreductase, aldo reductase; n=3; De... 37 1.2 UniRef50_Q7D3N9 Cluster: AGR_pAT_274p; n=3; Proteobacteria|Rep: ... 37 1.2 UniRef50_Q022Y6 Cluster: Aldo/keto reductase precursor; n=2; Sol... 37 1.2 UniRef50_A7HEV1 Cluster: Aldo/keto reductase; n=13; Bacteria|Rep... 37 1.2 UniRef50_A6WAE5 Cluster: Aldo/keto reductase; n=1; Kineococcus r... 37 1.2 UniRef50_A6LWU9 Cluster: Aldo/keto reductase; n=3; Clostridium|R... 37 1.2 UniRef50_A1RJL6 Cluster: Aldo/keto reductase; n=37; Bacteria|Rep... 37 1.2 UniRef50_Q6CWB9 Cluster: Similarities with sp|Q12458 Saccharomyc... 37 1.2 UniRef50_A4QYA4 Cluster: Putative uncharacterized protein; n=1; ... 37 1.2 UniRef50_A1CGI8 Cluster: Aldo-keto reductase (AKR13), puatative;... 37 1.2 UniRef50_Q2NFN7 Cluster: Predicted oxidoreductase; n=1; Methanos... 37 1.2 UniRef50_Q89JX0 Cluster: Oxidoreductase; n=26; Bacteria|Rep: Oxi... 37 1.6 UniRef50_Q93KW0 Cluster: Putative oxidoreductase; n=1; Streptomy... 37 1.6 UniRef50_Q0AL14 Cluster: Aldo/keto reductase; n=1; Maricaulis ma... 37 1.6 UniRef50_A3IX63 Cluster: Putative oxidoreductase; n=1; Cyanothec... 37 1.6 UniRef50_A0LHW7 Cluster: Aldo/keto reductase precursor; n=1; Syn... 37 1.6 UniRef50_A5UNN5 Cluster: Predicted oxidoreductase, aldo/keto red... 37 1.6 UniRef50_Q837G5 Cluster: Oxidoreductase, aldo/keto reductase 2 f... 36 2.1 UniRef50_A7BLU0 Cluster: Aldo/keto reductase family; n=1; Beggia... 36 2.1 UniRef50_A3I2P1 Cluster: Putative oxidoreductase-possibly Aldo/k... 36 2.1 UniRef50_Q2RWD2 Cluster: Aldo/keto reductase; n=1; Rhodospirillu... 36 2.8 UniRef50_A0V7Q3 Cluster: Aldo/keto reductase precursor; n=5; Pro... 36 2.8 UniRef50_Q2SL81 Cluster: Predicted oxidoreductase; n=10; Bacteri... 36 3.7 UniRef50_Q1IXS0 Cluster: Putative aldehyde reductase; n=1; Deino... 36 3.7 UniRef50_Q1IXM8 Cluster: Aldo/keto reductase; n=2; Bacteria|Rep:... 36 3.7 UniRef50_A5VEK4 Cluster: Aldo/keto reductase; n=5; Bacteria|Rep:... 36 3.7 UniRef50_A0K1H5 Cluster: Aldo/keto reductase; n=6; Actinomycetal... 36 3.7 UniRef50_Q0DHN0 Cluster: Os05g0456200 protein; n=2; Oryza sativa... 36 3.7 UniRef50_A2XRY8 Cluster: Putative uncharacterized protein; n=2; ... 36 3.7 UniRef50_P49249 Cluster: IN2-2 protein; n=6; Magnoliophyta|Rep: ... 36 3.7 UniRef50_Q5ZTU6 Cluster: D-xylose reductase III; n=5; Legionella... 35 4.9 UniRef50_Q1GLY3 Cluster: Aldo/keto reductase; n=9; Proteobacteri... 35 4.9 UniRef50_A5FZX7 Cluster: Aldo/keto reductase precursor; n=4; Bac... 35 4.9 UniRef50_A4E7S8 Cluster: Putative uncharacterized protein; n=1; ... 35 4.9 UniRef50_Q983C8 Cluster: Oxido-reductase, and dehydratase; MocA;... 35 6.5 UniRef50_Q8EZ83 Cluster: Aldo/keto reductase family protein; n=1... 35 6.5 UniRef50_Q87SA8 Cluster: Oxidoreductase Tas, aldo/keto reductase... 35 6.5 UniRef50_Q2BBT9 Cluster: Probable oxidoreductase protein; n=2; B... 35 6.5 UniRef50_Q1IQ78 Cluster: Aldo/keto reductase; n=1; Acidobacteria... 35 6.5 UniRef50_Q118N2 Cluster: Putative uncharacterized protein; n=1; ... 35 6.5 UniRef50_Q0FFB1 Cluster: Aldo/keto reductase; n=1; alpha proteob... 35 6.5 UniRef50_Q23TY7 Cluster: Oxidoreductase, aldo/keto reductase fam... 35 6.5 UniRef50_P77256 Cluster: Uncharacterized oxidoreductase ydjG; n=... 35 6.5 UniRef50_P40691 Cluster: Auxin-induced protein PCNT115; n=65; ce... 35 6.5 UniRef50_Q982V1 Cluster: Mll8482 protein; n=9; Alphaproteobacter... 34 8.6 UniRef50_Q8YAN3 Cluster: Lmo0084 protein; n=11; Listeria monocyt... 34 8.6 UniRef50_Q88TP1 Cluster: Oxidoreductase; n=3; Bacteria|Rep: Oxid... 34 8.6 UniRef50_Q7UZ40 Cluster: Putative oxidoreductase-possibly Aldo/k... 34 8.6 UniRef50_Q3A5H0 Cluster: Predicted oxidoreductase, aryl-alcohol ... 34 8.6 UniRef50_Q2JHT1 Cluster: Aldo/keto reductase Tas; n=25; cellular... 34 8.6 UniRef50_A5ZM37 Cluster: Putative uncharacterized protein; n=1; ... 34 8.6 UniRef50_Q338B1 Cluster: Auxin-induced protein PCNT115, putative... 34 8.6 UniRef50_Q5KKC5 Cluster: Putative uncharacterized protein; n=2; ... 34 8.6 UniRef50_Q9YBV5 Cluster: Putative uncharacterized protein; n=1; ... 34 8.6 UniRef50_Q5V3K3 Cluster: Oxidoreductase aldo/keto reductase fami... 34 8.6 UniRef50_Q5V161 Cluster: Aldo/keto reductase; n=2; Halobacteriac... 34 8.6 >UniRef50_Q5BLA6 Cluster: Zgc:110782; n=2; Danio rerio|Rep: Zgc:110782 - Danio rerio (Zebrafish) (Brachydanio rerio) Length = 287 Score = 138 bits (335), Expect = 3e-31 Identities = 71/149 (47%), Positives = 97/149 (65%) Frame = +3 Query: 252 LNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPK 431 L +G +MP +GL T+K+ + Q+V AL+AGYR FDTAA+YGNE +L K+LLPK Sbjct: 8 LMSGTQMPLLGLGTYKLQDHEQLKQSVSCALQAGYRAFDTAAVYGNEAHLGQVLKELLPK 67 Query: 432 YKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLDFENRN 611 Y L R D+FIISKL P ++G A + +L L +YIDLYL+H PG+ LD E+ Sbjct: 68 YGLIREDVFIISKLAPSDHGLRA--KEGCLRSLEQLDCEYIDLYLIHWPGMEGLDPEDSR 125 Query: 612 SSRIRKQTWATLVDLYHDHKIRALGVSNY 698 S R Q+WATL + + + +A+GVSNY Sbjct: 126 HSEYRAQSWATLEEFHASGQFKAIGVSNY 154 >UniRef50_Q5XJM7 Cluster: Zgc:101765; n=5; Eumetazoa|Rep: Zgc:101765 - Danio rerio (Zebrafish) (Brachydanio rerio) Length = 288 Score = 136 bits (329), Expect = 1e-30 Identities = 70/151 (46%), Positives = 91/151 (60%) Frame = +3 Query: 252 LNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPK 431 LNN ++MP +GL TF++ VD ALKAGYR FDTAA+Y NE +L A + LLPK Sbjct: 10 LNNDIQMPLLGLGTFRLQGQEDTYSAVDAALKAGYRAFDTAAVYRNEAHLGHALRCLLPK 69 Query: 432 YKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLDFENRN 611 + L R D+FI SKL P + G A +L LGL YIDLYL+H PG L ++ Sbjct: 70 HGLSREDVFITSKLGPKDQGSKA--RNGCQKSLEQLGLGYIDLYLIHWPGTQGLPVGDKR 127 Query: 612 SSRIRKQTWATLVDLYHDHKIRALGVSNYFI 704 + R Q+W L + Y + K RA+GVSNY + Sbjct: 128 NPENRAQSWRVLEEFYSEGKFRAIGVSNYTV 158 >UniRef50_UPI00015B5BD7 Cluster: PREDICTED: similar to aldo-keto reductase; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to aldo-keto reductase - Nasonia vitripennis Length = 310 Score = 130 bits (315), Expect = 7e-29 Identities = 61/151 (40%), Positives = 94/151 (62%) Frame = +3 Query: 252 LNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPK 431 LNNG +MP +G+ T+K+ + + +D++ G+R DTA +Y NE + A K+LLPK Sbjct: 28 LNNGYDMPLVGIGTYKVRGREVIKRVIDESFAVGFRSIDTAVVYRNEEDIGLALKELLPK 87 Query: 432 YKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLDFENRN 611 Y LKR DIFI SKL P + G ++ ++L L Y+DLYL+H PG ++ + + Sbjct: 88 YNLKREDIFITSKLSPSDNGDPDKIRKSVEDSLKALDTSYLDLYLIHWPGASRILENSPD 147 Query: 612 SSRIRKQTWATLVDLYHDHKIRALGVSNYFI 704 + ++R TWATLV+L +R++GVSNY + Sbjct: 148 NPKLRVTTWATLVELQQKGLLRSIGVSNYTV 178 >UniRef50_UPI0000DB6EE9 Cluster: PREDICTED: similar to C35D10.6; n=2; Endopterygota|Rep: PREDICTED: similar to C35D10.6 - Apis mellifera Length = 292 Score = 124 bits (299), Expect = 6e-27 Identities = 64/151 (42%), Positives = 88/151 (58%) Frame = +3 Query: 252 LNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPK 431 L++G +MP IG T+K+ V Q VD++L G+R DTA Y NE + +A K LLPK Sbjct: 10 LSSGYDMPLIGFGTYKIQGRELVYQVVDESLNVGFRSIDTAVGYRNEEDIGYALKNLLPK 69 Query: 432 YKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLDFENRN 611 Y L+R DIFI +KL P G E+ +L YIDLYL+H PG ++ + N Sbjct: 70 YNLQRSDIFITTKLPPSVNGDPKGIEQCVQKSLKAFNTTYIDLYLIHWPGATRIPETSTN 129 Query: 612 SSRIRKQTWATLVDLYHDHKIRALGVSNYFI 704 + +R +TW LVDL IR++GVSN+ I Sbjct: 130 NPSLRAKTWNKLVDLKKQGFIRSIGVSNFTI 160 >UniRef50_Q5TNP1 Cluster: ENSANGP00000029046; n=2; Culicidae|Rep: ENSANGP00000029046 - Anopheles gambiae str. PEST Length = 331 Score = 117 bits (282), Expect = 7e-25 Identities = 63/163 (38%), Positives = 93/163 (57%), Gaps = 10/163 (6%) Frame = +3 Query: 246 FTLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLL 425 F LN G ++P G T+++ + Q +D AL+AGYR DTA +Y NE Y+ A K LL Sbjct: 34 FKLNTGFDIPLAGFGTYQIHGQELIYQVLDYALEAGYRHIDTAVVYRNEEYIGTALKTLL 93 Query: 426 PKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGI------- 584 PKY LKR DIFI SKL+ + A E+ +L+NL DY+DLYL+H PG+ Sbjct: 94 PKYNLKREDIFITSKLISQSGKDEAFVEQMVRKSLANLQTDYLDLYLIHWPGVSGKCGRW 153 Query: 585 ---YKLDFENRNSSRIRKQTWATLVDLYHDHKIRALGVSNYFI 704 + + + ++ + R +W L L + +R++GVSNY + Sbjct: 154 KWLFGMQVTHPDNVKYRAASWNALSKLEREGCLRSIGVSNYTV 196 >UniRef50_Q6WGK4 Cluster: Aldose reductase; n=1; Pristionchus pacificus|Rep: Aldose reductase - Pristionchus pacificus Length = 293 Score = 115 bits (276), Expect = 4e-24 Identities = 59/145 (40%), Positives = 88/145 (60%) Frame = +3 Query: 270 MPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPKYKLKRG 449 MP IG+ T+++ + T+D+A + GYR DTA +Y NE L LL K+ LKR Sbjct: 16 MPMIGVGTYQVQSQSVLTDTIDEAFRLGYRFIDTAQIYRNEAILGRILPDLLEKHSLKRE 75 Query: 450 DIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLDFENRNSSRIRK 629 DIFI SK+ P N G G T ++ +L++L YIDL L+H PG +L ++++++ R Sbjct: 76 DIFITSKVSPINQGKGK-TSKSVLKSLTDLQTPYIDLVLIHWPGTSRLKSNHKDNAKFRA 134 Query: 630 QTWATLVDLYHDHKIRALGVSNYFI 704 +T+ L L + KIR++GVSNY I Sbjct: 135 ETYVELETLMDEGKIRSIGVSNYEI 159 >UniRef50_Q1U9L6 Cluster: 2,5-didehydrogluconate reductase; n=3; Lactobacillus|Rep: 2,5-didehydrogluconate reductase - Lactobacillus reuteri 100-23 Length = 288 Score = 113 bits (272), Expect = 1e-23 Identities = 65/151 (43%), Positives = 93/151 (61%) Frame = +3 Query: 246 FTLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLL 425 F LNNGV++P +G TF+ Q V +A++ GYR DTAA+YGNE A K + Sbjct: 11 FNLNNGVKIPCVGYGTFRTPADVAE-QAVKEAIETGYRHIDTAAVYGNEE----AVGKGI 65 Query: 426 PKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLDFEN 605 +KR D+F+ SKL N G T++AF TL L +DY+DLYL+H P K F + Sbjct: 66 KDSGIKREDLFVTSKLWNTNRGYEQ-TKKAFQETLDRLQMDYLDLYLIHWPANEK-QFGD 123 Query: 606 RNSSRIRKQTWATLVDLYHDHKIRALGVSNY 698 ++++I +TW + DLY++ KIRA+GVSN+ Sbjct: 124 -DAAKINAETWRAMEDLYNEGKIRAIGVSNF 153 >UniRef50_P70883 Cluster: AkrI; n=1; Butyrivibrio fibrisolvens|Rep: AkrI - Butyrivibrio fibrisolvens Length = 172 Score = 110 bits (264), Expect = 1e-22 Identities = 59/155 (38%), Positives = 86/155 (55%) Frame = +3 Query: 234 LPQQFTLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAF 413 L + LNNG +P G T+K+ +V ALK GYR DTAA Y NE ++ A Sbjct: 4 LTTRIKLNNGTAIPMFGYGTYKIKDQNEAYNSVRLALKNGYRHIDTAAFYENEKFVANAI 63 Query: 414 KKLLPKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKL 593 K + + + KR DIF+ SK G T AF T++ + +DY+DLYLVH P Y Sbjct: 64 KDFMEESQTKREDIFVTSKAWKTELGYDK-TLAAFEKTMNEMQMDYLDLYLVHWPASYAF 122 Query: 594 DFENRNSSRIRKQTWATLVDLYHDHKIRALGVSNY 698 D + N++R QTW + ++Y +++A+GVSN+ Sbjct: 123 DDDWENTNR---QTWKAMTEIYKSGRVKAIGVSNF 154 >UniRef50_Q54NR2 Cluster: Aldo-keto reductase; n=3; Dictyostelium discoideum AX4|Rep: Aldo-keto reductase - Dictyostelium discoideum AX4 Length = 305 Score = 108 bits (260), Expect = 3e-22 Identities = 63/171 (36%), Positives = 97/171 (56%), Gaps = 8/171 (4%) Frame = +3 Query: 216 EDFKYILPQQFTLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEV 395 E+ +I+ + LN ++MP +G+ TFK+ +++ L+ GYR DTA++Y NE Sbjct: 10 ENENFIILNELNLNP-IKMPMLGIGTFKLNDIENIIKV---GLENGYRRIDTASMYNNEE 65 Query: 396 YLNFAFKKLLPKY------KLKRGDIFIISKLLPCNY--GGGAVTERAFHNTLSNLGLDY 551 + +++ K K+KR D+FI SK C++ G +AF ++L L LDY Sbjct: 66 RIGKVLNEMVTKNDGLDGKKIKREDLFITSK---CSFMEQGYENALKAFESSLKKLQLDY 122 Query: 552 IDLYLVHNPGIYKLDFENRNSSRIRKQTWATLVDLYHDHKIRALGVSNYFI 704 +D YL+H PG+ LD + +S R QTW L LY D K+R++GVSNY I Sbjct: 123 LDCYLIHWPGVKGLDGSDSGNSIQRAQTWRALEKLYQDKKVRSIGVSNYTI 173 >UniRef50_Q21274 Cluster: Putative uncharacterized protein; n=1; Caenorhabditis elegans|Rep: Putative uncharacterized protein - Caenorhabditis elegans Length = 301 Score = 108 bits (259), Expect = 4e-22 Identities = 62/165 (37%), Positives = 91/165 (55%), Gaps = 3/165 (1%) Frame = +3 Query: 222 FKYILPQQFTLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYL 401 F ++ F ++G EMP IGL ++ + +++ ALK+GYR FDTA LY NE +L Sbjct: 4 FTNVVGGAFKFSDGYEMPKIGLGISRIETQQDLDVSIEAALKSGYRQFDTANLYKNETFL 63 Query: 402 NFAFKKLLPKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNP- 578 + KK LP++ L R D+FI +K+ N TE+ N+L+ L DY+DL L+H P Sbjct: 64 GNSLKKYLPQFGLTREDVFITTKVRTLNENTVEETEKQLANSLATLQTDYVDLLLIHYPR 123 Query: 579 --GIYKLDFENRNSSRIRKQTWATLVDLYHDHKIRALGVSNYFIW 707 D N SR RK W TL ++R++GVSNY ++ Sbjct: 124 DRDTGNDDDYEINKSR-RKIVWQTLEKAKESGRVRSIGVSNYEVY 167 >UniRef50_Q18483 Cluster: Putative uncharacterized protein; n=2; Caenorhabditis|Rep: Putative uncharacterized protein - Caenorhabditis elegans Length = 287 Score = 108 bits (259), Expect = 4e-22 Identities = 59/155 (38%), Positives = 91/155 (58%) Frame = +3 Query: 240 QQFTLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKK 419 +++ NN MP IG+ T+++ + Q +D K GYR DTA +Y NE + +K Sbjct: 4 REYVKNN---MPLIGIGTWQVQKEEILRQVIDAGFKEGYRFIDTAQVYNNEAKIGRILEK 60 Query: 420 LLPKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLDF 599 LLP LKR DI+I SKL P N G E + +LSNL ++Y+DL L+H PG L Sbjct: 61 LLPANGLKREDIWITSKLAPSNAGVKKARE-SIEESLSNLKVEYLDLLLIHWPG-SSLKS 118 Query: 600 ENRNSSRIRKQTWATLVDLYHDHKIRALGVSNYFI 704 EN + ++R ++W + ++ + K+R++GVSN+ I Sbjct: 119 ENPANKKLRVESWNVMCEMMAEGKLRSVGVSNFEI 153 >UniRef50_Q17568 Cluster: Putative uncharacterized protein; n=1; Caenorhabditis elegans|Rep: Putative uncharacterized protein - Caenorhabditis elegans Length = 287 Score = 107 bits (258), Expect = 6e-22 Identities = 60/152 (39%), Positives = 84/152 (55%), Gaps = 1/152 (0%) Frame = +3 Query: 246 FTLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLL 425 F L NG E+P + L T++ + VD+ALK GYR FDTA Y NE L A K LL Sbjct: 2 FKLKNGQEIPKLALGTYE-AKGDQLFAAVDEALKVGYRSFDTAKYYENEKDLGLALKTLL 60 Query: 426 PKYKLKRGDIFIISKLLPCNYGGGA-VTERAFHNTLSNLGLDYIDLYLVHNPGIYKLDFE 602 P++ + DI++ SK+ P + A + + + +L L Y+DL LVH P + Sbjct: 61 PRHNICSEDIYLTSKVFPYSSKNAAELIRKDVNESLELLDRKYLDLVLVHYPRPLDTEDL 120 Query: 603 NRNSSRIRKQTWATLVDLYHDHKIRALGVSNY 698 N N+ RK TW L L+ + KIR++GVSNY Sbjct: 121 NENNKMYRKDTWIALEKLHAEGKIRSIGVSNY 152 >UniRef50_P91997 Cluster: Putative uncharacterized protein; n=4; Caenorhabditis|Rep: Putative uncharacterized protein - Caenorhabditis elegans Length = 297 Score = 106 bits (255), Expect = 1e-21 Identities = 61/151 (40%), Positives = 83/151 (54%) Frame = +3 Query: 252 LNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPK 431 LN+G +P +G T+K+ V +D AL AGYRMFDTA Y NE L A K LLPK Sbjct: 15 LNSGYNIPFVGFGTYKVTG-ENVPPAIDAALTAGYRMFDTAKYYLNEKELGEALKILLPK 73 Query: 432 YKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLDFENRN 611 + L R D+F+ SK P + +L +L DYID+YLVH P D ++ N Sbjct: 74 HGLSRSDVFLTSKFFPESKNCREACRGFVEESLQSLQTDYIDMYLVHYPKPNDSDNDDVN 133 Query: 612 SSRIRKQTWATLVDLYHDHKIRALGVSNYFI 704 ++ RK + L + K+R++GVSNY I Sbjct: 134 NAEYRKIAYEVLEEAKAAGKVRSIGVSNYEI 164 >UniRef50_A6NPD6 Cluster: Putative uncharacterized protein; n=3; Bacteria|Rep: Putative uncharacterized protein - Bacteroides capillosus ATCC 29799 Length = 287 Score = 104 bits (250), Expect = 5e-21 Identities = 60/152 (39%), Positives = 87/152 (57%) Frame = +3 Query: 243 QFTLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKL 422 QF L+NG+ +PA+G T+K G + + + +A+ GYR FDTA+ YG E L A Sbjct: 7 QFVLSNGLSIPAVGFGTYKTGDGDSAV--LSNAIAQGYRHFDTASFYGTETALGQA---- 60 Query: 423 LPKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLDFE 602 + + + R D F+ SKL G A RAF TL LG DY+DLYL+H P + D E Sbjct: 61 VAESDIPREDFFLTSKLWKTEMGYDAAL-RAFDATLERLGTDYLDLYLIHWP---RPDLE 116 Query: 603 NRNSSRIRKQTWATLVDLYHDHKIRALGVSNY 698 + +++ ++TW L LY +RA+GVSN+ Sbjct: 117 LEDWAKLDRETWRALERLYESGLVRAIGVSNF 148 >UniRef50_A6ESC0 Cluster: ARA1; n=1; unidentified eubacterium SCB49|Rep: ARA1 - unidentified eubacterium SCB49 Length = 280 Score = 103 bits (248), Expect = 9e-21 Identities = 58/155 (37%), Positives = 87/155 (56%) Frame = +3 Query: 234 LPQQFTLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAF 413 + + F LNN + +PAIG T++ T + + A+ AGY+ D AA+Y NE + Sbjct: 1 MKEYFKLNNNINIPAIGFGTWQTPDGQTAINAIKTAIDAGYKHIDAAAIYKNEKGVGLGI 60 Query: 414 KKLLPKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKL 593 K+ + R D+F+ SK+ G T +AF NT+++L LDY+DLYL+H P Sbjct: 61 KEA----NIDRKDLFVTSKVWN-EQRGYENTLKAFDNTINDLQLDYLDLYLIHWPAAAH- 114 Query: 594 DFENRNSSRIRKQTWATLVDLYHDHKIRALGVSNY 698 FE N ++ TW+ + LY D KI+ALGVSN+ Sbjct: 115 QFE--NWKQLNNDTWSAMEKLYKDGKIKALGVSNF 147 >UniRef50_Q88SL1 Cluster: Oxidoreductase; n=51; Lactobacillales|Rep: Oxidoreductase - Lactobacillus plantarum Length = 286 Score = 101 bits (243), Expect = 4e-20 Identities = 59/157 (37%), Positives = 88/157 (56%), Gaps = 2/157 (1%) Frame = +3 Query: 234 LPQQFTLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAF 413 L +TLNNG ++P +G T++ +V ALKAGYR DTAA YGNE + Sbjct: 7 LTDTYTLNNGTKIPIVGFGTWQTPDGQVAYDSVLAALKAGYRHIDTAAAYGNEESVG--- 63 Query: 414 KKLLPKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVH--NPGIY 587 K + + R D+F+ +KL ++G A ++A +L+ LGLDY+DLYL+H NP Sbjct: 64 -KAIADSGVAREDLFVTTKLWNADHGYDA-AKKALDTSLAKLGLDYVDLYLIHWPNPAAM 121 Query: 588 KLDFENRNSSRIRKQTWATLVDLYHDHKIRALGVSNY 698 + ++E N+ TW + + Y K RA+GVSN+ Sbjct: 122 RDNWEQLNA-----DTWRAMEEAYTARKARAIGVSNF 153 >UniRef50_Q5FLI5 Cluster: Aldehyde reductase; n=2; Bacteria|Rep: Aldehyde reductase - Lactobacillus acidophilus Length = 278 Score = 99 bits (238), Expect = 2e-19 Identities = 60/151 (39%), Positives = 86/151 (56%) Frame = +3 Query: 249 TLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLP 428 TLNNG++MP +G +++ Q V+D L+ GYR+ DTA +YGNE + A K Sbjct: 6 TLNNGIKMPRLGFGVYQIDDLAQAQQVVEDGLEVGYRLVDTAQIYGNEQAVGDAIK---- 61 Query: 429 KYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLDFENR 608 + R DIFI SK+ +YG T +AF +++ L LDYIDLYL+H P Y D+ Sbjct: 62 HSNVPREDIFITSKIWVDDYGYDN-TLKAFDDSMKKLQLDYIDLYLIHKP--YN-DYYG- 116 Query: 609 NSSRIRKQTWATLVDLYHDHKIRALGVSNYF 701 TW L LY + +IRA+GVS+++ Sbjct: 117 --------TWRALERLYQEGRIRAIGVSSFW 139 >UniRef50_Q8F1G4 Cluster: Aldehyde reductase; n=8; Bacteria|Rep: Aldehyde reductase - Leptospira interrogans Length = 278 Score = 99.5 bits (237), Expect = 2e-19 Identities = 61/157 (38%), Positives = 84/157 (53%) Frame = +3 Query: 234 LPQQFTLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAF 413 L Q LNNG+ MP +GL +K + V +AL+AGYR DTA +Y NEV + A Sbjct: 8 LKQTIMLNNGISMPILGLGVWKTKSGKECKEAVLNALEAGYRHIDTARIYDNEVDVGQAI 67 Query: 414 KKLLPKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKL 593 + + + R +IFI +KL + G T +A N+L LG+D++DLYL+H P K Sbjct: 68 R----ESGIPRKEIFITTKLWNADQGSDK-TRKALENSLDRLGIDFVDLYLIHFPVTSK- 121 Query: 594 DFENRNSSRIRKQTWATLVDLYHDHKIRALGVSNYFI 704 R +W L LYHD +A+GVSNY I Sbjct: 122 ----------RMDSWKELEKLYHDKLCKAIGVSNYTI 148 >UniRef50_Q838E0 Cluster: Oxidoreductase, aldo/keto reductase family; n=24; Bacilli|Rep: Oxidoreductase, aldo/keto reductase family - Enterococcus faecalis (Streptococcus faecalis) Length = 279 Score = 99.1 bits (236), Expect = 3e-19 Identities = 59/155 (38%), Positives = 88/155 (56%) Frame = +3 Query: 234 LPQQFTLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAF 413 L TLNNG ++P +GL F++ T + V++ + GYR+ DTA +YGNE Sbjct: 5 LADTVTLNNGTKIPGMGLGVFQIPDEETA-KVVEEGIINGYRLIDTAQIYGNESGTGAGI 63 Query: 414 KKLLPKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKL 593 K L L R D+F+ SK+ + T +AF+++L LGLDY+DLYL+H PG Sbjct: 64 KAGLAATGLNREDLFVTSKVWNAHISYDE-TIQAFNDSLERLGLDYLDLYLIHWPG---- 118 Query: 594 DFENRNSSRIRKQTWATLVDLYHDHKIRALGVSNY 698 N+S K++W L LY + K++A+GVSN+ Sbjct: 119 -----NNS--YKESWQALETLYAEGKVKAIGVSNF 146 >UniRef50_Q23320 Cluster: Putative uncharacterized protein; n=4; Caenorhabditis|Rep: Putative uncharacterized protein - Caenorhabditis elegans Length = 320 Score = 97.9 bits (233), Expect = 6e-19 Identities = 61/151 (40%), Positives = 83/151 (54%) Frame = +3 Query: 246 FTLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLL 425 FTL+NGV MP+IGL T++M + +A+ AGYR DTA LY NE + A +L Sbjct: 8 FTLSNGVLMPSIGLGTWQMTG-EEGKTVIRNAVLAGYRHIDTATLYQNEHQIGDALAELF 66 Query: 426 PKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLDFEN 605 + LKR DIFI +K C+ V E A N+L L LDY+DLYL H P K D Sbjct: 67 AEGILKREDIFITTKAF-CHEVAPDVVEEALRNSLKRLRLDYVDLYLAHIPASTKDDGSF 125 Query: 606 RNSSRIRKQTWATLVDLYHDHKIRALGVSNY 698 R+ ++ + W +Y +A+GVSN+ Sbjct: 126 RSDVKV-EDIWRGFEKVYGLGLTKAIGVSNF 155 >UniRef50_Q9X0A2 Cluster: Oxidoreductase, aldo/keto reductase family; n=21; Bacteria|Rep: Oxidoreductase, aldo/keto reductase family - Thermotoga maritima Length = 286 Score = 95.9 bits (228), Expect = 2e-18 Identities = 56/151 (37%), Positives = 90/151 (59%) Frame = +3 Query: 249 TLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLP 428 TLNNGVEMP +G F++ T + V +A+K GYR+ DTAA Y NE + A K+ + Sbjct: 7 TLNNGVEMPILGYGVFQIPPEKTE-ECVYEAIKVGYRLIDTAASYMNEEGVGRAIKRAID 65 Query: 429 KYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLDFENR 608 + ++R ++F+ +KL + G + T++AF +L L L+YIDLYL+H P F + Sbjct: 66 EGIVRREELFVTTKLWVSDVGYES-TKKAFEKSLKKLQLEYIDLYLIHQP------FGDV 118 Query: 609 NSSRIRKQTWATLVDLYHDHKIRALGVSNYF 701 + + W + ++Y D +RA+GVSN++ Sbjct: 119 HCA------WKAMEEMYKDGLVRAIGVSNFY 143 >UniRef50_Q05KR9 Cluster: Benzil reductase; n=5; Bacillales|Rep: Benzil reductase - Bacillus subtilis Length = 276 Score = 95.9 bits (228), Expect = 2e-18 Identities = 62/149 (41%), Positives = 81/149 (54%) Frame = +3 Query: 252 LNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPK 431 L+NGVEMP GL FK+ + ++V A+K GYR DTAA+Y NE + K + Sbjct: 11 LHNGVEMPWFGLGVFKVENGNEATESVKAAIKNGYRSIDTAAIYKNEEGVGIGIK----E 66 Query: 432 YKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLDFENRN 611 + R ++FI SK+ + G T AF +L L LDY+DLYL+H PG K Sbjct: 67 SGVAREELFITSKVWNEDQ-GYETTLAAFEKSLERLQLDYLDLYLIHWPGKDKY------ 119 Query: 612 SSRIRKQTWATLVDLYHDHKIRALGVSNY 698 K TW L LY D KIRA+GVSN+ Sbjct: 120 -----KDTWRALEKLYKDGKIRAIGVSNF 143 >UniRef50_Q5HR31 Cluster: Oxidoreductase, aldo/keto reductase family; n=3; Staphylococcus|Rep: Oxidoreductase, aldo/keto reductase family - Staphylococcus epidermidis (strain ATCC 35984 / RP62A) Length = 279 Score = 94.3 bits (224), Expect = 8e-18 Identities = 62/151 (41%), Positives = 86/151 (56%) Frame = +3 Query: 252 LNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPK 431 LNNG MPA+GL +K+ + + V AL AGYR FDTA YGNE L A K Sbjct: 8 LNNGYPMPAVGLGVYKIAD-EQMEEVVRTALDAGYRAFDTAYFYGNEKALGSALKHS--- 63 Query: 432 YKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLDFENRN 611 ++R ++FI SKL +Y G T F+ +L NLGLDY+DL+L+H P EN Sbjct: 64 -NVERDELFITSKLWN-DYQGYDQTIEYFNKSLDNLGLDYLDLFLIHWP------CEN-- 113 Query: 612 SSRIRKQTWATLVDLYHDHKIRALGVSNYFI 704 ++ +++ L LY + KI+A+GV N+ I Sbjct: 114 -DQLYIESYKALEHLYEEGKIKAIGVCNFKI 143 >UniRef50_Q2V420 Cluster: Uncharacterized protein At2g37770.1; n=1; Arabidopsis thaliana|Rep: Uncharacterized protein At2g37770.1 - Arabidopsis thaliana (Mouse-ear cress) Length = 283 Score = 93.1 bits (221), Expect = 2e-17 Identities = 59/155 (38%), Positives = 82/155 (52%), Gaps = 4/155 (2%) Frame = +3 Query: 246 FTLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLL 425 F LN G + P++GL T++ V V A+K GYR D A +YGNE + KKL Sbjct: 8 FKLNTGAKFPSVGLGTWQASPGL-VGDAVAAAVKIGYRHIDCAQIYGNEKEIGAVLKKLF 66 Query: 426 PKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYK---LD 596 +KR D+FI SKL ++ V E A + TL +L L+Y+DLYL+H P K + Sbjct: 67 EDRVVKREDLFITSKLWCTDHDPQDVPE-ALNRTLKDLQLEYVDLYLIHWPARIKKGSVG 125 Query: 597 FENRNSSRIR-KQTWATLVDLYHDHKIRALGVSNY 698 + N + TW + LY K RA+GVSN+ Sbjct: 126 IKPENLLPVDIPSTWKAMEALYDSGKARAIGVSNF 160 >UniRef50_Q0PGJ6 Cluster: Aldo-keto reductase; n=32; Magnoliophyta|Rep: Aldo-keto reductase - Arabidopsis thaliana (Mouse-ear cress) Length = 315 Score = 93.1 bits (221), Expect = 2e-17 Identities = 59/155 (38%), Positives = 82/155 (52%), Gaps = 4/155 (2%) Frame = +3 Query: 246 FTLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLL 425 F LN G + P++GL T++ V V A+K GYR D A +YGNE + KKL Sbjct: 8 FKLNTGAKFPSVGLGTWQASPGL-VGDAVAAAVKIGYRHIDCAQIYGNEKEIGAVLKKLF 66 Query: 426 PKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYK---LD 596 +KR D+FI SKL ++ V E A + TL +L L+Y+DLYL+H P K + Sbjct: 67 EDRVVKREDLFITSKLWCTDHDPQDVPE-ALNRTLKDLQLEYVDLYLIHWPARIKKGSVG 125 Query: 597 FENRNSSRIR-KQTWATLVDLYHDHKIRALGVSNY 698 + N + TW + LY K RA+GVSN+ Sbjct: 126 IKPENLLPVDIPSTWKAMEALYDSGKARAIGVSNF 160 >UniRef50_P45376 Cluster: Aldose reductase; n=21; Bilateria|Rep: Aldose reductase - Mus musculus (Mouse) Length = 316 Score = 93.1 bits (221), Expect = 2e-17 Identities = 57/158 (36%), Positives = 84/158 (53%), Gaps = 9/158 (5%) Frame = +3 Query: 252 LNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPK 431 LNNG +MP +GL T+K V + V A+ GYR D A +Y NE + A ++ L + Sbjct: 7 LNNGTKMPTLGLGTWKSPPGQ-VTEAVKVAIDLGYRHIDCAQVYQNEKEVGVALQEKLKE 65 Query: 432 YKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVH-------NPGIYK 590 +KR D+FI+SKL C + ++ + AF TLS+L LDY+DLYL+H P + Sbjct: 66 QVVKRQDLFIVSKLW-CTFHDKSMVKGAFQKTLSDLQLDYLDLYLIHWPTGFKPGPDYFP 124 Query: 591 LDFENR--NSSRIRKQTWATLVDLYHDHKIRALGVSNY 698 LD S TW + L + ++ +GVSN+ Sbjct: 125 LDASGNVIPSDTDFVDTWTAMEQLVDEGLVKTIGVSNF 162 >UniRef50_P15121 Cluster: Aldose reductase; n=72; Eumetazoa|Rep: Aldose reductase - Homo sapiens (Human) Length = 316 Score = 91.9 bits (218), Expect = 4e-17 Identities = 60/165 (36%), Positives = 91/165 (55%), Gaps = 10/165 (6%) Frame = +3 Query: 234 LPQQFTLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAF 413 + + LNNG +MP +GL T+K V + V A+ GYR D A +Y NE + A Sbjct: 1 MASRLLLNNGAKMPILGLGTWKSPPGQ-VTEAVKVAIDVGYRHIDCAHVYQNENEVGVAI 59 Query: 414 KKLLPKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVH-----NP 578 ++ L + +KR ++FI+SKL C Y + + A TLS+L LDY+DLYL+H P Sbjct: 60 QEKLREQVVKREELFIVSKLW-CTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKP 118 Query: 579 G--IYKLDFENRN---SSRIRKQTWATLVDLYHDHKIRALGVSNY 698 G + LD E+ N S TWA + +L + ++A+G+SN+ Sbjct: 119 GKEFFPLD-ESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNF 162 >UniRef50_Q03TW0 Cluster: Aldo/keto reductase of diketogulonate reductase family; n=1; Lactobacillus brevis ATCC 367|Rep: Aldo/keto reductase of diketogulonate reductase family - Lactobacillus brevis (strain ATCC 367 / JCM 1170) Length = 293 Score = 91.1 bits (216), Expect = 7e-17 Identities = 57/149 (38%), Positives = 80/149 (53%) Frame = +3 Query: 252 LNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPK 431 +NNG ++P +GL F++ + + AL AGYR DTAA YGNE ++ A + + Sbjct: 16 MNNGHQIPQLGLGVFQVDNAEDTKNAIKWALAAGYRHIDTAAYYGNEQWVGEAIR----E 71 Query: 432 YKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLDFENRN 611 + R IF+ SKL + G T+ AF TL LGLDY+DLYL+H P LD Sbjct: 72 SDVPRDQIFVTSKLWN-SVRGYDETQAAFQETLDKLGLDYLDLYLIHWPAPGYLD----- 125 Query: 612 SSRIRKQTWATLVDLYHDHKIRALGVSNY 698 +W + DLY KI+ +GVSN+ Sbjct: 126 -------SWRAMEDLYKAGKIKNIGVSNF 147 >UniRef50_Q8CI22 Cluster: 2310005E10Rik protein; n=30; Tetrapoda|Rep: 2310005E10Rik protein - Mus musculus (Mouse) Length = 316 Score = 90.6 bits (215), Expect = 9e-17 Identities = 59/159 (37%), Positives = 89/159 (55%), Gaps = 9/159 (5%) Frame = +3 Query: 249 TLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLP 428 TL G +MP +GL T+K V + V A+ AGYR D A +Y NE + A ++ + Sbjct: 6 TLLTGAKMPIVGLGTWKSPPA-KVREAVKVAIDAGYRHIDCAYVYQNESEVGEAIQEKIQ 64 Query: 429 KYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNP-----GIYKL 593 + +KR D+FI+SKL + ++ ++AF NTLS+L LDY+DLYL+H P G L Sbjct: 65 EKAVKREDLFIVSKLW-STFFEKSLVKKAFQNTLSDLKLDYLDLYLIHWPQGFQSGNVFL 123 Query: 594 DFENRNSSRIRKQT----WATLVDLYHDHKIRALGVSNY 698 +++ S K T W + +L ++ALGVSN+ Sbjct: 124 PTDDKGSILSSKYTFLDAWEAMEELVDQGLVKALGVSNF 162 >UniRef50_Q41E86 Cluster: 2,5-didehydrogluconate reductase; n=2; Bacteria|Rep: 2,5-didehydrogluconate reductase - Exiguobacterium sibiricum 255-15 Length = 274 Score = 90.6 bits (215), Expect = 9e-17 Identities = 58/152 (38%), Positives = 79/152 (51%) Frame = +3 Query: 249 TLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLP 428 TLNNG+ MP +G FK+ V + V +AL+ GYR DTA +Y NE + A K Sbjct: 5 TLNNGLVMPQLGYGVFKVPE-QEVYEAVREALRVGYRSIDTAMIYENEAGVGRALKDS-- 61 Query: 429 KYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLDFENR 608 + R DIF+ +K+ + G T AF +L LG+DY+DLYL+H P Sbjct: 62 --GIPREDIFLTTKVWNKDQGYER-TLAAFETSLQKLGVDYVDLYLIHWP---------M 109 Query: 609 NSSRIRKQTWATLVDLYHDHKIRALGVSNYFI 704 + TW L LY D K +A+GVSN+ I Sbjct: 110 PDEDLYMDTWRALEQLYRDGKAKAIGVSNFHI 141 >UniRef50_Q9VHX4 Cluster: CG2767-PA; n=4; Endopterygota|Rep: CG2767-PA - Drosophila melanogaster (Fruit fly) Length = 329 Score = 90.6 bits (215), Expect = 9e-17 Identities = 57/161 (35%), Positives = 84/161 (52%), Gaps = 11/161 (6%) Frame = +3 Query: 249 TLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLP 428 T NNG +MP IG+ T++ + +D AL+AGYR DTA +YGNE + K+ L Sbjct: 8 TFNNGEKMPVIGIGTWQASD-EEIETAIDAALEAGYRHIDTAPVYGNEKAIGRVLKRWLD 66 Query: 429 KYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNP--------GI 584 K+KR ++FI++K+ P + V E +L +L LDY+DLYLVH P G Sbjct: 67 AGKVKREELFIVTKVPPVSNRPHEV-EPTIKKSLEDLQLDYVDLYLVHTPFTININEDGS 125 Query: 585 YKLDFENRNSSRI---RKQTWATLVDLYHDHKIRALGVSNY 698 +KLD E + W + L +++GVSN+ Sbjct: 126 FKLDKEGLMEVDVTTNHAAIWVAMEALVEKGLTKSIGVSNF 166 >UniRef50_Q03PG5 Cluster: Aldo/keto reductase of diketogulonate reductase family; n=1; Lactobacillus brevis ATCC 367|Rep: Aldo/keto reductase of diketogulonate reductase family - Lactobacillus brevis (strain ATCC 367 / JCM 1170) Length = 268 Score = 89.8 bits (213), Expect = 2e-16 Identities = 58/149 (38%), Positives = 78/149 (52%) Frame = +3 Query: 252 LNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPK 431 L+NGV +P +G T+ + V + AL AGYR D A +YGNE + A K Sbjct: 6 LSNGVTIPMLGFGTYLIDS-KDVPAAIKTALDAGYRHLDCAHIYGNEPAVGEAIKAS--- 61 Query: 432 YKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLDFENRN 611 + R D+FI SK+ + G T AF TLS+L LDY+DLYL+H P N + Sbjct: 62 -GIDRSDLFITSKVWNADQGYDK-TLAAFDQTLSDLQLDYLDLYLIHWP--------NED 111 Query: 612 SSRIRKQTWATLVDLYHDHKIRALGVSNY 698 + TW L LY K+RA+GVSN+ Sbjct: 112 DFELTLDTWRVLETLYQQKKVRAIGVSNF 140 >UniRef50_Q16K66 Cluster: Aldo-keto reductase; n=2; Aedes aegypti|Rep: Aldo-keto reductase - Aedes aegypti (Yellowfever mosquito) Length = 303 Score = 89.8 bits (213), Expect = 2e-16 Identities = 55/155 (35%), Positives = 85/155 (54%), Gaps = 6/155 (3%) Frame = +3 Query: 252 LNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPK 431 LNNG +P IGL T+K+ V + A++ GYR+ DTA +Y NE + A +++ + Sbjct: 4 LNNGHSIPPIGLGTYKITGSDGVA-AIKSAVEFGYRLIDTAFVYNNEQVVGQALREIFSQ 62 Query: 432 YK-LKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLDFENR 608 + R D+FI+SKL P + AV E+ +L LGLDY+DLYL+H P + + Sbjct: 63 GNDINREDVFIVSKLGPTFHRPEAV-EKGCRLSLERLGLDYVDLYLMHTPVAARDSGDGN 121 Query: 609 NSSRIRK-----QTWATLVDLYHDHKIRALGVSNY 698 + S I +TW L + +R++GVSN+ Sbjct: 122 DRSEIDDEVTPLETWKALEECQRKGLVRSIGVSNF 156 >UniRef50_Q5FK98 Cluster: Oxidoreductase; n=8; Lactobacillales|Rep: Oxidoreductase - Lactobacillus acidophilus Length = 285 Score = 89.4 bits (212), Expect = 2e-16 Identities = 53/155 (34%), Positives = 86/155 (55%) Frame = +3 Query: 234 LPQQFTLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAF 413 L +TLNNGV++P IG T++ ++V AL GYR DTA+ YGNE + Sbjct: 6 LQDTYTLNNGVKIPIIGFGTWQTPDGEVAEESVLAALNCGYRHIDTASAYGNEDSVG--- 62 Query: 414 KKLLPKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKL 593 + + K + R ++FI +KL ++ G T++A +L +L LDY+D+YL+H P + Sbjct: 63 -RAIQKSGINRHELFITTKLWNSDH-GYEKTKKAIDQSLLDLKLDYLDMYLIHWPNPSSM 120 Query: 594 DFENRNSSRIRKQTWATLVDLYHDHKIRALGVSNY 698 + + I ++W + + KIRA+GVSN+ Sbjct: 121 ---RDHWAEINAESWRAMEEAVRAGKIRAIGVSNF 152 >UniRef50_A2UAH0 Cluster: Aldo/keto reductase; n=1; Bacillus coagulans 36D1|Rep: Aldo/keto reductase - Bacillus coagulans 36D1 Length = 273 Score = 89.4 bits (212), Expect = 2e-16 Identities = 53/157 (33%), Positives = 81/157 (51%) Frame = +3 Query: 234 LPQQFTLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAF 413 L + F L NGV +P IGL T+++ + T V ALK GYR DTA Y NE + Sbjct: 4 LHETFVLENGVAIPKIGLGTWQVPNGETTYHAVSFALKNGYRHIDTAYAYHNEESVG--- 60 Query: 414 KKLLPKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKL 593 K + + R DIF+ SK LP + F T+ N GL+ +DLYL+H P + Sbjct: 61 -KAVRDSGIDRRDIFVTSK-LPAEIKSYDKALKTFDETMGNFGLEQLDLYLIHAP--WPW 116 Query: 594 DFENRNSSRIRKQTWATLVDLYHDHKIRALGVSNYFI 704 + + ++ + W + ++Y + RA+GVSN+ + Sbjct: 117 SEKGADYTKENIEVWKAMEEIYESGRCRAIGVSNFSV 153 >UniRef50_A6LZ55 Cluster: 2,5-didehydrogluconate reductase; n=1; Clostridium beijerinckii NCIMB 8052|Rep: 2,5-didehydrogluconate reductase - Clostridium beijerinckii NCIMB 8052 Length = 289 Score = 88.6 bits (210), Expect = 4e-16 Identities = 51/149 (34%), Positives = 81/149 (54%) Frame = +3 Query: 258 NGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPKYK 437 NG+++P +G +K+ V +A+K GYR FDTA +YGNE L A + K + Sbjct: 12 NGIKIPQVGFGVYKLNKGEDFETAVGEAIKIGYRHFDTAKIYGNEKDLGLA----IEKSQ 67 Query: 438 LKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLDFENRNSS 617 + R + FI SK+ ++G A T++AF T L ++Y+D+YL+H Y L Sbjct: 68 IPREEFFITSKVWNTDHGYEA-TKKAFEQTCKKLNVEYLDMYLIHFASSYYL-------- 118 Query: 618 RIRKQTWATLVDLYHDHKIRALGVSNYFI 704 +TW + +LY KI+ +GV+N+ I Sbjct: 119 ----ETWHAMEELYLQGKIKVIGVANFQI 143 >UniRef50_Q09632 Cluster: Probable oxidoreductase ZK1290.5; n=2; Caenorhabditis|Rep: Probable oxidoreductase ZK1290.5 - Caenorhabditis elegans Length = 321 Score = 88.6 bits (210), Expect = 4e-16 Identities = 56/153 (36%), Positives = 80/153 (52%), Gaps = 2/153 (1%) Frame = +3 Query: 252 LNNGVEMPAIGLDTFKMGHFY--TVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLL 425 L+N VEMP IGL T G +Y VL ++ K GYR+ DTA YG E L A K Sbjct: 7 LSNNVEMPLIGLGTTHSGGYYHDAVLHSIK---KCGYRLIDTAKRYGVEKQLGIAVKNC- 62 Query: 426 PKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLDFEN 605 + R ++F+ +KL P + G AF + L DY+D+Y++H P +L Sbjct: 63 ---SVPREEMFLSTKLWPVDCGDEVYN--AFQTSCEKLQTDYLDMYMIHMP---QLPDWI 114 Query: 606 RNSSRIRKQTWATLVDLYHDHKIRALGVSNYFI 704 N +++TW + LY D +R++GVSNY I Sbjct: 115 VNQKETKEKTWRQMELLYEDEHVRSIGVSNYSI 147 >UniRef50_Q03XK0 Cluster: Aldo/keto reductase of diketogulonate reductase family; n=3; Lactobacillales|Rep: Aldo/keto reductase of diketogulonate reductase family - Leuconostoc mesenteroides subsp. mesenteroides (strain ATCC 8293 /NCDO 523) Length = 292 Score = 88.2 bits (209), Expect = 5e-16 Identities = 53/152 (34%), Positives = 80/152 (52%) Frame = +3 Query: 249 TLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLP 428 TL +G+EMP +G F++ Q V DA+K GYR+ DTAA YGNE + A + + Sbjct: 5 TLASGIEMPLLGFGVFQVQEKGAAKQAVLDAIKTGYRLIDTAASYGNEREVGEAILEAIN 64 Query: 429 KYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLDFENR 608 + +KR ++F+ SK+ + T A ++L L LDY+DLYL+H P Y F Sbjct: 65 QGIVKREELFVTSKMWVQDVSAQQAT-AAIQSSLQRLNLDYLDLYLIHQP--YNDVF--- 118 Query: 609 NSSRIRKQTWATLVDLYHDHKIRALGVSNYFI 704 W + Y +++A+GVSN+ I Sbjct: 119 -------GAWRAMESAYRSGQLKAIGVSNFDI 143 >UniRef50_Q7NB44 Cluster: ARA1; n=3; Firmicutes|Rep: ARA1 - Mycoplasma gallisepticum Length = 289 Score = 87.8 bits (208), Expect = 7e-16 Identities = 53/151 (35%), Positives = 87/151 (57%) Frame = +3 Query: 252 LNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPK 431 L N +MP+IG T+K+ ++ V AL+ GYR D A +Y N++ ++ K Sbjct: 16 LANNYKMPSIGFGTYKLEDGKQTVEAVKTALEVGYRHLDCAEIYENQLSVSQGIK----L 71 Query: 432 YKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLDFENRN 611 + R +IFI SK+ + G + T++AFH L +L L+Y+DL L+H P I K F++ N Sbjct: 72 SGVNRKEIFITSKIWNDDKGYES-TKKAFHKILKDLDLEYLDLLLIHWP-IGK-GFKD-N 127 Query: 612 SSRIRKQTWATLVDLYHDHKIRALGVSNYFI 704 + QTW + + Y + KI+A+G+SN+ + Sbjct: 128 WQEVNAQTWKAMEEFYLEGKIKAIGLSNFLV 158 >UniRef50_Q61U89 Cluster: Putative uncharacterized protein CBG05425; n=1; Caenorhabditis briggsae|Rep: Putative uncharacterized protein CBG05425 - Caenorhabditis briggsae Length = 319 Score = 87.8 bits (208), Expect = 7e-16 Identities = 46/114 (40%), Positives = 63/114 (55%), Gaps = 1/114 (0%) Frame = +3 Query: 318 VLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPKYKLKRGDIFIISKLLPC-NYGG 494 +L VD A++ GYR FDTA Y NE L A K LLPKYKL DIF+ +K+ P N Sbjct: 79 LLHAVDKAVEVGYRSFDTAKYYENEGELGEALKILLPKYKLSTEDIFLTTKIFPVENAAS 138 Query: 495 GAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLDFENRNSSRIRKQTWATLVDL 656 G + ++ +L L +Y+DL LVH P + D ++ + RK+ W L L Sbjct: 139 GELIKKDIEESLKLLNREYLDLVLVHYPRPFTTDDKDERNKIYRKEAWLALESL 192 >UniRef50_A0JRJ6 Cluster: Aldo/keto reductase; n=2; Micrococcineae|Rep: Aldo/keto reductase - Arthrobacter sp. (strain FB24) Length = 281 Score = 87.4 bits (207), Expect = 9e-16 Identities = 57/152 (37%), Positives = 82/152 (53%) Frame = +3 Query: 243 QFTLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKL 422 Q TLNNGV++P +G F++ T + V+DAL+AGYR DTAA Y NE + A Sbjct: 11 QLTLNNGVKIPQLGFGVFQVPPEETQ-RIVEDALEAGYRHIDTAAAYRNEAGVGAA---- 65 Query: 423 LPKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLDFE 602 + + R DIFI +KL G AF N+ LG++++DLYL+H P Sbjct: 66 ISASGIPREDIFITTKLRNGEQGN---AHEAFQNSRKALGVEFVDLYLIHWP-------- 114 Query: 603 NRNSSRIRKQTWATLVDLYHDHKIRALGVSNY 698 S + + W + LY + +IRA+GVSN+ Sbjct: 115 -VPSQGLYTEAWKAMEKLYANSQIRAIGVSNF 145 >UniRef50_Q24C22 Cluster: Oxidoreductase, aldo/keto reductase family protein; n=4; Oligohymenophorea|Rep: Oxidoreductase, aldo/keto reductase family protein - Tetrahymena thermophila SB210 Length = 297 Score = 87.4 bits (207), Expect = 9e-16 Identities = 51/148 (34%), Positives = 82/148 (55%) Frame = +3 Query: 261 GVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPKYKL 440 G +P IG T+++ ++ V +ALK GY DTA++Y NE + P Y + Sbjct: 21 GGSIPQIGYGTYELRQNDCIIG-VTEALKIGYTHIDTASVYRNEQDIAKVIHN--PAYGI 77 Query: 441 KRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLDFENRNSSR 620 KR D+FI SK+ P G ++A + L+ L + Y+D L+H PG+ KL + +++ Sbjct: 78 KREDLFITSKISPGEQGYEQA-KKAVQDMLTRLNIKYLDCVLIHWPGVSKLPPNDPKNAQ 136 Query: 621 IRKQTWATLVDLYHDHKIRALGVSNYFI 704 IR +TW L++L I+ +GVSN+ I Sbjct: 137 IRLETWKALIELRKAGVIKHIGVSNFNI 164 >UniRef50_P38715 Cluster: NADPH-dependent aldose reductase GRE3; n=39; cellular organisms|Rep: NADPH-dependent aldose reductase GRE3 - Saccharomyces cerevisiae (Baker's yeast) Length = 327 Score = 87.0 bits (206), Expect = 1e-15 Identities = 48/121 (39%), Positives = 73/121 (60%), Gaps = 1/121 (0%) Frame = +3 Query: 249 TLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLP 428 TLNNG++MP +GL +K+ Q + +A+K GYR+FD A YGNE + +K + Sbjct: 6 TLNNGLKMPLVGLGCWKIDKKVCANQ-IYEAIKLGYRLFDGACDYGNEKEVGEGIRKAIS 64 Query: 429 KYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYK-LDFEN 605 + + R DIF++SKL N+ + A TLS++GLDY+DLY +H P +K + FE Sbjct: 65 EGLVSRKDIFVVSKLWN-NFHHPDHVKLALKKTLSDMGLDYLDLYYIHFPIAFKYVPFEE 123 Query: 606 R 608 + Sbjct: 124 K 124 >UniRef50_Q2LZ66 Cluster: GA19341-PA; n=2; Endopterygota|Rep: GA19341-PA - Drosophila pseudoobscura (Fruit fly) Length = 315 Score = 86.2 bits (204), Expect = 2e-15 Identities = 56/161 (34%), Positives = 83/161 (51%), Gaps = 10/161 (6%) Frame = +3 Query: 246 FTLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLL 425 F L++G MP +GL T++ V Q V DA+ GYR FD A +YGNE+++ A ++ + Sbjct: 6 FLLSSGRNMPMVGLGTWRSPP-EVVAQAVKDAIDIGYRHFDCAHIYGNELHVGVAIREKI 64 Query: 426 PKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKL---- 593 + + R ++FI SKL + + A +L NLG+DY+DLYL+H P YK Sbjct: 65 QEGLVTRDELFITSKLWN-TFHKPELVRAACETSLRNLGIDYLDLYLMHWPMAYKSGDNL 123 Query: 594 -----DFENRNSSRI-RKQTWATLVDLYHDHKIRALGVSNY 698 D I TW + DL + A+GVSN+ Sbjct: 124 YPTCPDTGKAVFEDIDYLDTWKAMEDLVDSGLVNAIGVSNF 164 >UniRef50_Q22352 Cluster: Putative uncharacterized protein T08H10.1; n=2; Caenorhabditis|Rep: Putative uncharacterized protein T08H10.1 - Caenorhabditis elegans Length = 333 Score = 86.2 bits (204), Expect = 2e-15 Identities = 57/159 (35%), Positives = 79/159 (49%), Gaps = 10/159 (6%) Frame = +3 Query: 252 LNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPK 431 LN G ++P GL T+++ + + AL AGYR+ DTA LY NE + + + Sbjct: 8 LNTGAQLPLFGLGTWQVKDEAELTVALRAALDAGYRLIDTAHLYQNEHIIGKVLHEYISS 67 Query: 432 YKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLD----- 596 KLKR DIF+ SKL P + + L L L+YIDLYL+H P +K Sbjct: 68 GKLKREDIFVTSKL-PFTAHAPEDVPKCVESQLKALQLEYIDLYLIHCPFPFKHQEGSFA 126 Query: 597 --FENRN---SSRIRKQTWATLVDLYHDHKIRALGVSNY 698 EN + TW L LY + K++ALGVSN+ Sbjct: 127 PLMENGELAVTEIAHIDTWRALEKLYKEGKLKALGVSNF 165 >UniRef50_UPI0000588153 Cluster: PREDICTED: hypothetical protein; n=1; Strongylocentrotus purpuratus|Rep: PREDICTED: hypothetical protein - Strongylocentrotus purpuratus Length = 333 Score = 85.8 bits (203), Expect = 3e-15 Identities = 57/161 (35%), Positives = 87/161 (54%), Gaps = 11/161 (6%) Frame = +3 Query: 249 TLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLP 428 TL +G MP +GL T+K+ V + A+ AGYR FD A +YGNE + A ++ + Sbjct: 6 TLPSGHAMPLVGLGTWKL-KADEVAGAIGAAVDAGYRHFDCALIYGNEKEVGVALREAMQ 64 Query: 429 KYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNP-GIYKLD--- 596 + LKR D+FI +K+ + V E F+ +L++L LDYIDLY++H P G L Sbjct: 65 RLGLKREDVFITTKVWNTFHAKEDVAE-CFNRSLTDLQLDYIDLYIMHWPLGFQNLGPTV 123 Query: 597 -FENRNSSRI------RKQTWATLVDLYHDHKIRALGVSNY 698 F + I +TW+ + DL K ++LG+SN+ Sbjct: 124 MFPRTETGDIVYSDVHYLETWSAMEDLVKTGKCKSLGLSNF 164 >UniRef50_UPI000065D0BD Cluster: Homolog of Homo sapiens "AKR1B1 protein.; n=1; Takifugu rubripes|Rep: Homolog of Homo sapiens "AKR1B1 protein. - Takifugu rubripes Length = 330 Score = 85.8 bits (203), Expect = 3e-15 Identities = 46/110 (41%), Positives = 66/110 (60%) Frame = +3 Query: 249 TLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLP 428 TLN G MP +GL T+K G T + V A+ AGYR DTA +Y NE + + ++ Sbjct: 6 TLNTGALMPVLGLGTWKSGKGVTT-EAVKVAIGAGYRHIDTAYVYENETEVGAGVQAMID 64 Query: 429 KYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNP 578 + +KR ++FI+SKL C + ++ A TLS+L LDY+DLYL+H P Sbjct: 65 QGVVKREELFIVSKLW-CTFHTPSLVRGACEKTLSSLNLDYVDLYLMHFP 113 >UniRef50_P22045 Cluster: Probable reductase; n=101; cellular organisms|Rep: Probable reductase - Leishmania major Length = 284 Score = 85.8 bits (203), Expect = 3e-15 Identities = 57/152 (37%), Positives = 79/152 (51%) Frame = +3 Query: 249 TLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLP 428 TL+NGV+MP GL ++ V+ AL AGYR DTAA+Y NE + L Sbjct: 10 TLSNGVKMPQFGLGVWQSPAGEVTENAVNWALCAGYRHIDTAAIYKNEESVGAG----LR 65 Query: 429 KYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLDFENR 608 + R D+FI +KL G + T AF + LG+DYIDLYL+H P D ++ Sbjct: 66 ASGVPREDVFITTKLWNTEQGYES-TLAAFEESRQKLGVDYIDLYLIHWP--RGKDILSK 122 Query: 609 NSSRIRKQTWATLVDLYHDHKIRALGVSNYFI 704 + +W LY + K+RA+GVSN+ I Sbjct: 123 EGKKY-LDSWRAFEQLYKEKKVRAIGVSNFHI 153 >UniRef50_Q02198 Cluster: Morphine 6-dehydrogenase; n=5; Bacteria|Rep: Morphine 6-dehydrogenase - Pseudomonas putida Length = 296 Score = 85.8 bits (203), Expect = 3e-15 Identities = 53/149 (35%), Positives = 79/149 (53%) Frame = +3 Query: 252 LNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPK 431 LNNGV+MPA+GL F T + A+ +GYR+ DTA Y NE + + Sbjct: 10 LNNGVKMPALGLGVFAASAEETA-SAIASAISSGYRLIDTARSYNNEAQVGEGIRNS--- 65 Query: 432 YKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLDFENRN 611 + R ++F+ +KL C+YG RAF +L LGLDY+DLYL+H P ++ N Sbjct: 66 -GVDRAEMFVTTKLFNCDYGYERAL-RAFDESLGRLGLDYVDLYLLHWP------TKDWN 117 Query: 612 SSRIRKQTWATLVDLYHDHKIRALGVSNY 698 ++ Q+W + D + RA+GV N+ Sbjct: 118 AT---IQSWKAAEKILGDGRARAIGVCNF 143 >UniRef50_Q55FL3 Cluster: Aldo-keto reductase; n=2; Dictyostelium discoideum AX4|Rep: Aldo-keto reductase - Dictyostelium discoideum AX4 Length = 321 Score = 85.0 bits (201), Expect = 5e-15 Identities = 54/165 (32%), Positives = 89/165 (53%), Gaps = 14/165 (8%) Frame = +3 Query: 246 FTLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLL 425 F LN+G ++P+IGL T+ + V +++ALK GYR D AA YGNE + + K++ Sbjct: 17 FKLNDGNQIPSIGLGTYYSENPGEVGDAINNALKNGYRHIDGAAFYGNEKVIGNSLKEIF 76 Query: 426 PKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVH--------NP- 578 + ++KR DIF SKL + V + T+ +LG+ Y+DLYL+H NP Sbjct: 77 KEGEIKREDIFYTSKLWNSCHNSNLVVKHCV-KTIEDLGIGYLDLYLIHWPIAFENSNPL 135 Query: 579 GIYKLDFENRNSSRIR-----KQTWATLVDLYHDHKIRALGVSNY 698 G+ ++N + I ++TW + L ++++GVSN+ Sbjct: 136 GLTIEPLRDQNGNPIIAPVSIRETWQEMEKLVELGLVKSIGVSNF 180 >UniRef50_Q7VG53 Cluster: Aldo-keto reductase; n=28; Bacteria|Rep: Aldo-keto reductase - Helicobacter hepaticus Length = 292 Score = 84.6 bits (200), Expect = 6e-15 Identities = 54/156 (34%), Positives = 83/156 (53%) Frame = +3 Query: 231 ILPQQFTLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFA 410 IL + FTLNNG ++P +GL T+++ V V +A K GYR DTA YGNE + A Sbjct: 10 ILNEFFTLNNGNKIPKLGLGTWRIDD-NVVEAAVREAFKVGYRHIDTAQAYGNERGVGEA 68 Query: 411 FKKLLPKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYK 590 + K K+KR ++FI SK + Y + +L + LD+IDL L+H+P + Sbjct: 69 VR----KSKIKREELFITSK-IRAEYKDYKSASASIDTSLKTMKLDFIDLMLIHSPQPWN 123 Query: 591 LDFENRNSSRIRKQTWATLVDLYHDHKIRALGVSNY 698 F + + + + L D K+R++GVSN+ Sbjct: 124 -SFRKGDYFKENVEVYNALEDAQKAGKVRSIGVSNF 158 >UniRef50_P38115 Cluster: D-arabinose dehydrogenase [NAD(P)+] heavy chain; n=3; Saccharomycetaceae|Rep: D-arabinose dehydrogenase [NAD(P)+] heavy chain - Saccharomyces cerevisiae (Baker's yeast) Length = 344 Score = 84.6 bits (200), Expect = 6e-15 Identities = 60/175 (34%), Positives = 90/175 (51%), Gaps = 22/175 (12%) Frame = +3 Query: 246 FTLNNGVEMPAIGLDTFKMGH-FYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKL 422 F+LNNGV +PA+GL T Q V A+KAGYR DTA Y E ++ A K+L Sbjct: 25 FSLNNGVRIPALGLGTANPHEKLAETKQAVKAAIKAGYRHIDTAWAYETEPFVGEAIKEL 84 Query: 423 LPKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNP-------- 578 L +KR D+FI +K+ P + +R+ + +L LGL+Y+DL L H P Sbjct: 85 LEDGSIKREDLFITTKVWPVLWD---EVDRSLNESLKALGLEYVDLLLQHWPLCFEKIKD 141 Query: 579 -----GIYKLDFENRNSSRIRK-----QTWATLVDLY---HDHKIRALGVSNYFI 704 G+ K ++ + +T+ L +Y +DH++RA+GVSN+ I Sbjct: 142 PKGISGLVKTPVDDSGKTMYAADGDYLETYKQLEKIYLDPNDHRVRAIGVSNFSI 196 >UniRef50_Q8WRT0 Cluster: 3-dehydrecdysone 3b-reductase; n=1; Trichoplusia ni|Rep: 3-dehydrecdysone 3b-reductase - Trichoplusia ni (Cabbage looper) Length = 308 Score = 84.2 bits (199), Expect = 8e-15 Identities = 53/150 (35%), Positives = 81/150 (54%), Gaps = 1/150 (0%) Frame = +3 Query: 252 LNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPK 431 LN+G +P++ L TF G V Q V A++AGYR DTAALYGNE + + + Sbjct: 29 LNDGNAIPSLALGTFGFGDIPKVRQAVLWAIQAGYRHIDTAALYGNEEEVGKGIADAIQQ 88 Query: 432 YKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLDFENRN 611 +KR ++F+ +KL +G V A +L+ LGL Y+DLYL+H+P + EN + Sbjct: 89 GLVKREELFVTTKLWNDKHGRHQVVP-ALRESLTKLGLSYVDLYLIHSP---EATNENGD 144 Query: 612 SSRIR-KQTWATLVDLYHDHKIRALGVSNY 698 I TW + + +++GVSN+ Sbjct: 145 PVDIDVLNTWNGMEEAKKLGLAKSIGVSNF 174 >UniRef50_Q54B70 Cluster: Aldehyde reductase; n=2; Dictyostelium discoideum|Rep: Aldehyde reductase - Dictyostelium discoideum AX4 Length = 297 Score = 84.2 bits (199), Expect = 8e-15 Identities = 58/162 (35%), Positives = 89/162 (54%), Gaps = 7/162 (4%) Frame = +3 Query: 246 FTLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAF-KKL 422 F L++G ++P +G T+K V + V+ AL AGYR D AA+Y NE + AF KK Sbjct: 5 FKLSSGHKIPLVGFGTWK-AETTLVGKAVEVALDAGYRHIDCAAVYLNEKEVGEAFTKKF 63 Query: 423 LPKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKL--- 593 + +KR D+FI SKL + V A TLS+LGL Y+DLYLVH P ++ Sbjct: 64 TTEATVKREDVFITSKLWNTFHKKEHVRP-ALERTLSDLGLQYLDLYLVHWPVAFEYTSN 122 Query: 594 DFENRNSSR---IRKQTWATLVDLYHDHKIRALGVSNYFIWG 710 D + S++ ++TW + L ++++G+SN+ + G Sbjct: 123 DIQTSGSTQEFVSIRETWEEMEKLVDAGLVKSIGLSNFNVQG 164 >UniRef50_Q9VTL0 Cluster: CG6083-PA; n=4; Diptera|Rep: CG6083-PA - Drosophila melanogaster (Fruit fly) Length = 322 Score = 83.8 bits (198), Expect = 1e-14 Identities = 54/162 (33%), Positives = 84/162 (51%), Gaps = 11/162 (6%) Frame = +3 Query: 246 FTLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLL 425 F L+NG MP +GL T++ V Q V DA+ GYR FD A +YGNE + A ++ + Sbjct: 6 FLLSNGKNMPMLGLGTWRSPP-EVVTQAVKDAIDIGYRHFDCAHIYGNEAQVGAALREKM 64 Query: 426 PKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLDFEN 605 + + R ++FI SKL ++ V A ++ NLG+ Y++LYL+H P YK +N Sbjct: 65 DEGVVTRDELFITSKLWNTHHKPDLV-RPACETSIRNLGVKYLNLYLMHWPMAYKSGSDN 123 Query: 606 -------RNSSRIRK----QTWATLVDLYHDHKIRALGVSNY 698 N + TW + +L + +A+GVSN+ Sbjct: 124 LYPTCPDTNKAAFEDIDYVDTWRAMENLVDEGLCQAIGVSNF 165 >UniRef50_A5E082 Cluster: GCY protein; n=4; Saccharomycetales|Rep: GCY protein - Lodderomyces elongisporus (Yeast) (Saccharomyces elongisporus) Length = 295 Score = 83.8 bits (198), Expect = 1e-14 Identities = 53/152 (34%), Positives = 78/152 (51%), Gaps = 1/152 (0%) Frame = +3 Query: 246 FTLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLL 425 +TLNNG+++PAIGL T+ + ALK GY+ DTAA YGNE + + + Sbjct: 12 YTLNNGLKIPAIGLGTWLADEEDAAYKATLTALKNGYKHIDTAAAYGNEDQVG----RAI 67 Query: 426 PKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLDFEN 605 + R +IF+ +KL + E A +L LGL+Y+DLYL+H P E Sbjct: 68 ADSGVSRDEIFVTTKLWNDQHKD---PEGALDESLKKLGLEYVDLYLIHWPLSVDPKTEK 124 Query: 606 RNSSRIRKQTWATLVDLYHD-HKIRALGVSNY 698 TW L +Y + K++A+GVSN+ Sbjct: 125 PYDDYDFVDTWRNLQKIYKEGKKVKAIGVSNF 156 >UniRef50_A3LTU8 Cluster: D-arabinose dehydrogenase; n=5; Saccharomycetales|Rep: D-arabinose dehydrogenase - Pichia stipitis (Yeast) Length = 326 Score = 83.8 bits (198), Expect = 1e-14 Identities = 59/172 (34%), Positives = 90/172 (52%), Gaps = 19/172 (11%) Frame = +3 Query: 246 FTLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLL 425 F L+NG +PA+GL T + + + V A+KAGYR DTA YG E Y+ A K+L Sbjct: 10 FVLSNGKTIPALGLGTVPPEDPHELKEQVITAVKAGYRHIDTAWYYGTEEYIGQALKQLF 69 Query: 426 PKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLDFEN 605 + +KR D+FI +K+ P + E++ +L++LGLDY+DL+L H P + D EN Sbjct: 70 EEGIVKREDLFITTKVWPSFWRN---PEKSLDKSLADLGLDYVDLFLQHWPVVLHGD-EN 125 Query: 606 RNSSRIRKQTWATL-----------VDLYHD--------HKIRALGVSNYFI 704 + R + + +D YH K++++GVSNY I Sbjct: 126 GLPPQPRDKDGKLIYDDDPVSGIKYIDAYHSLEDIMDNTSKVKSIGVSNYSI 177 >UniRef50_UPI00006CA3CB Cluster: oxidoreductase, aldo/keto reductase family protein; n=3; Tetrahymena thermophila SB210|Rep: oxidoreductase, aldo/keto reductase family protein - Tetrahymena thermophila SB210 Length = 299 Score = 83.4 bits (197), Expect = 1e-14 Identities = 50/151 (33%), Positives = 75/151 (49%), Gaps = 1/151 (0%) Frame = +3 Query: 249 TLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLP 428 TL+NG +MPA GL + ++ V + AL GYR DTA +Y NE ++ A K + Sbjct: 11 TLSNGQKMPAFGLGSSRVQSVEEVTNLIRKALDVGYRHIDTAQMYENEQFIGAALKTIFG 70 Query: 429 KYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNP-GIYKLDFEN 605 + K KR DIF+++K G L L +DY+DL L+H P D++ Sbjct: 71 EGKYKREDIFLVTKQASIK---GVSCLEIMKEQLQKLQVDYVDLLLIHVPLAAPSDDYQQ 127 Query: 606 RNSSRIRKQTWATLVDLYHDHKIRALGVSNY 698 N + Q WA +++ + LGVSN+ Sbjct: 128 WNHKPVH-QIWAEFEEIHSLGLAKGLGVSNF 157 >UniRef50_Q568D7 Cluster: Zgc:110366; n=7; Euteleostomi|Rep: Zgc:110366 - Danio rerio (Zebrafish) (Brachydanio rerio) Length = 289 Score = 83.4 bits (197), Expect = 1e-14 Identities = 52/151 (34%), Positives = 85/151 (56%) Frame = +3 Query: 252 LNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPK 431 L+NG+ +P +GL T G Y+ + + G R DTA YG E L K + + Sbjct: 18 LHNGLNIPILGLGTSHYGG-YSHEAVLYALQECGIRHIDTAKRYGCEEALG----KAVTE 72 Query: 432 YKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLDFENRN 611 ++R ++++ +KL P +YG + T++A ++ + LG+DY+DLYL+H P R+ Sbjct: 73 SGVQREELWVTTKLWPGDYGYQS-TKQACRDSRARLGVDYLDLYLMHWPDSM---VPGRS 128 Query: 612 SSRIRKQTWATLVDLYHDHKIRALGVSNYFI 704 S +R +TW L +LY + RA+GVSN+ I Sbjct: 129 SQEVRLETWRALEELYDEGLCRAIGVSNFLI 159 >UniRef50_A3JU52 Cluster: 2,5-diketo-D-gluconic acid reductase A; n=1; Rhodobacterales bacterium HTCC2150|Rep: 2,5-diketo-D-gluconic acid reductase A - Rhodobacterales bacterium HTCC2150 Length = 334 Score = 83.4 bits (197), Expect = 1e-14 Identities = 56/157 (35%), Positives = 82/157 (52%), Gaps = 6/157 (3%) Frame = +3 Query: 246 FTLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLL 425 FTLN +PA+G T+ + + T+ A++AGYR DTA+ Y NE + K L Sbjct: 40 FTLNTTTTIPAVGFGTYLISND-DAKSTISAAIQAGYRHIDTASGYQNEKTVGAGIKAGL 98 Query: 426 PKYKLKRGDIFIISKLLPCNYGGG------AVTERAFHNTLSNLGLDYIDLYLVHNPGIY 587 + R D+F+ +KL P N G A T +L+ LGLDY+DLYL+H P Y Sbjct: 99 QSAGITRKDLFVTAKLWPGNPAWGDAPKTKAQTLDECDASLARLGLDYVDLYLIHAP--Y 156 Query: 588 KLDFENRNSSRIRKQTWATLVDLYHDHKIRALGVSNY 698 D +R + W L++L + K R++GVSN+ Sbjct: 157 GGD--------MRLEQWRALLELQANGKARSIGVSNF 185 >UniRef50_Q2UGR1 Cluster: Aldo/keto reductase family proteins; n=2; Ascomycota|Rep: Aldo/keto reductase family proteins - Aspergillus oryzae Length = 323 Score = 83.4 bits (197), Expect = 1e-14 Identities = 62/166 (37%), Positives = 86/166 (51%), Gaps = 11/166 (6%) Frame = +3 Query: 234 LPQQFTLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAF 413 L + F LN+G +PAIGL T+ + + V V+ AL+AGYR D AA Y NE + + Sbjct: 3 LGRTFKLNSGYNIPAIGLGTW-LSKPHEVENAVEAALRAGYRHIDAAACYQNENEVGNGW 61 Query: 414 KKLLPKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKL 593 KK + R IFI SKL ++ V E A + TL +L DY+DLYL+H P ++ Sbjct: 62 KKS----GVPRDQIFITSKLWNTHHHPEHV-EEAVNKTLKDLQTDYLDLYLIHWPVAFEH 116 Query: 594 DFENRN-----SSRIR------KQTWATLVDLYHDHKIRALGVSNY 698 E + R R TWA L L KIR++G+SN+ Sbjct: 117 TNETLTPIDPVTKRFRLANVPIADTWAALEKLVEAKKIRSIGISNF 162 >UniRef50_A7PNI3 Cluster: Chromosome chr1 scaffold_22, whole genome shotgun sequence; n=2; Vitis vinifera|Rep: Chromosome chr1 scaffold_22, whole genome shotgun sequence - Vitis vinifera (Grape) Length = 360 Score = 82.6 bits (195), Expect = 2e-14 Identities = 58/161 (36%), Positives = 79/161 (49%), Gaps = 10/161 (6%) Frame = +3 Query: 246 FTLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLL 425 F LN ++PAIGL T++ G V + V AL GYR D A LYGNEV + A + Sbjct: 12 FLLNTKAKIPAIGLGTWQSGGDLCV-EAVKRALSEGYRQIDCAHLYGNEVEVGEALAEAF 70 Query: 426 PKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKL---- 593 LKR D+F+ SKL C E + +L NLG+ Y+DLYL+H P I Sbjct: 71 -NGSLKREDVFLTSKLY-CTMNSLNKIENSVRVSLKNLGVTYLDLYLMHWPDITAFGDAT 128 Query: 594 ------DFENRNSSRIRKQTWATLVDLYHDHKIRALGVSNY 698 ++R K+ W + L +RA+GVSN+ Sbjct: 129 DPPSNSGNDHRQFLNRLKKAWKAMEGLIELGLVRAIGVSNF 169 >UniRef50_Q0IBY6 Cluster: Alcohol dehydrogenase; n=2; Chroococcales|Rep: Alcohol dehydrogenase - Synechococcus sp. (strain CC9311) Length = 336 Score = 82.2 bits (194), Expect = 3e-14 Identities = 46/122 (37%), Positives = 73/122 (59%), Gaps = 2/122 (1%) Frame = +3 Query: 219 DFKYILP--QQFTLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNE 392 + K ++P Q +L+NG MP +GL T K V ++V +A+K GYR D A++YGNE Sbjct: 11 NIKDVIPTMQYASLSNGDRMPLLGLGTGK-SESRQVYKSVREAIKIGYRHIDCASIYGNE 69 Query: 393 VYLNFAFKKLLPKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVH 572 + A + + +++ R +++I SKL +G V E A +L NLG+DY++LYL+H Sbjct: 70 EEVGDAIRDAIQNHEITRSELWITSKLWSNCHGKNHV-EAALSQSLQNLGVDYLNLYLIH 128 Query: 573 NP 578 P Sbjct: 129 WP 130 >UniRef50_Q6TY50 Cluster: Reductase 2; n=10; Magnoliophyta|Rep: Reductase 2 - Hydrangea macrophylla (Bigleaf hydrangea) Length = 321 Score = 82.2 bits (194), Expect = 3e-14 Identities = 58/166 (34%), Positives = 86/166 (51%), Gaps = 9/166 (5%) Frame = +3 Query: 228 YILPQQFTLNNGVEMPAIGLDTFKMGHF--YTVLQTVDDALKAGYRMFDTAALYGNEVYL 401 + +P+ + G +MP +GL T TV + V +ALK GYR FDTAALY +E L Sbjct: 3 FTIPEVPLSSGGRKMPVLGLGTAADPPVDPETVRKAVTEALKLGYRHFDTAALYNSEQPL 62 Query: 402 NFAFKKLLPKYKLK-RGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVH-- 572 A + L + +K R ++FI SKL C+ E A TL NL L+YID+YL+H Sbjct: 63 GDAIAEALGEGLIKSRDELFITSKLW-CSDAHRENVEPALQKTLKNLKLEYIDMYLIHWP 121 Query: 573 ---NPGIYKLDFENRNSSRI-RKQTWATLVDLYHDHKIRALGVSNY 698 PG Y+ + + ++ K W + + +A+GVSN+ Sbjct: 122 VSSKPGNYEYPIKKEDFLQMDYKSVWEAMEECQKLGLTKAIGVSNF 167 >UniRef50_Q7PM68 Cluster: ENSANGP00000014386; n=1; Anopheles gambiae str. PEST|Rep: ENSANGP00000014386 - Anopheles gambiae str. PEST Length = 310 Score = 82.2 bits (194), Expect = 3e-14 Identities = 53/157 (33%), Positives = 81/157 (51%), Gaps = 10/157 (6%) Frame = +3 Query: 258 NGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFK-KLLPKY 434 + + +P IGL T+ + + + A+ GYRMFDTA YGNE + A + K+ Sbjct: 13 HSIALPTIGLGTYSILGA-DGKEAIRTAIDVGYRMFDTAVAYGNEAIVGEAIREKIRECN 71 Query: 435 KLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLDFE-NRN 611 L R D FIISKL +Y + E+ TL LG+DY+DLYL+H P + + + RN Sbjct: 72 NLTRDDFFIISKLSG-SYHRQDLVEKCCRMTLDRLGMDYVDLYLMHTPVALQSEKKCARN 130 Query: 612 SSRIR--------KQTWATLVDLYHDHKIRALGVSNY 698 +++ + W L Y + R++GVSN+ Sbjct: 131 GTKLNAIDDSIAPTEAWIGLEQCYQEGLCRSIGVSNF 167 >UniRef50_Q8SSK6 Cluster: ALDOSE REDUCTASE; n=1; Encephalitozoon cuniculi|Rep: ALDOSE REDUCTASE - Encephalitozoon cuniculi Length = 301 Score = 81.8 bits (193), Expect = 4e-14 Identities = 44/109 (40%), Positives = 63/109 (57%) Frame = +3 Query: 252 LNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPK 431 LNNG E+P +GL T+ M + + +AL GYR DTA +YGNE + KKL + Sbjct: 8 LNNGKEIPTVGLGTWGMEDEAVLEGAIRNALSLGYRHIDTAFIYGNEKMIGNILKKLFDE 67 Query: 432 YKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNP 578 ++R D+FI SKL +G E +L++L +DY+DLYL+H P Sbjct: 68 GVVQRKDLFITSKLWNTFHG---CPEDGLRRSLNDLQMDYVDLYLIHWP 113 >UniRef50_Q6NII7 Cluster: Putative oxidoreductase; n=2; Corynebacterium|Rep: Putative oxidoreductase - Corynebacterium diphtheriae Length = 290 Score = 81.4 bits (192), Expect = 6e-14 Identities = 46/116 (39%), Positives = 68/116 (58%) Frame = +3 Query: 231 ILPQQFTLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFA 410 I+P TLN+G EMPAIG T+K+ + V A++ GYR DTA+LY NE + A Sbjct: 10 IIPT-ITLNDGTEMPAIGFGTYKLRE-QDAYRAVRSAIEVGYRHIDTASLYKNEEEVGRA 67 Query: 411 FKKLLPKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNP 578 + ++ R ++FI +K+ + G +T+R+F +L LGLDYID +VH P Sbjct: 68 VADAITAGEVARDELFITTKVWN-DMHGDQLTQRSFQESLHRLGLDYIDCCMVHWP 122 >UniRef50_Q1RFP0 Cluster: 2,5-diketo-D-gluconic acid reductase A; n=21; Bacteria|Rep: 2,5-diketo-D-gluconic acid reductase A - Escherichia coli (strain UTI89 / UPEC) Length = 294 Score = 81.4 bits (192), Expect = 6e-14 Identities = 47/150 (31%), Positives = 78/150 (52%) Frame = +3 Query: 252 LNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPK 431 L+N ++MP +G F++ Q+V +A++ GYR+ DTAA+YGNE + A ++ + + Sbjct: 11 LSNNLKMPMMGFGVFQVTDKDVCKQSVLNAIRTGYRLIDTAAVYGNEDAVGEAVREAISE 70 Query: 432 YKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLDFENRN 611 R ++FI SKL + + +L GL+Y DLYL+H Sbjct: 71 GLCTREELFITSKLWVQDMLNQDIAAAGIEASLKKSGLEYFDLYLLH------------Q 118 Query: 612 SSRIRKQTWATLVDLYHDHKIRALGVSNYF 701 + R W L D Y + K++A+GVSN++ Sbjct: 119 AMRDYFSAWRALEDAYEEGKLKAIGVSNFY 148 >UniRef50_Q9ZBW7 Cluster: Putative oxidoreductase; n=2; Actinomycetales|Rep: Putative oxidoreductase - Streptomyces coelicolor Length = 277 Score = 81.0 bits (191), Expect = 8e-14 Identities = 56/149 (37%), Positives = 81/149 (54%) Frame = +3 Query: 252 LNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPK 431 LNNGVEMP +G +++ V AL+AGYR DTAA+YGNE A + Sbjct: 10 LNNGVEMPQLGFGVWQVPDD-DAQTAVALALEAGYRSIDTAAIYGNEEGTGRA----IAA 64 Query: 432 YKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLDFENRN 611 L R D+F+ +KL + G + T RAF +++ LGL+Y+DLYL+H P K + + Sbjct: 65 SGLAREDLFVTTKLWNSDQGYDS-TLRAFDTSMAKLGLEYLDLYLIHWPMPAKERYVD-- 121 Query: 612 SSRIRKQTWATLVDLYHDHKIRALGVSNY 698 T+ L D ++RA+GVSN+ Sbjct: 122 -------TYKAFEKLLADGRVRAIGVSNF 143 >UniRef50_Q927E1 Cluster: Lin2848 protein; n=13; Listeria|Rep: Lin2848 protein - Listeria innocua Length = 280 Score = 81.0 bits (191), Expect = 8e-14 Identities = 54/151 (35%), Positives = 76/151 (50%) Frame = +3 Query: 246 FTLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLL 425 + LNNG+EMP G +K+ + ++ A+ GYR+FDTA+ Y NE L F Sbjct: 9 YRLNNGIEMPRHGFGVYKLTDEQRMRTALETAVDVGYRLFDTASFYHNEKELGDFF---- 64 Query: 426 PKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLDFEN 605 LKR + F+ +K+ G T RAF + L LD +DLYLVH P K D Sbjct: 65 ASSGLKRDEFFVTTKMWNTEQGYDE-TLRAFEKSQKKLQLDQVDLYLVHWP---KQD--- 117 Query: 606 RNSSRIRKQTWATLVDLYHDHKIRALGVSNY 698 +TW + LY + +RA+GVSN+ Sbjct: 118 -----TFFETWRAVEKLYDEGLVRAIGVSNF 143 >UniRef50_A5KSS3 Cluster: Aldehyde reductase; n=1; candidate division TM7 genomosp. GTL1|Rep: Aldehyde reductase - candidate division TM7 genomosp. GTL1 Length = 299 Score = 81.0 bits (191), Expect = 8e-14 Identities = 51/159 (32%), Positives = 85/159 (53%), Gaps = 9/159 (5%) Frame = +3 Query: 249 TLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLP 428 TL N +P +G T+++ T V+ A+KAGYR D A +YGNE + ++ + Sbjct: 5 TLRNKQTLPLLGYGTWELPTG-TTADLVETAIKAGYRHIDCAMIYGNEKEVGEGIRRTID 63 Query: 429 KYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLV-------HNPGIY 587 + +KR D+F+ SKL ++ V A TL++LGLDY+DLYL+ H + Sbjct: 64 QGVVKREDLFVTSKLWNTDHAQVDVGV-ACRKTLNDLGLDYLDLYLIHWGVAFEHGDNLE 122 Query: 588 KLDFEN--RNSSRIRKQTWATLVDLYHDHKIRALGVSNY 698 LD + + S K+TW + +L ++++GV+N+ Sbjct: 123 PLDDDGVAKFSFISMKETWQAMEELVEQGLVKSMGVANF 161 >UniRef50_Q7ZA52 Cluster: Aldose reductase; n=6; Pezizomycotina|Rep: Aldose reductase - Magnaporthe grisea (Rice blast fungus) (Pyricularia grisea) Length = 312 Score = 81.0 bits (191), Expect = 8e-14 Identities = 58/165 (35%), Positives = 85/165 (51%), Gaps = 12/165 (7%) Frame = +3 Query: 240 QQFTLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKK 419 + FTLN G ++PA GL T++ G + + V A+K+GYR+ D A +YGNE + ++ Sbjct: 4 KDFTLNTGAKIPAFGLGTWQ-GDKGVIKEAVLTAIKSGYRLIDGAYVYGNEEEVGQGIRE 62 Query: 420 LLPKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVH-----NPGI 584 + +KR D+F++SK C E +L LGLDY+DLYLVH NP Sbjct: 63 AISSGIVKREDLFVVSK---CWATYTTRCELGLDQSLKLLGLDYVDLYLVHWPILMNPEG 119 Query: 585 YKLDF-ENRNSSR------IRKQTWATLVDLYHDHKIRALGVSNY 698 F ++ + SR TW + L K +A+GVSNY Sbjct: 120 NDEKFPKHADGSRDIIHTHNHVDTWKLMEKLPATGKTKAVGVSNY 164 >UniRef50_A6RKL9 Cluster: Putative uncharacterized protein; n=3; Sclerotiniaceae|Rep: Putative uncharacterized protein - Botryotinia fuckeliana B05.10 Length = 360 Score = 81.0 bits (191), Expect = 8e-14 Identities = 48/147 (32%), Positives = 81/147 (55%), Gaps = 2/147 (1%) Frame = +3 Query: 264 VEMPAIGLDTFKMGHF-YTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPKYKL 440 + P IG T+ + + V A++ GYR D AA+YGNEV + ++ L + L Sbjct: 37 ISQPLIGFGTWNLKVSPENTTEAVAYAIEIGYRQIDCAAVYGNEVAVGRGIEEGLKRAGL 96 Query: 441 KRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLDFENRNSSR 620 KR DI++ SKL ++G E+ + TL +LGL+Y+DLYL+H P + F + + Sbjct: 97 KREDIWVTSKLWNDHHGSYENVEKGLNQTLQDLGLEYLDLYLIHWP----IGFSSNGAKN 152 Query: 621 I-RKQTWATLVDLYHDHKIRALGVSNY 698 + QT+ +++ L ++ +GVSN+ Sbjct: 153 LDHVQTYKSMISL-PKSRVLNIGVSNF 178 >UniRef50_A7CWF9 Cluster: Aldehyde reductase; n=2; Bacteria|Rep: Aldehyde reductase - Opitutaceae bacterium TAV2 Length = 347 Score = 80.6 bits (190), Expect = 1e-13 Identities = 49/118 (41%), Positives = 69/118 (58%), Gaps = 3/118 (2%) Frame = +3 Query: 234 LPQQFTLNNGVEMPAIGLDTFKMGHFYT--VLQTVDDALKAGYRMFDTAALYGNEVYLNF 407 +PQ+ TL +G MPAIG+ TF H V +V A + GYR FD AA+Y NE + Sbjct: 16 IPQR-TLASGARMPAIGMGTFGSDHAAPGEVAASVYAAAELGYRHFDCAAVYSNEREIGA 74 Query: 408 AFKKLLPKYK-LKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNP 578 F+++L ++R D++I SKL + V AF +L +LGLDY+DLYL+H P Sbjct: 75 TFRRILTSNTGIRREDLWITSKLWNDKHAEADVIP-AFEKSLRDLGLDYLDLYLIHWP 131 >UniRef50_A4FEB9 Cluster: 2,5-diketo-D-gluconic acid reductase; n=1; Saccharopolyspora erythraea NRRL 2338|Rep: 2,5-diketo-D-gluconic acid reductase - Saccharopolyspora erythraea (strain NRRL 23338) Length = 159 Score = 80.6 bits (190), Expect = 1e-13 Identities = 49/110 (44%), Positives = 63/110 (57%) Frame = +3 Query: 249 TLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLP 428 TLNNGVEMP +G F++ T V AL+AGYR DTAA YGNE A + L Sbjct: 8 TLNNGVEMPQLGYGVFQVPEDETAA-AVGAALEAGYRSIDTAAAYGNEA----AVGRALA 62 Query: 429 KYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNP 578 L R ++F+ +KL + G RAF +L LGLD++DLYL+H P Sbjct: 63 GSGLARDELFVTTKLWNADQGYDNAL-RAFDTSLELLGLDHLDLYLIHWP 111 >UniRef50_A1D4E3 Cluster: D-xylose reductase (Xyl1), putative; n=5; Pezizomycotina|Rep: D-xylose reductase (Xyl1), putative - Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / NRRL 181)(Aspergillus fischerianus (strain ATCC 1020 / DSM 3700 / NRRL 181)) Length = 321 Score = 80.6 bits (190), Expect = 1e-13 Identities = 56/163 (34%), Positives = 84/163 (51%), Gaps = 14/163 (8%) Frame = +3 Query: 252 LNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPK 431 LN+G +MP +G +K+ + T + A+KAGYR+FD A YGNEV + + + Sbjct: 8 LNSGYDMPLVGFGLWKVNN-ETCADQIYHAIKAGYRLFDGACDYGNEVEAGKGVARAIQE 66 Query: 432 YKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYK-LD---- 596 +KR D+FI+SKL + G V E L++ GLDY DL++VH P K +D Sbjct: 67 GIVKREDLFIVSKLWNSFHDGDRV-EPICRKQLADWGLDYFDLFIVHFPIALKYVDPAVR 125 Query: 597 ------FENRN---SSRIRKQTWATLVDLYHDHKIRALGVSNY 698 EN S+ ++TW + L R++GVSN+ Sbjct: 126 YPPGWLSENNKLEFSNASIQETWTAMESLVDKKLARSIGVSNF 168 >UniRef50_Q235V6 Cluster: Oxidoreductase, aldo/keto reductase family protein; n=2; Tetrahymena thermophila SB210|Rep: Oxidoreductase, aldo/keto reductase family protein - Tetrahymena thermophila SB210 Length = 332 Score = 80.2 bits (189), Expect = 1e-13 Identities = 50/149 (33%), Positives = 76/149 (51%) Frame = +3 Query: 252 LNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPK 431 LNNG MP +GL T+ + + + AL AGYR DTA Y NE + + K + + Sbjct: 10 LNNGQIMPLVGLGTYLLNSKEEMTNLLRTALDAGYRHIDTAVNYQNEAMIGESLKTIFKE 69 Query: 432 YKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLDFENRN 611 K R D+FI+SK+ P N G + + +L L LDY+DLY +H P + + E Sbjct: 70 GKYSRKDLFIVSKVFP-NKGINML--ESVKKSLKELQLDYVDLYYLHFPLGFLSEKEEFV 126 Query: 612 SSRIRKQTWATLVDLYHDHKIRALGVSNY 698 + WA L + + +++GVSN+ Sbjct: 127 HLPVH-VAWAQLEEAHRLGLAKSIGVSNF 154 >UniRef50_Q4P4P1 Cluster: Putative uncharacterized protein; n=1; Ustilago maydis|Rep: Putative uncharacterized protein - Ustilago maydis (Smut fungus) Length = 322 Score = 80.2 bits (189), Expect = 1e-13 Identities = 50/156 (32%), Positives = 77/156 (49%) Frame = +3 Query: 231 ILPQQFTLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFA 410 I Q+ LNNG E+P + L +K + + A AGYR D+AA Y NE + A Sbjct: 14 ISTQRIKLNNGQEIPQVALGVYKAPNDGSTENACKWAFDAGYRHIDSAARYMNEESVGRA 73 Query: 411 FKKLLPKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYK 590 + + + R +IFI SKL ++ A A ++L L +DY+D+YL+H+PG Sbjct: 74 LAEWTKENNVPRSEIFITSKLWDADHDKAAA---AIEDSLKKLNVDYMDMYLMHSPGTM- 129 Query: 591 LDFENRNSSRIRKQTWATLVDLYHDHKIRALGVSNY 698 + R + W L + KI+ +GVSN+ Sbjct: 130 -------GAEKRLEAWKALEEAVDAGKIKTIGVSNF 158 >UniRef50_Q890A0 Cluster: Oxidoreductase; n=6; Lactobacillales|Rep: Oxidoreductase - Lactobacillus plantarum Length = 282 Score = 79.8 bits (188), Expect = 2e-13 Identities = 51/158 (32%), Positives = 73/158 (46%) Frame = +3 Query: 231 ILPQQFTLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFA 410 +L + L NGV +P + T+++ Q V AL AGYR DTA Y NE + A Sbjct: 3 VLTTMYQLANGVNIPKVAFGTWQIPGGEATYQAVRAALAAGYRHIDTALAYQNEASVGQA 62 Query: 411 FKKLLPKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYK 590 + + R IF+ +K LP F +L NLGLDY+DLYLVH P + Sbjct: 63 IR----DSGIPREQIFVTTK-LPAETKSYQGALNDFDRSLKNLGLDYVDLYLVHAP--WP 115 Query: 591 LDFENRNSSRIRKQTWATLVDLYHDHKIRALGVSNYFI 704 R W + +Y + +A+GVSN+ + Sbjct: 116 WGQVGRVYDEANLDVWQAMEAIYQSGRAKAIGVSNFAV 153 >UniRef50_Q7JVH6 Cluster: LD24696p; n=2; Sophophora|Rep: LD24696p - Drosophila melanogaster (Fruit fly) Length = 311 Score = 79.8 bits (188), Expect = 2e-13 Identities = 52/155 (33%), Positives = 80/155 (51%), Gaps = 6/155 (3%) Frame = +3 Query: 252 LNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPK 431 LNNG EMP +GL T+K + AL GYR DTA +Y NE + A + + + Sbjct: 10 LNNGREMPTLGLGTWKSFES-DAYHSTRHALDVGYRHLDTAFVYENEAEVGQAISEKIAE 68 Query: 432 YKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLDFENRN 611 + R ++F+ +KL ++ A+ ERA +LSNLGL+Y+DLYL+H P K ++ Sbjct: 69 GVVTREEVFVTTKLGGIHHDP-ALVERACRLSLSNLGLEYVDLYLMHMPVGQKFHNDSNV 127 Query: 612 SSRIR------KQTWATLVDLYHDHKIRALGVSNY 698 + TW + L R++G+SN+ Sbjct: 128 HGTLELTDVDYLDTWREMEKLVDLGLTRSIGLSNF 162 >UniRef50_Q4PE96 Cluster: Putative uncharacterized protein; n=1; Ustilago maydis|Rep: Putative uncharacterized protein - Ustilago maydis (Smut fungus) Length = 293 Score = 79.8 bits (188), Expect = 2e-13 Identities = 51/160 (31%), Positives = 77/160 (48%) Frame = +3 Query: 219 DFKYILPQQFTLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVY 398 D K L T+ +G MP G+ + M ++ KAGYR DTA Y NE Sbjct: 10 DEKLTLGSSITMVDGYAMPRFGIGAWDMRGSECKQALLNAFDKAGYRHVDTARYYRNEAD 69 Query: 399 LNFAFKKLLPKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNP 578 A ++ + R ++F +K+ GGG+ T A ++L+ GLDY+DL L+H P Sbjct: 70 CGEAVREC----SVPRSELFYTTKVYLNEMGGGSKTRLAVEDSLAKAGLDYLDLVLLHAP 125 Query: 579 GIYKLDFENRNSSRIRKQTWATLVDLYHDHKIRALGVSNY 698 + R +W TL +L + K+R+LGVSN+ Sbjct: 126 D---------GGKKFRLDSWDTLTELVQEGKVRSLGVSNF 156 >UniRef50_Q8EVT8 Cluster: Oxidoreductase-aldo/keto reductase family; n=1; Mycoplasma penetrans|Rep: Oxidoreductase-aldo/keto reductase family - Mycoplasma penetrans Length = 299 Score = 79.4 bits (187), Expect = 2e-13 Identities = 45/115 (39%), Positives = 66/115 (57%) Frame = +3 Query: 237 PQQFTLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFK 416 P TLN+G ++P IGL T + H T + AL+ G R+FDTA+LYGNE + Sbjct: 34 PPLLTLNDGYQIPIIGLGTTSL-HNQTCKNAIKAALEIGIRLFDTASLYGNEKEVG---- 88 Query: 417 KLLPKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPG 581 + + + + R +IF+I+KL P A E+A L+ L DYID+ L+H+PG Sbjct: 89 ETIRESNINRNEIFVITKLYP--GAQFANPEKAIEEALNKLNTDYIDMMLLHHPG 141 >UniRef50_UPI00015B56A2 Cluster: PREDICTED: similar to GA10458-PA; n=2; Nasonia vitripennis|Rep: PREDICTED: similar to GA10458-PA - Nasonia vitripennis Length = 569 Score = 79.0 bits (186), Expect = 3e-13 Identities = 47/114 (41%), Positives = 63/114 (55%) Frame = +3 Query: 249 TLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLP 428 T N+G +MP IGL TF + V + V A++ GYR DTA Y NE + A ++ + Sbjct: 7 TFNDGYKMPMIGLGTF-LSKPGEVAEAVKYAIEVGYRHVDTAFFYENEKEIGSAIREKIN 65 Query: 429 KYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYK 590 +KR DIF+ +KL CN A +L NLG DYIDL+LVH P +K Sbjct: 66 DGTIKREDIFVTTKLW-CNSHKEDEVVPACKKSLENLGFDYIDLFLVHWPFAFK 118 Score = 65.3 bits (152), Expect = 4e-09 Identities = 43/122 (35%), Positives = 65/122 (53%), Gaps = 7/122 (5%) Frame = +3 Query: 354 YRMFDTAALYGNEVYLNFAFKKLLPKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLS 533 YR DTA LY NE Y+ A ++ + +KR D+F+ +KL + V A +L+ Sbjct: 301 YRHIDTAYLYDNEKYIGNAIREKIKDGTVKREDLFVTTKLSYYAHKESEVVP-ACKQSLN 359 Query: 534 NLGLDYIDLYLVHNPGIYKLDFENRNSS-------RIRKQTWATLVDLYHDHKIRALGVS 692 +LGLDYIDLYL+H P I + N+N+S +TW + + R++GVS Sbjct: 360 DLGLDYIDLYLIHWP-IRRYFRHNKNASGKLLLSDTDYLETWKGMEECKRQGLARSIGVS 418 Query: 693 NY 698 N+ Sbjct: 419 NF 420 >UniRef50_UPI00006CCCD7 Cluster: oxidoreductase, aldo/keto reductase family protein; n=1; Tetrahymena thermophila SB210|Rep: oxidoreductase, aldo/keto reductase family protein - Tetrahymena thermophila SB210 Length = 323 Score = 79.0 bits (186), Expect = 3e-13 Identities = 57/169 (33%), Positives = 84/169 (49%), Gaps = 8/169 (4%) Frame = +3 Query: 216 EDFKYILPQQFTLNNGVEMPAIGLDT--FKMGHFYTVLQT---VDDALKAGYRMFDTAAL 380 +D KY+ LNNG +MP +GL T + + TV + + +AL GYR FDTA Sbjct: 10 QDIKYV-----QLNNGYKMPLLGLGTQPYDIVTRVTVEEMTTLLSNALDFGYRNFDTAKQ 64 Query: 381 YGNEVYLNFAFKKLLPKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDL 560 Y NEV + AF+ + + K KR D+FI +KL P + + N+L L YIDL Sbjct: 65 YRNEVEIGQAFQNIFQQGKYKREDVFITTKLFP--FKIEKKIKEVVQNSLDQLQTSYIDL 122 Query: 561 YLVH---NPGIYKLDFENRNSSRIRKQTWATLVDLYHDHKIRALGVSNY 698 YL+ P + D + R + W L + IR++GV+N+ Sbjct: 123 YLIQWSFTPVLTNFDGSVAVNHRPIHEVWRELEECVELGMIRSIGVANF 171 >UniRef50_UPI0000498F1F Cluster: oxidoreductase, aldo/keto reductase family; n=2; Entamoeba histolytica HM-1:IMSS|Rep: oxidoreductase, aldo/keto reductase family - Entamoeba histolytica HM-1:IMSS Length = 305 Score = 79.0 bits (186), Expect = 3e-13 Identities = 52/154 (33%), Positives = 81/154 (52%), Gaps = 1/154 (0%) Frame = +3 Query: 246 FTLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLL 425 FTLNNG ++P +GL T+ M V + V+ A+K GYR D A YGNE + K + Sbjct: 5 FTLNNGYKIPKLGLGTW-MSANGEVGKAVEIAIKNGYRHIDCAKAYGNEKEVGDGIKSAI 63 Query: 426 PKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNP-GIYKLDFE 602 K +KR ++F+ +KL + V A +L L L+Y+DLY++H P K E Sbjct: 64 AKGYVKREELFVTTKLWSTDKHKEDV-RPACLESLKKLQLEYLDLYIIHIPLTADKKTGE 122 Query: 603 NRNSSRIRKQTWATLVDLYHDHKIRALGVSNYFI 704 ++TW + L + ++++GVSN+ I Sbjct: 123 FTEEIIPIEETWREMEKLVEEGLVKSIGVSNFNI 156 >UniRef50_Q2S340 Cluster: Aldehyde reductase; n=10; Bacteria|Rep: Aldehyde reductase - Salinibacter ruber (strain DSM 13855) Length = 321 Score = 79.0 bits (186), Expect = 3e-13 Identities = 56/163 (34%), Positives = 80/163 (49%), Gaps = 8/163 (4%) Frame = +3 Query: 240 QQFTLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKK 419 Q + NG EMP IGL T+K V + V AL+AGYR D A +Y NE + A Sbjct: 2 QSISFENGDEMPMIGLGTWKSPPG-EVYEAVTTALEAGYRHVDCAPIYKNETEVGAALSD 60 Query: 420 LLPKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIY--KL 593 ++R D+++ SKL + V A TLS+L LD +DLYL+H P ++ Sbjct: 61 SFDAGGIRRDDVWVTSKLWNNAHHPDDV-RPALEQTLSDLRLDALDLYLIHWPVALQPEV 119 Query: 594 DFENRNSSRIR------KQTWATLVDLYHDHKIRALGVSNYFI 704 DF + +TWA + L D +R +GVSN+ + Sbjct: 120 DFPESPDDFVSPEAVPLTETWAAMEALKKDGLVRHIGVSNFSV 162 >UniRef50_Q1VRG6 Cluster: YvgN; n=1; Psychroflexus torquis ATCC 700755|Rep: YvgN - Psychroflexus torquis ATCC 700755 Length = 280 Score = 79.0 bits (186), Expect = 3e-13 Identities = 53/152 (34%), Positives = 78/152 (51%), Gaps = 2/152 (1%) Frame = +3 Query: 252 LNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPK 431 LN+G +P +G T+K + AL GYR+ DT A+Y NE A K + Sbjct: 5 LNDGNRIPIVGFGTYKANEEEGIKSIQKSALTLGYRLIDTVAIYQNEE----AVGKAIKA 60 Query: 432 YKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNP--GIYKLDFEN 605 + R +IF+ +KL N G T A +L L L+YIDLYL+H P I D++ Sbjct: 61 RGVLREEIFVTTKLWRENL-GYKQTRIALDESLRKLDLNYIDLYLIHWPANAINYKDWQK 119 Query: 606 RNSSRIRKQTWATLVDLYHDHKIRALGVSNYF 701 N+ TW + +L + KI++LGVSN++ Sbjct: 120 TNA-----DTWRAMEELQAEGKIKSLGVSNFW 146 >UniRef50_A0JX62 Cluster: 2,5-didehydrogluconate reductase; n=9; Bacteria|Rep: 2,5-didehydrogluconate reductase - Arthrobacter sp. (strain FB24) Length = 291 Score = 79.0 bits (186), Expect = 3e-13 Identities = 57/165 (34%), Positives = 87/165 (52%), Gaps = 13/165 (7%) Frame = +3 Query: 243 QFTLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKL 422 + +LNNGV + +G +K+ V AL+AGYR FDTAA+YGNE + A L Sbjct: 6 RLSLNNGVLIDQLGFGLYKVPPA-DAAGLVTMALEAGYRHFDTAAMYGNETGVGKAIGAL 64 Query: 423 L-------------PKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLY 563 L R D+F+ +K+ ++G A T RAF ++SNLG++Y+DLY Sbjct: 65 AGFAGGGPAGGSGEAAPSLSREDLFVTTKVWNDDHGYDA-TMRAFDTSMSNLGMEYVDLY 123 Query: 564 LVHNPGIYKLDFENRNSSRIRKQTWATLVDLYHDHKIRALGVSNY 698 L+H P + F +++ + LY + +IRA+GVSN+ Sbjct: 124 LIHWPCARRGLF---------TESYRAMETLYREGRIRAIGVSNF 159 >UniRef50_A2R6Z3 Cluster: Catalytic activity: an alcohol + NADP(+) <=> an aldehyde + NADPH; n=9; Pezizomycotina|Rep: Catalytic activity: an alcohol + NADP(+) <=> an aldehyde + NADPH - Aspergillus niger Length = 345 Score = 79.0 bits (186), Expect = 3e-13 Identities = 58/166 (34%), Positives = 85/166 (51%), Gaps = 11/166 (6%) Frame = +3 Query: 234 LPQQFTLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAF 413 L + F LN G +MPA+GL T++ V V ALK GYR D AA+YGNE + Sbjct: 3 LNRTFKLNTGYDMPAVGLGTWQSKKD-EVRDAVIAALKCGYRHIDAAAVYGNEQEVGDGM 61 Query: 414 KKLLPKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYK- 590 + + R +IF+ SKL ++ V E A +L++L DY+DLYL+H P ++ Sbjct: 62 R----LSGVPREEIFLTSKLWNTHHHPENV-EEAVDKSLADLQTDYLDLYLIHWPVAFRY 116 Query: 591 ----LDFENRNSSRIR------KQTWATLVDLYHDHKIRALGVSNY 698 + N + I K TWA + L K+R++GVSN+ Sbjct: 117 STTTIQPVNEQTGLIDVVDVPIKDTWAAMEKLVEKGKVRSIGVSNF 162 >UniRef50_P47137 Cluster: Probable oxidoreductase YJR096W; n=8; Saccharomycetales|Rep: Probable oxidoreductase YJR096W - Saccharomyces cerevisiae (Baker's yeast) Length = 282 Score = 79.0 bits (186), Expect = 3e-13 Identities = 52/159 (32%), Positives = 85/159 (53%), Gaps = 3/159 (1%) Frame = +3 Query: 231 ILPQQFTLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFA 410 ++P+ + L+NG ++P+I L T+ + T + V + +K GYR FDTA LYGNE + Sbjct: 1 MVPKFYKLSNGFKIPSIALGTYDIPRSQTA-EIVYEGVKCGYRHFDTAVLYGNEKEVGDG 59 Query: 411 FKKLLPK--YKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNL-GLDYIDLYLVHNPG 581 K L + KR +IF +KL + G + A L+ + GL YIDL L+H+P Sbjct: 60 IIKWLNEDPGNHKREEIFYTTKLWN-SQNGYKRAKAAIRQCLNEVSGLQYIDLLLIHSP- 117 Query: 582 IYKLDFENRNSSRIRKQTWATLVDLYHDHKIRALGVSNY 698 S++R +TW + + + ++++GVSNY Sbjct: 118 --------LEGSKLRLETWRAMQEAVDEGLVKSIGVSNY 148 >UniRef50_UPI00006CD296 Cluster: oxidoreductase, aldo/keto reductase family protein; n=1; Tetrahymena thermophila SB210|Rep: oxidoreductase, aldo/keto reductase family protein - Tetrahymena thermophila SB210 Length = 295 Score = 78.6 bits (185), Expect = 4e-13 Identities = 50/150 (33%), Positives = 75/150 (50%), Gaps = 1/150 (0%) Frame = +3 Query: 252 LNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPK 431 L NG ++P GL T+K+ ++ + AL GYR DTA +Y NE + A +++ + Sbjct: 10 LCNGSKLPVFGLGTYKVVSKEEMVTFLRTALDLGYRHIDTAIMYENEKQIGDALQEIYKE 69 Query: 432 YKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLD-FENR 608 K KR D+F+++KL E +L NL +YIDLYL+H D FE Sbjct: 70 GKYKREDLFLVTKLFS---NKNTKVEDQVRQSLQNLQTNYIDLYLLHYASSPPTDQFELT 126 Query: 609 NSSRIRKQTWATLVDLYHDHKIRALGVSNY 698 + Q WA +L IR +G+SN+ Sbjct: 127 HKPVF--QVWAEFEELVQKGLIRNIGISNF 154 >UniRef50_A4RQH8 Cluster: Predicted protein; n=2; Ostreococcus|Rep: Predicted protein - Ostreococcus lucimarinus CCE9901 Length = 337 Score = 78.6 bits (185), Expect = 4e-13 Identities = 52/148 (35%), Positives = 75/148 (50%), Gaps = 1/148 (0%) Frame = +3 Query: 258 NGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPKYK 437 NG+ +P +GL T+K V V DAL AGY D AA Y NE + A ++ + Sbjct: 12 NGLRIPRVGLGTWK-ARPNEVRDAVRDALGAGYAHVDCAAAYANESEVGEALREAFERGD 70 Query: 438 LKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLDFENRNSS 617 KR D+F+ SKL V E A TL++LG+ Y+DLYL+H P +K + + Sbjct: 71 AKREDVFVTSKLWNDRRRPRDVRE-ALMTTLNDLGVGYLDLYLIHWPVAWKRGTVLQPDA 129 Query: 618 RIR-KQTWATLVDLYHDHKIRALGVSNY 698 + W+ L D +R +GVSN+ Sbjct: 130 EASIAECWSELERCVADGLVRHIGVSNF 157 >UniRef50_Q968S3 Cluster: Aldoketoreductase-like protein; n=1; Orconectes limosus|Rep: Aldoketoreductase-like protein - Orconectes limosus (Spinycheek crayfish) Length = 336 Score = 78.6 bits (185), Expect = 4e-13 Identities = 47/130 (36%), Positives = 69/130 (53%), Gaps = 6/130 (4%) Frame = +3 Query: 252 LNNGVEMPAIGLDTFKMGHF-----YTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFK 416 LN+G +P +GL T +G V ++ AL+ GYR FD+AA YGNE + + Sbjct: 16 LNSGSHIPVMGLGTGSLGRNGKMSEEAVTAVLETALECGYRHFDSAAYYGNEAIIGQVLR 75 Query: 417 KLLPKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNP-GIYKL 593 + + + K+KR ++FI +K LP R +L NL L Y+DLYLVH P GI Sbjct: 76 RWISEGKVKREELFITTK-LPTRGNREKDVARFLQKSLDNLRLPYVDLYLVHYPCGILDT 134 Query: 594 DFENRNSSRI 623 D E ++ + Sbjct: 135 DRERLSADEV 144 >UniRef50_Q9C1X5 Cluster: Xylose and arabinose reductase; n=1; Schizosaccharomyces pombe|Rep: Xylose and arabinose reductase - Schizosaccharomyces pombe (Fission yeast) Length = 283 Score = 78.6 bits (185), Expect = 4e-13 Identities = 53/150 (35%), Positives = 74/150 (49%) Frame = +3 Query: 249 TLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLP 428 TL NG+ +P IG F + + V AL +GYR DTAA+YGNE A Sbjct: 12 TLTNGMVIPRIGFGAFML-KYNECYGLVTQALDSGYRHIDTAAVYGNEDICGKAIVDWCE 70 Query: 429 KYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLDFENR 608 K +KR DIF+ SKL C+ T A ++L +LG YIDL+L+ +P Sbjct: 71 KNNVKRTDIFLTSKLANCS--DYYSTRAAIRSSLHHLG-TYIDLFLIQSPA--------- 118 Query: 609 NSSRIRKQTWATLVDLYHDHKIRALGVSNY 698 + R +W + + IR++GVSNY Sbjct: 119 GGKKSRIASWKAMEEFVDSGDIRSVGVSNY 148 >UniRef50_Q7VHE1 Cluster: Putative uncharacterized protein; n=1; Helicobacter hepaticus|Rep: Putative uncharacterized protein - Helicobacter hepaticus Length = 270 Score = 78.2 bits (184), Expect = 5e-13 Identities = 43/113 (38%), Positives = 66/113 (58%) Frame = +3 Query: 240 QQFTLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKK 419 Q TLNNGV+MP +GL T+ + + + +A++ GYR+FD+A +Y NE L A Sbjct: 2 QTLTLNNGVKMPILGLGTYSLTG-KAGQKAMSEAIEVGYRLFDSAQMYNNEAELGAAINA 60 Query: 420 LLPKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNP 578 + K +KR + FI +KLL + + +++ +L LGLDYID L+H P Sbjct: 61 AV-KGGIKREEFFIQTKLLESS--SEDLAKKSIEKSLKTLGLDYIDSLLIHMP 110 >UniRef50_Q4Q5N9 Cluster: Prostaglandin f synthase, putative; n=7; cellular organisms|Rep: Prostaglandin f synthase, putative - Leishmania major Length = 279 Score = 77.8 bits (183), Expect = 7e-13 Identities = 53/150 (35%), Positives = 80/150 (53%) Frame = +3 Query: 249 TLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLP 428 TL+NGV++P +G+ T++ V+ + A+ AGYR DTA Y NE + + Sbjct: 9 TLSNGVQVPQLGIGTWEAKDGNEVVN-IKWAVNAGYRHVDTAHYYKNEKGVGQGISEC-- 65 Query: 429 KYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLDFENR 608 + R DIF+ +KL ++G + AF + LG++Y+DLYL+H PG Sbjct: 66 --GVPRSDIFVTTKLWNYDHGYESALA-AFEQSRQALGVEYVDLYLIHWPG--------P 114 Query: 609 NSSRIRKQTWATLVDLYHDHKIRALGVSNY 698 N S I +TW LY K+RA+GVSN+ Sbjct: 115 NRSYI--ETWRAFEKLYEMKKVRAIGVSNF 142 >UniRef50_Q17G72 Cluster: Aldo-keto reductase; n=9; Endopterygota|Rep: Aldo-keto reductase - Aedes aegypti (Yellowfever mosquito) Length = 316 Score = 77.8 bits (183), Expect = 7e-13 Identities = 53/160 (33%), Positives = 88/160 (55%), Gaps = 10/160 (6%) Frame = +3 Query: 249 TLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLP 428 T NG MPA+G T++ V + +++AL+AGYR DTA +Y NE + K+ + Sbjct: 8 TFENGTTMPALGFGTWRASD-EEVEKALNEALEAGYRHIDTAPVYLNEKTIGKVLKEWMD 66 Query: 429 KYKLKRGDIFIISKLLPCNYGGGAVT-ERAFHNTLSNLGLDYIDLYLVHNP-GIYKLD-- 596 K+ R ++FI++KL P +G A T E+ N+L +L L+Y+DLY VH P + ++D Sbjct: 67 AGKVTRDELFIVTKLPP--HGTRASTVEKFLKNSLDDLQLEYVDLYHVHVPFTVPEVDGP 124 Query: 597 FENRNSSRIRKQT------WATLVDLYHDHKIRALGVSNY 698 F + + + T W + ++Y R +G+SN+ Sbjct: 125 FLVEDGLIVLETTTDHVALWKAMEEVYEAGLARNIGLSNF 164 >UniRef50_UPI0000519CC2 Cluster: PREDICTED: similar to CG2767-PA; n=1; Apis mellifera|Rep: PREDICTED: similar to CG2767-PA - Apis mellifera Length = 321 Score = 77.4 bits (182), Expect = 9e-13 Identities = 56/162 (34%), Positives = 79/162 (48%), Gaps = 11/162 (6%) Frame = +3 Query: 252 LNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPK 431 L NG MP IG T++ + ++ AL+AGYR DTA Y NE + K Sbjct: 8 LPNGELMPIIGFGTWQAQE-KELEDALNIALEAGYRHIDTATSYENEKVIGDVLKNWFDS 66 Query: 432 YKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNP-GIYKL----- 593 KLKR DIFI++K LP E+ +L NL L+Y+DLYL+H P G K+ Sbjct: 67 KKLKRSDIFIVTK-LPAVGNRAEDVEKWIKTSLQNLRLEYLDLYLIHVPIGFEKVGDILH 125 Query: 594 DFENRNSSRIRKQT-----WATLVDLYHDHKIRALGVSNYFI 704 F+ R+ T WA + + +A+G+SN+ I Sbjct: 126 PFDENGHIRLDNSTNHVEIWAEMEKQVKCGRTKAIGLSNFNI 167 >UniRef50_Q8Y463 Cluster: Lmo2592 protein; n=40; Bacteria|Rep: Lmo2592 protein - Listeria monocytogenes Length = 283 Score = 77.4 bits (182), Expect = 9e-13 Identities = 53/149 (35%), Positives = 76/149 (51%) Frame = +3 Query: 252 LNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPK 431 LNNGVE+P +G T+++ V DA+KAGYR DTA Y NE A + + Sbjct: 6 LNNGVEVPILGFGTYQITDAAEAEHAVKDAIKAGYRHIDTAQSYMNEE----AVGRGIAA 61 Query: 432 YKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLDFENRN 611 + R ++FI +K+ N V +F +L LGLDY+DL L+H P F + Sbjct: 62 SGVDRKELFITTKIWVENVSYKGVMS-SFDRSLKRLGLDYVDLLLIHQP------FNDVY 114 Query: 612 SSRIRKQTWATLVDLYHDHKIRALGVSNY 698 + W + +L KIRA+GVSN+ Sbjct: 115 GA------WIAMEELQASGKIRAIGVSNF 137 >UniRef50_Q4PDR0 Cluster: Putative uncharacterized protein; n=1; Ustilago maydis|Rep: Putative uncharacterized protein - Ustilago maydis (Smut fungus) Length = 339 Score = 77.0 bits (181), Expect = 1e-12 Identities = 58/172 (33%), Positives = 90/172 (52%), Gaps = 19/172 (11%) Frame = +3 Query: 246 FTLNNGVEMPAIGLDTFK----MGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAF 413 FTLN G ++P++G+ ++ G ++ + A+K GYR DTA Y NE + A Sbjct: 8 FTLNTGAKLPSVGMGCWQGQPGPGRDNELVDALVRAIKVGYRHLDTATGYRNEAEVGQAV 67 Query: 414 KKLLPKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNP-GIYK 590 ++ + R +IF+ +KL P GG + N+L+ LG+DYIDL+L+H P G K Sbjct: 68 RQS----GVARSEIFVTTKLRP---GGVHDVVQELENSLNELGIDYIDLWLLHWPQGFTK 120 Query: 591 LD--FENRNSSRIRKQ---------TWATLVDLY---HDHKIRALGVSNYFI 704 D F S + Q TWA + D++ H K++A+GVSN+ I Sbjct: 121 DDGGFGTGESFGLEHQKHLGPTFNETWAKMEDVFLNSHKGKVKAIGVSNFSI 172 >UniRef50_Q88TV9 Cluster: Oxidoreductase; n=4; Lactobacillus|Rep: Oxidoreductase - Lactobacillus plantarum Length = 288 Score = 76.6 bits (180), Expect = 2e-12 Identities = 47/110 (42%), Positives = 62/110 (56%) Frame = +3 Query: 249 TLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLP 428 TLN+G +PAIG TF++ + Q V +AL GYR DTA Y NE + A K Sbjct: 8 TLNDGRAIPAIGFGTFQIPDDGSTYQAVKEALVIGYRHIDTAVAYFNEDEVGQAIK---- 63 Query: 429 KYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNP 578 + R I++ SKL +YG A + RA +L+ L LDYIDLYL+H P Sbjct: 64 DSGIPRDQIWVTSKLWLQDYGFDAAS-RAIDRSLTKLRLDYIDLYLIHQP 112 >UniRef50_A6VNW9 Cluster: Aldo/keto reductase precursor; n=1; Actinobacillus succinogenes 130Z|Rep: Aldo/keto reductase precursor - Actinobacillus succinogenes 130Z Length = 315 Score = 76.2 bits (179), Expect = 2e-12 Identities = 56/151 (37%), Positives = 80/151 (52%), Gaps = 2/151 (1%) Frame = +3 Query: 252 LNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPK 431 LNNG+EMP IG+ + + T ++V +ALKAGYR+ DTA +Y NE A + + Sbjct: 47 LNNGIEMPIIGIGVWTLTPEQTE-KSVGEALKAGYRLIDTARMYRNEQ----AVGRAVRD 101 Query: 432 YKLKRGDIFIISKLLPCNYGGG--AVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLDFEN 605 + R +IFI +K+ YG G A E A + L L DYIDL L+H P + Sbjct: 102 SGIPREEIFITTKI----YGSGDYANAEAAINERLRLLDTDYIDLLLLHYP--------D 149 Query: 606 RNSSRIRKQTWATLVDLYHDHKIRALGVSNY 698 +N ++ W + KIRA+G+SNY Sbjct: 150 QNDTK----AWKVMEQFVKAGKIRAIGLSNY 176 >UniRef50_Q10494 Cluster: Probable oxidoreductase C26F1.07; n=2; Schizosaccharomyces pombe|Rep: Probable oxidoreductase C26F1.07 - Schizosaccharomyces pombe (Fission yeast) Length = 321 Score = 76.2 bits (179), Expect = 2e-12 Identities = 53/160 (33%), Positives = 83/160 (51%), Gaps = 9/160 (5%) Frame = +3 Query: 246 FTLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLL 425 FTL +G ++P +GL T++ T V AL+ GYR D AA+YGNE + K+ Sbjct: 16 FTLADGSKIPGLGLGTWRSEPNQTK-NAVKTALQYGYRHIDAAAIYGNEDEVGDGIKES- 73 Query: 426 PKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLDFE- 602 + R DI++ SKL CN +A TL +L LDY+D YL+H P +K + Sbjct: 74 ---GVPRKDIWVTSKLW-CNAHAPEAVPKALEKTLKDLKLDYLDEYLIHWPVSFKTGEDK 129 Query: 603 ---NRNSSRIR-----KQTWATLVDLYHDHKIRALGVSNY 698 +++ + I ++TW + L K+R +G+SN+ Sbjct: 130 FPKDKDGNLIYEKNPIEETWKAMEKLLETGKVRHIGLSNF 169 >UniRef50_A7ALH6 Cluster: Putative uncharacterized protein; n=1; Parabacteroides merdae ATCC 43184|Rep: Putative uncharacterized protein - Parabacteroides merdae ATCC 43184 Length = 301 Score = 75.8 bits (178), Expect = 3e-12 Identities = 51/149 (34%), Positives = 79/149 (53%) Frame = +3 Query: 252 LNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPK 431 LNNG+EMP +G+ TF + + V A+K G+R+ DTA YGNE + + + Sbjct: 34 LNNGMEMPQLGVGTFLVKD--NAAERVCHAIKVGFRLIDTAQGYGNEKEVGEG----ICR 87 Query: 432 YKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLDFENRN 611 + R ++FI +K+ GG V + + +L++LG DYIDL L+H P + Sbjct: 88 SGIDRRELFITTKVNTMEMRGGTVRQ-SLDKSLADLGTDYIDLVLIHWPVKGHI------ 140 Query: 612 SSRIRKQTWATLVDLYHDHKIRALGVSNY 698 K+TW L + KIR++GVSN+ Sbjct: 141 -----KETWQILEEYVDKGKIRSIGVSNF 164 >UniRef50_A2QBD7 Cluster: Catalytic activity: an alcohol + NADP(+) <=> an aldehyde + NADPH; n=4; Trichocomaceae|Rep: Catalytic activity: an alcohol + NADP(+) <=> an aldehyde + NADPH - Aspergillus niger Length = 323 Score = 75.8 bits (178), Expect = 3e-12 Identities = 59/168 (35%), Positives = 85/168 (50%), Gaps = 11/168 (6%) Frame = +3 Query: 234 LPQQFTLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAF 413 LP FT+N G ++PA+G T++ V V+ AL+ GYR D AA+Y NE + Sbjct: 3 LPSHFTINTGAKIPAVGFGTWQAKPL-EVENAVEVALREGYRHIDCAAIYRNETEVGNGI 61 Query: 414 KKLLPKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYK- 590 +K + R +IFI KL + V E A TL +LG+ Y+DLYL+H P +K Sbjct: 62 RKS----GVPREEIFITGKLWNTKHAPEDV-EPALDKTLQDLGVAYLDLYLMHWPCAFKG 116 Query: 591 ------LD----FENRNSSRIRKQTWATLVDLYHDHKIRALGVSNYFI 704 L+ F+ N I T+ + L K+RA+GVSN+ I Sbjct: 117 GDKWFPLNDDGVFDLANIDYI--TTYRAMEKLLATGKVRAIGVSNFNI 162 >UniRef50_UPI00015B56A3 Cluster: PREDICTED: similar to aldo-keto reductase; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to aldo-keto reductase - Nasonia vitripennis Length = 321 Score = 75.4 bits (177), Expect = 4e-12 Identities = 51/162 (31%), Positives = 88/162 (54%), Gaps = 10/162 (6%) Frame = +3 Query: 243 QFTLNNGVEMPAIGLDTFKMGHFYTVLQT-VDDALKAGYRMFDTAALYGNEVYLNFAFKK 419 + TL++G ++P +GL T++ G+ ++ V A+ AGYR FD A+ YGNE + A ++ Sbjct: 7 EITLSDGNKVPVLGLGTWQGGNDPDEVENAVKLAIDAGYRHFDCASFYGNEAEIGKAIQE 66 Query: 420 LLPKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLDF 599 + + +KR D+F+++K+ V A +L LGL YIDLYLVH P Y + + Sbjct: 67 KIDQGVVKREDLFVVTKVWNDERKQELVV-AACKRSLKKLGLGYIDLYLVHWPFSYPILY 125 Query: 600 E-----NRNSSRIRK----QTWATLVDLYHDHKIRALGVSNY 698 + N+ + + +TW + + R++GVSN+ Sbjct: 126 QYIVLPTYNAVTLDEVDYIETWRGMEECIKLGLTRSIGVSNF 167 >UniRef50_Q1IN88 Cluster: Aldehyde reductase; n=5; Bacteria|Rep: Aldehyde reductase - Acidobacteria bacterium (strain Ellin345) Length = 313 Score = 75.4 bits (177), Expect = 4e-12 Identities = 55/159 (34%), Positives = 83/159 (52%), Gaps = 11/159 (6%) Frame = +3 Query: 252 LNNGV-EMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLP 428 L++G +PA+G T T+ T DAL AG+R FD A Y NE + A + Sbjct: 13 LHHGAGHIPALGFGTLIADPALTITAT-RDALAAGFRHFDCAERYRNEREVGEALRAGRA 71 Query: 429 KYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIY----KLD 596 + R +IF+ +KL N+ V E AF +L LGLDY+DLYL+H P + + D Sbjct: 72 AGNIAREEIFVTTKLWNTNHRPERV-EPAFEASLDRLGLDYLDLYLIHTPFAFQPGDEQD 130 Query: 597 FENRNSSRI------RKQTWATLVDLYHDHKIRALGVSN 695 ++N S I ++TW+ L +L + RA+G+S+ Sbjct: 131 PRDQNGSVIYDEGVTLRETWSALENLVDRGRCRAIGLSD 169 >UniRef50_Q9Y020 Cluster: 3-dehydroecdysone 3beta-reductase precursor; n=1; Spodoptera littoralis|Rep: 3-dehydroecdysone 3beta-reductase precursor - Spodoptera littoralis (Egyptian cotton leafworm) Length = 345 Score = 75.4 bits (177), Expect = 4e-12 Identities = 50/155 (32%), Positives = 79/155 (50%), Gaps = 8/155 (5%) Frame = +3 Query: 258 NGVEMPAIGLDT---FKMGHFYT-----VLQTVDDALKAGYRMFDTAALYGNEVYLNFAF 413 N EMPAI L T F G T + V A+ GYR FDTAA+Y E + A Sbjct: 29 NDREMPAIALGTYLGFDKGGAVTSKDKQLRNVVMQAIDLGYRHFDTAAIYNTEAEVGEAI 88 Query: 414 KKLLPKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKL 593 + + + +KR D+F+ +KL ++ V A TL+ GLDY+DL+L+H P Sbjct: 89 RMKIDEGVIKREDVFLTTKLWNTHHKREQVAV-AMKETLNKTGLDYVDLFLMHWPIALNE 147 Query: 594 DFENRNSSRIRKQTWATLVDLYHDHKIRALGVSNY 698 D+ + N+ + +TW ++ +++G+SN+ Sbjct: 148 DYSHSNTDYL--ETWRATEEMVKLGYTKSIGLSNF 180 >UniRef50_A2QVE5 Cluster: Similarity: shows similarity to several dehydrogenases of different specificities; n=4; Pezizomycotina|Rep: Similarity: shows similarity to several dehydrogenases of different specificities - Aspergillus niger Length = 381 Score = 75.4 bits (177), Expect = 4e-12 Identities = 48/116 (41%), Positives = 65/116 (56%), Gaps = 1/116 (0%) Frame = +3 Query: 234 LPQQFTLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAF 413 L ++ TLN+G ++P +G T++ V V +ALKAGYR D A +Y N+ + Sbjct: 3 LGKKVTLNSGAQIPQLGFGTWQSAPGQ-VGDAVYEALKAGYRHLDLATIYQNQREVAEGI 61 Query: 414 KKLLPKYK-LKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNP 578 K+ LKR DIFI SKL + AV E+A L+ L LDY+DLYLVH P Sbjct: 62 KRAYKDVPGLKREDIFITSKLWNSQHDP-AVVEKALDECLAELELDYLDLYLVHWP 116 >UniRef50_P14550 Cluster: Alcohol dehydrogenase [NADP+]; n=44; Bilateria|Rep: Alcohol dehydrogenase [NADP+] - Homo sapiens (Human) Length = 325 Score = 75.4 bits (177), Expect = 4e-12 Identities = 58/159 (36%), Positives = 80/159 (50%), Gaps = 10/159 (6%) Frame = +3 Query: 252 LNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKK-LLP 428 L+ G +MP IGL T+K V V AL GYR D AA+YGNE + A K+ + P Sbjct: 8 LHTGQKMPLIGLGTWK-SEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALKEDVGP 66 Query: 429 KYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVH---------NPG 581 + R ++F+ SKL + V E A TL++L L+Y+DLYL+H NP Sbjct: 67 GKAVPREELFVTSKLWNTKHHPEDV-EPALRKTLADLQLEYLDLYLMHWPYAFERGDNPF 125 Query: 582 IYKLDFENRNSSRIRKQTWATLVDLYHDHKIRALGVSNY 698 D S K+TW L L ++ALG+SN+ Sbjct: 126 PKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNF 164 >UniRef50_Q96UH3 Cluster: Aldehyde reductase; n=13; Pezizomycotina|Rep: Aldehyde reductase - Coccidioides posadasii Length = 314 Score = 74.9 bits (176), Expect = 5e-12 Identities = 56/160 (35%), Positives = 82/160 (51%), Gaps = 9/160 (5%) Frame = +3 Query: 246 FTLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLL 425 F LN G ++PAIG T++ + V AL AGYR DTAA+YG E A + L Sbjct: 8 FRLNTGEDIPAIGFGTWQDENAQE--DAVLTALSAGYRHIDTAAVYGTEK----AIGRAL 61 Query: 426 PKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKL--DF 599 + +L R ++FI SKL + V E+A +L NL +DY+DLYL+H P + D Sbjct: 62 ARSRLSRDELFITSKLWNNKHRPEDV-EQAIDQSLKNLEIDYLDLYLMHWPAAFAPGDDM 120 Query: 600 ENRNSSRIRK-------QTWATLVDLYHDHKIRALGVSNY 698 ++S K T+ + L K +A+G+SN+ Sbjct: 121 FPKDSQGNSKTVDIDYVDTYKAMEKLVKSGKTKAIGISNF 160 >UniRef50_Q5FKI1 Cluster: Reductase-dehydrogenase; n=1; Lactobacillus acidophilus|Rep: Reductase-dehydrogenase - Lactobacillus acidophilus Length = 271 Score = 74.5 bits (175), Expect = 7e-12 Identities = 50/150 (33%), Positives = 80/150 (53%), Gaps = 1/150 (0%) Frame = +3 Query: 252 LNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPK 431 LNNG ++P I L T+ + + V + V A+ GYR FDTA YGNE + K + Sbjct: 9 LNNGEKIPQIQLGTWLINND-EVNKVVRQAVNIGYRGFDTAKDYGNESGVG----KGIWN 63 Query: 432 YKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIY-KLDFENR 608 ++R DIF+ +KL P T++A L GL+YIDL L+H+P + +++ N Sbjct: 64 SDIERSDIFLTTKL-PTAVKDYEGTKKAIDAALDKFGLEYIDLLLIHSPQPWIEVNRTND 122 Query: 609 NSSRIRKQTWATLVDLYHDHKIRALGVSNY 698 + + W + + K+R++GVSN+ Sbjct: 123 RHFKGNLENWRAMEEAVKAGKVRSIGVSNF 152 >UniRef50_Q11BF8 Cluster: Aldo/keto reductase; n=12; Bacteria|Rep: Aldo/keto reductase - Mesorhizobium sp. (strain BNC1) Length = 308 Score = 74.5 bits (175), Expect = 7e-12 Identities = 55/147 (37%), Positives = 75/147 (51%) Frame = +3 Query: 258 NGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPKYK 437 +GVEMP IGL F+ T V++AL+ GYR DTAA YGNE + ++ Sbjct: 25 SGVEMPMIGLGVFQTPPDETTA-AVEEALRLGYRHIDTAAAYGNEREVGEGIRRA----G 79 Query: 438 LKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLDFENRNSS 617 + R ++FI +K+ +YG T AF + LG+D IDL L+H P D R Sbjct: 80 IARDEVFIETKIWISDYGYDE-TLHAFDKSAGKLGVDQIDLLLLHQPLPSAFD---RTLG 135 Query: 618 RIRKQTWATLVDLYHDHKIRALGVSNY 698 R L L D K+RA+GVSN+ Sbjct: 136 AYR-----ALEKLLADGKVRAIGVSNF 157 >UniRef50_Q03X85 Cluster: Aldo/keto reductase of diketogulonate reductase family; n=1; Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293|Rep: Aldo/keto reductase of diketogulonate reductase family - Leuconostoc mesenteroides subsp. mesenteroides (strain ATCC 8293 /NCDO 523) Length = 288 Score = 74.5 bits (175), Expect = 7e-12 Identities = 48/153 (31%), Positives = 76/153 (49%), Gaps = 2/153 (1%) Frame = +3 Query: 249 TLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLP 428 TLNNG +MP +G F++ T Q V DA+ AGYR DTA +YGNE + + Sbjct: 5 TLNNGAQMPQLGFGVFQIPAEETK-QAVVDAINAGYRSIDTARVYGNEAETGQGVNEAIA 63 Query: 429 KYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNP--GIYKLDFE 602 + R ++F+ +KL + A + A ++L LG DY DL L+H P +Y Sbjct: 64 NAVVAREELFLTTKLWLSEFSYEA-AKGAIDDSLKKLGTDYADLILLHQPYGDVY----- 117 Query: 603 NRNSSRIRKQTWATLVDLYHDHKIRALGVSNYF 701 + L + D K++++G+SN++ Sbjct: 118 ---------GAYKALAEAQADGKVKSIGISNFY 141 >UniRef50_A7SIT3 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 323 Score = 74.5 bits (175), Expect = 7e-12 Identities = 53/160 (33%), Positives = 79/160 (49%), Gaps = 9/160 (5%) Frame = +3 Query: 252 LNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPK 431 LN G +PA+ L T++ V V A++ GYR D A +YGNE + A ++L + Sbjct: 10 LNTGASIPAMALGTWQSSK-EEVGNAVRLAIELGYRHIDCAEIYGNEGEIGEALSEVLTE 68 Query: 432 YKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLDFENRN 611 K+KR ++F+ SKL C+ A TL NL LDY+DLYL+H P +K + Sbjct: 69 GKVKREELFVTSKLW-CDSHHPDDVLPACQATLKNLQLDYLDLYLIHIPVAFKKGVRLPH 127 Query: 612 S---------SRIRKQTWATLVDLYHDHKIRALGVSNYFI 704 S + TW + L +A+GVSN+ + Sbjct: 128 SIAEGIIGYTPEGVQNTWQAMEGLVAKGLCKAIGVSNFSV 167 >UniRef50_Q6C2L0 Cluster: Yarrowia lipolytica chromosome F of strain CLIB122 of Yarrowia lipolytica; n=3; Yarrowia lipolytica|Rep: Yarrowia lipolytica chromosome F of strain CLIB122 of Yarrowia lipolytica - Yarrowia lipolytica (Candida lipolytica) Length = 324 Score = 74.1 bits (174), Expect = 9e-12 Identities = 44/115 (38%), Positives = 68/115 (59%) Frame = +3 Query: 234 LPQQFTLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAF 413 + F LN+G +PA+GL T G+ V + V A+K GYR DTA +YG+EV + Sbjct: 3 ITDSFKLNDGHSIPALGLGTASDGN---VEEVVYAAIKNGYRHIDTAFIYGSEVDVGKGI 59 Query: 414 KKLLPKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNP 578 K+ + + +KR ++F+ +K+ P Y V+E + +L +L LDY+DL LVH P Sbjct: 60 KRAIDEELVKRENLFVTTKVWPTFY--NRVSE-SLDISLKDLSLDYVDLLLVHWP 111 >UniRef50_UPI00015B4B22 Cluster: PREDICTED: similar to GA15457-PA; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to GA15457-PA - Nasonia vitripennis Length = 388 Score = 73.7 bits (173), Expect = 1e-11 Identities = 53/164 (32%), Positives = 81/164 (49%), Gaps = 11/164 (6%) Frame = +3 Query: 240 QQFTLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKK 419 ++ L++G E+PA+GL T + + + AL+ GYR DTA Y NE + KK Sbjct: 24 EKLKLSSGHEIPAVGLGTSTI-KLDEMDNAISSALENGYRHIDTAFSYDNEAAIGKILKK 82 Query: 420 LLPKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLDF 599 K KR DIFI SKL P E +L +LGLDY+D+YL+H P K + Sbjct: 83 WFDKGG-KREDIFITSKL-PSQGNRPQSVETYLKRSLKDLGLDYVDMYLIHTPFAVK-EG 139 Query: 600 ENRNSSRIR-----------KQTWATLVDLYHDHKIRALGVSNY 698 EN +S + + K W + + + +++G+SN+ Sbjct: 140 ENLSSKQDKDGNDLFDDVDHKALWKAMERQVKEGRAKSIGLSNF 183 >UniRef50_Q8EUH6 Cluster: Oxidoreductase; n=1; Mycoplasma penetrans|Rep: Oxidoreductase - Mycoplasma penetrans Length = 285 Score = 73.7 bits (173), Expect = 1e-11 Identities = 56/152 (36%), Positives = 79/152 (51%), Gaps = 3/152 (1%) Frame = +3 Query: 252 LNNGVEMPAIGLDTFKM---GHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKL 422 L NG+ MP IGL +K T+++ +DD GYRM DTA +Y NE ++ A K+ Sbjct: 6 LANGLHMPIIGLGVYKAEGENCENTIIKAIDDY---GYRMIDTAQVYFNEEFVGNAIKQT 62 Query: 423 LPKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLDFE 602 K+KR DIFI +K+ NYG T + +L L +YIDL L+H P F Sbjct: 63 ----KIKREDIFITTKVWISNYGYNN-TMYSISKSLKKLQTNYIDLVLLHQP------FG 111 Query: 603 NRNSSRIRKQTWATLVDLYHDHKIRALGVSNY 698 + S+ W L LY ++A+GVSN+ Sbjct: 112 DYYSA------WKALEVLYKKGIVKAIGVSNF 137 >UniRef50_Q17DN0 Cluster: Aldo-keto reductase; n=5; Culicidae|Rep: Aldo-keto reductase - Aedes aegypti (Yellowfever mosquito) Length = 324 Score = 73.7 bits (173), Expect = 1e-11 Identities = 54/162 (33%), Positives = 80/162 (49%), Gaps = 13/162 (8%) Frame = +3 Query: 252 LNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPK 431 LNNG+EMPAIGL T M + V A+ G+R DTA Y NE + A + + + Sbjct: 11 LNNGLEMPAIGLGT-SMSKGDECCKAVMTAIDEGFRHIDTAYNYRNEDVVGRAIRAKIEE 69 Query: 432 YKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKL---DFE 602 + R ++F+ +KL + V AF +L +LGLDY+DL+L+H P Y+ D E Sbjct: 70 GVVTREELFVTTKLWNTFHHPDHVP-MAFGKSLEHLGLDYVDLFLIHMPFGYEFNGWDPE 128 Query: 603 NRN----------SSRIRKQTWATLVDLYHDHKIRALGVSNY 698 R S TW + L ++ ++GVSN+ Sbjct: 129 KRTPLDDNGNVLCSDDDYVDTWKAMEKLLESGRVHSIGVSNF 170 >UniRef50_Q929C8 Cluster: Lin2349 protein; n=12; Listeria|Rep: Lin2349 protein - Listeria innocua Length = 294 Score = 73.3 bits (172), Expect = 2e-11 Identities = 50/155 (32%), Positives = 79/155 (50%) Frame = +3 Query: 234 LPQQFTLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAF 413 L + L +P IGL F++ + V+ A++ GYR+FDTAA+Y NE + A Sbjct: 5 LQDRMILPGNETIPYIGLGVFQVTEQEFIAGAVEKAIEVGYRLFDTAAVYNNEAIVGQA- 63 Query: 414 KKLLPKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKL 593 + + R ++FI SK+ + G T AF TL NL LDY+DLYL+H P K Sbjct: 64 ---ILDSAVPREELFISSKVWNGDLGYDE-TLFAFERTLRNLKLDYLDLYLIHWPVAGKY 119 Query: 594 DFENRNSSRIRKQTWATLVDLYHDHKIRALGVSNY 698 + +W + L+ + I+++GV+N+ Sbjct: 120 -----------RDSWRAMERLHDEKLIKSIGVANF 143 >UniRef50_Q3CZS2 Cluster: Oxidoreductase, aldo/keto reductase family; n=2; Streptococcus agalactiae|Rep: Oxidoreductase, aldo/keto reductase family - Streptococcus agalactiae H36B Length = 245 Score = 73.3 bits (172), Expect = 2e-11 Identities = 45/115 (39%), Positives = 63/115 (54%) Frame = +3 Query: 234 LPQQFTLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAF 413 L Q F LNNGV++P++G F++ Q+V DAL+ GYR+ DTA+ Y NE + A Sbjct: 3 LNQFFILNNGVKIPSLGFGVFQIDDPLECEQSVLDALQVGYRLIDTASGYLNEEAVGRAI 62 Query: 414 KKLLPKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNP 578 K K + R +IF+++KL A L L LDYI+LYL+H P Sbjct: 63 K----KSGIPRKEIFVVTKLW-IQDASEEKAGPAIDRALKRLQLDYINLYLIHQP 112 >UniRef50_Q03U37 Cluster: Aldo/keto reductase of diketogulonate reductase family; n=5; Lactobacillus|Rep: Aldo/keto reductase of diketogulonate reductase family - Lactobacillus brevis (strain ATCC 367 / JCM 1170) Length = 282 Score = 73.3 bits (172), Expect = 2e-11 Identities = 53/151 (35%), Positives = 77/151 (50%) Frame = +3 Query: 252 LNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPK 431 L +G +MP +G T+ + T+ + A AGYRMFDTA LY NE L A ++L Sbjct: 12 LADGRQMPVMGFGTYLLNDQPTMNTAIQTAWDAGYRMFDTAMLYRNEDILGPAIQQL--- 68 Query: 432 YKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLDFENRN 611 L R +F+ SK+ G T +A +L L DY+DL L+H P + + F+ Sbjct: 69 -GLPREGLFLTSKVAEIVQGYDQ-TMKAVEGSLKRLQTDYLDLLLIHWP-VREHFFD--- 122 Query: 612 SSRIRKQTWATLVDLYHDHKIRALGVSNYFI 704 TW L L D +++++GVSNY I Sbjct: 123 -------TWRALEQLKADGQVKSIGVSNYTI 146 >UniRef50_Q927P9 Cluster: Lin2739 protein; n=12; Bacteria|Rep: Lin2739 protein - Listeria innocua Length = 283 Score = 72.9 bits (171), Expect = 2e-11 Identities = 51/149 (34%), Positives = 75/149 (50%) Frame = +3 Query: 252 LNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPK 431 LNNG+E+P +G T+++ Q V +A+ AGYR DTA Y NE A + + Sbjct: 6 LNNGIEVPILGFGTYQITDAGEAEQAVKEAIAAGYRHIDTAQSYMNEE----AVGRGIAA 61 Query: 432 YKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLDFENRN 611 + R ++FI +K+ N V +F +L LGLDYIDL L+H P Y + Sbjct: 62 SGVDRKELFITTKIWVENVSYKGVMS-SFDRSLKRLGLDYIDLLLIHQP--YNDVY---- 114 Query: 612 SSRIRKQTWATLVDLYHDHKIRALGVSNY 698 W + +L KI+A+GVSN+ Sbjct: 115 ------GAWMAMEELQAQGKIKAIGVSNF 137 >UniRef50_Q043M4 Cluster: Aldo/keto reductase of diketogulonate reductase family; n=2; Lactobacillus|Rep: Aldo/keto reductase of diketogulonate reductase family - Lactobacillus gasseri (strain ATCC 33323 / DSM 20243) Length = 273 Score = 72.9 bits (171), Expect = 2e-11 Identities = 52/153 (33%), Positives = 74/153 (48%) Frame = +3 Query: 240 QQFTLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKK 419 +Q TLNN V++P G T+++ T Q V A + GYR+ DTA Y NE + A K Sbjct: 2 KQLTLNNDVKIPIFGFGTYEISPDQTK-QAVLSAFEEGYRLIDTAQYYQNEQQVGEAVK- 59 Query: 420 LLPKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLDF 599 L R ++FI +K + Y T+ +L +GLDY DL L+H P + +D Sbjct: 60 ---ASGLNRDEVFITTKTMTDGYED---TKIGLDESLRRIGLDYFDLVLIHWPMGHDID- 112 Query: 600 ENRNSSRIRKQTWATLVDLYHDHKIRALGVSNY 698 TW L Y K RA+G+SN+ Sbjct: 113 -----------TWHALEAAYKAGKTRAIGISNF 134 >UniRef50_P27800 Cluster: Aldehyde reductase 1; n=18; root|Rep: Aldehyde reductase 1 - Sporobolomyces salmonicolor Length = 323 Score = 72.9 bits (171), Expect = 2e-11 Identities = 54/164 (32%), Positives = 81/164 (49%), Gaps = 14/164 (8%) Frame = +3 Query: 249 TLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLP 428 TLN G + +G T++ V Q V A++ GYR D A +Y N+ + A K+ Sbjct: 6 TLNTGASLELVGYGTWQAAPG-EVGQGVKVAIETGYRHLDLAKVYSNQPEVGAAIKEA-- 62 Query: 429 KYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLD---- 596 +KR D+FI SKL ++ V E A +TL LGL+Y+DLYL+H P + + Sbjct: 63 --GVKREDLFITSKLWNNSHRPEQV-EPALDDTLKELGLEYLDLYLIHWPVAFPPEGDIT 119 Query: 597 ---FENRNSSRIR-------KQTWATLVDLYHDHKIRALGVSNY 698 F N ++ TW +V L K++A+GVSN+ Sbjct: 120 QNLFPKANDKEVKLDLEVSLVDTWKAMVKLLDTGKVKAIGVSNF 163 >UniRef50_Q14LU6 Cluster: Putative aldo/keto reductase oxidoreductase protein; n=1; Spiroplasma citri|Rep: Putative aldo/keto reductase oxidoreductase protein - Spiroplasma citri Length = 138 Score = 72.5 bits (170), Expect = 3e-11 Identities = 45/112 (40%), Positives = 60/112 (53%) Frame = +3 Query: 234 LPQQFTLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAF 413 L + L NGVE+P IGL T+KM + V Q + AL+ GYR DTA +YGNE + A Sbjct: 4 LTTKLKLFNGVEIPLIGLGTYKMTDEHEVYQAIITALQNGYRHIDTAQIYGNEELIGKAI 63 Query: 414 KKLLPKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLV 569 K + R +IF+ SK+ N+ A + N L L DY+DL LV Sbjct: 64 K----DSGVPRKEIFLTSKIWNANHKYDAALQE-IDNILKRLDTDYLDLCLV 110 >UniRef50_Q41399 Cluster: Chalcone reductase; n=4; eudicotyledons|Rep: Chalcone reductase - Sesbania rostrata Length = 322 Score = 72.5 bits (170), Expect = 3e-11 Identities = 50/159 (31%), Positives = 83/159 (52%), Gaps = 10/159 (6%) Frame = +3 Query: 252 LNNGVEMPAIGLDT-FKMGHFYTVLQTVD-DALKAGYRMFDTAALYGNEVYLNFAFKKLL 425 LN+G +MP IG+ T + VL ++ DA++ GYR FD+A++YG E + A K + Sbjct: 11 LNSGHKMPVIGMGTSVESRPSNDVLASIFVDAIQVGYRHFDSASVYGTEEAIGMAVSKAI 70 Query: 426 PKYKLK-RGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLDFE 602 + +K R ++FI SK + + A TL LG++Y+DLYL+H P + D E Sbjct: 71 EQGLIKSRDEVFITSKPWNTDAHHDLIVP-ALKTTLKKLGMEYVDLYLIHWPVRLRHDLE 129 Query: 603 NR---NSSRIR----KQTWATLVDLYHDHKIRALGVSNY 698 N + + + TW + + Y +++G+ NY Sbjct: 130 NPVIFSKEDLLPFDIEGTWKAMEECYRLGLAKSIGICNY 168 >UniRef50_Q6CFG7 Cluster: Yarrowia lipolytica chromosome B of strain CLIB122 of Yarrowia lipolytica; n=9; Ascomycota|Rep: Yarrowia lipolytica chromosome B of strain CLIB122 of Yarrowia lipolytica - Yarrowia lipolytica (Candida lipolytica) Length = 337 Score = 72.5 bits (170), Expect = 3e-11 Identities = 57/166 (34%), Positives = 84/166 (50%), Gaps = 13/166 (7%) Frame = +3 Query: 246 FTLNNGVEMPAIGLDTFKMGHFYTVLQTVDDAL-KAGYRMFDTAALYGNEVYLNFAFKKL 422 FTLNNG +PAIGL T+K V V+ AL + GYR DTA Y NE + K+ Sbjct: 34 FTLNNGKTIPAIGLGTWK-STTEEVAGAVECALTEGGYRHIDTAFNYRNEDAVGLGIKRA 92 Query: 423 LPKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVH-----NPG-- 581 + K +KR DIF+ +K+ + E +L LGLDY+D+ L+H NP Sbjct: 93 MEK-GVKREDIFVTTKIWVTYHDR---VEENLDMSLERLGLDYVDMLLIHWPVPLNPNGN 148 Query: 582 --IYKL---DFENRNSSRIRKQTWATLVDLYHDHKIRALGVSNYFI 704 +Y L + + S + +TW + + K +++GVSN+ I Sbjct: 149 DPVYPLRPDGSRDIDESGSQPKTWKQMEAVLKTGKTKSIGVSNFSI 194 >UniRef50_A4YQ04 Cluster: 2,5-diketo-D-gluconate reductase B; n=15; Proteobacteria|Rep: 2,5-diketo-D-gluconate reductase B - Bradyrhizobium sp. (strain ORS278) Length = 273 Score = 72.1 bits (169), Expect = 3e-11 Identities = 51/149 (34%), Positives = 77/149 (51%), Gaps = 1/149 (0%) Frame = +3 Query: 261 GVEMPAIGLDTFKMGHFYTVLQ-TVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPKYK 437 GV +P +GL TF+M TV + V+ AL GYR DTA +Y NE + A L + Sbjct: 8 GVRLPKLGLGTFRMQG--TVCRDAVESALALGYRHIDTAEMYANEDAIGAA----LAAAQ 61 Query: 438 LKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLDFENRNSS 617 + R D+ + +K+ P N A+ RAF +L L LD++DLYL+H P + Sbjct: 62 IAREDLHVTTKVWPENLAPDAI-RRAFDTSLKKLRLDFVDLYLIHWPA----------TG 110 Query: 618 RIRKQTWATLVDLYHDHKIRALGVSNYFI 704 TL+ L + + RA+GV+N+ + Sbjct: 111 MNLPAAMETLMALKQEGRTRAIGVANFTV 139 >UniRef50_A1UEC5 Cluster: 2,5-didehydrogluconate reductase; n=20; Corynebacterineae|Rep: 2,5-didehydrogluconate reductase - Mycobacterium sp. (strain KMS) Length = 283 Score = 72.1 bits (169), Expect = 3e-11 Identities = 49/150 (32%), Positives = 79/150 (52%) Frame = +3 Query: 249 TLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLP 428 +LN+G +P +GL ++ ++V AL+AGYR+ DTAA+YGNE A + + Sbjct: 15 SLNDGHSIPVLGLGVGELSEAEAE-RSVAAALEAGYRLIDTAAVYGNEA----AVGRAVN 69 Query: 429 KYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLDFENR 608 + R +I++ +KL + G G ++ A +L LGLDY+DLYL+H P Sbjct: 70 ASGIPREEIYVTTKLAVADQGFG-TSQDAARASLERLGLDYVDLYLIHWPA-------GD 121 Query: 609 NSSRIRKQTWATLVDLYHDHKIRALGVSNY 698 + I +W L+ D R++GV N+ Sbjct: 122 HGKYI--DSWGGLMKAKQDGVARSIGVCNF 149 >UniRef50_Q5KI95 Cluster: Aldo-keto reductase, putative; n=14; Dikarya|Rep: Aldo-keto reductase, putative - Cryptococcus neoformans (Filobasidiella neoformans) Length = 353 Score = 72.1 bits (169), Expect = 3e-11 Identities = 57/165 (34%), Positives = 78/165 (47%), Gaps = 12/165 (7%) Frame = +3 Query: 237 PQQFTLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFK 416 P F LN G +PAIGL T++ V Q V ALKAGYR D A Y NE + K Sbjct: 36 PTSFKLNTGASIPAIGLGTWQ-AKAGEVRQAVAHALKAGYRHIDGALCYQNEDEVGLGIK 94 Query: 417 KLLPKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNP------ 578 + R +IF+ SK+ + E TL +L DY+DLYL+H P Sbjct: 95 DS----GVPRSEIFLTSKVWSSYHDR---VEECLDTTLKSLQTDYLDLYLIHWPVRLAPN 147 Query: 579 GIYKLDFENRNSSR------IRKQTWATLVDLYHDHKIRALGVSN 695 G + L + SR + +TWA + D+ K +A+G+SN Sbjct: 148 GTHPLFPVKPDGSRNLDWDWDQAKTWAQMEDVLKKGKAKAIGLSN 192 >UniRef50_UPI00015B40FA Cluster: PREDICTED: similar to CG2767-PA; n=2; Nasonia vitripennis|Rep: PREDICTED: similar to CG2767-PA - Nasonia vitripennis Length = 356 Score = 71.7 bits (168), Expect = 5e-11 Identities = 45/115 (39%), Positives = 63/115 (54%) Frame = +3 Query: 252 LNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPK 431 L++G +MP IGL T++M + V AL++GYR DTA YGNE + KK K Sbjct: 30 LSSGHDMPMIGLGTWQMPP-EAIEVAVTAALESGYRHIDTAFTYGNEEAIGKTLKKWFDK 88 Query: 432 YKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLD 596 KR D+FI +KL P V E +L LGL+Y+++YL+H P + D Sbjct: 89 GG-KREDLFITTKLPPIGMRAEYV-ESYLKLSLEKLGLEYVNMYLIHKPFAFVKD 141 >UniRef50_Q1YPE5 Cluster: Aldehyde reductase; n=7; Bacteria|Rep: Aldehyde reductase - gamma proteobacterium HTCC2207 Length = 330 Score = 71.7 bits (168), Expect = 5e-11 Identities = 43/114 (37%), Positives = 64/114 (56%), Gaps = 1/114 (0%) Frame = +3 Query: 270 MPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPKYKLKRG 449 MPA+GL +K+ + Q V +A+K GYR D+AA YGNE + + + + R Sbjct: 17 MPAVGLGLWKITQD-SAAQAVYEAIKVGYRHLDSAADYGNEQQVGEGIARAIAEGLCSRE 75 Query: 450 DIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNP-GIYKLDFENR 608 +++I +KL Y E A ++ +LGLDYIDLYLVH P + +DF +R Sbjct: 76 ELWITTKLWN-TYHRAEHVEAACRRSMDDLGLDYIDLYLVHFPIALRYVDFNDR 128 >UniRef50_A0JRJ3 Cluster: 2,5-didehydrogluconate reductase; n=3; Actinobacteria (class)|Rep: 2,5-didehydrogluconate reductase - Arthrobacter sp. (strain FB24) Length = 276 Score = 71.7 bits (168), Expect = 5e-11 Identities = 51/149 (34%), Positives = 75/149 (50%) Frame = +3 Query: 252 LNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPK 431 LN+G +P IGL T+ + + V V +A++ GYR DTA YGNE + + Sbjct: 9 LNDGHRIPQIGLGTWPLDD-HQVAAAVVNAVEGGYRHIDTAVKYGNEKGVGNGIR----S 63 Query: 432 YKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLDFENRN 611 L R ++FI +K L + G +L LGLDY+DL L+H P + +F + Sbjct: 64 SGLDRSELFITTK-LDGEFQGQDRAVAGLDGSLKRLGLDYVDLLLIHWPLPRRDEFIS-- 120 Query: 612 SSRIRKQTWATLVDLYHDHKIRALGVSNY 698 TW T L D K+R++GVSN+ Sbjct: 121 -------TWKTFERLQADGKVRSIGVSNF 142 >UniRef50_A7RRF6 Cluster: Predicted protein; n=2; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 275 Score = 71.3 bits (167), Expect = 6e-11 Identities = 40/110 (36%), Positives = 67/110 (60%) Frame = +3 Query: 249 TLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLP 428 TL++G ++P GL + + +T Q V AL+ GYRM DTAA Y NE + A ++ Sbjct: 8 TLSDGYKIPRFGLGLYDLDEKHTK-QAVLWALENGYRMIDTAASYNNEKRVGEALRESA- 65 Query: 429 KYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNP 578 + R ++++++K+ ++G T +A+ +LS LG+DY+DLYL+H P Sbjct: 66 ---VPRSEVYLVTKVYHTDHGYEK-TMKAYDRSLSALGVDYVDLYLIHFP 111 >UniRef50_P28475 Cluster: NADP-dependent D-sorbitol-6-phosphate dehydrogenase; n=71; Magnoliophyta|Rep: NADP-dependent D-sorbitol-6-phosphate dehydrogenase - Malus domestica (Apple) (Malus sylvestris) Length = 310 Score = 70.9 bits (166), Expect = 8e-11 Identities = 53/163 (32%), Positives = 84/163 (51%), Gaps = 13/163 (7%) Frame = +3 Query: 249 TLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLP 428 TL++G EMP IGL +++ + + + +A+K GYR FD AA Y +E + A + Sbjct: 5 TLSSGYEMPVIGLGLWRLEKD-ELKEVILNAIKIGYRHFDCAAHYKSEADVGEALAEAFK 63 Query: 429 KYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLDFENR 608 +KR ++FI +K+ N G V E A N+L L +DY+DLYLVH P K + + Sbjct: 64 TGLVKREELFITTKI--WNSDHGHVVE-ACKNSLEKLQIDYLDLYLVHYPMPTKHNAIGK 120 Query: 609 NSSRI-------------RKQTWATLVDLYHDHKIRALGVSNY 698 +S + +QTW + +R++G+SNY Sbjct: 121 TASLLGEDKVLDIDVTISLQQTWEGMEKTVSLGLVRSIGLSNY 163 >UniRef50_P23901 Cluster: Aldose reductase; n=9; Poaceae|Rep: Aldose reductase - Hordeum vulgare (Barley) Length = 320 Score = 70.9 bits (166), Expect = 8e-11 Identities = 53/159 (33%), Positives = 77/159 (48%), Gaps = 6/159 (3%) Frame = +3 Query: 246 FTLNNGVEMPAIGLDTFKMGHFYTVLQTVDDAL-KAGYRMFDTAALYGNEVYLNFAFKKL 422 F L +G MPA+GL T++ G +V A+ +AGYR DTAA YG E + K Sbjct: 16 FVLKSGHAMPAVGLGTWRAGS--DTAHSVRTAITEAGYRHVDTAAEYGVEKEVGKGLKAA 73 Query: 423 LPKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNP-----GIY 587 + + + R D+F+ SK+ N V A NTL +L LDYIDLY +H P G + Sbjct: 74 M-EAGIDRKDLFVTSKIWCTNLAPERVRP-ALENTLKDLQLDYIDLYHIHWPFRLKDGAH 131 Query: 588 KLDFENRNSSRIRKQTWATLVDLYHDHKIRALGVSNYFI 704 + W + +L D ++ +GV NY + Sbjct: 132 MPPEAGEVLEFDMEGVWKEMENLVKDGLVKDIGVCNYTV 170 >UniRef50_Q5KCN9 Cluster: Putative uncharacterized protein; n=1; Filobasidiella neoformans|Rep: Putative uncharacterized protein - Cryptococcus neoformans (Filobasidiella neoformans) Length = 295 Score = 70.1 bits (164), Expect = 1e-10 Identities = 47/155 (30%), Positives = 80/155 (51%), Gaps = 5/155 (3%) Frame = +3 Query: 249 TLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLP 428 TLN+GV++P IG + ++ + ALK GY D A +Y N + + K L Sbjct: 7 TLNDGVKIPKIGFGLGTTHYAKECVEHLVSALKTGYTYIDCAQMYKN----SKSVKDALE 62 Query: 429 KYKLKRGDIFIISKLLPCNYGGG-AVTER----AFHNTLSNLGLDYIDLYLVHNPGIYKL 593 K+ KR DIF++ K C GGG + +E+ L +G+DY+DLYL+H+P ++ Sbjct: 63 KWGGKREDIFLLQK---CGSGGGDSESEKNPKVILKGLLQEMGVDYVDLYLLHSPLLFAP 119 Query: 594 DFENRNSSRIRKQTWATLVDLYHDHKIRALGVSNY 698 + + WA + ++ + +++GVSN+ Sbjct: 120 KYS-------INEAWAIMEEIKSEGLAKSIGVSNF 147 >UniRef50_A2QL02 Cluster: Putative frameshift; n=1; Aspergillus niger|Rep: Putative frameshift - Aspergillus niger Length = 357 Score = 70.1 bits (164), Expect = 1e-10 Identities = 54/160 (33%), Positives = 80/160 (50%), Gaps = 9/160 (5%) Frame = +3 Query: 246 FTLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLL 425 +TLN G ++PA+G+ TF+ +TV L+ G R+ DTA +YG E + K Sbjct: 38 YTLNTGAKIPALGVGTFQDPDSQE--ETVCQVLQRGMRLIDTARVYGVEQQVGRGIK--- 92 Query: 426 PKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYK----- 590 K + R +IF+ +KL CN ERA ++L +L Y+DL L+H P +K Sbjct: 93 -KSGVPREEIFLGTKLW-CNDFHPDDVERAVDDSLRDLYTPYVDLLLMHYPCTFKRGEDR 150 Query: 591 --LDFENR--NSSRIRKQTWATLVDLYHDHKIRALGVSNY 698 D E R + TW L + K+RA+GVSN+ Sbjct: 151 FPRDAEGRMIHGETTFVDTWRALEKVVKTGKVRAIGVSNF 190 >UniRef50_UPI0000E4A7CE Cluster: PREDICTED: similar to LOC553452 protein; n=6; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to LOC553452 protein - Strongylocentrotus purpuratus Length = 321 Score = 69.7 bits (163), Expect = 2e-10 Identities = 49/161 (30%), Positives = 81/161 (50%), Gaps = 10/161 (6%) Frame = +3 Query: 252 LNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPK 431 L G ++P +G T+++ V + ++ A+ GYR D A+LYGNE + K + Sbjct: 10 LPGGRKLPLLGFGTWQIKP-EEVGRVIETAIDCGYRHIDEASLYGNEKGVGDGIKAKIDD 68 Query: 432 YKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNP-------GIYK 590 +KR D+F+ SKL + V E + +LS+LGL Y+DL+L+H P G + Sbjct: 69 GTIKREDLFVTSKLWVTDSHPSRV-EPSCRQSLSDLGLAYLDLFLIHCPTSAVGGKGPFP 127 Query: 591 LDFEN---RNSSRIRKQTWATLVDLYHDHKIRALGVSNYFI 704 +D + + TW + L +RA+GVSN+ + Sbjct: 128 MDDNGLFIGDDTIDYVDTWRIMESLVDKGLVRAIGVSNFTV 168 >UniRef50_UPI000023D0F1 Cluster: hypothetical protein FG03517.1; n=1; Gibberella zeae PH-1|Rep: hypothetical protein FG03517.1 - Gibberella zeae PH-1 Length = 364 Score = 69.7 bits (163), Expect = 2e-10 Identities = 46/153 (30%), Positives = 79/153 (51%), Gaps = 1/153 (0%) Frame = +3 Query: 243 QFTLNNGV-EMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKK 419 +F N V ++PA GL T+ G V+ V+ ALK GYR DTA ++ NE + K Sbjct: 50 EFNKNETVRDIPAFGLGTWLAGKG-VVVPAVEYALKGGYRHIDTALIWRNEDEVGKGIKA 108 Query: 420 LLPKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLDF 599 + R +I++ KL ++ V +A +++NLG++Y+DLYL+H P + + Sbjct: 109 S----GVSRDEIWVTGKLWNTDHRPELV-RKAIETSIANLGVEYLDLYLIHYPVAWVPET 163 Query: 600 ENRNSSRIRKQTWATLVDLYHDHKIRALGVSNY 698 + +++ TW + +L R +G SN+ Sbjct: 164 RDVDNNTSLIDTWKAMEELVRAGLTRNIGFSNF 196 >UniRef50_A3U9Y0 Cluster: Aldehyde reductase; n=5; Bacteroidetes|Rep: Aldehyde reductase - Croceibacter atlanticus HTCC2559 Length = 316 Score = 69.7 bits (163), Expect = 2e-10 Identities = 45/111 (40%), Positives = 61/111 (54%) Frame = +3 Query: 258 NGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPKYK 437 +G +P+IGL T+K V + V AL+ GY+ D AA Y NE + AFK+ Sbjct: 8 DGDSIPSIGLGTWKSDP-EDVKKAVKIALENGYKHIDCAAAYDNEDAVGEAFKESFESGN 66 Query: 438 LKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYK 590 +KR DIF+ SKL + V A TL +L LDY+DLYL+H P +K Sbjct: 67 VKREDIFVTSKLWNNAHKKEDVIP-ALKKTLKDLNLDYLDLYLMHWPVAFK 116 >UniRef50_Q9NAI5 Cluster: Putative uncharacterized protein; n=3; Caenorhabditis|Rep: Putative uncharacterized protein - Caenorhabditis elegans Length = 316 Score = 69.7 bits (163), Expect = 2e-10 Identities = 53/164 (32%), Positives = 81/164 (49%), Gaps = 11/164 (6%) Frame = +3 Query: 240 QQFTLNNGVEMPAIGLDTF--KMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAF 413 Q LN+G +PAIGL T+ K G ++T A+ AGYR D A +Y N+ + A Sbjct: 3 QSLKLNSGYSIPAIGLGTWQSKPGEVAAAIKT---AVAAGYRHIDCAHVYQNQKEVGEAL 59 Query: 414 KKLLPKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKL 593 K++L + K+KR ++FI SK+ + A LS+L L Y+DL L+H P Y Sbjct: 60 KEILDEGKVKREELFITSKVWN-TFHSEAKAHENIDIILSDLQLSYVDLMLIHWPQGYAE 118 Query: 594 D---FENRNSSRIR------KQTWATLVDLYHDHKIRALGVSNY 698 F + ++R +TW K R++G+SN+ Sbjct: 119 GAELFPAGENGKMRYSDVDYLETWKAFEAAQKAGKCRSIGLSNF 162 >UniRef50_Q2BBN7 Cluster: YvgN; n=1; Bacillus sp. NRRL B-14911|Rep: YvgN - Bacillus sp. NRRL B-14911 Length = 268 Score = 68.9 bits (161), Expect = 3e-10 Identities = 49/163 (30%), Positives = 74/163 (45%), Gaps = 10/163 (6%) Frame = +3 Query: 240 QQFTLNNGVEMPAIGLDTFKMGH--------FYTVLQTVDDALKAGYRMFDTAALYGNEV 395 + TLNNG+EMP +G T G + + A++ GYR D A +Y NE Sbjct: 2 EYITLNNGLEMPIVGTGTNTYGKENNDYNGDLTNEIPELASAIELGYRSIDAAIMYRNEE 61 Query: 396 YLNFAFKKLLPKYKLKRGDIFIISKLLPCN--YGGGAVTERAFHNTLSNLGLDYIDLYLV 569 + +L + K+ R + FI +K+ T A N+L N DY+DL L+ Sbjct: 62 LVG----SVLAESKVPREEFFITTKIPASEEYISSKEATRAAIDNSLKNFQTDYLDLLLI 117 Query: 570 HNPGIYKLDFENRNSSRIRKQTWATLVDLYHDHKIRALGVSNY 698 H P K+ +N TW + Y K++A+GVSN+ Sbjct: 118 HFPIEDKVQLKN---------TWEVFEEYYEAGKLKAIGVSNF 151 >UniRef50_Q75E75 Cluster: ABL209Cp; n=1; Eremothecium gossypii|Rep: ABL209Cp - Ashbya gossypii (Yeast) (Eremothecium gossypii) Length = 310 Score = 68.9 bits (161), Expect = 3e-10 Identities = 50/152 (32%), Positives = 81/152 (53%), Gaps = 3/152 (1%) Frame = +3 Query: 252 LNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPK 431 L++G ++P++GL +++ TV V +AL+ GYR+FD+A Y NE + L Sbjct: 15 LSDGTQIPSVGLGVYQVSE-QTVQDLVYEALEVGYRLFDSAQAYHNEDGVARGIAAWLKH 73 Query: 432 YK-LKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLG-LDYIDLYLVHNPGIYKLDFEN 605 +R D++ +K+ N+G A T+++ +L G L YIDL LVH P Sbjct: 74 APGRRREDVYFTTKINTQNHGYEA-TKKSLEKSLHAAGPLGYIDLVLVHAP--------- 123 Query: 606 RNSSRIRK-QTWATLVDLYHDHKIRALGVSNY 698 S R R+ TW L + + ++R++GVSNY Sbjct: 124 -MSDRTRRLGTWQALEEAVVEGQVRSIGVSNY 154 >UniRef50_A7EW94 Cluster: Putative uncharacterized protein; n=1; Sclerotinia sclerotiorum 1980|Rep: Putative uncharacterized protein - Sclerotinia sclerotiorum 1980 Length = 326 Score = 68.5 bits (160), Expect = 4e-10 Identities = 53/158 (33%), Positives = 75/158 (47%) Frame = +3 Query: 225 KYILPQQFTLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLN 404 K+ + + +N+G E+P +G ++ V A AGYR D+AA Y NE Sbjct: 39 KFNINSKLRMNSGYEIPILGYGVYQTPASQCE-DLVAKAFDAGYRHVDSAAAYRNEGPCA 97 Query: 405 FAFKKLLPKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGI 584 A ++ + R DIF SK+ P + T+ TL GL YIDL L+H P Sbjct: 98 AAIRRS----SIPREDIFFTSKIPPRSLSYEN-TKAQVAKTLMETGLGYIDLMLIHAP-- 150 Query: 585 YKLDFENRNSSRIRKQTWATLVDLYHDHKIRALGVSNY 698 + R + RK W LV+ + KIR+LGVSNY Sbjct: 151 ----YGGRAA---RKGAWKALVEAQEEGKIRSLGVSNY 181 >UniRef50_P06632 Cluster: 2,5-diketo-D-gluconic acid reductase A; n=8; Actinomycetales|Rep: 2,5-diketo-D-gluconic acid reductase A - Corynebacterium sp. (strain ATCC 31090) Length = 278 Score = 68.5 bits (160), Expect = 4e-10 Identities = 49/151 (32%), Positives = 77/151 (50%) Frame = +3 Query: 252 LNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPK 431 LN+G +P +G FK+ T + V++AL+ GYR DTAA+YGNE + A + Sbjct: 8 LNDGNSIPQLGYGVFKVPPADTQ-RAVEEALEVGYRHIDTAAIYGNEEGVGAA----IAA 62 Query: 432 YKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLDFENRN 611 + R D+FI +KL + G A +L+ L LD +DLYLVH P ++ + Sbjct: 63 SGIARDDLFITTKLWNDRHDGDE-PAAAIAESLAKLALDQVDLYLVHWPTPAADNYVH-- 119 Query: 612 SSRIRKQTWATLVDLYHDHKIRALGVSNYFI 704 W +++L R++GVSN+ + Sbjct: 120 -------AWEKMIELRAAGLTRSIGVSNHLV 143 >UniRef50_UPI0000D56CE5 Cluster: PREDICTED: similar to CG6084-PA, isoform A; n=1; Tribolium castaneum|Rep: PREDICTED: similar to CG6084-PA, isoform A - Tribolium castaneum Length = 493 Score = 68.1 bits (159), Expect = 6e-10 Identities = 46/149 (30%), Positives = 79/149 (53%) Frame = +3 Query: 252 LNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPK 431 LNNG+E+P GL + F+ V + V + + YR+ D +++ NE A ++L+ Sbjct: 13 LNNGIEIPVFGLAAPQ--DFFEV-ENVQLVVSSNYRLMD-CSIFENEKRFGVALQQLIEG 68 Query: 432 YKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLDFENRN 611 K++R D+F++SK C + + A +TL L + Y+DLYL+ P K + Sbjct: 69 GKIRRKDLFLMSKF--CCTNTTNLVKAALLDTLKKLQVAYLDLYLIERPPACK------D 120 Query: 612 SSRIRKQTWATLVDLYHDHKIRALGVSNY 698 + I +TW + LY + RA+G+SN+ Sbjct: 121 HNLI--ETWEAMEGLYSEKLTRAIGLSNF 147 >UniRef50_Q0VGY1 Cluster: 3-alpha-hydroxysteroid dehydrogenase; n=13; Tetrapoda|Rep: 3-alpha-hydroxysteroid dehydrogenase - Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) Length = 324 Score = 68.1 bits (159), Expect = 6e-10 Identities = 51/160 (31%), Positives = 76/160 (47%), Gaps = 11/160 (6%) Frame = +3 Query: 252 LNNGVEMPAIGLDTFKMGHFYTVL--QTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLL 425 LN+G +MP IG T+ F L + A+ GYR D A LYGNE + A + + Sbjct: 11 LNDGHKMPVIGFGTYAPPKFPKSLAEEGTKVAIDVGYRHIDCAFLYGNEEEVGRAIRAKI 70 Query: 426 PKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYK----L 593 +KR D+F KL ++ V A +L +L LDY+DL+++H P +K L Sbjct: 71 ADGTVKREDVFYTGKLWSTSHTPERV-RPALEKSLKDLQLDYMDLFIIHMPMEFKPGDDL 129 Query: 594 DFENRNSSRI-----RKQTWATLVDLYHDHKIRALGVSNY 698 + N I + TW L +R++GVSN+ Sbjct: 130 FPADENGKFIYHNTDLRDTWKALEKCKDAGLVRSIGVSNF 169 >UniRef50_Q9FJK0 Cluster: Aldose reductase-like protein; n=3; core eudicotyledons|Rep: Aldose reductase-like protein - Arabidopsis thaliana (Mouse-ear cress) Length = 316 Score = 68.1 bits (159), Expect = 6e-10 Identities = 48/157 (30%), Positives = 78/157 (49%), Gaps = 8/157 (5%) Frame = +3 Query: 252 LNNGVEMPAIGLDTF-KMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLP 428 L G +P +G+ T+ + + V A+K GYR FDTA +YG+E L A + + Sbjct: 8 LRCGETIPLLGMGTYCPQKDRESTISAVHQAIKIGYRHFDTAKIYGSEEALGTALGQAIS 67 Query: 429 KYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVH-----NPGIYK- 590 ++R D+F+ SKL ++ A TL +GLDY+D YLVH PG+ + Sbjct: 68 YGTVQRDDLFVTSKLWSSDHHDPI---SALIQTLKTMGLDYLDNYLVHWPIKLKPGVSEP 124 Query: 591 LDFENRNSSRIR-KQTWATLVDLYHDHKIRALGVSNY 698 + E+ + ++TW + R++GVSN+ Sbjct: 125 IPKEDEFEKDLGIEETWQGMERCLEMGLCRSIGVSNF 161 >UniRef50_Q8G7K9 Cluster: Dehydrogenase or reductase protein; n=4; Bifidobacterium|Rep: Dehydrogenase or reductase protein - Bifidobacterium longum Length = 289 Score = 67.7 bits (158), Expect = 8e-10 Identities = 48/149 (32%), Positives = 73/149 (48%) Frame = +3 Query: 252 LNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPK 431 L +G +P +GL ++ V+ V+ AL+AGYR D AA Y NE + A Sbjct: 16 LKDGHSIPQVGLGVLRIDD-EGVVPVVESALEAGYRHIDGAAGYNNEAGVGRALAASGYN 74 Query: 432 YKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLDFENRN 611 KR +++ +KL G + +AF N+L L LDY+D+Y++H P F+ R+ Sbjct: 75 KGAKRETLWVTTKLRDSQQGYDSAL-KAFDNSLKLLQLDYVDMYMIHWP----TPFDWRS 129 Query: 612 SSRIRKQTWATLVDLYHDHKIRALGVSNY 698 + TW V L + R LGV N+ Sbjct: 130 T-----DTWKAFVKLRDEGMARTLGVCNF 153 >UniRef50_Q7ZWA4 Cluster: Zgc:56622; n=6; cellular organisms|Rep: Zgc:56622 - Danio rerio (Zebrafish) (Brachydanio rerio) Length = 289 Score = 67.3 bits (157), Expect = 1e-09 Identities = 44/129 (34%), Positives = 70/129 (54%), Gaps = 9/129 (6%) Frame = +3 Query: 339 ALKAGYRMFDTAALYGNEVYLNFAFKKLLPKYKLKRGDIFIISKLLPCNYGGGAVTERAF 518 A+ AGYR DTA Y NEV + A + + + ++R D+FI+SKL ++ + F Sbjct: 9 AIAAGYRHIDTAFCYRNEVDVGMAIQNKIQQGIIRRQDMFIVSKLWGTHHAPEDIPV-CF 67 Query: 519 HNTLSNLGLDYIDLYLVHNP-GIYKLD---FENRNSSRIRK-----QTWATLVDLYHDHK 671 + +LS+L LDY+D YLVH P G+ K+ F R+ + W + L K Sbjct: 68 NKSLSDLQLDYLDQYLVHFPVGLKKVGDELFPERDGKILTTDIDYVDVWRGMEALKATGK 127 Query: 672 IRALGVSNY 698 ++++GVSN+ Sbjct: 128 VKSIGVSNF 136 >UniRef50_Q7QK25 Cluster: ENSANGP00000019775; n=2; Anopheles gambiae str. PEST|Rep: ENSANGP00000019775 - Anopheles gambiae str. PEST Length = 319 Score = 67.3 bits (157), Expect = 1e-09 Identities = 37/108 (34%), Positives = 60/108 (55%) Frame = +3 Query: 255 NNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPKY 434 +NG E+P +G T+ + ++ V A+ GYR DTA LY NEV + A + + + Sbjct: 11 SNGYEIPVLGYGTY-LAQKGQCVELVKKAIDLGYRHIDTAFLYENEVEIGQAIRDKIAEG 69 Query: 435 KLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNP 578 ++R D+F+ +KL + V E AF + L + YIDL+L+H+P Sbjct: 70 VIRREDVFVTTKLWNTFHDPQHV-EEAFRRSFDMLDIGYIDLFLMHSP 116 >UniRef50_Q4JX70 Cluster: Putative oxidoreductase; n=1; Corynebacterium jeikeium K411|Rep: Putative oxidoreductase - Corynebacterium jeikeium (strain K411) Length = 285 Score = 66.9 bits (156), Expect = 1e-09 Identities = 38/109 (34%), Positives = 61/109 (55%) Frame = +3 Query: 252 LNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPK 431 +N+G P +GL +++ T +V A++ GYR DTAA+YGNE + A + Sbjct: 13 MNDGKTTPQLGLGVWQLSDEDTYT-SVRAAIETGYRHIDTAAIYGNEEAVGRAVADAVKA 71 Query: 432 YKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNP 578 ++R ++FI +KL + G + AF + LG+DY+DLYL+H P Sbjct: 72 GDVQREELFITTKLWNADQACG---KEAFAESQKKLGMDYVDLYLLHWP 117 >UniRef50_Q01HB5 Cluster: OSIGBa0136O08-OSIGBa0153H12.9 protein; n=4; Oryza sativa|Rep: OSIGBa0136O08-OSIGBa0153H12.9 protein - Oryza sativa (Rice) Length = 337 Score = 66.9 bits (156), Expect = 1e-09 Identities = 40/111 (36%), Positives = 60/111 (54%), Gaps = 1/111 (0%) Frame = +3 Query: 249 TLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLP 428 TLN+G MP +G T + T+ A++ GYR DTAA+YG E + A + + Sbjct: 24 TLNSGHAMPVLGFGTGSSTPPADLAATIAHAVRLGYRHLDTAAVYGTEGAVGAAVAEAVR 83 Query: 429 KYKL-KRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNP 578 + RG++F+ +KL + V A +LS LGLDY+DL+L+H P Sbjct: 84 CGAVASRGELFVTTKLSMADAHPPRVVA-ALRESLSRLGLDYVDLFLIHWP 133 >UniRef50_A7SGW6 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 264 Score = 66.9 bits (156), Expect = 1e-09 Identities = 53/151 (35%), Positives = 78/151 (51%), Gaps = 1/151 (0%) Frame = +3 Query: 249 TLNNGVEMPAIGLDTFKMGHFYTVLQTVD-DALKAGYRMFDTAALYGNEVYLNFAFKKLL 425 TLN+G +MP GL F++ T + V ALK GYRM DTA +Y NE + A + Sbjct: 14 TLNDGRKMPLFGLGVFRLE---TGCEDVCLFALKNGYRMLDTADIYQNEKEVGSAVR--- 67 Query: 426 PKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLDFEN 605 K LKR DI++ +KL P G + A ++ L + Y+DL+L+H P Sbjct: 68 -KSGLKREDIYVTTKLKPSEEGHSNALKYA-KESIKKLDIGYVDLFLIHTP--------- 116 Query: 606 RNSSRIRKQTWATLVDLYHDHKIRALGVSNY 698 R + I + L+ L + IR++GVSN+ Sbjct: 117 RPGNII--AAYDALLTLKEEGLIRSVGVSNF 145 >UniRef50_Q7G765 Cluster: Probable NAD(P)H-dependent oxidoreductase 2; n=6; Magnoliophyta|Rep: Probable NAD(P)H-dependent oxidoreductase 2 - Oryza sativa subsp. japonica (Rice) Length = 322 Score = 66.9 bits (156), Expect = 1e-09 Identities = 51/153 (33%), Positives = 73/153 (47%), Gaps = 10/153 (6%) Frame = +3 Query: 270 MPAIGLDT--FKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPKYKL- 440 MP IG+ T F + A++ GYR FDTA LY E ++ A + + + + Sbjct: 18 MPRIGMGTAAFPFTSSEETTAALLRAIELGYRHFDTARLYATEGCVSEAVAEAVRRGLVA 77 Query: 441 KRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVH-----NPGIYKLDF-- 599 R D+F+ SKL + G V A TL NLG+DY+DL LVH PG Y F Sbjct: 78 SRADVFVTSKLWCSDLHAGRVVPAA-RETLRNLGMDYVDLLLVHWPATVAPGSYDFPFPK 136 Query: 600 ENRNSSRIRKQTWATLVDLYHDHKIRALGVSNY 698 E + + W + + + RA+GVSN+ Sbjct: 137 EEMAPAFDMEGVWRGMEECHRLGLARAIGVSNF 169 >UniRef50_Q5FK99 Cluster: Oxidoreductase aldo-keto reductase family; n=5; Lactobacillus|Rep: Oxidoreductase aldo-keto reductase family - Lactobacillus acidophilus Length = 289 Score = 66.5 bits (155), Expect = 2e-09 Identities = 46/150 (30%), Positives = 72/150 (48%) Frame = +3 Query: 252 LNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPK 431 LN+G E+P +G F++ + ++ V+ A+ GYR+ DTA Y N+ + A K Sbjct: 9 LNDGNEIPQLGFGVFQISNHDEAVKAVESAISNGYRLIDTAEAYNNQTAVGEAIK----N 64 Query: 432 YKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLDFENRN 611 + R DIF+ +KL N+ + +A L LG DYID+ L+H Y D Sbjct: 65 SDVNRDDIFLTTKLWVSNFTYEKAS-KAIDEDLKELGTDYIDMMLLHQ--AYG-DVAG-- 118 Query: 612 SSRIRKQTWATLVDLYHDHKIRALGVSNYF 701 W L D K +++GVSN++ Sbjct: 119 -------AWRALEDAQKAGKTKSIGVSNFW 141 >UniRef50_Q9P6D3 Cluster: Related to aldo-keto reductase YPR1; n=10; Pezizomycotina|Rep: Related to aldo-keto reductase YPR1 - Neurospora crassa Length = 322 Score = 66.5 bits (155), Expect = 2e-09 Identities = 43/122 (35%), Positives = 67/122 (54%) Frame = +3 Query: 339 ALKAGYRMFDTAALYGNEVYLNFAFKKLLPKYKLKRGDIFIISKLLPCNYGGGAVTERAF 518 AL AGY D A +YGNEV L A + + KL R ++I +K + G VT+ +F Sbjct: 67 ALNAGYAHLDGAEVYGNEVELGRA----IAQSKLPRSSLYITTKTIV--RAGDTVTQ-SF 119 Query: 519 HNTLSNLGLDYIDLYLVHNPGIYKLDFENRNSSRIRKQTWATLVDLYHDHKIRALGVSNY 698 + +L LGLDY+DLYL+H+P F +N ++ + W + + +++GVSN+ Sbjct: 120 NRSLEKLGLDYVDLYLLHSP------FFAKNPEQL-QAAWREMEKIKDSGMAKSIGVSNF 172 Query: 699 FI 704 I Sbjct: 173 LI 174 >UniRef50_Q0CLQ2 Cluster: Putative uncharacterized protein; n=1; Aspergillus terreus NIH2624|Rep: Putative uncharacterized protein - Aspergillus terreus (strain NIH 2624) Length = 301 Score = 66.5 bits (155), Expect = 2e-09 Identities = 44/110 (40%), Positives = 62/110 (56%) Frame = +3 Query: 240 QQFTLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKK 419 + F L++G +MPA+GL T+ + + V V+ AL+ GYR D AA Y NE + +KK Sbjct: 5 RSFKLSSGYDMPAVGLGTW-LSKPHEVENAVETALRLGYRHIDAAACYLNENEVGNGWKK 63 Query: 420 LLPKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLV 569 + R IFI SKL ++ V E A + TL +L DY+DLYLV Sbjct: 64 S----GVPRDQIFITSKLWNTHHHPDHV-EEAVNKTLKDLQTDYLDLYLV 108 >UniRef50_Q7N0E4 Cluster: 2,5-diketo-D-gluconic acid reductase A; n=2; Bacteria|Rep: 2,5-diketo-D-gluconic acid reductase A - Photorhabdus luminescens subsp. laumondii Length = 292 Score = 66.1 bits (154), Expect = 2e-09 Identities = 48/149 (32%), Positives = 73/149 (48%) Frame = +3 Query: 252 LNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPK 431 L +G MP +GL ++ + +T+ AL GYR DTAA+Y NE + A L + Sbjct: 9 LADGNHMPQLGLGSWASDD-QQIAETIHAALDIGYRAIDTAAIYNNEKGVGNA----LQE 63 Query: 432 YKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLDFENRN 611 + R DIF+ +KL + A +L L LDY+DLYL+H P + + Sbjct: 64 TDIPREDIFVTTKLWNDRH---LDARAALTESLEKLQLDYVDLYLIHWPAPPQDQYVG-- 118 Query: 612 SSRIRKQTWATLVDLYHDHKIRALGVSNY 698 W L++L + IR++GVSN+ Sbjct: 119 -------AWQQLIELQKEGLIRSIGVSNF 140 >UniRef50_Q7PCV3 Cluster: ENSANGP00000031808; n=9; Endopterygota|Rep: ENSANGP00000031808 - Anopheles gambiae str. PEST Length = 316 Score = 66.1 bits (154), Expect = 2e-09 Identities = 42/111 (37%), Positives = 57/111 (51%) Frame = +3 Query: 258 NGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPKYK 437 NG +P GL T+ V Q V DA+ GYR D A +Y NE + + + Sbjct: 13 NGNSIPMFGLGTWNSPPGQ-VAQAVKDAIDVGYRHIDCAHVYQNEHEVGEGIAAKIAEGV 71 Query: 438 LKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYK 590 +KR D+F+ SKL + + E A TL NL LDY+DLYL+H P Y+ Sbjct: 72 VKREDLFVTSKLWN-TFHRPDLVEGACKTTLQNLKLDYLDLYLIHWPVGYQ 121 >UniRef50_Q68ST9 Cluster: Reductase AKOR2; n=2; Pleurotus djamor|Rep: Reductase AKOR2 - Pleurotus djamor Length = 306 Score = 66.1 bits (154), Expect = 2e-09 Identities = 58/165 (35%), Positives = 79/165 (47%), Gaps = 14/165 (8%) Frame = +3 Query: 252 LNNGVEMPAIGLDTFKMGHFYTVLQTVD---DALKAGYRMFDTAALYGNEVYLNFAFKKL 422 LN G MPA+ L + Q + ALK+GYR DTA +Y E + A ++ Sbjct: 9 LNTGARMPALALGGWAGLTEEERTQAKEWFLTALKSGYRHIDTAQIYYTEKSVGNAIRES 68 Query: 423 LPKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPG--IY--K 590 + R ++FI +KL P N+ V E +F +L NLG +YIDLYLVH P Y Sbjct: 69 ----GIPREELFITTKL-PWNHHS-RVAE-SFQKSLENLGTEYIDLYLVHFPQRVFYDET 121 Query: 591 LDFENRNSSRIR-------KQTWATLVDLYHDHKIRALGVSNYFI 704 DF I+ WA + L K++A+GVSNY I Sbjct: 122 TDFPRNPDGSIKVVNSPTLNDVWADVETLLDTGKVKAIGVSNYSI 166 >UniRef50_Q96JD6-2 Cluster: Isoform 2 of Q96JD6 ; n=4; Catarrhini|Rep: Isoform 2 of Q96JD6 - Homo sapiens (Human) Length = 263 Score = 65.7 bits (153), Expect = 3e-09 Identities = 38/108 (35%), Positives = 61/108 (56%) Frame = +3 Query: 267 EMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPKYKLKR 446 ++PA+GL ++K V + V +A+ AGYR FD A Y NE + + + + ++R Sbjct: 3 DIPAVGLSSWKASPG-KVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEGAVRR 61 Query: 447 GDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYK 590 D+FI +KL C ++ E A +L L L+Y+DLYL+H P +K Sbjct: 62 EDLFIATKLW-CTCHKKSLVETACRKSLKALKLNYLDLYLIHWPMGFK 108 >UniRef50_Q83N50 Cluster: 2,5-diketo-D-gluconic acid reductase; n=2; Tropheryma whipplei|Rep: 2,5-diketo-D-gluconic acid reductase - Tropheryma whipplei (strain Twist) (Whipple's bacillus) Length = 283 Score = 65.7 bits (153), Expect = 3e-09 Identities = 46/149 (30%), Positives = 72/149 (48%) Frame = +3 Query: 252 LNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPK 431 L +GV +P GL T+++ V A++ GYR DTA+LY NE + A + Sbjct: 14 LGDGVSIPQFGLGTYELPP-NEASSVVQSAIELGYRHIDTASLYANEREVGRA----IAS 68 Query: 432 YKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLDFENRN 611 +KR + F+ +KL + AF +L L LDY+DLYL+H P Sbjct: 69 SGIKREEFFVTTKLWNSDQ---PKPREAFERSLDLLSLDYVDLYLIHWP---------CP 116 Query: 612 SSRIRKQTWATLVDLYHDHKIRALGVSNY 698 S + W L++L + +++GVSN+ Sbjct: 117 PSELYINVWEVLLELKESGRAKSVGVSNF 145 >UniRef50_Q572D2 Cluster: Aldo-keto reductase, putative; n=1; Phytophthora infestans|Rep: Aldo-keto reductase, putative - Phytophthora infestans (Potato late blight fungus) Length = 255 Score = 65.7 bits (153), Expect = 3e-09 Identities = 47/149 (31%), Positives = 69/149 (46%) Frame = +3 Query: 252 LNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPK 431 L +G +P IGL ++ + +LK GYR DTA +YGNE + A + Sbjct: 10 LPSGARIPMIGLGVYQSEPGPETYNAILTSLKLGYRHIDTAEIYGNEEDVGRAVR----D 65 Query: 432 YKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLDFENRN 611 + R +IF+ +KL N+G A + LG+ YI LYL+H PG Sbjct: 66 SGIPREEIFVTTKLFTTNWGYSKAL-AAGKASNDRLGIVYIYLYLLHAPG---------- 114 Query: 612 SSRIRKQTWATLVDLYHDHKIRALGVSNY 698 + R TW + DL +R +GVSN+ Sbjct: 115 PPKERADTWRAVEDLREQETLRDIGVSNF 143 >UniRef50_Q68A33 Cluster: Aldo-keto reductase 1a; n=1; Ciona intestinalis|Rep: Aldo-keto reductase 1a - Ciona intestinalis (Transparent sea squirt) Length = 584 Score = 65.7 bits (153), Expect = 3e-09 Identities = 50/162 (30%), Positives = 76/162 (46%), Gaps = 11/162 (6%) Frame = +3 Query: 252 LNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALY-GNEVYLNFAFK---- 416 LN+G MP IGL T ++ F +TV ALK GYRM DTA +Y G + NF Sbjct: 262 LNSGYMMPPIGLGTARL--FSKTYETVKTALKLGYRMLDTAQIYTGEDKINNFKVSSEEE 319 Query: 417 --KLLPKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVH----NP 578 + + + R ++FI++KL P + + +L L DYIDL L+H + Sbjct: 320 IGRAIADSDVPRSELFIVTKLAPESMEKENAIAKV-EESLKKLRTDYIDLLLIHDFYMST 378 Query: 579 GIYKLDFENRNSSRIRKQTWATLVDLYHDHKIRALGVSNYFI 704 D + W T+ ++ +R++GVSN +I Sbjct: 379 ACGPDDTDLPECKNNPFLAWKTMEEMQAKGLVRSIGVSNIYI 420 >UniRef50_Q96JD6 Cluster: Aldo-keto reductase family 1 member C-like protein 2; n=37; Euteleostomi|Rep: Aldo-keto reductase family 1 member C-like protein 2 - Homo sapiens (Human) Length = 320 Score = 65.7 bits (153), Expect = 3e-09 Identities = 38/108 (35%), Positives = 61/108 (56%) Frame = +3 Query: 267 EMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPKYKLKR 446 ++PA+GL ++K V + V +A+ AGYR FD A Y NE + + + + ++R Sbjct: 3 DIPAVGLSSWKASPG-KVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEGAVRR 61 Query: 447 GDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYK 590 D+FI +KL C ++ E A +L L L+Y+DLYL+H P +K Sbjct: 62 EDLFIATKLW-CTCHKKSLVETACRKSLKALKLNYLDLYLIHWPMGFK 108 >UniRef50_A5VK30 Cluster: 2,5-didehydrogluconate reductase; n=2; Lactobacillus reuteri|Rep: 2,5-didehydrogluconate reductase - Lactobacillus reuteri F275 Length = 300 Score = 65.3 bits (152), Expect = 4e-09 Identities = 46/155 (29%), Positives = 72/155 (46%) Frame = +3 Query: 234 LPQQFTLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAF 413 L + LNNG +P +GL +K T Q V +A+ Y + DTA YGNE + Sbjct: 9 LQPKIKLNNGHLIPQLGLGVWKASLAETQ-QMVKEAIMNDYVLIDTAKQYGNEAAVGQGI 67 Query: 414 KKLLPKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKL 593 + KR IF+ +K+ + G +A + L L +Y+DL L+H P K Sbjct: 68 QDGFKATGRKRDSIFLTTKIFNGDQGDYDKLRQAVNEQLKKLQTNYVDLLLLHWPVNDKY 127 Query: 594 DFENRNSSRIRKQTWATLVDLYHDHKIRALGVSNY 698 + ++W L D+Y D + +A+GV N+ Sbjct: 128 N-----------ESWRALEDIYKDGQAKAIGVCNF 151 >UniRef50_Q7XY49 Cluster: Mannose 6-phosphate reductase; n=1; Griffithsia japonica|Rep: Mannose 6-phosphate reductase - Griffithsia japonica (Red alga) Length = 174 Score = 65.3 bits (152), Expect = 4e-09 Identities = 41/112 (36%), Positives = 60/112 (53%) Frame = +3 Query: 249 TLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLP 428 TL +G +MP G T+K T Q V AL+AGYR D AA+Y NE + A K + Sbjct: 7 TLQSGAKMPLNGFGTWKASVEETE-QAVTAALRAGYRHIDCAAVYWNEAAVGTAISKAIS 65 Query: 429 KYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGI 584 +KR D+FI SK+ + V + + +L + +DY DL+LV + G+ Sbjct: 66 GGVVKREDLFITSKVWNTCHATDKVVD-SCRQSLKDHQVDYFDLFLVRDIGV 116 >UniRef50_Q7QVQ9 Cluster: GLP_302_44328_45269; n=1; Giardia lamblia ATCC 50803|Rep: GLP_302_44328_45269 - Giardia lamblia ATCC 50803 Length = 313 Score = 65.3 bits (152), Expect = 4e-09 Identities = 50/157 (31%), Positives = 77/157 (49%), Gaps = 13/157 (8%) Frame = +3 Query: 273 PAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPKYK--LKR 446 P +G T++ V V+ AL GYR D A +Y NE + AF K+ +KR Sbjct: 5 PRLGFGTWQAPP-EAVQTAVETALMTGYRHIDCAYVYQNEEAIGRAFGKIFKDASSGIKR 63 Query: 447 GDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNP---------GIYKLDF 599 D++I SKL N+ V E+ T+S+L +DY+DL+LVH P ++ D Sbjct: 64 EDVWITSKLWNYNHRPELVREQC-KKTMSDLQVDYLDLFLVHWPLAFVRNDVGDLFPKDA 122 Query: 600 ENRNS-SRI-RKQTWATLVDLYHDHKIRALGVSNYFI 704 E R ++ TW + L + ++ +GVSNY + Sbjct: 123 EGRAMLEKVPLADTWRAMEQLVEEGLVKHIGVSNYTV 159 >UniRef50_Q8J0K1 Cluster: 4-dihydromethyltrisporate dehydrogenase; n=2; Parasitella parasitica|Rep: 4-dihydromethyltrisporate dehydrogenase - Parasitella parasitica Length = 321 Score = 65.3 bits (152), Expect = 4e-09 Identities = 34/84 (40%), Positives = 49/84 (58%) Frame = +3 Query: 327 TVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPKYKLKRGDIFIISKLLPCNYGGGAVT 506 T+ A+K GYR+FD A YGNEV + K + + +KR ++FI++KL + V Sbjct: 33 TIYQAIKIGYRLFDGACDYGNEVEVGRGINKAIKEGLVKREELFIVTKLWNTFHSKQHV- 91 Query: 507 ERAFHNTLSNLGLDYIDLYLVHNP 578 AF L + GL+Y DLYL+H P Sbjct: 92 RTAFDRQLKDWGLEYFDLYLIHFP 115 >UniRef50_A5DRJ6 Cluster: Putative uncharacterized protein; n=4; Pichia guilliermondii|Rep: Putative uncharacterized protein - Pichia guilliermondii (Yeast) (Candida guilliermondii) Length = 287 Score = 65.3 bits (152), Expect = 4e-09 Identities = 49/153 (32%), Positives = 74/153 (48%), Gaps = 2/153 (1%) Frame = +3 Query: 246 FTLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLL 425 F L NG +PA G+ + + T V+ AL GYR+ DTA Y NE K L Sbjct: 10 FPLLNGSRIPACGVGVYLLPASQTA-GIVEKALDVGYRLIDTAQEYENERETGEGIKAWL 68 Query: 426 PKYK-LKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNL-GLDYIDLYLVHNPGIYKLDF 599 K K KR D+ +K+ N G T R+ +L+ + L+YIDL L+H+P Sbjct: 69 GKDKNNKREDVLYTTKITNLNQGYDR-TWRSLKESLNKVKHLEYIDLVLIHDP------- 120 Query: 600 ENRNSSRIRKQTWATLVDLYHDHKIRALGVSNY 698 + + R +TW L + ++++GVSN+ Sbjct: 121 --LSDKKTRIETWKALQEAVDSGMVKSIGVSNF 151 >UniRef50_P26690 Cluster: NAD(P)H-dependent 6'-deoxychalcone synthase; n=3; Papilionoideae|Rep: NAD(P)H-dependent 6'-deoxychalcone synthase - Glycine max (Soybean) Length = 315 Score = 65.3 bits (152), Expect = 4e-09 Identities = 43/133 (32%), Positives = 66/133 (49%), Gaps = 6/133 (4%) Frame = +3 Query: 324 QTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPKYKLKRGDIFIISKLLPCNYGGGAV 503 + + +A+K GYR FDTAA YG+E L A K+ + + R D+F+ SKL V Sbjct: 40 EAIIEAVKQGYRHFDTAAAYGSEQALGEALKEAIHLGLVSRQDLFVTSKLWVTENHPHLV 99 Query: 504 TERAFHNTLSNLGLDYIDLYLVH-----NPGIYKLDFENRNSSRIR-KQTWATLVDLYHD 665 A +L L L+Y+DLYL+H PG + E + K W ++ + Sbjct: 100 LP-ALRKSLKTLQLEYLDLYLIHWPLSSQPGKFSFPIEVEDLLPFDVKGVWESMEECQKL 158 Query: 666 HKIRALGVSNYFI 704 +A+GVSN+ + Sbjct: 159 GLTKAIGVSNFSV 171 >UniRef50_Q4WUF7 Cluster: Aldo-keto reductase, putative; n=3; Pezizomycotina|Rep: Aldo-keto reductase, putative - Aspergillus fumigatus (Sartorya fumigata) Length = 283 Score = 64.9 bits (151), Expect = 5e-09 Identities = 45/149 (30%), Positives = 75/149 (50%), Gaps = 1/149 (0%) Frame = +3 Query: 255 NNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPKY 434 N+ V++P +G ++ V ++ AL+AGYR DTA YGNE + A +K Sbjct: 15 NSDVKIPRLGFGVYRSPTGQCVQSSLR-ALEAGYRHIDTAQFYGNEKEVGEALRKC---- 69 Query: 435 KLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLD-YIDLYLVHNPGIYKLDFENRN 611 + R D+F+ +K+L A ++ + G D Y+DL+L+H+ + + Sbjct: 70 GIPRSDVFVTTKILSPAGSPEATYQKLLESVEKIGGRDGYVDLFLIHS---------SSS 120 Query: 612 SSRIRKQTWATLVDLYHDHKIRALGVSNY 698 S RK+ W L L + K R++GVSN+ Sbjct: 121 GSAGRKELWQALERLLEEGKTRSIGVSNF 149 >UniRef50_Q5UX52 Cluster: Oxidoreductase aldo/keto reductase family; n=1; Haloarcula marismortui|Rep: Oxidoreductase aldo/keto reductase family - Haloarcula marismortui (Halobacterium marismortui) Length = 274 Score = 64.9 bits (151), Expect = 5e-09 Identities = 46/146 (31%), Positives = 73/146 (50%) Frame = +3 Query: 261 GVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPKYKL 440 G +PA+GL T+++ + +TV+ AL GYR DTA YGNE + + + Sbjct: 8 GTSVPALGLGTWQLTG-QSCRETVETALGMGYRHIDTAQAYGNERQVGLG----MDAAAV 62 Query: 441 KRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLDFENRNSSR 620 R D+F+ +KL N +V R+ +L+ LG DY+DL L+H P N Sbjct: 63 DREDVFLTTKLDGSNRDERSV-RRSTRESLNKLGTDYLDLLLIHWP--------NTPWMA 113 Query: 621 IRKQTWATLVDLYHDHKIRALGVSNY 698 +T + D+ + +R +GVSN+ Sbjct: 114 SLSETLGAMNDVVEEGLVRHIGVSNF 139 >UniRef50_A7CUW0 Cluster: 2,5-didehydrogluconate reductase; n=6; Bacteria|Rep: 2,5-didehydrogluconate reductase - Opitutaceae bacterium TAV2 Length = 334 Score = 64.5 bits (150), Expect = 7e-09 Identities = 48/149 (32%), Positives = 75/149 (50%) Frame = +3 Query: 252 LNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPK 431 L++G +P +GL ++M + + A AGYR DTA +YGNE + A + Sbjct: 64 LSDGTSIPQLGLGVWQMPDDGAGVP-IQAAFNAGYRAIDTAPIYGNEEGVGRAIRAS--- 119 Query: 432 YKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLDFENRN 611 L R +++I +K+ G + T RA +L L L+Y+DLYL+H P + K+D Sbjct: 120 -GLPRKELYITTKVWNSAQGYDS-TLRAVRESLGRLQLEYVDLYLIHWP-VPKID----- 171 Query: 612 SSRIRKQTWATLVDLYHDHKIRALGVSNY 698 TW L + D R++GVSN+ Sbjct: 172 ---RYVDTWKALAKIKADGLARSIGVSNF 197 >UniRef50_A5ZYE6 Cluster: Putative uncharacterized protein; n=1; Ruminococcus obeum ATCC 29174|Rep: Putative uncharacterized protein - Ruminococcus obeum ATCC 29174 Length = 263 Score = 64.5 bits (150), Expect = 7e-09 Identities = 39/103 (37%), Positives = 55/103 (53%) Frame = +3 Query: 270 MPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPKYKLKRG 449 MP +GL +K + A++ GYR+ DTA+ Y NE ++ + K + R Sbjct: 1 MPLLGLGLYKTTDAVEAEDAIAAAVQNGYRLLDTASAYKNEEFVGCG----IAKCGVPRK 56 Query: 450 DIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNP 578 D+FI +K+ G V E AF +L LGLDYIDLYL+H P Sbjct: 57 DLFITTKIWNNAQRLGDV-EGAFQRSLDRLGLDYIDLYLIHWP 98 >UniRef50_A7RUA2 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 246 Score = 64.5 bits (150), Expect = 7e-09 Identities = 48/143 (33%), Positives = 70/143 (48%) Frame = +3 Query: 270 MPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPKYKLKRG 449 +P +G T +G L V AL+ GYR+ DTA Y K + + R Sbjct: 1 VPVMGFGTATLGE--DTLSVVKTALETGYRLIDTAQGYPLS---EPQVAKAIADSGIPRK 55 Query: 450 DIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLDFENRNSSRIRK 629 DIFII+KL P Y G T ++ +L L DYIDL+L+H+ + K Sbjct: 56 DIFIITKLHP-RYLGYEPTLKSVEMSLRALSTDYIDLFLIHS------------KTGTWK 102 Query: 630 QTWATLVDLYHDHKIRALGVSNY 698 ++W + +L+ KIR+LGVSN+ Sbjct: 103 ESWKAMEELHRQGKIRSLGVSNF 125 >UniRef50_A2G4I3 Cluster: Oxidoreductase, aldo/keto reductase family protein; n=2; Eukaryota|Rep: Oxidoreductase, aldo/keto reductase family protein - Trichomonas vaginalis G3 Length = 286 Score = 64.5 bits (150), Expect = 7e-09 Identities = 51/153 (33%), Positives = 78/153 (50%), Gaps = 4/153 (2%) Frame = +3 Query: 252 LNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKA----GYRMFDTAALYGNEVYLNFAFKK 419 L+NG ++P IGL + G+ L+T A+K G + DTA LYG+ + F K Sbjct: 10 LSNGNKIPKIGLGCWNFGNPGCPLETEQSAVKTAVNGGMVLLDTAELYGDGLSEEF-LKD 68 Query: 420 LLPKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLDF 599 L+ + K +FI+SK+LP N G + +L +LG++Y+DLYL+H G L Sbjct: 69 LIKPIREK---LFIVSKVLPSNAGRKNIFNSC-EKSLQHLGIEYLDLYLLHWRGRVPL-- 122 Query: 600 ENRNSSRIRKQTWATLVDLYHDHKIRALGVSNY 698 K+T + +L KI+ GVSN+ Sbjct: 123 ---------KETVECMEELVKQGKIKQWGVSNF 146 >UniRef50_Q9HGY0 Cluster: Glycerol dehydrogenase; n=8; Saccharomycetaceae|Rep: Glycerol dehydrogenase - Zygosaccharomyces rouxii (Candida mogii) Length = 310 Score = 64.5 bits (150), Expect = 7e-09 Identities = 52/167 (31%), Positives = 80/167 (47%), Gaps = 16/167 (9%) Frame = +3 Query: 252 LNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPK 431 LN G +P +GL T++ + V +ALKAGYR D AA+YGNE + K + Sbjct: 13 LNTGQTIPQVGLGTWRSKE-NEGYKAVIEALKAGYRHIDGAAVYGNEGEVG----KAIQD 67 Query: 432 YKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNP----------- 578 + R +IF+ +KL C + + A +L LGLDY+ LYLVH P Sbjct: 68 SGVPRNEIFLTTKLW-CTHQRN--PQEALDQSLQRLGLDYVGLYLVHWPVPLRTENIKDG 124 Query: 579 GIYKLDFENRNSSRIRKQ-----TWATLVDLYHDHKIRALGVSNYFI 704 +++ + S + + TW + L K +A+GVSN+ + Sbjct: 125 NLFQFAEKPDGSKDVDLEWNFIKTWELMQKLLESGKTKAIGVSNFSV 171 >UniRef50_Q6CGE9 Cluster: Similar to sp|P47137 Saccharomyces cerevisiae Probable oxidoreductase YJR096W; n=2; Yarrowia lipolytica|Rep: Similar to sp|P47137 Saccharomyces cerevisiae Probable oxidoreductase YJR096W - Yarrowia lipolytica (Candida lipolytica) Length = 287 Score = 64.5 bits (150), Expect = 7e-09 Identities = 47/150 (31%), Positives = 69/150 (46%), Gaps = 4/150 (2%) Frame = +3 Query: 261 GVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPKY-K 437 G +P IGL + + ++V +AL GYR+FDTA Y NE + L Sbjct: 15 GTVIPVIGLGVYSSN---STTKSVTEALNLGYRLFDTANEYQNETDTAKGISEWLKSNPN 71 Query: 438 LKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNL---GLDYIDLYLVHNPGIYKLDFENR 608 +KR D++ +K+ GG T+ L+ GLDYID+ ++H P + Sbjct: 72 VKREDVWYCTKIDDAR-GGYEGTKSRVEEALTKAKVGGLDYIDMLIIHAP------YTAP 124 Query: 609 NSSRIRKQTWATLVDLYHDHKIRALGVSNY 698 + R + W L + D KIR L VSNY Sbjct: 125 PHTETRMKVWKALSEFVDDGKIRTLAVSNY 154 >UniRef50_Q4DJ59 Cluster: Aldo/keto reductase, putative; n=2; Trypanosoma|Rep: Aldo/keto reductase, putative - Trypanosoma cruzi Length = 322 Score = 64.1 bits (149), Expect = 9e-09 Identities = 41/149 (27%), Positives = 76/149 (51%), Gaps = 1/149 (0%) Frame = +3 Query: 255 NNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPKY 434 + G+ +P +G+ T+++ + + + AL+ G+R+ DTAA Y NE ++ A ++ Sbjct: 21 SGGMRIPHMGVGTYELYGDESRIAVLA-ALRLGFRLVDTAAGYHNEEHVGAAIEES---- 75 Query: 435 KLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLDFENRNS 614 ++R ++F++ K+ P + E+ ++ L + Y D L+H PG L E Sbjct: 76 GVQREELFVVVKIAPKAMASEELVEKGIRESVRKLRIAYADCVLIHWPGCGGLKPEEAEG 135 Query: 615 SR-IRKQTWATLVDLYHDHKIRALGVSNY 698 R R + W + L + IR LGVSN+ Sbjct: 136 HRAARHRCWKVMQALKKEGIIRHLGVSNF 164 >UniRef50_Q76L37 Cluster: Conjugated polyketone reductase C1; n=3; Saccharomycetales|Rep: Conjugated polyketone reductase C1 - Candida parapsilosis (Yeast) Length = 304 Score = 64.1 bits (149), Expect = 9e-09 Identities = 52/168 (30%), Positives = 82/168 (48%), Gaps = 13/168 (7%) Frame = +3 Query: 240 QQFTLNNGVEMPAIGLDT----FKMGHF---YTVLQTVDDALKAGYRMFDTAALYGNEVY 398 ++F L+NG ++PA+ T FK GH ++ T++ AL++G+R D A +YG Sbjct: 6 KEFKLSNGNKIPAVAFGTGTKYFKRGHNDLDKQLIGTLELALRSGFRHIDGAEIYGTNKE 65 Query: 399 LNFAFKKLLPKYKLKRGDIFIISKLLPCN--YGGGAVTERAFHNTLS----NLGLDYIDL 560 + A K + L R D+FI K N Y G + +N L +LGL+Y+DL Sbjct: 66 IGIALKNV----GLNRKDVFITDKYNSGNHTYDGKHSKHQNPYNALKADLEDLGLEYVDL 121 Query: 561 YLVHNPGIYKLDFENRNSSRIRKQTWATLVDLYHDHKIRALGVSNYFI 704 YL+H P I ++ + W L ++ R +GVSN+ I Sbjct: 122 YLIHFPYI-----SEKSHGFDLVEAWRYLERAKNEGLARNIGVSNFTI 164 >UniRef50_Q7G764 Cluster: Probable NAD(P)H-dependent oxidoreductase 1; n=32; Eukaryota|Rep: Probable NAD(P)H-dependent oxidoreductase 1 - Oryza sativa subsp. japonica (Rice) Length = 321 Score = 64.1 bits (149), Expect = 9e-09 Identities = 49/153 (32%), Positives = 72/153 (47%), Gaps = 10/153 (6%) Frame = +3 Query: 270 MPAIGLDT--FKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPKYKL- 440 MP +G+ T F + A++ GYR FDTA +Y E + A + + + + Sbjct: 16 MPRVGMGTAAFPFTSSEDTTAAMLRAIELGYRHFDTARIYATEGCVGEAVAEAVRRGLIA 75 Query: 441 KRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVH-----NPGIYKLDF-- 599 R D+F+ SK+ + G V A TL NLG+DY+DL LVH PG Y F Sbjct: 76 SRADVFVTSKIWCSDLHAGRVVPAA-RETLRNLGMDYVDLLLVHWPVSLTPGNYDFPFPK 134 Query: 600 ENRNSSRIRKQTWATLVDLYHDHKIRALGVSNY 698 E S + W + + + RA+GVSN+ Sbjct: 135 EVILPSFDMEGVWRGMEECHRLGLARAIGVSNF 167 >UniRef50_P14065 Cluster: Protein GCY; n=13; Saccharomycetales|Rep: Protein GCY - Saccharomyces cerevisiae (Baker's yeast) Length = 312 Score = 64.1 bits (149), Expect = 9e-09 Identities = 57/169 (33%), Positives = 81/169 (47%), Gaps = 17/169 (10%) Frame = +3 Query: 249 TLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLP 428 +LN G ++P IGL T++ + V ALK GYR DTAA+Y NE + A K Sbjct: 13 SLNTGAQIPQIGLGTWQSKE-NDAYKAVLTALKDGYRHIDTAAIYRNEDQVGQAIKDS-- 69 Query: 429 KYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPG------IYK 590 + R +IF+ +KL + V A +L LGLDY+DLYL+H P I Sbjct: 70 --GVPREEIFVTTKLWCTQHHEPEV---ALDQSLKRLGLDYVDLYLMHWPARLDPAYIKN 124 Query: 591 LDF----ENRNSSRIRK-------QTWATLVDLYHDHKIRALGVSNYFI 704 D ++ SR +TW + +L K +A+GVSN+ I Sbjct: 125 EDILSVPTKKDGSRAVDITNWNFIKTWELMQELPKTGKTKAVGVSNFSI 173 >UniRef50_Q6U5V3 Cluster: Putative uncharacterized protein; n=1; Klebsiella pneumoniae|Rep: Putative uncharacterized protein - Klebsiella pneumoniae Length = 279 Score = 63.7 bits (148), Expect = 1e-08 Identities = 49/149 (32%), Positives = 79/149 (53%) Frame = +3 Query: 252 LNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPK 431 LN+G MP G + + + V + ALKAG+R FDTA Y NE + A + Sbjct: 8 LNDGYYMPRPGCGLWLIDN-RDVDSLIRQALKAGFRHFDTAQAYFNEDGVGRALRYT--- 63 Query: 432 YKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLDFENRN 611 ++ R +FI SK+ + G A T +F+ TL LG++Y++L+L+H P + +N Sbjct: 64 -EVPREQLFITSKIRGRDM-GYARTLVSFNETLERLGVEYLELFLIHWP----IPAKN-- 115 Query: 612 SSRIRKQTWATLVDLYHDHKIRALGVSNY 698 + +TW ++L IR++GVSN+ Sbjct: 116 ---LYVETWEASIELEASGLIRSIGVSNF 141 >UniRef50_A7BA05 Cluster: Putative uncharacterized protein; n=1; Actinomyces odontolyticus ATCC 17982|Rep: Putative uncharacterized protein - Actinomyces odontolyticus ATCC 17982 Length = 292 Score = 63.7 bits (148), Expect = 1e-08 Identities = 50/153 (32%), Positives = 71/153 (46%), Gaps = 2/153 (1%) Frame = +3 Query: 246 FTLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLL 425 F L G +P +G T+K+ T V AL+ GYR DTA +YGNE + A L Sbjct: 19 FMLPTGSPIPVLGFGTYKVAPEDTY-DAVSRALEVGYRHIDTAQMYGNEAEVGAA----L 73 Query: 426 PKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVH--NPGIYKLDF 599 + R D+FI +K+ N+ + +L +L DY+DL LVH P +Y D Sbjct: 74 EASGIAREDLFITTKVDNSNHEPDRAA-ASIRRSLEDLRTDYVDLLLVHWPLPTLYGGDV 132 Query: 600 ENRNSSRIRKQTWATLVDLYHDHKIRALGVSNY 698 W L D ++ RA+G+SNY Sbjct: 133 ---------ALPWPALEDAFNAGGARAIGLSNY 156 >UniRef50_Q4FY75 Cluster: Aldo-keto reductase-like protein; n=5; Trypanosomatidae|Rep: Aldo-keto reductase-like protein - Leishmania major strain Friedlin Length = 372 Score = 63.7 bits (148), Expect = 1e-08 Identities = 39/115 (33%), Positives = 57/115 (49%) Frame = +3 Query: 234 LPQQFTLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAF 413 + + + + +P +G T+++ V AL GYR D A YGNE + A Sbjct: 18 ITHRIAMRDSHTIPQLGFGTYRLP-VSEATDAVAFALSCGYRHVDCAKAYGNEAAVGEAL 76 Query: 414 KKLLPKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNP 578 + L +R D+F+ SKL P + V E A TL+ L LDY+DLYL+H P Sbjct: 77 AQALRTRCTRREDLFVTSKLWPTDQHPDHV-EAACRATLAALQLDYLDLYLIHWP 130 >UniRef50_Q2U219 Cluster: Aldo/keto reductase family proteins; n=6; Pezizomycotina|Rep: Aldo/keto reductase family proteins - Aspergillus oryzae Length = 294 Score = 63.7 bits (148), Expect = 1e-08 Identities = 48/157 (30%), Positives = 77/157 (49%), Gaps = 8/157 (5%) Frame = +3 Query: 252 LNNGVEMPAIGLDT----FKMGHFYTV----LQTVDDALKAGYRMFDTAALYGNEVYLNF 407 LN+ V +P +G T +K +V ++ + A++ GYR D A +YG E L Sbjct: 14 LNDNVSIPILGYGTGTAWYKQAGDDSVNRELVEAIKTAIRLGYRHLDGAEVYGTEAELGV 73 Query: 408 AFKKLLPKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIY 587 A K+ + R ++F+ +K++ A A +L L L+Y+DLYL+H+P Sbjct: 74 AIKES----GIPREELFVTTKVIT----NIADIPSAIDQSLRKLQLNYVDLYLIHSPFFA 125 Query: 588 KLDFENRNSSRIRKQTWATLVDLYHDHKIRALGVSNY 698 K D E +Q WA + + K +A+GVSNY Sbjct: 126 KSDGE-------LQQAWAAMEKVQQAGKAKAIGVSNY 155 >UniRef50_O14088 Cluster: Xylose and arabinose reductase; n=1; Schizosaccharomyces pombe|Rep: Xylose and arabinose reductase - Schizosaccharomyces pombe (Fission yeast) Length = 275 Score = 63.7 bits (148), Expect = 1e-08 Identities = 47/149 (31%), Positives = 72/149 (48%) Frame = +3 Query: 252 LNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPK 431 LNNG++ P ++ + +V AL+ GYR D+A +Y NE A K + + Sbjct: 8 LNNGLKCPQFAYGSYMVNRT-KCFDSVYAALQCGYRHIDSAQMYHNEADCGRAILKFMEE 66 Query: 432 YKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLDFENRN 611 KR DI+ SKL + G T + ++ GL YIDL+L+H+P Sbjct: 67 TGTKREDIWFTSKL--NDLSGYKSTLSSIDASVKACGLGYIDLFLLHSP----------Y 114 Query: 612 SSRIRKQTWATLVDLYHDHKIRALGVSNY 698 RI ++W L + K+RA+GVSN+ Sbjct: 115 GDRI--ESWKALEKGVEEGKLRAIGVSNF 141 >UniRef50_Q9X265 Cluster: Oxidoreductase, aldo/keto reductase family; n=2; Thermotoga|Rep: Oxidoreductase, aldo/keto reductase family - Thermotoga maritima Length = 274 Score = 63.3 bits (147), Expect = 2e-08 Identities = 48/154 (31%), Positives = 76/154 (49%), Gaps = 8/154 (5%) Frame = +3 Query: 261 GVEMPAIGLDTFKMGHFYT--------VLQTVDDALKAGYRMFDTAALYGNEVYLNFAFK 416 G E+PA+GL T+ +G F T +++ + A+K GY DTA YG + Sbjct: 10 GEEIPALGLGTWGIGGFETPDYSRDEEMVELLKTAIKMGYTHIDTAEYYGGG-HTEELIG 68 Query: 417 KLLPKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLD 596 K + ++ R D+FI+SK+ P + + R+ NTL L DY+DLYL+H P Sbjct: 69 KAIKDFR--REDLFIVSKVWPTHLRRDDLL-RSLENTLKRLDTDYVDLYLIHWP------ 119 Query: 597 FENRNSSRIRKQTWATLVDLYHDHKIRALGVSNY 698 N ++T + + + IR +GVSN+ Sbjct: 120 ----NPEIPLEETLSAMAEGVRQGLIRYIGVSNF 149 >UniRef50_Q6RZX1 Cluster: Gld1; n=22; Pezizomycotina|Rep: Gld1 - Trichoderma atroviride (Hypocrea atroviridis) Length = 327 Score = 63.3 bits (147), Expect = 2e-08 Identities = 53/170 (31%), Positives = 80/170 (47%), Gaps = 15/170 (8%) Frame = +3 Query: 246 FTLNNGVEMPAIGLDTF-KMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKL 422 +TLN G ++PA+G TF G V AL GYR D A Y NE + A + Sbjct: 15 YTLNTGAKIPAVGFGTFANEGAKGETYAAVTKALDVGYRHLDCAWFYLNEDEVGDAIRDF 74 Query: 423 LPKYK-LKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLDF 599 L + + R D+FI +K+ + V A N+ NL +DYIDL+LVH P + + Sbjct: 75 LARRPDVTRKDLFICTKVWNHLHEPEDVKWSA-KNSCENLKVDYIDLFLVHWPIAAEKNA 133 Query: 600 E-------------NRNSSRIRKQTWATLVDLYHDHKIRALGVSNYFIWG 710 + N+ + + TW + +L ++A+GVSN+ I G Sbjct: 134 DRTVKIGPDGKYVINKALTENPEPTWRAMEELVDSGIVKAIGVSNWTIPG 183 >UniRef50_A3VHZ9 Cluster: Oxidoreductase; n=1; Rhodobacterales bacterium HTCC2654|Rep: Oxidoreductase - Rhodobacterales bacterium HTCC2654 Length = 278 Score = 62.9 bits (146), Expect = 2e-08 Identities = 40/110 (36%), Positives = 58/110 (52%) Frame = +3 Query: 249 TLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLP 428 TL NGVEMP +GL T+ M + V A++ GYR+ DTA Y NE + + Sbjct: 11 TLANGVEMPQLGLGTWPMTDDEAA-KAVATAIETGYRLIDTAENYKNETGVGQGIRDA-- 67 Query: 429 KYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNP 578 + R ++F+ +K+ + RA +L LGLDYIDL+L+H P Sbjct: 68 --GVARDEVFLTTKMNK-QWHSVDGARRACEASLERLGLDYIDLFLIHWP 114 >UniRef50_Q00XM4 Cluster: Aldo/keto reductase family proteins; n=2; Ostreococcus|Rep: Aldo/keto reductase family proteins - Ostreococcus tauri Length = 336 Score = 62.9 bits (146), Expect = 2e-08 Identities = 45/146 (30%), Positives = 67/146 (45%) Frame = +3 Query: 261 GVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPKYKL 440 G+ MP + T+++ T V DAL+ G++ DTA++YGNE + A + + Sbjct: 59 GITMPMLAFGTYRL-RGETCRDAVRDALRCGFQHVDTASVYGNERDVGEALRACHREVSE 117 Query: 441 KRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLDFENRNSSR 620 + IF+ SK+ P A LG DL LVH PG K ++ Sbjct: 118 R---IFVTSKIAPSEMRSEEEAAAAIAGVNERLGRTP-DLVLVHWPGRDKESPDSERHRD 173 Query: 621 IRKQTWATLVDLYHDHKIRALGVSNY 698 R+ TW L + + RA+GVSNY Sbjct: 174 ARRWTWRALENALKMGQCRAIGVSNY 199 >UniRef50_Q8ZI40 Cluster: 2,5-diketo-D-gluconic acid reductase A; n=74; Bacteria|Rep: 2,5-diketo-D-gluconic acid reductase A - Yersinia pestis Length = 277 Score = 62.9 bits (146), Expect = 2e-08 Identities = 50/151 (33%), Positives = 73/151 (48%) Frame = +3 Query: 252 LNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPK 431 L +G MP +GL ++ T L V AL+ GYR DTAA+Y NE + A K Sbjct: 9 LYDGRLMPQLGLGVWQASIQETEL-AVSKALEVGYRSIDTAAIYKNEEGVGKALKAAA-- 65 Query: 432 YKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLDFENRN 611 + R ++FI +KL + ++A +L L LDY+DLYL+H P + + Sbjct: 66 --VARDELFITTKLWNDDQHN---PQQALETSLQKLQLDYVDLYLIHWP-------DPKQ 113 Query: 612 SSRIRKQTWATLVDLYHDHKIRALGVSNYFI 704 + W LV L IR++GV N+ I Sbjct: 114 DHYV--SAWRELVTLKEQGLIRSIGVCNFHI 142 >UniRef50_UPI000155CAC7 Cluster: PREDICTED: hypothetical protein; n=1; Ornithorhynchus anatinus|Rep: PREDICTED: hypothetical protein - Ornithorhynchus anatinus Length = 419 Score = 62.5 bits (145), Expect = 3e-08 Identities = 43/137 (31%), Positives = 71/137 (51%), Gaps = 1/137 (0%) Frame = +3 Query: 252 LNNGVEMPAIGLDTFKMGHFYTVLQTVDDALK-AGYRMFDTAALYGNEVYLNFAFKKLLP 428 L NG+ +P +GL T +G + V ALK G R DTA YG E+ L K + Sbjct: 17 LANGLNIPILGLGTSHVGGYSH--DAVIYALKECGIRHIDTAKRYGCELLLG----KAIQ 70 Query: 429 KYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLDFENR 608 + +KR +++I +KL +YG + + + + LG++Y+DL+L+H P + Sbjct: 71 ESGVKREELWITTKLWLTDYGYESAKQSCLESC-NRLGVEYLDLFLIHWP---DAQLPGK 126 Query: 609 NSSRIRKQTWATLVDLY 659 +S R +TW + +LY Sbjct: 127 SSREARAETWRAMEELY 143 >UniRef50_Q4Q973 Cluster: Aldo/keto reductase, putative; n=3; Leishmania|Rep: Aldo/keto reductase, putative - Leishmania major Length = 414 Score = 62.5 bits (145), Expect = 3e-08 Identities = 42/144 (29%), Positives = 70/144 (48%), Gaps = 1/144 (0%) Frame = +3 Query: 270 MPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPKYKLKRG 449 +P IG+ T+++ V V AL+ GYR+ DTAA Y NE + + + R Sbjct: 20 VPPIGIGTYELRGDACV-SAVRAALQMGYRLIDTAAAYRNEELVGEG----ISSSGVPRA 74 Query: 450 DIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLDFENRNSSR-IR 626 D+FI+ K+ + + +++ L +DY D L+H PG L ++ + R R Sbjct: 75 DLFIVVKIAMKSMSSDEAVRQGILDSIRKLRIDYADCVLMHWPGCGGLKPQDASGHRAAR 134 Query: 627 KQTWATLVDLYHDHKIRALGVSNY 698 + W + +L K+R GVSN+ Sbjct: 135 ARCWRIMHELQALGKVRYCGVSNF 158 >UniRef50_A2EHN6 Cluster: Oxidoreductase, aldo/keto reductase family protein; n=10; Trichomonas vaginalis|Rep: Oxidoreductase, aldo/keto reductase family protein - Trichomonas vaginalis G3 Length = 312 Score = 62.5 bits (145), Expect = 3e-08 Identities = 35/110 (31%), Positives = 57/110 (51%), Gaps = 1/110 (0%) Frame = +3 Query: 264 VEMPAIGLDTFKMGHFYTVLQTVDDALK-AGYRMFDTAALYGNEVYLNFAFKKLLPKYKL 440 +E+P +G T+ + + A++ G R DTA Y N+ + K++ K K+ Sbjct: 1 MEIPQLGFGTYLANDPAKLKAALHYAIEECGVRHIDTAFAYYNQNVIGETLKEIFAKGKI 60 Query: 441 KRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYK 590 KR D+FI +KL C + + E H L+ L L Y+DL+L+H P +K Sbjct: 61 KREDMFITTKLW-CTHHRKDLVEPELHENLAQLQLSYVDLFLIHQPIAFK 109 >UniRef50_Q4PAT5 Cluster: Putative uncharacterized protein; n=1; Ustilago maydis|Rep: Putative uncharacterized protein - Ustilago maydis (Smut fungus) Length = 700 Score = 62.5 bits (145), Expect = 3e-08 Identities = 52/168 (30%), Positives = 78/168 (46%), Gaps = 15/168 (8%) Frame = +3 Query: 246 FTLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLL 425 FTL NG ++P +G T+KM V A+K GYR D A Y NE + KK Sbjct: 12 FTLANGAQIPKLGFGTWKMSKEQAT-PAVAHAIKTGYRHIDCAWAYRNEDAVAAGIKKA- 69 Query: 426 PKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLD--- 596 + R +++ SKL + V E+A +L +LG DY+DLYL+H P + Sbjct: 70 ---GVPRSQLWLTSKLWNSFHHPEHV-EKALDASLKDLGTDYLDLYLMHWPVAFLNSKGS 125 Query: 597 ------------FENRNSSRIRKQTWATLVDLYHDHKIRALGVSNYFI 704 E+ + SR T+ + ++ K+R +GVSN+ I Sbjct: 126 MVPSIRSTGGHPVESEDLSRDFMATYRVMEEMVKKGKVRNIGVSNFNI 173 >UniRef50_Q8EVS8 Cluster: Oxidoreductase; n=1; Mycoplasma penetrans|Rep: Oxidoreductase - Mycoplasma penetrans Length = 289 Score = 62.1 bits (144), Expect = 4e-08 Identities = 50/154 (32%), Positives = 75/154 (48%), Gaps = 3/154 (1%) Frame = +3 Query: 249 TLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLP 428 TLNNG ++P+IG F++ T V A+ GYR+ DTA Y NE K Sbjct: 10 TLNNGNKIPSIGFGVFQIPKEETA-DCVKKAISIGYRLIDTAQAYHNEKETGLGIK---- 64 Query: 429 KYKLKRGDIFIISKLLPCNYGGGAVTERAFHN---TLSNLGLDYIDLYLVHNPGIYKLDF 599 +KR +IF+ +K+ NY ER + + +L L Y+DL L+H P F Sbjct: 65 LSGVKREEIFLTTKVWVSNY------ERCYESVIESLKRLDTSYLDLILLHQP------F 112 Query: 600 ENRNSSRIRKQTWATLVDLYHDHKIRALGVSNYF 701 N + + L LY ++K+R +GVSN++ Sbjct: 113 GN------YYKAYQDLERLYKENKVRNIGVSNFW 140 >UniRef50_A5PDA8 Cluster: Putative oxidoreductase protein; n=1; Erythrobacter sp. SD-21|Rep: Putative oxidoreductase protein - Erythrobacter sp. SD-21 Length = 272 Score = 62.1 bits (144), Expect = 4e-08 Identities = 48/149 (32%), Positives = 75/149 (50%) Frame = +3 Query: 252 LNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPK 431 LN+G ++P +G T++M Q V A+ GY + DTAA+YGNE K + K Sbjct: 9 LNDGRQIPQLGFGTWQMEE-EDAPQAVSTAIDVGYWLIDTAAIYGNE--------KGVGK 59 Query: 432 YKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLDFENRN 611 + DIF+ +K+ + G T RA L LG +++D+ L+H P K F + Sbjct: 60 GVGEWSDIFLQTKIWNDSQGYDR-TLRAAEKCLERLGREHVDMLLIHWPCPEKDQFVD-- 116 Query: 612 SSRIRKQTWATLVDLYHDHKIRALGVSNY 698 TW L++L K +++GVSN+ Sbjct: 117 -------TWKALIELRDAGKAKSIGVSNF 138 >UniRef50_A7D6Q0 Cluster: Aldo/keto reductase; n=1; Halorubrum lacusprofundi ATCC 49239|Rep: Aldo/keto reductase - Halorubrum lacusprofundi ATCC 49239 Length = 309 Score = 62.1 bits (144), Expect = 4e-08 Identities = 49/155 (31%), Positives = 80/155 (51%) Frame = +3 Query: 234 LPQQFTLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAF 413 +P Q TL +G +PA+GL T+ + + +V AL +GY DTA Y NE A Sbjct: 34 IPTQ-TLPSGDTLPALGLGTYALDDDQ-IADSVRAALSSGYTHIDTAEGYHNEE----AI 87 Query: 414 KKLLPKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKL 593 ++L +Y R D+F+ SK+L N G ++ + +L L DY+DLYL+H P Sbjct: 88 GEVLAEYD--RDDVFLTSKVLAKNLGYESLIQSC-EASLERLETDYLDLYLIHWP----- 139 Query: 594 DFENRNSSRIRKQTWATLVDLYHDHKIRALGVSNY 698 N + +++ + +L+ +R +GVSN+ Sbjct: 140 -----NPAISLRESLQAMAELHDRGLVRNVGVSNF 169 >UniRef50_Q8VC28 Cluster: Aldo-keto reductase family 1 member C13; n=11; Theria|Rep: Aldo-keto reductase family 1 member C13 - Mus musculus (Mouse) Length = 323 Score = 62.1 bits (144), Expect = 4e-08 Identities = 50/160 (31%), Positives = 74/160 (46%), Gaps = 11/160 (6%) Frame = +3 Query: 252 LNNGVEMPAIGLDTFKMGHF--YTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLL 425 LN+G +PA+G T+K L+ AL GYR DTA Y E + A + + Sbjct: 10 LNDGHLIPALGFGTYKPKEVPKSKSLEAACLALDVGYRHVDTAYAYQVEEEIGQAIQSKI 69 Query: 426 PKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKL---D 596 +KR D+FI +KL C + + A +L L LDY+DLY++H P K D Sbjct: 70 KAGVVKREDLFITTKLW-CTCFRPELVKPALEKSLKKLQLDYVDLYIMHYPVPMKSGDND 128 Query: 597 FE-NRNSSRIRK-----QTWATLVDLYHDHKIRALGVSNY 698 F N + TW L + ++++GVSN+ Sbjct: 129 FPVNEQGKSLLDTVDFCDTWERLEECKDAGLVKSIGVSNF 168 >UniRef50_UPI0000E45E29 Cluster: PREDICTED: similar to aldose reductase; n=1; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to aldose reductase - Strongylocentrotus purpuratus Length = 274 Score = 61.7 bits (143), Expect = 5e-08 Identities = 37/87 (42%), Positives = 47/87 (54%) Frame = +3 Query: 330 VDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPKYKLKRGDIFIISKLLPCNYGGGAVTE 509 V A+ GYR D A +YGNE + K+ +KR DIFI SKL + V E Sbjct: 16 VKAAIDCGYRHIDCAHVYGNEAEVGAGLKEKFDANVVKREDIFITSKLWNNKHHPDDV-E 74 Query: 510 RAFHNTLSNLGLDYIDLYLVHNPGIYK 590 +A TL NL L Y+DLYL+H P Y+ Sbjct: 75 QACDITLKNLQLSYVDLYLMHWPMAYQ 101 >UniRef50_Q5K8C5 Cluster: Aldo-keto reductase, putative; n=1; Filobasidiella neoformans|Rep: Aldo-keto reductase, putative - Cryptococcus neoformans (Filobasidiella neoformans) Length = 303 Score = 61.7 bits (143), Expect = 5e-08 Identities = 47/155 (30%), Positives = 69/155 (44%) Frame = +3 Query: 234 LPQQFTLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAF 413 L + +++G +P GL ++M T V AL+AGYR DTA Y NE A Sbjct: 29 LDARLKMHDGNAIPQFGLGVYEMNDKETY-DCVKWALEAGYRHVDTAEWYENEAPCGKAI 87 Query: 414 KKLLPKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKL 593 L R +IF+ SKL + A + +L G++Y DLYL+H+ Sbjct: 88 ADFLKATGTSREEIFLTSKLKNNSSYEQAFVD--LKGSLKRSGVEYFDLYLMHSA----- 140 Query: 594 DFENRNSSRIRKQTWATLVDLYHDHKIRALGVSNY 698 IRK W L D ++++GVSN+ Sbjct: 141 ----IGGPVIRKNVWKALCDAQSQGLVKSIGVSNF 171 >UniRef50_Q9A2X8 Cluster: Oxidoreductase, aldo/keto reductase family; n=3; Caulobacter|Rep: Oxidoreductase, aldo/keto reductase family - Caulobacter crescentus (Caulobacter vibrioides) Length = 279 Score = 61.3 bits (142), Expect = 7e-08 Identities = 37/105 (35%), Positives = 61/105 (58%) Frame = +3 Query: 264 VEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPKYKLK 443 V MPA+G T+++ + T + V+ AL+ GYR DTA +YGNE + A + +K Sbjct: 13 VLMPALGFGTWQLENG-TAVPLVEKALEIGYRHIDTAQIYGNERDVGAAIR----NSGVK 67 Query: 444 RGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNP 578 R +IF+ +K+ + G + +R+ +L LG+D +DL L+H P Sbjct: 68 RDEIFLTTKVWIDQFADGDL-QRSAEKSLEKLGVDQVDLLLLHWP 111 >UniRef50_Q7WSY4 Cluster: Putative aldo-keto reductase; n=1; Propionibacterium freudenreichii subsp. shermanii|Rep: Putative aldo-keto reductase - Propionibacterium freudenreichii subsp. shermanii Length = 280 Score = 61.3 bits (142), Expect = 7e-08 Identities = 38/109 (34%), Positives = 58/109 (53%) Frame = +3 Query: 252 LNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPK 431 L+ G MP +G+ T+ + V A++ GYR+ DTA YGNE + A ++ P Sbjct: 13 LSGGTRMPMLGMGTWPLKG-EECRAAVASAIEQGYRLVDTAEAYGNEEAVGKAVREAGPD 71 Query: 432 YKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNP 578 R +IF+ +K + V E A ++L LGLDY+DL+L+H P Sbjct: 72 ----RAEIFVTTKFSKQWHSRKGVHE-ALEHSLERLGLDYVDLFLMHWP 115 >UniRef50_Q9ZUJ6 Cluster: T2K10.1 protein; n=16; core eudicotyledons|Rep: T2K10.1 protein - Arabidopsis thaliana (Mouse-ear cress) Length = 176 Score = 61.3 bits (142), Expect = 7e-08 Identities = 40/132 (30%), Positives = 67/132 (50%), Gaps = 7/132 (5%) Frame = +3 Query: 324 QTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPKYKLK-RGDIFIISKLLPCNYGGGA 500 +TV +A+K GYR FDT+ Y E + A + + ++ R + F+ +KL + GG Sbjct: 41 ETVIEAIKLGYRHFDTSPRYQTEEPIGEALAEAVSLGLVRSRSEFFVTTKLWCADAHGGL 100 Query: 501 VTERAFHNTLSNLGLDYIDLYLVH-----NPGIYKLDFENRNSSRIR-KQTWATLVDLYH 662 V A +L NL LDY+DLY++H PG YK + + + + W+ + + Sbjct: 101 VVP-AIKRSLKNLKLDYLDLYIIHWPVSSKPGKYKFPIDEDDFMPMDFEVVWSEMEECQR 159 Query: 663 DHKIRALGVSNY 698 + +GVSN+ Sbjct: 160 LGLAKCIGVSNF 171 >UniRef50_Q7R2T6 Cluster: GLP_291_56367_57278; n=1; Giardia lamblia ATCC 50803|Rep: GLP_291_56367_57278 - Giardia lamblia ATCC 50803 Length = 303 Score = 61.3 bits (142), Expect = 7e-08 Identities = 33/87 (37%), Positives = 50/87 (57%), Gaps = 2/87 (2%) Frame = +3 Query: 324 QTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLL--PKYKLKRGDIFIISKLLPCNYGGG 497 + + A+K GYR FD A YGNE + FK++ Y +KR D++I+SKL P N+ Sbjct: 19 EAIRSAVKLGYRHFDCAYRYGNERMIGEVFKEIFNDDSYGVKREDLWIVSKLWP-NFHEP 77 Query: 498 AVTERAFHNTLSNLGLDYIDLYLVHNP 578 TL +L L+Y+D++L+H P Sbjct: 78 EKVAYQISETLRDLQLEYLDVFLMHWP 104 >UniRef50_Q5BKE9 Cluster: LOC594893 protein; n=5; Xenopus tropicalis|Rep: LOC594893 protein - Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) Length = 345 Score = 60.9 bits (141), Expect = 9e-08 Identities = 44/129 (34%), Positives = 64/129 (49%), Gaps = 9/129 (6%) Frame = +3 Query: 339 ALKAGYRMFDTAALYGNEVYLNFAFKKLLPKYKLKRGDIFIISKLLPCNYGGGAVTERAF 518 AL GYR D A LY +E + AF++ LKR D+F SKL + + A Sbjct: 63 ALDLGYRHVDGAFLYSSETGVGQAFREKFADGTLKREDLFYTSKLWN-TFHQPHLVRPAL 121 Query: 519 HNTLSNLGLDYIDLYLVHNPGIYK----LDFENRNSSRI-----RKQTWATLVDLYHDHK 671 TLS L +DY+DLYL+H P +K L +N + + QTW L + Sbjct: 122 EKTLSFLQMDYVDLYLIHMPMSFKPAEELFPKNEDGTCAFDQPDLLQTWQALEECRDAGL 181 Query: 672 IRALGVSNY 698 ++++GVSN+ Sbjct: 182 VKSIGVSNF 190 >UniRef50_Q5KD52 Cluster: Oxidoreductase, putative; n=1; Filobasidiella neoformans|Rep: Oxidoreductase, putative - Cryptococcus neoformans (Filobasidiella neoformans) Length = 321 Score = 60.9 bits (141), Expect = 9e-08 Identities = 49/153 (32%), Positives = 76/153 (49%), Gaps = 3/153 (1%) Frame = +3 Query: 243 QFTLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAA---LYGNEVYLNFAF 413 + TLN+G +PAI T+K+ T Q V A+ G+ DTA +Y NE + A Sbjct: 5 EITLNDGHRIPAIAFGTWKIPKEVTPFQ-VGQAIDVGFDHIDTAQGRIVYHNEEEVGQAI 63 Query: 414 KKLLPKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKL 593 K+ L R +++ +K + G GA ++ +L LGL+Y+DLYL+H+P + K Sbjct: 64 KES----GLSRNQLWVTTKWSGID-GKGA--RQSIGESLEKLGLEYLDLYLIHSPQVTKG 116 Query: 594 DFENRNSSRIRKQTWATLVDLYHDHKIRALGVS 692 D K W L L + K +++GVS Sbjct: 117 DI---------KGAWKELETLQKEGKTKSIGVS 140 >UniRef50_A3T261 Cluster: Putative uncharacterized protein; n=1; Sulfitobacter sp. NAS-14.1|Rep: Putative uncharacterized protein - Sulfitobacter sp. NAS-14.1 Length = 274 Score = 60.1 bits (139), Expect = 2e-07 Identities = 47/150 (31%), Positives = 72/150 (48%) Frame = +3 Query: 249 TLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLP 428 TL + P++G TF++ TV V AL G+R DTA Y NE + ++ Sbjct: 4 TLIGPAQTPSLGFGTFQLEQD-TVADMVAAALSEGFRHIDTAQAYQNEEQVGEGLRRA-- 60 Query: 429 KYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLDFENR 608 ++R ++F+ +K+LP ++ A T A +L LG DY+DL L+H P Sbjct: 61 --DVRRDEVFLTTKILPEHFSPEAFTAAA-DASLKRLGTDYVDLLLLHWP---------- 107 Query: 609 NSSRIRKQTWATLVDLYHDHKIRALGVSNY 698 + +T L DL K+R GVSN+ Sbjct: 108 SKEVPIAETIGALNDLISAGKVRHGGVSNF 137 >UniRef50_A1CAM7 Cluster: Aldo-keto reductase, putative; n=9; Dikarya|Rep: Aldo-keto reductase, putative - Aspergillus clavatus Length = 283 Score = 60.1 bits (139), Expect = 2e-07 Identities = 44/150 (29%), Positives = 74/150 (49%), Gaps = 2/150 (1%) Frame = +3 Query: 255 NNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPKY 434 N+ V +P +G ++ V Q+ AL+AGYR DTA Y NE + A L Sbjct: 15 NSSVRIPRLGFGVYRSPTRQCV-QSCLTALQAGYRNIDTAQFYANEQEVGEA----LRTS 69 Query: 435 KLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLD--YIDLYLVHNPGIYKLDFENR 608 + R D+F+ +K+L G T + ++ +G + Y+DL+L+H+ + Sbjct: 70 GIPRSDVFVTTKIL-SPAGSPEATYKKLLESVEKIGGENGYVDLFLIHS---------SS 119 Query: 609 NSSRIRKQTWATLVDLYHDHKIRALGVSNY 698 + S RK+ W L L + K +++GVSN+ Sbjct: 120 SGSAGRKELWQALEKLLEEGKTKSIGVSNF 149 >UniRef50_Q11B35 Cluster: Aldo/keto reductase; n=1; Mesorhizobium sp. BNC1|Rep: Aldo/keto reductase - Mesorhizobium sp. (strain BNC1) Length = 253 Score = 59.7 bits (138), Expect = 2e-07 Identities = 49/148 (33%), Positives = 73/148 (49%), Gaps = 3/148 (2%) Frame = +3 Query: 270 MPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPKYKLKRG 449 MP +GL T+++ H +TV A GYRM DT+ YG + + A + L R Sbjct: 1 MPILGLGTWQLTH--ETARTVRAAFDLGYRMVDTSGDYGTQSAIGEAIRAS----GLDRD 54 Query: 450 DIFIISKLLPCNYGGGAVTERAFHNTLSNL---GLDYIDLYLVHNPGIYKLDFENRNSSR 620 DI++++K+ TE A++ T +NL GLDY DL L+H P R+ + Sbjct: 55 DIYLVTKV--------EETEDAYNATQANLRELGLDYADLILIHRP--------PRHGA- 97 Query: 621 IRKQTWATLVDLYHDHKIRALGVSNYFI 704 ++ W L+ D R +GVSNY I Sbjct: 98 -GEELWRALIRAREDGLTRDIGVSNYSI 124 >UniRef50_A5AD50 Cluster: Putative uncharacterized protein; n=3; Magnoliophyta|Rep: Putative uncharacterized protein - Vitis vinifera (Grape) Length = 304 Score = 59.7 bits (138), Expect = 2e-07 Identities = 33/76 (43%), Positives = 44/76 (57%) Frame = +3 Query: 246 FTLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLL 425 F LN G +MP++GL T++ V Q V A+K GYR D A +YGNE + KKL Sbjct: 8 FQLNTGAKMPSVGLGTWQSDPGL-VGQAVAIAIKVGYRHIDCAQVYGNEEEIGIVLKKLF 66 Query: 426 PKYKLKRGDIFIISKL 473 +KR D++I SKL Sbjct: 67 DDGVVKREDLWITSKL 82 >UniRef50_A3C1Z7 Cluster: Putative uncharacterized protein; n=2; Oryza sativa (japonica cultivar-group)|Rep: Putative uncharacterized protein - Oryza sativa subsp. japonica (Rice) Length = 288 Score = 59.7 bits (138), Expect = 2e-07 Identities = 50/162 (30%), Positives = 79/162 (48%), Gaps = 13/162 (8%) Frame = +3 Query: 252 LNNGVEMPAIGLDT--FKMGHF--YTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKK 419 L++G MP +G+ T F +G TV V A++AGYR FDTAA+Y E L A + Sbjct: 6 LSSGKPMPRVGMGTASFPLGATDPSTVKDVVLRAIEAGYRHFDTAAVYQTEAILGDAVAE 65 Query: 420 LL-PKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKL- 593 + R +++I SKL + G V + L + ++Y+DLYL+H P +L Sbjct: 66 AVRAGLVASRDELYITSKLWVAHAHPGHVLP-SLRRALRKMQMEYLDLYLIHFPVSMRLA 124 Query: 594 -DFENRNSSR------IRKQTWATLVDLYHDHKIRALGVSNY 698 D E+ S+ + W + + +A+GVSN+ Sbjct: 125 EDPESMTYSKDDLVMMDMEGVWKEMEECQRLGLTKAIGVSNF 166 >UniRef50_UPI0000D9A956 Cluster: PREDICTED: similar to aldo-keto reductase family 1, member B10, partial; n=1; Macaca mulatta|Rep: PREDICTED: similar to aldo-keto reductase family 1, member B10, partial - Macaca mulatta Length = 275 Score = 59.3 bits (137), Expect = 3e-07 Identities = 34/96 (35%), Positives = 54/96 (56%), Gaps = 5/96 (5%) Frame = +3 Query: 318 VLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPKYKLKRGDIFIISKL-----LPC 482 V + V A+ AGYR D A +Y NE + A ++ + + +KR D+FI+SK+ L Sbjct: 48 VKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEKIQEQAVKREDLFIVSKVHMAHWLWT 107 Query: 483 NYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYK 590 + + +AF TL +L L Y+D+YL+H P +K Sbjct: 108 TFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFK 143 >UniRef50_Q6F7K7 Cluster: 2,5-diketo-D-gluconate reductase; n=20; Bacteria|Rep: 2,5-diketo-D-gluconate reductase - Acinetobacter sp. (strain ADP1) Length = 297 Score = 59.3 bits (137), Expect = 3e-07 Identities = 47/149 (31%), Positives = 70/149 (46%) Frame = +3 Query: 252 LNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPK 431 L++G +PA+G T+ + V T+ AL GYRM D+A Y NE + A ++ Sbjct: 27 LHDGHSIPALGFGTYTLKGQQGV-DTMLRALGHGYRMLDSAFNYENEGAVGAAVRQS--- 82 Query: 432 YKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLDFENRN 611 L R +IFI SKL P + +L + DY+DLYL+H P Sbjct: 83 -GLLRDEIFITSKL-PGRHHAYDKAMETIEESLYRMQFDYLDLYLIHWP---------NP 131 Query: 612 SSRIRKQTWATLVDLYHDHKIRALGVSNY 698 + + W L+D IR++GVSN+ Sbjct: 132 QQGLYIEAWQALIDAQKKGYIRSIGVSNF 160 >UniRef50_Q9U2J5 Cluster: Putative uncharacterized protein; n=2; Caenorhabditis|Rep: Putative uncharacterized protein - Caenorhabditis elegans Length = 339 Score = 58.8 bits (136), Expect = 3e-07 Identities = 46/166 (27%), Positives = 79/166 (47%), Gaps = 14/166 (8%) Frame = +3 Query: 249 TLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLP 428 TLN+G EMP IG T+++ + V DAL+AGYR D+A + N+ + K Sbjct: 8 TLNSGYEMPVIGYGTWQLPKNLAA-ERVRDALEAGYRHIDSALSFKNQEEVAAGIKDWCK 66 Query: 429 KYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNP---------- 578 K++R ++F+ SK+ + ++ L Y+DL ++H P Sbjct: 67 IRKVRREELFLSSKIWNTYHSRNRCMQQ-IDEMLEIFETTYMDLIVIHWPFGWAEDEPPG 125 Query: 579 --GIYK--LDFENRNSSRIRKQTWATLVDLYHDHKIRALGVSNYFI 704 G++ + + R S +TW L D + KIR++G++N+ I Sbjct: 126 ERGLWPRGANGKMRYSDVDYLETWKALEDAHRSGKIRSIGLANFNI 171 >UniRef50_A6RMS0 Cluster: Putative uncharacterized protein; n=1; Botryotinia fuckeliana B05.10|Rep: Putative uncharacterized protein - Botryotinia fuckeliana B05.10 Length = 286 Score = 58.8 bits (136), Expect = 3e-07 Identities = 54/155 (34%), Positives = 74/155 (47%), Gaps = 2/155 (1%) Frame = +3 Query: 246 FTLNNGVEMPAIGLDTFKMGHFYT-VLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKL 422 F L NG +PAIGL TF+ V V A++AGYR D AA YGNE + A K Sbjct: 8 FRLVNGSTLPAIGLGTFQGDDGNEKVKNIVKAAIQAGYRHIDGAAAYGNEEAIGDAIK-- 65 Query: 423 LPKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYI-DLYLVHNPGIYKLDF 599 + + R + L + ERA +L LGL+Y+ YL PG +D+ Sbjct: 66 --ESGISRDE-------LAQPWHEPKDVERALDLSLEALGLEYVPHAYL---PGPNNVDY 113 Query: 600 ENRNSSRIRKQTWATLVDLYHDHKIRALGVSNYFI 704 E SR +TW + L K +A+G+SN+ I Sbjct: 114 ER---SRKYTETWQAMEKLVDSGKAKAIGLSNFNI 145 >UniRef50_Q5UYI9 Cluster: Oxidoreductase; n=1; Haloarcula marismortui|Rep: Oxidoreductase - Haloarcula marismortui (Halobacterium marismortui) Length = 264 Score = 58.8 bits (136), Expect = 3e-07 Identities = 47/128 (36%), Positives = 64/128 (50%) Frame = +3 Query: 315 TVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPKYKLKRGDIFIISKLLPCNYGG 494 TV ++V L GY DTA Y NE + A L Y R D+F+ SK+LP + Sbjct: 13 TVQKSVRAGLNVGYAHVDTAEGYKNESEIGEA----LADYD--REDVFLTSKVLPKHLDY 66 Query: 495 GAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLDFENRNSSRIRKQTWATLVDLYHDHKI 674 +V E A +L LG DY+DLYLVH P N + ++T + L+ KI Sbjct: 67 ESVIE-ACEASLDRLGTDYLDLYLVHWP----------NPATSIRETMNAMATLHDQGKI 115 Query: 675 RALGVSNY 698 R +GVSN+ Sbjct: 116 RNVGVSNF 123 >UniRef50_P51857 Cluster: 3-oxo-5-beta-steroid 4-dehydrogenase (EC 1.3.1.3) (Delta(4)-3- ketosteroid 5-beta-reductase); n=124; cellular organisms|Rep: 3-oxo-5-beta-steroid 4-dehydrogenase (EC 1.3.1.3) (Delta(4)-3- ketosteroid 5-beta-reductase) - Homo sapiens (Human) Length = 326 Score = 58.8 bits (136), Expect = 3e-07 Identities = 48/161 (29%), Positives = 75/161 (46%), Gaps = 12/161 (7%) Frame = +3 Query: 252 LNNGVEMPAIGLDTF---KMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKL 422 L++G +P IGL T+ K +V A+ GYR D A +Y NE + A ++ Sbjct: 12 LSDGNSIPIIGLGTYSEPKSTPKGACATSVKVAIDTGYRHIDGAYIYQNEHEVGEAIREK 71 Query: 423 LPKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLDFE 602 + + K++R DIF KL N+ V TL L LDY+DLY++ P +K E Sbjct: 72 IAEGKVRREDIFYCGKLWATNHVPEMV-RPTLERTLRVLQLDYVDLYIIEVPMAFKPGDE 130 Query: 603 ----NRNSSRIRKQ-----TWATLVDLYHDHKIRALGVSNY 698 + N + + TW + +++LGVSN+ Sbjct: 131 IYPRDENGKWLYHKSNLCATWEAMEACKDAGLVKSLGVSNF 171 >UniRef50_Q8ET73 Cluster: 2,5-diketo-D-gluconate reductase; n=12; Bacteria|Rep: 2,5-diketo-D-gluconate reductase - Oceanobacillus iheyensis Length = 280 Score = 58.4 bits (135), Expect = 5e-07 Identities = 44/150 (29%), Positives = 70/150 (46%) Frame = +3 Query: 249 TLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLP 428 TL++G+ +P +G T+++ V Q +++A+ GYR+ DTA Y NE + A + Sbjct: 9 TLHDGLTIPKVGFGTYRLNGNDGV-QAINNAIDHGYRLIDTAYNYENEGTVGEAVR---- 63 Query: 429 KYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLDFENR 608 + R + I SK LP Y +L LDY DLYL+H P + Sbjct: 64 RSSTPREQLLITSK-LPGRYHHYDKAVTTIQESLYRANLDYYDLYLIHWPNPIQ------ 116 Query: 609 NSSRIRKQTWATLVDLYHDHKIRALGVSNY 698 I + W L++ IR++GV N+ Sbjct: 117 ---DIYVEAWQALIEAKRRGYIRSIGVCNF 143 >UniRef50_Q0GU15 Cluster: ORF28; n=3; Bacteria|Rep: ORF28 - Lactococcus lactis Length = 281 Score = 58.4 bits (135), Expect = 5e-07 Identities = 45/147 (30%), Positives = 69/147 (46%), Gaps = 4/147 (2%) Frame = +3 Query: 270 MPAIGLDTFKMGHFYTV----LQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPKYK 437 +PAIGL T+ MG+ ++ + + AG + DTA +YGN + + + Sbjct: 11 VPAIGLGTWHMGNSTATRAKEIKAIQAGIDAGATVIDTAEMYGNGRSESLVGEAIA---N 67 Query: 438 LKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLDFENRNSS 617 + R +F+I K+LP N ++ + +L LG DY+DLYL H G L Sbjct: 68 IDREKLFLIDKVLPSNASADRMSH-SLDTSLKLLGTDYVDLYLYHWRGAVPL-------- 118 Query: 618 RIRKQTWATLVDLYHDHKIRALGVSNY 698 +T TL L KI+ GVSN+ Sbjct: 119 ---SETVETLQSLQQQGKIKHWGVSNF 142 >UniRef50_Q8K023 Cluster: Aldo-keto reductase family 1 member C18; n=72; Tetrapoda|Rep: Aldo-keto reductase family 1 member C18 - Mus musculus (Mouse) Length = 323 Score = 58.4 bits (135), Expect = 5e-07 Identities = 36/115 (31%), Positives = 56/115 (48%), Gaps = 2/115 (1%) Frame = +3 Query: 240 QQFTLNNGVEMPAIGLDTFKMGHFYTV--LQTVDDALKAGYRMFDTAALYGNEVYLNFAF 413 Q+ LN+G +P +G T+ +++ A+ G+ D + LY NE + A Sbjct: 6 QKIELNDGHSIPVLGFGTYATEEHLKKKSMESTKIAIDVGFCHIDCSHLYQNEEEIGQAI 65 Query: 414 KKLLPKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNP 578 + +KR DIF SKL ++ V + N+L L LDY+DLYL+H P Sbjct: 66 LSKIEDGTVKREDIFYTSKLWSTSHRPELVRP-SLENSLRKLNLDYVDLYLIHFP 119 >UniRef50_A3UJS6 Cluster: Oxidoreductase; n=3; Alphaproteobacteria|Rep: Oxidoreductase - Oceanicaulis alexandrii HTCC2633 Length = 275 Score = 58.0 bits (134), Expect = 6e-07 Identities = 36/110 (32%), Positives = 58/110 (52%) Frame = +3 Query: 249 TLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLP 428 T NG ++P +G T+++ + V ALK GYR DTA +YGNE + +K Sbjct: 5 TQANGADIPKLGFGTWQLED-EDAARGVATALKTGYRHIDTAQIYGNEAAVGDGWK---- 59 Query: 429 KYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNP 578 + +KR D F+ +K+ + G + + + +L L DY+DL L+H P Sbjct: 60 QSGVKREDFFLTTKVWRDKFRDGDL-QASVKESLDKLKTDYVDLLLLHWP 108 >UniRef50_Q01J82 Cluster: OSIGBa0152K17.5 protein; n=28; Magnoliophyta|Rep: OSIGBa0152K17.5 protein - Oryza sativa (Rice) Length = 323 Score = 58.0 bits (134), Expect = 6e-07 Identities = 46/155 (29%), Positives = 72/155 (46%), Gaps = 9/155 (5%) Frame = +3 Query: 261 GVEMPAIGLDTFKMGHFY--TVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPK- 431 G MPA+G+ T T AL+ G+R FDTAALYG E L A + + Sbjct: 14 GRPMPAVGVGTADSAATSPETKRGAALAALEVGFRHFDTAALYGTEAPLGEAIAEATRRG 73 Query: 432 YKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVH-----NPGIYKLD 596 R ++F+ +KL C + + +L NL ++Y+DLYLVH PG L Sbjct: 74 LVASREEVFVTTKLW-CTQCHPGLVLPSLRESLRNLQMEYVDLYLVHWPISVKPGPPMLP 132 Query: 597 FENRNSSRIR-KQTWATLVDLYHDHKIRALGVSNY 698 + ++ + W + + + +A+GVSN+ Sbjct: 133 VKREDAVPFDFEGVWRAMEECHRLGLAKAIGVSNF 167 >UniRef50_P91021 Cluster: Putative uncharacterized protein; n=1; Caenorhabditis elegans|Rep: Putative uncharacterized protein - Caenorhabditis elegans Length = 134 Score = 58.0 bits (134), Expect = 6e-07 Identities = 29/75 (38%), Positives = 48/75 (64%) Frame = +3 Query: 249 TLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLP 428 TL+N MPA+GL T++ + V+ V A+K GY + DTA+ Y NE ++ A K+++ Sbjct: 49 TLSNAHSMPAVGLGTWQ-SNAEDVISAVKAAVKNGYSLIDTASGYNNEEFIGTAIKEVIA 107 Query: 429 KYKLKRGDIFIISKL 473 + +KR D+FI +K+ Sbjct: 108 EGVVKREDLFITTKV 122 >UniRef50_Q4V008 Cluster: Oxidoreductase; n=4; Proteobacteria|Rep: Oxidoreductase - Xanthomonas campestris pv. campestris (strain 8004) Length = 267 Score = 57.6 bits (133), Expect = 8e-07 Identities = 44/145 (30%), Positives = 71/145 (48%) Frame = +3 Query: 270 MPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPKYKLKRG 449 +PA GL TF++ V+ +V +AL GYR DTA +Y NE + A + + R Sbjct: 3 VPAFGLGTFRLKD-QVVIDSVRNALALGYRAIDTAQIYDNEAQVGQA----IADAGVPRD 57 Query: 450 DIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLDFENRNSSRIRK 629 +F+ +K+ + + + + +L LG DY+DL L+H P ++ +R+ Sbjct: 58 QLFVTTKIWVDRFSRDTL-QPSLQESLRKLGTDYVDLTLIHWP-------SPKDQVPMRE 109 Query: 630 QTWATLVDLYHDHKIRALGVSNYFI 704 A L D RA+GVSN+ I Sbjct: 110 YLEA-LADAKAQGLTRAIGVSNFTI 133 >UniRef50_Q4Q5X1 Cluster: Aldehyde reductase, putative; n=75; cellular organisms|Rep: Aldehyde reductase, putative - Leishmania major Length = 286 Score = 57.6 bits (133), Expect = 8e-07 Identities = 47/153 (30%), Positives = 71/153 (46%), Gaps = 4/153 (2%) Frame = +3 Query: 252 LNNGVEMPAIGLDTFKMGHF----YTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKK 419 L +G PA+G + MG L + ++AG + DTA +YGN + Sbjct: 9 LPDGTAAPALGQGVWMMGETPENRTRELAALRAGMEAGMTLIDTAEMYGNGRSERLVAEA 68 Query: 420 LLPKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLDF 599 + + R +FI+SK+LP N A+ R+ +L N+G DY+DLYL+H G L Sbjct: 69 IK---ETPRERLFIVSKVLPTNASRAAIF-RSCDASLQNIGTDYLDLYLLHWRGRVPL-- 122 Query: 600 ENRNSSRIRKQTWATLVDLYHDHKIRALGVSNY 698 +T + +L KIR GVSN+ Sbjct: 123 ---------SETVTCMEELVKSGKIRRWGVSNF 146 >UniRef50_UPI0000499B0E Cluster: oxidoreductase, aldo/keto reductase family; n=1; Entamoeba histolytica HM-1:IMSS|Rep: oxidoreductase, aldo/keto reductase family - Entamoeba histolytica HM-1:IMSS Length = 307 Score = 57.2 bits (132), Expect = 1e-06 Identities = 49/164 (29%), Positives = 77/164 (46%), Gaps = 6/164 (3%) Frame = +3 Query: 231 ILPQQFTLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYL-NF 407 +L F LNNG MPAIGL T+ + V + V AL+ GYR+ D A Y NE + Sbjct: 1 MLQHGFFLNNGKFMPAIGLGTW-LAAPGEVGKAVTLALENGYRLIDCARFYKNEKEIGEM 59 Query: 408 AFKKLLPKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIY 587 + L + R ++F+ SKL + E ++ +L Y+DLYL+H P Sbjct: 60 GIEPFLKNH--PREELFVTSKLWMDQV--TRIRESCL-ESIQDLKCKYLDLYLIHWPIAL 114 Query: 588 KLDFENRNS-----SRIRKQTWATLVDLYHDHKIRALGVSNYFI 704 K+D N + W + L + ++++G+SN+ I Sbjct: 115 KVDASNPPKPEDFLDMDITEIWQEMERLVDEGLVKSIGLSNFTI 158 >UniRef50_A6WDZ5 Cluster: Aldo/keto reductase; n=5; Bacteria|Rep: Aldo/keto reductase - Kineococcus radiotolerans SRS30216 Length = 343 Score = 57.2 bits (132), Expect = 1e-06 Identities = 37/111 (33%), Positives = 57/111 (51%), Gaps = 2/111 (1%) Frame = +3 Query: 252 LNNGVEMPAIGLDTFKMGHFYT--VLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLL 425 L G +PAIG+ TF + V V A+ AGYR+ D AA+YGNE + A + Sbjct: 18 LRGGATVPAIGIGTFGSDRYSPAEVAAAVAGAVAAGYRLVDCAAVYGNEAQVGEALAGAV 77 Query: 426 PKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNP 578 + R ++F++SK+ + A + H +L +L LD++D VH P Sbjct: 78 AG-GVDRDELFVVSKVWN-DAHAPADAVASVHRSLRDLRLDHLDAVFVHWP 126 >UniRef50_UPI00015B4912 Cluster: PREDICTED: similar to aldo-keto reductase; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to aldo-keto reductase - Nasonia vitripennis Length = 353 Score = 56.8 bits (131), Expect = 1e-06 Identities = 40/112 (35%), Positives = 56/112 (50%), Gaps = 1/112 (0%) Frame = +3 Query: 246 FTLNNGVEMPAIGLDTFKMGHFYTVLQTV-DDALKAGYRMFDTAALYGNEVYLNFAFKKL 422 + L++G P +GL T + VL+TV AL+ G DT+ +Y NE + K Sbjct: 31 YRLSSGHNFPIVGLGTHGLNE--DVLETVLTGALEKGIGHIDTSFVYKNEETIGKVLKDW 88 Query: 423 LPKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNP 578 K KR DIF+ SKL P E+ +L LGL Y+D+YL+H P Sbjct: 89 FAKGG-KREDIFVTSKL-PYYDNHPESVEKYIKLSLEKLGLQYLDMYLIHAP 138 >UniRef50_Q11DV1 Cluster: Aldo/keto reductase; n=10; Alphaproteobacteria|Rep: Aldo/keto reductase - Mesorhizobium sp. (strain BNC1) Length = 274 Score = 56.8 bits (131), Expect = 1e-06 Identities = 35/107 (32%), Positives = 56/107 (52%) Frame = +3 Query: 258 NGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPKYK 437 +G +PA+G F+M V + + AL+AG+R FDTA +Y NE A + L + Sbjct: 7 HGATIPALGFGVFRMSDA-EVERIIPAALEAGFRHFDTAQIYQNEA----ALGRALERAG 61 Query: 438 LKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNP 578 +R D+F+ +K+ NY + +L L +D +DL L+H P Sbjct: 62 ARREDLFLTTKVWVDNYSADKFA-ASVDESLEKLKVDQVDLLLLHWP 107 >UniRef50_Q0SFM4 Cluster: Probable 2,5-didehydrogluconate reductase; n=1; Rhodococcus sp. RHA1|Rep: Probable 2,5-didehydrogluconate reductase - Rhodococcus sp. (strain RHA1) Length = 265 Score = 56.8 bits (131), Expect = 1e-06 Identities = 34/105 (32%), Positives = 59/105 (56%) Frame = +3 Query: 264 VEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPKYKLK 443 +++P +GL T+ + + V ++AGYR+ DTA +Y NE + A L + + Sbjct: 2 MDIPPLGLGTWPLTG-PDATRAVLSGIEAGYRLIDTATIYDNEDAVGVA----LAECGVP 56 Query: 444 RGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNP 578 R ++F+ +KL ++ G + A +L NLGLD +DL+L+H P Sbjct: 57 REELFVTTKLRGSDHVSGDI-RGAVERSLKNLGLDRLDLFLIHWP 100 >UniRef50_A2EYY6 Cluster: Oxidoreductase, aldo/keto reductase family protein; n=9; Trichomonas vaginalis G3|Rep: Oxidoreductase, aldo/keto reductase family protein - Trichomonas vaginalis G3 Length = 308 Score = 56.8 bits (131), Expect = 1e-06 Identities = 38/104 (36%), Positives = 56/104 (53%), Gaps = 1/104 (0%) Frame = +3 Query: 270 MPAIGLDTFKMGHFYTVLQTVDDALK-AGYRMFDTAALYGNEVYLNFAFKKLLPKYKLKR 446 +P IGL T+K ++ + A+K AGY D A Y NE + A ++ +KR Sbjct: 4 IPTIGLGTWKSPRSEDLVNAITYAIKEAGYVHIDCALCYENEDIVGQALQQCWDS-GIKR 62 Query: 447 GDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNP 578 +I+I SKL ++ + E A TL +L LDY+DLYL+H P Sbjct: 63 ENIWITSKLWNTHHRL-EIVEEACRKTLKDLRLDYLDLYLMHYP 105 >UniRef50_A6SJ74 Cluster: Putative uncharacterized protein; n=1; Botryotinia fuckeliana B05.10|Rep: Putative uncharacterized protein - Botryotinia fuckeliana B05.10 Length = 166 Score = 56.8 bits (131), Expect = 1e-06 Identities = 44/113 (38%), Positives = 57/113 (50%), Gaps = 2/113 (1%) Frame = +3 Query: 366 DTAALYGNEVYLNFAFKKLLPKYKLKRGDIFIISKLLP--CNYGGGAVTERAFHNTLSNL 539 D+AA Y NE A +K + R DIF SK+ P +Y T+ TL Sbjct: 5 DSAAAYRNEGPCAIAIQKS----SIPREDIFFTSKIPPRALSYEN---TKAQVAKTLMET 57 Query: 540 GLDYIDLYLVHNPGIYKLDFENRNSSRIRKQTWATLVDLYHDHKIRALGVSNY 698 GLDYIDL L+H P + R++ RK W LV+ + KIR+LGVSNY Sbjct: 58 GLDYIDLMLIHAP------YGGRDA---RKGAWKALVEAQEEGKIRSLGVSNY 101 >UniRef50_Q6CEJ0 Cluster: Yarrowia lipolytica chromosome B of strain CLIB122 of Yarrowia lipolytica; n=1; Yarrowia lipolytica|Rep: Yarrowia lipolytica chromosome B of strain CLIB122 of Yarrowia lipolytica - Yarrowia lipolytica (Candida lipolytica) Length = 302 Score = 56.4 bits (130), Expect = 2e-06 Identities = 47/156 (30%), Positives = 72/156 (46%), Gaps = 7/156 (4%) Frame = +3 Query: 252 LNNGVEMPAIGLDT---FKMG----HFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFA 410 L+NG+E+PAIG + +K ++ V A+ AG+ DTA YG E + A Sbjct: 8 LSNGLEIPAIGFGSGTKWKRPPGEKEERELIDAVVSAINAGHLHIDTAEFYGTEKQIGEA 67 Query: 411 FKKLLPKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYK 590 K + + R DIF+ SK L + + N L L DY DL+L+H P Sbjct: 68 IK----ESGVPRKDIFLTSKTLFGLLADDPI--ESISNQLKTLQTDYFDLFLIHVPPNDD 121 Query: 591 LDFENRNSSRIRKQTWATLVDLYHDHKIRALGVSNY 698 ++++ + W L LY +A+GVSN+ Sbjct: 122 INYD-------LAKAWGVLEQLYEKGLAKAIGVSNH 150 >UniRef50_Q59Z55 Cluster: Potential aldo/keto reductase; n=6; Saccharomycetales|Rep: Potential aldo/keto reductase - Candida albicans (Yeast) Length = 319 Score = 56.4 bits (130), Expect = 2e-06 Identities = 36/114 (31%), Positives = 60/114 (52%), Gaps = 3/114 (2%) Frame = +3 Query: 246 FTLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLL 425 + LNNG +P IG T+ + T ALK GYR DTA Y NE ++ K+ L Sbjct: 16 YKLNNGSHIPVIGFGTYLLDASQAADLTYQ-ALKDGYRHIDTALAYHNEKEVSQGIKRFL 74 Query: 426 PKY-KLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNL--GLDYIDLYLVHNP 578 + +++R DI+ +K + G T++A +++ ++Y+DL L+H+P Sbjct: 75 KDHPEVQRSDIWFTTK-IDTQSLGYEETKKAVERIKNDVKDNIEYVDLILIHSP 127 >UniRef50_Q9HM42 Cluster: Alcohol dehydrogenase related protein; n=1; Thermoplasma acidophilum|Rep: Alcohol dehydrogenase related protein - Thermoplasma acidophilum Length = 284 Score = 56.4 bits (130), Expect = 2e-06 Identities = 43/149 (28%), Positives = 74/149 (49%), Gaps = 1/149 (0%) Frame = +3 Query: 261 GVEMPAIGLDTFKM-GHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPKYK 437 G ++ IG+ T+ + G ++++ AL G DTA +YG E + A K Sbjct: 13 GRKVSVIGVGTWSLEGSRSENVRSIRYALDHGVNFIDTAEMYGTEDIVGEAIKGY----- 67 Query: 438 LKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLDFENRNSS 617 +R D+FI +K+ P ++ V ++ +L LG DY+DLY +H P N S Sbjct: 68 -RREDLFIATKVWPTHFAYHDVL-KSCEESLKKLGTDYVDLYQLHWP----------NPS 115 Query: 618 RIRKQTWATLVDLYHDHKIRALGVSNYFI 704 K+T + + L + +IR +G+SN+ + Sbjct: 116 VSIKETMSAMEKLVDEGRIRYIGISNFSV 144 >UniRef50_Q5NLW3 Cluster: Putative oxidoreductase; n=1; Zymomonas mobilis|Rep: Putative oxidoreductase - Zymomonas mobilis Length = 273 Score = 56.0 bits (129), Expect = 2e-06 Identities = 46/151 (30%), Positives = 70/151 (46%) Frame = +3 Query: 252 LNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPK 431 LN+G MPAIG +++ V GYR DTAA Y NE + + Sbjct: 9 LNDGHSMPAIGQGVYQLNPAQAE-SMVALGYDLGYRAVDTAAWYENEEGVGEGLRS---- 63 Query: 432 YKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLDFENRN 611 + FI +KL+P + G A ++ NLG+ ++LYL+H PG + +E Sbjct: 64 ---RHARSFITTKLMPQDMGRVNCFV-ALDKSIRNLGVTSLNLYLIHWPGQDRKRYE--- 116 Query: 612 SSRIRKQTWATLVDLYHDHKIRALGVSNYFI 704 +TW TL+ + K ++GVSN+ I Sbjct: 117 ------ETWQTLIQIRAIGKASSIGVSNFTI 141 >UniRef50_A7P424 Cluster: Chromosome chr1 scaffold_5, whole genome shotgun sequence; n=1; Vitis vinifera|Rep: Chromosome chr1 scaffold_5, whole genome shotgun sequence - Vitis vinifera (Grape) Length = 247 Score = 56.0 bits (129), Expect = 2e-06 Identities = 50/168 (29%), Positives = 78/168 (46%), Gaps = 13/168 (7%) Frame = +3 Query: 234 LPQQFTLNNGVEMPAIGLDT--FKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNF 407 +P+ + G +P +G+ T + T++ ++ A++ GYR FD A Y +E L Sbjct: 4 IPEMTLGSTGKAIPLVGMVTTVYPFAPSETMIDSILTAIELGYRHFDCVAAYLSEKPLGE 63 Query: 408 AFKKLLPKYKLK-RGDIFIISKLLPCNYGGGAVTERAFHNTLS---------NLGLDYID 557 A KK + +K R ++FI SKL C+ A NTL NL LDY+D Sbjct: 64 AIKKAVKLGLIKSRDELFITSKLW-CSDAHHDRVLPALQNTLKISSILSFSKNLQLDYLD 122 Query: 558 LYLVH-NPGIYKLDFENRNSSRIRKQTWATLVDLYHDHKIRALGVSNY 698 LYL+H + G +D + W + D +A+GVSN+ Sbjct: 123 LYLIHWSDGHLPIDLGS---------VWKAMEDFQKLSLTKAIGVSNF 161 >UniRef50_Q76L36 Cluster: Conjugated polyketone reductase C2; n=1; Candida parapsilosis|Rep: Conjugated polyketone reductase C2 - Candida parapsilosis (Yeast) Length = 307 Score = 56.0 bits (129), Expect = 2e-06 Identities = 48/168 (28%), Positives = 79/168 (47%), Gaps = 13/168 (7%) Frame = +3 Query: 231 ILPQQFTLNNGVEMP-AIGLDT-FKMGHFYTVLQT--VDD---ALKAGYRMFDTAALYGN 389 +LP+ F +G E+ A+G T +K + T VD+ LK G+R DTA Y Sbjct: 6 LLPKTFRTKSGKEISIALGTGTKWKQAQTINDVSTELVDNILLGLKLGFRHIDTAEAYNT 65 Query: 390 EVYLNFAFKKLLPKYKLKRGDIFIISKLLPCNYGGGAVT------ERAFHNTLSNLGLDY 551 + + A K+ + R DI++ +K P G G++ + L+ LG+DY Sbjct: 66 QKEVGEALKRT----DVPREDIWVTTKYSP---GWGSIKAYSKSPSDSIDKALAQLGVDY 118 Query: 552 IDLYLVHNPGIYKLDFENRNSSRIRKQTWATLVDLYHDHKIRALGVSN 695 +DL+L+H+P + +Q W LV+ K+R +G+SN Sbjct: 119 VDLFLIHSP----FFTTEQTHGYTLEQAWEALVEAKKAGKVREIGISN 162 >UniRef50_A7D7K7 Cluster: Aldo/keto reductase; n=1; Halorubrum lacusprofundi ATCC 49239|Rep: Aldo/keto reductase - Halorubrum lacusprofundi ATCC 49239 Length = 265 Score = 56.0 bits (129), Expect = 2e-06 Identities = 41/112 (36%), Positives = 57/112 (50%), Gaps = 1/112 (0%) Frame = +3 Query: 264 VEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPKYKLK 443 +E+P +GL T ++ TV AL+AGYR DTA +Y NE A + + + Sbjct: 4 LELP-LGLGTSRLDDPAECRATVAAALEAGYRHVDTAQMYDNET----AVGEGIATADVD 58 Query: 444 RGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNP-GIYKLD 596 R D+ + +K+ P N V E A +L LGLD +DL VH P G Y D Sbjct: 59 RDDVVVATKIHPDNLAPADVRETA-RKSLDRLGLDRVDLLYVHWPTGAYDPD 109 >UniRef50_Q5T2L2 Cluster: Aldo-keto reductase family 1 member C-like protein 1; n=14; Eutheria|Rep: Aldo-keto reductase family 1 member C-like protein 1 - Homo sapiens (Human) Length = 302 Score = 56.0 bits (129), Expect = 2e-06 Identities = 34/111 (30%), Positives = 53/111 (47%), Gaps = 2/111 (1%) Frame = +3 Query: 252 LNNGVEMPAIGLDTFKMGHF--YTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLL 425 LN+G MP +G T+ H + A+ G+R D+A LY NE + A + + Sbjct: 13 LNDGPFMPVLGFGTYAPDHTPKSQAAEATKVAIDVGFRHIDSAYLYQNEEEVGQAIWEKI 72 Query: 426 PKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNP 578 +KR +IF KL + + A +L LG DY+DL+++H P Sbjct: 73 ADGTVKREEIFYTIKLW-ATFFRAELVHPALERSLKKLGPDYVDLFIIHVP 122 >UniRef50_Q9P734 Cluster: Related to 2, 5-diketo-D-gluconic acid reductase; n=5; Pezizomycotina|Rep: Related to 2, 5-diketo-D-gluconic acid reductase - Neurospora crassa Length = 289 Score = 55.6 bits (128), Expect = 3e-06 Identities = 49/160 (30%), Positives = 72/160 (45%), Gaps = 4/160 (2%) Frame = +3 Query: 231 ILPQQFTLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFA 410 +L ++ L+NG+ +P I L + M T + V AL AGYR FD+A Y NE A Sbjct: 8 MLSRRVKLSNGLSIPQIQLGLYMMSGPETT-RAVRWALGAGYRGFDSAQWYYNEREAGQA 66 Query: 411 FKKLLPKYK----LKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNP 578 L + L R D+ SKL + AV + ++ GL YIDL+L+H+P Sbjct: 67 ILSFLSSPENTAGLTRKDVHFTSKLRDNSTNYDAV-RASISKSVKASGLGYIDLFLLHSP 125 Query: 579 GIYKLDFENRNSSRIRKQTWATLVDLYHDHKIRALGVSNY 698 R +W + D +++ GVSNY Sbjct: 126 ---------LGGREARLTSWKAVEDAVLAGEVKMAGVSNY 156 >UniRef50_Q5B5R6 Cluster: Putative uncharacterized protein; n=1; Emericella nidulans|Rep: Putative uncharacterized protein - Emericella nidulans (Aspergillus nidulans) Length = 682 Score = 55.6 bits (128), Expect = 3e-06 Identities = 41/110 (37%), Positives = 56/110 (50%) Frame = +3 Query: 240 QQFTLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKK 419 + F LN G +PA+GL T + V + V ALK GYR DTA G E + A K Sbjct: 412 RSFRLNTGALIPAVGLGTRRAQKPGLVYRAVRSALKTGYRHIDTAMSSGVEHEIGQAVK- 470 Query: 420 LLPKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLV 569 + R +++ +KL N V E A +LS LG+DY+DLYL+ Sbjct: 471 ---DSGVSRSQVWVTTKL--DNRWHTRVQE-ALDMSLSELGMDYVDLYLM 514 >UniRef50_UPI000038E317 Cluster: hypothetical protein Faci_03001732; n=1; Ferroplasma acidarmanus fer1|Rep: hypothetical protein Faci_03001732 - Ferroplasma acidarmanus fer1 Length = 278 Score = 55.2 bits (127), Expect = 4e-06 Identities = 39/116 (33%), Positives = 58/116 (50%) Frame = +3 Query: 351 GYRMFDTAALYGNEVYLNFAFKKLLPKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTL 530 G + DTA LY E + A K KR ++F+ SK+ P + ++ E+A + +L Sbjct: 52 GINLIDTAELYRTEKLVGTAIKSY------KRDELFLASKVFPTHLSPKSL-EKALNRSL 104 Query: 531 SNLGLDYIDLYLVHNPGIYKLDFENRNSSRIRKQTWATLVDLYHDHKIRALGVSNY 698 NL DYIDLY +H P N + K+T T+ + KIR +GVSN+ Sbjct: 105 KNLDTDYIDLYQIHFP----------NPTVDIKKTLRTMEKMVDKGKIRHIGVSNF 150 >UniRef50_Q28P63 Cluster: Aldo/keto reductase; n=4; Rhodobacteraceae|Rep: Aldo/keto reductase - Jannaschia sp. (strain CCS1) Length = 276 Score = 55.2 bits (127), Expect = 4e-06 Identities = 39/148 (26%), Positives = 71/148 (47%) Frame = +3 Query: 255 NNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPKY 434 ++G ++P +G +++ +TV A++ GYRM D A LY NE L + Sbjct: 10 HDGAQIPQVGFGIWQVPQDIAG-ETVRSAIEIGYRMIDGAYLYMNEAGLGEGLRAS---- 64 Query: 435 KLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLDFENRNS 614 L R ++F+ +K+ N G A + +L +G++ +DL L+H P S Sbjct: 65 GLPRDEVFVTTKVWN-NEQGAAKARASVERSLKTIGVEQLDLVLIHWP---------VPS 114 Query: 615 SRIRKQTWATLVDLYHDHKIRALGVSNY 698 + +TW D+ + +R++G SN+ Sbjct: 115 QDLYLETWKAFQDMRDEGLMRSIGTSNF 142 Database: uniref50 Posted date: Oct 5, 2007 11:19 AM Number of letters in database: 575,637,011 Number of sequences in database: 1,657,284 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.279 0.0580 0.190 Matrix: BLOSUM62 Gap Penalties: Existence: 9, Extension: 2 Number of Hits to DB: 1,211,982,708 Number of Sequences: 1657284 Number of extensions: 22438353 Number of successful extensions: 52476 Number of sequences better than 10.0: 449 Number of HSP's better than 10.0 without gapping: 43259 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 49670 length of database: 575,637,011 effective HSP length: 104 effective length of database: 403,279,475 effective search space used: 162521628425 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 37 (14.9 bits) X3: 62 (25.0 bits) S1: 41 (21.7 bits)
- SilkBase 1999-2023 -