Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= 030731E7_B08_e634_04.seq
(1525 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
X15414-1|CAA33460.1| 316|Homo sapiens protein ( Human mRNA for ... 92 6e-18
M59783-1|AAA51712.1| 316|Homo sapiens aldose reductase protein. 92 6e-18
M34720-1|AAA35560.1| 316|Homo sapiens protein ( Human aldose re... 92 6e-18
J05474-1|AAA51715.1| 316|Homo sapiens aldose reductase protein. 92 6e-18
J05017-1|AAA51714.1| 316|Homo sapiens ALDR1 protein. 92 6e-18
J04795-1|AAA51713.1| 316|Homo sapiens ALDR1 protein. 92 6e-18
CR542203-1|CAG47000.1| 316|Homo sapiens AKR1B1 protein. 92 6e-18
CR450351-1|CAG29347.1| 316|Homo sapiens AKR1B1 protein. 92 6e-18
BT019859-1|AAV38662.1| 316|Homo sapiens aldo-keto reductase fam... 92 6e-18
BC010391-1|AAH10391.1| 316|Homo sapiens aldo-keto reductase fam... 92 6e-18
BC000260-1|AAH00260.1| 316|Homo sapiens aldo-keto reductase fam... 92 6e-18
AF328729-1|AAN09721.1| 316|Homo sapiens CTCL tumor antigen HD-C... 92 6e-18
AF032455-1|AAB88851.1| 316|Homo sapiens aldose reductase protein. 92 6e-18
AB209796-1|BAD93033.1| 260|Homo sapiens aldo-keto reductase fam... 91 7e-18
BC005387-1|AAH05387.1| 316|Homo sapiens aldo-keto reductase fam... 86 3e-16
U37100-1|AAC17469.1| 316|Homo sapiens aldose reductase-like pep... 80 2e-14
CR541801-1|CAG46600.1| 316|Homo sapiens AKR1B10 protein. 80 2e-14
BT006794-1|AAP35440.1| 316|Homo sapiens aldo-keto reductase fam... 80 2e-14
BC008837-1|AAH08837.1| 316|Homo sapiens aldo-keto reductase fam... 80 2e-14
AF052577-1|AAC36465.1| 316|Homo sapiens aldo-keto reductase pro... 80 2e-14
AF524864-1|AAO13380.1| 316|Homo sapiens aldo-ketoreductase prot... 76 4e-13
J04794-1|AAA51711.1| 325|Homo sapiens ALDR1 protein. 75 5e-13
CR457010-1|CAG33291.1| 325|Homo sapiens AKR1A1 protein. 75 5e-13
BT007003-1|AAP35649.1| 325|Homo sapiens aldo-keto reductase fam... 75 5e-13
BC005394-1|AAH05394.1| 325|Homo sapiens aldo-keto reductase fam... 75 5e-13
BC000670-1|AAH00670.1| 325|Homo sapiens aldo-keto reductase fam... 75 5e-13
AL355480-3|CAI22459.1| 325|Homo sapiens aldo-keto reductase fam... 75 5e-13
AF112485-1|AAF01260.1| 325|Homo sapiens aldehyde reductase prot... 75 5e-13
AF036683-1|AAB92369.1| 325|Homo sapiens aldehyde reductase prot... 75 5e-13
U05861-1|AAA18115.1| 323|Homo sapiens hepatic dihydrodiol dehyd... 74 1e-12
U05684-1|AAA16227.1| 323|Homo sapiens dihydrodiol dehydrogenase... 74 1e-12
M86609-1|AAB02880.1| 323|Homo sapiens dihydrodiol dehydrogenase... 74 1e-12
BT007197-1|AAP35861.1| 323|Homo sapiens aldo-keto reductase fam... 74 1e-12
BC040210-1|AAH40210.1| 323|Homo sapiens aldo-keto reductase fam... 74 1e-12
BC020216-1|AAH20216.1| 323|Homo sapiens aldo-keto reductase fam... 74 1e-12
BC015490-1|AAH15490.1| 323|Homo sapiens aldo-keto reductase fam... 74 1e-12
AL713867-2|CAI16409.1| 323|Homo sapiens aldo-keto reductase fam... 74 1e-12
AB032150-1|BAA92886.1| 323|Homo sapiens 20 alph-hydroxysteroid ... 74 1e-12
AB031083-1|BAA92883.1| 323|Homo sapiens 20 alpha-hydroxysteroid... 74 1e-12
S68290-1|AAD14012.1| 320|Homo sapiens chlordecone reductase hom... 73 2e-12
S68287-1|AAD14010.1| 323|Homo sapiens chlordecone reductase pro... 71 1e-11
D26125-1|BAA05122.1| 321|Homo sapiens 3 alpha-hydroxysteroid/di... 71 1e-11
DQ269985-1|ABB76132.1| 323|Homo sapiens type II 3a-hydroxystero... 71 1e-11
BC020744-1|AAH20744.1| 323|Homo sapiens aldo-keto reductase fam... 71 1e-11
AL355303-2|CAI14202.1| 323|Homo sapiens aldo-keto reductase fam... 71 1e-11
AB045829-1|BAA99542.1| 323|Homo sapiens 3alpha-hydroxysteroid d... 71 1e-11
AB032163-1|BAA92893.1| 323|Homo sapiens dihydrodiol dehydrogena... 71 1e-11
AB031085-1|BAA92885.1| 323|Homo sapiens dihydrodiol dehydrogena... 71 1e-11
AL355480-2|CAI22458.1| 147|Homo sapiens aldo-keto reductase fam... 69 5e-11
U05598-1|AAA20937.1| 323|Homo sapiens dihydrodiol dehydrogenase... 69 6e-11
S68330-1|AAD14013.1| 323|Homo sapiens chlordecone reductase hom... 69 6e-11
L32592-1|AAB38486.1| 323|Homo sapiens dihydrodiol dehydrogenase... 69 6e-11
BT006653-1|AAP35299.1| 323|Homo sapiens aldo-keto reductase fam... 69 6e-11
BC063574-1|AAH63574.1| 323|Homo sapiens aldo-keto reductase fam... 69 6e-11
BC007024-1|AAH07024.1| 323|Homo sapiens aldo-keto reductase fam... 69 6e-11
AL713867-1|CAI16408.1| 323|Homo sapiens aldo-keto reductase fam... 69 6e-11
AL391427-1|CAI14726.1| 323|Homo sapiens aldo-keto reductase fam... 69 6e-11
AB209017-1|BAD92254.1| 286|Homo sapiens aldo-keto reductase fam... 69 6e-11
AB032153-1|BAA92891.1| 323|Homo sapiens bile acid-binding prote... 69 6e-11
AB031084-1|BAA92884.1| 323|Homo sapiens bile acid-binding prote... 69 6e-11
AB021654-1|BAA36169.1| 323|Homo sapiens DD2/bile acid-binding p... 69 6e-11
D17793-1|BAA04619.2| 325|Homo sapiens KIAA0119 protein. 68 8e-11
BT007286-1|AAP35950.1| 323|Homo sapiens aldo-keto reductase fam... 68 8e-11
BC019230-1|AAH19230.1| 323|Homo sapiens aldo-keto reductase fam... 68 8e-11
BC001479-1|AAH01479.1| 323|Homo sapiens aldo-keto reductase fam... 68 8e-11
AL391427-4|CAI14729.1| 323|Homo sapiens aldo-keto reductase fam... 68 8e-11
AF149416-1|AAF07272.2| 323|Homo sapiens 3-alpha hydroxysteroid ... 68 8e-11
AB032157-1|BAA92892.1| 323|Homo sapiens prostaglandin F synthas... 68 8e-11
AB018580-1|BAA88488.1| 323|Homo sapiens hluPGFS protein. 68 8e-11
S68288-1|AAD14011.1| 323|Homo sapiens chlordecone reductase hom... 66 2e-10
D26124-1|BAA05121.1| 306|Homo sapiens dihydrodiol dehydrogenase... 66 2e-10
L43839-1|AAB41916.1| 323|Homo sapiens 3-alpha-hydroxysteroid de... 66 4e-10
BC002862-1|AAH02862.1| 307|Homo sapiens AKR1CL2 protein protein. 66 4e-10
AF263242-1|AAK58523.1| 320|Homo sapiens aldo-keto reductase loo... 66 4e-10
AB055603-1|BAC54568.1| 307|Homo sapiens aldo-keto reductase rel... 66 4e-10
AB040822-1|BAC54567.1| 222|Homo sapiens aldo-keto reductase rel... 66 4e-10
AB040821-1|BAC54566.1| 263|Homo sapiens aldo-keto reductase rel... 66 4e-10
AB040820-1|BAC54565.1| 250|Homo sapiens aldo-keto reductase rel... 66 4e-10
M33375-1|AAA35658.1| 308|Homo sapiens protein ( Human chlordeco... 64 1e-09
Z28339-1|CAA82193.1| 326|Homo sapiens delta 4-3-oxosteroid 5 be... 59 5e-08
BC130627-1|AAI30628.1| 326|Homo sapiens aldo-keto reductase fam... 59 5e-08
BC130625-1|AAI30626.1| 326|Homo sapiens aldo-keto reductase fam... 59 5e-08
AF283659-1|AAG39381.1| 326|Homo sapiens 5-beta steroid reductas... 59 5e-08
BC101205-1|AAI01206.1| 129|Homo sapiens aldo-keto reductase fam... 56 3e-07
BC101204-1|AAI01205.1| 129|Homo sapiens aldo-keto reductase fam... 56 3e-07
AL391427-2|CAI14727.1| 302|Homo sapiens aldo-keto reductase fam... 56 3e-07
AL355303-1|CAI14201.1| 302|Homo sapiens aldo-keto reductase fam... 56 3e-07
AK131335-1|BAD18494.1| 129|Homo sapiens protein ( Homo sapiens ... 56 3e-07
AB037902-1|BAA92887.1| 130|Homo sapiens truncated aldo-keto red... 55 8e-07
AL713867-3|CAI16410.1| 247|Homo sapiens aldo-keto reductase fam... 46 5e-04
BC015232-1|AAH15232.2| 148|Homo sapiens transmembrane protein 1... 33 3.6
AK128040-1|BAC87244.1| 245|Homo sapiens protein ( Homo sapiens ... 33 3.6
>X15414-1|CAA33460.1| 316|Homo sapiens protein ( Human mRNA for
aldose reductase (EC 1.1.1.2). ).
Length = 316
Score = 91.9 bits (218), Expect = 6e-18
Identities = 60/165 (36%), Positives = 91/165 (55%), Gaps = 10/165 (6%)
Frame = +3
Query: 234 LPQQFTLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAF 413
+ + LNNG +MP +GL T+K V + V A+ GYR D A +Y NE + A
Sbjct: 1 MASRLLLNNGAKMPILGLGTWKSPPGQ-VTEAVKVAIDVGYRHIDCAHVYQNENEVGVAI 59
Query: 414 KKLLPKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVH-----NP 578
++ L + +KR ++FI+SKL C Y + + A TLS+L LDY+DLYL+H P
Sbjct: 60 QEKLREQVVKREELFIVSKLW-CTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKP 118
Query: 579 G--IYKLDFENRN---SSRIRKQTWATLVDLYHDHKIRALGVSNY 698
G + LD E+ N S TWA + +L + ++A+G+SN+
Sbjct: 119 GKEFFPLD-ESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNF 162
>M59783-1|AAA51712.1| 316|Homo sapiens aldose reductase protein.
Length = 316
Score = 91.9 bits (218), Expect = 6e-18
Identities = 60/165 (36%), Positives = 91/165 (55%), Gaps = 10/165 (6%)
Frame = +3
Query: 234 LPQQFTLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAF 413
+ + LNNG +MP +GL T+K V + V A+ GYR D A +Y NE + A
Sbjct: 1 MASRLLLNNGAKMPILGLGTWKSPPGQ-VTEAVKVAIDVGYRHIDCAHVYQNENEVGVAI 59
Query: 414 KKLLPKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVH-----NP 578
++ L + +KR ++FI+SKL C Y + + A TLS+L LDY+DLYL+H P
Sbjct: 60 QEKLREQVVKREELFIVSKLW-CTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKP 118
Query: 579 G--IYKLDFENRN---SSRIRKQTWATLVDLYHDHKIRALGVSNY 698
G + LD E+ N S TWA + +L + ++A+G+SN+
Sbjct: 119 GKEFFPLD-ESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNF 162
>M34720-1|AAA35560.1| 316|Homo sapiens protein ( Human aldose
reductase mRNA, complete cds. ).
Length = 316
Score = 91.9 bits (218), Expect = 6e-18
Identities = 60/165 (36%), Positives = 91/165 (55%), Gaps = 10/165 (6%)
Frame = +3
Query: 234 LPQQFTLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAF 413
+ + LNNG +MP +GL T+K V + V A+ GYR D A +Y NE + A
Sbjct: 1 MASRLLLNNGAKMPILGLGTWKSPPGQ-VTEAVKVAIDVGYRHIDCAHVYQNENEVGVAI 59
Query: 414 KKLLPKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVH-----NP 578
++ L + +KR ++FI+SKL C Y + + A TLS+L LDY+DLYL+H P
Sbjct: 60 QEKLREQVVKREELFIVSKLW-CTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKP 118
Query: 579 G--IYKLDFENRN---SSRIRKQTWATLVDLYHDHKIRALGVSNY 698
G + LD E+ N S TWA + +L + ++A+G+SN+
Sbjct: 119 GKEFFPLD-ESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNF 162
>J05474-1|AAA51715.1| 316|Homo sapiens aldose reductase protein.
Length = 316
Score = 91.9 bits (218), Expect = 6e-18
Identities = 60/165 (36%), Positives = 91/165 (55%), Gaps = 10/165 (6%)
Frame = +3
Query: 234 LPQQFTLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAF 413
+ + LNNG +MP +GL T+K V + V A+ GYR D A +Y NE + A
Sbjct: 1 MASRLLLNNGAKMPILGLGTWKSPPGQ-VTEAVKVAIDVGYRHIDCAHVYQNENEVGVAI 59
Query: 414 KKLLPKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVH-----NP 578
++ L + +KR ++FI+SKL C Y + + A TLS+L LDY+DLYL+H P
Sbjct: 60 QEKLREQVVKREELFIVSKLW-CTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKP 118
Query: 579 G--IYKLDFENRN---SSRIRKQTWATLVDLYHDHKIRALGVSNY 698
G + LD E+ N S TWA + +L + ++A+G+SN+
Sbjct: 119 GKEFFPLD-ESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNF 162
>J05017-1|AAA51714.1| 316|Homo sapiens ALDR1 protein.
Length = 316
Score = 91.9 bits (218), Expect = 6e-18
Identities = 60/165 (36%), Positives = 91/165 (55%), Gaps = 10/165 (6%)
Frame = +3
Query: 234 LPQQFTLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAF 413
+ + LNNG +MP +GL T+K V + V A+ GYR D A +Y NE + A
Sbjct: 1 MASRILLNNGAKMPILGLGTWKSPPGQ-VTEAVKVAIDVGYRHIDCAHVYQNENEVGVAI 59
Query: 414 KKLLPKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVH-----NP 578
++ L + +KR ++FI+SKL C Y + + A TLS+L LDY+DLYL+H P
Sbjct: 60 QEKLREQVVKREELFIVSKLW-CTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKP 118
Query: 579 G--IYKLDFENRN---SSRIRKQTWATLVDLYHDHKIRALGVSNY 698
G + LD E+ N S TWA + +L + ++A+G+SN+
Sbjct: 119 GKEFFPLD-ESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNF 162
>J04795-1|AAA51713.1| 316|Homo sapiens ALDR1 protein.
Length = 316
Score = 91.9 bits (218), Expect = 6e-18
Identities = 60/165 (36%), Positives = 91/165 (55%), Gaps = 10/165 (6%)
Frame = +3
Query: 234 LPQQFTLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAF 413
+ + LNNG +MP +GL T+K V + V A+ GYR D A +Y NE + A
Sbjct: 1 MASRLLLNNGAKMPILGLGTWKSPPGQ-VTEAVKVAIDVGYRHIDCAHVYQNENEVGVAI 59
Query: 414 KKLLPKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVH-----NP 578
++ L + +KR ++FI+SKL C Y + + A TLS+L LDY+DLYL+H P
Sbjct: 60 QEKLREQVVKREELFIVSKLW-CTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKP 118
Query: 579 G--IYKLDFENRN---SSRIRKQTWATLVDLYHDHKIRALGVSNY 698
G + LD E+ N S TWA + +L + ++A+G+SN+
Sbjct: 119 GKEFFPLD-ESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNF 162
>CR542203-1|CAG47000.1| 316|Homo sapiens AKR1B1 protein.
Length = 316
Score = 91.9 bits (218), Expect = 6e-18
Identities = 60/165 (36%), Positives = 91/165 (55%), Gaps = 10/165 (6%)
Frame = +3
Query: 234 LPQQFTLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAF 413
+ + LNNG +MP +GL T+K V + V A+ GYR D A +Y NE + A
Sbjct: 1 MASRLLLNNGAKMPILGLGTWKSPPGQ-VTEAVKVAIDVGYRHIDCAHVYQNENEVGVAI 59
Query: 414 KKLLPKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVH-----NP 578
++ L + +KR ++FI+SKL C Y + + A TLS+L LDY+DLYL+H P
Sbjct: 60 QEKLREQVVKREELFIVSKLW-CTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPIGFKP 118
Query: 579 G--IYKLDFENRN---SSRIRKQTWATLVDLYHDHKIRALGVSNY 698
G + LD E+ N S TWA + +L + ++A+G+SN+
Sbjct: 119 GKEFFPLD-ESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNF 162
>CR450351-1|CAG29347.1| 316|Homo sapiens AKR1B1 protein.
Length = 316
Score = 91.9 bits (218), Expect = 6e-18
Identities = 60/165 (36%), Positives = 91/165 (55%), Gaps = 10/165 (6%)
Frame = +3
Query: 234 LPQQFTLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAF 413
+ + LNNG +MP +GL T+K V + V A+ GYR D A +Y NE + A
Sbjct: 1 MASRLLLNNGAKMPILGLGTWKSPPGQ-VTEAVKVAIDVGYRHIDCAHVYQNENEVGVAI 59
Query: 414 KKLLPKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVH-----NP 578
++ L + +KR ++FI+SKL C Y + + A TLS+L LDY+DLYL+H P
Sbjct: 60 QEKLREQVVKREELFIVSKLW-CTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFRP 118
Query: 579 G--IYKLDFENRN---SSRIRKQTWATLVDLYHDHKIRALGVSNY 698
G + LD E+ N S TWA + +L + ++A+G+SN+
Sbjct: 119 GKEFFPLD-ESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNF 162
>BT019859-1|AAV38662.1| 316|Homo sapiens aldo-keto reductase family
1, member B1 (aldose reductase) protein.
Length = 316
Score = 91.9 bits (218), Expect = 6e-18
Identities = 60/165 (36%), Positives = 91/165 (55%), Gaps = 10/165 (6%)
Frame = +3
Query: 234 LPQQFTLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAF 413
+ + LNNG +MP +GL T+K V + V A+ GYR D A +Y NE + A
Sbjct: 1 MASRLLLNNGAKMPILGLGTWKSPPGQ-VTEAVKVAIDVGYRHIDCAHVYQNENEVGVAI 59
Query: 414 KKLLPKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVH-----NP 578
++ L + +KR ++FI+SKL C Y + + A TLS+L LDY+DLYL+H P
Sbjct: 60 QEKLREQVVKREELFIVSKLW-CTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKP 118
Query: 579 G--IYKLDFENRN---SSRIRKQTWATLVDLYHDHKIRALGVSNY 698
G + LD E+ N S TWA + +L + ++A+G+SN+
Sbjct: 119 GKEFFPLD-ESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNF 162
>BC010391-1|AAH10391.1| 316|Homo sapiens aldo-keto reductase family
1, member B1 (aldose reductase) protein.
Length = 316
Score = 91.9 bits (218), Expect = 6e-18
Identities = 60/165 (36%), Positives = 91/165 (55%), Gaps = 10/165 (6%)
Frame = +3
Query: 234 LPQQFTLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAF 413
+ + LNNG +MP +GL T+K V + V A+ GYR D A +Y NE + A
Sbjct: 1 MASRLLLNNGAKMPILGLGTWKSPPGQ-VTEAVKVAIDVGYRHIDCAHVYQNENEVGVAI 59
Query: 414 KKLLPKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVH-----NP 578
++ L + +KR ++FI+SKL C Y + + A TLS+L LDY+DLYL+H P
Sbjct: 60 QEKLREQVVKREELFIVSKLW-CTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKP 118
Query: 579 G--IYKLDFENRN---SSRIRKQTWATLVDLYHDHKIRALGVSNY 698
G + LD E+ N S TWA + +L + ++A+G+SN+
Sbjct: 119 GKEFFPLD-ESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNF 162
>BC000260-1|AAH00260.1| 316|Homo sapiens aldo-keto reductase family
1, member B1 (aldose reductase) protein.
Length = 316
Score = 91.9 bits (218), Expect = 6e-18
Identities = 60/165 (36%), Positives = 91/165 (55%), Gaps = 10/165 (6%)
Frame = +3
Query: 234 LPQQFTLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAF 413
+ + LNNG +MP +GL T+K V + V A+ GYR D A +Y NE + A
Sbjct: 1 MASRLLLNNGAKMPILGLGTWKSPPGQ-VTEAVKVAIDVGYRHIDCAHVYQNENEVGVAI 59
Query: 414 KKLLPKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVH-----NP 578
++ L + +KR ++FI+SKL C Y + + A TLS+L LDY+DLYL+H P
Sbjct: 60 QEKLREQVVKREELFIVSKLW-CTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKP 118
Query: 579 G--IYKLDFENRN---SSRIRKQTWATLVDLYHDHKIRALGVSNY 698
G + LD E+ N S TWA + +L + ++A+G+SN+
Sbjct: 119 GKEFFPLD-ESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNF 162
>AF328729-1|AAN09721.1| 316|Homo sapiens CTCL tumor antigen
HD-CL-07 protein.
Length = 316
Score = 91.9 bits (218), Expect = 6e-18
Identities = 60/165 (36%), Positives = 91/165 (55%), Gaps = 10/165 (6%)
Frame = +3
Query: 234 LPQQFTLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAF 413
+ + LNNG +MP +GL T+K V + V A+ GYR D A +Y NE + A
Sbjct: 1 MASRLLLNNGAKMPILGLGTWKSPPGQ-VTEAVKVAIDVGYRHIDCAHVYQNENEVGVAI 59
Query: 414 KKLLPKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVH-----NP 578
++ L + +KR ++FI+SKL C Y + + A TLS+L LDY+DLYL+H P
Sbjct: 60 QEKLREQVVKREELFIVSKLW-CTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKP 118
Query: 579 G--IYKLDFENRN---SSRIRKQTWATLVDLYHDHKIRALGVSNY 698
G + LD E+ N S TWA + +L + ++A+G+SN+
Sbjct: 119 GKEFFPLD-ESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNF 162
>AF032455-1|AAB88851.1| 316|Homo sapiens aldose reductase protein.
Length = 316
Score = 91.9 bits (218), Expect = 6e-18
Identities = 60/165 (36%), Positives = 91/165 (55%), Gaps = 10/165 (6%)
Frame = +3
Query: 234 LPQQFTLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAF 413
+ + LNNG +MP +GL T+K V + V A+ GYR D A +Y NE + A
Sbjct: 1 MASRLLLNNGAKMPILGLGTWKSPPGQ-VTEAVKVAIDVGYRHIDCAHVYQNENEVGVAI 59
Query: 414 KKLLPKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVH-----NP 578
++ L + +KR ++FI+SKL C Y + + A TLS+L LDY+DLYL+H P
Sbjct: 60 QEKLREQVVKREELFIVSKLW-CTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKP 118
Query: 579 G--IYKLDFENRN---SSRIRKQTWATLVDLYHDHKIRALGVSNY 698
G + LD E+ N S TWA + +L + ++A+G+SN+
Sbjct: 119 GKEFFPLD-ESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNF 162
>AB209796-1|BAD93033.1| 260|Homo sapiens aldo-keto reductase family
1, member B1 variant protein.
Length = 260
Score = 91.5 bits (217), Expect = 7e-18
Identities = 60/159 (37%), Positives = 89/159 (55%), Gaps = 10/159 (6%)
Frame = +3
Query: 252 LNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPK 431
LNNG +MP +GL T+K V + V A+ GYR D A +Y NE + A ++ L +
Sbjct: 4 LNNGAKMPILGLGTWKSPPGQ-VTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLRE 62
Query: 432 YKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVH-----NPG--IYK 590
+KR ++FI+SKL C Y + + A TLS+L LDY+DLYL+H PG +
Sbjct: 63 QVVKREELFIVSKLW-CTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFP 121
Query: 591 LDFENRN---SSRIRKQTWATLVDLYHDHKIRALGVSNY 698
LD E+ N S TWA + +L + ++A+G+SN+
Sbjct: 122 LD-ESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNF 159
>BC005387-1|AAH05387.1| 316|Homo sapiens aldo-keto reductase family
1, member B1 (aldose reductase) protein.
Length = 316
Score = 86.2 bits (204), Expect = 3e-16
Identities = 59/165 (35%), Positives = 90/165 (54%), Gaps = 10/165 (6%)
Frame = +3
Query: 234 LPQQFTLNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAF 413
+ + LNNG +MP +GL T+K V + V A+ GYR D A +Y NE + A
Sbjct: 1 MASRLLLNNGAKMPILGLGTWKSPPGQ-VTEAVKVAIDVGYRHIDCAHVYQNENEVGVAI 59
Query: 414 KKLLPKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVH-----NP 578
++ L + +KR ++FI+SKL C Y + + A TLS+L LDY+DLYL+H P
Sbjct: 60 QEKLREQVVKREELFIVSKLW-CTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKP 118
Query: 579 G--IYKLDFENRN---SSRIRKQTWATLVDLYHDHKIRALGVSNY 698
G + LD E+ N S T A + +L + ++A+G+SN+
Sbjct: 119 GKEFFPLD-ESGNVVPSDTNILDTRAAMEELVDEGLVKAIGISNF 162
>U37100-1|AAC17469.1| 316|Homo sapiens aldose reductase-like
peptide protein.
Length = 316
Score = 80.2 bits (189), Expect = 2e-14
Identities = 52/158 (32%), Positives = 86/158 (54%), Gaps = 9/158 (5%)
Frame = +3
Query: 252 LNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPK 431
L+ +MP +GL T+K V + V A+ AGYR D A +Y NE + A ++ + +
Sbjct: 7 LSTKAKMPIVGLGTWK-SPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEKIQE 65
Query: 432 YKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYK-----LD 596
+KR D+FI+SKL P + + +AF TL +L L Y+D+YL+H P +K
Sbjct: 66 KAVKREDLFIVSKLWP-TFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGDDLFP 124
Query: 597 FENRNSSRIRKQT----WATLVDLYHDHKIRALGVSNY 698
+++ ++ K T W + +L + ++ALGVSN+
Sbjct: 125 KDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNF 162
>CR541801-1|CAG46600.1| 316|Homo sapiens AKR1B10 protein.
Length = 316
Score = 80.2 bits (189), Expect = 2e-14
Identities = 52/158 (32%), Positives = 86/158 (54%), Gaps = 9/158 (5%)
Frame = +3
Query: 252 LNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPK 431
L+ +MP +GL T+K V + V A+ AGYR D A +Y NE + A ++ + +
Sbjct: 7 LSTKAKMPIVGLGTWK-SPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEKIQE 65
Query: 432 YKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYK-----LD 596
+KR D+FI+SKL P + + +AF TL +L L Y+D+YL+H P +K
Sbjct: 66 KAVKREDLFIVSKLWP-TFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGDDLFP 124
Query: 597 FENRNSSRIRKQT----WATLVDLYHDHKIRALGVSNY 698
+++ ++ K T W + +L + ++ALGVSN+
Sbjct: 125 KDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNF 162
>BT006794-1|AAP35440.1| 316|Homo sapiens aldo-keto reductase family
1, member B10 (aldose reductase) protein.
Length = 316
Score = 80.2 bits (189), Expect = 2e-14
Identities = 52/158 (32%), Positives = 86/158 (54%), Gaps = 9/158 (5%)
Frame = +3
Query: 252 LNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPK 431
L+ +MP +GL T+K V + V A+ AGYR D A +Y NE + A ++ + +
Sbjct: 7 LSTKAKMPIVGLGTWK-SPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEKIQE 65
Query: 432 YKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYK-----LD 596
+KR D+FI+SKL P + + +AF TL +L L Y+D+YL+H P +K
Sbjct: 66 KAVKREDLFIVSKLWP-TFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGDDLFP 124
Query: 597 FENRNSSRIRKQT----WATLVDLYHDHKIRALGVSNY 698
+++ ++ K T W + +L + ++ALGVSN+
Sbjct: 125 KDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNF 162
>BC008837-1|AAH08837.1| 316|Homo sapiens aldo-keto reductase family
1, member B10 (aldose reductase) protein.
Length = 316
Score = 80.2 bits (189), Expect = 2e-14
Identities = 52/158 (32%), Positives = 86/158 (54%), Gaps = 9/158 (5%)
Frame = +3
Query: 252 LNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPK 431
L+ +MP +GL T+K V + V A+ AGYR D A +Y NE + A ++ + +
Sbjct: 7 LSTKAKMPIVGLGTWK-SPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEKIQE 65
Query: 432 YKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYK-----LD 596
+KR D+FI+SKL P + + +AF TL +L L Y+D+YL+H P +K
Sbjct: 66 KAVKREDLFIVSKLWP-TFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGDDLFP 124
Query: 597 FENRNSSRIRKQT----WATLVDLYHDHKIRALGVSNY 698
+++ ++ K T W + +L + ++ALGVSN+
Sbjct: 125 KDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNF 162
>AF052577-1|AAC36465.1| 316|Homo sapiens aldo-keto reductase
protein.
Length = 316
Score = 80.2 bits (189), Expect = 2e-14
Identities = 52/158 (32%), Positives = 86/158 (54%), Gaps = 9/158 (5%)
Frame = +3
Query: 252 LNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPK 431
L+ +MP +GL T+K V + V A+ AGYR D A +Y NE + A ++ + +
Sbjct: 7 LSTKAKMPIVGLGTWK-SPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEKIQE 65
Query: 432 YKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYK-----LD 596
+KR D+FI+SKL P + + +AF TL +L L Y+D+YL+H P +K
Sbjct: 66 KAVKREDLFIVSKLWP-TFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGDDLFP 124
Query: 597 FENRNSSRIRKQT----WATLVDLYHDHKIRALGVSNY 698
+++ ++ K T W + +L + ++ALGVSN+
Sbjct: 125 KDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNF 162
>AF524864-1|AAO13380.1| 316|Homo sapiens aldo-ketoreductase
protein.
Length = 316
Score = 75.8 bits (178), Expect = 4e-13
Identities = 51/158 (32%), Positives = 84/158 (53%), Gaps = 9/158 (5%)
Frame = +3
Query: 252 LNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPK 431
L+ +MP +GL T+K V + V A+ AGYR D A +Y NE + A ++ + +
Sbjct: 7 LSTKAKMPIVGLGTWK-SPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEKIQE 65
Query: 432 YKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYK-----LD 596
+KR D+FI SKL P + + +AF TL + L Y+D+YL+H P +K
Sbjct: 66 KAVKREDLFIASKLWP-TFFERPLVRKAFEKTLKDPKLSYLDVYLIHWPQGFKSGDDLFP 124
Query: 597 FENRNSSRIRKQT----WATLVDLYHDHKIRALGVSNY 698
+++ ++ K T W + +L + ++ALGVSN+
Sbjct: 125 KDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNF 162
>J04794-1|AAA51711.1| 325|Homo sapiens ALDR1 protein.
Length = 325
Score = 75.4 bits (177), Expect = 5e-13
Identities = 58/159 (36%), Positives = 80/159 (50%), Gaps = 10/159 (6%)
Frame = +3
Query: 252 LNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKK-LLP 428
L+ G +MP IGL T+K V V AL GYR D AA+YGNE + A K+ + P
Sbjct: 8 LHTGQKMPLIGLGTWK-SEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALKEDVGP 66
Query: 429 KYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVH---------NPG 581
+ R ++F+ SKL + V E A TL++L L+Y+DLYL+H NP
Sbjct: 67 GKAVPREELFVTSKLWNTKHHPEDV-EPALRKTLADLQLEYLDLYLMHWPYAFERGDNPF 125
Query: 582 IYKLDFENRNSSRIRKQTWATLVDLYHDHKIRALGVSNY 698
D S K+TW L L ++ALG+SN+
Sbjct: 126 PKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNF 164
>CR457010-1|CAG33291.1| 325|Homo sapiens AKR1A1 protein.
Length = 325
Score = 75.4 bits (177), Expect = 5e-13
Identities = 58/159 (36%), Positives = 80/159 (50%), Gaps = 10/159 (6%)
Frame = +3
Query: 252 LNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKK-LLP 428
L+ G +MP IGL T+K V V AL GYR D AA+YGNE + A K+ + P
Sbjct: 8 LHTGQKMPLIGLGTWK-SEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALKEDVGP 66
Query: 429 KYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVH---------NPG 581
+ R ++F+ SKL + V E A TL++L L+Y+DLYL+H NP
Sbjct: 67 GKAVPREELFVTSKLWNTKHHPEDV-EPALRKTLADLQLEYLDLYLMHWPYAFERGDNPF 125
Query: 582 IYKLDFENRNSSRIRKQTWATLVDLYHDHKIRALGVSNY 698
D S K+TW L L ++ALG+SN+
Sbjct: 126 PKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNF 164
>BT007003-1|AAP35649.1| 325|Homo sapiens aldo-keto reductase family
1, member A1 (aldehyde reductase) protein.
Length = 325
Score = 75.4 bits (177), Expect = 5e-13
Identities = 58/159 (36%), Positives = 80/159 (50%), Gaps = 10/159 (6%)
Frame = +3
Query: 252 LNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKK-LLP 428
L+ G +MP IGL T+K V V AL GYR D AA+YGNE + A K+ + P
Sbjct: 8 LHTGQKMPLIGLGTWK-SEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALKEDVGP 66
Query: 429 KYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVH---------NPG 581
+ R ++F+ SKL + V E A TL++L L+Y+DLYL+H NP
Sbjct: 67 GKAVPREELFVTSKLWNTKHHPEDV-EPALRKTLADLQLEYLDLYLMHWPYAFERGDNPF 125
Query: 582 IYKLDFENRNSSRIRKQTWATLVDLYHDHKIRALGVSNY 698
D S K+TW L L ++ALG+SN+
Sbjct: 126 PKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNF 164
>BC005394-1|AAH05394.1| 325|Homo sapiens aldo-keto reductase family
1, member A1 (aldehyde reductase) protein.
Length = 325
Score = 75.4 bits (177), Expect = 5e-13
Identities = 58/159 (36%), Positives = 80/159 (50%), Gaps = 10/159 (6%)
Frame = +3
Query: 252 LNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKK-LLP 428
L+ G +MP IGL T+K V V AL GYR D AA+YGNE + A K+ + P
Sbjct: 8 LHTGQKMPLIGLGTWK-SEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALKEDVGP 66
Query: 429 KYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVH---------NPG 581
+ R ++F+ SKL + V E A TL++L L+Y+DLYL+H NP
Sbjct: 67 GKAVPREELFVTSKLWNTKHHPEDV-EPALRKTLADLQLEYLDLYLMHWPYAFERGDNPF 125
Query: 582 IYKLDFENRNSSRIRKQTWATLVDLYHDHKIRALGVSNY 698
D S K+TW L L ++ALG+SN+
Sbjct: 126 PKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNF 164
>BC000670-1|AAH00670.1| 325|Homo sapiens aldo-keto reductase family
1, member A1 (aldehyde reductase) protein.
Length = 325
Score = 75.4 bits (177), Expect = 5e-13
Identities = 58/159 (36%), Positives = 80/159 (50%), Gaps = 10/159 (6%)
Frame = +3
Query: 252 LNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKK-LLP 428
L+ G +MP IGL T+K V V AL GYR D AA+YGNE + A K+ + P
Sbjct: 8 LHTGQKMPLIGLGTWK-SEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALKEDVGP 66
Query: 429 KYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVH---------NPG 581
+ R ++F+ SKL + V E A TL++L L+Y+DLYL+H NP
Sbjct: 67 GKAVPREELFVTSKLWNTKHHPEDV-EPALRKTLADLQLEYLDLYLMHWPYAFERGDNPF 125
Query: 582 IYKLDFENRNSSRIRKQTWATLVDLYHDHKIRALGVSNY 698
D S K+TW L L ++ALG+SN+
Sbjct: 126 PKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNF 164
>AL355480-3|CAI22459.1| 325|Homo sapiens aldo-keto reductase family
1, member A1 (aldehydetase, 1 protein.
Length = 325
Score = 75.4 bits (177), Expect = 5e-13
Identities = 58/159 (36%), Positives = 80/159 (50%), Gaps = 10/159 (6%)
Frame = +3
Query: 252 LNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKK-LLP 428
L+ G +MP IGL T+K V V AL GYR D AA+YGNE + A K+ + P
Sbjct: 8 LHTGQKMPLIGLGTWK-SEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALKEDVGP 66
Query: 429 KYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVH---------NPG 581
+ R ++F+ SKL + V E A TL++L L+Y+DLYL+H NP
Sbjct: 67 GKAVPREELFVTSKLWNTKHHPEDV-EPALRKTLADLQLEYLDLYLMHWPYAFERGDNPF 125
Query: 582 IYKLDFENRNSSRIRKQTWATLVDLYHDHKIRALGVSNY 698
D S K+TW L L ++ALG+SN+
Sbjct: 126 PKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNF 164
>AF112485-1|AAF01260.1| 325|Homo sapiens aldehyde reductase
protein.
Length = 325
Score = 75.4 bits (177), Expect = 5e-13
Identities = 58/159 (36%), Positives = 80/159 (50%), Gaps = 10/159 (6%)
Frame = +3
Query: 252 LNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKK-LLP 428
L+ G +MP IGL T+K V V AL GYR D AA+YGNE + A K+ + P
Sbjct: 8 LHTGQKMPLIGLGTWK-SEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALKEDVGP 66
Query: 429 KYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVH---------NPG 581
+ R ++F+ SKL + V E A TL++L L+Y+DLYL+H NP
Sbjct: 67 GKAVPREELFVTSKLWNTKHHPEDV-EPALRKTLADLQLEYLDLYLMHWPYAFERGDNPF 125
Query: 582 IYKLDFENRNSSRIRKQTWATLVDLYHDHKIRALGVSNY 698
D S K+TW L L ++ALG+SN+
Sbjct: 126 PKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNF 164
>AF036683-1|AAB92369.1| 325|Homo sapiens aldehyde reductase
protein.
Length = 325
Score = 75.4 bits (177), Expect = 5e-13
Identities = 58/159 (36%), Positives = 80/159 (50%), Gaps = 10/159 (6%)
Frame = +3
Query: 252 LNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKK-LLP 428
L+ G +MP IGL T+K V V AL GYR D AA+YGNE + A K+ + P
Sbjct: 8 LHTGQKMPLIGLGTWK-SEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALKEDVGP 66
Query: 429 KYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVH---------NPG 581
+ R ++F+ SKL + V E A TL++L L+Y+DLYL+H NP
Sbjct: 67 GKAVPREELFVTSKLWNTKHHPEDV-EPALRKTLADLQLEYLDLYLMHWPYAFERGDNPF 125
Query: 582 IYKLDFENRNSSRIRKQTWATLVDLYHDHKIRALGVSNY 698
D S K+TW L L ++ALG+SN+
Sbjct: 126 PKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNF 164
>U05861-1|AAA18115.1| 323|Homo sapiens hepatic dihydrodiol
dehydrogenase protein.
Length = 323
Score = 74.1 bits (174), Expect = 1e-12
Identities = 46/122 (37%), Positives = 62/122 (50%), Gaps = 2/122 (1%)
Frame = +3
Query: 219 DFKYILPQQFTLNNGVEMPAIGLDTFKMGHF--YTVLQTVDDALKAGYRMFDTAALYGNE 392
D KY Q LN+G MP +G T+ L+ A++AG+R D+A LY NE
Sbjct: 2 DSKY---QCVKLNDGHFMPVLGFGTYAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNE 58
Query: 393 VYLNFAFKKLLPKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVH 572
+ A + + +KR DIF SKL CN + A +L NL LDY+DLYL+H
Sbjct: 59 EQVGLAIRSKIADGSVKREDIFYTSKLW-CNSHRPELVRPALERSLKNLQLDYVDLYLIH 117
Query: 573 NP 578
P
Sbjct: 118 FP 119
>U05684-1|AAA16227.1| 323|Homo sapiens dihydrodiol dehydrogenase
protein.
Length = 323
Score = 74.1 bits (174), Expect = 1e-12
Identities = 46/122 (37%), Positives = 62/122 (50%), Gaps = 2/122 (1%)
Frame = +3
Query: 219 DFKYILPQQFTLNNGVEMPAIGLDTFKMGHF--YTVLQTVDDALKAGYRMFDTAALYGNE 392
D KY Q LN+G MP +G T+ L+ A++AG+R D+A LY NE
Sbjct: 2 DSKY---QCVKLNDGHFMPVLGFGTYAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNE 58
Query: 393 VYLNFAFKKLLPKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVH 572
+ A + + +KR DIF SKL CN + A +L NL LDY+DLYL+H
Sbjct: 59 EQVGLAIRSKIADGSVKREDIFYTSKLW-CNSHRPELVRPALERSLKNLQLDYVDLYLIH 117
Query: 573 NP 578
P
Sbjct: 118 FP 119
>M86609-1|AAB02880.1| 323|Homo sapiens dihydrodiol dehydrogenase
protein.
Length = 323
Score = 74.1 bits (174), Expect = 1e-12
Identities = 46/122 (37%), Positives = 62/122 (50%), Gaps = 2/122 (1%)
Frame = +3
Query: 219 DFKYILPQQFTLNNGVEMPAIGLDTFKMGHF--YTVLQTVDDALKAGYRMFDTAALYGNE 392
D KY Q LN+G MP +G T+ L+ A++AG+R D+A LY NE
Sbjct: 2 DSKY---QCVKLNDGHFMPVLGFGTYAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNE 58
Query: 393 VYLNFAFKKLLPKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVH 572
+ A + + +KR DIF SKL CN + A +L NL LDY+DLYL+H
Sbjct: 59 EQVGLAIRSKIADGSVKREDIFYTSKLW-CNSHRPELVRPALERSLKNLQLDYVDLYLIH 117
Query: 573 NP 578
P
Sbjct: 118 FP 119
>BT007197-1|AAP35861.1| 323|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 323
Score = 74.1 bits (174), Expect = 1e-12
Identities = 46/122 (37%), Positives = 62/122 (50%), Gaps = 2/122 (1%)
Frame = +3
Query: 219 DFKYILPQQFTLNNGVEMPAIGLDTFKMGHF--YTVLQTVDDALKAGYRMFDTAALYGNE 392
D KY Q LN+G MP +G T+ L+ A++AG+R D+A LY NE
Sbjct: 2 DSKY---QCVKLNDGHFMPVLGFGTYAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNE 58
Query: 393 VYLNFAFKKLLPKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVH 572
+ A + + +KR DIF SKL CN + A +L NL LDY+DLYL+H
Sbjct: 59 EQVGLAIRSKIADGSVKREDIFYTSKLW-CNSHRPELVRPALERSLKNLQLDYVDLYLIH 117
Query: 573 NP 578
P
Sbjct: 118 FP 119
>BC040210-1|AAH40210.1| 323|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 323
Score = 74.1 bits (174), Expect = 1e-12
Identities = 46/122 (37%), Positives = 62/122 (50%), Gaps = 2/122 (1%)
Frame = +3
Query: 219 DFKYILPQQFTLNNGVEMPAIGLDTFKMGHF--YTVLQTVDDALKAGYRMFDTAALYGNE 392
D KY Q LN+G MP +G T+ L+ A++AG+R D+A LY NE
Sbjct: 2 DSKY---QCVKLNDGHFMPVLGFGTYAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNE 58
Query: 393 VYLNFAFKKLLPKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVH 572
+ A + + +KR DIF SKL CN + A +L NL LDY+DLYL+H
Sbjct: 59 EQVGLAIRSKIADGSVKREDIFYTSKLW-CNSHRPELVRPALERSLKNLQLDYVDLYLIH 117
Query: 573 NP 578
P
Sbjct: 118 FP 119
>BC020216-1|AAH20216.1| 323|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 323
Score = 74.1 bits (174), Expect = 1e-12
Identities = 46/122 (37%), Positives = 62/122 (50%), Gaps = 2/122 (1%)
Frame = +3
Query: 219 DFKYILPQQFTLNNGVEMPAIGLDTFKMGHF--YTVLQTVDDALKAGYRMFDTAALYGNE 392
D KY Q LN+G MP +G T+ L+ A++AG+R D+A LY NE
Sbjct: 2 DSKY---QCVKLNDGHFMPVLGFGTYAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNE 58
Query: 393 VYLNFAFKKLLPKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVH 572
+ A + + +KR DIF SKL CN + A +L NL LDY+DLYL+H
Sbjct: 59 EQVGLAIRSKIADGSVKREDIFYTSKLW-CNSHRPELVRPALERSLKNLQLDYVDLYLIH 117
Query: 573 NP 578
P
Sbjct: 118 FP 119
>BC015490-1|AAH15490.1| 323|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 323
Score = 74.1 bits (174), Expect = 1e-12
Identities = 46/122 (37%), Positives = 62/122 (50%), Gaps = 2/122 (1%)
Frame = +3
Query: 219 DFKYILPQQFTLNNGVEMPAIGLDTFKMGHF--YTVLQTVDDALKAGYRMFDTAALYGNE 392
D KY Q LN+G MP +G T+ L+ A++AG+R D+A LY NE
Sbjct: 2 DSKY---QCVKLNDGHFMPVLGFGTYAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNE 58
Query: 393 VYLNFAFKKLLPKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVH 572
+ A + + +KR DIF SKL CN + A +L NL LDY+DLYL+H
Sbjct: 59 EQVGLAIRSKIADGSVKREDIFYTSKLW-CNSHRPELVRPALERSLKNLQLDYVDLYLIH 117
Query: 573 NP 578
P
Sbjct: 118 FP 119
>AL713867-2|CAI16409.1| 323|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 323
Score = 74.1 bits (174), Expect = 1e-12
Identities = 46/122 (37%), Positives = 62/122 (50%), Gaps = 2/122 (1%)
Frame = +3
Query: 219 DFKYILPQQFTLNNGVEMPAIGLDTFKMGHF--YTVLQTVDDALKAGYRMFDTAALYGNE 392
D KY Q LN+G MP +G T+ L+ A++AG+R D+A LY NE
Sbjct: 2 DSKY---QCVKLNDGHFMPVLGFGTYAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNE 58
Query: 393 VYLNFAFKKLLPKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVH 572
+ A + + +KR DIF SKL CN + A +L NL LDY+DLYL+H
Sbjct: 59 EQVGLAIRSKIADGSVKREDIFYTSKLW-CNSHRPELVRPALERSLKNLQLDYVDLYLIH 117
Query: 573 NP 578
P
Sbjct: 118 FP 119
>AB032150-1|BAA92886.1| 323|Homo sapiens 20 alph-hydroxysteroid
dehydrogenase protein.
Length = 323
Score = 74.1 bits (174), Expect = 1e-12
Identities = 46/122 (37%), Positives = 62/122 (50%), Gaps = 2/122 (1%)
Frame = +3
Query: 219 DFKYILPQQFTLNNGVEMPAIGLDTFKMGHF--YTVLQTVDDALKAGYRMFDTAALYGNE 392
D KY Q LN+G MP +G T+ L+ A++AG+R D+A LY NE
Sbjct: 2 DSKY---QCVKLNDGHFMPVLGFGTYAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNE 58
Query: 393 VYLNFAFKKLLPKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVH 572
+ A + + +KR DIF SKL CN + A +L NL LDY+DLYL+H
Sbjct: 59 EQVGLAIRSKIADGSVKREDIFYTSKLW-CNSHRPELVRPALERSLKNLQLDYVDLYLIH 117
Query: 573 NP 578
P
Sbjct: 118 FP 119
>AB031083-1|BAA92883.1| 323|Homo sapiens 20 alpha-hydroxysteroid
dehydrogenase protein.
Length = 323
Score = 74.1 bits (174), Expect = 1e-12
Identities = 46/122 (37%), Positives = 62/122 (50%), Gaps = 2/122 (1%)
Frame = +3
Query: 219 DFKYILPQQFTLNNGVEMPAIGLDTFKMGHF--YTVLQTVDDALKAGYRMFDTAALYGNE 392
D KY Q LN+G MP +G T+ L+ A++AG+R D+A LY NE
Sbjct: 2 DSKY---QCVKLNDGHFMPVLGFGTYAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNE 58
Query: 393 VYLNFAFKKLLPKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVH 572
+ A + + +KR DIF SKL CN + A +L NL LDY+DLYL+H
Sbjct: 59 EQVGLAIRSKIADGSVKREDIFYTSKLW-CNSHRPELVRPALERSLKNLQLDYVDLYLIH 117
Query: 573 NP 578
P
Sbjct: 118 FP 119
>S68290-1|AAD14012.1| 320|Homo sapiens chlordecone reductase
homolog protein.
Length = 320
Score = 73.3 bits (172), Expect = 2e-12
Identities = 42/111 (37%), Positives = 58/111 (52%), Gaps = 2/111 (1%)
Frame = +3
Query: 252 LNNGVEMPAIGLDTFKMGHF--YTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLL 425
LN+G MP +G T+ L+ A++AG+R D+A LY NE + A + +
Sbjct: 7 LNDGHFMPVLGFGTYAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKI 66
Query: 426 PKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNP 578
+KR DIF SKL CN + A +L NL LDY+DLYL+H P
Sbjct: 67 ADGSVKREDIFYTSKLW-CNSHRPELDRPALERSLKNLQLDYVDLYLIHFP 116
>S68287-1|AAD14010.1| 323|Homo sapiens chlordecone reductase
protein.
Length = 323
Score = 70.5 bits (165), Expect = 1e-11
Identities = 40/115 (34%), Positives = 61/115 (53%), Gaps = 2/115 (1%)
Frame = +3
Query: 240 QQFTLNNGVEMPAIGLDTFKMGHF--YTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAF 413
Q+ LN+G MP +G T+ ++ A++AG+R D+A LY NE + A
Sbjct: 6 QRVELNDGHFMPVLGFGTYAPPEVPRNRAVEVTKLAIEAGFRHIDSAYLYNNEEQVGLAI 65
Query: 414 KKLLPKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNP 578
+ + +KR DIF SKL C + + + A ++L L LDY+DLYL+H P
Sbjct: 66 RSKIADGSVKREDIFYTSKLW-CTFFQPQMVQPALESSLKKLQLDYVDLYLLHFP 119
>D26125-1|BAA05122.1| 321|Homo sapiens 3
alpha-hydroxysteroid/dihydrodiol dehydrogenase DD4
protein.
Length = 321
Score = 70.5 bits (165), Expect = 1e-11
Identities = 40/115 (34%), Positives = 61/115 (53%), Gaps = 2/115 (1%)
Frame = +3
Query: 240 QQFTLNNGVEMPAIGLDTFKMGHF--YTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAF 413
Q+ LN+G MP +G T+ ++ A++AG+R D+A LY NE + A
Sbjct: 4 QRVELNDGHFMPVLGFGTYAPPEVPRNRAVEVTKLAIEAGFRHIDSAYLYNNEEQVGLAI 63
Query: 414 KKLLPKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNP 578
+ + +KR DIF SKL C + + + A ++L L LDY+DLYL+H P
Sbjct: 64 RSKIADGSVKREDIFYTSKLW-CTFFQPQMVQPALESSLKKLQLDYVDLYLLHFP 117
>DQ269985-1|ABB76132.1| 323|Homo sapiens type II 3a-hydroxysteroid
dehydrogenase variant protein.
Length = 323
Score = 70.5 bits (165), Expect = 1e-11
Identities = 40/111 (36%), Positives = 57/111 (51%), Gaps = 2/111 (1%)
Frame = +3
Query: 252 LNNGVEMPAIGLDTFKMGHF--YTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLL 425
LN+G MP +G T+ L+ A++AG+R D+A LY NE + A + +
Sbjct: 10 LNDGHFMPVLGFGTYAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAVRSKI 69
Query: 426 PKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNP 578
+KR DIF SKL CN + A +L LDY+DLYL+H+P
Sbjct: 70 ADGSVKREDIFYTSKLW-CNSHRPELVRPALERSLKKAQLDYVDLYLIHSP 119
>BC020744-1|AAH20744.1| 323|Homo sapiens aldo-keto reductase family
1, member C4 (chlordecone reductase; 3-alpha hydroxy
protein.
Length = 323
Score = 70.5 bits (165), Expect = 1e-11
Identities = 40/115 (34%), Positives = 61/115 (53%), Gaps = 2/115 (1%)
Frame = +3
Query: 240 QQFTLNNGVEMPAIGLDTFKMGHF--YTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAF 413
Q+ LN+G MP +G T+ ++ A++AG+R D+A LY NE + A
Sbjct: 6 QRVELNDGHFMPVLGFGTYAPPEVPRNRAVEVTKLAIEAGFRHIDSAYLYNNEEQVGLAI 65
Query: 414 KKLLPKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNP 578
+ + +KR DIF SKL C + + + A ++L L LDY+DLYL+H P
Sbjct: 66 RSKIADGSVKREDIFYTSKLW-CTFFQPQMVQPALESSLKKLQLDYVDLYLLHFP 119
>AL355303-2|CAI14202.1| 323|Homo sapiens aldo-keto reductase family
1, member C4 (chlordecone reductase; 3-alpha hydroxy
protein.
Length = 323
Score = 70.5 bits (165), Expect = 1e-11
Identities = 40/115 (34%), Positives = 61/115 (53%), Gaps = 2/115 (1%)
Frame = +3
Query: 240 QQFTLNNGVEMPAIGLDTFKMGHF--YTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAF 413
Q+ LN+G MP +G T+ ++ A++AG+R D+A LY NE + A
Sbjct: 6 QRVELNDGHFMPVLGFGTYAPPEVPRNRAVEVTKLAIEAGFRHIDSAYLYNNEEQVGLAI 65
Query: 414 KKLLPKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNP 578
+ + +KR DIF SKL C + + + A ++L L LDY+DLYL+H P
Sbjct: 66 RSKIADGSVKREDIFYTSKLW-CTFFQPQMVQPALESSLKKLQLDYVDLYLLHFP 119
>AB045829-1|BAA99542.1| 323|Homo sapiens 3alpha-hydroxysteroid
dehydrogenase variant protein.
Length = 323
Score = 70.5 bits (165), Expect = 1e-11
Identities = 40/115 (34%), Positives = 61/115 (53%), Gaps = 2/115 (1%)
Frame = +3
Query: 240 QQFTLNNGVEMPAIGLDTFKMGHF--YTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAF 413
Q+ LN+G MP +G T+ ++ A++AG+R D+A LY NE + A
Sbjct: 6 QRVELNDGHFMPVLGFGTYAPPEVPRNRAVEVTKLAIEAGFRHIDSAYLYNNEEQVGLAI 65
Query: 414 KKLLPKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNP 578
+ + +KR DIF SKL C + + + A ++L L LDY+DLYL+H P
Sbjct: 66 RSKIADGSVKREDIFYTSKLW-CTFFQPQMVQPALESSLKKLQLDYVDLYLLHFP 119
>AB032163-1|BAA92893.1| 323|Homo sapiens dihydrodiol dehydrogenase
4 protein.
Length = 323
Score = 70.5 bits (165), Expect = 1e-11
Identities = 40/115 (34%), Positives = 61/115 (53%), Gaps = 2/115 (1%)
Frame = +3
Query: 240 QQFTLNNGVEMPAIGLDTFKMGHF--YTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAF 413
Q+ LN+G MP +G T+ ++ A++AG+R D+A LY NE + A
Sbjct: 6 QRVELNDGHFMPVLGFGTYAPPEVPRNRAVEVTKLAIEAGFRHIDSAYLYNNEEQVGLAI 65
Query: 414 KKLLPKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNP 578
+ + +KR DIF SKL C + + + A ++L L LDY+DLYL+H P
Sbjct: 66 RSKIADGSVKREDIFYTSKLW-CTFFQPQMVQPALESSLKKLQLDYVDLYLLHFP 119
>AB031085-1|BAA92885.1| 323|Homo sapiens dihydrodiol dehydrogenase
4 protein.
Length = 323
Score = 70.5 bits (165), Expect = 1e-11
Identities = 40/115 (34%), Positives = 61/115 (53%), Gaps = 2/115 (1%)
Frame = +3
Query: 240 QQFTLNNGVEMPAIGLDTFKMGHF--YTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAF 413
Q+ LN+G MP +G T+ ++ A++AG+R D+A LY NE + A
Sbjct: 6 QRVELNDGHFMPVLGFGTYAPPEVPRNRAVEVTKLAIEAGFRHIDSAYLYNNEEQVGLAI 65
Query: 414 KKLLPKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNP 578
+ + +KR DIF SKL C + + + A ++L L LDY+DLYL+H P
Sbjct: 66 RSKIADGSVKREDIFYTSKLW-CTFFQPQMVQPALESSLKKLQLDYVDLYLLHFP 119
>AL355480-2|CAI22458.1| 147|Homo sapiens aldo-keto reductase family
1, member A1 (aldehydela) protein.
Length = 147
Score = 68.9 bits (161), Expect = 5e-11
Identities = 45/110 (40%), Positives = 62/110 (56%), Gaps = 1/110 (0%)
Frame = +3
Query: 252 LNNGVEMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKK-LLP 428
L+ G +MP IGL T+K V V AL GYR D AA+YGNE + A K+ + P
Sbjct: 8 LHTGQKMPLIGLGTWK-SEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALKEDVGP 66
Query: 429 KYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNP 578
+ R ++F+ SKL + V E A TL++L L+Y+DLYL+H P
Sbjct: 67 GKAVPREELFVTSKLWNTKHHPEDV-EPALRKTLADLQLEYLDLYLMHWP 115
>U05598-1|AAA20937.1| 323|Homo sapiens dihydrodiol dehydrogenase
protein.
Length = 323
Score = 68.5 bits (160), Expect = 6e-11
Identities = 44/122 (36%), Positives = 61/122 (50%), Gaps = 2/122 (1%)
Frame = +3
Query: 219 DFKYILPQQFTLNNGVEMPAIGLDTFKMGHF--YTVLQTVDDALKAGYRMFDTAALYGNE 392
D KY Q LN+G MP +G T+ L+ V A++AG+ D+A +Y NE
Sbjct: 2 DSKY---QCVKLNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNE 58
Query: 393 VYLNFAFKKLLPKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVH 572
+ A + + +KR DIF SKL N + A +L NL LDY+DLYL+H
Sbjct: 59 EQVGLAIRSKIADGSVKREDIFYTSKLW-SNSHRPELVRPALERSLKNLQLDYVDLYLIH 117
Query: 573 NP 578
P
Sbjct: 118 FP 119
>S68330-1|AAD14013.1| 323|Homo sapiens chlordecone reductase
homolog protein.
Length = 323
Score = 68.5 bits (160), Expect = 6e-11
Identities = 44/122 (36%), Positives = 61/122 (50%), Gaps = 2/122 (1%)
Frame = +3
Query: 219 DFKYILPQQFTLNNGVEMPAIGLDTFKMGHF--YTVLQTVDDALKAGYRMFDTAALYGNE 392
D KY Q LN+G MP +G T+ L+ V A++AG+ D+A +Y NE
Sbjct: 2 DSKY---QCVKLNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNE 58
Query: 393 VYLNFAFKKLLPKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVH 572
+ A + + +KR DIF SKL N + A +L NL LDY+DLYL+H
Sbjct: 59 EQVGLAIRSKIADGSVKREDIFYTSKLW-SNSHRPELVRPALERSLKNLQLDYVDLYLIH 117
Query: 573 NP 578
P
Sbjct: 118 FP 119
>L32592-1|AAB38486.1| 323|Homo sapiens dihydrodiol
dehydrogenase/bile acid-binding protein protein.
Length = 323
Score = 68.5 bits (160), Expect = 6e-11
Identities = 45/122 (36%), Positives = 60/122 (49%), Gaps = 2/122 (1%)
Frame = +3
Query: 219 DFKYILPQQFTLNNGVEMPAIGLDTFKMGHF--YTVLQTVDDALKAGYRMFDTAALYGNE 392
D KY Q LN+G MP +G T+ L+ V A++AGY D+A +Y NE
Sbjct: 2 DSKY---QCVKLNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGYHHIDSAHVYNNE 58
Query: 393 VYLNFAFKKLLPKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVH 572
+ A + + +KR DIF SKL N + A +L NL LDY DLYL+H
Sbjct: 59 EQVGLAIRSKIADGSVKREDIFYTSKLW-SNSHRPELVRPALERSLKNLQLDYADLYLIH 117
Query: 573 NP 578
P
Sbjct: 118 FP 119
>BT006653-1|AAP35299.1| 323|Homo sapiens aldo-keto reductase family
1, member C2 (dihydrodiol dehydrogenase 2; bile acid
protein.
Length = 323
Score = 68.5 bits (160), Expect = 6e-11
Identities = 44/122 (36%), Positives = 61/122 (50%), Gaps = 2/122 (1%)
Frame = +3
Query: 219 DFKYILPQQFTLNNGVEMPAIGLDTFKMGHF--YTVLQTVDDALKAGYRMFDTAALYGNE 392
D KY Q LN+G MP +G T+ L+ V A++AG+ D+A +Y NE
Sbjct: 2 DSKY---QCVKLNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNE 58
Query: 393 VYLNFAFKKLLPKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVH 572
+ A + + +KR DIF SKL N + A +L NL LDY+DLYL+H
Sbjct: 59 EQVGLAIRSKIADGSVKREDIFYTSKLW-SNSHRPELVRPALERSLKNLQLDYVDLYLIH 117
Query: 573 NP 578
P
Sbjct: 118 FP 119
>BC063574-1|AAH63574.1| 323|Homo sapiens aldo-keto reductase family
1, member C2 (dihydrodiol dehydrogenase 2; bile acid
protein.
Length = 323
Score = 68.5 bits (160), Expect = 6e-11
Identities = 44/122 (36%), Positives = 61/122 (50%), Gaps = 2/122 (1%)
Frame = +3
Query: 219 DFKYILPQQFTLNNGVEMPAIGLDTFKMGHF--YTVLQTVDDALKAGYRMFDTAALYGNE 392
D KY Q LN+G MP +G T+ L+ V A++AG+ D+A +Y NE
Sbjct: 2 DSKY---QCVKLNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNE 58
Query: 393 VYLNFAFKKLLPKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVH 572
+ A + + +KR DIF SKL N + A +L NL LDY+DLYL+H
Sbjct: 59 EQVGLAIRSKIADGSVKREDIFYTSKLW-SNSHRPELVRPALERSLKNLQLDYVDLYLIH 117
Query: 573 NP 578
P
Sbjct: 118 FP 119
>BC007024-1|AAH07024.1| 323|Homo sapiens aldo-keto reductase family
1, member C2 (dihydrodiol dehydrogenase 2; bile acid
protein.
Length = 323
Score = 68.5 bits (160), Expect = 6e-11
Identities = 44/122 (36%), Positives = 61/122 (50%), Gaps = 2/122 (1%)
Frame = +3
Query: 219 DFKYILPQQFTLNNGVEMPAIGLDTFKMGHF--YTVLQTVDDALKAGYRMFDTAALYGNE 392
D KY Q LN+G MP +G T+ L+ V A++AG+ D+A +Y NE
Sbjct: 2 DSKY---QCVKLNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNE 58
Query: 393 VYLNFAFKKLLPKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVH 572
+ A + + +KR DIF SKL N + A +L NL LDY+DLYL+H
Sbjct: 59 EQVGLAIRSKIADGSVKREDIFYTSKLW-SNSHRPELVRPALERSLKNLQLDYVDLYLIH 117
Query: 573 NP 578
P
Sbjct: 118 FP 119
>AL713867-1|CAI16408.1| 323|Homo sapiens aldo-keto reductase family
1, member C2 (dihydrodiol dehydrogenase 2; bile acid
protein.
Length = 323
Score = 68.5 bits (160), Expect = 6e-11
Identities = 44/122 (36%), Positives = 61/122 (50%), Gaps = 2/122 (1%)
Frame = +3
Query: 219 DFKYILPQQFTLNNGVEMPAIGLDTFKMGHF--YTVLQTVDDALKAGYRMFDTAALYGNE 392
D KY Q LN+G MP +G T+ L+ V A++AG+ D+A +Y NE
Sbjct: 2 DSKY---QCVKLNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNE 58
Query: 393 VYLNFAFKKLLPKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVH 572
+ A + + +KR DIF SKL N + A +L NL LDY+DLYL+H
Sbjct: 59 EQVGLAIRSKIADGSVKREDIFYTSKLW-SNSHRPELVRPALERSLKNLQLDYVDLYLIH 117
Query: 573 NP 578
P
Sbjct: 118 FP 119
>AL391427-1|CAI14726.1| 323|Homo sapiens aldo-keto reductase family
1, member C2 (dihydrodiol dehydrogenase 2; bile acid
protein.
Length = 323
Score = 68.5 bits (160), Expect = 6e-11
Identities = 44/122 (36%), Positives = 61/122 (50%), Gaps = 2/122 (1%)
Frame = +3
Query: 219 DFKYILPQQFTLNNGVEMPAIGLDTFKMGHF--YTVLQTVDDALKAGYRMFDTAALYGNE 392
D KY Q LN+G MP +G T+ L+ V A++AG+ D+A +Y NE
Sbjct: 2 DSKY---QCVKLNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNE 58
Query: 393 VYLNFAFKKLLPKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVH 572
+ A + + +KR DIF SKL N + A +L NL LDY+DLYL+H
Sbjct: 59 EQVGLAIRSKIADGSVKREDIFYTSKLW-SNSHRPELVRPALERSLKNLQLDYVDLYLIH 117
Query: 573 NP 578
P
Sbjct: 118 FP 119
>AB209017-1|BAD92254.1| 286|Homo sapiens aldo-keto reductase family
1, member C2 variant protein.
Length = 286
Score = 68.5 bits (160), Expect = 6e-11
Identities = 44/122 (36%), Positives = 61/122 (50%), Gaps = 2/122 (1%)
Frame = +3
Query: 219 DFKYILPQQFTLNNGVEMPAIGLDTFKMGHF--YTVLQTVDDALKAGYRMFDTAALYGNE 392
D KY Q LN+G MP +G T+ L+ V A++AG+ D+A +Y NE
Sbjct: 15 DSKY---QCVKLNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNE 71
Query: 393 VYLNFAFKKLLPKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVH 572
+ A + + +KR DIF SKL N + A +L NL LDY+DLYL+H
Sbjct: 72 EQVGLAIRSKIADGSVKREDIFYTSKLW-SNSHRPELVRPALERSLKNLQLDYVDLYLIH 130
Query: 573 NP 578
P
Sbjct: 131 FP 132
>AB032153-1|BAA92891.1| 323|Homo sapiens bile acid-binding protein
protein.
Length = 323
Score = 68.5 bits (160), Expect = 6e-11
Identities = 44/122 (36%), Positives = 61/122 (50%), Gaps = 2/122 (1%)
Frame = +3
Query: 219 DFKYILPQQFTLNNGVEMPAIGLDTFKMGHF--YTVLQTVDDALKAGYRMFDTAALYGNE 392
D KY Q LN+G MP +G T+ L+ V A++AG+ D+A +Y NE
Sbjct: 2 DSKY---QCVKLNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNE 58
Query: 393 VYLNFAFKKLLPKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVH 572
+ A + + +KR DIF SKL N + A +L NL LDY+DLYL+H
Sbjct: 59 EQVGLAIRSKIADGSVKREDIFYTSKLW-SNSHRPELVRPALERSLKNLQLDYVDLYLIH 117
Query: 573 NP 578
P
Sbjct: 118 FP 119
>AB031084-1|BAA92884.1| 323|Homo sapiens bile acid-binding protein
protein.
Length = 323
Score = 68.5 bits (160), Expect = 6e-11
Identities = 44/122 (36%), Positives = 61/122 (50%), Gaps = 2/122 (1%)
Frame = +3
Query: 219 DFKYILPQQFTLNNGVEMPAIGLDTFKMGHF--YTVLQTVDDALKAGYRMFDTAALYGNE 392
D KY Q LN+G MP +G T+ L+ V A++AG+ D+A +Y NE
Sbjct: 2 DSKY---QCVKLNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNE 58
Query: 393 VYLNFAFKKLLPKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVH 572
+ A + + +KR DIF SKL N + A +L NL LDY+DLYL+H
Sbjct: 59 EQVGLAIRSKIADGSVKREDIFYTSKLW-SNSHRPELVRPALERSLKNLQLDYVDLYLIH 117
Query: 573 NP 578
P
Sbjct: 118 FP 119
>AB021654-1|BAA36169.1| 323|Homo sapiens DD2/bile acid-binding
protein/AKR1C2/3alpha-hydroxysteroid dehydrogenase type
3 protein.
Length = 323
Score = 68.5 bits (160), Expect = 6e-11
Identities = 44/122 (36%), Positives = 61/122 (50%), Gaps = 2/122 (1%)
Frame = +3
Query: 219 DFKYILPQQFTLNNGVEMPAIGLDTFKMGHF--YTVLQTVDDALKAGYRMFDTAALYGNE 392
D KY Q LN+G MP +G T+ L+ V A++AG+ D+A +Y NE
Sbjct: 2 DSKY---QCVKLNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNE 58
Query: 393 VYLNFAFKKLLPKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVH 572
+ A + + +KR DIF SKL N + A +L NL LDY+DLYL+H
Sbjct: 59 EQVGLAIRSKIADGSVKREDIFYTSKLW-SNSHRPELVRPALERSLKNLQLDYVDLYLIH 117
Query: 573 NP 578
P
Sbjct: 118 FP 119
>D17793-1|BAA04619.2| 325|Homo sapiens KIAA0119 protein.
Length = 325
Score = 68.1 bits (159), Expect = 8e-11
Identities = 39/111 (35%), Positives = 57/111 (51%), Gaps = 2/111 (1%)
Frame = +3
Query: 252 LNNGVEMPAIGLDTFKMGHF--YTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLL 425
LN+G MP +G T+ L+ A++AG+R D+A LY NE + A + +
Sbjct: 12 LNDGHFMPVLGFGTYAPPEVPRSKALEVTKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKI 71
Query: 426 PKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNP 578
+KR DIF SKL + + A N+L LDY+DLYL+H+P
Sbjct: 72 ADGSVKREDIFYTSKLW-STFHRPELVRPALENSLKKAQLDYVDLYLIHSP 121
>BT007286-1|AAP35950.1| 323|Homo sapiens aldo-keto reductase family
1, member C3 (3-alpha hydroxysteroid dehydrogenase,
protein.
Length = 323
Score = 68.1 bits (159), Expect = 8e-11
Identities = 39/111 (35%), Positives = 57/111 (51%), Gaps = 2/111 (1%)
Frame = +3
Query: 252 LNNGVEMPAIGLDTFKMGHF--YTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLL 425
LN+G MP +G T+ L+ A++AG+R D+A LY NE + A + +
Sbjct: 10 LNDGHFMPVLGFGTYAPPEVPRSKALEVTKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKI 69
Query: 426 PKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNP 578
+KR DIF SKL + + A N+L LDY+DLYL+H+P
Sbjct: 70 ADGSVKREDIFYTSKLW-STFHRPELVRPALENSLKKAQLDYVDLYLIHSP 119
>BC019230-1|AAH19230.1| 323|Homo sapiens aldo-keto reductase family
1, member C3 (3-alpha hydroxysteroid dehydrogenase,
protein.
Length = 323
Score = 68.1 bits (159), Expect = 8e-11
Identities = 39/111 (35%), Positives = 57/111 (51%), Gaps = 2/111 (1%)
Frame = +3
Query: 252 LNNGVEMPAIGLDTFKMGHF--YTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLL 425
LN+G MP +G T+ L+ A++AG+R D+A LY NE + A + +
Sbjct: 10 LNDGHFMPVLGFGTYAPPEVPRSKALEVTKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKI 69
Query: 426 PKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNP 578
+KR DIF SKL + + A N+L LDY+DLYL+H+P
Sbjct: 70 ADGSVKREDIFYTSKLW-STFHRPELVRPALENSLKKAQLDYVDLYLIHSP 119
>BC001479-1|AAH01479.1| 323|Homo sapiens aldo-keto reductase family
1, member C3 (3-alpha hydroxysteroid dehydrogenase,
protein.
Length = 323
Score = 68.1 bits (159), Expect = 8e-11
Identities = 39/111 (35%), Positives = 57/111 (51%), Gaps = 2/111 (1%)
Frame = +3
Query: 252 LNNGVEMPAIGLDTFKMGHF--YTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLL 425
LN+G MP +G T+ L+ A++AG+R D+A LY NE + A + +
Sbjct: 10 LNDGHFMPVLGFGTYAPPEVPRSKALEVTKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKI 69
Query: 426 PKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNP 578
+KR DIF SKL + + A N+L LDY+DLYL+H+P
Sbjct: 70 ADGSVKREDIFYTSKLW-STFHRPELVRPALENSLKKAQLDYVDLYLIHSP 119
>AL391427-4|CAI14729.1| 323|Homo sapiens aldo-keto reductase family
1, member C3 (3-alpha hydroxysteroid dehydrogenase,
protein.
Length = 323
Score = 68.1 bits (159), Expect = 8e-11
Identities = 39/111 (35%), Positives = 57/111 (51%), Gaps = 2/111 (1%)
Frame = +3
Query: 252 LNNGVEMPAIGLDTFKMGHF--YTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLL 425
LN+G MP +G T+ L+ A++AG+R D+A LY NE + A + +
Sbjct: 10 LNDGHFMPVLGFGTYAPPEVPRSKALEVTKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKI 69
Query: 426 PKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNP 578
+KR DIF SKL + + A N+L LDY+DLYL+H+P
Sbjct: 70 ADGSVKREDIFYTSKLW-STFHRPELVRPALENSLKKAQLDYVDLYLIHSP 119
>AF149416-1|AAF07272.2| 323|Homo sapiens 3-alpha hydroxysteroid
dehydrogenase type IIb protein.
Length = 323
Score = 68.1 bits (159), Expect = 8e-11
Identities = 40/111 (36%), Positives = 58/111 (52%), Gaps = 2/111 (1%)
Frame = +3
Query: 252 LNNGVEMPAIGLDTFKMGHF--YTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLL 425
LN+G MP +G T+ L+ A++AG+R D+A LY NE + A + +
Sbjct: 10 LNDGHFMPVLGFGTYAPPEVPRSKALEVSKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKI 69
Query: 426 PKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNP 578
+KR DIF SKL ++ V A N+L LDY+DLYL+H+P
Sbjct: 70 ADGSVKREDIFYTSKLWSTSHRPELV-RPALENSLKKAQLDYVDLYLIHSP 119
>AB032157-1|BAA92892.1| 323|Homo sapiens prostaglandin F synthase
protein.
Length = 323
Score = 68.1 bits (159), Expect = 8e-11
Identities = 39/111 (35%), Positives = 57/111 (51%), Gaps = 2/111 (1%)
Frame = +3
Query: 252 LNNGVEMPAIGLDTFKMGHF--YTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLL 425
LN+G MP +G T+ L+ A++AG+R D+A LY NE + A + +
Sbjct: 10 LNDGHFMPVLGFGTYAPPEVPRSKALEVTKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKI 69
Query: 426 PKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNP 578
+KR DIF SKL + + A N+L LDY+DLYL+H+P
Sbjct: 70 ADGSVKREDIFYTSKLW-STFHRPELVRPALENSLKKAQLDYVDLYLIHSP 119
>AB018580-1|BAA88488.1| 323|Homo sapiens hluPGFS protein.
Length = 323
Score = 68.1 bits (159), Expect = 8e-11
Identities = 39/111 (35%), Positives = 57/111 (51%), Gaps = 2/111 (1%)
Frame = +3
Query: 252 LNNGVEMPAIGLDTFKMGHF--YTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLL 425
LN+G MP +G T+ L+ A++AG+R D+A LY NE + A + +
Sbjct: 10 LNDGHFMPVLGFGTYAPPEVPRSKALEVTKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKI 69
Query: 426 PKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNP 578
+KR DIF SKL + + A N+L LDY+DLYL+H+P
Sbjct: 70 ADGSVKREDIFYTSKLW-STFHRPELVRPALENSLKKAQLDYVDLYLIHSP 119
>S68288-1|AAD14011.1| 323|Homo sapiens chlordecone reductase
homolog protein.
Length = 323
Score = 66.5 bits (155), Expect = 2e-10
Identities = 38/111 (34%), Positives = 57/111 (51%), Gaps = 2/111 (1%)
Frame = +3
Query: 252 LNNGVEMPAIGLDTFKMGHF--YTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLL 425
LN+G MP +G T+ L+ A++AG+R D+A LY NE + A + +
Sbjct: 10 LNDGHFMPVLGFGTYAPPEVPRSKALEVTKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKI 69
Query: 426 PKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNP 578
++R DIF SKL + + A N+L LDY+DLYL+H+P
Sbjct: 70 ADGSVEREDIFYTSKLW-STFHRPELVRPALENSLKKAQLDYVDLYLIHSP 119
>D26124-1|BAA05121.1| 306|Homo sapiens dihydrodiol dehydrogenase
isoform DD1 protein.
Length = 306
Score = 66.5 bits (155), Expect = 2e-10
Identities = 35/86 (40%), Positives = 48/86 (55%)
Frame = +3
Query: 321 LQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPKYKLKRGDIFIISKLLPCNYGGGA 500
L+ A++AG+R D+A LY NE + A + + +KR DIF SKL CN
Sbjct: 18 LEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVKREDIFYTSKLW-CNSHRPE 76
Query: 501 VTERAFHNTLSNLGLDYIDLYLVHNP 578
+ A +L NL LDY+DLYL+H P
Sbjct: 77 LVRPALERSLKNLQLDYVDLYLIHFP 102
>L43839-1|AAB41916.1| 323|Homo sapiens 3-alpha-hydroxysteroid
dehydrogenase protein.
Length = 323
Score = 65.7 bits (153), Expect = 4e-10
Identities = 38/111 (34%), Positives = 56/111 (50%), Gaps = 2/111 (1%)
Frame = +3
Query: 252 LNNGVEMPAIGLDTFKMGHF--YTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLL 425
LN+G MP +G T+ L+ A++AG+R D+A LY NE + A + +
Sbjct: 10 LNDGHFMPVLGFGTYAPPEVPRSKALEVTKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKI 69
Query: 426 PKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNP 578
+ R DIF SKL + + A N+L LDY+DLYL+H+P
Sbjct: 70 ADGSVMREDIFYTSKLW-STFHRPELVRPALENSLKKAQLDYVDLYLIHSP 119
>BC002862-1|AAH02862.1| 307|Homo sapiens AKR1CL2 protein protein.
Length = 307
Score = 65.7 bits (153), Expect = 4e-10
Identities = 38/108 (35%), Positives = 61/108 (56%)
Frame = +3
Query: 267 EMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPKYKLKR 446
++PA+GL ++K V + V +A+ AGYR FD A Y NE + + + + ++R
Sbjct: 3 DIPAVGLSSWKASPG-KVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEGAVRR 61
Query: 447 GDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYK 590
D+FI +KL C ++ E A +L L L+Y+DLYL+H P +K
Sbjct: 62 EDLFIATKLW-CTCHKKSLVETACRKSLKALKLNYLDLYLIHWPMGFK 108
>AF263242-1|AAK58523.1| 320|Homo sapiens aldo-keto reductase
loopADR protein.
Length = 320
Score = 65.7 bits (153), Expect = 4e-10
Identities = 38/108 (35%), Positives = 61/108 (56%)
Frame = +3
Query: 267 EMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPKYKLKR 446
++PA+GL ++K V + V +A+ AGYR FD A Y NE + + + + ++R
Sbjct: 3 DIPAVGLSSWKASPG-KVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEGAVRR 61
Query: 447 GDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYK 590
D+FI +KL C ++ E A +L L L+Y+DLYL+H P +K
Sbjct: 62 EDLFIATKLW-CTCHKKSLVETACRKSLKALKLNYLDLYLIHWPMGFK 108
>AB055603-1|BAC54568.1| 307|Homo sapiens aldo-keto reductase
related protein 4 protein.
Length = 307
Score = 65.7 bits (153), Expect = 4e-10
Identities = 38/108 (35%), Positives = 61/108 (56%)
Frame = +3
Query: 267 EMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPKYKLKR 446
++PA+GL ++K V + V +A+ AGYR FD A Y NE + + + + ++R
Sbjct: 3 DIPAVGLSSWKASPG-KVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEGAVRR 61
Query: 447 GDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYK 590
D+FI +KL C ++ E A +L L L+Y+DLYL+H P +K
Sbjct: 62 EDLFIATKLW-CTCHKKSLVETACRKSLKALKLNYLDLYLIHWPMGFK 108
>AB040822-1|BAC54567.1| 222|Homo sapiens aldo-keto reductase
related protein 3 protein.
Length = 222
Score = 65.7 bits (153), Expect = 4e-10
Identities = 38/108 (35%), Positives = 61/108 (56%)
Frame = +3
Query: 267 EMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPKYKLKR 446
++PA+GL ++K V + V +A+ AGYR FD A Y NE + + + + ++R
Sbjct: 3 DIPAVGLSSWKASPG-KVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEGAVRR 61
Query: 447 GDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYK 590
D+FI +KL C ++ E A +L L L+Y+DLYL+H P +K
Sbjct: 62 EDLFIATKLW-CTCHKKSLVETACRKSLKALKLNYLDLYLIHWPMGFK 108
>AB040821-1|BAC54566.1| 263|Homo sapiens aldo-keto reductase
related protein 2 protein.
Length = 263
Score = 65.7 bits (153), Expect = 4e-10
Identities = 38/108 (35%), Positives = 61/108 (56%)
Frame = +3
Query: 267 EMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPKYKLKR 446
++PA+GL ++K V + V +A+ AGYR FD A Y NE + + + + ++R
Sbjct: 3 DIPAVGLSSWKASPG-KVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEGAVRR 61
Query: 447 GDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYK 590
D+FI +KL C ++ E A +L L L+Y+DLYL+H P +K
Sbjct: 62 EDLFIATKLW-CTCHKKSLVETACRKSLKALKLNYLDLYLIHWPMGFK 108
>AB040820-1|BAC54565.1| 250|Homo sapiens aldo-keto reductase
related protein 1 protein.
Length = 250
Score = 65.7 bits (153), Expect = 4e-10
Identities = 38/108 (35%), Positives = 61/108 (56%)
Frame = +3
Query: 267 EMPAIGLDTFKMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPKYKLKR 446
++PA+GL ++K V + V +A+ AGYR FD A Y NE + + + + ++R
Sbjct: 3 DIPAVGLSSWKASPG-KVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEGAVRR 61
Query: 447 GDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYK 590
D+FI +KL C ++ E A +L L L+Y+DLYL+H P +K
Sbjct: 62 EDLFIATKLW-CTCHKKSLVETACRKSLKALKLNYLDLYLIHWPMGFK 108
>M33375-1|AAA35658.1| 308|Homo sapiens protein ( Human chlordecone
reductase mRNA, complete cds. ).
Length = 308
Score = 64.5 bits (150), Expect = 1e-09
Identities = 36/105 (34%), Positives = 55/105 (52%), Gaps = 2/105 (1%)
Frame = +3
Query: 270 MPAIGLDTFKMGHF--YTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLLPKYKLK 443
MP +G T+ ++ A++AG+R D+A LY NE + A + + +K
Sbjct: 1 MPVLGFGTYAPPEVPRNRAVEVTKLAIEAGFRHIDSAYLYNNEEQVGLAIRSKIADGSVK 60
Query: 444 RGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNP 578
R DIF SKL C + + + A ++L L LDY+DLYL+H P
Sbjct: 61 REDIFYTSKLW-CTFFQPQMVQPALESSLKKLQLDYVDLYLLHFP 104
>Z28339-1|CAA82193.1| 326|Homo sapiens delta 4-3-oxosteroid 5
beta-reductase protein.
Length = 326
Score = 58.8 bits (136), Expect = 5e-08
Identities = 48/161 (29%), Positives = 75/161 (46%), Gaps = 12/161 (7%)
Frame = +3
Query: 252 LNNGVEMPAIGLDTF---KMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKL 422
L++G +P IGL T+ K +V A+ GYR D A +Y NE + A ++
Sbjct: 12 LSDGNSIPIIGLGTYSEPKSTPKGACATSVKVAIDTGYRHIDGAYIYQNEHEVGEAIREK 71
Query: 423 LPKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLDFE 602
+ + K++R DIF KL N+ V TL L LDY+DLY++ P +K E
Sbjct: 72 IAEGKVRREDIFYCGKLWATNHVPEMV-RPTLERTLRVLQLDYVDLYIIEVPMAFKPGDE 130
Query: 603 ----NRNSSRIRKQ-----TWATLVDLYHDHKIRALGVSNY 698
+ N + + TW + +++LGVSN+
Sbjct: 131 IYPRDENGKWLYHKSNLCATWEAMEACKDAGLVKSLGVSNF 171
>BC130627-1|AAI30628.1| 326|Homo sapiens aldo-keto reductase family
1, member D1 (delta 4-3-ketosteroid-5-beta-reductase
protein.
Length = 326
Score = 58.8 bits (136), Expect = 5e-08
Identities = 48/161 (29%), Positives = 75/161 (46%), Gaps = 12/161 (7%)
Frame = +3
Query: 252 LNNGVEMPAIGLDTF---KMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKL 422
L++G +P IGL T+ K +V A+ GYR D A +Y NE + A ++
Sbjct: 12 LSDGNSIPIIGLGTYSEPKSTPKGACATSVKVAIDTGYRHIDGAYIYQNEHEVGEAIREK 71
Query: 423 LPKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLDFE 602
+ + K++R DIF KL N+ V TL L LDY+DLY++ P +K E
Sbjct: 72 IAEGKVRREDIFYCGKLWATNHVPEMV-RPTLERTLRVLQLDYVDLYIIEVPMAFKPGDE 130
Query: 603 ----NRNSSRIRKQ-----TWATLVDLYHDHKIRALGVSNY 698
+ N + + TW + +++LGVSN+
Sbjct: 131 IYPRDENGKWLYHKSNLCATWEAMEACKDAGLVKSLGVSNF 171
>BC130625-1|AAI30626.1| 326|Homo sapiens aldo-keto reductase family
1, member D1 (delta 4-3-ketosteroid-5-beta-reductase
protein.
Length = 326
Score = 58.8 bits (136), Expect = 5e-08
Identities = 48/161 (29%), Positives = 75/161 (46%), Gaps = 12/161 (7%)
Frame = +3
Query: 252 LNNGVEMPAIGLDTF---KMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKL 422
L++G +P IGL T+ K +V A+ GYR D A +Y NE + A ++
Sbjct: 12 LSDGNSIPIIGLGTYSEPKSTPKGACATSVKVAIDTGYRHIDGAYIYQNEHEVGEAIREK 71
Query: 423 LPKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLDFE 602
+ + K++R DIF KL N+ V TL L LDY+DLY++ P +K E
Sbjct: 72 IAEGKVRREDIFYCGKLWATNHVPEMV-RPTLERTLRVLQLDYVDLYIIEVPMAFKPGDE 130
Query: 603 ----NRNSSRIRKQ-----TWATLVDLYHDHKIRALGVSNY 698
+ N + + TW + +++LGVSN+
Sbjct: 131 IYPRDENGKWLYHKSNLCATWEAMEACKDAGLVKSLGVSNF 171
>AF283659-1|AAG39381.1| 326|Homo sapiens 5-beta steroid reductase
protein.
Length = 326
Score = 58.8 bits (136), Expect = 5e-08
Identities = 48/161 (29%), Positives = 75/161 (46%), Gaps = 12/161 (7%)
Frame = +3
Query: 252 LNNGVEMPAIGLDTF---KMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKL 422
L++G +P IGL T+ K +V A+ GYR D A +Y NE + A ++
Sbjct: 12 LSDGNSIPIIGLGTYSEPKSTPKGACATSVKVAIDTGYRHIDGAYIYQNEHEVGEAIREK 71
Query: 423 LPKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNPGIYKLDFE 602
+ + K++R DIF KL N+ V TL L LDY+DLY++ P +K E
Sbjct: 72 IAEGKVRREDIFYCGKLWATNHVPEMV-RPTLERTLRVLQLDYVDLYIIEVPMAFKPGDE 130
Query: 603 ----NRNSSRIRKQ-----TWATLVDLYHDHKIRALGVSNY 698
+ N + + TW + +++LGVSN+
Sbjct: 131 IYPRDENGKWLYHKSNLCATWEAMEACKDAGLVKSLGVSNF 171
>BC101205-1|AAI01206.1| 129|Homo sapiens aldo-keto reductase family
1, member C-like 1 protein.
Length = 129
Score = 56.0 bits (129), Expect = 3e-07
Identities = 34/111 (30%), Positives = 53/111 (47%), Gaps = 2/111 (1%)
Frame = +3
Query: 252 LNNGVEMPAIGLDTFKMGHF--YTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLL 425
LN+G MP +G T+ H + A+ G+R D+A LY NE + A + +
Sbjct: 13 LNDGPFMPVLGFGTYAPDHTPKSQAAEATKVAIDVGFRHIDSAYLYQNEEEVGQAIWEKI 72
Query: 426 PKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNP 578
+KR +IF KL + + A +L LG DY+DL+++H P
Sbjct: 73 ADGTVKREEIFYTIKLW-ATFFRAELVHPALERSLKKLGPDYVDLFIIHVP 122
>BC101204-1|AAI01205.1| 129|Homo sapiens aldo-keto reductase family
1, member C-like 1 protein.
Length = 129
Score = 56.0 bits (129), Expect = 3e-07
Identities = 34/111 (30%), Positives = 53/111 (47%), Gaps = 2/111 (1%)
Frame = +3
Query: 252 LNNGVEMPAIGLDTFKMGHF--YTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLL 425
LN+G MP +G T+ H + A+ G+R D+A LY NE + A + +
Sbjct: 13 LNDGPFMPVLGFGTYAPDHTPKSQAAEATKVAIDVGFRHIDSAYLYQNEEEVGQAIWEKI 72
Query: 426 PKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNP 578
+KR +IF KL + + A +L LG DY+DL+++H P
Sbjct: 73 ADGTVKREEIFYTIKLW-ATFFRAELVHPALERSLKKLGPDYVDLFIIHVP 122
>AL391427-2|CAI14727.1| 302|Homo sapiens aldo-keto reductase family
1, member C-like 1 protein.
Length = 302
Score = 56.0 bits (129), Expect = 3e-07
Identities = 34/111 (30%), Positives = 53/111 (47%), Gaps = 2/111 (1%)
Frame = +3
Query: 252 LNNGVEMPAIGLDTFKMGHF--YTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLL 425
LN+G MP +G T+ H + A+ G+R D+A LY NE + A + +
Sbjct: 13 LNDGPFMPVLGFGTYAPDHTPKSQAAEATKVAIDVGFRHIDSAYLYQNEEEVGQAIWEKI 72
Query: 426 PKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNP 578
+KR +IF KL + + A +L LG DY+DL+++H P
Sbjct: 73 ADGTVKREEIFYTIKLW-ATFFRAELVHPALERSLKKLGPDYVDLFIIHVP 122
>AL355303-1|CAI14201.1| 302|Homo sapiens aldo-keto reductase family
1, member C-like 1 protein.
Length = 302
Score = 56.0 bits (129), Expect = 3e-07
Identities = 34/111 (30%), Positives = 53/111 (47%), Gaps = 2/111 (1%)
Frame = +3
Query: 252 LNNGVEMPAIGLDTFKMGHF--YTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLL 425
LN+G MP +G T+ H + A+ G+R D+A LY NE + A + +
Sbjct: 13 LNDGPFMPVLGFGTYAPDHTPKSQAAEATKVAIDVGFRHIDSAYLYQNEEEVGQAIWEKI 72
Query: 426 PKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNP 578
+KR +IF KL + + A +L LG DY+DL+++H P
Sbjct: 73 ADGTVKREEIFYTIKLW-ATFFRAELVHPALERSLKKLGPDYVDLFIIHVP 122
>AK131335-1|BAD18494.1| 129|Homo sapiens protein ( Homo sapiens
cDNA FLJ16347 fis, clone TESTI2036288, moderately
similar to PROSTAGLANDIN-F SYNTHASE 1 (EC 1.1.1.188). ).
Length = 129
Score = 56.0 bits (129), Expect = 3e-07
Identities = 34/111 (30%), Positives = 53/111 (47%), Gaps = 2/111 (1%)
Frame = +3
Query: 252 LNNGVEMPAIGLDTFKMGHF--YTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLL 425
LN+G MP +G T+ H + A+ G+R D+A LY NE + A + +
Sbjct: 13 LNDGPFMPVLGFGTYAPDHTPKSQAAEATKVAIDVGFRHIDSAYLYQNEEEVGQAIWEKI 72
Query: 426 PKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNP 578
+KR +IF KL + + A +L LG DY+DL+++H P
Sbjct: 73 ADGTVKREEIFYTIKLW-ATFFRAELVHPALERSLKKLGPDYVDLFIIHVP 122
>AB037902-1|BAA92887.1| 130|Homo sapiens truncated aldo-keto
reductase protein.
Length = 130
Score = 54.8 bits (126), Expect = 8e-07
Identities = 36/111 (32%), Positives = 54/111 (48%), Gaps = 2/111 (1%)
Frame = +3
Query: 252 LNNGVEMPAIGLDTF--KMGHFYTVLQTVDDALKAGYRMFDTAALYGNEVYLNFAFKKLL 425
LN+G MP +G T + V + V A+ GYR D+A + NE + A +K +
Sbjct: 11 LNDGKFMPILGFGTSVARKVAMSNVEEAVQVAIDVGYRHIDSAYTHLNEEGIGQAIRKKI 70
Query: 426 PKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNP 578
+KR DIF +K+ + + +R +L L L Y+DLYL H P
Sbjct: 71 ANGTVKRKDIFYTTKVWG-TFSRPELVQRGLEMSLKKLQLSYMDLYLFHFP 120
>AL713867-3|CAI16410.1| 247|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 247
Score = 45.6 bits (103), Expect = 5e-04
Identities = 24/60 (40%), Positives = 32/60 (53%)
Frame = +3
Query: 399 LNFAFKKLLPKYKLKRGDIFIISKLLPCNYGGGAVTERAFHNTLSNLGLDYIDLYLVHNP 578
+ A + + +KR DIF SKL CN + A +L NL LDY+DLYL+H P
Sbjct: 27 VGLAIRSKIADGSVKREDIFYTSKLW-CNSHRPELVRPALERSLKNLQLDYVDLYLIHFP 85
>BC015232-1|AAH15232.2| 148|Homo sapiens transmembrane protein 136
protein.
Length = 148
Score = 32.7 bits (71), Expect = 3.6
Identities = 13/31 (41%), Positives = 18/31 (58%)
Frame = +1
Query: 202 GWKTLKISNTYCHNNSHSTMEWKCLPLDWIH 294
GW +L IS +CH N H + EW C + + H
Sbjct: 37 GWLSLYIS--FCHLNKHRSYEWSCRLVTFTH 65
>AK128040-1|BAC87244.1| 245|Homo sapiens protein ( Homo sapiens
cDNA FLJ46159 fis, clone TESTI4002072. ).
Length = 245
Score = 32.7 bits (71), Expect = 3.6
Identities = 13/31 (41%), Positives = 18/31 (58%)
Frame = +1
Query: 202 GWKTLKISNTYCHNNSHSTMEWKCLPLDWIH 294
GW +L IS +CH N H + EW C + + H
Sbjct: 15 GWLSLYIS--FCHLNKHRSYEWSCRLVTFTH 43
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 190,598,534
Number of Sequences: 237096
Number of extensions: 3963653
Number of successful extensions: 7559
Number of sequences better than 10.0: 92
Number of HSP's better than 10.0 without gapping: 5767
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 7249
length of database: 76,859,062
effective HSP length: 93
effective length of database: 54,809,134
effective search space used: 22690981476
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
- SilkBase 1999-2023 -