Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= 030725E6_E04_e509_10.seq
(1534 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
U20938-1|AAB51366.1| 1025|Homo sapiens dihydropyrimidine dehydro... 421 e-117
U09178-1|AAA57474.1| 1025|Homo sapiens dihydropyrimidine dehydro... 421 e-117
BX908805-1|CAI15125.1| 1025|Homo sapiens dihydropyrimidine dehyd... 421 e-117
BC131777-1|AAI31778.1| 1025|Homo sapiens dihydropyrimidine dehyd... 421 e-117
AL356457-3|CAH70570.1| 1025|Homo sapiens dihydropyrimidine dehyd... 421 e-117
AB003063-1|BAA89789.1| 1025|Homo sapiens dihydropyrimidine dehyd... 421 e-117
BC131778-1|AAI31779.1| 1025|Homo sapiens dihydropyrimidine dehyd... 421 e-117
X95670-1|CAA64973.1| 55|Homo sapiens dihydropyrimidine dehydro... 98 7e-20
U57655-1|AAB07049.1| 55|Homo sapiens dihydropyrimidine dehydro... 98 7e-20
AB058717-1|BAB47443.1| 1285|Homo sapiens KIAA1814 protein protein. 35 0.91
BC064391-1|AAH64391.1| 474|Homo sapiens coiled-coil domain cont... 31 8.5
BC036757-1|AAH36757.2| 474|Homo sapiens coiled-coil domain cont... 31 8.5
>U20938-1|AAB51366.1| 1025|Homo sapiens dihydropyrimidine
dehydrogenase protein.
Length = 1025
Score = 421 bits (1038), Expect = e-117
Identities = 194/272 (71%), Positives = 225/272 (82%)
Frame = +2
Query: 92 EQGWGFAVTKTFSLDKDMVTNVSPRIVRGVTSGENYGPGQGSFLNIELISEKCEAYWCQS 271
E GWGFA+TKTFSLDKD+VTNVSPRI+RG TSG YGPGQ SFLNIELISEK AYWCQS
Sbjct: 565 EAGWGFALTKTFSLDKDIVTNVSPRIIRGTTSGPMYGPGQSSFLNIELISEKTAAYWCQS 624
Query: 272 VTELKKDFPNKVIIASIMCSYNEEDWTLLSKKAEAAGADALELNLSCPHGMGESGMGLAC 451
VTELK DFP+ ++IASIMCSYN+ DWT L+KK+E +GADALELNLSCPHGMGE GMGLAC
Sbjct: 625 VTELKADFPDNIVIASIMCSYNKNDWTELAKKSEDSGADALELNLSCPHGMGERGMGLAC 684
Query: 452 GQDPVLVKGISQWVRKAIKIPFFVKLTPNITDIVSIAVAAYEGGASGVSAINTVSGLMSI 631
GQDP LV+ I +WVR+A++IPFF KLTPN+TDIVSIA AA EGGA+GV+A NTVSGLM +
Sbjct: 685 GQDPELVRNICRWVRQAVQIPFFAKLTPNVTDIVSIARAAKEGGANGVTATNTVSGLMGL 744
Query: 632 RADGTPWPAVGREKHTTYGGLSGNATRPMGLRAVSAIGNRXXXXXXXXXXXXDSAESALQ 811
++DGTPWPAVG K TTYGG+SG A RP+ LRAV++I DSAES LQ
Sbjct: 745 KSDGTPWPAVGIAKRTTYGGVSGTAIRPIALRAVTSIARALPGFPILATGGIDSAESGLQ 804
Query: 812 FIMCGAPVVQICSAVQNQDFTVVDDYITGLKA 907
F+ GA V+Q+CSA+QNQDFTV++DY TGLKA
Sbjct: 805 FLHSGASVLQVCSAIQNQDFTVIEDYCTGLKA 836
>U09178-1|AAA57474.1| 1025|Homo sapiens dihydropyrimidine
dehydrogenase protein.
Length = 1025
Score = 421 bits (1038), Expect = e-117
Identities = 194/272 (71%), Positives = 225/272 (82%)
Frame = +2
Query: 92 EQGWGFAVTKTFSLDKDMVTNVSPRIVRGVTSGENYGPGQGSFLNIELISEKCEAYWCQS 271
E GWGFA+TKTFSLDKD+VTNVSPRI+RG TSG YGPGQ SFLNIELISEK AYWCQS
Sbjct: 565 EAGWGFALTKTFSLDKDIVTNVSPRIIRGTTSGPMYGPGQSSFLNIELISEKTAAYWCQS 624
Query: 272 VTELKKDFPNKVIIASIMCSYNEEDWTLLSKKAEAAGADALELNLSCPHGMGESGMGLAC 451
VTELK DFP+ ++IASIMCSYN+ DWT L+KK+E +GADALELNLSCPHGMGE GMGLAC
Sbjct: 625 VTELKADFPDNIVIASIMCSYNKNDWTELAKKSEDSGADALELNLSCPHGMGERGMGLAC 684
Query: 452 GQDPVLVKGISQWVRKAIKIPFFVKLTPNITDIVSIAVAAYEGGASGVSAINTVSGLMSI 631
GQDP LV+ I +WVR+A++IPFF KLTPN+TDIVSIA AA EGGA+GV+A NTVSGLM +
Sbjct: 685 GQDPELVRNICRWVRQAVQIPFFAKLTPNVTDIVSIARAAKEGGANGVTATNTVSGLMGL 744
Query: 632 RADGTPWPAVGREKHTTYGGLSGNATRPMGLRAVSAIGNRXXXXXXXXXXXXDSAESALQ 811
++DGTPWPAVG K TTYGG+SG A RP+ LRAV++I DSAES LQ
Sbjct: 745 KSDGTPWPAVGIAKRTTYGGVSGTAIRPIALRAVTSIARALPGFPILATGGIDSAESGLQ 804
Query: 812 FIMCGAPVVQICSAVQNQDFTVVDDYITGLKA 907
F+ GA V+Q+CSA+QNQDFTV++DY TGLKA
Sbjct: 805 FLHSGASVLQVCSAIQNQDFTVIEDYCTGLKA 836
>BX908805-1|CAI15125.1| 1025|Homo sapiens dihydropyrimidine
dehydrogenase protein.
Length = 1025
Score = 421 bits (1038), Expect = e-117
Identities = 194/272 (71%), Positives = 225/272 (82%)
Frame = +2
Query: 92 EQGWGFAVTKTFSLDKDMVTNVSPRIVRGVTSGENYGPGQGSFLNIELISEKCEAYWCQS 271
E GWGFA+TKTFSLDKD+VTNVSPRI+RG TSG YGPGQ SFLNIELISEK AYWCQS
Sbjct: 565 EAGWGFALTKTFSLDKDIVTNVSPRIIRGTTSGPMYGPGQSSFLNIELISEKTAAYWCQS 624
Query: 272 VTELKKDFPNKVIIASIMCSYNEEDWTLLSKKAEAAGADALELNLSCPHGMGESGMGLAC 451
VTELK DFP+ ++IASIMCSYN+ DWT L+KK+E +GADALELNLSCPHGMGE GMGLAC
Sbjct: 625 VTELKADFPDNIVIASIMCSYNKNDWTELAKKSEDSGADALELNLSCPHGMGERGMGLAC 684
Query: 452 GQDPVLVKGISQWVRKAIKIPFFVKLTPNITDIVSIAVAAYEGGASGVSAINTVSGLMSI 631
GQDP LV+ I +WVR+A++IPFF KLTPN+TDIVSIA AA EGGA+GV+A NTVSGLM +
Sbjct: 685 GQDPELVRNICRWVRQAVQIPFFAKLTPNVTDIVSIARAAKEGGANGVTATNTVSGLMGL 744
Query: 632 RADGTPWPAVGREKHTTYGGLSGNATRPMGLRAVSAIGNRXXXXXXXXXXXXDSAESALQ 811
++DGTPWPAVG K TTYGG+SG A RP+ LRAV++I DSAES LQ
Sbjct: 745 KSDGTPWPAVGIAKRTTYGGVSGTAIRPIALRAVTSIARALPGFPILATGGIDSAESGLQ 804
Query: 812 FIMCGAPVVQICSAVQNQDFTVVDDYITGLKA 907
F+ GA V+Q+CSA+QNQDFTV++DY TGLKA
Sbjct: 805 FLHSGASVLQVCSAIQNQDFTVIEDYCTGLKA 836
>BC131777-1|AAI31778.1| 1025|Homo sapiens dihydropyrimidine
dehydrogenase protein.
Length = 1025
Score = 421 bits (1038), Expect = e-117
Identities = 194/272 (71%), Positives = 225/272 (82%)
Frame = +2
Query: 92 EQGWGFAVTKTFSLDKDMVTNVSPRIVRGVTSGENYGPGQGSFLNIELISEKCEAYWCQS 271
E GWGFA+TKTFSLDKD+VTNVSPRI+RG TSG YGPGQ SFLNIELISEK AYWCQS
Sbjct: 565 EAGWGFALTKTFSLDKDIVTNVSPRIIRGTTSGPMYGPGQSSFLNIELISEKTAAYWCQS 624
Query: 272 VTELKKDFPNKVIIASIMCSYNEEDWTLLSKKAEAAGADALELNLSCPHGMGESGMGLAC 451
VTELK DFP+ ++IASIMCSYN+ DWT L+KK+E +GADALELNLSCPHGMGE GMGLAC
Sbjct: 625 VTELKADFPDNIVIASIMCSYNKNDWTELAKKSEDSGADALELNLSCPHGMGERGMGLAC 684
Query: 452 GQDPVLVKGISQWVRKAIKIPFFVKLTPNITDIVSIAVAAYEGGASGVSAINTVSGLMSI 631
GQDP LV+ I +WVR+A++IPFF KLTPN+TDIVSIA AA EGGA+GV+A NTVSGLM +
Sbjct: 685 GQDPELVRNICRWVRQAVQIPFFAKLTPNVTDIVSIARAAKEGGANGVTATNTVSGLMGL 744
Query: 632 RADGTPWPAVGREKHTTYGGLSGNATRPMGLRAVSAIGNRXXXXXXXXXXXXDSAESALQ 811
++DGTPWPAVG K TTYGG+SG A RP+ LRAV++I DSAES LQ
Sbjct: 745 KSDGTPWPAVGIAKRTTYGGVSGTAIRPIALRAVTSIARALPGFPILATGGIDSAESGLQ 804
Query: 812 FIMCGAPVVQICSAVQNQDFTVVDDYITGLKA 907
F+ GA V+Q+CSA+QNQDFTV++DY TGLKA
Sbjct: 805 FLHSGASVLQVCSAIQNQDFTVIEDYCTGLKA 836
>AL356457-3|CAH70570.1| 1025|Homo sapiens dihydropyrimidine
dehydrogenase protein.
Length = 1025
Score = 421 bits (1038), Expect = e-117
Identities = 194/272 (71%), Positives = 225/272 (82%)
Frame = +2
Query: 92 EQGWGFAVTKTFSLDKDMVTNVSPRIVRGVTSGENYGPGQGSFLNIELISEKCEAYWCQS 271
E GWGFA+TKTFSLDKD+VTNVSPRI+RG TSG YGPGQ SFLNIELISEK AYWCQS
Sbjct: 565 EAGWGFALTKTFSLDKDIVTNVSPRIIRGTTSGPMYGPGQSSFLNIELISEKTAAYWCQS 624
Query: 272 VTELKKDFPNKVIIASIMCSYNEEDWTLLSKKAEAAGADALELNLSCPHGMGESGMGLAC 451
VTELK DFP+ ++IASIMCSYN+ DWT L+KK+E +GADALELNLSCPHGMGE GMGLAC
Sbjct: 625 VTELKADFPDNIVIASIMCSYNKNDWTELAKKSEDSGADALELNLSCPHGMGERGMGLAC 684
Query: 452 GQDPVLVKGISQWVRKAIKIPFFVKLTPNITDIVSIAVAAYEGGASGVSAINTVSGLMSI 631
GQDP LV+ I +WVR+A++IPFF KLTPN+TDIVSIA AA EGGA+GV+A NTVSGLM +
Sbjct: 685 GQDPELVRNICRWVRQAVQIPFFAKLTPNVTDIVSIARAAKEGGANGVTATNTVSGLMGL 744
Query: 632 RADGTPWPAVGREKHTTYGGLSGNATRPMGLRAVSAIGNRXXXXXXXXXXXXDSAESALQ 811
++DGTPWPAVG K TTYGG+SG A RP+ LRAV++I DSAES LQ
Sbjct: 745 KSDGTPWPAVGIAKRTTYGGVSGTAIRPIALRAVTSIARALPGFPILATGGIDSAESGLQ 804
Query: 812 FIMCGAPVVQICSAVQNQDFTVVDDYITGLKA 907
F+ GA V+Q+CSA+QNQDFTV++DY TGLKA
Sbjct: 805 FLHSGASVLQVCSAIQNQDFTVIEDYCTGLKA 836
>AB003063-1|BAA89789.1| 1025|Homo sapiens dihydropyrimidine
dehydrogenase protein.
Length = 1025
Score = 421 bits (1038), Expect = e-117
Identities = 194/272 (71%), Positives = 225/272 (82%)
Frame = +2
Query: 92 EQGWGFAVTKTFSLDKDMVTNVSPRIVRGVTSGENYGPGQGSFLNIELISEKCEAYWCQS 271
E GWGFA+TKTFSLDKD+VTNVSPRI+RG TSG YGPGQ SFLNIELISEK AYWCQS
Sbjct: 565 EAGWGFALTKTFSLDKDIVTNVSPRIIRGTTSGPMYGPGQSSFLNIELISEKTAAYWCQS 624
Query: 272 VTELKKDFPNKVIIASIMCSYNEEDWTLLSKKAEAAGADALELNLSCPHGMGESGMGLAC 451
VTELK DFP+ ++IASIMCSYN+ DWT L+KK+E +GADALELNLSCPHGMGE GMGLAC
Sbjct: 625 VTELKADFPDNIVIASIMCSYNKNDWTELAKKSEDSGADALELNLSCPHGMGERGMGLAC 684
Query: 452 GQDPVLVKGISQWVRKAIKIPFFVKLTPNITDIVSIAVAAYEGGASGVSAINTVSGLMSI 631
GQDP LV+ I +WVR+A++IPFF KLTPN+TDIVSIA AA EGGA+GV+A NTVSGLM +
Sbjct: 685 GQDPELVRNICRWVRQAVQIPFFAKLTPNVTDIVSIARAAKEGGANGVTATNTVSGLMGL 744
Query: 632 RADGTPWPAVGREKHTTYGGLSGNATRPMGLRAVSAIGNRXXXXXXXXXXXXDSAESALQ 811
++DGTPWPAVG K TTYGG+SG A RP+ LRAV++I DSAES LQ
Sbjct: 745 KSDGTPWPAVGIAKRTTYGGVSGTAIRPIALRAVTSIARALPGFPILATGGIDSAESGLQ 804
Query: 812 FIMCGAPVVQICSAVQNQDFTVVDDYITGLKA 907
F+ GA V+Q+CSA+QNQDFTV++DY TGLKA
Sbjct: 805 FLHSGASVLQVCSAIQNQDFTVIEDYCTGLKA 836
>BC131778-1|AAI31779.1| 1025|Homo sapiens dihydropyrimidine
dehydrogenase protein.
Length = 1025
Score = 421 bits (1037), Expect = e-117
Identities = 193/272 (70%), Positives = 225/272 (82%)
Frame = +2
Query: 92 EQGWGFAVTKTFSLDKDMVTNVSPRIVRGVTSGENYGPGQGSFLNIELISEKCEAYWCQS 271
E GWGFA+TKTFSLDKD+VTNVSPRI+RG TSG YGPGQ SFLNIELISEK AYWCQS
Sbjct: 565 EAGWGFALTKTFSLDKDIVTNVSPRIIRGTTSGPMYGPGQSSFLNIELISEKTAAYWCQS 624
Query: 272 VTELKKDFPNKVIIASIMCSYNEEDWTLLSKKAEAAGADALELNLSCPHGMGESGMGLAC 451
VTELK DFP+ ++IASIMCSYN+ DWT L+KK+E +GADALELNLSCPHGMGE GMGLAC
Sbjct: 625 VTELKADFPDNIVIASIMCSYNKNDWTELAKKSEDSGADALELNLSCPHGMGERGMGLAC 684
Query: 452 GQDPVLVKGISQWVRKAIKIPFFVKLTPNITDIVSIAVAAYEGGASGVSAINTVSGLMSI 631
GQDP LV+ I +WVR+A++IPFF KLTPN+TDIVSIA AA EGGA+G++A NTVSGLM +
Sbjct: 685 GQDPELVRNICRWVRQAVQIPFFAKLTPNVTDIVSIARAAKEGGANGITATNTVSGLMGL 744
Query: 632 RADGTPWPAVGREKHTTYGGLSGNATRPMGLRAVSAIGNRXXXXXXXXXXXXDSAESALQ 811
++DGTPWPAVG K TTYGG+SG A RP+ LRAV++I DSAES LQ
Sbjct: 745 KSDGTPWPAVGIAKRTTYGGVSGTAIRPIALRAVTSIARALPGFPILATGGIDSAESGLQ 804
Query: 812 FIMCGAPVVQICSAVQNQDFTVVDDYITGLKA 907
F+ GA V+Q+CSA+QNQDFTV++DY TGLKA
Sbjct: 805 FLHSGASVLQVCSAIQNQDFTVIEDYCTGLKA 836
>X95670-1|CAA64973.1| 55|Homo sapiens dihydropyrimidine
dehydrogenase (NADP+) protein.
Length = 55
Score = 98.3 bits (234), Expect = 7e-20
Identities = 44/54 (81%), Positives = 47/54 (87%)
Frame = +2
Query: 140 DMVTNVSPRIVRGVTSGENYGPGQGSFLNIELISEKCEAYWCQSVTELKKDFPN 301
D+VTNVSPRI+RG TSG YGPGQ SFLNIELISEK AYWCQSVTELK DFP+
Sbjct: 1 DIVTNVSPRIIRGTTSGPMYGPGQSSFLNIELISEKTAAYWCQSVTELKADFPD 54
>U57655-1|AAB07049.1| 55|Homo sapiens dihydropyrimidine
dehydrogenase protein.
Length = 55
Score = 98.3 bits (234), Expect = 7e-20
Identities = 44/54 (81%), Positives = 47/54 (87%)
Frame = +2
Query: 140 DMVTNVSPRIVRGVTSGENYGPGQGSFLNIELISEKCEAYWCQSVTELKKDFPN 301
D+VTNVSPRI+RG TSG YGPGQ SFLNIELISEK AYWCQSVTELK DFP+
Sbjct: 1 DIVTNVSPRIIRGTTSGPMYGPGQSSFLNIELISEKTAAYWCQSVTELKADFPD 54
>AB058717-1|BAB47443.1| 1285|Homo sapiens KIAA1814 protein protein.
Length = 1285
Score = 34.7 bits (76), Expect = 0.91
Identities = 25/77 (32%), Positives = 30/77 (38%)
Frame = -2
Query: 798 SAESIPPIPRIGKPGSLLPIAETARSPIGRVALPDSPPYVVCFSRPTAGHGVPSALIDIN 619
S E+ PP P P L P A RSP G L PP P A P L+ N
Sbjct: 1133 SVETRPPPPPPPPPPPLPPPAHLGRSPAGPPVLHAPPP-------PNAALPPPPTLLASN 1185
Query: 618 PDTVFIADTPLAPPSYA 568
P+ + PP+ A
Sbjct: 1186 PEPALLQSLASLPPNQA 1202
>BC064391-1|AAH64391.1| 474|Homo sapiens coiled-coil domain
containing 6 protein.
Length = 474
Score = 31.5 bits (68), Expect = 8.5
Identities = 14/44 (31%), Positives = 15/44 (34%)
Frame = +1
Query: 1384 FXKXGPPPXXXXXGNAXPXXKPPPPGXFXXXPPXXXXQPNPXXH 1515
F + PPP P PPPP P QP P H
Sbjct: 423 FKRPTPPPSPNTQTPVQPPPPPPPPPMQPTVPSAATSQPTPSQH 466
>BC036757-1|AAH36757.2| 474|Homo sapiens coiled-coil domain
containing 6 protein.
Length = 474
Score = 31.5 bits (68), Expect = 8.5
Identities = 14/44 (31%), Positives = 15/44 (34%)
Frame = +1
Query: 1384 FXKXGPPPXXXXXGNAXPXXKPPPPGXFXXXPPXXXXQPNPXXH 1515
F + PPP P PPPP P QP P H
Sbjct: 423 FKRPTPPPSPNTQTPVQPPPPPPPPPMQPTVPSAATSQPTPSQH 466
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 199,138,684
Number of Sequences: 237096
Number of extensions: 4516285
Number of successful extensions: 10748
Number of sequences better than 10.0: 12
Number of HSP's better than 10.0 without gapping: 9072
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 10644
length of database: 76,859,062
effective HSP length: 93
effective length of database: 54,809,134
effective search space used: 22855408878
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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