Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= 030725E6_B03_e498_03.seq
(1616 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_P31939 Cluster: Bifunctional purine biosynthesis protei... 176 1e-42
UniRef50_Q4SHT8 Cluster: Chromosome 5 SCAF14581, whole genome sh... 167 7e-40
UniRef50_Q95QQ5 Cluster: Putative uncharacterized protein; n=2; ... 84 5e-32
UniRef50_Q0YKD5 Cluster: IMP cyclohydrolase; n=2; Geobacter|Rep:... 133 1e-29
UniRef50_A1K9K5 Cluster: Phosphoribosylaminoimidazolecarboxamide... 47 0.001
UniRef50_Q7X311 Cluster: Putative AICAR transformylase; n=1; unc... 47 0.002
UniRef50_Q8A155 Cluster: Bifunctional purine biosynthesis protei... 47 0.002
UniRef50_Q89B23 Cluster: Bifunctional purine biosynthesis protei... 44 0.015
UniRef50_A5E8X1 Cluster: Phosphoribosylaminoimidazolecarboxamide... 43 0.026
UniRef50_Q8ZAR3 Cluster: Bifunctional purine biosynthesis protei... 42 0.035
UniRef50_Q8F3W6 Cluster: Bifunctional purine biosynthesis protei... 42 0.046
UniRef50_A6G003 Cluster: Bifunctional phosphoribosylaminoimidazo... 41 0.080
UniRef50_P43852 Cluster: Bifunctional purine biosynthesis protei... 40 0.14
UniRef50_Q9HS43 Cluster: Phosphoribosylaminoimidazole-succinocar... 39 0.32
UniRef50_Q83EI4 Cluster: Phosphoribosylaminoimidazolecarboxamide... 38 0.57
UniRef50_A2SS05 Cluster: Phosphoribosylaminoimidazolecarboxamide... 38 0.57
UniRef50_Q9PC10 Cluster: Bifunctional purine biosynthesis protei... 38 0.57
UniRef50_A0JTW4 Cluster: Phosphoribosylaminoimidazolecarboxamide... 37 1.7
UniRef50_A0B9A9 Cluster: Phosphoribosylaminoimidazolecarboxamide... 37 1.7
UniRef50_Q5KN32 Cluster: IMP cyclohydrolase, putative; n=1; Filo... 36 2.3
UniRef50_O67775 Cluster: Bifunctional purine biosynthesis protei... 36 3.0
UniRef50_Q5B840 Cluster: Putative uncharacterized protein; n=1; ... 36 4.0
>UniRef50_P31939 Cluster: Bifunctional purine biosynthesis protein
PURH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3)
(5-aminoimidazole-4-carboxamide ribonucleotide
formyltransferase) (AICAR transformylase); IMP
cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=105; cellular organisms|Rep:
Bifunctional purine biosynthesis protein PURH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3)
(5-aminoimidazole-4-carboxamide ribonucleotide
formyltransferase) (AICAR transformylase); IMP
cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Homo sapiens (Human)
Length = 592
Score = 176 bits (429), Expect = 1e-42
Identities = 89/151 (58%), Positives = 101/151 (66%)
Frame = +3
Query: 66 GIVAPGYTPEALNILRKKKGGNYCVLQMDPSYEPDLTERKTLYGLSLEQRRNDAKITAGL 245
GI+APGY EAL IL KKK GNYCVLQMD SY+PD E +TL+GL L Q+RN+ + L
Sbjct: 340 GIIAPGYEEEALTILSKKKNGNYCVLQMDQSYKPDENEVRTLFGLHLSQKRNNGVVDKSL 399
Query: 246 FGNIVTAKKELPEEAVRDLIVATIALKYTQSNSVCYARXXXXXXXXXXXXSRIHCTRLAG 425
F N+VT K+LPE A+RDLIVATIA+KYTQSNSVCYA+ SRIHCTRLAG
Sbjct: 400 FSNVVTKNKDLPESALRDLIVATIAVKYTQSNSVCYAKNGQVIGIGAGQQSRIHCTRLAG 459
Query: 426 GKAVLWRXRSHPAVLXAXDAFXAXVTRAXAS 518
KA W R HP VL F V RA S
Sbjct: 460 DKANYWWLRHHPQVLSM--KFKTGVKRAEIS 488
>UniRef50_Q4SHT8 Cluster: Chromosome 5 SCAF14581, whole genome
shotgun sequence; n=3; Euteleostomi|Rep: Chromosome 5
SCAF14581, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 628
Score = 167 bits (406), Expect = 7e-40
Identities = 88/153 (57%), Positives = 99/153 (64%), Gaps = 5/153 (3%)
Frame = +3
Query: 27 VDPPGSAGNS-----ARGGIVAPGYTPEALNILRKKKGGNYCVLQMDPSYEPDLTERKTL 191
V P S GN+ GI+APGY EAL IL KKK GNYCVLQMDP YEPD TE + L
Sbjct: 327 VSSPASCGNNRIFSQVSDGIIAPGYDEEALKILSKKKNGNYCVLQMDPEYEPDETEVRVL 386
Query: 192 YGLSLEQRRNDAKITAGLFGNIVTAKKELPEEAVRDLIVATIALKYTQSNSVCYARXXXX 371
+GL L+Q+RN I F N+V +K L E+A+RDL VATIALKYTQSNSVCYA+
Sbjct: 387 FGLYLKQKRNGGIINKEFFSNVV-SKGSLSEDALRDLTVATIALKYTQSNSVCYAKDGQV 445
Query: 372 XXXXXXXXSRIHCTRLAGGKAVLWRXRSHPAVL 470
SRIHCTRLAG KA W R HP VL
Sbjct: 446 IGIGAGQQSRIHCTRLAGDKADNWWLRHHPRVL 478
>UniRef50_Q95QQ5 Cluster: Putative uncharacterized protein; n=2;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 420
Score = 84.2 bits (199), Expect(2) = 5e-32
Identities = 36/73 (49%), Positives = 53/73 (72%)
Frame = +3
Query: 66 GIVAPGYTPEALNILRKKKGGNYCVLQMDPSYEPDLTERKTLYGLSLEQRRNDAKITAGL 245
G+VAP + P AL++L KKK GNYCVL+++P+Y P TE +T++GL L Q+RN+A I A
Sbjct: 134 GVVAPDFDPAALSLLAKKKNGNYCVLKINPNYLPSETEERTVFGLRLRQKRNNAVINAET 193
Query: 246 FGNIVTAKKELPE 284
F N+V + E+ +
Sbjct: 194 FNNVVGSANEVSD 206
Score = 78.6 bits (185), Expect(2) = 5e-32
Identities = 38/66 (57%), Positives = 44/66 (66%)
Frame = +3
Query: 273 ELPEEAVRDLIVATIALKYTQSNSVCYARXXXXXXXXXXXXSRIHCTRLAGGKAVLWRXR 452
+L ++A+ DLIVATIALKY QSNSVC+A SRIHCTRLAG KA+ W R
Sbjct: 237 QLNKQAIDDLIVATIALKYAQSNSVCFAHRGQVIGMGAGQQSRIHCTRLAGDKAMNWWLR 296
Query: 453 SHPAVL 470
HP VL
Sbjct: 297 QHPTVL 302
>UniRef50_Q0YKD5 Cluster: IMP cyclohydrolase; n=2; Geobacter|Rep:
IMP cyclohydrolase - Geobacter sp. FRC-32
Length = 388
Score = 133 bits (322), Expect = 1e-29
Identities = 65/134 (48%), Positives = 83/134 (61%)
Frame = +3
Query: 69 IVAPGYTPEALNILRKKKGGNYCVLQMDPSYEPDLTERKTLYGLSLEQRRNDAKITAGLF 248
I+APG+ P AL IL+ KK G Y +LQ+DP YEP E++ ++G L+Q+RN A ++A LF
Sbjct: 137 IIAPGFEPAALEILKAKKQGTYLILQIDPDYEPAEIEQREVFGFGLQQKRNTAPVSAALF 196
Query: 249 GNIVTAKKELPEEAVRDLIVATIALKYTQSNSVCYARXXXXXXXXXXXXSRIHCTRLAGG 428
N VT K + + LIVATIALK+TQSNSVC A SR+HCTRLA
Sbjct: 197 QNSVTIGKSVSPDITETLIVATIALKFTQSNSVCLAYEGQVIGMGAGQQSRVHCTRLACD 256
Query: 429 KAVLWRXRSHPAVL 470
KA W + HP L
Sbjct: 257 KADKWLLQQHPKTL 270
>UniRef50_A1K9K5 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase; n=2; Bacteria|Rep:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase - Azoarcus sp.
(strain BH72)
Length = 527
Score = 47.2 bits (107), Expect = 0.001
Identities = 40/140 (28%), Positives = 63/140 (45%)
Frame = +3
Query: 69 IVAPGYTPEALNILRKKKGGNYCVLQMDPSYEPDLTERKTLYGLSLEQRRNDAKITAGLF 248
++AP YT +AL +LR K+ N VL + K + G L Q ++A+I L
Sbjct: 342 LIAPSYTADALELLRAKQ--NVRVLTCPLGKPSGALDYKRVGGGLLVQSADEARIQ--LA 397
Query: 249 GNIVTAKKELPEEAVRDLIVATIALKYTQSNSVCYARXXXXXXXXXXXXSRIHCTRLAGG 428
V K+ + +RD++ A KY +SN++ Y + SR+ R+A
Sbjct: 398 DLKVVTKRAPSDTELRDMLFAWRVAKYVKSNAIVYCKDGMTIGVGAGQMSRVDSARIAKI 457
Query: 429 KAVLWRXRSHPAVLXAXDAF 488
KA + P + A DAF
Sbjct: 458 KAEN-AGLAIPGCVVASDAF 476
>UniRef50_Q7X311 Cluster: Putative AICAR transformylase; n=1;
uncultured Acidobacteria bacterium|Rep: Putative AICAR
transformylase - uncultured Acidobacteria bacterium
Length = 571
Score = 46.8 bits (106), Expect = 0.002
Identities = 38/124 (30%), Positives = 57/124 (45%)
Frame = +3
Query: 69 IVAPGYTPEALNILRKKKGGNYCVLQMDPSYEPDLTERKTLYGLSLEQRRNDAKITAGLF 248
+VA Y AL++LR KK N VL+ E + + G L Q + ++
Sbjct: 389 VVATDYEEAALDVLRSKK--NLRVLRAARLTRAKGVEYRQISGGMLVQTSDTHRLDKNDL 446
Query: 249 GNIVTAKKELPEEAVRDLIVATIALKYTQSNSVCYARXXXXXXXXXXXXSRIHCTRLAGG 428
NIVT K+E E + DL+ A K+T+SN++ YAR SR+ +L
Sbjct: 447 -NIVT-KREPTESEISDLLFAWTVCKHTKSNAIVYARDKQTVGVGAGQMSRVDSVKLGAM 504
Query: 429 KAVL 440
+A L
Sbjct: 505 RAQL 508
>UniRef50_Q8A155 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=5; Bacteroides|Rep: Bifunctional
purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Bacteroides thetaiotaomicron
Length = 507
Score = 46.8 bits (106), Expect = 0.002
Identities = 43/140 (30%), Positives = 66/140 (47%)
Frame = +3
Query: 69 IVAPGYTPEALNILRKKKGGNYCVLQMDPSYEPDLTERKTLYGLSLEQRRNDAKITAGLF 248
I+AP Y +AL IL +KK N +L + P R L G+ ++ + + + A L
Sbjct: 323 IIAPDYDVDALEILGQKK--NRIILVRKEAKLPKKQFRALLNGVLVQDKDMNIETVADL- 379
Query: 249 GNIVTAKKELPEEAVRDLIVATIALKYTQSNSVCYARXXXXXXXXXXXXSRIHCTRLAGG 428
VT K PEE V DL+ A +K ++SN++ A+ SR+ + A
Sbjct: 380 -RTVTDKAPTPEE-VEDLLFANKIVKNSKSNAIVLAKGKQLLASGVGQTSRVDALKQAIE 437
Query: 429 KAVLWRXRSHPAVLXAXDAF 488
KA + + AV+ A DAF
Sbjct: 438 KAKSFGFDLNGAVM-ASDAF 456
>UniRef50_Q89B23 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=2; Buchnera aphidicola (Baizongia
pistaciae)|Rep: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Buchnera aphidicola subsp.
Baizongia pistaciae
Length = 529
Score = 43.6 bits (98), Expect = 0.015
Identities = 35/124 (28%), Positives = 58/124 (46%), Gaps = 2/124 (1%)
Frame = +3
Query: 69 IVAPGYTPEALNILRKKKGGNYCVLQMDPSYE--PDLTERKTLYGLSLEQRRNDAKITAG 242
I+AP +T EA I KK N +++ DP+Y + K++YG L Q ++ I
Sbjct: 342 ILAPDFTQEAKKIFDKKP--NLRIIKYDPNYNYLNYNIDIKSIYGDILVQSNTNSIININ 399
Query: 243 LFGNIVTAKKELPEEAVRDLIVATIALKYTQSNSVCYARXXXXXXXXXXXXSRIHCTRLA 422
+ + +KK E+ + D A +K+ +SNS+ + SRI T++A
Sbjct: 400 QWD--IVSKKRPNEQEINDAKFALRVVKHLKSNSIVLIKNQITISIGSGQTSRIDATKIA 457
Query: 423 GGKA 434
KA
Sbjct: 458 IYKA 461
>UniRef50_A5E8X1 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase /IMP cyclohydrolase; n=4;
Bacteria|Rep: Phosphoribosylaminoimidazolecarboxamide
formyltransferase /IMP cyclohydrolase - Bradyrhizobium
sp. (strain BTAi1 / ATCC BAA-1182)
Length = 530
Score = 42.7 bits (96), Expect = 0.026
Identities = 36/124 (29%), Positives = 57/124 (45%), Gaps = 1/124 (0%)
Frame = +3
Query: 69 IVAPGYTPEALNILRKKKGGNYCVLQMDPSYEPDLTERKTLYGLSLEQRRNDAKITAGLF 248
I+AP T EA+ ++ +K + P KT+ G L Q R++A + +
Sbjct: 336 IIAPDATEEAIAVIAARKTLRLLLAGALPDPREAGLTAKTVAGGLLVQSRDNA-VVDDMT 394
Query: 249 GNIVTAKKELPEEA-VRDLIVATIALKYTQSNSVCYARXXXXXXXXXXXXSRIHCTRLAG 425
+VT K P EA +RDL A K+ +SN++ YA+ SR+ R+A
Sbjct: 395 LKVVT--KRAPTEAELRDLRFAFRVAKHVKSNTIIYAKDSATVGIGAGQMSRVDSARIAA 452
Query: 426 GKAV 437
KA+
Sbjct: 453 RKAL 456
>UniRef50_Q8ZAR3 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=59; Proteobacteria|Rep:
Bifunctional purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Yersinia pestis
Length = 529
Score = 42.3 bits (95), Expect = 0.035
Identities = 32/122 (26%), Positives = 56/122 (45%)
Frame = +3
Query: 69 IVAPGYTPEALNILRKKKGGNYCVLQMDPSYEPDLTERKTLYGLSLEQRRNDAKITAGLF 248
I+AP + +AL +L K+ + L ++ GL L Q R+ +TA
Sbjct: 343 IIAPTVSSDALALLAAKQNVRVLTCGQWQARSAGLDFKRVNGGL-LVQERDLGMVTAADL 401
Query: 249 GNIVTAKKELPEEAVRDLIVATIALKYTQSNSVCYARXXXXXXXXXXXXSRIHCTRLAGG 428
V +K++ E+ +RD + K+ +SN++ YAR SR++ ++AG
Sbjct: 402 R--VVSKRQPTEQELRDALFCWKVAKFVKSNAIVYARDNMTIGIGAGQMSRVYSAKIAGI 459
Query: 429 KA 434
KA
Sbjct: 460 KA 461
>UniRef50_Q8F3W6 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=6; Bacteria|Rep: Bifunctional
purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Leptospira interrogans
Length = 511
Score = 41.9 bits (94), Expect = 0.046
Identities = 30/124 (24%), Positives = 54/124 (43%)
Frame = +3
Query: 66 GIVAPGYTPEALNILRKKKGGNYCVLQMDPSYEPDLTERKTLYGLSLEQRRNDAKITAGL 245
G++A +T EAL + KK +Q +L R +GL ++ R L
Sbjct: 324 GVIAQKFTQEALEVFSKKPNIRLIEIQDFKEALDELDLRPIHHGLLIQDRDYTTITEKDL 383
Query: 246 FGNIVTAKKELPEEAVRDLIVATIALKYTQSNSVCYARXXXXXXXXXXXXSRIHCTRLAG 425
+VT K+ P++ +R L+ A +++ +SN++ Y SR+ +L
Sbjct: 384 --KVVTKKQPSPDD-IRGLMFAWSCVRFIKSNAIVYTEENATLGIGAGQMSRVDSVQLGA 440
Query: 426 GKAV 437
KA+
Sbjct: 441 NKAL 444
>UniRef50_A6G003 Cluster: Bifunctional
phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase; n=1; Plesiocystis
pacifica SIR-1|Rep: Bifunctional
phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase - Plesiocystis
pacifica SIR-1
Length = 543
Score = 41.1 bits (92), Expect = 0.080
Identities = 37/125 (29%), Positives = 58/125 (46%), Gaps = 3/125 (2%)
Frame = +3
Query: 69 IVAPGYTPEALNILRKKKGGNYCVLQMDPSYE-PDLT--ERKTLYGLSLEQRRNDAKITA 239
IVAPGYTPEA IL KKK +L++ +E DL +++ G L QR + + A
Sbjct: 358 IVAPGYTPEAREILAKKK--RLRLLEIPAMFEGRDLAPLRLRSVAGGLLVQREDLIGVAA 415
Query: 240 GLFGNIVTAKKELPEEAVRDLIVATIALKYTQSNSVCYARXXXXXXXXXXXXSRIHCTRL 419
G + T +K +E + L + K+ +SN++ + SR+ R
Sbjct: 416 AA-GEVPTQRKPSADE-LASLDLGQRVCKHVRSNAIVLVKDGVTVGVGGGQTSRVEAVRQ 473
Query: 420 AGGKA 434
A +A
Sbjct: 474 AISRA 478
>UniRef50_P43852 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=88; Bacteria|Rep: Bifunctional
purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Haemophilus influenzae
Length = 532
Score = 40.3 bits (90), Expect = 0.14
Identities = 30/123 (24%), Positives = 58/123 (47%), Gaps = 1/123 (0%)
Frame = +3
Query: 69 IVAPGYTPEALNILRKKKGGNYCVLQMDPSYEPDLTERKTLYGLSLEQRRNDAKI-TAGL 245
I+AP + EA ++++KK S L ++ GL ++ DA + G+
Sbjct: 346 IIAPKVSAEAQEVMKRKKNVRLLECGEWTSRSERLDFKRVNGGLLVQ----DADLGMVGV 401
Query: 246 FGNIVTAKKELPEEAVRDLIVATIALKYTQSNSVCYARXXXXXXXXXXXXSRIHCTRLAG 425
V +K++ E+ ++DL+ K+ +SN++ YA+ SR++ ++AG
Sbjct: 402 DDLKVVSKRQPTEQELKDLLFCWKVAKFVKSNAIVYAKDNQTIGIGAGQMSRVYSAKIAG 461
Query: 426 GKA 434
KA
Sbjct: 462 IKA 464
>UniRef50_Q9HS43 Cluster:
Phosphoribosylaminoimidazole-succinocarboxamide
formyltransferase; n=5; Halobacteriaceae|Rep:
Phosphoribosylaminoimidazole-succinocarboxamide
formyltransferase - Halobacterium salinarium
(Halobacterium halobium)
Length = 595
Score = 39.1 bits (87), Expect = 0.32
Identities = 36/123 (29%), Positives = 52/123 (42%), Gaps = 1/123 (0%)
Frame = +3
Query: 69 IVAPGYTPEALNILRKKKGGNYCVLQMDP-SYEPDLTERKTLYGLSLEQRRNDAKITAGL 245
+VAPGYT +A+++L K N VL + P L G L Q RN TA
Sbjct: 406 VVAPGYTDDAVDVLTAK--SNLRVLDVGTLDGTPAPVTETPLVGGRLVQERNTWAPTADD 463
Query: 246 FGNIVTAKKELPEEAVRDLIVATIALKYTQSNSVCYARXXXXXXXXXXXXSRIHCTRLAG 425
+VT K+E V ++ A L + +SN + +A SR+ +A
Sbjct: 464 L-EVVT-KREPTAAEVETMLFAWRVLTHVKSNGILFAAGTETVGLGVGQVSRVDAVEIAA 521
Query: 426 GKA 434
KA
Sbjct: 522 KKA 524
>UniRef50_Q83EI4 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase; n=5; Coxiella
burnetii|Rep: Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase - Coxiella burnetii
Length = 526
Score = 38.3 bits (85), Expect = 0.57
Identities = 34/123 (27%), Positives = 57/123 (46%), Gaps = 1/123 (0%)
Frame = +3
Query: 69 IVAPGYTPEALNILRKKKGGNYCVLQMDPSYEPDLTER-KTLYGLSLEQRRNDAKITAGL 245
I+AP + E L +L+ K N VL+ P +T ++ G L Q + K +
Sbjct: 340 IIAPDFPAETLRLLQTKP--NLRVLRGQPLDSSQITYSFHSITGGVLCQEADATKFSDET 397
Query: 246 FGNIVTAKKELPEEAVRDLIVATIALKYTQSNSVCYARXXXXXXXXXXXXSRIHCTRLAG 425
F +VT ++ +E +DL A +KY +SN++ YA+ SR+ ++A
Sbjct: 398 F-TVVTRRQPTAKEQ-QDLYFAWQIVKYVKSNAIVYAKDHATLGIGSGQTSRVFAAKIAI 455
Query: 426 GKA 434
KA
Sbjct: 456 LKA 458
>UniRef50_A2SS05 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase; n=3;
Methanomicrobiales|Rep:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase -
Methanocorpusculum labreanum (strain ATCC 43576 / DSM
4855 / Z)
Length = 497
Score = 38.3 bits (85), Expect = 0.57
Identities = 38/140 (27%), Positives = 65/140 (46%)
Frame = +3
Query: 69 IVAPGYTPEALNILRKKKGGNYCVLQMDPSYEPDLTERKTLYGLSLEQRRNDAKITAGLF 248
++AP ++ EA +++KK+ +L P EP E +T+ G L QR T
Sbjct: 317 LIAPSFSDEAREMMKKKENMRLLIL---PPAEP-ADEIRTIDGGILVQR--TPAYTED-- 368
Query: 249 GNIVTAKKELPEEAVRDLIVATIALKYTQSNSVCYARXXXXXXXXXXXXSRIHCTRLAGG 428
+V+ + P+E V L +A ++Y +SN++ YA +R+ +LA
Sbjct: 369 WKVVSKRAPTPDE-VEALKLAWKVVEYAKSNAIIYANKTETVGIGVGQMNRVDSAKLAIQ 427
Query: 429 KAVLWRXRSHPAVLXAXDAF 488
KA + R+ + A DAF
Sbjct: 428 KAAEF-GRTMQGTVIASDAF 446
>UniRef50_Q9PC10 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=214; cellular organisms|Rep:
Bifunctional purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Xylella fastidiosa
Length = 527
Score = 38.3 bits (85), Expect = 0.57
Identities = 35/123 (28%), Positives = 57/123 (46%), Gaps = 1/123 (0%)
Frame = +3
Query: 69 IVAPGYTPEALNILRKKKGGNYCVLQMDPSYEPDLTERKTLYGLSLEQRRNDAKITAGLF 248
++AP Y +AL KK N VL++ + + + K + L Q + I +
Sbjct: 342 LIAPDYDADALAYATKK--ANVRVLRIPSTGVMNRYDFKRIGSGLLVQSTDSLNIHSDAL 399
Query: 249 GNIVTAKKELPEEAV-RDLIVATIALKYTQSNSVCYARXXXXXXXXXXXXSRIHCTRLAG 425
+VT + P +A RDL+ A KY +SN++ YA+ SR++ R+AG
Sbjct: 400 -KVVT--QLAPTDAQQRDLLFAWHVAKYVKSNAIVYAKDNRTIGIGAGQMSRVYSARIAG 456
Query: 426 GKA 434
KA
Sbjct: 457 IKA 459
>UniRef50_A0JTW4 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase; n=2;
Arthrobacter|Rep:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase - Arthrobacter sp.
(strain FB24)
Length = 559
Score = 36.7 bits (81), Expect = 1.7
Identities = 40/159 (25%), Positives = 63/159 (39%), Gaps = 1/159 (0%)
Frame = +3
Query: 69 IVAPGYTPEALNILRKKKGGNYCVLQMDPSYEPDLTERKTLYGLSLEQRRNDAKITAGLF 248
++APG+ EA+ IL KKK N +L + Y TE + + G L Q +
Sbjct: 346 VIAPGFEDEAVEILSKKK--NIRLLALPEGYGRYPTEFRQVSGGMLVQAADKVDAEGDNP 403
Query: 249 GNIVTAKKELPEEA-VRDLIVATIALKYTQSNSVCYARXXXXXXXXXXXXSRIHCTRLAG 425
N A E + A + DL A A + +SN++ A +R+ +LA
Sbjct: 404 ANWTLAAGEAADAATLADLAFAWTACRAAKSNAILLADHGAAVGIGMGQVNRLDSCKLAV 463
Query: 426 GKAVLWRXRSHPAVLXAXDAFXAXVTRAXASXRLSTXTV 542
+A + V A A T A A+ + + V
Sbjct: 464 ERANTLGVQVESDVEGAGGAAGPSTTEASAAPQRARGAV 502
>UniRef50_A0B9A9 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase; n=1; Methanosaeta thermophila PT|Rep:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase - Methanosaeta thermophila (strain DSM
6194 / PT) (Methanothrixthermophila (strain DSM 6194 /
PT))
Length = 451
Score = 36.7 bits (81), Expect = 1.7
Identities = 36/133 (27%), Positives = 55/133 (41%), Gaps = 4/133 (3%)
Frame = +3
Query: 48 GNSARGGIVAPGYTPEALNILRKKKGGNYCVLQMDPSYEPDLTER----KTLYGLSLEQR 215
G+S ++APGY P+AL +L + K + D D R ++++G + Q
Sbjct: 255 GDSFVEVLIAPGYEPDALELLTRNKPNRRILDIGDMLQRKDELYRGHAFRSVFGGMMLQD 314
Query: 216 RNDAKITAGLFGNIVTAKKELPEEAVRDLIVATIALKYTQSNSVCYARXXXXXXXXXXXX 395
+ I L +VT + PEE R L A KY +SN++ Y
Sbjct: 315 YDREDI---LEWRVVTQRSPTPEEN-RALRFAWKVTKYVKSNALVYTTADRTIGIGSGQV 370
Query: 396 SRIHCTRLAGGKA 434
SR+ R KA
Sbjct: 371 SRVDSARFGAEKA 383
>UniRef50_Q5KN32 Cluster: IMP cyclohydrolase, putative; n=1;
Filobasidiella neoformans|Rep: IMP cyclohydrolase,
putative - Cryptococcus neoformans (Filobasidiella
neoformans)
Length = 120
Score = 36.3 bits (80), Expect = 2.3
Identities = 17/24 (70%), Positives = 22/24 (91%), Gaps = 1/24 (4%)
Frame = +3
Query: 288 AVRDLIVATIAL-KYTQSNSVCYA 356
+V DL+VAT+AL KYT+SNSVC+A
Sbjct: 15 SVTDLVVATLALNKYTRSNSVCHA 38
>UniRef50_O67775 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=9; Bacteria|Rep: Bifunctional
purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Aquifex aeolicus
Length = 506
Score = 35.9 bits (79), Expect = 3.0
Identities = 35/122 (28%), Positives = 56/122 (45%)
Frame = +3
Query: 69 IVAPGYTPEALNILRKKKGGNYCVLQMDPSYEPDLTERKTLYGLSLEQRRNDAKITAGLF 248
++AP Y EAL L +KK N V++ ++ +K G L+ D + L
Sbjct: 325 VIAPDYDEEALRELSRKK--NLRVIRFF-GFQHAFDVKKVSGGYLLQDE--DTVLYEKL- 378
Query: 249 GNIVTAKKELPEEAVRDLIVATIALKYTQSNSVCYARXXXXXXXXXXXXSRIHCTRLAGG 428
+VT K+E E + DL+ A +K+T+SN+V A+ SR+ + A
Sbjct: 379 -QVVT-KREPTAEEMEDLLFAWKVVKHTKSNAVVIAKNGQTLGIGSGNVSRVDSLKCAIN 436
Query: 429 KA 434
KA
Sbjct: 437 KA 438
>UniRef50_Q5B840 Cluster: Putative uncharacterized protein; n=1;
Emericella nidulans|Rep: Putative uncharacterized
protein - Emericella nidulans (Aspergillus nidulans)
Length = 822
Score = 35.5 bits (78), Expect = 4.0
Identities = 24/75 (32%), Positives = 35/75 (46%), Gaps = 5/75 (6%)
Frame = -1
Query: 461 RVRAXPPQHRLAARQPR-AVDTRLLTGAYAY---HLPVPGVTDGVALSVLERDGRHDQIP 294
R + P H +R A++ LTG Y Y H V G A+ + + DG H Q+P
Sbjct: 325 RAMSLMPDHTSLSRGGFVAIEVLALTGLYLYSIDHRSSAHVYVGHAIRIAQMDGMHTQLP 384
Query: 293 NSLLG-QLLLRCYNI 252
LG + + RC N+
Sbjct: 385 EDELGLETVARCRNL 399
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 559,235,373
Number of Sequences: 1657284
Number of extensions: 9462486
Number of successful extensions: 29114
Number of sequences better than 10.0: 22
Number of HSP's better than 10.0 without gapping: 28156
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 29098
length of database: 575,637,011
effective HSP length: 104
effective length of database: 403,279,475
effective search space used: 175023292150
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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