Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= 030725E6_A07_e529_01.seq
(1524 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
U37100-1|AAC17469.1| 316|Homo sapiens aldose reductase-like pep... 235 3e-61
CR541801-1|CAG46600.1| 316|Homo sapiens AKR1B10 protein. 235 3e-61
BT006794-1|AAP35440.1| 316|Homo sapiens aldo-keto reductase fam... 235 3e-61
BC008837-1|AAH08837.1| 316|Homo sapiens aldo-keto reductase fam... 235 3e-61
AF052577-1|AAC36465.1| 316|Homo sapiens aldo-keto reductase pro... 235 3e-61
X15414-1|CAA33460.1| 316|Homo sapiens protein ( Human mRNA for ... 233 1e-60
M59783-1|AAA51712.1| 316|Homo sapiens aldose reductase protein. 233 1e-60
M34720-1|AAA35560.1| 316|Homo sapiens protein ( Human aldose re... 233 1e-60
J05474-1|AAA51715.1| 316|Homo sapiens aldose reductase protein. 233 1e-60
J05017-1|AAA51714.1| 316|Homo sapiens ALDR1 protein. 233 1e-60
J04795-1|AAA51713.1| 316|Homo sapiens ALDR1 protein. 233 1e-60
BT019859-1|AAV38662.1| 316|Homo sapiens aldo-keto reductase fam... 233 1e-60
BC010391-1|AAH10391.1| 316|Homo sapiens aldo-keto reductase fam... 233 1e-60
BC000260-1|AAH00260.1| 316|Homo sapiens aldo-keto reductase fam... 233 1e-60
AF328729-1|AAN09721.1| 316|Homo sapiens CTCL tumor antigen HD-C... 233 1e-60
AF032455-1|AAB88851.1| 316|Homo sapiens aldose reductase protein. 233 1e-60
CR542203-1|CAG47000.1| 316|Homo sapiens AKR1B1 protein. 232 2e-60
AF524864-1|AAO13380.1| 316|Homo sapiens aldo-ketoreductase prot... 232 2e-60
CR450351-1|CAG29347.1| 316|Homo sapiens AKR1B1 protein. 231 4e-60
BC005387-1|AAH05387.1| 316|Homo sapiens aldo-keto reductase fam... 227 6e-59
AB209796-1|BAD93033.1| 260|Homo sapiens aldo-keto reductase fam... 220 9e-57
J04794-1|AAA51711.1| 325|Homo sapiens ALDR1 protein. 216 2e-55
CR457010-1|CAG33291.1| 325|Homo sapiens AKR1A1 protein. 216 2e-55
BT007003-1|AAP35649.1| 325|Homo sapiens aldo-keto reductase fam... 216 2e-55
BC005394-1|AAH05394.1| 325|Homo sapiens aldo-keto reductase fam... 216 2e-55
BC000670-1|AAH00670.1| 325|Homo sapiens aldo-keto reductase fam... 216 2e-55
AL355480-3|CAI22459.1| 325|Homo sapiens aldo-keto reductase fam... 216 2e-55
AF112485-1|AAF01260.1| 325|Homo sapiens aldehyde reductase prot... 216 2e-55
AF036683-1|AAB92369.1| 325|Homo sapiens aldehyde reductase prot... 216 2e-55
U05861-1|AAA18115.1| 323|Homo sapiens hepatic dihydrodiol dehyd... 206 1e-52
U05684-1|AAA16227.1| 323|Homo sapiens dihydrodiol dehydrogenase... 206 1e-52
M86609-1|AAB02880.1| 323|Homo sapiens dihydrodiol dehydrogenase... 206 1e-52
D26124-1|BAA05121.1| 306|Homo sapiens dihydrodiol dehydrogenase... 206 1e-52
BT007197-1|AAP35861.1| 323|Homo sapiens aldo-keto reductase fam... 206 1e-52
BC040210-1|AAH40210.1| 323|Homo sapiens aldo-keto reductase fam... 206 1e-52
BC020216-1|AAH20216.1| 323|Homo sapiens aldo-keto reductase fam... 206 1e-52
BC015490-1|AAH15490.1| 323|Homo sapiens aldo-keto reductase fam... 206 1e-52
AL713867-3|CAI16410.1| 247|Homo sapiens aldo-keto reductase fam... 206 1e-52
AL713867-2|CAI16409.1| 323|Homo sapiens aldo-keto reductase fam... 206 1e-52
AB032150-1|BAA92886.1| 323|Homo sapiens 20 alph-hydroxysteroid ... 206 1e-52
AB031083-1|BAA92883.1| 323|Homo sapiens 20 alpha-hydroxysteroid... 206 1e-52
U05598-1|AAA20937.1| 323|Homo sapiens dihydrodiol dehydrogenase... 206 2e-52
S68330-1|AAD14013.1| 323|Homo sapiens chlordecone reductase hom... 206 2e-52
BT006653-1|AAP35299.1| 323|Homo sapiens aldo-keto reductase fam... 206 2e-52
BC063574-1|AAH63574.1| 323|Homo sapiens aldo-keto reductase fam... 206 2e-52
BC007024-1|AAH07024.1| 323|Homo sapiens aldo-keto reductase fam... 206 2e-52
AL713867-1|CAI16408.1| 323|Homo sapiens aldo-keto reductase fam... 206 2e-52
AL391427-1|CAI14726.1| 323|Homo sapiens aldo-keto reductase fam... 206 2e-52
AB032153-1|BAA92891.1| 323|Homo sapiens bile acid-binding prote... 206 2e-52
AB031084-1|BAA92884.1| 323|Homo sapiens bile acid-binding prote... 206 2e-52
AB021654-1|BAA36169.1| 323|Homo sapiens DD2/bile acid-binding p... 206 2e-52
D17793-1|BAA04619.2| 325|Homo sapiens KIAA0119 protein. 205 3e-52
BT007286-1|AAP35950.1| 323|Homo sapiens aldo-keto reductase fam... 205 3e-52
BC019230-1|AAH19230.1| 323|Homo sapiens aldo-keto reductase fam... 205 3e-52
BC001479-1|AAH01479.1| 323|Homo sapiens aldo-keto reductase fam... 205 3e-52
AL391427-4|CAI14729.1| 323|Homo sapiens aldo-keto reductase fam... 205 3e-52
AB032157-1|BAA92892.1| 323|Homo sapiens prostaglandin F synthas... 205 3e-52
AB018580-1|BAA88488.1| 323|Homo sapiens hluPGFS protein. 205 3e-52
L32592-1|AAB38486.1| 323|Homo sapiens dihydrodiol dehydrogenase... 205 4e-52
S68288-1|AAD14011.1| 323|Homo sapiens chlordecone reductase hom... 203 2e-51
L43839-1|AAB41916.1| 323|Homo sapiens 3-alpha-hydroxysteroid de... 202 3e-51
AF149416-1|AAF07272.2| 323|Homo sapiens 3-alpha hydroxysteroid ... 202 3e-51
S68290-1|AAD14012.1| 320|Homo sapiens chlordecone reductase hom... 201 5e-51
DQ269985-1|ABB76132.1| 323|Homo sapiens type II 3a-hydroxystero... 198 3e-50
AB045829-1|BAA99542.1| 323|Homo sapiens 3alpha-hydroxysteroid d... 192 3e-48
S68287-1|AAD14010.1| 323|Homo sapiens chlordecone reductase pro... 192 4e-48
M33375-1|AAA35658.1| 308|Homo sapiens protein ( Human chlordeco... 192 4e-48
D26125-1|BAA05122.1| 321|Homo sapiens 3 alpha-hydroxysteroid/di... 192 4e-48
AB032163-1|BAA92893.1| 323|Homo sapiens dihydrodiol dehydrogena... 192 4e-48
AB031085-1|BAA92885.1| 323|Homo sapiens dihydrodiol dehydrogena... 192 4e-48
BC020744-1|AAH20744.1| 323|Homo sapiens aldo-keto reductase fam... 191 5e-48
AL355303-2|CAI14202.1| 323|Homo sapiens aldo-keto reductase fam... 191 5e-48
AB209017-1|BAD92254.1| 286|Homo sapiens aldo-keto reductase fam... 191 7e-48
Z28339-1|CAA82193.1| 326|Homo sapiens delta 4-3-oxosteroid 5 be... 190 9e-48
BC130627-1|AAI30628.1| 326|Homo sapiens aldo-keto reductase fam... 190 9e-48
BC130625-1|AAI30626.1| 326|Homo sapiens aldo-keto reductase fam... 190 9e-48
AF283659-1|AAG39381.1| 326|Homo sapiens 5-beta steroid reductas... 190 9e-48
BC002862-1|AAH02862.1| 307|Homo sapiens AKR1CL2 protein protein. 173 1e-42
AF263242-1|AAK58523.1| 320|Homo sapiens aldo-keto reductase loo... 173 1e-42
AB055603-1|BAC54568.1| 307|Homo sapiens aldo-keto reductase rel... 173 1e-42
AL391427-2|CAI14727.1| 302|Homo sapiens aldo-keto reductase fam... 136 3e-31
AL355303-1|CAI14201.1| 302|Homo sapiens aldo-keto reductase fam... 136 3e-31
AK058142-1|BAB71682.1| 146|Homo sapiens protein ( Homo sapiens ... 110 2e-23
AB040821-1|BAC54566.1| 263|Homo sapiens aldo-keto reductase rel... 106 2e-22
AB040820-1|BAC54565.1| 250|Homo sapiens aldo-keto reductase rel... 106 2e-22
AL355480-2|CAI22458.1| 147|Homo sapiens aldo-keto reductase fam... 94 1e-18
AB040822-1|BAC54567.1| 222|Homo sapiens aldo-keto reductase rel... 64 1e-09
AB037902-1|BAA92887.1| 130|Homo sapiens truncated aldo-keto red... 62 4e-09
AB028065-1|BAA88489.1| 67|Homo sapiens prostaglandin F synthas... 61 9e-09
BC101205-1|AAI01206.1| 129|Homo sapiens aldo-keto reductase fam... 58 1e-07
BC101204-1|AAI01205.1| 129|Homo sapiens aldo-keto reductase fam... 58 1e-07
AK131335-1|BAD18494.1| 129|Homo sapiens protein ( Homo sapiens ... 58 1e-07
AB037905-2|BAA92890.1| 45|Homo sapiens truncated aldo-keto red... 48 7e-05
AF044961-1|AAC15671.1| 85|Homo sapiens aldose reductase-relate... 40 0.024
L35546-1|AAA65028.1| 274|Homo sapiens gamma-glutamylcysteine sy... 34 1.6
CR541833-1|CAG46632.1| 274|Homo sapiens GCLM protein. 34 1.6
BC041809-1|AAH41809.1| 274|Homo sapiens glutamate-cysteine liga... 34 1.6
AY773965-1|AAV28733.1| 274|Homo sapiens glutamate-cysteine liga... 34 1.6
AL117351-10|CAI22976.1| 274|Homo sapiens glutamate-cysteine lig... 34 1.6
AL049796-2|CAI21813.1| 274|Homo sapiens glutamate-cysteine liga... 34 1.6
AK025955-1|BAB15295.1| 458|Homo sapiens protein ( Homo sapiens ... 33 2.1
AK022743-1|BAB14218.1| 567|Homo sapiens protein ( Homo sapiens ... 33 2.1
AE006465-5|AAK61259.1| 567|Homo sapiens possible integral membr... 33 2.1
AB075873-1|BAD38655.1| 563|Homo sapiens putative protein produc... 33 2.1
BC010738-1|AAH10738.2| 490|Homo sapiens TMEM112 protein protein. 33 2.8
>U37100-1|AAC17469.1| 316|Homo sapiens aldose reductase-like
peptide protein.
Length = 316
Score = 235 bits (575), Expect = 3e-61
Identities = 109/195 (55%), Positives = 139/195 (71%), Gaps = 2/195 (1%)
Frame = +2
Query: 152 KREDLFITSKLWNTFHRPDLXRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTDAD 331
KREDLFI SKLW TF L R A E +L++L + YLD+YLIHWPQ +K D +FP D
Sbjct: 69 KREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGDDLFPKDDK 128
Query: 332 GKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVK--PVTNQVECH 505
G ++D W+A+E LV GLV++LGVSNF+ Q++++L+ +K PVTNQVECH
Sbjct: 129 GNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKPVTNQVECH 188
Query: 506 PXLNQKRLKQFCEDRDIMITAYSPLGSPDRPWAKPGDPQLMEDPKLKEIADRLGKTVAQV 685
P L Q++L Q+C + I +TAYSPLGSPDRPWAKP DP L+EDPK+KEIA + KT AQV
Sbjct: 189 PYLTQEKLIQYCHSKGITVTAYSPLGSPDRPWAKPEDPSLLEDPKIKEIAAKHKKTAAQV 248
Query: 686 LIRYQIDRGNIXIPE 730
LIR+ I R I IP+
Sbjct: 249 LIRFHIQRNVIVIPK 263
Score = 39.9 bits (89), Expect = 0.024
Identities = 19/37 (51%), Positives = 23/37 (62%)
Frame = +3
Query: 726 PKSVTKSRIASNFDVFDFKLSLQDVALIDXHRLXWAA 836
PKSVT +RI N VFDFKLS +++A I W A
Sbjct: 262 PKSVTPARIVENIQVFDFKLSDEEMATILSFNRNWRA 298
>CR541801-1|CAG46600.1| 316|Homo sapiens AKR1B10 protein.
Length = 316
Score = 235 bits (575), Expect = 3e-61
Identities = 109/195 (55%), Positives = 139/195 (71%), Gaps = 2/195 (1%)
Frame = +2
Query: 152 KREDLFITSKLWNTFHRPDLXRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTDAD 331
KREDLFI SKLW TF L R A E +L++L + YLD+YLIHWPQ +K D +FP D
Sbjct: 69 KREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGDDLFPKDDK 128
Query: 332 GKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVK--PVTNQVECH 505
G ++D W+A+E LV GLV++LGVSNF+ Q++++L+ +K PVTNQVECH
Sbjct: 129 GNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKPVTNQVECH 188
Query: 506 PXLNQKRLKQFCEDRDIMITAYSPLGSPDRPWAKPGDPQLMEDPKLKEIADRLGKTVAQV 685
P L Q++L Q+C + I +TAYSPLGSPDRPWAKP DP L+EDPK+KEIA + KT AQV
Sbjct: 189 PYLTQEKLIQYCHSKGITVTAYSPLGSPDRPWAKPEDPSLLEDPKIKEIAAKHKKTAAQV 248
Query: 686 LIRYQIDRGNIXIPE 730
LIR+ I R I IP+
Sbjct: 249 LIRFHIQRNVIVIPK 263
Score = 39.9 bits (89), Expect = 0.024
Identities = 19/37 (51%), Positives = 23/37 (62%)
Frame = +3
Query: 726 PKSVTKSRIASNFDVFDFKLSLQDVALIDXHRLXWAA 836
PKSVT +RI N VFDFKLS +++A I W A
Sbjct: 262 PKSVTPARIVENIQVFDFKLSDEEMATILSFNRNWRA 298
>BT006794-1|AAP35440.1| 316|Homo sapiens aldo-keto reductase family
1, member B10 (aldose reductase) protein.
Length = 316
Score = 235 bits (575), Expect = 3e-61
Identities = 109/195 (55%), Positives = 139/195 (71%), Gaps = 2/195 (1%)
Frame = +2
Query: 152 KREDLFITSKLWNTFHRPDLXRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTDAD 331
KREDLFI SKLW TF L R A E +L++L + YLD+YLIHWPQ +K D +FP D
Sbjct: 69 KREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGDDLFPKDDK 128
Query: 332 GKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVK--PVTNQVECH 505
G ++D W+A+E LV GLV++LGVSNF+ Q++++L+ +K PVTNQVECH
Sbjct: 129 GNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKPVTNQVECH 188
Query: 506 PXLNQKRLKQFCEDRDIMITAYSPLGSPDRPWAKPGDPQLMEDPKLKEIADRLGKTVAQV 685
P L Q++L Q+C + I +TAYSPLGSPDRPWAKP DP L+EDPK+KEIA + KT AQV
Sbjct: 189 PYLTQEKLIQYCHSKGITVTAYSPLGSPDRPWAKPEDPSLLEDPKIKEIAAKHKKTAAQV 248
Query: 686 LIRYQIDRGNIXIPE 730
LIR+ I R I IP+
Sbjct: 249 LIRFHIQRNVIVIPK 263
Score = 39.9 bits (89), Expect = 0.024
Identities = 19/37 (51%), Positives = 23/37 (62%)
Frame = +3
Query: 726 PKSVTKSRIASNFDVFDFKLSLQDVALIDXHRLXWAA 836
PKSVT +RI N VFDFKLS +++A I W A
Sbjct: 262 PKSVTPARIVENIQVFDFKLSDEEMATILSFNRNWRA 298
>BC008837-1|AAH08837.1| 316|Homo sapiens aldo-keto reductase family
1, member B10 (aldose reductase) protein.
Length = 316
Score = 235 bits (575), Expect = 3e-61
Identities = 109/195 (55%), Positives = 139/195 (71%), Gaps = 2/195 (1%)
Frame = +2
Query: 152 KREDLFITSKLWNTFHRPDLXRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTDAD 331
KREDLFI SKLW TF L R A E +L++L + YLD+YLIHWPQ +K D +FP D
Sbjct: 69 KREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGDDLFPKDDK 128
Query: 332 GKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVK--PVTNQVECH 505
G ++D W+A+E LV GLV++LGVSNF+ Q++++L+ +K PVTNQVECH
Sbjct: 129 GNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKPVTNQVECH 188
Query: 506 PXLNQKRLKQFCEDRDIMITAYSPLGSPDRPWAKPGDPQLMEDPKLKEIADRLGKTVAQV 685
P L Q++L Q+C + I +TAYSPLGSPDRPWAKP DP L+EDPK+KEIA + KT AQV
Sbjct: 189 PYLTQEKLIQYCHSKGITVTAYSPLGSPDRPWAKPEDPSLLEDPKIKEIAAKHKKTAAQV 248
Query: 686 LIRYQIDRGNIXIPE 730
LIR+ I R I IP+
Sbjct: 249 LIRFHIQRNVIVIPK 263
Score = 39.9 bits (89), Expect = 0.024
Identities = 19/37 (51%), Positives = 23/37 (62%)
Frame = +3
Query: 726 PKSVTKSRIASNFDVFDFKLSLQDVALIDXHRLXWAA 836
PKSVT +RI N VFDFKLS +++A I W A
Sbjct: 262 PKSVTPARIVENIQVFDFKLSDEEMATILSFNRNWRA 298
>AF052577-1|AAC36465.1| 316|Homo sapiens aldo-keto reductase
protein.
Length = 316
Score = 235 bits (575), Expect = 3e-61
Identities = 109/195 (55%), Positives = 139/195 (71%), Gaps = 2/195 (1%)
Frame = +2
Query: 152 KREDLFITSKLWNTFHRPDLXRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTDAD 331
KREDLFI SKLW TF L R A E +L++L + YLD+YLIHWPQ +K D +FP D
Sbjct: 69 KREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGDDLFPKDDK 128
Query: 332 GKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVK--PVTNQVECH 505
G ++D W+A+E LV GLV++LGVSNF+ Q++++L+ +K PVTNQVECH
Sbjct: 129 GNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKPVTNQVECH 188
Query: 506 PXLNQKRLKQFCEDRDIMITAYSPLGSPDRPWAKPGDPQLMEDPKLKEIADRLGKTVAQV 685
P L Q++L Q+C + I +TAYSPLGSPDRPWAKP DP L+EDPK+KEIA + KT AQV
Sbjct: 189 PYLTQEKLIQYCHSKGITVTAYSPLGSPDRPWAKPEDPSLLEDPKIKEIAAKHKKTAAQV 248
Query: 686 LIRYQIDRGNIXIPE 730
LIR+ I R I IP+
Sbjct: 249 LIRFHIQRNVIVIPK 263
Score = 39.9 bits (89), Expect = 0.024
Identities = 19/37 (51%), Positives = 23/37 (62%)
Frame = +3
Query: 726 PKSVTKSRIASNFDVFDFKLSLQDVALIDXHRLXWAA 836
PKSVT +RI N VFDFKLS +++A I W A
Sbjct: 262 PKSVTPARIVENIQVFDFKLSDEEMATILSFNRNWRA 298
>X15414-1|CAA33460.1| 316|Homo sapiens protein ( Human mRNA for
aldose reductase (EC 1.1.1.2). ).
Length = 316
Score = 233 bits (570), Expect = 1e-60
Identities = 103/195 (52%), Positives = 139/195 (71%), Gaps = 2/195 (1%)
Frame = +2
Query: 152 KREDLFITSKLWNTFHRPDLXRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTDAD 331
KRE+LFI SKLW T+H L +GA + +L +L +DYLDLYLIHWP +K FP D
Sbjct: 69 KREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFPLDES 128
Query: 332 GKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASV--KPVTNQVECH 505
G + SD + +DTW A+E LV GLV+++G+SNFN Q++ IL+ + KP NQ+ECH
Sbjct: 129 GNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQIECH 188
Query: 506 PXLNQKRLKQFCEDRDIMITAYSPLGSPDRPWAKPGDPQLMEDPKLKEIADRLGKTVAQV 685
P L Q++L Q+C+ + I++TAYSPLGSPDRPWAKP DP L+EDP++K IA + KT AQV
Sbjct: 189 PYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAKHNKTTAQV 248
Query: 686 LIRYQIDRGNIXIPE 730
LIR+ + R + IP+
Sbjct: 249 LIRFPMQRNLVVIPK 263
Score = 42.7 bits (96), Expect = 0.003
Identities = 19/35 (54%), Positives = 23/35 (65%)
Frame = +3
Query: 726 PKSVTKSRIASNFDVFDFKLSLQDVALIDXHRLXW 830
PKSVT RIA NF VFDF+LS QD+ + + W
Sbjct: 262 PKSVTPERIAENFKVFDFELSSQDMTTLLSYNRNW 296
>M59783-1|AAA51712.1| 316|Homo sapiens aldose reductase protein.
Length = 316
Score = 233 bits (570), Expect = 1e-60
Identities = 103/195 (52%), Positives = 139/195 (71%), Gaps = 2/195 (1%)
Frame = +2
Query: 152 KREDLFITSKLWNTFHRPDLXRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTDAD 331
KRE+LFI SKLW T+H L +GA + +L +L +DYLDLYLIHWP +K FP D
Sbjct: 69 KREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFPLDES 128
Query: 332 GKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASV--KPVTNQVECH 505
G + SD + +DTW A+E LV GLV+++G+SNFN Q++ IL+ + KP NQ+ECH
Sbjct: 129 GNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQIECH 188
Query: 506 PXLNQKRLKQFCEDRDIMITAYSPLGSPDRPWAKPGDPQLMEDPKLKEIADRLGKTVAQV 685
P L Q++L Q+C+ + I++TAYSPLGSPDRPWAKP DP L+EDP++K IA + KT AQV
Sbjct: 189 PYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAKHNKTTAQV 248
Query: 686 LIRYQIDRGNIXIPE 730
LIR+ + R + IP+
Sbjct: 249 LIRFPMQRNLVVIPK 263
Score = 42.7 bits (96), Expect = 0.003
Identities = 19/35 (54%), Positives = 23/35 (65%)
Frame = +3
Query: 726 PKSVTKSRIASNFDVFDFKLSLQDVALIDXHRLXW 830
PKSVT RIA NF VFDF+LS QD+ + + W
Sbjct: 262 PKSVTPERIAENFKVFDFELSSQDMTTLLSYNRNW 296
>M34720-1|AAA35560.1| 316|Homo sapiens protein ( Human aldose
reductase mRNA, complete cds. ).
Length = 316
Score = 233 bits (570), Expect = 1e-60
Identities = 103/195 (52%), Positives = 139/195 (71%), Gaps = 2/195 (1%)
Frame = +2
Query: 152 KREDLFITSKLWNTFHRPDLXRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTDAD 331
KRE+LFI SKLW T+H L +GA + +L +L +DYLDLYLIHWP +K FP D
Sbjct: 69 KREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFPLDES 128
Query: 332 GKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASV--KPVTNQVECH 505
G + SD + +DTW A+E LV GLV+++G+SNFN Q++ IL+ + KP NQ+ECH
Sbjct: 129 GNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQIECH 188
Query: 506 PXLNQKRLKQFCEDRDIMITAYSPLGSPDRPWAKPGDPQLMEDPKLKEIADRLGKTVAQV 685
P L Q++L Q+C+ + I++TAYSPLGSPDRPWAKP DP L+EDP++K IA + KT AQV
Sbjct: 189 PYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAKHNKTTAQV 248
Query: 686 LIRYQIDRGNIXIPE 730
LIR+ + R + IP+
Sbjct: 249 LIRFPMQRNLVVIPK 263
Score = 42.7 bits (96), Expect = 0.003
Identities = 19/35 (54%), Positives = 23/35 (65%)
Frame = +3
Query: 726 PKSVTKSRIASNFDVFDFKLSLQDVALIDXHRLXW 830
PKSVT RIA NF VFDF+LS QD+ + + W
Sbjct: 262 PKSVTPERIAENFKVFDFELSSQDMTTLLSYNRNW 296
>J05474-1|AAA51715.1| 316|Homo sapiens aldose reductase protein.
Length = 316
Score = 233 bits (570), Expect = 1e-60
Identities = 103/195 (52%), Positives = 139/195 (71%), Gaps = 2/195 (1%)
Frame = +2
Query: 152 KREDLFITSKLWNTFHRPDLXRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTDAD 331
KRE+LFI SKLW T+H L +GA + +L +L +DYLDLYLIHWP +K FP D
Sbjct: 69 KREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFPLDES 128
Query: 332 GKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASV--KPVTNQVECH 505
G + SD + +DTW A+E LV GLV+++G+SNFN Q++ IL+ + KP NQ+ECH
Sbjct: 129 GNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQIECH 188
Query: 506 PXLNQKRLKQFCEDRDIMITAYSPLGSPDRPWAKPGDPQLMEDPKLKEIADRLGKTVAQV 685
P L Q++L Q+C+ + I++TAYSPLGSPDRPWAKP DP L+EDP++K IA + KT AQV
Sbjct: 189 PYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAKHNKTTAQV 248
Query: 686 LIRYQIDRGNIXIPE 730
LIR+ + R + IP+
Sbjct: 249 LIRFPMQRNLVVIPK 263
Score = 42.7 bits (96), Expect = 0.003
Identities = 19/35 (54%), Positives = 23/35 (65%)
Frame = +3
Query: 726 PKSVTKSRIASNFDVFDFKLSLQDVALIDXHRLXW 830
PKSVT RIA NF VFDF+LS QD+ + + W
Sbjct: 262 PKSVTPERIAENFKVFDFELSSQDMTTLLSYNRNW 296
>J05017-1|AAA51714.1| 316|Homo sapiens ALDR1 protein.
Length = 316
Score = 233 bits (570), Expect = 1e-60
Identities = 103/195 (52%), Positives = 139/195 (71%), Gaps = 2/195 (1%)
Frame = +2
Query: 152 KREDLFITSKLWNTFHRPDLXRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTDAD 331
KRE+LFI SKLW T+H L +GA + +L +L +DYLDLYLIHWP +K FP D
Sbjct: 69 KREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFPLDES 128
Query: 332 GKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASV--KPVTNQVECH 505
G + SD + +DTW A+E LV GLV+++G+SNFN Q++ IL+ + KP NQ+ECH
Sbjct: 129 GNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQIECH 188
Query: 506 PXLNQKRLKQFCEDRDIMITAYSPLGSPDRPWAKPGDPQLMEDPKLKEIADRLGKTVAQV 685
P L Q++L Q+C+ + I++TAYSPLGSPDRPWAKP DP L+EDP++K IA + KT AQV
Sbjct: 189 PYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAKHNKTTAQV 248
Query: 686 LIRYQIDRGNIXIPE 730
LIR+ + R + IP+
Sbjct: 249 LIRFPMQRNLVVIPK 263
Score = 42.7 bits (96), Expect = 0.003
Identities = 19/35 (54%), Positives = 23/35 (65%)
Frame = +3
Query: 726 PKSVTKSRIASNFDVFDFKLSLQDVALIDXHRLXW 830
PKSVT RIA NF VFDF+LS QD+ + + W
Sbjct: 262 PKSVTPERIAENFKVFDFELSSQDMTTLLSYNRNW 296
>J04795-1|AAA51713.1| 316|Homo sapiens ALDR1 protein.
Length = 316
Score = 233 bits (570), Expect = 1e-60
Identities = 103/195 (52%), Positives = 139/195 (71%), Gaps = 2/195 (1%)
Frame = +2
Query: 152 KREDLFITSKLWNTFHRPDLXRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTDAD 331
KRE+LFI SKLW T+H L +GA + +L +L +DYLDLYLIHWP +K FP D
Sbjct: 69 KREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFPLDES 128
Query: 332 GKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASV--KPVTNQVECH 505
G + SD + +DTW A+E LV GLV+++G+SNFN Q++ IL+ + KP NQ+ECH
Sbjct: 129 GNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQIECH 188
Query: 506 PXLNQKRLKQFCEDRDIMITAYSPLGSPDRPWAKPGDPQLMEDPKLKEIADRLGKTVAQV 685
P L Q++L Q+C+ + I++TAYSPLGSPDRPWAKP DP L+EDP++K IA + KT AQV
Sbjct: 189 PYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAKHNKTTAQV 248
Query: 686 LIRYQIDRGNIXIPE 730
LIR+ + R + IP+
Sbjct: 249 LIRFPMQRNLVVIPK 263
Score = 42.7 bits (96), Expect = 0.003
Identities = 19/35 (54%), Positives = 23/35 (65%)
Frame = +3
Query: 726 PKSVTKSRIASNFDVFDFKLSLQDVALIDXHRLXW 830
PKSVT RIA NF VFDF+LS QD+ + + W
Sbjct: 262 PKSVTPERIAENFKVFDFELSSQDMTTLLSYNRNW 296
>BT019859-1|AAV38662.1| 316|Homo sapiens aldo-keto reductase family
1, member B1 (aldose reductase) protein.
Length = 316
Score = 233 bits (570), Expect = 1e-60
Identities = 103/195 (52%), Positives = 139/195 (71%), Gaps = 2/195 (1%)
Frame = +2
Query: 152 KREDLFITSKLWNTFHRPDLXRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTDAD 331
KRE+LFI SKLW T+H L +GA + +L +L +DYLDLYLIHWP +K FP D
Sbjct: 69 KREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFPLDES 128
Query: 332 GKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASV--KPVTNQVECH 505
G + SD + +DTW A+E LV GLV+++G+SNFN Q++ IL+ + KP NQ+ECH
Sbjct: 129 GNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQIECH 188
Query: 506 PXLNQKRLKQFCEDRDIMITAYSPLGSPDRPWAKPGDPQLMEDPKLKEIADRLGKTVAQV 685
P L Q++L Q+C+ + I++TAYSPLGSPDRPWAKP DP L+EDP++K IA + KT AQV
Sbjct: 189 PYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAKHNKTTAQV 248
Query: 686 LIRYQIDRGNIXIPE 730
LIR+ + R + IP+
Sbjct: 249 LIRFPMQRNLVVIPK 263
Score = 42.7 bits (96), Expect = 0.003
Identities = 19/35 (54%), Positives = 23/35 (65%)
Frame = +3
Query: 726 PKSVTKSRIASNFDVFDFKLSLQDVALIDXHRLXW 830
PKSVT RIA NF VFDF+LS QD+ + + W
Sbjct: 262 PKSVTPERIAENFKVFDFELSSQDMTTLLSYNRNW 296
>BC010391-1|AAH10391.1| 316|Homo sapiens aldo-keto reductase family
1, member B1 (aldose reductase) protein.
Length = 316
Score = 233 bits (570), Expect = 1e-60
Identities = 103/195 (52%), Positives = 139/195 (71%), Gaps = 2/195 (1%)
Frame = +2
Query: 152 KREDLFITSKLWNTFHRPDLXRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTDAD 331
KRE+LFI SKLW T+H L +GA + +L +L +DYLDLYLIHWP +K FP D
Sbjct: 69 KREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFPLDES 128
Query: 332 GKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASV--KPVTNQVECH 505
G + SD + +DTW A+E LV GLV+++G+SNFN Q++ IL+ + KP NQ+ECH
Sbjct: 129 GNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQIECH 188
Query: 506 PXLNQKRLKQFCEDRDIMITAYSPLGSPDRPWAKPGDPQLMEDPKLKEIADRLGKTVAQV 685
P L Q++L Q+C+ + I++TAYSPLGSPDRPWAKP DP L+EDP++K IA + KT AQV
Sbjct: 189 PYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAKHNKTTAQV 248
Query: 686 LIRYQIDRGNIXIPE 730
LIR+ + R + IP+
Sbjct: 249 LIRFPMQRNLVVIPK 263
Score = 42.7 bits (96), Expect = 0.003
Identities = 19/35 (54%), Positives = 23/35 (65%)
Frame = +3
Query: 726 PKSVTKSRIASNFDVFDFKLSLQDVALIDXHRLXW 830
PKSVT RIA NF VFDF+LS QD+ + + W
Sbjct: 262 PKSVTPERIAENFKVFDFELSSQDMTTLLSYNRNW 296
>BC000260-1|AAH00260.1| 316|Homo sapiens aldo-keto reductase family
1, member B1 (aldose reductase) protein.
Length = 316
Score = 233 bits (570), Expect = 1e-60
Identities = 103/195 (52%), Positives = 139/195 (71%), Gaps = 2/195 (1%)
Frame = +2
Query: 152 KREDLFITSKLWNTFHRPDLXRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTDAD 331
KRE+LFI SKLW T+H L +GA + +L +L +DYLDLYLIHWP +K FP D
Sbjct: 69 KREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFPLDES 128
Query: 332 GKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASV--KPVTNQVECH 505
G + SD + +DTW A+E LV GLV+++G+SNFN Q++ IL+ + KP NQ+ECH
Sbjct: 129 GNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQIECH 188
Query: 506 PXLNQKRLKQFCEDRDIMITAYSPLGSPDRPWAKPGDPQLMEDPKLKEIADRLGKTVAQV 685
P L Q++L Q+C+ + I++TAYSPLGSPDRPWAKP DP L+EDP++K IA + KT AQV
Sbjct: 189 PYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAKHNKTTAQV 248
Query: 686 LIRYQIDRGNIXIPE 730
LIR+ + R + IP+
Sbjct: 249 LIRFPMQRNLVVIPK 263
Score = 42.7 bits (96), Expect = 0.003
Identities = 19/35 (54%), Positives = 23/35 (65%)
Frame = +3
Query: 726 PKSVTKSRIASNFDVFDFKLSLQDVALIDXHRLXW 830
PKSVT RIA NF VFDF+LS QD+ + + W
Sbjct: 262 PKSVTPERIAENFKVFDFELSSQDMTTLLSYNRNW 296
>AF328729-1|AAN09721.1| 316|Homo sapiens CTCL tumor antigen
HD-CL-07 protein.
Length = 316
Score = 233 bits (570), Expect = 1e-60
Identities = 103/195 (52%), Positives = 139/195 (71%), Gaps = 2/195 (1%)
Frame = +2
Query: 152 KREDLFITSKLWNTFHRPDLXRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTDAD 331
KRE+LFI SKLW T+H L +GA + +L +L +DYLDLYLIHWP +K FP D
Sbjct: 69 KREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFPLDES 128
Query: 332 GKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASV--KPVTNQVECH 505
G + SD + +DTW A+E LV GLV+++G+SNFN Q++ IL+ + KP NQ+ECH
Sbjct: 129 GNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQIECH 188
Query: 506 PXLNQKRLKQFCEDRDIMITAYSPLGSPDRPWAKPGDPQLMEDPKLKEIADRLGKTVAQV 685
P L Q++L Q+C+ + I++TAYSPLGSPDRPWAKP DP L+EDP++K IA + KT AQV
Sbjct: 189 PYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAKHNKTTAQV 248
Query: 686 LIRYQIDRGNIXIPE 730
LIR+ + R + IP+
Sbjct: 249 LIRFPMQRNLVVIPK 263
Score = 42.7 bits (96), Expect = 0.003
Identities = 19/35 (54%), Positives = 23/35 (65%)
Frame = +3
Query: 726 PKSVTKSRIASNFDVFDFKLSLQDVALIDXHRLXW 830
PKSVT RIA NF VFDF+LS QD+ + + W
Sbjct: 262 PKSVTPERIAENFKVFDFELSSQDMTTLLSYNRNW 296
>AF032455-1|AAB88851.1| 316|Homo sapiens aldose reductase protein.
Length = 316
Score = 233 bits (570), Expect = 1e-60
Identities = 103/195 (52%), Positives = 139/195 (71%), Gaps = 2/195 (1%)
Frame = +2
Query: 152 KREDLFITSKLWNTFHRPDLXRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTDAD 331
KRE+LFI SKLW T+H L +GA + +L +L +DYLDLYLIHWP +K FP D
Sbjct: 69 KREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFPLDES 128
Query: 332 GKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASV--KPVTNQVECH 505
G + SD + +DTW A+E LV GLV+++G+SNFN Q++ IL+ + KP NQ+ECH
Sbjct: 129 GNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQIECH 188
Query: 506 PXLNQKRLKQFCEDRDIMITAYSPLGSPDRPWAKPGDPQLMEDPKLKEIADRLGKTVAQV 685
P L Q++L Q+C+ + I++TAYSPLGSPDRPWAKP DP L+EDP++K IA + KT AQV
Sbjct: 189 PYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAKHNKTTAQV 248
Query: 686 LIRYQIDRGNIXIPE 730
LIR+ + R + IP+
Sbjct: 249 LIRFPMQRNLVVIPK 263
Score = 42.7 bits (96), Expect = 0.003
Identities = 19/35 (54%), Positives = 23/35 (65%)
Frame = +3
Query: 726 PKSVTKSRIASNFDVFDFKLSLQDVALIDXHRLXW 830
PKSVT RIA NF VFDF+LS QD+ + + W
Sbjct: 262 PKSVTPERIAENFKVFDFELSSQDMTTLLSYNRNW 296
>CR542203-1|CAG47000.1| 316|Homo sapiens AKR1B1 protein.
Length = 316
Score = 232 bits (568), Expect = 2e-60
Identities = 103/195 (52%), Positives = 139/195 (71%), Gaps = 2/195 (1%)
Frame = +2
Query: 152 KREDLFITSKLWNTFHRPDLXRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTDAD 331
KRE+LFI SKLW T+H L +GA + +L +L +DYLDLYLIHWP +K FP D
Sbjct: 69 KREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPIGFKPGKEFFPLDES 128
Query: 332 GKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASV--KPVTNQVECH 505
G + SD + +DTW A+E LV GLV+++G+SNFN Q++ IL+ + KP NQ+ECH
Sbjct: 129 GNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQIECH 188
Query: 506 PXLNQKRLKQFCEDRDIMITAYSPLGSPDRPWAKPGDPQLMEDPKLKEIADRLGKTVAQV 685
P L Q++L Q+C+ + I++TAYSPLGSPDRPWAKP DP L+EDP++K IA + KT AQV
Sbjct: 189 PYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAKHNKTTAQV 248
Query: 686 LIRYQIDRGNIXIPE 730
LIR+ + R + IP+
Sbjct: 249 LIRFPMQRNLVVIPK 263
Score = 42.7 bits (96), Expect = 0.003
Identities = 19/35 (54%), Positives = 23/35 (65%)
Frame = +3
Query: 726 PKSVTKSRIASNFDVFDFKLSLQDVALIDXHRLXW 830
PKSVT RIA NF VFDF+LS QD+ + + W
Sbjct: 262 PKSVTPERIAENFKVFDFELSSQDMTTLLSYNRNW 296
>AF524864-1|AAO13380.1| 316|Homo sapiens aldo-ketoreductase
protein.
Length = 316
Score = 232 bits (568), Expect = 2e-60
Identities = 108/195 (55%), Positives = 138/195 (70%), Gaps = 2/195 (1%)
Frame = +2
Query: 152 KREDLFITSKLWNTFHRPDLXRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTDAD 331
KREDLFI SKLW TF L R A E +L++ + YLD+YLIHWPQ +K D +FP D
Sbjct: 69 KREDLFIASKLWPTFFERPLVRKAFEKTLKDPKLSYLDVYLIHWPQGFKSGDDLFPKDDK 128
Query: 332 GKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVK--PVTNQVECH 505
G ++D W+A+E LV GLV++LGVSNF+ Q++++L+ +K PVTNQVECH
Sbjct: 129 GNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKPVTNQVECH 188
Query: 506 PXLNQKRLKQFCEDRDIMITAYSPLGSPDRPWAKPGDPQLMEDPKLKEIADRLGKTVAQV 685
P L Q++L Q+C + I +TAYSPLGSPDRPWAKP DP L+EDPK+KEIA + KT AQV
Sbjct: 189 PYLTQEKLIQYCHSKGITVTAYSPLGSPDRPWAKPEDPSLLEDPKIKEIAAKHKKTAAQV 248
Query: 686 LIRYQIDRGNIXIPE 730
LIR+ I R I IP+
Sbjct: 249 LIRFHIQRNVIVIPK 263
Score = 41.1 bits (92), Expect = 0.010
Identities = 19/37 (51%), Positives = 24/37 (64%)
Frame = +3
Query: 726 PKSVTKSRIASNFDVFDFKLSLQDVALIDXHRLXWAA 836
PKSVT +RI N VFDFKLS +++A+I W A
Sbjct: 262 PKSVTPARIVENIQVFDFKLSDEEMAIILSFNRNWRA 298
>CR450351-1|CAG29347.1| 316|Homo sapiens AKR1B1 protein.
Length = 316
Score = 231 bits (566), Expect = 4e-60
Identities = 102/195 (52%), Positives = 138/195 (70%), Gaps = 2/195 (1%)
Frame = +2
Query: 152 KREDLFITSKLWNTFHRPDLXRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTDAD 331
KRE+LFI SKLW T+H L +GA + +L +L +DYLDLYLIHWP ++ FP D
Sbjct: 69 KREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFRPGKEFFPLDES 128
Query: 332 GKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASV--KPVTNQVECH 505
G + SD + +DTW A+E LV GLV+++G+SNFN Q++ IL + KP NQ+ECH
Sbjct: 129 GNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILSKPGLKYKPAVNQIECH 188
Query: 506 PXLNQKRLKQFCEDRDIMITAYSPLGSPDRPWAKPGDPQLMEDPKLKEIADRLGKTVAQV 685
P L Q++L Q+C+ + I++TAYSPLGSPDRPWAKP DP L+EDP++K IA + KT AQV
Sbjct: 189 PYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAKHNKTTAQV 248
Query: 686 LIRYQIDRGNIXIPE 730
LIR+ + R + IP+
Sbjct: 249 LIRFPMQRNLVVIPK 263
Score = 42.7 bits (96), Expect = 0.003
Identities = 19/35 (54%), Positives = 23/35 (65%)
Frame = +3
Query: 726 PKSVTKSRIASNFDVFDFKLSLQDVALIDXHRLXW 830
PKSVT RIA NF VFDF+LS QD+ + + W
Sbjct: 262 PKSVTPERIAENFKVFDFELSSQDMTTLLSYNRNW 296
>BC005387-1|AAH05387.1| 316|Homo sapiens aldo-keto reductase family
1, member B1 (aldose reductase) protein.
Length = 316
Score = 227 bits (556), Expect = 6e-59
Identities = 102/195 (52%), Positives = 138/195 (70%), Gaps = 2/195 (1%)
Frame = +2
Query: 152 KREDLFITSKLWNTFHRPDLXRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTDAD 331
KRE+LFI SKLW T+H L +GA + +L +L +DYLDLYLIHWP +K FP D
Sbjct: 69 KREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFPLDES 128
Query: 332 GKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVK--PVTNQVECH 505
G + SD + +DT A+E LV GLV+++G+SNFN Q++ IL+ +K P NQ+ECH
Sbjct: 129 GNVVPSDTNILDTRAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQIECH 188
Query: 506 PXLNQKRLKQFCEDRDIMITAYSPLGSPDRPWAKPGDPQLMEDPKLKEIADRLGKTVAQV 685
P L Q++L Q+C+ + I++TAYSPLGSPDRPWAKP DP L+EDP++K IA + KT AQV
Sbjct: 189 PYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAKHNKTTAQV 248
Query: 686 LIRYQIDRGNIXIPE 730
LIR+ + R + IP+
Sbjct: 249 LIRFPMQRNLVVIPK 263
Score = 42.7 bits (96), Expect = 0.003
Identities = 19/35 (54%), Positives = 23/35 (65%)
Frame = +3
Query: 726 PKSVTKSRIASNFDVFDFKLSLQDVALIDXHRLXW 830
PKSVT RIA NF VFDF+LS QD+ + + W
Sbjct: 262 PKSVTPERIAENFKVFDFELSSQDMTTLLSYNRNW 296
>AB209796-1|BAD93033.1| 260|Homo sapiens aldo-keto reductase family
1, member B1 variant protein.
Length = 260
Score = 220 bits (538), Expect = 9e-57
Identities = 97/180 (53%), Positives = 129/180 (71%), Gaps = 2/180 (1%)
Frame = +2
Query: 152 KREDLFITSKLWNTFHRPDLXRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTDAD 331
KRE+LFI SKLW T+H L +GA + +L +L +DYLDLYLIHWP +K FP D
Sbjct: 66 KREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFPLDES 125
Query: 332 GKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASV--KPVTNQVECH 505
G + SD + +DTW A+E LV GLV+++G+SNFN Q++ IL+ + KP NQ+ECH
Sbjct: 126 GNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQIECH 185
Query: 506 PXLNQKRLKQFCEDRDIMITAYSPLGSPDRPWAKPGDPQLMEDPKLKEIADRLGKTVAQV 685
P L Q++L Q+C+ + I++TAYSPLGSPDRPWAKP DP L+EDP++K IA + KT AQV
Sbjct: 186 PYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAKHNKTTAQV 245
>J04794-1|AAA51711.1| 325|Homo sapiens ALDR1 protein.
Length = 325
Score = 216 bits (528), Expect = 2e-55
Identities = 98/192 (51%), Positives = 134/192 (69%)
Frame = +2
Query: 155 REDLFITSKLWNTFHRPDLXRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTDADG 334
RE+LF+TSKLWNT H P+ AL +L +L ++YLDLYL+HWP A++ D FP +ADG
Sbjct: 72 REELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDNPFPKNADG 131
Query: 335 KIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPVTNQVECHPXL 514
I + Y +TWKALE LV GLV++LG+SNFNS+Q+ IL ASV+P QVECHP L
Sbjct: 132 TICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASVRPAVLQVECHPYL 191
Query: 515 NQKRLKQFCEDRDIMITAYSPLGSPDRPWAKPGDPQLMEDPKLKEIADRLGKTVAQVLIR 694
Q L C+ R + +TAYSPLGS DR W P +P L+E+P + +A++ G++ AQ+L+R
Sbjct: 192 AQNELIAHCQARGLEVTAYSPLGSSDRAWRDPDEPVLLEEPVVLALAEKYGRSPAQILLR 251
Query: 695 YQIDRGNIXIPE 730
+Q+ R I IP+
Sbjct: 252 WQVQRKVICIPK 263
Score = 33.1 bits (72), Expect = 2.8
Identities = 14/35 (40%), Positives = 20/35 (57%)
Frame = +3
Query: 726 PKSVTKSRIASNFDVFDFKLSLQDVALIDXHRLXW 830
PKS+T SRI N VFDF S +++ ++ W
Sbjct: 262 PKSITPSRILQNIKVFDFTFSPEEMKQLNALNKNW 296
>CR457010-1|CAG33291.1| 325|Homo sapiens AKR1A1 protein.
Length = 325
Score = 216 bits (528), Expect = 2e-55
Identities = 98/192 (51%), Positives = 134/192 (69%)
Frame = +2
Query: 155 REDLFITSKLWNTFHRPDLXRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTDADG 334
RE+LF+TSKLWNT H P+ AL +L +L ++YLDLYL+HWP A++ D FP +ADG
Sbjct: 72 REELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDNPFPKNADG 131
Query: 335 KIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPVTNQVECHPXL 514
I + Y +TWKALE LV GLV++LG+SNFNS+Q+ IL ASV+P QVECHP L
Sbjct: 132 TICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASVRPAVLQVECHPYL 191
Query: 515 NQKRLKQFCEDRDIMITAYSPLGSPDRPWAKPGDPQLMEDPKLKEIADRLGKTVAQVLIR 694
Q L C+ R + +TAYSPLGS DR W P +P L+E+P + +A++ G++ AQ+L+R
Sbjct: 192 AQNELIAHCQARGLEVTAYSPLGSSDRAWRDPDEPVLLEEPVVLALAEKYGRSPAQILLR 251
Query: 695 YQIDRGNIXIPE 730
+Q+ R I IP+
Sbjct: 252 WQVQRKVICIPK 263
Score = 33.1 bits (72), Expect = 2.8
Identities = 14/35 (40%), Positives = 20/35 (57%)
Frame = +3
Query: 726 PKSVTKSRIASNFDVFDFKLSLQDVALIDXHRLXW 830
PKS+T SRI N VFDF S +++ ++ W
Sbjct: 262 PKSITPSRILQNIKVFDFTFSPEEMKQLNALNKNW 296
>BT007003-1|AAP35649.1| 325|Homo sapiens aldo-keto reductase family
1, member A1 (aldehyde reductase) protein.
Length = 325
Score = 216 bits (528), Expect = 2e-55
Identities = 98/192 (51%), Positives = 134/192 (69%)
Frame = +2
Query: 155 REDLFITSKLWNTFHRPDLXRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTDADG 334
RE+LF+TSKLWNT H P+ AL +L +L ++YLDLYL+HWP A++ D FP +ADG
Sbjct: 72 REELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDNPFPKNADG 131
Query: 335 KIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPVTNQVECHPXL 514
I + Y +TWKALE LV GLV++LG+SNFNS+Q+ IL ASV+P QVECHP L
Sbjct: 132 TICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASVRPAVLQVECHPYL 191
Query: 515 NQKRLKQFCEDRDIMITAYSPLGSPDRPWAKPGDPQLMEDPKLKEIADRLGKTVAQVLIR 694
Q L C+ R + +TAYSPLGS DR W P +P L+E+P + +A++ G++ AQ+L+R
Sbjct: 192 AQNELIAHCQARGLEVTAYSPLGSSDRAWRDPDEPVLLEEPVVLALAEKYGRSPAQILLR 251
Query: 695 YQIDRGNIXIPE 730
+Q+ R I IP+
Sbjct: 252 WQVQRKVICIPK 263
Score = 33.1 bits (72), Expect = 2.8
Identities = 14/35 (40%), Positives = 20/35 (57%)
Frame = +3
Query: 726 PKSVTKSRIASNFDVFDFKLSLQDVALIDXHRLXW 830
PKS+T SRI N VFDF S +++ ++ W
Sbjct: 262 PKSITPSRILQNIKVFDFTFSPEEMKQLNALNKNW 296
>BC005394-1|AAH05394.1| 325|Homo sapiens aldo-keto reductase family
1, member A1 (aldehyde reductase) protein.
Length = 325
Score = 216 bits (528), Expect = 2e-55
Identities = 98/192 (51%), Positives = 134/192 (69%)
Frame = +2
Query: 155 REDLFITSKLWNTFHRPDLXRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTDADG 334
RE+LF+TSKLWNT H P+ AL +L +L ++YLDLYL+HWP A++ D FP +ADG
Sbjct: 72 REELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDNPFPKNADG 131
Query: 335 KIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPVTNQVECHPXL 514
I + Y +TWKALE LV GLV++LG+SNFNS+Q+ IL ASV+P QVECHP L
Sbjct: 132 TICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASVRPAVLQVECHPYL 191
Query: 515 NQKRLKQFCEDRDIMITAYSPLGSPDRPWAKPGDPQLMEDPKLKEIADRLGKTVAQVLIR 694
Q L C+ R + +TAYSPLGS DR W P +P L+E+P + +A++ G++ AQ+L+R
Sbjct: 192 AQNELIAHCQARGLEVTAYSPLGSSDRAWRDPDEPVLLEEPVVLALAEKYGRSPAQILLR 251
Query: 695 YQIDRGNIXIPE 730
+Q+ R I IP+
Sbjct: 252 WQVQRKVICIPK 263
Score = 33.1 bits (72), Expect = 2.8
Identities = 14/35 (40%), Positives = 20/35 (57%)
Frame = +3
Query: 726 PKSVTKSRIASNFDVFDFKLSLQDVALIDXHRLXW 830
PKS+T SRI N VFDF S +++ ++ W
Sbjct: 262 PKSITPSRILQNIKVFDFTFSPEEMKQLNALNKNW 296
>BC000670-1|AAH00670.1| 325|Homo sapiens aldo-keto reductase family
1, member A1 (aldehyde reductase) protein.
Length = 325
Score = 216 bits (528), Expect = 2e-55
Identities = 98/192 (51%), Positives = 134/192 (69%)
Frame = +2
Query: 155 REDLFITSKLWNTFHRPDLXRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTDADG 334
RE+LF+TSKLWNT H P+ AL +L +L ++YLDLYL+HWP A++ D FP +ADG
Sbjct: 72 REELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDNPFPKNADG 131
Query: 335 KIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPVTNQVECHPXL 514
I + Y +TWKALE LV GLV++LG+SNFNS+Q+ IL ASV+P QVECHP L
Sbjct: 132 TICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASVRPAVLQVECHPYL 191
Query: 515 NQKRLKQFCEDRDIMITAYSPLGSPDRPWAKPGDPQLMEDPKLKEIADRLGKTVAQVLIR 694
Q L C+ R + +TAYSPLGS DR W P +P L+E+P + +A++ G++ AQ+L+R
Sbjct: 192 AQNELIAHCQARGLEVTAYSPLGSSDRAWRDPDEPVLLEEPVVLALAEKYGRSPAQILLR 251
Query: 695 YQIDRGNIXIPE 730
+Q+ R I IP+
Sbjct: 252 WQVQRKVICIPK 263
Score = 33.1 bits (72), Expect = 2.8
Identities = 14/35 (40%), Positives = 20/35 (57%)
Frame = +3
Query: 726 PKSVTKSRIASNFDVFDFKLSLQDVALIDXHRLXW 830
PKS+T SRI N VFDF S +++ ++ W
Sbjct: 262 PKSITPSRILQNIKVFDFTFSPEEMKQLNALNKNW 296
>AL355480-3|CAI22459.1| 325|Homo sapiens aldo-keto reductase family
1, member A1 (aldehydetase, 1 protein.
Length = 325
Score = 216 bits (528), Expect = 2e-55
Identities = 98/192 (51%), Positives = 134/192 (69%)
Frame = +2
Query: 155 REDLFITSKLWNTFHRPDLXRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTDADG 334
RE+LF+TSKLWNT H P+ AL +L +L ++YLDLYL+HWP A++ D FP +ADG
Sbjct: 72 REELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDNPFPKNADG 131
Query: 335 KIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPVTNQVECHPXL 514
I + Y +TWKALE LV GLV++LG+SNFNS+Q+ IL ASV+P QVECHP L
Sbjct: 132 TICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASVRPAVLQVECHPYL 191
Query: 515 NQKRLKQFCEDRDIMITAYSPLGSPDRPWAKPGDPQLMEDPKLKEIADRLGKTVAQVLIR 694
Q L C+ R + +TAYSPLGS DR W P +P L+E+P + +A++ G++ AQ+L+R
Sbjct: 192 AQNELIAHCQARGLEVTAYSPLGSSDRAWRDPDEPVLLEEPVVLALAEKYGRSPAQILLR 251
Query: 695 YQIDRGNIXIPE 730
+Q+ R I IP+
Sbjct: 252 WQVQRKVICIPK 263
Score = 33.1 bits (72), Expect = 2.8
Identities = 14/35 (40%), Positives = 20/35 (57%)
Frame = +3
Query: 726 PKSVTKSRIASNFDVFDFKLSLQDVALIDXHRLXW 830
PKS+T SRI N VFDF S +++ ++ W
Sbjct: 262 PKSITPSRILQNIKVFDFTFSPEEMKQLNALNKNW 296
>AF112485-1|AAF01260.1| 325|Homo sapiens aldehyde reductase
protein.
Length = 325
Score = 216 bits (528), Expect = 2e-55
Identities = 98/192 (51%), Positives = 134/192 (69%)
Frame = +2
Query: 155 REDLFITSKLWNTFHRPDLXRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTDADG 334
RE+LF+TSKLWNT H P+ AL +L +L ++YLDLYL+HWP A++ D FP +ADG
Sbjct: 72 REELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDNPFPKNADG 131
Query: 335 KIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPVTNQVECHPXL 514
I + Y +TWKALE LV GLV++LG+SNFNS+Q+ IL ASV+P QVECHP L
Sbjct: 132 TICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASVRPAVLQVECHPYL 191
Query: 515 NQKRLKQFCEDRDIMITAYSPLGSPDRPWAKPGDPQLMEDPKLKEIADRLGKTVAQVLIR 694
Q L C+ R + +TAYSPLGS DR W P +P L+E+P + +A++ G++ AQ+L+R
Sbjct: 192 AQNELIAHCQARGLEVTAYSPLGSSDRAWRDPDEPVLLEEPVVLALAEKYGRSPAQILLR 251
Query: 695 YQIDRGNIXIPE 730
+Q+ R I IP+
Sbjct: 252 WQVQRKVICIPK 263
Score = 33.1 bits (72), Expect = 2.8
Identities = 14/35 (40%), Positives = 20/35 (57%)
Frame = +3
Query: 726 PKSVTKSRIASNFDVFDFKLSLQDVALIDXHRLXW 830
PKS+T SRI N VFDF S +++ ++ W
Sbjct: 262 PKSITPSRILQNIKVFDFTFSPEEMKQLNALNKNW 296
>AF036683-1|AAB92369.1| 325|Homo sapiens aldehyde reductase
protein.
Length = 325
Score = 216 bits (528), Expect = 2e-55
Identities = 98/192 (51%), Positives = 134/192 (69%)
Frame = +2
Query: 155 REDLFITSKLWNTFHRPDLXRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTDADG 334
RE+LF+TSKLWNT H P+ AL +L +L ++YLDLYL+HWP A++ D FP +ADG
Sbjct: 72 REELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDNPFPKNADG 131
Query: 335 KIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPVTNQVECHPXL 514
I + Y +TWKALE LV GLV++LG+SNFNS+Q+ IL ASV+P QVECHP L
Sbjct: 132 TICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASVRPAVLQVECHPYL 191
Query: 515 NQKRLKQFCEDRDIMITAYSPLGSPDRPWAKPGDPQLMEDPKLKEIADRLGKTVAQVLIR 694
Q L C+ R + +TAYSPLGS DR W P +P L+E+P + +A++ G++ AQ+L+R
Sbjct: 192 AQNELIAHCQARGLEVTAYSPLGSSDRAWRDPDEPVLLEEPVVLALAEKYGRSPAQILLR 251
Query: 695 YQIDRGNIXIPE 730
+Q+ R I IP+
Sbjct: 252 WQVQRKVICIPK 263
Score = 33.1 bits (72), Expect = 2.8
Identities = 14/35 (40%), Positives = 20/35 (57%)
Frame = +3
Query: 726 PKSVTKSRIASNFDVFDFKLSLQDVALIDXHRLXW 830
PKS+T SRI N VFDF S +++ ++ W
Sbjct: 262 PKSITPSRILQNIKVFDFTFSPEEMKQLNALNKNW 296
>U05861-1|AAA18115.1| 323|Homo sapiens hepatic dihydrodiol
dehydrogenase protein.
Length = 323
Score = 206 bits (504), Expect = 1e-52
Identities = 98/196 (50%), Positives = 132/196 (67%), Gaps = 3/196 (1%)
Frame = +2
Query: 146 SCKREDLFITSKLWNTFHRPDLXRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTD 325
S KRED+F TSKLW HRP+L R ALE SL+NL +DY+DLYLIH+P + K + + P D
Sbjct: 73 SVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKD 132
Query: 326 ADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASV--KPVTNQVE 499
+GKI F VD TW+A+E GL +S+GVSNFN +QL+ IL+ + KPV NQVE
Sbjct: 133 ENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVE 192
Query: 500 CHPXLNQKRLKQFCEDRDIMITAYSPLGS-PDRPWAKPGDPQLMEDPKLKEIADRLGKTV 676
CHP NQ++L FC+ +DI++ AYS LGS + PW P P L+EDP L +A + +T
Sbjct: 193 CHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTP 252
Query: 677 AQVLIRYQIDRGNIXI 724
A + +RYQ+ RG + +
Sbjct: 253 ALIALRYQLQRGVVVL 268
>U05684-1|AAA16227.1| 323|Homo sapiens dihydrodiol dehydrogenase
protein.
Length = 323
Score = 206 bits (504), Expect = 1e-52
Identities = 98/196 (50%), Positives = 132/196 (67%), Gaps = 3/196 (1%)
Frame = +2
Query: 146 SCKREDLFITSKLWNTFHRPDLXRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTD 325
S KRED+F TSKLW HRP+L R ALE SL+NL +DY+DLYLIH+P + K + + P D
Sbjct: 73 SVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKD 132
Query: 326 ADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASV--KPVTNQVE 499
+GKI F VD TW+A+E GL +S+GVSNFN +QL+ IL+ + KPV NQVE
Sbjct: 133 ENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVE 192
Query: 500 CHPXLNQKRLKQFCEDRDIMITAYSPLGS-PDRPWAKPGDPQLMEDPKLKEIADRLGKTV 676
CHP NQ++L FC+ +DI++ AYS LGS + PW P P L+EDP L +A + +T
Sbjct: 193 CHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTP 252
Query: 677 AQVLIRYQIDRGNIXI 724
A + +RYQ+ RG + +
Sbjct: 253 ALIALRYQLQRGVVVL 268
>M86609-1|AAB02880.1| 323|Homo sapiens dihydrodiol dehydrogenase
protein.
Length = 323
Score = 206 bits (504), Expect = 1e-52
Identities = 98/196 (50%), Positives = 132/196 (67%), Gaps = 3/196 (1%)
Frame = +2
Query: 146 SCKREDLFITSKLWNTFHRPDLXRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTD 325
S KRED+F TSKLW HRP+L R ALE SL+NL +DY+DLYLIH+P + K + + P D
Sbjct: 73 SVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKD 132
Query: 326 ADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASV--KPVTNQVE 499
+GKI F VD TW+A+E GL +S+GVSNFN +QL+ IL+ + KPV NQVE
Sbjct: 133 ENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVE 192
Query: 500 CHPXLNQKRLKQFCEDRDIMITAYSPLGS-PDRPWAKPGDPQLMEDPKLKEIADRLGKTV 676
CHP NQ++L FC+ +DI++ AYS LGS + PW P P L+EDP L +A + +T
Sbjct: 193 CHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTP 252
Query: 677 AQVLIRYQIDRGNIXI 724
A + +RYQ+ RG + +
Sbjct: 253 ALIALRYQLQRGVVVL 268
>D26124-1|BAA05121.1| 306|Homo sapiens dihydrodiol dehydrogenase
isoform DD1 protein.
Length = 306
Score = 206 bits (504), Expect = 1e-52
Identities = 98/196 (50%), Positives = 132/196 (67%), Gaps = 3/196 (1%)
Frame = +2
Query: 146 SCKREDLFITSKLWNTFHRPDLXRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTD 325
S KRED+F TSKLW HRP+L R ALE SL+NL +DY+DLYLIH+P + K + + P D
Sbjct: 56 SVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKD 115
Query: 326 ADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASV--KPVTNQVE 499
+GKI F VD TW+A+E GL +S+GVSNFN +QL+ IL+ + KPV NQVE
Sbjct: 116 ENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVE 175
Query: 500 CHPXLNQKRLKQFCEDRDIMITAYSPLGS-PDRPWAKPGDPQLMEDPKLKEIADRLGKTV 676
CHP NQ++L FC+ +DI++ AYS LGS + PW P P L+EDP L +A + +T
Sbjct: 176 CHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTP 235
Query: 677 AQVLIRYQIDRGNIXI 724
A + +RYQ+ RG + +
Sbjct: 236 ALIALRYQLQRGVVVL 251
>BT007197-1|AAP35861.1| 323|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 323
Score = 206 bits (504), Expect = 1e-52
Identities = 98/196 (50%), Positives = 132/196 (67%), Gaps = 3/196 (1%)
Frame = +2
Query: 146 SCKREDLFITSKLWNTFHRPDLXRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTD 325
S KRED+F TSKLW HRP+L R ALE SL+NL +DY+DLYLIH+P + K + + P D
Sbjct: 73 SVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKD 132
Query: 326 ADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASV--KPVTNQVE 499
+GKI F VD TW+A+E GL +S+GVSNFN +QL+ IL+ + KPV NQVE
Sbjct: 133 ENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVE 192
Query: 500 CHPXLNQKRLKQFCEDRDIMITAYSPLGS-PDRPWAKPGDPQLMEDPKLKEIADRLGKTV 676
CHP NQ++L FC+ +DI++ AYS LGS + PW P P L+EDP L +A + +T
Sbjct: 193 CHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTP 252
Query: 677 AQVLIRYQIDRGNIXI 724
A + +RYQ+ RG + +
Sbjct: 253 ALIALRYQLQRGVVVL 268
>BC040210-1|AAH40210.1| 323|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 323
Score = 206 bits (504), Expect = 1e-52
Identities = 98/196 (50%), Positives = 132/196 (67%), Gaps = 3/196 (1%)
Frame = +2
Query: 146 SCKREDLFITSKLWNTFHRPDLXRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTD 325
S KRED+F TSKLW HRP+L R ALE SL+NL +DY+DLYLIH+P + K + + P D
Sbjct: 73 SVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKD 132
Query: 326 ADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASV--KPVTNQVE 499
+GKI F VD TW+A+E GL +S+GVSNFN +QL+ IL+ + KPV NQVE
Sbjct: 133 ENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVE 192
Query: 500 CHPXLNQKRLKQFCEDRDIMITAYSPLGS-PDRPWAKPGDPQLMEDPKLKEIADRLGKTV 676
CHP NQ++L FC+ +DI++ AYS LGS + PW P P L+EDP L +A + +T
Sbjct: 193 CHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTP 252
Query: 677 AQVLIRYQIDRGNIXI 724
A + +RYQ+ RG + +
Sbjct: 253 ALIALRYQLQRGVVVL 268
>BC020216-1|AAH20216.1| 323|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 323
Score = 206 bits (504), Expect = 1e-52
Identities = 98/196 (50%), Positives = 132/196 (67%), Gaps = 3/196 (1%)
Frame = +2
Query: 146 SCKREDLFITSKLWNTFHRPDLXRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTD 325
S KRED+F TSKLW HRP+L R ALE SL+NL +DY+DLYLIH+P + K + + P D
Sbjct: 73 SVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKD 132
Query: 326 ADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASV--KPVTNQVE 499
+GKI F VD TW+A+E GL +S+GVSNFN +QL+ IL+ + KPV NQVE
Sbjct: 133 ENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVE 192
Query: 500 CHPXLNQKRLKQFCEDRDIMITAYSPLGS-PDRPWAKPGDPQLMEDPKLKEIADRLGKTV 676
CHP NQ++L FC+ +DI++ AYS LGS + PW P P L+EDP L +A + +T
Sbjct: 193 CHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTP 252
Query: 677 AQVLIRYQIDRGNIXI 724
A + +RYQ+ RG + +
Sbjct: 253 ALIALRYQLQRGVVVL 268
>BC015490-1|AAH15490.1| 323|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 323
Score = 206 bits (504), Expect = 1e-52
Identities = 98/196 (50%), Positives = 132/196 (67%), Gaps = 3/196 (1%)
Frame = +2
Query: 146 SCKREDLFITSKLWNTFHRPDLXRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTD 325
S KRED+F TSKLW HRP+L R ALE SL+NL +DY+DLYLIH+P + K + + P D
Sbjct: 73 SVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKD 132
Query: 326 ADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASV--KPVTNQVE 499
+GKI F VD TW+A+E GL +S+GVSNFN +QL+ IL+ + KPV NQVE
Sbjct: 133 ENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVE 192
Query: 500 CHPXLNQKRLKQFCEDRDIMITAYSPLGS-PDRPWAKPGDPQLMEDPKLKEIADRLGKTV 676
CHP NQ++L FC+ +DI++ AYS LGS + PW P P L+EDP L +A + +T
Sbjct: 193 CHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTP 252
Query: 677 AQVLIRYQIDRGNIXI 724
A + +RYQ+ RG + +
Sbjct: 253 ALIALRYQLQRGVVVL 268
>AL713867-3|CAI16410.1| 247|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 247
Score = 206 bits (504), Expect = 1e-52
Identities = 98/196 (50%), Positives = 132/196 (67%), Gaps = 3/196 (1%)
Frame = +2
Query: 146 SCKREDLFITSKLWNTFHRPDLXRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTD 325
S KRED+F TSKLW HRP+L R ALE SL+NL +DY+DLYLIH+P + K + + P D
Sbjct: 39 SVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKD 98
Query: 326 ADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASV--KPVTNQVE 499
+GKI F VD TW+A+E GL +S+GVSNFN +QL+ IL+ + KPV NQVE
Sbjct: 99 ENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVE 158
Query: 500 CHPXLNQKRLKQFCEDRDIMITAYSPLGS-PDRPWAKPGDPQLMEDPKLKEIADRLGKTV 676
CHP NQ++L FC+ +DI++ AYS LGS + PW P P L+EDP L +A + +T
Sbjct: 159 CHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTP 218
Query: 677 AQVLIRYQIDRGNIXI 724
A + +RYQ+ RG + +
Sbjct: 219 ALIALRYQLQRGVVVL 234
>AL713867-2|CAI16409.1| 323|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 323
Score = 206 bits (504), Expect = 1e-52
Identities = 98/196 (50%), Positives = 132/196 (67%), Gaps = 3/196 (1%)
Frame = +2
Query: 146 SCKREDLFITSKLWNTFHRPDLXRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTD 325
S KRED+F TSKLW HRP+L R ALE SL+NL +DY+DLYLIH+P + K + + P D
Sbjct: 73 SVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKD 132
Query: 326 ADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASV--KPVTNQVE 499
+GKI F VD TW+A+E GL +S+GVSNFN +QL+ IL+ + KPV NQVE
Sbjct: 133 ENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVE 192
Query: 500 CHPXLNQKRLKQFCEDRDIMITAYSPLGS-PDRPWAKPGDPQLMEDPKLKEIADRLGKTV 676
CHP NQ++L FC+ +DI++ AYS LGS + PW P P L+EDP L +A + +T
Sbjct: 193 CHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTP 252
Query: 677 AQVLIRYQIDRGNIXI 724
A + +RYQ+ RG + +
Sbjct: 253 ALIALRYQLQRGVVVL 268
>AB032150-1|BAA92886.1| 323|Homo sapiens 20 alph-hydroxysteroid
dehydrogenase protein.
Length = 323
Score = 206 bits (504), Expect = 1e-52
Identities = 98/196 (50%), Positives = 132/196 (67%), Gaps = 3/196 (1%)
Frame = +2
Query: 146 SCKREDLFITSKLWNTFHRPDLXRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTD 325
S KRED+F TSKLW HRP+L R ALE SL+NL +DY+DLYLIH+P + K + + P D
Sbjct: 73 SVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKD 132
Query: 326 ADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASV--KPVTNQVE 499
+GKI F VD TW+A+E GL +S+GVSNFN +QL+ IL+ + KPV NQVE
Sbjct: 133 ENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVE 192
Query: 500 CHPXLNQKRLKQFCEDRDIMITAYSPLGS-PDRPWAKPGDPQLMEDPKLKEIADRLGKTV 676
CHP NQ++L FC+ +DI++ AYS LGS + PW P P L+EDP L +A + +T
Sbjct: 193 CHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTP 252
Query: 677 AQVLIRYQIDRGNIXI 724
A + +RYQ+ RG + +
Sbjct: 253 ALIALRYQLQRGVVVL 268
>AB031083-1|BAA92883.1| 323|Homo sapiens 20 alpha-hydroxysteroid
dehydrogenase protein.
Length = 323
Score = 206 bits (504), Expect = 1e-52
Identities = 98/196 (50%), Positives = 132/196 (67%), Gaps = 3/196 (1%)
Frame = +2
Query: 146 SCKREDLFITSKLWNTFHRPDLXRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTD 325
S KRED+F TSKLW HRP+L R ALE SL+NL +DY+DLYLIH+P + K + + P D
Sbjct: 73 SVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKD 132
Query: 326 ADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASV--KPVTNQVE 499
+GKI F VD TW+A+E GL +S+GVSNFN +QL+ IL+ + KPV NQVE
Sbjct: 133 ENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVE 192
Query: 500 CHPXLNQKRLKQFCEDRDIMITAYSPLGS-PDRPWAKPGDPQLMEDPKLKEIADRLGKTV 676
CHP NQ++L FC+ +DI++ AYS LGS + PW P P L+EDP L +A + +T
Sbjct: 193 CHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTP 252
Query: 677 AQVLIRYQIDRGNIXI 724
A + +RYQ+ RG + +
Sbjct: 253 ALIALRYQLQRGVVVL 268
>U05598-1|AAA20937.1| 323|Homo sapiens dihydrodiol dehydrogenase
protein.
Length = 323
Score = 206 bits (502), Expect = 2e-52
Identities = 97/196 (49%), Positives = 132/196 (67%), Gaps = 3/196 (1%)
Frame = +2
Query: 146 SCKREDLFITSKLWNTFHRPDLXRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTD 325
S KRED+F TSKLW+ HRP+L R ALE SL+NL +DY+DLYLIH+P + K + + P D
Sbjct: 73 SVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKD 132
Query: 326 ADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASV--KPVTNQVE 499
+GKI F VD TW+A+E GL +S+GVSNFN + L+ IL+ + KPV NQVE
Sbjct: 133 ENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKYKPVCNQVE 192
Query: 500 CHPXLNQKRLKQFCEDRDIMITAYSPLGS-PDRPWAKPGDPQLMEDPKLKEIADRLGKTV 676
CHP NQ++L FC+ +DI++ AYS LGS + PW P P L+EDP L +A + +T
Sbjct: 193 CHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTP 252
Query: 677 AQVLIRYQIDRGNIXI 724
A + +RYQ+ RG + +
Sbjct: 253 ALIALRYQLQRGVVVL 268
>S68330-1|AAD14013.1| 323|Homo sapiens chlordecone reductase
homolog protein.
Length = 323
Score = 206 bits (502), Expect = 2e-52
Identities = 97/196 (49%), Positives = 132/196 (67%), Gaps = 3/196 (1%)
Frame = +2
Query: 146 SCKREDLFITSKLWNTFHRPDLXRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTD 325
S KRED+F TSKLW+ HRP+L R ALE SL+NL +DY+DLYLIH+P + K + + P D
Sbjct: 73 SVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKD 132
Query: 326 ADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVK--PVTNQVE 499
+GKI F VD TW+A+E GL +S+GVSNFN + L+ IL+ +K PV NQVE
Sbjct: 133 ENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNEPGLKYEPVCNQVE 192
Query: 500 CHPXLNQKRLKQFCEDRDIMITAYSPLGS-PDRPWAKPGDPQLMEDPKLKEIADRLGKTV 676
CHP NQ++L FC+ +DI++ AYS LGS + PW P P L+EDP L +A + +T
Sbjct: 193 CHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTP 252
Query: 677 AQVLIRYQIDRGNIXI 724
A + +RYQ+ RG + +
Sbjct: 253 ALIALRYQLQRGVVVL 268
>BT006653-1|AAP35299.1| 323|Homo sapiens aldo-keto reductase family
1, member C2 (dihydrodiol dehydrogenase 2; bile acid
protein.
Length = 323
Score = 206 bits (502), Expect = 2e-52
Identities = 97/196 (49%), Positives = 132/196 (67%), Gaps = 3/196 (1%)
Frame = +2
Query: 146 SCKREDLFITSKLWNTFHRPDLXRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTD 325
S KRED+F TSKLW+ HRP+L R ALE SL+NL +DY+DLYLIH+P + K + + P D
Sbjct: 73 SVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKD 132
Query: 326 ADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASV--KPVTNQVE 499
+GKI F VD TW+A+E GL +S+GVSNFN + L+ IL+ + KPV NQVE
Sbjct: 133 ENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKYKPVCNQVE 192
Query: 500 CHPXLNQKRLKQFCEDRDIMITAYSPLGS-PDRPWAKPGDPQLMEDPKLKEIADRLGKTV 676
CHP NQ++L FC+ +DI++ AYS LGS + PW P P L+EDP L +A + +T
Sbjct: 193 CHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTP 252
Query: 677 AQVLIRYQIDRGNIXI 724
A + +RYQ+ RG + +
Sbjct: 253 ALIALRYQLQRGVVVL 268
>BC063574-1|AAH63574.1| 323|Homo sapiens aldo-keto reductase family
1, member C2 (dihydrodiol dehydrogenase 2; bile acid
protein.
Length = 323
Score = 206 bits (502), Expect = 2e-52
Identities = 97/196 (49%), Positives = 132/196 (67%), Gaps = 3/196 (1%)
Frame = +2
Query: 146 SCKREDLFITSKLWNTFHRPDLXRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTD 325
S KRED+F TSKLW+ HRP+L R ALE SL+NL +DY+DLYLIH+P + K + + P D
Sbjct: 73 SVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKD 132
Query: 326 ADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASV--KPVTNQVE 499
+GKI F VD TW+A+E GL +S+GVSNFN + L+ IL+ + KPV NQVE
Sbjct: 133 ENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKYKPVCNQVE 192
Query: 500 CHPXLNQKRLKQFCEDRDIMITAYSPLGS-PDRPWAKPGDPQLMEDPKLKEIADRLGKTV 676
CHP NQ++L FC+ +DI++ AYS LGS + PW P P L+EDP L +A + +T
Sbjct: 193 CHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTP 252
Query: 677 AQVLIRYQIDRGNIXI 724
A + +RYQ+ RG + +
Sbjct: 253 ALIALRYQLQRGVVVL 268
>BC007024-1|AAH07024.1| 323|Homo sapiens aldo-keto reductase family
1, member C2 (dihydrodiol dehydrogenase 2; bile acid
protein.
Length = 323
Score = 206 bits (502), Expect = 2e-52
Identities = 97/196 (49%), Positives = 132/196 (67%), Gaps = 3/196 (1%)
Frame = +2
Query: 146 SCKREDLFITSKLWNTFHRPDLXRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTD 325
S KRED+F TSKLW+ HRP+L R ALE SL+NL +DY+DLYLIH+P + K + + P D
Sbjct: 73 SVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKD 132
Query: 326 ADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASV--KPVTNQVE 499
+GKI F VD TW+A+E GL +S+GVSNFN + L+ IL+ + KPV NQVE
Sbjct: 133 ENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKYKPVCNQVE 192
Query: 500 CHPXLNQKRLKQFCEDRDIMITAYSPLGS-PDRPWAKPGDPQLMEDPKLKEIADRLGKTV 676
CHP NQ++L FC+ +DI++ AYS LGS + PW P P L+EDP L +A + +T
Sbjct: 193 CHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTP 252
Query: 677 AQVLIRYQIDRGNIXI 724
A + +RYQ+ RG + +
Sbjct: 253 ALIALRYQLQRGVVVL 268
>AL713867-1|CAI16408.1| 323|Homo sapiens aldo-keto reductase family
1, member C2 (dihydrodiol dehydrogenase 2; bile acid
protein.
Length = 323
Score = 206 bits (502), Expect = 2e-52
Identities = 97/196 (49%), Positives = 132/196 (67%), Gaps = 3/196 (1%)
Frame = +2
Query: 146 SCKREDLFITSKLWNTFHRPDLXRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTD 325
S KRED+F TSKLW+ HRP+L R ALE SL+NL +DY+DLYLIH+P + K + + P D
Sbjct: 73 SVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKD 132
Query: 326 ADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASV--KPVTNQVE 499
+GKI F VD TW+A+E GL +S+GVSNFN + L+ IL+ + KPV NQVE
Sbjct: 133 ENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKYKPVCNQVE 192
Query: 500 CHPXLNQKRLKQFCEDRDIMITAYSPLGS-PDRPWAKPGDPQLMEDPKLKEIADRLGKTV 676
CHP NQ++L FC+ +DI++ AYS LGS + PW P P L+EDP L +A + +T
Sbjct: 193 CHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTP 252
Query: 677 AQVLIRYQIDRGNIXI 724
A + +RYQ+ RG + +
Sbjct: 253 ALIALRYQLQRGVVVL 268
>AL391427-1|CAI14726.1| 323|Homo sapiens aldo-keto reductase family
1, member C2 (dihydrodiol dehydrogenase 2; bile acid
protein.
Length = 323
Score = 206 bits (502), Expect = 2e-52
Identities = 97/196 (49%), Positives = 132/196 (67%), Gaps = 3/196 (1%)
Frame = +2
Query: 146 SCKREDLFITSKLWNTFHRPDLXRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTD 325
S KRED+F TSKLW+ HRP+L R ALE SL+NL +DY+DLYLIH+P + K + + P D
Sbjct: 73 SVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKD 132
Query: 326 ADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASV--KPVTNQVE 499
+GKI F VD TW+A+E GL +S+GVSNFN + L+ IL+ + KPV NQVE
Sbjct: 133 ENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKYKPVCNQVE 192
Query: 500 CHPXLNQKRLKQFCEDRDIMITAYSPLGS-PDRPWAKPGDPQLMEDPKLKEIADRLGKTV 676
CHP NQ++L FC+ +DI++ AYS LGS + PW P P L+EDP L +A + +T
Sbjct: 193 CHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTP 252
Query: 677 AQVLIRYQIDRGNIXI 724
A + +RYQ+ RG + +
Sbjct: 253 ALIALRYQLQRGVVVL 268
>AB032153-1|BAA92891.1| 323|Homo sapiens bile acid-binding protein
protein.
Length = 323
Score = 206 bits (502), Expect = 2e-52
Identities = 97/196 (49%), Positives = 132/196 (67%), Gaps = 3/196 (1%)
Frame = +2
Query: 146 SCKREDLFITSKLWNTFHRPDLXRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTD 325
S KRED+F TSKLW+ HRP+L R ALE SL+NL +DY+DLYLIH+P + K + + P D
Sbjct: 73 SVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKD 132
Query: 326 ADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASV--KPVTNQVE 499
+GKI F VD TW+A+E GL +S+GVSNFN + L+ IL+ + KPV NQVE
Sbjct: 133 ENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKYKPVCNQVE 192
Query: 500 CHPXLNQKRLKQFCEDRDIMITAYSPLGS-PDRPWAKPGDPQLMEDPKLKEIADRLGKTV 676
CHP NQ++L FC+ +DI++ AYS LGS + PW P P L+EDP L +A + +T
Sbjct: 193 CHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTP 252
Query: 677 AQVLIRYQIDRGNIXI 724
A + +RYQ+ RG + +
Sbjct: 253 ALIALRYQLQRGVVVL 268
>AB031084-1|BAA92884.1| 323|Homo sapiens bile acid-binding protein
protein.
Length = 323
Score = 206 bits (502), Expect = 2e-52
Identities = 97/196 (49%), Positives = 132/196 (67%), Gaps = 3/196 (1%)
Frame = +2
Query: 146 SCKREDLFITSKLWNTFHRPDLXRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTD 325
S KRED+F TSKLW+ HRP+L R ALE SL+NL +DY+DLYLIH+P + K + + P D
Sbjct: 73 SVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKD 132
Query: 326 ADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASV--KPVTNQVE 499
+GKI F VD TW+A+E GL +S+GVSNFN + L+ IL+ + KPV NQVE
Sbjct: 133 ENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKYKPVCNQVE 192
Query: 500 CHPXLNQKRLKQFCEDRDIMITAYSPLGS-PDRPWAKPGDPQLMEDPKLKEIADRLGKTV 676
CHP NQ++L FC+ +DI++ AYS LGS + PW P P L+EDP L +A + +T
Sbjct: 193 CHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTP 252
Query: 677 AQVLIRYQIDRGNIXI 724
A + +RYQ+ RG + +
Sbjct: 253 ALIALRYQLQRGVVVL 268
>AB021654-1|BAA36169.1| 323|Homo sapiens DD2/bile acid-binding
protein/AKR1C2/3alpha-hydroxysteroid dehydrogenase type
3 protein.
Length = 323
Score = 206 bits (502), Expect = 2e-52
Identities = 97/196 (49%), Positives = 132/196 (67%), Gaps = 3/196 (1%)
Frame = +2
Query: 146 SCKREDLFITSKLWNTFHRPDLXRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTD 325
S KRED+F TSKLW+ HRP+L R ALE SL+NL +DY+DLYLIH+P + K + + P D
Sbjct: 73 SVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKD 132
Query: 326 ADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASV--KPVTNQVE 499
+GKI F VD TW+A+E GL +S+GVSNFN + L+ IL+ + KPV NQVE
Sbjct: 133 ENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKYKPVCNQVE 192
Query: 500 CHPXLNQKRLKQFCEDRDIMITAYSPLGS-PDRPWAKPGDPQLMEDPKLKEIADRLGKTV 676
CHP NQ++L FC+ +DI++ AYS LGS + PW P P L+EDP L +A + +T
Sbjct: 193 CHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTP 252
Query: 677 AQVLIRYQIDRGNIXI 724
A + +RYQ+ RG + +
Sbjct: 253 ALIALRYQLQRGVVVL 268
>D17793-1|BAA04619.2| 325|Homo sapiens KIAA0119 protein.
Length = 325
Score = 205 bits (501), Expect = 3e-52
Identities = 97/196 (49%), Positives = 132/196 (67%), Gaps = 3/196 (1%)
Frame = +2
Query: 146 SCKREDLFITSKLWNTFHRPDLXRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTD 325
S KRED+F TSKLW+TFHRP+L R ALE SL+ +DY+DLYLIH P + K + + PTD
Sbjct: 75 SVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLKPGEELSPTD 134
Query: 326 ADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASV--KPVTNQVE 499
+GK+ F VD TW+A+E GL +S+GVSNFN +QL+ IL+ + KPV NQVE
Sbjct: 135 ENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVE 194
Query: 500 CHPXLNQKRLKQFCEDRDIMITAYSPLGSP-DRPWAKPGDPQLMEDPKLKEIADRLGKTV 676
CHP N+ +L FC+ +DI++ AYS LGS D+ W P P L+EDP L +A + +T
Sbjct: 195 CHPYFNRSKLLDFCKSKDIVLVAYSALGSQRDKRWVDPNSPVLLEDPVLCALAKKHKRTP 254
Query: 677 AQVLIRYQIDRGNIXI 724
A + +RYQ+ RG + +
Sbjct: 255 ALIALRYQLQRGVVVL 270
>BT007286-1|AAP35950.1| 323|Homo sapiens aldo-keto reductase family
1, member C3 (3-alpha hydroxysteroid dehydrogenase,
protein.
Length = 323
Score = 205 bits (501), Expect = 3e-52
Identities = 97/196 (49%), Positives = 132/196 (67%), Gaps = 3/196 (1%)
Frame = +2
Query: 146 SCKREDLFITSKLWNTFHRPDLXRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTD 325
S KRED+F TSKLW+TFHRP+L R ALE SL+ +DY+DLYLIH P + K + + PTD
Sbjct: 73 SVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLKPGEELSPTD 132
Query: 326 ADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASV--KPVTNQVE 499
+GK+ F VD TW+A+E GL +S+GVSNFN +QL+ IL+ + KPV NQVE
Sbjct: 133 ENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVE 192
Query: 500 CHPXLNQKRLKQFCEDRDIMITAYSPLGSP-DRPWAKPGDPQLMEDPKLKEIADRLGKTV 676
CHP N+ +L FC+ +DI++ AYS LGS D+ W P P L+EDP L +A + +T
Sbjct: 193 CHPYFNRSKLLDFCKSKDIVLVAYSALGSQRDKRWVDPNSPVLLEDPVLCALAKKHKRTP 252
Query: 677 AQVLIRYQIDRGNIXI 724
A + +RYQ+ RG + +
Sbjct: 253 ALIALRYQLQRGVVVL 268
>BC019230-1|AAH19230.1| 323|Homo sapiens aldo-keto reductase family
1, member C3 (3-alpha hydroxysteroid dehydrogenase,
protein.
Length = 323
Score = 205 bits (501), Expect = 3e-52
Identities = 97/196 (49%), Positives = 132/196 (67%), Gaps = 3/196 (1%)
Frame = +2
Query: 146 SCKREDLFITSKLWNTFHRPDLXRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTD 325
S KRED+F TSKLW+TFHRP+L R ALE SL+ +DY+DLYLIH P + K + + PTD
Sbjct: 73 SVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLKPGEELSPTD 132
Query: 326 ADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASV--KPVTNQVE 499
+GK+ F VD TW+A+E GL +S+GVSNFN +QL+ IL+ + KPV NQVE
Sbjct: 133 ENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVE 192
Query: 500 CHPXLNQKRLKQFCEDRDIMITAYSPLGSP-DRPWAKPGDPQLMEDPKLKEIADRLGKTV 676
CHP N+ +L FC+ +DI++ AYS LGS D+ W P P L+EDP L +A + +T
Sbjct: 193 CHPYFNRSKLLDFCKSKDIVLVAYSALGSQRDKRWVDPNSPVLLEDPVLCALAKKHKRTP 252
Query: 677 AQVLIRYQIDRGNIXI 724
A + +RYQ+ RG + +
Sbjct: 253 ALIALRYQLQRGVVVL 268
>BC001479-1|AAH01479.1| 323|Homo sapiens aldo-keto reductase family
1, member C3 (3-alpha hydroxysteroid dehydrogenase,
protein.
Length = 323
Score = 205 bits (501), Expect = 3e-52
Identities = 97/196 (49%), Positives = 132/196 (67%), Gaps = 3/196 (1%)
Frame = +2
Query: 146 SCKREDLFITSKLWNTFHRPDLXRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTD 325
S KRED+F TSKLW+TFHRP+L R ALE SL+ +DY+DLYLIH P + K + + PTD
Sbjct: 73 SVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLKPGEELSPTD 132
Query: 326 ADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASV--KPVTNQVE 499
+GK+ F VD TW+A+E GL +S+GVSNFN +QL+ IL+ + KPV NQVE
Sbjct: 133 ENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVE 192
Query: 500 CHPXLNQKRLKQFCEDRDIMITAYSPLGSP-DRPWAKPGDPQLMEDPKLKEIADRLGKTV 676
CHP N+ +L FC+ +DI++ AYS LGS D+ W P P L+EDP L +A + +T
Sbjct: 193 CHPYFNRSKLLDFCKSKDIVLVAYSALGSQRDKRWVDPNSPVLLEDPVLCALAKKHKRTP 252
Query: 677 AQVLIRYQIDRGNIXI 724
A + +RYQ+ RG + +
Sbjct: 253 ALIALRYQLQRGVVVL 268
>AL391427-4|CAI14729.1| 323|Homo sapiens aldo-keto reductase family
1, member C3 (3-alpha hydroxysteroid dehydrogenase,
protein.
Length = 323
Score = 205 bits (501), Expect = 3e-52
Identities = 97/196 (49%), Positives = 132/196 (67%), Gaps = 3/196 (1%)
Frame = +2
Query: 146 SCKREDLFITSKLWNTFHRPDLXRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTD 325
S KRED+F TSKLW+TFHRP+L R ALE SL+ +DY+DLYLIH P + K + + PTD
Sbjct: 73 SVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLKPGEELSPTD 132
Query: 326 ADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASV--KPVTNQVE 499
+GK+ F VD TW+A+E GL +S+GVSNFN +QL+ IL+ + KPV NQVE
Sbjct: 133 ENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVE 192
Query: 500 CHPXLNQKRLKQFCEDRDIMITAYSPLGSP-DRPWAKPGDPQLMEDPKLKEIADRLGKTV 676
CHP N+ +L FC+ +DI++ AYS LGS D+ W P P L+EDP L +A + +T
Sbjct: 193 CHPYFNRSKLLDFCKSKDIVLVAYSALGSQRDKRWVDPNSPVLLEDPVLCALAKKHKRTP 252
Query: 677 AQVLIRYQIDRGNIXI 724
A + +RYQ+ RG + +
Sbjct: 253 ALIALRYQLQRGVVVL 268
>AB032157-1|BAA92892.1| 323|Homo sapiens prostaglandin F synthase
protein.
Length = 323
Score = 205 bits (501), Expect = 3e-52
Identities = 97/196 (49%), Positives = 132/196 (67%), Gaps = 3/196 (1%)
Frame = +2
Query: 146 SCKREDLFITSKLWNTFHRPDLXRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTD 325
S KRED+F TSKLW+TFHRP+L R ALE SL+ +DY+DLYLIH P + K + + PTD
Sbjct: 73 SVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLKPGEELSPTD 132
Query: 326 ADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASV--KPVTNQVE 499
+GK+ F VD TW+A+E GL +S+GVSNFN +QL+ IL+ + KPV NQVE
Sbjct: 133 ENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVE 192
Query: 500 CHPXLNQKRLKQFCEDRDIMITAYSPLGSP-DRPWAKPGDPQLMEDPKLKEIADRLGKTV 676
CHP N+ +L FC+ +DI++ AYS LGS D+ W P P L+EDP L +A + +T
Sbjct: 193 CHPYFNRSKLLDFCKSKDIVLVAYSALGSQRDKRWVDPNSPVLLEDPVLCALAKKHKRTP 252
Query: 677 AQVLIRYQIDRGNIXI 724
A + +RYQ+ RG + +
Sbjct: 253 ALIALRYQLQRGVVVL 268
>AB018580-1|BAA88488.1| 323|Homo sapiens hluPGFS protein.
Length = 323
Score = 205 bits (501), Expect = 3e-52
Identities = 97/196 (49%), Positives = 132/196 (67%), Gaps = 3/196 (1%)
Frame = +2
Query: 146 SCKREDLFITSKLWNTFHRPDLXRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTD 325
S KRED+F TSKLW+TFHRP+L R ALE SL+ +DY+DLYLIH P + K + + PTD
Sbjct: 73 SVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLKPGEELSPTD 132
Query: 326 ADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASV--KPVTNQVE 499
+GK+ F VD TW+A+E GL +S+GVSNFN +QL+ IL+ + KPV NQVE
Sbjct: 133 ENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVE 192
Query: 500 CHPXLNQKRLKQFCEDRDIMITAYSPLGSP-DRPWAKPGDPQLMEDPKLKEIADRLGKTV 676
CHP N+ +L FC+ +DI++ AYS LGS D+ W P P L+EDP L +A + +T
Sbjct: 193 CHPYFNRSKLLDFCKSKDIVLVAYSALGSQRDKRWVDPNSPVLLEDPVLCALAKKHKRTP 252
Query: 677 AQVLIRYQIDRGNIXI 724
A + +RYQ+ RG + +
Sbjct: 253 ALIALRYQLQRGVVVL 268
>L32592-1|AAB38486.1| 323|Homo sapiens dihydrodiol
dehydrogenase/bile acid-binding protein protein.
Length = 323
Score = 205 bits (500), Expect = 4e-52
Identities = 97/196 (49%), Positives = 131/196 (66%), Gaps = 3/196 (1%)
Frame = +2
Query: 146 SCKREDLFITSKLWNTFHRPDLXRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTD 325
S KRED+F TSKLW+ HRP+L R ALE SL+NL +DY DLYLIH+P + K + + P D
Sbjct: 73 SVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYADLYLIHFPVSVKPGEEVIPKD 132
Query: 326 ADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVK--PVTNQVE 499
+GKI F VD TW+A+E GL +S+GVSNFN + L+ IL+ +K PV NQVE
Sbjct: 133 ENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNEPGLKYEPVCNQVE 192
Query: 500 CHPXLNQKRLKQFCEDRDIMITAYSPLGS-PDRPWAKPGDPQLMEDPKLKEIADRLGKTV 676
CHP NQ++L FC+ +DI++ AYS LGS + PW P P L+EDP L +A + +T
Sbjct: 193 CHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTP 252
Query: 677 AQVLIRYQIDRGNIXI 724
A + +RYQ+ RG + +
Sbjct: 253 ALIALRYQLQRGVVVL 268
>S68288-1|AAD14011.1| 323|Homo sapiens chlordecone reductase
homolog protein.
Length = 323
Score = 203 bits (495), Expect = 2e-51
Identities = 96/196 (48%), Positives = 132/196 (67%), Gaps = 3/196 (1%)
Frame = +2
Query: 146 SCKREDLFITSKLWNTFHRPDLXRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTD 325
S +RED+F TSKLW+TFHRP+L R ALE SL+ +DY+DLYLIH P + K + + PTD
Sbjct: 73 SVEREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLKPGEELSPTD 132
Query: 326 ADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASV--KPVTNQVE 499
+GK+ F VD TW+A+E GL +S+GVSNFN +QL+ IL+ + KPV NQVE
Sbjct: 133 ENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEIILNKPGLKYKPVCNQVE 192
Query: 500 CHPXLNQKRLKQFCEDRDIMITAYSPLGSP-DRPWAKPGDPQLMEDPKLKEIADRLGKTV 676
CHP N+ +L FC+ +DI++ AYS LGS D+ W P P L+EDP L +A + +T
Sbjct: 193 CHPYFNRSKLLDFCKSKDIVLVAYSALGSQRDKRWVDPNSPVLLEDPVLCALAKKHKRTP 252
Query: 677 AQVLIRYQIDRGNIXI 724
A + +RYQ+ RG + +
Sbjct: 253 ALIALRYQLQRGVVVL 268
>L43839-1|AAB41916.1| 323|Homo sapiens 3-alpha-hydroxysteroid
dehydrogenase protein.
Length = 323
Score = 202 bits (493), Expect = 3e-51
Identities = 96/196 (48%), Positives = 131/196 (66%), Gaps = 3/196 (1%)
Frame = +2
Query: 146 SCKREDLFITSKLWNTFHRPDLXRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTD 325
S RED+F TSKLW+TFHRP+L R ALE SL+ +DY+DLYLIH P + K + + PTD
Sbjct: 73 SVMREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLKPGEELSPTD 132
Query: 326 ADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASV--KPVTNQVE 499
+GK+ F VD TW+A+E GL +S+GVSNFN +QL+ IL+ + KPV NQVE
Sbjct: 133 ENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEIILNKPGLKYKPVCNQVE 192
Query: 500 CHPXLNQKRLKQFCEDRDIMITAYSPLGSP-DRPWAKPGDPQLMEDPKLKEIADRLGKTV 676
CHP N+ +L FC+ +DI++ AYS LGS D+ W P P L+EDP L +A + +T
Sbjct: 193 CHPYFNRSKLLDFCKSKDIVLVAYSALGSQRDKRWVDPNSPVLLEDPVLCALAKKHKRTP 252
Query: 677 AQVLIRYQIDRGNIXI 724
A + +RYQ+ RG + +
Sbjct: 253 ALIALRYQLQRGVVVL 268
>AF149416-1|AAF07272.2| 323|Homo sapiens 3-alpha hydroxysteroid
dehydrogenase type IIb protein.
Length = 323
Score = 202 bits (493), Expect = 3e-51
Identities = 96/196 (48%), Positives = 131/196 (66%), Gaps = 3/196 (1%)
Frame = +2
Query: 146 SCKREDLFITSKLWNTFHRPDLXRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTD 325
S KRED+F TSKLW+T HRP+L R ALE SL+ +DY+DLYLIH P + K + + PTD
Sbjct: 73 SVKREDIFYTSKLWSTSHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLKPGEELSPTD 132
Query: 326 ADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASV--KPVTNQVE 499
+GK+ F VD TW+A+E GL +S+GVSNFN +QL+ IL+ + KPV NQVE
Sbjct: 133 ENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVE 192
Query: 500 CHPXLNQKRLKQFCEDRDIMITAYSPLGSP-DRPWAKPGDPQLMEDPKLKEIADRLGKTV 676
CHP N+ +L FC+ +DI++ AYS LGS D+ W P P L+EDP L +A + +T
Sbjct: 193 CHPYFNRSKLLDFCKSKDIVLVAYSALGSQRDKRWVDPNSPVLLEDPVLCALAKKHKRTP 252
Query: 677 AQVLIRYQIDRGNIXI 724
A + +RYQ+ RG + +
Sbjct: 253 ALIALRYQLQRGVVVL 268
>S68290-1|AAD14012.1| 320|Homo sapiens chlordecone reductase
homolog protein.
Length = 320
Score = 201 bits (491), Expect = 5e-51
Identities = 97/196 (49%), Positives = 129/196 (65%), Gaps = 3/196 (1%)
Frame = +2
Query: 146 SCKREDLFITSKLWNTFHRPDLXRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTD 325
S KRED+F TSKLW HRP+L R ALE SL+NL +DY+DLYLIH+P + K + + P D
Sbjct: 70 SVKREDIFYTSKLWCNSHRPELDRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKD 129
Query: 326 ADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILD--NASVKPVTNQVE 499
+GKI F VD TW+A+E L +S+GVSNFN L+ IL+ VKPV NQVE
Sbjct: 130 ENGKILFDTVDLCATWEAVEKCKDAELAKSIGVSNFNRSTLEMILNKPGLQVKPVCNQVE 189
Query: 500 CHPXLNQKRLKQFCEDRDIMITAYSPLGS-PDRPWAKPGDPQLMEDPKLKEIADRLGKTV 676
CHP NQ++L FC+ +DI++ AYS LGS + PW P P L+EDP L +A + +T
Sbjct: 190 CHPYFNQRKLLDFCKSKDIVLVAYSALGSLREEPWVDPNSPVLLEDPVLCALAKKHKRTP 249
Query: 677 AQVLIRYQIDRGNIXI 724
A + +RYQ+ RG + +
Sbjct: 250 ALIALRYQLQRGVVVL 265
>DQ269985-1|ABB76132.1| 323|Homo sapiens type II 3a-hydroxysteroid
dehydrogenase variant protein.
Length = 323
Score = 198 bits (484), Expect = 3e-50
Identities = 95/196 (48%), Positives = 129/196 (65%), Gaps = 3/196 (1%)
Frame = +2
Query: 146 SCKREDLFITSKLWNTFHRPDLXRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTD 325
S KRED+F TSKLW HRP+L R ALE SL+ +DY+DLYLIH P + K + + PTD
Sbjct: 73 SVKREDIFYTSKLWCNSHRPELVRPALERSLKKAQLDYVDLYLIHSPMSLKPGEELSPTD 132
Query: 326 ADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASV--KPVTNQVE 499
+GK+ F VD TW+A+E GL +S+GVSNFN +QL+ IL+ + KPV NQVE
Sbjct: 133 ENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVE 192
Query: 500 CHPXLNQKRLKQFCEDRDIMITAYSPLGSP-DRPWAKPGDPQLMEDPKLKEIADRLGKTV 676
CHP N+ +L FC+ +DI++ AYS LGS D+ W P P L+EDP L +A + +T
Sbjct: 193 CHPYFNRSKLLDFCKSKDIVLVAYSALGSQRDKRWVDPNSPVLLEDPVLCALAKKHKRTP 252
Query: 677 AQVLIRYQIDRGNIXI 724
A + +RYQ+ RG + +
Sbjct: 253 ALIALRYQLQRGVVVL 268
>AB045829-1|BAA99542.1| 323|Homo sapiens 3alpha-hydroxysteroid
dehydrogenase variant protein.
Length = 323
Score = 192 bits (468), Expect = 3e-48
Identities = 91/196 (46%), Positives = 128/196 (65%), Gaps = 3/196 (1%)
Frame = +2
Query: 146 SCKREDLFITSKLWNTFHRPDLXRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTD 325
S KRED+F TSKLW TF +P + + ALE SL+ L +DY+DLYL+H+P A K + P D
Sbjct: 73 SVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALKPGETPLPKD 132
Query: 326 ADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASV--KPVTNQVE 499
+GK+ F VD TW+ +E GL +S+GVSNFN +QL+ IL+ + KPV NQVE
Sbjct: 133 ENGKVIFDTVDLCATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILNKPGLKYKPVCNQVE 192
Query: 500 CHPXLNQKRLKQFCEDRDIMITAYSPLGSP-DRPWAKPGDPQLMEDPKLKEIADRLGKTV 676
CHP LNQ +L FC+ +DI++ A+S LG+ + W P P L+EDP L +A + +T
Sbjct: 193 CHPYLNQSKLLDFCKSKDIVLVAHSALGTQRHKLWVDPNSPVLLEDPVLCALAKKHKRTP 252
Query: 677 AQVLIRYQIDRGNIXI 724
A + +RYQ+ RG + +
Sbjct: 253 ALIALRYQLQRGVVVL 268
>S68287-1|AAD14010.1| 323|Homo sapiens chlordecone reductase
protein.
Length = 323
Score = 192 bits (467), Expect = 4e-48
Identities = 91/196 (46%), Positives = 128/196 (65%), Gaps = 3/196 (1%)
Frame = +2
Query: 146 SCKREDLFITSKLWNTFHRPDLXRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTD 325
S KRED+F TSKLW TF +P + + ALE SL+ L +DY+DLYL+H+P A K + P D
Sbjct: 73 SVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALKPGETPLPKD 132
Query: 326 ADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASV--KPVTNQVE 499
+GK+ F VD TW+ +E GL +S+GVSNFN +QL+ IL+ + KPV NQVE
Sbjct: 133 ENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILNKPGLKYKPVCNQVE 192
Query: 500 CHPXLNQKRLKQFCEDRDIMITAYSPLGSP-DRPWAKPGDPQLMEDPKLKEIADRLGKTV 676
CHP LNQ +L FC+ +DI++ A+S LG+ + W P P L+EDP L +A + +T
Sbjct: 193 CHPYLNQSKLLDFCKSKDIVLVAHSALGTQRHKLWVDPNSPVLLEDPVLCALAKKHKRTP 252
Query: 677 AQVLIRYQIDRGNIXI 724
A + +RYQ+ RG + +
Sbjct: 253 ALIALRYQLQRGVVVL 268
>M33375-1|AAA35658.1| 308|Homo sapiens protein ( Human chlordecone
reductase mRNA, complete cds. ).
Length = 308
Score = 192 bits (467), Expect = 4e-48
Identities = 91/196 (46%), Positives = 128/196 (65%), Gaps = 3/196 (1%)
Frame = +2
Query: 146 SCKREDLFITSKLWNTFHRPDLXRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTD 325
S KRED+F TSKLW TF +P + + ALE SL+ L +DY+DLYL+H+P A K + P D
Sbjct: 58 SVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALKPGETPLPKD 117
Query: 326 ADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASV--KPVTNQVE 499
+GK+ F VD TW+ +E GL +S+GVSNFN +QL+ IL+ + KPV NQVE
Sbjct: 118 ENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILNKPGLKYKPVCNQVE 177
Query: 500 CHPXLNQKRLKQFCEDRDIMITAYSPLGSP-DRPWAKPGDPQLMEDPKLKEIADRLGKTV 676
CHP LNQ +L FC+ +DI++ A+S LG+ + W P P L+EDP L +A + +T
Sbjct: 178 CHPYLNQSKLLDFCKSKDIVLVAHSALGTQRHKLWVDPNSPVLLEDPVLCALAKKHKRTP 237
Query: 677 AQVLIRYQIDRGNIXI 724
A + +RYQ+ RG + +
Sbjct: 238 ALIALRYQLQRGVVVL 253
>D26125-1|BAA05122.1| 321|Homo sapiens 3
alpha-hydroxysteroid/dihydrodiol dehydrogenase DD4
protein.
Length = 321
Score = 192 bits (467), Expect = 4e-48
Identities = 91/196 (46%), Positives = 128/196 (65%), Gaps = 3/196 (1%)
Frame = +2
Query: 146 SCKREDLFITSKLWNTFHRPDLXRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTD 325
S KRED+F TSKLW TF +P + + ALE SL+ L +DY+DLYL+H+P A K + P D
Sbjct: 71 SVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALKPGETPLPKD 130
Query: 326 ADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASV--KPVTNQVE 499
+GK+ F VD TW+ +E GL +S+GVSNFN +QL+ IL+ + KPV NQVE
Sbjct: 131 ENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILNKPGLKYKPVCNQVE 190
Query: 500 CHPXLNQKRLKQFCEDRDIMITAYSPLGSP-DRPWAKPGDPQLMEDPKLKEIADRLGKTV 676
CHP LNQ +L FC+ +DI++ A+S LG+ + W P P L+EDP L +A + +T
Sbjct: 191 CHPYLNQSKLLDFCKSKDIVLVAHSALGTQRHKLWVDPNSPVLLEDPVLCALAKKHKRTP 250
Query: 677 AQVLIRYQIDRGNIXI 724
A + +RYQ+ RG + +
Sbjct: 251 ALIALRYQLQRGVVVL 266
>AB032163-1|BAA92893.1| 323|Homo sapiens dihydrodiol dehydrogenase
4 protein.
Length = 323
Score = 192 bits (467), Expect = 4e-48
Identities = 91/196 (46%), Positives = 128/196 (65%), Gaps = 3/196 (1%)
Frame = +2
Query: 146 SCKREDLFITSKLWNTFHRPDLXRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTD 325
S KRED+F TSKLW TF +P + + ALE SL+ L +DY+DLYL+H+P A K + P D
Sbjct: 73 SVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALKPGETPLPKD 132
Query: 326 ADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASV--KPVTNQVE 499
+GK+ F VD TW+ +E GL +S+GVSNFN +QL+ IL+ + KPV NQVE
Sbjct: 133 ENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILNKPGLKYKPVCNQVE 192
Query: 500 CHPXLNQKRLKQFCEDRDIMITAYSPLGSP-DRPWAKPGDPQLMEDPKLKEIADRLGKTV 676
CHP LNQ +L FC+ +DI++ A+S LG+ + W P P L+EDP L +A + +T
Sbjct: 193 CHPYLNQSKLLDFCKSKDIVLVAHSALGTQRHKLWVDPNSPVLLEDPVLCALAKKHKRTP 252
Query: 677 AQVLIRYQIDRGNIXI 724
A + +RYQ+ RG + +
Sbjct: 253 ALIALRYQLQRGVVVL 268
>AB031085-1|BAA92885.1| 323|Homo sapiens dihydrodiol dehydrogenase
4 protein.
Length = 323
Score = 192 bits (467), Expect = 4e-48
Identities = 91/196 (46%), Positives = 128/196 (65%), Gaps = 3/196 (1%)
Frame = +2
Query: 146 SCKREDLFITSKLWNTFHRPDLXRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTD 325
S KRED+F TSKLW TF +P + + ALE SL+ L +DY+DLYL+H+P A K + P D
Sbjct: 73 SVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALKPGETPLPKD 132
Query: 326 ADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASV--KPVTNQVE 499
+GK+ F VD TW+ +E GL +S+GVSNFN +QL+ IL+ + KPV NQVE
Sbjct: 133 ENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILNKPGLKYKPVCNQVE 192
Query: 500 CHPXLNQKRLKQFCEDRDIMITAYSPLGSP-DRPWAKPGDPQLMEDPKLKEIADRLGKTV 676
CHP LNQ +L FC+ +DI++ A+S LG+ + W P P L+EDP L +A + +T
Sbjct: 193 CHPYLNQSKLLDFCKSKDIVLVAHSALGTQRHKLWVDPNSPVLLEDPVLCALAKKHKRTP 252
Query: 677 AQVLIRYQIDRGNIXI 724
A + +RYQ+ RG + +
Sbjct: 253 ALIALRYQLQRGVVVL 268
>BC020744-1|AAH20744.1| 323|Homo sapiens aldo-keto reductase family
1, member C4 (chlordecone reductase; 3-alpha hydroxy
protein.
Length = 323
Score = 191 bits (466), Expect = 5e-48
Identities = 91/196 (46%), Positives = 128/196 (65%), Gaps = 3/196 (1%)
Frame = +2
Query: 146 SCKREDLFITSKLWNTFHRPDLXRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTD 325
S KRED+F TSKLW TF +P + + ALE SL+ L +DY+DLYL+H+P A K + P D
Sbjct: 73 SVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALKPGETPLPKD 132
Query: 326 ADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASV--KPVTNQVE 499
+GK+ F VD TW+ +E GL +S+GVSNFN +QL+ IL+ + KPV NQVE
Sbjct: 133 ENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNYRQLEMILNKPGLKYKPVCNQVE 192
Query: 500 CHPXLNQKRLKQFCEDRDIMITAYSPLGSP-DRPWAKPGDPQLMEDPKLKEIADRLGKTV 676
CHP LNQ +L FC+ +DI++ A+S LG+ + W P P L+EDP L +A + +T
Sbjct: 193 CHPYLNQSKLLDFCKSKDIVLVAHSALGTQRHKLWVDPNSPVLLEDPVLCALAKKHKRTP 252
Query: 677 AQVLIRYQIDRGNIXI 724
A + +RYQ+ RG + +
Sbjct: 253 ALIALRYQLQRGVVVL 268
>AL355303-2|CAI14202.1| 323|Homo sapiens aldo-keto reductase family
1, member C4 (chlordecone reductase; 3-alpha hydroxy
protein.
Length = 323
Score = 191 bits (466), Expect = 5e-48
Identities = 91/196 (46%), Positives = 128/196 (65%), Gaps = 3/196 (1%)
Frame = +2
Query: 146 SCKREDLFITSKLWNTFHRPDLXRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTD 325
S KRED+F TSKLW TF +P + + ALE SL+ L +DY+DLYL+H+P A K + P D
Sbjct: 73 SVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALKPGETPLPKD 132
Query: 326 ADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASV--KPVTNQVE 499
+GK+ F VD TW+ +E GL +S+GVSNFN +QL+ IL+ + KPV NQVE
Sbjct: 133 ENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILNKPGLKYKPVCNQVE 192
Query: 500 CHPXLNQKRLKQFCEDRDIMITAYSPLGSP-DRPWAKPGDPQLMEDPKLKEIADRLGKTV 676
CHP LNQ +L FC+ +DI++ A+S LG+ + W P P L+EDP L +A + +T
Sbjct: 193 CHPYLNQSKLLDFCKSKDIVLVAHSALGTQRHKLWVDPNSPVLLEDPVLCALAKKHKQTP 252
Query: 677 AQVLIRYQIDRGNIXI 724
A + +RYQ+ RG + +
Sbjct: 253 ALIALRYQLQRGVVVL 268
>AB209017-1|BAD92254.1| 286|Homo sapiens aldo-keto reductase family
1, member C2 variant protein.
Length = 286
Score = 191 bits (465), Expect = 7e-48
Identities = 90/175 (51%), Positives = 119/175 (68%), Gaps = 3/175 (1%)
Frame = +2
Query: 146 SCKREDLFITSKLWNTFHRPDLXRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTD 325
S KRED+F TSKLW+ HRP+L R ALE SL+NL +DY+DLYLIH+P + K + + P D
Sbjct: 86 SVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKD 145
Query: 326 ADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASV--KPVTNQVE 499
+GKI F VD TW+A+E GL +S+GVSNFN + L+ IL+ + KPV NQVE
Sbjct: 146 ENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKYKPVCNQVE 205
Query: 500 CHPXLNQKRLKQFCEDRDIMITAYSPLGS-PDRPWAKPGDPQLMEDPKLKEIADR 661
CHP NQ++L FC+ +DI++ AYS LGS + PW P P L+EDP L +A +
Sbjct: 206 CHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKK 260
>Z28339-1|CAA82193.1| 326|Homo sapiens delta 4-3-oxosteroid 5
beta-reductase protein.
Length = 326
Score = 190 bits (464), Expect = 9e-48
Identities = 91/196 (46%), Positives = 126/196 (64%), Gaps = 3/196 (1%)
Frame = +2
Query: 152 KREDLFITSKLWNTFHRPDLXRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTDAD 331
+RED+F KLW T H P++ R LE +LR L +DY+DLY+I P A+K D I+P D +
Sbjct: 78 RREDIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLYIIEVPMAFKPGDEIYPRDEN 137
Query: 332 GKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASV--KPVTNQVECH 505
GK + + TW+A+E GLV+SLGVSNFN +QL+ IL+ + KPV+NQVECH
Sbjct: 138 GKWLYHKSNLCATWEAMEACKDAGLVKSLGVSNFNRRQLELILNKPGLKHKPVSNQVECH 197
Query: 506 PXLNQKRLKQFCEDRDIMITAYSPLGSPDRP-WAKPGDPQLMEDPKLKEIADRLGKTVAQ 682
P Q +L +FC+ DI+ITAYSPLG+ P W P L++D L + R KT AQ
Sbjct: 198 PYFTQPKLLKFCQQHDIVITAYSPLGTSRNPIWVNVSSPPLLKDALLNSLGKRYNKTAAQ 257
Query: 683 VLIRYQIDRGNIXIPE 730
+++R+ I RG + IP+
Sbjct: 258 IVLRFNIQRGVVVIPK 273
>BC130627-1|AAI30628.1| 326|Homo sapiens aldo-keto reductase family
1, member D1 (delta 4-3-ketosteroid-5-beta-reductase
protein.
Length = 326
Score = 190 bits (464), Expect = 9e-48
Identities = 91/196 (46%), Positives = 126/196 (64%), Gaps = 3/196 (1%)
Frame = +2
Query: 152 KREDLFITSKLWNTFHRPDLXRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTDAD 331
+RED+F KLW T H P++ R LE +LR L +DY+DLY+I P A+K D I+P D +
Sbjct: 78 RREDIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLYIIEVPMAFKPGDEIYPRDEN 137
Query: 332 GKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASV--KPVTNQVECH 505
GK + + TW+A+E GLV+SLGVSNFN +QL+ IL+ + KPV+NQVECH
Sbjct: 138 GKWLYHKSNLCATWEAMEACKDAGLVKSLGVSNFNRRQLELILNKPGLKHKPVSNQVECH 197
Query: 506 PXLNQKRLKQFCEDRDIMITAYSPLGSPDRP-WAKPGDPQLMEDPKLKEIADRLGKTVAQ 682
P Q +L +FC+ DI+ITAYSPLG+ P W P L++D L + R KT AQ
Sbjct: 198 PYFTQPKLLKFCQQHDIVITAYSPLGTSRNPIWVNVSSPPLLKDALLNSLGKRYNKTAAQ 257
Query: 683 VLIRYQIDRGNIXIPE 730
+++R+ I RG + IP+
Sbjct: 258 IVLRFNIQRGVVVIPK 273
>BC130625-1|AAI30626.1| 326|Homo sapiens aldo-keto reductase family
1, member D1 (delta 4-3-ketosteroid-5-beta-reductase
protein.
Length = 326
Score = 190 bits (464), Expect = 9e-48
Identities = 91/196 (46%), Positives = 126/196 (64%), Gaps = 3/196 (1%)
Frame = +2
Query: 152 KREDLFITSKLWNTFHRPDLXRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTDAD 331
+RED+F KLW T H P++ R LE +LR L +DY+DLY+I P A+K D I+P D +
Sbjct: 78 RREDIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLYIIEVPMAFKPGDEIYPRDEN 137
Query: 332 GKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASV--KPVTNQVECH 505
GK + + TW+A+E GLV+SLGVSNFN +QL+ IL+ + KPV+NQVECH
Sbjct: 138 GKWLYHKSNLCATWEAMEACKDAGLVKSLGVSNFNRRQLELILNKPGLKHKPVSNQVECH 197
Query: 506 PXLNQKRLKQFCEDRDIMITAYSPLGSPDRP-WAKPGDPQLMEDPKLKEIADRLGKTVAQ 682
P Q +L +FC+ DI+ITAYSPLG+ P W P L++D L + R KT AQ
Sbjct: 198 PYFTQPKLLKFCQQHDIVITAYSPLGTSRNPIWVNVSSPPLLKDALLNSLGKRYNKTAAQ 257
Query: 683 VLIRYQIDRGNIXIPE 730
+++R+ I RG + IP+
Sbjct: 258 IVLRFNIQRGVVVIPK 273
>AF283659-1|AAG39381.1| 326|Homo sapiens 5-beta steroid reductase
protein.
Length = 326
Score = 190 bits (464), Expect = 9e-48
Identities = 91/196 (46%), Positives = 126/196 (64%), Gaps = 3/196 (1%)
Frame = +2
Query: 152 KREDLFITSKLWNTFHRPDLXRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTDAD 331
+RED+F KLW T H P++ R LE +LR L +DY+DLY+I P A+K D I+P D +
Sbjct: 78 RREDIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLYIIEVPMAFKPGDEIYPRDEN 137
Query: 332 GKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASV--KPVTNQVECH 505
GK + + TW+A+E GLV+SLGVSNFN +QL+ IL+ + KPV+NQVECH
Sbjct: 138 GKWLYHKSNLCATWEAMEACKDAGLVKSLGVSNFNRRQLELILNKPGLKHKPVSNQVECH 197
Query: 506 PXLNQKRLKQFCEDRDIMITAYSPLGSPDRP-WAKPGDPQLMEDPKLKEIADRLGKTVAQ 682
P Q +L +FC+ DI+ITAYSPLG+ P W P L++D L + R KT AQ
Sbjct: 198 PYFTQPKLLKFCQQHDIVITAYSPLGTSRNPIWVNVSSPPLLKDALLNSLGKRYNKTAAQ 257
Query: 683 VLIRYQIDRGNIXIPE 730
+++R+ I RG + IP+
Sbjct: 258 IVLRFNIQRGVVVIPK 273
>BC002862-1|AAH02862.1| 307|Homo sapiens AKR1CL2 protein protein.
Length = 307
Score = 173 bits (421), Expect = 1e-42
Identities = 94/213 (44%), Positives = 127/213 (59%), Gaps = 21/213 (9%)
Frame = +2
Query: 152 KREDLFITSKLWNTFHRPDLXRGALEVSLRNLNIDYLDLYLIHWPQAYKE---------D 304
+REDLFI +KLW T H+ L A SL+ L ++YLDLYLIHWP +K
Sbjct: 60 RREDLFIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPMGFKPPHPEWIMSCS 119
Query: 305 DAIF----------PTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQR 454
+ F P D + SD D++DTW+A+E LV GLV+++GVSNFN +QL+R
Sbjct: 120 ELSFCLSHPRVQDLPLDESNMVIPSDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQLER 179
Query: 455 ILDNASV--KPVTNQVECHPXLNQKRLKQFCEDRDIMITAYSPLGSPDRPWAKPGDPQLM 628
+L+ + KP+TNQ+ECHP L QK L FC+ RD+ +TAY PLG L+
Sbjct: 180 LLNKPGLRFKPLTNQIECHPYLTQKNLISFCQSRDVSVTAYRPLGGSCE------GVDLI 233
Query: 629 EDPKLKEIADRLGKTVAQVLIRYQIDRGNIXIP 727
++P +K IA GK+ AQ+LIR+QI R I IP
Sbjct: 234 DNPVIKRIAKEHGKSPAQILIRFQIQRNVIVIP 266
>AF263242-1|AAK58523.1| 320|Homo sapiens aldo-keto reductase
loopADR protein.
Length = 320
Score = 173 bits (421), Expect = 1e-42
Identities = 94/213 (44%), Positives = 127/213 (59%), Gaps = 21/213 (9%)
Frame = +2
Query: 152 KREDLFITSKLWNTFHRPDLXRGALEVSLRNLNIDYLDLYLIHWPQAYKE---------D 304
+REDLFI +KLW T H+ L A SL+ L ++YLDLYLIHWP +K
Sbjct: 60 RREDLFIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPMGFKPPHPEWIMSCS 119
Query: 305 DAIF----------PTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQR 454
+ F P D + SD D++DTW+A+E LV GLV+++GVSNFN +QL+R
Sbjct: 120 ELSFCLSHPRVQDLPLDESNMVIPSDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQLER 179
Query: 455 ILDNASV--KPVTNQVECHPXLNQKRLKQFCEDRDIMITAYSPLGSPDRPWAKPGDPQLM 628
+L+ + KP+TNQ+ECHP L QK L FC+ RD+ +TAY PLG L+
Sbjct: 180 LLNKPGLRFKPLTNQIECHPYLTQKNLISFCQSRDVSVTAYRPLGGSCE------GVDLI 233
Query: 629 EDPKLKEIADRLGKTVAQVLIRYQIDRGNIXIP 727
++P +K IA GK+ AQ+LIR+QI R I IP
Sbjct: 234 DNPVIKRIAKEHGKSPAQILIRFQIQRNVIVIP 266
>AB055603-1|BAC54568.1| 307|Homo sapiens aldo-keto reductase
related protein 4 protein.
Length = 307
Score = 173 bits (421), Expect = 1e-42
Identities = 94/213 (44%), Positives = 127/213 (59%), Gaps = 21/213 (9%)
Frame = +2
Query: 152 KREDLFITSKLWNTFHRPDLXRGALEVSLRNLNIDYLDLYLIHWPQAYKE---------D 304
+REDLFI +KLW T H+ L A SL+ L ++YLDLYLIHWP +K
Sbjct: 60 RREDLFIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPMGFKPPHPEWIMSCS 119
Query: 305 DAIF----------PTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQR 454
+ F P D + SD D++DTW+A+E LV GLV+++GVSNFN +QL+R
Sbjct: 120 ELSFCLSHPRVQDLPLDESNMVIPSDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQLER 179
Query: 455 ILDNASV--KPVTNQVECHPXLNQKRLKQFCEDRDIMITAYSPLGSPDRPWAKPGDPQLM 628
+L+ + KP+TNQ+ECHP L QK L FC+ RD+ +TAY PLG L+
Sbjct: 180 LLNKPGLRFKPLTNQIECHPYLTQKNLISFCQSRDVSVTAYRPLGGSCE------GVDLI 233
Query: 629 EDPKLKEIADRLGKTVAQVLIRYQIDRGNIXIP 727
++P +K IA GK+ AQ+LIR+QI R I IP
Sbjct: 234 DNPVIKRIAKEHGKSPAQILIRFQIQRNVIVIP 266
>AL391427-2|CAI14727.1| 302|Homo sapiens aldo-keto reductase family
1, member C-like 1 protein.
Length = 302
Score = 136 bits (328), Expect = 3e-31
Identities = 81/194 (41%), Positives = 111/194 (57%), Gaps = 3/194 (1%)
Frame = +2
Query: 152 KREDLFITSKLWNTFHRPDLXRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDA-IFPTDA 328
KRE++F T KLW TF R +L ALE SL+ L DY+DL++IH P A K+ + P DA
Sbjct: 78 KREEIFYTIKLWATFFRAELVHPALERSLKKLGPDYVDLFIIHVPFAMKQPGKELLPKDA 137
Query: 329 DGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPVTNQV-ECH 505
G+I V+ DTW+ LE ++ N L+ KP NQV ECH
Sbjct: 138 SGEIILETVELCDTWE-LELIL-------------NKPGLR-------YKPTCNQVVECH 176
Query: 506 PXLNQKRLKQFCEDRDIMITAYSPLGSP-DRPWAKPGDPQLMEDPKLKEIADRLGKTVAQ 682
P LNQ +L +FC+ +DI++ AYS LGS D W P P L+E+P LK IA + ++ Q
Sbjct: 177 PYLNQSKLLEFCKSKDIVLVAYSALGSQRDPQWVDPDCPHLLEEPILKSIAKKHSRSPGQ 236
Query: 683 VLIRYQIDRGNIXI 724
V +RYQ+ RG + +
Sbjct: 237 VALRYQLQRGVVVL 250
Score = 32.7 bits (71), Expect = 3.6
Identities = 13/28 (46%), Positives = 20/28 (71%)
Frame = +3
Query: 729 KSVTKSRIASNFDVFDFKLSLQDVALID 812
KS ++ RI NF +FDF+L+ +D+ ID
Sbjct: 252 KSFSQERIKENFQIFDFELTPEDMKAID 279
>AL355303-1|CAI14201.1| 302|Homo sapiens aldo-keto reductase family
1, member C-like 1 protein.
Length = 302
Score = 136 bits (328), Expect = 3e-31
Identities = 81/194 (41%), Positives = 111/194 (57%), Gaps = 3/194 (1%)
Frame = +2
Query: 152 KREDLFITSKLWNTFHRPDLXRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDA-IFPTDA 328
KRE++F T KLW TF R +L ALE SL+ L DY+DL++IH P A K+ + P DA
Sbjct: 78 KREEIFYTIKLWATFFRAELVHPALERSLKKLGPDYVDLFIIHVPFAMKQPGKELLPKDA 137
Query: 329 DGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPVTNQV-ECH 505
G+I V+ DTW+ LE ++ N L+ KP NQV ECH
Sbjct: 138 SGEIILETVELCDTWE-LELIL-------------NKPGLR-------YKPTCNQVVECH 176
Query: 506 PXLNQKRLKQFCEDRDIMITAYSPLGSP-DRPWAKPGDPQLMEDPKLKEIADRLGKTVAQ 682
P LNQ +L +FC+ +DI++ AYS LGS D W P P L+E+P LK IA + ++ Q
Sbjct: 177 PYLNQSKLLEFCKSKDIVLVAYSALGSQRDPQWVDPDCPHLLEEPILKSIAKKHSRSPGQ 236
Query: 683 VLIRYQIDRGNIXI 724
V +RYQ+ RG + +
Sbjct: 237 VALRYQLQRGVVVL 250
Score = 32.7 bits (71), Expect = 3.6
Identities = 13/28 (46%), Positives = 20/28 (71%)
Frame = +3
Query: 729 KSVTKSRIASNFDVFDFKLSLQDVALID 812
KS ++ RI NF +FDF+L+ +D+ ID
Sbjct: 252 KSFSQERIKENFQIFDFELTPEDMKAID 279
>AK058142-1|BAB71682.1| 146|Homo sapiens protein ( Homo sapiens
cDNA FLJ25413 fis, clone TST03402, highly similar to
3-OXO-5-BETA-STEROID 4-DEHYDROGENASE (EC 1.3.99.6). ).
Length = 146
Score = 110 bits (264), Expect = 2e-23
Identities = 56/122 (45%), Positives = 78/122 (63%), Gaps = 3/122 (2%)
Frame = +2
Query: 290 AYKEDDAIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNA 469
A+K D I+P D +GK + + TW+A+E GLV+SLGVSNFN +QL+ IL+
Sbjct: 2 AFKPGDEIYPRDENGKWLYHKSNLCATWEAMEACKDAGLVKSLGVSNFNRRQLELILNKP 61
Query: 470 SVK--PVTNQVECHPXLNQKRLKQFCEDRDIMITAYSPLGSPDRP-WAKPGDPQLMEDPK 640
+K PV+NQVECHP Q +L +FC+ DI+ITAYSPLG+ P W + L++ P
Sbjct: 62 GLKHKPVSNQVECHPYFTQPKLLKFCQQHDIVITAYSPLGTSRNPIWRQLHKLALLDLPI 121
Query: 641 LK 646
L+
Sbjct: 122 LR 123
>AB040821-1|BAC54566.1| 263|Homo sapiens aldo-keto reductase
related protein 2 protein.
Length = 263
Score = 106 bits (254), Expect = 2e-22
Identities = 58/136 (42%), Positives = 81/136 (59%), Gaps = 21/136 (15%)
Frame = +2
Query: 152 KREDLFITSKLWNTFHRPDLXRGALEVSLRNLNIDYLDLYLIHWPQAYKE---------D 304
+REDLFI +KLW T H+ L A SL+ L ++YLDLYLIHWP +K
Sbjct: 60 RREDLFIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPMGFKPPHPEWIMSCS 119
Query: 305 DAIF----------PTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQR 454
+ F P D + SD D++DTW+A+E LV GLV+++GVSNFN +QL+R
Sbjct: 120 ELSFCLSHPRVQDLPLDESNMVIPSDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQLER 179
Query: 455 ILDNASV--KPVTNQV 496
+L+ + KP+TNQ+
Sbjct: 180 LLNKPGLRFKPLTNQI 195
>AB040820-1|BAC54565.1| 250|Homo sapiens aldo-keto reductase
related protein 1 protein.
Length = 250
Score = 106 bits (254), Expect = 2e-22
Identities = 58/136 (42%), Positives = 81/136 (59%), Gaps = 21/136 (15%)
Frame = +2
Query: 152 KREDLFITSKLWNTFHRPDLXRGALEVSLRNLNIDYLDLYLIHWPQAYKE---------D 304
+REDLFI +KLW T H+ L A SL+ L ++YLDLYLIHWP +K
Sbjct: 60 RREDLFIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPMGFKPPHPEWIMSCS 119
Query: 305 DAIF----------PTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQR 454
+ F P D + SD D++DTW+A+E LV GLV+++GVSNFN +QL+R
Sbjct: 120 ELSFCLSHPRVQDLPLDESNMVIPSDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQLER 179
Query: 455 ILDNASV--KPVTNQV 496
+L+ + KP+TNQ+
Sbjct: 180 LLNKPGLRFKPLTNQI 195
>AL355480-2|CAI22458.1| 147|Homo sapiens aldo-keto reductase family
1, member A1 (aldehydela) protein.
Length = 147
Score = 94.3 bits (224), Expect = 1e-18
Identities = 40/76 (52%), Positives = 53/76 (69%)
Frame = +2
Query: 155 REDLFITSKLWNTFHRPDLXRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTDADG 334
RE+LF+TSKLWNT H P+ AL +L +L ++YLDLYL+HWP A++ D FP +ADG
Sbjct: 72 REELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDNPFPKNADG 131
Query: 335 KIQFSDVDYVDTWKAL 382
I + Y +TWKAL
Sbjct: 132 TICYDSTHYKETWKAL 147
>AB040822-1|BAC54567.1| 222|Homo sapiens aldo-keto reductase
related protein 3 protein.
Length = 222
Score = 64.1 bits (149), Expect = 1e-09
Identities = 37/96 (38%), Positives = 49/96 (51%), Gaps = 19/96 (19%)
Frame = +2
Query: 152 KREDLFITSKLWNTFHRPDLXRGALEVSLRNLNIDYLDLYLIHWPQAYKE---------D 304
+REDLFI +KLW T H+ L A SL+ L ++YLDLYLIHWP +K
Sbjct: 60 RREDLFIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPMGFKPPHPEWIMSCS 119
Query: 305 DAIF----------PTDADGKIQFSDVDYVDTWKAL 382
+ F P D + SD D++DTW+ L
Sbjct: 120 ELSFCLSHPRVQDLPLDESNMVIPSDTDFLDTWEIL 155
>AB037902-1|BAA92887.1| 130|Homo sapiens truncated aldo-keto
reductase protein.
Length = 130
Score = 62.5 bits (145), Expect = 4e-09
Identities = 24/45 (53%), Positives = 35/45 (77%)
Frame = +2
Query: 152 KREDLFITSKLWNTFHRPDLXRGALEVSLRNLNIDYLDLYLIHWP 286
KR+D+F T+K+W TF RP+L + LE+SL+ L + Y+DLYL H+P
Sbjct: 76 KRKDIFYTTKVWGTFSRPELVQRGLEMSLKKLQLSYMDLYLFHFP 120
>AB028065-1|BAA88489.1| 67|Homo sapiens prostaglandin F synthase
protein.
Length = 67
Score = 61.3 bits (142), Expect = 9e-09
Identities = 30/65 (46%), Positives = 42/65 (64%), Gaps = 2/65 (3%)
Frame = +2
Query: 305 DAIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASV--K 478
+ + PTD +GK+ F VD TW+A+E GL +S+GVSNFN +QL+ IL+ + K
Sbjct: 3 EELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYK 62
Query: 479 PVTNQ 493
PV NQ
Sbjct: 63 PVCNQ 67
>BC101205-1|AAI01206.1| 129|Homo sapiens aldo-keto reductase family
1, member C-like 1 protein.
Length = 129
Score = 57.6 bits (133), Expect = 1e-07
Identities = 27/49 (55%), Positives = 34/49 (69%)
Frame = +2
Query: 152 KREDLFITSKLWNTFHRPDLXRGALEVSLRNLNIDYLDLYLIHWPQAYK 298
KRE++F T KLW TF R +L ALE SL+ L DY+DL++IH P A K
Sbjct: 78 KREEIFYTIKLWATFFRAELVHPALERSLKKLGPDYVDLFIIHVPFAMK 126
>BC101204-1|AAI01205.1| 129|Homo sapiens aldo-keto reductase family
1, member C-like 1 protein.
Length = 129
Score = 57.6 bits (133), Expect = 1e-07
Identities = 27/49 (55%), Positives = 34/49 (69%)
Frame = +2
Query: 152 KREDLFITSKLWNTFHRPDLXRGALEVSLRNLNIDYLDLYLIHWPQAYK 298
KRE++F T KLW TF R +L ALE SL+ L DY+DL++IH P A K
Sbjct: 78 KREEIFYTIKLWATFFRAELVHPALERSLKKLGPDYVDLFIIHVPFAMK 126
>AK131335-1|BAD18494.1| 129|Homo sapiens protein ( Homo sapiens
cDNA FLJ16347 fis, clone TESTI2036288, moderately
similar to PROSTAGLANDIN-F SYNTHASE 1 (EC 1.1.1.188). ).
Length = 129
Score = 57.6 bits (133), Expect = 1e-07
Identities = 27/49 (55%), Positives = 34/49 (69%)
Frame = +2
Query: 152 KREDLFITSKLWNTFHRPDLXRGALEVSLRNLNIDYLDLYLIHWPQAYK 298
KRE++F T KLW TF R +L ALE SL+ L DY+DL++IH P A K
Sbjct: 78 KREEIFYTIKLWATFFRAELVHPALERSLKKLGPDYVDLFIIHVPFAMK 126
>AB037905-2|BAA92890.1| 45|Homo sapiens truncated aldo-keto
reductase protein.
Length = 45
Score = 48.4 bits (110), Expect = 7e-05
Identities = 18/35 (51%), Positives = 26/35 (74%)
Frame = +2
Query: 182 LWNTFHRPDLXRGALEVSLRNLNIDYLDLYLIHWP 286
+W TF RP+L + LE+SL+ L + Y+DLYL H+P
Sbjct: 1 VWGTFSRPELVQRGLEMSLKKLQLSYMDLYLFHFP 35
>AF044961-1|AAC15671.1| 85|Homo sapiens aldose reductase-related
protein protein.
Length = 85
Score = 39.9 bits (89), Expect = 0.024
Identities = 19/37 (51%), Positives = 23/37 (62%)
Frame = +3
Query: 726 PKSVTKSRIASNFDVFDFKLSLQDVALIDXHRLXWAA 836
PKSVT +RI N VFDFKLS +++A I W A
Sbjct: 31 PKSVTPARIVENIQVFDFKLSDEEMATILSFNRNWRA 67
Score = 39.1 bits (87), Expect = 0.042
Identities = 19/32 (59%), Positives = 23/32 (71%)
Frame = +2
Query: 635 PKLKEIADRLGKTVAQVLIRYQIDRGNIXIPE 730
PK+KEIA + KT AQVLIR+ I R I IP+
Sbjct: 1 PKIKEIAAKHKKTAAQVLIRFHIQRNVIVIPK 32
>L35546-1|AAA65028.1| 274|Homo sapiens gamma-glutamylcysteine
synthetase light subunit protein.
Length = 274
Score = 33.9 bits (74), Expect = 1.6
Identities = 16/42 (38%), Positives = 26/42 (61%)
Frame = +2
Query: 371 WKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPVTNQV 496
W+ LE LV + ++G S+ + QL+++ A VKP +NQV
Sbjct: 147 WEELENLVQSKKIVAIGTSDLDKTQLEQLYQWAQVKPNSNQV 188
>CR541833-1|CAG46632.1| 274|Homo sapiens GCLM protein.
Length = 274
Score = 33.9 bits (74), Expect = 1.6
Identities = 16/42 (38%), Positives = 26/42 (61%)
Frame = +2
Query: 371 WKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPVTNQV 496
W+ LE LV + ++G S+ + QL+++ A VKP +NQV
Sbjct: 147 WEELENLVQSKKIVAIGTSDLDKTQLEQLYQWAQVKPNSNQV 188
>BC041809-1|AAH41809.1| 274|Homo sapiens glutamate-cysteine ligase,
modifier subunit protein.
Length = 274
Score = 33.9 bits (74), Expect = 1.6
Identities = 16/42 (38%), Positives = 26/42 (61%)
Frame = +2
Query: 371 WKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPVTNQV 496
W+ LE LV + ++G S+ + QL+++ A VKP +NQV
Sbjct: 147 WEELENLVQSKKIVAIGTSDLDKTQLEQLYQWAQVKPNSNQV 188
>AY773965-1|AAV28733.1| 274|Homo sapiens glutamate-cysteine ligase,
modifier subunit protein.
Length = 274
Score = 33.9 bits (74), Expect = 1.6
Identities = 16/42 (38%), Positives = 26/42 (61%)
Frame = +2
Query: 371 WKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPVTNQV 496
W+ LE LV + ++G S+ + QL+++ A VKP +NQV
Sbjct: 147 WEELENLVQSKKIVAIGTSDLDKTQLEQLYQWAQVKPNSNQV 188
>AL117351-10|CAI22976.1| 274|Homo sapiens glutamate-cysteine
ligase, modifier subunit protein.
Length = 274
Score = 33.9 bits (74), Expect = 1.6
Identities = 16/42 (38%), Positives = 26/42 (61%)
Frame = +2
Query: 371 WKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPVTNQV 496
W+ LE LV + ++G S+ + QL+++ A VKP +NQV
Sbjct: 147 WEELENLVQSKKIVAIGTSDLDKTQLEQLYQWAQVKPNSNQV 188
>AL049796-2|CAI21813.1| 274|Homo sapiens glutamate-cysteine ligase,
modifier subunit protein.
Length = 274
Score = 33.9 bits (74), Expect = 1.6
Identities = 16/42 (38%), Positives = 26/42 (61%)
Frame = +2
Query: 371 WKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPVTNQV 496
W+ LE LV + ++G S+ + QL+++ A VKP +NQV
Sbjct: 147 WEELENLVQSKKIVAIGTSDLDKTQLEQLYQWAQVKPNSNQV 188
>AK025955-1|BAB15295.1| 458|Homo sapiens protein ( Homo sapiens
cDNA: FLJ22302 fis, clone HRC04795. ).
Length = 458
Score = 33.5 bits (73), Expect = 2.1
Identities = 16/44 (36%), Positives = 18/44 (40%)
Frame = -1
Query: 519 WFKXGWHSTWLVTGFTEALSSILWSCFELKFETPRLRTSPWHTR 388
W+ GW S L TGF LW+ L TP R W R
Sbjct: 59 WYSFGWESQLLETGFLGIFLCPLWTLSRLPQHTPTSRIVLWGFR 102
>AK022743-1|BAB14218.1| 567|Homo sapiens protein ( Homo sapiens
cDNA FLJ12681 fis, clone NT2RM4002446. ).
Length = 567
Score = 33.5 bits (73), Expect = 2.1
Identities = 16/44 (36%), Positives = 18/44 (40%)
Frame = -1
Query: 519 WFKXGWHSTWLVTGFTEALSSILWSCFELKFETPRLRTSPWHTR 388
W+ GW S L TGF LW+ L TP R W R
Sbjct: 168 WYSFGWESQLLETGFLGIFLCPLWTLSRLPQHTPTSRIVLWGFR 211
>AE006465-5|AAK61259.1| 567|Homo sapiens possible integral membrane
protein.
Length = 567
Score = 33.5 bits (73), Expect = 2.1
Identities = 16/44 (36%), Positives = 18/44 (40%)
Frame = -1
Query: 519 WFKXGWHSTWLVTGFTEALSSILWSCFELKFETPRLRTSPWHTR 388
W+ GW S L TGF LW+ L TP R W R
Sbjct: 168 WYSFGWESQLLETGFLGIFLCPLWTLSRLPQHTPTSRIVLWGFR 211
>AB075873-1|BAD38655.1| 563|Homo sapiens putative protein product
of HMFN1876 protein.
Length = 563
Score = 33.5 bits (73), Expect = 2.1
Identities = 16/44 (36%), Positives = 18/44 (40%)
Frame = -1
Query: 519 WFKXGWHSTWLVTGFTEALSSILWSCFELKFETPRLRTSPWHTR 388
W+ GW S L TGF LW+ L TP R W R
Sbjct: 164 WYSFGWESQLLETGFLGIFLCPLWTLSRLPQHTPTSRIVLWGFR 207
>BC010738-1|AAH10738.2| 490|Homo sapiens TMEM112 protein protein.
Length = 490
Score = 33.1 bits (72), Expect = 2.8
Identities = 16/44 (36%), Positives = 18/44 (40%)
Frame = -1
Query: 519 WFKXGWHSTWLVTGFTEALSSILWSCFELKFETPRLRTSPWHTR 388
W+ GW S L TGF LW+ L TP R W R
Sbjct: 91 WYSFGWESQLLETGFLGIFLCPLWTLSRLPQHTPTPRIVLWGFR 134
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 162,687,098
Number of Sequences: 237096
Number of extensions: 2958422
Number of successful extensions: 6431
Number of sequences better than 10.0: 105
Number of HSP's better than 10.0 without gapping: 5895
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 6300
length of database: 76,859,062
effective HSP length: 93
effective length of database: 54,809,134
effective search space used: 22690981476
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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