Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= 030723E4_B05_e322_03.seq
(1528 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_Q9NR45 Cluster: Sialic acid synthase; n=39; Coelomata|R... 238 3e-61
UniRef50_Q9VG74 Cluster: CG5232-PA; n=4; Diptera|Rep: CG5232-PA ... 190 6e-47
UniRef50_UPI0000D9DE3E Cluster: PREDICTED: similar to N-acetylne... 157 7e-37
UniRef50_Q07IS3 Cluster: N-acetylneuraminate synthase; n=1; Rhod... 156 2e-36
UniRef50_Q9RDX5 Cluster: N-acetylneuraminic acid condensing enzy... 136 2e-30
UniRef50_A6D0F9 Cluster: Sialic acid synthase; n=2; Gammaproteob... 135 3e-30
UniRef50_A6L7H8 Cluster: Sialic acid synthase; n=1; Bacteroides ... 128 3e-28
UniRef50_A0NMM3 Cluster: N-acylneuraminate-9-phosphate synthase;... 128 4e-28
UniRef50_Q74B32 Cluster: Polysaccharide biosynthesis protein, pu... 128 5e-28
UniRef50_Q04TT0 Cluster: N-acetyl neuraminic (Sialic) acid synth... 126 1e-27
UniRef50_Q58465 Cluster: Uncharacterized protein MJ1065; n=1; Me... 126 2e-27
UniRef50_Q1IMQ8 Cluster: N-acetylneuraminate synthase; n=16; Bac... 124 6e-27
UniRef50_A4FX91 Cluster: N-acylneuraminate-9-phosphate synthase;... 123 1e-26
UniRef50_Q0M1E8 Cluster: N-acylneuraminate-9-phosphate synthase;... 121 6e-26
UniRef50_A7DQW3 Cluster: N-acylneuraminate-9-phosphate synthase;... 120 1e-25
UniRef50_Q0IDR1 Cluster: N-acetylneuraminic acid condensing enzy... 112 2e-23
UniRef50_UPI00015B984F Cluster: UPI00015B984F related cluster; n... 110 8e-23
UniRef50_Q04TM5 Cluster: N-acetylneuraminic acid (Sialic acid) s... 110 1e-22
UniRef50_Q893U6 Cluster: N-acetylneuraminate synthase; n=1; Clos... 109 2e-22
UniRef50_A5MZ25 Cluster: Predicted polysaccharide biosynthesis p... 109 2e-22
UniRef50_Q3AZQ1 Cluster: N-acylneuraminate-9-phosphate synthase;... 108 4e-22
UniRef50_Q8A711 Cluster: Sialic acid synthase; n=1; Bacteroides ... 107 8e-22
UniRef50_Q0FYM0 Cluster: N-acylneuraminate-9-phosphate synthase;... 105 3e-21
UniRef50_Q2Y4J1 Cluster: NeuB family member; n=5; cellular organ... 105 3e-21
UniRef50_A4AP54 Cluster: N-acetylneuraminate synthase; n=3; cell... 104 5e-21
UniRef50_Q8DDZ7 Cluster: Sialic acid synthase; n=5; Bacteria|Rep... 103 9e-21
UniRef50_A7GGU3 Cluster: NeuB family protein; n=1; Clostridium b... 102 2e-20
UniRef50_Q4VKA5 Cluster: NeuNAc condensing enzyme; n=54; cellula... 101 7e-20
UniRef50_Q3XXA4 Cluster: N-acetylneuraminate synthase; n=1; Ente... 100 1e-19
UniRef50_A3V3D1 Cluster: Polysialic acid capsule biosynthesis pr... 100 2e-19
UniRef50_Q73P39 Cluster: NeuB family protein; n=1; Treponema den... 99 4e-19
UniRef50_Q46675 Cluster: NeuB protein; n=8; Bacteria|Rep: NeuB p... 98 5e-19
UniRef50_Q0A628 Cluster: N-acylneuraminate-9-phosphate synthase;... 98 6e-19
UniRef50_Q04TP3 Cluster: N-acetylneuraminic acid (Sialic acid) s... 98 6e-19
UniRef50_Q8TJL5 Cluster: N-acetylneuraminic acid phosphate synth... 95 3e-18
UniRef50_Q9A4G6 Cluster: NeuB protein, putative; n=17; Bacteria|... 95 6e-18
UniRef50_Q1PVV9 Cluster: Similarity to N-acetyl neuramic acid sy... 94 1e-17
UniRef50_Q93NQ2 Cluster: NnaB; n=7; Bacteria|Rep: NnaB - Escheri... 91 7e-17
UniRef50_A0LYV7 Cluster: N-acetylneuraminate synthase; n=1; Gram... 91 7e-17
UniRef50_Q89HL9 Cluster: Blr5971 protein; n=1; Bradyrhizobium ja... 91 9e-17
UniRef50_Q12JI6 Cluster: N-acetylneuraminic acid synthase-like p... 91 9e-17
UniRef50_A3PE56 Cluster: Sialic acid synthase; n=1; Prochlorococ... 91 9e-17
UniRef50_Q2N2P7 Cluster: NeuB; n=7; Proteobacteria|Rep: NeuB - A... 90 1e-16
UniRef50_A2C5V5 Cluster: Sialic acid synthase; n=1; Prochlorococ... 90 1e-16
UniRef50_Q97H26 Cluster: Sialic acid synthase; n=14; cellular or... 89 3e-16
UniRef50_Q5R082 Cluster: Sialic acid synthase; n=47; Bacteria|Re... 88 5e-16
UniRef50_A4B2T9 Cluster: NeuB:Antifreeze-like protein; n=1; Alte... 88 5e-16
UniRef50_Q5QWT8 Cluster: Sialic acid synthase; n=14; Bacteria|Re... 88 7e-16
UniRef50_Q7NQV6 Cluster: N-acetylneuraminic acid synthase; n=7; ... 87 2e-15
UniRef50_A3Y8V9 Cluster: NeuB family protein; n=1; Marinomonas s... 87 2e-15
UniRef50_P39625 Cluster: Spore coat polysaccharide biosynthesis ... 87 2e-15
UniRef50_A4MIF1 Cluster: N-acylneuraminate-9-phosphate synthase;... 85 4e-15
UniRef50_A1RHT0 Cluster: N-acylneuraminate-9-phosphate synthase;... 85 4e-15
UniRef50_Q89HJ8 Cluster: Blr5992 protein; n=2; Proteobacteria|Re... 85 5e-15
UniRef50_Q18EL3 Cluster: Sialic acid synthase; n=1; Haloquadratu... 84 1e-14
UniRef50_Q7VHQ5 Cluster: Sialic acid synthase; n=6; Helicobacter... 83 1e-14
UniRef50_Q30V22 Cluster: N-acylneuraminate-9-phosphate synthase;... 83 1e-14
UniRef50_Q1GST3 Cluster: N-acylneuraminate-9-phosphate synthase;... 83 2e-14
UniRef50_Q7MPQ0 Cluster: Sialic acid synthase; n=3; Proteobacter... 81 6e-14
UniRef50_A6W187 Cluster: N-acylneuraminate-9-phosphate synthase;... 81 8e-14
UniRef50_A1WSD6 Cluster: N-acylneuraminate-9-phosphate synthase;... 77 1e-12
UniRef50_UPI0000384B44 Cluster: COG2089: Sialic acid synthase; n... 76 2e-12
UniRef50_A4U183 Cluster: N-acetylneuraminate synthase; n=1; Magn... 76 3e-12
UniRef50_Q3B0R9 Cluster: N-acylneuraminate-9-phosphate synthase;... 74 9e-12
UniRef50_Q0P8U0 Cluster: Pse synthetase; n=14; Campylobacter|Rep... 74 9e-12
UniRef50_A2BSE7 Cluster: Sialic acid synthase; n=1; Prochlorococ... 74 9e-12
UniRef50_Q726U8 Cluster: NeuB family protein; n=2; Desulfovibrio... 73 2e-11
UniRef50_A4U173 Cluster: NeuB; n=1; Magnetospirillum gryphiswald... 73 2e-11
UniRef50_A4BEM9 Cluster: Sialic acid synthase; n=1; Reinekea sp.... 73 3e-11
UniRef50_Q2BI17 Cluster: N-acetylneuraminate synthase; n=4; Bact... 72 3e-11
UniRef50_Q11RF6 Cluster: N-acetylneuraminic acid synthetase; n=2... 69 4e-10
UniRef50_Q0YTS4 Cluster: N-acylneuraminate-9-phosphate synthase;... 69 4e-10
UniRef50_Q2IZW6 Cluster: N-acetylneuraminate synthase; n=1; Rhod... 68 6e-10
UniRef50_O83573 Cluster: Spore coat polysaccharide biosynthesis ... 67 1e-09
UniRef50_Q0AN71 Cluster: N-acetylneuraminate synthase; n=1; Mari... 66 3e-09
UniRef50_Q8EC83 Cluster: Polysaccharide biosynthesis related-pro... 65 4e-09
UniRef50_A0LAB4 Cluster: N-acetylneuraminic acid synthase, N-ter... 64 9e-09
UniRef50_A7DQU2 Cluster: N-acylneuraminate-9-phosphate synthase;... 62 4e-08
UniRef50_Q2BJD7 Cluster: N-acetylneuraminic acid synthetase; n=1... 61 7e-08
UniRef50_Q319P5 Cluster: Putative spore coat polysaccharide bios... 51 7e-05
UniRef50_UPI0000E87B4B Cluster: putative N-acetyl neuramic acid ... 51 9e-05
UniRef50_Q0IDQ4 Cluster: NeuB family protein; n=1; Synechococcus... 51 9e-05
UniRef50_Q2AHF7 Cluster: Antifreeze-like; n=1; Halothermothrix o... 50 2e-04
UniRef50_A5W0I0 Cluster: N-acetylneuraminic acid synthase, N-ter... 49 4e-04
UniRef50_A5IGD9 Cluster: Spore coat polysaccharide biosynthesis ... 45 0.006
UniRef50_Q7NR94 Cluster: Probable spore coat polysaccharide bios... 44 0.011
UniRef50_Q88Z00 Cluster: Non-ribosomal peptide synthetase NpsB; ... 39 0.40
UniRef50_UPI0000F219ED Cluster: PREDICTED: hypothetical protein;... 38 0.92
UniRef50_A2ENS5 Cluster: Putative uncharacterized protein; n=1; ... 37 1.2
UniRef50_Q54FM7 Cluster: Putative uncharacterized protein; n=1; ... 36 2.8
UniRef50_UPI000038CA6C Cluster: COG5295: Autotransporter adhesin... 36 3.7
UniRef50_UPI0000E117D8 Cluster: Na(+)-translocating NADH-quinone... 35 4.9
UniRef50_A5AVR4 Cluster: Putative uncharacterized protein; n=1; ... 35 6.5
>UniRef50_Q9NR45 Cluster: Sialic acid synthase; n=39; Coelomata|Rep:
Sialic acid synthase - Homo sapiens (Human)
Length = 359
Score = 238 bits (582), Expect = 3e-61
Identities = 107/204 (52%), Positives = 145/204 (71%)
Frame = +3
Query: 261 LEVKITEDVKVGGNNPCFIIAEVGQNHQGDIGIAKQLIKAAKDAGASCVKFQKTCLKEKF 440
LE+++ VGG +PCFIIAE+GQNHQGD+ +AK++I+ AK+ GA C KFQK+ L+ KF
Sbjct: 3 LELELCPGRWVGGQHPCFIIAEIGQNHQGDLDVAKRMIRMAKECGADCAKFQKSELEFKF 62
Query: 441 TKKYLERSYDNHNSWGKTYGDHKKHLEFSESQYRELFKYAHEIGILFTASAMDMVSFDFL 620
+K LER Y + +SWGKTYG+HK+HLEFS QYREL +YA E+GI FTAS MD ++ +FL
Sbjct: 63 NRKALERPYTSKHSWGKTYGEHKRHLEFSHDQYRELQRYAEEVGIFFTASGMDEMAVEFL 122
Query: 621 VNLKVPFIKIGSGDSNNLLFLKYAASKKLPLIISTGMVDKSAVKTIYDIISSEHKQFCLL 800
L VPF K+GSGD+NN +L+ A K P++IS+GM +K +Y I+ + FC L
Sbjct: 123 HELNVPFFKVGSGDTNNFPYLEKTAKKGRPMVISSGMQSMDTMKQVYQIVKPLNPNFCFL 182
Query: 801 HXISAYPVPFEDCNLTVLQDYKIL 872
SAYP+ ED NL V+ +Y+ L
Sbjct: 183 QCTSAYPLQPEDVNLRVISEYQKL 206
>UniRef50_Q9VG74 Cluster: CG5232-PA; n=4; Diptera|Rep: CG5232-PA -
Drosophila melanogaster (Fruit fly)
Length = 372
Score = 190 bits (464), Expect = 6e-47
Identities = 92/182 (50%), Positives = 126/182 (69%), Gaps = 1/182 (0%)
Frame = +3
Query: 312 FIIAEVGQNHQGDIGIAKQLIKAAKDAGASCVKFQKTCLKEKFTKKYLERSYDNHNSWGK 491
+IIAE+GQNHQG + AK++I AK AG CVKFQK+ L KFT+ L+R Y + ++WGK
Sbjct: 16 YIIAEIGQNHQGCVETAKKMIWEAKKAGCHCVKFQKSDLPAKFTRSALDREYISDHAWGK 75
Query: 492 TYGDHKKHLEFSESQYRELFKYAHEIGILFTASAMDMVSFDFLVNLKVPFIKIGSGDSNN 671
TYG+HK++LEFS+ QY +L + E+ + FTASAMD S +FL L VPFIKIGSGD+NN
Sbjct: 76 TYGEHKEYLEFSKDQYLQLQAHCKELNVDFTASAMDERSLEFLSALNVPFIKIGSGDANN 135
Query: 672 LLFLKYAASKKLPLIISTGMVDKSAVKTIYDIISSEHKQ-FCLLHXISAYPVPFEDCNLT 848
LK AA+ LPL+ISTGM V+ I + K+ + L+H +S+YP +DC+L
Sbjct: 136 FPLLKKAANLNLPLVISTGMQTMQTVERIVQTMRESGKEDYALMHCVSSYPTDPKDCSLQ 195
Query: 849 VL 854
++
Sbjct: 196 LI 197
>UniRef50_UPI0000D9DE3E Cluster: PREDICTED: similar to
N-acetylneuraminic acid phosphate synthase; n=1; Macaca
mulatta|Rep: PREDICTED: similar to N-acetylneuraminic
acid phosphate synthase - Macaca mulatta
Length = 274
Score = 157 bits (381), Expect = 7e-37
Identities = 68/113 (60%), Positives = 89/113 (78%)
Frame = +3
Query: 261 LEVKITEDVKVGGNNPCFIIAEVGQNHQGDIGIAKQLIKAAKDAGASCVKFQKTCLKEKF 440
LE+++ VGG +PCFIIAE+GQNHQGD+ +AK++I+ AK+ GA C KFQK+ L+ KF
Sbjct: 3 LELELCPGRWVGGQHPCFIIAEIGQNHQGDLDVAKRMIRMAKECGADCAKFQKSELEFKF 62
Query: 441 TKKYLERSYDNHNSWGKTYGDHKKHLEFSESQYRELFKYAHEIGILFTASAMD 599
+K LER Y + +SWGKTYG+HK+HLEF+ QYREL +YA E+GI FTAS MD
Sbjct: 63 NRKALERPYTSKHSWGKTYGEHKRHLEFNHDQYRELQRYAEEVGIFFTASGMD 115
>UniRef50_Q07IS3 Cluster: N-acetylneuraminate synthase; n=1;
Rhodopseudomonas palustris BisA53|Rep:
N-acetylneuraminate synthase - Rhodopseudomonas
palustris (strain BisA53)
Length = 357
Score = 156 bits (378), Expect = 2e-36
Identities = 78/192 (40%), Positives = 112/192 (58%)
Frame = +3
Query: 291 VGGNNPCFIIAEVGQNHQGDIGIAKQLIKAAKDAGASCVKFQKTCLKEKFTKKYLERSYD 470
V NP F+IAEVG NHQGDI K + KAAK+AGA VK QK + FT + + YD
Sbjct: 12 VTDENPSFVIAEVGHNHQGDIEKCKAIFKAAKEAGADAVKIQKRDNRALFTAEMYDSHYD 71
Query: 471 NHNSWGKTYGDHKKHLEFSESQYRELFKYAHEIGILFTASAMDMVSFDFLVNLKVPFIKI 650
+ N++ TYG H++ LEF+ QY EL +Y ++ ILF ++A D S + L + +P KI
Sbjct: 72 SENAYAHTYGTHRECLEFNREQYLELKEYCKQLDILFFSTAFDEPSAELLEEIDMPGFKI 131
Query: 651 GSGDSNNLLFLKYAASKKLPLIISTGMVDKSAVKTIYDIISSEHKQFCLLHXISAYPVPF 830
SGD N LK AS P+I+STG + + Y+ I ++ C++ S YP P
Sbjct: 132 ASGDLVNTPLLKKVASYGKPIIVSTGGGTLADARLAYETIMPINRNLCIMQCTSGYPPPH 191
Query: 831 EDCNLTVLQDYK 866
E+ NL V++ ++
Sbjct: 192 EELNLRVIETFR 203
>UniRef50_Q9RDX5 Cluster: N-acetylneuraminic acid condensing enzyme;
n=6; Bacteria|Rep: N-acetylneuraminic acid condensing
enzyme - Legionella pneumophila
Length = 338
Score = 136 bits (328), Expect = 2e-30
Identities = 79/190 (41%), Positives = 112/190 (58%), Gaps = 7/190 (3%)
Frame = +3
Query: 309 CFIIAEVGQNHQGDIGIAKQLIKAAKDAGASCVKFQKTCLKEKFTKKYLERS-YDNHNS- 482
CFIIAE G NH GD+ +AK+L+ AAK++GA VKFQ T + K +E++ Y +N+
Sbjct: 3 CFIIAEAGVNHNGDLQLAKELVYAAKESGADAVKFQ-TFKADTLVNKTVEKAEYQKNNAP 61
Query: 483 WGKTYGDHKKHLEFSESQYRELFKYAHEIGILFTASAMDMVSFDFLVNLKVPFIKIGSGD 662
T + K LE SE + L + A+ +GI F ++ D S DFL++L V +KI SG+
Sbjct: 62 ESSTQYEMLKALELSEEDHYLLSELANSLGIEFMSTGFDEQSIDFLISLGVKRLKIPSGE 121
Query: 663 SNNLLFLKYAASKKLPLIISTGMVDKSAVKTIYDII-----SSEHKQFCLLHXISAYPVP 827
N+ +L++ ASKKLPLIISTGM D V+ D + +S LLH S YP
Sbjct: 122 ITNVPYLQHCASKKLPLIISTGMCDLQEVRVAIDTVKPYYGNSLSDYLVLLHCTSNYPAS 181
Query: 828 FEDCNLTVLQ 857
++D NL +Q
Sbjct: 182 YQDVNLKAMQ 191
>UniRef50_A6D0F9 Cluster: Sialic acid synthase; n=2;
Gammaproteobacteria|Rep: Sialic acid synthase - Vibrio
shilonii AK1
Length = 751
Score = 135 bits (326), Expect = 3e-30
Identities = 74/196 (37%), Positives = 105/196 (53%), Gaps = 1/196 (0%)
Frame = +3
Query: 288 KVGGNNPCFIIAEVGQNHQGDIGIAKQLIKAAKDAGASCVKFQKTCLKEKFTKKYLERSY 467
K+G P FIIAE+G NH G + +AK+L+ AK AGA CVKFQ + + + +
Sbjct: 123 KIGDQEPSFIIAEIGNNHNGSLELAKELVDLAKAAGADCVKFQMRDMASMYNNEGDDD-- 180
Query: 468 DNHNSWGKTYG-DHKKHLEFSESQYRELFKYAHEIGILFTASAMDMVSFDFLVNLKVPFI 644
D G Y D K + + ++ E+F+Y + IL + D S D L + V
Sbjct: 181 DASQDLGAQYVLDLLKRFQLCDEEFVEIFEYCKQKEILALCTPFDEASADKLEKIGVAGF 240
Query: 645 KIGSGDSNNLLFLKYAASKKLPLIISTGMVDKSAVKTIYDIISSEHKQFCLLHXISAYPV 824
K+ S D N LKY A+KK+PLI+STGM + + + +++ E F LLH S YP
Sbjct: 241 KVASADLTNHRLLKYLAAKKVPLILSTGMSVEQEIISAVELLEKESASFALLHCNSTYPA 300
Query: 825 PFEDCNLTVLQDYKIL 872
PF+D NLT L+ K L
Sbjct: 301 PFKDVNLTYLKRLKSL 316
>UniRef50_A6L7H8 Cluster: Sialic acid synthase; n=1; Bacteroides
vulgatus ATCC 8482|Rep: Sialic acid synthase -
Bacteroides vulgatus (strain ATCC 8482 / DSM 1447 / NCTC
11154)
Length = 334
Score = 128 bits (310), Expect = 3e-28
Identities = 76/192 (39%), Positives = 104/192 (54%), Gaps = 4/192 (2%)
Frame = +3
Query: 303 NPCFIIAEVGQNHQGDIGIAKQLIKAAKDAGASCVKFQKTCLKEKFTKKYLERS-YDNHN 479
N +IIAE G NH G + +A QL AAKDAGA VKFQ T EK + E + Y +N
Sbjct: 3 NHVYIIAEAGVNHNGRLDLALQLCNAAKDAGADAVKFQ-TWKTEKIVTRNAELAVYQENN 61
Query: 480 SWGKTYGDHK--KHLEFSESQYRELFKYAHEIGILFTASAMDMVSFDFLVNLKVPFIKIG 653
KT K K LE S + + + EIGI F ++ ++ S DFL N +PFIK+G
Sbjct: 62 ISDKTKSQFKMLKELELSYDNFEVVKNHCDEIGIQFLSTPDEIDSLDFLCNFNLPFIKLG 121
Query: 654 SGDSNNLLFLKYAASKKLPLIISTGMVDKSAVKTIY-DIISSEHKQFCLLHXISAYPVPF 830
SGD N+ FL+ S+ + +++STGM V+ Y +I + K LLH + YP P
Sbjct: 122 SGDVTNIPFLRLVGSRHIDVVLSTGMSYLGDVEIAYRTLIEAGAKSVSLLHCTTNYPCPM 181
Query: 831 EDCNLTVLQDYK 866
+ NL +Q K
Sbjct: 182 HEVNLRAIQTLK 193
>UniRef50_A0NMM3 Cluster: N-acylneuraminate-9-phosphate synthase;
n=1; Stappia aggregata IAM 12614|Rep:
N-acylneuraminate-9-phosphate synthase - Stappia
aggregata IAM 12614
Length = 287
Score = 128 bits (309), Expect = 4e-28
Identities = 70/186 (37%), Positives = 105/186 (56%), Gaps = 1/186 (0%)
Frame = +3
Query: 312 FIIAEVGQNHQGDIGIAKQLIKAAKDAGASCVKFQKTCLKEKFTKKYLERSYDNHNSWGK 491
++IAE+G NH GDI A ++I+ +K+AG VKFQK + ++ + L R +N +G
Sbjct: 8 YVIAEIGINHNGDIDQALEMIRKSKEAGCDAVKFQKRTVDVVYSAEELARPREN--VFGT 65
Query: 492 TYGDHKKHLEFSESQYRELFKYAHEIGILFTASAMDMVSFDFLVNLKVPFIKIGSGDSNN 671
T GD K+ LEF ++ Y + K E+GI + AS D S DFL++ P+IK+ S +
Sbjct: 66 TNGDLKRGLEFGKADYDRIDKLCKELGIDWFASPWDEGSVDFLLDYDTPYIKVASAMVTD 125
Query: 672 LLFLKYAASKKLPLIISTGMVDKSAVKTIYDIISSEHKQF-CLLHXISAYPVPFEDCNLT 848
FL+Y A PL++STGM D + VK+ D+I + CL H S YP ++ NL
Sbjct: 126 RDFLEYCARSGRPLLVSTGMSDMAMVKSFVDVIERSGGEIACLYHCTSTYPTRDDEINLR 185
Query: 849 VLQDYK 866
+ K
Sbjct: 186 GISTLK 191
>UniRef50_Q74B32 Cluster: Polysaccharide biosynthesis protein,
putative; n=1; Geobacter sulfurreducens|Rep:
Polysaccharide biosynthesis protein, putative -
Geobacter sulfurreducens
Length = 350
Score = 128 bits (308), Expect = 5e-28
Identities = 70/191 (36%), Positives = 104/191 (54%), Gaps = 3/191 (1%)
Frame = +3
Query: 282 DVKVGGNNPCFIIAEVGQNHQGDIGIAKQLIKAAKDAGASCVKFQKTCLKEKFTKKYLER 461
+V VG NP ++IAE+G NH GD+ + +QLI AA +AGA VKFQ ++ ER
Sbjct: 8 NVPVGAENPPYVIAEIGSNHNGDMNLCRQLIDAAAEAGAHAVKFQSWTENSLIAREEYER 67
Query: 462 S--YDNHNSWGKTYGDHKKHLEFSESQYRELFKYAHEIGILFTASAMDMVSFDFLVNLKV 635
+ Y + + D K + + Q+RE Y E GI F ++ D L +L V
Sbjct: 68 NTEYSDKKRHFGSLRDMVKTYQLTTDQHREAHAYCRERGIAFCSTPFSPEEADLLESLDV 127
Query: 636 PFIKIGSGDSNNLLFLKYAASKKLPLIISTGMVDKSAVKTIYDIISSE-HKQFCLLHXIS 812
PF KI S D +L FLKY A K+ P+++STGM + ++ + + +E + Q LLH +S
Sbjct: 128 PFFKIASMDIVHLPFLKYVARKRRPMLLSTGMATLAEIEAAVETVRAEGNDQVVLLHCVS 187
Query: 813 AYPVPFEDCNL 845
YP +E +L
Sbjct: 188 IYPPDYEMIHL 198
>UniRef50_Q04TT0 Cluster: N-acetyl neuraminic (Sialic) acid
synthetase; n=4; Leptospira|Rep: N-acetyl neuraminic
(Sialic) acid synthetase - Leptospira borgpetersenii
serovar Hardjo-bovis (strain JB197)
Length = 332
Score = 126 bits (305), Expect = 1e-27
Identities = 78/210 (37%), Positives = 110/210 (52%), Gaps = 1/210 (0%)
Frame = +3
Query: 273 ITEDVKVGGNNPCFIIAEVGQNHQGDIGIAKQLIKAAKDAGASCVKFQKTCLKEKFTKKY 452
I ++ VG +P ++AE+G NH D I K+ I AAK AGA VKFQ + + E+F
Sbjct: 9 IASELYVGSESPPIVVAEIGLNHNNDEEIGKKTIAAAKKAGAQVVKFQ-SYVTEEFI--- 64
Query: 453 LERSYDNHNSWGKTYGDHKKHLEFSESQYRELFKYAHEIGILFTASAMDMVSFDFLVNLK 632
D HN K D K E SE+ +R+ K A + G+ F ++ + + S L++LK
Sbjct: 65 -----DVHNPDAKILVDIFKKYELSETMHRKFQKTAEDEGLFFFSTPLCVNSLHLLLSLK 119
Query: 633 VPFIKIGSGDSNNLLFLKYAASKKLPLIISTGMVDKSAVKTIYDIISSE-HKQFCLLHXI 809
VP IKI SGD N L A KLP+I+S+G D V + E + CLLH +
Sbjct: 120 VPAIKIASGDITNKTLLLETAKSKLPVILSSGAADFFEVNRAISFLEKEGTDKLCLLHCV 179
Query: 810 SAYPVPFEDCNLTVLQDYKILLMYLLXIRD 899
S YP P E NL V++ +K L + + D
Sbjct: 180 SLYPTPPEKANLKVVETFKNLYPFPVGFSD 209
>UniRef50_Q58465 Cluster: Uncharacterized protein MJ1065; n=1;
Methanocaldococcus jannaschii|Rep: Uncharacterized
protein MJ1065 - Methanococcus jannaschii
Length = 337
Score = 126 bits (303), Expect = 2e-27
Identities = 77/204 (37%), Positives = 108/204 (52%), Gaps = 1/204 (0%)
Frame = +3
Query: 258 MLEVKITEDVKVGGNNPCFIIAEVGQNHQGDIGIAKQLIKAAKDAGASCVKFQKTCLKEK 437
M ++KI D VG P FIIAE G NH GDI I K+L+K AK GA +KFQ ++
Sbjct: 1 MEKIKIG-DRYVGKGEPTFIIAEGGLNHNGDIDIGKELVKEAKKCGADAIKFQSYHTEDF 59
Query: 438 FTKKYLERSYDNHNSWGKTYGDHKKHLEFSESQYRELFKYAHEIGILFTASAMDMVSFDF 617
+KK Y + K LE SE ++ EL +YA +IGI+F ++ +D+ D
Sbjct: 60 ISKK-------------SEYYELFKSLELSEEEFYELKEYAEKIGIMFISTPLDLKYVDI 106
Query: 618 LVNLKVPFIKIGSGDSNNLLFLKYAASKKLPLIISTGMVDKSAVKTIYDIISSEH-KQFC 794
L + VP KI SGD L+ A P+I+STGM D + ++ + +
Sbjct: 107 LNKMNVPAFKIASGDLTFYPLLEKVAKTGKPVILSTGMSDIGEIWEAVKVLENNGCRDII 166
Query: 795 LLHXISAYPVPFEDCNLTVLQDYK 866
LLH IS+YP P+ED NL ++ K
Sbjct: 167 LLHCISSYPTPYEDVNLNAIKTLK 190
>UniRef50_Q1IMQ8 Cluster: N-acetylneuraminate synthase; n=16;
Bacteria|Rep: N-acetylneuraminate synthase -
Acidobacteria bacterium (strain Ellin345)
Length = 300
Score = 124 bits (299), Expect = 6e-27
Identities = 66/188 (35%), Positives = 102/188 (54%)
Frame = +3
Query: 291 VGGNNPCFIIAEVGQNHQGDIGIAKQLIKAAKDAGASCVKFQKTCLKEKFTKKYLERSYD 470
VG + PC++IAE+G NH GD+ IAK+LI A AG VKFQK + +T L + +
Sbjct: 20 VGKDQPCYVIAEIGINHNGDMDIAKRLISVAVGAGCDAVKFQKRTIDVVYTAAELAKPRE 79
Query: 471 NHNSWGKTYGDHKKHLEFSESQYRELFKYAHEIGILFTASAMDMVSFDFLVNLKVPFIKI 650
N +G T GD K+ LEF +++E+ +Y E+ + + ASA D S DF+ VP KI
Sbjct: 80 N--PFGATNGDLKRGLEFGLEEFKEIDRYCREVRMPWFASAWDEASVDFIAQFDVPCFKI 137
Query: 651 GSGDSNNLLFLKYAASKKLPLIISTGMVDKSAVKTIYDIISSEHKQFCLLHXISAYPVPF 830
S + L++ + P+++STGM + D++ ++ LL S YP +
Sbjct: 138 ASASLTDDNLLRHTRATGKPVMLSTGMSTVEQIDHAVDVLGKDN--LILLQACSTYPAYY 195
Query: 831 EDCNLTVL 854
E+ NL +
Sbjct: 196 EELNLKAI 203
>UniRef50_A4FX91 Cluster: N-acylneuraminate-9-phosphate synthase;
n=5; cellular organisms|Rep:
N-acylneuraminate-9-phosphate synthase - Methanococcus
maripaludis
Length = 348
Score = 123 bits (297), Expect = 1e-26
Identities = 72/189 (38%), Positives = 104/189 (55%), Gaps = 3/189 (1%)
Frame = +3
Query: 297 GNNPCFIIAEVGQNHQGDIGIAKQLIKAAKDAGASCVKFQKTCLKEKFTKKYLERSYDNH 476
G FIIAE G NH G + +AK+LI A +AG VKFQ + T+ + Y
Sbjct: 11 GLKNAFIIAEAGVNHNGSLELAKKLIDVAFEAGVDAVKFQTFKTENVVTENAEKAEYQIQ 70
Query: 477 NSWGKTYGDHK--KHLEFSESQYRELFKYAHEIGILFTASAMDMVSFDFLVNLKVPFIKI 650
N+ ++ ++ K LE SE + L+ Y E GILF ++ D S DFL +L VP KI
Sbjct: 71 NTGVESESQYEMIKKLELSEKDFERLYNYCQEKGILFLSTPFDFESADFLDDL-VPLFKI 129
Query: 651 GSGDSNNLLFLKYAASKKLPLIISTGMVDKSAV-KTIYDIISSEHKQFCLLHXISAYPVP 827
S D NN+ FLK+ A KK P+IISTGM + + + + ++ + + LLH +++YP
Sbjct: 130 SSTDLNNIPFLKHIAKKKKPVIISTGMGTLCEIEEAVTALKNAGNHEIMLLHCVTSYPAK 189
Query: 828 FEDCNLTVL 854
E NL V+
Sbjct: 190 DESLNLNVI 198
>UniRef50_Q0M1E8 Cluster: N-acylneuraminate-9-phosphate synthase;
n=2; Bacteria|Rep: N-acylneuraminate-9-phosphate
synthase - Caulobacter sp. K31
Length = 310
Score = 121 bits (291), Expect = 6e-26
Identities = 65/181 (35%), Positives = 99/181 (54%)
Frame = +3
Query: 312 FIIAEVGQNHQGDIGIAKQLIKAAKDAGASCVKFQKTCLKEKFTKKYLERSYDNHNSWGK 491
F+IAE+G NH GD+ I KQLI+AA+DAG VKFQK + +T + L + + WG
Sbjct: 34 FVIAEIGINHNGDLEITKQLIRAARDAGCDAVKFQKRTIDIVYTPEVLAQP--RQSPWGD 91
Query: 492 TYGDHKKHLEFSESQYRELFKYAHEIGILFTASAMDMVSFDFLVNLKVPFIKIGSGDSNN 671
T K+ LEF +++Y + Y E+G+ + ASA D+ S FL +P+ KI S +
Sbjct: 92 TQRAQKEGLEFGKAEYDVIDAYCRELGLAWFASAWDVPSQTFLAAYDLPYNKIASAMLTH 151
Query: 672 LLFLKYAASKKLPLIISTGMVDKSAVKTIYDIISSEHKQFCLLHXISAYPVPFEDCNLTV 851
++ A++ + STGM + T +I+ + F L+H +S YP P D NL
Sbjct: 152 RPLIEAVAAEGKLVFASTGMCTFEQIDTAVEILRAAACPFVLMHTVSTYPTPPADLNLLT 211
Query: 852 L 854
+
Sbjct: 212 I 212
>UniRef50_A7DQW3 Cluster: N-acylneuraminate-9-phosphate synthase;
n=1; Candidatus Nitrosopumilus maritimus SCM1|Rep:
N-acylneuraminate-9-phosphate synthase - Candidatus
Nitrosopumilus maritimus SCM1
Length = 349
Score = 120 bits (288), Expect = 1e-25
Identities = 71/211 (33%), Positives = 111/211 (52%), Gaps = 5/211 (2%)
Frame = +3
Query: 264 EVKITEDVKVGGNNPCFIIAEVGQNHQGDIGIAKQLIKAAKDAGASCVKFQKTCLKEKFT 443
++ I +D ++ P +IIAE+G NH G+I AK+LI A DAGA+ VKFQK L + +
Sbjct: 7 DIVIGKD-RISTKEPAYIIAEIGINHNGNITTAKKLIDVAVDAGANAVKFQKRSLNDIYR 65
Query: 444 KKYLERSYDNHNSWG-KTYGDHKKHLEFSESQYRELFKYAHEIGILFTASAMDMVSFDFL 620
+ L+ N S G + D +EF + Y+EL +Y E I F + D+ S +FL
Sbjct: 66 EDVLKDP--NIESQGLEILLDVLNEVEFDDDAYKELTEYCKEKHITFLCTPWDIPSVEFL 123
Query: 621 VNLKVPFIKIGSGDSNNLLFLKYAASKKLPLIISTGMVDKSAVKTIYDIISSEHKQFCLL 800
+P KI S D N + PLI+STGM + + ++ + ++ +F LL
Sbjct: 124 EKFDLPAYKIASADMTNFPLISSLIQTGKPLIVSTGMSNMNEIEKTVSFMKEKNAKFALL 183
Query: 801 HXISAYPVPFEDCNLTVL----QDYKILLMY 881
H S YP P E NL ++ + +++L+ Y
Sbjct: 184 HCNSTYPAPVETLNLELISLLKEKFQVLIGY 214
>UniRef50_Q0IDR1 Cluster: N-acetylneuraminic acid condensing enzyme;
n=1; Synechococcus sp. CC9311|Rep: N-acetylneuraminic
acid condensing enzyme - Synechococcus sp. (strain
CC9311)
Length = 347
Score = 112 bits (270), Expect = 2e-23
Identities = 66/191 (34%), Positives = 97/191 (50%), Gaps = 2/191 (1%)
Frame = +3
Query: 288 KVGGNNPCFIIAEVGQNHQGDIGIAKQLIKAAKDAGASCVKFQKTCLKEKFTKKYLERSY 467
++ +P +I+AE+G NH G+I +A +LI +AKDAGA VKFQ E + Y
Sbjct: 11 RISSIDPTYIVAEIGVNHNGNISLAHKLIDSAKDAGADAVKFQTYVTDELVIRNTRTAKY 70
Query: 468 DNHNSWGKTYGDHKKHLEFSESQYRELFKYAHEIGILFTASAMDMVSFDFLVNLKVPFIK 647
N+ + E S + EL+++ GI F ++ D VS F+ NLK IK
Sbjct: 71 QKENALFDDQYTMLEKYELSFESFHELYRHCAAAGIDFLSTPFDPVSLRFIANLKPVAIK 130
Query: 648 IGSGDSNNLLFLKYAASKKLPLIISTGMVDKSAVKTIYDIIS--SEHKQFCLLHXISAYP 821
SG+ N + L AA +LP+I+STGM S + + D I+ + +L +S YP
Sbjct: 131 WASGELTNKMLLDQAAKTRLPIILSTGM---SRINDVDDAITWIGRNTPLVVLQCVSNYP 187
Query: 822 VPFEDCNLTVL 854
D NL VL
Sbjct: 188 AAMSDQNLRVL 198
>UniRef50_UPI00015B984F Cluster: UPI00015B984F related cluster; n=1;
unknown|Rep: UPI00015B984F UniRef100 entry - unknown
Length = 361
Score = 110 bits (265), Expect = 8e-23
Identities = 62/190 (32%), Positives = 99/190 (52%), Gaps = 2/190 (1%)
Frame = +3
Query: 291 VGGNNPCFIIAEVGQNHQGDIGIAKQLIKAAKDAGASCVKFQKTCLKEKFTKKYLERSYD 470
+G + CF+IAE G NH GD+ +A +LI A AGA +KFQ + + + +Y
Sbjct: 23 IGNDGRCFVIAEAGVNHNGDVAMAHRLIDVAAAAGADAIKFQTFNAETLVDRSARKAAYQ 82
Query: 471 NHNSWGKTYG-DHKKHLEFSESQYRELFKYAHEIGILFTASAMDMVSFDFLVNLKVPFIK 647
N+ ++ + + LE YR L +A + GI ++ D S DFL L VP K
Sbjct: 83 VTNTGSESSQFEMLRSLELPAQAYRALQDHAGQAGIALISTPFDEASVDFLATLGVPAYK 142
Query: 648 IGSGDSNNLLFLKYAASKKLPLIISTGMVDKSAVK-TIYDIISSEHKQFCLLHXISAYPV 824
+ SGD N L+ A+K P+IISTGM + + ++ + + ++ ++ C L S+YP
Sbjct: 143 VSSGDLTNHFLLEAVAAKGKPVIISTGMANLADIEGALACLRTAGAREVCALQCTSSYPA 202
Query: 825 PFEDCNLTVL 854
P + NL +
Sbjct: 203 PPDQINLRTI 212
>UniRef50_Q04TM5 Cluster: N-acetylneuraminic acid (Sialic acid)
synthetase; n=2; Leptospira borgpetersenii serovar
Hardjo-bovis|Rep: N-acetylneuraminic acid (Sialic acid)
synthetase - Leptospira borgpetersenii serovar
Hardjo-bovis (strain JB197)
Length = 282
Score = 110 bits (264), Expect = 1e-22
Identities = 66/195 (33%), Positives = 103/195 (52%)
Frame = +3
Query: 282 DVKVGGNNPCFIIAEVGQNHQGDIGIAKQLIKAAKDAGASCVKFQKTCLKEKFTKKYLER 461
++K+GGNNP FIIAE G NH GD+ +A ++I A DA A+ +KFQ +E+F +
Sbjct: 9 NIKIGGNNPVFIIAEAGLNHGGDLNLALRMIDEAADAKANAIKFQAYNSEERFGE----- 63
Query: 462 SYDNHNSWGKTYGDHKKHLEFSESQYRELFKYAHEIGILFTASAMDMVSFDFLVNLKVPF 641
K + K EF + ++ L + + + ILF A+ D+ + + L + V
Sbjct: 64 --------NKEAVNLVKPAEFGKKEFLLLKERSQKKNILFFATPFDVPNLNMLKEIGVEI 115
Query: 642 IKIGSGDSNNLLFLKYAASKKLPLIISTGMVDKSAVKTIYDIISSEHKQFCLLHXISAYP 821
+KI S D N+ L+ AA L +I+S G S ++T I + F LLH +S+YP
Sbjct: 116 LKIASCDICNITLLEAAADSGLIVILSRGTASASEIETAVSIFKKKKSPFILLHCVSSYP 175
Query: 822 VPFEDCNLTVLQDYK 866
+ D NL+ +Q K
Sbjct: 176 MNEIDANLSAIQTLK 190
>UniRef50_Q893U6 Cluster: N-acetylneuraminate synthase; n=1;
Clostridium tetani|Rep: N-acetylneuraminate synthase -
Clostridium tetani
Length = 351
Score = 109 bits (261), Expect = 2e-22
Identities = 61/201 (30%), Positives = 104/201 (51%), Gaps = 8/201 (3%)
Frame = +3
Query: 288 KVGGNNPCFIIAEVGQNHQGDIGIAKQLIKAAKDAGASCVKFQKTCLKEKFTKKYLERSY 467
K+G N P +I+AE+G NH GD+ +AK++I+ A + G VKFQ +T K L
Sbjct: 11 KIGENYPAYIVAEIGANHNGDVNLAKRMIEVAAECGVDAVKFQ------TYTAKELVSDT 64
Query: 468 DNHNSWG-------KTYGDHKKHLEFSESQYRELFKYAHEIGILFTASAMDMVSFDFLVN 626
D +WG +T G + ++E+F+YA+++G++ ++ + +FL
Sbjct: 65 DRILTWGPCGKQKTETIGKMFDRIALPREAHKEVFEYANKLGLMAFSTPFSIKGVEFLNE 124
Query: 627 LKVPFIKIGSGDSNNLLFLKYAASKKLPLIISTGMVD-KSAVKTIYDIISSEHKQFCLLH 803
L+VP K+ + D + L LK K P+++S G A I +I S ++ ++H
Sbjct: 125 LEVPCFKVAASDVDYLDILKEIGKTKKPVMLSLGKCTLGEADLAIETLIESGCEKIVIMH 184
Query: 804 XISAYPVPFEDCNLTVLQDYK 866
+S YP P + NL V++ K
Sbjct: 185 CVSQYPSPINEMNLKVIEGLK 205
>UniRef50_A5MZ25 Cluster: Predicted polysaccharide biosynthesis
protein; n=1; Clostridium kluyveri DSM 555|Rep:
Predicted polysaccharide biosynthesis protein -
Clostridium kluyveri DSM 555
Length = 335
Score = 109 bits (261), Expect = 2e-22
Identities = 68/204 (33%), Positives = 105/204 (51%), Gaps = 1/204 (0%)
Frame = +3
Query: 258 MLEVKITEDVKVGGNNPCFIIAEVGQNHQGDIGIAKQLIKAAKDAGASCVKFQKTCLKEK 437
M ++KI + +G +PCFIIAE G NH GDI AK+L+ A +AGA+ VKFQ +
Sbjct: 1 MNDIKIGNKI-IGNTHPCFIIAEAGSNHNGDIKQAKELVDIAVEAGANAVKFQTFTADKL 59
Query: 438 FTKKYLERSYDNHNSWGKTYGDHKKHLEFSESQYRELFKYAHEIGILFTASAMDMVSFDF 617
F+K NH + K+ EF ++E+ +Y + GI+F + + D
Sbjct: 60 FSK--------NHPA-----NKIVKNFEFKLEWHKEMKEYCDKKGIMFITTPFQKDAVDL 106
Query: 618 LVNLKVPFIKIGSGDSNNLLFLKYAASKKLPLIISTGMVDKSAVKTIYD-IISSEHKQFC 794
L L + KI SGD + L Y ++ P+I+++GM VK ++ I + + +
Sbjct: 107 LEKLNIEGYKIASGDMDYYPLLDYISNTGKPIILASGMAYMDEVKEAFNRIKNGKTEDIA 166
Query: 795 LLHXISAYPVPFEDCNLTVLQDYK 866
+LH +S YP ED NL +Q K
Sbjct: 167 ILHCVSNYPPKDEDINLKAIQTIK 190
>UniRef50_Q3AZQ1 Cluster: N-acylneuraminate-9-phosphate synthase;
n=17; Bacteria|Rep: N-acylneuraminate-9-phosphate
synthase - Synechococcus sp. (strain CC9902)
Length = 762
Score = 108 bits (259), Expect = 4e-22
Identities = 65/191 (34%), Positives = 97/191 (50%), Gaps = 2/191 (1%)
Frame = +3
Query: 291 VGGNNPCFIIAEVGQNHQGDIGIAKQLIKAAKDAGASCVKFQKTCLKEKFTKKYLERSYD 470
+G +PCF+IAE+G NH GDI A QLI AA AGA C KFQ + + ++ +S D
Sbjct: 128 IGAEHPCFVIAEIGNNHNGDINTALQLIDAAHAAGADCAKFQMRDMGQLYSNS--GKSSD 185
Query: 471 NHNSWGKTYG-DHKKHLEFSESQYRELFKYAHEIGILFTASAMDMVSFDFLVNLKVPFIK 647
+ G Y D + + S+ + F Y+ G++ + D S L + K
Sbjct: 186 MASDLGTQYTLDLLERFQLSDDELFHCFDYSASKGLVPLCTPWDQTSLQKLNQWGMEGFK 245
Query: 648 IGSGD-SNNLLFLKYAASKKLPLIISTGMVDKSAVKTIYDIISSEHKQFCLLHXISAYPV 824
+ S D +N+ L + AA+ K PLI STGM + +++ + + LLH S YP
Sbjct: 246 VASADFTNHALITQLAATGK-PLICSTGMASELEIRSGIRHLQKAGANYVLLHCNSTYPT 304
Query: 825 PFEDCNLTVLQ 857
PF+D NL L+
Sbjct: 305 PFKDVNLRYLE 315
>UniRef50_Q8A711 Cluster: Sialic acid synthase; n=1; Bacteroides
thetaiotaomicron|Rep: Sialic acid synthase - Bacteroides
thetaiotaomicron
Length = 346
Score = 107 bits (257), Expect = 8e-22
Identities = 59/192 (30%), Positives = 95/192 (49%), Gaps = 11/192 (5%)
Frame = +3
Query: 312 FIIAEVGQNHQGDIGIAKQLIKAA-----KDAGA------SCVKFQKTCLKEKFTKKYLE 458
+II E+GQNH G + +AK +I+ +D + VK K L E+ +
Sbjct: 5 YIIGEIGQNHNGSVDLAKLIIELISRPVHEDVFGMDFMPMNAVKMTKRDLSEELAVSQMN 64
Query: 459 RSYDNHNSWGKTYGDHKKHLEFSESQYRELFKYAHEIGILFTASAMDMVSFDFLVNLKVP 638
+ YDN NS+G+TYG+H+ LE + + E++KYA +G+ F + L
Sbjct: 65 QIYDNPNSFGRTYGEHRAFLELDDQAHFEIYKYAKSLGLDFIETLCAKGCLSLLKLFTPD 124
Query: 639 FIKIGSGDSNNLLFLKYAASKKLPLIISTGMVDKSAVKTIYDIISSEHKQFCLLHXISAY 818
+K+ S D NL L+ A +P+I+STGM + + D+I+ H +LH +S Y
Sbjct: 125 RLKVASRDLTNLPLLEALAETHIPIILSTGMAGQRELDNALDVITRYHSNIAILHCVSQY 184
Query: 819 PVPFEDCNLTVL 854
P + NL +
Sbjct: 185 PTHPNNLNLRTI 196
>UniRef50_Q0FYM0 Cluster: N-acylneuraminate-9-phosphate synthase;
n=1; Fulvimarina pelagi HTCC2506|Rep:
N-acylneuraminate-9-phosphate synthase - Fulvimarina
pelagi HTCC2506
Length = 347
Score = 105 bits (252), Expect = 3e-21
Identities = 65/186 (34%), Positives = 94/186 (50%), Gaps = 2/186 (1%)
Frame = +3
Query: 303 NPCFIIAEVGQNHQGDIGIAKQLIKAAKDAGASCVKFQKTCLKEKFTKKYLERSYDNHNS 482
N F++AE G NH G I A +++AA AGA +KFQ T + +Y N
Sbjct: 13 NWVFVVAEAGVNHNGSIERALDMVEAAARAGADAIKFQTFRAAGLVTANAEKAAYQKRND 72
Query: 483 WGKT-YGDHKKHLEFSESQYRELFKYAHEIGILFTASAMDMVSFDFLVNLKVPFIKIGSG 659
T + LE SESQ+R + + +GI F ++ D S DFL +L V KI SG
Sbjct: 73 GIDTNQAEMLSALELSESQWRTIKDHCSMVGISFLSTPFDEDSADFLESLGVEAFKISSG 132
Query: 660 DSNNLLFLKYAASKKLPLIISTGMVDKSAVKTIYDII-SSEHKQFCLLHXISAYPVPFED 836
D +L FL++ A K P+IISTGM + + ++ D I ++ +LH +S YP
Sbjct: 133 DLTHLAFLQHVARKGRPMIISTGMANLADIEEAVDAIEAAGSPPLAILHCVSDYPADPAS 192
Query: 837 CNLTVL 854
NL +
Sbjct: 193 SNLMAI 198
>UniRef50_Q2Y4J1 Cluster: NeuB family member; n=5; cellular
organisms|Rep: NeuB family member - uncultured archaeon
Length = 360
Score = 105 bits (252), Expect = 3e-21
Identities = 76/222 (34%), Positives = 114/222 (51%), Gaps = 11/222 (4%)
Frame = +3
Query: 267 VKITEDVKVGGNNPCFIIAEVGQNH-----QGDIG---IAKQLIKAAKDAGASCVKFQKT 422
+KI E+ ++ FI+AE G N+ +G+I AK +I+ A D+GA +KFQ T
Sbjct: 5 IKI-ENREISPTKKPFIVAEAGVNYYDIAKKGNIEPLEAAKLMIEKAADSGADAIKFQ-T 62
Query: 423 CLKEKFTKKYLERSYDNHNSWGKT-YGDHKKHLEFSESQYRELFKYAHEIGILFTASAMD 599
E+ KY +D K+ Y KK +F E +Y+EL YA ILF ++ D
Sbjct: 63 YKAERIASKYSPAYWDVTKENTKSQYELFKKFDKFGEDEYKELAGYAANTDILFMSTPFD 122
Query: 600 MVSFDFLVNLKVPFIKIGSGDSNNLLFLKYAASKKLPLIISTGMVDKSAVKTIYDIISSE 779
+ DFL L +P KI S D N+ F+ Y A K+ P+ +STG +K + I SE
Sbjct: 123 NEAVDFLDKL-MPVFKISSSDITNIPFISYVARKRKPIFLSTGASTIEEIKEAVNAIESE 181
Query: 780 -HKQFCLLHXISAYPVPFEDCNLTVLQD-YKILLMYLLXIRD 899
+ + +LH I YP +ED NL +++ K+ YL+ D
Sbjct: 182 GNDKIVILHCILNYPTKYEDANLGMIKHIQKVFPGYLVGYSD 223
>UniRef50_A4AP54 Cluster: N-acetylneuraminate synthase; n=3;
cellular organisms|Rep: N-acetylneuraminate synthase -
Flavobacteriales bacterium HTCC2170
Length = 351
Score = 104 bits (250), Expect = 5e-21
Identities = 64/201 (31%), Positives = 101/201 (50%), Gaps = 2/201 (0%)
Frame = +3
Query: 258 MLEVKITEDVKVGGNNPCFIIAEVGQNHQGDIGIAKQLIKAAKDAGASCVKFQKTCLKEK 437
M +KI ED + +PCFIIAE G NH G + +A +L++ AK+ G CVKFQ +
Sbjct: 1 MKSIKI-EDFLISKESPCFIIAEAGVNHNGKLEMALELVRKAKEIGVDCVKFQTFTAESV 59
Query: 438 FTKKYLERSYD-NHNSWGKTYGDHKKHLEFSESQYRELFKYAHEIGILFTASAMDMVSFD 614
TKK + +Y ++ + K LE S Y ++ + ++ I F ++ + D
Sbjct: 60 ITKKAPKANYQLEVTDPAESQFEMLKKLELSGDDYIKIIEECNKQNITFLSTPYNEEDAD 119
Query: 615 FLVNLKVPFIKIGSGDSNNLLFLKYAASKKLPLIISTGMVDKSAV-KTIYDIISSEHKQF 791
FL L V KI SG L FL++ A P+I+S+GM + V + + I + + Q
Sbjct: 120 FLNKLGVSAFKIASGQIVELAFLEHVAKFGKPIILSSGMATLAEVYEAVMTIREAGNNQM 179
Query: 792 CLLHXISAYPVPFEDCNLTVL 854
+L + YP ED N+ +
Sbjct: 180 AILQCTTNYPSQNEDANIRAM 200
>UniRef50_Q8DDZ7 Cluster: Sialic acid synthase; n=5; Bacteria|Rep:
Sialic acid synthase - Vibrio vulnificus
Length = 333
Score = 103 bits (248), Expect = 9e-21
Identities = 77/191 (40%), Positives = 97/191 (50%), Gaps = 6/191 (3%)
Frame = +3
Query: 303 NPCFIIAEVGQNHQGDIGIAKQLIKAAKDAGASCVKFQ--KTCLKEKFTKKYLERSYDNH 476
N FIIAE G NH GDI +AKQLI AA DAG VKFQ KT L K E +N
Sbjct: 3 NKTFIIAEAGVNHNGDIRLAKQLIDAAADAGVDAVKFQTWKTELLVTEDAKMAEYQVEN- 61
Query: 477 NSWGKTYGDHKKHLEFSESQYRELFKYAHEIGILFTASAMDMVSFDFLVNLKVPFIKIGS 656
+T + K LE S + EL Y + GI F ++ + S FL L+ F KIGS
Sbjct: 62 TQREETQFEMLKRLELSYDDFTELKSYCDDKGITFMSTPDEEQSATFLDGLQAVF-KIGS 120
Query: 657 GDSNNLLFLKYAASKKLPLIISTGMVDKS----AVKTIYDIISSEHKQFCLLHXISAYPV 824
G+ N FL++ AS P+I+STGM S AV T+ D +LH + YP
Sbjct: 121 GELTNTPFLRHIASFAKPVILSTGMGYLSEVEHAVVTLRD-AGLSLDMITVLHATTDYPT 179
Query: 825 PFEDCNLTVLQ 857
ED NL ++
Sbjct: 180 APEDVNLLAMK 190
>UniRef50_A7GGU3 Cluster: NeuB family protein; n=1; Clostridium
botulinum F str. Langeland|Rep: NeuB family protein -
Clostridium botulinum (strain Langeland / NCTC 10281 /
Type F)
Length = 343
Score = 102 bits (245), Expect = 2e-20
Identities = 66/195 (33%), Positives = 102/195 (52%), Gaps = 1/195 (0%)
Frame = +3
Query: 288 KVGGNNPCFIIAEVGQNHQGDIGIAKQLIKAAKDAGASCVKFQKTCLKEKFTKKYLERSY 467
KVG + FIIAE+G NH G+I +A +LI A AGA VKFQ ++ ++ Y +
Sbjct: 10 KVGEKSSIFIIAEIGVNHNGNIDLAYKLIDLASKAGADAVKFQMFYPEKLCSEIYRKDEI 69
Query: 468 DNHNSWGKTYGDHKKHLEFSESQYRELFKYAHEIGILFTASAMDMVSFDFLVNLKVPFIK 647
+ + ++ + KK L Y + +G+ F + D S D ++NL IK
Sbjct: 70 EMLKKYVLSFENMKK-----------LRDYTYSLGLEFIVTPFDFKSLDDIINLDCSAIK 118
Query: 648 IGSGDSNNLLFLKYAASKKLPLIISTGMVDKSAV-KTIYDIISSEHKQFCLLHXISAYPV 824
+ SG+ ++ F+K AAS PLIISTG + S V + + I S ++ +LH +S YP
Sbjct: 119 VASGELTHIPFIKKAASYNKPLIISTGASNLSDVERAVIAIKSVADEKISILHCVSTYPS 178
Query: 825 PFEDCNLTVLQDYKI 869
P E NL L+ ++
Sbjct: 179 PDECLNLRALKTLEV 193
>UniRef50_Q4VKA5 Cluster: NeuNAc condensing enzyme; n=54; cellular
organisms|Rep: NeuNAc condensing enzyme - Escherichia
coli
Length = 350
Score = 101 bits (241), Expect = 7e-20
Identities = 72/208 (34%), Positives = 108/208 (51%), Gaps = 12/208 (5%)
Frame = +3
Query: 312 FIIAEVGQNHQGDIGIAKQLIKAAKDAGASCVKFQKTCLKEKFTKKYLERSYDNHNSWG- 488
+I+AE+G NH GD +AK+++K AK AG VKFQ T E+ KY ++ G
Sbjct: 9 YIVAEIGCNHNGDFELAKKMVKEAKSAGVDAVKFQ-TFKAEQLISKYAPKAEYQIKVTGN 67
Query: 489 -KTYGDHKKHLEFSESQYRELFKYAHEIGILFTASAMDMVSFDFLVNLKVPFIKIGSGDS 665
+T + + LE ++ +L +YA E+G+ ++ D S DFL + KI SG+
Sbjct: 68 EETQLEMTRKLELPYDEFIKLEEYAKELGLDVFSTPFDFDSIDFLASRNQKVWKIPSGEL 127
Query: 666 NNLLFLKYAASKKLP-----LIISTGM--VDK--SAVKTIYDIISSEHKQFCLLHXISAY 818
NL +L+ A KLP +++STGM VD+ A+K D H+ +LH + Y
Sbjct: 128 LNLPYLEKIA--KLPIEDKKIVLSTGMATVDEINLALKVFID-NGITHRNITILHCNTEY 184
Query: 819 PVPFEDCNLTVLQDY-KILLMYLLXIRD 899
P PFED NL + + KI Y + D
Sbjct: 185 PTPFEDVNLNTISGFKKIFSQYNIGFSD 212
>UniRef50_Q3XXA4 Cluster: N-acetylneuraminate synthase; n=1;
Enterococcus faecium DO|Rep: N-acetylneuraminate
synthase - Enterococcus faecium DO
Length = 335
Score = 100 bits (239), Expect = 1e-19
Identities = 64/186 (34%), Positives = 89/186 (47%), Gaps = 1/186 (0%)
Frame = +3
Query: 312 FIIAEVGQNHQGDIGIAKQLIKAAKDAGASCVKFQKTCLKEKFTKKYLERSYDNHN-SWG 488
++IAE+G NH G + +A + I AK+ GA+ VKFQ + +KK Y N
Sbjct: 7 YVIAEIGVNHNGSLDLALESIDKAKECGANAVKFQTFKTNKLVSKKAPMAKYQKDNLKED 66
Query: 489 KTYGDHKKHLEFSESQYRELFKYAHEIGILFTASAMDMVSFDFLVNLKVPFIKIGSGDSN 668
+ + K LE S+S + + Y + I F ++ D S DFL + V KIGSGD
Sbjct: 67 SSQFEMLKKLELSQSDFIRIKDYCIQNKIDFLSTPFDEESADFLKQIGVQGFKIGSGDLT 126
Query: 669 NLLFLKYAASKKLPLIISTGMVDKSAVKTIYDIISSEHKQFCLLHXISAYPVPFEDCNLT 848
NL FL+ LP+++STGM D V D +LH S YP ED NL
Sbjct: 127 NLPFLRKIDMYGLPVLLSTGMADIHEVSEAVDCFID--SPVTILHCTSNYPASSEDINLL 184
Query: 849 VLQDYK 866
+ K
Sbjct: 185 AINTLK 190
>UniRef50_A3V3D1 Cluster: Polysialic acid capsule biosynthesis
protein SiaC; n=3; Bacteria|Rep: Polysialic acid capsule
biosynthesis protein SiaC - Loktanella vestfoldensis
SKA53
Length = 343
Score = 99.5 bits (237), Expect = 2e-19
Identities = 55/193 (28%), Positives = 102/193 (52%)
Frame = +3
Query: 288 KVGGNNPCFIIAEVGQNHQGDIGIAKQLIKAAKDAGASCVKFQKTCLKEKFTKKYLERSY 467
K+G +P +IAE+G NH GD+ +AK++++ A +G VK Q + ++ T++ +
Sbjct: 7 KIGPEHPPLVIAEIGINHGGDLAVAKEMVRLAALSGCEMVKHQTHIIADEMTEEARQIFP 66
Query: 468 DNHNSWGKTYGDHKKHLEFSESQYRELFKYAHEIGILFTASAMDMVSFDFLVNLKVPFIK 647
N + + + + S + EL +Y +G+++ ++ + DFL +L VP K
Sbjct: 67 PNADV---SIWEVMEACALSLDEEAELKRYTESLGMIWISTPFSRAAADFLQDLDVPAFK 123
Query: 648 IGSGDSNNLLFLKYAASKKLPLIISTGMVDKSAVKTIYDIISSEHKQFCLLHXISAYPVP 827
IGSG+++NL +++ A P+I+STGM +++ I+ + LL + YP P
Sbjct: 124 IGSGEADNLPLIRHIARMGKPVIMSTGMQSIESIRASVAILDGAGVDYALLECTNLYPSP 183
Query: 828 FEDCNLTVLQDYK 866
E +L + D K
Sbjct: 184 PEIVSLQGVTDLK 196
>UniRef50_Q73P39 Cluster: NeuB family protein; n=1; Treponema
denticola|Rep: NeuB family protein - Treponema denticola
Length = 379
Score = 98.7 bits (235), Expect = 4e-19
Identities = 65/188 (34%), Positives = 98/188 (52%), Gaps = 2/188 (1%)
Frame = +3
Query: 303 NPCFIIAEVGQNHQGDIGIAKQLIKAAKDAGASCVKFQKTCLKEKFTKKYLERSYDNHNS 482
NP IAE+G +H G I A+ LI A +AGA VKFQ E + Y + +
Sbjct: 19 NP-LTIAEIGTSHNGSIQKARNLIDVAAEAGAKAVKFQIVYADEIL---HPNTGYVDLPT 74
Query: 483 WGKTYGDHKKHLEFSESQYRELFKYAHEIGILFTASAMDMVSFDFLVNLKVPFIKIGSGD 662
D K LE S Y+EL +Y+ +LF+AS S + L LK FIKI S +
Sbjct: 75 GKIPLYDRFKSLELPVSFYKELAEYSRSKKLLFSASPFGFRSAEELAALKPDFIKIASPE 134
Query: 663 SNNLLFLKYAASKKLPLIISTGMVDKSAVKTIYDIISSEHKQ--FCLLHXISAYPVPFED 836
N + LKY A +P+I+S+G+ ++ + SE+K LLH I++YP P ++
Sbjct: 135 LNYVQLLKYCAGFNIPMILSSGVSILKDIEKAVSFLRSENKDLPLALLHCITSYPAPEKE 194
Query: 837 CNLTVLQD 860
N++V+++
Sbjct: 195 YNVSVIKN 202
>UniRef50_Q46675 Cluster: NeuB protein; n=8; Bacteria|Rep: NeuB
protein - Escherichia coli
Length = 346
Score = 98.3 bits (234), Expect = 5e-19
Identities = 64/193 (33%), Positives = 95/193 (49%), Gaps = 8/193 (4%)
Frame = +3
Query: 312 FIIAEVGQNHQGDIGIAKQLIKAAKDAGASCVKFQKTCLKEKFTKKYLERSYDNHNSWGK 491
+I+AE+G NH G + IA+++I AK+AG + VKFQ T +K ++ + G+
Sbjct: 5 YIVAEIGCNHNGSVDIAREMILKAKEAGVNAVKFQ-TFKADKLISAIAPKAEYQIKNTGE 63
Query: 492 TYG--DHKKHLEFSESQYRELFKYAHEIGILFTASAMDMVSFDFLVNLKVPFIKIGSGDS 665
+ K LE Y L +YA + + ++ D S DFL +LK KI SG+
Sbjct: 64 LESQLEMTKKLEMKYDDYLHLMEYAVSLNLDVFSTPFDEDSIDFLASLKQKIWKIPSGEL 123
Query: 666 NNLLFLKYAASKKLP---LIISTGMVDKSAVKTIYDIISSEH---KQFCLLHXISAYPVP 827
NL +L+ A +P +IISTGM +K I + +LH + YP P
Sbjct: 124 LNLPYLEKIAKLPIPDKKIIISTGMATIDEIKQSVSIFINNKVPVGNITILHCNTEYPTP 183
Query: 828 FEDCNLTVLQDYK 866
FED NL + D K
Sbjct: 184 FEDVNLNAINDLK 196
>UniRef50_Q0A628 Cluster: N-acylneuraminate-9-phosphate synthase;
n=1; Alkalilimnicola ehrlichei MLHE-1|Rep:
N-acylneuraminate-9-phosphate synthase - Alkalilimnicola
ehrlichei (strain MLHE-1)
Length = 348
Score = 97.9 bits (233), Expect = 6e-19
Identities = 59/188 (31%), Positives = 92/188 (48%)
Frame = +3
Query: 291 VGGNNPCFIIAEVGQNHQGDIGIAKQLIKAAKDAGASCVKFQKTCLKEKFTKKYLERSYD 470
+G N+P ++IAE G +H + +A+ + A+ AGA +KFQ E T+ D
Sbjct: 11 IGPNHPPYVIAEAGVHHYDSLELARAYVLEARKAGADAIKFQTYTADELVTRWAPLYWTD 70
Query: 471 NHNSWGKTYGDHKKHLEFSESQYRELFKYAHEIGILFTASAMDMVSFDFLVNLKVPFIKI 650
K+ L S ++YR LF YA E+GI ++ D S D L L + K+
Sbjct: 71 ARFETQHQVFSTKRGL--SPTEYRSLFDYARELGITPLSTPFDPASVDLLDGLGMAAFKV 128
Query: 651 GSGDSNNLLFLKYAASKKLPLIISTGMVDKSAVKTIYDIISSEHKQFCLLHXISAYPVPF 830
S D + L+ A K P+++STG + V++ +++ SE LLH AYP P
Sbjct: 129 ASADITHRPLLQDIAGKGKPVLLSTGAASMAEVRSALEVLESEGVPVALLHCSLAYPTPV 188
Query: 831 EDCNLTVL 854
+ NL+ L
Sbjct: 189 DQANLSRL 196
>UniRef50_Q04TP3 Cluster: N-acetylneuraminic acid (Sialic acid)
synthetase; n=6; Bacteria|Rep: N-acetylneuraminic acid
(Sialic acid) synthetase - Leptospira borgpetersenii
serovar Hardjo-bovis (strain JB197)
Length = 364
Score = 97.9 bits (233), Expect = 6e-19
Identities = 61/187 (32%), Positives = 100/187 (53%), Gaps = 4/187 (2%)
Frame = +3
Query: 312 FIIAEVGQNHQGDIGIAKQLIKAAKDAGASCVKFQ---KTCLKEKFTKKYLERSYDNHNS 482
++IAE+G NH+G I IAK+LI AKD GA KFQ L K + Y +R+ + S
Sbjct: 29 YVIAEIGVNHEGSIDIAKRLIDEAKDGGADGAKFQTYKAETLASKNSPSYWDRTQEPTAS 88
Query: 483 WGKTYGDHKKHLEFSESQYRELFKYAHEIGILFTASAMDMVSFDFLVNLKVPFIKIGSGD 662
+ + KK+ F +Y L K+ +GI F ++ D+ + + L + ++PFIK+ S D
Sbjct: 89 QFELF---KKYDSFGWKEYEILAKHCQSVGIDFLSTPFDLEAVEHLAS-QMPFIKVASAD 144
Query: 663 SNNLLFLKYAASKKLPLIISTGMVDKSAVK-TIYDIISSEHKQFCLLHXISAYPVPFEDC 839
++ L+ A P+I+STG + + ++ ++ + LLH I YP E+
Sbjct: 145 ITSVPLLRSVAKYSKPVILSTGSSTIPEIDFAMRELHANGANEIILLHCILNYPTKPENA 204
Query: 840 NLTVLQD 860
NL ++QD
Sbjct: 205 NLGMIQD 211
>UniRef50_Q8TJL5 Cluster: N-acetylneuraminic acid phosphate
synthase; n=11; cellular organisms|Rep:
N-acetylneuraminic acid phosphate synthase -
Methanosarcina acetivorans
Length = 286
Score = 95.5 bits (227), Expect = 3e-18
Identities = 59/180 (32%), Positives = 98/180 (54%), Gaps = 6/180 (3%)
Frame = +3
Query: 315 IIAEVGQNHQGDIGIAKQLIK-AAKDAGASCVKFQKTCLKEKFTKKYLERSYD-NHNSWG 488
+IAE+G NH+G++ IA ++IK AA+ VKFQK E T + + HNS+G
Sbjct: 6 VIAEIGCNHKGEMEIAHEMIKVAAQFCKVDIVKFQKRTPVELLTPEEYNAPHPVPHNSYG 65
Query: 489 KTYGDHKKHLEFSESQYRELFKYAHEIGILFTASAMDMVSFDFLVNLKVPFIKIGSGDSN 668
KTYG+H++ LEF+ Q+++L K+ + G++++ S D+ + +V++ IKI S +
Sbjct: 66 KTYGEHREFLEFNLDQHKQLKKWCDDWGVVYSTSVWDLTAAKEIVSINPELIKIPSACNL 125
Query: 669 NLLFLKYAASK-KLPLIISTGMV---DKSAVKTIYDIISSEHKQFCLLHXISAYPVPFED 836
L+Y + + +S GM ++ V T ++ K + S YPVPFED
Sbjct: 126 KFDMLEYLCKEYDGEIHLSFGMTTNEEEEKVVTFFE-DRGRGKDLIIYSCTSGYPVPFED 184
>UniRef50_Q9A4G6 Cluster: NeuB protein, putative; n=17;
Bacteria|Rep: NeuB protein, putative - Caulobacter
crescentus (Caulobacter vibrioides)
Length = 356
Score = 94.7 bits (225), Expect = 6e-18
Identities = 58/194 (29%), Positives = 96/194 (49%), Gaps = 3/194 (1%)
Frame = +3
Query: 288 KVGGNNPCFIIAEVGQNHQGDIGIAKQLIKAAKDAGASCVKFQKTCLKEKFTKKYLERSY 467
K+G ++ ++I E+ NH G + ++ AA D G +K Q T + T +
Sbjct: 18 KIGADHSPYVICELSGNHNGSLERCLAMVDAAADTGCDAIKIQ-TYTADTITLDVDRPEF 76
Query: 468 DNHNS-W-GKTYGDHKKHLEFSESQYRELFKYAHEIGILFTASAMDMVSFDFLVNLKVPF 641
H W G+T + + + +F+ A + G+ +S D + D L +L P
Sbjct: 77 KIHGGLWDGRTLYELYEEAHTPFEWHAAIFERARQRGVTIFSSPFDETAVDLLDSLGAPA 136
Query: 642 IKIGSGDSNNLLFLKYAASKKLPLIISTGMVDKSAVKTIYD-IISSEHKQFCLLHXISAY 818
KI S ++ +L +KYAA+K PLIISTGM + + ++T D +S+ LLH +S+Y
Sbjct: 137 FKIASFEAVDLPLIKYAAAKGKPLIISTGMANLTEMQTALDTALSAGAPGVLLLHCVSSY 196
Query: 819 PVPFEDCNLTVLQD 860
P F D N+ + D
Sbjct: 197 PATFADANVRTVPD 210
>UniRef50_Q1PVV9 Cluster: Similarity to N-acetyl neuramic acid
synthetase NeuB; n=1; Candidatus Kuenenia
stuttgartiensis|Rep: Similarity to N-acetyl neuramic
acid synthetase NeuB - Candidatus Kuenenia
stuttgartiensis
Length = 277
Score = 93.9 bits (223), Expect = 1e-17
Identities = 62/189 (32%), Positives = 91/189 (48%)
Frame = +3
Query: 300 NNPCFIIAEVGQNHQGDIGIAKQLIKAAKDAGASCVKFQKTCLKEKFTKKYLERSYDNHN 479
+N ++IAE+G NH GD+ AK+LI +A G VKFQ T L EK K N
Sbjct: 12 DNKVYVIAEIGLNHGGDMNTAKRLIDSASKTGVDAVKFQ-TYLTEKRVPK---------N 61
Query: 480 SWGKTYGDHKKHLEFSESQYRELFKYAHEIGILFTASAMDMVSFDFLVNLKVPFIKIGSG 659
S D K E ++EL Y I F ++ D S DFL ++ K+ S
Sbjct: 62 S---PIFDILKKCELPFEVFKELKDYTETYNIEFFSTPFDEESVDFLESVNCALYKVASF 118
Query: 660 DSNNLLFLKYAASKKLPLIISTGMVDKSAVKTIYDIISSEHKQFCLLHXISAYPVPFEDC 839
D N L A K +I+S GM + S ++ + I+ ++ + ++H +SAYP ED
Sbjct: 119 DVVNYKLLSKIADTKKTIIMSVGMANLSEIEGAFKILKNKTDKLAIMHCVSAYPTKEEDA 178
Query: 840 NLTVLQDYK 866
NL+ + K
Sbjct: 179 NLSAIYTLK 187
>UniRef50_Q93NQ2 Cluster: NnaB; n=7; Bacteria|Rep: NnaB -
Escherichia coli
Length = 346
Score = 91.1 bits (216), Expect = 7e-17
Identities = 55/186 (29%), Positives = 98/186 (52%), Gaps = 8/186 (4%)
Frame = +3
Query: 312 FIIAEVGQNHQGDIGIAKQLIKAAKDAGASCVKFQKTCLKEKFTKKYLERSYDNHNSWG- 488
+I+AE+G NH GD +AK++++ AK AG VKFQ T ++ KY ++ G
Sbjct: 5 YIVAEIGCNHNGDFNLAKKMVEEAKKAGVDAVKFQ-TFKADQLISKYAPKAEYQIKVTGN 63
Query: 489 -KTYGDHKKHLEFSESQYRELFKYAHEIGILFTASAMDMVSFDFLVNLKVPFIKIGSGDS 665
++ + + LE ++ +L +YA E+G+ ++ D S DFL + KI SG+
Sbjct: 64 QESQLEMTRKLELPYEEFIKLEEYAKELGLDVFSTPFDFESIDFLASRNQKMWKIPSGEL 123
Query: 666 NNLLFLKYAASKKL---PLIISTGMVDKSAVKTIYDIISSE---HKQFCLLHXISAYPVP 827
NL +L+ + + +++STGM +K ++++ ++ +LH + YP P
Sbjct: 124 LNLPYLEKISRLPIEGKEIVLSTGMATIEEIKASVNVLTKNGMAPEKITILHCNTEYPTP 183
Query: 828 FEDCNL 845
+ED NL
Sbjct: 184 YEDVNL 189
>UniRef50_A0LYV7 Cluster: N-acetylneuraminate synthase; n=1;
Gramella forsetii KT0803|Rep: N-acetylneuraminate
synthase - Gramella forsetii (strain KT0803)
Length = 332
Score = 91.1 bits (216), Expect = 7e-17
Identities = 58/184 (31%), Positives = 87/184 (47%)
Frame = +3
Query: 315 IIAEVGQNHQGDIGIAKQLIKAAKDAGASCVKFQKTCLKEKFTKKYLERSYDNHNSWGKT 494
+IAEVGQ H+G +G+A I A +AG VKFQ + + LE + KT
Sbjct: 3 VIAEVGQAHEGSLGMALSYIGALAEAGVDAVKFQVHIAEAE--SSILEPFRIKFSEQDKT 60
Query: 495 YGDHKKHLEFSESQYRELFKYAHEIGILFTASAMDMVSFDFLVNLKVPFIKIGSGDSNNL 674
D+ K +EFS +++ + K + + F AS + D L + V KIGSG+ NN
Sbjct: 61 RFDYWKRMEFSTDEWKLIKKTCEDNNVEFLASPFSNAAVDLLEEVGVKRYKIGSGEVNNF 120
Query: 675 LFLKYAASKKLPLIISTGMVDKSAVKTIYDIISSEHKQFCLLHXISAYPVPFEDCNLTVL 854
L L+ A +IIS+GM + + F LL ++YP + L V+
Sbjct: 121 LLLEKIAKTGKQVIISSGMSSFDELDATVSFLRERKISFSLLQCTTSYPTTPANYGLNVI 180
Query: 855 QDYK 866
Q+ K
Sbjct: 181 QELK 184
>UniRef50_Q89HL9 Cluster: Blr5971 protein; n=1; Bradyrhizobium
japonicum|Rep: Blr5971 protein - Bradyrhizobium
japonicum
Length = 641
Score = 90.6 bits (215), Expect = 9e-17
Identities = 58/185 (31%), Positives = 81/185 (43%)
Frame = +3
Query: 291 VGGNNPCFIIAEVGQNHQGDIGIAKQLIKAAKDAGASCVKFQKTCLKEKFTKKYLERSYD 470
+G PC++IAEVG NH GD A L+ AA AGA C KFQ L E + L D
Sbjct: 19 LGDGEPCYVIAEVGNNHNGDFDRAIALVDAAVAAGADCAKFQMRKLDEVYRASSLS-GKD 77
Query: 471 NHNSWGKTYGDHKKHLEFSESQYRELFKYAHEIGILFTASAMDMVSFDFLVNLKVPFIKI 650
+ + T D + E + Q +++ Y GI + + D S L V K+
Sbjct: 78 DDLAVEYTL-DLLRRFELTTEQQKKIADYCASKGIQYLCTPWDAKSVAVLEGFGVQAYKV 136
Query: 651 GSGDSNNLLFLKYAASKKLPLIISTGMVDKSAVKTIYDIISSEHKQFCLLHXISAYPVPF 830
S D NL L + LI+STGM +K + + + LLH S YP
Sbjct: 137 ASADLTNLPLLARLIATGKTLIVSTGMSTTEEIKAAAEFLDERKAGYVLLHCQSTYPAAL 196
Query: 831 EDCNL 845
+ +L
Sbjct: 197 HNIHL 201
>UniRef50_Q12JI6 Cluster: N-acetylneuraminic acid synthase-like
protein; n=1; Shewanella denitrificans OS217|Rep:
N-acetylneuraminic acid synthase-like protein -
Shewanella denitrificans (strain OS217 / ATCC BAA-1090 /
DSM 15013)
Length = 359
Score = 90.6 bits (215), Expect = 9e-17
Identities = 58/205 (28%), Positives = 101/205 (49%), Gaps = 4/205 (1%)
Frame = +3
Query: 258 MLEVKITEDVK-VGGNNPCFIIAEVGQNHQGDIGIAKQLIKAAKDAGASCVKFQKTCLKE 434
M + IT D + +G +IIAE+ NH+G + A +I AA +G +K Q T
Sbjct: 1 MFKASITIDGRHIGPEYQPYIIAELSGNHKGSLSQALAMIDAAAASGVDAIKIQ-TYTAN 59
Query: 435 KFTKKYLERSYD-NHNSW-GKTYGDHKKHLEFSESQYRELFKYAHEIGILFTASAMDMVS 608
T ++ + N W G+T D + ++ LF++A + + +S D+ +
Sbjct: 60 TITLQHDGPEFRINGGLWKGRTLFDLYEEAHTPWEWHKSLFEHAKKQNVTLFSSPFDLKA 119
Query: 609 FDFLVNLKVPFIKIGSGDSNNLLFLKYAASKKLPLIISTGMVDKSAVKTIYDIISSE-HK 785
+ L + + P KI S + N++ + AA P+++STG+ + ++ + +++
Sbjct: 120 IELLESCECPAYKISSFEINDIGLIMAAAKTGKPIVMSTGLATLAEIEEAVEAVANAGGT 179
Query: 786 QFCLLHXISAYPVPFEDCNLTVLQD 860
Q LLH IS YP P EDCNL + D
Sbjct: 180 QLALLHCISGYPTPIEDCNLKTVAD 204
>UniRef50_A3PE56 Cluster: Sialic acid synthase; n=1; Prochlorococcus
marinus str. MIT 9301|Rep: Sialic acid synthase -
Prochlorococcus marinus (strain MIT 9301)
Length = 341
Score = 90.6 bits (215), Expect = 9e-17
Identities = 53/186 (28%), Positives = 97/186 (52%), Gaps = 6/186 (3%)
Frame = +3
Query: 315 IIAEVGQNHQGDIGIAKQLIKAAKDAGASCVKFQKTCLKEKFTKKYLERSYDNHNSWGKT 494
+IAE G NH G + +A +L++ AK +GA +KFQ + + Y ++ K+
Sbjct: 5 VIAEAGVNHNGSLDLALKLVEEAKLSGADSIKFQTFKSESLASFSAPLAQYQKKSNSYKS 64
Query: 495 YGDHKKHLEFSESQYRELFKYAHEIGILFTASAMDMVSFDFLVNLKVPFIKIGSGDSNNL 674
D K LE ++ + +F + +EIGI F +S + FL++L + IKI SG+ N
Sbjct: 65 QIDMLKSLELTDKDTKRIFSFCNEIGIEFMSSPFGVDELHFLLDLGMLSIKIPSGEITNY 124
Query: 675 LFL----KYAASKKLPLIISTGMVDKSAVKTIYDIISSEH--KQFCLLHXISAYPVPFED 836
+ K+ + + +++STGM ++ ++ + ++ ++H +S+YP P +D
Sbjct: 125 ALISEIGKFISEGNINVLLSTGMSSLGDIEEALSLLRFKETLERITIMHCVSSYPAPNKD 184
Query: 837 CNLTVL 854
NL VL
Sbjct: 185 LNLKVL 190
>UniRef50_Q2N2P7 Cluster: NeuB; n=7; Proteobacteria|Rep: NeuB -
Aeromonas hydrophila
Length = 345
Score = 90.2 bits (214), Expect = 1e-16
Identities = 61/198 (30%), Positives = 96/198 (48%), Gaps = 3/198 (1%)
Frame = +3
Query: 291 VGGNNPCFIIAEVGQNHQGDIGIAKQLIKAAKDAGASCVKFQKTCLKEKFTKKYLERSYD 470
+G ++IAE+ NH G++ A ++ AAK AGAS VK Q T + T K +
Sbjct: 8 IGPAQAPYVIAELSANHNGNLERALAIMTAAKAAGASAVKLQ-TYRPDTITLKSDRPEFQ 66
Query: 471 NHNS-W-GKTYGDHKKHLEFSESQYRELFKYAHEIGILFTASAMDMVSFDFLVNLKVPFI 644
H W G + D + ++ LF E+G+ +S D + D L +L P
Sbjct: 67 IHGGLWDGHSLYDLYEWAHTPWEWHQALFAKGRELGLTVFSSPFDFSAVDLLESLDCPAY 126
Query: 645 KIGSGDSNNLLFLKYAASKKLPLIISTGMVDKSAVKTIYDI-ISSEHKQFCLLHXISAYP 821
KI S + +L ++YAA PLI+STGM +++ + ++ + Q LLH +S YP
Sbjct: 127 KIASFELVDLPLIRYAAQTGKPLIMSTGMANEAEIAAAVEMALKHGSGQLALLHCVSGYP 186
Query: 822 VPFEDCNLTVLQDYKILL 875
P + NL + + LL
Sbjct: 187 APAAEYNLRTIPMLRQLL 204
>UniRef50_A2C5V5 Cluster: Sialic acid synthase; n=1; Prochlorococcus
marinus str. MIT 9303|Rep: Sialic acid synthase -
Prochlorococcus marinus (strain MIT 9303)
Length = 335
Score = 90.2 bits (214), Expect = 1e-16
Identities = 60/188 (31%), Positives = 90/188 (47%), Gaps = 7/188 (3%)
Frame = +3
Query: 315 IIAEVGQNHQGDIGIAKQLIKAAKDAGASCVKFQKTCLKEKFTKKYLERSYDNHNSWGKT 494
IIAE G NH G+I A +LI +AK AGA +KFQ E + + Y + T
Sbjct: 5 IIAEAGVNHNGEIQNAYRLIDSAKFAGADAIKFQSFSSIELTAENAPKAKYQQMYADRST 64
Query: 495 YGDHKKHLEFSESQYRELFKYAHEIGILFTASAMDMVSFDFLVNLKVPFIKIGSGDSNNL 674
+ LE +E +++ + Y +I I F ++A D L+ LKV IK+ SG+ +
Sbjct: 65 QREMLARLELNEMEHQLIADYCEKIEIEFLSTAFGQSQLDLLIKLKVQAIKVASGEITHW 124
Query: 675 LFLKYAASK----KLPLIISTGMVDKSAVKTIYDIISSEH---KQFCLLHXISAYPVPFE 833
LK A K L + +STGM + ++ DI E + +LH S YP P+
Sbjct: 125 PLLKEMAKKAYENNLDVYLSTGMSEIKEIQDALDIFIKEDISLGKIFILHCTSHYPAPYN 184
Query: 834 DCNLTVLQ 857
N+ L+
Sbjct: 185 AVNMKALR 192
>UniRef50_Q97H26 Cluster: Sialic acid synthase; n=14; cellular
organisms|Rep: Sialic acid synthase - Clostridium
acetobutylicum
Length = 350
Score = 89.0 bits (211), Expect = 3e-16
Identities = 65/201 (32%), Positives = 105/201 (52%), Gaps = 8/201 (3%)
Frame = +3
Query: 288 KVGGNNPCFIIAEVGQNHQGDIGIAKQLIKAAKDAGASCVKFQKTCLKEKFTKKYLERSY 467
K+G FIIAE+ NH D A ++IKAAK +GA +K Q T + T +
Sbjct: 11 KIGEGQRTFIIAEMSANHNQDFDRAVEIIKAAKRSGADAIKLQ-TYTPDTITFDSDNEYF 69
Query: 468 DNHNS--WGKTYGDHKKHLE-FSESQYR-ELFKYAHEIGILFTASAMDMVSFDFLVNLKV 635
W T HK + E ++ Q++ +L + A E G++ +S D S DFL ++V
Sbjct: 70 QIKQGTIWDGTTL-HKLYEEAYTPWQWQPKLKEIAEEEGLICFSSPFDNTSVDFLEKMEV 128
Query: 636 PFIKIGSGDSNNLLFLKYAASKKLPLIISTGMVDKSAVKTIYDIISSEHKQ----FCLLH 803
P K+ S + ++ F++Y ASK P+I+STG+ + + IY+ +++ +Q LL
Sbjct: 129 PAYKVASFELTDIPFIEYIASKGKPVIMSTGIAE---MGEIYEAVAACRRQGNENVILLK 185
Query: 804 XISAYPVPFEDCNLTVLQDYK 866
S+YP P ED NL + + +
Sbjct: 186 CSSSYPSPLEDINLKTIPNMR 206
>UniRef50_Q5R082 Cluster: Sialic acid synthase; n=47; Bacteria|Rep:
Sialic acid synthase - Idiomarina loihiensis
Length = 352
Score = 88.2 bits (209), Expect = 5e-16
Identities = 51/180 (28%), Positives = 90/180 (50%)
Frame = +3
Query: 288 KVGGNNPCFIIAEVGQNHQGDIGIAKQLIKAAKDAGASCVKFQKTCLKEKFTKKYLERSY 467
++G ++ ++AE+G NH+G + A +++ AA AGA +K Q ++++ + +
Sbjct: 17 EIGYDHDPVVVAEIGINHEGSLETAYEMVDAAVSAGAEIIKHQTHVVEDEMSAD--AKKV 74
Query: 468 DNHNSWGKTYGDHKKHLEFSESQYRELFKYAHEIGILFTASAMDMVSFDFLVNLKVPFIK 647
N+ Y + + +E +L +Y G +F ++ + + L + V K
Sbjct: 75 IPGNADVSIY-EIMERCALNEEDETKLKEYVESKGAIFISTPFSRAAAERLERMGVEAYK 133
Query: 648 IGSGDSNNLLFLKYAASKKLPLIISTGMVDKSAVKTIYDIISSEHKQFCLLHXISAYPVP 827
IGSG+ NN L+ AS K P+I+STGM D ++ DI Q+ LLH + YP P
Sbjct: 134 IGSGECNNYPLLELVASYKKPIILSTGMNDIPSIAKAVDIFRKHGVQYALLHCTNVYPTP 193
>UniRef50_A4B2T9 Cluster: NeuB:Antifreeze-like protein; n=1;
Alteromonas macleodii 'Deep ecotype'|Rep:
NeuB:Antifreeze-like protein - Alteromonas macleodii
'Deep ecotype'
Length = 347
Score = 88.2 bits (209), Expect = 5e-16
Identities = 55/181 (30%), Positives = 91/181 (50%), Gaps = 3/181 (1%)
Frame = +3
Query: 312 FIIAEVGQNHQGDIGIAKQLIKAAKDAGASCVKFQKTCLKEKFTKKYLERSYDNHNS-W- 485
+IIAE+ NH GD+ AK+ I A + G S +K Q T + T L+ + + W
Sbjct: 15 YIIAELSANHGGDLSRAKESITKAAEVGVSAIKIQ-TYTPDTMTLDSLQDDFIVKDGLWA 73
Query: 486 GKTYGDHKKHLEFSESQYRELFKYAHEIGILFTASAMDMVSFDFLVNLKVPFIKIGSGDS 665
G++ + + ELF +A G+ ++ D + D L +L P KI S +
Sbjct: 74 GRSLYELYTEAYTPYEWHEELFNHAKNCGVTIFSTPFDETAVDLLESLNTPAYKIASFEI 133
Query: 666 NNLLFLKYAASKKLPLIISTGMVDKSAV-KTIYDIISSEHKQFCLLHXISAYPVPFEDCN 842
+L +KY ASK P+++STGM ++ + + + + ++ + L H IS+YP ED N
Sbjct: 134 VDLPLVKYIASKNKPILMSTGMASQTEIEEAVTSVRANGDCELLLFHCISSYPAVTEDSN 193
Query: 843 L 845
L
Sbjct: 194 L 194
>UniRef50_Q5QWT8 Cluster: Sialic acid synthase; n=14; Bacteria|Rep:
Sialic acid synthase - Idiomarina loihiensis
Length = 357
Score = 87.8 bits (208), Expect = 7e-16
Identities = 57/156 (36%), Positives = 87/156 (55%), Gaps = 3/156 (1%)
Frame = +3
Query: 315 IIAEVGQNHQGDIGIAKQLIKAAKDAGASCVKFQKTCLKEKFTKKYLERSYDNHN-SWGK 491
IIAE G NH GD +A+ L+ +A AGA VKFQ K T+K + +Y N +
Sbjct: 4 IIAEAGVNHNGDAKLARDLVTSAHKAGADIVKFQTFKAKNIVTEKATQANYQKKNLGREE 63
Query: 492 TYGDHKKHLEFSESQYRELFKYAHEIGILFTASAMDMVSFDFLVN-LKVPFIKIGSGDSN 668
+ + LE S + EL Y +E+GI F ++A D S +FLVN L + +K+ SG+
Sbjct: 64 SQLAMLQRLELSHELHYELVDYCNELGIEFLSTAFDDESLNFLVNDLGLKRLKLPSGEIT 123
Query: 669 NL-LFLKYAASKKLPLIISTGMVDKSAVKTIYDIIS 773
N L LK+A + LI+STGM + ++++ +I+
Sbjct: 124 NAPLVLKHAQT-GCDLIVSTGMATMAEIESVLGVIA 158
>UniRef50_Q7NQV6 Cluster: N-acetylneuraminic acid synthase; n=7;
Proteobacteria|Rep: N-acetylneuraminic acid synthase -
Chromobacterium violaceum
Length = 361
Score = 86.6 bits (205), Expect = 2e-15
Identities = 54/145 (37%), Positives = 78/145 (53%), Gaps = 2/145 (1%)
Frame = +3
Query: 303 NPCFIIAEVGQNHQGDIGIAKQLIKAAKDAGASCVKFQKTCLKEKFTKKYLERSYDNHNS 482
N FIIAE G NH G + +A +LI AAK+AGA VKFQ + + Y +
Sbjct: 2 NHVFIIAEAGVNHNGSLKVALELIDAAKEAGADAVKFQTFKSGAVISMDAPKAEYQKTTT 61
Query: 483 -WGKTYGDHKKHLEFSESQYRELFKYAHEIGILFTASAMDMVSFDFLV-NLKVPFIKIGS 656
++ D + LE S + +L ++ + GILF ++ D+ S + LV L VP +K+ S
Sbjct: 62 GTSESQLDMVRKLELSAEDHIQLLQHCEKRGILFLSTPFDVQSAELLVRELGVPQLKVPS 121
Query: 657 GDSNNLLFLKYAASKKLPLIISTGM 731
G+ N FL A LP+I+STGM
Sbjct: 122 GELTNAPFLLKIAGYGLPVIVSTGM 146
>UniRef50_A3Y8V9 Cluster: NeuB family protein; n=1; Marinomonas sp.
MED121|Rep: NeuB family protein - Marinomonas sp. MED121
Length = 347
Score = 86.6 bits (205), Expect = 2e-15
Identities = 58/188 (30%), Positives = 87/188 (46%), Gaps = 5/188 (2%)
Frame = +3
Query: 312 FIIAEVGQNHQGDIGIAKQLIKAAKDAGASCVKFQKTCLKEKFTKKYLERSYDNHNSWGK 491
FIIAE+ NH D +AK +I+AA G +K Q T + T +
Sbjct: 11 FIIAELSGNHNQDFALAKAMIEAAAKTGVDAIKLQ-TYTADSMTLNVRNEEFMVSAQGSL 69
Query: 492 TYGDHKKHLEFSESQ----YRELFKYAHEIGILFTASAMDMVSFDFLVNLKVPFIKIGSG 659
GD+ L S ++ LF YA +G++ +S D+ + +FL +L VP KI S
Sbjct: 70 WEGDNLYDLYAKASTPYEWHQPLFDYAKSLGLVAFSSPFDINAVNFLESLDVPIYKIASF 129
Query: 660 DSNNLLFLKYAASKKLPLIISTGMVDKSAVKTIYDIIS-SEHKQFCLLHXISAYPVPFED 836
+ +L ++ A P+I+STGM KS ++ ++ + LL S YP ED
Sbjct: 130 ELTDLPLIEAVARTGKPMIMSTGMATKSEIEEAVSLVRLIGDNEITLLKCTSTYPAKIED 189
Query: 837 CNLTVLQD 860
NL L D
Sbjct: 190 SNLITLSD 197
>UniRef50_P39625 Cluster: Spore coat polysaccharide biosynthesis
protein spsE; n=2; Bacillus|Rep: Spore coat
polysaccharide biosynthesis protein spsE - Bacillus
subtilis
Length = 373
Score = 86.6 bits (205), Expect = 2e-15
Identities = 61/189 (32%), Positives = 86/189 (45%), Gaps = 1/189 (0%)
Frame = +3
Query: 291 VGGNNPCFIIAEVGQNHQGDIGIAKQLIKAAKDAGASCVKFQKTCLKEKFTKKYLERSYD 470
VG + P FIIAE G NH G + A LI AA +AGA VKFQ + K Y
Sbjct: 11 VGKDAPVFIIAEAGINHDGKLDQAFALIDAAAEAGADAVKFQMFQADRMYQKD--PGLYK 68
Query: 471 NHNSWGKTYGDHKKHLEFSESQYRELFKYAHEIGILFTASAMDMVSFDFLVNLKVPFIKI 650
+ + +E L Y E ++F ++ D S D L + KI
Sbjct: 69 TAAGKDVSIFSLVQSMEMPAEWILPLLDYCREKQVIFLSTVCDEGSADLLQSTSPSAFKI 128
Query: 651 GSGDSNNLLFLKYAASKKLPLIISTGMVDKSAVKTIYDIISSE-HKQFCLLHXISAYPVP 827
S + N+L LKY A P+I ST + S V + I +E + Q ++H ++ YP P
Sbjct: 129 ASYEINHLPLLKYVARLNRPMIFSTAGAEISDVHEAWRTIRAEGNNQIAIMHCVAKYPAP 188
Query: 828 FEDCNLTVL 854
E NL+V+
Sbjct: 189 PEYSNLSVI 197
>UniRef50_A4MIF1 Cluster: N-acylneuraminate-9-phosphate synthase;
n=1; Geobacter bemidjiensis Bem|Rep:
N-acylneuraminate-9-phosphate synthase - Geobacter
bemidjiensis Bem
Length = 338
Score = 85.4 bits (202), Expect = 4e-15
Identities = 58/185 (31%), Positives = 91/185 (49%), Gaps = 1/185 (0%)
Frame = +3
Query: 306 PCFIIAEVGQNHQGDIGIAKQLIKAAKDAGASCVKFQKTCLKEKFTKKYLERSYDNHNSW 485
P +IIAE+G N AK L+ AA G VK Q T E + K +D N+
Sbjct: 10 PIYIIAEIGGNFT-TFEEAKALVDAAASCGVDAVKLQ-TYRAETVSSK--SAIFDMENTG 65
Query: 486 GKTYGDHKKHLEFSESQYRELFKYAHEIGILFTASAMDMVSFDFLVNLKVPFIKIGSGDS 665
+ + + E E +R++F Y G+ + ++ D L L V KIGS D+
Sbjct: 66 IASQFELFQKYEIDEELHRQVFDYIRAKGLDWFSTPSHEADVDLLDRLGVSAYKIGSDDA 125
Query: 666 NNLLFLKYAASKKLPLIISTGMVDKSAVKTIYDII-SSEHKQFCLLHXISAYPVPFEDCN 842
N+ FL+Y A+K P++++TGM V+ D+I + + + LLH +++YP E N
Sbjct: 126 VNIPFLRYVAAKGKPVLLATGMCTMQEVRESVDVILGAGNLELILLHAVTSYPTHPEHVN 185
Query: 843 LTVLQ 857
L +Q
Sbjct: 186 LLAMQ 190
>UniRef50_A1RHT0 Cluster: N-acylneuraminate-9-phosphate synthase;
n=29; cellular organisms|Rep:
N-acylneuraminate-9-phosphate synthase - Shewanella sp.
(strain W3-18-1)
Length = 349
Score = 85.4 bits (202), Expect = 4e-15
Identities = 57/203 (28%), Positives = 95/203 (46%), Gaps = 5/203 (2%)
Frame = +3
Query: 261 LEVKITEDVKVGGNNPCFIIAEVGQNHQGDIGIAKQLIKAAKDAGASCVKFQKTCLKEKF 440
++V + +G P F+IAE+ NH + AK++I AA +AGAS +K Q T +
Sbjct: 1 MQVIKVDHCHIGPGQPVFVIAELSGNHGQSLEKAKEMILAAAEAGASAIKLQ-TYTPDTI 59
Query: 441 TKKYLERSY---DNHNSW-GKTYGDHKKHLEFSESQYRELFKYAHEIGILFTASAMDMVS 608
T + D N W G++ D ++ LF YA +G++ ++ D+ +
Sbjct: 60 TLNVSHGEFFIQDQDNLWKGRSLYDLYSEAMTPWEWHQPLFDYAKSLGLVAFSTPFDLTA 119
Query: 609 FDFLVNLKVPFIKIGSGDSNNLLFLKYAASKKLPLIISTGMVDKSAVKTIYDIISSEH-K 785
++L L VP KI S ++N+ L A P+I+STGM + + ++ +
Sbjct: 120 VEYLEKLNVPCYKIASFENNDHALLAAVAKTGKPVIMSTGMAEIHELAEAVTVLKQHGCR 179
Query: 786 QFCLLHXISAYPVPFEDCNLTVL 854
LL S YP D NL+ +
Sbjct: 180 DLILLKCTSHYPAEPVDANLSTI 202
>UniRef50_Q89HJ8 Cluster: Blr5992 protein; n=2; Proteobacteria|Rep:
Blr5992 protein - Bradyrhizobium japonicum
Length = 356
Score = 85.0 bits (201), Expect = 5e-15
Identities = 56/159 (35%), Positives = 79/159 (49%), Gaps = 1/159 (0%)
Frame = +3
Query: 315 IIAEVGQNHQGDIGIAKQLIKAAKDAGASCVKFQKTCLKEKFTKKYLERSYDNHNS-WGK 491
IIAE G NH G + A L+ AA DAGA VKFQ K + Y + +
Sbjct: 7 IIAEAGVNHDGSLEKALALVDAAADAGADIVKFQTFNAKALAGGAAKKADYQQRTTDAAE 66
Query: 492 TYGDHKKHLEFSESQYRELFKYAHEIGILFTASAMDMVSFDFLVNLKVPFIKIGSGDSNN 671
+ + LE ++ + L + A E GI F ++ D S FL++LK+P IKIGSGD N
Sbjct: 67 SQLAMLERLELPQAAHHTLIERAAERGIEFLSTPFDDASLGFLLSLKLPRIKIGSGDLTN 126
Query: 672 LLFLKYAASKKLPLIISTGMVDKSAVKTIYDIISSEHKQ 788
L AA LI+STGM S ++ +++ + Q
Sbjct: 127 APLLHAAARAGATLILSTGMATLSEIEEALGVLAHGYAQ 165
>UniRef50_Q18EL3 Cluster: Sialic acid synthase; n=1; Haloquadratum
walsbyi DSM 16790|Rep: Sialic acid synthase -
Haloquadratum walsbyi (strain DSM 16790)
Length = 391
Score = 83.8 bits (198), Expect = 1e-14
Identities = 51/179 (28%), Positives = 91/179 (50%), Gaps = 4/179 (2%)
Frame = +3
Query: 321 AEVGQNHQGDIGIAKQLIKAAKDAGASCVKFQKTCLKEKFTKKYLERSYDNHNSWGKTYG 500
AE NH G+ + ++++ A DAGA +K QK ++ +T++ L +Y + +G TY
Sbjct: 98 AEFTTNHMGNFNVLMRMVEQAVDAGADYIKMQKKDVENFYTEEKLNSNY--KSPYGHTYR 155
Query: 501 DHKKHLEFSESQYRELFKYAHEIGILFTASAMDMVSFDFLVNLKVPFIKIGSGDSNN--- 671
+++K EF + + + ++ I + A+ D+ S F++ +P++K+ S +S N
Sbjct: 156 EYRKIFEFDRTDFDRFDEKCEDLDIEWFATPQDIKSLHFVLEYNMPYVKVASTNSRNDEM 215
Query: 672 LLFLKYAASKKLPLIISTGMVDKSAVKTIYDIISS-EHKQFCLLHXISAYPVPFEDCNL 845
L L+ K L+IS G S + + D +S L H +S YPVP E+ L
Sbjct: 216 LTELRDKVPKNTGLVISIG---GSTMNEVKDTLSHFPDHNIILQHCVSEYPVPPENLGL 271
>UniRef50_Q7VHQ5 Cluster: Sialic acid synthase; n=6;
Helicobacter|Rep: Sialic acid synthase - Helicobacter
hepaticus
Length = 349
Score = 83.4 bits (197), Expect = 1e-14
Identities = 63/187 (33%), Positives = 89/187 (47%), Gaps = 7/187 (3%)
Frame = +3
Query: 315 IIAEVGQNHQGDIGIAKQLIKAAKDAGASCVKFQKTCLKEKFTKKYLERSYDNHNSWGKT 494
IIAE+ NH + IAK I+A GA VK Q T E T L+ + + G T
Sbjct: 15 IIAELSANHNQSLEIAKDSIRAIAACGADGVKLQ-TYTPECLT---LQSNEPHFCISGGT 70
Query: 495 YGDHKKHLE-FSESQ-----YRELFKYAHEIGILFTASAMDMVSFDFLVNLKVPFIKIGS 656
D + E + E+Q ++ELF A E+G+L +S FL +L+ P K+ S
Sbjct: 71 LWDKRNLYELYKEAQTPWEWHKELFSLAKELGLLIFSSPFSPKGVAFLESLQCPIYKVAS 130
Query: 657 GDSNNLLFLKYAASKKLPLIISTGMVDKSAVKTIYDIISSEH-KQFCLLHXISAYPVPFE 833
+ + ++ A K P+IISTG+ +KT +I K LLH IS YP P E
Sbjct: 131 FEVMHYELIEAIAKTKKPIIISTGVATHKELKTALEICHKYGCKDITLLHCISEYPAPLE 190
Query: 834 DCNLTVL 854
NL +
Sbjct: 191 SANLLAM 197
>UniRef50_Q30V22 Cluster: N-acylneuraminate-9-phosphate synthase;
n=1; Desulfovibrio desulfuricans G20|Rep:
N-acylneuraminate-9-phosphate synthase - Desulfovibrio
desulfuricans (strain G20)
Length = 344
Score = 83.4 bits (197), Expect = 1e-14
Identities = 64/198 (32%), Positives = 89/198 (44%), Gaps = 6/198 (3%)
Frame = +3
Query: 291 VGGNNPCFIIAEVGQNHQGDIGIAKQLIKAAKDAGASCVKFQKTCLKEKFTKKYLERSYD 470
+ NP F+IAE+G NH+GD A++L+ A ++GA VK Q ++ S D
Sbjct: 5 ISDKNPVFVIAEIGGNHEGDFAYARKLVSLAIESGADAVKLQVYAGDALVSRV---ESPD 61
Query: 471 NHNSWGKTYGDHKKHLEFSESQYRELFKYAHEIGILFTASAMDMVSFDFLVNLKVPFIKI 650
+ H K E S QY L G+ F ASA D + + V K
Sbjct: 62 RNR--------HFKKFELSRGQYEALIDMCRHAGVQFMASAWDRERLGW-IEPHVRIHKA 112
Query: 651 GSGDSNNLLFLKYAASKKLPLIISTGMVD----KSAVKTIYDIISSEHKQ--FCLLHXIS 812
GSGD L+ S PL++STG+ ++AV+ I + SS Q LL S
Sbjct: 113 GSGDLTAYPMLRALVSTGKPLVLSTGLSTMPEVEAAVRYIGSLDSSYITQGKLALLQCSS 172
Query: 813 AYPVPFEDCNLTVLQDYK 866
AYP P D NL V+ +
Sbjct: 173 AYPCPDGDANLNVMHSLR 190
>UniRef50_Q1GST3 Cluster: N-acylneuraminate-9-phosphate synthase;
n=2; Alphaproteobacteria|Rep:
N-acylneuraminate-9-phosphate synthase - Sphingopyxis
alaskensis (Sphingomonas alaskensis)
Length = 350
Score = 83.0 bits (196), Expect = 2e-14
Identities = 56/190 (29%), Positives = 85/190 (44%), Gaps = 9/190 (4%)
Frame = +3
Query: 312 FIIAEVGQNHQGDIGIAKQLIKAAKDAGASCVKFQKTCLKEKFTKKYLERSYDNHNSWGK 491
F+IAE G NH G + A +L+ A +AGA VKFQ E T + +Y +
Sbjct: 12 FVIAEAGVNHDGSLDKALRLVDIAVEAGADAVKFQTFRTDEVVTPDAAKAAYQQRQTGAG 71
Query: 492 TYGDHKKHLEFSESQYRELFKYAHEIGILFTASAMDMVSFDFLVNLKVPFIKIGSGDSNN 671
T + + LE ++ + L ++ E GI F ++ + D L+ L + IKI SG+ N
Sbjct: 72 TQYEMIRALELDDAAHERLARHCAERGIEFMSTPFAPWAVDMLLGLGMRRIKIASGEIVN 131
Query: 672 LLFLKYAASKKLPLIISTGMVDKSAVKTIYDIISSEHK---------QFCLLHXISAYPV 824
+ A P+I+STGM + + V D I + +LH S YP
Sbjct: 132 KPLIDKVAGSGRPIILSTGMAEMAEVVRAVDWIRTAQSAAGIAMSPGDLVVLHCTSEYPA 191
Query: 825 PFEDCNLTVL 854
P NL +
Sbjct: 192 PAASVNLRAM 201
>UniRef50_Q7MPQ0 Cluster: Sialic acid synthase; n=3;
Proteobacteria|Rep: Sialic acid synthase - Vibrio
vulnificus (strain YJ016)
Length = 357
Score = 81.4 bits (192), Expect = 6e-14
Identities = 53/155 (34%), Positives = 80/155 (51%), Gaps = 2/155 (1%)
Frame = +3
Query: 315 IIAEVGQNHQGDIGIAKQLIKAAKDAGASCVKFQKTCLKEKFTKKYLERSYDNHNSW-GK 491
IIAE G NH GD +A +L+ AA AGA VKFQ K T++ + Y N+ +
Sbjct: 4 IIAEAGVNHNGDEALAFKLVDAAHQAGADIVKFQTFKAKNLVTEQAKQADYQVANTQKQE 63
Query: 492 TYGDHKKHLEFSESQYRELFKYAHEIGILFTASAMDMVSFDFLVN-LKVPFIKIGSGDSN 668
+ LE S + + +L K+ +GI F ++A D S DFLVN L + +K+ SG+
Sbjct: 64 SQLAMLSRLELSYAAHHQLVKHCESLGIEFLSTAFDSESLDFLVNDLGLTRLKLPSGELT 123
Query: 669 NLLFLKYAASKKLPLIISTGMVDKSAVKTIYDIIS 773
N + A LI+STGM + ++ +I+
Sbjct: 124 NAPLVLEHARTGCDLIVSTGMATLAEIEMALGVIA 158
>UniRef50_A6W187 Cluster: N-acylneuraminate-9-phosphate synthase;
n=2; Proteobacteria|Rep: N-acylneuraminate-9-phosphate
synthase - Marinomonas sp. MWYL1
Length = 343
Score = 81.0 bits (191), Expect = 8e-14
Identities = 54/188 (28%), Positives = 88/188 (46%), Gaps = 5/188 (2%)
Frame = +3
Query: 312 FIIAEVGQNHQGDIGIAKQLIKAAKDAGASCVKFQKTCLKEKFTKKYLERSY---DNHNS 482
FIIAE+ NH D +AK +I AA +AG +K Q T + T + ++ +
Sbjct: 11 FIIAELSGNHDQDFELAKAMIHAAAEAGVDAIKLQ-TYTPDTMTLDVRHGEFMVSESDSL 69
Query: 483 W-GKTYGDHKKHLEFSESQYRELFKYAHEIGILFTASAMDMVSFDFLVNLKVPFIKIGSG 659
W G D K ++ LF+ A +G++ +S D+ + FL ++ VP KI S
Sbjct: 70 WRGSNLYDLYKKASTPWEWHKPLFELAESLGLVAFSSPFDLSAVAFLESIDVPLYKIASF 129
Query: 660 DSNNLLFLKYAASKKLPLIISTGMVDKSAV-KTIYDIISSEHKQFCLLHXISAYPVPFED 836
+ ++ ++ A P+I+STGM + + + + I + LL S YP ED
Sbjct: 130 EMTDIPLIQAVARTGKPIIMSTGMASEEEIAEAVATIRAIGDNPLTLLKCTSTYPSKIED 189
Query: 837 CNLTVLQD 860
NL + D
Sbjct: 190 SNLVTMAD 197
>UniRef50_A1WSD6 Cluster: N-acylneuraminate-9-phosphate synthase;
n=1; Verminephrobacter eiseniae EF01-2|Rep:
N-acylneuraminate-9-phosphate synthase -
Verminephrobacter eiseniae (strain EF01-2)
Length = 352
Score = 77.0 bits (181), Expect = 1e-12
Identities = 49/185 (26%), Positives = 85/185 (45%), Gaps = 3/185 (1%)
Frame = +3
Query: 309 CFIIAEVGQNHQGDIGIAKQLIKAAKDAGASCVKFQKTCLKEKFTKKYLERSYDNHNSWG 488
C +I E+G NH + +LI AG +K Q+ +++ + Y G
Sbjct: 16 CIVIGEIGVNHNRQQDMLFRLIDEGIAAGLDVIKLQRFKAEQEIAMQAPAADYQKRAGAG 75
Query: 489 KTYGDHKKHLEFSESQYRELFKYAHEIGILFTASAMDMVSFDFLVN-LKVPFIKIGSGDS 665
++ + LE ++ + F Y + G+ F +A D S DFL + L +KI S +
Sbjct: 76 ESQLQMARQLELPDAWLTQAFDYCRQRGVGFLCTAFDHGSVDFLADRLGCKTVKIPSPEV 135
Query: 666 NNLLFLKYAASKKLPLIISTGMVDKSAVKTIYDIISSE--HKQFCLLHXISAYPVPFEDC 839
+N L++ A + L++STG V D +++E ++ L+H +S YP P E
Sbjct: 136 SNKPLLQHMARRFDGLLLSTGASYLGEVANAIDWLAAEAGPRELALMHCLSEYPAPVEQA 195
Query: 840 NLTVL 854
NL +
Sbjct: 196 NLRAM 200
>UniRef50_UPI0000384B44 Cluster: COG2089: Sialic acid synthase; n=1;
Magnetospirillum magnetotacticum MS-1|Rep: COG2089:
Sialic acid synthase - Magnetospirillum magnetotacticum
MS-1
Length = 346
Score = 76.2 bits (179), Expect = 2e-12
Identities = 65/188 (34%), Positives = 86/188 (45%), Gaps = 7/188 (3%)
Frame = +3
Query: 312 FIIAEVGQNHQGDIGIAKQLIKAAKDAGASCVKFQKTCLKE---KFTKK--YLERSYDNH 476
FIIAE G NH GDI AK+LI A +A A VKFQ E +F K YLE + +
Sbjct: 14 FIIAEAGVNHDGDIQRAKRLIDVAAEAQADAVKFQTWRPGEITGRFAYKVNYLEATTEQA 73
Query: 477 NSWGKTYGDHKKHLEFSESQYRELFKYAHEIGILFTASAMDMVSFDFLV-NLKVPFIKIG 653
S Y + L +REL + GILF ++ S FLV L +P +KIG
Sbjct: 74 ES---RY-ELSCRLALPYPVFRELKSHCEARGILFLSTPDGFDSLAFLVGELDMPIVKIG 129
Query: 654 SGDSNNLLFLKYAASKKLPLIISTGMVDKSAV-KTIYDIISSEHKQFCLLHXISAYPVPF 830
S + + +L+ P I+STG+ V K + + LLH S YP P
Sbjct: 130 STEVTHPQYLEAIGRTGRPAILSTGLSTLGEVEKAVAALRRGGVGPLALLHCTSEYPAPD 189
Query: 831 EDCNLTVL 854
NL +
Sbjct: 190 SQMNLRAM 197
>UniRef50_A4U183 Cluster: N-acetylneuraminate synthase; n=1;
Magnetospirillum gryphiswaldense|Rep:
N-acetylneuraminate synthase - Magnetospirillum
gryphiswaldense
Length = 354
Score = 75.8 bits (178), Expect = 3e-12
Identities = 53/143 (37%), Positives = 72/143 (50%), Gaps = 2/143 (1%)
Frame = +3
Query: 315 IIAEVGQNHQGDIGIAKQLIKAAKDAGASCVKFQKTCLKEKFTKKYLERSYDNHNSWG-K 491
IIAE G NH G I A +LI AA AGA VKFQ + Y N G +
Sbjct: 5 IIAEAGVNHDGKIDQALRLIDAAAAAGADVVKFQTFKAAALASAVAGRAEYQIRNLGGTE 64
Query: 492 TYGDHKKHLEFSESQYRELFKYAHEIGILFTASAMDMVSFDFLVN-LKVPFIKIGSGDSN 668
+ D + LE SE + L + + GI F +S D +S +FL++ L + IK+GSG+
Sbjct: 65 SQLDMLRRLELSEDDHFRLRDHCRQAGIGFLSSPFDRLSLEFLIDRLGLDTIKLGSGELT 124
Query: 669 NLLFLKYAASKKLPLIISTGMVD 737
N L A + +I+STGM D
Sbjct: 125 NGPLLLQAGASGRNIILSTGMAD 147
>UniRef50_Q3B0R9 Cluster: N-acylneuraminate-9-phosphate synthase;
n=1; Synechococcus sp. CC9902|Rep:
N-acylneuraminate-9-phosphate synthase - Synechococcus
sp. (strain CC9902)
Length = 349
Score = 74.1 bits (174), Expect = 9e-12
Identities = 58/196 (29%), Positives = 87/196 (44%), Gaps = 7/196 (3%)
Frame = +3
Query: 300 NNPCFIIAEVGQNHQGDIGIAKQLIKAAKDAGASCVKFQK---TCLKEKFTKKYLERSYD 470
+NP + IA++G NH + AK LIK A ++GA KFQ + K L S
Sbjct: 7 DNPLYFIADIGANHDSSLKRAKALIKTAAESGADAAKFQNFFAHSIVSDLGFKQLPNSIL 66
Query: 471 NHNS-WGKTYGDHKKHLEFSESQYRELFKYAHEIGILFTASAMDMVSFDFLVNLKVPFIK 647
+H + W ++ D S EL Y E GI + + D+ +FL N V K
Sbjct: 67 SHQAEWTESVFDVYDKASLSLEWTEELHSYCKECGISYMTTPYDISILEFL-NQYVACWK 125
Query: 648 IGSGDSNNLLFLKYAASKKLPLIISTGMVDKSAVKTIYDIISSEHKQFCLLHXISAYP-- 821
IGSGD L + + P+ I+TG + + V + + K+ L+ + Y
Sbjct: 126 IGSGDITWLDLISKVSQLGKPIAIATGASNFTEVCQAVNTVLQHTKKIILMQCNTNYTGC 185
Query: 822 -VPFEDCNLTVLQDYK 866
F+ NL+VL YK
Sbjct: 186 LSNFDYLNLSVLTTYK 201
>UniRef50_Q0P8U0 Cluster: Pse synthetase; n=14; Campylobacter|Rep:
Pse synthetase - Campylobacter jejuni
Length = 343
Score = 74.1 bits (174), Expect = 9e-12
Identities = 59/185 (31%), Positives = 87/185 (47%), Gaps = 7/185 (3%)
Frame = +3
Query: 312 FIIAEVGQNHQGDIGIAKQLIKAAKDAGASCVKFQKTCLKEKFTKKYLERSYDNHNSWGK 491
FIIAE+ NH G + +A + IKAAK AGA +K Q T + T L ++ G
Sbjct: 13 FIIAELSANHAGSLEMALKSIKAAKKAGADAIKIQ-TYTPDSLT---LNSDKEDFIIKGG 68
Query: 492 TYGDHKKHLEFSESQ------YRELFKYAHEIGILFTASAMDMVSFDFLVNLKVPFIKIG 653
+ D +K E ES + ++F+ A GIL +S +FL KI
Sbjct: 69 LW-DKRKLYELYESAKTPYEWHSQIFETAQNEGILCFSSPFAKEDVEFLKRFDPIAYKIA 127
Query: 654 SGDSNNLLFLKYAASKKLPLIISTGMVDKSAVKTIYDIISSE-HKQFCLLHXISAYPVPF 830
S ++N+ F++ A +K P I+STG+ + + I +I E + L S YP
Sbjct: 128 SFEANDENFVRLIAKEKKPTIVSTGIATEEELFKICEIFKEEKNPDLVFLKCTSTYPTAI 187
Query: 831 EDCNL 845
ED NL
Sbjct: 188 EDMNL 192
>UniRef50_A2BSE7 Cluster: Sialic acid synthase; n=1; Prochlorococcus
marinus str. AS9601|Rep: Sialic acid synthase -
Prochlorococcus marinus (strain AS9601)
Length = 356
Score = 74.1 bits (174), Expect = 9e-12
Identities = 53/188 (28%), Positives = 88/188 (46%), Gaps = 4/188 (2%)
Frame = +3
Query: 315 IIAEVGQNHQGDIGIAKQLIKAAKDAGASCVKFQ---KTCLKEKFTKKYLERSYDNHNSW 485
IIAE+G NH GDI A +I K+ G VKFQ + K +K Y + + + S
Sbjct: 23 IIAEIGVNHGGDIDKAIAMIDDVKNNGGDAVKFQTYKANLIARKDSKAYWDTTKEKTMSQ 82
Query: 486 GKTYGDHKKHLEFSESQYRELFKYAHEIGILFTASAMDMVSFDFLVNLKVPFIKIGSGDS 665
+ + + K F +++++ Y +LF ++ D S ++ +N K+ S D
Sbjct: 83 FELFSKYDK---FGLEEFKKIEDYCKRKSVLFMSTPFDSYSANY-INQLSKIHKVASVDI 138
Query: 666 NNLLFLKYAASKKLPLIISTGMVDKSAVKTIYDIISSEHK-QFCLLHXISAYPVPFEDCN 842
N + + AS +I+STG + +K +I S+ K LLH + YP +D N
Sbjct: 139 TNHILISQLASYGKDIILSTGASNLDEIKAAVSLIESKSKISPALLHCVVNYPTLDKDAN 198
Query: 843 LTVLQDYK 866
L ++ K
Sbjct: 199 LLRIKKLK 206
>UniRef50_Q726U8 Cluster: NeuB family protein; n=2; Desulfovibrio
vulgaris subsp. vulgaris|Rep: NeuB family protein -
Desulfovibrio vulgaris (strain Hildenborough / ATCC
29579 / NCIMB8303)
Length = 358
Score = 73.3 bits (172), Expect = 2e-11
Identities = 57/178 (32%), Positives = 81/178 (45%), Gaps = 1/178 (0%)
Frame = +3
Query: 315 IIAEVGQNHQGDIGIAKQLIKAAKDAGASCVKFQKTCLKEKFTKKYLERSYDNHNSWGKT 494
IIAEVG NH GD +A ++I++A + GA VK Q F L H S
Sbjct: 24 IIAEVGLNHGGDADLAWEMIESAWEHGADLVKLQS------FAPGGLL-----HPSL--P 70
Query: 495 YGDHKKHLEFSESQYRELFKYAHEIGILFTASAMDMVSFDFLVNLKVPFIKIGSGDSNNL 674
Y + + S Q+ LF+ A GI + D + D ++ +K+ S D +N
Sbjct: 71 YAASMEGMMLSLRQHEALFERARRQGIALITTPFDAPTLDLCTRFRIAAVKVASMDLDNT 130
Query: 675 LFLKYAASKKLPLIISTGMVDKSAV-KTIYDIISSEHKQFCLLHXISAYPVPFEDCNL 845
L+ A LP+I+S GM D + + K + + S LLH IS YP ED L
Sbjct: 131 AHLRAVARTGLPVILSCGMGDHADIGKALATLRESGATDVTLLHCISDYPARLEDMQL 188
>UniRef50_A4U173 Cluster: NeuB; n=1; Magnetospirillum
gryphiswaldense|Rep: NeuB - Magnetospirillum
gryphiswaldense
Length = 337
Score = 73.3 bits (172), Expect = 2e-11
Identities = 47/183 (25%), Positives = 86/183 (46%), Gaps = 2/183 (1%)
Frame = +3
Query: 315 IIAEVGQNHQGDIGIAKQLIKAAKDAGASCVKFQKTCLKEKFTKKYLERSYDNHNSWGKT 494
+IAE+G + D+ + K+++++A G VKFQ + T SY + +
Sbjct: 13 VIAEIGAKY-ADMPVLKEMVRSAVACGVDMVKFQTFQARTIATPG----SYFTFDDGSRV 67
Query: 495 -YGDHKKHLEFSESQYRELFKYAHEIGILFTASAMDMVSFDFLVNLKVPFIKIGSGDSNN 671
+ + E + + EL E+G+ + ++ + D L K GS D N
Sbjct: 68 PQSEWFQKYELTRDDHVELIDLCRELGVAWMSTPSHVSDLDLLEPFDPIAYKTGSDDLTN 127
Query: 672 LLFLKYAASKKLPLIISTGMVDKSAVKTIYDIIS-SEHKQFCLLHXISAYPVPFEDCNLT 848
FL+ A K P+++STGM + ++ D+I+ + + + LLH + +YP ED NL
Sbjct: 128 TRFLRQIAEKGRPMVVSTGMCTLAEIERAVDVITRTGNTELILLHCVVSYPAKAEDANLR 187
Query: 849 VLQ 857
++
Sbjct: 188 AIE 190
>UniRef50_A4BEM9 Cluster: Sialic acid synthase; n=1; Reinekea sp.
MED297|Rep: Sialic acid synthase - Reinekea sp. MED297
Length = 354
Score = 72.5 bits (170), Expect = 3e-11
Identities = 50/144 (34%), Positives = 72/144 (50%)
Frame = +3
Query: 300 NNPCFIIAEVGQNHQGDIGIAKQLIKAAKDAGASCVKFQKTCLKEKFTKKYLERSYDNHN 479
N+ F+IAE G NH GD+ +AK+LI+ A AGA +KFQ T + E ++
Sbjct: 3 NDSVFLIAEAGVNHNGDVELAKELIELAAAAGADAIKFQ-TFIPEALVTTTARKAGYQKT 61
Query: 480 SWGKTYGDHKKHLEFSESQYRELFKYAHEIGILFTASAMDMVSFDFLVNLKVPFIKIGSG 659
+ ++ + L + EL YA I F ++A + S L L V KI SG
Sbjct: 62 AHEESQLAMLQALALPLPVFDELKAYADSKAIEFMSTAFESESLALLSQLAVRRYKIPSG 121
Query: 660 DSNNLLFLKYAASKKLPLIISTGM 731
+ NL FL A+ + LI+STGM
Sbjct: 122 ELTNLPFLIEHAALQQDLILSTGM 145
>UniRef50_Q2BI17 Cluster: N-acetylneuraminate synthase; n=4;
Bacteria|Rep: N-acetylneuraminate synthase -
Neptuniibacter caesariensis
Length = 363
Score = 72.1 bits (169), Expect = 3e-11
Identities = 56/211 (26%), Positives = 92/211 (43%), Gaps = 6/211 (2%)
Frame = +3
Query: 273 ITEDVKVGGNNPCFIIAEVGQNHQGDIGIAKQLIKAAKDAGASCVKFQ---KTCLKEKFT 443
I + ++P + IA++ NH GD+ AK+LI + +AGA KFQ + F
Sbjct: 11 IVNSHSISESDPTYFIADIAANHDGDLEKAKELIWLSAEAGADAAKFQHFKADTIVSDFG 70
Query: 444 KKYLERSYDNHNSWGKTYGDHKKHLEFSESQYRELFKYAHEIGILFTASAMDMVSFDFLV 623
K L + ++W K+ + E + EL + I F S D D+ +
Sbjct: 71 FKSLGGQQSHQSTWEKSVYEVYADAEVDLNWTEELVNTCKQAEIDFFTSPYDFDLADY-I 129
Query: 624 NLKVPFIKIGSGDSNNLLFLKYAASKKLPLIISTGMVDKSAVKTIYDIISSEHKQFCLLH 803
+ VP KIGSGD L++ A K P ++TG + + V + + + L+
Sbjct: 130 DQFVPAHKIGSGDITWHAMLEHIAKKNKPYFLATGASELADVVAAVEACLKINPKLVLMQ 189
Query: 804 XISAYPVPFED---CNLTVLQDYKILLMYLL 887
+ Y E+ NL VL+ Y+ L L+
Sbjct: 190 CNTNYTASLENFAYINLNVLKTYRTLFPELV 220
>UniRef50_Q11RF6 Cluster: N-acetylneuraminic acid synthetase; n=2;
Flexibacteraceae|Rep: N-acetylneuraminic acid synthetase
- Cytophaga hutchinsonii (strain ATCC 33406 / NCIMB
9469)
Length = 348
Score = 68.5 bits (160), Expect = 4e-10
Identities = 52/189 (27%), Positives = 89/189 (47%), Gaps = 4/189 (2%)
Frame = +3
Query: 291 VGGNNPCFIIAEVGQNHQGDIGIAKQLIKAAKDAGASCVKFQK-TCLKEKFTKKYLERSY 467
+ N+ F+IAE+ NH + A ++ AA AGA +K Q T F E
Sbjct: 9 ISENHKPFVIAEMSGNHNQSLDRALAIVDAAAAAGAHALKLQTYTADTITFNGTSDEFII 68
Query: 468 DNHNSWGKTYGDHKKHLE-FSESQYRE-LFKYAHEIGILFTASAMDMVSFDFLVNLKVPF 641
+ NS K H+ + + ++ ++ +F+ A G++ +S D + DFL +L VP
Sbjct: 69 KDENSIWKNQNLHQLYQQAYTPWEWHAPIFERAKSHGMIAFSSPFDTTAVDFLESLDVPC 128
Query: 642 IKIGSGDSNNLLFLKYAASKKLPLIISTGMVDKSAVKTIYDIISSEH-KQFCLLHXISAY 818
KI S ++ + + LK A P+I+STG+ + ++ ++ K+ LL S Y
Sbjct: 129 YKIASFENTDHILLKKVAQTNKPVIMSTGVSTIADIQESVKVLRDNGCKELVLLKCTSTY 188
Query: 819 PVPFEDCNL 845
P E N+
Sbjct: 189 PATPESTNI 197
>UniRef50_Q0YTS4 Cluster: N-acylneuraminate-9-phosphate synthase;
n=5; Bacteria|Rep: N-acylneuraminate-9-phosphate
synthase - Chlorobium ferrooxidans DSM 13031
Length = 354
Score = 68.5 bits (160), Expect = 4e-10
Identities = 49/197 (24%), Positives = 87/197 (44%), Gaps = 7/197 (3%)
Frame = +3
Query: 291 VGGNNPCFIIAEVGQNHQGDIGIAKQLIKAAKDAGASCVKFQKTCLKEKFTKKYLERSYD 470
+G +P FI+AE+ NH G + A +++ AAK +GA +K Q T + T + +
Sbjct: 15 LGPGHPAFIVAEMSGNHGGSLEYALEIVHAAKRSGADAIKLQ-TYTADTITLNSDRQDFC 73
Query: 471 NHNSWGKTYGDHKKHLEFSESQY------RELFKYAHEIGILFTASAMDMVSFDFLVNLK 632
+ G + DH Y +F+ A + + +S D + + L L
Sbjct: 74 IPS--GTPWADHSTLWSLYNKAYTPWDWHESIFREARSLDLEIFSSPFDESAVELLEQLG 131
Query: 633 VPFIKIGSGDSNNLLFLKYAASKKLPLIISTGMVDKSAVK-TIYDIISSEHKQFCLLHXI 809
KI S + ++ L A P+I+STG+ ++ + + ++ + LL
Sbjct: 132 ASAYKIASPEITHIPLLDKVARTGKPVILSTGLAALEDIELALATLRAAGSGEIILLKCT 191
Query: 810 SAYPVPFEDCNLTVLQD 860
+AYP P E+ NL + D
Sbjct: 192 TAYPAPIEEANLRTISD 208
>UniRef50_Q2IZW6 Cluster: N-acetylneuraminate synthase; n=1;
Rhodopseudomonas palustris HaA2|Rep: N-acetylneuraminate
synthase - Rhodopseudomonas palustris (strain HaA2)
Length = 332
Score = 68.1 bits (159), Expect = 6e-10
Identities = 52/185 (28%), Positives = 81/185 (43%)
Frame = +3
Query: 300 NNPCFIIAEVGQNHQGDIGIAKQLIKAAKDAGASCVKFQKTCLKEKFTKKYLERSYDNHN 479
+NP +IIAE+G H G G A +L++ A + GA VKFQ + + SY +
Sbjct: 5 SNP-YIIAEIGSVHDGSFGNACRLLETAAECGADAVKFQTHIAEAETLPNAPSPSYFS-- 61
Query: 480 SWGKTYGDHKKHLEFSESQYRELFKYAHEIGILFTASAMDMVSFDFLVNLKVPFIKIGSG 659
+ + K FS Q+R L A + F +S + + D L ++ V KI SG
Sbjct: 62 --AEPRTAYFKRTGFSPEQWRALAALAKSTKVDFLSSPFSLEAVDLLEDVGVAAYKIPSG 119
Query: 660 DSNNLLFLKYAASKKLPLIISTGMVDKSAVKTIYDIISSEHKQFCLLHXISAYPVPFEDC 839
+ +N+ L A P+ +S+GM + + + LL S YP P E
Sbjct: 120 EVSNIPLLSRIAQTGKPVFLSSGMSNWEELDAAVGALRG--SALTLLQCTSKYPCPPEQV 177
Query: 840 NLTVL 854
L +
Sbjct: 178 GLNAM 182
>UniRef50_O83573 Cluster: Spore coat polysaccharide biosynthesis
protein; n=1; Treponema pallidum|Rep: Spore coat
polysaccharide biosynthesis protein - Treponema pallidum
Length = 378
Score = 67.3 bits (157), Expect = 1e-09
Identities = 57/182 (31%), Positives = 81/182 (44%), Gaps = 3/182 (1%)
Frame = +3
Query: 318 IAEVGQNHQGDIGIAKQLIKAAKDAGASCVKFQKTCLKEKFTKKYLERSYDNHNSWGKTY 497
IAE+G H G A+ LI AA DA A+ VKFQ E L + + Y
Sbjct: 18 IAEIGSAHAGSFDRARALIDAAADAAAAAVKFQLIYAHEILHP--LTGAVRLPSGAVSLY 75
Query: 498 GDHKKHLEFSESQYRELFKYAHEIGILFTASAMDMVSFDFLVNLKVPFIKIGSGDSNNLL 677
+ LE S Y + F +A G+L S S + LK F+K+ S + N
Sbjct: 76 -QRFEELEVPLSFYAQCFNHARSRGMLVGISPFGPRSATEALALKPDFLKVASPELNYPT 134
Query: 678 FLKYAASKKLPLIISTGMVDKSAVKTIYDIISSEHKQ---FCLLHXISAYPVPFEDCNLT 848
+ A+ +LPLI+S+G+ ++ KQ LLH I+AYP P + NL
Sbjct: 135 LISTLAAAELPLILSSGVCLLKEIEGALAQCRQYTKQGSSHALLHCITAYPAPETEYNLA 194
Query: 849 VL 854
+L
Sbjct: 195 LL 196
>UniRef50_Q0AN71 Cluster: N-acetylneuraminate synthase; n=1;
Maricaulis maris MCS10|Rep: N-acetylneuraminate synthase
- Maricaulis maris (strain MCS10)
Length = 305
Score = 65.7 bits (153), Expect = 3e-09
Identities = 50/181 (27%), Positives = 85/181 (46%), Gaps = 1/181 (0%)
Frame = +3
Query: 315 IIAEVGQNHQGDIGIAKQLIKAAKDAGASCVKFQKTCLKEKFTKKYLERSYDNHNSWGKT 494
+IAE+G NH GD+ AK+ I+A+ AGA VKFQ T +E +++ + D +
Sbjct: 6 VIAEIGSNHGGDLDQAKRYIEASAKAGADVVKFQ-TLTREGLIARFV-KGADGTVTENPK 63
Query: 495 YGDHKKHLEFSESQYRELFKYAHEIGILFTASAMDMVSFDFLVNLKVPFIKIGSGDSNNL 674
+ + + + L A + G+ F ++ + + + + +L V KI SGD
Sbjct: 64 FAAF-GNAGLPDDWHAPLMTCAADNGVEFMSTPFSLDAVELMESLGVKRYKIASGDLTFT 122
Query: 675 LFLKYAASKKLPLIISTGMVDKSAVKT-IYDIISSEHKQFCLLHXISAYPVPFEDCNLTV 851
L+ + LI+STG V T + + S LH ++YP +ED NL+
Sbjct: 123 PLLEALGATGKRLILSTGASYLDEVTTAVTTLTRSGCPHLTALHCAASYPPAWEDLNLSA 182
Query: 852 L 854
+
Sbjct: 183 I 183
>UniRef50_Q8EC83 Cluster: Polysaccharide biosynthesis
related-protein; n=6; Proteobacteria|Rep: Polysaccharide
biosynthesis related-protein - Shewanella oneidensis
Length = 290
Score = 65.3 bits (152), Expect = 4e-09
Identities = 60/196 (30%), Positives = 91/196 (46%), Gaps = 7/196 (3%)
Frame = +3
Query: 300 NNPCFIIAEVGQNHQGDIGIAKQLIKAAKDAGASCVKFQKTCLKEKFTKKYLERSYDNHN 479
++P FI AEV NH D+ + IK A + G VKFQ ++E F + L +S + H
Sbjct: 4 HSPLFI-AEVSSNHHRDLQRCIEFIKTAAEIGCDAVKFQLFKIEELFAPEILSKS-EMHR 61
Query: 480 SWGKTYGDHKKHLEFSESQYRELFKYAHEIGILFTASAMDMVSFDFLVNLKVPFIKIGSG 659
+K E S +L + E GI F+ + + D + L+ PF+
Sbjct: 62 K--------RKEWELPVSFLPQLKQSCDEYGIQFSCTPFYL---DAVAELE-PFVDFYKI 109
Query: 660 DSNNLLF---LKYAASKKLPLIISTGMVD----KSAVKTIYDIISSEHKQFCLLHXISAY 818
S LL+ L P++IS GM A+KT+ + +S+ LLH +SAY
Sbjct: 110 ASYELLWDDLLAACVKTGKPVVISAGMATIEEIDHALKTLKENGASD---ITLLHCVSAY 166
Query: 819 PVPFEDCNLTVLQDYK 866
P P +CNL VL ++
Sbjct: 167 PTPEHECNLAVLGSFR 182
>UniRef50_A0LAB4 Cluster: N-acetylneuraminic acid synthase,
N-terminal domain; n=2; Proteobacteria|Rep:
N-acetylneuraminic acid synthase, N-terminal domain -
Magnetococcus sp. (strain MC-1)
Length = 500
Score = 64.1 bits (149), Expect = 9e-09
Identities = 53/187 (28%), Positives = 82/187 (43%), Gaps = 6/187 (3%)
Frame = +3
Query: 312 FIIAEVGQN----HQG-DIGIAKQLIKAAKDAGASCVKFQKTCLKEKFTKKYLERSYDNH 476
+IIAE G N H D+ + K LI AA +GA VKFQ ++ + + +Y
Sbjct: 161 YIIAEAGSNWRMGHPARDLAMGKALIDAAVVSGADAVKFQTYRPEKVYVANAGQSNYLAE 220
Query: 477 NSWGKTYGDHKKHLEFSESQYRELFKYAHEIGILFTASAMDMVSFDFLVNLKVPFIKIGS 656
+ + D L S +L Y + GI F ++ + F ++ VP KI S
Sbjct: 221 SGIKQDIRDIFADLAMPYSMIEDLAGYCKKAGIQFLSTGFSVEDFQ-AIDPWVPLHKIAS 279
Query: 657 GDSNNLLFLKYAASKKLPLIISTGMVDKSAVKTIYDIISSE-HKQFCLLHXISAYPVPFE 833
+ ++L L AA+ PL++STG + + S+ + CLL + YP P
Sbjct: 280 YEISHLRLLDLAANSGKPLLLSTGASRAEDIAWAVERYHSQGGRDLCLLQCTAKYPAPLA 339
Query: 834 DCNLTVL 854
N VL
Sbjct: 340 TVNSAVL 346
>UniRef50_A7DQU2 Cluster: N-acylneuraminate-9-phosphate synthase;
n=1; Candidatus Nitrosopumilus maritimus SCM1|Rep:
N-acylneuraminate-9-phosphate synthase - Candidatus
Nitrosopumilus maritimus SCM1
Length = 351
Score = 62.1 bits (144), Expect = 4e-08
Identities = 54/196 (27%), Positives = 84/196 (42%), Gaps = 10/196 (5%)
Frame = +3
Query: 312 FIIAEVGQN-----HQGDIGIAKQLIKAAKDAGASCVKFQKTCLKEKFTKKYLERSYDNH 476
F+IAE G N + D+ AK+LI+ A AGA VKFQ + + Y
Sbjct: 14 FVIAEAGSNWKCGDYSDDLEQAKKLIETAAKAGADAVKFQTYKPETIYVSDAGNSDYLEK 73
Query: 477 NSWGKTYGDHKKHLEFSESQYRELFKYAHEIGILFTASAMDMVSFDFLVNLKVPFIKIGS 656
+ + +HL EL KY E I F ++ V V+ K+ S
Sbjct: 74 YGIKENINEIFEHLSMPYEMIPELKKYCDEKNIQFMSTPFS-VQDAKEVDKFTEIHKVAS 132
Query: 657 GDSNNLLFLKYAASKKLPLIISTGMVDKSAVKTIYDII-SSEHKQFCLLHXISAYPVPFE 833
+ N++ L++ A + P+I+STG + ++I + + L+ S YP P +
Sbjct: 133 FEINHIRLLEFLAKTQKPIIVSTGASTFKEIDFAINLIRKNGNDNIALMQCTSKYPCPID 192
Query: 834 DCNL----TVLQDYKI 869
NL T+ Q YKI
Sbjct: 193 SLNLKTISTMGQKYKI 208
>UniRef50_Q2BJD7 Cluster: N-acetylneuraminic acid synthetase; n=1;
Neptuniibacter caesariensis|Rep: N-acetylneuraminic acid
synthetase - Neptuniibacter caesariensis
Length = 270
Score = 61.3 bits (142), Expect = 7e-08
Identities = 51/197 (25%), Positives = 90/197 (45%), Gaps = 3/197 (1%)
Frame = +3
Query: 318 IAEVGQNHQGDIGIAKQLIKAAKDAGASCVKFQKTCLKEKFTKKYLERSYDNHNSWGKTY 497
IAE+G N GD+ +A+ +I AA +GA+ KFQ +K ++DN G+
Sbjct: 4 IAEIGWNFMGDMKLAEDMIAAAAQSGATTAKFQYW-----NPEKLKAGAWDND---GRRE 55
Query: 498 GDHKKHLEFSESQYRELFKYAHEIGILFTASAMDMVSFDFLVNLKVPFIKIGSGDSNNLL 677
+K L + Q +L + + + F S + +F+ IKI S + N+
Sbjct: 56 IYNKACLNADKIQ--QLTELCSKHNVKFLLSVFNKEDAEFVSQFSTEAIKIPSHEVANIE 113
Query: 678 FLKYAASKKLPLIISTGMVDKSAVKTIYDI---ISSEHKQFCLLHXISAYPVPFEDCNLT 848
++YA S + +S G + +K + ++ I S + +H +S+YP P E NL
Sbjct: 114 LIRYALSTYKRVFLSLGACTEEELKDVSELVGSIRSNGEDVVAMHCVSSYPCPVEKVNLP 173
Query: 849 VLQDYKILLMYLLXIRD 899
+ + + L L + D
Sbjct: 174 RMAELQKLFNGELGLSD 190
>UniRef50_Q319P5 Cluster: Putative spore coat polysaccharide
biosynthesis protein E; n=1; Prochlorococcus marinus
str. MIT 9312|Rep: Putative spore coat polysaccharide
biosynthesis protein E - Prochlorococcus marinus (strain
MIT 9312)
Length = 521
Score = 51.2 bits (117), Expect = 7e-05
Identities = 41/192 (21%), Positives = 75/192 (39%), Gaps = 3/192 (1%)
Frame = +3
Query: 300 NNPCFIIAEVGQNHQGDIGIAKQLIKAAKDAGASCVKFQKTCLKEKFTK--KYLERSYDN 473
N+ II E+ NHQG + K ++ A + + +K +F +++ S D
Sbjct: 13 NHKIRIIFEIANNHQGSVDHFKNILDDIFSASKTFADKFEFLIKFQFRDLPTFIDESIDP 72
Query: 474 HNSWGKTYGDHKKHLEFSESQYRELFKYAHEIGILFTASAMDMVSFDFLVNLKVPFIKIG 653
+ + K + Q+ ++ + G + D S + + KI
Sbjct: 73 SQN---KHISRFKETALLDEQWLQILNMVRDKGFKTIVTPFDEASVNKAERFGIEEYKIA 129
Query: 654 SGDSNNLLFLKYAASKKLPLIISTGMVDKSAVKTIYDIISSEHK-QFCLLHXISAYPVPF 830
S L+ A++ P+ ISTG + V IY + +F ++H YP P
Sbjct: 130 SCSCTEWSLLREVANQNKPVTISTGGRNLKEVDDIYSYFAHRIPYKFTIMHCCGIYPAPI 189
Query: 831 EDCNLTVLQDYK 866
+D NL + +K
Sbjct: 190 KDLNLNTINIFK 201
>UniRef50_UPI0000E87B4B Cluster: putative N-acetyl neuramic acid
synthetase NeuB; n=1; Methylophilales bacterium
HTCC2181|Rep: putative N-acetyl neuramic acid synthetase
NeuB - Methylophilales bacterium HTCC2181
Length = 615
Score = 50.8 bits (116), Expect = 9e-05
Identities = 56/195 (28%), Positives = 83/195 (42%), Gaps = 10/195 (5%)
Frame = +3
Query: 300 NNPCFIIAEVGQNHQGDIGIAKQLIKAAKDAGASCVKFQKTCLKEKFTKKYLERSYDNHN 479
+ P FIIAE+G NH GD IA +LIKAA A + +KFQ R+ DN
Sbjct: 7 SKPIFIIAEIGINHGGDFSIALELIKAAAQAKVNGIKFQ-------------YRNLDNAY 53
Query: 480 SWG-KTYGDHKKHLEFSESQYR-----ELFKYAH----EIGILFTASAMDMVSFDFLVNL 629
+ G K GD E +++ L AH E GI F A D+ F ++
Sbjct: 54 ADGAKQIGDEMLLKEITKNYLSPEVILRLVDDAHSLDIEAGISFFDEA-DIADFGDGIH- 111
Query: 630 KVPFIKIGSGDSNNLLFLKYAASKKLPLIISTGMVDKSAVKTIYDIISSEHKQFCLLHXI 809
F K S + NN + P+ +S G + + + ++ + + LH +
Sbjct: 112 HFDFFKSPSVELNNAPLINKMLGFDKPVYVSLGCHHEDQIDDAF--MALDKNNWIALHCV 169
Query: 810 SAYPVPFEDCNLTVL 854
S YPV + +L L
Sbjct: 170 SNYPVSLSNAHLGYL 184
>UniRef50_Q0IDQ4 Cluster: NeuB family protein; n=1; Synechococcus
sp. CC9311|Rep: NeuB family protein - Synechococcus sp.
(strain CC9311)
Length = 353
Score = 50.8 bits (116), Expect = 9e-05
Identities = 55/215 (25%), Positives = 91/215 (42%), Gaps = 7/215 (3%)
Frame = +3
Query: 252 LNMLEVKITEDVKVGGNNPCFIIAEVGQNHQGDIGIAKQLIKAAKDAGASCVKFQKTCLK 431
+++ ++ I V G+ P I+ ++ GD+ IA+ LI++ +G +K T +
Sbjct: 1 MSLRDICIGTQVLGEGHLP-IILPDIDMFFNGDLEIARGLIESVSKSGLRTIK---TAIL 56
Query: 432 EK----FTKKYLERSYDNHNSWGKT-YGDHKKHLEFSESQYRELFKYAHEIGILFTASAM 596
E F ER S+ Y + + Q+RELF G+ F S
Sbjct: 57 EDPMVVFDTPAEERYLCRDGSYKSVNYRSLIQKKVMTLDQHRELFNLIKSYGLNFIVSVY 116
Query: 597 DMVSFDFLVNLKVPFIKIGSGDSNNLLFLKYAASKKLPLIISTGMVDKSAVKTIYDIISS 776
+ S DF V+ IKI S + N L ++ +A LPL+I TG + S
Sbjct: 117 TLESVDFAVSEGAIAIKIASSNINFLPLIEKSARTGLPLLIDTGKSTLCEIFEARHAAYS 176
Query: 777 EHKQFCLL--HXISAYPVPFEDCNLTVLQDYKILL 875
++ L+ H +A P P E +L+ + LL
Sbjct: 177 ANQDVKLIFEHSPAAPPAPIERQDLSFMNYLSNLL 211
>UniRef50_Q2AHF7 Cluster: Antifreeze-like; n=1; Halothermothrix
orenii H 168|Rep: Antifreeze-like - Halothermothrix
orenii H 168
Length = 350
Score = 49.6 bits (113), Expect = 2e-04
Identities = 46/190 (24%), Positives = 79/190 (41%), Gaps = 3/190 (1%)
Frame = +3
Query: 312 FIIAEVGQNHQGDIGIAKQLIKAAKDAGASCVKFQKTCLKEKFTKKYLERSYDNHNSWGK 491
+II E NHQGDI K++I + G VKF E YL+ + H K
Sbjct: 4 YIIGETAYNHQGDIHYLKRMIDDIAEIGLQAVKFHLLLNPE----SYLQ---NKHPLIKK 56
Query: 492 TYGDHKKHLEFSESQYRELFKYAHEIGILFTASAMDMVSFDFL--VNLKVPFIKIGSGDS 665
K F+E ++ E+ Y+ + G+ A D+ S F+ + + I+I +
Sbjct: 57 I-----KEWIFTEKEWDEIINYSKQKGLDMIALCDDLDSLKFIKKYHRDLKGIEIHASSL 111
Query: 666 NNLLFLKYAASKKLPLIISTGMVDKSAVKTIYDIISSEHKQ-FCLLHXISAYPVPFEDCN 842
N+ L+ A +I+ G ++ + + K+ L++ +YP + N
Sbjct: 112 NDYFLLEEARDFPNSVILGIGGSTLDEIEYAVNFLKQRGKEDIILMYGFQSYPTDYTQIN 171
Query: 843 LTVLQDYKIL 872
L +Q K L
Sbjct: 172 LAKMQKLKNL 181
>UniRef50_A5W0I0 Cluster: N-acetylneuraminic acid synthase,
N-terminal domain; n=1; Pseudomonas putida F1|Rep:
N-acetylneuraminic acid synthase, N-terminal domain -
Pseudomonas putida F1
Length = 369
Score = 48.8 bits (111), Expect = 4e-04
Identities = 40/183 (21%), Positives = 73/183 (39%), Gaps = 1/183 (0%)
Frame = +3
Query: 318 IAEVGQNHQGDIGIAKQLIKAAKDAGASC-VKFQKTCLKEKFTKKYLERSYDNHNSWGKT 494
+ E+ NH G + ++ +K +D G K +K +F D +
Sbjct: 17 VLELANNHWGKL---ERGLKIVRDHGTIARYNNVKAAIKLQFRDVDEFIHPDFKGTADLR 73
Query: 495 YGDHKKHLEFSESQYRELFKYAHEIGILFTASAMDMVSFDFLVNLKVPFIKIGSGDSNNL 674
Y + +++++ + + + + A+ D S D V +P IKI S D N+
Sbjct: 74 YVKKTEDTRLTKAEFARMVEEVRNLSCIPMATPFDEASVDLCVEFDMPIIKIASSDMNDW 133
Query: 675 LFLKYAASKKLPLIISTGMVDKSAVKTIYDIISSEHKQFCLLHXISAYPVPFEDCNLTVL 854
++ AS + P IISTG + + I + H +S YP ++ L +
Sbjct: 134 PLIEKIASTRRPTIISTGGASEKDLDDIVRYFEKRDIPLAINHCVSLYPSEDDELQLDQI 193
Query: 855 QDY 863
DY
Sbjct: 194 -DY 195
>UniRef50_A5IGD9 Cluster: Spore coat polysaccharide biosynthesis
protein E; n=5; Legionella pneumophila|Rep: Spore coat
polysaccharide biosynthesis protein E - Legionella
pneumophila (strain Corby)
Length = 368
Score = 44.8 bits (101), Expect = 0.006
Identities = 45/199 (22%), Positives = 82/199 (41%), Gaps = 10/199 (5%)
Frame = +3
Query: 291 VGGNNPCFIIAEVGQNHQGDIGIAKQLIKAAKDAGASCVKFQKTCLK-EKFTKKYLERSY 467
+G N+P +AE+G D+GIA+QL+ + +Q LK E +
Sbjct: 17 IGENHPPIFLAEIGTFFNQDLGIAEQLLHKIISI-RDKIPYQPLILKTEILNNPNICLPV 75
Query: 468 DNHNSWGKTYGDHKKH-----LE---FSESQYRELFKYAHEIGILFTASAMDMVSFDFLV 623
D ++ G+ +K +E Y LF + F S ++ + DF +
Sbjct: 76 DYEETYTSKSGEVRKENYRSLIERKVLPLEHYSMLFSLLKNANLPFIVSIYELDTIDFAI 135
Query: 624 NLKVPFIKIGSGDSNNLLFLKYAASKKLPLIISTGMVDKSAV-KTIYDIISSEHKQFCLL 800
+K S + ++ +++ A LPLII TG + + K + S+ ++ +
Sbjct: 136 KQGACALKTSSSNIVHIPLIRHLAKTGLPLIIDTGRSSLTDICKAVETAKSAGCEKIIIE 195
Query: 801 HXISAYPVPFEDCNLTVLQ 857
H +P E NL +L+
Sbjct: 196 HSPDGHPALPEAHNLRMLR 214
>UniRef50_Q7NR94 Cluster: Probable spore coat polysaccharide
biosynthesis protein E; n=1; Chromobacterium
violaceum|Rep: Probable spore coat polysaccharide
biosynthesis protein E - Chromobacterium violaceum
Length = 495
Score = 44.0 bits (99), Expect = 0.011
Identities = 42/186 (22%), Positives = 75/186 (40%), Gaps = 4/186 (2%)
Frame = +3
Query: 300 NNPCFIIAEVGQNHQGDIGIAKQLIKAAKDAGASCVKFQKTCLKEKFTKKYLERSYDNHN 479
+ P FI E+ NH G++ LI+A ++ SC F F +Y H+
Sbjct: 2 SKPLFIF-EMANNHMGNVEHGVALIRAIRE---SCQGFD---FDFGFKLQYRNLDTFIHS 54
Query: 480 SW-GKTYGDHKKHLEFSESQYRELFKYAHEI---GILFTASAMDMVSFDFLVNLKVPFIK 647
S+ G+ + K E + Q ++ K E+ G + D S D + + IK
Sbjct: 55 SFKGRDDVKYVKRFEETRLQPEQMQKLVAEMKANGFKAICTPFDEESVDLIEAHGIEIIK 114
Query: 648 IGSGDSNNLLFLKYAASKKLPLIISTGMVDKSAVKTIYDIISSEHKQFCLLHXISAYPVP 827
I S + L+ A P++ ST + + + + K ++H ++ YP P
Sbjct: 115 IASCSFTDWPLLERIARSDKPVVASTAGARREDIDKVVSFMLHRGKDLTIMHCVAEYPTP 174
Query: 828 FEDCNL 845
+ +L
Sbjct: 175 DDHLHL 180
>UniRef50_Q88Z00 Cluster: Non-ribosomal peptide synthetase NpsB;
n=1; Lactobacillus plantarum|Rep: Non-ribosomal peptide
synthetase NpsB - Lactobacillus plantarum
Length = 805
Score = 38.7 bits (86), Expect = 0.40
Identities = 25/77 (32%), Positives = 37/77 (48%), Gaps = 2/77 (2%)
Frame = +3
Query: 426 LKEKFTKK-YLERSYDNHNSWGKTYGDHKKHLEFSESQYRELFKYAHEI-GILFTASAMD 599
L EK T K + SY N N WG GD+ K L E +YR ++I G+ S +
Sbjct: 326 LNEKATNKAFTSVSYQNQNIWGYRTGDYAKVLPNGELEYRGRRDSQYKINGVRIDLSEVG 385
Query: 600 MVSFDFLVNLKVPFIKI 650
V + + NLK ++ +
Sbjct: 386 SVCREIIPNLKQCYLAV 402
>UniRef50_UPI0000F219ED Cluster: PREDICTED: hypothetical protein;
n=1; Danio rerio|Rep: PREDICTED: hypothetical protein -
Danio rerio
Length = 100
Score = 37.5 bits (83), Expect = 0.92
Identities = 15/36 (41%), Positives = 24/36 (66%)
Frame = +3
Query: 594 MDMVSFDFLVNLKVPFIKIGSGDSNNLLFLKYAASK 701
MD ++ +FL + VPF K+ S D+NN+ +L+ A K
Sbjct: 1 MDEMAVEFLHEINVPFFKVASADTNNIPYLEKTAKK 36
>UniRef50_A2ENS5 Cluster: Putative uncharacterized protein; n=1;
Trichomonas vaginalis G3|Rep: Putative uncharacterized
protein - Trichomonas vaginalis G3
Length = 1602
Score = 37.1 bits (82), Expect = 1.2
Identities = 21/56 (37%), Positives = 32/56 (57%)
Frame = +3
Query: 114 PYLFDLILKGRSINLLLRSDSLFPSDPA*TGTRFSFVCFYGTLVVVLNMLEVKITE 281
P+LF LI KG+ ++ +LR+ SLF S+ F F ++ VL+ L VK T+
Sbjct: 552 PFLFKLITKGKEVDEILRNLSLFVSE---NNIPFDISTFLTAILYVLSCLNVKSTD 604
>UniRef50_Q54FM7 Cluster: Putative uncharacterized protein; n=1;
Dictyostelium discoideum AX4|Rep: Putative
uncharacterized protein - Dictyostelium discoideum AX4
Length = 888
Score = 35.9 bits (79), Expect = 2.8
Identities = 35/154 (22%), Positives = 66/154 (42%), Gaps = 6/154 (3%)
Frame = +3
Query: 402 CVKFQKTCLKEKFTKKYLERSYDNHNSWGKTY-GDHKKHLEFSESQYRELFKYAHEIG-- 572
C +F K E F K ++Y N NS KT H + E ++ K+ +++
Sbjct: 379 CYRFNKDRCLESFLIKQFRKTYSNSNSNSKTVLFSHCNNKEKQIEFINQVIKFKNDLPNP 438
Query: 573 ILFTASAMDMVSFDFLVNLKVPFI---KIGSGDSNNLLFLKYAASKKLPLIISTGMVDKS 743
+LF + S + + ++ F + ++NNLL K + K+P II+ +
Sbjct: 439 LLFFYLVISFDSLELIKMVEKGFTDNNNNNNNNNNNLLEYKETYNNKIPFIITRYIRSIQ 498
Query: 744 AVKTIYDIISSEHKQFCLLHXISAYPVPFEDCNL 845
++ +++ HK + S+Y F + NL
Sbjct: 499 VMEYLFE----NHKNHFIQTSSSSYISFFINLNL 528
>UniRef50_UPI000038CA6C Cluster: COG5295: Autotransporter adhesin;
n=1; Nostoc punctiforme PCC 73102|Rep: COG5295:
Autotransporter adhesin - Nostoc punctiforme PCC 73102
Length = 829
Score = 35.5 bits (78), Expect = 3.7
Identities = 24/60 (40%), Positives = 33/60 (55%)
Frame = +3
Query: 234 GTLVVVLNMLEVKITEDVKVGGNNPCFIIAEVGQNHQGDIGIAKQLIKAAKDAGASCVKF 413
GT V+LN +V ITED GGNN + N Q D ++ +AKD+GAS ++F
Sbjct: 728 GTGNVILNANKVVITEDGTAGGNNWAL---DNDNNTQID---TSNIVGSAKDSGASTIQF 781
>UniRef50_UPI0000E117D8 Cluster: Na(+)-translocating NADH-quinone
reductase subunit A; n=1; alpha proteobacterium
HTCC2255|Rep: Na(+)-translocating NADH-quinone reductase
subunit A - alpha proteobacterium HTCC2255
Length = 68
Score = 35.1 bits (77), Expect = 4.9
Identities = 19/53 (35%), Positives = 32/53 (60%)
Frame = +1
Query: 412 SKRLASRRNSRKSI*SALMIITILGVKLMVITKNIWNFLKVNTVNYSNMLTRS 570
SK + N + ++ A ++IT+ VK+M +T+NI + L VN++N N L S
Sbjct: 13 SKTFYNNNNIQAAMCDAPLLITVAFVKMMGLTQNITSQLSVNSLNRVNNLKTS 65
>UniRef50_A5AVR4 Cluster: Putative uncharacterized protein; n=1;
Vitis vinifera|Rep: Putative uncharacterized protein -
Vitis vinifera (Grape)
Length = 441
Score = 34.7 bits (76), Expect = 6.5
Identities = 15/55 (27%), Positives = 29/55 (52%)
Frame = +3
Query: 318 IAEVGQNHQGDIGIAKQLIKAAKDAGASCVKFQKTCLKEKFTKKYLERSYDNHNS 482
+ E +H D+ + + L+ KD AS + + +T E F + ++ S+D HN+
Sbjct: 262 VLETPLSHMLDLNLCRPLLXICKDHHASSLSWVETLEIEDFCRDFIVMSFDQHNN 316
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 1,175,655,735
Number of Sequences: 1657284
Number of extensions: 21978564
Number of successful extensions: 47518
Number of sequences better than 10.0: 94
Number of HSP's better than 10.0 without gapping: 45412
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 47393
length of database: 575,637,011
effective HSP length: 104
effective length of database: 403,279,475
effective search space used: 162924907900
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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