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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= 030723E4_A04_e313_02.seq
         (1509 letters)

Database: human 
           237,096 sequences; 76,859,062 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

BC030016-1|AAH30016.1|  769|Homo sapiens gephyrin protein.            260   7e-69
AJ272343-1|CAC10537.1|  769|Homo sapiens gephyrin protein.            260   7e-69
AJ272033-1|CAC81240.1|  736|Homo sapiens gephyrin protein.            260   7e-69
AF272663-1|AAF81785.1|  736|Homo sapiens gephyrin protein.            260   7e-69
AB037806-1|BAA92623.1|  768|Homo sapiens KIAA1385 protein protein.    260   7e-69
BC117319-1|AAI17320.1|  257|Homo sapiens TPRXL protein protein.        41   0.010
AK092426-1|BAC03887.1|  258|Homo sapiens protein ( Homo sapiens ...    40   0.031
U78516-1|AAD03422.1| 1011|Homo sapiens cAMP-regulated guanine nu...    33   2.7  
BC040183-1|AAH40183.1|  867|Homo sapiens RAPGEF4 protein protein.      33   2.7  
AB209681-1|BAD92918.1|  643|Homo sapiens RAP guanine-nucleotide-...    33   2.7  
AB027471-1|BAB72179.1| 1011|Homo sapiens cAMP-GEFII protein.           33   2.7  
AB075513-1|BAE45759.1|  478|Homo sapiens putative protein produc...    33   3.6  

>BC030016-1|AAH30016.1|  769|Homo sapiens gephyrin protein.
          Length = 769

 Score =  260 bits (638), Expect = 7e-69
 Identities = 141/303 (46%), Positives = 187/303 (61%), Gaps = 1/303 (0%)
 Frame = +3

Query: 72   EAEDKQTELEVEILIAPQLGQDVRPVGFDIPMGTILVNKGEILDAAKIGVLAGAGYRSIT 251
            E++D   ELEV IL+  + GQD+RP+G DI  G  ++ KG  +  ++IG+LA  G   + 
Sbjct: 468  ESDDGTEELEVRILVQARPGQDIRPIGHDIKRGECVLAKGTHMGPSEIGLLATVGVTEVE 527

Query: 252  AQVNPKVALMSTGNELQEPSEVKLRPAHIRDSNRTMLKALLREHGYDSIDCGIARDTPEE 431
                P VA+MSTGNEL  P +  L P  IRDSNR+ L A ++EHGY +I+ GI  D P++
Sbjct: 528  VNKFPVVAVMSTGNELLNPED-DLLPGKIRDSNRSTLLATIQEHGYPTINLGIVGDNPDD 586

Query: 432  LVAGIATALSRADVLVCTGGVSMGERDLLKPVLLNDFGANLYYGRVRMKPGKPSTFATCQ 611
            L+  +   +SRADV++ +GGVSMGE+D LK VL  D  A +++GRV MKPG P+TFAT  
Sbjct: 587  LLNALNEGISRADVIITSGGVSMGEKDYLKQVLDIDLHAQIHFGRVFMKPGLPTTFATLD 646

Query: 612  FEGKTKYIFALPGNPVSAYVCCLLFVIRGLRVCNGREGAWPR-LRVRLSHAVALDPRPEY 788
             +G  K IFALPGNPVSA V C LFV+  LR   G     P  ++ RLS  V LDPRPEY
Sbjct: 647  IDGVRKIIFALPGNPVSAVVTCNLFVVPALRKMQGILDPRPTIIKARLSCDVKLDPRPEY 706

Query: 789  ARAEIHLSDTDELPTXKLIGNQCSSRLLSACGASVLLELPGRTXSTPQLXAGSVXTALLX 968
             R  +     + LP  +  GNQ SSRL+S   A+ LL LP +T    +L  G V   ++ 
Sbjct: 707  HRCILTWHHQEPLPWAQSTGNQMSSRLMSMRSANGLLMLPPKTEQYVELHKGEVVDVMVI 766

Query: 969  SRL 977
             RL
Sbjct: 767  GRL 769


>AJ272343-1|CAC10537.1|  769|Homo sapiens gephyrin protein.
          Length = 769

 Score =  260 bits (638), Expect = 7e-69
 Identities = 141/303 (46%), Positives = 187/303 (61%), Gaps = 1/303 (0%)
 Frame = +3

Query: 72   EAEDKQTELEVEILIAPQLGQDVRPVGFDIPMGTILVNKGEILDAAKIGVLAGAGYRSIT 251
            E++D   ELEV IL+  + GQD+RP+G DI  G  ++ KG  +  ++IG+LA  G   + 
Sbjct: 468  ESDDGTEELEVRILVQARPGQDIRPIGHDIKRGECVLAKGTHMGPSEIGLLATVGVTEVE 527

Query: 252  AQVNPKVALMSTGNELQEPSEVKLRPAHIRDSNRTMLKALLREHGYDSIDCGIARDTPEE 431
                P VA+MSTGNEL  P +  L P  IRDSNR+ L A ++EHGY +I+ GI  D P++
Sbjct: 528  VNKFPVVAVMSTGNELLNPED-DLLPGKIRDSNRSTLLATIQEHGYPTINLGIVGDNPDD 586

Query: 432  LVAGIATALSRADVLVCTGGVSMGERDLLKPVLLNDFGANLYYGRVRMKPGKPSTFATCQ 611
            L+  +   +SRADV++ +GGVSMGE+D LK VL  D  A +++GRV MKPG P+TFAT  
Sbjct: 587  LLNALNEGISRADVIITSGGVSMGEKDYLKQVLDIDLHAQIHFGRVFMKPGLPTTFATLD 646

Query: 612  FEGKTKYIFALPGNPVSAYVCCLLFVIRGLRVCNGREGAWPR-LRVRLSHAVALDPRPEY 788
             +G  K IFALPGNPVSA V C LFV+  LR   G     P  ++ RLS  V LDPRPEY
Sbjct: 647  IDGVRKIIFALPGNPVSAVVTCNLFVVPALRKMQGILDPRPTIIKARLSCDVKLDPRPEY 706

Query: 789  ARAEIHLSDTDELPTXKLIGNQCSSRLLSACGASVLLELPGRTXSTPQLXAGSVXTALLX 968
             R  +     + LP  +  GNQ SSRL+S   A+ LL LP +T    +L  G V   ++ 
Sbjct: 707  HRCILTWHHQEPLPWAQSTGNQMSSRLMSMRSANGLLMLPPKTEQYVELHKGEVVDVMVI 766

Query: 969  SRL 977
             RL
Sbjct: 767  GRL 769


>AJ272033-1|CAC81240.1|  736|Homo sapiens gephyrin protein.
          Length = 736

 Score =  260 bits (638), Expect = 7e-69
 Identities = 141/303 (46%), Positives = 187/303 (61%), Gaps = 1/303 (0%)
 Frame = +3

Query: 72   EAEDKQTELEVEILIAPQLGQDVRPVGFDIPMGTILVNKGEILDAAKIGVLAGAGYRSIT 251
            E++D   ELEV IL+  + GQD+RP+G DI  G  ++ KG  +  ++IG+LA  G   + 
Sbjct: 435  ESDDGTEELEVRILVQARPGQDIRPIGHDIKRGECVLAKGTHMGPSEIGLLATVGVTEVE 494

Query: 252  AQVNPKVALMSTGNELQEPSEVKLRPAHIRDSNRTMLKALLREHGYDSIDCGIARDTPEE 431
                P VA+MSTGNEL  P +  L P  IRDSNR+ L A ++EHGY +I+ GI  D P++
Sbjct: 495  VNKFPVVAVMSTGNELLNPED-DLLPGKIRDSNRSTLLATIQEHGYPTINLGIVGDNPDD 553

Query: 432  LVAGIATALSRADVLVCTGGVSMGERDLLKPVLLNDFGANLYYGRVRMKPGKPSTFATCQ 611
            L+  +   +SRADV++ +GGVSMGE+D LK VL  D  A +++GRV MKPG P+TFAT  
Sbjct: 554  LLNALNEGISRADVIITSGGVSMGEKDYLKQVLDIDLHAQIHFGRVFMKPGLPTTFATLD 613

Query: 612  FEGKTKYIFALPGNPVSAYVCCLLFVIRGLRVCNGREGAWPR-LRVRLSHAVALDPRPEY 788
             +G  K IFALPGNPVSA V C LFV+  LR   G     P  ++ RLS  V LDPRPEY
Sbjct: 614  IDGVRKIIFALPGNPVSAVVTCNLFVVPALRKMQGILDPRPTIIKARLSCDVKLDPRPEY 673

Query: 789  ARAEIHLSDTDELPTXKLIGNQCSSRLLSACGASVLLELPGRTXSTPQLXAGSVXTALLX 968
             R  +     + LP  +  GNQ SSRL+S   A+ LL LP +T    +L  G V   ++ 
Sbjct: 674  HRCILTWHHQEPLPWAQSTGNQMSSRLMSMRSANGLLMLPPKTEQYVELHKGEVVDVMVI 733

Query: 969  SRL 977
             RL
Sbjct: 734  GRL 736


>AF272663-1|AAF81785.1|  736|Homo sapiens gephyrin protein.
          Length = 736

 Score =  260 bits (638), Expect = 7e-69
 Identities = 141/303 (46%), Positives = 187/303 (61%), Gaps = 1/303 (0%)
 Frame = +3

Query: 72   EAEDKQTELEVEILIAPQLGQDVRPVGFDIPMGTILVNKGEILDAAKIGVLAGAGYRSIT 251
            E++D   ELEV IL+  + GQD+RP+G DI  G  ++ KG  +  ++IG+LA  G   + 
Sbjct: 435  ESDDGTEELEVRILVQARPGQDIRPIGHDIKRGECVLAKGTHMGPSEIGLLATVGVTEVE 494

Query: 252  AQVNPKVALMSTGNELQEPSEVKLRPAHIRDSNRTMLKALLREHGYDSIDCGIARDTPEE 431
                P VA+MSTGNEL  P +  L P  IRDSNR+ L A ++EHGY +I+ GI  D P++
Sbjct: 495  VNKFPVVAVMSTGNELLNPED-DLLPGKIRDSNRSTLLATIQEHGYPTINLGIVGDNPDD 553

Query: 432  LVAGIATALSRADVLVCTGGVSMGERDLLKPVLLNDFGANLYYGRVRMKPGKPSTFATCQ 611
            L+  +   +SRADV++ +GGVSMGE+D LK VL  D  A +++GRV MKPG P+TFAT  
Sbjct: 554  LLNALNEGISRADVIITSGGVSMGEKDYLKQVLDIDLHAQIHFGRVFMKPGLPTTFATLD 613

Query: 612  FEGKTKYIFALPGNPVSAYVCCLLFVIRGLRVCNGREGAWPR-LRVRLSHAVALDPRPEY 788
             +G  K IFALPGNPVSA V C LFV+  LR   G     P  ++ RLS  V LDPRPEY
Sbjct: 614  IDGVRKIIFALPGNPVSAVVTCNLFVVPALRKMQGILDPRPTIIKARLSCDVKLDPRPEY 673

Query: 789  ARAEIHLSDTDELPTXKLIGNQCSSRLLSACGASVLLELPGRTXSTPQLXAGSVXTALLX 968
             R  +     + LP  +  GNQ SSRL+S   A+ LL LP +T    +L  G V   ++ 
Sbjct: 674  HRCILTWHHQEPLPWAQSTGNQMSSRLMSMRSANGLLMLPPKTEQYVELHKGEVVDVMVI 733

Query: 969  SRL 977
             RL
Sbjct: 734  GRL 736


>AB037806-1|BAA92623.1|  768|Homo sapiens KIAA1385 protein protein.
          Length = 768

 Score =  260 bits (638), Expect = 7e-69
 Identities = 141/303 (46%), Positives = 187/303 (61%), Gaps = 1/303 (0%)
 Frame = +3

Query: 72   EAEDKQTELEVEILIAPQLGQDVRPVGFDIPMGTILVNKGEILDAAKIGVLAGAGYRSIT 251
            E++D   ELEV IL+  + GQD+RP+G DI  G  ++ KG  +  ++IG+LA  G   + 
Sbjct: 467  ESDDGTEELEVRILVQARPGQDIRPIGHDIKRGECVLAKGTHMGPSEIGLLATVGVTEVE 526

Query: 252  AQVNPKVALMSTGNELQEPSEVKLRPAHIRDSNRTMLKALLREHGYDSIDCGIARDTPEE 431
                P VA+MSTGNEL  P +  L P  IRDSNR+ L A ++EHGY +I+ GI  D P++
Sbjct: 527  VNKFPVVAVMSTGNELLNPED-DLLPGKIRDSNRSTLLATIQEHGYPTINLGIVGDNPDD 585

Query: 432  LVAGIATALSRADVLVCTGGVSMGERDLLKPVLLNDFGANLYYGRVRMKPGKPSTFATCQ 611
            L+  +   +SRADV++ +GGVSMGE+D LK VL  D  A +++GRV MKPG P+TFAT  
Sbjct: 586  LLNALNEGISRADVIITSGGVSMGEKDYLKQVLDIDLHAQIHFGRVFMKPGLPTTFATLD 645

Query: 612  FEGKTKYIFALPGNPVSAYVCCLLFVIRGLRVCNGREGAWPR-LRVRLSHAVALDPRPEY 788
             +G  K IFALPGNPVSA V C LFV+  LR   G     P  ++ RLS  V LDPRPEY
Sbjct: 646  IDGVRKIIFALPGNPVSAVVTCNLFVVPALRKMQGILDPRPTIIKARLSCDVKLDPRPEY 705

Query: 789  ARAEIHLSDTDELPTXKLIGNQCSSRLLSACGASVLLELPGRTXSTPQLXAGSVXTALLX 968
             R  +     + LP  +  GNQ SSRL+S   A+ LL LP +T    +L  G V   ++ 
Sbjct: 706  HRCILTWHHQEPLPWAQSTGNQMSSRLMSMRSANGLLMLPPKTEQYVELHKGEVVDVMVI 765

Query: 969  SRL 977
             RL
Sbjct: 766  GRL 768


>BC117319-1|AAI17320.1|  257|Homo sapiens TPRXL protein protein.
          Length = 257

 Score = 41.1 bits (92), Expect = 0.010
 Identities = 47/168 (27%), Positives = 78/168 (46%), Gaps = 2/168 (1%)
 Frame = -3

Query: 547 APKSLSSTGFKRSRSPIDTPPVQTSTSARDKAVAIPATSSSGVSRAIPQSILS*PCSLSK 368
           +P S SST    S S   +    +S S+   + + P++SSS  S + P S  S P S S 
Sbjct: 82  SPSSSSSTSSPSSSSSSSSSSPSSSNSSSSSSSSSPSSSSSS-SSSSPSSSSSSPSSSSS 140

Query: 367 AFNIVLFESRICAGRNLTSDGS*SSLPVDIS-ATLGLT*AVMDR*P-APANTPILAASSI 194
           + +     S      + +S  S SS P   S ++ G + +  +  P + +++P  ++SS 
Sbjct: 141 SSSSSPSSSSSSPSSSSSSSSSSSSSPSSSSPSSSGSSPSSSNSSPSSSSSSPSSSSSSP 200

Query: 193 SPLLTSIVPMGISKPTGRTS*PNCGAIRISTSNSVCLSSASCRIXCSP 50
           SP  +S      S  +  TS P+  +   S+ +S C S+A  R   SP
Sbjct: 201 SPRSSSPSSSSSSTSSPSTSSPSSSSPSSSSPSSSCPSAALGRRPQSP 248


>AK092426-1|BAC03887.1|  258|Homo sapiens protein ( Homo sapiens
           cDNA FLJ35107 fis, clone PLACE6006871, moderately
           similar to SUPPRESSOR PROTEIN SRP40. ).
          Length = 258

 Score = 39.5 bits (88), Expect = 0.031
 Identities = 45/168 (26%), Positives = 77/168 (45%), Gaps = 2/168 (1%)
 Frame = -3

Query: 547 APKSLSSTGFKRSRSPIDTPPVQTSTSARDKAVAIPATSSSGVSRAIPQSILS*PCSLSK 368
           +P S SST    S S   +    +S+++   + +   +SSS  S + P S  S P S S 
Sbjct: 82  SPSSSSSTSSPSSSSSSSSSSSPSSSNSSSSSSSSSPSSSSSSSSSSPSSSSSSPSSSSS 141

Query: 367 AFNIVLFESRICAGRNLTSDGS*SSLPVDIS-ATLGLT*AVMDR*P-APANTPILAASSI 194
           + +     S      + +S  S SS P   S ++ G + +  +  P + +++P  ++SS 
Sbjct: 142 SSSSSPSSSSSSPSSSSSSSSSSSSSPSSSSPSSSGSSPSSSNSSPSSSSSSPSSSSSSP 201

Query: 193 SPLLTSIVPMGISKPTGRTS*PNCGAIRISTSNSVCLSSASCRIXCSP 50
           SP  +S      S  +  TS P+  +   S+ +S C S+A  R   SP
Sbjct: 202 SPRSSSPSSSSSSTSSPSTSSPSSSSPSSSSPSSSCPSAALGRRPQSP 249


>U78516-1|AAD03422.1| 1011|Homo sapiens cAMP-regulated guanine
           nucleotide exchange factor II protein.
          Length = 1011

 Score = 33.1 bits (72), Expect = 2.7
 Identities = 21/78 (26%), Positives = 38/78 (48%)
 Frame = +3

Query: 336 IRDSNRTMLKALLREHGYDSIDCGIARDTPEELVAGIATALSRADVLVCTGGVSMGERDL 515
           IR S+  + K    +H Y +I   +A    +E+++ +A  L   + L+     S GE+ +
Sbjct: 664 IRGSDEVLFKVYCMDHTYTTIRVPVATSV-KEVISAVADKLGSGEGLIIVKMSSGGEKVV 722

Query: 516 LKPVLLNDFGANLYYGRV 569
           LKP  ++ F      GR+
Sbjct: 723 LKPNDVSVFTTLTINGRL 740


>BC040183-1|AAH40183.1|  867|Homo sapiens RAPGEF4 protein protein.
          Length = 867

 Score = 33.1 bits (72), Expect = 2.7
 Identities = 21/78 (26%), Positives = 38/78 (48%)
 Frame = +3

Query: 336 IRDSNRTMLKALLREHGYDSIDCGIARDTPEELVAGIATALSRADVLVCTGGVSMGERDL 515
           IR S+  + K    +H Y +I   +A    +E+++ +A  L   + L+     S GE+ +
Sbjct: 520 IRGSDEVLFKVYCMDHTYTTIRVPVATSV-KEVISAVADKLGSGEGLIIVKMSSGGEKVV 578

Query: 516 LKPVLLNDFGANLYYGRV 569
           LKP  ++ F      GR+
Sbjct: 579 LKPNDVSVFTTLTINGRL 596


>AB209681-1|BAD92918.1|  643|Homo sapiens RAP
           guanine-nucleotide-exchange factor 4 variant protein.
          Length = 643

 Score = 33.1 bits (72), Expect = 2.7
 Identities = 21/78 (26%), Positives = 38/78 (48%)
 Frame = +3

Query: 336 IRDSNRTMLKALLREHGYDSIDCGIARDTPEELVAGIATALSRADVLVCTGGVSMGERDL 515
           IR S+  + K    +H Y +I   +A    +E+++ +A  L   + L+     S GE+ +
Sbjct: 296 IRGSDEVLFKVYCMDHTYTTIRVPVATSV-KEVISAVADKLGSGEGLIIVKMSSGGEKVV 354

Query: 516 LKPVLLNDFGANLYYGRV 569
           LKP  ++ F      GR+
Sbjct: 355 LKPNDVSVFTTLTINGRL 372


>AB027471-1|BAB72179.1| 1011|Homo sapiens cAMP-GEFII protein.
          Length = 1011

 Score = 33.1 bits (72), Expect = 2.7
 Identities = 21/78 (26%), Positives = 38/78 (48%)
 Frame = +3

Query: 336 IRDSNRTMLKALLREHGYDSIDCGIARDTPEELVAGIATALSRADVLVCTGGVSMGERDL 515
           IR S+  + K    +H Y +I   +A    +E+++ +A  L   + L+     S GE+ +
Sbjct: 664 IRGSDEVLFKVYCMDHTYTTIRVPVATSV-KEVISAVADKLGSGEGLIIVKMSSGGEKVV 722

Query: 516 LKPVLLNDFGANLYYGRV 569
           LKP  ++ F      GR+
Sbjct: 723 LKPNDVSVFTTLTINGRL 740


>AB075513-1|BAE45759.1|  478|Homo sapiens putative protein product
           of Nbla00496 protein.
          Length = 478

 Score = 32.7 bits (71), Expect = 3.6
 Identities = 18/63 (28%), Positives = 32/63 (50%)
 Frame = +3

Query: 336 IRDSNRTMLKALLREHGYDSIDCGIARDTPEELVAGIATALSRADVLVCTGGVSMGERDL 515
           IR S+  + K    +H Y +I   +A    +E+++ +A  L   + L+     S GE+ +
Sbjct: 131 IRGSDEVLFKVYCMDHTYTTIRVPVATSV-KEVISAVADKLGSGEGLIIVKMSSGGEKVV 189

Query: 516 LKP 524
           LKP
Sbjct: 190 LKP 192


  Database: human
    Posted date:  Oct 23, 2007  1:18 PM
  Number of letters in database: 76,859,062
  Number of sequences in database:  237,096
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 156,684,052
Number of Sequences: 237096
Number of extensions: 3264787
Number of successful extensions: 6864
Number of sequences better than 10.0: 12
Number of HSP's better than 10.0 without gapping: 6444
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 6847
length of database: 76,859,062
effective HSP length: 93
effective length of database: 54,809,134
effective search space used: 22416935806
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

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