Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= 030712_H01_e104_15.seq
(1446 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
BC060857-1|AAH60857.1| 525|Homo sapiens cytochrome P450, family... 144 9e-34
AY422002-1|AAR31180.1| 525|Homo sapiens cytochrome P450 4V2 pro... 144 9e-34
AK122600-1|BAC85487.1| 525|Homo sapiens protein ( Homo sapiens ... 144 9e-34
AK126473-1|BAC86562.1| 503|Homo sapiens protein ( Homo sapiens ... 135 3e-31
BC093896-1|AAH93896.1| 531|Homo sapiens cytochrome P450, family... 82 6e-15
BC093894-1|AAH93894.1| 531|Homo sapiens cytochrome P450, family... 82 6e-15
BC069351-1|AAH69351.1| 531|Homo sapiens cytochrome P450, family... 82 6e-15
AC004523-1|AAC11543.1| 458|Homo sapiens F22329_1 protein. 82 6e-15
BC035350-1|AAH35350.1| 524|Homo sapiens cytochrome P450, family... 81 7e-15
AY358977-1|AAQ89336.1| 524|Homo sapiens CYP4F12 protein. 81 7e-15
AY008841-1|AAG33247.1| 524|Homo sapiens cytochrome P450 isoform... 81 7e-15
AB035131-1|BAB18270.1| 524|Homo sapiens cytochrome P450 protein. 81 7e-15
AB035130-1|BAB18269.1| 524|Homo sapiens cytochrome P450 protein. 81 7e-15
BC016853-1|AAH16853.1| 524|Homo sapiens CYP4F11 protein protein. 81 1e-14
AF236085-1|AAG15889.1| 524|Homo sapiens CYP4F11 protein. 81 1e-14
AK096820-1|BAC04868.1| 531|Homo sapiens protein ( Homo sapiens ... 80 2e-14
AF054821-1|AAC08589.1| 520|Homo sapiens cytochrome P-450 protein. 79 3e-14
D12621-1|BAA02145.1| 389|Homo sapiens cytochrome P-450LTBV prot... 79 4e-14
D12620-1|BAA02144.1| 520|Homo sapiens cytochrome P-450LTBV prot... 79 4e-14
AY792513-1|AAV40834.1| 520|Homo sapiens cytochrome P450, family... 79 4e-14
AB002461-1|BAA25991.1| 520|Homo sapiens leukotriene B4 omega-hy... 79 4e-14
AB002454-1|BAA25990.1| 520|Homo sapiens leukotriene B4 omega-hy... 79 4e-14
AF133298-1|AAD49566.1| 520|Homo sapiens cytochrome P450 protein. 77 1e-13
U02388-1|AAC50052.2| 520|Homo sapiens cytochrome P450 4F2 protein. 77 2e-13
D26480-1|BAA05490.1| 520|Homo sapiens leukotriene B4 omega-hydr... 77 2e-13
BC067439-1|AAH67439.1| 520|Homo sapiens cytochrome P450, family... 77 2e-13
BC067437-1|AAH67437.1| 520|Homo sapiens cytochrome P450, family... 77 2e-13
AF467894-1|AAL67578.1| 520|Homo sapiens cytochrome P450, subfam... 77 2e-13
AC005336-1|AAC27730.1| 520|Homo sapiens CYP4F2 protein. 77 2e-13
AB015306-1|BAA75823.1| 520|Homo sapiens Leukotriene B4 omega-hy... 77 2e-13
BC067440-1|AAH67440.1| 520|Homo sapiens cytochrome P450, family... 77 2e-13
AF221943-1|AAF86378.1| 175|Homo sapiens leukotriene B4 omega hy... 76 3e-13
J02871-1|AAA35712.1| 511|Homo sapiens protein ( Human lung cyto... 76 4e-13
X16699-1|CAA34672.1| 511|Homo sapiens protein ( Human mRNA for ... 74 1e-12
DQ518907-1|ABF47106.1| 511|Homo sapiens cytochrome P450, family... 74 1e-12
BC017758-1|AAH17758.1| 512|Homo sapiens cytochrome P450, family... 74 1e-12
AY151048-1|AAN72311.1| 512|Homo sapiens pulmonary cytochrome P4... 74 1e-12
AY064486-1|AAL57721.1| 511|Homo sapiens cytochrome P450 protein. 74 1e-12
AY064484-1|AAL57719.1| 295|Homo sapiens truncated cytochrome P4... 74 1e-12
AL593856-7|CAI16982.1| 512|Homo sapiens cytochrome P450, family... 74 1e-12
AL593856-6|CAI16981.1| 511|Homo sapiens cytochrome P450, family... 74 1e-12
AL356793-4|CAI22557.1| 512|Homo sapiens cytochrome P450, family... 74 1e-12
AL356793-3|CAI22559.1| 511|Homo sapiens cytochrome P450, family... 74 1e-12
AF491285-1|AAM09532.1| 511|Homo sapiens cytochrome P450 protein. 74 1e-12
AY064485-1|AAL57720.1| 511|Homo sapiens cytochrome P450 protein. 74 1e-12
S67581-1|AAB29503.1| 591|Homo sapiens fatty acid omega-hydroxyl... 71 1e-11
S67580-1|AAB29502.1| 519|Homo sapiens fatty acid omega-hydroxyl... 71 1e-11
L04751-1|AAA58436.1| 519|Homo sapiens cytochrome P450 protein. 71 1e-11
D26481-1|BAA05491.1| 519|Homo sapiens fatty acids omega-hydroxy... 71 1e-11
D13705-1|BAA02864.1| 521|Homo sapiens fatty acid omega-hydroxyl... 71 1e-11
BC041158-1|AAH41158.1| 455|Homo sapiens CYP4A11 protein protein. 71 1e-11
BC022851-1|AAH22851.1| 215|Homo sapiens CYP4A11 protein protein. 71 1e-11
AY369778-1|AAQ56847.1| 519|Homo sapiens cytochrome P450, family... 71 1e-11
AL731892-4|CAH72779.1| 455|Homo sapiens cytochrome P450, family... 71 1e-11
AL731892-3|CAH72778.1| 519|Homo sapiens cytochrome P450, family... 71 1e-11
AF525488-1|AAO16078.1| 519|Homo sapiens cytochrome P450, subfam... 71 1e-11
AY280372-1|AAQ21368.1| 519|Homo sapiens cytochrome P450 4A22 pr... 70 2e-11
BC142607-1|AAI42608.1| 455|Homo sapiens CYP4A22 protein protein. 69 3e-11
BC028102-1|AAH28102.1| 509|Homo sapiens cytochrome P450, family... 69 3e-11
AY358537-1|AAQ88901.1| 509|Homo sapiens EFSW1929 protein. 69 3e-11
AY280371-1|AAQ21367.1| 519|Homo sapiens cytochrome P450 4A22K p... 69 3e-11
AM040940-1|CAJ13826.1| 509|Homo sapiens cytochrome P450 protein. 69 3e-11
AL450996-1|CAH71035.1| 509|Homo sapiens cytochrome P450, family... 69 3e-11
AK098065-1|BAC05226.1| 509|Homo sapiens protein ( Homo sapiens ... 69 3e-11
AK091806-1|BAC03751.1| 444|Homo sapiens protein ( Homo sapiens ... 69 3e-11
AK131355-1|BAD18508.1| 508|Homo sapiens protein ( Homo sapiens ... 69 4e-11
AF208532-1|AAF76722.1| 519|Homo sapiens fatty acid omega-hydrox... 67 2e-10
BC142690-1|AAI42691.1| 357|Homo sapiens CYP4A22 protein protein. 66 2e-10
AY696295-1|AAU10524.1| 292|Homo sapiens cytochrome P450 protein. 66 2e-10
AL135960-11|CAI19738.1| 455|Homo sapiens cytochrome P450, famil... 66 4e-10
AL135960-10|CAI19736.1| 421|Homo sapiens cytochrome P450, famil... 66 4e-10
AL135960-9|CAI19737.1| 519|Homo sapiens cytochrome P450, family... 66 4e-10
AK097373-1|BAC05026.1| 340|Homo sapiens protein ( Homo sapiens ... 66 4e-10
AY358631-1|AAQ88994.1| 505|Homo sapiens EPSW3060 protein. 64 2e-09
AY262056-1|AAO89257.1| 505|Homo sapiens cytochrome P450 protein. 64 2e-09
AL450996-2|CAH71036.1| 505|Homo sapiens cytochrome P450, family... 64 2e-09
AL135960-6|CAI19734.1| 505|Homo sapiens cytochrome P450, family... 64 2e-09
AY151049-1|AAN72312.1| 497|Homo sapiens pulmonary cytochrome P4... 54 1e-06
AL593856-5|CAI16983.1| 497|Homo sapiens cytochrome P450, family... 54 1e-06
AL356793-2|CAI22558.1| 497|Homo sapiens cytochrome P450, family... 54 1e-06
J04449-1|AAA35747.1| 502|Homo sapiens cytochrome P450 nifedipin... 49 5e-05
D00408-1|BAA00310.1| 503|Homo sapiens cytochrome P-450 HFLa pro... 49 5e-05
BC067436-1|AAH67436.1| 503|Homo sapiens cytochrome P450, family... 49 5e-05
AF315325-1|AAG48618.1| 535|Homo sapiens cytochrome P450 variant... 49 5e-05
AF280107-3|AAG32289.1| 503|Homo sapiens cytochrome P450 polypep... 49 5e-05
AJ563375-1|CAD91343.1| 503|Homo sapiens cytochrome P450 protein. 48 6e-05
X12387-1|CAA30944.1| 503|Homo sapiens protein ( Human mRNA for ... 48 9e-05
M18907-1|AAA35745.1| 503|Homo sapiens protein ( Human P450 mRNA... 48 9e-05
M14096-1|AAA35744.1| 503|Homo sapiens protein ( Human cytochrom... 48 9e-05
DQ924960-1|ABI96208.1| 503|Homo sapiens cytochrome P450 family ... 48 9e-05
DQ005611-1|AAY16980.1| 503|Homo sapiens cytochrome P450, family... 48 9e-05
BC101631-1|AAI01632.1| 503|Homo sapiens cytochrome P450, subfam... 48 9e-05
BC069418-1|AAH69418.1| 503|Homo sapiens cytochrome P450, family... 48 9e-05
AF280107-2|AAG32290.1| 503|Homo sapiens cytochrome P450 polypep... 48 9e-05
AF209389-1|AAF21034.1| 503|Homo sapiens cytochrome P450 IIIA4 p... 48 9e-05
AF182273-1|AAF13598.1| 503|Homo sapiens cytochrome P450-3A4 pro... 47 1e-04
M13785-1|AAA35742.1| 504|Homo sapiens protein ( Human liver glu... 44 0.002
D00003-1|BAA00001.1| 504|Homo sapiens cytochrome P-450 protein. 44 0.002
EF122242-1|ABO41977.1| 321|Homo sapiens cytochrome P450 2F1 var... 42 0.006
AY390425-1|AAQ92353.1| 503|Homo sapiens cytochrome P450 CYP3A43... 41 0.010
AY390424-1|AAQ92352.1| 503|Homo sapiens cytochrome P450 CYP3A43... 41 0.010
AF337813-1|AAK38841.1| 503|Homo sapiens cytochrome P450 subfami... 41 0.010
AF319634-1|AAK00325.1| 503|Homo sapiens cytochrome P450 CYP3A43... 41 0.010
AF280111-1|AAG33012.1| 250|Homo sapiens cytochrome P450 subfami... 41 0.010
AF280110-1|AAG33011.1| 420|Homo sapiens cytochrome P450 subfami... 41 0.010
AF280109-1|AAG33010.1| 504|Homo sapiens cytochrome P450 subfami... 41 0.010
AF280108-1|AAG33009.1| 503|Homo sapiens cytochrome P450 subfami... 41 0.010
AC011904-5|AAS07394.1| 504|Homo sapiens unknown protein. 41 0.010
AC011904-4|AAS07395.1| 503|Homo sapiens unknown protein. 41 0.010
BC033691-1|AAH33691.1| 504|Homo sapiens cytochrome P450, family... 40 0.030
AY358603-1|AAQ88966.1| 504|Homo sapiens Cytochrome p450 protein. 40 0.030
AK027605-1|BAB55227.1| 564|Homo sapiens protein ( Homo sapiens ... 40 0.030
AF335278-1|AAK13498.1| 504|Homo sapiens cytochrome P450 2S1 pro... 40 0.030
J04813-1|AAA02993.1| 502|Homo sapiens cytochrome P450 PCN3 prot... 39 0.052
J02906-1|AAA52156.1| 491|Homo sapiens CYP2F1 protein. 39 0.052
EF122241-1|ABO41976.1| 491|Homo sapiens cytochrome P450 2F1 var... 39 0.052
DQ680079-1|ABG25922.1| 347|Homo sapiens truncated cytochrome P4... 39 0.052
BC109056-1|AAI09057.1| 320|Homo sapiens CYP2F1 protein protein. 39 0.052
BC033862-1|AAH33862.1| 502|Homo sapiens cytochrome P450, family... 39 0.052
AF372573-1|AAL69652.1| 495|Homo sapiens cytochrome P450 2F1 pro... 39 0.052
AC005020-1|AAS02016.1| 502|Homo sapiens unknown protein. 39 0.052
AK223008-1|BAD96728.1| 502|Homo sapiens cytochrome P450, family... 38 0.069
BC070317-1|AAH70317.1| 162|Homo sapiens CYP2C9 protein protein. 38 0.091
BC020754-1|AAH20754.1| 162|Homo sapiens CYP2C9 protein protein. 38 0.12
U22028-1|AAB40519.1| 494|Homo sapiens cytochrome P450 protein. 36 0.28
AY513609-1|AAR90940.1| 494|Homo sapiens cytochrome P450 2A13 va... 36 0.28
AY513608-1|AAR90939.1| 494|Homo sapiens cytochrome P450 2A13 va... 36 0.28
AY513606-1|AAR90937.1| 494|Homo sapiens cytochrome P450 2A13 va... 36 0.28
AY513605-1|AAR90936.1| 494|Homo sapiens cytochrome P450 2A13 va... 36 0.28
AY513604-1|AAR90935.1| 494|Homo sapiens cytochrome P450 2A13 va... 36 0.28
AJ563376-2|CAD91645.1| 430|Homo sapiens cytochrome P450 protein. 36 0.28
AF209774-1|AAG35775.1| 494|Homo sapiens cytochrome P450 2A13 pr... 36 0.28
X13930-1|CAA32118.1| 494|Homo sapiens protein ( Human CYP2A4 mR... 36 0.37
L16880-1|AAD13466.1| 273|Homo sapiens cytochrome P-450 2C protein. 36 0.37
BC125054-1|AAI25055.1| 490|Homo sapiens cytochrome P450, family... 36 0.37
BC096255-1|AAH96255.1| 494|Homo sapiens cytochrome P450, family... 36 0.37
AY702706-1|AAT94065.1| 490|Homo sapiens cytochrome P450, family... 36 0.37
AY341248-1|AAP88931.1| 490|Homo sapiens cytochrome P450, family... 36 0.37
AL359672-1|CAH71303.1| 490|Homo sapiens cytochrome P450, family... 36 0.37
D00173-1|BAA00123.1| 487|Homo sapiens cytochrome P-450 protein. 36 0.49
X13897-1|CAA32097.1| 489|Homo sapiens protein ( Human mRNA for ... 35 0.64
M33318-1|AAA52067.1| 494|Homo sapiens CYP2A protein. 35 0.64
BC096256-1|AAH96256.1| 494|Homo sapiens cytochrome P450, family... 35 0.64
BC096254-1|AAH96254.1| 494|Homo sapiens cytochrome P450, family... 35 0.64
BC096253-1|AAH96253.3| 494|Homo sapiens cytochrome P450, family... 35 0.64
AF182275-1|AAF13600.1| 494|Homo sapiens cytochrome P450-2A6 pro... 35 0.64
M21939-1|AAA52158.1| 485|Homo sapiens CYP2C protein. 35 0.85
M15331-1|AAA52157.1| 485|Homo sapiens CYP2C protein. 35 0.85
M29874-1|AAA52144.1| 491|Homo sapiens CYP2B protein. 34 1.1
DQ298753-1|ABB84469.1| 491|Homo sapiens cytochrome P450, family... 34 1.1
BC067431-1|AAH67431.1| 491|Homo sapiens cytochrome P450, family... 34 1.1
AF182277-1|AAF13602.1| 491|Homo sapiens cytochrome P450-2B6 pro... 34 1.1
AC023172-1|AAF32444.1| 491|Homo sapiens CYP2B6 protein. 34 1.1
M29873-1|AAA52143.1| 377|Homo sapiens CYP2B protein. 34 1.5
BC067430-1|AAH67430.1| 491|Homo sapiens cytochrome P450, family... 34 1.5
BC041174-1|AAH41174.1| 377|Homo sapiens CYP2B7P1 protein protein. 34 1.5
S46963-1|AAB23864.2| 477|Homo sapiens cytochrome P-450 protein. 33 2.0
Y00498-1|CAA68550.1| 490|Homo sapiens IIC2 protein. 33 2.6
BC020596-1|AAH20596.1| 490|Homo sapiens cytochrome P450, family... 33 2.6
AY514490-1|AAR89907.1| 490|Homo sapiens cytochrome P450, family... 33 2.6
AL359672-5|CAH71307.1| 490|Homo sapiens cytochrome P450, family... 33 2.6
M21941-1|AAA52160.1| 480|Homo sapiens CYP2C protein. 32 4.5
M61856-1|AAB59356.1| 490|Homo sapiens cytochrome protein. 32 6.0
M17398-1|AAA35740.1| 393|Homo sapiens protein ( Human cytochrom... 32 6.0
M17397-1|AAA35739.1| 490|Homo sapiens protein ( Human cytochrom... 32 6.0
L16876-1|AAA02630.1| 490|Homo sapiens cytochrome P-4502C18 prot... 32 6.0
BC096260-1|AAH96260.1| 431|Homo sapiens CYP2C18 protein protein. 32 6.0
BC096259-1|AAH96259.1| 443|Homo sapiens CYP2C18 protein protein. 32 6.0
BC096258-1|AAH96258.1| 490|Homo sapiens cytochrome P450, family... 32 6.0
BC096257-1|AAH96257.1| 490|Homo sapiens cytochrome P450, family... 32 6.0
BC069666-1|AAH69666.1| 490|Homo sapiens cytochrome P450, family... 32 6.0
AL583836-1|CAH74067.1| 490|Homo sapiens cytochrome P450, family... 32 6.0
AK223510-1|BAD97230.1| 490|Homo sapiens cytochrome P450, family... 32 6.0
BX928748-1|CAH74051.1| 5635|Homo sapiens protein ( Human DNA seq... 31 7.9
BC104909-1|AAI04910.1| 501|Homo sapiens cytochrome P450, family... 31 7.9
BC104907-1|AAI04908.1| 501|Homo sapiens cytochrome P450, family... 31 7.9
AY323817-1|AAQ23114.1| 501|Homo sapiens cytochrome P450 2R1 pro... 31 7.9
AL391824-1|CAI17865.1| 5635|Homo sapiens protein ( Human DNA seq... 31 7.9
AL135797-1|CAI17871.1| 5635|Homo sapiens protein ( Human DNA seq... 31 7.9
AL135796-1|CAI17854.1| 5635|Homo sapiens protein ( Human DNA seq... 31 7.9
AL133553-2|CAI17858.1| 5635|Homo sapiens protein ( Human DNA seq... 31 7.9
AL133515-1|CAI17853.1| 5635|Homo sapiens protein ( Human DNA seq... 31 7.9
AL121996-1|CAI17844.1| 5635|Homo sapiens protein ( Human DNA seq... 31 7.9
AL118512-1|CAI17864.1| 5635|Homo sapiens protein ( Human DNA seq... 31 7.9
AJ306906-1|CAC37630.1| 2673|Homo sapiens fibulin-6 protein. 31 7.9
AF156100-1|AAK68690.1| 5636|Homo sapiens hemicentin protein. 31 7.9
>BC060857-1|AAH60857.1| 525|Homo sapiens cytochrome P450, family 4,
subfamily V, polypeptide 2 protein.
Length = 525
Score = 144 bits (348), Expect = 9e-34
Identities = 65/152 (42%), Positives = 98/152 (64%), Gaps = 2/152 (1%)
Frame = +3
Query: 342 KGLPLIGNALEFVGGSAEIFSNIIQKSLAFDNESVVKIWIGPRLLVFLYDPRDVEVILSS 521
+ PL+G+AL E F II+ + + + ++K+W+GP +V LY+ +VEVIL+S
Sbjct: 55 RAYPLVGHALLMKPDGREFFQQIIEYTEEYRHMPLLKLWVGPVPMVALYNAENVEVILTS 114
Query: 522 HVHIDKADEYRFFKPWLGNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVV 701
IDK+ Y+F +PWLG GLL STG KWRS RK++ PTFH +L+ F+D+ N + +V
Sbjct: 115 SKQIDKSSMYKFLEPWLGLGLLTSTGNKWRSRRKMLTPTFHFTILEDFLDIMNEQANILV 174
Query: 702 EKLNKEAG--TFDCHDYMSECTVEILLETAMG 791
+KL K F+C Y++ C ++I+ ETAMG
Sbjct: 175 KKLEKHINQEAFNCFFYITLCALDIICETAMG 206
>AY422002-1|AAR31180.1| 525|Homo sapiens cytochrome P450 4V2
protein.
Length = 525
Score = 144 bits (348), Expect = 9e-34
Identities = 65/152 (42%), Positives = 98/152 (64%), Gaps = 2/152 (1%)
Frame = +3
Query: 342 KGLPLIGNALEFVGGSAEIFSNIIQKSLAFDNESVVKIWIGPRLLVFLYDPRDVEVILSS 521
+ PL+G+AL E F II+ + + + ++K+W+GP +V LY+ +VEVIL+S
Sbjct: 55 RAYPLVGHALLMKPDGREFFQQIIEYTEEYRHMPLLKLWVGPVPMVALYNAENVEVILTS 114
Query: 522 HVHIDKADEYRFFKPWLGNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVV 701
IDK+ Y+F +PWLG GLL STG KWRS RK++ PTFH +L+ F+D+ N + +V
Sbjct: 115 SKQIDKSSMYKFLEPWLGLGLLTSTGNKWRSRRKMLTPTFHFTILEDFLDIMNEQANILV 174
Query: 702 EKLNKEAG--TFDCHDYMSECTVEILLETAMG 791
+KL K F+C Y++ C ++I+ ETAMG
Sbjct: 175 KKLEKHINQEAFNCFFYITLCALDIICETAMG 206
>AK122600-1|BAC85487.1| 525|Homo sapiens protein ( Homo sapiens
cDNA FLJ16007 fis, clone KIDNE2006580, weakly similar
to CYTOCHROME P450 4C1 (EC 1.14.14.1). ).
Length = 525
Score = 144 bits (348), Expect = 9e-34
Identities = 65/152 (42%), Positives = 98/152 (64%), Gaps = 2/152 (1%)
Frame = +3
Query: 342 KGLPLIGNALEFVGGSAEIFSNIIQKSLAFDNESVVKIWIGPRLLVFLYDPRDVEVILSS 521
+ PL+G+AL E F II+ + + + ++K+W+GP +V LY+ +VEVIL+S
Sbjct: 55 RAYPLVGHALLMKPDGREFFQQIIEYTEEYRHMPLLKLWVGPVPMVALYNAENVEVILTS 114
Query: 522 HVHIDKADEYRFFKPWLGNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVV 701
IDK+ Y+F +PWLG GLL STG KWRS RK++ PTFH +L+ F+D+ N + +V
Sbjct: 115 SKQIDKSSMYKFLEPWLGLGLLTSTGNKWRSRRKMLTPTFHFTILEDFLDIMNEQANILV 174
Query: 702 EKLNKEAG--TFDCHDYMSECTVEILLETAMG 791
+KL K F+C Y++ C ++I+ ETAMG
Sbjct: 175 KKLEKHINQEAFNCFFYITLCALDIICETAMG 206
>AK126473-1|BAC86562.1| 503|Homo sapiens protein ( Homo sapiens
cDNA FLJ44509 fis, clone UTERU3001585, weakly similar
to Cytochrome P450 4c3 (EC 1.14.-.-). ).
Length = 503
Score = 135 bits (327), Expect = 3e-31
Identities = 60/135 (44%), Positives = 90/135 (66%), Gaps = 2/135 (1%)
Frame = +3
Query: 393 EIFSNIIQKSLAFDNESVVKIWIGPRLLVFLYDPRDVEVILSSHVHIDKADEYRFFKPWL 572
E F II+ + + + ++K+W+GP +V LY+ +VEVIL+S IDK+ Y+F +PWL
Sbjct: 50 EFFQQIIEYTEEYRHMPLLKLWVGPVPMVALYNAENVEVILTSSKQIDKSSMYKFLEPWL 109
Query: 573 GNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVEKLNKEAG--TFDCHDY 746
G GLL STG KWRS RK++ PTFH +L+ F+D+ N + +V+KL K F+C Y
Sbjct: 110 GLGLLTSTGNKWRSRRKMLTPTFHFTILEDFLDIMNEQANILVKKLEKHINQEAFNCFFY 169
Query: 747 MSECTVEILLETAMG 791
++ C ++I+ ETAMG
Sbjct: 170 ITLCALDIICETAMG 184
>BC093896-1|AAH93896.1| 531|Homo sapiens cytochrome P450, family 4,
subfamily F, polypeptide 22 protein.
Length = 531
Score = 81.8 bits (193), Expect = 6e-15
Identities = 43/141 (30%), Positives = 77/141 (54%), Gaps = 7/141 (4%)
Frame = +3
Query: 414 QKSLAFDNESVVKIWIGPRL-LVFLYDPRDVEVILSSHVHIDKADE--YRFFKPWLGNGL 584
+K + + V+ +W+GP L L+ L P ++ +L + I D+ Y F KPWLG+GL
Sbjct: 85 EKKVLDNMHHVLLVWMGPVLPLLVLVHPDYIKPLLGASAAIAPKDDLFYGFLKPWLGDGL 144
Query: 585 LISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVEK----LNKEAGTFDCHDYMS 752
L+S G KW HR+L+ P FH ++LK ++ +FN ++ + K A + D +++S
Sbjct: 145 LLSKGDKWSRHRRLLTPAFHFDILKPYMKIFNQSADIMHAKWRHLAEGSAVSLDMFEHIS 204
Query: 753 ECTVEILLETAMGVSKTTQDQ 815
T++ L + + Q++
Sbjct: 205 LMTLDSLQKCVFSYNSNCQEK 225
>BC093894-1|AAH93894.1| 531|Homo sapiens cytochrome P450, family 4,
subfamily F, polypeptide 22 protein.
Length = 531
Score = 81.8 bits (193), Expect = 6e-15
Identities = 43/141 (30%), Positives = 77/141 (54%), Gaps = 7/141 (4%)
Frame = +3
Query: 414 QKSLAFDNESVVKIWIGPRL-LVFLYDPRDVEVILSSHVHIDKADE--YRFFKPWLGNGL 584
+K + + V+ +W+GP L L+ L P ++ +L + I D+ Y F KPWLG+GL
Sbjct: 85 EKKVLDNMHHVLLVWMGPVLPLLVLVHPDYIKPLLGASAAIAPKDDLFYGFLKPWLGDGL 144
Query: 585 LISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVEK----LNKEAGTFDCHDYMS 752
L+S G KW HR+L+ P FH ++LK ++ +FN ++ + K A + D +++S
Sbjct: 145 LLSKGDKWSRHRRLLTPAFHFDILKPYMKIFNQSADIMHAKWRHLAEGSAVSLDMFEHIS 204
Query: 753 ECTVEILLETAMGVSKTTQDQ 815
T++ L + + Q++
Sbjct: 205 LMTLDSLQKCVFSYNSNCQEK 225
>BC069351-1|AAH69351.1| 531|Homo sapiens cytochrome P450, family 4,
subfamily F, polypeptide 22 protein.
Length = 531
Score = 81.8 bits (193), Expect = 6e-15
Identities = 43/141 (30%), Positives = 77/141 (54%), Gaps = 7/141 (4%)
Frame = +3
Query: 414 QKSLAFDNESVVKIWIGPRL-LVFLYDPRDVEVILSSHVHIDKADE--YRFFKPWLGNGL 584
+K + + V+ +W+GP L L+ L P ++ +L + I D+ Y F KPWLG+GL
Sbjct: 85 EKKVLDNMHHVLLVWMGPVLPLLVLVHPDYIKPLLGASAAIAPKDDLFYGFLKPWLGDGL 144
Query: 585 LISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVEK----LNKEAGTFDCHDYMS 752
L+S G KW HR+L+ P FH ++LK ++ +FN ++ + K A + D +++S
Sbjct: 145 LLSKGDKWSRHRRLLTPAFHFDILKPYMKIFNQSADIMHAKWRHLAEGSAVSLDMFEHIS 204
Query: 753 ECTVEILLETAMGVSKTTQDQ 815
T++ L + + Q++
Sbjct: 205 LMTLDSLQKCVFSYNSNCQEK 225
>AC004523-1|AAC11543.1| 458|Homo sapiens F22329_1 protein.
Length = 458
Score = 81.8 bits (193), Expect = 6e-15
Identities = 40/128 (31%), Positives = 70/128 (54%), Gaps = 7/128 (5%)
Frame = +3
Query: 453 IWIGPRL-LVFLYDPRDVEVILSSHVHIDKADEY--RFFKPWLGNGLLISTGQKWRSHRK 623
IW+GP + + L P + I ++ I D RF KPWLG G+L+S G KW HR+
Sbjct: 24 IWLGPIIPFIVLCHPDTIRSITNASAAIAPKDNLFIRFLKPWLGEGILLSGGDKWSRHRR 83
Query: 624 LIAPTFHLNVLKSFIDLFNANSRAVVEK----LNKEAGTFDCHDYMSECTVEILLETAMG 791
++ P FH N+LKS+I +FN ++ +++K ++ + D +++S T++ L +
Sbjct: 84 MLTPAFHFNILKSYITIFNKSANIMLDKWQHLASEGSSCLDMFEHISLMTLDSLQKCIFS 143
Query: 792 VSKTTQDQ 815
Q++
Sbjct: 144 FDSHCQER 151
>BC035350-1|AAH35350.1| 524|Homo sapiens cytochrome P450, family 4,
subfamily F, polypeptide 12 protein.
Length = 524
Score = 81.4 bits (192), Expect = 7e-15
Identities = 39/128 (30%), Positives = 70/128 (54%), Gaps = 7/128 (5%)
Frame = +3
Query: 453 IWIGPRL-LVFLYDPRDVEVILSSHVHIDKADEY--RFFKPWLGNGLLISTGQKWRSHRK 623
+W+GP + + L P + I ++ I D RF KPWLG G+L+S G KW HR+
Sbjct: 90 VWLGPIIPFIVLCHPDTIRSITNASAAIAPKDNLFIRFLKPWLGEGILLSGGDKWSRHRR 149
Query: 624 LIAPTFHLNVLKSFIDLFNANSRAVVEK----LNKEAGTFDCHDYMSECTVEILLETAMG 791
++ P FH N+LKS+I +FN ++ +++K ++ + D +++S T++ L +
Sbjct: 150 MLTPAFHFNILKSYITIFNKSANIMLDKWQHLASEGSSCLDMFEHISLMTLDSLQKCIFS 209
Query: 792 VSKTTQDQ 815
Q++
Sbjct: 210 FDSHCQER 217
>AY358977-1|AAQ89336.1| 524|Homo sapiens CYP4F12 protein.
Length = 524
Score = 81.4 bits (192), Expect = 7e-15
Identities = 39/128 (30%), Positives = 70/128 (54%), Gaps = 7/128 (5%)
Frame = +3
Query: 453 IWIGPRL-LVFLYDPRDVEVILSSHVHIDKADEY--RFFKPWLGNGLLISTGQKWRSHRK 623
+W+GP + + L P + I ++ I D RF KPWLG G+L+S G KW HR+
Sbjct: 90 VWLGPIIPFIVLCHPDTIRSITNASAAIAPKDNLFIRFLKPWLGEGILLSGGDKWSRHRR 149
Query: 624 LIAPTFHLNVLKSFIDLFNANSRAVVEK----LNKEAGTFDCHDYMSECTVEILLETAMG 791
++ P FH N+LKS+I +FN ++ +++K ++ + D +++S T++ L +
Sbjct: 150 MLTPAFHFNILKSYITIFNKSANIMLDKWQHLASEGSSRLDMFEHISLMTLDSLQKCIFS 209
Query: 792 VSKTTQDQ 815
Q++
Sbjct: 210 FDSHCQER 217
>AY008841-1|AAG33247.1| 524|Homo sapiens cytochrome P450 isoform
4F12 protein.
Length = 524
Score = 81.4 bits (192), Expect = 7e-15
Identities = 39/128 (30%), Positives = 70/128 (54%), Gaps = 7/128 (5%)
Frame = +3
Query: 453 IWIGPRL-LVFLYDPRDVEVILSSHVHIDKADEY--RFFKPWLGNGLLISTGQKWRSHRK 623
+W+GP + + L P + I ++ I D RF KPWLG G+L+S G KW HR+
Sbjct: 90 VWLGPIIPFIVLCHPDTIRSITNASAAIAPKDNLFIRFLKPWLGEGILLSGGDKWSRHRR 149
Query: 624 LIAPTFHLNVLKSFIDLFNANSRAVVEK----LNKEAGTFDCHDYMSECTVEILLETAMG 791
++ P FH N+LKS+I +FN ++ +++K ++ + D +++S T++ L +
Sbjct: 150 MLTPAFHFNILKSYITIFNKSANIMLDKWQHLASEGSSRLDMFEHISLMTLDSLQKCIFS 209
Query: 792 VSKTTQDQ 815
Q++
Sbjct: 210 FDSHCQER 217
>AB035131-1|BAB18270.1| 524|Homo sapiens cytochrome P450 protein.
Length = 524
Score = 81.4 bits (192), Expect = 7e-15
Identities = 39/128 (30%), Positives = 70/128 (54%), Gaps = 7/128 (5%)
Frame = +3
Query: 453 IWIGPRL-LVFLYDPRDVEVILSSHVHIDKADEY--RFFKPWLGNGLLISTGQKWRSHRK 623
+W+GP + + L P + I ++ I D RF KPWLG G+L+S G KW HR+
Sbjct: 90 VWLGPIIPFIVLCHPDTIRSITNASAAIAPKDNLFIRFLKPWLGEGILLSGGDKWSRHRR 149
Query: 624 LIAPTFHLNVLKSFIDLFNANSRAVVEK----LNKEAGTFDCHDYMSECTVEILLETAMG 791
++ P FH N+LKS+I +FN ++ +++K ++ + D +++S T++ L +
Sbjct: 150 MLTPAFHFNILKSYITIFNKSANIMLDKWQHLASEGSSRLDMFEHISLMTLDSLQKCIFS 209
Query: 792 VSKTTQDQ 815
Q++
Sbjct: 210 FDSHCQER 217
>AB035130-1|BAB18269.1| 524|Homo sapiens cytochrome P450 protein.
Length = 524
Score = 81.4 bits (192), Expect = 7e-15
Identities = 39/128 (30%), Positives = 70/128 (54%), Gaps = 7/128 (5%)
Frame = +3
Query: 453 IWIGPRL-LVFLYDPRDVEVILSSHVHIDKADEY--RFFKPWLGNGLLISTGQKWRSHRK 623
+W+GP + + L P + I ++ I D RF KPWLG G+L+S G KW HR+
Sbjct: 90 VWLGPIIPFIVLCHPDTIRSITNASAAIAPKDNLFIRFLKPWLGEGILLSGGDKWSRHRR 149
Query: 624 LIAPTFHLNVLKSFIDLFNANSRAVVEK----LNKEAGTFDCHDYMSECTVEILLETAMG 791
++ P FH N+LKS+I +FN ++ +++K ++ + D +++S T++ L +
Sbjct: 150 MLTPAFHFNILKSYITIFNKSANIMLDKWQHLASEGSSRLDMFEHISLMTLDSLQKCIFS 209
Query: 792 VSKTTQDQ 815
Q++
Sbjct: 210 FDSHCQER 217
>BC016853-1|AAH16853.1| 524|Homo sapiens CYP4F11 protein protein.
Length = 524
Score = 80.6 bits (190), Expect = 1e-14
Identities = 41/129 (31%), Positives = 68/129 (52%), Gaps = 7/129 (5%)
Frame = +3
Query: 450 KIWIGPRL-LVFLYDPRDVEVILSSHVHIDKADE--YRFFKPWLGNGLLISTGQKWRSHR 620
K+W+GP L+ L P + I S+ + D Y F KPWLG+GLL+S G KW HR
Sbjct: 89 KLWLGPTFPLLILCHPDIIRPITSASAAVAPKDMIFYGFLKPWLGDGLLLSGGDKWSRHR 148
Query: 621 KLIAPTFHLNVLKSFIDLFNANSRAVVEKLNKEA----GTFDCHDYMSECTVEILLETAM 788
+++ P FH N+LK ++ +FN + + +K + A D +++S T++ L +
Sbjct: 149 RMLTPAFHFNILKPYMKIFNKSVNIMHDKWQRLASEGSARLDMFEHISLMTLDSLQKCVF 208
Query: 789 GVSKTTQDQ 815
Q++
Sbjct: 209 SFESNCQEK 217
>AF236085-1|AAG15889.1| 524|Homo sapiens CYP4F11 protein.
Length = 524
Score = 80.6 bits (190), Expect = 1e-14
Identities = 41/129 (31%), Positives = 68/129 (52%), Gaps = 7/129 (5%)
Frame = +3
Query: 450 KIWIGPRL-LVFLYDPRDVEVILSSHVHIDKADE--YRFFKPWLGNGLLISTGQKWRSHR 620
K+W+GP L+ L P + I S+ + D Y F KPWLG+GLL+S G KW HR
Sbjct: 89 KLWLGPTFPLLILCHPDIIRPITSASAAVAPKDMIFYGFLKPWLGDGLLLSGGDKWSRHR 148
Query: 621 KLIAPTFHLNVLKSFIDLFNANSRAVVEKLNKEA----GTFDCHDYMSECTVEILLETAM 788
+++ P FH N+LK ++ +FN + + +K + A D +++S T++ L +
Sbjct: 149 RMLTPAFHFNILKPYMKIFNKSVNIMHDKWQRLASEGSARLDMFEHISLMTLDSLQKCVF 208
Query: 789 GVSKTTQDQ 815
Q++
Sbjct: 209 SFESNCQEK 217
>AK096820-1|BAC04868.1| 531|Homo sapiens protein ( Homo sapiens
cDNA FLJ39501 fis, clone PROST2016980, moderately
similar to CYTOCHROME P450 4F2 (EC 1.14.13.30). ).
Length = 531
Score = 79.8 bits (188), Expect = 2e-14
Identities = 42/141 (29%), Positives = 76/141 (53%), Gaps = 7/141 (4%)
Frame = +3
Query: 414 QKSLAFDNESVVKIWIGPRL-LVFLYDPRDVEVILSSHVHIDKADE--YRFFKPWLGNGL 584
+K + + V+ +W+GP L L+ L P ++ +L + D+ Y F KPWLG+GL
Sbjct: 85 EKKVLDNMHHVLLVWMGPVLPLLVLVHPDYIKPLLGASAATAPKDDLFYGFLKPWLGDGL 144
Query: 585 LISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVEK----LNKEAGTFDCHDYMS 752
L+S G KW HR+L+ P FH ++LK ++ +FN ++ + K A + D +++S
Sbjct: 145 LLSKGDKWSRHRRLLTPAFHFDILKPYMKIFNQSADIMHAKWRHLAEGSAVSLDMFEHIS 204
Query: 753 ECTVEILLETAMGVSKTTQDQ 815
T++ L + + Q++
Sbjct: 205 LMTLDSLQKCVFSYNSNCQEK 225
>AF054821-1|AAC08589.1| 520|Homo sapiens cytochrome P-450 protein.
Length = 520
Score = 79.4 bits (187), Expect = 3e-14
Identities = 39/129 (30%), Positives = 69/129 (53%), Gaps = 7/129 (5%)
Frame = +3
Query: 450 KIWIGPRLLVFLY-DPRDVEVILSSHVHIDKADE--YRFFKPWLGNGLLISTGQKWRSHR 620
K+W+GP V + P + ++++ I D+ Y F KPWLG+GLL+S G+KW HR
Sbjct: 89 KVWMGPIFPVIRFCHPNIIRSVINASAAIVPKDKVFYSFLKPWLGDGLLLSAGEKWSRHR 148
Query: 621 KLIAPTFHLNVLKSFIDLFNANSRAVVEK----LNKEAGTFDCHDYMSECTVEILLETAM 788
+++ P FH N+LK ++ +FN + + K +K D +++S T++ L +
Sbjct: 149 RMLTPAFHFNILKPYMKIFNESVNIMHAKWQLLASKGYARLDMFEHISLMTLDSLQKCVF 208
Query: 789 GVSKTTQDQ 815
Q++
Sbjct: 209 SFDSHCQEK 217
>D12621-1|BAA02145.1| 389|Homo sapiens cytochrome P-450LTBV
protein.
Length = 389
Score = 79.0 bits (186), Expect = 4e-14
Identities = 38/127 (29%), Positives = 70/127 (55%), Gaps = 7/127 (5%)
Frame = +3
Query: 456 WIGP-RLLVFLYDPRDVEVILSSHVHIDKADE--YRFFKPWLGNGLLISTGQKWRSHRKL 626
W+GP +V ++ P ++ +L + I D+ Y F KPWLG+GLL+S G+KW HR++
Sbjct: 91 WVGPWHAIVRIFHPTYIKPVLFAPAAIVPKDKVFYSFLKPWLGDGLLLSAGEKWSRHRRM 150
Query: 627 IAPTFHLNVLKSFIDLFNANSRAVVEK----LNKEAGTFDCHDYMSECTVEILLETAMGV 794
+ P FH N+LK ++ +FN + + K ++ + D +++S T++ L +
Sbjct: 151 LTPAFHFNILKPYMKIFNESVNIMHAKWQLLASEGSARLDMFEHISLMTLDSLQKCVFSF 210
Query: 795 SKTTQDQ 815
Q++
Sbjct: 211 DSHCQEK 217
>D12620-1|BAA02144.1| 520|Homo sapiens cytochrome P-450LTBV
protein.
Length = 520
Score = 79.0 bits (186), Expect = 4e-14
Identities = 38/127 (29%), Positives = 70/127 (55%), Gaps = 7/127 (5%)
Frame = +3
Query: 456 WIGP-RLLVFLYDPRDVEVILSSHVHIDKADE--YRFFKPWLGNGLLISTGQKWRSHRKL 626
W+GP +V ++ P ++ +L + I D+ Y F KPWLG+GLL+S G+KW HR++
Sbjct: 91 WVGPWHAIVRIFHPTYIKPVLFAPAAIVPKDKVFYSFLKPWLGDGLLLSAGEKWSRHRRM 150
Query: 627 IAPTFHLNVLKSFIDLFNANSRAVVEK----LNKEAGTFDCHDYMSECTVEILLETAMGV 794
+ P FH N+LK ++ +FN + + K ++ + D +++S T++ L +
Sbjct: 151 LTPAFHFNILKPYMKIFNESVNIMHAKWQLLASEGSARLDMFEHISLMTLDSLQKCVFSF 210
Query: 795 SKTTQDQ 815
Q++
Sbjct: 211 DSHCQEK 217
>AY792513-1|AAV40834.1| 520|Homo sapiens cytochrome P450, family 4,
subfamily F, polypeptide 3 protein.
Length = 520
Score = 79.0 bits (186), Expect = 4e-14
Identities = 38/127 (29%), Positives = 70/127 (55%), Gaps = 7/127 (5%)
Frame = +3
Query: 456 WIGP-RLLVFLYDPRDVEVILSSHVHIDKADE--YRFFKPWLGNGLLISTGQKWRSHRKL 626
W+GP +V ++ P ++ +L + I D+ Y F KPWLG+GLL+S G+KW HR++
Sbjct: 91 WVGPWHAIVRIFHPTYIKPVLFAPAAIVPKDKVFYSFLKPWLGDGLLLSAGEKWSRHRRM 150
Query: 627 IAPTFHLNVLKSFIDLFNANSRAVVEK----LNKEAGTFDCHDYMSECTVEILLETAMGV 794
+ P FH N+LK ++ +FN + + K ++ + D +++S T++ L +
Sbjct: 151 LTPAFHFNILKPYMKIFNESVNIMHAKWQLLASEGSARLDMFEHISLMTLDSLQKCVFSF 210
Query: 795 SKTTQDQ 815
Q++
Sbjct: 211 DSHCQEK 217
>AB002461-1|BAA25991.1| 520|Homo sapiens leukotriene B4
omega-hydroxylase protein.
Length = 520
Score = 79.0 bits (186), Expect = 4e-14
Identities = 38/127 (29%), Positives = 70/127 (55%), Gaps = 7/127 (5%)
Frame = +3
Query: 456 WIGP-RLLVFLYDPRDVEVILSSHVHIDKADE--YRFFKPWLGNGLLISTGQKWRSHRKL 626
W+GP +V ++ P ++ +L + I D+ Y F KPWLG+GLL+S G+KW HR++
Sbjct: 91 WVGPWHAIVRIFHPTYIKPVLFAPAAIVPKDKVFYSFLKPWLGDGLLLSAGEKWSRHRRM 150
Query: 627 IAPTFHLNVLKSFIDLFNANSRAVVEK----LNKEAGTFDCHDYMSECTVEILLETAMGV 794
+ P FH N+LK ++ +FN + + K ++ + D +++S T++ L +
Sbjct: 151 LTPAFHFNILKPYMKIFNESVNIMHAKWQLLASEGSARLDMFEHISLMTLDSLQKCVFSF 210
Query: 795 SKTTQDQ 815
Q++
Sbjct: 211 DSHCQEK 217
>AB002454-1|BAA25990.1| 520|Homo sapiens leukotriene B4
omega-hydroxylase protein.
Length = 520
Score = 79.0 bits (186), Expect = 4e-14
Identities = 38/127 (29%), Positives = 70/127 (55%), Gaps = 7/127 (5%)
Frame = +3
Query: 456 WIGP-RLLVFLYDPRDVEVILSSHVHIDKADE--YRFFKPWLGNGLLISTGQKWRSHRKL 626
W+GP +V ++ P ++ +L + I D+ Y F KPWLG+GLL+S G+KW HR++
Sbjct: 91 WVGPWHAIVRIFHPTYIKPVLFAPAAIVPKDKVFYSFLKPWLGDGLLLSAGEKWSRHRRM 150
Query: 627 IAPTFHLNVLKSFIDLFNANSRAVVEK----LNKEAGTFDCHDYMSECTVEILLETAMGV 794
+ P FH N+LK ++ +FN + + K ++ + D +++S T++ L +
Sbjct: 151 LTPAFHFNILKPYMKIFNESVNIMHAKWQLLASEGSARLDMFEHISLMTLDSLQKCVFSF 210
Query: 795 SKTTQDQ 815
Q++
Sbjct: 211 DSHCQEK 217
>AF133298-1|AAD49566.1| 520|Homo sapiens cytochrome P450 protein.
Length = 520
Score = 77.4 bits (182), Expect = 1e-13
Identities = 42/127 (33%), Positives = 70/127 (55%), Gaps = 7/127 (5%)
Frame = +3
Query: 456 WIGPRL-LVFLYDPRDVEVILSSHVHIDKADE--YRFFKPWLGNGLLISTGQKWRSHRKL 626
W+GP ++ L P V ++++ I D Y+ KPWLG+GLL+S G KWR HR+L
Sbjct: 91 WLGPITPIINLCHPDIVRSVINTSDAITDKDIVFYKTLKPWLGDGLLLSVGDKWRHHRRL 150
Query: 627 IAPTFHLNVLKSFIDLFNANS---RAVVEKLNKEAGT-FDCHDYMSECTVEILLETAMGV 794
+ P FH N+LK +I +F+ ++ A ++L E T D +++S T++ L +
Sbjct: 151 LTPAFHFNILKPYIKIFSKSANIMHAKWQRLAMEGSTCLDVFEHISLMTLDSLQKCIFSF 210
Query: 795 SKTTQDQ 815
Q++
Sbjct: 211 DSNCQEK 217
>U02388-1|AAC50052.2| 520|Homo sapiens cytochrome P450 4F2 protein.
Length = 520
Score = 77.0 bits (181), Expect = 2e-13
Identities = 38/129 (29%), Positives = 70/129 (54%), Gaps = 7/129 (5%)
Frame = +3
Query: 450 KIWIGP-RLLVFLYDPRDVEVILSSHVHIDKADE--YRFFKPWLGNGLLISTGQKWRSHR 620
K+W+GP L+ L P + ++++ I D+ Y F +PWLG+GLL+S G KW HR
Sbjct: 89 KVWMGPISPLLSLCHPDIIRSVINASAAIAPKDKFFYSFLEPWLGDGLLLSAGDKWSRHR 148
Query: 621 KLIAPTFHLNVLKSFIDLFNANSRAVVEK----LNKEAGTFDCHDYMSECTVEILLETAM 788
+++ P FH N+LK ++ +FN + + K ++ + D +++S T++ L +
Sbjct: 149 RMLTPAFHFNILKPYMKIFNESVNIMHAKWQLLASEGSACLDMFEHISLMTLDSLQKCVF 208
Query: 789 GVSKTTQDQ 815
Q++
Sbjct: 209 SFDSHCQEK 217
>D26480-1|BAA05490.1| 520|Homo sapiens leukotriene B4
omega-hydroxylase protein.
Length = 520
Score = 77.0 bits (181), Expect = 2e-13
Identities = 38/129 (29%), Positives = 70/129 (54%), Gaps = 7/129 (5%)
Frame = +3
Query: 450 KIWIGP-RLLVFLYDPRDVEVILSSHVHIDKADE--YRFFKPWLGNGLLISTGQKWRSHR 620
K+W+GP L+ L P + ++++ I D+ Y F +PWLG+GLL+S G KW HR
Sbjct: 89 KVWMGPISPLLSLCHPDIIRSVINASAAIAPKDKFFYSFLEPWLGDGLLLSAGDKWSRHR 148
Query: 621 KLIAPTFHLNVLKSFIDLFNANSRAVVEK----LNKEAGTFDCHDYMSECTVEILLETAM 788
+++ P FH N+LK ++ +FN + + K ++ + D +++S T++ L +
Sbjct: 149 RMLTPAFHFNILKPYMKIFNESVNIMHAKWQLLASEGSACLDMFEHISLMTLDSLQKCVF 208
Query: 789 GVSKTTQDQ 815
Q++
Sbjct: 209 SFDSHCQEK 217
>BC067439-1|AAH67439.1| 520|Homo sapiens cytochrome P450, family 4,
subfamily F, polypeptide 2 protein.
Length = 520
Score = 77.0 bits (181), Expect = 2e-13
Identities = 38/129 (29%), Positives = 70/129 (54%), Gaps = 7/129 (5%)
Frame = +3
Query: 450 KIWIGP-RLLVFLYDPRDVEVILSSHVHIDKADE--YRFFKPWLGNGLLISTGQKWRSHR 620
K+W+GP L+ L P + ++++ I D+ Y F +PWLG+GLL+S G KW HR
Sbjct: 89 KVWMGPISPLLSLCHPDIIRSVINASAAIAPKDKFFYSFLEPWLGDGLLLSAGDKWSRHR 148
Query: 621 KLIAPTFHLNVLKSFIDLFNANSRAVVEK----LNKEAGTFDCHDYMSECTVEILLETAM 788
+++ P FH N+LK ++ +FN + + K ++ + D +++S T++ L +
Sbjct: 149 RMLTPAFHFNILKPYMKIFNESVNIMHAKWQLLASEGSACLDMFEHISLMTLDSLQKCVF 208
Query: 789 GVSKTTQDQ 815
Q++
Sbjct: 209 SFDSHCQEK 217
>BC067437-1|AAH67437.1| 520|Homo sapiens cytochrome P450, family 4,
subfamily F, polypeptide 2 protein.
Length = 520
Score = 77.0 bits (181), Expect = 2e-13
Identities = 38/129 (29%), Positives = 70/129 (54%), Gaps = 7/129 (5%)
Frame = +3
Query: 450 KIWIGP-RLLVFLYDPRDVEVILSSHVHIDKADE--YRFFKPWLGNGLLISTGQKWRSHR 620
K+W+GP L+ L P + ++++ I D+ Y F +PWLG+GLL+S G KW HR
Sbjct: 89 KVWMGPISPLLSLCHPDIIRSVINASAAIAPKDKFFYSFLEPWLGDGLLLSAGDKWSRHR 148
Query: 621 KLIAPTFHLNVLKSFIDLFNANSRAVVEK----LNKEAGTFDCHDYMSECTVEILLETAM 788
+++ P FH N+LK ++ +FN + + K ++ + D +++S T++ L +
Sbjct: 149 RMLTPAFHFNILKPYMKIFNESVNIMHAKWQLLASEGSACLDMFEHISLMTLDSLQKCVF 208
Query: 789 GVSKTTQDQ 815
Q++
Sbjct: 209 SFDSHCQEK 217
>AF467894-1|AAL67578.1| 520|Homo sapiens cytochrome P450, subfamily
IVF, polypeptide 2 protein.
Length = 520
Score = 77.0 bits (181), Expect = 2e-13
Identities = 38/129 (29%), Positives = 70/129 (54%), Gaps = 7/129 (5%)
Frame = +3
Query: 450 KIWIGP-RLLVFLYDPRDVEVILSSHVHIDKADE--YRFFKPWLGNGLLISTGQKWRSHR 620
K+W+GP L+ L P + ++++ I D+ Y F +PWLG+GLL+S G KW HR
Sbjct: 89 KVWMGPISPLLSLCHPDIIRSVINASAAIAPKDKFFYSFLEPWLGDGLLLSAGDKWSRHR 148
Query: 621 KLIAPTFHLNVLKSFIDLFNANSRAVVEK----LNKEAGTFDCHDYMSECTVEILLETAM 788
+++ P FH N+LK ++ +FN + + K ++ + D +++S T++ L +
Sbjct: 149 RMLTPAFHFNILKPYMKIFNESVNIMHAKWQLLASEGSACLDMFEHISLMTLDSLQKCVF 208
Query: 789 GVSKTTQDQ 815
Q++
Sbjct: 209 SFDSHCQEK 217
>AC005336-1|AAC27730.1| 520|Homo sapiens CYP4F2 protein.
Length = 520
Score = 77.0 bits (181), Expect = 2e-13
Identities = 38/129 (29%), Positives = 70/129 (54%), Gaps = 7/129 (5%)
Frame = +3
Query: 450 KIWIGP-RLLVFLYDPRDVEVILSSHVHIDKADE--YRFFKPWLGNGLLISTGQKWRSHR 620
K+W+GP L+ L P + ++++ I D+ Y F +PWLG+GLL+S G KW HR
Sbjct: 89 KVWMGPISPLLSLCHPDIIRSVINASAAIAPKDKFFYSFLEPWLGDGLLLSAGDKWSRHR 148
Query: 621 KLIAPTFHLNVLKSFIDLFNANSRAVVEK----LNKEAGTFDCHDYMSECTVEILLETAM 788
+++ P FH N+LK ++ +FN + + K ++ + D +++S T++ L +
Sbjct: 149 RMLTPAFHFNILKPYMKIFNESVNIMHAKWQLLASEGSACLDMFEHISLMTLDSLQKCVF 208
Query: 789 GVSKTTQDQ 815
Q++
Sbjct: 209 SFDSHCQEK 217
>AB015306-1|BAA75823.1| 520|Homo sapiens Leukotriene B4
omega-hydroxylase protein.
Length = 520
Score = 77.0 bits (181), Expect = 2e-13
Identities = 38/129 (29%), Positives = 70/129 (54%), Gaps = 7/129 (5%)
Frame = +3
Query: 450 KIWIGP-RLLVFLYDPRDVEVILSSHVHIDKADE--YRFFKPWLGNGLLISTGQKWRSHR 620
K+W+GP L+ L P + ++++ I D+ Y F +PWLG+GLL+S G KW HR
Sbjct: 89 KVWMGPISPLLSLCHPDIIRSVINASAAIAPKDKFFYSFLEPWLGDGLLLSAGDKWSRHR 148
Query: 621 KLIAPTFHLNVLKSFIDLFNANSRAVVEK----LNKEAGTFDCHDYMSECTVEILLETAM 788
+++ P FH N+LK ++ +FN + + K ++ + D +++S T++ L +
Sbjct: 149 RMLTPAFHFNILKPYMKIFNESVNIMHAKWQLLASEGSACLDMFEHISLMTLDSLQKCVF 208
Query: 789 GVSKTTQDQ 815
Q++
Sbjct: 209 SFDSHCQEK 217
>BC067440-1|AAH67440.1| 520|Homo sapiens cytochrome P450, family 4,
subfamily F, polypeptide 2 protein.
Length = 520
Score = 76.6 bits (180), Expect = 2e-13
Identities = 38/129 (29%), Positives = 70/129 (54%), Gaps = 7/129 (5%)
Frame = +3
Query: 450 KIWIGP-RLLVFLYDPRDVEVILSSHVHIDKADE--YRFFKPWLGNGLLISTGQKWRSHR 620
K+W+GP L+ L P + ++++ I D+ Y F +PWLG+GLL+S G KW HR
Sbjct: 89 KVWMGPISPLLSLCHPDIIRSVINASAAIAPKDKFFYSFLEPWLGDGLLLSAGDKWSRHR 148
Query: 621 KLIAPTFHLNVLKSFIDLFNANSRAVVEK----LNKEAGTFDCHDYMSECTVEILLETAM 788
+++ P FH N+LK ++ +FN + + K ++ + D +++S T++ L +
Sbjct: 149 RMLTPAFHFNILKPYMKIFNDSVNIMHAKWQLLASEGSACLDMFEHISLMTLDSLQKCVF 208
Query: 789 GVSKTTQDQ 815
Q++
Sbjct: 209 SFDSHCQEK 217
>AF221943-1|AAF86378.1| 175|Homo sapiens leukotriene B4 omega
hydroxylase protein.
Length = 175
Score = 76.2 bits (179), Expect = 3e-13
Identities = 32/80 (40%), Positives = 51/80 (63%), Gaps = 3/80 (3%)
Frame = +3
Query: 450 KIWIGP-RLLVFLYDPRDVEVILSSHVHIDKADE--YRFFKPWLGNGLLISTGQKWRSHR 620
K+W+GP L+ L P + ++++ I D+ Y F +PWLG+GLL+S G KW HR
Sbjct: 89 KVWMGPISPLLSLCHPDIIRSVINASAAIAPKDKFFYSFLEPWLGDGLLLSAGDKWSRHR 148
Query: 621 KLIAPTFHLNVLKSFIDLFN 680
+++ P FH N+LK ++ +FN
Sbjct: 149 RMLTPAFHFNILKPYMKIFN 168
>J02871-1|AAA35712.1| 511|Homo sapiens protein ( Human lung
cytochrome P450 (IV subfamily) BI protein, complete cds.
).
Length = 511
Score = 75.8 bits (178), Expect = 4e-13
Identities = 58/207 (28%), Positives = 98/207 (47%), Gaps = 7/207 (3%)
Frame = +3
Query: 204 VVPS--NSTFSAINLFYVLLVPAV-ILWYTYWRMSRRRLYELAEKLNGPKGLPLIGNALE 374
+VPS + +FS++ L+ L+ + L + + RR L + +K GP L G+ALE
Sbjct: 1 MVPSFLSLSFSSLGLWASGLILVLGFLKLIHLLLRRRTLAKAMDKFPGPPTHWLFGHALE 60
Query: 375 FVGGSAEIFSNIIQKSLAFDNESVVKIWIGPRL-LVFLYDPRDVEVILSSHVHIDKADEY 551
+ ++ S A +W G + + +Y+P D + S D Y
Sbjct: 61 IQETGS--LDKVV--SWAHQFPYAHPLWFGQFIGFLNIYEP-DYAKAVYSRGDPKAPDVY 115
Query: 552 RFFKPWLGNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVEKLN---KEA 722
FF W+G GLL+ G KW HRKL+ P FH +VLK ++ +F ++R +++K +E
Sbjct: 116 DFFLQWIGRGLLVLEGPKWLQHRKLLTPGFHYDVLKPYVAVFTESTRIMLDKWEEKAREG 175
Query: 723 GTFDCHDYMSECTVEILLETAMGVSKT 803
+FD + + L++ G T
Sbjct: 176 KSFDIFCDVGHMALNTLMKCTFGRGDT 202
>X16699-1|CAA34672.1| 511|Homo sapiens protein ( Human mRNA for
cytochrome P-450HP. ).
Length = 511
Score = 74.1 bits (174), Expect = 1e-12
Identities = 57/207 (27%), Positives = 98/207 (47%), Gaps = 7/207 (3%)
Frame = +3
Query: 204 VVPS--NSTFSAINLFYVLLVPAV-ILWYTYWRMSRRRLYELAEKLNGPKGLPLIGNALE 374
+VPS + +FS++ L+ L+ + L + + R+ L + +K GP L G+ALE
Sbjct: 1 MVPSFLSLSFSSLGLWASGLILVLGFLKLIHLLLRRQTLAKAMDKFPGPPTHWLFGHALE 60
Query: 375 FVGGSAEIFSNIIQKSLAFDNESVVKIWIGPRL-LVFLYDPRDVEVILSSHVHIDKADEY 551
+ ++ S A +W G + + +Y+P D + S D Y
Sbjct: 61 IQETGS--LDKVV--SWAHQFPYAHPLWFGQFIGFLNIYEP-DYAKAVYSRGDPKAPDVY 115
Query: 552 RFFKPWLGNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVEKLN---KEA 722
FF W+G GLL+ G KW HRKL+ P FH +VLK ++ +F ++R +++K +E
Sbjct: 116 DFFLQWIGRGLLVLEGPKWLQHRKLLTPGFHYDVLKPYVAVFTESTRIMLDKWEEKAREG 175
Query: 723 GTFDCHDYMSECTVEILLETAMGVSKT 803
+FD + + L++ G T
Sbjct: 176 KSFDIFCDVGHMALNTLMKCTFGRGDT 202
>DQ518907-1|ABF47106.1| 511|Homo sapiens cytochrome P450, family 4,
subfamily B, polypeptide 1 protein.
Length = 511
Score = 74.1 bits (174), Expect = 1e-12
Identities = 57/207 (27%), Positives = 98/207 (47%), Gaps = 7/207 (3%)
Frame = +3
Query: 204 VVPS--NSTFSAINLFYVLLVPAV-ILWYTYWRMSRRRLYELAEKLNGPKGLPLIGNALE 374
+VPS + +FS++ L+ L+ + L + + R+ L + +K GP L G+ALE
Sbjct: 1 MVPSFLSLSFSSLGLWASGLILVLGFLKLIHLLLRRQTLAKAMDKFPGPPTHWLFGHALE 60
Query: 375 FVGGSAEIFSNIIQKSLAFDNESVVKIWIGPRL-LVFLYDPRDVEVILSSHVHIDKADEY 551
+ ++ S A +W G + + +Y+P D + S D Y
Sbjct: 61 IQETGS--LDKVV--SWAHQFPYAHPLWFGQFIGFLNIYEP-DYAKAVYSRGDPKAPDVY 115
Query: 552 RFFKPWLGNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVEKLN---KEA 722
FF W+G GLL+ G KW HRKL+ P FH +VLK ++ +F ++R +++K +E
Sbjct: 116 DFFLQWIGRGLLVLEGPKWLQHRKLLTPGFHYDVLKPYVAVFTESTRIMLDKWEEKAREG 175
Query: 723 GTFDCHDYMSECTVEILLETAMGVSKT 803
+FD + + L++ G T
Sbjct: 176 KSFDIFCDVGHMALNTLMKCTFGRGDT 202
>BC017758-1|AAH17758.1| 512|Homo sapiens cytochrome P450, family 4,
subfamily B, polypeptide 1 protein.
Length = 512
Score = 74.1 bits (174), Expect = 1e-12
Identities = 57/207 (27%), Positives = 98/207 (47%), Gaps = 7/207 (3%)
Frame = +3
Query: 204 VVPS--NSTFSAINLFYVLLVPAV-ILWYTYWRMSRRRLYELAEKLNGPKGLPLIGNALE 374
+VPS + +FS++ L+ L+ + L + + R+ L + +K GP L G+ALE
Sbjct: 1 MVPSFLSLSFSSLGLWASGLILVLGFLKLIHLLLRRQTLAKAMDKFPGPPTHWLFGHALE 60
Query: 375 FVGGSAEIFSNIIQKSLAFDNESVVKIWIGPRL-LVFLYDPRDVEVILSSHVHIDKADEY 551
+ ++ S A +W G + + +Y+P D + S D Y
Sbjct: 61 IQETGS--LDKVV--SWAHQFPYAHPLWFGQFIGFLNIYEP-DYAKAVYSRGDPKAPDVY 115
Query: 552 RFFKPWLGNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVEKLN---KEA 722
FF W+G GLL+ G KW HRKL+ P FH +VLK ++ +F ++R +++K +E
Sbjct: 116 DFFLQWIGRGLLVLEGPKWLQHRKLLTPGFHYDVLKPYVAVFTESTRIMLDKWEEKAREG 175
Query: 723 GTFDCHDYMSECTVEILLETAMGVSKT 803
+FD + + L++ G T
Sbjct: 176 KSFDIFCDVGHMALNTLMKCTFGRGDT 202
>AY151048-1|AAN72311.1| 512|Homo sapiens pulmonary cytochrome P450
4B1 protein.
Length = 512
Score = 74.1 bits (174), Expect = 1e-12
Identities = 57/207 (27%), Positives = 98/207 (47%), Gaps = 7/207 (3%)
Frame = +3
Query: 204 VVPS--NSTFSAINLFYVLLVPAV-ILWYTYWRMSRRRLYELAEKLNGPKGLPLIGNALE 374
+VPS + +FS++ L+ L+ + L + + R+ L + +K GP L G+ALE
Sbjct: 1 MVPSFLSLSFSSLGLWASGLILVLGFLKLIHLLLRRQTLAKAMDKFPGPPTHWLFGHALE 60
Query: 375 FVGGSAEIFSNIIQKSLAFDNESVVKIWIGPRL-LVFLYDPRDVEVILSSHVHIDKADEY 551
+ ++ S A +W G + + +Y+P D + S D Y
Sbjct: 61 IQETGS--LDKVV--SWAHQFPYAHPLWFGQFIGFLNIYEP-DYAKAVYSRGDPKAPDVY 115
Query: 552 RFFKPWLGNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVEKLN---KEA 722
FF W+G GLL+ G KW HRKL+ P FH +VLK ++ +F ++R +++K +E
Sbjct: 116 DFFLQWIGRGLLVLEGPKWLQHRKLLTPGFHYDVLKPYVAVFTESTRIMLDKWEEKAREG 175
Query: 723 GTFDCHDYMSECTVEILLETAMGVSKT 803
+FD + + L++ G T
Sbjct: 176 KSFDIFCDVGHMALNTLMKCTFGRGDT 202
>AY064486-1|AAL57721.1| 511|Homo sapiens cytochrome P450 protein.
Length = 511
Score = 74.1 bits (174), Expect = 1e-12
Identities = 57/207 (27%), Positives = 98/207 (47%), Gaps = 7/207 (3%)
Frame = +3
Query: 204 VVPS--NSTFSAINLFYVLLVPAV-ILWYTYWRMSRRRLYELAEKLNGPKGLPLIGNALE 374
+VPS + +FS++ L+ L+ + L + + R+ L + +K GP L G+ALE
Sbjct: 1 MVPSFLSLSFSSLGLWASGLILVLGFLKLIHLLLRRQTLAKAMDKFPGPPTHWLFGHALE 60
Query: 375 FVGGSAEIFSNIIQKSLAFDNESVVKIWIGPRL-LVFLYDPRDVEVILSSHVHIDKADEY 551
+ ++ S A +W G + + +Y+P D + S D Y
Sbjct: 61 IQETGS--LDKVV--SWAHQFPYAHPLWFGQFIGFLNIYEP-DYAKAVYSRGDPKAPDVY 115
Query: 552 RFFKPWLGNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVEKLN---KEA 722
FF W+G GLL+ G KW HRKL+ P FH +VLK ++ +F ++R +++K +E
Sbjct: 116 DFFLQWIGRGLLVLEGPKWLQHRKLLTPGFHYDVLKPYVAVFTESTRIMLDKWEEKAREG 175
Query: 723 GTFDCHDYMSECTVEILLETAMGVSKT 803
+FD + + L++ G T
Sbjct: 176 KSFDIFCDVGHMALNTLMKCTFGRGDT 202
>AY064484-1|AAL57719.1| 295|Homo sapiens truncated cytochrome P450
protein.
Length = 295
Score = 74.1 bits (174), Expect = 1e-12
Identities = 57/207 (27%), Positives = 98/207 (47%), Gaps = 7/207 (3%)
Frame = +3
Query: 204 VVPS--NSTFSAINLFYVLLVPAV-ILWYTYWRMSRRRLYELAEKLNGPKGLPLIGNALE 374
+VPS + +FS++ L+ L+ + L + + R+ L + +K GP L G+ALE
Sbjct: 1 MVPSFLSLSFSSLGLWASGLILVLGFLKLIHLLLRRQTLAKAMDKFPGPPTHWLFGHALE 60
Query: 375 FVGGSAEIFSNIIQKSLAFDNESVVKIWIGPRL-LVFLYDPRDVEVILSSHVHIDKADEY 551
+ ++ S A +W G + + +Y+P D + S D Y
Sbjct: 61 IQETGS--LDKVV--SWAHQFPYAHPLWFGQFIGFLNIYEP-DYAKAVYSRGDPKAPDVY 115
Query: 552 RFFKPWLGNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVEKLN---KEA 722
FF W+G GLL+ G KW HRKL+ P FH +VLK ++ +F ++R +++K +E
Sbjct: 116 DFFLQWIGRGLLVLEGPKWLQHRKLLTPGFHYDVLKPYVAVFTESTRIMLDKWEEKAREG 175
Query: 723 GTFDCHDYMSECTVEILLETAMGVSKT 803
+FD + + L++ G T
Sbjct: 176 KSFDIFCDVGHMALNTLMKCTFGRGDT 202
>AL593856-7|CAI16982.1| 512|Homo sapiens cytochrome P450, family 4,
subfamily B, polypeptide 1 protein.
Length = 512
Score = 74.1 bits (174), Expect = 1e-12
Identities = 57/207 (27%), Positives = 98/207 (47%), Gaps = 7/207 (3%)
Frame = +3
Query: 204 VVPS--NSTFSAINLFYVLLVPAV-ILWYTYWRMSRRRLYELAEKLNGPKGLPLIGNALE 374
+VPS + +FS++ L+ L+ + L + + R+ L + +K GP L G+ALE
Sbjct: 1 MVPSFLSLSFSSLGLWASGLILVLGFLKLIHLLLRRQTLAKAMDKFPGPPTHWLFGHALE 60
Query: 375 FVGGSAEIFSNIIQKSLAFDNESVVKIWIGPRL-LVFLYDPRDVEVILSSHVHIDKADEY 551
+ ++ S A +W G + + +Y+P D + S D Y
Sbjct: 61 IQETGS--LDKVV--SWAHQFPYAHPLWFGQFIGFLNIYEP-DYAKAVYSRGDPKAPDVY 115
Query: 552 RFFKPWLGNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVEKLN---KEA 722
FF W+G GLL+ G KW HRKL+ P FH +VLK ++ +F ++R +++K +E
Sbjct: 116 DFFLQWIGRGLLVLEGPKWLQHRKLLTPGFHYDVLKPYVAVFTESTRIMLDKWEEKAREG 175
Query: 723 GTFDCHDYMSECTVEILLETAMGVSKT 803
+FD + + L++ G T
Sbjct: 176 KSFDIFCDVGHMALNTLMKCTFGRGDT 202
>AL593856-6|CAI16981.1| 511|Homo sapiens cytochrome P450, family 4,
subfamily B, polypeptide 1 protein.
Length = 511
Score = 74.1 bits (174), Expect = 1e-12
Identities = 57/207 (27%), Positives = 98/207 (47%), Gaps = 7/207 (3%)
Frame = +3
Query: 204 VVPS--NSTFSAINLFYVLLVPAV-ILWYTYWRMSRRRLYELAEKLNGPKGLPLIGNALE 374
+VPS + +FS++ L+ L+ + L + + R+ L + +K GP L G+ALE
Sbjct: 1 MVPSFLSLSFSSLGLWASGLILVLGFLKLIHLLLRRQTLAKAMDKFPGPPTHWLFGHALE 60
Query: 375 FVGGSAEIFSNIIQKSLAFDNESVVKIWIGPRL-LVFLYDPRDVEVILSSHVHIDKADEY 551
+ ++ S A +W G + + +Y+P D + S D Y
Sbjct: 61 IQETGS--LDKVV--SWAHQFPYAHPLWFGQFIGFLNIYEP-DYAKAVYSRGDPKAPDVY 115
Query: 552 RFFKPWLGNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVEKLN---KEA 722
FF W+G GLL+ G KW HRKL+ P FH +VLK ++ +F ++R +++K +E
Sbjct: 116 DFFLQWIGRGLLVLEGPKWLQHRKLLTPGFHYDVLKPYVAVFTESTRIMLDKWEEKAREG 175
Query: 723 GTFDCHDYMSECTVEILLETAMGVSKT 803
+FD + + L++ G T
Sbjct: 176 KSFDIFCDVGHMALNTLMKCTFGRGDT 202
>AL356793-4|CAI22557.1| 512|Homo sapiens cytochrome P450, family 4,
subfamily B, polypeptide 1 protein.
Length = 512
Score = 74.1 bits (174), Expect = 1e-12
Identities = 57/207 (27%), Positives = 98/207 (47%), Gaps = 7/207 (3%)
Frame = +3
Query: 204 VVPS--NSTFSAINLFYVLLVPAV-ILWYTYWRMSRRRLYELAEKLNGPKGLPLIGNALE 374
+VPS + +FS++ L+ L+ + L + + R+ L + +K GP L G+ALE
Sbjct: 1 MVPSFLSLSFSSLGLWASGLILVLGFLKLIHLLLRRQTLAKAMDKFPGPPTHWLFGHALE 60
Query: 375 FVGGSAEIFSNIIQKSLAFDNESVVKIWIGPRL-LVFLYDPRDVEVILSSHVHIDKADEY 551
+ ++ S A +W G + + +Y+P D + S D Y
Sbjct: 61 IQETGS--LDKVV--SWAHQFPYAHPLWFGQFIGFLNIYEP-DYAKAVYSRGDPKAPDVY 115
Query: 552 RFFKPWLGNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVEKLN---KEA 722
FF W+G GLL+ G KW HRKL+ P FH +VLK ++ +F ++R +++K +E
Sbjct: 116 DFFLQWIGRGLLVLEGPKWLQHRKLLTPGFHYDVLKPYVAVFTESTRIMLDKWEEKAREG 175
Query: 723 GTFDCHDYMSECTVEILLETAMGVSKT 803
+FD + + L++ G T
Sbjct: 176 KSFDIFCDVGHMALNTLMKCTFGRGDT 202
>AL356793-3|CAI22559.1| 511|Homo sapiens cytochrome P450, family 4,
subfamily B, polypeptide 1 protein.
Length = 511
Score = 74.1 bits (174), Expect = 1e-12
Identities = 57/207 (27%), Positives = 98/207 (47%), Gaps = 7/207 (3%)
Frame = +3
Query: 204 VVPS--NSTFSAINLFYVLLVPAV-ILWYTYWRMSRRRLYELAEKLNGPKGLPLIGNALE 374
+VPS + +FS++ L+ L+ + L + + R+ L + +K GP L G+ALE
Sbjct: 1 MVPSFLSLSFSSLGLWASGLILVLGFLKLIHLLLRRQTLAKAMDKFPGPPTHWLFGHALE 60
Query: 375 FVGGSAEIFSNIIQKSLAFDNESVVKIWIGPRL-LVFLYDPRDVEVILSSHVHIDKADEY 551
+ ++ S A +W G + + +Y+P D + S D Y
Sbjct: 61 IQETGS--LDKVV--SWAHQFPYAHPLWFGQFIGFLNIYEP-DYAKAVYSRGDPKAPDVY 115
Query: 552 RFFKPWLGNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVEKLN---KEA 722
FF W+G GLL+ G KW HRKL+ P FH +VLK ++ +F ++R +++K +E
Sbjct: 116 DFFLQWIGRGLLVLEGPKWLQHRKLLTPGFHYDVLKPYVAVFTESTRIMLDKWEEKAREG 175
Query: 723 GTFDCHDYMSECTVEILLETAMGVSKT 803
+FD + + L++ G T
Sbjct: 176 KSFDIFCDVGHMALNTLMKCTFGRGDT 202
>AF491285-1|AAM09532.1| 511|Homo sapiens cytochrome P450 protein.
Length = 511
Score = 74.1 bits (174), Expect = 1e-12
Identities = 57/207 (27%), Positives = 98/207 (47%), Gaps = 7/207 (3%)
Frame = +3
Query: 204 VVPS--NSTFSAINLFYVLLVPAV-ILWYTYWRMSRRRLYELAEKLNGPKGLPLIGNALE 374
+VPS + +FS++ L+ L+ + L + + R+ L + +K GP L G+ALE
Sbjct: 1 MVPSFLSLSFSSLGLWASGLILVLGFLKLIHLLLRRQTLAKAMDKFPGPPTHWLFGHALE 60
Query: 375 FVGGSAEIFSNIIQKSLAFDNESVVKIWIGPRL-LVFLYDPRDVEVILSSHVHIDKADEY 551
+ ++ S A +W G + + +Y+P D + S D Y
Sbjct: 61 IQETGS--LDKVV--SWAHQFPYAHPLWFGQFIGFLNIYEP-DYAKAVYSRGDPKAPDVY 115
Query: 552 RFFKPWLGNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVEKLN---KEA 722
FF W+G GLL+ G KW HRKL+ P FH +VLK ++ +F ++R +++K +E
Sbjct: 116 DFFLQWIGRGLLVLEGPKWLQHRKLLTPGFHYDVLKPYVAVFTESTRIMLDKWEEKAREG 175
Query: 723 GTFDCHDYMSECTVEILLETAMGVSKT 803
+FD + + L++ G T
Sbjct: 176 KSFDIFCDVGHMALNTLMKCTFGRGDT 202
>AY064485-1|AAL57720.1| 511|Homo sapiens cytochrome P450 protein.
Length = 511
Score = 73.7 bits (173), Expect = 1e-12
Identities = 57/207 (27%), Positives = 98/207 (47%), Gaps = 7/207 (3%)
Frame = +3
Query: 204 VVPS--NSTFSAINLFYVLLVPAV-ILWYTYWRMSRRRLYELAEKLNGPKGLPLIGNALE 374
+VPS + +FS++ L+ L+ + L + + R+ L + +K GP L G+ALE
Sbjct: 1 MVPSFLSLSFSSLGLWASGLILVLGFLKLIHLLLRRQTLAKAMDKFPGPPTHWLFGHALE 60
Query: 375 FVGGSAEIFSNIIQKSLAFDNESVVKIWIGPRL-LVFLYDPRDVEVILSSHVHIDKADEY 551
+ ++ S A +W G + + +Y+P D + S D Y
Sbjct: 61 IQETGS--LDKVV--SWAHQFPYAHPLWFGQFIGFLNIYEP-DYAKAVYSRGDPKAPDVY 115
Query: 552 RFFKPWLGNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVEKLNK---EA 722
FF W+G GLL+ G KW HRKL+ P FH +VLK ++ +F ++R +++K + E
Sbjct: 116 DFFLQWIGRGLLVLEGPKWLQHRKLLTPGFHYDVLKPYVAVFTESTRIMLDKWEEKAWEG 175
Query: 723 GTFDCHDYMSECTVEILLETAMGVSKT 803
+FD + + L++ G T
Sbjct: 176 KSFDIFCDVGHMALNTLMKCTFGRGDT 202
>S67581-1|AAB29503.1| 591|Homo sapiens fatty acid omega-hydroxylase
protein.
Length = 591
Score = 70.5 bits (165), Expect = 1e-11
Identities = 36/114 (31%), Positives = 63/114 (55%), Gaps = 4/114 (3%)
Frame = +3
Query: 456 WI-GPRLLVFLYDPRDVEVILSSHVHIDKADEYRFFKPWLGNGLLISTGQKWRSHRKLIA 632
W+ G ++ V LYDP ++VIL YRF PW+G GLL+ GQ W HR+++
Sbjct: 89 WLWGGKVRVQLYDPDYMKVILGRS-DPKSHGSYRFLAPWIGYGLLLLNGQTWFQHRRMLT 147
Query: 633 PTFHLNVLKSFIDLFNANSRAVVEKLNKEAG---TFDCHDYMSECTVEILLETA 785
P FH ++LK ++ L + R +++K + G + ++S T++ +++ A
Sbjct: 148 PAFHYDILKPYVGLMADSVRVMLDKWEELLGQDSPLEVFQHVSLMTLDTIMKCA 201
>S67580-1|AAB29502.1| 519|Homo sapiens fatty acid omega-hydroxylase
protein.
Length = 519
Score = 70.5 bits (165), Expect = 1e-11
Identities = 36/114 (31%), Positives = 63/114 (55%), Gaps = 4/114 (3%)
Frame = +3
Query: 456 WI-GPRLLVFLYDPRDVEVILSSHVHIDKADEYRFFKPWLGNGLLISTGQKWRSHRKLIA 632
W+ G ++ V LYDP ++VIL YRF PW+G GLL+ GQ W HR+++
Sbjct: 89 WLWGGKVRVQLYDPDYMKVILGRS-DPKSHGSYRFLAPWIGYGLLLLNGQTWFQHRRMLT 147
Query: 633 PTFHLNVLKSFIDLFNANSRAVVEKLNKEAG---TFDCHDYMSECTVEILLETA 785
P FH ++LK ++ L + R +++K + G + ++S T++ +++ A
Sbjct: 148 PAFHYDILKPYVGLMADSVRVMLDKWEELLGQDSPLEVFQHVSLMTLDTIMKCA 201
>L04751-1|AAA58436.1| 519|Homo sapiens cytochrome P450 protein.
Length = 519
Score = 70.5 bits (165), Expect = 1e-11
Identities = 36/114 (31%), Positives = 63/114 (55%), Gaps = 4/114 (3%)
Frame = +3
Query: 456 WI-GPRLLVFLYDPRDVEVILSSHVHIDKADEYRFFKPWLGNGLLISTGQKWRSHRKLIA 632
W+ G ++ V LYDP ++VIL YRF PW+G GLL+ GQ W HR+++
Sbjct: 89 WLWGGKVRVQLYDPDYMKVILGRS-DPKSHGSYRFLAPWIGYGLLLLNGQTWFQHRRMLT 147
Query: 633 PTFHLNVLKSFIDLFNANSRAVVEKLNKEAG---TFDCHDYMSECTVEILLETA 785
P FH ++LK ++ L + R +++K + G + ++S T++ +++ A
Sbjct: 148 PAFHYDILKPYVGLMADSVRVMLDKWEELLGQDSPLEVFQHVSLMTLDTIMKCA 201
>D26481-1|BAA05491.1| 519|Homo sapiens fatty acids
omega-hydroxylase protein.
Length = 519
Score = 70.5 bits (165), Expect = 1e-11
Identities = 36/114 (31%), Positives = 63/114 (55%), Gaps = 4/114 (3%)
Frame = +3
Query: 456 WI-GPRLLVFLYDPRDVEVILSSHVHIDKADEYRFFKPWLGNGLLISTGQKWRSHRKLIA 632
W+ G ++ V LYDP ++VIL YRF PW+G GLL+ GQ W HR+++
Sbjct: 89 WLWGGKVRVQLYDPDYMKVILGRS-DPKSHGSYRFLAPWIGYGLLLLNGQTWFQHRRMLT 147
Query: 633 PTFHLNVLKSFIDLFNANSRAVVEKLNKEAG---TFDCHDYMSECTVEILLETA 785
P FH ++LK ++ L + R +++K + G + ++S T++ +++ A
Sbjct: 148 PAFHYDILKPYVGLMADSVRVMLDKWEELLGQDSPLEVFQHVSLMTLDTIMKCA 201
>D13705-1|BAA02864.1| 521|Homo sapiens fatty acid omega-hydroxylase
protein.
Length = 521
Score = 70.5 bits (165), Expect = 1e-11
Identities = 36/114 (31%), Positives = 63/114 (55%), Gaps = 4/114 (3%)
Frame = +3
Query: 456 WI-GPRLLVFLYDPRDVEVILSSHVHIDKADEYRFFKPWLGNGLLISTGQKWRSHRKLIA 632
W+ G ++ V LYDP ++VIL YRF PW+G GLL+ GQ W HR+++
Sbjct: 89 WLWGGKVRVQLYDPDYMKVILGRS-DPKSHGSYRFLAPWIGYGLLLLNGQTWFQHRRMLT 147
Query: 633 PTFHLNVLKSFIDLFNANSRAVVEKLNKEAG---TFDCHDYMSECTVEILLETA 785
P FH ++LK ++ L + R +++K + G + ++S T++ +++ A
Sbjct: 148 PAFHYDILKPYVGLMADSVRVMLDKWEELLGQDSPLEVFQHVSLMTLDTIMKCA 201
>BC041158-1|AAH41158.1| 455|Homo sapiens CYP4A11 protein protein.
Length = 455
Score = 70.5 bits (165), Expect = 1e-11
Identities = 36/114 (31%), Positives = 63/114 (55%), Gaps = 4/114 (3%)
Frame = +3
Query: 456 WI-GPRLLVFLYDPRDVEVILSSHVHIDKADEYRFFKPWLGNGLLISTGQKWRSHRKLIA 632
W+ G ++ V LYDP ++VIL YRF PW+G GLL+ GQ W HR+++
Sbjct: 89 WLWGGKVRVQLYDPDYMKVILGRS-DPKSHGSYRFLAPWIGYGLLLLNGQTWFQHRRMLT 147
Query: 633 PTFHLNVLKSFIDLFNANSRAVVEKLNKEAG---TFDCHDYMSECTVEILLETA 785
P FH ++LK ++ L + R +++K + G + ++S T++ +++ A
Sbjct: 148 PAFHYDILKPYVGLMADSVRVMLDKWEELLGQDSPLEVFQHVSLMTLDTIMKCA 201
>BC022851-1|AAH22851.1| 215|Homo sapiens CYP4A11 protein protein.
Length = 215
Score = 70.5 bits (165), Expect = 1e-11
Identities = 36/114 (31%), Positives = 63/114 (55%), Gaps = 4/114 (3%)
Frame = +3
Query: 456 WI-GPRLLVFLYDPRDVEVILSSHVHIDKADEYRFFKPWLGNGLLISTGQKWRSHRKLIA 632
W+ G ++ V LYDP ++VIL YRF PW+G GLL+ GQ W HR+++
Sbjct: 89 WLWGGKVRVQLYDPDYMKVILGRS-DPKSHGSYRFLAPWIGYGLLLLNGQTWFQHRRMLT 147
Query: 633 PTFHLNVLKSFIDLFNANSRAVVEKLNKEAG---TFDCHDYMSECTVEILLETA 785
P FH ++LK ++ L + R +++K + G + ++S T++ +++ A
Sbjct: 148 PAFHYDILKPYVGLMADSVRVMLDKWEELLGQDSPLEVFQHVSLMTLDTIMKCA 201
>AY369778-1|AAQ56847.1| 519|Homo sapiens cytochrome P450, family 4,
subfamily A, polypeptide 11 protein.
Length = 519
Score = 70.5 bits (165), Expect = 1e-11
Identities = 36/114 (31%), Positives = 63/114 (55%), Gaps = 4/114 (3%)
Frame = +3
Query: 456 WI-GPRLLVFLYDPRDVEVILSSHVHIDKADEYRFFKPWLGNGLLISTGQKWRSHRKLIA 632
W+ G ++ V LYDP ++VIL YRF PW+G GLL+ GQ W HR+++
Sbjct: 89 WLWGGKVRVQLYDPDYMKVILGRS-DPKSHGSYRFLAPWIGYGLLLLNGQTWFQHRRMLT 147
Query: 633 PTFHLNVLKSFIDLFNANSRAVVEKLNKEAG---TFDCHDYMSECTVEILLETA 785
P FH ++LK ++ L + R +++K + G + ++S T++ +++ A
Sbjct: 148 PAFHYDILKPYVGLMADSVRVMLDKWEELLGQDSPLEVFQHVSLMTLDTIMKCA 201
>AL731892-4|CAH72779.1| 455|Homo sapiens cytochrome P450, family 4,
subfamily A, polypeptide 11 protein.
Length = 455
Score = 70.5 bits (165), Expect = 1e-11
Identities = 36/114 (31%), Positives = 63/114 (55%), Gaps = 4/114 (3%)
Frame = +3
Query: 456 WI-GPRLLVFLYDPRDVEVILSSHVHIDKADEYRFFKPWLGNGLLISTGQKWRSHRKLIA 632
W+ G ++ V LYDP ++VIL YRF PW+G GLL+ GQ W HR+++
Sbjct: 89 WLWGGKVRVQLYDPDYMKVILGRS-DPKSHGSYRFLAPWIGYGLLLLNGQTWFQHRRMLT 147
Query: 633 PTFHLNVLKSFIDLFNANSRAVVEKLNKEAG---TFDCHDYMSECTVEILLETA 785
P FH ++LK ++ L + R +++K + G + ++S T++ +++ A
Sbjct: 148 PAFHYDILKPYVGLMADSVRVMLDKWEELLGQDSPLEVFQHVSLMTLDTIMKCA 201
>AL731892-3|CAH72778.1| 519|Homo sapiens cytochrome P450, family 4,
subfamily A, polypeptide 11 protein.
Length = 519
Score = 70.5 bits (165), Expect = 1e-11
Identities = 36/114 (31%), Positives = 63/114 (55%), Gaps = 4/114 (3%)
Frame = +3
Query: 456 WI-GPRLLVFLYDPRDVEVILSSHVHIDKADEYRFFKPWLGNGLLISTGQKWRSHRKLIA 632
W+ G ++ V LYDP ++VIL YRF PW+G GLL+ GQ W HR+++
Sbjct: 89 WLWGGKVRVQLYDPDYMKVILGRS-DPKSHGSYRFLAPWIGYGLLLLNGQTWFQHRRMLT 147
Query: 633 PTFHLNVLKSFIDLFNANSRAVVEKLNKEAG---TFDCHDYMSECTVEILLETA 785
P FH ++LK ++ L + R +++K + G + ++S T++ +++ A
Sbjct: 148 PAFHYDILKPYVGLMADSVRVMLDKWEELLGQDSPLEVFQHVSLMTLDTIMKCA 201
>AF525488-1|AAO16078.1| 519|Homo sapiens cytochrome P450, subfamily
IVA, polypeptide 11 protein.
Length = 519
Score = 70.5 bits (165), Expect = 1e-11
Identities = 36/114 (31%), Positives = 63/114 (55%), Gaps = 4/114 (3%)
Frame = +3
Query: 456 WI-GPRLLVFLYDPRDVEVILSSHVHIDKADEYRFFKPWLGNGLLISTGQKWRSHRKLIA 632
W+ G ++ V LYDP ++VIL YRF PW+G GLL+ GQ W HR+++
Sbjct: 89 WLWGGKVRVQLYDPDYMKVILGRS-DPKSHGSYRFLAPWIGYGLLLLNGQTWFQHRRMLT 147
Query: 633 PTFHLNVLKSFIDLFNANSRAVVEKLNKEAG---TFDCHDYMSECTVEILLETA 785
P FH ++LK ++ L + R +++K + G + ++S T++ +++ A
Sbjct: 148 PAFHYDILKPYVGLMADSVRVMLDKWEELLGQDSPLEVFQHVSLMTLDTIMKCA 201
>AY280372-1|AAQ21368.1| 519|Homo sapiens cytochrome P450 4A22
protein.
Length = 519
Score = 69.7 bits (163), Expect = 2e-11
Identities = 48/189 (25%), Positives = 92/189 (48%), Gaps = 3/189 (1%)
Frame = +3
Query: 228 SAINLFYVLLVPAVILWYTYWRMSRRRLYELAEKLNGPKGLPLIGNALEFVGGSAEIFSN 407
+++ + +LL+ A L+ + R+ L + ++ P L G+ EF
Sbjct: 22 TSLLILLLLLIKAAQLY-----LHRQWLLKALQQFPCPPSHWLFGHIQEFQHDQE--LQR 74
Query: 408 IIQKSLAFDNESVVKIWIGPRLLVFLYDPRDVEVILSSHVHIDKADEYRFFKPWLGNGLL 587
I ++ F + IW G ++ V LYDP ++VIL Y+F PW+G LL
Sbjct: 75 IQERVKTFPSACPYWIW-GGKVRVQLYDPDYMKVILGRS-DSKSHGSYKFLAPWIGYSLL 132
Query: 588 ISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVEKLNKEAG---TFDCHDYMSEC 758
+ GQ W HR+++ P FH ++LK ++ L + R +++K + G + ++S
Sbjct: 133 LLNGQTWFQHRRMLTPAFHYDILKPYVGLMADSVRVMLDKWEELLGQDSPLEFFQHVSLM 192
Query: 759 TVEILLETA 785
T++ ++++A
Sbjct: 193 TLDTIMKSA 201
>BC142607-1|AAI42608.1| 455|Homo sapiens CYP4A22 protein protein.
Length = 455
Score = 69.3 bits (162), Expect = 3e-11
Identities = 48/189 (25%), Positives = 92/189 (48%), Gaps = 3/189 (1%)
Frame = +3
Query: 228 SAINLFYVLLVPAVILWYTYWRMSRRRLYELAEKLNGPKGLPLIGNALEFVGGSAEIFSN 407
+++ + +LL+ A L+ + R+ L + ++ P L G+ EF
Sbjct: 22 TSLLILLLLLIKAAQLY-----LHRQWLLKALQQFPCPPSHWLFGHIQEFQHDQE--LQR 74
Query: 408 IIQKSLAFDNESVVKIWIGPRLLVFLYDPRDVEVILSSHVHIDKADEYRFFKPWLGNGLL 587
I ++ F + IW G ++ V LYDP ++VIL Y+F PW+G LL
Sbjct: 75 IQERVKTFPSACPYWIW-GGKVRVQLYDPDYMKVILGRS-DPKSHGSYKFLAPWIGYSLL 132
Query: 588 ISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVEKLNKEAG---TFDCHDYMSEC 758
+ GQ W HR+++ P FH ++LK ++ L + R +++K + G + ++S
Sbjct: 133 LLNGQTWFQHRRMLTPAFHYDILKPYVGLMADSVRVMLDKWEELLGQDSPLEFFQHVSLM 192
Query: 759 TVEILLETA 785
T++ ++++A
Sbjct: 193 TLDTIMKSA 201
>BC028102-1|AAH28102.1| 509|Homo sapiens cytochrome P450, family 4,
subfamily X, polypeptide 1 protein.
Length = 509
Score = 69.3 bits (162), Expect = 3e-11
Identities = 39/128 (30%), Positives = 67/128 (52%), Gaps = 7/128 (5%)
Frame = +3
Query: 456 WIGPRLLVF-LYDPRDVEVILSSHVHIDKADEY--RFFKPWLGNGLLISTGQKWRSHRKL 626
WIGP F +YDP + +LS D +Y +F P LG GL G KW HR+L
Sbjct: 83 WIGPFQAFFCIYDPDYAKTLLS---RTDPKSQYLQKFSPPLLGKGLAALDGPKWFQHRRL 139
Query: 627 IAPTFHLNVLKSFIDLFNANSRAVVEKLNKEAGTFD----CHDYMSECTVEILLETAMGV 794
+ P FH N+LK++I++ + + +++K K T D +++++ +++I+++ A
Sbjct: 140 LTPGFHFNILKAYIEVMAHSVKMMLDKWEKICSTQDTSVEVYEHINSMSLDIIMKCAFSK 199
Query: 795 SKTTQDQS 818
Q S
Sbjct: 200 ETNCQTNS 207
>AY358537-1|AAQ88901.1| 509|Homo sapiens EFSW1929 protein.
Length = 509
Score = 69.3 bits (162), Expect = 3e-11
Identities = 39/128 (30%), Positives = 67/128 (52%), Gaps = 7/128 (5%)
Frame = +3
Query: 456 WIGPRLLVF-LYDPRDVEVILSSHVHIDKADEY--RFFKPWLGNGLLISTGQKWRSHRKL 626
WIGP F +YDP + +LS D +Y +F P LG GL G KW HR+L
Sbjct: 83 WIGPFQAFFCIYDPDYAKTLLS---RTDPKSQYLQKFSPPLLGKGLAALDGPKWFQHRRL 139
Query: 627 IAPTFHLNVLKSFIDLFNANSRAVVEKLNKEAGTFD----CHDYMSECTVEILLETAMGV 794
+ P FH N+LK++I++ + + +++K K T D +++++ +++I+++ A
Sbjct: 140 LTPGFHFNILKAYIEVMAHSVKMMLDKWEKICSTQDTSVEVYEHINSMSLDIIMKCAFSK 199
Query: 795 SKTTQDQS 818
Q S
Sbjct: 200 ETNCQTNS 207
>AY280371-1|AAQ21367.1| 519|Homo sapiens cytochrome P450 4A22K
protein.
Length = 519
Score = 69.3 bits (162), Expect = 3e-11
Identities = 48/189 (25%), Positives = 92/189 (48%), Gaps = 3/189 (1%)
Frame = +3
Query: 228 SAINLFYVLLVPAVILWYTYWRMSRRRLYELAEKLNGPKGLPLIGNALEFVGGSAEIFSN 407
+++ + +LL+ A L+ + R+ L + ++ P L G+ EF
Sbjct: 22 TSLLILLLLLIKAAQLY-----LHRQWLLKALQQFPCPPSHWLFGHIQEFQHDQE--LQR 74
Query: 408 IIQKSLAFDNESVVKIWIGPRLLVFLYDPRDVEVILSSHVHIDKADEYRFFKPWLGNGLL 587
I ++ F + IW G ++ V LYDP ++VIL Y+F PW+G LL
Sbjct: 75 IQERVKTFPSACPYWIW-GGKVRVQLYDPDYMKVILGRS-DPKSHGSYKFLAPWIGYSLL 132
Query: 588 ISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVEKLNKEAG---TFDCHDYMSEC 758
+ GQ W HR+++ P FH ++LK ++ L + R +++K + G + ++S
Sbjct: 133 LLNGQTWFQHRRMLTPAFHYDILKPYVGLMADSVRVMLDKWEELLGQDSPLEFFQHVSLM 192
Query: 759 TVEILLETA 785
T++ ++++A
Sbjct: 193 TLDTIMKSA 201
>AM040940-1|CAJ13826.1| 509|Homo sapiens cytochrome P450 protein.
Length = 509
Score = 69.3 bits (162), Expect = 3e-11
Identities = 39/128 (30%), Positives = 67/128 (52%), Gaps = 7/128 (5%)
Frame = +3
Query: 456 WIGPRLLVF-LYDPRDVEVILSSHVHIDKADEY--RFFKPWLGNGLLISTGQKWRSHRKL 626
WIGP F +YDP + +LS D +Y +F P LG GL G KW HR+L
Sbjct: 83 WIGPFQAFFCIYDPDYAKTLLS---RTDPKSQYLQKFSPPLLGKGLAALDGPKWFQHRRL 139
Query: 627 IAPTFHLNVLKSFIDLFNANSRAVVEKLNKEAGTFD----CHDYMSECTVEILLETAMGV 794
+ P FH N+LK++I++ + + +++K K T D +++++ +++I+++ A
Sbjct: 140 LTPGFHFNILKAYIEVMAHSVKMMLDKWEKICSTQDTSVEVYEHINSMSLDIIMKCAFSK 199
Query: 795 SKTTQDQS 818
Q S
Sbjct: 200 ETNCQTNS 207
>AL450996-1|CAH71035.1| 509|Homo sapiens cytochrome P450, family 4,
subfamily X, polypeptide 1 protein.
Length = 509
Score = 69.3 bits (162), Expect = 3e-11
Identities = 39/128 (30%), Positives = 67/128 (52%), Gaps = 7/128 (5%)
Frame = +3
Query: 456 WIGPRLLVF-LYDPRDVEVILSSHVHIDKADEY--RFFKPWLGNGLLISTGQKWRSHRKL 626
WIGP F +YDP + +LS D +Y +F P LG GL G KW HR+L
Sbjct: 83 WIGPFQAFFCIYDPDYAKTLLS---RTDPKSQYLQKFSPPLLGKGLAALDGPKWFQHRRL 139
Query: 627 IAPTFHLNVLKSFIDLFNANSRAVVEKLNKEAGTFD----CHDYMSECTVEILLETAMGV 794
+ P FH N+LK++I++ + + +++K K T D +++++ +++I+++ A
Sbjct: 140 LTPGFHFNILKAYIEVMAHSVKMMLDKWEKICSTQDTSVEVYEHINSMSLDIIMKCAFSK 199
Query: 795 SKTTQDQS 818
Q S
Sbjct: 200 ETNCQTNS 207
>AK098065-1|BAC05226.1| 509|Homo sapiens protein ( Homo sapiens
cDNA FLJ40746 fis, clone TRACH2000359, weakly similar to
CYTOCHROME P450 4A4 (EC 1.14.14.1). ).
Length = 509
Score = 69.3 bits (162), Expect = 3e-11
Identities = 39/128 (30%), Positives = 67/128 (52%), Gaps = 7/128 (5%)
Frame = +3
Query: 456 WIGPRLLVF-LYDPRDVEVILSSHVHIDKADEY--RFFKPWLGNGLLISTGQKWRSHRKL 626
WIGP F +YDP + +LS D +Y +F P LG GL G KW HR+L
Sbjct: 83 WIGPFQAFFCIYDPDYAKTLLS---RTDPKSQYLQKFSPPLLGKGLAALDGPKWFQHRRL 139
Query: 627 IAPTFHLNVLKSFIDLFNANSRAVVEKLNKEAGTFD----CHDYMSECTVEILLETAMGV 794
+ P FH N+LK++I++ + + +++K K T D +++++ +++I+++ A
Sbjct: 140 LTPGFHFNILKAYIEVMAHSVKMMLDKWEKICSTQDTSVEVYEHINSMSLDIIMKCAFSK 199
Query: 795 SKTTQDQS 818
Q S
Sbjct: 200 ETNCQTNS 207
>AK091806-1|BAC03751.1| 444|Homo sapiens protein ( Homo sapiens
cDNA FLJ34487 fis, clone HLUNG2004273, weakly similar to
CYTOCHROME P450 4A4 (EC 1.14.14.1). ).
Length = 444
Score = 69.3 bits (162), Expect = 3e-11
Identities = 39/128 (30%), Positives = 67/128 (52%), Gaps = 7/128 (5%)
Frame = +3
Query: 456 WIGPRLLVF-LYDPRDVEVILSSHVHIDKADEY--RFFKPWLGNGLLISTGQKWRSHRKL 626
WIGP F +YDP + +LS D +Y +F P LG GL G KW HR+L
Sbjct: 18 WIGPFQAFFCIYDPDYAKTLLS---RTDPKSQYLQKFSPPLLGKGLAALDGPKWFQHRRL 74
Query: 627 IAPTFHLNVLKSFIDLFNANSRAVVEKLNKEAGTFD----CHDYMSECTVEILLETAMGV 794
+ P FH N+LK++I++ + + +++K K T D +++++ +++I+++ A
Sbjct: 75 LTPGFHFNILKAYIEVMAHSVKMMLDKWEKICSTQDTSVEVYEHINSMSLDIIMKCAFSK 134
Query: 795 SKTTQDQS 818
Q S
Sbjct: 135 ETNCQTNS 142
>AK131355-1|BAD18508.1| 508|Homo sapiens protein ( Homo sapiens
cDNA FLJ16384 fis, clone TLIVE2007607, weakly similar
to CYTOCHROME P450 4A4 (EC 1.14.14.1). ).
Length = 508
Score = 68.9 bits (161), Expect = 4e-11
Identities = 39/128 (30%), Positives = 67/128 (52%), Gaps = 7/128 (5%)
Frame = +3
Query: 456 WIGPRLLVF-LYDPRDVEVILSSHVHIDKADEY--RFFKPWLGNGLLISTGQKWRSHRKL 626
WIGP F +YDP + +LS D +Y +F P LG GL G KW HR+L
Sbjct: 82 WIGPFQAFFCIYDPDYAKTLLS---RTDPKSQYLQKFSPPLLGKGLAALDGPKWFQHRRL 138
Query: 627 IAPTFHLNVLKSFIDLFNANSRAVVEKLNKEAGTFD----CHDYMSECTVEILLETAMGV 794
+ P FH N+LK++I++ + + +++K K T D +++++ +++I+++ A
Sbjct: 139 LTPGFHFNILKAYIEVMAHSVKMMLDKWEKICSTQDTSVEVYEHINSMSLDIVMKCAFSK 198
Query: 795 SKTTQDQS 818
Q S
Sbjct: 199 ETNCQTNS 206
>AF208532-1|AAF76722.1| 519|Homo sapiens fatty acid
omega-hydroxylase CYP4A11 protein.
Length = 519
Score = 66.9 bits (156), Expect = 2e-10
Identities = 49/189 (25%), Positives = 92/189 (48%), Gaps = 3/189 (1%)
Frame = +3
Query: 228 SAINLFYVLLVPAVILWYTYWRMSRRRLYELAEKLNGPKGLPLIGNALEFVGGSAEIFSN 407
+++ + +LL+ A L+ + R+ L + ++ P L G+ EF
Sbjct: 22 TSLLILLLLLIKAAQLY-----LHRQWLLKALQQFPCPPSHWLFGHIQEFQHDQE--LQR 74
Query: 408 IIQKSLAFDNESVVKIWIGPRLLVFLYDPRDVEVILSSHVHIDKADEYRFFKPWLGNGLL 587
I ++ F + IW G ++ V LYDP ++VIL YRF P +G GLL
Sbjct: 75 IQERVKTFPSACPYWIW-GGKVRVQLYDPDYMKVILGRS-DPKSHGSYRFLAPRIGYGLL 132
Query: 588 ISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVEKLNKEAG---TFDCHDYMSEC 758
+ GQ W HR+++ P FH ++LK ++ L + R +++K + G + ++S
Sbjct: 133 LLNGQTWFQHRRMLTPAFHNDILKPYVGLMADSVRVMLDKWEELLGQDSPLEVFQHVSLM 192
Query: 759 TVEILLETA 785
T++ ++++A
Sbjct: 193 TLDTIMKSA 201
>BC142690-1|AAI42691.1| 357|Homo sapiens CYP4A22 protein protein.
Length = 357
Score = 66.5 bits (155), Expect = 2e-10
Identities = 48/189 (25%), Positives = 92/189 (48%), Gaps = 3/189 (1%)
Frame = +3
Query: 228 SAINLFYVLLVPAVILWYTYWRMSRRRLYELAEKLNGPKGLPLIGNALEFVGGSAEIFSN 407
+++ + +LL+ A L+ + R+ L + ++ P L G+ EF
Sbjct: 22 TSLLILLLLLIKAAQLY-----LHRQWLLKALQQFPCPPSHWLFGHIQEFQHDQE--LQR 74
Query: 408 IIQKSLAFDNESVVKIWIGPRLLVFLYDPRDVEVILSSHVHIDKADEYRFFKPWLGNGLL 587
I ++ F + IW G ++ V LYDP ++VIL Y+F P +G GLL
Sbjct: 75 IQERVKTFPSACPYWIW-GGKVRVQLYDPDYMKVILGRS-DPKSHGSYKFLAPRIGYGLL 132
Query: 588 ISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVEKLNKEAG---TFDCHDYMSEC 758
+ GQ W HR+++ P FH ++LK ++ L + R +++K + G + ++S
Sbjct: 133 LLNGQTWFQHRRMLTPAFHYDILKPYVGLMADSVRVMLDKWEELLGQDSPLEVFQHVSLM 192
Query: 759 TVEILLETA 785
T++ ++++A
Sbjct: 193 TLDTIMKSA 201
>AY696295-1|AAU10524.1| 292|Homo sapiens cytochrome P450 protein.
Length = 292
Score = 66.5 bits (155), Expect = 2e-10
Identities = 40/158 (25%), Positives = 79/158 (50%), Gaps = 2/158 (1%)
Frame = +3
Query: 240 LFYVLLVPAVILWYTYWRMSRRRLYELAEKL-NGPKGLPLIGNALEFVGGSAEIFSNIIQ 416
L +LL +++L+ RRR A L P G+ + E++ +++
Sbjct: 15 LLLILLCMSLLLFQVIRLYQRRRWTIRAMHLFPAPPAHWFYGHKESYPVKEFEVYPELME 74
Query: 417 KSLAFDNESVVKIWIGPRLLVF-LYDPRDVEVILSSHVHIDKADEYRFFKPWLGNGLLIS 593
K V +W+GP + F ++DP V+++L + A ++ + W+G GL+
Sbjct: 75 KY-----PCAVPLWVGPFTMFFNIHDPDYVKILLKRQ-NPKSAVSHKILESWVGRGLVTL 128
Query: 594 TGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVEK 707
G KW+ HR+++ P F++++LK FI + + + R ++ K
Sbjct: 129 DGSKWKKHRQIVKPGFNISILKIFITMMSKSVRMMLNK 166
>AL135960-11|CAI19738.1| 455|Homo sapiens cytochrome P450, family
4, subfamily A, polypeptide 22 protein.
Length = 455
Score = 65.7 bits (153), Expect = 4e-10
Identities = 48/189 (25%), Positives = 92/189 (48%), Gaps = 3/189 (1%)
Frame = +3
Query: 228 SAINLFYVLLVPAVILWYTYWRMSRRRLYELAEKLNGPKGLPLIGNALEFVGGSAEIFSN 407
+++ + +LL+ A L+ + R+ L + ++ P L G+ EF
Sbjct: 22 TSLLILLLLLIKAAQLY-----LHRQWLLKALQQFPCPPSHWLFGHIQEFQHDQE--LQR 74
Query: 408 IIQKSLAFDNESVVKIWIGPRLLVFLYDPRDVEVILSSHVHIDKADEYRFFKPWLGNGLL 587
I ++ F + IW G ++ V LYDP ++VIL Y+F P +G GLL
Sbjct: 75 IQERVKTFPSACPYWIW-GGKVRVQLYDPDYMKVILGRS-DPKSHGSYKFLAPRIGYGLL 132
Query: 588 ISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVEKLNKEAG---TFDCHDYMSEC 758
+ GQ W HR+++ P FH ++LK ++ L + R +++K + G + ++S
Sbjct: 133 LLNGQTWFQHRRMLTPAFHNDILKPYVGLMADSVRVMLDKWEELLGQDSPLEVFQHVSLM 192
Query: 759 TVEILLETA 785
T++ ++++A
Sbjct: 193 TLDTIMKSA 201
>AL135960-10|CAI19736.1| 421|Homo sapiens cytochrome P450, family
4, subfamily A, polypeptide 22 protein.
Length = 421
Score = 65.7 bits (153), Expect = 4e-10
Identities = 48/189 (25%), Positives = 92/189 (48%), Gaps = 3/189 (1%)
Frame = +3
Query: 228 SAINLFYVLLVPAVILWYTYWRMSRRRLYELAEKLNGPKGLPLIGNALEFVGGSAEIFSN 407
+++ + +LL+ A L+ + R+ L + ++ P L G+ EF
Sbjct: 22 TSLLILLLLLIKAAQLY-----LHRQWLLKALQQFPCPPSHWLFGHIQEFQHDQE--LQR 74
Query: 408 IIQKSLAFDNESVVKIWIGPRLLVFLYDPRDVEVILSSHVHIDKADEYRFFKPWLGNGLL 587
I ++ F + IW G ++ V LYDP ++VIL Y+F P +G GLL
Sbjct: 75 IQERVKTFPSACPYWIW-GGKVRVQLYDPDYMKVILGRS-DPKSHGSYKFLAPRIGYGLL 132
Query: 588 ISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVEKLNKEAG---TFDCHDYMSEC 758
+ GQ W HR+++ P FH ++LK ++ L + R +++K + G + ++S
Sbjct: 133 LLNGQTWFQHRRMLTPAFHNDILKPYVGLMADSVRVMLDKWEELLGQDSPLEVFQHVSLM 192
Query: 759 TVEILLETA 785
T++ ++++A
Sbjct: 193 TLDTIMKSA 201
>AL135960-9|CAI19737.1| 519|Homo sapiens cytochrome P450, family 4,
subfamily A, polypeptide 22 protein.
Length = 519
Score = 65.7 bits (153), Expect = 4e-10
Identities = 48/189 (25%), Positives = 92/189 (48%), Gaps = 3/189 (1%)
Frame = +3
Query: 228 SAINLFYVLLVPAVILWYTYWRMSRRRLYELAEKLNGPKGLPLIGNALEFVGGSAEIFSN 407
+++ + +LL+ A L+ + R+ L + ++ P L G+ EF
Sbjct: 22 TSLLILLLLLIKAAQLY-----LHRQWLLKALQQFPCPPSHWLFGHIQEFQHDQE--LQR 74
Query: 408 IIQKSLAFDNESVVKIWIGPRLLVFLYDPRDVEVILSSHVHIDKADEYRFFKPWLGNGLL 587
I ++ F + IW G ++ V LYDP ++VIL Y+F P +G GLL
Sbjct: 75 IQERVKTFPSACPYWIW-GGKVRVQLYDPDYMKVILGRS-DPKSHGSYKFLAPRIGYGLL 132
Query: 588 ISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVEKLNKEAG---TFDCHDYMSEC 758
+ GQ W HR+++ P FH ++LK ++ L + R +++K + G + ++S
Sbjct: 133 LLNGQTWFQHRRMLTPAFHNDILKPYVGLMADSVRVMLDKWEELLGQDSPLEVFQHVSLM 192
Query: 759 TVEILLETA 785
T++ ++++A
Sbjct: 193 TLDTIMKSA 201
>AK097373-1|BAC05026.1| 340|Homo sapiens protein ( Homo sapiens
cDNA FLJ40054 fis, clone TBAES2000315, weakly similar to
CYTOCHROME P450 4A1 (EC 1.14.15.3). ).
Length = 340
Score = 65.7 bits (153), Expect = 4e-10
Identities = 39/159 (24%), Positives = 80/159 (50%), Gaps = 3/159 (1%)
Frame = +3
Query: 240 LFYVLLVPAVILWYTYWRMSRRRLYELAEK--LNGPKGLPLIGNALEFVGGSAEIFSNII 413
L +LL +++L+ R+ RRR + + P G+ + E++ ++
Sbjct: 15 LLLILLCMSLLLFQVI-RLYRRRRWTIRAMHLFPAPPAHWFYGHKESYPVKEFEVYPELM 73
Query: 414 QKSLAFDNESVVKIWIGPRLLVF-LYDPRDVEVILSSHVHIDKADEYRFFKPWLGNGLLI 590
+K V +W+GP + F ++DP V+++L A ++ + W+G GL+
Sbjct: 74 EKY-----PCAVPLWVGPFTMFFNIHDPDYVKILLKRQ-DPKSAVSHKILESWVGRGLVT 127
Query: 591 STGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVEK 707
G KW+ HR+++ P F++++LK FI + + + R ++ K
Sbjct: 128 LDGSKWKKHRQIVKPGFNISILKIFITMMSKSVRMMLNK 166
>AY358631-1|AAQ88994.1| 505|Homo sapiens EPSW3060 protein.
Length = 505
Score = 63.7 bits (148), Expect = 2e-09
Identities = 28/88 (31%), Positives = 51/88 (57%), Gaps = 1/88 (1%)
Frame = +3
Query: 447 VKIWIGPRLLVF-LYDPRDVEVILSSHVHIDKADEYRFFKPWLGNGLLISTGQKWRSHRK 623
V +W+GP + F ++DP D IL A ++ + W+G GL+ G KW+ HR+
Sbjct: 80 VPLWVGPFTMFFSVHDP-DYAKILLKRQDPKSAVSHKILESWVGRGLVTLDGSKWKKHRQ 138
Query: 624 LIAPTFHLNVLKSFIDLFNANSRAVVEK 707
++ P F++++LK FI + + + R ++ K
Sbjct: 139 IVKPGFNISILKIFITMMSESVRMMLNK 166
>AY262056-1|AAO89257.1| 505|Homo sapiens cytochrome P450 protein.
Length = 505
Score = 63.7 bits (148), Expect = 2e-09
Identities = 28/88 (31%), Positives = 51/88 (57%), Gaps = 1/88 (1%)
Frame = +3
Query: 447 VKIWIGPRLLVF-LYDPRDVEVILSSHVHIDKADEYRFFKPWLGNGLLISTGQKWRSHRK 623
V +W+GP + F ++DP D IL A ++ + W+G GL+ G KW+ HR+
Sbjct: 80 VPLWVGPFTMFFSVHDP-DYAKILLKRQDPKSAVSHKILESWVGRGLVTLDGSKWKKHRQ 138
Query: 624 LIAPTFHLNVLKSFIDLFNANSRAVVEK 707
++ P F++++LK FI + + + R ++ K
Sbjct: 139 IVKPGFNISILKIFITMMSESVRMMLNK 166
>AL450996-2|CAH71036.1| 505|Homo sapiens cytochrome P450, family 4,
subfamily Z, polypeptide 1 protein.
Length = 505
Score = 63.7 bits (148), Expect = 2e-09
Identities = 28/88 (31%), Positives = 51/88 (57%), Gaps = 1/88 (1%)
Frame = +3
Query: 447 VKIWIGPRLLVF-LYDPRDVEVILSSHVHIDKADEYRFFKPWLGNGLLISTGQKWRSHRK 623
V +W+GP + F ++DP D IL A ++ + W+G GL+ G KW+ HR+
Sbjct: 80 VPLWVGPFTMFFSVHDP-DYAKILLKRQDPKSAVSHKILESWVGRGLVTLDGSKWKKHRQ 138
Query: 624 LIAPTFHLNVLKSFIDLFNANSRAVVEK 707
++ P F++++LK FI + + + R ++ K
Sbjct: 139 IVKPGFNISILKIFITMMSESVRMMLNK 166
>AL135960-6|CAI19734.1| 505|Homo sapiens cytochrome P450, family 4,
subfamily Z, polypeptide 1 protein.
Length = 505
Score = 63.7 bits (148), Expect = 2e-09
Identities = 28/88 (31%), Positives = 51/88 (57%), Gaps = 1/88 (1%)
Frame = +3
Query: 447 VKIWIGPRLLVF-LYDPRDVEVILSSHVHIDKADEYRFFKPWLGNGLLISTGQKWRSHRK 623
V +W+GP + F ++DP D IL A ++ + W+G GL+ G KW+ HR+
Sbjct: 80 VPLWVGPFTMFFSVHDP-DYAKILLKRQDPKSAVSHKILESWVGRGLVTLDGSKWKKHRQ 138
Query: 624 LIAPTFHLNVLKSFIDLFNANSRAVVEK 707
++ P F++++LK FI + + + R ++ K
Sbjct: 139 IVKPGFNISILKIFITMMSESVRMMLNK 166
>AY151049-1|AAN72312.1| 497|Homo sapiens pulmonary cytochrome P450
4B1 variant protein.
Length = 497
Score = 54.4 bits (125), Expect = 1e-06
Identities = 26/80 (32%), Positives = 43/80 (53%), Gaps = 3/80 (3%)
Frame = +3
Query: 573 GNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVEKLN---KEAGTFDCHD 743
G GLL+ G KW HRKL+ P FH +VLK ++ +F ++R +++K +E +FD
Sbjct: 108 GRGLLVLEGPKWLQHRKLLTPGFHYDVLKPYVAVFTESTRIMLDKWEEKAREGKSFDIFC 167
Query: 744 YMSECTVEILLETAMGVSKT 803
+ + L++ G T
Sbjct: 168 DVGHMALNTLMKCTFGRGDT 187
>AL593856-5|CAI16983.1| 497|Homo sapiens cytochrome P450, family 4,
subfamily B, polypeptide 1 protein.
Length = 497
Score = 54.4 bits (125), Expect = 1e-06
Identities = 26/80 (32%), Positives = 43/80 (53%), Gaps = 3/80 (3%)
Frame = +3
Query: 573 GNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVEKLN---KEAGTFDCHD 743
G GLL+ G KW HRKL+ P FH +VLK ++ +F ++R +++K +E +FD
Sbjct: 108 GRGLLVLEGPKWLQHRKLLTPGFHYDVLKPYVAVFTESTRIMLDKWEEKAREGKSFDIFC 167
Query: 744 YMSECTVEILLETAMGVSKT 803
+ + L++ G T
Sbjct: 168 DVGHMALNTLMKCTFGRGDT 187
>AL356793-2|CAI22558.1| 497|Homo sapiens cytochrome P450, family 4,
subfamily B, polypeptide 1 protein.
Length = 497
Score = 54.4 bits (125), Expect = 1e-06
Identities = 26/80 (32%), Positives = 43/80 (53%), Gaps = 3/80 (3%)
Frame = +3
Query: 573 GNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVEKLN---KEAGTFDCHD 743
G GLL+ G KW HRKL+ P FH +VLK ++ +F ++R +++K +E +FD
Sbjct: 108 GRGLLVLEGPKWLQHRKLLTPGFHYDVLKPYVAVFTESTRIMLDKWEEKAREGKSFDIFC 167
Query: 744 YMSECTVEILLETAMGVSKT 803
+ + L++ G T
Sbjct: 168 DVGHMALNTLMKCTFGRGDT 187
>J04449-1|AAA35747.1| 502|Homo sapiens cytochrome P450 nifedipine
oxidase protein.
Length = 502
Score = 48.8 bits (111), Expect = 5e-05
Identities = 43/189 (22%), Positives = 84/189 (44%), Gaps = 5/189 (2%)
Frame = +3
Query: 246 YVLLVPAVILWYTYWRMSRRRLYELAEKLNGPKGLPLIGNALEFVGGSAEIFSNIIQKSL 425
++LL +++L Y Y S +L + GP LP +GN L + G +F K
Sbjct: 12 WLLLAVSLVLLYLYGTHSHGLFKKLG--IPGPTPLPFLGNILSYHKGFC-MFDMECHKKY 68
Query: 426 AFDNESVVKIWIGPRLLVFLYDPRDVEVILSSHVHIDKADEYRFFKP--WLGNGLLISTG 599
V + G + ++ + DP ++ +L + + R F P ++ + + I+
Sbjct: 69 G----KVCGFYDGQQPVLAITDPDMIKTVLVKECYSVFTNR-RPFGPVGFMKSAISIAED 123
Query: 600 QKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVEKLNKEAGT---FDCHDYMSECTVEI 770
++W+ R L++PTF LK + + +V L +EA T D ++++
Sbjct: 124 EEWKRLRSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDV 183
Query: 771 LLETAMGVS 797
+ T+ GV+
Sbjct: 184 ITSTSFGVN 192
>D00408-1|BAA00310.1| 503|Homo sapiens cytochrome P-450 HFLa
protein.
Length = 503
Score = 48.8 bits (111), Expect = 5e-05
Identities = 45/189 (23%), Positives = 83/189 (43%), Gaps = 5/189 (2%)
Frame = +3
Query: 246 YVLLVPAVILWYTYWRMSRRRLYELAEKLNGPKGLPLIGNALEFVGGSAEIFSNIIQKSL 425
++LL ++IL Y Y + +L + GP LP +GNAL F G +K
Sbjct: 12 WLLLAVSLILLYLYGTRTHGLFKKLG--IPGPTPLPFLGNALSFRKGYWTFDMECYKKY- 68
Query: 426 AFDNESVVKIWIGPRLLVFLYDPRDVEVILSSHVHIDKADEYRFFKP--WLGNGLLISTG 599
V I+ + ++ + DP ++ +L + + R F P ++ N + I+
Sbjct: 69 ----RKVWGIYDCQQPMLAITDPDMIKTVLVKECYSVFTNR-RPFGPVGFMKNAISIAED 123
Query: 600 QKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVEKLNKEAGT---FDCHDYMSECTVEI 770
++W+ R L++PTF LK + + +V L +EA T ++++
Sbjct: 124 EEWKRIRSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKHVFGAYSMDV 183
Query: 771 LLETAMGVS 797
+ T+ GVS
Sbjct: 184 ITSTSFGVS 192
>BC067436-1|AAH67436.1| 503|Homo sapiens cytochrome P450, family 3,
subfamily A, polypeptide 7 protein.
Length = 503
Score = 48.8 bits (111), Expect = 5e-05
Identities = 45/189 (23%), Positives = 83/189 (43%), Gaps = 5/189 (2%)
Frame = +3
Query: 246 YVLLVPAVILWYTYWRMSRRRLYELAEKLNGPKGLPLIGNALEFVGGSAEIFSNIIQKSL 425
++LL ++IL Y Y + +L + GP LP +GNAL F G +K
Sbjct: 12 WLLLAVSLILLYLYGTRTHGLFKKLG--IPGPTPLPFLGNALSFRKGYWTFDMECYKKY- 68
Query: 426 AFDNESVVKIWIGPRLLVFLYDPRDVEVILSSHVHIDKADEYRFFKP--WLGNGLLISTG 599
V I+ + ++ + DP ++ +L + + R F P ++ N + I+
Sbjct: 69 ----RKVWGIYDCQQPMLAITDPDMIKTVLVKECYSVFTNR-RPFGPVGFMKNAISIAED 123
Query: 600 QKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVEKLNKEAGT---FDCHDYMSECTVEI 770
++W+ R L++PTF LK + + +V L +EA T ++++
Sbjct: 124 EEWKRIRSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKHVFGAYSMDV 183
Query: 771 LLETAMGVS 797
+ T+ GVS
Sbjct: 184 ITSTSFGVS 192
>AF315325-1|AAG48618.1| 535|Homo sapiens cytochrome P450 variant
3A7 protein.
Length = 535
Score = 48.8 bits (111), Expect = 5e-05
Identities = 45/189 (23%), Positives = 83/189 (43%), Gaps = 5/189 (2%)
Frame = +3
Query: 246 YVLLVPAVILWYTYWRMSRRRLYELAEKLNGPKGLPLIGNALEFVGGSAEIFSNIIQKSL 425
++LL ++IL Y Y + +L + GP LP +GNAL F G +K
Sbjct: 12 WLLLAVSLILLYLYGTRTHGLFKKLG--IPGPTPLPFLGNALSFRKGYWTFDMECYKKY- 68
Query: 426 AFDNESVVKIWIGPRLLVFLYDPRDVEVILSSHVHIDKADEYRFFKP--WLGNGLLISTG 599
V I+ + ++ + DP ++ +L + + R F P ++ N + I+
Sbjct: 69 ----RKVWGIYDCQQPMLAITDPDMIKTVLVKECYSVFTNR-RPFGPVGFMKNAISIAED 123
Query: 600 QKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVEKLNKEAGT---FDCHDYMSECTVEI 770
++W+ R L++PTF LK + + +V L +EA T ++++
Sbjct: 124 EEWKRIRSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKHVFGAYSMDV 183
Query: 771 LLETAMGVS 797
+ T+ GVS
Sbjct: 184 ITSTSFGVS 192
>AF280107-3|AAG32289.1| 503|Homo sapiens cytochrome P450
polypeptide 7 protein.
Length = 503
Score = 48.8 bits (111), Expect = 5e-05
Identities = 45/189 (23%), Positives = 83/189 (43%), Gaps = 5/189 (2%)
Frame = +3
Query: 246 YVLLVPAVILWYTYWRMSRRRLYELAEKLNGPKGLPLIGNALEFVGGSAEIFSNIIQKSL 425
++LL ++IL Y Y + +L + GP LP +GNAL F G +K
Sbjct: 12 WLLLAVSLILLYLYGTRTHGLFKKLG--IPGPTPLPFLGNALSFRKGYWTFDMECYKKY- 68
Query: 426 AFDNESVVKIWIGPRLLVFLYDPRDVEVILSSHVHIDKADEYRFFKP--WLGNGLLISTG 599
V I+ + ++ + DP ++ +L + + R F P ++ N + I+
Sbjct: 69 ----RKVWGIYDCQQPMLAITDPDMIKTVLVKECYSVFTNR-RPFGPVGFMKNAISIAED 123
Query: 600 QKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVEKLNKEAGT---FDCHDYMSECTVEI 770
++W+ R L++PTF LK + + +V L +EA T ++++
Sbjct: 124 EEWKRIRSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKHVFGAYSMDV 183
Query: 771 LLETAMGVS 797
+ T+ GVS
Sbjct: 184 ITSTSFGVS 192
>AJ563375-1|CAD91343.1| 503|Homo sapiens cytochrome P450 protein.
Length = 503
Score = 48.4 bits (110), Expect = 6e-05
Identities = 43/189 (22%), Positives = 84/189 (44%), Gaps = 5/189 (2%)
Frame = +3
Query: 246 YVLLVPAVILWYTYWRMSRRRLYELAEKLNGPKGLPLIGNALEFVGGSAEIFSNIIQKSL 425
+VL+ +++L Y Y S +L + GP LP +GN L + G +F K
Sbjct: 12 WVLVATSLVLLYIYGTHSHGLFKKLG--IPGPTPLPFLGNILSYHKGFC-MFDMECHKKY 68
Query: 426 AFDNESVVKIWIGPRLLVFLYDPRDVEVILSSHVHIDKADEYRFFKP--WLGNGLLISTG 599
V + G + ++ + DP ++ +L + + R F P ++ + + I+
Sbjct: 69 G----KVWGFYDGQQPVLAITDPDMIKTVLVKECYSVFTNR-RPFGPVGFMKSAISIAED 123
Query: 600 QKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVEKLNKEAGT---FDCHDYMSECTVEI 770
++W+ R L++PTF LK + + +V L +EA T D ++++
Sbjct: 124 EEWKRLRSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDV 183
Query: 771 LLETAMGVS 797
+ T+ GV+
Sbjct: 184 ITSTSFGVN 192
>X12387-1|CAA30944.1| 503|Homo sapiens protein ( Human mRNA for
cytochrome P-450 (cyp3 locus). ).
Length = 503
Score = 48.0 bits (109), Expect = 9e-05
Identities = 43/189 (22%), Positives = 84/189 (44%), Gaps = 5/189 (2%)
Frame = +3
Query: 246 YVLLVPAVILWYTYWRMSRRRLYELAEKLNGPKGLPLIGNALEFVGGSAEIFSNIIQKSL 425
++LL +++L Y Y S +L + GP LP +GN L + G +F K
Sbjct: 12 WLLLAVSLVLLYLYGTHSHGLFKKLG--IPGPTPLPFLGNILSYHKGFC-MFDMECHKKY 68
Query: 426 AFDNESVVKIWIGPRLLVFLYDPRDVEVILSSHVHIDKADEYRFFKP--WLGNGLLISTG 599
V + G + ++ + DP ++ +L + + R F P ++ + + I+
Sbjct: 69 G----KVWGFYDGQQPVLAITDPDMIKTVLVKECYSVFTNR-RPFGPVGFMKSAISIAED 123
Query: 600 QKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVEKLNKEAGT---FDCHDYMSECTVEI 770
++W+ R L++PTF LK + + +V L +EA T D ++++
Sbjct: 124 EEWKRLRSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDV 183
Query: 771 LLETAMGVS 797
+ T+ GV+
Sbjct: 184 ITSTSFGVN 192
>M18907-1|AAA35745.1| 503|Homo sapiens protein ( Human P450 mRNA
encoding nifedipine oxidase, complete cds. ).
Length = 503
Score = 48.0 bits (109), Expect = 9e-05
Identities = 43/189 (22%), Positives = 84/189 (44%), Gaps = 5/189 (2%)
Frame = +3
Query: 246 YVLLVPAVILWYTYWRMSRRRLYELAEKLNGPKGLPLIGNALEFVGGSAEIFSNIIQKSL 425
++LL +++L Y Y S +L + GP LP +GN L + G +F K
Sbjct: 12 WLLLAVSLVLLYLYGTHSHGLFKKLG--IPGPTPLPFLGNILSYHKGFC-MFDMECHKKY 68
Query: 426 AFDNESVVKIWIGPRLLVFLYDPRDVEVILSSHVHIDKADEYRFFKP--WLGNGLLISTG 599
V + G + ++ + DP ++ +L + + R F P ++ + + I+
Sbjct: 69 G----KVWGFYDGQQPVLAITDPDMIKTVLVKECYSVFTNR-RPFGPVGFMKSAISIAED 123
Query: 600 QKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVEKLNKEAGT---FDCHDYMSECTVEI 770
++W+ R L++PTF LK + + +V L +EA T D ++++
Sbjct: 124 EEWKRLRSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDV 183
Query: 771 LLETAMGVS 797
+ T+ GV+
Sbjct: 184 ITSTSFGVN 192
>M14096-1|AAA35744.1| 503|Homo sapiens protein ( Human cytochrome
P-450 nifedipine oxidase mRNA, complet cds. ).
Length = 503
Score = 48.0 bits (109), Expect = 9e-05
Identities = 43/189 (22%), Positives = 84/189 (44%), Gaps = 5/189 (2%)
Frame = +3
Query: 246 YVLLVPAVILWYTYWRMSRRRLYELAEKLNGPKGLPLIGNALEFVGGSAEIFSNIIQKSL 425
++LL +++L Y Y S +L + GP LP +GN L + G +F K
Sbjct: 12 WLLLAVSLVLLYLYGTHSHGLFKKLG--IPGPTPLPFLGNILSYHKGFC-MFDMECHKKY 68
Query: 426 AFDNESVVKIWIGPRLLVFLYDPRDVEVILSSHVHIDKADEYRFFKP--WLGNGLLISTG 599
V + G + ++ + DP ++ +L + + R F P ++ + + I+
Sbjct: 69 G----KVWGFYDGQQPVLAITDPDMIKTVLVKECYSVFTNR-RPFGPVGFMKSAISIAED 123
Query: 600 QKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVEKLNKEAGT---FDCHDYMSECTVEI 770
++W+ R L++PTF LK + + +V L +EA T D ++++
Sbjct: 124 EEWKRLRSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDV 183
Query: 771 LLETAMGVS 797
+ T+ GV+
Sbjct: 184 ITSTSFGVN 192
>DQ924960-1|ABI96208.1| 503|Homo sapiens cytochrome P450 family 3
subfamily A polypeptide 4 protein.
Length = 503
Score = 48.0 bits (109), Expect = 9e-05
Identities = 43/189 (22%), Positives = 84/189 (44%), Gaps = 5/189 (2%)
Frame = +3
Query: 246 YVLLVPAVILWYTYWRMSRRRLYELAEKLNGPKGLPLIGNALEFVGGSAEIFSNIIQKSL 425
++LL +++L Y Y S +L + GP LP +GN L + G +F K
Sbjct: 12 WLLLAVSLVLLYLYGTHSHGLFKKLG--IPGPTPLPFLGNILSYHKGFC-MFDMECHKKY 68
Query: 426 AFDNESVVKIWIGPRLLVFLYDPRDVEVILSSHVHIDKADEYRFFKP--WLGNGLLISTG 599
V + G + ++ + DP ++ +L + + R F P ++ + + I+
Sbjct: 69 G----KVWGFYDGQQPVLAITDPDMIKTVLVKECYSVFTNR-RPFGPVGFMKSAISIAED 123
Query: 600 QKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVEKLNKEAGT---FDCHDYMSECTVEI 770
++W+ R L++PTF LK + + +V L +EA T D ++++
Sbjct: 124 EEWKRLRSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDV 183
Query: 771 LLETAMGVS 797
+ T+ GV+
Sbjct: 184 ITSTSFGVN 192
>DQ005611-1|AAY16980.1| 503|Homo sapiens cytochrome P450, family 3,
subfamily A, polypeptide 4 protein.
Length = 503
Score = 48.0 bits (109), Expect = 9e-05
Identities = 43/189 (22%), Positives = 84/189 (44%), Gaps = 5/189 (2%)
Frame = +3
Query: 246 YVLLVPAVILWYTYWRMSRRRLYELAEKLNGPKGLPLIGNALEFVGGSAEIFSNIIQKSL 425
++LL +++L Y Y S +L + GP LP +GN L + G +F K
Sbjct: 12 WLLLAVSLVLLYLYGTHSHGLFKKLG--IPGPTPLPFLGNILSYHKGFC-MFDMECHKKY 68
Query: 426 AFDNESVVKIWIGPRLLVFLYDPRDVEVILSSHVHIDKADEYRFFKP--WLGNGLLISTG 599
V + G + ++ + DP ++ +L + + R F P ++ + + I+
Sbjct: 69 G----KVWGFYDGQQPVLAITDPDMIKTVLVKECYSVFTNR-RPFGPVGFMKSAISIAED 123
Query: 600 QKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVEKLNKEAGT---FDCHDYMSECTVEI 770
++W+ R L++PTF LK + + +V L +EA T D ++++
Sbjct: 124 EEWKRLRSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDV 183
Query: 771 LLETAMGVS 797
+ T+ GV+
Sbjct: 184 ITSTSFGVN 192
>BC101631-1|AAI01632.1| 503|Homo sapiens cytochrome P450, subfamily
IIIA, polypeptide 4 protein.
Length = 503
Score = 48.0 bits (109), Expect = 9e-05
Identities = 43/189 (22%), Positives = 84/189 (44%), Gaps = 5/189 (2%)
Frame = +3
Query: 246 YVLLVPAVILWYTYWRMSRRRLYELAEKLNGPKGLPLIGNALEFVGGSAEIFSNIIQKSL 425
++LL +++L Y Y S +L + GP LP +GN L + G +F K
Sbjct: 12 WLLLAVSLVLLYLYGTHSHGLFKKLG--IPGPTPLPFLGNILSYHKGFC-MFDMECHKKY 68
Query: 426 AFDNESVVKIWIGPRLLVFLYDPRDVEVILSSHVHIDKADEYRFFKP--WLGNGLLISTG 599
V + G + ++ + DP ++ +L + + R F P ++ + + I+
Sbjct: 69 G----KVWGFYDGQQPVLAITDPDMIKTVLVKECYSVFTNR-RPFGPVGFMKSAISIAED 123
Query: 600 QKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVEKLNKEAGT---FDCHDYMSECTVEI 770
++W+ R L++PTF LK + + +V L +EA T D ++++
Sbjct: 124 EEWKRLRSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDV 183
Query: 771 LLETAMGVS 797
+ T+ GV+
Sbjct: 184 ITSTSFGVN 192
>BC069418-1|AAH69418.1| 503|Homo sapiens cytochrome P450, family 3,
subfamily A, polypeptide 4 protein.
Length = 503
Score = 48.0 bits (109), Expect = 9e-05
Identities = 43/189 (22%), Positives = 84/189 (44%), Gaps = 5/189 (2%)
Frame = +3
Query: 246 YVLLVPAVILWYTYWRMSRRRLYELAEKLNGPKGLPLIGNALEFVGGSAEIFSNIIQKSL 425
++LL +++L Y Y S +L + GP LP +GN L + G +F K
Sbjct: 12 WLLLAVSLVLLYLYGTHSHGLFKKLG--IPGPTPLPFLGNILSYHKGFC-MFDMECHKKY 68
Query: 426 AFDNESVVKIWIGPRLLVFLYDPRDVEVILSSHVHIDKADEYRFFKP--WLGNGLLISTG 599
V + G + ++ + DP ++ +L + + R F P ++ + + I+
Sbjct: 69 G----KVWGFYDGQQPVLAITDPDMIKTVLVKECYSVFTNR-RPFGPVGFMKSAISIAED 123
Query: 600 QKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVEKLNKEAGT---FDCHDYMSECTVEI 770
++W+ R L++PTF LK + + +V L +EA T D ++++
Sbjct: 124 EEWKRLRSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDV 183
Query: 771 LLETAMGVS 797
+ T+ GV+
Sbjct: 184 ITSTSFGVN 192
>AF280107-2|AAG32290.1| 503|Homo sapiens cytochrome P450
polypeptide 4 protein.
Length = 503
Score = 48.0 bits (109), Expect = 9e-05
Identities = 43/189 (22%), Positives = 84/189 (44%), Gaps = 5/189 (2%)
Frame = +3
Query: 246 YVLLVPAVILWYTYWRMSRRRLYELAEKLNGPKGLPLIGNALEFVGGSAEIFSNIIQKSL 425
++LL +++L Y Y S +L + GP LP +GN L + G +F K
Sbjct: 12 WLLLAVSLVLLYLYGTHSHGLFKKLG--IPGPTPLPFLGNILSYHKGFC-MFDMECHKKY 68
Query: 426 AFDNESVVKIWIGPRLLVFLYDPRDVEVILSSHVHIDKADEYRFFKP--WLGNGLLISTG 599
V + G + ++ + DP ++ +L + + R F P ++ + + I+
Sbjct: 69 G----KVWGFYDGQQPVLAITDPDMIKTVLVKECYSVFTNR-RPFGPVGFMKSAISIAED 123
Query: 600 QKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVEKLNKEAGT---FDCHDYMSECTVEI 770
++W+ R L++PTF LK + + +V L +EA T D ++++
Sbjct: 124 EEWKRLRSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDV 183
Query: 771 LLETAMGVS 797
+ T+ GV+
Sbjct: 184 ITSTSFGVN 192
>AF209389-1|AAF21034.1| 503|Homo sapiens cytochrome P450 IIIA4
protein.
Length = 503
Score = 48.0 bits (109), Expect = 9e-05
Identities = 43/189 (22%), Positives = 84/189 (44%), Gaps = 5/189 (2%)
Frame = +3
Query: 246 YVLLVPAVILWYTYWRMSRRRLYELAEKLNGPKGLPLIGNALEFVGGSAEIFSNIIQKSL 425
++LL +++L Y Y S +L + GP LP +GN L + G +F K
Sbjct: 12 WLLLAVSLVLLYLYGTHSHGLFKKLG--IPGPTPLPFLGNILSYHKGFC-MFDMECHKKY 68
Query: 426 AFDNESVVKIWIGPRLLVFLYDPRDVEVILSSHVHIDKADEYRFFKP--WLGNGLLISTG 599
V + G + ++ + DP ++ +L + + R F P ++ + + I+
Sbjct: 69 G----KVWGFYDGQQPVLAITDPDMIKTVLVKECYSVFTNR-RPFGPVGFMKSAISIAED 123
Query: 600 QKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVEKLNKEAGT---FDCHDYMSECTVEI 770
++W+ R L++PTF LK + + +V L +EA T D ++++
Sbjct: 124 EEWKRLRSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDV 183
Query: 771 LLETAMGVS 797
+ T+ GV+
Sbjct: 184 ITSTSFGVN 192
>AF182273-1|AAF13598.1| 503|Homo sapiens cytochrome P450-3A4
protein.
Length = 503
Score = 47.2 bits (107), Expect = 1e-04
Identities = 43/188 (22%), Positives = 83/188 (44%), Gaps = 5/188 (2%)
Frame = +3
Query: 249 VLLVPAVILWYTYWRMSRRRLYELAEKLNGPKGLPLIGNALEFVGGSAEIFSNIIQKSLA 428
+LL +++L Y Y S +L + GP LP +GN L + G +F K
Sbjct: 13 LLLAVSLVLLYLYGTHSHGLFKKLG--IPGPTPLPFLGNILSYHKGFC-MFDMECHKKYG 69
Query: 429 FDNESVVKIWIGPRLLVFLYDPRDVEVILSSHVHIDKADEYRFFKP--WLGNGLLISTGQ 602
V + G + ++ + DP ++ +L + + R F P ++ + + I+ +
Sbjct: 70 ----KVWGFYDGQQPVLAITDPDMIKTVLVKECYSVFTNR-RPFGPVGFMKSAISIAEDE 124
Query: 603 KWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVEKLNKEAGT---FDCHDYMSECTVEIL 773
+W+ R L++PTF LK + + +V L +EA T D +++++
Sbjct: 125 EWKRLRSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDVI 184
Query: 774 LETAMGVS 797
T+ GV+
Sbjct: 185 TSTSFGVN 192
>M13785-1|AAA35742.1| 504|Homo sapiens protein ( Human liver
glucocorticoid-inducible cytochrome P-450 (HLp) mRNA,
complete cds. ).
Length = 504
Score = 43.6 bits (98), Expect = 0.002
Identities = 39/188 (20%), Positives = 82/188 (43%), Gaps = 4/188 (2%)
Frame = +3
Query: 246 YVLLVPAVILWYTYWRMSRRRLYELAEKLNGPKGLPLIGNALEFVGGSAEIFSNIIQKSL 425
++LL +++L Y Y S +L + GP LP +GN L + G +F K
Sbjct: 12 WLLLAVSLVLLYLYGTHSHGLFKKLG--IPGPTPLPFLGNILSYHKGFC-MFDMECHKKY 68
Query: 426 AFDNESVVKIWIGPRLLVFLYDPRDVEVILSSHVHIDKADEYRFFKP-WLGNGLLISTGQ 602
V + G + ++ + DP ++++L + + F ++ + + I+ +
Sbjct: 69 G----KVWGFYDGQQPVLAITDPDMIKLVLVKECYSVFTNREPFGPVGFMKSAISIAEDE 124
Query: 603 KWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVEKLNKEAGT---FDCHDYMSECTVEIL 773
+W+ R L++PTF LK + + +V L +E T D +++++
Sbjct: 125 EWKRLRSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLRRERETGKPVTLKDVFGAYSMDVI 184
Query: 774 LETAMGVS 797
++ GV+
Sbjct: 185 TSSSFGVN 192
>D00003-1|BAA00001.1| 504|Homo sapiens cytochrome P-450 protein.
Length = 504
Score = 43.6 bits (98), Expect = 0.002
Identities = 39/188 (20%), Positives = 82/188 (43%), Gaps = 4/188 (2%)
Frame = +3
Query: 246 YVLLVPAVILWYTYWRMSRRRLYELAEKLNGPKGLPLIGNALEFVGGSAEIFSNIIQKSL 425
++LL +++L Y Y S +L + GP LP +GN L + G +F K
Sbjct: 12 WLLLAVSLVLLYLYGTHSHGLFKKLG--IPGPTPLPFLGNILSYHKGFC-MFDMECHKKY 68
Query: 426 AFDNESVVKIWIGPRLLVFLYDPRDVEVILSSHVHIDKADEYRFFKP-WLGNGLLISTGQ 602
V + G + ++ + DP ++++L + + F ++ + + I+ +
Sbjct: 69 G----KVWGFYDGQQPVLAITDPDMIKLVLVKECYSVFTNREPFGPVGFMKSAISIAEDE 124
Query: 603 KWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVEKLNKEAGT---FDCHDYMSECTVEIL 773
+W+ R L++PTF LK + + +V L +E T D +++++
Sbjct: 125 EWKRLRSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLRRERETGKPVTLKDVFGAYSMDVI 184
Query: 774 LETAMGVS 797
++ GV+
Sbjct: 185 TSSSFGVN 192
>EF122242-1|ABO41977.1| 321|Homo sapiens cytochrome P450 2F1
variant protein.
Length = 321
Score = 41.9 bits (94), Expect = 0.006
Identities = 35/134 (26%), Positives = 68/134 (50%), Gaps = 2/134 (1%)
Frame = +3
Query: 336 GPKGLPLIGNALEFVGGSAEIFSNIIQKSLAFDNESVVKIWIGPRLLVFLYDPRDV-EVI 512
GP+ LP++GN L S ++ +++ + S + S+ + +GPR +V L + V E +
Sbjct: 33 GPRPLPILGNLLLLC--SQDMLTSLTKLSKEYG--SMYTVHLGPRRVVVLSGYQAVKEAL 88
Query: 513 LSSHVHIDKADEY-RFFKPWLGNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANS 689
+ +Y FF GNG+ S+G +W+ R+ F + +L++ F
Sbjct: 89 VDQGEEFSGRGDYPAFFNFTKGNGIAFSSGDRWKVLRQ-----FSIQILRN----FGMGK 139
Query: 690 RAVVEKLNKEAGTF 731
R++ E++ +E G+F
Sbjct: 140 RSIEERILEE-GSF 152
>AY390425-1|AAQ92353.1| 503|Homo sapiens cytochrome P450 CYP3A43.1
protein.
Length = 503
Score = 41.1 bits (92), Expect = 0.010
Identities = 39/191 (20%), Positives = 85/191 (44%), Gaps = 7/191 (3%)
Frame = +3
Query: 246 YVLLVPAVILWYTYWRMSRRRLYELAEKLNGPKGLPLIGNALEFVGGSAEIFSNIIQKSL 425
+VL+ +++L Y Y S + +L + GP LP +G L ++ G N ++
Sbjct: 12 WVLVATSLVLLYIYGTHSHKLFKKLG--IPGPTPLPFLGTILFYLRG----LWNFDREC- 64
Query: 426 AFDNESVVKIW---IGPRLLVFLYDPRDVEVILSSHVHIDKADEYRFFKP-WLGNGLLIS 593
NE ++W G + ++ + DP ++ +L + ++ +L + L +
Sbjct: 65 ---NEKYGEMWGLYEGQQPMLVIMDPDMIKTVLVKECYSVFTNQMPLGPMGFLKSALSFA 121
Query: 594 TGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVEKLNKEA---GTFDCHDYMSECTV 764
++W+ R L++P F K + + + +V L +EA + + D+ T+
Sbjct: 122 EDEEWKRIRTLLSPAFTSVKFKEMVPIISQCGDMLVRSLRQEAENSKSINLKDFFGAYTM 181
Query: 765 EILLETAMGVS 797
+++ T GV+
Sbjct: 182 DVITGTLFGVN 192
>AY390424-1|AAQ92352.1| 503|Homo sapiens cytochrome P450 CYP3A43.3
protein.
Length = 503
Score = 41.1 bits (92), Expect = 0.010
Identities = 39/191 (20%), Positives = 85/191 (44%), Gaps = 7/191 (3%)
Frame = +3
Query: 246 YVLLVPAVILWYTYWRMSRRRLYELAEKLNGPKGLPLIGNALEFVGGSAEIFSNIIQKSL 425
+VL+ +++L Y Y S + +L + GP LP +G L ++ G N ++
Sbjct: 12 WVLVATSLVLLYIYGTHSHKLFKKLG--IPGPTPLPFLGTILFYLRG----LWNFDREC- 64
Query: 426 AFDNESVVKIW---IGPRLLVFLYDPRDVEVILSSHVHIDKADEYRFFKP-WLGNGLLIS 593
NE ++W G + ++ + DP ++ +L + ++ +L + L +
Sbjct: 65 ---NEKYGEMWGLYEGQQPMLVIMDPDMIKTVLVKECYSVFTNQMPLGPMGFLKSALSFA 121
Query: 594 TGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVEKLNKEA---GTFDCHDYMSECTV 764
++W+ R L++P F K + + + +V L +EA + + D+ T+
Sbjct: 122 EDEEWKRIRTLLSPAFTSVKFKEMVPIISQCGDMLVRSLRQEAENSKSINLKDFFGAYTM 181
Query: 765 EILLETAMGVS 797
+++ T GV+
Sbjct: 182 DVITGTLFGVN 192
>AF337813-1|AAK38841.1| 503|Homo sapiens cytochrome P450 subfamily
IIIA polypeptide 43 protein.
Length = 503
Score = 41.1 bits (92), Expect = 0.010
Identities = 39/191 (20%), Positives = 85/191 (44%), Gaps = 7/191 (3%)
Frame = +3
Query: 246 YVLLVPAVILWYTYWRMSRRRLYELAEKLNGPKGLPLIGNALEFVGGSAEIFSNIIQKSL 425
+VL+ +++L Y Y S + +L + GP LP +G L ++ G N ++
Sbjct: 12 WVLVATSLVLLYIYGTHSHKLFKKLG--IPGPTPLPFLGTILFYLRG----LWNFDREC- 64
Query: 426 AFDNESVVKIW---IGPRLLVFLYDPRDVEVILSSHVHIDKADEYRFFKP-WLGNGLLIS 593
NE ++W G + ++ + DP ++ +L + ++ +L + L +
Sbjct: 65 ---NEKYGEMWGLYEGQQPMLVIMDPDMIKTVLVKECYSVFTNQMPLGPMGFLKSALSFA 121
Query: 594 TGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVEKLNKEA---GTFDCHDYMSECTV 764
++W+ R L++P F K + + + +V L +EA + + D+ T+
Sbjct: 122 EDEEWKRIRTLLSPAFTSVKFKEMVPIISQCGDMLVRSLRQEAENSKSINLKDFFGAYTM 181
Query: 765 EILLETAMGVS 797
+++ T GV+
Sbjct: 182 DVITGTLFGVN 192
>AF319634-1|AAK00325.1| 503|Homo sapiens cytochrome P450 CYP3A43
protein.
Length = 503
Score = 41.1 bits (92), Expect = 0.010
Identities = 39/191 (20%), Positives = 85/191 (44%), Gaps = 7/191 (3%)
Frame = +3
Query: 246 YVLLVPAVILWYTYWRMSRRRLYELAEKLNGPKGLPLIGNALEFVGGSAEIFSNIIQKSL 425
+VL+ +++L Y Y S + +L + GP LP +G L ++ G N ++
Sbjct: 12 WVLVATSLVLLYIYGTHSHKLFKKLG--IPGPTPLPFLGTILFYLRG----LWNFDREC- 64
Query: 426 AFDNESVVKIW---IGPRLLVFLYDPRDVEVILSSHVHIDKADEYRFFKP-WLGNGLLIS 593
NE ++W G + ++ + DP ++ +L + ++ +L + L +
Sbjct: 65 ---NEKYGEMWGLYEGQQPMLVIMDPDMIKTVLVKECYSVFTNQMPLGPMGFLKSALSFA 121
Query: 594 TGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVEKLNKEA---GTFDCHDYMSECTV 764
++W+ R L++P F K + + + +V L +EA + + D+ T+
Sbjct: 122 EDEEWKRIRTLLSPAFTSVKFKEMVPIISQCGDMLVRSLRQEAENSKSINLKDFFGAYTM 181
Query: 765 EILLETAMGVS 797
+++ T GV+
Sbjct: 182 DVITGTLFGVN 192
>AF280111-1|AAG33012.1| 250|Homo sapiens cytochrome P450 subfamily
IIIA polypeptide 43 protein.
Length = 250
Score = 41.1 bits (92), Expect = 0.010
Identities = 39/191 (20%), Positives = 85/191 (44%), Gaps = 7/191 (3%)
Frame = +3
Query: 246 YVLLVPAVILWYTYWRMSRRRLYELAEKLNGPKGLPLIGNALEFVGGSAEIFSNIIQKSL 425
+VL+ +++L Y Y S + +L + GP LP +G L ++ G N ++
Sbjct: 12 WVLVATSLVLLYIYGTHSHKLFKKLG--IPGPTPLPFLGTILFYLRG----LWNFDREC- 64
Query: 426 AFDNESVVKIW---IGPRLLVFLYDPRDVEVILSSHVHIDKADEYRFFKP-WLGNGLLIS 593
NE ++W G + ++ + DP ++ +L + ++ +L + L +
Sbjct: 65 ---NEKYGEMWGLYEGQQPMLVIMDPDMIKTVLVKECYSVFTNQMPLGPMGFLKSALSFA 121
Query: 594 TGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVEKLNKEA---GTFDCHDYMSECTV 764
++W+ R L++P F K + + + +V L +EA + + D+ T+
Sbjct: 122 EDEEWKRIRTLLSPAFTSVKFKEMVPIISQCGDMLVRSLRQEAENSKSINLKDFFGAYTM 181
Query: 765 EILLETAMGVS 797
+++ T GV+
Sbjct: 182 DVITGTLFGVN 192
>AF280110-1|AAG33011.1| 420|Homo sapiens cytochrome P450 subfamily
IIIA polypeptide 43 protein.
Length = 420
Score = 41.1 bits (92), Expect = 0.010
Identities = 39/191 (20%), Positives = 85/191 (44%), Gaps = 7/191 (3%)
Frame = +3
Query: 246 YVLLVPAVILWYTYWRMSRRRLYELAEKLNGPKGLPLIGNALEFVGGSAEIFSNIIQKSL 425
+VL+ +++L Y Y S + +L + GP LP +G L ++ G N ++
Sbjct: 12 WVLVATSLVLLYIYGTHSHKLFKKLG--IPGPTPLPFLGTILFYLRG----LWNFDREC- 64
Query: 426 AFDNESVVKIW---IGPRLLVFLYDPRDVEVILSSHVHIDKADEYRFFKP-WLGNGLLIS 593
NE ++W G + ++ + DP ++ +L + ++ +L + L +
Sbjct: 65 ---NEKYGEMWGLYEGQQPMLVIMDPDMIKTVLVKECYSVFTNQMPLGPMGFLKSALSFA 121
Query: 594 TGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVEKLNKEA---GTFDCHDYMSECTV 764
++W+ R L++P F K + + + +V L +EA + + D+ T+
Sbjct: 122 EDEEWKRIRTLLSPAFTSVKFKEMVPIISQCGDMLVRSLRQEAENSKSINLKDFFGAYTM 181
Query: 765 EILLETAMGVS 797
+++ T GV+
Sbjct: 182 DVITGTLFGVN 192
>AF280109-1|AAG33010.1| 504|Homo sapiens cytochrome P450 subfamily
IIIA polypeptide 43 protein.
Length = 504
Score = 41.1 bits (92), Expect = 0.010
Identities = 39/191 (20%), Positives = 85/191 (44%), Gaps = 7/191 (3%)
Frame = +3
Query: 246 YVLLVPAVILWYTYWRMSRRRLYELAEKLNGPKGLPLIGNALEFVGGSAEIFSNIIQKSL 425
+VL+ +++L Y Y S + +L + GP LP +G L ++ G N ++
Sbjct: 12 WVLVATSLVLLYIYGTHSHKLFKKLG--IPGPTPLPFLGTILFYLRG----LWNFDREC- 64
Query: 426 AFDNESVVKIW---IGPRLLVFLYDPRDVEVILSSHVHIDKADEYRFFKP-WLGNGLLIS 593
NE ++W G + ++ + DP ++ +L + ++ +L + L +
Sbjct: 65 ---NEKYGEMWGLYEGQQPMLVIMDPDMIKTVLVKECYSVFTNQMPLGPMGFLKSALSFA 121
Query: 594 TGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVEKLNKEA---GTFDCHDYMSECTV 764
++W+ R L++P F K + + + +V L +EA + + D+ T+
Sbjct: 122 EDEEWKRIRTLLSPAFTSVKFKEMVPIISQCGDMLVRSLRQEAENSKSINLKDFFGAYTM 181
Query: 765 EILLETAMGVS 797
+++ T GV+
Sbjct: 182 DVITGTLFGVN 192
>AF280108-1|AAG33009.1| 503|Homo sapiens cytochrome P450 subfamily
IIIA polypeptide 43 protein.
Length = 503
Score = 41.1 bits (92), Expect = 0.010
Identities = 39/191 (20%), Positives = 85/191 (44%), Gaps = 7/191 (3%)
Frame = +3
Query: 246 YVLLVPAVILWYTYWRMSRRRLYELAEKLNGPKGLPLIGNALEFVGGSAEIFSNIIQKSL 425
+VL+ +++L Y Y S + +L + GP LP +G L ++ G N ++
Sbjct: 12 WVLVATSLVLLYIYGTHSHKLFKKLG--IPGPTPLPFLGTILFYLRG----LWNFDREC- 64
Query: 426 AFDNESVVKIW---IGPRLLVFLYDPRDVEVILSSHVHIDKADEYRFFKP-WLGNGLLIS 593
NE ++W G + ++ + DP ++ +L + ++ +L + L +
Sbjct: 65 ---NEKYGEMWGLYEGQQPMLVIMDPDMIKTVLVKECYSVFTNQMPLGPMGFLKSALSFA 121
Query: 594 TGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVEKLNKEA---GTFDCHDYMSECTV 764
++W+ R L++P F K + + + +V L +EA + + D+ T+
Sbjct: 122 EDEEWKRIRTLLSPAFTSVKFKEMVPIISQCGDMLVRSLRQEAENSKSINLKDFFGAYTM 181
Query: 765 EILLETAMGVS 797
+++ T GV+
Sbjct: 182 DVITGTLFGVN 192
>AC011904-5|AAS07394.1| 504|Homo sapiens unknown protein.
Length = 504
Score = 41.1 bits (92), Expect = 0.010
Identities = 39/191 (20%), Positives = 85/191 (44%), Gaps = 7/191 (3%)
Frame = +3
Query: 246 YVLLVPAVILWYTYWRMSRRRLYELAEKLNGPKGLPLIGNALEFVGGSAEIFSNIIQKSL 425
+VL+ +++L Y Y S + +L + GP LP +G L ++ G N ++
Sbjct: 12 WVLVATSLVLLYIYGTHSHKLFKKLG--IPGPTPLPFLGTILFYLRG----LWNFDREC- 64
Query: 426 AFDNESVVKIW---IGPRLLVFLYDPRDVEVILSSHVHIDKADEYRFFKP-WLGNGLLIS 593
NE ++W G + ++ + DP ++ +L + ++ +L + L +
Sbjct: 65 ---NEKYGEMWGLYEGQQPMLVIMDPDMIKTVLVKECYSVFTNQMPLGPMGFLKSALSFA 121
Query: 594 TGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVEKLNKEA---GTFDCHDYMSECTV 764
++W+ R L++P F K + + + +V L +EA + + D+ T+
Sbjct: 122 EDEEWKRIRTLLSPAFTSVKFKEMVPIISQCGDMLVRSLRQEAENSKSINLKDFFGAYTM 181
Query: 765 EILLETAMGVS 797
+++ T GV+
Sbjct: 182 DVITGTLFGVN 192
>AC011904-4|AAS07395.1| 503|Homo sapiens unknown protein.
Length = 503
Score = 41.1 bits (92), Expect = 0.010
Identities = 39/191 (20%), Positives = 85/191 (44%), Gaps = 7/191 (3%)
Frame = +3
Query: 246 YVLLVPAVILWYTYWRMSRRRLYELAEKLNGPKGLPLIGNALEFVGGSAEIFSNIIQKSL 425
+VL+ +++L Y Y S + +L + GP LP +G L ++ G N ++
Sbjct: 12 WVLVATSLVLLYIYGTHSHKLFKKLG--IPGPTPLPFLGTILFYLRG----LWNFDREC- 64
Query: 426 AFDNESVVKIW---IGPRLLVFLYDPRDVEVILSSHVHIDKADEYRFFKP-WLGNGLLIS 593
NE ++W G + ++ + DP ++ +L + ++ +L + L +
Sbjct: 65 ---NEKYGEMWGLYEGQQPMLVIMDPDMIKTVLVKECYSVFTNQMPLGPMGFLKSALSFA 121
Query: 594 TGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVEKLNKEA---GTFDCHDYMSECTV 764
++W+ R L++P F K + + + +V L +EA + + D+ T+
Sbjct: 122 EDEEWKRIRTLLSPAFTSVKFKEMVPIISQCGDMLVRSLRQEAENSKSINLKDFFGAYTM 181
Query: 765 EILLETAMGVS 797
+++ T GV+
Sbjct: 182 DVITGTLFGVN 192
>BC033691-1|AAH33691.1| 504|Homo sapiens cytochrome P450, family 2,
subfamily S, polypeptide 1 protein.
Length = 504
Score = 39.5 bits (88), Expect = 0.030
Identities = 41/166 (24%), Positives = 72/166 (43%), Gaps = 6/166 (3%)
Frame = +3
Query: 336 GPKGLPLIGNALEFVGGSAEIFSNIIQKSLAFDNESVVKIWIGP-RLLVFLYDPRDVEVI 512
GP LPL+GN L+ G+ ++S +++ S + V I++GP R +V L V
Sbjct: 35 GPTPLPLLGNLLQLRPGA--LYSGLMRLSKKYG--PVFTIYLGPWRPVVVLVGQEAVREA 90
Query: 513 LSSHVH--IDKADEYRFFKPWLGNGLLISTGQKWRSHRKLIAPTFH-LNVLK-SFIDLFN 680
L + + G+G+ S G++WR RK L + K +L
Sbjct: 91 LGGQAEEFSGRGTVAMLEGTFDGHGVFFSNGERWRQLRKFTMLALRDLGMGKREGEELIQ 150
Query: 681 ANSRAVVEKL-NKEAGTFDCHDYMSECTVEILLETAMGVSKTTQDQ 815
A +R +VE E FD +++ T ++ G+ + +D+
Sbjct: 151 AEARCLVETFQGTEGRPFDPSLLLAQATSNVVCSLLFGLRFSYEDK 196
>AY358603-1|AAQ88966.1| 504|Homo sapiens Cytochrome p450 protein.
Length = 504
Score = 39.5 bits (88), Expect = 0.030
Identities = 41/166 (24%), Positives = 72/166 (43%), Gaps = 6/166 (3%)
Frame = +3
Query: 336 GPKGLPLIGNALEFVGGSAEIFSNIIQKSLAFDNESVVKIWIGP-RLLVFLYDPRDVEVI 512
GP LPL+GN L+ G+ ++S +++ S + V I++GP R +V L V
Sbjct: 35 GPTPLPLLGNLLQLRPGA--LYSGLMRLSKKYG--PVFTIYLGPWRPVVVLVGQEAVREA 90
Query: 513 LSSHVH--IDKADEYRFFKPWLGNGLLISTGQKWRSHRKLIAPTFH-LNVLK-SFIDLFN 680
L + + G+G+ S G++WR RK L + K +L
Sbjct: 91 LGGQAEEFSGRGTVAMLEGTFDGHGVFFSNGERWRQLRKFTMLALRDLGMGKREGEELIQ 150
Query: 681 ANSRAVVEKL-NKEAGTFDCHDYMSECTVEILLETAMGVSKTTQDQ 815
A +R +VE E FD +++ T ++ G+ + +D+
Sbjct: 151 AEARCLVETFQGTEGRPFDPSLLLAQATSNVVCSLLFGLRFSYEDK 196
>AK027605-1|BAB55227.1| 564|Homo sapiens protein ( Homo sapiens
cDNA FLJ14699 fis, clone NT2RP2006571, moderately
similar to CYTOCHROME P450 2G1 (EC 1.14.14.1). ).
Length = 564
Score = 39.5 bits (88), Expect = 0.030
Identities = 41/166 (24%), Positives = 72/166 (43%), Gaps = 6/166 (3%)
Frame = +3
Query: 336 GPKGLPLIGNALEFVGGSAEIFSNIIQKSLAFDNESVVKIWIGP-RLLVFLYDPRDVEVI 512
GP LPL+GN L+ G+ ++S +++ S + V I++GP R +V L V
Sbjct: 35 GPTPLPLLGNLLQLRPGA--LYSGLMRLSKKYG--PVFTIYLGPWRPVVVLVGQEAVREA 90
Query: 513 LSSHVH--IDKADEYRFFKPWLGNGLLISTGQKWRSHRKLIAPTFH-LNVLK-SFIDLFN 680
L + + G+G+ S G++WR RK L + K +L
Sbjct: 91 LGGQAEEFSGRGTVAMLEGTFDGHGVFFSNGERWRQLRKFTMLALRDLGMGKREGEELIQ 150
Query: 681 ANSRAVVEKL-NKEAGTFDCHDYMSECTVEILLETAMGVSKTTQDQ 815
A +R +VE E FD +++ T ++ G+ + +D+
Sbjct: 151 AEARCLVETFQGTEGRPFDPSLLLAQATSNVVCSLLFGLRFSYEDK 196
>AF335278-1|AAK13498.1| 504|Homo sapiens cytochrome P450 2S1
protein.
Length = 504
Score = 39.5 bits (88), Expect = 0.030
Identities = 41/166 (24%), Positives = 72/166 (43%), Gaps = 6/166 (3%)
Frame = +3
Query: 336 GPKGLPLIGNALEFVGGSAEIFSNIIQKSLAFDNESVVKIWIGP-RLLVFLYDPRDVEVI 512
GP LPL+GN L+ G+ ++S +++ S + V I++GP R +V L V
Sbjct: 35 GPTPLPLLGNLLQLRPGA--LYSGLMRLSKKYG--PVFTIYLGPWRPVVVLVGQEAVREA 90
Query: 513 LSSHVH--IDKADEYRFFKPWLGNGLLISTGQKWRSHRKLIAPTFH-LNVLK-SFIDLFN 680
L + + G+G+ S G++WR RK L + K +L
Sbjct: 91 LGGQAEEFSGRGTVAMLEGTFDGHGVFFSNGERWRQLRKFTMLALRDLGMGKREGEELIQ 150
Query: 681 ANSRAVVEKL-NKEAGTFDCHDYMSECTVEILLETAMGVSKTTQDQ 815
A +R +VE E FD +++ T ++ G+ + +D+
Sbjct: 151 AEARCLVETFQGTEGRPFDPSLLLAQATSNVVCSLLFGLRFSYEDK 196
>J04813-1|AAA02993.1| 502|Homo sapiens cytochrome P450 PCN3
protein.
Length = 502
Score = 38.7 bits (86), Expect = 0.052
Identities = 38/189 (20%), Positives = 80/189 (42%), Gaps = 5/189 (2%)
Frame = +3
Query: 246 YVLLVPAVILWYTYWRMSRRRLYELAEKLNGPKGLPLIGNALEFVGGSAEIFSNIIQKSL 425
++LL +++L Y Y + L + GP LPL+GN L + G + + +K
Sbjct: 12 WLLLAVSLVLLYLYGTRTHGLFKRLG--IPGPTPLPLLGNVLSYRQGLWKFDTECYKKY- 68
Query: 426 AFDNESVVKIWIGPRLLVFLYDPRDVEVILSSHVHIDKADEYRFFKP--WLGNGLLISTG 599
+ + G ++ + DP + +L + + R P ++ + + ++
Sbjct: 69 ----GKMWGTYEGQLPVLAITDPDVIRTVLVKECYSVFTNR-RSLGPVGFMKSAISLAED 123
Query: 600 QKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVEKLNKEA---GTFDCHDYMSECTVEI 770
++W+ R L++PTF LK + +V L +EA D ++++
Sbjct: 124 EEWKRIRSLLSPTFTSGKLKEMFPIIAQYGDVLVRNLRREAEKGKPVTLKDIFGAYSMDV 183
Query: 771 LLETAMGVS 797
+ T+ GV+
Sbjct: 184 ITGTSFGVN 192
>J02906-1|AAA52156.1| 491|Homo sapiens CYP2F1 protein.
Length = 491
Score = 38.7 bits (86), Expect = 0.052
Identities = 34/134 (25%), Positives = 67/134 (50%), Gaps = 2/134 (1%)
Frame = +3
Query: 336 GPKGLPLIGNALEFVGGSAEIFSNIIQKSLAFDNESVVKIWIGPRLLVFLYDPRDV-EVI 512
GP+ L ++GN L S ++ +++ + S + S+ + +GPR +V L + V E +
Sbjct: 33 GPRPLSILGNLLLLC--SQDMLTSLTKLSKEYG--SMYTVHLGPRRVVVLSGYQAVKEAL 88
Query: 513 LSSHVHIDKADEY-RFFKPWLGNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANS 689
+ +Y FF GNG+ S+G +W+ R+ F + +L++ F
Sbjct: 89 VDQGEEFSGRGDYPAFFNFTKGNGIAFSSGDRWKVLRQ-----FSIQILRN----FGMGK 139
Query: 690 RAVVEKLNKEAGTF 731
R++ E++ +E G+F
Sbjct: 140 RSIEERILEE-GSF 152
>EF122241-1|ABO41976.1| 491|Homo sapiens cytochrome P450 2F1
variant protein.
Length = 491
Score = 38.7 bits (86), Expect = 0.052
Identities = 34/134 (25%), Positives = 67/134 (50%), Gaps = 2/134 (1%)
Frame = +3
Query: 336 GPKGLPLIGNALEFVGGSAEIFSNIIQKSLAFDNESVVKIWIGPRLLVFLYDPRDV-EVI 512
GP+ L ++GN L S ++ +++ + S + S+ + +GPR +V L + V E +
Sbjct: 33 GPRPLSILGNLLLLC--SQDMLTSLTKLSKEYG--SMYTVHLGPRRVVVLSGYQAVKEAL 88
Query: 513 LSSHVHIDKADEY-RFFKPWLGNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANS 689
+ +Y FF GNG+ S+G +W+ R+ F + +L++ F
Sbjct: 89 VDQGEEFSGRGDYPAFFNFTKGNGIAFSSGDRWKVLRQ-----FSIQILRN----FGMGK 139
Query: 690 RAVVEKLNKEAGTF 731
R++ E++ +E G+F
Sbjct: 140 RSIEERILEE-GSF 152
>DQ680079-1|ABG25922.1| 347|Homo sapiens truncated cytochrome P450,
family 3, subfamily A, polypeptide 5 protein.
Length = 347
Score = 38.7 bits (86), Expect = 0.052
Identities = 38/189 (20%), Positives = 80/189 (42%), Gaps = 5/189 (2%)
Frame = +3
Query: 246 YVLLVPAVILWYTYWRMSRRRLYELAEKLNGPKGLPLIGNALEFVGGSAEIFSNIIQKSL 425
++LL +++L Y Y + L + GP LPL+GN L + G + + +K
Sbjct: 12 WLLLAVSLVLLYLYGTRTHGLFKRLG--IPGPTPLPLLGNVLSYRQGLWKFDTECYKKY- 68
Query: 426 AFDNESVVKIWIGPRLLVFLYDPRDVEVILSSHVHIDKADEYRFFKP--WLGNGLLISTG 599
+ + G ++ + DP + +L + + R P ++ + + ++
Sbjct: 69 ----GKMWGTYEGQLPVLAITDPDVIRTVLVKECYSVFTNR-RSLGPVGFMKSAISLAED 123
Query: 600 QKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVEKLNKEA---GTFDCHDYMSECTVEI 770
++W+ R L++PTF LK + +V L +EA D ++++
Sbjct: 124 EEWKRIRSLLSPTFTSGKLKEMFPIIAQYGDVLVRNLRREAEKGKPVTLKDIFGAYSMDV 183
Query: 771 LLETAMGVS 797
+ T+ GV+
Sbjct: 184 ITGTSFGVN 192
>BC109056-1|AAI09057.1| 320|Homo sapiens CYP2F1 protein protein.
Length = 320
Score = 38.7 bits (86), Expect = 0.052
Identities = 34/134 (25%), Positives = 67/134 (50%), Gaps = 2/134 (1%)
Frame = +3
Query: 336 GPKGLPLIGNALEFVGGSAEIFSNIIQKSLAFDNESVVKIWIGPRLLVFLYDPRDV-EVI 512
GP+ L ++GN L S ++ +++ + S + S+ + +GPR +V L + V E +
Sbjct: 33 GPRPLSILGNLLLLC--SQDMLTSLTKLSKEYG--SMYTVHLGPRRVVVLSGYQAVKEAL 88
Query: 513 LSSHVHIDKADEY-RFFKPWLGNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANS 689
+ +Y FF GNG+ S+G +W+ R+ F + +L++ F
Sbjct: 89 VDQGEEFSGRGDYPAFFNFTKGNGIAFSSGDRWKVLRQ-----FSIQILRN----FGMGK 139
Query: 690 RAVVEKLNKEAGTF 731
R++ E++ +E G+F
Sbjct: 140 RSIEERILEE-GSF 152
>BC033862-1|AAH33862.1| 502|Homo sapiens cytochrome P450, family 3,
subfamily A, polypeptide 5 protein.
Length = 502
Score = 38.7 bits (86), Expect = 0.052
Identities = 38/189 (20%), Positives = 80/189 (42%), Gaps = 5/189 (2%)
Frame = +3
Query: 246 YVLLVPAVILWYTYWRMSRRRLYELAEKLNGPKGLPLIGNALEFVGGSAEIFSNIIQKSL 425
++LL +++L Y Y + L + GP LPL+GN L + G + + +K
Sbjct: 12 WLLLAVSLVLLYLYGTRTHGLFKRLG--IPGPTPLPLLGNVLSYRQGLWKFDTECYKKY- 68
Query: 426 AFDNESVVKIWIGPRLLVFLYDPRDVEVILSSHVHIDKADEYRFFKP--WLGNGLLISTG 599
+ + G ++ + DP + +L + + R P ++ + + ++
Sbjct: 69 ----GKMWGTYEGQLPVLAITDPDVIRTVLVKECYSVFTNR-RSLGPVGFMKSAISLAED 123
Query: 600 QKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVEKLNKEA---GTFDCHDYMSECTVEI 770
++W+ R L++PTF LK + +V L +EA D ++++
Sbjct: 124 EEWKRIRSLLSPTFTSGKLKEMFPIIAQYGDVLVRNLRREAEKGKPVTLKDIFGAYSMDV 183
Query: 771 LLETAMGVS 797
+ T+ GV+
Sbjct: 184 ITGTSFGVN 192
>AF372573-1|AAL69652.1| 495|Homo sapiens cytochrome P450 2F1
protein.
Length = 495
Score = 38.7 bits (86), Expect = 0.052
Identities = 34/134 (25%), Positives = 67/134 (50%), Gaps = 2/134 (1%)
Frame = +3
Query: 336 GPKGLPLIGNALEFVGGSAEIFSNIIQKSLAFDNESVVKIWIGPRLLVFLYDPRDV-EVI 512
GP+ L ++GN L S ++ +++ + S + S+ + +GPR +V L + V E +
Sbjct: 33 GPRPLSILGNLLLLC--SQDMLTSLTKLSKEYG--SMYTVHLGPRRVVVLSGYQAVKEAL 88
Query: 513 LSSHVHIDKADEY-RFFKPWLGNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANS 689
+ +Y FF GNG+ S+G +W+ R+ F + +L++ F
Sbjct: 89 VDQGEEFSGRGDYPAFFNFTKGNGIAFSSGDRWKVLRQ-----FSIQILRN----FGMGK 139
Query: 690 RAVVEKLNKEAGTF 731
R++ E++ +E G+F
Sbjct: 140 RSIEERILEE-GSF 152
>AC005020-1|AAS02016.1| 502|Homo sapiens unknown protein.
Length = 502
Score = 38.7 bits (86), Expect = 0.052
Identities = 38/189 (20%), Positives = 80/189 (42%), Gaps = 5/189 (2%)
Frame = +3
Query: 246 YVLLVPAVILWYTYWRMSRRRLYELAEKLNGPKGLPLIGNALEFVGGSAEIFSNIIQKSL 425
++LL +++L Y Y + L + GP LPL+GN L + G + + +K
Sbjct: 12 WLLLAVSLVLLYLYGTRTHGLFKRLG--IPGPTPLPLLGNVLSYRQGLWKFDTECYKKY- 68
Query: 426 AFDNESVVKIWIGPRLLVFLYDPRDVEVILSSHVHIDKADEYRFFKP--WLGNGLLISTG 599
+ + G ++ + DP + +L + + R P ++ + + ++
Sbjct: 69 ----GKMWGTYEGQLPVLAITDPDVIRTVLVKECYSVFTNR-RSLGPVGFMKSAISLAED 123
Query: 600 QKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVEKLNKEA---GTFDCHDYMSECTVEI 770
++W+ R L++PTF LK + +V L +EA D ++++
Sbjct: 124 EEWKRIRSLLSPTFTSGKLKEMFPIIAQYGDVLVRNLRREAEKGKPVTLKDIFGAYSMDV 183
Query: 771 LLETAMGVS 797
+ T+ GV+
Sbjct: 184 ITGTSFGVN 192
>AK223008-1|BAD96728.1| 502|Homo sapiens cytochrome P450, family 3,
subfamily A, polypeptide 5 variant protein.
Length = 502
Score = 38.3 bits (85), Expect = 0.069
Identities = 38/189 (20%), Positives = 80/189 (42%), Gaps = 5/189 (2%)
Frame = +3
Query: 246 YVLLVPAVILWYTYWRMSRRRLYELAEKLNGPKGLPLIGNALEFVGGSAEIFSNIIQKSL 425
++LL +++L Y Y + L + GP LPL+GN L + G + + +K
Sbjct: 12 WLLLAVSLVLLYLYGTRTHGLFKRLG--IPGPTPLPLLGNVLSYRQGLWKFDTECYKKY- 68
Query: 426 AFDNESVVKIWIGPRLLVFLYDPRDVEVILSSHVHIDKADEYRFFKP--WLGNGLLISTG 599
+ + G ++ + DP + +L + + R P ++ + + ++
Sbjct: 69 ----GKMWGTYEGQLPVLAITDPDVIRTVLVKECYSVFTNR-RSLGPVGFMKSAISLAED 123
Query: 600 QKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVEKLNKEA---GTFDCHDYMSECTVEI 770
++W+ R L++PTF LK + +V L +EA D ++++
Sbjct: 124 EEWKRIRPLLSPTFTSGKLKEMFPIIAQYGDVLVRNLRREAEKGKPVTLKDIFGAYSMDV 183
Query: 771 LLETAMGVS 797
+ T+ GV+
Sbjct: 184 ITGTSFGVN 192
>BC070317-1|AAH70317.1| 162|Homo sapiens CYP2C9 protein protein.
Length = 162
Score = 37.9 bits (84), Expect = 0.091
Identities = 45/172 (26%), Positives = 76/172 (44%), Gaps = 9/172 (5%)
Frame = +3
Query: 237 NLFYVLLVPAVILWYTYWRMSRRRLYELAEKLNGPKGLPLIGNALEFVGGSAEIFSNIIQ 416
+L ++L + +L + WR S R + GP LP+IGN L+ G +I ++
Sbjct: 3 SLVVLVLCLSCLLLLSLWRQSSGR----GKLPPGPTPLPVIGNILQI--GIKDISKSLTN 56
Query: 417 KSLAFDNESVVKIWIGPRLLVFLYDPRDVEVILSSHVHIDKADEY--RFFKPWL-----G 575
S + V ++ G + +V L+ V+ L ID +E+ R P G
Sbjct: 57 LSKVYG--PVFTLYFGLKPIVVLHGYEAVKEAL-----IDLGEEFSGRGIFPLAERANRG 109
Query: 576 NGLLISTGQKWRSHRKLIAPTFHLNVL--KSFIDLFNANSRAVVEKLNKEAG 725
G++ S G+KW+ R+ T + +S D +R +VE+L K G
Sbjct: 110 FGIVFSNGKKWKEIRRFSLMTLRNFGMGKRSIEDCVQEEARCLVEELRKTKG 161
>BC020754-1|AAH20754.1| 162|Homo sapiens CYP2C9 protein protein.
Length = 162
Score = 37.5 bits (83), Expect = 0.12
Identities = 45/172 (26%), Positives = 76/172 (44%), Gaps = 9/172 (5%)
Frame = +3
Query: 237 NLFYVLLVPAVILWYTYWRMSRRRLYELAEKLNGPKGLPLIGNALEFVGGSAEIFSNIIQ 416
+L ++L + +L + WR S R + GP LP+IGN L+ G +I ++
Sbjct: 3 SLVVLVLCLSCLLLLSLWRQSSGR----GKLPPGPTPLPVIGNILQI--GIKDISKSLTN 56
Query: 417 KSLAFDNESVVKIWIGPRLLVFLYDPRDVEVILSSHVHIDKADEY--RFFKPWL-----G 575
S + V ++ G + +V L+ V+ L ID +E+ R P G
Sbjct: 57 LSKVYG--PVFTLYFGLKPIVVLHGYEAVKEAL-----IDLGEEFSGRGIFPLAERANRG 109
Query: 576 NGLLISTGQKWRSHRKLIAPTFHLNVL--KSFIDLFNANSRAVVEKLNKEAG 725
G++ S G+KW+ R+ T + +S D +R +VE+L K G
Sbjct: 110 FGIVFSNGKKWKEIRRFSLMTLRNFGMGKRSIEDRVQEEARCLVEELRKTKG 161
>U22028-1|AAB40519.1| 494|Homo sapiens cytochrome P450 protein.
Length = 494
Score = 36.3 bits (80), Expect = 0.28
Identities = 38/168 (22%), Positives = 77/168 (45%), Gaps = 2/168 (1%)
Frame = +3
Query: 228 SAINLFYVLLVPAVILWYTYWRMSRRRLYELAEKLNGPKGLPLIGNALEFVGGSAEIFSN 407
S + L +L V++ + WR + R + GP LP IGN L+ + +++++
Sbjct: 4 SGLLLVTLLACLTVMVLMSVWRQRKSR----GKLPPGPTPLPFIGNYLQL--NTEQMYNS 57
Query: 408 IIQKSLAFDNESVVKIWIGPRLLVFL--YDPRDVEVILSSHVHIDKADEYRFFKPWLGNG 581
+++ S + V I +GPR +V L +D ++ + + ++ F + G G
Sbjct: 58 LMKISERYG--PVFTIHLGPRRVVVLCGHDAVKEALVDQAEEFSGRGEQATFDWLFKGYG 115
Query: 582 LLISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVEKLNKEAG 725
+ S G++ + R+ F + L+ F R + E++ +EAG
Sbjct: 116 VAFSNGERAKQLRR-----FSIATLRG----FGVGKRGIEERIQEEAG 154
>AY513609-1|AAR90940.1| 494|Homo sapiens cytochrome P450 2A13
variant 6 protein.
Length = 494
Score = 36.3 bits (80), Expect = 0.28
Identities = 38/168 (22%), Positives = 77/168 (45%), Gaps = 2/168 (1%)
Frame = +3
Query: 228 SAINLFYVLLVPAVILWYTYWRMSRRRLYELAEKLNGPKGLPLIGNALEFVGGSAEIFSN 407
S + L +L V++ + WR + R + GP LP IGN L+ + +++++
Sbjct: 4 SGLLLVTLLACLTVMVLMSVWRQRKSR----GKLPPGPTPLPFIGNYLQL--NTEQMYNS 57
Query: 408 IIQKSLAFDNESVVKIWIGPRLLVFL--YDPRDVEVILSSHVHIDKADEYRFFKPWLGNG 581
+++ S + V I +GPR +V L +D ++ + + ++ F + G G
Sbjct: 58 LMKISERYG--PVFTIHLGPRRVVVLCGHDAVKEALVDQAEEFSGRGEQATFDWLFKGYG 115
Query: 582 LLISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVEKLNKEAG 725
+ S G++ + R+ F + L+ F R + E++ +EAG
Sbjct: 116 VAFSNGERAKQLRR-----FSIATLRG----FGVGKRGIEERIQEEAG 154
>AY513608-1|AAR90939.1| 494|Homo sapiens cytochrome P450 2A13
variant 5 protein.
Length = 494
Score = 36.3 bits (80), Expect = 0.28
Identities = 38/168 (22%), Positives = 77/168 (45%), Gaps = 2/168 (1%)
Frame = +3
Query: 228 SAINLFYVLLVPAVILWYTYWRMSRRRLYELAEKLNGPKGLPLIGNALEFVGGSAEIFSN 407
S + L +L V++ + WR + R + GP LP IGN L+ + +++++
Sbjct: 4 SGLLLVTLLACLTVMVLMSVWRQRKSR----GKLPPGPTPLPFIGNYLQL--NTEQMYNS 57
Query: 408 IIQKSLAFDNESVVKIWIGPRLLVFL--YDPRDVEVILSSHVHIDKADEYRFFKPWLGNG 581
+++ S + V I +GPR +V L +D ++ + + ++ F + G G
Sbjct: 58 LMKISERYG--PVFTIHLGPRRVVVLCGHDAVKEALVDQAEEFSGRGEQATFDWLFKGYG 115
Query: 582 LLISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVEKLNKEAG 725
+ S G++ + R+ F + L+ F R + E++ +EAG
Sbjct: 116 VAFSNGERAKQLRR-----FSIATLRG----FGVGKRGIEERIQEEAG 154
>AY513606-1|AAR90937.1| 494|Homo sapiens cytochrome P450 2A13
variant 3 protein.
Length = 494
Score = 36.3 bits (80), Expect = 0.28
Identities = 38/168 (22%), Positives = 77/168 (45%), Gaps = 2/168 (1%)
Frame = +3
Query: 228 SAINLFYVLLVPAVILWYTYWRMSRRRLYELAEKLNGPKGLPLIGNALEFVGGSAEIFSN 407
S + L +L V++ + WR + R + GP LP IGN L+ + +++++
Sbjct: 4 SGLLLVTLLACLTVMVLMSVWRQRKSR----GKLPPGPTPLPFIGNYLQL--NTEQMYNS 57
Query: 408 IIQKSLAFDNESVVKIWIGPRLLVFL--YDPRDVEVILSSHVHIDKADEYRFFKPWLGNG 581
+++ S + V I +GPR +V L +D ++ + + ++ F + G G
Sbjct: 58 LMKISERYG--PVFTIHLGPRRVVVLCGHDAVKEALVDQAEEFSGRGEQATFDWLFKGYG 115
Query: 582 LLISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVEKLNKEAG 725
+ S G++ + R+ F + L+ F R + E++ +EAG
Sbjct: 116 VAFSNGERAKQLRR-----FSIATLRG----FGVGKRGIEERIQEEAG 154
>AY513605-1|AAR90936.1| 494|Homo sapiens cytochrome P450 2A13
variant 2 protein.
Length = 494
Score = 36.3 bits (80), Expect = 0.28
Identities = 38/168 (22%), Positives = 77/168 (45%), Gaps = 2/168 (1%)
Frame = +3
Query: 228 SAINLFYVLLVPAVILWYTYWRMSRRRLYELAEKLNGPKGLPLIGNALEFVGGSAEIFSN 407
S + L +L V++ + WR + R + GP LP IGN L+ + +++++
Sbjct: 4 SGLLLVTLLACLTVMVLMSVWRQRKSR----GKLPPGPTPLPFIGNYLQL--NTEQMYNS 57
Query: 408 IIQKSLAFDNESVVKIWIGPRLLVFL--YDPRDVEVILSSHVHIDKADEYRFFKPWLGNG 581
+++ S + V I +GPR +V L +D ++ + + ++ F + G G
Sbjct: 58 LMKISERYG--PVFTIHLGPRRVVVLCGHDAVKEALVDQAEEFSGRGEQATFDWLFKGYG 115
Query: 582 LLISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVEKLNKEAG 725
+ S G++ + R+ F + L+ F R + E++ +EAG
Sbjct: 116 VAFSNGERAKQLRR-----FSIATLRG----FGVGKRGIEERIQEEAG 154
>AY513604-1|AAR90935.1| 494|Homo sapiens cytochrome P450 2A13
variant 1 protein.
Length = 494
Score = 36.3 bits (80), Expect = 0.28
Identities = 38/168 (22%), Positives = 77/168 (45%), Gaps = 2/168 (1%)
Frame = +3
Query: 228 SAINLFYVLLVPAVILWYTYWRMSRRRLYELAEKLNGPKGLPLIGNALEFVGGSAEIFSN 407
S + L +L V++ + WR + R + GP LP IGN L+ + +++++
Sbjct: 4 SGLLLVTLLACLTVMVLMSVWRQRKSR----GKLPPGPTPLPFIGNYLQL--NTEQMYNS 57
Query: 408 IIQKSLAFDNESVVKIWIGPRLLVFL--YDPRDVEVILSSHVHIDKADEYRFFKPWLGNG 581
+++ S + V I +GPR +V L +D ++ + + ++ F + G G
Sbjct: 58 LMKISERYG--PVFTIHLGPRRVVVLCGHDAVKEALVDQAEEFSGRGEQATFDWLFKGYG 115
Query: 582 LLISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVEKLNKEAG 725
+ S G++ + R+ F + L+ F R + E++ +EAG
Sbjct: 116 VAFSNGERAKQLRR-----FSIATLRG----FGVGKRGIEERIQEEAG 154
>AJ563376-2|CAD91645.1| 430|Homo sapiens cytochrome P450 protein.
Length = 430
Score = 36.3 bits (80), Expect = 0.28
Identities = 25/117 (21%), Positives = 55/117 (47%), Gaps = 5/117 (4%)
Frame = +3
Query: 462 GPRLLVFLYDPRDVEVILSSHVHIDKADEYRFFKP--WLGNGLLISTGQKWRSHRKLIAP 635
G + ++ + DP ++ +L + + R F P ++ + + I+ ++W+ R L++P
Sbjct: 4 GQQPVLAITDPDMIKTVLVKECYSVFTNR-RPFGPVGFMKSAISIAEDEEWKRLRSLLSP 62
Query: 636 TFHLNVLKSFIDLFNANSRAVVEKLNKEAGT---FDCHDYMSECTVEILLETAMGVS 797
TF LK + + +V L +EA T D +++++ T+ GV+
Sbjct: 63 TFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDVITSTSFGVN 119
>AF209774-1|AAG35775.1| 494|Homo sapiens cytochrome P450 2A13
protein.
Length = 494
Score = 36.3 bits (80), Expect = 0.28
Identities = 38/168 (22%), Positives = 77/168 (45%), Gaps = 2/168 (1%)
Frame = +3
Query: 228 SAINLFYVLLVPAVILWYTYWRMSRRRLYELAEKLNGPKGLPLIGNALEFVGGSAEIFSN 407
S + L +L V++ + WR + R + GP LP IGN L+ + +++++
Sbjct: 4 SGLLLVTLLACLTVMVLMSVWRQRKSR----GKLPPGPTPLPFIGNYLQL--NTEQMYNS 57
Query: 408 IIQKSLAFDNESVVKIWIGPRLLVFL--YDPRDVEVILSSHVHIDKADEYRFFKPWLGNG 581
+++ S + V I +GPR +V L +D ++ + + ++ F + G G
Sbjct: 58 LMKISERYG--PVFTIHLGPRRVVVLCGHDAVKEALVDQAEEFSGRGEQATFDWLFKGYG 115
Query: 582 LLISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVEKLNKEAG 725
+ S G++ + R+ F + L+ F R + E++ +EAG
Sbjct: 116 VAFSNGERAKQLRR-----FSIATLRG----FGVGKRGIEERIQEEAG 154
>X13930-1|CAA32118.1| 494|Homo sapiens protein ( Human CYP2A4 mRNA
for P-450 IIA4 protein. ).
Length = 494
Score = 35.9 bits (79), Expect = 0.37
Identities = 33/138 (23%), Positives = 66/138 (47%), Gaps = 3/138 (2%)
Frame = +3
Query: 336 GPKGLPLIGNALEFVGGSAEIFSNIIQKSLAFDNESVVKIWIGPRLLVFL--YDPRDVEV 509
GP LP IGN L+ + ++++++++ S + V I +GPR +V L +D +
Sbjct: 36 GPTPLPFIGNYLQL--NTEQMYNSLMKISERYG--PVFTIHLGPRRVVVLCGHDAVREAL 91
Query: 510 ILSSHVHIDKADEYRFFKPWLGNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANS 689
+ + + ++ F + G G++ S G++ + R+ F + L+ F
Sbjct: 92 VDQAEEFSGRGEQATFDWVFKGYGVVFSNGERAKQLRR-----FSIATLRD----FGVGK 142
Query: 690 RAVVEKLNKEAG-TFDCH 740
R + E++ +EAG D H
Sbjct: 143 RGIEERIQEEAGFLIDAH 160
>L16880-1|AAD13466.1| 273|Homo sapiens cytochrome P-450 2C protein.
Length = 273
Score = 35.9 bits (79), Expect = 0.37
Identities = 44/169 (26%), Positives = 75/169 (44%), Gaps = 9/169 (5%)
Frame = +3
Query: 237 NLFYVLLVPAVILWYTYWRMSRRRLYELAEKLNGPKGLPLIGNALEFVGGSAEIFSNIIQ 416
+L ++L + +L + WR S R + GP LP+IGN L+ G +I ++
Sbjct: 3 SLVVLVLCLSCLLLLSLWRQSSGR----GKLPPGPTPLPVIGNILQI--GIKDISKSLTN 56
Query: 417 KSLAFDNESVVKIWIGPRLLVFLYDPRDVEVILSSHVHIDKADEY--RFFKPWL-----G 575
S + V ++ G + +V L+ V+ L ID +E+ R P G
Sbjct: 57 LSKVYG--PVFTLYFGLKPIVVLHGYEAVKEAL-----IDLGEEFSGRGIFPLAERANRG 109
Query: 576 NGLLISTGQKWRSHRKLIAPTFHLNVL--KSFIDLFNANSRAVVEKLNK 716
G++ S G+KW+ R+ T + +S D +R +VE+L K
Sbjct: 110 FGIVFSNGKKWKEIRRFSLMTLRNFGMGKRSIEDRVQEEARCLVEELRK 158
>BC125054-1|AAI25055.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 9 protein.
Length = 490
Score = 35.9 bits (79), Expect = 0.37
Identities = 44/169 (26%), Positives = 75/169 (44%), Gaps = 9/169 (5%)
Frame = +3
Query: 237 NLFYVLLVPAVILWYTYWRMSRRRLYELAEKLNGPKGLPLIGNALEFVGGSAEIFSNIIQ 416
+L ++L + +L + WR S R + GP LP+IGN L+ G +I ++
Sbjct: 3 SLVVLVLCLSCLLLLSLWRQSSGR----GKLPPGPTPLPVIGNILQI--GIKDISKSLTN 56
Query: 417 KSLAFDNESVVKIWIGPRLLVFLYDPRDVEVILSSHVHIDKADEY--RFFKPWL-----G 575
S + V ++ G + +V L+ V+ L ID +E+ R P G
Sbjct: 57 LSKVYG--PVFTLYFGLKPIVVLHGYEAVKEAL-----IDLGEEFSGRGIFPLAERANRG 109
Query: 576 NGLLISTGQKWRSHRKLIAPTFHLNVL--KSFIDLFNANSRAVVEKLNK 716
G++ S G+KW+ R+ T + +S D +R +VE+L K
Sbjct: 110 FGIVFSNGKKWKEIRRFSLMTLRNFGMGKRSIEDRVQEEARCLVEELRK 158
>BC096255-1|AAH96255.1| 494|Homo sapiens cytochrome P450, family 2,
subfamily A, polypeptide 6 protein.
Length = 494
Score = 35.9 bits (79), Expect = 0.37
Identities = 33/138 (23%), Positives = 66/138 (47%), Gaps = 3/138 (2%)
Frame = +3
Query: 336 GPKGLPLIGNALEFVGGSAEIFSNIIQKSLAFDNESVVKIWIGPRLLVFL--YDPRDVEV 509
GP LP IGN L+ + ++++++++ S + V I +GPR +V L +D +
Sbjct: 36 GPTPLPFIGNYLQL--NTEQMYNSLMKISERYG--PVFTIHLGPRRVVVLCGHDAVREAL 91
Query: 510 ILSSHVHIDKADEYRFFKPWLGNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANS 689
+ + + ++ F + G G++ S G++ + R+ F + L+ F
Sbjct: 92 VDQAEEFSGRGEQATFDWVFKGYGVVFSNGERAKQLRR-----FSIATLRD----FGVGK 142
Query: 690 RAVVEKLNKEAG-TFDCH 740
R + E++ +EAG D H
Sbjct: 143 RGIEERIQEEAGFLIDAH 160
>AY702706-1|AAT94065.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 9 protein.
Length = 490
Score = 35.9 bits (79), Expect = 0.37
Identities = 44/169 (26%), Positives = 75/169 (44%), Gaps = 9/169 (5%)
Frame = +3
Query: 237 NLFYVLLVPAVILWYTYWRMSRRRLYELAEKLNGPKGLPLIGNALEFVGGSAEIFSNIIQ 416
+L ++L + +L + WR S R + GP LP+IGN L+ G +I ++
Sbjct: 3 SLVVLVLCLSCLLLLSLWRQSSGR----GKLPPGPTPLPVIGNILQI--GIKDISKSLTN 56
Query: 417 KSLAFDNESVVKIWIGPRLLVFLYDPRDVEVILSSHVHIDKADEY--RFFKPWL-----G 575
S + V ++ G + +V L+ V+ L ID +E+ R P G
Sbjct: 57 LSKVYG--PVFTLYFGLKPIVVLHGYEAVKEAL-----IDLGEEFSGRGIFPLAERANRG 109
Query: 576 NGLLISTGQKWRSHRKLIAPTFHLNVL--KSFIDLFNANSRAVVEKLNK 716
G++ S G+KW+ R+ T + +S D +R +VE+L K
Sbjct: 110 FGIVFSNGKKWKEIRRFSLMTLRNFGMGKRSIEDRVQEEARCLVEELRK 158
>AY341248-1|AAP88931.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 9 protein.
Length = 490
Score = 35.9 bits (79), Expect = 0.37
Identities = 44/169 (26%), Positives = 75/169 (44%), Gaps = 9/169 (5%)
Frame = +3
Query: 237 NLFYVLLVPAVILWYTYWRMSRRRLYELAEKLNGPKGLPLIGNALEFVGGSAEIFSNIIQ 416
+L ++L + +L + WR S R + GP LP+IGN L+ G +I ++
Sbjct: 3 SLVVLVLCLSCLLLLSLWRQSSGR----GKLPPGPTPLPVIGNILQI--GIKDISKSLTN 56
Query: 417 KSLAFDNESVVKIWIGPRLLVFLYDPRDVEVILSSHVHIDKADEY--RFFKPWL-----G 575
S + V ++ G + +V L+ V+ L ID +E+ R P G
Sbjct: 57 LSKVYG--PVFTLYFGLKPIVVLHGYEAVKEAL-----IDLGEEFSGRGIFPLAERANRG 109
Query: 576 NGLLISTGQKWRSHRKLIAPTFHLNVL--KSFIDLFNANSRAVVEKLNK 716
G++ S G+KW+ R+ T + +S D +R +VE+L K
Sbjct: 110 FGIVFSNGKKWKEIRRFSLMTLRNFGMGKRSIEDRVQEEARCLVEELRK 158
>AL359672-1|CAH71303.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 9 protein.
Length = 490
Score = 35.9 bits (79), Expect = 0.37
Identities = 44/169 (26%), Positives = 75/169 (44%), Gaps = 9/169 (5%)
Frame = +3
Query: 237 NLFYVLLVPAVILWYTYWRMSRRRLYELAEKLNGPKGLPLIGNALEFVGGSAEIFSNIIQ 416
+L ++L + +L + WR S R + GP LP+IGN L+ G +I ++
Sbjct: 3 SLVVLVLCLSCLLLLSLWRQSSGR----GKLPPGPTPLPVIGNILQI--GIKDISKSLTN 56
Query: 417 KSLAFDNESVVKIWIGPRLLVFLYDPRDVEVILSSHVHIDKADEY--RFFKPWL-----G 575
S + V ++ G + +V L+ V+ L ID +E+ R P G
Sbjct: 57 LSKVYG--PVFTLYFGLKPIVVLHGYEAVKEAL-----IDLGEEFSGRGIFPLAERANRG 109
Query: 576 NGLLISTGQKWRSHRKLIAPTFHLNVL--KSFIDLFNANSRAVVEKLNK 716
G++ S G+KW+ R+ T + +S D +R +VE+L K
Sbjct: 110 FGIVFSNGKKWKEIRRFSLMTLRNFGMGKRSIEDRVQEEARCLVEELRK 158
>D00173-1|BAA00123.1| 487|Homo sapiens cytochrome P-450 protein.
Length = 487
Score = 35.5 bits (78), Expect = 0.49
Identities = 44/168 (26%), Positives = 74/168 (44%), Gaps = 9/168 (5%)
Frame = +3
Query: 240 LFYVLLVPAVILWYTYWRMSRRRLYELAEKLNGPKGLPLIGNALEFVGGSAEIFSNIIQK 419
L ++L + +L + WR S R + GP LP+IGN L+ G +I ++
Sbjct: 1 LVVLVLCLSCLLLLSLWRQSSGR----GKLPPGPTPLPVIGNILQI--GIKDISKSLTNL 54
Query: 420 SLAFDNESVVKIWIGPRLLVFLYDPRDVEVILSSHVHIDKADEY--RFFKPWL-----GN 578
S + V ++ G + +V L+ V+ L ID +E+ R P G
Sbjct: 55 SKVYG--PVFTLYFGLKPIVVLHGYEAVKEAL-----IDLGEEFSGRGIFPLAERANRGF 107
Query: 579 GLLISTGQKWRSHRKLIAPTFHLNVL--KSFIDLFNANSRAVVEKLNK 716
G++ S G+KW+ R+ T + +S D +R +VE+L K
Sbjct: 108 GIVFSNGKKWKEIRRFSLMTLRNFGMGKRSIEDRVQEEARCLVEELRK 155
>X13897-1|CAA32097.1| 489|Homo sapiens protein ( Human mRNA for
cytochrome P-450IIA. ).
Length = 489
Score = 35.1 bits (77), Expect = 0.64
Identities = 31/132 (23%), Positives = 64/132 (48%), Gaps = 2/132 (1%)
Frame = +3
Query: 336 GPKGLPLIGNALEFVGGSAEIFSNIIQKSLAFDNESVVKIWIGPRLLVFL--YDPRDVEV 509
GP LP IGN L+ + ++++++++ S + V I +GPR +V L +D +
Sbjct: 31 GPTPLPFIGNYLQL--NTEQMYNSLMKISERYG--PVFTIHLGPRRVVVLCGHDAVREAL 86
Query: 510 ILSSHVHIDKADEYRFFKPWLGNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANS 689
+ + + ++ F + G G++ S G++ + R+ F + L+ F
Sbjct: 87 VDQAEEFSGRGEQATFDWVFKGYGVVFSNGERAKQLRR-----FSIATLRD----FGVGK 137
Query: 690 RAVVEKLNKEAG 725
R + E++ +EAG
Sbjct: 138 RGIEERIQEEAG 149
>M33318-1|AAA52067.1| 494|Homo sapiens CYP2A protein.
Length = 494
Score = 35.1 bits (77), Expect = 0.64
Identities = 31/132 (23%), Positives = 64/132 (48%), Gaps = 2/132 (1%)
Frame = +3
Query: 336 GPKGLPLIGNALEFVGGSAEIFSNIIQKSLAFDNESVVKIWIGPRLLVFL--YDPRDVEV 509
GP LP IGN L+ + ++++++++ S + V I +GPR +V L +D +
Sbjct: 36 GPTPLPFIGNYLQL--NTEQMYNSLMKISERYG--PVFTIHLGPRRVVVLCGHDAVREAL 91
Query: 510 ILSSHVHIDKADEYRFFKPWLGNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANS 689
+ + + ++ F + G G++ S G++ + R+ F + L+ F
Sbjct: 92 VDQAEEFSGRGEQATFDWVFKGYGVVFSNGERAKQLRR-----FSIATLRD----FGVGK 142
Query: 690 RAVVEKLNKEAG 725
R + E++ +EAG
Sbjct: 143 RGIEERIQEEAG 154
>BC096256-1|AAH96256.1| 494|Homo sapiens cytochrome P450, family 2,
subfamily A, polypeptide 6 protein.
Length = 494
Score = 35.1 bits (77), Expect = 0.64
Identities = 31/132 (23%), Positives = 64/132 (48%), Gaps = 2/132 (1%)
Frame = +3
Query: 336 GPKGLPLIGNALEFVGGSAEIFSNIIQKSLAFDNESVVKIWIGPRLLVFL--YDPRDVEV 509
GP LP IGN L+ + ++++++++ S + V I +GPR +V L +D +
Sbjct: 36 GPTPLPFIGNYLQL--NTEQMYNSLMKISERYG--PVFTIHLGPRRVVVLCGHDAVREAL 91
Query: 510 ILSSHVHIDKADEYRFFKPWLGNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANS 689
+ + + ++ F + G G++ S G++ + R+ F + L+ F
Sbjct: 92 VDQAEEFSGRGEQATFDWVFKGYGVVFSNGERAKQLRR-----FSIATLRD----FGVGK 142
Query: 690 RAVVEKLNKEAG 725
R + E++ +EAG
Sbjct: 143 RGIEERIQEEAG 154
>BC096254-1|AAH96254.1| 494|Homo sapiens cytochrome P450, family 2,
subfamily A, polypeptide 6 protein.
Length = 494
Score = 35.1 bits (77), Expect = 0.64
Identities = 31/132 (23%), Positives = 64/132 (48%), Gaps = 2/132 (1%)
Frame = +3
Query: 336 GPKGLPLIGNALEFVGGSAEIFSNIIQKSLAFDNESVVKIWIGPRLLVFL--YDPRDVEV 509
GP LP IGN L+ + ++++++++ S + V I +GPR +V L +D +
Sbjct: 36 GPTPLPFIGNYLQL--NTEQMYNSLMKISERYG--PVFTIHLGPRRVVVLCGHDAVREAL 91
Query: 510 ILSSHVHIDKADEYRFFKPWLGNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANS 689
+ + + ++ F + G G++ S G++ + R+ F + L+ F
Sbjct: 92 VDQAEEFSGRGEQATFDWVFKGYGVVFSNGERAKQLRR-----FSIATLRD----FGVGK 142
Query: 690 RAVVEKLNKEAG 725
R + E++ +EAG
Sbjct: 143 RGIEERIQEEAG 154
>BC096253-1|AAH96253.3| 494|Homo sapiens cytochrome P450, family 2,
subfamily A, polypeptide 6 protein.
Length = 494
Score = 35.1 bits (77), Expect = 0.64
Identities = 31/132 (23%), Positives = 64/132 (48%), Gaps = 2/132 (1%)
Frame = +3
Query: 336 GPKGLPLIGNALEFVGGSAEIFSNIIQKSLAFDNESVVKIWIGPRLLVFL--YDPRDVEV 509
GP LP IGN L+ + ++++++++ S + V I +GPR +V L +D +
Sbjct: 36 GPTPLPFIGNYLQL--NTEQMYNSLMKISERYG--PVFTIHLGPRRVVVLCGHDAVREAL 91
Query: 510 ILSSHVHIDKADEYRFFKPWLGNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANS 689
+ + + ++ F + G G++ S G++ + R+ F + L+ F
Sbjct: 92 VDQAEEFSGRGEQATFDWVFKGYGVVFSNGERAKQLRR-----FSIATLRD----FGVGK 142
Query: 690 RAVVEKLNKEAG 725
R + E++ +EAG
Sbjct: 143 RGIEERIQEEAG 154
>AF182275-1|AAF13600.1| 494|Homo sapiens cytochrome P450-2A6
protein.
Length = 494
Score = 35.1 bits (77), Expect = 0.64
Identities = 31/132 (23%), Positives = 64/132 (48%), Gaps = 2/132 (1%)
Frame = +3
Query: 336 GPKGLPLIGNALEFVGGSAEIFSNIIQKSLAFDNESVVKIWIGPRLLVFL--YDPRDVEV 509
GP LP IGN L+ + ++++++++ S + V I +GPR +V L +D +
Sbjct: 36 GPTPLPFIGNYLQL--NTEQMYNSLMKISERYG--PVFTIHLGPRRVVVLCGHDAVREAL 91
Query: 510 ILSSHVHIDKADEYRFFKPWLGNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANS 689
+ + + ++ F + G G++ S G++ + R+ F + L+ F
Sbjct: 92 VDQAEEFSGRGEQATFDWVFKGYGVVFSNGERAKQLRR-----FSIATLRD----FGVGK 142
Query: 690 RAVVEKLNKEAG 725
R + E++ +EAG
Sbjct: 143 RGIEERIQEEAG 154
>M21939-1|AAA52158.1| 485|Homo sapiens CYP2C protein.
Length = 485
Score = 34.7 bits (76), Expect = 0.85
Identities = 43/165 (26%), Positives = 73/165 (44%), Gaps = 9/165 (5%)
Frame = +3
Query: 249 VLLVPAVILWYTYWRMSRRRLYELAEKLNGPKGLPLIGNALEFVGGSAEIFSNIIQKSLA 428
++L + +L + WR S R + GP LP+IGN L+ G +I ++ S
Sbjct: 2 LVLCLSCLLLLSLWRQSSGR----GKLPPGPTPLPVIGNILQI--GIKDISKSLTNLSKV 55
Query: 429 FDNESVVKIWIGPRLLVFLYDPRDVEVILSSHVHIDKADEY--RFFKPWL-----GNGLL 587
+ V ++ G + +V L+ V+ L ID +E+ R P G G++
Sbjct: 56 YG--PVFTLYFGLKPIVVLHGYEAVKEAL-----IDLGEEFSGRGIFPLAERANRGFGIV 108
Query: 588 ISTGQKWRSHRKLIAPTFHLNVL--KSFIDLFNANSRAVVEKLNK 716
S G+KW+ R+ T + +S D +R +VE+L K
Sbjct: 109 FSNGKKWKEIRRFSLMTLRNFGMGKRSIEDRVQEEARCLVEELRK 153
>M15331-1|AAA52157.1| 485|Homo sapiens CYP2C protein.
Length = 485
Score = 34.7 bits (76), Expect = 0.85
Identities = 43/165 (26%), Positives = 73/165 (44%), Gaps = 9/165 (5%)
Frame = +3
Query: 249 VLLVPAVILWYTYWRMSRRRLYELAEKLNGPKGLPLIGNALEFVGGSAEIFSNIIQKSLA 428
++L + +L + WR S R + GP LP+IGN L+ G +I ++ S
Sbjct: 2 LVLCLSCLLLLSLWRQSSGR----GKLPPGPTPLPVIGNILQI--GIKDISKSLTNLSKV 55
Query: 429 FDNESVVKIWIGPRLLVFLYDPRDVEVILSSHVHIDKADEY--RFFKPWL-----GNGLL 587
+ V ++ G + +V L+ V+ L ID +E+ R P G G++
Sbjct: 56 YG--PVFTLYFGLKPIVVLHGYEAVKEAL-----IDLGEEFSGRGIFPLAERANRGFGIV 108
Query: 588 ISTGQKWRSHRKLIAPTFHLNVL--KSFIDLFNANSRAVVEKLNK 716
S G+KW+ R+ T + +S D +R +VE+L K
Sbjct: 109 FSNGKKWKEIRRFSLMTLRNFGMGKRSIEDRVQEEARCLVEELRK 153
>M29874-1|AAA52144.1| 491|Homo sapiens CYP2B protein.
Length = 491
Score = 34.3 bits (75), Expect = 1.1
Identities = 37/166 (22%), Positives = 65/166 (39%), Gaps = 6/166 (3%)
Frame = +3
Query: 336 GPKGLPLIGNALEF-VGGSAEIFSNIIQKSLAFDNESVVKIWIGPRLLVFLYDPRDV-EV 509
GP+ LPL+GN L+ G + F +K V + +GPR +V L + E
Sbjct: 33 GPRPLPLLGNLLQMDRRGLLKSFLRFREK-----YGDVFTVHLGPRPVVMLCGVEAIREA 87
Query: 510 ILSSHVHIDKADEYRFFKPWL-GNGLLISTGQKWRSHRKLIAPTFHLNVL--KSFIDLFN 680
++ + P+ G G++ + G +W+ R+ T + +S +
Sbjct: 88 LVDKAEAFSGRGKIAMVDPFFRGYGVIFANGNRWKVLRRFSVTTMRDFGMGKRSVEERIQ 147
Query: 681 ANSRAVVEKLNKEAGT-FDCHDYMSECTVEILLETAMGVSKTTQDQ 815
++ ++E+L K G D T I+ G QDQ
Sbjct: 148 EEAQCLIEELRKSKGALMDPTFLFQSITANIICSIVFGKRFHYQDQ 193
>DQ298753-1|ABB84469.1| 491|Homo sapiens cytochrome P450, family 2,
subfamily B, polypeptide 6 protein.
Length = 491
Score = 34.3 bits (75), Expect = 1.1
Identities = 37/166 (22%), Positives = 65/166 (39%), Gaps = 6/166 (3%)
Frame = +3
Query: 336 GPKGLPLIGNALEF-VGGSAEIFSNIIQKSLAFDNESVVKIWIGPRLLVFLYDPRDV-EV 509
GP+ LPL+GN L+ G + F +K V + +GPR +V L + E
Sbjct: 33 GPRPLPLLGNLLQMDRRGLLKSFLRFREK-----YGDVFTVHLGPRPVVMLCGVEAIREA 87
Query: 510 ILSSHVHIDKADEYRFFKPWL-GNGLLISTGQKWRSHRKLIAPTFHLNVL--KSFIDLFN 680
++ + P+ G G++ + G +W+ R+ T + +S +
Sbjct: 88 LVDKAEAFSGRGKIAMVDPFFRGYGVIFANGNRWKVLRRFSVTTMRDFGMGKRSVEERIQ 147
Query: 681 ANSRAVVEKLNKEAGT-FDCHDYMSECTVEILLETAMGVSKTTQDQ 815
++ ++E+L K G D T I+ G QDQ
Sbjct: 148 EEAQCLIEELRKSKGALMDPTFLFQSITANIICSIVFGKRFHYQDQ 193
>BC067431-1|AAH67431.1| 491|Homo sapiens cytochrome P450, family 2,
subfamily B, polypeptide 6 protein.
Length = 491
Score = 34.3 bits (75), Expect = 1.1
Identities = 37/166 (22%), Positives = 65/166 (39%), Gaps = 6/166 (3%)
Frame = +3
Query: 336 GPKGLPLIGNALEF-VGGSAEIFSNIIQKSLAFDNESVVKIWIGPRLLVFLYDPRDV-EV 509
GP+ LPL+GN L+ G + F +K V + +GPR +V L + E
Sbjct: 33 GPRPLPLLGNLLQMDRRGLLKSFLRFREK-----YGDVFTVHLGPRPVVMLCGVEAIREA 87
Query: 510 ILSSHVHIDKADEYRFFKPWL-GNGLLISTGQKWRSHRKLIAPTFHLNVL--KSFIDLFN 680
++ + P+ G G++ + G +W+ R+ T + +S +
Sbjct: 88 LVDKAEAFSGRGKIAMVDPFFRGYGVIFANGNRWKVLRRFSVTTMRDFGMGKRSVEERIQ 147
Query: 681 ANSRAVVEKLNKEAGT-FDCHDYMSECTVEILLETAMGVSKTTQDQ 815
++ ++E+L K G D T I+ G QDQ
Sbjct: 148 EEAQCLIEELRKSKGALMDPTFLFQSITANIICSIVFGKRFHYQDQ 193
>AF182277-1|AAF13602.1| 491|Homo sapiens cytochrome P450-2B6
protein.
Length = 491
Score = 34.3 bits (75), Expect = 1.1
Identities = 37/166 (22%), Positives = 65/166 (39%), Gaps = 6/166 (3%)
Frame = +3
Query: 336 GPKGLPLIGNALEF-VGGSAEIFSNIIQKSLAFDNESVVKIWIGPRLLVFLYDPRDV-EV 509
GP+ LPL+GN L+ G + F +K V + +GPR +V L + E
Sbjct: 33 GPRPLPLLGNLLQMDRRGLLKSFLRFREK-----YGDVFTVHLGPRPVVMLCGVEAIREA 87
Query: 510 ILSSHVHIDKADEYRFFKPWL-GNGLLISTGQKWRSHRKLIAPTFHLNVL--KSFIDLFN 680
++ + P+ G G++ + G +W+ R+ T + +S +
Sbjct: 88 LVDKAEAFSGRGKIAMVDPFFRGYGVIFANGNRWKVLRRFSVTTMRDFGMGKRSVEERTQ 147
Query: 681 ANSRAVVEKLNKEAGT-FDCHDYMSECTVEILLETAMGVSKTTQDQ 815
++ ++E+L K G D T I+ G QDQ
Sbjct: 148 EEAQCLIEELRKSKGALMDATFLFHSITANIICSIVFGKRFHYQDQ 193
>AC023172-1|AAF32444.1| 491|Homo sapiens CYP2B6 protein.
Length = 491
Score = 34.3 bits (75), Expect = 1.1
Identities = 37/166 (22%), Positives = 65/166 (39%), Gaps = 6/166 (3%)
Frame = +3
Query: 336 GPKGLPLIGNALEF-VGGSAEIFSNIIQKSLAFDNESVVKIWIGPRLLVFLYDPRDV-EV 509
GP+ LPL+GN L+ G + F +K V + +GPR +V L + E
Sbjct: 33 GPRPLPLLGNLLQMDRRGLLKSFLRFREK-----YGDVFTVHLGPRPVVMLCGVEAIREA 87
Query: 510 ILSSHVHIDKADEYRFFKPWL-GNGLLISTGQKWRSHRKLIAPTFHLNVL--KSFIDLFN 680
++ + P+ G G++ + G +W+ R+ T + +S +
Sbjct: 88 LVDKAEAFSGRGKIAMVDPFFRGYGVIFANGNRWKVLRRFSVTTMRDFGMGKRSVEERIQ 147
Query: 681 ANSRAVVEKLNKEAGT-FDCHDYMSECTVEILLETAMGVSKTTQDQ 815
++ ++E+L K G D T I+ G QDQ
Sbjct: 148 EEAQCLIEELRKSKGALMDPTFLFQSITANIICSIVFGKRFHYQDQ 193
>M29873-1|AAA52143.1| 377|Homo sapiens CYP2B protein.
Length = 377
Score = 33.9 bits (74), Expect = 1.5
Identities = 38/166 (22%), Positives = 66/166 (39%), Gaps = 6/166 (3%)
Frame = +3
Query: 336 GPKGLPLIGNALEF-VGGSAEIFSNIIQKSLAFDNESVVKIWIGPRLLVFLYDPRDV-EV 509
GP+ LPL+GN L+ G + F +K V + +GPR +V L + E
Sbjct: 33 GPRPLPLLGNLLQMDRRGLLKSFLRFREK-----YGDVFTVHLGPRPVVMLCGVEAIREA 87
Query: 510 ILSSHVHIDKADEYRFFKP-WLGNGLLISTGQKWRSHRKLIAPTFHLNVL--KSFIDLFN 680
++ + + P + G G+L + G +W+ R+ T + +S +
Sbjct: 88 LVDNAEAFSGRGKIVIMDPVYQGYGMLFANGNRWKVLRRFSVTTMRDFGMGKRSVEERIQ 147
Query: 681 ANSRAVVEKLNKEAGTF-DCHDYMSECTVEILLETAMGVSKTTQDQ 815
++ ++E+L K G D T I+ G QDQ
Sbjct: 148 DEAQCLIEELRKSKGALVDPTFLFHSITANIICSIIFGKRFHYQDQ 193
>BC067430-1|AAH67430.1| 491|Homo sapiens cytochrome P450, family 2,
subfamily B, polypeptide 6 protein.
Length = 491
Score = 33.9 bits (74), Expect = 1.5
Identities = 37/166 (22%), Positives = 65/166 (39%), Gaps = 6/166 (3%)
Frame = +3
Query: 336 GPKGLPLIGNALEF-VGGSAEIFSNIIQKSLAFDNESVVKIWIGPRLLVFLYDPRDV-EV 509
GP+ LPL+GN L+ G + F +K V + +GPR +V L + E
Sbjct: 33 GPRPLPLLGNLLQMDRRGLLKSFLRFREK-----YGDVFTVHLGPRPVVMLCGVEAIREA 87
Query: 510 ILSSHVHIDKADEYRFFKPWL-GNGLLISTGQKWRSHRKLIAPTFHLNVL--KSFIDLFN 680
++ + P+ G G++ + G +W+ R+ T + +S +
Sbjct: 88 LVDKAEAFSGRGKIAMVDPFFRGYGVIFANGNRWKVLRRFSVTTMRDFGMGKRSVEERIQ 147
Query: 681 ANSRAVVEKLNKEAGT-FDCHDYMSECTVEILLETAMGVSKTTQDQ 815
++ ++E+L K G D T I+ G QDQ
Sbjct: 148 EEAQCLIEELRKSKGALMDPTFLFHSITANIICSIVFGKRFHYQDQ 193
>BC041174-1|AAH41174.1| 377|Homo sapiens CYP2B7P1 protein protein.
Length = 377
Score = 33.9 bits (74), Expect = 1.5
Identities = 38/166 (22%), Positives = 66/166 (39%), Gaps = 6/166 (3%)
Frame = +3
Query: 336 GPKGLPLIGNALEF-VGGSAEIFSNIIQKSLAFDNESVVKIWIGPRLLVFLYDPRDV-EV 509
GP+ LPL+GN L+ G + F +K V + +GPR +V L + E
Sbjct: 33 GPRPLPLLGNLLQMDRRGLLKSFLRFREK-----YGDVFTVHLGPRPVVMLCGVEAIREA 87
Query: 510 ILSSHVHIDKADEYRFFKP-WLGNGLLISTGQKWRSHRKLIAPTFHLNVL--KSFIDLFN 680
++ + + P + G G+L + G +W+ R+ T + +S +
Sbjct: 88 LVDNAEAFSGRGKIVIMDPVYQGYGMLFANGNRWKVLRRFSVTTMRDFGMGKRSVEERIQ 147
Query: 681 ANSRAVVEKLNKEAGTF-DCHDYMSECTVEILLETAMGVSKTTQDQ 815
++ ++E+L K G D T I+ G QDQ
Sbjct: 148 DEAQCLIEELRKSKGALVDPTFLFHSITANIICSIIFGKRFHYQDQ 193
>S46963-1|AAB23864.2| 477|Homo sapiens cytochrome P-450 protein.
Length = 477
Score = 33.5 bits (73), Expect = 2.0
Identities = 42/158 (26%), Positives = 69/158 (43%), Gaps = 9/158 (5%)
Frame = +3
Query: 270 ILWYTYWRMSRRRLYELAEKLNGPKGLPLIGNALEFVGGSAEIFSNIIQKSLAFDNESVV 449
+L + WR S R + GP LP+IGN L+ G +I ++ S + V
Sbjct: 1 MLLLSLWRQSSGR----GKLPPGPTPLPVIGNILQI--GIKDISKSLTNLSKVYG--PVF 52
Query: 450 KIWIGPRLLVFLYDPRDVEVILSSHVHIDKADEY--RFFKPWL-----GNGLLISTGQKW 608
++ G + +V L+ V+ L ID +E+ R P G G++ S G+KW
Sbjct: 53 TLYFGLKPIVVLHGYEAVKEAL-----IDLGEEFSGRGIFPLAERANRGFGIVFSNGKKW 107
Query: 609 RSHRKLIAPTFHLNVL--KSFIDLFNANSRAVVEKLNK 716
+ R+ T + +S D +R +VE+L K
Sbjct: 108 KEIRRFSLMTLRNFGMGKRSIEDRVQEEARCLVEELRK 145
>Y00498-1|CAA68550.1| 490|Homo sapiens IIC2 protein.
Length = 490
Score = 33.1 bits (72), Expect = 2.6
Identities = 38/160 (23%), Positives = 69/160 (43%), Gaps = 4/160 (2%)
Frame = +3
Query: 249 VLLVPAVILWYTYWRMSRRRLYELAEKLN-GPKGLPLIGNALEF-VGGSAEIFSNIIQKS 422
++L + +L ++ WR S RR KL GP LP+IGN L+ V + F+N S
Sbjct: 7 LVLCLSFMLLFSLWRQSCRR-----RKLPPGPTPLPIIGNMLQIDVKDICKSFTNF---S 58
Query: 423 LAFDNESVVKIWIGPRLLVFLYDPRDVEVILSSHVHIDKADEYRFFKPWLGNGLLISTGQ 602
+ V + P ++ Y+ +I + + + + G G++ S G+
Sbjct: 59 KVYGPVFTVYFGMNPIVVFHGYEAVKEALIDNGEEFSGRGNSPISQRITKGLGIISSNGK 118
Query: 603 KWRSHRKLIAPTFHLNVL--KSFIDLFNANSRAVVEKLNK 716
+W+ R+ T + +S D + +VE+L K
Sbjct: 119 RWKEIRRFSLTTLRNFGMGKRSIEDRVQEEAHCLVEELRK 158
>BC020596-1|AAH20596.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 8 protein.
Length = 490
Score = 33.1 bits (72), Expect = 2.6
Identities = 38/160 (23%), Positives = 69/160 (43%), Gaps = 4/160 (2%)
Frame = +3
Query: 249 VLLVPAVILWYTYWRMSRRRLYELAEKLN-GPKGLPLIGNALEF-VGGSAEIFSNIIQKS 422
++L + +L ++ WR S RR KL GP LP+IGN L+ V + F+N S
Sbjct: 7 LVLCLSFMLLFSLWRQSCRR-----RKLPPGPTPLPIIGNMLQIDVKDICKSFTNF---S 58
Query: 423 LAFDNESVVKIWIGPRLLVFLYDPRDVEVILSSHVHIDKADEYRFFKPWLGNGLLISTGQ 602
+ V + P ++ Y+ +I + + + + G G++ S G+
Sbjct: 59 KVYGPVFTVYFGMNPIVVFHGYESVKEALIDNGEEFSGRGNSPISQRITKGLGIISSNGK 118
Query: 603 KWRSHRKLIAPTFHLNVL--KSFIDLFNANSRAVVEKLNK 716
+W+ R+ T + +S D + +VE+L K
Sbjct: 119 RWKEIRRFSLTTLRNFGMGKRSIEDRVQEEAHCLVEELRK 158
>AY514490-1|AAR89907.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 8 protein.
Length = 490
Score = 33.1 bits (72), Expect = 2.6
Identities = 38/160 (23%), Positives = 69/160 (43%), Gaps = 4/160 (2%)
Frame = +3
Query: 249 VLLVPAVILWYTYWRMSRRRLYELAEKLN-GPKGLPLIGNALEF-VGGSAEIFSNIIQKS 422
++L + +L ++ WR S RR KL GP LP+IGN L+ V + F+N S
Sbjct: 7 LVLCLSFMLLFSLWRQSCRR-----RKLPPGPTPLPIIGNMLQIDVKDICKSFTNF---S 58
Query: 423 LAFDNESVVKIWIGPRLLVFLYDPRDVEVILSSHVHIDKADEYRFFKPWLGNGLLISTGQ 602
+ V + P ++ Y+ +I + + + + G G++ S G+
Sbjct: 59 KVYGPVFTVYFGMNPIVVFHGYEAVKEALIDNGEEFSGRGNSPISQRITKGLGIISSNGK 118
Query: 603 KWRSHRKLIAPTFHLNVL--KSFIDLFNANSRAVVEKLNK 716
+W+ R+ T + +S D + +VE+L K
Sbjct: 119 RWKEIRRFSLTTLRNFGMGKRSIEDRVQEEAHCLVEELRK 158
>AL359672-5|CAH71307.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 8 protein.
Length = 490
Score = 33.1 bits (72), Expect = 2.6
Identities = 38/160 (23%), Positives = 69/160 (43%), Gaps = 4/160 (2%)
Frame = +3
Query: 249 VLLVPAVILWYTYWRMSRRRLYELAEKLN-GPKGLPLIGNALEF-VGGSAEIFSNIIQKS 422
++L + +L ++ WR S RR KL GP LP+IGN L+ V + F+N S
Sbjct: 7 LVLCLSFMLLFSLWRQSCRR-----RKLPPGPTPLPIIGNMLQIDVKDICKSFTNF---S 58
Query: 423 LAFDNESVVKIWIGPRLLVFLYDPRDVEVILSSHVHIDKADEYRFFKPWLGNGLLISTGQ 602
+ V + P ++ Y+ +I + + + + G G++ S G+
Sbjct: 59 KVYGPVFTVYFGMNPIVVFHGYEAVKEALIDNGEEFSGRGNSPISQRITKGLGIISSNGK 118
Query: 603 KWRSHRKLIAPTFHLNVL--KSFIDLFNANSRAVVEKLNK 716
+W+ R+ T + +S D + +VE+L K
Sbjct: 119 RWKEIRRFSLTTLRNFGMGKRSIEDRVQEEAHCLVEELRK 158
>M21941-1|AAA52160.1| 480|Homo sapiens CYP2C protein.
Length = 480
Score = 32.3 bits (70), Expect = 4.5
Identities = 37/153 (24%), Positives = 65/153 (42%), Gaps = 4/153 (2%)
Frame = +3
Query: 270 ILWYTYWRMSRRRLYELAEKLN-GPKGLPLIGNALEF-VGGSAEIFSNIIQKSLAFDNES 443
+L ++ WR S RR KL GP LP+IGN L+ V + F+N S +
Sbjct: 4 MLLFSLWRQSCRR-----RKLPPGPTPLPIIGNMLQIDVKDICKSFTNF---SKVYGPVF 55
Query: 444 VVKIWIGPRLLVFLYDPRDVEVILSSHVHIDKADEYRFFKPWLGNGLLISTGQKWRSHRK 623
V + P ++ Y+ +I + + + + G G++ S G++W+ R+
Sbjct: 56 TVYFGMNPIVVFHGYEAVKEALIDNGEEFSGRGNSPISQRITKGLGIISSNGKRWKEIRR 115
Query: 624 LIAPTFHLNVL--KSFIDLFNANSRAVVEKLNK 716
T + +S D + +VE+L K
Sbjct: 116 FSLTTLRNFGMGKRSIEDRVQEEAHCLVEELRK 148
>M61856-1|AAB59356.1| 490|Homo sapiens cytochrome protein.
Length = 490
Score = 31.9 bits (69), Expect = 6.0
Identities = 37/160 (23%), Positives = 67/160 (41%), Gaps = 4/160 (2%)
Frame = +3
Query: 249 VLLVPAVILWYTYWRMSRRRLYELAEKLNGPKGLPLIGNALEFVGGSAEIFSNIIQKSLA 428
++L + + + WR S R +GP LP+IGN L+ ++ ++ S
Sbjct: 7 LVLCLSCLFLLSLWRQSSGR----GRLPSGPTPLPIIGNILQL--DVKDMSKSLTNFSKV 60
Query: 429 FDNESVVKIWIGPRLLVFLYDPRDVEVILSSH-VHIDKADEYRFF-KPWLGNGLLISTGQ 602
+ V ++ G + +V L+ V+ L H + K G G+L S G+
Sbjct: 61 YG--PVFTVYFGLKPIVVLHGYEAVKEALIDHGEEFSGRGSFPVAEKVNKGLGILFSNGK 118
Query: 603 KWRSHRKLIAPTFHLNVL--KSFIDLFNANSRAVVEKLNK 716
+W+ R+ T + +S D +R +VE+L K
Sbjct: 119 RWKEIRRFCLMTLRNFGMGKRSIEDRVQEEARCLVEELRK 158
>M17398-1|AAA35740.1| 393|Homo sapiens protein ( Human cytochrome
P-450 1 mRNA, complete cds, clone Hp1-2. ).
Length = 393
Score = 31.9 bits (69), Expect = 6.0
Identities = 38/160 (23%), Positives = 72/160 (45%), Gaps = 2/160 (1%)
Frame = +3
Query: 249 VLLVPAVILWYTYWRMSRRRLYELAEKLN-GPKGLPLIGNALEF-VGGSAEIFSNIIQKS 422
++L + +L ++ WR S RR KL GP LP+IGN L+ V + F+N S
Sbjct: 7 LVLCLSFMLLFSLWRQSCRR-----RKLPPGPTPLPIIGNMLQIDVKDICKSFTNF---S 58
Query: 423 LAFDNESVVKIWIGPRLLVFLYDPRDVEVILSSHVHIDKADEYRFFKPWLGNGLLISTGQ 602
+ V + P ++ Y+ +I + + + + G G++ S G+
Sbjct: 59 KVYGPVFTVYFGMNPIVVFHGYEAVKEALIDNGEEFSGRGNSPISQRITKGLGIISSNGK 118
Query: 603 KWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVEKLNKEA 722
+W+ R+ F L L++ F R++ +++ +EA
Sbjct: 119 RWKEIRR-----FSLTNLRN----FGMGKRSIEDRVQEEA 149
>M17397-1|AAA35739.1| 490|Homo sapiens protein ( Human cytochrome
P-450 1 functional form mRNA, complete cds. ).
Length = 490
Score = 31.9 bits (69), Expect = 6.0
Identities = 38/160 (23%), Positives = 72/160 (45%), Gaps = 2/160 (1%)
Frame = +3
Query: 249 VLLVPAVILWYTYWRMSRRRLYELAEKLN-GPKGLPLIGNALEF-VGGSAEIFSNIIQKS 422
++L + +L ++ WR S RR KL GP LP+IGN L+ V + F+N S
Sbjct: 7 LVLCLSFMLLFSLWRQSCRR-----RKLPPGPTPLPIIGNMLQIDVKDICKSFTNF---S 58
Query: 423 LAFDNESVVKIWIGPRLLVFLYDPRDVEVILSSHVHIDKADEYRFFKPWLGNGLLISTGQ 602
+ V + P ++ Y+ +I + + + + G G++ S G+
Sbjct: 59 KVYGPVFTVYFGMNPIVVFHGYEAVKEALIDNGEEFSGRGNSPISQRITKGLGIISSNGK 118
Query: 603 KWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVEKLNKEA 722
+W+ R+ F L L++ F R++ +++ +EA
Sbjct: 119 RWKEIRR-----FSLTNLRN----FGMGKRSIEDRVQEEA 149
>L16876-1|AAA02630.1| 490|Homo sapiens cytochrome P-4502C18
protein.
Length = 490
Score = 31.9 bits (69), Expect = 6.0
Identities = 37/160 (23%), Positives = 67/160 (41%), Gaps = 4/160 (2%)
Frame = +3
Query: 249 VLLVPAVILWYTYWRMSRRRLYELAEKLNGPKGLPLIGNALEFVGGSAEIFSNIIQKSLA 428
++L + + + WR S R +GP LP+IGN L+ ++ ++ S
Sbjct: 7 LVLCLSCLFLLSLWRQSSGR----GRLPSGPTPLPIIGNILQL--DVKDMSKSLTNFSKV 60
Query: 429 FDNESVVKIWIGPRLLVFLYDPRDVEVILSSH-VHIDKADEYRFF-KPWLGNGLLISTGQ 602
+ V ++ G + +V L+ V+ L H + K G G+L S G+
Sbjct: 61 YG--PVFTVYFGLKPIVVLHGYEAVKEALIDHGEEFSGRGSFPVAEKVNKGLGILFSNGK 118
Query: 603 KWRSHRKLIAPTFHLNVL--KSFIDLFNANSRAVVEKLNK 716
+W+ R+ T + +S D +R +VE+L K
Sbjct: 119 RWKEIRRFCLMTLRNFGMGKRSIEDRVQEEARCLVEELRK 158
>BC096260-1|AAH96260.1| 431|Homo sapiens CYP2C18 protein protein.
Length = 431
Score = 31.9 bits (69), Expect = 6.0
Identities = 37/160 (23%), Positives = 67/160 (41%), Gaps = 4/160 (2%)
Frame = +3
Query: 249 VLLVPAVILWYTYWRMSRRRLYELAEKLNGPKGLPLIGNALEFVGGSAEIFSNIIQKSLA 428
++L + + + WR S R +GP LP+IGN L+ ++ ++ S
Sbjct: 7 LVLCLSCLFLLSLWRQSSGR----GRLPSGPTPLPIIGNILQL--DVKDMSKSLTNFSKV 60
Query: 429 FDNESVVKIWIGPRLLVFLYDPRDVEVILSSH-VHIDKADEYRFF-KPWLGNGLLISTGQ 602
+ V ++ G + +V L+ V+ L H + K G G+L S G+
Sbjct: 61 YG--PVFTVYFGLKPIVVLHGYEAVKEALIDHGEEFSGRGSFPVAEKVNKGLGILFSNGK 118
Query: 603 KWRSHRKLIAPTFHLNVL--KSFIDLFNANSRAVVEKLNK 716
+W+ R+ T + +S D +R +VE+L K
Sbjct: 119 RWKEIRRFCLMTLRNFGMGKRSIEDRVQEEARCLVEELRK 158
>BC096259-1|AAH96259.1| 443|Homo sapiens CYP2C18 protein protein.
Length = 443
Score = 31.9 bits (69), Expect = 6.0
Identities = 37/160 (23%), Positives = 67/160 (41%), Gaps = 4/160 (2%)
Frame = +3
Query: 249 VLLVPAVILWYTYWRMSRRRLYELAEKLNGPKGLPLIGNALEFVGGSAEIFSNIIQKSLA 428
++L + + + WR S R +GP LP+IGN L+ ++ ++ S
Sbjct: 7 LVLCLSCLFLLSLWRQSSGR----GRLPSGPTPLPIIGNILQL--DVKDMSKSLTNFSKV 60
Query: 429 FDNESVVKIWIGPRLLVFLYDPRDVEVILSSH-VHIDKADEYRFF-KPWLGNGLLISTGQ 602
+ V ++ G + +V L+ V+ L H + K G G+L S G+
Sbjct: 61 YG--PVFTVYFGLKPIVVLHGYEAVKEALIDHGEEFSGRGSFPVAEKVNKGLGILFSNGK 118
Query: 603 KWRSHRKLIAPTFHLNVL--KSFIDLFNANSRAVVEKLNK 716
+W+ R+ T + +S D +R +VE+L K
Sbjct: 119 RWKEIRRFCLMTLRNFGMGKRSIEDRVQEEARCLVEELRK 158
>BC096258-1|AAH96258.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 18 protein.
Length = 490
Score = 31.9 bits (69), Expect = 6.0
Identities = 37/160 (23%), Positives = 67/160 (41%), Gaps = 4/160 (2%)
Frame = +3
Query: 249 VLLVPAVILWYTYWRMSRRRLYELAEKLNGPKGLPLIGNALEFVGGSAEIFSNIIQKSLA 428
++L + + + WR S R +GP LP+IGN L+ ++ ++ S
Sbjct: 7 LVLCLSCLFLLSLWRQSSGR----GRLPSGPTPLPIIGNILQL--DVKDMSKSLTNFSKV 60
Query: 429 FDNESVVKIWIGPRLLVFLYDPRDVEVILSSH-VHIDKADEYRFF-KPWLGNGLLISTGQ 602
+ V ++ G + +V L+ V+ L H + K G G+L S G+
Sbjct: 61 YG--PVFTVYFGLKPIVVLHGYEAVKEALIDHGEEFSGRGSFPVAEKVNKGLGILFSNGK 118
Query: 603 KWRSHRKLIAPTFHLNVL--KSFIDLFNANSRAVVEKLNK 716
+W+ R+ T + +S D +R +VE+L K
Sbjct: 119 RWKEIRRFCLMTLRNFGMGKRSIEDRVQEEARCLVEELRK 158
>BC096257-1|AAH96257.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 18 protein.
Length = 490
Score = 31.9 bits (69), Expect = 6.0
Identities = 37/160 (23%), Positives = 67/160 (41%), Gaps = 4/160 (2%)
Frame = +3
Query: 249 VLLVPAVILWYTYWRMSRRRLYELAEKLNGPKGLPLIGNALEFVGGSAEIFSNIIQKSLA 428
++L + + + WR S R +GP LP+IGN L+ ++ ++ S
Sbjct: 7 LVLCLSCLFLLSLWRQSSGR----GRLPSGPTPLPIIGNILQL--DVKDMSKSLTNFSKV 60
Query: 429 FDNESVVKIWIGPRLLVFLYDPRDVEVILSSH-VHIDKADEYRFF-KPWLGNGLLISTGQ 602
+ V ++ G + +V L+ V+ L H + K G G+L S G+
Sbjct: 61 YG--PVFTVYFGLKPIVVLHGYEAVKEALIDHGEEFSGRGSFPVAEKVNKGLGILFSNGK 118
Query: 603 KWRSHRKLIAPTFHLNVL--KSFIDLFNANSRAVVEKLNK 716
+W+ R+ T + +S D +R +VE+L K
Sbjct: 119 RWKEIRRFCLMTLRNFGMGKRSIEDRVQEEARCLVEELRK 158
>BC069666-1|AAH69666.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 18 protein.
Length = 490
Score = 31.9 bits (69), Expect = 6.0
Identities = 37/160 (23%), Positives = 67/160 (41%), Gaps = 4/160 (2%)
Frame = +3
Query: 249 VLLVPAVILWYTYWRMSRRRLYELAEKLNGPKGLPLIGNALEFVGGSAEIFSNIIQKSLA 428
++L + + + WR S R +GP LP+IGN L+ ++ ++ S
Sbjct: 7 LVLCLSCLFLLSLWRQSSGR----GRLPSGPTPLPIIGNILQL--DVKDMSKSLTNFSKV 60
Query: 429 FDNESVVKIWIGPRLLVFLYDPRDVEVILSSH-VHIDKADEYRFF-KPWLGNGLLISTGQ 602
+ V ++ G + +V L+ V+ L H + K G G+L S G+
Sbjct: 61 YG--PVFTVYFGLKPIVVLHGYEAVKEALIDHGEEFSGRGSFPVAEKVNKGLGILFSNGK 118
Query: 603 KWRSHRKLIAPTFHLNVL--KSFIDLFNANSRAVVEKLNK 716
+W+ R+ T + +S D +R +VE+L K
Sbjct: 119 RWKEIRRFCLMTLRNFGMGKRSIEDRVQEEARCLVEELRK 158
>AL583836-1|CAH74067.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 18 protein.
Length = 490
Score = 31.9 bits (69), Expect = 6.0
Identities = 37/160 (23%), Positives = 67/160 (41%), Gaps = 4/160 (2%)
Frame = +3
Query: 249 VLLVPAVILWYTYWRMSRRRLYELAEKLNGPKGLPLIGNALEFVGGSAEIFSNIIQKSLA 428
++L + + + WR S R +GP LP+IGN L+ ++ ++ S
Sbjct: 7 LVLCLSCLFLLSLWRQSSGR----GRLPSGPTPLPIIGNILQL--DVKDMSKSLTNFSKV 60
Query: 429 FDNESVVKIWIGPRLLVFLYDPRDVEVILSSH-VHIDKADEYRFF-KPWLGNGLLISTGQ 602
+ V ++ G + +V L+ V+ L H + K G G+L S G+
Sbjct: 61 YG--PVFTVYFGLKPIVVLHGYEAVKEALIDHGEEFSGRGSFPVAEKVNKGLGILFSNGK 118
Query: 603 KWRSHRKLIAPTFHLNVL--KSFIDLFNANSRAVVEKLNK 716
+W+ R+ T + +S D +R +VE+L K
Sbjct: 119 RWKEIRRFCLMTLRNFGMGKRSIEDRVQEEARCLVEELRK 158
>AK223510-1|BAD97230.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 18 variant protein.
Length = 490
Score = 31.9 bits (69), Expect = 6.0
Identities = 32/132 (24%), Positives = 57/132 (43%), Gaps = 4/132 (3%)
Frame = +3
Query: 333 NGPKGLPLIGNALEFVGGSAEIFSNIIQKSLAFDNESVVKIWIGPRLLVFLYDPRDVEVI 512
+GP LP+IGN L+ ++ ++ S + V ++ G + +V L+ V+
Sbjct: 31 SGPTPLPIIGNILQL--DVKDMSKSLTNFSKVYG--PVFTVYFGLKPIVVLHGYEAVKEA 86
Query: 513 LSSHVH--IDKADEYRFFKPWLGNGLLISTGQKWRSHRKLIAPTFHLNVL--KSFIDLFN 680
L H + K G G+L S G++W+ R+ T + +S D
Sbjct: 87 LIDHGEEFFGRGSFPVAEKVNKGLGILFSNGKRWKEIRRFCLMTLRNFGMGKRSIEDRVQ 146
Query: 681 ANSRAVVEKLNK 716
+R +VE+L K
Sbjct: 147 EEARCLVEELRK 158
>BX928748-1|CAH74051.1| 5635|Homo sapiens protein ( Human DNA sequence
from clone RP11-465I11 on chromosome 1 Contains part of
the gene for hemicentin (FIBL-6). ).
Length = 5635
Score = 31.5 bits (68), Expect = 7.9
Identities = 13/35 (37%), Positives = 24/35 (68%), Gaps = 1/35 (2%)
Frame = +3
Query: 636 TFHLNVLKSFIDLFNANSRAVVEKLNKE-AGTFDC 737
TF+ N++ + D N +S V+E+++KE +GT+ C
Sbjct: 4294 TFNNNIIPAHFDSVNGHSELVIERVSKEDSGTYVC 4328
>BC104909-1|AAI04910.1| 501|Homo sapiens cytochrome P450, family 2,
subfamily R, polypeptide 1 protein.
Length = 501
Score = 31.5 bits (68), Expect = 7.9
Identities = 31/105 (29%), Positives = 47/105 (44%), Gaps = 3/105 (2%)
Frame = +3
Query: 336 GPKGLPLIGNALEFVGGSAEIFSNIIQKSLAFDNESVVKIWIGPRLLVFL--YDPRDVEV 509
GP GLP IGN + + S+E+ ++K E + + +G V L YD +
Sbjct: 42 GPPGLPFIGN-IYSLAASSELPHVYMRKQSQVYGE-IFSLDLGGISTVVLNGYDVVKECL 99
Query: 510 ILSSHVHIDKADEYRFFKPWLGNGLLIST-GQKWRSHRKLIAPTF 641
+ S + D+ F K GLL S G+ W HR+L +F
Sbjct: 100 VHQSEIFADRPCLPLFMKMTKMGGLLNSRYGRGWVDHRRLAVNSF 144
>BC104907-1|AAI04908.1| 501|Homo sapiens cytochrome P450, family 2,
subfamily R, polypeptide 1 protein.
Length = 501
Score = 31.5 bits (68), Expect = 7.9
Identities = 31/105 (29%), Positives = 47/105 (44%), Gaps = 3/105 (2%)
Frame = +3
Query: 336 GPKGLPLIGNALEFVGGSAEIFSNIIQKSLAFDNESVVKIWIGPRLLVFL--YDPRDVEV 509
GP GLP IGN + + S+E+ ++K E + + +G V L YD +
Sbjct: 42 GPPGLPFIGN-IYSLAASSELPHVYMRKQSQVYGE-IFSLDLGGISTVVLNGYDVVKECL 99
Query: 510 ILSSHVHIDKADEYRFFKPWLGNGLLIST-GQKWRSHRKLIAPTF 641
+ S + D+ F K GLL S G+ W HR+L +F
Sbjct: 100 VHQSEIFADRPCLPLFMKMTKMGGLLNSRYGRGWVDHRRLAVNSF 144
>AY323817-1|AAQ23114.1| 501|Homo sapiens cytochrome P450 2R1
protein.
Length = 501
Score = 31.5 bits (68), Expect = 7.9
Identities = 31/105 (29%), Positives = 47/105 (44%), Gaps = 3/105 (2%)
Frame = +3
Query: 336 GPKGLPLIGNALEFVGGSAEIFSNIIQKSLAFDNESVVKIWIGPRLLVFL--YDPRDVEV 509
GP GLP IGN + + S+E+ ++K E + + +G V L YD +
Sbjct: 42 GPPGLPFIGN-IYSLAASSELPHVYMRKQSQVYGE-IFSLDLGGISTVVLNGYDVVKECL 99
Query: 510 ILSSHVHIDKADEYRFFKPWLGNGLLIST-GQKWRSHRKLIAPTF 641
+ S + D+ F K GLL S G+ W HR+L +F
Sbjct: 100 VHQSEIFADRPCLPLFMKMTKMGGLLNSRYGRGWVDHRRLAVNSF 144
>AL391824-1|CAI17865.1| 5635|Homo sapiens protein ( Human DNA sequence
from clone GS1-268N14 on chromosome 1 Contains part of
the gene for hemicentin. ).
Length = 5635
Score = 31.5 bits (68), Expect = 7.9
Identities = 13/35 (37%), Positives = 24/35 (68%), Gaps = 1/35 (2%)
Frame = +3
Query: 636 TFHLNVLKSFIDLFNANSRAVVEKLNKE-AGTFDC 737
TF+ N++ + D N +S V+E+++KE +GT+ C
Sbjct: 4294 TFNNNIIPAHFDSVNGHSELVIERVSKEDSGTYVC 4328
>AL135797-1|CAI17871.1| 5635|Homo sapiens protein ( Human DNA sequence
from clone GS1-77J13 on chromosome 1 Contains part of
the gene for hemicentin. ).
Length = 5635
Score = 31.5 bits (68), Expect = 7.9
Identities = 13/35 (37%), Positives = 24/35 (68%), Gaps = 1/35 (2%)
Frame = +3
Query: 636 TFHLNVLKSFIDLFNANSRAVVEKLNKE-AGTFDC 737
TF+ N++ + D N +S V+E+++KE +GT+ C
Sbjct: 4294 TFNNNIIPAHFDSVNGHSELVIERVSKEDSGTYVC 4328
>AL135796-1|CAI17854.1| 5635|Homo sapiens protein ( Human DNA sequence
from clone GS1-164L12 on chromosome 1 Contains part of
the gene for hemicentin. ).
Length = 5635
Score = 31.5 bits (68), Expect = 7.9
Identities = 13/35 (37%), Positives = 24/35 (68%), Gaps = 1/35 (2%)
Frame = +3
Query: 636 TFHLNVLKSFIDLFNANSRAVVEKLNKE-AGTFDC 737
TF+ N++ + D N +S V+E+++KE +GT+ C
Sbjct: 4294 TFNNNIIPAHFDSVNGHSELVIERVSKEDSGTYVC 4328
>AL133553-2|CAI17858.1| 5635|Homo sapiens protein ( Human DNA sequence
from clone GS1-174L6 on chromosome 1 Contains the3' end
of the gene for hemicentin, the PRG4 gene for
proteoglycan 4 ).
Length = 5635
Score = 31.5 bits (68), Expect = 7.9
Identities = 13/35 (37%), Positives = 24/35 (68%), Gaps = 1/35 (2%)
Frame = +3
Query: 636 TFHLNVLKSFIDLFNANSRAVVEKLNKE-AGTFDC 737
TF+ N++ + D N +S V+E+++KE +GT+ C
Sbjct: 4294 TFNNNIIPAHFDSVNGHSELVIERVSKEDSGTYVC 4328
>AL133515-1|CAI17853.1| 5635|Homo sapiens protein ( Human DNA sequence
from clone GS1-153O3 on chromosome 1 Contains part of
the gene for hemicentin. ).
Length = 5635
Score = 31.5 bits (68), Expect = 7.9
Identities = 13/35 (37%), Positives = 24/35 (68%), Gaps = 1/35 (2%)
Frame = +3
Query: 636 TFHLNVLKSFIDLFNANSRAVVEKLNKE-AGTFDC 737
TF+ N++ + D N +S V+E+++KE +GT+ C
Sbjct: 4294 TFNNNIIPAHFDSVNGHSELVIERVSKEDSGTYVC 4328
>AL121996-1|CAI17844.1| 5635|Homo sapiens protein ( Human DNA sequence
from clone GS1-118G19 on chromosome 1q25.1-31.1 Contains
the 5' end of the gene for hemicentin. ).
Length = 5635
Score = 31.5 bits (68), Expect = 7.9
Identities = 13/35 (37%), Positives = 24/35 (68%), Gaps = 1/35 (2%)
Frame = +3
Query: 636 TFHLNVLKSFIDLFNANSRAVVEKLNKE-AGTFDC 737
TF+ N++ + D N +S V+E+++KE +GT+ C
Sbjct: 4294 TFNNNIIPAHFDSVNGHSELVIERVSKEDSGTYVC 4328
>AL118512-1|CAI17864.1| 5635|Homo sapiens protein ( Human DNA sequence
from clone GS1-248A21 on chromosome 1q31.1-31.3 Contains
part of the gene for hemicentin (FIBL-6). ).
Length = 5635
Score = 31.5 bits (68), Expect = 7.9
Identities = 13/35 (37%), Positives = 24/35 (68%), Gaps = 1/35 (2%)
Frame = +3
Query: 636 TFHLNVLKSFIDLFNANSRAVVEKLNKE-AGTFDC 737
TF+ N++ + D N +S V+E+++KE +GT+ C
Sbjct: 4294 TFNNNIIPAHFDSVNGHSELVIERVSKEDSGTYVC 4328
>AJ306906-1|CAC37630.1| 2673|Homo sapiens fibulin-6 protein.
Length = 2673
Score = 31.5 bits (68), Expect = 7.9
Identities = 13/35 (37%), Positives = 24/35 (68%), Gaps = 1/35 (2%)
Frame = +3
Query: 636 TFHLNVLKSFIDLFNANSRAVVEKLNKE-AGTFDC 737
TF+ N++ + D N +S V+E+++KE +GT+ C
Sbjct: 1332 TFNNNIIPAHFDSVNGHSELVIERVSKEDSGTYVC 1366
>AF156100-1|AAK68690.1| 5636|Homo sapiens hemicentin protein.
Length = 5636
Score = 31.5 bits (68), Expect = 7.9
Identities = 13/35 (37%), Positives = 24/35 (68%), Gaps = 1/35 (2%)
Frame = +3
Query: 636 TFHLNVLKSFIDLFNANSRAVVEKLNKE-AGTFDC 737
TF+ N++ + D N +S V+E+++KE +GT+ C
Sbjct: 4295 TFNNNIIPAHFDSVNGHSELVIERVSKEDSGTYVC 4329
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 175,693,401
Number of Sequences: 237096
Number of extensions: 3444027
Number of successful extensions: 6093
Number of sequences better than 10.0: 186
Number of HSP's better than 10.0 without gapping: 5816
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 6037
length of database: 76,859,062
effective HSP length: 93
effective length of database: 54,809,134
effective search space used: 21265943992
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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