Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= 030623sawa_C06_e43_06.seq
(1565 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
S62076-1|AAD13932.1| 529|Homo sapiens HEXA protein. 103 2e-21
M16424-1|AAB00965.1| 529|Homo sapiens HEXA protein. 103 2e-21
M13520-1|AAA51827.1| 490|Homo sapiens HEXA protein. 103 2e-21
BC084537-1|AAH84537.1| 529|Homo sapiens hexosaminidase A (alpha... 103 2e-21
BC021030-1|AAH21030.1| 309|Homo sapiens HEXA protein protein. 103 2e-21
BC018927-1|AAH18927.1| 529|Homo sapiens hexosaminidase A (alpha... 103 2e-21
BC001138-1|AAH01138.2| 409|Homo sapiens HEXA protein protein. 103 2e-21
AK222502-1|BAD96222.1| 529|Homo sapiens hexosaminidase A prepro... 103 2e-21
M23294-1|AAA52645.1| 556|Homo sapiens beta-hexosaminidase beta-... 102 4e-21
M19735-1|AAA68620.1| 544|Homo sapiens beta-hexosaminidase beta-... 102 4e-21
M13519-1|AAA51828.1| 572|Homo sapiens HEXB protein. 102 4e-21
BT009919-1|AAP88921.1| 556|Homo sapiens hexosaminidase B (beta ... 102 4e-21
BC017378-1|AAH17378.1| 556|Homo sapiens hexosaminidase B (beta ... 102 4e-21
AY643499-1|AAV48875.1| 331|Homo sapiens ENC-1AS protein. 102 4e-21
AF378118-1|AAM46114.1| 556|Homo sapiens cervical cancer proto-o... 102 4e-21
>S62076-1|AAD13932.1| 529|Homo sapiens HEXA protein.
Length = 529
Score = 103 bits (246), Expect = 2e-21
Identities = 57/145 (39%), Positives = 84/145 (57%), Gaps = 5/145 (3%)
Frame = +3
Query: 96 IQVWK---PHEKYEMLHILSK-GHKVVYSSAWYLDHLMSGGDWTNFYLSDPRQMVRQYSP 263
IQVW+ P + L +++K G + + S+ WYL+ + G DW +FY+ +P + + +P
Sbjct: 389 IQVWREDIPVNYMKELELVTKAGFRALLSAPWYLNRISYGPDWKDFYVVEP--LAFEGTP 446
Query: 264 TANVDNIVGGEACMWGEVVNDMNVISRIWSRASAVAERLWSPE-TEGLRYMNKVPNEVYS 440
++GGEACMWGE V++ N++ R+W RA AVAERLWS + T L + Y
Sbjct: 447 EQKA-LVIGGEACMWGEYVDNTNLVPRLWPRAGAVAERLWSNKLTSDLTF-------AYE 498
Query: 441 RLEEHTCRMNRRGIDAQPPSGPGFC 515
RL C + RRG+ AQ P GFC
Sbjct: 499 RLSHFRCELLRRGVQAQ-PLNVGFC 522
>M16424-1|AAB00965.1| 529|Homo sapiens HEXA protein.
Length = 529
Score = 103 bits (246), Expect = 2e-21
Identities = 57/145 (39%), Positives = 84/145 (57%), Gaps = 5/145 (3%)
Frame = +3
Query: 96 IQVWK---PHEKYEMLHILSK-GHKVVYSSAWYLDHLMSGGDWTNFYLSDPRQMVRQYSP 263
IQVW+ P + L +++K G + + S+ WYL+ + G DW +FY+ +P + + +P
Sbjct: 389 IQVWREDIPVNYMKELELVTKAGFRALLSAPWYLNRISYGPDWKDFYVVEP--LAFEGTP 446
Query: 264 TANVDNIVGGEACMWGEVVNDMNVISRIWSRASAVAERLWSPE-TEGLRYMNKVPNEVYS 440
++GGEACMWGE V++ N++ R+W RA AVAERLWS + T L + Y
Sbjct: 447 EQKA-LVIGGEACMWGEYVDNTNLVPRLWPRAGAVAERLWSNKLTSDLTF-------AYE 498
Query: 441 RLEEHTCRMNRRGIDAQPPSGPGFC 515
RL C + RRG+ AQ P GFC
Sbjct: 499 RLSHFRCELLRRGVQAQ-PLNVGFC 522
>M13520-1|AAA51827.1| 490|Homo sapiens HEXA protein.
Length = 490
Score = 103 bits (246), Expect = 2e-21
Identities = 57/145 (39%), Positives = 84/145 (57%), Gaps = 5/145 (3%)
Frame = +3
Query: 96 IQVWK---PHEKYEMLHILSK-GHKVVYSSAWYLDHLMSGGDWTNFYLSDPRQMVRQYSP 263
IQVW+ P + L +++K G + + S+ WYL+ + G DW +FY+ +P + + +P
Sbjct: 350 IQVWREDIPVNYMKELELVTKAGFRALLSAPWYLNRISYGPDWKDFYVVEP--LAFEGTP 407
Query: 264 TANVDNIVGGEACMWGEVVNDMNVISRIWSRASAVAERLWSPE-TEGLRYMNKVPNEVYS 440
++GGEACMWGE V++ N++ R+W RA AVAERLWS + T L + Y
Sbjct: 408 EQKA-LVIGGEACMWGEYVDNTNLVPRLWPRAGAVAERLWSNKLTSDLTF-------AYE 459
Query: 441 RLEEHTCRMNRRGIDAQPPSGPGFC 515
RL C + RRG+ AQ P GFC
Sbjct: 460 RLSHFRCELLRRGVQAQ-PLNVGFC 483
>BC084537-1|AAH84537.1| 529|Homo sapiens hexosaminidase A (alpha
polypeptide) protein.
Length = 529
Score = 103 bits (246), Expect = 2e-21
Identities = 57/145 (39%), Positives = 84/145 (57%), Gaps = 5/145 (3%)
Frame = +3
Query: 96 IQVWK---PHEKYEMLHILSK-GHKVVYSSAWYLDHLMSGGDWTNFYLSDPRQMVRQYSP 263
IQVW+ P + L +++K G + + S+ WYL+ + G DW +FY+ +P + + +P
Sbjct: 389 IQVWREDIPVNYMKELELVTKAGFRALLSAPWYLNRISYGPDWKDFYVVEP--LAFEGTP 446
Query: 264 TANVDNIVGGEACMWGEVVNDMNVISRIWSRASAVAERLWSPE-TEGLRYMNKVPNEVYS 440
++GGEACMWGE V++ N++ R+W RA AVAERLWS + T L + Y
Sbjct: 447 EQKA-LVIGGEACMWGEYVDNTNLVPRLWPRAGAVAERLWSNKLTSDLTF-------AYE 498
Query: 441 RLEEHTCRMNRRGIDAQPPSGPGFC 515
RL C + RRG+ AQ P GFC
Sbjct: 499 RLSHFRCELLRRGVQAQ-PLNVGFC 522
>BC021030-1|AAH21030.1| 309|Homo sapiens HEXA protein protein.
Length = 309
Score = 103 bits (246), Expect = 2e-21
Identities = 57/145 (39%), Positives = 84/145 (57%), Gaps = 5/145 (3%)
Frame = +3
Query: 96 IQVWK---PHEKYEMLHILSK-GHKVVYSSAWYLDHLMSGGDWTNFYLSDPRQMVRQYSP 263
IQVW+ P + L +++K G + + S+ WYL+ + G DW +FY+ +P + + +P
Sbjct: 169 IQVWREDIPVNYMKELELVTKAGFRALLSAPWYLNRISYGPDWKDFYVVEP--LAFEGTP 226
Query: 264 TANVDNIVGGEACMWGEVVNDMNVISRIWSRASAVAERLWSPE-TEGLRYMNKVPNEVYS 440
++GGEACMWGE V++ N++ R+W RA AVAERLWS + T L + Y
Sbjct: 227 EQKA-LVIGGEACMWGEYVDNTNLVPRLWPRAGAVAERLWSNKLTSDLTF-------AYE 278
Query: 441 RLEEHTCRMNRRGIDAQPPSGPGFC 515
RL C + RRG+ AQ P GFC
Sbjct: 279 RLSHFRCELLRRGVQAQ-PLNVGFC 302
>BC018927-1|AAH18927.1| 529|Homo sapiens hexosaminidase A (alpha
polypeptide) protein.
Length = 529
Score = 103 bits (246), Expect = 2e-21
Identities = 57/145 (39%), Positives = 84/145 (57%), Gaps = 5/145 (3%)
Frame = +3
Query: 96 IQVWK---PHEKYEMLHILSK-GHKVVYSSAWYLDHLMSGGDWTNFYLSDPRQMVRQYSP 263
IQVW+ P + L +++K G + + S+ WYL+ + G DW +FY+ +P + + +P
Sbjct: 389 IQVWREDIPVNYMKELELVTKAGFRALLSAPWYLNRISYGPDWKDFYVVEP--LAFEGTP 446
Query: 264 TANVDNIVGGEACMWGEVVNDMNVISRIWSRASAVAERLWSPE-TEGLRYMNKVPNEVYS 440
++GGEACMWGE V++ N++ R+W RA AVAERLWS + T L + Y
Sbjct: 447 EQKA-LVIGGEACMWGEYVDNTNLVPRLWPRAGAVAERLWSNKLTSDLTF-------AYE 498
Query: 441 RLEEHTCRMNRRGIDAQPPSGPGFC 515
RL C + RRG+ AQ P GFC
Sbjct: 499 RLSHFRCELLRRGVQAQ-PLNVGFC 522
>BC001138-1|AAH01138.2| 409|Homo sapiens HEXA protein protein.
Length = 409
Score = 103 bits (246), Expect = 2e-21
Identities = 57/145 (39%), Positives = 84/145 (57%), Gaps = 5/145 (3%)
Frame = +3
Query: 96 IQVWK---PHEKYEMLHILSK-GHKVVYSSAWYLDHLMSGGDWTNFYLSDPRQMVRQYSP 263
IQVW+ P + L +++K G + + S+ WYL+ + G DW +FY+ +P + + +P
Sbjct: 269 IQVWREDIPVNYMKELELVTKAGFRALLSAPWYLNRISYGPDWKDFYVVEP--LAFEGTP 326
Query: 264 TANVDNIVGGEACMWGEVVNDMNVISRIWSRASAVAERLWSPE-TEGLRYMNKVPNEVYS 440
++GGEACMWGE V++ N++ R+W RA AVAERLWS + T L + Y
Sbjct: 327 EQKA-LVIGGEACMWGEYVDNTNLVPRLWPRAGAVAERLWSNKLTSDLTF-------AYE 378
Query: 441 RLEEHTCRMNRRGIDAQPPSGPGFC 515
RL C + RRG+ AQ P GFC
Sbjct: 379 RLSHFRCELLRRGVQAQ-PLNVGFC 402
>AK222502-1|BAD96222.1| 529|Homo sapiens hexosaminidase A
preproprotein variant protein.
Length = 529
Score = 103 bits (246), Expect = 2e-21
Identities = 57/145 (39%), Positives = 84/145 (57%), Gaps = 5/145 (3%)
Frame = +3
Query: 96 IQVWK---PHEKYEMLHILSK-GHKVVYSSAWYLDHLMSGGDWTNFYLSDPRQMVRQYSP 263
IQVW+ P + L +++K G + + S+ WYL+ + G DW +FY+ +P + + +P
Sbjct: 389 IQVWREDIPVNYMKELELVTKAGFRALLSAPWYLNRISYGPDWKDFYVVEP--LAFEGTP 446
Query: 264 TANVDNIVGGEACMWGEVVNDMNVISRIWSRASAVAERLWSPE-TEGLRYMNKVPNEVYS 440
++GGEACMWGE V++ N++ R+W RA AVAERLWS + T L + Y
Sbjct: 447 EQKA-LVIGGEACMWGEYVDNTNLVPRLWPRAGAVAERLWSNKLTSDLTF-------AYE 498
Query: 441 RLEEHTCRMNRRGIDAQPPSGPGFC 515
RL C + RRG+ AQ P GFC
Sbjct: 499 RLSHFRCELLRRGVQAQ-PLNVGFC 522
>M23294-1|AAA52645.1| 556|Homo sapiens beta-hexosaminidase
beta-subunit protein.
Length = 556
Score = 102 bits (244), Expect = 4e-21
Identities = 57/142 (40%), Positives = 79/142 (55%), Gaps = 2/142 (1%)
Frame = +3
Query: 96 IQVWKPHEKYEML-HILSKGHKVVYSSAWYLDHLMSGGDWTNFYLSDPRQMVRQYSPTAN 272
++VWK E L + + G V+ S+ WYLD + G DW +Y +P + T
Sbjct: 421 VEVWKDSAYPEELSRVTASGFPVILSAPWYLDLISYGQDWRKYYKVEPLD----FGGTQK 476
Query: 273 VDNI-VGGEACMWGEVVNDMNVISRIWSRASAVAERLWSPETEGLRYMNKVPNEVYSRLE 449
+ +GGEAC+WGE V+ N+ R+W RASAV ERLWS ++ +R M ++ Y RL
Sbjct: 477 QKQLFIGGEACLWGEYVDATNLTPRLWPRASAVGERLWS--SKDVRDM----DDAYDRLT 530
Query: 450 EHTCRMNRRGIDAQPPSGPGFC 515
H CRM RGI AQP G+C
Sbjct: 531 RHRCRMVERGIAAQPLYA-GYC 551
>M19735-1|AAA68620.1| 544|Homo sapiens beta-hexosaminidase
beta-subunit protein.
Length = 544
Score = 102 bits (244), Expect = 4e-21
Identities = 57/142 (40%), Positives = 79/142 (55%), Gaps = 2/142 (1%)
Frame = +3
Query: 96 IQVWKPHEKYEML-HILSKGHKVVYSSAWYLDHLMSGGDWTNFYLSDPRQMVRQYSPTAN 272
++VWK E L + + G V+ S+ WYLD + G DW +Y +P + T
Sbjct: 409 VEVWKDSAYPEELSRVTASGFPVILSAPWYLDLISYGQDWRKYYKVEPLD----FGGTQK 464
Query: 273 VDNI-VGGEACMWGEVVNDMNVISRIWSRASAVAERLWSPETEGLRYMNKVPNEVYSRLE 449
+ +GGEAC+WGE V+ N+ R+W RASAV ERLWS ++ +R M ++ Y RL
Sbjct: 465 QKQLFIGGEACLWGEYVDATNLTPRLWPRASAVGERLWS--SKDVRDM----DDAYDRLT 518
Query: 450 EHTCRMNRRGIDAQPPSGPGFC 515
H CRM RGI AQP G+C
Sbjct: 519 RHRCRMVERGIAAQPLYA-GYC 539
>M13519-1|AAA51828.1| 572|Homo sapiens HEXB protein.
Length = 572
Score = 102 bits (244), Expect = 4e-21
Identities = 57/142 (40%), Positives = 79/142 (55%), Gaps = 2/142 (1%)
Frame = +3
Query: 96 IQVWKPHEKYEML-HILSKGHKVVYSSAWYLDHLMSGGDWTNFYLSDPRQMVRQYSPTAN 272
++VWK E L + + G V+ S+ WYLD + G DW +Y +P + T
Sbjct: 437 VEVWKDSAYPEELSRVTASGFPVILSAPWYLDLISYGQDWRKYYKVEPLD----FGGTQK 492
Query: 273 VDNI-VGGEACMWGEVVNDMNVISRIWSRASAVAERLWSPETEGLRYMNKVPNEVYSRLE 449
+ +GGEAC+WGE V+ N+ R+W RASAV ERLWS ++ +R M ++ Y RL
Sbjct: 493 QKQLFIGGEACLWGEYVDATNLTPRLWPRASAVGERLWS--SKDVRDM----DDAYDRLT 546
Query: 450 EHTCRMNRRGIDAQPPSGPGFC 515
H CRM RGI AQP G+C
Sbjct: 547 RHRCRMVERGIAAQPLYA-GYC 567
>BT009919-1|AAP88921.1| 556|Homo sapiens hexosaminidase B (beta
polypeptide) protein.
Length = 556
Score = 102 bits (244), Expect = 4e-21
Identities = 57/142 (40%), Positives = 79/142 (55%), Gaps = 2/142 (1%)
Frame = +3
Query: 96 IQVWKPHEKYEML-HILSKGHKVVYSSAWYLDHLMSGGDWTNFYLSDPRQMVRQYSPTAN 272
++VWK E L + + G V+ S+ WYLD + G DW +Y +P + T
Sbjct: 421 VEVWKDSAYPEELSRVTASGFPVILSAPWYLDLISYGQDWRKYYKVEPLD----FGGTQK 476
Query: 273 VDNI-VGGEACMWGEVVNDMNVISRIWSRASAVAERLWSPETEGLRYMNKVPNEVYSRLE 449
+ +GGEAC+WGE V+ N+ R+W RASAV ERLWS ++ +R M ++ Y RL
Sbjct: 477 QKQLFIGGEACLWGEYVDATNLTPRLWPRASAVGERLWS--SKDVRDM----DDAYDRLT 530
Query: 450 EHTCRMNRRGIDAQPPSGPGFC 515
H CRM RGI AQP G+C
Sbjct: 531 RHRCRMVERGIAAQPLYA-GYC 551
>BC017378-1|AAH17378.1| 556|Homo sapiens hexosaminidase B (beta
polypeptide) protein.
Length = 556
Score = 102 bits (244), Expect = 4e-21
Identities = 57/142 (40%), Positives = 79/142 (55%), Gaps = 2/142 (1%)
Frame = +3
Query: 96 IQVWKPHEKYEML-HILSKGHKVVYSSAWYLDHLMSGGDWTNFYLSDPRQMVRQYSPTAN 272
++VWK E L + + G V+ S+ WYLD + G DW +Y +P + T
Sbjct: 421 VEVWKDSAYPEELSRVTASGFPVILSAPWYLDLISYGQDWRKYYKVEPLD----FGGTQK 476
Query: 273 VDNI-VGGEACMWGEVVNDMNVISRIWSRASAVAERLWSPETEGLRYMNKVPNEVYSRLE 449
+ +GGEAC+WGE V+ N+ R+W RASAV ERLWS ++ +R M ++ Y RL
Sbjct: 477 QKQLFIGGEACLWGEYVDATNLTPRLWPRASAVGERLWS--SKDVRDM----DDAYDRLT 530
Query: 450 EHTCRMNRRGIDAQPPSGPGFC 515
H CRM RGI AQP G+C
Sbjct: 531 RHRCRMVERGIAAQPLYA-GYC 551
>AY643499-1|AAV48875.1| 331|Homo sapiens ENC-1AS protein.
Length = 331
Score = 102 bits (244), Expect = 4e-21
Identities = 57/142 (40%), Positives = 79/142 (55%), Gaps = 2/142 (1%)
Frame = +3
Query: 96 IQVWKPHEKYEML-HILSKGHKVVYSSAWYLDHLMSGGDWTNFYLSDPRQMVRQYSPTAN 272
++VWK E L + + G V+ S+ WYLD + G DW +Y +P + T
Sbjct: 196 VEVWKDSAYPEELSRVTASGFPVILSAPWYLDLISYGQDWRKYYKVEPLD----FGGTQK 251
Query: 273 VDNI-VGGEACMWGEVVNDMNVISRIWSRASAVAERLWSPETEGLRYMNKVPNEVYSRLE 449
+ +GGEAC+WGE V+ N+ R+W RASAV ERLWS ++ +R M ++ Y RL
Sbjct: 252 QKQLFIGGEACLWGEYVDATNLTPRLWPRASAVGERLWS--SKDVRDM----DDAYDRLT 305
Query: 450 EHTCRMNRRGIDAQPPSGPGFC 515
H CRM RGI AQP G+C
Sbjct: 306 RHRCRMVERGIAAQPLYA-GYC 326
>AF378118-1|AAM46114.1| 556|Homo sapiens cervical cancer
proto-oncogene 7 protein.
Length = 556
Score = 102 bits (244), Expect = 4e-21
Identities = 57/142 (40%), Positives = 79/142 (55%), Gaps = 2/142 (1%)
Frame = +3
Query: 96 IQVWKPHEKYEML-HILSKGHKVVYSSAWYLDHLMSGGDWTNFYLSDPRQMVRQYSPTAN 272
++VWK E L + + G V+ S+ WYLD + G DW +Y +P + T
Sbjct: 421 VEVWKDSAYPEELSRVTASGFPVILSAPWYLDLISYGQDWRKYYKVEPLD----FGGTQK 476
Query: 273 VDNI-VGGEACMWGEVVNDMNVISRIWSRASAVAERLWSPETEGLRYMNKVPNEVYSRLE 449
+ +GGEAC+WGE V+ N+ R+W RASAV ERLWS ++ +R M ++ Y RL
Sbjct: 477 QKQLFIGGEACLWGEYVDATNLTPRLWPRASAVGERLWS--SKDVRDM----DDAYDRLT 530
Query: 450 EHTCRMNRRGIDAQPPSGPGFC 515
H CRM RGI AQP G+C
Sbjct: 531 RHRCRMVERGIAAQPLYA-GYC 551
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 142,686,038
Number of Sequences: 237096
Number of extensions: 2579846
Number of successful extensions: 12149
Number of sequences better than 10.0: 15
Number of HSP's better than 10.0 without gapping: 11955
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 12113
length of database: 76,859,062
effective HSP length: 94
effective length of database: 54,572,038
effective search space used: 23302260226
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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