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Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= BGIBMGA000062-TA|BGIBMGA000062-PA|IPR002529|Fumarylacetoacetate
(FAA) hydrolase
         (288 letters)

Database: uniref50 
           1,657,284 sequences; 575,637,011 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

UniRef50_Q2F601 Cluster: Fumarylacetoacetate hydrolase isoform A...   601   e-171
UniRef50_Q2F600 Cluster: Fumarylacetoacetate hydrolase isoform B...   340   2e-92
UniRef50_UPI000051A4FC Cluster: PREDICTED: similar to fumarylace...   275   7e-73
UniRef50_Q6P2I3 Cluster: Fumarylacetoacetate hydrolase domain-co...   256   4e-67
UniRef50_Q95SI7 Cluster: GH23390p; n=7; Coelomata|Rep: GH23390p ...   248   1e-64
UniRef50_UPI0000E821BC Cluster: PREDICTED: similar to CGI-105 pr...   244   2e-63
UniRef50_Q54BF3 Cluster: Putative uncharacterized protein; n=1; ...   229   5e-59
UniRef50_A4A1V1 Cluster: 2-keto-4-pentenoate hydratase/2-oxohept...   226   4e-58
UniRef50_A6CF17 Cluster: 2-keto-4-pentenoate hydratase/2-oxohept...   222   7e-57
UniRef50_A1WX00 Cluster: 5-carboxymethyl-2-hydroxymuconate delta...   211   1e-53
UniRef50_Q7UKL0 Cluster: 2-keto-4-pentenoate hydratase/2-oxohept...   208   9e-53
UniRef50_Q9KBC8 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate iso...   205   1e-51
UniRef50_Q1ATI0 Cluster: 5-carboxymethyl-2-hydroxymuconate delta...   204   2e-51
UniRef50_Q8ENN7 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate iso...   202   6e-51
UniRef50_A5V084 Cluster: 5-carboxymethyl-2-hydroxymuconate Delta...   201   1e-50
UniRef50_Q6N1I0 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate iso...   195   9e-49
UniRef50_Q1GTC2 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate de...   195   9e-49
UniRef50_Q01WN8 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate de...   195   1e-48
UniRef50_A7HTC6 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate de...   195   1e-48
UniRef50_Q1AZJ6 Cluster: 5-carboxymethyl-2-hydroxymuconate delta...   194   2e-48
UniRef50_A6EBW4 Cluster: 2-keto-4-pentenoate hydratase/2-oxohept...   192   7e-48
UniRef50_Q18A35 Cluster: Putative hydrolase; n=2; Clostridium di...   190   4e-47
UniRef50_Q1ITZ8 Cluster: 5-carboxymethyl-2-hydroxymuconate delta...   189   8e-47
UniRef50_A7CXW5 Cluster: 5-carboxymethyl-2-hydroxymuconate Delta...   189   8e-47
UniRef50_Q0B7L5 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate de...   187   3e-46
UniRef50_A1W846 Cluster: 5-carboxymethyl-2-hydroxymuconate delta...   185   1e-45
UniRef50_Q1GLV2 Cluster: 5-carboxymethyl-2-hydroxymuconate delta...   185   1e-45
UniRef50_Q5LLB0 Cluster: Fumarylacetoacetate hydrolase family pr...   184   2e-45
UniRef50_Q1VM36 Cluster: 2-keto-4-pentenoate hydratase/2-oxohept...   184   2e-45
UniRef50_A0KDR8 Cluster: 5-carboxymethyl-2-hydroxymuconate delta...   184   2e-45
UniRef50_Q12CU6 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate de...   184   2e-45
UniRef50_Q7W6X4 Cluster: Putative uncharacterized protein; n=2; ...   183   4e-45
UniRef50_A5MZU4 Cluster: Putative uncharacterized protein; n=1; ...   183   4e-45
UniRef50_Q5WIZ5 Cluster: 2-keto-4-pentenoate hydratase/2-oxohept...   181   2e-44
UniRef50_A4FCY5 Cluster: 5-carboxymethyl-2-hydroxymuconate delta...   181   2e-44
UniRef50_Q6I239 Cluster: Fumarylacetoacetate hydrolase family pr...   180   3e-44
UniRef50_A4V8P0 Cluster: Putative fumarylacetoacetate hydrolase ...   180   3e-44
UniRef50_Q7WM06 Cluster: Putative oxygenase; n=3; Bordetella|Rep...   180   4e-44
UniRef50_Q67K64 Cluster: Putative 2-hydroxyhepta-2,4-diene-1,7-d...   180   4e-44
UniRef50_Q2BPP6 Cluster: 5-carboxymethyl-2-hydroxymuconate delta...   180   5e-44
UniRef50_A6TKL2 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=...   178   2e-43
UniRef50_Q1YHR9 Cluster: Putative fumarylacetoacetate hydrolase;...   177   3e-43
UniRef50_A6TL34 Cluster: 5-carboxymethyl-2-hydroxymuconate Delta...   177   3e-43
UniRef50_Q89JJ8 Cluster: Blr5285 protein; n=7; Proteobacteria|Re...   177   4e-43
UniRef50_Q67SA7 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate iso...   176   5e-43
UniRef50_A0VVP4 Cluster: 5-carboxymethyl-2-hydroxymuconate delta...   175   1e-42
UniRef50_A2W1T8 Cluster: 2-keto-4-pentenoate hydratase/2-oxohept...   175   1e-42
UniRef50_Q0G5A5 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate iso...   174   2e-42
UniRef50_A1RQJ1 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate de...   174   2e-42
UniRef50_A4SYH8 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate de...   173   3e-42
UniRef50_Q0S8P7 Cluster: Probable hydrolase; n=1; Rhodococcus sp...   173   4e-42
UniRef50_Q41AV1 Cluster: 5-carboxymethyl-2-hydroxymuconate delta...   173   6e-42
UniRef50_A7IDT5 Cluster: 5-carboxymethyl-2-hydroxymuconate Delta...   173   6e-42
UniRef50_Q89GI5 Cluster: Bll6360 protein; n=157; Bacteria|Rep: B...   172   8e-42
UniRef50_Q0RCN1 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate iso...   172   8e-42
UniRef50_A0K0J6 Cluster: 5-carboxymethyl-2-hydroxymuconate delta...   172   1e-41
UniRef50_A3XC82 Cluster: 5-carboxymethyl-2-hydroxymuconate delta...   171   2e-41
UniRef50_Q4FMJ2 Cluster: Fumarylacetoacetate hydrolase family pr...   171   2e-41
UniRef50_Q5Z0F5 Cluster: Putative hydrolase; n=1; Nocardia farci...   169   5e-41
UniRef50_A5AB73 Cluster: Function: E. coli hpaG is a bifunctiona...   169   5e-41
UniRef50_Q4J809 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=...   169   5e-41
UniRef50_A7DRD3 Cluster: 5-carboxymethyl-2-hydroxymuconate Delta...   169   5e-41
UniRef50_A4SYK1 Cluster: Fumarylacetoacetate (FAA) hydrolase pre...   169   7e-41
UniRef50_Q7WM74 Cluster: Putative hydrolase; n=3; Burkholderiale...   169   9e-41
UniRef50_A3YEW7 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate de...   169   9e-41
UniRef50_Q8RCZ4 Cluster: 2-keto-4-pentenoate hydratase/2-oxohept...   168   1e-40
UniRef50_Q88Y59 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioateisom...   168   1e-40
UniRef50_A1DM45 Cluster: Fumarylacetoacetate hydrolase family pr...   168   1e-40
UniRef50_A0V486 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate de...   166   7e-40
UniRef50_Q2U1K8 Cluster: RIB40 genomic DNA, SC138; n=4; Pezizomy...   166   7e-40
UniRef50_A4WEA8 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate de...   165   9e-40
UniRef50_A3VFY9 Cluster: 5-carboxymethyl-2-hydroxymuconate delta...   165   9e-40
UniRef50_Q59050 Cluster: Uncharacterized protein MJ1656; n=4; Eu...   165   9e-40
UniRef50_O53242 Cluster: POSSIBLE 2-HYDROXYHEPTA-2,4-DIENE-1,7-D...   165   2e-39
UniRef50_Q2UMF8 Cluster: Predicted fumarylacetoacetate hydralase...   164   3e-39
UniRef50_A3IC16 Cluster: Fumarylacetoacetate hydrolase family pr...   163   4e-39
UniRef50_Q0C030 Cluster: Fumarylacetoacetate hydrolase family pr...   163   5e-39
UniRef50_Q0SJB3 Cluster: Possible fumarylacetoacetate hydrolase;...   163   6e-39
UniRef50_Q0C3X7 Cluster: Fumarylacetoacetate hydrolase family pr...   163   6e-39
UniRef50_A1SD71 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate de...   162   8e-39
UniRef50_A5VAQ6 Cluster: 5-carboxymethyl-2-hydroxymuconate Delta...   162   1e-38
UniRef50_Q11EA1 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=...   161   2e-38
UniRef50_Q9VU50 Cluster: CG11251-PA; n=1; Drosophila melanogaste...   161   2e-38
UniRef50_O27551 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate iso...   161   2e-38
UniRef50_Q8YDN8 Cluster: 2-HYDROXYHEPTA-2,4-DIENE-1,7-DIOATE ISO...   160   4e-38
UniRef50_A3LSP4 Cluster: Degradation of aromatic compounds; n=9;...   159   6e-38
UniRef50_Q6M0X4 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate de...   159   6e-38
UniRef50_UPI00015C5CCD Cluster: hypothetical protein CKO_03358; ...   158   2e-37
UniRef50_Q0V440 Cluster: Putative uncharacterized protein; n=1; ...   158   2e-37
UniRef50_Q46S57 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate de...   157   3e-37
UniRef50_A0HII6 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=...   157   3e-37
UniRef50_Q4L4Y4 Cluster: Uncharacterized protein SH1982; n=17; S...   157   3e-37
UniRef50_Q8Y512 Cluster: Lmo2266 protein; n=13; Listeria|Rep: Lm...   157   4e-37
UniRef50_A0QV79 Cluster: Fumarylacetoacetate hydrolase family pr...   157   4e-37
UniRef50_A5VE85 Cluster: 5-carboxymethyl-2-hydroxymuconate Delta...   156   5e-37
UniRef50_A3TUH0 Cluster: Fumarylacetoacetate hydrolase family pr...   156   5e-37
UniRef50_Q46NJ4 Cluster: 5-carboxymethyl-2-hydroxymuconate delta...   155   9e-37
UniRef50_Q9HK55 Cluster: Probable 2-hydroxyhepta-2, 4-diene-1, 7...   155   9e-37
UniRef50_Q6L066 Cluster: Fumarylacetoacetate hydrolase family pr...   155   9e-37
UniRef50_A0RY21 Cluster: 2-keto-4-pentenoate hydratase/2-oxohept...   155   1e-36
UniRef50_O28058 Cluster: Uncharacterized protein AF_2225; n=3; c...   155   2e-36
UniRef50_Q193D4 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=...   154   2e-36
UniRef50_A3KJW3 Cluster: Putative maleylpyruvate isomerase; n=1;...   153   5e-36
UniRef50_Q0CVN6 Cluster: Predicted protein; n=1; Aspergillus ter...   152   9e-36
UniRef50_A5NU93 Cluster: 5-carboxymethyl-2-hydroxymuconate Delta...   152   1e-35
UniRef50_A6NUP5 Cluster: Putative uncharacterized protein; n=1; ...   151   2e-35
UniRef50_A6CED1 Cluster: 5-carboxymethyl-2-hydroxymuconate delta...   151   2e-35
UniRef50_Q7ML43 Cluster: Putative uncharacterized protein VV1584...   151   2e-35
UniRef50_A5P4N8 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate de...   151   2e-35
UniRef50_UPI000023DA6E Cluster: hypothetical protein FG11179.1; ...   151   3e-35
UniRef50_Q313F7 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate de...   150   4e-35
UniRef50_A6M380 Cluster: 5-carboxymethyl-2-hydroxymuconate Delta...   149   8e-35
UniRef50_A2BJD1 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=...   149   8e-35
UniRef50_Q39LG9 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate de...   149   1e-34
UniRef50_Q0LZE6 Cluster: 5-carboxymethyl-2-hydroxymuconate delta...   147   3e-34
UniRef50_Q5KJF0 Cluster: Mitochondrion protein, putative; n=1; F...   146   4e-34
UniRef50_O58377 Cluster: Uncharacterized protein PH0643; n=4; Th...   146   6e-34
UniRef50_Q1IVB8 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate de...   146   8e-34
UniRef50_Q0S9S7 Cluster: Possible fumarylacetoacetate hydrolase;...   145   1e-33
UniRef50_Q0SFL0 Cluster: Maleylpyruvate isomerase; n=4; Actinomy...   144   2e-33
UniRef50_Q0LC36 Cluster: 5-carboxymethyl-2-hydroxymuconate delta...   144   2e-33
UniRef50_A5FQA8 Cluster: 5-carboxymethyl-2-hydroxymuconate Delta...   143   4e-33
UniRef50_Q5V4M0 Cluster: 2-hydroxyhepta-24-diene-1,7-dioate isom...   143   5e-33
UniRef50_Q13HB6 Cluster: Putative fumarylacetoacetate (FAA) hydr...   142   7e-33
UniRef50_A0LGT2 Cluster: 5-carboxymethyl-2-hydroxymuconate delta...   142   7e-33
UniRef50_A1SM04 Cluster: 5-carboxymethyl-2-hydroxymuconate delta...   142   9e-33
UniRef50_Q8NLC0 Cluster: 2-keto-4-pentenoate hydratase/2-oxohept...   140   3e-32
UniRef50_Q1M9K7 Cluster: Putative FAA hydrolase family protein; ...   140   3e-32
UniRef50_Q9HJ20 Cluster: 2-hydroxyhepta-2, 4-diene-1, 7-dioate i...   140   5e-32
UniRef50_A2QL54 Cluster: Contig An05c0060, complete genome; n=6;...   139   9e-32
UniRef50_Q74FM1 Cluster: Fumarylacetoacetate hydrolase family pr...   138   1e-31
UniRef50_Q8TWN0 Cluster: 2-keto-4-pentenoate hydratase hydratase...   138   1e-31
UniRef50_UPI000038DFF7 Cluster: hypothetical protein Faci_030014...   138   2e-31
UniRef50_Q9KBC3 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate iso...   138   2e-31
UniRef50_A7D5S8 Cluster: 5-carboxymethyl-2-hydroxymuconate delta...   138   2e-31
UniRef50_Q6BTI3 Cluster: Similar to CA3735|IPF5534 Candida albic...   138   2e-31
UniRef50_A3EQW7 Cluster: 2-keto-4-pentenoate hydratase/2-oxohept...   137   3e-31
UniRef50_Q6AFQ8 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate iso...   137   3e-31
UniRef50_A0QU69 Cluster: Fumarylacetoacetate hydrolase family pr...   137   3e-31
UniRef50_Q2USU7 Cluster: RIB40 genomic DNA, SC005; n=6; Pezizomy...   137   3e-31
UniRef50_Q7BRJ5 Cluster: DitM; n=5; Proteobacteria|Rep: DitM - P...   136   8e-31
UniRef50_Q09C56 Cluster: Fumarylacetoacetate hydrolase family pr...   136   8e-31
UniRef50_Q1MQ53 Cluster: 2-keto-4-pentenoate hydratase/2-oxohept...   135   1e-30
UniRef50_Q9RYT2 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate iso...   134   2e-30
UniRef50_Q6BTK5 Cluster: Similar to CA3735|IPF5534 Candida albic...   134   2e-30
UniRef50_Q5KN08 Cluster: Mitochondrion protein, putative; n=14; ...   134   2e-30
UniRef50_Q11E65 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=...   133   4e-30
UniRef50_Q5KZR6 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate iso...   133   6e-30
UniRef50_Q28U26 Cluster: 5-carboxymethyl-2-hydroxymuconate delta...   132   8e-30
UniRef50_A3YN46 Cluster: Fumarylacetoacetate hydrolase family pr...   132   8e-30
UniRef50_Q4JXJ3 Cluster: Putative 2-hydroxyhepta-2,4-diene-1,7-d...   132   1e-29
UniRef50_A4SYL9 Cluster: 5-carboxymethyl-2-hydroxymuconate Delta...   132   1e-29
UniRef50_Q11D77 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=...   132   1e-29
UniRef50_Q01DJ4 Cluster: Predicted fumarylacetoacetate hydralase...   132   1e-29
UniRef50_Q2NHN7 Cluster: Predicted 2-keto-4-pentenoate hydratase...   132   1e-29
UniRef50_Q46978 Cluster: 4-hydroxyphenylacetate degradation bifu...   132   1e-29
UniRef50_Q2S2N6 Cluster: Possible 2-hydroxyhepta-2,4-diene-1,7-d...   131   2e-29
UniRef50_A2QFQ2 Cluster: Remark: ORF contains 1 frameshift; n=3;...   128   2e-28
UniRef50_O30145 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate iso...   128   2e-28
UniRef50_P73637 Cluster: 5-oxo-1,2,5-tricarboxilic-3-penten acid...   127   3e-28
UniRef50_Q9X4X5 Cluster: DitD; n=3; Proteobacteria|Rep: DitD - P...   127   3e-28
UniRef50_Q3S4C0 Cluster: Putative hydratase; n=2; Proteobacteria...   127   4e-28
UniRef50_Q9F135 Cluster: Putative uncharacterized protein xlnF; ...   126   7e-28
UniRef50_Q5KAM1 Cluster: Mitochondrion protein, putative; n=3; E...   126   7e-28
UniRef50_Q7VGX9 Cluster: Putative uncharacterized protein; n=1; ...   126   9e-28
UniRef50_Q979A6 Cluster: 2-hydroxyhepta-2,4-diend-1,7-dioate iso...   124   2e-27
UniRef50_P34673 Cluster: Uncharacterized protein ZK688.3; n=5; E...   124   2e-27
UniRef50_Q66BX8 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate iso...   124   3e-27
UniRef50_A2U6Z6 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=...   123   5e-27
UniRef50_Q01NL2 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=...   122   8e-27
UniRef50_A5V6X8 Cluster: 5-carboxymethyl-2-hydroxymuconate Delta...   122   1e-26
UniRef50_A5V8P5 Cluster: 5-carboxymethyl-2-hydroxymuconate Delta...   121   2e-26
UniRef50_A7BDZ2 Cluster: Putative uncharacterized protein; n=1; ...   120   6e-26
UniRef50_Q1DXV6 Cluster: Putative uncharacterized protein; n=2; ...   120   6e-26
UniRef50_A0IRN0 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=...   119   1e-25
UniRef50_A5V6J4 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=...   118   1e-25
UniRef50_Q8G4X7 Cluster: Possible 2-hydroxyhepta-2,4-diene-1,7-d...   118   2e-25
UniRef50_Q9LBE3 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate iso...   118   2e-25
UniRef50_P76004 Cluster: Uncharacterized protein ycgM; n=41; Gam...   118   2e-25
UniRef50_Q8NQY2 Cluster: 2-keto-4-pentenoate hydratase/2-oxohept...   116   5e-25
UniRef50_Q5LT14 Cluster: Fumarylacetoacetate hydrolase family pr...   116   7e-25
UniRef50_A0HJM1 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=...   116   7e-25
UniRef50_A4WBF8 Cluster: 5-carboxymethyl-2-hydroxymuconate Delta...   116   9e-25
UniRef50_Q70P92 Cluster: MelH protein; n=3; Cystobacteraceae|Rep...   115   2e-24
UniRef50_Q6P587 Cluster: Fumarylacetoacetate hydrolase domain-co...   113   4e-24
UniRef50_Q81VG5 Cluster: Fumarylacetoacetate hydrolase family pr...   113   5e-24
UniRef50_A3Q487 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=...   113   7e-24
UniRef50_Q9YG48 Cluster: Fumarylacetoacetate hydrolase family pr...   113   7e-24
UniRef50_A1HMI6 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=...   111   2e-23
UniRef50_A0Y9R8 Cluster: 2-keto-4-pentenoate hydratase/2-oxohept...   111   2e-23
UniRef50_Q8EMH6 Cluster: 4-hydroxyphenylacetate degradation bifu...   110   5e-23
UniRef50_A6G0I9 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate de...   110   5e-23
UniRef50_A7EGL0 Cluster: 2-keto-4-pentenoate hydratase; n=6; Asc...   110   5e-23
UniRef50_Q6N2Q7 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=...   109   6e-23
UniRef50_Q1EC44 Cluster: IP02096p; n=6; Endopterygota|Rep: IP020...   109   6e-23
UniRef50_A0GN11 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=...   109   1e-22
UniRef50_A0UKA6 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=...   108   2e-22
UniRef50_A0QDN9 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate iso...   108   2e-22
UniRef50_Q6D4M4 Cluster: Fumarylacetoacetate hydrolase family pr...   107   2e-22
UniRef50_UPI000023E361 Cluster: hypothetical protein FG10641.1; ...   107   3e-22
UniRef50_Q4P0N7 Cluster: Putative uncharacterized protein; n=1; ...   107   4e-22
UniRef50_Q1AX83 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate de...   106   7e-22
UniRef50_A7D0K4 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=...   105   1e-21
UniRef50_Q1ATV1 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=...   104   2e-21
UniRef50_Q0K430 Cluster: 2-Keto-4-pentenoate hydratase/2-oxohept...   104   2e-21
UniRef50_Q7VXR8 Cluster: Putative hydrolase; n=1; Bordetella per...   104   3e-21
UniRef50_A6T028 Cluster: Faa-hydrolase family protein; n=7; Prot...   104   3e-21
UniRef50_Q397B1 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=...   103   4e-21
UniRef50_Q89QI2 Cluster: Bll3146 protein; n=11; Proteobacteria|R...   103   5e-21
UniRef50_Q72P81 Cluster: Fumarylacetoacetate hydrolase family pr...   103   5e-21
UniRef50_Q2G539 Cluster: 5-carboxymethyl-2-hydroxymuconate delta...   103   5e-21
UniRef50_A4CE53 Cluster: 2-keto-4-pentenoate hydratase/2-oxohept...   103   5e-21
UniRef50_Q7PYH5 Cluster: ENSANGP00000019097; n=2; Culicidae|Rep:...   103   5e-21
UniRef50_A6W1E0 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=...   102   9e-21
UniRef50_A3UWQ7 Cluster: Putative uncharacterized protein; n=1; ...   101   2e-20
UniRef50_Q28QQ6 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=...   100   4e-20
UniRef50_A0JY14 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=...   100   4e-20
UniRef50_Q9LUR3 Cluster: Isomerase-like protein; n=5; rosids|Rep...   100   5e-20
UniRef50_A1KUG3 Cluster: Putative hydrolase; n=4; Neisseria|Rep:...    99   6e-20
UniRef50_Q9P7L4 Cluster: Uncharacterized hydrolase C21C3.09c; n=...   100   9e-20
UniRef50_P53889 Cluster: Uncharacterized hydrolase YNL168C; n=7;...    99   1e-19
UniRef50_Q1I918 Cluster: 4-hydroxyphenylacetate degradation; 2-h...    99   1e-19
UniRef50_A6FIA8 Cluster: Fumarylacetoacetate hydrolase family pr...    98   3e-19
UniRef50_A2CBF2 Cluster: Putative uncharacterized protein; n=1; ...    97   3e-19
UniRef50_Q0TZ11 Cluster: Putative uncharacterized protein; n=1; ...    97   6e-19
UniRef50_Q1ATV3 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=...    95   1e-18
UniRef50_Q2I760 Cluster: PlaH; n=1; Streptomyces sp. Tu6071|Rep:...    95   2e-18
UniRef50_Q89D60 Cluster: Blr7583 protein; n=1; Bradyrhizobium ja...    94   3e-18
UniRef50_Q0VTE8 Cluster: Fumarylacetoacetate hydrolase family pr...    94   3e-18
UniRef50_A0QS23 Cluster: 5-carboxymethyl-2-hydroxymuconate delta...    94   4e-18
UniRef50_Q2W396 Cluster: 2-keto-4-pentenoate hydratase/2-oxohept...    93   6e-18
UniRef50_Q1GJL0 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=...    93   7e-18
UniRef50_A4F0I3 Cluster: Fumarylacetoacetate hydrolase family pr...    93   7e-18
UniRef50_Q6N496 Cluster: Possible isomerase/decarboxylase; n=4; ...    92   1e-17
UniRef50_A1SFW5 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=...    92   1e-17
UniRef50_Q5GXD7 Cluster: Fumarylacetoacetate hydrolase; n=8; Xan...    91   3e-17
UniRef50_Q1QDY9 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=...    91   3e-17
UniRef50_A6W055 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate de...    91   3e-17
UniRef50_Q7NUB2 Cluster: Probable isomerase; n=3; Betaproteobact...    91   4e-17
UniRef50_O86346 Cluster: POSSIBLE BIFUNCTIONAL ENZYME: 2-HYDROXY...    89   9e-17
UniRef50_A6D592 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=...    89   9e-17
UniRef50_A1VKI1 Cluster: Fumarylacetoacetate (FAA) hydrolase pre...    89   1e-16
UniRef50_Q5P741 Cluster: Fumarylpyruvate hydrolase; n=14; Proteo...    88   3e-16
UniRef50_Q3INL8 Cluster: Probable 2-hydroxyhepta-2,4-diene-1,7-d...    88   3e-16
UniRef50_A5VDV9 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=...    87   5e-16
UniRef50_A5VE51 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate de...    87   6e-16
UniRef50_Q4WH18 Cluster: Fumarylacetoacetate hydrolase family pr...    86   9e-16
UniRef50_A4YZ43 Cluster: Putative Fumarylacetoacetate hydrolase ...    85   1e-15
UniRef50_Q4WX41 Cluster: Fumarylacetoacetate hydrolase family pr...    85   1e-15
UniRef50_Q89FA1 Cluster: Bll6800 protein; n=3; Proteobacteria|Re...    85   2e-15
UniRef50_Q9X4X0 Cluster: DitH; n=8; Proteobacteria|Rep: DitH - P...    85   2e-15
UniRef50_Q1VYL9 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate iso...    85   2e-15
UniRef50_Q8KDK4 Cluster: Fumarylacetoacetate hydrolase family pr...    85   3e-15
UniRef50_Q4AQ85 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=...    85   3e-15
UniRef50_Q2BPV1 Cluster: Putative uncharacterized protein; n=4; ...    83   1e-14
UniRef50_A6E756 Cluster: Fumarylacetoacetate hydrolase family pr...    83   1e-14
UniRef50_A3PZU8 Cluster: 5-carboxymethyl-2-hydroxymuconate delta...    83   1e-14
UniRef50_A4SV99 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=...    82   1e-14
UniRef50_A5V6I4 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=...    82   2e-14
UniRef50_Q0LGD1 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=...    80   6e-14
UniRef50_A1HJ09 Cluster: 5-carboxymethyl-2-hydroxymuconate delta...    80   6e-14
UniRef50_UPI00006CDD7C Cluster: fumarylacetoacetate hydrolase fa...    79   1e-13
UniRef50_Q5KVH0 Cluster: Hypothetical conserved protein; n=2; Ge...    79   1e-13
UniRef50_A3SNB2 Cluster: Fumarylacetoacetate hydrolase family pr...    79   1e-13
UniRef50_Q22Y44 Cluster: Fumarylacetoacetate hydrolase family pr...    79   1e-13
UniRef50_Q15XL1 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=...    79   1e-13
UniRef50_Q3WGU5 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=...    78   2e-13
UniRef50_A5V0Z8 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=...    77   4e-13
UniRef50_Q44SK1 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=...    77   7e-13
UniRef50_A3VRL8 Cluster: Putative isomerase-decarboxylase-like p...    77   7e-13
UniRef50_Q88M65 Cluster: Fumarylacetoacetate hydrolase family pr...    76   9e-13
UniRef50_Q97UR1 Cluster: 2-hydroxyhepta-2 ,4-diene-1,7-dioate is...    76   1e-12
UniRef50_A2U2G0 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate iso...    75   2e-12
UniRef50_A0GBX8 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=...    73   6e-12
UniRef50_Q6MNK0 Cluster: Putative uncharacterized protein; n=1; ...    72   1e-11
UniRef50_A5EF32 Cluster: Putative Fumarylacetoacetate (FAA) hydr...    72   2e-11
UniRef50_Q6F7V5 Cluster: Putative uncharacterized protein; n=2; ...    71   3e-11
UniRef50_A1UG87 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=...    71   3e-11
UniRef50_Q0SB97 Cluster: Possible fumarylacetoacetate hydrolase ...    71   5e-11
UniRef50_Q5B6D4 Cluster: Putative uncharacterized protein; n=1; ...    71   5e-11
UniRef50_Q0AN49 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=...    70   6e-11
UniRef50_A4EDA6 Cluster: Putative 2-hydroxyhepta-2,4-diene-1,7-d...    70   6e-11
UniRef50_Q7MXX3 Cluster: Fumarylacetoacetate hydrolase family pr...    69   1e-10
UniRef50_Q0S954 Cluster: Possible hydratase; n=3; Actinomycetale...    69   1e-10
UniRef50_Q6KZ97 Cluster: Fumarylacetoacetase; n=2; Thermoplasmat...    69   1e-10
UniRef50_Q395G4 Cluster: 5-carboxymethyl-2-hydroxymuconate delta...    69   2e-10
UniRef50_A0VBW0 Cluster: 4-hydroxyphenylacetate degradation bifu...    69   2e-10
UniRef50_Q4D6U8 Cluster: Putative uncharacterized protein; n=2; ...    67   4e-10
UniRef50_A4QX03 Cluster: Putative uncharacterized protein; n=1; ...    66   7e-10
UniRef50_A1TDQ7 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=...    65   2e-09
UniRef50_Q18X79 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=...    64   3e-09
UniRef50_Q9CKS8 Cluster: HpaG; n=1; Pasteurella multocida|Rep: H...    63   7e-09
UniRef50_Q2W964 Cluster: 2-keto-4-pentenoate hydratase/2-oxohept...    63   7e-09
UniRef50_Q0HT13 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=...    63   7e-09
UniRef50_Q97VT9 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate iso...    63   9e-09
UniRef50_Q3II31 Cluster: Putative fumarylacetoacetate hydrolase ...    62   2e-08
UniRef50_A5VED2 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate de...    61   3e-08
UniRef50_Q5UY90 Cluster: 2-hydroxyhepta-24-diene-1,7-dioate isom...    61   3e-08
UniRef50_A7D1J1 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=...    61   3e-08
UniRef50_Q7WPF0 Cluster: Putative fumarylacetoacetate hydrolase ...    61   4e-08
UniRef50_Q60C48 Cluster: Fumarylacetoacetate hydrolase family pr...    61   4e-08
UniRef50_Q7UMG2 Cluster: Probable 2-hydroxyhepta-2,4-diene-1,7-d...    60   8e-08
UniRef50_A3VNC8 Cluster: Possible isomerase/decarboxylase; n=1; ...    60   8e-08
UniRef50_Q1GRD3 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=...    58   2e-07
UniRef50_A6C0W6 Cluster: Probable 2-hydroxyhepta-2,4-diene-1,7-d...    58   2e-07
UniRef50_Q4FWM5 Cluster: Putative uncharacterized protein; n=3; ...    57   5e-07
UniRef50_A7K1Y8 Cluster: Fumarylacetoacetate hydrolase family pr...    56   1e-06
UniRef50_Q2UV71 Cluster: Predicted protein; n=1; Aspergillus ory...    55   2e-06
UniRef50_Q8D6F8 Cluster: 2-keto-4-pentenoate hydratase; n=22; Pr...    55   2e-06
UniRef50_Q4J6K3 Cluster: 4-hydroxyphenylacetate degradation bifu...    55   2e-06
UniRef50_Q02AF6 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=...    54   3e-06
UniRef50_A6Q508 Cluster: Fumarylacetoacetate hydrolase family pr...    53   1e-05
UniRef50_A1SUQ4 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=...    52   1e-05
UniRef50_Q9KDZ0 Cluster: BH1071 protein; n=2; Bacillus|Rep: BH10...    51   3e-05
UniRef50_Q5KYI4 Cluster: Hypothetical conserved protein; n=3; Ba...    50   5e-05
UniRef50_A2UC21 Cluster: 2-keto-4-pentenoate hydratase/2-oxohept...    50   5e-05
UniRef50_Q5V2I1 Cluster: Fumarylacetoacetate hydrolase family pr...    50   5e-05
UniRef50_A6Q9W9 Cluster: Fumarylacetoacetate hydrolase; n=1; Sul...    48   3e-04
UniRef50_A7QL05 Cluster: Chromosome undetermined scaffold_116, w...    48   3e-04
UniRef50_Q1AYK9 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=...    46   0.001
UniRef50_A6GCP0 Cluster: Putative uncharacterized protein; n=1; ...    45   0.003
UniRef50_A3IA41 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=...    45   0.003
UniRef50_Q4J7I6 Cluster: Conserved protein; n=3; Thermoprotei|Re...    43   0.008
UniRef50_A0SP98 Cluster: Fumarylacetoacetate hydrolase family pr...    42   0.018
UniRef50_Q5DHL1 Cluster: SJCHGC00506 protein; n=2; Schistosoma j...    42   0.024
UniRef50_Q3E159 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=...    41   0.042
UniRef50_A3HUE1 Cluster: Probable 2-hydroxyhepta-2,4-diene-1,7-d...    41   0.042
UniRef50_O65374 Cluster: F12F1.8 protein; n=7; Eukaryota|Rep: F1...    40   0.074
UniRef50_Q5B250 Cluster: Putative uncharacterized protein; n=1; ...    39   0.13 
UniRef50_A4CGG1 Cluster: Probable 2-hydroxyhepta-2,4-diene-1,7-d...    38   0.30 
UniRef50_Q4RJI4 Cluster: Chromosome 3 SCAF15037, whole genome sh...    37   0.68 
UniRef50_Q2HI94 Cluster: Putative uncharacterized protein; n=1; ...    36   0.91 
UniRef50_A6RA82 Cluster: Predicted protein; n=5; Eurotiomycetida...    36   0.91 
UniRef50_Q39M11 Cluster: Fumarylacetoacetase; n=17; Bacteria|Rep...    36   1.6  
UniRef50_A6VYW9 Cluster: Fumarylacetoacetase; n=2; Proteobacteri...    36   1.6  
UniRef50_Q10JF6 Cluster: Isomerase, putative; n=10; Magnoliophyt...    36   1.6  
UniRef50_Q6MTK5 Cluster: Na+ ABC transporter, ATP-binding compon...    35   2.8  
UniRef50_Q6EMI8 Cluster: Fumarylacetoacetase; n=16; Proteobacter...    34   3.7  
UniRef50_A5ZTI1 Cluster: Sensor protein; n=1; Ruminococcus obeum...    34   3.7  
UniRef50_A7SBM4 Cluster: Predicted protein; n=1; Nematostella ve...    34   3.7  
UniRef50_A6QYE5 Cluster: Predicted protein; n=1; Ajellomyces cap...    34   3.7  
UniRef50_Q64UD6 Cluster: Putative uracil permease; n=2; Bacteroi...    34   4.8  
UniRef50_A7ED04 Cluster: Putative uncharacterized protein; n=1; ...    34   4.8  
UniRef50_Q4HNG9 Cluster: Putative uncharacterized protein; n=1; ...    33   6.4  
UniRef50_Q13GK9 Cluster: Putative fumarylacetoacetate hydrolase;...    33   6.4  
UniRef50_Q54XC7 Cluster: Putative uncharacterized protein; n=1; ...    33   6.4  
UniRef50_UPI0000E21965 Cluster: PREDICTED: similar to pol protei...    33   8.4  
UniRef50_Q7W190 Cluster: Fumarylacetoacetase; n=9; Proteobacteri...    33   8.4  
UniRef50_A7Q3E6 Cluster: Chromosome chr13 scaffold_48, whole gen...    33   8.4  
UniRef50_A7KV72 Cluster: Putative metalloprotein chaperonin subu...    33   8.4  

>UniRef50_Q2F601 Cluster: Fumarylacetoacetate hydrolase isoform A;
           n=1; Bombyx mori|Rep: Fumarylacetoacetate hydrolase
           isoform A - Bombyx mori (Silk moth)
          Length = 330

 Score =  601 bits (1485), Expect = e-171
 Identities = 288/288 (100%), Positives = 288/288 (100%)

Query: 1   MKLVQFSYKDSPKNIRVGYLEGDDIVDINKADSSLPTTLLQILRNGDLEKVKKLKSTKPA 60
           MKLVQFSYKDSPKNIRVGYLEGDDIVDINKADSSLPTTLLQILRNGDLEKVKKLKSTKPA
Sbjct: 43  MKLVQFSYKDSPKNIRVGYLEGDDIVDINKADSSLPTTLLQILRNGDLEKVKKLKSTKPA 102

Query: 61  TIPLSSVTLTAPIHGVDKILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRI 120
           TIPLSSVTLTAPIHGVDKILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRI
Sbjct: 103 TIPLSSVTLTAPIHGVDKILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRI 162

Query: 121 RTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLLG 180
           RTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLLG
Sbjct: 163 RTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLLG 222

Query: 181 KSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMT 240
           KSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMT
Sbjct: 223 KSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMT 282

Query: 241 LVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIGAFDVRIEKF 288
           LVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIGAFDVRIEKF
Sbjct: 283 LVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIGAFDVRIEKF 330


>UniRef50_Q2F600 Cluster: Fumarylacetoacetate hydrolase isoform B;
           n=1; Bombyx mori|Rep: Fumarylacetoacetate hydrolase
           isoform B - Bombyx mori (Silk moth)
          Length = 360

 Score =  340 bits (836), Expect = 2e-92
 Identities = 162/162 (100%), Positives = 162/162 (100%)

Query: 127 KVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLLGKSMDTF 186
           KVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLLGKSMDTF
Sbjct: 199 KVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLLGKSMDTF 258

Query: 187 CPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPGDL 246
           CPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPGDL
Sbjct: 259 CPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPGDL 318

Query: 247 ILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIGAFDVRIEKF 288
           ILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIGAFDVRIEKF
Sbjct: 319 ILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIGAFDVRIEKF 360


>UniRef50_UPI000051A4FC Cluster: PREDICTED: similar to
           fumarylacetoacetate hydrolase domain containing 2A
           isoform 2; n=1; Apis mellifera|Rep: PREDICTED: similar
           to fumarylacetoacetate hydrolase domain containing 2A
           isoform 2 - Apis mellifera
          Length = 334

 Score =  275 bits (675), Expect = 7e-73
 Identities = 130/283 (45%), Positives = 190/283 (67%), Gaps = 5/283 (1%)

Query: 1   MKLVQFSYKDS-PKNIRVGYLEGDDIVDINKADSSLPTTLLQILRNGD--LEKVKKLKST 57
           M+ VQF+ K+  P+++ V  ++G DI+ ++  DS +P TL + L  GD  L+K K++ + 
Sbjct: 46  MRFVQFTGKNGGPQHLGVQLVQGGDIIAVSAVDSRIPNTLKKFLEGGDDLLKKAKRIVAE 105

Query: 58  KPATIPLSSVTLTAPIHGVDKILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQP 117
             + IP   V   AP+  +DK+ C+GLNY  HC+EQ ++PP  P++FSKF+S IIGP   
Sbjct: 106 GRSVIPEVEVNFLAPVTRMDKLACVGLNYIGHCKEQGVSPPESPVIFSKFASNIIGPRDN 165

Query: 118 VRIRTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEK-NMGQ 176
           + +   ++ KVDWE EL +V+G++   +   +   ++ GYT+AQDI+ARDWQK K N GQ
Sbjct: 166 IML-PPISDKVDWEAELAIVIGKKCKALNNNEGEDYIFGYTIAQDITARDWQKSKRNGGQ 224

Query: 177 FLLGKSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRIS 236
           FLLGK+MDTFCPLGP V+T + +     L V   +NG +KQ  +T++L+     ++  IS
Sbjct: 225 FLLGKAMDTFCPLGPAVVTKEAISDINNLTVKTWVNGNIKQDGNTSELIFKPHEIVAYIS 284

Query: 237 SVMTLVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIG 279
             MTL+PGD+ILTGTP GVG  R+PPEYLQ GDVL +EI+ +G
Sbjct: 285 QFMTLLPGDVILTGTPSGVGFTRKPPEYLQRGDVLETEIQGLG 327


>UniRef50_Q6P2I3 Cluster: Fumarylacetoacetate hydrolase
           domain-containing protein 2B; n=41; cellular
           organisms|Rep: Fumarylacetoacetate hydrolase
           domain-containing protein 2B - Homo sapiens (Human)
          Length = 314

 Score =  256 bits (628), Expect = 4e-67
 Identities = 116/260 (44%), Positives = 175/260 (67%), Gaps = 3/260 (1%)

Query: 22  GDDIVDINKADSSLPTTLLQILRNGD--LEKVKKLKSTKPATIPLSSVTLTAPIHGVDKI 79
           G  ++++N  D +LP T+ Q L  G+  L   ++  + +   +P S VT  AP+   DK+
Sbjct: 49  GGGVINLNAFDPTLPKTMTQFLEQGEATLSVARRALAAQLPVLPWSEVTFLAPVTWPDKV 108

Query: 80  LCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRIRTDVTKKVDWEVELCVVVG 139
           +C+G+NY DHC+EQN+  P  P++FSKF+S+I+GP   V +    +++VDWEVEL VV+G
Sbjct: 109 VCVGMNYVDHCKEQNVPVPKEPIIFSKFASSIVGPYDEV-VLPPQSQEVDWEVELAVVIG 167

Query: 140 REASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLLGKSMDTFCPLGPCVLTSDEV 199
           ++   ++  DA+ HVAG+TVA D+SARDW   +N  Q+LLGK+ DTFCPLGP ++T D V
Sbjct: 168 KKGKHIKATDAMAHVAGFTVAHDVSARDWLTRRNGKQWLLGKTFDTFCPLGPALVTKDSV 227

Query: 200 GAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPGDLILTGTPGGVGMYR 259
                L++ C +NG + QSS+T Q+V     L+  +S  +T  PGD+ILTGTP GVG++R
Sbjct: 228 ADPHNLKICCRVNGEVVQSSNTNQMVFKTEDLIAWVSQFVTFYPGDVILTGTPPGVGVFR 287

Query: 260 QPPEYLQPGDVLTSEIEKIG 279
           +PP +L+ GD +  EIE++G
Sbjct: 288 KPPVFLKKGDEVQCEIEELG 307


>UniRef50_Q95SI7 Cluster: GH23390p; n=7; Coelomata|Rep: GH23390p -
           Drosophila melanogaster (Fruit fly)
          Length = 293

 Score =  248 bits (607), Expect = 1e-64
 Identities = 128/281 (45%), Positives = 178/281 (63%), Gaps = 4/281 (1%)

Query: 1   MKLVQFSYKDSPKNIRVGYLEGDDIVDINKAD-SSLPTTL-LQILRNGDLEKVKKLKSTK 58
           M+ VQ+  K      R+G L  D    +  A    +P+ L + I ++ +LE++ K    +
Sbjct: 6   MRFVQYLRKGDLAK-RLGLLSEDQKSLVEFAGLEGVPSDLKILIAQDPNLEELAKKAEKQ 64

Query: 59  PATIPLSSVTLTAPIHGVDKILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPV 118
           P       VTL  P+    KI+CIGLNY+DHC EQN   P  P+ FSKF++ ++GP   V
Sbjct: 65  PRLEVNDDVTLLPPLTDPGKIICIGLNYQDHCDEQNKPTPKEPLFFSKFNNALVGPQDNV 124

Query: 119 RIRTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFL 178
            I    + K+DWEVEL  V+G+ A  V +  A+ +V GY+VAQDISARDWQKE+N GQFL
Sbjct: 125 -IAHAASSKIDWEVELVCVIGKVARQVPKSQAMDYVFGYSVAQDISARDWQKERNGGQFL 183

Query: 179 LGKSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSV 238
           +GKSMDTF PLGP V+    V     L +   +NGV KQ+ +T  L+  +  +++R+S  
Sbjct: 184 MGKSMDTFLPLGPAVVHKSLVPDVYNLNLKTWVNGVEKQNGNTGNLIFKLDDVINRLSQT 243

Query: 239 MTLVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIG 279
           +TL+PGD+I+TGTP GVGM+R PPE+LQPGDV+ SEI  +G
Sbjct: 244 ITLLPGDIIVTGTPKGVGMHRTPPEFLQPGDVVQSEIVGLG 284


>UniRef50_UPI0000E821BC Cluster: PREDICTED: similar to CGI-105
           protein; n=2; Gallus gallus|Rep: PREDICTED: similar to
           CGI-105 protein - Gallus gallus
          Length = 406

 Score =  244 bits (597), Expect = 2e-63
 Identities = 106/218 (48%), Positives = 154/218 (70%), Gaps = 1/218 (0%)

Query: 62  IPLSSVTLTAPIHGVDKILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRIR 121
           +P + V L API   +K++C+GLNY+DHC EQ++  P  P++FSKF S I GP   + + 
Sbjct: 183 LPRAGVRLLAPIDDPEKVICVGLNYRDHCLEQDVKVPKEPLIFSKFPSAIAGPFDDI-VH 241

Query: 122 TDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLLGK 181
              + +VDWEVEL  ++G+    ++E  A++H+ G+TVA D+SARDWQ  +N  Q+LLGK
Sbjct: 242 PAESSEVDWEVELAAIIGKTGRHIQESVAMEHIVGFTVANDVSARDWQMRRNGRQWLLGK 301

Query: 182 SMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTL 241
           + DTFCP+GP ++T D V     LR+ CS+NG L QSSST QL+  +P L+  +S  +TL
Sbjct: 302 TFDTFCPIGPAIVTKDSVTDVHNLRIRCSVNGQLMQSSSTNQLIFRLPQLVAWVSQFVTL 361

Query: 242 VPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIG 279
            PGD++LTGTP GVG++R+PP +L+PGD +  EIE++G
Sbjct: 362 RPGDVLLTGTPPGVGVFRKPPMFLKPGDEVQCEIEELG 399


>UniRef50_Q54BF3 Cluster: Putative uncharacterized protein; n=1;
           Dictyostelium discoideum AX4|Rep: Putative
           uncharacterized protein - Dictyostelium discoideum AX4
          Length = 305

 Score =  229 bits (561), Expect = 5e-59
 Identities = 121/293 (41%), Positives = 181/293 (61%), Gaps = 15/293 (5%)

Query: 1   MKLVQFSYKDSPKNIRVGYLEGDDIVDINKADSSLPTTLLQILRNGDLEKVKK----LKS 56
           +KLV +      ++ R+G L  + I+D+  AD S+P  +   L     +K  K    + +
Sbjct: 9   IKLVTYIPNVGEQSKRLGALLENSIIDLCSADKSIPNDMRSFLSLNSTDKWSKVINVINN 68

Query: 57  TKPATIPLSSVTLTAPIHGVDKILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQ 116
                IP+ +  + API    KI+CIGLNYK+H  E  +  P  P+VFSKF + I GP+ 
Sbjct: 69  INNRRIPIENCKIKAPIEP-GKIICIGLNYKEHANEAKMAIPKEPIVFSKFDNAICGPND 127

Query: 117 PVRIRTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQ 176
            + I+   + +VD+EVEL VV+G++A  V E DALQ+VAGYTV  D+SARDWQ  KN  Q
Sbjct: 128 SI-IKPVESDEVDYEVELVVVIGKQAKNVSESDALQYVAGYTVGNDVSARDWQLRKNNSQ 186

Query: 177 FLLGKSMDTFCPLGPCVLTSDEVGAAVE--------LRVSCSLNGVLKQSSSTAQLVHSI 228
           +LLGK+ DTF P+GP ++ + EV A  +        L + C+LNG + Q+S+T + + +I
Sbjct: 187 WLLGKTFDTFAPIGPSIVINPEVAALSDDTYFDPNNLSIKCTLNGQVVQNSTTKEFIFNI 246

Query: 229 PSLLHRISSVMTLVPGDLILTGTPGGVGMYRQP-PEYLQPGDVLTSEIEKIGA 280
            +++  +S + TL PGD+I TGTP GVG  R+P P +L+ GDV+  EIE++G+
Sbjct: 247 QTVVSYLSKLFTLNPGDIIFTGTPSGVGFIRKPNPIFLKSGDVIKCEIEELGS 299


>UniRef50_A4A1V1 Cluster: 2-keto-4-pentenoate
           hydratase/2-oxohepta-3-ene-1,7-dioic acidhydratase; n=1;
           Blastopirellula marina DSM 3645|Rep: 2-keto-4-pentenoate
           hydratase/2-oxohepta-3-ene-1,7-dioic acidhydratase -
           Blastopirellula marina DSM 3645
          Length = 284

 Score =  226 bits (553), Expect = 4e-58
 Identities = 118/286 (41%), Positives = 166/286 (58%), Gaps = 6/286 (2%)

Query: 1   MKLVQFSYKDSPKNIRVGYLEGDDIVDINKADSSLPTTLLQILRNGDLEKVKKLKSTKPA 60
           M+LV +  +  P   R     GDD +D++  D +LPT +  +L  GD+ + K L + +  
Sbjct: 1   MRLVTYQSEAGP---RAAVARGDDFIDLHHTDHTLPTDMKSLLALGDVAREKVLAAREHG 57

Query: 61  T-IPLSSVTLTAPIHGVDKILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVR 119
             IP  S  LT PI    K++C+GLNY DH +E   T    P++F+KF S +I     + 
Sbjct: 58  DPIPAGSRILT-PIINPQKVICVGLNYADHAKETGATVGDEPVIFNKFPSALIADHDEIH 116

Query: 120 IRTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLL 179
           +  + + +VD+E EL V +G     + + +A+ HV GY    DISARDWQK K   Q+LL
Sbjct: 117 LPPE-SSQVDYEAELVVAIGTAGKHIPQGEAMSHVGGYCCGNDISARDWQKGKPGKQWLL 175

Query: 180 GKSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVM 239
           GK+ DTF PLGP + T DE+     L + C LNG   Q SST+QL+  I  L+  +S+V+
Sbjct: 176 GKTFDTFAPLGPVLYTPDEIADPNNLAIRCRLNGETMQESSTSQLIFKIDFLISYLSNVV 235

Query: 240 TLVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIGAFDVRI 285
            L PGDLI TGTP GVG+ R P  +LQPGD +  EIE +G    R+
Sbjct: 236 MLQPGDLIFTGTPHGVGVARDPQVFLQPGDQVEVEIEGLGLLTNRV 281


>UniRef50_A6CF17 Cluster: 2-keto-4-pentenoate
           hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase;
           n=1; Planctomyces maris DSM 8797|Rep:
           2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic
           acid hydratase - Planctomyces maris DSM 8797
          Length = 290

 Score =  222 bits (543), Expect = 7e-57
 Identities = 113/261 (43%), Positives = 162/261 (62%), Gaps = 2/261 (0%)

Query: 27  DINKADSSLPTTLLQILR-NGDLEKVKKLKSTKPATIPLSSVTLTAPIHGVDKILCIGLN 85
           D++  D +LP +L  IL   G LE+ K             + TL API    K+LCIGLN
Sbjct: 28  DLSAFDENLPRSLKGILAVEGGLERAKAAAEQAQQADRQITGTLLAPIPSPGKVLCIGLN 87

Query: 86  YKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRIRTDVTKKVDWEVELCVVVGREASCV 145
           Y+DH +E  +  P  P+ FSKFSS++ G  QP+RI + V ++VD+E EL  V+G+    V
Sbjct: 88  YRDHAEETGMPFPDEPVCFSKFSSSVTGSGQPIRIPS-VAREVDYEAELVAVIGKTCRNV 146

Query: 146 REEDALQHVAGYTVAQDISARDWQKEKNMGQFLLGKSMDTFCPLGPCVLTSDEVGAAVEL 205
            + +A  +VAGY    D+SARDWQ  +  GQ+LLGK+ DTF P GP ++T+DE+  A  L
Sbjct: 147 TQANASDYVAGYMNGHDVSARDWQIGRPGGQWLLGKTADTFAPTGPYLVTADEIKNANSL 206

Query: 206 RVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPGDLILTGTPGGVGMYRQPPEYL 265
            +  +LNG + Q+S+T + + +I  ++  +S ++TL PGD+I TGTP GVGM R+PP YL
Sbjct: 207 SIKLTLNGEVLQNSNTDKFIFTIEEVIAFVSQILTLEPGDIIFTGTPPGVGMARKPPVYL 266

Query: 266 QPGDVLTSEIEKIGAFDVRIE 286
           QPGD    EI+ +G     +E
Sbjct: 267 QPGDQACIEIQGLGMLHNTVE 287


>UniRef50_A1WX00 Cluster: 5-carboxymethyl-2-hydroxymuconate
           delta-isomerase; n=2; Ectothiorhodospiraceae|Rep:
           5-carboxymethyl-2-hydroxymuconate delta-isomerase -
           Halorhodospira halophila (strain DSM 244 / SL1)
           (Ectothiorhodospirahalophila (strain DSM 244 / SL1))
          Length = 316

 Score =  211 bits (516), Expect = 1e-53
 Identities = 104/231 (45%), Positives = 145/231 (62%), Gaps = 9/231 (3%)

Query: 62  IPLSSVTLTAPI-HGVDKILCIGLNYKDHCQEQN------LTPPPVPMVFSKFSSTIIGP 114
           +   ++T  AP+ H    ++C+GLNY DH +E        L  P  P+VF+K ++++ GP
Sbjct: 83  VTAEALTFLAPLPHPPRNVICLGLNYADHARESQQAKGDELALPEAPVVFTKATTSVAGP 142

Query: 115 DQPVRIRTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNM 174
                +   VT ++DWEVEL VV+GR    +RE+DALQHV GYTV  D+SARD Q     
Sbjct: 143 YDDFILDPSVTSELDWEVELAVVIGRGGRHIREQDALQHVFGYTVVNDLSARDLQFRHK- 201

Query: 175 GQFLLGKSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHR 234
            QF LGKS+D  CP+GP + T++ V     L +SC +N   +Q S T ++V SIP ++  
Sbjct: 202 -QFFLGKSVDGSCPMGPWITTANAVPNPHNLALSCRINDTTEQQSHTGEMVFSIPRIIAE 260

Query: 235 ISSVMTLVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIGAFDVRI 285
           +S VMTL+PGD+I TGTP GVG  R PP +LQ GD++TSE+E +G    RI
Sbjct: 261 LSRVMTLIPGDIIATGTPAGVGFARTPPRFLQAGDIVTSEVEGLGTLRNRI 311


>UniRef50_Q7UKL0 Cluster: 2-keto-4-pentenoate
           hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase;
           n=1; Pirellula sp.|Rep: 2-keto-4-pentenoate
           hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase -
           Rhodopirellula baltica
          Length = 342

 Score =  208 bits (509), Expect = 9e-53
 Identities = 102/214 (47%), Positives = 134/214 (62%), Gaps = 1/214 (0%)

Query: 69  LTAPIHGVDKILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRIRTDVTKKV 128
           L  P+   +KILCIGLNY DH  E     P +P+VFSKF+S ++G  Q + +   ++ KV
Sbjct: 123 LLPPVTCPEKILCIGLNYLDHAIETGAEKPSLPVVFSKFNSALVGHGQDI-VLPKISDKV 181

Query: 129 DWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLLGKSMDTFCP 188
           D+E EL VV+G+    V   +A+  V GY V  D+S+RDWQK +  GQ+L+GKS DTF P
Sbjct: 182 DYEAELVVVIGKTVRHVDANEAMDAVFGYAVGHDVSSRDWQKGRPGGQWLVGKSFDTFAP 241

Query: 189 LGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPGDLIL 248
           LGP V+T+DE+     L +   +NG   Q S T QL+  IP+L+  +S  MTL PGDLI 
Sbjct: 242 LGPAVVTADEISDPGNLPIRLHINGETLQESKTDQLIFDIPALIAHLSKFMTLKPGDLIF 301

Query: 249 TGTPGGVGMYRQPPEYLQPGDVLTSEIEKIGAFD 282
           TGTP GVG  R PP YL PGD    EI+ IG  +
Sbjct: 302 TGTPSGVGDARTPPRYLAPGDRCVVEIDGIGRLE 335


>UniRef50_Q9KBC8 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate
           isomerase; n=3; cellular organisms|Rep:
           2-hydroxyhepta-2,4-diene-1,7-dioate isomerase - Bacillus
           halodurans
          Length = 319

 Score =  205 bits (500), Expect = 1e-51
 Identities = 119/314 (37%), Positives = 188/314 (59%), Gaps = 34/314 (10%)

Query: 1   MKLVQFSYKDSPKNIRVGYLEGDDIVDINKA-----------------DSSLPTTLLQIL 43
           MK++ +  KD   ++R+G + G+ ++D+N+A                 D+ +P   L  L
Sbjct: 1   MKIINYRSKD---HVRIGCVIGNYVIDLNRAYAAMLEAQGLAKANEIADAVVPANSLSFL 57

Query: 44  RNGD---LEKVKKLKST-KPATIPLSS-------VTLTAPIHGVDKILCIGLNYKDHCQE 92
             G+   LE  K ++S  K    P  S       V   API    KI+C+G NY++H  E
Sbjct: 58  EGGEHTFLEASKAVQSIQKNELTPDQSKVFHEREVKKEAPILNSKKIICVGHNYREHILE 117

Query: 93  QNLTPPPVPMVFSKFSSTIIGPDQPVRIRTDVTKKVDWEVELCVVVGREASCVREEDALQ 152
                P  P++F+KF++TIIGP+  V + + +T+++D+E EL  V+G++A  V +EDAL 
Sbjct: 118 MKREIPKYPVIFAKFANTIIGPEDNVPLPS-ITEQLDYEAELAFVIGKKAKDVAKEDALD 176

Query: 153 HVAGYTVAQDISARDWQKEKNMGQFLLGKSMDTFCPLGPCVLTSDEVGAAVELRVSCSLN 212
           +VAGYT+  DI+ARD Q+     Q+L GK++D   P+GP ++T DE+    +L ++ S+N
Sbjct: 177 YVAGYTIVNDITARDLQRRTI--QWLQGKTLDGSLPMGPWLVTKDEIPNPHQLEITLSVN 234

Query: 213 GVLKQSSSTAQLVHSIPSLLHRISSVMTLVPGDLILTGTPGGVGMYRQPPEYLQPGDVLT 272
           G  +Q S+T  LV SI  L+  +S +MTL PGD++ TGTPGGVG+ R+P  +LQ GDV+ 
Sbjct: 235 GEERQRSNTKNLVFSIQDLVVFLSGIMTLEPGDVVCTGTPGGVGVAREPQLFLQDGDVVR 294

Query: 273 SEIEKIGAFDVRIE 286
            E+EK+G  + R++
Sbjct: 295 IELEKVGTLENRVK 308


>UniRef50_Q1ATI0 Cluster: 5-carboxymethyl-2-hydroxymuconate
           delta-isomerase; n=1; Rubrobacter xylanophilus DSM
           9941|Rep: 5-carboxymethyl-2-hydroxymuconate
           delta-isomerase - Rubrobacter xylanophilus (strain DSM
           9941 / NBRC 16129)
          Length = 295

 Score =  204 bits (499), Expect = 2e-51
 Identities = 100/218 (45%), Positives = 142/218 (65%), Gaps = 2/218 (0%)

Query: 62  IPLSSVTLTAPIHGVDKILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRIR 121
           +PL    L AP+    KI+ IGLNY+DH  E     P  P+VF+K+++T++G  + VRI 
Sbjct: 71  VPLEEARLHAPVLNPQKIIAIGLNYEDHANETGAPIPEKPIVFAKYANTLVGAGEEVRI- 129

Query: 122 TDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLLGK 181
             +T + D+E EL VV+GREA  V EE+AL++V GYT   D+S+RD Q  +  GQ+   K
Sbjct: 130 PPITSQADYEAELAVVIGREAKNVSEEEALEYVFGYTNCNDVSSRDLQFSEG-GQWTRSK 188

Query: 182 SMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTL 241
           S+DTFCPLGP V T DE+     LR+   LNG + Q S+T++++  +  L+  +S+ MTL
Sbjct: 189 SLDTFCPLGPYVATRDEIPDPQSLRIRSVLNGEVMQDSNTSKMIFPVARLISFLSTGMTL 248

Query: 242 VPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIG 279
           VPGD+I TGTP GVG  R P  +L+ GD ++ EIE +G
Sbjct: 249 VPGDIIATGTPAGVGFARDPKVFLKDGDEISIEIEGLG 286


>UniRef50_Q8ENN7 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate
           isomerase; n=1; Oceanobacillus iheyensis|Rep:
           2-hydroxyhepta-2,4-diene-1,7-dioate isomerase -
           Oceanobacillus iheyensis
          Length = 301

 Score =  202 bits (494), Expect = 6e-51
 Identities = 113/303 (37%), Positives = 179/303 (59%), Gaps = 19/303 (6%)

Query: 1   MKLVQFSYKDSPKNIRVGYL-EGDDIVDINKADS----------SLPTTLLQILRNGD-- 47
           MKLV +  K+S  + R+G++ + +++VD++ A             LP       + G   
Sbjct: 1   MKLVSYRKKESDSSFRMGFITDNEEVVDVHLASQHAIQAGNTTIELPFQPELFYQKGQDF 60

Query: 48  LEKVKKL---KSTKPATIPLSSVTLTAPIHGVDKILCIGLNYKDHCQEQNLTPPPVPMVF 104
           +++  KL    + +  T  L+ + L  P+    K++C+G NY +H  E     P  P++F
Sbjct: 61  IDEATKLFGSSNHRDFTYSLNEIQLGMPLGTARKVICVGKNYAEHVAEMKSEIPEFPVLF 120

Query: 105 SKFSSTIIGPDQPVRIRTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDIS 164
           +KF + IIGP++ +   + +T+K+D+EVEL +V+GREAS V EE+AL +VAGYT+  D S
Sbjct: 121 AKFDNAIIGPEEEIHY-SSLTEKLDYEVELTIVIGREASHVFEEEALDYVAGYTIGNDTS 179

Query: 165 ARDWQKEKNMGQFLLGKSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQL 224
           ARD QK     Q+L GKS+D   P+GP V+T DE+     L ++  +N   +Q S+T  L
Sbjct: 180 ARDLQKRTP--QWLQGKSLDHTTPIGPWVVTKDEIVDPGNLTIASYVNNEKRQYSNTKHL 237

Query: 225 VHSIPSLLHRISSVMTLVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIGAFDVR 284
           + S+P L+  IS+++TL PGD+I+TGTP GVG    PP Y++  D +  EIE IG  +  
Sbjct: 238 IFSVPYLVSFISNLITLKPGDIIMTGTPDGVGFAMDPPGYVKDKDKVKLEIEGIGIMENM 297

Query: 285 IEK 287
           ++K
Sbjct: 298 VKK 300


>UniRef50_A5V084 Cluster: 5-carboxymethyl-2-hydroxymuconate
           Delta-isomerase; n=2; Roseiflexus|Rep:
           5-carboxymethyl-2-hydroxymuconate Delta-isomerase -
           Roseiflexus sp. RS-1
          Length = 288

 Score =  201 bits (491), Expect = 1e-50
 Identities = 109/293 (37%), Positives = 173/293 (59%), Gaps = 17/293 (5%)

Query: 1   MKLVQFSYKDSPKNIRVGYLEGDDIVDINKADSSLPTTLLQILRNGDLE-KVKKLKSTKP 59
           M+LV  +Y+DS +++ +G L GD++V +    + +   +L ++  G    +  +    + 
Sbjct: 1   MRLV--TYRDS-ESVHLGALRGDEVVSL----ADVAPDMLSLIDAGPAGLEAARAAVERG 53

Query: 60  ATIPLSSVTLTAPI-HGVDKILCIGLNYKDHCQE----QNLTP--PPVPMVFSKFSSTII 112
           A +PLS+VTL API      ++C+G+NY  H  E    +   P  P  P+ F+K + T+ 
Sbjct: 54  AGVPLSAVTLLAPIPRPRQNVICLGMNYVAHTIESYRARGREPKMPEYPVFFTKAAHTVC 113

Query: 113 GPDQPVRIRTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEK 172
           GPD  + +   VT ++D+EVEL  ++G+    V  ++A+++V GYT+  DISARD Q   
Sbjct: 114 GPDDDIPLDPKVTNELDYEVELAFIIGKAGMNVPRDEAMEYVFGYTIVNDISARDLQSRH 173

Query: 173 NMGQFLLGKSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLL 232
              QF  GKS+   CP+GPC++T+DE+     L +   LNG  +Q S T  L+  IP+++
Sbjct: 174 Q--QFFKGKSLYRACPMGPCIVTTDEIPNPAGLGIRLRLNGETRQDSHTGDLIFDIPAII 231

Query: 233 HRISSVMTLVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIGAFDVRI 285
             +S  M L PG ++ TGTP GVG+ R PPEY++PGDV+ +EI+ IG    RI
Sbjct: 232 EHLSLGMPLEPGMIVATGTPAGVGLGRTPPEYMRPGDVMEAEIDSIGILRNRI 284


>UniRef50_Q6N1I0 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate
           isomerase; n=13; Proteobacteria|Rep:
           2-hydroxyhepta-2,4-diene-1,7-dioate isomerase -
           Rhodopseudomonas palustris
          Length = 280

 Score =  195 bits (476), Expect = 9e-49
 Identities = 97/211 (45%), Positives = 135/211 (63%), Gaps = 2/211 (0%)

Query: 69  LTAPIHGVDKILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRIRTDVTKKV 128
           L +P+ G  K + IGLNY DH  E N+  P  P+VF K  +++ GP+  V      TK +
Sbjct: 63  LGSPVGGAPKFIAIGLNYADHAAEANMPIPAEPIVFMKAINSLCGPNDDVEKPRGSTK-L 121

Query: 129 DWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLLGKSMDTFCP 188
           DWEVEL V++G  A  V E DAL +VAGY V  D+S R++Q E+  GQ+  GKS DTF P
Sbjct: 122 DWEVELAVIIGTRAKYVTEADALNYVAGYAVCNDVSERNFQLER-AGQWTKGKSHDTFGP 180

Query: 189 LGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPGDLIL 248
           LGP V T DE+    +L +   +NG  +Q+ STA ++ ++P ++  +S +MTL+PGD+I 
Sbjct: 181 LGPWVATKDEIADVHKLGMWLDVNGQRRQTGSTATMIFNVPKIVSYLSELMTLMPGDIIT 240

Query: 249 TGTPGGVGMYRQPPEYLQPGDVLTSEIEKIG 279
           TGTP GVG   +PP+YL  GDV+T  IE +G
Sbjct: 241 TGTPPGVGTGMKPPQYLNVGDVVTLGIEGLG 271


>UniRef50_Q1GTC2 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate
           decarboxylase; n=3; Bacteria|Rep:
           5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase -
           Sphingopyxis alaskensis (Sphingomonas alaskensis)
          Length = 302

 Score =  195 bits (476), Expect = 9e-49
 Identities = 112/292 (38%), Positives = 167/292 (57%), Gaps = 22/292 (7%)

Query: 7   SYKDSPKNIRVGYLEGDDIVDIN----KADSSLPTTLLQILRNGDLEKV---KKLKSTKP 59
           +Y+      R+G L    ++D++         LP+T+L  +  G +      + ++S  P
Sbjct: 5   TYRTVETEPRLGLLHDGLVIDVDYFGDAIGQDLPSTMLDFIDLGPIGPRFLREAVESATP 64

Query: 60  A-----TIPLSSVTLTAPIHGVDK-ILCIGLNYKDHCQEQNLTP------PPVPMVFSKF 107
           A     ++P  +VTL API    K I  IGLNY +H  E           P  P++FSK 
Sbjct: 65  ADLLGTSLPQGNVTLLAPIPRPRKNIFGIGLNYTEHVAESARALDTAHELPQQPVIFSKP 124

Query: 108 SSTIIGPDQPVRIRTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARD 167
            + +   + P+R    VT+++DWE EL V++G  A  V E DAL HV GYTV  D+SARD
Sbjct: 125 PTAVAAWNDPIRHNAKVTQQLDWETELAVIIGSTARGVAEADALNHVFGYTVINDVSARD 184

Query: 168 WQKEKNMGQFLLGKSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHS 227
            ++    GQ+++ K  D+F P+GPC++T+DE+G    L +   +NGV KQ+S+T  ++ +
Sbjct: 185 CRRA---GQWIVSKGQDSFAPMGPCIVTADEIGDPHNLNILTHVNGVEKQNSNTRFMLFN 241

Query: 228 IPSLLHRISSVMTLVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIG 279
           +P L+  I+ VMTL PGD+I TGTP GVG  R P E+L PGDV+   +E IG
Sbjct: 242 VPQLIADIARVMTLEPGDIIATGTPAGVGAGRDPQEFLWPGDVVECTVEGIG 293


>UniRef50_Q01WN8 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate
           decarboxylase; n=1; Solibacter usitatus Ellin6076|Rep:
           5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase -
           Solibacter usitatus (strain Ellin6076)
          Length = 269

 Score =  195 bits (475), Expect = 1e-48
 Identities = 91/216 (42%), Positives = 141/216 (65%), Gaps = 3/216 (1%)

Query: 64  LSSVTLTAPIHGVDKILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRIRTD 123
           ++ + L +P+    KI+CIGLNY+DH +E  +  P  P VF+K+ +T+ G   P+ +  +
Sbjct: 47  VAGMKLRSPLQRPGKIICIGLNYRDHAEEAKMPIPETPTVFAKWGNTVTGHQHPIVLPKN 106

Query: 124 VTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLLGKSM 183
            ++K D+E EL VV+G+    + E +  +HV GYT+  D+SARD+Q   +  Q+ +GK+ 
Sbjct: 107 -SRKPDYEAELAVVIGKGGRHIAEANWREHVFGYTILNDVSARDFQMATS--QWTIGKTF 163

Query: 184 DTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVP 243
           DTF P+GP ++T+DE+     LR+S +LN V  Q S+T+ L+  IP L+  +SSVM+L P
Sbjct: 164 DTFAPIGPWIVTTDEIEDPGALRISLTLNSVTMQDSNTSNLIFGIPKLIAYLSSVMSLEP 223

Query: 244 GDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIG 279
           GD+I TGTP GVG  ++PP +L PGDV   ++  IG
Sbjct: 224 GDIISTGTPAGVGFAQKPPRWLVPGDVCAIQVGGIG 259


>UniRef50_A7HTC6 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate
           decarboxylase; n=3; Proteobacteria|Rep:
           5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase -
           Parvibaculum lavamentivorans DS-1
          Length = 291

 Score =  195 bits (475), Expect = 1e-48
 Identities = 108/286 (37%), Positives = 165/286 (57%), Gaps = 8/286 (2%)

Query: 1   MKLVQFSYKDSPKNIRVGYLEGDDIVDINKADSSLPTTLLQILRN-GDLEKVKKLKSTKP 59
           MKL  FS   S   +R+G +  D IVD++KA   LP  +  ++ N   L + +++ +   
Sbjct: 1   MKLATFSEGGS---VRIGVVRDDGIVDLSKAAPELPRDMKSLIGNEAALARAREV-AKGG 56

Query: 60  ATIPLSSVTLTAPIHGVDKILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVR 119
           A +PLS+V L API    K+L IGLNY+DH +E     P   + F+K  + I GP   + 
Sbjct: 57  AALPLSAVKLLAPIPNPGKVLAIGLNYRDHVEESGQPMPEHQVWFNKQHNCITGPYADIA 116

Query: 120 IRTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLL 179
           + + V+  +D+E E+C V+G+    V +E A + +AGY V  D+S RDWQ   N  Q  +
Sbjct: 117 LPS-VSAFLDYEAEMCFVIGKRCKHVPKERAHEVIAGYFVGDDVSVRDWQLRTNTWQ--I 173

Query: 180 GKSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVM 239
           GKS DT  P+GP ++T DEVG    L + C +NG L+Q+S+T  L+      +  ++   
Sbjct: 174 GKSFDTHGPIGPWIVTPDEVGDPHALDIKCWVNGELRQNSNTKHLIFDCFDQIAHLTQAF 233

Query: 240 TLVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIGAFDVRI 285
           TL  GD+I TGT GG+G   +P + L+ GDV+  E+EK+G  + R+
Sbjct: 234 TLDIGDVIFTGTSGGIGAAMKPMQLLKEGDVVRVEVEKLGYIENRV 279


>UniRef50_Q1AZJ6 Cluster: 5-carboxymethyl-2-hydroxymuconate
           delta-isomerase; n=1; Rubrobacter xylanophilus DSM
           9941|Rep: 5-carboxymethyl-2-hydroxymuconate
           delta-isomerase - Rubrobacter xylanophilus (strain DSM
           9941 / NBRC 16129)
          Length = 293

 Score =  194 bits (474), Expect = 2e-48
 Identities = 106/280 (37%), Positives = 162/280 (57%), Gaps = 15/280 (5%)

Query: 16  RVGYLEGDDIVDINKADSSLPTTLLQILRNGD--LEKVKKLKSTKPATIPLSSVTLTAPI 73
           RVG +    +VD++    S+    L+++  G   LE+ + + +       L  V L API
Sbjct: 12  RVGAVVDGGVVDLSGRFGSM----LELIEGGGEALEEARAVAAGSGPAARLDEVRLLAPI 67

Query: 74  HGVDK-ILCIGLNYKDHCQE-------QNLTPPPVPMVFSKFSSTIIGPDQPVRIRTDVT 125
               + + C+G NY  H +E       Q    P  P  F K ++T+IGP   +    + +
Sbjct: 68  PQPRRNVFCMGWNYLTHFEEGRGRREGQGEELPEYPTFFDKPTTTVIGPHDDIPFDPNFS 127

Query: 126 KKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLLGKSMDT 185
           +K+D+E EL VV+GR    +   +A+ HV GYT A D++ARD Q+ ++ GQ+L GK MD 
Sbjct: 128 EKIDYEAELAVVIGRSGRSIPAGEAMDHVFGYTAANDVTARDVQR-RHGGQWLKGKGMDG 186

Query: 186 FCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPGD 245
            CPLGP ++T+DE+     L+V C +NGV KQ+S+T  +V  +  L+  +S  MTL+PGD
Sbjct: 187 SCPLGPWIVTADEIPDVQNLQVQCRVNGVQKQNSNTRFMVFPVARLIEELSLAMTLLPGD 246

Query: 246 LILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIGAFDVRI 285
           ++LTGTP GVG  R PPE+L+PGD +T  +E +G    R+
Sbjct: 247 VLLTGTPEGVGYARTPPEFLRPGDEVTVYVEGVGEISNRV 286


>UniRef50_A6EBW4 Cluster: 2-keto-4-pentenoate
           hydratase/2-oxohepta-3-ene-1 7-dioic acid hydratase;
           n=1; Pedobacter sp. BAL39|Rep: 2-keto-4-pentenoate
           hydratase/2-oxohepta-3-ene-1 7-dioic acid hydratase -
           Pedobacter sp. BAL39
          Length = 285

 Score =  192 bits (469), Expect = 7e-48
 Identities = 93/211 (44%), Positives = 137/211 (64%), Gaps = 2/211 (0%)

Query: 69  LTAPIHGVDKILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRIRTDVTKKV 128
           L +PI    K++CIGLNY DH +E N   PP P+VF K ++ I+GP   + I    + K 
Sbjct: 65  LGSPIGRPSKLVCIGLNYADHARETNAPLPPEPVVFMKSTTAIVGPFDQIMIPKG-SVKT 123

Query: 129 DWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLLGKSMDTFCP 188
           DWEVEL +V+G++AS V E +AL +VAGY +  D+S R++Q E+N G +  GK  DTF P
Sbjct: 124 DWEVELAIVIGKKASYVEEAEALDYVAGYVLHNDVSEREFQIERN-GTWDKGKGCDTFAP 182

Query: 189 LGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPGDLIL 248
           LGP + T +E+     LR+  S+NG + Q  +T+  + ++P ++  +S  MTL+PGD+I 
Sbjct: 183 LGPFLATKEEIADVNNLRLWLSVNGKMMQDGNTSNFIFNVPFVVSYVSQFMTLLPGDVIS 242

Query: 249 TGTPGGVGMYRQPPEYLQPGDVLTSEIEKIG 279
           TGTP GVG+  +PP YL+ GDV+   I+ +G
Sbjct: 243 TGTPAGVGLGFKPPVYLKAGDVVELGIDGLG 273


>UniRef50_Q18A35 Cluster: Putative hydrolase; n=2; Clostridium
           difficile|Rep: Putative hydrolase - Clostridium
           difficile (strain 630)
          Length = 294

 Score =  190 bits (463), Expect = 4e-47
 Identities = 110/290 (37%), Positives = 166/290 (57%), Gaps = 14/290 (4%)

Query: 1   MKLVQFSYKDSPKNIRVGYLEGDDIVDINKAD-SSLPTTLLQILRN---GDLEKVKKLKS 56
           MK V F   +  K I V   E + I +IN    S L T +   + N   GDLEK+K    
Sbjct: 1   MKFVTFCSSNEEK-IGVFNSETNSIYEINSLGLSKLYTDMNDFIENVSTGDLEKIKNNSF 59

Query: 57  TKPATIPLSSVTLTAPIHGVDK-ILCIGLNYKDHCQE------QNLTPPPVPMVFSKFSS 109
                  L  V L +PI    K I+C+GLNYKDH  E      +N+  P  P+ FSK + 
Sbjct: 60  ENAKCYKLEEVKLCSPIVRPKKDIICLGLNYKDHVNEIPDGVIKNVVMPDYPIYFSKRAD 119

Query: 110 TIIGPDQPVRIRTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQ 169
            IIG D  + +  D+ +K+D+E EL V++G+E   + +EDA +++ GYT+  DIS R  Q
Sbjct: 120 KIIGVDDKISLHGDLVEKLDYESELAVIIGKEGINISKEDAYEYIFGYTIVNDISERALQ 179

Query: 170 KEKNMGQFLLGKSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIP 229
            +K++ Q+  GKS+DT   +GPC++  +E    ++L +S  +NG ++Q S+T   +  IP
Sbjct: 180 -DKHV-QWFRGKSLDTHTSMGPCIVHKEEFEHPLKLDISSVVNGEVRQDSNTEYFIFDIP 237

Query: 230 SLLHRISSVMTLVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIG 279
           ++++ +S  MTL PGD+I TGTP GV M   P  YL+ GD++  ++E IG
Sbjct: 238 TIINDLSRGMTLKPGDIISTGTPAGVAMGMNPQVYLKHGDIVECKVEGIG 287


>UniRef50_Q1ITZ8 Cluster: 5-carboxymethyl-2-hydroxymuconate
           delta-isomerase; n=1; Acidobacteria bacterium
           Ellin345|Rep: 5-carboxymethyl-2-hydroxymuconate
           delta-isomerase - Acidobacteria bacterium (strain
           Ellin345)
          Length = 290

 Score =  189 bits (460), Expect = 8e-47
 Identities = 117/296 (39%), Positives = 172/296 (58%), Gaps = 17/296 (5%)

Query: 1   MKLVQFSYKDSPKNIRVGYLEGDD-IVDINKA------DSSLPTTLLQILRNGD--LEKV 51
           M+LVQ  Y+ + ++ R+G + GD   VD+  A      D++   + L +L +G   LE V
Sbjct: 1   MRLVQ--YRANGES-RLGLVVGDGAFVDVASAAEKAGRDAAPFQSTLALLESGPDALEFV 57

Query: 52  KKLKSTKPATIPLSSVTLTAPIHGVDKILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTI 111
           + L       + +    L  P+    KI+ IGLNY DH +E   + P  P+ F+KF+S++
Sbjct: 58  RTL-GVGQDVVHVDGRDLDFPV-AAKKIVAIGLNYLDHAKEAGQSIPKTPLCFAKFTSSL 115

Query: 112 IGPDQPVRIRTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKE 171
            GP  P+R+  D   +VD+E EL VV+G+ A  V E +A+++VAGY V  D+S R  Q  
Sbjct: 116 SGPYDPIRL-PDAEAQVDFEGELGVVIGKRAHRVAESEAMEYVAGYVVFNDVSERRSQFA 174

Query: 172 KNMGQFLLGKSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSL 231
              GQ+  GKS DTF P GP ++T DEV     LR++  +NG + Q S+T QL+  IP L
Sbjct: 175 D--GQWTRGKSCDTFSPNGPYLVTRDEVADPGNLRITTRVNGAVMQDSNTNQLIFKIPEL 232

Query: 232 LHRISSVMTLVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIGAFDVRIEK 287
           +  +S   T  PGD+I TGTP GVG  R+PP YL+ GD++  EIE +G    R+E+
Sbjct: 233 ISYLSHSFTFHPGDIIATGTPPGVGFSRKPPLYLREGDLVEVEIESVGRIANRVER 288


>UniRef50_A7CXW5 Cluster: 5-carboxymethyl-2-hydroxymuconate
           Delta-isomerase; n=1; Opitutaceae bacterium TAV2|Rep:
           5-carboxymethyl-2-hydroxymuconate Delta-isomerase -
           Opitutaceae bacterium TAV2
          Length = 279

 Score =  189 bits (460), Expect = 8e-47
 Identities = 88/205 (42%), Positives = 133/205 (64%), Gaps = 1/205 (0%)

Query: 79  ILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRIRTDV-TKKVDWEVELCVV 137
           ILCIGLNY+ H +E +   P  P++F K  + +  P  P+ + T + + +VD+E EL VV
Sbjct: 69  ILCIGLNYRRHAEETHARIPEFPVLFMKGVNALQNPGDPIMLPTHLRSDEVDYECELAVV 128

Query: 138 VGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLLGKSMDTFCPLGPCVLTSD 197
           +GR    V  + AL +V GYT A D+SARDWQ ++   Q+  GK+ DTF PLGP ++T D
Sbjct: 129 IGRTCKNVTRDHALDYVLGYTCANDVSARDWQVKRGGSQWCRGKTFDTFAPLGPAIVTKD 188

Query: 198 EVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPGDLILTGTPGGVGM 257
           E+     L++S +++G + Q  +T+ ++  +P+L+  +S   TL+PG +ILTGTP GVGM
Sbjct: 189 EIPNPNALKISTTVSGEVLQDWTTSDMIFDVPALIEFLSGSTTLLPGTVILTGTPHGVGM 248

Query: 258 YRQPPEYLQPGDVLTSEIEKIGAFD 282
            R+PP +L+ GD +  EIEKIG  +
Sbjct: 249 ARKPPRWLRAGDKVVVEIEKIGRLE 273


>UniRef50_Q0B7L5 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate
           decarboxylase; n=6; Proteobacteria|Rep:
           5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase -
           Burkholderia cepacia (strain ATCC 53795 / AMMD)
          Length = 291

 Score =  187 bits (455), Expect = 3e-46
 Identities = 103/284 (36%), Positives = 164/284 (57%), Gaps = 11/284 (3%)

Query: 1   MKLVQFSYKDSPKNIRVGYLEGDDIVDINKADSSLPTTLLQILRNG-DLEKVKKLKSTKP 59
           MKL+ F       + R+G L+G D++D+N+AD ++P  L   L  G D+    +  +T+ 
Sbjct: 1   MKLITFKQNG---DTRLGVLDGSDVIDLNRADPAVPADLRAALEAGVDVVAAARNAATRA 57

Query: 60  AT---IPLSSVTLTAPIHGVDKILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQ 116
                IPLS V L   +    KI+C+G N+ DH +E     P  P++F + ++++I    
Sbjct: 58  DVGNRIPLSEVELAPVVPKPGKIVCLGHNFYDHAKEGGNLKPVYPLIFFRGATSLIAHGD 117

Query: 117 PVRIRTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQ 176
           PV IR  V++K+D+E EL VV+G+    V+ E+AL HV GY    D+S RD+QK     Q
Sbjct: 118 PV-IRPFVSEKLDYEAELVVVIGKTGRHVKRENALDHVFGYACFNDVSVRDYQKRT--AQ 174

Query: 177 FLLGKSMDTFCPLGPCVLTSDEVG-AAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRI 235
           + +GK+ D     GP ++TSDE+   A  L++   LNG   Q ++TA ++ S+   +  +
Sbjct: 175 WTIGKNFDGTGAFGPWLVTSDELPPGAAGLKLELRLNGEAMQRANTADMIWSVAETIELL 234

Query: 236 SSVMTLVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIG 279
           +  +TL PGD+++ GTP GVG  R PP +++ GD +  +IE IG
Sbjct: 235 TECLTLEPGDVVVMGTPAGVGFARTPPVWMKAGDRVEVDIEGIG 278


>UniRef50_A1W846 Cluster: 5-carboxymethyl-2-hydroxymuconate
           delta-isomerase; n=2; Proteobacteria|Rep:
           5-carboxymethyl-2-hydroxymuconate delta-isomerase -
           Acidovorax sp. (strain JS42)
          Length = 281

 Score =  185 bits (451), Expect = 1e-45
 Identities = 95/214 (44%), Positives = 128/214 (59%), Gaps = 5/214 (2%)

Query: 59  PATIPLSSVTLTAPIHGVDKILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPV 118
           PA +P     L  P+ GV KI+C+GLNY DH  E  L  P  P++F K +S + GP   V
Sbjct: 55  PAVVP--GTRLGCPVGGVGKIVCVGLNYADHAAEAGLPAPAEPVLFMKATSALSGPTDAV 112

Query: 119 RIRTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFL 178
           RI     K  DWEVEL +V+G     V E DAL HVAGY +A D+S R +Q E+  GQ+ 
Sbjct: 113 RIPPGALK-TDWEVELGIVIGTRMQQVAEADALAHVAGYVLANDVSERSYQMERG-GQWD 170

Query: 179 LGKSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSV 238
            GK  DTF P+GP ++T+DE+     + +   +NG   Q   T   +  +P +L  IS  
Sbjct: 171 KGKGCDTFAPVGPWLVTTDEIPDPHAIGLWLEVNGQRMQDGHTRNFIFGVPRVLAYISQF 230

Query: 239 MTLVPGDLILTGTPGGVGMYRQP-PEYLQPGDVL 271
           MTL PGDL+LTGTP GVG+ ++P P +L+ GDV+
Sbjct: 231 MTLEPGDLVLTGTPAGVGLGQKPTPRFLRAGDVM 264


>UniRef50_Q1GLV2 Cluster: 5-carboxymethyl-2-hydroxymuconate
           delta-isomerase; n=4; Bacteria|Rep:
           5-carboxymethyl-2-hydroxymuconate delta-isomerase -
           Silicibacter sp. (strain TM1040)
          Length = 281

 Score =  185 bits (450), Expect = 1e-45
 Identities = 99/229 (43%), Positives = 140/229 (61%), Gaps = 6/229 (2%)

Query: 54  LKSTKPATIPLSSVT--LTAPIHGVDKILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTI 111
           L++  P ++PL   T  + A +  V K +CIGLNY DH  E  ++ P  P++F K +S I
Sbjct: 46  LRALDPQSLPLVEGTPRIGACVGQVGKFICIGLNYADHAAESGMSLPEEPVIFFKATSAI 105

Query: 112 IGPDQPVRI-RTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQK 170
            GP+  V I RT V  K DWEVEL VV+G+ A  +  ++AL HVAGY V  D+S RD+Q 
Sbjct: 106 CGPNDAVEIPRTSV--KTDWEVELGVVIGKTAKYIGRDEALDHVAGYCVVNDLSERDFQL 163

Query: 171 EKNMGQFLLGKSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPS 230
            ++ GQ++ GKS DTF P+GP ++T DEV     L +   +NG   Q  ST  +   + +
Sbjct: 164 HRS-GQWVKGKSADTFGPIGPWLVTRDEVPDPQNLAMWLEVNGHRYQDGSTRTMHFDVAT 222

Query: 231 LLHRISSVMTLVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIG 279
           ++  +S  M+L PGD+I TGTP GVGM + P  YL+PGDV+   I  +G
Sbjct: 223 VISHLSQFMSLQPGDVISTGTPPGVGMGQTPETYLKPGDVMELGIAGLG 271


>UniRef50_Q5LLB0 Cluster: Fumarylacetoacetate hydrolase family
           protein; n=8; Proteobacteria|Rep: Fumarylacetoacetate
           hydrolase family protein - Silicibacter pomeroyi
          Length = 305

 Score =  184 bits (449), Expect = 2e-45
 Identities = 111/299 (37%), Positives = 171/299 (57%), Gaps = 25/299 (8%)

Query: 1   MKLVQFSYKDSPKNI-RVGYLEGDDIVDIN----KADSSLPTTLLQILRNGD------LE 49
           MKLV  +Y+DS     R+G +    +VD+      A  +LP ++L ++  G         
Sbjct: 1   MKLV--TYRDSAAGEGRLGVVVDGQVVDVEWLGEAAGEALPDSMLDLIDMGPDALAAITR 58

Query: 50  KVKKLKSTKPA--TIPLSSVTLTAPIHGVDK-ILCIGLNYKDHCQEQ------NLTPPPV 100
            +    + +PA   +P  +V L API    K I  IGLNY +H  E       +   P  
Sbjct: 59  ALDATNAARPAGLAVPEENVRLLAPIPRPRKNIFGIGLNYVEHVAESAKSLDTSKELPKE 118

Query: 101 PMVFSKFSSTIIGPDQPVRIRTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVA 160
           P+VFSK  +++I   + ++    +T+++DWEVEL V++G+ A+ + +++A+ HV GY+V 
Sbjct: 119 PVVFSKPPTSVIASGEGIQHNAAMTQQLDWEVELAVIIGKRATRIAKDNAMSHVFGYSVI 178

Query: 161 QDISARDWQKEKNMGQFLLGKSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSS 220
            D+SARD    +  GQ++  K  DTFCP GP ++T+D+V     L +  + NGV KQ S+
Sbjct: 179 NDVSARD---NRRAGQWIFSKGQDTFCPFGPAIITADDVPDPHNLDLWLTKNGVEKQRSN 235

Query: 221 TAQLVHSIPSLLHRISSVMTLVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIG 279
           T  L+  IP+L+  ISS +TL PGD+I TGTP GVG  R P E++ PGDV+   ++ IG
Sbjct: 236 TRHLLFDIPTLIADISSGITLEPGDIIATGTPAGVGAGRDPQEWMWPGDVIECGVDGIG 294


>UniRef50_Q1VM36 Cluster: 2-keto-4-pentenoate
           hydratase/2-oxohepta-3-ene-1 7-dioic acid hydratase;
           n=1; Psychroflexus torquis ATCC 700755|Rep:
           2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1 7-dioic
           acid hydratase - Psychroflexus torquis ATCC 700755
          Length = 251

 Score =  184 bits (449), Expect = 2e-45
 Identities = 91/211 (43%), Positives = 137/211 (64%), Gaps = 4/211 (1%)

Query: 48  LEKVKKLKSTKPATIPL--SSVTLTAPIHGVDKILCIGLNYKDHCQEQNLTPPPVPMVFS 105
           ++++ +  ST  +  P+    + L +PI    KI+C+GLNY  H +E  +  P  P++F 
Sbjct: 43  IKRLAEWLSTNKSNCPIIGKEIRLGSPIDRPSKIVCVGLNYAKHAKESGMEVPTEPVLFF 102

Query: 106 KFSSTIIGPDQPVRIRTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISA 165
           K SS I+GP   + I    ++K DWEVEL +++G +AS V+E +A+ HVAGY +  DIS 
Sbjct: 103 KASSAIVGPYDDI-ILPKKSEKSDWEVELAIIIGDKASYVKESEAMDHVAGYVIHNDISE 161

Query: 166 RDWQKEKNMGQFLLGKSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLV 225
           R++Q E++ GQ++ GKS DTF P+GP ++T+DE+     LR+   LNG   Q S+T+ L+
Sbjct: 162 REYQLERS-GQWVKGKSCDTFAPIGPFMVTTDEIDDPHNLRLWLKLNGETMQDSNTSDLI 220

Query: 226 HSIPSLLHRISSVMTLVPGDLILTGTPGGVG 256
             IP L+  IS+ MTL+PGD+I TGTP GVG
Sbjct: 221 FGIPKLVSYISTYMTLLPGDVISTGTPFGVG 251


>UniRef50_A0KDR8 Cluster: 5-carboxymethyl-2-hydroxymuconate
           delta-isomerase; n=6; Burkholderiales|Rep:
           5-carboxymethyl-2-hydroxymuconate delta-isomerase -
           Burkholderia cenocepacia (strain HI2424)
          Length = 293

 Score =  184 bits (449), Expect = 2e-45
 Identities = 102/257 (39%), Positives = 156/257 (60%), Gaps = 22/257 (8%)

Query: 45  NGDL-EKVKKLKSTKPATIP------LSSVTLTAPIHGVDK-ILCIGLNYKDHCQE-QNL 95
           +GD+ + V++ +  KP   P      L+  T+ API    + I C+G NY +H  E QN 
Sbjct: 35  DGDMVQLVQQFEEVKPHLKPTGNGLSLAEATILAPIDQPRRNIFCVGKNYHEHAAEFQNS 94

Query: 96  T----------PPPVPMVFSKFSSTIIGPDQPVRIRTDVTKKVDWEVELCVVVGREASCV 145
                       P  P++F+K +ST+IGP   +     VT ++D+E EL VV+G+    +
Sbjct: 95  GFDSSAKNGEHAPEAPVIFTKPASTVIGPSAKIPRHVGVTAQLDYEAELGVVIGKGGRGI 154

Query: 146 REEDALQHVAGYTVAQDISARDWQKEKNMGQFLLGKSMDTFCPLGPCVLTSDEVGAAVEL 205
           ++ DA+ +V GYTV  D +ARD QK     Q+ LGKS+D FCP+GP V+TSDEV     +
Sbjct: 155 KKADAMNYVFGYTVINDFTARDLQKLHR--QWFLGKSLDGFCPMGPFVITSDEVNGQ-NI 211

Query: 206 RVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPGDLILTGTPGGVGMYRQPPEYL 265
            + C +NG L+Q+S+T++L+  IP+L+  +S+ + L PGD+I TGTP GVG+   PP++L
Sbjct: 212 DIKCWVNGELRQNSNTSKLIFDIPTLIETLSAGIELQPGDVIATGTPAGVGIGFNPPKFL 271

Query: 266 QPGDVLTSEIEKIGAFD 282
           Q GDV+  EI+ +G  +
Sbjct: 272 QKGDVIRIEIQNVGVLE 288


>UniRef50_Q12CU6 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate
           decarboxylase; n=2; Proteobacteria|Rep:
           5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase -
           Polaromonas sp. (strain JS666 / ATCC BAA-500)
          Length = 287

 Score =  184 bits (448), Expect = 2e-45
 Identities = 106/293 (36%), Positives = 166/293 (56%), Gaps = 17/293 (5%)

Query: 1   MKLVQFSYKDSPKNIRVGYLEGDDIVDINKADSSLPTTLLQILRNGDLEKVKKLKSTKPA 60
           M++  + + +  +++ V   +G  +  +N A     T  L ++  GD +K+  L+S    
Sbjct: 1   MRIATYQW-NGQRHVGVVSEDGRSLTPVNLAPGQADTGALAVIALGDPKKLP-LRSE--- 55

Query: 61  TIPLSSVTLTAPIHGVDK-ILCIGLNYKDHCQE--------QNLTPPPVPMVFSKFSSTI 111
           ++ L  V L API    + I C+G NY  H +E         +  P   P+VF+K    +
Sbjct: 56  SVSLHDVKLEAPIPLPRRNIFCVGRNYHAHAKELSASVFKDNSANPASWPIVFTKVPECV 115

Query: 112 IGPDQPVRIRTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKE 171
           +GP   V + T V++++D+E EL +V+G     +    A+QHV GYT+  D++ARD Q  
Sbjct: 116 VGPTDDVMLPTGVSEEIDYESELAIVIGTGGRNISRAAAMQHVFGYTIINDVTARDVQMR 175

Query: 172 KNMGQFLLGKSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSL 231
               Q+ LGKS DTFCP+GP ++T+DE+  +   RV   +NG L+Q + T  L+  IP+L
Sbjct: 176 HQ--QWDLGKSFDTFCPMGPWIVTADELDGS-RTRVRGWVNGELRQDAQTTDLIFDIPAL 232

Query: 232 LHRISSVMTLVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIGAFDVR 284
           +   S  +TL PGD+I TGT  GVGM  +PP+YL+ GDV+  EI+ IGA + R
Sbjct: 233 IETCSRGITLYPGDVIATGTAAGVGMGMKPPQYLKAGDVVRIEIDGIGAIENR 285


>UniRef50_Q7W6X4 Cluster: Putative uncharacterized protein; n=2;
           Bordetella|Rep: Putative uncharacterized protein -
           Bordetella parapertussis
          Length = 294

 Score =  183 bits (446), Expect = 4e-45
 Identities = 103/295 (34%), Positives = 164/295 (55%), Gaps = 18/295 (6%)

Query: 1   MKLVQFSYKDSPKNIRVGYLEGDD-IVDINKADSSLPTTLLQILRNGDLE-KVKKLKSTK 58
           MK + F   D  ++   G + G D +VD+  A   LP  L  + R+G L   V +L +  
Sbjct: 1   MKYISFELPDGRRH--AGVMTGPDTLVDLTDA-MDLPDLLTLLQRHGQLAGDVARLAAQA 57

Query: 59  PATIPLSSVTLTAPIHGVDK-ILCIGLNYKDHCQEQNLTP----------PPVPMVFSKF 107
             T+ L +V + AP+    + + C+G NY +H +E   +           P  P++FSK 
Sbjct: 58  RHTVALDAVRVLAPLPNPPRNVFCVGKNYHEHAREFARSGFDSSAAAGAVPAAPIIFSKP 117

Query: 108 SSTIIGPDQPVRIRTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARD 167
            S++ GP   +    D    VD+E EL VV+G+      ++D    V GYT+  D+++R 
Sbjct: 118 PSSVSGPGDAIDTALDPCDSVDYEAELAVVIGKAGRVAPDDDPWSFVFGYTLVNDVTSRG 177

Query: 168 WQKEKNMGQFLLGKSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHS 227
            QK  +  Q+LLGK +D +CP+GP ++++DE+G    L ++C +NG L+QS+  + L+  
Sbjct: 178 LQKRHS--QWLLGKGIDGYCPMGPALVSADEIGDIGALEITCEVNGELRQSARLSDLIFD 235

Query: 228 IPSLLHRISSVMTLVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIGAFD 282
           IP+L+  I + +TL PGD+I TGTP GVG+   PP+YL+ GDV+    E IG  +
Sbjct: 236 IPTLVRAIGASITLQPGDVIATGTPVGVGIGFTPPKYLRRGDVVRVRAEPIGVLE 290


>UniRef50_A5MZU4 Cluster: Putative uncharacterized protein; n=1;
           Clostridium kluyveri DSM 555|Rep: Putative
           uncharacterized protein - Clostridium kluyveri DSM 555
          Length = 301

 Score =  183 bits (446), Expect = 4e-45
 Identities = 104/296 (35%), Positives = 169/296 (57%), Gaps = 21/296 (7%)

Query: 1   MKLVQFSYKDSPKNIRVGYLEGDDIVDINK-----ADSSLPTTLLQILRNGDLEKVKK-- 53
           MK V + YK       +G L+   I++         + + P  ++++++  D +K+ +  
Sbjct: 1   MKFVTYDYKGKEN---IGILKDKSILNFESIFYEIGEENPPKDMVELIKYLDEDKLNEVE 57

Query: 54  --LKSTKPATIPLSSVTLTAPI-HGVDKILCIGLNYKDHCQEQNLTP------PPVPMVF 104
             LKS     + L +V L API +    + C+G NY++H +E  LT       P VP+ F
Sbjct: 58  EFLKSKSLQGVFLDTVKLKAPIPYPKRNVFCLGKNYEEHAREIKLTRITGNEIPKVPIYF 117

Query: 105 SKFSSTIIGPDQPVRIRTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDIS 164
           +K +S  IG    +   ++VT +VD+EVEL VV+G+    +++E+A +++ GYT+  DIS
Sbjct: 118 TKVASPAIGNGDSIEFSSEVTNQVDYEVELGVVIGKNGKNIKKEEAEKYIFGYTIINDIS 177

Query: 165 ARDWQKEKNMGQFLLGKSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQL 224
           ARD Q      Q+  GKS+DTFCP+GPC++  +E+   + L + C +N  L+Q S+T  L
Sbjct: 178 ARDLQGSHI--QWFKGKSLDTFCPMGPCIVHKNEIPFPINLDIKCWVNEELRQDSNTKNL 235

Query: 225 VHSIPSLLHRISSVMTLVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIGA 280
           +  IP ++  +S  ++L  GD+I TGTP GVGM   P + L+ GD +   IEKIG+
Sbjct: 236 IFDIPYIISDLSKGVSLKAGDIIATGTPSGVGMGFSPIKVLKQGDSIECYIEKIGS 291


>UniRef50_Q5WIZ5 Cluster: 2-keto-4-pentenoate
           hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase;
           n=1; Bacillus clausii KSM-K16|Rep: 2-keto-4-pentenoate
           hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase -
           Bacillus clausii (strain KSM-K16)
          Length = 292

 Score =  181 bits (441), Expect = 2e-44
 Identities = 91/231 (39%), Positives = 141/231 (61%), Gaps = 5/231 (2%)

Query: 51  VKKLKSTKPATIPLSSVTLTAPIHGVDKILCIGLNYKDHCQEQNLTPPPVPMVFSKFSST 110
           ++ L+ T P    + S T    I   +KI+CIGLNY+ H  E     P  P++FSKF++T
Sbjct: 55  MQTLEQTGPYMHAIESCTFGPAIPNPEKIICIGLNYRRHADETGSPYPETPILFSKFNNT 114

Query: 111 IIGPDQPVRIRTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQK 170
           + G    + +   VT+ +D+EVEL +V+G+ A  V E++AL +V GY  A D+SARD Q 
Sbjct: 115 LTGHGSNIVV-PPVTQALDYEVELAIVIGKTAKQVTEDEALNYVLGYCTANDLSARDLQM 173

Query: 171 EKNMGQFLLGKSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPS 230
           +    Q+LLGK+ D FCP+GP ++T +++     L +   +NG +KQ S+TA ++ +   
Sbjct: 174 KT--AQWLLGKTCDGFCPIGPFLVTKEDIADPQNLALETRVNGEIKQQSNTADMIFTCAE 231

Query: 231 LLHRISSVMTLVPGDLILTGTPGGV--GMYRQPPEYLQPGDVLTSEIEKIG 279
           ++  +S   TL PGD++LTGTP GV  G+      YLQPGD ++  IE++G
Sbjct: 232 IISYVSRHFTLKPGDILLTGTPEGVILGLPEAERRYLQPGDTVSVHIEQLG 282


>UniRef50_A4FCY5 Cluster: 5-carboxymethyl-2-hydroxymuconate
           delta-isomerase; n=1; Saccharopolyspora erythraea NRRL
           2338|Rep: 5-carboxymethyl-2-hydroxymuconate
           delta-isomerase - Saccharopolyspora erythraea (strain
           NRRL 23338)
          Length = 233

 Score =  181 bits (441), Expect = 2e-44
 Identities = 95/201 (47%), Positives = 121/201 (60%), Gaps = 2/201 (0%)

Query: 79  ILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRIRTDVTKKVDWEVELCVVV 138
           I  + LNY D   E     P VP +F K SS++IG   P+ + T VT+ VDWE EL VV+
Sbjct: 16  IFGVALNYVDSIAEMGFERPTVPFLFPKLSSSVIGDGDPIVVDTTVTRFVDWETELAVVI 75

Query: 139 GREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLLGKSMDTFCPLGPCVLTSDE 198
           G EA  V   +AL+ V GYTVA DISARD       GQ+L GK +DTFCPLG  V+ + E
Sbjct: 76  GTEARNVPAAEALEVVYGYTVANDISARDLLTAD--GQWLRGKGLDTFCPLGHVVVPAAE 133

Query: 199 VGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPGDLILTGTPGGVGMY 258
           +     L V   LNG + Q  +TA +V  +  L+  +S   TL PGD+ILTGTP G G +
Sbjct: 134 IPDPQALAVRTWLNGEIVQDGTTADMVFGVGELISYLSRFFTLRPGDVILTGTPAGCGAF 193

Query: 259 RQPPEYLQPGDVLTSEIEKIG 279
             PP  L+PGDV+ SE+E IG
Sbjct: 194 MDPPRGLRPGDVVESEVEGIG 214


>UniRef50_Q6I239 Cluster: Fumarylacetoacetate hydrolase family
           protein; n=21; Firmicutes|Rep: Fumarylacetoacetate
           hydrolase family protein - Bacillus anthracis
          Length = 302

 Score =  180 bits (439), Expect = 3e-44
 Identities = 96/256 (37%), Positives = 150/256 (58%), Gaps = 12/256 (4%)

Query: 34  SLPTTLLQILRNGD--LEKVKKL-----KSTKPATIPLSSVTLTAPIHGVDK-ILCIGLN 85
           ++P T+L+ +  G    EK+  +     ++   A  PL+ V + API    K ILC+G N
Sbjct: 42  TIPITMLECIERGTECFEKICDIVNWAKENGGTAYYPLTEVKILAPIPRPRKNILCVGKN 101

Query: 86  YKDHCQEQNLTP--PPVPMVFSKFSSTIIGPDQPVRIRTDVTKKVDWEVELCVVVGREAS 143
           Y++H  E       P   M+F+K  +T+IG D+ +      T ++D+E EL +V+G+   
Sbjct: 102 YREHAIEMGGVESIPENIMIFTKAPTTVIGMDEKINSHPHATNELDYEGELAIVIGKRGK 161

Query: 144 CVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLLGKSMDTFCPLGPCVLTSDEVGAAV 203
            +++E AL+HV GYT+  DI+ARD Q++    QF LGKS DTFCP+GP ++    +    
Sbjct: 162 QIKKEKALEHVFGYTIINDITARDIQRKHK--QFFLGKSFDTFCPMGPYLIHKSMISTPN 219

Query: 204 ELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPGDLILTGTPGGVGMYRQPPE 263
            L +   +NG ++Q+S+T +++ SI  ++  IS  MTL PGD+I TGTP GVG    PP+
Sbjct: 220 ALHIETIVNGEVRQTSNTNKMIFSIEEIISTISKGMTLEPGDIIATGTPAGVGKGFTPPK 279

Query: 264 YLQPGDVLTSEIEKIG 279
           +L  GD +   +E IG
Sbjct: 280 FLHAGDEVVITVEGIG 295


>UniRef50_A4V8P0 Cluster: Putative fumarylacetoacetate hydrolase
           family protein; n=2; Arthrobacter|Rep: Putative
           fumarylacetoacetate hydrolase family protein -
           Arthrobacter nitroguajacolicus
          Length = 299

 Score =  180 bits (439), Expect = 3e-44
 Identities = 102/247 (41%), Positives = 138/247 (55%), Gaps = 9/247 (3%)

Query: 42  ILRNGDLEKVKKLKSTKPA-TIPL--SSVTLTAPIHGVDKILCIGLNYKDHCQEQNLTPP 98
           ++ NG  E  +   S + A  +PL  +   L   +    K++C GLNY DH QE     P
Sbjct: 36  LMDNGWREVAEDAASGRKAGAVPLHGAQADLAPLLPAAAKVICCGLNYGDHIQEMGRALP 95

Query: 99  PVPMVFSKFSSTIIGPDQPVRIRTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYT 158
             P +F+K++ T++G   P+ +    + KVDWE EL VV+G     V E+ AL  +AGYT
Sbjct: 96  DYPTLFAKYADTLVGASDPIYVHG--SDKVDWEAELAVVIGSNLYRVDEDQALAGIAGYT 153

Query: 159 VAQDISARDWQKEKNMGQFLLGKSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQS 218
           VA D+S RDWQ      Q+  GK+ D   PLGP +LT+DE  A  +  V   +NG   Q 
Sbjct: 154 VANDVSMRDWQNRTL--QWFQGKAFDATTPLGPVMLTADE--APADFDVYGYVNGEQVQK 209

Query: 219 SSTAQLVHSIPSLLHRISSVMTLVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKI 278
            +T+ LV     L+  IS    L PGD++LTGTPGGVGM   PP +L  GDVLT+EI  I
Sbjct: 210 GNTSTLVFGPARLVAYISQFTMLRPGDVVLTGTPGGVGMGMNPPRFLSDGDVLTTEIPGI 269

Query: 279 GAFDVRI 285
           G  + RI
Sbjct: 270 GRLENRI 276


>UniRef50_Q7WM06 Cluster: Putative oxygenase; n=3; Bordetella|Rep:
           Putative oxygenase - Bordetella bronchiseptica
           (Alcaligenes bronchisepticus)
          Length = 287

 Score =  180 bits (438), Expect = 4e-44
 Identities = 99/263 (37%), Positives = 146/263 (55%), Gaps = 6/263 (2%)

Query: 18  GYLEGDDIVDINKADSSLPTTLLQILRNGDLEKVKKLKSTKPAT-IPLSSVTLTAPIHGV 76
           G + G+ I+D+  A    PT    + R+G      +L+    A  + L+  TL API   
Sbjct: 19  GAVVGERIIDL--ATPQAPTLRAALARDGVDGLAARLRQADGAAGLALADATLLAPITDP 76

Query: 77  DKILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRIRTDVTKKVDWEVELCV 136
           DKILCIGLNY+ H +E  +  P  P  F +F+ ++    QPV +R   + + D+E EL V
Sbjct: 77  DKILCIGLNYRLHAEEAGMAIPARPSTFVRFAGSLAAQGQPV-LRPAESDQFDYEAELAV 135

Query: 137 VVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLLGKSMDTFCPLGPCVLTS 196
           ++G+ A  V +  A++HVAGY    + S RDWQ+     Q   GK+       GP ++T+
Sbjct: 136 IIGKPARRVSQARAMEHVAGYACLAENSVRDWQRHST--QATPGKNFVRSGAFGPWLVTA 193

Query: 197 DEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPGDLILTGTPGGVG 256
           DE GA   + V   LNG   Q  S A ++ ++  L+  +S+   L+PGD+I TGTP GVG
Sbjct: 194 DEAGAPEAMTVIGRLNGETVQHDSVANMIFTVAQLVSYLSTFAELLPGDVIATGTPAGVG 253

Query: 257 MYRQPPEYLQPGDVLTSEIEKIG 279
           M R+PP YL+PGDV   +I  +G
Sbjct: 254 MSRKPPRYLRPGDVFEVDISGVG 276


>UniRef50_Q67K64 Cluster: Putative
           2-hydroxyhepta-2,4-diene-1,7-dioate isomerase; n=1;
           Symbiobacterium thermophilum|Rep: Putative
           2-hydroxyhepta-2,4-diene-1,7-dioate isomerase -
           Symbiobacterium thermophilum
          Length = 254

 Score =  180 bits (438), Expect = 4e-44
 Identities = 98/219 (44%), Positives = 128/219 (58%), Gaps = 11/219 (5%)

Query: 61  TIPLSSVTLTAPIHGVDKILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRI 120
           T+PL +V L AP+    KI+CIG NY+DH  E     P  PM F K  S +IGP + +R+
Sbjct: 40  TVPLQAVQLLAPVTP-SKIVCIGRNYRDHAAELGNAAPERPMFFLKAPSALIGPGEAIRL 98

Query: 121 RTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLLG 180
             D    V WE EL VV+GR    V   DAL +V GYT+A D+S RD QK      F  G
Sbjct: 99  -PDPDATVHWEAELAVVIGRRMKDVAPADALSYVFGYTIANDVSHRDAQKADGAFGFGRG 157

Query: 181 KSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMT 240
           KS DTFCP GP V+T     A   + ++C  N  ++QS ST  ++H +P LL  +S +MT
Sbjct: 158 KSYDTFCPCGPAVVTEGIDPADALITLTC--NEEVRQSDSTGLMIHPVPELLSYLSQIMT 215

Query: 241 LVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIG 279
           L+PGDL+LTGTP GVG        ++PGD++   I  IG
Sbjct: 216 LMPGDLVLTGTPKGVGA-------MKPGDLIEIHIPGIG 247


>UniRef50_Q2BPP6 Cluster: 5-carboxymethyl-2-hydroxymuconate
           delta-isomerase; n=3; Bacteria|Rep:
           5-carboxymethyl-2-hydroxymuconate delta-isomerase -
           Neptuniibacter caesariensis
          Length = 286

 Score =  180 bits (437), Expect = 5e-44
 Identities = 93/218 (42%), Positives = 135/218 (61%), Gaps = 4/218 (1%)

Query: 62  IPLSSVTLTAPIHGVDKILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRIR 121
           IPL+ V+L AP+    K L +GLNY DH +E  L  P  P  F+K SS +IGP++ +  R
Sbjct: 58  IPLNEVSLLAPVASPQKFLGVGLNYADHIEETGLDTPEFPTFFNKQSSCVIGPNEAIH-R 116

Query: 122 TDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLLGK 181
             V++K+D+E EL +V+G+    V  E A + +AG+T+  D+S RDWQ +     + LGK
Sbjct: 117 PTVSEKLDYEGELAIVIGKACRHVPYEKASEVIAGFTIVNDVSVRDWQIKSPT--WTLGK 174

Query: 182 SMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTL 241
           S DT  P+GP ++T+DEV     L +   +N  L+Q S+T  L+     L+  +S+V TL
Sbjct: 175 SFDTHGPMGPWIVTADEVNPH-NLELKTWVNDELRQHSNTKHLIFDCYQLIETLSTVCTL 233

Query: 242 VPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIG 279
            PGD+I TGT  GVG+  +P  Y++PGD +T EIE IG
Sbjct: 234 QPGDVIATGTSSGVGVKMKPRGYMKPGDRVTIEIEGIG 271


>UniRef50_A6TKL2 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=3;
           Clostridiaceae|Rep: Fumarylacetoacetate (FAA) hydrolase
           - Alkaliphilus metalliredigens QYMF
          Length = 300

 Score =  178 bits (433), Expect = 2e-43
 Identities = 99/303 (32%), Positives = 175/303 (57%), Gaps = 20/303 (6%)

Query: 1   MKLVQFSYKDSPKNIRVGYLEGDD--IVDINKADSSL----PTTLLQILRNGDLEKVKKL 54
           MK + F+ KD  +N R+G  +  +  ++D+N    S        L++ ++  D++ +K++
Sbjct: 1   MKFIAFTTKDK-ENTRLGVYKNSESIVIDLNTIGLSRFFHDMNDLIKNIKPKDIDVLKEV 59

Query: 55  KST----KPATIPLSSVTLTAPI-HGVDKILCIGLNYKDHCQE------QNLTPPPVPMV 103
            S     +  T  +  +TL API   +  ++C+GLNY +H  E      +N+  P   + 
Sbjct: 60  ISLVEEKEYETYHVEEITLGAPIDRTIHDVICVGLNYAEHIDETKKGFDENMEIPLHTVY 119

Query: 104 FSKFSSTIIGPDQPVRIRTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDI 163
           FSK ++ + GP + +   + + + +D+EVEL V++G+E   + +E+A +++ GYT+  D+
Sbjct: 120 FSKRANQVKGPGEEIESHSHLNESMDYEVELAVIIGKEGINISKEEAKEYIFGYTILNDL 179

Query: 164 SARDWQKEKNMGQFLLGKSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQ 223
           SAR  QK  N  Q+  GKS+D F  +GPC++    VG  +EL +   +N  L+Q+S+T  
Sbjct: 180 SARGLQK--NHVQWFRGKSLDGFTSMGPCIVHGSSVGFPLELDIKSRVNDELRQNSNTKF 237

Query: 224 LVHSIPSLLHRISSVMTLVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIGAFDV 283
           ++  + +++  IS  MTL+PGD+I TGTP GVGM   PP +L+ GD +  EI+ +G    
Sbjct: 238 MMKDVSTIISEISQGMTLLPGDVIATGTPSGVGMGFTPPRFLKAGDTVECEIQHMGLLKN 297

Query: 284 RIE 286
           +I+
Sbjct: 298 KIK 300


>UniRef50_Q1YHR9 Cluster: Putative fumarylacetoacetate hydrolase;
           n=1; Aurantimonas sp. SI85-9A1|Rep: Putative
           fumarylacetoacetate hydrolase - Aurantimonas sp.
           SI85-9A1
          Length = 293

 Score =  177 bits (431), Expect = 3e-43
 Identities = 105/296 (35%), Positives = 168/296 (56%), Gaps = 22/296 (7%)

Query: 1   MKLVQFSYKDSPKNIRVGYLEGDDIVDINKADSSLPTTLLQILRNGDLEKVKKLKSTKPA 60
           MKL+ F     P     G L+G++IV      ++     ++ +  GD E +   K TK A
Sbjct: 1   MKLLTFERDGVPG---AGLLDGNEIVVCETGAAA--RLAVRRIAEGDAELLDAWK-TKAA 54

Query: 61  T----IPLSSVTLTAPIHGVDK-ILCIGLNYKDHCQEQNLTP---------PPVPMVFSK 106
                +  S VT+ AP+    + I C+G NY++H  E + +          P  P++F+K
Sbjct: 55  NGAERLSRSEVTILAPLPETRRDIFCVGKNYREHASEFHNSGFDSGGKQAIPVAPVIFTK 114

Query: 107 FSSTIIGPDQPVRIRTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISAR 166
             S IIGP   +    D T+ VD+E EL VV+G+ A  V + DA+ +V GY V  D+++R
Sbjct: 115 SLSAIIGPGATIEAGLDRTRTVDYEGELGVVIGKRAFGVTKADAMDYVFGYVVINDVTSR 174

Query: 167 DWQKEKNMGQFLLGKSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVH 226
           + Q+  +  Q+++GK +DTF P+GP ++T+DEV    +L V+ ++NG  +Q +S A L+ 
Sbjct: 175 ELQRHHS--QWVIGKGIDTFAPMGPVLVTADEVPDVTKLTVTTTVNGETRQKASVAGLIF 232

Query: 227 SIPSLLHRISSVMTLVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIGAFD 282
            IP+L+  +++ MTL+PGD+I TGTP GVG+   PP YL  GD +   I+ +G  +
Sbjct: 233 DIPTLIETMTATMTLLPGDIIATGTPAGVGIGFDPPRYLADGDRVAVTIDGLGTLE 288


>UniRef50_A6TL34 Cluster: 5-carboxymethyl-2-hydroxymuconate
           Delta-isomerase; n=1; Alkaliphilus metalliredigens
           QYMF|Rep: 5-carboxymethyl-2-hydroxymuconate
           Delta-isomerase - Alkaliphilus metalliredigens QYMF
          Length = 298

 Score =  177 bits (431), Expect = 3e-43
 Identities = 90/244 (36%), Positives = 142/244 (58%), Gaps = 9/244 (3%)

Query: 43  LRNGDLEKVKKLKSTKPATIPLSSVTLTAPIHGVDK-ILCIGLNYKDHCQEQN------L 95
           LR    E +   K  +     +  V + API  + + ++C+GLNYK H  E        +
Sbjct: 50  LREVAKEVIDNKKLWQEQGTDIYKVKVIAPIPRLKRNVICLGLNYKAHVAESQSALSAGI 109

Query: 96  TPPPVPMVFSKFSSTIIGPDQPVRIRTDVTKKVDWEVELCVVVGREASCVREEDALQHVA 155
             P  P+ F+K S+  IGP + +     +T++VD+EVEL V++G+  + +  E+   H+ 
Sbjct: 110 KMPEFPVYFTKMSTQAIGPQEAINSHPQITQEVDYEVELAVIIGKGGTNIPPEEVQDHIF 169

Query: 156 GYTVAQDISARDWQKEKNMGQFLLGKSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVL 215
           GYT+  D+SARD Q+  N  Q++ GKS+DTF  +GP ++  + +   VEL +   +NG +
Sbjct: 170 GYTILNDVSARDLQRRHN--QWVKGKSLDTFTVMGPWIMEKETISLPVELDLYSKVNGEI 227

Query: 216 KQSSSTAQLVHSIPSLLHRISSVMTLVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEI 275
           +Q S+T   +  IP+++  +S  +TL  GD+I TGTP GVGM   PP+YL+ GDV+   I
Sbjct: 228 RQHSNTKDFIFDIPTVISELSKGLTLEAGDVIATGTPAGVGMGFNPPKYLKAGDVVECYI 287

Query: 276 EKIG 279
           EKIG
Sbjct: 288 EKIG 291


>UniRef50_Q89JJ8 Cluster: Blr5285 protein; n=7; Proteobacteria|Rep:
           Blr5285 protein - Bradyrhizobium japonicum
          Length = 283

 Score =  177 bits (430), Expect = 4e-43
 Identities = 101/279 (36%), Positives = 157/279 (56%), Gaps = 7/279 (2%)

Query: 1   MKLVQFSYKDSPKNIRVGYLEGDDIVDINKADSSLPTTLLQILRNGDLEKVKKLKSTKPA 60
           MKL+ F   DS  +   G ++ + +VD+    +   TTL Q+L  G + +  KL ++   
Sbjct: 1   MKLLSFIV-DSRTSF--GAVKDNGVVDLGARMAGC-TTLRQLLEAGRVAEAAKLVASAAP 56

Query: 61  TIPLSSVTLTAPIHGVDKILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRI 120
              L  V+    I    KI+C+GLNY+DH  E        P +F +F  + +G  QP+ +
Sbjct: 57  DHALDKVSFAPVIPDPGKIICVGLNYRDHVAETGRIVTEKPALFVRFPCSQVGHLQPI-V 115

Query: 121 RTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLLG 180
           +  V+   D+E EL +V+G+E   +    AL H+AGY+   + S RDWQ+  +  QFL G
Sbjct: 116 KPKVSDDFDYEGELALVIGKEGRHIPANRALDHIAGYSCYNEGSVRDWQRHTS--QFLSG 173

Query: 181 KSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMT 240
           K+       GP ++T+DE+    +L +   LNG + Q ++T  L+ +IP L+  IS++  
Sbjct: 174 KTFAESGSFGPWLVTADEIPDPSKLTLQTRLNGTVVQDTTTDLLITAIPGLIAYISTICP 233

Query: 241 LVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIG 279
           LVPGD+I+TGTPGGVG  R PP +++PGD +  EI  IG
Sbjct: 234 LVPGDVIVTGTPGGVGAKRTPPLWMRPGDTVEVEISGIG 272


>UniRef50_Q67SA7 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate
           isomerase; n=1; Symbiobacterium thermophilum|Rep:
           2-hydroxyhepta-2,4-diene-1,7-dioate isomerase -
           Symbiobacterium thermophilum
          Length = 294

 Score =  176 bits (429), Expect = 5e-43
 Identities = 90/224 (40%), Positives = 134/224 (59%), Gaps = 3/224 (1%)

Query: 62  IPLSSVTLTAPIHGVDKILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRIR 121
           +P   + L  P+    KILC+GLNY+ H  E ++  P  P++F+KF + + GP  PV + 
Sbjct: 70  LPEDGLRLGPPVPRPGKILCVGLNYRAHAAEAHMAVPAYPVLFAKFQNAVAGPGDPV-VL 128

Query: 122 TDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLLGK 181
             + ++ D+E EL VV+GR A  V  E AL +V GY    D+SAR+ Q   +  Q+LLGK
Sbjct: 129 PSIAEQYDYEAELVVVIGRRARRVPAEAALDYVLGYCNGNDLSARELQMRTS--QWLLGK 186

Query: 182 SMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTL 241
           S+D F P+GP ++T DEV    +LR+    NG ++Q   T  ++  +  L+  IS  MTL
Sbjct: 187 SLDGFLPIGPYLVTRDEVPDPQDLRIRLWRNGEIRQDGHTRNMLFPVAELIAYISRYMTL 246

Query: 242 VPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIGAFDVRI 285
            PGD+I TGTP GV M     ++L+PGDV+  EI+ +G  + R+
Sbjct: 247 EPGDIIATGTPEGVIMGLAEKDWLKPGDVVAVEIDGLGRLENRL 290


>UniRef50_A0VVP4 Cluster: 5-carboxymethyl-2-hydroxymuconate
           delta-isomerase; n=5; Bacteria|Rep:
           5-carboxymethyl-2-hydroxymuconate delta-isomerase -
           Dinoroseobacter shibae DFL 12
          Length = 308

 Score =  175 bits (426), Expect = 1e-42
 Identities = 94/231 (40%), Positives = 142/231 (61%), Gaps = 9/231 (3%)

Query: 56  STKPATIPLSSVTLTAPIHGVDK-ILCIGLNYKDHCQE----QN--LTPPPVPMVFSKFS 108
           S + A I L +  L AP+H   K I C+G NY +H  E    QN  +     P+ F+K +
Sbjct: 71  SYRDARISLDNPFL-APLHTPRKNIFCVGRNYAEHIAEGERAQNAKIGITEHPVYFTKPA 129

Query: 109 STIIGPDQPVRIRTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDW 168
           + ++G    V I   V++K+D+EVEL VV+G     + ++ A  HV GYT+  DI+ARD 
Sbjct: 130 TAVVGHGGDVLIFPSVSEKIDYEVELAVVIGTTGRDIPKDRAFAHVFGYTILNDITARDV 189

Query: 169 QKEKNMGQFLLGKSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSI 228
           Q+ ++ GQ+  GKS+D  CP+GP ++T+DE+    +L +S S+NG L+Q+  T  ++  I
Sbjct: 190 QR-RHGGQYFKGKSLDGSCPIGPWIVTADEITDPQDLSISLSVNGELRQNGWTHDMIFDI 248

Query: 229 PSLLHRISSVMTLVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIG 279
           P+L+  +S  +TL PGD+I TGTP GVG    PP+YL+PGD +  +I  IG
Sbjct: 249 PTLIASLSEGLTLEPGDIIATGTPSGVGYAMDPPQYLKPGDTVICDIANIG 299


>UniRef50_A2W1T8 Cluster: 2-keto-4-pentenoate
           hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase;
           n=9; Proteobacteria|Rep: 2-keto-4-pentenoate
           hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase -
           Burkholderia cenocepacia PC184
          Length = 306

 Score =  175 bits (425), Expect = 1e-42
 Identities = 94/250 (37%), Positives = 148/250 (59%), Gaps = 6/250 (2%)

Query: 32  DSSLPTTLLQILRNG-DLEKVKKLKSTKPATIPLSSVTLTAPIHGVDKILCIGLNYKDHC 90
           D++ P  L  +L  G DL +V   +  +   + L +V +  P    +KILC+GLNY DH 
Sbjct: 45  DTAYPGDLDSLLAQGADLAEVAA-RLARGTPVDLDAVRVLPPFGRPNKILCVGLNYLDHS 103

Query: 91  QEQNLTPPPVPMVFSKFSSTIIGPDQPVRIRTDVTKKVDWEVELCVVVGREASCVREEDA 150
            E        P VF++F+S++IG DQP+ +    + ++D+E EL  V+G+    +  E A
Sbjct: 104 METGFAKQTYPTVFARFASSLIGHDQPIALPAQ-SSQLDYEGELVAVIGKAGRGITRERA 162

Query: 151 LQHVAGYTVAQDISARDWQKEKNMGQFLLGKSMDTFCPLGPCVLTSDEVGAAVE-LRVSC 209
           L HVAGY++  D++ RD+Q      Q+ +GK+ D     GP  +T+DE+    + LR+  
Sbjct: 163 LDHVAGYSLFNDVTLRDYQFRTP--QWTMGKNFDGTGGFGPWFVTADELPRGCKGLRIQT 220

Query: 210 SLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPGDLILTGTPGGVGMYRQPPEYLQPGD 269
            LNG + Q +ST+ ++  I +L+  +S VMTL  GDLI+TGTP G+GM R+P  +++ GD
Sbjct: 221 RLNGAVVQEASTSDMIFDIETLVVMLSEVMTLQAGDLIVTGTPAGIGMAREPQLWMKAGD 280

Query: 270 VLTSEIEKIG 279
           V   EIE++G
Sbjct: 281 VCEVEIEQLG 290


>UniRef50_Q0G5A5 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate
           isomerase; n=2; Proteobacteria|Rep:
           2-hydroxyhepta-2,4-diene-1,7-dioate isomerase -
           Fulvimarina pelagi HTCC2506
          Length = 337

 Score =  174 bits (423), Expect = 2e-42
 Identities = 95/231 (41%), Positives = 135/231 (58%), Gaps = 4/231 (1%)

Query: 51  VKKLKSTKPATIPL--SSVTLTAPIHGVDKILCIGLNYKDHCQEQNLTPPPVPMVFSKFS 108
           +K+L +  P ++P    S  L API  V   + IGLNY DH  E     P  P+VFSK  
Sbjct: 97  LKRLAAIDPKSLPKIDPSHRLGAPIARVGHFIAIGLNYADHAAETGADLPVEPLVFSKAP 156

Query: 109 STIIGPDQPVRIRTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDW 168
           S+I GP   + I    TK +DWEVEL VV+G  A  + E +A+ HVAG+ +  D+S R +
Sbjct: 157 SSICGPHDELPIPPGSTK-LDWEVELAVVIGERAYNINETEAMNHVAGFCLCNDVSERAF 215

Query: 169 QKEKNMGQFLLGKSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSI 228
           QKE+  GQF+ GKS      LGP ++T D +G   +L +  S+NG ++Q  +T  ++ S 
Sbjct: 216 QKERG-GQFIKGKSSPRTGALGPWLVTPDRLGDPQQLDLWLSVNGEIRQRGTTRDMLFSA 274

Query: 229 PSLLHRISSVMTLVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIG 279
             ++  +S  M L PGD+I TGTP GVG    PP++L+ GD+LT  I  +G
Sbjct: 275 AFIVSYLSKFMILEPGDVITTGTPSGVGAGMTPPQFLREGDILTLGIGGLG 325


>UniRef50_A1RQJ1 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate
           decarboxylase; n=5; Thermoprotei|Rep:
           5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase -
           Pyrobaculum islandicum (strain DSM 4184 / JCM 9189)
          Length = 310

 Score =  174 bits (423), Expect = 2e-42
 Identities = 98/240 (40%), Positives = 143/240 (59%), Gaps = 12/240 (5%)

Query: 48  LEKVKKL--KSTKPATIPLSSVTLTAPIHGVDKILCIGLNYKDHCQEQNLTPPPVPMVFS 105
           LE VKKL  ++  P   P   +    P+   +KILC+ +NY++H  E  + PP  P  F 
Sbjct: 66  LEIVKKLDERARGPFYKP-EEIKWEPPVPNPEKILCVAVNYREHGAETGIEPPDKPYFFP 124

Query: 106 KFSSTIIGPDQPVRIRTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISA 165
           KF + ++G +  V ++  V +K+DWEVEL VV+GR    +  E AL +V GYTV  D+S 
Sbjct: 125 KFPNALVGHEGYV-VKHRVVQKLDWEVELVVVMGRPGKYIEPERALDYVFGYTVGLDMSM 183

Query: 166 RDWQK--EKNMGQF----LLGKSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSS 219
           RDWQ   EK   Q+    + GK+MDT  P+GP + T DEV     L +   +NG L+Q  
Sbjct: 184 RDWQNPDEKTARQYGKNWIWGKTMDTAAPVGPYIATRDEVPDPNRLGLRLWVNGQLEQEG 243

Query: 220 STAQLVHSIPSLLHRISSVMTLVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIG 279
           +T+QL+ +I  L++  S  +TL PGDLI TGTP GVG  +   ++L+ GD++ +E+E IG
Sbjct: 244 NTSQLIFNIQQLIYWASQGITLRPGDLIFTGTPPGVGWAK--GKFLKGGDIVEAEVESIG 301


>UniRef50_A4SYH8 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate
           decarboxylase; n=1; Polynucleobacter sp.
           QLW-P1DMWA-1|Rep: 5-oxopent-3-ene-1,2,5-tricarboxylate
           decarboxylase - Polynucleobacter sp. QLW-P1DMWA-1
          Length = 299

 Score =  173 bits (422), Expect = 3e-42
 Identities = 92/257 (35%), Positives = 152/257 (59%), Gaps = 7/257 (2%)

Query: 30  KADSSLPTTLLQILRNGDLEKVKKL-KSTKPATIPL---SSVTLTAPIHGVDKILCIGLN 85
           K   + P TL Q+L+ G+ +   K+  S   + +P    S++T         KI+C+GLN
Sbjct: 36  KMKIAAPVTLDQLLQEGNAQGFNKVVASADQSGVPYLQESNITFGRLFKSPGKIVCVGLN 95

Query: 86  YKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRIRT-DVTKKVDWEVELCVVVGREASC 144
           Y+ H  E  +  P VP +F+K+++++   +  ++I    V+ K+D+E EL +V+G++   
Sbjct: 96  YRAHADEVGMVHPRVPPLFNKYNNSLAAHNCLLQIPPPSVSYKLDYETELLIVIGKQMRN 155

Query: 145 VREEDALQHVAGYTVAQDISARDWQKEKNMGQFLLGKSMDTFCPLGPCVLTSDEVGAAVE 204
           V E  AL +VAGY  + D S+RD Q E   GQ+++GK++D + P+GP  +T D VG    
Sbjct: 156 VPESAALDYVAGYCTSNDFSSRDLQLELPSGQWMIGKTLDQYAPIGPYFVTGDLVGNPNN 215

Query: 205 LRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPGDLILTGTPGGV--GMYRQPP 262
           L+V   +NG L+Q+S+T+  +H+   +L  IS+   L PGD++ TGTP GV  GM +   
Sbjct: 216 LQVKTWVNGELRQNSNTSDFIHNTQKMLSYISTYWALEPGDIVFTGTPQGVIAGMPKDKQ 275

Query: 263 EYLQPGDVLTSEIEKIG 279
            +L+ GD + S +EK+G
Sbjct: 276 VWLKKGDKVVSSVEKLG 292


>UniRef50_Q0S8P7 Cluster: Probable hydrolase; n=1; Rhodococcus sp.
           RHA1|Rep: Probable hydrolase - Rhodococcus sp. (strain
           RHA1)
          Length = 553

 Score =  173 bits (421), Expect = 4e-42
 Identities = 93/250 (37%), Positives = 147/250 (58%), Gaps = 19/250 (7%)

Query: 32  DSSLPTTLLQILRNGDLEKVKKLKSTKPATIPLSSVTLTAPIHGVDKILCIGLNYKDHCQ 91
           D+  P   LQ +  G    + +L ++ PA        L API     + C+G NY +H  
Sbjct: 30  DTGAPVRELQEIIAGGRAALGRLSTSTPA----EGGKLLAPITPHRNVFCVGRNYSEHAA 85

Query: 92  E------------QNLTPPPVPMVFSKFSSTIIGPDQPVRIRTDVTKKVDWEVELCVVVG 139
           E                 P  P+VF+K ++T+I    PV   TD+T  +D+E E+ +++G
Sbjct: 86  EFAESGFDATGSADGQHVPQYPVVFTKPAATVIACGDPVDPHTDITSALDYEGEIGIIIG 145

Query: 140 REASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLLGKSMDTFCPLGPCVLTSDEV 199
           + AS V  +DA+ +V GYT+  D++ARD Q++    Q+ +GKS+DTFCPLGP  +T+DE+
Sbjct: 146 KRASKVSRDDAMDYVWGYTLINDVTARDLQRDHK--QWFIGKSLDTFCPLGPWAVTADEI 203

Query: 200 GAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPGDLILTGTPGGVGMYR 259
               +L++   +NG L+Q ++TAQL+  +P+++  +S+ +TL PGD+I TGTP GVG+  
Sbjct: 204 DIN-DLQLQTRVNGELRQDTNTAQLIFDVPTIIETLSAGITLEPGDVIATGTPVGVGIGF 262

Query: 260 QPPEYLQPGD 269
            PP+YL  GD
Sbjct: 263 DPPKYLVEGD 272


>UniRef50_Q41AV1 Cluster: 5-carboxymethyl-2-hydroxymuconate
           delta-isomerase; n=1; Exiguobacterium sibiricum
           255-15|Rep: 5-carboxymethyl-2-hydroxymuconate
           delta-isomerase - Exiguobacterium sibiricum 255-15
          Length = 277

 Score =  173 bits (420), Expect = 6e-42
 Identities = 85/222 (38%), Positives = 131/222 (59%), Gaps = 3/222 (1%)

Query: 67  VTLTAPIHGVDKILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRIRTDVTK 126
           + L AP      ++C+G NY DH +E +       ++F+K  S+I+GP + +    D+T+
Sbjct: 58  IRLLAPYIPPRNVICVGKNYADHIKEMDTAGAGKFVLFTKAPSSIVGPFEAIERHADLTQ 117

Query: 127 KVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLLGKSMDTF 186
           ++D+E EL +++G     +  E+AL HV GY++  D++ARD QKE    QF  GKS+D F
Sbjct: 118 QLDYEGELAIIIGTSGRDLTPENALDHVFGYSIVNDVTARDLQKEH--VQFFRGKSLDGF 175

Query: 187 CPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPGDL 246
           CP GP ++T D      ++ V   +NG L+QS ST  ++  + ++L  +S  MTL  GD+
Sbjct: 176 CPFGPVIVTEDSFD-PTDVLVETRVNGQLRQSGSTKLMLRDVVTILTEVSRGMTLEAGDI 234

Query: 247 ILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIGAFDVRIEKF 288
           I TGTP GVG   +PP YLQ GDV+   IE IG     ++ +
Sbjct: 235 IATGTPAGVGHGMKPPTYLQDGDVVDISIEGIGHLQNHVKAY 276


>UniRef50_A7IDT5 Cluster: 5-carboxymethyl-2-hydroxymuconate
           Delta-isomerase; n=2; Proteobacteria|Rep:
           5-carboxymethyl-2-hydroxymuconate Delta-isomerase -
           Xanthobacter sp. (strain Py2)
          Length = 281

 Score =  173 bits (420), Expect = 6e-42
 Identities = 92/262 (35%), Positives = 147/262 (56%), Gaps = 6/262 (2%)

Query: 18  GYLEGDDIVDINKADSSLPTTLLQILRNGDLEKVKKLKSTKPATIPLSSVTLTAPIHGVD 77
           G +    I+D+ +     PT  L+    G L++   +    PA   LS VTL   I   D
Sbjct: 15  GLVTDGGIIDLTRRFPEAPT--LRTFIAGGLDRAAAVAGA-PADFALSEVTLAPVIPDPD 71

Query: 78  KILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRIRTDVTKKVDWEVELCVV 137
           KI+C+GLNY DH  E   T  P PM+F++++ + +G    + ++   + + D+E EL V+
Sbjct: 72  KIVCVGLNYHDHVNETGRTVTPNPMLFARYAGSQVGAGTAL-VKPLESDEFDYEGELAVI 130

Query: 138 VGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLLGKSMDTFCPLGPCVLTSD 197
           +G+    + E DAL HVAGY    D S RDWQ+  +  QF+ GK+       GP ++++D
Sbjct: 131 IGKAGRRISEADALSHVAGYACYNDASVRDWQRHTS--QFMPGKTFAATGAFGPWMVSAD 188

Query: 198 EVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPGDLILTGTPGGVGM 257
           E+     L ++  LNG   Q +S   ++  IP+L+   S+++ L+PGD+I++GTPGGVG 
Sbjct: 189 EIPDPTRLTLATRLNGAQVQHTSVDLMITPIPTLIAYTSTILPLLPGDVIVSGTPGGVGA 248

Query: 258 YRQPPEYLQPGDVLTSEIEKIG 279
            R P  +++ GDV+  E+  IG
Sbjct: 249 RRTPKLFMKDGDVVEVEVSGIG 270


>UniRef50_Q89GI5 Cluster: Bll6360 protein; n=157; Bacteria|Rep:
           Bll6360 protein - Bradyrhizobium japonicum
          Length = 314

 Score =  172 bits (419), Expect = 8e-42
 Identities = 96/228 (42%), Positives = 136/228 (59%), Gaps = 10/228 (4%)

Query: 60  ATIPLSSVTLTA-------PIHGVDKILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTII 112
           A +P+SS+ + A       P+ GV K + IGLNY DH  E  L  P  P+VF K  +++ 
Sbjct: 73  ARVPVSSLPVVAGTPRFGVPVSGVGKFVAIGLNYADHAAEAGLPLPSEPIVFQKAITSLS 132

Query: 113 GPDQPVRIRTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEK 172
           GP+  V +    + K DWEVEL +V+G  AS V   +ALQ+VAGY V  D+S R++Q E+
Sbjct: 133 GPNDAVVLPRG-SLKGDWEVELGIVIGSRASYVEPVEALQYVAGYCVVNDVSEREYQMER 191

Query: 173 NMGQFLLGKSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLL 232
             G +  GK  DTF P+GP ++T+DEV     L +   LNG   Q  +T  +V     ++
Sbjct: 192 G-GTWDKGKGCDTFGPVGPWLVTTDEVPDPGRLDIWLELNGRRMQQGNTRTMVFGCAGIV 250

Query: 233 HRISSVMTLVPGDLILTGTPGGVGMYRQP-PEYLQPGDVLTSEIEKIG 279
             +S  MTL+PGD+I TGTP GVGM  +P P YL+ GD++T  I+ +G
Sbjct: 251 SYVSQFMTLMPGDIIATGTPPGVGMGMKPDPIYLKVGDIMTLGIQGLG 298


>UniRef50_Q0RCN1 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate
           isomerase (HHDD isomerase)/5-
           carboxymethyl-2-oxo-hex-3-ene-1, 7-dioate decarboxylase;
           n=1; Frankia alni ACN14a|Rep:
           2-hydroxyhepta-2,4-diene-1,7-dioate isomerase (HHDD
           isomerase)/5- carboxymethyl-2-oxo-hex-3-ene-1, 7-dioate
           decarboxylase - Frankia alni (strain ACN14a)
          Length = 276

 Score =  172 bits (419), Expect = 8e-42
 Identities = 86/218 (39%), Positives = 125/218 (57%), Gaps = 3/218 (1%)

Query: 62  IPLSSVTLTAPIHGVDKILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRIR 121
           +PL    L   +    KI+C+GLNY  H +E   TPP  P +F+K++  +IGP   + + 
Sbjct: 53  LPLDGADLAPLVPAPPKIICMGLNYATHLKEMGRTPPTHPTLFAKYTRALIGPTDDILV- 111

Query: 122 TDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLLGK 181
             VT+ VDWE EL  V+G       E  A + +AGYT+  D++ RDWQ      QFL GK
Sbjct: 112 PPVTEAVDWEGELAFVIGTTVRFADEAAAREAIAGYTIMNDVTMRDWQFRTL--QFLQGK 169

Query: 182 SMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTL 241
           S +   PLGP ++T DE+    +L +   +NG + Q S T+ L+     ++  +S  +TL
Sbjct: 170 SFEGSTPLGPALVTPDELDNPADLALRTLVNGEVMQKSRTSDLLFPPVEIVRYVSQFITL 229

Query: 242 VPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIG 279
            PGD++ TGTPGGVG  R P  YL  GDV+T ++E +G
Sbjct: 230 EPGDVLTTGTPGGVGHGRNPKVYLADGDVVTVDVEGLG 267


>UniRef50_A0K0J6 Cluster: 5-carboxymethyl-2-hydroxymuconate
           delta-isomerase; n=5; Actinomycetales|Rep:
           5-carboxymethyl-2-hydroxymuconate delta-isomerase -
           Arthrobacter sp. (strain FB24)
          Length = 290

 Score =  172 bits (418), Expect = 1e-41
 Identities = 100/240 (41%), Positives = 144/240 (60%), Gaps = 6/240 (2%)

Query: 43  LRNGDLEKVKK-LKSTKPATIP-LSSVTLTAPIHGVDKILCIGLNYKDHCQEQNLTPPPV 100
           L  G +++V+  L +   A IP   S+ L AP+     ++ IGLNY  H  E     P V
Sbjct: 42  LGTGGIDRVRDALAAGDLAEIPDAGSLRLGAPLSRPGAVVGIGLNYAGHAAESGAAVPEV 101

Query: 101 PMVFSKFSSTIIGPDQPVRIRTDVTKKVDWEVELCVVVGREASCVREED-ALQHVAGYTV 159
           P+VF K S+T+ GP     I   +++K DWEVEL VV+G+ AS ++  D A   VAGY +
Sbjct: 102 PVVFLKPSNTVAGPFDDAPI-PPLSRKYDWEVELAVVIGQRASYLKSVDEAAGCVAGYVL 160

Query: 160 AQDISARDWQKEKNMGQFLLGKSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSS 219
           A D+S RD+Q     GQ++ GKS+    PLGP  + + ++  +  LR+   +NG L+Q S
Sbjct: 161 ANDLSERDYQLPGAAGQWVKGKSLPASTPLGPWFVPAADLDPSA-LRLRTWVNGELRQDS 219

Query: 220 STAQLVHSIPSLLHRISSVMTLVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIG 279
           STA L+  +P+++H +S  M L PGD+ILTGTP GV +  + P YLQ GDVL  E+E +G
Sbjct: 220 STADLIFDVPAVVHHLSQFMVLEPGDVILTGTPEGVALSGRFP-YLQDGDVLELEVEGLG 278


>UniRef50_A3XC82 Cluster: 5-carboxymethyl-2-hydroxymuconate
           delta-isomerase; n=3; Alphaproteobacteria|Rep:
           5-carboxymethyl-2-hydroxymuconate delta-isomerase -
           Roseobacter sp. MED193
          Length = 285

 Score =  171 bits (416), Expect = 2e-41
 Identities = 85/234 (36%), Positives = 133/234 (56%), Gaps = 5/234 (2%)

Query: 49  EKVKKLKSTKPATIPLSSVT---LTAPIHGVDKILCIGLNYKDHCQEQNLTPPPVPMVFS 105
           E + +L S  PAT+P++ V    L  P+     I C+GLNY DH  E  L  P  P++F+
Sbjct: 42  EMLTRLASVDPATLPMADVAGKPLAPPVAQPLNIWCVGLNYSDHAAEAGLPVPEEPILFN 101

Query: 106 KFSSTIIGPDQPVRIRTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISA 165
           K + T  GP+  + +++    K+DWEVEL +V+ + A  +  + A+ H+AG+ +  DIS 
Sbjct: 102 KSTVTYCGPNDDI-LKSAQMSKLDWEVELGIVISKPALNISRDQAMDHIAGFVLVNDISE 160

Query: 166 RDWQKEKNMGQFLLGKSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLV 225
           R WQ E++ GQ++ GKS   FCP GP + T +E      L +   +NG   Q+ +T  ++
Sbjct: 161 RAWQMERS-GQWVKGKSFPNFCPTGPVLATKEEFADVQNLGMWLDVNGERMQTGNTGTMI 219

Query: 226 HSIPSLLHRISSVMTLVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIG 279
             + +++  +S    L PGDLI TGTP GVG    PP +L  GD ++  I+ +G
Sbjct: 220 FDVATIVSYMSEFTRLEPGDLICTGTPPGVGAGMTPPVWLNEGDKVSLGIDGLG 273


>UniRef50_Q4FMJ2 Cluster: Fumarylacetoacetate hydrolase family
           protein; n=2; Candidatus Pelagibacter ubique|Rep:
           Fumarylacetoacetate hydrolase family protein -
           Pelagibacter ubique
          Length = 281

 Score =  171 bits (415), Expect = 2e-41
 Identities = 83/204 (40%), Positives = 131/204 (64%), Gaps = 2/204 (0%)

Query: 82  IGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRIRTDVTKKVDWEVELCVVVGRE 141
           IGLNY +H +E     P  P++F+K   +I+GP+  V I    +KK+D EVE+  V+G++
Sbjct: 76  IGLNYVEHAKETGAKTPDNPVLFNKSVHSIVGPNDNVII-PKTSKKLDHEVEIAFVIGKK 134

Query: 142 ASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLLGKSMDTFCPLGPCVLTSDEVGA 201
           A  V E+DA  ++ GY +  DIS R+WQKEK  GQ++ GKS DTF PLGP ++T DE+  
Sbjct: 135 AKRVLEKDAQDYIFGYCICNDISEREWQKEKG-GQWVKGKSGDTFGPLGPYLVTKDEIQD 193

Query: 202 AVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPGDLILTGTPGGVGMYRQP 261
              L ++  +NG   Q+ +T Q++ +   L+  I+S +TL+PGD++ TGTP GVG+   P
Sbjct: 194 VNNLNLTLDVNGHRHQTGNTNQMIFNFNFLVAHITSFITLMPGDIVTTGTPPGVGLGMDP 253

Query: 262 PEYLQPGDVLTSEIEKIGAFDVRI 285
           P +L+ GD +   I+ +G+ + ++
Sbjct: 254 PVFLKEGDEMKLNIDSLGSQNSKV 277


>UniRef50_Q5Z0F5 Cluster: Putative hydrolase; n=1; Nocardia
           farcinica|Rep: Putative hydrolase - Nocardia farcinica
          Length = 285

 Score =  169 bits (412), Expect = 5e-41
 Identities = 94/222 (42%), Positives = 125/222 (56%), Gaps = 7/222 (3%)

Query: 65  SSVTLTAPIHGVDKILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRIRTDV 124
           S+  +TAP     KI+C G NY+ H  E     P  P +F+KF+ T+   D  + +    
Sbjct: 53  SAPVVTAP----RKIVCCGHNYRAHIAELGRAEPEFPTLFAKFADTLTAWDADITLGMAA 108

Query: 125 TKK-VDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLLGKSM 183
               +DWE EL VVVG E        A   +AGYTVA D S R WQ+     Q+L GK+ 
Sbjct: 109 ADAGLDWEAELAVVVGAELRRADRATARAGIAGYTVANDFSVRTWQRRT--AQWLQGKAF 166

Query: 184 DTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVP 243
           D   PLGP ++T DE      LR++C +NGV++Q  ST  L+    +LL  IS+  TL P
Sbjct: 167 DATTPLGPDLVTPDEADPGDGLRITCRVNGVVEQCGSTDDLLFDPAALLSYISAFTTLRP 226

Query: 244 GDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIGAFDVRI 285
           GD++LTGTPGGVG+   PP +L  GDV+ +EIE IG    RI
Sbjct: 227 GDVVLTGTPGGVGVAADPPRHLGDGDVVETEIEGIGLLRNRI 268


>UniRef50_A5AB73 Cluster: Function: E. coli hpaG is a bifunctional
           decarboxylase/isomerase; n=4; Pezizomycotina|Rep:
           Function: E. coli hpaG is a bifunctional
           decarboxylase/isomerase - Aspergillus niger
          Length = 358

 Score =  169 bits (412), Expect = 5e-41
 Identities = 84/208 (40%), Positives = 129/208 (62%), Gaps = 3/208 (1%)

Query: 69  LTAPIHGVDKILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRIRTDVTKKV 128
           L  P+     ++CIGLNYK H +E +L  P  P VF+K +  + GP + + I  D    +
Sbjct: 54  LLPPVPNTPLVICIGLNYKQHAKEASLDVPTYPPVFTKPADVLAGPFETIPIHRDAQSHL 113

Query: 129 DWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQ-KEKNMGQFLLGKSMDTFC 187
           D+E EL VV+G++A  V  EDAL +V GYT   D+SAR++Q  E + GQF   KS D F 
Sbjct: 114 DYEGELTVVIGKDAKNVSAEDALDYVLGYTAGNDLSARNFQMPEASGGQFCYAKSFDKFA 173

Query: 188 PLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPGDLI 247
           P+G  ++++ EV    +L +   +NGV+KQ+++T+ ++  +  ++  +S  MTL  G LI
Sbjct: 174 PIGHVLVSAQEVQDPQQLSLVTKVNGVVKQTTNTSDMIWGVRDIVSHLSRGMTLRKGTLI 233

Query: 248 LTGTPGGVGMYRQPPEYLQPGDVLTSEI 275
           +TGTP GVG +R+  E+LQ GDV+  E+
Sbjct: 234 MTGTPSGVGFFRK--EFLQDGDVVEVEL 259


>UniRef50_Q4J809 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=4;
           Thermoprotei|Rep: Fumarylacetoacetate (FAA) hydrolase -
           Sulfolobus acidocaldarius
          Length = 307

 Score =  169 bits (412), Expect = 5e-41
 Identities = 104/301 (34%), Positives = 168/301 (55%), Gaps = 26/301 (8%)

Query: 1   MKLVQFSYKDSPKNIRVGYLEGDDIVDINKA-----DSSLPT---TLLQILRNGD----- 47
           MKL+QFS  +  +  R+G      +VD+ KA     D++ P     +  ++  G+     
Sbjct: 1   MKLLQFS-PNLGEQKRIGVYHEGKVVDLVKAYEMVYDATPPNWFFNMRDLIEGGEGSLYL 59

Query: 48  ----LEKVKKLKST--KPATIPLSSVTLTAPIHGVDKILCIGLNYKDHCQEQNLTPPPVP 101
               L+   KL S   + A +   ++    P+   +KI  + +NY+ H QE N  PP  P
Sbjct: 60  VRRVLDDFNKLDSVIKRSAELDPENIIYYPPVTDPEKIFLLAVNYRAHGQETNNNPPKEP 119

Query: 102 MVFSKFSSTIIGPDQPVRIRTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQ 161
            +F+KF++T+IG +QPV +    + KVD+E+EL V++G+ A  V    AL +V GYT+  
Sbjct: 120 YIFTKFNNTLIGHNQPV-LFPRASNKVDYEIELAVIMGKRAKYVNSSKALDYVFGYTIFN 178

Query: 162 DISARDWQ--KEKNMG-QFLLGKSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQS 218
           DIS RD Q   E   G +++ GK +DT  P+GP ++T DE+     LR+   +NG ++Q 
Sbjct: 179 DISFRDKQFPPEIPYGMRWVHGKGLDTAAPMGPWIVTKDEIDNINNLRLKLRVNGEIRQD 238

Query: 219 SSTAQLVHSIPSLLHRISSVMTLVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKI 278
           +    ++  +  ++  +S+ +TL PGD+I TGTP GV +     +YL+PGDV+ +EI KI
Sbjct: 239 AYAEDMIFKVEQIIEYLSNGITLKPGDVISTGTPSGVAL--ATGKYLKPGDVMEAEISKI 296

Query: 279 G 279
           G
Sbjct: 297 G 297


>UniRef50_A7DRD3 Cluster: 5-carboxymethyl-2-hydroxymuconate
           Delta-isomerase; n=1; Candidatus Nitrosopumilus
           maritimus SCM1|Rep: 5-carboxymethyl-2-hydroxymuconate
           Delta-isomerase - Candidatus Nitrosopumilus maritimus
           SCM1
          Length = 289

 Score =  169 bits (412), Expect = 5e-41
 Identities = 94/253 (37%), Positives = 144/253 (56%), Gaps = 5/253 (1%)

Query: 35  LPTTLLQILRNGDLEKVKKLKSTKPATIPLSSVTLTAPIHGVDKILCIGLNYKDHCQEQN 94
           +P  +   L +G  +++K      P    LS   L API   +KI+C+  NY DH +EQ 
Sbjct: 36  IPHNVKDFLFDGWFDEIKNKIQDLPYEENLSKFKLLAPIPNPNKIICLAFNYVDHAKEQG 95

Query: 95  LTPPPVPMVFSKFSSTIIGPDQPVRIRTDVTKKVDWEVELCVVVGREASCVREEDALQHV 154
           LT P  P +  K  + + G +  +     VT+ +D+EVEL +++G+    +  E+A   V
Sbjct: 96  LTAPEDPAIVIKPRTALNGNNANIECPDFVTQ-LDYEVELALIIGKNCKNISVEEAQNVV 154

Query: 155 AGYTVAQDISARDWQ-KEKNMGQFLLGKSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNG 213
            GY V  D+SARD Q K+K   QF  GKS D+F P GP + T+DE+     L+++  +NG
Sbjct: 155 FGYMVFNDVSARDIQFKDK---QFTRGKSFDSFAPCGPWITTADEIQEPQNLKLTTKING 211

Query: 214 VLKQSSSTAQLVHSIPSLLHRISSVMTLVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTS 273
            L+Q+SST+ +   IP ++ +IS VMTL  GD+I TGTP GV + +    +L+ GD +  
Sbjct: 212 ELRQNSSTSNMFIKIPEIISKISKVMTLEKGDIISTGTPAGVMLNKPNAIFLKDGDKVEM 271

Query: 274 EIEKIGAFDVRIE 286
           EIE +G  +  I+
Sbjct: 272 EIEGLGVLNNTIK 284


>UniRef50_A4SYK1 Cluster: Fumarylacetoacetate (FAA) hydrolase
           precursor; n=3; Proteobacteria|Rep: Fumarylacetoacetate
           (FAA) hydrolase precursor - Polynucleobacter sp.
           QLW-P1DMWA-1
          Length = 349

 Score =  169 bits (411), Expect = 7e-41
 Identities = 91/256 (35%), Positives = 149/256 (58%), Gaps = 13/256 (5%)

Query: 36  PTTLLQILRNGD---LEKVKKLKSTKPATIPLSSVTLTAPIHGVD-KILCIGLNYKDHCQ 91
           PT+++ +  +G+   L+     K+       ++ V L +PI      I C+G NY DH +
Sbjct: 88  PTSMISLAGSGNQGLLQLAAIFKNRGSNLANVNQVILLSPIPKPQANIYCVGWNYLDHFE 147

Query: 92  E--------QNLTPPPVPMVFSKFSSTIIGPDQPVRIRTDVTKKVDWEVELCVVVGREAS 143
           E             P VP++F+K + T+ GP   +     ++  +DWE EL VV+G++  
Sbjct: 148 EGLKHRADTAVKEYPKVPVLFTKGTQTMNGPFDNIPYDAGISTMIDWEAELAVVIGKKGK 207

Query: 144 CVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLLGKSMDTFCPLGPCVLTSDEVGAAV 203
            + EE+A+ +V GY+   D +ARD Q+++  GQ+  GKS+D   P+GP V+T+  V    
Sbjct: 208 NISEENAMDYVFGYSAYNDTTARDIQQKRQSGQWFKGKSLDGHGPMGPWVVTAGGVNLD- 266

Query: 204 ELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPGDLILTGTPGGVGMYRQPPE 263
           + R+ CS+NGV KQ++S  Q+   IP+++  +S  +TL+PGD+I TGTP GVG  R P E
Sbjct: 267 DTRIICSVNGVEKQNASYKQMYFKIPAIIAELSRGLTLLPGDIIATGTPSGVGAGRTPQE 326

Query: 264 YLQPGDVLTSEIEKIG 279
           +++PGD++ + I  IG
Sbjct: 327 FMKPGDMMETNITGIG 342


>UniRef50_Q7WM74 Cluster: Putative hydrolase; n=3;
           Burkholderiales|Rep: Putative hydrolase - Bordetella
           bronchiseptica (Alcaligenes bronchisepticus)
          Length = 304

 Score =  169 bits (410), Expect = 9e-41
 Identities = 87/223 (39%), Positives = 131/223 (58%), Gaps = 9/223 (4%)

Query: 64  LSSVTLTAPIHGVDKILCIGLNYKDHCQEQNLTP-------PPVPMVFSKFSSTIIGPDQ 116
           L +V +  P+     + C+G NY++H  E NL         P     F+K  + +IG   
Sbjct: 76  LQAVRVLPPLPMARNVFCVGRNYREHIIEGNLARGRPANSFPEAIEFFTKAPTAVIGHGG 135

Query: 117 PVRIRTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQ 176
            V+    +T  +D+EVEL +V+GR  + +  E AL HV GYT+  DI+ARD Q     GQ
Sbjct: 136 HVKRHAGLTDSLDYEVELAIVIGRAGADIPREKALDHVFGYTIVNDITARDLQARH--GQ 193

Query: 177 FLLGKSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRIS 236
           +  GKS+DT CP+GP V+    +  A  L VS S+NG L+Q  +T+ ++  + +++ ++S
Sbjct: 194 WFKGKSLDTSCPMGPVVVHRSAIPDANNLAVSLSVNGELRQQDNTSDMIFDVAAVVAQLS 253

Query: 237 SVMTLVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIG 279
           + MTL+PGD+I TGTP GVG    PP  LQ GDV+++ +E IG
Sbjct: 254 AGMTLLPGDVIATGTPKGVGFALTPPRCLQVGDVVSASVEHIG 296


>UniRef50_A3YEW7 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate
           decarboxylase; n=3; Proteobacteria|Rep:
           5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase -
           Marinomonas sp. MED121
          Length = 298

 Score =  169 bits (410), Expect = 9e-41
 Identities = 92/262 (35%), Positives = 153/262 (58%), Gaps = 7/262 (2%)

Query: 20  LEGDDIVDINKADSSLPTTLLQILRNGDL-EKVKKLKSTKPATIPLSSVTLTAPIHGVDK 78
           ++G+  ++I+  D+   + L QI+ N  L EK+    S  P  IP+S +  + P+    K
Sbjct: 25  IQGELAINISSQDNQFGSDLSQIINNPQLLEKISGYSSA-PG-IPVSQIQPSLPLQHPGK 82

Query: 79  ILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRIRTDVTKKVDWEVELCVVV 138
           ++C+GLNY DH +E     P  P +F +  S+++ P Q   +R  V+ ++D+E EL ++V
Sbjct: 83  VICLGLNYMDHIKEGGYKVPDYPALFMRSHSSLM-PAQAPMVRPKVSVQLDYEAELMLIV 141

Query: 139 GREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLLGKSMDTFCPLGPCVLTSDE 198
           G+    + E  AL +V GYT+  D S RD+Q++ +  Q+  GK+ D    +GP ++T DE
Sbjct: 142 GKHGRHIPESKALDYVFGYTIFNDGSVRDYQRKTH--QWTPGKNFDNTGAIGPIIVTPDE 199

Query: 199 VGAAVE-LRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPGDLILTGTPGGVGM 257
           +      L++   +   + QS++T++++ S+  ++  ISS  TL PGDLI  GTP GVG 
Sbjct: 200 LPEGAHGLKIETRVGDEILQSANTSEMLWSVARVIAEISSYTTLEPGDLIAMGTPPGVGH 259

Query: 258 YRQPPEYLQPGDVLTSEIEKIG 279
            R P  +L+PG+V+  EIE IG
Sbjct: 260 ARSPARWLEPGEVVEVEIEGIG 281


>UniRef50_Q8RCZ4 Cluster: 2-keto-4-pentenoate
           hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase;
           n=8; cellular organisms|Rep: 2-keto-4-pentenoate
           hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase -
           Thermoanaerobacter tengcongensis
          Length = 242

 Score =  168 bits (409), Expect = 1e-40
 Identities = 98/238 (41%), Positives = 143/238 (60%), Gaps = 14/238 (5%)

Query: 49  EKVKKLKSTKPATIPLSSVTLTAPIHGVDKILCIGLNYKDHCQEQNLTPPPVPMVFSKFS 108
           +KV  LK  +     L+ V L  P     K +C+GLNYKDH +E     P  P +F K S
Sbjct: 19  DKVILLKEGETFLYGLNEVKLLPPCIP-SKAICVGLNYKDHIEEMGDKIPEEPTLFIKPS 77

Query: 109 STIIGPDQPVRIRTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDW 168
           + +IGPD  + I  +++++VD+E EL VV+GR+A  V  E+A  ++ GYT+A D++ARD 
Sbjct: 78  TAVIGPDDYI-ILPEMSRRVDYEGELAVVIGRKAKNVSIEEAKNYILGYTIANDVTARDL 136

Query: 169 QKEKNMGQFLLGKSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSI 228
           Q +   GQ+   KS DTF P+GP ++T  +      L ++  +NG +KQ S+T  L+ ++
Sbjct: 137 QAKD--GQWTRAKSFDTFLPIGPWIVTDLD---PTSLNITTYVNGEVKQKSNTKYLIFNV 191

Query: 229 PSLLHRISSVMTLVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIGAFDVRIE 286
             L+  IS +MTL PGD+ILTGTP GVG        L+ GDV+T EIE IG    R++
Sbjct: 192 FKLVSFISHIMTLNPGDVILTGTPSGVGP-------LKSGDVVTIEIEGIGKLTNRVK 242


>UniRef50_Q88Y59 Cluster:
           2-hydroxyhepta-2,4-diene-1,7-dioateisomerase /
           5-carboxymethyl-2-oxo-
           hex-3-ene-1,7-dioatedecarboxylase; n=1; Lactobacillus
           plantarum|Rep:
           2-hydroxyhepta-2,4-diene-1,7-dioateisomerase /
           5-carboxymethyl-2-oxo- hex-3-ene-1,7-dioatedecarboxylase
           - Lactobacillus plantarum
          Length = 276

 Score =  168 bits (409), Expect = 1e-40
 Identities = 83/218 (38%), Positives = 128/218 (58%), Gaps = 3/218 (1%)

Query: 69  LTAPIHGVDKILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRIRTDVTKKV 128
           L API    +I  +G+NY+DH  E ++T P VP +F+KFSS++   +  +      T   
Sbjct: 62  LAAPITAPRQIFAVGMNYRDHSAEIHITLPKVPSIFTKFSSSLAPANVTMATHGPET--- 118

Query: 129 DWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLLGKSMDTFCP 188
           DWE EL V++G+    +   DA+ HVAG  V +D+S R  Q E +  QF +GKS + + P
Sbjct: 119 DWETELVVMIGKGGRDIATADAMAHVAGVMVGEDLSDRAVQFENDNPQFSIGKSFENYAP 178

Query: 189 LGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPGDLIL 248
           +GP + T DE+    +  ++ ++NG   Q +  +QL+  +P L+H +S+V  L PGDLI 
Sbjct: 179 VGPWLTTVDELANLDDEVITTTVNGQTMQQAPLSQLIFKVPDLVHYLSTVCELQPGDLIF 238

Query: 249 TGTPGGVGMYRQPPEYLQPGDVLTSEIEKIGAFDVRIE 286
           TGTP G G+ R P  +LQ GD L  +I  +G  ++ I+
Sbjct: 239 TGTPSGTGVGRNPQVFLQAGDQLCGQITHLGTLNITIK 276


>UniRef50_A1DM45 Cluster: Fumarylacetoacetate hydrolase family
           protein; n=5; Pezizomycotina|Rep: Fumarylacetoacetate
           hydrolase family protein - Neosartorya fischeri (strain
           ATCC 1020 / DSM 3700 / NRRL 181)(Aspergillus
           fischerianus (strain ATCC 1020 / DSM 3700 / NRRL 181))
          Length = 289

 Score =  168 bits (409), Expect = 1e-40
 Identities = 88/216 (40%), Positives = 130/216 (60%), Gaps = 4/216 (1%)

Query: 69  LTAPIHGVD--KILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGP--DQPVRIRTDV 124
           L AP+   D   + C+GLNY+ H +E NL  P  P++F K  ++I GP  D P+      
Sbjct: 60  LLAPLARKDIRTVRCLGLNYEQHARESNLPIPKYPVLFYKPVTSIAGPRDDIPISTMAQE 119

Query: 125 TKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLLGKSMD 184
            + +D+E EL +V+G+EA  V E  AL +V GY V  D+S RDWQ ++  GQ+ LGK  D
Sbjct: 120 GEGLDYECELVIVIGKEAKDVPESRALDYVLGYAVGNDVSHRDWQIKRGGGQWGLGKGFD 179

Query: 185 TFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPG 244
            + P GP +++S  +     L +S  LNG + QSSST  ++ S+  ++  +S   TL+PG
Sbjct: 180 GWAPFGPGIVSSRLIRDPNALHISTRLNGQVVQSSSTKDMIFSVAKVVAFLSQGTTLLPG 239

Query: 245 DLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIGA 280
           DLI TGTP GVGM R+P  +L+ GD +   +E +G+
Sbjct: 240 DLIFTGTPQGVGMGRKPALWLKDGDQVEVSLEGVGS 275


>UniRef50_A0V486 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate
           decarboxylase; n=4; Bacteria|Rep:
           5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase -
           Delftia acidovorans SPH-1
          Length = 309

 Score =  166 bits (403), Expect = 7e-40
 Identities = 87/247 (35%), Positives = 131/247 (53%), Gaps = 3/247 (1%)

Query: 39  LLQILRNGDLEKVKKLKSTKPATIPLSSVTLTAPIHGVDKILCIGLNYKDHCQEQNLTPP 98
           LL +LR   L ++++       ++  +       I    K++C+GLNYK H  E      
Sbjct: 59  LLSVLRAQALGELEQALQAGAVSVDAAQTQALPVIPNPGKLICVGLNYKTHVAETRRADS 118

Query: 99  PVPMVFSKFSSTIIGPDQPVRIRTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYT 158
             P +F +F+ ++   D    +R   +++ DWE EL  V+GR    + +EDA  H+AGY 
Sbjct: 119 EHPSLFLRFNDSLAA-DGDELLRPAFSERFDWEGELAFVIGRGGRHIAKEDAFDHIAGYA 177

Query: 159 VAQDISARDWQKEKNMGQFLLGKSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQS 218
              D+S RDWQ+  +  QF  GK+     P GP ++T DEV     L +   LNG + Q 
Sbjct: 178 CFNDVSVRDWQRHTH--QFTPGKNFPGTAPFGPWLVTRDEVADVRSLALQTRLNGSVMQQ 235

Query: 219 SSTAQLVHSIPSLLHRISSVMTLVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKI 278
           +S   L+  IP+++  +S    L PGD+I TGTPGGVG  R+PP Y++ GDV+  EI  +
Sbjct: 236 ASLGDLIFDIPTIVAYVSRFTPLSPGDVIATGTPGGVGDRREPPLYMKHGDVVEVEITGL 295

Query: 279 GAFDVRI 285
           G    RI
Sbjct: 296 GVLRNRI 302


>UniRef50_Q2U1K8 Cluster: RIB40 genomic DNA, SC138; n=4;
           Pezizomycotina|Rep: RIB40 genomic DNA, SC138 -
           Aspergillus oryzae
          Length = 582

 Score =  166 bits (403), Expect = 7e-40
 Identities = 98/281 (34%), Positives = 161/281 (57%), Gaps = 20/281 (7%)

Query: 16  RVGYLE-GDDIVDINKADSSLP-TTLLQILRNGDLEKVKKLKSTKPATIPLSSVTLTAPI 73
           R+G+L+    +V      S  P T L Q++  G+    + +K++   +  LSSV    PI
Sbjct: 20  RIGHLDFRTSMVTPLSFKSGTPLTNLYQVITVGE----QGIKASGAQSFLLSSVKHLPPI 75

Query: 74  HGVDKILCIGLNYKDHCQEQNLT---------PPPVPMVFSKFSSTIIGPDQPVRIRTDV 124
            G D +L +G NY +H +E N +          P  P++F+K +++IIGP++P+ +    
Sbjct: 76  SGRD-VLAVGKNYVEHAKEFNASGYDASDKSDQPTHPVIFTKRATSIIGPEEPILLHPKF 134

Query: 125 TKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLLGKSMD 184
           T  VD+E E+ V++G+    + EE+A  HV GYT+  D++AR+ Q++    QF LGKS D
Sbjct: 135 TSTVDYEGEIGVIIGKPGFQISEENASDHVWGYTIVNDMTARERQRDHK--QFFLGKSPD 192

Query: 185 TFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPG 244
           TFCP+GP  +  + +     L++   +N  L+Q +S + L+ SIP+L+  IS+  TL  G
Sbjct: 193 TFCPMGPVAVPKESL--PENLKIQTFVNQELRQEASLSDLIFSIPTLIATISAGQTLQTG 250

Query: 245 DLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIGAFDVRI 285
           D+I TGTP GVG   +P ++LQ GD ++  +  +G    R+
Sbjct: 251 DVIATGTPAGVGFGFRPMKFLQTGDEISVSVTGLGTLTNRM 291


>UniRef50_A4WEA8 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate
           decarboxylase; n=6; Enterobacteriaceae|Rep:
           5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase -
           Enterobacter sp. 638
          Length = 287

 Score =  165 bits (402), Expect = 9e-40
 Identities = 97/280 (34%), Positives = 150/280 (53%), Gaps = 12/280 (4%)

Query: 1   MKLVQFSYKDSPKNIRVGYLEGDDIVDINKADSSLPTTLLQILR-NGDLEKVKKLKSTKP 59
           MKL  F YK        G ++ D +V++ +      + L  +L+ NG  E  + L     
Sbjct: 1   MKLASFIYKGQRS---YGIVKADGVVNLGRRLGDRFSDLKALLQGNGMAEATRYLNDA-- 55

Query: 60  ATIPLSSVTLTAPIHGVDKILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVR 119
             +PL ++T    I   +KILC+G+NY +  QE +    P P +F +F  +  G + PV 
Sbjct: 56  VDVPLDAITFLPVIEHPEKILCVGMNYAEKRQEFD-QHNPAPTLFVRFPDSQTGHNSPV- 113

Query: 120 IRTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLL 179
           ++   + + D+E EL V++G+    +  +DAL+HVAGY+   D SARDWQ       F  
Sbjct: 114 LKPRHSSEFDYEGELAVIIGKGGENISRDDALRHVAGYSCYMDGSARDWQHT----WFTA 169

Query: 180 GKSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVM 239
           GK+       GP + T+DE+     L +   LNG + Q  +T+ ++H +  L+  IS+  
Sbjct: 170 GKNWRQTGAFGPWMATADEIPDPHRLAIRTWLNGRMVQEDNTSSMIHKVAELIEYISTFT 229

Query: 240 TLVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIG 279
            L PGD+I+TG+PGGVG  R PP ++Q GD +  EIE IG
Sbjct: 230 RLSPGDVIITGSPGGVGKKRNPPLFMQEGDRIEVEIENIG 269


>UniRef50_A3VFY9 Cluster: 5-carboxymethyl-2-hydroxymuconate
           delta-isomerase; n=1; Rhodobacterales bacterium
           HTCC2654|Rep: 5-carboxymethyl-2-hydroxymuconate
           delta-isomerase - Rhodobacterales bacterium HTCC2654
          Length = 279

 Score =  165 bits (402), Expect = 9e-40
 Identities = 101/283 (35%), Positives = 153/283 (54%), Gaps = 14/283 (4%)

Query: 4   VQFSYKDSPKNIRVGYLEGDDIVDINKADSSLPTTLLQILRNGDLEKVKKLKSTKPATIP 63
           ++F+  +    +R G +EGD I    + D       L+   +GDL  +      +PA + 
Sbjct: 1   MKFATIEHGGQLRFGLVEGDAIHLAPEGDR------LRAHLDGDLAALATRLRGEPA-LS 53

Query: 64  LSSVTLTAPIHGVDKILCIGLNYKDHCQEQN----LTPPPVPMVFSKFSSTIIGPDQPVR 119
           L+ VT T  +    ++LCIGLNYKDH  E       T P  P+VF +F++++    + + 
Sbjct: 54  LAGVTYTPVVPDAQQVLCIGLNYKDHRAETKGEVGTTYPDNPIVFMRFATSLAAHGESLP 113

Query: 120 IRTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLL 179
           I   V++ VD+E EL V++G+    + + DA+ HVAGY    DIS RDWQ +    Q+  
Sbjct: 114 I-PKVSEVVDYEAELAVIIGKGGRYIAKADAMSHVAGYAPFNDISMRDWQMKGE--QWGP 170

Query: 180 GKSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVM 239
           GK+     P GP ++T DEVG   E  +   L+G + Q S    L+  IP+L+   S+ +
Sbjct: 171 GKNFPKSGPFGPVMVTPDEVGDLGETGIRLILDGEVLQESWIKHLIFDIPTLISYCSNFV 230

Query: 240 TLVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIGAFD 282
            L PGD+I+TGTPGGVG  R+PP  L PG     E++ IG  +
Sbjct: 231 ELRPGDVIVTGTPGGVGFVRKPPILLAPGKTCVVEVDGIGRLE 273


>UniRef50_Q59050 Cluster: Uncharacterized protein MJ1656; n=4;
           Euryarchaeota|Rep: Uncharacterized protein MJ1656 -
           Methanococcus jannaschii
          Length = 237

 Score =  165 bits (402), Expect = 9e-40
 Identities = 82/202 (40%), Positives = 131/202 (64%), Gaps = 13/202 (6%)

Query: 78  KILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRIRTDVTKKVDWEVELCVV 137
           KI+C+GLNY DH +E N+  P  P++F K +S II  +  + IR  ++K+VD+EVEL +V
Sbjct: 39  KIICVGLNYIDHAKELNMEIPEYPIIFLKPTSAIIYNEDYI-IRPRISKRVDYEVELAIV 97

Query: 138 VGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLLGKSMDTFCPLGPCVLTSD 197
           +G++   +++++A  ++ GYT+  D++ARD Q++   GQ+   KS DTFCP+GP ++   
Sbjct: 98  IGKKCKNIKKDEANDYIMGYTILNDVTARDLQQKD--GQWTRAKSFDTFCPIGPRIVKDI 155

Query: 198 EVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPGDLILTGTPGGVGM 257
           +    + L + C +NG +KQ S+T  ++  +  L+  ++S+MTL PGD+I TGTP GVG 
Sbjct: 156 D---PMNLNIECRVNGEIKQKSNTKNMIFDVYELVEFVASIMTLYPGDIISTGTPPGVG- 211

Query: 258 YRQPPEYLQPGDVLTSEIEKIG 279
                  L+ GDV+  EIE IG
Sbjct: 212 ------ELKAGDVVECEIEGIG 227


>UniRef50_O53242 Cluster: POSSIBLE
           2-HYDROXYHEPTA-2,4-DIENE-1,7-DIOATE ISOMERASE; n=41;
           Bacteria|Rep: POSSIBLE
           2-HYDROXYHEPTA-2,4-DIENE-1,7-DIOATE ISOMERASE -
           Mycobacterium tuberculosis
          Length = 239

 Score =  165 bits (400), Expect = 2e-39
 Identities = 87/217 (40%), Positives = 131/217 (60%), Gaps = 11/217 (5%)

Query: 63  PLSSVTLTAPIHGVDKILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRIRT 122
           PL+ V L API    K++C+G NY DH  E    PP  P++F K ++ IIGP+ P+R+  
Sbjct: 22  PLADVRLLAPILA-SKVVCVGKNYADHIAEMGGRPPADPVIFLKPNTAIIGPNTPIRLPA 80

Query: 123 DVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLLGKS 182
           + +  V +E EL +V+GR    V    A+ ++ GYT+  D+SARD Q+    GQ+   K 
Sbjct: 81  NASP-VHFEGELAIVIGRACKDVPAAQAVDNILGYTIGNDVSARDQQQSD--GQWTRAKG 137

Query: 183 MDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLV 242
            DTFCP+GP ++T        +L +   +NG +KQ + T+ ++H I +++  IS++MTL+
Sbjct: 138 HDTFCPVGPWIVTDLAPFDPADLELRTVVNGDVKQHARTSLMIHDIGAIVEWISAIMTLL 197

Query: 243 PGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIG 279
           PGDLILTGTP GVG        ++ GD ++  IE IG
Sbjct: 198 PGDLILTGTPAGVGP-------IEDGDTVSITIEGIG 227


>UniRef50_Q2UMF8 Cluster: Predicted fumarylacetoacetate hydralase;
           n=8; Pezizomycotina|Rep: Predicted fumarylacetoacetate
           hydralase - Aspergillus oryzae
          Length = 289

 Score =  164 bits (398), Expect = 3e-39
 Identities = 85/216 (39%), Positives = 126/216 (58%), Gaps = 4/216 (1%)

Query: 69  LTAPIHGVD--KILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGP--DQPVRIRTDV 124
           L AP+   D   + C+GLNY+ H +E NL  P  P++F K  + I GP  D P+      
Sbjct: 60  LLAPLAREDIATVRCLGLNYEQHARESNLPIPKYPVLFYKPITAITGPYDDIPICSMAQD 119

Query: 125 TKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLLGKSMD 184
            + +D+E EL +V+G++A  + EE AL +V GY V  DIS RDWQ ++  GQ+ LGK  D
Sbjct: 120 VEGLDYECELVLVIGKQAKNIPEEQALDYVLGYAVGNDISHRDWQLKRGGGQWGLGKGFD 179

Query: 185 TFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPG 244
            + P GP ++++  +     L +S  +NG   QSSST  ++  +   +  +S   TL+PG
Sbjct: 180 GWAPFGPGIVSTKLIRNPNALNISTKVNGQTVQSSSTKDMIFGVAQTVSFLSQGTTLLPG 239

Query: 245 DLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIGA 280
           DLI TGTP GVGM R+P  +L  GD +   +E +G+
Sbjct: 240 DLIFTGTPQGVGMGRKPAAWLTNGDQVEVSLEDVGS 275


>UniRef50_A3IC16 Cluster: Fumarylacetoacetate hydrolase family
           protein; n=1; Bacillus sp. B14905|Rep:
           Fumarylacetoacetate hydrolase family protein - Bacillus
           sp. B14905
          Length = 314

 Score =  163 bits (397), Expect = 4e-39
 Identities = 84/211 (39%), Positives = 128/211 (60%), Gaps = 4/211 (1%)

Query: 71  APIHGVDK-ILCIGLNYKDHCQEQNLTPPPVP-MVFSKFSSTIIGPDQPVRIRTDVTKKV 128
           +PI    K I+CIG NY +H +E      P   MVF+K  + I    Q + I  D++ K+
Sbjct: 85  SPIPRTPKNIMCIGKNYNEHAKEMGAEAAPKELMVFTKSPTAIAADGQTLSIHADLSSKM 144

Query: 129 DWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLLGKSMDTFCP 188
           D+E EL +V+G+    + +  A  +V GYT+A DI+ARD Q++    QF LGKS++  CP
Sbjct: 145 DYEGELAIVIGKRGKNIPKNLAYDYVFGYTIANDITARDLQEKHK--QFFLGKSLEGTCP 202

Query: 189 LGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPGDLIL 248
           LGP ++T DE+    +L V   +N  ++Q+ ST  ++ S+ +L+  +S  +TL PGD+IL
Sbjct: 203 LGPYLVTKDEIPNPQDLTVVTKVNDEVRQNGSTKDMMFSVETLVSILSQHVTLEPGDVIL 262

Query: 249 TGTPGGVGMYRQPPEYLQPGDVLTSEIEKIG 279
           TGTP GVG    PP++L+ GD +   I+ IG
Sbjct: 263 TGTPAGVGKGMNPPQFLKAGDTVKVSIQGIG 293


>UniRef50_Q0C030 Cluster: Fumarylacetoacetate hydrolase family
           protein; n=1; Hyphomonas neptunium ATCC 15444|Rep:
           Fumarylacetoacetate hydrolase family protein -
           Hyphomonas neptunium (strain ATCC 15444)
          Length = 281

 Score =  163 bits (396), Expect = 5e-39
 Identities = 82/232 (35%), Positives = 137/232 (59%), Gaps = 5/232 (2%)

Query: 48  LEKVKKLKSTKPATIPLSSVTLTAPIHGVDKILCIGLNYKDHCQEQNLTPPPVPMVFSKF 107
           L ++ ++  +   T+PL  V L  P   + K++C+GLNYK+H  E +   PP P +F+K 
Sbjct: 45  LSQLGEIADSAGETLPLDQVGLLMPSEPLSKLVCLGLNYKNHVDETHNDLPPNPALFTKV 104

Query: 108 SSTIIGPDQPVRIRTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARD 167
           + +++   + V +R  V+++ D+E E+CVV+G+    +  E AL HV GYT+  D S RD
Sbjct: 105 ADSLVPHGEAV-LRPKVSEQFDYEGEICVVIGKGGRHISRETALDHVFGYTIMLDGSVRD 163

Query: 168 WQKEKNMGQFLLGKSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHS 227
           +QK         GK+      LGP ++T+DE+     +++   LNG   QS++   +++ 
Sbjct: 164 YQKHSVSA----GKNFWRSGALGPWIVTADEIPDPSVMKLETRLNGETVQSTTADLMLYD 219

Query: 228 IPSLLHRISSVMTLVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIG 279
           IP+ +  +S    L PGD+I TGTPGGVG  R+PP +++ GDV+  ++ +IG
Sbjct: 220 IPTAIAYVSQWTPLAPGDVIATGTPGGVGARRKPPLWMKAGDVIEVDVSQIG 271


>UniRef50_Q0SJB3 Cluster: Possible fumarylacetoacetate hydrolase;
           n=2; Rhodococcus|Rep: Possible fumarylacetoacetate
           hydrolase - Rhodococcus sp. (strain RHA1)
          Length = 296

 Score =  163 bits (395), Expect = 6e-39
 Identities = 91/221 (41%), Positives = 124/221 (56%), Gaps = 4/221 (1%)

Query: 60  ATIPLSSVTLTAPIHGVDKILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVR 119
           A  P+    L AP+    +I  IG+NY DH +E  LT P  P VF+KF ++I GP   + 
Sbjct: 54  AGAPVVESELGAPVPRPGQIFAIGVNYADHVEESGLTLPDAPFVFTKFPASITGPYDTIE 113

Query: 120 IRTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKE-KNMGQFL 178
               +   VD+EVEL  V+G+EA  V   +  ++VAG T+ QD+S RD Q       QF 
Sbjct: 114 HPGGL---VDFEVELVAVIGKEARHVPVAEGWEYVAGLTLGQDLSERDLQLSGPPPQQFT 170

Query: 179 LGKSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSV 238
           LGKS   F P+GP ++T DE     ++ VS  L+G L Q+S T  L+  IP L+  +SS+
Sbjct: 171 LGKSFAGFAPIGPVLVTPDEFADPDDIEVSTILSGELMQNSRTRHLIFPIPVLVSYLSSI 230

Query: 239 MTLVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIG 279
           + L PGDLI TGTP G+G  R P   +   D L S  + IG
Sbjct: 231 LPLRPGDLIFTGTPSGIGFTRDPKRLIGVDDELVSRADTIG 271


>UniRef50_Q0C3X7 Cluster: Fumarylacetoacetate hydrolase family
           protein; n=1; Hyphomonas neptunium ATCC 15444|Rep:
           Fumarylacetoacetate hydrolase family protein -
           Hyphomonas neptunium (strain ATCC 15444)
          Length = 277

 Score =  163 bits (395), Expect = 6e-39
 Identities = 99/283 (34%), Positives = 153/283 (54%), Gaps = 26/283 (9%)

Query: 1   MKLVQFSYKDSPKNIRVGYLEGDDIVDINKADSSLPTTLLQILRNGDLEKVKKLKSTKPA 60
           M+LV+F   ++  ++R G+LEGD +V +   DS      +  L   +          K A
Sbjct: 1   MRLVRF---EAEGHVRFGHLEGDTVVPV-AGDS-----FIDALEGRE----------KGA 41

Query: 61  TIPLSSVTLTAPIHGVDKILCIGLNYKDHCQEQ----NLTPPPVPMVFSKFSSTIIGPDQ 116
            + LS V L AP+    KIL IG+NY  H  E     N   P V   F+K ++ + GP  
Sbjct: 42  PLALSVVRLLAPVPRPRKILGIGVNYAAHAAESVSFINTAKPEVQKWFNKQATAVNGPYD 101

Query: 117 PVRIRTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQ 176
           PV +   V+ ++D+E EL  V+G+    V  E A++ VAG+ +  D S RDWQK      
Sbjct: 102 PVHLPR-VSSQLDYEGELVAVIGKHGRHVPAERAMEIVAGFCIGCDYSVRDWQKASQT-- 158

Query: 177 FLLGKSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRIS 236
            ++GK  DT  P GP ++T DE+G   +L +   +NG L+QS     ++H + + +  ++
Sbjct: 159 MIMGKGFDTHAPFGPALVTPDELGDISDLEIRSFVNGELRQSGRPRDMIHDVGAQIAHLT 218

Query: 237 SVMTLVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIG 279
           +  TL PGD+I TGTP GVG    PP++L+ GD +  EI+++G
Sbjct: 219 AAFTLEPGDVIFTGTPAGVGAGFDPPKWLKAGDRVRIEIDRLG 261


>UniRef50_A1SD71 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate
           decarboxylase; n=5; Bacteria|Rep:
           5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase -
           Nocardioides sp. (strain BAA-499 / JS614)
          Length = 284

 Score =  162 bits (394), Expect = 8e-39
 Identities = 86/221 (38%), Positives = 128/221 (57%), Gaps = 3/221 (1%)

Query: 60  ATIPLSSVTLTAPIHGVDKILCIGLNYKDHCQEQNL-TPPPVPMVFSKFSSTIIGPDQPV 118
           A + +    L AP     + + IGLNY++H  E     P  +P VF+KF+S+I GP   V
Sbjct: 59  ADVVIDPDLLGAPSPRPTQAIAIGLNYEEHAHETGYQVPTQLPPVFAKFASSITGPRGLV 118

Query: 119 RIRTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFL 178
            +        DWEVE+  V+GR A  +  ++A  HVAG TV QD+S R  Q      QF 
Sbjct: 119 DLPPG--GHTDWEVEVVAVIGRTAHRISPDEAWGHVAGLTVGQDLSERISQMAGPAPQFG 176

Query: 179 LGKSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSV 238
           L KS   F P+GP ++T +E+    +L + C+++G   Q   T++L+ SIP  +  +S V
Sbjct: 177 LAKSFPGFSPMGPWLVTPEELADPDDLALGCAIDGETVQDGRTSKLIFSIPRSIAALSQV 236

Query: 239 MTLVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIG 279
           +TL+PGD++ TGTP GVG+ R P  +L+PG+ L + +E IG
Sbjct: 237 LTLLPGDVVFTGTPDGVGLGRSPQRFLRPGETLRTWVEGIG 277


>UniRef50_A5VAQ6 Cluster: 5-carboxymethyl-2-hydroxymuconate
           Delta-isomerase; n=1; Sphingomonas wittichii RW1|Rep:
           5-carboxymethyl-2-hydroxymuconate Delta-isomerase -
           Sphingomonas wittichii RW1
          Length = 282

 Score =  162 bits (393), Expect = 1e-38
 Identities = 85/220 (38%), Positives = 123/220 (55%), Gaps = 4/220 (1%)

Query: 60  ATIPLSSVTLTAPIHGVDKILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVR 119
           A IPL  V L  PI   DK+LC+  N+++  +E     P  P+VF++F+++  G  QP+ 
Sbjct: 54  ADIPLDQVRLLPPIPNPDKVLCVATNFREPAREGK-PEPEYPLVFTRFANSFTGHGQPLA 112

Query: 120 IRTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLL 179
            + D ++  D+E EL VV+G+    +   +A+ HV GY    D S RDWQK     QF  
Sbjct: 113 -KPDRSEAYDFEGELAVVIGKGGHRIPASEAMAHVGGYCCLNDGSVRDWQKHST--QFTP 169

Query: 180 GKSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVM 239
           GK+       GP ++T+DE+     L +   +NGV+KQ     +++  IP L+   S+  
Sbjct: 170 GKNFHRSGSFGPWIVTADEIPDPTVLTLQTRVNGVVKQRIGIDRMIFDIPWLIAYFSTFT 229

Query: 240 TLVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIG 279
            LVPGD+I TGTP G G  R PPEYL  GD +  EI +IG
Sbjct: 230 PLVPGDVIATGTPSGFGSSRTPPEYLSIGDAIEVEISEIG 269


>UniRef50_Q11EA1 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=5;
           Proteobacteria|Rep: Fumarylacetoacetate (FAA) hydrolase
           - Mesorhizobium sp. (strain BNC1)
          Length = 287

 Score =  161 bits (391), Expect = 2e-38
 Identities = 94/269 (34%), Positives = 149/269 (55%), Gaps = 10/269 (3%)

Query: 16  RVGYLEGDDIVDINKADSSLPTTLLQILRNG--DLEKVKKLKSTKPATIPLSSVTLTAPI 73
           R+G +E  ++VD+   +  LP  ++ IL  G   LE V+ L + +   + L+ V L API
Sbjct: 13  RIGLVERGEVVDLLSGNPRLPNDMVAILEGGAETLEAVR-LAAGRANRLALNEVQLNAPI 71

Query: 74  HGVDKILCIGLNYKDHCQE---QNLTPPPVPMVFSKFSSTIIGPDQPVRIRTDVTKKVDW 130
               K L +GL++K    E   + +  P   + F+K  + I GP  PV +   V+ ++D+
Sbjct: 72  TRPRKFLGLGLSFKSSADEFRAKGVAIPEHQVWFNKQVTAINGPYDPVHMPR-VSSELDY 130

Query: 131 EVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLLGKSMDTFCPLG 190
           E EL +V+G+     R  DA + +AG+ V  D S RDWQ+        LGKS DT  P+G
Sbjct: 131 EGELALVIGKRIRHARTSDAEKIIAGFLVCNDFSVRDWQRRSPTAT--LGKSFDTHGPIG 188

Query: 191 PCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPGDLILTG 250
           P + T DEV  +  LR+   ++G L+Q  +T  L+++   ++  +S+  TL PGD++ TG
Sbjct: 189 PWLTTFDEVDPS-SLRIRTWVDGELRQDGNTDDLLYTFGEMIAELSTAFTLEPGDILATG 247

Query: 251 TPGGVGMYRQPPEYLQPGDVLTSEIEKIG 279
           +P G G Y +PP YL+ G  +  EIE +G
Sbjct: 248 SPTGAGQYMRPPTYLKTGQTVRVEIEGLG 276


>UniRef50_Q9VU50 Cluster: CG11251-PA; n=1; Drosophila
           melanogaster|Rep: CG11251-PA - Drosophila melanogaster
           (Fruit fly)
          Length = 338

 Score =  161 bits (390), Expect = 2e-38
 Identities = 84/211 (39%), Positives = 122/211 (57%), Gaps = 7/211 (3%)

Query: 69  LTAPIHGVDKILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRIRTDVTKKV 128
           L  PI    KI+ +  NY D+C EQ+++ P  P    KF+S+I G    +R  +   K +
Sbjct: 124 LLPPIDSPSKIIGVDCNYVDNCDEQHISIPREPSFHVKFASSITGALDNIRAHSSA-KHI 182

Query: 129 DWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLLGKSMDTFCP 188
           D+  +L VV+G+    V  ++AL HV G+ V QDI ARDW         L G SMDTF P
Sbjct: 183 DYGCQLAVVMGKRCREVSPKEALNHVFGFMVVQDIVARDWNVP------LGGHSMDTFLP 236

Query: 189 LGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPGDLIL 248
           LGP ++    V     L +   +NG  +Q+ +T  ++  I  L+HR+S  +TL PGD+IL
Sbjct: 237 LGPTIVHRCHVPDLNNLWIKTIINGEERQTGNTRNMIFKIDFLIHRLSQYLTLCPGDIIL 296

Query: 249 TGTPGGVGMYRQPPEYLQPGDVLTSEIEKIG 279
           TGTP G G +R P  +L+PGD++ SEI+ +G
Sbjct: 297 TGTPAGSGAFRHPSCFLKPGDLIESEIQNLG 327


>UniRef50_O27551 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate
           isomerase; n=4; Archaea|Rep:
           2-hydroxyhepta-2,4-diene-1,7-dioate isomerase -
           Methanobacterium thermoautotrophicum
          Length = 260

 Score =  161 bits (390), Expect = 2e-38
 Identities = 89/224 (39%), Positives = 130/224 (58%), Gaps = 14/224 (6%)

Query: 64  LSSVTLTAPIHGVDKILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRIRTD 123
           L  V +  P+    K++C+GLNY+DH  E  +  P  P++F K  +T+IG    V I  +
Sbjct: 46  LDDVRILPPV-SPSKVVCVGLNYRDHAAELGMDIPDEPIIFLKPPTTVIGSGDTV-IYPE 103

Query: 124 VTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLLGKSM 183
           ++ +VD+EVEL  VV   A  V    A + +AGYTV  D++ARD Q+    GQ+   KS 
Sbjct: 104 MSSEVDYEVELAAVVSERARRVDSSAASEFIAGYTVLNDVTARDLQRRD--GQWTRAKSF 161

Query: 184 DTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVP 243
           DTFCP+GP + T         L +S  LNG ++QSS+T+ ++ ++  LL  IS VMTL P
Sbjct: 162 DTFCPIGPVIETDVTPD---NLDISLKLNGEVRQSSNTSNMIFTVHELLEFISHVMTLEP 218

Query: 244 GDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIGAFDVRIEK 287
           GD+I TGTP GVG        + PGD + + +E +G    R+E+
Sbjct: 219 GDVIATGTPPGVGQ-------MVPGDTVRATVEGVGTLVNRVER 255


>UniRef50_Q8YDN8 Cluster: 2-HYDROXYHEPTA-2,4-DIENE-1,7-DIOATE
           ISOMERASE / 5-CARBOXYMETHYL-2-OXO- HEX-3-ENE-1,7-DIOATE
           DECARBOXYLASE; n=19; Proteobacteria|Rep:
           2-HYDROXYHEPTA-2,4-DIENE-1,7-DIOATE ISOMERASE /
           5-CARBOXYMETHYL-2-OXO- HEX-3-ENE-1,7-DIOATE
           DECARBOXYLASE - Brucella melitensis
          Length = 311

 Score =  160 bits (388), Expect = 4e-38
 Identities = 82/264 (31%), Positives = 148/264 (56%), Gaps = 4/264 (1%)

Query: 18  GYLEGDDIVDINKADSSLPTTLLQILRNGDLEKVKKLKSTKPATIPLSSVTLTAPIHGVD 77
           G L+ D IVD++    S   TL +++  G L ++ +  +   A +PLSS+T   PI    
Sbjct: 39  GVLKEDGIVDLSARHGSRWPTLREVIEAGVLAQLAQEAAGLAADVPLSSITYEIPIPSPG 98

Query: 78  KILCIGLNYKDHCQE--QNLTPPPVPMVFSKFSSTIIGPDQPVRIRTDVTKKVDWEVELC 135
           KI+C+G+N+ D  +E       P  P +F +F  +  G ++P+ +R   + ++D+E E+ 
Sbjct: 99  KIICVGVNFPDRNEEYKDGQAAPANPSLFVRFPRSFTGHERPL-MRPPESPQLDYEGEIA 157

Query: 136 VVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLLGKSMDTFCPLGPCVLT 195
           +V+G+    + E+DAL H+A  T+  + + RDW +         GK+ D    +GP ++ 
Sbjct: 158 IVIGKGGRRIAEKDALDHIAALTLCNEGTIRDWVRHAKFN-VTQGKNFDATGSIGPWLVP 216

Query: 196 SDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPGDLILTGTPGGV 255
             +     +++++  +NG ++Q   T++++ S   +++ +S+  TLVPGD+I+ GTP G 
Sbjct: 217 YTDESQIADIQLTTRVNGEVRQQDRTSRMIFSFRKIINYVSTFTTLVPGDVIVCGTPTGA 276

Query: 256 GMYRQPPEYLQPGDVLTSEIEKIG 279
           G    PP +L+PGDV+  E E IG
Sbjct: 277 GARFDPPIWLKPGDVVEVEAEGIG 300


>UniRef50_A3LSP4 Cluster: Degradation of aromatic compounds; n=9;
           Ascomycota|Rep: Degradation of aromatic compounds -
           Pichia stipitis (Yeast)
          Length = 293

 Score =  159 bits (387), Expect = 6e-38
 Identities = 80/219 (36%), Positives = 127/219 (57%), Gaps = 7/219 (3%)

Query: 68  TLTAPI--HGVDKILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRIRTDVT 125
           TL  P+    V  + C+GLN+  H QE   TPPP P +F K S ++    + + I     
Sbjct: 66  TLLGPLTPDDVPMVKCVGLNFMKHIQEGGRTPPPFPSIFYKTSFSVADFGEDIPIPKIAQ 125

Query: 126 KKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEK----NMGQFLLGK 181
            K D+E ELC+V+G+    ++EE+AL +VAGY    D+S+R+WQK+     ++ Q+   K
Sbjct: 126 SKCDYEGELCIVIGKTGKNIKEEEALSYVAGYVTGNDVSSRNWQKDPEFAGSVPQWCFSK 185

Query: 182 SMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTL 241
           S D + PLGP +++   +     L +  ++NG ++Q ++T  L+  +P ++  IS   TL
Sbjct: 186 SFDKYAPLGPALVSPQVIQNPGNLSLQTTVNGEIRQDANTDDLLFGVPRIISFISQSTTL 245

Query: 242 VPGDLILTGTPGGVGMYRQP-PEYLQPGDVLTSEIEKIG 279
             G +I+TGTP GV +  +P P YLQ GDV+   I++IG
Sbjct: 246 EMGTVIMTGTPSGVALGMKPTPVYLQNGDVVEVAIDQIG 284


>UniRef50_Q6M0X4 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate
           decarboxylase; n=7; cellular organisms|Rep:
           5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase -
           Methanococcus maripaludis
          Length = 202

 Score =  159 bits (387), Expect = 6e-38
 Identities = 81/202 (40%), Positives = 130/202 (64%), Gaps = 13/202 (6%)

Query: 78  KILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRIRTDVTKKVDWEVELCVV 137
           KI+C GLNYKDH +E  +  P  P++F K +S+II  ++ ++I    +++VD+E EL +V
Sbjct: 7   KIVCAGLNYKDHAEELKMKLPKEPVIFLKPTSSIIYNEEAIKI-PKASERVDYEAELAIV 65

Query: 138 VGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLLGKSMDTFCPLGPCVLTSD 197
           +G+    V++ED   ++ G+T+  D++ARD Q EK+ GQ+   KS DTF P+GP +++  
Sbjct: 66  IGKTCKSVKKEDVKNYIKGFTILNDVTARDLQ-EKD-GQWTRAKSFDTFSPIGPKIVSGI 123

Query: 198 EVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPGDLILTGTPGGVGM 257
           +   A  L++   +NG +KQ S+T  ++ S+  L+  +SS+MTL PGD+I TGTP G+G 
Sbjct: 124 D---ANNLKIQLRVNGKIKQDSNTNNMIFSVEELVEFVSSIMTLYPGDIISTGTPPGIGK 180

Query: 258 YRQPPEYLQPGDVLTSEIEKIG 279
                  L+ GD++  EIE IG
Sbjct: 181 -------LEKGDIVEIEIENIG 195


>UniRef50_UPI00015C5CCD Cluster: hypothetical protein CKO_03358;
           n=1; Citrobacter koseri ATCC BAA-895|Rep: hypothetical
           protein CKO_03358 - Citrobacter koseri ATCC BAA-895
          Length = 295

 Score =  158 bits (383), Expect = 2e-37
 Identities = 90/279 (32%), Positives = 146/279 (52%), Gaps = 10/279 (3%)

Query: 1   MKLVQFSYKDSPKNIRVGYLEGDDIVDINKADSSLPTTLLQILRNGDLEKVKKLKSTKPA 60
           MKL  F Y+ +      G +    ++D+          L  +L+   LE+ ++     P 
Sbjct: 9   MKLASFLYQGTRS---YGIVTAGGVIDLGNRIGDQYRDLKALLQGDGLEQARRFAQA-PV 64

Query: 61  TIPLSSVTLTAPIHGVDKILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRI 120
            + + ++T    I   +KILC+G+NY +  QE +    P P +F +F+ +  G + PV +
Sbjct: 65  DLKMDAITFLPVIERPEKILCVGMNYAEKRQEFD-QHDPAPTLFVRFADSQTGHNMPV-L 122

Query: 121 RTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLLG 180
           +   + + D+E EL V++G     +  + AL HVAGY+   D SARDWQ       F  G
Sbjct: 123 KPRHSHEFDYEGELAVIIGNGGENISRDHALDHVAGYSCYMDGSARDWQHS----WFTAG 178

Query: 181 KSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMT 240
           K+       GP ++T+DE+    +L +   LNG + Q  +T+ ++H +  L+  IS+   
Sbjct: 179 KNWRQTGAFGPWMVTADEIPDPHQLAIRTWLNGRMVQEDNTSSMIHKVAELIEYISTFTR 238

Query: 241 LVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIG 279
           L  GD+I+TG+PGGVG  R PP ++Q GD +  EIE IG
Sbjct: 239 LNSGDVIITGSPGGVGKKRNPPLFMQEGDRIEVEIEHIG 277


>UniRef50_Q0V440 Cluster: Putative uncharacterized protein; n=1;
           Phaeosphaeria nodorum|Rep: Putative uncharacterized
           protein - Phaeosphaeria nodorum (Septoria nodorum)
          Length = 286

 Score =  158 bits (383), Expect = 2e-37
 Identities = 77/207 (37%), Positives = 121/207 (58%), Gaps = 2/207 (0%)

Query: 76  VDKILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRIRTDVTKKVDWEVELC 135
           V+ ILC+GLNY+ H +E NL  P  P +F K S  + GP + V I  D    +D+E EL 
Sbjct: 67  VNVILCVGLNYRRHAEECNLQIPENPAIFMKPSDALAGPLEDVPIHKDCQSMLDYEGELT 126

Query: 136 VVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNM--GQFLLGKSMDTFCPLGPCV 193
           +V+G++   V   +   +V GYTV  D+SAR++Q   N+  GQF   KS D FCP+GPC+
Sbjct: 127 IVIGKDCKNVSAANFQDYVLGYTVGNDVSARNYQLPANVSGGQFGYAKSFDKFCPIGPCI 186

Query: 194 LTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPGDLILTGTPG 253
            ++  +    +L     +NG  +Q + T  ++++I  ++  +S   TL  G  ILTGTP 
Sbjct: 187 ASTKVIPDPQKLTYWTKVNGEKRQETGTDDMIYTIGQVIEHLSRGTTLRAGTAILTGTPS 246

Query: 254 GVGMYRQPPEYLQPGDVLTSEIEKIGA 280
           GVG++ +P  +L+ GD +   ++ IG+
Sbjct: 247 GVGLFMEPKNFLKDGDEVEIYVDGIGS 273


>UniRef50_Q46S57 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate
           decarboxylase; n=4; Burkholderiales|Rep:
           5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase -
           Ralstonia eutropha (strain JMP134) (Alcaligenes
           eutrophus)
          Length = 284

 Score =  157 bits (381), Expect = 3e-37
 Identities = 83/216 (38%), Positives = 130/216 (60%), Gaps = 4/216 (1%)

Query: 65  SSVTLTAPIHGVDKILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRIRTDV 124
           +++T   P+    KILC+GLNY DH +E     P  P +F +  ++++G D  + +R   
Sbjct: 60  AALTWLPPVISPRKILCVGLNYADHTKESPYEQPDYPTLFLRVPTSMVGHDCAI-VRPLA 118

Query: 125 TKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLLGKSMD 184
           +  +D+E EL VV+G+    +  EDAL HV GY+V  D S R++Q +    Q+ +GK+ D
Sbjct: 119 SDTLDYEGELAVVIGKGGKHIAREDALSHVFGYSVFNDGSVREYQFKSP--QWTVGKNFD 176

Query: 185 TFCPLGPCVLTSDEVG-AAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVP 243
                GP V+T+DE+   A  LR+   LNG + QS+ST+ +++ + SL+  IS  +TL P
Sbjct: 177 ATGGFGPYVVTADELPPGATGLRLETRLNGQVVQSASTSDMLYDVASLIAIISEAITLEP 236

Query: 244 GDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIG 279
           GD+I+ GTP G+G  R+P   ++ GDV    IE+IG
Sbjct: 237 GDVIVAGTPSGIGWAREPKLLMRHGDVCEVSIERIG 272


>UniRef50_A0HII6 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=2;
           Proteobacteria|Rep: Fumarylacetoacetate (FAA) hydrolase
           - Comamonas testosteroni KF-1
          Length = 286

 Score =  157 bits (381), Expect = 3e-37
 Identities = 87/247 (35%), Positives = 132/247 (53%), Gaps = 8/247 (3%)

Query: 38  TLLQILRNGDLEKVKKLKSTKPATIPLSSVTLTAPIHGVDKILCIGLNYKDHCQE----- 92
           TL   + + D  +   L     A   L+ VT    I   +KI+C   NY DH QE     
Sbjct: 33  TLADFIASPDFARRDALTDGLAADAKLADVTFLPVIPRPEKIVCAVRNYMDHHQEVLAAG 92

Query: 93  QNLTPPPVPMVFSKFSSTIIGPDQPVRIRTDVTKKVDWEVELCVVVGREASCVREEDALQ 152
                   P +F +   +      P+ +R  V+  +DWE EL V++G+    + E DA +
Sbjct: 93  MQRELSEEPPIFLRVWRSQTAHQGPI-VRPHVSDSLDWEGELAVIIGQGGRDIAEADAWE 151

Query: 153 HVAGYTVAQDISARDWQKEKNMGQFLLGKSMDTFCPLGPCVLTSDEVGAAVELRVSCSLN 212
           H+AGY+   D S R+WQ      Q   GK+ ++    GP ++T+DE+    EL++   LN
Sbjct: 152 HIAGYSCYNDASVREWQFHAK--QIASGKNFESTGAFGPWMVTADEISPGRELKLETRLN 209

Query: 213 GVLKQSSSTAQLVHSIPSLLHRISSVMTLVPGDLILTGTPGGVGMYRQPPEYLQPGDVLT 272
           G + QSS T  ++ SIP L+   S++ TLVPGD+I+TGTP GVG  ++P ++++ GDV+ 
Sbjct: 210 GAVVQSSHTGHMIFSIPRLIAYASTIFTLVPGDVIITGTPAGVGWSKKPQQFMKAGDVVE 269

Query: 273 SEIEKIG 279
            EIE IG
Sbjct: 270 VEIEAIG 276


>UniRef50_Q4L4Y4 Cluster: Uncharacterized protein SH1982; n=17;
           Staphylococcus|Rep: Uncharacterized protein SH1982 -
           Staphylococcus haemolyticus (strain JCSC1435)
          Length = 301

 Score =  157 bits (381), Expect = 3e-37
 Identities = 94/304 (30%), Positives = 160/304 (52%), Gaps = 21/304 (6%)

Query: 1   MKLVQFSYKDSPKNIRVGYLEGDDIVDINKADSSL------PTTLLQILR-NGDLEKVKK 53
           MK + F+YKD+ ++  V     D + D+ K  +        P TLL+ L+ N  L+  ++
Sbjct: 1   MKFLSFNYKDA-ESYGVKVKRKDAVWDLKKVFAEFGEGDFHPQTLLEGLQQNQTLDFQEQ 59

Query: 54  LKSTKPAT----------IPLSSVTLTAPIHGVDKILCIGLNYKDHCQEQNLTPPPVPMV 103
           ++    A           I  + +    P+   + ++  G NY+DH  E N     +  V
Sbjct: 60  VRKAVVAAEDSGKADEFKIAFNDIEFLPPVTPPNNVIAFGRNYQDHASELNHEVQRL-YV 118

Query: 104 FSKFSSTIIGPDQPVRIRTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDI 163
           F+K +S++ G +  +    D+T ++D+E EL +V+G+    + +  AL ++ GYT+  DI
Sbjct: 119 FTKAASSLTGDESTIPNHKDITDQLDYEGELGIVIGKSGEKIPKALALDYIYGYTIINDI 178

Query: 164 SARDWQKEKNMGQFLLGKSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQ 223
           + R  Q E++  Q  L KS+   CP+GP ++T DE+     + +   +N  ++Q  +T+Q
Sbjct: 179 TDRKAQNEQD--QAFLSKSLTGGCPMGPYIVTKDELPTPENVNIVTKVNNDIRQDGNTSQ 236

Query: 224 LVHSIPSLLHRISSVMTLVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIGAFDV 283
           +++ I  L+  IS  + L PGD+I TGTP GVG   QPP++LQPGD +   I+ IG    
Sbjct: 237 MINKIDDLIEEISKYVALHPGDIIATGTPAGVGAGLQPPQFLQPGDEVKVTIDNIGTLTT 296

Query: 284 RIEK 287
            I K
Sbjct: 297 YIAK 300


>UniRef50_Q8Y512 Cluster: Lmo2266 protein; n=13; Listeria|Rep:
           Lmo2266 protein - Listeria monocytogenes
          Length = 282

 Score =  157 bits (380), Expect = 4e-37
 Identities = 93/290 (32%), Positives = 158/290 (54%), Gaps = 12/290 (4%)

Query: 1   MKLVQFSYKDSPKNIRVGYLEGDD-IVDINKADSSLPTTLLQILRNGDLEKVKKLKSTKP 59
           MK + + Y+    ++  G L  ++ I+      S+ P TLL  ++   L  V +L     
Sbjct: 1   MKWLSYLYEG---DLAYGILTPENKIIPAGTIFSNPPATLLDFIKEKPL--VPELTGID- 54

Query: 60  ATIPLSSVTLTAPIHGVDKILCIGLNYKDHCQEQNLTP--PPVPMVFSKFSSTIIGPDQP 117
             I L+ V +  P    + I+ IG NY +H  E       P   +VF+K +++++  +  
Sbjct: 55  GHIDLAEVEIQVPFVPPNNIIAIGKNYYNHVLEMGSKEDVPEHILVFTKSANSLLPHNGN 114

Query: 118 VRIRTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQF 177
           + +  ++T ++D+E EL V++G +   + E++AL  + G+T+  DI+ARD QK+    QF
Sbjct: 115 IELHQNITGQLDYEGELAVIIGEKVRDISEQEALSAIFGFTILNDITARDLQKKHK--QF 172

Query: 178 LLGKSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISS 237
            LGKS+D  CP+GP VL ++     V   +   +NG ++QS ST + +  +  ++  +S 
Sbjct: 173 YLGKSLDASCPIGPFVLENNANKEPV-FHIETKVNGEVRQSDSTDKFIFGLARIISDLSK 231

Query: 238 VMTLVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIGAFDVRIEK 287
             TL+PGD+I TGTP GVG    PP +LQ GD++   I+KIG    ++ K
Sbjct: 232 GHTLLPGDIIATGTPSGVGNGMTPPTFLQDGDIIEITIDKIGTLTNKVRK 281


>UniRef50_A0QV79 Cluster: Fumarylacetoacetate hydrolase family
           protein; n=1; Mycobacterium smegmatis str. MC2 155|Rep:
           Fumarylacetoacetate hydrolase family protein -
           Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155)
          Length = 285

 Score =  157 bits (380), Expect = 4e-37
 Identities = 87/223 (39%), Positives = 125/223 (56%), Gaps = 6/223 (2%)

Query: 60  ATIPLSSVTLTAPIHGVDKILCIGLNYKDHCQEQNLTPPPVP---MVFSKFSSTIIGPDQ 116
           A +P   VTL  P+    K++CIGLNY  H  E +    P+P    +F+++ ST+     
Sbjct: 50  AVLPRDEVTLVPPVLPGAKVICIGLNYLKHVAEGSYGAEPLPEFPTLFARWPSTLTVDGA 109

Query: 117 PVRIRTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQ 176
            + + TD  + +DWE E+   VGRE SC   ++AL  V GY+   D++AR  + +K   Q
Sbjct: 110 QIPVPTD-EEGLDWEGEVVAWVGRELSCATADEALDAVVGYSTFNDVTAR--RAQKITSQ 166

Query: 177 FLLGKSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRIS 236
           ++LGK+ D   PLGP V   D       LRV   +NG   Q +ST ++V+++   L  IS
Sbjct: 167 WILGKNADRSGPLGPLVPAHDVGDLRDGLRVRTRVNGTTVQDASTDEMVYTVGETLAHIS 226

Query: 237 SVMTLVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIG 279
             +TL PGDL+ TGTP GVG  R P   L PGD +  E+EK+G
Sbjct: 227 RTLTLRPGDLLATGTPSGVGYARTPAWLLHPGDHVEVEVEKLG 269


>UniRef50_A5VE85 Cluster: 5-carboxymethyl-2-hydroxymuconate
           Delta-isomerase; n=2; Sphingomonas wittichii RW1|Rep:
           5-carboxymethyl-2-hydroxymuconate Delta-isomerase -
           Sphingomonas wittichii RW1
          Length = 356

 Score =  156 bits (379), Expect = 5e-37
 Identities = 83/215 (38%), Positives = 120/215 (55%), Gaps = 3/215 (1%)

Query: 65  SSVTLTAPIHGVDKILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRIRTDV 124
           SS+T   P+   DKI+ +G NY+ H  E     P  P +F +F S+ +G  QPV +   +
Sbjct: 127 SSLTFLPPVTDPDKIIAVGFNYRGHLIETGTPLPDYPSLFVRFPSSQVGHGQPV-VAPSL 185

Query: 125 TKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLLGKSMD 184
           + + D+E EL V++GR A  V E DA+ HV GY+   + S RD+Q      Q   GK+  
Sbjct: 186 SGEFDFEGELAVIIGRPAWRVAEADAMDHVVGYSCFAENSVRDYQAHAR--QVTAGKNFL 243

Query: 185 TFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPG 244
               +GP + T+DEVG    L ++  LNG + Q      L+ +IP L+  I+    L+PG
Sbjct: 244 ASGAIGPWLTTADEVGDPSTLELTTRLNGAVVQQDRLTSLIFTIPQLIAYITRFTRLLPG 303

Query: 245 DLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIG 279
           D+I TGTP GVG  R P  +L PGDVL  +I ++G
Sbjct: 304 DIISTGTPDGVGFLRDPKIWLAPGDVLEIDIPRVG 338


>UniRef50_A3TUH0 Cluster: Fumarylacetoacetate hydrolase family
           protein; n=1; Oceanicola batsensis HTCC2597|Rep:
           Fumarylacetoacetate hydrolase family protein -
           Oceanicola batsensis HTCC2597
          Length = 252

 Score =  156 bits (379), Expect = 5e-37
 Identities = 91/225 (40%), Positives = 129/225 (57%), Gaps = 16/225 (7%)

Query: 56  STKPATIPLSSVTLTAPIHGVDKILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPD 115
           ST    +PLS V L  P+    K++C+GLNYK H +E     P  PM+F    S +I PD
Sbjct: 34  STTEDRLPLSDVALLPPVEP-GKLVCVGLNYKRHAEESGAAIPEEPMLFMCAPSAVI-PD 91

Query: 116 QPVRIRTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMG 175
               +      ++D+E E+ +V+G++A  + E DA   + GYT+  D+S RD+QK+   G
Sbjct: 92  GGTILLDSQDARIDYEAEIAIVIGKQARNLPEADARSCIFGYTICNDVSNRDYQKKD--G 149

Query: 176 QFLLGKSMDTFCPLGPCVLTS-DEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHR 234
           QF   KS DT+ PLGP + T  D   AA+ LR     NG L+Q S+T+ ++ SI  ++  
Sbjct: 150 QFTRAKSFDTYKPLGPWIETGLDPDNAAISLRQ----NGELRQQSNTSDMIFSIDRIVAF 205

Query: 235 ISSVMTLVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIG 279
           +S +MTL PGD+I+TGTP GVG  R        GD +  EIE IG
Sbjct: 206 VSGIMTLNPGDVIITGTPEGVGPMRS-------GDRIEIEIEGIG 243


>UniRef50_Q46NJ4 Cluster: 5-carboxymethyl-2-hydroxymuconate
           delta-isomerase; n=6; Proteobacteria|Rep:
           5-carboxymethyl-2-hydroxymuconate delta-isomerase -
           Ralstonia eutropha (strain JMP134) (Alcaligenes
           eutrophus)
          Length = 292

 Score =  155 bits (377), Expect = 9e-37
 Identities = 93/284 (32%), Positives = 151/284 (53%), Gaps = 8/284 (2%)

Query: 1   MKLVQFSYKDSPK-NIRVGYLEGDDIVDINKADSSLPTTLLQILRNGD--LEKVKKLKST 57
           MKLV F   DS      VG+     +VD+++    +P+ +  +L  G   L + ++  + 
Sbjct: 1   MKLVTFRTSDSVSWGAVVGHDSASGVVDLSRRLPDVPS-VKSLLSGGASLLARAREALAG 59

Query: 58  KPATIPLSSVTLTAPIHGVDKILCIGLNYKDHCQE--QNLTPPPVPMVFSKFSSTIIGPD 115
                PLSSV L  P+ G +KI CIG+NY     E   N   P  P VF +  +++ G  
Sbjct: 60  VQVDHPLSSVQLLPPVLGPEKIFCIGVNYAHRNAEYKDNSDLPKYPSVFMRTPASLTGHG 119

Query: 116 QPVRIRTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMG 175
           QP+ +  + +K++D+E E+ +V+G+    + +EDA  H+AG T   + + RDW       
Sbjct: 120 QPLLLPPE-SKQLDYEGEIGIVIGKAGRRIAKEDAHTHIAGLTCINEGTIRDWLHHGKFN 178

Query: 176 QFLLGKSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRI 235
               GK+ D    +GP ++T+DE      + ++  +NG ++Q  +TA L+    SL+  +
Sbjct: 179 -VTQGKNFDASGAIGPWIVTADEFPDFDNIGLTTRVNGEVRQQDTTANLMFPFASLISYL 237

Query: 236 SSVMTLVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIG 279
           S   TL PGD+I TGTP G G+   PP +L PGDV+  E++ +G
Sbjct: 238 SQFATLNPGDIIATGTPIGAGVRFDPPRFLVPGDVVEVEVDGVG 281


>UniRef50_Q9HK55 Cluster: Probable 2-hydroxyhepta-2, 4-diene-1,
           7-dioate isomerase; n=1; Thermoplasma acidophilum|Rep:
           Probable 2-hydroxyhepta-2, 4-diene-1, 7-dioate isomerase
           - Thermoplasma acidophilum
          Length = 315

 Score =  155 bits (377), Expect = 9e-37
 Identities = 90/293 (30%), Positives = 155/293 (52%), Gaps = 16/293 (5%)

Query: 1   MKLVQFSYKDSPKN-IRVG-----YLEGDDIVDINKADSSLPTTLLQILRNGDLEKVKKL 54
           +K++ F  KD P   + +G     + E   I D+ K+       +       D++ + + 
Sbjct: 30  LKILNFLDKDGPAGGVLLGDTLYPFAELSKISDVFKSFQITDDVIASNADQNDIDMIVEE 89

Query: 55  KSTKPATIPLSSVTLTAPIHGVDKILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGP 114
             +K    P+++  + AP+    KILCIG+NY +H +E        P +F KF  +IIG 
Sbjct: 90  SKSKLRGRPIATTKILAPVLRSGKILCIGVNYMEHAKESRQKVMEHPTIFCKFQDSIIGN 149

Query: 115 DQPVRIRTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNM 174
              + +  D  K++D+E EL V++GR +           + GYT+  D+SARD Q   + 
Sbjct: 150 MDDITVPKDA-KQIDYEGELVVIIGRSSGTAESS-----IFGYTIGNDVSARDLQFRTS- 202

Query: 175 GQFLLGKSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHR 234
            Q+LLGK++ TF P+GP ++  +E+G A +L++   +NG ++Q+ +T+ ++  + +++  
Sbjct: 203 -QWLLGKALPTFAPIGPVIVGKNELGFARDLQIITRVNGTVRQNGNTSDMIFDVRAIVDY 261

Query: 235 ISSVMTLVPGDLILTGTPGGV--GMYRQPPEYLQPGDVLTSEIEKIGAFDVRI 285
           +S    L PGD+I TGTP GV  G+      +L+ GDV+   I  IG    RI
Sbjct: 262 LSGYFNLGPGDIIFTGTPEGVILGLPENERVWLKHGDVIDVSITGIGTLTNRI 314


>UniRef50_Q6L066 Cluster: Fumarylacetoacetate hydrolase family
           protein; n=1; Picrophilus torridus|Rep:
           Fumarylacetoacetate hydrolase family protein -
           Picrophilus torridus
          Length = 281

 Score =  155 bits (377), Expect = 9e-37
 Identities = 83/216 (38%), Positives = 128/216 (59%), Gaps = 4/216 (1%)

Query: 73  IHGVDKILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRIRTDVTKKVDWEV 132
           I   +KI+C+G NYK+H  E     P  P++FSKF++T+ G    + I  D +  +D+E 
Sbjct: 68  ISNPEKIICVGKNYKEHALETGSGIPESPVLFSKFNNTLTGHLNDIII--DFSDSIDYEG 125

Query: 133 ELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLLGKSMDTFCPLGPC 192
           EL +V+G++A  V E DA+ +V GY +A D+SARD Q   +  Q+LLGK+ D F P GP 
Sbjct: 126 ELGIVIGKKARNVDENDAMDYVFGYYIANDVSARDLQYRTS--QWLLGKTPDGFYPNGPF 183

Query: 193 VLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPGDLILTGTP 252
           ++T DEV   + L +    NG   Q S+T  ++  I  L+  IS  +TL+PGD+I TGTP
Sbjct: 184 IVTKDEVNDPMNLDIRTLRNGDTVQHSNTRNMIFDIKYLIGYISKYLTLMPGDVISTGTP 243

Query: 253 GGVGMYRQPPEYLQPGDVLTSEIEKIGAFDVRIEKF 288
            GV +      +++  + +  +IEK+G+   R  K+
Sbjct: 244 EGVILGTNEKNWIKNNETIEVKIEKLGSLKNRFIKY 279


>UniRef50_A0RY21 Cluster: 2-keto-4-pentenoate
           hydratase/2-oxohepta-3-ene-1, 7-dioic acid hydratase;
           n=1; Cenarchaeum symbiosum|Rep: 2-keto-4-pentenoate
           hydratase/2-oxohepta-3-ene-1, 7-dioic acid hydratase -
           Cenarchaeum symbiosum
          Length = 288

 Score =  155 bits (376), Expect = 1e-36
 Identities = 90/246 (36%), Positives = 133/246 (54%), Gaps = 5/246 (2%)

Query: 35  LPTTLLQILRNGDLEKVKKLKSTKPATIPLSSVTLTAPIHGVDKILCIGLNYKDHCQEQN 94
           LPT L   L  G L +V            LS   + API    KI C+  NY DH Q+Q+
Sbjct: 36  LPTRLGGFLFEGWLAEVNDRLDGLEYERGLSEYGIMAPIAEPPKIFCLAFNYADHAQDQD 95

Query: 95  LTPPPVPMVFSKFSSTIIGPDQPVRIRTDVTKKVDWEVELCVVVGREASCVREEDALQHV 154
            +PP  P++  K  + + G    + +     K++D+EVEL +++G+    V    A + +
Sbjct: 96  RSPPDEPVIVMKPRTALCGNGDDI-VMPPFVKELDYEVELALIIGKRCRDVDVIGAKEAI 154

Query: 155 AGYTVAQDISARDWQKEKNMGQFLLGKSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGV 214
            GYT+  D+SARD Q     GQF   K +DTF P GP + ++DEV     L+++  +NG 
Sbjct: 155 FGYTILNDVSARDIQFRD--GQFTRAKGLDTFAPCGPWITSADEVQDPGRLKMTTKVNGR 212

Query: 215 LKQSSSTAQLVHSIP-SLLHRISSVMTLVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTS 273
            +Q SST+++ H  P  ++ ++SS MTL  GD+I TGTP GV +     EYL  GD +  
Sbjct: 213 ARQDSSTSKM-HIKPFEIVSKLSSSMTLEKGDIISTGTPSGVALNNPDSEYLAAGDEIEM 271

Query: 274 EIEKIG 279
           EIE +G
Sbjct: 272 EIEGLG 277


>UniRef50_O28058 Cluster: Uncharacterized protein AF_2225; n=3;
           cellular organisms|Rep: Uncharacterized protein AF_2225
           - Archaeoglobus fulgidus
          Length = 250

 Score =  155 bits (375), Expect = 2e-36
 Identities = 88/218 (40%), Positives = 130/218 (59%), Gaps = 14/218 (6%)

Query: 62  IPLSSVTLTAPIHGVDKILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRIR 121
           +PL++V    P+    KI+ +GLNY DH +E N+  P  P++F K S+ +IG D  + I 
Sbjct: 30  VPLTAVKFLPPVVP-SKIIAVGLNYIDHAEELNMPVPEEPILFMKPSTAVIGHDDCI-IL 87

Query: 122 TDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLLGK 181
             ++++VD+E EL VV+  +   V E +A  ++ GYT   D++ARD Q +   GQ+   K
Sbjct: 88  PQISQRVDYEGELAVVIAEDCRNVPETNAADYILGYTCFNDVTARDLQAKD--GQWTRAK 145

Query: 182 SMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTL 241
           S DTF PLGP +   D+     +L +   +NG + Q S+T+ L+  +  L+  +SSVMTL
Sbjct: 146 SFDTFAPLGPYIAEIDDPS---KLGIQTRVNGKVVQKSNTSNLIFDVFQLVSFVSSVMTL 202

Query: 242 VPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIG 279
             GD+I TGTP GVGM       L+ GDV+  EIEKIG
Sbjct: 203 KAGDVIATGTPAGVGM-------LKDGDVVEVEIEKIG 233


>UniRef50_Q193D4 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=2;
           Desulfitobacterium hafniense|Rep: Fumarylacetoacetate
           (FAA) hydrolase - Desulfitobacterium hafniense (strain
           DCB-2)
          Length = 251

 Score =  154 bits (374), Expect = 2e-36
 Identities = 84/213 (39%), Positives = 130/213 (61%), Gaps = 14/213 (6%)

Query: 67  VTLTAPIHGVDKILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRIRTDVTK 126
           V L AP+    KI+CIGLNY  H +E        P++F K  ++++GP+  + I   +++
Sbjct: 46  VRLLAPVEPT-KIVCIGLNYAKHIEELGHDFHDDPVIFLKPVTSLVGPEDEI-ILPAMSQ 103

Query: 127 KVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLLGKSMDTF 186
           +VD+E EL VV+G+ A  + E+ A  ++ G+T   D++ARD QK+   GQ+   K  DTF
Sbjct: 104 QVDYEAELVVVIGKTAKDLAEDQAEDYIFGFTCGNDVTARDLQKKD--GQWTRSKGFDTF 161

Query: 187 CPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPGDL 246
           CP+GP ++   +      +++   LNG +KQSS T+ L+HS+P L+  IS +MTL PGDL
Sbjct: 162 CPIGPWIVRDLDYR---NVKIRSVLNGEVKQSSQTSHLIHSVPKLVSYISKIMTLNPGDL 218

Query: 247 ILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIG 279
           I+TGTP GVG        ++ GD +  +I+ IG
Sbjct: 219 IMTGTPEGVGP-------MKTGDAIAIDIKGIG 244


>UniRef50_A3KJW3 Cluster: Putative maleylpyruvate isomerase; n=1;
           Streptomyces ambofaciens ATCC 23877|Rep: Putative
           maleylpyruvate isomerase - Streptomyces ambofaciens ATCC
           23877
          Length = 288

 Score =  153 bits (371), Expect = 5e-36
 Identities = 103/278 (37%), Positives = 149/278 (53%), Gaps = 22/278 (7%)

Query: 16  RVGYLEGDDIVDINK----ADSSLPTTLLQ--ILRNGDLEKVKKLKSTKPATIPLSSVTL 69
           R+G ++GDD+VD+      A ++ P   +Q  I      E V+   + +P T PL+   L
Sbjct: 10  RLGVVDGDDLVDVTDQLTGAGTAGPAGAVQRYIETTARGEAVRFDLAGRPRT-PLAEAAL 68

Query: 70  TAPIHGVDKILCIGLNYKDHCQEQNLTPPPVPM-VFSKFSSTIIGPDQPVRIRTDVTKKV 128
            AP+    KI+   +NY DH  E   T     + VF K +S++IGP + + +     K+ 
Sbjct: 69  QAPLPLPGKIIGAPVNYLDHKAEMEYTTSVADLGVFLKANSSVIGPGEDILLPYS-DKRT 127

Query: 129 DWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLLGKSMDTFCP 188
           D E EL VV+GR A+ V  +DAL HV GYT   DI+ R  +           KS DTF P
Sbjct: 128 DQEGELGVVIGRTAAHVSADDALGHVFGYTCVLDITVRSGEDRSTR------KSFDTFTP 181

Query: 189 LGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPGDLIL 248
           LGP V+T+DE+     L + C + G  +Q ++TA L+  +  L+   SSVMTL PGD+I 
Sbjct: 182 LGPWVVTADEIPDPDTLDLRCDVGGTTRQRTNTADLIFGVRELIAYTSSVMTLHPGDVIA 241

Query: 249 TGTPGGVGMYRQPPEYLQPGDVLTSEIEKIGAFDVRIE 286
           TGTP GVG        L  GD +  +IEK+G  +V ++
Sbjct: 242 TGTPAGVGP-------LAHGDRVVLDIEKVGRLEVGVD 272


>UniRef50_Q0CVN6 Cluster: Predicted protein; n=1; Aspergillus
           terreus NIH2624|Rep: Predicted protein - Aspergillus
           terreus (strain NIH 2624)
          Length = 274

 Score =  152 bits (369), Expect = 9e-36
 Identities = 73/194 (37%), Positives = 121/194 (62%), Gaps = 3/194 (1%)

Query: 79  ILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRIRTDVTK-KVDWEVELCVV 137
           + CIGLNYK+H  E  +T P  P VF K ++ I    +P+ + + V   + D+EVEL ++
Sbjct: 65  VRCIGLNYKEHAAEMKMTLPDAPTVFLKANTCISSAAEPIVLPSVVDHDEADYEVELAII 124

Query: 138 VGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLLGKSMDTFCPLGPCVLTSD 197
           +G+    V   +A+ +V GY+VA D++AR  Q + +  Q+   K MD FCPLGPC+++++
Sbjct: 125 IGQRCKNVSVAEAMGYVLGYSVANDVTARKHQGKTS--QWSYAKGMDGFCPLGPCIVSAE 182

Query: 198 EVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPGDLILTGTPGGVGM 257
           ++      ++  SLNG   Q++S   ++ SI  ++  +S   TL+PG +I+TGTP G+G+
Sbjct: 183 KIPDPSVFQLRTSLNGKTMQNASADDMIFSIAEVVSYLSQGHTLLPGTVIITGTPCGIGV 242

Query: 258 YRQPPEYLQPGDVL 271
            + PP +L+PGD L
Sbjct: 243 SQNPPVFLKPGDRL 256


>UniRef50_A5NU93 Cluster: 5-carboxymethyl-2-hydroxymuconate
           Delta-isomerase; n=1; Methylobacterium sp. 4-46|Rep:
           5-carboxymethyl-2-hydroxymuconate Delta-isomerase -
           Methylobacterium sp. 4-46
          Length = 288

 Score =  152 bits (368), Expect = 1e-35
 Identities = 89/262 (33%), Positives = 145/262 (55%), Gaps = 8/262 (3%)

Query: 23  DDIVDINKADSSLPTTLLQILRNGD--LEKVKKLK--STKPATIPLSSVTLTAPIHGVDK 78
           D + D+   D  LP  +  ++  G   +++ KK    +T  A +   S+     I    K
Sbjct: 20  DGLYDLRMVDPGLPDGVGGLVAGGPEFMDRAKKAAGAATGAARLDEGSLRYRPLIERPGK 79

Query: 79  ILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRIRTDVTKKVDWEVELCVVV 138
           I+CIG NY  H +E    P   P VF + +++++   +P+ IR   + K D+E EL  VV
Sbjct: 80  IICIGRNYAAHAREGGAEPLDYPDVFMRGANSLVAHGEPL-IRPRCSDKFDYEGELVFVV 138

Query: 139 GREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLLGKSMDTFCPLGPCVLTSDE 198
           GR+A  V  ++A   +AGY+V  + S RD+Q+     Q+ +GK+ D     GP ++T DE
Sbjct: 139 GRKARHVGLDEACGIIAGYSVFNEGSIRDYQRRAT--QWTMGKNFDGTGGFGPDLVTPDE 196

Query: 199 VGAAVE-LRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPGDLILTGTPGGVGM 257
           +    + LR++ +LNG + Q  +T   +  +  ++  ++  MTL PGD++LTGTP GVG 
Sbjct: 197 LPDGADGLRLTTTLNGHVMQDGNTHDFIFPVARIVAILTEAMTLEPGDVVLTGTPSGVGY 256

Query: 258 YRQPPEYLQPGDVLTSEIEKIG 279
            R PP +++PGDV+   IEK+G
Sbjct: 257 ARNPPVFIKPGDVVEVTIEKVG 278


>UniRef50_A6NUP5 Cluster: Putative uncharacterized protein; n=1;
           Bacteroides capillosus ATCC 29799|Rep: Putative
           uncharacterized protein - Bacteroides capillosus ATCC
           29799
          Length = 250

 Score =  151 bits (367), Expect = 2e-35
 Identities = 89/218 (40%), Positives = 126/218 (57%), Gaps = 14/218 (6%)

Query: 62  IPLSSVTLTAPIHGVDKILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRIR 121
           +PL    L AP     KI+C+G NY DH  E     P  P++F K  +T+  P+  V   
Sbjct: 40  LPLEQCRLLAPCEPT-KIICVGKNYYDHAMEMGEGVPDRPILFIKAPNTVNHPEGEVSA- 97

Query: 122 TDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLLGK 181
            D  +++D+E EL  VV + A  V+ E+   ++ GYT   D++ARD QK    GQ+  GK
Sbjct: 98  PDFVERLDYEGELAFVVKKRAKNVKAEEYGDYILGYTCLNDVTARDIQKSD--GQWSRGK 155

Query: 182 SMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTL 241
           SMD F P+GP  L +DEV  + +L++   LNG   QSS T+  +  IP+L+  I++ MTL
Sbjct: 156 SMDGFAPIGP--LVTDEVDGS-DLKIETRLNGKTVQSSRTSLFMTKIPALMEFITASMTL 212

Query: 242 VPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIG 279
            PGD++ TGTP G+G        +QPGDV+  EIE IG
Sbjct: 213 EPGDVVTTGTPAGIGA-------MQPGDVVEVEIEGIG 243


>UniRef50_A6CED1 Cluster: 5-carboxymethyl-2-hydroxymuconate
           delta-isomerase; n=1; Planctomyces maris DSM 8797|Rep:
           5-carboxymethyl-2-hydroxymuconate delta-isomerase -
           Planctomyces maris DSM 8797
          Length = 310

 Score =  151 bits (367), Expect = 2e-35
 Identities = 88/234 (37%), Positives = 135/234 (57%), Gaps = 15/234 (6%)

Query: 59  PATIPLSSVTLTAPIHGVDKILCIGLNYKDHCQE----QNLTPPPVPMVFSKF-SSTIIG 113
           P +I    V L  P+    K+L +  NY  H +E            P VF K  S+T+  
Sbjct: 72  PLSIQTDEVQLLVPVPEPSKLLLLAGNYSKHIEEGGGKAEERQKTFPYVFMKPPSTTLTH 131

Query: 114 PDQPVRIRTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQ---- 169
           P QPV+I       +DWE+EL +V+G+    V E +AL +VAGYTV  DIS R ++    
Sbjct: 132 PGQPVKIPEVSPDYIDWELELGIVIGKSCKGVSEAEALDYVAGYTVINDISDRKFRPNPG 191

Query: 170 ---KEKN-MGQFLLGKSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLV 225
              +EK+    +  GK  DTFCP+GPCV  +D++     L++  S+NG ++Q +STA+++
Sbjct: 192 RTLREKDTFFDWQHGKWHDTFCPMGPCVTPADDIPDPQTLKMKLSVNGNVEQDASTAEMI 251

Query: 226 HSIPSLLHRISSVMTLVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIG 279
             + +++  ISS + L PGD+I TGTP GVG  +   ++L+ GDV+ +EI++IG
Sbjct: 252 FPVAAIVEFISSFVQLEPGDVISTGTPSGVGASKN--KFLKNGDVMKAEIDQIG 303


>UniRef50_Q7ML43 Cluster: Putative uncharacterized protein VV1584;
           n=2; Vibrio|Rep: Putative uncharacterized protein VV1584
           - Vibrio vulnificus (strain YJ016)
          Length = 259

 Score =  151 bits (366), Expect = 2e-35
 Identities = 80/222 (36%), Positives = 124/222 (55%), Gaps = 9/222 (4%)

Query: 61  TIPLSSVTLTAPIHGVDKILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRI 120
           ++P    T  +PI     I  +GLNY DH  E    PP  P+VF K ++T+    QP   
Sbjct: 30  SLPAGQFTWLSPIENPGTIFALGLNYADHASELAFEPPKEPLVFLKGANTLTAHQQPSYR 89

Query: 121 RTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLLG 180
             D+ + + +E EL  VVG+EA  V+ EDA+ ++ G+T+  D + RD+  E      L  
Sbjct: 90  PNDI-EFMHYECELVAVVGKEARNVKREDAMDYIQGFTICNDYAIRDYL-ENYYRPNLRV 147

Query: 181 KSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMT 240
           KS D+ CP+GP ++  D++     L ++  +NG L Q  +T+ ++  +P L+  +SS MT
Sbjct: 148 KSRDSLCPIGPWIVDCDDIEDVNNLALTTHVNGELTQQGNTSDMIFDVPFLIEYLSSFMT 207

Query: 241 LVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIGAFD 282
           L PGDLI TGTP G+       + +QPGDV+   IE +G+ +
Sbjct: 208 LKPGDLIATGTPKGL-------KDIQPGDVVRCTIEGVGSLE 242


>UniRef50_A5P4N8 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate
           decarboxylase; n=1; Methylobacterium sp. 4-46|Rep:
           5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase -
           Methylobacterium sp. 4-46
          Length = 480

 Score =  151 bits (366), Expect = 2e-35
 Identities = 94/274 (34%), Positives = 147/274 (53%), Gaps = 15/274 (5%)

Query: 25  IVDINKADSSL----PTTLLQILRNGD---LEKVKKLKSTKPATIPL--SSVTLTAPIHG 75
           I+D+  A +SL    P  +  +L+NG    L  V    +  P T+ L   +V     +  
Sbjct: 208 ILDVTAAAASLGLPAPADMDDLLQNGKGGLLRAVADGAARGPDTLYLREEAVRFAPLVTR 267

Query: 76  VDKILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRIRTDVTKKVDWEVELC 135
            +KI+ +G NY+ H  E     P  P +F+K+++ +      +++ T V ++ D+EVEL 
Sbjct: 268 PEKIIMMGFNYRHHAAETGTPIPKDPPLFNKYNNALNHHGGTIKLPTAVAREFDYEVELV 327

Query: 136 VVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLLGKSMDTFCPLGPCVLT 195
           +V GRE S V E +AL  VAGY    D SARD Q   +  QF++GK+ D F PLGP ++T
Sbjct: 328 IVFGRECSNVSEAEALDCVAGYATGNDFSARDLQTLTS--QFMIGKTADGFAPLGPYLVT 385

Query: 196 SDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPGDLILTGTPGGV 255
           SD V     LR+   +NGV +Q  +T  ++ +   L+   S +MT+ PGD+  TGTP GV
Sbjct: 386 SDLVKDPNNLRLETRVNGVQRQDWNTNDMIFNCRQLISFASKMMTIKPGDIFYTGTPHGV 445

Query: 256 GMYRQPP----EYLQPGDVLTSEIEKIGAFDVRI 285
               + P    ++L+PGD +   +E +G    R+
Sbjct: 446 IFGEKKPRAERQWLKPGDEVACSLEGLGELRFRL 479


>UniRef50_UPI000023DA6E Cluster: hypothetical protein FG11179.1;
           n=1; Gibberella zeae PH-1|Rep: hypothetical protein
           FG11179.1 - Gibberella zeae PH-1
          Length = 281

 Score =  151 bits (365), Expect = 3e-35
 Identities = 81/208 (38%), Positives = 122/208 (58%), Gaps = 6/208 (2%)

Query: 79  ILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGP-DQPVRIRTDVTK-KVDWEVELCV 136
           ++CIGLNY DH +E  +  P VP+VF K  + + GP D  V   T   K ++D+E EL +
Sbjct: 66  VVCIGLNYTDHAEEAQMPIPKVPVVFFKPVTALAGPHDDLVLPHTSWEKGRLDYESELVI 125

Query: 137 VVGREASCVREEDALQHVAGYT--VAQDISARDWQKEKNMG--QFLLGKSMDTFCPLGPC 192
           V+G++AS V ++DAL +V  YT     DIS R WQ +  +G  Q+   K  D   P+GP 
Sbjct: 126 VIGKKASRVSKDDALDYVFSYTFHAGNDISNRAWQLDPQLGGGQWCYSKCFDCSAPIGPA 185

Query: 193 VLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPGDLILTGTP 252
           +++ D +G+AV L +  +LN    Q  +T  ++  +  ++  +S  MTL+PG  I TGTP
Sbjct: 186 IVSKDILGSAVGLGIRGTLNDTQSQDGNTNNMIFGVAEIVSFLSQGMTLLPGTFIFTGTP 245

Query: 253 GGVGMYRQPPEYLQPGDVLTSEIEKIGA 280
            GVG  ++P   ++ GDV   EI+ IGA
Sbjct: 246 AGVGFGKKPQISVKEGDVTQVEIDGIGA 273


>UniRef50_Q313F7 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate
           decarboxylase; n=3; Desulfovibrio|Rep:
           5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase -
           Desulfovibrio desulfuricans (strain G20)
          Length = 264

 Score =  150 bits (364), Expect = 4e-35
 Identities = 87/208 (41%), Positives = 120/208 (57%), Gaps = 12/208 (5%)

Query: 72  PIHGVDKILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRIRTDVTKKVDWE 131
           P+    KI+C+G+N++DH +E     P  P+ F K SS +IG  QPV +  + + +V+ E
Sbjct: 44  PVVTPSKIVCVGMNFRDHAEEIGFPVPEEPVFFLKPSSAVIGSGQPVVLPAE-SGRVEHE 102

Query: 132 VELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLLGKSMDTFCPLGP 191
            EL VV+GR A  +  ED   HV GYT A D++ARD Q     G F   K  DTF P+GP
Sbjct: 103 AELGVVIGRAARNITPEDVPAHVFGYTCANDVTARDLQSRD--GLFGRCKGFDTFAPVGP 160

Query: 192 CVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPGDLILTGT 251
            + T  EV     L +   +NG L+Q  STA ++ S   ++  +S VMTL+PGDLILTGT
Sbjct: 161 WIET--EVPDLSSLGIRAMVNGELRQQGSTADMLFSPHEIVAAVSRVMTLLPGDLILTGT 218

Query: 252 PGGVGMYRQPPEYLQPGDVLTSEIEKIG 279
           P GVG        L+ GD +  EI+ +G
Sbjct: 219 PAGVGP-------LEDGDEVRVEIDGVG 239


>UniRef50_A6M380 Cluster: 5-carboxymethyl-2-hydroxymuconate
           Delta-isomerase; n=1; Clostridium beijerinckii NCIMB
           8052|Rep: 5-carboxymethyl-2-hydroxymuconate
           Delta-isomerase - Clostridium beijerinckii NCIMB 8052
          Length = 294

 Score =  149 bits (361), Expect = 8e-35
 Identities = 83/251 (33%), Positives = 143/251 (56%), Gaps = 11/251 (4%)

Query: 38  TLLQILRNGDLEKVKK-LKSTKPATIPLSSVTLTAPIHGVDK-ILCIGLNYKDHCQE--- 92
           +L++ + + +++ ++K L +     I + +++   PI   ++ I+C+G+NY +H  E   
Sbjct: 39  SLIENITDHEMDLLQKSLTNNDKEYISIENISKMPPIPNPNQDIICLGINYMEHAVESAR 98

Query: 93  -QNLT---PPPVPMVFSKFSSTIIGPDQPVRIRTDVTKKVDWEVELCVVVGREASCVREE 148
            +N       P  + FSK  +T       +     +   +D+E EL V++G++A  V +E
Sbjct: 99  YKNEAFGGDRPYAVYFSKRVNTATADGDYIPSYPQIVDSLDYEAELAVIIGKDAKDVPKE 158

Query: 149 DALQHVAGYTVAQDISARDWQKEKNMGQFLLGKSMDTFCPLGPCVLTSDEVGAAVELRVS 208
            A  +V GYT+  D+SAR+ Q      Q+  GKS+D F P+GPC++T +E      LR+ 
Sbjct: 159 KAFDYVFGYTIINDVSARNLQTRHK--QWYFGKSLDGFTPMGPCIVTKNEFVNPPVLRIC 216

Query: 209 CSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPGDLILTGTPGGVGMYRQPPEYLQPG 268
             +NG L+Q+S+T  ++ SI  ++H +S  +TL  G +I  GTP GVGM   PP++L+ G
Sbjct: 217 SRVNGELRQNSTTDLMITSIQDVIHELSQGITLKVGTIIAMGTPAGVGMGFIPPKFLKTG 276

Query: 269 DVLTSEIEKIG 279
           D++  EIE IG
Sbjct: 277 DIVECEIEGIG 287


>UniRef50_A2BJD1 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=1;
           Hyperthermus butylicus DSM 5456|Rep: Fumarylacetoacetate
           (FAA) hydrolase - Hyperthermus butylicus (strain DSM
           5456 / JCM 9403)
          Length = 338

 Score =  149 bits (361), Expect = 8e-35
 Identities = 79/239 (33%), Positives = 134/239 (56%), Gaps = 2/239 (0%)

Query: 47  DLEKVKKLKSTKPATIPLSSVTLTAPIHGVDKILCIGLNYKDHCQEQNLTPPPVPMVFSK 106
           +LE + ++ S+    +PLS+V L AP+   +KI+CIG+NY+ H +E  +  P  P +F K
Sbjct: 90  ELEGLARVVSSSDRGLPLSAVRLLAPVDKPEKIICIGVNYRAHARESGVELPGTPNLFVK 149

Query: 107 FSSTIIGPDQPVRIRTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISAR 166
             ++I+GP  PV + + V  K+D EVEL  V+G  A  +   +A   V G+ V  D+++R
Sbjct: 150 TGNSIVGPGDPVVVHS-VGLKLDGEVELAAVIGIPARSIPPSEAPDVVWGFMVLNDVTSR 208

Query: 167 DWQKEKNMGQFLLGKSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVH 226
             Q+E  + Q+   KS DT+ P GP ++    V    +  +   ++G++ +  +T  +VH
Sbjct: 209 LEQRELGISQWWRAKSHDTYAPTGPIIVPRHMVSIG-DTELELVVDGIVARRGNTGDMVH 267

Query: 227 SIPSLLHRISSVMTLVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIGAFDVRI 285
           S+  ++   S+   LVPGD+I TGTP G     +P +  +PG V+ +    IG  + R+
Sbjct: 268 SVWDIVSVASTSALLVPGDIICTGTPAGTMPDGKPAKTPEPGSVMRACARGIGCIENRV 326


>UniRef50_Q39LG9 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate
           decarboxylase; n=3; Burkholderiaceae|Rep:
           5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase -
           Burkholderia sp. (strain 383) (Burkholderia cepacia
           (strain ATCC 17760/ NCIB 9086 / R18194))
          Length = 306

 Score =  149 bits (360), Expect = 1e-34
 Identities = 83/227 (36%), Positives = 125/227 (55%), Gaps = 11/227 (4%)

Query: 63  PLSSVTLTAPIHGVDKILCIGLNYKDHCQEQNLTPPP----VPMVFSKFSSTIIGPDQPV 118
           PL+   L  P +   +I     NY +H +E      P     P +F K  ++++ P    
Sbjct: 78  PLAGYRLRVP-YAPRRIFAAASNYYEHAREMGTELAPREESTPYMFMKAETSVV-PTLAE 135

Query: 119 RIRTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMG--- 175
            +     ++VDWEVEL VV+G+    +   DA  +VAGYT+  D+SARD  +  +     
Sbjct: 136 VVMPPHAERVDWEVELAVVIGKPGRHIAVADAFDYVAGYTILNDVSARDLNRRTDYPFKH 195

Query: 176 QFLLGKSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRI 235
            +  GKS DTF PLGP ++    +     LR+  ++NG + Q  +T +++ SI   +H +
Sbjct: 196 DWFRGKSFDTFGPLGPWLVPRACIAEPQNLRMRLAVNGEMMQDGNTGEMIFSIAEQIHYL 255

Query: 236 SSVMTLVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIGAFD 282
           SS++TL PGDLI TGTP GVGM R    YLQPGDV+ + I+ IG+ +
Sbjct: 256 SSILTLQPGDLIATGTPTGVGMGR--GIYLQPGDVMVASIDGIGSIE 300


>UniRef50_Q0LZE6 Cluster: 5-carboxymethyl-2-hydroxymuconate
           delta-isomerase; n=1; Caulobacter sp. K31|Rep:
           5-carboxymethyl-2-hydroxymuconate delta-isomerase -
           Caulobacter sp. K31
          Length = 293

 Score =  147 bits (356), Expect = 3e-34
 Identities = 92/284 (32%), Positives = 147/284 (51%), Gaps = 11/284 (3%)

Query: 1   MKLVQFSYKDSPKNIRVGYLEGDDIVDINKADSSLPTTLLQILRNGD--LEKVKKLKSTK 58
           M+L+ F    +P    VG   G++++D+  A   LP  +  +L  G   L   ++  +  
Sbjct: 1   MRLLSFELNGAPA---VGVRLGEEVIDLGAAAPDLPRDIQALLAAGPEALAAAERAAAAA 57

Query: 59  P--ATIPLSSVTLTAPIHGVDKILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQ 116
           P  A  PL+ V    PI   DKI+ +G  Y  H  E        P +F +   +++  +Q
Sbjct: 58  PGHARHPLAGVRHLVPIPRPDKIIGLGKTYMKHVAEMKAESSSFPGMFLRVPDSLVAHNQ 117

Query: 117 PVRIRTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQ 176
           P+  R + +  +D+E EL VV+G+    +  E+AL+HVAGY    D S R +    +   
Sbjct: 118 PIW-RPEASDTLDYEGELMVVIGQGGRMISRENALKHVAGYACHNDGSVRAYNYIPSA-- 174

Query: 177 FLLGKSMDTFCPLGPCVLTSDEVGAAVE-LRVSCSLNGVLKQSSSTAQLVHSIPSLLHRI 235
              GK+       GP ++T+DE+    + LR++  +NG L+QS+  A+L   +  L+H +
Sbjct: 175 VTAGKNFLNTGGFGPEIVTADELPPGCKGLRLTTHVNGDLRQSADVAELHWDVAHLVHLM 234

Query: 236 SSVMTLVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIG 279
           S++ TL PGDLI TGTP G       P++L PGDV+  EIE +G
Sbjct: 235 STIFTLYPGDLIATGTPSGCAAASANPQWLVPGDVVRVEIEGVG 278


>UniRef50_Q5KJF0 Cluster: Mitochondrion protein, putative; n=1;
           Filobasidiella neoformans|Rep: Mitochondrion protein,
           putative - Cryptococcus neoformans (Filobasidiella
           neoformans)
          Length = 336

 Score =  147 bits (355), Expect = 4e-34
 Identities = 88/283 (31%), Positives = 160/283 (56%), Gaps = 13/283 (4%)

Query: 1   MKLVQFSYKDSPKNIRVGYLEGDD--IVDINKADSSLPTTLLQILRNGDLEKVKKLKSTK 58
           MK V +  +  P+ I VG ++  +  +  ++  D++L  T+ Q++   D      L    
Sbjct: 18  MKFVSYRSRLHPQGI-VGLVDSTEQFVAPLSFPDNTLVRTMQQLIEEWDATHRHLLHGAP 76

Query: 59  PATIPLSSVTLTAPIHGVDKILCIGLNYKDHCQEQNLTPPPVP--MVFSKFSSTIIGPDQ 116
             ++ +  V + AP+ G D ++C+G NY++H +        V   ++F+K +++IIG +Q
Sbjct: 77  MESLDI--VEILAPLRGRD-VICVGKNYREHAEWVRSLFKLVKYVVIFTKRATSIIGTNQ 133

Query: 117 PVRIRTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQ 176
            +     VT+ +D+E EL +++G+    +  EDA  +V G T+  D++AR+ Q++    Q
Sbjct: 134 EIYPHPRVTQTLDYEGELGIIIGKAGIQISREDAWDYVWGATIINDVTARERQRDHK--Q 191

Query: 177 FLLGKSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRIS 236
           F +GKS+DTFCP+GP  + S  +     + +   +NG ++QS++T+QL+  IP+L+   S
Sbjct: 192 FYIGKSLDTFCPMGPYAVHSSVLDWR-NMMLETRVNGQIRQSANTSQLIFDIPALIATCS 250

Query: 237 SVMTLVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIG 279
             +TL PGD+I TGTP GV +     E+L+  DV+   +  +G
Sbjct: 251 MGITLQPGDVISTGTPAGVCL--SSGEFLKHRDVIDISMSGLG 291


>UniRef50_O58377 Cluster: Uncharacterized protein PH0643; n=4;
           Thermococcaceae|Rep: Uncharacterized protein PH0643 -
           Pyrococcus horikoshii
          Length = 230

 Score =  146 bits (354), Expect = 6e-34
 Identities = 85/213 (39%), Positives = 121/213 (56%), Gaps = 13/213 (6%)

Query: 78  KILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRIRTDVTKKVDWEVELCVV 137
           KI+ +  NY +H +E    PP  P++F K  S +IGP   + I    +K+VD EVEL V+
Sbjct: 22  KIVALAKNYAEHAREMGSEPPEEPIIFLKPPSALIGPGSSI-ILPRRSKRVDHEVELAVI 80

Query: 138 VGREASCVREEDALQHVAGYTVAQDISARDWQKE--KNMGQFLLGKSMDTFCPLGPCVLT 195
           +G+ A  V    A  ++ GYT+  DI+ARD Q E  K    + + K  DTF P+GP V+ 
Sbjct: 81  MGKRAKNVPASKAFDYILGYTIILDITARDLQAEARKKGYPWTISKGFDTFAPIGPRVVD 140

Query: 196 SDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPGDLILTGTPGGV 255
           S E+  + +L +   +NG ++Q   T+Q++  IP L+  IS +MTL PGD+I TGTP GV
Sbjct: 141 SRELDPS-DLEIGLKVNGKIRQLGRTSQMIFKIPELIEYISHIMTLEPGDIIATGTPPGV 199

Query: 256 GMYRQPPEYLQPGDVLTSEIEKIG--AFDVRIE 286
           G  R        GD + + IE IG   FDV  E
Sbjct: 200 GPLRH-------GDRIEAWIEGIGKMEFDVLAE 225


>UniRef50_Q1IVB8 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate
           decarboxylase; n=1; Acidobacteria bacterium
           Ellin345|Rep: 5-oxopent-3-ene-1,2,5-tricarboxylate
           decarboxylase - Acidobacteria bacterium (strain
           Ellin345)
          Length = 263

 Score =  146 bits (353), Expect = 8e-34
 Identities = 78/200 (39%), Positives = 116/200 (58%), Gaps = 6/200 (3%)

Query: 58  KPATIPLSSVTLTAPIHGVDKILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQP 117
           +P  + L    L A +    KI+C+G NYK H +E     P  P++FSK +S II P   
Sbjct: 44  EPLHVLLEEAELLASVVPT-KIVCVGRNYKAHAEELGHEIPKYPLIFSKPTSAIIAPGAD 102

Query: 118 VRIRTDVTKKVDWEVELCVVVGREASCVREE-DALQHVAGYTVAQDISARDWQKEKNMGQ 176
           ++    ++++VD+E EL V++GRE   + E+ D   ++ GYTV  D++ARD Q +   GQ
Sbjct: 103 IKRPAKLSQRVDYEGELGVIIGRECRHIPEDHDVRSYIHGYTVVNDVTARDLQNKD--GQ 160

Query: 177 FLLGKSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRIS 236
           +   K  DTFCP+GP V  +D +     + V   +NG ++Q  +T+  +  +  +L  IS
Sbjct: 161 WTRAKGFDTFCPVGPIV--NDALDPWTGVEVETRVNGAVRQHGNTSSFIFPLDVILRFIS 218

Query: 237 SVMTLVPGDLILTGTPGGVG 256
            VMTL PGDLI TGTP GVG
Sbjct: 219 EVMTLFPGDLIATGTPEGVG 238


>UniRef50_Q0S9S7 Cluster: Possible fumarylacetoacetate hydrolase;
           n=2; Actinomycetales|Rep: Possible fumarylacetoacetate
           hydrolase - Rhodococcus sp. (strain RHA1)
          Length = 281

 Score =  145 bits (352), Expect = 1e-33
 Identities = 79/230 (34%), Positives = 123/230 (53%), Gaps = 5/230 (2%)

Query: 51  VKKLKSTKPATIPLSSVTLTAPIHGVDKILCIGLNYKDHCQEQNLTPPPVPMVFSKFSST 110
           V + +  +   I ++ V++  P+    +++C+GLNYK H  E   TPPP P +F +++ +
Sbjct: 41  VARAEHLESPEIDVTLVSVVPPVPDSARVICVGLNYKAHAAEGGFTPPPYPTLFGRWTPS 100

Query: 111 IIGPDQPVRIRTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQK 170
           +     P  +  +    +DWE E+   +G     V        V GY    D++AR  + 
Sbjct: 101 LSVDGAPTPVPANEAG-LDWEGEVAAFIGTRLESVDAATGQAGVLGYACFNDLTAR--KA 157

Query: 171 EKNMGQFLLGKSMDTFCPLGPCVLTSDEVGAAVE-LRVSCSLNGVLKQSSSTAQLVHSIP 229
           +K   Q+ LGK+ D   PLGP V  + EVG   + LRV   +NG + Q  +T  L+ S+ 
Sbjct: 158 QKLTAQWTLGKNGDRSGPLGPLV-PAGEVGDLSDGLRVQTRVNGTVVQDGNTRDLIFSVG 216

Query: 230 SLLHRISSVMTLVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIG 279
            ++  +S   TL PGD+I TGTP GVG  R PP  L PGD++  EI+K+G
Sbjct: 217 EIIALVSETFTLHPGDIIATGTPEGVGYVRNPPWLLGPGDIVEVEIDKLG 266


>UniRef50_Q0SFL0 Cluster: Maleylpyruvate isomerase; n=4;
           Actinomycetales|Rep: Maleylpyruvate isomerase -
           Rhodococcus sp. (strain RHA1)
          Length = 275

 Score =  144 bits (350), Expect = 2e-33
 Identities = 79/202 (39%), Positives = 115/202 (56%), Gaps = 4/202 (1%)

Query: 78  KILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRIRTDVTKKVDWEVELCVV 137
           KI+C+GLNY +H QE     P  P +F+KF   + GP   V + +    ++DWE EL  V
Sbjct: 69  KIICVGLNYANHIQEMGRDLPEYPTLFAKFKEALTGPYDDVIVPSYAAAQLDWEGELAFV 128

Query: 138 VGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLLGKSMDTFCPLGPCVLTSD 197
           VG++A  V E DA Q++AGY+V  D + RD+Q      Q+  GK+ +     GP + T+D
Sbjct: 129 VGKQAYQVPEADAEQYIAGYSVMNDYTMRDYQYRTL--QWDQGKTFEKTSGFGPFLTTTD 186

Query: 198 EVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPGDLILTGTPGGVGM 257
                  L     L G + QS++T  LV +   L+  IS ++TL PGD+++TGTPGGVG 
Sbjct: 187 SYTFGGTL--VTKLEGQVVQSTTTDDLVFTPARLVEYISHIVTLQPGDVVITGTPGGVGH 244

Query: 258 YRQPPEYLQPGDVLTSEIEKIG 279
            R+P  Y+Q G  +   IE +G
Sbjct: 245 ARKPGLYIQDGQTVEVTIEGLG 266


>UniRef50_Q0LC36 Cluster: 5-carboxymethyl-2-hydroxymuconate
           delta-isomerase; n=1; Herpetosiphon aurantiacus ATCC
           23779|Rep: 5-carboxymethyl-2-hydroxymuconate
           delta-isomerase - Herpetosiphon aurantiacus ATCC 23779
          Length = 293

 Score =  144 bits (349), Expect = 2e-33
 Identities = 78/195 (40%), Positives = 114/195 (58%), Gaps = 9/195 (4%)

Query: 60  ATIPLSSVTLTAPI-HGVDKILCIGLNYKDHCQEQ------NLTPPPVPMVFSKFSSTII 112
           A I L+   L AP+   +  + C+GLNY  H +E        +  P  P+ F+K  + I 
Sbjct: 56  AGIQLNMDQLLAPLPRPLKNVFCVGLNYAAHARESLQAKGLEVKMPEHPVFFTKPPTAIN 115

Query: 113 GPDQPVRIRTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEK 172
            P   + I   V++++DWEVEL VV+G+    +  E A++HV GYTV  D+SARD Q   
Sbjct: 116 SPTGEIVIDPAVSERIDWEVELGVVIGKAGKNISHEQAMEHVWGYTVINDVSARDLQMRH 175

Query: 173 NMGQFLLGKSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLL 232
              QF  GK++D  CP+GP ++TSDE+     L V   +NG +KQ S+T  L+ +IP+L+
Sbjct: 176 Q--QFFKGKALDGSCPMGPWIITSDELTDPHNLVVRLRVNGEIKQESNTNDLIFNIPTLI 233

Query: 233 HRISSVMTLVPGDLI 247
           H +S  MTL PGD+I
Sbjct: 234 HVLSQGMTLEPGDII 248


>UniRef50_A5FQA8 Cluster: 5-carboxymethyl-2-hydroxymuconate
           Delta-isomerase; n=3; Dehalococcoides|Rep:
           5-carboxymethyl-2-hydroxymuconate Delta-isomerase -
           Dehalococcoides sp. BAV1
          Length = 253

 Score =  143 bits (347), Expect = 4e-33
 Identities = 77/179 (43%), Positives = 113/179 (63%), Gaps = 6/179 (3%)

Query: 78  KILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRIRTDVTKKVDWEVELCVV 137
           KI+ IGLNYK H  E     P +P++F K +S IIGP+  + I+   +++VD+E EL V+
Sbjct: 56  KIIAIGLNYKAHAGEMAEDLPKLPLIFFKNASGIIGPEDNI-IKPGQSERVDYEGELAVI 114

Query: 138 VGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLLGKSMDTFCPLGPCVLTSD 197
           + ++   ++ EDA  ++ GY+   D++ARD QK    GQ+   K  DTF   GP + T  
Sbjct: 115 IRKKTRNIKPEDAFDYILGYSCFNDVTARDLQKID--GQWSRAKGFDTFAVCGPWIET-- 170

Query: 198 EVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPGDLILTGTPGGVG 256
           E+   V+L +   LNG LKQ +STA ++ SIP ++  IS VMTL+PGD+I TGTP G+G
Sbjct: 171 ELDPQVQL-LETYLNGKLKQRTSTADMIFSIPRIVSFISEVMTLLPGDIIATGTPSGIG 228


>UniRef50_Q5V4M0 Cluster: 2-hydroxyhepta-24-diene-1,7-dioate
           isomerase; n=4; Halobacteriaceae|Rep:
           2-hydroxyhepta-24-diene-1,7-dioate isomerase -
           Haloarcula marismortui (Halobacterium marismortui)
          Length = 257

 Score =  143 bits (346), Expect = 5e-33
 Identities = 84/204 (41%), Positives = 119/204 (58%), Gaps = 16/204 (7%)

Query: 78  KILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRIRTDVTKKVDWEVELCVV 137
           K++CIG NY DH +E +   P  PM+F K  + +    + + + +   +++D+E EL VV
Sbjct: 59  KVVCIGRNYADHAEEMDSELPDRPMLFLKAPNAVASHGKHLTMPSG-KERIDYEAELGVV 117

Query: 138 VGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLLGKSMDTFCPLGPCVLTSD 197
           +G +   V E  A+  VAGYT   DIS RD Q+ +    ++ GK+ D  CP+GP V T +
Sbjct: 118 IGEQCRNVSESGAMDVVAGYTCVNDISNRDDQRREQ--NWVRGKAFDNACPIGPLVATPE 175

Query: 198 EV--GAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPGDLILTGTPGGV 255
            V   A++ELR    LNG  KQSSS   L+ S+P L+  I+S MTL PGD+I TGTP GV
Sbjct: 176 HVPEDASIELR----LNGETKQSSSREHLIFSVPELIAEITSYMTLEPGDVIATGTPEGV 231

Query: 256 GMYRQPPEYLQPGDVLTSEIEKIG 279
           G        ++ GD +  EIE IG
Sbjct: 232 GP-------MEDGDEVEVEIEGIG 248


>UniRef50_Q13HB6 Cluster: Putative fumarylacetoacetate (FAA)
           hydrolase; n=1; Burkholderia xenovorans LB400|Rep:
           Putative fumarylacetoacetate (FAA) hydrolase -
           Burkholderia xenovorans (strain LB400)
          Length = 257

 Score =  142 bits (345), Expect = 7e-33
 Identities = 82/217 (37%), Positives = 118/217 (54%), Gaps = 13/217 (5%)

Query: 64  LSSVTLTAPIHGVDKILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRIRTD 123
           L+   L  P+    ++  +G+NY  H  E     P +P  F   ++  IGP + + +R  
Sbjct: 42  LADAQLLCPLPA-PRLFAVGMNYVGHIAEAGAKTPVIPQFFMMPTTAAIGPGEAI-VRPR 99

Query: 124 VTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQ-KEKNMGQFLLGKS 182
             + V  E EL +V+GR    +  E AL HV GYT A D+S R  Q +E   G  L+GK+
Sbjct: 100 EAQVVHHEAELAIVIGRRGRRIDVERALDHVFGYTCANDVSERVIQNREMGYGCLLVGKA 159

Query: 183 MDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLV 242
            DTFCPLGP + T  + G    LRV  S+NG  +Q  +T+ L+ ++P ++  +S  +TL+
Sbjct: 160 FDTFCPLGPVIATGLDAG---NLRVRASVNGSPRQDGNTSDLLFTVPHIVSYLSQAVTLL 216

Query: 243 PGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIG 279
           PGD+ILTGTP GVG        L  GDV    I+ IG
Sbjct: 217 PGDVILTGTPSGVGP-------LLSGDVCEITIDGIG 246


>UniRef50_A0LGT2 Cluster: 5-carboxymethyl-2-hydroxymuconate
           delta-isomerase; n=1; Syntrophobacter fumaroxidans
           MPOB|Rep: 5-carboxymethyl-2-hydroxymuconate
           delta-isomerase - Syntrophobacter fumaroxidans (strain
           DSM 10017 / MPOB)
          Length = 235

 Score =  142 bits (345), Expect = 7e-33
 Identities = 83/216 (38%), Positives = 118/216 (54%), Gaps = 22/216 (10%)

Query: 78  KILCIGLNYKDHCQEQNLTP--------PPVPMVFSKFSSTIIGPDQPVRIRTDVTK--- 126
           KI+ +GLNY+ H  E             P  P++F K  + +IGP + + I   + +   
Sbjct: 19  KIIALGLNYRAHIAESTTVKVRGFTDEVPEEPILFPKTPNVLIGPGESIVIPAFLKEYGF 78

Query: 127 ---KVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLLGKSM 183
              + D+E EL V++  E   V   DAL+HV GYT   D+S R+ Q     G F  GKS+
Sbjct: 79  PEPRTDYEAELAVIIKDECKNVGPGDALKHVFGYTCMNDVSQRNLQTGDRAGWFR-GKSL 137

Query: 184 DTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVP 243
           DTF P+GP ++  D++G    LR+ C LNGV  Q S+T  ++  IP ++  +S    L+P
Sbjct: 138 DTFGPIGPVIVRPDDLGDPHNLRICCRLNGVTVQDSNTGSMIFKIPEIIAFVSRNFKLMP 197

Query: 244 GDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIG 279
           GD+I+TGTP GVG  R        GDV+  EIEKIG
Sbjct: 198 GDVIVTGTPSGVGPIRH-------GDVVEVEIEKIG 226


>UniRef50_A1SM04 Cluster: 5-carboxymethyl-2-hydroxymuconate
           delta-isomerase; n=1; Nocardioides sp. JS614|Rep:
           5-carboxymethyl-2-hydroxymuconate delta-isomerase -
           Nocardioides sp. (strain BAA-499 / JS614)
          Length = 269

 Score =  142 bits (344), Expect = 9e-33
 Identities = 82/194 (42%), Positives = 110/194 (56%), Gaps = 4/194 (2%)

Query: 64  LSSVTLTAPIHGVDKILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRIRTD 123
           L  V L AP+    K++ IG NY  H  E     P  P++F K ++++IGP  P+     
Sbjct: 54  LEDVRLLAPVLPRSKVVGIGRNYAAHAAELGNDLPTEPLMFLKPNTSVIGPGDPI-FYPP 112

Query: 124 VTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLLGKSM 183
            T+ + +E EL VV+GR    V  E A   + GYT+  D++ARD Q+     QF   K  
Sbjct: 113 QTQNLHYEGELAVVIGRICRDVPPEQATDVIHGYTIGNDVTARDLQRSDV--QFTRAKGF 170

Query: 184 DTFCPLGPCVLTSDEVGAAVELR-VSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLV 242
           D+FCPLGP + T  +     E R V   LNG L Q  ST  L+  IP+L+  +SSVMTL+
Sbjct: 171 DSFCPLGPWIETDLDPHDFAEGRSVQTHLNGDLVQDGSTKDLIFDIPTLIAYVSSVMTLL 230

Query: 243 PGDLILTGTPGGVG 256
           PGD+ILTGTP GVG
Sbjct: 231 PGDVILTGTPEGVG 244


>UniRef50_Q8NLC0 Cluster: 2-keto-4-pentenoate
           hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase;
           n=5; Actinomycetales|Rep: 2-keto-4-pentenoate
           hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase -
           Corynebacterium glutamicum (Brevibacterium flavum)
          Length = 279

 Score =  140 bits (340), Expect = 3e-32
 Identities = 78/213 (36%), Positives = 113/213 (53%), Gaps = 4/213 (1%)

Query: 69  LTAPIHGVDKILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRIRTDVTKKV 128
           L A +    KI+C+GLNY +H +E     P  P +F KF   +IGP   V +     K +
Sbjct: 60  LDAVVPAPKKIVCVGLNYANHIKEMGRDLPDTPTLFVKFPDALIGPFDDVVVPEWANKAL 119

Query: 129 DWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQ--KEKNMGQFLLGKSMDTF 186
           DWE E+ V++G+ A  V++ DA +++AGY V  D + RD+Q        Q+  GKS++  
Sbjct: 120 DWEGEMAVIIGKRARRVKQADAAEYIAGYAVMNDYTTRDFQYAAPAKTPQWHQGKSLEKS 179

Query: 187 CPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPGDL 246
              GP + T D      EL  +  L G   QS+ T  LV S   L+  I+ +  L  GD+
Sbjct: 180 AGFGPWMTTPDSFEFGGEL--ATYLEGEKVQSTPTNDLVFSPEKLIEYITHIYPLDAGDV 237

Query: 247 ILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIG 279
           I+TGTPGGVG  R P  Y+  G+ +  EI  +G
Sbjct: 238 IVTGTPGGVGHARNPQRYIGDGETVKVEIAGLG 270


>UniRef50_Q1M9K7 Cluster: Putative FAA hydrolase family protein;
           n=1; Rhizobium leguminosarum bv. viciae 3841|Rep:
           Putative FAA hydrolase family protein - Rhizobium
           leguminosarum bv. viciae (strain 3841)
          Length = 282

 Score =  140 bits (340), Expect = 3e-32
 Identities = 78/199 (39%), Positives = 116/199 (58%), Gaps = 17/199 (8%)

Query: 69  LTAPIHGVDKILCIGLNYKDHCQEQNLTP-----------PPVPMVFSKFSSTIIGPDQP 117
           +T P H V    C+G NY  H  E   +            P  P++F+K SS++  P   
Sbjct: 80  ITNPPHNV---FCVGKNYHAHAHEFTKSGFDAGATAAEAIPEHPIIFTKPSSSLARPFGD 136

Query: 118 VRIRTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQF 177
           + +   + + VD+E EL VV+G+    +  E AL HV GYTV  D++ARD QK+    Q+
Sbjct: 137 IPLWPGLDEAVDYEAELAVVIGKAGRFITAERALDHVFGYTVFNDVTARDLQKKHK--QW 194

Query: 178 LLGKSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISS 237
            LGK +D F P+GP ++T DE+  A  + ++C++NG  +Q +ST  L+  IP+L+  IS 
Sbjct: 195 FLGKGIDGFGPIGPWIVTKDELDIA-NVEITCTVNGEERQKTSTKDLIFDIPTLIEVISR 253

Query: 238 VMTLVPGDLILTGTPGGVG 256
            +TL+PGD+I TGTP GVG
Sbjct: 254 SVTLLPGDIIATGTPAGVG 272


>UniRef50_Q9HJ20 Cluster: 2-hydroxyhepta-2, 4-diene-1, 7-dioate
           isomerase related protein; n=3; Archaea|Rep:
           2-hydroxyhepta-2, 4-diene-1, 7-dioate isomerase related
           protein - Thermoplasma acidophilum
          Length = 250

 Score =  140 bits (338), Expect = 5e-32
 Identities = 73/212 (34%), Positives = 123/212 (58%), Gaps = 7/212 (3%)

Query: 78  KILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRIRTDVTKKVDWEVELCVV 137
           KI    +N++ H QE +   PP P  F+KFS+ ++G +       ++ +K+D+E E+ +V
Sbjct: 38  KIFLPAVNFRSHSQESDTKFPPKPYFFTKFSNALVGHNGTAHRPREI-EKLDYEGEIGIV 96

Query: 138 VGREASCVREEDALQHVAGYTVAQDISARDWQ--KEKNMG-QFLLGKSMDTFCPLGPCVL 194
           +G+    +  E+A  ++ G+T+  D+SARD+Q  +    G  ++ GK+ D   P+GP ++
Sbjct: 97  IGKRGKRIGVEEAQNYIFGFTIVDDVSARDYQFPEMHPYGYNWVQGKAFDEALPVGPYIV 156

Query: 195 TSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPGDLILTGTPGG 254
           T DE+     L++   +NG L+QS +T  +V S+  L+  +S  +TL PGDLI TGTP G
Sbjct: 157 TRDEI--RFPLKIETRVNGELRQSGTTEDMVFSVEQLISTVSQTITLEPGDLITTGTPAG 214

Query: 255 VGMYRQPPEYLQPGDVLTSEIEKIGAFDVRIE 286
           V  + +  +YL  GD ++  +  IG    RIE
Sbjct: 215 VAAFTE-AKYLSDGDTVSISVSGIGELVHRIE 245


>UniRef50_A2QL54 Cluster: Contig An05c0060, complete genome; n=6;
           Pezizomycotina|Rep: Contig An05c0060, complete genome -
           Aspergillus niger
          Length = 290

 Score =  139 bits (336), Expect = 9e-32
 Identities = 79/215 (36%), Positives = 116/215 (53%), Gaps = 11/215 (5%)

Query: 79  ILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRIRTDVTKK---VDWEVELC 135
           I C+GLNY DH +E NL  P VP++F+K  S +IGP  P  I      +    D+E ELC
Sbjct: 76  IRCLGLNYIDHAKEANLALPEVPILFTKPRSALIGP-YPASISVPKCAQDGTSDYESELC 134

Query: 136 VVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLLGKSMDTFCPLG----- 190
           VV+GR    + EE+AL +V GYT + D+SAR  Q      Q+   K +D  CP+G     
Sbjct: 135 VVIGRTGRDIPEENALDYVLGYTASNDVSARTLQMAT--AQWSFSKGLDESCPIGIDRTG 192

Query: 191 PCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPGDLILTG 250
           P +++   +     LR+    NGV+ Q   T  ++ SI   +  +S   TL  G + LTG
Sbjct: 193 PVLVSPSVIKDPQTLRIQGIHNGVVVQDGHTKDMIFSIKRQISYLSQGTTLEAGTIFLTG 252

Query: 251 TPGGVGMYRQPPEYLQPGDVLTSEIEKIGAFDVRI 285
           TP G+G ++ P + L+ GD  +  I+KIG    ++
Sbjct: 253 TPAGIGYFKSPRDVLKDGDEFSVYIDKIGTLTNKV 287


>UniRef50_Q74FM1 Cluster: Fumarylacetoacetate hydrolase family
           protein; n=8; Desulfuromonadales|Rep:
           Fumarylacetoacetate hydrolase family protein - Geobacter
           sulfurreducens
          Length = 218

 Score =  138 bits (335), Expect = 1e-31
 Identities = 79/213 (37%), Positives = 122/213 (57%), Gaps = 11/213 (5%)

Query: 76  VDKILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRIRTDVTKKVDWEVELC 135
           + KILCIG NY +H +E     P  P+VF K ++ +IG  + + I +  +++   E EL 
Sbjct: 15  IGKILCIGRNYAEHIKELGNETPDAPVVFMKPATAVIGDGETIIIPS-YSRECHHEAELA 73

Query: 136 VVVGREASCVREEDALQHVAGYTVAQDISARDWQKE-KNMG-QFLLGKSMDTFCPLGPCV 193
           +++G+    +  E AL+HVAGY VA D++ RD Q E K  G  + + K  DT CPL   V
Sbjct: 74  LLIGKGGKDIPPERALEHVAGYGVAIDLTLRDVQAELKKKGLPWEIAKGFDTSCPLSSFV 133

Query: 194 LTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPGDLILTGTPG 253
             +D V    +L ++  +NG ++Q  S++ ++H IP +L  +S V TL PGD+ILTGTP 
Sbjct: 134 -PADRVADPHDLHITLRVNGEMRQDGSSSLMIHRIPQILSYMSGVFTLEPGDVILTGTPA 192

Query: 254 GVGMYRQPPEYLQPGDVLTSEIEKIGAFDVRIE 286
           GVG        L  GD + +E+  + A  V ++
Sbjct: 193 GVGP-------LAAGDAVEAEVVGVAAIRVTVK 218


>UniRef50_Q8TWN0 Cluster: 2-keto-4-pentenoate hydratase hydratase;
           n=1; Methanopyrus kandleri|Rep: 2-keto-4-pentenoate
           hydratase hydratase - Methanopyrus kandleri
          Length = 264

 Score =  138 bits (335), Expect = 1e-31
 Identities = 85/221 (38%), Positives = 126/221 (57%), Gaps = 18/221 (8%)

Query: 63  PLSSVTLTAPIHGVDKILCIGLNYKDHCQE---QNLTPPPVPMVFSKFSSTIIGPDQPVR 119
           PLS + +  P+    KI+C GLNY++H +E     +  P  P++  K  + +IG    V+
Sbjct: 50  PLSELRIGPPVPRPPKIICFGLNYREHVEELREMGMDVPSEPVMTMKAPTAVIGHLDTVK 109

Query: 120 IRTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLL 179
           +  +  ++VD E+EL VV+G     V  E+A   V G+T+  D++ARD +K +  GQ++ 
Sbjct: 110 LPREA-RRVDHELELAVVIGERCRKVSPEEARDAVLGFTIINDVTARDIEKRE--GQWVR 166

Query: 180 GKSMDTFCPLGPCVLTSDEV-GAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSV 238
            KS DTF PLGP + T  E  G  +ELRV    NG ++Q ++T  +V     L+   S V
Sbjct: 167 AKSYDTFAPLGPWIETELEPDGLEMELRV----NGEVRQRATTDDMVRDPYELVSFTSRV 222

Query: 239 MTLVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIG 279
           MTL PGD+I TGTP GVG        ++P D +  EIE+IG
Sbjct: 223 MTLEPGDIIATGTPPGVGP-------MEPDDKIELEIERIG 256


>UniRef50_UPI000038DFF7 Cluster: hypothetical protein Faci_03001459;
           n=1; Ferroplasma acidarmanus fer1|Rep: hypothetical
           protein Faci_03001459 - Ferroplasma acidarmanus fer1
          Length = 274

 Score =  138 bits (334), Expect = 2e-31
 Identities = 90/258 (34%), Positives = 131/258 (50%), Gaps = 13/258 (5%)

Query: 32  DSSLPTTLLQILRNGDLEKVKKLKSTKPATIPLSSVTLTAPIHGVDKILCIGLNYKDHCQ 91
           D  +  T +  L + D  K+K +   +  T   +S+     I     +LCIGLNYK H  
Sbjct: 27  DYGIKATSVAELSHDDFAKLKDINRFQDYTFSYNSI-----IDQKSSLLCIGLNYKSHVS 81

Query: 92  EQ-NLTPPPVPMVFSKFSSTIIGPDQPVRIRTDVTKKVDWEVELCVVVGREASCVREEDA 150
           E      P  P+VFSK ++   G    V+  T     +D+E ELCV++G+ A  V E +A
Sbjct: 82  EHAGGKIPETPVVFSKANNAFTGNHSIVQ--TGNGMHMDYEGELCVMIGKTARNVGEANA 139

Query: 151 LQHVAGYTVAQDISARDWQKEKNMGQFLLGKSMDTFCPLGPCVLTSDEVGAAVELRVSCS 210
           L +V GY +  D+S+R  Q +    QF LGKS D F P GP + +  E+     L +   
Sbjct: 140 LNYVLGYFIGNDVSSRLMQYKTT--QFFLGKSFDNFYPNGPYI-SIGEINDPQNLTIQTR 196

Query: 211 LNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPGDLILTGTPGGV--GMYRQPPEYLQPG 268
           +NG L+Q S+T  ++  +  L+  IS  MTL PGD I TGTP GV  GM     ++L  G
Sbjct: 197 VNGELRQDSNTGLMIFPVNKLISYISQFMTLRPGDCISTGTPAGVIMGMPESNQKWLGKG 256

Query: 269 DVLTSEIEKIGAFDVRIE 286
           D +  +I  +G  +   E
Sbjct: 257 DKVEVQITGLGKLETTFE 274


>UniRef50_Q9KBC3 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate
           isomerase; n=1; Bacillus halodurans|Rep:
           2-hydroxyhepta-2,4-diene-1,7-dioate isomerase - Bacillus
           halodurans
          Length = 276

 Score =  138 bits (334), Expect = 2e-31
 Identities = 90/273 (32%), Positives = 148/273 (54%), Gaps = 16/273 (5%)

Query: 14  NIRVGYLEGDDIVDIN----KADSSLPTTLLQILRNGDLEKVKKLKSTKPATIPLSSVTL 69
           + ++G ++ + I DI+          P TLL I    D +   + +  +  +  L+ V L
Sbjct: 8   DFQLGLVKEEMIYDISLLLPNPTGGCPMTLL-IEHFDDYKTTIEQEYHRQPSYRLNDVRL 66

Query: 70  TAPIHGVDKILCIGLNYKDHCQEQNLTPPP-VPMVFSKFSSTIIGPDQPVRIRTDVTKKV 128
             P+    KI+   +NY  H +E N+     V   F K +++IIGP+ P+ +  +  +++
Sbjct: 67  RQPLSRPGKIVAAPVNYMSHKKEMNVDHTARVLGFFLKATTSIIGPNDPIILPYN-NRRI 125

Query: 129 DWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLLGKSMDTFCP 188
           D E+EL  V+G+ A  V++E+A  ++ GYT   D++ R  +  +   +  L KS DTF P
Sbjct: 126 DHELELAFVIGKRAKHVKKENAHDYIFGYTGLNDVTVRPTKNREE--ERCLRKSFDTFTP 183

Query: 189 LGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPGDLIL 248
           +GP ++TSDE+     L +S  +N  ++Q  +T Q+V  I  L+   S VMTL PGDLI 
Sbjct: 184 IGPWIVTSDEIKDPQNLTISLQVNHEVRQHVNTNQMVCGIAELVEIFSHVMTLEPGDLIA 243

Query: 249 TGTPGGVGMYRQPPEYLQPGDVLTSEIEKIGAF 281
           TGTP GVG        ++ GD +T ++E IG+F
Sbjct: 244 TGTPDGVGP-------IKDGDTVTLQMESIGSF 269


>UniRef50_A7D5S8 Cluster: 5-carboxymethyl-2-hydroxymuconate
           delta-isomerase; n=1; Halorubrum lacusprofundi ATCC
           49239|Rep: 5-carboxymethyl-2-hydroxymuconate
           delta-isomerase - Halorubrum lacusprofundi ATCC 49239
          Length = 304

 Score =  138 bits (334), Expect = 2e-31
 Identities = 85/213 (39%), Positives = 121/213 (56%), Gaps = 20/213 (9%)

Query: 78  KILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRIRTDVTKKVDWEVELCVV 137
           KI+CIG NY DH  E +   P  P++F K  + +      + +      ++DWE E+ VV
Sbjct: 106 KIVCIGRNYADHAAELDNDVPDRPLLFLKPPNALASHGDEITVPAG-KDRIDWEAEIAVV 164

Query: 138 VGREASCVREEDALQHVAGYTVAQDISARDWQ-KEKNMGQFLLGKSMDTFCPLGPCVLTS 196
           +G +   V  +DA+  VAG+T   D+S RD Q +E+N   ++ GK+ D   PLGP + T 
Sbjct: 165 IGEQCKDVDADDAMDVVAGFTCMNDVSNRDDQDREQN---WVRGKAFDGAAPLGPVMATP 221

Query: 197 DEV--GAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPGDLILTGTPGG 254
           DEV   A+VELRV    NG  KQSS  + L+  +P+L+  I++ +TL PGD+I TGTP G
Sbjct: 222 DEVPADASVELRV----NGETKQSSDRSYLMFDVPTLIEEITTYLTLEPGDVISTGTPEG 277

Query: 255 VGMYRQPPEYLQPGDVLTSEIEKIGAF--DVRI 285
           VG        L  GD +  EIE +G    DVR+
Sbjct: 278 VGA-------LSDGDTVEVEIEGVGTLEHDVRV 303


>UniRef50_Q6BTI3 Cluster: Similar to CA3735|IPF5534 Candida albicans
           IPF5534 5-oxo-1; n=1; Debaryomyces hansenii|Rep: Similar
           to CA3735|IPF5534 Candida albicans IPF5534 5-oxo-1 -
           Debaryomyces hansenii (Yeast) (Torulaspora hansenii)
          Length = 289

 Score =  138 bits (333), Expect = 2e-31
 Identities = 78/217 (35%), Positives = 118/217 (54%), Gaps = 9/217 (4%)

Query: 69  LTAPIHGVDK--ILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRIRTDVTK 126
           L  P+ G D   + CIG+NYK+H     + PPP P +F K  +++   ++ + I      
Sbjct: 67  LLGPLTGEDVPVVKCIGMNYKEHLMGI-IEPPPYPQLFYKPRTSVADQNEDIPIPLFAQN 125

Query: 127 KVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQ----KEKNMGQFLLGKS 182
             D+E ELCVV+G+    + EEDAL +VAGY    D+SARDWQ        + Q    KS
Sbjct: 126 TCDYEGELCVVIGKTGKNINEEDALSYVAGYVSGNDLSARDWQYFPEYAGKVPQLGFSKS 185

Query: 183 MDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLV 242
            D + PLGP +++S  +     L++   +NG L+Q+  T  L+  I  ++  IS   TL 
Sbjct: 186 FDRYAPLGPAIVSSKIIKDPHALQLQTRINGDLRQNCGTDDLLFGISRIIAFISQETTLE 245

Query: 243 PGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIG 279
            G +I+TGTP G G      +YL+ GD++   I++IG
Sbjct: 246 QGTVIMTGTPNGCGGI--DGKYLKDGDLVEVTIDQIG 280


>UniRef50_A3EQW7 Cluster: 2-keto-4-pentenoate
           hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase;
           n=1; Leptospirillum sp. Group II UBA|Rep:
           2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic
           acid hydratase - Leptospirillum sp. Group II UBA
          Length = 267

 Score =  137 bits (332), Expect = 3e-31
 Identities = 85/243 (34%), Positives = 137/243 (56%), Gaps = 14/243 (5%)

Query: 38  TLLQILRNGDLEKVKKLKSTKPATIPLSSVTLTAPIHGVDKILCIGLNYKDHCQEQNLTP 97
           TL   + + D  ++  L      +  L  V L  P+    KI+ +GLNY+ H  E     
Sbjct: 21  TLFWGVLSEDGSRLHPLSGPGHGSFSLLDVRLHPPVTP-GKIIAVGLNYRAHGNEMGKPL 79

Query: 98  PPVPMVFSKFSSTIIGPDQPVRIRTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGY 157
           P  P++F K +S ++ P+  +R+   ++++VD+E E+ +V+G++AS +  E+    V G 
Sbjct: 80  PEEPLLFMKATSALLPPNGEIRLPR-MSRRVDFEGEIALVMGKKASGISPEEVPLFVYGI 138

Query: 158 TVAQDISARDWQKEKNMGQFLLGKSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQ 217
           T A D++ARD QK K++ Q+   KS DTFCPLGP +LT        + R+   +NGV++Q
Sbjct: 139 TCANDVTARDLQK-KDV-QYTRAKSFDTFCPLGPVILTG---ALPDDRRLRTEVNGVVRQ 193

Query: 218 SSSTAQLVHSIPSLLHRISSVMTLVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEK 277
            +  + ++    +L+  IS VMTL PGD+ILTGTP GVG        L P D ++  +E 
Sbjct: 194 EARASDMIFDPLTLVSFISQVMTLEPGDVILTGTPSGVGP-------LSPMDRVSVSLEG 246

Query: 278 IGA 280
           +G+
Sbjct: 247 VGS 249


>UniRef50_Q6AFQ8 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate
           isomerase; n=2; Microbacteriaceae|Rep:
           2-hydroxyhepta-2,4-diene-1,7-dioate isomerase -
           Leifsonia xyli subsp. xyli
          Length = 291

 Score =  137 bits (331), Expect = 3e-31
 Identities = 88/270 (32%), Positives = 138/270 (51%), Gaps = 8/270 (2%)

Query: 16  RVGYLEGDDIVDINKADSSLPTTLLQILRNGD--LEKVKKL-KSTKPATIPLSSVTLTAP 72
           R+  + GD  + +++  +  P  L +++  G+  L  V+ L      A  PL+ V     
Sbjct: 15  RLAAVIGDGALFLDEMMAQAPRDLQELIERGEEALTDVRALVNEAVTAKTPLTLVQELRH 74

Query: 73  IHGV---DKILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRIRTDVTKKVD 129
              V    +++ IG NY  H  E  L       VFS + +++ G         D+  +VD
Sbjct: 75  ASAVLRPPQVIAIGANYAAHASELKLRSEKAATVFSLWPNSLAGHGGTTSWPGDLATQVD 134

Query: 130 WEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLLGKSMDTFCPL 189
           +E EL V++G+ A  V  +DAL +V GYTV  DI+ARD Q  +   Q+   KS D F P 
Sbjct: 135 YEAELGVIIGKPARDVLAQDALDYVWGYTVVNDITARDLQFSE--AQWSRCKSFDGFTPN 192

Query: 190 GPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPGDLILT 249
           GP  +T+DEV    +L ++ +++G + Q +STA +V S+  ++  +S   T+  G LI T
Sbjct: 193 GPVAVTADEVPDPQDLWLTTNVDGAILQDASTADMVRSVAEIIEFLSRSATIPAGTLIST 252

Query: 250 GTPGGVGMYRQPPEYLQPGDVLTSEIEKIG 279
           G+PGG G  R PP +L     +T  I  IG
Sbjct: 253 GSPGGAGYSRTPPVFLHDRSTVTVSIGGIG 282


>UniRef50_A0QU69 Cluster: Fumarylacetoacetate hydrolase family
           protein; n=1; Mycobacterium smegmatis str. MC2 155|Rep:
           Fumarylacetoacetate hydrolase family protein -
           Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155)
          Length = 291

 Score =  137 bits (331), Expect = 3e-31
 Identities = 95/286 (33%), Positives = 153/286 (53%), Gaps = 18/286 (6%)

Query: 1   MKLVQFSYKDSPKNIRVGYLEGDDIVDINKADSSLPTTLLQILRNGDLEKVKKLKSTKPA 60
           MKL  F+  D      VG   GD I D+   D+     L+++ R    E  +++  + PA
Sbjct: 1   MKLTTFAAADG--RTVVGIHRGDTI-DVVGVDNM--RELIKLTRGNPAEIERRVTGSVPA 55

Query: 61  TIPLSSVTLTAPIHGVDKILCIGLNYKDHCQEQNL---TPPPVP-MVFSKFSSTIIGPDQ 116
               +   L API     I   G N+K+H  E      +    P +VF +    I+GP+ 
Sbjct: 56  ----AGGRLLAPIKPTKLIHTAG-NFKEHEDESKRVGWSHNVGPWIVFMQNVDAIVGPED 110

Query: 117 PVRIRTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQK-EKNMG 175
            +R    +TK++D+E+EL VV+ ++      EDA+ +VAGY +  D++ARD Q+ E   G
Sbjct: 111 GIRYPDHLTKELDYELELSVVINQDVGEFAPEDAMNYVAGYVIFNDVTARDIQRDEMKSG 170

Query: 176 QFLLGKSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRI 235
            F   K +D+FCP+GP ++T+DE+    +L++   +NG  +Q S ++++  +IP +L R 
Sbjct: 171 VFGFCKGIDSFCPIGPWIVTADEIPNPHDLKMELRVNGEPRQESHSSRMWTTIPEILARY 230

Query: 236 SSVMTLVPGDLILTGTPGGVGMYRQPPE--YLQPGDVLTSEIEKIG 279
           S  +    GD++ TGT  GV  +R   E  YL+ GD +  E+EKIG
Sbjct: 231 SP-LGYSAGDIVTTGTVSGVAGFRVDAEDYYLRVGDSVECEVEKIG 275


>UniRef50_Q2USU7 Cluster: RIB40 genomic DNA, SC005; n=6;
           Pezizomycotina|Rep: RIB40 genomic DNA, SC005 -
           Aspergillus oryzae
          Length = 299

 Score =  137 bits (331), Expect = 3e-31
 Identities = 72/206 (34%), Positives = 116/206 (56%), Gaps = 7/206 (3%)

Query: 81  CIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRI-RTDVTKKVDWEVELCVVVG 139
           C+GLNY  H +E    PPP P +F K ++ +    +PV I R     + D+E ELC+++G
Sbjct: 85  CVGLNYAKHIKEAGRKPPPFPFIFFKPNTCVHDHGKPVVIPRIAQNDQADYEGELCLIIG 144

Query: 140 REASCVREEDALQHVAGYTVAQDISARDWQKEKNMG----QFLLGKSMDTFCPLGPCVLT 195
           ++A  V  E AL++VA YT   DIS+R  Q++        Q+   K  DTF PLGP ++ 
Sbjct: 145 KDAKDVSPEHALEYVAAYTAGNDISSRKLQRDPAYAGVVPQWGFSKGFDTFAPLGPVLVA 204

Query: 196 SDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPGDLILTGTPGGV 255
           + E+    +L +   ++G ++Q  +   L+     L+  +S   TL  G +I+TGTPGG+
Sbjct: 205 ASEIPDPSQLHLKTIVDGEVRQDETVGDLLFDCKYLISYLSQGTTLQKGSVIMTGTPGGL 264

Query: 256 GMYR--QPPEYLQPGDVLTSEIEKIG 279
           G+    +PP++L PG  +  +I +IG
Sbjct: 265 GVGAGFKPPKWLVPGTQMDVQISQIG 290


>UniRef50_Q7BRJ5 Cluster: DitM; n=5; Proteobacteria|Rep: DitM -
           Pseudomonas abietaniphila
          Length = 289

 Score =  136 bits (328), Expect = 8e-31
 Identities = 83/222 (37%), Positives = 122/222 (54%), Gaps = 9/222 (4%)

Query: 62  IPLSSVTLTAPIHGVDKILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRIR 121
           + LS VTL  PI  V++++  G NY  H  E  L+ P  P+ F K    +IG   P+R  
Sbjct: 55  LALSQVTLLPPIEPVNRVVVAGANYAKHLVEFGLSAPSQPVAFLKAYGALIGAHDPIRF- 113

Query: 122 TDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKE--KNMGQFLL 179
             +T ++D EVEL  V+G +   V  +D L  V GYTV  D+SARD Q+   K +G  L 
Sbjct: 114 PPLTTELDHEVELVAVIGSDD--VDLDDPLACVLGYTVGNDVSARDLQRSGPKGIGMDLF 171

Query: 180 -GKSMDTFCPLGPCVLTSDEV-GAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISS 237
             KS D    LGP V+T DE+   + +LR++  +NG ++Q  +TA +   +  L+  +  
Sbjct: 172 AAKSQDKTTGLGPWVVTKDELPEGSPKLRLTLKVNGQMRQDGNTADMTWDVGELIAFVQQ 231

Query: 238 VMTLVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIG 279
             +   GD++ TG+P GVGM      +L PGDV+ + IE IG
Sbjct: 232 RSSFACGDVLFTGSPAGVGM--GTGIFLDPGDVVEASIEGIG 271


>UniRef50_Q09C56 Cluster: Fumarylacetoacetate hydrolase family
           protein; n=2; Cystobacterineae|Rep: Fumarylacetoacetate
           hydrolase family protein - Stigmatella aurantiaca
           DW4/3-1
          Length = 257

 Score =  136 bits (328), Expect = 8e-31
 Identities = 81/223 (36%), Positives = 123/223 (55%), Gaps = 14/223 (6%)

Query: 64  LSSVTLTAPIHGVDKILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRIRTD 123
           LSS+TL  P     K++CIG NY+ H +E     P  P++F K S+ + GP  P+R+   
Sbjct: 46  LSSLTLLVPSEA-SKVVCIGQNYRKHAEEMGKPVPSEPLLFIKPSTALNGPRSPIRL-PK 103

Query: 124 VTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLLGKSM 183
            +++V +E EL +V+G       E  A + + G T   D++ARD Q+ +   Q    KS 
Sbjct: 104 ASQEVHYEAELGLVIGERLKNADEATAARAIWGLTCINDVTARDIQRREV--QHTRAKSY 161

Query: 184 DTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVP 243
           DTF  +GP  +T     +  +LR+ C +NG ++Q S T+ +V +   L+  IS +MTL+P
Sbjct: 162 DTFACVGPWAVTGL---SPADLRILCRVNGQVRQDSRTSDMVFNPAQLVSFISHIMTLLP 218

Query: 244 GDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIGAFDVRIE 286
           GDL+ TGTP GVG        L  GD++  E+E IG     +E
Sbjct: 219 GDLVSTGTPSGVGA-------LAAGDMVEVELEGIGTLANPVE 254


>UniRef50_Q1MQ53 Cluster: 2-keto-4-pentenoate
           hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase;
           n=1; Lawsonia intracellularis PHE/MN1-00|Rep:
           2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic
           acid hydratase - Lawsonia intracellularis (strain
           PHE/MN1-00)
          Length = 257

 Score =  135 bits (327), Expect = 1e-30
 Identities = 82/227 (36%), Positives = 128/227 (56%), Gaps = 13/227 (5%)

Query: 62  IPLSSVTLTAPIHGVDKILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRIR 121
           IPLS + +  P+    KI+CI +NY +  QE     P  P  F K  S+I+G  QP+ + 
Sbjct: 36  IPLSKIKVL-PLVSPTKIICIDINYHEKAQELQQPIPTNPTFFFKPPSSIVGNGQPILLP 94

Query: 122 TDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLLGK 181
           T++ + V  E ELC+V+G+    V  E A  ++ GYT A DI+A+D Q+++        K
Sbjct: 95  TNIGRVVS-EAELCIVIGQTCYKVTPEAASNYIFGYTCANDITAKDIQQQEYTTSH--AK 151

Query: 182 SMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTL 241
           + +TFCP+GP + T  +V     L++  S+N  L Q S+TA ++     L+  +S++MTL
Sbjct: 152 AYNTFCPVGPWIET--DVPNIENLQIRNSINSELGQVSTTADMIFPPLELISFLSNIMTL 209

Query: 242 VPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIGAFDVRIEKF 288
            PGDLILTGTP G  +       +  GD++ + IE +G     IE++
Sbjct: 210 NPGDLILTGTPKGSLL-------ISDGDIVQTSIENVGILINPIEEY 249


>UniRef50_Q9RYT2 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate
           isomerase/5-carboxymethyl-2-oxo- hex-3-ene-1,7-dioate
           decarboxylase; n=4; Deinococci|Rep:
           2-hydroxyhepta-2,4-diene-1,7-dioate
           isomerase/5-carboxymethyl-2-oxo- hex-3-ene-1,7-dioate
           decarboxylase - Deinococcus radiodurans
          Length = 262

 Score =  134 bits (325), Expect = 2e-30
 Identities = 76/205 (37%), Positives = 116/205 (56%), Gaps = 9/205 (4%)

Query: 78  KILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRIRTDVTKKVDWEVELCVV 137
           K++ + LNY DH  E     P  P++F K +++++ P Q   I     K + +EVEL +V
Sbjct: 46  KVIALALNYADHVAELGFKAPEEPVMFLKPNTSLL-PHQGTVIYPRGAKFMHYEVELGIV 104

Query: 138 VGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLLGKSMDTFCPLGPCVLTSD 197
           +GR+A  V+ +DA  +V GYT+A D+  RD+         +  K  DTF PLGP ++++D
Sbjct: 105 IGRDARRVKAKDADDYVGGYTIANDLVVRDYVSNYYRPP-MRAKGWDTFGPLGPYLVSAD 163

Query: 198 EVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPGDLILTGTPGGVGM 257
           EV     L +   +NG L+Q  ST  ++   P L+  +S  MTL  GD+ILTGTP GV  
Sbjct: 164 EVPDPYNLGLRAYVNGELRQEGSTRDMILKAPELIEFMSRFMTLEAGDVILTGTPKGV-- 221

Query: 258 YRQPPEYLQPGDVLTSEIEKIGAFD 282
                 ++ PGDV+  EI+ +GA +
Sbjct: 222 -----SHVHPGDVMRLEIDGLGALE 241


>UniRef50_Q6BTK5 Cluster: Similar to CA3735|IPF5534 Candida albicans
           IPF5534; n=2; Ascomycota|Rep: Similar to CA3735|IPF5534
           Candida albicans IPF5534 - Debaryomyces hansenii (Yeast)
           (Torulaspora hansenii)
          Length = 208

 Score =  134 bits (324), Expect = 2e-30
 Identities = 73/207 (35%), Positives = 116/207 (56%), Gaps = 7/207 (3%)

Query: 84  LNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRI-RTDVTKKVDWEVELCVVVGREA 142
           +NY  H QE +L PPP P +F K  +++   ++ + I +     + D+E E CVV+ +  
Sbjct: 1   MNYMKHIQEGSLPPPPKPQIFYKPRTSVGDHNEAIAIPKIAQENQCDYEGEFCVVIVKTG 60

Query: 143 SCVREEDALQHVAGYTVAQDISARDWQKEK----NMGQFLLGKSMDTFCPLGPCVLTSDE 198
             ++EEDAL +VAGY V  D+SAR WQ       N+ Q+   KS D + PLGP + ++  
Sbjct: 61  KHIKEEDALNYVAGYIVGDDVSARIWQYHPDYSGNIPQWYYSKSFDRYAPLGPALFSTRV 120

Query: 199 VGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPGDLILTGTPGGVGMY 258
           +     L++   +NG L+Q ++T  L+ +I  ++  +S   TL  G +I+TGTP GVG  
Sbjct: 121 IKNPHTLQLQTRINGELRQDANTDDLLFNIQKIIAFLSQGTTLEQGTVIMTGTPSGVGAV 180

Query: 259 RQPPEYLQPGDVLTSEIEKIGAFDVRI 285
                YL+ GD++   IE+IG    +I
Sbjct: 181 --SGRYLKDGDLVEISIEQIGTLSHKI 205


>UniRef50_Q5KN08 Cluster: Mitochondrion protein, putative; n=14;
           Dikarya|Rep: Mitochondrion protein, putative -
           Cryptococcus neoformans (Filobasidiella neoformans)
          Length = 311

 Score =  134 bits (324), Expect = 2e-30
 Identities = 73/197 (37%), Positives = 112/197 (56%), Gaps = 5/197 (2%)

Query: 76  VDKILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGP-DQPVRIRTD--VTKKVDWEV 132
           V  I CIGLNY +H +E NL  P +P +F K S+++  P   P  I      +   D+E 
Sbjct: 96  VGTIRCIGLNYVNHAKEVNLPMPDIPTLFMKPSTSLADPFPSPTIIPKAFVASNSADFES 155

Query: 133 ELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLLGKSMDTFCPLGPC 192
           E+  V+G++A  V EE+AL +V G+T A D+S+R+ Q  ++  Q+   KS D  CP+GP 
Sbjct: 156 EVAFVIGKDAKNVSEEEALDYVLGFTAANDVSSREAQFAQS--QWCYSKSFDGACPIGPA 213

Query: 193 VLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPGDLILTGTP 252
           ++  ++     ++++  SLNG   QSS    L+ S+P ++  +S   TL  G +I+TGTP
Sbjct: 214 LVNKNQANKFSDVKIEGSLNGKTVQSSRLDDLIFSVPKIVSFLSQGTTLPAGTIIITGTP 273

Query: 253 GGVGMYRQPPEYLQPGD 269
            GVG    P   L+ GD
Sbjct: 274 AGVGWSSTPRITLKDGD 290


>UniRef50_Q11E65 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=1;
           Mesorhizobium sp. BNC1|Rep: Fumarylacetoacetate (FAA)
           hydrolase - Mesorhizobium sp. (strain BNC1)
          Length = 307

 Score =  133 bits (322), Expect = 4e-30
 Identities = 100/307 (32%), Positives = 152/307 (49%), Gaps = 38/307 (12%)

Query: 1   MKLVQFSYKDSPKNIRVGYLEGD---DIVDIN--KADSSLPTTLLQILRNGDLEKVKKLK 55
           +KLV +S    P+ IR   ++ D   D  D+    A +S+P  L           ++   
Sbjct: 4   LKLVSYS---GPRGIRTAAVKADRYVDAADVTGVAAHASMPGLLADWAAAE--RPLQAAF 58

Query: 56  STKPATIPLSSVTLTAPIHGVDKILCIGLNYKDHCQE----------------QNLTPPP 99
           +   A + L  +    P+ G   I CIG NY DH  E                Q      
Sbjct: 59  AAGQAMVGLPKLVAPLPLPGA--IYCIGANYADHIAEMQGGGTNGASVAAERKQQKEDGL 116

Query: 100 VPMVFSKFSSTIIGPDQPVRIRTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTV 159
            P  F K S ++ GP+  V +    +KKVDWE EL VV+GR++  +  E+AL  V GYT+
Sbjct: 117 KPWFFIKSSHSVCGPETKVALPA-TSKKVDWEAELAVVIGRKSRDLTIENALTAVWGYTI 175

Query: 160 AQDISARDWQKEKNMGQ-------FLLGKSMDTFCPLGPCVLTSDEVGAAVELRVSCSLN 212
           A D+SARD  +   + Q       +   KS D  CP+GP ++++ ++  A +L +  S+N
Sbjct: 176 ANDLSARDLSRRPPLPQGSPFFFDWTSHKSFDDSCPMGPWIVSASQIVDANDLDIGLSIN 235

Query: 213 GVLKQSSSTAQLVHSIPSLLHRISSVMTLVPGDLILTGTPGGVGMYRQPPEYLQPGDVLT 272
           G   Q S+T+Q++ ++   +  +S  +TL PGD+ILTGTP GVG  R     L+P D ++
Sbjct: 236 GQPMQKSNTSQMIFTVAEQVAHLSQRITLWPGDIILTGTPAGVGAGRNLS--LKPSDEVS 293

Query: 273 SEIEKIG 279
             IE IG
Sbjct: 294 VYIEGIG 300


>UniRef50_Q5KZR6 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate
           isomerase; n=3; Bacillaceae|Rep:
           2-hydroxyhepta-2,4-diene-1,7-dioate isomerase -
           Geobacillus kaustophilus
          Length = 262

 Score =  133 bits (321), Expect = 6e-30
 Identities = 84/214 (39%), Positives = 125/214 (58%), Gaps = 16/214 (7%)

Query: 67  VTLTAPIHGVDKILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRIRTDVTK 126
           V+L AP+     ++ IG NY    ++  +  P +P+ F K SS+++GP+  V I + V +
Sbjct: 45  VSLVAPL-APRHVIGIGANYVASSEQLPVELPDIPVFFFKPSSSVVGPEAEVVIPSGVGE 103

Query: 127 KVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLLGKSMDTF 186
            V +E EL VV+G+EA  V EED   ++ GYTVA D++A  +      G + +GKS DTF
Sbjct: 104 -VKFESELAVVIGKEAKQVSEEDVWSYIFGYTVANDVTAPQFFHPD--GHWTIGKSFDTF 160

Query: 187 CPLGPCVLTS-DEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPGD 245
            PLGP + T  D    +V+ RV    NG  KQ+SST  ++ SI  ++  +S VMTL PGD
Sbjct: 161 TPLGPVIETELDPRAVSVKARV----NGEEKQNSSTKLMIISISKMISYLSHVMTLQPGD 216

Query: 246 LILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIG 279
           +ILTG+P G        E + PG V+  +++ IG
Sbjct: 217 VILTGSPVGA-------ELVGPGTVIECDVDGIG 243


>UniRef50_Q28U26 Cluster: 5-carboxymethyl-2-hydroxymuconate
           delta-isomerase; n=1; Jannaschia sp. CCS1|Rep:
           5-carboxymethyl-2-hydroxymuconate delta-isomerase -
           Jannaschia sp. (strain CCS1)
          Length = 271

 Score =  132 bits (320), Expect = 8e-30
 Identities = 78/217 (35%), Positives = 116/217 (53%), Gaps = 12/217 (5%)

Query: 67  VTLTAPIHGVDKILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRIRTDVTK 126
           VT   P+    KILC+ LNY DH +E N   P  P+VF K    +I    P+R    +T+
Sbjct: 48  VTALPPVTPTAKILCVALNYVDHAKEANQPVPETPIVFFKTFDAMIAGGAPIRAPRMITQ 107

Query: 127 KVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMG----QFLLGKS 182
            +D+E EL +++G+    + + DA  H+AG T   D+SARD  K K        +  GK 
Sbjct: 108 -LDYEGELALIIGKRGFDIAKTDAWDHIAGVTTLNDVSARDIFKVKAGAASHLDWFSGKC 166

Query: 183 MDTFCPLGPCVLT----SDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSV 238
           ++   P+GP V       D++ A    R+ C +NG ++Q +  A ++  IP+++  ISS 
Sbjct: 167 LNQSTPIGPEVFPLSAIEDDLKAGTT-RIRCLVNGEVRQDAPVADMIFDIPTMIAFISSR 225

Query: 239 MTLVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEI 275
           + L PGD+I TGTP GVG       YL  GDV+  E+
Sbjct: 226 IPLNPGDIIATGTPPGVG--AGTDRYLSKGDVVRVEV 260


>UniRef50_A3YN46 Cluster: Fumarylacetoacetate hydrolase family
           protein; n=13; Campylobacter|Rep: Fumarylacetoacetate
           hydrolase family protein - Campylobacter jejuni subsp.
           jejuni CF93-6
          Length = 292

 Score =  132 bits (320), Expect = 8e-30
 Identities = 89/288 (30%), Positives = 140/288 (48%), Gaps = 16/288 (5%)

Query: 1   MKLVQFSYKDSPKNIRVGYLEGDDIVDINKADSSLPTT-LLQILRNGD--LEKVKKLKST 57
           MK V F +    +   +G       V +N AD  +    + +++ N D    K K L S 
Sbjct: 1   MKFVNFKFN---QKATLGVFNSSGKV-VNLADLDINVRDMNELIINFDEFKHKFKDLDSK 56

Query: 58  KPATIPLSSVTLTAPIHGVDKILCIGLNYKDHCQE------QNLTPPPVPMVFSKFSSTI 111
               IP     L   I     I+C+G+N+ DH +E      +       P+ F K  +  
Sbjct: 57  TAYEIPKEDY-LAPIIEPRQDIICLGINFLDHAKESAQFKGEKFEEREYPVYFGKRCNQA 115

Query: 112 IGPDQPVRIRTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKE 171
             P   + +  DVT ++D+E EL  ++ ++A  ++ EDA  ++ GYT+  +ISARD QK 
Sbjct: 116 TAPFGSISLHADVTSQLDYECELAFILSKDAYKIKAEDAKDYIFGYTIINEISARDLQKR 175

Query: 172 KNMGQFLLGKSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSL 231
               QF   KS++    +GP + + DE+    EL +   +N  L+Q+S+T   +  I  +
Sbjct: 176 HK--QFYRAKSLEGSTIMGPYITSVDEIAYPPELHLKSYVNKELRQNSNTKFFIFDIGYV 233

Query: 232 LHRISSVMTLVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIG 279
           L  +SS M L  G +I  GTP GVGM   PP +L+ GD +   IE +G
Sbjct: 234 LEELSSGMLLKAGTIISMGTPSGVGMGLNPPVFLKKGDEVRCVIENLG 281


>UniRef50_Q4JXJ3 Cluster: Putative
           2-hydroxyhepta-2,4-diene-1,7-dioate isomerase; n=1;
           Corynebacterium jeikeium K411|Rep: Putative
           2-hydroxyhepta-2,4-diene-1,7-dioate isomerase -
           Corynebacterium jeikeium (strain K411)
          Length = 272

 Score =  132 bits (319), Expect = 1e-29
 Identities = 83/238 (34%), Positives = 124/238 (52%), Gaps = 16/238 (6%)

Query: 52  KKLKSTKPATIPLSSVT---LTAPIHGVDKILCIGLNYKDHCQEQNLTPPPVPMVFSKFS 108
           +++ ST+  ++P  S T   L   +    KI C+GLNY++H  E     P  P +F K++
Sbjct: 45  EQVTSTELDSLPTVSFTADQLGPVVPNPGKIFCVGLNYREHIAEMGHPIPDHPTLFVKYA 104

Query: 109 STIIGPDQPVRIRTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDW 168
           S + GP   V +  +++ + D+E EL V++G              +AGYTV  D S RDW
Sbjct: 105 SALAGPFDEVVVPPELSAQADYEGELAVIMGE----------FGQIAGYTVMNDFSQRDW 154

Query: 169 QKEKNMGQFLLGKSMDTFCPLGPCVLTSDEVGAAVELRVSCS-LNGVLKQSSSTAQLVHS 227
           Q      Q+L GK++D     GP ++ ++      E  V  + +NG L+Q  S A LV  
Sbjct: 155 QYRTQ--QWLQGKNLDRSSGFGPWMVPTEHFDPIAEGAVLRTWVNGELRQEHSVADLVFK 212

Query: 228 IPSLLHRISSVMTLVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIGAFDVRI 285
              L+  IS+  +L PGD+I+TGTP GVG    PP+YL  GD +   I+ IG    RI
Sbjct: 213 PQDLVDYISNFASLAPGDVIVTGTPEGVGHGMTPPQYLADGDEVRIAIDGIGEICNRI 270


>UniRef50_A4SYL9 Cluster: 5-carboxymethyl-2-hydroxymuconate
           Delta-isomerase; n=1; Polynucleobacter sp.
           QLW-P1DMWA-1|Rep: 5-carboxymethyl-2-hydroxymuconate
           Delta-isomerase - Polynucleobacter sp. QLW-P1DMWA-1
          Length = 309

 Score =  132 bits (319), Expect = 1e-29
 Identities = 84/266 (31%), Positives = 138/266 (51%), Gaps = 18/266 (6%)

Query: 36  PTTLLQILRNGDLEKVKKLKSTKPAT-------IPLSSVTLTAPIHGVDKILCIGLNYKD 88
           P+ +   LR+GD E + + KS   +        +  +++T   PI   DK LC+G NY+ 
Sbjct: 44  PSDMKTFLRSGD-EVMNQAKSWVASNGDHSDLLLDANTITYLPPIMDADKFLCVGKNYRT 102

Query: 89  HCQEQNLTP-----PPVPMVFSKFSSTIIGPDQPVRIRTDVTKKVDWEVELCVVVGREAS 143
           H +E   T      P  P  F K +S + G +  V +R     K+D+E EL  V+G+ A 
Sbjct: 103 HLEELKRTNLIKEIPQEPTSFIKLNSCLSGHNATV-VRPKGITKLDYEPELVFVMGKRAL 161

Query: 144 CVREEDALQHVAGYTVAQDISARDWQ-KEKNMG-QFLLGKSMDTFCPLGPCVLTSDEVGA 201
             ++ +A+ ++ G T+  D++ RD Q +E   G +F  GK++  F PLGP ++T DE+  
Sbjct: 162 GAKKSEAMDYIGGVTILNDLTCRDLQLREVASGSRFWTGKNIPGFGPLGPEIITIDEIPN 221

Query: 202 AVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPGDLILTGTPGGVGMYRQP 261
             +L ++CS+NG  +   +T   +  I  +L   S  + +  GD+  TG PGGV + ++ 
Sbjct: 222 PYDLWMTCSVNGEERMRVNTQDQIWKISDILEHFSRFIPIEAGDMFSTGAPGGVAVGKEN 281

Query: 262 PE--YLQPGDVLTSEIEKIGAFDVRI 285
            E  YL+PGDV+   I+ I      I
Sbjct: 282 AEALYLKPGDVVECAIDGISTLRTTI 307


>UniRef50_Q11D77 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=3;
           Proteobacteria|Rep: Fumarylacetoacetate (FAA) hydrolase
           - Mesorhizobium sp. (strain BNC1)
          Length = 293

 Score =  132 bits (318), Expect = 1e-29
 Identities = 89/277 (32%), Positives = 141/277 (50%), Gaps = 26/277 (9%)

Query: 16  RVGYLEGDDIVDINKAD-----SSLPTTLLQILRNGD-LEKVKKLKSTKPATIPLSSVTL 69
           R+G + GD IVD+  A      S  P  ++Q++ N + L    + +       PL+SV L
Sbjct: 10  RIGVVSGDRIVDVTPAAGVDPASWPPVGMVQVIANFERLRATFQHQLDAGGGKPLASVRL 69

Query: 70  TAPIHGVDKILCIGLNYKDHCQEQNLTPPPVPMV-------FSKFSSTIIGPDQPVRIRT 122
             PI   +K++    NY  H  E       +          F K +S++ GP  P+ +  
Sbjct: 70  ECPIAWPNKVVAFPANYHAHIDEMKAGSGLISNFAAAGQGFFLKANSSLSGPADPIVLPN 129

Query: 123 DVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLLGKS 182
              ++V  E EL V++G+    +  E+ALQHV GY+   D   R   KE+ +    + KS
Sbjct: 130 LDGREVHHESELAVIIGKRGRNIPRENALQHVFGYSCLIDAVVRG--KEERV----MRKS 183

Query: 183 MDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLV 242
            DTFCPLGP ++T++EV     + +  ++NG ++Q ++T  L+  +P ++   SSVMTL 
Sbjct: 184 YDTFCPLGPWLVTAEEVPDPANIDIELTVNGEVRQKANTRALIVDVPEMIAMASSVMTLE 243

Query: 243 PGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIG 279
           PGD+I +GTP GVG        + PGD +   I  +G
Sbjct: 244 PGDIIASGTPSGVGP-------MLPGDAVCITIAGVG 273


>UniRef50_Q01DJ4 Cluster: Predicted fumarylacetoacetate hydralase;
           n=2; Ostreococcus|Rep: Predicted fumarylacetoacetate
           hydralase - Ostreococcus tauri
          Length = 322

 Score =  132 bits (318), Expect = 1e-29
 Identities = 86/242 (35%), Positives = 128/242 (52%), Gaps = 18/242 (7%)

Query: 52  KKLKSTKPATIPLSSVTLTAPIHGVDKILCIGLNYKDHCQEQNLTPPPV--------PMV 103
           + L+     + PL    L   +     I C+G NY +H  E + T P +        P++
Sbjct: 75  RSLRVDASLSTPLEECELLCAVDRDVTIACVGKNYLEHVGEVDSTMPGISRMDVPEAPII 134

Query: 104 FSKFSSTIIGPDQPVRIRTDVTKKVDWEVELCVVVGREASCV----REEDALQ-HVAGYT 158
           FSK S+++        I T   K VD+E EL  V+GRE   +     +ED ++ +V G++
Sbjct: 135 FSKASTSLNA--HLGSIATRGRKDVDYEGELVAVIGRECRDIDPGMSDEDVVKNYVIGWS 192

Query: 159 VAQDISARDWQKEKNMGQFLLGKSMDTFCPLGPCVLTSDEVGAAV-ELRVSCSLNGVLKQ 217
           +A D++AR+ QK     Q+ LGKS DT CPLGP V   D    A+    ++ ++N  ++Q
Sbjct: 193 IANDVTARELQKTHQ--QWFLGKSGDTHCPLGPWVCCDDGRAPALGAASITTAVNSEIRQ 250

Query: 218 SSSTAQLVHSIPSLLHRISSVMTLVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEK 277
            S+  QL+ S+ +L+  IS   TL  GD +LTGTP GVG    PP +LQPGD     IE 
Sbjct: 251 RSTVDQLIWSVGALIACISRHQTLRVGDCVLTGTPSGVGAGFDPPRFLQPGDACEVTIEG 310

Query: 278 IG 279
           +G
Sbjct: 311 VG 312


>UniRef50_Q2NHN7 Cluster: Predicted 2-keto-4-pentenoate
           hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase;
           n=1; Methanosphaera stadtmanae DSM 3091|Rep: Predicted
           2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic
           acid hydratase - Methanosphaera stadtmanae (strain DSM
           3091)
          Length = 256

 Score =  132 bits (318), Expect = 1e-29
 Identities = 77/203 (37%), Positives = 121/203 (59%), Gaps = 16/203 (7%)

Query: 78  KILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRIRTDVTKKVDWEVELCVV 137
           KI+C+GLNYKDH +E N+  P  P++F K S+++I  +  + I    T  +D+E EL +V
Sbjct: 64  KIVCVGLNYKDHAKELNMELPDEPLLFMKPSTSVISTNSAI-IYPSTTNMLDFEGELGIV 122

Query: 138 VGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLLGKSMDTFCPLGPCVLTSD 197
           +  + S    ++   +VA YT+  D++ARD Q +   GQ+   KS DTFCP GP V+T  
Sbjct: 123 ILEKVSPC--DNGTCNVA-YTIVNDVTARDLQSKD--GQWTRSKSYDTFCPCGPVVVTGI 177

Query: 198 EVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPGDLILTGTPGGVGM 257
           +   +  L +   +N  +KQ S+T  ++ S   L+  IS++MTL PGD+I +GTP GVG 
Sbjct: 178 D---SSNLNIKTMVNNDIKQESNTKNMIFSPLELVKYISNIMTLNPGDIIASGTPPGVG- 233

Query: 258 YRQPPEYLQPGDVLTSEIEKIGA 280
                 +L  GD +  EI+++G+
Sbjct: 234 ------HLDVGDTVVVEIDEMGS 250


>UniRef50_Q46978 Cluster: 4-hydroxyphenylacetate degradation
           bifunctional isomerase/decarboxylase [Includes:
           2-hydroxyhepta-2,4-diene-1,7-dioate isomerase (EC
           5.3.3.10) (HHDD isomerase) (5-carboxymethyl-2-
           hydroxymuconate Delta-isomerase);
           5-carboxymethyl-2-oxo-hex-3-ene-1,7- dioate
           decarboxylase (EC 4.1.1.68) (5-oxopent-3-ene-1,2,5-
           tricarboxylate decarboxylase) (OPET decarboxylase)];
           n=42; Proteobacteria|Rep: 4-hydroxyphenylacetate
           degradation bifunctional isomerase/decarboxylase
           [Includes: 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase
           (EC 5.3.3.10) (HHDD isomerase) (5-carboxymethyl-2-
           hydroxymuconate Delta-isomerase);
           5-carboxymethyl-2-oxo-hex-3-ene-1,7- dioate
           decarboxylase (EC 4.1.1.68) (5-oxopent-3-ene-1,2,5-
           tricarboxylate decarboxylase) (OPET decarboxylase)] -
           Escherichia coli
          Length = 429

 Score =  132 bits (318), Expect = 1e-29
 Identities = 85/250 (34%), Positives = 127/250 (50%), Gaps = 12/250 (4%)

Query: 36  PTTLLQILRNGDLEKVKKLKSTKPATIPLSSVTLTAPIHGVDKILCIGLNYKDHCQEQNL 95
           P   +++L  G       +   +  T   S  TL  P HG   +  +GLNY DH  E   
Sbjct: 185 PGDRVRVLAEGFPPLENPVVDEREVTTRKSFPTLPHP-HGT--LFALGLNYADHASELEF 241

Query: 96  TPPPVPMVFSKFSSTIIGPDQPVRIRTDVTKKVDWEVELCVVVGREASCVREEDALQHVA 155
            PP  P+VF K  +T+ G +Q   +R +  + + +E EL VV+G++A  V E DA+ +VA
Sbjct: 242 KPPEEPLVFLKAPNTLTGDNQ-TSVRPNNIEYMHYEAELVVVIGKQARNVSEADAMDYVA 300

Query: 156 GYTVAQDISARDWQKEKNMGQFLLGKSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVL 215
           GYTV  D + RD+  E      L  KS D   P+   ++  + +     L +   +NG L
Sbjct: 301 GYTVCNDYAIRDYL-ENYYRPNLRVKSRDGLTPMLSTIVPKEAIPDPHNLTLRTFVNGEL 359

Query: 216 KQSSSTAQLVHSIPSLLHRISSVMTLVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEI 275
           +Q  +TA L+ S+P L+  +S  MTL PGD+I TGTP G+         + PGD +  E+
Sbjct: 360 RQQGTTADLIFSVPFLIAYLSEFMTLNPGDMIATGTPKGL-------SDVVPGDEVVVEV 412

Query: 276 EKIGAFDVRI 285
           E +G    RI
Sbjct: 413 EGVGRLVNRI 422



 Score = 80.2 bits (189), Expect = 6e-14
 Identities = 58/173 (33%), Positives = 84/173 (48%), Gaps = 16/173 (9%)

Query: 97  PPPVPMVFSKFSSTIIGPDQPVRIRTDVTKKVDWEVELCVVVGREASCVREEDALQHVAG 156
           PP   + F K  +T+IG  +P+       +KV     + ++VG+ A+ VREEDA +++AG
Sbjct: 31  PPKTAVWFIKPRNTVIGCGEPIPFPQG--EKVLSGATVALIVGKTATKVREEDAAEYIAG 88

Query: 157 YTVAQDISARDWQKEKNMGQFLLGKSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLK 216
           Y +A D+S     +E      +  K  D FCP+G  V  S+       L +   +NG   
Sbjct: 89  YALANDVSL---PEESFYRPAIKAKCRDGFCPIGETVALSN----VDNLTIYTEINGRPA 141

Query: 217 QSSSTAQLVHSIPSLLHRISSVMTLVPGDLILTGTPGGVGMYRQPPEYLQPGD 269
              +TA L  +   LL  +S   TL PGD IL GTP       Q    +QPGD
Sbjct: 142 DHWNTADLQRNAAQLLSALSEFATLNPGDAILLGTP-------QARVEIQPGD 187


>UniRef50_Q2S2N6 Cluster: Possible
           2-hydroxyhepta-2,4-diene-1,7-dioate isomerase; n=1;
           Salinibacter ruber DSM 13855|Rep: Possible
           2-hydroxyhepta-2,4-diene-1,7-dioate isomerase -
           Salinibacter ruber (strain DSM 13855)
          Length = 220

 Score =  131 bits (317), Expect = 2e-29
 Identities = 74/188 (39%), Positives = 103/188 (54%), Gaps = 4/188 (2%)

Query: 71  APIHGVDKILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRIRTDVTKKVDW 130
           +P   V K+LCIG NY DH  E +   P  PMVF K +S ++     VR+    ++ V  
Sbjct: 9   SPPVSVGKLLCIGRNYADHAAEMDRAVPDEPMVFLKPASALVRSGGAVRLPPQ-SQDVHH 67

Query: 131 EVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKE--KNMGQFLLGKSMDTFCP 188
           EVEL  VVG E   +    AL HVAGY V  D++ARD Q E  +    + + K  DTF P
Sbjct: 68  EVELVAVVGTEGKNIPRSAALDHVAGYAVGLDMTARDLQAEAKERRHPWSVAKGFDTFAP 127

Query: 189 LGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPGDLIL 248
           LGP +  ++ V    +L +  ++N   +Q +ST   +  +  L+H  S + TL PGDL+ 
Sbjct: 128 LGP-IQPAEAVDDVQDLTLRLTVNDETRQEASTRHQIFPVRDLVHYCSHIFTLSPGDLLY 186

Query: 249 TGTPGGVG 256
           TGTP GVG
Sbjct: 187 TGTPSGVG 194


>UniRef50_A2QFQ2 Cluster: Remark: ORF contains 1 frameshift; n=3;
           Trichocomaceae|Rep: Remark: ORF contains 1 frameshift -
           Aspergillus niger
          Length = 296

 Score =  128 bits (309), Expect = 2e-28
 Identities = 78/219 (35%), Positives = 119/219 (54%), Gaps = 9/219 (4%)

Query: 77  DKILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRI-RTDVTKKVDWEV-EL 134
           + I C+GLNY+ H +E NL  P  P V++K  + +  PD+ + I R   +   DWE  EL
Sbjct: 65  NSIYCVGLNYRSHAKEANLNVPANPPVWTKPPAALASPDETIPISRFCASHLPDWEAGEL 124

Query: 135 CVVVGREASCVREEDALQHVAGYTVAQDISARDWQ-KEKNMGQFLLGKSMDTFCPLGPCV 193
             V  RE   V  E A Q++ GYTV  D+S R +Q  E++ GQF   K+ D F P+GP V
Sbjct: 125 VFVTSRECRDVTPEQASQYILGYTVGNDLSCRFFQLPEQSGGQFFYAKAFDKFAPIGP-V 183

Query: 194 LTSDEVGAAVELRVS--CSLNGVLKQSSSTAQ-LVHSIPSLLHRISSVMTLVPGDLILTG 250
           L S +V A      +    +NGV+KQ +   + ++ S   +L  +S   T+    +++TG
Sbjct: 184 LVSPDVFAKTRTSATLVTRINGVVKQDTVIGKDMIFSPERVLSWMSQSTTIPAYTVVMTG 243

Query: 251 TPGGVGMYRQPPEYLQPGDVLTSEIEKIGAFD--VRIEK 287
           TP G G+++ P + L+ GD +  EI  +G     VR E+
Sbjct: 244 TPAGAGVFQTPRQLLKDGDHIEVEISGLGTLKNVVRFEE 282


>UniRef50_O30145 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate
           isomerase; n=1; Archaeoglobus fulgidus|Rep:
           2-hydroxyhepta-2,4-diene-1,7-dioate isomerase -
           Archaeoglobus fulgidus
          Length = 324

 Score =  128 bits (308), Expect = 2e-28
 Identities = 81/232 (34%), Positives = 128/232 (55%), Gaps = 17/232 (7%)

Query: 60  ATIPLSSVTLTAPIHGVDKILCIGLNYKDHC----QEQNLTPPP----VPMVFSKFSSTI 111
           A  PLS V L AP+    K++     +++H     ++  ++ P     VP+ +     ++
Sbjct: 89  AVWPLSEVKLKAPLK--PKLMVDFSTFEEHVRMGFEKLGMSIPQEWYQVPVGYKMNPYSV 146

Query: 112 IGPDQPVRIRTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQ-- 169
           IGP++PV I    T+ +D+E+E  +VVG+    V +EDA+ +V GYT+  DISARD +  
Sbjct: 147 IGPEEPV-IWPSFTQILDYELEFGIVVGKRGKNVSKEDAMDYVLGYTIVNDISARDMEFI 205

Query: 170 --KEKNMGQFLLGKSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHS 227
             K   +G  L  K  D   P+GPC++T DE+     L++   +NG +   +ST  +   
Sbjct: 206 ELKAMPLGP-LKSKDFDNATPMGPCIVTKDEIKDPHNLKMVARVNGEVWSEASTKDMHWK 264

Query: 228 IPSLLHRISSVMTLVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIG 279
           IP L+  +S   T+ PG ++L+GTPGG G      + L+PGDV+  EIE IG
Sbjct: 265 IPDLIAHLSKDQTIHPGTVMLSGTPGG-GCGMHVGKLLKPGDVVELEIEGIG 315


>UniRef50_P73637 Cluster: 5-oxo-1,2,5-tricarboxilic-3-penten acid
           decarboxilase/isomer; n=10; Bacteria|Rep:
           5-oxo-1,2,5-tricarboxilic-3-penten acid
           decarboxilase/isomer - Synechocystis sp. (strain PCC
           6803)
          Length = 276

 Score =  127 bits (307), Expect = 3e-28
 Identities = 77/202 (38%), Positives = 115/202 (56%), Gaps = 12/202 (5%)

Query: 78  KILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRIRTDVTKKVDWEVELCVV 137
           KI+ +G NY+ H  E     P  P++F K  S I   DQ   +    +++VD+E EL V+
Sbjct: 59  KIVAVGRNYRAHAAELGNDVPAEPLLFFKPPSAIAA-DQEEIVYPSQSQRVDYEGELAVI 117

Query: 138 VGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLLGKSMDTFCPLGPCVLTSD 197
           +G++   + EE+A   + GYT+A DI+ARD Q++ +  Q+   K  D FCPLGP V+   
Sbjct: 118 IGKQVKDITEEEAASAIWGYTIANDITARDLQRQDS--QWTRAKGFDGFCPLGPWVVRHI 175

Query: 198 EVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPGDLILTGTPGGVGM 257
           +  A +E  V+       +Q+++ + +V + P L+  IS VMTL PGD+ILTGTP G+  
Sbjct: 176 DPEAHLETTVND--EETPRQATAISDMVFTPPVLVSYISRVMTLYPGDVILTGTPEGISA 233

Query: 258 YRQPPEYLQPGDVLTSEIEKIG 279
                  LQ GD +  EIE IG
Sbjct: 234 -------LQVGDKVEVEIEGIG 248


>UniRef50_Q9X4X5 Cluster: DitD; n=3; Proteobacteria|Rep: DitD -
           Pseudomonas abietaniphila
          Length = 293

 Score =  127 bits (307), Expect = 3e-28
 Identities = 77/227 (33%), Positives = 118/227 (51%), Gaps = 6/227 (2%)

Query: 62  IPLSSVTLTAPIHGVDKILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRIR 121
           I L+   +  P+    ++  +GLNY  H Q    T P  P+ + K  S ++G    ++  
Sbjct: 53  IALAQCRILPPLEPGARVFGVGLNYLSHLQHLGSTAPEHPLGYIKPESALVGASDDIQYP 112

Query: 122 TDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLLGK 181
             +T ++D+EVEL  V+ R      E  A   + GYT   DISARD  K       L  K
Sbjct: 113 A-LTAQLDYEVELVAVIARALG--DEPCASACLLGYTCGNDISARDAGKRIGRLDLLTQK 169

Query: 182 SMDTFCPLGPCVLTSDEVGAA-VELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMT 240
           +MD   P+GP V+T DE+G     L +  S+N   +Q  +T Q++  I  LL+ + + +T
Sbjct: 170 AMDRTTPVGPWVVTLDEIGVGQPHLDIELSVNDECRQFDNTRQMLFPIDELLNYVDARIT 229

Query: 241 LVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIGAFDVRIEK 287
           L PGDL+ TG+  GVG+  +   +LQPGD +   IE IG+   R+ +
Sbjct: 230 LQPGDLVFTGSTHGVGL--EDGRFLQPGDRVEVRIEGIGSMSNRVSQ 274


>UniRef50_Q3S4C0 Cluster: Putative hydratase; n=2;
           Proteobacteria|Rep: Putative hydratase - Polaromonas
           naphthalenivorans (strain CJ2)
          Length = 289

 Score =  127 bits (306), Expect = 4e-28
 Identities = 91/291 (31%), Positives = 147/291 (50%), Gaps = 35/291 (12%)

Query: 14  NIRVGYLEGDDIVDINKADSSLPT---------TLLQILRNGDLEKVKKLKSTKPATIPL 64
           N R+G ++G+ + D+  A   LP           L+ +L    LE ++++  + P T+PL
Sbjct: 8   NDRLGLVDGETVRDVTAALDVLPNHRYPLPIFDPLIALLPEV-LEAIRRIAPSSP-TLPL 65

Query: 65  SSVTLTAPIHGVDKILCIGLNYKDHCQE--------QNLTPPPVPMV--FSKFSSTIIGP 114
           +   L AP+    K++   +NYK H QE         N     +  +  F K +S+++GP
Sbjct: 66  AGRRLLAPVANPGKVIAAPVNYKKHLQEAREQVEIHHNNQVAEIEKIGLFLKATSSVVGP 125

Query: 115 DQPVRIRTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNM 174
              V I+    ++ D E EL  V+G+    +  E A  H++ YT+  D++ R  Q+    
Sbjct: 126 SHGVEIQHP-DRRNDHEAELVAVIGKTGRNIPRERAFDHISAYTIGLDMTVRGPQERS-- 182

Query: 175 GQFLLGKSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHR 234
               L KS+DT+  +GP ++T+DE+     L    ++NG  +Q ++T  LV  IP+L+  
Sbjct: 183 ----LRKSIDTYSVVGPWLVTADEIDDPQALDFWLTVNGERRQKANTRDLVLDIPALIEM 238

Query: 235 ISSVMTLVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIGAFDVRI 285
            SS  TL PGDL+ TGTP GVG        +  GD +T EI  IG  +V +
Sbjct: 239 ASSYYTLQPGDLLFTGTPEGVGP-------VVNGDEITVEIAGIGRMNVAV 282


>UniRef50_Q9F135 Cluster: Putative uncharacterized protein xlnF;
           n=1; Pseudomonas alcaligenes|Rep: Putative
           uncharacterized protein xlnF - Pseudomonas alcaligenes
          Length = 287

 Score =  126 bits (304), Expect = 7e-28
 Identities = 77/233 (33%), Positives = 126/233 (54%), Gaps = 23/233 (9%)

Query: 64  LSSVTLTAPIHGVDKILCIGLNYKDHCQEQNLTP-----PPVPMV-----FSKFSSTIIG 113
           L +VTL +P+    KI+   +NY DH  E N          + ++     F K  S+ +G
Sbjct: 68  LDAVTLISPVGNPGKIIAAPVNYADHLDESNQDKGINFGTEISLIDKYALFLKAGSSSVG 127

Query: 114 PDQPVRIRTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKN 173
           PD+ + +     ++ D EVEL +V+G+E   V  ++AL  VAGY +  DI+ R  +    
Sbjct: 128 PDEGISLPAVEGRRFDHEVELALVIGKETRRVTVDEALSSVAGYFIGLDITMRGTEDRSY 187

Query: 174 MGQFLLGKSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLH 233
                  KS D+F  +GP ++TSD  G+   +  S S+NG  +Q+++T  LV S+  ++ 
Sbjct: 188 R------KSFDSFTVMGPWLVTSDAFGSPEGVAFSLSVNGEQRQNANTNDLVWSVAKIIS 241

Query: 234 RISSVMTLVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIGAFDVRIE 286
             S   TL PGD+ILTGTP GVG        ++ GD +++ I++IG+ +V ++
Sbjct: 242 VASHAYTLYPGDVILTGTPAGVGP-------IKAGDKISASIDRIGSMEVPVK 287


>UniRef50_Q5KAM1 Cluster: Mitochondrion protein, putative; n=3;
           Eukaryota|Rep: Mitochondrion protein, putative -
           Cryptococcus neoformans (Filobasidiella neoformans)
          Length = 228

 Score =  126 bits (304), Expect = 7e-28
 Identities = 74/186 (39%), Positives = 105/186 (56%), Gaps = 6/186 (3%)

Query: 78  KILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQ-PVRIRTDVTKKVDWEVELCV 136
           KI+ IG NY DH +E     P  P  F K +S+ + PD  PV I   V   V  EVEL V
Sbjct: 10  KIVAIGRNYADHAKELGNAIPKEPFFFLKPTSSYLVPDNGPVEIPRGVI--VHHEVELGV 67

Query: 137 VVGREASCVREEDALQHVAGYTVAQDISARDWQ-KEKNMG-QFLLGKSMDTFCPLGPCVL 194
           V+G+    +    A  HVAGY++A D++AR+ Q K K  G  +   K  DTFCP+GP + 
Sbjct: 68  VIGKNGRDISPSAAFDHVAGYSLAVDMTARNVQDKAKAKGLPWSAAKGFDTFCPIGPFI- 126

Query: 195 TSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPGDLILTGTPGG 254
               +    ++ +  S+NG +KQS  T+ ++  IP L+  +S +M L  GDL+LTGTP G
Sbjct: 127 PKHFIADPTKVGLHFSVNGTVKQSGLTSDMIFDIPQLIAFVSGIMKLEEGDLVLTGTPSG 186

Query: 255 VGMYRQ 260
           VG  ++
Sbjct: 187 VGKIKR 192


>UniRef50_Q7VGX9 Cluster: Putative uncharacterized protein; n=1;
           Helicobacter hepaticus|Rep: Putative uncharacterized
           protein - Helicobacter hepaticus
          Length = 312

 Score =  126 bits (303), Expect = 9e-28
 Identities = 71/226 (31%), Positives = 127/226 (56%), Gaps = 12/226 (5%)

Query: 64  LSSVTLTAPIHGVDK-ILCIGLNYKDHCQEQNLTPPPV-------PMVFSKFSSTIIGPD 115
           L+ +TL API    + ++C+G+NY +H +E       +        + FSK  +     +
Sbjct: 82  LADITLLAPIPKPKQDVICLGINYLEHAKESAAYKNEIFDQKRENAVYFSKRVNYATPHN 141

Query: 116 QPVRIRTDVTKKVDWEVELCVVVGREASCVRE-EDALQHVAGYTVAQDISARDWQKEKNM 174
            P+ + +++T+K+D+EVEL VV+G      +  ++ +  + GYT+  DIS+RD Q++   
Sbjct: 142 APIPLHSNLTQKLDYEVELGVVLGSHLYKPKNMQEVIDSIFGYTIINDISSRDIQQKHK- 200

Query: 175 GQFLLGKSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHR 234
            Q+ +GKS++   P+GPC++++  + A   L +   +NG L+Q S T+ ++ +I + L+ 
Sbjct: 201 -QWYMGKSLEGSLPMGPCIVSARSIDAQ-NLAIKSYVNGELRQDSHTSLMICNITAALYE 258

Query: 235 ISSVMTLVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIGA 280
           +S    L    +I  GTP GVGM   PP +L   D +  EI+ IG+
Sbjct: 259 LSHYCMLQAASIISMGTPSGVGMGFNPPRFLSNNDEIVCEIQHIGS 304


>UniRef50_Q979A6 Cluster: 2-hydroxyhepta-2,4-diend-1,7-dioate
           isomerase; n=1; Thermoplasma volcanium|Rep:
           2-hydroxyhepta-2,4-diend-1,7-dioate isomerase -
           Thermoplasma volcanium
          Length = 268

 Score =  124 bits (300), Expect = 2e-27
 Identities = 69/211 (32%), Positives = 115/211 (54%), Gaps = 7/211 (3%)

Query: 72  PIHGVDKILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRIRTDVTKKVDWE 131
           P     KI    +N++ H  E +   PP P  F+KFS+ ++  +  +R    + KK+D+E
Sbjct: 55  PAVNPQKIFLPAVNFRSHSAESDTRFPPKPYFFTKFSNALVANNSELRTPGTI-KKLDYE 113

Query: 132 VELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQ--KEKNMG-QFLLGKSMDTFCP 188
            E   V+G++   +  EDA   + G+T+A D+SARD+Q  +    G  ++ GK+ D   P
Sbjct: 114 GETGAVIGKKCYNIPAEDAYDCIFGFTIANDLSARDFQFPEMHPYGYNWVQGKAFDGALP 173

Query: 189 LGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPGDLIL 248
           +GP + T DE+   +E+     +NG  +Q  +T  +V S   L+  +S  +TL PGD+I 
Sbjct: 174 VGPYITTKDEIQFPLEIETK--VNGETRQKGTTDDMVFSFQDLISTLSQNITLEPGDIIT 231

Query: 249 TGTPGGVGMYRQPPEYLQPGDVLTSEIEKIG 279
           +GTP GV  + +   YL+ GDV+   +  +G
Sbjct: 232 SGTPAGVAAFSE-KLYLKSGDVIEISVSSLG 261


>UniRef50_P34673 Cluster: Uncharacterized protein ZK688.3; n=5;
           Eukaryota|Rep: Uncharacterized protein ZK688.3 -
           Caenorhabditis elegans
          Length = 214

 Score =  124 bits (300), Expect = 2e-27
 Identities = 69/180 (38%), Positives = 105/180 (58%), Gaps = 4/180 (2%)

Query: 78  KILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRIRTDVTKKVDWEVELCVV 137
           KI+C+G NYKDH  E     P  PM+F K  ++ I   +P+ +     + +  EVEL VV
Sbjct: 13  KIVCVGRNYKDHALELGNAIPKKPMLFVKTVNSFIVEGEPI-VAPPGCQNLHQEVELGVV 71

Query: 138 VGREASCVREEDALQHVAGYTVAQDISARDWQKE-KNMG-QFLLGKSMDTFCPLGPCVLT 195
           + ++AS + + DA+ ++ GYTVA D++ARD+Q E K  G  + L KS D  CP+G  +  
Sbjct: 72  ISKKASRISKSDAMDYIGGYTVALDMTARDFQDEAKKAGAPWFLAKSFDGSCPIGGFLPV 131

Query: 196 SDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPGDLILTGTPGGV 255
           SD +    ++ + C +NG  +Q   T  ++  IP+LL   +   TL  GD++LTGTP GV
Sbjct: 132 SD-IPNPHDVELFCKINGKDQQRCRTDVMIFDIPTLLEYTTQFFTLEVGDVVLTGTPAGV 190


>UniRef50_Q66BX8 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate
           isomerase / 5-carboxymeth..; n=42; Bacteria|Rep:
           2-hydroxyhepta-2,4-diene-1,7-dioate isomerase /
           5-carboxymeth.. - Yersinia pseudotuberculosis
          Length = 254

 Score =  124 bits (299), Expect = 3e-27
 Identities = 73/207 (35%), Positives = 110/207 (53%), Gaps = 9/207 (4%)

Query: 79  ILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRIRTDVTKKVDWEVELCVVV 138
           +  +GLNY DH  E + +PP  P++F K   +  G  Q V +R D  + + +E EL VVV
Sbjct: 46  LFALGLNYVDHAAELDFSPPKEPLIFIKAPHSFTGHRQ-VSVRPDNIEYMHYEAELVVVV 104

Query: 139 GREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLLGKSMDTFCPLGPCVLTSDE 198
           G+ A  +    A+ +VAGYT+  D + RD+  E      L  KS DT  P+GP ++   +
Sbjct: 105 GKPARYLNPAHAMDYVAGYTLCNDYAVRDYL-ENYYRPNLRVKSRDTLTPIGPWIVDKAD 163

Query: 199 VGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPGDLILTGTPGGVGMY 258
           +     L +   +NG L Q  +TA L+  IP L+  +S  +TL PGD+I TGTP G+   
Sbjct: 164 IPNPHNLVIRTWVNGELCQRGNTADLIFDIPFLMAYLSEFITLQPGDMIATGTPKGL--- 220

Query: 259 RQPPEYLQPGDVLTSEIEKIGAFDVRI 285
                 + PGD +  E++ IG    R+
Sbjct: 221 ----SNVVPGDEVVVEVDGIGCLLNRV 243


>UniRef50_A2U6Z6 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=1;
           Bacillus coagulans 36D1|Rep: Fumarylacetoacetate (FAA)
           hydrolase - Bacillus coagulans 36D1
          Length = 278

 Score =  123 bits (297), Expect = 5e-27
 Identities = 92/280 (32%), Positives = 138/280 (49%), Gaps = 25/280 (8%)

Query: 17  VGYLEGDDIVDINKA---DSSLP-TTLLQILRNGDLEKVK-KLKSTKPATIPLSSVTLTA 71
           +G + GD I DI+K    D + P  + L+++ + D  K   + +     + PL+ VTL  
Sbjct: 11  LGAVTGDRITDISKVTNWDRNDPHASFLKLMAHYDEWKENIEQEIASGVSYPLNGVTLKC 70

Query: 72  PIHGVDKILCIGLNYKDHCQEQNLTPPPVPM------VFSKFSSTIIGPDQPVRIRTDVT 125
           P+ G  KI    +NY  H +E N      P       +F K   ++ GP  P+ I     
Sbjct: 71  PVPGAGKIWAAPVNYLKHQEEMNHQFNNAPRTIEELSLFLKSPQSLSGPTDPI-ILPFPE 129

Query: 126 KKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLLGKSMDT 185
           ++ D E EL  +VG++A  V+  +A  ++ GY    DIS R   +E+        KS DT
Sbjct: 130 RRTDHEAELGYIVGKKAKNVKAREAKDYIFGYFALLDISIRG-NEERTWR-----KSFDT 183

Query: 186 FCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPGD 245
           F P+GP ++T DE+    +L +S  +N  L+QS ST  L++            MTL PGD
Sbjct: 184 FTPIGPWIVTEDEIKNPNDLAISLWVNDELRQSGSTKYLIYDCYKCFELACDHMTLHPGD 243

Query: 246 LILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIGAFDVRI 285
           +I TGTP GVG  R+       GD +   IE+IG F V +
Sbjct: 244 IIATGTPEGVGPIRE-------GDRVKISIEQIGEFTVDV 276


>UniRef50_Q01NL2 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=1;
           Solibacter usitatus Ellin6076|Rep: Fumarylacetoacetate
           (FAA) hydrolase - Solibacter usitatus (strain Ellin6076)
          Length = 252

 Score =  122 bits (295), Expect = 8e-27
 Identities = 81/221 (36%), Positives = 111/221 (50%), Gaps = 15/221 (6%)

Query: 60  ATIPLSSVTLTAPIHGVDKILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVR 119
           AT+ LS V L  P     KIL +GLNYK H   +    P  P +F K  S +  P  P+ 
Sbjct: 39  ATLKLSDVKLLYPCEA-GKILAVGLNYKSHLGSR--PQPAHPEMFYKPISALQNPGDPIE 95

Query: 120 IRTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQK-EKNMGQFL 178
           +  D T  V  E E+ VVVG        ++A   V G T   D+S R WQ  EK   Q+ 
Sbjct: 96  LPRDATD-VHSEGEMVVVVGGYLRNASVDEAADAVFGVTCGNDVSDRSWQHGEKKDLQWW 154

Query: 179 LGKSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSV 238
             K  DTF PLGP +++  + G   +L +   +NG   Q   T+ L+  IP++L  IS  
Sbjct: 155 RAKGSDTFAPLGPAIVSGVDYG---KLLLQTRINGETVQKQFTSDLIFDIPTVLSWISGW 211

Query: 239 MTLVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIG 279
           +TL PGDL+ TGTPG           + PGD++  E+E +G
Sbjct: 212 VTLFPGDLVYTGTPGNT-------RKMSPGDLVEVELEGVG 245


>UniRef50_A5V6X8 Cluster: 5-carboxymethyl-2-hydroxymuconate
           Delta-isomerase; n=1; Sphingomonas wittichii RW1|Rep:
           5-carboxymethyl-2-hydroxymuconate Delta-isomerase -
           Sphingomonas wittichii RW1
          Length = 325

 Score =  122 bits (293), Expect = 1e-26
 Identities = 73/220 (33%), Positives = 112/220 (50%), Gaps = 18/220 (8%)

Query: 76  VDKILCIGLNYKDHCQEQNLT-PPPVPMVFSKFSSTIIGP------DQPVRIRTDVT--- 125
           V K+L    NY DH +    T  P +P+         + P      + P     D+    
Sbjct: 92  VGKMLFAAANYSDHVRNMRKTFTPDIPLADQGKQLPPLRPYMFGKINVPTGAFDDIILPP 151

Query: 126 --KKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARD--WQKEKNM--GQFLL 179
             +++DWE EL VV+G     +R  +A +H+AGY    D+S RD  W++++      +L 
Sbjct: 152 GMERIDWEAELMVVIGTPGLAIRPAEAHRHIAGYMTGNDVSCRDRTWREDRPTIRSDWLG 211

Query: 180 GKSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVM 239
           GKS D+F PLGP +     V    +L +   +NG LKQ  ++  +   I   +   SS+M
Sbjct: 212 GKSYDSFAPLGPLLTPRQFVPDHADLAIRLWVNGELKQDGNSRDMTFGIEEQIEYASSMM 271

Query: 240 TLVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIG 279
           TL+PGD+I TGTP G G  R   E+L+ GD++ +E+E  G
Sbjct: 272 TLLPGDVIATGTPAGTGQER--GEFLKEGDIVETEVESCG 309


>UniRef50_A5V8P5 Cluster: 5-carboxymethyl-2-hydroxymuconate
           Delta-isomerase; n=1; Sphingomonas wittichii RW1|Rep:
           5-carboxymethyl-2-hydroxymuconate Delta-isomerase -
           Sphingomonas wittichii RW1
          Length = 343

 Score =  121 bits (291), Expect = 2e-26
 Identities = 70/183 (38%), Positives = 103/183 (56%), Gaps = 7/183 (3%)

Query: 101 PMVFSKFSSTIIGPDQPVRIRTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVA 160
           P  F K  S+I+GP   + +  D ++++DWE+EL VV+G+ A  V  + AL HVAGY V 
Sbjct: 137 PFAFLKPFSSILGPFDDLAVPAD-SEQLDWELELGVVIGKPARRVGRDRALDHVAGYVVV 195

Query: 161 QDISARDWQKEKNMGQFLL----GKSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLK 216
            DIS RD     ++ Q  L    GKS     P+GP ++ +  V    +L ++  LNG + 
Sbjct: 196 NDISVRDHLYRPDVPQLGLDWVSGKSGPGMLPMGPLIVPAAFVADPQQLMITLKLNGEVM 255

Query: 217 QSSSTAQLVHSIPSLLHRISSVMTLVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIE 276
           Q  STA ++  I  L+   S  M L+PGD+I TG+P G G +     +L+PGDV+   IE
Sbjct: 256 QHESTADMIFPIARLIEAFSVHMQLLPGDIICTGSPSGNGTHF--GRFLRPGDVMEGTIE 313

Query: 277 KIG 279
            +G
Sbjct: 314 GLG 316


>UniRef50_A7BDZ2 Cluster: Putative uncharacterized protein; n=1;
           Actinomyces odontolyticus ATCC 17982|Rep: Putative
           uncharacterized protein - Actinomyces odontolyticus ATCC
           17982
          Length = 255

 Score =  120 bits (288), Expect = 6e-26
 Identities = 80/217 (36%), Positives = 114/217 (52%), Gaps = 14/217 (6%)

Query: 64  LSSVTLTAPIHGVDKILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRIRTD 123
           L  V L +P+    K++ IG NY D     +  P P   +F K +++++GPD P+ I   
Sbjct: 45  LDEVRLLSPVIPRSKVVGIGDNYSDTPIPADERPEPP--IFLKANTSVVGPDDPIAIPA- 101

Query: 124 VTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLLGKSM 183
            +  V +E EL +V+   A  V  EDA Q + GYT+A D +ARD       G +  GKS 
Sbjct: 102 WSNAVAFEGELAIVIKSLAKDVSVEDAPQMILGYTIANDATARD---AMTGGPWSRGKSF 158

Query: 184 DTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVP 243
           D+ CPLGP + T D       L +   LNG + Q SSTA ++ +   L+  +S  MTL+P
Sbjct: 159 DSACPLGPWI-TVDPALDVTNLAIRSYLNGEIAQDSSTAHMIWNPFELVSYLSHQMTLLP 217

Query: 244 GDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIGA 280
           GD+I TG P G        E +  GD +  EIE IG+
Sbjct: 218 GDVIATGAPAGA-------EIVHAGDRVEIEIEGIGS 247


>UniRef50_Q1DXV6 Cluster: Putative uncharacterized protein; n=2;
           Eurotiomycetidae|Rep: Putative uncharacterized protein -
           Coccidioides immitis
          Length = 327

 Score =  120 bits (288), Expect = 6e-26
 Identities = 68/232 (29%), Positives = 118/232 (50%), Gaps = 6/232 (2%)

Query: 51  VKKLKSTKPAT-IPLSSVTLTAPIHGVDKILCIGLNYKDHCQEQNLTPPPVPMVFSKFSS 109
           ++ L+S   +T + +  +    P+ G++ I+C+GLNY++H  E +L  P  P ++ K   
Sbjct: 91  IEALESDGQSTNVTVEKLLAPVPVTGIN-IICVGLNYRNHANEASLPIPTCPPMWYKAPP 149

Query: 110 TIIGPDQPVRIRTDVTKKV-DWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDW 168
            +  PD  + +     K   D+E EL +V+      +   +A  H+ GYT+  D++AR +
Sbjct: 150 ALADPDSEIPVPPQAQKSFPDFEGELTIVLRNTIKSISASEATSHILGYTIGNDLTARFF 209

Query: 169 QKEKNMGQFLLGKSMDTFCPLGPCVLTSDEVGAA-VELRVSCSLNGVLKQSSSTAQLVHS 227
           Q+    GQ+   K  D F PLGP ++       +    R++  +NG + Q S     +  
Sbjct: 210 QRACG-GQYTHAKGFDNFAPLGPRLVHPSVFSPSDASRRITTRVNGRVVQDSPF-DFIFP 267

Query: 228 IPSLLHRISSVMTLVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIG 279
           +  L+  +S   T+  G  I+TGTP GVG ++ P   LQ GD +  E++ IG
Sbjct: 268 VDELVSFLSEGTTIPAGTAIMTGTPAGVGWFQDPKCPLQHGDAVEVEVQPIG 319


>UniRef50_A0IRN0 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=4;
           Proteobacteria|Rep: Fumarylacetoacetate (FAA) hydrolase
           - Serratia proteamaculans 568
          Length = 287

 Score =  119 bits (286), Expect = 1e-25
 Identities = 79/233 (33%), Positives = 122/233 (52%), Gaps = 24/233 (10%)

Query: 63  PLSSVTLTAPIHGVDKILCIGLNYKDHCQEQNL----------TPPPVPMVFSKFSSTII 112
           PL  V+L AP+    KI+   +NY+DH  E N           T      +F K +S++ 
Sbjct: 64  PLEQVSLNAPVANPGKIVAAPINYRDHIAEANADQQINHGKVYTDISEYGLFLKANSSLC 123

Query: 113 GPDQPVRIRTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEK 172
           GP++ + +     ++ D EVEL V++G+ A  +  + AL+ V GY +  D++ R  +   
Sbjct: 124 GPNEIIPLPIP-GRRTDPEVELAVIIGQRARNLPVDQALEAVFGYAIGIDMTVRGSEFPS 182

Query: 173 NMGQFLLGKSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLL 232
                   KS D F  LGP ++T DE+G    L +S  +NG L+Q S+T  L++++  L+
Sbjct: 183 ------FRKSADGFSVLGPWIVTPDEIGDPNTLDLSIRVNGQLRQHSNTRHLIYNVQRLI 236

Query: 233 HRISSVMTLVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIGAFDVRI 285
              S++ TL PGD+I TGTP GV         +Q GD +   IE+IGA  V I
Sbjct: 237 AYASAMFTLWPGDVIYTGTPSGVSA-------IQAGDRIEVSIERIGAMSVTI 282


>UniRef50_A5V6J4 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=1;
           Sphingomonas wittichii RW1|Rep: Fumarylacetoacetate
           (FAA) hydrolase - Sphingomonas wittichii RW1
          Length = 329

 Score =  118 bits (285), Expect = 1e-25
 Identities = 67/190 (35%), Positives = 105/190 (55%), Gaps = 7/190 (3%)

Query: 101 PMVFSKFSSTIIGPDQPVRIRTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVA 160
           P VF+K  +T+ G +  + +  + TK  DWE+EL VV+GR    +  E A++HVAGY + 
Sbjct: 139 PYVFTKPITTVAGANDTLILPANTTKP-DWELELAVVIGRGGIRIPREAAMEHVAGYAIV 197

Query: 161 QDISARDW---QKEKNMG-QFLLGKSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLK 216
            D+SARD       K +G  +L  K  + F P GP ++ +  +     LR+  S+ G + 
Sbjct: 198 NDVSARDLIPRTDYKLLGTDWLRSKGQEGFLPFGPYMVPARFIADPYALRIRLSVEGQMM 257

Query: 217 QSSSTAQLVHSIPSLLHRISSVMTLVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIE 276
           Q  +TA ++  I   +  IS    L+PGD+I TG+P G G +     +LQ GD++  EI+
Sbjct: 258 QDETTADMMFDIARQIEYISRYSRLLPGDVICTGSPAGNGTHYN--RFLQDGDLMIGEID 315

Query: 277 KIGAFDVRIE 286
            +GA  +R E
Sbjct: 316 GLGAQRIRCE 325


>UniRef50_Q8G4X7 Cluster: Possible
           2-hydroxyhepta-2,4-diene-1,7-dioate isomerase in the
           fumarylacetoacetate hydrolase family; n=6;
           Bifidobacterium|Rep: Possible
           2-hydroxyhepta-2,4-diene-1,7-dioate isomerase in the
           fumarylacetoacetate hydrolase family - Bifidobacterium
           longum
          Length = 292

 Score =  118 bits (284), Expect = 2e-25
 Identities = 76/221 (34%), Positives = 118/221 (53%), Gaps = 14/221 (6%)

Query: 62  IPLSSVTLTAPIHGVDKILCIGLNYKDHCQEQNLTPPPVPMV-FSKFSSTIIGPDQPVRI 120
           I L S  + + ++G+ K       +        +   P  MV F+K S+++IGPD P+ +
Sbjct: 74  IRLLSPVIPSKVYGLAKNYEAHAQFMHEAGHSEIAHAPEDMVIFTKPSTSVIGPDDPI-V 132

Query: 121 RTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLLG 180
               +K +++E E+ VV+GR A  V  E+A+ +V G+T   D++ RD Q       +   
Sbjct: 133 YPACSKDMNFEPEVAVVMGRIAKNVTVENAMDYVLGFTCVNDVTLRDLQGIDPT--WTRA 190

Query: 181 KSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNG--VLKQSSSTAQLVHSIPSLLHRISSV 238
           K  DT CPLGP ++  D++    + ++S +LNG  V   S +TA L+H IP  +  ISS 
Sbjct: 191 KGFDTSCPLGPWIVMRDDLDWK-DAKISFTLNGEDVPMASGTTANLIHGIPEQIAAISSF 249

Query: 239 MTLVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIG 279
            TL+PGD+I+TGTP   G       +L PGD     +E IG
Sbjct: 250 STLLPGDVIMTGTPNASG-------HLDPGDETIVHVEGIG 283


>UniRef50_Q9LBE3 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate
           isomerase/5-carboxymethyl-2-oxo- hex-3-ene-1,7-dioate
           decarboxylase-related protein; n=4; Deinococci|Rep:
           2-hydroxyhepta-2,4-diene-1,7-dioate
           isomerase/5-carboxymethyl-2-oxo- hex-3-ene-1,7-dioate
           decarboxylase-related protein - Deinococcus radiodurans
          Length = 250

 Score =  118 bits (283), Expect = 2e-25
 Identities = 79/228 (34%), Positives = 122/228 (53%), Gaps = 17/228 (7%)

Query: 61  TIPLSSVTLTAPIHGVDKILCIGLNYKDHCQEQ-NLTP--PPVPMVFSKFSSTIIGPDQP 117
           T+ LS   L AP     KI+C+G NY DH +E  N T   P  P +F K  + +  P   
Sbjct: 36  TLALSEARLLAPAEP-SKIVCVGRNYLDHIRELGNDTGDLPAEPGIFLKGPNALAEPGGT 94

Query: 118 VRIRTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQF 177
           V   +  ++   +E EL +V+G+ A  ++ ++AL  V GYT   D++ARD QK     Q+
Sbjct: 95  VEYPS-WSENFHFEGELALVIGQRARNLKADEALGAVLGYTCGLDLTARDRQKTDL--QW 151

Query: 178 LLGKSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISS 237
              K+ D FCPLGP ++T  +     ++RV   +NG  +Q   T+ ++  +  +L  ++ 
Sbjct: 152 FRAKAADRFCPLGPWLVTQFDPS---DVRVQTRVNGEPRQDGRTSHMIFDVVQILTYLTR 208

Query: 238 VMTLVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIGAFDVRI 285
            +TL PGD++LTGTP GVG        LQ GD +  E++ IG  +  I
Sbjct: 209 FVTLEPGDVVLTGTPEGVGP-------LQRGDRVEVEVDGIGVLETFI 249


>UniRef50_P76004 Cluster: Uncharacterized protein ycgM; n=41;
           Gammaproteobacteria|Rep: Uncharacterized protein ycgM -
           Escherichia coli (strain K12)
          Length = 219

 Score =  118 bits (283), Expect = 2e-25
 Identities = 73/199 (36%), Positives = 104/199 (52%), Gaps = 10/199 (5%)

Query: 76  VDKILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRIRTDVTKKVDWEVELC 135
           V K++C+G NY  H +E     P  P++F K  + +    QP+ I +D    V  EVEL 
Sbjct: 16  VSKVVCVGSNYAKHIKEMGSAVPEEPVLFIKPETALCDLRQPLAIPSDFGS-VHHEVELA 74

Query: 136 VVVGREASCVREEDALQHVAGYTVAQDISARDWQ-KEKNMGQ-FLLGKSMDTFCPLGPCV 193
           V++G       EE   + +AGY VA D++ RD Q K K  GQ +   K+ D  CPL   +
Sbjct: 75  VLIGATLRQATEEHVRKAIAGYGVALDLTLRDVQGKMKKAGQPWEKAKAFDNSCPLSGFI 134

Query: 194 LTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPGDLILTGTPG 253
             ++  G      +S S+NG  +Q  +TA ++H I  L+  +S   TL  GD++LTGTP 
Sbjct: 135 PAAEFTGDPQNTTLSLSVNGEQRQQGTTADMIHKIVPLIAYMSKFFTLKAGDVVLTGTPD 194

Query: 254 GVGMYRQPPEYLQPGDVLT 272
           GVG        LQ GD LT
Sbjct: 195 GVGP-------LQSGDELT 206


>UniRef50_Q8NQY2 Cluster: 2-keto-4-pentenoate
           hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase;
           n=5; Corynebacterium|Rep: 2-keto-4-pentenoate
           hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase -
           Corynebacterium glutamicum (Brevibacterium flavum)
          Length = 268

 Score =  116 bits (280), Expect = 5e-25
 Identities = 77/223 (34%), Positives = 119/223 (53%), Gaps = 17/223 (7%)

Query: 63  PLSSVTLTAPIHGVDKILCIGLNYKDHCQE--QNLTPPPVPMVFSKFSSTIIGPDQPVRI 120
           PL  V L AP+    K++ IG NY DH  E  +       P +F K  + + GP+ P+RI
Sbjct: 48  PLKDVRLLAPMLP-SKVVAIGRNYADHVAEVFKKSAESLPPTLFLKPPTAVTGPESPIRI 106

Query: 121 RTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLLG 180
            +  TK V++E EL VV+G+    V+ +D    V G+T+  D+S+RD Q     GQ+   
Sbjct: 107 PSFATK-VEFEGELAVVIGKPCKNVKADDWKSVVLGFTIINDVSSRDLQFAD--GQWARA 163

Query: 181 KSMDTFCPLGPCVLTS----DEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRIS 236
           K +DTF P+GP + T     D     ++ R++      LKQ S++ Q++  +  ++  I+
Sbjct: 164 KGIDTFGPIGPWIETDINSIDLDNLPIKARLTHDGETQLKQDSNSNQMIMKMGEIIEFIT 223

Query: 237 SVMTLVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIG 279
           + MTL+PGD+I TG+P G        E +  GD +  EI  IG
Sbjct: 224 ASMTLLPGDVIATGSPAGT-------EAMVDGDYIEIEIPGIG 259


>UniRef50_Q5LT14 Cluster: Fumarylacetoacetate hydrolase family
           protein; n=1; Silicibacter pomeroyi|Rep:
           Fumarylacetoacetate hydrolase family protein -
           Silicibacter pomeroyi
          Length = 281

 Score =  116 bits (279), Expect = 7e-25
 Identities = 70/223 (31%), Positives = 108/223 (48%), Gaps = 7/223 (3%)

Query: 60  ATIPLSSVTLTAPIHGVDKILCIGLNYKDHCQEQNLTPP-PVPMV-FSKFSSTIIGPDQP 117
           A +PL S+    PI    KILC G+NY+       + PP P  +V FS+   T++G    
Sbjct: 54  AALPLDSLVWLPPIPAPGKILCAGMNYRKPYPVAGVAPPDPGHVVLFSRHPQTLVGHGAM 113

Query: 118 VRI-RTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQ 176
           + + +    +  D+E E+  V+G+    +  E AL HV GY+   + S R W K      
Sbjct: 114 LEMPQGAAAESFDFEGEIVAVIGQPGRHIAPEAALGHVLGYSAMNEGSVRGWMKHSVHA- 172

Query: 177 FLLGKSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRIS 236
              GK+       GP + T+DE G    + +   +NG   QS S A ++  +  L+  IS
Sbjct: 173 ---GKNFHASGSWGPWITTADEAGDIAGMTLETRVNGTPMQSDSGAGMIFGLAELIAYIS 229

Query: 237 SVMTLVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIG 279
            +  L  GD+I TG+P G G  R PP +L+ GD +   +  +G
Sbjct: 230 HIQPLEAGDIIATGSPDGTGGSRTPPAFLRSGDRVAVTVGGVG 272


>UniRef50_A0HJM1 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=2;
           Proteobacteria|Rep: Fumarylacetoacetate (FAA) hydrolase
           - Comamonas testosteroni KF-1
          Length = 289

 Score =  116 bits (279), Expect = 7e-25
 Identities = 73/220 (33%), Positives = 113/220 (51%), Gaps = 18/220 (8%)

Query: 72  PIHGVDKILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTII----GPDQPVRIRTDVTKK 127
           PIH   +I C+G NY+DH +E   T    P  F K +   +    G    V   T +T+ 
Sbjct: 81  PIH---RIYCVGRNYEDHAKEMGFTGREPPFFFMKPADATVALEAGSTGQVAYPT-LTQN 136

Query: 128 VDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKE-KNMGQ-FLLGKSMDT 185
           +  E+EL V +G+    ++  DALQ++ GY V  D++ RD Q E K  G+ + +GK+ + 
Sbjct: 137 LHHEIELVVAIGKAGKNIKAADALQYIYGYAVGLDMTRRDLQNEMKKQGRPWCIGKAFEQ 196

Query: 186 FCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPGD 245
             P+GP +  +D+ G      +S  +NG  +Q S   +L+ +I   +  +SS   L PGD
Sbjct: 197 SAPIGP-ITPADQAGDIANAEISLQVNGDYRQRSHIHKLIWNIAETIEHLSSAWELQPGD 255

Query: 246 LILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIGAFDVRI 285
           LI+TGTP GV         +  GDVL   I  + A  ++I
Sbjct: 256 LIMTGTPEGVAA-------VVKGDVLEGAITGLEAIRIQI 288


>UniRef50_A4WBF8 Cluster: 5-carboxymethyl-2-hydroxymuconate
           Delta-isomerase; n=2; Gammaproteobacteria|Rep:
           5-carboxymethyl-2-hydroxymuconate Delta-isomerase -
           Enterobacter sp. 638
          Length = 219

 Score =  116 bits (278), Expect = 9e-25
 Identities = 66/183 (36%), Positives = 97/183 (53%), Gaps = 3/183 (1%)

Query: 76  VDKILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRIRTDVTKKVDWEVELC 135
           V K++C+G NY  H QE     P  P++F K  + +    QP+ +   +   V  EVEL 
Sbjct: 16  VSKVVCVGSNYAKHIQEMGSAVPDEPVLFIKPETALCDIRQPLALPQGLGS-VHHEVELA 74

Query: 136 VVVGREASCVREEDALQHVAGYTVAQDISARDWQ-KEKNMGQ-FLLGKSMDTFCPLGPCV 193
           V++G       EE   + +AGY +A D++ RD Q K K  GQ +   K  D  CP+   +
Sbjct: 75  VLIGATLRQASEEHVQKAIAGYGIALDLTLRDVQGKMKKAGQPWEKAKGFDNSCPISGFI 134

Query: 194 LTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPGDLILTGTPG 253
            T+D         +S  +NG ++Q  +TA ++H I  L+  +S   TL PGD+ILTGTP 
Sbjct: 135 PTADFKADPQNTSLSLKVNGDIRQQGNTADMIHKILPLIAYMSRYFTLKPGDVILTGTPE 194

Query: 254 GVG 256
           GVG
Sbjct: 195 GVG 197


>UniRef50_Q70P92 Cluster: MelH protein; n=3; Cystobacteraceae|Rep:
           MelH protein - Melittangium lichenicola
          Length = 329

 Score =  115 bits (276), Expect = 2e-24
 Identities = 73/233 (31%), Positives = 119/233 (51%), Gaps = 10/233 (4%)

Query: 38  TLLQILRNGDLEKVKKLKSTKPATIPLSSVTLTAPIHGVDKILCIGLNYKDHCQEQNLTP 97
           TL   L  G     +   + +  T+ +  V L +P+     ++C G NY+ H  E    P
Sbjct: 33  TLAGFLGEGAAHARRLAAAPEGETLAVRDVELLSPVTAPCNVVCQGQNYRSHMLEVGQDP 92

Query: 98  PP--VPMVFSKFSSTIIGPDQPVRIRTDVTKKVDWEVELCVVVGREAS--CVREEDAL-Q 152
                   F K SS++      + ++ +  + +D+E+EL +V+GR  S  C  E + L +
Sbjct: 93  EAKNFNQFFRKASSSLTSGHGDI-VKPERVRMLDYEIELGLVIGRPLSGPCRVERERLHE 151

Query: 153 HVAGYTVAQDISARDWQKEKNMGQFLLGKSMDTFCPLGPCV--LTSDEVGAAVELRVSCS 210
            VAG  +  D+SARD Q  +  GQ+   KS  TFCP GP +  L +++    + L++  S
Sbjct: 152 FVAGLVICNDVSARDIQLAE--GQWYKSKSFRTFCPAGPYLYLLDAEDNARVMNLKLHLS 209

Query: 211 LNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPGDLILTGTPGGVGMYRQPPE 263
           +N   +Q S+T+++V+     L  +S VM L PGDL++TGTP GV      P+
Sbjct: 210 VNDQTRQDSNTSEMVYPPEETLSELSEVMDLFPGDLVMTGTPRGVAAGHNAPK 262


>UniRef50_Q6P587 Cluster: Fumarylacetoacetate hydrolase
           domain-containing protein 1; n=21; Eumetazoa|Rep:
           Fumarylacetoacetate hydrolase domain-containing protein
           1 - Homo sapiens (Human)
          Length = 224

 Score =  113 bits (273), Expect = 4e-24
 Identities = 65/187 (34%), Positives = 103/187 (55%), Gaps = 4/187 (2%)

Query: 79  ILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRIRTDVTKKVDWEVELCVVV 138
           I+C+G NY DH +E        P++F K  ST   P+    +    T+ +  E+EL VV+
Sbjct: 20  IVCVGRNYADHVREMRSAVLSEPVLFLK-PSTAYAPEGSPILMPAYTRNLHHELELGVVM 78

Query: 139 GREASCVREEDALQHVAGYTVAQDISARDWQKE-KNMG-QFLLGKSMDTFCPLGPCVLTS 196
           G+    V E  A+ +V GY +  D++ARD Q E K  G  + L KS    CP+   V   
Sbjct: 79  GKRCRAVPEAAAMDYVGGYALCLDMTARDVQDECKKKGLPWTLAKSFTASCPVSAFV-PK 137

Query: 197 DEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPGDLILTGTPGGVG 256
           +++    +L++   +NG L+Q   T+ ++ SIP ++  +S ++TL  GD+ILTGTP GVG
Sbjct: 138 EKIPDPHKLKLWLKVNGELRQEGETSSMIFSIPYIISYVSKIITLEEGDIILTGTPKGVG 197

Query: 257 MYRQPPE 263
             ++  E
Sbjct: 198 PVKENDE 204


>UniRef50_Q81VG5 Cluster: Fumarylacetoacetate hydrolase family
           protein; n=13; Bacillus|Rep: Fumarylacetoacetate
           hydrolase family protein - Bacillus anthracis
          Length = 318

 Score =  113 bits (272), Expect = 5e-24
 Identities = 86/303 (28%), Positives = 143/303 (47%), Gaps = 19/303 (6%)

Query: 1   MKLVQFSYKDSPKNIRVGYLEGDDIVDINKA-DSSLPTTLLQILRNGD--LEKVKKLKST 57
           MK V F      K +R G+LEGD ++D+N A D  LP+++   L   D  +E ++ +K+ 
Sbjct: 1   MKFVTFRLPS--KEMRAGWLEGDKVIDMNLASDGKLPSSMFAFLEKADEYVEVLRNIKNP 58

Query: 58  KPATIPLSSVTLTAPIHGVDKI---LCIGLNYKDHCQEQNLTPPP----VPMVFSKFSST 110
           +     L  V L A I     I        + K     + L   P    +P+ +      
Sbjct: 59  EKGIYSLEEVQLAAAIPNPSSIRDFYAFEQHVKTARGRRGLDVVPEWYDIPVFYFTNHRA 118

Query: 111 IIGPDQPVRIRTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQK 170
           +IGP+  V I    ++K+D+E+E+  V+G+E   +  E A +++ GY +  D SARD Q 
Sbjct: 119 VIGPNDVV-IGPKKSEKIDYELEIACVIGKEGRNISREQAEEYIFGYCIMNDWSARDLQA 177

Query: 171 EKNMGQFLLGKSMDTFCPLGPCVLTSDEV-----GAAVELRVSCSLNGVLKQSSSTAQLV 225
            +        K  D    LG  ++T +E+     G   EL ++  +NG L    +   + 
Sbjct: 178 TEMKVGLGPAKGKDFATSLGAHLVTKEELDVYRNGDRYELEMTAHVNGKLLSKGNFQDIY 237

Query: 226 HSIPSLLHRISSVMTLVPGDLILTGTPG-GVGMYRQPPEYLQPGDVLTSEIEKIGAFDVR 284
           ++   ++ R S  +TL PGD+I +GT G G  +     E+LQ GDV+   I  +G     
Sbjct: 238 YTFAEMIERASEDVTLYPGDVIGSGTVGTGCILELGTEEWLQDGDVVELTITGLGTLRNT 297

Query: 285 IEK 287
           ++K
Sbjct: 298 VKK 300


>UniRef50_A3Q487 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=1;
           Mycobacterium sp. JLS|Rep: Fumarylacetoacetate (FAA)
           hydrolase - Mycobacterium sp. (strain JLS)
          Length = 265

 Score =  113 bits (271), Expect = 7e-24
 Identities = 75/222 (33%), Positives = 115/222 (51%), Gaps = 8/222 (3%)

Query: 62  IPLSSVTLTAPIHGVDKILCIGLNYKDHCQEQNLTPPPVPMV-FSKFSSTIIGPDQPVRI 120
           + L  V L  PI     ++ +G+NY  H ++  +T  P   + F K  + IIG    V  
Sbjct: 37  LKLDDVRLLPPITPTSTVVGVGMNYWSHLEKLGVTERPKSTLGFLKPRAAIIGHGD-VLA 95

Query: 121 RTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLLG 180
              +T+++D+EVEL VV+ +  S        + V GYTV  D+SARD     + G  L  
Sbjct: 96  NPVITEQLDFEVELVVVLAQSVSHPGGRPT-EAVLGYTVGNDVSARDAAVPMSGGLDLFS 154

Query: 181 -KSMDTFCPLGPCVLTSDEVGAAVELRVSCSL--NGVLKQSSSTAQLVHSIPSLLHRISS 237
            K++    P+GP + T DE G + ++ V  SL  NG  +Q   T +++ SI   L  + +
Sbjct: 155 IKALGGTTPVGPWITTKDEFGGSGQIDVGISLRVNGEQRQHDRTGKMIFSIDECLDYVVA 214

Query: 238 VMTLVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIG 279
            M L  GD++ TGT  GVG   +   YLQ GDV+ +E+E +G
Sbjct: 215 RMPLAAGDIVFTGTTHGVGF--EDGRYLQAGDVVEAEVEGVG 254


>UniRef50_Q9YG48 Cluster: Fumarylacetoacetate hydrolase family
           protein; n=1; Aeropyrum pernix|Rep: Fumarylacetoacetate
           hydrolase family protein - Aeropyrum pernix
          Length = 286

 Score =  113 bits (271), Expect = 7e-24
 Identities = 65/190 (34%), Positives = 104/190 (54%), Gaps = 6/190 (3%)

Query: 82  IGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRIRTDVTKKVDWEVELCVVVGRE 141
           +G +Y +H +E  ++       FSK  +++ G   PV +   V++K D+E E+ +++G+ 
Sbjct: 82  VGRSYAEHAREMGMSKQIA--FFSKPVTSLTGHLNPVVV-PPVSEKPDYEGEIVIIIGKR 138

Query: 142 ASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLLGKSMDTFCPLGPCVLTSDEVGA 201
                  +A + +AGYT   DI+ R  Q   +M  + + K +DT+ P+GP     D    
Sbjct: 139 IKNASTAEAGKAIAGYTAGADITDRLLQ---DMMSWSMAKGLDTYGPVGPVATIIDSPDD 195

Query: 202 AVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPGDLILTGTPGGVGMYRQP 261
              L V   LNG   Q   T  ++ SIP ++ R+S++ TL PGD++ TGTP GVG  R+P
Sbjct: 196 LDGLCVHTWLNGEKVQRGCTGDMIVSIPDMVSRLSALATLRPGDIVFTGTPPGVGHARKP 255

Query: 262 PEYLQPGDVL 271
           P YL+ GD L
Sbjct: 256 PRYLRHGDEL 265


>UniRef50_A1HMI6 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=1;
           Thermosinus carboxydivorans Nor1|Rep:
           Fumarylacetoacetate (FAA) hydrolase - Thermosinus
           carboxydivorans Nor1
          Length = 295

 Score =  111 bits (267), Expect = 2e-23
 Identities = 73/213 (34%), Positives = 107/213 (50%), Gaps = 6/213 (2%)

Query: 44  RNGDLEKVKKLKSTKPATIPLSSVTLTAPIHGVDKILCIGLNYKDHCQE-QNLTPPPVPM 102
           RNG  EK   L+S     I  + V          KI  IGLNY DH  +     P   P 
Sbjct: 57  RNGGKEK---LESLSQYAISKNEVRYAPLYRHPSKIWGIGLNYVDHAGDLAEKAPTLAPA 113

Query: 103 VFSKFSSTIIGPDQPVRIRTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQD 162
            F+KF +TIIGP + ++I    ++K   E EL ++ G++   V E+D L  VAG+T   D
Sbjct: 114 SFAKFDTTIIGPGEEIKIPLQ-SEKTTGESELAIIFGKKCKDVEEKDWLNVVAGFTTIID 172

Query: 163 ISARDWQKEKNMGQFLLGKSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTA 222
           ++A D  +  N       K+ DTF   GP ++T DE+    +L V+  +NG +   +  +
Sbjct: 173 MTAEDILRI-NPRYLTRAKNFDTFLSFGPVLVTPDEIEDVNKLNVATVINGRIHARNVVS 231

Query: 223 QLVHSIPSLLHRISSVMTLVPGDLILTGTPGGV 255
            +      L+   S V T++PGD+ILTGTP  V
Sbjct: 232 NMTFPPAYLVSFHSKVATMLPGDIILTGTPRAV 264


>UniRef50_A0Y9R8 Cluster: 2-keto-4-pentenoate
           hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase;
           n=5; Gammaproteobacteria|Rep: 2-keto-4-pentenoate
           hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase -
           marine gamma proteobacterium HTCC2143
          Length = 223

 Score =  111 bits (267), Expect = 2e-23
 Identities = 70/200 (35%), Positives = 107/200 (53%), Gaps = 12/200 (6%)

Query: 78  KILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRIRTDVTKKVDWEVELCVV 137
           KI+C+G NY DH +E N   P  P++F K S+  +    P+ I TD       E+E+ V+
Sbjct: 23  KIVCVGRNYADHAKELNNPIPDRPLLFIKPSTAAVDMLLPINIPTD-RGCCHHELEMAVL 81

Query: 138 VGREASCVREEDALQHVAGYTVAQDISARDWQKE-KNMGQ-FLLGKSMDTFCPLGPCVLT 195
           +G+ +S V   +A   + G  +  D++ RD Q E K  G+ +   K+ D  CPL P    
Sbjct: 82  IGKRSSSVSSVEAKDAIVGVGLGLDLTLRDLQDELKAKGEPWERAKAFDGSCPLSPFSSV 141

Query: 196 SDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPGDLILTGTPGGV 255
            D       L ++   NG ++QS +T  ++  +  L+  IS   TL+PGD+ILTGTP GV
Sbjct: 142 GDI--DQQNLNITLLRNGTVQQSGNTRDMLFPVADLIADISRSFTLLPGDIILTGTPAGV 199

Query: 256 GMYRQPPEYLQPGDVLTSEI 275
           G     P Y  PGD +T+++
Sbjct: 200 G-----PLY--PGDTITAQL 212


>UniRef50_Q8EMH6 Cluster: 4-hydroxyphenylacetate degradation
           bifunctional isomerase : decarboxylase; n=2;
           Bacillaceae|Rep: 4-hydroxyphenylacetate degradation
           bifunctional isomerase : decarboxylase - Oceanobacillus
           iheyensis
          Length = 263

 Score =  110 bits (264), Expect = 5e-23
 Identities = 78/256 (30%), Positives = 125/256 (48%), Gaps = 21/256 (8%)

Query: 40  LQILRNGDLEKVKKLKSTKPATIPLSSVTLTAPIHGVDKILCIGLNYKDHCQEQNL---- 95
           +Q L+ G  +  +KL         L  ++L  PI+G   +    LNYK    E       
Sbjct: 11  VQQLKEGIYQPDQKLLKFDGKQCSLDDLSLDVPINGT--VYGTLLNYKGEYAELESSMNE 68

Query: 96  ----TPPPVPMVFSKFSSTIIGPDQPVRIRTDVTKKVDWEVELCVVVGREASCVREEDAL 151
               TPP  P+++ K  +T IG    + +   V +KV     L VV+G+ A  +R+E+AL
Sbjct: 69  DPYKTPPKAPILYIKPINTHIGYGMTIPLPEGV-EKVSIGAALGVVIGKPAKNIRKENAL 127

Query: 152 QHVAGYTVAQDISARDWQKEKNMGQFLLGKSMDTFCPLGPCVLTSDEVGAAVELRVSCSL 211
            +VAGYT+  D+S  +   E         K+ D FCP+GP VL  D +    EL +   +
Sbjct: 128 DYVAGYTIVNDVSIPN---ESYYRPAYKEKARDGFCPIGPWVLRRDAIENPNELGIRVYI 184

Query: 212 NGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPGDLILTGTPGGVGMYRQPPEYLQPGDVL 271
           NG +KQ ++T+ L+ S+  L+  ++  MTL  GD++L G P    + ++        D +
Sbjct: 185 NGEIKQENTTSNLIRSVEQLMEEVTDFMTLYEGDVLLVGVPENAPIAKE-------NDRV 237

Query: 272 TSEIEKIGAFDVRIEK 287
             EI+ IG    ++EK
Sbjct: 238 IIEIDNIGTLVNKVEK 253


>UniRef50_A6G0I9 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate
           decarboxylase; n=1; Plesiocystis pacifica SIR-1|Rep:
           5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase -
           Plesiocystis pacifica SIR-1
          Length = 287

 Score =  110 bits (264), Expect = 5e-23
 Identities = 75/228 (32%), Positives = 106/228 (46%), Gaps = 12/228 (5%)

Query: 51  VKKLKSTKPATIPLSSVTLTAPIHGVDKILCIGLNYKDHCQEQNLTPPPVPMVFSKFSST 110
           V + ++  PA        + AP     K+L IG NY  H +E     P  P+ F K  S 
Sbjct: 55  VAEAQALGPAQTLFEDQAVLAPPLAPTKVLAIGRNYAAHAKELGNEVPSSPLSFFKPPSC 114

Query: 111 IIGPDQPVRIRTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQK 170
           ++   QP+ +     + +D E EL +V+GR A  +   DA  HV  Y +  DIS RD Q+
Sbjct: 115 LLASGQPLSLPRGYAR-IDMEAELVLVIGRRARQIAAADAWAHVGAYLMGNDISCRDLQR 173

Query: 171 EKNMGQFLLGKSMDTFCPLGPCVLTSD--EVGAAVELRVSCSLNGVLKQSSSTAQLVHSI 228
                Q+   K  D F P+      S   E+     LRV   L   L Q   T+ ++  +
Sbjct: 174 SDK--QWTRAKGFDGFGPVSAFARLSPAAELPPVDALRVRGLLGDELVQDGPTSAMIFDV 231

Query: 229 PSLLHRISSVMTLVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIE 276
           P+LL  +S+ MTL  GDLI TGTP GV         L+PG V   E++
Sbjct: 232 PTLLEHLSACMTLEVGDLIFTGTPAGVSA-------LEPGMVTRVELD 272


>UniRef50_A7EGL0 Cluster: 2-keto-4-pentenoate hydratase; n=6;
           Ascomycota|Rep: 2-keto-4-pentenoate hydratase -
           Sclerotinia sclerotiorum 1980
          Length = 241

 Score =  110 bits (264), Expect = 5e-23
 Identities = 72/224 (32%), Positives = 120/224 (53%), Gaps = 12/224 (5%)

Query: 71  APIHGVDKILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRIRTDVTKKVD- 129
           +P     K++CIG NY DH  E N + P  P  F K  S+I+ P+    IR    K VD 
Sbjct: 13  SPFKSASKVVCIGRNYADHITELNNSKPKQPFFFLKPPSSILPPNGGAVIRP---KGVDL 69

Query: 130 -WEVELCVVVGREASCVR---EEDALQHVAGYTVAQDISARDWQKE-KNMG-QFLLGKSM 183
            +EVEL +++G++   +    E++A   +  Y ++ D++AR+ Q E K  G  + + K  
Sbjct: 70  HYEVELALIMGKQLKNLEPENEKEAYDSIESYAMSIDMTARNAQNEAKKKGLPWDIAKGF 129

Query: 184 DTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVP 243
           DTF P+   +++  ++       V  ++N   +Q  ST  +++ IP +L  IS VMTL  
Sbjct: 130 DTFLPMSN-IISKSQIPDPHNATVWLTVNNEHRQKDSTELMLYRIPRILSDISKVMTLEK 188

Query: 244 GDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIGAFDVRIEK 287
           GD++LTGTP GVG  + P + ++ G  +  +    G  +V +E+
Sbjct: 189 GDIVLTGTPKGVGSVK-PGDVMRVGISVGGKELTEGKIEVAVEE 231


>UniRef50_Q6N2Q7 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=11;
           Bradyrhizobiaceae|Rep: Fumarylacetoacetate (FAA)
           hydrolase - Rhodopseudomonas palustris
          Length = 233

 Score =  109 bits (263), Expect = 6e-23
 Identities = 70/229 (30%), Positives = 113/229 (49%), Gaps = 11/229 (4%)

Query: 59  PATIPLSSVTLTAPIHGVDKILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPV 118
           P   P  +V  T+    V +I C+G NY +H +E        P  F+K +  ++ PD   
Sbjct: 10  PPPQPTLAVAGTSDRFPVRRIWCVGRNYLEHVREMGNDERQPPFFFAKHAD-MVTPDGAT 68

Query: 119 RIRTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQ--KEKNMGQ 176
                +TK +  EVEL V +      +  E AL HV GY V  D++ RD Q    K    
Sbjct: 69  IPYPPLTKDLHHEVELVVALKSGRLNIPVERALDHVWGYAVGIDLTRRDLQIASRKKEQP 128

Query: 177 FLLGKSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRIS 236
           + +GKS D   P G  +  + E+G     ++  S+NG  +Q+   ++++ ++P ++ ++S
Sbjct: 129 WEIGKSFDASAPCG-ALRPASEIGHPATGKIWLSVNGTERQTGDLSEMIWNVPEIIAKLS 187

Query: 237 SVMTLVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIGAFDVRI 285
           + + L  GD+I+TGTP GV         L PGD +   I+ IG  +V I
Sbjct: 188 AQVELAAGDIIMTGTPAGVAA-------LSPGDAIACGIDGIGTLNVTI 229


>UniRef50_Q1EC44 Cluster: IP02096p; n=6; Endopterygota|Rep: IP02096p
           - Drosophila melanogaster (Fruit fly)
          Length = 236

 Score =  109 bits (263), Expect = 6e-23
 Identities = 66/184 (35%), Positives = 104/184 (56%), Gaps = 4/184 (2%)

Query: 78  KILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRIRTDVTKKVDWEVELCVV 137
           KI+ + LNY D    +N+  P  P+VF K +S+ +   QP+ +   V  KV +EVEL VV
Sbjct: 33  KIVGVALNYMDVVLARNVPVPKEPLVFLKPTSSYLQEGQPI-VLPKVFTKVAYEVELGVV 91

Query: 138 VGREASCVREEDALQHVAGYTVAQDISAR-DWQKEKNMGQ-FLLGKSMDTFCPLGPCVLT 195
           +G+    V + DA+ +VAGY +A D++A+ +    +  G  + LGK  DT  P+   +  
Sbjct: 92  IGKPCKNVSKADAMSYVAGYCLALDLTAQCNLGPARAAGHPWTLGKGFDTSTPVSQFI-P 150

Query: 196 SDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPGDLILTGTPGGV 255
            ++V     L +  ++NG LKQ+  TA L+  +P ++  +S  MTL   DLILTGTP G 
Sbjct: 151 IEKVTDPHNLPLWLTVNGDLKQNGCTADLIFKVPDIISYVSKYMTLEANDLILTGTPNGA 210

Query: 256 GMYR 259
             ++
Sbjct: 211 DAFK 214


>UniRef50_A0GN11 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=1;
           Burkholderia phytofirmans PsJN|Rep: Fumarylacetoacetate
           (FAA) hydrolase - Burkholderia phytofirmans PsJN
          Length = 346

 Score =  109 bits (261), Expect = 1e-22
 Identities = 61/181 (33%), Positives = 98/181 (54%), Gaps = 5/181 (2%)

Query: 101 PMVFSKFSSTIIGPDQPVRIRTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVA 160
           P  F + +S I  PD  +   +  T+++DWE+EL +V+GR    V  EDA   VA   + 
Sbjct: 151 PYFFQRPNSCIAPPDGEIHAESG-TEELDWELELGIVIGRRGRHVAREDAPNFVAACLIL 209

Query: 161 QDISARD--WQKEKNMGQFLLGKSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQS 218
            D++ R   ++++     +L GK M    P GP ++ +  +G    LR+  S+NG + Q 
Sbjct: 210 NDVTDRALIYRQDFPGADWLRGKGMPASMPAGPYLVPASVIGEIDALRLRLSVNGEVMQD 269

Query: 219 SSTAQLVHSIPSLLHRISSVMTLVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKI 278
                ++  +P L+  +SS + L PGD+I TGTP G G  R    +LQ GDV+ +EI+ +
Sbjct: 270 ELAGDMILDVPRLIEYLSSRVELRPGDVIATGTPAGTGAER--GRFLQDGDVIRAEIDGL 327

Query: 279 G 279
           G
Sbjct: 328 G 328


>UniRef50_A0UKA6 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=6;
           Burkholderia|Rep: Fumarylacetoacetate (FAA) hydrolase -
           Burkholderia multivorans ATCC 17616
          Length = 426

 Score =  108 bits (259), Expect = 2e-22
 Identities = 71/214 (33%), Positives = 110/214 (51%), Gaps = 10/214 (4%)

Query: 51  VKKLKSTKPATIPLSSVTLTAPIHGVDKILCIGLNYKDHCQEQNLTPPPVP--MVFSKFS 108
           V++L      TIP + V    P+    + +C G NY+ H  E  + P      M+F+K  
Sbjct: 151 VERLAMIDGPTIPEADVQWLPPVTANQQFVCQGANYRRHMIESGMDPDAKQFNMIFTKAP 210

Query: 109 STIIGPDQPVRIRTDVTKKVDWEVELCVVVGREASC---VREEDALQHVAGYTVAQDISA 165
           S I+  D  V ++    + +D+E+EL +V+ R+ +    V + +  ++VAG  +  D SA
Sbjct: 211 SCIVAADSRV-VKPRHVRFLDYEIELGLVLKRDITRHQPVTDANLHEYVAGIAIVNDYSA 269

Query: 166 RDWQKEKNMGQFLLGKSMDTFCPLGP--CVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQ 223
           RD Q  +   QF  GKS  TF P+GP  C+L   +      L ++ S+NG ++Q  STA 
Sbjct: 270 RDVQIPQM--QFYKGKSFRTFGPVGPYLCLLERHDFPKLKTLELTLSVNGTVRQQDSTAN 327

Query: 224 LVHSIPSLLHRISSVMTLVPGDLILTGTPGGVGM 257
           LV+     L  +S V  L  GDL+ TGTP G  +
Sbjct: 328 LVYGPAETLTELSGVHDLGAGDLLATGTPAGCAL 361


>UniRef50_A0QDN9 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate
           isomerase; n=4; Actinomycetales|Rep:
           2-hydroxyhepta-2,4-diene-1,7-dioate isomerase -
           Mycobacterium avium (strain 104)
          Length = 313

 Score =  108 bits (259), Expect = 2e-22
 Identities = 66/212 (31%), Positives = 112/212 (52%), Gaps = 11/212 (5%)

Query: 62  IPLSSVTLTAPIHGVDKILCIGLNYKDHCQEQNLTPPPVPMVF-SKFSSTIIGPDQPVRI 120
           +P+  + L +P+    +++    N+  H ++  + P  +P+ F  K S +I GP   + +
Sbjct: 50  VPVEGLNLLSPVTAPCRVVAQMTNFASHVKDAGMDPNTIPLTFFRKASGSITGPFDDI-V 108

Query: 121 RTDVTKKVDWEVELCVVVGRE---ASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQF 177
           + D  + +D+EVE+ +V+GRE    + V E +   + AG  V  D+SARD Q  K   QF
Sbjct: 109 KPDHVRFLDYEVEIGLVIGRELPVGAAVSEANLADYTAGAVVTNDVSARDIQLPKT--QF 166

Query: 178 LLGKSMDTFCPLGPC--VLTSDEVGAAVELRVSCSLNGVLKQSSST-AQLVHSIPSLLHR 234
              KS  TF P+GP   +L +DE+    +LR+   +NG ++Q       +++     L  
Sbjct: 167 YESKSYPTFTPVGPALVLLDADELKRFGDLRLQLRVNGQVRQDMRVDGDMIYPPVQALQA 226

Query: 235 ISSVMTLVPGDLILTGTPGGVGMYRQPPEYLQ 266
           ++    L PGDL+LTGTP G  +   PP+ +Q
Sbjct: 227 LARFQRLDPGDLVLTGTPVGTAL-SAPPKPVQ 257


>UniRef50_Q6D4M4 Cluster: Fumarylacetoacetate hydrolase family
           protein; n=25; Enterobacteriaceae|Rep:
           Fumarylacetoacetate hydrolase family protein - Erwinia
           carotovora subsp. atroseptica (Pectobacterium
           atrosepticum)
          Length = 218

 Score =  107 bits (258), Expect = 2e-22
 Identities = 64/183 (34%), Positives = 98/183 (53%), Gaps = 4/183 (2%)

Query: 76  VDKILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRIRTDVTKKVDWEVELC 135
           V+K++C+G NY +H +E     P  P++F K  + +    QPV I  ++   V  EVEL 
Sbjct: 16  VNKVVCVGSNYSEHIKEMGSATPSEPVLFIKPETALCDLRQPVAIPKNLGS-VHHEVELA 74

Query: 136 VVVGREASCVREEDALQHVAGYTVAQDISARDWQKE-KNMGQ-FLLGKSMDTFCPLGPCV 193
           V++G       EE   + +AGY VA D++ RD Q E K  GQ +   K+ D  CP+   +
Sbjct: 75  VLIGTPLKQANEERVARAIAGYGVALDLTLRDLQSEFKKAGQPWEKAKAFDGSCPISGFI 134

Query: 194 LTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPGDLILTGTPG 253
             + E G   +  +   +N  ++Q  +T  ++ SI  L+  +S   TL  GD+ILTGTP 
Sbjct: 135 PVA-EFGDPQQTELGVKVNDEVRQQGNTRDMITSILPLIAYMSRFFTLRAGDIILTGTPK 193

Query: 254 GVG 256
           GVG
Sbjct: 194 GVG 196


>UniRef50_UPI000023E361 Cluster: hypothetical protein FG10641.1;
           n=1; Gibberella zeae PH-1|Rep: hypothetical protein
           FG10641.1 - Gibberella zeae PH-1
          Length = 230

 Score =  107 bits (257), Expect = 3e-22
 Identities = 64/173 (36%), Positives = 92/173 (53%), Gaps = 4/173 (2%)

Query: 103 VFSKFSSTIIGPDQPVRIRTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQD 162
           VFS  S  ++ P Q       +    D+E EL VV+GR A  V +E+A+++V GYT A D
Sbjct: 47  VFSGLS--VLKPGQKTGETAVIDDCGDYEAELAVVIGRAAKNVTKEEAMEYVLGYTAAND 104

Query: 163 ISARDWQKEKNMGQFLLGKSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTA 222
           IS+R  Q  ++  Q+   K  D  CPLGP +++ D V       +       + Q     
Sbjct: 105 ISSRTSQFGQS--QWCFSKGFDGSCPLGPALVSKDLVPDPSMFNIRGLKKDQVLQDCGAD 162

Query: 223 QLVHSIPSLLHRISSVMTLVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEI 275
            L+  IP+L+  +S   TL+PG +ILTGTP GVG+ RQP   +  GD  + EI
Sbjct: 163 DLIFDIPTLISFLSQGTTLLPGTVILTGTPAGVGVGRQPKVTISDGDEFSVEI 215


>UniRef50_Q4P0N7 Cluster: Putative uncharacterized protein; n=1;
           Ustilago maydis|Rep: Putative uncharacterized protein -
           Ustilago maydis (Smut fungus)
          Length = 313

 Score =  107 bits (256), Expect = 4e-22
 Identities = 60/177 (33%), Positives = 98/177 (55%), Gaps = 5/177 (2%)

Query: 98  PPVPMVFSKFSSTIIGPDQPVRIRTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGY 157
           P +P++F K  ST+ GP + + I   V ++ D+EVEL VV+GR+   V   +A+  + GY
Sbjct: 108 PVIPILFYKPISTLSGPGRDIVIPPCVAEQADYEVELVVVLGRDIKDVSPVEAMDAILGY 167

Query: 158 TVAQDISARDWQKEKNMGQFLLGKSMDTFCPLGPCVLTSDE---VGAAVELRVSCSLNGV 214
           T++ D+SAR   +   + Q+ LGKS D + P+GPC++++     +     + ++  LN  
Sbjct: 168 TLSNDVSAR--TRMFAVPQWGLGKSFDGWLPIGPCLVSASNPRGITNRDNIHLTTKLNNR 225

Query: 215 LKQSSSTAQLVHSIPSLLHRISSVMTLVPGDLILTGTPGGVGMYRQPPEYLQPGDVL 271
           + Q  +T+ ++      L  +S   TL  G L++ GTP G G  RQP   L  GD L
Sbjct: 226 IMQDGNTSDMLWKTAETLAELSKGTTLEAGSLLIMGTPPGEGFKRQPKVCLNHGDTL 282


>UniRef50_Q1AX83 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate
           decarboxylase; n=1; Rubrobacter xylanophilus DSM
           9941|Rep: 5-oxopent-3-ene-1,2,5-tricarboxylate
           decarboxylase - Rubrobacter xylanophilus (strain DSM
           9941 / NBRC 16129)
          Length = 295

 Score =  106 bits (254), Expect = 7e-22
 Identities = 74/227 (32%), Positives = 110/227 (48%), Gaps = 11/227 (4%)

Query: 62  IPLSSVTLTAPIHGVDKILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRIR 121
           IP +     AP     KI+ + L Y+   +E     PP P  F K  + + G    VR  
Sbjct: 42  IPEAGARYLAPAEPT-KIIAVHLTYRSRVEEYGARVPPEPSYFLKPPTALNGHRGVVRWP 100

Query: 122 TDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLLGK 181
              T+ +++E EL V+VGR    V  E+AL  VAGYT A D+   D+ +  + G  L  K
Sbjct: 101 AG-TRFLNYEGELAVIVGRRMKGVGMEEALSCVAGYTCANDVGLHDF-RHADRGSMLRVK 158

Query: 182 SMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTL 241
             D F PLGP V+ +       +  +   LNG + Q      L+  +   L  +  ++TL
Sbjct: 159 GQDGFLPLGPEVVPASRFDPE-DFALRTYLNGEVVQEGGAEDLLFGVAYQLADLCRLITL 217

Query: 242 VPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIGAFDVRIEKF 288
            PGD++LTGTP       +P   ++PGDV+  EIE IG     +E++
Sbjct: 218 EPGDVVLTGTPAN----SRP---MRPGDVVEVEIEGIGRLSNTVEEW 257


>UniRef50_A7D0K4 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=1;
           Halorubrum lacusprofundi ATCC 49239|Rep:
           Fumarylacetoacetate (FAA) hydrolase - Halorubrum
           lacusprofundi ATCC 49239
          Length = 273

 Score =  105 bits (252), Expect = 1e-21
 Identities = 68/227 (29%), Positives = 109/227 (48%), Gaps = 10/227 (4%)

Query: 62  IPLSSVTLTAPIHGVDKILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRIR 121
           +P + ++  AP+    K+  IGLNY +H  + +   P  P  F K SS + GP  P+R+ 
Sbjct: 56  VPAADISFGAPLESFGKLWGIGLNYAEHAGDLDEQRPDEPASFMKPSSVLTGPSGPIRLP 115

Query: 122 TD-VTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLLG 180
            +  +++V  E EL VV+GR    V E      VAG+    D++A D   ++N       
Sbjct: 116 PESQSERVTAEAELAVVMGRTCRNVEEAAFEDVVAGFLPVIDMTAED-VLQRNPRFLTRS 174

Query: 181 KSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMT 240
           KS DTF   G  +   +E      L V   +NG ++  +    ++     ++   S VMT
Sbjct: 175 KSYDTFLVPGAALAVPEEPLDLDALSVQTEVNGEIEAENEIRNMLFPPSEIVSFHSDVMT 234

Query: 241 LVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIGAFDVRIEK 287
           L PGDL  TGTPG          +++PGD + + +E IG  +  + +
Sbjct: 235 LEPGDLFSTGTPGAA--------HIEPGDEVRAVVESIGTVEAPVTR 273


>UniRef50_Q1ATV1 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=3;
           Actinobacteria (class)|Rep: Fumarylacetoacetate (FAA)
           hydrolase - Rubrobacter xylanophilus (strain DSM 9941 /
           NBRC 16129)
          Length = 349

 Score =  104 bits (250), Expect = 2e-21
 Identities = 65/183 (35%), Positives = 97/183 (53%), Gaps = 7/183 (3%)

Query: 101 PMVFSKFSSTIIGPDQPVRIRTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVA 160
           P +F    + + GP   V +  +  +  DWE+E   V+GR    V  E AL  VAGYT+A
Sbjct: 145 PYLFLGSPTALCGPYDDVVLPAEGDQH-DWELEFAAVIGRSGRHVPPERALDLVAGYTIA 203

Query: 161 QDISARD--WQKE-KNMG-QFLLGKSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLK 216
            DI+ RD  ++ + K +G  +L  K+  TF P GP ++  + VG    LR++  LNG   
Sbjct: 204 NDITTRDLVYRPDLKAIGTDWLRSKNAPTFLPTGPYIVPKEFVGDTSGLRITLRLNGETM 263

Query: 217 QSSSTAQLVHSIPSLLHRISSVMTLVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIE 276
           Q  S + ++  +  L+   SS + L PGDLILTG+P G G Y     +L  GDV+   + 
Sbjct: 264 QDESASDMIFDVARLVSYASSRVLLRPGDLILTGSPAGNGSYW--GRFLGEGDVMEGTVT 321

Query: 277 KIG 279
            +G
Sbjct: 322 GLG 324


>UniRef50_Q0K430 Cluster: 2-Keto-4-pentenoate
           hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase;
           n=3; Burkholderiales|Rep: 2-Keto-4-pentenoate
           hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase -
           Ralstonia eutropha (strain ATCC 17699 / H16 / DSM 428 /
           Stanier 337)(Cupriavidus necator (strain ATCC 17699 /
           H16 / DSM 428 / Stanier337))
          Length = 301

 Score =  104 bits (250), Expect = 2e-21
 Identities = 71/244 (29%), Positives = 118/244 (48%), Gaps = 20/244 (8%)

Query: 61  TIPLSSVTLTAPIHGVDKILCIGLNYKDH------CQEQNLTPPPV-----PMVFSKFSS 109
           T+  + +    P+     I   G NY+DH          +LT  P      P  F K   
Sbjct: 60  TMEPAQIRFLPPLSQPGVIYGAGANYRDHVVAMAKAVNMDLTTDPKADGVPPWHFIKAGR 119

Query: 110 TIIGPDQPVRIRTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQ 169
             +   +        T+ +DWE EL VV+G+    +   DAL  VAGYT+A D+SARD  
Sbjct: 120 GTLSAHRQALPYPSHTRMLDWEAELAVVIGKACRNISPGDALDCVAGYTIANDLSARDNL 179

Query: 170 KEKNMG-------QFLLGKSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTA 222
           + + +         ++  K  +  CPLGP +  +  V +   L +   +N  LKQ+S+T+
Sbjct: 180 RREQVDASSPFRFDWIGHKCFEGSCPLGPYLTPAAFVASPEALDIKLWVNDELKQNSNTS 239

Query: 223 QLVHSIPSLLHRISSVMTLVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIGAFD 282
             ++++   +  +S  +TL PGD++LTGTP GVGM  +   +L+ GD +   I+ +G  +
Sbjct: 240 NHLYTVAEQIAYLSERLTLYPGDVLLTGTPAGVGM--ESGVFLKRGDSIRVWIDGLGELE 297

Query: 283 VRIE 286
             ++
Sbjct: 298 TSLQ 301


>UniRef50_Q7VXR8 Cluster: Putative hydrolase; n=1; Bordetella
           pertussis|Rep: Putative hydrolase - Bordetella pertussis
          Length = 316

 Score =  104 bits (249), Expect = 3e-21
 Identities = 65/191 (34%), Positives = 103/191 (53%), Gaps = 7/191 (3%)

Query: 100 VPMVFSKFSSTIIGPDQPVRIRTDVTKKVDWEVELCVVVGREASC-VREEDALQHVAGYT 158
           +P  F K +S +   D  V     V    D+EVE+  V+G         E AL+HV GYT
Sbjct: 127 MPAGFIKIASVMTPHDSAVARPCGVLA-FDYEVEVAAVLGGPVPLGTPPERALEHVFGYT 185

Query: 159 VAQDISARDWQKEKNMGQFL-LGKSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQ 217
           +  D+SAR+W + +   Q + +GK+     PLGP ++T+DEV    +L +S S+NG  +Q
Sbjct: 186 LFNDLSAREWARAEMKNQMIAMGKNFPGAGPLGPWIVTADEVPDPAQLELSLSVNGEPRQ 245

Query: 218 SSSTAQLVHSIPSLLHRISSVMTLVPGDLILTGTPGGVGMYRQP---PEYLQPGDVLTSE 274
             S  +++ +   L+   S +  L  G+LI +GTP G  + R+P   P +L+PGD++ + 
Sbjct: 246 HGSCKEMIFTFAQLIAHWSRI-GLGAGELIASGTPEGGAISRKPDPAPFFLKPGDIVEAH 304

Query: 275 IEKIGAFDVRI 285
             +IG    RI
Sbjct: 305 CPQIGTLRTRI 315


>UniRef50_A6T028 Cluster: Faa-hydrolase family protein; n=7;
           Proteobacteria|Rep: Faa-hydrolase family protein -
           Janthinobacterium sp. (strain Marseille) (Minibacterium
           massiliensis)
          Length = 265

 Score =  104 bits (249), Expect = 3e-21
 Identities = 67/207 (32%), Positives = 101/207 (48%), Gaps = 10/207 (4%)

Query: 56  STKPATIPLSSVTLTAPIHGVDKILCIGLNYKDHCQEQNLTPP-PVPMVFSKFSSTI--I 112
           S    TIP+       P+    +I CIG NY  H +E    P    P  F K S  I  +
Sbjct: 40  SVAQPTIPIVGSNEQFPVR---RIYCIGRNYAAHAREMGSDPTREPPFFFQKPSDAIQYV 96

Query: 113 GPDQPV-RIRTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQK- 170
            P + V      +TK   +E+EL   + +    +  E+ALQHV GY V  D++ RD Q  
Sbjct: 97  APGKVVDHPYPTLTKNYHYEIELVAAINKGGKNISVENALQHVFGYAVGLDMTRRDLQAA 156

Query: 171 -EKNMGQFLLGKSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIP 229
            +K    + +GKS D   P+GP    +  +G   E ++   +NG +KQS+   Q++ S+ 
Sbjct: 157 MKKEEKPWEIGKSFDMSAPIGPLHPVAS-IGNFTEGKIWLKVNGQVKQSADLKQMIWSVA 215

Query: 230 SLLHRISSVMTLVPGDLILTGTPGGVG 256
             +  +S    L+PGD+I +GTP  VG
Sbjct: 216 EQISNLSKAFELMPGDIIYSGTPENVG 242


>UniRef50_Q397B1 Cluster: Fumarylacetoacetate (FAA) hydrolase;
           n=123; Proteobacteria|Rep: Fumarylacetoacetate (FAA)
           hydrolase - Burkholderia sp. (strain 383) (Burkholderia
           cepacia (strain ATCC 17760/ NCIB 9086 / R18194))
          Length = 252

 Score =  103 bits (248), Expect = 4e-21
 Identities = 63/209 (30%), Positives = 100/209 (47%), Gaps = 10/209 (4%)

Query: 76  VDKILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRIRTDVTKKVDWEVELC 135
           V ++ C+G NY DH +E    P   P  F    +  I P         +T  +  E+EL 
Sbjct: 45  VRRVFCVGRNYADHAREMGADPDREPPFFFTKPADAIVPASGTVAYPPLTNDLHHEIELV 104

Query: 136 VVVGREASCVREEDALQHVAGYTVAQDISARDWQKE-KNMGQ-FLLGKSMDTFCPLGPCV 193
           V +G++   +   DAL HV GY V  D++ RD Q E K + + +   K  D   P+   +
Sbjct: 105 VAIGKDGRAIDPADALSHVWGYGVGIDLTRRDLQAEAKKLSRPWDWAKGFDASGPV-TAL 163

Query: 194 LTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPGDLILTGTPG 253
             +   G     R+  ++NG  +Q    A ++ ++P ++  +S  + L  GDLI TGTP 
Sbjct: 164 RAASATGHPATGRIWLAVNGDTRQQGDLADMIWAVPDVIAYVSRSVELKAGDLIFTGTPA 223

Query: 254 GVGMYRQPPEYLQPGDVLTSEIEKIGAFD 282
           GVG        LQPGD +T  ++ +  F+
Sbjct: 224 GVGA-------LQPGDRVTGGVDGVATFE 245


>UniRef50_Q89QI2 Cluster: Bll3146 protein; n=11; Proteobacteria|Rep:
           Bll3146 protein - Bradyrhizobium japonicum
          Length = 262

 Score =  103 bits (247), Expect = 5e-21
 Identities = 66/202 (32%), Positives = 101/202 (50%), Gaps = 5/202 (2%)

Query: 61  TIPLSSVTLTAPIHGVDKILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRI 120
           T+ LS V L AP     KI+ +  N+     + N   PP P+   K +++I  P   +R 
Sbjct: 45  TLALSEVELLAPC-APSKIVALWNNFHALAAKLNQPEPPEPLYLLKATTSIAAPGAVIRR 103

Query: 121 RTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARD-WQKEKNMGQFLL 179
            +    K  +E EL +V+GR  + V   +A   + GYT   DI+A D    +    Q+  
Sbjct: 104 PSYYDGKTTYEGELGIVIGRTCARVSPGEADSFIFGYTCVNDITANDILTSDPTFPQWAR 163

Query: 180 GKSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVM 239
            K +D + P GP + T  +     +L V   LNG  +Q+   + ++ S   L+ RIS  M
Sbjct: 164 AKGIDDYGPFGPVIATGLD---PAKLVVRTILNGAERQNYPISDMIFSAQELVSRISHDM 220

Query: 240 TLVPGDLILTGTPGGVGMYRQP 261
           TL+PGDLI  GT  GVG+ ++P
Sbjct: 221 TLLPGDLIAVGTSVGVGVMKEP 242


>UniRef50_Q72P81 Cluster: Fumarylacetoacetate hydrolase family
           protein; n=2; Leptospira interrogans|Rep:
           Fumarylacetoacetate hydrolase family protein -
           Leptospira interrogans serogroup Icterohaemorrhagiae
           serovarcopenhageni
          Length = 316

 Score =  103 bits (247), Expect = 5e-21
 Identities = 82/270 (30%), Positives = 132/270 (48%), Gaps = 22/270 (8%)

Query: 4   VQFSYKDSPKNIRVGYLEGDDIVDINKADSSLPTTLLQILRNGDLEKVKKLKSTKPATIP 63
           ++F  K+S   I+ G +E D I+ ++  D S     L+ L+       KK K  K   IP
Sbjct: 6   IRFKKKNS---IQWGKIEEDKILTLDCGDLSTKD-FLEFLK-------KKKKYPKQKLIP 54

Query: 64  LSSVTLTAPIHGVDKILCIGLNYKDHCQEQNLTP--PPVPMVFSKFSSTIIGPDQPVRIR 121
           +  V++ +PI    +I+C G NY+ H  E  L P      + F+K  +++  P   V IR
Sbjct: 55  IQEVSVLSPITSPCQIICQGANYRQHQIESGLDPDDKTYNLFFTKSDASLSPPIGKV-IR 113

Query: 122 TDVTKKVDWEVELCVVVGREASC---VREEDALQHVAGYTVAQDISARDWQKEKNMGQFL 178
               K +D+E+EL  V G+       +  +   +++A + +A DISARD Q  +   Q+ 
Sbjct: 114 PSHVKLLDYEIELGFVFGKSFDSTLKLNSKSIREYIAAFFMANDISARDVQLPQM--QWY 171

Query: 179 LGKSMDTFCPLGP--CVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRIS 236
            GKS  TFCP GP   VL   +      L ++  +N  ++Q  S + LV      +  +S
Sbjct: 172 KGKSYRTFCPTGPYLSVLDPGDFDLLDSLELTLLVNSQIRQKDSASNLVFKPLESVLELS 231

Query: 237 SVMTLVPGDLILTGTPGGVGMYRQPPEYLQ 266
               +  GD++LTGTP G  + R P + +Q
Sbjct: 232 QFCNISTGDVLLTGTPSGCAL-RAPGKLIQ 260


>UniRef50_Q2G539 Cluster: 5-carboxymethyl-2-hydroxymuconate
           delta-isomerase; n=5; Bacteria|Rep:
           5-carboxymethyl-2-hydroxymuconate delta-isomerase -
           Novosphingobium aromaticivorans (strain DSM 12444)
          Length = 296

 Score =  103 bits (247), Expect = 5e-21
 Identities = 62/202 (30%), Positives = 107/202 (52%), Gaps = 12/202 (5%)

Query: 78  KILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRIRTDVTKKVDWEVELCVV 137
           KI+C+ LNY    QE     PP P  F K   T +   +   +R +  K +++E E+ +V
Sbjct: 47  KIICVHLNYHSRVQEFITKLPPAPTYFQK-PLTALNTHKGAIVRPERCKWLNYEGEIAIV 105

Query: 138 VGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLLGKSMDTFCPLGPCVLTSD 197
           +G+    +   +A  ++ GY+VA D    D+ ++ + G  L  K  DT CP+GP ++T  
Sbjct: 106 IGKTCRNISPAEAGDYILGYSVANDYGLHDF-RDTDAGSMLRVKGSDTLCPIGPGLVTGW 164

Query: 198 EVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPGDLILTGTPGGVGM 257
           +     +  +   +NGVLKQ  +T+ +   +  L+  I+  +TL PGD++L+GTP     
Sbjct: 165 DFR---DKMIRTYVNGVLKQEDNTSNMEWDMHYLVADIARTITLEPGDVLLSGTPAN--- 218

Query: 258 YRQPPEYLQPGDVLTSEIEKIG 279
             +P   +Q GDV+  E++ +G
Sbjct: 219 -SRP---VQIGDVVEVEVDGLG 236


>UniRef50_A4CE53 Cluster: 2-keto-4-pentenoate
           hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase;
           n=1; Pseudoalteromonas tunicata D2|Rep:
           2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic
           acid hydratase - Pseudoalteromonas tunicata D2
          Length = 221

 Score =  103 bits (247), Expect = 5e-21
 Identities = 62/181 (34%), Positives = 97/181 (53%), Gaps = 4/181 (2%)

Query: 78  KILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRIRTDVTKKVDWEVELCVV 137
           K +CIG NY++H  E N   P  PM+F K SS+ +     + +   + +   +E EL ++
Sbjct: 18  KAVCIGRNYREHAAELNNAVPDSPMLFIKPSSSFVAFKGQIPLAQRLGEH-HYEAELALL 76

Query: 138 VGREASCVREEDALQHVAGYTVAQDISARDWQKE-KNMGQ-FLLGKSMDTFCPLGPCVLT 195
           +G+  S   E D  Q V G  VA D++ R+ Q E K+ G  +   K+ D  C + P +  
Sbjct: 77  IGQTISASTELDLQQQVIGIGVAMDLTLRNVQAELKSKGHPWEKAKAYDNSCIVSPFIQI 136

Query: 196 SDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPGDLILTGTPGGV 255
           +++      L  + S+N  ++Q   T+++V SI  LL  I    TL PGD++LTGTP GV
Sbjct: 137 TEQTDFN-NLEFNLSINNEIRQIGHTSEMVFSIVQLLDEIRQYFTLQPGDIVLTGTPKGV 195

Query: 256 G 256
           G
Sbjct: 196 G 196


>UniRef50_Q7PYH5 Cluster: ENSANGP00000019097; n=2; Culicidae|Rep:
           ENSANGP00000019097 - Anopheles gambiae str. PEST
          Length = 232

 Score =  103 bits (247), Expect = 5e-21
 Identities = 67/203 (33%), Positives = 103/203 (50%), Gaps = 8/203 (3%)

Query: 63  PLSSVTLTAPIHGVDKILCIGLNYKDHCQEQNLTPPPVPMVFSK---FSSTIIGPDQPVR 119
           P    T +  +    KI+  G+NYK+  +  N   P  P++F K    S+   G    +R
Sbjct: 9   PSKMPTTSKFLQSTRKIIGAGVNYKEILRLTNSPKPDAPVIFFKPISGSTGSTGTPPTIR 68

Query: 120 IRTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDW---QKEKNMGQ 176
           I       +++E EL V++GR  + V  + A+ +V GY +A D++  D+    + K +  
Sbjct: 69  IPRVFGGVINFEAELGVIIGRRCANVPTDQAMAYVGGYCLALDMTGMDFILDARPKGL-P 127

Query: 177 FLLGKSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRIS 236
           + LGK  DT  P+   V  +D +    ++RV C +NGV KQ  ST  L+  I  L+  +S
Sbjct: 128 WCLGKGFDTSTPVSALVQRAD-LPNPDDVRVWCEVNGVRKQDDSTRNLIFPIAELIAYVS 186

Query: 237 SVMTLVPGDLILTGTPGGVGMYR 259
             MTL   DL+LTGTP G G  R
Sbjct: 187 RFMTLEENDLLLTGTPAGAGPVR 209


>UniRef50_A6W1E0 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=1;
           Marinomonas sp. MWYL1|Rep: Fumarylacetoacetate (FAA)
           hydrolase - Marinomonas sp. MWYL1
          Length = 235

 Score =  102 bits (245), Expect = 9e-21
 Identities = 62/191 (32%), Positives = 103/191 (53%), Gaps = 7/191 (3%)

Query: 73  IHGVDKILCIGLNYKDHCQEQNLTPP-PVPMVFSKFSSTII--GPDQPVRIRTDV-TKKV 128
           ++ V ++ C+G NY +H +E    P    P  F+K SS ++  G  +   I   + T + 
Sbjct: 21  VYPVGRVYCVGRNYAEHSKEMGDDPERDPPFFFAKDSSCVVPAGFSESTLITYPMATSQF 80

Query: 129 DWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKE-KNMGQ-FLLGKSMDTF 186
           ++EVEL + +G+    +  + + + + GY V  D++ RD Q + K  G+ + +GKS D  
Sbjct: 81  EYEVELVIAIGKGGRNLTLQQSREAILGYAVGLDMTRRDLQSQAKKKGRPWEVGKSFDES 140

Query: 187 CPLGPCVLTSDEVGAAV-ELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPGD 245
            P+ P +L +D +   V +  +   +NG LKQ S    L  SI  ++ ++S V  L PGD
Sbjct: 141 APISPILLKTDLLADNVSKAEIGLKVNGDLKQISHVTNLTWSIEEVICKLSEVFELRPGD 200

Query: 246 LILTGTPGGVG 256
           LI+TGTP  VG
Sbjct: 201 LIMTGTPENVG 211


>UniRef50_A3UWQ7 Cluster: Putative uncharacterized protein; n=1;
           Vibrio splendidus 12B01|Rep: Putative uncharacterized
           protein - Vibrio splendidus 12B01
          Length = 274

 Score =  101 bits (243), Expect = 2e-20
 Identities = 63/193 (32%), Positives = 101/193 (52%), Gaps = 10/193 (5%)

Query: 61  TIPLSSVTLTAPIHGVDKILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRI 120
           +IPL SV +  P    +K+  +G+N+  H       PPP+   F K  S++I   + +++
Sbjct: 65  SIPLESVEVLLPTKP-EKVFAVGMNFASHLASPADAPPPM---FLKLPSSLILTGEVIQV 120

Query: 121 RTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLLG 180
                + V +E EL VV+GRE S   EE+A Q + G TV  DI+ R WQ      Q+L  
Sbjct: 121 PPKA-RNVHFEGELVVVIGRELSQASEEEAEQAIFGVTVGNDITERSWQGADL--QWLRA 177

Query: 181 KSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMT 240
           K+ D F P+G  ++   +      + ++  +NG + Q  +T+ ++H    ++  +S   T
Sbjct: 178 KASDGFGPVGNTIVRGIDYN---NIELTTRVNGKVVQQENTSFMIHKPRKVVSYLSYYFT 234

Query: 241 LVPGDLILTGTPG 253
           L PGDLI  GTPG
Sbjct: 235 LKPGDLIFMGTPG 247


>UniRef50_Q28QQ6 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=3;
           Proteobacteria|Rep: Fumarylacetoacetate (FAA) hydrolase
           - Jannaschia sp. (strain CCS1)
          Length = 305

 Score =  100 bits (240), Expect = 4e-20
 Identities = 84/291 (28%), Positives = 133/291 (45%), Gaps = 22/291 (7%)

Query: 17  VGYLEGDDIVDINKA---DSSLPTTLLQILRN-GDLEKVKKLKSTKP--ATIPLSSVTLT 70
           V  L+ D ++D+ +A   D     T+  I      L+K + +    P  A I LS     
Sbjct: 15  VARLDDDQVLDLLEASGGDVHFVNTVAMIEAGPAALDKARAVLEDPPTRAVIALSQAEHR 74

Query: 71  APIHGVDKILCI--------GLNYKDHCQEQNLTPPPV----PMVFSKFSSTIIGPDQPV 118
            P+  V    C+        G    +    +    PPV    P+ +     + IG  Q V
Sbjct: 75  VPLRPVQYRDCLVFEQHLINGFKQAEKMTGRPFAIPPVWYEQPIYYKGNRMSFIGHGQTV 134

Query: 119 RIRTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQF- 177
           R     +  +D E+EL +++G+E + +  E A +H+ GYT+  D+SARD Q  +  GQ  
Sbjct: 135 RWPA-YSDYLDLELELAIIIGKEGADIPRETAHEHIWGYTILNDVSARDAQMREMAGQLG 193

Query: 178 -LLGKSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRIS 236
              GK  DT   LGP ++T+DEV     L +  S+NG      ++A +      ++  IS
Sbjct: 194 PAKGKDFDTGNILGPWIVTADEVSHPAVLNMDVSVNGERWGGGTSADMQFDFAQIIAHIS 253

Query: 237 SVMTLVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIGAFDVRIEK 287
           +   L PG++I +GT  G G   +  + L  GD++   IEKIG     I+K
Sbjct: 254 ASERLFPGEVIGSGTV-GTGCGLEIGKRLSDGDMMDLTIEKIGTLTNTIKK 303


>UniRef50_A0JY14 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=2;
           Arthrobacter|Rep: Fumarylacetoacetate (FAA) hydrolase -
           Arthrobacter sp. (strain FB24)
          Length = 277

 Score =  100 bits (240), Expect = 4e-20
 Identities = 61/179 (34%), Positives = 97/179 (54%), Gaps = 13/179 (7%)

Query: 101 PMVFSKFSSTIIGPDQPVRIRTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVA 160
           P  F K +++++GP   + +   V   VD E EL +V+GR+A  +  E+A   V G+T+ 
Sbjct: 102 PQAFHKAATSVVGPGDAIELAPGVGH-VDPEAELTIVIGRKARGLTLENARGAVLGFTIG 160

Query: 161 QDISARDWQKEKNMGQFLLGKSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSS 220
            D++AR+ QK   +  ++  KS DTF P GP ++T  +  A   L +    NG   +++S
Sbjct: 161 NDVTARELQKSDEL--WISAKSQDTFTPAGPWIVTGLDTAA---LSIGIVHNGSELRAAS 215

Query: 221 TAQLVHSIPSLLHRISSVMTLVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIG 279
           +A L   +  +L  ++S MTL PGDL+LTG P            L PGD +T  ++ IG
Sbjct: 216 SADLGWKVDEILVYLTSFMTLHPGDLVLTGFPA-------ESARLHPGDTVTCRVQGIG 267


>UniRef50_Q9LUR3 Cluster: Isomerase-like protein; n=5; rosids|Rep:
           Isomerase-like protein - Arabidopsis thaliana (Mouse-ear
           cress)
          Length = 224

 Score =  100 bits (239), Expect = 5e-20
 Identities = 64/181 (35%), Positives = 95/181 (52%), Gaps = 4/181 (2%)

Query: 78  KILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRIRTDVTKKVDWEVELCVV 137
           KI+ +GLNY  H +E     P  P+VF K +S+ +     + I   +   +  EVEL VV
Sbjct: 15  KIVGVGLNYASHAKELGNALPKDPIVFLKPTSSYLENGGTIEIPHPLDS-LHHEVELAVV 73

Query: 138 VGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQF--LLGKSMDTFCPLGPCVLT 195
           +G++A  V E  A+ ++ GY +A D++AR+ Q           L K  DTF P+   VL 
Sbjct: 74  IGQKARDVPERLAMNYIGGYALALDMTARELQVSAMASGLPCTLAKGQDTFTPISS-VLP 132

Query: 196 SDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPGDLILTGTPGGV 255
              V     L +   ++   +Q   T  ++  +P L+  ISSVMTL  GD+ILTGTP G+
Sbjct: 133 KAMVLDPNNLELWLKVDDETRQKGWTKDMIFKVPYLISYISSVMTLFKGDVILTGTPEGI 192

Query: 256 G 256
           G
Sbjct: 193 G 193


>UniRef50_A1KUG3 Cluster: Putative hydrolase; n=4; Neisseria|Rep:
           Putative hydrolase - Neisseria meningitidis serogroup C
           / serotype 2a (strain ATCC 700532 /FAM18)
          Length = 218

 Score =   99 bits (238), Expect = 6e-20
 Identities = 67/196 (34%), Positives = 102/196 (52%), Gaps = 5/196 (2%)

Query: 64  LSSVTLTAPIHGVDKILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRIRTD 123
           ++SV L      V  I CIG NY  H +E     P  P+VF K S +I+     + +  +
Sbjct: 1   MASVFLEGEAVEVGNIFCIGRNYAAHIEELKNEIPSEPVVFMKPSGSILNSGGTILL-PE 59

Query: 124 VTKKVDWEVELCVVVGREASCVRE-EDALQHVAGYTVAQDISARDWQKE-KNMG-QFLLG 180
            ++ V +E EL ++VG+++  + E ED L  VAGY V  D++ARD Q   K  G  +L  
Sbjct: 60  FSRDVQFECELVLLVGKDSDGMGEGEDILGCVAGYGVGLDLTARDIQCHLKAQGLPWLKA 119

Query: 181 KSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMT 240
           K       +      +D +G   ++  S   NGVLKQ   T  +++ I  +LH++++   
Sbjct: 120 KGFRHSACVSDFA-AADRIGNPEKVLFSLKQNGVLKQRGDTGLMIYPIREILHKLAADYG 178

Query: 241 LVPGDLILTGTPGGVG 256
           L  GDL+ TGTP GVG
Sbjct: 179 LGKGDLVFTGTPSGVG 194


>UniRef50_Q9P7L4 Cluster: Uncharacterized hydrolase C21C3.09c; n=1;
           Schizosaccharomyces pombe|Rep: Uncharacterized hydrolase
           C21C3.09c - Schizosaccharomyces pombe (Fission yeast)
          Length = 221

 Score = 99.5 bits (237), Expect = 9e-20
 Identities = 76/221 (34%), Positives = 114/221 (51%), Gaps = 19/221 (8%)

Query: 78  KILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQP-VRIRTDVTKKVDWEVELCV 136
           K++CIG NY  H +E N   P  P  F K +S I+ P    + I  DV+    +EVEL +
Sbjct: 7   KVVCIGRNYAAHIRELNNPFPTKPFFFLKPTSAIVEPGHGNLIIPPDVS--AHYEVELGL 64

Query: 137 VVGREASCVREEDA---LQHVAGYTVAQDISARDWQKE-KNMG-QFLLGKSMDTFCPLGP 191
           ++       R   +   L  +  Y V  D++AR+ Q E K  G  +   K  DTF P+GP
Sbjct: 65  IMKDRLPARRPVSSNSWLDSIGAYFVGIDMTARNIQNEAKKKGLPWSFAKGYDTFLPVGP 124

Query: 192 CV---LTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPGDLIL 248
            +   L  D     +EL    SLNG + Q  ST+ +++ IP +   I+  M+L PGDL+L
Sbjct: 125 IIPKHLIPDPHNVILEL----SLNGKVVQKDSTSLMLNKIPKIFSSITEAMSLNPGDLVL 180

Query: 249 TGTPGGVGMYRQPPEYLQPGDVLTSEIEKI--GAFDVRIEK 287
           TGTP GVG     P  +    +LT++ ++I    F+++ EK
Sbjct: 181 TGTPKGVGPV--VPGDILSARLLTAQEQEIIPSKFEIKAEK 219


>UniRef50_P53889 Cluster: Uncharacterized hydrolase YNL168C; n=7;
           Saccharomycetales|Rep: Uncharacterized hydrolase YNL168C
           - Saccharomyces cerevisiae (Baker's yeast)
          Length = 259

 Score = 99.1 bits (236), Expect = 1e-19
 Identities = 76/230 (33%), Positives = 115/230 (50%), Gaps = 39/230 (16%)

Query: 78  KILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRIRT-------------DV 124
           KI+CIG NY  H +E N + P  P  F K +S+I+ P     ++T             D 
Sbjct: 11  KIICIGRNYAAHIKELNNSTPKQPFFFLKPTSSIVTPLSSSLVKTTRPANSTFNGLNEDG 70

Query: 125 TK----------KVDWEVELCVVVGREASCV---REEDALQHVAGYTVAQDISARDWQKE 171
           T           KV  E+EL ++V +  S V   + E+    ++G  +A D++AR+ Q E
Sbjct: 71  TNPGPIFIPRGVKVHHEIELALIVSKHLSNVTKMKPEEVYDSISGVALALDLTARNVQDE 130

Query: 172 -KNMG-QFLLGKSMDTFCPLGPCV----LTSDEVGAAVELRVSCSLNGVLKQSSSTAQLV 225
            K  G  + + K  DTF P+   V     +S +       RV CS+NG L+Q   T  ++
Sbjct: 131 AKKKGLPWTISKGFDTFMPISAIVSREKFSSYKSNLQDIFRVKCSVNGQLRQDGGTNLML 190

Query: 226 HSIPSLLHRISSVMTLVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEI 275
           H +  +L  IS++++L PGD+ILTGTP GVG        L+PGD +  E+
Sbjct: 191 HPLHKILQHISTMISLEPGDIILTGTPAGVG-------ELKPGDRVHCEL 233


>UniRef50_Q1I918 Cluster: 4-hydroxyphenylacetate degradation;
           2-hydroxyhepta-2,4-diene-1,7- dioate isomerase; n=8;
           Pseudomonas|Rep: 4-hydroxyphenylacetate degradation;
           2-hydroxyhepta-2,4-diene-1,7- dioate isomerase -
           Pseudomonas entomophila (strain L48)
          Length = 224

 Score = 98.7 bits (235), Expect = 1e-19
 Identities = 66/183 (36%), Positives = 98/183 (53%), Gaps = 11/183 (6%)

Query: 97  PPPVPMVFSKFSSTIIGPDQPVRIRTDVTKKVDWEVELCVVVGREASCVREEDALQHVAG 156
           PP  P++F K  +T     Q V     V K++     L VV+GR+AS V  E+AL+HVAG
Sbjct: 39  PPVKPVLFIKTPNTRNSHGQAVTYPAAV-KRLQPGPALGVVMGRDASRVSAENALEHVAG 97

Query: 157 YTVAQDISARDWQKEKNMGQFLLGKSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLK 216
           YT+  + S  +   +      +  K  D FCPLGP ++ + +V     L +   +NG L+
Sbjct: 98  YTIVNEFSLPE---DSYYRPAVKAKCRDGFCPLGPQLVPAAQVANPDALGIRLWVNGELR 154

Query: 217 QSSSTAQLVHSIPSLLHRISSVMTLVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIE 276
           Q ++TA  V S+  L+  IS  MTL  GD+++TGTP G          + PGD +T EI+
Sbjct: 155 QHNNTANCVRSVAQLIAEISEFMTLHAGDVLITGTPEG-------RIDVLPGDRVTVEID 207

Query: 277 KIG 279
            +G
Sbjct: 208 GLG 210


>UniRef50_A6FIA8 Cluster: Fumarylacetoacetate hydrolase family
           protein; n=1; Moritella sp. PE36|Rep:
           Fumarylacetoacetate hydrolase family protein - Moritella
           sp. PE36
          Length = 231

 Score = 97.9 bits (233), Expect = 3e-19
 Identities = 59/184 (32%), Positives = 101/184 (54%), Gaps = 4/184 (2%)

Query: 76  VDKILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRIRTDVTKKVDWEVELC 135
           V K++CIG NY DH +E     P   ++F K S++++  D+P+ +  D+ +  + E+E+ 
Sbjct: 28  VGKVVCIGRNYLDHIRELGNDVPEQALLFIKPSTSLVALDKPLPLPVDLGECHN-ELEVA 86

Query: 136 VVVGREASCVREEDALQHVAGYTVAQDISARDWQKE-KNMGQ-FLLGKSMDTFCPLGPCV 193
           +++    +        + + G  +  D++ RD Q   K  G  +   K+ D  CP+ P +
Sbjct: 87  LLIKSPITKGTSIVLSELIWGVGLGLDLTLRDLQSSLKGQGHPWERAKAFDNACPVTPFI 146

Query: 194 LTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPGDLILTGTPG 253
             + E G    L  + S+N  L+Q   TA ++ SI SLL  I++  TL+PGD++LTGTP 
Sbjct: 147 PLA-EFGDVNNLDFTLSVNDQLRQQGCTANMMRSIESLLTEITACFTLLPGDIVLTGTPA 205

Query: 254 GVGM 257
           GVG+
Sbjct: 206 GVGV 209


>UniRef50_A2CBF2 Cluster: Putative uncharacterized protein; n=1;
           Prochlorococcus marinus str. MIT 9303|Rep: Putative
           uncharacterized protein - Prochlorococcus marinus
           (strain MIT 9303)
          Length = 237

 Score = 97.5 bits (232), Expect = 3e-19
 Identities = 62/192 (32%), Positives = 104/192 (54%), Gaps = 10/192 (5%)

Query: 101 PMVFSKFSSTIIGPDQPVRIRTDVTKKVDWEVELCVVVGREASCVREED-ALQHVAGYTV 159
           P++ SK +S+I G    V   +   +++DWE EL V +G+E   +  +D A + +  + V
Sbjct: 50  PILSSKATSSI-GTSNSVIPFSVQNREIDWEAELVVEIGKECFALESKDEAHKVIMRWGV 108

Query: 160 AQDISARDWQKEKNMGQFLLGKSMDTFCPLGPCVLTSDEVGAA----VELRVSCSLNGVL 215
             DI+ R WQ+ ++ GQ++ GKS   F PL   +  SD   AA    ++  + C +NG L
Sbjct: 109 GNDITDRWWQR-RDGGQWIRGKSFPGFAPL---IFNSDSFSAARNNELDREIRCIVNGKL 164

Query: 216 KQSSSTAQLVHSIPSLLHRISSVMTLVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEI 275
            Q    ++++ S   ++ +IS  + L+ GDLI  GT  G  +   P  YL+ GD +T+EI
Sbjct: 165 VQHGVLSEMISSPVQIVWQISQCLQLLKGDLIFCGTFPGSALNSNPSTYLEIGDEVTTEI 224

Query: 276 EKIGAFDVRIEK 287
           E +G    ++ K
Sbjct: 225 EGLGKLHNKVVK 236


>UniRef50_Q0TZ11 Cluster: Putative uncharacterized protein; n=1;
           Phaeosphaeria nodorum|Rep: Putative uncharacterized
           protein - Phaeosphaeria nodorum (Septoria nodorum)
          Length = 255

 Score = 96.7 bits (230), Expect = 6e-19
 Identities = 58/183 (31%), Positives = 100/183 (54%), Gaps = 5/183 (2%)

Query: 93  QNLTPPPVPMVFSKFSSTIIGPDQPVRIRTDVTKKV-DWEVELCVVVGREASCVREEDAL 151
           Q LT P  P +++K ++++  P++ + I     + + D+E EL  V   E   V E  A 
Sbjct: 57  QKLTIPSNPPLWTKPAASLAHPNEEIPINDFCARSLPDYEGELVFVTSEECKDVTESQAK 116

Query: 152 QHVAGYTVAQDISARDWQKEKNM-GQFLLGKSMDTFCPLGPCVLTSDEVGAAVELR-VSC 209
            ++ GYT+  D++ R +Q   NM GQF   K+ D F P+ P VL S ++  +V+   ++ 
Sbjct: 117 DYILGYTIGNDLTCRMFQLPGNMSGQFFFAKAFDHFAPIDP-VLISPKLFESVKRNGLTL 175

Query: 210 SLNGVLKQSSSTAQ-LVHSIPSLLHRISSVMTLVPGDLILTGTPGGVGMYRQPPEYLQPG 268
            +NG ++Q +     ++ S   +L  +S   T+  G  ++TGT  GVG +R+P  +LQ G
Sbjct: 176 KVNGEVRQKADLHNDMIFSPERILSHMSQGTTIPAGTAVMTGTCEGVGAFRKPKVFLQQG 235

Query: 269 DVL 271
           DV+
Sbjct: 236 DVV 238


>UniRef50_Q1ATV3 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=3;
           Actinobacteria (class)|Rep: Fumarylacetoacetate (FAA)
           hydrolase - Rubrobacter xylanophilus (strain DSM 9941 /
           NBRC 16129)
          Length = 320

 Score = 95.5 bits (227), Expect = 1e-18
 Identities = 80/292 (27%), Positives = 138/292 (47%), Gaps = 31/292 (10%)

Query: 16  RVGYLEGDDIVDINKADSSLPTTLLQILRNGDLEKVKKLKSTKPATIPLSSVTLTAPIHG 75
           R+G + G++I  + +      T +L +L   D E+  ++  T  A++PL+ V L AP+  
Sbjct: 13  RLGVVSGEEIGPLPEG-----TDVLDLLA-ADPEERDRIARTAEASVPLTGVRLLAPLQ- 65

Query: 76  VDKILCIGLNYKDHCQ-------EQNLTPPP---VPMVFSKFSSTIIGPDQPVRIRTDVT 125
               L   + +++H +       E+   P     +P  +     ++IGP  PV +     
Sbjct: 66  -PPTLRDFVVFEEHVEGITRSVSEEGGVPEAWYEIPTFYFGNPYSVIGPQDPVAVPPGC- 123

Query: 126 KKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLLGKSMDT 185
           + +D+E+E+  ++GR  S +  E+A  H+AGYT+  D SARD Q+ +        K  D 
Sbjct: 124 EALDFELEVAAIIGRAGSNLAPEEARGHIAGYTILNDWSARDLQRHEMQIGLGPAKGKDF 183

Query: 186 FCPLGPCVLTSDEV-----GAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMT 240
              LGP ++TSDE+        + L +   +NG      + A +  S   L+   S    
Sbjct: 184 ANTLGPWIVTSDELEPYRRDGRLHLEMEVFVNGEKLGDDTLANMAWSFEELVAYASRGTW 243

Query: 241 LVPGDLILTGTPGGVGMY-------RQPPEYLQPGDVLTSEIEKIGAFDVRI 285
           + PGD++ +GT G   +        RQ P  L+PGDV+   +E IG  + R+
Sbjct: 244 VRPGDVLGSGTCGSGCLAELWGRVGRQEPPLLEPGDVVRMTVEGIGTIENRV 295


>UniRef50_Q2I760 Cluster: PlaH; n=1; Streptomyces sp. Tu6071|Rep:
           PlaH - Streptomyces sp. Tu6071
          Length = 294

 Score = 95.1 bits (226), Expect = 2e-18
 Identities = 73/199 (36%), Positives = 99/199 (49%), Gaps = 10/199 (5%)

Query: 63  PLSSVTLTAPIHGVDKILCIGLNYKDHCQEQNLTPPPVPMVFS---KFSSTIIGPDQPVR 119
           PLS VTL  P     KI C+ LNY           P  P   S   K  ST++G    V 
Sbjct: 47  PLSEVTLLPPAEPT-KIACVALNYAPQGSPTGPGRPANPAACSVVLKPPSTLVGHGAVVG 105

Query: 120 IRTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISA--RDWQKEKNMGQF 177
                  ++  E EL VV+G     V  E A + VAGYT A D++A  R   +E +    
Sbjct: 106 -HPGEPWELRHEAELAVVIGTACKGVPAERAAEVVAGYTCADDLTAYVRRAPEEPSGHPP 164

Query: 178 LLGKSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISS 237
           +  K  DTF PLGP  LT+D   A V   ++C +NG ++Q   T  L+  +  ++  +S 
Sbjct: 165 VWAKHFDTFTPLGPW-LTTDLDPADVP--ITCRVNGEVRQDGGTRGLLTPVHEIVAVVSR 221

Query: 238 VMTLVPGDLILTGTPGGVG 256
            M+L+PGD+ILTGTP G G
Sbjct: 222 HMSLLPGDVILTGTPTGSG 240


>UniRef50_Q89D60 Cluster: Blr7583 protein; n=1; Bradyrhizobium
           japonicum|Rep: Blr7583 protein - Bradyrhizobium
           japonicum
          Length = 261

 Score = 94.3 bits (224), Expect = 3e-18
 Identities = 69/225 (30%), Positives = 110/225 (48%), Gaps = 19/225 (8%)

Query: 61  TIPLSSVTLTAPIHGVDKILCIGLNYKDHCQE----QNLTP--PPVPMVFSKFSSTIIGP 114
           T+PL  V +  P+       C+GLNY  H +E    +   P  P  P +  +  + +I  
Sbjct: 39  TLPLGEVKIELPLIP-RTFYCVGLNYLKHLKEAADKRGEVPAVPDRPEIGYRAQNALIAH 97

Query: 115 DQPVRIRTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNM 174
           D+ V I +  T K+ +E EL VV+G++   + +++A+  V GYT+  D+S R WQK    
Sbjct: 98  DEEVVIPSFATDKIHYEGELVVVIGKKVKHLTKQNAMDCVFGYTIGNDVSERSWQKADR- 156

Query: 175 GQFLLGKSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHR 234
                 K+ DTF P+GP + T   + A +E  V   +NG       T  ++  +   L  
Sbjct: 157 -SLWRSKNADTFKPMGPWIETEANL-ARMETVV--RVNGKETNRFYTNDMIFGVVPFLVE 212

Query: 235 ISSVMTLVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIG 279
           ++   TL PGD+I  GT G        P+ ++ GDV+  +I  IG
Sbjct: 213 LTKYFTLWPGDVIWMGTDGA------SPD-IKHGDVVEIDITGIG 250


>UniRef50_Q0VTE8 Cluster: Fumarylacetoacetate hydrolase family
           protein; n=1; Alcanivorax borkumensis SK2|Rep:
           Fumarylacetoacetate hydrolase family protein -
           Alcanivorax borkumensis (strain SK2 / ATCC 700651 / DSM
           11573)
          Length = 233

 Score = 94.3 bits (224), Expect = 3e-18
 Identities = 59/187 (31%), Positives = 96/187 (51%), Gaps = 11/187 (5%)

Query: 76  VDKILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRIRTDVTKKVDWEVELC 135
           V K++C+G NY DH +E     P  P++F K ++ +    +P+ +  +    V  EVE+ 
Sbjct: 29  VGKVVCVGRNYADHAKELGNETPDAPILFMKPATALTSLHEPL-VLPEGQGPVHHEVEMV 87

Query: 136 VVVGREASCVREEDALQHV----AGYTVAQDISARDWQKE-KNMGQ-FLLGKSMDTFCPL 189
           V++G+    +R+E  L HV    A Y +  D++ R+ Q + K  G  +   K+ D   P+
Sbjct: 88  VLIGKR---IRKETRLDHVRFSVAAYGIGLDLTLREVQNQLKEKGHPWERAKAFDGAAPV 144

Query: 190 GPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPGDLILT 249
              +  +  +    +L V+  LN  +KQ   T Q++     LL  IS   TL PGD++ T
Sbjct: 145 SGFI-DARGISVRQDLGVTLELNDAVKQHGHTGQMLFPTFELLSEISQTFTLEPGDVVFT 203

Query: 250 GTPGGVG 256
           GTP GVG
Sbjct: 204 GTPAGVG 210


>UniRef50_A0QS23 Cluster: 5-carboxymethyl-2-hydroxymuconate
           delta-isomerase; n=1; Mycobacterium smegmatis str. MC2
           155|Rep: 5-carboxymethyl-2-hydroxymuconate
           delta-isomerase - Mycobacterium smegmatis (strain ATCC
           700084 / mc(2)155)
          Length = 206

 Score = 93.9 bits (223), Expect = 4e-18
 Identities = 60/184 (32%), Positives = 92/184 (50%), Gaps = 3/184 (1%)

Query: 97  PPPVPMVFSKFSSTIIGPDQPVRIRTDVTKKVDWEVELCVVVGREA-SCVREEDALQHVA 155
           PP VP +F K + ++IGP +P+++   V  +V  E EL +V+G +    V  E A   +A
Sbjct: 18  PPDVPQLFVKNTHSVIGPGEPLQLTGSVATRVVAEGELAIVIGDQCRDLVTAEQARTVIA 77

Query: 156 GYTVAQDISARDWQKEKNMGQFLLGKSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVL 215
           GY VA D++ARD Q+  +   +  GK +D FCPLG  ++   ++    ++ +   ++  L
Sbjct: 78  GYWVANDVTARDLQEVDD--HWSRGKGLDGFCPLGVEMVAPRDMPTWKDVMIRTWVDDEL 135

Query: 216 KQSSSTAQLVHSIPSLLHRISSVMTLVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEI 275
            Q  S A        L+   S   TL PGD+ L GTP       +    L+PG     EI
Sbjct: 136 VQDESVAAAYVGPEELVCWASQQFTLHPGDIFLLGTPAYRPAGDESRAVLKPGHTARVEI 195

Query: 276 EKIG 279
             IG
Sbjct: 196 TGIG 199


>UniRef50_Q2W396 Cluster: 2-keto-4-pentenoate
           hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase;
           n=5; Alphaproteobacteria|Rep: 2-keto-4-pentenoate
           hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase -
           Magnetospirillum magneticum (strain AMB-1 / ATCC 700264)
          Length = 265

 Score = 93.5 bits (222), Expect = 6e-18
 Identities = 68/230 (29%), Positives = 112/230 (48%), Gaps = 20/230 (8%)

Query: 62  IPLSSVTLTAPIHGVDKILCIGLNYKDHCQEQNLTPP-PVPMVFSKFSSTII--GPDQPV 118
           +P  +V   A ++ V ++ C+G NY  H +E    P    P  F+K +  ++  G D P 
Sbjct: 46  LPAVAVKGEAALYPVRRVFCVGRNYAGHAREMGGDPNREAPFYFTKPADALVPGGGDIPY 105

Query: 119 RIRTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQ-KEKNMGQ- 176
                 T  +  E+EL V + R       ++A   + GY V  D++ RD Q   ++ G+ 
Sbjct: 106 ---PPGTANLHHEIELVVALSRSVYKCTPDEASTAIFGYAVGLDMTRRDLQFAARDKGRP 162

Query: 177 FLLGKSMDTFCPLGPCVLT-SDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRI 235
           + LGK+ +   P+ P V   + ++  ++ L V    NG ++QS    +++ S+P ++  +
Sbjct: 163 WCLGKAFEFSAPISPLVRADAPKLAGSITLEV----NGQIRQSGDLNEMIWSVPEVIAHL 218

Query: 236 SSVMTLVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIGAFDVRI 285
           S    L  GDLI TGTP GVG        +  GDVL   IE +G  +V I
Sbjct: 219 SQYYHLGAGDLIFTGTPEGVGP-------VVAGDVLRGAIEGVGELEVHI 261


>UniRef50_Q1GJL0 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=8;
           Proteobacteria|Rep: Fumarylacetoacetate (FAA) hydrolase
           - Silicibacter sp. (strain TM1040)
          Length = 256

 Score = 93.1 bits (221), Expect = 7e-18
 Identities = 65/202 (32%), Positives = 100/202 (49%), Gaps = 10/202 (4%)

Query: 58  KPATIPLSSVTLTAPIHGVDKILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQP 117
           +PA +P++  T   P+    ++ CIG NY  H  E    P   P  F  F  T    D  
Sbjct: 39  QPA-LPIAESTALFPVR---RVYCIGRNYAAHAVEMGHDPDREPPFF--FQKTPDSLDAS 92

Query: 118 VRIRTDV-TKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQK-EKNMG 175
            R    V ++ V  E EL V +G+    + E+ AL HV GY +A D++ RD Q   K  G
Sbjct: 93  GRFPYPVMSEDVHHEAELLVALGKGGENISEDAALDHVWGYGLALDMTRRDLQGIAKKAG 152

Query: 176 Q-FLLGKSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHR 234
           + + +GKS +   P+ P +  +  +G      ++ ++NG  +Q     Q++  IP ++  
Sbjct: 153 RPWEIGKSFEHAAPVAP-LTPATTIGHPDAGVMTLTVNGTPRQQGDLNQMIWKIPEMIAH 211

Query: 235 ISSVMTLVPGDLILTGTPGGVG 256
           +S    L  GD+ILTGTP GVG
Sbjct: 212 LSQYYRLAAGDVILTGTPAGVG 233


>UniRef50_A4F0I3 Cluster: Fumarylacetoacetate hydrolase family
           protein; n=1; Roseobacter sp. SK209-2-6|Rep:
           Fumarylacetoacetate hydrolase family protein -
           Roseobacter sp. SK209-2-6
          Length = 231

 Score = 93.1 bits (221), Expect = 7e-18
 Identities = 63/197 (31%), Positives = 96/197 (48%), Gaps = 11/197 (5%)

Query: 69  LTAPIHG------VDKILCIGLNYKDHCQEQNL-TPPPVPMVFSKFSSTIIGPDQPVRIR 121
           LT P+HG      V++I C+G NY  H  E  +      P  F+K ++  +     V   
Sbjct: 12  LTIPVHGETAEFPVNRIFCVGRNYAAHAAEMGVEVDREAPFYFTKSAANAVLTGCEVPYP 71

Query: 122 TDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQ--FLL 179
              T+   +E+EL + +G  A     E+A   + GY  A D++ RD Q  +   Q  + L
Sbjct: 72  PG-TENFHYEMELALAIGASAFRASPEEARAAIYGYGCALDMTRRDLQIRERQKQRPWDL 130

Query: 180 GKSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVM 239
           GK ++    L P    SD  G   E  +   L+G +KQ ++ A+L+ S   ++  +S   
Sbjct: 131 GKDLEQGTVLAPFTKASDW-GPVAEQPIWLELDGEIKQDATLAELIWSCEEIICHLSCYY 189

Query: 240 TLVPGDLILTGTPGGVG 256
            L PGD+ILTGTP GVG
Sbjct: 190 HLQPGDIILTGTPAGVG 206


>UniRef50_Q6N496 Cluster: Possible isomerase/decarboxylase; n=4;
           Alphaproteobacteria|Rep: Possible
           isomerase/decarboxylase - Rhodopseudomonas palustris
          Length = 329

 Score = 92.3 bits (219), Expect = 1e-17
 Identities = 51/162 (31%), Positives = 88/162 (54%), Gaps = 3/162 (1%)

Query: 128 VDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQF--LLGKSMDT 185
           +D+E+E  ++  R+ + +    A  H+ GYT+  D SARD Q+ +  G+     GKS D 
Sbjct: 166 MDYELEFGIITKRKGANISAAQAKNHIFGYTIFNDFSARDAQRIEMEGRLGPAKGKSFDG 225

Query: 186 FCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPGD 245
              +GP ++T DE+G    L +   +NG ++    T  ++ S   ++  +S   TL+PG+
Sbjct: 226 GNVIGPWIVTPDEIGDPYRLNMEARVNGEVRSRGVTEGMLFSFEEIIAHVSRDETLMPGE 285

Query: 246 LILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIGAFDVRIEK 287
            I +GT G  G   +   +L+ GDV+  E+EKIG    ++E+
Sbjct: 286 FIGSGTVGN-GCGLELGWFLEHGDVIELEVEKIGIPKNKVER 326


>UniRef50_A1SFW5 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=1;
           Nocardioides sp. JS614|Rep: Fumarylacetoacetate (FAA)
           hydrolase - Nocardioides sp. (strain BAA-499 / JS614)
          Length = 280

 Score = 92.3 bits (219), Expect = 1e-17
 Identities = 59/184 (32%), Positives = 97/184 (52%), Gaps = 9/184 (4%)

Query: 100 VPMVFSKFSSTIIGPDQPVRIRTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTV 159
           +P  +     T+IGP+  +      T+++D E+EL  V+GR    + E++AL HV GYT+
Sbjct: 91  LPAYYKGLPDTVIGPEDEIPWPA-YTQRLDHELELAAVIGRPGKDITEDNALDHVFGYTI 149

Query: 160 AQDISARDWQKEK---NMGQFLLGKSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLK 216
             D+SARD Q  +    MG     K  D    LGPC++T+DEV    ++ +   +NG   
Sbjct: 150 WNDLSARDVQAGELPVGMGPG-KAKDWDGSNVLGPCIVTADEVDPH-DIELEVRVNGERW 207

Query: 217 QSSSTAQLVHSIPSLLHRISSVMTLVPGDLILTGT-PGGVGMYRQPPEYLQPGDVLTSEI 275
             ++T  + H+  S++   S  + L PG+++ +GT  GG G+  +   +L P D +  E 
Sbjct: 208 GGANTRDMHHTFESMIVYASQALMLRPGEVLGSGTATGGSGV--ELGRWLAPADTVEMEA 265

Query: 276 EKIG 279
             IG
Sbjct: 266 SGIG 269


>UniRef50_Q5GXD7 Cluster: Fumarylacetoacetate hydrolase; n=8;
           Xanthomonadaceae|Rep: Fumarylacetoacetate hydrolase -
           Xanthomonas oryzae pv. oryzae
          Length = 290

 Score = 91.1 bits (216), Expect = 3e-17
 Identities = 67/214 (31%), Positives = 103/214 (48%), Gaps = 20/214 (9%)

Query: 76  VDKILCIGLNYKDHCQEQNLTPPPV------PMVFSKFSSTIIGPDQPVRIRTDVTKKVD 129
           V +I C+G N+ DH +E   + P        P  F K +  I+            TK++ 
Sbjct: 77  VHRIYCVGRNFADHAREMGASAPASKAERGQPTFFMKPADAIVVGHGDQIPYPPGTKELH 136

Query: 130 WEVELCVVVGREASC--VREEDALQHVAGYTVAQDISARDWQ---KEKNMGQFLLGKSMD 184
            EVEL V +G +A    +  E A + + GY V  D++ RD Q   K K +  + + K  D
Sbjct: 137 HEVELVVALGSDAPAGELPVEQAERLIYGYGVGLDLTRRDLQAAAKAKGL-PWDIAKGFD 195

Query: 185 TFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPG 244
              P+   V  + EVG    L +S  +NG ++Q S   Q++ ++P +LH +S +  L  G
Sbjct: 196 HSAPISELV-HAGEVGVLEALNLSLEVNGQVRQQSLLDQMIWNVPEILHALSKLYALRAG 254

Query: 245 DLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKI 278
           DLI  GTP GVG        L PGD  ++ +E +
Sbjct: 255 DLIFMGTPAGVGP-------LLPGDQFSARLENV 281


>UniRef50_Q1QDY9 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=2;
           Psychrobacter|Rep: Fumarylacetoacetate (FAA) hydrolase -
           Psychrobacter cryohalolentis (strain K5)
          Length = 238

 Score = 91.1 bits (216), Expect = 3e-17
 Identities = 61/203 (30%), Positives = 96/203 (47%), Gaps = 11/203 (5%)

Query: 76  VDKILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQP-VRIRTDVTKKVDWEVEL 134
           + K++C+G NY +H +E     P  P++F K +S+++      VR    +     +E EL
Sbjct: 34  IGKVICVGRNYAEHARELGNEIPKSPILFMKPASSVVSVHNDIVRPNPALYGDTHYEAEL 93

Query: 135 CVVVGREASCVREEDALQHVAGYTVAQDISARDWQ-KEKNMGQ-FLLGKSMDTFCPLGPC 192
           C+ +  + S    E A Q + G T+  D++ RD Q K K  G  +   K  D  C L   
Sbjct: 94  CIQLAADLSAATIEQAKQAIGGVTLGLDLTLRDLQSKLKEKGHPWERAKCFDGACVLADW 153

Query: 193 VLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPGDLILTGTP 252
           +      G    +     +N  LKQ   +A ++  +  LL  IS   +L  GD+I+TGTP
Sbjct: 154 I-DPQAFGDFCHVEYQLYINDELKQDGDSALMLFPVYELLAEISHAFSLQAGDVIMTGTP 212

Query: 253 GGVGMYRQPPEYLQPGDVLTSEI 275
            GVG+       LQ  D LT ++
Sbjct: 213 SGVGV-------LQAADTLTFKL 228


>UniRef50_A6W055 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate
           decarboxylase; n=1; Marinomonas sp. MWYL1|Rep:
           5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase -
           Marinomonas sp. MWYL1
          Length = 245

 Score = 91.1 bits (216), Expect = 3e-17
 Identities = 56/189 (29%), Positives = 98/189 (51%), Gaps = 9/189 (4%)

Query: 91  QEQNLTPPPVPMVFSKFSSTIIGPDQPVRIRTDVTKKVDWEVELCVVVGREASCVREEDA 150
           ++ ++ PP  P++  K  +T IG  + +++ +D    V     L +V+G++ + V   +A
Sbjct: 57  EKPHVQPPKTPVLHIKTDNTHIGYGKSIKLPSD-KGAVFAGPSLGIVIGKKTTRVDASNA 115

Query: 151 LQHVAGYTVAQDISARDWQKEKNMGQFLLGKSMDTFCPLGPCVLTSDEVGAAVELRVSCS 210
           L  VAG+TV  ++S  +    +     +  K  DTFCP+GP  +    V    +L +   
Sbjct: 116 LDCVAGFTVVNEVSLAETSFYRPA---VKAKCRDTFCPIGPWSVDKSAVSTPNKLSIKTF 172

Query: 211 LNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPGDLILTGTPGGVGMYRQPPEYLQPGDV 270
           +N  L   ++T QL++S+  ++  ISS MTL  GD+I+ GTP      R     + PGD 
Sbjct: 173 INDALVHETNTDQLIYSVEEIVSYISSFMTLEAGDIIIAGTP-----ERTADLAINPGDS 227

Query: 271 LTSEIEKIG 279
           +  +IE +G
Sbjct: 228 VMIDIEGVG 236


>UniRef50_Q7NUB2 Cluster: Probable isomerase; n=3;
           Betaproteobacteria|Rep: Probable isomerase -
           Chromobacterium violaceum
          Length = 216

 Score = 90.6 bits (215), Expect = 4e-17
 Identities = 67/197 (34%), Positives = 92/197 (46%), Gaps = 10/197 (5%)

Query: 64  LSSVTLTAPIHGVDKILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRIRTD 123
           +SSV L      V  I CIG NY  H  E        P+VF K +S ++    P+R+  +
Sbjct: 1   MSSVKLGLHAIRVGNIFCIGRNYAAHAAELGNKVEDEPLVFLKPTSALLDESSPIRL-PE 59

Query: 124 VTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKE-KNMGQ-FLLGK 181
            +  V  E EL  ++G+    +  E AL HVAGY +  D++ARD Q E K  GQ +   K
Sbjct: 60  YSGDVHHECELVALIGKGGDDIPPEKALDHVAGYGIGLDLTARDAQAEAKRKGQPWTKAK 119

Query: 182 SM-DTFC--PLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSV 238
                 C   L P     D      ELRV    NG L+Q      ++ ++   +  +S +
Sbjct: 120 GFRGAACVSTLVPAARVEDPQRLKFELRV----NGQLRQRGDAGLMLFTLAEQISYLSRL 175

Query: 239 MTLVPGDLILTGTPGGV 255
             L  GDLI TGTP GV
Sbjct: 176 YGLSDGDLIFTGTPEGV 192


>UniRef50_O86346 Cluster: POSSIBLE BIFUNCTIONAL ENZYME:
           2-HYDROXYHEPTA-2,4-DIENE-1,7-DIOATE ISOMERASE (HHDD
           ISOMERASE) + CYCLASE/DEHYDRASE; n=9; Mycobacterium|Rep:
           POSSIBLE BIFUNCTIONAL ENZYME:
           2-HYDROXYHEPTA-2,4-DIENE-1,7-DIOATE ISOMERASE (HHDD
           ISOMERASE) + CYCLASE/DEHYDRASE - Mycobacterium
           tuberculosis
          Length = 644

 Score = 89.4 bits (212), Expect = 9e-17
 Identities = 86/285 (30%), Positives = 132/285 (46%), Gaps = 25/285 (8%)

Query: 16  RVGYLEGDDIVDINKADSSLPTTLLQILRNGDLEKVKKLKSTKPATIPLSSVTLTAPIHG 75
           R G L GD I  +   D SL   L+    +G     ++   +  A + L  VTL API  
Sbjct: 13  RTGVLSGDAIYAM-PPDVSL-LDLVGRGADGLRTAGERAVRSPAAVVALDEVTLAAPIPR 70

Query: 76  VDKI---LCIGLNYKDHCQEQNL-------TPPPVPMVFSKFSSTIIGPDQPVRIRTDVT 125
              I   LC  L++  +CQE          T   +P  +    ST++GP           
Sbjct: 71  PPSIRDSLCF-LDHMRNCQEAMGGGRVLMDTWYRIPAFYFACPSTVLGPYDDAPTAPGSA 129

Query: 126 KKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLLGKSMDT 185
            + D+E+E+  V+G     +  E A + + GYT+  D SARD Q  +   +    K  D+
Sbjct: 130 WQ-DFELEIAAVIGTSGKDLTVEQAERSIIGYTIFNDWSARDLQMLEGQLRIGQAKGKDS 188

Query: 186 FCPLGPCVLTSDEV-----GAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMT 240
              LGP ++T DE+     G  + LRV   +NG +  S STAQ+  S   ++   S  +T
Sbjct: 189 GITLGPYLVTPDELEPYCRGGKLSLRVIALVNGTVIGSGSTAQMDWSFGEVIAYASRGVT 248

Query: 241 LVPGDLILTGTPGGVGM--YRQPPE----YLQPGDVLTSEIEKIG 279
           L PGD+  +GT     +  + +PPE    +L  GDV+T ++E +G
Sbjct: 249 LTPGDVFGSGTVPTCTLVEHLRPPESFPGWLHDGDVVTLQVEGLG 293


>UniRef50_A6D592 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=1;
           Vibrio shilonii AK1|Rep: Fumarylacetoacetate (FAA)
           hydrolase - Vibrio shilonii AK1
          Length = 264

 Score = 89.4 bits (212), Expect = 9e-17
 Identities = 64/226 (28%), Positives = 101/226 (44%), Gaps = 20/226 (8%)

Query: 62  IPLSSVTLTAPI-HGVDKILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRI 120
           I     TL API HG   +  +GLN++ H        P +   F    +  +        
Sbjct: 58  ITADEATLLAPITHG--SVYAVGLNFRSHAGNSGAAKPEI--FFKSIDAVRLSGALSF-- 111

Query: 121 RTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLLG 180
             D    V +E EL +V+G+       ++AL  V GY    D++ R WQ +    Q+   
Sbjct: 112 -PDEANNVHFEGELVIVIGKTCHDTSNQNALSCVFGYLAGNDLTERSWQGQDL--QWWRA 168

Query: 181 KSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMT 240
           K    F P+   + T+ ++G      +   LNG + Q  + A ++H++P+++  IS  +T
Sbjct: 169 KGATGFGPVSNFITTNVDIG---NQEIVTRLNGKIMQQETLANMIHNVPTIVSYISKYIT 225

Query: 241 LVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIGAFDVRIE 286
           L PGD+I  GTPG           L+ GD ++  IE IG     IE
Sbjct: 226 LRPGDMIFAGTPGRT-------RALRSGDNVSVSIEGIGQVSNTIE 264


>UniRef50_A1VKI1 Cluster: Fumarylacetoacetate (FAA) hydrolase
           precursor; n=4; Proteobacteria|Rep: Fumarylacetoacetate
           (FAA) hydrolase precursor - Polaromonas
           naphthalenivorans (strain CJ2)
          Length = 245

 Score = 89.0 bits (211), Expect = 1e-16
 Identities = 66/230 (28%), Positives = 107/230 (46%), Gaps = 17/230 (7%)

Query: 59  PATIPLSSVTLTAPIHGVDKILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPV 118
           PAT+ ++  T   P   V ++ CIG NY+    +    P  +P  F K ++ ++     V
Sbjct: 14  PATVAVAGSTAVFP---VGRVFCIGRNYR--WSQDEAMPQEMPAWFMKPANAVVHA-HGV 67

Query: 119 RIRTDVTKKVDWEVELCVVVGREASCVREEDAL-QHVAGYTVAQDISARDWQKEKNM--G 175
                 T     E+EL V +GR    +        H+ GY    D++ RD Q++     G
Sbjct: 68  LPYPPATGDFCHEIELVVAIGRGGRDIAPAQVEPHHIWGYAAGLDLTRRDLQQQAKRAGG 127

Query: 176 QFLLGKSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRI 235
            +   K+ D   P  P V  +   G   +  V  ++NG+ +Q +  + L+  +  L+  +
Sbjct: 128 PWEAAKAFDHSAPCTPLVPAA-ACGHPRQGAVWLTVNGIERQRADVSGLLWPVAELVAML 186

Query: 236 SSVMTLVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIGAFDVRI 285
           S  +TL+PGDLI TGTP GVG        LQPGDV+   +  +G F + +
Sbjct: 187 SRSVTLMPGDLIYTGTPAGVGP-------LQPGDVVQGGVAGVGQFSMTV 229


>UniRef50_Q5P741 Cluster: Fumarylpyruvate hydrolase; n=14;
           Proteobacteria|Rep: Fumarylpyruvate hydrolase - Azoarcus
           sp. (strain EbN1) (Aromatoleum aromaticum (strain EbN1))
          Length = 236

 Score = 87.8 bits (208), Expect = 3e-16
 Identities = 67/215 (31%), Positives = 102/215 (47%), Gaps = 14/215 (6%)

Query: 76  VDKILCIGLNYKDHCQEQNLTPPPV---PMVFSKFSSTIIGPDQPVRIRTDVTKKVDWEV 132
           ++++  +G NY  H  E           P  F+K  ST+      V      TK   +E+
Sbjct: 27  INRLFFVGRNYYAHSVEMGNPVDKATSRPFYFTKAPSTLTESGATVAYPPG-TKNFHYEM 85

Query: 133 ELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQK-EKNMGQ-FLLGKSMDTFCPLG 190
           EL V +G     V E DA + + GY    D++ RD Q   +  G+ + LGK ++    + 
Sbjct: 86  ELVVAIGAPGFRVAEADAEKLIYGYACGLDMTRRDLQLVAREAGRPWDLGKDVEQ-SSVA 144

Query: 191 PCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPGDLILTG 250
             ++   E+G   +  ++  +NG  KQSS  + L+ SIP ++  +S    L PGDLI TG
Sbjct: 145 SEIVPKGELGVVSQGALTLVVNGQTKQSSDVSLLIWSIPEIIADLSQFYHLQPGDLIYTG 204

Query: 251 TPGGVGMYRQPPEYLQPGDVLTSEIEKIGAFDVRI 285
           TP GVG        + PGD L+  IE IG   + I
Sbjct: 205 TPEGVGA-------VNPGDRLSGRIEGIGEISLLI 232


>UniRef50_Q3INL8 Cluster: Probable
           2-hydroxyhepta-2,4-diene-1,7-dioate isomerase 2;
           probable 5- oxopent-3-ene-1,2,5-tricarboxylate
           decarboxylase 2; n=1; Natronomonas pharaonis DSM
           2160|Rep: Probable 2-hydroxyhepta-2,4-diene-1,7-dioate
           isomerase 2; probable 5-
           oxopent-3-ene-1,2,5-tricarboxylate decarboxylase 2 -
           Natronomonas pharaonis (strain DSM 2160 / ATCC 35678)
          Length = 319

 Score = 87.8 bits (208), Expect = 3e-16
 Identities = 57/223 (25%), Positives = 115/223 (51%), Gaps = 13/223 (5%)

Query: 67  VTLTAPIHGVDKILCIGLNYKDHCQEQNLTPPP-----VPMVFSKFSSTIIGPDQPVRIR 121
           V+L AP+   + +    + +++H +      PP     +P+ +   + +++ P + V   
Sbjct: 99  VSLLAPVPRPNSLRDF-MVFEEHVRNALGEEPPDAWYEMPVYYKSTADSVVAPGETVEWP 157

Query: 122 TDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLLGK 181
              +  +D+E+EL  V+G+E   +  E A +++AGYT+  D SARD Q E+   +    K
Sbjct: 158 A-YSSLMDYELELAAVIGKEGRDIPAEAADEYIAGYTIFNDFSARDIQGEEMQARLGPAK 216

Query: 182 SMDTFCPLGPCVLTSDEVG-AAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMT 240
             D     GP ++T+D+      E+R   ++NG +    +  ++ H+   ++  +S   T
Sbjct: 217 GKDFANAFGPYLVTADDFDPETAEMR--ATVNGEVWSEGTPGEMYHTFADIVAHVSQSET 274

Query: 241 LVPGDLILTGTPG-GVGMYRQPPEYLQPGDVLTSEIEKIGAFD 282
           L PGD++ +GT G G G+  +  ++L+ GD ++  ++ IG  +
Sbjct: 275 LYPGDVLGSGTVGEGCGL--ELGQFLESGDTVSLFVDGIGTLE 315


>UniRef50_A5VDV9 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=1;
           Sphingomonas wittichii RW1|Rep: Fumarylacetoacetate
           (FAA) hydrolase - Sphingomonas wittichii RW1
          Length = 317

 Score = 87.0 bits (206), Expect = 5e-16
 Identities = 54/166 (32%), Positives = 81/166 (48%), Gaps = 5/166 (3%)

Query: 125 TKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFL--LGKS 182
           T  +D+E+E   +VG+    +    A  H+ GYT+  D+SARD Q     GQ     GK 
Sbjct: 149 TDWMDFELEWACIVGKGGRNISPAQARAHIFGYTIFNDLSARDVQLAVMAGQIGPGAGKD 208

Query: 183 MDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLV 242
            D   P+GPC++T+D +     L ++ S+NG      STA + HS    +  +S    L 
Sbjct: 209 FDNSNPIGPCIVTADAIPDPYALAMTASVNGEQWSRGSTASMHHSFEDAVVMLSRDRQLH 268

Query: 243 PGDLILTGTP-GGVGMYRQPPEYLQPGDVLTSEIEKIGAFDVRIEK 287
            G++I +GT   G G   Q    L PGDV+   +E IG     + +
Sbjct: 269 AGEIIASGTVLTGCGFELQ--RRLSPGDVVELYVEAIGTLTTTVRR 312


>UniRef50_A5VE51 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate
           decarboxylase; n=1; Sphingomonas wittichii RW1|Rep:
           5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase -
           Sphingomonas wittichii RW1
          Length = 276

 Score = 86.6 bits (205), Expect = 6e-16
 Identities = 54/176 (30%), Positives = 84/176 (47%), Gaps = 8/176 (4%)

Query: 78  KILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRIRTDVTKKVDWEVELCVV 137
           K + IG+NY+   +   +  P  P+V+ +  + IIG    + +  D    V  E EL  V
Sbjct: 76  KYVGIGINYRATAEALGMAMPEEPVVYVRPPNCIIGDGDRIVLPAD--GDVVCEGELAAV 133

Query: 138 VGREASCVREEDALQHVAGYTVAQDI-SARDWQKEKNMGQFLLGKSMDTFCPLGPCVLTS 196
           +GR    + E D   HV GYT+  D+     + K+K  G   L K  D F PLGPC+ T 
Sbjct: 134 IGRRGRDIAEGDVAAHVIGYTLTNDLMDVARFHKDK--GNPSLAKGRDGFAPLGPCIATG 191

Query: 197 DEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPGDLILTGTP 252
            ++  A    ++  +NG   Q+     ++  +   +  IS  MTL PGD++  G P
Sbjct: 192 LDLATA---ELATFVNGARVQAGFARDMLFGVERCVSHISRFMTLEPGDVVALGCP 244


>UniRef50_Q4WH18 Cluster: Fumarylacetoacetate hydrolase family
           protein; n=1; Aspergillus fumigatus|Rep:
           Fumarylacetoacetate hydrolase family protein -
           Aspergillus fumigatus (Sartorya fumigata)
          Length = 249

 Score = 86.2 bits (204), Expect = 9e-16
 Identities = 52/157 (33%), Positives = 84/157 (53%), Gaps = 5/157 (3%)

Query: 133 ELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQ-KEKNMGQFLLGKSMDTFCPLGP 191
           ELC V  RE   +  E+A   + GYT+  D+S R +Q  E++ GQF   K+ D F P+GP
Sbjct: 84  ELCFVTSRECRDLSIEEAPSCILGYTIGNDLSCRFFQLPEQSGGQFFYAKAFDRFAPVGP 143

Query: 192 CVLTSDEVGAAVE--LRVSCSLNGVLKQSSS-TAQLVHSIPSLLHRISSVMTLVPGDLIL 248
            VL    V    E   R+   +NG +KQ S  +  ++++   +L  +S   T+    +++
Sbjct: 144 -VLVHPSVWHKAEKTARLVTRVNGHVKQDSHLSTDMINTPARILSWMSQGTTIPAYTILM 202

Query: 249 TGTPGGVGMYRQPPEYLQPGDVLTSEIEKIGAFDVRI 285
           TGTP GVG ++ P ++L+  D +  EI  +G    R+
Sbjct: 203 TGTPAGVGAFQTPRQFLKDKDSVDVEITGLGVLQNRV 239



 Score = 35.5 bits (78), Expect = 1.6
 Identities = 22/63 (34%), Positives = 32/63 (50%), Gaps = 3/63 (4%)

Query: 32 DSSLPTTLLQILRNGDLEKVKKLKSTKPATIPLSSVTLTAPIHGVDKILCIGLNYKDHCQ 91
          DS+ P T  QI      E +K+ K+     I  + +    P+H +  I C+GLNYK H +
Sbjct: 23 DSTEPLTGAQINAYRSFEDLKERKNGVIRAI--AKLLPPVPVHDLP-IYCVGLNYKSHAK 79

Query: 92 EQN 94
          E N
Sbjct: 80 EAN 82


>UniRef50_A4YZ43 Cluster: Putative Fumarylacetoacetate hydrolase
           family protein; n=3; Proteobacteria|Rep: Putative
           Fumarylacetoacetate hydrolase family protein -
           Bradyrhizobium sp. (strain ORS278)
          Length = 264

 Score = 85.4 bits (202), Expect = 1e-15
 Identities = 70/243 (28%), Positives = 111/243 (45%), Gaps = 23/243 (9%)

Query: 52  KKLKSTKPATIPLSSVTLTAPIHGVDKILCIGLNYKDHCQEQNLTPP-PVPMVFSKFSST 110
           K + +    TIP++      P+    +I CIG NY  H  E+   P    P  F K +  
Sbjct: 35  KPIFAVAATTIPIAGEQGVFPVR---RIYCIGRNYAAHAIERGSDPNREPPFFFQKPTDA 91

Query: 111 I----IGP--DQPVRIRTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDIS 164
           I    +G   D P      +TK    EVEL   +    + +  E AL HV GY +  D++
Sbjct: 92  IQNVAVGEVADHPY---PSLTKNYHHEVELVAALKSGGTNIPVESALDHVYGYALGLDMT 148

Query: 165 ARDWQK--EKNMGQFLLGKSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTA 222
            RD Q         + +GKS D    +GP    S+ VG   +  +S ++NG ++QSS   
Sbjct: 149 RRDLQNGMAAEKKPWEIGKSFDHAAVIGPIHPVSN-VGHFTKGAISLAVNGTVRQSSDLT 207

Query: 223 QLVHSIPSLLHRISSVMTLVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIGAFD 282
           +++ S+   + ++S    L  GD+I +GTP  VG        +  GDVL  ++E +    
Sbjct: 208 KMIWSVAEQIAKLSEAFELKAGDIIYSGTPENVGP-------VVKGDVLLCKLEGLPDMS 260

Query: 283 VRI 285
           ++I
Sbjct: 261 IKI 263


>UniRef50_Q4WX41 Cluster: Fumarylacetoacetate hydrolase family
           protein; n=15; Ascomycota|Rep: Fumarylacetoacetate
           hydrolase family protein - Aspergillus fumigatus
           (Sartorya fumigata)
          Length = 235

 Score = 85.4 bits (202), Expect = 1e-15
 Identities = 73/205 (35%), Positives = 105/205 (51%), Gaps = 22/205 (10%)

Query: 84  LNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQ-PVRIRTDVTKKVDWEVELCVVVG--- 139
           LN     +E N T P  P  F K  S+I+ P + PV +   V+  + +EVEL +V+G   
Sbjct: 20  LNKSQLQKELNNTKPKQPFFFLKPPSSILLPREGPVLLPKGVS--LHYEVELALVMGKTV 77

Query: 140 REASCVREEDALQHVAGYTVAQDISARDWQKE-KNMG-QFLLGKSMDTFCPLG---PCVL 194
           R+     E+ AL  +  Y +A D++ R+ Q E K  G  + + K  DTF P+    P   
Sbjct: 78  RDLDPNDEKGALDAIRSYLLAIDMTGRNVQDEAKKKGLPWSIAKGFDTFLPISEEIPKAR 137

Query: 195 TSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPGDLILTGTPGG 254
             D   A + L    S+   L+Q+ ST  +++ IP  L  IS VMTL  GDL+LTGTP G
Sbjct: 138 IPDPHNAFLRL----SVGSQLRQADSTGLMLYRIPRQLAEISRVMTLEKGDLVLTGTPKG 193

Query: 255 VGMYRQPPEYLQPGDVLTSEIEKIG 279
           VG        ++ GDV+ + IE  G
Sbjct: 194 VG-------EVKAGDVMKASIEVDG 211


>UniRef50_Q89FA1 Cluster: Bll6800 protein; n=3; Proteobacteria|Rep:
           Bll6800 protein - Bradyrhizobium japonicum
          Length = 276

 Score = 85.0 bits (201), Expect = 2e-15
 Identities = 66/235 (28%), Positives = 110/235 (46%), Gaps = 22/235 (9%)

Query: 62  IPLSSVTLTAP--IHGVDKILCIGLNYKDHCQEQNLTPP-PVPMVFSKFSSTI----IGP 114
           +P+ ++ +     +  V +I CIG NY  H  E+   P    P  F K +  I    +G 
Sbjct: 52  VPMVAIPIVGETQVFQVRRIYCIGRNYAAHAIERGSDPNREPPFFFQKPTDAIQNVAVGE 111

Query: 115 --DQPVRIRTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQK-- 170
             D P      +TK    E+EL   +    + +  E AL HV GY +  D++ RD Q   
Sbjct: 112 VADHPY---PSLTKNYHHEIELVAALKSGGTNIPAEKALDHVYGYALGLDMTRRDLQNGM 168

Query: 171 EKNMGQFLLGKSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPS 230
                 + +GKS D    LGP +  + + G   +  +S ++NG +KQSS  ++++ S+  
Sbjct: 169 AAEKKPWEIGKSFDHAAVLGP-IHPASKTGHFEKGAISLAINGTVKQSSDLSKMIWSVAE 227

Query: 231 LLHRISSVMTLVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIGAFDVRI 285
            + ++S    L  GD+I +GTP  VG        +  GDVL  ++E +    ++I
Sbjct: 228 QIAKLSEAFELKAGDIIYSGTPENVGP-------VVKGDVLLCKLEGLPDMSIKI 275


  Database: uniref50
    Posted date:  Oct 5, 2007 11:19 AM
  Number of letters in database: 575,637,011
  Number of sequences in database:  1,657,284
  
Lambda     K      H
   0.317    0.136    0.397 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 333,794,440
Number of Sequences: 1657284
Number of extensions: 14078967
Number of successful extensions: 34335
Number of sequences better than 10.0: 350
Number of HSP's better than 10.0 without gapping: 316
Number of HSP's successfully gapped in prelim test: 34
Number of HSP's that attempted gapping in prelim test: 33328
Number of HSP's gapped (non-prelim): 389
length of query: 288
length of database: 575,637,011
effective HSP length: 100
effective length of query: 188
effective length of database: 409,908,611
effective search space: 77062818868
effective search space used: 77062818868
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
S2: 72 (33.1 bits)

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