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Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= BGIBMGA000032-TA|BGIBMGA000032-
PA|IPR005135|Endonuclease/exonuclease/phosphatase, IPR000300|Inositol
polyphosphate related phosphatase
         (656 letters)

Database: uniref50 
           1,657,284 sequences; 575,637,011 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

UniRef50_UPI0000D57083 Cluster: PREDICTED: similar to CG31110-PA...   345   2e-93
UniRef50_Q8IGM4 Cluster: RE64196p; n=9; Endopterygota|Rep: RE641...   325   3e-87
UniRef50_Q14642 Cluster: Type I inositol-1,4,5-trisphosphate 5-p...   225   4e-57
UniRef50_A7RGY0 Cluster: Predicted protein; n=1; Nematostella ve...   194   6e-48
UniRef50_Q28CJ9 Cluster: Inositol polyphosphate-5-phosphatase, 4...   191   4e-47
UniRef50_Q4SVK7 Cluster: Chromosome undetermined SCAF13756, whol...   191   6e-47
UniRef50_Q4RN66 Cluster: Chromosome undetermined SCAF15016, whol...   186   2e-45
UniRef50_Q17848 Cluster: Probable type I inositol-1,4,5-trisphos...   146   1e-33
UniRef50_UPI000058474C Cluster: PREDICTED: similar to type I ino...   108   4e-22
UniRef50_UPI000069E17E Cluster: UPI000069E17E related cluster; n...    77   1e-12
UniRef50_Q4E3P6 Cluster: Inositol-1,4,5-trisphosphate (IP3) 5-ph...    64   1e-08
UniRef50_Q16HV3 Cluster: Type i inositol-1,4,5-trisphosphate 5-p...    61   1e-07
UniRef50_Q4QGX8 Cluster: Inositol-1,4,5-trisphosphate (IP3) 5-ph...    50   1e-04
UniRef50_Q17543 Cluster: Putative uncharacterized protein; n=2; ...    39   0.48 
UniRef50_UPI000069E17F Cluster: UPI000069E17F related cluster; n...    38   1.1  
UniRef50_A7FPS5 Cluster: N-acetylmuramoyl-L-alanine amidase-like...    38   1.1  
UniRef50_A1B6K3 Cluster: Putative uncharacterized protein; n=5; ...    36   2.6  
UniRef50_Q8N813 Cluster: Putative uncharacterized protein C3orf5...    36   3.4  
UniRef50_Q3A831 Cluster: Aminopeptidase A/I; n=1; Pelobacter car...    36   4.5  
UniRef50_A5JZI4 Cluster: Putative uncharacterized protein; n=1; ...    35   6.0  
UniRef50_Q9PCI4 Cluster: Type III pantothenate kinase; n=12; Xan...    35   6.0  

>UniRef50_UPI0000D57083 Cluster: PREDICTED: similar to CG31110-PA;
           n=1; Tribolium castaneum|Rep: PREDICTED: similar to
           CG31110-PA - Tribolium castaneum
          Length = 611

 Score =  345 bits (849), Expect = 2e-93
 Identities = 163/269 (60%), Positives = 196/269 (72%), Gaps = 4/269 (1%)

Query: 1   MLPIWTSEFLQAVSRMDPKFIALHLQEVGGKAYEKSMQYVKDFVQRLCDCPELRLFDKIR 60
           ML IWT EFL  V+++DPKFIALH QEVGGK YE SM++V+ FV+ L    ELRLFDKIR
Sbjct: 25  MLKIWTEEFLSTVTKLDPKFIALHCQEVGGKNYENSMKHVEHFVKLLMSSNELRLFDKIR 84

Query: 61  IYLDEDFSSPEKFTALGNMYFAHSSLVDLKIWDFDLKAYVDVVGKEIHSGNIENASTKEK 120
           I+LDED+SS E FTALGN+YF H S+ ++ IWDF+   +V V  K +HSGNIE  +TKEK
Sbjct: 85  IFLDEDYSSAENFTALGNLYFIHESVENVLIWDFNDVKFVPVSDKLVHSGNIEAIATKEK 144

Query: 121 AKFPQHFFPECKWSRKGFLRTRWTIRGTAVEFVNIHLFHDASNLVAMEPFPSVYCXXXXX 180
           AKFPQ FFPECKWSRKGFLRTRW++ GT ++ VNIHLFHDASN +AME +PSVYC     
Sbjct: 145 AKFPQDFFPECKWSRKGFLRTRWSLNGTVLDLVNIHLFHDASNFIAMESYPSVYCKNRRR 204

Query: 181 XXXXXXXXXHADG-SAAPYFIFGDFNFRTDTAGVVKKVTEDLSAQRVQGGAEGG--RLQY 237
                    H D    APYF+FGDFNFRTDT GV+KK+TE L+  R+Q        +LQ+
Sbjct: 205 ALEHTLQRFHNDRYGKAPYFVFGDFNFRTDTEGVIKKLTEGLTTTRLQNNKNNDYTKLQF 264

Query: 238 RRRADQRLVLTVGKKEFAHVDHQKIFREP 266
               D +LVLTVGKKEF H+DHQK+F  P
Sbjct: 265 ANE-DSQLVLTVGKKEFNHLDHQKVFLTP 292



 Score = 55.6 bits (128), Expect = 4e-06
 Identities = 25/53 (47%), Positives = 35/53 (66%)

Query: 301 RKPSYTASSRRLQRYDRELEALRPHLFEFPVKFPPTYPFEEDVLLPTHYMKTR 353
           +K   T S   L+ +D+ELEA   +L E+P+ FPP+YPFEE+V     YM+TR
Sbjct: 286 QKVFLTPSPTWLKTFDKELEAFEKYLTEYPITFPPSYPFEENVSHARSYMQTR 338


>UniRef50_Q8IGM4 Cluster: RE64196p; n=9; Endopterygota|Rep: RE64196p
           - Drosophila melanogaster (Fruit fly)
          Length = 699

 Score =  325 bits (798), Expect = 3e-87
 Identities = 156/292 (53%), Positives = 195/292 (66%), Gaps = 10/292 (3%)

Query: 1   MLPIWTSEFLQAVSRMDPKFIALHLQEVGGKAYEKSMQYVKDFVQRLCDCPELRLFDKIR 60
           +L +W SEFL  ++   P+F+ALHLQEVGGK YEKSM+YV++F++ LCD PE+  F  + 
Sbjct: 30  LLQLWLSEFLAKIAVAQPRFLALHLQEVGGKTYEKSMEYVQEFIRCLCDAPEMGDFTCVH 89

Query: 61  IYLDEDFSSPEKFTALGNMYFAHSSLVDLKIWDFDLKAYV----DVVGKEIHSGNIENAS 116
           I++DEDF S E FTALG++YF H  +  LKIW+F   ++     DV  K I+SGNIE  +
Sbjct: 90  IFMDEDFKSAEHFTALGSLYFVHKDVASLKIWNFLTHSWEESLQDVKDKHIYSGNIETIA 149

Query: 117 TKEKAKFPQHFFPECKWSRKGFLRTRWTIRGTAVEFVNIHLFHDASNLVAMEPFPSVYCX 176
           TKEK+KFPQHFFPECKWSRKGF+RTRW I GT ++ VNIHLFHDASNL A E FPSVYC 
Sbjct: 150 TKEKSKFPQHFFPECKWSRKGFMRTRWEINGTVIDLVNIHLFHDASNLAACENFPSVYCK 209

Query: 177 XXXXXXXXXXXXXHAD--GSAAPYFIFGDFNFRTDTAGVVKKVTEDLSAQRVQG-GAEGG 233
                        H D      P+F+FGDFNFR DT GVVK++TE+L+  RVQ    E  
Sbjct: 210 TRRRALVHTIERFHLDEQNGTVPFFLFGDFNFRCDTEGVVKELTENLTPHRVQNVKNEND 269

Query: 234 RLQYRRRADQRLVLTVGKKEFAHVDHQKIFREPWVR--DLPTPPSHYRLVSY 283
           ++ YR       VLTVGKKEF+H DHQ  F+E W++  D    P    LV Y
Sbjct: 270 KIHYRNSTGNN-VLTVGKKEFSHADHQLKFKEDWLKKFDRELEPLKDVLVEY 320



 Score = 60.5 bits (140), Expect = 1e-07
 Identities = 25/42 (59%), Positives = 33/42 (78%)

Query: 312 LQRYDRELEALRPHLFEFPVKFPPTYPFEEDVLLPTHYMKTR 353
           L+++DRELE L+  L E+P+KF P+YPFEED  +PT YM TR
Sbjct: 303 LKKFDRELEPLKDVLVEYPIKFVPSYPFEEDPEMPTDYMSTR 344



 Score = 39.5 bits (88), Expect = 0.28
 Identities = 14/25 (56%), Positives = 20/25 (80%)

Query: 464 VIGDTACMGDHKPIYLRVMLQADRG 488
           +IG+  CMGDHKP+YL V L+ ++G
Sbjct: 371 MIGEAVCMGDHKPVYLTVRLKPNKG 395


>UniRef50_Q14642 Cluster: Type I inositol-1,4,5-trisphosphate
           5-phosphatase; n=39; Euteleostomi|Rep: Type I
           inositol-1,4,5-trisphosphate 5-phosphatase - Homo
           sapiens (Human)
          Length = 412

 Score =  225 bits (549), Expect = 4e-57
 Identities = 116/264 (43%), Positives = 153/264 (57%), Gaps = 3/264 (1%)

Query: 5   WTSEFLQAVSRMDPKFIALHLQEVGGKAYEKSMQYVKDFVQRLCDCPELRLFDKIRIYLD 64
           W  EF Q V    P F+ALH QE GGK YE SM +V  FV+ L     ++ +++ R+YLD
Sbjct: 33  WLREFYQVVHTHKPHFMALHCQEFGGKNYEASMSHVDKFVKELLSSDAMKEYNRARVYLD 92

Query: 65  EDFSSPEKFTALGNMYFAHSSLVDLKIWDFDLKAYVDVVGKEIHSGNIENASTKEKAKFP 124
           E++ S E FTALG+ YF H SL ++  +DF  K Y  V GKEI+S  +E+    EK KFP
Sbjct: 93  ENYKSQEHFTALGSFYFLHESLKNIYQFDFKAKKYRKVAGKEIYSDTLESTPMLEKEKFP 152

Query: 125 QHFFPECKWSRKGFLRTRWTIRGTAVEFVNIHLFHDASNLVAMEPFPSVYC-XXXXXXXX 183
           Q +FPECKWSRKGF+RTRW I   A + VNIHLFHDASNLVA E  PSVY          
Sbjct: 153 QDYFPECKWSRKGFIRTRWCIADCAFDLVNIHLFHDASNLVAWETSPSVYSGIRHKALGY 212

Query: 184 XXXXXXHADGSAAPYFIFGDFNFRTDTAGVVKKVTEDLSAQRVQGG--AEGGRLQYRRRA 241
                         YF+FGDFNFR D+  VV+ +    + Q V+     E  +L +R   
Sbjct: 213 VLDRIIDQRFEKVSYFVFGDFNFRLDSKSVVETLCTKATMQTVRAADTNEVVKLIFRESD 272

Query: 242 DQRLVLTVGKKEFAHVDHQKIFRE 265
           + R V+   +K+     +Q++FR+
Sbjct: 273 NDRKVMLQLEKKLFDYFNQEVFRD 296



 Score = 44.8 bits (101), Expect = 0.007
 Identities = 17/42 (40%), Positives = 24/42 (57%)

Query: 312 LQRYDRELEALRPHLFEFPVKFPPTYPFEEDVLLPTHYMKTR 353
           L  +D+EL   +  L+E  + FPP+YP+ ED      YM TR
Sbjct: 302 LLEFDKELSVFKDRLYELDISFPPSYPYSEDARQGEQYMNTR 343


>UniRef50_A7RGY0 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 404

 Score =  194 bits (473), Expect = 6e-48
 Identities = 104/266 (39%), Positives = 149/266 (56%), Gaps = 7/266 (2%)

Query: 4   IWTSEFLQAVSRMDPKFIALHLQEVGGK-AYEKSMQYVKDFVQRLCDCPELRL-FDKIRI 61
           IW  + L+   + DP F+ALH QE GGK A E + + V+DF + L    ++ L FD+   
Sbjct: 28  IWVEKILETFEKFDPSFVALHFQECGGKVAAEAAFESVEDFTRALLKNEKICLRFDRRFA 87

Query: 62  YLDEDFSSPEKFTALGNMYFAHSSLVDLKIWDFDLKAYVDVVGKEIHSGNIENASTKEKA 121
           ++D+DF   EKFTALG +YF   SL ++ +W+     +V    +EI  G++ + S  +K 
Sbjct: 88  WIDQDFQKAEKFTALGCIYFIKKSLKNILVWNHQESQFVSTKVEEIKVGDLSDVSCVQKL 147

Query: 122 KFPQHFFPECKWSRKGFLRTRWTIRGTAVEFVNIHLFHDASNLVAMEPFPSVYCXXXXXX 181
           KFP+ FFP+ KWSRKGF+RTRW I     + +NIHLFHDASNL AM+  PS Y       
Sbjct: 148 KFPREFFPQLKWSRKGFMRTRWKINNCIFDLLNIHLFHDASNLEAMQMSPSDYSQARHRA 207

Query: 182 XXXXXXXXHADG-SAAPYFIFGDFNFRTDTAGVVKKVTEDLSAQRVQGGAEG--GRLQYR 238
                     D    AP  +FGDFNFR DT  VV+ +   L +Q ++   E    ++ +R
Sbjct: 208 LKHILERLENDSLPKAPCILFGDFNFRLDTKAVVESLCAGLQSQYIRKDGESIPSKVLFR 267

Query: 239 -RRADQRLVLTVGKKEFAHVDHQKIF 263
            ++   ++VL V  K+F  V  Q  F
Sbjct: 268 DKKISDKVVLAVETKKFV-VHDQSYF 292



 Score = 47.2 bits (107), Expect = 0.001
 Identities = 16/39 (41%), Positives = 27/39 (69%)

Query: 305 YTASSRRLQRYDRELEALRPHLFEFPVKFPPTYPFEEDV 343
           ++   +R Q+Y+RE E  +  L+EF + FPP+YPF +D+
Sbjct: 293 HSEDGKRFQKYNREFEEFQNKLYEFNISFPPSYPFSDDI 331


>UniRef50_Q28CJ9 Cluster: Inositol polyphosphate-5-phosphatase,
           40kDa; n=3; Euteleostomi|Rep: Inositol
           polyphosphate-5-phosphatase, 40kDa - Xenopus tropicalis
           (Western clawed frog) (Silurana tropicalis)
          Length = 432

 Score =  191 bits (466), Expect = 4e-47
 Identities = 89/170 (52%), Positives = 113/170 (66%)

Query: 5   WTSEFLQAVSRMDPKFIALHLQEVGGKAYEKSMQYVKDFVQRLCDCPELRLFDKIRIYLD 64
           W  EF Q V    P+F++LH QEVGGK YE SM +V   V+ L     ++ F++ R+YLD
Sbjct: 33  WLREFYQTVHAQKPQFLSLHCQEVGGKNYEASMAHVDKLVKDLLSSDAMKEFNRARVYLD 92

Query: 65  EDFSSPEKFTALGNMYFAHSSLVDLKIWDFDLKAYVDVVGKEIHSGNIENASTKEKAKFP 124
           E++ S E FTALG+ YF H SL ++  +DF  K Y  V GKEI+S  +E+    EK KFP
Sbjct: 93  ENYKSQENFTALGSFYFLHESLKNVYQYDFKAKKYRKVTGKEIYSDTLESTPMLEKEKFP 152

Query: 125 QHFFPECKWSRKGFLRTRWTIRGTAVEFVNIHLFHDASNLVAMEPFPSVY 174
           Q FFPE K SRKGF+RTRW I   A + VNIHLFHDASN++A E  PS+Y
Sbjct: 153 QEFFPESKSSRKGFIRTRWCITDCAFDLVNIHLFHDASNVIAWESSPSIY 202



 Score = 45.2 bits (102), Expect = 0.006
 Identities = 25/72 (34%), Positives = 41/72 (56%), Gaps = 4/72 (5%)

Query: 197 PYFIFGDFNFRTDTAGVVKKVTEDLSAQRVQGGAEGG--RLQYRR-RADQRLVLTVGKKE 253
           P+F+FGDFNFR D   VV+ +    + Q V         +L +R    D+++VL + KK 
Sbjct: 246 PFFVFGDFNFRLDLKSVVETLCAKTTMQTVHAADTNAVDKLVFRESENDRKVVLQIEKKL 305

Query: 254 FAHVDHQKIFRE 265
           F +  +Q++FR+
Sbjct: 306 FEYF-NQEVFRD 316



 Score = 43.6 bits (98), Expect = 0.017
 Identities = 17/42 (40%), Positives = 24/42 (57%)

Query: 312 LQRYDRELEALRPHLFEFPVKFPPTYPFEEDVLLPTHYMKTR 353
           L  +D+EL   +  L+E  + FPP+YP+ ED      YM TR
Sbjct: 322 LLEFDKELSVFKDRLYELDITFPPSYPYSEDSSQGKQYMNTR 363


>UniRef50_Q4SVK7 Cluster: Chromosome undetermined SCAF13756, whole
           genome shotgun sequence; n=2; Tetraodontidae|Rep:
           Chromosome undetermined SCAF13756, whole genome shotgun
           sequence - Tetraodon nigroviridis (Green puffer)
          Length = 417

 Score =  191 bits (465), Expect = 6e-47
 Identities = 89/208 (42%), Positives = 128/208 (61%), Gaps = 1/208 (0%)

Query: 9   FLQAVSRMDPKFIALHLQEVGGKAYEKSMQYVKDFVQRLCDCPELRLFDKIRIYLDEDFS 68
           FLQ +    P+FIALH QEVGGK Y  +M + ++F   +    E++ +D++ +Y+D DF 
Sbjct: 97  FLQTIQSHKPQFIALHFQEVGGKDYMVNMSHAENFFWDIESSAEMKDYDRVCVYVDADFQ 156

Query: 69  SPEKFTALGNMYFAHSSLVDLKIWDFDLKAYVDVVGKEIHSGNIENASTKEKAKFPQHFF 128
           + + FTALG+MYF H++L ++  +DF  + Y  V G   H  ++   +T EK KFP++F+
Sbjct: 157 AEDSFTALGSMYFIHNTLKNIYQYDFQDEDYKAVSGHSRHVASLNGITTVEKEKFPKNFW 216

Query: 129 PECKWSRKGFLRTRWTIRGTAVEFVNIHLFHDASNLVAMEPFPSVY-CXXXXXXXXXXXX 187
           P+ KWSRKGF+RTRW I    ++ VNIHLFHDASNL+A    PS+Y              
Sbjct: 217 PDFKWSRKGFMRTRWIIHNQFLDLVNIHLFHDASNLIACNSSPSIYSANRKNALRYVINR 276

Query: 188 XXHADGSAAPYFIFGDFNFRTDTAGVVK 215
              A    AP+F+FGDFNFR D   +V+
Sbjct: 277 ISDARHPPAPFFLFGDFNFRLDALSLVQ 304



 Score = 46.4 bits (105), Expect = 0.002
 Identities = 19/46 (41%), Positives = 29/46 (63%)

Query: 308 SSRRLQRYDRELEALRPHLFEFPVKFPPTYPFEEDVLLPTHYMKTR 353
           + R L +YD+E+ A    + E  ++FPP+YP+ E+   PT YM TR
Sbjct: 326 NGRALLKYDKEVSAFYDVIREENIQFPPSYPYSEEYSQPTQYMNTR 371


>UniRef50_Q4RN66 Cluster: Chromosome undetermined SCAF15016, whole
           genome shotgun sequence; n=2; Deuterostomia|Rep:
           Chromosome undetermined SCAF15016, whole genome shotgun
           sequence - Tetraodon nigroviridis (Green puffer)
          Length = 600

 Score =  186 bits (452), Expect = 2e-45
 Identities = 99/232 (42%), Positives = 130/232 (56%), Gaps = 26/232 (11%)

Query: 11  QAVSRMDPKFIALHLQEVGGKAYEKSMQYVKDFVQRLCDCPELRLFDKIRIYLDEDFSSP 70
           Q V    P F+ALH QEVGGK YE SM +V  FV+ L     ++ +++ R+YLD+++ S 
Sbjct: 1   QTVHTYKPHFLALHCQEVGGKNYEASMSHVDSFVKELLSSDTMKDYNRARVYLDKNYKSQ 60

Query: 71  EKFT-------------------------ALGNMYFAHSSLVDLKIWDFDLKAYVDVVGK 105
           E FT                         ALG+ YF H SL ++  +DF  K +  +VGK
Sbjct: 61  EHFTPQRGQNEGSLTNKLSLGALQRQNPQALGSFYFIHESLKNIHQFDFKAKKFKKLVGK 120

Query: 106 EIHSGNIENASTKEKAKFPQHFFPECKWSRKGFLRTRWTIRGTAVEFVNIHLFHDASNLV 165
           E +S  +E+  T EK KFPQ +FPECKWSRKGF+RTRW +   A + VNIHLFHDASNLV
Sbjct: 121 ETYSETLESTPTMEKEKFPQDYFPECKWSRKGFIRTRWALPDCAFDLVNIHLFHDASNLV 180

Query: 166 AMEPFPSVYC-XXXXXXXXXXXXXXHADGSAAPYFIFGDFNFRTDTAGVVKK 216
           A E  PSVY                       P+F+FGDFNFR D+  V+++
Sbjct: 181 AWEKSPSVYSGTRQKALGFVLDRITDQRYEKVPHFVFGDFNFRLDSKQVIEE 232



 Score = 45.2 bits (102), Expect = 0.006
 Identities = 19/47 (40%), Positives = 26/47 (55%)

Query: 307 ASSRRLQRYDRELEALRPHLFEFPVKFPPTYPFEEDVLLPTHYMKTR 353
           A + +L  YD+EL   +  L E  + FPP+YP+ ED      YM TR
Sbjct: 511 ALATKLLEYDKELSVFKDRLHELEISFPPSYPYSEDSNQGKQYMNTR 557


>UniRef50_Q17848 Cluster: Probable type I
           inositol-1,4,5-trisphosphate 5-phosphatase; n=2;
           Caenorhabditis|Rep: Probable type I
           inositol-1,4,5-trisphosphate 5-phosphatase -
           Caenorhabditis elegans
          Length = 409

 Score =  146 bits (355), Expect = 1e-33
 Identities = 109/355 (30%), Positives = 158/355 (44%), Gaps = 22/355 (6%)

Query: 5   WTSEFLQAVSRMDPKFIALHLQEVGGKAYEKSMQYVKDFVQRLCDCPELRLFDKIRIYLD 64
           W       V  +DP F  +HLQE GGK + +  Q V   + RL     L  FD +R Y+D
Sbjct: 25  WIKTVADQVESVDPSFFVIHLQETGGKKFTECSQQVPIIINRLSTA--LPKFDLLRAYVD 82

Query: 65  EDFSSPEKFTALGNMYFAHSSL-VDLKIWDFDLKAYVDVVG-KEIHSGNIENASTKEKAK 122
            D+ + E +TALG + F   SL  ++  ++F  K Y  +   KE+ +  +EN     K K
Sbjct: 83  IDYEAIE-YTALGALCFIKRSLWSNVSQFNFHTKKYEQLTSPKEVVTHGLENYPYVVKHK 141

Query: 123 FPQHFFPECKWSRKGFLRTRWTIRGTAVEFVNIHLFHDASNLVAMEPFPSVYC--XXXXX 180
           FP+ F+P  KW RKG+++TRW I     +FVN HLFHD SNL  +   P +Y        
Sbjct: 142 FPKDFWPSIKWGRKGYMQTRWKIENKVFDFVNAHLFHDESNLALIHENPQLYSQNRKRAL 201

Query: 181 XXXXXXXXXHADGSAAPYFIFGDFNFRTDTAGVVKKVTEDLSAQRVQGGAEGGRLQ--YR 238
                      +G     F+FGD NFR D+   + ++TE  +   V    + G L    +
Sbjct: 202 DFVLAELSSKENGCTPLLFVFGDLNFRLDSRSFLNRLTERTAQHPVADQEQMGSLADGLQ 261

Query: 239 RRADQRLVLTVGKKEFAHVDHQKIFREPWVRDLPTPPSHYRLVSYQGQSGRLVVEGFLAR 298
             A    V+T   +          FR    R+  +  S    V       R+  + F   
Sbjct: 262 ASAANLQVITHPSENLRRTVSAIEFR----RESDSDDSQNSCVL------RIEKKKFDYF 311

Query: 299 RKRKPSYTASSRRLQRYDRELEALRPHLFEFPVKFPPTYPFEEDVLLPTHYMKTR 353
             +K       R  +  D+E E  +  +FE  + FPPTYP+ ED       MKTR
Sbjct: 312 NHKK--LLDDWRSYRDDDKETENFQ-SMFEMHINFPPTYPWSEDPENSETLMKTR 363


>UniRef50_UPI000058474C Cluster: PREDICTED: similar to type I
           inositol 1,4,5-trisphosphate 5-phosphatase; n=1;
           Strongylocentrotus purpuratus|Rep: PREDICTED: similar to
           type I inositol 1,4,5-trisphosphate 5-phosphatase -
           Strongylocentrotus purpuratus
          Length = 345

 Score =  108 bits (260), Expect = 4e-22
 Identities = 58/143 (40%), Positives = 79/143 (55%), Gaps = 4/143 (2%)

Query: 122 KFPQHFFPECKWSRKGFLRTRWTIRGTAVEFVNIHLFHDASNLVAME-PFPSVYCXXXXX 180
           K P+ F   CKWSRKGF+RTRW+I G   E VN+HLFHDA+N++A+E  FPS Y      
Sbjct: 93  KTPECF--TCKWSRKGFMRTRWSINGRQYELVNVHLFHDANNVIAVETQFPSQYSKTRRK 150

Query: 181 XXXXXXXXXHAD-GSAAPYFIFGDFNFRTDTAGVVKKVTEDLSAQRVQGGAEGGRLQYRR 239
                      +  S  P+FIFGDFNFR D  GVVK +         +      R++Y  
Sbjct: 151 GLEFVIQRLSQEKHSRVPFFIFGDFNFRLDAQGVVKALVLQAKPTYTKKDGAITRIEYSD 210

Query: 240 RADQRLVLTVGKKEFAHVDHQKI 262
             + +++LT+ KK+F   D  +I
Sbjct: 211 ENNSQVLLTLEKKKFEMDDPDRI 233



 Score = 83.4 bits (197), Expect = 2e-14
 Identities = 35/74 (47%), Positives = 53/74 (71%)

Query: 1  MLPIWTSEFLQAVSRMDPKFIALHLQEVGGKAYEKSMQYVKDFVQRLCDCPELRLFDKIR 60
          M+ IW  +  + + R++P FIALH QE+GGK +E SMQ+V +FVQ+L D   L+ FD+  
Sbjct: 26 MMSIWLDKLYETIKRLEPHFIALHCQELGGKDFEVSMQHVDNFVQKLYDSEALQDFDRSS 85

Query: 61 IYLDEDFSSPEKFT 74
          ++LD++F +PE FT
Sbjct: 86 VFLDKEFKTPECFT 99



 Score = 43.2 bits (97), Expect = 0.023
 Identities = 18/42 (42%), Positives = 24/42 (57%)

Query: 312 LQRYDRELEALRPHLFEFPVKFPPTYPFEEDVLLPTHYMKTR 353
           L R+D+E       L E+ V F P+YP+ ED+     YMKTR
Sbjct: 241 LSRFDKEFSCFTKQLLEYDVTFQPSYPYSEDISDGHSYMKTR 282


>UniRef50_UPI000069E17E Cluster: UPI000069E17E related cluster; n=1;
           Xenopus tropicalis|Rep: UPI000069E17E UniRef100 entry -
           Xenopus tropicalis
          Length = 158

 Score = 77.4 bits (182), Expect = 1e-12
 Identities = 39/118 (33%), Positives = 65/118 (55%)

Query: 13  VSRMDPKFIALHLQEVGGKAYEKSMQYVKDFVQRLCDCPELRLFDKIRIYLDEDFSSPEK 72
           + R +P+FIA+HLQE GGK YEK+M+  +  ++ L   P + L D +  Y+         
Sbjct: 41  IHRCNPEFIAMHLQEFGGKEYEKNMEAAEKLIRCLFAAPHMMLTDSLPCYILLTAILFFI 100

Query: 73  FTALGNMYFAHSSLVDLKIWDFDLKAYVDVVGKEIHSGNIENASTKEKAKFPQHFFPE 130
             ALG++Y  H SL  ++I++F  K +    G  +  G++ +    +K +FPQ F+ E
Sbjct: 101 LQALGSIYLIHKSLNRIQIYNFKEKHFATFSGHNLFLGSLGDCPLVQKERFPQDFWKE 158


>UniRef50_Q4E3P6 Cluster: Inositol-1,4,5-trisphosphate (IP3)
           5-phosphatase, putative; n=3; Trypanosoma|Rep:
           Inositol-1,4,5-trisphosphate (IP3) 5-phosphatase,
           putative - Trypanosoma cruzi
          Length = 580

 Score = 64.1 bits (149), Expect = 1e-08
 Identities = 58/202 (28%), Positives = 84/202 (41%), Gaps = 14/202 (6%)

Query: 21  IALHLQEVGGKAYEKSMQ-YVKDFVQRLCDCPELRLFDKIRIYLDEDFSSPEKFTALGNM 79
           I +H QE+GGK    +   +  + ++ L   PE      +   L E  S  ++FTALG++
Sbjct: 184 IVVHFQEIGGKGANTAFNAFFAEALKTLL--PEAAWSSGL---LMETNSDMQRFTALGSI 238

Query: 80  YFAHSSLVDLK-IWDFDLKAYVDVVGKEIHSGNIENASTKEKAKFPQHFFPECKWSRKGF 138
            F  S +  +  I  F  + +V V       G+           F    F      RKGF
Sbjct: 239 VFLSSRMCPISSILSFRHRTFVAVADDPATYGS------SPTFLFHGGKFSGAGSGRKGF 292

Query: 139 LRTRWTIRGTAVEFVNIHLFHDASNLVAMEPFPSVYCXXXXXXXXXXXXXXHADGSAA-P 197
           L T        V ++N+HL+HD+ N  A    PS+Y                   S   P
Sbjct: 293 LLTSLRFGTVVVNYLNVHLYHDSRNTDAAMTSPSLYSVQRQEALLEAMAECMVFISPEDP 352

Query: 198 YFIFGDFNFRTDTAGVVKKVTE 219
            FIFGDFN R DT  ++K + E
Sbjct: 353 LFIFGDFNARLDTHNLLKHLKE 374


>UniRef50_Q16HV3 Cluster: Type i inositol-1,4,5-trisphosphate
           5-phosphatase; n=1; Aedes aegypti|Rep: Type i
           inositol-1,4,5-trisphosphate 5-phosphatase - Aedes
           aegypti (Yellowfever mosquito)
          Length = 648

 Score = 60.9 bits (141), Expect = 1e-07
 Identities = 32/93 (34%), Positives = 47/93 (50%)

Query: 261 KIFREPWVRDLPTPPSHYRLVSYQGQSGRLVVEGFLARRKRKPSYTASSRRLQRYDRELE 320
           K+  +  +  +P P S    V Y+   G  V+             T     L+++DREL+
Sbjct: 40  KLTEDLTMHRIPHPKSDNSKVQYRDSDGANVLTLGKKEFNHHDQSTFKENWLRQFDRELD 99

Query: 321 ALRPHLFEFPVKFPPTYPFEEDVLLPTHYMKTR 353
           +LR  L E+P+ FPP+YP+EED   P  YM TR
Sbjct: 100 SLRSILHEYPITFPPSYPYEEDPGQPGSYMSTR 132



 Score = 45.2 bits (102), Expect = 0.006
 Identities = 26/58 (44%), Positives = 37/58 (63%), Gaps = 3/58 (5%)

Query: 213 VVKKVTEDLSAQRV-QGGAEGGRLQYRRRADQRLVLTVGKKEFAHVDHQKIFREPWVR 269
           V  K+TEDL+  R+    ++  ++QYR  +D   VLT+GKKEF H D Q  F+E W+R
Sbjct: 37  VFVKLTEDLTMHRIPHPKSDNSKVQYRD-SDGANVLTLGKKEFNHHD-QSTFKENWLR 92



 Score = 36.7 bits (81), Expect = 2.0
 Identities = 12/27 (44%), Positives = 20/27 (74%)

Query: 464 VIGDTACMGDHKPIYLRVMLQADRGRL 490
           ++G+  CMGDHKP++L V ++  +G L
Sbjct: 164 IMGEVVCMGDHKPVFLNVRIKTTQGIL 190


>UniRef50_Q4QGX8 Cluster: Inositol-1,4,5-trisphosphate (IP3)
           5-phosphatase, putative; n=3; Leishmania|Rep:
           Inositol-1,4,5-trisphosphate (IP3) 5-phosphatase,
           putative - Leishmania major
          Length = 688

 Score = 50.4 bits (115), Expect = 1e-04
 Identities = 31/95 (32%), Positives = 41/95 (43%), Gaps = 1/95 (1%)

Query: 128 FPECKWSRKGFLRTRWTIRGTAVEFVNIHLFHDASNLVAMEPFPSVYCXXXXXXXXXXXX 187
           F E   SRKGFL     +        N+HLF+D  N VA++  PS+Y             
Sbjct: 354 FAEAGRSRKGFLLLSLRLGTVQFNVCNVHLFNDDDNRVALKSSPSLYTGRRTRAITEAIA 413

Query: 188 XXHA-DGSAAPYFIFGDFNFRTDTAGVVKKVTEDL 221
              A    + P FIFGD+N R D     + V E +
Sbjct: 414 ECSAVVDLSEPLFIFGDYNVRMDGKSFTEWVEEKM 448


>UniRef50_Q17543 Cluster: Putative uncharacterized protein; n=2;
           Caenorhabditis|Rep: Putative uncharacterized protein -
           Caenorhabditis elegans
          Length = 402

 Score = 38.7 bits (86), Expect = 0.48
 Identities = 46/172 (26%), Positives = 75/172 (43%), Gaps = 26/172 (15%)

Query: 1   MLPIWTSEFLQAVSRMDPKFIALHLQEVGGKAYEKSMQYVKDFVQRLCDCPEL-RLFDKI 59
           ++  W SE  + +     +F  +H+Q  G  + E      +     + D PE+ R FD  
Sbjct: 23  LIRAWCSEVAKEIYEQKCEFAVVHVQ--GLHSAENPDYAARVICGCITDNPEIYRAFDSS 80

Query: 60  RIYLDEDFSSPEKFTALGNMY-FAHSSLVDLKIWD-FDLKAYVDVVGKEIHS-------G 110
             + D       K T LGN+Y F + S  D++ +D F    Y++V     HS       G
Sbjct: 81  MAFFDT------KLTGLGNLYLFKNHS--DIQYYDRFSSTGYINVRSGHQHSIGSNECDG 132

Query: 111 NIENASTKEKAKFPQHFFPE-----CKWSRKGFLRTRWTIRGTAVEFVNIHL 157
            I+N +  +   F + F+ +         R GFL  R+ I G  + FVN++L
Sbjct: 133 FIQN-TFGQNYTFRRDFYNDDGTRDLANQRTGFLLARFRIHGKELTFVNLNL 183


>UniRef50_UPI000069E17F Cluster: UPI000069E17F related cluster; n=1;
           Xenopus tropicalis|Rep: UPI000069E17F UniRef100 entry -
           Xenopus tropicalis
          Length = 103

 Score = 37.5 bits (83), Expect = 1.1
 Identities = 13/24 (54%), Positives = 18/24 (75%)

Query: 330 PVKFPPTYPFEEDVLLPTHYMKTR 353
           P+ FPP+YPF ED+  P+ +M TR
Sbjct: 2   PIFFPPSYPFSEDITRPSQFMGTR 25


>UniRef50_A7FPS5 Cluster: N-acetylmuramoyl-L-alanine amidase-like
           protein; n=4; Clostridium botulinum|Rep:
           N-acetylmuramoyl-L-alanine amidase-like protein -
           Clostridium botulinum (strain ATCC 19397 / Type A)
          Length = 473

 Score = 37.5 bits (83), Expect = 1.1
 Identities = 26/78 (33%), Positives = 43/78 (55%), Gaps = 6/78 (7%)

Query: 51  PELRLFDKIRIYLDEDFSSPEKFTALGNMYFAHSSLVD----LKIWDFDLKAYVDVVGK- 105
           P + + DKI     ++F+SPEK  A  N Y+  SS+ +    L++ + D  AY  +VG+ 
Sbjct: 352 PSIYIGDKIYQKFQDEFNSPEKIYAYLNKYYTRSSINEIMNMLQVREID-GAYCKIVGQL 410

Query: 106 EIHSGNIENASTKEKAKF 123
             ++ +I NA  K K+ F
Sbjct: 411 GDYNPDILNAKIKSKSIF 428


>UniRef50_A1B6K3 Cluster: Putative uncharacterized protein; n=5;
          Rhodobacteraceae|Rep: Putative uncharacterized protein
          - Paracoccus denitrificans (strain Pd 1222)
          Length = 88

 Score = 36.3 bits (80), Expect = 2.6
 Identities = 18/54 (33%), Positives = 33/54 (61%), Gaps = 2/54 (3%)

Query: 19 KFIALHLQEVGGKAYEKSMQYVKDFVQRLCDCPELRLFDKIRIYLDEDFSSPEK 72
          +F+A ++ E G  AYE   +YV+D ++R  +  E   FD+++  L   F++PE+
Sbjct: 21 EFVASNVGENG--AYENISEYVRDLIRRDKERAEREAFDRLKAELTRAFAAPEE 72


>UniRef50_Q8N813 Cluster: Putative uncharacterized protein C3orf56;
           n=3; Catarrhini|Rep: Putative uncharacterized protein
           C3orf56 - Homo sapiens (Human)
          Length = 242

 Score = 35.9 bits (79), Expect = 3.4
 Identities = 15/26 (57%), Positives = 17/26 (65%)

Query: 319 LEALRPHLFEFPVKFPPTYPFEEDVL 344
           L AL P+LF FP+KFPPTY      L
Sbjct: 120 LAALAPNLFPFPMKFPPTYSLASPTL 145


>UniRef50_Q3A831 Cluster: Aminopeptidase A/I; n=1; Pelobacter
           carbinolicus DSM 2380|Rep: Aminopeptidase A/I -
           Pelobacter carbinolicus (strain DSM 2380 / Gra Bd 1)
          Length = 497

 Score = 35.5 bits (78), Expect = 4.5
 Identities = 20/65 (30%), Positives = 28/65 (43%), Gaps = 1/65 (1%)

Query: 86  LVDLKIWDFDLKAYVDVVGKEIHSGNIENASTKEKAKFPQHFFPECKWSRKGFLRTRWTI 145
           L  L +WD   K     +    ++G    A T   A F Q F P+C W+      T W  
Sbjct: 414 LWQLPLWDSYDKQIKSEIADMKNTGG-RPAGTITAAAFLQRFVPDCPWAHIDIAGTAWEA 472

Query: 146 RGTAV 150
           +GTA+
Sbjct: 473 KGTAL 477


>UniRef50_A5JZI4 Cluster: Putative uncharacterized protein; n=1;
            Plasmodium vivax|Rep: Putative uncharacterized protein -
            Plasmodium vivax
          Length = 1941

 Score = 35.1 bits (77), Expect = 6.0
 Identities = 18/54 (33%), Positives = 30/54 (55%), Gaps = 1/54 (1%)

Query: 95   DLKAYVDVVGKEIHSGNIENASTKEKA-KFPQHFFPECKWSRKGFLRTRWTIRG 147
            D + + + VG  I  GN+E +  KEK   + Q  +P+ +W RK + +T W  +G
Sbjct: 1625 DGEYFTNAVGTNICGGNVECSRGKEKEMNWLQMEWPQKEWPRKEWQQTEWQQKG 1678


>UniRef50_Q9PCI4 Cluster: Type III pantothenate kinase; n=12;
           Xanthomonadaceae|Rep: Type III pantothenate kinase -
           Xylella fastidiosa
          Length = 242

 Score = 35.1 bits (77), Expect = 6.0
 Identities = 19/43 (44%), Positives = 25/43 (58%)

Query: 391 GSALELDALAVPGLALSRRSIADPTSVQQAISARAGESDAWGG 433
           G+AL +D LA  G  L  R  A PT ++QA+ ARA +    GG
Sbjct: 120 GTALTIDLLAANGCHLGGRISASPTLMRQALHARAEQLPLSGG 162


  Database: uniref50
    Posted date:  Oct 5, 2007 11:19 AM
  Number of letters in database: 575,637,011
  Number of sequences in database:  1,657,284
  
Lambda     K      H
   0.321    0.136    0.416 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 673,971,326
Number of Sequences: 1657284
Number of extensions: 26288810
Number of successful extensions: 57361
Number of sequences better than 10.0: 21
Number of HSP's better than 10.0 without gapping: 16
Number of HSP's successfully gapped in prelim test: 5
Number of HSP's that attempted gapping in prelim test: 57290
Number of HSP's gapped (non-prelim): 56
length of query: 656
length of database: 575,637,011
effective HSP length: 106
effective length of query: 550
effective length of database: 399,964,907
effective search space: 219980698850
effective search space used: 219980698850
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.9 bits)
S2: 76 (34.7 bits)

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