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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= ps4M0206.Seq
         (840 letters)

Database: uniref50 
           1,657,284 sequences; 575,637,011 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

UniRef50_Q1RKZ5 Cluster: IP15551p; n=1; Drosophila melanogaster|...   145   1e-33
UniRef50_P05990 Cluster: CAD protein (Protein rudimentary) [Incl...   145   1e-33
UniRef50_A7T4N0 Cluster: Predicted protein; n=1; Nematostella ve...   129   7e-29
UniRef50_P27708 Cluster: CAD protein [Includes: Glutamine-depend...   123   5e-27
UniRef50_Q5RHG8 Cluster: Carbamoyl-phosphate synthetase 2, aspar...   120   3e-26
UniRef50_Q4SZL4 Cluster: Chromosome 14 SCAF11586, whole genome s...   120   6e-26
UniRef50_Q8U4A0 Cluster: Dihydroorotase; n=5; Thermococcaceae|Re...    77   4e-13
UniRef50_A6RFE1 Cluster: Bifunctional pyrimidine biosynthesis pr...    75   2e-12
UniRef50_A2SQD3 Cluster: Dihydroorotase, multifunctional complex...    70   6e-11
UniRef50_A1RZC7 Cluster: Dihydroorotase, multifunctional complex...    67   6e-10
UniRef50_Q8YUN6 Cluster: Dihydroorotase; n=4; Bacteria|Rep: Dihy...    66   1e-09
UniRef50_Q0W790 Cluster: Dihydroorotase; n=1; uncultured methano...    65   2e-09
UniRef50_UPI0000DAE5C6 Cluster: hypothetical protein Rgryl_01000...    64   3e-09
UniRef50_Q4JN07 Cluster: Dihydroorotase; n=3; Bacteria|Rep: Dihy...    64   4e-09
UniRef50_Q58885 Cluster: Dihydroorotase; n=6; Methanococcales|Re...    63   7e-09
UniRef50_Q7NF57 Cluster: Dihydroorotase; n=12; Cyanobacteria|Rep...    63   1e-08
UniRef50_Q8ZZC7 Cluster: Dihydroorotase; n=4; Pyrobaculum|Rep: D...    62   1e-08
UniRef50_O28034 Cluster: Dihydroorotase; n=1; Archaeoglobus fulg...    61   3e-08
UniRef50_A0B872 Cluster: Dihydroorotase, multifunctional complex...    61   4e-08
UniRef50_Q9HMH9 Cluster: Dihydroorotase; n=6; Halobacteriaceae|R...    60   7e-08
UniRef50_Q2FLR3 Cluster: Dihydroorotase; n=3; Methanomicrobiales...    59   1e-07
UniRef50_P77884 Cluster: Dihydroorotase; n=25; Bacilli|Rep: Dihy...    58   3e-07
UniRef50_Q30X37 Cluster: Dihydroorotase, multifunctional complex...    58   4e-07
UniRef50_A3ZRV3 Cluster: Dihydroorotase; n=1; Blastopirellula ma...    57   5e-07
UniRef50_Q28JR7 Cluster: Allantoinase; n=1; Jannaschia sp. CCS1|...    57   6e-07
UniRef50_Q2NHZ6 Cluster: Dihydroorotase; n=1; Methanosphaera sta...    57   6e-07
UniRef50_Q5HGN1 Cluster: Dihydroorotase; n=14; Bacillales|Rep: D...    57   6e-07
UniRef50_A5ULX4 Cluster: Dihydroorotase, PyrC; n=1; Methanobrevi...    56   8e-07
UniRef50_A5UX77 Cluster: Dihydroorotase, multifunctional complex...    56   1e-06
UniRef50_Q984Y5 Cluster: Dihydroorotase; n=50; cellular organism...    56   1e-06
UniRef50_Q73ID8 Cluster: Dihydroorotase; n=15; Rickettsiales|Rep...    55   2e-06
UniRef50_Q5FPJ5 Cluster: Dihydroorotase; n=4; Proteobacteria|Rep...    55   2e-06
UniRef50_Q4QEW1 Cluster: Dihydroorotase, putative; n=9; Trypanos...    55   2e-06
UniRef50_Q74DP4 Cluster: Dihydroorotase, multifunctional complex...    55   3e-06
UniRef50_P25995 Cluster: Dihydroorotase; n=41; Bacteria|Rep: Dih...    55   3e-06
UniRef50_Q9PEP0 Cluster: Dihydroorotase; n=54; cellular organism...    54   3e-06
UniRef50_Q3AC01 Cluster: Dihydroorotase; n=1; Carboxydothermus h...    54   3e-06
UniRef50_Q2RGZ6 Cluster: D-hydantoinase; n=1; Moorella thermoace...    54   4e-06
UniRef50_P07259 Cluster: Protein URA1 [Includes: Glutamine-depen...    54   4e-06
UniRef50_Q0LDY3 Cluster: Dihydroorotase; n=2; Chloroflexi (class...    54   6e-06
UniRef50_A4GJR5 Cluster: Dihydroorotase; n=6; Bacteria|Rep: Dihy...    54   6e-06
UniRef50_A4ECL5 Cluster: Dihydroorotase; n=1; Collinsella aerofa...    54   6e-06
UniRef50_Q8XL61 Cluster: Dihydroorotase; n=12; Bacteria|Rep: Dih...    53   8e-06
UniRef50_Q89PZ7 Cluster: D-hydantoinase; n=5; Alphaproteobacteri...    53   8e-06
UniRef50_Q6U5R7 Cluster: PyrC; n=6; Gammaproteobacteria|Rep: Pyr...    53   8e-06
UniRef50_Q1VNG2 Cluster: Dihydroorotase; n=2; Psychroflexus torq...    53   8e-06
UniRef50_A5NZP0 Cluster: Dihydropyrimidinase; n=5; Proteobacteri...    53   8e-06
UniRef50_Q7NEQ6 Cluster: Dihydroorotase; n=1; Gloeobacter violac...    53   1e-05
UniRef50_Q8KDK5 Cluster: Dihydroorotase; n=10; Chlorobiaceae|Rep...    53   1e-05
UniRef50_Q9KAH8 Cluster: Allantoinase; n=1; Bacillus halodurans|...    52   1e-05
UniRef50_Q8AB61 Cluster: Dihydroorotase; n=3; Bacteroides|Rep: D...    52   1e-05
UniRef50_Q2KXE6 Cluster: D-hydantoinase; n=2; Proteobacteria|Rep...    52   1e-05
UniRef50_A4XKT2 Cluster: Dihydroorotase, multifunctional complex...    52   1e-05
UniRef50_O27199 Cluster: Dihydroorotase; n=2; Methanothermobacte...    52   1e-05
UniRef50_Q0UHH4 Cluster: Putative uncharacterized protein; n=1; ...    52   2e-05
UniRef50_O66990 Cluster: Dihydroorotase; n=1; Aquifex aeolicus|R...    52   2e-05
UniRef50_A6TVS5 Cluster: Dihydroorotase; n=8; Clostridiales|Rep:...    51   3e-05
UniRef50_A7D6W5 Cluster: Amidohydrolase; n=1; Halorubrum lacuspr...    51   3e-05
UniRef50_A5DGE8 Cluster: Putative uncharacterized protein; n=1; ...    51   4e-05
UniRef50_Q6AF87 Cluster: Dihydroorotase; n=9; Actinobacteria (cl...    51   4e-05
UniRef50_Q1M4X9 Cluster: Putative D-hydantoinase; n=1; Rhizobium...    50   6e-05
UniRef50_Q18ZN3 Cluster: Dihydroorotase; n=3; Clostridiales|Rep:...    50   6e-05
UniRef50_Q9RVC3 Cluster: Dihydroorotase; n=5; Deinococci|Rep: Di...    50   6e-05
UniRef50_Q3AEA1 Cluster: Allantoinase; n=3; Clostridiales|Rep: A...    50   7e-05
UniRef50_A6P0Z6 Cluster: Dihydroorotase; n=1; Bacteroides capill...    50   7e-05
UniRef50_A3H6L5 Cluster: Amidohydrolase; n=1; Caldivirga maquili...    50   7e-05
UniRef50_Q8R9R6 Cluster: Dihydroorotase; n=5; Clostridia|Rep: Di...    50   7e-05
UniRef50_A7CWA7 Cluster: Dihydroorotase, multifunctional complex...    50   1e-04
UniRef50_Q97LN7 Cluster: Dihydroorotase; n=4; Clostridiales|Rep:...    50   1e-04
UniRef50_A4GK51 Cluster: Dihydroorotase; n=1; uncultured marine ...    49   1e-04
UniRef50_A0RQX7 Cluster: Dihydroorotase; n=4; Campylobacter|Rep:...    49   1e-04
UniRef50_UPI00015BB20A Cluster: dihydroorotase; n=1; Ignicoccus ...    49   2e-04
UniRef50_Q8F061 Cluster: Dihydroorotase; n=5; Bacteria|Rep: Dihy...    49   2e-04
UniRef50_Q83HU2 Cluster: Dihydroorotase; n=2; Tropheryma whipple...    49   2e-04
UniRef50_Q765R4 Cluster: Allantoinase; n=1; Klebsiella pneumonia...    49   2e-04
UniRef50_Q18S75 Cluster: Amidohydrolase; n=2; Desulfitobacterium...    49   2e-04
UniRef50_A6R6Y6 Cluster: Allantoinase; n=1; Ajellomyces capsulat...    49   2e-04
UniRef50_Q97QN4 Cluster: Dihydroorotase; n=47; Firmicutes|Rep: D...    49   2e-04
UniRef50_Q8TSA6 Cluster: Dihydroorotase; n=4; Methanosarcinaceae...    49   2e-04
UniRef50_Q64RK7 Cluster: Dihydroorotase; n=6; Bacteroidales|Rep:...    48   2e-04
UniRef50_Q1M4Y4 Cluster: Putative dihydroorotase; n=1; Rhizobium...    48   2e-04
UniRef50_A5ZPT0 Cluster: Dihydroorotase; n=1; Ruminococcus obeum...    48   2e-04
UniRef50_Q44184 Cluster: D-hydantoinase; n=5; Proteobacteria|Rep...    48   2e-04
UniRef50_Q1Q402 Cluster: Similar to dihydroorotase; n=1; Candida...    48   3e-04
UniRef50_P77671 Cluster: Allantoinase; n=25; Bacteria|Rep: Allan...    48   4e-04
UniRef50_A5NXH5 Cluster: Allantoinase; n=2; Proteobacteria|Rep: ...    47   5e-04
UniRef50_A0L3T8 Cluster: Dihydroorotase, multifunctional complex...    47   7e-04
UniRef50_P81006 Cluster: Non-ATP-dependent L-selective hydantoin...    47   7e-04
UniRef50_O69809 Cluster: D-hydantoinase; n=4; Bacteria|Rep: D-hy...    47   7e-04
UniRef50_O32137 Cluster: Allantoinase; n=1; Bacillus subtilis|Re...    47   7e-04
UniRef50_Q831D1 Cluster: D-hydantoinase; n=6; Firmicutes|Rep: D-...    46   9e-04
UniRef50_A4M847 Cluster: Dihydropyrimidinase; n=1; Petrotoga mob...    46   9e-04
UniRef50_Q6A916 Cluster: Dihydroorotase; n=1; Propionibacterium ...    46   0.001
UniRef50_Q3ZYB9 Cluster: Dihydroorotase, multifunctional complex...    46   0.001
UniRef50_A7HCE8 Cluster: Dihydroorotase, multifunctional complex...    46   0.001
UniRef50_A4AEE1 Cluster: Dihydroorotase and related cyclic amido...    46   0.001
UniRef50_A2R282 Cluster: Contig An13c0120, complete genome; n=3;...    46   0.001
UniRef50_A3DKS9 Cluster: Amidohydrolase; n=1; Staphylothermus ma...    46   0.001
UniRef50_Q2JER9 Cluster: Allantoinase; n=5; Bacteria|Rep: Allant...    46   0.002
UniRef50_A6LUT2 Cluster: Dihydropyrimidinase; n=3; cellular orga...    46   0.002
UniRef50_Q9RKU5 Cluster: Probable allantoinase; n=8; Actinomycet...    46   0.002
UniRef50_UPI0001597BA8 Cluster: PucH; n=1; Bacillus amyloliquefa...    45   0.002
UniRef50_Q67Q00 Cluster: Dihydroorotase; n=6; Bacteria|Rep: Dihy...    45   0.002
UniRef50_A3ESI6 Cluster: Dihydroorotase; n=3; Bacteria|Rep: Dihy...    45   0.002
UniRef50_A1SH63 Cluster: Dihydropyrimidinase; n=1; Nocardioides ...    45   0.002
UniRef50_UPI00015BD532 Cluster: UPI00015BD532 related cluster; n...    45   0.003
UniRef50_Q89Q35 Cluster: D-hydantoinase; n=20; Proteobacteria|Re...    45   0.003
UniRef50_A6E6Y3 Cluster: Dihydroorotase; n=1; Pedobacter sp. BAL...    45   0.003
UniRef50_Q5KFL1 Cluster: Dihydropyrimidinase, putative; n=2; Fil...    45   0.003
UniRef50_UPI000038E4AB Cluster: hypothetical protein Faci_030004...    44   0.004
UniRef50_Q89K18 Cluster: Blr5100 protein; n=43; Alphaproteobacte...    44   0.004
UniRef50_A6PU21 Cluster: Dihydroorotase, multifunctional complex...    44   0.004
UniRef50_Q8NQ39 Cluster: Dihydroorotase; n=35; Actinomycetales|R...    44   0.004
UniRef50_Q1IJ01 Cluster: Dihydroorotase, multifunctional complex...    44   0.005
UniRef50_Q18WQ5 Cluster: Dihydroorotase, multifunctional complex...    44   0.005
UniRef50_A2U746 Cluster: Dihydropyrimidinase; n=3; Bacillus|Rep:...    44   0.005
UniRef50_Q9P903 Cluster: Dihydropyrimidinase; n=2; Saccharomycet...    44   0.005
UniRef50_A3LNF2 Cluster: Allantoinase; n=2; Saccharomycetales|Re...    44   0.005
UniRef50_A1C896 Cluster: Aminohydrolase; n=6; cellular organisms...    44   0.005
UniRef50_Q73KW0 Cluster: Dihydroorotase, putative; n=1; Treponem...    44   0.006
UniRef50_A5DY43 Cluster: Putative uncharacterized protein; n=1; ...    44   0.006
UniRef50_Q1VPD0 Cluster: Dihydroorotase; n=11; Bacteroidetes|Rep...    43   0.008
UniRef50_Q9RV76 Cluster: Probable allantoinase; n=4; Bacteria|Re...    43   0.008
UniRef50_Q2SMZ8 Cluster: Dihydroorotase and related cyclic amido...    43   0.011
UniRef50_A4EA66 Cluster: Putative uncharacterized protein; n=1; ...    43   0.011
UniRef50_A4C048 Cluster: Amidohydrolase family, putative; n=10; ...    43   0.011
UniRef50_Q64E81 Cluster: Dihydroorotase; n=1; uncultured archaeo...    43   0.011
UniRef50_A0RTM1 Cluster: Dihydroorotase; n=2; Thermoprotei|Rep: ...    43   0.011
UniRef50_Q51551 Cluster: Dihydroorotase-like protein; n=14; Gamm...    43   0.011
UniRef50_Q9WYH0 Cluster: Dihydroorotase; n=4; Thermotogaceae|Rep...    43   0.011
UniRef50_Q8YRV3 Cluster: Dihydroorotase; n=8; Cyanobacteria|Rep:...    42   0.015
UniRef50_Q5FRG9 Cluster: Dihydroorotase; n=4; Rhodospirillales|R...    42   0.015
UniRef50_A7B6D5 Cluster: Putative uncharacterized protein; n=1; ...    42   0.015
UniRef50_Q4AGB4 Cluster: Dihydropyrimidinase; n=1; Chlorobium ph...    42   0.025
UniRef50_Q6CUK0 Cluster: Similar to sp|P32375 Saccharomyces cere...    42   0.025
UniRef50_A1CFB0 Cluster: Allantoinase Dal1, putative; n=11; Pezi...    42   0.025
UniRef50_A2BJ21 Cluster: Dihydroorotase; n=1; Hyperthermus butyl...    42   0.025
UniRef50_Q2S0H8 Cluster: Dihydroorotase; n=1; Salinibacter ruber...    41   0.034
UniRef50_Q26E93 Cluster: Dihydroorotase; n=1; Flavobacteria bact...    41   0.034
UniRef50_Q9UX05 Cluster: Dihydroorotase; n=5; Sulfolobaceae|Rep:...    41   0.034
UniRef50_Q930B0 Cluster: Allantoinase, putative; n=1; Sinorhizob...    41   0.045
UniRef50_A6DRU9 Cluster: Dihydroorotase; n=1; Lentisphaera arane...    41   0.045
UniRef50_Q6C0N2 Cluster: Similar to sp|P32375 Saccharomyces cere...    41   0.045
UniRef50_Q8TXX9 Cluster: Dihydroorotase; n=1; Methanopyrus kandl...    41   0.045
UniRef50_Q1AVY7 Cluster: Dihydroorotase; n=1; Rubrobacter xylano...    40   0.059
UniRef50_Q4FLQ3 Cluster: Dihydroorotase; n=2; Candidatus Pelagib...    40   0.078
UniRef50_Q18S74 Cluster: Amidohydrolase; n=2; Desulfitobacterium...    40   0.078
UniRef50_A6CS57 Cluster: Dihydropyrimidinase; n=1; Bacillus sp. ...    40   0.078
UniRef50_Q6KZ43 Cluster: Dihydroorotase; n=2; Thermoplasmatales|...    40   0.078
UniRef50_Q2JMN8 Cluster: Dihydroorotase, putative; n=2; Synechoc...    39   0.14 
UniRef50_Q24PA5 Cluster: Putative uncharacterized protein; n=1; ...    39   0.14 
UniRef50_Q6BV31 Cluster: Similar to CA5801|CaDAL1 Candida albica...    39   0.14 
UniRef50_P40757 Cluster: Allantoinase, mitochondrial precursor; ...    39   0.14 
UniRef50_Q84FR6 Cluster: D-hydantoinase; n=1; Arthrobacter cryst...    39   0.18 
UniRef50_A6CCA9 Cluster: Dihydroorotase, multifunctional complex...    39   0.18 
UniRef50_Q972W9 Cluster: 413aa long hypothetical D-hydantoinase;...    39   0.18 
UniRef50_P32375 Cluster: Allantoinase; n=3; Saccharomycetaceae|R...    39   0.18 
UniRef50_Q5NPE4 Cluster: Dihydroorotase; n=8; Sphingomonadales|R...    38   0.24 
UniRef50_Q31EK1 Cluster: Aspartate carbamoyltransferase, non-cat...    38   0.24 
UniRef50_A1A2Z8 Cluster: Putative allantoinase; n=3; Bifidobacte...    38   0.24 
UniRef50_Q2GR02 Cluster: Putative uncharacterized protein; n=4; ...    38   0.24 
UniRef50_Q31R01 Cluster: Dihydroorotase and related cyclic amido...    38   0.31 
UniRef50_A5KJ64 Cluster: Putative uncharacterized protein; n=1; ...    38   0.31 
UniRef50_Q259B7 Cluster: H0901F07.3 protein; n=12; Magnoliophyta...    38   0.31 
UniRef50_Q5PR45 Cluster: Zgc:103559; n=8; Eumetazoa|Rep: Zgc:103...    38   0.41 
UniRef50_Q8EW20 Cluster: Dihydroorotase; n=1; Mycoplasma penetra...    38   0.41 
UniRef50_A3DM45 Cluster: Amidohydrolase; n=1; Staphylothermus ma...    38   0.41 
UniRef50_Q8G657 Cluster: Dihydroorotase; n=4; Bifidobacterium|Re...    37   0.55 
UniRef50_A6NQ76 Cluster: Putative uncharacterized protein; n=1; ...    37   0.55 
UniRef50_A6G7W0 Cluster: Dihydroorotase and related cyclic amido...    37   0.55 
UniRef50_Q9YFI5 Cluster: Dihydroorotase; n=1; Aeropyrum pernix|R...    37   0.55 
UniRef50_Q30S48 Cluster: Amidohydrolase; n=1; Thiomicrospira den...    37   0.72 
UniRef50_Q08M50 Cluster: Allantoinase; n=1; Stigmatella aurantia...    37   0.72 
UniRef50_A5ZUT5 Cluster: Putative uncharacterized protein; n=1; ...    37   0.72 
UniRef50_Q1ERB5 Cluster: L-hydantoinase HyuH; n=1; uncultured cr...    37   0.72 
UniRef50_Q2KUT6 Cluster: Dihydroorotase precursor; n=1; Bordetel...    36   0.96 
UniRef50_A6LUW0 Cluster: Dihydropyrimidinase; n=1; Clostridium b...    36   0.96 
UniRef50_Q97C35 Cluster: Dihydroorotase; n=2; Thermoplasma|Rep: ...    36   0.96 
UniRef50_Q4T977 Cluster: Chromosome undetermined SCAF7631, whole...    36   1.3  
UniRef50_Q7WMP7 Cluster: Dihydroorotase-like protein; n=3; Borde...    36   1.3  
UniRef50_Q47RB7 Cluster: Allantoinase; n=1; Thermobifida fusca Y...    36   1.3  
UniRef50_A4CLI6 Cluster: Dihydroorotase, multifunctional complex...    36   1.3  
UniRef50_A0K2C1 Cluster: Dihydropyrimidinase; n=1; Arthrobacter ...    36   1.3  
UniRef50_Q972L4 Cluster: 464aa long hypothetical D-hydantoinase;...    36   1.3  
UniRef50_Q7UNR2 Cluster: Putative dihydroorotase; n=1; Pirellula...    36   1.3  
UniRef50_Q59699 Cluster: D-hydantoinase; n=11; Proteobacteria|Re...    36   1.3  
UniRef50_Q1AZI1 Cluster: D-hydantoinase; n=1; Rubrobacter xylano...    36   1.7  
UniRef50_Q0VTM6 Cluster: Dihydroorotase, multifunctional complex...    36   1.7  
UniRef50_A6VSQ0 Cluster: Dihydroorotase, multifunctional complex...    36   1.7  
UniRef50_A3HYA6 Cluster: Dihydroorotase and related cyclic amido...    36   1.7  
UniRef50_A4R534 Cluster: Putative uncharacterized protein; n=1; ...    36   1.7  
UniRef50_Q972X8 Cluster: 433aa long hypothetical D-hydantoinase;...    36   1.7  
UniRef50_Q45515 Cluster: D-hydantoinase; n=14; Bacteria|Rep: D-h...    36   1.7  
UniRef50_UPI00015B49FE Cluster: PREDICTED: similar to alpha-gluc...    35   2.2  
UniRef50_A6WFZ1 Cluster: Dihydropyrimidinase; n=1; Kineococcus r...    35   2.2  
UniRef50_A5GXS3 Cluster: Faciata 1-like protein; n=6; Poaceae|Re...    35   2.2  
UniRef50_Q2LWS0 Cluster: DNA polymerase III, delta subunit; n=1;...    35   2.9  
UniRef50_A3PPE1 Cluster: Dihydropyrimidinase; n=3; Rhodobacter s...    35   2.9  
UniRef50_Q7JZT9 Cluster: RE13129p; n=5; Diptera|Rep: RE13129p - ...    35   2.9  
UniRef50_Q11EY4 Cluster: Dihydropyrimidinase; n=25; Proteobacter...    34   3.9  
UniRef50_Q0BZU5 Cluster: Putative dihydroorotase; n=1; Hyphomona...    34   3.9  
UniRef50_A3UJX0 Cluster: Aspartate transcarbamoylase, pyrC' subu...    34   3.9  
UniRef50_UPI0001554813 Cluster: PREDICTED: hypothetical protein;...    34   5.1  
UniRef50_Q12EE5 Cluster: Allantoinase; n=57; Betaproteobacteria|...    34   5.1  
UniRef50_A3ZYR8 Cluster: Dihydroorotase; n=1; Blastopirellula ma...    34   5.1  
UniRef50_Q18IV3 Cluster: Dihydroorotase; n=1; Haloquadratum wals...    34   5.1  
UniRef50_Q8YF78 Cluster: D-HYDANTOINASE; n=41; Proteobacteria|Re...    33   6.8  
UniRef50_P72934 Cluster: Probable dihydroorotase-like protein; n...    33   6.8  

>UniRef50_Q1RKZ5 Cluster: IP15551p; n=1; Drosophila
           melanogaster|Rep: IP15551p - Drosophila melanogaster
           (Fruit fly)
          Length = 746

 Score =  145 bits (352), Expect = 1e-33
 Identities = 64/107 (59%), Positives = 79/107 (73%)
 Frame = -2

Query: 557 SASCSSKDVLK*NFYNFLLEDMTIWQKHFQSWPKKMPVCTHAEREKTAAVILMASLLDRP 378
           S +C  K  L   F    L DMT WQ+H   WPK+ P+  HAER+ TAAVI++A LLDR 
Sbjct: 331 SHACGLKMYLNDTFGTLKLSDMTSWQRHLSHWPKRSPIVCHAERQSTAAVIMLAHLLDRS 390

Query: 377 VHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDITKLEKG 237
           VHICHVARKEEI +I++AKE+GVKVTCEVCPHHLFL++ D+ +L  G
Sbjct: 391 VHICHVARKEEIQLIRSAKEKGVKVTCEVCPHHLFLSTKDVERLGHG 437



 Score =  122 bits (294), Expect = 1e-26
 Identities = 63/106 (59%), Positives = 71/106 (66%)
 Frame = -3

Query: 826 IVKLPGFIDVHVHVREPGANIKGRF*DLLPQXHWLVVLTMICAMPNTNPSIVDRTAFDYA 647
           IVKLPGFIDVHVH+REPGA  K  F            +T++CAMPNTNPSIVDR  F   
Sbjct: 242 IVKLPGFIDVHVHLREPGATHKEDFASGTAAA-LAGGVTLVCAMPNTNPSIVDRETFTQF 300

Query: 646 STLARVSARCDYALYVGASSTNYDTICELAPQAAALKMYLNETFTT 509
             LA+  ARCDYALYVGAS  N+  + ELA  A  LKMYLN+TF T
Sbjct: 301 QELAKAGARCDYALYVGASDDNWAQVNELASHACGLKMYLNDTFGT 346



 Score = 37.9 bits (84), Expect = 0.31
 Identities = 14/25 (56%), Positives = 19/25 (76%)
 Frame = -1

Query: 252 KIGKGRAKVCPVLCSPEDQAELWRN 178
           ++G G ++V P+LCSPEDQ  LW N
Sbjct: 433 RLGHGMSEVRPLLCSPEDQEALWEN 457


>UniRef50_P05990 Cluster: CAD protein (Protein rudimentary) [Includes:
            Glutamine-dependent carbamoyl-phosphate synthase (EC
            6.3.5.5); Aspartate carbamoyltransferase (EC 2.1.3.2);
            Dihydroorotase (EC 3.5.2.3)]; n=206; cellular
            organisms|Rep: CAD protein (Protein rudimentary)
            [Includes: Glutamine-dependent carbamoyl-phosphate
            synthase (EC 6.3.5.5); Aspartate carbamoyltransferase (EC
            2.1.3.2); Dihydroorotase (EC 3.5.2.3)] - Drosophila
            melanogaster (Fruit fly)
          Length = 2224

 Score =  145 bits (352), Expect = 1e-33
 Identities = 64/107 (59%), Positives = 79/107 (73%)
 Frame = -2

Query: 557  SASCSSKDVLK*NFYNFLLEDMTIWQKHFQSWPKKMPVCTHAEREKTAAVILMASLLDRP 378
            S +C  K  L   F    L DMT WQ+H   WPK+ P+  HAER+ TAAVI++A LLDR 
Sbjct: 1565 SHACGLKMYLNDTFGTLKLSDMTSWQRHLSHWPKRSPIVCHAERQSTAAVIMLAHLLDRS 1624

Query: 377  VHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDITKLEKG 237
            VHICHVARKEEI +I++AKE+GVKVTCEVCPHHLFL++ D+ +L  G
Sbjct: 1625 VHICHVARKEEIQLIRSAKEKGVKVTCEVCPHHLFLSTKDVERLGHG 1671



 Score =  127 bits (306), Expect = 4e-28
 Identities = 54/77 (70%), Positives = 65/77 (84%)
 Frame = -1

Query: 252  KIGKGRAKVCPVLCSPEDQAELWRNISIIDVFATDHAPHTVEEKNSENPPPGYPGLETIL 73
            ++G G ++V P+LCSPEDQ  LW NI  IDVFATDHAPHT+ EK SE PPPG+PG+ETIL
Sbjct: 1667 RLGHGMSEVRPLLCSPEDQEALWENIDYIDVFATDHAPHTLAEKRSERPPPGFPGVETIL 1726

Query: 72   PLLLNAVHQGRLTIEDL 22
            PLLL AVH+GRLT+ED+
Sbjct: 1727 PLLLQAVHEGRLTMEDI 1743



 Score =  122 bits (294), Expect = 1e-26
 Identities = 63/106 (59%), Positives = 71/106 (66%)
 Frame = -3

Query: 826  IVKLPGFIDVHVHVREPGANIKGRF*DLLPQXHWLVVLTMICAMPNTNPSIVDRTAFDYA 647
            IVKLPGFIDVHVH+REPGA  K  F            +T++CAMPNTNPSIVDR  F   
Sbjct: 1476 IVKLPGFIDVHVHLREPGATHKEDFASGTAAA-LAGGVTLVCAMPNTNPSIVDRETFTQF 1534

Query: 646  STLARVSARCDYALYVGASSTNYDTICELAPQAAALKMYLNETFTT 509
              LA+  ARCDYALYVGAS  N+  + ELA  A  LKMYLN+TF T
Sbjct: 1535 QELAKAGARCDYALYVGASDDNWAQVNELASHACGLKMYLNDTFGT 1580


>UniRef50_A7T4N0 Cluster: Predicted protein; n=1; Nematostella
            vectensis|Rep: Predicted protein - Nematostella vectensis
          Length = 1362

 Score =  129 bits (312), Expect = 7e-29
 Identities = 55/98 (56%), Positives = 71/98 (72%)
 Frame = -2

Query: 539  KDVLK*NFYNFLLEDMTIWQKHFQSWPKKMPVCTHAEREKTAAVILMASLLDRPVHICHV 360
            K  L   F    L+D+TIW KH ++WP  MP+  HAE   TAA++L+A L DRPVHI HV
Sbjct: 992  KMYLNETFTTLRLDDLTIWMKHLENWPLHMPIVCHAEGRTTAAILLLAELADRPVHIAHV 1051

Query: 359  ARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDITKL 246
            ARKEEI++I+AAKERG+ VTCEV PHHLF+  +D  ++
Sbjct: 1052 ARKEEIMVIRAAKERGLAVTCEVAPHHLFMTKDDAARI 1089



 Score =  119 bits (286), Expect = 1e-25
 Identities = 54/81 (66%), Positives = 64/81 (79%)
 Frame = -1

Query: 252  KIGKGRAKVCPVLCSPEDQAELWRNISIIDVFATDHAPHTVEEKNSENPPPGYPGLETIL 73
            +IG+   +V P L + EDQ  LW N+  ID FATDHAPHT+EEKNS N PPG+PGLET+L
Sbjct: 1088 RIGESWIRVKPPLVTAEDQMALWDNMEYIDCFATDHAPHTIEEKNSTNSPPGFPGLETML 1147

Query: 72   PLLLNAVHQGRLTIEDLLCRI 10
            PLLL AVHQGRLTIEDL+ R+
Sbjct: 1148 PLLLTAVHQGRLTIEDLVKRL 1168



 Score =  117 bits (281), Expect = 4e-25
 Identities = 59/106 (55%), Positives = 71/106 (66%)
 Frame = -3

Query: 826  IVKLPGFIDVHVHVREPGANIKGRF*DLLPQXHWLVVLTMICAMPNTNPSIVDRTAFDYA 647
            IV+LPG IDVHVH+REPGA  K  F            +TM+ AMPNTNP +VD  +F+ A
Sbjct: 897  IVRLPGLIDVHVHLREPGATHKEDFASGTAAA-LAGGITMVLAMPNTNPPLVDEESFNLA 955

Query: 646  STLARVSARCDYALYVGASSTNYDTICELAPQAAALKMYLNETFTT 509
              L    ARCDYALY+GA  TNY  + ++A +AA LKMYLNETFTT
Sbjct: 956  KKLGTAGARCDYALYLGAGPTNYTMLKDIAHRAAGLKMYLNETFTT 1001


>UniRef50_P27708 Cluster: CAD protein [Includes: Glutamine-dependent
            carbamoyl-phosphate synthase (EC 6.3.5.5); Aspartate
            carbamoyltransferase (EC 2.1.3.2); Dihydroorotase (EC
            3.5.2.3)]; n=277; cellular organisms|Rep: CAD protein
            [Includes: Glutamine-dependent carbamoyl-phosphate
            synthase (EC 6.3.5.5); Aspartate carbamoyltransferase (EC
            2.1.3.2); Dihydroorotase (EC 3.5.2.3)] - Homo sapiens
            (Human)
          Length = 2225

 Score =  123 bits (297), Expect = 5e-27
 Identities = 56/109 (51%), Positives = 76/109 (69%)
 Frame = -2

Query: 560  GSASCSSKDVLK*NFYNFLLEDMTIWQKHFQSWPKKMPVCTHAEREKTAAVILMASLLDR 381
            GSA+   K  L   F    L+ +  W +HF++WP  +P+  HAE++  AAV+++A L  R
Sbjct: 1550 GSAA-GLKLYLNETFSELRLDSVVQWMEHFETWPSHLPIVAHAEQQTVAAVLMVAQLTQR 1608

Query: 380  PVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDITKLEKGE 234
             VHICHVARKEEIL+IKAAK RG+ VTCEV PHHLFL+ +D+ +L  G+
Sbjct: 1609 SVHICHVARKEEILLIKAAKARGLPVTCEVAPHHLFLSHDDLERLGPGK 1657



 Score =  110 bits (264), Expect = 5e-23
 Identities = 47/83 (56%), Positives = 64/83 (77%)
 Frame = -1

Query: 252  KIGKGRAKVCPVLCSPEDQAELWRNISIIDVFATDHAPHTVEEKNSENPPPGYPGLETIL 73
            ++G G+ +V P L S +D   LW N+++ID FA+DHAPHT+EEK    PPPG+PGLET+L
Sbjct: 1652 RLGPGKGEVRPELGSRQDVEALWENMAVIDCFASDHAPHTLEEKCGSRPPPGFPGLETML 1711

Query: 72   PLLLNAVHQGRLTIEDLLCRIRH 4
            PLLL AV +GRL+++DLL R+ H
Sbjct: 1712 PLLLTAVSEGRLSLDDLLQRLHH 1734



 Score =  105 bits (253), Expect = 1e-21
 Identities = 54/105 (51%), Positives = 67/105 (63%)
 Frame = -3

Query: 826  IVKLPGFIDVHVHVREPGANIKGRF*DLLPQXHWLVVLTMICAMPNTNPSIVDRTAFDYA 647
            +V+LPG IDVHVH+REPG   K  F            +TM+CAMPNT P I+D  A   A
Sbjct: 1461 LVRLPGLIDVHVHLREPGGTHKEDFASGTAAA-LAGGITMVCAMPNTRPPIIDAPALALA 1519

Query: 646  STLARVSARCDYALYVGASSTNYDTICELAPQAAALKMYLNETFT 512
              LA   ARCD+AL++GASS N  T+  +A  AA LK+YLNETF+
Sbjct: 1520 QKLAEAGARCDFALFLGASSENAGTLGTVAGSAAGLKLYLNETFS 1564


>UniRef50_Q5RHG8 Cluster: Carbamoyl-phosphate synthetase 2, aspartate
            transcarbamylase, and dihydroorotase; n=23;
            Coelomata|Rep: Carbamoyl-phosphate synthetase 2,
            aspartate transcarbamylase, and dihydroorotase - Danio
            rerio (Zebrafish) (Brachydanio rerio)
          Length = 2154

 Score =  120 bits (290), Expect = 3e-26
 Identities = 49/84 (58%), Positives = 68/84 (80%)
 Frame = -2

Query: 491  TIWQKHFQSWPKKMPVCTHAEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERG 312
            T+ QKHF+ WPK +P+  HAE++  AA++L+A L  RPVHICHVA+KEEILII+AAK++G
Sbjct: 1523 TMAQKHFEKWPKHLPIVAHAEKQTVAAILLVAQLYQRPVHICHVAKKEEILIIRAAKQKG 1582

Query: 311  VKVTCEVCPHHLFLNSNDITKLEK 240
            ++VTCEV PHHLFL  +++  + K
Sbjct: 1583 IQVTCEVAPHHLFLCEDNVPVIGK 1606



 Score =  114 bits (274), Expect = 3e-24
 Identities = 50/80 (62%), Positives = 63/80 (78%)
 Frame = -1

Query: 249  IGKGRAKVCPVLCSPEDQAELWRNISIIDVFATDHAPHTVEEKNSENPPPGYPGLETILP 70
            IGK +A+V P+L + ED   LW N+ IID FATDHAPH+ EEK SE PPPGYPGLET+LP
Sbjct: 1604 IGKDKAQVRPMLGTREDMEALWENLDIIDCFATDHAPHSAEEKISEKPPPGYPGLETMLP 1663

Query: 69   LLLNAVHQGRLTIEDLLCRI 10
            LL  AV +GRLT++D++ R+
Sbjct: 1664 LLFTAVSEGRLTVDDIIKRL 1683



 Score = 62.1 bits (144), Expect = 2e-08
 Identities = 30/60 (50%), Positives = 39/60 (65%)
 Frame = -3

Query: 826  IVKLPGFIDVHVHVREPGANIKGRF*DLLPQXHWLVVLTMICAMPNTNPSIVDRTAFDYA 647
            +++LPG IDVHVH+REPGA  K  F            +TM+CAMPNTNP+I+D  +F  A
Sbjct: 1467 LIRLPGLIDVHVHLREPGATHKEDF-SSGTAAALAGGITMVCAMPNTNPAIIDPNSFTMA 1525


>UniRef50_Q4SZL4 Cluster: Chromosome 14 SCAF11586, whole genome
            shotgun sequence; n=2; cellular organisms|Rep: Chromosome
            14 SCAF11586, whole genome shotgun sequence - Tetraodon
            nigroviridis (Green puffer)
          Length = 2178

 Score =  120 bits (288), Expect = 6e-26
 Identities = 53/81 (65%), Positives = 66/81 (81%)
 Frame = -1

Query: 252  KIGKGRAKVCPVLCSPEDQAELWRNISIIDVFATDHAPHTVEEKNSENPPPGYPGLETIL 73
            +IG GRA+V P+L S ED   LW N+ IID FATDHAPH++EEKNS +PPPGYPGLET+L
Sbjct: 1573 EIGSGRAQVRPMLGSREDMEALWENLDIIDCFATDHAPHSLEEKNSGSPPPGYPGLETML 1632

Query: 72   PLLLNAVHQGRLTIEDLLCRI 10
            PLLL AV  GRLT++D++ R+
Sbjct: 1633 PLLLTAVSDGRLTLDDIIKRL 1653



 Score =  101 bits (241), Expect = 3e-20
 Identities = 50/126 (39%), Positives = 74/126 (58%), Gaps = 25/126 (19%)
 Frame = -2

Query: 539  KDVLK*NFYNFLLEDMTIWQKHFQSWPKKMPVCTHAEREKTAAVILMASLLDRPVHICHV 360
            K  L   F    ++++++W +HF+ WP+ MP+  HAE++  AA++++A L  RPVHICHV
Sbjct: 1452 KMYLNDTFSTLKMDNVSLWMEHFEMWPRHMPIVAHAEKQTVAAILMVAQLYQRPVHICHV 1511

Query: 359  ARKEE-------------------------ILIIKAAKERGVKVTCEVCPHHLFLNSNDI 255
            ARKEE                         I II+AAK +G++VTCEV PHHLFL  +D+
Sbjct: 1512 ARKEEVNPHLLLLYFTSLVTNISDVLFSSQISIIRAAKLKGIQVTCEVAPHHLFLCEDDV 1571

Query: 254  TKLEKG 237
             ++  G
Sbjct: 1572 VEIGSG 1577



 Score = 97.5 bits (232), Expect = 4e-19
 Identities = 55/118 (46%), Positives = 70/118 (59%), Gaps = 12/118 (10%)
 Frame = -3

Query: 826  IVKLPGFIDVHVHVREPGANIKGRF*DLLPQXHWLVVLTMICAMPNTNPSIVDRTAFDYA 647
            +V+LPG IDVHVH+REPGA  K  F            +TM+CAMPNT+PS+ D T     
Sbjct: 1345 LVRLPGLIDVHVHLREPGATHKEDF-SSGTAAALAGGVTMVCAMPNTSPSVTDPTTLALV 1403

Query: 646  ST------------LARVSARCDYALYVGASSTNYDTICELAPQAAALKMYLNETFTT 509
                          LA+  +RCDYALY+GA+S N   +  +A QA ALKMYLN+TF+T
Sbjct: 1404 QKEANREAACLGFQLAKAGSRCDYALYLGAASDNAAILPSIAGQAVALKMYLNDTFST 1461


>UniRef50_Q8U4A0 Cluster: Dihydroorotase; n=5; Thermococcaceae|Rep:
           Dihydroorotase - Pyrococcus furiosus
          Length = 414

 Score = 77.4 bits (182), Expect = 4e-13
 Identities = 37/71 (52%), Positives = 52/71 (73%)
 Frame = -1

Query: 231 KVCPVLCSPEDQAELWRNISIIDVFATDHAPHTVEEKNSENPPPGYPGLETILPLLLNAV 52
           KV P L S ED+  LW+NI  + V A+DHAPHT+E+K  E    G PGLET +PLLL+AV
Sbjct: 245 KVYPPLRSEEDRIALWKNIDKVPVIASDHAPHTLEDK--EAGAAGLPGLETEVPLLLDAV 302

Query: 51  HQGRLTIEDLL 19
           ++G +T++D++
Sbjct: 303 NKGLITLQDIV 313



 Score = 40.7 bits (91), Expect = 0.045
 Identities = 23/74 (31%), Positives = 37/74 (50%)
 Frame = -2

Query: 470 QSWPKKMPVCTHAEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEV 291
           Q +P++ P+   AE      VI       +P HICH++  + + ++     R   ++ EV
Sbjct: 172 QKYPERPPI---AEIRAIERVIEAVKTHKKPAHICHISTAKGLKLL--LDSRLEMLSFEV 226

Query: 290 CPHHLFLNSNDITK 249
            PHHLFL  +D  K
Sbjct: 227 TPHHLFLTRSDYDK 240



 Score = 39.1 bits (87), Expect = 0.14
 Identities = 25/73 (34%), Positives = 36/73 (49%)
 Frame = -3

Query: 823 VKLPGFIDVHVHVREPGANIKGRF*DLLPQXHWLVVLTMICAMPNTNPSIVDRTAFDYAS 644
           V LPG IDVHVH+R+   + K    +   +      +T++  MPNT P I+D        
Sbjct: 48  VILPGLIDVHVHLRDFEESYKESI-ESGTKAAVHGGITVVFDMPNTKPPIMDEKTLKLRE 106

Query: 643 TLARVSARCDYAL 605
            L +  +  DYAL
Sbjct: 107 HLFKRKSYADYAL 119


>UniRef50_A6RFE1 Cluster: Bifunctional pyrimidine biosynthesis protein
            pyrABCN; n=4; Fungi/Metazoa group|Rep: Bifunctional
            pyrimidine biosynthesis protein pyrABCN - Ajellomyces
            capsulatus NAm1
          Length = 2404

 Score = 75.4 bits (177), Expect = 2e-12
 Identities = 32/73 (43%), Positives = 51/73 (69%)
 Frame = -2

Query: 476  HFQSWPKKMPVCTHAEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTC 297
            HF SWP   P+ T A+    A+++L+ASL +R +H+  V  KE+I +I  +KE+G+KVTC
Sbjct: 1796 HFASWPTNKPIITDAKATDLASILLLASLHNRNIHVMSVTSKEDIGLIALSKEKGLKVTC 1855

Query: 296  EVCPHHLFLNSND 258
            +V  + LFL+++D
Sbjct: 1856 DVAIYSLFLSTDD 1868



 Score = 52.8 bits (121), Expect = 1e-05
 Identities = 28/72 (38%), Positives = 40/72 (55%)
 Frame = -1

Query: 225  CPVLCSPEDQAELWRNISIIDVFATDHAPHTVEEKNSENPPPGYPGLETILPLLLNAVHQ 46
            C  L S +DQ  LW ++  ID+F+    P+ V  KN+    P   G++  LPLL  AV  
Sbjct: 1872 CACLPSKKDQEALWEHLDSIDIFSIGSLPYQVAGKNAS---PAV-GIQDALPLLFTAVSD 1927

Query: 45   GRLTIEDLLCRI 10
             RLT+ED+  R+
Sbjct: 1928 KRLTVEDITSRL 1939


>UniRef50_A2SQD3 Cluster: Dihydroorotase, multifunctional complex
           type; n=1; Methanocorpusculum labreanum Z|Rep:
           Dihydroorotase, multifunctional complex type -
           Methanocorpusculum labreanum (strain ATCC 43576 / DSM
           4855 / Z)
          Length = 421

 Score = 70.1 bits (164), Expect = 6e-11
 Identities = 34/74 (45%), Positives = 52/74 (70%), Gaps = 3/74 (4%)
 Frame = -1

Query: 231 KVCPVLCSPEDQAELWRNISIIDVFATDHAPHTVEEKN---SENPPPGYPGLETILPLLL 61
           K+ P L S +++  L +N + I V A+DHAPHT++EK+   S + P G PG+ET+LPLL+
Sbjct: 254 KMNPPLRSKKERLHLIQNFAKIPVIASDHAPHTIQEKSQPFSASAPSGVPGVETMLPLLM 313

Query: 60  NAVHQGRLTIEDLL 19
           NAV Q  +T+ D++
Sbjct: 314 NAVTQRTITLNDVI 327


>UniRef50_A1RZC7 Cluster: Dihydroorotase, multifunctional complex
           type; n=1; Thermofilum pendens Hrk 5|Rep:
           Dihydroorotase, multifunctional complex type -
           Thermofilum pendens (strain Hrk 5)
          Length = 431

 Score = 66.9 bits (156), Expect = 6e-10
 Identities = 34/70 (48%), Positives = 46/70 (65%), Gaps = 2/70 (2%)
 Frame = -1

Query: 234 AKVCPVLCSPEDQAELWRNIS--IIDVFATDHAPHTVEEKNSENPPPGYPGLETILPLLL 61
           AKV P L    D++ ++  ++  + D   TDHAPH+ EEK SE+PPPG+PGLE  L LLL
Sbjct: 265 AKVNPPLRGEADRSAVYSALARGLPDALVTDHAPHSPEEKASEDPPPGFPGLELALHLLL 324

Query: 60  NAVHQGRLTI 31
           + V  GRL +
Sbjct: 325 SEVLAGRLPL 334



 Score = 39.9 bits (89), Expect = 0.078
 Identities = 33/106 (31%), Positives = 44/106 (41%), Gaps = 4/106 (3%)
 Frame = -3

Query: 817 LPGFIDVHVHVREPGANIKGRF*DLLPQXHWLVV--LTMICAMPNTNPSIVDRTAFDYAS 644
           LPG +D+HVH+REPG   K    D        V   +T +  MPN  P     T    A 
Sbjct: 56  LPGMVDIHVHMREPGQEYKE---DWRTGSRAAVKGGVTFVADMPNNKPPA--NTCERLAE 110

Query: 643 TLARVSAR--CDYALYVGASSTNYDTICELAPQAAALKMYLNETFT 512
            L R   +   D+A Y G S  N + +          K+Y  E F+
Sbjct: 111 KLRRAGEKSLVDFAFYAGFSE-NPEELLRCPELFVGGKLYPEELFS 155



 Score = 33.9 bits (74), Expect = 5.1
 Identities = 14/39 (35%), Positives = 22/39 (56%)
 Frame = -2

Query: 377 VHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSN 261
           VH+ HV+    +  + +AK  G+K T +V PHH  L  +
Sbjct: 217 VHVTHVSTGAAVTELLSAKLSGLKATFDVTPHHALLTDS 255


>UniRef50_Q8YUN6 Cluster: Dihydroorotase; n=4; Bacteria|Rep:
           Dihydroorotase - Anabaena sp. (strain PCC 7120)
          Length = 439

 Score = 65.7 bits (153), Expect = 1e-09
 Identities = 34/72 (47%), Positives = 45/72 (62%), Gaps = 4/72 (5%)
 Frame = -1

Query: 234 AKVCPVLCSPEDQAELWRNI--SIIDVFATDHAPHTVEEKNS--ENPPPGYPGLETILPL 67
           A++ P L SP D   LW+ +   +ID  ATDHAPHT+EEK     N P G PG+ET L +
Sbjct: 275 AQMNPPLRSPHDNEVLWQALRDGVIDFIATDHAPHTLEEKAQPYPNSPSGMPGVETSLAV 334

Query: 66  LLNAVHQGRLTI 31
           +L A  +G+ TI
Sbjct: 335 MLTAAMEGKCTI 346



 Score = 40.7 bits (91), Expect = 0.045
 Identities = 31/101 (30%), Positives = 45/101 (44%), Gaps = 4/101 (3%)
 Frame = -3

Query: 817 LPGFIDVHVHVREPGANIKGRF*DLLPQXHWLVV--LTMICAMPNTNPSIVDRTAFDYAS 644
           LPG ID  VH REPG   K    DL           +T    MPNT P    + A D   
Sbjct: 57  LPGVIDPQVHFREPGLEHKE---DLFTASCACAKGGVTSFLEMPNTRPLTTTQQALD--D 111

Query: 643 TLARVSARC--DYALYVGASSTNYDTICELAPQAAALKMYL 527
            L R +++C  +Y  ++GA+  N   +    P    +K+++
Sbjct: 112 KLQRAASKCLVNYGFFIGATGDNTPELLAAHP-TPGIKIFM 151


>UniRef50_Q0W790 Cluster: Dihydroorotase; n=1; uncultured
           methanogenic archaeon RC-I|Rep: Dihydroorotase -
           Uncultured methanogenic archaeon RC-I
          Length = 451

 Score = 64.9 bits (151), Expect = 2e-09
 Identities = 34/76 (44%), Positives = 48/76 (63%), Gaps = 4/76 (5%)
 Frame = -1

Query: 234 AKVCPVLCSPEDQAELWR--NISIIDVFATDHAPHTVEEKNS--ENPPPGYPGLETILPL 67
           AK+ P +    D+  LW+  N   I+V A+DHAPHT++EKN      P G PG+ET+LPL
Sbjct: 269 AKMNPPIRHDSDRNALWKAVNDGSIEVLASDHAPHTLDEKNLPVREAPSGVPGVETMLPL 328

Query: 66  LLNAVHQGRLTIEDLL 19
           +L AV   RL ++ L+
Sbjct: 329 MLKAVADKRLPLQRLI 344



 Score = 35.5 bits (78), Expect = 1.7
 Identities = 25/79 (31%), Positives = 38/79 (48%)
 Frame = -3

Query: 832 GNIVKLPGFIDVHVHVREPGANIKGRF*DLLPQXHWLVVLTMICAMPNTNPSIVDRTAFD 653
           G +V +PG ID HVH R+     K  +        +  V T++  MPN++P   D  AF 
Sbjct: 46  GRLV-MPGVIDSHVHFRDMRQEEKEDWLSGSKAALYGGVTTVV-DMPNSDPPTFDAEAFK 103

Query: 652 YASTLARVSARCDYALYVG 596
              T+A   +  D++L  G
Sbjct: 104 VKQTVAANRSMVDFSLNAG 122


>UniRef50_UPI0000DAE5C6 Cluster: hypothetical protein
           Rgryl_01000723; n=1; Rickettsiella grylli|Rep:
           hypothetical protein Rgryl_01000723 - Rickettsiella
           grylli
          Length = 409

 Score = 64.5 bits (150), Expect = 3e-09
 Identities = 37/78 (47%), Positives = 46/78 (58%), Gaps = 4/78 (5%)
 Frame = -1

Query: 240 GRAKVCPVLCSPEDQAELWRNIS--IIDVFATDHAPHTVEEKNSENP--PPGYPGLETIL 73
           G+A + P L S E Q  L+  I   IID   +DHAPHT EEK       P G PG+ET L
Sbjct: 262 GKAIMNPPLRSSEHQRALFSAIKLGIIDTIGSDHAPHTQEEKAKPYGLCPSGVPGIETAL 321

Query: 72  PLLLNAVHQGRLTIEDLL 19
           PLLL A HQ  +T+ D++
Sbjct: 322 PLLLEAYHQDLITLTDIV 339



 Score = 50.4 bits (115), Expect = 6e-05
 Identities = 28/71 (39%), Positives = 42/71 (59%), Gaps = 7/71 (9%)
 Frame = -2

Query: 437 HAE-REKTAAVIL------MASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHH 279
           H+E R+++AA+I       +  L    ++I HV+ ++EI +I  AKE G+ +  E  PHH
Sbjct: 190 HSEIRDESAAIIAVKKAIQLVRLYKTRLYILHVSTRQEIDLIAQAKEEGLPIFAETTPHH 249

Query: 278 LFLNSNDITKL 246
           LFLN ND   L
Sbjct: 250 LFLNVNDYPDL 260



 Score = 33.1 bits (72), Expect = 8.9
 Identities = 25/106 (23%), Positives = 43/106 (40%), Gaps = 5/106 (4%)
 Frame = -3

Query: 829 NIVKLPGFIDVHVHVREPGANIKGRF*DLLPQXHWLVVLTMICAMPNTNPSIVDRTAFDY 650
           +++  PG ID HVH R PG   K  +     +       T +  MPNT P  + + A   
Sbjct: 31  HLLVFPGLIDPHVHFRTPGLEYKENW-TTAAKASIKGGYTTVFDMPNTLPPTITKEALIE 89

Query: 649 AST-----LARVSARCDYALYVGASSTNYDTICELAPQAAALKMYL 527
                   L  +     Y L+ GA   +   I ++  +   +K+++
Sbjct: 90  KKALIDKQLKAIGIPLRYHLFFGADKHHLHEIKKVNDKVIGIKVFM 135


>UniRef50_Q4JN07 Cluster: Dihydroorotase; n=3; Bacteria|Rep:
           Dihydroorotase - uncultured bacterium BAC13K9BAC
          Length = 444

 Score = 64.1 bits (149), Expect = 4e-09
 Identities = 29/72 (40%), Positives = 48/72 (66%), Gaps = 4/72 (5%)
 Frame = -1

Query: 222 PVLCSPEDQAELWR--NISIIDVFATDHAPHTVEEKNSENP--PPGYPGLETILPLLLNA 55
           P +   + Q  LW   N  ++D+ A+DHAPHT++EK+   P  P G PG++T++P++LN 
Sbjct: 281 PPIREKKHQDALWDALNSGVVDIVASDHAPHTLDEKSQIYPKSPSGTPGVQTLVPIMLNH 340

Query: 54  VHQGRLTIEDLL 19
           V+ G+LT+  L+
Sbjct: 341 VNNGKLTLAKLV 352



 Score = 44.0 bits (99), Expect = 0.005
 Identities = 31/92 (33%), Positives = 41/92 (44%), Gaps = 3/92 (3%)
 Frame = -3

Query: 829 NIVKLPGFIDVHVHVREPGANIKGRF*DLLPQXHWLVV---LTMICAMPNTNPSIVDRTA 659
           N+  LPG ID  VH REPG  ++G+  + L       V   +T I  MPNTNP  +    
Sbjct: 51  NLTVLPGVIDSQVHFREPG--LEGK--ENLESGMLAAVSGGVTSIFEMPNTNPLTITPET 106

Query: 658 FDYASTLARVSARCDYALYVGASSTNYDTICE 563
                  A   A  DYA Y+G +      + E
Sbjct: 107 IQDKLNRASKGAWTDYAFYLGGTMRTSSNLSE 138


>UniRef50_Q58885 Cluster: Dihydroorotase; n=6; Methanococcales|Rep:
           Dihydroorotase - Methanococcus jannaschii
          Length = 423

 Score = 63.3 bits (147), Expect = 7e-09
 Identities = 33/79 (41%), Positives = 49/79 (62%), Gaps = 4/79 (5%)
 Frame = -1

Query: 243 KGRAKVCPVLCSPEDQAELWRNI--SIIDVFATDHAPHTVEEK--NSENPPPGYPGLETI 76
           KG  K  P L   +D   L + I    +D+ A+DHAPH +E+K  N +N P G PG+ETI
Sbjct: 269 KGFGKFNPPLREKDDNIALIKGIVNKDVDIIASDHAPHLLEDKLKNVKNCPSGIPGIETI 328

Query: 75  LPLLLNAVHQGRLTIEDLL 19
           +PL LN V++G +++ D +
Sbjct: 329 VPLTLNLVNKGLISLFDAI 347



 Score = 53.6 bits (123), Expect = 6e-06
 Identities = 34/107 (31%), Positives = 53/107 (49%), Gaps = 2/107 (1%)
 Frame = -2

Query: 539 KDVLK*NFYNFLLEDMTIWQKHFQSWPKKMPVCTHAEREKTAAVILMASLLDRPVHICHV 360
           KDV+  N   + L     W  H +   +K  V    E  K   +I   S     VH CH+
Sbjct: 172 KDVINENLKKYQLNS---WIDHCKIRDEKSEVEAVKEVIKNLKIIDRQSNKKPHVHFCHI 228

Query: 359 ARKEEILIIKAAKE--RGVKVTCEVCPHHLFLNSNDITKLEKGEQKY 225
           + KE + +IK  ++  + +K+T EV PHH++LN  D+ +  KG  K+
Sbjct: 229 STKEALYLIKKVRQELKNIKITVEVTPHHIYLN-KDMAEELKGFGKF 274


>UniRef50_Q7NF57 Cluster: Dihydroorotase; n=12; Cyanobacteria|Rep:
           Dihydroorotase - Gloeobacter violaceus
          Length = 443

 Score = 62.9 bits (146), Expect = 1e-08
 Identities = 32/77 (41%), Positives = 46/77 (59%), Gaps = 4/77 (5%)
 Frame = -1

Query: 237 RAKVCPVLCSPEDQAELWRNI--SIIDVFATDHAPHTVEEKNSE--NPPPGYPGLETILP 70
           RAK  P L S  D+  +W  +   +ID  ATDHAPH + EK+ +    P G PG+ET LP
Sbjct: 274 RAKQNPPLRSEADREAMWAGLRSGLIDFVATDHAPHLLSEKDRDYAEAPAGMPGVETSLP 333

Query: 69  LLLNAVHQGRLTIEDLL 19
           L+L A+ +G +  E ++
Sbjct: 334 LMLTALARGEVNFEQIV 350



 Score = 50.4 bits (115), Expect = 6e-05
 Identities = 34/107 (31%), Positives = 52/107 (48%), Gaps = 5/107 (4%)
 Frame = -3

Query: 832 GNIVKLPGFIDVHVHVREPGANIKGRF*DLLPQXHWLVV---LTMICAMPNTNPSIVDRT 662
           G  V LPG ID  VH REPG   K    + L    W      +T    MPNT+P     T
Sbjct: 51  GGRVLLPGVIDPQVHFREPGKEYK----EDLQTGSWACARGGVTSFLEMPNTSPPTT--T 104

Query: 661 AFDYASTLARVSARC--DYALYVGASSTNYDTICELAPQAAALKMYL 527
                  LAR +++C  +Y  +VGA++ N + + + A  +  +K+++
Sbjct: 105 VERLEDKLARAASKCVVNYGFFVGATADNIEQLQQAAGLSCGVKIFM 151



 Score = 36.7 bits (81), Expect = 0.72
 Identities = 19/55 (34%), Positives = 33/55 (60%)
 Frame = -2

Query: 428 REKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNS 264
           R  TA  + ++    R +HI H++  EE+ +++A  ++   VT EV P HLFL++
Sbjct: 213 RLATAQALELSRRYRRRLHILHLSAAEELELLRA--DKPAWVTAEVIPQHLFLST 265


>UniRef50_Q8ZZC7 Cluster: Dihydroorotase; n=4; Pyrobaculum|Rep:
           Dihydroorotase - Pyrobaculum aerophilum
          Length = 383

 Score = 62.5 bits (145), Expect = 1e-08
 Identities = 33/81 (40%), Positives = 47/81 (58%), Gaps = 2/81 (2%)
 Frame = -1

Query: 240 GRAKVCPVLCSPEDQAELWRNIS--IIDVFATDHAPHTVEEKNSENPPPGYPGLETILPL 67
           G   V P L +PE +  L    +  ++D++ATDHAPHT+EEK S  PPPG   L+  L L
Sbjct: 232 GLCHVNPRLRTPEMRKRLLAAFASGLVDIYATDHAPHTLEEKRSGAPPPGICSLDVALSL 291

Query: 66  LLNAVHQGRLTIEDLLCRIRH 4
           LL    +G +T+ D++    H
Sbjct: 292 LLTLWKRGVVTLSDVVRLYSH 312


>UniRef50_O28034 Cluster: Dihydroorotase; n=1; Archaeoglobus
           fulgidus|Rep: Dihydroorotase - Archaeoglobus fulgidus
          Length = 403

 Score = 61.3 bits (142), Expect = 3e-08
 Identities = 32/73 (43%), Positives = 46/73 (63%)
 Frame = -1

Query: 228 VCPVLCSPEDQAELWRNISIIDVFATDHAPHTVEEKNSENPPPGYPGLETILPLLLNAVH 49
           V P L   ED   L+RN   IDV A+DHAPHT+E+K  E    G+PG+ET+ PL +N   
Sbjct: 251 VNPPLREREDVEWLFRNFHRIDVLASDHAPHTLEDK--EAGASGFPGVETMYPLFVNLAS 308

Query: 48  QGRLTIEDLLCRI 10
           +G ++ + L+ +I
Sbjct: 309 KGYISFKTLVEKI 321



 Score = 35.9 bits (79), Expect = 1.3
 Identities = 27/86 (31%), Positives = 38/86 (44%), Gaps = 1/86 (1%)
 Frame = -3

Query: 823 VKLPGFIDVHVHVREPGANIKGRF*D-LLPQXHWLVVLTMICAMPNTNPSIVDRTAFDYA 647
           V LP  IDVHVH+R+     K       L   H  + L  +   PNT P + D   +   
Sbjct: 39  VILPAGIDVHVHLRDFAEKRKETIETGTLSALHGGICL--VVDQPNTKPPVDDAETYFRR 96

Query: 646 STLARVSARCDYALYVGASSTNYDTI 569
              A  S   DYAL +  +++N+  I
Sbjct: 97  MGKAEKSVYVDYALNLALTNSNHGKI 122


>UniRef50_A0B872 Cluster: Dihydroorotase, multifunctional complex
           type; n=1; Methanosaeta thermophila PT|Rep:
           Dihydroorotase, multifunctional complex type -
           Methanosaeta thermophila (strain DSM 6194 / PT)
           (Methanothrixthermophila (strain DSM 6194 / PT))
          Length = 432

 Score = 60.9 bits (141), Expect = 4e-08
 Identities = 33/72 (45%), Positives = 43/72 (59%), Gaps = 4/72 (5%)
 Frame = -1

Query: 231 KVCPVLCSPEDQAELWRNISI--IDVFATDHAPHTVEEKNSE--NPPPGYPGLETILPLL 64
           K  P L +  D   LW  +    IDV A+DHAPH  EEK  +  + PPG PG+ET+LPL+
Sbjct: 260 KTNPPLRNTADCDALWDGLRRRDIDVIASDHAPHLPEEKRDDIWHAPPGVPGVETMLPLM 319

Query: 63  LNAVHQGRLTIE 28
           L AV    +T+E
Sbjct: 320 LYAVKSNMITLE 331



 Score = 48.4 bits (110), Expect = 2e-04
 Identities = 19/44 (43%), Positives = 30/44 (68%)
 Frame = -2

Query: 377 VHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDITKL 246
           +HICH++  + + ++K  + R  KV+CEV PHHLFL+  D  +L
Sbjct: 214 IHICHISTADGLELVKRRRNR--KVSCEVAPHHLFLSRRDYRRL 255



 Score = 37.5 bits (83), Expect = 0.41
 Identities = 22/77 (28%), Positives = 39/77 (50%)
 Frame = -3

Query: 826 IVKLPGFIDVHVHVREPGANIKGRF*DLLPQXHWLVVLTMICAMPNTNPSIVDRTAFDYA 647
           ++ +PG ID+HVH R+PG   K  + +          +T +   PNT+P ++D  ++   
Sbjct: 47  MIIIPGVIDMHVHFRDPGYTHKEDW-ESGSISAAAGGVTTVVDQPNTDPPVMDAESYKEK 105

Query: 646 STLARVSARCDYALYVG 596
             LA+  +  D+ L  G
Sbjct: 106 LNLAKRRSIVDFCLNGG 122


>UniRef50_Q9HMH9 Cluster: Dihydroorotase; n=6; Halobacteriaceae|Rep:
           Dihydroorotase - Halobacterium salinarium (Halobacterium
           halobium)
          Length = 422

 Score = 60.1 bits (139), Expect = 7e-08
 Identities = 29/49 (59%), Positives = 35/49 (71%), Gaps = 2/49 (4%)
 Frame = -1

Query: 168 IDVFATDHAPHTVEEKNSE--NPPPGYPGLETILPLLLNAVHQGRLTIE 28
           IDV ATDHAPHT  EK ++  + P G PG+ET LPLLL A H+G L+ E
Sbjct: 285 IDVVATDHAPHTRAEKAADIWDAPSGVPGVETALPLLLGAAHRGELSYE 333



 Score = 34.3 bits (75), Expect = 3.9
 Identities = 18/44 (40%), Positives = 24/44 (54%)
 Frame = -2

Query: 377 VHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDITKL 246
           +HI H +  E +    AA   G   TCE  PHHLFL+ +D+  L
Sbjct: 219 IHIAHTSTPEGV---DAAAAGGA--TCEATPHHLFLSRDDLDDL 257



 Score = 33.9 bits (74), Expect = 5.1
 Identities = 24/76 (31%), Positives = 33/76 (43%)
 Frame = -3

Query: 817 LPGFIDVHVHVREPGANIKGRF*DLLPQXHWLVVLTMICAMPNTNPSIVDRTAFDYASTL 638
           LPG ID HVH R+PG   K  +           V T++   PNT P  V   A D  +  
Sbjct: 46  LPGMIDAHVHFRQPGFEHKETWASGSRSAAAGGVTTVV-DQPNTAPPTVTGDAVDEKAAH 104

Query: 637 ARVSARCDYALYVGAS 590
           A   +  D+ +  G +
Sbjct: 105 AAADSVVDWGVNGGVT 120


>UniRef50_Q2FLR3 Cluster: Dihydroorotase; n=3;
           Methanomicrobiales|Rep: Dihydroorotase -
           Methanospirillum hungatei (strain JF-1 / DSM 864)
          Length = 431

 Score = 59.3 bits (137), Expect = 1e-07
 Identities = 30/77 (38%), Positives = 48/77 (62%), Gaps = 2/77 (2%)
 Frame = -1

Query: 237 RAKVCPVLCSPEDQAELWRNISIIDVFATDHAPHTVEEKNSE--NPPPGYPGLETILPLL 64
           + KV P L S + + EL+     ID+  +DHAPHT  EK  E  + P G PG+ET++PLL
Sbjct: 260 QGKVNPPLRSEKVRRELFSCWDQIDIIGSDHAPHTRAEKGKEFEHAPSGIPGVETMIPLL 319

Query: 63  LNAVHQGRLTIEDLLCR 13
           +  V + +++I D++ +
Sbjct: 320 MGRVLEKKVSIADVIAK 336


>UniRef50_P77884 Cluster: Dihydroorotase; n=25; Bacilli|Rep:
           Dihydroorotase - Lactobacillus plantarum
          Length = 430

 Score = 58.0 bits (134), Expect = 3e-07
 Identities = 25/61 (40%), Positives = 36/61 (59%)
 Frame = -2

Query: 434 AEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 255
           +E  + A  +++A       H+CHV+  E + +I+ AK  G+ VTCEV PHHL L   DI
Sbjct: 210 SEAAQVARDVMLAEASGVHYHVCHVSTAESLRVIRNAKAAGINVTCEVSPHHLLLCDEDI 269

Query: 254 T 252
           T
Sbjct: 270 T 270



 Score = 39.9 bits (89), Expect = 0.078
 Identities = 27/69 (39%), Positives = 37/69 (53%), Gaps = 4/69 (5%)
 Frame = -1

Query: 231 KVCPVLCSPEDQAELWRNI--SIIDVFATDHAPHTVEEK--NSENPPPGYPGLETILPLL 64
           K+ P L S +D+A L   +    ID+ ATDHAPHT  EK  + +    G  G+ET    L
Sbjct: 277 KMNPPLRSAKDRAALVAGLLDGTIDMIATDHAPHTDAEKQGSMKTAAFGITGIETAFATL 336

Query: 63  LNAVHQGRL 37
             A+ + RL
Sbjct: 337 YTALVKTRL 345



 Score = 36.7 bits (81), Expect = 0.72
 Identities = 20/46 (43%), Positives = 25/46 (54%), Gaps = 1/46 (2%)
 Frame = -3

Query: 814 PGFIDVHVHVREPGANIKGRF-*DLLPQXHWLVVLTMICAMPNTNP 680
           PGF+DVHVH+R+PG   K       L   H     T + AMPN +P
Sbjct: 55  PGFVDVHVHLRDPGQTAKETIATGTLAAAHG--GFTTVGAMPNVDP 98


>UniRef50_Q30X37 Cluster: Dihydroorotase, multifunctional complex
           type; n=4; Desulfovibrionaceae|Rep: Dihydroorotase,
           multifunctional complex type - Desulfovibrio
           desulfuricans (strain G20)
          Length = 426

 Score = 57.6 bits (133), Expect = 4e-07
 Identities = 25/56 (44%), Positives = 38/56 (67%)
 Frame = -2

Query: 434 AEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLN 267
           AE  + A  IL+A  L  PVH+ H++ ++ + +I  AK+RGV+VT E CPH+L L+
Sbjct: 214 AESVQVARDILLAEYLGIPVHLAHISCRQSVELIAWAKQRGVRVTAETCPHYLLLD 269



 Score = 54.4 bits (125), Expect = 3e-06
 Identities = 30/76 (39%), Positives = 44/76 (57%), Gaps = 4/76 (5%)
 Frame = -1

Query: 234 AKVCPVLCSPEDQAELWRNIS--IIDVFATDHAPHTVEEKNS--ENPPPGYPGLETILPL 67
           AKV P L +P+D A + R ++   ID+  TDHAPH   EK++  +  P G  GL+T + L
Sbjct: 280 AKVNPPLRTPDDVAAMRRAVADGTIDILVTDHAPHAAHEKDTPLDEAPNGISGLDTAVAL 339

Query: 66  LLNAVHQGRLTIEDLL 19
               V +G LT  D++
Sbjct: 340 TWRLVQEGLLTEADMV 355


>UniRef50_A3ZRV3 Cluster: Dihydroorotase; n=1; Blastopirellula
           marina DSM 3645|Rep: Dihydroorotase - Blastopirellula
           marina DSM 3645
          Length = 444

 Score = 57.2 bits (132), Expect = 5e-07
 Identities = 32/76 (42%), Positives = 46/76 (60%), Gaps = 4/76 (5%)
 Frame = -1

Query: 234 AKVCPVLCSPEDQAELWRNI--SIIDVFATDHAPHTVEEKNSENP--PPGYPGLETILPL 67
           A++ P L S  D A L + +    I + ATDHAPH  E+K    P  P G PG+ET LPL
Sbjct: 268 AQMNPALKSAADNAALLQALLDDQIQIVATDHAPHRYEDKCQRYPDSPSGVPGVETSLPL 327

Query: 66  LLNAVHQGRLTIEDLL 19
           +L+ V + + T+ED++
Sbjct: 328 MLDLVAKEKCTLEDVV 343



 Score = 53.6 bits (123), Expect = 6e-06
 Identities = 34/102 (33%), Positives = 52/102 (50%), Gaps = 2/102 (1%)
 Frame = -3

Query: 817 LPGFIDVHVHVREPGANIKGRF*DLLPQXHWLVV--LTMICAMPNTNPSIVDRTAFDYAS 644
           LPG ID HVH+R+PG   K    DL           +T I  MPNT+P+ V +   +   
Sbjct: 51  LPGVIDAHVHMRDPGGTDKE---DLRTGSMAAAKGGVTTILDMPNTSPATVSQKLLEEKL 107

Query: 643 TLARVSARCDYALYVGASSTNYDTICELAPQAAALKMYLNET 518
           TLA V +  +Y  ++GA+  N   + + A +   +K+Y+  T
Sbjct: 108 TLASVKSIVNYGFFMGATIDNIGEL-KKAKRTPGIKIYMGST 148



 Score = 37.9 bits (84), Expect = 0.31
 Identities = 26/92 (28%), Positives = 42/92 (45%), Gaps = 7/92 (7%)
 Frame = -2

Query: 500 EDMTIWQKHFQSWPKKMPVCTHA-----EREKTAA--VILMASLLDRPVHICHVARKEEI 342
           ED  I  K+F+ +     V  H+     E E +A    + +A      +H+CH++     
Sbjct: 176 EDENIITKNFEEFGLTRNVVDHSRIRTPEAEASAVRKAVALAKEYKHRLHLCHMS---SA 232

Query: 341 LIIKAAKERGVKVTCEVCPHHLFLNSNDITKL 246
           L +   ++    +T EV PHHL LN +D   L
Sbjct: 233 LALAEFEDHADLITAEVTPHHLLLNESDYMNL 264


>UniRef50_Q28JR7 Cluster: Allantoinase; n=1; Jannaschia sp.
           CCS1|Rep: Allantoinase - Jannaschia sp. (strain CCS1)
          Length = 462

 Score = 56.8 bits (131), Expect = 6e-07
 Identities = 33/83 (39%), Positives = 48/83 (57%), Gaps = 10/83 (12%)
 Frame = -1

Query: 234 AKVCPVLCSPEDQAELWRNIS--IIDVFATDHAPHTVEEKNSEN-----PPPGYPGLETI 76
           AKV P +    DQ  LW+ I   +I+   TDHAP    EK +        PPG PG+E I
Sbjct: 288 AKVNPPIRFQSDQDALWQAIEDGVINYVTTDHAPFAKAEKQASEGDFPGAPPGVPGIEFI 347

Query: 75  LPLLLNAVHQGRLTIE---DLLC 16
           +P +L+AV +GRL+++   +L+C
Sbjct: 348 VPAMLDAVSRGRLSLKRAHELIC 370


>UniRef50_Q2NHZ6 Cluster: Dihydroorotase; n=1; Methanosphaera
           stadtmanae DSM 3091|Rep: Dihydroorotase - Methanosphaera
           stadtmanae (strain DSM 3091)
          Length = 429

 Score = 56.8 bits (131), Expect = 6e-07
 Identities = 28/56 (50%), Positives = 35/56 (62%), Gaps = 2/56 (3%)
 Frame = -1

Query: 180 NISIIDVFATDHAPHTVEEKNSEN--PPPGYPGLETILPLLLNAVHQGRLTIEDLL 19
           N++  D   TDHAPHT+EEK  +      G PGLET L LLL  V+  RLT+E L+
Sbjct: 288 NLNEFDSIGTDHAPHTIEEKEKDTWKSAAGIPGLETALKLLLTEVNNKRLTLEQLV 343



 Score = 47.2 bits (107), Expect = 5e-04
 Identities = 31/102 (30%), Positives = 51/102 (50%)
 Frame = -3

Query: 829 NIVKLPGFIDVHVHVREPGANIKGRF*DLLPQXHWLVVLTMICAMPNTNPSIVDRTAFDY 650
           NI+ +PG ID HVH+R+PG   K  +     Q       T I  MPNT P+   + AF  
Sbjct: 49  NII-IPGLIDTHVHLRDPGMTQKETW-TTGTQAAAHGGYTTIIDMPNTLPATDTKKAFQE 106

Query: 649 ASTLARVSARCDYALYVGASSTNYDTICELAPQAAALKMYLN 524
              +A   +  D+ L+ G   T  D +  ++ + A+ K++++
Sbjct: 107 KRNIATKKSYVDFGLHAGV-KTRQDVMDIMSEKPASYKIFMD 147



 Score = 39.1 bits (87), Expect = 0.14
 Identities = 13/38 (34%), Positives = 28/38 (73%)
 Frame = -2

Query: 377 VHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNS 264
           +H+CH++ ++ + +I  AKE+ + ++ E  PHH+FL++
Sbjct: 225 LHLCHISTRQTLELIHEAKEK-LNISIEATPHHIFLDN 261


>UniRef50_Q5HGN1 Cluster: Dihydroorotase; n=14; Bacillales|Rep:
           Dihydroorotase - Staphylococcus aureus (strain COL)
          Length = 424

 Score = 56.8 bits (131), Expect = 6e-07
 Identities = 25/59 (42%), Positives = 35/59 (59%)
 Frame = -2

Query: 431 EREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 255
           E  + A  +L+A       H+CHV+ KE + +I+ AK  G+ VT EV PHHL L  +DI
Sbjct: 208 ESVQIARDVLLAEAAGCHYHVCHVSTKESVRVIRDAKRAGIHVTAEVTPHHLLLTEDDI 266



 Score = 44.8 bits (101), Expect = 0.003
 Identities = 31/76 (40%), Positives = 39/76 (51%), Gaps = 5/76 (6%)
 Frame = -1

Query: 231 KVCPVLCSPEDQAELWRNI--SIIDVFATDHAPHTVEEKNS--ENPPPGYPGLETILPLL 64
           K+ P L S ED+  L   +    ID  ATDHAPH  +EK    E  P G  G ET  PLL
Sbjct: 274 KMNPPLRSTEDREALLEGLLDGTIDCIATDHAPHARDEKAQPMEKAPFGIVGSETAFPLL 333

Query: 63  -LNAVHQGRLTIEDLL 19
             + V  G  T++ L+
Sbjct: 334 YTHFVKNGDWTLQQLV 349



 Score = 41.9 bits (94), Expect = 0.019
 Identities = 20/45 (44%), Positives = 25/45 (55%)
 Frame = -3

Query: 814 PGFIDVHVHVREPGANIKGRF*DLLPQXHWLVVLTMICAMPNTNP 680
           PGF+DVHVH+REPG   K    +   +       T +C MPNT P
Sbjct: 52  PGFVDVHVHLREPGGEYKETI-ETGTKAAARGGFTTVCPMPNTRP 95


>UniRef50_A5ULX4 Cluster: Dihydroorotase, PyrC; n=1;
           Methanobrevibacter smithii ATCC 35061|Rep:
           Dihydroorotase, PyrC - Methanobrevibacter smithii
           (strain PS / ATCC 35061 / DSM 861)
          Length = 414

 Score = 56.4 bits (130), Expect = 8e-07
 Identities = 30/65 (46%), Positives = 42/65 (64%), Gaps = 5/65 (7%)
 Frame = -1

Query: 207 PEDQAELWRNISIID---VFATDHAPHTVEEKNSE--NPPPGYPGLETILPLLLNAVHQG 43
           P  +A+   NIS ID   +  TDHAPHT+E+KN    +  PG P LET++PLLL  V++G
Sbjct: 272 PLREAKYKINISDIDENTIIGTDHAPHTLEDKNQGVWSSSPGIPALETVVPLLLTQVNRG 331

Query: 42  RLTIE 28
            L ++
Sbjct: 332 NLDLK 336



 Score = 39.9 bits (89), Expect = 0.078
 Identities = 34/110 (30%), Positives = 48/110 (43%), Gaps = 1/110 (0%)
 Frame = -3

Query: 838 VHGNIVKLPGFIDVHVHVREPGANIKGRF*DLLPQXHWLVVLTMICAMPNTNPSIVDRTA 659
           + GN++ LPGFID HVH R+PG   K  F     +       T +  MPNT P      A
Sbjct: 42  IKGNLL-LPGFIDPHVHFRDPGLTQKEDF-KTGSESAANGGFTTVIDMPNTIPKTNTYDA 99

Query: 658 FDYASTLARVSARCDYALYVGASS-TNYDTICELAPQAAALKMYLNETFT 512
                 +A   +  +Y L  G ++    + I  L P A  + M L +  T
Sbjct: 100 LKEKIAIADEKSIVNYELQAGWNTLEEMEKIISLNPIAFKVFMDLEDNET 149


>UniRef50_A5UX77 Cluster: Dihydroorotase, multifunctional complex
           type; n=3; Chloroflexaceae|Rep: Dihydroorotase,
           multifunctional complex type - Roseiflexus sp. RS-1
          Length = 497

 Score = 56.0 bits (129), Expect = 1e-06
 Identities = 26/55 (47%), Positives = 34/55 (61%)
 Frame = -2

Query: 434 AEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFL 270
           AE    A  I +A +    +HICHV+    + +I+AAK RGV+VT EV PHHL L
Sbjct: 217 AEEAMVARDIALAEMTGAHLHICHVSTAGSVALIRAAKARGVRVTAEVTPHHLTL 271



 Score = 40.7 bits (91), Expect = 0.045
 Identities = 26/77 (33%), Positives = 38/77 (49%), Gaps = 4/77 (5%)
 Frame = -1

Query: 231 KVCPVLCSPEDQAELWRNI--SIIDVFATDHAPHTVEEKNSEN--PPPGYPGLETILPLL 64
           +V P L + +D   L   +    ID  A+DH P +  +K  E      G   LET L L 
Sbjct: 324 RVRPPLRTEQDVEALIEGLRDGTIDAIASDHEPQSAVDKECEYRLAASGISSLETALGLA 383

Query: 63  LNAVHQGRLTIEDLLCR 13
           L  VH+G+L + DL+ +
Sbjct: 384 LTLVHRGKLDLVDLVAK 400



 Score = 39.5 bits (88), Expect = 0.10
 Identities = 19/47 (40%), Positives = 25/47 (53%)
 Frame = -3

Query: 814 PGFIDVHVHVREPGANIKGRF*DLLPQXHWLVVLTMICAMPNTNPSI 674
           PGF+D+H HVREPG   K    +   +       T +C MP+T P I
Sbjct: 62  PGFLDLHAHVREPGEEHKETI-ETATKAAAAGGFTTLCVMPDTRPPI 107


>UniRef50_Q984Y5 Cluster: Dihydroorotase; n=50; cellular
           organisms|Rep: Dihydroorotase - Rhizobium loti
           (Mesorhizobium loti)
          Length = 489

 Score = 55.6 bits (128), Expect = 1e-06
 Identities = 25/58 (43%), Positives = 40/58 (68%), Gaps = 4/58 (6%)
 Frame = -1

Query: 189 LWRNIS--IIDVFATDHAPHTVEEKNSENP--PPGYPGLETILPLLLNAVHQGRLTIE 28
           +W  I+  I+DV  +DHAPHT+ EK    P  P G  G++T++P++L+ V+ GRLT++
Sbjct: 335 VWHGIAQGIVDVLGSDHAPHTLAEKAKPYPASPSGMTGVQTLVPIMLDHVNAGRLTLQ 392



 Score = 50.0 bits (114), Expect = 7e-05
 Identities = 35/104 (33%), Positives = 50/104 (48%), Gaps = 4/104 (3%)
 Frame = -3

Query: 817 LPGFIDVHVHVREPGANIKGRF*DLLPQXHWLVVLTMICAMPNTNPSIVDRTAFDYASTL 638
           LPG +D  VH REPG   K    +   +   L  +T +  MPNTNP          A  +
Sbjct: 101 LPGVVDSQVHFREPGLEHKEDL-ETGSRAAVLGGVTAVFEMPNTNPLTTSEATL--ADKV 157

Query: 637 ARVSAR--CDYALYVGASSTNYDTICEL--APQAAALKMYLNET 518
            R S R  CD+A +VG +  N   + EL   P AA +K+++  +
Sbjct: 158 RRGSGRMHCDFAFWVGGTRDNARDVGELERLPGAAGIKVFMGSS 201



 Score = 41.1 bits (92), Expect = 0.034
 Identities = 19/58 (32%), Positives = 34/58 (58%)
 Frame = -2

Query: 419 TAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDITKL 246
           T  ++ +A  +   +H+ H++  EEIL ++  K+     TCE  PHHL L+++D  +L
Sbjct: 262 TERLVRIARDVRARIHVLHISTAEEILFLEQHKD---VATCEATPHHLTLSADDYLRL 316


>UniRef50_Q73ID8 Cluster: Dihydroorotase; n=15; Rickettsiales|Rep:
           Dihydroorotase - Wolbachia pipientis wMel
          Length = 459

 Score = 55.2 bits (127), Expect = 2e-06
 Identities = 31/82 (37%), Positives = 47/82 (57%), Gaps = 4/82 (4%)
 Frame = -1

Query: 234 AKVCPVLCSPEDQAELWRNIS--IIDVFATDHAPHTVEEKNS--ENPPPGYPGLETILPL 67
           AK+ P L + ED+  +   +   +ID  ATDHAPH    K+   EN   G  GLET+LPL
Sbjct: 309 AKMNPPLRTEEDRLAMVEGLKTGVIDCIATDHAPHDRSSKDLPLENAAFGIVGLETMLPL 368

Query: 66  LLNAVHQGRLTIEDLLCRIRHE 1
            L   H G++ + D+L ++ ++
Sbjct: 369 SLELYHSGQMGLLDVLAKLTYK 390



 Score = 50.0 bits (114), Expect = 7e-05
 Identities = 24/54 (44%), Positives = 34/54 (62%)
 Frame = -2

Query: 410 VILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDITK 249
           ++LM  + +   HI HV+ K+ +  IK AK+ G+ VTCEV PHH F  + DI K
Sbjct: 251 ILLMKDMENVHYHILHVSSKDSLDAIKRAKDLGLNVTCEVTPHH-FTLTEDIVK 303



 Score = 38.3 bits (85), Expect = 0.24
 Identities = 27/90 (30%), Positives = 41/90 (45%)
 Frame = -3

Query: 826 IVKLPGFIDVHVHVREPGANIKGRF*DLLPQXHWLVVLTMICAMPNTNPSIVDRTAFDYA 647
           +V +PG ID+HVH REPG   K              V T++C  PNT P+I       Y 
Sbjct: 85  LVLMPGLIDIHVHFREPGQEHKETIYTGSKSAAAGGVTTVVC-QPNTVPAIDSVILAKYL 143

Query: 646 STLARVSARCDYALYVGASSTNYDTICELA 557
              A  ++  +   Y    +T+ + + E+A
Sbjct: 144 KYRALETSHVNVEFY-AKITTSEEHLTEMA 172


>UniRef50_Q5FPJ5 Cluster: Dihydroorotase; n=4; Proteobacteria|Rep:
           Dihydroorotase - Gluconobacter oxydans (Gluconobacter
           suboxydans)
          Length = 439

 Score = 55.2 bits (127), Expect = 2e-06
 Identities = 33/98 (33%), Positives = 49/98 (50%), Gaps = 2/98 (2%)
 Frame = -3

Query: 817 LPGFIDVHVHVREPGANIKGRF*DLLPQXHWLVVLTMICAMPNTNPSIVDRTAFDYASTL 638
           LPG ID HVH+R+PG        +   +   L  +  +  MPNT+PS+ D T  D+    
Sbjct: 53  LPGLIDAHVHLRDPGKPEVETL-ETGTRAAALGGIATVFDMPNTSPSVTDVTMIDWKRDH 111

Query: 637 ARVSARCDYALYVGASSTNYDTIC--ELAPQAAALKMY 530
            R +A  D  +YVGA+  N   +   E  P   A+K++
Sbjct: 112 IRKTAHVDVGIYVGATRENTPDLATLEQQPGVCAVKVF 149



 Score = 48.8 bits (111), Expect = 2e-04
 Identities = 30/82 (36%), Positives = 46/82 (56%), Gaps = 4/82 (4%)
 Frame = -1

Query: 252 KIGKGRAKVCPVLCSPEDQAELWRNI--SIIDVFATDHAPHTVEEKNSENP--PPGYPGL 85
           K+G G A + P L         WR +    +DV ++DHAPH +E K    P  P G  G 
Sbjct: 269 KLG-GLAVMNPPLRDRSHWEASWRAVRDGRVDVVSSDHAPHPLEAKKLPWPKCPAGLTGT 327

Query: 84  ETILPLLLNAVHQGRLTIEDLL 19
           +TI+P++L+ V+ GRL++  L+
Sbjct: 328 QTIVPVMLDHVNAGRLSLARLV 349


>UniRef50_Q4QEW1 Cluster: Dihydroorotase, putative; n=9;
           Trypanosomatidae|Rep: Dihydroorotase, putative -
           Leishmania major
          Length = 405

 Score = 55.2 bits (127), Expect = 2e-06
 Identities = 28/74 (37%), Positives = 38/74 (51%), Gaps = 6/74 (8%)
 Frame = -1

Query: 255 YKIGKGRAKVCPVLCSPEDQAELWRNI--SIIDVFATDHAPHTVEEKN----SENPPPGY 94
           Y     R KV P +  P+    LW  +    +D   TDHAPHT+ EK+    +  PP G 
Sbjct: 243 YSCCGARVKVNPPVRPPQHHEALWAGLLDGTVDCVGTDHAPHTIAEKDHCDAAAQPPSGM 302

Query: 93  PGLETILPLLLNAV 52
           P +E ++PLLL  V
Sbjct: 303 PAIEVVVPLLLTVV 316



 Score = 45.6 bits (103), Expect = 0.002
 Identities = 20/61 (32%), Positives = 37/61 (60%), Gaps = 2/61 (3%)
 Frame = -2

Query: 434 AEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAK--ERGVKVTCEVCPHHLFLNSN 261
           +E     + I +A     P+H+ HV+  + + +I+ A+  +  +++TCEV PHHLFL ++
Sbjct: 182 SEAASVQSAIALARQCRTPLHLAHVSTAQSLDLIREARAADPTLQLTCEVTPHHLFLTTS 241

Query: 260 D 258
           D
Sbjct: 242 D 242



 Score = 43.6 bits (98), Expect = 0.006
 Identities = 28/82 (34%), Positives = 38/82 (46%), Gaps = 2/82 (2%)
 Frame = -3

Query: 826 IVKLPGFIDVHVHVREPGANIKGRF*DLLPQXHWLVVLTMICAMPNTNP--SIVDRTAFD 653
           +V+LP  ID HVH REPG   K          ++   +T+ C MPNT+P    V   A  
Sbjct: 11  VVQLPPLIDCHVHFREPGLEHKADIASESTAAYY-GGITVACDMPNTSPPTQSVAALADK 69

Query: 652 YASTLARVSARCDYALYVGASS 587
            A   A   A C    + GA++
Sbjct: 70  VARAKATAHAHCQLFFFFGATA 91


>UniRef50_Q74DP4 Cluster: Dihydroorotase, multifunctional complex
           type; n=8; Bacteria|Rep: Dihydroorotase, multifunctional
           complex type - Geobacter sulfurreducens
          Length = 425

 Score = 54.8 bits (126), Expect = 3e-06
 Identities = 25/60 (41%), Positives = 35/60 (58%)
 Frame = -2

Query: 434 AEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 255
           AE   TA  + +A   + P+HI HV+    + II+ AK RGVKVTCE  PH+  L  + +
Sbjct: 210 AEDAATARDVYLAEFTNSPLHIAHVSTMGSLRIIRNAKARGVKVTCETAPHYFSLTDDAV 269



 Score = 48.4 bits (110), Expect = 2e-04
 Identities = 33/76 (43%), Positives = 44/76 (57%), Gaps = 4/76 (5%)
 Frame = -1

Query: 234 AKVCPVLCSPEDQAELWRNIS--IIDVFATDHAPHTVEEKNSE-NPP-PGYPGLETILPL 67
           AK+ P L + +D A +   +    ID  ATDHAPH ++EK+ E N    G  GLET LPL
Sbjct: 276 AKMNPPLRTADDLAAVKEALKDGTIDAIATDHAPHHLDEKDVEFNVALNGIIGLETSLPL 335

Query: 66  LLNAVHQGRLTIEDLL 19
            L  V +G LT+  L+
Sbjct: 336 SLKLVEEGVLTLPALV 351



 Score = 35.9 bits (79), Expect = 1.3
 Identities = 20/67 (29%), Positives = 31/67 (46%), Gaps = 2/67 (2%)
 Frame = -3

Query: 826 IVKLPGFIDVHVHVREPGANIKGRF*DLLPQXHWLVV--LTMICAMPNTNPSIVDRTAFD 653
           ++  PG ID+HVH+R+PG   K    D++           T +  MPNT P   ++    
Sbjct: 51  LIVTPGLIDMHVHLRDPGLEYKE---DIVTGTRAAAAGGFTSVACMPNTKPVNDNKAVTS 107

Query: 652 YASTLAR 632
           Y    A+
Sbjct: 108 YIVAKAK 114


>UniRef50_P25995 Cluster: Dihydroorotase; n=41; Bacteria|Rep:
           Dihydroorotase - Bacillus subtilis
          Length = 428

 Score = 54.8 bits (126), Expect = 3e-06
 Identities = 20/44 (45%), Positives = 31/44 (70%)
 Frame = -2

Query: 374 HICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDITKLE 243
           H+CH++ KE + +++ AK+ G++VT EV PHHL L   DI  L+
Sbjct: 227 HVCHISTKESVRVVRDAKKAGIRVTAEVSPHHLLLCDEDIPGLD 270



 Score = 46.4 bits (105), Expect = 9e-04
 Identities = 24/42 (57%), Positives = 28/42 (66%), Gaps = 2/42 (4%)
 Frame = -1

Query: 231 KVCPVLCSPEDQAELWRNI--SIIDVFATDHAPHTVEEKNSE 112
           K+ P L SPED+A L   +    ID  ATDHAPHT EEKN+E
Sbjct: 274 KMNPPLRSPEDRAALIEGLLDGTIDFIATDHAPHTEEEKNTE 315



 Score = 37.5 bits (83), Expect = 0.41
 Identities = 19/45 (42%), Positives = 24/45 (53%)
 Frame = -3

Query: 814 PGFIDVHVHVREPGANIKGRF*DLLPQXHWLVVLTMICAMPNTNP 680
           PGF+D+HVH REPG   K    +   +       T + AMPNT P
Sbjct: 53  PGFVDLHVHFREPGGEKKETI-ETGAKAAGRGGYTTVAAMPNTRP 96


>UniRef50_Q9PEP0 Cluster: Dihydroorotase; n=54; cellular
           organisms|Rep: Dihydroorotase - Xylella fastidiosa
          Length = 449

 Score = 54.4 bits (125), Expect = 3e-06
 Identities = 37/100 (37%), Positives = 49/100 (49%), Gaps = 3/100 (3%)
 Frame = -3

Query: 817 LPGFIDVHVHVREPGANIKGRF*DLLPQXHWLVV--LTMICAMPNTNPSIVDRTAFDYAS 644
           LPG ID  VH REPG   KG   D+  +    V   LT    MPNTNP  +D  A     
Sbjct: 53  LPGMIDDQVHFREPGLTHKG---DIASESAAAVAGGLTSFMDMPNTNPPTLDVAALQAKY 109

Query: 643 TLARVSARCDYALYVGASSTNYDTICELAPQAA-ALKMYL 527
             A   A  +Y  Y+GAS+ N   I  L P+ +  +K+++
Sbjct: 110 DAASGRAWGNYGFYLGASNDNLAAIQALDPKTSPGIKVFM 149



 Score = 51.6 bits (118), Expect = 2e-05
 Identities = 25/58 (43%), Positives = 34/58 (58%), Gaps = 2/58 (3%)
 Frame = -1

Query: 171 IIDVFATDHAPHTVEEKNS--ENPPPGYPGLETILPLLLNAVHQGRLTIEDLLCRIRH 4
           +IDV ATDHAPHT EEK       P G P ++  L   L  VH GRL++ +++ +  H
Sbjct: 308 VIDVLATDHAPHTWEEKQQPYAQAPSGLPLVQYALVAALELVHAGRLSVTEIVRKFAH 365


>UniRef50_Q3AC01 Cluster: Dihydroorotase; n=1; Carboxydothermus
           hydrogenoformans Z-2901|Rep: Dihydroorotase -
           Carboxydothermus hydrogenoformans (strain Z-2901 / DSM
           6008)
          Length = 430

 Score = 54.4 bits (125), Expect = 3e-06
 Identities = 34/79 (43%), Positives = 46/79 (58%), Gaps = 5/79 (6%)
 Frame = -1

Query: 231 KVCPVLCSPEDQAELWRNI--SIIDVFATDHAPHTVEEKNSE--NPPPGYPGLETILPLL 64
           KV P L   E+Q  L + +   +IDV ATDHAPH   EKN E  + P G  GLET  P+L
Sbjct: 275 KVNPPLREAEEQKALLKGLLEGVIDVIATDHAPHASYEKNVEFNDAPFGIEGLETAFPVL 334

Query: 63  -LNAVHQGRLTIEDLLCRI 10
               V + ++T+E LL ++
Sbjct: 335 YTELVLKKKITLEKLLLKM 353



 Score = 45.6 bits (103), Expect = 0.002
 Identities = 19/46 (41%), Positives = 30/46 (65%)
 Frame = -2

Query: 407 ILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFL 270
           I +A +    +H+ H++  E + ++ AAK+ G+KVT EV PHHL L
Sbjct: 217 IEIAKMTGAKLHVAHLSTAEGVRLVAAAKKLGLKVTAEVTPHHLVL 262


>UniRef50_Q2RGZ6 Cluster: D-hydantoinase; n=1; Moorella
           thermoacetica ATCC 39073|Rep: D-hydantoinase - Moorella
           thermoacetica (strain ATCC 39073)
          Length = 454

 Score = 54.0 bits (124), Expect = 4e-06
 Identities = 31/77 (40%), Positives = 47/77 (61%), Gaps = 7/77 (9%)
 Frame = -1

Query: 228 VCPVLCSPEDQAELWRNISIID--VFATDHAPHTVEEKNSE----NPPPGYPGLETILPL 67
           +CP L + +D   LW++++  D  V ATDH  ++ E+K +     N P G PG ET+LPL
Sbjct: 283 MCPPLRTVKDNRILWQHLASGDLQVVATDHCSYSPEQKAAGTAFYNTPSGVPGTETLLPL 342

Query: 66  LLN-AVHQGRLTIEDLL 19
           L +  V QGRLT+  ++
Sbjct: 343 LYSYGVRQGRLTLPQMV 359



 Score = 40.3 bits (90), Expect = 0.059
 Identities = 22/55 (40%), Positives = 30/55 (54%)
 Frame = -2

Query: 434 AEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFL 270
           AE +    VI  A+    PV+I HV+      +I AA+ RG +V  E CPH+L L
Sbjct: 214 AEVKAIEKVIRQAAAAGAPVYIVHVSTGGGAELIAAARARGQQVFGETCPHYLLL 268


>UniRef50_P07259 Cluster: Protein URA1 [Includes: Glutamine-dependent
            carbamoyl-phosphate synthase (EC 6.3.5.5); Aspartate
            carbamoyltransferase (EC 2.1.3.2)]; n=133; cellular
            organisms|Rep: Protein URA1 [Includes:
            Glutamine-dependent carbamoyl-phosphate synthase (EC
            6.3.5.5); Aspartate carbamoyltransferase (EC 2.1.3.2)] -
            Saccharomyces cerevisiae (Baker's yeast)
          Length = 2214

 Score = 54.0 bits (124), Expect = 4e-06
 Identities = 24/69 (34%), Positives = 41/69 (59%)
 Frame = -2

Query: 464  WPKKMPVCTHAEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCP 285
            WP +  V   A+    A+V+L+ SL +R +HI  V+ KE++ +I   K +  +VTC+V  
Sbjct: 1623 WPTEKQVIAEAKTADLASVLLLTSLQNRSIHITGVSNKEDLALIMTVKAKDPRVTCDVNI 1682

Query: 284  HHLFLNSND 258
            + LF+  +D
Sbjct: 1683 YSLFIAQDD 1691



 Score = 48.0 bits (109), Expect = 3e-04
 Identities = 25/69 (36%), Positives = 37/69 (53%)
 Frame = -1

Query: 216  LCSPEDQAELWRNISIIDVFATDHAPHTVEEKNSENPPPGYPGLETILPLLLNAVHQGRL 37
            L + EDQ   W N+  ID F+    P  +          G  G++  LPLLL AV +G+L
Sbjct: 1698 LPTKEDQEFFWNNLDSIDAFSVGALPVALANVTGNKVDVGM-GIKDSLPLLLAAVEEGKL 1756

Query: 36   TIEDLLCRI 10
            TI+D++ R+
Sbjct: 1757 TIDDIVLRL 1765


>UniRef50_Q0LDY3 Cluster: Dihydroorotase; n=2; Chloroflexi
           (class)|Rep: Dihydroorotase - Herpetosiphon aurantiacus
           ATCC 23779
          Length = 473

 Score = 53.6 bits (123), Expect = 6e-06
 Identities = 32/80 (40%), Positives = 44/80 (55%), Gaps = 4/80 (5%)
 Frame = -1

Query: 237 RAKVCPVLCSPEDQAELWRNI--SIIDVFATDHAPHTVEEKNSEN--PPPGYPGLETILP 70
           R +V P L + ED A L   +    ID  ATDHAPHT  +K  E     PG+ GLE  LP
Sbjct: 298 RTRVSPPLRTSEDVAALIAGLRDGTIDAVATDHAPHTHVDKECEYGFASPGFTGLELALP 357

Query: 69  LLLNAVHQGRLTIEDLLCRI 10
           ++L  V   ++ I +L+ R+
Sbjct: 358 MVLTLVQTMQIDIVELISRM 377



 Score = 47.6 bits (108), Expect = 4e-04
 Identities = 24/52 (46%), Positives = 31/52 (59%)
 Frame = -2

Query: 431 EREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHL 276
           E    A  I +A      +HICHV+    + +I+AAK RGV+VT EV PHHL
Sbjct: 216 EEVMIARDIALAEETGGRLHICHVSTAGGVELIRAAKARGVRVTGEVTPHHL 267



 Score = 42.7 bits (96), Expect = 0.011
 Identities = 33/97 (34%), Positives = 46/97 (47%), Gaps = 7/97 (7%)
 Frame = -3

Query: 814 PGFIDVHVHVREPGANIKGRF*DLLPQXHWLVV---LTMICAMPNTNPSI----VDRTAF 656
           PGFID+H H+REPG   +G+  + +       V    T IC MPNTNPS+    + R  F
Sbjct: 60  PGFIDIHTHLREPG--FEGK--ETIATGMDAAVRGGYTTICPMPNTNPSLDSAPLIRQQF 115

Query: 655 DYASTLARVSARCDYALYVGASSTNYDTICELAPQAA 545
           D A+    +      A+ +G        + ELA   A
Sbjct: 116 DIAARHGPIHVLPIGAVTLGREGKVLAPLVELAEAGA 152


>UniRef50_A4GJR5 Cluster: Dihydroorotase; n=6; Bacteria|Rep:
           Dihydroorotase - uncultured marine bacterium HF10_45G01
          Length = 435

 Score = 53.6 bits (123), Expect = 6e-06
 Identities = 25/76 (32%), Positives = 43/76 (56%), Gaps = 4/76 (5%)
 Frame = -1

Query: 234 AKVCPVLCSPEDQAELWRNI--SIIDVFATDHAPHTVEEKNS--ENPPPGYPGLETILPL 67
           A++ P L        LW  +  +  D   +DHAPH  E K+    N P G PG++T++P+
Sbjct: 271 AQMNPPLRDKSHYDRLWYGVRNNFNDTIGSDHAPHLKENKDKVYPNTPSGMPGVQTLMPV 330

Query: 66  LLNAVHQGRLTIEDLL 19
           +LN ++ G+L++  L+
Sbjct: 331 MLNHINNGKLSLNQLI 346



 Score = 46.8 bits (106), Expect = 7e-04
 Identities = 30/88 (34%), Positives = 40/88 (45%), Gaps = 2/88 (2%)
 Frame = -3

Query: 817 LPGFIDVHVHVREPGANIKGRF*DLLPQXHWLVV--LTMICAMPNTNPSIVDRTAFDYAS 644
           LPG ID   H REPG+       DL       +   +T +  MPNTNP   +   F    
Sbjct: 51  LPGCIDTQTHFREPGSTDTE---DLHSGSRAAIAGGITSVFEMPNTNPPTSNMKEFQRKL 107

Query: 643 TLARVSARCDYALYVGASSTNYDTICEL 560
            LA+     +YA Y GA++ N D +  L
Sbjct: 108 DLAKNRMYSNYAFYFGATADNADDLASL 135


>UniRef50_A4ECL5 Cluster: Dihydroorotase; n=1; Collinsella
           aerofaciens ATCC 25986|Rep: Dihydroorotase - Collinsella
           aerofaciens ATCC 25986
          Length = 429

 Score = 53.6 bits (123), Expect = 6e-06
 Identities = 24/59 (40%), Positives = 35/59 (59%)
 Frame = -2

Query: 431 EREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 255
           E  + A  I +A L    +HI H++    + I++A K  GV+VTCE  PHH+FL  ND+
Sbjct: 210 EELQIARDIEIAKLTGAKLHIQHISTAHGLEIVRAGKAAGVQVTCEATPHHMFLTENDL 268



 Score = 44.0 bits (99), Expect = 0.005
 Identities = 22/67 (32%), Positives = 35/67 (52%)
 Frame = -3

Query: 817 LPGFIDVHVHVREPGANIKGRF*DLLPQXHWLVVLTMICAMPNTNPSIVDRTAFDYASTL 638
           +PG +D+HVH+REPG  +K    +   +       T +CAMPNT+P   + T  ++  + 
Sbjct: 53  VPGLVDMHVHLREPGYEVKEDI-ESGTRAAAKGGFTGVCAMPNTDPVTDNGTVVEFVKSR 111

Query: 637 ARVSARC 617
           A     C
Sbjct: 112 AAEVGHC 118



 Score = 40.7 bits (91), Expect = 0.045
 Identities = 28/72 (38%), Positives = 39/72 (54%), Gaps = 5/72 (6%)
 Frame = -1

Query: 231 KVCPVLCSPEDQAELWRNI--SIIDVFATDHAPHTVEEK--NSENPPPGYPGLETILPLL 64
           KV P L + ED   + + +    +D   TDHAPHT  EK    E  P G  GLET L L+
Sbjct: 277 KVNPPLRTEEDAEAIRQGVIDGTVDAIVTDHAPHTPWEKAREFELAPFGMIGLETSLSLV 336

Query: 63  L-NAVHQGRLTI 31
           L   V+ G++++
Sbjct: 337 LTELVNTGKMSM 348


>UniRef50_Q8XL61 Cluster: Dihydroorotase; n=12; Bacteria|Rep:
           Dihydroorotase - Clostridium perfringens
          Length = 399

 Score = 53.2 bits (122), Expect = 8e-06
 Identities = 26/57 (45%), Positives = 34/57 (59%)
 Frame = -2

Query: 434 AEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNS 264
           AE   T   I +A  +D  +H+ HV+ KE +  I   K  GVKVTCE+ PHHL LN+
Sbjct: 191 AENMMTWRDITLAKFVDCRLHMSHVSTKEAMKYIIEGKNDGVKVTCEITPHHLALNN 247



 Score = 34.3 bits (75), Expect = 3.9
 Identities = 19/59 (32%), Positives = 26/59 (44%)
 Frame = -3

Query: 826 IVKLPGFIDVHVHVREPGANIKGRF*DLLPQXHWLVVLTMICAMPNTNPSIVDRTAFDY 650
           +V +P FID H H R+PG   K    +   +       T +  MPNT P    +   DY
Sbjct: 47  LVLMPAFIDTHAHFRDPGFEYKEDI-ESGSKAAVRGGYTTVTLMPNTKPVCSSKEILDY 104


>UniRef50_Q89PZ7 Cluster: D-hydantoinase; n=5;
           Alphaproteobacteria|Rep: D-hydantoinase - Bradyrhizobium
           japonicum
          Length = 489

 Score = 53.2 bits (122), Expect = 8e-06
 Identities = 24/62 (38%), Positives = 40/62 (64%)
 Frame = -2

Query: 434 AEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 255
           +E E    +I MA+L+D+P+ I HV+  E   +I+ ++ +G+KV  E CP +LFL + D+
Sbjct: 220 SEAEAFTRLIGMAALIDQPIMIFHVSTAEGAKVIRDSRGQGLKVFAETCPQYLFLTAADL 279

Query: 254 TK 249
            K
Sbjct: 280 DK 281



 Score = 41.5 bits (93), Expect = 0.025
 Identities = 32/80 (40%), Positives = 44/80 (55%), Gaps = 17/80 (21%)
 Frame = -1

Query: 216 LCSPE-----DQAELWRNISIIDV--FATDHAPHTVEE--KNSENPPP-------GYPGL 85
           +CSP      DQ  LW+ +S+ D+   ++DHAP+  +E  K    P P       G PGL
Sbjct: 290 MCSPPPRTHADQEALWQALSLGDLQTISSDHAPYRFDETGKLRAGPNPNFKQVANGLPGL 349

Query: 84  ETILPLLLNA-VHQGRLTIE 28
           E  LPLL +A V +GRL +E
Sbjct: 350 ELRLPLLFDAMVSKGRLGLE 369


>UniRef50_Q6U5R7 Cluster: PyrC; n=6; Gammaproteobacteria|Rep: PyrC -
           Klebsiella pneumoniae
          Length = 448

 Score = 53.2 bits (122), Expect = 8e-06
 Identities = 31/82 (37%), Positives = 46/82 (56%), Gaps = 4/82 (4%)
 Frame = -1

Query: 237 RAKVCPVLCSPEDQAELWRNIS--IIDVFATDHAPHTVEEKNSE--NPPPGYPGLETILP 70
           + K  P + +   Q  LW+ ++  IIDV ATDHAPH +EEK S+    P G P ++  LP
Sbjct: 282 KLKCNPSVKTSFHQEALWKGVNEGIIDVIATDHAPHLLEEKQSDYFAAPSGLPLVQHALP 341

Query: 69  LLLNAVHQGRLTIEDLLCRIRH 4
            LL+   +G  T E ++ +  H
Sbjct: 342 ALLDMCSRGIFTPEMVVRKTSH 363



 Score = 47.2 bits (107), Expect = 5e-04
 Identities = 32/100 (32%), Positives = 48/100 (48%), Gaps = 3/100 (3%)
 Frame = -3

Query: 817 LPGFIDVHVHVREPGANIKGRF*DLLPQXHWLVV--LTMICAMPNTNPSIVDRTAFDYAS 644
           +PG ID  VH REPG   KG    +  +    V+  +T    MPN  P    R A     
Sbjct: 53  IPGMIDDQVHFREPGLTHKG---TIATESAAAVMGGITSFMEMPNVTPPTTTRQALREKF 109

Query: 643 TLARVSARCDYALYVGASSTNYDTICEL-APQAAALKMYL 527
             A  S+  +++ Y GA++ N D +  L A QA  +K+++
Sbjct: 110 QRASRSSLANHSFYFGATNDNLDELKALTASQACGVKVFM 149



 Score = 35.5 bits (78), Expect = 1.7
 Identities = 16/48 (33%), Positives = 25/48 (52%), Gaps = 4/48 (8%)
 Frame = -2

Query: 377 VHICHVARKEEILIIKAAKE----RGVKVTCEVCPHHLFLNSNDITKL 246
           +H+ H+   +E+++  AA      R   +T E C HHLF N +D   L
Sbjct: 232 LHVLHITTADELVLFDAAPTLEALRQKTITAEACVHHLFFNYDDYETL 279


>UniRef50_Q1VNG2 Cluster: Dihydroorotase; n=2; Psychroflexus torquis
           ATCC 700755|Rep: Dihydroorotase - Psychroflexus torquis
           ATCC 700755
          Length = 441

 Score = 53.2 bits (122), Expect = 8e-06
 Identities = 28/77 (36%), Positives = 44/77 (57%), Gaps = 4/77 (5%)
 Frame = -1

Query: 237 RAKVCPVLCSPEDQAELWRNIS--IIDVFATDHAPHTVEEKNSENP--PPGYPGLETILP 70
           R ++ P +   +D+  LW+ +    +   ATDHAPHT+E K    P  P G PG+ET L 
Sbjct: 264 RLQMNPPVRYKKDRETLWKQLKSGTVQCIATDHAPHTLEAKALGFPKAPSGMPGVETSLA 323

Query: 69  LLLNAVHQGRLTIEDLL 19
           ++L   + G  +IED++
Sbjct: 324 VMLTHANDGACSIEDVV 340



 Score = 33.9 bits (74), Expect = 5.1
 Identities = 26/81 (32%), Positives = 33/81 (40%), Gaps = 2/81 (2%)
 Frame = -3

Query: 817 LPGFIDVHVHVREPGANIKGRF*DLLPQXHWLVV--LTMICAMPNTNPSIVDRTAFDYAS 644
           LPG ID  VH R+PG   K    DL       V   +T    MPN  PSI      +   
Sbjct: 28  LPGMIDPQVHFRDPGQPEKE---DLGSGSAAAVSGGITSFLDMPNNKPSITTLEGMNMKL 84

Query: 643 TLARVSARCDYALYVGASSTN 581
             A      +Y  ++GA+  N
Sbjct: 85  KTASEKCVNNYGFFIGATPDN 105


>UniRef50_A5NZP0 Cluster: Dihydropyrimidinase; n=5;
           Proteobacteria|Rep: Dihydropyrimidinase -
           Methylobacterium sp. 4-46
          Length = 503

 Score = 53.2 bits (122), Expect = 8e-06
 Identities = 26/61 (42%), Positives = 37/61 (60%)
 Frame = -2

Query: 431 EREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDIT 252
           ERE T   I +A L+D+P+ I HV+  E    I  A+ RGVKV  E CP +L L++ D+ 
Sbjct: 224 EREATHRAIALAELVDQPIQIFHVSCDEAAEEIARARARGVKVWGETCPQYLTLSTEDLA 283

Query: 251 K 249
           +
Sbjct: 284 R 284


>UniRef50_Q7NEQ6 Cluster: Dihydroorotase; n=1; Gloeobacter
           violaceus|Rep: Dihydroorotase - Gloeobacter violaceus
          Length = 407

 Score = 52.8 bits (121), Expect = 1e-05
 Identities = 31/67 (46%), Positives = 38/67 (56%), Gaps = 4/67 (5%)
 Frame = -1

Query: 222 PVLCSPEDQAELWRNIS--IIDVFATDHAPHTVEEKNS--ENPPPGYPGLETILPLLLNA 55
           P L +P D+A L   +   IID  A+DH P T EEK       PPG   LE +LPL+ N 
Sbjct: 279 PPLGNPADRAALVAALEAGIIDAVASDHTPWTYEEKTLPFSQAPPGAIALELVLPLVWNL 338

Query: 54  VHQGRLT 34
           V +GRLT
Sbjct: 339 VREGRLT 345


>UniRef50_Q8KDK5 Cluster: Dihydroorotase; n=10; Chlorobiaceae|Rep:
           Dihydroorotase - Chlorobium tepidum
          Length = 439

 Score = 52.8 bits (121), Expect = 1e-05
 Identities = 20/47 (42%), Positives = 32/47 (68%), Gaps = 1/47 (2%)
 Frame = -2

Query: 374 HICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI-TKLEKG 237
           H+ H++  E + +++ AK  G+KVTCEV PHH  L  +D+ + +EKG
Sbjct: 243 HVAHISTAESVALVRKAKAAGLKVTCEVTPHHFTLTEHDLSSSIEKG 289



 Score = 39.1 bits (87), Expect = 0.14
 Identities = 32/84 (38%), Positives = 41/84 (48%), Gaps = 7/84 (8%)
 Frame = -1

Query: 249 IGKGRAKVCPVLCSPEDQAELWRNI--SIIDVFATDHAPHTVEEKNSENPPP----GYPG 88
           I KG   + P L S E++  L   +    ID  ATDHAPH   EK  E PP     G  G
Sbjct: 286 IEKGNFIMKPPLASVENRDALIEGLRDGTIDAIATDHAPHAKHEK--ECPPDQAAFGIIG 343

Query: 87  LETILPL-LLNAVHQGRLTIEDLL 19
           LET L L +   V +G +T+   +
Sbjct: 344 LETSLGLTITELVDKGVITLSQAI 367


>UniRef50_Q9KAH8 Cluster: Allantoinase; n=1; Bacillus
           halodurans|Rep: Allantoinase - Bacillus halodurans
          Length = 438

 Score = 52.4 bits (120), Expect = 1e-05
 Identities = 22/63 (34%), Positives = 37/63 (58%)
 Frame = -2

Query: 434 AEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 255
           +E E    ++  A L   P+HICHV+ ++ +  IK AK  GV V+ E CPH+L  + ++ 
Sbjct: 219 SELEAVERILRFAQLTCCPIHICHVSSRKVLKRIKQAKGEGVNVSVETCPHYLLFSLDEF 278

Query: 254 TKL 246
            ++
Sbjct: 279 AEI 281



 Score = 38.3 bits (85), Expect = 0.24
 Identities = 26/85 (30%), Positives = 33/85 (38%)
 Frame = -3

Query: 814 PGFIDVHVHVREPGANIKGRF*DLLPQXHWLVVLTMICAMPNTNPSIVDRTAFDYASTLA 635
           PG +DVHVH  EPG      F           V T      N+NP  + R   D    LA
Sbjct: 57  PGMVDVHVHFNEPGRTEWEGFASGSKSLAAGGVTTYFDMPLNSNPPTITREELDKKRQLA 116

Query: 634 RVSARCDYALYVGASSTNYDTICEL 560
              +  DY  + G    N D + +L
Sbjct: 117 NEKSLVDYRFWGGLVPGNIDHLQDL 141


>UniRef50_Q8AB61 Cluster: Dihydroorotase; n=3; Bacteroides|Rep:
           Dihydroorotase - Bacteroides thetaiotaomicron
          Length = 445

 Score = 52.4 bits (120), Expect = 1e-05
 Identities = 31/103 (30%), Positives = 49/103 (47%), Gaps = 3/103 (2%)
 Frame = -3

Query: 817 LPGFIDVHVHVREPGANIKGRF*DLLPQXHWLVV--LTMICAMPNTNPSIVDRTAFDYAS 644
           LPG ID HVH R+PG   K    D+  + H      +T I  MPNTNP      A +   
Sbjct: 55  LPGAIDEHVHFRDPGLTHKA---DITTESHAAAAGGVTSIMDMPNTNPQTTTLEALNDKL 111

Query: 643 TLARVSARCDYALYVGASSTNYDTICEL-APQAAALKMYLNET 518
            L    +  +++ Y GA++ NY    +L   +   +K+++  +
Sbjct: 112 ALLAEKSSVNFSCYFGATNNNYPLFSQLDKNRVCGVKLFMGSS 154



 Score = 43.6 bits (98), Expect = 0.006
 Identities = 27/88 (30%), Positives = 44/88 (50%), Gaps = 4/88 (4%)
 Frame = -1

Query: 255 YKIGKGRAKVCPVLCSPEDQAELWR--NISIIDVFATDHAPHTVEEK--NSENPPPGYPG 88
           Y+    R K  P + + ED+  L    N  +ID  ATDHAPH++ EK   +     G P 
Sbjct: 274 YQTLGARIKCNPAIKTAEDRKALQEAVNSGLIDAIATDHAPHSLSEKEGGALKVMSGMPT 333

Query: 87  LETILPLLLNAVHQGRLTIEDLLCRIRH 4
           ++  L  +L    +G  +IE ++ ++ H
Sbjct: 334 IQFSLVSMLELADKGAFSIEKVVEKMSH 361


>UniRef50_Q2KXE6 Cluster: D-hydantoinase; n=2; Proteobacteria|Rep:
           D-hydantoinase - Bordetella avium (strain 197N)
          Length = 499

 Score = 52.4 bits (120), Expect = 1e-05
 Identities = 26/59 (44%), Positives = 36/59 (61%)
 Frame = -2

Query: 434 AEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSND 258
           AE E T   I ++ LLD PV I HVA  + + II+ A++ G +V  E CP +LFL + D
Sbjct: 225 AESEATHRAIALSRLLDVPVLIVHVAGAQTVDIIRRARQLGAQVYAESCPQYLFLEATD 283


>UniRef50_A4XKT2 Cluster: Dihydroorotase, multifunctional complex
           type; n=1; Caldicellulosiruptor saccharolyticus DSM
           8903|Rep: Dihydroorotase, multifunctional complex type -
           Caldicellulosiruptor saccharolyticus (strain ATCC 43494
           / DSM 8903)
          Length = 430

 Score = 52.4 bits (120), Expect = 1e-05
 Identities = 25/60 (41%), Positives = 35/60 (58%)
 Frame = -2

Query: 434 AEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 255
           AE    A  IL+A      +HI HV+ KE + +IK AKE GV VT + CPH++ L   ++
Sbjct: 210 AESVIIARDILLAKETKSHLHITHVSTKESVRLIKMAKEWGVNVTADTCPHYISLTEEEV 269



 Score = 44.0 bits (99), Expect = 0.005
 Identities = 25/66 (37%), Positives = 31/66 (46%), Gaps = 2/66 (3%)
 Frame = -3

Query: 823 VKLPGFIDVHVHVREPGANIKGRF*DLLPQXHWLVV--LTMICAMPNTNPSIVDRTAFDY 650
           V +P F D+H H+REPG   K    D+            T IC MPNTNP + +R    Y
Sbjct: 52  VVMPSFTDIHCHLREPGFEYKE---DIKSGSRSAAAGGFTTICCMPNTNPPVDNRAMVAY 108

Query: 649 ASTLAR 632
               AR
Sbjct: 109 IKYRAR 114



 Score = 37.1 bits (82), Expect = 0.55
 Identities = 25/61 (40%), Positives = 31/61 (50%), Gaps = 4/61 (6%)
 Frame = -1

Query: 234 AKVCPVLCSPEDQAELWRNIS--IIDVFATDHAPHTVEEKNSE--NPPPGYPGLETILPL 67
           AKV P L + ED   L   +   +ID  +TDHAPH  +EKN E      G  G ET   +
Sbjct: 276 AKVNPPLRTQEDVEALIEGLKEGVIDCISTDHAPHHKDEKNVEFNLAASGTIGFETAFSV 335

Query: 66  L 64
           L
Sbjct: 336 L 336


>UniRef50_O27199 Cluster: Dihydroorotase; n=2; Methanothermobacter
           thermautotrophicus str. Delta H|Rep: Dihydroorotase -
           Methanobacterium thermoautotrophicum
          Length = 431

 Score = 52.4 bits (120), Expect = 1e-05
 Identities = 23/51 (45%), Positives = 33/51 (64%), Gaps = 2/51 (3%)
 Frame = -1

Query: 168 IDVFATDHAPHTVEEKNSE--NPPPGYPGLETILPLLLNAVHQGRLTIEDL 22
           I++  TDHAPH +EEK     + PPG P LE +L LLL  V +GR+++  +
Sbjct: 284 INIIGTDHAPHGIEEKRKGIWDAPPGIPNLEVVLKLLLTLVSKGRMSLSTI 334



 Score = 46.8 bits (106), Expect = 7e-04
 Identities = 22/57 (38%), Positives = 35/57 (61%)
 Frame = -2

Query: 434 AEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNS 264
           AE    A V+ ++   + PVHICH++  + + +++  +E    VTCEV PHHL L+S
Sbjct: 200 AEEVSVAEVLALSIHHEHPVHICHLSTVKALQLVEPFREY---VTCEVTPHHLLLDS 253



 Score = 39.1 bits (87), Expect = 0.14
 Identities = 29/101 (28%), Positives = 45/101 (44%), Gaps = 1/101 (0%)
 Frame = -3

Query: 817 LPGFIDVHVHVREPGANIKGRF-*DLLPQXHWLVVLTMICAMPNTNPSIVDRTAFDYAST 641
           LPG ID HVH R+PG   K  F    +   H     + +  MPNT P   +   F+    
Sbjct: 48  LPGLIDAHVHFRDPGLEYKEDFRTGSMAAAHG--GFSTVLDMPNTVPPADNAAEFERKIR 105

Query: 640 LARVSARCDYALYVGASSTNYDTICELAPQAAALKMYLNET 518
           +    +  D+ L+ G  S + D    L    A+ K++++ T
Sbjct: 106 IGERKSVVDFGLHAGFRSVS-DVKGILRFMPASFKVFMDLT 145


>UniRef50_Q0UHH4 Cluster: Putative uncharacterized protein; n=1;
           Phaeosphaeria nodorum|Rep: Putative uncharacterized
           protein - Phaeosphaeria nodorum (Septoria nodorum)
          Length = 512

 Score = 51.6 bits (118), Expect = 2e-05
 Identities = 24/70 (34%), Positives = 41/70 (58%)
 Frame = -2

Query: 434 AEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 255
           AE E +   I +A L+D P+ I H++ +  +  ++AA+ R + V  E CPH+LFL S +I
Sbjct: 225 AEDEASYRAISLAELVDAPILIVHMSSEAAVEHVRAAQARLLPVHAETCPHYLFLLSEEI 284

Query: 254 TKLEKGEQKY 225
            +   G+  +
Sbjct: 285 KQCHHGDNSH 294


>UniRef50_O66990 Cluster: Dihydroorotase; n=1; Aquifex aeolicus|Rep:
           Dihydroorotase - Aquifex aeolicus
          Length = 422

 Score = 51.6 bits (118), Expect = 2e-05
 Identities = 31/75 (41%), Positives = 43/75 (57%), Gaps = 3/75 (4%)
 Frame = -1

Query: 234 AKVCPVLCSPEDQAELWRNIS--IIDVFATDHAPH-TVEEKNSENPPPGYPGLETILPLL 64
           A+V P L   ED+  L   +   IID FATDHAPH T E++  E   PG  GL+T LP  
Sbjct: 275 ARVNPPLRKKEDRLALIEGVKRGIIDCFATDHAPHQTFEKELVEFAMPGIIGLQTALPSA 334

Query: 63  LNAVHQGRLTIEDLL 19
           L    +G ++++ L+
Sbjct: 335 LELYRKGIISLKKLI 349



 Score = 47.6 bits (108), Expect = 4e-04
 Identities = 24/60 (40%), Positives = 35/60 (58%)
 Frame = -2

Query: 434 AEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 255
           AE  + A   ++A      VHI HV+ K  + II+  KE+GVK+TCEV P+HL     ++
Sbjct: 209 AEEIQIARDGILAQRTGGHVHIQHVSTKLSLEIIEFFKEKGVKITCEVNPNHLLFTEREV 268



 Score = 46.4 bits (105), Expect = 9e-04
 Identities = 25/61 (40%), Positives = 33/61 (54%), Gaps = 2/61 (3%)
 Frame = -3

Query: 826 IVKLPGFIDVHVHVREPGANIKGRF*DLLPQXHWLVV--LTMICAMPNTNPSIVDRTAFD 653
           ++  PGFID+HVH+R+PG   K    D+       V    T I  MPNTNP I + T  +
Sbjct: 51  LIVCPGFIDIHVHLRDPGQTYKE---DIESGSRCAVAGGFTTIVCMPNTNPPIDNTTVVN 107

Query: 652 Y 650
           Y
Sbjct: 108 Y 108


>UniRef50_A6TVS5 Cluster: Dihydroorotase; n=8; Clostridiales|Rep:
           Dihydroorotase - Alkaliphilus metalliredigens QYMF
          Length = 429

 Score = 51.2 bits (117), Expect = 3e-05
 Identities = 24/62 (38%), Positives = 35/62 (56%)
 Frame = -2

Query: 434 AEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 255
           AE    A  I++A      +H+CHV+ K  + + + AK+RG  VT EVCPHH  L  + +
Sbjct: 209 AEEVIIARDIILARNTGVKLHLCHVSTKGGVELTREAKQRGENVTAEVCPHHFALTEDIV 268

Query: 254 TK 249
            K
Sbjct: 269 EK 270



 Score = 41.9 bits (94), Expect = 0.019
 Identities = 23/50 (46%), Positives = 29/50 (58%)
 Frame = -3

Query: 817 LPGFIDVHVHVREPGANIKGRF*DLLPQXHWLVVLTMICAMPNTNPSIVD 668
           +PG IDVHVH+REPG   K    +   +   +   T IC MPNT P +VD
Sbjct: 53  VPGLIDVHVHLREPGFEHKETI-ETGSKSAAMGGFTTICCMPNTQP-VVD 100



 Score = 41.1 bits (92), Expect = 0.034
 Identities = 25/60 (41%), Positives = 34/60 (56%), Gaps = 4/60 (6%)
 Frame = -1

Query: 234 AKVCPVLCSPEDQAELWRNI--SIIDVFATDHAPHTVEEKNSE--NPPPGYPGLETILPL 67
           +K+ P L + ED   + + +    I+V ATDHAPH  +EKN E    P G  GLET L +
Sbjct: 275 SKMNPPLRTGEDVDAIKQGLVDGTIEVIATDHAPHHADEKNQEFHQAPFGIVGLETALSI 334


>UniRef50_A7D6W5 Cluster: Amidohydrolase; n=1; Halorubrum
           lacusprofundi ATCC 49239|Rep: Amidohydrolase -
           Halorubrum lacusprofundi ATCC 49239
          Length = 463

 Score = 51.2 bits (117), Expect = 3e-05
 Identities = 28/76 (36%), Positives = 45/76 (59%), Gaps = 6/76 (7%)
 Frame = -1

Query: 237 RAKVCPVLCSPEDQAELWRNIS--IIDVFATDHAPHTVEEKNSENPP---PGYPGLETIL 73
           R  V P + S EDQ  LW+ ++   I    TDH  +  ++K  E+ P   PG+P   T+L
Sbjct: 293 RHNVNPPVRSKEDQETLWKRVADGTISCIGTDHCANLRDDKVGEDVPDSLPGFPSTATML 352

Query: 72  PLLLN-AVHQGRLTIE 28
           PL+L+  V++GR+++E
Sbjct: 353 PLILSEGVNEGRISLE 368


>UniRef50_A5DGE8 Cluster: Putative uncharacterized protein; n=1;
           Pichia guilliermondii|Rep: Putative uncharacterized
           protein - Pichia guilliermondii (Yeast) (Candida
           guilliermondii)
          Length = 378

 Score = 50.8 bits (116), Expect = 4e-05
 Identities = 23/62 (37%), Positives = 35/62 (56%)
 Frame = -2

Query: 431 EREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDIT 252
           E E T   I+M+  +D PV   HV+  E I  I+ A+ RG+ V  E CP +L L + D+ 
Sbjct: 103 EGEATNRAIVMSEAMDSPVLFVHVSAPEAIRSIREARSRGLSVFAETCPQYLLLKAEDLK 162

Query: 251 KL 246
           ++
Sbjct: 163 RI 164


>UniRef50_Q6AF87 Cluster: Dihydroorotase; n=9; Actinobacteria
           (class)|Rep: Dihydroorotase - Leifsonia xyli subsp. xyli
          Length = 438

 Score = 50.8 bits (116), Expect = 4e-05
 Identities = 23/55 (41%), Positives = 33/55 (60%)
 Frame = -2

Query: 434 AEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFL 270
           AE    A  +L+A  +   +H+CHV+    + +I+ AK RG+ VT EV PHHL L
Sbjct: 209 AEESIIARDVLLAEHVGSRLHVCHVSTAGSVDVIRWAKARGIDVTAEVTPHHLLL 263



 Score = 39.1 bits (87), Expect = 0.14
 Identities = 27/66 (40%), Positives = 36/66 (54%), Gaps = 4/66 (6%)
 Frame = -1

Query: 237 RAKVCPVLCSPEDQAELWRNIS--IIDVFATDHAPHTVEEKNSENPPP--GYPGLETILP 70
           R KV P L   ED   L   ++   ID+ ATDHAPH VE K+ E      G  GLE+ L 
Sbjct: 274 RYKVNPPLRRSEDVEALRAGLADGTIDIVATDHAPHPVEAKDCEWDAAAFGMVGLESALS 333

Query: 69  LLLNAV 52
           ++ ++V
Sbjct: 334 VVQSSV 339


>UniRef50_Q1M4X9 Cluster: Putative D-hydantoinase; n=1; Rhizobium
           leguminosarum bv. viciae 3841|Rep: Putative
           D-hydantoinase - Rhizobium leguminosarum bv. viciae
           (strain 3841)
          Length = 477

 Score = 50.4 bits (115), Expect = 6e-05
 Identities = 22/59 (37%), Positives = 36/59 (61%)
 Frame = -2

Query: 431 EREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 255
           +RE T   I ++ L++ P+ + HVA    +  I+ AK RG+ +  E CP +LFL++ DI
Sbjct: 222 DREATFRAISLSELIETPILVSHVAAGGAVEEIRRAKARGLPIYAETCPQYLFLSAEDI 280



 Score = 35.1 bits (77), Expect = 2.2
 Identities = 26/82 (31%), Positives = 42/82 (51%), Gaps = 11/82 (13%)
 Frame = -1

Query: 240 GRAKVC-PVLCSPEDQAELWRNI--SIIDVFATDHAPHTVEEKNSENP-------PPGYP 91
           G   VC P      +Q  +W  I    ++VF++DH+P    +K +  P       P G P
Sbjct: 287 GSKCVCTPPPRDKSNQPAIWAGILDGTLEVFSSDHSPWHYADKIAGGPGTPFHRIPNGIP 346

Query: 90  GLETILPLLLNA-VHQGRLTIE 28
           G+ET L LL +A V+ G ++++
Sbjct: 347 GIETRLALLFSAGVNGGLISLQ 368


>UniRef50_Q18ZN3 Cluster: Dihydroorotase; n=3; Clostridiales|Rep:
           Dihydroorotase - Desulfitobacterium hafniense (strain
           DCB-2)
          Length = 434

 Score = 50.4 bits (115), Expect = 6e-05
 Identities = 23/66 (34%), Positives = 35/66 (53%)
 Frame = -2

Query: 434 AEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 255
           +E    A  IL+A      +H+ H++ KE + +I+  K+RGV VT EV PHHL      +
Sbjct: 217 SESVMVARDILLAEESGGKLHLAHISAKESVALIREGKKRGVDVTAEVNPHHLLFTDEAV 276

Query: 254 TKLEKG 237
            +   G
Sbjct: 277 ARTPYG 282



 Score = 44.0 bits (99), Expect = 0.005
 Identities = 32/76 (42%), Positives = 40/76 (52%), Gaps = 5/76 (6%)
 Frame = -1

Query: 231 KVCPVLCSPEDQAELWRNI--SIIDVFATDHAPHTVEEKNS--ENPPPGYPGLETILPLL 64
           KV P L   ED+  L   +    +D+ ATDHAPHT EEK +  +  P G  GLET L  +
Sbjct: 286 KVNPPLRREEDRQALIEGLLDGTLDMLATDHAPHTWEEKTNPFDQAPFGISGLETALAAV 345

Query: 63  -LNAVHQGRLTIEDLL 19
               V  G L IE L+
Sbjct: 346 WQELVTTGILPIELLI 361



 Score = 38.3 bits (85), Expect = 0.24
 Identities = 23/57 (40%), Positives = 28/57 (49%), Gaps = 2/57 (3%)
 Frame = -3

Query: 814 PGFIDVHVHVREPGANIKGRF*DLLPQXHWLV--VLTMICAMPNTNPSIVDRTAFDY 650
           PG IDVH H+REPG   K    D+       V    T I AMPNT P +  +   +Y
Sbjct: 62  PGLIDVHTHLREPGREDKE---DIASGSRAAVRGGFTTILAMPNTTPILDQKALVEY 115


>UniRef50_Q9RVC3 Cluster: Dihydroorotase; n=5; Deinococci|Rep:
           Dihydroorotase - Deinococcus radiodurans
          Length = 416

 Score = 50.4 bits (115), Expect = 6e-05
 Identities = 22/60 (36%), Positives = 35/60 (58%)
 Frame = -2

Query: 434 AEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 255
           A   + A  + + +L    +H+ H++   E+ I++ AK RG+ VTCEVCPHHL L    +
Sbjct: 202 AAAARVARDMEIVALTGARLHVQHLSTARELDIVRDAKRRGLPVTCEVCPHHLDLTDESL 261



 Score = 35.9 bits (79), Expect = 1.3
 Identities = 25/75 (33%), Positives = 36/75 (48%), Gaps = 4/75 (5%)
 Frame = -1

Query: 231 KVCPVLCSPEDQAELWRNI--SIIDVFATDHAPHTVEEKNSE--NPPPGYPGLETILPLL 64
           KV P L +  D   L   +    +D  ATDHAPHT  EK  +  + P G   +E   P++
Sbjct: 269 KVAPPLRTRADADYLLEGLLDGSVDCIATDHAPHTRAEKERDLLDAPSGIAYIEIAFPIM 328

Query: 63  LNAVHQGRLTIEDLL 19
                + RL +E L+
Sbjct: 329 WTRFGE-RLGLEKLI 342


>UniRef50_Q3AEA1 Cluster: Allantoinase; n=3; Clostridiales|Rep:
           Allantoinase - Carboxydothermus hydrogenoformans (strain
           Z-2901 / DSM 6008)
          Length = 471

 Score = 50.0 bits (114), Expect = 7e-05
 Identities = 28/81 (34%), Positives = 48/81 (59%), Gaps = 9/81 (11%)
 Frame = -1

Query: 234 AKVCPVLCSPEDQAELWRNISI--IDVFATDHAPHTVE-EKNSENPP-----PGYPGLET 79
           AK+ P L +  D   LW  ++   +D  ATDHAP+ +  EK +E        PG PG+ET
Sbjct: 288 AKIAPPLRTTRDNEMLWEQLADGRVDFIATDHAPYEIATEKEAEGMDIWTAFPGIPGVET 347

Query: 78  ILPLLLN-AVHQGRLTIEDLL 19
           ++P++++   ++GRL++  L+
Sbjct: 348 MVPIIISEGYNKGRLSLSRLV 368



 Score = 40.7 bits (91), Expect = 0.045
 Identities = 20/57 (35%), Positives = 31/57 (54%)
 Frame = -2

Query: 434 AEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNS 264
           AE+      I  A      +HI H++     +++  AK+RG+ VT E CPH+L LN+
Sbjct: 221 AEKVAIQMAISFAEETGARLHIVHMSTGIGGVLVGEAKKRGLDVTAETCPHYLVLNA 277


>UniRef50_A6P0Z6 Cluster: Dihydroorotase; n=1; Bacteroides
           capillosus ATCC 29799|Rep: Dihydroorotase - Bacteroides
           capillosus ATCC 29799
          Length = 427

 Score = 50.0 bits (114), Expect = 7e-05
 Identities = 22/66 (33%), Positives = 37/66 (56%)
 Frame = -2

Query: 434 AEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 255
           AE  +     ++A      VHICH++  + + I++  K +GV++TCE CP +  L  ++I
Sbjct: 209 AEELQVMRDAMLAEETGAAVHICHISTAKSVAIVRRYKRKGVQITCETCPQYFSLTEDEI 268

Query: 254 TKLEKG 237
             L KG
Sbjct: 269 --LTKG 272



 Score = 47.2 bits (107), Expect = 5e-04
 Identities = 25/53 (47%), Positives = 31/53 (58%), Gaps = 3/53 (5%)
 Frame = -1

Query: 168 IDVFATDHAPHTVEEKNS--ENPPPGYPGLETILPLLLNAV-HQGRLTIEDLL 19
           ID  ATDHAPH+ EEK       P G  GLET L + L A+ H G + + D+L
Sbjct: 299 IDAIATDHAPHSAEEKGRPLTEAPSGMVGLETALGVTLTALYHTGEMGLSDIL 351


>UniRef50_A3H6L5 Cluster: Amidohydrolase; n=1; Caldivirga
           maquilingensis IC-167|Rep: Amidohydrolase - Caldivirga
           maquilingensis IC-167
          Length = 407

 Score = 50.0 bits (114), Expect = 7e-05
 Identities = 30/68 (44%), Positives = 40/68 (58%), Gaps = 5/68 (7%)
 Frame = -1

Query: 231 KVCPVLCSPEDQAELWRNI--SIIDVFATDHAPHTVEEK---NSENPPPGYPGLETILPL 67
           KV P L S   + EL R +    I + A+DHAPHT+ EK   N ++  PG+PGLET   L
Sbjct: 243 KVNPPLRSKSIRFELLRRLIDGSISIIASDHAPHTISEKFHNNYDDTSPGFPGLETTGLL 302

Query: 66  LLNAVHQG 43
           LL+   +G
Sbjct: 303 LLDLWRRG 310


>UniRef50_Q8R9R6 Cluster: Dihydroorotase; n=5; Clostridia|Rep:
           Dihydroorotase - Thermoanaerobacter tengcongensis
          Length = 431

 Score = 50.0 bits (114), Expect = 7e-05
 Identities = 23/53 (43%), Positives = 31/53 (58%)
 Frame = -2

Query: 434 AEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHL 276
           AE    A  I++A      +HI HV+ K  + +I+ AKE GV +T EV PHHL
Sbjct: 208 AEEVMLARNIILAKATGAKLHIAHVSTKGSVELIRRAKEEGVSITAEVTPHHL 260



 Score = 41.9 bits (94), Expect = 0.019
 Identities = 21/62 (33%), Positives = 30/62 (48%)
 Frame = -3

Query: 817 LPGFIDVHVHVREPGANIKGRF*DLLPQXHWLVVLTMICAMPNTNPSIVDRTAFDYASTL 638
           LPGF+D+H H+R+PG   K        +       T +  MPNTNP I      +Y   +
Sbjct: 52  LPGFVDMHTHLRQPGFEEKETI-RTGTESAAAGGFTTVACMPNTNPPIDSEVVVEYVKAV 110

Query: 637 AR 632
           A+
Sbjct: 111 AQ 112



 Score = 38.7 bits (86), Expect = 0.18
 Identities = 27/76 (35%), Positives = 39/76 (51%), Gaps = 5/76 (6%)
 Frame = -1

Query: 231 KVCPVLCSPEDQAELWRNIS--IIDVFATDHAPHTVEEKN--SENPPPGYPGLETILPLL 64
           KV P L + ED   L   +    ID  ATDHAPHT ++K    +  P G  GLET   ++
Sbjct: 275 KVFPPLRTREDVEALIEGLKDGTIDAIATDHAPHTKDDKKVPYDMAPFGISGLETAFSVI 334

Query: 63  LN-AVHQGRLTIEDLL 19
               +  G +T++ L+
Sbjct: 335 NTFLIQTGIITMKALV 350


>UniRef50_A7CWA7 Cluster: Dihydroorotase, multifunctional complex
           type; n=1; Opitutaceae bacterium TAV2|Rep:
           Dihydroorotase, multifunctional complex type -
           Opitutaceae bacterium TAV2
          Length = 433

 Score = 49.6 bits (113), Expect = 1e-04
 Identities = 31/83 (37%), Positives = 46/83 (55%), Gaps = 8/83 (9%)
 Frame = -1

Query: 237 RAKVCPVLCSPEDQAELWRNI--SIIDVFATDHAPHTVEEKNSE--NPPPGYPGLETILP 70
           R K+ P L + +D+  +   +    +D+ ATDHAPHT +EK+ E    P G  GLET LP
Sbjct: 276 RFKMNPPLRTEDDRLAIIEGLRDGTLDIIATDHAPHTDDEKDKEFDYAPNGIIGLETSLP 335

Query: 69  LLLNAVHQGR----LTIEDLLCR 13
           + L  +H+       T+ DL+ R
Sbjct: 336 ISLEILHRQNKFKLATVIDLMTR 358



 Score = 39.9 bits (89), Expect = 0.078
 Identities = 17/46 (36%), Positives = 27/46 (58%)
 Frame = -2

Query: 407 ILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFL 270
           +++A+     +H+ H++    + II+ AK RGV VT E  PHH  L
Sbjct: 220 VILATYTGARIHMQHISSHNAVDIIRRAKTRGVPVTAEGTPHHFAL 265



 Score = 35.9 bits (79), Expect = 1.3
 Identities = 18/49 (36%), Positives = 25/49 (51%)
 Frame = -3

Query: 826 IVKLPGFIDVHVHVREPGANIKGRF*DLLPQXHWLVVLTMICAMPNTNP 680
           +V  PG +D+HVH REPG   K    +   +       T +  MPNT+P
Sbjct: 51  LVAAPGLVDIHVHFREPGQTHKETI-ETGSRAAAAGGFTSVVCMPNTSP 98


>UniRef50_Q97LN7 Cluster: Dihydroorotase; n=4; Clostridiales|Rep:
           Dihydroorotase - Clostridium acetobutylicum
          Length = 424

 Score = 49.6 bits (113), Expect = 1e-04
 Identities = 33/80 (41%), Positives = 43/80 (53%), Gaps = 5/80 (6%)
 Frame = -1

Query: 234 AKVCPVLCSPEDQAELWRNIS--IIDVFATDHAPHTVEEKNSE--NPPPGYPGLETILPL 67
           AKV P L   +D+  +   +    I V ATDHAPHT +EK  E    P G  GLET L L
Sbjct: 274 AKVNPPLRREDDRKAIVAALKDDTIQVIATDHAPHTKDEKAREFKEAPSGMIGLETALSL 333

Query: 66  -LLNAVHQGRLTIEDLLCRI 10
            + N V  G LT  D++ ++
Sbjct: 334 AVTNLVKTGDLTYRDMISKL 353



 Score = 34.7 bits (76), Expect = 2.9
 Identities = 20/66 (30%), Positives = 28/66 (42%)
 Frame = -2

Query: 452 MPVCTHAEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLF 273
           M     AE   TA    +A       +I H++ K  + IIK AKE G  +  E  P H  
Sbjct: 202 MGALEEAETVLTARDAALAVSSGAKTNIQHISSKISLGIIKLAKEMGANIIAEATPQHFS 261

Query: 272 LNSNDI 255
           +   +I
Sbjct: 262 ITEEEI 267


>UniRef50_A4GK51 Cluster: Dihydroorotase; n=1; uncultured marine
           bacterium HF130_81H07|Rep: Dihydroorotase - uncultured
           marine bacterium HF130_81H07
          Length = 444

 Score = 49.2 bits (112), Expect = 1e-04
 Identities = 34/104 (32%), Positives = 48/104 (46%), Gaps = 2/104 (1%)
 Frame = -3

Query: 814 PGFIDVHVHVREPGANIKGRF*-DLLPQXHWLVVLTMICAMPNTNPSIVDRTAFDYASTL 638
           PG ID  VH R+PG   KG    + L   H  V  T    MPN NP+          + L
Sbjct: 54  PGIIDDQVHFRDPGLTEKGDIRSESLAAVHGGVTSTF--DMPNVNPNTTTIELMSARNKL 111

Query: 637 ARVSARCDYALYVGASSTNYDTICELAP-QAAALKMYLNETFTT 509
               +  +YA Y GA+ TN + I +L P +   LK+++  +  T
Sbjct: 112 GAEKSWTNYAYYFGATETNIEEIKKLDPKEICGLKVFMGTSTGT 155



 Score = 42.7 bits (96), Expect = 0.011
 Identities = 27/101 (26%), Positives = 44/101 (43%)
 Frame = -2

Query: 548 CSSKDVLK*NFYNFLLEDMTIWQKHFQSWPKKMPVCTHAEREKTAAVILMASLLDRPVHI 369
           C   + +K N     LE+  I    F    K   +C +    K   VI +A      +H+
Sbjct: 179 CEDNETMKNNLERVKLENAEI-DASFHPIIKD-DICCYRSSSK---VINLAKKYSSDLHV 233

Query: 368 CHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDITKL 246
            H+  ++EI +      +   +TCEVC HHL+ +  D  +L
Sbjct: 234 LHLTTEKEIELFTNDPVKDKNITCEVCVHHLWFDERDYKEL 274



 Score = 37.9 bits (84), Expect = 0.31
 Identities = 25/82 (30%), Positives = 39/82 (47%), Gaps = 9/82 (10%)
 Frame = -1

Query: 219 VLCSPEDQAELWRNI-------SIIDVFATDHAPHTVEEKNSE--NPPPGYPGLETILPL 67
           ++C+P  + E  RN          ID  ATDHAPH  EEK         G P +E    +
Sbjct: 278 IVCNPAIKKESDRNALRKALKDGFIDYVATDHAPHVYEEKLRPYLQASAGIPLIEHSFHI 337

Query: 66  LLNAVHQGRLTIEDLLCRIRHE 1
           ++    QG  +IE+++  + H+
Sbjct: 338 MMELQKQGVYSIEEVVAFMSHK 359


>UniRef50_A0RQX7 Cluster: Dihydroorotase; n=4; Campylobacter|Rep:
           Dihydroorotase - Campylobacter fetus subsp. fetus
           (strain 82-40)
          Length = 426

 Score = 49.2 bits (112), Expect = 1e-04
 Identities = 30/76 (39%), Positives = 42/76 (55%), Gaps = 5/76 (6%)
 Frame = -1

Query: 231 KVCPVLCSPEDQAELWRN---ISIIDVFATDHAPHTVEEK--NSENPPPGYPGLETILPL 67
           K+ P L +  D  E  RN     +IDV  TDHAPH  +EK    +  P G  GL+T++PL
Sbjct: 273 KMSPPLRTNND-VEAMRNGLKNGLIDVICTDHAPHHTDEKFLEFDKAPFGILGLQTLVPL 331

Query: 66  LLNAVHQGRLTIEDLL 19
            LN V +G +  E ++
Sbjct: 332 TLNLVREGVIDYEQMV 347



 Score = 48.0 bits (109), Expect = 3e-04
 Identities = 18/51 (35%), Positives = 31/51 (60%)
 Frame = -2

Query: 407 ILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 255
           +L+A L    +H+ HV+    + +I+ AK  GV +TCEV PHH   + +++
Sbjct: 215 MLLAKLTGGHIHVAHVSSAYSLKLIEQAKNEGVNITCEVTPHHFTFSEDEL 265



 Score = 38.3 bits (85), Expect = 0.24
 Identities = 21/52 (40%), Positives = 28/52 (53%), Gaps = 2/52 (3%)
 Frame = -3

Query: 829 NIVKLPGFIDVHVHVREPGANIKGRF*DLLPQXHWLVV--LTMICAMPNTNP 680
           N + +PG ID+HVH R+PG   K    D++      V   +T  C M NTNP
Sbjct: 46  NKLVMPGLIDMHVHFRDPGLEYKD---DIITGSMSAVAGGVTTACPMANTNP 94


>UniRef50_UPI00015BB20A Cluster: dihydroorotase; n=1; Ignicoccus
           hospitalis KIN4/I|Rep: dihydroorotase - Ignicoccus
           hospitalis KIN4/I
          Length = 383

 Score = 48.8 bits (111), Expect = 2e-04
 Identities = 23/50 (46%), Positives = 32/50 (64%), Gaps = 2/50 (4%)
 Frame = -1

Query: 162 VFATDHAPHTVEEKNSE--NPPPGYPGLETILPLLLNAVHQGRLTIEDLL 19
           +  TDHAPH V EK     + PPG+PGLET LPLLL    +G +++  ++
Sbjct: 254 MMVTDHAPHAVWEKELPFYDCPPGFPGLETALPLLLTLYKRGIISLNKVV 303


>UniRef50_Q8F061 Cluster: Dihydroorotase; n=5; Bacteria|Rep:
           Dihydroorotase - Leptospira interrogans
          Length = 424

 Score = 48.8 bits (111), Expect = 2e-04
 Identities = 29/87 (33%), Positives = 43/87 (49%)
 Frame = -2

Query: 512 NFLLEDMTIWQKHFQSWPKKMPVCTHAEREKTAAVILMASLLDRPVHICHVARKEEILII 333
           +F  ED  I +KH      +      AE   T   + +    +    +CH +  E +  I
Sbjct: 181 SFHCEDPEILEKHQNETFHEDRRPAEAETTATDFALYLIEKYNLRGKLCHYSTGEGLNKI 240

Query: 332 KAAKERGVKVTCEVCPHHLFLNSNDIT 252
           K AK++GVKVTCEV P HLF + + +T
Sbjct: 241 KFAKQKGVKVTCEVTPTHLFFDRSMLT 267



 Score = 35.1 bits (77), Expect = 2.2
 Identities = 17/36 (47%), Positives = 22/36 (61%), Gaps = 2/36 (5%)
 Frame = -1

Query: 222 PVLCSPEDQAELWRNISI--IDVFATDHAPHTVEEK 121
           P L S ED+  +   +    ID  ATDHAPH++EEK
Sbjct: 278 PPLRSKEDRERMLEGVKQGWIDYLATDHAPHSIEEK 313


>UniRef50_Q83HU2 Cluster: Dihydroorotase; n=2; Tropheryma
           whipplei|Rep: Dihydroorotase - Tropheryma whipplei
           (strain TW08/27) (Whipple's bacillus)
          Length = 428

 Score = 48.8 bits (111), Expect = 2e-04
 Identities = 23/53 (43%), Positives = 31/53 (58%)
 Frame = -2

Query: 434 AEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHL 276
           AE    A  IL+A   +  +H+CHV+ +E +  I   K  GV+VT EV PHHL
Sbjct: 215 AESTIVARDILLARAANARLHVCHVSSQESVYAIAWGKSLGVQVTAEVTPHHL 267



 Score = 37.9 bits (84), Expect = 0.31
 Identities = 29/75 (38%), Positives = 37/75 (49%), Gaps = 4/75 (5%)
 Frame = -1

Query: 246 GKGRAKVCPVLCSPEDQAELWRNI---SIIDVFATDHAPHTVEEKNSENPPPGYPGLETI 76
           G  R KV P L S E   E  R+     +IDV ATDHAPH  +     + P G  GLE  
Sbjct: 277 GDTRFKVNPPLRSKES-VECLRDALIRGVIDVVATDHAPHRNKSPFWHSAPNGMTGLEFS 335

Query: 75  LPLLLNA-VHQGRLT 34
           + ++    V+ G LT
Sbjct: 336 VSVIQKIFVNSGHLT 350


>UniRef50_Q765R4 Cluster: Allantoinase; n=1; Klebsiella
           pneumoniae|Rep: Allantoinase - Klebsiella pneumoniae
          Length = 336

 Score = 48.8 bits (111), Expect = 2e-04
 Identities = 22/68 (32%), Positives = 38/68 (55%)
 Frame = -2

Query: 449 PVCTHAEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFL 270
           PV T  E E    V+ +A +    +H+CHV+  E +  +  A++ G  VTCE CPH+  L
Sbjct: 229 PVFT--EVEAIRRVLYLAKVAGCRLHVCHVSSPEGVAEVTRARQEGQDVTCESCPHYFVL 286

Query: 269 NSNDITKL 246
           +++   ++
Sbjct: 287 DTDQFAEI 294



 Score = 34.3 bits (75), Expect = 3.9
 Identities = 25/89 (28%), Positives = 35/89 (39%)
 Frame = -3

Query: 826 IVKLPGFIDVHVHVREPGANIKGRF*DLLPQXHWLVVLTMICAMPNTNPSIVDRTAFDYA 647
           ++  PG +D H H+ EPG      +           + TMI    N  P+ VDR   +  
Sbjct: 62  LIVSPGMVDAHTHISEPGRTHWEGYETGTRAAAKGGITTMIEMPLNQLPATVDRQTIELK 121

Query: 646 STLARVSARCDYALYVGASSTNYDTICEL 560
              A+     D A   G  S N D + EL
Sbjct: 122 FDAAKGKLTIDAAQLGGLVSYNLDRLHEL 150


>UniRef50_Q18S75 Cluster: Amidohydrolase; n=2; Desulfitobacterium
           hafniense|Rep: Amidohydrolase - Desulfitobacterium
           hafniense (strain DCB-2)
          Length = 452

 Score = 48.8 bits (111), Expect = 2e-04
 Identities = 29/84 (34%), Positives = 38/84 (45%)
 Frame = -2

Query: 500 EDMTIWQKHFQSWPKKMPVCTHAEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAK 321
           +D   WQ    S P        AE   T  +I +A  +   VHICHV+      II+ A+
Sbjct: 199 KDTNDWQDFLDSRP------VIAELIATQNIIDLAKEVGAKVHICHVSHPRVAEIIRQAQ 252

Query: 320 ERGVKVTCEVCPHHLFLNSNDITK 249
             GV VT E C H+L     D+ K
Sbjct: 253 NEGVDVTAETCGHYLTFTDQDVVK 276


>UniRef50_A6R6Y6 Cluster: Allantoinase; n=1; Ajellomyces capsulatus
           NAm1|Rep: Allantoinase - Ajellomyces capsulatus NAm1
          Length = 592

 Score = 48.8 bits (111), Expect = 2e-04
 Identities = 22/60 (36%), Positives = 37/60 (61%), Gaps = 1/60 (1%)
 Frame = -2

Query: 431 EREKTAAVILMASLLDR-PVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 255
           E    +A++ +A L    P+HI H++  E I ++KAA+ RGV +T E C H+L L + ++
Sbjct: 254 ETTAISAILSLAPLAPNLPLHIVHLSAMEAIPLLKAARRRGVNITAETCFHYLSLTAEEV 313


>UniRef50_Q97QN4 Cluster: Dihydroorotase; n=47; Firmicutes|Rep:
           Dihydroorotase - Streptococcus pneumoniae
          Length = 422

 Score = 48.8 bits (111), Expect = 2e-04
 Identities = 33/78 (42%), Positives = 43/78 (55%), Gaps = 6/78 (7%)
 Frame = -1

Query: 234 AKVCPVLCSPEDQAELWRNIS--IIDVFATDHAPHTVEEKNSEN---PPPGYPGLETILP 70
           AK+ P L    D+  +   +   +I V ATDHAPH V+EKN E+    P G  GLET L 
Sbjct: 273 AKMNPPLRLESDRRAVIEGLKSGVITVIATDHAPHHVDEKNVEDITKAPSGMTGLETSLS 332

Query: 69  LLLN-AVHQGRLTIEDLL 19
           L L   V  G L++ +LL
Sbjct: 333 LSLTYLVEAGELSLMELL 350



 Score = 37.9 bits (84), Expect = 0.31
 Identities = 17/52 (32%), Positives = 30/52 (57%)
 Frame = -2

Query: 434 AEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHH 279
           AE    A  +++A      VHI H++++E + +++ A+  G +VT EV P H
Sbjct: 207 AEYAMMARDVMIAYATKAHVHIQHLSKEESVKVVEFAQGLGAEVTAEVAPQH 258



 Score = 33.1 bits (72), Expect = 8.9
 Identities = 20/55 (36%), Positives = 27/55 (49%), Gaps = 2/55 (3%)
 Frame = -3

Query: 826 IVKLPGFIDVHVHVREPGANIKGRF*DLLPQXHWLVV--LTMICAMPNTNPSIVD 668
           +V  PG +D+HVH REPG   K    D+            T +  M NT+P+I D
Sbjct: 49  LVVAPGLVDIHVHFREPGQTHKE---DIHTGALAAAAGGFTTVVMMANTSPTISD 100


>UniRef50_Q8TSA6 Cluster: Dihydroorotase; n=4;
           Methanosarcinaceae|Rep: Dihydroorotase - Methanosarcina
           acetivorans
          Length = 467

 Score = 48.8 bits (111), Expect = 2e-04
 Identities = 23/56 (41%), Positives = 35/56 (62%), Gaps = 2/56 (3%)
 Frame = -1

Query: 180 NISIIDVFATDHAPHTVEEKNSE--NPPPGYPGLETILPLLLNAVHQGRLTIEDLL 19
           N   ID+ A+DHAPH   EK+ +    P G PG+ET++PL+L AV +  L +  ++
Sbjct: 303 NDGTIDMVASDHAPHLESEKDLDIRAAPSGVPGVETLMPLMLAAVRKNILPLSQMI 358



 Score = 43.6 bits (98), Expect = 0.006
 Identities = 30/86 (34%), Positives = 42/86 (48%)
 Frame = -3

Query: 817 LPGFIDVHVHVREPGANIKGRF*DLLPQXHWLVVLTMICAMPNTNPSIVDRTAFDYASTL 638
           LP  IDVHVH REPG  +K  +           + T+I   PNT P   DR +F+    L
Sbjct: 53  LPAGIDVHVHFREPGMTLKENWYTGSCAAAAGGIATVI-DQPNTIPPTTDRRSFEQKLKL 111

Query: 637 ARVSARCDYALYVGASSTNYDTICEL 560
           AR  +  D+ +  G +  N + + EL
Sbjct: 112 ARKKSIVDFGINGGVTG-NIEKLREL 136



 Score = 39.1 bits (87), Expect = 0.14
 Identities = 23/68 (33%), Positives = 34/68 (50%), Gaps = 6/68 (8%)
 Frame = -2

Query: 431 EREKTAAVILMASLLDRPVHICHVARKEEILIIKA----AKERGVK--VTCEVCPHHLFL 270
           E     + + + S L    H CH++  E + +I+     AK    K   TCEV PHHLFL
Sbjct: 212 EASAVQSALELISRLQVRAHFCHLSTLEAVGMIRKEKYLAKRENKKPLFTCEVTPHHLFL 271

Query: 269 NSNDITKL 246
           ++ D  +L
Sbjct: 272 SAKDWERL 279


>UniRef50_Q64RK7 Cluster: Dihydroorotase; n=6; Bacteroidales|Rep:
           Dihydroorotase - Bacteroides fragilis
          Length = 459

 Score = 48.4 bits (110), Expect = 2e-04
 Identities = 30/103 (29%), Positives = 47/103 (45%), Gaps = 3/103 (2%)
 Frame = -3

Query: 817 LPGFIDVHVHVREPGANIKGRF*DLLPQXHWLVV--LTMICAMPNTNPSIVDRTAFDYAS 644
           +PG ID HVH R+PG   K    D+  +        +T I  MPNTNP      A +   
Sbjct: 55  IPGVIDDHVHFRDPGLTHKA---DISTESRAAAAGGVTSIMDMPNTNPQTTTLDALNAKF 111

Query: 643 TLARVSARCDYALYVGASSTNYDTICEL-APQAAALKMYLNET 518
            L       +Y+ Y GA++ NY    +L   +   +K+++  +
Sbjct: 112 DLLAEKCSVNYSCYFGATNNNYTEFDKLDKNRVCGIKLFMGSS 154



 Score = 43.6 bits (98), Expect = 0.006
 Identities = 23/61 (37%), Positives = 36/61 (59%), Gaps = 2/61 (3%)
 Frame = -1

Query: 180 NISIIDVFATDHAPHTVEEKNSE--NPPPGYPGLETILPLLLNAVHQGRLTIEDLLCRIR 7
           N ++IDV ATDHAPH ++EK         G P ++  L  +L  V++G  TIE ++ ++ 
Sbjct: 314 NSNLIDVIATDHAPHLLKEKEGGPLKAMSGMPMIQFSLVSMLELVNEGIFTIEKVVEKMC 373

Query: 6   H 4
           H
Sbjct: 374 H 374



 Score = 35.1 bits (77), Expect = 2.2
 Identities = 25/113 (22%), Positives = 52/113 (46%), Gaps = 9/113 (7%)
 Frame = -2

Query: 557 SASCSSKDVLK*NFYNFLLEDMTIW-QKHFQSWPKKMPVCTHAEREKTAA-------VIL 402
           +A C + + +K N   ++ E +  +  +++    + +P+  HA+    AA        + 
Sbjct: 178 AAHCENHETIKKNTEKYVKEYIEKYPHQYYHVHHETLPMGYHAKIRSIAACYESSELAVR 237

Query: 401 MASLLDRPVHICHVARKEEI-LIIKAAKERGVKVTCEVCPHHLFLNSNDITKL 246
           +A + D  +HI H++   E+ L          ++T E C  HL  +S+D  +L
Sbjct: 238 LARIADARLHILHISTARELSLFDNDIPLEEKRITAEACVSHLLFDSSDYPEL 290


>UniRef50_Q1M4Y4 Cluster: Putative dihydroorotase; n=1; Rhizobium
           leguminosarum bv. viciae 3841|Rep: Putative
           dihydroorotase - Rhizobium leguminosarum bv. viciae
           (strain 3841)
          Length = 444

 Score = 48.4 bits (110), Expect = 2e-04
 Identities = 38/128 (29%), Positives = 62/128 (48%), Gaps = 7/128 (5%)
 Frame = -1

Query: 381 ACTHLSRSTKRRNINYQSRKRKRC*SYL*SLPTSLIFE***HYKIGKGRAKVCPVLCSPE 202
           A  H+ +   R  +    R R      + + P +L F     Y+    R K  P     +
Sbjct: 227 ARVHVRQINSRLGVETWRRLRSMADVTVETTPQNLFFTSD-DYESEGARLKGSPPFRGRD 285

Query: 201 DQAELWRNIS--IIDVFATDHAPHTVEEKNS-----ENPPPGYPGLETILPLLLNAVHQG 43
           D A L R +S  +I + ATDHAPH+  EK++      + P G PGL+T+L ++L+ V + 
Sbjct: 286 DVAALRRAVSEGLITIMATDHAPHSPAEKSAVYGSFADIPGGMPGLQTLLSVMLDLVAEK 345

Query: 42  RLTIEDLL 19
            + + DL+
Sbjct: 346 VIGLTDLV 353



 Score = 35.5 bits (78), Expect = 1.7
 Identities = 26/95 (27%), Positives = 41/95 (43%), Gaps = 2/95 (2%)
 Frame = -3

Query: 817 LPGFIDVHVHVREPGANIKGRF*DLLPQXHWLVVLTMICAMPNTNP--SIVDRTAFDYAS 644
           LPG +D HVH+REPG   K  F +       L  +T I  MP  +P  +   + +   AS
Sbjct: 53  LPGLVDAHVHLREPGMTQKEDF-ESGTHAAALGGVTTILDMPTDDPWTATAQQLSDKMAS 111

Query: 643 TLARVSARCDYALYVGASSTNYDTICELAPQAAAL 539
               +     +   V  S  + + +  L+P +  L
Sbjct: 112 AAGGIHVDVGFQAVVSKSYDSLEDLLALSPVSLEL 146


>UniRef50_A5ZPT0 Cluster: Dihydroorotase; n=1; Ruminococcus obeum
           ATCC 29174|Rep: Dihydroorotase - Ruminococcus obeum ATCC
           29174
          Length = 430

 Score = 48.4 bits (110), Expect = 2e-04
 Identities = 31/77 (40%), Positives = 45/77 (58%), Gaps = 5/77 (6%)
 Frame = -1

Query: 234 AKVCPVLCSPEDQAELWRNIS--IIDVFATDHAPHTVEEKNS--ENPPPGYPGLETILPL 67
           AK+ P L + +D+ E+   +    ID+ ATDHAPH+ EEK       P G  GLET L L
Sbjct: 273 AKMNPPLRTEKDRQEIIHGLKDGTIDLIATDHAPHSEEEKAKPLTEAPSGITGLETSLGL 332

Query: 66  -LLNAVHQGRLTIEDLL 19
            + + V +G L++ +LL
Sbjct: 333 GITSLVKEGYLSLMELL 349


>UniRef50_Q44184 Cluster: D-hydantoinase; n=5; Proteobacteria|Rep:
           D-hydantoinase - Agrobacterium tumefaciens
          Length = 457

 Score = 48.4 bits (110), Expect = 2e-04
 Identities = 22/70 (31%), Positives = 38/70 (54%)
 Frame = -2

Query: 431 EREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDIT 252
           E E TA  + +A +++ P++I H+  +E    +  AK RGV    E C  +L+L  +D+ 
Sbjct: 215 EAEATARALALAEIVNAPIYIVHLTCEESFDELMRAKARGVHALAETCTQYLYLTKDDLE 274

Query: 251 KLEKGEQKYV 222
           + +    KYV
Sbjct: 275 RPDFEGAKYV 284


>UniRef50_Q1Q402 Cluster: Similar to dihydroorotase; n=1; Candidatus
           Kuenenia stuttgartiensis|Rep: Similar to dihydroorotase
           - Candidatus Kuenenia stuttgartiensis
          Length = 444

 Score = 48.0 bits (109), Expect = 3e-04
 Identities = 20/40 (50%), Positives = 30/40 (75%), Gaps = 1/40 (2%)
 Frame = -2

Query: 377 VHICHVARKEEILIIKAAKERGV-KVTCEVCPHHLFLNSN 261
           +HI H++ K+ +  I+ AKERG+ K TCEV PHHL L+++
Sbjct: 246 LHISHISLKDTLAAIQQAKERGIGKFTCEVTPHHLLLDNS 285



 Score = 46.8 bits (106), Expect = 7e-04
 Identities = 25/55 (45%), Positives = 36/55 (65%), Gaps = 1/55 (1%)
 Frame = -1

Query: 171 IIDVFATDHAPHTVEEKNSENPPPGYPGLETILPLLL-NAVHQGRLTIEDLLCRI 10
           IIDV ATDHAPHT  + + +    G+ GLET L +LL   VH G +T ++L+ ++
Sbjct: 317 IIDVIATDHAPHT--DDDLKKGATGFVGLETALGVLLTKLVHTGIITFKELIIKM 369



 Score = 33.5 bits (73), Expect = 6.8
 Identities = 20/48 (41%), Positives = 23/48 (47%)
 Frame = -3

Query: 817 LPGFIDVHVHVREPGANIKGRF*DLLPQXHWLVVLTMICAMPNTNPSI 674
           +PG I+ HVH REPG   K                T+IC  PNTNP I
Sbjct: 73  IPGLIECHVHFREPGLEYKEDIRTGSRAAAKGGYTTVICE-PNTNPPI 119


>UniRef50_P77671 Cluster: Allantoinase; n=25; Bacteria|Rep:
           Allantoinase - Escherichia coli (strain K12)
          Length = 453

 Score = 47.6 bits (108), Expect = 4e-04
 Identities = 22/68 (32%), Positives = 38/68 (55%)
 Frame = -2

Query: 449 PVCTHAEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFL 270
           PV T  E E    V+ +A +    +H+CHV+  E +  +  A++ G  VTCE CPH+  L
Sbjct: 216 PVFT--EVEAIRRVLYLAKVAGCRLHVCHVSSPEGVEEVTRARQEGQDVTCESCPHYFVL 273

Query: 269 NSNDITKL 246
           +++   ++
Sbjct: 274 DTDQFEEI 281



 Score = 35.9 bits (79), Expect = 1.3
 Identities = 26/89 (29%), Positives = 37/89 (41%)
 Frame = -3

Query: 826 IVKLPGFIDVHVHVREPGANIKGRF*DLLPQXHWLVVLTMICAMPNTNPSIVDRTAFDYA 647
           +V  PG +D H H+ EPG +    +           + TMI    N  P+ VDR + +  
Sbjct: 49  LVVSPGMVDAHTHISEPGRSHWEGYETGTRAAAKGGITTMIEMPLNQLPATVDRASIELK 108

Query: 646 STLARVSARCDYALYVGASSTNYDTICEL 560
              A+     D A   G  S N D + EL
Sbjct: 109 FDAAKGKLTIDAAQLGGLVSYNIDRLHEL 137


>UniRef50_A5NXH5 Cluster: Allantoinase; n=2; Proteobacteria|Rep:
           Allantoinase - Methylobacterium sp. 4-46
          Length = 495

 Score = 47.2 bits (107), Expect = 5e-04
 Identities = 20/55 (36%), Positives = 38/55 (69%), Gaps = 5/55 (9%)
 Frame = -1

Query: 171 IIDVFATDHAPHTVEE-----KNSENPPPGYPGLETILPLLLNAVHQGRLTIEDL 22
           + D+   +HAPH+VE+     +++ + P G  G +  +PL+LNAV++GR+T++D+
Sbjct: 314 VADMLVGEHAPHSVEDVEPGWEDNFSVPLGITGAQEFVPLMLNAVNEGRMTLQDI 368


>UniRef50_A0L3T8 Cluster: Dihydroorotase, multifunctional complex
           type; n=2; unclassified Proteobacteria|Rep:
           Dihydroorotase, multifunctional complex type -
           Magnetococcus sp. (strain MC-1)
          Length = 428

 Score = 46.8 bits (106), Expect = 7e-04
 Identities = 19/64 (29%), Positives = 32/64 (50%)
 Frame = -2

Query: 446 VCTHAEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLN 267
           +C  AE       I +  L     H+ H++    +  +  A+E+G++V+CE  PHHL LN
Sbjct: 209 ICNAAEDILVERDIRLVELTGGRYHVAHISSAGAVASVAKAREKGLRVSCEAAPHHLVLN 268

Query: 266 SNDI 255
              +
Sbjct: 269 DTHV 272



 Score = 43.2 bits (97), Expect = 0.008
 Identities = 28/79 (35%), Positives = 38/79 (48%), Gaps = 4/79 (5%)
 Frame = -1

Query: 234 AKVCPVLCSPEDQAELWRNIS--IIDVFATDHAPHTVEEKNSE--NPPPGYPGLETILPL 67
           AK+ P L +  D   +   ++  +I V ATDHAPH  + K         G  GLET+LP+
Sbjct: 279 AKMAPPLRNQRDVNAIQEALARGVISVIATDHAPHEEDSKRVPFCQAANGVVGLETLLPI 338

Query: 66  LLNAVHQGRLTIEDLLCRI 10
            L  V  G L +   L  I
Sbjct: 339 TLELVEAGVLPLAKALAAI 357



 Score = 39.1 bits (87), Expect = 0.14
 Identities = 23/67 (34%), Positives = 33/67 (49%)
 Frame = -3

Query: 826 IVKLPGFIDVHVHVREPGANIKGRF*DLLPQXHWLVVLTMICAMPNTNPSIVDRTAFDYA 647
           ++  PG +D+HVH+REPG   K        +      +T + AMPNT P   D +   Y 
Sbjct: 54  LIAAPGLVDMHVHLREPGYEYKETIAG-GTRAAAAGGVTSVAAMPNTKPVNDDPSVTGYM 112

Query: 646 STLARVS 626
              ARV+
Sbjct: 113 LDKARVA 119


>UniRef50_P81006 Cluster: Non-ATP-dependent L-selective
           hydantoinase; n=3; Arthrobacter|Rep: Non-ATP-dependent
           L-selective hydantoinase - Arthrobacter aurescens
          Length = 458

 Score = 46.8 bits (106), Expect = 7e-04
 Identities = 30/79 (37%), Positives = 42/79 (53%), Gaps = 8/79 (10%)
 Frame = -1

Query: 231 KVCPVLCSPEDQAELWRNIS--IIDVFATDHAPHTVEEKNSE-----NPPPGYPGLETIL 73
           KV P + S E    LW  +   +ID   +DH  H VE+K            G  GLET L
Sbjct: 283 KVAPPVRSAEMNIRLWEQLENGLIDTLGSDHGGHPVEDKEPGWKDVWKAGNGALGLETSL 342

Query: 72  PLLL-NAVHQGRLTIEDLL 19
           P++L N V++GRL++E L+
Sbjct: 343 PMMLTNGVNKGRLSLERLV 361



 Score = 34.3 bits (75), Expect = 3.9
 Identities = 27/84 (32%), Positives = 37/84 (44%), Gaps = 1/84 (1%)
 Frame = -3

Query: 817 LPGFIDVHVHVREPG-ANIKGRF*DLLPQXHWLVVLTMICAMPNTNPSIVDRTAFDYAST 641
           +PG +D HVH+ +    N  GRF +L  +   +  +T I  MP T P      AF     
Sbjct: 53  MPGVVDEHVHIIDMDLKNRYGRF-ELDSESAAVGGITTIIEMPITFPPTTTLDAFLEKKK 111

Query: 640 LARVSARCDYALYVGASSTNYDTI 569
            A    + D+ALY G    N   I
Sbjct: 112 QAGQRLKVDFALYGGGVPGNLPEI 135


>UniRef50_O69809 Cluster: D-hydantoinase; n=4; Bacteria|Rep:
           D-hydantoinase - Streptomyces coelicolor
          Length = 467

 Score = 46.8 bits (106), Expect = 7e-04
 Identities = 21/70 (30%), Positives = 40/70 (57%)
 Frame = -2

Query: 431 EREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDIT 252
           E E T   I +A +   P+++ HV+  E +  +  A++ G+ V  E CP +LFL+++++ 
Sbjct: 223 EAEATHRAIRLAQVAGAPLYVVHVSATEAVAELTRARDEGLPVFGETCPQYLFLSTDNLA 282

Query: 251 KLEKGEQKYV 222
           + +    KYV
Sbjct: 283 EPDFEGAKYV 292



 Score = 35.1 bits (77), Expect = 2.2
 Identities = 26/78 (33%), Positives = 34/78 (43%), Gaps = 9/78 (11%)
 Frame = -1

Query: 243 KGRAKVCPVLCSP-EDQAELWRNISIID--VFATDHAPHTVEEKNS------ENPPPGYP 91
           +G   VC     P E QA LWR +   D  V +TDH P     +           P G P
Sbjct: 287 EGAKYVCSTPLRPKEHQAALWRGLRTNDLQVVSTDHCPFCFSGQKELGRGDFSRIPNGMP 346

Query: 90  GLETILPLLLNAVHQGRL 37
           G+E  + LL  AV +G +
Sbjct: 347 GVENRMDLLHQAVVEGHI 364


>UniRef50_O32137 Cluster: Allantoinase; n=1; Bacillus subtilis|Rep:
           Allantoinase - Bacillus subtilis
          Length = 446

 Score = 46.8 bits (106), Expect = 7e-04
 Identities = 19/60 (31%), Positives = 34/60 (56%)
 Frame = -2

Query: 434 AEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 255
           AE E     I  A +   PVH  H++  + + +I+ AK+ G+ V+ E CPH++  + +D+
Sbjct: 216 AEVEAVYRTIQYAKVTGCPVHFVHISTAKAVRLIREAKQEGLDVSVETCPHYVLFSHDDL 275


>UniRef50_Q831D1 Cluster: D-hydantoinase; n=6; Firmicutes|Rep:
           D-hydantoinase - Enterococcus faecalis (Streptococcus
           faecalis)
          Length = 457

 Score = 46.4 bits (105), Expect = 9e-04
 Identities = 19/57 (33%), Positives = 34/57 (59%)
 Frame = -2

Query: 431 EREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSN 261
           E E  A  +++A + D PV+I H++ K  +  ++ A++RG  V  E CP +L L+ +
Sbjct: 217 EAEAVARYLMIAEMADLPVNIVHLSTKRSLEAVERARQRGQSVYVETCPQYLLLDDH 273


>UniRef50_A4M847 Cluster: Dihydropyrimidinase; n=1; Petrotoga
           mobilis SJ95|Rep: Dihydropyrimidinase - Petrotoga
           mobilis SJ95
          Length = 451

 Score = 46.4 bits (105), Expect = 9e-04
 Identities = 29/75 (38%), Positives = 41/75 (54%), Gaps = 7/75 (9%)
 Frame = -1

Query: 222 PVLCSPEDQAELWRNIS--IIDVFATDHAPHTVEE----KNSENPPPGYPGLETILPLLL 61
           P L   +D   LW  I   +IDV ATDH  +  E+    KNS +  PG PG+ET+L L  
Sbjct: 286 PPLRESQDNEALWEGIQKGLIDVIATDHCAYNAEQKSMGKNSLDIFPGIPGVETLLALTY 345

Query: 60  N-AVHQGRLTIEDLL 19
              V++G ++I  L+
Sbjct: 346 TYGVNKGLISINRLV 360


>UniRef50_Q6A916 Cluster: Dihydroorotase; n=1; Propionibacterium
           acnes|Rep: Dihydroorotase - Propionibacterium acnes
          Length = 445

 Score = 46.0 bits (104), Expect = 0.001
 Identities = 20/65 (30%), Positives = 33/65 (50%)
 Frame = -2

Query: 449 PVCTHAEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFL 270
           P+    E  + A  +++A       H+CH + ++ I  ++  +E G  VT E  PHHL L
Sbjct: 208 PMTRLTETVQVARDVMIAEETGAHYHLCHASTRQSIRTLRRGREDGANVTGEAAPHHLLL 267

Query: 269 NSNDI 255
             +DI
Sbjct: 268 ADDDI 272



 Score = 38.7 bits (86), Expect = 0.18
 Identities = 22/54 (40%), Positives = 27/54 (50%), Gaps = 3/54 (5%)
 Frame = -3

Query: 832 GNIVKLPGFIDVHVHVREPGANIKGRF*D---LLPQXHWLVVLTMICAMPNTNP 680
           G  +  PG +D+HVH+REPG   K           +  W    T ICAMPNT P
Sbjct: 52  GGALVTPGMVDLHVHLREPGQEHKETIASGTAAAARGGW----TTICAMPNTVP 101


>UniRef50_Q3ZYB9 Cluster: Dihydroorotase, multifunctional complex
           type; n=4; Bacteria|Rep: Dihydroorotase, multifunctional
           complex type - Dehalococcoides sp. (strain CBDB1)
          Length = 428

 Score = 46.0 bits (104), Expect = 0.001
 Identities = 31/76 (40%), Positives = 39/76 (51%), Gaps = 4/76 (5%)
 Frame = -1

Query: 234 AKVCPVLCSPEDQAELWRNIS--IIDVFATDHAPHTVEEKNSE--NPPPGYPGLETILPL 67
           AKV P L +  D   L   +    ID  ATDHAPHT  +K  E      G  GLET L  
Sbjct: 276 AKVNPPLRTQTDIEALIAGLKDGTIDAIATDHAPHTRNDKLCEFGLAANGISGLETALAS 335

Query: 66  LLNAVHQGRLTIEDLL 19
           L+  VH G+L++  L+
Sbjct: 336 LMGLVHSGKLSLSLLI 351



 Score = 43.2 bits (97), Expect = 0.008
 Identities = 14/41 (34%), Positives = 27/41 (65%)
 Frame = -2

Query: 377 VHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 255
           +H+CH++    + +++ AK  G++V+ EV PHHL L   ++
Sbjct: 229 LHLCHISTAGSVELVRQAKAAGIRVSAEVTPHHLTLTEAEV 269



 Score = 42.7 bits (96), Expect = 0.011
 Identities = 27/67 (40%), Positives = 35/67 (52%), Gaps = 1/67 (1%)
 Frame = -3

Query: 823 VKLPGFIDVHVHVREPGANIKGRF*DLLPQXHWLVVLTMICAMPNTNPSIVDRTAFDY-A 647
           V  PGFID+HVH+REPG   K    +   +       T IC MPNTNP+       D+  
Sbjct: 52  VVCPGFIDLHVHLREPGFEGKETI-ESGCKAAAAGGFTSICPMPNTNPAADCLPVIDFIK 110

Query: 646 STLARVS 626
           +T  +VS
Sbjct: 111 NTATKVS 117


>UniRef50_A7HCE8 Cluster: Dihydroorotase, multifunctional complex
           type; n=10; Deltaproteobacteria|Rep: Dihydroorotase,
           multifunctional complex type - Anaeromyxobacter sp.
           Fw109-5
          Length = 433

 Score = 46.0 bits (104), Expect = 0.001
 Identities = 21/51 (41%), Positives = 29/51 (56%)
 Frame = -2

Query: 407 ILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 255
           I +  L    +H+ HV+ K  +  I+ AK RG+ VT EV PHHL L   D+
Sbjct: 221 IALVELTGGRLHVAHVSTKGAVRAIRDAKARGLPVTGEVTPHHLALTDEDV 271



 Score = 43.2 bits (97), Expect = 0.008
 Identities = 32/77 (41%), Positives = 39/77 (50%), Gaps = 1/77 (1%)
 Frame = -3

Query: 814 PGFIDVHVHVREPGANIKGRF*DLLPQXHWLVVLTMICAMPNTNPSIVDRTAFDYASTLA 635
           PGFID+HVH+REPG   K        +       T +CAMPNT P  V+  A      LA
Sbjct: 57  PGFIDLHVHLREPGQEYKETI-ATGARAAVAGGFTAVCAMPNTKP--VNDNASVTELVLA 113

Query: 634 RVSARCDYALY-VGASS 587
           R +A     +Y VGA S
Sbjct: 114 RAAAAGLARVYPVGAIS 130



 Score = 42.3 bits (95), Expect = 0.015
 Identities = 27/70 (38%), Positives = 36/70 (51%), Gaps = 4/70 (5%)
 Frame = -1

Query: 231 KVCPVLCSPEDQAELWRNIS--IIDVFATDHAPHTVEEKNSE--NPPPGYPGLETILPLL 64
           K+ P L S ED       ++   +D  ATDHAPH+  EK+ E      G  GLET  P+ 
Sbjct: 281 KMNPPLRSAEDVRACREGLADGTLDAIATDHAPHSAVEKDVEFDAAANGITGLETAFPVC 340

Query: 63  LNAVHQGRLT 34
           L+ V  G L+
Sbjct: 341 LDLVRAGALS 350


>UniRef50_A4AEE1 Cluster: Dihydroorotase and related cyclic
           amidohydrolase; n=1; marine actinobacterium
           PHSC20C1|Rep: Dihydroorotase and related cyclic
           amidohydrolase - marine actinobacterium PHSC20C1
          Length = 470

 Score = 46.0 bits (104), Expect = 0.001
 Identities = 27/68 (39%), Positives = 42/68 (61%), Gaps = 8/68 (11%)
 Frame = -1

Query: 207 PED-QAELWRNI--SIIDVFATDHAPHTVEEKN---SE--NPPPGYPGLETILPLLLNAV 52
           P+D +A +W  +    ID+ ++DHAPHT EEK    +E      G PG++    L+L+AV
Sbjct: 296 PDDNRAAIWEGMRDGTIDIASSDHAPHTREEKEIGWTEMWKAHTGTPGIQYYYELMLDAV 355

Query: 51  HQGRLTIE 28
           ++G LT+E
Sbjct: 356 NRGELTLE 363



 Score = 40.7 bits (91), Expect = 0.045
 Identities = 22/56 (39%), Positives = 31/56 (55%), Gaps = 1/56 (1%)
 Frame = -2

Query: 410 VILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNS-NDITKL 246
           V+ +A     PVHI H+  +  I  ++ AK  GV VTCEV     FL++ ND+  L
Sbjct: 231 VLRLAEASGCPVHIAHIQTRRSIEAVRRAKANGVDVTCEVNHWAPFLSTWNDVQTL 286



 Score = 40.3 bits (90), Expect = 0.059
 Identities = 25/57 (43%), Positives = 29/57 (50%), Gaps = 2/57 (3%)
 Frame = -3

Query: 832 GNIVKLPGFIDVHVHVREPGANIKGRF*DLLPQXHWLVV--LTMICAMPNTNPSIVD 668
           G +V LPG +DVHVH REPG   K    D+L          +T I  MPN  P  VD
Sbjct: 50  GRLV-LPGMVDVHVHTREPGYEHKD---DILTTTRQAAAGGVTTIFGMPNLKPPTVD 102


>UniRef50_A2R282 Cluster: Contig An13c0120, complete genome; n=3;
           Trichocomaceae|Rep: Contig An13c0120, complete genome -
           Aspergillus niger
          Length = 502

 Score = 46.0 bits (104), Expect = 0.001
 Identities = 23/57 (40%), Positives = 33/57 (57%)
 Frame = -2

Query: 434 AEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNS 264
           AE E T  VI ++ L D P+ I H++ K     ++AA+ R + V  E CPH+LF  S
Sbjct: 225 AEDEATYRVISLSELADVPILIVHMSSKLAAAHVRAAQTRLLPVHAETCPHYLFFTS 281


>UniRef50_A3DKS9 Cluster: Amidohydrolase; n=1; Staphylothermus
           marinus F1|Rep: Amidohydrolase - Staphylothermus marinus
           (strain ATCC 43588 / DSM 3639 / F1)
          Length = 447

 Score = 46.0 bits (104), Expect = 0.001
 Identities = 18/46 (39%), Positives = 26/46 (56%)
 Frame = -2

Query: 386 DRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDITK 249
           + P+HI HV+  E I  IK  + +G ++T E CPH L+    D  K
Sbjct: 222 EAPLHIAHVSSSEGIEAIKFLRRKGTRITAETCPHFLYFTREDSKK 267


>UniRef50_Q2JER9 Cluster: Allantoinase; n=5; Bacteria|Rep:
           Allantoinase - Frankia sp. (strain CcI3)
          Length = 453

 Score = 45.6 bits (103), Expect = 0.002
 Identities = 21/73 (28%), Positives = 39/73 (53%)
 Frame = -2

Query: 473 FQSWPKKMPVCTHAEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCE 294
           F SW    P    AE E  AA+  +++     +H+ H+A  + +  + AA++ G+ +T E
Sbjct: 214 FASWLASRPPA--AETEAVAALAALSAASGARLHVLHLAAADALDDVLAARDAGLPMTVE 271

Query: 293 VCPHHLFLNSNDI 255
            CPH+L   + ++
Sbjct: 272 TCPHYLTFTAEEV 284


>UniRef50_A6LUT2 Cluster: Dihydropyrimidinase; n=3; cellular
           organisms|Rep: Dihydropyrimidinase - Clostridium
           beijerinckii NCIMB 8052
          Length = 455

 Score = 45.6 bits (103), Expect = 0.002
 Identities = 30/82 (36%), Positives = 41/82 (50%), Gaps = 8/82 (9%)
 Frame = -1

Query: 255 YKIGKGRAKVC-PVLCSPEDQAELWRNISI--IDVFATDHAPHTVEEK-----NSENPPP 100
           YK   GR  VC P +   E Q  LW+ I    ID  ATDH P    EK     +    P 
Sbjct: 276 YKREDGRNFVCSPPMKGQESQDALWKAIKSGDIDTVATDHCPFQSYEKDWGKDDFTKIPN 335

Query: 99  GYPGLETILPLLLNAVHQGRLT 34
           G  G+E + P +L+A ++G++T
Sbjct: 336 GCAGVENLYPYMLSAANEGKIT 357



 Score = 42.3 bits (95), Expect = 0.015
 Identities = 31/100 (31%), Positives = 48/100 (48%)
 Frame = -2

Query: 536 DVLK*NFYNFLLEDMTIWQKHFQSWPKKMPVCTHAEREKTAAVILMASLLDRPVHICHVA 357
           D++  N  NFL E  T    H+ S P+ +     AE +K A  + +A  +  P+++ H+A
Sbjct: 189 DLIDLNIENFLKEGKTSAWYHYLSRPEFV----EAEADKRA--VHLAKSIGAPLYLVHMA 242

Query: 356 RKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDITKLEKG 237
            KE +     AK  G  +  E CP +L     D+ K E G
Sbjct: 243 DKEGLETAIEAKREGHDIYVETCPQYLEFTC-DVYKREDG 281


>UniRef50_Q9RKU5 Cluster: Probable allantoinase; n=8;
           Actinomycetales|Rep: Probable allantoinase -
           Streptomyces coelicolor
          Length = 445

 Score = 45.6 bits (103), Expect = 0.002
 Identities = 19/60 (31%), Positives = 34/60 (56%)
 Frame = -2

Query: 434 AEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 255
           AE    A ++  A   +  VH+ H++  + + +I  A+  GV+VT E CPH+L L + ++
Sbjct: 215 AEDTAIATLLAQAKRFNARVHVLHLSSSDALPLIAEARADGVRVTVETCPHYLTLTAEEV 274


>UniRef50_UPI0001597BA8 Cluster: PucH; n=1; Bacillus
           amyloliquefaciens FZB42|Rep: PucH - Bacillus
           amyloliquefaciens FZB42
          Length = 454

 Score = 45.2 bits (102), Expect = 0.002
 Identities = 22/62 (35%), Positives = 31/62 (50%)
 Frame = -2

Query: 434 AEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 255
           AE E     I  A      +H  H++ K  +L I+ AK+ G+ VT E CPH+L  +  D 
Sbjct: 216 AECEAVQRAIEYARATGCALHFVHISTKRAVLSIQQAKKDGLDVTVETCPHYLLFSFEDF 275

Query: 254 TK 249
            K
Sbjct: 276 LK 277


>UniRef50_Q67Q00 Cluster: Dihydroorotase; n=6; Bacteria|Rep:
           Dihydroorotase - Symbiobacterium thermophilum
          Length = 434

 Score = 45.2 bits (102), Expect = 0.002
 Identities = 30/76 (39%), Positives = 42/76 (55%), Gaps = 5/76 (6%)
 Frame = -1

Query: 231 KVCPVLCSPEDQAELWRNIS--IIDVFATDHAPHTVEEKNSENPPP--GYPGLETILPLL 64
           K+ P L    D+  +   ++   IDV ATDHAPH V+EK+ E P    G  GLET + L 
Sbjct: 280 KMNPPLREEADRQAILEGLADGTIDVIATDHAPHHVDEKDVEYPLAAFGITGLETAVGLA 339

Query: 63  LN-AVHQGRLTIEDLL 19
           L+  V  G + +E L+
Sbjct: 340 LDRLVRPGLIRLEQLI 355



 Score = 39.9 bits (89), Expect = 0.078
 Identities = 18/63 (28%), Positives = 31/63 (49%)
 Frame = -2

Query: 434 AEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 255
           AE    A  IL+A      VH+ H++ +  + +++  K +G +VT E  PHH  L    +
Sbjct: 211 AEEVHVARDILLALETGARVHLQHLSSRRSVELVRWGKAQGARVTAEATPHHFTLTDQAV 270

Query: 254 TKL 246
             +
Sbjct: 271 ADM 273



 Score = 34.7 bits (76), Expect = 2.9
 Identities = 21/50 (42%), Positives = 25/50 (50%)
 Frame = -3

Query: 823 VKLPGFIDVHVHVREPGANIKGRF*DLLPQXHWLVVLTMICAMPNTNPSI 674
           V  PGFIDVHVH+R PG   K               + ++C MPNT P I
Sbjct: 53  VVAPGFIDVHVHLRVPGQEYKEDMRTGTAAAVRGGFVGVVC-MPNTRPVI 101


>UniRef50_A3ESI6 Cluster: Dihydroorotase; n=3; Bacteria|Rep:
           Dihydroorotase - Leptospirillum sp. Group II UBA
          Length = 438

 Score = 45.2 bits (102), Expect = 0.002
 Identities = 31/76 (40%), Positives = 39/76 (51%), Gaps = 4/76 (5%)
 Frame = -1

Query: 234 AKVCPVLCSPEDQAELWRNI--SIIDVFATDHAPHTVEEKNSE--NPPPGYPGLETILPL 67
           AK+ P L + ED+  +   +    ID+ ATDHAPH   EK  E    P G  GLET   L
Sbjct: 283 AKMNPPLRTEEDRLAIIEGLRDGTIDMIATDHAPHAPFEKEREFDQAPFGIIGLETAFSL 342

Query: 66  LLNAVHQGRLTIEDLL 19
            L  V+ G L +  LL
Sbjct: 343 GLQLVNSGVLDLSMLL 358



 Score = 35.9 bits (79), Expect = 1.3
 Identities = 12/41 (29%), Positives = 24/41 (58%)
 Frame = -2

Query: 377 VHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 255
           +H+ H++    + +++ AK+R + VT E CPH+  L    +
Sbjct: 236 LHVAHLSTAGGVRLVREAKKRHLHVTAETCPHYFSLTDEAV 276



 Score = 33.5 bits (73), Expect = 6.8
 Identities = 17/45 (37%), Positives = 22/45 (48%)
 Frame = -3

Query: 814 PGFIDVHVHVREPGANIKGRF*DLLPQXHWLVVLTMICAMPNTNP 680
           PG +DVH H REPG   K    +   +       T +C M NT+P
Sbjct: 62  PGLVDVHAHFREPGFEYKETI-ESGSRAAVSGGFTAVCVMANTDP 105


>UniRef50_A1SH63 Cluster: Dihydropyrimidinase; n=1; Nocardioides sp.
           JS614|Rep: Dihydropyrimidinase - Nocardioides sp.
           (strain BAA-499 / JS614)
          Length = 467

 Score = 45.2 bits (102), Expect = 0.002
 Identities = 28/97 (28%), Positives = 49/97 (50%)
 Frame = -2

Query: 512 NFLLEDMTIWQKHFQSWPKKMPVCTHAEREKTAAVILMASLLDRPVHICHVARKEEILII 333
           + ++E +   +K   + P   P    AE  + AAV+  A+  D  +++ H++    +  +
Sbjct: 198 SLVVEALAAGRKGPDAIPAVRPDSVEAEAIRRAAVLAAAA--DTSLYVVHLSSAAGLEAV 255

Query: 332 KAAKERGVKVTCEVCPHHLFLNSNDITKLEKGEQKYV 222
           +AA+  G  V  E CPH+L+L   D   LE GE  +V
Sbjct: 256 RAARAVGADVHAETCPHYLYL---DQAHLEAGEPDFV 289



 Score = 36.7 bits (81), Expect = 0.72
 Identities = 28/88 (31%), Positives = 38/88 (43%), Gaps = 12/88 (13%)
 Frame = -1

Query: 258 HYKIGKGRAKVCPVLCSPEDQAELWRNISI--IDVFATDHAPHTVEEKNS---------- 115
           H + G+      P L    D+A LW  I+   ++V ATDH P T  ++            
Sbjct: 280 HLEAGEPDFVCAPPLRGAADRAALWGAIAAGEVEVVATDHCPFTRADRRRGTGGDGWADF 339

Query: 114 ENPPPGYPGLETILPLLLNAVHQGRLTI 31
              P G  G+ET L L    V  GRLT+
Sbjct: 340 RQLPGGLSGVETRLALAYQGVVSGRLTL 367


>UniRef50_UPI00015BD532 Cluster: UPI00015BD532 related cluster; n=1;
           unknown|Rep: UPI00015BD532 UniRef100 entry - unknown
          Length = 424

 Score = 44.8 bits (101), Expect = 0.003
 Identities = 22/71 (30%), Positives = 35/71 (49%)
 Frame = -3

Query: 826 IVKLPGFIDVHVHVREPGANIKGRF*DLLPQXHWLVVLTMICAMPNTNPSIVDRTAFDYA 647
           ++   GF+D+H H+R+PG   K      +    +    T++C MPNTNP I + +   Y 
Sbjct: 52  LIACSGFVDIHAHLRDPGFTYKEDLESGMKAATFGGFTTIVC-MPNTNPPIDNESIISYI 110

Query: 646 STLARVSARCD 614
            + A     CD
Sbjct: 111 LSKAEKIGICD 121



 Score = 43.6 bits (98), Expect = 0.006
 Identities = 21/59 (35%), Positives = 34/59 (57%)
 Frame = -2

Query: 440 THAEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNS 264
           ++AE    A   +++      +HI H++    + I+K  KE+G  +TCEV P+HL LNS
Sbjct: 209 SYAEDVMVARDCILSYKTGGKLHIQHLSSSLSVDIVKFFKEKGANITCEVNPNHLALNS 267



 Score = 39.5 bits (88), Expect = 0.10
 Identities = 19/52 (36%), Positives = 29/52 (55%), Gaps = 1/52 (1%)
 Frame = -1

Query: 171 IIDVFATDHAPHTVEEK-NSENPPPGYPGLETILPLLLNAVHQGRLTIEDLL 19
           +ID  ATDHAPH   EK +      G  G +  LP++++ V  G + I+ L+
Sbjct: 300 VIDCIATDHAPHAKNEKLHPIKGAAGMLGFQVALPIIMSLVKDGVIDIKSLI 351


>UniRef50_Q89Q35 Cluster: D-hydantoinase; n=20; Proteobacteria|Rep:
           D-hydantoinase - Bradyrhizobium japonicum
          Length = 486

 Score = 44.8 bits (101), Expect = 0.003
 Identities = 21/62 (33%), Positives = 37/62 (59%)
 Frame = -2

Query: 431 EREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDIT 252
           ERE T   I  A ++  P+ I HV+ +E +  ++ A++RG+ V  E CP ++ L ++D+ 
Sbjct: 236 EREATHRAISHAEIVGVPIMIVHVSGREAMEQVRWAQQRGLPVHAETCPQYITLTADDMK 295

Query: 251 KL 246
            L
Sbjct: 296 GL 297



 Score = 35.9 bits (79), Expect = 1.3
 Identities = 25/81 (30%), Positives = 41/81 (50%), Gaps = 18/81 (22%)
 Frame = -1

Query: 216 LCSP-----EDQAELWRNIS--IIDVFATDHAPHTVEE-KNSENP---------PPGYPG 88
           +CSP     E Q  +W  I+  +   F++DH P   ++ K    P         P G PG
Sbjct: 307 VCSPPPRDAESQQAIWEGITSGVFQTFSSDHCPFRYDDPKGKLTPNSRTSFRWVPNGIPG 366

Query: 87  LETILPLLLN-AVHQGRLTIE 28
           +ET LP+L +  V +GR++++
Sbjct: 367 VETRLPILFSEGVSKGRISLQ 387


>UniRef50_A6E6Y3 Cluster: Dihydroorotase; n=1; Pedobacter sp.
           BAL39|Rep: Dihydroorotase - Pedobacter sp. BAL39
          Length = 420

 Score = 44.8 bits (101), Expect = 0.003
 Identities = 19/53 (35%), Positives = 32/53 (60%)
 Frame = -2

Query: 434 AEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHL 276
           AE    +  I +A+  D P+HI ++     + +IK AK+ G+K++C+V  HHL
Sbjct: 210 AEEMHISRDIFLAAYHDAPLHISNITTAGAVSLIKKAKKDGLKISCDVAAHHL 262


>UniRef50_Q5KFL1 Cluster: Dihydropyrimidinase, putative; n=2;
           Filobasidiella neoformans|Rep: Dihydropyrimidinase,
           putative - Cryptococcus neoformans (Filobasidiella
           neoformans)
          Length = 471

 Score = 44.8 bits (101), Expect = 0.003
 Identities = 21/61 (34%), Positives = 31/61 (50%)
 Frame = -2

Query: 431 EREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDIT 252
           E E T+  I++A ++  PV   HV       +I+ A+ RG  V  E CP +L L   D+ 
Sbjct: 245 EMEATSRAIVLAEMIQNPVLFVHVGSASAAEVIRNAQTRGFPVFAETCPQYLHLTWEDLK 304

Query: 251 K 249
           K
Sbjct: 305 K 305


>UniRef50_UPI000038E4AB Cluster: hypothetical protein Faci_03000487;
           n=1; Ferroplasma acidarmanus fer1|Rep: hypothetical
           protein Faci_03000487 - Ferroplasma acidarmanus fer1
          Length = 457

 Score = 44.4 bits (100), Expect = 0.004
 Identities = 30/79 (37%), Positives = 39/79 (49%), Gaps = 8/79 (10%)
 Frame = -1

Query: 240 GRAKVC-PVLCSPEDQAELWRNISI--IDVFATDHAPHTVEEKNSENP----PPGYPGLE 82
           G   +C P L   ED   +W  IS   I    +DH P    +K    P    P G PG+E
Sbjct: 283 GNLYLCSPPLRKKEDINAMWNAISSGKIQAVGSDHVPFLAYQKKKGIPFNKVPNGIPGIE 342

Query: 81  TILPLLLN-AVHQGRLTIE 28
           T LPLL +  V +GR+T+E
Sbjct: 343 TRLPLLFSEGVQKGRITLE 361


>UniRef50_Q89K18 Cluster: Blr5100 protein; n=43;
           Alphaproteobacteria|Rep: Blr5100 protein -
           Bradyrhizobium japonicum
          Length = 436

 Score = 44.4 bits (100), Expect = 0.004
 Identities = 27/75 (36%), Positives = 40/75 (53%), Gaps = 4/75 (5%)
 Frame = -1

Query: 231 KVCPVLCSPEDQAELWRNIS--IIDVFATDHAPHTVEEKNSE--NPPPGYPGLETILPLL 64
           K+ P L + +D+  L   ++  +IDV  +DH P  VE K        PG  GLET+LP  
Sbjct: 288 KLSPPLRTEDDRRALVAAVASGLIDVIMSDHNPQDVEVKRLPFAEAAPGAVGLETMLPAG 347

Query: 63  LNAVHQGRLTIEDLL 19
           L  +H G L ++ L+
Sbjct: 348 LRLMHNGELDLKTLI 362


>UniRef50_A6PU21 Cluster: Dihydroorotase, multifunctional complex
           type; n=1; Victivallis vadensis ATCC BAA-548|Rep:
           Dihydroorotase, multifunctional complex type -
           Victivallis vadensis ATCC BAA-548
          Length = 369

 Score = 44.4 bits (100), Expect = 0.004
 Identities = 21/64 (32%), Positives = 36/64 (56%)
 Frame = -2

Query: 434 AEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 255
           +E    A  I++A  +   +H+ HV+ KE + +++ A+ +G+ VT E  PHHL L    I
Sbjct: 207 SEELMIARNIILARQIGWKIHMQHVSVKESVELLRNARAKGIPVTGEATPHHLTLTDECI 266

Query: 254 TKLE 243
            K +
Sbjct: 267 KKYD 270



 Score = 40.3 bits (90), Expect = 0.059
 Identities = 25/70 (35%), Positives = 32/70 (45%)
 Frame = -3

Query: 832 GNIVKLPGFIDVHVHVREPGANIKGRF*DLLPQXHWLVVLTMICAMPNTNPSIVDRTAFD 653
           G  V  PGFID+HVH+R+PG N+                 T + AMPNTNP      A +
Sbjct: 46  GGKVLSPGFIDLHVHLRQPGNNMAETIASGTAAAA-AGGFTSVVAMPNTNPPADTAGAIE 104

Query: 652 YASTLARVSA 623
           +    A   A
Sbjct: 105 FLRQTAAKKA 114



 Score = 39.1 bits (87), Expect = 0.14
 Identities = 26/59 (44%), Positives = 32/59 (54%), Gaps = 4/59 (6%)
 Frame = -1

Query: 231 KVCPVLCSPEDQAELWRNIS--IIDVFATDHAPHTVEEKNSE--NPPPGYPGLETILPL 67
           K+ P L S ED+  L   ++   I   ATDHAPHT+  K  E    P G  GLET LP+
Sbjct: 274 KMNPPLRSEEDRLALIAGVADGTITAIATDHAPHTMTAKMVEFDYAPFGIIGLETALPV 332


>UniRef50_Q8NQ39 Cluster: Dihydroorotase; n=35; Actinomycetales|Rep:
           Dihydroorotase - Corynebacterium glutamicum
           (Brevibacterium flavum)
          Length = 447

 Score = 44.4 bits (100), Expect = 0.004
 Identities = 20/55 (36%), Positives = 30/55 (54%)
 Frame = -2

Query: 434 AEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFL 270
           AE        +MA      VHICH + +  + +++ AK +G+ +T EV PHHL L
Sbjct: 224 AEESIVVRDAIMARDYGNRVHICHASTEGTVELLRWAKSQGIPITAEVTPHHLTL 278



 Score = 42.7 bits (96), Expect = 0.011
 Identities = 27/62 (43%), Positives = 34/62 (54%), Gaps = 4/62 (6%)
 Frame = -1

Query: 231 KVCPVLCSPEDQAELWRNI--SIIDVFATDHAPHTVEEK--NSENPPPGYPGLETILPLL 64
           KV P L    D   L + +    IDV ATDHAPH  E+K    EN  PG  GLET L ++
Sbjct: 291 KVNPPLRESRDAEALKKALLDGTIDVVATDHAPHGSEDKCCEFENAKPGMLGLETSLSII 350

Query: 63  LN 58
           ++
Sbjct: 351 VD 352



 Score = 35.9 bits (79), Expect = 1.3
 Identities = 13/17 (76%), Positives = 16/17 (94%)
 Frame = -3

Query: 823 VKLPGFIDVHVHVREPG 773
           V LPGF+D+HVH+REPG
Sbjct: 64  VLLPGFVDMHVHLREPG 80


>UniRef50_Q1IJ01 Cluster: Dihydroorotase, multifunctional complex
           type; n=1; Acidobacteria bacterium Ellin345|Rep:
           Dihydroorotase, multifunctional complex type -
           Acidobacteria bacterium (strain Ellin345)
          Length = 429

 Score = 44.0 bits (99), Expect = 0.005
 Identities = 21/43 (48%), Positives = 25/43 (58%), Gaps = 2/43 (4%)
 Frame = -1

Query: 168 IDVFATDHAPHTVEEKNSE--NPPPGYPGLETILPLLLNAVHQ 46
           +D  ATDHAPH   EK  E    P G  GLET LPL +  +H+
Sbjct: 303 LDCIATDHAPHAYHEKEQEFDRAPFGIIGLETALPLAITVLHK 345



 Score = 41.5 bits (93), Expect = 0.025
 Identities = 22/50 (44%), Positives = 29/50 (58%)
 Frame = -3

Query: 829 NIVKLPGFIDVHVHVREPGANIKGRF*DLLPQXHWLVVLTMICAMPNTNP 680
           ++V  PGFID+HVH+REPG   K        +       T +CAMPNT+P
Sbjct: 54  HLVVAPGFIDLHVHLREPGQAHKETI-ASGTRSAAAGGFTSVCAMPNTSP 102



 Score = 37.9 bits (84), Expect = 0.31
 Identities = 14/41 (34%), Positives = 25/41 (60%)
 Frame = -2

Query: 377 VHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 255
           +H+ H++  E +  ++ AK+  ++VT EV PHH  L   +I
Sbjct: 232 LHVAHISTAEALDAVRRAKKENLRVTAEVTPHHFTLLDENI 272


>UniRef50_Q18WQ5 Cluster: Dihydroorotase, multifunctional complex
           type; n=2; Desulfitobacterium hafniense|Rep:
           Dihydroorotase, multifunctional complex type -
           Desulfitobacterium hafniense (strain DCB-2)
          Length = 444

 Score = 44.0 bits (99), Expect = 0.005
 Identities = 21/60 (35%), Positives = 32/60 (53%)
 Frame = -2

Query: 434 AEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 255
           AE    A V  +A      V I H++  + + I++ AKE G KV  E+CP +L+L  N +
Sbjct: 211 AEAISVANVCFIAKETGAHVTIAHLSHPDVVGIVQEAKEAGAKVLAEICPQYLYLEENTL 270


>UniRef50_A2U746 Cluster: Dihydropyrimidinase; n=3; Bacillus|Rep:
           Dihydropyrimidinase - Bacillus coagulans 36D1
          Length = 471

 Score = 44.0 bits (99), Expect = 0.005
 Identities = 24/71 (33%), Positives = 37/71 (52%)
 Frame = -2

Query: 434 AEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 255
           AE E T   I +A + D  +++ HV   E +  I  A+ +G KV  E CP +L L+ + +
Sbjct: 216 AEGEATHRAIELAHMADSQLYVVHVTCAEAVKQIAEARAKGYKVWGETCPQYLVLDQSYL 275

Query: 254 TKLEKGEQKYV 222
            K +    KYV
Sbjct: 276 EKPDFEGAKYV 286


>UniRef50_Q9P903 Cluster: Dihydropyrimidinase; n=2;
           Saccharomycetaceae|Rep: Dihydropyrimidinase -
           Saccharomyces kluyveri (Yeast) (Saccharomyces
           silvestris)
          Length = 542

 Score = 44.0 bits (99), Expect = 0.005
 Identities = 22/61 (36%), Positives = 35/61 (57%)
 Frame = -2

Query: 431 EREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDIT 252
           E E T   I +A+ +D P+   HV+  +   +IK A+ +G+KV  E CP +  L S+ IT
Sbjct: 233 EGEATNRAITLATTMDTPILFVHVSSPQAAEVIKQAQTKGLKVYAETCPQYALL-SDAIT 291

Query: 251 K 249
           +
Sbjct: 292 R 292


>UniRef50_A3LNF2 Cluster: Allantoinase; n=2; Saccharomycetales|Rep:
           Allantoinase - Pichia stipitis (Yeast)
          Length = 579

 Score = 44.0 bits (99), Expect = 0.005
 Identities = 18/42 (42%), Positives = 28/42 (66%)
 Frame = -2

Query: 380 PVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 255
           P+HI H+A  E + +I+AAK +G+ +T E C H+L L +  I
Sbjct: 357 PLHIVHLATHEAVPLIRAAKAKGLPITAETCFHYLSLYAESI 398


>UniRef50_A1C896 Cluster: Aminohydrolase; n=6; cellular
           organisms|Rep: Aminohydrolase - Aspergillus clavatus
          Length = 493

 Score = 44.0 bits (99), Expect = 0.005
 Identities = 21/61 (34%), Positives = 31/61 (50%)
 Frame = -2

Query: 431 EREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDIT 252
           E E T   I +  L+  P+ I HV+      II+ A+  G+ V  E CP +LFL   ++ 
Sbjct: 228 ESEATNRAIALGQLIQTPILIVHVSSPSAAEIIRQAQTNGLPVYAETCPQYLFLTRAELD 287

Query: 251 K 249
           K
Sbjct: 288 K 288


>UniRef50_Q73KW0 Cluster: Dihydroorotase, putative; n=1; Treponema
           denticola|Rep: Dihydroorotase, putative - Treponema
           denticola
          Length = 371

 Score = 43.6 bits (98), Expect = 0.006
 Identities = 18/67 (26%), Positives = 32/67 (47%)
 Frame = -2

Query: 449 PVCTHAEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFL 270
           P     E  K    ++ +      +H+CH++ KE I ++  AK+ G+ ++C    HH  L
Sbjct: 163 PPIAETESIKDQIELMQSEDFKGHLHVCHISTKEGIRLVAEAKKSGLSISCGATAHHALL 222

Query: 269 NSNDITK 249
           N +   K
Sbjct: 223 NIDSYKK 229


>UniRef50_A5DY43 Cluster: Putative uncharacterized protein; n=1;
           Lodderomyces elongisporus NRRL YB-4239|Rep: Putative
           uncharacterized protein - Lodderomyces elongisporus
           (Yeast) (Saccharomyces elongisporus)
          Length = 617

 Score = 43.6 bits (98), Expect = 0.006
 Identities = 21/61 (34%), Positives = 37/61 (60%), Gaps = 1/61 (1%)
 Frame = -2

Query: 431 EREKTAAVILMASLLDR-PVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 255
           E    A +I  ++L+   P+HI H+A  E + +++AAK +G+ +T E C H+L L +  I
Sbjct: 378 ETTAIAEIINCSTLIPSVPLHIVHLATHEAVPLLRAAKAKGLPITAETCFHYLSLCAEKI 437

Query: 254 T 252
           +
Sbjct: 438 S 438


>UniRef50_Q1VPD0 Cluster: Dihydroorotase; n=11; Bacteroidetes|Rep:
           Dihydroorotase - Psychroflexus torquis ATCC 700755
          Length = 452

 Score = 43.2 bits (97), Expect = 0.008
 Identities = 25/87 (28%), Positives = 42/87 (48%), Gaps = 2/87 (2%)
 Frame = -3

Query: 814 PGFIDVHVHVREPGANIKGRF*DLLPQXHWLVV--LTMICAMPNTNPSIVDRTAFDYAST 641
           PG ID  VH R+PG   KG   DL  +    +   +T    MPNT P+I+   +      
Sbjct: 54  PGIIDGQVHFRDPGLTHKG---DLYTESKAAIAGGVTSFIDMPNTVPNILTVESLKEKFD 110

Query: 640 LARVSARCDYALYVGASSTNYDTICEL 560
           +A   +  +Y+ ++G +  N D + ++
Sbjct: 111 IASKKSLANYSFFLGVNGDNIDEVVKM 137



 Score = 39.5 bits (88), Expect = 0.10
 Identities = 20/57 (35%), Positives = 32/57 (56%), Gaps = 2/57 (3%)
 Frame = -1

Query: 168 IDVFATDHAPHTVEEKNSE--NPPPGYPGLETILPLLLNAVHQGRLTIEDLLCRIRH 4
           ID+  TDHAPHT+EEK         G P ++  L  +L    QG +++E ++ ++ H
Sbjct: 306 IDLITTDHAPHTLEEKQQPYFQSMSGAPMVQHTLNCMLEFYKQGLISLEKIVEKMCH 362


>UniRef50_Q9RV76 Cluster: Probable allantoinase; n=4; Bacteria|Rep:
           Probable allantoinase - Deinococcus radiodurans
          Length = 448

 Score = 43.2 bits (97), Expect = 0.008
 Identities = 20/68 (29%), Positives = 34/68 (50%)
 Frame = -2

Query: 449 PVCTHAEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFL 270
           PV T  E  + A  +L A      +H+ HV+    + +    K++G+ VT E CPH+L  
Sbjct: 213 PVVTELEAVQRA--LLFAQDTGAALHLVHVSSGAAVALAYEGKQKGIDVTIETCPHYLHF 270

Query: 269 NSNDITKL 246
              D+ ++
Sbjct: 271 TGEDVERV 278



 Score = 39.1 bits (87), Expect = 0.14
 Identities = 26/87 (29%), Positives = 41/87 (47%), Gaps = 1/87 (1%)
 Frame = -3

Query: 814 PGFIDVHVHVREPGANIKGRF*DLLPQXHWLVVLTMICAMP-NTNPSIVDRTAFDYASTL 638
           PG +D HVH+ EPG      F +   Q       T    MP N++P ++ R  F+  + L
Sbjct: 54  PGVLDDHVHLNEPGRTHWEGF-ETGTQALAAGGATSFLDMPLNSSPPVLTRERFEDKARL 112

Query: 637 ARVSARCDYALYVGASSTNYDTICELA 557
               +  D+ L+ G +  N D + +LA
Sbjct: 113 GEEKSLIDFGLWGGLTPLNLDQLDDLA 139


>UniRef50_Q2SMZ8 Cluster: Dihydroorotase and related cyclic
           amidoHydrolase; n=3; Gammaproteobacteria|Rep:
           Dihydroorotase and related cyclic amidoHydrolase -
           Hahella chejuensis (strain KCTC 2396)
          Length = 455

 Score = 42.7 bits (96), Expect = 0.011
 Identities = 22/49 (44%), Positives = 28/49 (57%)
 Frame = -2

Query: 416 AAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFL 270
           AA    A  +D  VHI H++  E +  I AAKE G+  T E CPH+L L
Sbjct: 223 AARDFKAQGVDCKVHIVHLSSAEALAAIGAAKESGLTFTVETCPHYLTL 271



 Score = 34.7 bits (76), Expect = 2.9
 Identities = 12/20 (60%), Positives = 15/20 (75%)
 Frame = -3

Query: 832 GNIVKLPGFIDVHVHVREPG 773
           GN V +PG +D HVH+ EPG
Sbjct: 49  GNDVVMPGLVDTHVHINEPG 68


>UniRef50_A4EA66 Cluster: Putative uncharacterized protein; n=1;
           Collinsella aerofaciens ATCC 25986|Rep: Putative
           uncharacterized protein - Collinsella aerofaciens ATCC
           25986
          Length = 455

 Score = 42.7 bits (96), Expect = 0.011
 Identities = 26/71 (36%), Positives = 41/71 (57%), Gaps = 2/71 (2%)
 Frame = -2

Query: 431 EREKTAAVILMASLL-DRPVHICHVARKEEILIIKAAKERGVK-VTCEVCPHHLFLNSND 258
           E E  + ++ +A L  D PV++ H++ K  +  I+AAK RG K +  E CP +L L  +D
Sbjct: 215 EGEAVSRLLYLAHLAGDAPVNVVHLSTKLGLEAIRAAKARGQKNIYVETCPQYLML--DD 272

Query: 257 ITKLEKGEQKY 225
              LE+GE  +
Sbjct: 273 TCYLEQGEDGF 283


>UniRef50_A4C048 Cluster: Amidohydrolase family, putative; n=10;
           Bacteroidetes|Rep: Amidohydrolase family, putative -
           Polaribacter irgensii 23-P
          Length = 441

 Score = 42.7 bits (96), Expect = 0.011
 Identities = 18/64 (28%), Positives = 38/64 (59%)
 Frame = -2

Query: 434 AEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 255
           AE  + A+ +L+       +HI  ++  + + +IK AK++G++V+C V  HHL L  +++
Sbjct: 232 AEELQIASNLLILEYTGGKLHIPTISTAKSVTLIKDAKKKGLQVSCSVAAHHLVLTDDEL 291

Query: 254 TKLE 243
            + +
Sbjct: 292 HEFD 295


>UniRef50_Q64E81 Cluster: Dihydroorotase; n=1; uncultured archaeon
           GZfos13E1|Rep: Dihydroorotase - uncultured archaeon
           GZfos13E1
          Length = 456

 Score = 42.7 bits (96), Expect = 0.011
 Identities = 30/111 (27%), Positives = 52/111 (46%), Gaps = 5/111 (4%)
 Frame = -3

Query: 835 HGNIVKLPGFIDVHVHVREPGANIKGRF*DLLPQXHWLVV---LTMICAMPNTNPSIVDR 665
           HG ++  PGFID+H H+RE  ++ K  + +         +   +T +  MPNT    ++ 
Sbjct: 52  HGCLI-FPGFIDIHAHLREDSSH-KWDYKEDFGTGSAAAIHGGITTVVDMPNTPLPGINA 109

Query: 664 TAFDYASTLARVSAR--CDYALYVGASSTNYDTICELAPQAAALKMYLNET 518
                   LAR +++   D   Y G + +N   I ++  +    K+YL ET
Sbjct: 110 DRIRKKRELARSTSKGLIDVFFYGGVTESNLSAIADMQKEVVGYKIYLCET 160



 Score = 38.7 bits (86), Expect = 0.18
 Identities = 22/63 (34%), Positives = 36/63 (57%)
 Frame = -2

Query: 377 VHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDITKLEKGEQKYVQYYVVLKT 198
           ++I HV+  E + +IK  K     V CEV PHHLF N+ D+      +Q +++    L+T
Sbjct: 254 INIAHVSVYETLSMIKQYKN----VHCEVTPHHLFFNTADVL----AKQAFLKMNPPLRT 305

Query: 197 KQN 189
           ++N
Sbjct: 306 EEN 308



 Score = 36.7 bits (81), Expect = 0.72
 Identities = 18/32 (56%), Positives = 21/32 (65%), Gaps = 2/32 (6%)
 Frame = -1

Query: 168 IDVFATDHAPHTVEEKNSE--NPPPGYPGLET 79
           ID  ATDHAPHT EEK+ +    P G P L+T
Sbjct: 321 IDFLATDHAPHTREEKSLDFSVAPAGVPNLDT 352


>UniRef50_A0RTM1 Cluster: Dihydroorotase; n=2; Thermoprotei|Rep:
           Dihydroorotase - Cenarchaeum symbiosum
          Length = 482

 Score = 42.7 bits (96), Expect = 0.011
 Identities = 27/77 (35%), Positives = 42/77 (54%), Gaps = 6/77 (7%)
 Frame = -1

Query: 234 AKVCPVLCSPEDQAELWRNISI--IDVFATDHAPHTVEEKNSEN---PPPGYPGLETILP 70
           AKV P + +  D   +W  I+   ID   TDH  + +  K  ++      G+PG  T+LP
Sbjct: 314 AKVMPPIRTSSDVDAVWAAITAGEIDTIGTDHVANRLGRKLGDDVWDSLAGFPGAGTLLP 373

Query: 69  LLLN-AVHQGRLTIEDL 22
           LLL+  V++ R+T+E L
Sbjct: 374 LLLSEGVNKNRITLEGL 390


>UniRef50_Q51551 Cluster: Dihydroorotase-like protein; n=14;
           Gammaproteobacteria|Rep: Dihydroorotase-like protein -
           Pseudomonas aeruginosa
          Length = 423

 Score = 42.7 bits (96), Expect = 0.011
 Identities = 20/58 (34%), Positives = 29/58 (50%), Gaps = 2/58 (3%)
 Frame = -1

Query: 171 IIDVFATDHAPHTVEEKNSE--NPPPGYPGLETILPLLLNAVHQGRLTIEDLLCRIRH 4
           ++   A+ H PH  + KN+      PG  G E +LPL +  V  G L +  LL R+ H
Sbjct: 299 VVQAIASHHQPHEADAKNAPFAATEPGISGAELLLPLAMTLVQDGLLDLPTLLARLSH 356


>UniRef50_Q9WYH0 Cluster: Dihydroorotase; n=4; Thermotogaceae|Rep:
           Dihydroorotase - Thermotoga maritima
          Length = 376

 Score = 42.7 bits (96), Expect = 0.011
 Identities = 25/72 (34%), Positives = 35/72 (48%), Gaps = 2/72 (2%)
 Frame = -1

Query: 231 KVCPVLCSPEDQAELWRNIS--IIDVFATDHAPHTVEEKNSENPPPGYPGLETILPLLLN 58
           K+ P L SPED+  L   +   +IDV ATDHAPH  +  +    P G   +E   P    
Sbjct: 228 KINPPLGSPEDRRALIEAVKKDVIDVLATDHAPHHEKPDDFLTAPYGSTSIEIAFPAYYT 287

Query: 57  AVHQGRLTIEDL 22
           A+    L ++ L
Sbjct: 288 ALGDLELVVKKL 299



 Score = 37.9 bits (84), Expect = 0.31
 Identities = 19/40 (47%), Positives = 22/40 (55%)
 Frame = -2

Query: 374 HICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 255
           HI HV  K  + +I   K    KV+CEV PHHLF    DI
Sbjct: 184 HIQHVTTKYSVEVISFLKNLA-KVSCEVTPHHLFFCYEDI 222


>UniRef50_Q8YRV3 Cluster: Dihydroorotase; n=8; Cyanobacteria|Rep:
           Dihydroorotase - Anabaena sp. (strain PCC 7120)
          Length = 435

 Score = 42.3 bits (95), Expect = 0.015
 Identities = 25/53 (47%), Positives = 28/53 (52%), Gaps = 3/53 (5%)
 Frame = -1

Query: 171 IIDVFATDHAPHTVEEKNS--ENPPPGYPGLETILPLL-LNAVHQGRLTIEDL 22
           +ID  A DHAP+T EEK       PPG  G E  LPLL  N V  G  T  +L
Sbjct: 317 VIDAIAIDHAPYTYEEKVQAFAEAPPGAIGFELALPLLWQNLVETGEFTALEL 369



 Score = 34.3 bits (75), Expect = 3.9
 Identities = 20/66 (30%), Positives = 35/66 (53%), Gaps = 1/66 (1%)
 Frame = -2

Query: 449 PVCTHAEREKTAAVI-LMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLF 273
           P+   AE    AA++ L+A+  +  VHI  V+    + +I AAK +G+ +T      HL 
Sbjct: 222 PIPPSAETSAIAALLELVAASGNTQVHIMRVSTARSVELIAAAKAQGLPITASTTWLHLL 281

Query: 272 LNSNDI 255
           L++  +
Sbjct: 282 LDTKAV 287


>UniRef50_Q5FRG9 Cluster: Dihydroorotase; n=4; Rhodospirillales|Rep:
           Dihydroorotase - Gluconobacter oxydans (Gluconobacter
           suboxydans)
          Length = 433

 Score = 42.3 bits (95), Expect = 0.015
 Identities = 19/64 (29%), Positives = 34/64 (53%)
 Frame = -2

Query: 446 VCTHAEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLN 267
           V   AE    A  + + ++    +H  HV+  E + +I+ AK RG++VTC+  P +  + 
Sbjct: 206 VPAEAEAIMIARDLRLTAMTGARLHFAHVSTAEGLDLIREAKSRGIRVTCDTAPPYFAMT 265

Query: 266 SNDI 255
            +DI
Sbjct: 266 EDDI 269


>UniRef50_A7B6D5 Cluster: Putative uncharacterized protein; n=1;
           Ruminococcus gnavus ATCC 29149|Rep: Putative
           uncharacterized protein - Ruminococcus gnavus ATCC 29149
          Length = 462

 Score = 42.3 bits (95), Expect = 0.015
 Identities = 29/82 (35%), Positives = 45/82 (54%), Gaps = 9/82 (10%)
 Frame = -1

Query: 237 RAKVCPVLCSPEDQAELWRNIS--IIDVFATDHAP-HTVEEKNSENP-----PPGYPGLE 82
           +A + P L   EDQ  LW+ +   +IDV ATDH P H  +EK +        P G PG+E
Sbjct: 284 KAIMSPPLRKKEDQDALWQALKDGVIDVVATDHCPFHFGKEKQAGAQDFTACPNGAPGVE 343

Query: 81  TILPLLLN-AVHQGRLTIEDLL 19
             + +L +  V +GR+T+  ++
Sbjct: 344 ERMRILFSEGVMKGRITLPQMV 365


>UniRef50_Q4AGB4 Cluster: Dihydropyrimidinase; n=1; Chlorobium
           phaeobacteroides BS1|Rep: Dihydropyrimidinase -
           Chlorobium phaeobacteroides BS1
          Length = 455

 Score = 41.5 bits (93), Expect = 0.025
 Identities = 20/67 (29%), Positives = 32/67 (47%)
 Frame = -2

Query: 461 PKKMPVCTHAEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPH 282
           P+  P   H E E     I +A     P++I H++ K  +  +K A+  G  V  E CP 
Sbjct: 210 PQSRPA--HLETEAVEKAIQLAMQAHCPLYIVHLSAKSSLEAVKKARHNGANVLVETCPQ 267

Query: 281 HLFLNSN 261
           +L L+ +
Sbjct: 268 YLLLDES 274


>UniRef50_Q6CUK0 Cluster: Similar to sp|P32375 Saccharomyces
           cerevisiae YIR027c DAL1 allantoinase singleton; n=1;
           Kluyveromyces lactis|Rep: Similar to sp|P32375
           Saccharomyces cerevisiae YIR027c DAL1 allantoinase
           singleton - Kluyveromyces lactis (Yeast) (Candida
           sphaerica)
          Length = 532

 Score = 41.5 bits (93), Expect = 0.025
 Identities = 18/43 (41%), Positives = 27/43 (62%)
 Frame = -2

Query: 377 VHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDITK 249
           VHI H+A  E + I+K AK+ G+ +T E C H+L L +  + K
Sbjct: 316 VHIVHLASMEALPILKRAKDMGLPITAETCFHYLSLAAERVPK 358


>UniRef50_A1CFB0 Cluster: Allantoinase Dal1, putative; n=11;
           Pezizomycotina|Rep: Allantoinase Dal1, putative -
           Aspergillus clavatus
          Length = 509

 Score = 41.5 bits (93), Expect = 0.025
 Identities = 17/42 (40%), Positives = 27/42 (64%)
 Frame = -2

Query: 380 PVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 255
           P+HI H++  E I +++ A+  GVK+T E C H+L L +  I
Sbjct: 257 PLHIVHLSAMEVIPLLREARANGVKITAETCFHYLSLAAEQI 298


>UniRef50_A2BJ21 Cluster: Dihydroorotase; n=1; Hyperthermus
           butylicus DSM 5456|Rep: Dihydroorotase - Hyperthermus
           butylicus (strain DSM 5456 / JCM 9403)
          Length = 424

 Score = 41.5 bits (93), Expect = 0.025
 Identities = 27/80 (33%), Positives = 40/80 (50%), Gaps = 1/80 (1%)
 Frame = -3

Query: 832 GNIVKLPGFIDVHVHVREPGANIKGRF*DLLPQXHWLVV-LTMICAMPNTNPSIVDRTAF 656
           G IV LPG ID+HVH+R  G  +  +  +           +T++  MPNT P +  ++A 
Sbjct: 48  GGIV-LPGMIDLHVHLR--GLKLSYKEDEATSTRAAAASGITLVADMPNTMPPLRSKSAI 104

Query: 655 DYASTLARVSARCDYALYVG 596
           D      R  +  DYA+Y G
Sbjct: 105 DAKLAALRRMSLVDYAVYAG 124


>UniRef50_Q2S0H8 Cluster: Dihydroorotase; n=1; Salinibacter ruber
           DSM 13855|Rep: Dihydroorotase - Salinibacter ruber
           (strain DSM 13855)
          Length = 430

 Score = 41.1 bits (92), Expect = 0.034
 Identities = 17/46 (36%), Positives = 27/46 (58%)
 Frame = -2

Query: 407 ILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFL 270
           I +A+     +H+ H++    + +++ AK  GV VT EVC HHL L
Sbjct: 220 IELAARTGGALHVAHISTARGVELVRRAKAHGVPVTAEVCTHHLTL 265



 Score = 41.1 bits (92), Expect = 0.034
 Identities = 29/74 (39%), Positives = 38/74 (51%), Gaps = 5/74 (6%)
 Frame = -1

Query: 231 KVCPVLCSPEDQAELWRNIS--IIDVFATDHAPHTVEEKNSE--NPPPGYPGLETILPLL 64
           K+ P L SP D A L   ++   ID   TDHAPH   EK  E  + P G  GLET   L+
Sbjct: 280 KMHPPLRSPADVAALKEGLADGTIDAICTDHAPHASYEKQVEFAHAPFGILGLETAWGLI 339

Query: 63  -LNAVHQGRLTIED 25
               +  G L++E+
Sbjct: 340 GRELIEPGVLSVEE 353



 Score = 33.5 bits (73), Expect = 6.8
 Identities = 18/55 (32%), Positives = 28/55 (50%)
 Frame = -3

Query: 814 PGFIDVHVHVREPGANIKGRF*DLLPQXHWLVVLTMICAMPNTNPSIVDRTAFDY 650
           PG++D+HVH+REPG   K        +       T +  MPNT+P +  R   ++
Sbjct: 57  PGWMDMHVHLREPGYEHKETV-ATGSRAALAGGFTDVACMPNTDPPLHTRDVVEF 110


>UniRef50_Q26E93 Cluster: Dihydroorotase; n=1; Flavobacteria
           bacterium BBFL7|Rep: Dihydroorotase - Flavobacteria
           bacterium BBFL7
          Length = 416

 Score = 41.1 bits (92), Expect = 0.034
 Identities = 22/69 (31%), Positives = 38/69 (55%)
 Frame = -2

Query: 458 KKMPVCTHAEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHH 279
           K MP    AE  + A  I +A+     +HI  +     + +IK AK++   ++C V  +H
Sbjct: 202 KTMPAI--AEEVQIARDIQVAAYTGARLHIPTITTAASVQLIKEAKKKYSNISCSVSTNH 259

Query: 278 LFLNSNDIT 252
           LFL++ND++
Sbjct: 260 LFLDTNDLS 268


>UniRef50_Q9UX05 Cluster: Dihydroorotase; n=5; Sulfolobaceae|Rep:
           Dihydroorotase - Sulfolobus solfataricus
          Length = 390

 Score = 41.1 bits (92), Expect = 0.034
 Identities = 23/70 (32%), Positives = 36/70 (51%), Gaps = 2/70 (2%)
 Frame = -1

Query: 231 KVCPVLCSPEDQAELWRNISIIDVFATDHAPHTVEEKNS--ENPPPGYPGLETILPLLLN 58
           KV P +    ++  L + I+ +D   +DHAPH   EK    E  PPG   L   +P +L 
Sbjct: 232 KVNPPIRDTNERLWLLQAINEVDTVVSDHAPHASFEKQQPYEICPPGIAALSFTVPFILT 291

Query: 57  AVHQGRLTIE 28
            V +G ++I+
Sbjct: 292 LVSKGIISID 301


>UniRef50_Q930B0 Cluster: Allantoinase, putative; n=1; Sinorhizobium
           meliloti|Rep: Allantoinase, putative - Rhizobium
           meliloti (Sinorhizobium meliloti)
          Length = 195

 Score = 40.7 bits (91), Expect = 0.045
 Identities = 28/90 (31%), Positives = 40/90 (44%), Gaps = 1/90 (1%)
 Frame = -3

Query: 826 IVKLPGFIDVHVHVREPGANIKGRF*DLLPQXHWLVVLTMICAMP-NTNPSIVDRTAFDY 650
           ++ LPG +D HVH  EPG      F +   +      +T    MP N  P+ +D  A   
Sbjct: 83  LLLLPGLVDAHVHFSEPGRGHWEGF-ETGSRAAAAGGITTFVEMPLNAQPATIDAAALVM 141

Query: 649 ASTLARVSARCDYALYVGASSTNYDTICEL 560
               A+ S   DYAL+ G    N D + +L
Sbjct: 142 KKAAAKQS-HIDYALWGGLVDDNLDDLADL 170


>UniRef50_A6DRU9 Cluster: Dihydroorotase; n=1; Lentisphaera araneosa
           HTCC2155|Rep: Dihydroorotase - Lentisphaera araneosa
           HTCC2155
          Length = 460

 Score = 40.7 bits (91), Expect = 0.045
 Identities = 19/65 (29%), Positives = 34/65 (52%)
 Frame = -2

Query: 434 AEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 255
           A    TA  + +    +    +CH +  + + +++AAKERGV VT E  P  L+ +++ +
Sbjct: 193 AANTATAFALYLIEKYELKGKLCHFSTGDGLELVRAAKERGVTVTVETTPQQLYWDTSSL 252

Query: 254 TKLEK 240
            K  K
Sbjct: 253 DKNNK 257


>UniRef50_Q6C0N2 Cluster: Similar to sp|P32375 Saccharomyces
           cerevisiae Allantoinase; n=1; Yarrowia lipolytica|Rep:
           Similar to sp|P32375 Saccharomyces cerevisiae
           Allantoinase - Yarrowia lipolytica (Candida lipolytica)
          Length = 457

 Score = 40.7 bits (91), Expect = 0.045
 Identities = 19/44 (43%), Positives = 26/44 (59%)
 Frame = -2

Query: 386 DRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 255
           D  +HI H+A  E + IIK AKE GV ++ E C H+L   +  I
Sbjct: 233 DVKLHIVHLATAEAVPIIKKAKEEGVPLSVETCFHYLHFAAESI 276


>UniRef50_Q8TXX9 Cluster: Dihydroorotase; n=1; Methanopyrus
           kandleri|Rep: Dihydroorotase - Methanopyrus kandleri
          Length = 426

 Score = 40.7 bits (91), Expect = 0.045
 Identities = 21/53 (39%), Positives = 31/53 (58%)
 Frame = -1

Query: 168 IDVFATDHAPHTVEEKNSENPPPGYPGLETILPLLLNAVHQGRLTIEDLLCRI 10
           +DV A+DHAPH +E++  E+ P G  G E ILP  L    +  L++ D +  I
Sbjct: 291 VDVLASDHAPHILEDE-FEDVPSGVTGGEIILPAALTLHRRFGLSLRDAVAMI 342



 Score = 33.9 bits (74), Expect = 5.1
 Identities = 21/55 (38%), Positives = 29/55 (52%), Gaps = 3/55 (5%)
 Frame = -2

Query: 422 KTAAVILMASLLDR---PVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLN 267
           +T AV L+A L  R    +H+ HV   E + I K     G  +T +V PHHLF +
Sbjct: 207 ETTAVGLLAGLKVRYPSRIHLSHVTLPESVKIAK-----GADITVDVTPHHLFFD 256


>UniRef50_Q1AVY7 Cluster: Dihydroorotase; n=1; Rubrobacter
           xylanophilus DSM 9941|Rep: Dihydroorotase - Rubrobacter
           xylanophilus (strain DSM 9941 / NBRC 16129)
          Length = 436

 Score = 40.3 bits (90), Expect = 0.059
 Identities = 24/54 (44%), Positives = 30/54 (55%), Gaps = 3/54 (5%)
 Frame = -1

Query: 171 IIDVFATDHAPHTVEEKN--SENPPPGYPGLETILPLLLNA-VHQGRLTIEDLL 19
           I+D  ATDHAPH  EEK    E   PG+ G ET    L    V +GRL++  L+
Sbjct: 302 ILDFVATDHAPHAPEEKELPLEEAAPGFLGHETAFAALYTGLVLEGRLSLGRLV 355


>UniRef50_Q4FLQ3 Cluster: Dihydroorotase; n=2; Candidatus
           Pelagibacter ubique|Rep: Dihydroorotase - Pelagibacter
           ubique
          Length = 428

 Score = 39.9 bits (89), Expect = 0.078
 Identities = 24/75 (32%), Positives = 37/75 (49%), Gaps = 4/75 (5%)
 Frame = -1

Query: 231 KVCPVLCSPEDQAELWRNIS--IIDVFATDHAPHTVEEKNSE--NPPPGYPGLETILPLL 64
           K+ P L + ED+  L + +    IDV  +DH P   E+K         G  G+ET+L L 
Sbjct: 281 KLSPPLRTEEDRIALVQGLKDETIDVIVSDHKPEDEEQKRLTFAQASTGASGIETLLSLS 340

Query: 63  LNAVHQGRLTIEDLL 19
           L   H G + +E ++
Sbjct: 341 LELYHNGSVKLETII 355


>UniRef50_Q18S74 Cluster: Amidohydrolase; n=2; Desulfitobacterium
           hafniense|Rep: Amidohydrolase - Desulfitobacterium
           hafniense (strain DCB-2)
          Length = 449

 Score = 39.9 bits (89), Expect = 0.078
 Identities = 18/62 (29%), Positives = 33/62 (53%)
 Frame = -2

Query: 431 EREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDIT 252
           E E  + +I  A      + I H++  + + ++  A+ RGV V CE   H+L+L  +D+ 
Sbjct: 218 EIENVSRMITFAEETGCKLIIAHISTAKAVELVAQARARGVDVYCETIGHYLYLTGDDVE 277

Query: 251 KL 246
           +L
Sbjct: 278 RL 279


>UniRef50_A6CS57 Cluster: Dihydropyrimidinase; n=1; Bacillus sp.
           SG-1|Rep: Dihydropyrimidinase - Bacillus sp. SG-1
          Length = 475

 Score = 39.9 bits (89), Expect = 0.078
 Identities = 20/70 (28%), Positives = 35/70 (50%)
 Frame = -2

Query: 431 EREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDIT 252
           E E T     +  L D  +++ HV+  E +  I +A+ +G+ V  E CP +L L+ + + 
Sbjct: 219 EGEATGRAAKLTGLADSQLYVVHVSCSEAVKQIASARSKGLNVWGETCPQYLVLDQSYLE 278

Query: 251 KLEKGEQKYV 222
           +      KYV
Sbjct: 279 RPNFEGAKYV 288


>UniRef50_Q6KZ43 Cluster: Dihydroorotase; n=2;
           Thermoplasmatales|Rep: Dihydroorotase - Picrophilus
           torridus
          Length = 408

 Score = 39.9 bits (89), Expect = 0.078
 Identities = 27/71 (38%), Positives = 38/71 (53%), Gaps = 3/71 (4%)
 Frame = -1

Query: 231 KVCPVLCSPEDQAELWRNI--SIIDVFATDHAPHTVEEKNS-ENPPPGYPGLETILPLLL 61
           KV P L S   Q+ L  +      D+ ++DHAPH+  EK   E   PG  G+ET +PL+L
Sbjct: 244 KVNPPLRSRSAQSLLLNSYISGNFDILSSDHAPHSQNEKTDFEYALPGIIGVETRIPLML 303

Query: 60  NAVHQGRLTIE 28
             V +  L I+
Sbjct: 304 ALVSKKILPID 314



 Score = 37.5 bits (83), Expect = 0.41
 Identities = 29/103 (28%), Positives = 40/103 (38%)
 Frame = -3

Query: 817 LPGFIDVHVHVREPGANIKGRF*DLLPQXHWLVVLTMICAMPNTNPSIVDRTAFDYASTL 638
           +P   D HVH R+PG   K  F             T I  MPN    I +  AF     +
Sbjct: 44  MPAGTDSHVHFRDPGETYKEDF-STGTMSAIFGGTTTIIDMPNNKIRIDNYQAFSDKLAI 102

Query: 637 ARVSARCDYALYVGASSTNYDTICELAPQAAALKMYLNETFTT 509
               A CD+ LY   S    D    +  ++  +K+Y+  T  T
Sbjct: 103 VSRKAYCDFGLY---SMFTGDNSLIIDKRSTGIKIYMGNTTNT 142


>UniRef50_Q2JMN8 Cluster: Dihydroorotase, putative; n=2;
           Synechococcus|Rep: Dihydroorotase, putative -
           Synechococcus sp. (strain JA-2-3B'a(2-13))
           (Cyanobacteria bacteriumYellowstone B-Prime)
          Length = 448

 Score = 39.1 bits (87), Expect = 0.14
 Identities = 29/70 (41%), Positives = 37/70 (52%), Gaps = 4/70 (5%)
 Frame = -1

Query: 231 KVCPVLCSPEDQAELWRNISIIDV-FATDHAPHTVEEKN--SENPPPGYPGLETILPLLL 61
           ++ P L S  D+  L   I   ++  ATDH P+T EEK     + PPG  GLE  LPLL 
Sbjct: 301 RLLPPLPSAGDREALIAGIRSGNLGIATDHHPYTYEEKTLPFADAPPGAMGLELALPLLW 360

Query: 60  -NAVHQGRLT 34
            + V  G LT
Sbjct: 361 HHLVETGSLT 370


>UniRef50_Q24PA5 Cluster: Putative uncharacterized protein; n=1;
           Desulfitobacterium hafniense Y51|Rep: Putative
           uncharacterized protein - Desulfitobacterium hafniense
           (strain Y51)
          Length = 446

 Score = 39.1 bits (87), Expect = 0.14
 Identities = 28/99 (28%), Positives = 46/99 (46%), Gaps = 2/99 (2%)
 Frame = -3

Query: 817 LPGFIDVHVHVREPGANIKGRF*DLLPQXHWLVVLTMICAMPNTNPSIVDRTAFDYASTL 638
           +PG ID H+H ++PG   +  F           + T + AMP TN  +VD   + + +  
Sbjct: 54  IPGAIDTHIHFQDPGRIYREDFEHATAACACGGITTGM-AMPTTN--LVDVEGYKFNTQT 110

Query: 637 ARVSARCDYALYVGASSTNYDTICELAPQA--AALKMYL 527
                  DYAL+     +N D + +L  Q    A+KM++
Sbjct: 111 YEGRGYIDYALHGAGRPSNVDQVEDLWTQTGITAIKMFM 149



 Score = 38.3 bits (85), Expect = 0.24
 Identities = 23/75 (30%), Positives = 39/75 (52%), Gaps = 7/75 (9%)
 Frame = -1

Query: 222 PVLCSPEDQAELWRNIS--IIDVFATDHAPHTVEEKNSE-----NPPPGYPGLETILPLL 64
           PV+   +++ ++W  +    IDV  +DH P    EK            G PGLE  LP L
Sbjct: 280 PVMRGEDNRLKMWELLEKGYIDVIGSDHCPAEKWEKEVALNDIWKTHYGIPGLEVYLPSL 339

Query: 63  LNAVHQGRLTIEDLL 19
           L+ V++G +++E ++
Sbjct: 340 LDGVNKGLVSLEKVV 354


>UniRef50_Q6BV31 Cluster: Similar to CA5801|CaDAL1 Candida albicans
           CaDAL1 allantoinase; n=2; Saccharomycetaceae|Rep:
           Similar to CA5801|CaDAL1 Candida albicans CaDAL1
           allantoinase - Debaryomyces hansenii (Yeast)
           (Torulaspora hansenii)
          Length = 648

 Score = 39.1 bits (87), Expect = 0.14
 Identities = 16/42 (38%), Positives = 27/42 (64%)
 Frame = -2

Query: 380 PVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 255
           P+HI H+A  E I +++AAK + + ++ E C H+L L +  I
Sbjct: 426 PLHIVHLATHEAIPLVRAAKAQNLPISAETCFHYLSLAAEKI 467


>UniRef50_P40757 Cluster: Allantoinase, mitochondrial precursor;
           n=1; Rana catesbeiana|Rep: Allantoinase, mitochondrial
           precursor - Rana catesbeiana (Bull frog)
          Length = 484

 Score = 39.1 bits (87), Expect = 0.14
 Identities = 28/84 (33%), Positives = 41/84 (48%), Gaps = 3/84 (3%)
 Frame = -2

Query: 497 DMTIWQKHFQSWPKKMPVCTHAEREKTAAVILMASLLDR---PVHICHVARKEEILIIKA 327
           D T++Q    S P  M +         AAV L+A L  +     HI H++  + + II+ 
Sbjct: 213 DSTLYQTFLDSRPDDMEI---------AAVQLVADLCQQYKVRCHIVHLSSAQSLTIIRK 263

Query: 326 AKERGVKVTCEVCPHHLFLNSNDI 255
           AKE G  +T E   H+L L+S  I
Sbjct: 264 AKEAGAPLTVETTHHYLSLSSEHI 287


>UniRef50_Q84FR6 Cluster: D-hydantoinase; n=1; Arthrobacter
           crystallopoietes|Rep: D-hydantoinase - Arthrobacter
           crystallopoietes
          Length = 457

 Score = 38.7 bits (86), Expect = 0.18
 Identities = 27/79 (34%), Positives = 41/79 (51%), Gaps = 9/79 (11%)
 Frame = -1

Query: 237 RAKVCPVLCSPEDQAELWRNISI--IDVFATDHAPHTVEEK------NSENPPPGYPGLE 82
           +A + P L + E Q  LWR I+   + V ++DH P   EEK      +    P G PG+E
Sbjct: 286 KAVLTPPLRTQEHQDALWRGINTGALSVVSSDHCPFCFEEKQRMGADDFRQIPNGGPGVE 345

Query: 81  -TILPLLLNAVHQGRLTIE 28
             +L +    V +G++TIE
Sbjct: 346 HRMLVMYETGVAEGKMTIE 364


>UniRef50_A6CCA9 Cluster: Dihydroorotase, multifunctional complex
           type; n=1; Planctomyces maris DSM 8797|Rep:
           Dihydroorotase, multifunctional complex type -
           Planctomyces maris DSM 8797
          Length = 426

 Score = 38.7 bits (86), Expect = 0.18
 Identities = 27/79 (34%), Positives = 39/79 (49%), Gaps = 5/79 (6%)
 Frame = -1

Query: 231 KVCPVLCSPEDQAELWRNIS--IIDVFATDHAPHTVEEKNSE--NPPPGYPGLETILPLL 64
           KV P L S E    L   +    ID   +DH PH  E+K  E      G  GLET+LP+ 
Sbjct: 276 KVLPPLRSQEHIDALIEGLKDGTIDAICSDHTPHAAEKKTDEILGADFGIIGLETLLPVC 335

Query: 63  LNA-VHQGRLTIEDLLCRI 10
           L + +  G L+  +L+ ++
Sbjct: 336 LQSLITPGHLSWPELIGKL 354



 Score = 37.9 bits (84), Expect = 0.31
 Identities = 23/84 (27%), Positives = 44/84 (52%)
 Frame = -3

Query: 826 IVKLPGFIDVHVHVREPGANIKGRF*DLLPQXHWLVVLTMICAMPNTNPSIVDRTAFDYA 647
           ++  PGFID+HV + EPG   +    +          +T +  +PNT+P + DR++ ++ 
Sbjct: 50  LIVSPGFIDIHVSLCEPGFE-EDETIESGTAAALAGGVTSLGCLPNTSPVVDDRSSAEFI 108

Query: 646 STLARVSARCDYALYVGASSTNYD 575
              A  +A C +   +GA + N++
Sbjct: 109 LLQAERAANC-HVYPLGAITKNHE 131



 Score = 35.9 bits (79), Expect = 1.3
 Identities = 15/46 (32%), Positives = 27/46 (58%)
 Frame = -2

Query: 407 ILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFL 270
           I +A L    +H+  ++ +  +  I+ AK  G++V+ +V PHHL L
Sbjct: 218 IALAELTRGRIHLMCISTQNSVSQIRRAKAAGIRVSADVTPHHLTL 263


>UniRef50_Q972W9 Cluster: 413aa long hypothetical D-hydantoinase;
           n=1; Sulfolobus tokodaii|Rep: 413aa long hypothetical
           D-hydantoinase - Sulfolobus tokodaii
          Length = 413

 Score = 38.7 bits (86), Expect = 0.18
 Identities = 19/51 (37%), Positives = 30/51 (58%), Gaps = 4/51 (7%)
 Frame = -1

Query: 201 DQAELWRNISIIDVFATDH--APHTVEEKNSENPP--PGYPGLETILPLLL 61
           D  E+W+ I+ + + ATDH      V+E + E P   PG PG+E  +P++L
Sbjct: 264 DPEEIWKRINKVSIIATDHNWFDKEVKENHKEFPDLVPGLPGVELRVPIIL 314


>UniRef50_P32375 Cluster: Allantoinase; n=3; Saccharomycetaceae|Rep:
           Allantoinase - Saccharomyces cerevisiae (Baker's yeast)
          Length = 460

 Score = 38.7 bits (86), Expect = 0.18
 Identities = 17/42 (40%), Positives = 26/42 (61%)
 Frame = -2

Query: 380 PVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 255
           PVHI H+A  + I +I+ A+  G+ VT E C H+L + +  I
Sbjct: 245 PVHIVHLASMKAIPLIRKARASGLPVTTETCFHYLCIAAEQI 286


>UniRef50_Q5NPE4 Cluster: Dihydroorotase; n=8; Sphingomonadales|Rep:
           Dihydroorotase - Zymomonas mobilis
          Length = 408

 Score = 38.3 bits (85), Expect = 0.24
 Identities = 25/77 (32%), Positives = 39/77 (50%), Gaps = 5/77 (6%)
 Frame = -1

Query: 234 AKVCPVLCSPEDQ---AELWRNISIIDVFATDHAPHTVEEKNSE--NPPPGYPGLETILP 70
           A++ P L   +D+    E  R+  +ID+F + H P   E+K     +  PG  G ET+L 
Sbjct: 262 ARLSPPLRGEDDRLASVEALRD-GVIDMFCSAHDPRDAEDKRLPFIDAKPGMAGAETLLS 320

Query: 69  LLLNAVHQGRLTIEDLL 19
             L  VHQG + +  L+
Sbjct: 321 ASLELVHQGVIDLSRLV 337



 Score = 35.1 bits (77), Expect = 2.2
 Identities = 18/56 (32%), Positives = 30/56 (53%)
 Frame = -2

Query: 434 AEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLN 267
           AE    A  +++A      +H   +  K+   +I+ AKE+GVKVT  + P +L L+
Sbjct: 196 AEAIVVARDLMLAEETGCKIHFAQLTTKKSFDLIRQAKEKGVKVTVGINPAYLLLS 251


>UniRef50_Q31EK1 Cluster: Aspartate carbamoyltransferase,
           non-catalytic chain; n=1; Thiomicrospira crunogena
           XCL-2|Rep: Aspartate carbamoyltransferase, non-catalytic
           chain - Thiomicrospira crunogena (strain XCL-2)
          Length = 428

 Score = 38.3 bits (85), Expect = 0.24
 Identities = 19/60 (31%), Positives = 30/60 (50%)
 Frame = -2

Query: 434 AEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 255
           AE    A  +++A      VH   ++    + +I  AK+RG+ VTC+V  H L L   D+
Sbjct: 211 AETAALARDLILAEETGARVHFSQISTARSLEMIADAKKRGMPVTCDVAIHQLHLTEYDV 270



 Score = 37.1 bits (82), Expect = 0.55
 Identities = 25/70 (35%), Positives = 34/70 (48%), Gaps = 4/70 (5%)
 Frame = -1

Query: 228 VCPVLCSPEDQAELWRNIS--IIDVFATDHAP--HTVEEKNSENPPPGYPGLETILPLLL 61
           V P L + +D+  L   +   IID   +DH P    V+        PG  GLET+LPL L
Sbjct: 279 VTPPLRTHDDKEALRLGVKMGIIDAIVSDHTPLDRDVKLLPFGESEPGISGLETLLPLTL 338

Query: 60  NAVHQGRLTI 31
             V +G L +
Sbjct: 339 RLVEEGVLDL 348



 Score = 36.3 bits (80), Expect = 0.96
 Identities = 27/96 (28%), Positives = 47/96 (48%), Gaps = 2/96 (2%)
 Frame = -3

Query: 817 LPGFIDVHVHVREPGANIKGRF*DLLPQXHWLVV--LTMICAMPNTNPSIVDRTAFDYAS 644
           LPG +D+H  + EPG+  +G   ++  +    V   +T IC+ P+TNP    +   +   
Sbjct: 55  LPGLVDLHARLAEPGSRYEG---NIASETKAAVSGGITTICSPPDTNPVNDTQAVTELIQ 111

Query: 643 TLARVSARCDYALYVGASSTNYDTICELAPQAAALK 536
             AR +A   + L +GA +   +   ++    AALK
Sbjct: 112 RRARQAATA-FVLPIGALTQGLEG--KMLSNMAALK 144


>UniRef50_A1A2Z8 Cluster: Putative allantoinase; n=3;
           Bifidobacterium adolescentis|Rep: Putative allantoinase
           - Bifidobacterium adolescentis (strain ATCC 15703 / DSM
           20083)
          Length = 278

 Score = 38.3 bits (85), Expect = 0.24
 Identities = 20/67 (29%), Positives = 34/67 (50%), Gaps = 2/67 (2%)
 Frame = -2

Query: 449 PVCTHAEREKTAA--VILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHL 276
           P    AE E  A   ++ + +      HI HV+    + +++ AK  G+ V+ E CPH+L
Sbjct: 46  PASRPAECEANAVRKIVRLVARTGCRTHILHVSSGLSVDVLRRAKAEGLPVSAETCPHYL 105

Query: 275 FLNSNDI 255
            L+ + I
Sbjct: 106 TLDCDHI 112


>UniRef50_Q2GR02 Cluster: Putative uncharacterized protein; n=4;
           Sordariomycetes|Rep: Putative uncharacterized protein -
           Chaetomium globosum (Soil fungus)
          Length = 593

 Score = 38.3 bits (85), Expect = 0.24
 Identities = 18/53 (33%), Positives = 34/53 (64%), Gaps = 1/53 (1%)
 Frame = -2

Query: 410 VILMASLLDR-PVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 255
           ++ MA L  +  +HI H++  E + I++ A++ G+ +T E C H+L L S++I
Sbjct: 253 ILSMAHLAPQLHLHIVHLSATECVPILRKARQDGINITAETCFHYLGLASDNI 305


>UniRef50_Q31R01 Cluster: Dihydroorotase and related cyclic
           amidohydrolases-like; n=2; Synechococcus elongatus|Rep:
           Dihydroorotase and related cyclic amidohydrolases-like -
           Synechococcus sp. (strain PCC 7942) (Anacystis nidulans
           R2)
          Length = 411

 Score = 37.9 bits (84), Expect = 0.31
 Identities = 20/63 (31%), Positives = 35/63 (55%), Gaps = 3/63 (4%)
 Frame = -2

Query: 431 EREKTAAVILMASLLD---RPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSN 261
           +  +TAA+ L+  LL     P+H+  V+    + +I  A++RG+ +T  V   HL  N+ 
Sbjct: 204 QSSETAALALLLELLADCLTPIHLMRVSTARSVELIAQAQQRGLPITASVTWLHLLGNTA 263

Query: 260 DIT 252
           D+T
Sbjct: 264 DLT 266



 Score = 36.3 bits (80), Expect = 0.96
 Identities = 22/60 (36%), Positives = 30/60 (50%), Gaps = 4/60 (6%)
 Frame = -1

Query: 231 KVCPVLCSPEDQAELWRNIS--IIDVFATDHAPHTVEEKNSE--NPPPGYPGLETILPLL 64
           ++ P L  PE+Q  L + +   +I   A DH+P+  EEK       P G  GLE  LP L
Sbjct: 273 RLAPPLPEPEEQLALQQAVQEGVITAIAVDHSPYLYEEKTVAFGEAPAGAIGLELALPQL 332


>UniRef50_A5KJ64 Cluster: Putative uncharacterized protein; n=1;
           Ruminococcus torques ATCC 27756|Rep: Putative
           uncharacterized protein - Ruminococcus torques ATCC
           27756
          Length = 455

 Score = 37.9 bits (84), Expect = 0.31
 Identities = 24/82 (29%), Positives = 36/82 (43%)
 Frame = -2

Query: 434 AEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 255
           AE E    ++ +A   D PV I +++       I  A+E G  V  E CP +L LN    
Sbjct: 215 AEAEAVGRILKIAKCADVPVIIVNLSTAAGYREILKAREIGQTVYVETCPEYLLLNEEKY 274

Query: 254 TKLEKGEQKYVQYYVVLKTKQN 189
               +  +KYV    + K K +
Sbjct: 275 ALAAEEARKYVTVPPLRKQKNS 296


>UniRef50_Q259B7 Cluster: H0901F07.3 protein; n=12;
           Magnoliophyta|Rep: H0901F07.3 protein - Oryza sativa
           (Rice)
          Length = 497

 Score = 37.9 bits (84), Expect = 0.31
 Identities = 14/42 (33%), Positives = 28/42 (66%), Gaps = 1/42 (2%)
 Frame = -2

Query: 377 VHICHVA-RKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 255
           +HI H++  K  + ++K AK+ G +V+ E CPH+L  ++ ++
Sbjct: 280 IHIVHLSDAKTSLGLLKDAKQNGARVSVETCPHYLAFSAEEV 321


>UniRef50_Q5PR45 Cluster: Zgc:103559; n=8; Eumetazoa|Rep: Zgc:103559
           - Danio rerio (Zebrafish) (Brachydanio rerio)
          Length = 459

 Score = 37.5 bits (83), Expect = 0.41
 Identities = 16/40 (40%), Positives = 26/40 (65%)
 Frame = -2

Query: 374 HICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 255
           HI H++  E + +I+AAK+ G  +T E   H+L L++ DI
Sbjct: 238 HIVHLSSAEPLELIRAAKQAGAPLTVETTHHYLNLSAEDI 277


>UniRef50_Q8EW20 Cluster: Dihydroorotase; n=1; Mycoplasma
           penetrans|Rep: Dihydroorotase - Mycoplasma penetrans
          Length = 422

 Score = 37.5 bits (83), Expect = 0.41
 Identities = 20/55 (36%), Positives = 31/55 (56%), Gaps = 3/55 (5%)
 Frame = -1

Query: 168 IDVFATDHAPHTVEEKNSENPPPGYPGLETILPLLLNAVHQGRLTI---EDLLCR 13
           ID+  +DH P ++ EK  E    G P  ET+  +L ++ +  R+ I   EDLLC+
Sbjct: 272 IDIITSDHTPVSLIEK-FETEQKGLPNFETMFSILFDSCYYKRIPITILEDLLCK 325


>UniRef50_A3DM45 Cluster: Amidohydrolase; n=1; Staphylothermus
           marinus F1|Rep: Amidohydrolase - Staphylothermus marinus
           (strain ATCC 43588 / DSM 3639 / F1)
          Length = 430

 Score = 37.5 bits (83), Expect = 0.41
 Identities = 19/51 (37%), Positives = 30/51 (58%), Gaps = 2/51 (3%)
 Frame = -1

Query: 168 IDVFATDHAPHTVEEKN--SENPPPGYPGLETILPLLLNAVHQGRLTIEDL 22
           ID  A+DHAPH+V EK    +  PPG  G+E I     + V +G ++++ +
Sbjct: 287 IDALASDHAPHSVVEKMCCPKTCPPGINGVEVISVFAGDLVSKGIISLDQM 337



 Score = 36.3 bits (80), Expect = 0.96
 Identities = 21/84 (25%), Positives = 40/84 (47%)
 Frame = -3

Query: 826 IVKLPGFIDVHVHVREPGANIKGRF*DLLPQXHWLVVLTMICAMPNTNPSIVDRTAFDYA 647
           ++  PGFID+HVH+R+   + K    +   +      +T++  MPNT P I + +  +  
Sbjct: 53  VIAFPGFIDMHVHLRDFKQSYKETI-ETGTKAALHGGITVVGEMPNTLPRIDNFSILEKR 111

Query: 646 STLARVSARCDYALYVGASSTNYD 575
             +   ++  DY +Y+       D
Sbjct: 112 MKILENNSYTDYYVYIDVPENKSD 135


>UniRef50_Q8G657 Cluster: Dihydroorotase; n=4; Bifidobacterium|Rep:
           Dihydroorotase - Bifidobacterium longum
          Length = 498

 Score = 37.1 bits (82), Expect = 0.55
 Identities = 16/43 (37%), Positives = 23/43 (53%)
 Frame = -2

Query: 377 VHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDITK 249
           VH  HV+       I+ AK  G+ +TCE  PH+L L+   + K
Sbjct: 258 VHFQHVSTAISFEAIRRAKAEGLPITCETAPHYLALSDEALLK 300



 Score = 34.3 bits (75), Expect = 3.9
 Identities = 23/55 (41%), Positives = 29/55 (52%), Gaps = 4/55 (7%)
 Frame = -1

Query: 234 AKVCPVLCSPEDQAELWRNIS--IIDVFATDHAPHTVEEKNSE--NPPPGYPGLE 82
           AK+ P L S  D+      I+   +D+ ATDHAPHT+ EK       P G  GLE
Sbjct: 305 AKMNPPLRSEADRKATIAAIADGTVDLLATDHAPHTLAEKELGFLEAPNGIIGLE 359


>UniRef50_A6NQ76 Cluster: Putative uncharacterized protein; n=1;
           Bacteroides capillosus ATCC 29799|Rep: Putative
           uncharacterized protein - Bacteroides capillosus ATCC
           29799
          Length = 472

 Score = 37.1 bits (82), Expect = 0.55
 Identities = 16/57 (28%), Positives = 30/57 (52%)
 Frame = -2

Query: 431 EREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSN 261
           E E     + ++ +   PV++ H++    + +I+AA+ RG K   E CP +  LN +
Sbjct: 228 EAEAVNRWLALSEMAGYPVNVVHLSTLRGLEVIRAARARGQKCYVESCPQYFLLNED 284


>UniRef50_A6G7W0 Cluster: Dihydroorotase and related cyclic
           amidoHydrolase; n=1; Plesiocystis pacifica SIR-1|Rep:
           Dihydroorotase and related cyclic amidoHydrolase -
           Plesiocystis pacifica SIR-1
          Length = 438

 Score = 37.1 bits (82), Expect = 0.55
 Identities = 16/41 (39%), Positives = 24/41 (58%)
 Frame = -2

Query: 377 VHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 255
           VHI H++    I +I  A+  G+ V+ E CPH+L L +  I
Sbjct: 221 VHIVHLSAASAIPVIAQARAEGLGVSVETCPHYLSLAAESI 261


>UniRef50_Q9YFI5 Cluster: Dihydroorotase; n=1; Aeropyrum pernix|Rep:
           Dihydroorotase - Aeropyrum pernix
          Length = 425

 Score = 37.1 bits (82), Expect = 0.55
 Identities = 28/98 (28%), Positives = 43/98 (43%), Gaps = 2/98 (2%)
 Frame = -3

Query: 817 LPGFIDVHVHVREPGANIKGRF*DLLPQXHWLV-VLTMICAMPNTNPSIVDRTAFDYAST 641
           LPG ID+HVH+R  G  +  +  ++          +T++  MPNT P +    A      
Sbjct: 54  LPGVIDMHVHLR--GLKLSYKEDEVSGTAAAASGCVTLVADMPNTQPPLRTPEALREKLA 111

Query: 640 LARVSARCDYALYVGASSTNYDTICELAPQA-AALKMY 530
                A+ DY +Y G    +Y    E+A    A  K+Y
Sbjct: 112 SLEAGAKVDYTVYAGV-PRSYGEAVEMASMGIAGFKIY 148



 Score = 34.7 bits (76), Expect = 2.9
 Identities = 15/32 (46%), Positives = 21/32 (65%), Gaps = 2/32 (6%)
 Frame = -1

Query: 171 IIDVFATDHAPHTVEEK--NSENPPPGYPGLE 82
           ++D  A+DHAPH+  EK  +    PPG+P LE
Sbjct: 286 LVDAIASDHAPHSTWEKWMHPAIAPPGFPWLE 317


>UniRef50_Q30S48 Cluster: Amidohydrolase; n=1; Thiomicrospira
           denitrificans ATCC 33889|Rep: Amidohydrolase -
           Thiomicrospira denitrificans (strain ATCC 33889 / DSM
           1351)
          Length = 399

 Score = 36.7 bits (81), Expect = 0.72
 Identities = 18/38 (47%), Positives = 23/38 (60%)
 Frame = -2

Query: 362 VARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDITK 249
           +A    I +I  AK  GV VTCEV  HH+ LNS++  K
Sbjct: 222 IASPRSIYLINKAKSEGVNVTCEVSIHHI-LNSDESCK 258


>UniRef50_Q08M50 Cluster: Allantoinase; n=1; Stigmatella aurantiaca
           DW4/3-1|Rep: Allantoinase - Stigmatella aurantiaca
           DW4/3-1
          Length = 311

 Score = 36.7 bits (81), Expect = 0.72
 Identities = 17/61 (27%), Positives = 31/61 (50%)
 Frame = -2

Query: 437 HAEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSND 258
           H E +    ++ +  L    VHI H++  + +  I AA+  G+  + E CPH+L  ++  
Sbjct: 73  HWEDDAIRMMVELCRLHRTRVHIVHLSSSDALPDIAAARREGLPFSVETCPHYLTFDAEH 132

Query: 257 I 255
           I
Sbjct: 133 I 133


>UniRef50_A5ZUT5 Cluster: Putative uncharacterized protein; n=1;
           Ruminococcus obeum ATCC 29174|Rep: Putative
           uncharacterized protein - Ruminococcus obeum ATCC 29174
          Length = 457

 Score = 36.7 bits (81), Expect = 0.72
 Identities = 17/61 (27%), Positives = 30/61 (49%)
 Frame = -2

Query: 431 EREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDIT 252
           E E    ++++A   D PV + H+  K+    +  A+  G +V  E CP +L L+ +   
Sbjct: 216 EAEAVHRLLVIAKEADAPVMVVHLTNKKAFEEVMRARANGQEVYAETCPQYLLLDDSVYA 275

Query: 251 K 249
           K
Sbjct: 276 K 276


>UniRef50_Q1ERB5 Cluster: L-hydantoinase HyuH; n=1; uncultured
           crenarchaeote 31-F-01|Rep: L-hydantoinase HyuH -
           uncultured crenarchaeote 31-F-01
          Length = 486

 Score = 36.7 bits (81), Expect = 0.72
 Identities = 32/99 (32%), Positives = 50/99 (50%), Gaps = 26/99 (26%)
 Frame = -1

Query: 237 RAKVCPVLCSPEDQAELWRNIS--IIDVFATDHAPHTVEEK------------NSENPPP 100
           R KV P L S +D A +W  IS  +ID   +DH  + ++ K            +S N   
Sbjct: 295 RGKVVPPLRSKDDVAMVWDAISNGLIDCIGSDHVANRLDMKLGSGSCGGSSIGSSSNDGD 354

Query: 99  G-----------YPGLETILPLLLN-AVHQGRLTIEDLL 19
           G           +PG+ TILP++L+  V++GR+T+E L+
Sbjct: 355 GSDGDVWSALAGFPGIATILPVMLSEGVNKGRITLERLV 393


>UniRef50_Q2KUT6 Cluster: Dihydroorotase precursor; n=1; Bordetella
           avium 197N|Rep: Dihydroorotase precursor - Bordetella
           avium (strain 197N)
          Length = 390

 Score = 36.3 bits (80), Expect = 0.96
 Identities = 13/41 (31%), Positives = 25/41 (60%)
 Frame = -2

Query: 377 VHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 255
           +H+C ++    + +++AA+  G+ VT ++  HHL L   DI
Sbjct: 193 LHLCRLSSAAGVALLRAARAEGLPVTADISIHHLHLTDLDI 233


>UniRef50_A6LUW0 Cluster: Dihydropyrimidinase; n=1; Clostridium
           beijerinckii NCIMB 8052|Rep: Dihydropyrimidinase -
           Clostridium beijerinckii NCIMB 8052
          Length = 458

 Score = 36.3 bits (80), Expect = 0.96
 Identities = 20/74 (27%), Positives = 39/74 (52%), Gaps = 2/74 (2%)
 Frame = -2

Query: 437 HAEREKTAAVILMASLL-DRPVHICHVARKEEILIIKAAKERGVK-VTCEVCPHHLFLNS 264
           H E E  + V+ +A+L  D P++I H++ ++ +  I+ A+ +G K +  E C  +L +  
Sbjct: 212 HCEAEAISRVLHLAALAGDAPIYIVHISTEKGLDEIRKARAQGQKNIFSETCTQYLTMTE 271

Query: 263 NDITKLEKGEQKYV 222
               + +    KYV
Sbjct: 272 KKYLEPDNNGLKYV 285


>UniRef50_Q97C35 Cluster: Dihydroorotase; n=2; Thermoplasma|Rep:
           Dihydroorotase - Thermoplasma volcanium
          Length = 415

 Score = 36.3 bits (80), Expect = 0.96
 Identities = 19/49 (38%), Positives = 30/49 (61%), Gaps = 1/49 (2%)
 Frame = -1

Query: 165 DVFATDHAPHTVEEK-NSENPPPGYPGLETILPLLLNAVHQGRLTIEDL 22
           D+ ++DHAPHT ++K   E    G  G+ET +PL+L  V +  L ++ L
Sbjct: 273 DILSSDHAPHTEKDKAEFEYAKSGIIGVETRIPLMLALVKKKILFLDVL 321



 Score = 33.5 bits (73), Expect = 6.8
 Identities = 29/97 (29%), Positives = 42/97 (43%)
 Frame = -3

Query: 817 LPGFIDVHVHVREPGANIKGRF*DLLPQXHWLVVLTMICAMPNTNPSIVDRTAFDYASTL 638
           LP   D+HVH R PG   K  F             T++  MPN    I D  AF     +
Sbjct: 47  LPAATDIHVHFRTPGETDKEDF-STGSLSAIFGGTTLVMDMPNNIIPIKDYNAFSDKLGV 105

Query: 637 ARVSARCDYALYVGASSTNYDTICELAPQAAALKMYL 527
              ++  D+ALY   + +N   I +   ++  LK+YL
Sbjct: 106 INGTSYSDFALYSMETGSN-SLIVD--SRSIGLKVYL 139


>UniRef50_Q4T977 Cluster: Chromosome undetermined SCAF7631, whole
           genome shotgun sequence; n=9; Euteleostomi|Rep:
           Chromosome undetermined SCAF7631, whole genome shotgun
           sequence - Tetraodon nigroviridis (Green puffer)
          Length = 258

 Score = 35.9 bits (79), Expect = 1.3
 Identities = 18/52 (34%), Positives = 28/52 (53%), Gaps = 2/52 (3%)
 Frame = -1

Query: 258 HYKIGKGRAKVCPVLCSPEDQAELWRNISI--IDVFATDHAPHTVEEKNSEN 109
           H   G  + K CP +    +QA+LW  +    ID+  +DH+P T + KN E+
Sbjct: 74  HIPAGATQFKCCPPIRDSINQAQLWSALKAGHIDMVVSDHSPCTPDLKNLES 125


>UniRef50_Q7WMP7 Cluster: Dihydroorotase-like protein; n=3;
           Bordetella|Rep: Dihydroorotase-like protein - Bordetella
           bronchiseptica (Alcaligenes bronchisepticus)
          Length = 457

 Score = 35.9 bits (79), Expect = 1.3
 Identities = 23/77 (29%), Positives = 38/77 (49%), Gaps = 5/77 (6%)
 Frame = -1

Query: 234 AKVCPVLCSPEDQAELWRNI--SIIDVFATDHAPH--TVEEKNSENPPPGYPGLETILPL 67
           AKV P + S  D   +W  +    I    +DH P     ++K+      G+PG   ILP+
Sbjct: 288 AKVNPPVRSAADIDAMWEGVCDGAITTIGSDHVPRKRATKDKDIWAASNGFPGTGMILPI 347

Query: 66  LLN-AVHQGRLTIEDLL 19
           LL+   H+ ++ +E L+
Sbjct: 348 LLHEGYHRRQVPLETLM 364



 Score = 35.5 bits (78), Expect = 1.7
 Identities = 19/69 (27%), Positives = 33/69 (47%), Gaps = 2/69 (2%)
 Frame = -2

Query: 467 SWPKKMPVCTHAEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERG--VKVTCE 294
           +W ++ P     E E    V   A     PV+I H++ +E +  ++  +  G    +  E
Sbjct: 213 AWNEQSP--DFLEAENVHRVCYFAGKTGTPVNIVHLSSREALREVRRHRHEGRAAPIYVE 270

Query: 293 VCPHHLFLN 267
            CPH+LFL+
Sbjct: 271 TCPHYLFLD 279


>UniRef50_Q47RB7 Cluster: Allantoinase; n=1; Thermobifida fusca
           YX|Rep: Allantoinase - Thermobifida fusca (strain YX)
          Length = 474

 Score = 35.9 bits (79), Expect = 1.3
 Identities = 19/60 (31%), Positives = 29/60 (48%)
 Frame = -2

Query: 434 AEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 255
           AER     V+  A      VHI      E   I+ AA++ G+ V+ + CPH+L L +  +
Sbjct: 254 AERRGLERVLAAARSSGARVHISPFVAAECAAILAAARDIGIPVSAQTCPHYLCLPAEHV 313


>UniRef50_A4CLI6 Cluster: Dihydroorotase, multifunctional complex
           type; n=3; Flavobacteriaceae|Rep: Dihydroorotase,
           multifunctional complex type - Robiginitalea biformata
           HTCC2501
          Length = 417

 Score = 35.9 bits (79), Expect = 1.3
 Identities = 28/79 (35%), Positives = 37/79 (46%), Gaps = 4/79 (5%)
 Frame = -1

Query: 231 KVCPVLCSPEDQAELWRNIS--IIDVFATDHAPHTVEEKNSENPPPGYP--GLETILPLL 64
           KV P L + +D+  L + ++  IID   TDH P  +EEK  E     Y   GLE+   +L
Sbjct: 278 KVLPPLRTKKDRKALQKALAENIIDFVTTDHNPMDIEEKRQEFDRAAYGTLGLESAFGIL 337

Query: 63  LNAVHQGRLTIEDLLCRIR 7
                  R    D LCR R
Sbjct: 338 NKLFGTDRAV--DFLCRGR 354


>UniRef50_A0K2C1 Cluster: Dihydropyrimidinase; n=1; Arthrobacter sp.
           FB24|Rep: Dihydropyrimidinase - Arthrobacter sp. (strain
           FB24)
          Length = 479

 Score = 35.9 bits (79), Expect = 1.3
 Identities = 21/76 (27%), Positives = 37/76 (48%), Gaps = 7/76 (9%)
 Frame = -1

Query: 225 CPVLCSPEDQAELWRNIS--IIDVFATDHAPHTVEEKNSENP-----PPGYPGLETILPL 67
           CP + SPE  A L   ++   I   ++DH+ + + +K          P G PG+ET +P+
Sbjct: 291 CPPMRSPETVAALKERLADGAIHTVSSDHSCYDLSQKRERTDDIRAMPHGLPGVETRMPV 350

Query: 66  LLNAVHQGRLTIEDLL 19
              A+     ++ED +
Sbjct: 351 TFTAMASAGSSVEDFV 366



 Score = 34.7 bits (76), Expect = 2.9
 Identities = 16/56 (28%), Positives = 26/56 (46%)
 Frame = -2

Query: 434 AEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLN 267
           AE       + MA     PV+  H +    + ++  A+ RG +   E CPH+L L+
Sbjct: 221 AEEISVKETLAMAEYTKAPVYFVHQSTPGAVDLVTEARARGQEAFSETCPHYLTLD 276


>UniRef50_Q972L4 Cluster: 464aa long hypothetical D-hydantoinase;
           n=1; Sulfolobus tokodaii|Rep: 464aa long hypothetical
           D-hydantoinase - Sulfolobus tokodaii
          Length = 464

 Score = 35.9 bits (79), Expect = 1.3
 Identities = 24/68 (35%), Positives = 35/68 (51%), Gaps = 10/68 (14%)
 Frame = -1

Query: 237 RAKVCPVLCSPEDQAELWRNISIIDVFA--TDHAPHTVEEKNS--ENPPP------GYPG 88
           R  + P L S E + +LW  ++  D+F   +DH  ++  +K    E  PP      G PG
Sbjct: 285 RYVMSPPLRSDEQRTKLWMRLASGDIFTVGSDHCVYSDAQKKRYREEVPPFHEIPNGVPG 344

Query: 87  LETILPLL 64
            ETILP+L
Sbjct: 345 TETILPIL 352


>UniRef50_Q7UNR2 Cluster: Putative dihydroorotase; n=1; Pirellula
           sp.|Rep: Putative dihydroorotase - Rhodopirellula
           baltica
          Length = 456

 Score = 35.9 bits (79), Expect = 1.3
 Identities = 18/56 (32%), Positives = 28/56 (50%)
 Frame = -2

Query: 440 THAEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLF 273
           T AE    A  + +A      +H+  V+    I +I   K RG+ ++  VCPH+LF
Sbjct: 230 TEAEDLAVARDVRLAEATKGRLHVGPVSTMGSIDMIGRVKSRGIHISASVCPHNLF 285


>UniRef50_Q59699 Cluster: D-hydantoinase; n=11; Proteobacteria|Rep:
           D-hydantoinase - Pseudomonas putida
          Length = 495

 Score = 35.9 bits (79), Expect = 1.3
 Identities = 17/60 (28%), Positives = 32/60 (53%)
 Frame = -2

Query: 440 THAEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSN 261
           +  E E  +  I +A  +  P+++ H++ +E +  I  A+ +G  V  EV P HL L+ +
Sbjct: 214 SQVEGEAASRAIRIAETIGTPLYVVHISSREALDEITYARAKGQPVYGEVLPGHLLLDDS 273


>UniRef50_Q1AZI1 Cluster: D-hydantoinase; n=1; Rubrobacter
           xylanophilus DSM 9941|Rep: D-hydantoinase - Rubrobacter
           xylanophilus (strain DSM 9941 / NBRC 16129)
          Length = 467

 Score = 35.5 bits (78), Expect = 1.7
 Identities = 22/70 (31%), Positives = 33/70 (47%)
 Frame = -2

Query: 431 EREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDIT 252
           E E T   I +A +   P+ + HV+    +  I  A E G  V  E CP +L L+ +D+ 
Sbjct: 218 EAEATNRAIQLAEVAGCPLLVVHVSCAAALEEIHRAHELGQTVYAETCPQYLALSYDDLC 277

Query: 251 KLEKGEQKYV 222
           +      KYV
Sbjct: 278 REGFEGAKYV 287


>UniRef50_Q0VTM6 Cluster: Dihydroorotase, multifunctional complex
           type; n=1; Alcanivorax borkumensis SK2|Rep:
           Dihydroorotase, multifunctional complex type -
           Alcanivorax borkumensis (strain SK2 / ATCC 700651 / DSM
           11573)
          Length = 443

 Score = 35.5 bits (78), Expect = 1.7
 Identities = 23/70 (32%), Positives = 34/70 (48%), Gaps = 4/70 (5%)
 Frame = -1

Query: 228 VCPVLCSPEDQAELWRNIS--IIDVFATDHAPHTVEEKNSENPP--PGYPGLETILPLLL 61
           V P L S ED+  L   ++   ID   + H P     K +  P   PG  GL+ +L L+L
Sbjct: 297 VIPPLRSAEDRQALLEAVADGTIDAICSQHTPIGSSSKAAPFPTTKPGMAGLDVLLSLVL 356

Query: 60  NAVHQGRLTI 31
             V +G+L +
Sbjct: 357 QLVDEGKLDL 366



 Score = 34.3 bits (75), Expect = 3.9
 Identities = 16/58 (27%), Positives = 30/58 (51%)
 Frame = -2

Query: 434 AEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSN 261
           AE    +  +L+        H   ++ ++ + ++KAAK RG+ VT +V   HL L+ +
Sbjct: 229 AESVDLSRDLLLVEATGVRAHFQQISSRDSLRLLKAAKRRGLPVTADVSIQHLLLDES 286


>UniRef50_A6VSQ0 Cluster: Dihydroorotase, multifunctional complex
           type; n=4; Gammaproteobacteria|Rep: Dihydroorotase,
           multifunctional complex type - Marinomonas sp. MWYL1
          Length = 425

 Score = 35.5 bits (78), Expect = 1.7
 Identities = 24/78 (30%), Positives = 34/78 (43%), Gaps = 4/78 (5%)
 Frame = -1

Query: 240 GRAKVCPVLCSPEDQAELWRNIS--IIDVFATDHAPHTVEEKNSE--NPPPGYPGLETIL 73
           G   V P L S ED+  L   I   +I    +DH PH    K +      PG   +E +L
Sbjct: 274 GHFHVLPPLRSDEDRLTLIEGIKAGVISAICSDHQPHEKMAKIAPFAATEPGMANVEILL 333

Query: 72  PLLLNAVHQGRLTIEDLL 19
           PL +  + +G L    +L
Sbjct: 334 PLAMQLMDEGDLDFSTVL 351


>UniRef50_A3HYA6 Cluster: Dihydroorotase and related cyclic
           amidohydrolase; n=1; Algoriphagus sp. PR1|Rep:
           Dihydroorotase and related cyclic amidohydrolase -
           Algoriphagus sp. PR1
          Length = 413

 Score = 35.5 bits (78), Expect = 1.7
 Identities = 14/41 (34%), Positives = 24/41 (58%)
 Frame = -2

Query: 377 VHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 255
           VH   ++  + + +I+ AKE G+ VTC+V  + L    ND+
Sbjct: 227 VHFQTISSAKAVSLIRQAKEEGLNVTCDVSIYQLLFTDNDL 267


>UniRef50_A4R534 Cluster: Putative uncharacterized protein; n=1;
           Magnaporthe grisea|Rep: Putative uncharacterized protein
           - Magnaporthe grisea (Rice blast fungus) (Pyricularia
           grisea)
          Length = 297

 Score = 35.5 bits (78), Expect = 1.7
 Identities = 18/55 (32%), Positives = 32/55 (58%), Gaps = 1/55 (1%)
 Frame = -2

Query: 521 NFYNFLLEDMTIWQKHFQSWPKKMPVCTHAEREKTAAVILMASLLDRPV-HICHV 360
           ++YN L   +  W+K FQ+WP+K+ V +HA + K   V    S +  P+ H+ ++
Sbjct: 127 SYYNVLFAIIAFWRK-FQTWPEKLTVVSHAFK-KARIVEAHCSAIGFPIEHVNYI 179


>UniRef50_Q972X8 Cluster: 433aa long hypothetical D-hydantoinase;
           n=1; Sulfolobus tokodaii|Rep: 433aa long hypothetical
           D-hydantoinase - Sulfolobus tokodaii
          Length = 433

 Score = 35.5 bits (78), Expect = 1.7
 Identities = 15/57 (26%), Positives = 28/57 (49%)
 Frame = -2

Query: 431 EREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSN 261
           E E      ++A L     +I H++    + II   +++G K+  E CPH+L  + +
Sbjct: 210 EEEAVNRASMLAYLTGAKTYIVHISSPTSLDIISYWRKKGAKIFSETCPHYLLFDDS 266


>UniRef50_Q45515 Cluster: D-hydantoinase; n=14; Bacteria|Rep:
           D-hydantoinase - Bacillus stearothermophilus
           (Geobacillus stearothermophilus)
          Length = 471

 Score = 35.5 bits (78), Expect = 1.7
 Identities = 19/70 (27%), Positives = 33/70 (47%)
 Frame = -2

Query: 431 EREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDIT 252
           E E T     +  L    +++ HV+  + +  I  A+ +G+ V  E CP +L L+ + + 
Sbjct: 217 EGEATGRACQLTELAGSQLYVVHVSCAQAVEKIAEARNKGLNVWGETCPQYLVLDQSYLE 276

Query: 251 KLEKGEQKYV 222
           K      KYV
Sbjct: 277 KPNFEGAKYV 286


>UniRef50_UPI00015B49FE Cluster: PREDICTED: similar to
           alpha-glucosidase isozyme I; n=1; Nasonia
           vitripennis|Rep: PREDICTED: similar to alpha-glucosidase
           isozyme I - Nasonia vitripennis
          Length = 590

 Score = 35.1 bits (77), Expect = 2.2
 Identities = 16/49 (32%), Positives = 25/49 (51%)
 Frame = -2

Query: 338 IIKAAKERGVKVTCEVCPHHLFLNSNDITKLEKGEQKYVQYYVVLKTKQ 192
           + K AKE G+K+  ++ P+H            KG  KY QYY+  + K+
Sbjct: 105 LTKKAKELGIKIIMDLVPNHTSDKHQWFVDSLKGNTKYAQYYIWREGKE 153


>UniRef50_A6WFZ1 Cluster: Dihydropyrimidinase; n=1; Kineococcus
           radiotolerans SRS30216|Rep: Dihydropyrimidinase -
           Kineococcus radiotolerans SRS30216
          Length = 472

 Score = 35.1 bits (77), Expect = 2.2
 Identities = 18/59 (30%), Positives = 29/59 (49%), Gaps = 1/59 (1%)
 Frame = -2

Query: 431 EREKTAAVILMASLL-DRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSND 258
           E E     I +A +  D P+++ HV+    +  I +A+  G  V  E CP +L+L   D
Sbjct: 221 EGEAVNRAIALAEVAGDTPLYVVHVSSSPALDRIASARSEGRNVFAETCPQYLYLTLED 279


>UniRef50_A5GXS3 Cluster: Faciata 1-like protein; n=6; Poaceae|Rep:
           Faciata 1-like protein - Zea mays (Maize)
          Length = 348

 Score = 35.1 bits (77), Expect = 2.2
 Identities = 21/63 (33%), Positives = 33/63 (52%), Gaps = 5/63 (7%)
 Frame = -1

Query: 174 SIIDVFATDHAPHTVEEKNSENPPPGYPGL-----ETILPLLLNAVHQGRLTIEDLLCRI 10
           +++DV  TD +  TVEE N  NP  G PG      ET LP ++  +   R  I  ++  +
Sbjct: 187 AVVDVPLTDSSSATVEEINQPNPKDGSPGAASAIPETDLPEIVQVIRSCRDGIHKVVELL 246

Query: 9   RHE 1
           +H+
Sbjct: 247 QHK 249


>UniRef50_Q2LWS0 Cluster: DNA polymerase III, delta subunit; n=1;
           Syntrophus aciditrophicus SB|Rep: DNA polymerase III,
           delta subunit - Syntrophus aciditrophicus (strain SB)
          Length = 460

 Score = 34.7 bits (76), Expect = 2.9
 Identities = 26/85 (30%), Positives = 41/85 (48%)
 Frame = -1

Query: 255 YKIGKGRAKVCPVLCSPEDQAELWRNISIIDVFATDHAPHTVEEKNSENPPPGYPGLETI 76
           Y+I     K+   L SPEDQA    N+ ++D    D  P  + E  +   PP  PG   +
Sbjct: 36  YEISDAFTKIIDALLSPEDQA---LNLFVLD--GEDEDPERIGE--NLMTPPLLPG-RKV 87

Query: 75  LPLLLNAVHQGRLTIEDLLCRIRHE 1
           + +    +   R T++DL+ RIR +
Sbjct: 88  VAVRRTQLFSSRKTLKDLVKRIREQ 112


>UniRef50_A3PPE1 Cluster: Dihydropyrimidinase; n=3; Rhodobacter
           sphaeroides|Rep: Dihydropyrimidinase - Rhodobacter
           sphaeroides (strain ATCC 17029 / ATH 2.4.9)
          Length = 485

 Score = 34.7 bits (76), Expect = 2.9
 Identities = 19/71 (26%), Positives = 32/71 (45%)
 Frame = -2

Query: 434 AEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 255
           AE E     I +A L+   + I HV+  E   ++  A+  G+ +  E CP +L     D+
Sbjct: 217 AEAEAINRAISLARLVGAGLFIVHVSTPEGADLVARAQASGLPIHAETCPQYLAFTRADL 276

Query: 254 TKLEKGEQKYV 222
            +      KY+
Sbjct: 277 DRPGMEGAKYI 287


>UniRef50_Q7JZT9 Cluster: RE13129p; n=5; Diptera|Rep: RE13129p -
           Drosophila melanogaster (Fruit fly)
          Length = 492

 Score = 34.7 bits (76), Expect = 2.9
 Identities = 12/43 (27%), Positives = 26/43 (60%)
 Frame = -2

Query: 383 RPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 255
           R +HI + +  E + +++  + +G  +T + CPH+L L + D+
Sbjct: 255 RCIHILNCSSGESLPLVEECRRQGGNLTVDTCPHYLALAAEDV 297


>UniRef50_Q11EY4 Cluster: Dihydropyrimidinase; n=25;
           Proteobacteria|Rep: Dihydropyrimidinase - Mesorhizobium
           sp. (strain BNC1)
          Length = 485

 Score = 34.3 bits (75), Expect = 3.9
 Identities = 23/84 (27%), Positives = 43/84 (51%)
 Frame = -2

Query: 509 FLLEDMTIWQKHFQSWPKKMPVCTHAEREKTAAVILMASLLDRPVHICHVARKEEILIIK 330
           +L E M+  + H  S P ++      E E T   I++A     PV+I H + ++    I+
Sbjct: 193 YLQEGMSGPEAHAYSRPPEV------EGEATNRAIMIADAAGVPVYIVHTSCEQSHEAIR 246

Query: 329 AAKERGVKVTCEVCPHHLFLNSND 258
            A+++G++V  E    HL L+ ++
Sbjct: 247 RARQKGMRVYGEPLIQHLLLDESE 270



 Score = 34.3 bits (75), Expect = 3.9
 Identities = 27/76 (35%), Positives = 34/76 (44%), Gaps = 8/76 (10%)
 Frame = -1

Query: 237 RAKVCPVLCSPEDQAELWRNISI--IDVFATDHAPHTVEEK-----NSENPPPGYPGLET 79
           R  + P       Q  LW  ++   + V ATDHA  T E+K     +    P G  GLE 
Sbjct: 281 RRVMSPPFRDKRHQDSLWAGLAAGSLQVVATDHAAFTTEQKRLGLNDFTKIPNGTGGLED 340

Query: 78  ILPLLLN-AVHQGRLT 34
            +PLL    V  GRLT
Sbjct: 341 RMPLLWTYGVKTGRLT 356


>UniRef50_Q0BZU5 Cluster: Putative dihydroorotase; n=1; Hyphomonas
           neptunium ATCC 15444|Rep: Putative dihydroorotase -
           Hyphomonas neptunium (strain ATCC 15444)
          Length = 426

 Score = 34.3 bits (75), Expect = 3.9
 Identities = 21/55 (38%), Positives = 26/55 (47%), Gaps = 2/55 (3%)
 Frame = -1

Query: 168 IDVFATDHAPHTVEEKNSE--NPPPGYPGLETILPLLLNAVHQGRLTIEDLLCRI 10
           ID   + H P   EEK         G  GLET+L  LLN  H G LT+ + L  +
Sbjct: 302 IDAVVSAHDPQPPEEKRLPFGEAAFGAAGLETVLSALLNLHHDGPLTLLEALAPV 356


>UniRef50_A3UJX0 Cluster: Aspartate transcarbamoylase, pyrC'
           subunit; n=1; Oceanicaulis alexandrii HTCC2633|Rep:
           Aspartate transcarbamoylase, pyrC' subunit -
           Oceanicaulis alexandrii HTCC2633
          Length = 421

 Score = 34.3 bits (75), Expect = 3.9
 Identities = 25/77 (32%), Positives = 37/77 (48%), Gaps = 4/77 (5%)
 Frame = -1

Query: 237 RAKVCPVLCSPEDQAELWRNISI--IDVFATDHAPHTVEEKNSENPP--PGYPGLETILP 70
           R ++ P L S  D+  L   +S   ID   +DH   T E K    P   PG   LE +LP
Sbjct: 270 RYRLEPPLRSENDRQALIDALSDGRIDAVVSDHIALTNESKAHPFPEAAPGSATLEALLP 329

Query: 69  LLLNAVHQGRLTIEDLL 19
           +L     +GR+++ + L
Sbjct: 330 VLCGLAEEGRMSLAEAL 346


>UniRef50_UPI0001554813 Cluster: PREDICTED: hypothetical protein;
           n=1; Ornithorhynchus anatinus|Rep: PREDICTED:
           hypothetical protein - Ornithorhynchus anatinus
          Length = 554

 Score = 33.9 bits (74), Expect = 5.1
 Identities = 11/20 (55%), Positives = 16/20 (80%)
 Frame = -3

Query: 832 GNIVKLPGFIDVHVHVREPG 773
           G++V +PG +D HVH+ EPG
Sbjct: 76  GDLVVMPGVVDCHVHINEPG 95


>UniRef50_Q12EE5 Cluster: Allantoinase; n=57;
           Betaproteobacteria|Rep: Allantoinase - Polaromonas sp.
           (strain JS666 / ATCC BAA-500)
          Length = 446

 Score = 33.9 bits (74), Expect = 5.1
 Identities = 14/41 (34%), Positives = 23/41 (56%)
 Frame = -2

Query: 377 VHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 255
           VH+C ++    + ++  AK  G+ VTC+V  + L L   DI
Sbjct: 242 VHLCRISSAAGVALVGKAKAEGLDVTCDVSINSLHLTDVDI 282


>UniRef50_A3ZYR8 Cluster: Dihydroorotase; n=1; Blastopirellula
           marina DSM 3645|Rep: Dihydroorotase - Blastopirellula
           marina DSM 3645
          Length = 422

 Score = 33.9 bits (74), Expect = 5.1
 Identities = 26/84 (30%), Positives = 38/84 (45%), Gaps = 2/84 (2%)
 Frame = -3

Query: 832 GNIVKLPGFIDVHVHVREPGANIKGRF*DLLPQXHWLVV--LTMICAMPNTNPSIVDRTA 659
           G IV  PG ID+HV +REPG         +       +V   T I  +PNT P +    +
Sbjct: 49  GKIVA-PGLIDMHVQLREPGWEEDE---TIASGAAAAIVGGFTSIACIPNTEPPLDSPAS 104

Query: 658 FDYASTLARVSARCDYALYVGASS 587
            +Y    A  + +C+  +   ASS
Sbjct: 105 IEYVRHKAARADKCNVFVIACASS 128


>UniRef50_Q18IV3 Cluster: Dihydroorotase; n=1; Haloquadratum walsbyi
           DSM 16790|Rep: Dihydroorotase - Haloquadratum walsbyi
           (strain DSM 16790)
          Length = 474

 Score = 33.9 bits (74), Expect = 5.1
 Identities = 23/83 (27%), Positives = 43/83 (51%), Gaps = 12/83 (14%)
 Frame = -1

Query: 231 KVCPVLCSPEDQAELWRNI--SIIDVFATDHAPH--TVEEKNS-------ENPPPGYPGL 85
           K+ P L   + + +LW  +   +ID   TDH PH  + +EK+        E  P    G+
Sbjct: 293 KISPPLRGEQSRQKLWHGLRDGVIDYAGTDHCPHKKSFKEKDEGKFGDIWEAIPGDNNGI 352

Query: 84  ETILPLLLN-AVHQGRLTIEDLL 19
           E  LP++++  V++  +++E L+
Sbjct: 353 EYFLPVMMSEGVNKNNISMERLV 375


>UniRef50_Q8YF78 Cluster: D-HYDANTOINASE; n=41; Proteobacteria|Rep:
           D-HYDANTOINASE - Brucella melitensis
          Length = 489

 Score = 33.5 bits (73), Expect = 6.8
 Identities = 16/58 (27%), Positives = 33/58 (56%)
 Frame = -2

Query: 431 EREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSND 258
           E E T   I++A     P+++ HV+ ++    I+ A+++G++V  E    HL L+ ++
Sbjct: 218 EGEATNRAIMIADQAGVPLYVVHVSCEQSHEAIRRARQKGIRVFGEPLIQHLTLDESE 275


>UniRef50_P72934 Cluster: Probable dihydroorotase-like protein; n=1;
           Synechocystis sp. PCC 6803|Rep: Probable
           dihydroorotase-like protein - Synechocystis sp. (strain
           PCC 6803)
          Length = 441

 Score = 33.5 bits (73), Expect = 6.8
 Identities = 17/38 (44%), Positives = 19/38 (50%), Gaps = 2/38 (5%)
 Frame = -1

Query: 171 IIDVFATDHAPHTVEEKNS--ENPPPGYPGLETILPLL 64
           +ID  A DH   T EEK       PPG  G E +LP L
Sbjct: 329 VIDAIAVDHQAFTYEEKTQTFAETPPGAIGYELVLPCL 366


  Database: uniref50
    Posted date:  Oct 5, 2007 11:19 AM
  Number of letters in database: 575,637,011
  Number of sequences in database:  1,657,284
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 806,311,785
Number of Sequences: 1657284
Number of extensions: 15715575
Number of successful extensions: 39082
Number of sequences better than 10.0: 208
Number of HSP's better than 10.0 without gapping: 37282
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 38932
length of database: 575,637,011
effective HSP length: 100
effective length of database: 409,908,611
effective search space used: 73373641369
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

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