Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= pg--0064.Seq
(630 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_Q9UJ83 Cluster: 2-hydroxyacyl-CoA lyase 1; n=40; Eukary... 147 2e-34
UniRef50_Q17474 Cluster: Putative uncharacterized protein; n=3; ... 124 2e-27
UniRef50_A6MJX0 Cluster: 2-hydroxyacyl-CoA lyase 1-like protein;... 105 7e-22
UniRef50_Q9FNY6 Cluster: Oxalyl-CoA decarboxylase; n=13; Magnoli... 101 1e-20
UniRef50_A0CTV7 Cluster: Chromosome undetermined scaffold_27, wh... 101 1e-20
UniRef50_Q9Y7M1 Cluster: Oxalyl-CoA decarboxylase; n=5; Fungi/Me... 91 2e-17
UniRef50_Q75PZ0 Cluster: Oxalyl-CoA decarboxylase; n=1; Bifidoba... 83 5e-15
UniRef50_Q0TZB1 Cluster: Putative uncharacterized protein; n=1; ... 81 2e-14
UniRef50_A7TJH4 Cluster: Putative uncharacterized protein; n=1; ... 81 2e-14
UniRef50_Q54DA9 Cluster: Putative uncharacterized protein; n=1; ... 81 2e-14
UniRef50_Q757R7 Cluster: AEL055Cp; n=1; Eremothecium gossypii|Re... 81 3e-14
UniRef50_P39994 Cluster: Uncharacterized protein YEL020C; n=3; S... 72 1e-11
UniRef50_P40149 Cluster: Oxalyl-CoA decarboxylase; n=60; Bacteri... 56 9e-07
UniRef50_Q96F08 Cluster: IlvB (Bacterial acetolactate synthase)-... 54 3e-06
UniRef50_A0LEZ5 Cluster: Thiamine pyrophosphate enzyme TPP bindi... 52 2e-05
UniRef50_Q67QP4 Cluster: Acetolactate synthase-like TPP-requirin... 50 3e-05
UniRef50_A4VE07 Cluster: 2-hydroxyphytanoyl-CoA lyase, putative;... 47 4e-04
UniRef50_A7H9A1 Cluster: Thiamine pyrophosphate protein central ... 46 6e-04
UniRef50_UPI0000F347A9 Cluster: UPI0000F347A9 related cluster; n... 45 0.002
UniRef50_A3PYZ1 Cluster: Thiamine pyrophosphate enzyme TPP bindi... 44 0.002
UniRef50_Q6DDK5 Cluster: Ilvbl-prov protein; n=2; Bilateria|Rep:... 44 0.003
UniRef50_Q54YW0 Cluster: Putative uncharacterized protein; n=3; ... 44 0.003
UniRef50_A1SLX3 Cluster: Thiamine pyrophosphate enzyme domain pr... 44 0.004
UniRef50_Q1LF51 Cluster: Thiamine pyrophosphate enzyme-like TPP ... 43 0.005
UniRef50_Q8ELJ0 Cluster: Acetolactate synthase large subunit; n=... 41 0.021
UniRef50_Q6D0F1 Cluster: Acetolactate synthase isozyme I large s... 41 0.028
UniRef50_Q6AJI2 Cluster: Acetolactate synthase; n=42; cellular o... 40 0.037
UniRef50_Q2SEE0 Cluster: Thiamine pyrophosphate-requiring enzyme... 40 0.049
UniRef50_P66947 Cluster: Probable acetolactate synthase; n=12; M... 39 0.086
UniRef50_Q8U2A4 Cluster: Acetolactate synthase; n=4; cellular or... 38 0.20
UniRef50_Q93PS3 Cluster: Sulfoacetaldehyde acetyltransferase; n=... 36 0.61
UniRef50_Q2I6K8 Cluster: IlvB acetolactate synthase; n=1; uncult... 36 1.1
UniRef50_A0BW02 Cluster: Chromosome undetermined scaffold_130, w... 36 1.1
UniRef50_P08142 Cluster: Acetolactate synthase isozyme 1 large s... 36 1.1
UniRef50_Q88U88 Cluster: Pyruvate oxidase; n=5; Lactobacillaceae... 35 1.4
UniRef50_A1SHD8 Cluster: Thiamine pyrophosphate enzyme domain pr... 35 1.4
UniRef50_Q6N658 Cluster: Possible benzaldehyde lyase; n=2; Rhodo... 34 2.4
UniRef50_Q5CR51 Cluster: DHHC family palmitoyl transferase with ... 34 2.4
UniRef50_Q2NGE8 Cluster: Putative uncharacterized protein; n=1; ... 34 2.4
UniRef50_A3VG64 Cluster: Acetolactate synthase large subunit; n=... 34 3.2
UniRef50_UPI00006CDE0D Cluster: hypothetical protein TTHERM_0029... 33 4.3
UniRef50_A4A7Q3 Cluster: Acetolactate synthase large subunit; n=... 33 4.3
UniRef50_Q9CFJ5 Cluster: 1-deoxyxylulose-5-phosphate synthase; n... 33 5.7
UniRef50_Q3XZD0 Cluster: Pyruvate decarboxylase; n=3; Lactobacil... 33 5.7
UniRef50_A3VND4 Cluster: Sensor protein; n=1; Parvularcula bermu... 33 5.7
UniRef50_UPI0000499DA2 Cluster: conserved hypothetical protein; ... 33 7.5
UniRef50_A4ABB6 Cluster: Pyruvate decarboxylase; n=2; Proteobact... 33 7.5
UniRef50_A2ESQ8 Cluster: Surface antigen BspA-like; n=3; Trichom... 33 7.5
UniRef50_P37063 Cluster: Pyruvate oxidase; n=2; Lactobacillus pl... 33 7.5
UniRef50_UPI0000499EB4 Cluster: hypothetical protein 185.t00011;... 32 9.9
UniRef50_A3X9K6 Cluster: Acetolactate synthase-like TPP-requirin... 32 9.9
UniRef50_A3DID9 Cluster: Acetolactate synthase; n=3; Clostridium... 32 9.9
UniRef50_Q2U8M9 Cluster: Thiamine pyrophosphate-requiring enzyme... 32 9.9
>UniRef50_Q9UJ83 Cluster: 2-hydroxyacyl-CoA lyase 1; n=40;
Eukaryota|Rep: 2-hydroxyacyl-CoA lyase 1 - Homo sapiens
(Human)
Length = 578
Score = 147 bits (357), Expect = 2e-34
Identities = 81/197 (41%), Positives = 113/197 (57%)
Frame = +3
Query: 3 RMNWMLHFGQPPRYAPDVKIIQVEISPARISQQQEIRISSTLRH*TFYRSSCKKVVRKEV 182
R+NW+LHFG PPRY PDVK IQV+I + + ++ L + + + K
Sbjct: 282 RLNWILHFGLPPRYQPDVKFIQVDICAEELGNNVKPAVT-LLGNIHAVTKQLLEELDKTP 340
Query: 183 LIATSKQQLVAGTETETKSKHRICEAQASSTAVPLNYYTVFKTVQQGIPKDSIIVSEGAN 362
+ + + KS + AS ++P+NYYTVF VQ+ +P+D +VSEGAN
Sbjct: 341 WQYPPESKWWKTLREKMKSNEAASKELASKKSLPMNYYTVFYHVQEQLPRDCFVVSEGAN 400
Query: 363 TMDIGRGLLLNNHPRHRLDAGTFGTMGVGPGFAIAAAMWCRDYAPGKRVFVLKETLLLAS 542
TMDIGR +L N PRHRLDAGTFGTMGVG GFAIAAA+ +D +PG+ + ++
Sbjct: 401 TMDIGRTVLQNYLPRHRLDAGTFGTMGVGLGFAIAAAVVAKDRSPGQWIICVE-----GD 455
Query: 543 QAWX*RHVPVQVTCNYN 593
A+ + V+ C YN
Sbjct: 456 SAFGFSGMEVETICRYN 472
Score = 36.7 bits (81), Expect = 0.46
Identities = 16/66 (24%), Positives = 35/66 (53%)
Frame = +1
Query: 46 RPTLKLFRSKYLLQEFHNSKKSELAVHSDIRPFTEALVKRLSERKFSLQPQNNSWWQGLK 225
+P +K + +E N+ K + + +I T+ L++ L + + P++ WW+ L+
Sbjct: 296 QPDVKFIQVDICAEELGNNVKPAVTLLGNIHAVTKQLLEELDKTPWQYPPESK-WWKTLR 354
Query: 226 QKQKAN 243
+K K+N
Sbjct: 355 EKMKSN 360
>UniRef50_Q17474 Cluster: Putative uncharacterized protein; n=3;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 634
Score = 124 bits (298), Expect = 2e-27
Identities = 61/174 (35%), Positives = 95/174 (54%), Gaps = 1/174 (0%)
Frame = +3
Query: 3 RMNWMLHFGQPPRYAPDVKIIQVEISPARISQQQEIRISSTLRH*TFYRSSCKKVVRKEV 182
R NW+LHFG PPR+ DVK++Q++I P Q + + + + R
Sbjct: 341 RFNWILHFGLPPRFQKDVKVVQIDICPEEFHQNVKTEVPLLG---DIGETLAELTPRLGD 397
Query: 183 LIATSKQQLVAGTETETKSKHRICEAQASSTAVPLNYYTVFKTVQQGIPK-DSIIVSEGA 359
+ + E + PLNYY ++ +++ + D I+++EGA
Sbjct: 398 WTYDESTEWFKKLRENAEKNRAAVEKFVDDHSTPLNYYAAYQPIREFLANNDVIVINEGA 457
Query: 360 NTMDIGRGLLLNNHPRHRLDAGTFGTMGVGPGFAIAAAMWCRDYAPGKRVFVLK 521
NTMDIGR ++ + P+ RLDAGTFGTMGVG GF++AAA+W RD++P +V V++
Sbjct: 458 NTMDIGRTMMPSRLPKRRLDAGTFGTMGVGHGFSLAAALWARDHSPKTKVLVVQ 511
>UniRef50_A6MJX0 Cluster: 2-hydroxyacyl-CoA lyase 1-like protein;
n=2; Simiiformes|Rep: 2-hydroxyacyl-CoA lyase 1-like
protein - Callithrix jacchus (Common marmoset)
Length = 200
Score = 105 bits (253), Expect = 7e-22
Identities = 55/99 (55%), Positives = 67/99 (67%)
Frame = +3
Query: 297 TVFKTVQQGIPKDSIIVSEGANTMDIGRGLLLNNHPRHRLDAGTFGTMGVGPGFAIAAAM 476
TVF VQ+ +P+D +VSEGANTMDIGR +L N PRHRLDAGTFGTMGVG GFAIAAAM
Sbjct: 1 TVFYHVQEQLPRDCFVVSEGANTMDIGRTVLQNYLPRHRLDAGTFGTMGVGLGFAIAAAM 60
Query: 477 WCRDYAPGKRVFVLKETLLLASQAWX*RHVPVQVTCNYN 593
+D PG+RV ++ A+ + V+ C YN
Sbjct: 61 VAKDRHPGQRVICVE-----GDSAFGFSGMEVETICRYN 94
>UniRef50_Q9FNY6 Cluster: Oxalyl-CoA decarboxylase; n=13;
Magnoliophyta|Rep: Oxalyl-CoA decarboxylase -
Arabidopsis thaliana (Mouse-ear cress)
Length = 572
Score = 101 bits (243), Expect = 1e-20
Identities = 56/163 (34%), Positives = 85/163 (52%), Gaps = 5/163 (3%)
Frame = +3
Query: 3 RMNWMLHFGQPPRYAPDVKIIQVEISPARIS-QQQEIRISSTLRH*TFYRSSCKKVVRKE 179
R+NW+LHFG+ P++ DVK I V++S I ++ + I + + ++ +
Sbjct: 285 RLNWLLHFGESPKWDKDVKFILVDVSEEEIELRKPHLGIVGDAKT---VIGLLNREIKDD 341
Query: 180 VLIATSKQQLVAGTETETKSKHRICEAQASSTAVPLNYYTVFKTVQQGI----PKDSIIV 347
V + K E Q + VP N+ T + ++ I ++V
Sbjct: 342 PFCLGKSNSWVESISKKAKENGEKMEIQLAKDVVPFNFLTPMRIIRDAILAVEGPSPVVV 401
Query: 348 SEGANTMDIGRGLLLNNHPRHRLDAGTFGTMGVGPGFAIAAAM 476
SEGANTMD+GR +L+ PR RLDAGT+GTMGVG G+ IAAA+
Sbjct: 402 SEGANTMDVGRSVLVQKEPRTRLDAGTWGTMGVGLGYCIAAAV 444
>UniRef50_A0CTV7 Cluster: Chromosome undetermined scaffold_27, whole
genome shotgun sequence; n=1; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_27,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 552
Score = 101 bits (243), Expect = 1e-20
Identities = 58/173 (33%), Positives = 99/173 (57%), Gaps = 1/173 (0%)
Frame = +3
Query: 3 RMNWMLHFGQPPRYAPDVKIIQVEISPARISQQQEIRISSTLRH*TFYRSSCKKVVRKEV 182
R+NW+LHFG PPR+ + + IQ++ P + + R ++ + +K
Sbjct: 272 RLNWILHFGLPPRFDDNCQFIQIDNFPEEFNNNR--RTTTLFGDVSLVVDQLQKSFGNWQ 329
Query: 183 LIATSKQQLVAGTETETKSKHRICEAQA-SSTAVPLNYYTVFKTVQQGIPKDSIIVSEGA 359
++KQ + + ++K+ + Q + +PL YY+ F ++Q +P+D + V EGA
Sbjct: 330 F--SNKQWI--DKLFDKRNKNTLTNQQLMNDKELPLEYYSAFGIIKQYLPRDCVYVGEGA 385
Query: 360 NTMDIGRGLLLNNHPRHRLDAGTFGTMGVGPGFAIAAAMWCRDYAPGKRVFVL 518
NTMD+GR ++ ++ PR +LD+GTFGTMG+G FAIA+ + RD K+VF +
Sbjct: 386 NTMDVGRTIIEHDLPRRKLDSGTFGTMGIGLPFAIASKLVFRD----KQVFAI 434
>UniRef50_Q9Y7M1 Cluster: Oxalyl-CoA decarboxylase; n=5;
Fungi/Metazoa group|Rep: Oxalyl-CoA decarboxylase -
Schizosaccharomyces pombe (Fission yeast)
Length = 568
Score = 91.5 bits (217), Expect = 2e-17
Identities = 58/163 (35%), Positives = 87/163 (53%), Gaps = 6/163 (3%)
Frame = +3
Query: 3 RMNWMLHFGQPPRYAPDVKIIQVEISPARISQQQ-EIRISSTLRH*TFYRSSCKKVVRKE 179
R+NW+ +G PP+++P+ K IQ++ + + ++ ++ K V +
Sbjct: 271 RLNWIFQYGLPPKWSPNAKFIQIDTNAETLGNNAADLDLAIWADVGLTIDCLFKLVQTWK 330
Query: 180 VLIATSKQQLVAGTETETKSKHRICEAQASSTAVPLNY--YTVFKTVQQGIPKDS---II 344
+ S L ET +K++ + E++ SS + +NY Y V + +Q K
Sbjct: 331 YSVGISTPYLRTLNETRSKNEKKALESRKSSIPLQMNYALYVVNEELQSLSLKSKRNITW 390
Query: 345 VSEGANTMDIGRGLLLNNHPRHRLDAGTFGTMGVGPGFAIAAA 473
VSEGANTMD GR LL HPR RLDAGT TMGVG G+AIA+A
Sbjct: 391 VSEGANTMDRGRQLLEVTHPRGRLDAGTMSTMGVGMGYAIASA 433
>UniRef50_Q75PZ0 Cluster: Oxalyl-CoA decarboxylase; n=1;
Bifidobacterium animalis|Rep: Oxalyl-CoA decarboxylase -
Bifidobacterium animalis subsp. lactis (Bifidobacterium
lactis)
Length = 590
Score = 83.0 bits (196), Expect = 5e-15
Identities = 49/161 (30%), Positives = 82/161 (50%), Gaps = 3/161 (1%)
Frame = +3
Query: 3 RMNWMLHFGQPPRYAPDVKIIQVEISPARISQQQEIRISSTLRH*TFYRSSCKKV-VRKE 179
R+NWML+FG+ + P+VK IQ++I P I + I +S+ + + E
Sbjct: 288 RLNWMLNFGEGKEWNPNVKFIQIDIDPNEIENARSIACPVV----GDIKSAMQMINAGLE 343
Query: 180 VLIATSKQQLVAGTETETKSKHRICEAQASSTAVPLNYYTVFKTVQQGIP--KDSIIVSE 353
+ Q + + + + A+ +S VP+ +Y +++ KD I+ +E
Sbjct: 344 KTPVKASAQWLDMLKADAEKNDAKFAARVNSNTVPMGHYDALGAIKKVYDQHKDMILTNE 403
Query: 354 GANTMDIGRGLLLNNHPRHRLDAGTFGTMGVGPGFAIAAAM 476
GANT+D R ++ PRHRLD GT+G MG G++I AA+
Sbjct: 404 GANTLDDCRNIIDIYQPRHRLDCGTWGVMGCAVGYSIGAAV 444
>UniRef50_Q0TZB1 Cluster: Putative uncharacterized protein; n=1;
Phaeosphaeria nodorum|Rep: Putative uncharacterized
protein - Phaeosphaeria nodorum (Septoria nodorum)
Length = 478
Score = 81.4 bits (192), Expect = 2e-14
Identities = 51/164 (31%), Positives = 79/164 (48%), Gaps = 7/164 (4%)
Frame = +3
Query: 3 RMNWMLHFGQPPRYAPDVKIIQVEISPARISQQQEIRISSTLRH*TFYRSSCKKVVRKEV 182
R+NW+ H G+ P++ P+ K IQV+IS + E S L + +
Sbjct: 159 RLNWIFHHGEAPKWNPEAKFIQVDISAEETGRNSESAEHSLLGDVGVVATQLLTWLGDWT 218
Query: 183 LIATSKQQLVAGTETETKSKHRICEAQASSTAVPLNY---YTVFKTVQQGIPKDS----I 341
S + + + + K++ +I A ++PL Y + V KT + + S
Sbjct: 219 FDLNSSEYMAKIRQAKEKNE-KIASLTAQGPSMPLKYARAFDVMKTTLHNLSQPSEGRIC 277
Query: 342 IVSEGANTMDIGRGLLLNNHPRHRLDAGTFGTMGVGPGFAIAAA 473
++E NTMDI R + HPR RLDAGT+ TMG G +AIAA+
Sbjct: 278 YMAESTNTMDISRSIFPLEHPRLRLDAGTYATMGFGLPYAIAAS 321
>UniRef50_A7TJH4 Cluster: Putative uncharacterized protein; n=1;
Vanderwaltozyma polyspora DSM 70294|Rep: Putative
uncharacterized protein - Vanderwaltozyma polyspora DSM
70294
Length = 571
Score = 81.4 bits (192), Expect = 2e-14
Identities = 52/166 (31%), Positives = 89/166 (53%), Gaps = 8/166 (4%)
Frame = +3
Query: 3 RMNWMLHFGQPPRYAPDVKIIQVEISPARISQQQEIRISSTLRH*TFYRSSCK--KVVRK 176
++NW+LHFG ++ + IQ++ SP+ + + S L + F S K+ R
Sbjct: 279 KLNWILHFGSSSKWNENTLFIQIDNSPSNLG----LNNSKGLEYSLFGNISVTLDKLSRS 334
Query: 177 EVLIATSKQQLVAGTETETKSKHR-----ICEAQASSTAVPLNYYTVFKTVQQGI-PKDS 338
+ +KQ G K K + + + +++ + LNY V+ ++++ + +++
Sbjct: 335 LIKFNKNKQWRYQGPTENIKIKIKENEINLKKKESNHSTSQLNYNEVYGSLRKILNDRET 394
Query: 339 IIVSEGANTMDIGRGLLLNNHPRHRLDAGTFGTMGVGPGFAIAAAM 476
IIV EGANTMDI R ++P+HRLD G TMGVG G+AI+A +
Sbjct: 395 IIVMEGANTMDIARISFKTDYPQHRLDCGNLATMGVGLGYAISAKL 440
Score = 32.7 bits (71), Expect = 7.5
Identities = 13/20 (65%), Positives = 16/20 (80%)
Frame = +2
Query: 503 TCICVEGDSAFGFSGMVXET 562
T + ++GDSAFGFSGM ET
Sbjct: 446 TVVLIQGDSAFGFSGMEIET 465
>UniRef50_Q54DA9 Cluster: Putative uncharacterized protein; n=1;
Dictyostelium discoideum AX4|Rep: Putative
uncharacterized protein - Dictyostelium discoideum AX4
Length = 580
Score = 81.0 bits (191), Expect = 2e-14
Identities = 57/177 (32%), Positives = 92/177 (51%), Gaps = 21/177 (11%)
Frame = +3
Query: 3 RMNWMLHFGQPPRYAPDVKIIQVEISPARISQQQ------------EIRIS-STLRH*TF 143
R+NWM +FG+ P ++ DVK I V++ + S+ + + R+S + +R
Sbjct: 272 RLNWMFNFGKAPTFSTDVKFIIVDVDENQASKTKNPNVVPEIAIVGDARLSIAEMRKLFI 331
Query: 144 YRSSCKKVVRKEVLIATSKQQ------LVAGTETETKSKHRICEAQASSTAVPLNYYTVF 305
+ + ++ LI + K + L + +TKS + ++ L Y+ VF
Sbjct: 332 GETDEQPQPPQDSLIKSMKMEESWWSNLNQDIQVKTKSLATLMSEPQNNDQEYLTYHKVF 391
Query: 306 KTVQQG--IPKDSIIVSEGANTMDIGRGLLLNNHPRHRLDAGTFGTMGVGPGFAIAA 470
++ G +D+I V+EGANTMDIGR + PR RLDAGT TMGVG G+++AA
Sbjct: 392 NALRVGGLFQEDTIFVNEGANTMDIGRLCIPQTLPRSRLDAGTLATMGVGVGYSVAA 448
>UniRef50_Q757R7 Cluster: AEL055Cp; n=1; Eremothecium gossypii|Rep:
AEL055Cp - Ashbya gossypii (Yeast) (Eremothecium
gossypii)
Length = 545
Score = 80.6 bits (190), Expect = 3e-14
Identities = 48/160 (30%), Positives = 83/160 (51%), Gaps = 2/160 (1%)
Frame = +3
Query: 3 RMNWMLHFGQPPRYAPDVKIIQVEISPARISQQQEIRIS-STLRH*TFYRSSCKKVVRKE 179
R+NW+LH+G P++ D IQV+ PA + ++ S L + ++ V+ +
Sbjct: 264 RLNWILHYGSAPKWNADATFIQVDRDPATLGHNNSSGVNYSVLSDVELFINAITAVLPQS 323
Query: 180 VLIATSKQQLVAGTETETKSKHRICEAQASSTAVPLNYYTVFKTVQQGIP-KDSIIVSEG 356
+++ R + S PLNY+ V+ +++ I K++I+ +EG
Sbjct: 324 WQYRGVDNEVLDKIRENGVKLQRKAQLTPGS---PLNYHAVYSLLRKLIDDKNTILSAEG 380
Query: 357 ANTMDIGRGLLLNNHPRHRLDAGTFGTMGVGPGFAIAAAM 476
ANTMD R ++P+ RLDAGT TMG+G G+A++A +
Sbjct: 381 ANTMDNSRLWFGTDYPKRRLDAGTGATMGLGVGYALSAKL 420
>UniRef50_P39994 Cluster: Uncharacterized protein YEL020C; n=3;
Saccharomycetales|Rep: Uncharacterized protein YEL020C -
Saccharomyces cerevisiae (Baker's yeast)
Length = 560
Score = 71.7 bits (168), Expect = 1e-11
Identities = 51/160 (31%), Positives = 80/160 (50%), Gaps = 5/160 (3%)
Frame = +3
Query: 3 RMNWMLHFGQPPRYAPDVKIIQVEISPARISQQQEIRISSTLRH*TFYRSSCKKVVRKEV 182
R+NW+LHFG P++ + IQ + +P + + + L S +V E
Sbjct: 274 RLNWILHFGTSPKWNSESIFIQFDSNPETLGDNN-VSPGADLSIWGDIGLSVTALV--EE 330
Query: 183 LIATSKQQLVAGTETETKSKHRICEAQA----SSTAVPLNYYTVFKTVQQGIPK-DSIIV 347
L +G + E + K ++ + + + LNY V+ T++ I +I+V
Sbjct: 331 LTRQDSCWKYSGVKQEIREKIQLNQTRLLRKEKTRGAQLNYNQVYGTLRPLIDDYRTILV 390
Query: 348 SEGANTMDIGRGLLLNNHPRHRLDAGTFGTMGVGPGFAIA 467
+EGANTMDI R + PR RLDAGT TMG+G G+A+A
Sbjct: 391 TEGANTMDIARISFPTDAPRRRLDAGTNATMGIGLGYALA 430
>UniRef50_P40149 Cluster: Oxalyl-CoA decarboxylase; n=60;
Bacteria|Rep: Oxalyl-CoA decarboxylase - Oxalobacter
formigenes
Length = 568
Score = 55.6 bits (128), Expect = 9e-07
Identities = 41/163 (25%), Positives = 76/163 (46%), Gaps = 6/163 (3%)
Frame = +3
Query: 3 RMNWMLHFGQPPRYAPDVK-IIQVEISPARISQQQEIR---ISSTLRH*TFYRSSCKKVV 170
R+NW++ G+ + ++K +Q++I + Q I + + R + K
Sbjct: 282 RLNWLMQHGKGKTWGDELKKYVQIDIQANEMDSNQPIAAPVVGDIKSAVSLLRKALKGAP 341
Query: 171 RKEVLIATSKQQLVAGTETETKSKHRICEAQASSTAVPLNYYTVFKTVQQGI--PKDSII 344
+ + + + V G + + K A + + +NY V+ + D +
Sbjct: 342 KADAEWTGALKAKVDGNKAKLAGK-----MTAETPSGMMNYSNSLGVVRDFMLANPDISL 396
Query: 345 VSEGANTMDIGRGLLLNNHPRHRLDAGTFGTMGVGPGFAIAAA 473
V+EGAN +D R ++ PR RLD+GT+G MG+G G+ +AAA
Sbjct: 397 VNEGANALDNTRMIVDMLKPRKRLDSGTWGVMGIGMGYCVAAA 439
Score = 33.5 bits (73), Expect = 4.3
Identities = 15/18 (83%), Positives = 15/18 (83%)
Frame = +2
Query: 509 ICVEGDSAFGFSGMVXET 562
I VEGDSAFGFSGM ET
Sbjct: 447 IAVEGDSAFGFSGMELET 464
>UniRef50_Q96F08 Cluster: IlvB (Bacterial acetolactate
synthase)-like; n=36; cellular organisms|Rep: IlvB
(Bacterial acetolactate synthase)-like - Homo sapiens
(Human)
Length = 632
Score = 54.0 bits (124), Expect = 3e-06
Identities = 30/88 (34%), Positives = 46/88 (52%)
Frame = +3
Query: 222 ETETKSKHRICEAQASSTAVPLNYYTVFKTVQQGIPKDSIIVSEGANTMDIGRGLLLNNH 401
E + + + E A A LN V + V++ +P +SI+V +G + + L+
Sbjct: 424 EADRQKEQTFREKAAMPVAQHLNPVQVLQLVEETLPDNSILVVDGGDFVGTAAHLVQPRG 483
Query: 402 PRHRLDAGTFGTMGVGPGFAIAAAMWCR 485
P LD G FGT+GVG GFA+ A + CR
Sbjct: 484 PLRWLDPGAFGTLGVGAGFALGAKL-CR 510
>UniRef50_A0LEZ5 Cluster: Thiamine pyrophosphate enzyme TPP binding
domain protein; n=1; Syntrophobacter fumaroxidans
MPOB|Rep: Thiamine pyrophosphate enzyme TPP binding
domain protein - Syntrophobacter fumaroxidans (strain
DSM 10017 / MPOB)
Length = 568
Score = 51.6 bits (118), Expect = 2e-05
Identities = 44/157 (28%), Positives = 73/157 (46%), Gaps = 3/157 (1%)
Frame = +3
Query: 27 GQPPRYAPDVKIIQVEISPARISQQQEIRISSTLRH*TFYRSSCKKVVRKEVLIATSKQQ 206
G R A KIIQV++ A + +++ ++ F + V A ++
Sbjct: 298 GYGSRIAEGAKIIQVDLDYAELCHNRDVEVAIQADAGAFLEE-----LEGAVSPAGGTRK 352
Query: 207 LVAGTET-ETKSKHRICEAQASSTAVPLNYYTVFKTVQQGIPKDSIIVSEGANTMDIGRG 383
+ T ET+ R SS AVP++ + + + + DSI++++G +T+ +
Sbjct: 353 WLDELRTMETELLERESRF-LSSDAVPIHPLRLAREIDAFLRDDSILIADGGDTVTMSAS 411
Query: 384 LLLNNHPRHRLDAGTFGTMGVGPGFAIA--AAMWCRD 488
++ P LD G GT+GVG FAIA AAM RD
Sbjct: 412 VIRPRGPGQWLDPGPLGTLGVGTPFAIAAKAAMPARD 448
>UniRef50_Q67QP4 Cluster: Acetolactate synthase-like TPP-requiring
enzyme; n=1; Symbiobacterium thermophilum|Rep:
Acetolactate synthase-like TPP-requiring enzyme -
Symbiobacterium thermophilum
Length = 551
Score = 50.4 bits (115), Expect = 3e-05
Identities = 31/158 (19%), Positives = 76/158 (48%), Gaps = 1/158 (0%)
Frame = +3
Query: 6 MNWMLHFGQPPRYAPDVKIIQVEISPARISQQQEIRISSTLRH*TFYRSSCKKVVRKEVL 185
+++ L +G P + ++IQV++ PA + ++ ++ T +
Sbjct: 275 LDFRLGYGGSPVWNEQCRLIQVDLDPAEPGRNRDAAVAIPGDSGTVMMQLL--ALGDLGA 332
Query: 186 IATSKQQLVAGTETETKSKHRICEAQASSTAVPLNYYTVFKTVQQGIPKDSIIVSEGANT 365
+++ + E E + + + +S A+P+N + + + +P+D+I++ +G +
Sbjct: 333 GRPARRAWLERLEAEEEKRLARMQPDLTSEAMPVNPLRLCAEIDRALPEDAILIGDGGDF 392
Query: 366 MDIGRGLL-LNNHPRHRLDAGTFGTMGVGPGFAIAAAM 476
+ ++ + +P +D G GT+G+G GFA+AA +
Sbjct: 393 VATAANVVRVRRYPAGWMDPGPLGTLGIGMGFAMAARL 430
>UniRef50_A4VE07 Cluster: 2-hydroxyphytanoyl-CoA lyase, putative;
n=1; Tetrahymena thermophila SB210|Rep:
2-hydroxyphytanoyl-CoA lyase, putative - Tetrahymena
thermophila SB210
Length = 405
Score = 46.8 bits (106), Expect = 4e-04
Identities = 17/27 (62%), Positives = 23/27 (85%)
Frame = +3
Query: 3 RMNWMLHFGQPPRYAPDVKIIQVEISP 83
R+NW+LHFG+PPR+ +VKII +EI P
Sbjct: 269 RLNWILHFGEPPRFNKNVKIIHIEICP 295
>UniRef50_A7H9A1 Cluster: Thiamine pyrophosphate protein central
region; n=1; Anaeromyxobacter sp. Fw109-5|Rep: Thiamine
pyrophosphate protein central region - Anaeromyxobacter
sp. Fw109-5
Length = 550
Score = 46.4 bits (105), Expect = 6e-04
Identities = 38/161 (23%), Positives = 72/161 (44%), Gaps = 4/161 (2%)
Frame = +3
Query: 6 MNWMLHFGQPPRYAPDVKIIQVEISPARISQQQEIRISSTLRH*TFYRSSCKKVVRKEVL 185
+++ + +G P +AP +++QV++ A I + + I + RS +++ L
Sbjct: 273 LDFRVGYGTEPTFAPGARVVQVDVDGAEIGRNRPIDVGIV----GDARSVLEQLEAGARL 328
Query: 186 IATSK--QQLVAGTETETKSKHRICEAQASSTAVPLNYYTVFKTVQQGIPK--DSIIVSE 353
++ + + ET K R E S P++++ + K + + D V +
Sbjct: 329 APAAEAWRAFLRQQETSRAEKQRGYE---ESDQRPIHHFRLAKALDTVASRAGDVTFVGD 385
Query: 354 GANTMDIGRGLLLNNHPRHRLDAGTFGTMGVGPGFAIAAAM 476
G N + + +L P LD G G +GVG FAIAA +
Sbjct: 386 GGNVVAVAAKVLKVKKPGRWLDPGPLGCLGVGAPFAIAAKL 426
>UniRef50_UPI0000F347A9 Cluster: UPI0000F347A9 related cluster; n=1;
Bos taurus|Rep: UPI0000F347A9 UniRef100 entry - Bos
Taurus
Length = 442
Score = 44.8 bits (101), Expect = 0.002
Identities = 28/88 (31%), Positives = 43/88 (48%)
Frame = +3
Query: 222 ETETKSKHRICEAQASSTAVPLNYYTVFKTVQQGIPKDSIIVSEGANTMDIGRGLLLNNH 401
+ + + + E A LN V + V+ +P + I+V +G N + L+
Sbjct: 319 QADQQKEQTFREKALMPVAQHLNPVRVLQLVEDTLPDNPILV-DGGNFVGTAAYLVQPRG 377
Query: 402 PRHRLDAGTFGTMGVGPGFAIAAAMWCR 485
P LD G FGT+GVG GFA+ A + CR
Sbjct: 378 PLCWLDPGAFGTLGVGAGFALGAKL-CR 404
>UniRef50_A3PYZ1 Cluster: Thiamine pyrophosphate enzyme TPP binding
domain protein; n=3; Mycobacterium|Rep: Thiamine
pyrophosphate enzyme TPP binding domain protein -
Mycobacterium sp. (strain JLS)
Length = 588
Score = 44.4 bits (100), Expect = 0.002
Identities = 37/154 (24%), Positives = 63/154 (40%), Gaps = 4/154 (2%)
Frame = +3
Query: 48 PDVKIIQVEISPARISQQQEIRISSTLRH*TFYRSSCKKVVRKEVLIATSKQ----QLVA 215
P +I+QV++ A I + Q++ ++ + C++ +R A +
Sbjct: 309 PGARIVQVDLDAAEIGRMQDVAVAIV--------ADCRETLRALQAAAADRDWPDWSEWV 360
Query: 216 GTETETKSKHRICEAQASSTAVPLNYYTVFKTVQQGIPKDSIIVSEGANTMDIGRGLLLN 395
T + + HR A++ + ++ Y + V + P + V +GA
Sbjct: 361 HTAVQAQRFHRALYPDAATPSGRMHPYFAARAVVEACPPGTTFVLDGAEAPAWAEFFATT 420
Query: 396 NHPRHRLDAGTFGTMGVGPGFAIAAAMWCRDYAP 497
L G GT+GVGPGFAI AA R AP
Sbjct: 421 ETVGGVLRLGYLGTLGVGPGFAIGAAR-ARPAAP 453
>UniRef50_Q6DDK5 Cluster: Ilvbl-prov protein; n=2; Bilateria|Rep:
Ilvbl-prov protein - Xenopus laevis (African clawed
frog)
Length = 649
Score = 44.0 bits (99), Expect = 0.003
Identities = 32/96 (33%), Positives = 48/96 (50%), Gaps = 5/96 (5%)
Frame = +3
Query: 222 ETETKSKHRICEAQASSTAVP---LNYYTVFKTVQQG--IPKDSIIVSEGANTMDIGRGL 386
E + HR E + SS P +N +V ++ ++SIIV++G + + +
Sbjct: 423 ELLAREHHRDEEIRQSSLTQPAERINPLSVLWQLEHNGLTDQESIIVADGGDFVGSAAYI 482
Query: 387 LLNNHPRHRLDAGTFGTMGVGPGFAIAAAMWCRDYA 494
L P LD G FGT+GVG GFA+ A + CR A
Sbjct: 483 LRPRGPLSWLDPGPFGTLGVGGGFALGAKL-CRPQA 517
>UniRef50_Q54YW0 Cluster: Putative uncharacterized protein; n=3;
Eukaryota|Rep: Putative uncharacterized protein -
Dictyostelium discoideum AX4
Length = 904
Score = 44.0 bits (99), Expect = 0.003
Identities = 23/67 (34%), Positives = 37/67 (55%)
Frame = +3
Query: 285 LNYYTVFKTVQQGIPKDSIIVSEGANTMDIGRGLLLNNHPRHRLDAGTFGTMGVGPGFAI 464
LN + + +P +I+V++G + + ++ P LD G FGT+GVG GF+I
Sbjct: 718 LNPLKALQMFDEQLPHKTIMVADGGDFVGSASYIVRPRAPLSWLDPGVFGTLGVGAGFSI 777
Query: 465 AAAMWCR 485
AA + CR
Sbjct: 778 AAKL-CR 783
>UniRef50_A1SLX3 Cluster: Thiamine pyrophosphate enzyme domain
protein TPP-binding; n=2; Bacteria|Rep: Thiamine
pyrophosphate enzyme domain protein TPP-binding -
Nocardioides sp. (strain BAA-499 / JS614)
Length = 588
Score = 43.6 bits (98), Expect = 0.004
Identities = 43/168 (25%), Positives = 75/168 (44%), Gaps = 3/168 (1%)
Frame = +3
Query: 24 FGQPPRYAPDV--KIIQVEISPARISQQQEIRISSTLRH*TFYRSSCKKVVRKEVL-IAT 194
+G+ P +AP + IQV++ R+ + + ++ R+ V R+ V +A
Sbjct: 289 WGKAPNWAPPALQRTIQVDVDDERLGVNKPVSLAILADAREALRALADAVERRTVPGLAA 348
Query: 195 SKQQLVAGTETETKSKHRICEAQASSTAVPLNYYTVFKTVQQGIPKDSIIVSEGANTMDI 374
+ +L + ++ A+A P++ V QQ +P D++ V +G NT+
Sbjct: 349 RRDRLEVWRGKVADERAKL--AKAVKPGSPVHPGHVPSVAQQVMPDDTVWVFDGGNTVVW 406
Query: 375 GRGLLLNNHPRHRLDAGTFGTMGVGPGFAIAAAMWCRDYAPGKRVFVL 518
+ PR L FG +G G G A+ AA+ AP +RV VL
Sbjct: 407 SNFHHSADVPRTILSTYKFGMLGAGMGQALGAAV----AAPDQRVCVL 450
>UniRef50_Q1LF51 Cluster: Thiamine pyrophosphate enzyme-like TPP
binding region; n=3; Bacteria|Rep: Thiamine
pyrophosphate enzyme-like TPP binding region - Ralstonia
metallidurans (strain CH34 / ATCC 43123 / DSM 2839)
Length = 640
Score = 43.2 bits (97), Expect = 0.005
Identities = 27/97 (27%), Positives = 46/97 (47%)
Frame = +3
Query: 219 TETETKSKHRICEAQASSTAVPLNYYTVFKTVQQGIPKDSIIVSEGANTMDIGRGLLLNN 398
TE E + ++ S P++ Y V + + + ++I + +G + + I +
Sbjct: 426 TEAEAVATEKLMPLFKSENK-PIHPYRVAYELNEFLADNTIYIGDGGDVVTISAQAVRPR 484
Query: 399 HPRHRLDAGTFGTMGVGPGFAIAAAMWCRDYAPGKRV 509
P +D G G++GVG GFAIAA + PGK V
Sbjct: 485 RPGQWMDPGALGSLGVGTGFAIAAGV----ANPGKEV 517
>UniRef50_Q8ELJ0 Cluster: Acetolactate synthase large subunit; n=4;
Bacteria|Rep: Acetolactate synthase large subunit -
Oceanobacillus iheyensis
Length = 586
Score = 41.1 bits (92), Expect = 0.021
Identities = 40/151 (26%), Positives = 71/151 (47%), Gaps = 4/151 (2%)
Frame = +3
Query: 48 PDVKIIQVEISPARISQQQ--EIRISSTLRH-*TFYRSSCKKVVRKEVLIATSKQQLVAG 218
PD K+IQ++I P I + EI + + L+ T K++ V + K+++
Sbjct: 303 PDTKLIQIDIDPNEIGRNYPVEIGVVADLKEALTVLNRVAKEIAPDGVSNSKIKEEIKNY 362
Query: 219 TETETKSKHRICEAQASSTAVPLNYYTVFKTVQQGIPKDSIIVSE-GANTMDIGRGLLLN 395
+ T+S EA + S + PL+ + V+ IP+D+ I ++ G N +G+ +
Sbjct: 363 RKEFTQSN---LEA-SESNSYPLSPQRILADVRSVIPRDAYITTDVGWNKNGVGQQFPI- 417
Query: 396 NHPRHRLDAGTFGTMGVGPGFAIAAAMWCRD 488
P L G + TMG G A+ A + +D
Sbjct: 418 YEPGSILTPGGYATMGFGAPAAMGAKIAKKD 448
>UniRef50_Q6D0F1 Cluster: Acetolactate synthase isozyme I large
subunit; n=5; Bacteria|Rep: Acetolactate synthase
isozyme I large subunit - Erwinia carotovora subsp.
atroseptica (Pectobacterium atrosepticum)
Length = 554
Score = 40.7 bits (91), Expect = 0.028
Identities = 24/66 (36%), Positives = 37/66 (56%), Gaps = 1/66 (1%)
Frame = +3
Query: 282 PLNYYTVFKTVQQGIPKDSIIVSE-GANTMDIGRGLLLNNHPRHRLDAGTFGTMGVGPGF 458
PL++Y + + Q + D+II ++ G + M + + L PR L +G FGTMG G
Sbjct: 359 PLSHYGLVQATAQALTDDAIITTDVGQHQMWVAQSYPLRR-PRQWLTSGGFGTMGFGLPA 417
Query: 459 AIAAAM 476
AI AA+
Sbjct: 418 AIGAAL 423
>UniRef50_Q6AJI2 Cluster: Acetolactate synthase; n=42; cellular
organisms|Rep: Acetolactate synthase - Desulfotalea
psychrophila
Length = 612
Score = 40.3 bits (90), Expect = 0.037
Identities = 40/154 (25%), Positives = 66/154 (42%), Gaps = 4/154 (2%)
Frame = +3
Query: 27 GQPPRYAPDVKIIQVEISPARISQQQEIRI---SSTLRH*TFYRSSCKKVVRKEVLIATS 197
G+ +A KII V+I P IS+ ++ + + L T +K +E+
Sbjct: 332 GKLEDFASKAKIIHVDIDPTSISKNVKVDVPIVADCLAALTAINDWLEKCPEEEIAERRD 391
Query: 198 KQQLVAGTETETKSKHRICEAQASSTAVPLNYYTVFKTVQQGIPKDSIIVSE-GANTMDI 374
+ T +H + + +S + V +T+ + ++II +E G N M
Sbjct: 392 AHKPWIDTVHNWTKEHPM---RYNSNGSEIKPQFVVETIDRLTKGEAIITTEVGQNQMWA 448
Query: 375 GRGLLLNNHPRHRLDAGTFGTMGVGPGFAIAAAM 476
+ N HPRH + +G GTMG G AI A M
Sbjct: 449 AQFYKFN-HPRHFVTSGGLGTMGFGLPAAIGAQM 481
>UniRef50_Q2SEE0 Cluster: Thiamine pyrophosphate-requiring enzyme;
n=3; Proteobacteria|Rep: Thiamine
pyrophosphate-requiring enzyme - Hahella chejuensis
(strain KCTC 2396)
Length = 591
Score = 39.9 bits (89), Expect = 0.049
Identities = 21/80 (26%), Positives = 37/80 (46%)
Frame = +3
Query: 234 KSKHRICEAQASSTAVPLNYYTVFKTVQQGIPKDSIIVSEGANTMDIGRGLLLNNHPRHR 413
+ + + QA + +N + + + + S I+++G + + L P
Sbjct: 389 RQREKDIRTQALTEGGRINPLDLLLQIDTALDEKSAIIADGGDFVATAAYTLRPRSPLSW 448
Query: 414 LDAGTFGTMGVGPGFAIAAA 473
LD G FGT+GVG GF + AA
Sbjct: 449 LDPGVFGTLGVGGGFVLGAA 468
>UniRef50_P66947 Cluster: Probable acetolactate synthase; n=12;
Mycobacterium|Rep: Probable acetolactate synthase -
Mycobacterium bovis
Length = 547
Score = 39.1 bits (87), Expect = 0.086
Identities = 19/74 (25%), Positives = 40/74 (54%)
Frame = +3
Query: 255 EAQASSTAVPLNYYTVFKTVQQGIPKDSIIVSEGANTMDIGRGLLLNNHPRHRLDAGTFG 434
+A+ +PL+ V+ + + +D+++V + + ++ + P LD+G FG
Sbjct: 353 KAELVDDRIPLHPMRVYAELAALLERDALVVIDAGDFGSYAGRMIDSYLPGCWLDSGPFG 412
Query: 435 TMGVGPGFAIAAAM 476
+G GPG+A+AA +
Sbjct: 413 CLGSGPGYALAAKL 426
>UniRef50_Q8U2A4 Cluster: Acetolactate synthase; n=4; cellular
organisms|Rep: Acetolactate synthase - Pyrococcus
furiosus
Length = 564
Score = 37.9 bits (84), Expect = 0.20
Identities = 35/144 (24%), Positives = 63/144 (43%), Gaps = 1/144 (0%)
Frame = +3
Query: 42 YAPDVKIIQVEISPARISQQQEIRISSTLRH*TFYRSSCKKVVRKEVLIATSKQQLVAGT 221
+AP+ KII ++I P + + ++ + R+ ++VR+ K++
Sbjct: 293 FAPEAKIIHIDIDPKEVGKNVKVDLGIIGDAKRVLRAIYNEIVRR-----AKKRESWPWL 347
Query: 222 ETETKSKHRICEAQASSTAVPLNYYTVFKTVQQGIPKDSIIVSE-GANTMDIGRGLLLNN 398
E + K + E L + K +++ +P D+I+ +E G N M + +
Sbjct: 348 EKVREFKEKYKEELVPIDGDYLRPPEILKELRKLLPPDAIVATEVGQNQMWVALFFPILK 407
Query: 399 HPRHRLDAGTFGTMGVGPGFAIAA 470
PR L +G GTMG G AI A
Sbjct: 408 -PRTFLTSGGLGTMGFGFPAAIGA 430
>UniRef50_Q93PS3 Cluster: Sulfoacetaldehyde acetyltransferase; n=5;
Peptococcaceae|Rep: Sulfoacetaldehyde acetyltransferase
- Desulfonispora thiosulfatigenes
Length = 584
Score = 36.3 bits (80), Expect = 0.61
Identities = 30/146 (20%), Positives = 62/146 (42%), Gaps = 1/146 (0%)
Frame = +3
Query: 42 YAPD-VKIIQVEISPARISQQQEIRISSTLRH*TFYRSSCKKVVRKEVLIATSKQQLVAG 218
Y P+ KIIQ+E++P +I ++ + + + + K+++ + + + ++L A
Sbjct: 294 YFPENAKIIQIEVNPKQIGRRHPVTVP-IIGDAKLATAELIKLLKAKGDVKPNAERL-AK 351
Query: 219 TETETKSKHRICEAQASSTAVPLNYYTVFKTVQQGIPKDSIIVSEGANTMDIGRGLLLNN 398
+ + E A P+N V V + +P+D+I+ ++ N
Sbjct: 352 IQERRNDWFKEIEEMAMMPGNPINPRRVLFEVAKLMPEDAILTTDIGNVASTANSYFKFT 411
Query: 399 HPRHRLDAGTFGTMGVGPGFAIAAAM 476
P+ + A TFG G + A M
Sbjct: 412 KPKKHIAALTFGNTGFAYQAGLGAQM 437
>UniRef50_Q2I6K8 Cluster: IlvB acetolactate synthase; n=1;
uncultured delta proteobacterium DeepAnt-32C6|Rep: IlvB
acetolactate synthase - uncultured delta proteobacterium
DeepAnt-32C6
Length = 680
Score = 35.5 bits (78), Expect = 1.1
Identities = 26/85 (30%), Positives = 44/85 (51%), Gaps = 1/85 (1%)
Frame = +3
Query: 225 TETKSKHRICEAQASSTAVPLNYYTVFKTVQQGIPKDSIIVSE-GANTMDIGRGLLLNNH 401
T+ +++ E + S AVPL +QQ +P D+I+ S+ G + + + L +
Sbjct: 469 TQESTRYLNAELRVSD-AVPLTPQRWRADLQQVLPADAIVFSDIGGHMLFNIQHLCIGRE 527
Query: 402 PRHRLDAGTFGTMGVGPGFAIAAAM 476
R L+ G FG+MG G A+ AA+
Sbjct: 528 QRFMLNLG-FGSMGHGTSAAVGAAL 551
>UniRef50_A0BW02 Cluster: Chromosome undetermined scaffold_130,
whole genome shotgun sequence; n=1; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_130,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 298
Score = 35.5 bits (78), Expect = 1.1
Identities = 20/62 (32%), Positives = 32/62 (51%)
Frame = +1
Query: 88 EFHNSKKSELAVHSDIRPFTEALVKRLSERKFSLQPQNNSWWQGLKQKQKANTEFVRLKQ 267
EF N K ++ +++RPF E L++R + LQ ++ Q QK E +LK+
Sbjct: 34 EFQNKKSADHLDPNELRPFLEDLMRRYDKMALELQAAQAKNYEYNDQNQKLIRENDQLKE 93
Query: 268 AA 273
AA
Sbjct: 94 AA 95
>UniRef50_P08142 Cluster: Acetolactate synthase isozyme 1 large
subunit; n=49; Bacteria|Rep: Acetolactate synthase
isozyme 1 large subunit - Escherichia coli (strain K12)
Length = 562
Score = 35.5 bits (78), Expect = 1.1
Identities = 23/66 (34%), Positives = 35/66 (53%), Gaps = 1/66 (1%)
Frame = +3
Query: 282 PLNYYTVFKTVQQGIPKDSIIVSE-GANTMDIGRGLLLNNHPRHRLDAGTFGTMGVGPGF 458
PL++Y + V + ++II ++ G + M + LN PR L +G GTMG G
Sbjct: 367 PLSHYGLINAVAACVDDNAIITTDVGQHQMWTAQAYPLNR-PRQWLTSGGLGTMGFGLPA 425
Query: 459 AIAAAM 476
AI AA+
Sbjct: 426 AIGAAL 431
>UniRef50_Q88U88 Cluster: Pyruvate oxidase; n=5;
Lactobacillaceae|Rep: Pyruvate oxidase - Lactobacillus
plantarum
Length = 585
Score = 35.1 bits (77), Expect = 1.4
Identities = 31/146 (21%), Positives = 61/146 (41%), Gaps = 4/146 (2%)
Frame = +3
Query: 51 DVKIIQVEISPARISQQQEIRISSTLRH*TFYRSSCKKVVRKEVLIA--TSKQQLVAGTE 224
D K +Q+E+ P + + + K +++ + ++ S +
Sbjct: 292 DFKYVQIELDPGKFGRHHHLDFG--------VNGDAKVFIKRALALSEPASPSPYYQAAK 343
Query: 225 TETKSKHRICEAQASSTAVPLNYYTVFKTVQQGIPKDSIIVSE-GANTMDIGRGLLLNNH 401
+ + + + T PL Y V++ + + D++ + G NT++ R L +N
Sbjct: 344 ADMADWKQYLKKLSERTTDPLEYEQVYQEINRVAADDAVFSMDVGDNTINSFRFLKMN-- 401
Query: 402 PRHRL-DAGTFGTMGVGPGFAIAAAM 476
P+ +L + F TMG G AIAA M
Sbjct: 402 PKQKLLTSALFATMGAGVPGAIAAKM 427
>UniRef50_A1SHD8 Cluster: Thiamine pyrophosphate enzyme domain
protein TPP-binding; n=4; Actinomycetales|Rep: Thiamine
pyrophosphate enzyme domain protein TPP-binding -
Nocardioides sp. (strain BAA-499 / JS614)
Length = 551
Score = 35.1 bits (77), Expect = 1.4
Identities = 17/73 (23%), Positives = 36/73 (49%)
Frame = +3
Query: 258 AQASSTAVPLNYYTVFKTVQQGIPKDSIIVSEGANTMDIGRGLLLNNHPRHRLDAGTFGT 437
A + A P++ ++ + + +D++++ +G + + + P LD G +G
Sbjct: 358 ALLGAEADPIHPARIYGDLVPRLAEDAVVIGDGGDFVSFAGKFVEPKRPGGWLDPGPYGC 417
Query: 438 MGVGPGFAIAAAM 476
+G G G AIAA +
Sbjct: 418 LGAGLGAAIAARL 430
>UniRef50_Q6N658 Cluster: Possible benzaldehyde lyase; n=2;
Rhodopseudomonas palustris|Rep: Possible benzaldehyde
lyase - Rhodopseudomonas palustris
Length = 600
Score = 34.3 bits (75), Expect = 2.4
Identities = 22/75 (29%), Positives = 32/75 (42%)
Frame = +3
Query: 294 YTVFKTVQQGIPKDSIIVSEGANTMDIGRGLLLNNHPRHRLDAGTFGTMGVGPGFAIAAA 473
Y + V ++ V +G G + + P L G G +G+GPGFAI A
Sbjct: 395 YHAARAVADAAGTEAAYVFDGGEAASWGAAAAVVDRPGALLGHGYLGCLGIGPGFAIGAQ 454
Query: 474 MWCRDYAPGKRVFVL 518
+ AP +RV L
Sbjct: 455 L----AAPERRVIHL 465
>UniRef50_Q5CR51 Cluster: DHHC family palmitoyl transferase with 4
transmembrane regions; n=2; Cryptosporidium|Rep: DHHC
family palmitoyl transferase with 4 transmembrane
regions - Cryptosporidium parvum Iowa II
Length = 359
Score = 34.3 bits (75), Expect = 2.4
Identities = 15/51 (29%), Positives = 25/51 (49%)
Frame = +2
Query: 224 NRNKKQTPNL*GSSKQHCSTTELLHCFQNSSTRHSKRFNHCQRRSEYHGYW 376
N + +L SS +CS ++ H F +++H K N C R ++H W
Sbjct: 110 NPGYSEEDSLFNSSNLNCSECKICHLFFEENSKHCKLCNKCIPRYDHHCKW 160
>UniRef50_Q2NGE8 Cluster: Putative uncharacterized protein; n=1;
Methanosphaera stadtmanae DSM 3091|Rep: Putative
uncharacterized protein - Methanosphaera stadtmanae
(strain DSM 3091)
Length = 86
Score = 34.3 bits (75), Expect = 2.4
Identities = 15/35 (42%), Positives = 23/35 (65%), Gaps = 1/35 (2%)
Frame = +1
Query: 64 FRSKYLLQEFHNSKK-SELAVHSDIRPFTEALVKR 165
F +Y+ Q+ H SKK +E+ +H DI+P E + KR
Sbjct: 50 FTQEYVYQKTHTSKKITEIKMHEDIKPMLELVEKR 84
>UniRef50_A3VG64 Cluster: Acetolactate synthase large subunit; n=1;
Rhodobacterales bacterium HTCC2654|Rep: Acetolactate
synthase large subunit - Rhodobacterales bacterium
HTCC2654
Length = 539
Score = 33.9 bits (74), Expect = 3.2
Identities = 16/64 (25%), Positives = 31/64 (48%)
Frame = +3
Query: 285 LNYYTVFKTVQQGIPKDSIIVSEGANTMDIGRGLLLNNHPRHRLDAGTFGTMGVGPGFAI 464
+++ T + +P D +V++ M GLL PR + + +FG +G+G A+
Sbjct: 358 VDFLTTLARLNDILPSDRTLVTDAGRWMVKSYGLLTAPGPRDHVTSASFGAIGLGLATAV 417
Query: 465 AAAM 476
A +
Sbjct: 418 GAGV 421
>UniRef50_UPI00006CDE0D Cluster: hypothetical protein TTHERM_00297160;
n=1; Tetrahymena thermophila SB210|Rep: hypothetical
protein TTHERM_00297160 - Tetrahymena thermophila SB210
Length = 2311
Score = 33.5 bits (73), Expect = 4.3
Identities = 21/73 (28%), Positives = 34/73 (46%)
Frame = +1
Query: 163 RLSERKFSLQPQNNSWWQGLKQKQKANTEFVRLKQAALQYH*TTTLFSKQFNKAFQKIQS 342
R E+K Q N+WW+ K + + Q L YH + K N+ +QK +
Sbjct: 2018 RNDEKKRKSQVDPNNWWKSRYSNDKQLEKILSQTQTILDYH----IICKLQNE-YQKSYN 2072
Query: 343 LSAKERIPWILAE 381
S ++ + WIL+E
Sbjct: 2073 PSQRKPMMWILSE 2085
>UniRef50_A4A7Q3 Cluster: Acetolactate synthase large subunit; n=2;
Proteobacteria|Rep: Acetolactate synthase large subunit
- Congregibacter litoralis KT71
Length = 514
Score = 33.5 bits (73), Expect = 4.3
Identities = 20/68 (29%), Positives = 33/68 (48%)
Frame = +3
Query: 285 LNYYTVFKTVQQGIPKDSIIVSEGANTMDIGRGLLLNNHPRHRLDAGTFGTMGVGPGFAI 464
LN T+ + + +P+ +++ EGA T + + N P H T G +G G A+
Sbjct: 337 LNPLTIGQIMSNEMPEHAVVSDEGA-TCGLAMFMCTENAPAHDWLTLTGGAIGQGLPVAL 395
Query: 465 AAAMWCRD 488
AA+ C D
Sbjct: 396 GAALACPD 403
>UniRef50_Q9CFJ5 Cluster: 1-deoxyxylulose-5-phosphate synthase; n=2;
Lactococcus lactis|Rep: 1-deoxyxylulose-5-phosphate
synthase - Lactococcus lactis subsp. lactis
(Streptococcus lactis)
Length = 599
Score = 33.1 bits (72), Expect = 5.7
Identities = 24/71 (33%), Positives = 35/71 (49%), Gaps = 2/71 (2%)
Frame = +3
Query: 267 SSTAVPLNYYTVFKT-VQQGIPK-DSIIVSEGANTMDIGRGLLLNNHPRHRLDAGTFGTM 440
SST + +Y VF +++ + K D++I A M G NHP++ +D G
Sbjct: 277 SSTNIVRSYNNVFLDFMEEKLAKGDNLIAINAAIPMFFGLSQFAKNHPKNYVDGGIAEQY 336
Query: 441 GVGPGFAIAAA 473
V G AIAAA
Sbjct: 337 TVTLGGAIAAA 347
>UniRef50_Q3XZD0 Cluster: Pyruvate decarboxylase; n=3;
Lactobacillales|Rep: Pyruvate decarboxylase -
Enterococcus faecium DO
Length = 576
Score = 33.1 bits (72), Expect = 5.7
Identities = 26/79 (32%), Positives = 37/79 (46%)
Frame = +3
Query: 282 PLNYYTVFKTVQQGIPKDSIIVSEGANTMDIGRGLLLNNHPRHRLDAGTFGTMGVGPGFA 461
P+ V+K + + D+I V++ NT LL N + +G F TMG G
Sbjct: 359 PIRPEAVYKEINRIAEDDAIFVTDVGNTTIHSIRLLNMNGKQKHTTSGWFATMGNGVPGG 418
Query: 462 IAAAMWCRDYAPGKRVFVL 518
IAA + Y P K+VF L
Sbjct: 419 IAAQL---SY-PEKQVFTL 433
>UniRef50_A3VND4 Cluster: Sensor protein; n=1; Parvularcula
bermudensis HTCC2503|Rep: Sensor protein - Parvularcula
bermudensis HTCC2503
Length = 1044
Score = 33.1 bits (72), Expect = 5.7
Identities = 12/30 (40%), Positives = 19/30 (63%)
Frame = +2
Query: 356 SEYHGYWPRFIAQQSSETQARCWYIWHYGG 445
+ ++GYW FIA++ ET + W + YGG
Sbjct: 275 ANHNGYWEWFIAEEVEETSDQFWRLIGYGG 304
>UniRef50_UPI0000499DA2 Cluster: conserved hypothetical protein;
n=1; Entamoeba histolytica HM-1:IMSS|Rep: conserved
hypothetical protein - Entamoeba histolytica HM-1:IMSS
Length = 509
Score = 32.7 bits (71), Expect = 7.5
Identities = 18/56 (32%), Positives = 31/56 (55%), Gaps = 3/56 (5%)
Frame = +1
Query: 64 FRSKYLLQE-FHNSKKSELAV--HSDIRPFTEALVKRLSERKFSLQPQNNSWWQGL 222
F + YLL+E ++ KK+ + + IRP +L+ RLSE+ S+ W+ G+
Sbjct: 213 FNNDYLLEEIYYELKKAIKGIKYQNIIRPHFSSLLSRLSEKAVSMDNSQMHWFYGI 268
>UniRef50_A4ABB6 Cluster: Pyruvate decarboxylase; n=2;
Proteobacteria|Rep: Pyruvate decarboxylase -
Congregibacter litoralis KT71
Length = 565
Score = 32.7 bits (71), Expect = 7.5
Identities = 22/72 (30%), Positives = 37/72 (51%)
Frame = +3
Query: 294 YTVFKTVQQGIPKDSIIVSEGANTMDIGRGLLLNNHPRHRLDAGTFGTMGVGPGFAIAAA 473
Y++ V + +++I V +G + + R + + LD G G +GVG FA AAA
Sbjct: 365 YSLIDAVNAHVDEETIAVIDGGDILSFARVAI--SDAAALLDPGALGCIGVGGAFANAAA 422
Query: 474 MWCRDYAPGKRV 509
+ C+ P K+V
Sbjct: 423 L-CQ---PDKKV 430
>UniRef50_A2ESQ8 Cluster: Surface antigen BspA-like; n=3;
Trichomonas vaginalis G3|Rep: Surface antigen BspA-like
- Trichomonas vaginalis G3
Length = 744
Score = 32.7 bits (71), Expect = 7.5
Identities = 17/35 (48%), Positives = 24/35 (68%), Gaps = 1/35 (2%)
Frame = +2
Query: 260 SSKQHCSTTELLHCFQNSSTR-HSKRFNHCQRRSE 361
SS HCS E + F NSSTR +S+ F+HC++ S+
Sbjct: 194 SSFSHCSQLEKVR-FLNSSTRLNSQAFSHCEKLSD 227
>UniRef50_P37063 Cluster: Pyruvate oxidase; n=2; Lactobacillus
plantarum|Rep: Pyruvate oxidase - Lactobacillus
plantarum
Length = 603
Score = 32.7 bits (71), Expect = 7.5
Identities = 28/80 (35%), Positives = 40/80 (50%), Gaps = 1/80 (1%)
Frame = +3
Query: 282 PLNYYTVFKTVQQGIPKDSII-VSEGANTMDIGRGLLLNNHPRHRLDAGTFGTMGVGPGF 458
PL Y V + V + D+I + G ++ R L L RH + + F TMGVG
Sbjct: 370 PLQAYQVLRAVNKIAEPDAIYSIDVGDINLNANRHLKLTPSNRH-ITSNLFATMGVGIPG 428
Query: 459 AIAAAMWCRDYAPGKRVFVL 518
AIAA + +Y P ++VF L
Sbjct: 429 AIAAKL---NY-PERQVFNL 444
>UniRef50_UPI0000499EB4 Cluster: hypothetical protein 185.t00011;
n=1; Entamoeba histolytica HM-1:IMSS|Rep: hypothetical
protein 185.t00011 - Entamoeba histolytica HM-1:IMSS
Length = 301
Score = 32.3 bits (70), Expect = 9.9
Identities = 13/26 (50%), Positives = 17/26 (65%)
Frame = -2
Query: 497 RCIVSAPHCCCNSEARSYPHSAKCTS 420
RC+VS+ HC SE S +S KC+S
Sbjct: 199 RCLVSSTHCVSQSEEFSLEYSKKCSS 224
>UniRef50_A3X9K6 Cluster: Acetolactate synthase-like TPP-requiring
enzyme; n=1; Roseobacter sp. MED193|Rep: Acetolactate
synthase-like TPP-requiring enzyme - Roseobacter sp.
MED193
Length = 573
Score = 32.3 bits (70), Expect = 9.9
Identities = 16/50 (32%), Positives = 27/50 (54%)
Frame = +3
Query: 327 PKDSIIVSEGANTMDIGRGLLLNNHPRHRLDAGTFGTMGVGPGFAIAAAM 476
P++++ + + + G L + P R+ G GT+GVG FA+ AAM
Sbjct: 391 PENAVTIIDSGLGLASGHNLWAVHRPFSRVTPGQNGTIGVGIPFALGAAM 440
>UniRef50_A3DID9 Cluster: Acetolactate synthase; n=3;
Clostridium|Rep: Acetolactate synthase - Clostridium
thermocellum (strain ATCC 27405 / DSM 1237)
Length = 542
Score = 32.3 bits (70), Expect = 9.9
Identities = 34/153 (22%), Positives = 58/153 (37%), Gaps = 1/153 (0%)
Frame = +3
Query: 33 PPRYAPDVKIIQVEISPARISQQQEIRISSTLRH*TFYRSSCKKVVRKEVLIATSKQQLV 212
P + A +I+ ++I PA I + ++ I K+V+ KE++ + K
Sbjct: 287 PQQVAKRKQIVHIDIDPAEIGKNIDVSIPVV--------GDVKQVL-KELIDISQKGDTE 337
Query: 213 AGTETETKSKHRICEAQASSTAVPLNYYTVFKTVQQGI-PKDSIIVSEGANTMDIGRGLL 389
+T K + + E + +V G+ D II +E
Sbjct: 338 EWIKTTQKEREKHAEKPEPRPGIGFVNPKYLLSVLTGLLGDDDIITTEVGQNQIWAANYF 397
Query: 390 LNNHPRHRLDAGTFGTMGVGPGFAIAAAMWCRD 488
PR + +G GTMG G A+ A + C D
Sbjct: 398 GVKKPRTFITSGGLGTMGYGLPAAVGAKIGCPD 430
>UniRef50_Q2U8M9 Cluster: Thiamine pyrophosphate-requiring enzymes;
n=2; Trichocomaceae|Rep: Thiamine
pyrophosphate-requiring enzymes - Aspergillus oryzae
Length = 597
Score = 32.3 bits (70), Expect = 9.9
Identities = 33/149 (22%), Positives = 61/149 (40%), Gaps = 3/149 (2%)
Frame = +3
Query: 51 DVKIIQVEISPARISQQQEIRISSTLRH*TFYRSSCK--KVVRKEVLIATSKQQLVAGTE 224
D K++QV++ A I + + + + F + + + + T V G +
Sbjct: 307 DCKLVQVDVDGAEIGRTLPVDLGAICDVTQFAAGLNRHFETASFQGSVDTKWVDDVLGLK 366
Query: 225 TETKSKHRICEAQASSTAVPLNYYTVFKTVQQGIPKDSIIVSEGANTMDIGRGLLLNNHP 404
+ + E Q S P Y K + +PK+SII+ +G ++ P
Sbjct: 367 SLPSPYEQQAEVQPSGRLHP---YHALKHLLTFVPKESIIILDGGEAPLWAGEMISTCSP 423
Query: 405 RHRL-DAGTFGTMGVGPGFAIAAAMWCRD 488
+ +G G +G G G+A+ AA+ C D
Sbjct: 424 SAIVKSSGGLGFLGNGFGYALGAAVACPD 452
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 621,222,142
Number of Sequences: 1657284
Number of extensions: 12355924
Number of successful extensions: 35185
Number of sequences better than 10.0: 53
Number of HSP's better than 10.0 without gapping: 33886
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 35156
length of database: 575,637,011
effective HSP length: 97
effective length of database: 414,880,463
effective search space used: 46466611856
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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