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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= epV30140
         (516 letters)

Database: uniref50 
           1,657,284 sequences; 575,637,011 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

UniRef50_UPI0000D56A3C Cluster: PREDICTED: similar to CG15890-PA...   127   1e-28
UniRef50_Q6NPA2 Cluster: RE46682p; n=6; Endopterygota|Rep: RE466...   125   5e-28
UniRef50_UPI00015B5EEF Cluster: PREDICTED: similar to ENSANGP000...   119   5e-26
UniRef50_Q8INF8 Cluster: CG31321-PB; n=3; Sophophora|Rep: CG3132...    99   3e-20
UniRef50_UPI0000D56A21 Cluster: PREDICTED: similar to CG15890-PA...    93   3e-18
UniRef50_Q17KH2 Cluster: Adenylate cyclase; n=2; Culicidae|Rep: ...    71   1e-11
UniRef50_UPI00015B420D Cluster: PREDICTED: similar to adenylate ...    69   6e-11
UniRef50_Q7Q1Q1 Cluster: ENSANGP00000016542; n=1; Anopheles gamb...    69   6e-11
UniRef50_UPI0000D569FE Cluster: PREDICTED: similar to CG30345-PA...    68   1e-10
UniRef50_Q17E18 Cluster: Adenylate cyclase; n=1; Aedes aegypti|R...    66   4e-10
UniRef50_UPI00015B420B Cluster: PREDICTED: similar to adenylate ...    64   1e-09
UniRef50_Q961H2 Cluster: GH23453p; n=5; Sophophora|Rep: GH23453p...    62   6e-09
UniRef50_A1Z7R6 Cluster: CG8046-PA, isoform A; n=5; Sophophora|R...    61   2e-08
UniRef50_UPI0000D56BF4 Cluster: PREDICTED: similar to CG32158-PC...    60   4e-08
UniRef50_Q7SA93 Cluster: Putative uncharacterized protein NCU082...    56   5e-07
UniRef50_A6H1H8 Cluster: Major facilitator superfamily (MFS) per...    56   6e-07
UniRef50_Q17KH5 Cluster: Adenylate cyclase; n=2; Culicidae|Rep: ...    55   8e-07
UniRef50_UPI0000660680 Cluster: Thymic stromal cotransporter hom...    54   3e-06
UniRef50_Q17KH3 Cluster: Adenylate cyclase; n=1; Aedes aegypti|R...    50   4e-05
UniRef50_UPI0000E47AFF Cluster: PREDICTED: similar to D11Ertd18e...    49   6e-05
UniRef50_Q4S388 Cluster: Chromosome 4 SCAF14752, whole genome sh...    49   7e-05
UniRef50_Q9Z479 Cluster: Drug efflux protein TetA; n=3; Proteoba...    47   3e-04
UniRef50_A4RKE7 Cluster: Putative uncharacterized protein; n=1; ...    46   5e-04
UniRef50_A3UH39 Cluster: Multidrug resistance protein, putative;...    45   0.001
UniRef50_Q17ME2 Cluster: Adenylate cyclase; n=1; Aedes aegypti|R...    45   0.001
UniRef50_UPI0000F20440 Cluster: PREDICTED: hypothetical protein;...    42   0.008
UniRef50_Q16TG3 Cluster: Putative uncharacterized protein; n=1; ...    40   0.025
UniRef50_Q9BY10 Cluster: Thymic stromal cotransporter homolog; n...    40   0.025
UniRef50_A0B668 Cluster: Drug resistance transporter, Bcr/CflA s...    40   0.034
UniRef50_Q56RY7 Cluster: TetA; n=4; Acinetobacter|Rep: TetA - Ac...    36   0.55 
UniRef50_Q1CWB1 Cluster: Putative lipoprotein; n=1; Myxococcus x...    36   0.55 
UniRef50_A7RHU0 Cluster: Predicted protein; n=1; Nematostella ve...    36   0.55 
UniRef50_UPI0000584089 Cluster: PREDICTED: similar to MGC80576 p...    36   0.72 
UniRef50_A7RIK2 Cluster: Predicted protein; n=1; Nematostella ve...    36   0.72 
UniRef50_A4FEN1 Cluster: Multidrug transporter; n=1; Saccharopol...    35   0.96 
UniRef50_UPI00015B4C6B Cluster: PREDICTED: similar to sodium-dep...    35   1.3  
UniRef50_Q6BW37 Cluster: Similar to CA5023|IPF7547 Candida albic...    35   1.3  
UniRef50_A4QNU5 Cluster: Cxcr3.1 protein; n=9; Clupeocephala|Rep...    34   1.7  
UniRef50_Q46MT8 Cluster: Major facilitator superfamily MFS_1; n=...    34   1.7  
UniRef50_A5G2L8 Cluster: Major facilitator superfamily MFS_1; n=...    34   1.7  
UniRef50_A4FJA9 Cluster: Transporter, MFS superfamily; n=1; Sacc...    34   1.7  
UniRef50_A6G6F6 Cluster: NADH dehydrogenase; n=1; Plesiocystis p...    34   2.2  
UniRef50_O13714 Cluster: Uncharacterized membrane protein C14C4....    34   2.2  
UniRef50_Q6N424 Cluster: Possible bcr efflux pump, Major Facilit...    33   2.9  
UniRef50_A7RIS8 Cluster: Predicted protein; n=2; Nematostella ve...    33   2.9  
UniRef50_Q4WVN5 Cluster: MFS multidrug transporter, putative; n=...    33   2.9  
UniRef50_Q07282 Cluster: Tetracycline resistance protein, class ...    33   2.9  
UniRef50_Q8ENR4 Cluster: Hypothetical conserved protein; n=1; Oc...    33   3.9  
UniRef50_A6GGP3 Cluster: Response regulator; n=1; Plesiocystis p...    33   3.9  
UniRef50_Q9TAK8 Cluster: NADH-ubiquinone oxidoreductase chain 4;...    33   3.9  
UniRef50_Q8TPP8 Cluster: Membrane transport protein; n=3; Methan...    33   3.9  
UniRef50_P13090 Cluster: Aminotriazole resistance protein; n=12;...    33   3.9  
UniRef50_Q0EZ29 Cluster: Colicin V production protein; n=1; Mari...    33   5.1  
UniRef50_A7RP47 Cluster: Predicted protein; n=1; Nematostella ve...    33   5.1  
UniRef50_UPI00006CFE81 Cluster: major facilitator superfamily pr...    32   6.8  
UniRef50_Q4JVV2 Cluster: Putative membrane protein precursor; n=...    32   6.8  
UniRef50_Q0TI71 Cluster: Probable drug transport transmembrane p...    32   6.8  
UniRef50_Q0BZH6 Cluster: Putative membrane protein; n=1; Hyphomo...    32   6.8  
UniRef50_Q7SFA1 Cluster: Predicted protein; n=1; Neurospora cras...    32   6.8  
UniRef50_Q2UHN6 Cluster: Predicted protein; n=1; Aspergillus ory...    32   6.8  
UniRef50_UPI00006A1D1F Cluster: Protein SAAL1.; n=1; Xenopus tro...    32   8.9  
UniRef50_UPI000065EFC5 Cluster: Protein FAM5C precursor (DBCCR1-...    32   8.9  
UniRef50_Q6MQ30 Cluster: Tetracycline-efflux transporter; n=1; B...    32   8.9  
UniRef50_Q048R1 Cluster: Permease of the major facilitator super...    32   8.9  
UniRef50_Q03N16 Cluster: Beta-lactamase class A; n=3; Streptococ...    32   8.9  
UniRef50_A7I0C7 Cluster: Putative quinolone resistence protein, ...    32   8.9  
UniRef50_A0R2Y6 Cluster: Conserved membrane-spanning protein; n=...    32   8.9  

>UniRef50_UPI0000D56A3C Cluster: PREDICTED: similar to CG15890-PA;
           n=3; Coelomata|Rep: PREDICTED: similar to CG15890-PA -
           Tribolium castaneum
          Length = 666

 Score =  127 bits (307), Expect = 1e-28
 Identities = 56/152 (36%), Positives = 94/152 (61%)
 Frame = +3

Query: 18  KFGFTEVEYSIYGTINIVVGLLGTIFCILVLSKRMNVQDSIIGALAGVSRIAGCLMFALA 197
           KFG+ E++YSIY T  ++  + GT+  +++ +K + + D+ +G ++  SRI   +++A A
Sbjct: 309 KFGWNEIDYSIYSTFYVITHMFGTLLSLILFTKVLKIDDAALGVVSSASRIVASMVYAFA 368

Query: 198 PTRQWFYSAPLFNIFSFTGLTAIRSIATKSVPTEEVAKLSALMGVTESLAPSIYMPASSY 377
           P    FY   L  IF+ T   A+RSI +K VP +E+ K+++L G++E++ P IY P  S 
Sbjct: 369 PNAFTFYVGALIEIFNGTTFIAMRSIISKLVPPDELGKINSLFGLSEAMVPIIYGPLYSI 428

Query: 378 IYMSTIETFPGAFYLFDAALTVVALCLFGMIY 473
           +Y  TI   PG F++   ALTV +L +F  +Y
Sbjct: 429 VYKHTINYLPGTFFIVGGALTVPSLFIFCWLY 460


>UniRef50_Q6NPA2 Cluster: RE46682p; n=6; Endopterygota|Rep: RE46682p
           - Drosophila melanogaster (Fruit fly)
          Length = 599

 Score =  125 bits (302), Expect = 5e-28
 Identities = 57/163 (34%), Positives = 102/163 (62%), Gaps = 2/163 (1%)
 Frame = +3

Query: 18  KFGFTEVEYSIYGTINIVVGLLGTIFCILVLSKRMNVQDSIIGALAGVSRIAGCLMFALA 197
           +F ++EVE+S + T  +  GL+G IFC+ +LS ++N+ D+++G L+  S+I    ++A A
Sbjct: 356 RFNWSEVEFSFFSTYAMFTGLIGVIFCVGILSHKLNIDDALVGVLSSTSKILSSFVYAFA 415

Query: 198 PTRQWFYSAPLFNIFSFTGLTAIRSIATKSVPTEEVAKLSALMGVTESLAPSIYMPASSY 377
              +  Y   L  IF+ T   A+RSIATK V  +E+ K+++L GV E+L P ++ P  + 
Sbjct: 416 TLPRHMYLGGLVEIFNGTAFIAMRSIATKLVSKDELGKVNSLFGVAEALMPMVFAPMYTT 475

Query: 378 IYMSTIETFPGAFYLFDAALTVVALCLFGMIY--ILARKKNIA 500
           +Y +T+   PGAF+L    LT+ ++ +F  +Y   + +++N+A
Sbjct: 476 LYAATLRVLPGAFFLLGGGLTLFSVFIFLWMYRFQVRQRRNLA 518


>UniRef50_UPI00015B5EEF Cluster: PREDICTED: similar to
           ENSANGP00000027535; n=1; Nasonia vitripennis|Rep:
           PREDICTED: similar to ENSANGP00000027535 - Nasonia
           vitripennis
          Length = 593

 Score =  119 bits (286), Expect = 5e-26
 Identities = 55/157 (35%), Positives = 94/157 (59%)
 Frame = +3

Query: 18  KFGFTEVEYSIYGTINIVVGLLGTIFCILVLSKRMNVQDSIIGALAGVSRIAGCLMFALA 197
           ++ + EV++S Y T ++V+ L+GT+F + V S  + + D+++G L+ VS+I    ++A +
Sbjct: 370 RYRWNEVQFSFYSTYSMVINLIGTLFAVGVFSHFLKMDDALLGVLSCVSKILASFVYAFS 429

Query: 198 PTRQWFYSAPLFNIFSFTGLTAIRSIATKSVPTEEVAKLSALMGVTESLAPSIYMPASSY 377
            T    Y APL  I + T    +RSI +K VP +E+ K+++L GV E++ P +Y P  S 
Sbjct: 430 TTDWMMYIAPLVEIINGTSFIVMRSITSKLVPPDELGKVNSLFGVCEAIVPLVYGPMYSS 489

Query: 378 IYMSTIETFPGAFYLFDAALTVVALCLFGMIYILARK 488
           IY +T+  FPG F+L    L +  +  F  +Y+  RK
Sbjct: 490 IYGATVNNFPGTFFLVGGGLMIPGVIAFLWLYMEHRK 526


>UniRef50_Q8INF8 Cluster: CG31321-PB; n=3; Sophophora|Rep:
           CG31321-PB - Drosophila melanogaster (Fruit fly)
          Length = 601

 Score =   99 bits (238), Expect = 3e-20
 Identities = 50/158 (31%), Positives = 93/158 (58%)
 Frame = +3

Query: 18  KFGFTEVEYSIYGTINIVVGLLGTIFCILVLSKRMNVQDSIIGALAGVSRIAGCLMFALA 197
           K  +   ++SIY T++    L+GT     +LSK + V DS+IG L+ +S +   ++FA +
Sbjct: 410 KLAWNGNDFSIYLTLSSGAALVGTFIGTAILSKLLKVSDSMIGMLSALSIVCSRVLFAFS 469

Query: 198 PTRQWFYSAPLFNIFSFTGLTAIRSIATKSVPTEEVAKLSALMGVTESLAPSIYMPASSY 377
            +   FY A + ++F    + AI++I +  V  +E++K+ ++ G++E +A  I+ P  S 
Sbjct: 470 SSTASFYVAGVVDMFVSLRVIAIKTIGSSIVAGDELSKMYSIFGISEPIAQFIFPPIFSE 529

Query: 378 IYMSTIETFPGAFYLFDAALTVVALCLFGMIYILARKK 491
           IY ST+++FPGA +LF     +  + +F + Y L R++
Sbjct: 530 IYKSTVDSFPGAIWLFGEIFYIPNVLVFVVCYFLLRRR 567


>UniRef50_UPI0000D56A21 Cluster: PREDICTED: similar to CG15890-PA;
           n=1; Tribolium castaneum|Rep: PREDICTED: similar to
           CG15890-PA - Tribolium castaneum
          Length = 505

 Score = 93.5 bits (222), Expect = 3e-18
 Identities = 51/160 (31%), Positives = 92/160 (57%), Gaps = 1/160 (0%)
 Frame = +3

Query: 15  GKFGFTEVEYSIYGTINIVVGLLGTIFCILVLSKRMNVQDSIIGALAGVSRIAGCLMFAL 194
           G F +  +EYS + TIN V+ L+GT+  + + +K +++ D +I  +  V +I   ++F L
Sbjct: 320 GFFNWGPLEYSYFITINTVIHLVGTLIGVPLFTKFLSLGDLMILLITFVDKIVTNIVFGL 379

Query: 195 APTRQWFYSAPLFNIFSFTGLTAIRSIATKSVPTEEVAKLSALMGVTESLAPSIYMPA-S 371
           A T    Y A   +I +     AIRS+ATK V  E++ K  +L G+ E++ P+I  P  +
Sbjct: 380 AKTDVMLYVATAVSIITGISNIAIRSLATKVVSQEDLGKAQSLFGICEAIGPAIAAPLYN 439

Query: 372 SYIYMSTIETFPGAFYLFDAALTVVALCLFGMIYILARKK 491
             IY+++++T P A++ F A L V+ L +   +Y  ++ +
Sbjct: 440 KAIYLNSLDTLPSAYFYFGAILHVLLLVVIIWMYYASKSE 479


>UniRef50_Q17KH2 Cluster: Adenylate cyclase; n=2; Culicidae|Rep:
           Adenylate cyclase - Aedes aegypti (Yellowfever mosquito)
          Length = 483

 Score = 71.3 bits (167), Expect = 1e-11
 Identities = 40/147 (27%), Positives = 68/147 (46%)
 Frame = +3

Query: 18  KFGFTEVEYSIYGTINIVVGLLGTIFCILVLSKRMNVQDSIIGALAGVSRIAGCLMFALA 197
           +FG+T  EYS Y    IV  ++G +  I  + K  N+ +S++ A+   S      + A+A
Sbjct: 317 RFGWTVKEYSFYDATAIVFMIIGNLVAIYGVKKLFNLSESVLAAIGFCSYAIASAIHAIA 376

Query: 198 PTRQWFYSAPLFNIFSFTGLTAIRSIATKSVPTEEVAKLSALMGVTESLAPSIYMPASSY 377
                 Y     ++         R++ + + P  ++ K+ +L    ESL P    P  +Y
Sbjct: 377 YEPWHLYLGIGVSMMKGIAGPMGRAVISNTAPPSDIGKIFSLTTSIESLTPLASAPIYTY 436

Query: 378 IYMSTIETFPGAFYLFDAALTVVALCL 458
           +Y  T+  +PGAF L  A +    LCL
Sbjct: 437 VYKQTMSWYPGAFNLISATVFFFCLCL 463


>UniRef50_UPI00015B420D Cluster: PREDICTED: similar to adenylate
           cyclase; n=1; Nasonia vitripennis|Rep: PREDICTED:
           similar to adenylate cyclase - Nasonia vitripennis
          Length = 433

 Score = 68.9 bits (161), Expect = 6e-11
 Identities = 38/160 (23%), Positives = 79/160 (49%)
 Frame = +3

Query: 18  KFGFTEVEYSIYGTINIVVGLLGTIFCILVLSKRMNVQDSIIGALAGVSRIAGCLMFALA 197
           +FG++ +++S Y  +++ V ++G +  I +++  + + +++   +A +S     L  A A
Sbjct: 265 RFGWSIMDFSTYSVVHLSVNMIGMMLLIKIIAPYLKLPETVSIIIASLSNNGNALAKAFA 324

Query: 198 PTRQWFYSAPLFNIFSFTGLTAIRSIATKSVPTEEVAKLSALMGVTESLAPSIYMPASSY 377
                 Y A    IFS    + +RSI +K++   +V K  A+    E + P I  P    
Sbjct: 325 RQSWHMYLATGIGIFSLAPASLVRSIISKTIAKHDVGKAFAITTTVEKIGPFITTPLFVL 384

Query: 378 IYMSTIETFPGAFYLFDAALTVVALCLFGMIYILARKKNI 497
           ++ + I+T+P   +   A LT V + L  +++   R+  I
Sbjct: 385 LHTNFIKTYPCPVWFLPAVLTWVNIILAIIVHYRWRRLRI 424


>UniRef50_Q7Q1Q1 Cluster: ENSANGP00000016542; n=1; Anopheles gambiae
           str. PEST|Rep: ENSANGP00000016542 - Anopheles gambiae
           str. PEST
          Length = 398

 Score = 68.9 bits (161), Expect = 6e-11
 Identities = 38/136 (27%), Positives = 76/136 (55%), Gaps = 3/136 (2%)
 Frame = +3

Query: 63  NIVVGLLGTIFCILVLSKRMNVQDSIIGALAGVSRIAGCLMFALAPTR---QWFYSAPLF 233
           +++  +LGT+  + VLSKR+ V D++I   +    + G  + A+A +      +Y A   
Sbjct: 262 DLLTTMLGTLLAMGVLSKRLGVSDAMICVFSVCFSLVGKPIMAIAVSTVKPYLYYVATSI 321

Query: 234 NIFSFTGLTAIRSIATKSVPTEEVAKLSALMGVTESLAPSIYMPASSYIYMSTIETFPGA 413
           ++F  + + AIRSI +K V  +E+ K+ +++G+ +S   +IY    S +Y+ +   F G+
Sbjct: 322 DVFEGSKMIAIRSIVSKLVGQDEIGKMLSILGIVDSAQVAIYPTIYSTVYLKSQSFFIGS 381

Query: 414 FYLFDAALTVVALCLF 461
            +L   A  +V+L ++
Sbjct: 382 VFLLSEAFLLVSLGIY 397


>UniRef50_UPI0000D569FE Cluster: PREDICTED: similar to CG30345-PA;
           n=1; Tribolium castaneum|Rep: PREDICTED: similar to
           CG30345-PA - Tribolium castaneum
          Length = 477

 Score = 67.7 bits (158), Expect = 1e-10
 Identities = 46/165 (27%), Positives = 79/165 (47%)
 Frame = +3

Query: 18  KFGFTEVEYSIYGTINIVVGLLGTIFCILVLSKRMNVQDSIIGALAGVSRIAGCLMFALA 197
           KF ++  +Y+++   + V  +LGT   I +L K + + ++++  +  +S   G L+  LA
Sbjct: 292 KFHWSLEQYTLFSAAHNVTWVLGTAVGIYLLHKLLKIPETVMIVIGFISMFIGALVMGLA 351

Query: 198 PTRQWFYSAPLFNIFSFTGLTAIRSIATKSVPTEEVAKLSALMGVTESLAPSIYMPASSY 377
                 Y+A             +RS+ +K VP +E+ K+ AL+  TESL      P  + 
Sbjct: 352 IYSWQVYAAAFSRALGGVLSPMVRSLVSKIVPNDEIGKVFALIVATESLIGMGGSPIFTA 411

Query: 378 IYMSTIETFPGAFYLFDAALTVVALCLFGMIYILARKKNIALSAN 512
           IY +TI T  G F    A + VV + L  +  IL R    + + N
Sbjct: 412 IYNTTISTDAGIFNFVAAGVYVVEI-LIAIGIILVRNVTTSTTEN 455


>UniRef50_Q17E18 Cluster: Adenylate cyclase; n=1; Aedes aegypti|Rep:
           Adenylate cyclase - Aedes aegypti (Yellowfever mosquito)
          Length = 389

 Score = 66.1 bits (154), Expect = 4e-10
 Identities = 44/141 (31%), Positives = 75/141 (53%), Gaps = 3/141 (2%)
 Frame = +3

Query: 48  IYGTINIVVGLLGTIFCILVLSKRMNVQDSIIGALAGV-SRIAGCLM-FALAPTRQ-WFY 218
           I+G  + +   LGT+  I VL KR  V D  I A +   + IA  +M +A++  +  +FY
Sbjct: 241 IWGAYDALTTQLGTMLAIGVLGKRFGVSDYFICAFSVCFTLIAKPIMAYAVSTLKDHFFY 300

Query: 219 SAPLFNIFSFTGLTAIRSIATKSVPTEEVAKLSALMGVTESLAPSIYMPASSYIYMSTIE 398
            A   +IF  +   AIRSI +K V   E+ K+++L+GV  S    +Y    S +++ + +
Sbjct: 301 VATSIDIFDGSKTVAIRSIVSKLVEQNEIGKINSLLGVIASAQSIVYPTIYSVVFLQSRD 360

Query: 399 TFPGAFYLFDAALTVVALCLF 461
            F GA ++      +V+L L+
Sbjct: 361 IFIGAVFMLAEVFLLVSLGLY 381


>UniRef50_UPI00015B420B Cluster: PREDICTED: similar to adenylate
           cyclase; n=1; Nasonia vitripennis|Rep: PREDICTED:
           similar to adenylate cyclase - Nasonia vitripennis
          Length = 461

 Score = 64.5 bits (150), Expect = 1e-09
 Identities = 39/147 (26%), Positives = 68/147 (46%)
 Frame = +3

Query: 18  KFGFTEVEYSIYGTINIVVGLLGTIFCILVLSKRMNVQDSIIGALAGVSRIAGCLMFALA 197
           K G+   +YS Y    +V+ + G +  I V+   + + +++I  L+ +S     L  A  
Sbjct: 291 KLGWNVSQYSAYSAAQMVMSIGGMLLIIRVVGSLLKLPETVIIILSCLSTSVTGLAKAFV 350

Query: 198 PTRQWFYSAPLFNIFSFTGLTAIRSIATKSVPTEEVAKLSALMGVTESLAPSIYMPASSY 377
                 Y +    +FS +    IRSI +KSVP +++ K  +L+   E   P    P   Y
Sbjct: 351 YKPWHMYFSASIGMFSSSATPVIRSIVSKSVPPQDLGKTFSLITTMEMTIPFATTPLYIY 410

Query: 378 IYMSTIETFPGAFYLFDAALTVVALCL 458
           +Y  T++ +P   +   AAL V  + L
Sbjct: 411 VYTHTLKYYPCPVWFLSAALPVFIIIL 437


>UniRef50_Q961H2 Cluster: GH23453p; n=5; Sophophora|Rep: GH23453p -
           Drosophila melanogaster (Fruit fly)
          Length = 507

 Score = 62.5 bits (145), Expect = 6e-09
 Identities = 41/152 (26%), Positives = 71/152 (46%)
 Frame = +3

Query: 18  KFGFTEVEYSIYGTINIVVGLLGTIFCILVLSKRMNVQDSIIGALAGVSRIAGCLMFALA 197
           KF +T  ++S++    IV+ ++G+I  +LVL + + +    +  L+    +    + A A
Sbjct: 339 KFNWTIKDFSLFNASRIVIQIVGSIVGMLVLRRVLKMSIVTMAMLSLACCVLESTVRATA 398

Query: 198 PTRQWFYSAPLFNIFSFTGLTAIRSIATKSVPTEEVAKLSALMGVTESLAPSIYMPASSY 377
              Q  Y      +         R+I +   P  EV K+ AL    ES++P    P  + 
Sbjct: 399 VYWQELYLGMTLGMMRGVMGPMCRAILSHVAPATEVGKIFALTTSMESVSPLGAAPLYTT 458

Query: 378 IYMSTIETFPGAFYLFDAALTVVALCLFGMIY 473
           +Y +T+E +PGAF    AAL  V   L  +I+
Sbjct: 459 VYKATLENYPGAFNFISAALYFVCYILIAVIF 490


>UniRef50_A1Z7R6 Cluster: CG8046-PA, isoform A; n=5; Sophophora|Rep:
           CG8046-PA, isoform A - Drosophila melanogaster (Fruit
           fly)
          Length = 519

 Score = 60.9 bits (141), Expect = 2e-08
 Identities = 45/155 (29%), Positives = 73/155 (47%), Gaps = 3/155 (1%)
 Frame = +3

Query: 18  KFGFTEVEYSIYGTINIVVGLLGTIFCILVLSKRMNVQDSIIGALAGVSRIAGC---LMF 188
           KF +T  +++ Y T+ I+V  +     +L +       +S I  LA VS ++ C   LM 
Sbjct: 350 KFHWTVKQFTEYETVGILVPAVAGSGGVLFIWSLRKCTNSAILWLALVSLLSHCSSSLMK 409

Query: 189 ALAPTRQWFYSAPLFNIFSFTGLTAIRSIATKSVPTEEVAKLSALMGVTESLAPSIYMPA 368
             A      Y A    +F        R++ T  +P +E  K+ AL+GV ++L+P I    
Sbjct: 410 GFALESWQIYVAIGLGVFKSLVNPMCRTMITNLLPADERGKIFALLGVLQALSPLISSTL 469

Query: 369 SSYIYMSTIETFPGAFYLFDAALTVVALCLFGMIY 473
              IY  T+ T PG F +F A L  + + L G ++
Sbjct: 470 YVAIYTRTLNTEPGIFNVFSAFLFGIGIILLGTVW 504


>UniRef50_UPI0000D56BF4 Cluster: PREDICTED: similar to CG32158-PC,
           isoform C; n=2; Endopterygota|Rep: PREDICTED: similar to
           CG32158-PC, isoform C - Tribolium castaneum
          Length = 478

 Score = 59.7 bits (138), Expect = 4e-08
 Identities = 44/149 (29%), Positives = 71/149 (47%), Gaps = 2/149 (1%)
 Frame = +3

Query: 21  FGFTEVEYSIYGTINIVVGLLGTIFCILVLSKRMNVQDSIIGALAGVSRIAGCLMFALAP 200
           F +T  E+S + T+   +  +  +  I ++S+ +  +D+II  +  ++   G + FA A 
Sbjct: 305 FKWTFDEFSNFRTVQSAIQDVFLLCAIPLMSRVLGWRDTIIIMIGALAHSVGRIFFATAD 364

Query: 201 TRQWFYSAPLFNIFSFTGLTAIRSIATKSVPTEEVAKLSALMGVTESLAPSIYMPASSYI 380
               FY   +F          IRS+ +K V   E  K  A++ V ++  P I     S +
Sbjct: 365 ESWMFYLGGVFAAIGPIVAPVIRSMVSKLVANSEKGKTLAVLAVADNAIPLISGTMYSKV 424

Query: 381 YMSTIETFPGA-FYLFDAA-LTVVALCLF 461
           Y +TI T P A FYL  A  +TV  L LF
Sbjct: 425 YNATIHTHPNAIFYLTMATQMTVFVLILF 453


>UniRef50_Q7SA93 Cluster: Putative uncharacterized protein
           NCU08292.1; n=2; Sordariales|Rep: Putative
           uncharacterized protein NCU08292.1 - Neurospora crassa
          Length = 621

 Score = 56.0 bits (129), Expect = 5e-07
 Identities = 28/98 (28%), Positives = 53/98 (54%)
 Frame = +3

Query: 159 VSRIAGCLMFALAPTRQWFYSAPLFNIFSFTGLTAIRSIATKSVPTEEVAKLSALMGVTE 338
           +S + G   +  A T++WF  + +   F   G  +I++  +K VPTE V +L   +G+  
Sbjct: 478 ISDVIGIGGYIFARTQEWFILSAVIAAFGGLGSASIQASISKHVPTERVGQLLGAVGLLH 537

Query: 339 SLAPSIYMPASSYIYMSTIETFPGAFYLFDAALTVVAL 452
           +LA   +    + +Y +T+ T+P AF++   ++  VAL
Sbjct: 538 ALARVFFPIIFNGLYAATVSTYPQAFFVLLCSIFAVAL 575


>UniRef50_A6H1H8 Cluster: Major facilitator superfamily (MFS)
           permease; n=1; Flavobacterium psychrophilum
           JIP02/86|Rep: Major facilitator superfamily (MFS)
           permease - Flavobacterium psychrophilum (strain JIP02/86
           / ATCC 49511)
          Length = 411

 Score = 55.6 bits (128), Expect = 6e-07
 Identities = 45/155 (29%), Positives = 80/155 (51%), Gaps = 7/155 (4%)
 Frame = +3

Query: 18  KFGFTEVEYSI--YGTINIVVGLLGTIFCILVLSKRMNVQDSIIGALAGVSRIAGCLMFA 191
           K+  + V YS+   G ++I+V L    + + +L+K+++  D  +  L  V  + G  +FA
Sbjct: 247 KWSTSLVGYSLAFIGILSIIVQL----WLVSILAKKLS--DKRMAVLGFVLMMTGFFLFA 300

Query: 192 LAPTRQWFYSAPLFNIFSFTGLTAIRSIATKSVPTEEVAK----LSALMGVTESLAPSIY 359
             P +   ++A L  I      TA++SI + ++P  E  +    L +LMG+T  +AP + 
Sbjct: 301 FTPWQWLLFTALLLFIVGGIQGTAVQSIMSSAMPDNEQGELQGALGSLMGLTTLIAPPLM 360

Query: 360 MPASSYIYMSTIET-FPGAFYLFDAALTVVALCLF 461
             + SY      E  FPG  +L  + LT+++L LF
Sbjct: 361 TSSFSYFTGKQSEIYFPGIPFLIASILTLISLILF 395


>UniRef50_Q17KH5 Cluster: Adenylate cyclase; n=2; Culicidae|Rep:
           Adenylate cyclase - Aedes aegypti (Yellowfever mosquito)
          Length = 514

 Score = 55.2 bits (127), Expect = 8e-07
 Identities = 35/158 (22%), Positives = 74/158 (46%)
 Frame = +3

Query: 18  KFGFTEVEYSIYGTINIVVGLLGTIFCILVLSKRMNVQDSIIGALAGVSRIAGCLMFALA 197
           KF +T  +Y+++ + +++  ++G    IL+L K   + D  I  ++ +       +  LA
Sbjct: 339 KFNWTLEQYTMWQSADLLSIIVGNFLGILILKKVFKLPDIAIAFVSVLCFSGDSFIKGLA 398

Query: 198 PTRQWFYSAPLFNIFSFTGLTAIRSIATKSVPTEEVAKLSALMGVTESLAPSIYMPASSY 377
                 Y A        T   A+ ++++  +P+ ++AK+ ++     +  P    P  +Y
Sbjct: 399 SHGWQLYLATGVTPLKGTEGAALMTLSSNILPSHDIAKVYSMAMSLTATVPLAAAPLFTY 458

Query: 378 IYMSTIETFPGAFYLFDAALTVVALCLFGMIYILARKK 491
           IY  T+ T P AF    + +  V +   G+I+IL + +
Sbjct: 459 IYNQTLTTAPEAFNFVASGIYAVNILFVGIIHILLKNR 496


>UniRef50_UPI0000660680 Cluster: Thymic stromal cotransporter
           homolog.; n=1; Takifugu rubripes|Rep: Thymic stromal
           cotransporter homolog. - Takifugu rubripes
          Length = 438

 Score = 53.6 bits (123), Expect = 3e-06
 Identities = 31/130 (23%), Positives = 60/130 (46%)
 Frame = +3

Query: 87  TIFCILVLSKRMNVQDSIIGALAGVSRIAGCLMFALAPTRQWFYSAPLFNIFSFTGLTAI 266
           T F  L+L +R  + D  +  +  +S  +G    A   +   FY A    +F+   +  I
Sbjct: 305 TSFLGLLLFRRC-MNDVTLVLIGMISFASGIFFMAFVRSTTTFYLARSLTLFALIPMPTI 363

Query: 267 RSIATKSVPTEEVAKLSALMGVTESLAPSIYMPASSYIYMSTIETFPGAFYLFDAALTVV 446
           RS+ +K VP          + ++      IY+P  + IY  T++ FPG  ++  + +TV+
Sbjct: 364 RSLLSKQVPASSCGMTLTGLQLSLKFMGLIYIPVFTKIYQGTLDGFPGLVFMLSSIVTVL 423

Query: 447 ALCLFGMIYI 476
           A+    ++ +
Sbjct: 424 AMVPIRLVLV 433


>UniRef50_Q17KH3 Cluster: Adenylate cyclase; n=1; Aedes aegypti|Rep:
           Adenylate cyclase - Aedes aegypti (Yellowfever mosquito)
          Length = 481

 Score = 49.6 bits (113), Expect = 4e-05
 Identities = 34/163 (20%), Positives = 71/163 (43%), Gaps = 2/163 (1%)
 Frame = +3

Query: 18  KFGFTEVEYSIYGTINIVVGLLGTIFCILVLSKRMNVQDSIIGALAGVSRIAGCLMFALA 197
           +F +   +YS Y +   V+ +LG +    VL + + + ++ I ++   S +   ++ A+A
Sbjct: 315 QFNWAVRKYSFYASAETVLLVLGNLLATYVLERLIGLTEAAIASIGFFSWMLNSIVIAVA 374

Query: 198 PTRQWFYSAPLFNIFSFTGLT--AIRSIATKSVPTEEVAKLSALMGVTESLAPSIYMPAS 371
            T  W     +  I    G T    R+  +K    E++  + +     E+L P    P  
Sbjct: 375 -TEPWHLYLAI-TICMLKGATDPMTRAFISKGASPEDMGSIFSFSSTFEALMPLGAAPLY 432

Query: 372 SYIYMSTIETFPGAFYLFDAALTVVALCLFGMIYILARKKNIA 500
           + +Y  T+   PGAF      +  +  CL   + +L   ++++
Sbjct: 433 TNVYKHTLSWHPGAFSWISTGVYGLCYCLTMCVCVLQAMRHLS 475


>UniRef50_UPI0000E47AFF Cluster: PREDICTED: similar to D11Ertd18e
           protein; n=1; Strongylocentrotus purpuratus|Rep:
           PREDICTED: similar to D11Ertd18e protein -
           Strongylocentrotus purpuratus
          Length = 484

 Score = 49.2 bits (112), Expect = 6e-05
 Identities = 38/153 (24%), Positives = 69/153 (45%), Gaps = 5/153 (3%)
 Frame = +3

Query: 21  FGFTEVEYSIYGTINIVVGLLGT-----IFCILVLSKRMNVQDSIIGALAGVSRIAGCLM 185
           F +  V    Y T ++ +  +GT     IF    L     +Q SI+  LA    +A    
Sbjct: 28  FCWDSVTIGFYITTSLAIPGIGTVSGAGIFQWCKLGYLWIIQISILSCLANTLALA--FT 85

Query: 186 FALAPTRQWFYSAPLFNIFSFTGLTAIRSIATKSVPTEEVAKLSALMGVTESLAPSIYMP 365
           + +  T  + +++    +F   G+  IR+  +  V   E   L AL+GV + L   + +P
Sbjct: 86  YVIQSTI-FIFASSFLGLFRLLGVPVIRTFLSAVVQEHEHGALFALLGVLDGLCSFLALP 144

Query: 366 ASSYIYMSTIETFPGAFYLFDAALTVVALCLFG 464
             + +Y STI+    A + F +AL  +++ + G
Sbjct: 145 IVNGVYYSTIDVLSTAVFFFMSALLFISIIITG 177


>UniRef50_Q4S388 Cluster: Chromosome 4 SCAF14752, whole genome
           shotgun sequence; n=2; Tetraodon nigroviridis|Rep:
           Chromosome 4 SCAF14752, whole genome shotgun sequence -
           Tetraodon nigroviridis (Green puffer)
          Length = 444

 Score = 48.8 bits (111), Expect = 7e-05
 Identities = 21/73 (28%), Positives = 38/73 (52%)
 Frame = +3

Query: 234 NIFSFTGLTAIRSIATKSVPTEEVAKLSALMGVTESLAPSIYMPASSYIYMSTIETFPGA 413
           N+F+   +  IRS+ +K VP+         + +    A   Y+PA + +Y  T++ FPG 
Sbjct: 368 NLFALIPMPTIRSLLSKQVPSSSCGMTLTFLQLALKFAGLAYIPAFTQLYQRTLDWFPGL 427

Query: 414 FYLFDAALTVVAL 452
            ++  + LTVV +
Sbjct: 428 VFMLSSVLTVVGM 440


>UniRef50_Q9Z479 Cluster: Drug efflux protein TetA; n=3;
           Proteobacteria|Rep: Drug efflux protein TetA -
           Agrobacterium tumefaciens
          Length = 394

 Score = 46.8 bits (106), Expect = 3e-04
 Identities = 38/151 (25%), Positives = 71/151 (47%)
 Frame = +3

Query: 18  KFGFTEVEYSIYGTINIVVGLLGTIFCILVLSKRMNVQDSIIGALAGVSRIAGCLMFALA 197
           +FG+  V   +  ++  V G L   F +  LS+R     +++  + G   +A  LM    
Sbjct: 238 RFGWDSVHMGLSLSVFGVSGALAQAFLVGPLSRRFGDLGTLMIGV-GFDMLAYMLMAFAN 296

Query: 198 PTRQWFYSAPLFNIFSFTGLTAIRSIATKSVPTEEVAKLSALMGVTESLAPSIYMPASSY 377
            +   +  APLF +     + A++S+ T  V  ++  +L  ++    SLA  I    ++ 
Sbjct: 297 QSWMGYAVAPLFALGG-VAMPALQSLVTSRVSDDQQGQLQGVLASLMSLAGIIGPVLTTA 355

Query: 378 IYMSTIETFPGAFYLFDAALTVVALCLFGMI 470
           ++ ST   + G  +L  AAL ++AL LF  +
Sbjct: 356 VFFSTKSIWIGTIWLVGAALYLLALPLFATV 386


>UniRef50_A4RKE7 Cluster: Putative uncharacterized protein; n=1;
           Magnaporthe grisea|Rep: Putative uncharacterized protein
           - Magnaporthe grisea (Rice blast fungus) (Pyricularia
           grisea)
          Length = 606

 Score = 46.0 bits (104), Expect = 5e-04
 Identities = 23/64 (35%), Positives = 38/64 (59%)
 Frame = +3

Query: 267 RSIATKSVPTEEVAKLSALMGVTESLAPSIYMPASSYIYMSTIETFPGAFYLFDAALTVV 446
           +S  TK VP ++V  L   +G+  +LA  ++  A S +Y +T+E+FP A Y+    + V+
Sbjct: 498 QSALTKHVPADQVGSLLGAIGLLHALARVLFPLAISGLYAATVESFPQAVYVLLVVIFVL 557

Query: 447 ALCL 458
           AL L
Sbjct: 558 ALSL 561


>UniRef50_A3UH39 Cluster: Multidrug resistance protein, putative;
           n=2; Hyphomonadaceae|Rep: Multidrug resistance protein,
           putative - Oceanicaulis alexandrii HTCC2633
          Length = 428

 Score = 44.8 bits (101), Expect = 0.001
 Identities = 41/158 (25%), Positives = 66/158 (41%), Gaps = 4/158 (2%)
 Frame = +3

Query: 54  GTINIVVGLLGTIFCILVLSKRMNVQDSIIGALAGVSRIAGCLMFALAPTRQWFYSAPLF 233
           G+I + +G  G IF  LV+   +N    ++  +  V  + G      AP         +F
Sbjct: 272 GSIALTMGAAGLIFAQLVVIPVLNTSPRVLMIIGAVMVVLGNATMIFAPNYVVIVIGYMF 331

Query: 234 NIFSF----TGLTAIRSIATKSVPTEEVAKLSALMGVTESLAPSIYMPASSYIYMSTIET 401
           N F F    +G TA  S+A   V  EE  + + L   T  +   I      ++Y S    
Sbjct: 332 NSFGFGLARSGFTAGASLA---VEPEEQGRAAGLTTATAGVGFMIAPITGLWLYQSVA-- 386

Query: 402 FPGAFYLFDAALTVVALCLFGMIYILARKKNIALSANV 515
            P A +  +A+L V+  C   +++   R+   AL  NV
Sbjct: 387 -PAAPFELNASLAVIG-CALALLHPRVRETTAALVPNV 422


>UniRef50_Q17ME2 Cluster: Adenylate cyclase; n=1; Aedes aegypti|Rep:
           Adenylate cyclase - Aedes aegypti (Yellowfever mosquito)
          Length = 492

 Score = 44.8 bits (101), Expect = 0.001
 Identities = 32/158 (20%), Positives = 63/158 (39%)
 Frame = +3

Query: 18  KFGFTEVEYSIYGTINIVVGLLGTIFCILVLSKRMNVQDSIIGALAGVSRIAGCLMFALA 197
           KF +    YS + T      ++     +   +K + ++D+ I  +   +      ++  A
Sbjct: 304 KFNWNADLYSYFKTYQSAAYVVMMFLGVPFFTKILQMKDTFIIMIGATAHAMARFVYIFA 363

Query: 198 PTRQWFYSAPLFNIFSFTGLTAIRSIATKSVPTEEVAKLSALMGVTESLAPSIYMPASSY 377
                 Y     +         +RS+ +K VPT E   + + + V ++  P +     + 
Sbjct: 364 EVDWLLYVGASISSLGPVVAPVLRSMISKMVPTTERGIIFSFLSVFDNAVPLVSGVLYTQ 423

Query: 378 IYMSTIETFPGAFYLFDAALTVVALCLFGMIYILARKK 491
           IY ++I +FP AF+L       V   L   ++I  R K
Sbjct: 424 IYNASINSFPQAFFLLTMGTQAVVFLLTMGVHIALRGK 461


>UniRef50_UPI0000F20440 Cluster: PREDICTED: hypothetical protein;
           n=1; Danio rerio|Rep: PREDICTED: hypothetical protein -
           Danio rerio
          Length = 448

 Score = 41.9 bits (94), Expect = 0.008
 Identities = 34/147 (23%), Positives = 68/147 (46%), Gaps = 3/147 (2%)
 Frame = +3

Query: 27  FTEVEYSIYGTINIVV---GLLGTIFCILVLSKRMNVQDSIIGALAGVSRIAGCLMFALA 197
           FT   + ++ ++ +++   GLLG +F +L+      V++  +  L+ V RIA  ++ AL+
Sbjct: 305 FTTALFGVFNSVKMLLLGFGLLG-LFPLLMRC----VKEMTLAKLSAVFRIASYILLALS 359

Query: 198 PTRQWFYSAPLFNIFSFTGLTAIRSIATKSVPTEEVAKLSALMGVTESLAPSIYMPASSY 377
                 +   +    S      IRS+++  V  +E   + +     E+    I     + 
Sbjct: 360 NNTWMVFLVAVVGAPSGISQAVIRSLSSAIVGPDEQGAMFSFSASVEATCILIAATIFNG 419

Query: 378 IYMSTIETFPGAFYLFDAALTVVALCL 458
           +Y  T+ TFPG  ++  AA  ++ L L
Sbjct: 420 LYPLTLPTFPGMPFIIMAAFMLIVLIL 446


>UniRef50_Q16TG3 Cluster: Putative uncharacterized protein; n=1;
           Aedes aegypti|Rep: Putative uncharacterized protein -
           Aedes aegypti (Yellowfever mosquito)
          Length = 507

 Score = 40.3 bits (90), Expect = 0.025
 Identities = 28/87 (32%), Positives = 48/87 (55%), Gaps = 3/87 (3%)
 Frame = +3

Query: 63  NIVVGLLGTIFCILVLSKRMNVQDSIIGALA-GVSRIAGCLMFALAPTRQ--WFYSAPLF 233
           +++  LLGT+  + VLSKR+ V D +I   +   + IA  +M   A + Q   +Y A   
Sbjct: 222 DLMTTLLGTLLAMGVLSKRLGVSDFLICVFSVCFTLIAKPIMAYAASSVQPYLYYVATSI 281

Query: 234 NIFSFTGLTAIRSIATKSVPTEEVAKL 314
           ++F  + + AIRSI +K V   E+ ++
Sbjct: 282 DVFEGSKIVAIRSIVSKLVEQNEIGEV 308


>UniRef50_Q9BY10 Cluster: Thymic stromal cotransporter homolog;
           n=16; Amniota|Rep: Thymic stromal cotransporter homolog
           - Homo sapiens (Human)
          Length = 475

 Score = 40.3 bits (90), Expect = 0.025
 Identities = 31/143 (21%), Positives = 65/143 (45%)
 Frame = +3

Query: 24  GFTEVEYSIYGTINIVVGLLGTIFCILVLSKRMNVQDSIIGALAGVSRIAGCLMFALAPT 203
           G+ +V+   YG        + +   +LV S+    +D+ +  +  VS  +G L+ A    
Sbjct: 314 GWNQVQVG-YGMAAGYTIFITSFLGVLVFSRCF--RDTTMIMIGMVSFGSGALLLAFVKE 370

Query: 204 RQWFYSAPLFNIFSFTGLTAIRSIATKSVPTEEVAKLSALMGVTESLAPSIYMPASSYIY 383
              FY A    +F+   +T IRS  +K +      K+  ++ ++ +L   +     + IY
Sbjct: 371 TYMFYIARAVMLFALIPVTTIRSAMSKLIKGSSYGKVFVILQLSLALTGVVTSTLYNKIY 430

Query: 384 MSTIETFPGAFYLFDAALTVVAL 452
             T++ F G+ +   + L+ +A+
Sbjct: 431 QLTMDMFVGSCFALSSFLSFLAI 453


>UniRef50_A0B668 Cluster: Drug resistance transporter, Bcr/CflA
           subfamily; n=3; Euryarchaeota|Rep: Drug resistance
           transporter, Bcr/CflA subfamily - Methanosaeta
           thermophila (strain DSM 6194 / PT)
           (Methanothrixthermophila (strain DSM 6194 / PT))
          Length = 422

 Score = 39.9 bits (89), Expect = 0.034
 Identities = 37/145 (25%), Positives = 63/145 (43%), Gaps = 3/145 (2%)
 Frame = +3

Query: 21  FGFTEVEYSIYGTINIVVGLLGTIFCILVLSKRMNVQDSIIGALAGVSRIAGCLMFALAP 200
           FG +E+EYS +   N  +G++ +    L LS+RM  + S +    GV  ++G L+  L  
Sbjct: 259 FGLSELEYSYFFAFN-AIGMISSPTIYLKLSRRM-CRRSFVTMCFGVMILSGTLILILGT 316

Query: 201 TRQWFYSAPLFNIFSFTGLTAIRSIATKSV---PTEEVAKLSALMGVTESLAPSIYMPAS 371
              W ++  L  + S     A+R+  T  +     E+    +ALM     +A SI M   
Sbjct: 317 WSPWIFAVAL--LPSTIAAGAVRTPGTNLMLEQQREDTGSAAALMSCFGIIAGSIGMTLI 374

Query: 372 SYIYMSTIETFPGAFYLFDAALTVV 446
           S    + I    G  Y+    +  +
Sbjct: 375 SMTRENMIPAL-GMMYMLIGTICAI 398


>UniRef50_Q56RY7 Cluster: TetA; n=4; Acinetobacter|Rep: TetA -
           Acinetobacter sp. LUH5605
          Length = 395

 Score = 35.9 bits (79), Expect = 0.55
 Identities = 26/95 (27%), Positives = 43/95 (45%), Gaps = 2/95 (2%)
 Frame = +3

Query: 51  YGTINIVVGLLGTIFCILV--LSKRMNVQDSIIGALAGVSRIAGCLMFALAPTRQWFYSA 224
           YG +  V  L+  IF  ++  LS R   +  +I ++AG +  A  L+ A AP+  W Y  
Sbjct: 43  YGALLAVYALMQFIFAPILGALSDRFGRRPVLIISIAGAT--ADYLLMAAAPSLLWLYIG 100

Query: 225 PLFNIFSFTGLTAIRSIATKSVPTEEVAKLSALMG 329
            +F   +   +    +  +   P  E AK   L+G
Sbjct: 101 RIFAGITGANMAVATAYVSDITPAHERAKRFGLLG 135


>UniRef50_Q1CWB1 Cluster: Putative lipoprotein; n=1; Myxococcus
           xanthus DK 1622|Rep: Putative lipoprotein - Myxococcus
           xanthus (strain DK 1622)
          Length = 649

 Score = 35.9 bits (79), Expect = 0.55
 Identities = 21/78 (26%), Positives = 34/78 (43%)
 Frame = +3

Query: 219 SAPLFNIFSFTGLTAIRSIATKSVPTEEVAKLSALMGVTESLAPSIYMPASSYIYMSTIE 398
           +AP F   S T LT +    ++++    +        +TESL  S +      ++++T E
Sbjct: 338 AAPTFESASATSLTELVLSFSRNISAASITNAPEQFTLTESLTVSAFRVEGKQVFLTTSE 397

Query: 399 TFPGAFYLFDAALTVVAL 452
             PG  Y    A TV  L
Sbjct: 398 QTPGTNYSVTVANTVTDL 415


>UniRef50_A7RHU0 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 515

 Score = 35.9 bits (79), Expect = 0.55
 Identities = 28/128 (21%), Positives = 57/128 (44%), Gaps = 1/128 (0%)
 Frame = +3

Query: 75  GLLGTIFCILVLSKRMNVQDSIIGALAGVSRIAGCLMFALAPTRQWFYSAPLFNIFSFTG 254
           G LG    I +L K +N  + +   +  +S ++G L+FA +      +  P  +      
Sbjct: 340 GGLGGAVMISLLKKCLNELNIV--RVGYISVMSGLLLFAFSDRTWMVFLGPAVSFARGVT 397

Query: 255 LTAIRSIATKSVPTEEVAKLSALMGVTESLAPSIYMPASSYIY-MSTIETFPGAFYLFDA 431
                 +++K V  ++   L A++G+  ++   +     + IY MS    FPG  ++  A
Sbjct: 398 DPIFLDMSSKIVSQDDQGSLFAVVGILSTIGELVGTSLFNNIYPMSLRFGFPGLVFVISA 457

Query: 432 ALTVVALC 455
            + ++ LC
Sbjct: 458 GIFLIILC 465


>UniRef50_UPI0000584089 Cluster: PREDICTED: similar to MGC80576
           protein; n=1; Strongylocentrotus purpuratus|Rep:
           PREDICTED: similar to MGC80576 protein -
           Strongylocentrotus purpuratus
          Length = 496

 Score = 35.5 bits (78), Expect = 0.72
 Identities = 29/146 (19%), Positives = 59/146 (40%)
 Frame = +3

Query: 21  FGFTEVEYSIYGTINIVVGLLGTIFCILVLSKRMNVQDSIIGALAGVSRIAGCLMFALAP 200
           F +T ++   Y  +++++  +G++     +    N  D  +  ++ +S +A C   ALA 
Sbjct: 349 FCWTPIDVGFYTAVSLILPGVGSLVGGQFVYHFNN--DYWMMHISLISAMAMCFTTALAK 406

Query: 201 TRQWFYSAPLFNIFSFTGLTAIRSIATKSVPTEEVAKLSALMGVTESLAPSIYMPASSYI 380
           T    YS  +    S      IR + +K V   E   +    G   +    I    +  I
Sbjct: 407 TTPVLYSGLVVGAMSSFIAPLIRGLMSKMVGEHEQVSVFTYAGCVGNTVKFIAKVMAFSI 466

Query: 381 YMSTIETFPGAFYLFDAALTVVALCL 458
           Y  T+ T P   +     + ++ +C+
Sbjct: 467 YAGTVHTLPTLTFYVLGFIVIIPICI 492


>UniRef50_A7RIK2 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 262

 Score = 35.5 bits (78), Expect = 0.72
 Identities = 28/88 (31%), Positives = 44/88 (50%), Gaps = 3/88 (3%)
 Frame = +3

Query: 198 PTRQWFYSAPLFNIFSFTGLTAIRSIATKSVPTEEVAKLSALMGVTESLAPSIYMPASSY 377
           P++  F   PL +  S   L +++ + +K VPTEE   L   +   E+LA        + 
Sbjct: 143 PSQIAFRLVPLISALSGPLLPSVKGMMSKMVPTEEQGSLFTGVSAVETLARIFGAAVVNA 202

Query: 378 IYMSTIET-FPG-AFYLFDAALTV-VAL 452
           IY+ +I+   PG AF+    AL + VAL
Sbjct: 203 IYVRSIDVGMPGIAFWACAVALLIPVAL 230


>UniRef50_A4FEN1 Cluster: Multidrug transporter; n=1;
           Saccharopolyspora erythraea NRRL 2338|Rep: Multidrug
           transporter - Saccharopolyspora erythraea (strain NRRL
           23338)
          Length = 467

 Score = 35.1 bits (77), Expect = 0.96
 Identities = 32/122 (26%), Positives = 48/122 (39%), Gaps = 7/122 (5%)
 Frame = +3

Query: 150 LAGVSRIAGCLMFALAPTRQWFYSAPLFNI-FSFTG--LTAIRSIATKSVPTEEVAKLSA 320
           +  V   A  +   L P   W   A L  +  ++TG  LTA+  +A  S P ++   L  
Sbjct: 346 IGAVGTAAAFVPLVLLPQSPWVACAALAALGITYTGYSLTALNGLAVASAPADKPGSLPG 405

Query: 321 LMGVTESLAPSIYMPASSYIYMSTIETFPGAFYLFDAAL----TVVALCLFGMIYILARK 488
           L G    +  S+ +  SS +  +     P     F AAL      VAL L   + I    
Sbjct: 406 LNGACFGVGASLGIAVSSSVVTAATAGGPPTAGAFQAALWSSAVFVALALLTALLIRPAT 465

Query: 489 KN 494
           +N
Sbjct: 466 EN 467


>UniRef50_UPI00015B4C6B Cluster: PREDICTED: similar to
           sodium-dependent phosphate transporter; n=1; Nasonia
           vitripennis|Rep: PREDICTED: similar to sodium-dependent
           phosphate transporter - Nasonia vitripennis
          Length = 470

 Score = 34.7 bits (76), Expect = 1.3
 Identities = 18/75 (24%), Positives = 38/75 (50%)
 Frame = +3

Query: 237 IFSFTGLTAIRSIATKSVPTEEVAKLSALMGVTESLAPSIYMPASSYIYMSTIETFPGAF 416
           +F    L++I ++ +K  P  E +++S  +    +L   + M  S  I  S +  +PG F
Sbjct: 131 VFQACYLSSIHTLTSKWAPPHERSRISTFITAGATLGNVVAMALSGVIAASNLG-WPGVF 189

Query: 417 YLFDAALTVVALCLF 461
           Y+F  A  ++++  +
Sbjct: 190 YVFGIANIIMSIAFY 204


>UniRef50_Q6BW37 Cluster: Similar to CA5023|IPF7547 Candida albicans
           IPF7547 of unknown function; n=2;
           Saccharomycetaceae|Rep: Similar to CA5023|IPF7547
           Candida albicans IPF7547 of unknown function -
           Debaryomyces hansenii (Yeast) (Torulaspora hansenii)
          Length = 623

 Score = 34.7 bits (76), Expect = 1.3
 Identities = 30/138 (21%), Positives = 54/138 (39%), Gaps = 2/138 (1%)
 Frame = +3

Query: 105 VLSKRMNVQDSIIGALAGVSRIAGCLMFALAPTRQWFYSAPLFNIFSFTGLTAIRSIATK 284
           VL  + ++ D  +  +       G  + +LAP+  WF        F      ++ S   K
Sbjct: 438 VLKSQFDMVDLGVCVIGLSLEAVGLALLSLAPSTTWFLIGMSIMSFGALASPSLNSAIIK 497

Query: 285 SVPTEEVAKLSALMGVTESLAPSIYMPASSYIYMSTIETF--PGAFYLFDAALTVVALCL 458
             P  ++ +L   M + +++           IY  ++  +  PG  +LF +      L L
Sbjct: 498 FYPESKIGELFGAMSLLKNMFTLAGPVTFLSIYKVSLSRWNAPGTVFLFSS-----MLML 552

Query: 459 FGMIYILARKKNIALSAN 512
           F  + IL  KK + L  N
Sbjct: 553 FSTVLILVVKKLLNLDKN 570


>UniRef50_A4QNU5 Cluster: Cxcr3.1 protein; n=9; Clupeocephala|Rep:
           Cxcr3.1 protein - Danio rerio (Zebrafish) (Brachydanio
           rerio)
          Length = 357

 Score = 34.3 bits (75), Expect = 1.7
 Identities = 24/81 (29%), Positives = 39/81 (48%), Gaps = 5/81 (6%)
 Frame = +3

Query: 3   CTQ*GKFGFTEVEYSIYGTINIVVGLLGTIFCILVLSKR---MNVQDSII--GALAGVSR 167
           CTQ     F  +   I  ++  VVGLLG    ++VL K+   +NV D  I   +LA +  
Sbjct: 28  CTQDSSMYFDSIFKPILYSLAAVVGLLGNGLVLIVLWKKRAGLNVTDIFILHLSLADILL 87

Query: 168 IAGCLMFALAPTRQWFYSAPL 230
           +     +A+   ++W +  PL
Sbjct: 88  LLTLPFWAVEAVKEWIFGTPL 108


>UniRef50_Q46MT8 Cluster: Major facilitator superfamily MFS_1; n=1;
           Ralstonia eutropha JMP134|Rep: Major facilitator
           superfamily MFS_1 - Ralstonia eutropha (strain JMP134)
           (Alcaligenes eutrophus)
          Length = 450

 Score = 34.3 bits (75), Expect = 1.7
 Identities = 38/153 (24%), Positives = 66/153 (43%), Gaps = 11/153 (7%)
 Frame = +3

Query: 48  IYGTINIVVGLLGTIFCILVLSKRMNVQDSIIGALAG--VSRIAGCL--MFALA--PTRQ 209
           I G + + +G LG     L +  R         AL G  VS    CL  M  +A  P+  
Sbjct: 277 IQGGLLLTMGPLGLWLAGLAMDARACANRLSGVALVGMVVSIAVPCLGVMLCVAGTPSAF 336

Query: 210 WFYSAPLFNIFSFTGLTAIRSIATKSVPTEEVAKLSALMGVT-----ESLAPSIYMPASS 374
           W   A +  +FS+T +    +I  ++VPT  V  + A++ V      + L+P++   A  
Sbjct: 337 WLLDAMVV-LFSWTFMAVTSTIVARTVPTTAVGLVMAIVLVLNGLIGQGLSPTLIALAGK 395

Query: 375 YIYMSTIETFPGAFYLFDAALTVVALCLFGMIY 473
           +++ +  +       L  A   V+A+   G +Y
Sbjct: 396 HVFDARSDALAHGMALVFACAGVLAVAASGWMY 428


>UniRef50_A5G2L8 Cluster: Major facilitator superfamily MFS_1; n=1;
           Acidiphilium cryptum JF-5|Rep: Major facilitator
           superfamily MFS_1 - Acidiphilium cryptum (strain JF-5)
          Length = 405

 Score = 34.3 bits (75), Expect = 1.7
 Identities = 22/101 (21%), Positives = 43/101 (42%), Gaps = 5/101 (4%)
 Frame = +3

Query: 171 AGCLMFALAPTRQWFYSAPLFNIFSFTGLTAIRSIATKSVPTEEVAKLSALMGVTESLAP 350
           A  ++F +APT  W ++             AIRS+ +++ P ++  +++  +   E L  
Sbjct: 286 AAYMIFGVAPTASWLFAGVGLMALGSIANPAIRSMLSRAAPADQQGRMNGALSSIEGLT- 344

Query: 351 SIYMPASSYIYMSTIE-----TFPGAFYLFDAALTVVALCL 458
           +I  P +  +            FPGA ++  A +   A  L
Sbjct: 345 AIVAPLTGAVVFEAFSGVLPWRFPGAPFVMVAVMLAGAAML 385


>UniRef50_A4FJA9 Cluster: Transporter, MFS superfamily; n=1;
           Saccharopolyspora erythraea NRRL 2338|Rep: Transporter,
           MFS superfamily - Saccharopolyspora erythraea (strain
           NRRL 23338)
          Length = 400

 Score = 34.3 bits (75), Expect = 1.7
 Identities = 34/142 (23%), Positives = 62/142 (43%)
 Frame = +3

Query: 24  GFTEVEYSIYGTINIVVGLLGTIFCILVLSKRMNVQDSIIGALAGVSRIAGCLMFALAPT 203
           G   V Y+ Y     +VGLLG +    + S R+  +  ++ AL  +  +A CL+FA A T
Sbjct: 50  GVVTVVYAAY-----IVGLLGALMVAGIASDRLGRKPILLPALL-LGALA-CLLFATATT 102

Query: 204 RQWFYSAPLFNIFSFTGLTAIRSIATKSVPTEEVAKLSALMGVTESLAPSIYMPASSYIY 383
                 A L    +   + +  + A   V     ++L++L+G T  +  +   P  + + 
Sbjct: 103 VPTLVLARLLTGIAVGAILSAGTAAVSDVAGPRRSRLASLLGSTAMVLGAGLGPLLAGVL 162

Query: 384 MSTIETFPGAFYLFDAALTVVA 449
             T+     A ++  AA+   A
Sbjct: 163 SETLPGPTVAVFVLVAAVLATA 184


>UniRef50_A6G6F6 Cluster: NADH dehydrogenase; n=1; Plesiocystis
           pacifica SIR-1|Rep: NADH dehydrogenase - Plesiocystis
           pacifica SIR-1
          Length = 533

 Score = 33.9 bits (74), Expect = 2.2
 Identities = 23/110 (20%), Positives = 49/110 (44%), Gaps = 4/110 (3%)
 Frame = +3

Query: 162 SRIAGCLMFALAPTRQWFYSAPLFNIFSFTGLTAIRS--IATKSVPTEEVAKLSALMGVT 335
           +R   C   ++A      +SA +F +F F    ++ +  + T     E +      +G+ 
Sbjct: 132 TRFYVCFALSIASVMGIAFSANMFTLFIFYEALSLATFPLVTHKGTKEALRSGRTYLGIL 191

Query: 336 ESLAPSIYMPA--SSYIYMSTIETFPGAFYLFDAALTVVALCLFGMIYIL 479
              +  + +PA  ++Y+Y  T++   G  +    A  V+   LFG+I+ +
Sbjct: 192 MGTSVCLMLPAMVATYVYCGTLDFTQGGVFAQPLADGVLTPALFGIIFAM 241


>UniRef50_O13714 Cluster: Uncharacterized membrane protein C14C4.07;
           n=1; Schizosaccharomyces pombe|Rep: Uncharacterized
           membrane protein C14C4.07 - Schizosaccharomyces pombe
           (Fission yeast)
          Length = 644

 Score = 33.9 bits (74), Expect = 2.2
 Identities = 22/105 (20%), Positives = 52/105 (49%), Gaps = 1/105 (0%)
 Frame = +3

Query: 168 IAGCLMFALAPTRQWFYSAPLFNIFSFTGLTAIRSIATKSVPTEEVAKLSALMGVTESLA 347
           ++  ++ A+A +    ++A +    S   +  ++SIA   V +E   ++ A   V E++A
Sbjct: 533 LSAAVLLAVAKSDVALFTAVIIQAISNMVVPCVQSIALNGVQSEYNGRVLAAFAVFEAVA 592

Query: 348 PSIYMPASSYIYMSTIE-TFPGAFYLFDAALTVVALCLFGMIYIL 479
             I  P  +++Y  +++ ++P   +   A   V+  C F +I+ +
Sbjct: 593 LIIRGPIYAFVYTESMKVSYPNMIFFLSA---VIYGCCFIIIFFM 634


>UniRef50_Q6N424 Cluster: Possible bcr efflux pump, Major
           Facilitator Superfamily; n=8; Bradyrhizobiaceae|Rep:
           Possible bcr efflux pump, Major Facilitator Superfamily
           - Rhodopseudomonas palustris
          Length = 428

 Score = 33.5 bits (73), Expect = 2.9
 Identities = 38/167 (22%), Positives = 70/167 (41%), Gaps = 6/167 (3%)
 Frame = +3

Query: 18  KFGFTEVEYSIYGTINIVVGLLGTIFCILVLSKRMNVQDSIIGALAGVSRIAGCLM---F 188
           + G +  EY  +   +    L+G +FC+   S R ++ D +I    G+ +IAG L+   +
Sbjct: 255 QMGRSSAEYGAWFASSGFAYLMGNVFCVK-FSPRHSL-DRLIWFGLGL-QIAGALLNLAW 311

Query: 189 ALAPTRQ---WFYSAPLFNIFSFTGLTAIRSIATKSVPTEEVAKLSALMGVTESLAPSIY 359
            +    Q   W +   +  +F    + A  +    S+  +     S LMG T+    S+ 
Sbjct: 312 GILGWNQVPSWLFGTHMIIMFGNAAVMANAAAGAISIRPQAAGTASGLMGFTQFGFGSLC 371

Query: 360 MPASSYIYMSTIETFPGAFYLFDAALTVVALCLFGMIYILARKKNIA 500
             A +++        P    +F  AL     C   MI+++ R+  IA
Sbjct: 372 SQAGAWLGGHFATPLPLNIAIFGTALA----CASAMIFLVPRRNLIA 414


>UniRef50_A7RIS8 Cluster: Predicted protein; n=2; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 509

 Score = 33.5 bits (73), Expect = 2.9
 Identities = 34/156 (21%), Positives = 65/156 (41%), Gaps = 13/156 (8%)
 Frame = +3

Query: 42  YSIYGTINIVVGLLGTIFCI--------LVLSKRMNVQDSIIGALAGVSRIAGCLMFALA 197
           Y +  +  +V   LGT+ C+        + L   M + +     +  +  IAG  M   +
Sbjct: 295 YPLCWSAELVGYFLGTLLCVKAFGAVLGIWLGSLMKLTNYTAAQIGTLFLIAGLTMIGFS 354

Query: 198 PTRQWFYSAPLFNIFSFTGLTAIRSIATKSVPTEEVAKLSALMGVTESL----APSIYMP 365
            T    + + + N+FS      IR+  ++ V  EE   L A++   ESL    +  I+ P
Sbjct: 355 QTTFLMFMSCVANLFSGVPQPCIRAQMSQMVGKEEQGALFAILASLESLTNFTSQLIFNP 414

Query: 366 ASSYIYMSTIETF-PGAFYLFDAALTVVALCLFGMI 470
             ++   +    +  G  +  +A + V+   L G+I
Sbjct: 415 LYAWSIANVAWKYAAGIPFFVNAGIAVIPFILLGVI 450


>UniRef50_Q4WVN5 Cluster: MFS multidrug transporter, putative; n=1;
           Aspergillus fumigatus|Rep: MFS multidrug transporter,
           putative - Aspergillus fumigatus (Sartorya fumigata)
          Length = 478

 Score = 33.5 bits (73), Expect = 2.9
 Identities = 22/98 (22%), Positives = 48/98 (48%), Gaps = 2/98 (2%)
 Frame = +3

Query: 57  TINIVVGLLGTIFCILVLSKRMNV--QDSIIGALAGVSRIAGCLMFALAPTRQWFYSAPL 230
           T+ + + L+  +  +L  +  ++   +D  +  L+G+   AG  M ALA   +W+ +  +
Sbjct: 315 TLAVYLVLMPALSGVLTATTSLSAMQKDRRMAQLSGILSAAGLGMVALAAIPEWYVAGLV 374

Query: 231 FNIFSFTGLTAIRSIATKSVPTEEVAKLSALMGVTESL 344
            +      +   RS+AT+ V   + + L A + V +S+
Sbjct: 375 ISALGAGFIVFARSLATQLVTPAQRSTLYAAVAVVQSV 412


>UniRef50_Q07282 Cluster: Tetracycline resistance protein, class E
           (TetA(E)); n=85; root|Rep: Tetracycline resistance
           protein, class E (TetA(E)) - Escherichia coli
          Length = 405

 Score = 33.5 bits (73), Expect = 2.9
 Identities = 29/98 (29%), Positives = 47/98 (47%), Gaps = 3/98 (3%)
 Frame = +3

Query: 174 GCLMFALAPTRQWFYSAPLFNIFSFTGLTAIRSIATKSVPTEEVAKLSALMGVTESLA-- 347
           GC +F LA   Q +   P+  + +  G+T        SV   +VA+   L GV  SL   
Sbjct: 287 GCGLFLLAVITQSWMVWPVLLLLACGGITLPALQGIISVRVGQVAQ-GQLQGVLTSLTHL 345

Query: 348 PSIYMP-ASSYIYMSTIETFPGAFYLFDAALTVVALCL 458
            ++  P   +++Y +T ET+ G  ++    L VVAL +
Sbjct: 346 TAVIGPLVFAFLYSATRETWNGWVWIIGCGLYVVALII 383


>UniRef50_Q8ENR4 Cluster: Hypothetical conserved protein; n=1;
           Oceanobacillus iheyensis|Rep: Hypothetical conserved
           protein - Oceanobacillus iheyensis
          Length = 366

 Score = 33.1 bits (72), Expect = 3.9
 Identities = 20/53 (37%), Positives = 25/53 (47%), Gaps = 3/53 (5%)
 Frame = +3

Query: 357 YMPASSYIYMSTIETFPGAFYLFDAAL---TVVALCLFGMIYILARKKNIALS 506
           Y P  S  Y  ++E    A    D+ L    +  LCL G +YI   KKN ALS
Sbjct: 292 YAPLLSMFYDGSLEGSKVALIATDSGLFLGAIAFLCLLGSLYIFKIKKNAALS 344


>UniRef50_A6GGP3 Cluster: Response regulator; n=1; Plesiocystis
           pacifica SIR-1|Rep: Response regulator - Plesiocystis
           pacifica SIR-1
          Length = 372

 Score = 33.1 bits (72), Expect = 3.9
 Identities = 22/72 (30%), Positives = 37/72 (51%)
 Frame = -3

Query: 328 PISALSLATSSVGTLLVAIDLIAVRPVKLKMLNRGAE*NHCLVGARANMRHPAILLTPAK 149
           PI+ L L   SVG  +   D +  R +++++   G      +  A A  R P I+L+  +
Sbjct: 121 PINLL-LVDDSVGVRIELGDALRDRGLRVRVAENGL-----VAIAAALKRPPDIILSDVE 174

Query: 148 APIMLSWTFIRL 113
            P+M  WTF+R+
Sbjct: 175 MPVMDGWTFLRM 186


>UniRef50_Q9TAK8 Cluster: NADH-ubiquinone oxidoreductase chain 4;
           n=1; Cafeteria roenbergensis|Rep: NADH-ubiquinone
           oxidoreductase chain 4 - Cafeteria roenbergensis
          Length = 453

 Score = 33.1 bits (72), Expect = 3.9
 Identities = 27/79 (34%), Positives = 36/79 (45%), Gaps = 11/79 (13%)
 Frame = +3

Query: 216 YSAPLFNIFS-----FTGLTAIRSIATK------SVPTEEVAKLSALMGVTESLAPSIYM 362
           Y +PL N+F+     FT +TAIR I  K      S+    V  L  L+   ESL  +I+ 
Sbjct: 239 YFSPLINVFALISIVFTSMTAIRQIDLKKIIAYSSIGHMNVVLLGMLVPSVESLEGTIFQ 298

Query: 363 PASSYIYMSTIETFPGAFY 419
             S  I    +    GAFY
Sbjct: 299 MLSHGIIAGALFFIVGAFY 317


>UniRef50_Q8TPP8 Cluster: Membrane transport protein; n=3;
           Methanosarcina|Rep: Membrane transport protein -
           Methanosarcina acetivorans
          Length = 416

 Score = 33.1 bits (72), Expect = 3.9
 Identities = 20/80 (25%), Positives = 38/80 (47%)
 Frame = +3

Query: 21  FGFTEVEYSIYGTINIVVGLLGTIFCILVLSKRMNVQDSIIGALAGVSRIAGCLMFALAP 200
           FG TE +YS +   N +  ++G+  C L L++ +  +  +    AG+  + G  +     
Sbjct: 263 FGMTEQKYSYFFAFNAMALMVGSFSC-LRLTRSIRSKHLMTVGFAGIF-LGGIFLLFTGQ 320

Query: 201 TRQWFYSAPLFNIFSFTGLT 260
              W ++ P+F I    GL+
Sbjct: 321 HGPWSFALPMFLITFSLGLS 340


>UniRef50_P13090 Cluster: Aminotriazole resistance protein; n=12;
           Saccharomycetales|Rep: Aminotriazole resistance protein
           - Saccharomyces cerevisiae (Baker's yeast)
          Length = 542

 Score = 33.1 bits (72), Expect = 3.9
 Identities = 21/79 (26%), Positives = 39/79 (49%), Gaps = 3/79 (3%)
 Frame = +3

Query: 69  VVGLLGTIFCILVLSKRMNVQDSIIGALAGVSRIAGCLMFALAPT---RQWFYSAPLFNI 239
           V+G++G I+  +  + R N+  S +GA+A +    GCL   L  T   +QW ++   ++I
Sbjct: 182 VLGIIGNIY--VGGTFRKNIVISFVGAMAPIGATLGCLFAGLIGTEDPKQWPWAFYAYSI 239

Query: 240 FSFTGLTAIRSIATKSVPT 296
            +F            ++PT
Sbjct: 240 AAFINFVLSIYAIPSTIPT 258


>UniRef50_Q0EZ29 Cluster: Colicin V production protein; n=1;
           Mariprofundus ferrooxydans PV-1|Rep: Colicin V
           production protein - Mariprofundus ferrooxydans PV-1
          Length = 183

 Score = 32.7 bits (71), Expect = 5.1
 Identities = 20/60 (33%), Positives = 29/60 (48%)
 Frame = +3

Query: 48  IYGTINIVVGLLGTIFCILVLSKRMNVQDSIIGALAGVSRIAGCLMFALAPTRQWFYSAP 227
           I+  + IVVGL+G + C LV    +   D  +G   G +R  G L+ AL       Y+ P
Sbjct: 55  IFIVVMIVVGLIGALICRLVDLAALTATDRTLGIFFGAAR--GMLLIALCFLVYTSYTKP 112


>UniRef50_A7RP47 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 378

 Score = 32.7 bits (71), Expect = 5.1
 Identities = 21/74 (28%), Positives = 37/74 (50%), Gaps = 2/74 (2%)
 Frame = +3

Query: 141 IGALAGVSRIAGCLMFALAPTRQWFYSAPLFNIFSFTGLTAIRSIATKSVPTEE--VAKL 314
           +GA+ G+S +  C++F  +  R   Y   + +  +      IR IA K +PT+   V  +
Sbjct: 124 VGAVYGLSAV--CIVFGASGERTAPYLQSILSTANIPATLLIRFIALKKIPTKRKFVCAI 181

Query: 315 SALMGVTESLAPSI 356
             L+ ++  L PSI
Sbjct: 182 VTLLSLSLCLMPSI 195


>UniRef50_UPI00006CFE81 Cluster: major facilitator superfamily
           protein; n=1; Tetrahymena thermophila SB210|Rep: major
           facilitator superfamily protein - Tetrahymena
           thermophila SB210
          Length = 480

 Score = 32.3 bits (70), Expect = 6.8
 Identities = 18/52 (34%), Positives = 29/52 (55%)
 Frame = +3

Query: 39  EYSIYGTINIVVGLLGTIFCILVLSKRMNVQDSIIGALAGVSRIAGCLMFAL 194
           +Y I  + + +V L G I C++++SK   +   II   A   +IAGCL+  L
Sbjct: 72  KYLINSSFSGMVPLGGCIGCLIIISKVFRIGRRIILIFADFIQIAGCLISIL 123


>UniRef50_Q4JVV2 Cluster: Putative membrane protein precursor; n=1;
           Corynebacterium jeikeium K411|Rep: Putative membrane
           protein precursor - Corynebacterium jeikeium (strain
           K411)
          Length = 437

 Score = 32.3 bits (70), Expect = 6.8
 Identities = 20/73 (27%), Positives = 34/73 (46%)
 Frame = +3

Query: 66  IVVGLLGTIFCILVLSKRMNVQDSIIGALAGVSRIAGCLMFALAPTRQWFYSAPLFNIFS 245
           + V  +  ++ I+VL        S+I AL GV     C++   +    W +  PLF +F 
Sbjct: 277 VCVVAIVVLYSIVVLGCYRRGNYSMIMALGGV---VACIISPFSWYHHWVFLVPLFVVFL 333

Query: 246 FTGLTAIRSIATK 284
             G   ++SI+ K
Sbjct: 334 DAGFQLVQSISNK 346


>UniRef50_Q0TI71 Cluster: Probable drug transport transmembrane
           protein; n=10; Enterobacteriaceae|Rep: Probable drug
           transport transmembrane protein - Escherichia coli
           O6:K15:H31 (strain 536 / UPEC)
          Length = 387

 Score = 32.3 bits (70), Expect = 6.8
 Identities = 31/122 (25%), Positives = 58/122 (47%), Gaps = 4/122 (3%)
 Frame = +3

Query: 18  KFGFTEVEYSIYGTINIVVGLLGTIFCILVLSKRMNVQDSIIGALAGVSRIAGCLMFALA 197
           +FGF+ +++S+   +N  +GL+   +    L++R+N    + G L  ++ I   L+  L 
Sbjct: 236 EFGFSPMQFSLVFGLN-GIGLIIASWIFSRLARRINAMTLLRGGL--IAAILCALLTVLC 292

Query: 198 PTRQWFYSAPLFNIFSFTGLTAIRSI----ATKSVPTEEVAKLSALMGVTESLAPSIYMP 365
              Q    A +   F+    + I ++    A  +V T+E    SALMG++  +   I  P
Sbjct: 293 AWVQLPIPALVALFFTIAFCSGIGTVGGAEAMSAVGTQESGTASALMGMSMFVFGGIAAP 352

Query: 366 AS 371
            S
Sbjct: 353 LS 354


>UniRef50_Q0BZH6 Cluster: Putative membrane protein; n=1; Hyphomonas
           neptunium ATCC 15444|Rep: Putative membrane protein -
           Hyphomonas neptunium (strain ATCC 15444)
          Length = 474

 Score = 32.3 bits (70), Expect = 6.8
 Identities = 43/170 (25%), Positives = 74/170 (43%), Gaps = 15/170 (8%)
 Frame = +3

Query: 15  GKFGFTEVEYSIYGTINIVVGLLGTIFCILV---LSKRMNVQDSIIGALAGVSRIAGC-- 179
           G  G+   E  +YG +  V GL+G +    +      R+  Q  I G++ G+  I G   
Sbjct: 291 GVMGWAGTEMLVYGLLGCVAGLIGGVLAGWLDETFGPRIAFQIEIAGSVIGLIGIIGAAP 350

Query: 180 --LMFALAPTRQWFYSAPLFN-----IFSFTG-LTAIRSIATKSVPTEEVAKL--SALMG 329
             ++F      Q  ++AP+F      +F F G L  +  IA  S     + +L  ++ MG
Sbjct: 351 AQILFMPVADPQPIWNAPMFTTLPELVFVFFGFLGFVFQIAAWSSSRTLLTRLAPASQMG 410

Query: 330 VTESLAPSIYMPASSYIYMSTIETFPGAFYLFDAALTVVALCLFGMIYIL 479
               LA ++   ++S++    +  F   F+   A    VA+ LF   +IL
Sbjct: 411 AFFGLA-ALAGNSTSWLGPMFVGIFTAVFHSQQAGFIPVAV-LFAAGFIL 458


>UniRef50_Q7SFA1 Cluster: Predicted protein; n=1; Neurospora
           crassa|Rep: Predicted protein - Neurospora crassa
          Length = 589

 Score = 32.3 bits (70), Expect = 6.8
 Identities = 29/96 (30%), Positives = 46/96 (47%), Gaps = 2/96 (2%)
 Frame = +3

Query: 84  GTIFCILVLSKRMNVQDSI-IGALAGVSRIAGCLMFALAPTRQWFYSAP-LFNIFSFTGL 257
           GT F  L L+    +Q  + +   + +    GCL+ ALA TR  F S   LF + S  G 
Sbjct: 427 GTHFYHLNLTPLTPLQKDLHLARASSLLLTLGCLLIALATTRLGFTSGMILFALGSGLGS 486

Query: 258 TAIRSIATKSVPTEEVAKLSALMGVTESLAPSIYMP 365
           T +RS+    V  E +  L++++G  E +   +  P
Sbjct: 487 T-LRSLLNALVDEEHMGLLNSVVGWLEMVGIMVAGP 521


>UniRef50_Q2UHN6 Cluster: Predicted protein; n=1; Aspergillus
           oryzae|Rep: Predicted protein - Aspergillus oryzae
          Length = 422

 Score = 32.3 bits (70), Expect = 6.8
 Identities = 18/55 (32%), Positives = 29/55 (52%)
 Frame = +2

Query: 98  YISAQQTNECPRQHYRRFSGSEQDSRMPHVRPCSDQTMVLFRSSIQHLQFYWSDS 262
           ++ AQ+  +  R+H RR +  +  SR    R C  Q + + R SI+ L  Y SD+
Sbjct: 337 WLDAQRKADSLRRHPRRMNAGDITSRTTLGRHCELQAICMKRPSIELLSSYSSDT 391


>UniRef50_UPI00006A1D1F Cluster: Protein SAAL1.; n=1; Xenopus
           tropicalis|Rep: Protein SAAL1. - Xenopus tropicalis
          Length = 460

 Score = 31.9 bits (69), Expect = 8.9
 Identities = 23/65 (35%), Positives = 29/65 (44%), Gaps = 2/65 (3%)
 Frame = +3

Query: 177 CLMFALAPTRQW--FYSAPLFNIFSFTGLTAIRSIATKSVPTEEVAKLSALMGVTESLAP 350
           CL F   PT  W    SA LF      G   + +IA +  P      L+A +GV+   AP
Sbjct: 181 CLAFC-PPTGAWGTIGSAELFFFLHHAGKGIMLAIAQQRHPQRASRLLTARLGVSLLTAP 239

Query: 351 SIYMP 365
            IY P
Sbjct: 240 RIYFP 244


>UniRef50_UPI000065EFC5 Cluster: Protein FAM5C precursor
           (DBCCR1-like protein 1).; n=2; Takifugu rubripes|Rep:
           Protein FAM5C precursor (DBCCR1-like protein 1). -
           Takifugu rubripes
          Length = 774

 Score = 31.9 bits (69), Expect = 8.9
 Identities = 18/59 (30%), Positives = 32/59 (54%)
 Frame = +2

Query: 140 YRRFSGSEQDSRMPHVRPCSDQTMVLFRSSIQHLQFYWSDSNQVNSY*ERSYRRSCQAE 316
           ++ FS S++ SR P +    +++   + S  Q L  Y S++NQ+  + E  +  SCQ E
Sbjct: 383 FKLFSLSKRCSRQPQIHLPRERSQSYWLSHFQSL-LYCSENNQLGDFSEELHSCSCQYE 440


>UniRef50_Q6MQ30 Cluster: Tetracycline-efflux transporter; n=1;
           Bdellovibrio bacteriovorus|Rep: Tetracycline-efflux
           transporter - Bdellovibrio bacteriovorus
          Length = 367

 Score = 31.9 bits (69), Expect = 8.9
 Identities = 37/162 (22%), Positives = 65/162 (40%), Gaps = 4/162 (2%)
 Frame = +3

Query: 18  KFGFTEVEYSIYGTINIVVGLLGTI----FCILVLSKRMNVQDSIIGALAGVSRIAGCLM 185
           ++G+T  +    G    VVGLL  +       LV+ K    +  +IGA          + 
Sbjct: 211 RYGWTTAQV---GLSLAVVGLLSALAQGWLTRLVIPKFGEHRTVVIGAFGYA---VSFIF 264

Query: 186 FALAPTRQWFYSAPLFNIFSFTGLTAIRSIATKSVPTEEVAKLSALMGVTESLAPSIYMP 365
           + +A      Y+  + +   +T   A++S+ +   P +E  +L   +    SLA  I   
Sbjct: 265 YGMATEGWMMYAILILSAVFWTSPPALQSLISHKTPPQEQGELQGSLVSLSSLAAIITPL 324

Query: 366 ASSYIYMSTIETFPGAFYLFDAALTVVALCLFGMIYILARKK 491
            ++ ++       PG  YL  A     AL  F    I+ R+K
Sbjct: 325 VTTKLFAHFSSGNPGTLYLPGAPYYFGALICFVSWAIMYRRK 366


>UniRef50_Q048R1 Cluster: Permease of the major facilitator
           superfamily; n=2; Lactobacillus delbrueckii subsp.
           bulgaricus|Rep: Permease of the major facilitator
           superfamily - Lactobacillus delbrueckii subsp.
           bulgaricus (strain ATCC BAA-365)
          Length = 400

 Score = 31.9 bits (69), Expect = 8.9
 Identities = 31/158 (19%), Positives = 65/158 (41%), Gaps = 1/158 (0%)
 Frame = +3

Query: 21  FGFTEVEYSIYGTINIVVGLLGTIFCILVLSKRMNVQDSIIGALAGVSRIAGCLMFALAP 200
           F F++  Y+ + T   V GLLG +   L+  +  +     I A+AG+      +M +L  
Sbjct: 245 FAFSKNAYAFFLTAESVGGLLGAVASNLIQKELSSKYLFWIIAVAGLPL---AVMSSLYQ 301

Query: 201 TRQWFYSAPL-FNIFSFTGLTAIRSIATKSVPTEEVAKLSALMGVTESLAPSIYMPASSY 377
              W + + +   +F+F          T      ++  +  +  +  + A  I++P  S+
Sbjct: 302 VSHWLFGSIICITLFNFCVSVFNIQFMTYIQTNADMTYIGRVFSIVFT-AAIIFVPLGSF 360

Query: 378 IYMSTIETFPGAFYLFDAALTVVALCLFGMIYILARKK 491
            +   ++      YL+   L      L  +IY L +++
Sbjct: 361 FFQFVMDVKDSVDYLWLGGLLTFVAGLASVIYSLNQRR 398


>UniRef50_Q03N16 Cluster: Beta-lactamase class A; n=3; Streptococcus
           thermophilus|Rep: Beta-lactamase class A - Streptococcus
           thermophilus (strain ATCC BAA-491 / LMD-9)
          Length = 430

 Score = 31.9 bits (69), Expect = 8.9
 Identities = 16/45 (35%), Positives = 23/45 (51%)
 Frame = +3

Query: 282 KSVPTEEVAKLSALMGVTESLAPSIYMPASSYIYMSTIETFPGAF 416
           KS+    +AKL  L    E L+      ++ Y Y ST+  FPGA+
Sbjct: 227 KSMYAASIAKLGVLYYAQERLSQKKLSLSNEYQYTSTVNGFPGAY 271


>UniRef50_A7I0C7 Cluster: Putative quinolone resistence protein,
           major facilitator family transporter; n=1; Campylobacter
           hominis ATCC BAA-381|Rep: Putative quinolone resistence
           protein, major facilitator family transporter -
           Campylobacter hominis (strain ATCC BAA-381 / LMG 19568 /
           NCTC 13146 /CH001A)
          Length = 370

 Score = 31.9 bits (69), Expect = 8.9
 Identities = 22/74 (29%), Positives = 32/74 (43%)
 Frame = +3

Query: 240 FSFTGLTAIRSIATKSVPTEEVAKLSALMGVTESLAPSIYMPASSYIYMSTIETFPGAFY 419
           FSFT L  +  +  KS  T +   +  ++  T +LA     P S  + +     F G FY
Sbjct: 19  FSFTSLLQVLPLYLKSFDTSDF--MIGIINATFTLAAIFARPFSGKL-LGIFSRF-GTFY 74

Query: 420 LFDAALTVVALCLF 461
            F A   +  LC F
Sbjct: 75  FFTAIFFIATLCYF 88


>UniRef50_A0R2Y6 Cluster: Conserved membrane-spanning protein; n=14;
           Mycobacterium|Rep: Conserved membrane-spanning protein -
           Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155)
          Length = 576

 Score = 31.9 bits (69), Expect = 8.9
 Identities = 17/31 (54%), Positives = 20/31 (64%)
 Frame = -2

Query: 254 TSKTEDVE*RSGIEPLSGRSKGEHEASCYPA 162
           T  TEDV+ RSG EP + R+ G HEA   PA
Sbjct: 4   TKTTEDVD-RSGGEPHAARAAGHHEAPDKPA 33


  Database: uniref50
    Posted date:  Oct 5, 2007 11:19 AM
  Number of letters in database: 575,637,011
  Number of sequences in database:  1,657,284
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 507,468,188
Number of Sequences: 1657284
Number of extensions: 9620840
Number of successful extensions: 24876
Number of sequences better than 10.0: 67
Number of HSP's better than 10.0 without gapping: 24290
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 24858
length of database: 575,637,011
effective HSP length: 95
effective length of database: 418,195,031
effective search space used: 31782822356
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

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