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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= brS-0065
         (722 letters)

Database: uniref50 
           1,657,284 sequences; 575,637,011 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

UniRef50_UPI0000E481DE Cluster: PREDICTED: hypothetical protein;...   322   4e-87
UniRef50_Q9VD23 Cluster: Pyruvate kinase; n=5; Coelomata|Rep: Py...   313   3e-84
UniRef50_UPI0000D5551D Cluster: PREDICTED: similar to Pyruvate k...   308   9e-83
UniRef50_P30613 Cluster: Pyruvate kinase isozymes R/L; n=167; Fu...   304   1e-81
UniRef50_Q27686 Cluster: Pyruvate kinase; n=16; Kinetoplastida|R...   276   4e-73
UniRef50_Q7RVA8 Cluster: Pyruvate kinase; n=11; Ascomycota|Rep: ...   276   5e-73
UniRef50_O44006 Cluster: Pyruvate kinase; n=10; cellular organis...   270   3e-71
UniRef50_Q42806 Cluster: Pyruvate kinase, cytosolic isozyme; n=6...   262   8e-69
UniRef50_Q9KUN0 Cluster: Pyruvate kinase; n=24; cellular organis...   254   2e-66
UniRef50_P52489 Cluster: Pyruvate kinase 2; n=33; Dikarya|Rep: P...   254   2e-66
UniRef50_Q9M057 Cluster: Pyruvate kinase; n=11; Magnoliophyta|Re...   254   2e-66
UniRef50_Q9VFG4 Cluster: Pyruvate kinase; n=3; Sophophora|Rep: P...   246   6e-64
UniRef50_P77983 Cluster: Pyruvate kinase I; n=29; Bacteria|Rep: ...   244   1e-63
UniRef50_Q22Z06 Cluster: Pyruvate kinase family protein; n=3; Ol...   240   3e-62
UniRef50_P80885 Cluster: Pyruvate kinase; n=161; Bacteria|Rep: P...   236   3e-61
UniRef50_Q4U977 Cluster: Pyruvate kinase, putative; n=3; Piropla...   234   2e-60
UniRef50_Q9VQH0 Cluster: Pyruvate kinase; n=3; Sophophora|Rep: P...   229   4e-59
UniRef50_Q2TSW8 Cluster: Pyruvate kinase; n=4; stramenopiles|Rep...   228   9e-59
UniRef50_Q2TSW6 Cluster: Pyruvate kinase; n=1; Achlya bisexualis...   227   2e-58
UniRef50_P73534 Cluster: Pyruvate kinase 2; n=37; Bacteria|Rep: ...   219   4e-56
UniRef50_UPI00006CE5D4 Cluster: pyruvate kinase family protein; ...   217   2e-55
UniRef50_A4E9R2 Cluster: Pyruvate kinase; n=1; Collinsella aerof...   217   2e-55
UniRef50_Q55863 Cluster: Pyruvate kinase 1; n=5; Cyanobacteria|R...   214   2e-54
UniRef50_Q6AII5 Cluster: Pyruvate kinase; n=1; Desulfotalea psyc...   213   5e-54
UniRef50_Q64MR8 Cluster: Pyruvate kinase; n=6; Bacteroides|Rep: ...   212   9e-54
UniRef50_Q1FK29 Cluster: Pyruvate kinase; n=4; Clostridiales|Rep...   211   1e-53
UniRef50_A6DH47 Cluster: Pyruvate kinase; n=1; Lentisphaera aran...   210   3e-53
UniRef50_Q6MAN9 Cluster: Pyruvate kinase; n=1; Candidatus Protoc...   210   3e-53
UniRef50_Q747D6 Cluster: Pyruvate kinase; n=6; Desulfuromonadale...   208   8e-53
UniRef50_A6LH43 Cluster: Pyruvate kinase; n=2; Parabacteroides|R...   208   1e-52
UniRef50_Q8F253 Cluster: Pyruvate kinase; n=4; Leptospira|Rep: P...   207   2e-52
UniRef50_Q5V4I8 Cluster: Pyruvate kinase; n=4; Halobacteriaceae|...   206   3e-52
UniRef50_Q2JLA2 Cluster: Pyruvate kinase; n=2; Synechococcus|Rep...   205   7e-52
UniRef50_Q2IHE2 Cluster: Pyruvate kinase; n=1; Anaeromyxobacter ...   205   1e-51
UniRef50_Q1Q4I4 Cluster: Strongly similar to pyruvate kinase; n=...   205   1e-51
UniRef50_Q1IHI1 Cluster: Pyruvate kinase; n=2; Bacteria|Rep: Pyr...   205   1e-51
UniRef50_A3I0G9 Cluster: Pyruvate kinase; n=3; Flexibacteraceae|...   204   2e-51
UniRef50_Q8SQP0 Cluster: Pyruvate kinase; n=1; Encephalitozoon c...   203   4e-51
UniRef50_Q6A9P1 Cluster: Pyruvate kinase; n=4; Actinomycetales|R...   202   7e-51
UniRef50_Q4SVB7 Cluster: Pyruvate kinase; n=1; Tetraodon nigrovi...   202   9e-51
UniRef50_Q6YQT6 Cluster: Pyruvate kinase; n=6; Candidatus Phytop...   202   9e-51
UniRef50_Q0W8N0 Cluster: Pyruvate kinase; n=7; cellular organism...   201   1e-50
UniRef50_A6FYT4 Cluster: Pyruvate kinase; n=1; Plesiocystis paci...   201   2e-50
UniRef50_Q07637 Cluster: Pyruvate kinase; n=44; Streptococcaceae...   200   3e-50
UniRef50_A6Q5W9 Cluster: Pyruvate kinase; n=2; Epsilonproteobact...   198   9e-50
UniRef50_Q8EX62 Cluster: Pyruvate kinase; n=5; Bacteria|Rep: Pyr...   198   1e-49
UniRef50_A6PUS2 Cluster: Pyruvate kinase; n=1; Victivallis vaden...   198   1e-49
UniRef50_Q7UF82 Cluster: Pyruvate kinase; n=1; Pirellula sp.|Rep...   197   2e-49
UniRef50_Q1AXJ8 Cluster: Pyruvate kinase; n=1; Rubrobacter xylan...   197   3e-49
UniRef50_Q2S3S2 Cluster: Pyruvate kinase; n=1; Salinibacter rube...   196   5e-49
UniRef50_A7CUA8 Cluster: Pyruvate kinase; n=1; Opitutaceae bacte...   196   5e-49
UniRef50_Q8YTZ8 Cluster: Pyruvate kinase; n=3; Nostocaceae|Rep: ...   196   6e-49
UniRef50_A7HIL5 Cluster: Pyruvate kinase; n=9; Bacteria|Rep: Pyr...   196   6e-49
UniRef50_Q6F1U1 Cluster: Pyruvate kinase; n=10; Mollicutes|Rep: ...   194   1e-48
UniRef50_Q08SK3 Cluster: Pyruvate kinase; n=2; Cystobacterineae|...   194   2e-48
UniRef50_Q9RR62 Cluster: Pyruvate kinase; n=5; Bacteria|Rep: Pyr...   192   6e-48
UniRef50_O51323 Cluster: Pyruvate kinase; n=5; cellular organism...   192   6e-48
UniRef50_Q1MPC8 Cluster: Pyruvate kinase; n=4; Desulfovibrionace...   192   7e-48
UniRef50_Q3JCE7 Cluster: Pyruvate kinase; n=1; Nitrosococcus oce...   191   1e-47
UniRef50_Q6MLB5 Cluster: Pyruvate kinase; n=1; Bdellovibrio bact...   191   2e-47
UniRef50_Q1K4D5 Cluster: Pyruvate kinase; n=1; Desulfuromonas ac...   191   2e-47
UniRef50_Q6KHW9 Cluster: Pyruvate kinase; n=3; Mycoplasma|Rep: P...   190   2e-47
UniRef50_A4MK73 Cluster: Pyruvate kinase; n=1; Petrotoga mobilis...   190   2e-47
UniRef50_A7D456 Cluster: Pyruvate kinase; n=2; Halobacteriaceae|...   190   4e-47
UniRef50_Q8PYY4 Cluster: Pyruvate kinase; n=3; Methanosarcinacea...   189   5e-47
UniRef50_Q44473 Cluster: Pyruvate kinase; n=4; Proteobacteria|Re...   189   7e-47
UniRef50_Q1NTW3 Cluster: Pyruvate kinase; n=1; delta proteobacte...   188   9e-47
UniRef50_Q2I6K6 Cluster: Pyruvate kinase; n=1; uncultured delta ...   188   2e-46
UniRef50_A6Q7D7 Cluster: Pyruvate kinase; n=19; cellular organis...   188   2e-46
UniRef50_Q46078 Cluster: Pyruvate kinase; n=19; Actinobacteria (...   186   4e-46
UniRef50_O06134 Cluster: Pyruvate kinase; n=29; Bacteria|Rep: Py...   186   5e-46
UniRef50_Q1IJ65 Cluster: Pyruvate kinase; n=6; Bacteria|Rep: Pyr...   185   1e-45
UniRef50_A4APL1 Cluster: Pyruvate kinase; n=15; Bacteroidetes|Re...   184   1e-45
UniRef50_P94685 Cluster: Pyruvate kinase; n=8; Chlamydiaceae|Rep...   184   2e-45
UniRef50_A1BQT0 Cluster: Pyruvate kinase; n=2; Eukaryota|Rep: Py...   184   3e-45
UniRef50_Q8G5M1 Cluster: Pyruvate kinase; n=23; Actinobacteridae...   183   3e-45
UniRef50_A0QNT2 Cluster: Pyruvate kinase; n=1; Mycobacterium sme...   183   5e-45
UniRef50_Q81N35 Cluster: Pyruvate kinase; n=11; Bacillus cereus ...   182   6e-45
UniRef50_A0L7K0 Cluster: Pyruvate kinase; n=1; Magnetococcus sp....   181   1e-44
UniRef50_O05118 Cluster: Pyruvate kinase; n=44; Proteobacteria|R...   181   2e-44
UniRef50_Q57572 Cluster: Pyruvate kinase; n=6; Methanococcales|R...   179   7e-44
UniRef50_Q7P1G4 Cluster: Pyruvate kinase; n=4; Bacteria|Rep: Pyr...   178   1e-43
UniRef50_A1IEN3 Cluster: Pyruvate kinase; n=1; Candidatus Desulf...   177   2e-43
UniRef50_A7CAK5 Cluster: Pyruvate kinase; n=3; Ralstonia pickett...   177   3e-43
UniRef50_Q56XD5 Cluster: Pyruvate kinase; n=14; Magnoliophyta|Re...   176   4e-43
UniRef50_Q40546 Cluster: Pyruvate kinase isozyme G, chloroplast ...   176   4e-43
UniRef50_UPI00015BD1E0 Cluster: UPI00015BD1E0 related cluster; n...   176   5e-43
UniRef50_Q63P20 Cluster: Pyruvate kinase; n=74; Proteobacteria|R...   176   5e-43
UniRef50_Q9PF54 Cluster: Pyruvate kinase; n=11; Xanthomonadaceae...   175   7e-43
UniRef50_Q8TJ98 Cluster: Pyruvate kinase; n=2; Methanomicrobia|R...   175   7e-43
UniRef50_A0L5K6 Cluster: Pyruvate kinase; n=5; Proteobacteria|Re...   175   9e-43
UniRef50_A3ZTM3 Cluster: Pyruvate kinase; n=1; Blastopirellula m...   175   1e-42
UniRef50_Q8EWX2 Cluster: Pyruvate kinase; n=1; Mycoplasma penetr...   173   3e-42
UniRef50_Q94KE3 Cluster: Pyruvate kinase; n=25; Magnoliophyta|Re...   173   5e-42
UniRef50_A5C814 Cluster: Pyruvate kinase; n=1; Vitis vinifera|Re...   171   2e-41
UniRef50_Q9WY51 Cluster: Pyruvate kinase; n=3; Thermotogaceae|Re...   169   6e-41
UniRef50_A6C474 Cluster: Pyruvate kinase; n=1; Planctomyces mari...   168   1e-40
UniRef50_A5JEK8 Cluster: Pyruvate kinase; n=1; Nosema bombycis|R...   168   1e-40
UniRef50_P32044 Cluster: Pyruvate kinase; n=2; Thermoplasma|Rep:...   168   1e-40
UniRef50_Q1ZJ78 Cluster: Pyruvate kinase; n=1; Psychromonas sp. ...   165   1e-39
UniRef50_Q8ZNW0 Cluster: Pyruvate kinase II; n=173; Proteobacter...   164   2e-39
UniRef50_Q82XE9 Cluster: Pyruvate kinase family; n=130; Proteoba...   164   2e-39
UniRef50_Q2TSX0 Cluster: Pyruvate kinase; n=2; cellular organism...   163   4e-39
UniRef50_Q5ZZ75 Cluster: Pyruvate kinase II; n=4; Legionella pne...   161   1e-38
UniRef50_Q0C0E8 Cluster: Pyruvate kinase; n=1; Hyphomonas neptun...   161   1e-38
UniRef50_A1RX09 Cluster: Pyruvate kinase; n=1; Thermofilum pende...   161   2e-38
UniRef50_P78031 Cluster: Pyruvate kinase; n=6; Mycoplasma|Rep: P...   159   6e-38
UniRef50_Q6L281 Cluster: Pyruvate kinase; n=2; Thermoplasmatales...   157   3e-37
UniRef50_A7QH42 Cluster: Chromosome chr3 scaffold_95, whole geno...   156   6e-37
UniRef50_Q97ZD7 Cluster: Pyruvate kinase; n=4; Sulfolobaceae|Rep...   154   2e-36
UniRef50_Q2FMN4 Cluster: Pyruvate kinase; n=1; Methanospirillum ...   154   2e-36
UniRef50_Q0AHE3 Cluster: Pyruvate kinase; n=2; Nitrosomonadaceae...   154   2e-36
UniRef50_A3ALA5 Cluster: Pyruvate kinase; n=3; Oryza sativa|Rep:...   153   4e-36
UniRef50_A1WED1 Cluster: Pyruvate kinase; n=1; Verminephrobacter...   150   3e-35
UniRef50_Q40545 Cluster: Pyruvate kinase isozyme A, chloroplast ...   149   9e-35
UniRef50_Q648E3 Cluster: Pyruvate kinase; n=1; uncultured archae...   146   5e-34
UniRef50_A2BLH1 Cluster: Pyruvate kinase; n=1; Hyperthermus buty...   144   2e-33
UniRef50_Q9YEU2 Cluster: Pyruvate kinase; n=1; Aeropyrum pernix|...   143   3e-33
UniRef50_Q9PQV7 Cluster: Pyruvate kinase; n=1; Ureaplasma parvum...   140   2e-32
UniRef50_A3DMY9 Cluster: Pyruvate kinase; n=1; Staphylothermus m...   137   3e-31
UniRef50_Q22CT0 Cluster: Pyruvate kinase, barrel domain containi...   132   6e-30
UniRef50_Q8IJ37 Cluster: Pyruvate kinase; n=7; Plasmodium|Rep: P...   128   1e-28
UniRef50_Q22AI0 Cluster: Pyruvate kinase, barrel domain containi...   126   4e-28
UniRef50_UPI0000DB6F59 Cluster: PREDICTED: similar to Pyruvate k...   121   2e-26
UniRef50_Q7QVW2 Cluster: Pyruvate kinase; n=1; Giardia lamblia A...   118   1e-25
UniRef50_A3H760 Cluster: Pyruvate kinase; n=1; Caldivirga maquil...   118   1e-25
UniRef50_Q4N603 Cluster: Pyruvate kinase; n=2; Theileria|Rep: Py...   116   8e-25
UniRef50_A7PC98 Cluster: Chromosome chr2 scaffold_11, whole geno...   115   1e-24
UniRef50_A7APT5 Cluster: Pyruvate kinase family protein; n=1; Ba...   115   1e-24
UniRef50_Q8TGR8 Cluster: Uncharacterized protein YAL037C-B; n=1;...   115   1e-24
UniRef50_Q9V2V8 Cluster: Pyruvate kinase; n=1; Thermoproteus ten...   111   1e-23
UniRef50_Q8ZYE0 Cluster: Pyruvate kinase; n=4; Pyrobaculum|Rep: ...   109   5e-23
UniRef50_Q090R5 Cluster: Pyruvate kinase; n=1; Stigmatella auran...   108   1e-22
UniRef50_A0BDA7 Cluster: Pyruvate kinase; n=3; Alveolata|Rep: Py...   107   3e-22
UniRef50_Q5M6U9 Cluster: Pyruvate kinase; n=2; Campylobacter jej...   107   4e-22
UniRef50_UPI000155B976 Cluster: PREDICTED: similar to pyruvate k...   106   6e-22
UniRef50_UPI0000D56D72 Cluster: PREDICTED: similar to CG7070-PB,...   104   2e-21
UniRef50_Q9M3B6 Cluster: Pyruvate kinase; n=1; Arabidopsis thali...   103   3e-21
UniRef50_Q7NJ33 Cluster: Pyruvate kinase; n=1; Gloeobacter viola...   103   6e-21
UniRef50_Q8XLL6 Cluster: Pyruvate kinase; n=3; Clostridium perfr...   101   2e-20
UniRef50_A7QTW5 Cluster: Chromosome undetermined scaffold_171, w...    99   1e-19
UniRef50_A0BIN1 Cluster: Pyruvate kinase; n=2; Paramecium tetrau...    97   5e-19
UniRef50_A3PTF7 Cluster: Pyruvate kinase; n=5; Mycobacterium|Rep...    95   2e-18
UniRef50_Q062W1 Cluster: Pyruvate kinase; n=1; Synechococcus sp....    95   2e-18
UniRef50_A1U5Q4 Cluster: Pyruvate kinase; n=2; Marinobacter aqua...    93   5e-18
UniRef50_O58306 Cluster: Putative uncharacterized protein PH0571...    93   6e-18
UniRef50_Q5KVI2 Cluster: Pyruvate kinase; n=2; Geobacillus|Rep: ...    92   1e-17
UniRef50_A0NLM6 Cluster: Pyruvate kinase; n=2; Alphaproteobacter...    92   1e-17
UniRef50_A4VPY3 Cluster: Pyruvate kinase; n=1; Pseudomonas stutz...    91   2e-17
UniRef50_A4ARB8 Cluster: Pyruvate kinase; n=1; Flavobacteriales ...    91   3e-17
UniRef50_A6LTB0 Cluster: Pyruvate kinase; n=1; Clostridium beije...    90   6e-17
UniRef50_Q3J5D7 Cluster: Pyruvate kinase; n=2; Rhodobacter sphae...    87   4e-16
UniRef50_Q8FLV7 Cluster: Pyruvate kinase; n=6; Corynebacterium|R...    87   5e-16
UniRef50_Q8DLH6 Cluster: Pyruvate kinase; n=2; Synechococcus|Rep...    86   1e-15
UniRef50_Q19Q27 Cluster: Acyl-CoA desaturase-like; n=2; Belgica ...    81   3e-14
UniRef50_Q9U016 Cluster: Pyruvate kinase; n=2; Giardia intestina...    81   4e-14
UniRef50_Q2JJ60 Cluster: Pyruvate kinase; n=5; Bacteria|Rep: Pyr...    80   6e-14
UniRef50_UPI000049906E Cluster: pyruvate kinase; n=3; Entamoeba ...    65   2e-09
UniRef50_A7CFG4 Cluster: Putative uncharacterized protein; n=1; ...    58   2e-07
UniRef50_Q59ZE3 Cluster: Putative uncharacterized protein; n=1; ...    55   2e-06
UniRef50_Q3JI08 Cluster: Putative uncharacterized protein; n=3; ...    45   0.002
UniRef50_Q676G7 Cluster: Pyruvate kinase; n=1; Agrobacterium tum...    45   0.002
UniRef50_A5P062 Cluster: Putative uncharacterized protein; n=2; ...    45   0.002
UniRef50_Q56301 Cluster: Pyruvate kinase; n=5; Thermococcaceae|R...    44   0.004
UniRef50_Q0PQH4 Cluster: Pyruvate kinase; n=1; Endoriftia persep...    43   0.007
UniRef50_A5BYI4 Cluster: Pyruvate kinase; n=1; Vitis vinifera|Re...    43   0.009
UniRef50_Q4JN61 Cluster: CG7362-PA; n=1; uncultured bacterium BA...    39   0.11 
UniRef50_Q8CA87 Cluster: Adult male spinal cord cDNA, RIKEN full...    38   0.33 
UniRef50_A0IJJ4 Cluster: HpcH/HpaI aldolase; n=2; Bacteria|Rep: ...    36   0.77 
UniRef50_Q54CD8 Cluster: Putative RNA helicase; n=2; Dictyosteli...    36   1.3  
UniRef50_A6RIB2 Cluster: Putative uncharacterized protein; n=1; ...    34   3.1  
UniRef50_A3LQY4 Cluster: Predicted protein; n=1; Pichia stipitis...    34   3.1  
UniRef50_Q0EZ03 Cluster: Putative uncharacterized protein; n=2; ...    34   4.1  
UniRef50_A7TH49 Cluster: Putative uncharacterized protein; n=1; ...    34   4.1  
UniRef50_Q9LSA0 Cluster: Emb|CAB62463.1; n=3; Arabidopsis thalia...    33   5.4  
UniRef50_Q6IKV8 Cluster: HDC11342; n=2; Drosophila melanogaster|...    33   5.4  
UniRef50_P23522 Cluster: 2-dehydro-3-deoxyglucarate aldolase; n=...    33   5.4  
UniRef50_Q6VZK4 Cluster: CNPV143 ankyrin repeat protein; n=1; Ca...    33   7.1  
UniRef50_Q893T5 Cluster: Flagellar hook-associated protein 1; n=...    33   7.1  
UniRef50_Q5YWM7 Cluster: Putative uncharacterized protein; n=1; ...    33   7.1  
UniRef50_Q1NHC0 Cluster: Putative uncharacterized protein; n=1; ...    33   7.1  
UniRef50_Q0YHY4 Cluster: Protein-glutamate O-methyltransferase; ...    33   7.1  
UniRef50_Q04GL6 Cluster: RecG-like helicase; n=5; Lactobacillale...    33   7.1  
UniRef50_A0Y985 Cluster: Zinc-containing alcohol dehydrogenase s...    33   7.1  
UniRef50_Q949D7 Cluster: Putative uncharacterized protein C555ER...    33   7.1  
UniRef50_Q8F846 Cluster: Putative uncharacterized protein; n=2; ...    33   9.4  
UniRef50_A3XHP8 Cluster: Putative uncharacterized protein; n=1; ...    33   9.4  

>UniRef50_UPI0000E481DE Cluster: PREDICTED: hypothetical protein;
           n=1; Strongylocentrotus purpuratus|Rep: PREDICTED:
           hypothetical protein - Strongylocentrotus purpuratus
          Length = 461

 Score =  322 bits (792), Expect = 4e-87
 Identities = 155/233 (66%), Positives = 178/233 (76%)
 Frame = +1

Query: 22  NAGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGIL 201
           N GMLGSRKGVNLP   VDLPA+SEKDK DL FG+E GV+M+FASFIR    +H++R +L
Sbjct: 127 NGGMLGSRKGVNLPNAEVDLPALSEKDKGDLRFGLEHGVEMVFASFIRKATDVHQVREVL 186

Query: 202 GEKGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCN 381
           GE+G +IKIISKIEN +G+   DEI+  SDGIMVARGDLGIEIPPEKVFLAQK MI+RCN
Sbjct: 187 GEQGAHIKIISKIENQEGVAKFDEILEASDGIMVARGDLGIEIPPEKVFLAQKMMISRCN 246

Query: 382 RVGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTM 561
           ++GK VICATQMLESMV  PRPTRAE SDVANA+LDGADCVMLSGETAKG YPVE V  M
Sbjct: 247 KIGKSVICATQMLESMVNNPRPTRAETSDVANAVLDGADCVMLSGETAKGKYPVEAVSMM 306

Query: 562 ANICKEAEAVIWHRQLFNDLVSEVKPPIDPXXXXXXXXXXXXTKCLASAIVVI 720
             I +EAEA ++HRQ F +L  EV  P                KCLA AI+V+
Sbjct: 307 HRISREAEAAVFHRQQFEELTREVDMPTSAGLTVAIAAVEASYKCLAGAIIVL 359


>UniRef50_Q9VD23 Cluster: Pyruvate kinase; n=5; Coelomata|Rep:
           Pyruvate kinase - Drosophila melanogaster (Fruit fly)
          Length = 744

 Score =  313 bits (769), Expect = 3e-84
 Identities = 148/208 (71%), Positives = 170/208 (81%)
 Frame = +1

Query: 13  QQDNAGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIR 192
           Q +N G LGS KG+NLPG+PVDLP+V+EKDK DL FG EQ VDMIFASFIR+  AL EIR
Sbjct: 129 QVENGGKLGSHKGINLPGVPVDLPSVTEKDKQDLKFGAEQKVDMIFASFIRDANALKEIR 188

Query: 193 GILGEKGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIA 372
            +LG  G  IKIISKIENHQG+VN+D+II ESDGIMVARGD+GIEIP E V LAQK+++A
Sbjct: 189 QVLGPAGACIKIISKIENHQGLVNIDDIIRESDGIMVARGDMGIEIPTEDVPLAQKSIVA 248

Query: 373 RCNRVGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECV 552
           +CN+VGKPVICATQM+ESM  KPRPTRAE SDVANAI DG D VMLSGETAKG YPVECV
Sbjct: 249 KCNKVGKPVICATQMMESMTNKPRPTRAEASDVANAIFDGCDAVMLSGETAKGKYPVECV 308

Query: 553 HTMANICKEAEAVIWHRQLFNDLVSEVK 636
             MA IC + EAV+W+  L N L  E++
Sbjct: 309 QCMARICAKVEAVLWYESLQNSLKREIR 336


>UniRef50_UPI0000D5551D Cluster: PREDICTED: similar to Pyruvate
           kinase (PK); n=1; Tribolium castaneum|Rep: PREDICTED:
           similar to Pyruvate kinase (PK) - Tribolium castaneum
          Length = 557

 Score =  308 bits (756), Expect = 9e-83
 Identities = 138/233 (59%), Positives = 174/233 (74%)
 Frame = +1

Query: 19  DNAGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGI 198
           +N GMLGS K VNLPGI +DLP VSEKDK DLLFGVE G+D + ASFIRN   + E+R +
Sbjct: 205 ENGGMLGSCKNVNLPGIDIDLPVVSEKDKEDLLFGVEHGIDTVHASFIRNAVDVSEVRDV 264

Query: 199 LGEKGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARC 378
           LG  G  I IISKIENHQG+ N+DEII  SDGIM+ RGDL +EI PEK+FLAQK++IA+C
Sbjct: 265 LGRAGNKILIISKIENHQGVHNIDEIIKASDGIMIGRGDLAVEIGPEKLFLAQKSIIAKC 324

Query: 379 NRVGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHT 558
           N+ GKPVICA Q+L SM+K+PRPTRAE +DVANA+LDG DCVML+GET  G +P+EC+  
Sbjct: 325 NKAGKPVICANQLLYSMIKRPRPTRAECTDVANAVLDGVDCVMLTGETFLGQHPIECIRA 384

Query: 559 MANICKEAEAVIWHRQLFNDLVSEVKPPIDPXXXXXXXXXXXXTKCLASAIVV 717
            + ICKEAE  IW++  F +L+   +PP++              +CLA+AI+V
Sbjct: 385 ASKICKEAEGAIWYKHHFRELIGHARPPLETSHTICIAAVEAANQCLAAAIIV 437


>UniRef50_P30613 Cluster: Pyruvate kinase isozymes R/L; n=167;
           Fungi/Metazoa group|Rep: Pyruvate kinase isozymes R/L -
           Homo sapiens (Human)
          Length = 574

 Score =  304 bits (747), Expect = 1e-81
 Identities = 147/236 (62%), Positives = 174/236 (73%)
 Frame = +1

Query: 13  QQDNAGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIR 192
           Q +N G+LGSRKGVNLPG  VDLP +SE+D  DL FGVE GVD++FASF+R  + +  +R
Sbjct: 239 QVENGGVLGSRKGVNLPGAQVDLPGLSEQDVRDLRFGVEHGVDIVFASFVRKASDVAAVR 298

Query: 193 GILGEKGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIA 372
             LG +G  IKIISKIENH+G+   DEI+  SDGIMVARGDLGIEIP EKVFLAQK MI 
Sbjct: 299 AALGPEGHGIKIISKIENHEGVKRFDEILEVSDGIMVARGDLGIEIPAEKVFLAQKMMIG 358

Query: 373 RCNRVGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECV 552
           RCN  GKPV+CATQMLESM+ KPRPTRAE SDVANA+LDGADC+MLSGETAKG++PVE V
Sbjct: 359 RCNLAGKPVVCATQMLESMITKPRPTRAETSDVANAVLDGADCIMLSGETAKGNFPVEAV 418

Query: 553 HTMANICKEAEAVIWHRQLFNDLVSEVKPPIDPXXXXXXXXXXXXTKCLASAIVVI 720
                I +EAEA ++HRQLF +L        DP             KC A+AI+V+
Sbjct: 419 KMQHAIAREAEAAVYHRQLFEELRRAAPLSRDPTEVTAIGAVEAAFKCCAAAIIVL 474


>UniRef50_Q27686 Cluster: Pyruvate kinase; n=16; Kinetoplastida|Rep:
           Pyruvate kinase - Leishmania mexicana
          Length = 499

 Score =  276 bits (677), Expect = 4e-73
 Identities = 137/233 (58%), Positives = 166/233 (71%)
 Frame = +1

Query: 22  NAGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGIL 201
           N+  +  R+GVNLPG  VDLPAVS KD+ DL FGVEQGVDMIFASFIR+   + ++R  L
Sbjct: 168 NSHTISDRRGVNLPGCDVDLPAVSAKDRVDLQFGVEQGVDMIFASFIRSAEQVGDVRKAL 227

Query: 202 GEKGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCN 381
           G KG++I II KIENHQG+ N+D II ESDGIMVARGDLG+EIP EKV +AQK +I++CN
Sbjct: 228 GPKGRDIMIICKIENHQGVQNIDSIIEESDGIMVARGDLGVEIPAEKVVVAQKILISKCN 287

Query: 382 RVGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTM 561
             GKPVICATQMLESM   PRPTRAE+SDVANA+ +GADCVMLSGETAKG YP E V  M
Sbjct: 288 VAGKPVICATQMLESMTYNPRPTRAEVSDVANAVFNGADCVMLSGETAKGKYPNEVVQYM 347

Query: 562 ANICKEAEAVIWHRQLFNDLVSEVKPPIDPXXXXXXXXXXXXTKCLASAIVVI 720
           A IC EA++ +     FN +      P+              ++  A A+VV+
Sbjct: 348 ARICLEAQSALNEYVFFNSIKKLQHIPMSADEAVCGSAVNSVSETKAKAMVVL 400


>UniRef50_Q7RVA8 Cluster: Pyruvate kinase; n=11; Ascomycota|Rep:
           Pyruvate kinase - Neurospora crassa
          Length = 527

 Score =  276 bits (676), Expect = 5e-73
 Identities = 135/208 (64%), Positives = 158/208 (75%)
 Frame = +1

Query: 22  NAGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGIL 201
           N G + SRKGVNLP   VDLPA+SEKDK+DL FGV+  VDM+FASFIR G  + +IR +L
Sbjct: 182 NNGYISSRKGVNLPNTDVDLPALSEKDKADLRFGVKNKVDMVFASFIRRGQDIKDIREVL 241

Query: 202 GEKGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCN 381
           GE GK I+II+KIEN QG+ N  EI+AE+DG+MVARGDLGIEIP  +VF AQK +IA CN
Sbjct: 242 GEDGKQIQIIAKIENRQGLNNFAEILAETDGVMVARGDLGIEIPAAEVFAAQKKIIAMCN 301

Query: 382 RVGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTM 561
             GKPVICATQMLESM+K PRPTRAEISDV NA+ DGADCVMLSGETAKG YP E V  M
Sbjct: 302 IAGKPVICATQMLESMIKNPRPTRAEISDVGNAVTDGADCVMLSGETAKGAYPTEAVREM 361

Query: 562 ANICKEAEAVIWHRQLFNDLVSEVKPPI 645
           +    +AE  I +   F +L S  K P+
Sbjct: 362 SEAVLKAENTIPYVSHFEELCSLAKRPV 389


>UniRef50_O44006 Cluster: Pyruvate kinase; n=10; cellular
           organisms|Rep: Pyruvate kinase - Eimeria tenella
          Length = 531

 Score =  270 bits (661), Expect = 3e-71
 Identities = 126/210 (60%), Positives = 160/210 (76%), Gaps = 1/210 (0%)
 Frame = +1

Query: 22  NAGMLGSRKGVNLPGIPVDLPAVSEKDKSDLL-FGVEQGVDMIFASFIRNGAALHEIRGI 198
           N  ++G++K +NLPG+ VDLP + EKDK+D+L FG+  G + I ASF+++   +  IR I
Sbjct: 203 NPAIIGNKKNMNLPGVKVDLPVIGEKDKNDILNFGIPMGCNFIAASFVQSADDVRYIRSI 262

Query: 199 LGEKGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARC 378
           LG KG+NIKII KIEN +G++N DEI+ E+DGIM+ARGDLG+EIPPEKVFLAQK MI++C
Sbjct: 263 LGTKGRNIKIIPKIENVEGLLNFDEILQEADGIMIARGDLGMEIPPEKVFLAQKMMISKC 322

Query: 379 NRVGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHT 558
           N  GKPVI ATQMLESM K PRPTRAE +DVANA+LDG DCVMLSGETA G +PV+ V  
Sbjct: 323 NVAGKPVITATQMLESMTKNPRPTRAEAADVANAVLDGTDCVMLSGETANGSFPVQAVTV 382

Query: 559 MANICKEAEAVIWHRQLFNDLVSEVKPPID 648
           M+ +C EAE  I ++Q+F         PID
Sbjct: 383 MSRVCFEAEGCIDYQQVFRATCQATMTPID 412


>UniRef50_Q42806 Cluster: Pyruvate kinase, cytosolic isozyme; n=62;
           Eukaryota|Rep: Pyruvate kinase, cytosolic isozyme -
           Glycine max (Soybean)
          Length = 511

 Score =  262 bits (641), Expect = 8e-69
 Identities = 126/235 (53%), Positives = 163/235 (69%), Gaps = 1/235 (0%)
 Frame = +1

Query: 19  DNAGMLGSRKGVNLPGIPVDLPAVSEKDKSDLL-FGVEQGVDMIFASFIRNGAALHEIRG 195
           +N   LG RK VNLPG+ VDLP ++EKDK D+L +GV   +DMI  SF+R G+ L  +R 
Sbjct: 168 ENTATLGERKNVNLPGVVVDLPTLTEKDKEDILGWGVPNKIDMIALSFVRKGSDLVNVRK 227

Query: 196 ILGEKGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIAR 375
           +LG   KNI+++SK+EN +G++N DEI+ E+D  MVARGDLG+EIP EK+FLAQK MI +
Sbjct: 228 VLGPHAKNIQLMSKVENQEGVLNFDEILRETDAFMVARGDLGMEIPVEKIFLAQKMMIYK 287

Query: 376 CNRVGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVH 555
           CN VGKPV+ ATQMLESM+K PRPTRAE +DVANA+LDG DCVMLSGE+A G YP   V 
Sbjct: 288 CNLVGKPVVTATQMLESMIKSPRPTRAEATDVANAVLDGTDCVMLSGESAAGAYPELAVK 347

Query: 556 TMANICKEAEAVIWHRQLFNDLVSEVKPPIDPXXXXXXXXXXXXTKCLASAIVVI 720
            MA IC EAE+ + +  +F +++     P+ P             K  A  IVV+
Sbjct: 348 IMARICIEAESSLDYGAIFKEMIRSTPLPMSPLESLASSAVRTANKAKAKLIVVL 402


>UniRef50_Q9KUN0 Cluster: Pyruvate kinase; n=24; cellular
           organisms|Rep: Pyruvate kinase - Vibrio cholerae
          Length = 470

 Score =  254 bits (622), Expect = 2e-66
 Identities = 125/192 (65%), Positives = 147/192 (76%), Gaps = 1/192 (0%)
 Frame = +1

Query: 22  NAGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGIL 201
           N G LG  KGVNLPG+ V+LPA+SEKDK+DL FG EQGVD + ASFIR G+ + EIR +L
Sbjct: 148 NNGALGENKGVNLPGVSVNLPALSEKDKNDLKFGCEQGVDFVAASFIRKGSDVKEIREVL 207

Query: 202 GEKG-KNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARC 378
              G +NI+IISKIEN +G+ N DEI+  SDGIMVARGDLG+EIP E+V  AQK MI +C
Sbjct: 208 ASHGGQNIQIISKIENQEGLDNFDEILELSDGIMVARGDLGVEIPAEEVIFAQKMMIEKC 267

Query: 379 NRVGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHT 558
           NR  K VI ATQML+SM+K PRPTRAE  DVANAI+DG D VMLSGETAKG YPVE V  
Sbjct: 268 NRARKVVITATQMLDSMIKNPRPTRAEAGDVANAIMDGTDAVMLSGETAKGKYPVEAVKI 327

Query: 559 MANICKEAEAVI 594
           MA I +  + V+
Sbjct: 328 MAQIAERTDPVL 339


>UniRef50_P52489 Cluster: Pyruvate kinase 2; n=33; Dikarya|Rep:
           Pyruvate kinase 2 - Saccharomyces cerevisiae (Baker's
           yeast)
          Length = 506

 Score =  254 bits (622), Expect = 2e-66
 Identities = 124/210 (59%), Positives = 149/210 (70%)
 Frame = +1

Query: 13  QQDNAGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIR 192
           Q  N+G + S KGVNLP   VDLP +S KD  DL FGV  G+ ++FASFIR    +  IR
Sbjct: 168 QAVNSGYIASHKGVNLPNTDVDLPPLSAKDMKDLQFGVRNGIHIVFASFIRTSEDVLSIR 227

Query: 193 GILGEKGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIA 372
             LG +G++IKIISKIEN QG+ N DEI+  +DG+M+ARGDLGIEI   +V   QK +IA
Sbjct: 228 KALGSEGQDIKIISKIENQQGLDNFDEILEVTDGVMIARGDLGIEILAPEVLAIQKKLIA 287

Query: 373 RCNRVGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECV 552
           +CN  GKPVICATQML+SM   PRPTRAE+SDV NA+LDGADCVMLSGETAKGDYPV  V
Sbjct: 288 KCNLAGKPVICATQMLDSMTHNPRPTRAEVSDVGNAVLDGADCVMLSGETAKGDYPVNAV 347

Query: 553 HTMANICKEAEAVIWHRQLFNDLVSEVKPP 642
           + MA     AE+ I H  L++DL      P
Sbjct: 348 NIMAATALIAESTIAHLALYDDLRDATPKP 377


>UniRef50_Q9M057 Cluster: Pyruvate kinase; n=11; Magnoliophyta|Rep:
           Pyruvate kinase - Arabidopsis thaliana (Mouse-ear cress)
          Length = 510

 Score =  254 bits (621), Expect = 2e-66
 Identities = 127/235 (54%), Positives = 162/235 (68%), Gaps = 1/235 (0%)
 Frame = +1

Query: 19  DNAGMLGSRKGVNLPGIPVDLPAVSEKDKSDLL-FGVEQGVDMIFASFIRNGAALHEIRG 195
           +N+ +LG RK VNLPGI VDLP ++EKDK D++ +GV   +D+I  SF+R G+ L E+R 
Sbjct: 163 ENSAILGERKNVNLPGIVVDLPTLTEKDKEDIIQWGVPNKIDIIALSFVRKGSDLTEVRR 222

Query: 196 ILGEKGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIAR 375
           +LGE  KNI ++SK+EN +G++N ++I+  SD  MVARGDLG+EIP EK+FLAQKTMI  
Sbjct: 223 LLGEHSKNIMLMSKVENQEGVMNCEKILENSDAFMVARGDLGMEIPIEKMFLAQKTMIKM 282

Query: 376 CNRVGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVH 555
            N +GKPV+ ATQMLESM   PRPTRAE +DVANA+LDG DCVMLSGETA G +P   V 
Sbjct: 283 ANALGKPVVTATQMLESMTVSPRPTRAEATDVANAVLDGTDCVMLSGETAAGAHPEAAVL 342

Query: 556 TMANICKEAEAVIWHRQLFNDLVSEVKPPIDPXXXXXXXXXXXXTKCLASAIVVI 720
           TM+ ICKEAE  I +  L    +  V  P+ P                ASAIVV+
Sbjct: 343 TMSRICKEAEDFIDYDILHKKTLGMVSLPLSPIESLAASVVSTAQSVFASAIVVL 397


>UniRef50_Q9VFG4 Cluster: Pyruvate kinase; n=3; Sophophora|Rep:
           Pyruvate kinase - Drosophila melanogaster (Fruit fly)
          Length = 1010

 Score =  246 bits (601), Expect = 6e-64
 Identities = 120/197 (60%), Positives = 151/197 (76%), Gaps = 2/197 (1%)
 Frame = +1

Query: 52  VNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGE--KGKNIK 225
           +N  G+  DL A++E+DK DL FG +Q VDMIFASFIR+  AL EIR  LG     ++IK
Sbjct: 259 INPQGVAADLNAITEQDKLDLKFGADQKVDMIFASFIRDAKALKEIRQALGACPSSEHIK 318

Query: 226 IISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVIC 405
           IISKIE+ Q + N+DEII ESDGIMVA G++G EI  E V LAQK+++A+CN+VGKPVIC
Sbjct: 319 IISKIESQQALANIDEIIRESDGIMVALGNMGNEIALEAVPLAQKSIVAKCNKVGKPVIC 378

Query: 406 ATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMANICKEAE 585
           A QM+ SM+ KPRPTRAE SDVANAILDG D ++LS ETAKG YPV+CV  MA IC + E
Sbjct: 379 ANQMMNSMITKPRPTRAESSDVANAILDGCDALVLSDETAKGKYPVQCVQCMARICAKVE 438

Query: 586 AVIWHRQLFNDLVSEVK 636
           +V+W+  + N+L SEV+
Sbjct: 439 SVLWYESIQNNLKSEVR 455


>UniRef50_P77983 Cluster: Pyruvate kinase I; n=29; Bacteria|Rep:
           Pyruvate kinase I - Salmonella typhimurium
          Length = 470

 Score =  244 bits (598), Expect = 1e-63
 Identities = 123/200 (61%), Positives = 148/200 (74%), Gaps = 1/200 (0%)
 Frame = +1

Query: 22  NAGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGIL 201
           N G LG  KGVNLPG+ + LPA++EKDK DL+FG EQGVD + ASFIR  + + EIR  L
Sbjct: 148 NNGDLGENKGVNLPGVSIALPALAEKDKQDLIFGCEQGVDFVAASFIRKRSDVVEIREHL 207

Query: 202 -GEKGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARC 378
               G+NI+IISKIEN +G+ N DEI+  SDGIMVARGDLG+EIP E+V  AQK MI +C
Sbjct: 208 KAHGGENIQIISKIENQEGLNNFDEILEASDGIMVARGDLGVEIPVEEVIFAQKMMIEKC 267

Query: 379 NRVGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHT 558
            R  K VI ATQML+SM+K PRPTRAE  DVANAILDG D VMLSGE+AKG YP+E V  
Sbjct: 268 IRARKVVITATQMLDSMIKNPRPTRAEAGDVANAILDGTDAVMLSGESAKGKYPLEAVSI 327

Query: 559 MANICKEAEAVIWHRQLFND 618
           MA IC+  + V+  R  +N+
Sbjct: 328 MATICERTDRVMNSRLDYNN 347


>UniRef50_Q22Z06 Cluster: Pyruvate kinase family protein; n=3;
           Oligohymenophorea|Rep: Pyruvate kinase family protein -
           Tetrahymena thermophila SB210
          Length = 505

 Score =  240 bits (587), Expect = 3e-62
 Identities = 114/198 (57%), Positives = 148/198 (74%), Gaps = 1/198 (0%)
 Frame = +1

Query: 22  NAGMLGSRKGVNLPGIPVDLPAVSEKDKSDLL-FGVEQGVDMIFASFIRNGAALHEIRGI 198
           N   +G +K +NLPG  VDLP V+EKD+ D++ FG++ G+D I  SF R    +  +R I
Sbjct: 171 NTCSIGEKKNMNLPGAIVDLPTVTEKDEDDIVNFGLKHGIDCIALSFARKAEDIEYVRDI 230

Query: 199 LGEKGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARC 378
           LG +G++IKII+KIEN +G+ N ++I+  +DGIMVARGDLG+EIPP+KVF+AQK MI + 
Sbjct: 231 LGPQGEHIKIIAKIENQEGLHNYEQILDAADGIMVARGDLGMEIPPQKVFVAQKWMIRKA 290

Query: 379 NRVGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHT 558
              GKP+I ATQM+ESM+K PRPTRAE SDVANA+LDG D VMLSGETA G +P++ V T
Sbjct: 291 LEKGKPIITATQMMESMIKNPRPTRAEASDVANAVLDGTDAVMLSGETANGSFPIQAVQT 350

Query: 559 MANICKEAEAVIWHRQLF 612
           MA IC EAE    +RQ F
Sbjct: 351 MAYICSEAELCYDNRQTF 368


>UniRef50_P80885 Cluster: Pyruvate kinase; n=161; Bacteria|Rep:
           Pyruvate kinase - Bacillus subtilis
          Length = 585

 Score =  236 bits (578), Expect = 3e-61
 Identities = 113/199 (56%), Positives = 148/199 (74%), Gaps = 1/199 (0%)
 Frame = +1

Query: 22  NAGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGIL 201
           N G L ++KGVN+PG+ V+LP ++EKD  D++FG+EQGVD I  SFIR    + EIR +L
Sbjct: 148 NNGTLKNKKGVNVPGVSVNLPGITEKDARDIVFGIEQGVDFIAPSFIRRSTDVLEIRELL 207

Query: 202 GE-KGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARC 378
            E   ++I+II KIEN +G+ N+D I+  SDG+MVARGDLG+EIP E+V L QK +I +C
Sbjct: 208 EEHNAQDIQIIPKIENQEGVDNIDAILEVSDGLMVARGDLGVEIPAEEVPLVQKELIKKC 267

Query: 379 NRVGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHT 558
           N +GKPVI ATQML+SM + PRPTRAE SDVANAI DG D +MLSGETA G YPVE V T
Sbjct: 268 NALGKPVITATQMLDSMQRNPRPTRAEASDVANAIFDGTDAIMLSGETAAGSYPVEAVQT 327

Query: 559 MANICKEAEAVIWHRQLFN 615
           M NI   +E  + ++++ +
Sbjct: 328 MHNIASRSEEALNYKEILS 346


>UniRef50_Q4U977 Cluster: Pyruvate kinase, putative; n=3;
           Piroplasmida|Rep: Pyruvate kinase, putative - Theileria
           annulata
          Length = 513

 Score =  234 bits (572), Expect = 2e-60
 Identities = 116/197 (58%), Positives = 142/197 (72%), Gaps = 1/197 (0%)
 Frame = +1

Query: 22  NAGMLGSRKGVNLPGIPVDLPAVSEKDKSDLL-FGVEQGVDMIFASFIRNGAALHEIRGI 198
           N   +G  K +NLPG+ V+LP ++E DK  +L FG+   +D I  SF +    +  +R +
Sbjct: 185 NNAKIGEYKNMNLPGVKVELPVLTESDKDYILNFGIPNQMDFIALSFTQTAEEVKYVREL 244

Query: 199 LGEKGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARC 378
           LGEKGK+IKII KIEN +G+ N DEI+  SDGIMVARGDLG+E+P EKV LAQK MI R 
Sbjct: 245 LGEKGKHIKIIPKIENIEGLANYDEILEASDGIMVARGDLGMEMPIEKVCLAQKMMIKRA 304

Query: 379 NRVGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHT 558
           N  GKP+I ATQMLESMV  PRPTRAE +DV NA+LDG+DCVMLSGETA G +PVECV  
Sbjct: 305 NMCGKPIITATQMLESMVNNPRPTRAESADVINAVLDGSDCVMLSGETAGGRFPVECVKI 364

Query: 559 MANICKEAEAVIWHRQL 609
           MA +C EAE  +  R L
Sbjct: 365 MAKLCFEAENCLSTRDL 381


>UniRef50_Q9VQH0 Cluster: Pyruvate kinase; n=3; Sophophora|Rep:
           Pyruvate kinase - Drosophila melanogaster (Fruit fly)
          Length = 554

 Score =  229 bits (561), Expect = 4e-59
 Identities = 109/233 (46%), Positives = 157/233 (67%)
 Frame = +1

Query: 22  NAGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGIL 201
           + G L +   V LP I +DLPAVSEKD  D+ F ++  VD +FAS +R+   + E+R +L
Sbjct: 184 HGGQLNNNCNVILPEIEIDLPAVSEKDMFDIQFSIKANVDFLFASAVRSAKNVKELRTVL 243

Query: 202 GEKGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCN 381
           GEKGK+IKII+K+++   +    EI+  +DG++++R DLG +IP EK+F+ QK+++ +CN
Sbjct: 244 GEKGKHIKIIAKMDSKIALSRFSEILRAADGLLLSRADLGTQIPIEKLFITQKSILGQCN 303

Query: 382 RVGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTM 561
           +VGKPVI A+ +LESM   P PTRAE  D+ANAI+DGADC+MLS E A G +P E V T 
Sbjct: 304 KVGKPVIVASHILESMRTLPHPTRAECFDLANAIIDGADCIMLSSEVAIGSFPKETVATC 363

Query: 562 ANICKEAEAVIWHRQLFNDLVSEVKPPIDPXXXXXXXXXXXXTKCLASAIVVI 720
             +C+EAE V+W R LF+DLVSEV+  +D              +  A+ I+V+
Sbjct: 364 DTLCREAEKVLWFRDLFSDLVSEVRGELDAAHSLAIAAVETAKRTNATLIIVL 416


>UniRef50_Q2TSW8 Cluster: Pyruvate kinase; n=4; stramenopiles|Rep:
           Pyruvate kinase - Phaeodactylum tricornutum
          Length = 543

 Score =  228 bits (558), Expect = 9e-59
 Identities = 117/207 (56%), Positives = 142/207 (68%), Gaps = 2/207 (0%)
 Frame = +1

Query: 19  DNAGMLGSRKGVNLPGIPVDLPAVSEKDKSDLL-FGVEQGVDMIFASFIRNGAALHEIRG 195
           DN   +G RK +NLPG+ VDLP  +EKD  D++ FG++  VD I ASF+R  + +  +R 
Sbjct: 179 DNNASMGERKNMNLPGVKVDLPTFTEKDVDDIVNFGIKHKVDFIAASFVRKQSDVANLRQ 238

Query: 196 ILGEKG-KNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIA 372
           +L E G + IKI  KIEN +G+ N D I+  +D IMVARGDLG+EIPP KVFLAQK MI 
Sbjct: 239 LLAENGGQQIKICCKIENQEGLENYDAILQATDSIMVARGDLGMEIPPAKVFLAQKMMIR 298

Query: 373 RCNRVGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECV 552
             N  GKPVI ATQMLESM+  PRPTRAE SDVANA+LDG DCVMLSGETA G Y  E V
Sbjct: 299 EANIAGKPVITATQMLESMINNPRPTRAECSDVANAVLDGTDCVMLSGETANGPYFEEAV 358

Query: 553 HTMANICKEAEAVIWHRQLFNDLVSEV 633
             MA  C EAE    +  L++ + S V
Sbjct: 359 KVMARTCCEAENSRNYNSLYSAVRSSV 385


>UniRef50_Q2TSW6 Cluster: Pyruvate kinase; n=1; Achlya
           bisexualis|Rep: Pyruvate kinase - Achlya bisexualis
           (Water mold)
          Length = 517

 Score =  227 bits (555), Expect = 2e-58
 Identities = 112/212 (52%), Positives = 149/212 (70%), Gaps = 8/212 (3%)
 Frame = +1

Query: 19  DNAGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGI 198
           +N+ +LGSRKGVNLPG+ VDLPA++ KDK D+ FGVE  +D I  SF+R    +++++  
Sbjct: 184 ENSEVLGSRKGVNLPGLVVDLPALTAKDKQDVEFGVEHDMDFIAVSFVRKPEDVNDVKDF 243

Query: 199 LGEKGKNI--------KIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLA 354
           +                IISKIEN++G+ N D I+  SDGIMVARGDLG+EIP ++V   
Sbjct: 244 VNSVMPKYWPAGHPAPLIISKIENYEGVSNFDRILEVSDGIMVARGDLGVEIPMQEVLTC 303

Query: 355 QKTMIARCNRVGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGD 534
           QK M+++CN  GKPVI ATQMLESM++ PRPTRAEI DV NA+LDGAD VMLSGE A+G 
Sbjct: 304 QKDMVSKCNAAGKPVIVATQMLESMIRNPRPTRAEILDVGNAVLDGADAVMLSGEVAQGK 363

Query: 535 YPVECVHTMANICKEAEAVIWHRQLFNDLVSE 630
           +PVE V TM ++ KEA+A +   Q   + +S+
Sbjct: 364 WPVESVKTMMSVIKEADAYVKREQYKKEALSQ 395


>UniRef50_P73534 Cluster: Pyruvate kinase 2; n=37; Bacteria|Rep:
           Pyruvate kinase 2 - Synechocystis sp. (strain PCC 6803)
          Length = 591

 Score =  219 bits (536), Expect = 4e-56
 Identities = 101/186 (54%), Positives = 137/186 (73%)
 Frame = +1

Query: 28  GMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGE 207
           G L S KGVN PG+ + + A+++KDK DL+FG++QGVD +  SF+RN   + EI+G++  
Sbjct: 158 GTLSSNKGVNFPGVCLSVKAMTDKDKEDLMFGLDQGVDWVALSFVRNPQDIDEIKGLIAA 217

Query: 208 KGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRV 387
            GK++ +I+KIE H+ + ++  ++ + DG+MVARGDLG+E+P E V + QK +IA  NR+
Sbjct: 218 AGKSVPVIAKIEKHEAIKDMQAVLEKCDGVMVARGDLGVELPAEDVPILQKKLIATANRL 277

Query: 388 GKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMAN 567
           G PVI ATQML+SMV  PRPTRAE+SDVANAILDG D VMLS ETA G +PVE V  MA 
Sbjct: 278 GIPVITATQMLDSMVNSPRPTRAEVSDVANAILDGTDAVMLSNETAIGKFPVEAVAIMAK 337

Query: 568 ICKEAE 585
           I +  E
Sbjct: 338 IAERIE 343


>UniRef50_UPI00006CE5D4 Cluster: pyruvate kinase family protein;
           n=1; Tetrahymena thermophila SB210|Rep: pyruvate kinase
           family protein - Tetrahymena thermophila SB210
          Length = 495

 Score =  217 bits (531), Expect = 2e-55
 Identities = 114/210 (54%), Positives = 144/210 (68%), Gaps = 19/210 (9%)
 Frame = +1

Query: 13  QQDNAGMLGSRKGVNLPGIPVDLPAVSEKD------KSDLLF-------------GVEQG 135
           Q +N G+L   K V LPG+ +DLP +SE+       K+D  F             G+E+G
Sbjct: 147 QFENEGILNEVKNVRLPGVKIDLPTISEEGIFIIQFKNDQQFQLILIDEDFIISQGLEKG 206

Query: 136 VDMIFASFIRNGAALHEIRGILGEKGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGD 315
           VD I  SF+R+G  +  +R +L  +G++IKII+KIEN +GM N ++I+  SDGIMVARGD
Sbjct: 207 VDFIAVSFVRSGEDIEYVRDLLSPRGEHIKIIAKIENIEGMENFEDILKSSDGIMVARGD 266

Query: 316 LGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMVKKPRPTRAEISDVANAILDGA 495
           LG+ IP +KVF+AQK MI RC  VGKPVI ATQM+ESMVK PRPTRAE SDVANA+LDG 
Sbjct: 267 LGMVIPAQKVFVAQKWMIDRCLEVGKPVITATQMMESMVKNPRPTRAEASDVANAVLDGT 326

Query: 496 DCVMLSGETAKGDYPVECVHTMANICKEAE 585
           D VMLS ET+ G YP ECV   + I +EAE
Sbjct: 327 DAVMLSTETSVGQYPCECVEITSQIAREAE 356


>UniRef50_A4E9R2 Cluster: Pyruvate kinase; n=1; Collinsella
           aerofaciens ATCC 25986|Rep: Pyruvate kinase -
           Collinsella aerofaciens ATCC 25986
          Length = 486

 Score =  217 bits (531), Expect = 2e-55
 Identities = 107/189 (56%), Positives = 137/189 (72%), Gaps = 1/189 (0%)
 Frame = +1

Query: 22  NAGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGIL 201
           N G++G RKGVN+P + + LPA++E+D+ D+LFG+ + +D I ASFIR+G ++  IR + 
Sbjct: 152 NDGLIGERKGVNMPNVNISLPAITERDRQDILFGLTENIDYIAASFIRDGESVRGIRELC 211

Query: 202 GEKG-KNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARC 378
            E G +++ I  KIE   G+ N DEI+  SDGIMVARGDLGIEI PE V   QK +IA+C
Sbjct: 212 RENGGEHVTIFPKIECALGVENFDEILEASDGIMVARGDLGIEIKPELVPHIQKEIIAKC 271

Query: 379 NRVGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHT 558
           N   KPVI ATQML+SM + PRPTRAE++DVANAI DG D VMLSGE+A G YPVE V  
Sbjct: 272 NAAYKPVITATQMLDSMQQNPRPTRAEVADVANAIYDGTDAVMLSGESAAGKYPVEAVKM 331

Query: 559 MANICKEAE 585
            A+I  E E
Sbjct: 332 QASIALETE 340


>UniRef50_Q55863 Cluster: Pyruvate kinase 1; n=5; Cyanobacteria|Rep:
           Pyruvate kinase 1 - Synechocystis sp. (strain PCC 6803)
          Length = 483

 Score =  214 bits (523), Expect = 2e-54
 Identities = 105/187 (56%), Positives = 137/187 (73%), Gaps = 1/187 (0%)
 Frame = +1

Query: 28  GMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGE 207
           G+L SRKGVNLPG+ + LP+++ KDK DL FG+ QG+D +  SF+R G  +H ++  L E
Sbjct: 163 GILKSRKGVNLPGLVLTLPSMTTKDKQDLEFGLSQGIDWVSLSFVRKGEDIHTLKQFLAE 222

Query: 208 KGK-NIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNR 384
           +G  ++ +I+KIE  Q + NL+EI+A S+GIMVARGDLG+E+ PEKV   QK +I RCN 
Sbjct: 223 RGHPDLPVIAKIEKPQAIDNLEEIVAVSNGIMVARGDLGVEVNPEKVPRLQKEIIRRCNV 282

Query: 385 VGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMA 564
              PVI ATQML+SM++  RPTRAE SDVANAILDG D VMLSGE+A G YPV+ V  + 
Sbjct: 283 RAIPVITATQMLDSMIQNSRPTRAEASDVANAILDGTDAVMLSGESAVGQYPVKSVQMLR 342

Query: 565 NICKEAE 585
            I +E E
Sbjct: 343 KIAEETE 349


>UniRef50_Q6AII5 Cluster: Pyruvate kinase; n=1; Desulfotalea
           psychrophila|Rep: Pyruvate kinase - Desulfotalea
           psychrophila
          Length = 581

 Score =  213 bits (519), Expect = 5e-54
 Identities = 108/206 (52%), Positives = 142/206 (68%)
 Frame = +1

Query: 28  GMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGE 207
           G+L SRK V LP   V+LP++SEKDK D+ FGVEQ VD I ASF+R    +  +R I+ +
Sbjct: 147 GILSSRKRVALPDNEVNLPSLSEKDKEDIAFGVEQDVDFIAASFVRQAGDVWAVRKIIED 206

Query: 208 KGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRV 387
            G + +II+KIEN QG+ NLDEI+  ++GIMVARGDLG+E+P E+V + QK++I   NR+
Sbjct: 207 NGGDQEIIAKIENRQGVNNLDEILQAANGIMVARGDLGVEVPAEEVPIIQKSIIKAANRL 266

Query: 388 GKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMAN 567
           GKPVI ATQMLESM+  P PTRAE +DV NAI DG D VMLSGETA G YPV+ V  +  
Sbjct: 267 GKPVITATQMLESMITCPTPTRAEANDVTNAIFDGTDAVMLSGETAIGKYPVQAVAFLVR 326

Query: 568 ICKEAEAVIWHRQLFNDLVSEVKPPI 645
               AE  + +  +  + +   +P I
Sbjct: 327 CATIAENALDYDHILANGLQNRRPTI 352


>UniRef50_Q64MR8 Cluster: Pyruvate kinase; n=6; Bacteroides|Rep:
           Pyruvate kinase - Bacteroides fragilis
          Length = 485

 Score =  212 bits (517), Expect = 9e-54
 Identities = 98/188 (52%), Positives = 138/188 (73%)
 Frame = +1

Query: 22  NAGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGIL 201
           N   LGSRK VN+PG+ ++LP+++EKD++++L+ +E+ +D I  SF+RN   + +IRGIL
Sbjct: 144 NEATLGSRKSVNVPGVRINLPSLTEKDRNNILYAIEKDIDFIAHSFVRNRQDVLDIRGIL 203

Query: 202 GEKGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCN 381
                +I+II+KIEN +G+ N+DEI+  +DG+MVARGDLGIE+P E++   Q+ +I +C 
Sbjct: 204 DAHNSDIRIIAKIENQEGVDNIDEILEVADGVMVARGDLGIEVPQERIPGIQRMLIRKCI 263

Query: 382 RVGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTM 561
              KPVI ATQML +M+  PRPTRAE++D+ANAI    D +MLSGETA G YPVE V TM
Sbjct: 264 LAKKPVIVATQMLHTMINNPRPTRAEVTDIANAIYYRTDALMLSGETAYGKYPVEAVKTM 323

Query: 562 ANICKEAE 585
             I  +AE
Sbjct: 324 TKIAAQAE 331


>UniRef50_Q1FK29 Cluster: Pyruvate kinase; n=4; Clostridiales|Rep:
           Pyruvate kinase - Clostridium phytofermentans ISDg
          Length = 580

 Score =  211 bits (516), Expect = 1e-53
 Identities = 109/209 (52%), Positives = 140/209 (66%), Gaps = 1/209 (0%)
 Frame = +1

Query: 22  NAGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGIL 201
           N GM+ + KGVN+PG+ + +P +S++D  D++FG+ QG D I ASF R    + +IR IL
Sbjct: 146 NGGMISNHKGVNVPGVELSMPFISKRDYEDIVFGIGQGFDFIAASFTRCADDIIQIRKIL 205

Query: 202 GEKGKN-IKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARC 378
            E   N + II+KIEN QG+ N+DEII  SDGIMVARGD+G+EIP E+V + QK +I + 
Sbjct: 206 NEYNCNTVNIIAKIENLQGVNNIDEIIRVSDGIMVARGDMGVEIPLEEVPVIQKMIIKKV 265

Query: 379 NRVGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHT 558
               K VI ATQML+SM+K PRPTRAE +DVANAI DG   +MLSGETA G YPVE + T
Sbjct: 266 YNAEKQVITATQMLDSMMKNPRPTRAEATDVANAIYDGTSAIMLSGETAAGLYPVEALRT 325

Query: 559 MANICKEAEAVIWHRQLFNDLVSEVKPPI 645
           M  I K  EA I +   F    S   P +
Sbjct: 326 MVKIAKRTEADIDYTSRFRKRDSLTNPDV 354


>UniRef50_A6DH47 Cluster: Pyruvate kinase; n=1; Lentisphaera
           araneosa HTCC2155|Rep: Pyruvate kinase - Lentisphaera
           araneosa HTCC2155
          Length = 485

 Score =  210 bits (513), Expect = 3e-53
 Identities = 105/188 (55%), Positives = 130/188 (69%), Gaps = 1/188 (0%)
 Frame = +1

Query: 25  AGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQ-GVDMIFASFIRNGAALHEIRGIL 201
           AG L S KG+NLP   +  PA++EKD+ DL F +E   +D +  SF+R G  L  I   +
Sbjct: 148 AGKLTSNKGINLPETDIQSPALTEKDERDLKFIIENDAIDFVALSFVRKGEDLDIIHAAM 207

Query: 202 GEKGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCN 381
            + GK   +ISKIE    +V++D II +SD +MVARGDLG+EIP EKV +AQKTMI +C 
Sbjct: 208 DKIGKRKPVISKIEKPSALVDIDAIIEKSDALMVARGDLGVEIPSEKVPVAQKTMIRKCI 267

Query: 382 RVGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTM 561
             GKP I ATQML+SM++ PRPTRAE SDVANA+LDGA  VMLSGETA G YPVE V  M
Sbjct: 268 EQGKPCIVATQMLDSMIRNPRPTRAEASDVANAVLDGASAVMLSGETASGSYPVEAVQMM 327

Query: 562 ANICKEAE 585
             I +E E
Sbjct: 328 TKIIRETE 335


>UniRef50_Q6MAN9 Cluster: Pyruvate kinase; n=1; Candidatus
           Protochlamydia amoebophila UWE25|Rep: Pyruvate kinase -
           Protochlamydia amoebophila (strain UWE25)
          Length = 598

 Score =  210 bits (512), Expect = 3e-53
 Identities = 104/191 (54%), Positives = 136/191 (71%), Gaps = 1/191 (0%)
 Frame = +1

Query: 19  DNAGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGI 198
           +N+GM+ S KGVN+P   ++LPAV+EKD  D+ FG  Q +D+I ASF+R+   + EI+ +
Sbjct: 147 NNSGMIRSSKGVNIPNTSLNLPAVTEKDIDDIRFGCSQDIDLIAASFVRSAEHVLEIKRL 206

Query: 199 LG-EKGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIAR 375
           L  EK  +I +I+KIEN +G+ N D I+  +DGIM+ARGDLG+E+P   V   QK MI +
Sbjct: 207 LADEKKTDILVIAKIENSEGVQNFDSIVQAADGIMIARGDLGVEVPLSHVPRLQKMMIRK 266

Query: 376 CNRVGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVH 555
               GKPV+ ATQMLESM+  PRPTRAE SDVANAI D    +MLSGETA G YPVE V+
Sbjct: 267 SYLAGKPVVTATQMLESMINNPRPTRAETSDVANAIYDSTSAIMLSGETAIGRYPVETVN 326

Query: 556 TMANICKEAEA 588
            M +I +EAEA
Sbjct: 327 VMRSIVEEAEA 337


>UniRef50_Q747D6 Cluster: Pyruvate kinase; n=6;
           Desulfuromonadales|Rep: Pyruvate kinase - Geobacter
           sulfurreducens
          Length = 480

 Score =  208 bits (509), Expect = 8e-53
 Identities = 102/186 (54%), Positives = 128/186 (68%)
 Frame = +1

Query: 28  GMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGE 207
           GML   KG+NLPG+ V  P++SEKD  DL F +E GVD I  SF+R  A +  ++ IL E
Sbjct: 152 GMLKDLKGINLPGVKVSAPSLSEKDLRDLDFCLEVGVDYIALSFVRTAADVEGLKRILFE 211

Query: 208 KGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRV 387
           +   + +++KIE  + + N   I+  +D +MVARGDLG+EI PEKV L QK +I  CN  
Sbjct: 212 RDVQVPVVAKIEKPEALRNFKSILKVADAVMVARGDLGVEISPEKVPLFQKKIIRACNEA 271

Query: 388 GKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMAN 567
           GKPVI ATQMLESM+  PRPTRAE SDVANAILDG D VMLSGETA G +P+E V TM  
Sbjct: 272 GKPVITATQMLESMISHPRPTRAETSDVANAILDGTDAVMLSGETASGQFPLEAVRTMDK 331

Query: 568 ICKEAE 585
           +  + E
Sbjct: 332 VALDVE 337


>UniRef50_A6LH43 Cluster: Pyruvate kinase; n=2; Parabacteroides|Rep:
           Pyruvate kinase - Parabacteroides distasonis (strain
           ATCC 8503 / DSM 20701 / NCTC11152)
          Length = 485

 Score =  208 bits (508), Expect = 1e-52
 Identities = 96/188 (51%), Positives = 138/188 (73%)
 Frame = +1

Query: 22  NAGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGIL 201
           N   LGSRK VN+PG+ ++LP+++EKD++++L+ ++  +D I  SF+RN   + +I+ IL
Sbjct: 145 NDATLGSRKSVNVPGVRINLPSLTEKDRNNILWAIDHDLDFIAHSFVRNKQDVLDIQRIL 204

Query: 202 GEKGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCN 381
            E+   IKII+KIEN +G+ N++EI+  + G+M+ARGDLGIE+P EK+   Q+ +I +C 
Sbjct: 205 DERNSPIKIIAKIENQEGVDNIEEILEVAYGVMIARGDLGIEVPAEKIPGIQRMLIRKCV 264

Query: 382 RVGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTM 561
            V KPVI ATQML SM+  PRPTRAE++D+ANAI    D +MLSGETA G YP+E V TM
Sbjct: 265 EVKKPVIVATQMLHSMINNPRPTRAEVTDIANAIYYRTDALMLSGETAYGKYPIEAVQTM 324

Query: 562 ANICKEAE 585
             + +EAE
Sbjct: 325 TKVAREAE 332


>UniRef50_Q8F253 Cluster: Pyruvate kinase; n=4; Leptospira|Rep:
           Pyruvate kinase - Leptospira interrogans
          Length = 478

 Score =  207 bits (506), Expect = 2e-52
 Identities = 103/188 (54%), Positives = 131/188 (69%)
 Frame = +1

Query: 28  GMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGE 207
           G+L S KG+NLPG P+  PA+SEKD  DL F +  GVD    SF+R GA L   R  L  
Sbjct: 157 GILWSNKGINLPGTPISAPALSEKDIEDLKFALSLGVDYAALSFVRTGADLELARSYL-- 214

Query: 208 KGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRV 387
           +G    +I+KIE  + + N++EII  +DGIM+ARGDLG+EI  EKV + QK +I + N+ 
Sbjct: 215 EGTYTGLIAKIERPEAIGNIEEIIERADGIMIARGDLGVEIDTEKVPILQKELIYKLNQA 274

Query: 388 GKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMAN 567
           GKPVI ATQMLESM++ PRPTRAE SDVANA++DG D VMLS E+A G YPVE V  M+ 
Sbjct: 275 GKPVITATQMLESMIENPRPTRAEASDVANAVMDGTDAVMLSAESANGHYPVESVEIMSK 334

Query: 568 ICKEAEAV 591
           I +E E +
Sbjct: 335 IIQETETI 342


>UniRef50_Q5V4I8 Cluster: Pyruvate kinase; n=4;
           Halobacteriaceae|Rep: Pyruvate kinase - Haloarcula
           marismortui (Halobacterium marismortui)
          Length = 610

 Score =  206 bits (504), Expect = 3e-52
 Identities = 102/193 (52%), Positives = 133/193 (68%)
 Frame = +1

Query: 7   FEQQDNAGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHE 186
           F   +N G L +RKGVN+PG+ +DLP ++E D+ +L    E+  D + ASF+R+G  ++E
Sbjct: 151 FATVENGGELAARKGVNVPGVELDLPTITENDEQELDVAAEKEPDFVAASFVRDGEDIYE 210

Query: 187 IRGILGEKGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTM 366
           I   L E+G +I II+KIE    + NLD II E+ G+MVARGDLG+E P E V + QK +
Sbjct: 211 ISQALEERGVDIPIIAKIERAGAVENLDSIIDEAYGVMVARGDLGVECPLEDVPIIQKRI 270

Query: 367 IARCNRVGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVE 546
           I RC+  G PVI AT+ML+SMV   RPTRAE SDVANA+LDG D VMLSGETA GD+P  
Sbjct: 271 IRRCHEAGVPVITATEMLDSMVHSRRPTRAEASDVANAVLDGTDAVMLSGETAIGDHPAR 330

Query: 547 CVHTMANICKEAE 585
            V TM  I ++ E
Sbjct: 331 VVETMDRIIRDVE 343


>UniRef50_Q2JLA2 Cluster: Pyruvate kinase; n=2; Synechococcus|Rep:
           Pyruvate kinase - Synechococcus sp. (strain
           JA-2-3B'a(2-13)) (Cyanobacteria bacteriumYellowstone
           B-Prime)
          Length = 619

 Score =  205 bits (501), Expect = 7e-52
 Identities = 106/194 (54%), Positives = 133/194 (68%), Gaps = 8/194 (4%)
 Frame = +1

Query: 28  GMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGIL-- 201
           G L + KGVN PG+ + + AV+ KDK DL FG+ QGVD +  SF+R+ + + E+R ++  
Sbjct: 156 GTLSNNKGVNFPGVRLSIRAVTPKDKEDLYFGLNQGVDWVALSFVRDPSDVLELRELIAS 215

Query: 202 ------GEKGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKT 363
                 G   K + II KIE H+ +  L +I+A SDG+MVARGDLG+E+P E+V + QK 
Sbjct: 216 AKRPSSGSADKRVPIIVKIEKHEAIEQLPQILALSDGVMVARGDLGVELPAEEVPILQKR 275

Query: 364 MIARCNRVGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPV 543
           +IA  N +G PVI ATQML+SMV  PRPTRAEISDVANAILDG D VMLS ETA G YPV
Sbjct: 276 VIALANSLGIPVITATQMLDSMVHSPRPTRAEISDVANAILDGTDAVMLSNETAVGKYPV 335

Query: 544 ECVHTMANICKEAE 585
           E V TMA I    E
Sbjct: 336 EAVATMARIAVRTE 349


>UniRef50_Q2IHE2 Cluster: Pyruvate kinase; n=1; Anaeromyxobacter
           dehalogenans 2CP-C|Rep: Pyruvate kinase -
           Anaeromyxobacter dehalogenans (strain 2CP-C)
          Length = 489

 Score =  205 bits (500), Expect = 1e-51
 Identities = 101/187 (54%), Positives = 130/187 (69%)
 Frame = +1

Query: 28  GMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGE 207
           G LG  KG+NLPG+ +   A+SEKD++D+ FG+  GVD +  SF+R    +   R  +  
Sbjct: 151 GWLGEHKGINLPGVALRAEALSEKDRADVAFGISHGVDYVALSFVRTPEDIALCRDEMER 210

Query: 208 KGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRV 387
            G+ + II+KIE  + + NLD IIA +DG+MVARGDLG+EI PE+V L QK + ++ N  
Sbjct: 211 AGRVVPIIAKIEKPEAIDNLDAIIAAADGVMVARGDLGVEILPERVPLLQKEICSKANAS 270

Query: 388 GKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMAN 567
           GKPVI ATQML SM++ PRPTRAE SDVAN I DGAD VMLSGETA G +P+  V  M  
Sbjct: 271 GKPVIIATQMLNSMIEHPRPTRAEASDVANGIWDGADAVMLSGETASGRFPLAAVQMMDR 330

Query: 568 ICKEAEA 588
           I +EAEA
Sbjct: 331 IVREAEA 337


>UniRef50_Q1Q4I4 Cluster: Strongly similar to pyruvate kinase; n=1;
           Candidatus Kuenenia stuttgartiensis|Rep: Strongly
           similar to pyruvate kinase - Candidatus Kuenenia
           stuttgartiensis
          Length = 472

 Score =  205 bits (500), Expect = 1e-51
 Identities = 99/186 (53%), Positives = 134/186 (72%)
 Frame = +1

Query: 28  GMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGE 207
           G+L SRKG+N+P   + + +++EKDK DL FG+EQGVD +  SF++    + E+R ++ +
Sbjct: 151 GVLTSRKGINIPARSLPVSSLTEKDKKDLEFGIEQGVDYVAMSFVKTAEDITELRDLIQK 210

Query: 208 KGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRV 387
           KGK I II+KIE H+ + N+++I+  +D IMVARGDLG+EIP E+V   QK +I   NR 
Sbjct: 211 KGKTIPIIAKIEKHEAVDNIEKIVNTADAIMVARGDLGVEIPLERVPSVQKMIIRLANRY 270

Query: 388 GKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMAN 567
           GKPVI ATQML SMV   RPTRAE++DVANAILDG+D VMLS E+A G YP + V  +  
Sbjct: 271 GKPVITATQMLASMVNNYRPTRAEVTDVANAILDGSDAVMLSEESAIGRYPADAVLMLTK 330

Query: 568 ICKEAE 585
           I K+ E
Sbjct: 331 IAKQIE 336


>UniRef50_Q1IHI1 Cluster: Pyruvate kinase; n=2; Bacteria|Rep:
           Pyruvate kinase - Acidobacteria bacterium (strain
           Ellin345)
          Length = 509

 Score =  205 bits (500), Expect = 1e-51
 Identities = 100/189 (52%), Positives = 129/189 (68%)
 Frame = +1

Query: 22  NAGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGIL 201
           N G L   +G+N+PG  + +PA++ KD  DL FG++ GVD +  SF+R    L ++R  +
Sbjct: 165 NGGELKEHQGINIPGAILSIPALTNKDLEDLAFGLKNGVDAVAISFVRTANDLKQVRNAI 224

Query: 202 GEKGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCN 381
            E   N+ +I+K+E  Q + +L+EI  E+DG+MVARGDLG+E+PPEKV + QK +I R  
Sbjct: 225 SEHQGNVFVIAKLEKPQAIEHLEEIFNETDGVMVARGDLGVEVPPEKVPVLQKHIIKRSQ 284

Query: 382 RVGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTM 561
               PVI ATQMLESM+  PRPTRAE SDVANAI DG D VMLSGETA G YP E V  M
Sbjct: 285 SRRIPVITATQMLESMIDNPRPTRAEASDVANAIFDGTDAVMLSGETASGKYPREAVAMM 344

Query: 562 ANICKEAEA 588
           A I  EAE+
Sbjct: 345 ARIITEAES 353


>UniRef50_A3I0G9 Cluster: Pyruvate kinase; n=3;
           Flexibacteraceae|Rep: Pyruvate kinase - Algoriphagus sp.
           PR1
          Length = 476

 Score =  204 bits (498), Expect = 2e-51
 Identities = 102/195 (52%), Positives = 135/195 (69%), Gaps = 2/195 (1%)
 Frame = +1

Query: 22  NAGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGIL 201
           + G+L SRKG+NLP   V  P+++EKD  DL FG+ + VD I  SF+R+   + ++R  +
Sbjct: 151 HGGILKSRKGINLPNTKVSAPSLTEKDIEDLAFGLSKEVDWIALSFVRSAEDIEDLRERI 210

Query: 202 GEKGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCN 381
             KGK+ KI++KIE  + + N+D II  +D IMVARGDLG+E+P E V L QK ++ +C 
Sbjct: 211 EAKGKHCKIVAKIEKPEALENIDGIIEATDAIMVARGDLGVEVPMEIVPLWQKRIVEKCK 270

Query: 382 RVGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTM 561
              KPVI ATQM+ESM+  PRPTRAE +DVANA+LDGAD VMLS ETA G YPV  V  M
Sbjct: 271 LACKPVIIATQMMESMIVNPRPTRAETNDVANAVLDGADAVMLSAETASGKYPVNAVKAM 330

Query: 562 ANIC--KEAEAVIWH 600
           ++I    EA A I+H
Sbjct: 331 SSIIGYLEANAEIYH 345


>UniRef50_Q8SQP0 Cluster: Pyruvate kinase; n=1; Encephalitozoon
           cuniculi|Rep: Pyruvate kinase - Encephalitozoon cuniculi
          Length = 519

 Score =  203 bits (495), Expect = 4e-51
 Identities = 99/188 (52%), Positives = 133/188 (70%)
 Frame = +1

Query: 22  NAGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGIL 201
           N+GM+ S K +N PG  +   A+ ++DK+D+ FG+E G+DM+FASF+   A + EIR ++
Sbjct: 235 NSGMIKSNKSMNFPGTDIGDRALGDEDKNDIAFGLENGIDMVFASFVSCRADVEEIRRLV 294

Query: 202 GEKGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCN 381
           G K   + ++SKIE+  GM NL EI   SDG+M+ARGDLG+EI  E +F AQK ++    
Sbjct: 295 GSK---VPVVSKIESCLGMRNLKEIALCSDGVMIARGDLGVEIGLENMFSAQKRILYEVK 351

Query: 382 RVGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTM 561
           R G+PVICATQM+ESM  K  P R+EISDV NA+LDG DCVMLS E+A G +PVE V  M
Sbjct: 352 REGRPVICATQMMESMTLKNAPNRSEISDVGNAVLDGCDCVMLSAESAVGMFPVETVKFM 411

Query: 562 ANICKEAE 585
            +IC +AE
Sbjct: 412 RSICADAE 419


>UniRef50_Q6A9P1 Cluster: Pyruvate kinase; n=4; Actinomycetales|Rep:
           Pyruvate kinase - Propionibacterium acnes
          Length = 477

 Score =  202 bits (493), Expect = 7e-51
 Identities = 95/188 (50%), Positives = 134/188 (71%)
 Frame = +1

Query: 25  AGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILG 204
           AG +G  KG+NLPG+ V +PA+++KD+ +L + ++ G+D++  SF+R+G+ +  +  I+ 
Sbjct: 153 AGPVGDHKGINLPGVAVSIPALTKKDEENLRWALKAGIDLVALSFVRHGSDIDRVHEIMD 212

Query: 205 EKGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNR 384
           E+G+ + +I+K+E  Q + NLDEII   D +MVARGD+ +E P E+V L QK +I +   
Sbjct: 213 EEGRTVPVIAKLEKPQAIENLDEIIDVFDAVMVARGDMAVECPLEEVPLIQKQIIEKARL 272

Query: 385 VGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMA 564
             KPVI ATQMLESM+  PRPTRAE +DVANAILDGAD VM S ET+ GD+P E V TMA
Sbjct: 273 QAKPVIVATQMLESMIHAPRPTRAEAADVANAILDGADGVMTSAETSVGDFPGETVRTMA 332

Query: 565 NICKEAEA 588
            I +  EA
Sbjct: 333 KIVESTEA 340


>UniRef50_Q4SVB7 Cluster: Pyruvate kinase; n=1; Tetraodon
           nigroviridis|Rep: Pyruvate kinase - Tetraodon
           nigroviridis (Green puffer)
          Length = 569

 Score =  202 bits (492), Expect = 9e-51
 Identities = 101/171 (59%), Positives = 119/171 (69%), Gaps = 1/171 (0%)
 Frame = +1

Query: 211 GKNIKIISKIENHQGM-VNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRV 387
           G+   ++     + G  + L + +  SDGIMVARGDLGIEIP EKVFLAQK MI RCNR 
Sbjct: 300 GRLSNLVCNCRRYSGFFLGLMKSMEASDGIMVARGDLGIEIPTEKVFLAQKMMIGRCNRA 359

Query: 388 GKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMAN 567
           GKP+ CATQMLESM+KKPRPTRAE SDVANA+LDGADC+MLSGETAKGDYP+E V T   
Sbjct: 360 GKPITCATQMLESMIKKPRPTRAEGSDVANAVLDGADCIMLSGETAKGDYPLEAVRTQHM 419

Query: 568 ICKEAEAVIWHRQLFNDLVSEVKPPIDPXXXXXXXXXXXXTKCLASAIVVI 720
           I +EAEA  +HRQLF +L    +   DP             KC ASA+VV+
Sbjct: 420 IAREAEAATFHRQLFEELRRHSQLTRDPSEAVAVGAVEASFKCCASALVVL 470



 Score =  126 bits (305), Expect = 4e-28
 Identities = 57/80 (71%), Positives = 68/80 (85%)
 Frame = +1

Query: 19  DNAGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGI 198
           +N G LGS+KGVNLPG  VDLPAVS+KD  DL FGVEQGVDM+FASFIR  A +H +R +
Sbjct: 203 ENGGTLGSKKGVNLPGAAVDLPAVSDKDVKDLQFGVEQGVDMVFASFIRKAADVHAVRAV 262

Query: 199 LGEKGKNIKIISKIENHQGM 258
           LGEKGK+IKIISK+ENH+G+
Sbjct: 263 LGEKGKDIKIISKLENHEGV 282


>UniRef50_Q6YQT6 Cluster: Pyruvate kinase; n=6; Candidatus
           Phytoplasma|Rep: Pyruvate kinase - Onion yellows
           phytoplasma
          Length = 446

 Score =  202 bits (492), Expect = 9e-51
 Identities = 104/197 (52%), Positives = 136/197 (69%), Gaps = 1/197 (0%)
 Frame = +1

Query: 22  NAGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGIL 201
           N   + SR+GVN+P + +++  +S KD  D++F  +Q  D I ASF+R    + +IR IL
Sbjct: 147 NTHSIKSRRGVNVPKVNLEMDFISPKDYQDIVFAAQQDFDYIAASFVRRAQDVKDIRKIL 206

Query: 202 GEKGK-NIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARC 378
            E+G  NI+IISKIEN +G+ NL+EII ESDGIMVARGDLGIE+  E V L Q  MI +C
Sbjct: 207 QEQGNSNIQIISKIENQEGVDNLEEIIQESDGIMVARGDLGIEVDGELVPLYQTRMITKC 266

Query: 379 NRVGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHT 558
              GKPV+ ATQMLESM + PRPT+AE SDV NA+ +G    MLSGE+A G+YPVE V  
Sbjct: 267 LEYGKPVVVATQMLESMQRNPRPTKAETSDVFNAVREGTTFTMLSGESASGEYPVEAVTY 326

Query: 559 MANICKEAEAVIWHRQL 609
           M  I  +AE V+ ++ L
Sbjct: 327 MKKINYQAEKVVNYQAL 343


>UniRef50_Q0W8N0 Cluster: Pyruvate kinase; n=7; cellular
           organisms|Rep: Pyruvate kinase - Uncultured methanogenic
           archaeon RC-I
          Length = 583

 Score =  201 bits (491), Expect = 1e-50
 Identities = 99/192 (51%), Positives = 134/192 (69%)
 Frame = +1

Query: 28  GMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGE 207
           G L S+KG+NLP   + +P+++EKD  DL FG+E  VDMI  SF+R    + ++R  + +
Sbjct: 147 GELKSKKGINLPQSTIRIPSITEKDVRDLEFGIEHEVDMIAMSFVRKPQDVLDLRKKIED 206

Query: 208 KGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRV 387
              +I IISKIE H+ + N+D II   DG+MVARGDLGIEIP  +V + QK +I++C   
Sbjct: 207 NDSDIPIISKIEKHEAVKNIDGIIDVVDGVMVARGDLGIEIPMAEVPIVQKMIISKCIAR 266

Query: 388 GKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMAN 567
           G PVI ATQML+SM++ P PTRAE +DVANA+ DG D +MLSGETA G+YPV+ V TMA 
Sbjct: 267 GIPVITATQMLDSMIRNPIPTRAEATDVANAVFDGTDALMLSGETAFGEYPVKAVETMAR 326

Query: 568 ICKEAEAVIWHR 603
           I K  E   +++
Sbjct: 327 IAKYTEESTYYK 338


>UniRef50_A6FYT4 Cluster: Pyruvate kinase; n=1; Plesiocystis
           pacifica SIR-1|Rep: Pyruvate kinase - Plesiocystis
           pacifica SIR-1
          Length = 485

 Score =  201 bits (490), Expect = 2e-50
 Identities = 100/190 (52%), Positives = 133/190 (70%), Gaps = 2/190 (1%)
 Frame = +1

Query: 22  NAGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGIL 201
           N G+L +RKGVNLP   + LP++++KD  DL F +E GVD +  SF+R    L E R I+
Sbjct: 152 NGGVLKARKGVNLPDSDLLLPSLTDKDAKDLRFALELGVDFVALSFVRRVEDLEECRKIM 211

Query: 202 GEKGKNIKIISKIENHQGMV--NLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIAR 375
            E G+ + +++KIE  + +   NL +I+  ++GIM+ARGDLG+E+ PE+V L QK +I  
Sbjct: 212 NEVGRTVPLVAKIEKPEALEPENLPKILDAANGIMIARGDLGVEMGPEEVPLIQKELIKL 271

Query: 376 CNRVGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVH 555
            N  GK VI ATQML+SM++ PRPTRAE SDVANAILDG+DCVMLSGETA G YP+  V 
Sbjct: 272 SNERGKLVITATQMLDSMIRNPRPTRAEASDVANAILDGSDCVMLSGETAAGKYPIRAVE 331

Query: 556 TMANICKEAE 585
           TM  I +  E
Sbjct: 332 TMDRIIRRIE 341


>UniRef50_Q07637 Cluster: Pyruvate kinase; n=44;
           Streptococcaceae|Rep: Pyruvate kinase - Lactococcus
           lactis subsp. lactis (Streptococcus lactis)
          Length = 502

 Score =  200 bits (488), Expect = 3e-50
 Identities = 96/197 (48%), Positives = 138/197 (70%), Gaps = 3/197 (1%)
 Frame = +1

Query: 13  QQDNAGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQ--GVDMIFASFIRNGAALHE 186
           +  N G++G +KGVN+P   +  PA++E+D +D+ FG+ Q  G++ I  SF+R    + E
Sbjct: 173 EAQNDGVIGKQKGVNIPNTKIPFPALAERDDADIRFGLSQPGGINFIAISFVRTANDVKE 232

Query: 187 IRGILGEKGK-NIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKT 363
           +R I  E G  ++++++KIEN QG+ NLDEII  +DGIM+ARGD+GIE+P E V + QK 
Sbjct: 233 VRRICEETGNPHVQLLAKIENQQGIENLDEIIEAADGIMIARGDMGIEVPFEMVPVYQKL 292

Query: 364 MIARCNRVGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPV 543
           +I++ N+ GK V+ AT MLESM   PR TR+EISDV NA++DG D  MLSGE+A G YP 
Sbjct: 293 IISKVNKAGKIVVTATNMLESMTYNPRATRSEISDVFNAVIDGTDATMLSGESANGKYPR 352

Query: 544 ECVHTMANICKEAEAVI 594
           E V TMA + K A+ ++
Sbjct: 353 ESVRTMATVNKNAQTML 369


>UniRef50_A6Q5W9 Cluster: Pyruvate kinase; n=2;
           Epsilonproteobacteria|Rep: Pyruvate kinase -
           Nitratiruptor sp. (strain SB155-2)
          Length = 458

 Score =  198 bits (484), Expect = 9e-50
 Identities = 97/190 (51%), Positives = 131/190 (68%)
 Frame = +1

Query: 22  NAGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGIL 201
           N G+L SRKGVN P   + L A++ KD+ DL FG ++GVD++  SF+ +   + + R IL
Sbjct: 140 NPGVLSSRKGVNFPHSNLRLSAITPKDEKDLRFGAKEGVDIVAISFVNSAQDIKKARSIL 199

Query: 202 GEKGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCN 381
            ++  N  I++KIE  + + NL+ I+  SDG+MVARGDLGIE+  EKV + QK +I   N
Sbjct: 200 AQEEANPWIVAKIETKKAVENLESILQASDGVMVARGDLGIEVGIEKVPVIQKRIIKEAN 259

Query: 382 RVGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTM 561
           R+GKPVI ATQML SMV  P PTRAE+SDVANA++DG+D VMLS ET  G YPVE V T+
Sbjct: 260 RLGKPVITATQMLLSMVNSPFPTRAEVSDVANAVIDGSDAVMLSDETTVGKYPVEAVQTL 319

Query: 562 ANICKEAEAV 591
             +  E  ++
Sbjct: 320 RKVIDETMSI 329


>UniRef50_Q8EX62 Cluster: Pyruvate kinase; n=5; Bacteria|Rep:
           Pyruvate kinase - Leptospira interrogans
          Length = 486

 Score =  198 bits (483), Expect = 1e-49
 Identities = 91/188 (48%), Positives = 134/188 (71%)
 Frame = +1

Query: 22  NAGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGIL 201
           + G LGSRK +NLPGI V+LP+++ KD  D+LFG+E+ VD I  SF+R+   +++++ I+
Sbjct: 155 DGGRLGSRKHINLPGIRVNLPSITPKDHKDILFGLEEDVDFIALSFVRSVEDINQLKQII 214

Query: 202 GEKGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCN 381
            E   + +II+KIE+ + + N+ EI+  +DG+MVARGDLG+E+P E++ + Q+ +I  C 
Sbjct: 215 EENDGHAQIIAKIEDQEAVRNMKEIVEAADGVMVARGDLGVEVPIEELPILQRAIIKECA 274

Query: 382 RVGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTM 561
             GK VI AT +LESM+  P PTRAE++DVANAI + AD +MLSGETA G +P+ CV  M
Sbjct: 275 LKGKRVIVATHLLESMIHNPSPTRAEVTDVANAIYEEADAIMLSGETAAGKFPIRCVEMM 334

Query: 562 ANICKEAE 585
             I +  E
Sbjct: 335 DKIAQRVE 342


>UniRef50_A6PUS2 Cluster: Pyruvate kinase; n=1; Victivallis vadensis
           ATCC BAA-548|Rep: Pyruvate kinase - Victivallis vadensis
           ATCC BAA-548
          Length = 357

 Score =  198 bits (482), Expect = 1e-49
 Identities = 99/186 (53%), Positives = 129/186 (69%)
 Frame = +1

Query: 28  GMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGE 207
           G L + K VN+PG  + +PA++ KD+  + + V+  +D I  SF+R+   +  +R IL  
Sbjct: 32  GELKNHKSVNVPGAELKMPALTRKDRDFIEYAVKNDLDFIAHSFVRSANDVLAVRSILDT 91

Query: 208 KGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRV 387
              +I+II+KIEN QG+ NLDEI+  +DG+MVARGDLGIEIP E+V L QK +I  C   
Sbjct: 92  GDSDIRIIAKIENRQGVDNLDEILKAADGVMVARGDLGIEIPLEEVPLIQKKLIRACMAA 151

Query: 388 GKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMAN 567
           GK VI ATQML+SM   P PTRAEI+DVANA+ DG D VMLSGETA+G YPVE V  M+ 
Sbjct: 152 GKSVITATQMLQSMENSPLPTRAEINDVANAVYDGTDAVMLSGETAEGVYPVEAVSVMSR 211

Query: 568 ICKEAE 585
           I +E E
Sbjct: 212 ILEETE 217


>UniRef50_Q7UF82 Cluster: Pyruvate kinase; n=1; Pirellula sp.|Rep:
           Pyruvate kinase - Rhodopirellula baltica
          Length = 476

 Score =  197 bits (481), Expect = 2e-49
 Identities = 98/199 (49%), Positives = 134/199 (67%)
 Frame = +1

Query: 28  GMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGE 207
           G+L SR+ +NLPG+ V+LPA+++KD++DL  GV+ G+D +  SF+R    +  +R  L E
Sbjct: 157 GVLESRRHINLPGVQVNLPAITDKDRTDLAAGVKAGIDFVALSFVRQAEDVRTLRAFLDE 216

Query: 208 KGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRV 387
            G   +IISKIE+  G+ N+  II +SD IMVARGDLG+EI   ++ L Q  +I  C   
Sbjct: 217 HGSPARIISKIEDQAGVRNMKAIIRQSDAIMVARGDLGVEIDYHRLPLVQTDLIRACQED 276

Query: 388 GKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMAN 567
           GKPVI AT +LESM++ P PTRAE+SDV+NAI + AD VMLSGET  G YP+E V  + N
Sbjct: 277 GKPVIIATHLLESMIQSPVPTRAEVSDVSNAIREQADAVMLSGETTTGKYPLESVGVLQN 336

Query: 568 ICKEAEAVIWHRQLFNDLV 624
           I    E  +  RQL + +V
Sbjct: 337 IVASIEPTV-SRQLNSKIV 354


>UniRef50_Q1AXJ8 Cluster: Pyruvate kinase; n=1; Rubrobacter
           xylanophilus DSM 9941|Rep: Pyruvate kinase - Rubrobacter
           xylanophilus (strain DSM 9941 / NBRC 16129)
          Length = 477

 Score =  197 bits (480), Expect = 3e-49
 Identities = 94/190 (49%), Positives = 131/190 (68%), Gaps = 1/190 (0%)
 Frame = +1

Query: 28  GMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQ-GVDMIFASFIRNGAALHEIRGILG 204
           G + S KG+N P   + +  ++EKD  DL FG+E+   D +  SF+R G  + +++  + 
Sbjct: 150 GPVSSHKGLNFPDSSLSISGLTEKDLEDLRFGLEELRPDWVAISFVRTGEEVLDVKERIR 209

Query: 205 EKGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNR 384
           E G ++ +ISKIE H+ + N++E+I  SDG+MVARGDL +E+  E+V + QK ++ARC R
Sbjct: 210 ELGGDVPVISKIEKHEAIDNIEEVIEASDGVMVARGDLAVELSAERVPIEQKRIVARCRR 269

Query: 385 VGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMA 564
            G+PVI ATQML+SM++ PRPTRAE+SDVANAI D  D VMLSGETA G YP + V  M 
Sbjct: 270 RGRPVIVATQMLDSMMRNPRPTRAEVSDVANAIFDRTDAVMLSGETAVGRYPTQSVMEMD 329

Query: 565 NICKEAEAVI 594
            IC+ AE  I
Sbjct: 330 RICRAAEGAI 339


>UniRef50_Q2S3S2 Cluster: Pyruvate kinase; n=1; Salinibacter ruber
           DSM 13855|Rep: Pyruvate kinase - Salinibacter ruber
           (strain DSM 13855)
          Length = 476

 Score =  196 bits (478), Expect = 5e-49
 Identities = 100/193 (51%), Positives = 130/193 (67%)
 Frame = +1

Query: 28  GMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGE 207
           G L SRKGVNLP +    P ++EKD  DL  G+E  VD++  SF++  + +  +   + E
Sbjct: 150 GPLRSRKGVNLPDLQASTPPMTEKDLKDLELGLELEVDVVALSFVQERSDVEALVHRIEE 209

Query: 208 KGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRV 387
            GK   +++KIE  Q + N+DEI+   DGIMVARGDLGIE+P E+V   QK +I +    
Sbjct: 210 TGKKTSVVAKIEKPQAVHNIDEILEVVDGIMVARGDLGIEMPMEEVPGTQKRLIRKSMEA 269

Query: 388 GKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMAN 567
            KPVI ATQMLESMV+ PRPTRAE SDVANA+LDG+D VMLS ETA GD+PV  V  M  
Sbjct: 270 AKPVITATQMLESMVEDPRPTRAEASDVANAVLDGSDAVMLSAETAVGDHPVRVVEAMNQ 329

Query: 568 ICKEAEAVIWHRQ 606
           I ++AE+  WH +
Sbjct: 330 IIRQAES-YWHEE 341


>UniRef50_A7CUA8 Cluster: Pyruvate kinase; n=1; Opitutaceae
           bacterium TAV2|Rep: Pyruvate kinase - Opitutaceae
           bacterium TAV2
          Length = 480

 Score =  196 bits (478), Expect = 5e-49
 Identities = 93/187 (49%), Positives = 128/187 (68%)
 Frame = +1

Query: 28  GMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGE 207
           G L SR+ +NLPG+ V+LP+++EKDK+DL  G+ +G+D +  SF+R  A +  +R +L  
Sbjct: 161 GELKSRRHINLPGVKVNLPSLTEKDKTDLAVGLIEGIDFVALSFVREAADIQLLRDVLHR 220

Query: 208 KGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRV 387
                 II+KIE+   + NLDEI+  +D +MVARGDLGIE P E++ + Q+  +  C   
Sbjct: 221 YKSRAGIIAKIEDQSAIANLDEIVRTTDALMVARGDLGIECPFEELPIIQRRAVRMCFDY 280

Query: 388 GKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMAN 567
           GKPVI AT MLESM+  P PTRAEI+DVANA+ + ADCVMLSGET  G YP+ECV  +  
Sbjct: 281 GKPVIIATHMLESMIASPMPTRAEITDVANAVYEKADCVMLSGETTIGRYPLECVQILDK 340

Query: 568 ICKEAEA 588
           I +  E+
Sbjct: 341 IARRIES 347


>UniRef50_Q8YTZ8 Cluster: Pyruvate kinase; n=3; Nostocaceae|Rep:
           Pyruvate kinase - Anabaena sp. (strain PCC 7120)
          Length = 476

 Score =  196 bits (477), Expect = 6e-49
 Identities = 95/186 (51%), Positives = 127/186 (68%)
 Frame = +1

Query: 28  GMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGE 207
           G+L +RKGVNLP   + + +++EKD  DL FG++  VD +  SF+R+   L   + ++  
Sbjct: 148 GLLSTRKGVNLPATRLPVSSITEKDLQDLRFGIDLSVDWVAVSFVRSPYDLEPAQRMIEA 207

Query: 208 KGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRV 387
            GK I++I+KIE  + +  +D II  +D IM+ARGDLG+E+P  +V L QK +I RCN+ 
Sbjct: 208 AGKTIRVIAKIERPEAVEQIDSIIDVADAIMIARGDLGVEMPIHEVPLIQKDIIRRCNQA 267

Query: 388 GKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMAN 567
           GKPVI ATQMLESM+  P PTRAE +DVAN+ILDG D VMLSGETA G YPV  V  M +
Sbjct: 268 GKPVITATQMLESMISAPDPTRAEATDVANSILDGTDAVMLSGETAVGQYPVAAVQVMHD 327

Query: 568 ICKEAE 585
           I    E
Sbjct: 328 IAVTTE 333


>UniRef50_A7HIL5 Cluster: Pyruvate kinase; n=9; Bacteria|Rep:
           Pyruvate kinase - Anaeromyxobacter sp. Fw109-5
          Length = 491

 Score =  196 bits (477), Expect = 6e-49
 Identities = 94/186 (50%), Positives = 128/186 (68%)
 Frame = +1

Query: 28  GMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGE 207
           G+L   KG+NLPG+ +   A+SEKD++D+ FG+  GVD +  SF+R+   +   R  +  
Sbjct: 154 GVLREHKGINLPGVALRAEALSEKDRADIAFGLAHGVDAVALSFVRSAEDIRACRDEMER 213

Query: 208 KGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRV 387
            G+ + +I+KIE  + +  +D II  +DGIM+ARGDLG+EI PE+V L QK +  R N  
Sbjct: 214 VGRVVPVIAKIEKPEALDAIDAIIEAADGIMIARGDLGVEILPERVPLLQKDICRRGNAA 273

Query: 388 GKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMAN 567
           GKPV+ ATQMLESM++ PRPTRAE SDVANA+ DGAD VMLS E+A G +P+  V  M  
Sbjct: 274 GKPVVIATQMLESMIEHPRPTRAEASDVANAVWDGADAVMLSAESASGRFPLNAVQMMDR 333

Query: 568 ICKEAE 585
           I +EAE
Sbjct: 334 IVREAE 339


>UniRef50_Q6F1U1 Cluster: Pyruvate kinase; n=10; Mollicutes|Rep:
           Pyruvate kinase - Mesoplasma florum (Acholeplasma
           florum)
          Length = 478

 Score =  194 bits (474), Expect = 1e-48
 Identities = 102/206 (49%), Positives = 135/206 (65%), Gaps = 1/206 (0%)
 Frame = +1

Query: 22  NAGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGIL 201
           N  ++ + K VNLPG+   +P +++KD +D+ +GVEQGVD I ASF+ +   + EIR IL
Sbjct: 159 NNHLVKTNKRVNLPGVDFSMPFLAQKDINDIKYGVEQGVDYIAASFVNSAENVKEIRDIL 218

Query: 202 GE-KGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARC 378
            E  G +I+IISKIE+  G+ N+D II  SDGIM+ARGDLG+EIP   V   +K MI +C
Sbjct: 219 AEANGSDIQIISKIESQVGIDNIDAIIEASDGIMIARGDLGLEIPYYDVPYWEKIMIRKC 278

Query: 379 NRVGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHT 558
              GK VI ATQMLE+M + P PTRAE++DV  A   GAD  MLSGE+A GDYP   V+T
Sbjct: 279 REAGKVVIVATQMLETMTENPAPTRAEVTDVYFATELGADATMLSGESAAGDYPFITVNT 338

Query: 559 MANICKEAEAVIWHRQLFNDLVSEVK 636
           MA I K AE   + +  +   +   K
Sbjct: 339 MATINKRAEIEFYKKAYYQTQLENAK 364


>UniRef50_Q08SK3 Cluster: Pyruvate kinase; n=2;
           Cystobacterineae|Rep: Pyruvate kinase - Stigmatella
           aurantiaca DW4/3-1
          Length = 481

 Score =  194 bits (472), Expect = 2e-48
 Identities = 98/186 (52%), Positives = 126/186 (67%)
 Frame = +1

Query: 28  GMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGE 207
           G+L   KG+NLPG  + +P ++EKD  DL FG E GVD +  SF+R    +H+ R  + +
Sbjct: 163 GLLKDHKGLNLPGAAISVPTITEKDAEDLAFGQELGVDYVALSFVRTANDIHQARTHVSK 222

Query: 208 KGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRV 387
                 +I+KIE  Q + NL+ I   +DG+MVARGDLG+E+P E++   QK M+A  NR 
Sbjct: 223 L--KTPLIAKIEKPQALENLEAISEAADGVMVARGDLGVEMPLEQLPGIQKRMVAEVNRK 280

Query: 388 GKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMAN 567
           G  VI AT+MLESMV   RPTRAE+SDVANAILDGAD VMLSGETA G YP++   TMA 
Sbjct: 281 GGLVIVATEMLESMVGNARPTRAEVSDVANAILDGADAVMLSGETAAGKYPIDAAATMAR 340

Query: 568 ICKEAE 585
           I +E E
Sbjct: 341 IVEETE 346


>UniRef50_Q9RR62 Cluster: Pyruvate kinase; n=5; Bacteria|Rep:
           Pyruvate kinase - Deinococcus radiodurans
          Length = 482

 Score =  192 bits (469), Expect = 6e-48
 Identities = 100/207 (48%), Positives = 130/207 (62%)
 Frame = +1

Query: 28  GMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGE 207
           G L + KG+N+P   + +PA+SEKD  D+ FG   GVD +  SF+R+   L   R  L  
Sbjct: 152 GTLKNNKGINVPEADLTVPALSEKDVQDMEFGASLGVDWVALSFVRSRDDLLLARHYLAR 211

Query: 208 KGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRV 387
            G   K+++KIE  Q +    +I+ E DG+MVARGDLG+E+ PE+V   QK +I  C   
Sbjct: 212 FGSRAKLMAKIEKPQAVDRFADILKEVDGVMVARGDLGVEMRPEQVPTIQKRIIRMCREA 271

Query: 388 GKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMAN 567
           GKPVI ATQMLESM+  PRPTRAE SDVANAI DG D VMLS E+A G YPVE V  M  
Sbjct: 272 GKPVITATQMLESMINLPRPTRAEASDVANAIYDGTDAVMLSAESAAGQYPVESVAMMDR 331

Query: 568 ICKEAEAVIWHRQLFNDLVSEVKPPID 648
           I +EAEA   ++ +   +V + +   D
Sbjct: 332 IAREAEASELYQLMQRQVVMDTEQAQD 358


>UniRef50_O51323 Cluster: Pyruvate kinase; n=5; cellular
           organisms|Rep: Pyruvate kinase - Borrelia burgdorferi
           (Lyme disease spirochete)
          Length = 477

 Score =  192 bits (469), Expect = 6e-48
 Identities = 94/189 (49%), Positives = 130/189 (68%), Gaps = 1/189 (0%)
 Frame = +1

Query: 22  NAGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGIL 201
           N G + ++K +N PGI + L +V+EKDK  +    +  VD I  SF+R+   + +++ IL
Sbjct: 142 NDGQIKNKKSINTPGISLKLQSVTEKDKGFIELAAKYNVDFIAHSFVRHSKDVQDVQEIL 201

Query: 202 GEKGK-NIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARC 378
              G  ++KIISKIEN +G+ N++EI   S GIMVARGD+G+EIP E V +AQ  +   C
Sbjct: 202 TASGNPDVKIISKIENQEGIDNIEEIAKASYGIMVARGDMGVEIPAEDVPIAQLKITQTC 261

Query: 379 NRVGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHT 558
            + G PVI ATQML +M++ PRPTRAE+SD+ANAIL+G D +MLSGETA G YP+E V  
Sbjct: 262 IKYGIPVITATQMLHTMIENPRPTRAEVSDIANAILNGTDAIMLSGETAYGKYPIEAVKM 321

Query: 559 MANICKEAE 585
           M +I K+ E
Sbjct: 322 MTSIAKKVE 330


>UniRef50_Q1MPC8 Cluster: Pyruvate kinase; n=4;
           Desulfovibrionaceae|Rep: Pyruvate kinase - Lawsonia
           intracellularis (strain PHE/MN1-00)
          Length = 471

 Score =  192 bits (468), Expect = 7e-48
 Identities = 96/189 (50%), Positives = 133/189 (70%)
 Frame = +1

Query: 28  GMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGE 207
           G++ SRKG+ LPG  + +PA++EKD+ DL  G++ GVD +  SF+++   + E + I+  
Sbjct: 150 GIITSRKGLALPGKSIKVPAITEKDQKDLSDGLKLGVDAVAISFVQSAEDIIEAKRIIKA 209

Query: 208 KGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRV 387
            G +I +I+K+E    + +L+EI+ E D IMVARGDLGIE P  ++   QK +I  CN+ 
Sbjct: 210 NGYDIPVIAKLERRNAIEHLEEILKEVDIIMVARGDLGIECPLPELPAIQKRIIRACNKA 269

Query: 388 GKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMAN 567
            KPVI ATQML SMV  P PTRAEI+DVANA+LDGADCVMLS ETA G++PVE V  M +
Sbjct: 270 SKPVIVATQMLLSMVSNPTPTRAEITDVANAVLDGADCVMLSEETAMGNHPVETVGFMRD 329

Query: 568 ICKEAEAVI 594
           I  +AE ++
Sbjct: 330 ITTKAEELM 338


>UniRef50_Q3JCE7 Cluster: Pyruvate kinase; n=1; Nitrosococcus oceani
           ATCC 19707|Rep: Pyruvate kinase - Nitrosococcus oceani
           (strain ATCC 19707 / NCIMB 11848)
          Length = 492

 Score =  191 bits (466), Expect = 1e-47
 Identities = 98/187 (52%), Positives = 128/187 (68%), Gaps = 1/187 (0%)
 Frame = +1

Query: 28  GMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGE 207
           G L SRKGV  P   +  P ++EKD +D  FGV   VDM+  SF+R+   + E+R  L E
Sbjct: 170 GQLRSRKGVIFPDSQLSFPLLNEKDATDARFGVFLDVDMVAMSFVRSATEIIEMRLRLAE 229

Query: 208 KG-KNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNR 384
            G KN  II+KIE+H+G+ NLDEI+  +DG++VARGDLG+ +P EKV   QK +I + N 
Sbjct: 230 WGQKNSFIIAKIEDHKGIDNLDEILQVADGVLVARGDLGVTLPREKVPNIQKAIIQKANA 289

Query: 385 VGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMA 564
            G PVI ATQMLESM     PTRAE++DV +A++ G+D VMLSGETA G YP++ V  M 
Sbjct: 290 FGVPVITATQMLESMTHHDIPTRAEVNDVYHAVIGGSDAVMLSGETASGRYPIQAVQEMN 349

Query: 565 NICKEAE 585
            IC+EAE
Sbjct: 350 RICREAE 356


>UniRef50_Q6MLB5 Cluster: Pyruvate kinase; n=1; Bdellovibrio
           bacteriovorus|Rep: Pyruvate kinase - Bdellovibrio
           bacteriovorus
          Length = 495

 Score =  191 bits (465), Expect = 2e-47
 Identities = 91/186 (48%), Positives = 128/186 (68%)
 Frame = +1

Query: 28  GMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGE 207
           G+L  RKG+NLPG+ + +  ++ KD  DL FG+   VD I  SF+R+   + ++R ++  
Sbjct: 151 GILKDRKGMNLPGVNLPVDCMTPKDLEDLQFGIANKVDYIALSFVRHARDIRKLRELIEA 210

Query: 208 KGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRV 387
              N KI++KIE  + + NL+EI   SD +MVARGDL +E+   ++   QK +I+ CN++
Sbjct: 211 GNSNAKIVAKIEMVEAIENLEEICRLSDAVMVARGDLAVEVGQSRLPGYQKRIISVCNQL 270

Query: 388 GKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMAN 567
           GKPVI ATQML+SMV+ PRPTRAEI+DVANA+LDG D +MLS E+A G YP +C+ TM  
Sbjct: 271 GKPVITATQMLDSMVENPRPTRAEITDVANAVLDGTDALMLSAESASGKYPFKCIRTMHE 330

Query: 568 ICKEAE 585
           I  E E
Sbjct: 331 IITEVE 336


>UniRef50_Q1K4D5 Cluster: Pyruvate kinase; n=1; Desulfuromonas
           acetoxidans DSM 684|Rep: Pyruvate kinase -
           Desulfuromonas acetoxidans DSM 684
          Length = 474

 Score =  191 bits (465), Expect = 2e-47
 Identities = 93/188 (49%), Positives = 127/188 (67%)
 Frame = +1

Query: 22  NAGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGIL 201
           + G+  SRKGVN+P   + +PA +EKD+ DL FG++QGVD++  SF+R    L EIR +L
Sbjct: 145 SGGVAYSRKGVNMPSSHLSIPAFTEKDRDDLRFGLQQGVDIVALSFVRGADDLKEIRTML 204

Query: 202 GEKGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCN 381
            E  +  K+++KIE  Q + +++EI+   D +M+ARGDLG+E+P E+V + QK +I +  
Sbjct: 205 AEVPEAPKLVAKIEKPQAVAHIEEILDVVDVVMIARGDLGVEVPLEQVPVLQKQLIHKAR 264

Query: 382 RVGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTM 561
             GK VI ATQML SMV  PRPTRAE +DVANAI DG D +MLS ETA GDYPV     +
Sbjct: 265 LKGKAVITATQMLSSMVSNPRPTRAEAADVANAIYDGTDALMLSDETASGDYPVAATRML 324

Query: 562 ANICKEAE 585
             I +  E
Sbjct: 325 DRIARSTE 332


>UniRef50_Q6KHW9 Cluster: Pyruvate kinase; n=3; Mycoplasma|Rep:
           Pyruvate kinase - Mycoplasma mobile
          Length = 483

 Score =  190 bits (464), Expect = 2e-47
 Identities = 97/195 (49%), Positives = 138/195 (70%), Gaps = 1/195 (0%)
 Frame = +1

Query: 22  NAGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGIL 201
           N+ +L S K +N+PG  + L  +S+KDK D++FG++  V+ I ASF+ +   + ++R +L
Sbjct: 163 NSHVLKSNKRINIPGAQLSLEFLSKKDKEDIIFGIKNDVNYIAASFVNSKQDVLDLRKLL 222

Query: 202 GEK-GKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARC 378
            +  G++I+IISKIE+  G+ N+DEII  SDGIM+ARGDLG+EIP  +V   +K +I +C
Sbjct: 223 KDNNGEHIQIISKIESVFGIENIDEIIEASDGIMIARGDLGLEIPYFEVPFYEKQIIRKC 282

Query: 379 NRVGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHT 558
             VGKPVI ATQML+SM K P+PTRAE+SDV  A   GAD  MLSGE+A GD+PVE V  
Sbjct: 283 RNVGKPVIVATQMLDSMEKLPQPTRAEVSDVYWATELGADATMLSGESANGDFPVESVEV 342

Query: 559 MANICKEAEAVIWHR 603
           M+ I + AE   +++
Sbjct: 343 MSTINRRAEKEFYNK 357


>UniRef50_A4MK73 Cluster: Pyruvate kinase; n=1; Petrotoga mobilis
           SJ95|Rep: Pyruvate kinase - Petrotoga mobilis SJ95
          Length = 478

 Score =  190 bits (464), Expect = 2e-47
 Identities = 98/190 (51%), Positives = 126/190 (66%), Gaps = 1/190 (0%)
 Frame = +1

Query: 28  GMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGE 207
           G +  R+G+N+PGI + LP ++EKD   L   VE  VD I  SF+R    +   R IL E
Sbjct: 154 GSITHRRGINVPGIDISLPPLTEKDMEYLNKAVEWNVDYIAQSFVRKAEDITRTRRILTE 213

Query: 208 KGK-NIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNR 384
            G  ++ II+KIE  Q + NL+ II E+DG+MVARGDLG+E P E++ L QK +I   N 
Sbjct: 214 LGMPDLPIIAKIETLQALDNLESIIEEADGVMVARGDLGVEAPVEQIPLLQKRIIEIANT 273

Query: 385 VGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMA 564
           + KP I ATQMLESMV  P PTRAE +D+ANAILDG D VMLS ET+ G YP + V  MA
Sbjct: 274 MAKPAITATQMLESMVNNPFPTRAEATDIANAILDGTDAVMLSEETSIGKYPEQAVKVMA 333

Query: 565 NICKEAEAVI 594
           N+ KE E ++
Sbjct: 334 NVAKETEKIL 343


>UniRef50_A7D456 Cluster: Pyruvate kinase; n=2;
           Halobacteriaceae|Rep: Pyruvate kinase - Halorubrum
           lacusprofundi ATCC 49239
          Length = 613

 Score =  190 bits (462), Expect = 4e-47
 Identities = 96/190 (50%), Positives = 127/190 (66%), Gaps = 1/190 (0%)
 Frame = +1

Query: 22  NAGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGIL 201
           + G L SRKGVNLPG+ +D+  ++ +D+++L        D + ASF+RN   ++ I   L
Sbjct: 170 SGGKLSSRKGVNLPGVAIDVDLITAEDEAELDLAARTNADFVAASFVRNANDVYRIADAL 229

Query: 202 GEKG-KNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARC 378
            E+G  +I I++KIE    + NLD II  +DG+MVARGDLG+E P E V + QK +I +C
Sbjct: 230 EERGGDDIPIVAKIERAGAVENLDGIIDAADGVMVARGDLGVECPLEDVPVIQKRIIRKC 289

Query: 379 NRVGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHT 558
              G PVI AT+ML+SMV   RPTRAE SDVANA+LDG D VMLSGETA GD PV  V T
Sbjct: 290 VNAGVPVITATEMLDSMVSSRRPTRAEASDVANAVLDGTDAVMLSGETAIGDDPVNVVET 349

Query: 559 MANICKEAEA 588
           M  I ++ E+
Sbjct: 350 MDRIVRQVES 359


>UniRef50_Q8PYY4 Cluster: Pyruvate kinase; n=3;
           Methanosarcinaceae|Rep: Pyruvate kinase - Methanosarcina
           mazei (Methanosarcina frisia)
          Length = 477

 Score =  189 bits (461), Expect = 5e-47
 Identities = 96/186 (51%), Positives = 121/186 (65%)
 Frame = +1

Query: 28  GMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGE 207
           G L S KG+NLPG  + L AV+EKD   L F +E+ +D    SF+ N   + ++R     
Sbjct: 152 GELYSHKGLNLPGAKIFLDAVTEKDFRILEFALEEDIDTFSISFVENAEDIRKVRNFAAS 211

Query: 208 KGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRV 387
           +GK + I+SKIE  Q + N+ EI+ E+D +MVARGDLG+EIP ++V   QK +I R   +
Sbjct: 212 RGKQVNIVSKIERRQAVENIGEILDETDALMVARGDLGVEIPIQEVPSVQKELIQRAKLL 271

Query: 388 GKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMAN 567
           G PVI AT ML SM    RPTRAE +DVANAILDG D VMLS ETA G+YPVE V  MA 
Sbjct: 272 GVPVITATHMLASMTDNIRPTRAEATDVANAILDGTDAVMLSEETAVGNYPVEAVEMMAK 331

Query: 568 ICKEAE 585
           I K  E
Sbjct: 332 IAKTTE 337


>UniRef50_Q44473 Cluster: Pyruvate kinase; n=4; Proteobacteria|Rep:
           Pyruvate kinase - Agrobacterium vitis (Rhizobium vitis)
          Length = 482

 Score =  189 bits (460), Expect = 7e-47
 Identities = 95/188 (50%), Positives = 125/188 (66%)
 Frame = +1

Query: 22  NAGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGIL 201
           N G L +RKGVN+PG  +D+  ++ KD+ DL FG+E GVD +  SF++    + E R ++
Sbjct: 152 NGGALSNRKGVNVPGAVLDISPLTAKDREDLEFGLELGVDWVALSFVQRARDMIEARSLV 211

Query: 202 GEKGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCN 381
           G++     +I+KIE    + ++++I+  SD +MVARGDLG+EIPPE V   QK +I  C 
Sbjct: 212 GDRAG---LIAKIEKPSALDDIEDIVRLSDSVMVARGDLGVEIPPEDVPGKQKEIIRACR 268

Query: 382 RVGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTM 561
              KPVI ATQML+SMV  P PTRAE SDVA AI DGAD VMLS ETA G YPVE V  M
Sbjct: 269 LAAKPVIVATQMLDSMVSSPTPTRAEASDVAGAIYDGADAVMLSAETATGAYPVEAVEIM 328

Query: 562 ANICKEAE 585
             I ++ E
Sbjct: 329 NRIIEKTE 336


>UniRef50_Q1NTW3 Cluster: Pyruvate kinase; n=1; delta
           proteobacterium MLMS-1|Rep: Pyruvate kinase - delta
           proteobacterium MLMS-1
          Length = 493

 Score =  188 bits (459), Expect = 9e-47
 Identities = 87/191 (45%), Positives = 130/191 (68%)
 Frame = +1

Query: 13  QQDNAGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIR 192
           Q  + G+LGSR+ +N+ G   DLPA++E+D +D+ FG+EQ VD I  SF+R    +  ++
Sbjct: 157 QSLDEGVLGSRRHLNIRGKSADLPAITEQDWADIEFGMEQRVDFIALSFVRTAEPIQVVQ 216

Query: 193 GILGEKGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIA 372
             L  +G  +++++KIE+   +  LD IIA +DG+MVARGDLG E+P E+V L Q  ++A
Sbjct: 217 QHLAARGVTMEVMAKIESAASIAQLDAIIAAADGVMVARGDLGAELPYEEVPLLQDEIVA 276

Query: 373 RCNRVGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECV 552
           +C R GKPV+ AT MLESM+  P PTRAE++D+ +A+  G+D +MLSGETA G YP + +
Sbjct: 277 KCRRAGKPVVVATHMLESMIVNPTPTRAEVTDITHAVQQGSDAIMLSGETATGRYPYKAL 336

Query: 553 HTMANICKEAE 585
             M  + +  E
Sbjct: 337 EVMDAVARRIE 347


>UniRef50_Q2I6K6 Cluster: Pyruvate kinase; n=1; uncultured delta
           proteobacterium DeepAnt-32C6|Rep: Pyruvate kinase -
           uncultured delta proteobacterium DeepAnt-32C6
          Length = 466

 Score =  188 bits (457), Expect = 2e-46
 Identities = 96/187 (51%), Positives = 126/187 (67%), Gaps = 1/187 (0%)
 Frame = +1

Query: 28  GMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQ-GVDMIFASFIRNGAALHEIRGILG 204
           GML  RKG+N+PG  +  PA+++KDK DL F V+  GVD I  SF+R  A + E + +  
Sbjct: 148 GMLSERKGINVPGSALSTPALTDKDKRDLAFAVDTIGVDWIALSFVRTAADILEAKSL-- 205

Query: 205 EKGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNR 384
              KN  +I+K+E  + + NL  I   +DG MVARGDLG+E+ PEKV L QK +I   N 
Sbjct: 206 --AKNTPVIAKLEKPEAIANLCAIADVADGAMVARGDLGVELGPEKVPLVQKRIIEEVNT 263

Query: 385 VGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMA 564
            GK VI ATQML+SM++ PRPTRAE +D+ANA+LDG D +MLSGETA G YP++ V  M 
Sbjct: 264 RGKLVITATQMLDSMIRNPRPTRAEAADIANAVLDGTDALMLSGETAVGRYPIKAVKMMD 323

Query: 565 NICKEAE 585
            I +E E
Sbjct: 324 VIIREVE 330


>UniRef50_A6Q7D7 Cluster: Pyruvate kinase; n=19; cellular
           organisms|Rep: Pyruvate kinase - Sulfurovum sp. (strain
           NBC37-1)
          Length = 488

 Score =  188 bits (457), Expect = 2e-46
 Identities = 94/189 (49%), Positives = 126/189 (66%)
 Frame = +1

Query: 19  DNAGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGI 198
           +N GML SRKGVN P   + +  ++EKDK D+L+G++  VD +  SF+++   +   R +
Sbjct: 150 ENNGMLSSRKGVNFPNTHLGINVLTEKDKKDILWGIKHEVDFMAISFVQHQKDMTAAREV 209

Query: 199 LGEKGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARC 378
           +   G ++++++KIE    + N+D I+  SDGIMVARGDLGIEIP   V L QK +I R 
Sbjct: 210 ITSNGGSVQLLAKIEKFDAIENIDAILEASDGIMVARGDLGIEIPYYDVPLIQKMLIKRA 269

Query: 379 NRVGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHT 558
           N + KPVI ATQML SM  K   +RAEISDVANA+LDGAD VMLS E+A G YP+  V T
Sbjct: 270 NNMSKPVIVATQMLLSMTTKVTASRAEISDVANAVLDGADAVMLSEESAIGHYPIRAVET 329

Query: 559 MANICKEAE 585
           M    + AE
Sbjct: 330 MVQTIQSAE 338


>UniRef50_Q46078 Cluster: Pyruvate kinase; n=19; Actinobacteria
           (class)|Rep: Pyruvate kinase - Corynebacterium
           glutamicum (Brevibacterium flavum)
          Length = 475

 Score =  186 bits (454), Expect = 4e-46
 Identities = 92/186 (49%), Positives = 127/186 (68%)
 Frame = +1

Query: 28  GMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGE 207
           G + + KGV+LPG+ + +PA+SEKD  DL F ++ GVD I  SF+R+ A    +  I+ E
Sbjct: 149 GPVSNNKGVSLPGMDISVPALSEKDIRDLRFALKLGVDFIALSFVRSPADAELVHKIMDE 208

Query: 208 KGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRV 387
           +G+ + +I+K+E  + + +L+ I+   D +MVARGDLG+E+P E+V L QK  I      
Sbjct: 209 EGRRVPVIAKLEKPEAVTSLEPIVLAFDAVMVARGDLGVEVPLEEVPLVQKRAIQIAREN 268

Query: 388 GKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMAN 567
            KPVI ATQML+SM++  RPTRAE SDVANA+LDGAD VMLSGET+ G  P   V TM+ 
Sbjct: 269 AKPVIVATQMLDSMIENSRPTRAEASDVANAVLDGADAVMLSGETSVGKDPHNVVRTMSR 328

Query: 568 ICKEAE 585
           I + AE
Sbjct: 329 IVRFAE 334


>UniRef50_O06134 Cluster: Pyruvate kinase; n=29; Bacteria|Rep:
           Pyruvate kinase - Mycobacterium tuberculosis
          Length = 472

 Score =  186 bits (453), Expect = 5e-46
 Identities = 89/181 (49%), Positives = 123/181 (67%)
 Frame = +1

Query: 28  GMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGE 207
           G +   KG++LPG+ V  PA+SEKD  DL F +  GVDM+  SF+R+ A +  +  ++  
Sbjct: 149 GPVSDNKGISLPGMNVTAPALSEKDIEDLTFALNLGVDMVALSFVRSPADVELVHEVMDR 208

Query: 208 KGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRV 387
            G+ + +I+K+E  + + NL+ I+   D +MVARGDLG+E+P E+V L QK  I      
Sbjct: 209 IGRRVPVIAKLEKPEAIDNLEAIVLAFDAVMVARGDLGVELPLEEVPLVQKRAIQMAREN 268

Query: 388 GKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMAN 567
            KPVI ATQML+SM++  RPTRAE SDVANA+LDGAD +MLSGET+ G YP+  V TM+ 
Sbjct: 269 AKPVIVATQMLDSMIENSRPTRAEASDVANAVLDGADALMLSGETSVGKYPLAAVRTMSR 328

Query: 568 I 570
           I
Sbjct: 329 I 329


>UniRef50_Q1IJ65 Cluster: Pyruvate kinase; n=6; Bacteria|Rep:
           Pyruvate kinase - Acidobacteria bacterium (strain
           Ellin345)
          Length = 485

 Score =  185 bits (450), Expect = 1e-45
 Identities = 94/186 (50%), Positives = 120/186 (64%)
 Frame = +1

Query: 28  GMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGE 207
           G L SRKG+NLPGI + + A +E D+  L F +E GVD +  SF++N   +  +R     
Sbjct: 152 GELRSRKGLNLPGINLGISAFTEHDRDCLKFALENGVDAVSQSFVQNAHDIELVRTAAES 211

Query: 208 KGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRV 387
            G +  I +KIE  + + N DEI+  SDGIMVARGDLGIE+P E++ + QK +I+  N  
Sbjct: 212 LGHHPFIFAKIERAEAVQNYDEILRASDGIMVARGDLGIEVPMEEIAVIQKQLISGANAA 271

Query: 388 GKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMAN 567
           GKPVI ATQMLESM+    PTRAE +DVANAI DG DCVMLSGE A G +P E V  +  
Sbjct: 272 GKPVITATQMLESMITNRLPTRAECTDVANAIFDGTDCVMLSGECAVGQFPEEAVAMLGK 331

Query: 568 ICKEAE 585
           I    E
Sbjct: 332 IAAATE 337


>UniRef50_A4APL1 Cluster: Pyruvate kinase; n=15; Bacteroidetes|Rep:
           Pyruvate kinase - Flavobacteriales bacterium HTCC2170
          Length = 480

 Score =  184 bits (449), Expect = 1e-45
 Identities = 88/187 (47%), Positives = 130/187 (69%), Gaps = 1/187 (0%)
 Frame = +1

Query: 28  GMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGE 207
           G L S+KGVNLP   + LPA++EKD  D  F +   VD I  SF+R+   + +++ I+ E
Sbjct: 152 GPLKSKKGVNLPNTNISLPALTEKDVKDAKFAISLDVDWIALSFVRHSQDIIDLQNIIKE 211

Query: 208 KGKN-IKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNR 384
             ++ I II+KIE  + + N+D+I++  DG+MVARGDLG+E+P  +V L QK ++ R  +
Sbjct: 212 HAEHKIPIIAKIEKPEAVENIDKIVSYCDGLMVARGDLGVEVPAHEVPLIQKKLVLRAKK 271

Query: 385 VGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMA 564
              PVI ATQM+E+M+    PTRAE++DVAN+++DGAD VMLSGET+ G+YPV+ +  MA
Sbjct: 272 ARIPVIIATQMMETMITSLTPTRAEVNDVANSVMDGADAVMLSGETSVGNYPVQVIEKMA 331

Query: 565 NICKEAE 585
           +I +  E
Sbjct: 332 SILESVE 338


>UniRef50_P94685 Cluster: Pyruvate kinase; n=8; Chlamydiaceae|Rep:
           Pyruvate kinase - Chlamydia trachomatis
          Length = 485

 Score =  184 bits (448), Expect = 2e-45
 Identities = 102/208 (49%), Positives = 133/208 (63%), Gaps = 3/208 (1%)
 Frame = +1

Query: 22  NAGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGIL 201
           N+G + S K +++  I V LP ++EKD +DL FGVEQ +D+I ASF+R    +  +R +L
Sbjct: 147 NSGEIKSNKSLSIKDIDVALPFMTEKDIADLKFGVEQELDLIAASFVRCNEDIDSMRKVL 206

Query: 202 GEKGK-NIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARC 378
              G+ N+ II+KIENH G+ N  EI   +DGIM+ARGDLGIE+   +V   QK M    
Sbjct: 207 ESFGRPNMPIIAKIENHLGVQNFQEIARAADGIMIARGDLGIELSIVEVPGLQKFMARAS 266

Query: 379 NRVGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHT 558
              G+  I ATQMLESM++ P PTRAE+SDVANAI DG   VMLSGETA G +PV  V T
Sbjct: 267 RETGRFCITATQMLESMIRNPLPTRAEVSDVANAIYDGTSAVMLSGETALGAHPVHAVKT 326

Query: 559 MANICKEAEAVIWHRQLF--NDLVSEVK 636
           M +I +E E    +   F  ND  S +K
Sbjct: 327 MRSIIQETEKTFDYHAFFQLNDKNSALK 354


>UniRef50_A1BQT0 Cluster: Pyruvate kinase; n=2; Eukaryota|Rep:
           Pyruvate kinase - Monocercomonoides sp. PA203
          Length = 516

 Score =  184 bits (447), Expect = 3e-45
 Identities = 97/191 (50%), Positives = 124/191 (64%), Gaps = 2/191 (1%)
 Frame = +1

Query: 19  DNAGMLGSRKGVNLPGIPVD-LPAVSEKDKSDLLFGVEQ-GVDMIFASFIRNGAALHEIR 192
           +  G +   KG+NLP   +  LPA++EKD  D  F ++   VD    SF+R    + ++R
Sbjct: 179 EQGGDVKDHKGINLPATDLGPLPALTEKDIEDAKFVLDTLEVDFFALSFVRKPQDVLDLR 238

Query: 193 GILGEKGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIA 372
            ++  KGK ++II KIE  + + NLDEI+A SD  MVARGDL +E+   KV   QK +I 
Sbjct: 239 HLIEAKGKEMRIIVKIEKPEAIKNLDEILAVSDACMVARGDLAVEVGTAKVPCLQKHIIR 298

Query: 373 RCNRVGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECV 552
            C  +G PVI ATQMLESM   P PTRAE +DVANAI DG DCVMLSGETA G++PVE V
Sbjct: 299 HCLEMGLPVITATQMLESMTHNPTPTRAEATDVANAIYDGTDCVMLSGETAAGEFPVETV 358

Query: 553 HTMANICKEAE 585
           HTM +I  E E
Sbjct: 359 HTMQDIILETE 369


>UniRef50_Q8G5M1 Cluster: Pyruvate kinase; n=23;
           Actinobacteridae|Rep: Pyruvate kinase - Bifidobacterium
           longum
          Length = 509

 Score =  183 bits (446), Expect = 3e-45
 Identities = 92/182 (50%), Positives = 120/182 (65%)
 Frame = +1

Query: 25  AGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILG 204
           AG + S KG+NLPG+ V LPA++EKD++DL + +  G D+I  SF+R    +     I+ 
Sbjct: 181 AGPVSSHKGINLPGVAVSLPALTEKDEADLRWAIRTGADIIAMSFVRFATDIDRAHEIMD 240

Query: 205 EKGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNR 384
           E+G+ I II+KIE  Q + NL+EI+   DG+M ARGD+ +E P E+V LA K +I    +
Sbjct: 241 EEGRRIPIIAKIEKPQALENLEEIVKTFDGVMAARGDMAVECPLEEVPLATKRIIELARQ 300

Query: 385 VGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMA 564
             KPVI AT++L SMV  P PTRAE SD ANAILDG+D  M S ETA G YP   V TMA
Sbjct: 301 YAKPVIVATEVLGSMVNSPVPTRAEASDCANAILDGSDATMTSNETAVGKYPDVTVATMA 360

Query: 565 NI 570
            I
Sbjct: 361 RI 362


>UniRef50_A0QNT2 Cluster: Pyruvate kinase; n=1; Mycobacterium
           smegmatis str. MC2 155|Rep: Pyruvate kinase -
           Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155)
          Length = 477

 Score =  183 bits (445), Expect = 5e-45
 Identities = 91/189 (48%), Positives = 123/189 (65%)
 Frame = +1

Query: 22  NAGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGIL 201
           + G +   KG++LP IPV +P +S+KD  DL F +E G DMI  SF+R    +     I+
Sbjct: 148 DGGPVSDHKGISLPNIPVSVPPLSDKDIEDLKFALELGADMIAMSFVRAPEEVELAHKIM 207

Query: 202 GEKGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCN 381
            E G+ + +I+K+E  + + +L  I+   DG+MVARGDLG+E+P E++ L Q+  IA C 
Sbjct: 208 DEVGRRVPVIAKLEKPEAVSDLPAIVEAFDGLMVARGDLGVEMPLEQIPLVQRRAIALCR 267

Query: 382 RVGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTM 561
           +  KPVI ATQML+SMV   RPTRAE+SDVANA+ D AD VMLS ET+ G  P   V TM
Sbjct: 268 QAAKPVIVATQMLDSMVSDRRPTRAEVSDVANAVFDRADAVMLSAETSVGADPAHAVATM 327

Query: 562 ANICKEAEA 588
           A I   AE+
Sbjct: 328 ARIVVAAES 336


>UniRef50_Q81N35 Cluster: Pyruvate kinase; n=11; Bacillus cereus
           group|Rep: Pyruvate kinase - Bacillus anthracis
          Length = 352

 Score =  182 bits (444), Expect = 6e-45
 Identities = 93/189 (49%), Positives = 127/189 (67%), Gaps = 1/189 (0%)
 Frame = +1

Query: 28  GMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGE 207
           G + S KGVNLPG  V LPA++EKDK D+ F +E+ VD I  SF+R  + + EIR  + +
Sbjct: 143 GNISSHKGVNLPGAIVSLPAITEKDKKDIQFLLEEDVDFIACSFVRKPSHIKEIRDFIQQ 202

Query: 208 -KGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNR 384
            K  +  +I+KIE  + + N  +I  E+DGIM+ARGDLG+E+P + + L QK MI  CNR
Sbjct: 203 YKETSPNLIAKIETMEAIENFQDICKEADGIMIARGDLGVELPYQFIPLLQKMMIQECNR 262

Query: 385 VGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMA 564
               VI ATQML+SMV    PTRAE++DV  A+LDG + VMLS E+A G++PVE V T+ 
Sbjct: 263 TNTYVITATQMLQSMVDHSIPTRAEVTDVFQAVLDGTNAVMLSAESASGEHPVESVSTLR 322

Query: 565 NICKEAEAV 591
            + + AE V
Sbjct: 323 LVSEFAEHV 331


>UniRef50_A0L7K0 Cluster: Pyruvate kinase; n=1; Magnetococcus sp.
           MC-1|Rep: Pyruvate kinase - Magnetococcus sp. (strain
           MC-1)
          Length = 569

 Score =  181 bits (441), Expect = 1e-44
 Identities = 89/189 (47%), Positives = 124/189 (65%)
 Frame = +1

Query: 19  DNAGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGI 198
           ++ G+L S KG+N+P   +  P+++ KD+ DL FGV+  VD +  SF+R+   +  ++ +
Sbjct: 149 EHGGLLKSHKGINMPDASISAPSLTTKDQQDLFFGVKHDVDYVALSFVRSAKCVQNVKFM 208

Query: 199 LGEKGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARC 378
           L  +     II+KIE  + + N+DEII   DGIM+ARGD+ +EI   +V   Q+ +I +C
Sbjct: 209 LHRRKIYKPIIAKIERPEAIRNIDEIIKVVDGIMIARGDMAVEIGNHRVPSVQRQIIQKC 268

Query: 379 NRVGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHT 558
              GKPVI ATQMLESM++ P PTRAE SDVANAI DG D VMLS ET+ G  P+  V T
Sbjct: 269 RAKGKPVITATQMLESMIQNPSPTRAEASDVANAIWDGTDAVMLSAETSVGVDPINTVLT 328

Query: 559 MANICKEAE 585
           M  I +EAE
Sbjct: 329 MGRIVEEAE 337


>UniRef50_O05118 Cluster: Pyruvate kinase; n=44; Proteobacteria|Rep:
           Pyruvate kinase - Methylobacterium extorquens
           (Protomonas extorquens)
          Length = 483

 Score =  181 bits (440), Expect = 2e-44
 Identities = 93/192 (48%), Positives = 130/192 (67%), Gaps = 2/192 (1%)
 Frame = +1

Query: 28  GMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGE 207
           G + +RKGV+LP   + +PA++EKD+ DL  G+  G D I  SF++    + E++ +   
Sbjct: 156 GRISNRKGVSLPHTALPVPAMTEKDRGDLEAGLAAGADWIAVSFVQRPEDVAEVKKVAA- 214

Query: 208 KGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRV 387
            G+ + +++KIE  Q +  LDEII  SDGIMVARGDLG+E+P E+V   QK +     R+
Sbjct: 215 -GRAL-VMAKIEKPQALTRLDEIIEISDGIMVARGDLGVEMPLEQVPGVQKRITRVARRL 272

Query: 388 GKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMAN 567
           GKPV+ ATQMLESM+  P PTRAE+SDVA A+ +GAD VMLS E+A GD+PVE + TM  
Sbjct: 273 GKPVVVATQMLESMITSPVPTRAEVSDVATAVYEGADAVMLSAESAAGDFPVEAIGTMNR 332

Query: 568 ICKEAE--AVIW 597
           I ++ E  A+ W
Sbjct: 333 IAEQVERDALYW 344


>UniRef50_Q57572 Cluster: Pyruvate kinase; n=6; Methanococcales|Rep:
           Pyruvate kinase - Methanococcus jannaschii
          Length = 447

 Score =  179 bits (435), Expect = 7e-44
 Identities = 87/199 (43%), Positives = 126/199 (63%)
 Frame = +1

Query: 28  GMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGE 207
           G +    GVNLP   ++LP + E D  ++ F VE+  + I  SF+RN   + E++ I+ E
Sbjct: 132 GEIKEGMGVNLPDTRIELPIIDETDLKNIKFAVEKDFEYIALSFVRNKEDVKELKDIISE 191

Query: 208 KGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRV 387
              + ++ISKIE  +G+ N+ EI  ESDG+MVARGDLG+E+P E + + QK ++   NR 
Sbjct: 192 YKGDCEVISKIETKEGLKNIKEIARESDGVMVARGDLGVEVPIENIPIEQKNILRIANRY 251

Query: 388 GKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMAN 567
           G   I ATQ+L+SM+  P PTRAE++D+ANAI DG DC+MLS ET  G YP+E +  +  
Sbjct: 252 GILSITATQILDSMINNPFPTRAEVTDIANAIYDGTDCLMLSNETTIGKYPIEAIKVLNK 311

Query: 568 ICKEAEAVIWHRQLFNDLV 624
           + K A+    H + F D V
Sbjct: 312 VAKVADE---HYEEFGDRV 327


>UniRef50_Q7P1G4 Cluster: Pyruvate kinase; n=4; Bacteria|Rep:
           Pyruvate kinase - Chromobacterium violaceum
          Length = 468

 Score =  178 bits (434), Expect = 1e-43
 Identities = 87/186 (46%), Positives = 121/186 (65%)
 Frame = +1

Query: 28  GMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGE 207
           G L S KG NLP   + L A++ KD+ D  F +E+G D +  SF++  A +  +R I+G 
Sbjct: 148 GELSSNKGFNLPHTVLPLSAITGKDRKDAEFALEEGADWVAMSFVQTAADVKALRDIVG- 206

Query: 208 KGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRV 387
             K + I++KIE    + +L+ I   +DG+MVARGDLG+E+PPE V + Q+ ++  C  +
Sbjct: 207 --KRVGIVAKIEKPSAVDDLEAIAELADGVMVARGDLGVELPPEDVPVVQRRIVHHCRHL 264

Query: 388 GKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMAN 567
           G+PVI ATQMLESM+  P PTRAE +DVA A+ +GAD VMLS ETA G YP+E V  M  
Sbjct: 265 GRPVIVATQMLESMITAPTPTRAEANDVATAVYEGADAVMLSAETAAGQYPLEAVQIMDR 324

Query: 568 ICKEAE 585
           I +  E
Sbjct: 325 IIRRVE 330


>UniRef50_A1IEN3 Cluster: Pyruvate kinase; n=1; Candidatus
           Desulfococcus oleovorans Hxd3|Rep: Pyruvate kinase -
           Candidatus Desulfococcus oleovorans Hxd3
          Length = 478

 Score =  177 bits (431), Expect = 2e-43
 Identities = 84/191 (43%), Positives = 126/191 (65%)
 Frame = +1

Query: 13  QQDNAGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIR 192
           +  N+G++ S KG++ PG+ +DLPA++ KD+SD+   ++ G+D +  SF++    + +++
Sbjct: 149 ETQNSGLVSSNKGISFPGLAIDLPALTAKDRSDVAAALDVGIDALALSFVQKSQDVVDLK 208

Query: 193 GILGEKGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIA 372
             +   G+ + +I KIE    + +  EI+AE+D IMVARGDLG+E     + + QK +I 
Sbjct: 209 KEMEHHGRQVPVIVKIERMNAIDHFQEIVAEADVIMVARGDLGLECSLPALPVIQKRIID 268

Query: 373 RCNRVGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECV 552
            C    KPV+ ATQML SMV  P PTRAE++DVANAI+DGAD VMLS ETA G+YPVE  
Sbjct: 269 MCAEHQKPVVVATQMLLSMVHNPLPTRAEVADVANAIMDGADAVMLSEETAVGEYPVEAA 328

Query: 553 HTMANICKEAE 585
             +A + +  E
Sbjct: 329 GMLAQVAEHTE 339


>UniRef50_A7CAK5 Cluster: Pyruvate kinase; n=3; Ralstonia
           pickettii|Rep: Pyruvate kinase - Ralstonia pickettii 12D
          Length = 507

 Score =  177 bits (430), Expect = 3e-43
 Identities = 92/208 (44%), Positives = 133/208 (63%)
 Frame = +1

Query: 22  NAGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGIL 201
           + G L  RKGVN+P   + +PA++EKD  DL F +  GVD I  SF++    +   R I+
Sbjct: 164 DGGPLSDRKGVNVPDAVIPIPALTEKDLRDLDFALSLGVDWIALSFVQRAEDVIAAREII 223

Query: 202 GEKGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCN 381
           G++     ++SKIE    +++L++I+  SD +MVARGDLG+E+PPE+V   QK ++    
Sbjct: 224 GDRAG---LLSKIEKPAALLHLEDIVQASDALMVARGDLGVELPPERVPGVQKRILRMAR 280

Query: 382 RVGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTM 561
           + GKPV+ ATQMLESM++ P PTRAE SDVA+A+ DG D VMLS E+A G +PV  V  M
Sbjct: 281 QHGKPVVVATQMLESMIEAPVPTRAEASDVASAVYDGTDAVMLSAESASGKHPVAAVSIM 340

Query: 562 ANICKEAEAVIWHRQLFNDLVSEVKPPI 645
             I  E E    +R L +   ++ +PP+
Sbjct: 341 NRIIAETERDPLYRNLID---AQHQPPL 365


>UniRef50_Q56XD5 Cluster: Pyruvate kinase; n=14; Magnoliophyta|Rep:
           Pyruvate kinase - Arabidopsis thaliana (Mouse-ear cress)
          Length = 579

 Score =  176 bits (429), Expect = 4e-43
 Identities = 88/191 (46%), Positives = 121/191 (63%)
 Frame = +1

Query: 22  NAGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGIL 201
           + G L SR+ +N+ G    LP+++EKD  D+ FGVE  VD    SF+++   +HE++  L
Sbjct: 254 DGGELKSRRHLNVRGKSATLPSITEKDWEDIKFGVENKVDFYAVSFVKDAQVVHELKKYL 313

Query: 202 GEKGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCN 381
              G +I +I KIE+   + NL  II  SDG MVARGDLG E+P E+V + Q+ +I  C 
Sbjct: 314 QNSGADIHVIVKIESADSIPNLHSIITASDGAMVARGDLGAELPIEEVPILQEEIINLCR 373

Query: 382 RVGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTM 561
            +GK VI A  MLESM+  P PTRAE+SD+A A+ +GAD VMLSGETA G +P++    M
Sbjct: 374 SMGKAVIVAANMLESMIVHPTPTRAEVSDIAIAVREGADAVMLSGETAHGKFPLKAAGVM 433

Query: 562 ANICKEAEAVI 594
             +    EA I
Sbjct: 434 HTVALRTEATI 444


>UniRef50_Q40546 Cluster: Pyruvate kinase isozyme G, chloroplast
           precursor; n=58; Viridiplantae|Rep: Pyruvate kinase
           isozyme G, chloroplast precursor - Nicotiana tabacum
           (Common tobacco)
          Length = 562

 Score =  176 bits (429), Expect = 4e-43
 Identities = 88/189 (46%), Positives = 122/189 (64%)
 Frame = +1

Query: 22  NAGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGIL 201
           + G L SR+ +N+ G    LP+++EKD  D+ FGV   VD    SF+++   +HE++  L
Sbjct: 235 DGGELKSRRHLNVRGKSATLPSITEKDWDDIKFGVNNQVDFYAVSFVKDAKVVHELKDYL 294

Query: 202 GEKGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCN 381
                +I +I KIE+   + NL  II+ SDG MVARGDLG E+P E+V L Q+ +I RC 
Sbjct: 295 KSCNADIHVIVKIESADSIPNLHSIISASDGAMVARGDLGAELPIEEVPLLQEDIIRRCQ 354

Query: 382 RVGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTM 561
            + KPVI AT MLESM+  P PTRAE+SD++ A+ +GAD VMLSGETA G YP++ V  M
Sbjct: 355 SMQKPVIVATNMLESMIDHPTPTRAEVSDISIAVREGADAVMLSGETAHGKYPLKAVKVM 414

Query: 562 ANICKEAEA 588
             +    E+
Sbjct: 415 HIVALRTES 423


>UniRef50_UPI00015BD1E0 Cluster: UPI00015BD1E0 related cluster; n=1;
           unknown|Rep: UPI00015BD1E0 UniRef100 entry - unknown
          Length = 477

 Score =  176 bits (428), Expect = 5e-43
 Identities = 93/190 (48%), Positives = 126/190 (66%), Gaps = 2/190 (1%)
 Frame = +1

Query: 22  NAGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGIL 201
           +AG + S KGVNLP + + + A+ + +K  + F  +  +D I  SF+++   + + +   
Sbjct: 146 SAGKISSHKGVNLPNVDLPVRAIGDYEKRCIDFAKKIDMDAISVSFVKDQRDVIDAKEYC 205

Query: 202 GEKGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCN 381
                +  II+KIE  Q + N+DEI+  SDGIMVARGDLGIE P E + +AQK +I + N
Sbjct: 206 NTIDYHPFIIAKIERPQALKNIDEILEASDGIMVARGDLGIETPIECIAMAQKHIIKKAN 265

Query: 382 RVGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTM 561
             GKPVI ATQMLESM++ PRPTRAE SDVANAILDG DC+M+S E+A G +P   V T+
Sbjct: 266 LAGKPVITATQMLESMIESPRPTRAEASDVANAILDGTDCIMVSEESAIGKHPDLVVSTL 325

Query: 562 ANI--CKEAE 585
           ANI  C E E
Sbjct: 326 ANIAACVEKE 335


>UniRef50_Q63P20 Cluster: Pyruvate kinase; n=74; Proteobacteria|Rep:
           Pyruvate kinase - Burkholderia pseudomallei (Pseudomonas
           pseudomallei)
          Length = 484

 Score =  176 bits (428), Expect = 5e-43
 Identities = 93/204 (45%), Positives = 124/204 (60%)
 Frame = +1

Query: 28  GMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGE 207
           G++  RKGV++P   + +PA+S KD+ DL FG+  GVD +  SF++    + + R ++G 
Sbjct: 159 GIVSDRKGVSVPDATLAIPALSAKDRDDLEFGLSLGVDWVALSFVQTAQDVRDARALIGA 218

Query: 208 KGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRV 387
           +     I++KIE  Q + N+ EI+  +D +MVARGDLG+E+  E V   QK +I      
Sbjct: 219 RAA---IVAKIEKPQAVANIAEIVDAADAVMVARGDLGVEMSLEDVPSVQKQIIRLARAA 275

Query: 388 GKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMAN 567
           GKPVI ATQMLESM   P PTRAE SDVA A+ DGAD VMLS E+A G YPVE V  M  
Sbjct: 276 GKPVIVATQMLESMTLAPTPTRAEASDVAAAVYDGADAVMLSAESASGQYPVEAVDFMRK 335

Query: 568 ICKEAEAVIWHRQLFNDLVSEVKP 639
           I    EA     QL   +V+   P
Sbjct: 336 IISTTEADPIQPQLMKAIVTAHAP 359


>UniRef50_Q9PF54 Cluster: Pyruvate kinase; n=11;
           Xanthomonadaceae|Rep: Pyruvate kinase - Xylella
           fastidiosa
          Length = 501

 Score =  175 bits (427), Expect = 7e-43
 Identities = 93/188 (49%), Positives = 121/188 (64%)
 Frame = +1

Query: 22  NAGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGIL 201
           N G+L  RKG+N  G  + L A++++D+  +      GVD I  SF R+   +HE R I 
Sbjct: 165 NDGVLSDRKGLNKQGGGLSLGALTDRDRELIGIVSRMGVDFIAVSFCRHAEEMHEARRIA 224

Query: 202 GEKGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCN 381
            E G +  ++SKIE  + +VNL EI+A SD +MVARGDLG+EI   ++   QK +I    
Sbjct: 225 RECGCDAALVSKIERAEAIVNLAEIVAASDVVMVARGDLGVEIGDAQLPGLQKKIIKEAL 284

Query: 382 RVGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTM 561
              K VI ATQML+SMV+ P PTRAE+ DVANA++DG D VMLS ETA GDYPV+ V  M
Sbjct: 285 LQNKVVITATQMLQSMVESPMPTRAEVLDVANAVIDGTDAVMLSAETATGDYPVKAVEAM 344

Query: 562 ANICKEAE 585
           A IC  AE
Sbjct: 345 ARICLGAE 352


>UniRef50_Q8TJ98 Cluster: Pyruvate kinase; n=2; Methanomicrobia|Rep:
           Pyruvate kinase - Methanosarcina acetivorans
          Length = 489

 Score =  175 bits (427), Expect = 7e-43
 Identities = 90/186 (48%), Positives = 117/186 (62%)
 Frame = +1

Query: 28  GMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGE 207
           G L S KG+NLPG  + L +V+E D   L F + + VD +  SF+     + ++R     
Sbjct: 164 GQLYSHKGLNLPGAKIYLDSVTEHDFKILEFALNEEVDAVSISFVEKAEDIRKVRNFAST 223

Query: 208 KGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRV 387
            GK + ++SKIE  Q + N++EI+ E+D +MVARGDLG+EIP ++V   QK +I     +
Sbjct: 224 MGKPVYVVSKIERSQAVQNIEEILEETDALMVARGDLGVEIPIQEVPSVQKELIRSAKLL 283

Query: 388 GKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMAN 567
             PVI AT ML SM    RPTRAE +DVANAILDG D VMLS ETA G+YPVE V  MA 
Sbjct: 284 SIPVITATHMLASMTDNIRPTRAEATDVANAILDGTDAVMLSEETAVGNYPVETVEMMAK 343

Query: 568 ICKEAE 585
           I K  E
Sbjct: 344 IAKTTE 349


>UniRef50_A0L5K6 Cluster: Pyruvate kinase; n=5; Proteobacteria|Rep:
           Pyruvate kinase - Magnetococcus sp. (strain MC-1)
          Length = 483

 Score =  175 bits (426), Expect = 9e-43
 Identities = 91/187 (48%), Positives = 119/187 (63%)
 Frame = +1

Query: 28  GMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGE 207
           G+L  RKG+N+P   + + A+++KD  DL FG+E G+D    SF++    L E R ++  
Sbjct: 151 GILSDRKGLNVPAAMLPVKALTDKDLEDLEFGLELGIDWCALSFVQRPEDLREARKLIHG 210

Query: 208 KGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRV 387
           +     +++KIE  Q + NL+EI+  +DG+MVARGDLG+E  PE+V   QK +I  C   
Sbjct: 211 RAA---LLAKIEKPQAVDNLEEIVKVADGVMVARGDLGVEYTPERVPAVQKRLIRMCREQ 267

Query: 388 GKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMAN 567
            KPVI ATQMLESM+  P PTRAE SDVANAI DGAD VMLS ETA G Y    V  M  
Sbjct: 268 CKPVIVATQMLESMIDAPIPTRAEASDVANAIYDGADAVMLSAETAVGSYACNAVSVMDR 327

Query: 568 ICKEAEA 588
           I +  EA
Sbjct: 328 IARVTEA 334


>UniRef50_A3ZTM3 Cluster: Pyruvate kinase; n=1; Blastopirellula
           marina DSM 3645|Rep: Pyruvate kinase - Blastopirellula
           marina DSM 3645
          Length = 490

 Score =  175 bits (425), Expect = 1e-42
 Identities = 82/189 (43%), Positives = 123/189 (65%)
 Frame = +1

Query: 28  GMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGE 207
           G+L SR+G+NLPG  + +  ++ +D+  + +  E  +D +  SF+R    + +++ +L  
Sbjct: 157 GILRSRQGINLPGTKLGVETITPRDRDHIRWAAETDLDYVSLSFVREADDIRQLKDLLQA 216

Query: 208 KGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRV 387
                 +I+KIE  + + NL+EI+  S+G+MVARGDLG+EI   +V  AQK ++  C R+
Sbjct: 217 HESRAMVIAKIEKREALDNLEEIVEVSNGVMVARGDLGVEIDVAEVAAAQKLIVKTCTRI 276

Query: 388 GKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMAN 567
           G+PVI ATQML+SM K  RPTRAE +DVANAILDGAD  MLS ETA G++P+  +  M  
Sbjct: 277 GRPVIVATQMLDSMTKNSRPTRAEATDVANAILDGADACMLSQETAVGEHPIVVIKMMNR 336

Query: 568 ICKEAEAVI 594
           I    E ++
Sbjct: 337 IMLATEKML 345


>UniRef50_Q8EWX2 Cluster: Pyruvate kinase; n=1; Mycoplasma
           penetrans|Rep: Pyruvate kinase - Mycoplasma penetrans
          Length = 498

 Score =  173 bits (422), Expect = 3e-42
 Identities = 91/189 (48%), Positives = 123/189 (65%), Gaps = 1/189 (0%)
 Frame = +1

Query: 22  NAGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGIL 201
           N  +L   K +NLP     +P +S+KD++D++F ++   D I ASF+  G  + EI+ IL
Sbjct: 176 NTWILRENKRINLPDSNYSIPFMSDKDRNDIIFAIKNKFDYIAASFVNTGDNVREIKKIL 235

Query: 202 GEKG-KNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARC 378
            E G ++I+IISKIE   G+ +LD+II ESD IMVARGDLG+E+P   V   +K +I  C
Sbjct: 236 KEHGGEHIQIISKIETMTGIKSLDDIIDESDSIMVARGDLGLEVPYYDVPTYEKYIIKDC 295

Query: 379 NRVGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHT 558
              GK VI ATQML+S+  K +PTRAE++DV  A+  G DC MLSGETA G YP+  V  
Sbjct: 296 RHKGKTVIVATQMLDSLETKIQPTRAEVTDVFFAVERGTDCTMLSGETANGMYPINAVEV 355

Query: 559 MANICKEAE 585
           MA I   +E
Sbjct: 356 MAKIDVSSE 364


>UniRef50_Q94KE3 Cluster: Pyruvate kinase; n=25; Magnoliophyta|Rep:
           Pyruvate kinase - Arabidopsis thaliana (Mouse-ear cress)
          Length = 527

 Score =  173 bits (420), Expect = 5e-42
 Identities = 91/233 (39%), Positives = 139/233 (59%), Gaps = 3/233 (1%)
 Frame = +1

Query: 25  AGMLGSRKGVNLPGIPVDLPAVSEKDKSDL-LFGVEQGVDMIFASFIRNGAALHEIRGIL 201
           A + GS   ++   + +DLP ++EKDK  +  +GV+  +D +  S+ R+   + + R +L
Sbjct: 183 ATLAGSLFTLHSSQVHIDLPTLTEKDKEVISTWGVQNKIDFLSLSYCRHAEDVRQTREML 242

Query: 202 GEKG--KNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIAR 375
            + G     +I +KIEN +G+ + DEI+ E+DGI+++RG+LGI++PPEKVFL QK  + +
Sbjct: 243 KKLGDLSQTQIFAKIENVEGLTHFDEILQEADGIILSRGNLGIDLPPEKVFLFQKAALYK 302

Query: 376 CNRVGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVH 555
           CN  GKP +  T++++SM    RPTRAE +DVANA+LDG+D ++L  ET +G YPVE + 
Sbjct: 303 CNMAGKPAV-LTRVVDSMTDNLRPTRAEATDVANAVLDGSDAILLGAETLRGLYPVETIS 361

Query: 556 TMANICKEAEAVIWHRQLFNDLVSEVKPPIDPXXXXXXXXXXXXTKCLASAIV 714
           T+  IC EAE V      F   V  V  P+               K  AS I+
Sbjct: 362 TVGRICAEAEKVFNQDLYFKKTVKYVGEPMTHLESIASSAVRAAIKVKASVII 414


>UniRef50_A5C814 Cluster: Pyruvate kinase; n=1; Vitis vinifera|Rep:
           Pyruvate kinase - Vitis vinifera (Grape)
          Length = 621

 Score =  171 bits (415), Expect = 2e-41
 Identities = 84/171 (49%), Positives = 117/171 (68%)
 Frame = +1

Query: 22  NAGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGIL 201
           + G L SR+ +N+ G    LP++++KD  D+ FGV+  VD    SF+++   +HE++  L
Sbjct: 310 DGGELKSRRHLNVRGKSATLPSITDKDWEDIKFGVDNQVDFYAVSFVKDAEVVHELKDYL 369

Query: 202 GEKGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCN 381
              G +I +I KIE+   + NL  II+ SDG MVARGDLG E+P E+V L Q+ +I RC+
Sbjct: 370 RSCGADIHVIVKIESADSIPNLHSIISASDGAMVARGDLGAELPIEEVPLLQEDIIRRCH 429

Query: 382 RVGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGD 534
            + KPVI AT MLESM+  P PTRAE+SD+A A+ +GAD VMLSGETA G+
Sbjct: 430 SMQKPVIVATNMLESMINHPTPTRAEVSDIAIAVREGADAVMLSGETAHGN 480


>UniRef50_Q9WY51 Cluster: Pyruvate kinase; n=3; Thermotogaceae|Rep:
           Pyruvate kinase - Thermotoga maritima
          Length = 466

 Score =  169 bits (411), Expect = 6e-41
 Identities = 81/186 (43%), Positives = 123/186 (66%)
 Frame = +1

Query: 28  GMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGE 207
           G +  R+GVN+P   + + +++++D+  +  G    V+    SF+R    + + +  + +
Sbjct: 148 GKITHRRGVNVPTADLSVESITDRDREFIKLGTLHDVEFFALSFVRKPEDVLKAKEEIRK 207

Query: 208 KGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRV 387
            GK I +ISKIE  + +  L+EII  SDGIMVARGDLG+EIP E+V + QK +I      
Sbjct: 208 HGKEIPVISKIETKKALERLEEIIKVSDGIMVARGDLGVEIPIEEVPIVQKEIIKLSKYY 267

Query: 388 GKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMAN 567
            KPVI ATQ+LESM++ P PTRAE++D+ANAI DGAD ++L+ ETA G +P+E +  ++ 
Sbjct: 268 SKPVIVATQILESMIENPFPTRAEVTDIANAIFDGADALLLTAETAVGKHPLEAIKVLSK 327

Query: 568 ICKEAE 585
           + KEAE
Sbjct: 328 VAKEAE 333


>UniRef50_A6C474 Cluster: Pyruvate kinase; n=1; Planctomyces maris
           DSM 8797|Rep: Pyruvate kinase - Planctomyces maris DSM
           8797
          Length = 489

 Score =  168 bits (408), Expect = 1e-40
 Identities = 84/194 (43%), Positives = 129/194 (66%), Gaps = 2/194 (1%)
 Frame = +1

Query: 19  DNAGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGI 198
           +  G++ S++GVNLPG+ +  P ++EKD SDL + VE G+D I  SF+R+   + +++  
Sbjct: 158 EREGIIRSKQGVNLPGVQLSTPCLTEKDLSDLAWAVEHGLDYIGLSFVRSADDIRQLKEE 217

Query: 199 LGEKGKNIK--IISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIA 372
           + +        +++KIE  + + ++++I+  +D +MVARGDLG+E+  E+V + QK +I 
Sbjct: 218 IEKLNPEDAPHVVAKIEKIEAVSDIEQILKLTDAVMVARGDLGVEVDIERVPIIQKRIIH 277

Query: 373 RCNRVGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECV 552
            CN+   PVI ATQML+SM     PTRAE SDVANA+LDG+D VMLSGETA G  P+  V
Sbjct: 278 LCNQYRVPVITATQMLDSMQFNTFPTRAEASDVANAVLDGSDAVMLSGETAVGVSPLAAV 337

Query: 553 HTMANICKEAEAVI 594
             M+ I +EA  ++
Sbjct: 338 EMMSRIVREAARIL 351


>UniRef50_A5JEK8 Cluster: Pyruvate kinase; n=1; Nosema bombycis|Rep:
           Pyruvate kinase - Nosema bombycis
          Length = 441

 Score =  168 bits (408), Expect = 1e-40
 Identities = 83/189 (43%), Positives = 123/189 (65%)
 Frame = +1

Query: 22  NAGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGIL 201
           N+  L + K  +LPG+  +      +DK D    ++  +D++FASFI +   +  ++ ++
Sbjct: 144 NSHRLKNNKKASLPGLVFEDNESEARDKKDFEIILKHKIDVVFASFINSRKEVESLKKLI 203

Query: 202 GEKGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCN 381
           G +  ++ I SKIE  +G+ N+DEII  SDGIM+ARGDLG+E+   K+F  QK +  +C 
Sbjct: 204 GSE--DVLIFSKIETLRGVENIDEIIEVSDGIMIARGDLGVEMTASKMFSTQKKITIKCR 261

Query: 382 RVGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTM 561
              KPVICATQMLE+M++ P P+RAEI+DV NA+ D  D ++LSGETA G +P   V TM
Sbjct: 262 EAKKPVICATQMLETMIQNPVPSRAEITDVGNAVFDQFDGLLLSGETAVGKFPTLTVRTM 321

Query: 562 ANICKEAEA 588
             I ++AEA
Sbjct: 322 RKIIEDAEA 330


>UniRef50_P32044 Cluster: Pyruvate kinase; n=2; Thermoplasma|Rep:
           Pyruvate kinase - Thermoplasma acidophilum
          Length = 544

 Score =  168 bits (408), Expect = 1e-40
 Identities = 84/188 (44%), Positives = 121/188 (64%)
 Frame = +1

Query: 22  NAGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGIL 201
           N G+L  R  VN+PG  ++L  ++++D++ +  G+  GVD    SF++    +  +R  +
Sbjct: 131 NDGVLRDRSRVNIPGRFIELGTITDRDRAFIREGIADGVDFFALSFVQKSENVDSLRDFV 190

Query: 202 GEKGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCN 381
            + G +  IISKIE   G+ N++EI+  SDGIMVARGDLG+E+P ++V LAQK +I   +
Sbjct: 191 IDSGGDQYIISKIETKSGLDNIEEIVKSSDGIMVARGDLGVELPLKEVVLAQKHIIKTAH 250

Query: 382 RVGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTM 561
             G   I ATQ+LESMV    PTRAEISD+ NAI+D AD +MLS E+A G YPV+ V T+
Sbjct: 251 EDGDFTIVATQVLESMVNNSSPTRAEISDITNAIIDNADALMLSEESAIGKYPVQAVRTL 310

Query: 562 ANICKEAE 585
             +    E
Sbjct: 311 KEVSDYVE 318


>UniRef50_Q1ZJ78 Cluster: Pyruvate kinase; n=1; Psychromonas sp.
           CNPT3|Rep: Pyruvate kinase - Psychromonas sp. CNPT3
          Length = 485

 Score =  165 bits (401), Expect = 1e-39
 Identities = 87/199 (43%), Positives = 124/199 (62%), Gaps = 5/199 (2%)
 Frame = +1

Query: 22  NAGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGIL 201
           N+G L +RKG+NL G  +  PA++ KD  D+        D +  SF RN   +H  R   
Sbjct: 150 NSGKLSNRKGINLLGGGLSAPALTPKDIEDMSTAALLNADFLAISFPRNAQDIHYARKKA 209

Query: 202 GEKGKNIKIISKIENHQGMVN---LDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIA 372
            E G +++II+K+E  + + +   +DE+I  +D IMVARGDLG+EI   ++   QK +I+
Sbjct: 210 KEAGCDVQIIAKVERAEVVASEKAMDEMIQAADIIMVARGDLGVEIGDARLARIQKQLIS 269

Query: 373 RCNRVGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECV 552
           R     KPVI ATQM+ESM++ P PTRAE+ D+ANA++DG+D +MLS E+A G YPVE V
Sbjct: 270 RSKYFAKPVITATQMMESMIENPMPTRAEVLDIANAVMDGSDAIMLSAESAAGRYPVEAV 329

Query: 553 HTMANICKEAEA--VIWHR 603
             M  I   AE   V+ H+
Sbjct: 330 QAMVRIAAGAEEPNVVMHK 348


>UniRef50_Q8ZNW0 Cluster: Pyruvate kinase II; n=173;
           Proteobacteria|Rep: Pyruvate kinase II - Salmonella
           typhimurium
          Length = 480

 Score =  164 bits (399), Expect = 2e-39
 Identities = 87/198 (43%), Positives = 122/198 (61%), Gaps = 3/198 (1%)
 Frame = +1

Query: 7   FEQQDNAGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHE 186
           F +    G L + KG+N  G  +   A++EKDK+D+      GVD +  SF R G  L+ 
Sbjct: 147 FTEVTVGGPLSNNKGINKLGGGLSAEALTEKDKADIQTAALIGVDYLAVSFPRCGEDLNY 206

Query: 187 IRGILGEKGKNIKIISKIENHQGMVN---LDEIIAESDGIMVARGDLGIEIPPEKVFLAQ 357
            R +  + G + KI++K+E  + + +   +D+II  SD +MVARGDLG+EI   ++   Q
Sbjct: 207 ARRLARDAGCDAKIVAKVERAEAVCDQNAMDDIILASDVVMVARGDLGVEIGDPELVGIQ 266

Query: 358 KTMIARCNRVGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDY 537
           K +I R  ++ + VI ATQM+ESM+  P PTRAE+ DVANA+LDG D VMLS ETA G Y
Sbjct: 267 KALIRRARQLNRAVITATQMMESMITNPMPTRAEVMDVANAVLDGTDAVMLSAETAAGQY 326

Query: 538 PVECVHTMANICKEAEAV 591
           P E V  MA +C  AE +
Sbjct: 327 PSETVAAMARVCLGAEKI 344


>UniRef50_Q82XE9 Cluster: Pyruvate kinase family; n=130;
           Proteobacteria|Rep: Pyruvate kinase family -
           Nitrosomonas europaea
          Length = 496

 Score =  164 bits (398), Expect = 2e-39
 Identities = 84/186 (45%), Positives = 113/186 (60%)
 Frame = +1

Query: 28  GMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGE 207
           G+L + KG+N  G  +  PA++ KD  D+        D +  SF R+G  +   R ++ E
Sbjct: 149 GILSNNKGINRKGGGLSAPALTAKDLLDIKTSAVIRADYLAVSFPRSGDDIRRARALMQE 208

Query: 208 KGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRV 387
              +  +++KIE  + ++ LD+I+  SD IMVARGDL +E+    V   QK MI      
Sbjct: 209 AQGHSLLMAKIERSEAILALDDILEASDAIMVARGDLAVEVGDAAVPALQKRMIRSAREA 268

Query: 388 GKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMAN 567
            K VI ATQM+ESM+  P PTRAE+SDVANA+LDG D VMLS E+A G YPVE V  MA 
Sbjct: 269 NKLVITATQMMESMISNPIPTRAEVSDVANAVLDGTDAVMLSAESAAGQYPVEAVEAMAR 328

Query: 568 ICKEAE 585
           +C EAE
Sbjct: 329 VCLEAE 334


>UniRef50_Q2TSX0 Cluster: Pyruvate kinase; n=2; cellular
           organisms|Rep: Pyruvate kinase - Phaeodactylum
           tricornutum
          Length = 665

 Score =  163 bits (396), Expect = 4e-39
 Identities = 91/195 (46%), Positives = 120/195 (61%), Gaps = 6/195 (3%)
 Frame = +1

Query: 19  DNAGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGI 198
           D AGM+  RKGVN P   +++  ++ KD+SDL + +  GVD +  SF++  A + EI  +
Sbjct: 297 DVAGMIKDRKGVNTPDSVLEISPLTPKDRSDLEYMLGIGVDWVALSFVQTPADMVEIHAL 356

Query: 199 LGEK---GK-NIKIISKIENHQGMV--NLDEIIAESDGIMVARGDLGIEIPPEKVFLAQK 360
           + EK   G+    +++KIE        NL  I+   +GIMVARGDLG+E PPE V L QK
Sbjct: 357 IDEKLPSGQFKPAVMAKIEKPSCFYDDNLQRIVGLCNGIMVARGDLGVECPPEDVPLLQK 416

Query: 361 TMIARCNRVGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYP 540
            +I  C   G+PVI ATQMLESM++ P PTRAE SDVA AI DGAD +MLS E+A G +P
Sbjct: 417 EIIDECRNQGRPVIVATQMLESMIEVPTPTRAEASDVATAIYDGADAIMLSAESAAGKFP 476

Query: 541 VECVHTMANICKEAE 585
            E V     I    E
Sbjct: 477 EESVAMQQRIINRVE 491


>UniRef50_Q5ZZ75 Cluster: Pyruvate kinase II; n=4; Legionella
           pneumophila|Rep: Pyruvate kinase II - Legionella
           pneumophila subsp. pneumophila (strain Philadelphia 1
           /ATCC 33152 / DSM 7513)
          Length = 474

 Score =  161 bits (392), Expect = 1e-38
 Identities = 85/187 (45%), Positives = 121/187 (64%), Gaps = 1/187 (0%)
 Frame = +1

Query: 28  GMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGE 207
           G+L   KG+N  G  +    ++EKD++DL   +E  VD I  SF+++   + + R ++ +
Sbjct: 150 GVLTDLKGLNRKGGGLAARTLTEKDRNDLRTAIEAEVDYISLSFVKDAEDIRQARALMKD 209

Query: 208 KGKNIK-IISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNR 384
            G  I  II+KIE  + + +L +II E+D IMVARGDLG+E+   +V   QK +I +   
Sbjct: 210 YGAQITPIIAKIERMEALDHLTDIIREADAIMVARGDLGVEVGAAEVPAIQKHIIEQTRL 269

Query: 385 VGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMA 564
           + K VI ATQM+ESM+  P+PTRAE+SDVANAILDG D VMLS ETA G +PV+ +  + 
Sbjct: 270 LDKVVITATQMMESMISNPQPTRAEVSDVANAILDGTDAVMLSAETASGLFPVKVITMVN 329

Query: 565 NICKEAE 585
            IC  AE
Sbjct: 330 KICLSAE 336


>UniRef50_Q0C0E8 Cluster: Pyruvate kinase; n=1; Hyphomonas neptunium
           ATCC 15444|Rep: Pyruvate kinase - Hyphomonas neptunium
           (strain ATCC 15444)
          Length = 474

 Score =  161 bits (392), Expect = 1e-38
 Identities = 81/203 (39%), Positives = 127/203 (62%)
 Frame = +1

Query: 28  GMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGE 207
           G LG +KG  + G  + + A++EKD++DL F +E GVD++  SF++    + E++ I+  
Sbjct: 154 GKLGDKKGFTVRGKALPVRALTEKDRADLDFALEIGVDIVALSFVQTVEDVEEVKAIIAG 213

Query: 208 KGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRV 387
           +     +++K+E    +++L+ I+A +D +MVARGDLG+E  PE+V + Q+ ++     +
Sbjct: 214 RAP---LVAKLEKPAAIIHLEAIVAAADAVMVARGDLGVEFAPEEVPVIQRRIVRVARAL 270

Query: 388 GKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMAN 567
           G+PVI ATQMLESM++   PTRAE SDVA AI  GAD VMLS ETA G +P   V  M+ 
Sbjct: 271 GRPVIVATQMLESMIENSAPTRAEASDVATAIYQGADAVMLSAETAVGRHPATAVAIMSR 330

Query: 568 ICKEAEAVIWHRQLFNDLVSEVK 636
           I +  E    +R+   +   E +
Sbjct: 331 IIRATEGADDYRRSLAEFCGEAQ 353


>UniRef50_A1RX09 Cluster: Pyruvate kinase; n=1; Thermofilum pendens
           Hrk 5|Rep: Pyruvate kinase - Thermofilum pendens (strain
           Hrk 5)
          Length = 464

 Score =  161 bits (390), Expect = 2e-38
 Identities = 82/187 (43%), Positives = 121/187 (64%), Gaps = 1/187 (0%)
 Frame = +1

Query: 28  GMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGE 207
           G +  RK V + G  + LP ++EKD  D+ F V+ G D I  SF+R+ + +  +R IL +
Sbjct: 145 GEVKPRKTVTVRGKDIPLPTITEKDLRDIEFSVKAGFDAIALSFVRSSSDVQRLRDILFD 204

Query: 208 KG-KNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNR 384
            G +++KII+KIE    + +LD I+ +SD  +VARGDL      E+++  Q+ +I+R  R
Sbjct: 205 YGAEDVKIIAKIETKSAVEDLDSILQKSDAALVARGDLANFYGLEEIYSIQRYIISRARR 264

Query: 385 VGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMA 564
            GKP I ATQ+LESM+  P PTR+E+ DV  A+  GAD ++L+GETA G YPVE V+ + 
Sbjct: 265 FGKPSIVATQLLESMISNPLPTRSEVVDVITAVRMGADALLLAGETAAGKYPVESVYWLR 324

Query: 565 NICKEAE 585
            I +EAE
Sbjct: 325 RIVEEAE 331


>UniRef50_P78031 Cluster: Pyruvate kinase; n=6; Mycoplasma|Rep:
           Pyruvate kinase - Mycoplasma pneumoniae
          Length = 508

 Score =  159 bits (386), Expect = 6e-38
 Identities = 86/200 (43%), Positives = 123/200 (61%), Gaps = 1/200 (0%)
 Frame = +1

Query: 40  SRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKG-K 216
           ++K +NLP     +P +S KD  D+ FG+   +D I ASF+     + ++R  L  K  K
Sbjct: 183 TKKRLNLPNADYSIPFLSAKDLRDIDFGLTHQIDYIAASFVNTTENIKQLRDYLASKNAK 242

Query: 217 NIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKP 396
           ++K+I+KIE++  + N+D II  SDGIMVARGDLG+EIP  KV   Q+ MI  C    K 
Sbjct: 243 HVKLIAKIESNHALNNIDGIIKASDGIMVARGDLGLEIPYYKVPYWQRYMIKACRFFNKR 302

Query: 397 VICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMANICK 576
           VI ATQML+S+ K  +PTRAE++DV  A+  G D  MLSGETA G +P+  V+ M  I K
Sbjct: 303 VITATQMLDSLEKNIQPTRAEVTDVYFAVDRGNDATMLSGETANGAFPLNAVYVMKMIDK 362

Query: 577 EAEAVIWHRQLFNDLVSEVK 636
           ++E    ++   N  ++  K
Sbjct: 363 QSETFFDYQYNLNYYMANSK 382


>UniRef50_Q6L281 Cluster: Pyruvate kinase; n=2;
           Thermoplasmatales|Rep: Pyruvate kinase - Picrophilus
           torridus
          Length = 555

 Score =  157 bits (381), Expect = 3e-37
 Identities = 79/183 (43%), Positives = 120/183 (65%)
 Frame = +1

Query: 22  NAGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGIL 201
           ++G L     VN+PG  + L +++++D+  +  G++  V+    SF+++   ++E++  L
Sbjct: 143 DSGSLRDNSRVNVPGKLLRLGSLTDRDRMFIEEGIKNNVNFYALSFVQSRENINELQDYL 202

Query: 202 GEKGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCN 381
            E+  + ++ISKIE   G  N+DEI   SD IMVARGDLG+E+P ++V +AQK +I    
Sbjct: 203 FERNCDAQLISKIETKSGYDNIDEIARASDFIMVARGDLGVEMPLKEVTIAQKKIIDESR 262

Query: 382 RVGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTM 561
           +   P I ATQMLESMV    PTRAE+SD+ NAI+DG D +MLS ETA G YPVE +  +
Sbjct: 263 KYATPTIVATQMLESMVNNDSPTRAEVSDITNAIIDGTDALMLSEETAIGRYPVEAIGYL 322

Query: 562 ANI 570
           ++I
Sbjct: 323 SSI 325


>UniRef50_A7QH42 Cluster: Chromosome chr3 scaffold_95, whole genome
           shotgun sequence; n=1; Vitis vinifera|Rep: Chromosome
           chr3 scaffold_95, whole genome shotgun sequence - Vitis
           vinifera (Grape)
          Length = 573

 Score =  156 bits (378), Expect = 6e-37
 Identities = 80/180 (44%), Positives = 123/180 (68%), Gaps = 3/180 (1%)
 Frame = +1

Query: 76  DLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKG-KNIKIISKIENHQ 252
           +LP +S KD +D+ FG+ +GVD I  SF+++  A+ +++  L  K  K+I +++KIE+ +
Sbjct: 258 ELPTISTKDWADIEFGISEGVDFIAMSFVKDANAIKQLKSYLSNKSSKSIGVLAKIESLE 317

Query: 253 GMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 432
            + +L+EII  SDGIMVARGDLG+EIP E++ + Q  +   C ++ +PVI A+Q+LESMV
Sbjct: 318 SLQHLEEIIEASDGIMVARGDLGVEIPLEQIPVVQAKITHVCRQLNRPVIVASQLLESMV 377

Query: 433 KKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVE--CVHTMANICKEAEAVIWHRQ 606
           + P PTRAE++DV+ A+   AD +MLSGE+A G Y  +  CV  MA+   E    +W R+
Sbjct: 378 EYPTPTRAEVADVSEAVRQYADALMLSGESAIGSYGQKALCVLRMASSRME----LWSRE 433


>UniRef50_Q97ZD7 Cluster: Pyruvate kinase; n=4; Sulfolobaceae|Rep:
           Pyruvate kinase - Sulfolobus solfataricus
          Length = 452

 Score =  154 bits (374), Expect = 2e-36
 Identities = 81/194 (41%), Positives = 121/194 (62%)
 Frame = +1

Query: 28  GMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGE 207
           G+L SRKG+N+P + +    +++ D   L   ++ G D I  SF+ +   + +++  +G+
Sbjct: 134 GILLSRKGINIPNVNLK-SGITDNDLKLLKRALDLGADYIGLSFVISENDVKKVKEFVGD 192

Query: 208 KGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRV 387
           +     +I+KIE  + + NL  I+ ESDGIMVARGDLG+E   E + L Q+ ++      
Sbjct: 193 EAW---VIAKIEKSEALKNLTNIVNESDGIMVARGDLGVETGLENLPLIQRRIVRTSRVF 249

Query: 388 GKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMAN 567
           GKPVI ATQ+L SM+  P PTRAEI D++N+I+ G D +MLS ETA G+YPVE V T+ N
Sbjct: 250 GKPVILATQVLTSMINSPIPTRAEIIDISNSIMQGVDSIMLSDETAIGNYPVESVRTLHN 309

Query: 568 ICKEAEAVIWHRQL 609
           I    E  + HR +
Sbjct: 310 IISNVEKSVKHRPI 323


>UniRef50_Q2FMN4 Cluster: Pyruvate kinase; n=1; Methanospirillum
           hungatei JF-1|Rep: Pyruvate kinase - Methanospirillum
           hungatei (strain JF-1 / DSM 864)
          Length = 500

 Score =  154 bits (374), Expect = 2e-36
 Identities = 84/200 (42%), Positives = 121/200 (60%), Gaps = 1/200 (0%)
 Frame = +1

Query: 22  NAGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGIL 201
           + G +    GV +PG   D+P    +    +  G     D I  SF+ +   + + R +L
Sbjct: 174 SGGTIREGMGVVIPGRRPDVPYAGARFIDYIRQGAALRPDYIALSFVGSAEDIRDARTLL 233

Query: 202 GEKGK-NIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARC 378
             +G  NI +I+KIE  + +  LD+II  +D +MVARGDLG+E+P E+V   QK +I  C
Sbjct: 234 TREGMGNIPLIAKIECRRAVEGLDDIIRHADAVMVARGDLGVELPLEEVPYIQKLIITTC 293

Query: 379 NRVGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHT 558
           ++ G PVI AT+MLESMV + RPTRAE++DVANAI+DG D  MLS ET+ G YP + V  
Sbjct: 294 SQQGIPVITATEMLESMVSRGRPTRAEVTDVANAIVDGTDATMLSAETSVGRYPGQAVVM 353

Query: 559 MANICKEAEAVIWHRQLFND 618
           MA I  E E  + + ++ N+
Sbjct: 354 MARIAIEIEQHLPYLRILNE 373


>UniRef50_Q0AHE3 Cluster: Pyruvate kinase; n=2;
           Nitrosomonadaceae|Rep: Pyruvate kinase - Nitrosomonas
           eutropha (strain C71)
          Length = 483

 Score =  154 bits (373), Expect = 2e-36
 Identities = 87/210 (41%), Positives = 126/210 (60%), Gaps = 1/210 (0%)
 Frame = +1

Query: 25  AGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILG 204
           +G + S  G+N+P     +   ++ D+  L+F +EQ  + I  SF+++   L  +R +L 
Sbjct: 159 SGTVTSGSGINVPESKRSVLIPTDDDRRHLVFALEQQAEWIGVSFVQSADDLIRVRTLL- 217

Query: 205 EKGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNR 384
             G+   +++KIE  Q +V+LD I+A SDG+MVARGDLG+E    ++ L QK +IA  N 
Sbjct: 218 PPGQQPLLMAKIEKRQALVDLDAIMATSDGVMVARGDLGVETDLAEIPLVQKRIIALANA 277

Query: 385 VGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMA 564
             +PVI ATQMLESMV + +PTRAE++DVANA+LDG D VMLS ETA G +PV     + 
Sbjct: 278 QARPVITATQMLESMVTQEQPTRAEVTDVANAMLDGTDGVMLSAETAIGRFPVAAAEILQ 337

Query: 565 NICKEAEAVIWHRQLFNDL-VSEVKPPIDP 651
            +    E     R   + L  SE  P  +P
Sbjct: 338 RVLTATETEYAVRVARDRLRASESTPATNP 367


>UniRef50_A3ALA5 Cluster: Pyruvate kinase; n=3; Oryza sativa|Rep:
           Pyruvate kinase - Oryza sativa subsp. japonica (Rice)
          Length = 548

 Score =  153 bits (371), Expect = 4e-36
 Identities = 76/177 (42%), Positives = 118/177 (66%), Gaps = 1/177 (0%)
 Frame = +1

Query: 79  LPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKG-KNIKIISKIENHQG 255
           LP +S KD +D+ FG+ +GVD I  SF+++   +  ++  L  K  ++IKI +K+E+ + 
Sbjct: 232 LPTLSAKDWADIEFGIAEGVDCIALSFVKDANDIKYLKTYLSRKSLEHIKIFAKVESLES 291

Query: 256 MVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMVK 435
           + NL +II  SDG+MVARGDLG++IP E++   Q+ ++  C R+ KPVI A+Q+LESMV+
Sbjct: 292 LKNLKDIIEASDGVMVARGDLGVQIPLEQIPAIQEAIVDLCRRLNKPVIVASQLLESMVE 351

Query: 436 KPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMANICKEAEAVIWHRQ 606
            P PTRAE++DV+ A+   AD VMLS E+A G YP + +  +    +  E+  W R+
Sbjct: 352 YPTPTRAEVADVSEAVRQYADAVMLSAESAIGAYPQKALAVLRAASERMES--WSRE 406


>UniRef50_A1WED1 Cluster: Pyruvate kinase; n=1; Verminephrobacter
           eiseniae EF01-2|Rep: Pyruvate kinase - Verminephrobacter
           eiseniae (strain EF01-2)
          Length = 496

 Score =  150 bits (364), Expect = 3e-35
 Identities = 86/196 (43%), Positives = 112/196 (57%), Gaps = 4/196 (2%)
 Frame = +1

Query: 28  GMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGIL-- 201
           G L + KG+N  G  +   A++ KD  D+   +    D +  SF +N   +   R +   
Sbjct: 170 GELSNNKGINKKGGGLTASALTAKDMEDIRTAMGFQADYVAVSFPKNATDMEMARQLCTV 229

Query: 202 --GEKGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIAR 375
              E+     +I+KIE  + + +L  I+  SDGIMVARGDL +E+    V   QK MI  
Sbjct: 230 AASEQRHKPGLIAKIERAEAIPHLQAILRVSDGIMVARGDLAVEVGNAAVPALQKKMIRM 289

Query: 376 CNRVGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVH 555
              + K VI ATQM+ESM+  P PTRAE+SDVANA+LDG D VMLS ETA G YP+E V 
Sbjct: 290 ARDMDKLVITATQMMESMITNPVPTRAEVSDVANAVLDGTDAVMLSAETAAGRYPLETVT 349

Query: 556 TMANICKEAEAVIWHR 603
            MA IC  AEA   HR
Sbjct: 350 EMATICAAAEAAEEHR 365


>UniRef50_Q40545 Cluster: Pyruvate kinase isozyme A, chloroplast
           precursor; n=15; Magnoliophyta|Rep: Pyruvate kinase
           isozyme A, chloroplast precursor - Nicotiana tabacum
           (Common tobacco)
          Length = 593

 Score =  149 bits (360), Expect = 9e-35
 Identities = 71/184 (38%), Positives = 119/184 (64%), Gaps = 2/184 (1%)
 Frame = +1

Query: 79  LPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKGKN--IKIISKIENHQ 252
           LP +S KD  D+ FG+ +GVD I  SF+++   +  ++  +  + ++  I +I+KIE+  
Sbjct: 287 LPTISSKDWLDIDFGIAEGVDFIAVSFVKSAEVIKHLKSYIQARARDSDISVIAKIESID 346

Query: 253 GMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 432
            + NL+EII  SDG MVARGDLG +IP E+V   Q+ ++  C ++ +PVI A+Q+LESM+
Sbjct: 347 SLKNLEEIIQASDGAMVARGDLGAQIPLEQVPSEQQKIVQICRQLNRPVIVASQLLESMI 406

Query: 433 KKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMANICKEAEAVIWHRQLF 612
           + P PTRAE++DV+ A+    D +MLSGE+A G +P + +  + ++    E  +W  Q  
Sbjct: 407 EYPIPTRAEVADVSEAVRQRGDALMLSGESAMGQFPEKALTVLRSVSLRIER-MWREQKR 465

Query: 613 NDLV 624
           ++++
Sbjct: 466 HEVI 469


>UniRef50_Q648E3 Cluster: Pyruvate kinase; n=1; uncultured archaeon
           GZfos3D4|Rep: Pyruvate kinase - uncultured archaeon
           GZfos3D4
          Length = 588

 Score =  146 bits (354), Expect = 5e-34
 Identities = 73/132 (55%), Positives = 89/132 (67%)
 Frame = +1

Query: 226 IISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVIC 405
           +I+KIE  Q   N+DEII  +DGIMVARGDLG+++ P++V   QK +I  CN  GKPVI 
Sbjct: 256 VIAKIETKQAWRNIDEIIDVADGIMVARGDLGLQVDPQEVPSIQKKIIKLCNLRGKPVIT 315

Query: 406 ATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMANICKEAE 585
           AT+ML SM   P PTRAE +DV NAILDG D VMLSGET+ G YP   V  M NI ++AE
Sbjct: 316 ATEMLSSMENNPEPTRAESTDVFNAILDGTDAVMLSGETSSGKYPAHAVRMMVNIAEQAE 375

Query: 586 AVIWHRQLFNDL 621
                + L  DL
Sbjct: 376 EYFEQKGLSTDL 387


>UniRef50_A2BLH1 Cluster: Pyruvate kinase; n=1; Hyperthermus
           butylicus DSM 5456|Rep: Pyruvate kinase - Hyperthermus
           butylicus (strain DSM 5456 / JCM 9403)
          Length = 466

 Score =  144 bits (349), Expect = 2e-33
 Identities = 76/185 (41%), Positives = 113/185 (61%)
 Frame = +1

Query: 40  SRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKGKN 219
           SRK + + G    LP +S++D   + F ++ G D I  S +R    +  +R I+  +G +
Sbjct: 155 SRKAIAIRGKDPGLPTLSQRDVEHVKFALDNGFDYIALSHVRTRDDVDALRLIVLREGGD 214

Query: 220 IKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPV 399
             I  KIEN   + NL +II  +D ++VARGDLG+    E+V + Q+ ++A    VGKPV
Sbjct: 215 AGIAVKIENKSAVENLQDIIRAADLVVVARGDLGMTYGLEEVPVLQERIVAAARSVGKPV 274

Query: 400 ICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMANICKE 579
           I ATQ+LESM++ P PTRAE++DV  A+  G D +ML+GETA G YP+E +  +  I   
Sbjct: 275 IVATQLLESMIENPVPTRAEVTDVYVAVRQGVDGLMLTGETAIGRYPIEAIRWLRKIITR 334

Query: 580 AEAVI 594
           AE V+
Sbjct: 335 AEQVL 339


>UniRef50_Q9YEU2 Cluster: Pyruvate kinase; n=1; Aeropyrum
           pernix|Rep: Pyruvate kinase - Aeropyrum pernix
          Length = 458

 Score =  143 bits (347), Expect = 3e-33
 Identities = 74/186 (39%), Positives = 114/186 (61%), Gaps = 1/186 (0%)
 Frame = +1

Query: 28  GMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGE 207
           G+LG RKGV + G   DLP +S KD+  L F  ++GV  ++ SF R+   + ++R ++  
Sbjct: 142 GVLGPRKGVVVRGKEPDLPPLSAKDRRALEFFADKGVSHVYVSFARSAEHVEKVRTVVRR 201

Query: 208 KG-KNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNR 384
            G +  +I +KIE   G+  + EI   SDG+++ARGDLG+    E++   Q+ ++    +
Sbjct: 202 LGLRQARIFAKIEGPSGVSRIGEIAEASDGVIIARGDLGMHYSLEELPEIQELIVWEARK 261

Query: 385 VGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMA 564
             K V+ AT+ L SM++KP PTR+E+ D+  A+L  AD +ML+GETA G YPV+ V  MA
Sbjct: 262 RYKTVVLATEFLSSMIEKPVPTRSEVVDIYQAVLQTADALMLTGETAIGKYPVKSVQWMA 321

Query: 565 NICKEA 582
            I   A
Sbjct: 322 KISSRA 327


>UniRef50_Q9PQV7 Cluster: Pyruvate kinase; n=1; Ureaplasma
           parvum|Rep: Pyruvate kinase - Ureaplasma parvum
           (Ureaplasma urealyticum biotype 1)
          Length = 474

 Score =  140 bits (340), Expect = 2e-32
 Identities = 75/188 (39%), Positives = 113/188 (60%)
 Frame = +1

Query: 22  NAGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGIL 201
           N+  L + K +NLP     LP +S+KD  D+   V+  +  +  SFI N   ++E++ +L
Sbjct: 173 NSYSLKTNKRLNLPDANYSLPFLSKKDIDDINLAVKLKIPYLALSFISNIKQINEVKQLL 232

Query: 202 GEKGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCN 381
            +     K+I+KIE  + + NL+EII  +DGIMVARGDLG+E+P  K+ + Q  ++  C+
Sbjct: 233 KKSSFIPKLIAKIETQEAIDNLEEIIKNTDGIMVARGDLGLEVPFYKIPIYQNKIVELCH 292

Query: 382 RVGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTM 561
           +  K  I ATQML+S+ +   PTRAE++DV  A+    +  MLSGETA G  P+  V  M
Sbjct: 293 KYNKYCIIATQMLDSLERNIIPTRAEVTDVYYAVKQKVNATMLSGETAAGIDPINAVQVM 352

Query: 562 ANICKEAE 585
            +I  E E
Sbjct: 353 KSIILETE 360


>UniRef50_A3DMY9 Cluster: Pyruvate kinase; n=1; Staphylothermus
           marinus F1|Rep: Pyruvate kinase - Staphylothermus
           marinus (strain ATCC 43588 / DSM 3639 / F1)
          Length = 469

 Score =  137 bits (331), Expect = 3e-31
 Identities = 74/196 (37%), Positives = 115/196 (58%)
 Frame = +1

Query: 22  NAGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGIL 201
           N  +L   K + + G  +DLP +SEKD   + + V + +  +  SF+R  + +  +R I+
Sbjct: 144 NDAVLYPHKTLVVFGKEIDLPVLSEKDVDLVNYSVSRKLTYLAISFVRRSSDIVIVRDIV 203

Query: 202 GEKGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCN 381
                 I +I+KIE    + NL +I++ SD I++ARGDLG+    E++   Q+ +     
Sbjct: 204 SRLNGEIGLIAKIETRSAVKNLKDIMSVSDAIIIARGDLGMHYSLEELPGLQRKIAREAI 263

Query: 382 RVGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTM 561
            +GKP I ATQ+LESMV  PRP+R+E+ DV NA+ D  D ++L+ ETA G YPVE V  +
Sbjct: 264 MIGKPSIVATQLLESMVNYPRPSRSEVVDVVNAVYDLVDALLLTDETAIGKYPVESVKWL 323

Query: 562 ANICKEAEAVIWHRQL 609
             I   AE+ I  R++
Sbjct: 324 KRIISSAESSIVERRI 339


>UniRef50_Q22CT0 Cluster: Pyruvate kinase, barrel domain containing
           protein; n=1; Tetrahymena thermophila SB210|Rep:
           Pyruvate kinase, barrel domain containing protein -
           Tetrahymena thermophila SB210
          Length = 747

 Score =  132 bits (320), Expect = 6e-30
 Identities = 62/182 (34%), Positives = 114/182 (62%)
 Frame = +1

Query: 88  VSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKGKNIKIISKIENHQGMVNL 267
           ++ KD +D+   +   +D I  S +R+   +  +R ++GE  + ++I++KI+  + + N 
Sbjct: 439 ITPKDITDINHCINNDIDCICVSNVRSARDIKAVRNLIGED-RGVRIMAKIQTPESVENF 497

Query: 268 DEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMVKKPRP 447
           +EI+  SDG+ +ARG L + +P EK+F  QK MI +C+   KPV+ +  +L+SMV    P
Sbjct: 498 EEIVKASDGVQIARGYLTVHMPVEKLFAKQKEMIHKCHEHLKPVLVSCNILDSMVSSLLP 557

Query: 448 TRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMANICKEAEAVIWHRQLFNDLVS 627
           T  E+ +++N + D  D ++LS ET+ G++PV+ + T++ IC EAEA+   ++L N   S
Sbjct: 558 TMCEVGEISNLVNDYVDNIVLSSETSCGNHPVQAIKTLSRICVEAEALRIMKRLQNPSHS 617

Query: 628 EV 633
           ++
Sbjct: 618 DI 619


>UniRef50_Q8IJ37 Cluster: Pyruvate kinase; n=7; Plasmodium|Rep:
           Pyruvate kinase - Plasmodium falciparum (isolate 3D7)
          Length = 745

 Score =  128 bits (309), Expect = 1e-28
 Identities = 67/123 (54%), Positives = 82/123 (66%), Gaps = 1/123 (0%)
 Frame = +1

Query: 220 IKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCN-RVGKP 396
           I IISKIE    + N++ II  SDGIM+ARGDLGIE     + + QK +I  C  +  KP
Sbjct: 442 IAIISKIEKPSAIKNIENIIKLSDGIMIARGDLGIETNLSNLPILQKKLINLCRIKYNKP 501

Query: 397 VICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMANICK 576
           VI ATQM+ESM   P PTRAE++DVA A+ DG+DCVMLS ETA G YP+  V T   I K
Sbjct: 502 VIVATQMMESMRFLPSPTRAEVTDVATALYDGSDCVMLSAETATGQYPILTVSTQNKIIK 561

Query: 577 EAE 585
           + E
Sbjct: 562 DVE 564



 Score = 40.7 bits (91), Expect = 0.036
 Identities = 20/60 (33%), Positives = 35/60 (58%)
 Frame = +1

Query: 28  GMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGE 207
           G L S+KG  +P + + +  +SEKD  D+LF + + VD +  SF++    L  +R I+ +
Sbjct: 259 GKLYSKKGFCIPNMIMPIDVLSEKDIKDILFCINEEVDFLGYSFVQTEYDLIFLRNIIND 318


>UniRef50_Q22AI0 Cluster: Pyruvate kinase, barrel domain containing
            protein; n=1; Tetrahymena thermophila SB210|Rep: Pyruvate
            kinase, barrel domain containing protein - Tetrahymena
            thermophila SB210
          Length = 837

 Score =  126 bits (305), Expect = 4e-28
 Identities = 64/184 (34%), Positives = 106/184 (57%)
 Frame = +1

Query: 88   VSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKGKNIKIISKIENHQGMVNL 267
            +S KD +D+   +   +D +  S +R    +  ++     + K  KII+KI+  +G+ N 
Sbjct: 532  ISAKDITDITNALNHDIDSVCVSNVRTAEDIRVVKRHC--QSKQTKIIAKIQTLEGVQNY 589

Query: 268  DEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMVKKPRP 447
            DEI+  SD +++ARG L + IP EK+   QK +I + N   KPV+ +  +L+SMV    P
Sbjct: 590  DEILKVSDAVLIARGYLTVHIPVEKLHFKQKELIQKSNESLKPVLVSCNILDSMVSSLLP 649

Query: 448  TRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMANICKEAEAVIWHRQLFNDLVS 627
            T  E+ +++N + D  D ++LSGET+ G YP++ V T++ IC E EA    RQ+  +L  
Sbjct: 650  TTCEVGEISNLVSDYVDAIILSGETSYGMYPIQAVETLSRICMETEA----RQILKNLND 705

Query: 628  EVKP 639
              +P
Sbjct: 706  TTRP 709


>UniRef50_UPI0000DB6F59 Cluster: PREDICTED: similar to Pyruvate
           kinase CG7070-PB, isoform B; n=1; Apis mellifera|Rep:
           PREDICTED: similar to Pyruvate kinase CG7070-PB, isoform
           B - Apis mellifera
          Length = 538

 Score =  121 bits (292), Expect = 2e-26
 Identities = 66/230 (28%), Positives = 127/230 (55%)
 Frame = +1

Query: 28  GMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGE 207
           G++   K + L    V LP +SEKD + + +      D +  + +RN   L+ I+    E
Sbjct: 199 GIVKDGKLIQLLDSLVPLPQISEKDIAHVKWASHLECDFLIMNHVRNEKVLYTIKSRFKE 258

Query: 208 KGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRV 387
              +++IISKI + QG+ NLDEI+  +D I++ R  + +E+  +K+FL +K +IA+C ++
Sbjct: 259 M--SMRIISKISSQQGLENLDEILNAADAILLDRKGIEVEVGDKKLFLVEKIIIAKCIKM 316

Query: 388 GKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMAN 567
           GKP+I + ++ +   K       +++ +ANA+L+G D ++L   +   +   + +  +  
Sbjct: 317 GKPIILSFEVCDENDK----VNIDMNLIANAVLNGIDAILLKTGSLNVNDTSQLIKDIDI 372

Query: 568 ICKEAEAVIWHRQLFNDLVSEVKPPIDPXXXXXXXXXXXXTKCLASAIVV 717
           +C+EAE   W +++F++L  ++  PIDP             K  A+AI++
Sbjct: 373 VCREAECARWQKEIFDELSYKIPIPIDPLHSIIIGGVNISLKSNAAAIII 422


>UniRef50_Q7QVW2 Cluster: Pyruvate kinase; n=1; Giardia lamblia ATCC
           50803|Rep: Pyruvate kinase - Giardia lamblia ATCC 50803
          Length = 553

 Score =  118 bits (284), Expect = 1e-25
 Identities = 71/192 (36%), Positives = 107/192 (55%), Gaps = 6/192 (3%)
 Frame = +1

Query: 28  GMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGE 207
           G LG+RKG+ +P   + L  +S KD  D+      G+D I  SF++  A + E R  + +
Sbjct: 188 GKLGARKGITIPTRILPLSGLSPKDLGDIRNACRLGMDWIALSFVQTKADVIEARDYIAK 247

Query: 208 -KGKNI-----KIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMI 369
              +N      ++ SKIE    ++++D+I   SD +MVARGDL IE    KV   QK + 
Sbjct: 248 LHAENPASFCPRVCSKIEKPTAVLDIDDIALLSDMLMVARGDLAIETCLSKVCSIQKYIC 307

Query: 370 ARCNRVGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVEC 549
            R    G   + ATQM+ES+++   PTRAE++DVA+   DGA+ V+++ ETA G  PV  
Sbjct: 308 ERARYHGCQAMVATQMVESLIENTVPTRAEVTDVASVCFDGANSVLVTAETAAGHDPVNV 367

Query: 550 VHTMANICKEAE 585
           V  + +I    E
Sbjct: 368 VKVLRSILTTTE 379


>UniRef50_A3H760 Cluster: Pyruvate kinase; n=1; Caldivirga
           maquilingensis IC-167|Rep: Pyruvate kinase - Caldivirga
           maquilingensis IC-167
          Length = 456

 Score =  118 bits (284), Expect = 1e-25
 Identities = 61/186 (32%), Positives = 101/186 (54%)
 Frame = +1

Query: 28  GMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGE 207
           G++ + K + +      LP + ++DK  +    +  ++ +  S +R+   +   R  L  
Sbjct: 140 GIIRTHKSITIMNKDYPLPILGDRDKEAIKVAAKYNLEYLGLSHVRSVEDIESTREYLRS 199

Query: 208 KGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRV 387
              +  II K+E    + ++ +I   +D +MVARGDLG+    E+V   Q+ +I   +  
Sbjct: 200 LNYSPMIIVKVETASAIRSIKDIACNADYVMVARGDLGMVFNLEEVPKIQEKIITAAHSC 259

Query: 388 GKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMAN 567
           GKPV+ ATQ+LESMV  P PTRAE+ D+  ++L G D ++L+ ET  G+YPVE V  +  
Sbjct: 260 GKPVMVATQLLESMVNNPVPTRAEVVDIMTSVLQGVDSLLLTDETTMGNYPVEAVEWLRR 319

Query: 568 ICKEAE 585
           I    E
Sbjct: 320 IVSNYE 325


>UniRef50_Q4N603 Cluster: Pyruvate kinase; n=2; Theileria|Rep:
           Pyruvate kinase - Theileria parva
          Length = 699

 Score =  116 bits (278), Expect = 8e-25
 Identities = 61/123 (49%), Positives = 77/123 (62%), Gaps = 1/123 (0%)
 Frame = +1

Query: 205 EKGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNR 384
           E    + II KIE    + ++ EI+  SDG+MVARGDLGIE     + + QK +I  C  
Sbjct: 407 ENLSGVGIIPKIEKQAALDDIHEILKVSDGLMVARGDLGIETDLANLPIVQKRLIQLCRV 466

Query: 385 V-GKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTM 561
           V  KP I ATQMLE+M   P PTRAE+SDV+NA+ DGAD VMLS E+A G YP   V+  
Sbjct: 467 VYRKPCIVATQMLETMRSSPTPTRAEVSDVSNAVFDGADAVMLSAESATGHYPKASVNVQ 526

Query: 562 ANI 570
             +
Sbjct: 527 RRV 529



 Score = 39.9 bits (89), Expect = 0.062
 Identities = 19/58 (32%), Positives = 34/58 (58%)
 Frame = +1

Query: 34  LGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGE 207
           L SRKG ++P + + +  + EKD  D +F +  GVD +  SF++N + +  +  IL +
Sbjct: 293 LSSRKGFSVPKVVLPIEFLDEKDVKDAIFCLGIGVDFLGVSFVQNKSDILYLINILND 350


>UniRef50_A7PC98 Cluster: Chromosome chr2 scaffold_11, whole genome
           shotgun sequence; n=1; Vitis vinifera|Rep: Chromosome
           chr2 scaffold_11, whole genome shotgun sequence - Vitis
           vinifera (Grape)
          Length = 475

 Score =  115 bits (276), Expect = 1e-24
 Identities = 55/97 (56%), Positives = 70/97 (72%)
 Frame = +1

Query: 298 MVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMVKKPRPTRAEISDVAN 477
           MVARGDLG E+P E+V L Q+ +I RC+ + KPVI AT MLESM+  P PTRAE+SD+A 
Sbjct: 243 MVARGDLGAELPIEEVPLLQEDIIRRCHSMQKPVIVATNMLESMINHPTPTRAEVSDIAI 302

Query: 478 AILDGADCVMLSGETAKGDYPVECVHTMANICKEAEA 588
           A+ +GAD VMLSGETA G YP++ V  M  +    E+
Sbjct: 303 AVREGADAVMLSGETAHGKYPLKAVKVMHTVALRTES 339



 Score = 40.7 bits (91), Expect = 0.036
 Identities = 21/56 (37%), Positives = 33/56 (58%), Gaps = 1/56 (1%)
 Frame = +1

Query: 22  NAGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASF-IRNGAALHE 186
           + G L SR+ +N+ G    LP++++KD  D+ FGV+  VD    SF  +N   +HE
Sbjct: 112 DGGELKSRRHLNVRGKSATLPSITDKDWEDIKFGVDNQVDFYAVSFWEKNYHMMHE 167


>UniRef50_A7APT5 Cluster: Pyruvate kinase family protein; n=1;
           Babesia bovis|Rep: Pyruvate kinase family protein -
           Babesia bovis
          Length = 693

 Score =  115 bits (276), Expect = 1e-24
 Identities = 61/123 (49%), Positives = 78/123 (63%), Gaps = 1/123 (0%)
 Frame = +1

Query: 220 IKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRV-GKP 396
           I II KIE    + +++ I+  SDG+M+ARGDLG+E     + + QK +I  C  V  KP
Sbjct: 403 IAIIPKIEKQPALDDINGILEVSDGMMIARGDLGVETEITNLPVIQKRLIQLCRLVYHKP 462

Query: 397 VICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMANICK 576
           VI ATQMLESM   P+P+RAE +D ANA+ DGAD VMLS E+A G YP   V T   +  
Sbjct: 463 VIVATQMLESMKSNPKPSRAEATDCANAVYDGADAVMLSAESATGAYPAHSVRTQRLLLY 522

Query: 577 EAE 585
            AE
Sbjct: 523 NAE 525



 Score = 43.2 bits (97), Expect = 0.007
 Identities = 19/60 (31%), Positives = 33/60 (55%)
 Frame = +1

Query: 22  NAGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGIL 201
           N G+L SRKG  +P + + +   SEKD  D +F    G+D +  SF++    +  ++ I+
Sbjct: 280 NDGVLSSRKGFAVPNVAITVDLFSEKDVKDTIFSYALGLDFLGVSFVQRMTDILYLKNII 339


>UniRef50_Q8TGR8 Cluster: Uncharacterized protein YAL037C-B; n=1;
           Saccharomyces cerevisiae|Rep: Uncharacterized protein
           YAL037C-B - Saccharomyces cerevisiae (Baker's yeast)
          Length = 324

 Score =  115 bits (276), Expect = 1e-24
 Identities = 57/174 (32%), Positives = 101/174 (58%)
 Frame = -3

Query: 618 VIEELPVPDYSFSLLANVGHGVNTLDRIVALGSLPGEHHAVSSVEDGVGYVRDLGSGGTG 439
           VI    V D  FS  +   H  N +D +V LG    +H+ VS+++D V  + +  SG + 
Sbjct: 139 VIVVWQVSDSLFSNDSGFSHSGNGVDWVVTLGGFTRQHNTVSTIQDSVTDIGNFSSGWSW 198

Query: 438 LLNHGFQHLSRTDHWFSNPIASGDHGLLGEEYLFWRDLDTQISASNHDTIGFSYNLV*ID 259
           +++HGFQHL  TD+W ++ +   +  LL  +  +  D +TQ+++ NH+T+    + V + 
Sbjct: 199 VVSHGFQHLGSTDNWLTSQVRLSNQFLLDSQDFWGWDFNTQVTSGNHNTVSDLQDFVEVV 258

Query: 258 HSLVIFDLGDDLDVLAFFAEDAANLVQRGAVADE*RENHINALFDAEEQVRLVL 97
           ++L++F+L +DLDVL  F +D ++       +DE  E+H++ + D E Q+ LVL
Sbjct: 259 NTLLVFNLDNDLDVLTLFTQDFSDGQNIVGGSDERSEDHVDTVLDTESQIFLVL 312


>UniRef50_Q9V2V8 Cluster: Pyruvate kinase; n=1; Thermoproteus
           tenax|Rep: Pyruvate kinase - Thermoproteus tenax
          Length = 446

 Score =  111 bits (268), Expect = 1e-23
 Identities = 62/190 (32%), Positives = 103/190 (54%), Gaps = 2/190 (1%)
 Frame = +1

Query: 22  NAGMLGSRKGVNLPGIPVDLPAVSEKDKSDL--LFGVEQGVDMIFASFIRNGAALHEIRG 195
           ++G++ S K + + G    +    E+D   L  L      VD +  S +R+GA + ++R 
Sbjct: 140 SSGVISSNKAIVVKGKEYHIEQPVEEDIRALQTLSRFRDDVDYVALSLVRDGADVRKMRS 199

Query: 196 ILGEKGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIAR 375
           ++ E G    I++KIE    +  ++EII  +D I++ARGDL +    E +   Q+ ++ R
Sbjct: 200 VVEEAGLTSGIMAKIETKSAVDKIEEIINAADYIVIARGDLALHYGLEYIPKVQRLLVER 259

Query: 376 CNRVGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVH 555
               G+PV  ATQ+L+SM     PTRAE++DV      G D + L+ ETA G++P+E V 
Sbjct: 260 SLSAGRPVAVATQLLDSMQTNTTPTRAEVNDVYTTASLGVDSLWLTNETASGEHPLEAVD 319

Query: 556 TMANICKEAE 585
            +  I  + E
Sbjct: 320 WLRRIVSQVE 329


>UniRef50_Q8ZYE0 Cluster: Pyruvate kinase; n=4; Pyrobaculum|Rep:
           Pyruvate kinase - Pyrobaculum aerophilum
          Length = 461

 Score =  109 bits (263), Expect = 5e-23
 Identities = 59/191 (30%), Positives = 103/191 (53%), Gaps = 2/191 (1%)
 Frame = +1

Query: 19  DNAGMLGSRKGVNLPGIPVDLPAVSEKDKSDL--LFGVEQGVDMIFASFIRNGAALHEIR 192
           +++G++   K + + G   D+   +E+D   L  +  +   +D +  S  ++   +  +R
Sbjct: 156 ESSGVITGGKAIVVEGKDYDISTPAEEDVEALKAISPIRDNIDYVAISLAKSCKDVDSVR 215

Query: 193 GILGEKGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIA 372
            +L E G   ++  KIE    + NL+E++  SD ++VARGDLG+    + + + Q+ ++ 
Sbjct: 216 SLLTELGFQSQVAVKIETKGAVNNLEELVQCSDYVVVARGDLGLHYGLDALPIVQRRIVH 275

Query: 373 RCNRVGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECV 552
              + GKP+  ATQ+L+SM   P PTRAEI+DV      G D + L+ ETA G YP+  V
Sbjct: 276 TSLKYGKPIAVATQLLDSMQSSPIPTRAEINDVFTTASMGVDSLWLTNETASGKYPLAAV 335

Query: 553 HTMANICKEAE 585
             ++ I    E
Sbjct: 336 SWLSRILMNVE 346


>UniRef50_Q090R5 Cluster: Pyruvate kinase; n=1; Stigmatella
           aurantiaca DW4/3-1|Rep: Pyruvate kinase - Stigmatella
           aurantiaca DW4/3-1
          Length = 515

 Score =  108 bits (260), Expect = 1e-22
 Identities = 46/103 (44%), Positives = 72/103 (69%)
 Frame = +1

Query: 28  GMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGE 207
           G L + KG+NLPG+ V   A++ KD+ DL+FG+++GVD +  SF+R  A +   R  + E
Sbjct: 159 GTLKNNKGINLPGVAVRADALTPKDREDLVFGIKEGVDFLALSFVRQPADIELARQAMAE 218

Query: 208 KGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPP 336
            G+ + I++K+E  + +  LD I+ ++DG+MVARGDLG+EIPP
Sbjct: 219 AGRQVPIVAKLEKPEAIARLDAILDKTDGVMVARGDLGVEIPP 261



 Score = 38.3 bits (85), Expect = 0.19
 Identities = 29/88 (32%), Positives = 34/88 (38%)
 Frame = +3

Query: 318 GYRDPSRKGIPRPEDHDRQMQSGWKTSDLCDSNAGIHG*EAPSHQSRDL*RSQRHPRRS* 497
           G   P R G  RPE H   +Q          ++A +   E P H      R QR  RR  
Sbjct: 256 GVEIPPRGGAGRPEGHHPALQPARPAGHRGHADAQLDDREPPPHARGGQRRGQRRVRRGG 315

Query: 498 LRDALRGDCQGRLSCRVCSHHGQHLQGG 581
              AL  D Q  L  RV +  G H  GG
Sbjct: 316 RGHALGRDGQRPLPHRVGADDGPHRPGG 343


>UniRef50_A0BDA7 Cluster: Pyruvate kinase; n=3; Alveolata|Rep:
           Pyruvate kinase - Paramecium tetraurelia
          Length = 700

 Score =  107 bits (257), Expect = 3e-22
 Identities = 57/166 (34%), Positives = 91/166 (54%)
 Frame = +1

Query: 88  VSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKGKNIKIISKIENHQGMVNL 267
           ++ KD +D         D I  S +     +HE++ +LG    NI+I  +I   +G+ N 
Sbjct: 292 ITSKDINDFTIAKRLDFDSITLSNVSRPEEVHELKHLLGSS-TNIQIFVRITTQEGINNF 350

Query: 268 DEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMVKKPRP 447
           D+I+  +DG ++AR  L      E V   Q  MI  C ++ KPV+ +TQ+LESM+ +  P
Sbjct: 351 DKIMEIADGCIIARAYLATWAQIEDVVQMQHDMILNCRKLVKPVLISTQILESMLTQTNP 410

Query: 448 TRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMANICKEAE 585
           T AE+ D+A+ +    D +MLSGET  G++P++ V  +A I    E
Sbjct: 411 TFAEMGDIADVVEQHIDGIMLSGETTYGNHPIKVVQALARISTNIE 456


>UniRef50_Q5M6U9 Cluster: Pyruvate kinase; n=2; Campylobacter
           jejuni|Rep: Pyruvate kinase - Campylobacter jejuni
          Length = 319

 Score =  107 bits (256), Expect = 4e-22
 Identities = 66/177 (37%), Positives = 99/177 (55%)
 Frame = +1

Query: 22  NAGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGIL 201
           + G+L + KG+++  +  ++P + EKDK  +    E  +  + ASF+R  + + EI+ +L
Sbjct: 129 STGLLLNNKGMHVRNLHDNIPFLFEKDKELIKLCNEFDIAYVGASFVRKASDIQEIKQVL 188

Query: 202 GEKGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCN 381
                N KIISKIE  + + NL  I+ E + I++ RGDL  EI  EK+   Q  ++   +
Sbjct: 189 HS---NTKIISKIETLEAVNNLYSILQEVEYILIDRGDLSTEIGIEKIPRFQNYIVEMAH 245

Query: 382 RVGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECV 552
                V  ATQ+L++M +KP PT AEI D+ N    G   V LS ETA G Y  ECV
Sbjct: 246 HNAIKVFLATQILKNMEEKPIPTIAEIDDLYNIAKSGVFGVQLSEETAVGHYVEECV 302


>UniRef50_UPI000155B976 Cluster: PREDICTED: similar to pyruvate
           kinase, liver and RBC, partial; n=1; Ornithorhynchus
           anatinus|Rep: PREDICTED: similar to pyruvate kinase,
           liver and RBC, partial - Ornithorhynchus anatinus
          Length = 339

 Score =  106 bits (254), Expect = 6e-22
 Identities = 46/80 (57%), Positives = 64/80 (80%)
 Frame = +1

Query: 19  DNAGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGI 198
           ++ G LGSRKGVN+PG  +DLPAVSE+D  DL FG++Q VD++FASF+R  A + E+R  
Sbjct: 60  ESGGRLGSRKGVNVPGAVLDLPAVSEQDARDLRFGLDQDVDIVFASFVRKAADVAEVRAA 119

Query: 199 LGEKGKNIKIISKIENHQGM 258
           LG +G+ +K+ISKIENH+G+
Sbjct: 120 LGPRGRAVKVISKIENHEGV 139


>UniRef50_UPI0000D56D72 Cluster: PREDICTED: similar to CG7070-PB,
           isoform B; n=1; Tribolium castaneum|Rep: PREDICTED:
           similar to CG7070-PB, isoform B - Tribolium castaneum
          Length = 535

 Score =  104 bits (250), Expect = 2e-21
 Identities = 67/234 (28%), Positives = 123/234 (52%)
 Frame = +1

Query: 19  DNAGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGI 198
           + AG+L     V LP +P+ LP     +K  +    +  +D++F       + L  ++  
Sbjct: 213 EKAGLLTDNLSVKLPNVPITLPKTESHEKL-IQIKEKCEIDIVFVG----PSKLDMVKET 267

Query: 199 LGEKGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARC 378
           LG     + II+K+E    +   D ++ +SDG+++  G+  +    E+VFL QK++IA C
Sbjct: 268 LGP---TVLIIAKLEYASSVDFFDSLVKKSDGVIID-GEKLMATSKERVFLVQKSVIANC 323

Query: 379 NRVGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHT 558
           N++GKPV+ A       +     T++ ++D+AN ++DG D ++L  +        + + +
Sbjct: 324 NKLGKPVLAA-------INCHAVTKSIVNDIANTVIDGIDGLLLPPDP-------DLIES 369

Query: 559 MANICKEAEAVIWHRQLFNDLVSEVKPPIDPXXXXXXXXXXXXTKCLASAIVVI 720
           ++ ICK AE  ++ ++LF+DLVS   PPI+P             K  A+AI++I
Sbjct: 370 ISLICKAAEGAVYQKRLFDDLVSLKPPPIEPIISIAISAVEASFKSNAAAIILI 423


>UniRef50_Q9M3B6 Cluster: Pyruvate kinase; n=1; Arabidopsis
            thaliana|Rep: Pyruvate kinase - Arabidopsis thaliana
            (Mouse-ear cress)
          Length = 710

 Score =  103 bits (248), Expect = 3e-21
 Identities = 75/186 (40%), Positives = 102/186 (54%), Gaps = 7/186 (3%)
 Frame = +1

Query: 34   LGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGE-K 210
            LGS K +N+P   +    ++ KD  DL + V    DM+  SFIR+   +  +R  L + K
Sbjct: 516  LGSEKSINIPQSDIHFKGLTSKDIKDLDY-VASHADMVGISFIRDVHDITVLRQELKKRK 574

Query: 211  GKNIKIISKIENHQGMVNLDEIIAESD------GIMVARGDLGIEIPPEKVFLAQKTMIA 372
              ++ I+ KIE   G  NL  I+ E+       GIM+ARGDL +E   E++   Q+ +IA
Sbjct: 575  LDDLGIVLKIETKSGFKNLSLILLEAMKCSNPLGIMIARGDLAVECGWERLANMQEEIIA 634

Query: 373  RCNRVGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECV 552
             C     PVI ATQ+LES+VK   PTRAEI+D ANA    A CVML+    KG   VE V
Sbjct: 635  ICKAARVPVIMATQVLESLVKSGVPTRAEITDAANA--KRASCVMLN----KGKNIVEAV 688

Query: 553  HTMANI 570
              +  I
Sbjct: 689  SMLDTI 694


>UniRef50_Q7NJ33 Cluster: Pyruvate kinase; n=1; Gloeobacter
           violaceus|Rep: Pyruvate kinase - Gloeobacter violaceus
          Length = 501

 Score =  103 bits (246), Expect = 6e-21
 Identities = 69/196 (35%), Positives = 107/196 (54%), Gaps = 7/196 (3%)
 Frame = +1

Query: 19  DNAGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGI 198
           D    L + KG+N P   + L  +SE+D   L F V +  D++  SF      +  ++  
Sbjct: 295 DKGSRLAADKGINFPESRLKLRGLSEQDLEHLDF-VARRADIVGMSFANEPEDVFALQAA 353

Query: 199 LGEKGK-NIKIISKIENHQGMVNLDEIIAES-----DGIMVARGDLGIEIPPEKVFLAQK 360
           LGE+G  ++ I+ KIE  +G   L  +I  +      G+M+ARGDL +E   E+    Q+
Sbjct: 354 LGERGAGHLGILLKIETRRGFEQLPRLILAAMRSYPAGVMIARGDLAVECGWERTAEVQE 413

Query: 361 TMIARCNRVGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYP 540
            ++  C     PV+ ATQ+LE + KK  P+RAEI+D   A+   A+CVML+    KG + 
Sbjct: 414 EILWLCEAGHMPVVWATQVLEKLAKKGLPSRAEITDA--AMSQRAECVMLN----KGPHI 467

Query: 541 VECVHTMANI-CKEAE 585
           VE VH++A+I C+  E
Sbjct: 468 VEAVHSLADILCRMQE 483


>UniRef50_Q8XLL6 Cluster: Pyruvate kinase; n=3; Clostridium
           perfringens|Rep: Pyruvate kinase - Clostridium
           perfringens
          Length = 364

 Score =  101 bits (242), Expect = 2e-20
 Identities = 66/194 (34%), Positives = 104/194 (53%), Gaps = 5/194 (2%)
 Frame = +1

Query: 28  GMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGE 207
           G++   KG NLP +      VSEKD  D+ F ++  VD+I  S+        E + I+ +
Sbjct: 161 GVVRKEKGCNLPNLDRKNWGVSEKDLEDIKFAIDNKVDIIDYSYCSYMEECREFKNIVFK 220

Query: 208 KGKNIKII----SKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIAR 375
             K+ + I     KIE ++G+ N+ E+  E DGI++ARGDL  EI    V + Q+ ++  
Sbjct: 221 NLKSNQFIPKLWGKIETNEGINNIKEVAKELDGIVIARGDLTAEIGILNVPIVQEKILYA 280

Query: 376 CNRVGKPVICATQMLESM-VKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECV 552
                K +I AT +L S+  K+ +PT  E+SD+ + I  GA   ML+GET+ G+     V
Sbjct: 281 LKNENKSIIVATNVLSSIRNKQNKPTINELSDIYHFIRCGATGFMLTGETSTGENEEYVV 340

Query: 553 HTMANICKEAEAVI 594
            T+ N  K  E ++
Sbjct: 341 TTLKNSIKYYEKLL 354


>UniRef50_A7QTW5 Cluster: Chromosome undetermined scaffold_171,
           whole genome shotgun sequence; n=1; Vitis vinifera|Rep:
           Chromosome undetermined scaffold_171, whole genome
           shotgun sequence - Vitis vinifera (Grape)
          Length = 622

 Score = 99.1 bits (236), Expect = 1e-19
 Identities = 70/184 (38%), Positives = 104/184 (56%), Gaps = 8/184 (4%)
 Frame = +1

Query: 34  LGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKG 213
           LG+ K +N+P   +    ++ KD  DL F V    DM+  SFIR+   +  +R  L EK 
Sbjct: 422 LGAEKSINIPESNIRFEGLTTKDLMDLEF-VAAHADMVGISFIRDVRDIVVLRAEL-EKR 479

Query: 214 K--NIKIISKIENHQGMVNLDEIIAESD------GIMVARGDLGIEIPPEKVFLAQKTMI 369
           K  N+ I+ KIE   G   L  ++ E+       G+M+ARGDL +E   E++   Q+ ++
Sbjct: 480 KLHNLGIVLKIETSSGFDKLPLLLLEAMKSPNPLGVMIARGDLAVECGWERLGDIQEEIL 539

Query: 370 ARCNRVGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVEC 549
           + C+    PVI ATQ+LES+VK   PTRAE++DVAN     A C+ML+    KG + V+ 
Sbjct: 540 SICSAAHVPVIWATQVLESLVKSGVPTRAELTDVANG--RRASCIMLN----KGKHIVDA 593

Query: 550 VHTM 561
           V T+
Sbjct: 594 VSTL 597


>UniRef50_A0BIN1 Cluster: Pyruvate kinase; n=2; Paramecium
           tetraurelia|Rep: Pyruvate kinase - Paramecium
           tetraurelia
          Length = 509

 Score = 96.7 bits (230), Expect = 5e-19
 Identities = 50/166 (30%), Positives = 94/166 (56%)
 Frame = +1

Query: 88  VSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKGKNIKIISKIENHQGMVNL 267
           ++E+D  D+ +  E   D I  S +     + +++  L +K  ++++ ++I        L
Sbjct: 200 MTEQDILDIDYACECNFDSITFSKVNTALDIIKVKERLEQKYPHVQVFARIAEKLKEEQL 259

Query: 268 DEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMVKKPRP 447
           +EII  +DG ++AR  + +  P E V   Q  +I+ C ++ KPV  +T +LESM  + +P
Sbjct: 260 EEIITLADGCIIARSHISMTQPVEDVVKYQTQIISSCRKLFKPVFVSTYILESMSVQLKP 319

Query: 448 TRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMANICKEAE 585
           + A++ D++N +    D ++LSGE + G +PV  V T+ NIC++ E
Sbjct: 320 SFADMGDISNIVKQYIDGILLSGEASFGKFPVLIVQTLNNICRKIE 365


>UniRef50_A3PTF7 Cluster: Pyruvate kinase; n=5; Mycobacterium|Rep:
           Pyruvate kinase - Mycobacterium sp. (strain JLS)
          Length = 615

 Score = 95.1 bits (226), Expect = 2e-18
 Identities = 62/187 (33%), Positives = 106/187 (56%), Gaps = 6/187 (3%)
 Frame = +1

Query: 34  LGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKG 213
           LGS KGVN+P   + + A+++KD  DL   V    D++  SF++  + + ++   L   G
Sbjct: 411 LGSAKGVNVPDTHLPIAALTDKDVEDLATVVAIA-DIVQISFVQRPSDITQLHDELHRLG 469

Query: 214 -KNIKIISKIENHQGMVNLDEIIAESD-----GIMVARGDLGIEIPPEKVFLAQKTMIAR 375
             ++ ++ KIE  +   +L +++  +      G+M+ARGDL +E+  E++   Q+ ++  
Sbjct: 470 GDHLGVVLKIETRRAFEHLPQLLLTAMRRPRVGVMIARGDLAVEVGYERLAEVQEEVLWL 529

Query: 376 CNRVGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVH 555
           C     PVI ATQ+LES+ K   P+RAEISD A    + A+CVML+    KG + V+ V 
Sbjct: 530 CEAAHLPVIWATQVLESLAKSGLPSRAEISDAAMG--ERAECVMLN----KGPHIVDAVV 583

Query: 556 TMANICK 576
            + +I +
Sbjct: 584 VLDDILR 590


>UniRef50_Q062W1 Cluster: Pyruvate kinase; n=1; Synechococcus sp.
           BL107|Rep: Pyruvate kinase - Synechococcus sp. BL107
          Length = 359

 Score = 94.7 bits (225), Expect = 2e-18
 Identities = 65/206 (31%), Positives = 106/206 (51%), Gaps = 3/206 (1%)
 Frame = +1

Query: 28  GMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGE 207
           G     +  ++   P+ L   +E D   +    +     IF SF  +   +   R +   
Sbjct: 150 GTCEKNRAFDIANKPLILKPHTEFDIWAIKESTKHSCPAIFHSFAESAEDIKTTRSLC-- 207

Query: 208 KGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRV 387
           KG++ K+I+KIE+ +G+ ++ EI   SDGI++ RGDL  EI    V +A       C  +
Sbjct: 208 KGQS-KVIAKIESRRGLESIKEIATASDGILIDRGDLSREISISMVPVAVNLATKLCVEI 266

Query: 388 GKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMAN 567
            KP+  AT +L+S++    P+RAEISD+ N +  G   ++L+ E A G  P+E V  + +
Sbjct: 267 EKPIYVATNVLDSLMSNSLPSRAEISDIHNMLTMGVTGMVLAAEVAIGARPIESVQVVNH 326

Query: 568 ICKEAEA-VIWHRQLF--NDLVSEVK 636
           I K  EA  +    +F  NDL +E+K
Sbjct: 327 IRKIVEAQKLGILGIFNSNDLKTELK 352


>UniRef50_A1U5Q4 Cluster: Pyruvate kinase; n=2; Marinobacter
           aquaeolei VT8|Rep: Pyruvate kinase - Marinobacter
           aquaeolei (strain ATCC 700491 / DSM 11845 /
           VT8)(Marinobacter hydrocarbonoclasticus (strain DSM
           11845))
          Length = 626

 Score = 93.5 bits (222), Expect = 5e-18
 Identities = 62/190 (32%), Positives = 105/190 (55%), Gaps = 6/190 (3%)
 Frame = +1

Query: 34  LGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGE-K 210
           L + KG+NLP   +++ +++  D S L F + +  D +  SF+ +   +  +   L   K
Sbjct: 424 LRAGKGMNLPDSQLNVSSLTPTDISHLTF-IAKHADAVQMSFVNSAHDVTLLDEALSRVK 482

Query: 211 GKNIKIISKIENHQGMVNLDEIIAESD-----GIMVARGDLGIEIPPEKVFLAQKTMIAR 375
           G ++ I+ KIE  +G  NL  ++  +      G+M+ARGDL +E   E++   Q+ +++ 
Sbjct: 483 GDHLGIVLKIETRRGFENLPSMLLTAMRRPKVGVMIARGDLAVECGYERLAEVQEEILSV 542

Query: 376 CNRVGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVH 555
           C     PVI ATQ+LE++ +K  P+RAEISD   A    A+CVML+    KG + +E + 
Sbjct: 543 CEAAHVPVIWATQVLENLAQKGMPSRAEISDAVMA--HRAECVMLN----KGPHVIEALG 596

Query: 556 TMANICKEAE 585
            + +I K  E
Sbjct: 597 VLDSILKRME 606


>UniRef50_O58306 Cluster: Putative uncharacterized protein PH0571;
           n=1; Pyrococcus horikoshii|Rep: Putative uncharacterized
           protein PH0571 - Pyrococcus horikoshii
          Length = 181

 Score = 93.1 bits (221), Expect = 6e-18
 Identities = 57/118 (48%), Positives = 73/118 (61%)
 Frame = -1

Query: 587 ASASLQMLAMV*THSTG*SPLAVSPESITQSAPSRMALATSEISALVGRGFLTMDSSI*V 408
           +S +  +LA++ T S G  P AVS ++IT S PS +ALATS  SALVG   + M++SI V
Sbjct: 43  SSVTFAILAIISTASIGNFPTAVSSDNITASVPSSIALATSVTSALVGTFSIVMETSIWV 102

Query: 407 AQITGFPTRLHLAIMVFWARNTFSGGISIPRSPRATMIPSDSAIISSKLTIPW*FSIL 234
           A ITGFP+ L   I +FW   + S GIS PRSP A +IPS +  IS K       SIL
Sbjct: 103 AVITGFPSMLAFLINLFWRIGSCSIGISTPRSPLAIIIPSAAFRISLKFLTASGLSIL 160


>UniRef50_Q5KVI2 Cluster: Pyruvate kinase; n=2; Geobacillus|Rep:
           Pyruvate kinase - Geobacillus kaustophilus
          Length = 660

 Score = 92.3 bits (219), Expect = 1e-17
 Identities = 62/187 (33%), Positives = 107/187 (57%), Gaps = 8/187 (4%)
 Frame = +1

Query: 49  GVNLPG--IPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKGK-N 219
           G++LP   + + +P ++++D   + F + +  D++  SF++    L ++  +L E+G  +
Sbjct: 455 GIHLPDSFLHLTVPPLTDRDLEWIPF-IARWADIVGLSFVQAPHDLRKLYHLLAEQGAGS 513

Query: 220 IKIISKIENHQGMVNLDEIIAE-----SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNR 384
           + +I+KIE    + N   I+ E     + G+M+ARGDL +EI  E +  AQ  ++A C  
Sbjct: 514 LPVIAKIETRAALHNFVRILLEGLKFPAFGVMIARGDLALEIGFEHLAAAQNDVLALCRA 573

Query: 385 VGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMA 564
              PVI ATQ+LE M KK  P+RAEISDV   +   A C+ML+    KG +  E V  ++
Sbjct: 574 AHIPVIWATQVLEQMAKKGIPSRAEISDV--FVGKQAQCIMLN----KGRHIAEAVRLLS 627

Query: 565 NICKEAE 585
           ++ ++ E
Sbjct: 628 SLLEKEE 634


>UniRef50_A0NLM6 Cluster: Pyruvate kinase; n=2;
           Alphaproteobacteria|Rep: Pyruvate kinase - Stappia
           aggregata IAM 12614
          Length = 512

 Score = 92.3 bits (219), Expect = 1e-17
 Identities = 63/181 (34%), Positives = 98/181 (54%), Gaps = 8/181 (4%)
 Frame = +1

Query: 16  QDNAGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGA---ALHE 186
           +D+   +  +KG+NLP   + +  ++ KDK+DL   V    DM+  SF+        L E
Sbjct: 306 KDSGVKIKPQKGINLPDTALGVSPLTAKDKTDLKT-VTALADMVGYSFVSEPDDIDLLEE 364

Query: 187 IRGILGEKGKNIKIISKIENHQGMVNLDEIIAESDG-----IMVARGDLGIEIPPEKVFL 351
               +G     + I++KIE  + + NL  +IA + G     IM+ARGDL  EI  E++  
Sbjct: 365 ALASIGAANHPLGIVAKIERPEAVQNLPALIARASGTRPLAIMIARGDLASEIGFERLAE 424

Query: 352 AQKTMIARCNRVGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKG 531
            Q+ ++  C     PVI ATQ+LES+VK   P+R +++D A A    A+CVML+   A G
Sbjct: 425 MQEEILWICEAASTPVIWATQVLESLVKFGSPSRGDMTDAAMAA--RAECVMLNKGPAVG 482

Query: 532 D 534
           +
Sbjct: 483 E 483


>UniRef50_A4VPY3 Cluster: Pyruvate kinase; n=1; Pseudomonas stutzeri
            A1501|Rep: Pyruvate kinase - Pseudomonas stutzeri (strain
            A1501)
          Length = 625

 Score = 91.5 bits (217), Expect = 2e-17
 Identities = 65/207 (31%), Positives = 106/207 (51%), Gaps = 6/207 (2%)
 Frame = +1

Query: 34   LGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGE-K 210
            L S KG+N P   + + A +E D   L F  +   D++  SF  +   + E+   L    
Sbjct: 417  LASDKGINFPDNALPVRAPTEDDIETLAFAAKHA-DIVQMSFANSAEDVIELIDHLERLD 475

Query: 211  GKNIKIISKIENHQGMVNLDEIIAESD-----GIMVARGDLGIEIPPEKVFLAQKTMIAR 375
              ++ ++ KIE   G  NL +++         G+M+ARGDL +E   E++   Q+ M+  
Sbjct: 476  ATHLGVVLKIETRAGFENLPKMLLAGMRLPRFGVMIARGDLAVETGFERLAEIQEEMLCL 535

Query: 376  CNRVGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVH 555
            C     PVI ATQ+LES+ KK  P R+EI+D A ++   A+CVML+    KG Y ++ V 
Sbjct: 536  CEAAHVPVIWATQVLESLAKKGAPARSEITDAAMSV--RAECVMLN----KGPYILKAVT 589

Query: 556  TMANICKEAEAVIWHRQLFNDLVSEVK 636
            T+ ++ +       HR    DL+  ++
Sbjct: 590  TLNDVLRRMRE---HRAKKRDLLRSLQ 613


>UniRef50_A4ARB8 Cluster: Pyruvate kinase; n=1; Flavobacteriales
           bacterium HTCC2170|Rep: Pyruvate kinase -
           Flavobacteriales bacterium HTCC2170
          Length = 624

 Score = 91.1 bits (216), Expect = 3e-17
 Identities = 62/195 (31%), Positives = 99/195 (50%), Gaps = 5/195 (2%)
 Frame = +1

Query: 16  QDNAGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRG 195
           +D    L + KG+NLP   + +  ++ KD+ D+ F + +  D +  SF+ +   + ++  
Sbjct: 409 KDKGSKLKADKGINLPKSDLKISGLTNKDREDIKF-IAKHADAVNFSFVNSKEDILDLYN 467

Query: 196 ILGEKGKNIKIISKIENHQGMVNLDEIIAESD-----GIMVARGDLGIEIPPEKVFLAQK 360
            L +    I +I KIE  +G  NL  I+  +      G+M ARGDL IE   +     Q+
Sbjct: 468 ELDKLDSKIGVILKIETEKGFSNLPSILLTAMRSFPIGVMTARGDLAIETGWKNFASIQQ 527

Query: 361 TMIARCNRVGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYP 540
            ++  C     P I ATQ+LE++ KK  P+RAEI+D   A+   A+CVML+    KG Y 
Sbjct: 528 EIMRICAAAHIPNIWATQVLENLAKKGTPSRAEITDA--ALAQQAECVMLN----KGYYI 581

Query: 541 VECVHTMANICKEAE 585
              V  +  I +  E
Sbjct: 582 QRAVKMLDKILRRME 596


>UniRef50_A6LTB0 Cluster: Pyruvate kinase; n=1; Clostridium
           beijerinckii NCIMB 8052|Rep: Pyruvate kinase -
           Clostridium beijerinckii NCIMB 8052
          Length = 340

 Score = 89.8 bits (213), Expect = 6e-17
 Identities = 56/185 (30%), Positives = 96/185 (51%), Gaps = 4/185 (2%)
 Frame = +1

Query: 28  GMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGE 207
           G++   KG N+  +      ++E DK  +++GV   VD+I  SF+     + +++  L  
Sbjct: 149 GVIRKWKGCNIKNLERKELPLNENDKDAIVWGVNNKVDIICQSFVEEKKDIDDVKLFLNN 208

Query: 208 KGKNI---KIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIAR- 375
           +  N    KI +KIE   G+ N+  I++E+DGI++ RGDL  E   E   + ++ +I   
Sbjct: 209 RKSNQFKPKIWAKIETLNGVNNIKSILSEADGIVIGRGDLIPETSIEDTPIYEERIIKEV 268

Query: 376 CNRVGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVH 555
                K +I AT +L SM     P+ +E+  + N I  GA   +L+GET+ G  P+  V 
Sbjct: 269 LGDKDKEIIIATHILNSMKNGKMPSISEVESIYNFIKIGATGFLLAGETSIGKAPIRTVE 328

Query: 556 TMANI 570
            + N+
Sbjct: 329 FLNNL 333


>UniRef50_Q3J5D7 Cluster: Pyruvate kinase; n=2; Rhodobacter
           sphaeroides|Rep: Pyruvate kinase - Rhodobacter
           sphaeroides (strain ATCC 17023 / 2.4.1 / NCIB 8253 /
           DSM158)
          Length = 508

 Score = 87.0 bits (206), Expect = 4e-16
 Identities = 56/165 (33%), Positives = 96/165 (58%), Gaps = 9/165 (5%)
 Frame = +1

Query: 46  KGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKGKNIK 225
           +GVNLPG  +D+ A++E+D + L   V +  D++  SF++    +  +   +  +  + +
Sbjct: 309 RGVNLPGSHLDVAALTEEDLAALDVVVAEA-DLVAFSFVQTPGDVRALIAAMEARACHPR 367

Query: 226 ----IISKIENHQGMVNLDEIIAESDG-----IMVARGDLGIEIPPEKVFLAQKTMIARC 378
               I+ KIE   G+  L E+I E+ G     +M+ARGDL +EI  +++   Q+ ++  C
Sbjct: 368 PLPAILLKIETPMGLHLLPELIVEAGGSLPVGVMIARGDLAVEIGFDRLSEIQEEILWLC 427

Query: 379 NRVGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLS 513
                PV+ ATQ+LE MVK+ + +RAE++D   A+   ADCVML+
Sbjct: 428 EAAKVPVVWATQVLEGMVKEGQASRAEVTDA--AMSQRADCVMLN 470


>UniRef50_Q8FLV7 Cluster: Pyruvate kinase; n=6; Corynebacterium|Rep:
           Pyruvate kinase - Corynebacterium efficiens
          Length = 630

 Score = 86.6 bits (205), Expect = 5e-16
 Identities = 65/199 (32%), Positives = 107/199 (53%), Gaps = 14/199 (7%)
 Frame = +1

Query: 34  LGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGA-------ALHEIR 192
           L + KG+NLP   + LP+++E+D   L F V +  D++  SFIR+         AL +I 
Sbjct: 417 LAAYKGINLPDSELPLPSLTEEDLRHLRF-VAKHADIVNVSFIRDTGDVEYVLDALAQIA 475

Query: 193 GILGEKGK--NIKIISKIENHQGMVNLDEIIA-----ESDGIMVARGDLGIEIPPEKVFL 351
              GE  K   + ++ KIE   G  NL +I+      E+ G+M+ARGDL +E+  +++  
Sbjct: 476 EETGEHDKIRELGLVLKIETIPGYENLAQIMLTGMRHENFGVMIARGDLAVELGFDRMAE 535

Query: 352 AQKTMIARCNRVGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKG 531
             + ++A       P I ATQ+LE+M K   P+RAEI+D   A+    +CVML+    KG
Sbjct: 536 VPQLIMALAEAAHIPTIFATQVLENMAKNGLPSRAEITDATLAL--RCECVMLN----KG 589

Query: 532 DYPVECVHTMANICKEAEA 588
            +  + +  ++ + K+  A
Sbjct: 590 PHINDAIKVLSRMSKKLGA 608


>UniRef50_Q8DLH6 Cluster: Pyruvate kinase; n=2; Synechococcus|Rep:
           Pyruvate kinase - Synechococcus elongatus
           (Thermosynechococcus elongatus)
          Length = 506

 Score = 85.8 bits (203), Expect = 1e-15
 Identities = 61/190 (32%), Positives = 102/190 (53%), Gaps = 9/190 (4%)
 Frame = +1

Query: 46  KGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAAL----HEIRGILGEKG 213
           KG+N P   + L  ++  D+  L F      D+I  S++++   +     E+    G+  
Sbjct: 296 KGLNFPDSDLRLCPLTASDREHLAFACRYA-DIIGYSYVQSAEDIALLQRELAHCCGDCA 354

Query: 214 KNIKIISKIENHQGMVNLDEIIAESDG-----IMVARGDLGIEIPPEKVFLAQKTMIARC 378
             + II+KIE  + +  L E+I ++ G     +M+ARGDL +EI  +++   Q+ ++  C
Sbjct: 355 DQMGIIAKIETPKAIRALPEMIIQAAGRQPFGVMIARGDLAVEIGYQRLAEMQEEILWLC 414

Query: 379 NRVGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHT 558
                PV+ ATQ+LE++VKK  P+RAEI+D A A  + A+CVML+    KG Y    V  
Sbjct: 415 EAAHVPVVWATQVLENLVKKGVPSRAEITDAAMA--ERAECVMLN----KGPYVGLAVDI 468

Query: 559 MANICKEAEA 588
           + ++    EA
Sbjct: 469 LDDVLARMEA 478


>UniRef50_Q19Q27 Cluster: Acyl-CoA desaturase-like; n=2; Belgica
           antarctica|Rep: Acyl-CoA desaturase-like - Belgica
           antarctica
          Length = 316

 Score = 81.0 bits (191), Expect = 3e-14
 Identities = 44/69 (63%), Positives = 52/69 (75%)
 Frame = -1

Query: 647 SIGGFTSDTRSLKSCLCQITASASLQMLAMV*THSTG*SPLAVSPESITQSAPSRMALAT 468
           S+G    DT+S    LCQ+ ASAS+ +LAMV  HS+G SPLAVSP++I QSAPSR ALAT
Sbjct: 248 SMGVGWRDTKSRNRFLCQMAASASIWVLAMVVIHSSGYSPLAVSPDNIVQSAPSRTALAT 307

Query: 467 SEISALVGR 441
           SEISA V R
Sbjct: 308 SEISARVAR 316


>UniRef50_Q9U016 Cluster: Pyruvate kinase; n=2; Giardia
           intestinalis|Rep: Pyruvate kinase - Giardia lamblia
           (Giardia intestinalis)
          Length = 517

 Score = 80.6 bits (190), Expect = 4e-14
 Identities = 45/120 (37%), Positives = 66/120 (55%)
 Frame = +1

Query: 226 IISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVIC 405
           +++K+E    ++NL +I+   DGIM+ARG LG E+    +   QK++I      GK    
Sbjct: 264 LMTKVETPLAVLNLKQIVTHVDGIMIARGALGDEMDFSYLPSIQKSIIQIARDSGKMCYI 323

Query: 406 ATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMANICKEAE 585
           AT + ESM +   PTRAE+SDV N + DG D  +L  ET+ G + V  V  +  I    E
Sbjct: 324 ATNVCESMSENVIPTRAEVSDVTNCLGDGCDGFVLCAETSTGHHSVATVKYLVEIIVAVE 383


>UniRef50_Q2JJ60 Cluster: Pyruvate kinase; n=5; Bacteria|Rep:
           Pyruvate kinase - Synechococcus sp. (strain
           JA-2-3B'a(2-13)) (Cyanobacteria bacteriumYellowstone
           B-Prime)
          Length = 476

 Score = 79.8 bits (188), Expect = 6e-14
 Identities = 57/180 (31%), Positives = 97/180 (53%), Gaps = 7/180 (3%)
 Frame = +1

Query: 34  LGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKG 213
           L + KG+N P   + + ++++KD  DL F V    D++  SF++  A L  +   L  + 
Sbjct: 276 LRAEKGLNFPDSQLQIRSLTDKDCQDLDFVVRHA-DLVGYSFVQQPADLQLLVSELERRQ 334

Query: 214 K--NIKIISKIENHQGMVNLDEIIAESDG-----IMVARGDLGIEIPPEKVFLAQKTMIA 372
              ++ +I K+E  + + NL  +IA   G     +M+ARGDL +EI   ++   Q+ ++ 
Sbjct: 335 ARPDLGLILKMETQRAVKNLPALIATVAGCRPLGVMIARGDLAVEIGWLRLGEIQEELLW 394

Query: 373 RCNRVGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECV 552
            C     PV+ ATQ+L+ + K+  P+R E+SD   +    A+CVML+    KG Y +E V
Sbjct: 395 ICEAAQVPVVWATQVLDQLTKEGLPSRPELSDAVMSA--RAECVMLN----KGPYLLEAV 448


>UniRef50_UPI000049906E Cluster: pyruvate kinase; n=3; Entamoeba
           histolytica HM-1:IMSS|Rep: pyruvate kinase - Entamoeba
           histolytica HM-1:IMSS
          Length = 321

 Score = 64.9 bits (151), Expect = 2e-09
 Identities = 50/173 (28%), Positives = 89/173 (51%), Gaps = 2/173 (1%)
 Frame = +1

Query: 28  GMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFA-SFIRNGAALHEIRGILG 204
           G L   KG NL   P     +SE+D ++++  ++   ++ FA SF+     + EI+ +  
Sbjct: 139 GELKPGKGFNLQPHPFVQNQLSERD-AEIVEKLKDVKEVCFALSFV---CVVEEIQDL-- 192

Query: 205 EKGKNIK-IISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCN 381
           +K  N K I++KIE    +  L  I ++ + I + RGD+G+++    +    +       
Sbjct: 193 KKRSNGKYIVAKIEREMDLERLKAISSQCNEIWICRGDMGVQLGFVGMAKFVREYTTFMK 252

Query: 382 RVGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYP 540
           ++  P I A +++E +     PTR+EI  + N I DG + ++LS ET  G YP
Sbjct: 253 QLNCPSIMAGEVMEHLCDNTIPTRSEICYLGNLIADGYNGIVLSDETVFGKYP 305


>UniRef50_A7CFG4 Cluster: Putative uncharacterized protein; n=1;
           Ralstonia pickettii 12D|Rep: Putative uncharacterized
           protein - Ralstonia pickettii 12D
          Length = 1350

 Score = 58.0 bits (134), Expect = 2e-07
 Identities = 42/137 (30%), Positives = 64/137 (46%), Gaps = 7/137 (5%)
 Frame = -3

Query: 618 VIEELPVPDYSFSLL---ANVGHGVNTLDRIVALGSLPGEHHAVSSVEDGVGYVRDLGSG 448
           ++EE+ +  +   LL   A+  HG + LD + A G    +HH + +VE GVG VR LG+ 
Sbjct: 510 LVEEVCIQMHGLRLLGFDADGSHGFDGLDGVAAGGGFRRQHHGIGTVEHGVGDVRHLGAR 569

Query: 447 GTGLLNHGFQHLSRTDHWFSNPIASGDHGLLGEEYLFWRDLDTQISASNHDTIGFSYNLV 268
              + +H F HL   D          DH LL   +        Q++  +HD +G   +L 
Sbjct: 570 RHRVDDHRFHHLRGGDGQLIVFAGQLDHALLQRRHGRVAHFHGQVATRDHDAVGGGQDL- 628

Query: 267 *IDHS----LVIFDLGD 229
             +H+    L   DLGD
Sbjct: 629 -FEHARTDGLGTLDLGD 644


>UniRef50_Q59ZE3 Cluster: Putative uncharacterized protein; n=1;
           Candida albicans|Rep: Putative uncharacterized protein -
           Candida albicans (Yeast)
          Length = 105

 Score = 55.2 bits (127), Expect = 2e-06
 Identities = 29/67 (43%), Positives = 43/67 (64%)
 Frame = -1

Query: 221 MFLPFSPRMPRISCSAAPLRMNDAKIISTPCSTPKSRSDLSFSETAGRSTGMPGRLTPFR 42
           M LP SP+   IS ++  + + +AKI+ T   TP   S +SFS+ AG+ST +PG+LTP  
Sbjct: 1   MSLPSSPKTFLISKTSLAVSIKEAKIMWTLFLTPNLISAISFSDKAGKSTSVPGKLTPLW 60

Query: 41  DPSIPAL 21
           +  +PAL
Sbjct: 61  EEILPAL 67


>UniRef50_Q3JI08 Cluster: Putative uncharacterized protein; n=3;
           Burkholderia|Rep: Putative uncharacterized protein -
           Burkholderia pseudomallei (strain 1710b)
          Length = 989

 Score = 44.8 bits (101), Expect = 0.002
 Identities = 39/115 (33%), Positives = 54/115 (46%), Gaps = 1/115 (0%)
 Frame = +3

Query: 225 DHLQDRKSPGNGQFRRDYS*IRWYHGCSRRSGYRDPSRKGIPRPE-DHDRQMQSGWKTSD 401
           D  +DR++ G  Q RRD    R   G +RRSG RD +R    R E DH  + + G +T D
Sbjct: 251 DRREDREAAGGRQHRRDRRRGRCGDGRARRSGRRDVARGRAERAEADHPARARGG-QTGD 309

Query: 402 LCDSNAGIHG*EAPSHQSRDL*RSQRHPRRS*LRDALRGDCQGRLSCRVCSHHGQ 566
             D++A I    A +     + R +   RR    DA+ G   G +S R    H Q
Sbjct: 310 RRDADARIDDARADADARGGVRRRRGRLRRRRRGDAVGGIGVGPVSGRGGRFHAQ 364


>UniRef50_Q676G7 Cluster: Pyruvate kinase; n=1; Agrobacterium
           tumefaciens|Rep: Pyruvate kinase - Agrobacterium
           tumefaciens
          Length = 334

 Score = 44.8 bits (101), Expect = 0.002
 Identities = 37/132 (28%), Positives = 66/132 (50%), Gaps = 1/132 (0%)
 Frame = +1

Query: 145 IFASFIRNGAALHEIRGILGEKGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGI 324
           I  SF  +   + +++ I   +  +I II+KIE+   + NL  I   SDG+++ARGDLG 
Sbjct: 184 INVSFADSAIIIRQVKSIC--RFDHINIIAKIESKIAVDNLIGINEASDGLILARGDLGN 241

Query: 325 EIPPEKVF-LAQKTMIARCNRVGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADC 501
               + V  +A K +  R  + G P+I AT       K    + +E + +  A   G + 
Sbjct: 242 FYDEQSVINIAHKIVELRPFQAG-PIIFATNYFTEPAKGLALSTSEQATIQEAFKLGVNT 300

Query: 502 VMLSGETAKGDY 537
           ++++ ET+   +
Sbjct: 301 ILVN-ETSSSQH 311


>UniRef50_A5P062 Cluster: Putative uncharacterized protein; n=2;
           Proteobacteria|Rep: Putative uncharacterized protein -
           Methylobacterium sp. 4-46
          Length = 829

 Score = 44.8 bits (101), Expect = 0.002
 Identities = 37/116 (31%), Positives = 47/116 (40%)
 Frame = +3

Query: 234 QDRKSPGNGQFRRDYS*IRWYHGCSRRSGYRDPSRKGIPRPEDHDRQMQSGWKTSDLCDS 413
           QDR++PG    RRD+  +    G  RR   RD    G  R E H  +     +     D 
Sbjct: 246 QDREAPGARPSRRDHGGVGRADGRPRRPRRRDAPGTGAGRAEAHHPRGAPPRQARRGRDP 305

Query: 414 NAGIHG*EAPSHQSRDL*RSQRHPRRS*LRDALRGDCQGRLSCRVCSHHGQHLQGG 581
           +A I          R L R  R  R    RDALR +  G+   RV  HH  H + G
Sbjct: 306 DARIDDQRPGPDPRRGLGRRHRGLRGGRCRDALRRERLGQFPGRVRRHHEPHRRAG 361


>UniRef50_Q56301 Cluster: Pyruvate kinase; n=5; Thermococcaceae|Rep:
           Pyruvate kinase - Thermococcus litoralis
          Length = 220

 Score = 44.0 bits (99), Expect = 0.004
 Identities = 20/67 (29%), Positives = 39/67 (58%)
 Frame = +1

Query: 22  NAGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGIL 201
           N G+L S KG+N+P   + + A++ +D   + F +E GVD I  SF+ +   + +++  L
Sbjct: 154 NGGILFSHKGINIPKANLPIEAITPRDFEIIEFAIEHGVDAIGLSFVGSVYDVLKVKSFL 213

Query: 202 GEKGKNI 222
            +K  ++
Sbjct: 214 EKKSADL 220


>UniRef50_Q0PQH4 Cluster: Pyruvate kinase; n=1; Endoriftia
           persephone 'Hot96_1+Hot96_2'|Rep: Pyruvate kinase -
           Endoriftia persephone 'Hot96_1+Hot96_2'
          Length = 246

 Score = 43.2 bits (97), Expect = 0.007
 Identities = 19/46 (41%), Positives = 27/46 (58%)
 Frame = +1

Query: 28  GMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIR 165
           G L + KG+N  G  +  PA++EKDK D+ F  E   D +  SF+R
Sbjct: 184 GKLSNNKGINKQGGGLSAPALTEKDKQDIKFAAEIDADYLAVSFVR 229


>UniRef50_A5BYI4 Cluster: Pyruvate kinase; n=1; Vitis vinifera|Rep:
           Pyruvate kinase - Vitis vinifera (Grape)
          Length = 314

 Score = 42.7 bits (96), Expect = 0.009
 Identities = 18/37 (48%), Positives = 26/37 (70%)
 Frame = +1

Query: 391 KPVICATQMLESMVKKPRPTRAEISDVANAILDGADC 501
           +  I ATQML S++K   P R + +D+ANA+L G+DC
Sbjct: 207 RKAITATQMLGSIIKSLCPVRVKATDIANAVLGGSDC 243


>UniRef50_Q4JN61 Cluster: CG7362-PA; n=1; uncultured bacterium
           BAC13K9BAC|Rep: CG7362-PA - uncultured bacterium
           BAC13K9BAC
          Length = 254

 Score = 39.1 bits (87), Expect = 0.11
 Identities = 43/165 (26%), Positives = 75/165 (45%)
 Frame = +1

Query: 91  SEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKGKNIKIISKIENHQGMVNLD 270
           S+ DK  + FG E   + I +  I NG  L   + I  + GKNIK   +++       LD
Sbjct: 83  SDIDKY-IAFGKEISPE-IMSFDISNG--LDFFKTIKSKLGKNIKTCVRVKLGTSTEGLD 138

Query: 271 EIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMVKKPRPT 450
           +   E D  M       IE+   KV    K ++   + + +P+  A  ++ +++K    +
Sbjct: 139 DFFKECDYSM-------IEL-DSKVIHDDKIVMRSKDNMCEPIYLA--LMPTLMKGQVQS 188

Query: 451 RAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMANICKEAE 585
           R E  ++ + + +G D + L  ET+ G Y    V  +  I  E+E
Sbjct: 189 REENFEIGHTLEEGFDLIALYQETSHGPYAARSVKCIDEISVESE 233


>UniRef50_Q8CA87 Cluster: Adult male spinal cord cDNA, RIKEN
           full-length enriched library, clone:A330017A19
           product:hypothetical protein, full insert sequence; n=1;
           Mus musculus|Rep: Adult male spinal cord cDNA, RIKEN
           full-length enriched library, clone:A330017A19
           product:hypothetical protein, full insert sequence - Mus
           musculus (Mouse)
          Length = 136

 Score = 37.5 bits (83), Expect = 0.33
 Identities = 23/75 (30%), Positives = 30/75 (40%)
 Frame = -1

Query: 335 GGISIPRSPRATMIPSDSAIISSKLTIPW*FSILEMILMFLPFSPRMPRISCSAAPLRMN 156
           GG+  P  PR   +  +  +    L   W F  L + L F PF   +P   CSA P R  
Sbjct: 3   GGVIAPPGPRRRKLQLEQ-LAREPLACLWVFFFLSLSLFFFPFPFSLPSPLCSAGPCRPG 61

Query: 155 DAKIISTPCSTPKSR 111
           +      P ST   R
Sbjct: 62  NPHPSCPPPSTAARR 76


>UniRef50_A0IJJ4 Cluster: HpcH/HpaI aldolase; n=2; Bacteria|Rep:
           HpcH/HpaI aldolase - Serratia proteamaculans 568
          Length = 287

 Score = 36.3 bits (80), Expect = 0.77
 Identities = 25/97 (25%), Positives = 45/97 (46%), Gaps = 4/97 (4%)
 Frame = +1

Query: 112 LLFGVEQGVDMIFASFIRNGAALHEIRGILGEKGKNIKIISKIENHQGMVNLDEIIAESD 291
           +L G       I  S +R+ A +  +R      GK+ +I   IE  + + +LD++ A +D
Sbjct: 85  MLCGGGTAPGFIVMSMVRSPAEVVFLRETFASAGKHPEIYLTIETVEAITDLDDVAAVAD 144

Query: 292 GIMVARGD----LGIEIPPEKVFLAQKTMIARCNRVG 390
           G++    D    LG+ I    +  A++ M+    R G
Sbjct: 145 GLIFGSADLAATLGVPITWSGMLAARQAMVLASARHG 181


>UniRef50_Q54CD8 Cluster: Putative RNA helicase; n=2; Dictyostelium
           discoideum|Rep: Putative RNA helicase - Dictyostelium
           discoideum AX4
          Length = 1091

 Score = 35.5 bits (78), Expect = 1.3
 Identities = 27/102 (26%), Positives = 48/102 (47%), Gaps = 3/102 (2%)
 Frame = +1

Query: 94  EKDKSDLLF-GVEQGVDMIFASFIRNGAALHEIRGILGEKGKNIKIISKIENHQ-GMVNL 267
           +K  S ++F   +  V+ I     R G A   I G L    + I + +K  +HQ G++ +
Sbjct: 495 QKKSSTIIFVSTKYHVEFIHILLERAGIASTYIHGYLDPVARKINL-AKFRSHQVGVMVV 553

Query: 268 DEIIAESDGIMVARGDLGIEIPP-EKVFLAQKTMIARCNRVG 390
            ++ A    I +    +  + PP EK+F+ +   +AR  R G
Sbjct: 554 TDLAARGIDIPLLDNVINFDFPPKEKIFIHRVGRVARAGRSG 595


>UniRef50_A6RIB2 Cluster: Putative uncharacterized protein; n=1;
            Botryotinia fuckeliana B05.10|Rep: Putative
            uncharacterized protein - Botryotinia fuckeliana B05.10
          Length = 6808

 Score = 34.3 bits (75), Expect = 3.1
 Identities = 18/48 (37%), Positives = 24/48 (50%)
 Frame = +3

Query: 348  PRPEDHDRQMQSGWKTSDLCDSNAGIHG*EAPSHQSRDL*RSQRHPRR 491
            PR    DR+  S +++ D     A I   E PSHQS+D    Q  P+R
Sbjct: 1164 PRDTIEDREQTSSYRSQDKPSETAQIRE-ETPSHQSKDESHDQNRPKR 1210


>UniRef50_A3LQY4 Cluster: Predicted protein; n=1; Pichia stipitis|Rep:
            Predicted protein - Pichia stipitis (Yeast)
          Length = 1931

 Score = 34.3 bits (75), Expect = 3.1
 Identities = 28/98 (28%), Positives = 46/98 (46%)
 Frame = +1

Query: 226  IISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVIC 405
            +IS+   ++    +DE+I + DG++   G   +EIP E      KT +    ++ +PV+ 
Sbjct: 767  VISERATNESKSRVDEVIVDGDGVIEEEGLCRLEIPNE------KTEMEELEKIERPVL- 819

Query: 406  ATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGE 519
                 E        +R E S V  A+ DG D V+ S E
Sbjct: 820  EELATEEEDYTESDSRFEFSGV-EAVEDGNDEVVASHE 856


>UniRef50_Q0EZ03 Cluster: Putative uncharacterized protein; n=2;
           Mariprofundus ferrooxydans PV-1|Rep: Putative
           uncharacterized protein - Mariprofundus ferrooxydans
           PV-1
          Length = 801

 Score = 33.9 bits (74), Expect = 4.1
 Identities = 23/73 (31%), Positives = 36/73 (49%)
 Frame = +1

Query: 433 KKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMANICKEAEAVIWHRQLF 612
           K+   + A+ SD++   L G D  M   E++  D+P + +H MA +  +   VI H +L 
Sbjct: 552 KESTVSPAKFSDLSRYFLSGFDTYM---ESSYLDHPEQVLHLMARLASDFPLVIDHSRLH 608

Query: 613 NDLVSEVKPPIDP 651
               SEV  P  P
Sbjct: 609 FVSSSEVVNPDGP 621


>UniRef50_A7TH49 Cluster: Putative uncharacterized protein; n=1;
           Vanderwaltozyma polyspora DSM 70294|Rep: Putative
           uncharacterized protein - Vanderwaltozyma polyspora DSM
           70294
          Length = 394

 Score = 33.9 bits (74), Expect = 4.1
 Identities = 15/55 (27%), Positives = 30/55 (54%)
 Frame = +1

Query: 211 GKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIAR 375
           G    + SK+   +  +N+  +  +S+G  ++ G+   E+P EK++L  K  +AR
Sbjct: 65  GTERSVKSKVTKPKSQLNITNMTYQSNGDYLSHGEYLNELPKEKIYLENKLELAR 119


>UniRef50_Q9LSA0 Cluster: Emb|CAB62463.1; n=3; Arabidopsis
           thaliana|Rep: Emb|CAB62463.1 - Arabidopsis thaliana
           (Mouse-ear cress)
          Length = 653

 Score = 33.5 bits (73), Expect = 5.4
 Identities = 20/58 (34%), Positives = 28/58 (48%), Gaps = 2/58 (3%)
 Frame = -1

Query: 194 PRISCSAAPLRMNDAKIISTPCS--TPKSRSDLSFSETAGRSTGMPGRLTPFRDPSIP 27
           P +SCS +P R +   ++S PCS   P   SD+    T  R    P   +P +D S P
Sbjct: 350 PSVSCSPSPTRSDSHALVSHPCSRHLPPHPSDI---PTGRRKESYPEEYSPCQDFSPP 404


>UniRef50_Q6IKV8 Cluster: HDC11342; n=2; Drosophila melanogaster|Rep:
            HDC11342 - Drosophila melanogaster (Fruit fly)
          Length = 1115

 Score = 33.5 bits (73), Expect = 5.4
 Identities = 13/23 (56%), Positives = 17/23 (73%)
 Frame = -1

Query: 140  STPCSTPKSRSDLSFSETAGRST 72
            +TPCSTP+   DLSF E A ++T
Sbjct: 949  TTPCSTPRGEDDLSFKEGAPKTT 971


>UniRef50_P23522 Cluster: 2-dehydro-3-deoxyglucarate aldolase; n=27;
           Proteobacteria|Rep: 2-dehydro-3-deoxyglucarate aldolase
           - Escherichia coli (strain K12)
          Length = 256

 Score = 33.5 bits (73), Expect = 5.4
 Identities = 18/40 (45%), Positives = 24/40 (60%), Gaps = 2/40 (5%)
 Frame = +1

Query: 205 EKGKNIKIISKIENHQGMVNLDEIIAES--DGIMVARGDL 318
           +  KNI I+ +IE+ QG+ N+D I A    DGI V   DL
Sbjct: 141 QSNKNITILVQIESQQGVDNVDAIAATEGVDGIFVGPSDL 180


>UniRef50_Q6VZK4 Cluster: CNPV143 ankyrin repeat protein; n=1;
           Canarypox virus|Rep: CNPV143 ankyrin repeat protein -
           Canarypox virus (CNPV)
          Length = 671

 Score = 33.1 bits (72), Expect = 7.1
 Identities = 22/66 (33%), Positives = 33/66 (50%)
 Frame = +1

Query: 79  LPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKGKNIKIISKIENHQGM 258
           +PA+S  D   L F ++ GVD+   +   N A  + I     EK K IK+I  + N+   
Sbjct: 172 IPALSNNDNEMLQFLIDSGVDINQKNRYGNTALHYAI-----EKNKKIKLIETLVNNNAD 226

Query: 259 VNLDEI 276
           VN  +I
Sbjct: 227 VNATDI 232


>UniRef50_Q893T5 Cluster: Flagellar hook-associated protein 1; n=1;
           Clostridium tetani|Rep: Flagellar hook-associated
           protein 1 - Clostridium tetani
          Length = 579

 Score = 33.1 bits (72), Expect = 7.1
 Identities = 20/58 (34%), Positives = 32/58 (55%)
 Frame = -3

Query: 462 DLGSGGTGLLNHGFQHLSRTDHWFSNPIASGDHGLLGEEYLFWRDLDTQISASNHDTI 289
           +LG  GT +  + F  L+  ++ FS P  +G   LLG+ Y  W++L  Q  +SN  T+
Sbjct: 88  ELGVQGTYVERNKF--LNEIENIFSEPSETGISTLLGKFYKGWQELSKQPHSSNARTV 143


>UniRef50_Q5YWM7 Cluster: Putative uncharacterized protein; n=1;
           Nocardia farcinica|Rep: Putative uncharacterized protein
           - Nocardia farcinica
          Length = 430

 Score = 33.1 bits (72), Expect = 7.1
 Identities = 14/57 (24%), Positives = 31/57 (54%), Gaps = 2/57 (3%)
 Frame = +1

Query: 124 VEQGVDMIF--ASFIRNGAALHEIRGILGEKGKNIKIISKIENHQGMVNLDEIIAES 288
           ++ G ++++  A    N    H +RG+LG  G+ I ++      +G  ++D+I+A +
Sbjct: 125 LDDGDEILYSPADHASNVLPWHHLRGLLGRAGRRIDLVPYATTRRGTADIDDILARA 181


>UniRef50_Q1NHC0 Cluster: Putative uncharacterized protein; n=1;
           Sphingomonas sp. SKA58|Rep: Putative uncharacterized
           protein - Sphingomonas sp. SKA58
          Length = 333

 Score = 33.1 bits (72), Expect = 7.1
 Identities = 26/87 (29%), Positives = 37/87 (42%), Gaps = 1/87 (1%)
 Frame = -3

Query: 609 ELPVPDYSFSLLANVGHGVNTLDRIVALGSLPGEHHAVSSVEDGVGYVRDLGSGGTGLLN 430
           + PVP      +A     +N  +  +  G  PG    ++   DG G V  +G G TG+  
Sbjct: 21  DTPVPGPGEVRVALRAASINHRELFITHGQYPGMTVPITLGCDGAGVVDMIGEGVTGVRE 80

Query: 429 HGFQHLSRTDHWFSNPIA-SGDHGLLG 352
                L    +W SN  A + D GLLG
Sbjct: 81  GDEVVLYPARNWGSNRHAPAADFGLLG 107


>UniRef50_Q0YHY4 Cluster: Protein-glutamate O-methyltransferase;
           n=2; Geobacter|Rep: Protein-glutamate
           O-methyltransferase - Geobacter sp. FRC-32
          Length = 300

 Score = 33.1 bits (72), Expect = 7.1
 Identities = 28/98 (28%), Positives = 46/98 (46%), Gaps = 8/98 (8%)
 Frame = +1

Query: 325 EIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMVKKPRPTRAEI--SDVANAILDGAD 498
           E PP    +  + + A C+   +P   A  +LES+ + P+    EI   D+++A L  A+
Sbjct: 107 ESPPSASIMKIRVLCAGCSTGEEPYSIAMALLESL-RYPKAWDVEILAGDLSSACLKKAE 165

Query: 499 CVMLSGETAKGDYP------VECVHTMANICKEAEAVI 594
                GE  KG  P      +ECV   A + +E + +I
Sbjct: 166 TGFYEGERLKGLPPAFREKYLECVDGGAMVREEVKKLI 203


>UniRef50_Q04GL6 Cluster: RecG-like helicase; n=5;
           Lactobacillales|Rep: RecG-like helicase - Oenococcus
           oeni (strain BAA-331 / PSU-1)
          Length = 676

 Score = 33.1 bits (72), Expect = 7.1
 Identities = 18/67 (26%), Positives = 36/67 (53%), Gaps = 2/67 (2%)
 Frame = +1

Query: 172 AALHEIRGILG--EKGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKV 345
           A LH++RG +G  +K     ++S  +   G+  ++ I++ +DG  +A  DL +  P + +
Sbjct: 555 AQLHQLRGRVGRGKKQSYAILVSDPKTQYGIDRMEAIVSTNDGFALAEKDLKLRGPGDVI 614

Query: 346 FLAQKTM 366
            + Q  M
Sbjct: 615 GIKQAGM 621


>UniRef50_A0Y985 Cluster: Zinc-containing alcohol dehydrogenase
           superfamily protein; n=1; marine gamma proteobacterium
           HTCC2143|Rep: Zinc-containing alcohol dehydrogenase
           superfamily protein - marine gamma proteobacterium
           HTCC2143
          Length = 324

 Score = 33.1 bits (72), Expect = 7.1
 Identities = 19/48 (39%), Positives = 26/48 (54%)
 Frame = -3

Query: 579 LLANVGHGVNTLDRIVALGSLPGEHHAVSSVEDGVGYVRDLGSGGTGL 436
           L+ N   G N +D  +  G  P +  AV  VE G G V ++G+G TGL
Sbjct: 32  LVRNTVAGFNMIDTYMRKGLYPVKFPAVMGVE-GAGVVEEVGAGVTGL 78


>UniRef50_Q949D7 Cluster: Putative uncharacterized protein
           C555ERIPDS; n=4; Oryza sativa|Rep: Putative
           uncharacterized protein C555ERIPDS - Oryza sativa (Rice)
          Length = 691

 Score = 33.1 bits (72), Expect = 7.1
 Identities = 19/65 (29%), Positives = 26/65 (40%)
 Frame = -1

Query: 203 PRMPRISCSAAPLRMNDAKIISTPCSTPKSRSDLSFSETAGRSTGMPGRLTPFRDPSIPA 24
           P  P    +AA  +M   K + T  S P+S +        GR+ G  G  T  +    P 
Sbjct: 319 PSHPMTQQNAAAQQMQQNKDVKTNASNPRSNAKQDLGTGKGRAVGTGGSSTKSQGKQFPL 378

Query: 23  LSCCS 9
           LS  S
Sbjct: 379 LSAAS 383


>UniRef50_Q8F846 Cluster: Putative uncharacterized protein; n=2;
           Leptospira interrogans|Rep: Putative uncharacterized
           protein - Leptospira interrogans
          Length = 892

 Score = 32.7 bits (71), Expect = 9.4
 Identities = 26/97 (26%), Positives = 46/97 (47%), Gaps = 1/97 (1%)
 Frame = +1

Query: 199 LGEKGKNIK-IISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIAR 375
           LG++ KN K ++  +   +    LDE   +S G       LG ++ PE++    K  +  
Sbjct: 575 LGQRDKNGKPVLYSLPGSKSGDVLDESACQSHGPATVLASLGFKMTPEQINQYGKLNV-- 632

Query: 376 CNRVGKPVICATQMLESMVKKPRPTRAEISDVANAIL 486
              + + V  A QML     KPRP+   I ++++ +L
Sbjct: 633 --MITRMVAEAGQMLP---HKPRPSEMSIQEISDLVL 664


>UniRef50_A3XHP8 Cluster: Putative uncharacterized protein; n=1;
           Leeuwenhoekiella blandensis MED217|Rep: Putative
           uncharacterized protein - Leeuwenhoekiella blandensis
           MED217
          Length = 526

 Score = 32.7 bits (71), Expect = 9.4
 Identities = 14/43 (32%), Positives = 23/43 (53%)
 Frame = +1

Query: 217 NIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKV 345
           N  +I K+ +  G  N  +++ ESD   +   +L I IPPE +
Sbjct: 391 NFPVIYKVYSRNGWYNKGDLLFESDATNLCAQELTITIPPESI 433


  Database: uniref50
    Posted date:  Oct 5, 2007 11:19 AM
  Number of letters in database: 575,637,011
  Number of sequences in database:  1,657,284
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 706,358,822
Number of Sequences: 1657284
Number of extensions: 15066243
Number of successful extensions: 52092
Number of sequences better than 10.0: 187
Number of HSP's better than 10.0 without gapping: 49586
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 51961
length of database: 575,637,011
effective HSP length: 98
effective length of database: 413,223,179
effective search space used: 58677691418
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

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