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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= tesS0091
         (548 letters)

Database: human 
           237,096 sequences; 76,859,062 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

AY312160-1|AAQ82434.1| 1569|Homo sapiens mucin glycoprotein prot...    33   0.66 
Y13622-1|CAA73944.1| 1587|Homo sapiens latent TGF-beta binding p...    31   2.0  
AF051345-1|AAC39880.2| 1624|Homo sapiens latent transforming gro...    31   2.0  
AF051344-1|AAC39879.2| 1557|Homo sapiens latent transforming gro...    31   2.0  
X63556-1|CAA45118.1| 3002|Homo sapiens fibrillin protein.              30   4.6  
L13923-1|AAB02036.1| 2871|Homo sapiens fibrillin protein.              30   4.6  
AJ001515-1|CAA04798.1| 4870|Homo sapiens ryanodine receptor 3 pr...    30   4.6  
AB177803-1|BAD16739.1| 2871|Homo sapiens fibrillin 1 protein.          30   4.6  
AB001025-1|BAA23795.1| 4866|Homo sapiens brain ryanodine recepto...    30   4.6  
U95299-1|AAC32288.1| 2003|Homo sapiens Notch4 protein.                 27   7.0  
BX284927-1|CAM25850.1| 2003|Homo sapiens Notch homolog 4 (Drosop...    27   7.0  
BX284686-1|CAM26209.1| 2003|Homo sapiens Notch homolog 4 (Drosop...    27   7.0  
AL845509-1|CAI18564.1| 2003|Homo sapiens Notch homolog 4 (Drosop...    27   7.0  
AL845464-12|CAI41803.1| 2003|Homo sapiens Notch homolog 4 (Droso...    27   7.0  
AL662884-27|CAI18362.1| 2003|Homo sapiens Notch homolog 4 (Droso...    27   7.0  
AL662830-9|CAI17543.1| 2005|Homo sapiens Notch homolog 4 (Drosop...    27   7.0  
U89335-1|AAC63097.1| 1999|Homo sapiens notch4 protein.                 27   7.0  
D86566-1|BAA13116.1|  955|Homo sapiens notch related protein pro...    27   7.5  
BC063815-1|AAH63815.1|  647|Homo sapiens NOTCH4 protein protein.       27   7.7  
AB023961-1|BAB20317.1|  502|Homo sapiens notch4 protein.               27   7.8  
AK160380-1|BAD18723.1| 1055|Homo sapiens FLJ00344 protein protein.     29   8.1  
AK097664-1|BAC05137.1|  330|Homo sapiens protein ( Homo sapiens ...    29   8.1  

>AY312160-1|AAQ82434.1| 1569|Homo sapiens mucin glycoprotein protein.
          Length = 1569

 Score = 33.1 bits (72), Expect = 0.66
 Identities = 16/45 (35%), Positives = 24/45 (53%), Gaps = 1/45 (2%)
 Frame = -2

Query: 187  HTFQRVWRDAQCS*-GKQVVAVCMDFFHSSLYHIPKHRTL*RNAC 56
            + F+R W + +CS    Q  A C    HS +YH+P +    R+AC
Sbjct: 1049 NAFRRSWAERKCSVINSQTFATC----HSKVYHLPYYEACVRDAC 1089


>Y13622-1|CAA73944.1| 1587|Homo sapiens latent TGF-beta binding
           protein-4 protein.
          Length = 1587

 Score = 31.5 bits (68), Expect = 2.0
 Identities = 26/77 (33%), Positives = 29/77 (37%), Gaps = 2/77 (2%)
 Frame = +1

Query: 52  GGMRCVTAYG--ALVCGTDYCEKNPCIQPPLVCPKNTEHRARHAGKCACCPACVXLLGEG 225
           G  RCV   G     C  D  E   C Q P  C          +  CAC PA     G G
Sbjct: 655 GSFRCVCPAGFRGSACEEDVDE---CAQEPPPCGPGRCDNTAGSFHCAC-PAGFRSRGPG 710

Query: 226 ATCKIYSKELAKPPPLC 276
           A C+    E A+ PP C
Sbjct: 711 APCQDVD-ECARSPPPC 726


>AF051345-1|AAC39880.2| 1624|Homo sapiens latent transforming growth
           factor-beta binding protein 4L protein.
          Length = 1624

 Score = 31.5 bits (68), Expect = 2.0
 Identities = 26/77 (33%), Positives = 29/77 (37%), Gaps = 2/77 (2%)
 Frame = +1

Query: 52  GGMRCVTAYG--ALVCGTDYCEKNPCIQPPLVCPKNTEHRARHAGKCACCPACVXLLGEG 225
           G  RCV   G     C  D  E   C Q P  C          +  CAC PA     G G
Sbjct: 692 GSFRCVCPAGFRGSACEEDVDE---CAQEPPPCGPGRCDNTAGSFHCAC-PAGFRSRGPG 747

Query: 226 ATCKIYSKELAKPPPLC 276
           A C+    E A+ PP C
Sbjct: 748 APCQDVD-ECARSPPPC 763


>AF051344-1|AAC39879.2| 1557|Homo sapiens latent transforming growth
           factor-beta binding protein 4S protein.
          Length = 1557

 Score = 31.5 bits (68), Expect = 2.0
 Identities = 26/77 (33%), Positives = 29/77 (37%), Gaps = 2/77 (2%)
 Frame = +1

Query: 52  GGMRCVTAYG--ALVCGTDYCEKNPCIQPPLVCPKNTEHRARHAGKCACCPACVXLLGEG 225
           G  RCV   G     C  D  E   C Q P  C          +  CAC PA     G G
Sbjct: 625 GSFRCVCPAGFRGSACEEDVDE---CAQEPPPCGPGRCDNTAGSFHCAC-PAGFRSRGPG 680

Query: 226 ATCKIYSKELAKPPPLC 276
           A C+    E A+ PP C
Sbjct: 681 APCQDVD-ECARSPPPC 696


>X63556-1|CAA45118.1| 3002|Homo sapiens fibrillin protein.
          Length = 3002

 Score = 30.3 bits (65), Expect = 4.6
 Identities = 22/62 (35%), Positives = 26/62 (41%), Gaps = 4/62 (6%)
 Frame = +1

Query: 64   CVTAYGALVCGTDYCEKNPCIQPPLVCP---KNTEHRARHAGKCAC-CPACVXLLGEGAT 231
            C T Y   + GT   + N C Q P  C    KNTE      G   C CP    L  +G +
Sbjct: 2560 CKTGYTPDITGTSCVDLNECNQAPKPCNFICKNTE------GSYQCSCPKGYILQEDGRS 2613

Query: 232  CK 237
            CK
Sbjct: 2614 CK 2615


>L13923-1|AAB02036.1| 2871|Homo sapiens fibrillin protein.
          Length = 2871

 Score = 30.3 bits (65), Expect = 4.6
 Identities = 22/62 (35%), Positives = 26/62 (41%), Gaps = 4/62 (6%)
 Frame = +1

Query: 64   CVTAYGALVCGTDYCEKNPCIQPPLVCP---KNTEHRARHAGKCAC-CPACVXLLGEGAT 231
            C T Y   + GT   + N C Q P  C    KNTE      G   C CP    L  +G +
Sbjct: 2429 CKTGYTPDITGTSCVDLNECNQAPKPCNFICKNTE------GSYQCSCPKGYILQEDGRS 2482

Query: 232  CK 237
            CK
Sbjct: 2483 CK 2484


>AJ001515-1|CAA04798.1| 4870|Homo sapiens ryanodine receptor 3
            protein.
          Length = 4870

 Score = 30.3 bits (65), Expect = 4.6
 Identities = 25/73 (34%), Positives = 33/73 (45%)
 Frame = -2

Query: 226  HLHQVKXHKRDNKHTFQRVWRDAQCS*GKQVVAVCMDFFHSSLYHIPKHRTL*RNACHQH 47
            HL QV+   R  K     VW        K+ V  C  F  + LY++P+HR++  N     
Sbjct: 3460 HLEQVEQPLRSKK----AVWHKLLSKQRKRAVVAC--FRMAPLYNLPRHRSI--NLFLHG 3511

Query: 46   YKNQRFHFEIFEY 8
            Y  QRF  E  EY
Sbjct: 3512 Y--QRFWIETEEY 3522


>AB177803-1|BAD16739.1| 2871|Homo sapiens fibrillin 1 protein.
          Length = 2871

 Score = 30.3 bits (65), Expect = 4.6
 Identities = 22/62 (35%), Positives = 26/62 (41%), Gaps = 4/62 (6%)
 Frame = +1

Query: 64   CVTAYGALVCGTDYCEKNPCIQPPLVCP---KNTEHRARHAGKCAC-CPACVXLLGEGAT 231
            C T Y   + GT   + N C Q P  C    KNTE      G   C CP    L  +G +
Sbjct: 2429 CKTGYTPDITGTSCVDLNECNQAPKPCNFICKNTE------GSYQCSCPKGYILQEDGRS 2482

Query: 232  CK 237
            CK
Sbjct: 2483 CK 2484


>AB001025-1|BAA23795.1| 4866|Homo sapiens brain ryanodine receptor
            protein.
          Length = 4866

 Score = 30.3 bits (65), Expect = 4.6
 Identities = 25/73 (34%), Positives = 33/73 (45%)
 Frame = -2

Query: 226  HLHQVKXHKRDNKHTFQRVWRDAQCS*GKQVVAVCMDFFHSSLYHIPKHRTL*RNACHQH 47
            HL QV+   R  K     VW        K+ V  C  F  + LY++P+HR++  N     
Sbjct: 3456 HLEQVEQPLRSKK----AVWHKLLSKQRKRAVVAC--FRMAPLYNLPRHRSI--NLFLHG 3507

Query: 46   YKNQRFHFEIFEY 8
            Y  QRF  E  EY
Sbjct: 3508 Y--QRFWIETEEY 3518


>U95299-1|AAC32288.1| 2003|Homo sapiens Notch4 protein.
          Length = 2003

 Score = 27.1 bits (57), Expect(2) = 7.0
 Identities = 13/32 (40%), Positives = 16/32 (50%), Gaps = 3/32 (9%)
 Frame = +1

Query: 106 CEK--NPCIQPPLVCPKNTE-HRARHAGKCAC 192
           CE+  N C Q P  CPK T  H    + +C C
Sbjct: 191 CERDVNECFQDPGPCPKGTSCHNTLGSFQCLC 222



 Score = 21.0 bits (42), Expect(2) = 7.0
 Identities = 5/9 (55%), Positives = 7/9 (77%)
 Frame = +1

Query: 100 DYCEKNPCI 126
           D+C  NPC+
Sbjct: 158 DFCSANPCV 166


>BX284927-1|CAM25850.1| 2003|Homo sapiens Notch homolog 4
           (Drosophila) protein.
          Length = 2003

 Score = 27.1 bits (57), Expect(2) = 7.0
 Identities = 13/32 (40%), Positives = 16/32 (50%), Gaps = 3/32 (9%)
 Frame = +1

Query: 106 CEK--NPCIQPPLVCPKNTE-HRARHAGKCAC 192
           CE+  N C Q P  CPK T  H    + +C C
Sbjct: 191 CERDVNECFQDPGPCPKGTSCHNTLGSFQCLC 222



 Score = 21.0 bits (42), Expect(2) = 7.0
 Identities = 5/9 (55%), Positives = 7/9 (77%)
 Frame = +1

Query: 100 DYCEKNPCI 126
           D+C  NPC+
Sbjct: 158 DFCSANPCV 166


>BX284686-1|CAM26209.1| 2003|Homo sapiens Notch homolog 4
           (Drosophila) protein.
          Length = 2003

 Score = 27.1 bits (57), Expect(2) = 7.0
 Identities = 13/32 (40%), Positives = 16/32 (50%), Gaps = 3/32 (9%)
 Frame = +1

Query: 106 CEK--NPCIQPPLVCPKNTE-HRARHAGKCAC 192
           CE+  N C Q P  CPK T  H    + +C C
Sbjct: 191 CERDVNECFQDPGPCPKGTSCHNTLGSFQCLC 222



 Score = 21.0 bits (42), Expect(2) = 7.0
 Identities = 5/9 (55%), Positives = 7/9 (77%)
 Frame = +1

Query: 100 DYCEKNPCI 126
           D+C  NPC+
Sbjct: 158 DFCSANPCV 166


>AL845509-1|CAI18564.1| 2003|Homo sapiens Notch homolog 4
           (Drosophila) protein.
          Length = 2003

 Score = 27.1 bits (57), Expect(2) = 7.0
 Identities = 13/32 (40%), Positives = 16/32 (50%), Gaps = 3/32 (9%)
 Frame = +1

Query: 106 CEK--NPCIQPPLVCPKNTE-HRARHAGKCAC 192
           CE+  N C Q P  CPK T  H    + +C C
Sbjct: 191 CERDVNECFQDPGPCPKGTSCHNTLGSFQCLC 222



 Score = 21.0 bits (42), Expect(2) = 7.0
 Identities = 5/9 (55%), Positives = 7/9 (77%)
 Frame = +1

Query: 100 DYCEKNPCI 126
           D+C  NPC+
Sbjct: 158 DFCSANPCV 166


>AL845464-12|CAI41803.1| 2003|Homo sapiens Notch homolog 4
           (Drosophila) protein.
          Length = 2003

 Score = 27.1 bits (57), Expect(2) = 7.0
 Identities = 13/32 (40%), Positives = 16/32 (50%), Gaps = 3/32 (9%)
 Frame = +1

Query: 106 CEK--NPCIQPPLVCPKNTE-HRARHAGKCAC 192
           CE+  N C Q P  CPK T  H    + +C C
Sbjct: 191 CERDVNECFQDPGPCPKGTSCHNTLGSFQCLC 222



 Score = 21.0 bits (42), Expect(2) = 7.0
 Identities = 5/9 (55%), Positives = 7/9 (77%)
 Frame = +1

Query: 100 DYCEKNPCI 126
           D+C  NPC+
Sbjct: 158 DFCSANPCV 166


>AL662884-27|CAI18362.1| 2003|Homo sapiens Notch homolog 4
           (Drosophila) protein.
          Length = 2003

 Score = 27.1 bits (57), Expect(2) = 7.0
 Identities = 13/32 (40%), Positives = 16/32 (50%), Gaps = 3/32 (9%)
 Frame = +1

Query: 106 CEK--NPCIQPPLVCPKNTE-HRARHAGKCAC 192
           CE+  N C Q P  CPK T  H    + +C C
Sbjct: 191 CERDVNECFQDPGPCPKGTSCHNTLGSFQCLC 222



 Score = 21.0 bits (42), Expect(2) = 7.0
 Identities = 5/9 (55%), Positives = 7/9 (77%)
 Frame = +1

Query: 100 DYCEKNPCI 126
           D+C  NPC+
Sbjct: 158 DFCSANPCV 166


>AL662830-9|CAI17543.1| 2005|Homo sapiens Notch homolog 4
           (Drosophila) protein.
          Length = 2005

 Score = 27.1 bits (57), Expect(2) = 7.0
 Identities = 13/32 (40%), Positives = 16/32 (50%), Gaps = 3/32 (9%)
 Frame = +1

Query: 106 CEK--NPCIQPPLVCPKNTE-HRARHAGKCAC 192
           CE+  N C Q P  CPK T  H    + +C C
Sbjct: 193 CERDVNECFQDPGPCPKGTSCHNTLGSFQCLC 224



 Score = 21.0 bits (42), Expect(2) = 7.0
 Identities = 5/9 (55%), Positives = 7/9 (77%)
 Frame = +1

Query: 100 DYCEKNPCI 126
           D+C  NPC+
Sbjct: 160 DFCSANPCV 168


>U89335-1|AAC63097.1| 1999|Homo sapiens notch4 protein.
          Length = 1999

 Score = 27.1 bits (57), Expect(2) = 7.0
 Identities = 13/32 (40%), Positives = 16/32 (50%), Gaps = 3/32 (9%)
 Frame = +1

Query: 106 CEK--NPCIQPPLVCPKNTE-HRARHAGKCAC 192
           CE+  N C Q P  CPK T  H    + +C C
Sbjct: 190 CERDVNECFQDPGPCPKGTSCHNTLGSFQCLC 221



 Score = 21.0 bits (42), Expect(2) = 7.0
 Identities = 5/9 (55%), Positives = 7/9 (77%)
 Frame = +1

Query: 100 DYCEKNPCI 126
           D+C  NPC+
Sbjct: 157 DFCSANPCV 165


>D86566-1|BAA13116.1|  955|Homo sapiens notch related protein
           protein.
          Length = 955

 Score = 27.1 bits (57), Expect(2) = 7.5
 Identities = 13/32 (40%), Positives = 16/32 (50%), Gaps = 3/32 (9%)
 Frame = +1

Query: 106 CEK--NPCIQPPLVCPKNTE-HRARHAGKCAC 192
           CE+  N C Q P  CPK T  H    + +C C
Sbjct: 191 CERDVNECFQDPGPCPKGTSCHNTLGSFQCLC 222



 Score = 21.0 bits (42), Expect(2) = 7.5
 Identities = 5/9 (55%), Positives = 7/9 (77%)
 Frame = +1

Query: 100 DYCEKNPCI 126
           D+C  NPC+
Sbjct: 158 DFCSANPCV 166


>BC063815-1|AAH63815.1|  647|Homo sapiens NOTCH4 protein protein.
          Length = 647

 Score = 27.1 bits (57), Expect(2) = 7.7
 Identities = 13/32 (40%), Positives = 16/32 (50%), Gaps = 3/32 (9%)
 Frame = +1

Query: 106 CEK--NPCIQPPLVCPKNTE-HRARHAGKCAC 192
           CE+  N C Q P  CPK T  H    + +C C
Sbjct: 191 CERDVNECFQDPGPCPKGTSCHNTLGSFQCLC 222



 Score = 21.0 bits (42), Expect(2) = 7.7
 Identities = 5/9 (55%), Positives = 7/9 (77%)
 Frame = +1

Query: 100 DYCEKNPCI 126
           D+C  NPC+
Sbjct: 158 DFCSANPCV 166


>AB023961-1|BAB20317.1|  502|Homo sapiens notch4 protein.
          Length = 502

 Score = 27.1 bits (57), Expect(2) = 7.8
 Identities = 13/32 (40%), Positives = 16/32 (50%), Gaps = 3/32 (9%)
 Frame = +1

Query: 106 CEK--NPCIQPPLVCPKNTE-HRARHAGKCAC 192
           CE+  N C Q P  CPK T  H    + +C C
Sbjct: 190 CERDVNECFQDPGPCPKGTSCHNTLGSFQCLC 221



 Score = 21.0 bits (42), Expect(2) = 7.8
 Identities = 5/9 (55%), Positives = 7/9 (77%)
 Frame = +1

Query: 100 DYCEKNPCI 126
           D+C  NPC+
Sbjct: 157 DFCSANPCV 165


>AK160380-1|BAD18723.1| 1055|Homo sapiens FLJ00344 protein protein.
          Length = 1055

 Score = 29.5 bits (63), Expect = 8.1
 Identities = 20/68 (29%), Positives = 26/68 (38%), Gaps = 2/68 (2%)
 Frame = +1

Query: 64   CVTAYGALVCGTDYCEKNPCIQPPLVCPKNTE--HRARHAGKCACCPACVXLLGEGATCK 237
            C    G    G    E NPC++    C KN E      +   C C PA     G+G  C 
Sbjct: 931  CTCKAGYTGDGIVCLEINPCLENHCGCDKNAECTQTGPNQAACNCLPA---YTGDGKVCT 987

Query: 238  IYSKELAK 261
            + +  L K
Sbjct: 988  LINVCLTK 995


>AK097664-1|BAC05137.1|  330|Homo sapiens protein ( Homo sapiens
           cDNA FLJ40345 fis, clone TESTI2033031. ).
          Length = 330

 Score = 29.5 bits (63), Expect = 8.1
 Identities = 22/57 (38%), Positives = 28/57 (49%)
 Frame = -1

Query: 224 PSPSKXTQAGQQAHFPACLARCSVFLGQTSGGCMHGFFSQ*SVPHTKAPYAVTQRMP 54
           P P++      QAHFP  L      LG TSGG + G +SQ   P   A  AV + +P
Sbjct: 84  PHPAQDPGLWSQAHFPLSLG-----LGLTSGGHLTGGWSQ---PGNIAAGAVPRALP 132


  Database: human
    Posted date:  Oct 23, 2007  1:18 PM
  Number of letters in database: 76,859,062
  Number of sequences in database:  237,096
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 76,776,575
Number of Sequences: 237096
Number of extensions: 1530546
Number of successful extensions: 3421
Number of sequences better than 10.0: 22
Number of HSP's better than 10.0 without gapping: 3232
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3418
length of database: 76,859,062
effective HSP length: 86
effective length of database: 56,468,806
effective search space used: 5421005376
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

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